ENSGT00760000119043 : Linker Region Query Results

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-------------------MANST--SVTEFLLLGFSSLG-ELQLI----LFVIFLS-LY
LIILSGNIT-IISVIRLDRNLHT--PMYFFLCVLSISETFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFVSCVTQMFF-FLGFAV-TNCLILGAMGYDRYA-AICQ
PLHYHILMSWRVCGTLAATCIASGFLT----SLVGTTLV---------------------
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-------------------------------

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IPSHWVFTLSSSRYAAML-GLNYT--SVSEFILIGFSTFPQHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLLLCALSISEVLYT--FT--------------
I-IPR---MLADLLSTDR-SISFTACASQMFF-SFTPGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGLFI----GLLVTSAIFHLPFCGLSEVHH-FLCHVPP
-LLKLACGNNVPGVALGVGVVCITALLGCFLLILLSYAFIVSTILRIPSTEGRHKA----
-----F--------------STCASHLTV-VVVHYSFASVIYLKPKGLY---SEEGNT--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KIA---IKK------TFLRIWQ----
-------------------------------

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----------------MS-KPNST--FLTEFLFEGFSNFQWHHRLT----FFVVFLT-LY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSMLSISETCYT--VT--------------
I-IPR---MLFGLLNPQQ-TISFQGCATQLFF-YLMFGA-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKTACLYLASGSLGIGL----------VTSVFGLPFCDGFVISH-FFCDVRP
-LLKLSCTD-TTVNEIITLVISVCVLVLPMCLVFISYVLIISTILKIASSEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIVYLKPKSQS---SVGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---MRR------VLGLKILSP--
-------------------------------

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-------------------MANSS--CVTEFFLLGFSSLG-DLQLV----LFVIFLC-LY
LIILSGNIT-IISVIRLDHSLHT--PMYFFLSVLSTSEIFYT--IV--------------
I-LPK---MLVNLLSVLR-TLSFVSCASQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCGQLAATCIVNGFLI----SLVGTTLVFSLPFCGSNKVNH-YFCDISP
-VIHLASAE-TYINQLVIFICGILVLVVPLTCICISYGFIVSTILKIPSTEGKQKA----
-----F--------------STCASHLIV-VIVHYGCASFVYLRPSAKY-T--TGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------MIGKTGFSVKT
L------------------------------

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------------------MGN-CT--TVSTFLLWGFSSFP-ELQSL----LFVVILF-SH
MTILTANVS-IMMAVKLSHNLHT--PMYFFLCGLSFSETCTT--MV--------------
I-LPR---MLVDLLSDNK-TISLPECATQMFF-FFGFSN-NNCFTMVVMSYDRYT-AIHN
PLHYAVRMSQKVCFQLMMASWMVGFLV----SLCVVITVFNLSFYDSNIIPH--FCDISP
-VVSLACDY-TLYHEMAIFVLSAFVLVGSFILIMISYVFIGSIILKMPSAKGKYKA----
-----F--------------STCSSHLTV-VCIHYGFACFVYLRSKDS---DSVLEDM--
-PMAVAYTVL-TPLL----NPIVYSLRNKDI---QVA---LMK------VV---------
-------------------------------

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-------------VAAML-GLNHT--FQSQFILLGFSAFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--LA--------------
I-IPR---MLADLLSAHH-SIPLVACANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRACACLVAWSWIGGSVM----GMVVTTAVFHLTFCGPNEIHH-FFCHVPP
-LLKLACGKNVLVVAKGVGLVCITALLGCCLLILLSYAFIVSTILRIPSAEGRHKA----
-----F--------------STCVSHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---IKK------TFLSKLSLQNS
-------------------------------

----------------------MEWVNETAVRV---------------SALFVVFLLLYL
FTLGTNAII-ISTTMLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCGIQMFSFLFLGCSHSFLLAVMGYGCYMAICNPL--------------LAAACFCGFTV
SLITTSLIFHLPFHSSNQLHHFFCDIPPVPKLASHHSGLSQLVIFMLEIFALVIPLSLIL
VTYIRIISAILK-ISSSAGRYKTFSTCASHLIMVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTTLFNPV-IYNLRNKEFKSALRRTMGQTLYPVN--------------------
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----------------MH-RKNLT--EVTEFVFLGFSRFH-EHQIT----LFVVFLI-LY
TLILAGNVI-IVTIIHIDHHLHT--PMYFFLNILASSETMYT--LV--------------
I-IPR---MLSSLVAQNQ-PISLAGCTTQMFF-FVTLAI-NNCFLLTAMGYDRYV-AICT
PLRYTVIMSKKVCVQLMCGAFGIGLAM----AAVQVTSIFTLPFCYRV-VGH-FFCDILP
-VMKLSCID-TTINEIINFVVSSFAILVPMGLVFISYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SVEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGRNIS----
-------------------------------

----------------------MEWINETVVREFVFLGFSSLAGLQ--RLLFAVFLFLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHRACTGLVAAACTCGFTV
SLVTTSLVFHLPFHSSNELHHFFCDISPVLKLASHHTRLSQLVIFMLGVFVLVIPLLLIL
ISYVRIISAILK-IPSTVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRVMGQTSY-PVH-------------------
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----------------MK-RANFT--EVREFVFQGFSNFQ-EHQLT----LFVIFFA-LY
ILTLTGNVI-IVTIIRTDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFGI-TNCFLLAVMGYDRYV-AICN
PLRYSIIMNWRVCVILASSVCATGFLL----SLVQALAIFRLPFCNTL-IKH-FFCDVRP
-ILDLACTV-PVINQVLTLVLTLMVLTAPAIFLFVSYALIISTILKIASSDGWKKT----
-----F--------------ATCSSHLTV-VVIHYGCASIVYFKPKSEN---SKDQDQ--
-LLSVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLCRKSLS---
-------------------------------

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----------------MQ-RNNFT--EVTEFIFLGFSSFG-KHQIT----LFVVFLT-IY
ILTLAGNII-IVTITHIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFYNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICN
PLRYTIIMSKGMCALLVCGSLGTGLVM----AVLHVPAMFHLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTVNEIINYGVSSFVILVPIGLIFISYVLIVSSILKIVSTEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNTS----
-------------------------------

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----------------ML-HSNHT--TVSEFILIGFSTFPRLQ-LM----FFVLFLL-MY
LFTLLGNLL-IMQTIWSERNLHT--PMYFFLCALSVSEIFYT--FA--------------
I-IPR---LLTDLLSTQH-VISFLGCANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICY
PLRYNVLMSPQGCTWLVASSWFAGIIM----GLVVTLAIFHLNFCGPNEIHH-FTCHVPP
-LVKLACGD-IWGVATGVGIVCITALLGCFLLILTSYAFIVATILRIPSAEGRQKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKSKAPE---SFEGDT--
-LMGITYTIL-TPFL----SPI--------------------------------------
-------------------------------

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----------------MK-KTNCT--HVREFVFQGFSNFQ-EHQLT----LFVVFFV-LY
ILTLAGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSVIMNWRVCVILASSVGATGFLL----SLIQAVAIFRLPFCNTL-IEH-FFCDVRP
-ILDLACTV-PVINDILTLALSLMVITAPATFLFVSYVLIISTILKIASAEGRRKT----
-----F--------------ATCASHLTV-VVIHYGCASIAYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLGKKSLS---
-------------------------------

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----------------MQGFNRTT--TVTQFILVGFSSLG-ELQLL----LFVFFLL-LY
LMILLANAT-IMAVIHFSHTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLIHLLSATK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRFV-AICH
PLRYTLIMSKRLGLGLISLSGATGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR-----------------
-------------------------------

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----------------MK-RTNFT--GVREFVFQGFSNYQ-EFHLT----LFVVFFA-LY
LLTLAGNVI-IVTIIRIDQHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGL--------------------------------------------
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----------------MQ-RKNFT--EVVEFIFLGFSIFG-KHQIT----LFVVLLT-IY
IFTLIGNII-IVTIICIDRHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHSQ-PISLSDCATQMFF-FITLAT-NNCFLLTAMGCDRYV-AICK
PLRYTVIMNRGMCARLVCGSFGTGLVM----AVLHVTAMFSLPFCGTV-VDH-FFCDIYP
-VMKLSCID-TTVNEIINYGVSSFVIFVPVGLIFFSYVLIMSSILKIPSAKGRKKA----
-----F--------------GTCASHLTV-VIVHYGCASIAYLKPKSEN---SVEKDL--
-LISVTYTII-TPML----NPVIYSLRNKEV---KDA---LRR------AVGRNIFK---
-------------------------------

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-----------------------------------------------MR---IFVFITQS
LDLEFSQVRLTPTSEGLSLRV-------ASPLSFSAFYA-----------------LIIV
LTSRTPAPLGESCTCTRRMGN-HT--TVSTFLLWGFSSFP-DLQTL----LFVTILF-SH
ATILAANAS-VMVAIKCTHNLHT--PLYFLLGGLSFSETCTT--MA--------------
I-IPR---L--------K-TLSLSECATQMLF-FFGLSC-SNCFIMSAMSYDRYT-AIRN
PLHYATLMTPKVCFQLMTASWVLGFLV----SLCIVVIIFNLSFCDSNVIQH-FFCDISP
-VMCLACDY-TLYHEMAVFVFSAFVLGGSFILIMISYIFIGSVVMKVPSAKGRCKA----
-----F--------------STCSSHLTV-VCIHYAFAGFVYLRPKDR---DSVREDM--
-LMAVAYTIL-TPLL----NPIVYSLRNKEM---QVA---LRK------VLDNICQFSPY
GK-----------------------------

----------------------MERINETAVTEFVFLGFSSLFELQ--QLLFVVFLLLYL
FTLGTNAVI-LFTILLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLSQKKTISFV
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTTLMSPGVCLCLVAMACACGFTI
SIIITSLVFHLPFHSSNKLLHFFCDISPVLKVASYHTHLSQMVIFMLCALVLVIPLLLIL
ISYIHIIFAILQ-FSSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKNNYTSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRILGRTFFSIQQ-------------------
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----------------MP-AQNYS--TMSEFILFGFSAFPQQLLPV----LFL-------
--------------------LHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHH-SITFVSCAGQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSPHDCARLVAWTWAGGSVM----GMMVTMIVFHLSFCGSNVIHH-FACHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLLLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFPSLFYLKPKGFH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKKL---KNA---INK------NFYRKFCLLSS
-------------------------------

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----------------MK-KENCT--VVSEFVFQGFSSFH-EHQLT----LFVVFLS-LY
LLTLAGNVI-IVTIISIDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLSSLRGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCAQLVWGACSIGLLV----AVIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDILNFIISSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LRR------AIGKKPPA---
-------------------------------

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------------------MKNNQT--IFQEFILLGFSLYL-HVQPF----LCVIIFC-LY
FLTLAGNLS-IMGLTWVDTSLHI--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLEDLLTKSK-SISVISCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICK
PLRYPILMTNVACGQMVASAWVGGFFI----SLIETAMIFKGSFCRPNLIKH-FFCHMRA
-VVRLSCIN-SDLTELIVTLMSLSGLLGTFLLIILTYVLILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPETS-----EGDDT--
-LIAIPYTVI-TPFL----SPIIFCLRNKDM---KNA---FKK------ALGKTIPLKT-
-------------------------------

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--------------------INRT--ILKEFVLVGFSVYP-YAHTF----LSVVFFC-LY
LLTLTGNLA-IMYLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-TPK---MLADLLAKNR-SITIIGCGLQMCF-FLGLGG-TNCVILTLMGFDRFL-AICN
PLRYPLLMTNVVCGQLVVSAWVAGFII----SVTETTLIFRGSFCGPNLVKH-FFCHMRA
-VVRLSCLD-SELTELIVTAISVSGLMGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPGAS-----GGDDT--
-VIAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGKTSSLNK-
-------------------------------

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--------MTTVLRSEVILTENLT--TVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNIT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDCYA-AICH
PLHYPILMGWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSTNKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYICILRTILKIPSAEGRRKA----
-----F--------------STCAAHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLN
-------------------------------

----------------------MEQVNETVVREFVFLGFSSLARLQ--QLLFVTFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYMAICNPLRYSVLMGHGVCMGLVAAACACGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLIL
VSYIRIISAILK-IPSSVGRYKTFSTCASHLIVVTVHYGCASFIYLRPKTNYTSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRTIGQTFYPLS--------------------
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----------MPSRPS-------------------LCC----------------------
--S-IPFFCVSSQAPEKLWGNGTW--LVTEFVLVGFSNLP-HLRTT----LFTLFLL-TY
LVTLSGNVT-IITIIHVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISIPACRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSMIMRPTVCLCLGALVFCSGFSV----ASIETCMIFSSPFCRGARVEH-FFCDIAP
-VLKLSCTQ-GARKALGIFFLSVLVVLVSFLLILLSYTFIVATIVKMPSATGRHKA----
-----F--------------STCAAHLTV-VIVHFGCAAIIYLHPDSG---ASPEWDH--
-LVAMFYTVV-TPXX----XXXXXXXXXXXX-----------X------XRNPGCTRCAT
RR-----------------------------

----------------------MEWVNETTVRQFVFLGFSSLAGLQ--KLLFVVFLLVYL
FTLGTKAII-ISTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFR
GCAIQMFSFLFLICSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACACGFII
SLVTTSMIFHLPFHSSNQLHHFFCDVSPVLKLASHHSHLNQLVIFVLGVFVLVIPLLLIL
VSYVLIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLLNPM-IYSLRNKEFKSALRRPVN---------------------------
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----------------MQRINQTI--RVTRFILVGFSSLG-ELQML----LFVIFLL-LY
MTILLANAT-IMTVIHCSRSLHT--PMYGFLFILSFSETCYT--FV--------------
I-IPQ---LLDHLLSDIK-AISFMACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICF
PLRYMIIMNKRLGLGLISVSGATGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFVLILISYGFIVKTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VIVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KAA---LKR------VFQRPSSAKLI
-------------------------------

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KPENFFFTFLDTIYDLMK-KKNHT--LVNEFTLQGFSSFC-EHQFT----LFIVFFA-LY
MLTLAGNII-TVAIISLDRRLHT--PMYFFLGMLSASETVYT--VI--------------
I-IPK---MLCNLVGLSQ-SISLAGCAAQMFF-FITLAI-NNCFLLTAMGYDRYV-AICH
PLRYTVIMNRRVCIQLVWGACSIGLIV----AMTQVTSVFRLPFCATK-VAH-FFCDIWP
-VMKLSCID-TTVNEILTLIISVLVILVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SKDEDQ--
-LISVTYTVV-TPLL----NPVVYTLRNKEA---KDA---LLR------AIGRKLSCLNT
IN-----------------------------

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----------------NI-ILNSI--KCFEFIFQGFSSFG-DHQFT----LFVVFLA-LY
LFTLAGNVI-IVTIIGLDRHLHT--PMYFFLSMLSVSETVYT--LV--------------
I-IPR---MLVNLLGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICS
PLRYSVIMSKRVCVQLVWGACSIGLIV----AMTQVSAVFRLPFCTTK-VAH-FFCDIRP
-MMKLSCLD-TTINEILTLIISVLVILIPMGLVFISYLLIISAILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LRR------AI---------
-------------------------------

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---------------EKRRGD-FI--SRV----KEYLGQY--TYTR----IFIITLAAER
VFNTAANAS-IMAAIKLSHNLHT--PMYFFLCGLSFSETCTT--MV--------------
V-IPR---MLVDLLSHSK-TIPLPECATQMFF-FFGFSG-NNCFIMAAMSYDRYT-AIHN
PLHYALRMTPKVCFLLMLASWIVGFLV----SLCVVITIFNLSFCNSNIIQH-YFCDITP
-IVSLACDY-NSYHEVTIFILSAFVLVGSFILIMVSYVFIGFIVMKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKNS---DSFGADM--
-LMAVIYTVL-TPLL----NPIVYSLRNKEM---QIA---LRK------VVENANVYP-Q
IAKGEPEHLKSL-ESADR-------------

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-------------------AENLT--RITEFLLLGFSNLR-EKQLV----LFPIFLC-LY
LVILSGNIT-IVTVICLEHSLHI--PMYFFLGVLSVSETCYT--FV--------------
V-LPK---MLINLFSVLR-TISFTSCAVQMFF-FLGFGV-TNCLLLGVMGYDRYA-AICH
PLRYPILMNWRVCRLFAATCGVSGFLI----SLVGTTLVFILPFCNSNKVEH-YFCDISP
-VIHLACGD-SYINEFVIFICGVLVLVFPLTFICISYGFIVSTILKIPSAEGKRKT----
-----F--------------STCASHLTV-VVVHYGC-----------------------
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-------------------------------

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LPTRPPSLSPNPGMAATL-GLNHS--SVSEFILVGFSTFPPHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLADLLSTLH-TIPFAACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLHYNVLMSPHGCTCLVAWSWVGGSVM----GLVVTMAIFHLTFCGPNEVHH-FFCHVPP
-LVKLACGTNVPIVALGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKASQ---SLEGDT--
-LMGITYTIL-TPFL----SPIIFSLRNKEL---QTA---MKK------TFLSKLYPQSP
-------------------------------

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------------------------------------------------------------
----------------MK-KENRT--LVSEFTFQGFSSFH-EHQLT----LFVVFLV-LY
ILTLAGNII-IVTIISLDHHLHT--PMYFFLNMLSASETMYT--LV--------------
I-IPK---MLCNLIGLSQ-PISLAGCATQMFF-FTTLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKKVCTQLVWGACSIGLIV----AMTQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILVPMGLVFISYILIISTILKITSAEGRKKA----
-----F--------------ATCASHLTV-VVVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------VISKKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------INQT--ILQEFILVGFSVYP-HVQTF----LFVVFFC-LY
LLTLTGNLA-IIGLTWLDRALHS--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLADLLAKSR-SISVIGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNMACGQLVASAWAGGFFI----SLIETALIFKGSFCSPNLVKH-FFCHMRA
-VVRLNCLD-SDLTEFIVTVISVSGLLGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHITV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNKNV---KTA---FGK------VLGKARYLYK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TANSS--EVTEFLLLGFSSLG-DVQLV----LFVIFLC-LY
LIILSGNVT-IISVIHLDRSLHT--PMYFFLSVLSTSEIFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFASCAIQMFF-FLGFAV-TNSLLLGVMGYDRYA-AICH
PLRYPILMSWRICGQLAATCILSGFLI----SLMGTTLVFTLPFCGPNKVNH-YFCDISP
-VIRLACAE-TYINELVIFICGVFVLVVPLTFICISYGFIVRTILRIPSTEGKRKA----
-----F--------------STCASHLIV-VIIHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------M-PENYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLADMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWCWAGGSVM----GMMLTLIVFHLTFCGSKEIHH-FVCHVLS
-LLKLACGKETASVTMGVILVCVTALMGCLFFIVLSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------SFHRTFHPLNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----IQFLISTDAASLS-GQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTIWREHSLHT--PMYLFLCALSTSEILFT--VA--------------
I-TPR---MLVDMLSVYR-SITFVACASQMFF-SFTFGY-THSFLLMILGYDRYV-AICH
PLHYNMLMSTRDCARLVSWSWAGGSAV----GMMVTLIVFNLTFCGSNVIHH-FFCHVFS
-LLKLTCGNETSSLTIVVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VIVHYGFASIIYLKPKGPR---SMDSNT--
-LMTTTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKR------SFQRAFCPLSS
-------------------------------

----------------------MEWVNETMVREFVFLGFSSLARLQEQELLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLSILSCSETCYTFVIIPKMLVDLLARKKTISFL
GCAIQMFTFIFFGCSHSLLLAAMGYDRYVAICNPLRYTVLMGHRICVGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDIFPVLKLASQQSYFSQVVIFILCALILVIPLLLIL
VSYIHIISAILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSNYSSSQDVLI
SVSYTILTPLFNPM-IYSLRNKEFKSALCRVMERTIPLPQP-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------SSFCGFLI----SVVVNVLVFSVPFCASNRINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSVEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LKK------VLSRYSLPK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LPLENFT--MVTEFLLLGFSNLN-KMQFV----LFGVILC-LY
LVILSGNIT-VITTICLEHSLHT--PMYFFLSVLSVSETSYT--LV--------------
V-LPK---MLLNLLSVLR-TISFTSCVAQMFF-LLGFGT-TNCLLLGVMGYDRYT-AICH
PLRYPVLMSWWICKLMATTCGISGFLV----SIFGTFLVFSLPFCNSNRINH-YYCDIAP
-VIRLACGD-PYINEAIILIAGIVVLVVPWMFICITYGFIIRTILRIPTTEGKKKA----
-----F--------------STCASHLTV-VVFHYGCASFVYLRPSSKH-T--TDKDK--
-LVTVTYTIV-TPLL----NPMVYTLRNREF---QVA---IQK------VMNWRRFSPKI
I------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------DIMK-KQNHT--LVCEFTFQGFSNFR-EHQLT----LFVVFLA-LY
ILTLAGNVI-IVTIISFDRHLHT--PMYFFLSTLSASETVYT--LV--------------
I-IPR---MLFNLVGLCQ-HISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCLQLVWGACSIGLIV----AMIQVSAVFRLPFCTAK-VAH-FFCDIRP
-VMKLSCID-TTANEILTLIISVLVILIPMSLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VVIHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LWR------AMGKKLP----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRGFNKTT--VVTQFILVGFSSLG-ELQLL----LFVIFLL-LY
LTILVANVT-IMAVIRFSWTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSDTK-TISFMACATQLFF-FLGFAC-TNCLLIAVMGYDRYV-AICH
PLRYTLIINKRLGLELISLSGATGFFI----ALVATNLICDMRFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGK-KA----
-----F--------------VTCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNKEV---KTA---LKR------VLGMPVATKMS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--MINEFILTGFSNLG-DLQIL----LFFIFLL-VY
LTTLTANAT-IMTIIRLDQALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTNP-TISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRATCMHLVLASSFCGFLI----SVVVNVLVFSMPFCASNRINH-FFCDISP
-VIKLGCTD-TNLKEKVIFFLSILVLLFPFVLIFISYVFIVSTILKISSVEGQRKA----
-----F--------------ATCASHLTV-VFVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LRK------VLNRYSFPKTV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RPNFT--VVTEFTFEGFSIFGKEHRLI----LFVVFLV-LY
LLTLVSNAV-ILTVIHLNRQLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPR---MLSSLLSPKQ-AISIPHCATQLFF-YLTFGV-NNCCLLTAMGYDRYV-AICN
PLRYSVIMSKRACIQLASGSWSIGLST----AIIQVSSVFSLPFCGANVISH-FFCDIRP
-LMKLACAD-ITIKELITLLISLCVLVLPMVLIFISYVLIVTTILKIASSEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------ALGRKPLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LICCFFLISDMQTMKVNQT--VLNEFVLVGFSVYP-HVQIF----LFVVFLC-LY
LLTLTGNLA-IMGLTWVDRSLHT--PMYLFLRALSLSETCYT--LA--------------
I-IPK---MLADLRTGHR-SISVVGCGLQMCF-FLGLGG-TNCIVLTLMGYDRFL-AICN
PLRYPLLMTDVVCGQLVASAWAGGFLI----SLIETVLIFRASFCSPNLVKH-FFCHMRA
-VVRLSCAD-RALTESIVTAISVSGLTGTFLLILITYVFVLSTVFRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHFGFAAIVYLKPEAS-----GGDDT--
-LMAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---LRK------VLGKRSFLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QANAT--IWRGFVFLGFSSFG-ELQLL----LFALFLS-LY
LVTLTSNVF-IIVVIRLDSHLHS--PMYFFLSFLSFSETCYT--LG--------------
I-IPR---MLSSLVMGSQ-AISYEGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYTSHMNPTFCAQLVGTSFLTGYLF----GLGMTLVIFQLPFCGSHEIQH-FFCDTPP
-VLSLACGD-TGPSELGILILSLLVLLVSFCSITISYAYILTAILRIPSAKGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------SAFRGKLLGRG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--MITEFILIGFSNLG-DLQIL----LFFIFLL-VY
LTTLTANAT-IMTVIHLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTAP-TISLSGCVAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRATCTQLVLASSFCGFLI----SAVVNVLVFSVPFCSSNQINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPLVLIFISYVFIVSTILKISSVEGQRKT----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LKK------VLSRYLLSKTM
RRD-QSSS-FA---IRNNQTVITYIS-----

----------------------MEQVNKTVVREFVVLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFFGSSHSFLLAAMGYDRYMAICNPLRYSVLMGHGVCMGLMAAACACGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLIL
VSYIRIISAILK-IPSSVGRYKTFSTCASHLIVVTVHYSCASFIYLRPKTNYTSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRTIGQTFYPLS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MV--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFF-FFGLGG-NNCFILAAMSYDRYI-AIHN
PLHYPMLMTKKICFQLIMASCIVGFLV----SLSIVIIIFTFSFCDSYTVQH-FFCDILP
-VANLACDY-TSFHEMAIFMLCAFVLVGSFILIVISYVFILSLVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFACYIYLRPKSS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QVA---LWK------VLENGHRFISR
W------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-QKLKVYCCFFQISDIQMMKINQT--VLKEFILVGFSVYP-HVQTF----LFVVFFC-LY
LLTLAGNLT-IMGLTWVDRSLHT--PMYLFLCSLSFSETCYT--LT--------------
I-IPK---MLKDLLAKDG-NISVIGCSLQMCF-FLGLGG-THCIILTLMGYDRFL-AICN
PLKYPLLMTNIVCGQLVASAWAAGFFI----SLTETALIFRGSFCRSNLVKH-FFCHMRA
-VIRLSCID-SNLTEFIVTLISVSGLLGTFLLIILTYVFIISTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VVIHFGFASIVYLKPEAS-----G-DDT--
-LIAVPYTVI-TPFL----SPIIFSLRNKDM---KNA---FRR------MMGNTIALKN-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LIHRKKCQLILISDVQTMKINQT--VLEEFILVGFSVYP-HAQTF----LFVVFFC-LY
LPTFTGNLA-IMGLTWVDRRLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLADLLVKYR-SISVIGCGLQMNS-FLGLGG-TNCFILTLMGYDRFL-AICN
PLRYPLLMTNMACGKLVVSAWVAGFFI----SVTETGMIFRGSFCHPNLVKH-FFCHMRA
-VVRLSCLD-SKFTEFIVTAISVSGLIGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAIPYTVI-TPFL----SPLIFTLRNKDM---KNA---FRK------VLGKTNSLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MAINQT--TLKEFILIGFSAYP-HVQTF----LFGVFFC-LY
ILTLAGNLT-IMGLTWVDRSLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPR---MLVDLLNNDR-HISVAGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWAGGFLI----SFIQIALTFRVSLCIPNLIRH-FFCNIRA
-VVRLSCID-NSLTELIVTLISMVGLVGTFLLISLTYVFILSSVFKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIAYLKPEAS-----GGDDT--
-LIAIPYTII-TPFL----SPIIFSLRNNDM---KKA---FRK------IMSKTVVLKNN
FGLLLLV------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPQILL
FT-YLN--MFYFFPSLQILAENIT--MVTEFLLLGFSSLG-EIQLA----LFVVFFF-LY
LAILSGNVT-IISVIHLNKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGVIGYDRYA-AICH
PLHYPILMSWQVCGKLAATCAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVRVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVRVTYTIV-TPLL----NPVVYSLRNKDV---QLA---IRK------VLGKKGSL---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ILWDQLFMANSS--SITEFLLLGFSSLG-ELQLV----LFAVFLC-LY
LIILCGNII-IISVIHLDHSLHT--PMYLFLGILSISEIFYT--IV--------------
I-LPK---MLINLFSVLR-TLSFLSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLQYAVLMSWRVCGQLVATCIVSGFLL----SLVGTTLVFSLPFCGSNKVNH-YFCDISP
-VIRLACAD-SYINELVIFIFGVLVLIVPLIFICISYGFIIRTILKIPSAEGKQKA----
-----F--------------STCASHLIV-VIVHYGCASFVYLRPSAKY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IQK------LIGKSGFSL--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-L-FLPHSSLQVIPWRQLPSENIT--MVTEFLLMGFSKLQ-EMQLL----LFVNFLF-LY
LVILIGNIT-IVTVIILEHSLHT--LMYFFLGALSVSETCYT--FA--------------
I-LPK---MLINLLSVLR-IISFTNCALQMFL-FLSFAG-NNCLLLVVMGYDLYV-AICH
LLRYPIIMNWRTCRLLVVTCGVTGFLI----SAAITTLVFSLPFCNSNKINH-YFCDISP
-VIHLACGV-TYVNELFIFICSVFVLVVPFIFICVSYGFIVSTILKIPSTEGKKKA----
-----F--------------STCVSHLTV-VVVHYGCASFVYLRPSSRV-T--SIKDQ--
-LITVTYTII-TPLL----NPMVYSLRNRAV---QVV---IQK------VLLTRCFLY--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PS
QG-SLDLITM-ALCRSIFSMANSS--QVTEFLLLGFSSFG-ELQPV----LFVLFLC-LY
LIILSGNFT-IISVIHLDRSLHT--PMYFFLCVLSTSEVFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFTGCATQMFF-FLGFAI-TNCLLLGVMGYDRYT-AICQ
PLRYPVLMNWRVCGQLAASCIVSGFLI----SLVVTTLVFNLPFCGPNKVNH-YFCDISP
-VIRLACAE-TYIHELVIFICGVLVLLVPLIFICISYGFIVHTILKIPSAEGKRKA----
-----F--------------STCASHLIV-VIVHYGCASSVYLRPSAKY-S--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------MIGKTGVSLK-
-------------------------------

----------------------MEWGNETLVREFVFLGFSSLAGLQ--RLLFIAFLPIYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTELMGPRVCVGLVGAACACGFTI
AQIITSMVFHLPFHSSNQLHHFFCDIAPVIKVASHHTHSSQIVIIMLCALVLVVPLLLIL
VSYIHIISAIVQ-FPSTLGRYKAFSTCASHLIVVTIHYGCASFIYLRLKSTSSSSQDALI
SVSYTILTPLFNPL-IYSLRNKEFRSALRRSVERTISLPQR-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MAVML-GLNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FFCHVPP
-LLKLACGENVLEVAKGVGIVCITALLGCFLLILLSYTFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLGGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIT---MKK------AFLNKLFPQ--
----------NS-------------------

----------------------MEQVNETLMREFVFLGFSSLARLQ--LLLFVVFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLTDLLAKKKTISFL
GCTIQMFSFLFLGCSHSFLLAVMGYDRYMAICNPLNYMVLMGHGVCVGLVAAACACGFTV
SLVTTSLIFNLPFHSSNQLHHFFCDTSPVLKLASHHSHLSQLVLFMLALFALVIPLLLIL
VSYIRIISAILK-IPSSVERYKTFSTCASHLIVITVHYGCASFIYLRPKSNYSSSQDILI
SVSYTILTPLFNPM-IYSLRNREFKTALRRLMGQTSCPVN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MEQVNETVVREFVFLGFSSLARLQ--QLLFVTFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYMAICNPLRYSVLMGHGVCMGLVAAACACGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLIL
VSYNRIISAILK-IPSSVGRYKTFSTCASHLIVVTVHYGCASFIYLRPKTNYTSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRTIGQTFYPLS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLCFRFGNQSMK-TENFT--LITDFVFQGFSSFH-EQQIT----LFGVFLA-LY
ILTLAGTTI-IVTIIRIDHHLNT--PMNFFLSMQPISETVYT--LV--------------
I-LPR---ILSSLVGMNQ-TISLAG----------------------SMGYDCSV-AICN
PLRYTVIMNKRVRIQLVLGACSIGLIV----AITQVTSVCRLPFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVV-------SL-----------------------
------------------------------------------------------------
-----------------------------EV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRGFNKTT--VVTQFILVGFSSLG-ELQLL----LFVIFLL-LY
LTILVANVT-IMAVIRFSWTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSDTK-TISFMACATQLFF-FLGFAC-TNCLLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLELISLSGATGFFI----ALVATNLICDMPFCGPNRVNH-YFCDSAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKKKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNKEV---KTA---LKR------VLGMPVATKMS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MT-DQNHS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTIWREHSLHT--PMYLFLCALSTSEILFT--VA--------------
I-TPR---MLVDMLSTYR-SISFTACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWSWAGGSVM----GMMVTMIVFHLTFCGSNEIHH-FACHVLA
-LLKLACGNETSSVTLGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VIVHYGFASIIYLKPKGPR---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------NYLRKFFP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
VILNFIPLLVSPDAASEA-GQNYS--MVSEFILVGFSSFPHL-QLM----FFLLFLL-MY
LFTLLGNLL-IMVTVWSEHSLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLADLLSTSH-TITSVACASQMFF-SFTFGF-THAFLLTVMGYDRYV-AICH
PLSYNVLMSTRSCARLVSCSWAGGSVM----GLMVTLIVFHLTFCGSNVIHH-FVCHALS
-LLKLACGKETSSVTMGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYSFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-NQNYS--MMSEFILIGFSKFPQQLLPI----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
I-TPY---MLVHMLSTHH-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWSWAGGSVM----GMMVTLIIFHLSFCGSNEIHH-FFCHVLS
-LLKLACGKGTASVTMGVIMVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASLIYLKPRGAH---SMDSNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------TFRRIFCPLSF
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------APLLFLLPF
LT-FFFYFPRVVIPWGQLTPENIT--MVTEFFLLGFSNLQ-EMQFL----LFVIFLC-LY
LAILSGNVT-IVSVIILEHSLHT--PMYFFLGVLSVSETCYT--FV--------------
I-LPK---MLTNLLSVLR-TISFTGCAVQMFF-FLGFAA-NNCLLLVVMGYDRYA-AICR
PLRYPILMNWRTCRILVATCGVSGFLI----SMVITDLVFSLPFCKSNKINH-YFCDISP
-VMNLACGV-TYVNELFIFISSAFVLMVPFVFICISYGFIVSTIVKIPSAEGKLKA----
-----F--------------STCISHLTV-VVVHYGCASFVYLRPSSRV-T--SVKDQ--
-LLTVTYTII-TPLL----NPMVYSLRNRAV---QVA---IQK------M----------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MHSFNRTT--MVTRFVLVGFSSLG-ELQLL----LFVIFLL-LY
LTILLANAT-IMAVIRCSRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSATK-SISFVACAAQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICQ
PLRYTLVMNKRLGLGLVSLSGVTGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFILNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VIVHYGCASIIYLRPRSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLGMPVATKVI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MIASQCFS--FS--------------
IPIPS---FSTH----AS-SEVFSFIFSSRFF-LFGLAS-NNCFIMAAMSYDRYT-AIQN
PLHYHALMTRTICFQLLMASAVAGFLI----SLCITTMIFNLSFCDSNNIRH-FFCDISP
-VVHLACDY-TSYHEMVIFVLSAFVLVGSFILIMISYIFIVFIVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCVHYGFACFVYLRPKSS---DSFSGDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRR------VLQGVFKFFSQ
LTNRKP-LNI---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------EFILVGFSVYP-HAQTF----LFVVFFC-LY
LLTLAGNLA-ILVLTWVDRSLHT--PMYHFLRALSFSETCYT--LA--------------
V-IPK---MLEDLLAKDR-SISVIGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AIFN
PLRYPLLMTSSICGKLVASAWAGGFFI----SLVETALIFRGAFCRPNLIKH-FFCHMRA
-VVRLSCTD-SDLTEFIVTVISVAGLLGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCTSHLTV-VIIHFGFASIVYLKPEAS-----GADDT--
-LIAVPYTVV-TPLL----SPVIFSLRNKDM---KDA---FR------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTMFLLWGFSSFP-ELQNL----LFVVILL-SH
VTILLANAS-IMVAIKFNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---LLVDLLSESK-AISLPECATQMFF-FFGLAA-NNCFILSAMSYDRYT-AIHN
PLHYPIFMTRKICFQLIMASGVIGFSV----SLCIVIIIFSLSFCNSNIIQH-FFCDIAP
-VVALACNC-TFLQKLILLAFTVFVLVGSFILIMVSYIFIVSIVVKMPSAKGRYKT----
-----F--------------STCSSHFTV-VFIHYGFACFVYLRPKNG---DTFRDDT--
-LMAVTYTVL-TPLL----NPIIYSLRNKDM---QTA---LRK------ILGHGIKGFPQ
MV-NKRAQNI---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANHT--ELREFVFQGFSNFQ-EHQLT----YFVVFLA-LY
ILTLASNFI-ILAIIYVDHHLHT--PIYFFLSVLSTSETFYS--LV--------------
I-IPR---LLSSLVGLSQ-SISLEGSGTQIFF-FLGFAI-TNCLLLAVMGYDHYV-AICN
PLRYPVIMNWRVCAILASSICATGFPL----SLVQTVAIFRMPFSSF-------------
-------------------------HAAPATFLFISYV-IISTILKIASAEGWKKT----
-----F--------------ATCASHFTV-VIIHYGCAYIAYFKPKLEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LLR------VLVRKFFS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--AVSTFLLWGFSSFP-GLQTL----LFVTILF-SH
ATILAANAS-VMVAIKCTHNLHT--PLYFLLGGLSFSETCTT--MA--------------
I-IPR---LLVDLLSESK-TLSLSECATQMLF-FFGLGA-NNCFIMSAMSYDRYT-AIRN
PLHYATLMTPKVCFQLMTASWVAGFLV----SLCIVVIIFNLSFCDSNVIQH-FFCDISP
-VMCLACDY-TLYHEMAIFVFSAFVLGGSFILIMISYVFIGSVVMKVPSATGRCKA----
-----F--------------STCSSHLTV-VCIHYAFAGFVYLRPKDR---DSPREDM--
-LMAVAYTIL-TPLL----NPIVYSLRNKEM---QVA---LRK------VLDKKVHPSDG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--AVSTFLLWGFSSFP-GLQTL----LFVTILF-SH
ATILAANAS-VMVAIKCTHNLHT--PLYFLLGGLSFSETCTT--MA--------------
I-IPR---LLVDLLSESK-TISLSECATQMLF-FFGLAA-SNCFIMSAMSYDRYT-AIRN
PLHYATLMTPKVCFQLMTASWVAGFLV----SLCIVVIIFNLSFCDSNVIQH-FFCDISP
-VMCLACDY-TLYHEMAVFVFSAFVLGGSFILIMISYVFIGSVVMKVPSAKGRCKA----
-----F--------------STCSSHLTV-VCIHYAFAGFVYLRPKDR---DSVREDM--
-LMAVAYTIL-TPLL----NPIVYSLRNKEM---QVA---LRK------VL---------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-MANGT--SGIGFVFLGFSSFG-ELQAL----LFVLFLT-LY
LVTLASNIF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-VPR---MLLGLVSGSQ-AISFTGCVAQMFF-SASWAC-ADCFLLAAMGFDRYV-AICA
PLHYSSRMGPGLCAQLVGSSFLAGILF----GLSLTLVIFRLPFCGSHAIQH-FFCDTPP
-VLSLACGD-TGPSELAVLLLSLLVLLASFLLIAISYACILAAVLRMPSVEGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPRAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QGA---LR-------TALRGGFLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-GQNYS--MMTEFILVGFSTFPQHLLPA----FFLLYLL-MY
LFTLLGNLL-IMTTVWSERSLHT--PMYLFLCALSTSEILFT--VA--------------
I-TPR---MLVDMLFTHR-TITWAACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYHVLMSNRGCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNMIRH-FFCHVFS
-LLKLACGNENSSVTLGVILVCVSALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SIQRKLIPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ME-QTNAT--FQRGFVLLAFSSFG-ELQLL----LFPLFLS-LY
LVTLTSNVF-IIIVIRLDSHLHT--PMYLFLSFLAFSETCYT--LG--------------
I-IPR---MLSGLVRGGQ-GISYVGCAVQMFF-SASWAC-SNCFLLAAMGFDRYV-AICA
PLHYANRMNLTLCAQLVGTSFLSGYLF----GLGMTLVIFHLPFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLLSFCLISTSYTYILAAILRISSTEGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIIYSLRNRAV---QTA---LR-------NAFQGGLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HS--TVTTFLLWGFSSFP-EIQNL----LFVVILL-SH
MAILLANAS-IMVAIKLNHSLHS--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSESK-AISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLHYHIFMTPKVCCHLLIASCVIGFLC----SVSITFTIFNLSFCGSKTIQH-FFCDISP
-LVHLACDY-TAHHAVIIFVVSAFVLVGSFVLIMISYAFIVFLVVRMPSAQGRHKA----
-----F--------------STCSSHLTV-VSLHYGFACFVYLIPKNR---DSFHEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---RTA---LRK------VLNSINKMLPC
LAIKKPESLRTT-IEY---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------M-LKNST--FVTEFLFEGFSSFGWQHRLV----FFIVFLT-LY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSLLSISETFYT--IA--------------
I-IPR---MLSGLLSPHQ-AIDIQSCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKACIYLACGSLGIGLGM----AIVQVTSVFGLPFCDGFIIAH-FFCDVRP
-LLKLACTD-TTINDIINLVVSVCVLVLPMGLVFISYVVIISTILKIASVEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LRK------AIGLRPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-KHQVT----LFVIFLI-VY
ILTLAGNFI-IVTIIYVDHHLHT--PMYFFLSMLSSSETVYS--LV--------------
I-IPR---MLSSLLFHDQ-PISLAGCATQMFF-FVTLAI-NNCFLLTAMGYDRYV-AICN
PLHYLFIMNKGTCVGLVCGSFVTGLTM----AVLQVTAMFNLPFCGTV-VNH-FFCDIHP
-VMKLSCVD-TTINEMINYGVSSFVILVPVALIFISYVLIISSILRITTAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KVA---LQR------AMGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYR--TISEFILSGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATVWIERRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLFTHR-SITFVACAIQMFF-SFMFGF-THSFLLMVMGYDHYV-TICH
PLHYNMLMSPRGCAHLVAWTWAGGSVM----GMMVTMMVFHLTFCGSNVIHH-FLCHVLS
-LLKLACGSKTSSVIMGVMLVCVTALIGCLFLIILSFVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVMHYSFASLIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFCRRFCPLSS
-------------------------------

----------------------MEQINETVVREFVFLGFSSLARLQ--LLLFFIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLTVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGPRVCLGLVATACASGFIV
AQIITSLIFHLPFHSSNRLHHFFCDISPVLKLASHHTHFSQIVIFLLCTLVLVIPLLLIF
LSYVHIISAILQ-FPSTLGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSGQDALI
SVSYTILTPLFSPM-VYSLRNKEFKSALRRVVGRAISL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---EYFFTFLDTIYDLMK-KENHT--LVSEFTFQGFSSFC-EHQFT----LFIMFFA-LY
MLTLAGNII-TVAIISLDHHLHT--PMYFFLSVLSASETVYT--VI--------------
I-IPK---MLCNLIGLSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICH
PLRYTVIMNRRVCIQLVWGACGIGLIV----AMTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SKGEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEA---KEA---LLR------AIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MAVTL-GRNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATIWSEHSLHT--PMYRFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSALH-SIALLACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPSEIHH-FACHVPP
-LLKLACGKNVLAVAKGVGMVCITALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLSKLYPE--
----------KM-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KTNCT--HVREFVFQGFSNFQ-EHQLT----LFVIFFV-LY
ILTLAGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSVIMNWRVCVILASSVGATGFLL----SLIQALAIFRLPFCNTL-IEH-FFCDVRP
-ILDLACTV-PVINDILTLALSLMVITAPATFLFVSYVLIISTILKIASAEGRRKT----
-----F--------------ATCASHLTV-VVIHYGCASIAYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLGKKYLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------ISFQAPEEQQGNRTW--LVTEFVLVGFSNLP-DLRTI----LFTLFFV-TY
IITLSGNAT-IITIIHVDRTLHT--LMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISIAGCQAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSTIMRPTISFCLGALVFCSGFSV----ALIETTMIFSSPFCHSNRVEH-FFCDIAP
-VLKLSCTE-SASKALVIFFLSILVVLVSFLLILFSYAFIVATILRIPSAAGRHKA----
-----F--------------STCTAHLTV-VIVHFGCAAIIYLRPESGG-N--HDQDR--
-LVAVFYTVV-TPLM----NPVVYTLRNKEV---RVA---LRR------NLARSCGS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MM-RRNHT--VVSEFVFQGFSSFQ-EYKFT----LFMVFLT-LY
LLTLTGNAI-IMIIIGIDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLASLVGSSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRCV-AICN
PLRYSVIMNKRVCAQLVWGSCNIGLLV----AIIQIASVFRAPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIVNFIISSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKKPIA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MKGFNKTP--GVTQFVLVGFSSLR-ELQLL----LFVIFFL-LY
LTILVANVS-IMAVIRFSQTLHT--PMYGFLFILSFSESYYT--FV--------------
I-IPQ---LLAHLLSDTK-IISFLACATQLFF-FLGFAC-TNCFLIAVMGYDCYV-AICH
PLRYTLIMNKRLWFGLVSLSGVTGFFI----ALVATKLICDMPFCGPNRVNH-YFCDL--
-----ACTD-THLKELALFSLSILVIMVPFLLILTSYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCS---------NS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLKNQEV---KTA---LKR------VLGITVAIKMN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KSNTT--FVTEFLFEGFSGFGWHHRLA----FFAIFLA-LY
FLTLSGNVI-IVSIIHLDHHLHT--PMYFFLTILSISDTCYT--VT--------------
I-IPR---MLSDLLNPYH-TIAFRDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGRKACVHLASGSLGIGLGM----AIVQVTSVFSLPFCDRFVIPH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVFVLILPMGVVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYMKPKSQS---LLGQER--
-LISVTYTLI-TPLL----NPLVYTLRNKEV---KDA---LRR------AMWQKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------RENHT--VVTEFIFQGFFSFH-EHKLT----LFVVFLT-LY
LLTLASNVI-IVTIIGIDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLSSLIGLSQ-PISLAGCATQMFL-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNRRVCTQLVWGACSIGLLV----AIIQISSVFGLPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIMNFIISSLVIVVPKGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---MRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LHR------AIGKKPLA---
-------------------------------

----------------------MEQGNETLVREFTFLGFSSLAGLQ--QLLFIAFLPLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTELMGHRVCVGLVAVACACGFTI
AQIITSLVFHLPFRSSNQLHHFFCDISPVLKVASHHTHLSQIVIIVLCALVLVIPLLLIL
VSYIHIISAIVQ-FPSTLGRYKAFSTCASHLIVVTIHYGCASFIYLRLKSTSSSSQDALI
SVSYTVLTPLFNPL-IYSLRNKEFRSALRRAVGRTLSLPQR-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------CFMANSS--FVTEFLLLGFSSLG-ELQLV----LFVLFLC-LY
LVILSGNIT-IISVVYLDHNLHT--PMYFFLGVLSISEIFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFVSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLRYPILMSWRICGQLAASCIVSGFLI----SLMGTNLVFSLPFCGSNKVNH-YFCDISP
-VIRLACAE-SYVNELVIFICGVLVLVVPLIFICFSYGFIVHTILKIPSAEGKRKA----
-----F--------------STCASHLIV-VTVHYGCASFVYLRPSAKY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------MFGKTGLLLKT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSQ-SISLGGCATQMFF-FVTFGI-TNCFLLTVMGYDHYV-PICK
PLRYTIIMNKKGCIQLVLGPCSIGLIA----AMTQVSAMFRLPFCATE-VAH-FFFDIQP
-VMKLSCID-ATVSEILTLIISVLVLVVPM---------------------GRKKA----
-----F--------------ATCTSHFTV-VSVHYGCASITYLKPKSKN---SRDEDQ--
-LISVTYTVI-TPVL----NPVVYTLRNKEV---KNA---LCRA------TDRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANST--SVTDFLLLGFSSLG-ELQLV----LFVLFLS-LY
LIILSGNIT-IISVIRLDRSLHT--PMYFFLCVLSISETFYT--VV--------------
I-LPK---MLVNLLSVLR-TLSFVSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLYYNILMRWSVCGQLAATCIASGFLI----SLVGTTLVFSLPFCDSNKVNH-YFCDISP
-LIHLACGD-THISELVIFICGVLVLVVPLFLICISYGFIVHTILRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-TVNCT--QVREFVFQGFSNFQ-EHQLT----LFIVFFT-LY
ILTLTGNLI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-SISLECCGIQLFF-FLGFGI-TNCLLLAVMGYDRYV-AICN
PLRYSIIMNWRVCVTLASSVCVTGFLL----SLVQAMAIFRLPFCNTL-IKH-FFCDVRP
-ILDLACMV-PVINDILTLVLTLMVITAPATFLFVSYVLIISTILKIASADGWKKT----
-----F--------------ATCSSHLTV-VVIHYGCASTVYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRR------VLCRKYLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RSNFS--VVTEFILVGFSTFPH-LQLM----FFFLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLADLLSTYH-AIVFAACASQMFF-SFMFGF-THSFLLTIMGYDRYV-AICH
PLRYNVLMSPRGCSCLVAWSWVGGSVM----GLVVTMAVFRLTFCGPNEIHH-FACHVPP
-LLKLACGTDVPIVALGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKAPQ---SLEGDT--
-LMGITYTIL-TPFL----SPIIFSLRNKEL---KTA---MKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MAT
KLSHSTYSVLYSQAPEKQQENATW--LVTEFVLVGFSNLP-HLRYT----LFGLFFL-TY
LVTLSGNIT-IIIIIQEDRTLHT--PMYRFLAVLSLSETSYT--LV--------------
T-IPN---MLAHLLMESQ-AISIPGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLRLGALVFCSGFSV----ASIETSMIFSSPFCGSNRVEH-FFCDIAP
-VLKLSCSK-SAGKALAIFFLSVLVVLVSFLLVLLSYAFIVAAIVRIPSAAGRRKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPESGA-R--PEQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRR------TLGRSRGVFQ-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SR-A
LSSLHPLQPSTPRFSSMP-RPNFT--AVTQFTFEGFSIFSWQYRLI----LFVVFLV-LY
LLTLASNAL-ILTVIRFSRQLHT--PMYFFLSVLSVSETCYT--VA--------------
I-IPR---MLSSLLSPQQ-PIAAQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKRTCIQLASGSWSIGLST----AITQVSSVFSLPFCDSNIISH-FFCDIRP
-LMKLACAD-TTIKELVTLLISLCVLVLPMVLVFISYVLIVSTILKMASADGRKKA----
-----F--------------ATCASHLTV-VVVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LLR------ALGKKPL----
-------------------------------

----------------------MEWTNDTVVREFVFLGFSALAGLQ--QLLFVVFLLLYL
FTLGTNAII-MSTIVLDRALHTPMYFFLSVLSCSETSYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHGVCLGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSHLSQLVIFMLCALVLVAPLLLIL
VSYIRIISAIVQ-FPSTLGRYKAFSTCASHLIIVIVHYGCASFIYLRPKSNYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRVVGRTISLPH--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VNQGNFS--SVTEFLLMGFSSLG-KIQLI----LFALFLC-LY
MIILSGNIT-IVTVIRLDHSLHV--PMYFFLGILSISETCYT--LV--------------
I-LPK---MLINLLSLLR-TISFTNCATQMFF-FLGFAI-TNCMLLGVMGYDRYV-AICH
PLRYPVLMCWKICGQLAASCAGIGFML----SLLGSLLVFELPFCGPNKINH-YFCDISP
-VIQLACTD-TYINELVIFIGGVLALMVPLTFICFSYGFIVRAILRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSTKY-S--SSKDR--
-LVTVTYTVV-TPLL----NPMVYSLRNKDV---QVA---IRK------MIAWGGFYPKA
KI-----------------------------

----------------------MEWVNETALREFVFLGFSSLARLQ--QLLFIVFLLFYL
FTLGTNAIIIISTIVLDRALHTPRYFFLAILSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAIGYDRYAAICNPLRYTELMRYRVCVGLVVAACACGFTV
AQIITFLVFHLPFHSSNELHHFFCDISPVLMLASHHTHFVK-------------------
-------------------L Y KAFSTCASHLIVATVHYGCASFIYLRPKSNYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKEFKSGLCRVVGRTISLPQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MERVNETMVREFIFLGFSALASLQ--RLLFVIFLLVYL
FTLGTNAII-ISTIVLDRVLHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLAEKKTISFL
GCTIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMEHGLCVGLVLAACACGLTV
SVVTTSLVFHLPFHSSNKLHHFFCDISPVLKLASHHSHLSQLVIFMLGVFVLVIPLLLIL
ISYVHIISAILK-IPSSVGRYKAFSTCASHLIVVIVHYGCASFIYLRPKTNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRTMGQTSYPIS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MEWVNETVVREFVFLGFSSLAGLQ--QLLFLVFLVLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGSGVCVGLVAAACACGFTV
SVVTTSLVFHLPFHSSNKLHHFFCDISPVLKLASHHSRLSQLVIFMLGVFVLVIPLLLIL
ISYVRIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYTLRNAEFKSAIRRAMSWISN-PF--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KSNTT--FVTEFLFEGFSGFGWQHRLA----FFAIFLA-LY
FLTLSGNVI-IVSIIHLDHHLHT--PMYFFLAILSISDTCYT--VT--------------
I-IPR---MLSDLLNPYH-TIAFRDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGRKACVHLASGSLGIGLGM----AIVQVTSVFSLPFCDRFVIPH-FFCDVRP
-LLKLACTD-TTINEIINFVVSVFVLILPMGVVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYMKPKSQS---LLGQER--
-LISVTYTLI-TPLL----NPLVYTLRNKEV---KDA---LRR------AMWQKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KKNST--VVTEFLFEGFSSFGWQHRLG----LFIAFLT-LY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSMLSISETFYT--IA--------------
I-IPR---MLAGLLNPRQ-AIDIQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKACILLASGSLGIGLSM----AIVQVTSVFGLPFCDGFVIAH-FFCDVRP
-LLKLACTD-TTINEIINFVVSVCVLVLPMGLVFISYVVIISTIFKISSAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LRK------AIGLRPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------LQRKKIKIV-VM--SLKDYLSLLYSIYS-EFPIT----FFFVLTQRPD
LGIPAADVS-IMVAIRLSHNLHS--PMYFFLCGLAFSETCTT--MV--------------
I-IPH---TLVDLLSDSK-MISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHN
PLRYSMLMTRKICFQLMMASWVVGILV----SLCIVIIVFSLSFCDSSIIQH-FFCDISP
-VVSLACDS-TYLHELVIFMLSAFVLVGSFILIMISYVFIVTIVVKMSSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFASFVYLRPKNI---DSFHEDM--
-LMAVTYTML-TPLL----NPIVYSLRNKEM---KLA---LRK------VLGYANRFITQ
MANKKKLEHLEN-VQNFNK------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MLMS-QPNCT--FVTKFLFAGFSTFGWQHRLV----FFVVFLM-LY
LVTLSGNVI-IVTIIHLDRHLHT--PMYFFLSILSISDTCYT--VV--------------
I-IPR---MLYGLLNPQQ-TISFQDCATQLFF-YLTFGI-NNCFLLMAMGYDRYV-AICN
PLRYSVIIGKRACNHLVLGSLGIGLSM----AIVQVTSVFSLPFCDAFVIPH-FFCDVRP
-LLKLACTN-TTVSEIINFVVSVFVLILPMGVVFISYVLIISTILKIASKEGRKKA----
-----F--------------ATCTSHLTV-VIIHYGCTSIIYLQPKSQS---FLGQDR--
-LISVTYTVI-TPLLNKKMNPLVYRARGKEV---KDA---LCK------ALGKKPISS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MW-GANHS--TVTEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSERSLHT--PMYLFLCALSISEILYT--FV--------------
I-IPR---MLADLLSTHH-SITFVACGNQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPHGCACLVAWSWIGGSVM----GMVVTTAVFQLTFCGPNEIRH-FFCHVPP
-LLKLACGENVPVVAKCVGLVCITVLLGCCLLILLSYAFIVSTILRIPSAEGQHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-KHQIT----LFVVFLT-VY
ILTLAGNII-TVTVIRIDHHLHT--PMYFFLSMLASSESVYA--LV--------------
I-VPR---MLSSLIFHNQ-PISLAGCATQMFF-FVVLAT-NNCFLLTAMGYDCHV-AICR
PLRYTVIMSKGLCAQLACGSFGTGLAV----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMNLSCTD-TTINEIINYGVSSFVIFMPIGLIFISYVLIISSILKIASAEGR-KI----
-----F--------------ATCASHLTV-VIVRYGCASIAYLN----------------
-------------------------LRNKEV---KDA---LRR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------KANHNNFS--SVTEFLLLGFSNLG-ETQLI----LFAVLLC-LY
LIILSGNIT-IVTVIRLDRSLHI--PMYFFLGILSISETCYT--FV--------------
I-LPR---MLINLLSLLR-TISFINCAIQMFF-FFGFAV-TNCMLLGIMGYDRYA-AICH
PLRYSILMSWQICGQLAATCAAIGFLS----SLIGSLLVFEQTFCGPNEINH-YFCDISP
-VIQLACTD-TYINELVIFSGGVLVLMVPLIFICISYGFIVCTILRIPSTEGKRKA----
-----F--------------STCASHLTV-VIVHFGCASFVYLRPSAKF-S--SSKDR--
-LVTVTYTVV-TPLL----NPMVYSLRNKDV---QMA---IRK------VIGRRGFYSKA
L------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPQILI
FT-YLN--MFYFFPPLQILAENLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IISVIHLDKSLHT--PMYLFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCALQMFF-FLGFAI-TNSLLLGVMSYDRYA-AICH
PLHYPILMSWQVCGKLVAACAIGGFLA----SLTVVNFVFSLPFSSANKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--VITEFILIGFSNLG-DLQIL----LFFIFLL-VY
LTTLMANAT-IMMVIRLDRALHT--PMYFFLFVLSCCETCYT--LV--------------
I-VPK---MLTNLLSTIP-TISFSGCVVQLYL-FVGLAC-TNCFLIAVMSYDRYV-AICN
PLNYTLIV------------SFCGFLI----SVIVNILVFSVPFCASNRINH-FFCDISP
-VIKLSCTD-TNLKQMVIFFLSILVLLVPLVLIFISYVFIVSTILKISSVEGQCKA----
-----F--------------ATCASHLTV-VIIHYGCASFIYLRPKSLY-F--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KMA---LRK------VLSRCSYSK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RLNFT--AVTEFIFEGFSIFGWQHRLF----LFGVFLV-LY
LLTLASNAI-ILTVIHLNRQLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPR---MLSSLLNSQR-VISIPDCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKTCIQLASGSWSIGLST----AIIQVSSVFSLPFCGTNIISH-FFCDIRP
-LMKLSCAD-TTIKEFITLLISLCVLVLPMVLIFISYVLIVTTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSHN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------ALGRKPLFL--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MR-TANHT--EVREFTFQGFSNFQ-EHQLT----LFVVFLA-LY
ILTLAGNVI-IVTVIHFDHHLHT--PMYFFLTVLSTSETFYS--LV--------------
I-IPR---MLASLVGLSQ-SISLEGCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSVTMNWRVCVTLASLVCATGFSL----SLVQAVAIFRLPFCRTR-IEH-FFCDVRP
-VLDLACAT-PVINDILTLIISLLAITAPATFLFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VVVHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYGLKNKDV---QDA---LRR------MVGRKSL----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---NSAFLLSNSGIASML-GPNHT--SVSEFILIGFSTFPHLQ-LM----FFVLFLL-MY
LFTLLGNLL-IMMTIRNERSLHT--PMYFFLCALSISEIFYT--FA--------------
I-IPR---LLTDLLSTHH-AISFLGCANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSSRGCTWLVASSWLGGMVM----GLVVTLAIFHLYFCGPNEIHH-FACHVPP
-LVKLACGD-IWAVAMGVGMVCITALLGCFLLILISYAFIVATILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKTPE---SLEGDT--
-LMGITYTIL-TPFL----SPIIFSLRNKEL---KNA---INK------VFFSNFCPQKL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TTSKFILFGFSAFPQELLPS----A---------
-----------------LHRLHR--PMDLFLWTLSISEILFP--VS--------------
V-TPC---MLADLISTHR-SITFVACTNQMFF-SFMFGF-THSFLLMVTGYDCYV-AICH
PLHYHVLMSPHGCAHLVAWTWAGGSVM----GIMVTSIVFHLTFCRSNGIHH-LACHVLS
-LLKLACGDKTSSVIMGVMLVHVTALIGCLFLCILSYVFIVAATLRIPS-----------
--------------------------------------------PKGPH---SMYSDT--
-LMATTCTVF-TAFL----NPIMFSLRNRS------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VNHANFS--SVTEFLLLGFSNLG-NIQFI----LFVVFLC-LY
LIILSGNIT-IVTVIRLDHSLHI--PMYFFLGILSISETCYT--FV--------------
I-LPK---MLINLLSLLR-TISFTSCAIQMFF-FLGFAI-TNCMLLGVMGFDRYA-AICH
PLRYPILMSWQVCGQLAAMCAVTGFLL----SLLGSLLVFELPFCGPNKINH-YFCDISP
-VIQLACTD-TYINELIIFIGGVLALMVPLTFICISYGFIVHTILRIPSVEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSARH-S--SGKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QMA---IRK------LIGRRRF----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-NENHT--VVSEFTFQGFTSFH-EHQLT----LFIVFFS-LY
TLTLAGNVI-IVTVISADHHLHT--PMYFFLSMLSASETVYT--LI--------------
I-IPK---MLCNLVGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLAAMGYDRYV-AICN
PLRYTIMMNKRVCIQLVWGACSIGLIV----AMTQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TMDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------VIGRKLS----
-------------------------------

----------------------MEWANETLVAEFVFLSFSSLGGLQ--RLLFAVFLLVYL
FMLGTNAII-VSTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAHKKSISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTLLMGHGVCMGLVAAACACGFIV
AQIITSLVFHLPFHSSNQLHHFFCDIFPVLKLASHYSYLSQLVVFVLGVFVLIIPLLLIL
VSYIRIISAILK-IPSSVGRYKTFSTCASHLIVITVHYGCASFIYLRPKSNYSSSQDTLI
SVFYTILTPLFNPM-IYSLRNKEFKSALQRTMTQTSCLKPH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------RYQSRKMIPSANLT--RINEFLLLGFSYLQ-EKQLV----LFPLFLC-LY
LFILSGNIT-TVTAIFLEHKLHT--PMYYFLSILSVSETFYT--IV--------------
I-LPK---MLLNLLSVLR-TISFINCAVQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLRYPILMSWRVCGQLSVTCGILGFMI----SLIMVNLIFSLPFCNSNKINH-YFCDISP
-VIRLACTD-SETREFIIFILGALVLVIPFFFICISYLSILKTIMKIPSTEGKKKA----
-----F--------------STCASHLTV-VIIHYGCASFIYLRPTASY-I--SNKDR--
-LVTVTYTII-TPLL----NPIVYSLRNKDV---QMA---IRK------VLNHYVI----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NSS--CVTEFLLLGFSSFG-ELQLV----LFVVFLC-LY
LIILSGNIT-IISVIYLDHSLHT--PMYFFLCVLSTSEIFYT--IV--------------
I-LPK---MLINLLSILR-TLSFMSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLYYPILMSWKVCGQLAATCIVSGFLL----SLMGTTLVFSLPFCGSNKINH-YFCDISP
-VIRLAYGE-TYINELVIFIFGVIVLIVPSIFICISYGLIVHTILKIPSAEGKQKA----
-----F--------------STCASHLVV-VIVHYGCASFVYLRPSAKY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------MIGKT------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MNTAPTVDAQD-------SGPAGVEWTAG-----------------A---
-EL-RDTAGATSTAPEKLWGNGTW--LVTEFVLVGFSNLP-HLRTT----LFTLFLL-TY
LVTLSGNVT-IITIIHVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISIPACRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSMIMRPTVCLCLGALVFCSGFSV----ASIETCMIFSSPFCRGARVEH-FFCDIAP
-VLKLSCTQ-GARKALGIFFLSVLVVLVSFLLILLSYTFIVATIVKMPSATGRHKA----
-----F--------------STCAAHLTV-VIVHFGCAAIIYLHPDSL---TL--WC---
-------------------------------------------------------TRCAT
KR-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--VITEFVLVGFSSLG-DLQIL----LFIIFLL-VY
LTTLMANVT-IMTVIRIDRTLHT--PMYFFLFILSCSETCYT--LV--------------
I-IPK---MLTNLLSTDK-TISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYMLIVSQATCIQLVLTCAFCGFMI----SVIVNILVFSLPFCASNRVNH-FFCDISP
-VIKLGCTD-TNMKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCISHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPML----NPLVYTLRNKEV---KTA---LTK------VLSRYSFPKSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TA-GQNYS--MVSEFILVGFSTFPQHLLPA----FFLLYLL-MY
LFTLLGNLI-IMATVWSERGLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSSHR-SITFVACASQMFF-SFTFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSTRTCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNVIHH-FFCHAFS
-LLKLSCGKETSSVTMGVILVCVTALMGCLFLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYSFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------AASTA-GQNYS--MVSEFILVGFSTFPQHLLPA----FFLLFLL-MY
LFTLLGNLI-IMATVWSERGLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSNHH-TITFVACASQMFF-SFTFGF-THSFLLMIMVYDRYV-AICH
PLHYSVLMSTHTCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNVIYH-FACHVLS
-LLKLSCGKETSSVTMGVILVCVTALMGCLFLIILSYVFIVTAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASTIYLKPKGPH---STDSNT--
-LMATTYIVF-TPFL----SPIIFSLRNKEL---KNA---IKK------TFQRKFSPLN-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------PK
---FSGTHHIDLIPWDQVFMANST--TITEFLLLGFSSLG-NFQLV----LFVIFLS-LY
VIILSGNIT-IISVILLDRSLHT--PMYFFLCVLSISETFYT--VA--------------
I-LPK---MLINLLSVLR-TLSFMSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCGQLAATCIVSGFLI----SMVGTSLVFSLPFCGSNKVNH-YFCDISP
-VIRLACGD-THINELVIFIGGVVVLVVPLFFICISYGFIAHTIMRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSARY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QIA---LRK------MIGKTGFFSK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TL-GLNHS--SVSEFILVGFSTFPPHLLPA----FFLLFLL-MY
LFTLLGNLL-IMATVWSERGLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLADLLSTRR-TIAFAACTSQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTYLVAWSWAGGSII----GLVVATAVFHLTFCGPNEIHH-FLCHVPP
-LLKLACGTDVPIVALGVGLVCITALLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGLH---SQEGNT--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKLYPSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------L
LPTRQPSLSLHPGMAATM-DLNHS--SVSEFILVGFSTFPPHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCTLSISEILYT--LA--------------
I-TPR---LLADLLSTQH-TIAFGACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYSMFMSPCTCICLVAWSWAGGSVI----GLVVATAIFHLTFCGPNEIHH-FLCHVPP
-LLKLACGTDVPVVALGVGLVCITVLLGCFLLILLSYILIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VVVHYGFASIIYLKPKSLH---SQESNT--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KTA---MKK------TSLSKLYPSG-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MM-RRNHT--VVNEFVFQGFSSFQ-EYKFT----LFMVFLT-LY
LLTLTGNAI-IMIIIGIDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLASLVGSSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCAQLVWGSCNIGLLV----AIIQIASVFRAPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIVNFIISSLVIVVPMALVFISYILIISTILKITSAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKKPLA---
-------------------------------

----------------------------------------------------AVFLLLYL
ITLGTNGLI-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQRKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVVMGHGVCVGLVGVACACGFTV
AQIITTLVFHLPFHSSNQLHHFFCDISPVLKLASHRSRLSQIVIFLLGVFVLVIPLLLIL
VSYIRIISAILK-IPSSVGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPVFNPM-IYSLRNKEFKSALRRTMGQTSFPVN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KSNAT--FVTEFLFEGFSSFNWQHRLS----LFAVFLT-LY
FLTLSGNVI-IVTIIHLDHHLHT--PMYFFLAILSISDTCYT--VT--------------
I-IPR---MLSDLLNPYH-TIAFQDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGRAACVRLASGSLGIGLGM----AIVQVTSVFSLPFCDGFVIPH-FFCDVRP
-LLKLACTD-TTINEIINFVVSVCVLILPMGVVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYLKPKSQS---LLGQDR--
-LISVTYTLI-TPLL----NPLVYTLRNKEV---KDA---LYR------AIWKKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-RT--TVSTFVLRGFSSLP-DLQDL----LFVLVFF-SH
VTILAANVS-VMVAIKLSHNLHT--PMYFFLSGLSFSETCTT--MV--------------
T-LPR---MLVDLLSDSK-TISLPECATQMFF-FFGLGG-NNCFIMAAMSYDRYT-AIHS
PLHYPILMTHRICLQLMMASSVTGIVV----SFCIVLIVFNLSFCDASTIQH-FFCDIAP
-VVSLACDY-TFFQKTILLAFTAFVLVGSFILIMISYVFIVSTVVKMPSAK---------
---------------------TCSSQLTV-VCIHYGFAGFVYLRPKDS---DSFSEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QIA---LRK------VLDNVCRFFSQ
MAVRRSRHCEI------------TLSN----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFVFLGFSSFG-KHQIT----LFVVFLT-VY
VLTL-----------------------------AASSETVYT--LV--------------
I-VPR---MLSSLIFHNQ-PISLAGCATQMFF-FVILAT-NNCFLLTAMGYDRYV-AISR
PLRYTVIMSKGLCAQLVCGSFGTGLAM----AVLHVTAMFNLPFCGIV-VDH-FFCDIYP
-VMKLSCTD-TTINEIINYGVSSFVIFVPIGLIFISYVLIISSILKIASSEGWKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SLEKDL--
-LLSMT------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-SQNYS--IISEFNLFGFSAFPQHLLPI----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSISEILFT--VA--------------
T-TPR---MLADLLSTHH-SITFVACANQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSPRDCARLVACTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FFCHVLS
-LLKLACENKTSSVIMGVMLVCVTALIGCLFLNILSYVFIVAAILRIPSAEGQHKT----
-----F--------------STCVSHLTV-VVTHYSFASFIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SLIIFSLRNKEL---KNA---INK------NFYRKFCPPSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILFGFSAFPHQMLPA----LFLLYLL-MY
LFTLLGNLV-IMAAIWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLSDMLSTHR-SITFIACANQLFF-SFTFGY-THSFLLVVMGYDRYV-AICR
PLHYHALMSLQGCARLVAWSWAGGSLI----GMTLTIIIFHLTFCESNVIHH-ILCHVFS
-LLKLACGERTTFVTIAVILVCVTPLIGCLVFIILSYIFIVAAILRIPSTEGRHKT----
-----F--------------STCASHLTV-VIVHYGFASIIYLKSRGLY---SQYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---IIK------SFHRNVCQQSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTL------------------------------VMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FFCHVPP
-LLKLACGENVLEVAKGVGIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNS---MKK------IFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNY--------------TFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSISESLFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCAGQMFF-SFMFGF-THSFLLMVVGYDRYV-AICH
PLRYNVLMSPRDCARLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FVCHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIMAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVMHYSFASLIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFYRKFCTLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-L-LMCFNFGASCTASMQ-GANRT--VVTEFILVGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATIGSERSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSAHH-SISLLACASQMFF-SFTFGF-THSFLLTVMGHDRYV-AICH
PLRYNVLMNPRGCACLVGWSWAGGSVM----GLVVTTAIFQLTFCGPSEIHH-FACHVPP
-LLKLACGDEVPLVAKGMGLVCIMALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------TFFSKLY----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MW-GANHS--TVTEFILIGFSTFPH-LQLM----FFLLF-----
--------------LWSERSLHT--PMYLFLCALSISEILYT--FV--------------
I-IPR---MLADLLSTHH-SITFVACGNQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPHGCACLVAWSWIGGSVM----GMVVTTAVFQLTFCGPNEIHH-FACHMPP
-LLKLACGENVPVVAKCVGLVCITVLLGCCLLILLSYAFIVSTILRIPSAEGQHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
KILPTYTSCLAKISELHMMKINQT--VLTEFILVGFSVYP-HAQTF----LFVAFFC-LY
LPTLTGNLT-IMGLTWVDRHLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPR---MLADLLAKDR-SISSIGCGLQMCF-FLGLGG-TNCMILTLMGYDRFL-AICN
PLRYPLLMTNMVCGKLVAFAWIVGFIF----SVIETALIFRGSFCNPNLVKH-FFCHMRA
-VVRLSCLD-SDLTEFIVTVMSVSGLMGTFLVIILTYVFILSTVLKIPSGEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-VIAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------ALRYFLNSLV-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MNLPQTM
SE-MKSQSTNKVIPWKQLPLENFT--MVTEFLLLGFSNLN-KMQFV----LFGVILC-LY
LVILSGNIT-VITTICLEHSLHT--PMYFFLSVLSVSETSYT--LV--------------
V-LPK---MLLNLLSVLR-TISFTSCVAQMFF-LLGFGT-TNCLLLGVMGYDRYT-AICH
PLRYPVLMSWWICKLMATTCGISGFLV----SIFGTFLAFSLPFCNSNRINH-YFCDIAP
-VIRLACGD-PYINEAIILIAGIVVLVVPWMFICISYGFIIRTILRIPTTEGKKKA----
-----F--------------STCASHLTV-VVFHYGCASFVYLRPSSKH-T--TDKDK--
-LVTVTYTIV-TPLL----NPMVYTLRNREV---RVA---IQK------VMNWRGFSPKI
I------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-QKNVT--CWRGFVFLGFSSFG-EVQLL----LFALFLS-LY
LITLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPK---MLCGLAVGSQ-AISYAGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASFMNPTLCCQLVIASFLSGYLF----GLGMTLVIFCLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TALSELGILILSLVVLLVSFIFITISYTYILANILRIPSAKGRKKA----
-----F--------------STCASHFTV-VIIHYGCASFIYLRPKAS---YSPERDQ--
-LIAVTYTVV-TPLL----NPIVYCLRNQAV---QTA---LK-------NAFQGSLLGKG
-------------------------------

----------------------MAWVNETVVREFVFLGFSSLARMQ--WLLFIVFLLLYL
FTLATNAVI-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHGVCVALVAAACASGFAV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLAVASYHTHFSQIVIFMICALVLVIPLSLIL
VSYVHIISVIFQ-FPSTMGRYRAFSTCASHLMDVTVHY----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVNMFLLWGFSSFP-ELHNL----LFVVVLL-SH
VTIILANAF-IMVAIKLNHNLHA--PMYFFLFALSFSETCTT--MV--------------
I-LPR---LLVDLISKNK-AISLPECATQMFF-FFGLGG-NNCFILSAMSYDRYT-AIHN
PLHYPILMTQKICLHLIVASGVLGFSI----SLCIVITIFNLSFCNSNIIQH-FFCDIDP
-VVSLACNL-TFYHKVILFALTAFVLVGSFIFIMVSYVFIVTVVIKMPSAKGRYKT----
-----F--------------STCSSHFTV-VFIHYGFASFVYLRPKNS---YSFRDAT--
-LLAVTYTIL-TPLL----NPIIYSLRNKGI---QTA---LKK------DIGNIIRFFSK
MV-NKKAQKI---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TASTFFFWGFSSFP-DLQGL----LFVMIFF-SH
VTILTANLS-IMAAIKLSHNLHM--PMYFFLCGLSFSETCTT--MV--------------
I-IPR---MLVDLLSDSK-EISLLECATQMFF-FFGLGA-NNCFIMTSMSYDRYT-AIHN
PLHYSMLITRKVCFQLMMASWMFGFLV----SLCIVIIVFNLSFCDSKTIQH-FFCDIAP
-VVSLACDS-TSLHEVVIFVLCAFVLLGSFIFIMISYVFIVFIVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFASFVYLKPKNN---DSFHEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QLA---LRK------VLGNANSFIHH
LANKRTMNI----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANYT--PVREFVFQGFSNLQ-EHWLT----LFIVFSA-LY
ILTLTGNLI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-SISLECCGIQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSIIMNWRVCVILASSVCAMGFLL----SLAQAVAIFRLPFCNTL-IEH-FFCDVRP
-ILDLACMV-PVINDILTLVLSLMVITAPATFLCVSYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKPKSEN---TSDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QNA---LRK------VLGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-GQNYS--TMSEFILIGFSNFPQHLLPA----FFLLYLL-MY
LFTLLGNLL-IIVTIWSEHSLHT--PMYLFLCALSISEILFT--VA--------------
I-TPH---MLVNMLSNHR-SISFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTHDCARLVSWSWAGGSVM----GMMLTLIVFHLTFCGSNEIHH-FLCHVLS
-LLKLACGKETSSVTMGVILVCVTALMGCLFLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VIVHYGFASMIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---MKR------TFHRTFCPSSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-SQNYS--IISEFNLFGFSAFPQHLLPI----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCTLSVSEILFT--VA--------------
I-TPH---MLADLLSTHH-SITFVACANQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSPRDCAHLVACAWAGGSVM----GMMVTTIVFHLTFCGSNVIHH-FLCHVLS
-LLKLACENKTSSVIMGVMLVCVTALIGCLFLNILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFASFIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFYRKFCPPSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------IPS
H--WVFFTFSSSRYAAML-GLNYT--SVSEFILIGFSTFPQHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWRERSLHT--PMYLFLCALSTSEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFTPGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWAWGG---I----GLLVTSAIFHLTFCGSNVIHH-FLCHVFS
-LLKLACGKETASVSMAVILLCVTALMGCLFLIVLSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASLIYLKPRGAH---SMDNNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------NFRR-------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MCGFNKTT--VVTQFILVGFSSLG-ELQLL----LFVIFLL-LY
VTILVANVT-IMAVIRFSWTLHT--PMYAFLFILSFSESCYT--FV--------------
V-IPQ---LLVHLLSDTR-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLISLSGATGFSI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNKEV---KAA---LKR------VLGMPVTTKTS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANHT--ELREFVFQGFSNFP-EHHV---------------
-------L--------------------------STSETFYS--LV--------------
I-IPR---MLSSLVSPSQ-SISLEGCGTQIFF-FLGFAI-TNCLLLAVMEYDHYVVAVCN
PLRYPVIMNWRVCAILASSVCATGFSL----SLVQSVAIFRLLFCTPL-IEH-FFCDIQP
-VLDLAWAT-PMINDILTLIMSLLAITAPATFLFISYVLIISTILKITSAEGGKKT----
-----F--------------ATYASHLTV-VIIHYGCASIAYFKPNLKN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYGLRNKEV---QDA---LQR------VLGRKFFS---
-------------------------------

----------------------MEWANETLVTEFVFLSFSSLAGLQ--QLLFAVFLLVYL
FMLGTNAII-VSTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTLLMGHGVCVGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDIFPVLKLASHHSYLSQLVVFVLGVFALIIPLLLIL
VSYIRIISAILK-IPSSVGRYKTFSTCASHLIVITVHYGCASFIYLRPKSNYSTSQDTLI
SVFYTILTPLFNPM-IYSLRNKEFKSALQRTMAQTSCL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GINHS--GVSEFILIGFSTFPH-LQMV----FFLLFLL-MY
LFTLLGNLF-IMATIWSERSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGENVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLSKLYPE--
----------II-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------V-LGNFS--AGTEFILVGFSTFPH-LQVM----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCTLSTSEILYT--LA--------------
I-TPR---LLADLLSTRH-TITWAACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSVM----GLVVTTAVFHLTFCGPNEIHH-FACHVPP
-LLKLACGTDVPVVAKGVGLVCIMALLGCCLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KTA---MTK------TFLNKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MINQT--ILKEFILIGFSAYP-LVQTC----LFVVFLC-LY
MVTLAGNLA-IMGLTWVDRSLHT--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLIDKDS-RISVTGCGLQMCF-FLGLGG-TNCILLTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFIVTLMSVSGLLGTFLLILLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VLIHFGFASVVYMKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDM---KNA---FRK------IMRKTVVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MEWVN-ET--VVREFVFLGFSSLA-RLQLL----LFAIFLIL-Y
LFTLGTQAI-IISTIVLDRALHT--PMYFFLSVLSCSETWYT--FV--------------
I-IPK---MLVDLL-----TISFLGCAIQMFT-FLFLGC-SHSFLLAAMGYDRYV-AI--
-----------------------CFTV----SLVTTSFVFHLPFHSSNQLHH--FCDISP
-VLKPTPHH-SCLSQLVIFMLGVFVLVIPLLLMSH--VHI----ISSPSSVGRYKA----
-----F--------------STC-----------------AHLIVATN---LSSGQDT--
-LISASYTIL-TPLF----NPMIYSLRNKDF---NAA---PRR------TLGQNLYPGNQ
RTNLTKYSWL----YVPEKCILPHIFFLI--

----------------------MERVNETVVREFIFLGFSSLARLL--QLLFVIFLLLYL
FTLGTNAIF-ISTIVLDRALHTPMYSFLAIFSCSETCYTFVIVSKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCYHSFLLAAMGYDCYMAICNPWHYSVLMGHGMCLGLVAADCACGFTV
PLGTTFLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGLSQLVIFMLGIFAL--------
----------------------TLSTCPSHLIVVTVHYGCASFIYLRPKTNYSSREDTLI
SVSYTILTPLTISQTLYPLN----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVSTFLLWGFSSFP-DLQTL----LFVMIFF-SH
VTILAANVS-VMVAIRLSHNLHT--PMYFFLCGLSFSETCTT--MA--------------
I-IPR---MLVDLLADCK-TISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYI-AIHN
PLHYPILMTHKICFQLLMASWMAGFLV----SLCIVIIVFNLSFCDSNIIQH-FFCDISP
-VVCLACDY-TSHQEMAIFVLSAFVLVGSFVFIMMSYVFIVSTVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLGRTDRFIPQ
MVNKRTPHS----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-ESNVT--CWQGFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTVCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGSLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------F
LL-CFPL------FNHLMNEQNFT--MVTEFLLLGFSKLQ-ELQLV----LFAVFFC-LY
IIILCGNIT-IVTVILLENNLHT--PMYFFLGVLSVSETCYT--FV--------------
I-LPK---TLLNLLSMLR-AISFISCAIQMFL-FLSFAI-NNCLLLGVMGYDRYA-AICQ
PLRYPILMNWRTCRLLAATCGVSGSLI----SMIGTTLVFILPFCNCNKINH-YFCDISP
-LIHIACGD-TYLNEMIIFICGVLVLVVPLICVCVSYGFIVSTILKIPSTEGKQKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSSKV-T--SDKDQ--
-LVTVIYTVI-TPLL----NPMVYSLRNRDV---QAA---IWK------VISRGKFS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----NLLSIFFNFLKFRTMRINQT--FLEEFIFFGFSAYL-EWQIV----LFVCFFF-VY
LLTLTGNLV-IMALTWVDHALHI--PMYLFLAALSFSETCYT--LA--------------
I-IPK---MLIDLLAKNR-SISIPGCALQMFF-FLGLGG-TNCIILTVMGFDRFL-AICH
PLRYPTLMTNKACGQLVASAWIGGFFV----SSTETTLIFWGSFCGPNLIKQ-FFCHMRA
-VAKLSCLN-SYLKEIIVTVISESGLLGTFLFIILTYVFILSTVLKIPSAEGRKKA----
-----F--------------STCASHLTV-VIIHFGFAAIVYLKPEAQ-----EGDDS--
-LITVPYTVV-TPFL----SPIIFTLRNKDM---KNS---LKR------VLDKKVALTR-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-RELNIYLLFLSHFRHATMKANQT--VLKDFILVGFSSYP-HMRTF----LFVLFFG-LY
LLTLTGNLA-ILGLTWADRSLHT--PMYLFLRALSFSETCYT--LT--------------
I-IPK---MLADLLTEKR-SISVPGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICH
PLRYPLLMTNVVCGQLVVSAWAGGFLI----SVTETALIFGGSFCTPNLIHH-FFCHMRA
-VVRLSCLD-SDLTELVVTMISVSALTGTFLFIVITYVFILSTVFRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHFGFAAIVYLKPEGS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNRDM---KNA---FRK------LLACRKPETGS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------QQAGNGTE--LVSEFVLVGFSSVP-HLRPT----LFALFLL-TY
LVTLGGNAT-IIALIHADRSLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLLRSQ-AISIAGCRAQMFF-FLGLGC-SHCFLLTLMGYDRSV-AICR
PLRYPLLMRPSVCVGLGALVFGAGFSV----ALTETCLVFSAPFCGGPRVEH-FFCDIGP
-VLRLSCAQ-SARRALAIFFLSVLVVLVSFLLILLSYAFIVAAVVRMPSAASRRKA----
-----F--------------STCAAHLTV-VVVHFGCASIIYLRPDSGG-H--PARDR--
-LVAVFYTVV-TPLL----NP---------------------------------------
-------------------------------

----------------------MEWVNETWVREFVFLGFSALASLQ--RLLFMVFLLVYL
FTLGTNAII-MSTIVLDRALHTPMYFFLSVLSCFETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYGRYVAICNPLRYTVLMGHGVCLGLVAAACACGFTV
SLVITSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSRLSQLVIFMLGVLVLVIPLLLIL
VSYVRIISVILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRTMSKTWF-SLN-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------RRMDN-HT--TVSTFLLWGFSSFP-DLQDL----LFVMVFF-SH
VTILAANVA-VMVAVKLNHSLHI--PMYFFLCGLFFSETCTA--MV--------------
I-IPR---MLVDLLSDSK-SISVFECATQMFF-FFGLSG-NNCFIMAAMSYDRYT-AIHN
PLHYSVLMTRKICFQLMMAAWLVGFLV----SMCIVTIVFNLSFCDSNTIQH-FFCDISP
-VVCLACDY-TLSYEMAIFVLSAFVLVGSFILIMISYVFIGSIVMKMPSAEGRYKA----
-----F--------------STCSSHLTV-VCTHYGFAGFVYLRPKSS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QIA---LRK------IVDSASRFI--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------LLMGQQ-CLNQS--RITEFILVGFSSLG-DLQIL----LFFIFLL-VY
LTTLMANVT-IMTVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-IPK---MLTNLLSTDK-TISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYMLIVSRATCIQLVLASALCGFMI----SVIVNILVFSLPFCASNRVNH-FFCDISP
-VIKLGCTD-TNMKEMIIFFLSILVLLVPFVLIFISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCISHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPML----NPLVYTLRNKEV---KTA---LRR------VLSRYSLPKSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-RLNFT--AVTQFTFESFSSFEWHHRLI----LFVVFLV-LY
LLTLASNAI-ILTVIRLNRQLHT--PMYFFLGMLSISETCYT--MA--------------
I-IPQ---MLSSLLRPQQ-AISIPGCATQLFF-YLTFGV-NNCFLLTAMGYDRYV-AICN
PLRYSLIMGKKACLQLASGSWIIGLST----AIIQVSSVFTLPFCDASVISH-FFCDVRP
-LMKLACAD-TTSKEFITLLISLCVLVLPMILIFISYVLIVTTILRMASAEGWKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-IPLL----NPVVYSLRNKEV---KDG---LLR------VLGRKPLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWFECRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCGPVRR------GG-GPS-FFMVMAMIVTG-AICH
RTAYNVLMSPL------------------------TVPLFHLTFCGLMIHH--SCLSLLS
-LLKLTCGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIVAAILRIPSPEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFASLIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFYRKFCTLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VTAENIT--MVTEFFLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IVSVIRQDQSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAQ-TICFICCAIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMNWQVCGKLATACGIGGFLA----SLTIANLVFSLPFCGANKINH-YFCDISP
-VIHLACTN-TDVHEFVIFICGVLVLVVPFLFICVSYSCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASYIYLRPTANY-V--SSKDR--
-LVTVAYTIV-TPLL----NPMVYSLRNKDV---QVA---LRK------VLGKKSICTIV
-------------------------------

----------------------MERVNETLVAEFVFLGFSSPARMQ--LLLFIVFLLLYL
FTLGTNAII-ISTIVLDRALHNPMYFFLAVLSYSETCYTFVIVPKMLADLLAQKKTITFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYMAICNPLQYTVLMGHGMCVGLVAAACACGFTV
SLVTTSLVFYLPFHSSNQLHHFFCDISPVLKLASHHSRLSQLVIFMLGVCVLVIPLLLIL
VSYIHIISAILK-ISTSAGRYKTFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDILI
SVSYTILTPLFNPM-IYSLRNKEFKSAFRRVMGQT-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKANQT--VLKEFILVGFSLYP-HVRTF----LFVLFSG-LY
LLTLTGNLA-ILGLTWADRSLHT--PMYLFLRALSFSETCYT--LT--------------
I-IPK---MLADLLTEKR-SISVPGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-L---
----------------VVSAWAGGFLI----SVTETALIFGGSFCTPNLIHH-FFCHMRA
-VVRLSCLD-SDLTELLVTMISVSGLTGTFLLIVTTYVFILSTVFRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHFGFAAIVYLKPEGS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNRDM---KNA---FRK------LLAKRSFWNT-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--ILLFFKFKNIMCDLMK-KENHS--LVSVFIFQGFSSFH-EHKFT----LFVVFLT-LY
IFTLAGNVI-IVGIISIDHHLHT--PMYFFLSMLSGSETVYT--LV--------------
I-IPR---MLFNLIGQSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMSKRVCMQLVWGACSIGLIV----AMIQVSAVFRLPFCTTK-VPH-FFCDIRP
-VMKLSCID-TTVNEILTMIISVLVILIPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LIAVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LCR------AIGQKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GENYS--SISEFILFGFSAFPQQMLPA----LFLLYLL-MY
LFTLLGNLL-IMAAVWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLADLMSTHR-SITFIACANQLFF-SFTFGY-THSFLLMVMGYDRYV-AICR
PLHYHVLMNLQGCARLVAWSWVGGSLI----GMTVTLIIFHLTFCESNVIHH-FLCHVFS
-LLKLACGERATSVTIVVILVCVTPLIGCLVLIVLSYIFIVAAILRISSTEGRHKT----
-----F--------------STCASHLTV-VVVHYGFASIIYLKSRGPH---SLYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------SFHRNFCQRSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MPVA-GPNST--FVTEFLFEGFSSFGWQHRLV----FFVVFLT-LY
LLTLSGNVV-IVTVIRLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPC---MLSGLLNPQK-TISFQDCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKRACVQLVCGSLGIGLSM----AIVQVTSVFGLPFCDGFVISH-FFCDVRP
-LLKLACTN-TTVNEIINFVVSVFVLVLPMALVFISYVLIIATILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LCR------AL---------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHS--SVSEFILIGFSPFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMTTIWGERSLHT--PMYLFLCALSISEILYT--FA--------------
I-VPR---MLADLLSTHR-SIAFVACASQMYF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLVVTMAIFHLPFCGPNEVHH-LGCHALP
-LLKLACGGNVSTVALGVGLVCITALLGCCLLILLSYASIIATILRIPSAEGRQKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKSKGPQ---SLEGDT--
-LMGVTYTVL-TPFL----SPIIFSLRNKEL---KSA---MKR------TVLSRLLLQSS
R---R-GW-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------THFKGFFL
TLSPHLSQKI---MYFLKEWTNNT--LVREFVFLGFSALA-GLQQL----LFAVFLL-FY
LLTLGTDVI-IISTIVLDRALHT--PMYFFLAVLSSSETCYT--FV--------------
I-VPK---MLVDLLSLKK-TISFLGCAIQMFT-FLFLGCXTNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLVSLSGVTGFFI----ALVATNLICDMPFCGPNRINH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLAMPVATK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-REINVCYCFFQILDVQTMKINQT--IVKEFILVGFSAYP-HVQTF----LFVVFFC-LY
LFTLAGNLT-IMGLTWVDRSLHT--PMYIFLSSLSFSETCYT--LS--------------
I-IPK---MLTDLLAKNR-SISVTGCGLQMCF-FLGLGG-TNCIILTLMGYDRYL-AICN
PLRYPLVMTNIICGHLVASAWVGGFLI----SLTETALVFKNYFCKPNFVKH-FFCHMRA
-VVRLSCED-SDLTEFIITVIPVSGLLGTFLLIILTYVFVLSTVFRIPSSEGKQKA----
-----F--------------STCASHLTV-VIIHFGFSTIVYLKPEAS-----G-DDT--
-LIAIPYTVI-TPFL----SPMIFSLRNKDM---KNA---FRK------IMEKTVALDK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ME-RDNHT--WVSEFTFQGFSSFR-EHQLT----LFVVFLA-LY
AFTLAGNVV-IVTIISVDRHLHM--PMYFFLSMLSASETTYT--LV--------------
I-IPK---MLCNLLGLSR-PISLAGCATQMFF-FLTLAI-NNCFLLMAMGYDRYV-AICN
PLRYTVLMNKTVCIQLVGGACSIGLIV----ATTQVLAVFRLPFCATK-VAH-FFCDIRP
-VMKLSCVD-TTANEILTVVISVLVILVPMGLVFISYVLIISTILKIPSAQGRKKA----
-----F--------------ATCASHLTVVVIVHYGCASIAYLKPKSEN---SRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------ATGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VAAML-GLNHS--FVSEFILIGFSTFPH-LQMV----FFLLFLL-MY
LFTLLGNLF-IMATIWSERSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLVDLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWSWVGGSFM----GTVVTTAIFNLTFCGSNEIHH-FFCHVPP
-LLKLACGGNVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVT---MKK------AFLNKLFLQ--
----------N--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVILAENVT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LAILSENVT-IISVIRLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGLMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPVVYSLRNKDV---QLA---IRK------VLGKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GLNYT--WASEFILIGFSTFPQQLLPV----FFLLFLL-MY
LFTLLGNLL-IMVTIWGERSLHT--PMYLFLCALSISEILYT--LA--------------
I-IPR---MLADLLSAHR-SIAFVACASQMFF-SFTFGF-THSLLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGLAV----GLVVTTSIFHLTFCGPNEIQH-FLCHVPP
-LLKLACGNNVPTTALGVGLVCITALLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLIV-VIVH--------------------------
------------------------------------------------------------
-------------------------------

----------------------MECVNDTVVREFVFLGFSSLAELQ--LLLFAIFLSLYL
FTLSTNAVI-VSTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLARKKSISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICHPLRYTVLMGHRVCVGLVAAACVCGFTV
AQVITSLVFRLPFRSSNQLHHFFCDISPVLQLASHHPHSTQITIFLLCALVLVIPLFLIL
VSYIHIISTILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSSYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKDFKSALHRVIGRTVTLRQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ET
LP-LSSPLSPTPGMTAML-GLNHS--SVSEFILIGFSPFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-ILTTIWGERSLHT--PMYLFLCALSISEILYT--FA--------------
I-VPR---MLADLLSTHR-SIAFVACASQMYF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVL----GLVVTMAIFHLPFCGPNEIHH-FACHALP
-LLKLACGSNVSTVALGLGLVCITALLGCCLLILLSYASIIATILRIPSAEGRQKA----
-----F--------------STCASHLTV-VVVHYGFASVVFLKSKGPQ---SLEGDT--
-LMAVTYTVL-TPFL----SPIIFSLRNKEL---KSA---VKK------TFFPKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---LRVDCWLLEISDTPNMKPNQT--ALWEFILVGFSTYP-HLQSF----LFVLFFC-LY
LLTLTGNLA-ILGLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLAQSR-SISVTGCGLQMYF-FLGLGG-TNCLILTLMGYDRFL-AICK
PLQYPLLMTNAGCGQLVASAWAGGFCF----SLFITALIFRGAFCSPNLIKV-FFCHMMA
-VARLSCVD-SDLTETIVTVVSVTGLLGSLLLITLTYVFILSSVLRIPSSQGRQKA----
-----F--------------STCASHLTV-VIVHYGFASIVYLKPKG-------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRGFNSST--VVTHFVLVGFSSLG-ELQLL----LFVLFLL-LY
LTILVANVT-IMAVIRVSRTLHS--PMYGFLFILSFSESCYT--LV--------------
I-IPQ---LLAHLLSATK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYLLIMNRRLGLGLVSLSGVTGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-TQVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCVSHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVSYTVV-TPLL----NPLVYSLRNQEV---KSA---LRR------VMTMPKATKMS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MR-RQNQS--MITEFILIGFSNLG-DLQIL----LFFLFLL-VY
LTTLMANAT-IMTVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTSQ-TISFPACAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLVVSRATCVQLVLASSCCGFLI----SVVVNVLVFSVPFCASNRINH-FFCDIFP
-VIKLGCTD-TNVKEMVIFFLSILVLLVPLVLIFISYVFIVSTILKIASAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SEKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LSK------VLSRYSFPKT-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KQNHT--LVCEFTFQGFSNFR-EHQLT----LFVVFLA-LY
ILTLAGNVI-IVTIISFDRHLHT--PMYFFLSTLSASETVYT--LV--------------
I-IPR---MLFNLVGLCQ-HISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCLQLVWGACSIGLIV----AMIQVSAVFRLPFCTAK-VAH-FFCDIRP
-VMKLSCID-TTANEILTLIISVLVILIPMSLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VVIHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LWR------AMGKKLP----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KQNHT--LVSEFTFQGFSNFH-EHELT----LFVVFLA-LY
ILTLAGNII-IVTIISLDRHLHI--PMYFFLSMLSASETVYT--LV--------------
I-IPR---MLFNLVGLSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCLQLVWGAFSIGLIV----AMIQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTANEILTLIISVLVILIPMSLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VVVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LWR------AMGNKLP----
-------------------------------

----------------------MERSNETNVSEFVFLGFSALAEFQ--QLLFAVFLFLYL
FTLGTNAVI-LSTILLERALHTPMYFFLGILSSFETCYTFVIVPKMLVDLLAQRKTISFV
GCAIQMLTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHGTCMGLVAAACACGFTV
ALVTTSLVFHLPFHSSNQLHHFFCDISPVLQLASHHTLLSQMVIFMLGVFVLVIPLLLIL
ASYVRIISAILK-IPSIVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKTNYTSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKAALWRALGQNLCSKH--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----IICCFFQISDMQTMKVNQT--VLKEFILVGFSVYP-HVQAF----LFVVFLC-LY
LLTLTGNLA-IMGLTWVDRSLHT--PMYLFLGALSFSETCYT--LT--------------
I-IPK---MLADLLTENK-SISVMGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNGVCGQLVASAWGGGFLI----SLIETALIFRGSFCSPNLVKH-FFCHMRT
-VARLACID-SNLTESIVTMISVSGLMGTFLLIIITYVFILSTVFRIPSAKGKQKA----
-----F--------------STCASHLTV-VIIHFGFAAIVYMKPETS-----GGDDT--
-LMSVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGKRSFLNK-
-------------------------------

----------------------MERVNETVVREFIFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYIAICNPLHYSVLMGHGVCMGLVAAACACGFTV
AQIITSLVFHLPFYSSNQLHHFFCDIAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHILSAILQ-FPSTLGRCKAFSTCVSHLIIVTVHYSCASFIYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCKIVRRTISLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KLNST--FVTEFLFEGFSSFRRQHKLV----FFVVFLT-LY
LLTLSGNVI-IMTIIRLDHHLHT--PMYFFLCMLSISETCYT--VA--------------
I-IPH---MLSGLLNPHQ-PIATQSCATQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRYSVIMGKRACIQLASGSLGIGLGM----AIVQVTSVFGLPFCDAFVISH-FFCDVRH
-LLKLACTD-TTVNEIINFVVSVCVLVLPMGLVFISYVLIISTILKIASAEGQKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTHH-SPTE----PCCVQP---EEQ---G-G---QRC------SAQSRGAKNSV
SLMKR-------------GCEGFSFAFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MTLKVCFQLMMASAVVGFLV----SLCIVIIVFNLSFWDSNTIRH-FFCDIAP
-IASLACSY-TFFQKMVLLAFTAFVLVGSFILIMISYVFIVSLVVKMPSAKGRRKA----
-----F--------------STCSSHFTV-VSVHYGFACFVYLRPKNSD-SDSFSEDT--
-LMAVTYTVL-TPLL----NPIVHSLQNKEM---QVA---PRK------VLGSIIFNK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSGFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSNSEILFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCAGQMFF-SFMFGF-THSFLLMAMGYDRYV-AICH
PLRYNVLMSPHDCAHLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FVCHVLS
-LLKLACGNKTSSAIMGVMLVCVTALKGCLFLIILSYVFIMAATLRIPSAEGRQKT----
-----F--------------STCVSHLTV-VVVHYSFASLIYLKPKGLH---SMYSDT--
-LMATTYTVF-TSFL----SPIIFSLRNKKL---KNA---INK------NFHRKFCLLSS
C---MPIWW----------------------

----------------------MEQINETAVTEFIFLGFSSLAGLQ--RLLFLVFLLLYL
FTLSTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLMAQKKTISFL
GCAVQMSIFLFLGCSHSFLLAVMGYDRYVAICNPLRYTVIMGPGVCRGLVP-ACVCGFTA
LTTSL-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GINHS--GVSEFILIGFSTFPH-LQMV----FFLLFLL-MY
LFTLLGNLF-IMATIWSERSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGENVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLSKLYPE--
----------II-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTTFLLWGFSSFP-ELQNL----LFVVIFL-SH
MTILIANAS-IMVAIKLNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---ILVDLLSESK-VISLPECATQMFF-FFGLAG-NNCFIMAAMSYDRYT-AIHS
PLHYHIFMTQKVCFQLIMASCVIGFLC----SLSITFTIFNLSFCDSNTIQH-FFCDISP
-LVYLACDY-TAHHAMIIFMLSAFVLVGSFVLIMISYIFIVFLVVKMPSAQGRHKA----
-----F--------------STCSSHLTV-VTMHYGFACFVYLIPKNS---GSFHEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLYSVNKILPC
LAITNPEHLRTT-IKH---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-TENCT--LVSEFVFQGFSSFR-EHQLT----LFVVFFA-LY
ILTLAGNII-IVTIISLDRHLHT--PMYFFLSMLSASETVYT--LV--------------
I-IPR---MLLSLVVLSQ-PISLAGCATQMFF-FVMLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCTQLVWGAFSIGLIV----AVTQVSAVFRLPFCITK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLVISVLVILIPMGLVFISYILIISTILKIATAEGRKKA----
-----F--------------ATCASHLIV-VIVHYGCASIAYLKPKSEN---TMGEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LQR------AIGRKLS----
-------------------------------

----------------------MECVNETVVREFVFLGFSALAELQ--LLLFAVFLFLYL
FTLSTNAVI-VSTIVLDRALHMPMYFFLSVLSCSETCYTFVIVPKMLVDLLARRKSISFL
GCAIQMFAFLFLGCSHSFLLAAMGYDRHVAICHPLRYTVLMGHRVCVGLVAAASVCGFTV
AQIITSLVFHLPFCSSNQLHHFFCDISPILQLASHHPHSTQITIFLLCALVLVIPLLLIL
VSYVHIISAILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSNYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKEFRSALHRVIGRTVTLRQC-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MERGNETVVKEFAFLGFSSLAGLQ--RLLFIVFLLLYL
FTLGTNAVI-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLIDLLAQKKTISFL
GCVIQMFAFLFLVCSHSFLLAAMGYDRYVAICNPLRYTVLMGHAVCMGLVATACASGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSLLSQMIIFTLGVFVLVIPLLLIL
VSYIHIISAILK-IPSSVGRHKAFSTCASHLIVITVHYGCASFIYLRPKSNYSSSRDSLI
SVSYTILTPLFNPM-IYSLRNKEFKSALR-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LLFCIRPGGHSMK-IENYT--VILEFTFQGFSSFR-EHQLT----LFVVFLA-LY
ILTLVGNII-IVTVIQIDSHLHT--PMYFFLSMLSTSETIYT--LV--------------
I-LPR---MLSSLVGMSQ-SISLAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYTISMNKRVCAQLVWGACSIGLIT----AMTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCTX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-------------------------
----XXXXXX-XXXX----XXXXXXXRNKEV---KDA---LRR------AGRKL------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------KTQHRRVI
LI-PQMLVITKVIPWKQLPIENLT--MVTEFLLLGFSDLQ-EMQFV----LFAVILC-LY
LLILSGNIT-IITTVRLEHSLHT--PMYFFLAVLSFSETFYT--FT--------------
I-LPK---MLLNLLSVLR-TISFISCATQMFF-FLGFAI-NNSLLLGLMGYDRFT-AICY
PLRYPVLMSWGICKLMAATCAVTGFVI----SLVSIFLVFSLPFCNSNRINH-YFCDVAP
-VIHLACGD-FSINEMIIFIFGVVVLIVPLTLICISYGFIVRTILKIPSTEGKKKA----
-----F--------------STCASHLTV-VVVHYGCASFVYLRPSSKY-T--FSKDR--
-LVTVTYTVI-TPLL----NPLVYSLRNKDV---QMA---IRK------VINWRGLSP--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MPKPN-ST--AVTEFLFEGFSSFG-WQHRL----IFFVVFLTLY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLFGLLNPYQ-CISIQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYA-AICN
PLRYSVTMGKKSCAFLASGSLGIGMGM----AIIQVTSVFGLPYCDA--FVS-FFCXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX-XX--XXXXXXXXXXXXXXXXXXX----
-----X--------------XXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXDR--
-LISVTYTHH-SPAE----PRRVHTEEQGSQRCSTKS---YRA--------ESPILLIRR
CG-----------------CLLFVFMTMG--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNAT--FWTGFVFLGFSSFG-ELQPL----LFALFLS-LY
LVTLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSSLVRGRQ-DISYVGCAVQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMNPSLCAQLVGTSFLSGYLF----GLGMTLVIFHLPFCRSHEIQH-FFCDTPP
-VLSLACGD-TSLSELGILLLSLLVLLVSFSFIAVSYTYILAAILRIPSTEGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKTI---YSLKRDQ--
-LIAVTYTVV-TPLL----NPIIYSLRNRAV---QTA---LR-------NAFRRRLLSK-
-------------------------------

----------------------MERVNETVVREFVFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYIAICNPLRYSVLMGHGVCMGLVAAACACGFTV
AQIITSLVFHLPFYSSNQLHHFFCDIAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHILSAILQ-FPSTLGRCKAFSTCVSHFIIVTVHYGCASFIYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCKIVRRTISLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVSEFIFLGFSSFG-KHQIT----LFVVFLT-VY
ILTLVANII-IVTIICIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLLSLIFHNQ-PISLAGCATQMFF-FVILAT-NNCFLLTAMGYDRYV-AICR
PLRYTVIMSKGLCAQLVCGSFGIGPTM----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCTD-TTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKT----
-----F--------------ATCASHLTV-VIVHCGCASIAYLKLKSES---SIEKDL--
-VLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLCFRFGNQSMK-TENFT--LITDFVFQGFSSFR-EQQIT----LFGVFLA-LY
ILTLAGNTI-IVTIIRIDHHLNA--PMNFFLSMLSTSETVYT--LV--------------
I-LPR---ILSSLVGMNQ-PISLAGCATRIFF-FVTFGI-TNCFLPTAMGYDCYV-AICN
PLRYAIIMNKRVHIQLVLGACSIGLIV----AITQVTSVCRLPCCARK-VSH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVE----G-R-K
-K-A-F-A-------------TL-------------------------------------
-----TYTVI-TPLL----NPVVYTLRNKEV---KDA---LSR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AINQT--TLKEFILIGFSAYP-HVQTF----LFGVFFC-LY
ILTLAGNLT-IMGLTWVDRSLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPR---MLVDLLNNDR-HISVAGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWAGGFLI----SLIETALIFRVSFCIPNLIRH-FFCHMRA
-VVRLSCID-SDLTEFIVTLMSVSGLLGTFLLISLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFSLRNKDM---KAA---FRK------VMRKTIVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KKNST--VVAEFLFEGFSSFDWQHRLG----FFIVFLT-LY
LLTLSGNMI-IVTIIRLDRHLHT--PMYFFLSMLSISETFYT--IA--------------
I-IPR---MLAGLLNPYQ-AIDIQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKACILLASGSLGIGLSM----AIVQVTSVFGLPFCDGFVIAH-FFCDVRP
-LLKLACTD-TTINEIINFIVSVCVLVLPMSLVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQT---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LRK------AIGRRPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------METRDIKNS-FR--VESKEFGPQYEVYR-DSHPI----RMLLFIQSPS
LDFSAANLS-IMVAINFSHNLHT--PMYYFLCGLSLSETCTS--MV--------------
V-LPR---MLVDLLSESK-TISLSECATQMFF-FLGLAA-NNCFIMASMSYDRYI-AIHN
PLQYSILMTQKSCFQFMMASWIVGFLV----SLCIILTVFSLSFCDSNIIQH-FFCDISP
-VISLACDY-TSHHKMAIFGFSAFVLVGSFTLIMISYVFIVSVVMKMPSVKGRYKA----
-----F--------------STCSSHLTV-VFIHYGFACFVYLRPKNR---DSFGEDM--
-LMSVTYTVL-TPLL----NPIVYSLRNKEM---QVA---LRK------VLDSVTRFFPQ
LTKKEPEHLNLL-SIDK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANHS--AVTEFILIGFTTFPH-LQLM----FFFLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--LA--------------
I-IPR---MLADLLSAHH-SIPLVACANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRACACLVAWSWIGGSVM----GMVVTTAIFHLTFCGPNEIHH-FACHVPP
-LLKLACGENVPVVAKGVGLVCITALLGCCLLILLSYAFIVSTILRIPSAEGRHKA----
-----F--------------STCVSHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---IKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANAS--MVTEFVLVGFSAFPHLQ-LP----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLATRH-IITRGACAAQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLHYHVLMSPRGCGCLVGGSWAGGAVL----GSVVTAAVFSLLFCGPNQVHH-FACHVPP
-LLKLACGHEVPWVALGVGLLCISTLLGCFLLIVLSYTFIVATILKIPSAEGRRKA----
-----F--------------STCASHLTV-VVVHYGFASVIYFKPKGPQ---SLEGDT--
-LMGFTYTVL-TPFL----SPIIFSLRNKEL---KLA---IHK------TFFSRP-----
-------------------------------

----------------------MEWVNETTVREFVFLGFSSLAGLQ--QLLFFIFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLGVLSCFETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACAGGFTV
SLVTTSLIFHLPFHSSNHLHHFFCDISPVLKLASHHSHLSQLVIFMLGVFALVIPLLLIL
VSYIHIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYASSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRAIVQTLY-PVN-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EITEFIFLGFSGFH-EHQIT----LFVFFLI-LY
TLTLAGNAI-IVTIIHIDQRLHT--PMYFFLSMLASSETVYT--LV--------------
I-IPR---MLSSLIAQNK-PISLSGCTTQMFF-FVTLAI-NNCFLLTVMGYDRYV-AICN
PLRYTNIMSKWVCIQLVCGAFSIGLAM----AVVQVTSIFTLPFCHRV-VGH-FFCDILP
-VMKLSCID-TTINEIINFVVSLFVILVPMGLVFISYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---SLEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------TVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENLT--VVNEFVFQGFSSFR-EHKLI----LFVFFLI-LY
LLTLASNAI-IVIIISIDRYLHT--PMYFFLSMLSTSETLYT--LV--------------
I-VPQ---MLSSLVGLSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYLVIMNKKICAQLVWGACSIGMFV----AIIQISSVFRQPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTVHDIINFIISSMVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCGSHLTV-VIVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTIF-TPLL----NPVVYTLRNKDV---KDA---LYR------AIGKKRLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------VIPWKQLPLENFT--MVTEFLLLGFSNLN-KMQFV----LFGVILC-LY
LIILSGNIT-VITTICLEHSLHT--PMYFFLSVLSVSETFYT--FV--------------
I-LPK---MLLNLLSVLR-TISFTSCAVQMFF-FLGFAT-TNCLLLGVMGYDRYT-AICH
PLRYPVLMSWWICKLMATTCGVSGFLF----SMIGTFLVFTLPFCNSNKINH-YFCDIAP
-VIRLACGD-PYINEAIIFFGGVVALVVPWMFICITYGFIIRTILRIPSTEGKKKA----
-----F--------------STCASHLTV-VVVHYGCASFVYLRPSSRH-T--SDKDK--
-LVTVTYTIF-TPLL----NPMVYTLRNREV---RVA---IQK------VMNWRGFSPKV
I------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANCT--EVREFVFQGFSNFQ-EHQLT----LFIIFFA-LY
ILTLTGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFGI-TNCFLLAVMGYDRYV-AICN
PLRYSVIMNWRVCVILASSVCATGFLL----SLVQALAIFRLPFCNTL-IKH-FFCDVRP
-ILDLACTV-PVINQVLTLVLTLMVLTAPAIFLFVSYALIISTILKIASSDGWKKT----
-----F--------------ATCSSHLTV-VVIHYGCASIVYFKPKSEN---SKDQDQ--
-LLSVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLCRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MGLNDCC----------------------
----------YFFQISNMKNN-QT--IIKEFIFVGFSHYP-DV-QI----LLFVIFFFLY
LVTLLGNMT-IMGLTWVDRDLHT--PMYIFLSALSFSETCYT--LS--------------
I-IPK---MLSDLLANNR-SISAIGCGLQMCF-FLGLGG-TNCVLLTLMGYDRFL-AICN
PLRYPQLMTNVVCKQLVACAWVRGFFV----SVTETAXXXXXXXXXX--XXX-XXXXXXX
XXXXXXXXX-XXXX-XXXXXXXXXXXXXXXXX-XX--XXXXXXXXXXXXXXXXXXX----
-----X--------------XXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXX--
-XXXXPYTVI-TPFL----SPLIFSLRNKSM---KNA---FRK------VLEKTIAFNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MLH--SVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWREHSLHT--PMYLFLCALSTSEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFTFGF-THSFLLTVMGYDHYV-AICH
PLRYNVLMSPRGCACLVVWSWAGGSVM----GLVVTSIIFHLPFCGPNVIHH-FFCHVPP
-LVKLACGTEVQIVAMGVGLVCIAALLGCGLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTAL-TPFL----SPIIFSLRNKEL---KEA---VKK------TFLSKLFLHRS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LSMANSS--FVTEFLLLGFSSLG-ELQLV----LFVAFLS-LY
LIILSGNIT-IISVIRLDHSLHT--PMYFFLGILSTSEIFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFISCATQMFF-FLGFAV-SNCLLLGVMGYDRYA-AICQ
PLHYALLMSWRVCGQLAAACIVSGFLI----SLVGTTLVFSLPFCGPNKVNH-YFCDISP
-VIRLACAE-TYVNELIIFTCGVLVLVVPLIFICISYSFIVHTIMKIPSAEGKRKA----
-----F--------------STCASHLIV-VIVHYGCASFVYLRPSSKY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IQK------VIGKTGFSFKT
L------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MSTGSSCSQI
ID-CVTDYDALVNLWDHVNPSNFS--SVTEFLLLGFSSLG-KIQLI----LFALFLC-LY
MLILSGNIT-IVTVIRQDRSLHI--PMYFFLGVLSVSETCYT--LV--------------
I-LPK---MLINLLSLLR-TISFTNCAIQMFF-FLGFAV-TNCMLLGVMGYDRYV-AICH
PLRYPVLMRWQVCGLLAAACAGAGFLF----SLTGSLLVFELPFCGPNKINH-YFCDISP
-VIRLACTD-TSVNELLIFIGGVLALMVPLTFICISYGFIVRTILRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSAKY-S--SSKDR--
-LVTVTYTVV-TPLL----NPMVYSFRNKDV---QVA---IRK------VLGRVRFYPKA
L------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LEILTCCFFQISDIQMTWINQT--ILKEFILVGFSLYP-DIQVL----IFVVFFC-LY
LLTLMGNIA-IMSLTWVDRALHI--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLADLLAKKR-SISVVGCALQMCF-FLGLGG-THTIIFTLMGYDRFL-AICS
PLRYPLLMTNMACGQLLASAWAGGFFI----SLIETSLIFRGFFCSPNLVKH-FFCHMQA
-VVKLSCQD-SDFTEFIVTVISVSGLLGTFLLIILTYIFILSTIFRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAIPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGKIVALDK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------C
LTTLMASVT-I------------------------MTEICYT--F---------------
-----------------P-TLSFSGYATQQYY-FVGLAC--TNHFLVP-----------P
AWGWFFT------------STLCGFLI----SVVVNVLVFSVPFCASNRINH-FFCDISP
-VIKLGCTD-TNQKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSVEGQHKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSL---YSSDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKAG---KTS---LRK------VLSRYLFAKTL
---RMS-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTMFLLWGFSSFP-ELQHL----LFTVILL-SH
VTILLANAS-IMVAIKLSQNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSESK-AISLLECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLHYHILMTQKVCVQLVMVSCVVGFLC----SLGITFTIFNLSFCDSNNIQH-FFCDISA
-LVHLACNY-TVHHSMIIFMISAFVLMGSFVLIMTSYIFIVSLVVKMPSAQGRYKA----
-----F--------------STCSSHLTV-VSMHYGFACFVYLIPKNS---DSFSEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VYYTVLTIF-C
LAWQVK---RTA-IEQ---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MN-IGNHT--VVSEFVLQGFSSFH-EHKLT----LFVVFLT-LY
LFTLAGNVI-IVTIISIDRHLHT--PMYFFLAVLSTSETVYT--LV--------------
V-VPR---MLSSLVGLSQ-PISLVGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCAQLGWGACSIGLLV----ATIQISCVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCVD-TTVHDIINVIVSSLVIVVPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VVVHYGCASTAYLKPKSEN---TQDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LLR------VIGKKPLG---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQGFNRTT--TVTQFILVGFSSLK-ELQLL----LFVIFLL-LY
LTILLANAT-IMAVIRFSHTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLIHLLSATK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLISLSGATGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKK------VIGMTETAKFR
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHT--SVSEFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCTLSVSEILYT--AA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVGCSWAGGSVM----GMVVTSAIFHLTFCGPNEIHH-FFCHLPP
-LLKLACGDDVLVVAKGVRLVCTMALLGCFLLILLSYAFIVAAILKIPSAEGRNKT----
-----F--------------FTCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---NVA---MKK-----------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MM-RRNHT--EVSEFVFQGFSSFQ-EYKFT----LFMIFLT-LY
LLTLTGNVI-IVIIISIDRHLHT--PMYFFLCMLSTSETVYT--LV--------------
I-VPR---MLSSLVGSSQ-SMSLASCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNKKVCAQLVLGSCGIGLLV----AIIQIASVFRAPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIINFIISSLVIVVPMGLVFVSYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKKALV---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-PTNGT--SWRGFVFLGFSSFG-ELQLL----LFALFLS-LY
VITLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLAMGNQ-TISYVGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICF
PLHYASRMNPALCGQLIGTSFLSGYFF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLVSFFFITISYAYILAAILRIPSAEGRKKA----
-----F--------------STCASHFTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QAA---LR-------NAFQGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
YCIYSIHSIQIYYAAPVP-GQNYS--MVTEFILVGFSNFPRHLLPA----FFLLYLL-RY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCTLSTSEILFT--VA--------------
V-TPR---MLVDMLSTHH-TITWTACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSNRGCARLVSWFWVGGSVM----GIMLTLIVFHLTFCGSNVIHH-FACHVLS
-LLKLTCGKETSSVTLGVILVCVSALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASIIYLKPKGLH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFWKKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--CVTEFFLLGFSSLG-DLQLV----LFVIFLC-LY
LIILSGNIT-IISVIRLDHSLHT--PMYFFLSVLSTSETFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFVSCASQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCGQLAAICVVSGFLI----SLLGTIMVFSLPFCGSNKVNH-YFCDISP
-VIHLASAE-TYINQLVIFIGGVFVLVVPLTCICISYGFIVSTILKIPSTEGKQKA----
-----F--------------STCASHLIV-VIVHYGCASFVYLRPSAKY-T--TGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IWK------MIGKTGFSVKT
L------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--CVTEFFLLGFSSLG-DLQLV----LFVIFLC-LY
LIILSGNIT-IISVIRLDHSLHT--PMYFFLCVLSTSETFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFVSCASQMYF-FLGFAV-TNSLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCRQLAATCIVTGFLI----SLLGTSLVFSLPFCGSNRVNH-YFCDISP
-VIRLACAE-TYINELVIFIGGVLVLVVPLICICISYGFIASAILKISSAEGKRKA----
-----F--------------STCASHLIV-VIVHYGCASFVYLRPSAKY-T--SGKDR--
-LVTVTYTVI-TPLL----NPMVYSLRNKDV---QLA---IRK------MLGKTGFSVKT
S------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TMNTFLLWGFSSFP-DLQQL----LFVVVFF-SH
VTILAANVS-IMVAIKRSHNLHT--PMYFFLYGLSLSETCTS--MV--------------
I-IPR---MLVDLQSETK-MISLPECATQMFF-FFGLGT-NNCFILAAMSYDRYS-AIHH
PLHYSILMTPKICFQMMMASFVVGILV----SLCVVSIVFTLSFCDSKTIRH-FFCDITP
-VVSLACDY-TFLQKMILLAFSPFVLVGSFILIMISYVLILSIVVKMTSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFACFSYLRPKNN---DSFNEDT--
-LMALTYTVL-TPLL----NPIVYSLRNKAM---QIA---LRK------VVGNAKSFIT-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSKVILTENVT--MVTEFLLLGFSSLG-EIHLA----LFVVFLF-LY
LAILSGNVT-IISIIRLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGLMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPVVYSLRNKDV---QLA---IRK------VLGKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVVLAENIT--MVTEFLLLGFSSLG-EIQLA----LFAVFLF-LY
LAILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIHLACTN-TDVNEFLIFICGVLVLVVPFLFICVSHLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASFIYLRPTANY-V--SSKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLQ
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENHT--FILEFVFQGFSRFC-EHQLT----LFLVFLT-LY
ILTLAGNII-IVTIIQIDPHLHT--PMYFFLGMLSTSETVYT--LV--------------
I-LPR---MLSSLVGMSQ-SISLAGCATLMFF-FVTFGI-TNCFLLTAMGYNRYV-ATCN
PLRYTVSMNKRMCAQLVWGACSIGMIV----AMTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTINEILTFIISILVLVVPMGLVFISYVLIISTILKIASVEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCVSIAYLKPKSEN---TRDQDH--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------AIGRKFF----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------LRKT
NI-FLHLNILYVIPWKQLPVENLT--MITEFLLLGFSDLQ-EMQFV----LFAVILC-LY
LLILSGNIT-IITTVYLEHSLHT--PMYFFLGVLSFSETFYT--FT--------------
I-LPK---MLLNLLSVLR-TISFISCATQMFF-FLGFAI-TNCLLLGVMGYDRFT-AICH
PLRYPVLMSWWICKLMAATCGVAGFVI----SMVGTFFGFTLPFCNSNRVNH-YFCDIAP
-VIHLACGD-PYINEVIIFIGGVVILMVPLTFICITYGFIVRTILKIPSTEGKKKA----
-----F--------------STCASHLTV-VVVHYGCASFVYLRPSSKY-T--SSKDR--
-LVTVTYTII-TPLL----NPLVYSLRNKDV---QMA---IRK--------EWNSYSSLT
FYD----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------ILL
IF-ISMYHNAFFFPPFQVLAENLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IVSVICLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
L-LPK---MLTNLLSVAR-TISFTCCATQMFF-FLGFAI-TNWLLLGVMGYDRYA-AICR
PLHYPILMSWQVCGKLGATCGIGGFLA----SLKVVYLVFSLPFCSANKINH-LXXXXXX
-XXXXXXX-----XXXXXXVEFILVLVVPFLFICVSYICILRTILKTPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASYIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QVA---IRK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-LWNET--TWRDFVFLGFSSFG-NLQFL----LFAIFLF-LY
LITLTSNVF-IIVIIQLDSHLHT--PMYLFLSVLSFSETCYT--LG--------------
I-IPK---MLLNLAVGSQ-AISYMGCAIQMDF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMHPTLCTQLVGTSFLSGYLV----GMGMTLVIFQLPFCGSHEIHH-FFCDTPP
-VLSLACGD-TSMSELGILILSLLVLLVSFSLITISYVNILVTILRIPSAKGKQKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNQAV---QAA---FK-------NALQGKLLGKR
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NSS--RVTEFLLLGFSSFG-ELQPV----LFVLFLS-LY
LIILSGNFT-IISVIRLDRSLHT--PMYFFLCVLSTSEVFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFTSCATQMFF-FLGFGI-TNCLLLGVMGYDRCT-AICQ
PLRYPVLMSWRVCAQLAATCIVSGFLV----SLVGTTLVFSLPFCGSNRVNH-YFCDISP
-VIRLACAE-TYINELVIFVCGVLVLVVPLIFICISYGFIVRTILKIPSADGKRKA----
-----F--------------STCASHLIV-VIVHYGCASSVYLRPSAKS-S--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------VIGKTAVSLKT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MMINQT--ILKEFILVGFSVYP-HVQTA----LFVIFFC-LY
MFTLAGNLV-IMGLTWVDRSLHA--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLDKDS-HISVTGCGLQMCF-FLGIGG-TNCILLTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVPFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFIVTLMSASGLLGTFLLILLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASVVYLKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDM---KNA---FKK------IMRKTVIMKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------CGKMATACGVGGFLV----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVHEFVIFICGVLVLVVPFFCICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IKK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-ESNVT--CWRGFVFLGFSSFR-ELQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTVCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGSLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLCFRFGNQSMK-RENFT--LITDFVFQGFSSFR-EQQIT----LFGMFLA-LY
ILILAGNII-IVTIIRIDHHLHT--PMYFFLSMLSTSETVYT--LI--------------
F-LPR---MLSSLVGMSQ-PISLAGCATQMFF-FVTFGI-TNCFLLTAVGYDRYV-AICN
PLRYMVIMNKRLRIQLVLGACNIGLIV----AITQVTSVFRLPFCARK-VSH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVEGWKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDHDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEVIFLGFSSFG-NHQIT----LFVVFLT-VY
ILTLVANII-IVTIICIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPQ---MLSSLIFHDQ-PISLAGCATQMFF-FVIFAT-NNCFLLTAMGYDRYV-AICR
PLRYTVIMSKGLCAQLVCGSFGIGLTM----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVKKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--SWRDFVFLGFSSSG-ELQLL----LFALFLS-LY
LVTLTSNVF-IIIAIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLAGGDQ-AISYVGCAAQMFF-SASGAC-TNCFLLAAMGFDRYV-AICA
PLHYASRMNPTLCAQMVITSFLTGYLF----GLGMTLVIFHLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TGPSELRIFILSLLVLLVSFFFITISYAYILAAILRIPSAEGQKKA----
-----F--------------STCASHLTV-VIIHYGCASFVYLRPKAS---YSLERDR--
-LIAMTYTVV-TPLL----NPIVYSLRNRAI---QTA---LR-------NAFRGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LC-GQNYS--TVSEFILIGFSSFPQHLLPA----FFLLYLL-MY
LFTLLGNLL-IMATIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADMLSTHR-SISFMACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNMLMRTRDCAHLVSWSWAGGSVM----GMMLTLIVFHLTFCGSNEIHH-FVCHVLS
-LLKLACGKEILSVTMGVILVNSTTL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--SWRDFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTLTSNVF-IIIAIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLAMGDQ-AISYVGCAAQMFF-SASWAC-TNCFLLAAMGFDRYV-AICA
PLHYASRMNPTLCAQLVVTSFLIGYLF----GLGMTLVIFHLSFCSSHEIQH-FFCDMPP
-VLSLACGD-TGPSELRIIILSLLVLLVSFFFITISYAYILAVILRIPSAEGQKKA----
-----F--------------STCASHLTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAMTYIVV-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLCFRFGNQSMK-TENFT--LITDFVFQGFSSFH-EQQIT----LFGVFLA-LY
ILTLAGNTI-IVTIIRIDHHLNT--PINFFLSMLSTSETVYT--LV--------------
I-LPR---ILSSLVGMNQ-PISLAG----------------------SMGYDCYV-AICN
PLRYMIIMNKRVHIQLVLGACSIGLIV----AITQVTSVCRLPFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVE----G-R-K
-K-A-F-A-------------TCASHLTV-VTIHY-------------------------
----VTYTVI-TPLL----NPVVYTLRNKEV---KDA---LSR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--GVTEFVFLGFSIFG-KHQIT----LFVVFLT-IY
ILTLAGNII-IVAIICIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHNQ-PISLAGCATQMFF-FAILAA-NNCFLLTVMGYDRYV-AICK
PLRYTVIMSKRMSAQLVCGSFGTGLVM----AVLHVTAMFNLPFCGTV-VNH-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVILVPAGLISISYILIISSILKITSAKGRKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SIEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---IHR------AMGKSIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------SLLC--WM-KENHS--LVNVFTFQGFSSFR-EHKLT----LFVVFLT-LY
IFTLAGNVI-IVSIISIDRHLHT--PMYFFVSMLSGSETVYT--LV--------------
I-IPR---MLFNLIGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVVMSKRVCMQLVWGACSIGLIV----AMTQVSAVFRLPFCIPK-VPH-FFCDIRP
-VMKLSCID-TTVNEILTMIISVLVILIPMGLVFISYILIISTILKIASAESRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------VIGQKFS----
-------------------------------

----------------------MEWVNETLVREFVFLSFSSLAGLQ--RVLFVVFLLLYL
FTLGTNAVI-ISTIVLDRALHTPMYFFLAILSCTEICYTFVIVPKMLIDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGRGMCVGLVAAAYACGFTV
AQIITPLVFRLPFHSSNQLHHFFCDISPVLQVASHHTHFNQIVIFILCPLVLVIPLLLIL
VSYVHIISSILQ-FPSTLSRNKAFSTCASHLIVVTVHYGCASFIYLKPKSNYSSSQDALI
SISYTILTPLFNPM-IYSLRNKEFKSAFHRVIGRKLSLSQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----GSLL-IMATIWSERSLHT--PMYLFLCALSISEVLYT--VA--------------
I-IPR---MVADLLSAHC-SITLPACASQMFS-SFTFGF-THSFLLTVMGYDRYV-AICQ
PLRYHVLMSPHGCACLVGWSWAGGFMV----GMVVTTAIFQLTFCGSHEIQH-FLGHVPP
-LLKLACGHHVPAVALGVGLVCITAQLGCFLLILLSYAFIVATILNIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGPH---SQEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KVA---LKK------TLLGKLHSSDT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KLNST--FVTEFLFEGFSSFRWQHKLV----FFVVFLT-LY
LLA----------------------------IMLSISETCYT--V---------------
-------------------PIATQSCATQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRYSVIMGKRACIQLASASLGIGLGM----AIVQVTSVFGLPFCDGFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCTSHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTHH-SPTE----PCCVQP---EEQ---G-G---QRC------SAQSRGAKDSV
SLMKR-------------GCEGFSFAFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-TANYT--EVRQFVFQGFSTFQ-EHQLT----LFVVFLT-LY
ILTLTGNVI-IVTIICIDYHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLSSLVGLSQ-SISLEGCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLHYSIIMNWRVCAVLASSVCATGFSL----SLLQAVAIFRLPFCKTL-IEH-FFCDVRP
-LLDLACAT-PIINDILTLIISLLAITAPATFLFISYVLISSTILKIASAEGRKKT----
-----F--------------ATCISHLTV-VIVHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRR------VVGRKSFS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-IVLNAHCFFFQISETQTMWINQT--ILKEFILVGFSLYP-DIQAF----IFIVFLC-LY
LFTLIGNTA-IMGLTWVDRALHT--PMYLFLSALSFSETCYT--MS--------------
I-IPK---MLADLLAKNR-SISVVGCGLQMCF-FLGLGG-TNCLILTVMGYDRFL-AICN
PLRYPLLMTNAVCGQLVASAWVGGFFV----SLVETSLIFRGFFCNRNVVKH-FFCHMRV
-IVKLSCLD-SDFTEFIVTVISVSGLLGTFLLISLTYIFIFSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAIPYTVI-TPFL----SPLIFTLRNKDM---KNA---FRK------VLGKTVALDK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANFS--AVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWRERSLHT--PMYLFLCALSTSEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLVVTSAIFHLIFCGPNEVHH-FACHVPP
-LLKLACGTDVQVVAKGVGLVCIAALLGCGLLILLSYAFIVATILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-QDNAT--CWRDFVFLGFSSFG-KLQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTLCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSIACGD-TRLSELGILILSLLVLLISFFLISVSYAYILVAILSIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QSA---LR-------NAFRGTLLGKG
-------------------------------

----------------------MEWANETLVTEFVFLGFSSLAGLQ--RLLFAVFLLVYL
FMLGTNVVI-VSTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLGDLLAQKKTISFL
GCAIQMFFFLFLICSHSFLLAAMGYDRYVAICDPLRYTVLMGFGVCMGLVAAACACGFII
SLATTSMIFHLPFHSSNKLHHFFCDVSPVLKLASHQSYFNQLVIFVLGVFVLVIPLLLIL
VSYVLIISAILE-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPV-IYSLRNKEFKSGLQRAMTHTSYSIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------M-MRKKPHSAMGYDRYV-AICN
PLRYSVIMNKRPTIXXXXXXXXXX-------------XXXXXXXXXXX-XXH-YFCDIRP
-VMKLSCAD-TTLHDIVNFIISSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKKTLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KSNTT--SVTEFLFEGFSSFAWQHRLA----LFAIFLT-LY
FLTLSGNVI-IVSIIHLDHHLHT--PMYFFLAVLSISDTCYT--VT--------------
I-IPR---MLSDLLNPYH-TIAFRDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGKRACFHLASGSLGIGLGM----AIVQVTSVFSLPFCDGFVIPH-FFCDVRP
-LLKLACTD-TTINEIINFVVSVCVLILPMGVVFVSYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYMKPKSQS---LLGQER--
-LISVTYTLI-TPLL----NPLVYSLRNKEV---KDA---LRR------ALWQKPLLS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFVFLGFSSFG-KHQIT----LF--------
--MLAGNII-IATIIRIDHHLHT--PMYFFLSMLASSVTVYT--LV--------------
I-VPQ---MLSSLIFHNQ-TISLAGCTTQMFF-FVILVI-NNCFLLNVMSYGRYV-AISK
PLRYMTIMSRGLCTQLVCGSFGTGLVM----AVLHVTAMLSVPFCDTI-ADH-FFCAIYP
-VV------------------SSFVIFVPICLIFISYTLIISSILKIAFAGGRKKT----
-----F--------------GTCASHLTV-VIVHYGCAPIAYLKPKSES---SVEKDLLN
LLISVTYTII-TPLL----NPVVYSLRNKDV---KDA---LSR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MQTNQT--IVKEFTLLGFSLYP-DAQIS----LFAVFFC-LY
LLTLMGNLT-IMSLTWVDRALHT--PMYIFLSALSFSETCYT--LS--------------
I-IPK---MLADLLAKNR-SISVIGCGLQMYF-FLGLAG-TNCIILTLMGYDRFL-AICK
PLRYPLLMTNIVCGQLVASAWAGGFFI----SLIETALIFRDFFCSSNLVKH-FFCHMRA
-IVRLSCLD-SNLTEFMVTLISESGLLGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFSFASVVFLKPEGS-----RGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VVGNIVS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSQAILTENLT--TVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNIT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMGWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYICILRTILKIPSAEGRRKA----
-----F--------------STCAAHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------PLPITAPMQ-GSNSS--SVSEFILLGFSAFPHQLLPA----LYLLFLM-MY
LFTLLGNLL-IMATVWHQRSLHV--PMYLFLCALSISEILYT--FA--------------
I-IQR---MLTDLLSTQH-SITLLACASQMFF-TFTFGF-THSFLLTIMGYDRYL-AICH
PLRYSVLMSPRGCGCLVAWSWVGGLVM----GLVVTTAIFHLTFCGPNEVHH-FFCHIPP
-LLELACGGNVPAVAMGVGLVCITDLLGCFVLILLSYAYIVATILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASIIYLKPKGPA---SPEGDT--
-LMATTYTIL-TPFL----SPIIFSLRNKEL---KMA---MKR------TFLSELCGDKS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VP-GQNYS--MVTEFILVGFSNFPRHLLPA----FFLLYLL-MY
LFTLLGNLL-IMTTVWSERSLHT--PMYLFLCALSTSEILFT--VA--------------
I-TPR---MLVDMLSTHR-TITWAACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSPRGCARLVSWSWAGGSIM----GMMVTLIVFHLTFCGSNVIHH-FACHVLS
-LLKLACGKETSSVTLGVILVCVSALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYIVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------S--SMSGFILIGFSTFLPKLLTA----FF---LL-MY
LFTLLGNLL-ILAIVRSERSLHI--PTYLFL-----------------------------
----------------------------QMFF-SFMFDF-THSFLLIAMWPSAT------
-----------PSPGAVPAWWAGPALVALSGGAGGDTAIFQLTFCEPYEVQH-FLCHVPP
-LLKLACGSNVPAVALGVGLVCIMALLGCFLLILLSY-----------------------
--------------------STCASHLIV-VFMHYGFASVIYLKPKGPH---SQESDT--
-LMATTYTVL-TLFL----SPIIFSFRNKEL---NVA---RKK------TFFSKLYSLGT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--SVSEFILIGFSTFPQHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWSEGSLHT--PMYLFLCALSTSEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLLVTSAVFHLPFCGLNEVHH-FFCHVPP
-LMKLACGNNVPGVALGVGLVCSMVLLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYSFASVIYVKLTGLH---SQQGNI--
-LIAITYTIL-TPFL----SPIIFSLRNKEL---KNA---MKK------TFLSKLYLSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------VCLQAAERLWGNGSR--LVTEFVLVGFSHLP-HLRTT----LFTLFLL-TY
LVTLSGNAT-IITVIQADRTLHT--PMYRFLALLSLSETCYT--LV--------------
T-IPN---MLAHLLTERH-AISVPACRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICR
PLRYSVVMRPTVCLCLGAVVFCSGFSV----ALIETCMIFSSPFCRGSRVEH-FFCDIAP
-VLRLSCTQ-SPGRALGIFFLSVLVVLASFLLILLSYAFIVATILRMPSATSRHKA----
-----F--------------STCAAHLTV-VLVHFGCAGVIYLRPDSGA-H--PERDR--
-LVAVFYTVV-TPLL----NPVVYTLRNREV---RVA---LRR------TLARGCGAEQR
GPA-DRHS-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RMNFT--EVTEFIFLGFSSFG-KHQIT----LFVVFLT-IY
ILTLAGNFI-IVTITYMDRHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFYDL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICE
PLRYTVIMSKGLCAWLVCGSLGTGLVM----AVLHVPAMFHLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTVNEIINYGVSSFVILVPIGLIFISYVLIVSSILKIVSTEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYIII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQGFNKTT--VVTQFILVGFSSLG-ELQLL----LFVIFLL-LN
LTILVANVT-IMAVIHFSWTLHT--PMYDFLLILSFSESCYT--FV--------------
I-IPQ---LLVHLLLDTK-TITFMACANQLFF-FLAFAW-TNCFLIAVMGYDRYV-AIS-
----------------------TGFFF----ALVATNHICDMAFCGPNRVNH-YFCDMAP
-VIKLACND-THVKELALFSLSIQIIMVPFLLILISYGFTVNTILKIPSAEGKKKA----
-----F--------------ATCPSHLTM-VFVHYGCASIISLWPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----SPLVYSLRNKEV---KTA---LKR------VLGMPVATKMS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LHP
VA-DLSLSHFTPGTAFMQ-RGNFS--VVTEFILVGFSSFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATVRSERGLHM--PMYLFLCALSISEILYT--LA--------------
I-TPH---LLADLLSTRH-AITFVACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWSWVGGSVM----GLVVTMAIFHLTFCGPNEVHH-FACHVPP
-LLKLACGTDVPIVALGVGLVCISTLLGCFLLILLSYAFIVTTILKIPSAEGQHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKASQ---SLEGDT--
-LMGITYTIL-TPFL----SPIIFSLRNKEL---KNA---IKK------TFFSTLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EITEFIFLGFSGFH-EHQIT----LFVVFLI-LY
TLTLAGNAI-IVTIIHTDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-IPR---MLSSLIAQNQPPISLACCATQMFI-FLTLAI-NNCFLLMVMGYDRYV-AICN
PLRYTNIMSKWVCVRLVCGAFSIGLAM----AAVQVTSIFTLPFCHRV-VGH-FFCDTLP
-VMKLSCID-TTINEIINFVVSLSVILVTMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---SLEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------TVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHT--PVSEFILIGFSAFPPHLLPI----FFLLFLL-MY
LFTLLGNLL-IMATVWSERGLHT--PMYLFLCALSISEVLYT--VA--------------
F-IPR---MLVDLLSAQR-RISFQACATQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYPVLMGARGSVHLVAWSWVGGIII----GLVVTATIFNLTFCGPNQIQH-FLCHVPP
-LLKLACGHNVPVMALELGTVCITALLGCFVLISLSYAFIIAAILKIPSAEGKHKA----
-----F--------------STCASHLMV-VVVHYGFASVIYLKPKDTD---SQKSSA--
-LMSVTYTVL-TPFL----SPIIFSLRNKEL---KAA---MKK------AFLSRLYPSHT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------MTRKVCFQLMMASAVVGFLV----SLCIVIIVFNLSFCDSNTIQH-FFCDIAP
-IASLACSY-TFFQKMVLLAFTAFVLVGSFILIMISYVFIVSLVVKMPSAKGRRKA----
-----F--------------STCSSHFTV-VSVHYGFACFVYLRPKNSD-SDSFSEDT--
-LMAVTYTVL-TPLL----NPIVHSLQNKEM---QVA---LRR------VLGSIMKFAPQ
MANK---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVAEFIFLGFSIFG-NHQIT----LFVVFLT-TY
IFTLTGNII-VITVICIDRHLHT--PMYFFLSMLSSSETVYT--LV--------------
I-IPR---MLSGLIFYNQ-PISLGSCATQMFF-FAMLAI-NNCFLFTVMGYDRYV-AICK
PLRYTVLMNKGVCARLVCGSFGTGLVM----AVLHVMAMFTLPFCGTM-VDH-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVIIVPVVLVFISYILIISSILKISSVEGRKKT----
-----F--------------ATCASHLTV-VVVHYGCAAIAYLKPKSEN---AIEKDL--
-LLSVTYTII-TPLL----SPVVYSLRNKEV---KDA---LCR------AVGRISS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNSS--FVTEFLFEGFSSFRWQYRLV----FFVVFLT-LY
LLTLSGNVI-IMTIVRLDHHLHTPRPMYFFLSMLSISETCYT--VV--------------
I-IPY---MLSGLLNPHQ-PIATHSCATQLFF-CLTFGI-NNCFLLTVMGYDHYV-AICN
PLRCSVIMSKRACIQLASVSLG--I----------VTSVFG----------------LPP
-LLNLACTD-TTVNEIINFVVSVCVLVLPMDLVFVSYVLIISTILMIASAEGRKKA----
-----F--------------ATWASHLTV-VIIHYGCASIIYLKRKSQS---SLGQDR--
-LIAVI----------------YTP---EEQ---GDA---LRY------SVQSHGAKAPV
SFTKR-------------GCEAFFFEFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------ILQFRSWNS-MK-TDNQT--LIAQFTFQGFSSFQ-EHQLT----LFVVFLA-LY
LLTLVGNVI-IVTIISLDRRLHT--PMYFFLSVLSASETVYT--LV--------------
I-IPR---MLSSLVGLGQ-PISLGACATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSLIMNKSICAQLVGGALSIGLLV----AIIQISSVFRLPFCGTE-VAH-YFCDIRP
-VMKLSCAK-NDMHDIMTFVISSLVILVPMGLVFISYVLIISSILRIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---SRDEDQ--
-LISVTYTVI-TPLL----NPMVYTLRNKEV---QHA---LRR------VMGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--VITEFILIGFSNLG-DLQIL----LFFIFLI-VY
LSTLMANAT-IMTVIRLDRTLHT--AMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLSNLLATVP-SISFAGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRATCGHLVLASSLCGFLI----SVVVNLLVFSVPFCASNRIDH-FFCDIFP
-VLKLGCTD-TNLKEMAIFLLSILVLLVPFVLIFVSYVFIVSTILRISSVEGQRKA----
-----F--------------ATCASHLTV-VVIHYGCASFIYLRPTSLY-S--SDKDS--
-LVAVTYTVI-TPLL----NPVVYTLRNKEV---KTA---LRK------VLSRYSFPKAV
-------------------------------

------------------IAVTMEWANETLVTEFVFLGFSSLAGLQ--QLLFAVFLLVYL
FMLGTNIVI-VSTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFFFLFLICSHSFLLAAMGYDRYVAICNPLRYTVLMGFGVCMGLVAAACACGFII
SLATTSMIFHLPFHSSNKLHHFFCDVSPVLKLASHQSYLNQLVIFVLGVFVLVIPLLLIL
VSYVLIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSSLQRAMTHTSYSIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TQ-DANFS--AVTEFILIGFSSFPHLQ-LM----FFLLFLL-VY
LFTLLGNLL-IMATVWSECSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTDL-SISFVACASQM-F-SFTPGF-THSFLLTVMGYDRYL-AICH
PLRYNVLMNPRGCACLVVWSWTGGLVV----GLVVTSSIFQLTFCGSNEIRY-FGCHVLP
-LFKLACGDNVSTVAKGVGLVCIAALLGCCLLILHSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KEA---MKK------TFLSKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------IL-RLNYT--SVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATIWKEDSLHT--PMYLFLCALSISEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFTACASQMFF-SFTPGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGLVV----GLVVTSSIFQLTFCGSNEIHY-FGCHVPP
-LLKLACGTEVQVVAKGVGLVCIAALLGCGLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KEA---MKK------TFLSKLYTSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GGNFS--SAAEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWREHSLHT--PMYLFLCALSISEILYT--FA--------------
V-IPR---MLADLLSTDH-SIALRACASQMFF-SFTFGF-THSFLLTIMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVI----GLVVTVAIFQLTFCGSNEIHH-FVCHVQA
-LLKLACGENVSILAMGLGLVCIAALLGCCLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCVSHLTV-VIEHYGFASVIYLKPKGPQ---SLEIDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HS--TVTTFLLWGFSSFP-ELHNL----LFVVILL-SH
VTILLANAS-IMVAIKLNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSESK-AISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLHYHIFMTPKVCFQLVIASCVVGFLC----SLSITFTIFNLSFCDSKIIQH-FFCDISP
-LVHLACDY-TAHHAMIIFMVSAFVLVGSFVLIMISYAFIVFLVVKMPSAQGRHKA----
-----F--------------STCSSHLTV-VSMHYGFACFVYLIPKNS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VVSSINKMLPC
LAIKKPEHLRTT-IEH---------------

----------------------MERVNETVVREFVFLGFSSLARLL--QLLFVIFLLLYL
FTLGTNAIF-ISTIVLDRALHTPMYFFLAIVSCSETCYTFAIVPKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCCHSFLLAAMGYDRYRAICNPLHYSVLMGHGMCMGLVAAACACGFTV
YLVTTFLVFHLPFHSSNHLHHFFCDISPVLKLASQHSDLSQLVIFMLGVFALVIPLLLIL
VSYIRIISAILKKISSSVGRYKTFSTCASHLIVVTVHYGCYSFIYLRPKTNYSSREDTLI
SVSYNILTPLFNPM-IYSLRNKEFKSAL--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENHT--AVGEFVLQGFSSFR-EHKII----LFVIFLT-LY
LLTLAGNVI-IVTVISFARHLHT--PMYFFLGVLSTSETVYT--LV--------------
I-VPR---MLCSLTGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRACALLVSGACSIGLFV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIINFIISSLVIVVPMGLVFISYILIVSTILKIPSARGRKKA----
-----F--------------ATCASHLTV-VVFHYGCASVAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LHR------AIRKNPLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TL-GLNHS--SVSEFILVGFSTFPPHLLPA----FFLLFLL-MY
LFTLLGNLL-IMATVWSERALHT--PMYLFLCTLSISEILYT--LA--------------
I-TPR---LLADLLSTRR-TIAFAACTSQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWSWAGGSVM----GLVVTTAVFHLTFCGPNEIHH-FFCHVPP
-LLKLACGTDVPIVALGVGLVCITALLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKAPQ---SLEGDT--
-LMGITYTIL-TPFL----SPIIFSLRNKEL---KTA---MKK------TFLSKLYPQSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MINQT--ILQEFILIGFSAYP-LVQTC----LFVVFLC-LY
MVALASNLT-IMGLTWADRYLHT--PMYYFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLDKDN-RISDIGCGLQMCF-FLGLGG-TNCILLTVMGYDRFL-AICN
ALKYPLLMTNVACGQHVATAWVGGFLI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFIVTLMSVSGLLGTFLLILLTYVFILSSVLKTPSAEGKQKA----
-----F--------------TPCASHLTV-AIIHFVFAPVVYLKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDI---KNA---FRK------IMRKTVVLKK-
-------------------------------

----------------------MERVNETVVRDFIFLSFSSVARLQ--QLLFVIFLLLYL
FTLGINGII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVIVPKMLVDLLAQRKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYVAICNPLRYSVLMGHGMCMGLVAAAYACGFTV
AQIITSLVFHLPFYSSNQLHDFFCDISPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHIISAILQ-FPSTLGRYKAYSTCVSHLIIVTVHYGCASFIYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCRIARRTISLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNST--FVTEFLFEGFSSFRWQYRLV----FFVVFLT-LY
LLTLSGNVI-IMTIVRLDHHLHTPHPMYFFLSMLSIFETCYT--VA--------------
I-IPY---MLPGLMNPHQ-PIATHSCAIQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRCSVIMSKRACIQLASVSLGIGL----------LTSVFGLLFCDTFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMDLVFVSYVLIISTILTIASAEGWKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPNDLHCHHSPTEHC--
-----C----------------VQP---EEQ---GDA---LRC------SAQSHGAKAPV
SFTKR-------------GCEAFFFEFINMY

----------------------MERVNQTVVREFIFLGFSTLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYVAICNPLRYSVLMGHGMCMGLVAAACACGFTV
AQIITSLVFHLPFYSSNQLHHFFCDISPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHILSVILQ-FPSTLGRCKAFSTCVSHLIIVTVHYGCASFIYLRPQSNYSSSXXXXX
XXXXXXXXXLFNPM-IYSLRNKEFKSALYKIVRRTISLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MEQVNETLVREFVFLSFSSLAGLQ--WLLFIVFLLLYL
FTLGTNAII-ISTIVLVRALHTPMYFFLAILSCSETCYTFVIVPKMLADLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHGMCVGLVAAACACGFIV
AQIITSLVFYLPFYSSNQLQHFFCDISPVLKVASHHTHFSQIVIFILCALVLVIPLLLIL
VSYIHIISAIHQ-FPSTLGRHKAFSTCASHLIVVTVHYGCASFIYLRPKSNFSSSQDALI
SISYTILTPLFNPM-IYSLRNKEFKSALRRVVGRTISLPQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRMGN-HT--TASTFFLWGFSSFP-DLQVL----LFVMIFF-TH
VAILTANLF-IMAAIKLSHSLHT--PMYFFLCGLSFSETCNT--LV--------------
I-IPR---MLVDLLSESK-TISLLECATQMFF-FFGLAG-NNCFIMTSMAYDRYT-AIHN
PLHYSMLITRKVCFQLMMASWVLGFLV----SLCIVLIVFSLSFCDSTTIQH-FFCDIAP
-VISLACDS-TSLHEVLIFVLSAFVLVGSFILIMISYVFIVFLVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFAFVVYLRPKKN---DSFYEDM--
-LMAMTYTVL-TPLL----NPIVYTLRNKEM---QLA---LRK------VLGNANR----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------FVTEFLFEGFSSFRWQYRLV----FFVVFLT-LY
LLTLSGNVI-IMTIVRLDHHLHTPHPMYFFLSMLSIFETCYT--VA--------------
I-VPY---MLSGLLNPHQ-PVATHSCATQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRCSVIMSKRACIQLASVSLG--I----------VTSVFGLLFCDAFVISH-FFGDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMDLVFVSYVLIISTILTIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPNDLHCHHSPTEHC--
-----C----------------VQP---EEQ---GDA---LRC------SVQSHGAKAPV
SFTKR-------------GCEAFFFEFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GHNLT--EVTQFVFLGFSRFR-EHQTI----LFVVFLI-LY
TFTLAGNAI-IVTVVCTDRHLHT--PMYVFLSVLAGSETAYT--LV--------------
T-IPR---MLSGLLAQNQ-PISSAGCATQMFF--IALAI-NNCFLLTAMGYDRYV-AICD
PLRYTVVMSKRVCVQLMCGVSGIGLAM----AVVQVTSIFTLPFCHRV-IGH-FFCDILP
-VLKLSCID-TTVNEIINFVVSSFVILVPVGLVFVSYVLIISTILRIRSAQGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SIEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGRNI-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANHS--TVTQFILIGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEILYT--VA--------------
I-IPR---MLADLLSTQH-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPWGCTCLVGCSWAGGLVM----GMVVTMAIFHLTFCGRNEIHH-FACHVPP
-LLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFFSKLYPEKN
V---M-M------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LYLWRRVATYTKRMGN-HT--TVSTFLLWGFSSFS-DLQDL----LFVMVFF-SH
VTILAANTS-VMLAVKLSHNLHT--PMYFFLCGLSFSETCTT--VV--------------
V-IPR---MLVDLLSDSK-SISIPECATQMFF-FFGLGT-NNCFILAAMSYDRYT-AIHN
PLHYSILMTRKICFQLMMASCITGVVV----SLCIILIVFNLSFCDSSIIQH-FFCDITP
-VVSLACDY-TIFQKMILLAFTAFVLVGSFILIMISYVFIGSIVMKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCTHYGFAGFVYLRPKSR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LKK------ALGNICRFS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MITVLGSEIVLAENIT--MVTEFLLLGFSSLG-EIQLA----LFAVFLF-LY
LAILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGVTGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTAVNLVFSLPFCSANKVNH-YFCDIPP
-VIHLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASFIYLRPTASY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLQ
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MT-GDNQS--MIIEFILVGFSNLG-DLQIL----LFFIFLL-VY
LTTLMANTT-IMTVIRLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSSNP-TISYYGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYMLI--------LVLVSGFCGFLI----SVVVNILVFSVPFCASDRINH-FFCDISP
-VIKLGCTD-TSLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSLEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDL--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KVA---LRK------VLNRYSLPK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TK-SENHT--LTTEFVLQGFSSFH-EHQLT----LFVMFLA-PY
ILTLAGNII-IVIIIRIDHHLHT--PMYFFLSMLSTSETIYT--LV--------------
I-LPR---MLSSLVGMSQ-SISLAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICH
PLRYTVIMNRRVCIQLVWGACSIGLIV----AMTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVFVLVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SKDEDQ--
-LISVTYTVV-TPLL----NPVVYTLRNKEA---KDA---LLR------AIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MH-RKNFT--EVTEFIFLGFSSSG-KHQIT----LFVVFLI-IY
ILTLASNII-IVTVICTDHHLHT--PMYFYLSMLASSETVYT--LA--------------
I-VPR---MLSSLIFHKQ-PISLAGCATQMFF-FVIMAT-NNCFLLTAMGYDRYV-AICK
PLRYTVIMSKGMCAQLVCGSFGTGLVM----ALLHVTAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCID-TTVNEIINYSVSSFVIFIPVCLNFISYVLIISSILKIASAEGRKKV----
-----F--------------TTCASHLTV-VIVHYGCASIAYLKPKSEN---SVEKDL--
-LLSVTYIII-TPLL----NPVIYTLRNKEV---TDA---LRR------AVGKNVP----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-WLNHS--SMSGFTLIGFSTFPQKVLPA----FFLLFLL-MY
LFTLLGNLL-IMATVWSERVLHT--PMYLFLCTLSISEILYT--MA--------------
I-IPR---MLADLLSTQR-SITLLACASQMFS-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPQGCACLVGWSWAGGLVM----GMVVTMAIFQLTFCGLNEIHH-FFCHVPP
-LLKLACGDDVPVVSLGVGLVCIMALLGCCLLILLSYAFILVAILKMPSAEGRHKA----
-----F--------------STCASHLSV-VVVHYGFASVIYLKPKGPQ---SLQGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKDL---KSA---MKK------TFS-KLFPQNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHT--STSEFILLGFSTFPQQLLPV----FFLLFLL-MY
LFTLLGNLL-IMATIRSERSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSAHR-SISLLACASQMFF-SFTFGF-THSFLLTVMGHDRYV-AICH
PLRYNVLMSPRGCACLVGWSWAGGSVM----GLVVTTAIFQLTFCGSKEIHH-FFCHVPP
-LLKLACGDEVPLVAKGVGLVCIMALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPH---SQEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KIS---MKK------TFLSKFSLQNF
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--TENDCFWLLEISDTPNMKPNQT--ALWEFILVGFSTYP-HLQSF----LFVLFFC-LY
LLTLTGNLA-ILGLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLAQSR-SISVTGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICK
PLQYPLLMTNAGCGQLVAFAWAGGFSV----SLFETALIFRGDFCSPNLIKH-FFCQMQA
-VLRLSCVD-SDLTESIVTVMSVSGLLGTFLLITLTYVFILSSVLRIPSAQGKQKA----
-----F--------------STCASHLTV-VIVHFGFASIAYLKPEGS-----GGDDN--
-LIGVPYTII-TPFL----SPLIFTLRNKDI---KQA---FTK------ILDKSSYWDK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------FLLFSWNLSMK-TENHT--GVREFIFQGFTSFH-EHKLT----LFVIFLT-LY
LLTLSGNVI-IVTIISIDRHLHT--PMYFFLTVLSTSETLYT--LV--------------
I-VPR---MLSSLAGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYMIIMNKRVCAQLVWGACSIGLFV----ATIQISSVFRLPFCYRK-VAH-YFCDIRP
-VMKLSCAN-TTIHDIINFLVSSLVIVVPMVLVFISYIPIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---MRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LCR------AIGKKTLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNST--SVAEFLFEGFSSFGWQHRLG----FFVVFLT-LY
LLTLSGNAV-ILTIIRLDHHLYT--PMYFFLSMLSISETCYT--VA--------------
I-IPC---MLSGLLSPHQ-TISLQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYM-AICN
PLRYSVIMGKEACIQLATGSLGIGLSM----AIVQVTSVFGLPFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINVFVSICVLVVPMGLVFISYVLIISTILKIASPEGRKKA----
-----F--------------ATCASHLIV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNQDV---KDA---LCR------AVGRKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-GQNHS--AFSEFILVGFSNFPPQSLPA----LFLLYLL-MY
LFTLLGNLV-IMATIWNDHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLVDLLSMQH-SITFMACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNELMSPRGCAQLVVCVWVGGTVM----GIMVTSIVFHLTFCGSNEIHH-FACHVFS
-ILKLSCGNETSSVTVGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSVEGRHKT----
-----F--------------STCVSHLTV-VVVHYGFASIIYLKPKGPQ---SMDSNS--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KMA---INK------TFCRKVCSQIY
-------------------------------

----------------------MERVNETVVREVIFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFIIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYIAICNPLRYSVLMGHGVCMGLVAAACACGFTV
AQIITSLVFHLPFYSSNQLHHFFCDIAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHILSAILQ-FPSTLGRCKAFSTCVSHLIIVTVHYGCASFIYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCKIVRRTISLL---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MECVNDTVVREFVFLGFSSLAELQ--LLLFAVFLSLYL
FTLSTNALI-VSTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLMDLLARKKSISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICHPLRYTVLMGHRVCVGLVAAACVCGFTV
AQIITSLVFRLPFRSSNQLHHFFCDISPVLQLASHHPHSTQITIFLLCALVLVIPLLLIL
VSYIHIISAILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSSYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKDFKSALHRVIGRTVTLRQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MAINQT--TLKEFILIGFSAYP-HVQTF----LFGVFFC-LY
ILTLAGNLT-IMGLTWVDRSLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPR---MLVDLLNNDR-HISVAGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWAGGFLI----SFIQIALTFRVSLCIPNLIRH-FFCNIRA
-VVRLSCID-NSLTELIVTLISMVGLVGTFLLISLTYVFILSSVFKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIAYLKPEAS-----GGDDT--
-LIAIPYTII-TPFL----SPIIFSLRNNDM---KKA---FRK------IMSKTVVLKNN
FGLLLLV------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVSTFLLWGFSSFP-DLQGP----LFAMIFF-SH
MTILAANVS-IMVAIKLSHNLHT--PMYFFLCALSFSETCTT--MA--------------
V-IPR---MLTDLLSDSK-TISLPGCAMQMFF-FFGLGG-NNCFIMAAMSYDRYT-AIHN
PLHYPILMTHKICFQFIMASWMLGFLV----SLCIVIIVFNLSFCDS-IIEH-FFCDISP
-VVCLACDY-TFRQEMAIFVLSAFVLAGSFVFIMMSYVFIVSTVVKMPSAQGRYKA----
-----F--------------STCSSHLTV-VCIHYGFSGFVYLRPKDR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QMA---LRK------VLGTTDRLIPQ
MVNKRTRNT----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTTFLLWGFSSFP-ELRDL----LFVVILL-SH
VTILLANVS-IMVAIKLNHSLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---LLVDLISKSK-AISLPECATQMFF-FFGLGG-NNCFILSAMSYDRYT-AIHN
PLHYPILMTQKICLQLILASVVLGFSI----SLCIVIIIFHLSFCNSNIIQH-FFCDIDP
-VVSLACNL-TFYHKVILFALTAFVLVGSFIFIMVSYVFIVTVVMKMPSAKGRYKT----
-----F--------------STCSSHFTV-VFIHYGFACFVYLRPKNS---YSFRDDT--
-LLAVTYTIL-TPLL----NPIIYSLRNKGM---QTA---LRK------DIGNIISFFPK
MV-NKKAQKI---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------KNLT--EVTEFIFLGFSTFH-EQQIT----LFMVFLI-LY
L-PLAGNAI-IVSIIHIDHHLHT--LRYFFLRMLASSKAIYT--LV--------------
T-IPR---TLSDLVAQNP-PISLAGCTIRIFF-FLTLTI-NNCFLLMGKGYDHYV-AICN
PLRYTLIMSKHWLGHGSCP-----------------ISIFTLPFHHRV-VGH-FFCDTLP
-VIKFSCIE-RMR-------SSVSVILVIMGLGFTSYILII-----ITSTKGQKLA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SKDEDQ--
-LISVTYTVI-TPLL----NLVVYTLRSNEA---EDA---LCR------AICRNI-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----GNLL-IMTTIWREPTLHT--PMYLFLCALSFSKLLYT--FA--------------
V-IPC---MLPNLLSNDC-NISFMACASQMFF-SFTFGF-THSFLLTIMGYDCYV-AICH
PLCYNVLTSLSGWACLVAWSGVGGSVV----GLVVTTAIFQLTFCGSNEIHY-FGCHMPP
-LLKLACGG-IPALAIGMGLVCISALLGCGLLILLSYAFIVATIPRIPSAEDQHKA----
-----F--------------STCASHLTM-VIVHSGFASVIYLKPKGPQ---SLEGDT--
-LMGITYRVL-TPFL----SPVVFSLRNKEL---KNI---MRK------TFLSKFYPSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VL-KSNST--FVTEFLFEGFSSFEWHHRLI----FFVVFLT-LY
LLTFSGNVI-IVTIIHLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLSGLLNPHQ-PIASQSCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKRTCVQLASGSLGIGLGM----AIVQVTSVFGLPFCGAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMGLVFISYVIIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQD---SLEQDR--
-LISVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AMGQKSLSP--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--AITEFILLGFSNLG-HLQIL----LFFIFLL-VY
LTTLMVNAT-IMTVIRLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-MPK---MLTNLLSTSL-TISFSACAAQLYF-FVGLAC-TNCFLIAAMGYDRYV-AICN
PLNYTLIVSRATCMQLVFASTLCGFLI----SVVVNVLVFSVPFCASNRINH-FFCDISP
-VIKLGCTD-TNQKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSVEGQHKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KMA---LRK------VLSRYSFPKTI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------RSPPSMANSS--RVTEFLLLGFSSFG-ELQPV----LFVLFLG-LY
LIILSGNFT-IISVIRLDRSLHT--PMYFFLCVLSTSEVFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFTSCATQMFF-FLGFAV-TNCLLLGVMGYDRYT-AICQ
PLRYPVLMSWRVCAQLAATCIVSGFLV----SLVATTLVFSLPFCGSNRVNH-YFCDISP
-VIRLACAE-TYINELVIFICGVLVLVVPLIFICISYGFIVRTILKIPSADGKRKA----
-----F--------------STCASHLIV-VIVHYGCASSVYLRPSAKS-S--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------VIRKTAVSLKT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------M-QLRGA--SVSEFILVGFSTFPRHLLPA----FFLLFLL-MY
LFTLLGNLL-IMTTVWSERSLHT--PMYLFLCALSTSEILYT--LA--------------
I-TPR---LLADLLSTRH-TITWAACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSVT----GLVVTTAVFHLTFCGPNEIHH-FLCHVPP
-LLKLACGTDVPAVAKGVGLVCIMALLGCCLLILLSYAFIVATILRIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVVYLKPKGPQ---YLERDT--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KTA---MTK------TFLRKLHPSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------DVGSLS-AQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTIWREHSLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSTHH-SISFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWSWAGGSVM----GMMVTMIVFHLTFCGSNEIHH-FACHVLA
-LLKLACGKETSSVTLGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VIVHYGFASIIYLKPKGPR---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFHRKFSPSS-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GSNSS--SMSEFILLGFSAFPHQLLPA----LYLLFLV-MY
LFTLLGNLL-IMATVWHQRSLHV--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLTDLLSTQH-SIALLACASQMFF-AFTFGF-THSFLLTIMGYDRYL-AICH
PLRYSVLMSPRGCGCLVAWSWVGGLVM----GLVVTTNIFHLTFCGPNEVHH-FFCHIPP
-LLELACGGNVSAVAMGVGLVCITALLGCFILILLSYAFIVATILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASIIYLKPKGPA---SPEGDT--
-LMATTYTIL-TPFL----SPIIFSLRNKEL---KMA---MKR------TFLSELCGEKS
G---V-ST-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVSTFLLWGFSSFP-DLQTL----LFVMIFF-SH
VTILAANVS-VMVAIRLSHNLHT--PMYFFLCGLSFSETCTT--MA--------------
I-IPR---MLVDLLADCK-TISLPECATQMFF-FFGLGA-NNCFIMAAMSYDRYI-AIHN
PLHYPILMTHKICFQLLMASWMAGFLV----SLCIVIIVFNLSFCDSNIIQH-FFCDISP
-VVCLACDY-TFFQKMVLFAFTAFVLVGSFVFIMMSYVFIASTVAKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DLFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLGKTDRFIPQ
MVNKRTPDRHF------------EFTLSN--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-VPYMVFSFLDPTYDLMK-TENHT--WVSEFTFQGFSSFH-EHQLS----LFVVFLA-LY
VVTLAGNVV-IVTIISVDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-IPK---MLCNLVGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCVQLVGGACGIGLIV----ATTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCVD-TSVNETLTVIISVLVILVPMGLVFISYVLIVSTVLKIPSARGRKKA----
-----F--------------ATCASHLTV-VVVHYGCASVAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------AAGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MFTCGFFQIPNIQTMKINQT--ILQEFILVGFSVYP-HVQTF----LFVVFFC-LY
LLTLTGNLA-IMGLTWVDRALHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLADLLAKSR-SISVIGCRLQMCF-FLGLGG-TNCFILTLMGYDRFL-AICN
PLRYPVLMTNMACGQLVASAWAGGFFI----SLIETALIFKGSLCNPNLVKH-FFCHMRA
-VVRLNCLD-SDLTEFIVTMISVSGLLGTFLLIILTYIFILSTVLRIPSAEGKQKA----
-----F--------------STCASHITV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNKDM---KTA---FRK------V----------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------PWDQSSMANSS--FVTEFLLMGFSSLG-ELQLV----LFVVFLS-LY
LIILSGNIT-IISVICLDHTLHT--PMYFFLCVLSVSETLYT--IV--------------
I-LPK---MHINLLSVLR-TLSFMSCATQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLRYPVLMSRRVCGQLAVITIICGFLT----SLVGTTVVFSLPFCGPNKVDH-YFCDISP
-VIRLACAN-AHVNELVIFIGGALVLLVPLLFICISYGFIVRTILKIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASSVYLRPSAKH-T--SGKDR--
-LVTVTYTII-TPLL----NSMVYSLRNKDV---QMA---IRK------MIGKAV-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TL-GLNHS--SVSEFILVGFSTFPPHVLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYFFLCALSISEIFYT--LT--------------
I-TPR---LLADLLSSHC-TIAFAACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPHSCACLVAWSWFGGSVM----GMVVTTAIFHLTFCGPNEIHH-FFCHVPP
-LVKLACGTDVPIVAQGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKAPQ---SLEGDT--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KTA---MKK------TFLRRLYPQSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------EA-GQNYS--MVSEFILLGFSNLPQHLLPV----LFLLYLL-MY
LFTLLGNLL-IMVTVWNEQSLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSSHH-SISFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNMLMSTRTCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNVIHH-FGCHVFS
-LLKLACGKETSSVTLGVILVCVTALMGCLFLIMLSYVFIVAAILRIPSGEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASMIYLKPKGSH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
LPTRSPSLSLHPGMAATL-GVNHS--SVSEFILVGFSTFPPHLLPI----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEIFYT--LA--------------
V-TPR---LLADLLSSRR-TIAFAACASQMFF-FFTCGF-THSFLLTVMGYDRYV-AICH
PLQYNVLMSPCGCACLVALSWAGGSVI----GLVVTTTIFHLTFCGPNEIQH-FVCHVPP
-LLKLACGTDIPVVALGVGLVCMIVLLGCFLFILLSYTLIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VVVHYGFASIIYLKPKNLH---SQESNT--
-LMAISYTVL-TPFL----SPIIFSLRNKEL---KIA---MRK------TFLNKLYSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TL-ALNHS--SVSEFIFVGFSTFPPHLLPI----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEIFYT--LT--------------
I-TPR---LLADLLSSRR-TIAFAACASQMFF-SFTFGF-AHSFLLTVMGYDRYV-AICH
PLRYSVLMSPHGCTCLVTWSWAGGLVQ----GMVVTTAIFHLTFCGPNKIQH-FGCHVPP
-LLKLACGTDVPIVALCVGLMCITVLLGCFLLILLSYTLIVATILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASIIYLKPKGLH---SQESKT--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KTA---MKK------TFLSKLYSSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------A-GQNYS--MVSEFILVGFSNFPQHLLPI----FFLLYLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSSHR-SITFMACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRTCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNVIHH-FLCHVFS
-LLKLACGNENSSVTLGVILVCVTALMGCLFLIMLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYSFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IRR------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TR-GLNHS--SVSEFILVGFSTFPPHLLPI----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLADLLSTHR-TIAFAACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVI----GLVVATAIFHLTFCGPNEIHH-FLCHVPP
-LLKLACGTDVPIVALGVGLVCITNLLGCFLLILLSYTLIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASIIYLKPKGLH---SQESST--
-LMAITYTVL-TPFL----SPIIFSLRNKEL---KTA---MKK------TFLSKLYPSNI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------SFP-GQNYS--APSELLLIGFSSFPPRLLPA----FFLVYLL-MY
LFTLLGNLL-ITATVWSERGLHK--PMYLFLCALSVSEVLFT--MV--------------
I-TPR---MLADLLAAHH-TISFRACAAQMFF-YFTFGY-THSFLLTAMGYDRYV-AICH
PLRYPVLMGARGCARLVAWSWAGGSVV----GTTMILIIFRLRFCGSRVIHH-FVCHVLS
-LLKLTCGQETFPATVAVILVCVSVLLGCLLSVALSYAFIVAAILKIPSTEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASVIYLKSTAPR---SVYTDT--
-LLSTTYTAL-TPFL----SPIIFSLRNKEL---KAA---IQK------CIHRKVRLLGS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSLG-KHQIT----IFGVFLT-VY
VLTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEKVYT--LV--------------
I-VPR---MLCSLIFHNQ-PISLAGCASQMFF-FVILAI-NNSFLLTAMGYDHYV-AICR
PLRYTVIMSKGLCAQLVCGSFGI---------VLQVTVMFNLPFCGTV-VDH-FFCDIWP
-VMKLSCID-TTIDEIINYDV---------SLIFTSYVLIISSILKIASAEGWKKT----
-----F--------------ATCASHLTV-VIVHCGCSSVAYLKPKSEN---STEQDL--
-LLSVSYTII-TPLL----NPVVYSLRNKEV---KNA---LRR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------FLCFRFGNQSMK-TENFT--LITDFVFQDFSSFR-EQQIT----LFGVFLA-LY
ILTLAGTTI-IVTIIRIDHHLNT--PMNFFLSMQFTSETVYT--LV--------------
I-LPR---MLSSLVGMIQ-TISLAG----------------------SMGYDCYV-AICN
PLRYTVIMNKRVRIQLVLGACSIGLIV----AITQVTSVCRLPFCARK-VPH-FFCDIRP
-EMKLFCID-TTVNEILTLIISVLVLVV-------SLVLIISTILKIASVE----G-R-K
-A-A-F-A-------------TCASHLTV-VTVHY-------------------------
----SWASI------------AYLKPKNKEV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTMFLLWGFSSFP-ELQHL----LFIVILF-SH
VTIILANAS-IMVAIKLSHNLHT--PMYFLLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSESK-AISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLQYHIIMTQKVCIQLVMATCVVGFLC----SLGITFTIFNLSFCDSNNIQH-FFCDISP
-LVHLACDY-TVHHAMIIFMLSAFVLVGSFVLIMISYVFIVSLVVKMPSAQGRYKA----
-----F--------------STCSSHLTV-VSMHYGFACFVYLIPKNS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLHSVNKILPC
LASKKALDI----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-HTNAT--CWKGFVFLGFSSFG-DLQLL----LFALFLS-LY
LITLTSNFF-IIIVIRLDTHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLVGLALRVQ-AISYVGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMSPTICAQLISISFVSGYFF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLISFFFITISYAYILAAILRIPSAAGQKKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QAA---MR-------NAFRGSLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NLT--EVREFVFLGFSRFC-DYQIT----LFVVFLV-LY
TLTLAGNAI-IVTIICIDRHLHT--PMYFFLSILASSDTAYT--LV--------------
T-IPR---MLSALLAQNQ-PISIAGGSAQMMF-FVALAI-NNCFLLTAMGYDCYV-AICN
PLRYTVLMSKRACVQLLCGTSGIGLVM----AVVQVTSIFTLPFCHRV-VGH-FFCDILP
-VLKLSCID-TTINEIINFVVSSCVILVPVALVFISYVIIISTILKIASTEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSED---SAEQDV--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVKIRQNLPSQ
VRTLN-------------NEI-ISEP-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-QQNVT--SWSGFVFVGFSSFG-EMQRF----LFALFFS-LY
LITLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPK---MLFGLVMGSH-AISYTGCAAQMFF-SASWAC-SNCFLLAVMGFDRYV-AICA
PLHYASHLNPTFCSQLVFASFLSGYLF----GLGMTLVIFRLSFCSSHKIQH-FFCDTPP
-MLSLACGD-TALSELGILILSLVVLLISFVFITISYICILTAILRIPSTEGRKKA----
-----F--------------STCASHFIV-VIFHYGCASFMYLRPKSS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LK-------NVFWGSLLSKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-KHQIT----LFVVFLT-VY
ILTLVANII-IVTIICIGHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHNQ-PISLAGCATQMFF-FVILAT-NNCFLLTAMGYDRYV-AICR
PLRYTVIMSKGLCAQLVSGSFGIGLTM----AVLHVTAMFNLPFCGTV-VDR-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVIFVPIGLIFICYVLVISSILQIASAEGQKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SIEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------LKCQESSIVGV-KL--R-CLCLVYNIHT----DYSI----RFLPTPT-LD
LDWLAANVS-IMVAIKLSHNLHV--PMYFFLCSLSFSETCTA--MG--------------
I-IPR---MLADLLSETK-MISLPECATQMFF-FFGLGA-NNCFILAAMSYDRYI-AIHN
PLRYHILMTRESSFQMMMASFVTGILV----SLCIVNIVFNLSFCDSHIIQH-FFCDITP
-VVSLACDY-TFLQKMALLALTAFVLMGSFFFIMISYVFILSVVVKMTSAKGQYRA----
-----F--------------STCFSHLTV-VCIHYGFACFVYLRPKNN---DSFGEDM--
-LIALTYTVL-TPML----NPIVYSLRNKEM---QVA---LRK------VIDKVSSFIHY
SV-NKRLEPLRN-ISSFDKC-----------

----------------------MERINETMVREFVFLGFSTLASLQ--RLLFVVFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLAEKKTISFL
GCAIQMFTFLFLGCSHSFLLVAMGYDRYVAICKPLHYTVLMGHGVCVGLVFVACVCGFTA
SVVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASYHSRLSQLVIFMLGVFVLVIPLILIL
ISYVYIISAILK-ITSSVGRYKAFSTCASHLIVVIVHYGCASFIYLRPKTNYSSSQDTLI
SVSYTILTPLFNPL-IYSLRNKEFKSALQRTLGQTSSSIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------KQQANRTW--LVTEFILVGFSNLP-DLRTM----LFTLFFL-TY
LVTISGNIT-IITIIHVDRTLHT--PMYRFLVVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISITGCWAQMFF-FLGLGC-SQCFLLTLMGYDRYV-AICH
PLRYSMIMRSTICFWLGALGFCSGFCV----ALIETTMIFSSPFCHSNRVEH-FFCDIAP
-VLKLSCTK-SASKALVIFFLSILVVLVSFLLILLSYAFIVAAIVRIPSAAGRHKA----
-----I--------------STCAAHLTV-VIVHFGCASIIYLRPESGG-N--RDQNC--
-LVAVFYTVV-TPLM----NPVVYTLRNKEV---RVA---LRR------NLARSCESQS-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVILAENLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFNCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPTLMSWQVCGKLTAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VILLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLSV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------PWKQLPLENFT--MVTEFLLLGFSNLN-KMQFV----LFGVILC-LY
LIILSGNIT-VITTICLEHSLHT--PMYFFLSVLSVSETGYT--LV--------------
V-LPK---MLLNLLSVLR-TISFTSCVAQMFF-LLGFGT-TNCLLLGVMGYDRYT-AICH
PLRYPVLMSWWICKLMATTCGVSGILV----SIFVTFLVFSLPFCNSNRINH-YYCDIAP
-VIRLACGD-PYINEAIILIAGIVVLVVPWMFICITYGFIIRTILRIPTTEGKKKA----
-----F--------------STCASHLIV-VVFHYGCASFVYLRPSSKH-T--SDKDK--
-LVTVTYTIV-TPLL----NPMVYTLRNREF---RVA---IQK------IWF-RCYCL--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-AQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLVDMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYM-AICH
PLRYNVLMSTRDCARLVSCCWAGGSVM----GMMLILIIFHLTFCGSNVIHH-FLCHVFS
-LLKLACGKETASVSMAVILLCVTALMGCLFLIFLSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------NFRRTFCPLTS
-------------------------------

----------------------MEWINDTMVRDFVFLGFSALASLQ--RLLFVIFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLAEKKTISFL
GCAIQMFTFLFLGCSHSFLLVAMGYDRYVAICKPLHYTVLMGHGVCVGLVFVACVCGFTV
SVVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASYHSRLSQLVIFMLGVFVLVIPLILIL
ISYVYIILAILK-ITSSVGRYKAFSTCASHLIVVIVHYGCASFIYLRPKTNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRTLGQTSSSIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------RLTILSPML-RPNST--AVSDFTFEGFSSFRWQHRLI----LFVVFLS-LY
FLTLTGNGI-IVTIIRLDRHLHI--PMYFFLSALSISETCYT--LA--------------
I-IPR---MLAGLLSPHQ-PITIPECATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKSACIQLVGGSWGIGLGM----AIIQVTSVFGLPFCGASVISH-FFCDVRP
-LLKLACVD-TAVNEIINFIVSVCVLVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSHS---SLEQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LRR------ALGCKVDSRNH
LR-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHT--STSEFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSQRSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICR
PLRYNVLMSPRGGACLVGCSWAGGSVM----GMVVTTAIFQLTFCGSHEIQH-FLCHVPP
-LLKLACGNNVPAVALGVGFVCITALLGCFLLILLSYAFIVATILKIPSAEGRNKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGPH---SQEGDT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KVA---MRK------TFLSKLYSSGT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MAVTL-GLNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LVTLLGNLL-IMATIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSALH-SIALLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FTCHVPP
-LLKLACGENVLEVAKGVETVCITALLGCFLLILLSYAFIVATILKIPSSEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--HVTMFTFQGFSSFH-EHQIT----LFAVFLT-LY
IMTLASNVI-IVTIIYIDCHLHT--PMYFFLSILSTSETLYT--LV--------------
I-IPR---MLSSLIGWNQ-SISLEGCATQMFF-FVTLAI-NNCFLLTAMGYDRYV-AICN
PLRYMIVMNKKVCAYLVGGACVIGLTI----ATIQVTSIFSMPFCEAE-VAH-FYCDIRP
-MMKLACID-TTINEIITFIISLGVILVPMGLVFISYILIISAILKITSAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SIEQDR--
-LLSITY-----------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MR-HTNVT--YWRGFLFLGFSSFG-ELQLL----LFVLFLS-LY
LVTLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGSQ-AISHVGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICV
PLHYASCMHPTLCAQLVGTSFLSGYLF----GLGMTLVIFHLPFCSSHEIQH-FFCDMPP
-VLSLACGD-TGLSELGILILSLLVLLVSFSLIAISYVYILAAILGIPSTEGRKKA----
-----L--------------STCASHLTV-VIVHYGCASFMYLRPKTR---YSLERDQ--
-LIAVTYTVV-TPLL----NRIVYSLRNRAV---KTA---LR-------NAFRGRLMGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVSSFLLWGFSSFP-DLQGP----LFAMIFF-SH
MTILAANVS-IMVAIKLSHNLHT--PMYFFLCALSFSETCTT--MA--------------
V-IPR---MLADLLADSK-TISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHN
PLHYPILMTHKICFRFIMASWMLGFLV----SLCIVIIVFNLSFCDS-IIEH-FFCDISP
-VVCLACDY-TFRQEMAIFVLSAFVLAGSFVFIMMSYVFIVSTVVKMPSAQGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QMA---LRK------VLGKTDRLIPQ
MVNKRKLDT----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLR------KKMPS
PLCVLSAQLSFSTG----------------AMSQKKCSTWPVPQKGEEKIMQVSTKATEK
PEQKTKAPRHRQTAPDKQWDNGTW--LVTEFVLVGFSNLP-ELRPT----LFTLFLL-TY
LVTLSGNAT-IITIIQVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISISGCRAQMFF-FLLLGC-NNCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLYMGILIFCSGFSV----ALVETCMIFSSPFCGTGRVEH-FFCDIAP
-VLKLSCAE-STHKGLGIFFLSILVVLVSFLLILLSYAFIVVAILRIPSAAGRHKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPDSGA-N--PSQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRK------NLAQAAGSACF
NKT-RLS------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GLNRT--SVTEFVLVGFSAFPRQLLPA----FFLLFLL-MY
LSTLLGNLL-ITATVWGERGLHT--PMYLLLCALSVSEVLYT--VA--------------
V-IPR---MLADLLAARR-AIGLPACAGQMFS-SFTFGF-AHSFLLTAMGYDRYV-AICR
PLRYHALMSPRGCARLVGCSWAGGSVM----GTVVTTAVFQLTFCGPNEIQH-FFCHVPP
-LLKLACGRDVPRVAAGVGLVCITALLGCCLLILLSYAFIVATVLKIPSAEGRRKA----
-----F--------------STCASHLIV-VVVHYGFASVIYLKPKGPH---SQAGDI--
-LMATTYTVL-TPFL----SPHQS----------------LHK------TFLSKLFPKNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLCFRFGNQSMK-TENFT--LITDFVFQGFSSFL-EQQIT----LFGVFLA-LY
ILTLAGTTV-IVTIIRIDHHLNT--PMNFFLSMQSTSETVYT--LV--------------
I-LPR---MLSSLVGMNQ-TISLAG----------------------SMGYDCYV-AICN
PLRYTVIMNRRVRIQLVLGACSIGLIV----AITQVTSVCRLLFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVV-------SL-----------------------
------------------------------------------------------------
-----------------------------EV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-AANHT--EVREFVFQGFSNFQ-EHQLT----LFVVFLT-LY
ILTLAGNVI-IVTIIRLDNHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLSSLVGLSQ-SISLEGCGAQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSIIMTWRVCAMLASSVCATGFSL----SLVQAVAILRLPFCNSL-IEH-FFCDVRP
-LLDLACAT-PLINDILTLIISLLAITVPATFLFISYVLIISTILKIASAEGRRKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LWR------VMGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LLFLSHFRHATMKANQS--VLKDFILVGFSSYP-HVRTF----LFVLFFG-LY
LLTLTGNLA-ILGLTWVDRSLHT--PMYLFLRALSFSETCYT--LT--------------
I-IPK---MLADLLTEKR-SISVPGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICH
PLRYPLLMTNVVCGQLVVSAWAGGFLI----SVTETALIFGGSFCNPNLIHH-FFCHMRA
-VVRLSCLD-SDLTELVVTMVSVSGLMGTFLLIVTTYIFILSTVFRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHFGFAAIVYLKPEGS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNRDM---KNA---FRK------LLAKRSFWNT-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFI-LGFSSLG-KHQIT----ISGVFLT-VC
ILTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEMVYT--LV--------------
I-VPR---LLCSLIFHNQ-RISLAGYATQMFF-FVILAI-NNCFLLTAMGYDCYV-AVCR
PLRYTVIISKGLCAQLVCGSFGI---------VLHVTAMFSLPFCGTV-VDH-FFCDIYP
-VMKLSCID-ITIDEIINYGVS---------LIFTSYVLIISFILKIASTEGWKKT----
-----F--------------ATCASHLTV-VIVHRGCSSTTYLKPKSEN---STEQDL--
-LLSVTYTII-APLL----NPVVYSLRNKEV---KDA---LCR------VVGRTISPIYW
II-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KENHT--VVSEFVFQGFSSFH-EHQLT----LFLVFLA-LY
ILTLAGNVI-IVTIIGLDRSLHT--PMYFFLSMLSASETVYT--LI--------------
I-IPR---MLFDLIGLNK-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRFV-AICN
PLRYSVIMNKSMCIQLVRGACGTGLIV----AMIQVSAVFRLPFCATE-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILIPMGLVFISYILIISTILRIASAEGRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TKDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------AFGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------VRT----LFMVFLI-LY
ILTRAGNAI-IVTAIHKDHHLHT--PMCFFLSVLSTSETFCS--F---------------
------------LVGLSQ-SISLEGCGTQLFL-FLGFAI-TNCLLLAVIGCGRYV-AICN
PPHYSVIMNWRVCAMLAFSVSATGFSL----SMVQAVAISRLPFCKAL-IEH-FFPHVQP
-VLNLACAT-PIINDILTLIISLLAITGPATFLFIPYILIISTILKIASVEGRKKA----
-----F--------------ATCASHLAV-VIVHSGCASIAYFKPKSEN---SKDEDQ--
-LISVTYTVI-TPLL----NPAVYSLRNKEV---QDT---LQR------VVSRNPFPKMR
SLPK---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------P-GQNWS--TVTEFILIGFSTFPQHLLPI----FFFLYLL-MY
LFTLLGNLL-IMATIWSEHSLHT--PTYLFLCALSISEILFT--VA--------------
V-TPR---MLVDMLSTHH-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLCYNVLMGTQGCASLVFWSWAGGSVM----GMMVTLIVFHLTFCGSNMIHH-FACHVLP
-LLKLSCGRETSSVTLGVILVCVTALLGCLFLTFLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SAIIFSLRNKEL---KNA---IKK------SFFRKVCPVSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVSTFLLWGFSTFP-EVQDL----LFVVIFI-SH
LTILLANMS-IMVAIKLNHSLHT--PMYFFLFGLSLSETCTT--MV--------------
I-LPR---TLVDLLSESK-TISLTECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLQYPIFMTRKICFQLMVASCVVGFLI----SLSIVFIVFNLSFCHSTTIQH-FFCDISP
-VVHLACDY-TSYHAMAIFVLSAFVLVGSFVLIMISYIFIVTVVVKMPSAKGRYKT----
-----F--------------STCSSHLTV-VSMHYGFAGFVYLRPKSS---DAFFEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QMA---LRK------VLGSAIKNFPQ
LTSKKHLN-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------PSHLTSSMK-TANHT--EVRGFVFQGFSNFR-EHQLI----LFAVFLT-LY
LLTLAGNVI-IVTIIRVDHHLHT--PMYFFLSVLSTSETCYS--LV--------------
I-IPR---MLSGLVGLSQ-SISLVGCGTQLFF-FLGFAI-TNCLLLAVMGFDRYV-AICN
PLRYPIVMNWRACTILASSVCASGFLL----SLVQAVAIFRLPFCNSL-IEH-FFCDVRP
-VLDLACVT-PIVNDILTLTISLLAITAPATFLLISYFLIISTILKIASAEGRKKA----
-----F--------------ATCSSHLTV-VIIHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRR------VVGRKSLP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MMKINQT--VLQEFILVGFSVYP-HVQTF----LFLFFFC-LY
VLTLTGNLA-ILGLTWLDRSLHT--PMYLFLSALSFSETCYT--LA--------------
I-VPK---MLADLLAKTS-RISVTGCGFQMCF-FLGLGG-TNCIILTLMGYDRFM-AICN
PLKYPLLMTNIVCGQLVASAWAGGFFI----SLVETALVFRGSFCRPNLVKH-FFCHMRA
-VMRLSCID-SDLTEFIVTVISVSGLLGTFLLIFLTYVLILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYMKPEAS-----GGDDT--
-LIAVPYTVI-TPFL----SPVIFSLRNKDM---KNA---FRK------VVGKTAALKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANHS--TVTQFILVSFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCTLSVSEILYT--VA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSLRGCAYLVGCSWAGGSVM----GMVVTSAIFHLTFCGPNEIHH-FFCHVPP
-LLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFFSKLYPEKN
V---M-I------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GLNHT--SMSEFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHM--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLCYNVLMSPRGCTCLVGCSWAGGSVM----GMVVTSAIFHLTFCGPNEVHH-FFCHVPP
-LLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TCFTKLFPQNC
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYS--LVSEFFLIGFSTFPH-LQLM----FFLLFLF-MY
LFTLLGNLL-IMATIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNELMSPGGCACLVAGSWVGGSLM----GTLVTTAIFSLTFCGPNEIHH-FFCHVPP
-LLKLACGENVLEVAKGLGMVCITALLGCFLLILLSYAFIVAAILKIPSAEGRQKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPH---SEEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KVT---MKK------AATTTHPGCSG
T---Y--FVDQAGLTLTEICLLLPPKWLD--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------TVSEFILISFSHFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIRREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLADMLSTHR-SITFVACACQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSCCWAGGSVM----GMMVTLIVFHLTFCGSNKIYH-FACHVLA
-LLKLACGKETASVTMGVILVCVTALMGCLFFIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPH---SMESNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------NFHRKFSSLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MMINQT--ILKEFILVGFSVYP-HVQTC----LFVVFLC-LY
IVTLAGNLT-IMGLTWVERSLHT--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLDKDS-HISVTGCGLQMCF-FLGLGG-THCILLTVMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVPFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFTVTLMSVSGLLGTFLLILLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASVVYLKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDI---KNA---FRK------ITRKTIVLKT-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GLNRT--STSEFILASFSTFPQQLLPV----FFLLFLL-MY
LFMLLGSLL-IMATVWSERSLHK--PMYLFLCALSISEVLYT--VA--------------
I-IPR---MLADLLSAHR-SITLPACASQMFS-SFMFGF-THSFLLTVMGYDCYV-AICH
PLRYHVLMSPRGCACLVGWSWAGGFTV----GMVVTTAIFQLTFCGSHEIQH-FLCHVPP
-LLKLACGHNVPAVALGVGVVCITAQLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVICLKPKGPH---SQEGDT--
-LTATTYTVL-TPFL----SPIIFSLRNKEL---KVA---LKK------TFLGKLRSSGT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSGFPQQLLPV----LFL-------
--------------------LHI--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHH-SITFVSCASQMFF-SFMFGF-THSFLLMVTGYDRYV-AICP
PLRYNVLMSPRDCARLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FACHVLS
-LLKL-----TSSVMMGVMLVCVTALIGCLLLIILSYVFTVAAILRIPCAEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFPSLFYLKPKGFH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKKL---KNA---INK------NFYRKFCLLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------FHQ-IM
IIAYDFLIIFFSFVKFKTMSINKT--LLEEFILVGFSIYP-DWQVV----LFVTFIF-LY
LLTLTGNLA-IMAITWMDHTLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLAKDR-SISIPGCGLQMCF-FLGLGG-TNCVILTVMGLDRFL-AICN
PLRYPIFMTNKVCGQLVASAWIGGFFI----SLTETTLIFWGSFCGPNFIKH-FFCHMRA
-VIKLSCQN-RDITEVVITIIPVSGLLGTFLFIVLTYVFILSTVLKIPSAEGRKKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAE-----EGDDT--
-LMSVPYTVV-TPFL----SPLIFTLRNKDM---KNA---LKK------VLDKKFSL---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANQT--EVKEFVFQGFSNFQ-EHQLI----LFVVFLS-LY
ILTLAGNLI-IVTVIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLSSLVGRSQ-SISLEGCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLCYSIVMNWRVCVILASSVCATGFSL----SLIQAMAIFRLPFCDSL-IEH-FFCDVRP
-MLDLACVT-PIINDVLTLIISLLAITAPATFLFISYILIISTILQIASAEGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-KPLL----NPIVYSLRNKEV---QDA---LWR------VMGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LPLKNLT--TVTEFLLLGFSNLQ-DLQLV----LFAIFLC-LY
IIILCGNIT-IVTVILLEHSLHI--PMYFFLGVLSVSETCYT--FV--------------
I-LPK---MLLNLLSVLR-TISFTSCAIQMFF-FLSFAI-NNCLLLGVMGYDRYA-AICH
PLRYPILMNWRACRLLAATCGLSGFLI----SMVGTTLVFILPFCNSNKIRH-YFCDISP
-VIHLACGN-TYINEMIIFICGVLVLVVPLIFICFSYVFIVSTILRIPSTEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSSKV-S--SGKDQ--
-LVTVTYTIV-TPLL----NPMVYSLRNRDV---QMA---IRK------EATSEVIFEHE
ILEI---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ME-QTNAT--FQRGFVLLAFSSFG-ELQLL----LFALFLS-LY
LVTLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLAFSETCYT--LG--------------
I-IPR---MLSGLVRGGR-GISYVGCAVQMFF-SASWAC-SNCFLLAAMGFDRYV-AICA
PLHYANRMNLTLCAQLVGTSFLSGYLF----GLGMTLVIFHLPFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLLSFCLISTSYTYILAAILRISSTEGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIIYSLRNRAV---QTA---LR-------NAFQGGLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
LP-PSPHSSLQIIPWERFSSENLT--TVNEFLLLGFSSLQ-EKQLV----LFPIFLC-LY
LLILCGNII-IVTVICLEHSLHI--PMYFFLGVLSVSETCYT--FV--------------
V-LPK---MLINLFSVLR-TISFTSCAIQMFF-FLGFGV-TNCLLLGVMGYDRYA-AICH
PLRYPILMNWRVCRLLAASCGVSGFLI----SLIGTTLVFILPFCNSNKVEH-YFCDISP
-VIHLACGD-AHINELIIFICGILVLVFPLSFICISYGFIISTILKIPSAEGKRKA----
-----F--------------STCASHLTV-VVVHYGCASFVYLRPTSRI-T--SSKDQ--
-LVTVTYTIV-TPLL----NPMVYSLRNRDV---QLA---IRK------VISWE------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------YVFLPEVTMRINQT--FLEEFILIGFSVYP-DWQVV----FFVFFFF-LY
LLTLIGNLA-IMALTWVDHSLHT--PMYLFLGALSFSETCYT--LA--------------
I-IPK---MLVDLLAKDR-SISIPGCGLQMCF-FLGLGG-TNCIILTVMGLDRFL-AICN
PLRYPTLMTNKACGQLVALAWICGFFI----SLTETTLIFWGSFCGSNLIRH-FFCHMRA
-VVKLSCLN-SDITEVVVTVISVSGLLGTFLFIILTYVFILSTVLKIPSAEGRKKA----
-----F--------------STCASHLTV-VIIHFGFASIV-------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------SQKE---VIQMQGFNRTA--VVTQFILVGFSSLE-ELQVL----LFVIFLL-LY
LTILMANAI-IMTVICFSRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSATK-TISFIACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMSKRLGLGLVSLSTVTGFFI----ALVATNLICGMHFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMMPFLLILVSYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLQPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNKEV---KTA---LKR------VLGMPVAT---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKINRT--ILKEFVLVGFSVYP-YAHTF----LSVVFFC-LY
LLTLTGNLA-IMYLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-TPK---MLADLLAKNR-SITIIGCGLQMCF-FLGLGG-TNCVILTLMGFDRFL-AICN
PLRYPLLMTNVVCGQLVVSAWVAGFII----SVTETTLIFRGSFCGPNLVKH-FFCHMRA
-VVRLSCLD-SELTELIVTAISVSGLMGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPGAS-----GGDDT--
-VIAVPYTVI-TPFL----SPLIFSLRNKDM---KDA---FRK------VLGKTSSLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNLT--EVTEFIFLGFSRFH-EHQIT----LFVVFLI-LY
TLTLAGNAI-IVTIIHMDRHLHT--PMYFFLSMLASSETMYT--LV--------------
I-IPR---MLTGLIAQNQ-PISLAGCTTQMFF-FVTLAI-NNCFLLTVMGYDRYV-AICN
PLRYMVIMSKRVCVQLMCGAFGIGLAM----AAVQVTSIFTLPFCHRV-VGH-FFCDILP
-VMKLSCID-TTINEIINFVVSLFVILVPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SVEQDL--
-LLSVTYTIV-TPLL----NPVVYSLRNKEV---KEA---LCR------AVSKNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RVSHT--ELREFVFQGFSSFQ-EHQLI----LFVVFLT-LY
ILTLAGNII-ILAIIYVDHHLHM--PMYFFLSVLSTSETFYP--LV--------------
T-IPC---MLSSLV----------------GL------S-QSISLEAVMGYDRYV-AICN
PLGYSVIMNWKVCAILASSVCATGFSL----SLVQTVAIFRLPFCSPL-IEH-FFCDIWP
-VLDLACAT-PVTSDILTLIISLLAITAPVTFLFNSYVLIISTILKITSAGGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKLKLEN---TKDQDQ--
-LISVTHTVI-TPLL----NSVVYSLRNKEV---QDA---LQR------VLGRKFFC---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GVNHS--GVSEFILIGFSTFPH-LQLM----FFLLFLF-MY
LFTLLGNLL-IMATIWSDHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPSGCACLVAGSWVGGSLM----GTLVTTAIFNLTFCGPNEIHH-FVCHVPP
-LLKLACGENVLVVARGVGMVCITGLLGCFLLILLSYAFIVAAILKIPSAEGRQKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MT-GQNYS--TTSEFILFSFSAFPHQLLLA----LFLLYLL-MY
LFTLLGNLL-IMATVWTERQLHT--PMYTFLCALSISEILLT--IT--------------
I-TPR---MLGDLLSTNH-SITFVACAAQTFC-SFTFGY-AHSFLLMVMGYDRYV-AICH
PLRYNVFMSPTVCAHLVAWSWAGGSAV----GMIMTSIVFHLTFCESHVIHH-IFCHVFS
-LLKLACGDEMGSVTIGVILVCVIPLISNLILIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHNSFASMIYLKPKGPY---SVYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNS---INK------Y-YRKLCLQNP
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-HTNVT--YWRGFRFLGFSSYG-QLQLL----LFVLFLS-LY
LITLTSNVF-IIVVIRLDSRLHT--PMYLFLSFLSLSETCYT--LG--------------
I-IPR---MLSGLAMGDQ-AISYEGCAAQMFF-SASWAS-TNCFLLAVMGFDRYV-AICV
PLHYVSCMHPTLCAQLVATSFLCGYLF----GLGMTLVIFHLPFCNSHEIQH-FFCDTPP
-VLSLVCGD-TGLSELVILVLSLLVLLVSFSLITLSYAYILAAILKIPSAEGRKKA----
-----F--------------STCTSHLTV-VIIHYGCASFMYLRPKMS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LK-------NAFQGRLMGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-RHQIT----LFVVFLT-IY
ILTLTGNVI-IVTITLMDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICD
PLRYMVIMSKGMCAWLVCASLGMGLVM----AVLHVPAMFSLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTLNEIINYGVSSFVILVPIGLIFISYVLIISSILKIASAEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRKTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLCFRFGNQSMK-TENFT--LITDFVFQGFSSFH-EQQIT----LFGVFLA-LY
ILTLAGNTI-IVTIIRIDHHLNT--PINFFLSMLSTSETVYT--LV--------------
I-LPR---ILSSLIGMNQ-PISLAG----------------------SMGYDCYV-AICN
PLRYMIIMNKRVHIQLVLGACSIGLIV----AITQVTSVCRLPFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVE----G-R-K
-K-A-F-A-------------TCASHLTV-VTIHY-------------------------
----VTYTVI-TPLL----NPVVYTLRNKEV---KDA---LSR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
APLNLIC-----YQPSTK-TTNHT--EVREFVFQGFSSFH-EHQLT----LFVVFLA-LY
LFTLAGNII-IVTIIGLDRHLHT--PMYFFLSMLSVSETVYT--LV--------------
I-IPR---MLLNLLGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRCV-AICN
PLRYSVIMSKRLCIQLVWGACSIGLTV----ATTQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLVISVLVILIPMGLVFISYILIISTILKMASAEGRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KNA---LCR------AIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MKRINQTT--RVTKFILVGFSSLG-ELQML----LFVIFLL-LY
MTILLANAT-IMTVIRCSRSLHT--PMYGFLFILSFSETCYT--FV--------------
I-IPQ---LLAHLLSITK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICY
PLRYMIIMNKRLGLGLISVSGATGFFI----ALVATNLICEMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVKTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VIVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KEA---LKK------VFWRPVSAKLI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYS--FVSEFILIGFTTFPH-LQLM----FFLLFLL-MY
LFTLLGNLF-IMATIWSERSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SITFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLIFCGPNEIHH-FFCHVPP
-LLKLACGENVLEVAKGVGMVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVT---MKK------AFLNKLFLQ--
----------NS-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-SQNYS--IISEFNLFGFSAFPQHLLPI----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCTLSVSEILFT--VA--------------
I-TPR---MLADLLSTHH-SITFVACANQMFF-SFMFGF-THSFLLLVMGYDRYV-AICH
PLRYNVLMSPRDCAHLVACTWAGGSVM----GMMVTTIVFHLTFCGSNVIHH-FFCHVLS
-LLKLACENKTSSVIMGVMLVCVTALIGCLFLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFASFIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFYRKFCPPSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANTS--CVTEFLLLGFSSLG-ELQLV----LFVVFLF-LY
LIILSGNVT-IISVIFSDHSLHT--PMYFFLGILSTSEIFYT--MV--------------
I-LPK---MLINLLSVFR-TLSFVSCATQMFF-FFGFAI-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCGQLAATCMVSGFLI----SLMGTTLIFSLPFCGSSRVNH-YFCDISP
-VIRLASAE-SYIYELVIFICGVLVLVMPLIFICISYGFIVHTILKIPSAEGKQKA----
-----F--------------STCASHLIV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-QNNAT--CWRGFVFLGFSSFG-DLQLL----LFVLFLS-LY
LVTITSNIF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTLCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLITVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QSA---LK-------NALRGSLLGKG
RK-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LP-GQNYS--TISEFILFGFSDFPQQLLPI----LFLLYLL-MF
LFTLLGNLL-IITTIWIEHRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHR-SVTFVACASQMFF-SFTFGF-THSFLLMVMGYDHYV-AICH
PLRYSVLMSPCDCAHLVAWTWAGGSVM----GMMVTMIVFHLSFCGSNVIHHNFACRVLP
-LLKLACGNKTSSVIMGLMLVCVTALISCLLLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------CTGVSHLTV-VVVHYSFASLIYLKPKGLH---SMYSDA--
-LMATIYTVF-TPFL----SPIIFAVRNKEL---KNA---INK------NF---------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--DVTEFIFLGFSSFG-KHQIT----LFVVFLT-IY
ILTLAGNII-IVTITYMDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICD
PLRYMVIMSKGMCAWLVCGSLGTGLVM----AVLHVPAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCID-TTLNEIINYGVSSFVILVPIGMIFISYVLIISSILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYIII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNAS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------VSPDAAFSS-GQNHS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTIWREHSLHT--PMYLFLCALSTSEILFT--VT--------------
V-TPR---MLVDMLSTYR-SISFTACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWSWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FLCHVLS
-LLKLACGNETSSVTLGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VIVHYGFASIIYLKPKGPR---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFHRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MVSEFILIGFSTFPR-LQGF----FFVLFLL-MY
LSTLLGTLL-IIVTVQNERKLHT--PMYCYLCTLSLSEIFYT--FA--------------
I-IPK---MLSDLLSTQR-TISFLGCANQMFF-SFTFGF-THSFLLTTMGYDRYV-AICY
PLRYSVLMKPQICIWLLVSSCLGGLVM----GLVVTVAVFHLSFCGPNEIHH-FACHMLP
-IVKLACGD-VSLTALAVGVLCIIVLMSCFLLILLSYAFIVATIMKIPSAEGRLRT----
-----F--------------STCAAHLTV-VVVHYGFASIIFFKPKT-H---VLEGDS--
-LMAVTYTVF-TPFL----SPIIFSLRNKEL---KNA---LKK------TFKNGLFPHTK
K------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKKFM--EVTEFVFLGLA-----------------TCN-HL
ILTMAGNII-SLTTTCIDLHLQI--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MIWGFIFHKQ-LIFLAGCSTQMLF-FVTLAT-NSYFLLTDGL----------
-------------WLLLCGSFGICLVM----AVLHVTSMFILPFCDNV-VDH-FFCDIYP
-VMKLPCVD-TTVTEIINYGVSSFLILVPIGLIWISYVFIISSILKIASTEGQMKA----
-----F--------------ATYASHLTV-VIVHCGCTPITYLKPKSES---SVEKDF--
-LFSVTCTII-TPLL-----------RDKEV---KDA---LCR------AMGRNVS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-SKNDT--GVSEFILQGFSSFR-EHKII----LFVIFLT-LY
LLTLAGNVI-IVTVISFARHLHT--PMYFFLSVLSTSETVYT--LV--------------
I-VPR---MLCSLTGLNQ-PISLAGCATQMFL-FLTLAI-NNCFLLTAMGYHRYV-AICN
PLRYTVLISKRVCALLVWGAFSIGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDILP
-VMKLSCAD-TTLHDIINFIISSLVILVPMGLVFISYVLIISTILKIPSAQGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SRDQDQ--
-LISVTYTVI-TPLL----NPVVYRLRNKEV---KDA---LHR------AVGRNPLV---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MM-RRNHT--VVNEFVFQGFSSFQ-EYKFT----LFMIFLT-LY
LLTLTGNVI-IVIIISIDRHLHT--PMYFFLSTLSTSETVYT--LV--------------
I-VPR---MLSSLVGSSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCAQLVWGSCSIGLLV----AIIQIASVFRAPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIINFIISSLVIVVPMGLVFISYIIIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKKNLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------RESKFVSQSFSSFQ-EHQLT----LFMVFLA-LY
ILTLAGSII-IVTIIHTDHHLHT--PMHFFLSVLSTSETLYS--LV--------------
I-IPR---MLSSLVGLSQ-SISLECCGTQLFF-FLGFAL-TNCLLLAVLGYDHYV-AMCN
PLHYSTIMNWRVCTMLASSMCATGFLI----SLVQ---------------AH-FLCDVRP
-ILDLACAA-RIIDDILTLIISLLAITASAIFLFISYVLIISTILNIASAEGRKKT----
-----F--------------AACVSHLTV-AIIHYGCASIAYFKPKSEN---SKDQDQ--
-LISVTYRVI-TPLL----HPVGYSLRNEEV---QDT---LCR------EVVRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------LLFFFSLQVLAENLT--VVTEFLLLGFSSLG-EIQLA----LFVVFLI-LY
LLILSGNAT-IISVIHLDQTLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-TISFTCCAIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPLLMSWHVCGKLAAACGIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVHEFVIFICGVCVLVVPFFFICVSYLCILRTILKIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IQK------MLGKKGS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LSMANSS--CVTEFLLLGFSSFG-EFQLV----LFVVFLC-LY
LIILSGNIT-IISVIRLDHSLHT--PMYFFLCVLSTSEIFYT--IV--------------
I-LPK---MLINLLSILR-TLSFMSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLYYPILMSWKVCGQLVAICIVSGFLI----SLVGTSLVFSLPFCDSNKINH-YFCDISP
-VIRLACAE-TYINELIIFICGVLVLIVPLIFICISYGFILRTILKIPSAEGKRKA----
-----F--------------STCASHLIV-VIVHYGCASFVYLRPSARY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------MIGKTGFP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-HHQMT----LFAVFLT-IY
ILTLAGNIT-IVTIACMDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHNL-AISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICD
PLRYMVIMSKGMCAWLVCGSLGTGLVM----AVLHVPAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTLNEIINYGVSSFVILVPIGLIFISYVLIISSILKIASTEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RTNFT--VVTKFTFEGFSIFGWHHRLI----LFVAFLI-LY
LLTLASNAI-ILTVIHLNRQLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPR---MLSSLLNPEQ-AISIPECASQLFF-YLTFGV-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKACLQLAGGSWIIGLST----AIIQVSSVFSLPFCDANVISH-FFCDIRP
-LMKLACAD-TTIKEFITLLISLYVLVLPMVLIFISYVLIVTAIFKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDS---LLR------VLGKKKPSL--
-------------------------------

-------------------MLFVQTVNETMVREFVFLAFSSLASLQ--RLLFVIFLLIYL
FTLGTNAII-IATIVLDGALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLAEKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTALMGGGVCVALVAAACACGFMV
AQIITSLVFDLPFHSSNLLHHFFCDISPVLKLATHHSHLSQLVIFMLGVFVLIIPLLLIL
ISYVRIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKTNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQKTMRQASCPIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MIPSANLT--MVTEFLLLGFSNLQ-EKQLI----LFPVFLC-LY
LLILSGNIT-TVTAIRLEHRLHT--PMYYFLTVLSVSETFYT--IV--------------
I-LPK---MLLNLLSVLR-TISFTNCAVQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICH
PLRYPVLMSWRVCGQLSVFCGIAGFLL----SLIMVNLVFSLPFCNSNKINH-YFCDISP
-VIRLACTD-SDTHEFVIFILGALVLVVPFSFICISYISILRTILKIPSMEGKKKA----
-----F--------------STCASHLTV-VIIHYGCASFIYLRPTASY-I--SNKDR--
-LVTVTYTIV-TPLL----NPIVYSLRNKDV---QLA---IRK------VLMKLNCVSVS
DTI----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------LGNLT--MVTEFLLLGFSDFQ-EMQFA----LFAVILC-LY
LVILGGNIT-IITIIHLEHSLHT--PMYFFLGVLSVSETFYT--LV--------------
I-LPK---MLLNLLSVLR-TISFVSCATQMFF-FLGFAI-TNCLLLGVMGYDRFT-AICY
PLRYPVLMSWWLCKLMAATCGASGFLI----SMVGTFLVFSLPFCSSNRVNH-YFCDIAP
-VIHLACGD-PYINEVIIFIGGVVILMVPLTFICITYGFIVRTILRIPSTEGKKKA----
-----F--------------STCASHLTV-VVVHYGC-----------------------
------------------------------------------------------------
-------------------------------

----------------------MSRENCTTMSEFILLGFSHLGGSQ--RPLFGLFLLLYL
VTLGTNMVI-VTTIVLDHRLHMPMYFFLATLSCSETLYTLVIIPKALVDLLAQHRAITIT
ACAFQMGSFLFLGCSHSFLLAAMGFDRYMAICRPLSYTRLMTRGVCVALVVAAFFCGSAV
SLVVTSLVFGSSSPSSSHLQHFFCDIPPVLRATSPPGSQRRVVILALCSLVLVIPLFLIA
ASYACIVATILH-IPSSGGRVKPFSTCASHLIVVTVHYACASFIYLRPGAGDSSGRDALV
SVTYTVVTPLLNPV-IYSLRNREFRVALYRVFERICCPALC-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRREN-QT--VPPGFAFIGFSYFP-KLQAV----LFVLFLL-MH
VVTLVGNIM-IMFVIRLNQQLHM--PMYFFLSALSFSEICYT--FS--------------
I-IPK---MLSGLVLGTR-TISFLGCAAQMHF-SFMFGF-THSFLLTVMGYDRYV-AICQ
PLHYSTVMTSRACTQLVAASWAGGGLL----GLLVTSAVFQLPFCQSHRIDH-FFCHVPP
-ILQLACAG-GEVVGTVVGIFCITALLGCFLFILLSYAFILGWILQMPSAKGRHKA----
-----F--------------SACASHITV-VVVHYGCASVIYLKHQSP---RAAGASV--
-LIDVSYTVF-TPFL---------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTTFLLWGFSSFP-ELQNL----LFVVILL-SH
VSILLANAS-IMVAIKLNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLISKSK-AISLPECATQMFF-FFGLGG-NNCFILSAMSYDRYT-AINN
PLHYPILMTQKICLQLIIASGVLGFSV----SLCIVVTIFNLSFCNSNIIQH-FFCDIDP
-VVSLACNL-TFYHKVILFAFTAFVLVGSFIFIMVSYVFIVTVVMKMPSAKGRYKT----
-----F--------------STCSSHFTV-VFIHYGFACFVYLRPKNS---YSFKDDT--
-LLAMTYTIL-TPLL----NPIIYSLRNKSM---QTA---LRK------DIGNVIRF---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQGINRTT--VLTQFILVGFSSLE-ELQLL----LFVIFLL-LY
LTILMANAT-IMAVIRFSRTLHN--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSATK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLALVSLSGVTGFLI----ALVATNLICGMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFILNTILKIPSTEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASVIYLRPKSKS-A--SHKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KAV---LKR------VLGMPVATKVS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKKFM--EVTEFVFLGLARMS-FHFLISSLIIFFSACN-HL
ILTMAGNII-SLTTTCIDLHLQI--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MIWGFIFHKQ-LIFLAGCSTQMLF-FVTLAT-NSYFLLTDGL----------
-------------WLLLCGSFGICLVM----AVLHVTSMFILPFCDNV-VDH-FFCDIYP
-VMKLPCVD-TTVTEIINYGVSSFLILVPIGLIWISYVFIISSILKIASTEGQMKA----
-----F--------------ATYASHLTV-VIVHCGCTPITYLKPKSES---SVEKDF--
-LFSVTCTII-TPLL----NPVVYSLRDKEV---KDA---LCR------AMGRNVS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNRS--AITEFILVGFSNLG-DLQIL----LFITFLL-VY
LTTLLANAT-IMTVIRLDRDLHT--PMYFFLFVLSCSETCYT--LD--------------
I-VPK---MLTNLLVTVP-SISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRAACLQLVLASSFCGFLI----SVAVNILVFTVPFCASNRVNH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFALIFISYVFIVSTILKISSVEGQHKA----
-----F--------------ATCASHLTV-VIVHCGCASSIYLRPTSLH-S--SDKDL--
-LVAVTLYSDYSTSQ----PPCLYSEK---------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------VVPWNQLSPENVT--MVTEFLLLGFSNLQ-EMQFV----LFAVFLC-LY
LVILGGNIT-IITTVHLEHSLHT--PMYFFLSVLSVSETCYT--FA--------------
I-LPK---MLLNLLSVLR-TISFTRCVTQMFF-FLGFAI-TNCLLLGVMGYDRYT-AICH
PLRYPVLMSWWICKLMVAACGVSGFLV----SMLGTFLVFSLPFCNSNRVNH-YFCDVAP
-VIHLACGD-TYMNELVIFIGGVVVLMVPFAFICISYGFIVRTILRIPSTEGKKKA----
-----F--------------STCASHLTV-VIVHYGCASSVYLRPSSRH-I--SDKDK--
-LVTVTYTIV-TPLL----NPMVYSLRNRDV---QLA---IRK------VMSWKRFS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLMTLKVCFQLMMASAVVGFLV----SLCIVIIVFNLSFWDSNTIRH-FFCDIAP
-IASLACSY-TFFQKMVLLAFTAFVLVGSFILIMISYVFIVSLVVKMPSAKGRRKA----
-----F--------------STCSSHFTV-VSVHYGFACFVYLRPKNSD-TDSFSEDT--
-LMAVTYTVL-TPLL----NPIVHSLQNKEM---QVA---PRK------VLGSIMLIKEL
RIFNVRKE-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
LF-FLNVYSLLFCIFLTVLAENLT--MVTEFLLLGFSSLG-DIQLV----LFVVFLF-LY
LAILSGNVI-IVTVIRLDKSLHT--PMYFFLSILSTSETCYT--FV--------------
I-LPK---MLINLFSVAR-TISFHCCAIQMFF-FLGFAM-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWQMCGKLGALCGIGGFLA----SLTVVYLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDAHEFVIFICGVLVLVVPFLFICVSYICILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASYIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QVA---IRK------VLGKKGSLK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----ILLHFRFSGHSMK-RENHT--LTTEFSLQGFSSFQ-EHQLT----LFVVFLA-LY
ILTLAGNIV-IVTIIHIDHHLHT--PMYFFLSMLSTSETIYT--LV--------------
I-LPR---MLASLVGVSQ-SISLAGCATQMFL-FVTFGI-TNCFLLTAMGYDHYV-AICN
PLRYTVMMNKRVCVQLVGGACSIGLIV----AMTQVTSVFRLPFCAAK-VAH-FFCDIHP
-VMKLSCID-TTVNEILTLIISVLVLVVPMALVFISYVLIISTILKIASAEGRQKA----
-----F--------------ATCASHLTV-VVVHYGCASIAYLKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------VIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--SWRDFVFLGFSSSG-ELQLL----LFALFLS-LY
LVTLTSNVF-IIIAIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLAGGDQ-AISYVGCAAQMFF-SASWAC-TNCFLLAAMGFDRYV-AICA
PLHYASRMNPTLCAQLVITSFLTGYLF----GLGMTLVIFHLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TGPSELKIFILSLLVLLVSFFFITISYAYILAAILRIPSAEGQKKA----
-----F--------------STCASHLTV-VIIHYGCASFVYLRPKAS---YSLEIDQ--
-LIAMTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGRLLGKG
-------------------------------

--------------------LSMERANETVVKEFVFLGFSSLAGLQ--RLLFIGFLLLYL
FTLGTNAII-ISTIVLDSALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCAHSFLLAAMGYDRYVAICNPLRYTVLMGHAVCMGLVATACVCGFAV
SVVTSSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSRLSQMIIFMLGVFVLVVPLLLIL
VSYIHIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSRDSLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRAMGQMLFPAN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPQILI
FT-YLN--MFYFFPPLQILAENLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFNCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPTLMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISA
-VILLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLSV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ME-QTNAT--FWSGFIFLAFSSFG-ELQLL----LFALFLS-LY
LITLTSNVF-IIVVIRLDSCLHT--PMYLFLSFLAFSETCYT--LG--------------
I-IPR---MLSGLVRGGQ-GISFVGCAVQMFF-SASWAC-SNCFLLAAMGFDRYV-AICA
PLHYASRMNLTLCAQLVGTSFLSGYLF----GLGMTLVIFHLPFCSSHEIQH-FFCDTPP
-VLSLACGD-TALSELGILILSLLVLLVSFSLISVSYTYILATILRISSTKGQKKA----
-----F--------------STCASHLTV-VTIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIIYSLRNRAV---QTA---LR-------NAFQGGLLGKG
-------------------------------

----------------------MEWVNETTVRQFVFLGFSSLAGLQ--KLLFVVFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFR
GCAIQMFSFLFLICSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACACGFII
SLVTTSMIFHLPFHSSNQLHHFFCDVSPVLKLASHHSHLIQLVIFVLGVFVLVIPLLLIL
VSYVLIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLLNPM-IYSLRNKEFKSALRKAMVQTSYPTN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------RESKFVSQSFSSFQ-EHQLT----LFMVFLA-LY
ILTLAGSII-IVTIIHTDHHLHT--PMHFFLSVLSTSETLYS--LV--------------
I-IPR---LLSSLVGLSQ-SISLECCGTQLFF-FLGFAL-TNCLLLAVLGYDHYV-AMCN
PLHYSTIMNWRVCTMLASSMCATGFLI----SLVQ---------------AH-FLCDVRP
-ILDLACAA-RIIDDILTLIISLLAITASAIFLFISYVLIISTILNIASAEGRKKT----
-----F--------------AACVSHLTV-AIIHYGCASIAYFKPKSEN---SKDQDQ--
-LISVTYRVI-TPLL----HPVGYSLRNEEV---QDT---LCR------EVVRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GFNSS--SVSEFILLGFSAFPHQLLPV----LYLLFLM-MY
LFTLLGNLL-IMATIWRQRSLHM--PMYLFLCALSISEILYT--FA--------------
V-IPR---MLADLLATQR-SIALVACVGQMFF-AFTFGF-THSFLLTIMGYDRYL-AICH
PLRYSVLMSPRGCGCLVAWSWVGGLVM----GLVVTTAIFNLTFCGPNKVHH-FACHVPP
-LLELACGDNVPAVAMGVGLVCITALLGCFIFLLLSYIFIVVTILRIPSAEGRQKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPNGAT---SAEGDT--
-LMATTYTIL-TPFL----SPIIFSLRNKEL---KMA---MKR------TFLSELCGDKV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HS--TVTTFLLWGFSSFP-ELHNL----LFVVILL-SH
VTILLANAS-IMVAIKLNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSESK-AISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLHYHIFMTPKVCSQLVIASCVVGFLC----SLSITFTIFNLSFCDSKTIQH-FFCDISP
-LVHLACDY-TAHHAMIIFMVSAFVLVGSFVLIMISYAFIVFLVVKMPSAQGRHKA----
-----F--------------STCSSHLTV-VSMHYGFACFVYLIPKNS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLSSINKMLPC
LAIKKPEHLRTT-IEH---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MAPEKQQDNGTW--LVTEFLLVGFSNLP-ELRPT----LFILFLL-TY
LVTLSGNAT-IITIIQVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISIAGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLCLGALVFCSGFSV----ALIETCMIFSSPFCGAGHVEH-FFCDIAP
-VLKLSCDE-SSLKGLGIFFLSILVVLVSFLFILLSYAFIVAAIVRIPSASGRRKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPDSGA-N--PSQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRK------NLARGCGAFK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VLPHFRFSGYSME-KENHT--LIMEFIFQGFSSFH-EHRLT----LFAVFLV-LY
AFTLAGNVI-IVTIIRTDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-LPR---MLSSLVGMNQ-SISRAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRECFQLVGGACSIGLVV----ATTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTINEILTVIISVLVLVVPMGLVFISYVLIISSILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------AMGRNPS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RPNFT--VVTHFTFEGFSIFGWQHRLI----LFVVFLV-LY
LLTLASNAI-ILMVIRLNRQLHT--PMYFFLSVLSMSETCYT--VA--------------
I-IPR---MLSSLLSPQQ-AISIPDCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVVMGKRTCIQLASGCWSIGLST----AIIQVSSVFSLPFCDANVISH-FFCDIRP
-LMKLACAD-TTIKEFITLLISLCVLVLPMVLIFISYVLIVSTILKMASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------ALGKKPFS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ME-RENHS--WVGEFTFQGFSSFR-EHQLT----LFVVFLA-LY
ALTLTGNVI-IVSIISADRHLHT--PMYFFLSMLSASETVYT--LV--------------
I-IPK---MLCNLLGLSR-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTILMNKRVCLQLVGAACSIGLIV----AMTQVLAVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILVPMGLVFISYVLIISSILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------ATGRKPS----
-------------------------------

----------------------MEWVNETTVREFTFLGFSSLAGLQ--RLLFVVFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGYGVCVGLVAAACFCGFTV
AQIITSMVFHLPFHSSNQLHHFFCDISPVLKVASHPTHFNQFIIIMLCALVLVIPLFLIL
VSYIHIISAILQ-FPSTLGRYKAFSTCASHLIIVIVHYGCASFIYLRPKSHYSSSQDVLM
SVSYTILTPLFNPI-IYSLRNKEFKSALQRVVGRTISLLHH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MINQT--ILQEFILIGFSVYP-HVQTC----LFVVFLC-LY
MVTLAGNLA-FMGLTWADRSLHT--PMYYFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLDKDN-RISDIGCGLQMCF-FLGHGG-THCILLTLMGYDRFL-AICN
ALKYPLLMTNVACGQLVATAWVGGFFI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFIVTLMSVSGLLGTFLLILLTYVFILSSVLMIPSAEGKQKA----
-----F--------------PSCASHLTV-AIIHFVFAPVDYLKPENS-----GGDDT--
-LIAVLYTVI-TPFL----SPIIFTLRNKDM---KNA---FRK------IMRKTVVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANFS--SVTEFIFIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-ITTTIWRERSLHT--PMYLFLCALSISEVLYT--FA--------------
V-IPR---MLADLLSTHH-SIALTACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYKVLMSPHGCACLVAWSWAGGSVM----GMVVTSAIFHLTFCGSNVIHH-FVCHVSP
-LLKLACGDNVSTVATAMGLVCISALLGCCLLILLSYAFIVAAILRIPSAEGRHKS----
-----F--------------STCVSHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNT---MKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MINQT--ILKEFILIGFSAYP-LVQTW----LFVVFLC-LY
MVTLAGNLA-IMGLTWVDRSLHT--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLIDKDS-RISVTGCGLQMCF-FLGLGG-TNCILLTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFIVTLMSVSGLLGTFLLILLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VLIHFVFASVVYMKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDM---KNA---FRK------IMRKTVVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNSS--FVTEFAFEGFSSFGWRHRLV----FFVVFLT-LY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLSGLLNPHQ-TIDIHGCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKRACAQLSSGSLGIGLGM----AIVQVTSVFGLPFCDGFVISH-FFCDVRP
-LLKLACAD-TTLNEMVNLAVSVCVLVLPMGLVFVSYVLIISTILKIASAEGRQKA----
-----F--------------ATCASHLTV-VIVHYSCASVVYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGRKPLSP--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PENLT--MVTEFLLLGFSSLQ-ELQLV----LFAVFFC-LY
IIILCGNIT-IVTVILLEHNLHT--PMYFFLGVLSVSETCYT--FV--------------
I-LPK---MLLNLLSLFR-TISFTSCAIQMFF-FLSFAI-NNALLLGVMGYDRYA-AICH
PLRYPVLMNWGTCRLLAATCGVSGFLM----GMVGANLVFTLPFCNSNKVNH-YFCDISP
-LIHLACGD-THVNEMTIFICGVLVLVVPLLFVCISYGFIVRTILRIPSTEGKQKA----
-----F--------------STCASHLTV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PENLT--MVTEFLLLGFSSLQ-ELQLV----LFAVFFC-LY
IIILCGNIT-IVTVILLEHNLHT--PMYFFLGVLSVSEICYT--FV--------------
I-LPK---MLLNLLSLFR-TISFTSCAIQMFF-SLSFAI-NNALLLGVMGYDRYA-AICH
PLRYPVLMNWGTCRLLAATCGVSGFLI----SMVATTLVFILPFCNSNKVNH-YLCDISP
-LIHLACGD-THVNEMIIFIFGVLVLVVPLLFVCISYGFIVRTILRIPSTEGKQKA----
-----F--------------STCASHLTV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KANCT--HVREFVFQGFSNFQ-EHQVT----LFIVFFV-LY
ILTLTGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCRTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSIIMNWRVCIILASSVGATGFLL----SLIQAVAIFRLPFCNTL-IEH-FFCDVRP
-ILDLACTV-PVINDILTLALSLMVITAPATFLFVSYVLIISTILKIASAEGRRKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLGKKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTDLIFLGFSIFG-KHQLT----LFVVFLT-VY
ILTLTSNVI-IVTIIRVDRHLHT--PMYFLLSMLASSETVYT--LV--------------
I-VPR---MLSSLLFHNQ-PISLAGCATQMFF-FVTLAT-SNCFLLTAMGYDRYL-AICS
PLWYTVLMSKGVCATLVCGSFGTGLAM----AVLHVAAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTINEMINYAVSSFVILVPVGLIFISYVFIISAILKIASAEGRKKA----
-----F--------------ATCTSHLTV-VIVHYGCASIAYLKPKSEN---SIEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGKNIITDR-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILFGFSAFPHQMLPA----LFLLYLL-MY
LFTLLGNLV-IMAAIWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLSDMLSTHR-SITFIACANQLFF-SFTFGY-THSFLLVVMGYDRYV-AICR
PLHYHALMSLQGCARLVAWSWAGGSLI----GMALTIIIFHLTFCESNVIHH-ILCHVFS
-LLKLACGERTAFVTIAVILVCVTPLIGCLVFIILSYIFIVAAILRIPSTEGRHKT----
-----F--------------STCASHLTV-VIVHYGFASIIYLKSRGLY---SQYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---IIK------SFHRNVCQQSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-KHQIT----LFVVFLT-IY
ILTLAGNII-IVSITYTDHHLHT--PMYFFLSMLASSEIMYT--LV--------------
I-VPR---MLSSLIFDNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICE
PLRYAIIMSKGMCALLVCGSLGTGLVM----AVLHVPAMFHLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTVNEIINYGVSSFVILVPIGLIFISYALIVSSILKIVSAEGQKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LSQTHSQKD---VIQMHSFNRTT--VVTQFVLVGFSRLG-ELQLL----LFVIFLL-LY
LTILLANAT-IMAVIRCSRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLAHLLSATK-TVSFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGWGVVSLSGVTGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACID-SHVKELALFGLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASVIYLRPRSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLGMPVATKVI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-KPLYLHSVSDLARFSMP-VQNHS--AFSEFILVGFSNFPPQSLPA----LFLLYLL-MY
LFTLLGNLL-IMATVWSDHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLVGLLSTQH-SITVMACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNELMSSRGCAQLVAWAWAGGSVM----GIMVTSIVFHLTFCGSNEIHH-FVCHVLS
-LLKLACGDETSSVTMGVILVCVTALMGCLFLIVLSYVFIVATILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYGFASIIYLKPKGLH---SIDSST--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KMA---ISK------TFRRKICPQIS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNST--SVAEFLFEGFSSFGWQHRLG----LFVVFLT-LY
LLTLSGNAV-ILTIIRLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPC---MLSGLLSPHQ-TISLQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYM-AICN
PLRYSVIMGKEACIQLATGSLGIGLSM----AIVQVTSVFGLPFCDAFIISH-FFCDVRP
-LLKLACTD-ITINEIINFFVSICVLVVPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLIV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNQDV---KDA---LCR------AMGRKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANLS--AVTEFILIGFSTFPHLQ-LT----FFLLFLL-MY
LFTLLGNLL-IMATIWRERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTHH-SIAFSACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPGGCACLVVWSWAGGLVM----GLVVTSAIFHLTFCGPNEIHH-FACHVPP
-LLKLACGTDVHVVAKGVGLVCLSALLGCCLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCVSHLTV-VVVHYGFASVIYLKPKGPP---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNT---MNK------TFSKLYPETM-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RTNFT--GVREFVFQGFSNYQ-EFHLT----LFVVFFA-LY
LLTLAGNVI-IVTIIRIDQHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLYF-FLGFGI-TNCLLLAVMGYDRYV-AICN
PLRYTIIMNWRVCTILASSVCATGFLL----SLVQAVSIFRLPFCNSL-IEH-FFCDVRP
-MLNLACEV-PVVNDILTLVLTLLVITAPATFLFISYALIISTILKIASADGWKKT----
-----F--------------ATCSSHLTV-VVIHYGCASIVYFKPKSES---TRDQDQ--
-MISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VMGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANLS--AVTEFILIGFSTFPHLQ-LT----FFLLFLL-MY
LFTLLGNLL-IMATIWRERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTHH-SIAFSACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPGGCACLVVWSWAGGLVM----GLVVTSAIFHLTFCGPNMIHH-FFCHMPP
-LVKLACGD-ISIVITGVGLVCLSALLGCCLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCVSHLTV-VIVHYGFASIIYFKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNT---MKK------TFLNKFFLHSC
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------LSRMSLSVG-QPNAT--SWRGFVFLGFSSFG-DLQLL----LFVLFLC-LY
LVTLTSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-VPR---MLSGLVMGDQ-HISYVGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYDSRMHPILCAQLIGISFLNGYLF----GLGMTLVIFHLPFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLVSFLFITISYVFILAAILRIPSAQGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LK-------NVFQRRLL---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-GQNYS--MVTEFILVGFSNFPRHLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTVWSERSLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSTHR-TITWTACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSPRGCARFVSLSWAGGSVM----GMMLTLIVFHLTFCGSNVIHH-FVCHVLS
-LLKLACGNENSSVTLGVILVCVSALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------SS-GQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLVDMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWCWAGGSVM----GMMLTLIIFHLTFCGSNVIHH-FLCHVFA
-LLKLACGKETATVSMAVILLCVTALMGCLFLIFLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGAH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------SFRRTFCPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-DQNYS--TISEFILFGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSVSEILFT--VA--------------
I-TPR---MLADLLSTHH-SITFVSCASQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLHYNVLMSPHDCARLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FACHVLS
-LLKLACGNKTSSVMMGVMLVCVTALIGCLFLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYSFASLIYLKPKGFH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFYRKFCTLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KQNHT--LVSEFTFQGFSNFH-EHQLT----LFVVFLA-LY
ILTLAGNVI-IVTIISLDRHLHT--PMYFFLSMLSASETVYT--LV--------------
I-IPK---MLFNLIGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSIIMNKRVCLQLVWGACSTGLIV----AMIQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTANEILTLIISVLVILIPMSLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VVIHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KEA---LYR------AMGKKLP----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-FILEFFCLFICFLKLRAMRVNQT--LLGEFVFVGFSFYS-DWQVV----LSVFFFF-LY
IFTLTGNLA-IMGLTLLDRGLHT--PMYLFLSALSFSETCYT--LT--------------
I-VPK---MLVDLLTKSR-TISVLGCGLQMFF-FHGLGG-TNCIVLTVMGYDRFL-AICN
PLRYPVLMTNTICGHLVALAWISGFFV----SLVQTTLIFSDSFCGPNLIKH-FLCHMRA
-VVKLSCLN-GAVIEVIVTVISVLGLIGTFLFILLTYVFILSTVLKIPSAEGKRKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPETT-----ERDDI--
-LMAVPYTLI-TPFL----SPLIFTLRNKDM---KYA---LIK------VLSNKSGLTK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVILAENLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFNCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPTLMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACIN-SDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLSV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------RQNQS--VITEFILVGFSNLG-HLQTL----LFFIFLL-VY
LTTLTANAT-IMTVIRLEKALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTVP-TISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIISRATCMQLVLASSVCGFLI----SVVVNILVFSVPFCASNRINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSVEGQCKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDG--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KMA---LRK------VLSRILKFVSC
LKV-K----YP---VDLPPTLKE--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LLFLSHFRHATMKANQT--VLKEFILVGFSSYP-HVRTF----LFVLFFG-LY
LLTLTGNLA-ILGLTWVDRSLHT--PMYLFLRALSFSETCYT--LT--------------
I-IPK---MLADLLTEKR-SISVPGCGLQMYF-FLGLGG-THCIILTLMGYDRFL-AICH
PLRYPLLMTNVVCGQLVVSAWAGGFLI----SVTETALIFGGSFCTPNLIHH-FFCHMRA
-VVRLSCLD-SDLTELVVTMVSVSALTGTFLLIIITYVFILSTVFRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHFGFAAIVYLKPEGS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNRDM---KNA---FRK------LLAKRSFWNT-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-GQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTIWREHSLHT--PMYLFLCALSTSEILFT--VT--------------
I-TPH---MLVNMLSTHH-SISFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWSWAGGSVM----GMMVTMIVFHLTFCGSNEIHH-FFCHVFA
-LLKLTCGKETSSVTLGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VIVHYGFASIIYLKPKGPR---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---MKR------SFHRTFCPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MM-RRNHT--EVSEFVFQGFSSFQ-EYKFT----LFMIFLT-LY
LLTLTGNVI-IVIIISIDRHLHT--PMYFFLCMLSTSETVYT--LV--------------
I-VPR---MLSSLVGSSQ-SMSLASCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNKKVCAQLVLGSCGIGLLV----AIIQIASVFRAPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIINFIISSLVIVVPMGLVFVSYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKKALV---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------TRMGN-HT--RVSTFLLWGFSSFP-DLQNL----LFVVIFF-SH
VTILAANVS-IMVAIKLSHSLHT--PMYFFLFGLSLSETCTT--MV--------------
I-IPR---MLLDLLSESK-TISLPECATQMLF-FFGLSS-NNCFIMAAMSYDRYT-AIHN
PLHYQTLITRKICIQLMMASCIIGFLV----SLCVTITVFNLSFCNANTIDH-FFCDIAP
-VVHLACDY-TPHHEMTIFVLSAFVLVGSFILIMISYIFIVSIIVRMSSTKGRYKA----
-----F--------------STCSSHLTV-VFLHYGFACFVYLKPKNS---DTFYENM--
-LMAVIYTVL-TPLL----NPMVYSLRNKEM---QIA---LRK------VLDNVNRF---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------HSEAK--LHLLFLCALSISEILYT--FA--------------
V-IPR---MLADLLSTDH-SIALRACASQMFF-SFMFGF-THSFLLTIMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVI----GLVVTVAIFQLTFCGSNEIHH-FVCHVQA
-LLKLACGENVSILAMGLGLVCITALLGCCLLILLSYAFIVATILRIPSAEGRHKA----
-----F--------------STCVSHLTV-VIEHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILFGFSAFPHQMLPA----LFLLYLL-MY
LFTLLGNLF-IMAAIWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLSDLLSTHR-SITFIACANQLFF-SFTFGY-THSFLLVVMGYDRYV-AICR
PLHYHVLMSIQGCARLVAWSWAGGSLI----GMTLTIVIFHLTFCDSNVIHH-FLCHVFS
-LLKLACGEGTAFVTIAVILVCVTPLIGCLVFIVLSYIFIVAAILRIPSTEGRHKT----
-----F--------------STCASHLTV-VIVHYGFASLIYLKSRGLH---SLYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------SFYRNICQKSF
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANRS--TVTEFILLGFSAFPR-LQPL----FFPLFLL-MY
LSTLLGNLL-IMATVGLQRGLHT--PMYLFLCTLSLSELLYT--VA--------------
I-IPR---MLADLLAARH-AIALPACACQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYSALMGPRGCACLLGCSWAGGFLM----GLVVTAAIFHLHFCGPNRIHH-FACHVPP
-LLKLACGHGVQPVARAVGLVCIAALLGCCLLILLSYASILGTILRMPSAEGRRKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPRGPP---ALEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KAA---MKK------TFLHKLYPEKR
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANHS--TVTQFILVGFSVFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVGCSWAGGLVM----GMVVTSAIFHLAFCGHKEIHH-FACHVPP
-LLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKSPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFFSKLYPEKN
V---M-M------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KKNST--VVAEFLFEGFSSFDWQHRLG----FFIVFLT-LY
LLTLSGNMI-IVTIIRLDRHLHT--PMYFFLSMLSISETFYT--IA--------------
I-IPR---MLAGLLNPYR-GIDIQCCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGRKACILLASGSLGIGLSM----AIVQVTSVFGLPFCDEFVIAH-FFCDVRP
-LLKLSCTD-TTINEIINFIVSVCVLVVPMGLVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQT---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LRK------AIGLRPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------M-PKSNS--TVTEFLFEGFSSFGWQHRLI----FFAVFLT-LY
LLTLSGNVI-IVTIIHLDRHLHI--PMYFFLSMLSVSETCYT--VA--------------
I-IPR---MLSGLLSPHQ-TIDIRSCASQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKRTCVQLACGSLGIGLGM----AITQVTSVFGLPFCDAFVISH-FFCDIRP
-LLKLACTD-TTVNEIINFIVSVCVLVLPMGLVFISYVLIISTILKITSAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLRQDR--
-LISVTYTVI-TPLL----NPLVYSLRNKEV---KDA---LRR------ALGKKSHST--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MD----N-HT--TGNTFLLWGFSSFP-ELQTL-----LFVVIFSSH
VTILLANVS-IMVAIKLNHNLHT--PMYFFLFGLSFSETCTT--MV--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFF-FFGLGG-NNCFILATMSYDRYI-AIHN
PLQYPMLMTKKICFQLIMASCIIGFLV----SGCIAVIIFTFSFCDSHTIQH-FFCDILP
-VASLACDY-TPFHEMAICMLCAFVLVGSFILIVISYVFILSLVLKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFACYIYLRPKSR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QVA---LWK------VLENGHRFISR
W------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-GQNYS--MVTEFILVGFSNFPRHLLPA----FFLLYLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSTSEILFT--VA--------------
I-TPR---MLVDMLSTHH-TITWAACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSPRGCARLVSWSWAGGSVI----GMMSTLIVFHLTFCGCNVIHH-FLCHVFS
-LLKLACGKETASVTLAVILVCVSALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYSFASIIYLKPKGPH---SMDSNT--
-LMATTYIVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSLLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLR------KKMPS
PLCVLSAQLSFSTG----------------AMSQKKCSTRPVPQKGEEKIIQVSTKATEK
PEQKIRIPIYRQTAPDKQWDNGTW--LVTEFVLVGFSNLP-ELRPT----LFTLFLL-TY
LVTLSGNAT-IITIIQVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-VISIAGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLCLGALVFCSGFSV----ALVETCMIFSSPFCGTGHVEH-FFCDIAP
-VLKLSCAE-STHKGLGIFFLSILVVLVSFLLILLSYAFIVVAILRIPSAAGRHKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPDSGA-N--PSQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRK------NLARGCGVFK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KPNHT--VVTEFILIGFSTFPHLQ-VM----FFVILLL-MY
LFTLLGNLL-IMLTIRSERSLHT--PMYFFLCALSISEIFYT--FV--------------
I-IPR---MLIDLVSSHH-TISFLGCANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMNPQGCAWLVVSSWLGGMVM----GLMVTLSIFHLTFCGPNKIHH-FFCHVPP
-LLKLACGD-TSVVAMGVGMVCITVLLGCFLFILLSYAFIVATILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKAPE---SLEGDT--
-LMGITYTAL-TPFL----SPIIFSLRNKEL---KNA---LKK------VFFSSQYPLRL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------IASTP-GQNYS--TTSEFILCGFSAFPQQLLPS----A---------
-----------------LNRLHT--PMDLFLCALSISEILFT--VS--------------
I-TAR---MLADLLSTHR-SITFVACTNQMFL-SFMFGF-THSFLLMVTGYDCYV-AICH
PLHYHVLMSPRGCARLVAWTWAGGSVM----GMMVTSIVFHVTFCRSNGIHH-LACHVLS
-LLKLACGDKTSSVVMGVMLVHVTALIGCLFLRILSYVFIVAATLRIPS-----------
--------------------------------------------PKGPH---SMYSDT--
-LMATTCTVF-TPFL----SPITFSLRNKEL---KNA---ISE------SFHRISCLSP-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VP-KANST--LVIEFLFEGFSSFGWQHRIV----FFVVFLT-LY
LLTVSGNVI-IVTIIHLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLSDLLSPHQ-CIAIQECATQHFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSIIMGKRSCVHLASGSLGIGLSM----AIIQVTSVFGRPFCDDFVVSH-FFCDVRP
-LLKLACAD-TTVNEIINFVVRVCVLVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVMYTVI-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGGKPLP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-QINAT--CWSGFVFLGFSSFG-ELQLL----LFVLFLS-LY
LITITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFTGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYVSRMNPTLCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCGSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLIAVSYAYILAAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QAA---LR-------NAFRGNLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------KANST--FVTEFLFEGFSSFRWQYRLV----FFVVFLT-LY
LLTLSGNVI-IMTIVRLDHHLHTPHPMYFFLSMLSIFETCYT--VA--------------
I-VPY---MLSGLLNPHQ-PVATHSCATQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRCSVIMSKRACIQLASVSLG--I----------VTSVFGLLFCDAFVISH-FFGDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMDLVFVSYVLIISTILTIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-----L----------------IAP---EEQ---GDA---LRC------SVQSHGAKAPV
SFTKR-------------GCEAFFFEFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RLNLT--AVTEFTFEGFSVLGWQHRLI----LFVVFLV-LY
LLTLASNAI-ILTVIRLNRQLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPC---MLSSLLSPQR-AISIPHCATQLFF-YLAFGI-NNCFLLTAMGYDRYA-AICN
PLRYSVVMGKRTCLQLASGSWSIGLST----AIIQVSSVFSLPFCDANVISH-FFCDIRP
-LMQLACAD-TTIKELVTLLISLCVLVLPMVLIFISYVLIVSTILKIPSARGRKKA----
-----F--------------ATCASHLTV-VVVHYGCASVIYLKPKSHN---SL-KDR--
-LISVTYTVI-TPLL----NPVVYSLRNKDI---KDA---LLR------ALGKNPLS---
-------------------------------

----------------------MEWTNDTMVREFVFLGFSALAGLQ--QLLFMVFLLVYL
FTLGTNAII-MSTIVLDRALHTPMYFFLSVLSCFETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYGRYVAICNPLRYTVLMGHRVCLGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSRLSQLVIFMLGVLVLVIPLLLIL
VSYVRIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFISALQRTMSKTWF-PLN-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TTSTFFLWGFSSFQ-DLQVL----LFVMIFF-FH
VAILTANLS-IMVAIKLSHSLHT--PMYFFLCGLSFSETCNT--LV--------------
I-IPR---MLVDLLSERK-TISLLECATQMFF-FLGLAG-NNCFIMTSMAYDRYT-AIHN
PLHYSMLITRKVCFQLMMTSSVVGFLV----SLCLVIIVFSLSFCDSRTIQH-FFCDIAP
-VISLACDS-TSLHEVLIFVLSAFVLVGSFIFIMISYVFIVFIVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSLHYGFASVVYLRPKKN---DSFYEDM--
-LMAMTYTVL-TPLL----NPIVYTLRNKEM---QLA---LRK------VLGNANRFIHQ
MANKRTMNI----------------------

----------------------MERVNETVVREFIFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYIAICNPLRYSVLMGHGVCMGLVAAACACGFTV
AQIITSLVFHLPFYSSNQLHHFFCDIAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHILSAILQ-FPSTLGRCKAFSTCVSHLIIVTVHYGCASFIYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCKIVRRTISLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VP-KANST---VTEFLFEGFSSFGWQHRIV----FFVVFLT-LY
LLALSGNVI-IVTIIRLDHHLHT--PMYFFLSILSISETCYT--VA--------------
I-IPR---MLSDLLSPHQ-CIATQGCATQLFF-YLTFGI-NDCFLLIVMGYDRYV-AICN
PLRYSIIMSKRSCVYLASGSLGIGLSM----AIVQVTSVFGLPFCDAFIISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLILPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTSIIYLKPKSQS---SLGQDR--
-LISVIYTVI-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGGKLPL---
-------------------------------

------------------------QNNETLVREFVFLGFSSLARLQ--RLLFVVFLLLYL
FTLGTNAII-ISTIMLDRALHTPMYFFLAVLSCSETCYTFIIVPKMLVDLLSQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHGVCVGLVAAACACGFSI
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSHLSQMVIFMLGVFVLVIPLLLIL
VSYIHIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPESNYSSNQDTLI
SVSYTILTPLFNPM-I YSLRNKEVLAENLTIITEFLLLGFSSLGEIQLALFVVFLFLYLI
ILS GNVTIISVIRLDRSLHTPMYFFLGILSTSETFYTFVILPKMLINLLSVARTISFICC
AIQMFFFLGFAITNCLLLGVMGYDRYVAICHPLHYPILMSWQVCGKMAAACGVGGFFASL
TVVNLVFSLPFCSANKVNHYFCDISPVIRLACTNTNAHEFVIFICGVLVLVVPFFFICIS
YFCILRTILRIPSAEGRRKAFSTCASHLTVVVVHYGCASFIYLRPTA NYV---SNK--DR
LVTVSQMDYFELIPWDQVSMANST--SVTEFLLLGFSSLG-HLQLV----LFVIFLS-LY
VIILS GNVT-IISVIFLDRSLHT--PMYFFLCVLSISETFYT--VA--------------
I-LPK---MLINLLSVLR-TLSFMNCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCGQLAVTCIVSGFLI----SMVGTSLVFSLPFCGSNKVNH-YFCDISP
-VIHLACAD-THINELVIFICGVMVLVVPLFFICISYGFIAHTIMRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSARY-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QMA---IRK------VFGKTGFSLKT
V------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------CSN
HCA-FILFLMSPDAASLS-AQNYS--TVSEFILIGFSNFPQHLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
I-TPY---MLVHMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLSYNVLMSTRDCARLVSWCWAGGSAV----GLMVTLIVFHLTFCGSKEIHH-FVCHVLS
-LLKLACGKGTASVTILVILVCVTVLMGCLFLCLIIIFYLFPV-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-RPNFT--VVTEFTFEGFSVFGWHHRLI----FFVVFLV-LY
LLTLASNAV-ILTVIYISHQLHT--PMYFFLGVLSMSETCYT--VA--------------
I-IPR---MLSSLLMPQQ-TISVPGCATQLFF-YLTFGV-NNCFLLAAMGYDRYV-AICS
PLRYSVIMGKRACAHLASGSWTIGLST----AVIQVSSVFSLPFCDANIISH-FFCDIRP
-LMKLACAD-TTIKEFITLLISLCVLVLPMVLIFISYVLIVTTILRMASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------ALGRKPLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-SQNYS--TVSEFILFGFSAFPQQLLPA----FFLLYLL-MY
LFTLLGNLL-IMVTIWTEHRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLSDLLSTRR-SISFVACANQMFF-SFMFGF-THSFLLMIMGYDRYV-AICH
PLHYHVLMSPRDCARLVAWTWAGGSIM----GMMVTSIVFHLSFCGSNVIHH-FLCHVLS
-LLKLACGDTISSVTMGVILVCVTALIGCLFLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYGFASIIYLKPKGFH---STYSDT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KSA---INE------SFHRKFCSVNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNRS--VITEFILVGFSNLG-NLQIL----LFIIFFV-VY
LTTLMVNAT-IMTVIRLDRSLHI--PMYFFLFILSCSETCYT--LV--------------
I-VPK---MLSNLLATNP-SISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRAACMQLVLASSFCGFLI----SVVVNVLVFTVPFCASNRVNH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASSIYLRPTSLH-S--SDKDL--
-LLAVTYTVI-TPLL----NPLVYTLRNKEV---KMA---LRK------VLSRYSFPKTV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-QKNVT--CWRGFVFLGFSSFG-EVQLL----LFALFLS-LY
LITLTSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPK---MLCGLAVGSQ-AISYAGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASFMNPTLCCQLVIASFLSGYLF----GLGMTLVIFCLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TALSELGILILSLVVLLVSFIFITISYTYILANILRIPSAKGRKKA----
-----F--------------STCASHFTV-VIIHYGCASFIYLRPKAS---YSPERDQ--
-LIAVTYTVV-TPLL----NPIVYCLRNQAV---QTA---LK-------NAFQGSLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MPSRPS-------------------LCC----------------------
--S-IPFFCVSSQAPEKLWGNGTW--LVTEFVLVGFSNLP-HLRTT----LFTLFLL-TY
LVTLSGNVT-IITIIHVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPS---MLAHLLMESQ-AISIPACRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSMIMRPTVCLCLGALVFCSGFSV----ASIETCMIFSSPFCRGARVEH-FFCDIAP
-VLKLSCTQ-GARKALGIFFLSVLVVLVSFLLILLSYTFIVATIVKMPSATGRHKA----
-----F--------------STCAAHLTV-VIVHFGCAAIIYLRPDSG---ANPEQDR--
-LVAVFYTVV-TPLL----N--------------------------------PGCTTTPG
FIISL----IAL-V-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDN-HT--AVTTFLLWGFSSFP-ELQGL----LFVIIFF-SH
VTILAANVS-IMVAIKLSHNLHT--PMYFFLCCLSFSETCAA--MV--------------
I-IPR---MLVDLLSDSK-TIFLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHN
PLNYHMLITHSICCQLMMASFVVGFLV----SLCIVITVFNLSFCDSKIIQH-FFCDISP
-VVCLACDY-TFIHEMFIFVLSVFVLVGSFILIMVSYVFIVSIVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFASFVYLKPKNS---GSFGEDM--
-LMAVTYTVL-TPLL----NPIIYSLKNKEM---QLA---LRK------VIGNANKFI--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------TLLKIEIK-IL--LKSRYFGTFYKIPR-S-HTR------SISITMQV
IDFNAANAS-IMVAIKLSQSLHT--PMYFFLCGLSFSETCAT--MV--------------
V-IPR---TLLDLLSVSK-TISLPECATQMFF-FSTLAT-NNCFIMAAMSYDRYT-AIHS
PLHYAIRMTHKICAQLLMASWMIGILV----ALSVVHIVFNLSFCDSNIIQH-FFCDISP
-VMSLACDF-TPYDEMAIFMLSAFVLVGSFILIMISYVFIGSVIMKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFAGFVYLKPKNS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLGNANRFIPQ
KWIKEPKHVNNL-QSI---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNN-HT--TVQTFLLWGFSSFP-ELTNV----LFVVILA-SH
VTILWANVS-IMLTIKLSQNLHT--PMYFLLFSLSLSETCIT--MV--------------
V-IPR---MLVDLLSETK-TISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLHYHTLMTRRICIQLVMASSLAGFLI----SLCITMTIFSLSFCDSNNIQH-FFCDISP
-VVHLACDY-TSYHEMIIFVLSAFVLVGSFILIMISYVFIVAIVVKMSSAKSRSKA----
-----F--------------STCSSHLTV-VCIHYGFASFVYLRPKSS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QIA---LRK------VLENIFNEELN
TTH----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MH-RKNLT--EVTEFVFLGFSRFR-EHQIT----LFVVFLI-LY
TLTLAGNII-IVTIIRIDHHLHT--PMYFFLSTLASSETVYT--LV--------------
I-IPR---MLSSLIAQKQ-PISLAGCTTQMFF-FVTLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMSNRVCVQLMCGAFGIGLAM----AAVQVASIFTLPFCNRV-VGH-FFCDILP
-VMKLSCID-TTINEIINFVVSLFVILVPMGLVFISYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---SVEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGRNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RTNFT--GVREFVFQGFSNYQ-EFHLT----LFVVFFA-LY
LLTLAGNVI-IVTIIRIDQHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLYF-FLGFGI-TNCLLLAVMGYDRYV-AICN
PLRYTIIMNWRVCTILASSVCATGFLL----SLVQAVSIFRLPFCNSL-IEH-FFCDVRP
-MLNLACEV-PVVNDILTLVLTLLVITAPATFLFISYALIISTILKIASADGWKKT----
-----F--------------ATCSSHLTV-VVIHYGCASIVYFKPKSES---TRDQDQ--
-MISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VMGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLCFRFGNQSMK-TENFT--LITDFVFQGFSSFH-EQQIT----LFGVFLA-LY
ILTLAGTTI-IVTIIRIDHHLNT--PMNFFLSMQSTSETVYT--LV--------------
I-LPR---MLSSLVGMNQ-TVSLAG----------------------SMGYDCYV-AICN
PLRYTVIMNKRVRIQLVLGACSIGLIV----AITQVTSVCRLPFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVV-------SL-----------------------
------------------------------------------------------------
-----------------------------EV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--AVSIFILWGFSSFS-DLQSL----LFVVILF-SH
MTILTANVS-IMGAIKLSHNLHT--PMYFFLCGLSFSETCTT--VV--------------
V-MPR---MLVDLLSESK-TISLPECATQMFS-FLGFAS-NNRFIMAAMSYVRYT-AIHS
PLQYHPLMTRKICLQKMMASWMVGFLL----SLCITITVFNLSFCDLNTIRH-YF---SP
-VVSLACNY-TSDYEMAIFVLSACVLMGSFILIMISFVFIVFIVTKMPSAKRRFKA----
-----F--------------SACSSHLTV-VSIHYGFACFVYLRPKNS---NSFHEDM--
-LTAVTYTIL-TPLL----NPIVYGLRNKEM---QIA---LRK------TQGNVIGVF--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCAGQMFF-SFMFGF-THSFLLMAMGYDRYV-AICH
PLRYNVLMSPHDCAHLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FACHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIMAATLRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYSFASLIYLKPKGLH---SMYSDT--
-LMATTYTVF-TPFL----SPIIFSLRNKKL---KNA---INK------NFHRKFCLLSS
C---VPIWW----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
RF-LNR--SYFFLTSLQVVAENFT--AIGEFLLLGFSSLG-DIQLA----LFVVFLF-LY
LVILSGNAT-IISVIRLDQSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACGIGGFLA----SLTVVNLVFSLPFCSANRVNH-YFCDISP
-VIRLACTN-TDVHEFVIFVCGVLVLVVPFFLICVSYLCILRTIVRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTADY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------ALGKKWSLKP-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-SKNHT--VVSEFILQGFSSFQ-EHKII----LFVIFLP-LY
LLTLAGNVL-IVTVISLTRHLHT--PMYFFLSVLSISETVYTLTLV--------------
I-VPR---MLCSLTGLNQ-PISLAGCATQMFF-FLTLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVLMNKRVCALLAWGALSIGLLV----AVVQISSVFRLPFCDRE-VAH-YFCDILP
-VMKLSCAD-TTLHDIINFIISSFVIVVPMGLVFISYVLIISTILKISSAQGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LRR------AISKNPLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VAAML-GVNHT--FMPQFILIGFSAFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSERSLHT--PMYLFLCALSISEILYT--FV--------------
I-IPR---MLADLLSTHH-SITFVACGNQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPHGCACLVAWSWIGGSVM----GMVVTTAVFQLTFCGPNEIRH-FFCHVPP
-LLKLACGENVPVVAKCVGLVCITVLLGCCLLILLSYAFIVSTILRIPSAEGQHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFLSKLSLQNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------SQAPEKQRGNGTW--LVTEFVLVGFSNLP-HLRTT----LFTLFLL-TY
LVTLSGNVT-IITIIHVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISISGCRAQMFF-FLGLGC-NNCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLCLGALVFCSGFSV----ALAETCMIFSSPFCRGGRVEH-FFCDIAP
-VLQLSCAD-SAHRALGIFFLSVLVVLFSFLLILLSYAFIVAAILRIRSAAGRRRA----
-----F--------------STCAAHLTV-VVVHFGCASIIYLRPDSGA-N--PARDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LKR------TLARSGGLSR-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MAAVLGSKVVLAENFT--MVTEFLLLGFSSLG-KIQLT----LFVVFLF-LY
LVILSGNVT-IISVIHLDQSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFVCCAIQMFF-FLAFAI-TNCLLFGVMGYDRYA-AICH
PLHYPILMNWQVCGKLAAACGIGGFLG----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLVLVVPFFFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPSANY-V--SNKDR--
-LVAVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRR------VLGKKGSLLHD
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQGFNRTT--VVTQFILVGFSSLG-ELQLL----LFVIFLL-LY
LTILAANAT-IMAVIHFSRVLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSATK-TISFMACASQLFF-FLCFAC-TNCFLIAAMGYDCYV-AICH
PLRYTLIMDKRLGLGLVSLSGVTGFLI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-TQVKELALFSLSILVITVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQDV---KAA---LKR------FLRMPVA----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TENYT--GVREFIFQGFTSFH-EHKLT----LFVVFLT-LY
LLTLSGNVI-IVTIISIDRHLHT--PMYFFLTALSTSETLYT--LV--------------
I-VPR---MLSSLVGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYMIIMNKRVCAQLVWGACSIGLFV----ATIQISSVFRLPFCYRK-VAH-YFCDIRP
-VMKLSCAN-TTIHDIINFLISSLVIVVPMVLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---MRDQDQ--
-LISVTYTVS-TPLL----NPVVYTLRNKEV---KDA---LCR------AIGKNLLLRIF
GSLIY-------------SLS-YSG------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MENLIFICCFFPISGIQRMKINHT--ILKEFILVGFSVYP-HAQTL----LFVVFFC-LY
LLTLTGNLA-IMYLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-TPK---MLSDLLTKNR-GISVIGCGLQMYF-FLGLGG-THSIILTLMGFDRFL-AICN
PLRYPLLMTNVVCGQLVASAWVAGFII----SITETALIFRGSFCGPNLVKH-FFCHMRA
-VVRLSCLD-SELTELIVTAISVSALMGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VFIHFGFASIVYLKPGAS-----GGDDT--
-VIAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGKTSSLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSLG-KHQIT----IFGVFLT-VY
VLTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEKVYT--LV--------------
I-VPR---MLCSLIFHNQ-PISLAGCASQMFF-FVILAI-NNSFLLTAMGYDRYV-AICR
PLRYTVIMSKGLCAQLVCGSFGIGLEE----DLCHLCL---PPHCGHC-PLW-LFLHCLP
-QAQ------------------------------------------------VRKL----
-----Y--------------RTR---------------------P---------------
----PSVSVL-HHHH----SPAVYSLRNKEV---KNA---LRR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-QDNVT--CWKGFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFLGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTLCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QSA---LR-------NAFRGSLLRKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-KPNST--FVTEILFEGFSSFRWQHRLA----FFVVFLT-LY
LLTLSGNVI-IVMIIRLYHHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLSGLLNPYQ-PITIQGCATQLFF-YLTFGI-NNCFLLIVMGYDRYV-AICN
PLRYSVIMGKRACVQLASGSLGIGLDM----AIVQVTSVFGLPFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCALVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLIV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYT----------------P---EEQ---G-S---QRC------SAQGRGAKAPV
SLMRK-------------GCKGFFFEFINV-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RPNYT--VVNEFTFEGFSSFRWQNRLI----LFVVFLG-LY
LMTLTGNGI-IVTIIRLDRHLHI--PMYFFLSVLSISETCYT--LA--------------
I-IPR---MLADLLSPQQ-PIAIPECATQLFF-YLTFGI-NNCFVLTAMGYDRYV-AICN
PLRYSIIMRKSVCAQLACGSWGIGLGM----AIIQVTSVFGLPFCDATVISH-FFCDVRP
-LLKLACVD-TTINEIINFVVSVCVLVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLEQDR--
-LISVTYTVI-TPLL----NPVEQGSQGCST---PSS---RQENLVFLVTRNRKGFSFRF
LLYF---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GPNHT--IVSEFILVGFSTFPQLW-LI----LFVVFLL-MY
LFTLLGNLL-IMLTIQSERNLHT--PMYFLLCALSISEIFYT--FA--------------
I-IPR---MLTDLVSKYH-TISFMGCANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMNSQGCALLVASSWFGGMVM----GLVVTLAVFHLTFCGPNKIHH-FFCHVPP
-LVKLACGD-ISIVAMGVGMVCITALLSCFLLILLSYAFIVATILRIPSTEGRHKA----
-----F--------------STCVSHLIV-VVVHYGFASVIYLKPKAPE---SLEGDT--
-LMGITYTAL-TPFL----SPIIFSLRNKEL---KNA---LKK------VFFS-------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENLTVACLSEFVFQGFSSFH-EHRFI----LFVAFLT-LY
LLTLAGNVV-IVIIISIDRYLHT--PMYFFLGMLSTSETVYT--LV--------------
I-VPR---MLSSLVGLSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKKVCAQLVWGACSIGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTVHDIINFIISSVVIVVPMGLVFISYILIISTILKIASSEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTIF-TPLL----NPVVYTLRNKEV---KDA---LYR------AIAKKRLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MILFANVS-IVMAINLNHNLHT--PMYFFLFGLSFSETCTT--MV--------------
I-IPR---MLADLISNSK-TISLPECATQMFL-FFGLGA-NNCFILAAMSYDRYT-AIHN
PLHYPMLITRNVCFQLMMASAVVGFLV----SLCIVIIVFNLSFCDSNSIRH-FFCDIAP
-VASLACNY-AFFQKMVLLAFTAFVLVGSFILIMISYVFIVSLVVKMPSAKGRRKA----
-----F--------------STCSSHFTV-VSVHYGFACFVYLRPKNSD-TDSFGENT--
-LMAVTYTVL-TPLL----NPIVYI-----------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTMFLLWGFSSFP-ELHNL----LFLVVLF-SH
VTIILANAF-IMVAIKLNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---LLVDLISKNK-AISLPECATQMFF-FFGLGG-NNCFILSAMSYDRYT-AIHN
PLHYPILMTQKICLHLIVASGVLGFLI----SLCIVITIFNLSFCNSNIIQH-FFCDIDP
-VVSLACNL-TFYHKVILFALTAFVLVGSFIFIMVSYVFIVTVVIKMPSAKGRYKT----
-----F--------------STCSSHFTV-VFIHYGFASFVYLRPKNS---YSFRDAT--
-LLAVTYTIL-TPLL----NPIIYSLRNKGI---QTA---LRK------DIGNIIRFFSK
KV-NKKAQKI---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------VNSRNQVNQANVS--SVTEFLLLGFSSLG-ENQLI----LFAVFLC-LY
LIILSGNIT-IVTVIHLDCNLHI--PMYFFLGILSISETCYT--FV--------------
V-LPK---MLINLLSVLR-TISFISCATQTFF-FLGFAV-TNCMLLGVMGYDRYA-AICH
PLRYPILMSWQICGQLAASCAGIGFLF----SLVGTLLVFRLPFCGPSKVNH-YFCDISP
-VIRLACTD-SNINELIIFIGGVLALMVPMTFICISYGFIVCTILKIPSAEGKLKA----
-----F--------------STCASHLTV-VIIHYGCASFVYLRPSSKF-S--SSKDR--
-LVTVTYTVF-TPLL----NPMVYSLRNKDV---QMA---IQK------VLGRGKC----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MHLLPFCFQVLAENLT--MVTEFLLLGFSSLG-DIQLV----LFAVFLF-LY
LAILSGNVT-IVSVIRLDKSLHT--PMYFFLGILSTSETCYT--FV--------------
I-LPK---MLINLFSVAR-TISFNCCAIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWQVCGKLGALCGIGGFLA----SLTVVYLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDAHEFVIFICGVLVLVVPFLFICVSYIYILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASYIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QVA-----------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------TMQINQT--RVKEFILIGFSLYP-DVQIL----LFVIFFC-LY
FLTILGNLT-IMGLTWVDRALHT--PMYIFLSSLSFSETCYT--LG--------------
I-IPK---MLADLLAKNR-TISVIGCGLQMYF-FLGLGG-TNCIILTVMGYDRFL-AICN
RLRYPLLMTHILCGELVASAWAGGFFV----SLIETALIFRDFFCSPNLVKH-FFCHMRA
-VVRLSCLD-SNLTEFMVTLISVLGLLGTFLFITLTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCVSHLTV-VIIHFGFASIVYLKPEGS-----WGDDT--
-LIAVPYTVI-TPFL----GPLIFSLRNKDM---KNA---FRK------VVGKI------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--VVTEFILIGFSNLG-NLQSL----LFFIFLL-VY
LTTLMANLT-IMTVIRLDRTLHT--PMYFFLFILSCSETCYT--LV--------------
I-VPK---MLANLLSTYP-SISFSGCAAQMYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYMIIV------------SFCGFLI----SMVVNILVFSLPFCASNQINH-YFCDIFP
-VLKLGCTD-TNLKEMTIFLLSILVLLVPFVLIFISYVFIVSTILKISSLEGQCKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTALY-S--SDKDL--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LRR------IVSRYSFSK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MVGSFGSRHGLKGKT-KPAA----------VQSPELGWPHRLV----F-AVFLS-LH
LLTLSSNIIIIVTVVRLNHHLHT--PMYFFLSMLSLSETCYT--VA--------------
I-IYASCPFLSSLLSPQR-AISIPDCATQLFF-YLTFGI-NNCFLLTATGYDCYV-TTCN
PLWYSVIMSKEACVQLASGSLGTGLGV----ATVQVTSVFGLPFCDALVIFH-FFCDVRP
-LLKLACVD-TPVNEIINFVVSVCVLILPTGLVFFSCVLIVSASLKIPPARGWKKA----
-----F--------------ATCTSRLRV-VIVHYGCASVAYLKPKSRS---SLGQDR--
-LISVTYTVL-TPLL----SPVVYSLRNKEV---KDA---LRR---------GVGQKPLS
S------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFI-LGFSSLG-KHQIT----ISGVFLT-VC
ILTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEMVYT--LV--------------
I-VPR---LLCSLIFHNQ-RISLAGCATQMFF-FVILAI-NNCFLLTAMGYDCYV-AVCR
PLRYTVIISKGLCAQLVFGSFGI-------------------------------------
------------------------------GLIFTSYVLIISFFLKIASTEGWKKT----
-----F--------------ATCASHLTV-VIVHRGCSSTTYLKPKSEN---STEQDL--
-LLSVTYTII-APLL----NPVVYRLRNKEV---KDA---LCR------VVGRYIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------SSSRYAAML-GLNYT--SVSEFILIGFSTFPQHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLLLCALSISEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFTACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLHYNVLMSPRGCACLVAWSWAGGSVM----GLLVTSAVFHLPFCGLSEVHH-FFCHVPP
-LMKLACGNNVLGVALGVGLVCSMVLLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYSFASVIYVKLTGLH---SQQGNI--
-LIAITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------TFLSKLSFQRL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EMAEFIFLGFSIFG-KHQIT----LFVVFLT-MY
ILVLAGNIT-IVTVICIDHRLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSGLIFHNQ-PISLAGCATQMFF-FVVLAT-NNCFLLTVMGYDRYV-AICK
PLRYTVIMNKGMCAGLVCGSFGTGLVM----AVLHVTAMFRLPFCGSM-VDH-FFCDIYP
-VMKLSCID-TTVNEIINYGVSSFVIFVPVGLIFISYIFVISSILKIPSAKGRKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---AIEKDL--
-LLSVTYTIV-TPLL----NPVVYSLRNKEV---KDA---LRR------AVSRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MVANVHCCFFQISSTPTMQINKT--ILKEFILVGFSVYP-DIQAF----IFVVFLC-LY
LFTFMGNMT-IMGLTWVDTALHT--PMYLFLSALSFSETCYT--MS--------------
I-IPK---MLADLLAKNR-SISIVGCGLQMCF-FLGLGG-TNCLILTAMGYDRFL-AICN
PLRYPLLMTNIVCGKLVASAWAEGFFI----SVIQTALIFKGVFCNPNLVKH-FFCHMQA
-VVKLSCLD-SDFTEFIVTVISVSGLLGTFLLISLTYIFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFPSIVYLKPEAS-----WGDDT--
-LIAIPYTVI-TPFL----SPLIFTLRNKEM---KNA---FRK------VLGKTVALDK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--SVSEFILIGFSTFPQHLLPV----FFLLFLL-MY
LFTLLGNLL-IMATVWNERGLHT--PMYLFLCALSTSEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFTPGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVVWSWAGGLFI----GLLVTSAIFHLPFCGLNEVHH-FLCHVPP
-LLKLACGNNVPGVALGVGVVCITALLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYSFASVIYLKPKGLY---SEEGNT--
-LMAITYTVL-TPVL----SPIIFSLRNKEL---KIG---IKK------TFLSKLYPSSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NLT--MVTEFLLLGFSSLG-EIQLA----LFVIFLF-LY
LAILSGNVT-IISVIRQDQSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPR---MLINLLSVAR-TISFICCAIQMFF-FLGFAM-NNCLVLGVMGYDRYA-AICH
PLHYPILMSWQMCGKLAAACGIGGFSA----SLILVNLVFSLPFCGANKVNH-YFCDISP
-VIHLACTN-TDVYEFAVFICGVLAIVVPFLFICVSYVCILKTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASYIYLRPTANY-V--SSKDR--
-LVTVMYTIV-TPLL----SPMVYSLRNKDV---HIA---LRK------V----------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MW-GANGS--AVTEFILIGFSTFLHLQ-LM----FFLLFLL-MY
LFTLLGNLV-IMATVWSKRGLHT--PMYLFLCALSISEILYT--VA--------------
I-IPR---MLANLLSTQR-SITLLACASQMFF-SFTFGF-THFFLLTVMGYDRYV-AICH
PLRYNVLMSPQGCACLVGWAWAGGSVM----GLVVTVAIFQLTFCGPNEIHH-FACHVPP
-LLKLACGDDVPVVAKGVGLVCITALLGCCLLILLSYALIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KSA---MKK------TFLSKLCPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
TLFISLPSSCRPRPSSMP-KPNST--AVTEFLFEGFSSFGWQHRLV----FFVVFLT-LY
LLTLSGNAI-IVSIICMDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPQ---MLSGLLSPHQ-PIAVQGCATQLFF-YLTFGI-NNCFLLVAMGYDRYV-AICN
PLRYSVIMGKEACVRFVSGSLGIGLGM----ATVQVTSVFCLPFCDAFVISH-FFCDVRP
-LLKLACID-TTANEIINFVVSICVLVLPMSLVFVSYVLIISTILKISSAEGRKKA----
-----F--------------ATCASHLTV-VVIHYGCASIVYLKPKSQS---SIGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LCR------AMGRKPRS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-RLNFT--AVTQFTFESFSSFEWHHRLI----LFVVFLV-LY
LLTLASNAI-ILTVIRLNRQLHT--PMYFFLGMLSISETCYT--MA--------------
I-IPQ---MLSSLLRPQQ-AISIPGCATQLFF-YLTFGV-NNCFLLTAMGYDRYV-AICN
PLRYSLIMGKKACLQLASGSWIIGLST----AIIQVSSVFTLPFCDASVISH-FFCDVRP
-LMKLACAD-TTSKEFITLLISLCVLVLPMILIFISYVLIVTTILRMASAEGWKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-IPLL----NPVVYSLRNKEV---KDG---LLR------VLGRKPLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VP-GTNST--FVTEFLFAGFSSFGWQHRLV----FFVVFLT-LY
LLTLSGNVI-IVTIIHLDHHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLSGLLNPRQ-TISFQDCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSAIMGKGACIQLASGSLGIGLSM----AIIQVTSVFGLPFCDDFVISH-FFCDVRP
-LLKLASTN-TTVNEIINFVVSVFVLVLPMALVFISYVLIIATILKIATADGRKKA----
-----F--------------ATCASHLMV-VIIHYGCASIIYLKPKSQS---SLVQDR--
-LISVTYTVI-IPLL----NPVVYSLVKDAL---GRG---KP-------------IST--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--TITEFILIGFSNLG-DLQIL----LFFIFLL-VC
LTTLMANTT-IMTVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPS---MLTNLLSTSP-TISVPTCAAQLYF-FVGLAC-TNCFLIAVMGYDRCA-AICN
PLNYTLIV------------NFCGFLV----SAVVNVLVFSVPFCASNQINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSVEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAETYTVI-APLL----NPLVYTLRNKEV---KTA---LRR------LGRDS-PP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANRS--AVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTHR-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVGWSWAGGAVM----GMVVTTAIFHLTFCGPNKIHH-FACHVPP
-LLKLACGDDVPVVAKGVGLVCITALLGCCILILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SMEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---IKK------TFFNKLSPKNV
----T-IW-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDN-HT--TVSTFLLWGFSSFP-DLQGL----LFVMIFF-SH
VTILAANVC-IMVAIKLSHNLHT--PMYFFLCGLSFSETCTT--MA--------------
I-IPR---MLVDLLSDSK-AISLPECATQMFF-FFGLGA-NNCFIMAAMSYDRYT-AIHS
PLHYKVLMTHKICFQFMMASWMAGFLV----SLCIVITVFNLSFCDSNIIEH-YFCDISP
-VVCLACDY-TSHHEMAIFVLSAFVLVGSFVFIMMSYVFIVSRVVKMPSTKGKYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKDM---QTA---LRK------VLGKTNRFIPQ
MGSRRTPDIKN------------VQTVDK--

----------------------MEQGNETLVREFIFLGFSSLAGLQ--RLLFVAFLPLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFV
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTELMGHRVCVGLVATACACGLTI
AQIITSLVFYLPFRSSNQLHHYFCDIPPVLKVASQHTHLSQIVIIMLCALVLVIPLLLIL
VSYIHIISAIIQ-FPSTLGRYKAFSTCASHLIVVTIHYGCASFIYLRLKSTYSSSQDALI
SVSYTMLTPLFNPL-IYSLRNKEFRSALHRAVRKIIFLPQC-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------AAINN---------LLFW-----V--YG--------------
--CP----EESNNIVQSQ-AISYVGCAVQMDF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMHPTLCTQLVGTSFLSGYLI----GMGMTLVIFQLPFCGSHEIHH-FFCDTPP
-VLSLACGD-TSMSELEILILSLLVLLVSFSLITISYANILVTILRIPSAKGKQKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL---------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPQILI
FT-YLN--IFYFFPSLQILAENVT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LAILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGLMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-IIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPVVYSLRNKDV---QLA---IRK------VLGKKGSLKL-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MTNQT--ILKEFILVGFSAYP-LSQTC----LFVVFLC-LY
MVTLAGNLT-IMGLTWVDRSLHT--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLIDKDS-RISVTGCGLQMCF-FLGLGG-TNCILLTVMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFVVTLMSVSGLLGTFLLILLTYMFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VLIHFGFASVVYMKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDM---KNA---FRK------IMRKTVVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QVNVT--CWRGFVFLGFTSFG-ELQLL----LFALFLC-LY
LVTLTSNVF-IIVIIRLDSPLHM--PMYLFLSFLSFSESCYT--LG--------------
I-IPR---MLSGLALGVQ-TISYMGCAAQMFF-SGSWAC-ANCFLLSVMGFDRYV-AICT
PLHYASRLNPTLCSQLVGIS-LSGYLF----GLGMTLVIFCLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLVSFFIITISYAYILAAILRISSAEGRKKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLEWDQ--
-LIAVTYTVV-IPVL----NSIIYKTAENNA---VDG---VDP------NADR---LGC-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MR-RANAT--TWKGFVFLGFSGFG-ELQLL----LFALFLC-LY
LVTLASNVF-IIVVIRLDSHLHT--PMYLLLSFLSFSEICYT--LG--------------
I-VPR---MLSSLVMVGQ-AISYEGCAAQMFF-SASWAC-TNCFLLAVMGFVRYV-AICA
PLHYATRMNPASCAQLVGAFFLSGYLF----GLGMTLVIFHLPFCGSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLVSFSSITVSYAYILTAILRIPSAQGRKKA----
-----F--------------STCASHLTV-VVAHYGCASFMYLRPKAS---FSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------SAFRGTLLQR-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GVNHS--RVTEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTHR-SIAFLACANQMFF-SFTFGF-THSFLLTIMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSVM----GVVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGKEVLVVAKGVGLVCIMALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------ACLSRLYPE--
----------KI-------------------

----------------------MEWINETVVREFVFLGFSSLAGLQ--RLLFAVFLFLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHGACTGLVAAACVCGFTV
AQIITLLVFHLPFHSSNELHHFFCDISPVLQVASHHTHFSQIVIFMLCSLVLVIPLLLIL
VSYIHIISAILQ-FPSKLGR----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENLT--VVNEFVFQGFSSFR-EHKLI----LFVFFLI-LY
LLTLASNAI-IVIIISIDRYLHT--PMYFFLSMLSTSETLYT--LV--------------
I-VPQ---MLSSLVGLSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYLVIMNKKICAQLVWGACSIGMFV----AIIQISSVFRQPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTVHDIINFIISSMVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCGSHLTV-VIVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTIF-TPLL----NPVVYTLRNKDV---KDA---LYR------AIGKKRLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MLMP-QPNST--SVTKFLFEGFSSFGWQQRLV----FFVVFLL-LY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSILSISDTCYT--VV--------------
I-IPH---MLYGLLNLQK-TISFQDCVTQLFF-YLTFGI-NNCFLLMAMGYDRYV-AICN
PLRYSVIMGKRACVQLALGSLGVGLSM----AIVQVTSVFSLPFCHDFVIPH-FFCDVRP
-LLKLACAN-TTLSEIINFVVSVFVLILPMCVVFISYILIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VTIHYGCTSIIYLKPKSQN---LLGQDR--
-LISVTYTVI-TPLL----NPLVYSLRNKEV---KDA---LYK------ALGRKPIST--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ME-HTNAT--SWRGFVFLGFSSFG-ELQLL----LFVLFLF-LY
LITLMSNVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSSLVMGIK-AISYVGCAAQMFF-SASWAC-ANCFLLAVMGFDRYV-AICA
PLHYASHMNPTLCVQLLGTSFLSGYIF----GLGMTLVIFHLPFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLVSFSFITVSYTYIVAAILRIPSAEGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAT---YSLERDQ--
-LIAVTYTVV-TPLL----NPVVYSLRNRAV---QKA---LR------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-ESNVT--CWRGFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTVCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGSLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--SWRDFVFLGFSSSG-ELQLL----LFALFLS-LY
LVTLTSNVF-IIIAIRLDSHLHT--PMYLFLSFLSLSETCYT--LG--------------
I-IPR---MLSGLAMGDH-TISYVGCAAQMFF-SASWAC-TNCFLLAAMGFDRYV-AICA
PLHYASRMNPTLCAHLVVTSFLIGYLF----GLGMTLVIFHLSFCSSHEIQH-FFCDMPP
-VLSLACGD-TGPSELRIIILSLLVLLVSFFFITISYAYILAAILRIPSAEGQKKA----
-----F--------------STCASHLTV-VIIHYSCASFMYLRPKAS---YSLERDQ--
-LIAMTYTVV-TPLL----NPIVYSLRNTAV---QTA---LR-------NAFRGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNIT--SWGGFVFLGFSSFG-ELQLL----LFAIFLS-LY
LITLASNVF-IIVVIRLDSQLHT--PMYLFLSYLSFSETCYT--LG--------------
I-IPR---MLFGLALGDQ-AISYVGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMHPTFCAQLVGTSFLSGYFF----GLGMTLVIFHLRFCSSHEIQH-FFCDTPP
-VLSLACGD-AGLSELGILILSLLVLLVSFSLITISYSYILAAVLKIPSAKGQKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YCLERDQ--
-LIAVTYTVV-TPLL----SPIVYSLRNRAV---KAA---LK-------NAFQR-LVGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MRVPPRMG-QTNAT--AWRGFVFLGFSGFG-ELQLL----LFALFFS-LY
LVTLTSNVF-IIVVIRLDSHLHT--PMYLLLSFLSFSETCYT--LG--------------
I-IPK---MLSSLVMGGQ-AISYEGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMDPPFCARLVGTSFLSGYLF----GLGMTLVIFHLPFCGSHEIQH-FFCDTPP
-VLSLACGD-TGPSELGILILSLLVLLVSFSFITISYAYILAAILRIPSTEGRKKA----
-----F--------------STCASHLTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------SAFQGRLLGAG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-NQNYS--MMSEFILIGFSNFPQQLLPI----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
I-TPY---MLVHMLSTHH-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWCWAGGSVM----GMMVTLIVFHLSFCGSNEIHH-FFCHVLS
-LLKLACGKGTASVTMVVIMVCVTALMGCLFLIILSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASLIYLKPKGAH---SMDSNT--
-LLATTYTIF-TPFL----SPIIFSLRNKEL---KNA---IKR------TFCRTFCPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MLNYT--SVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWREHSLHT--PMYLFLCALSISEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFTPGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVVWSWAGGLVV----GLVVTSSIFQLTFCGSNEIHY-FGCHVPP
-LLKLACGTEVQIVAMGVGLVCIAALLGCGLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKLYPSSV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--FVTEFLLLGFSSLG-ELQLV----LFVVFLS-LY
LIILSGNLT-IISAIHLDSSLHT--VMYFSLGVLSTSEIFYA--IV--------------
I-LPK---MLINLLSVLR-TLPFMRCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-ALCQ
ALHYPILMSWRVCGQLAATCIVSGFLI----SLVGTALVFSFPFYGSNKVSH-YFCDISS
-VIHLACAE-TYINELVIFICGVLVLVVPLIFICTSYGFIVRTIMKIPSVEGKQKA----
-----F--------------STCVSHLIV-VIVHYGCASFVYL-----------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MENLIFLCCFYWILGVQTMKINQT--ILKEFILVGFSVYP-HVQTF----LFVVFFG-LY
LLTLTGNLA-IMGLTWVDRSLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPR---MLTDLLAKNR-SISVTGCGLQMSF-FLALGA-TNCFLLTVMGYDRFL-AICN
PLRYPLLMTNMVCGQLVASAWAAGFLV----SVIETALIFRGSFCSPNLVKH-FFCHMRA
-VVRLSCLD-SDLTEFIVMAISVSGLMGTFLLIILTFVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHFGFASIVYLKPEAS-----GGDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNKDM---KGA---FRK------VLGKTILLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNAT--SWKGFVFTGFSRFG-ELQPL----LFALFLS-LY
LVTLTSNVF-IIVLIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSSLVRGGQ-DISFVGCAVQMFF-SASWAC-TNCFLLAVMGFDRYV-AICT
PLRYASRMVPTLCAQLVGTSFLSGYLF----GLGMTLVIFHLPFCSSHEIQH-FFCDT--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANHT--ELREFVFQGFSNFP-EHHV---------------
-------L--------------------------STSETFYS--LV--------------
I-IPR---MLSSLVSPSQ-SISLEGCGTQIFF-FLGFAI-TNCLLLAVMEYDHYVVAVCN
PLRYPVIMNWRVCAILASSVCATGFSL----SLVQSVAIFRLLFCTPL-IEH-FFCDIQP
-VLDLAWAT-PMINDILTLIMSLLAITAPATFLFISYVLIISTILKITSAEGGKKT----
-----F--------------ATYASHLTV-VIIHYGCASIAYFKPNLKN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYGLRNKEV---QDA---LQR------VLGRKFFS---
-------------------------------

----------------------MERGNETLVREFTFLGFSSLAGLQ--RLLFIAFLPLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTELMGHRVCVGLVAVACACGFTI
AQIITSLVFHLPFHSSNQLHHYFCDISPVLQVASHHSRLSQLVIFMIGVFVLVIPLLLIL
VSYIRIISAILK-IPSSTGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSSYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRVMGQTSYPIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KQNYT--LVSEFIFQGFSNFH-EHQLT----LFVVFLA-LY
ILTLAGNVI-IVTIISLDRHLHT--PMYFFLSMLSASETVYT--LV--------------
I-IPR---MLFNLIGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRFV-AICN
PLRYSVIMNKRVCLQLVWGACSIGLIV----AVIQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTANEILTLIISVLVILIPMSLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VVIHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LYR------AMGKKLP----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVILAENLT--MVTEFLLLGFSSLD-EIQLA----LFVVFVF-LY
LVILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMRWQVCGKLAAACAIGGFLV----SLTVVNLVFSLPFCGANKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSGEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------LLGKKGSLKPY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--FWRGFVFLGFSSFG-EFHLL----LFAVFLS-LY
VITLTSNVC-VIIVIRLDSHLHT--PMYLFLSYLSFSEACYT--LG--------------
I-IPR---MLSGLIVGDQ-AISYAGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLNYASRMHPTFCAQLVGTSFLTGYFF----GLGMTLVIFHLQFCSSHEIQH-FFCDTPP
-VLSLACGN-TGLSELGVFVLSLLVLLVSFFFITVSYAYILAAILKIPSAQGRKKA----
-----F--------------STCASHLTV-VIIHYGCASFMYLRPKSS---YSLERDQ--
-LIAVTYTVV-TPLL----NPLVYSLRNRAV---KTA---LK-------NVFQGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLR------KKMPS
PLCVLSAQLSFSTG----------------AMSQKKCSTWPVPQKGEEKIMQVSTKATEK
PEQKTKAPRHRQTAPDKQWDNGTW--LVTEFVLVGFSNLP-ELRPT----LFTLFLL-TY
LVTLSGNAT-IITIIQVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISISGCRAQMFF-FLLLGC-NNCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLYMGILIFCSGFSV----ALVETCMIFSSPFCGTGRVEH-FFCDIAP
-VLKLSCAE-STHKGLGIFFLSILVVLVSFLLILLSYAFIVVAILRIPSAAGRHKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPDSGA-N--PSQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRK------NLAQAAGSACF
NKT-RLS------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRGFNKTT--VVTQFILVGFSSLG-ELQLL----LFVIFFL-LY
LTILLANVT-IMTVIRLHRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSETK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLVSLSGVTGFFI----ALVATNLICDMPFCGPNRINH-YFCDMAP
-VIKLACTD-THVKELVLFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDE--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLGMPGENKMS
-------------------------------

----------------------MERVNETVVREFIFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVTVPKMLIDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYIAICNPLRYSVLMGHGACMGLVAAACACGFTV
AQIITSLVFHLPFYSSNQLHHFFCDIAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHILSAILQ-FPSTLGRCKAFSTCVSHLIIVTVHYGCASFVYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCKIVRRTIFLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENLT--VVSEFIFQAFSSFH-EHRLI----LFVVFLT-LY
LLTLAGNAV-IVIIISTDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLACLIGPSQ-SISLAGCATQMFL-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTAIMNKKVCSQLVWGACSCGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTVHDIINFIISSMVIVVPMGLVFISYILIISTILKIASAAGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKSKSEN---TRDEDQ--
-LISVTYTIF-TPLL----NPVVYTLRNKEV---KDA---LYR------AIAKKSLA---
-------------------------------

------------------IAVTMEWANETLVTEFVFLGFSSLAGLQ--RLLFVVFLLVYL
FMLGTNVII-VSTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFFFLFLICSHSFLLAAMGYDRYVAICNPLRYTVLMGFGVCVGLVAAACACGFII
SLATTSMIFHLPFHSSNQLHHFFCDVSPVLKLASHQSYLNQLVIFVLGVFVLVIPLLLIL
VSYVLIISAIVK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRAMTHTSYSIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------F
ASPY----ISMMRVRRMQ-RKNFT--EVTEFIFLGFSVFG-KHQIT----LFVVFLT-IY
IITLTGNVV-IVTIIRVDHHLHT--PMYFFLSMLASSETVYT--LV--------------
S-VPR---MLSGLLFHNQ-PISLAGCASQMFF-FVLLAT-NNCFLLTAMGYDRYV-AICN
PLRYTVLMSKAVCVMLVSGSFGTGLVM----AVLHVAAMFSLPFCGTV-VEH-FFCDIYP
-VMKLSCID-TTVNEMINYGVSSFVILIPVSLIFISYVFIISTILKIASTEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKSKSED---SAEQDV--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KGR---LSS------SGVKPLAL---
-------------------------------

----------------------MERGNGTLVTEFVFLGFSSLAGLQ--RLLFVAFLPLYL
FTLGTNAII-VSTIVLDRALHTPMYFFLAVLSCSETCYTFVIIPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGHRVCVGLVAAACACGFTI
AQIITSVVFHLPFCASNQLHHFFCDIAPVLTVASHHTYLSQIVIVMLCALVLVIPLSLIL
VSYIHIISAILQ-FPSTLGRYKAFSTCASHLIVVTIHYGCASFIYLRLKSNYSSSRDALI
SVSYTILTPLFNPL-IYSLRNKEFKSALRRAAGKTISLPRC-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

----------------------MECVNETLVSEFVFLGFSSLAGLQ--RLLFAAFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLTVLSCFETCYTFVIIPKMLIDLLAQKKTISFL
GCAMQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTVLMGHGVCGGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLKVASYHTHFSQIVIIMLCALVLIIPLLLIL
VSYIRIISAILQ-FPSTVGRYKAFSTCASHLIIVIVHYGCASFIYLRLKSNYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRVVGRTICLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNRS--VITEFILVGFSNLG-DLQIL----LFIIFLL-VY
LTTLMANVT-IMTVIRLDRSLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLSNLLATNP-SISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRAACVQLVLASSFCGFLI----SVVVNILVFTVPFCASNRVNH-FFCDVSP
-VMKLGCTD-TNLKGMVIFFLSILVLLVPFVLICISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASSIYLRPTSLH-S--SDKDL--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KMA---LRK------VLSRYSFPKTV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCASQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSPRDCAHLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FVCHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIVAAILRIPSAAGRHKT----
-----F--------------STCVSHLTV-VVTHYSFASLIYLKPKGFH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------NFFRKFCPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VP-KPNST--FVTEFLFEGFSSFRWQHRLV----FFVVFLT-LY
LLTLSGNMI-IMTIVRLDHHLHT--PMYFFLSMLSISETCYT--VA--------------
I-TPH---MLSGLLNPHH-PVATPSCATQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRYSVIMSKSACIHLASVSLGIGLAC----NICVWPAI-----LICLVISH-FFCDVRP
-LLKLACTD-TTVNEIINFIVSVCVFVPPMGLVFISYVLMISTILTIASAEGRKKA----
-----F--------------AT------L-VIIHYGCASFIYLKPKSQS---SLGQDR--
-LIAVTYT----------------P---EQQ---G-G---QRC------SAQSHGAKDPV
SLTKR-------------GCEAFFFEFISMC

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--STSEFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSQRSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSAQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICR
PLRYNVLMSPRGGACLMGCSWAGGSVM----GLVVTTAIFHLTFCGPSEIHH-FFCHVPP
-LLKLACGDDVLVVAKGVGSVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVAMVAMKK------TFFATLFPQNC
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANHS--TVTQFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSAQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICR
PLRYNVLMSPRGGACLVGCSWAGGSVM----GLVVTTAIFHLTFCGPSEIHH-FACHVPP
-LLKLACGNNVPAVALGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLNPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MK-------TFFSKLYPEKN
V---T-I------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVILAENLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LIILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFNCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPTLMSWQVCGKLTAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VILLACTN-TDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLSV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVSEFIFLGFSSFG-KHQIT----LFVVFLT-VY
ILTLVANII-IVTIICIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLLSLIFHNQ-PISLAGCATQMFF-FVILAT-NNCFLLTAMGYDRYV-AICR
PLRYTVIMSKGLCAQLVCGSFGIGPTM----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCTD-TTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKT----
-----F--------------ATCASHLTV-VIVHCGCASIAYLKLKSES---SIEKDL--
-VLSVMYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MH-RKNLT--EVTEFVFLGFSRFH-EHQIT----LFVVFLI-LY
TLTLAGNVI-IVTIIRIDHHLHT--PMYFFLNMLASSETVYT--LV--------------
I-IPR---MLSSLVAQNQ-PISLAGCITQMFF-FVTLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMSKRVCVQLTCGAFGIGLAM----AAVQVTSIFTLPFCHRV-VGH-FFCDILP
-VMKLACTD-TTINEIINLVVSLFVILVPMGLVFISYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SVEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRHIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNCT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTL------------------------------VMGYDRYV-AICH
PLRYNVFMSPRGCACLVVWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGEHVLEVAKGVGIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KSA---MKK------IFLSKLYPE--
----------KI-------------------

----------------------MERGNETLVREFIFLGFSSLAGLQ--RLLFVAFLPLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFV
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTELMGPRVCVGLVAAACACGLTI
AQIVTSLVFHLPFLSSNQLHHYFCDISPVLKVASHHSRLSQLVIFMIGVCVLVVPLLLIL
VSYIRIISAILK-IPSSTGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSSYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNQEFKAAFRRVMGQTLYPPH--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------SS-SQNYS--TVSEFILIGFSSFPQHFLPT----FFLLFLM-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLADMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWCWAGGSVM----GMILTLIVFHLTFCGSNEIHH-YGCHVFA
-LLKLACGKETASVTMGVILVCVTALMGCLFLIFLSYVFIVAAILRIPSNEGRHKT----
-----F--------------STCVSHLTI-VVVHYSFASIIYLKPKGPH---SMDSNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KIA---IQR------SFHRKFSSLGS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNCT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVFMSPRGCACLVVWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGEHVLEVAKGVGIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KSA---MKK------IFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------SA-AQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLADMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWCWAGGSAM----GMMLTLIVFHLTFCGSKEIHH-FVCHVLS
-LLKLACGKETASVTMGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------SFRRTFHPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-TANCK--EIKEFVFQGFSNFQ-EHQLT----LFMVFLA-LY
ILTLAGNII-IVTIIRIDHHLHI--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLSGLVGLSQ-SISLECCGTQLFF-FLGFAI-TNCLLLAVMGYDCYV-AICN
PLRYSIIMNWRVCIMLASSVCATGFLL----SLLQAVVIFRLPFCSSL-IEH-FFCDVRP
-VLDLACAI-PIINDILTLIISLLAITAPSTFLFISYILIISTIFKIASAEGRKKT----
-----F--------------ATC---------------------PKSKN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNEEV---QDA---LCR------VVGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LP-GQNWS--MVTEFILIGFSTFPQHLLPI----FFFLYLL-MY
LFTLLGNLL-IMATIWSEHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLVDMLSTHH-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLCYNVLMGTRGFVRLVSWSWAGGSVM----GMMVTLIVFHLTFCGSNTIHH-FFCHVLS
-LLKLSCGKEASSVTLGVILVCVTALMGCLFLIFLSYVFIVAAILRIPSAEGRHRT----
-----F--------------STCVSHLTV-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVV-TPFL----SPIIFSLRNKEL---KNA---IKK------SFLRKFCPLNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-LSNAT--SWRGFVFLGFSSFG-DLQLL----LFAIFLS-LY
LITLTSNVF-IILVIRLDSHLHI--PMYLFLSYLSFSETCYT--LG--------------
I-IPR---MLSGLVMGDQ-AISYVGCATQMFF-SASWAC-TNCFLLTVMGFDRYV-AICA
PLHYVSRMHPTLCAQLVVTSFLGGYLF----GLGMTLVIFRLPFCSSHEIQH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLISFSLLTISYAYILSAILRIPSAEGRKKA----
-----F--------------STCASHLTV-VIVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LK-------NAFQGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MR-QFNAT--YWKGFVFLGFSSFG-NLQLL----LFALFLS-LY
LVTLTSNVF-IIIIIRLDTHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLFGLVMGVQ-AISYVGCATQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYTSRMSPTLCVQLISISFLSGYLF----GLGMTLVIFCLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TELSELGILILSLLVLLVSFFFIVISYAYILVAILKIPSADGRRKA----
-----F--------------STCASHLTV-------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--MITEFILVGFSNLG-EMQIL----LFFIFLL-VY
LTTLTANAT-IMTVIRLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-IPN---MLANLLSTSP-TISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYMLI--------LVLASSLCGFLI----SVVVNVLVFSVPFCSSNRINH-FFCDISP
-VLKLGCTD-THLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDL--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KVA---LRK------VLSRYSLPK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--MITELILIGFSNLG-DLQIL----LFFIFLL-VY
LTTLSANAT-IMTVIRLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTAP-TISLSGCVAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLIVSRATCTQLVLASSFCGFLI----SVVVNVLVFSIPFCASNRINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPLVLIFISYVFIVSTILKISSVEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LKK------VLSRYLLSKTV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------VCLQAAERLWGNGSR--LVTEFVLVGFSHLP-HLRIT----LFTLFFL-TY
LVTLSGNAT-IITVIQADRTLHT--PMYRFLALLSLSETCYT--LV--------------
T-IPN---MLAHLLTERH-AISVPACRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICC
PLRYSVVMRPTVCLCLGAVVFCSGFSV----AMIETCMIFSSPFCRGSRVEH-FFCDIAP
-VLRLSCTQ-STGRALGIFFLSVLVVLASFLLILLSYAFIVATILRMPSATSRHKA----
-----F--------------STCAAHLTV-VLVHFGCAGVIYLRPDSGA-H--PERDR--
-LVAVFYTVV-TPLL----NPVVYTLRNREV---RVA---LRR------TLARGCGAEQR
GPA-DRHS-----------------------

SFSGIFLGTVFPLRLSPDDISSMECVNETLVREFVFLGFSSLAGLQ--RLLFAAFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLTVLSCFETCYTFVIVPKMLVDLLAQKKTISFL
GCAMQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTVLMGHGVCVGLVAAACACGFIV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLKVASYHTHFSQIVIIMLCALVLIIPLLLIL
VSYIRIISAILQ-FPSTLGRYKAFSTCASHLIIVIVHYGCASFIYLRLKSNYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRVVGRTICLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------M--ASDRICAGGFSNLP-HLRTT----LFTLLLL-TY
LVTLSGNVT-IITIVHVDRTLHK--PMYRFL-----------------------------
-----------------------------MFF-FLGLGC-SHCFFLTLMGYDRFV-AICH
PLRYSVIMRPTICVRLGASVFCSGFSV----ALIETCMIFSSPFCRGDRVER-FFCDIAP
-VLRLSCTQ-GASKALGIFFLSVLVVLFSFLLILLSYAFIVATVVKMPSATGRHKA----
-----F--------------STCAAHLTV-VMVHFGCAAIIYLRPDSG---AHPEQDR--
-PVAVFYTVA-TPLL----NPVVYTLRNKEV---RVA---LRR------SLARGCGVWHK
HALSL----IHG-TLGFH-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------IEEE---ERSASV-IS--EKYLELIYGINT---DSPIN----IFLLFTQTTD
LDILVANGS-IMVAITLSRNLHT--PMYFFLCGLSLSETCAT--VV--------------
I-IPR---MLVDLVSESS-IISLPECATQMLC-FLCLAA-NNCFIMAAMSYDRYT-AIHN
PLNYHMLMTGKICCQLMTASLVTGFLI----SLGIVLTAFNLPFCGSKIIHH-FFCDISP
-VVLLACGY-TFFHEMVIFVLSALVLVGSFILIMVSYVFIVSVVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFACSVYLKLKNS---ASFHEDM--
-LMAVTYTVL-TPLL----NSIVYSLRNREM---QTS---LWK------LINRATNSLIS
LPQRINSKNTSE-PFKMHS------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHT--SMSEFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCVLSVSEILYT--VA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVGCSWAGGSVM----GMVVTSAIFQLTFCGSHEIQH-FLCHVPP
-LLKLACGNNVPAVALGVGLVCIMALLGCFLLILLSYAFIVADILKIPSAEGRNKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGPH---SQEGDT--
-LMATTYAVL-TPFL----SPIIFSLRNKEL---KVA---MKR------TFLSTLYSSGT
-------------------------------

----------------------MERVNETVVREFIFLSFSSAARLQ--QLLFVIFLLLYL
FTLGINAII-ISTIVLDRALHIPMYFFLAILSCSEICYTFVIVPKMLVDLLAQRKTISFL
GCAIQMFSFLFLGCSHSFLLAVMGYDRYVAICNPLRYSVLMGHGMCMGLVAAACACGFTV
AQIITSLVFHQPFYSSNQLHHFFCDISPVLRLASHHNHFSQIVIFMLCTLVLAIPLLLIL
VSYVHIISAILQ-FPSTLGRYKAYSTCVSHLIIVTVHYGCASFIYLRPQSNYSSSQDALI
SVSYTIITPLFNPM-IYSLRNKEFKSALCRIVRRTISLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MV--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFF-FFGLGG-NNCFILAAMSYDRYI-AIHN
PLHYPMLMTKKICFQLIMASCIVGFLV----SLSIVIIIFTFSFCDSYTVQH-FFCDILP
-VANLACDY-TSFHEMAIFMLCAFVLVGSFILIVISYVFILSLVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFACYIYLRPKSS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QVA---LWK------VLENGHRFISR
W------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------PWKQLPLENFT--MVTEFLLLGFSNLN-KMQFV----LFGVILC-LY
LIILSGNIT-VITTICLEHSLHT--PMYFFLSVLSVSETLYT--LV--------------
V-LPK---MLLNLLSVLR-TISFTSCAAQMFF-LLGFAT-TNCLLLGVMGYDRYT-AICH
PLRYPVLMSWWICKLMATTCGVSGILV----SIFVTFLVFSLPFCNSNRINH-YYCDIAP
-VIRLACGD-RYINEAIILIAGIVVLVVPWMFICITYGFIIRTILRIPTTEGKKKA----
-----F--------------STCASHLIV-VVFHYGCASFVYLRPSSKH-T--SDKDK--
-LVTVTYTIF-TPLL----NPMVYTLRNREV---RVA---IQK------IWF-RCYCL--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-GENHT--LITEFVFQGFSSFH-EHQLT----LFVVFLA-FY
ILTLAGNVI-IVTIIRIDHHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-LPR---MLSSLVCVNE-SISLAGCATQMFF-FITFGI-TNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCVQLVWGAWSIGLIV----ATTQVISVFRLPFCAAK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCVSHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------VIGRKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFI-LGFSSLG-KHQIT----ISGVFLT-VC
ILTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEMVYT--LV--------------
I-V---------LIFHNQ-RISLAGCATQMFF-FVILAI-NNCFLLTAMGYDCYV-AVCR
PLRYTVIISKGLCAQLVCGSFGI--------------AMFSLPFCGTV-VDH-FFCDIYP
-VMKLSCID-ITIDEIINYGVS---------LIFTSYVLIISFILKIASTEGWK-T----
-----F--------------ATCASHLTV-VIVHRGCSSTTYLKPKSEN---STEQDL--
-LLSVTYTII-APLL----NPVVYSLRNKEV---KDA---LCR------VVGRNISKHIG
LLNQE-------------TVSPV--------

----------------------MECVNDTVVREFVFLGFSSLAELQ--LLLFAVFLSLYL
FTLSTNAVI-VSTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLARKKSISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICHPLRYTVLMGHRVCVGLVAAACVCGFTV
AQVITSLVFRLPFRSSNQLHHFFCDISPVLQLASHHPHSTQITIFLLCALVLVIPLLLIL
VSYIHIISTILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSSYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKDFKSALHRVIGRTVTLRQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LLISLRPQPPSMP-KPNST--SVAEFLFEGFSSFGRQHRLG----LFVVFLT-LY
LLTLSGNAV-ILTIIRLDRHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPC---MLSGLLSPHQ-TISLQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYM-AICN
PLRYSVIMGKEACIQLATGSLGIGLSM----AIVQVTSVFGLPFCDAFIISH-FFCDVRP
-LLKLACTD-TTINEIINFFVSICVLVVPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLIV-VIIHYGCASIIYLKPKSQS---SLGQDS--
-LISVTYTVI-TPLL----NPVVYSLRNQDV---KDA---LCR------AMGRKPLSSQ-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQVFNKTT--VVTQFILVGLSSLQ-ELQLL----LFVIFLF-LY
LTILMANAT-IMAVIRYSRTLHT--PMYGFLFILSLSESCYT--FV--------------
I-IPQ---LLVHLLSATK-TISFMACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLTSLSGVTGFLI----ALVATNLIRDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMAPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLGMPMATKVA
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------M-LKNST--FVTEFLFEGFSSFGWQHRLV----FFIVFLT-LY
LLTLSGNVI-IVTIIRLDRHLHT--PMYFFLSLLSISETFYT--IA--------------
I-IPR---MLSGLLSPHQ-AIDIQSCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKACIYLACGSLGIGLGM----AIVQVTSVFGLPFCDGFIIAH-FFCDVRP
-LLKLACTD-TTINDIINLVVSVCVLVLPMGLVFISYVVIISTILKIASVEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KEA---LRK------AIGLRPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-GQNYS--TMSEFILIGFSNFPQHLLPT----FFLLYLL-MY
LFTLLGNLL-IMATIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLVDMLSVHR-SISFVAYASQKFF-SFTFGF-THSFLLMSMGYDHYV-AICH
PLRYNVLMRPGGCARLVSWSWADGSVM----GMMLTLIVFHLTFCGSNEIHH-FACHVLA
-LLKLACGNETSSVTMGVILVCVTALMGCLFHIVLSYVFILAAI----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TASTFLLWGFSSFP-DLQGL----LFVVIFF-SH
VTILAANVC-IMVAIKLSHNLHT--PMYFFLCGLSFSETCTT--MA--------------
I-IPR---MLVDLLSDSK-AISLPECATQMFF-FFGLGA-NNCFIMAAMSYDRYT-AIHS
PLHYKVLMTHKICFQFMMASWMAGFLV----SLCIVITVFNLSFCDSNIIEH-FFCDISP
-VVCLACDY-TSHHEMAIFVLSAFVLVGSFVFIMMSYVFIVSRVVKMPSAKGKYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKDM---QTA---LRK------VLGKTNRFIPQ
MGSRRTLDIKN------------VQTVDK--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NQT--ILKELMRVGFSLYP-QVQTF----LFFVFWC-LY
LLTLAGNLT-IMGLTWVDRSLHI--PMCLFLSALSFFETCYT--LT--------------
I-IPK---VLKDLQTENR-SISVTGCGLKMYF-LLGLGG-TNRIILTLMGYDRFL-AIHN
PLRYPLLMTNAACGRPVASAWAGGFSI----SLVETALIFRVSFRLPNLVRH-FFCHMQA
-VVRLSCMD-SELTEFIVTAI----LLGTFLLSILTYVFILSSILRMSSSEGKQKA----
-----F--------------STCASLLTV-VIIHFGSASIVYQKPGAS-----QRVDA--
-LIAVPYTII-ITTF----LPIIFGLRNKDI---KNA---FRK------IMRKITALKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TLSDFVLFGFSAFPQQLLPA----LFLLYLL-MY
LFTLLGNLL-IMATVWTQRRLHT--PMYLFLCALSTSEILFT--VV--------------
I-TPR---MLGDLLSSHH-SITFVACATQMFF-SFAFGY-AHSFLLMVMGYDRYV-AICH
PLRYNVLMSPAGCAHLMAWSWAGGSVM----GVIVTLIVFHLTFCESNVIHH-ILCHVFS
-LLKLACGDETGFITMGVILVCVIPLIGCLSLIILSYVFIVATILRIPSPEGRHKT----
-----F--------------STCVSHLTV-VVVHYGFASMIYLKPKGPH---SVYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------TFYRKFCLQIS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-ESNVT--CWQGFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTVCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGSLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LS-SQNYS--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VT--------------
I-TPE---MLVDMLSTHH-SITFVACASQMFF-SFMFGY-THSFLLMIMGYDRYV-AICH
PLHYNVLMSTRDCARLVSWCWAGGSVM----GMMVTLIVFLLTFCGSNEIHH-FFCHIFS
-LLKLACGRDTASLTLAVILVCVTALIGCLFLIVLSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPR---SMDSNI--
-LMTTTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKR------SFRRTFCPLNS
-------------------------------

----------------------MERANETLVREFVFLGFSSLARMQ--LLLFIVFLLLYL
FTLGTNAII-ISTIVLDRALHNPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFFGCSHSFLLAAMGYDRYMAICNPLRYTVLMGHGLCVGLVAAACACGFIV
AQIITSLIFHLPFHSSNQLHHFFCDISPVLKLASHHSLFSQLVIFMLGMFVLVIPLLLIM
ISYIHIISALLK-ISTSAGRYKTFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDILI
SVSHTILTPLFNPM-IYSLRNKEFKSAIRRVVRQVSYPVK--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------M-PKRNH--TVSEFILIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWRKRSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLADMLSTHR-SITFVACACQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSCCWAGGSVM----GMVLTLIIFHLTFCGSNEIHH-FGCHVFA
-LLKLACGKGTASVSMGVILVCVTALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPH---SMESNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KIA---IQR------SFHRKFSSLVC
K---QP-------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSAFPQQLLPV----LFL-------
--------------------LHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHH-SITFVSCAGQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYKVLMSPRDCARLVAWTWAGGSVM----GMMVTMIVFHLSFCGSNVIHH-FVCHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLLLIILSYVFIVAAILRIPCAEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFPSLFYLKPKGFH---SMYSDA--
-LMATTCTVF-TPFL----SPIIFSLRNKKL---KNA---INK------NFYRKFCLLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VPGMKLENETW--IVKEFVLVGFSNLP-DLKAT----LFILFLL-MY
LISLSSNVT-IITIIYLDHTLHT--PMYCFLGVLSLSETCYT--LV--------------
T-IPN---MLVHLLMANQ-VISIPSCRTQMFF-FIGLGC-SNCFLLTLMGYDRYV-AICH
PLRYTVIMSPSVCLHLGSLVFCSGFLV----AVTETCLIFSSSFCHSNQVEH-FFCDIAP
-VLKLSCTQ-SAAKALTIFFFSVIVLLASFLLILLSYAFIVAAIVRIPSAAGRRKA----
-----F--------------STCVSHLTV-VIVHFGCASIIYLRPESGS-N--PDQDR--
-MVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LKR------TLGRRLRTQNN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PENFT--MVTEFLLLGFSNLQ-ELQLV----LFAVFFC-LY
IIILCGNIT-IVTVILLEHNLHT--PMYFFLGVLSVSEICYT--FV--------------
I-LPK---MLLNLLSLLR-TISFTSCAIQMFF-FLSFAI-NNCLLLSVMGYDRYA-AICH
PLRYSVLMNWGTCRLLAATCGVSGILI----SVVGTTLVFILPFCNSNKVNH-YFCDISP
-LIHLACGD-THVNEMTIFICGVLVLVVPLLFVCISYGFVVRTILRIPSTVGKQKA----
-----F--------------STCASHLTV-VIVHYEC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RQNFT--EVKEFIFLGFSSFG-KHQIT----LFVVFLT-VY
LFTLAGNVI-IVTIIRIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSNLLFHNQ-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICN
PLRYTVIMSKGMCARLVCGSFGTGLAM----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVIFVPIGLIIISYVLIISSIFKIASAEGRKKT----
-----F--------------ATCTSHLTV-VTVHYGCASIAYLKPKSES---SIEKDL--
-LLSVTYTIV-TPLL----NPVVYSLRNKEV---KDA---LSR------AVGRNVS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILFGFSAFPHQMLPA----LFLLYLL-MY
LFTLLGNLV-IMAAIWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLSDLLSTHR-SITFIACANQLFF-SFTFGY-THSFLLVVMGYDRYV-AICR
PLHYHVLMSLQGCARLVAWSWAGGSLI----GMTLTIIIFHLTFCESNVIHH-ILCHVFS
-LLKLACGERTAFVTIAVILVCVTPLIGCLIFIILSYIFIVAAILRIPSTEGRHKT----
-----F--------------STCASHLTV-VIVHYGFASIIYLKSRGLY---SLYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---IIK------SFHRNFCQQSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------FLLTAMGYDRYV-AICN
PLRYMVIMSKRVCAQLVCGACGIGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCDD-TTLHDIINLIVSSLVIVVPMGWVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TKDQDQ--
-LISVTYTVF-TPLL----NPV--------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-EVNHS--TVSEFVLVGFSTFPQLQ-LV----FFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTSH-SIAFMACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLRYKVLMSPQGCACLVIWSWAGGSVM----GMVVTTGIFNLTFCGPNEIHH-FACHVPP
-MLKLACGNDVPAVARGVGLVCITALLGCCLLILLSYAFIVAAILKIPSTEGRHKV----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPQ---SLEGDT--
-FMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---IKK------TYLSKPSPQTV
----T-LW-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-HHQMT----LFAVFLT-IY
ILTLAGNIT-IVTIACMDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFHNL-AISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICD
PLRYMVIMSKGMCAWLVCGSLGTGLVM----AVLHVPAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTLNEIINYGVSSFVILVPIGLIFISYVLIISSILKIASTEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VP-MPNST--AVTEFLLEGFSSFGWQHRLV----FFAVFLT-LY
LLTLCGNVI-IVTIIHLDRHLHT--PMYFFLSMLSLSETCYT--VA--------------
I-IPR---MLSGLLNPHQ-PIAVQGCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMSKETCVQLAYGSLGIGLSM----AIIQVTSVFGLPFCDAFVISH-FFCDVRP
-LLKLACMD-TTVNEIINFVVSVCVLVLPMGLVFISYVLIISTILKITSAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LLSVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LHR------AVGRNLSS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--TITEFILIGFSNLG-DLQIL----LFFIFLL-VY
LTTLMANTT-IMTVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPN---MLTNLLSTSP-TISVPACAAQLYF-FVGLAC-TNCFLIAVMGYDRYA-AICN
PLNYTLIV------------NFCGFLV----SVVVNVLVFSVPFCASNQINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYVFIVST-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MKGFNRTT--VVSQFILVGFSSLG-ELQLL----LFVIFLL-LY
LTILVANAT-IMTVICLSRTLHT--PMYGFLFILSFSESSYT--FV--------------
I-IPQ---LLVHLLSATK-TISFTACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLVSLSGVTGFFI----ALVATNLICDMPFCGPNMVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMMPFLLILISYGFIVNTILKIPSTEGKRKS----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKPKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VVGMPVVTKLI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSQ-SISLGGCATQMFF-FVTFGI-TNCFLLTVMGYDHYV-PICK
PLRYTIIMNKKGCIQLVLGPCSIGLIV----AMTQVSAMFRLPFCATE-VAH-FFFDIQP
-VMKLSCID-ATVSEILTLIISVLVLVVPM---------------------GRKKA----
-----F--------------ATCTSHFTV-VSVHYGCASITYLKPKSKN---SRDEDQ--
-LISVTYTVI-TPVL----NPVVYTLRNKEV---KNA---LCRA------TDRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------VVLFGNLTVK-TENHT--GVREFIFQGFTSFH-EHKLT----LFVVFLT-LY
LLTLSGNVI-IVTIISIDRHLHT--PMYFFL-----------------------------
---------MSSLAGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYMIIINKRVCAQLVWGACSIGLFV----ATIQISSVFRLSFCYRK-VAH-YFCDIRP
-VMKLSCAN-TTIHDIINFLVSSLVIVVPMVLVFISYIPIISTIFKIASAEGRKKA----
-----F--------------ATCASHLMV-VIVHYGCASIAYLKPKSEN---MRDQDQ--
-LISVTYTVF-TPLL----YPVVYTLRNKEV---KDA---LCR------AIGKKTL----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENQS--IITDFFLIGFSNLG-HLQIL----LFFVFLL-VY
LTTLMANAT-IMTVIRLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLS-TP-AISFSGCVTQLYF-FVGFAC-TNCFLIAVMGYDRYI-AICN
PLNYTLII------------SFCGFLI----SVVVNVLVFSVPFCASNRVNH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYIFIVSTILKISSVEGQRKT----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDS--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KSA---LRK------VLGRYSLPK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MSN-HT--TVSTFLLWGFSSFP-DLRGL----LFVMIFF-SH
GIILTANVS-IMVAVKLSHNLHT--PMYFFLCGLSFSETCST--MA--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFV-FFGLAA-NNCFIMAAMSYDRYT-AIHK
PLHYPILMTHKICFQFITASWMVGFLV----SLGIVIVVFSLSFCDSNIIQH-FFCDISP
-VVSLACDY-TSRHEMVIFGLSAFVLVGSCVFIVMSYVFIVSTVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DSFCEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLGKTGSSLRG
LLINKKSKHVF------------TTVFS---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KENHT--LVSAFVLQGFSSFH-EHQLT----LFVVFLA-LY
ILTLAGNVI-IVTIIGLDRHLHT--PMYFFLSMLSASETVYT--LV--------------
I-IPR---MLSSLIGLNQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMKKSVCIQLVWGACSTGLAV----AVTQVCAVFRLPFCDSE-VAH-FFCDIRP
-VMKLSCID-ITVNEILTLIISVLVILIPMGLIFISYILIVSTILKIASAEGRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TKDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KEA---LCR------AIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------IR-VKNFT--EVTEFIFLGFSRFH-DHRIT----LFVVFLI-LY
TLTLTGNAI-IVTIIRIDRHLHT--PMYFFLSMLATSETVYT--LV--------------
I-IPR---MLASLITPNQ-PISLPGCTTQMFF-FVTLAI-NNCFLLTVMGYDRYV-AICN
PLRYTVIMSKRACIQLMCAAFGIGLAM----AAIQVTSIFTLPFCHRV-VGH-FFCDILP
-VMKLSCID-TTVNEIINFVVSLFVILVPMGLVFISYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSDN---SVEQDL--
-LLSVTY-----------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------LPY---
TLIYVLNVCYVFFQTSII-RQNQS--ELTEFILTGFSELG-DLQIL----LFFVFLL-VY
LTTLMANAT-IMTVIRLDRALHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTIP-TISFSGCAVQLYL-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLN------RATCMQLVLASSFCGFLI----SMIVSILVFSVPFCASNRINH-FFCDISP
-VIKLGCTD-TSLKEMIVFFLSILVLLVPLVLIFISYIFIVSAILKISSVERQYKA----
-----F--------------ATCASHLTV-VIIHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTT---LRK------VLSRCSYS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHTLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCVSQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSPHDCARLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FVCHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIMAATLRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYSFASLIYLKPKGLH---SMYSDT--
-LMATTYTVF-TPFL----SPIIFSL----------------------------------
-------------------------------

----------------------MERNNLTAVSEFVFLGFSALAGFQ--RLLFVLFLLLYL
FTLSTNAVI-LSTILLERALHTPMYFFLGILSCFETCYTFVIVPKMLIDLLSQKKTISFL
GCIVQMLTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMSHGTCLGLVAAACACGFTV
ALIITSLVFHLPFHSSNQLHHFFCDISPVLKLASHHTSLSQMIIFMLSVLVLVIPLLLIL
VSYIRIISAILK-IPSTVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKTNYISSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKAALWRAMGQNLCPKIA-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TTSEFILFSFSAFPHQLLPA----LFLLYLL-MY
LFTLLGNLL-IMATVWTERQLHT--PMYLFLCALSISEILFT--IA--------------
I-TPR---MLADLLSTHH-SITFVACAMQTFF-CFTFGY-AHSFLLMVMGYDRYV-AICY
PLSYNVFMSPTVCAHLVTWSWAGGSVM----GMIMTSIVFHLTFCESHVIHC-ILFHEFS
-LLKLACGDEMGSVTIGVILVCVIPLVGCLSLIILSYVVIVSAILRIPSPEGRHEI----
-----F--------------STCVSHLTI-VIVHYSFASMIYLKPKGPH---SIYTNT--
-LMSTIYIVF-TPFL----SPIIFSLRNKEL---KTS---INK------NYHRKLCLQNP
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LIVFFYLYLLTWNLPMK-RENYT--VVSEFFFQGFSSFH-EHKLI----LFAIFLT-LY
ILTLAGNII-IVTIISTDRHLHT--PMYFFLSMLSTSETMYT--LV--------------
I-VPQ---MLSSLIGQSH-AISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICK
PLRYTVIMNKKVCAQLVWGACSIGLLV----AIIQTPSVFSQPFCGKE-VAH-YFCDIRP
-VMKLSCAD-NNLHDIITFIISSLVIVLPMGLVFISYILIISTILKIASSEGQKKA----
-----F--------------ATCASHLIV-VIVHYGCASIAYLKPESEN---TKDQDQ--
-LISVTYTIF-TPLL----NPVVYTLRNKEV---KNA---LHR------AFSRKPLFILY
S------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LSMANSS--FVTEFLLMGFSSLG-KLQLV----LFVVFLS-LY
LIILTGNIT-IISVIRLDHNLHT--PMYFFLCVLSISETLYT--IV--------------
I-LPK---MLFNLLSVLR-TLSFTSCATQMFF-FLGFAL-NNSFILGVMGYDRYA-AICQ
PLHYPILMSWKVCGQLAVISVICGFLT----SLVATVLVFSLPFCGPNKVDH-YFCDISP
-VIRLACAN-AHVNELVIFIGGALVLLVPLLFICISYGFIVHTILRIPSTEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASSVYLRPSVKH-T--SSKNS--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QMA---IKK------M----------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RNNIS--KVTEFVFLGFSSFH-DHQIT----LFVIFLI-LY
TLTLAGNAI-IVTIIRIDRHLHT--PMYFFLSMLASSETVYT--LV--------------
I-IPR---MLSSLISQNH-PISLAGCTTQMFF-FVTLAI-NNCFLLTVMSYDRYV-AICN
PLRYAVIMSKRMCVQLMCGALGIGLIM----AAVQVASIFTLPFCHRV-VGH-FFCDILP
-VMKLSCID-TTINEIINFVVSLLVILVPMGLVFISYVLIISTILKIASAEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SVEQDL--
-LLSVTY-----------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSKVILAENVT--MVTEFLLLGFSSLG-EIQPA----LFVVFLF-LY
LAILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGLMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPVVYSLRNKDV---QLA---IRK------VLGKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------LREEERGT-DG--MGSKYLLCEMH--T-DS-PT-----RIVLHLTHA
PGISAANVL-IMVAIKLSHNLHT--PMYFFLCGLSFSETCTT--MV--------------
I-IPR---MLADLLSGTK-MISFPECAAQMFF-FFGLSS-NNCFILTAMSYDRYI-AIHN
PLNYHMLMTRKICFQQIMASFSVGILV----SLTIVCTVFNLSFCDSKTIQH-FFCDISP
-VVLLACDY-TFFHEMVIFVLCAFVLVGSFILIMVSYVFIVSVVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFACSVYLKPRNS---ASFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNREM---QTA---LWK------VMGSANRLTQK
-IKKEPAHKTVV-V-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------PENLT--MVSEFLLLGFSNLQ-ELQLV----LFAVFFC-LY
IIILCGNIT-IVTVILLEHNLHT--PMYFFLGVLSVSETCYT--FV--------------
I-LPK---MLLNLLSLFR-SISFTSCAIQMFF-FLSFAI-NNCLLLGVMGYDRYA-AICH
PLRYPVVMNWGTCRLLAATCGVSGSLI----SMVCTTLVFILPFCNSNKVNH-YFCDISP
-LIHLACGD-THVNEMTIFICGVLVLVVPLIFVCISYGFIVRAILRIPSTEGKQKA----
-----F--------------STCASHLTV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNSS--FVTELLFEGFSSFRRQHKLV----FFVVFLT-LY
LLTLSGNVI-IMTIIRLDHHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPH---MLSGLLNPHQ-PIATQSCATQLLF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRYSVIMGKRACIQLASGSLGIGIGM----AIVQVTSVFGLPFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSICVLVLPMGLVFISYVLIISTILKIASAEGWKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYSHH-SPTE----PCCVQP---EEQ---G-G---QRC------SAQSRGAKDSV
SLMKR-------------GCEGFSFAFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MIASQCFS--FS--------------
IPISS---FSTH----AS-SEVFSFIFNSRCF-LLGLAS-NNCFIMAAMSYDRYT-AIQN
PLHYHTLMTRTICFQLLMASAVAGFLI----SLCITTMIFNLSFCDSNNIRH-FFCDISP
-VVHLACDY-TSYREMVIFVLSAFVLVGSFILIMISYIFIVFIVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCVHYGFACFVYLRPKSS---DSFTGDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRR------VLQGVFKFFSQ
LTNRKP-LNI---------------------

----------------------MERTNETAVNEFIFLGFSSLAGFQ--WLLFVLFLLLYL
FTLGTNAVI-LSTILLERALHTPMYFFLGILSCFETCYTFVIVPKMLVDLLAQKKTISFW
GCVVQMLTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMSHRTCLGLVASACVCGFTV
ALIITTLVFHLPFHSSNQLHHFFCDISPVLKLASHHTSLSQMIIFLLSVLVLVIPLLLIL
ISYIYIISAILK-IPSTVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKTNYTSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKTALWRAMGQNLCPKLAGTTS---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-EANFS--AVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWSERGLHT--PMYLFLCTLSTSEVLYT--FA--------------
I-IPR---MLADLLSTDR-SISFRACASQMFF-SFTPGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGLVV----GLVVTSSIFQLTFCGSNEIRY-FGCHVLP
-LFKLACGDNVSTVAMGVGLVCIAALLGCGLLILLSYAFIVAAILRIPSAEGWHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIVFSLRNKEL---KEA---VKK------TFLKKKN---E
----M-IWEEFLGTD----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLTTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FTCHVPP
-LLKLACGENVLEVAKGVEIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------IFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MEEFVFPRLLILA-RLQQL----PLCYL-----
----------PAPLPVSFWSPSY--PLYFLLAILSCSETCYT--FV--------------
I-VPK---MLVDLLAQKK-TISFVGWCHPMFS-FLFLAV-PHSFLLAVMGYDRYV-AILN
PLRYSVLMGHGVCMGLVAAACACGFTV----SLVTTSLVFHLPFHSSNQLHH-FFCDISP
-VLKLASQH-SGLSQLVIFMLGVFVLVIPLLLILVSYVRIISAILKIPSPLGDTEP----
-----S--------------HLCLPSH-C-GNCSLRLCLFHLLKAKTN---YSSGQDT--
-LISVSYTIL-TPLF----NPVIYSLRNKEF---KSA---LRR------TIGQTLYSL--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MI-QNNAT--CLHDFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTITSNIF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-VISFMGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTVCAQLVGTSFLSGYLF----GMGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYVYILVAILRIPSADGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGNLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-RLNFT--AVTQFTFEGFSIFQWHHRLI----LFVVFLV-LY
LLTLTSNAI-ILTVIHLNRQLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPR---MLSNLLSPQQ-AISIPACATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSLIMGRKACLQLASGSWSIGLST----AIIQVSSVFSLPFCDASIISH-FFCDIRP
-LMKLACAD-TTSKEFITLLISLCVLVLPMVLIFISYVLIVTTILRMASAEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------VLGRKPLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENYT--VVNEFIFQGFSSFH-EHKLT----LFVIFLA-LY
LLTLAGNVI-IVTIISIDRHLHT--PMYFFLSALSTSETVYT--LV--------------
I-VPR---MLSSLLNLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCVQLVCGACGIGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCVD-TTLHDIVNFIVSSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LRR------AIGKKPLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNST--DVPEFLFEGFSAFGWQHRLV----FFVVFLT-LY
LLTLSGNVI-IVTIIRLDRRLHT--PMYFFLSLLSISETCYT--VA--------------
I-IPH---MLSGLLNPLQ-PIATQGCASQLFF-YLTFGI-NNCFLLTAMGYDRYV-R---
-----------ACVQLASGSLGIGLAM----AIVQVTSVFGLPFCDGFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMGLVFISYVLIISTILKIASAEGRKKV----
-----F--------------ATCASHLTV-VIIHYGCTSIIYLKPMSQS---SLGQER--
-LISVTYTVI-TPLL----NPGVYSLRNK-V---KDA---LHR------AMEQKSLTP--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSKVILAENVT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LAILSGSVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQTFF-FLGFAI-TNRLLLGLMGCDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPVVYSLRNKDV---KLA---IRK------VLGKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------IQNFNGSS--VVTHFILVGFSSLK-EFQLL----LFALFLL-LY
LTILVANAT-IMAVIRLSRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSATK-TISFTACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKSLGLGLVSLSAVTGFFI----ALVATNLICEMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFVLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIVYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LRR------VLGMPVATKV-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKKNQT--IVKEFIFVGFSLYP-DVQTL----LFVVFFS-LY
LLTLMGNLT-IMGLTWVDRTLHT--PMYIFLSALSFSETCYT--LS--------------
I-IPR---MLTDLLTADR-SISVIGCGLQMCF-FLGLGG-TSCIILTLMGYDRFL-AICN
PLRYPLLMTNILCGELVAFAWAGGFFV----SLIEMALIFRNFFCSPNLVKH-FFCHMRV
-VVRLSCLD-SNLTEFIVTLISVSGLLGTFLLIILTYVFILSTILRIPSSDGKQKA----
-----F--------------STCASHLTV-IIIHFGFASIVYLNPETS-----GEGDT--
-LISVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGKIVRLRY-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GVNRS--AVSEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATIWSKRSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---VLVDLLSTRH-AIAFVACASQMFF-SFMFGF-THSFLLTVMGYDRYM-AICH
PLRYNVLMSPQGCACLVVWSWAGGSVM----GMVVTIAIFNLTFCGPNKIHH-FACHVPP
-LLKLACGNDVPAVAKGVGLTCITALMGCCLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYSFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MNK------TFLSKLSPDKL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KPN-S--TMIEFLFEGFSNFGRQPRLV----LFVVFLT-LY
LLTLSGNII-IVTIIHLDRHLHT--PMYFFLSFLSISETFYT--VA--------------
I-IPR---MLSDLLSPHQ-PIAIQGCATQLFF-YLTFGI-NNCFLLIAMGYDRYV-AICN
PLRYSVIMSKRACVQLASGSLGIGLGM----AIVQVTSVFSLTFCDNFVISH-FFCDVRP
-LLKLACAD-TVINEIITFVVSVCVLVLPMGLVFISYVLIITTILKIASADGRKKA----
-----F--------------ATCASHITV-VIIHYGCSSIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LCR------AMGRKSFSL--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------CFFPIPDIQIMKTNQT--ILKEFVLVGFSVYP-HAQTF----LFVVFFC-LY
LLTLTGNLA-IMYLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLADLLAKNR-SITIIGCGLQMCF-FLGLGG-TNCVILTLMGFDRFL-AICN
PLRYPLLMTNMVCGQLVASACATGFFL----SVIETALIFRGSFCGPNLVKH-FCCHMRA
-VVRLSCLD-SELTEFIVMVISATALMGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIPYLKPGAS-----GGDDT--
-VIAVPYTVV-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGRTSSLNK-
-------------------------------

----------------------MEWVNETLVREFVFLGFSSLAGLQ--QLLFAVFLVVYL
FTLSTNAII-ISTIVLDRALHTPMYFFLAVLSCFETCYTFIIVPKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTVLMDYGMCLGLVAAACACGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASHYSRLSQLVIFMLGVFALIIPLLLIL
VSYIRIISAILK-ISSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRAMVQTSY-PVN-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AINQT--TLKEFILIGFSAYP-HVQTF----LFGVFFC-LY
ILTLAGNLT-IMGLTWVDRSLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPR---MLVDLLNNDR-HISVAGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWAGGFLI----SLIETALIFRVSFCIPNLIRH-FFCHMRA
-VVRLSCID-SDLTEFIVTLMSVSGLLGTFLLISLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFSLRNKDM---KAA---FRK------VMRKTIVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MLR------KKMPS
PLCVLSAQLSFSTG----------------AMSQKKCSTRPVPQKGEEKIIQVSTKATEK
PEQKIRIPIYRQTAPDKQWDNGTW--LVTEFVLVGFSNLP-ELRPT----LFTLFLL-TY
LVTLSGNAT-IITIIQVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-VISIAGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLCLGALVFCSGFSV----ALVETCMIFSSPFCGTGHVEH-FFCDIAP
-VLKLSCAE-STHKGLGIFFLSILVVLVSFLLILLSYAFIVVAILRIPSAAGRHKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPDSGA-N--PSQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRK------NLARGCGVFK-
-------------------------------

----------------------MERVNETVVREFIFLGFSSLARLL--QLLFVIFLLLYL
FTLGTNAIF-ISTIVLDRALHTPMYSFLAIFSCSETCYTFVIVSKMLVDLLAQKKTISFL
GCAIQMFSFFFLGCSHSFLLAAMGYDCYMAICNPWHYSVLMGHGMCMGLVAAACACGFTV
PLGTTFLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGLSQLVIFMLGIFALVIPLLLIL
HPHHLYL--VYLSLPSHCGNCSLW---------------LCFFHILKPKTNYSSREDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRTISQTLYPLN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MVPEKQQENATW--LVTEFLLVGFSNLP-DLRTT----LFALFFL-TY
LVTLSGNVT-IITVIHADRTLHT--PMYRFLAALSLSETCYT--LV--------------
T-IPN---MLARLWMEDQ-AISVSGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSLIMRPTVCLCLGALVFCSGFSV----ASIETSLIFSSRFCRSNRVEH-FFCDIAP
-VLKLSCAE-SASKALAIFFLSILVVLISFLLILLSYAFIVAALLRIPSAAGRSKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPESGG-N--PDQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRR------ILARSHVILK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--VITEFVLVGFSSLG-DLQIL----LFIIFLL-VY
LSILMANVT-IMTVIRLDRTLHT--PMYFFLFILSLSETCYT--LV--------------
I-IPK---MLTNLLSTEK-TISFSGCAAQLYF-FIALAC-TNCFLIAVMGYDRYV-AICN
PLNYMLIISRATCIQLVLTCAFCGFII----SVVVSILVFSLPFCASNRINH-FFCDVSP
-IMKLACTD-TKMKEMTFFFLSILVLLVPFVLIFISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCISHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPML----NPLVYTLRNKEV---KTA---LTK------VLSRYSFPKSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--CVTEFLLLGFSSLG-ELQLV----LFVIFLC-LY
LIILSGNLA-IISVICLDYSLHT--PMYFFLGVLSTSETFYT--IV--------------
I-LPK---MLINLLSVLR-TVSFMSCVFQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYAILMSWRVCGQLAVTCILGGFIV----SLVGTTLVFSLPFCGSHKVNH-YFCDISP
-VIRLACAD-TYINELIIFICGVLVLVVPLIFICISYGFIVSTVLKSSAE----------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-SGNHT--AVSEFVFQGFSSFH-EYKLI----LFVVFLT-LY
FLTLAGNVI-IVTIISIDRHLHT--PMYFFLSVLSTSETVYT--LV--------------
I-VPR---MLSSLIGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYMVLMNKRVCAQLVWGACSIGLLV----AMVQISSVFRLPFCERE-IGH-YFCDIRP
-VMKLSCAD-TTLHDIINFIISSLVIVVPMGLVLISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---FQR------VIGKKPLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MS-MPNSS--AVTQFLLEGFSSFGWHHRLV----FFVVFLT-LY
LLTLSGNVV-IVTIIRLDRHLHT--PMYFFLSMLSLSETCYT--VA--------------
I-IPR---MLSGLLIPQQ-PIAVQDCATQLFF-YLTFGI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMSKEVCVQLASGSLGIGLGM----AIVQVTSVFGLPFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LHR------AVGRRPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------RMKTNQT--ILKEFVLVGFSVYP-YAHTF----LSVVFFC-LY
LLTLTGNLA-IMYLTWVDRCLHT--PMYLFLSALSFSETCYT--LT--------------
I-TPK---MLADLLAKNR-SITIIGCGLQMCF-FLGLGG-TNCVILTLMGFDRFL-AICN
PLRYPLLMTNVVCGQLVVSAWVAGFII----SVTETALIFRGSFCGPNLVKH-FCCHMRA
-VVRLSCLD-SELTELIVTAISVSALMGTFLLIILTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPGAS-----GGDDT--
-VIAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FRK------VLGKTSSLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVTMFLLWGFSSFP-ELHNL----LFVVVLL-SH
VTILLANAF-IMVAIKLNHNLHA--PMYFFLFALSFSETCTT--MV--------------
I-LPR---LLVDLISKNK-AISLPECATQMFF-FFGLGG-NNCFILSAMSYDRYT-AIHN
PLHYPILMTQKICLHLIVASGVLGFSI----SLCIVITIFNLSFCNSNIIQH-FFCDIDP
-VVSLACNL-TFYHKVILFALTAFVLVGSFIFIMVSYVFIVTVVIKMPSAKGRYKT----
-----F--------------STCSSHFTV-VFIHYGFASFVYLRPKNS---YSFRDAT--
-LLAVTYTIL-TPLL----NPIIYSLRNKGI---QTA---LRK------DIGNIIRFFSK
MV-NKKAQKI---------------------

----------------------MECVNDTVVKEFVFLGFSSLAELQ--LLLFAVFLSLYL
FTLSTNAVI-VSTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLARKKSISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICHPLRYTVLMGHKVCVGLVVAACVCGFTV
AQVITSLVFRLPFRSSNQLHHFFCDISPVLQLASHHPHSTQITIFLLCALVLVIPLLLIL
ISYIHIISAILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSSYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKDFKSALHRVIGRTVTLRQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------TMKVNQT--VVGEFILIGFSVYP-HVQMF----LFLVFLG-LY
LLTLTGNLA-IMGLTWVDRSLHI--PMYLFLGALSFSETCYT--LT--------------
I-IPK---MLADLLTGNR-GISVTGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNMGCGRLVASAWAGGFLI----SLIETALIFRGSFCSPNLVRH-FFCHMRA
-VVRLSCLD-SDLTGSVVTVISVSGLIGTFLLIIITYMFILSTVFRIPSAEGKQKA----
-----F--------------STCASHLTV-VLVHFGFAAIVYLKPEAS-----GGDDT--
-LMAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---LRK------VLGKRRFLKKQ
FWI----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QANAT--AWKGFVFLGFSSFG-ELQFL----LFALFLL-LY
LATLTANVF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSSLVMGGQ-AISYVGCATQMFF-SASWAC-TDCFLLAVMGFDRYV-AICV
PLHYASRMSPAFCSQLVGTSFLSGYLF----GLGMTLVIFRLPFCGSHEIQH-FFCDTPP
-VLSLACGD-TGPSELGILILSLLVLLVSFSLITVSYAHILTAILRISSAEGRKKA----
-----F--------------STCVSHLTV-VVVHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------SAFRGRLLRGG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSLG-KHQIT----ISGVFLT-VC
ILTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEMVYT--LV--------------
I-V---------LIFHNQ-RISLAGCTTQMFF-FVILAI-NNCFLLTAMGYDCYV-AVCR
PLRYTVIISKGLCAQLVCGSFGI---------VLHVTAMFSLPFCGTV-VDH-FFCDIYP
-VMKLSCID-ITIDEIINYGVS---------LIFTSYVLIISFILKIASTEGWKKT----
-----F--------------ATCASHLTV-VIVHRGCSSTTYLKPKSEN---STEQDL--
-LLSVTHTII-APLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNAT--SWRGFVLLGFSNFG-ELQLL----FFALFFS-LY
LVTLTSNIF-IIIVIRLDSHLHM--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLILGDQ-AISYLGCAAQMFF-SASWAC-TNCFLLAVMGYDRYV-AICA
PLYYASRMNSILCAQLIGISFLSGYLF----GLGMTLIIFHLQFCSSHEIQH-FFCDTPP
-VLSLACGD-TDLSEIGILILSLLVLLVSFFFITISYAFILASILRIPSTEGKKKT----
-----F--------------STCASHLTV-VIVHYSCASFMYLKPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------KAFQGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------TEFLLLGFSSLG-EVQLI----LFAVFLC-LY
LIILSGNIT-IVTVIRLDHSLHI--PMYFFLGILSISETCYT--FV--------------
I-LPK---MLINLLSFLR-TISFIHCATQMFF-LLGFAT-TNCLLLGVMGYDRYA-AICH
PLRYPILMRWQVCGQLAATCAVVGFLF----SLIGSLLVFELPFCGPTKINH-YFCDISP
-VIRLACTD-TYIIELIIFAGGVLALTVPLTFICISYGFIVRTILRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASFVYLRPSAKY-S--SSKDK--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QTA---IRK------MICRG------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MAVTL-GLNHT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSALH-SIALLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGKNVLAVAKGVGMVCITALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLGGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKE------GLPK-------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HT--TVSTFLLWGFSSFS-DLQDL----LFVMIFF-SH
VTILAANTS-IMVAVKLSHNLHT--PMYFFLCGLSFSETCTT--VV--------------
V-IPR---MLVDLLSDSK-SISIPECATQMFF-FFGLGT-NNCFILAAMSYDRYT-AIHD
PLHYSSLMTHKICFQLMMASCMTGVVV----ALCIVLIVFNLSFCDSSIIQH-FFCDITP
-VVSLACDY-TIFQKMILLAFTAFVLVGSFILIMISYVFIGSIVMKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKSS---DSFREDM--
-LMALTYTVL-TPLL----NPIVYSLRNKEM---QTA---LKK------VRGSILNKTAL
NISKIFIVQALI-NKSRESEVIFVQLISCV-

----------------------MERVNETVVREFVFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAVI-VTTIVLDRALHTPMYFLLAILSCSETCYTFVIVPKMLVDLLAQKKTISFV
GCAIQMFSFLFLGCSHSFLLAAMGYDRYMAICNPLRYTVLMGHGVCMGLVAAACACGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGLSQLVIFMLGVFVLVIPLLLIL
VSYVRIISAILK-IPSSIGRYKTFSTCASHLIVVTVHYGCASFIYLRPKTNYSSGQDTLI
SVSYTILTPLFNPV-IYSLRNKEFKSALRRTIGQTLYSLN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MM-RRNHT--VISEFVFQGFSSFQ-EYKFT----LFMVFLT-LY
LLTLTGNAI-IMIIIGIDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLASLVGSSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRVCAQLVWGSCNIGLLV----AIIQIASVFRAPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTLHDIVNFIISSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IYR------AIGKNPLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-QDNVT--CWKGFVFLGFSSFG-ELQLL----LFVLFLS-LY
LVTITSNVF-IIIVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVMGGQ-AISFLGCATQMFF-SASWAC-TNCFLLSVMGFDRYV-AICA
PLHYASRMNPTLCAQLVGTSFLSGYLF----GLGMTLVIFRLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TRLSELGILILSLLVLLVSFFLISVSYAYILVAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VVIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVA-TPLL----NPIVYSLRNRAV---QSA---LR-------NAFRGSLLRKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MW-GANGS--TVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWSERALHT--PMYLFLCALSISEILYT--VA--------------
I-IPR---MLANLLSTQR-SITLLACASQMFF-SFTFGF-THSFLLTVMGYDRYA-AVCH
PLRYNVLMSPQGCACLVGWAWAGGSVM----GLVVTVAIFQLTFCGPNEIHH-FACHVPP
-LLKLACGDDVPVVAKGVGLVCITALLGCCLLILLSYALIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KSK---DWC------FSKSNISTSL-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FSIYLSFFHISENSTMKINQT--VLKEFILVGFSVYP-HAQTF----LFVVFFC-LY
LLTLTGNLT-IMSLTWVDRHLHT--PMYLFLGALSFSETCYT--LT--------------
I-IPR---MLADLLAKKR-SISVIGCALQMYF-FLGLGG-THCILLTLMGYDRFL-AICN
PLRYPLLMTNMACGKLVVSAWAAGFFI----SVTEIALIFRGSFCSPNLVEH-FFCHMRA
-IVRLSCLD-SELTEFIVTAISVSGLMGTFLLIILTYIFILSTVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-VIAVPYTVL-TPFL----SPLIFSLRNKDM---KNA---FRK------ALGKTHFLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MRN-YT--TVTSFLLWGFSSFP-ELQNL----LFIVILL-SH
VTILLANAL-IMAAIKLNKNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSENK-AISLPECATQMFF-FFGLGG-NNCFILSAMSYDRYT-AIHN
PLHYPILMTQKICFQLIMASGVLGFSV----SLCIVIIIFNLSFCNSNIIQH-FFCDIEP
PVVSLACNY-TFYQKMILLAFTAFVLVGSFILIMVSYVFIVTVVVKLPSAKGRYKT----
-----F--------------STCSAHFTV-VFIHYGFACFVYLRPKNS---DSFRDDT--
-LLAVTYTVL-TPLL----NPIIYSLRNKDM---QTA---LRK------DLGNVIKIFPK
MI-NKRSQKI---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MT-RQNQS--VITEFILIGFSNLG-HLQVP----LFFTFLL-VY
LTTLMANAT-IMTVIRLDRTLHT--PMYFFLFVLSFSETCYT--LV--------------
I-VPK---MLTNLLSMSQ-TISFSGCAAQLFF-FMGLAC-TNCFLIAAMGYDRYV-AICN
PLNYTLVVSRATCVLLVLASSCCGFLI----SVVVNVLVFSVPFCASNQINH-FFCDISP
-VIKLGCSD-TSLKEMVIFFLSILVLLVPFVLVFISYVFIVSAILKIASAEGQRKA----
-----F--------------ATCASHLTV-VVVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KSA---LSK------VLGRYSFPKTV
-------------------------------

----------------------MEGINETAVREFVFLGFSSLAELQ--PLLFVVFLLLYL
FTLGTNALI-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAHRKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVVMGHGVCGGLVGVACACGFTV
AQIITILVFHLPFHSSNQLHHFFCDISPVLKVASYHTRFSQIVIFMLCALVLVIPLSLIL
VSYIHIISAILH-FPSTLGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDALI
SVSYTILTPMFNPM-IYSLRNKEFKSALRRVVRRTIPL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------LV----LFVIFLC-LY
LIILSGNLT-IISVICLDHGLHT--PMYFFLGVLSTSETFYT--IV--------------
I-LPK---MLINLLSVLR-TVSFMSCAFQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYAILMSWRVCGQLAVTCILSGFLI----SLLGTTLVFSLPFCGSNKVNH-YFCDISP
-VIRLACAD-TYINELIIFIGGVLVLVVPLIFICISYGFIVSTVLKISSAEGKRKA----
-----F--------------STCASHLIV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--CVTEFLLLGFSSLG-ELQLV----LFVIFLC-LY
LIILSGNLT-IISVICLDHGLHT--PMYFFLGVLSTSETFYT--IV--------------
I-LPK---MLINLLSVLR-TVSFMSCAFQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYAILMSWRVCGQLAVTCILSGFLI----SLLGTTLVFSLPFCGSNKVNH-YFCDISP
-VIRLACAD-TYINELIIFIGGVLVLVVPLIFICISYGFIVSTVLKISSAEGKRKA----
-----F--------------STCASHLIV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

----------------------MEQINETLVREFVFLGFSSLAKLQ--QLLFVVFLLLYL
FTLGTNAII-ISTIMLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLTQKKTISFV
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICHPLRYSALMSQGVCGGLVAAACACGFTV
SLVTTSLVFQLPFHSSNQLHHFFCDISPVLKLASHHSRLSQIVIFLLGVFVLVIPLLLIL
VSYTQIISAILK-IPSTGGRHKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDSII
SVSYTILTPLFNPM-IYSLRNKEFKSALQRVMGQLLY-PVH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------VV-GQNYS--MVSEFILVGFSNFPPQLLPI----FFLLFLL-MY
LFTLLGNLL-IMATVRSECSLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLTDLLSTHR-TITFVACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AITH
PLTYNVLMSTRSCAHLVSWSWAGGSVM----GMMVTLIVFHLTFCGSNVIHH-FGCHALS
-LLNLACGKETTSVTLGVILVCVTVLMGCSFLIVLSYVFIVAAILKIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASIIYLKPKGPH---SMDSST--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RKNFT--EVSEFIFLGFSSFG-KHQIT----LFVVFLT-VY
ILTLVANII-IVTIICIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLLSLIFHNQ-PISLAGCATQMFF-FVILAT-NNCFLLTAMGYDRYV-AICR
PLRYTVIMSKGLCAQLVCGSFGIGLTM----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKT----
-----F--------------ATCVSHLTV-VIVHCGCASIAYLKPKSES---SIEKDL--
-VLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

----------------------MEWVNKTVVREFVFLGFSSLAGLQ--QLLFLVFLVVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTMLMGPGVCVGLVAAACACGFTV
AQIITTLIFHLPFYSSNQLHHFFCDISPVLKLASNHNHFSQIVIFMLCALVLIIPLLLIL
VSYIHIISAILQ-FPSTLGRCKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSVNQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALHRVVGRTISLPC--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--FVTEFLLLGFSSLG-ELQLV----LFVVFLS-LY
LIILSGNLT-IISAIHLDSSLHT--VMYFSLGVLSTSEIFYA--IV--------------
I-LPK---MLINLLSVLR-TLPFMRCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-ALCQ
ALHYPILMSWRVCGQLAATCIVSGFLI----SLVGTALVFSFPFYGSNKVSH-YFCDISS
-VIHLACAE-TYINELVIFICGVLVLVVPLIFICTSYGFIVHTIMKIPSVEGKQKA----
-----F--------------STCVSHLIV-VIVHYGCASFVYL-----------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RNNFT--EVTEFIFLGFSSFG-KHQIT----LFVVFLT-IY
ILTLAGNII-IVTITHIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFYNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICD
PLRYTIIMSKGMCALLVCGSLGTGLVM----AVLHVPAMFHLSFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTVNEIINYGVSSFVILVPIGLIFISYVLIVSSILKIVSAEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---LLQVYSLLFCIFLNVLAENVT--MVTEFLLLGFSSLG-DIQLV----LFVVFLF-LY
LAILSGNVT-IVSVIRLDKSLHT--PMYFFLGILSTSETCYT--FV--------------
I-LPK---MLVNLFSVAR-TISFNCCAIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYTILMSWRVCGQLAVTCIVSGFLI----SLLGTTLVFSLPFCCSNKINH-YFCDISP
-VIHLAYAG-SDINELIIFICGVLVLIVPLIFICISYGFIVSTILRIPSVEGKRKA----
-----F--------------STCASHLIV-VIIHYGCASFVYLRPSAKY-INISGKDR--
-LVTVNY-----------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------IEFVSLGFARSG-NHQIT--------------
-----------------------------------PFVTVYT--LV--------------
I-TPP---MLLGLTFHKQ-PISLAGCATQTFFIFVTLAT-NSCFLLTATGYDCYV-TICK
PLRDTVIMSKRMHASVVCGSFGTAL---------RLTAMFILPFCGKV-AGH--FCDIYP
-VRKLF-VG-TTINEMISYGVSSLVILVPIGLICNSCVLIISSILKIACTEGRKKA----
-----F--------------ATCASHLTV-VIVHSGCTLITYLKPKSET---SVEKSF--
--FSETYTII-TPLL----NPVVYHLRNKDV---KDD---LCR------AMGRNVS----
-------------------------------

----------------------MERINETTVREFVFLGFSSLAGLQ--LLLFVIFLLLYL
FTLGTNAII-ISTIVLDRSLHTPMYFFLSVLSCSETCYTFVIIPKMLVDLLARKKTISFL
GCAIQMFTFLFLGCSHSLLLAAMGYDRYVAICNPLRYTVLMGHRVCVGLVAAACACGFTV
AQIVTSLVFHLPFHSSNQLHHFFCDIFPVLKLASQQSRFSQIIIFMLCALILVIPLFLIL
VSYIHIISAILQ-FPSTLGRHKAFSTCASHLIVVIVHYGCASFIYLRPQSNYSSSQDVLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRVAERTISLPQH-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MVLNVYCCFFQISDIQTMKINQT--ILKEFILVGFSVYP-HVQTF----LFVVFFC-LY
LLTLAGNLI-IMGLTWVDRSLHT--PMYLFLSALSFSETCYT--LT--------------
I-VPK---MLEDLLAKDR-SISVTGCSLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNIVCGQLVASACTAGFFI----SLTETALIFRDSFCRPNLVKH-FFCHMLA
-VIRLSCID-SNHTEFIITLISVSGLLGTLLLIILTDVFIISTVLRIPSAEGKQKA----
-----F--------------TTCASHLTV-VIIHFGFASIVYLKPEAS-----G-DDT--
-LIAVPYTVI-TPFL----SPIIFSLRNKDM---KNA---FRR------MMGNTVALKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANLS--AVTEFILVGFSAFPHLQ-LV----FFLLFLL-MY
LFTLLGNLL-IMATIWGECSLHT--PMYLFLCALSVSEILYT--FA--------------
I-IPR---MLADLLSTHR-SIALTACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLVVTMAIFHLTFCGPNEVHH-FACHVPP
-LLKLACGNNVPDVTRGVGLVCIMALLGCCLLILLSYTFIVATILKIPSAEGRHKV----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---IKK------TFLSKLYPKNM
----T-LW-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-TANHT--EVREFVFQGFSNFQ-EHQLT----LFVVFLT-LY
MLTLAGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLSSLACLSQ-SISLEGCGTQLFF-FLGFAI-TNCLLLAVMGYDHYV-AICN
PLRYSIIMNWRVCAMLSSLVCATGFSL----SLVQAVAIFRLPFCDSL-IEH-FFCDVRP
-VLDVACAT-PIINDILTLIISLLAITVPATFLFISYILIISTILKIASTEGRKKT----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKPKSEN---TKDQNQ--
-LIAVTYTVI-TPLL----NPVVYSLRNKEV---QDS---LHR------VMGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANFS--SAAEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWREHSLHT--PMYLFLCALSISEILYT--FA--------------
V-IPR---MLADLLSTDH-SIALRACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLWYNVLMSPRGCACLVAWSWAGGSVI----GLVVTVAIFQLTFCGSNEIHH-FVCHVQA
-LLKLACGENVSILATGLGLVCITALLGCCLLILLSYAFIVATILRIPSAEGRHKA----
-----F--------------STCVSHLTV-VIEHYGFASVIYLKPKGPQ---SLEIDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MH--SMSEFILVGFSTFPRHLLPA----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCTLSTSEILYT--LA--------------
I-TPR---LLADLLSTRR-TITWAACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSVM----GLLVTTAVFHLTFCGPNEIHH-FFCHVPP
-VVKLACGTDVPVVAKGVGLVCIMALLGCCLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVVYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KTA---MTK------TFLRRLHPQSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------SQKE---VIQMQGFNRTS--VVTQFILVGFSNLE-ELQVL----LFVTFLL-LY
LTILMANAT-IMTVICFSRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSTIK-TISFIACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLVSLSTVTGFFI----ALVATNLICGMHFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNKEV---KTA---LKR------VLGIPVAT---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANFS--AVTEFILIGFSTFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATIWREHSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTDR-SISFTACASQMFF-SFMFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLVVTSAIFHLIFCGPNEVHH-FACHVPP
-LLKLACGTEVQVVAKGVGLVCITALLGCGLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KIA---MKK------TFLSKLYPEKI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LSMANSS--LVTEFLLMGFSSLG-ELQFV----LFVVFSS-LY
LIILSGNFT-IISVILLDRSLHT--PMYFFLCVLSISETLYT--IV--------------
I-LPK---MLINLLSVLR-TLSFMSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLQYPILMSWRVCGQLAVITIICGFLT----SLVGTVVVFSLPFCGPNKVDH-YFCDISP
-VIRLACAD-AHINELVIFIAGVFVLLVPLLFICISYGFIVHTILRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGCASSVYLRPSIKH-M--SGKDR--
-LVTVTYTII-TPLL----NPMIYSLRNKDV---QMA---IRK------VFGKIGFSSKT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----ILLHFRFGDHSRM-RENYT--LITEFILQGFSSFH-EHQIT----LFGVFLA-LY
VLTLAGNVI-IVSIIRVDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-LPR---MLSSLVGMSQ-SISLAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCAQLVWGACSIGLIV----AITQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCVD-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LFR------AVGGKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNLT--EVTEFIFLGFSVFG-KHQIT----LFVVFLT-IY
ILTLAGDIV-IVTIIRVDHHLRT--PMYFFLSMLASSEAAYT--LV--------------
I-VPR---MLFSLILHNQ-PISLEGCATPMFF-FVTLAV-NSGFLLTAMGYDRYV-AICS
PLRYTVVMSKGMCAGLVCGSFGTGLVM----AVLHVAAMFHLSFCGTV-VDH-FFCDIYP
-VMKLSCTD-STINEMISYGVSSSVILVPVGLNFITYILLVSTSLKIPSTRGRKKA----
-----F--------------ATCTSHLTV-VIVHYGCTSIIYRKPKSEN---SIEKDL--
--LSVTYTII-TPF-----------LRNREV---RDA---LRR------AVGKNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-LCNET--TWRNFVFLGFSSFG-NLQFL----LFAIFLF-LY
LITLTSNVF-IIIIIRLDSHLHT--PMYLFLSVLSFSETCYT--LG--------------
I-IPK---MLSNLAIGSQ-AISYVGCAVQMDF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMHPTLCTQLVGTSFFSGYLI----GMGMTLVIFRLPFCGSHEIHH-FFCDTPP
-VLSLASGD-TGLSELGILILSLLVLLVSFALITISYVNILVTIMRIPSAKGKQKA----
-----F--------------STCASHLTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QAA---FK-------NAFQGKLLGK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MRKTKGD-FR--TEY----SHLGSFM-NFSTR----IFIITLTPEL
DFQ-PANTC-IMAAIKLSHNLHT--PMYFFLCGLSFSETCTT--MV--------------
V-IPR---MLVDLLSHSK-TIPLPECATQMFF-FFWLAG-NNCFIMAAMSYDRYT-AIHN
PLHYALRMTPKVCFLLMLASWIVGFLV----SLNIAITIFSLHFCDSNIIQH-YFCDITP
-IVSLACDY-NSYHEATIFVLSAIVLVGSFILIMISYVFIGFTVMKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFAGFVYLKPQNN---DSFGEDM--
-LLAVTYTVL-TPLL----NPIVYSLRNREM---QIA---LRK------VVENANVYP-Q
IAKGEPEHLKSV-GIVDR-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-GLNYT--SLPDFILVGFSTFPQQLLPV----FFLLFLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTHR-SIAFLACAGQMFF-SFTFGF-THSLLLTVMGYDRYV-AICH
PLRYNVLMSPRGCVFLVAWSWAGGSAV----GLVVTTSIFCLNFCGSKEIQH-FLCHVPP
-LLKLVCGRHVPAVALGVGLVCITALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASIIYLKPKGPH---FQEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------KFLREFRSSDS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NHS--SVSEFILLGFSAFLQQLLPV----LFLLFLM-MY
LFTLLGNLL-IMATIWQQHILHT--PMYLFLCALFTSEILCT--FA--------------
I-IPR---VLANLLSTQH-YITLVACSGQMFF-TFTFGF-THSFLLNDLGYNRYV-AICH
PLCYSLLMSPCGCSC-----------L----GLVVTMDIFHFTSCGPNELHC-FACHMTP
-LLELACGNDVSSVSMLGF--VSSTILACFLLLLFSYTFIVVTFLRNLSAEGQRKA----
-----F--------------STFVSHLTV-VIVHYGFTSVIYLKPKGPN---SMDSNT--
-LMATTYTVF-TPFL----NLIIFSLRS-EL---MMA---MKK------TFLSKLFPQSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLCFRFGNQSMK-RENFT--LITDFVFQGFSSFH-EQQIT----LFGVFLA-LY
ILTLAGNII-IVTIIRMDLHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-LPR---MLSSLVGMSQ-PISLAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYMVIMNKRLRIQLVLGACSIGLIV----AITQVTSVFRLPFCARK-VPH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVEGRKKA----
-----F--------------ATCASHLTV-VIVHYSCASIAYLKPKSEN---TREHDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LERQ--N-QN--TITESNIIGFSKLG-HLQIF----LFFIFLL-GY
LTILMANAT-IMTVIHLNWALHT--SRYFFLFGLSCFEICYT--FV--------------
I--VK---MLT-KLSTSL-TICFSGYVSQLYF-SVGLAT--NCFLIAAMSYDCYV-AICN
PFNYTLI------------VSFCGFLI----SVVANVLVFSVPFSAS-NINH-FFCDISP
-VIKLGCTD-TNQKEMVIFFLNILVLLVPLVLIFISYVFIVSTILKISSVEGQHKV----
-----F--------------ATCVSHITV-VIFHYDFASFLYLRPTSL---FSSYKDQ--
-LVAVTYTVI-TPLF----NPLVCTLRNKE----VTA---LRK------VLSRYLFTK--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MSN-HT--TVSTFLLWGFSSFP-DLRGL----LFVMIFF-SH
GIILTANVS-IMVAVKLSHNLHT--PMYFFLCGLSFSETCST--MA--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFV-FFGLAA-NNCFIMAAMSYDRYT-AIHK
PLHYPILMTHKICFQFITASWMVGFLV----SLGIVIVVFNSSFCDSNTIQH-FFCDISP
-VVSLACDY-TSRHEMVIFGLSAFVLVGSCVFIVMSYVFIVSTVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKDR---DSFCEDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLGKTGSSLRG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PSVLHFRFSGHSME-RGNHT--LITEFVFQGFSSFR-EHQLG----LFVVFLA-LY
VVTLAGNAV-IVTIIRTDPHLHT--PMYFFLSMLSSSETVYT--LV--------------
I-LPR---MLSSLVGTNR-SISRAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRGCVQLVGGACGIGLIV----ATTQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCVD-TSVNETLTVIISVLVLVVPMGLVFISYVLIVSTVLKIPSARGRKKA----
-----F--------------ATCASHLTV-VVVHYGCASVAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------AAGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------LIFS---LIMMHGSNRTT--MVAQFILVGFSSLG-ELQLL----LFVVFLL-LY
LTILLANAT-IMAVIRCSRTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLAHLLSATK-SISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKRLGLGLVSLSGVTGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELVLFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPRSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLGMPVAIKVV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------LPEITL
HTLNNSNKNYFIRSKQTL-LENRS--MITEFVLLGFSNLG-DLQVL----LFFIFLL-VY
LTTLMANAT-IMTVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSTTQ-TISFSGCAAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTLVVSRATCVQLVLASSCCGFLI----SVVVNVLVFTVPFCASNQINH-FFCDISP
-VIKLGCTD-TNLKEMVIFFLSILVLLVPFVLIFISYVFIVSTILKIASAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LSK------VLSRYSSAKTV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------LLICFT-SKNHT--LVSEFTFQGFASFC-EHQFT----LFIMFFA-LY
MLTLAGNII-TVAIISLDHHLHT--PMYFFLSVLSASETVYT--LI--------------
I-IPK---MLCNLIGLSQ-SISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICH
PLRYTVIMNRRVCLQLVWGACSIGLIV----AATQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILVPMGLVFISYILIISTILKIASAEGRKKS----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SKDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEA---KDA---LLR------AIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-EGNHS--SVSEFILIGFSTFPRQLLPL----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEVLYT--LA--------------
I-IPR---MLADLLSTHH-SITFLACANQMCF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYSVLMSPRGCACLVAGSWACGSAV----GLVVTTAIFQLSFCGSHRIQH-FLCHVPP
-LLKLACGSNVPAVALGVGSVCISALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VVVHYGFASVVYLKPKGPR---FQEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KIA---LKK------TFLRRLHSNA-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNLT--EVTEFIFLGFSRFH-EHQIT----LFAVFLI-LY
TLTLAGNAI-IVTIIHIDCHLHM--PIYFFLSILASSETVYT--LV--------------
T-IPR---MLSSLIAQNQ-PISLAGCTTQVFF-FVTLAI-NNRFLLTVMGYDHHV-AICN
PLRYALIMSKRVCVQLMCGAFSTGLAM----AAVQVTSIFTLPFCHRV-VGH-FFCDILP
-VIKLSRID-TTVNEIINFVVSLSVILVPMGLVFISYVLFISTILNTASAEGQKKA----
-----F--------------AICASHLTM-VMVHYSCASTDYLKPKSEN---SVEQDLL-
--LSVTF-----------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENHT--MVNEFVFQGFSSFH-EYKFM----LFVVFLT-LY
LLTLAGNII-IVTIISIDRHLHT--PMYFFLSILSTSETVYT--LV--------------
I-VPR---MLTSLIGLSR-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTIIMNRRVCAQLVLGACSIGLLV----ALIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCVD-TTLHDIMNFIVSSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCTSHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVVYTVF-TPLL----NPVVYTLRNKEV---KDA---LHR------AIGRKLLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------PPSMANSS--RVTEFLLLGFSGFG-ELQPV----LFVLFLG-LY
LIILSGNFT-IISVIRLDRSLHT--PMYFFLCVLSTSEVFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFTSCATQMFF-FLGFAV-TNCLLLGVMGYDRYT-AICQ
PLRYPVLMSWRVCAQLAATCIVSGFLI----SLVGTTLVFSLPFCGSNRVNH-YFCDISP
-VIRLACAE-TYINELVIFICGVLVLVVPLIFICISYGFIVRTILKIPSADGKRKA----
-----F--------------STCASHLIV-VIVHYGCASSVYLRPSAKS-S--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QLA---IRK------VIGKTAVSLKT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLCFRFGNQSMK-TENFT--LITDFVFQGFSSFR-EQQIT----LFGVFLA-LY
ILTLAGTTV-IVTIIRIDHHLNT--PMNFFLSMQSTSETVYT--LV--------------
I-LPR---MLSSLVGMNQ-TISLAG----------------------SMGYDCYV-AICN
PLRYTVIMNRRVRIQLVLGACSIGLIV----AITQVTSVCRLLFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVV-------SLVLIISTILKIASVE----G-R-K
-K-A-F-A-------------TCASHLTV-VTVHY-------------------------
----SWASI------------ACLKPKNKEV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VFLMFNSGIASML-GQNHT--MVTEFILIGFSTFPQLQ-LM----FFVILLM-MY
LFTLLGNLL-IMLTIWNERSLHT--PMYFFLCALSISEIFYT--FA--------------
I-IPR---MLIDLVSTHH-NISFLACANQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMNPQGCAWLVASAWLGGIVM----GLVVTLAIFHLTFCGPNKIHH-FFCHVPP
-LVKLACGD-VSIVAMGVGMVCITALLGCFLLILLSYAFIVATVLRIPSAEGQHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKALE---SLEGDT--
-LMGITYTAL-TPFL----SPIIFSLRNKEL---KNA---LKK------VYLSKLCPLN-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----FLSFLDTTYDLME-GKNHT--LVSEFTFQGFSSFG-EHQLT----LFVVFLV-LY
TFTLAGNVV-IVTVISVDRRLHT--PMYFFLSTLSVSETVYT--LV--------------
I-IPK---MLCNLLGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICD
PLRYAVIMSKGICIQLVGGACSIGLIV----AMTQVLAVFRLPFCATR-VAH-FFCDIRP
-VMKLSCID-TTANEILTLIISVLVILVPMGLVFISYVLIISTILKIPSAQGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---SRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LLR------ATGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------SS-GQNYS--TVSEFNLIGFSNFPQQLLPT----FFLLYLL-MY
LFTLLGNLL-IMGTIWREHSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLADMLSTHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRDCARLVSWCWAGGSVM----GMMVTLIVFHLTFCRSNKIYH-FACHVLA
-LLKLACGKETASVTMGVILVCVTALMGCLLFIVLSYVFIVAAILRIPSTEGRHKT----
-----F--------------STCVSHLTI-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LLATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IQR------SFRRKFSSLNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VLAENFT--MVTEFLLLGFSSLG-EIQLP----LFVVFLF-LY
LVILSGNVT-IVSVIRLDQSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCAIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICR
PLHYPILMNWQVCVKLAAACGIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLVLVVPFFFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---LRK------MLGKKGSLLYD
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKINQT--VLKD--------LP-SCTDL----LFVIFFC-TY
LLTLSGNLA-ILGLTWVDRHLHT--LMYLFLSALSFSETCYT--LLSPKYWSGVSSPSPM
G-TPK---MLVNRLAKNI-NISVIGCGLQICF-FLGLGG-TNCMILIVMGHDRFL-AICS
PLRYLLLMTNMVCGKLVASAWVAGFFV----SVIETALIFRGSFCNPNLVKH--FCHMRA
-VVRLFCLD-SDLTEFIVTVISVSGLMGTFLVIILTYVFILSIVLKIPLAEGKQKA----
-----F--------------STCASHLTV-VIIHSGFASIVYLKPEAS-----GGDDT--
-VIAVPYTVV-TPFL----SPLIFSLRNKDM---KNA---FRM------VLGKIFLEYSC
IITA---------------------------

----------------------MEWVNETMVREFVFLGFSSLARLQEQELLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLSILSCSETCYTFVIIPKMLVDLLARRKTISFL
GCAIQMFTFIFLGCSHSLLLAAMGYDRYVAICNPLRYTVLMGHRICVGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDIFPVLKLASQQSYFSQIVIFILCALILVIPLLLIL
VSYIHIISAILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSNYSSSQDVLI
SVSYTILTPLFNPM-IYSLRNKEFKSALCRVMERTIPLPQP-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANRS--GVTEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SITFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGENVLVVARGVGMVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MINQT--ILKEFILIGFSAYP-LVQTA----LFVVFLC-LY
MVTLAGNLA-IMGLTWVDRSLHT--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLIDKDN-RISVTGCGLQMCF-FLGLGG-TNCILLTLMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFVVTLMSVSGLLGTFLLILLTYVFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VLIHFGFASVVYMKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDM---KNA---FRK------IMRKTVVMKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------GFSAFPQ-LQPA----FFSLFLL-MY
LCTLLGNLL-ITATVRSERGLHT--PMYLFLCALSVSEVLYT--VA--------------
I-TPR---MLADLLAARH-AISLRACASQMFF-SFTFGF-THSFLLTAMGYDRYV-AICH
PLRYPVLMGARGCARLVAWSWAGGCVM----GLVVTASIFHLTFCGPSRIHH-FACHVPP
-LVKLACGRDVPAVALGVGAVCITALLGCLLLILLSYACIVAALLKIPSAEGRRKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPRGPR---SPEGDT--
-LTGFTYTVL-TPFL----SPIIFSLRNKEL---KAA---MKK------VFVKRF-----
-------------------------------

----------------------MEWVNETLVREFVFLGFSSLAGLQ--QLLFAVFLLVYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCFETCYTFIIVPKMLVDLLVQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTVLMGYGMCLGLVAAACACGFTV
SLVTTSLVFHLPFHSSNRLHHFFCDISPVLKLASHHSRLSQLVIFMLGVFALIIPLLLIL
VSYIRIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRAMVQTSY-PVN-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVTWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGENVLEVAKGVGIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------IFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--TPSLRPHFRFSGHSTE-RENCT--LITELVFQGFSSFC-EHQLT----LFVVFLA-LY
AFTLAGNVV-IVTIISVDRHLHM--PMYFFLSMLSASETTYT--LV--------------
I-IPK---MLCNLLGLSR-PISLAGCATQMFF-FLTLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVLMNKTVCIQLVGGACSIGLIV----ATTQVLAVFRLPFCATK-VAH-FFCDIRP
-VMKLSCVD-TTANEILTVVISVLVILVPMGLVFISYILIISTILKIPSAQGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASVAYLKPKSEN---SRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KNA---LLR------ATGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------TMQINQT--IVKEFTLIGFSLYP-DAQIL----LFVVFFC-LY
LLTLRGNLT-IMGLTWVDRALHT--PMYIFLSALSFSETCYT--LS--------------
I-IPK---MLADLLAKKR-SVLVLGCGIQMYF-FLGLGG-TNCAILTLMGYDRFL-AICN
PLRYPLLMTHVLCGELVASAWAGGFFV----SLIETALIFRDFFCSPNLVKH-FFCHMRA
-VVRLSCLD-SNLTEFIVTLISVSGLLGTFLLIILSYVFILSTILQIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEGS-----RRDDT--
-LIAVPYTVI-TPFL----SPLIFSLRNKDM---KNA---FVK------VVGKILKYREH
L------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-QLNFT--VVTEFTFEGFSIFGWHHRLI----LFVVFLA-LY
LLTLASNAI-ILTVIHLNHHLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPR---MLSCLLSPQQ-AISIPGCATQLFF-YLTFGV-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGRKACIHLASGSWSIGLTI----AVTQVSSVFSLPFCDANVISH-FFCDIRP
-LMKLACAD-TTVKEFITLLISLCVLVLPMVLIFISYVFIVTTILKIASAEGRRKA----
-----F--------------TTCASHLTV-VIVHYGCTSFIYLKPKSKN---SL-QDR--
-LISMTYTVI-TPLL----NPVVYSLRNKEV---KNA---LLR------TLGRKPLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LL-----LLFRLF-SKNYT--LVSEFIFQGFSSFH-EHQLT----LFVVFLA-LY
LFTLAGNII-IVTIIGLDRHLHT--PMYFFLSMLSVSETVYT--LV--------------
I-IPR---MLFDLLGLSR-PISWAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMSRRLCIQLVWGACSIGLTV----AMTQVSAVFRLPFCTTK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLVISVLVILIPMGLVFISYILIISTILRMASAEGRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KNA---LCR------AIGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MCDLMK-KENHS--LVSVFIFQGFSSFH-EHKLT----LFVVFLT-LY
IFTLAGNVI-IVSIISIDHHLHT--PMYFFLSMLSGSETVYT--LV--------------
I-IPR---MLFNLIGLSQ-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMSKRVCMQLVWGACSIGLIV----AMTQVSAVFRLPFCTTK-VPH-FFCDIRP
-VMKLSCID-TTVNEILTMIISVLVILIPMGLVFISYILIISTILKIASAEGRRKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSDN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KGA---LCR------AIGKKL-----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LEKREIN-AS--EVSKYLGRLYVIYI-DFHTR-----IILLTLITE
LDFSTANVS-IMVAIKLTRHLHT--PMYFFLCGLAFSETCTT--VV--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFF-FFGLGG-NNCFIMAAMSYDRYT-AIHN
PLHYPVLMTRKICFQLMTASCVTGIVV----SLCIALIVFNLSFCDSNIIQH-FFCDILP
-VVCLACDY-TPYHEMAIFMLSAFVLVGSFILIMISYVFIGSIVIKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCMHYGFAGFIYLRPKDS---DSFREDM--
-LRAVTYTVL-TPLL----NPIVYSLRNKEM---QIA---LRK------VLDSTHRFIPQ
MVKKDPEHKLQI-AGK---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNYT--FVSEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMTTIWSEHSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLADLLSTLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FFCHVPP
-LLKLACGENVLEVAKGVGIVCITALLGCFLLILLSYAFIVVTILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNS---MKK------IFLSKLYPE--
----------KI-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------KQQENATW--LVTEFLLVGFSNLP-DLRTT----LFALFFL-TY
LVTLSGNVT-IITVIHADRTLHT--PMYRFLAALSLSETCYT--LV--------------
T-IPN---MLARLWMENQ-AISISGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLCLGALVFCSGFSV----ASIETSLIFSSRFCRSNRVEH-FFCDIAP
-VLKLSCAE-SASKALAIFFLSILVVLISFLLILLSYAFIVAALLRIPSAAGRSKA----
-----F--------------STCAAHLTV-VIVHFGCASIIYLRPESGG-N--PDQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RLA---LRR------ILARSHLFHEH
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILFGFSAFPHQMLPA----LFLLYLL-MY
LFTLLGNLV-IMAAIWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLSDMLSTHR-SITFIACANQLFF-SFTFGY-THSFLLVVMGYDRYV-AICR
PLHYHALMSLQGCARLVAWSWAGGSLI----GMSLTIIIFHLTFCESNVIHH-ILCHVFS
-LLKLACGERTAFVTIAVILVCVTPLIGCLVFIILSYIFIVAAILRIPSTEGRHKT----
-----F--------------STCASHLTV-VIVHYGFASIIYLKSRGLY---SQYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---IIK------SFHRNVCQQSI
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILSGFSACPQQLLPI----LFLLYLL-MF
LFTLLGNLL-IMATVWIERRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLFTHR-SITFVACAIQMFF-SFMFGF-THSFLLMVMSYDRYV-AICY
PLRYNMLISPRGCAHLVAWTWAGGSVM----GMMVAMIVFHLTFCGSNVIHH-FLCHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIVPAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVMHYSFASLIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFCRRFCPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--YVTEFLLLGFSSLG-ELQLL----LFAVFLC-LY
LIILSGNFT-IISVIRLDRSLHT--PMYFFLCVLSTSEIFYT--IV--------------
I-LPK---MLINLLSVLR-TLSFVSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRMCGRLAVTCIVCGFLI----SLVGTTLVFSLPFCGSNKVNH-YFCDISP
-VIRLACAD-TYINELIIFICGVLVLVVPLTFICISYGFIVSTILKIPSTEGKHKA----
-----F--------------STCASHLIV-VVVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNHS--MITEFILIGFSNLG-DMQIL----LFFIFLL-VY
LTTVMANVT-ITTVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLINLLSPVP-AISFSGCAAQLYF-FVGFAC-TNCFLIAVMGYDRYV-AICN
PLNYTLILVLASSFDF---------QI----SVAANVAAS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKINQT--VQEEFILVGFSVYP-HAQTF----LFVVFFF-LY
LLTLTGNLA-IMSLTWVDRHLHT--PMYLFFSALSFSEICYA--LT--------------
I-IPK---I----------------------S-FLGLAG-TNCFILTLMGYDRFL-AICN
PLRYPLLMSNMACGKPVA----AGFFI----SVTEPGMIFRGSFCSPNLVKH-FFCHMRA
-VVRLSCLD-SELTEFIVTAISVSGLIGTFLLIILIYVFIVTTQ---------AEV----
-----L--------------STCASHLTV-VIIHFGFASI--------------GEMT--
-HSAIPYTVI-TPFF----SPLIFSLRNKDM---KNV---FRK------ALGKTNSLNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----NTHLLFLSISDIQTMWINQT--ILKEFILVGFSVYP-DIQVL----IFVVFFC-LY
LLTFMGNIA-IMSLTWVDRALHI--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLADLLAKKR-SISVVGCALQMCF-FLGLGG-TNCIILTLMGYDRFL-AICS
PLRYPLLMTNMACGQLLASAWAGGFFI----SLIETSLIFRGFFCSPNLVKH-FFCHMQA
-VVKLSCQD-SDFTEFIVTVISVSGLLGTFLLIILTYIFILSTIFSIPSVEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAIPYTVI-TPFL----SPLIFSLRNKDM---KTA---FKK------VLGKIVALDK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MNYS--MVTEFILVGFSNFPQHLLPT----FFLLYLL-MY
LFTLLGNLL-IMTTVWSERSLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSTRR-TITWAACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSNRSCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNVIHH-FLCHVFS
-LLKLACGNENSSVTLGVILVCVSALMGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYSFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANIS--AVTEFILIGFSSFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSTNR-SISYTACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLLVTSAVFHLPFCSSNVIHH-FFCHVPP
-LMKLACGDNVSTVAKGVGLVCIAALLGCGLLILLSYAFIVAAILRIPSPEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLERDT--
-LMGITYTAL-TPFL----SPIIFSLRNKEL---KEA---VKK------TFLSKLFLHRS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NHS--ATSGFIL-IFSTFLQKLLPA----FFLLFLL-MY
LFMLLGNLI-ILATVRSERSLHT--PKYLPLCALSTSEILYT--MA--------------
I-IPC---MLY--------SIAFLACASQM-F-SFIFGF-THSFLLTVMGYDCYV-AIL-
--------------------------V----GLVVTMAFFQLTFCGPYEIQH-FLCHVPP
-LLKLACGSNVPVVALGMGSVCITALLSCFLLILLPYVLIMATILKFPSPEGWCKA----
-----F--------------ATFASHLIV-VI------------PKGPH---SQEGDT--
-LMAATYTVF-TPFL----SPIIFSLRNKEL---KVA---MKK------TFFNKLYSSGT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----LFISFSTEGHLMK-AKNHS--EVSEFVFQGFSNFQ-ELQVI----LFVVFLT-LY
ILTLAGNVI-IVVIIRIDRHLHT--PMYLFLSILSTSETFYS--LV--------------
I-IPR---MLSSLVGLSQ-SISFMGCATQMFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSAIMNWKVCALMASSVAITGFSL----SLVQAVAIFRLPFCDPL-IEH-FFCDVRP
-VLDLACVN-TFINDILTLIISLLAITAPATFLFVSYILIISTILQIASAAGRQKA----
-----F--------------ATCASHLTM-VIIHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LKR------ALGRKPL----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------TMKINQT--FLEEFIFLGFSAYL-EWQIV----LFVCFFF-VY
LLTLTGNLV-IMALTWVDHVLHI--PMYIFLAALSFSETCYT--LA--------------
I-IPK---MLVDLLANNR-PISIPGCGLQMFF-FLGLGG-TNCIILTVMGLDRFL-AICH
PLRYSTLMTNKACGQLVALAWIDGFFV----SLTEAMLIFWGPFCGPNLI-N-FFCHMRA
-VVKLSCLN-SDIRDLAVIVIPVSGLLRTFLFIILTYVFILSTVLKIPSAEGRKKA----
-----F--------------STCASHLTV-VIIHFGFAAIVYLKPEAQ-----EGDDA--
-LMTIPYTVV-TSFL----SPNIFTLRNKDM---KNS---LKR------VLDNKDYNEGL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLCFRFGNQSMK-RENFT--LITDFVFQGFSSFH-EQQIT----LFGVFLA-LY
ILTLAGNII-IVTIIRIDLHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-LPR---MLSSLVGMSQ-PISLAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYMVIMNKRLRIQLVLGACSIGLIV----AITQVSSVFRLPFCARK-VPH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIIPTILKIASVEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSED---TREHDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------N-HT--TVSTFLLWGFSGFP-DLQNF----LFVMIFF-CH
VTTVTANVS-IMVAIQLSHNLHT--PMYFFLCGLSISETCTT--MV--------------
I-LPR---ILVDLLSDNK-TISLPECATQMFF-FLGLGG-NNCFIIAAMSYDRYT-AIHN
PLHYAIRMTHKMCLQLMMASWMVGFLV----SLCIVITVFNLSFCDSNTIQH-FFCDISP
-VVSLACDY-TLYHEMATFLLSAFVLVGSFILIMISYVFIGSTVLKMPSAKGKYKA----
-----F--------------STCSSHLTV-VCIHYGFACFVYLRPKDS---DSFHEDM--
-PMALTYTVL-TPLL----NPIVYSLRNKEM---QIA---LMK------VVDNA------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQRINQTI--RVTKFILVGFSSLG-ELQML----LFVIFLF-LY
MTILLANAT-IMTVIRCSRSLHT--PMYGFLFILSFSETCYT--FV--------------
I-IPQ---LLDHLLSDTK-TISFVACATQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICF
PLRYMVIMNKRLGLGLISVSAATGFFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELVLFSLSILVIMVPFVLILISYGFIVNTILKIPSADGKRKA----
-----F--------------ATCVSHLTV-VIVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KAA---LKR------VFWRPAPSKLV
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RNNFT--EVIEFVFLGFSSFG-KHQIT----LFVVFLT-IY
ILTLAGNII-IVTITHIDHHLHT--PMYFFLSMLASSETVYT--LV--------------
I-VPR---MLSSLIFYNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICN
PLRYTIIMSKGMCALLVCGSLGTGLVM----AVLHVPAMFHLPFCGTV-VEH-FFCDIYP
-VMKLSCVD-TTVNEIINYGVSSFVILVPIGLIFISYVLIVSSILKIVSTEGQKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNTS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MQINQT--IVKEFTLIGFSLYP-DAQIL----LFVVFFC-LY
LLTLMGNLT-IMSLTWVDRALHT--PMYIFLSALSFSETCYT--LS--------------
I-IPK---MLADLLAKNR-NISVIGCGLQMYF-FLGLGG-TNCIILTVMGYDRFL-AICN
PLRYPLLMTHILCGELVASAWAGGFFV----SLIETALIFRDFFCSPNLVKH-FFCHMRA
-VVRLSCLD-SNLTEFVVTLISVLGLLGTFLFITLTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCVSHLTV-VIIHFGFASIVYLKPEGS-----WGDDT--
-LIAVPYTVI-TPFL----GPLIFSLRNKDM---KNA---FRK------VVGKIVRLKY-
-------------------------------

----------------------------------VFLGFSSLASLQ--QLLFVVFLLFYL
FTLGTNAII-ISTIVLDRALHTPMYFSLAILSCCETCYTFVIVPKMLVDLL---------
-----MFTFLFPGCSHSFLLEAM------AICNPLHYTVLMRYRVCVGLVVATCACGFTV
AQIITFLVFHLPFHSSNELHH-FCDISPVLMLASHHTHFSQIIIFILCTLVLVTPLSLIV
VSYVHIISAILQ-FPSTLGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSS------
-MSYTILTLLFNPV-IYSLRNKEFKSALHRVVGRTISL----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-QKNVT--CWRGFVFLGFSSFG-ELQLL----LFALFLS-LY
VITLTSNIF-IIVVIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-VPR---MLFGLAMGSQ-TISYAGCAAQMFF-SASWAC-TNCFLLAVMGFDRYV-AICA
PLHYASRMNSTFCSQLVFASFLSGYLF----GLGMTLVIFHLSFCSSHKIQH-FFCDTPP
-VLSLACGD-TALSELGILILSLVVLLVSFISITISYMCILVAILRIPSADGRKKA----
-----F--------------STCASHFTV-VIFHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTT---MK-------NAFQGSLLGKR
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-TTNHT--EVTEFVFQGFSNFG-EHQLT----LFAVFLA-LY
IPTLAGNVI-IVTIIHIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLSSLIGLSQ-SISLVGCGTQLFF-FLGFAI-TNCLLLAVMGFDRYV-AICN
PLRYSIIMNWRVCTILASSVCASGFLL----SLVQAVAIFRLPFCNSL-IEH-FFCDVRP
-VLDLACAT-PVINDILTLVISLLAITAPATFLFVSYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRR------VVGRKSLP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANFT--GVREFVFQGFSNFQ-EYQFI----LFVVFLA-LY
ILTLAGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFGI-NNCLLLAVMGYDRYV-AICN
PLRYSIVMNWRVCVILASSICATGFFL----SLVQVMSIFRLPFCHSL-IEH-FFCDVRP
-VLNLACAV-PVINDILTLALTLLVITAPATFLFISYVLIISTILKIASADGWKKT----
-----F--------------ATCSSHLTV-VVIHYGCASIVYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------KFNQT--VLKEFILVGFSAYP-NVQAF----LFVIFFC-LY
LFTLAGNLT-IMGLTWGDRFLHT--PMYLFLSALSFSETCYT--LA--------------
I-IPK---MLADLLSKSR-AISVTGCGLQMCF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNVACAQLVASAWAGGFLV----SLIETVLIFRGSFCSPNLIRH-FFCHMRA
-VVRLTCRD-SDLTEFIVTVISVSGLLGTFLLLLLTYVFILSTVLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIVHFGFASIVYLKPEAS-----GGDDT--
-LMAVPYTVI-TPFL----SPIIFSLRNKDM---KQA---FRK------VMRKTDALKKY
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-RPNFT--AVAEFTFEGFSIFGWQPRLI----LFVVFLV-LY
LLTLASNAI-ILTVICLNHQLHT--PMYFFLSVLSISETCYT--VA--------------
I-IPR---MLFSLLSPQH-AISIPDCATQLFF-YLTFGV-NNCFLLTAMGYDRYV-AICN
PLRYSVIMGKKTCIQLAGGSWSIGLST----ATIQVSSVFSLPFCDASVISH-FFCDIRP
-LMKLACAD-ITIKELTTLLISLCVLVLPMVLIFISYVLIVCTILKMASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------ALGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGN-HS--TVTTFLLWGFSSFP-ELHNL----LFVVILL-SH
VTILLANAS-IMVAIKLNHNLHT--PMYFFLFALSFSETCTT--MV--------------
I-LPR---MLVDLLSESK-AISLPECATQMFF-FFGLAA-NNCFIMAAMSYDRYT-AIHS
PLHYHIFMTPKVCSQLVIASCVVGFLC----SLSITFTIFNLSFCDSKTIQH-FFCDISP
-LVHLACDY-TAHHAMIIFMVSAFVLVGSFVLIMISYAFIVFLVVKMPSVQGRHKA----
-----F--------------STCSSHLTV-VSMHYGFACFVYLIPKNS---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QTA---LRK------VLSSINKMLPC
LAIKKPEHLRTT-IEH---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KSNAT--FVTEFLFEGFSSFNWQHRLS----LFAVFLT-LY
FLTLSGNVI-IVTIIHLDHHLHT--PMYFFLAILSISDTCYT--VT--------------
I-IPR---MLSDLLNPYH-TIAFQDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGRAACVRLASGSLGIGLGM----AIVQVTSVFSLPFCDGFVIPH-FFCDVRP
-LLKLACTD-TTINEIINFVVSVCVLILPMGVVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYLKPKSQS---LLGQDR--
-LISVTYTLI-TPLL----NPLVYTLRNKEV---KDA---LYR------AIWKKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--SWRDFVFLGFSSSG-KLQHL----LFALFLS-LY
LITLTSNVF-IIIAIRLDSHLHT--PMYLFLVFLSFSETCYT--LG--------------
I-IPR---MLFGLAMGDQ-AISYVGCAAQMFF-SASWAC-TNCFLLAAMGFDRYV-AICA
PLHYASLMNPTLCAQLVVTSFLIGYLF----GLGMTLVIFHLSFCSSHEIHH-FFCDTPP
-VLSLACGD-TGLSELGILILSLLVLLVSFFFITISYAYILAAILKIPSTEGQKKA----
-----F--------------SICASHLTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAMTYTVV-TPLL----NPIVYSLRNRAV---QTA---LR-------NAFRGRLLIIK
NFLI---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------FIQWDQLSMANSS--CVTEFFLLGFSSLG-ELQLI----LFVVFLC-LY
LIILSGNIT-IISVIYLDHSLHT--PMYFFLCVLSTSETFYT--IV--------------
I-LPK---MLINLLSVFR-TMSFVSCASQMYF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPILMSWRVCGQLAVTCIVSGFLI----SLLGTTLVFSLPFCGSNKVNH-YFCDISP
-VIRLAYAE-TYINELVIFIGGVLVLVVPLIFIFISYGFIASAILKISSAEGKQKA----
-----F--------------STCASHLIV-VVVHYGCASFVYLRPSAKY-T--SGKDR--
-LVTVTYTII-TPLL----NPVVYSLRNKDV---QLA---IRK------MIEKTRLRFFN
YVK----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KPNST--AVTEFLFEGFSSFGWQPRLV----FFVVFLI-LY
LLTLSGNVI-IVTIIRLDHHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPH---MLYGLLNPYQ-PIAIQGCATQLFF-YLTFGI-NNCFLLTAMGFDRYV-AICK
PLQYSMIMGKEACVQLASGSLGIGLCM----AIVQVTSVFGLPFCDDFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMGLVFISYVLIISTILKIASTEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYTVI-TPLL----NPLVYSLRNKEV---KDA---LYK------AMGQKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------M--KRVKFVFQGFSSFQ-EHQLI----LFVVFLT-LY
ILTLTF----------------------------------YS--LV--------------
I-IPG---MRSSLL----------------FF-FLGFAI-TNCLLLAVMGYDHYV-AICN
PLGYSVVMNWKVCAILASSACATGFSL----SLVQTVAIFRLPFCSPL-IEH-FFCDIWP
-VLDLACAT-PVTNDILTLIISLLAITAPATFLFNSYVLIISTILKIASAGGQKKT----
-----F--------------ATCASHLTV-VIIHYGGASIAYFKPKLEN---TKDQDQ--
-LISVTHTVI-TPLL----NSVVYSLRNKEV---QDA---LQR------VLRRKFFP---
-------------------------------

----------------------MEWVNETWVREFVFLGFSAL----------MVFLLLYL
FTLGTNAII-MSTIVLDRALHTPMYFFLSVLSCSETSYTFVIMPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYGRYVAICNPLRYTVLMGHRVCLGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSRLSQLVIFMLGVLVLVIPLLFIL
VSYVRIISAILK-IPSSVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRTMSKTWF-PLS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GPNYT--SVSEFIFIGFSNFPRQLMPV----FFVVILL-MY
LFTLLGNLL-IMATIWSDRNLHT--PMYLFLCALSISEILYT--LS--------------
F-IPR---MLADLLSTHH-SITFLACANQMFF-SFMFGF-THSLLLTVMGYDRYV-AICH
PLHYNVLMSPRGCAFLVAGSWAGGSAV----GLVVTTSIFHLPFCGPNQIQH-FLCHVPP
-MLKLACGSDVPPVALGVGLICITALLGCFLLILLSYTFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGPH---FEEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLRKFCSSNT
-------------------------------

----------------------MECVNKTVVKEFVFLGFSTLAELQ--LLLFIVFLLLYL
FTLSTNAVI-ISTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLARKKSISFL
GCAVQMFAFLFLGCSHSFLLAAMGYDRYVAICHPLRYTVLMGHRVCVGLVAAACVCGFTV
AQIITSLVFHLPFQTSNQLRHFFCDISPVLKLACHHAHFTQITIFLLCVLVLVIPLLLIL
ASYVHIISAILQ-FPSTLGRYKAFSTCASHLIVVIVHYGCASFIYLRPKSGYSSSQDALI
SVSYTILTPLFNPV-IYSLRNKEFKSALHRVIGRTVTLRQC-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VPGMKLGNETW--IVKEFVLVGFSNFP-DLKPT----LFSLFLL-MY
LITLSGNIT-IITIIYLDHTLHT--PMYCFLGVLSLSETCYT--LV--------------
T-IPN---MLVHLLMENQ-VISISSCRAQMFF-FLGLGC-SNCFLLTLMGYDRYV-AICH
PLRYPMIMSPSVCIRLGALVFCSGFLV----AIIETCLIFSSSFCNDNRVVH-FFCDIAP
-VLKLSCTQ-SIAKALAIFFLSVIVVLFSFLLILLSYAFIVAAILRIPSAEGRRKA----
-----F--------------STCVSHLTV-VIVHFGCASIIYLRPESGS-N--PEKDL--
-MVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LKR------TLGRRLRTQS-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------AA-GQNYS--MVSEFILVGFSTFPQHLLPA----FFLLFLL-MY
LFTLLGNLI-IMATVWSERGLHT--PMYLFLCALSTSEILFT--VA--------------
V-TPR---MLVDMLSSHR-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSTRTCARLVSWTWAGGSVM----GMMVTLIVFHLTFCGSNVIHH-FGCHALS
-LLKLSCGMGTSSVTLGVVLVCVTALTGCLFLIVLSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---IKK------SFQRKFSPLSS
-------------------------------

----------------------MSRVNHTTMSEFILLGFSHLGGSQ--RLLFGLFLPIYL
VTLEANAVI-VTTIVLDRRLHVPMYFFLATLSCSETLYTLVIIPKALVDLLAQHRAITIT
ACAFQMGSFLFLGCSHSFLLAAMGFDRYVAICRPLNYARLMTRGVCMVLVAAASSCGSAV
SLVVTFLIFGPPGPSSDRLQHFFCDIPPVLKATLPPGSPRRGVILALGALVLVIPLSLIA
ASYAHIVATILR-IPSSRGRVKPFSTCASHLIVVTIHYTCASFIYLRPGAGDSSGRDALV
SVTYTAVTPLLNPV-IYSLRNRDFKAALNRVFERIFCPARL-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------PGMKLGNETW--IVKEFVLVGFSNFP-DLKPT----LFSLFLL-MY
LITLSGNIT-IITIIYLDHTLHT--PMYCFLGVLSLSETCYT--LV--------------
T-IPN---MLVHLLMENQ-VISISSCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYPMIMNPSVCIRLGALVFCSGFLG----GHHETALIFSSSFCNDNRVVH-FFCDIAP
-VLKLSCTQ-SIAKALAIFFLSVIVVLVSFLLILLSYAFIVAAILRIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHFGCASIIYLRPESGS-N--PEKDR--
-MVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LKR------TLGRRLRTQSL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNHS--VITEFILIGFSNLG-DLQIF----LFFIFLL-VY
LTTLTANAT-IMSVIRLDRALHT--PMYFFLFILSCSETCYT--LV--------------
I-VPK---MLTNLLSTIP-SISFSGCVAQLYF-FVGLAC-TNCFLIAVMGYDRYV-AICN
PLNYTIIVSKATCIQLVLASGLCGFLI----SVVVNILVFSVPFCASNRINH-FFCDISP
-VIKLGCTD-TNLKEMAIFFLSILVLLVPFVLIFISYVFIVSTILKISSAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCASFIYLRPTSLY-S--SDNDL--
-LVAVTYTVI-TPLL----NPLVYTLRNKEV---KTA---LRK------VLSRYSFPKM-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MVAIKLSHNLHT--PMYFFSLACPF------------------------
---QK---PLVDLLSKSK-TISLPECATQMVF-FFGLAA-NNCFIIAAMSYNRYT-AIHN
PLHYTVLM-------LLMASWVVGFLI----SLCITIIIFNLSFCDSNNIQH-FFCDISP
-VVHLACDY-TSHEAMAIFVLSAFVLVGSFILIMISYVFIVSLVVKMPSAKGRYKA----
-----F--------------STCSSHLTV-VSIHYGFACFVYLRPKNS---DSFHEDM--
-LMAVTSTVL-TPLL----NPIVYSLRNKEM---QIA---LKK------VEGSIIKFFSY
LTNKKKS------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RTNFT--GVREFVFQGFSNYQ-EFQLT----LFVVFFA-LY
LLTLAGNVI-IVTIIRIDQHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYTIIMNWRVCVILASSVCATGFLF----SLVQAVSIFRLPFCNSL-IEH-FFCDVRP
-VLDLACEV-PVVNDILTLVLSLLAITAPATFLFVSYVLIISTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VVIHYGCASIAYFKPKSEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VMGRKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSKVILAENVT--MVTEFLLLGFSSLG-EIQLA----LFVVFLF-LY
LAILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGLMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKA----
-----F--------------STCASHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPVVYSLRNKDV---QLA---IRK------VLGKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TTSEFILFGFSAFPHQLLPA----LFLLYLL-MY
LFTLLGNLL-IMATVWTERQLHT--PMYLFLCALSISEILFT--IA--------------
I-TPR---MLGDLLSTHH-SITFVACAMQTFF-CFMFGY-AHSFLLMVMGYDCSV-AICH
PLCYNVFMSPTVCAHLVTWSWAGGSVM----GMIMTSIVFHLTFCESHVIHY-IFFHVFS
-LLKLACGDEMGSVTIGVILVCVIPLIGCLSLIILSYVFIVSAILRIPSPEGRHEI----
-----F--------------STCVSHLTI-VIVHYSFASMIYLKPKGPH---SIYTNT--
-LMSTIYTVF-TPFL----SPIIFSLRNKEL---KNS---INK------NYHRKLCLQNP
-------------------------------

----------------------MGQVNETAVTEFIFLGFSSLAGLQ--RLLFLVFLLLYL
FTLSTNAII-ISTIVLDRALHTPMYFFLAILSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAVQMFTFLFLGCSHSFLLAVMGYDRYVAICNPLRYTVIMGPGVCGGLVASACACGFTV
AQVITSLVFRLPFHSSNELHHFFCDISPVLKLASHHTRLSQIVIFLLCALVLVIPLLLIL
VSYIHIISAVLQ-FSSTGGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSGYSSSQDALI
SVSYTILTPLFNPM-IYTLRNKEFKSALHRVVGRKFFLPQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSAFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRVHT--PMYLFLCALSVSEILFT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCASQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLHYNVLMSPRDCACLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FACHVLS
-LLKLACGNKTSSVIMGVMLVCVTALIGCLFLIILSYVFIVAAILRITSPEGRHKT----
-----F--------------STCVSHLTV-VVVHYRFASLIYLKPKGLH---SMYSDT--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFYRKFCLLSS
C---VPIWW----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVAEFIFLGFSIFG-NHQIT----LFVVFLS-TY
IFTLTGNII-VITVICIDRHLHT--PMYFFLSMLSSSETVYT--LV--------------
I-IPR---MLSGLIFYNQ-PISLGSCATQMFF-FAILAA-NNCFLLTVMSYDRYV-AICK
PLRYTVLMNKGVCARLVCGSFGTGLVM----AVLHVTAMFNLPFCGTV-VEH-FFCGIYP
-VMKLSCID-TTVNEIISYGVSSFVIIVPVVLVFRSYILIISSILKIPSVEGRKKT----
-----F--------------ATCASHLTV-VVVHYGCAAIAYLKPKSEN---AIEEDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LHR------AVGRNSS----
-------------------------------

----------------------MEWANETLVTEFVFLGFSSLAGLQ--RLLFAVFLLVYL
FMLGTNAII-VSTIVLDRALHTPMYFFLGVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTVLMGHGVCVGLVAAACACGFTV
AQIITSLVFHLPFHSSNQLHHFFCDIFPVLKLASHHSYLSQLVVFVLGVFALIIPLLLIL
VSYIHIISAILK-IPSSVGRYKTFSTCASHLIVITVHYGCASFIYLRPKSNYSTSQDTLI
SVFYTILTPLFNPM-IYSLRNKEFKSALQRTMAQTSCLVN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

--------------LSFLQVLSMERGNGTLVTEFVFLGFSSLAGLQ--RLLFVAFLPLYL
FTLGTNAII-VSTIVLDRALHAPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTELMGHGVCVGLVAAACACGFTI
AQIITSMVFHLPFRASNQLRHYFCDIAPVLAVASHHSRLSQLVIFMIGVFVLVIPLLLIL
ISYIRIISAILK-IPSSTGRYKAFSTCASHLIVVTVHYGCASFIYLRPKSSYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNQEFKSALRRVMGHTSYPIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TISEFILSGFSACPQQLLPI----LFLLYLL-MF
LFTLLGNLL-IMATVWIERRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLFTHR-SITFVACAIQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNMLISPRGCAHLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FLCHVLS
-LLKLACENKTSSVIMGVMLVCVTALIGCLFLIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVTHYSFASFIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------NFCRRFCPLSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MRGFNKTT--VVTQFILVGFSSLG-ELQLL----LFVIFLL-LY
LTILVANVT-IMAVIRFSWTLHT--PMYGFLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSDTK-TISFMACATQLFF-FLGFAC-TNCLLIAVMGYDRCV-AICH
PLRYTLIMNKRLGLELISLSGATGSFI----ALVATNLICDMPFCGPNRVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKKKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-V--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNKEL---KTA---LKR------VLGMPVATKMS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------ICISIFSDPMK-RENYS--EVNEFIFQGFSSFQ-EHQIV----LFVVFLA-LY
ILTLAGNTI-IVTIISMDRHLHT--PMYFFLSMLSISETLYT--LV--------------
I-VPR---MLASLTGLNQ-PISKAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMDKKMCAKLLCGACSIGLTV----ATVQIASVFRLSFCETK-VPH-YFCDILQ
-VMKLSCAD-TTIHDIINLIISSLVIVVPMGLVFISYVLIIATILKIASAEGRQKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LCR------AVGRKPL----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RANHS--TVTQFILVGFSAFPHLQ-MM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSTQR-SVAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVGCSWAGGSVM----GMVVTSAIFHLTFCGPNEIYH-FACHVPP
-LLKLACGDDVLVVAKGVGLVCIMALLGCFLLILLSYAFIVAAILKIPSAEGRNKT----
-----F--------------STCASRLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFFSKLYPEKN
V---M-M------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-SENHT--VVGEFVLQGFSSFR-EHQII----LFVIFLT-LY
LFTLAGNVV-IVTVIGSARHLHT--PMYFFLSVLSVSETVYT--LV--------------
I-VPR---MLCSLMGLSR-RISRAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVVMSKRVCALLVWGAFSIGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMELSCAD-TTLHDIINFIISSLVIVVPMGLVFVSYVLIISTILKISSAQGRKKA----
-----F--------------ATCASHLIV-VIVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LHR------AISKNPHA---
-------------------------------

----------------------MECVNGSLVREFVFLGFSSLAGLQ--RLLFAVFLVVYL
FTLGTNAII-ISTVVLDRALHTPMYFFLAVLSCFETCYTFVIVPKMLVDLLAQKKAISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICDPLRYTVLMGHGVCVGLVAAACTCGFTV
AQIITSLVFHLPFHSSNQLHHFFCDISPVLKVASHHTHFSQIVIIMLCALVLIIPLLLIL
VSYICIISAILQ-FPSTLGRYKAFSTCASHLIIVIVHYGCASFIYLRLKSNYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRVVGRTICLS---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANYS--EVTEFILIGFSTFPH-LQMM----FFLLFLL-MY
LFTLLGNLL-IMVTIWSEHSLHT--PMYLFLCALSISEILYT--FA--------------
I-IPR---MLADLLSIHH-SITFLACANQMFF-SFTFGF-THSFLLTIMGYDRYV-AICH
PLRYNMLMSPQGCACLVAWSWAGGSIM----GMVVTTAIFHLTFCGPNEIHH-FACHVPP
-LLKLACGNGVPVVAKSVGLVCIMALLGCFLLILLSYIFIVATILNIPSVEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------TFLSKFYPE--
----------KM-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LSMANSS--AIIEFLLMGFSSLG-EFQLV----LFAVFLC-LY
LIILSGNVT-IISVICLDRSLHT--PMYFFLGILSTSEIFYT--LV--------------
I-LPK---MLINLFSVLR-TLSFVSCATQMFF-FLGFAV-SNCLLLGVMGYDRYA-AICQ
PLRYPILMSWRACGQLAATCIVSGFLV----SLVGTTVVFSLPFCGSNNINH-YFCDISP
-VIRLACAD-TYINELVIFICGVLVLVLPLLFICISYGFIVHTILKIPSAEGKRKA----
-----F--------------STCASHLIV-VTVHFGCASSVYLRPSAKN-T--SGKDR--
-LVTVTYTII-TPLL----NPMVYSLRNKDV---QVA---IRK------LIGKAGFSFKT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IL-FFPHSSLQIIPWEQLPQENQT--TITEFLLLGFSNLQ-EKQLV----LFPIFLC-LY
LLILSGNIT-IVTVICLEHSLHI--PMYFFLGVLSISETCYT--FV--------------
V-LPK---MLVNLFSVLR-TISFISCAVQMFF-FLGFGV-SNCLLLGVMGYDRYA-AICH
PLRYPILMNWRVCRLLAVTCGLSGFLI----SLVGTTLVFILPFCNSNKVEH-YFCDISP
-VIHLACGD-ASINEFVIFICGVLVLVFPLTFICISYGFIVSTILKIPSAEGKRKA----
-----F--------------STCASHLTV-VVVHYGCASFVYLRPS-RI-S--SSKDQ--
-LVTVTYTII-TPLL----NPLIYSLRNKDV---QIA---IRK------VITWG------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MVANVHCCFFQISSTPTMQINKT--ILKEFILVGFSVYP-DIQVF----IFVVFLC-LY
LFTLMGNMA-IMGLTWVDTALHT--PMYLFLSALSFSETCYT--MS--------------
I-IPK---MLADLLAKNR-SISIVGCGLQMCF-FLGLGG-THTIIFTLMGYDHFL-AICN
PLRYPLLTTNTVCGQLVASAWAGGFFI----SLIETSLIFRGVFCNHNLVKH-FFCHMRA
-VVKLSCLD-SDFTEFIVTVISVSGLLGTFFLIILTYIFILSTLLRIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-LIAIPYTVI-TPFL----SPLIFTLRNKDI---KNA---FRR------VLGKLVALNK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GANYS--GVTEFILIGFSTFPH-LQLM----FFLLFLL-MY
LFTLSGNLI-IMVTIWSEQSLHT--PMYLFLCALSISEILYT--LA--------------
I-IPH---MLVDLLSSLH-SIAFLACASQMFF-SFTFGF-THSFLLTIMGYDHYV-AICH
PLCYNVLMSPQGCACLVAWSWVGGSVV----GTMVTTAIFNLTFCGPNEIHH-FFCHVPP
-LLKLACGEDVLVVAKGVGLVCITVLLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVT---MKK------AFLKLPN-CV-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MT-GQNYS--TTSEFILFSFSAFPHQLLLA----LFLLYLL-MY
LFTLLGNLL-IMATVWTERQLHT--PMYTFLCALSISEILLT--IT--------------
I-TPR---MLGDLLSTNH-SITFVACAAQTFC-SFTFGY-AHSFLLMVMGYDRYV-AICH
PLRYNVFMNPTVCAHLVAWSWAGGSAV----GMIMTSIVFHLTFCESHVIHH-IFCHVFS
-LLKLACGDEMGSVTIGVILVCVIPLISNLILIILSYVFIVAAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VIVHNSFASMIYLKPKGPY---SVYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNS---INK------Y-YRKLCLKNP
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSFG-QHQIT----LFVVFLT-IY
IFTLAGNII-IVTITHKDHHLHI--PMYFFLSMLSSSETVYT--LV--------------
I-VPR---MLSGLIFHNL-PISLAGCATQMFF-FVTLAT-NNCFLLTAMGYDRYV-AICD
PLRYMVIMSKGMCAWLVCGSLGTGLVM----AVLHVPAMFSLPFCGTV-VEH-FFCDVYP
-VMKLSCVD-TTLNEIINYGVSSFVILVPIGLIFISYVLIISTILKIASAEGQKKA----
-----F--------------ATCASHLIV-VVVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------AVGRNTSLQI-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSLG-KHQIT----IFGVFLT-VY
ILTLAGNII-IVTIVCIDHYLHT--PMCFFLSMLASSEKVYT--LV--------------
I-V---------LIFHNQ-PISLAGCASQMFF-FVILAI-NNCFLLTAMGYDRYV-AVCR
PRRYNVIMSKGLCAQLVCGSFAI---------VLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCID-ITIDEIINYDVS---------LIFTSYVLIISSILKIASAEGWKKT----
-----F--------------ATCASRFTV-VIVPCGCFSIAYLKPKSEN---STEQDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNIT--EVTEFIFLGFSSFH-EHQLI----LFVVFLI-LY
TLTLAGNAI-IVTIIRVDRHLHT--PMYFFVSMLASSETVYT--LV--------------
I-IPR---MLSSLIAQNQ-PISLAGCTTQMFF-FLSLAI-NNCFLLVVMGYDRYV-AICN
PLRYTVIMSKRVCVQLTCGAFSIGLTL----ATVQVISIFTLPFCHRI-VGH-FFCDTLP
-VMKLSCID-TTINEIINFVVSLFVILVTMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHY-------------------------
------------------------------------------------------------
-------------------------------

----------------------MERSNETNVSEFVFLGFSALAGFQ--QLLFVVFLLLYL
FTLSTNAVI-LSTILLERALHTPMYFFLGILSSFETCYTFIIVPKMLVDLLAEKKTISFM
GCAVQMLTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMDHGMCLGLVAAACVCGLTV
ALVTTSLVFHLPFHSSNKLHHFFCDISPVLKLASQHTRFSQMVIFILGIFALVIPLLLIL
ASYIRIISAILK-IPSTVGRYKAFSTCASHLIVVTVHYGCASFIYLRPKTNYNSSQDVLI
SVSYTILTPLFNPM-IYSLRNKEFKAALRHAIGQNLCIKH--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MGQVN-VT--SWRGFVFLGFTTFV-ELQLL----LFALFLC-LY
LVTLTSNVF-IIVII-------------------RLDKTCYT--LA--------------
I-IPR---MLSGLALGVH-TISYMGCAAQMFF-AGSWAC-ANCFLLCVMGFHRYV-AICT
PLHYASCLNPTFCSQMVGISFLSGYLF----GLGMTLVIFHLSFCSSHGIQH-FFCDTPP
-VLSLACGD-TGLSELGLLILSLLVLLVSFFIITISYAYILAAILRLSSAEGPKAS----
---------------------------------------------------YSLEQDQ--
-LIAVTYTVM-TPLL----NSIIYTLRNAFC---GSL---LGK------G----------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLISSMK-KVNLT--EVREFVFQGFANFQ-EHQLT----LFVVFLA-LY
ILTLTGNVI-IVTIIRIDHHLHT--PMYFFLCVLSTSETFYS--LV--------------
I-IPR---MLSSLVGLGE-PISLAGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMSKRVCLQLVWGAFSIGLIV----AMTQVSAVFRLPFCTSL-VAH-FFCDIRP
-VMKLSCID-TTANEILTLVISVLVILIPMGLVFISYILIISTILKIASAEGRRKA----
-----F--------------ATCASHITV-VFVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LCR------AMGRKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHT--STSEFILLGFSTFPQQLLPV----FFLLFLL-MY
LFTLLGNLL-IMATIGSERSLHT--PMYLFLCALSVSEILYT--VA--------------
I-IPR---MLADLLSAHR-SISLLACACQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVGWSWAGGSAV----GLVVTTAIFQLTFCVSNEIQH-FLCHVPP
-LLKLACGHNLPAVALGVGLVCITALLGCFLLILLSYAFIVATILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKCPH---SQEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KIA---LKK------TFLRKRDSSGP
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GLNHS--SVSEFILIGFSPFPHLQ-LM----FFLLFLL-MY
LFTLLGNLL-ILTTIWGERSLHT--PMYLFLCALSISEILYT--FA--------------
I-VPR---MLADLLSTHR-SIAFVACASQMYF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCACLVAWSWAGGSVM----GLVVTMAIFHLPFCGPNEVHH-LGCHALP
-LLKLACGNNVSTVALGVGLVCITALLGCCLLILLSYASIIATILRMPSAEGRQKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKSKGPQ---SLEGDT--
-LMGVTYTVL-TPFL----SPIIFSLRNKEL---KSA---MKR------TVLSRLLLQSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNST--FVTEFLFEGFSSFRWQYRLV----FFVVFLT-LY
LLTLSGNVI-IMTIVRLDHHLHTPHPMYFFLSMLSIFETCYT--VA--------------
I-VPY---MLSGLLNPHQ-PVATHSCATQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRCSVIMSKRACIQLASVSLG--I----------VTSVFGLLFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVCVLVLPMDLVFVFYVLIISTILTIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPNDLHCHHSPTEHC--
-----C----------------VQP---EEQ---GDA---LRC------SVQSHGAKAPV
SFTKR-------------GCEAFFFEFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AHNWS--TVTEFILIGFSTFPQHLLPI----FFFLYLL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILFT--VA--------------
V-TPR---MLVDMLSTHH-SITFVACASQMFF-SFTFGF-THSFLLMIMGYDRYV-AICH
PLRYNVLMSPRDCVRLVSWSWAGGSVM----GMMVTLIVFHLTFCGSNMIHH-FLCHVLS
-LLKLSCGRETSSVTLGVILVCVTALMGCLFLIFLSYVFIVSAILRIPSAEGRHKT----
-----F--------------STCVSHLTV-VVVHYGFASIIYLKPKGPH---SMDSNT--
-LMATTYTVV-TPFL----SPIIFSLRNKEL---KNA---IKK------SFLRKFCPLNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RANHT--ELREFVFQGFSNFQ-EHQLT----FFVVFLA-LY
ILTLAGNF--------------------------HHSETFYS--LV--------------
I-IPC---MLSSLVGLSQ-PISLEGCGTQIFF-FLGFAI-TNCLLLAVMEYDHYV-AICN
PLRYSVIMNCRVCAILASSVCATGFSL----SLVQTVAIFRLLFCTPL-IEH-FFCDVQP
-VLDLAWAT-PMINDILTLIMSLLAITAPATFLSISYVLIISTILKITSAEGGKKT----
-----F--------------ATCASHLTA-VIIHYGCASIAYFKPNLEN---TKDQDQ--
-LISVTYTVI-TPLL----NPVVYGLRNKEV---QDA---LQR------VLGRKFFS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-KSNAT--FVTEFLFEGFSSFGWQHRLA----FFAIFLT-LY
FLTLSGNVI-IVSIIQLDHHLHT--PMYFFLAILSISDTCYX--VT--------------
I-IPR---MLSDLLHPFH-TXAFRDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGRKACVHLASGSLGIGLDM----AIVQVTSVFSLPFCDRFVIPH-FFCDVRP
-LLKLACTD-TXVNXIINFVVXVCVLILPMVVVFISYVVIVSTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYMKPKSQS---LLGQXR--
-LISVTYTLI-TPLL----NPLVYTLRNKEV---KDA---LRR------ALWQKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------QAPEKQQDNGTW--PVTEFILVGFSNLP-DLRPT----LFILFLL-TY
LVTLSGNAT-IITIIQVDHTLHT--PMYRFLAVLSLSETCYM--LV--------------
T-IPN---MLAHLLMESQ-VISIAGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTVCLCLGALVFCSGFSV----ALIETCMIFSSPFCGAGHVEH-FFCDIAP
-VLKLSCAE-SSLKALGIFFLSILVVLFSFLLILLSYAFIVAAIVRIPSAAGRRKA----
-----F--------------STCAAHLTV-VIVHFGCVSIIYLRPDSGA-N--PSQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRK------NLARGCGVFK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------ARTSML-GPNQT--TVSEFILIGFSPFPQ-LQLL----FFVLFLL-MY
LFTLLGNLL-IMLTVWHERNLHK--PMYFFLCTLSISEIAYT--LA--------------
I-NPR---MLADLISTHH-TISLWGCANQMFF-TFSCGL-AHAFLLTIMGYDRYV-AICH
PLRYGVLMSSQGCAWLVASSWLSGIVM----GLVITLPIFSLTFCGPNEIHH-FFCQVPP
-LVKLACGD-VSAVALGIGVVYIIVLLVCFLLILLSYIFIVATILKIPSAEGRHKA----
-----F--------------STCASHLIV-VVIHYSFASVAHLKAKALE---ALEGDT--
-LMGISYSVL-TPFL----SPIIFSLRNKEL---KDA---LKK------VFLRNLCPSRL
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GLNRT--STSEFILASFSTFPQQLLPV----FFLLFLL-MY
LFMLLGSLL-IMATVWSERSLHT--PMYLFLCALSISEVLYT--VA--------------
I-IPR---MLADLLSAHH-SITLLACASQMFS-SFTFGF-THSFLLTVMGYNCYV-AICH
PLCYHVLMSPHGCACLVGWSWAGGFMV----GMVVTTAIFQLTFCGSHEIQH-FLGHVPP
-LLKLACGHHVPAVVLGVGLVCIMALLSCFLLILLSYAFIVATILKIPSAEARHKA----
-----F--------------STCASDLTV-VIVHYGFASVIYFKTKGSH---SQEGDT--
-LMGTTYTVL-TPFL----SPIIFSLRNKEL---KVA---LKK------TFLGKLHSSGT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
KVLPTYTSCFAKISELHMMKINQT--VLKEFILVGFSVYP-HAQTF----LFVVFFC-LY
LPTLTGNLA-IMGLTWVDRRLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLSDLLAKDR-SISSIGCGLQMCF-FLGLGG-TNCAILTWMGYDRFL-AICN
PLRYPLLMTNMVCGKCVASAWIAGFFV----SVIETALIFRGSFCNPNLVKH-FFCHMRA
-VVRLSCLD-SDLTEFTVTVMSVSGLMGTFLVIILTYVFILSTVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAS-----GGDDT--
-VIAVPYTVV-TPFL----SPLIFSLRNKDM---KNA---FRK------ILRNFLNNLV-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MI-KSNTT--FVTEFLFEGFSGFGWQHRLA----FFAIFLA-LY
FLTLSGNVI-IVSIIHLDHHLHT--PMYFFLAILSISDTCYT--VT--------------
I-IPR---MLSDLLNPYH-TIAFRDCVVQIFF-YLTFGI-NNCFLLMVMGYDRYV-AICN
PLRYSVIMGRKACVHLASGSLGIGLGM----AIVQVTSVFSLPFCDRFVIPH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVFVLILPMGVVFISYVVIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCTAIIYMKPKSQS---LLGQER--
-LISVTYTLI-TPLL----NPLVYTLRNKEV---KDA---LRR------AMWQKPLSS--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MV-LHNGT--FWRGFVFLGFSSFG-ELQLL----LFTLFLC-LY
LVTLTSNVF-IIVLIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLVVGGQ-SISYVGCAAQMFF-SASWAC-SDCFLLAVMGFDRYV-AICT
PLHYASRMHPTLCAQLIGASFLSGYLF----GLGMTLVIFHLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TALSELGILLLSLLVLLASFFFLTVSYAYILAAILRIPSAEGRKKA----
-----F--------------STCASHLTV-VIIHYGCASFMYLRPKAS---YSLERDQ--
-LIAVTYTVV-TPLL----NPIVYSLRNRAV---QTA---VR-------TAFQGSLLGKG
-------------------------------

------------------------------------------------------------
----------------------------------ETCYTFVIVPKMLVDLLSQKKTISFQ
GCAIQLFTFLFLGCSHSFLLAAVGYDRCVAICNPLRYTVLMGHGVCVGLVAAAWACGFSV
SLVTTSLVFHLPFCSSNQLHHFFCDISPVLKVASHHNRLSHIVIFMLCALVLVIPLLLIL
VSYICIISAILQ-FPSTLGRCKAFSTCASHLIIVTVHYGFASFIYLRPKSNYSSSRDAPI
SVTYTILTPLFNPM-IYSLRNKEFKSALHRVVGRIISLQ---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MT-RRNHT--VVIEFVFQGFSSFQ-EYKFT----LFMVFLA-LY
LLTLTGNAI-IMIVISIDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-VPR---MLASLVGSSQ-SISLAGCATQMFF-FITLAI-TNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCAQLVWGSCSIGLLV----AIIQIASVFRAPFCDGD-VAH-YFCDIRP
-VLKLSCAD-TTLHDIVNFIISSLVIVVPMGLVFISYILIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSKN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---IFR------AIGKKPLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MINQT--ILQEFILIGFSVYP-HVQTC----LFVVFLC-LY
MVTLAGNLT-IMGLTWVDRSLHT--PMYFFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLDKDN-RISVIGCGLQMCF-FLGLGG-THCILLTVMGYDRFL-AICN
PLRYPLLMTNVACGQLVASAWVGGFFI----SLIETTLIFRVSFCIPNLIRH-FFCHMRA
-VLRLSCTD-SNFTEFVVTLMSVSGLLGTFLLILLTYMFILSSVLKIPSAEGKQKA----
-----F--------------STCASHLTV-VFIHFGFASVVYMKPENS-----GGDDT--
-LIAVPYTVI-TPFL----SPIIFTLRNKDM---KNA---FRK------IMRKTVVLKK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MD----N-HT--TGNTFLLWGFSSFP-ELQTL-----LFVVIFSSH
VTILLANVS-VMVAIKLNHNLHT--PMYFFLFGLSFSETCTT--MV--------------
I-IPR---MLVDLLSDSK-TISLPECATQMFF-FFGLGG-NNCFILATMSYDRYI-AIHN
PLQYPMLMTKKICFQLIMASCIIGFLV----SGCIAVIIFTFSFCDSHTIQH-FFCDILP
-VASLACDY-TPFHEMAICMLCAFVLVGSFILIVISYVFILSLVLKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFACYIYLRPKSR---DSFREDM--
-LMAVTYTVL-TPLL----NPIVYSLRNKEM---QVA---LWK------VLENGHRFISR
W------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---INVDCCIILNKTIKQWENGTW--LVKEFLLVGFSNFP-DLRIK----LFMVFLL-TY
LVTLSGNIT-IITIIHVDRTLHT--PMYRFLAVLSLSETCYT--LV--------------
T-IPN---MLAHLLMESQ-AISISGCRAQMFF-FLGLGC-SHCFLLTLMGYDRYV-AICH
PLRYSVIMRPTICLCLGALVFCCGFSV----ALIETSMIFWSPFCRGGRVEH-FFCDIAP
-VLKLSCVE-SSRKALGIFFLSVLVVLVSFLLILLSYAFIVAAIVRIQSAASRRKA----
-----F--------------STCVAHLTV-VIVHFGCASVIYLRPESGS-N--PDQDR--
-LVAVFYTVV-TPLL----NPVVYTLRNKEV---RVA---LRS------ILARSGGGLK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------RRMDN-HT--TVSTFLLWGFSSFP-DLQDL-----FVMVFF-SH
VTILAANVS-IMVAVKLNHSLHI--PMYFFLCGLSFSETCTT--VV--------------
V-IPR---MLVDLLSDSK-AISIFECAAQMFF-FFGLSG-NNCFIMAAMSYDRYT-AIHN
PLHYSILMTLKICFQLMMAAWLVGFLV----SMCIVTIVFNLSFCDSNTIQH-FFCDISP
-VVCLACDY-TLSYEMAIFVLSAFVLVGSFILIMISYVFIGSIVMKMPSAKGRYKA----
-----F--------------STCSSHLTV-VCIHYGFAGFVYLRPKSS---DSFREDM--
-LMALTYTVL-TPLL----NPIVYSLRNKEM---QIA---LRK------IVDSANRFI--
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MANSS--FVTEFLLLGFSGLG-ELQLV----LFVVFLP-LY
LVILSGNLT-IISVIHLDSNLHT--PMYFFLCVLSTSETLYT--IV--------------
I-LPK---MLINLFSVLR-TLSFMSCATQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICQ
PLHYPILMHWRICGQLALSCIVCGFLT----SLLGTAPVFSLPFCASNKVDH-YFCDISP
-VIRLACAD-TRINELVIFIGGALVLLVPFVFICISYGFIVRTILRIPSTEGKRKA----
-----F--------------STCASHLTV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-SQNYS--IISEFNLFGFSAFPQHLLPI----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSISEILFT--VA--------------
I-TPR---MLADLLSTHH-SITFVACANQMFF-SFMFGF-THSFLLMVMGYDRYV-AICH
PLRYNVLMSPRDCACLVACTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FFCHVLS
-LLKLACENKTSSVIMGVMLVCVTALIGCLFLNILSYVFIVAAILRIPSAEGQHKT----
-----F--------------STCVSHLTV-VVTHYSFASFIYLKPKGLH---SMYSDA--
-LMATTYTVF-TPFL----SLIIFSLRNKEL---KNA---INK------NFYRKFCPPSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----ILLHFRFGNHSMK-RENCT--LITEFTFQGFSSFH-EYQLT----LFVVFLT-LY
ILTIAGNVI-IVTIIRIDHHLHT--PMYFFLSMLSTSETIYT--LV--------------
I-LPR---MLSSLVGMSQ-SISLAGCATQMFL-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYTVIMNKRVCIQLVWGACSIGLIV----AITQVTSVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVLVVPMGLVFISYVLIISTILNIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---KDA---LHR------AIGLKHS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MFLCFRFGNQSMK-TENFT--LITDFVFQGFSSFR-EQQIT----LFGVFLA-LY
ILTLAGTTI-IVTIIQIDHHLNT--PMNFFLSMQSTSETVYT--LV--------------
I-LPR---MLFSLVGMNQ-TISLAG----------------------SMGYDCYV-AICN
PLRYTVIMNKRVRIQLVLGACSIGLIV----AITQVTAVCRLLFCARK-VPH-FFCDIRP
-EMKLSCID-TTVNEILTLIISVLVLVV-------SL-----------------------
------------------------------------------------------------
-----------------------------EV---KDA---LCR------AVGGKFS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MA-KPNST--FVT--------DFRWQHRLA----FFVVFLT-LY
LLTLSGNVI-IMTIIRLDHHLHT--PMYFFLSMLSISETCYT--VA--------------
I-IPR---MLSGLLNPYQ-PIAIQGCATQLFF-YLTFGI-NNCFLLTVMGYDRCV-AICN
PLRYSVIMGKRACVQLASGSLGIGLGM----TIVQVTSVFGLPFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSICVLVLPMGLVFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLIV-VIIHYGCASIIYLKPKSQS---SLGQDR--
-LISVTYT----------------P---EEQ---G-G---QRC------SAQGRGAKAPV
TLMRR-------------GCKRFFFEFINMC

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------IYISYFSDPMK-RENYS--EVSEFIFQGFSNFQ-EHQIT----LFMVFLA-LY
ILTLAGNAI-IVTIISMDRHLHT--PMYFFLSMLSISETFYT--LV--------------
I-VPR---MLASLTGLNQ-PISLAGCATQMFC-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMDKKMCTKLICGSCAIGLTI----ATVQIASVFRLPFCDAR-VPH-YFCDILP
-IMMLSCVD-TSIHDIINFIISSLVIVVPMGLVFISYVLIISTILKIASAEGRQKA----
-----F--------------ATCASHLTV-VIIHYGCASIAYLKPKSEN---TRDQDQ--
-LISVTYTVF-TPLL----NPVVYTLRNKEV---KDA---LRR------AVGRKSL----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVAEFIFLGFSIFG-NHQIT----LFVVFLS-TY
IFTLTGNII-VITVICIDRHLHT--PMYFFLSMLSSSETVYT--LV--------------
I-IPR---MLSGLIFYNQ-PISLGSCATQMFF-FAILAA-NNCFLLTVMSYDHYV-AICK
PLRYTVLMNKGVCARLVCGSFGTGLVM----AVLHVTAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCID-TTVNEIINYGVSSFVIIVPVVLVFISYILIISSILKIPSVEGRKKT----
-----F--------------ATCASHLTV-VVVHYGCAAIAYLKPKSEN---AIEEDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGRNSS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-GPNYT--SVSEFIFIGFSNFPRQLMPV----FFVVILL-MY
LFTLLGNLL-IMATIWSDRNLHT--PMYLFLCALSISEILYT--LS--------------
F-IPR---MLADLLSTHH-SITFLACANQMFF-SFMFGF-THSLLLTVMGYDRYV-AICH
PLHYNVLMSPRGCAFLVAGSWAGGSAV----GLVVTTSIFHLPFCGPNQIQH-FLCHVPP
-MLKLACGSDVPPVALGVGLICITALLGCFLLILLSYTFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGPH---FEEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KNA---MKK------AFLRKFCSSNT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MHSFNKTT--VVTQFILVGFSSLK-ELQLL----LFVLFLL-LY
LTILLANAT-IMVVIRFSRTLHT--PMYGLLFILSFSESCYT--FV--------------
I-IPQ---LLVHLLSATK-TISFTACTTQLFF-FLGFAC-TNCFLIAVMGYDRYV-AICH
PLRYTLIMNKTFGLGLVSLSAFTGFLI----ALVATNLICEMPFCGPNKVNH-YFCDMAP
-VIKLACTD-THVKELALFSLSILVIMVPFLLILISYGFILNTILKIPSAEGKRKA----
-----F--------------ATCASHLTV-VFVHYGCASIIYLRPKSKS-A--SDKDQ--
-LVAVTYTVV-TPLL----NPLVYSLRNQEV---KTA---LKR------VLGKSVNTKGG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------M--ASDRICAGGFSNLP-HLRTT----LFTLLLL-TY
LVTLSGNVT-IITIVHVDRTLHK--PM---------------------------------
------------------------------FF-FLGLGC-SHCFLLTLMGYDRFV-AICH
PLRYSVIMRPTICVRLGASVFCSGFSV----ALIETCMIFSSPFCRGDRVER-FFCDIAP
-VLRLSCTQ-GASKALGIFFLSVLVVLVSFLLILLSYALIVATVVKMPSGTGRHKA----
-----F--------------STCAAHLTM-VMVHFGCAAIIYLRPDSG---AHPEQDR--
-RVAVFYTVA-TPLL----NPVVYTLRNKEV---RVA---LRR------SLARGCGSLP-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MITVLGSEVVLAENIT--MVTEFLLLGFSSLG-EIQLA----LFAVFLF-LY
LAILSGNVT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLVNLLSVAR-IISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCSANKVNH-YFCDISP
-VIHLACTN-TDVNEFLIFICGVLVLVVPFLFICVSYLCILRTILKISSAEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASFIYLRPTASY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLGKKGSLKLQ
N------------------------------

----------------------MEQVNETMVREFVFLGFSSLARLQ--LLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAVLSCSETCYTFVIVPKMLVDLLAQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYVAICSPLHYTVLMGPRVCLGLVAAACAGGFTV
SLVTSSLVFHLPFHSSNQLHHFFCDISPVLKLASHHSRLSQLVIFMLGVFVLVIPLLLIL
VSYTRIISAILR-IPSSVGRYKTFSTCASHLIVVTLHYGCASFIYLRPKSNYSSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRAMGQTLY-PVN-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GLNHT--SVSEFILVGFSAFPHLQ-LM----LFLLFLL-MY
LFTLLGNLL-IMATVWSERSLHM--PMYLFLCALSITEILYT--VA--------------
I-IPR---MLADLLSTQR-SIAFLACASQMFF-SFSFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSLRGCTCRVGCSWAGGLVM----GMVVTSAIFHLAFCGHKEIHH-FFCHVPP
-LLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SPEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TCFTKLFPQNC
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------LGDRVNQANFS--SVTEFVLLGFSNLG-EIQLI----LFAVFLC-LY
LIILSGNLT-IITVIRLDRSLHV--PMYFFLGILSISETCYT--FV--------------
I-LPK---MLLNLLSLLR-TISFINCAIQMFF-FLGFAV-TNCMLLGVMGYDRYA-AICH
PLRYPILMRWQVCGQLAATCAVIGFLF----SLTGSFLVFELPFCGPNKINH-YFCDISP
-VIQLACTE-TYINELVIFAGGVLALMVPLTFICISYGFIVRTILKIPSTDGKRKA----
-----F--------------STCASHLTV-VIVHYGCASSVYLRPSTKF-S--SNKDR--
-LVTVTYTVV-TPLL----NPMVYSLRNKDV---QMA---IRK------VIARELETGVL
GCADQVHS-IS--------------------

----------------------MERINETVVREFVFLGFSSLARLQ--QLLFVIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLAILSCSETCYTFVIVPKMLVDLLSQKKTISFL
GCAIQMFSFLFLGCSHSFLLAAMGYDRYMAICNPLHYSVLMGHGVCMGLVAAACACGFTV
SLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLIL
VSYIRIISAILK-IPSSVGRYKTFSTCASHLIVVTVHYGCASFIYLRPKTIYTSSQDTLI
SVSYTILTPLFNPM-IYSLRNKEFKSALQRTIGQTLYPLN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GHNYS--TTSGFILFGFSAFPHQLLPA----LFLLYLL-MY
LFTLLGNLL-IMATVWTERQLHT--PMYLFLCALSISEILFT--IA--------------
I-TPR---MLADLLSTHH-SITFVACAMQTFF-CFTFGY-THSFLLMVMGYDRYV-AICH
PLRYNVFMNPTVCAHLVAWSWAGGSVM----GMIMTSIVFHLTFCESHVIHH-IFCHVFS
-LLKLACGDEMGFVTIGVILVCVIPLVGCLSLIILSYVFIVSAILRIPSPEGRHKT----
-----F--------------STCVSHLSI-VIVHYSFASMIYLKPKGPH---SVYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNS---INK------TYHRKLCLQNP
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------IPV
FV-YLN---MFYLFPFQVLAKNLT--MVTEFLLLGFSSLG-EIQLA----LFVVFLS-LY
LVILSGNVT-IVNIIRLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLLNLLSVAR-TISFICCAIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWHVCGKLGATCGIGGFLA----SLTVVYLVFSLPFCSANKVNH-YFCDISP
-VIRLACTN-TDVHEFVIFICGVLVLVVPFSLICVSYVCILRTILKIPSTEGRRKA----
-----F--------------STCASHLTV-VIIHYGCASYIYLRPTANF-V--SNRDR--
-LVTVTYTIV-TPLL----NPIVYSLRNKDV---QVA---IRK------ALGKKGSLKFY
N------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KENHT--VVSEFVLQGFSSLH-EYQLT----LFIVFLA-LY
ILTLSGNVI-IVTIIGLDHHLHT--PMYFFLSMLSASETVYT--LV--------------
V-IPR---MLSNLVGLNE-PISLGGCATQMFF-FITLAI-NNCFLLTAMGYDRYV-AICN
PLRYSVIMNKRMCIQLVWGACGTGLTV----AVTQVSAVFRLPFCASE-VAH-FFCDIRP
-VMKLSCID-TTVNEILTLIISVLVILVPMSLIFITYIFIISTILKIASAEGRKKA----
-----F--------------ATCASHITV-VIVHYGCASIAYLKPKSEN---TKDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---REA---LCR------AIGKKLS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------VMAENLT--MVTEFLLIGFSSLG-EIQLA----LFVVFLF-LY
LVILSGNVT-IISIIRLDRNLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISYTCCVIQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMSWQMCGKLAAACGFGGFLA----SPMVVNLVFSLPFCNANKVNH-YFCDISP
-VIRLACTN-TDVHEFVIFICGVLVLVVPFFFVCISYLCILRTILKIPSVEGRKKS----
-----F--------------STCSSHLTV-VIIHYGCASFIYLRPTASY-V--SNKDR--
-LVMVIYTIV-TPLL----NPMVYSLRNKDV---QFA---LRR------VLGKKVTL---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------IYIYTSKHEGRVRNKKGGNRTL
HDNFNIYLKSIIEDHSMR-RHNRT--EVSEFFFQGFSSFQ-EHQIT----LFVVFLA-LY
IFTLAGNVI-IVIIIRIDSHLHT--PMYFFLSMLSTSETLYS--LV--------------
I-IPQ---MLSSLVSRDM-SISLAGCATQMFF-FVTFAI-NNCFLLTAMGYDRYV-AICN
PLRYTVIMNRKVCALLIWVAFSIGLIV----AVTQVTSVFRLPFCGVE-VAH-FFCDIRP
-VMKLSCID-TTINEILTLIISVLVLLVPMGLVFISYVLIISTILKIASAEGRQKA----
-----F--------------ATCASHLTV-VIVHYGCAAIAYLKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---KDA---LLR------VFEEKTYS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VAAML-GLNHS--FVSEFILIGFSTFPH-LQMV----FFLLFLL-MY
LFTLLGNLF-IMATIWSERSLHT--PMYLFLCALSISEIFYT--FA--------------
I-IPR---MLVDLLWPLH-SIAFLACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVAWSWVGGSFM----GTVVTTAIFNLTFCGPNEIHH-FACHVPP
-LLKLACGGNVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLTV-VIVHYGFASVIYLKPKGPK---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVT---MKK------AFLNKLFLQ--
----------N--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MG-QTNVT--SWRDFVFLGFSSSG-ELQLL----LFALFLS-LY
LVTLTSNVF-IIIAIRLDSHLHT--PMYLFLSFLSFSETCYT--LG--------------
I-IPR---MLSGLAGGDQ-AISYVGCAAQMFF-SASWAC-TNCFLLAAMGFDRYV-AICA
PLHYASHMNPTLCAQLVITSFLTGYLF----GLGMTLVIFHLSFCSSHEIQH-FFCDTPP
-VLSLACGD-TGPSELRIFILSLLVLLVSFFFITISYAYILAAILRIPSAEGQKKA----
-----F--------------STCASHLTV-VIIHYGCASFVYLRPKAS---YSLERDQ--
-LIAMTYTVV-TPLL----NPIVYSLRNRAI---QTA---LR-------NAFRGRLLGKG
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------SDSATMKTNQT--VLMEFILVGFSLYP-QVQTF----FFVVFLG-LY
LLTLTGNLS-IMGLTWADRYLHT--PMYLFLSALSFSETCYT--AA--------------
I-IPR---MLADLLTRSR-RISLTGCGLQMLF-FLGLGG-TNCIILTLMGYDRFL-AICN
PLRYPLLMTNVVCGRLVAFAWVGGFLI----SLVETTLIFQGSFCGPNHIQH-FFCHMRA
-VVRLSCVD-SDRTAIVVTVISVSGLLGTFLLIIFTYVFILSTVLRIPSTEGKQKA----
-----F--------------STCASHLTV-VLIHFGFASIVYLNPEAS-----GGEDI--
-FIAIPYTVI-TPFL----SPLIFSLRNKDM---KNA---LRK------VLGSRVALRK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNTT--AVTEFTFEGFSALGWQRRLL----LFVVFLA-LH
LVTLGSNAL-ILAAVRLSRHLHT--PMYFLLSALSLSETCYS--VA--------------
I-VPR---MLSGLLSPRE-AVSVAGCATQLFF-YLTFGV-TNCFLLAAMGYDRYV-AICD
PLRYAVVMGQRTCVHLACGSWSVGLST----AIIQVSSVFSLPFCDASVISH-FFCDIRP
-LMKLACAD-TTIKELLTLLISLCVLVLPMVLIFISYVLIVSTILKMASAEGQRKA----
-----F--------------ATCASHLTV-VIVHYGCTSFIYLKPKSQN---SL-QDR--
-LLSVTYTVI-TPLL----NPVVYGLRNKEV---KQA---LLR------AVGRKPLP---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MLSSLLFHDQ-PISLVGCATQMFL-FVTLAT-NNCFLLTAMGYDRYV-AICN
PLHYSLIMSKGICIGLVCGSFITGLIM----AVLHVTAMFNLPFCGTV-VDH-FFCDIYP
-VMKLSCVD-TTINEIINYGVISFVILVPVALIFISYVLIISSILRITTAEGRKKA----
-----F--------------ATCGSHLTV-VIIHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KVA---LQR------AMGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-KPNST--FVIEFLFEGFSSFRWQCRLV----FFVVFLT-LY
LLTLSGNVI-IMTIVRLDHHLHTPHPMYFFLSMLSIFETCYT--VA--------------
I-IPY---MLSGLLNPHQ-PVATHSCAIQLFF-YLTFGI-NNCFLLTVMGYDRYV-AICN
PLRCSVIMSKRACIQLASVSLGIGL----------LTSVFGLLFCDAFVISH-FFCDVRP
-LLKLACTD-TTVNEIINFVVSVFVLVLPMDLVFVSYVLIISTILTIASAEGWKKA----
-----F--------------ATCASHLTV-VIIHYGCASIIYLKPNDLHCHHSPTEHC--
-----C----------------VQP---EEQ---GDA---LRC------SAQSHGAKAPV
SFTKR-------------GCEAFFFEFINMY

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YFFLCVLSISETFYT--VV--------------
I-LPK---MLINLPSLLR-TLSFVSCATQMFF-FLGFAV-TNCLLLGVMGYDRYA-AICQ
PLHYPVLMSWSVSGQLAATCIVSGFVI----SLAGTILVFSLPFCGPNQVDH-YFCDISP
-IIHLACAD-THINELLIFIGGVLVLVVPLFFICVSYGFIVRTILRIPSAEGKRKA----
-----F--------------STCASHLTV-VIVHYGC-----------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------ML-RPNYT--SVSEFIFIGFSNFPQQLMPV----FFVVILL-MY
LFTLLGNLL-IMATIWSERSLHT--PMYLFLCALSISEILYT--LS--------------
F-IPR---MLVDLLSTHR-SIAFLACANQMFF-SFMFGF-THSLLLTIMGYDRYV-AICH
PLHYNVLMSPRGCAFLVAGSWAGGSAV----GLVVTTSIFHLPFCGPNQIQH-FLCHVPP
-MLKLACGRNVPAVALGVGMVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKA----
-----F--------------STCASHLIV-VIVHYGFASVIYLKPKGPH---LEEGDT--
-LMATTYTVL-TPFL----SPIIFSLRNKEL---KNA---INK------AFFRKFCSSNT
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-KTNCT--HVREFVFQGFSNFQ-EHQLT----LFVVFFV-LY
ILTLAGNVI-IVTIIRIDHHLHT--PMYFFLSVLSTSETFYS--LV--------------
I-IPR---MLGSLVGLSQ-TISLECCGTQLFF-FLGFAI-TNCLLLAVMGYDRYV-AICN
PLRYSVIMNWRVCVILASSVGATGFLL----SLIQAVAIFRLPFCNTL-IEH-FFCDVRP
-ILDLACTV-PVINDILTLALSLMVITAPATFLFVSYVLIISTILKIASAEGRRKT----
-----F--------------ATCASHLTV-VVIHYGCASIAYFKPKSEN---TRDQDQ--
-LISVTYTVI-TPLL----NPVVYSLRNKEV---QDA---LRK------VLGKKSLS---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------RMHN-HS--TVSTFILWGFSSFP-DLQRL----LFVVIFF-SH
VTILAANVS-IMLAIKLSHSLHT--PMYFFLFGLSLSETCTT--MV--------------
I-IPR---VLVDLLSESK-TISLPECATQMFF-FFTLAG-NNCFILAAMSYDRYT-AIHS
PLYYPILMTHKVCFLLMMASCIVGILI----SLCITTIVFNLSYCDSNIIQH-FFCDFAP
-VVHLACDY-TSYHEIAIFVLSAFVLLGSFVLIMVSYVFIITVIMKMPSTEGRYKA----
-----F--------------STCSSHFTV-VSIHYGFACFVYLRPKGS---DTFREDM--
-LMAVTYTVL-TPLL----NPIIYSLRNKEM---RIA---LRK------ILDNGNRFVLQ
LS-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GENYS--SISEFILFGFSAFPQQMLPA----LFLLYLL-MY
LFTLLGNLL-IMAAVWTEHRLHT--PMYLFLCALSISEILFT--VV--------------
I-TPR---MLADLMSTHR-SITFIACANQLFF-SFTFGY-THSFLLMVMGYDRYV-AICR
PLHYHVLMNLQGCARLVAWSWVGGSLI----GMTVTLIIFHLTFCESNVIHH-LLCHVFS
-LLKLACGERATSVTIVVILVCVTPLIGCLVLIVLSYIFIVAAILRISSTEGRHKT----
-----F--------------STCASHLTV-VVVHYGFASIIYLKSRGPH---SLYTDT--
-LMSTTYTVF-TPFL----SPIIFSLRNKEL---KNA---INK------SFHRNFCQRSS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RGNFS--VVTEFILVGFSTFPH-LQLM----FFLLFLL-MY
LFTLLGNLL-IMATVGSERGLHT--PMYLFLCALSISEILYT--LA--------------
I-TPR---LLADLLSTHH-TITSMACASQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPRGCTCLVVWSWVGGLVM----GLVVTTAVFHLTFCGPNEIHH-FACHVPP
-LLKLACGTDVPIVALGVGLVCITALLGCFLLILLSYAFIVAAILRIPSAEGRHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKAPQ---SLEGDT--
-LMGITYTIL-TPFL----SPIIFSLRNKEL---KTA---MKK------TFLSKLYPEKR
V---M--W-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MTTVLGSEVILTENLT--TVTEFLLLGFSSLG-EIQLA----LFVAFLF-LY
LVILSGNIT-IISVIHLDKSLHT--PMYFFLGILSTSETFYT--FV--------------
I-LPK---MLINLLSVAR-TISFTCCALQMFF-FLGFAI-TNCLLLGVMGYDRYA-AICH
PLHYPILMGWQVCGKLAAACAIGGFLA----SLTVVNLVFSLPFCGANKVNH-YFCDISP
-VIRLACTN-TDVNEFVIFICGVLALVVPFLFICVSYICILRTILKIPSAEGRRKA----
-----F--------------STCAAHLTV-VIVHYGCASFIYLRPTANY-V--SNKDR--
-LVTVTYTIV-TPLL----NPMVYSLRNKDV---QLA---IRK------VLHKKGSLKLN
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MLMS-QPNCT--FVTKFLFAGFSTFGWQHRLV----FFVVFLM-LY
LVTLSGNVI-IVTIIHLDRHLHT--PMYFFLSILSISDTCYT--VV--------------
I-IPR---MLYGLLNPQQ-TISFQDCATQLFF-YLTFGI-NNCFLLMAMGYDRYV-AICN
PLRYSVIIGKRACNHLVLGSLGIGLSM----AIVQVTSVFSLPFCDAFVIPH-FFCDVRP
-LLKLACTN-TTVSEIINFVVSVFVLILPMGVVFISYVLIISTILKIASKEGRKKA----
-----F--------------ATCTSHLTV-VIIHYGCTSIIYLQPKSQS---FLGQDR--
-LISVTYTVI-TPLL----NPLVYSLRNKEV---KDA---LCK------ALGKKPISS--
-------------------------------

----------------------MEWVNETVVREFVFLGFSSLARLQ--LLLFAIFLLLYL
FTLGTNAII-ISTIVLDRALHTPMYFFLSVLSCSETCYTFVIVPKMLVDLLAQRKTISFL
GCAIQMFTFLFLGCSHSFLLAAMGYDRYVAICNPLRYTVLMGRGVCVGLVAAACACGFTV
AQVITSLVFHLPFHSSNQLHHFFCDISPVLKLASHHTRSGQMAIFMLCALVLVIPLLLIV
VSYIHIISAILQ-FPSTLGRYKAFSTCASHLIIVTVHYGCASFIYLRPKSDYSSSQDALI
SVSYTILTPLFNPM-IYSLRNKEFKSALRRRLFLPPFSPLSC------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VAAML-GVNHT--FMPQFILIGFSAFPH-------------------
------------------------------------------------------------
--LQR---MLADLLSTHH-SITFVACGNQMFF-SFTFGF-THSFLLTVMGYDRYV-AICH
PLRYNVLMSPHGCACLVAWSWIGGSVM----GMVVTTAVFQLTFCGPNEIHH-FACHMPP
-LLKLACGENVPVVAKCVGLVCITVLLGCCLLILLSYAFIVSTILRIPSAEGQHKA----
-----F--------------STCASHLTV-VVVHYGFASVIYLKPKGPQ---SLEGDT--
-LMGITYTVL-TPFL----SPIIFSLRNKEL---KVA---MKK------TFLSKLSLQNS
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----DFLIIFFSFVKFKTMSINKT--LLEEFILVGFSVYP-DWQVV----LFVTFLF-LY
LLTLTGNLA-IMALTWVDHTLHT--PMYLFLSALSFSETCYT--LT--------------
I-IPK---MLVDLLAKDR-SISIPGCGLQMCF-FLGLGG-TNCIILTVMGLDRFL-AICN
PLRYPIFMTNKVCGQLVASAWIGGFFI----SLTETTLIFWGSFCGPNFIKH-FFCHMRA
-VVKLSCRN-RDITEVVVTIISVSGLLGTFLFIVLTYVFILSTVLKIPSAEGRKKA----
-----F--------------STCASHLTV-VIIHFGFASIVYLKPEAE-----EGDDT--
-LTAVPYTVV-TPFL----SPLIFTLRNKDM---KNA---LKK------VLDKKFSLTK-
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNFT--EVTEFIFLGFSSLG-KHQIT----ISGVFLT-VC
ILTLAGNII-IVTIVCIDHHLHT--PMCFFLSMLASSEMVYT--LV--------------
I-V---------LIFHNQ-RISLAGCATQMFF-FVILAI-NNCFLLTAMGYDCYV-AVCR
PLRYTVIISKGLCAQLVCGSFGI---------VLHVTAMFSLPFCGTV-VDH-FFCDIYP
-VMKLSCID-ITIDEIINYGVS---------LIFTSYVLIISFILKIASTEGWKKT----
-----F--------------ATCASHLTV-VIVHRGCSSTTYLKPKSEN---STEQDL--
-LLSVTYTII-APLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RENLT--VVSEFIFQAFSSFH-EHRLI----LFVVFLT-LY
LLTLAGNAV-IVIIISTDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-----------------------------------------------------------
-----------VCAQLGWGACTCGLLV----AIIQISSVFRLPFCDRE-VAH-YFCDIRP
-VMKLSCAD-TTVHDIINFIISSMVIVVPMGLVFISYILIISTILKIASAAGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKSKSEN---TRDEDQ--
-LISVTYTIF-TPLL----NPVVYTLRNKEV---KDA---LYR------AIAKKSLA---
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MP-GQNYS--TMSEFILFGFSGFPQQLLPV----LFLLYLL-MF
LFTLLGNLL-IMATIWIEHRLHT--PMYLFLCALSNSKILLT--VA--------------
I-TPR---MLADLLSTHR-SITFVSCAGQMFF-SFMFGF-THSFLLMAMGYDRYV-AICH
PLRYNVLMSPHDCAHLVAWTWAGGSVM----GMMVTMIVFHLTFCGSNVIHH-FACHVLS
-LLKLACGNKTSSVIMGVMLVCVTALKGCLFLIILSYVFIMAATLRIPSAEGRQKT----
-----F--------------STCVSHLTV-VVVHYSFASLIYLKPKGLH---SMYSDT--
-LMATTYTVF-TPFL----SPIIFSLRNKKL---KNA---INK------NFHRKFCLLSS
C---MPIWW----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-RKNLT--EVTEFIFLGFSSFG-KHQTT----LFVVFLT-VY
IFTLAGNII-IVTITCVDHHLHT--PMYFFLSTLASSETVYT--LV--------------
I-VPR---MLSSLVFYNQ-PISLPGCATQMFF-FVTLAI-NNCFLLTAMGYDRYV-AICA
PLRYTVIMSKRMCAGLVGGSFGTGLMM----ATLQVTAMFNLPFCGTM-VDH-FFCDIHP
-VMKLSCVD-TTVNEIINYGVSSFVILVPIGLITISYILIIHSILKIATAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSES---SVEKDL--
-LLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LRR------AVGRSVS----
-------------------------------

----------------------MEKINETKVKEFVFLGFSALASLQ--KLLFVIFLLLYL
FTLGANAVI-ISTIVLDRALHTPMFFFLSILSCSETCYTFVIVPKMLVDLLAEKKTISFL
GCAIQMSTFLFLGCSHSFLLAAMGYDRYVAICNPLHYAMLMEPGVCVRLVFAACACGFIV
SVVITSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSRLSQLIIFMLGVFVLVIPLLLIL
ISYVRIISAILQ-IPSSAGRYKAFSTCASHLIVVIVHYGCASFIYLRPKTNYSSNQDTLI
SVSYTILTPLFNPM-IYSLRNTEFKSALRRTMGQTSYPIN--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MQ-GKNFT--ELTEFIFLGFSSFG-KHQIT----LFVVFLT-VY
ILTLVANII-IVTIICIDHHLHT--PMYFFLSMLASSEMVYT--LV--------------
I-VPR---MLLSLIFHNQ-PISLAGCATQMFF-FVILAT-NNCFLLTAMGYDRYV-AICR
PLRYTVIMSNGLCAQLVCGSFGIGLTK----AVFHVTAMFNLPFCGTV-VEH-FFCDIYP
-VMKLSCID-TTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGWKKT----
-----F--------------ATCASHLTV-VIVHCGCASIAYLKPKSES---SKEKDL--
-VLSVTYTII-TPLL----NPVVYSLRNKEV---KDA---LCR------VVGRNIS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------FRFCDDLMK-RENYT--IITEFTFQGFSSFH-EHQMT----LFVVFLK-LY
ILTLAGNVI-IVTIIRMDRHLHT--PMYFFLSMLSTSETVYT--LV--------------
I-LPR---MLSSLVGRSQ-SISLAGCATQMFF-FVTFGI-TNCFLLTAMGYDRYV-AICN
PLRYTIIMNKRVCLQLVGGACSIGLVV----AVTQVSAVFRLPFCATK-VAH-FFCDIRP
-VMKLSCID-ITVNEILTLIISVLVLVVPMGLIFISYVLIISTILKIASAEGRKKA----
-----F--------------ATCASHLTV-VIVHYGCASIAYLKPKSEN---TRDEDQ--
-LISVTYTVI-TPLL----NPVVYTLRNKEV---RDA---LYR------AICRKHS----
-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MK-RQNQS--MTTEFILVGFSNQG-NLQIL----LFFVFLL-VY
LTTLMANAT-IMIVIRLDRTLHT--PMYFFLFVLSCSETCYT--LV--------------
I-VPK---MLTNLLSASQ-TISFSGCAAQLYF-FVGFAC-TNCFLIAVMGYDRYV-AICN
PLNYALVVGRATCVQLVLASGFCGFLI----SAVVNALVFSVPFCASHRINH-FFCDISP
-VIKLGCTD-TNRKEMVIFFLSILVLLVPSVLIFISYVLIVSTILKIASAEGRKKT----
-----F--------------ATCASHLTV-VVVHYGCASFIYLRPTSLY-S--SDKDR--
-LVAVTYTVI-TPLL----NPLVYALRNKEV---KVS---LSK------VLSRYSFPKTV
-------------------------------

Query Results

"ENSGT00760000119043"

ENSGT00760000119043