Query Results 

--------IMLQ-H-FIIFFLGLVVQNFCSPAETTRQ-AKRCDKKSLLTIRTQCRSCSLN
FEVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKEYLQPQCCPGHWGPD
CM-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGSSCSSVCNCVHGVCNSGVDGDGTCECYSAYTGPNCDKPI--------------
--------------------------------NPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQANFGNCPMKSTVCKYDGPGQSHCECKDH--YHNFVPGVGCSLTN
ICESNNPCHRNANCTTIAPGQTECTCQKGYVGDGSTCYGNIMERLRELNTEPGGQWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFDVNELLMDNKAAQYFVKLHIIAGQ
MNIERMNN--TDTFYTLTGKSGEIFNNDKDNQLKLKLYGGNKMVKIMQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIAPTFESNTEQTVMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYNKFRSLLE----ETNVGHALDEDGVGGPYT
IFVPSNEALNNM-DSTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPRVRSMANQ
VIQFNTTDNGQLLANGVAMEEIEVAAKNGRIYTLAGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VHWSKCPANSEPTALFTHRCVYRK--RSL---KSGCARYCNATMKIPKC
CKGFYGPDCS-QCPGGFSNPCSGNGQCADSLGGNGTCICKDGFQGSQCQFCSDP-NKYGP
QCDKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCAY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMGPCSGLT-PGGCSRNAACIKTGAGTHTCVCQQGWTGNGRDCVEIN
NCLLPGAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPITT

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ASCQFT-SGVWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1148)

CYGNAAVD--------
-------

PF02469 // ENSGT00760000119025_0_Domain_11 (1148, 1257)

-ASLQPTLSVASNLTVLVPSQQATEDMDQDEKTFWLSQSNIPALIKYHTLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHVIDK---
------------------------------------------------------------
----------

PF02469 // ENSGT00760000119025_0_Domain_12 (1331, 1401)

EEDVLRYHVVLRETLLKNDLHNGMHRETMLGFSYRLGFFLRSGQLYVNEA
PVNYTNIATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGKCGKCPQ--QPICPFGTKPLG
DE-MRKCIYTFYFMGKRSVAIGCQPKCVRTVITRECCAGFFGPQCQPCPGKAQ-NSCFGN
GICLDGINGTGVCECGVGFSGTACETCAEGKYGIHCDQ--VCPCVHGRCNQGPSGDGSCE
CDVGWRGVKCDSAITKDNCNGTCHTSANCLLDPDGTASCKCAAGFRGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRTCVCRAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRNAECTQT
GPNQAVCNCLPTYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CSLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLIKNGGCSEFAICNHTGR-ERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKDPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFLKDLAGPGPFTVFTPSSAAFDEEAQIKD--WDK
QGLIPQILRYHVIACHQLLLENLKMTPNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIIHIIDRLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKHLLITPKDTSGRILQNLTTVAINHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSNLIQD--SGLL
SMITDPIHTPVTLFWPTDQALQALPSEQQDFLFNQDN--KDKLREYLKFHVIRDSKVLAV
DLPRS-AWKTLQGSELSVTCGAGS-DIGELFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGHCDIFTTFDVSGDCGSCINTPS-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRQQ
CSLVIQL-PKCCKGYFGRDCQACPGGPETPCNNRGVCLDHYSATGECKCNTGFNGTACEL
CWPGRFGPD-CQPCGCSDHGRCDDGITGSGQCLCETGWTGRFCDT---------------
-----------------QAALPPVCTPPCSAHATCKENNTCECNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
RQSNGGCAKAAKCSQKGTKVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--ADCADLHFQDTTMG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLDSGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2564)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTDFL--------KDVLAYSNSSARGRAF-LEHLTDLSIRG

PF02469 // ENSGT00760000119025_0_Domain_27 (2564, 2664)

TLFAPQNSGLEGSETLS
GRDIEHHLSNVSMFSYSDLVNGTT----LQTRLGSQLLITSSQDPLHL------KETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTSTHPGLVIGMVLAVFLVTGAIAFAARSY
FRLNRR-TIGFQHFESEE-DIDVPALGKQQPENVSN-PMYESTT-SAPS----EPSYDPF
ADCGEQ---QLESS--DPLGAL-----

AAKSRLFLH---LLDKVLLIEIGFILHRCTKPLEAEQMKKRCDQKLLVQMETQCTPCSLN
LETRCPAGYIKITNG-TGIPDCR-YYLEIRSHSLSLPGCRHSCMKEIQQPECCQGYWGPD
CI-----------------A

PF00008 // ENSGT00760000119025_0_Domain_0 (141, 177)

CPGGAASPCNGRGHCSQGW-NGNGTCTCQKGFAGTACEKC
AEEHLFGPQCTSVCSCVHGVCNSGITGDGRCTCLSGYQGLSCDQPIA----ECKALQCPA
NSRCTTSGEDGRRLQCTCLPNYHGDGTKCEPINPCFTKVCDPNANCTYLGPNHHKCTCRE
GYRGDGQVCLPIDPCQMLYGNCPAQSTICIYDGPGKSHCECKEH--YTNFVPGKGCSMTD
ICETNNTCHKKAKCSMVAPGQITCTCQRGSVGNGFVCYGNIMERLQDLNTEAGGRWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

KL
TSALALME-NVYEWPLSSLGPFTVFVPT-NRGLKGTNIKELLNNNLKAQYFVKLHVIAGQ
LNTTSLNN--TDIIYTLTGKSGEISRGEKDNQLRIRIQGGRRKGKLLQGNIIASNGILHI
VDKAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

NMEPTFESNKEETIMSVLQDNG

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSQFASLIE----KTGLGMDLQQ--ENRPYT
VFVPSNDALSNMKAEDLDYLLSAEGSLKLVELVRYHTVSNAELEIASLISIGHIRSMAKQ
FLYFNTTSTGQVLVSGEEMEETDIVAKNGRIFTLAGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPTI--VPILPHRCDETKSQI
AMGVCASCFS-HALSPCPPDSKPIPFSKRTCI----IEGPAYPKTGCTRYCNITIKKPKC
CRGFFGPSCS-P

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSKPCSGNGQCMDGLEGNGTCICAEAFQGSL

ENSGT00760000119025_0_Linker_6_7 (828, 884)

CQFCSDP-DKYGP
QCDKKCLCIYGKCDNRIDSDGICLPGSCRKGYTGKFCDKPVVP

PF00008 // ENSGT00760000119025_0_Domain_7 (884, 972)

CEPSL-QLCHEHADCQL
SDG---------------------------------------------------AVSCVC
KSGYEGDGMT-

ENSGT00760000119025_0_Linker_7_8 (972, 978)

CSKVDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CASLY-SGGCNIHAECIQTGPGGHACACQPGWTGDGWDCSAIN
NCLLPSVSGCHENATCIYIGPGQKQQNDCKCKDGFRGNGIECTLINS

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQNGKCHRL--
------------------ATCQLEPSYGWECVCPKGYE-GDGRI

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAADELSTLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAT
AFNQWINDAQLNSVLSTTSNLTVLVPSLQAIENMDEDEKDFWMSKSNIPALLKYHLLTGA
FSFADFQNLSSSDMLPTSLQSNFLHLSKENGNLTVEGAHIVTGDIASTNGIIHVIDKVLT

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PLRS--TIMPRLLARLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QYSLANEIEAANTYTVFAPNNDAIEN
YLRDKKVATLDEDLIRYHILIDEKLLKNEMHNGMHRETMLGYSYHVGFFLHNSQLFVNDA
PISYANVATDKGIIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1485)

IQKNRCDTNHTVITLKEKCRICSQ--PSSCPPGTKEIA
GE-KKYCIFSENNMRLYTIQIGCQTKCAKTIITRECCAGFFGQQ

PF00053 // ENSGT00760000119025_0_Domain_13 (1485, 1542)

CQPCPGKAG-SACFGN
GICLDGINGSGICQCGAGFVGTACESCAEGKYGRNCDQ--V

ENSGT00760000119025_0_Linker_13_14 (1542, 1622)

CACIHGKCSSGIDGDGSCE
CNVGWRGVTCESEIKDDACNNTCHTSANCLLLSNNTAYCKCAAGFTGNGTFCT----AID
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSANAECRKTTPGNRVCVCKAGYTGDGVV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAVCNCLKGYSGDGKR

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTYINL

PF00008 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CSQNNGGCSEFAICKDTELTERTCTCKPNYIGDGF
K

ENSGT00760000119025_0_Linker_16_17 (1742, 1755)

CRGNIHKELLRNF

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

NTSKFYFHLEALSIRDTADPGPFTVFVPHTKVLNSDQRVRG--WLA
KGVMAQILRYHIVGCASLLHSDLTTVTNITSLHGDPIQISYA-QNSLYLNNKAEIISSDT
VGTNGVIHVINQILV

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PSHIQDFPPGSKRLTVTVVTMQ-VLHK--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2040)

NLKKKKKLQK--NKLL
GLINDPIHKPVTLFWPTDAAIRSLPQEQQDFLFKKSN--TDKLVQYLKFHIVRNAEILAY
QLPHSTLLKTLQGSNLSISCGDNK-EIGTLFLNDRQCKIVQRQLEFDGGIAYGIDCLLM

ENSGT00760000119025_0_Linker_18_20 (2040, 2130)

D
PSLGGRCDSFFTVDIMGYCASCFSGAK-CPPGTKPKEGIYRCTYD---SYGLRRDGCRRN
CSMVIHT-AKCCKGYFGPDCQACPGGPET

PF00053 // ENSGT00760000119025_0_Domain_20 (2130, 2174)

PCNSHGYCDDGYTGTGECHCYSGFNGTSCEL
CLPGRYGSS-CRP

ENSGT00760000119025_0_Linker_20_21 (2174, 2174)

PF07974 // ENSGT00760000119025_0_Domain_21 (2174, 2203)

CECKNNGQCEEGYSGTGRCFCETGWTGRL

ENSGT00760000119025_0_Linker_21_23 (2203, 2245)

CEN---------------
-----------------KLALPPV

PF00008 // ENSGT00760000119025_0_Domain_23 (2245, 2274)

CSPSCSVNAVCMENNTCQCKPLYNGDGIT

ENSGT00760000119025_0_Linker_23_24 (2274, 2280)

CTAADL

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCHKAANCTQLGVKIFCNCQKGYKGDGFT

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CLPINP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGFNGGCHEHAICTVIGP
DKRKCDCKNNYIGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2393)

CSVMQFPLDRCLQNNGQCHPD--ADCTDLHFQDTT

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

VGVFHLRS
PQGQYKMTYEKAKEACANESATVATYNQLLYAQKARYHLCA-AGWLDGQRVGYPTAFSSP
NCGAGYVGIVDYGRRVNLSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2519)

YREK--EVNCTCRPGYVGDGSSCSGNLLQVLM

PF02469 // ENSGT00760000119025_0_Domain_27 (2519, 2667)

SF
PTLTNFL--------EKIMAYSNSSRKGRAF-LRYLTDLSVHATLFAPNDSGLRENQTLS
GRDIEYHLSNASIVFYEDLTNGTT----LLTRLGEKLLITDNRERK-------KTETRYV
DGSAIVEWDIVASNGIIHVISEPLRAPPAPA-HLHASTGTGIFFGICLVIGVMAFIGYSY
LRFRKK-STSFQHFKSKD-EADVTSLDKPLPSNITN-PSYESSSALTPS----EPTYDLF
SDSDDQ---QLVMS--GP---------

--------AMLR-N-SIPFLLGLVVQNFCSPPGTAEQ-TKRCDKKSLLVMRTECQSCPLN
FEIDCPDGYTKVTNGSIGVRDCR-YAFVVRSYSLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCSGRGSCDEGM-EGNGSCSCQEGFGGTACETC
ADDNLFGPNCTGVCSCVHGVCNSGLDGNGTCECYSAYTGPHCDKLLPPSL-KCAALLCPE
NSRCSLSSEDETKLECKCLPNYKGDGKYCEPINPCSQNVCHPHAHCTFLGPNQHNCTCRE
GYHGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKKH--YHGFVPGVGCSVTD
I

PF00008 // ENSGT00760000119025_0_Domain_3 (362, 397)

CKSNNPCHRNANCSTIAPGQAKCTCQKGYVGDGSR

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLTT-DKGLKGFNVKELLMDNKATQYFVKLHIIAGQ
MNTERMNN--TDTFYTLTGRSGEIFNGDKDNQLKLKLDGGKKKVKIIEGNIVASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KMTPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGYALDEDGVGGPYT
VFVPSNEVLSNMKDGTLDYLLSPEGSWKLLELVRYHIVPFTQLEVATLISTLRIRTLANQ
IIQFNTTSNGQILANDVAMEELEVAAKNGRIYTLTGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--VPILPHRCDEAKSEM
KLGTCMSCSL-IYLSRCPANSEPTELFTHKCVYTGRTRNL---KSGCARYCNATVKIPKC
CKGFYGPNCN-Q

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSNPCSGNGQCIDGLSGNGTCICQDGFHGSQCQFCSDP-NKYGP
RCDQQCLCIDGTCDNRVDSDGACLPGTCREGSAGRFCHKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
NAGYEGDGSL-CSEMDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CAGLT-AGGCSRNAECIKTGVGTHTCVCQQGWTGDGRDCSEVN
NCLLPSGGGCHDNATCLYLGPG---QNECECKTGFRGNGIECEPITSCLEQTGKCHPL--
------------------AACQFT-SGVWSCVCGEGYE-GDGFLCYGSAAVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

AAA
KFNQWISNASLHPMLSAASNLTVLVPSQQAIEDMDQDEKAFWLSKSNIPALIKYHTLLGT
YGVADLQALSSSDMLATSLQGNFLHLAKADGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYLI----QYNLVNAIEAADAYTVFAPNNDAIEN
YIRQKKVTTLEEDILRYHVVLEEKLLKNDLHNGMHRESMLGFSYLLGFFLRNDQLYVNDA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-VRGKCGKCPQ--QPICPLGSKPLG
SQ-IRKCIYTIYFMGKRSVFIGCQPNCVKTVITRECCAGFFGPQCQPCPGKAE-NVCFGN
GICLDGMNGTGVCECGEGFNGTACETCTEGKYGVHCDQ--ACACVHGRCSQGPAGDGSCE
CDVGWRGVKCDFEITKDNCNGTCHTSANCLPNPDGTATCKCAAGFQ-NGTVCT----AIN
ACEISNGGCSAKADCKRTTPGRRVCVCKAGYMGDGIVCLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCHRHAECTHT
GPNQAVCNCLPRYTGDGKVCTLINTCLNRNGGCSAFAICNHTGEEERTCTCKPNYIGDGF
TCRGNIHQELPRNP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQYFFQLLEHSVRDLAGPGPFTVFAPLSAAFDEEPRIKD--WDR
QGLMPQVLRYHVVACHQLLLENLKLTPNVTSLQGESIVISVS-QDTVEINNKAKIISSDI
ISTNGVIHIIDKVLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKNLLIIPRDSAGKVLQNLTTLAMNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YSKFSNLIQD--AGLL
SLITDPIHTPVTLFWPSDQALQALPREQQDFLFNQDN--QDKLREYLKFHVIRDAKVLSV
DLPRSAAWKTLQGSKLSVQCGANS-NISELFLNSQTCRIIQRELLFDLGVAYGIDCLLI

ENSGT00760000119025_0_Linker_18_20 (2040, 2123)

D
PTLGGRCDTFTTFDISGNS--CWDQPCALPVIFKPTHPFSHSIYS-G-SVERILGW-EST
HSPSLHSPSLKVSPCHGRTPSA

PF07974 // ENSGT00760000119025_0_Domain_20 (2123, 2158)

CPGGPDAPCNNRGVCLDQYWATGECKCNTGFNGTA

ENSGT00760000119025_0_Linker_20_21 (2158, 2171)

CEL
CWPGRFGPN-

PF00008 // ENSGT00760000119025_0_Domain_21 (2171, 2203)

CQPCGCSDHGQCDEGITGSGQCLCEAGWTGRF

ENSGT00760000119025_0_Linker_21_23 (2203, 2245)

CDT---------------
-----------------QAALPPV

PF00008 // ENSGT00760000119025_0_Domain_23 (2245, 2274)

CTPPCSAHATCKENNTCECNLNYEGDGIT

ENSGT00760000119025_0_Linker_23_24 (2274, 2280)

CTVVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTKVSCSCPKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CSEVDP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGLNGGCHEHATCRMTGP
GRHKCECKSHYVGDGVD

ENSGT00760000119025_0_Linker_25_26 (2358, 2393)

CQPEQLPIDRCLQDNGQCHAD--AHCTDLHFQDTT

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2462)

VGVFHLRS
PLGQYKLTFDKAQEACANEAATMATYNQLSYAQKVGP------QWGDTLAVAFLEGSAGS
SWTGAQEDINDHKPRVSLSPRSSPISLDELDFPVSEGAEKGVNEDGLDLSHRQKPVHLER
PAPQNYLVIA---------QWEQRRWRPTRYNIRTLPPTSITTQ-SLYHSSDLT-KPLMA
GPRILEDHLNISSFWAGQVVSGVLCCLLMKIRLKPRLPDPGQNEQLPS------IETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTAAHTGLGTGIFFAVTLVLGAIALAAYSY
FRLNRR-TIGFQHFECEE-DFDVTALGKQLPENISN-PMYESAT-SAPP----EPSYDPF
MDSEDQ---LLEGS--DPLGAL-----

GGGARRFPTMLRCA--RVILLGLFLQKSCSLAAAPEQ-GNRCDKKIVLTVTTPCQPCTVR
L--PCLNGFT-----SAGVQDCRYSLC----KNK---PQHAICQKNQSQPECCPGHWGPD
CM-----------------ECPGGAKSPCSGRGNCSEGI-EGNGSCSCLEGFSGTACETC
TQDNVFGPNCTSVCKCVHGVCNNGLQGDGTCECYTGYTGPNCDTPVP----ECASLLCPE
NSRCSPQSEDRTKLECRCLPGYRANGKDCDPINPCLHLPCGPHARCNYLGPNQHSCTCGE
GYLGDGLVCLPEDPCQADFGKCPPESTVCKYDGPGKSHCECQEH--FHSFVPGVGCSMTD
LCKTKNPCHGNANCTMAAPGQTQCICPQGYVSDGFTCYGNIMERLQELDTVPRGTWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TTFISLLD-KAYAWPLSSLGPFTLLLPSSEKEPKEFNVKELLRDPEAARHFAKLHIIAGQ
MSMEQMNN--SDTFYTLSGVPGRISNRDKDNQIKLELHGGKKKVKIIEGNILASNGLIHI
LDAA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNIKPTLESDSKQTIAKLIPE--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RCSRFRALLQ----ATNLASTLDKDGDNGPYT
VFVPSNEALLSMKTDDLRYLLSPEGSKKLLELVRYHIVPSTQLEVATLVSTRQIRTMANQ
IIRFNVTANGRILANDVAMEDIEVTAKNGRMYTLGGVLIPPSI--LPILPQRCDETQSET
VQGSCVSCAV-VSHSSCPVNAVPMVSA---------IGGS---TRGSGGARDVSSQIPKC
CKGFCGPDCI-PCQGALLNSCPPNKQYVKDINGNGTCICKDGFYGSHCEFCSDR-KSYGP
QCDQKCHCVLGTCDNRVDSTGACQPRSCRPGIHGKFCDSRFLFCGPFRLHICSIYAQCRP
DSL---------------------------------------------------TLGCVC
RPGYEGNGVV-CSEKDPCANPS-RGGCSQNVS-----AFGHLCICQPGWTGNGRECVEIN
PCLLPSKGGCHSNATCLYVGPG---QVSCCAGAGAGSPGQLLS-----------------
--GNK------RSPPPPQATCQVAASGEWSCVCQEGYK-GDGFLCYGNVAVVTGSLCS--
--PPVAQN

PF02469 // ENSGT00760000119025_0_Domain_11 (1149, 1261)

ALLQPVLSASSNLTILAPSQQAVEDMNPDEKNFWLSESNIPALIKHHTLPGT
YSMEDLQSLPSPGTLATSLQGSVLPLQKVDGNVTLGGAAIINGDNMATNGVIHIISKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PERSLSGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSAFRGYIM----HYNLASVIEAADAYTVFAPNNDAIKS
YIREKKVSSLEEDTIRYHVVL-EKLLKNDLRHGLHRETLLGPSYMLGFFLRGNQLYVNEA
PINYTNAATDKGVIHGLEKVLEIQKNRCDNNETIT-IQGKCEHCQK--PPICPPGTKPLE
KR--SPCVSSFYFMGKRSVFIGCRPTCTRTVITRSCCAGFFGPQCQACPGQLG-STCFGN
GICMDGVNGTGMCACDPGFQGTACETCVDGKYGIHCDQ--ACTCVHGRCNQGPSGDGSCD
CDVGWRGVSCDSAITEDHCNGTCHTSANCLLSPDGNASCSCAAGFQGNGTVCK----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRNGGCAPEAYCKRTTPGSRVCECKADYTGDGIVCLGRGLSLACRGGGT-WASAAGT
IPHVLVGKCLPG-TGAGFCSAEINP

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLENNGGCDRNAECTHTGPNQRTCTCKQNYVGNGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1769)

CRGHIYEELPKDPQTSQYFFQLQEHKI

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RDLVGEGPFTVFAPLSAAFDREPRIKD--WDR
LGLMPQVLRYHIVACQQLLLENMKLTPNVTSLQGEQIVISVS-QDAVSINNKAKVIASNI
MNRNGVVHIIDTLLSPQNLLVTPRDASGRVLLWGAEAG---GSHLPRRSRLLGPQSSQLC
ETLTQLELDFVFLLWTGQLCHG-------------RG--R-----VPGCPAQRR-GTLLG
SWF--Q---RFQSVALAPLSGCERQGSGQLFLNDQKCRIVQRELLFDLGVAYGIDCLLIE
HSLGGHCTVFSTYDVMGDCGNCLSTPK-CPAWSKPKVTMRAAVVFRG-R------TCVWG
GVIQMRY--LCH---PGSCLAACPGGPDTPCNNRGTCLEMLSLDGQCLCNPGFNGRACEL
CLPRHFGPD-CQPCNCSAHGQCDDGISGSGQCLCDSGWTGSSCDT---------------
-----------------HTAVVPVCKPPCSVHAVCRENNTCECGLHYEGDGITCTAVDS

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAQCSQKNTTVSCSCPNGYQGDGYS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CVKIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKRKCKCKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLRCCH------TVRHQ---------TLNTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHVRS
PLGQYKLTFDTARATCASEAATVATYNQLSYAQKAGYHLCS-AGWLDSGHVAYPTAYSSR
KCGGGAVGIVDYGVRTNKSEVWDVFCYRMK--DVNCTCKAGYVGDGTSCSGNLLQVLMSS
STLNVFL--------TEVLAYSNSSARGRAF-LRRLTNLSVPSTLFVRGAP-----RGLL
G-GIGHH-LKAGAVYYEDLVNGTV----LWTPLGSPLLITTSRDELSL------NETRFV
DGRAIVLWDMFAANGVIHVISRPLKAPPAPT-SAHAGMGTGIFSAIILITGAVALAAYSY
FRLNRR-AIGFQRFESEE-DINVAALGKQRPENISN-PMYEESRSSAP-------ACDPL
AVSGRWDPGELDDS--DPLGAGA----

--------IMLQ-H-LVIFCLGFVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITSGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPQCCPGRWGPD
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH--YQNFVPGVGCSMTD
ICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKKKVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTVLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHGLDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHTCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP-NKYGP
RCNK--------------------------------------------------------
------------------------------------------------------------
------------------------------AECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECEKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ASCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVNEA
PINYTNIATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCFS--ELTCPFGTKSLG
NE-KRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGRLGDGSCD
CDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTFINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
YGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVISVS-QSTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATNNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGR-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLETGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASQDPLQP------TETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAYSY
FRINRR-TIGFQHFESEE-DINVAALGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSEEW---QLEGN--DPLGTL-----

---------------LILFFLGLVVQNFCSPPETTEQ-AKRCDKKSRLIIRTECQSCSLN
FGINCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCSGRGSCADGM-EGNGSCSCREGFGGTACETC
ADDNLFGPSCSAVCNCVHGVCNSGIDGDGTCECHSAYTGPSCDQPIP----ECAALLCPE
NSRCSPSSEDGTKLECKCLPNYKGDGKYCEPINPCLQDVCHPHARCTYLGPNQHSCTCQD
GYRGDGQVCLPVDPCQINFGNCPARSTVCKYDGPGQSHCECKEH--YRNFVPGVGCSVTD
ICESNNPCHRNANCTTIAPGQTRCTCRKGYVGDGSTCYGNIMERLRELNTEPRGRWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGTFTVLLPT-DKGLKGFNVKQLLMDNEAAQYFVKLHIIAGQ
MNTECMNN--TDTFYTLTGKSGEIFRSDKDNRLNLKLYGGKRKVKIIEGNIVASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKMAPTFKSNTEKPIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHALDEDGVDGPYT
IFVPSNEALNNMKDGTLDFLLSPEGSRKLLELVRYHIVPFTQLAVATLISTPHIRSMANQ
IIQFNTTDNGRILANGVAMEEIEVAAKNGRIYTLTGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 798)

PPSI--VPILHHQCDETKREM
KLGTCVSCSL-VYWSKCPANSEPTALFTHKCVYTGRTRSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGF

PF00008 // ENSGT00760000119025_0_Domain_6 (798, 826)

SNPCSGNGQCVDGIGGNGTCICQDGFQGSQCQFCSDP-NKYGP
QCDKKCLCIDGVCDNRIDSDGACLPGTCRAGSTGRFCHKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGSL-CSETDPCAGST-PGGCSRNAECIKTGVGTHTCVCQQGWTGDGRDCSEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPITSCLEQTGKCHPL--
------------------ATCQFT-SGIWSCVCREGYE-GDGLLCYGNVAVELSFLSAAA
V

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNQWLNNASLQPLLSATSNLTVLVPSQQAIEDMDQEEKAFWLSRSNIPALIRYHTLPGT
YGLADLQALSSSDMLATSLQGSFLHLAKADGNITIEGASIVDGDNAATNGVIHIINKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIEN
YVREKKVTSLEEDIVKYHVVLEEKLLKNDLHNGMHRETMLGFSYLLAFFLHDDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-VPGKCGKCPQ--QPICPLGTKPLV
K--TKKCIYTVYFMGKRSVFIGCQPKCVKTVITRECCAGFFGPQCQPCPGKAG-NVCFGN
GICLDGMNGTGVCECGEGFTGTACETCTEGKYGVHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGVKCDSEITKDNCNGTCHTSANCLLNPDSQPHVSCGRIFVGSFEIRE----SIN
ACEISNGGCSTKADCKRTTPGSRVCVCKEGYAGDGIVCLEINPCLENHGGCHKNAECTQT
GPNQAVCNCLPKYTGDGKICTLTNTCLTKNGGCSEFAICSHTGSEERTCTCKPNYVGDGF
TCRGNIYQELPRNPSTSQYFFQLLEH

PF02469 // ENSGT00760000119025_0_Domain_17 (1767, 1876)

SVRDLAGPGSFTVFAPLSAAFDDEPKIKD--WDK
QGVMPQVLRYHVIACHRLLLENLKLTPNATSLQGEPLVISVS-QDGVYINNKAKIISSDV
IATNGIIHIVDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLIVTPKDASGRILQNLTTVARNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSNLLQE--AGLL
SLITDPVHTPITLFWPTDQALQALPPEQQDFLFNQGN--KDKLEEYLKFHVIRDSKVSAV
DLLRSATWKTLQGSELSVKCGAGS-DIGQLFLNDQRCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFATFDISGDCGSCVSPPS-CPRGTKPKGMKQRCLYN-L-SFKRNLEGCQQQ
CILVMQL-PRCCKGYYGRDCQACPGGPDTPCNNRGVCLDQYSATGTCKCNTGFNGTACEL
CWPGRFGPD-CQPCGCSDHGECDDGVTGSGQCVCETGWTGRFCDT---------------
-----------------QTALAPVCTPPCSAHATCKENNTCECKLNYEGDGITCTVVDFC
KQNNGGCATVAKCSQKGTKVSCSCPKGYRGDGRSCTEIDPCADGLNGGCHEHATCRMTGP
GKHKCECKSHYVGTGVDCEPEQLPIDRCLQDNGQCHAD--ASCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFNKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFSSQ
NCGSGVVGIVDYGPR-NKSETWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSL
PSLTNFL--------TVCAVLERGVSERRPW-LTHLDLWPAHGTCYIALKSNDSSVKSSS
IRSLRNPFSNSSLQLLDQVI-GTK----ATNVLWS-VLAVSRSPMLPI------SENRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVAAVHTGLGAGIFFAVVLAIGAIALAAYSY
FRLNRR-SIGFQRFESEE-DISVTALGKQQPENISN-PLYDSMT-SAPP----EPSYDPF
SDSEDQ---QLESS--DPLGAL-----

--RRQHILNMIL-P-LIPLFLGFLVQNTCSPAEASGQ-AKRCDKKSFLTIWTECQACSTN
FAAKCPDGYVKITNGSVGVRDCR-YSFEIRTYSLSVPGCRHICRKDYLQPQCCPGHWGPH
CM-----------------ECPAGAASPCSGRGICDEGM-EGTGRCSCQEGFSGTACETC
AVDNVFGPNCSSVCNCVHGVCNSGLHGDGTCECFSAYKGPRCDTPIP----ECVALLCPE
NSRCSLSSKDETKLKCKCLPGYVGDGQHCTPINPCFKNICHPHASCSYLGPNRHSCSCQK
GYHGDGQVCLPVDPCQTNFGNCPTKSTMCKYDGPGQSHCECREH--YSDFVPGVGCSMIN
VCESKNPCHKNANCSTVAPGQTQCTCQKGYTGDGLTCYGNIMERLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TTFISILD-RTYGWPLRNLGPFTVLLPS-DKGLKGFDVKELLMDNEAARYFVKLHIIGGQ
MSTEQMND--TDTFYTLTGKSGEIFNRDKDNQLKLKLHGGK-MVKIIQGDIVASNGLIHV
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIEPTLLSNPQKTIMEILQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETSIGQALDEGGVGGPYT
IFVPSNEALDNMKEGTMDFLLSPKGSRKLLELVRYHIVAFIQLEVTTLISTSHIRSMANQ
IIQFNISQNGQILANDVAVQETGIVAKNGRIYTLAGVLVPPSI--IPIIPHRCDETKKEM
IPGTCVSCSL-VRLSKCPADSEPTALFTHKCVYSSRTRNM---KSGCARYCNATIKIPQC
CSGFFGPDCT-PCPGGFLNPCSGNGKCRDGLSGNGTCICDDGFQGSKCQFCSNP-NRYGP
RCNKTCLCAHGACDNRVDSDGACLSGTCREGTAGKFCNKQTSTCGPYV-YFCHIHATCKY
YNG---------------------------------------------------TASCVC
NEGYEGDGTL-CSKKDPCMGSTSRGGCSQNAECIPTGPGTHICVCQQGWTGDGRDCVEIN
NCLLPGTGGCHDNATCLYLGPG---QNECECKKGFRGNGIDCEPVITCLEQAEKCHPL--
------------------ASCQFASSGVWSCVCQEGYE-GNGLLCYGNVFMELSLLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSMLSATLNFTVLVPSQQAIEDMDQNEKTFWLSWNNIPALIKYHTLLGT
YGVSDLQTLSSSHRLATSLQGSFLHLDKANGNITIEGASIVDGDNAATNGVIHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSVFRGYII----QYNLANAIEAADTYTVFAPNNEAIEN
YIREKKVTTLEEDILRYHVILGEKLLKNDLHNGMHRETMMGFSYLLGFFLHNDQLYVNEV
PINYTNVATDKGVIHGLGKVLEIQKNRCDKNDTTI-VRGMCGRCPQ--QAICPLGTKPLG
SNFILKCIYTIYFMGKRSAFIGCQPKCVRTVITRACCAGFFGPQCQACPGKGQ-NVCSGN
GFCLDGVNGTGTCECEQGFNGTACETCTEGKYGVHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGVNCDSEITKDNCNGTCHTSANCLLNPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEVSNGGCSVQAVCKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLPKYTGDGKT

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPLAICTHTGQDQRICTCKQNYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIYGELPKNPTTSQYFFQLQQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELTGPGPFTVFAPSSASFNQEPRIKD--WDQ
QGLMSQILRYHVVACQQLLLEDLKVTTNAMTLQGEPISISVS-QDTIYINNKAKVLSSDI
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQHLLVTPKDASGRVLQNLTTVAMNNG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2038)

-YTRFSKLIQD--SGLL
SVITDHIHIPVTLFWPTDKALQALPLEQQNFLFHQDN--KDMLKEYLKFHVIRDTRALAS
DLPRSASWKTLQGSELSVKCGTGS-DIGELFLNGQMCRIVQRGLLFDLGVAYGIDCLLTD
PTLGGRCDTFTTFNVSGDCGSCVTIPR-CPRWSKPKGLKQRCLYSPV-PFGRSLEGCQQL
CTLVIPI-PRCCKGYFLPHCQACPGGPDTPCNNRGVCLDQYSATGQCQCNTGFNGTPL--
-----------ASCGCSEHGQCDEGITGSGQCLCEAGWTGRFCDT---------------
-----------------LTVVFPVCIPPCSVHATCMENNTCVCNLNYEGDGIMCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GRHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHPD--ASCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAASMATYNQLSYAQKASYHLCS-AGWLENGRVGYPTTYASP
KCGSNIVGIVDYGIRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKAGYVGDGFSCNGNLLQVLMSL
SSLTNFL--------EEVLAYSNSSARGQAF-LKHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

RGTLFVPQNSGLLENKTLS
GRDIEHHLTNVSVSFYNDLVNGTV----LRTRLGSQLLITSSQDQLHQ-------ETRFV
DGRAILQWDIIASNGLIHIISEPLEAPPMTATPAHTGLGTGIVCAVILVTGAIGLAVYSY
FRLNQR-TIGFRHFESEE-DINVLAFGKQQAENISN-PVYESSM-PAPP----ETSGDPF
TDSEEQ---EEESS--DPLGAQRS---

---------MLQ-N-LILFLLGFVVHNSCSPPETTDQ-AKRCDKKSLLTIRTECQSCSVN
LGIQCPDGYTKVTNGSVGVRDCR-YIFEIRKYSLSLPGCRHICRKDYVQPQCCPGHWGPD
CM-----------------ECPGGASSPCSGRGICAEGM-EGNGTCSCQDGFGGTACETC
AEDNLFGPSCSAVCSCVHGVCNSGREGDGSCECYSAYTGPNCDKPVP----ECAALLCPE
NSRCSPSSQDETKLECKCLPNYRGDGHYCEPINPCLQAICHPHAHCTYLGPNRHSCTCQE
GYHGDGQVCLPVDPCQTRYGNCPTESTVCIYDGPGQSHCECKEH--YHNYVPGVGCSIIN
VCESNNPCHRNANCTTIAPGQPKCTCQKGYVGDGSTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFLSLLD-KAYAWPLSELGPFTVLLPT-DKGLKGLNIKELLMDKEAAQYFVKLHIIAGQ
MNTQRMNN--TDTFYTLTGKSGEIFNGDNDNQLKLKLYGGKNNVQIIQGDIVASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKMAPTFESNTEETIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETSVGHALDEDGTGGPYT
IFVPSNEALNNMKDGTLHYLLSPEGSRKLLELVRYHIVPFTQLEVATLIATPHIRTLANQ
IIQFNTTSNGQILANDVAIEETEIIAKNGRIYTLTGVLIPPSI--VPILPHRCDESKREM
KLGTCVSCSL-VYWSKCPANSEPTTLFTHRCVYNGRVRSL---KSGCARYCNATVQIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCVDGLNGNGTCVCQDGFQGSQCQFCSDP-NKYGP
RCDKKCLCISGTCNNRIDSDGACLDGTCREGSAGRFCHKQTSTCGPYI-QFCHIHATCEY
SNG---------------------------------------------------IASCVC
KPGYKGDGSL-CSEMDPCAEIT-RGGCSRNAECIRTGLGTHTCVCQQGWTGDGRDCSEIN
HCLLPGAGGCHANATCLYVGPG---QNECECKQGFRGNGFDCEAITSCWEQTGQCHPL--
------------------ATCQLTSSGLWSCVCQEGYE-GDGHLCYGNAAVELSFLSAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

T
VFNQWINNASLQPMLSAASNLTVLVPSQQAIEDMDQDEKTFWLSKSNIPVLIKYHMLLGT
YRVADLQALSSSDMLATSLPGNFLHLVKADETVTIEGASVIDGDNIATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTVSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

NYSIFRGYII----QYNLASAIEAASAYTVFAPNNDAIEN
YIREKKVTTLEEDIIRYHVILEEKLLKNDLHQGMHRETMRGSSYLLGFFLHDDQLYVNEA
PINYTNAATDKGVIHGLGKVLEVQKNRCDNNDTTI-VRGKCGKCLQ--QPVCPVGTKQLG
EE-MRRCIYTIYFMGKRSLFIGCQAKCVKTIITRECCAGFFGAQCQPCPGRAE-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCVEGKYGPHCDQ--ECSCVHGRCNQGPSGDGSCE
CDVGWRGVSCDTEITKDDCNGICHTSANCLLNPDGTASCKCTAGFQGNGTVCT----AIN
ACETSNGGCSTKADCRRTTPGSRRCVCRAGYTGDGIVCLEINPCLENNGGCHKNAECTQT
GPNQAVCNCLPKYTGDGKVCTLINTCLTKNGGCSEFAICNHTGLEERTCTCKPNYIGDGF
TCRGNIYQELPKNPKTSQYFFQLLEH

PF02469 // ENSGT00760000119025_0_Domain_17 (1767, 1876)

SVRDLSGPGPFTVFAPLSAAFDEEPQIKD--WDK
QGLMPQVLRYHVIACHQLLLENLKLIPNATSLQGESIVISVS-QDTVYINNKAKIISSDI
INTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLFTPKDASGRIVQNLTTVATNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSNLLQD--VGLL
GIITDPIHTPVTLFWPSDQALQALPPEQQDFLFNQDN--KDKLKEYLKFHVIRDSKILAV
DLPRATAWKTLQGSELGVTCGAGS-DIGELFLNDQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFATYNFSGDCWSCANTPS-CPRWSKPKGVKQKCRYN-M-SFKGYLEGCREQ
CTMVIRL-PRCCKGYFGRDCQACPGGADAPCSNRGVCLDQYSGIGECRCNTGFNGTACEL
CLPGRFGPD-CQPCGCSAHGQCDDGPTGSGQCFCETGWTGRFCDT---------------
-----------------QTALPPVCTPSCSAHATCKENNTCECNLNYEGDGITCTVVDFC
KQNNGGCAKVARCSQKGTKVSCSCLKGYKGDGRSCKEIDPCADGLNGGCHEHATCKMTGP
GKHKCECKSHYVGDGTDCEPEQLPIDRCLQDNGQCHAD--ADCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAKEACANEAASMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAYASQ
NCGSGVVGIIDYGQRNNKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNRSARGRAF-RKLLTDLSIRSTLFVPQNSGLGENETLS
GRDIEHHLANVSIFFYNDLVNGTV----LQTKLGSQLLITSSQDQQQP-------ETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVAAVHMGMGTGIFFATALVFGAAALAAYSY
FRLNRR-TAGFQHFESEE-DINVAALGKQQPENIPN-PLYESTP-SAPQ----EPSCDYF
MDAEDQ---QLDNT--DPLGAL-----

-RRSEYFLTMLQ-S-IILFFLGLVVQNLCSLSETAEQ-GKRCDKKSLVTIRTECQSCLVT
FGIKCPDGYTKITNGTVGIRDCR-YTFEVRAYSLFLPGCRHICRRDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCSGRGRCAEGM-EGNGSCLCQEGFSGTACEIC
AADNVFGPSCSAVCSCVHGVCNSGIHGDGTCECYSGYTGRNCDEPIP----ECAALLCPE
NSRCSPSSKEEMKLECKCLPNYKGDGKHCEPINPCSQNICHPHARCTYLGPNQHRCTCQE
GYRGDGHVCLPVDPCQVNFGNCPTESTVCRYNGPGQAYCECKQH--YHNFVPGVGCSMID
LCESNNPCHTHADCITIAPGQTKCTCRKGYIGDGSTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVKEFLLDSNAAQYFVKLHIIAGQ
MSTEQMNN--TDTFYTLTGKSGEIFSEDKDNQLKLKLYEGKKKVKIIQGNILASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKVVPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALNEDGVGGPYT
VFVPSDEALNNMKDGTLDYLLSSEGSRKLLELIRYHIVPFTQLEVATLISTPHIRSMANQ
IIRFNTTNEGQILVNGMALEEMEVAAKNGRIYTLRGVLIPPSI--IPILPHRCDETKREM
RLGTCVSCSM-VYWSKCPADSEPTTLFVHKCIYPGRIRSL---KNGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLDGNGTCVCQDGFRGSRCQFCSDP-SKYGP
RCDKTCPCIFGTCDNRIDSDGACLPGTCRNGSAGRFCHKQTSVCGPYV-QFCHIHATCEY
SDG---------------------------------------------------TASCVC
KPGYEGDGSF-CVEMDPCSGST-PGGCSRYAECIRTGRDTHTCVCRQGWTGDGRDCSEIN
PCLLPSAGGCHHNATCLYVGPG---QNECECKKGFRGNGIDCDPITSCLEQTEKCHPL--
------------------ATCQLTSSGIWSCVCQEGYE-GDGLLCYGNAAVELSFLSAAA
V

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNQWINNASLQHLLSTTSNLTVLVPSRQAIADMDQEEKAFWLTKSNIPILIKYHMLLGT
YGVADLQALSPSDMLATSLQGNFLHLVKADGNITIGGASVIDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDEMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSSFRGYII----QYNLATAIEAADAYTVFAPNNDAIES
YIREKKVTTLEEDILRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLRDDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDINDTTI-VRGKCGKCPQ--APICPFGTKPLG
QE-TRRCLYTIYFMGRRSPVFGCQPKCVKTVITRECCAGYFGPQCQPCPGKPE-NVCFGN
GICLDGANGTGACECGRGFSGTACETCAEGKYGVHCDQ--ECTCVHGRCSQGPLGDGACD
CDVGWRGVKCDSEITKDNCNGTCHTSANCLLNPDGTALCKCAAGFQGNGTVCT----AIN
ACEISNGGCSAKAICKRTTPGSRVCVCKAGYTGDGIVCIEINPCLENHGGCHRHAECTQT
GPNQAVCNCLPKYTGDGKVCTLINVCLTNNGGCSEFAICNHTGQDERTCTCKPNYIGDGF
TCRGNIHQELPKNPKTSQFYFQLLEHS

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1848)

VRDLIGPGPFTVLAPLSAAFDEESQIKD--WDK
GGLMPQILRYHVIACHQLLLENLKLTPNATSLQGESLVISVS-QVGE

ENSGT00760000119025_0_Linker_17_18 (1848, 1905)

ATSETSSQWTEKT
LSTFSLLFSVGLVYNLQSLLL---SSPHFIQQNLTTVAMNHG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YGKFSNLIQD--SGLL
SVITNPIHTPVTLFWPSDQALQALPREQQDFLFNQDN--QDKLKEYLKFHVIRDAKVLAV
DLPRSATWKTLQGSELSVKCGAGS-DIGDLFLNSQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDVSGSCGNCISTPS-CPKWTKPKGQKRKCLYD-L-PFKRNLEGCRQL
CTLVIQL-PKCCKGYFWPDCQACPGGPDTPCNNRGVCLDQYSPSRQCKCNSGFNGTACEL
CWPGRFGPD-CQPCGCSDHGQCDDGITGSGECLCETGWTGRFCDA---------------
-----------------QTALPPMCMPPCSAHATCKTNNTCECNLNYEGDGITCTVVDFC
KQNNGGCAKVAKCSQKGTKVSCSCQKGYQGDGHSCTAIDPCADGLNGRCHEHATCKMTGP
GKHKCECKSHYVGDGLDCEPEQLPLDRCLQDNGQCHAN--ADCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAREACAQEAATMATYNQLSYAQKAKYHLCS-AGWLDSGRVAYPTSYASQ
NCGSGVVGIVDYGPRNNKSEMWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------KEVLAYSNSSARGRAF-LKHLTDLSIRSTLFVPQNSGLGENETLS
GRDIEHHLSNISIFFYNDLVNGTI----LHTRLGSQLLITSSQDQRQL-----INTTRFV
DGRAILQWDIFASNGIIHVISKPLKAPS--GTSGHTGLGTGVFFAIILVIGAIALAAYSY
FRLNRR-TIGFQHFESEE-DIDVAALGKQQPENISN-PMYESTT-SATP----EPSYDPF
TDPGDQ---QLDSS--DPLGAL-----

--------IMLQ-H-LILFFLGIVIRNVCSLAETTGQ-AKRCDQKSLLIIRTECQSCPLN
FGVKCPDGYTKITNGSVGVRDCR-YTLEIRTYSLSVPGCRHICRKDYVQPQCCPGHWGPD
CM-----------------ECPGGAGSPCSGRGSCAEGM-EGNGSCSCQEGFGGTACETC
ADDNLFGPNCSAXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXIPECATLLCPE
NSRCSPSSEDKTKLECKCLPNYKGNGKYCEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHCECKEH--YHNFVPGVGCTMTN
ICESNNPCHRNANCTTIAPGQTKCTCQKGYVGDGSMCYGNIMERLRELNSEPRGQWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

ML
TSFISLLD-KAYAWPLSNLGPFPV-LPT-DKGLKGFNIKELLMDNEAARYFVKLHIIAGQ
MNTKHMNN--TDTFYTLTGQSGEIFNSDKDNQLKLKLYEGKKKVKI-QGNIIASNGLLHI
LDRPMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

QVVPTFASNTEKTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNMGHALDKDGIGGPYT
IFVPSNEALNNMKDGTLDYLLSPEXXXXXXELVRYHIVPFTQLEVATLISTPHIRSMANQ
IIRFNTTDNGRILANDVAMEEIEVAAQNGRIYTLSGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--VPILPHRCDEAKREM
KLXXXXXXXX-XXXXXXXXXXXXXALFTHRCVYTGRIRSL---KSGCARYCNATVKIPQC
CKGFYGPDCN-Q

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFLNPCSGNGQCTDGLSGNGTCICEDGFQGSQCQFCSDP-NKYGP
RCDKKCPCIHGTCNNRIDSDGA-LAGTCRD-SAGRFCDKQTSVXXXYV-QFCHIHATCEY
SNGTAXXXXXXXXXXXXX------------------------------------------
---------X-XXXXXXXXXXX-XXXXXXXAECIKTGTGTHTCVCQPGWTGNGRDCTEIN
NCLLPSAGGCHDNATCLYVGPG---QSECECKKGFRGNXXXXXXXXXXXXXXXXXXXX--
------------------ATCRFT-SGVWSCVCQEGYE-GDGLLCYGNAAVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAA
IFNQWINNASLQPMLSTTSNLTILVPSQQAIADMDQDEKSFWLSKSKIPALLKYHMLLGT
HGVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1330)

DYSIFRGYII----QYNLANVIEAADAYTVFAPSNNAIQN
YVKEKKVTTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXGKCVDCSL--KSTCPIGTKPLG
NE-TRKCIYTTYFMGMRSVVIGCQSKCVKSVITRECCAGFFG-LCQPCPGKAQ-DVCFGN
-ICLD-LNGTGVCECGGFSTVWEC----TEQYGAHCD---VCPCVHGRCNQGPSGDGSCE
CEVGWRGVKCDSAITKDNCNGTCHTSANCLLNPDGTASCRCAAGFQGNGTVCT----AIN
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAQADCKRTTPGSRVCLCKAGYTGDGII

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENH-GCSKNAECTQT
GP-QAVCNCLPTYTGDGKVCILIDTCLTKNGGCSQFAICNHTEQGERTCTCKPNYIGDGF
TCRGNIYQELPKNP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQYFFQLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXMKD--WDK
LNVIPQVLRYHVIACHQLLLENLKLTPNATSLQGEPLVISVS-QDTVYINNKAKIISSDI
ISSNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_19 (1876, 1977)

PKNLLVTPKDASGKIAXXXXXXXXXXX--XXXXXXXXXX--XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_19 (1977, 2040)

VLAV
DLPRSAAWKTLQGSELSVKCGAGS-DIGELFLNGQTCRIVQRGLLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDVSGDCGSCFYTPS-CPKWSKPKGEKQKCRYNLS-SFRRNMEGCRQL
CNLVIQV-PRCCKGYFGPDCQXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXCGCSDHGQCDDGITGSGQCFCETGWTGRSCDTQTXXXXXXXXXX---
-----------------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXVDFC
KQNNGGCAKVAKCSQKDTKVSCSCQKGYKGDGYSCTEIDL

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGLNGGCHEHATCRMTGP
GKRTCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2394)

CEPEQLPLDRCLQDNGQCHAD--ADCTDLHFQDSTL

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGRYKLTFDKAREACANESATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAYSSQ
TCGAGVVGIIDYGTRLNKSEMWDVFCYRMK--DVNCSCKVGYVGDGFSCNGNLLQVLMSS
PSLTNFLMXXXXXXXX---------XXXXXXXXXXLTDLSIRI--LFVENSGLG-NETLS
GRDIEHHLASVSIFFYNDLVNGTI----LQTRLGSQLLITSSQDQPQL-----XXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXPSTHAGLGTGIFFAIILVIGAITLAAYSY
FRLNRR-TFGFQRFESEE-DIDVTALGKQKPDNISN-PIYESTT-SAPP----EPSYDPF
TDSE-Q---QLESS--DPLGAL-----

QSGSRHFLVMLQ-H-FLIFFLALVVQNFCSPAESTEQ-AKRCDKKSLLTIRTQCKSCTYN
FQVKCPDGYTKITNGSIGVRDCR-YSFELRTYSLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGAASPCNGRGSCAEGM-EGNGTCSCQDGFGGTACETC
ADDSLFGPSCSTVCNCVHGVCNNGPDGDGTCECYSAYTGPNCDKPIP----KCAALLCPE
NSRCSPSSEDETKLECKCLPNYQQDGKHCQPINPCLQKVCHPRALCTYLGPNQHSCACQE
GYHGDGQVCLPVDPCQTSFGNCPITSTVCKYDGPGQSHCECKDH--YHGFVPGVGCTLTN
ICESNNPCHRNANCTTVAPGQTECTCQKGYVGDGSVCYGNIMERLRELNTEPGGQWQGR

PF02469 // ENSGT00760000119025_0_Domain_4 (420, 545)

L
TFFITLLD-KAYAWPLSYLGPFTVLLPT-DNGLKGFNVKELLMNSGAAQFFVKLHIIAGQ
MSTKQMNH--THTFYTVTGQSGEISNEDKDNQLKLRLYGSQKTVKIIQGDIVASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIEPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALGEDGVGGPYT
IFVPSNEALNKM-GSTLHYLLSPEGSRKLLELVRYHIVPFTQLEVATLVSAPRIRSMANQ
IIQFNTASNGQILANDVAIEETEVAAKNGRIYTLAGVLIPPSI--VPILPHRCDETRQEM
KLGTCESCSL-RSRSKCPANSYPVPLFTQRCVYRSIYRSL---KTGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGRRGNGTCICEDGFQGSQCQFCSDP-NKYGP
RCGKKCLCVHGTCDNRIDSDGACLTGTCRDSSAGRFCDKQTSACGPYI-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGVV-CSKMEPCMGLT-PGSCSRNAECIRTGLGTHTCVCQQGWTGNGRDCAEIN
NCLLPGAGGCHENATCLYVGPG---QNECECKKGFQGNGIDCEPITSCLGQIERCHPL--
------------------ASCQFT-SGIWSCVCQEGYE-GDGLLCYGNVAVEMSFLAEAA
L

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNQWIKNASLQPTLSVASNLTVLVPSRQATEDMDQDKKSFWLSRSNIPALVKYHTLLGK
YTVADLQTLSSSDLLATSLQGSFLHLAKVDGNITIEGASIVDGDNVATNGVIHIISKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGVTGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLASAIEAANAYTVFAPNNNAIEN
YTREKKISTLEEDILRYHVVLEDKLLKNDLHNGMHRETMLGFSFLLGFFVHNEQLYVNEA
PVNYTNVATDKGVIHGLGKVLEIQKNRCDNNETII-VRGKCGKCPQ--LPVCPLGTKPLG
NE-TTKCIYTIYFLGKRSVFIGCQPKCVKTVITRECCAGFFGPQCQACPGKAQ-NACLGN
GICLDGVNGTGMCECGAGFSGTACETCAEGKYGIHCDQ--ACPCVHGKCNQGPSGDGSCE
CDVGWRGVKCDNEITTDNCNGTCHTSANCLPNPDGTGSCKCAAGFQGNGTVCT----AIN
ACEISNGGCSAKADCKRTTPGSRTCVCKAGYTGDGIVCLEINPCLENHGGCDRNAECTQT
GPNQAVCNCLPLYTGDGKVCTLINVCLTKNGGCSEFAICSHTSKEGRTCTCKPNYIGDGL
TCRGSIYQELPKNPKTSQYFFQLQEHS

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1876)

LKDLVGPGPFTVFAPLSAAFDEEAQIKN--WDK
QGLMSQVLRYHMVSCHQLLLENLKMTPNVTSLQGEPIFISVS-QGTVYLNNKAMIISSDI
ISTNGIIHIIDRVLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PKNLVITPKDASGRILQNLTTLAINQG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YLKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDHALQGLPTEQQDFLFSEEN--KDKLREYLKFHVIRDSEVLAV
DLPRS-VWRTLEGSELNVKCGTAS-NIGELFLNGQTCRIVQRELLFDLGVAYGIDCLLMD
PTLGGRCDVYSAFDVSGNCGSCINTPS-CPGWSKPKGMKQKCVYH-L-SFKRNLEGCQQQ
CSLVLRI-PGCCKGYFGPNCQACPGGPDTPCNNQGVCLDQYSALGKCKCNTGFNGTACEL
CWPGRFGPD-CQPCSCSEHGQCDDGITGSGQCLCETGWTGPFCNT---------------
-----------------QAVLPPVCTPPCSAHATCKENNTCECDLNYEGDGITCTVVDFC
SQNNGGCAKAAKCSQKGVKVSCSCQKGYTGDGHICTEIDPCADGLNGGCHEHATCKMTGP
GKHRCACKNHYVGDGLDCEPEQLPIDRCLQDNGQCHAD--ADCADLHFQDATV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAREACAKEAATVATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
KCGSGVVGIVDYGIRANKSEMWDVFCYRIK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTDFL--------KEVLAYSNSSARGRAF-LDHLTDLSIRSTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LHTRLGSQLLITSSQDPLHL------KETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPVPVTSTHTSLTIGMGFVVTLAIGVIAYSVY-Y
FRRNQT-PIRFQHFESEE-DITAL----DKPETISN-LMYESTT-SAPP----EPSYHPF
VDSDEQ---QLEGS--DPLGAL-----

AQRKQYFLIMLQ-N-LLILVLGLAVQSVCSPTETTRQ-AKRCDKKSTLTMRTECQSCSLL
FGKKCPDGYITVTDISLGVRDCS-YTFQVKTYTFSLPGCRHICKKDYLQPHCCPGHWGPD
CM-----------------ASPGPAKCPETGQPCRARQLAGSSGKCTCQKGFGGTACETC
ADDNLFGPNCSRVCKCVHGVCNSGINGNGTCECYSAYTGPNCDQPIP----ECASLLCPE
NSRCSPSSKNETKLECRCLPNFKGDGKYCEPINPCLQKVCHPHAHCTYLGPNRHSCTCQE
GYSGDGQVCLPIDPCQVNFGNCPTKTTVCKYDGPGQSHCECKEH--YHNFVPGVGCSMTD
ICKSNNPCHKNAKCATIAPGETECTCPKGYVGNGLMCYGNIMMRLRELNIEPGGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLVPT-DEGLKGFNVKELLTDNKAALYFLKLHIIAGQ
STTKHLNY--TDIFYTLTGMSGEIFNRDADNQLKLKLNGGQKKVKIIQGDLVASNGLLHI
IDSA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

LDKMAPTFDSNMQKTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLK----ETNVGRALDEDGVGGPYT
IFVPSNEALDNMKNGTLDYLLSPEGSRKLLELIRYHIVPSIKLQVATLISTLQVRSMANQ
MIYFNITKNGQILANNVAMKEVDVNAKNGRIYTLAGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 798)

PPSI--VPILPHRCDATKMEI
KLGTCLSCSR-VHWSICPANSEPTVLSTHKCIYTTKTKSL---RRGCAKFCNATVKVPKC
CKGFFGPDCN-PCPGGF

PF00008 // ENSGT00760000119025_0_Domain_6 (798, 826)

SNPCSGNGECMDGLSGKGTCICADGFKGSQCQFCSDP-QKHGP
RCNQKCPCVHGTCDNRIDSDGACLSGTCREGSAGKFCDKQTSACGPYM-QFCHIHATCEH
SNG---------------------------------------------------TASCIC
KAGYEGDGVL-CSEMDPCTGST-PGVCSPNAECIKTGSGNHTCVCQQGWTGNGRDCSEIN
NCLLPSTGGCHSNATCLYVGPG---QNECECKKGFRGNGIDCQPISSCLEHPGKCHPW--
------------------ATCQFTSSGIWSCVCQEGYE-GDGLLCYGNTAEELSILSKAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFNQWINEGSLQPMLSATANLTLLIPSQQAVENMDQNEKTFWLTKSNIPALTKYHTLIGV
YSMADLRNLSSSDMLKTSLPGNFLHLKNVDGNITIEGASIVDGDNVATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTSSLPNLLARLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANAIEAADAYTVFAPNNEAIEN
YVREKKVTSLEEGTLRYHVVLKEKLLKNDLHNGMHRETMLGFSYFLGFFLHNDQLYVNEV
PINYTNVATDKGVIHGLGKVLEIQKNRCDTNNTTT-IKGRCGRCPQ--IPICPPGTKPS-
DE-ITKCIYTLYFMGKRSVFLGCRSICVKTVITRECCAGFFGPQCQPCPGRAG-NVCFGN
GICLDGANGTGVCECGKGFSGTACETCTEGRYGMHCDQ--ACSCVHGKCNQGPMGDGSCE
CDVGWRGVTCDSEITEDNCKGTCHTSANCLLSPNGTASCKCAAGFQGNGTVCT----AID
ACRVSNGGCSTKADCKRTTPGSRVCVCKAGYTGDGIVCLEINPCLENNGGCDKNAECTQT
GPNQAVCNCLPTHTGDGKTCTFINMCLTKNGGCSPFAICNHTGE-ERTCTCKPNYIGDGF
TCRGNIYQELPKNPKTSQYFFEMEEHSVRD

PF02469 // ENSGT00760000119025_0_Domain_17 (1771, 1876)

LLGPGPFTVFAPLSAAFDEEPQIVG--WNE
QGLMSQIIRYHIVACHQLLLENLKQTPNVTSLQGESIVLSVS-QDTVYLNNKAKIIFSDT
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLIITPKDVSGRILQNLTTVALNQG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YNKVSSLIQD--AGLL
SVITDPIHTPVTLFWPTDQAFQALPTQQQDFLFSQDN--KDKLKEYLKFHVIRDSKVLAV
DLPRSAAWKTLQGSDLSVKCGAGS-DIGELFLNDQRCRIVQRGLLFDLGVAYGIDCVLID
PTLGGHCDTFTTFNVSGDCGSCVNTPR-CPARSKPQGVKQKCFFS-L-PFMRKVEGCRQQ
CTMVMQL-PKCCKGYFGLDCQACPGGPDNPCSNRGVCLDDYAATGECKCNMGFNGTACEL
CWPGRFGPD-CQPCGCSDHGQCDDGITGSGQCLCETGWTGHFCDT---------------
-----------------QAVLTPVCTPPCSTHAVCKENNTCECNLNYEGDGFTCTVVNFC
KQNNGGCAKVAKCSQKGTVVSCGCPKGYDGDGRSCTAVDPCADGLNGGCHEHATCKMTGP
GKHRCVCKSHYVGDGLDCEPEQLPIDRCLQDNGQCHAD--ADCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAKETCANEAATIATYSQLSYAQKAKYHLCS-AGWLESGHVAYPTAYASQ
SCGSGFVGIVDYGVRNNKSETWDVFCYRMK--DVNCTCKEGYVGDGLSCSGNMLQVLMSS
PSLKNFL--------TEVLAYSNSSTRGQAF-LKHLTDLSIRGTLFVPENSGLGGNETLS
GRDIEHHLASVSILFYNDLVNGTV----LQTRLGSKLLITSSQDQLQT------KETRFV
SGRAILQWDIFASNGILHVISGPLKAPPAPVASAHTGLGTGIFFTVVLVIGAIALAAYSY
FRLNRR-TIGFQHFESEE-DINVEALGKQQPENLSN-PMYESTT-STPP----EPSYDPF
MDSTEL---QLDSN--DPLGGL-----

--RSQHFLSMLL-P-LIPLFLGLLVQNTCSPAEA-----KRCDKKSFLTIRTECQACSAN
FAAKCPDGYIKITNGSVGVRDCR-YSFEIRTYSLSVPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPAGAASPCNGRGICDEGM-EGTGSCSCQAGFRGTACENC
AADNVFGPNCSSVCSCVHGVCNSGLHGDGTCECFSAYRGPRCDTPIP----ECAALLCPE
NSRCSLSSR-ETKLKCKCLPGYEGDGQHCTPINPCLKNICHPHASCSYLGPNRHSCSCQK
GYHGDGQVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKEH--YSNFVPGVGCSMTN
ICESSNPCHKNANCSTIAPGQTQCTCQKGYTGDGVTCYGNIMERLRELNTEPRGAWQGR

PF02469 // ENSGT00760000119025_0_Domain_4 (420, 545)

L
TSFISILD-RTYGWPLSNLGPFTVLLPS-DKGLKGFDVKELLMDNEAARYFVKLHIIGGQ
MSTEQMND--TDTFYTLTGNSGEIFNRDKDNQLKLKLHGGK-MVKIIQGDIVASNGLIHF
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKTEPTLKSNLQQTIMEILQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYNKFRSLLE----ETSVGQALDEGGVGGPYT
IFVPSNKALDNMKADTIDFLRSPEGSRKLLELVRYHIVAFIQLEVTTLISTPHIRTMANQ
IIQFNITRNGQILVNDVAVEETGIAAKNGRIYTLAGVLVPPSI--VPILPHRCDETKREM
ILGMLGCIQ--QCF---HPLAFFQTLFTHNCVYKSRAWNL---KSGCARYCNATTKIPKC
CSGFFGPDCN-PCPGGFLNPCSGNGKCTDGLRGNGTCVCEDGFQGSKCQFCSNP-NRYGP
RCNRTTVPRHIQLLPSR---------LHREH----W-VSRPD----------------FE
PPL---------------------------------------------------LHSCVC
NEGYEGDGTL-CSKKAPCVGSTSRGGCSQNAECIQTGPGTHVCVCQQGWTGNGRDCVEIN
NCLLPGTGGCHDNATCLHVGPG---QNECECKKGFRGNGIDCEPVFTCLEQAEKCHPL--
------------------ATCQSASSGVWSCVCQEGYE-GNGLLCYGNVFMELSLLSEAA
VFYQWINNASLQSMLSATSNLTVLVPSQQAIEDMDQNEKTFWLSWNNIPALIKWVSFTLF
FMLCNWHQCEH---------SLFQCREDASGNP--YLTSIVDGDNAATNGVIHIINKVLI
PQRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADTYTVFAPNNVAIKN
YIREKKVTTLEEDILRYHVVPGEKLLKNGLHNGMHRETMLGFSYLLGFFLHNDQLYVNEV
PINYTNVATDKGVIHGLGKVLEIQKNRCDKNDTTI-VKGLCGRCPQ--QAICPLGTKPLD
ET--RKCIYTIYFMGKRSAFIGCQPKCVRTVITRACCAGFFGPQCQACPGKGQ-SVCSGN
GFCLDGVNGTGTCECEQGFNGTACETCTEGKYGIHCDQ--ACPCVHGRCNQGPSGDGSCD
CGVGWRGVNCDSEIKKDSCNGTCHTSANCLLDPDGKASCRCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAQAVCKRTIPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLPKYTGDGKA

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPLAICTHTGQDQRTCTCKQNYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1769)

CRGSIYGELPKNPTTSQYFFQLQEHDV

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RELAGPGPFTVFAPSSASFNQEPRIKD--WDQ
QGLMPQVLRYHVVACQQLLLEDLKVTTSVVTLQGEPISISVS-QDIIYINNKAQVLSSDI
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQHLLVTPKDASGRVLQNLTTVAMNNG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2038)

-YTRFSKLIQD--SGLL
SVITDHIHIPVTLFWPTDKALQALPLEQQNFLFHQDN--KDTLKEYLKFHVIRDARALAS
DLPRSTSWKTLQGSELSVKCGTGS-DIGELFLNGQMCRIVQRGLLFDVGVAYGIDCLLTD
PTLGGRCDTFTAFNVSGDCGSCVTTPR-CPRWSKPKGVKQKCLYSPA-PFMRSLEGCQQL
CTLVIPI-PRCCKGYFLPHCQACPGGPDTPCNNRGVCLDQYSATGQCQCNTGFNGTACEL
CWPGRFGPD-CQPCGCSEHGQCDEGITGSGQCLCEAGWTGRFCDT---------------
-----------------LTVVFPVCVPPCSVHATCMENNTCVCGLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GRHKCECKSHYVGDGLDCEPEQLPLDRCLQDNGQCHPD--ATCADLHFQDMTVGVFHLRS
PLGQYKLTFDKAKEACANEAASMATYNQLSYAQK--------------------------
------------------------------------------------------------
----------------DVLAYSNSSARGQAF-LKHLTDLSIRGTLFVP

PF02469 // ENSGT00760000119025_0_Domain_27 (2569, 2664)

QNSRLLENTTLS
GRDIEHHLTNASVSFYNDLVNGTV----LRTRLGSQLLITSSQDQLHQ-------ETRFV
DGRAILQWDIIASNGLIHVISEPLKAPPMPATPAHTGLGTGIVCAVILVTGAVALAAYSY
FRLNQR-TIGFQNFESEE-DIDVLAFGKQQPENISN-PVYESSA-SAPP----ETSGDPF
TDYEEQ---EVESS--DPLGALRS---

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-------SLPSLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

GYSIFRGYII----QYNLASVIEAADAYTVFAPNNKAIEN
YIREKKAATLEEDIVRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLGFFLRNDQVYVNDA
HINYTNAATDKGVIHGLEKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1488)

IQKNRCDNNNTTI-VQGKCGKCLQ--QPICPLGTKQLG
KE-MKKCIYTLYFMGQRSPFIGCRPVCVKTVIMRECCAGFFGPQCQP

PF00008 // ENSGT00760000119025_0_Domain_13 (1488, 1524)

CPGKAG-DVCFGN
GICLDGVNGTGMCECGEGFNGTA

ENSGT00760000119025_0_Linker_13_14 (1524, 1622)

CETCNEGRYGIHCDQ--VCPCVHGRCNQGPFGDGSCE
CDVGWRGIRCDSEITKDNCNGTCHTSANCLLNSDGTALCKCAAGFQGNGTVCT----AIN
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSANADCKRTTPGRRLCVCKVGYAGDGIM

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAVCNCLPKYTGDGKSCTLINICLTENGGCSEFAICNHTGQDERTCTCKPNYTGDGF
TCRGNIYQELPKNP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQYFFQLMEHSVRDLVGPGPFTVFAPLSAAFDKEARVAD--WDK
QGVMPQVLRYHVIACHQLLLENLKLTPNATSLQGESIAISVS-QDTVYLNNDTKVISSDI
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKNLLIAPRDASGRILQNLTTVAKNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YTKFSNLIQD--AGLL
NLITDPIHIPVTLFWPTDQALQALPTQQRDFLFNQEN--KDKLKEYLKFHVIRDSKVLAV
DLPRSAAWKTLQGSELSVKCGASS-EIGELFLNGQTCRIVQRNLLFDLGVAYGIDCLLI

ENSGT00760000119025_0_Linker_18_20 (2040, 2123)

D
PTLGGRCDTFASFNISGSCGSCVSTPA-CPRGSKSKGVKQKCLYN-L-PFKRNVEGCQQQ
CIMVVQL-PRCCKGYFGRDCQA

PF07974 // ENSGT00760000119025_0_Domain_20 (2123, 2158)

CPGGPDAPCNNRGVCLDEYWATGECQCNIGFNGTA

ENSGT00760000119025_0_Linker_20_21 (2158, 2171)

CER
CWPGRFGPD-

PF00008 // ENSGT00760000119025_0_Domain_21 (2171, 2203)

CQPCGCSDHGQCDDGILGSGQCLCETGWTGRFCDT---------------
-----------------QTVLPPECTPACSTHATCKENNTCECNLNYEGDGITCTVVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCEKVAKCSQKGTKVSCSCPKGYKGDGYSCTAIDPCADGLDGGCHEHATCKMTGP
GRRKCECKSHYVGDGLNCEPEQLPVDRCLQDNGQCHPD--ADCADLHFQDTT

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

VGVFHLRS
PLGQYKLTFDKAREACMNEAATMATYNQLSYAQKAKYHLCS-AGWLETGHVAYPTAYAAQ
SCGSGIVGIVDYGIRTNKSEMWDVFCYRMK--DVNCTCKVGYVGDGFLCSGNLLQVLMSL
PSLKNFL--------TEVLAYSNSSARGQAF-LKHLTDLSIRGTLFVPENSGLGENETLS
GRDIEHHLANVSLIFYNDLVNGTI----LRTRLGSQLLITSSQDQLY-------KETRFV
NGRAILQWDIFASNGIIHVISGPLKAPPAPETSAHTGLGTGIFFAIILVFGAIAFAAYSY
FRLSQR-TIGFQHFEQKR-IS-MLQLSARSSLRISQTPRTRIPP-QLPQ----NPPTTP-
---------------------------

--------IMLQ-Y-LVIFCLGSVVQNFCCSAETAGQ-TRRCDQKSLLTIRTECRACFLN
FEVNCPDGYTKISNGTVGVRDCR-YTFEIRTYSLLLPGCRHICRKDYLQPRCCPGHWGPD
CT-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSAVCTCVHGVCNSGLDGDGTCECYSAYTGPTCDKPIP----ECAALLCPE
NSRCSPSSEDETKLECKCLPNYQGDGKSCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNQHSCTCQE
GYHGDGQV

ENSGT00760000119025_0_Linker_2_3 (309, 362)

CLPVDPCQRNFGNCPTNSTVCKYDGPGQSHCECKEH--YHNFVPGVGCSMTN
I

PF12947 // ENSGT00760000119025_0_Domain_3 (362, 397)

CESNNLCHKNANCITVAPGQTKCTCQKGYVGDGFT

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGNIMERLRELNTELRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFISILE-KVYAWPLSNLGPFTVLLPT-DNGLKEFNANELLVDNKAAQYFVKLHIIAGQ
MSTEYMNN--TDTFYTLTGRSGEIFNGDKDNHINLKLYGGKKKVKIIQGDLIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNLEPTFESNNEQTIMTMLQT--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHTLDEEGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPYTQLEVATLISTPHVRSMANQ
LIQFNTTDNGQILANNVAMEEIEITAKNGRIYTLTGVLIPPSI--IPILPHRCDETKREM
KLGTCVSCAL-VYWSRCPPNSEPTALFTHRCVYSGRFRSL---KSGCARYCNGTVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLGGSGMCVCEEGFQGSQCQFCSDP-NKYGP
RCSKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCNKQTSACGPYI-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSETDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQPGWTGNGRDCVEIN
SCLLPSAGGCHNNATCLYVGPG---QNECECKKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGMCHPL--
------------------ANCQFTTSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGDAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSAISNLTVLVPSQQATEDMDQDEKSFWLSQSNIPSLIKYHTLQGT
YRVADLQTLSSSDTLATSLPGSFLHLEKVNGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRALMGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYIM----QYNLANAIEAASAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLHNDQIYVNEA
PINYTNVATDKGVIHGLGKVLKIQKNRCDNNDTTI-VRGKCASCSP--GLLCPLGTKPVE
NE-RKKCIYTIYFSGRRALFIGCQLICARTIITKECCAGFFGPQCQACPGNTQ-NVCSGN
GICLDGVNGTGVCECGDGFRGTACETCTEGKYGIHCDQ--ACSCVHGICNQGPLGDGSCE
CDVGWRGVHCDEVIKKDDCNGTCHTSANCIL-TDGTPSCRCAAGFRGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEIRNGGCSAKADCKKTTPGRRVCVCKADYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLGINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAACNCLPGYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLIKNGGCSKYAICNQTEQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1768)

CRGNIYQELPKNPKTSQYFFQLQEHS

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1876)

VKDLVNPGPFTVFAPSSAAFDEEARVTD--WDK
QGVMPQVLRYHVIACHQLLLENLKLISNATSLQGEPVFISVS-QGTVYLNNKAKIISSDI
ITTNGIIHIVDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLLITPRDPSGKILQNFTTLATNSG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YIKFSKLIQD--SGLL
SVITDPIHTPVTVFWPTDQALQALPAEQQDFLFNEDN--KDELKKYLKFHVIRDAKVLAV
DLPSSPGRTTLHGTDLSVKCGTGN-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PILGGHCDTFTVFDMWGDCGSCFNTPS-CPKWSKPKGVKQSCLYN-L-SFRRKLEGCQEQ
CSLAIQI-PKCCNGYFGRDCLACPGGPKTPCNNRGVCLDMYWA-GECKCNTGFNGTACET
CLPRRFGPD-CLPCRCSNHGRCDDGITGSGQCFCETGWTGPLCKT---------------
-----------------QTVLPAVCTPPCSVHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAEVAKCSQKGTKVSCSCQKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CIEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHAICKMTGP
GKHKCQCKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEKLPIDRCLQDNGQCHAD--ANCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANESATMATYSQLSYAQKARYHLCS-AGWLESGRVAYPTAFTSQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCSCKVGYVGDGFWCSGNLLQVLMSF
PSLTNFL--------TKVLTYSNSSARGHAF-LQHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

RSTLFVPQNSGLGENETLS
GRDIEHHLANISMFFYNDLVNGTT----LQTRLGSKLLITAGQDPSQQ------EEARFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTSAHTGLGAGIFFAIILVIGAVALAAYSY
FRLNRR-TIGFQHFESEE-DINVAALGKQQPESISN-PMYESTT-SAPP----EPSYDPF
TDSNEW---QLEGS--DPLGAL-----

---------MLL-P-LIPLFLGLVVQNTLSPAEATGL-AKRCDKKSFLTIRTECQACSAN
IAAKCPDGYTKITNDSFGVRDCR-YSIEIRTYSLSVPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGAESPCSGRGICDDGM-EGTGRCSCRVGFSGTACETC
AADNVFGPNCSAVCNCAHGVCNSGLSGDGTCECFSAYRGPRCDKPIP----ECAALLCPE
NSRCSPSSKDETQLTCKCLPSYEGDGRRCKPINPCLKNICHPHASCSYLGPNRHSCSCQK
GYVGDGQVCLPVDPCQTNFGNCPAKSTVCKYDGPGQSHCECKEH--YRDFVPGVGCSMTD
VCESNNPCHKNANCSTIAPGQTQCTCQKGYMGDGLTCYGSIMERLRELNTEPRGTWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISILD-RTYAWPLSNLGPFTVLLPS-DTALKGFDVKELLTDSEAARYFVKLHIIAGQ
MSTEQMND--TDIFYTLTGKSGEIFNRDEDNQLKLQLRGGK-KVKIIQGNIVASNGLIHV
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MEKTEATLESNPEQTIMKMLQS--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RHSKFRSLLE----ATNVGQALDEGGVGGPYT
IFVPSNEALDNMKTGILDYLLSPEGSRKLLELVRYHIVSFTQLEVTTLISMGRIRSMANQ
IIQF----SGQILANDVAVEETEVIAQNGRIYTLNGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-IRWSKCPADSERTALFTHTCFYRSRTQNL---KSGCAQYCNATVKIPKC
CSGFFGPDCN-PCPGGFLKPCSGNGHCIDGLGGNGTCLCEDGFQGSKCQFCSNP-NRYGP
RCNRTCLCVHGACDNRVDSDGACLPGTCREGATGRLCDRQPAACGPYV-QLCHVHATCEY
SSG---------------------------------------------------TASCVC
NEGYEGDGIL-CSKKDPCMGSTSRGGCSQNAECIQTGTGPHVCVCQQGWTGDGRDCVEIN
NCLLPGAGGCHDNATCLYVGPG---QNECECKEGFRGNGIDCEPVIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQAEKCHPL--
------------------ATCQSTASGVWSCVCQEGYE-GDGFS

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGNVLMGLSLLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

GFYQWINNASLQSMLSATSNLTVLVPSQQAIEDMDKNEKTFWLSRNNIPALIKYHTLLGT
YGVADLQILSSSAMLATSLQGSFLHLDKAAGNITIEGASIVDGDNVATNGVIHVINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLADAIEAADAYTVFAPNNEAIEN
FIREKKSTSLKEDILQYHVVLFEKLLKNDLHNGMHRETMLGFSYLLSFFLRNDQLYVNEV
PINYTNVATDKGVIHGLGKVLEIQKNRCDSNDTII-VKGSCGTCFQ--QPICPFGTKPSG
ET--RKCIYTIYFMGKRSVFIGCQPKCRRTIITRGCCAGFFGPQCQPCPGKGQ-DVCSGN
GFCLDGVNGTGVCQCGQGFNGTACETCAEGKYGVHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGVNCDSEITKDNCNGTCHTSANCLLNPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGSRVCVCKAGHTGDGII

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLPKYTGDGKT

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLIDV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFATCNHTGQGQRICTCKQSYKGDGL
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIYRELSKDPTTSKYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVQELAGPGPFTVFVPSSASFSQELALWRGLGKG
QGLMSQVLRYHMVACQELLLENLKVTTSAVTLQGEPISISVS-QDTVYINNKAKVLAGDI
ISTNGVIHIIDKWLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQHLLVTPKDASGKVLQNLTTVAMNQG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTRFSKLIQA--SGLL
SVITDPIHTPVTLFWPTDKALQAIPQEQQDFLFSEDN--KDKLKEYLKFHVIRDSKALAS
DLPRSDSWKTLQGSELSVKCGTGS-DIGELFLNGQMCRIVQRELLFDLGVAYGIDCLLMD
PTLGGRCDTFTAFNFCP--------------SPFTLGVTQSCLYNPL-PFRRSLEGCQHL
CSLVIPL-PRCCKGYFLPHCQACPGGPDTPCNNRGVCRDMYSSTGQCQCNTGFNGTACEL
CWPGRFGPD-CQPCGCSEHGQCDEGITGSGQCFCETGWTGRFCDT---------------
-----------------LTVVFPVCIPPCSVHATCTENNTCVCNLNYEGDGIKCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKTAKCSQKGTQVSCSCQRGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEVDPCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GKHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPQQLPLDRCLQDNGQCHPD--ASCMDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAASMATYKQLSYAQKASYHLCS-AGWLESGRVAYPTTYASQ
KCGSNVVGIVDYGIRPNKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSL
SSLRNFL--------TEVLAYSRSSARGRAF-LKHLTDLSIRGTLFVPQNSRLLGNKSLS
GRDIEHHLTNVSVSFYDDLVNGTI----LRTRLGSQLLITSSQDQLRQ-------ETRFV
DGRAIVQWDIIASNGLIHVIAEPLKAPPMPATPAHAGLGTGIVCAVVLVPGAIALAAYSY
FRLNRR-AAGFQRFESEE-DIDVSAFGQQQPENISN-PVYETST-SAPP----ESSCDPF
TDSEEQ---EVESS--DPLGALRA---

------------------------------------------------------------
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------------------LECPGGAGSPCSGRGRCDEGM-EGNGSCSCQEGFGGTACESC
ADDNLFGPSCSAVCSCVHGVCNSGIDGDGTCECYSAYTGTNCNKPIP----ECAALLCPE
NSRCSPSSEDETKLECKCLPNYKGDGKYCEPINP

PF00008 // ENSGT00760000119025_0_Domain_2 (275, 309)

CFQNICHPHAHCTYLGPNRHSCTCEE
GYQGDGQV

ENSGT00760000119025_0_Linker_2_3 (309, 362)

CLPADPCQVNFGNCPTKSTVCKYDGPGQSHCECKEH--YHNFVPGVGCSVTD
I

PF00008 // ENSGT00760000119025_0_Domain_3 (362, 397)

CESNNPCHKNANCTTIAPGQTKCTCQKGYVGDGST

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGNIMERLRDLNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

RL
TTFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFSVKELLMDNEAAQYFVKLHIIAGQ
MNTERLNN--TDTFYTLTGKSGEVFNRDKDNQLKLKLYGGKKKVKIIQGNMIASNGLLHI
IDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KMDPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RHSKFRSLLE----ETNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGILDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
IIQFNTTNNGQILANGVAMEEIEVAAKNGRIYTLNGVLIPPSI--IPILPHRCDETKREM
KLV---------------------------------------------------------
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-------LTMIQ-Q-LTLFFFGLVVQNACSQAE-----AKRCDKKSFLTIRTECQSCSVS
LSVKCPDGYSKVTSSPVGVRDCR-YAFEIKTYSLSLPGCRHICRRDYLQPQCCPGHWGPD
CM-----------------ECPGGAGSPCSGRGTCDEGM-EGNGSCSCQDGFGGTACETC
ADDNLFGPNCSAVCNCVHGVCNNGLGGDGTCQCHSAYTGPSCDKQCPESIPECAALLCPE
TSRCSPSNEDKTKLECKCLPNYEGNGQSCQPINPCLQN

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNQHSCTCQE
GFHGDGRTCLPIDPCQTKFGNCPPKSAVCKYDGPGQSHCECKEH--YHNFVPGVGCSMTN
ICESKNPCHKYANCTTVAPGQTKCTCQKGYVGDGLTCYGNIMQQLKELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTLLLPS-DKGLKGFDVKDLLVDNEAARYFVKLHVIAGQ
MSTEQMND--TDTFYTLTGTAGEIFNREKDNQLKLKLHGGKTKVEIIHGNIVASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMMEPTFESNPQQTIMKVLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

KYSKFRSLLE----ETNVGHALGEDGVDGPYT
IFVPTDEALGNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHVRSMANQ
VIRFNITSNGQILANDVAMEETEVPAKNGRIYTLSGVLIPPSI--VPILPHRCDETRREM
KLGTCVSCSL-VYWSRCPAGSEPTALFTHKCVYSSRIQTL---KSGCARYCNATMMIPKC
CKGFYGSDCN-PCPGGFRNPCSGNGQCADGLSGNGTCICEDGFQGSQCQFCSDP-NKYGF
RCDKTCLCAHGACDNRIDSDGACLAGSCRDDTAGRFCNKQTSACGPYM-DFCHIHATCEY
SNG---------------------------------------------------TASCIC
KEGYEGDGMM-CSEKDPCMGST-PGSCSPNAECIRTGTGTYQCLCQQGWTGNGRDCVEIN
NCLLP

PF12947 // ENSGT00760000119025_0_Domain_9 (1026, 1062)

GTGGCHDNAICLYVGPG---QNECECKKGFQGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPVIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTEKCHPL--
------------------ATCQFA-SGVWSCVCQDGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAALELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWIHNASLQPMLSTAANLTVLVPSQQAIKDMDQGEKSFWLSSKNIPALIKYHTLPGT
YGVADLQTLSSSNMLATSLQGNFLHLEKAAGNITIEGASIVDGDNAATNGVIHIISKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFQGYII----QYNLANAIEAADTYTVFAPNNNAFEN
YVREKKVTTLEEDVLRYHIVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLRDNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNETTI-VRGKCGRCPH--KATCPLGMKPLG
NE-TRKCIYTNYFMGKWSMSIGCQPKCVKTIITRACCAGFFGPQCQACPGEGQ-NVCNGN
GICLDGVNGTGVCQCGQGYSGTACETCEEGKYGIHCDQ--VCPCVHGRCNQGPSGDGSCD
CEVGWRGVNCDQVMN----------TPLCLLNPDGKASCQCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CVTSNGGCSPKADCKRTTPGRRVCTCKAGYAGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINI

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAVCNHTGREERTCTCKLNYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1770)

CRGSIYQPCL---------PSLQGHAVR

PF02469 // ENSGT00760000119025_0_Domain_17 (1770, 1876)

DLAGPGPFTVFAPTSDSFAKEPLIKD--WDQ
QGLMPQVLRYHMVACQQLLLENLKLTPNATTLQGEPIAISVS-QDTVYINNKAKILASDI
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1907)

PQDMIITPRDIYKRIKQNLTTVAINHG--YI

PF02469 // ENSGT00760000119025_0_Domain_18 (1907, 2039)

RFSKLIQD--SDLL
SVITDPIHTPVTVFWPTDQALQALPLEQQDFLFNQNN--RDKLKEYLKFHVIRDSMALAV
DLPRAASWKTLQGSELSVKCGTGS-DIGELFLNDQMCRIVQRGLLFDRGMAYGIDCLLMD
PTLGGHCDTFTTFSVSGECGSCINTPR-CPTWSKPKGVKRKCLYHLL-PYRRNLEGCQQQ
CSLVIQI-PRCCKGYFLPDCQACPGGPDTPCNNRGTCHNQYSAAGQCQCNTGFNGTACEL
CWPGRYGPD-CQPCGCSEHGQCDDGITGSGQCFCESGWTGHFCDT---------------
-----------------QTAVLPVCMPPCSVHATCMENNTCECNPNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKAATCSQKGTVVSCSCQKGYQGDGYS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CMEIDRCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GRHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGMCHPD--ANCADLHFQDNNVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANKAASMATYNQLAYAQKAKYHLCS-AGWLESGRVAYPITYASP
KCGSNFVGIVDYGPRVNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2564)

YRMK--DVNCSCKAGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSKSSSRGRAF-LKHLTDLSIHG

PF02469 // ENSGT00760000119025_0_Domain_27 (2564, 2664)

TLFVPQNGGLQGDETLS
WRDLEHHLTNVSL-FYSDLVNGTT----VQTRLGSQLLITCSQDQLQQ------NETRFV
DGRAIMQWDVIASNGIIHVISRPLKAPPP---STHTGLGTGVFCAVVLVIGAIALAAYSY
FRLKQR-TIGFQNFKSEE-DIDVANFGKQQSENISN-PMYESST-PAPP----ETACDSF
VDSEDP---QLESS--DPLGAIVRT--

MGRSQYLLSMLL-P-LIPLFLGLAVQNTCTPAEATEL-VKRCDKKSFLTIRTECQACSAN
FAVKCPVGYVKITNDSLGVRDCR-YSIEINAYSLSVPGCQHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGAESPCNGRGTCDEGM-EGTGSCSCRAGFRGTACETC
AADNMFGPNCSSVCSCVHGVCNSGLNGDGTCECFSAYRGPRCDKPIP----ECAALLCPE
NSRCSPSSQDETKLKCKCLPSYQGDGQHCKPINPCLKSVCHPHASCTYLGPNRHHCSCQK
GYRGDGQVCLPVDPCQTNFGNCSTKSTVCKYDGPGQSHCECKEH--YRDFVPGVGCSMIN
V

PF12947 // ENSGT00760000119025_0_Domain_3 (362, 397)

CESNNPCHKNANCSTVAPGQAQCTCRKGYIGDGLT

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGNIMERLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISILD-RTYAWPLSNLGPFTVLLPS-DKGLKGFNVKELLMDNEAARYFVKLHIIAGQ
MSTRQMND--TDAFYTLTGKPGEIFNRDKDNQLKLKLDGGE-KVKIIQGDIAASNGLIHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKTEPTLESNPEQTIMKILQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RFGRFSSLLE----KTNVGHTLDEGGAGDPYT
IFVPSNEALDSMKEGTMDYLLSPQGSRKLLELVRYHIVAFTQLEVATLVSTPHIRTMANQ
FVHFNITRNGRILVNDVAVEETEVAAKNGRIYTLTGVLVPPSI--VPILPHRCDETKREM
RLGTCVSCSL-IRWSKCPADSEPMVLFTRNCVYRSRTQNL---KSGCAQYCNTTIKIPKC
CSGFFGPDCN-PCPGGFLNPCSGNGQCIDGLRGNGTCICEDGFQGSRCQFCSDP-NRYGP
RCNRTCLCVHGACDNRVDSDGACLSGTCREGTSGRFCDKKPSACGPYV-QLCHIHATCKY
SNG---------------------------------------------------TASCVC
NEGYEGDGTL-CSKKDPCVGSTSRGGCSPNAECIRTGTGAHVCVCQQGWTGDGRDCVAIN
NCLLPGTGGCHDNATCLYIGPG---QNECECKKGFRGNGIDCEPVISCLEQAEKCHPL--
------------------ATCQADASGVWRCVCQEGYE-GNGLLCYGNMLMELSRLSE

PF02469 // ENSGT00760000119025_0_Domain_11 (1139, 1261)

TA
VFYQWINDASLQSMLSATPNLTVLVPSRQAIEDMDKNERTFWLSRNNIPALIKYHTVRGT
YGGADLQNLSSSDMLATSLQGSFLRLDKADGNITIEGASIVDGDNAATNGVIHVINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PPRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

NYSIFRGYII----QYNLASAIEAADAYTVFAPNNEAIES
YIREKKAMTLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLHNDQLFVNDA
PINYTNVATDKGVIHGLGKVLEIQKNRCDENDTTI-VRGICGKCSQ--ETICPLGTKPLV
STILLS-----YLKKKKTCIFFCPLPSLGLFLTKACCAGFFGPQCQACPRKDQ-NVCSGN
GFCLDGVNGIGTCRCEQGFNGTACETCVEDRYGVHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGTWCFSEN------VICPFHCSCLLDPDGQALCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEVSNGGCSAKADCKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLPKFTGDGKA

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFATCTHTGQDQRICTCKQNYTGDGF
V

ENSGT00760000119025_0_Linker_16_17 (1742, 1768)

CRSSIYGE----------------HA

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1876)

VRELAGPGPFTVFAPSSASFDQESRIKD--WDA
QGLMSQVLRYHVVACQQLLLENLKVTTSAVTLQGEPISISVS-QGAVYINNKAKVLSGDI
ISTNGVIHIIDRLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLLITPKDASGRVL-NLTTVAMNRG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2038)

YTRFSKLIQD--SGLL
SVITDPIHTPVTLFWPTDKALQALPPEQRDFLFNQDN--KDKLKEYLKFHVIRDSKALAS
DLPRSASWKTLQGSELSVTCGTGR-DVVSLFLNGQMCRITQRGLLFDLGVAYGIDCLLTN
PTLGGRCDTFTTFNVSGDCGSCVSTPR-CPPWSKPKGVKQKCFYKSL-PFGKNLEGCRQL
CTLVIRL-PRCCKGYFLPHCQACPGGPDTPCNNRGVCSHLYSTTGQCQCNTGFNGTACEL
CWPGRFGPD-CQPCGCSEHGQCDEGITGSGQCFCEAGWTGRFCDT---------------
-----------------LTAVFPVCIPPCSVHATCMENNTCVCNLNYEGDGITCTAVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKAAKCSQQGTQVSCSCKKGYQGDGYS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CMEIDPCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GRHKCECKSHYVGDGVD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHPD--ANCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAASMATYNQLSYAQKASYHLCS-AGWLESGRVAYPTTFASQ
KCGSNVVGIVDYGNRPNRSETWDVFCYRMK--DVNCTCKAGYVGDGFSCSGNMLQVLMSL
SSLTDFL--------E-VLAYSNSSARGRAF-LKHLTDLSIRGTLFVPQNSGLMGNKSLS
GRDIEHHLTNVSVSFYDDLVNGTV----LRTRLGSQLLITSRQDQLHQ-------ETRFV
DGRAILQWDIIASNGLLHVISEPLKAPPVPASPAHTGLRTGVVCAVILVTGAIALVAYSY
FRLNQR-TTGFQRFESEE-DIDVLAFGKQQPENVTN-PVYESSS-AAPP----ESSCDPF
PVSLSF---PPGKLGKGSAGVQDAGV-

------------------------------------------------------------
------------------------------------------------------------
-------------------------GTPCSGRGSCAEGM-DGNGTCACQEGFGGLACETC
THGNLFGPNCSSVCKCVHGVCNSGLQGDGTCECYSAYTGPSCDTPVP----ECAALLCPE
NSRCSPLKEDRTKLGCRCLPNYKGDGKNCEPINPCLQQPCHLHAHCAYLGPNQHSCTCRD
SYFGDGRVCLPLDPCQMDLGNCPPASTECKYDGPGQSHCECKQH--YHNFVPGVGCSMAD
LCKSKNPCHRKAYCTMIEPGQPRCTCQKGYVGDGFTCYGNIMERLQELNTAPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-RVYAWPLSTLGPFTLLLPL-E------EVTELLMDPKAARYFVKLHIIAGQ
MSTERMNN--TNTFYTLTGASGKIFNQDKDNQIKLELHKGKKKVKIIEGNIVASNGLIHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKIEPTFKSNSKETICIVLPS--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

HKKFCSLLE----VVNLIYDLEVRGVAGSYT
IFVPSNEALNNMKYRDLHYLLSPQGTWMLLELLRYHIIPFTQLEVATLVSTRQITTMANQ
IVEFNTTDSGQILVNGVPVENTEVAVKNGLIYTLAGVLMPPSFLHVPSSPSRCDDSNSEM
RPGSCVNCLV-AFESKCPADSEPTAVFTHRCV--YSSSSSKAPKSGCARYCNATVKVQSS
PW---APGSA-RL----------------G---MARWMLFSGL---PSFRTLDPALSVPL
PPSSGCRCVKGTCNNRVDSNGDCLPDTCQDGTFGHFCNFRAFPCGYLV-PVCDVRSFCQS
EIY---------------------------------------------------GESCIC
EDGYLYDGFG-CYEQDPCRDPD-RGGCSRNAECIKTGPGSHTCVCHRGWMGSGRDCKEIN
PCLLPSKGGCHGSATCLYVGPG---QNECECQKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQAVAPGAWSCVCQEGYE-GDGVL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGDVATELSFLPEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
AFNQWISKASLQPLLSSTSNLTVLVPSWRAIEDMDRDEKSFWLSWSDLPALIKFHTILGT
YGVADLQSLTSSDMLATSLPGGFLHLEKADGNVTIGGASIVDGDNVATNGMIHIIDKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLSGSLPNLLTRLNQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLASAIEAADSYTVFAPNNAAIEN
YIKEKKVATLGEDTLRYHVVLKEKLLKSDLHNGMHRESILGPSYHLGFFLRDQQLYVNEA
PINYTNVATDKGVIHGLGKVLGIQKNRCDNNETTV-VRGKCGKCLQ--RPICPPGTKPL-
---KTKCIYSLYFMGKRSVFIGCRQTCVRTVLTRECCAGFFGPECQACPGQRG-SACFGN
GVCMDGVNGTGACECGPGFHGTACETCVDAKYGVHCDQ--ACSCVHGRCSQGPSGDGSCD
CAVGWRGVRCDSAITEDSCNGTCHTSANCLVSPDGTATCRCAAGFQGNGTICK----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRNGGCSSKADCKRTTPGSRMCVCKAGHTGDGIVCLEINPCLENHGGCHQNHR----
-----------PCLGDGKVCTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLKKNGGCSPYAICNHTGTGERTCTCKQNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1769)

CRGYIYEELPKNPQTSQYFFQLQEHGV

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RELAGPGPFTVFAPLSAAFSEDPQIKD--WHS
QGLMPQVLRYHVVACHQLLLENLKLTPNVTSLQGEGIVISVS-QDAVYINNQAKIISGNI
INTNGVVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1911)

PRNLLASPRDSMGRILQNLTTVAAKHG--YGWLP-

PF02469 // ENSGT00760000119025_0_Domain_18 (1911, 2038)

ALQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPQEQRDFLFSPDN--EDKLKGYLKFHVIRDSKVLAV
DLPRSASWKTLQGSELSVKCGAGS-DIGELFLNGQMCRIVQRELFFDLGVAYGIDCLLTD
PSLGGRCDSFSTFNVPGDCGSCLNTPR-CPRWTKPKGVKQKCSYRMM-PFRSVLEGCRNE
CTLVIQL-PRCCKGYFLPDCQACPGGPDTPCSNRGICQKVYSAEGQCRCDNGFNGTACEL
CWPGRFGPD-CQPCGCSDHGQCDDGISGSGLCLCESGWTGHLCDT---------------
-----------------RTAVSPVCTPPCSAHATCMENNTCECNLNYEGDGITCTVVNF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAQCSQKGTKVSCNCPKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GRHKCECKSHYSGDGLA

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQNNGDCAPD--ADCVDLHFQDTTAG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHSRS
PLGQYKLNFDQASLACAKEAAVMATYTQLSYAQKAGYHLCS-AGWLDSGHVAYPTAYASQ
KCGGGTVGIVNYGVRSNKSEMWDVFCYRMK--DVNCTCRPGYVGNGVSCNGNLLQVLMSN
PLLKNFL--------KEVLAYSNSSARGRVF-LKHLTDLSIHSTLFVPPNNGLWENETLS
GRDIEHHLASVSAIFYDDFVNGTT----LRTRLGSQLLVTASRDQPDL------KEIWFV
DGRAILEWDIFASNGVIHIISRPLKAPPAPT-STHAGLGTGIFFAIILVTGSIALAVYSY
FRLNRR-AIGFRRFESDE-NVDVAALSKQPPENISN-PAYESWS-SAPP----PPPCEPL
SPSLSQ---ELDSS--DPLGAGTL---

------------------------------------------------------------
------------------------------------------------------------
------------GCL-IPPECPGGARSPCSNRGICDEGM-EGNGSCSCQRGFGGTACETC
ADDNVFGPSCSAVCNCVHGVCNSGLNGDGTCECHSAYKGPRCDKPVP----ECAALLCPE
NSRCSPSGEDETKLECKCLPNYEGDGPNCKPINPCLQNICHPQAHCSYLGPNRHSCTCQE
GYHGDGQVCLPLDPCQSNFGNCPTKSTVCKYDGPGQVRKEPQVI--W-------------
-----------CHAWTSSPDNLQCTCQKGYVGDGLTCYGNIMERLRELNTEHRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

EL
TPFISLLD-KAYAWPLSNLGPFTVLLPP-DKGLKGVNVKELLMDKETARYFMKLHIIAGQ
MNTEQMND--TDTFYTLTGKSGEIFNRDKDNQLKLKLYGGKKKVKIIQGNIVASNGLIHI
LDQA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLKPTLESNPQQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDEDGVGGPYT
IFVPSNEALDNMKDGTLDYLLSPEGSWKLLELVRYHIIPFTQLEVATLISTPHIRSMANQ
VIRFNITNNGQILANNAAMEEIEVAAKNGQIYTLTGVLIPPSI--VPILPHRCDETRREM
KLGTCVSCSL-VYWSKCPANAEPTALFTHKCVYSSRIRSL---KSGCARYCNATVKIPKC
CSGFYGPDCK-PCPGGFSNPCSGNGQCADGLSGNGTCICEDGFQGSQCQFCSDP-NKYGP
RCNQTCLCAHGACDNRINSDGACLVGTCREGTAGMFCNKQTSACGPYV-QF

PF12947 // ENSGT00760000119025_0_Domain_7 (892, 972)

CHIHATCEY
TNG---------------------------------------------------TASCIC
KEGYEGDGIF-

ENSGT00760000119025_0_Linker_7_8 (972, 984)

CSKKDPCMGST-

PF00008 // ENSGT00760000119025_0_Domain_8 (984, 1012)

PGGCSHNAECIQTGTGTYSCVCQQGWTGNGKDCVEIN
NCLLRGMGGCHDNATCLYIGPG---QNECECKKGFRGNGIDCDPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTEKCHPL--
------------------ATCQSA-SGIWSCVCQEGYE-GNGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGNAAMELSFLSEGA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFNQWIHNASLQPMLSTTLNLTVLVPSQQAIEDMDRDEKAFWLSSNNIPALIKYHMQLGT
YRVADLQTLSSSDMLATSLQGSFLHLDKAGENITIQGASIVDGNNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTVSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLASAIETADAYTVFAPNNDAIED
YIREKKVATLEEDLLRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDKNDTTI-LRGKCGKCPQ--QAVCPLGTKPLG
DE-MRKCIYTIYFMGRRSAFIGCQTKCVKTVITRACCAGFFGPQCQACPGTGQ-NTCSGN
GICLDGVNGTGLCECGQGFNGTACETCTEGKYGIHCDQ--VCSCVHGRCSQGPSGDGSCD
CDVGWRGVKCDSEITKDNCNGTCHTSANCLLDPDGKALCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRNAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAVCTHTGQDERTCTCKLNYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIYRELPKDPQTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFVPSSSSFNQEIRIKD--WDQ
QGLMPQVLRYHMVACQQLLLENLKLIPNVTTLQGEPLTISVS-QGTVYINNKARIIFSDV
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1912)

PQNLLITPKDASGRVLVSNLTV--------TGMTPV

PF02469 // ENSGT00760000119025_0_Domain_18 (1912, 2039)

FQD--SGLL
SVITDAIHTPVTLFWPTDQALQALPQEQQDFLFNQDN--KDKLKEYLKFHVIRDAMALAS
DLPRAASWKTLQGSELSVKCGTGS-DIGELFLNGQMCRIVQRGLLFNVGVAYGIDCLLMD
PTLGGRCDTFTAFNVLGECGNCINTPR-CPPWSKPKGMKQKCLYNLL-PYRRNLNGCQQQ
CTLVIQL-PRCCKGYFLPDCQACPGGPDTPCSNRGVCHDQYSITGQCQCNTGFNGTACEM
CWPGRFGPD-CQPCGCSEHGHCDEGITGSGQCLCETGWTGRFCNT---------------
-----------------QTVVFPVCIPPCSMHATCLENNTCACNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKDTQVSCSCPKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GRHKCKCKTHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHAD--ADCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACAKEAASMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTTYASK
KCGGSVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------SEVLAYSNSSAQGQVF-LKHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

QGTLFVPQNSGLQESESLS
GRDIEHHLTNVSMLFYNDLINGTI----LRTRLGSQLLITSSQDQLHQ-------ETRFV
DGRAILQWDVIASNGIIHVISRPLKAPLIPATVAHTGLGTGIFCAVVLVIGAVVLAVYSY
FRLNQR-TIGFQRFRSDE-DINVEAFSKQQPENISN-PMYESST-SAPP----EPSWDPF
KVRRHR---PVEKD--FPLAFQT----

RRGSMGSPSMLR-R-LVIILLGLVSPNSCSLAEATGQ-GNRCDKKSVLTFRTECQPCTLN
FRAKCPDGYTKVTNLTVGVEDCRYSPH----ENNSLRGCRHICRKNHLRPECCPGHWGPD
CM-----------------AHPGHRQGSLGSTGLPQ---SDVSPRGVLQEGFGGTACETC
AHDNLFGPSCSSVCKCVHGTCNNGLHGDGTCECYSAYTGPNCDTPVP----ECAALLCPE
HSRCSPLNEDRTKLRCRCLPNYRGDGKSCEPINPCLQQPCHPRAHCVYLGPNQHSCKCGD
GYFGDGHVCLPLDPCQTGLGNCPPTSTVCKYDGPGQSHCECKQH--FHHLVPGVGCSMTD
LCKSKNPCHRNAKCTMMAPGQLGCFCQKGYVGDGFTCYGDIMQRLQELDTAPGGKWQGRV

PF02469 // ENSGT00760000119025_0_Domain_4 (421, 545)

TSFISLLD-GAYAWQLSGLGPFTLLLP----------VTELLTDPEAARYFVKLHIIAGQ
MSTEQMNS--ANTFYTLTGASGEIFNQDEDHQIKLKLHKGKKKVKIIEQNIMASNGLIHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 581)

MDKIEPTFKSNRKESTKSMLQL--RHEEFYSFLISQ

PF02469 // ENSGT00760000119025_0_Domain_5 (581, 695)

TQVTDLMYNLEMRGAAGMYT
IFVPTNEAIGNMNYSDPFYHFSTK--VLYPEVLKYHIVPLTQLEVATLVSMQQVMTMANE
VIEFNITSNGQILVNGVAVEDTEITTKTGLIYTLTGGLVPPSFLRY------LSGNKREM
RLGSCVSCLA-MFTSKCPADSEPTALFTHKCVYRSRSNAL---KSGCARYCNATVTVPQC
CRGFYGPNCT-RCSED-LTPCSGNGQCADGIHGNGTCICKDGFYGSQCQFCSDR-NKYGF
KCEKKCLCVLGTCDNRIASSGACLPDTCQKGSSGTYCDRGRTRCNYFT-PECHVHATCQV
SGGEAT---------------------------------------------------VSC
YLGMELRWNQVPVGSEPW---L-FLLFLPQAECIKTGPGSHTCVCHQGWTGSGMDCEAIN
PCLLPGKGSCHSNATCLYMGPG---QHECECQEGFRGDGTDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQPGKCHPL--
------------------ATCQIVASGVWSCVCREGYE-GDGTL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGDVAT-VSHPSQVT

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

VSSPVIQKASLQPLLSSLSKLTILVPSREAIEDMDRDEKNFWLSRPNLPVLIKYHMVLGT
YGLADLQDLTSSDMLATSLPGGFVHLGKADRNVTVGGASIIDGDNVATNGVIHIIDKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLSGSLPNLITRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFQSYIT----HYDLASVIEDADTYTVFAPNNAAIEK
YIKEKKVATLE-DTLRYHVVLEEKLLRNDLHNGRHRASMLGPSYLLGFFLRSDQLYVNDA
PINYTNIATDKGVIHGLGKVLEIQKNRCDNNETTT-VRGKCAKCLQ--QPTCPPGAKPL-
---KNRCVYSLYFLGKRSVFIGCRPICVRTVITPACCAGFFGPECQACPGERG-SACFGN
GVCMDGVNGTGACKCDPGFHGTACETCADGKYGVHCDQ--VCSCVHGRCSQGPSGDGSCD
CAVGWRGVRCDSAITEDSCNGTCHTSANCLLDPDGTAACRCAAGFQGNGTVCK----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRNGGCSSKADCKRTTPGSKTCVCQAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRNAECTHT
GPNQAACNCLPTYSGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSPYAICNHTEMGERTCTCKQNYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIYEELPKDPQTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFVPSSAAFDEEPQIKH--WPS
QGLMPQVLRYHVVACHQLLLENLKLTPNVTSLQGEPIVISTS-QDTVYVNNRAKVISGNI
INTNGVVHVIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PRNLLFSPRDAAGRVLQNLTTVATNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2038)

-YSRFSRLLQD--SGLL
RVITNPIHTPVTLFWPTDHALEALPQEQRDFLFSPDS--EDKLKGCLKFHVIRD--VLAA
DLPRSASWKTLQGSELSVKCGAGG-DIGELFLNGQRCRIVQRELLFDVGVAYGIDCLLTD
PSLGGRCDTFTSFSVLGDCGSCLNTPR-CPRWTKPQGTKQKCSYRIL-PFRSVLEGCRNE
CTLVIQL-PRCCSGYFLPDCQAPIC-----------------------------------
----------PPACGCSEHGQCEDGISGSGHCLCESGWTGRLCLCGQLGGQGARKHDHAG
SPGLCKREGGWGCSPTQFLVVSPVCTPPCSAHATCMENNTCECDLNYEGDGLTCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVATCSQKDTQVSCNCPTGYQGDGYS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDLCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTAR
GRYKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGSCAPD--ADCVDLHFQDATAG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHIRS
PLGQYKLTFDDAVLACTNEAAAVATFTQLSYAQKAGYHLCS-AGWLDSGHVAYPTAYASQ
KCGGGTVGIVNYGVRPNKSETWDVFCYRMK--DVNCTCRPGYVGNGMSCSGNLLQVLMSN
PLLKNFL--------TEVLAYSSSSARGRAF-LKHLTDLSTHSTLFVPFNSGLGENETLS
GRDIEHHLTSVSVVFYNDFVNGTT----LWTRLGSRLLLTTSHDQTDP-------KTWFV
DGRAILLWDIFASNGVIHIISGPLKAPPE---VTHAGLGMGIFSAIILVTAAVALAAYSY
FRLNRR-AFRFRHLESEQ-DVDIASLHRQPWENVSN-PAYESTASPQPP----PPACEAL
P--------------------------

MARSKLPLSKLL-P-LILIFLGLLVQNACSPTEAPEL-TKRCDKKSTLTIKTECQSCSVN
IAVKCPDGYIKITNGTVGVRDCR-YSLKIQSYVLDIPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARAPCGGRGVCDEGM-EGTGSCSCRAGFRGTACENC
AAEDVFGPNCSAVCSCVHGVCNSGISGDGTCECLSAYRGPRCDKPIP----ECAALLCPE
NSRCSPSSKDETKLQCKCLPSYEGDGQTCKPINPCLKNVCHPHASCSYLGPNRHSCVCHK
GYQGDGQVCLPVDPCQTSYGNCPTKSTVCRYDGPGQSHCECKEH--YRNFVPGVGCSMTD
ICESKNPCHKNANCSTVSPGQTQCTCQKGYVGDGLKCYGNIMQRLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

QL
TSFISILD-RTYAWPLSNLGPFTVLLPS-DKGLKEVDVKELLMDKEAARYFVKLHIIAGQ
MSTEQMYN--LDTFYTLTGKSGEIINKDKDNQLKLKLYGSK-IVQIIQGNIVASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKIEPTLESNPQQTIMMMLQP--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

YGKFRSLLE----KTNVGQALEEGGIDEPYT
IFVPSNEALSNMTAGVLDYLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTLHIRSMANQ
IITFNISSKGQILANNVAVDETEVAAKNGRIYTLTGVLIPPSI--LPILPHRCNETKREM
KLGTCVRCFM-KNWSKCPTNSEPTAIFTNKCFYGSRAWNL---KIGCARYCDVTVEIPRC
CKGFFGPDCN-PCPGGFMNPCSGNGQCIDGLGGNGTCICEDGFQGSRCQFCSKP-NRYGP
QCNRTCLCVHGTCDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPYV-QFCHIHATCEY
SNE---------------------------------------------------TASCVC
NDGYEGDGTL-CSKKDPCLGSTSRGGCSPNAECIQASTGTYSCVCQRGWTGNGRDCVEIN
NCLLPSSGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQIEKCHPL--
------------------ATCQYTLSGVWSCVCQEGYE-GNGVL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNVLMELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSMLSATSNLTVLVPSLQAIKDMDQNEKSFWLSRNNIPALIKYHTLLGT
YRVADLQTLLSSHMLATSLQGSFLRLDKADGNITIEGASFVDGDNAATNGVVHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTGSLPSLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLASAIEAADAYTVFVPNNEAIEN
YIREKKATSLKEDILRYHVVLGEKLLRNDLHNGMHRETMLGFSYLLAFFLHNDQLYVNEA
PINYTNVATDKGVIHGLEKVLEIKKNRCDNNDTII-VRGKCGKCSQ--QTLCPLETKPLS
ET--RKCIYSVYFMGKRSVFIGCQLQCVRTIITSACCAGFFGPQCQACPGKGQ-NVCSGN
GFCLDGVNGTGTCECEQGFNGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGVKCDSEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTIPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRHAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLIDV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAFCNHTEQDQRTCTCKPDYTGDGI
V

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIHSELSKNPSTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFVPSSDSFNLESKLKV--WDE
QGLMSQILRYHVVACQQLLLENLKVITSATTLQGEPISISVS-QDTVLINKKAKVLSSDI
ISTNGVIHVIDTLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLITPRGASGRVLLNLTTVAANHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSKLIQD--SGLL
RVITDPMHTPVTLFWPTDKALQALPQEQQDFLFNEDN--KDKLKAYLKFHVIRDTMALAS
DLPRSASWKTLQGSELSVRCGTGS-DVGELFLNGQMCRIIQRRLLFDGGVAYGIDCLLMD
PMEGGRCDTFTTFNIPGECGSCFSTPR-CPLQSKPKGVKKKCIYNPL-PFRRDVEGCQNL
CTLVVHV-PRCCSGYFMPDCQACPGGPDTPCNNRGMCYDQYKPTGQCQCHTGFNGTACEL
CLPGRFGPD-CQPCGCSEHGQCDEGITGSG

PF12661 // ENSGT00760000119025_0_Domain_22 (2191, 2203)

QCLCEAGWTGRFCDA---------------
-----------------PTVVIPVCIPACSVHATCMENNTCVCNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GKRKCECKSHYVGDGRD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCH-PDA-NCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

IFHLRS
PLGQYKLTFDKAKEACAKEAASIATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTIYASK
KCA-NIVGIVDYGTRTNKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCNGNLLQVLMSF
PSLTNFL--------TEVLAFSRSSAQGRAF-LKHLTNLSISGTLFVPQNSGLPKNKSLS
GRDIEHHLTNVNVSFYDDLVNGTV----LKTRLGSQLLITSSQDQLHQ-------EARFV
DGRAILQWDIIASNGLLHIISEPLKAPPTAATAAHSGLGTGIFCAVILVTGAIALAAYSY
FRLNQR-TTGFRRFESED-DIDALAFGKQQPESIAN-PLYETST-PAVP----EPSRDPF
TDSGEQ---ELENS--DPLGALRS---

ARRSKYFLTMLQ-K-FMLFLLGLVVQNFCSPPETTEQ-AKRCDKTSLLTIRTECRSCLLN
LEIKCPDGYTKVTNGSVGVRDCR-YTFEIRKYSLSLPGCRHICRKDYVQPQCCPGHWGPD
CM-----------------ECPGGARSPCNGRGSCAEGM-EGNGSCSCQDGFGGAACETC
TDDNVFGPSCSAVCSCVHGICNGGVDGDGSCECYSGYTGPNCDKPIP----ECADLLCPE
NSRCSPSSQDETKLVCKCLPNYQGDGQYCEPINPCLKE

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHALCTYEGPNRHSCTCQE
GYHGDGRVCLPVDPCQTNYGNCSAKSTVCIYDGPGQSHCECKKH--YRDYVPGVGCSVID
VCKLNNPCHRNANCTTIAPGQTKCTCRKGYVGDGSTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLRGFSVKELLMDKESAQYFVKLHVIAGQ
MNTESMNN--TDTFYTLTGKSGEIFNDDKDNQIKLKLYGGKKKAKIIQGNIVASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKMAPTFESNAEKTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEDGAGGPYT
VFVPSNEALVNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
IIQFNTTNNGQILANGVAMEDTEVNAKNGRIYTLTGVLVPPSI--VPILPHRCDETKREM
KLLTNPQRTSKHRLSAFFPLAFFQTLFTHRCVYTGRIRSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLDGNGTCICQDGFQGSQCQFCSDP-NKYGP
RCDKKCLCIYGTCNNRIDSDGACLAGTCREGSTGTFCHKQTSTCGPYV-QSCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGSL-CSETDPCTGFT-PGGCSHNAECIKTGPGTHTCVCQQGWTGDGRDCSEIN
NCLLP

PF12947 // ENSGT00760000119025_0_Domain_9 (1026, 1062)

GTGGCHVNATCLYVGPG---QNECECKEGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEEITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQFTSSGVWSCVCQEGYD-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGN---ELSFLSAAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFNQWINNASLQAMLSATSNLTVLVPSPQAIENMDQDEKAFWLSKSNIPALIKYHVLLGT
YRVADLWALSPSDMLATSLQGNFLHLAKADGNITIEGASVIDSDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PRRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

NYSIFRGYII----QYNLASAIEAADAYTVFAPNNDAIEN
YIREKKIATLEEDVLRYHVVLEEKLLKNNLHNGMHRETMLGVSFFVGFFLRDDQLYVNEA
PINYTNAATDKGVIHGLGKVLEIQKNRCDNNDTTI-VQGKCGKCSQ--QPICPPGTKPLG
EE-TRRCIYTFYFMGKRSVFIGCQPNCMKTVITRECCAGFFGPQCQPCPGKAE-NVCFGN
GICLDGLNGTGVCECGEGFGGTACETCTEGKYGPQCDQ--ACSCVHGRCNQGPSGDGSCD
CEVGWRGVTCDSEITKDDCNGVCHTSANCLLNPDGTASCRCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSAKADCKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCHKNAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTFINT

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCNCKPNYIGDGL
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1770)

CRGTCHVAPPSFP---------QEHSVR

PF02469 // ENSGT00760000119025_0_Domain_17 (1770, 1876)

DLSGPGPFTVFAPLSAAFDEEPRIKD--WDK
QGLMPQVLRYHVIACHQLLLENLKLTPNATSLQGESIVISVS-QDTVYINNKAKIISSDL
INTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLVTPKDASGRILQNLTTVAINHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFHNLLQD--VGLL
SIITDPIHTPVTLFWPSDQALQALPPEQQDFLFNQDN--KDKLKEYLKFHVIRD--ILAV
DLPRSAAWTTLQGSELGVKCGTGR-DVGELFLNDQACRIVQRELLFDLGVAYGIDCLLID
PTLGGHCDTFAAYNFSVS--------------AKISGVKQKCRYY-L-SLRGYVEGCREQ
CVMVVRL-PRCCKGYFGRDCQACPGGADAPCNNRGVCLDQYSGLGECKCHTGFNGTACEL
CLPGRFGPD-CQPCGCSDHGQCDDGTAGSGQCLCETGWTGRFCDT---------------
-----------------QTVLPPVCTPPCSADATCKENNTCECNLSYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTRVSCSCQKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CIEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHRCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPERLPVDRCLQDNGLCHAA--ASCTDLHFQDATVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAYSSQ
NCGSGVVGIIDYGQRNNKSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------REVLAYSNSSARGRAF-LKHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

RSTLFVPQNSGLGENETLS
GRDIEHHLANVSVFFYEDLVNGTV----LQTKLGSQLLISSSQDQQQL--------TRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPLV-IHAGLGTGIFFATILIVGAAALAAYSY
FRLNRR-TIGFQHFESEE-DINVAALGKQQPENIPN-PLYESTP-SAPP----EPSCDPF
MVSLLL---YLEPD--DPLGAL-----

WRRYSGFINMPP-R-FVIIFLGLVLQKACPL-------GNRCDKKSVLTVSTACVPCSAN
SKIVCPPGYTKITNESAEGERCRY-------SLLSLPGCRYTCQRDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCGGRGSCADGI-EGNGNCSCQEGFGGTACEVC
AQDNLFGPSCSSVCTCVHGVCKNGPQGDGTCNCYSAYTGPTCDTRNC-------------
-----------------------GAALCCDPINPCLEHPCNPHAHCTYLGPNRHSCTCGQ
GYTGDGRVCIPVDPCQTNFGNCHPRTTQCKYDGPGQSHCECKEH--YHGFVPGVGCSMTD
L

PF12947 // ENSGT00760000119025_0_Domain_3 (362, 397)

CKSKNPCHSKASCTMAEPGQTQCTCQKGYVGDGFT

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGSIMERIQELNTTPRGKWLG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFILLLD-KVYAWPLSSLGPFTLLLPL-EQEPKAFSVKELLLDPTAARQFVKLHIIAGQ
MSMEQMNN--TDTFYTLTGAPGRIFNRDKDNQLRLELHAGKKKVTVIEGNIIAANGLIHI
LDTA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIKPTFEGNSEKTIMALIPP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSRFRALVE----KTNLKSTLDENGAGGPYT
VFLPSNGALNSMKNDDLHFLLSPEGSQKLLELVRHHIIPSTQLEVATLISTLQIRTMANQ
IIKFNITSNGRILANGVAVEDTEVTAKNGHIYTLASVLLPPSI--IPILPHRCDETKSEI
KMGSCLRPHFPRGWDCRPHCSCPLALFTRNCVYNTKTNTP---RAGCARYCNGTVRVPEC
CRGFYGPDCS-QCPGGFSNPCSGNGQCADGISGNGTCICKDGFYGSHCQFCSDR-NKYGP
RCEKKCLCSLGTCDNSVHSDGACLQGTCRDRSRGRFCDVRFLYCGYSA-HMCHVHAVCIY
KQN---------------------------------------------------TFSCIC
KDGYEGTGLE-CSEKDPCADST-RGDCSRNAECIKTGPGTHICVCQPGWTGSGRDCVEIN
PCLLPSRGGCHSNATCLYVGPG---QNKCECRKGFRGNGIDCEPIISCLEQPEECHPL--
------------------ATCQVAASGLWSCVCRDSYK-GDGLLCYGDVALELSFLSE

PF02469 // ENSGT00760000119025_0_Domain_11 (1139, 1261)

AA
TFYQWIRNASLQSLLSASSNITVLVPSQQAIEDMDRDEKNFWLAQSRIPVLIKYHTLLGT
FSVTDLQSLPSSDTLATSLQGSILRLQKADGNVTIGGAAIISGDNVATNGMIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PPRGLSSSLPSLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYIM----HYELESAIEAADTYTVFAPNNAAMEH
YIREKKITTLEEDTLRYHVILEQKLLKNDLHNGMHRETMLGPAYLLGFFLRGDQLYVNEA
PINYTNIATDKGVVHGLGTVLEIQKNRCDSNETTI-VRGKCDKCPY--PPICPPGTKMLV
S--RSPCIYTIYFMGRRSVFIGCRPTCVRVVITRACCAGFFGEQCQACPGQRG-DVCFGN
GICMDGMNGTGRCECGPSFSGTACETCVDGKYGVHCDQ--ACSCVHGRCSQGPSGDGSCE
CDVGWQGVKCDRAVTEDNCNGTCHTSANCLVQPDGTASCRCAAGFQGNGTVCK----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRNGGCSSKADCKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRNAECTHT
GPNQAVCNCLPTYTGDGKA

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTHINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSPNAICKHTETGERTCTCKQNYTGDGL
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1768)

CRGSIYEELPKDPRTSQYFFQLQEHK

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1876)

VRELAGPGPFTVFVPVSAAFNKEPRLKD--WDR
QGLMSQVLRYHMVACHQLLLENMKLPPNVTSLQGEPIVISAS-QDTMYINKKAKVISSNI
ICTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLVTPRDASGRILHNLTTVATNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YSRFSKLLQD--SGLL
DTITNPIHTPVTLFWPTDRALQALPQEQQDFLFSEDSTGSDKLMAQLKFHVIRD--VLAA
DLPRSASWKTMQGSKLSVKCGAGS-HIGELFLNGQVCRIVQRELLFDLGVAYGIDCLLVE
PTLGGRCDTFTVFKVWGDCGSCLSIPK-CPGWSKRKGVTEKCFYQAT-SGGPVLEGCQYN
CALVAQV-PNCCNGYFLPDCQACPGGSDTPCNNRGVCQ-SYSAREQCLCDFGFNGTACEL
CWPGRYGPD-CQPCNCSIHGQCDEGISGSGQCLCESGWTGRFCDT---------------
-----------------PKAVSPVCRPPCSAHATCVENNTCECNLGYEGDGITCTVVAF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAQCSQKGTKVSCRCPTGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CMEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEQATCTMTGP
GKRKCKCKSHFVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEKPPLDRCLQNNGYCHPE--ADCVDLHFQDATLG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHVRS
HLGQYMMTYDDAMLACSFEDAVLATYSQLSYAQKAGYHLCS-AGWLKGRRVAYPTAFASP
KCGGNAVGIVDYGIRPNVSETWDAFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2554)

YSMK--EVNCTCKMGYVGDGVMCNGNLLQILMSF
PFLEDFL--------TKVLAYSNSSARGQAF-L

PF02469 // ENSGT00760000119025_0_Domain_27 (2554, 2664)

KHLTDPATNDTFFVPHNNVLAENKTLS
GRDIEHHLVNVSKVFFRDLINGTV----LQTRLGSQLLITSGRREHQY-------DMIFV
DGRAIVLADILATNGIVHIISEPLEAPPAPETPTHTGLRTGVFCATILVIGATALAAYSY
VRLSRR-GIGFRRFKPEE-DITVAVFSKQCQDNISN-PTYESVSA-EPP----PPPGDPE
---------------------------

GGGARRFPTMLRCA--RVILLGLFLQKSCSLAAAPEQ-GNRCDKKIVLTVTTPCQPCTVR
L--PCLNGFT-----SAGVQDCRYYLS----LSVFEPGCRQVCQKNQSQPECCPGHWGPD
CM-----------------ECPGGAKSPCSGRGNCSEGI-EGNGSCSCLEGFSGTACETC
TQDNVFGPNCTSVCKCVHGLCNSGLQGDGTCECYTGYTGPNCDTPVP----ECASLLCPE
NSRCSPQSEDRTKLECRCLPGYRANGKDCDPINPCLHLPCGPHARCNYLGPNQHSCMCGE
GYLGDGLVCLPEDPCQADFGKCPPESTVCKYDGPGKSHCECQEH--FHSFLPGVGCSMTD
LCKTKNPCHGNANCTMAAPGQTQCICPQGYVSNGFTCYGNIMERLQELDTVPRGTWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TTFISLLD-KAYAWPLSSLGPFTLLLPSSEKEPKEFNVKELLRDPEAARHFAKLHIIAGQ
MSMEQMNN--SDTFYTLSGVPGRISNRDKDNQIKLELHGGKKKVKIIEGNILASNGLIHI
LDAA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNIKPTLESDSKQTIAKLIPE--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RCSRFRALLQ----ATNLASTLDKDGDNGPYT
VFVPSNEALLSMKTDDLRYLLSPEGSKKLLELVRYHIVPSTQLEVATLVSTRQIRTMANQ
IIRFNVTANGRILANDVAMEDIEVTAKNGRMYTLGGVLIPPSI--LPILPQRCDETQSET
VQGSCVSCAV-VFHSSCPVNAVPMVSR-----------GL---HSGSGGARDVSSQIPKC
CKGFCGPDCI-PCQGALLNSCPPNRQYVKDINGNGTCVCKDGFYGSQCEFCSDR-KSYGP
QCDQKCHCVLGTCDNRVDSTGACQPRSCRPGIHGKFCDTRFLFCGPFRLHILC-------
------------------------------------------------------------
-------------------------------D-----HSGHLCICQPGWTGNGRECVEIN
PCLLPSKGGCHSNATCLYVGPG---QVSCCCQKGFRGDGIDCQPI-TCLEQSGMCHPMVS
CYTHRRDAPERGQVRSLLATCQVAASGEWSCVCQEGYK-GDGFLCYGNVAVELSLLPEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
AFNQWVKNALLQPVLSASSNLTILAPSQQAVEDMNPDEKNFWLSESNIPALIKHHTLPGS
YSVEDLQSLPSPGTLATSLQGSVLPLQKVDGNVTLGGAAIINGDNMATNGVIHIISKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PERSLSGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSAFRGYIL----HYNLASVIEAADAYTVFAPNNDAIKS
YIREKKVSSLEEDTIRYHVVL-EKLLKNDLRHGLHRETLLGPSYMLGFFLRGNQLYVNEA
PINYTNAATDKGVIHGLEKVLEIQKNRCDNNETIT-IQGKCEHCQK--PPICPPGTKPLE
KR--SPCVSSFYFMGKRSVFIGCRPTCTRTVITRSCCAGFFGPQCQACPGQLG-STCFGN
GICMDGVNGTGMCACDPGFQGTACETCVDGKYGIHCDQ--ACTCVHGRCNQGPSGDGSCD
CDVGWRGVSCDSAITEDHCNGTCHTSANCLLSPDGNASCSCAAGFQGNGTVCK----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRNGGCAPEAYCKRTTPGSRVCECKADYTGDGIVCLGRGLSLTCRGGGA-WASAAGT
APHS--ARCLPG-TGAGFCSAEINP

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLENNGGCDRNAECTHTGPNQRTCTCKQNYVGNGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1769)

CRGHIYEELPKDPQTSQYFFQLQEHKI

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RDLVGEGPFTVFAPLSAAFDREPRIKD--WDR
LGLMSQVLRYHIVACQQLLLENMKLTPNVTSLQGEQIVISVS-QDAVSINNKAKVIASDI
MNRNGVVHIIDTLLSPQNLLVTPRDASGRVLVGNECARPVDGSEYPISA---------L-
--TE-------KYEWDCPLFPS-------------PS--RPLPRPFPPPPAPSP-IPLPL
PLPPPP---PPPSPSSTP-LPLPFLSQGQLFLNDQKCRIVQRELLFDLGVAYGIDCLLIE
HSLGGHCTVFSTYDVMGDCGNCLSTPK-CPAWSKPKGVTQTCTYRRI-NHARSLQGCRNE
CVMTLTL-PKCCKGYFQPDCQACPGGPDTPCNNRGTCLEMLSLDGQCLCNPGFNGTACEL
CLPRHFGPD-CQPCNCSAHGQCDDGISGSGQCLCDSGWTGSSCDT---------------
-----------------HTAVVPVCKPPCSVHAVCRENNTCECGLHYEGDGITCTAVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAQCSQKNTTVSCSCPNGYQGDGYS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CVKIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKRKCKCKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLLWVF------YCHPD---------ADYTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHVRS
PLGQYKLTFDTARATCASEAATVATYNQLSYAQKAGYHLCS-AGWLDSGHVAYPTAYSSR
KCGGGAVGIVDYGVRTNKSEVWDVFCYRMK--DVNCTCKAGYVGDGTSCSGNLLQVLMSS
STLNVFL--------TEVLAYSNSSARGRAF-LRRLTNLSVPSTLFVPLNIELGENETLT
GRDIEHHLANASAVYYEDLVNGTV----LWTPLGSPLLITTSREELSL------NETRFV
DGRAIVLWDMFAANGVIHVISRPLKAPPAPT-SAHAGMGTGIFSAIILITGAVALAAYSY
FRLNRR-AIGFQRFESEE-DINVAALGKQRPENISN-PMYEESRSSAP-------ACNPL
AVSGRWDPGELDDS--DPLGAGA----

--------MMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTMITSGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPD
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH--YQNFVPGVGCSMTD
ICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDMFYTLTGKSGEIFNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHALDEDGVGGPYT
IFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP-NKYGP
RCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTL-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEIN
NCLLPSAGGCHDNASCLYVGPG---QNECECKKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ASCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELTCPFGTKSLG
NE-KRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
YGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVISVS-QSTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDNSGRILQNLTTLATNNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGR-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLETGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASQDPLQP------TETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAYSY
FRINRR-TIGFQHFESEE-DINVAALGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSEER---QLEGN--DPLRTL-----

--------VMLQ--ILILSFLGLVVPNFCALTETPEQ-AKRCDKKAVLTIKTECQACSDN
SAVNCPEGYTKITKGSFGIQDCR-FTYGPRGYSITLPGCRHICKKDYVQPQCCPGHWGPD
CMXXXXXXXXXXXX-----------------XX-XXXXXXXXXXXXXXXDGFGGTACETC
ADDNFFGPNCSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHCECREHFHFHDYVPGLGCSMTD
L

PF00008 // ENSGT00760000119025_0_Domain_3 (362, 397)

CESQNPCHQHANCTTIAPGQTRCTCRKGYVGDGSK

ENSGT00760000119025_0_Linker_3_4 (397, 464)

CHGNILERLQELNIEPGGKWQGKL
TAFTSLLXXXXXXXXXXXXXXX--XXXXXXXXXXXXXVKELSM

PF02469 // ENSGT00760000119025_0_Domain_4 (464, 547)

DTQDAQYFVKLHIIAGQ
MSSEQMKN--TNIFYTLTGKAGDIFHDERDNLLKLKLLGGKKRVKIIQSDIIASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

NLEPSFMSNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 648)

RYSKFRSFLE----KTNMGQALEEGGAGEPYT
IFVPRNEALDAMKPDTLNYLLSPKGSRKLLELIRYHIVPFTQXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXGTCLSCSL-MNWSKCPENAEPMMVFTHNCAQRGRVRIL---RGGCARYCNATVTIPKC
CRGFYGRDCI-QCPGGFVNPCSRNGQXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X----
--------XXX--XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXX--------------X--X-XXXXXXX--------XXXXX------------XXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXADCLPTGSGTHTCVCQQGWTGDGRDCSEIN
ECLLPTKGGCHPNATCLYVGPG---QHECECK-GFQGNGIDCAPVTSC-EQAEMCHPL--
------------------ASCQRAPSGVWSCVCQEGYE-GDGLLCYGDAAEELLFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAA
QFNQWINNASLQSLLSATSNLTVLVPSQQAIKDMDQDEKDFWLSKSNIPTLIKHHMLPGM
YGVTDLMTLSSTDMVATSL-GNFLHLAKAEGNITLDGASIIDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLSDSLPNLLSRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYIV----QYNLASAIEAADTYTVFAPNNDAIEN
YIREKKIATLEEATLRYHVILEEKLLKNDLHNGMHRGTMLGFSYLLGFFLRDDQLYVNDA
PINYTNVATDKGVIHGLTKVLEIQKNRCDNNDTTI-VQGKCGNCLH--TPICPLGTKPLD
KE-KHKCFSIIYFNGKRSPVIGCRARCVKTVITKECCAGFFGPECQACPGTTG-NVCFGN
GICLDGMNGSGMCVCGDGFNGTACEMCFEGKYAVHCDQXXXXXXXXXXX--XXXXXXXXX
XXXXXXXXXXXXXITMDSCNGTCHTSANCLLKPDGTASCQCAAGFRGNGTACEXXXXXXX
XXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCHQNAECTHT
GPNQAVCNCRPKYTGDGRTCTLINSCLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQNLTTVATNYG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2008)

-YSKFSKLIQD--AGLL
GLITDPIHTPVTLLWPNDRTLDALPAEKRNFLFNPNN--KDKLKEYLKFHVIRDAKVLAA
NLPRATPWKTLQGSDLKVQCGVGGRLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXX---XXXXXXXXXXX
-XXXXXXXX--X------XXX-XXXXXXXXX---XXXXXXX--XX------XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXLPPVCTPPCSAHATCKENNTCECGLNYEGDGVTCTVVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
AQDNGGCATVAKCSQTDTQVSCSCPKGYRGDGRSCTEIDPCADGLNGGCHEHATCTMTGP
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXTTM

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2429)

GVFHLRS
PKSQYKLTFDKAREACAEEAATVATYNQLSYAQKXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXEVLAYSNSSSQGQAF-LKHLEDLSIRGTLFVPQNDGLQGDK---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGHWGPD
CI-----------------ECPGGAESPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPSCSAVCNCVHGVCNGGLDGDGTCECYSAYTGPKCDKPIP----QCAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPRAHCTYLGPNRHSCTCQE
GYRGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
ICKTNNLCHRNANCTTVGPGQTQCMCRKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DEGLKEFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKNKVKIIQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLAGNGTCICKEGFQGSQCQFCSDP-NKYGP
QCNKKCPCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SSG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QA---------------------------------
-------------------NCQSTSSGVWSCVCQEGYE-GDGFLCYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATKDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIAN
YIREKKVLSLKEDVLRYHVVLEEKLLKNDLHNGMHRKTMLGFSYFLGFFRHNNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTRPLS
NE-KRRCIYTSYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCLPCPGNAQ-NVCFGN
GICLDGVNGTGVCECEEGFSGTACETCTEGKYGTHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGMCHTSANCLPDSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYMGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNRAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGNIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLILISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQN--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGSCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYTGTGMCKCNTGFNGTACEM
CWPGRFGPN-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANETATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCSCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMSLTHTGLGAGIFFAVILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESAT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

--------TMLQ-N-FILFFFGLVVQNLCSPPETTEQ-AKRCDKKSLLTIRTECQSCSLN
FGIKCPDGYTKITSGTVGIRDCR-NTFEVRTYSLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCSGRGNCAEGM-DGNGSCSCQEGFGGTACEAC
ADDNLFGPSCSAVCTCVHGVCRS

PF04863 // ENSGT00760000119025_0_Domain_1 (204, 233)

GIDGDGTCECYSAYTGPNCDKPIP----ECATLLCPE
NSRCSPSSEDETKLECKCLPDYKSDGKYCEPINSCLQNICHPLVRCTYLGPNRHICTCQE
GYRGDGQVCLPVDPCQVNFGNCPTESTVCRYDGPGQSHCECKEH--YRNFVPGVGCSMTD
A

PF00008 // ENSGT00760000119025_0_Domain_3 (362, 397)

CESHNPCHRNADCTTIAPGQTKCTCRKGYTGDGST

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

RL
TSFISLLD-KVYAWPLSNLGMFTVLLPT-DKGLKGFNIKELLMDNEAAQYFVKLHIIAGQ
MNTEQMSN--TDTFYTLTGKAGEIFSGDKDNQLKLKLYGGKRKVKIIQGNIVASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

RVAPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 671)

RYSKFRSLLE----ETNVGHVLDEDAVGGPYT
IFVPSNEALNDMKDGTLDYLLSSEGSRKLLELVRYHIVPFTQLEVATLVSTPHIRSMANQ
IIQFNTTDNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXCADGHDGNGTCVCQEGFQGSQCQFCSDP-DKYGP
QCDKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXX---------------------------------------------------XXXCVC
KAGYEGDGIL-CSEMDPCLGLA-SGGCSRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX---XNECECKKGFHGNGIDCEPIISCLEQTGKCHPL--
------------------ATCQFTSSGVWSCVCQEGYE-RRRLLCYGNAAVXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

XXX
XXXXXXXNASLQPMLSAAPNLTVLVPSQQAIEEMDQDEKAFWLTKSNIPTLIKYHTLLGT
YGVADLQALSPLDMLATSLQGNFLHLAKSDGNITIEGASVIDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QYNLASVIEAADAYTVFAPNNDAIES
YIQEKKVATLEEDVLRYHVVLEEKLLKNDLHNGMHRDTMLGSSYPLGFFLHNDQLYVNEA
PINYTNAATDKGVIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1488)

IQKNRCDINDTTV-IRGKCGKS----SPICPFGTKPLS
EE-TRRCLYTIYFMGKRSLFIGCQPKCVKTVITRECCAGYFGPQCQP

PF00008 // ENSGT00760000119025_0_Domain_13 (1488, 1524)

CPGRAE-NVCFGN
GICLDGINGTGMCECGEGFNGTA

ENSGT00760000119025_0_Linker_13_14 (1524, 1622)

CETCAEGKYGIHCDQ--XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXITKDDCKGTCHTSAXXXXXXXXXXXXXXXX----XXXXXXXXXXXIN
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKAVCKRTTPGRRVCVCKAGYAGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CREINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCHKYAECTQT
GPNQAVCNCLLKYTGDGKVCTLIDVCLTKNGGCSEFALCNHTGQGERTCTCKPNYIGDGF
TCRGNIHQXXXXXXXXXXXXXXXXEHSV

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1842)

QDLIGPGPFTVLAPLSSAFDEEPRVKA--WDE
QGLMAQVLRYHVIACHQLLLENLKLTPNATSLQGESIAISV

ENSGT00760000119025_0_Linker_17_19 (1842, 1977)

S-QXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQNLTTVAINHG--YIKFSNLIQX--XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_19 (1977, 2040)

VLAV
DLPRSATWKTLQGSELSVKCGAGS-DIGELFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDAFTAFDVSXXXXXXXXXXX-XXXXXXXXGKKQKCLYD-L-PYRRNLEGCKQQ
CTLVIQL-PKCCKGYFWPDCQXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXX

PF07974 // ENSGT00760000119025_0_Domain_21 (2174, 2203)

CGCSDHGQCDDGITGSGQCVCESGWTGRF

ENSGT00760000119025_0_Linker_21_23 (2203, 2245)

CDK---------------
-----------------QTVLPPV

PF00008 // ENSGT00760000119025_0_Domain_23 (2245, 2274)

CTPPCSAHATCKENNTCECNLNYEGDGITCTXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX---XXXXX-XXXXX
XXXX---XXXXXXXXXX-XXXXXXXXXXXXXX---XXX--XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXETRFV
DGRAI-QWDIFASNGIIHVISR-LKAPPTPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXXX-X--XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXX
XDPEDQ---PLGSS--DPLGAL-----

WRRSEYFLTMLQ-S-VILFFLGFVVQNLCSLSETAEQ-GKRCDKKSLVTIRTECQSCLVT
FGIKCPDGYTKITNGTVGIRDCR-YTFEVRAYSLFLPGCRHICRRDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCSGRGRCAEGM-EGNGRCLCQEGFSGTACEIC
AADNVFGPSCSAVCSCVHGVCNSGIHGDGTCECYSGYTGRNCDEPIP----ECAALLCPE
NSRCSPSSKEEMKLECKCLPNYKGDGKHCEPINPCSQNICHPHARCTYLGPNQHRCTCQE
GYRGDGQVCLPADPCQANFGNCPTESTVCRYSGPGQAYCECKQH--YRNFVPGVGCSMID
LCESNNPCHTHADCITIAPGQTKCTCRKGYIGDGSTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVKEFLLDNNAAQYFVKLHIIAGQ
MSTEQMNN--TDTFYTLTGKSGEIFSEDKDNQLKLKLYEGKKKVKIIQGNILASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKVVPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALNEDGVGGPYT
VFVPSDEALNNMKGGTLDYLLSSEGSRKLLELIRYHIVPFTQLEVATLISTPHIRSMANQ
IIRFNTTNKGQILVNGMALEEMEVAAKNGRIYTLRGVLIPPSI--IPILPHRCDETKREM
RLGTCVSCSM-VYWSKCPADSEPTVSVTAS----GKHTSP---QQPHGCNMHFVFQIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLDGNGTCVCQDGFQGSRCQFCSDP-SKYGP
RCDKTCPCIFGTCDNRIDSDGACLPGTCRNGSAGRFCHKQTSVCGPYV-QFCHIHATCEY
SDG---------------------------------------------------TASCVC
KPGYEGDGSF-CVEMDPCSGST-PGGCSRYAECIRTGRGTHTCVCRQGWTGDGRDCSEIN
PCLLPSAGGCHHNATCLYVGPG---QNECECKKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTEKCHPL--
------------------ATCQLTSSGIWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGN---ELSFLSAAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

VFNQWINNASLQHLLSTTSNLTVLVPSRQAIADMDQEEKAFWLTKSNIPILIKYHTLLGT
YGVADLQALSPSDMLATSLQGSFLHLVKADGNITIGGASVIDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDEMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSSFRGYII----QYNLATAIEAADAYTVFAPNNDAIES
YIREKKVTTLEEDILRYHVVLEEKLLRNDLHHGMHRETMLGFSYLLGFFLRDGQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDINDTTI-VRGKCGKCPQ--APICPFGTKPLG
QE-TRRCLYTIYFMGRRSPVFGCQPKCVKTVITRECCAGYFGPQCQPCPGKPE-NVCFGN
GICLDGANGTGSCECGRGFSGTACETCAEGKYGVHCDQ--GCTCVHGRCSQGPLGDGACD
CDVGWRGVKCDSEITKDNCNGTCHTSANCLLNPDGTALCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKAICKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CIEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLESHGGCHRHAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSEFAVCNHTGQDERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1773)

CRGNIHQE----------------HSVRDLI

PF02469 // ENSGT00760000119025_0_Domain_17 (1773, 1876)

GPGPFTVLAPLSAAFDEESQIKD--WDK
GGLMPQILRYHVIACHQLLLENLKLTPNATSLQGESLVISVS-QDMVLINNKARIISSDI
ICTNGIIHVIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLLITPRDASGTILQNLTTVAMNHG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YGKFSNLVQD--SGLL
SVITNPIHTPVTLFWPSDQALQALPREQQDFLFNQDN--QDKLKEYLKFHVIRD--VLAV
DLPRSATWKTLQGSELSVKCGAGS-DIGDLFLNSQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDVSGSCGNCISPPS-CPKWTKPKGQKQKCLYD-L-PFKRNLEGCRQL
CTLVIQL-PKCCKGYFWPDCQACPGGPDTPCNNRGVCLDQYSPSRQCKCNSGFNGTACEL
CWPGRFGPD-CQPCGCSDHGQCDDGITGSGECLCETGWTGRFCDS---------------
-----------------QTALPPVCMPPCSAHATCKTNNTCECDLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTKVSCSCQKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTAIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGRCHEHATCKMTGP
GKHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHAN--ADCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACAQEAATMATYNQLSYAQKAKYHLCS-AGWLDSGRVAYPTSYASQ
NCGSGVVGIVDYGPRNNKSEMWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------KEVLAYSNSSARGRAF-LKHLTDLSIRSTLFVPQNSGLRENETLS
GRDIEHHLSNISIFFYNDLVNGTI----LHTRLGSQLLITSSQDQRQL--------TRFV
DGRAILQWDIFASNGIIHVISKPLKAPS--GTSGHTGLGTGVFFAIILVIGAIALAAYSY
FRLNRR-TIGFQHFESEE-DIDVAALGKQQPENISN-PMYESTT-SATP----EPSYDPF
TDPGDQ---QLDSS--DPLGAL-----

--QTKVKLSL--CFPIILFFLSSLIANTFSSMEMAEQGKNRCDEETLVTTKTKCRSCSLN
YEIQCPEGYTKITNS-SGVNDCR-YHLEIRDFTLTLPGCRHICVRELLQPQCCRGYWGPD
CL-----------------ECPGGAVSPCNNKGRCFYGV-FGNGTCTCQKGFAGTACEKC
AEDNHFGPDCISVCNCVHGICNSGITGDGKCSCFSGYKGSRCDQATP----ECQELQCPE
NSQCSIFSGNRSQLECRCVPNYDWNGRQCQPINPCSKPVCDPHADCFYLGPNSHKCICQY
GYKGDGQVCMPIDPCQTNFGNCPTESTVCKYNGPGKSHCECKEH--FGKFSPGLGCSMMD
ICATNNPCHKSAECTMAAPGQTLCTCQKGYVGDGFICYGNIMDQIRDVDAKPGGQWQGKL
ISAIELFE-NAYEWPLTS

PF02469 // ENSGT00760000119025_0_Domain_4 (439, 545)

LGPFTVLVPT-NKGFEGINVKDLLSNKERAQYFLKLHIFAGQ
LELNSLNN--ASMVYTLTGKPADILNNEKDNVLRIRIHGGKEKGKILQGDIVASNGIIHI
IDKA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

LDNVEPTITSDKGRSIMTVLQDTP

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSRFRSILE----NSLVGPMLDI--YPGPNT
IFIPTNDALENLRDKALDYLLSSKGSRKLRELVQYHIVSHTQLEVASLISIRRIETMAQQ
FIYYNITDSGQILVNGVPIEETDITAKNGKIYTLSGVLIPPSI--IPILPQRCDEEKTKI
EMGTCVKCQL-SHKNSCPKDSKPVASTGNRCIYLDQTHL----QYGCTKYCNITKKEPNC
CKGFFGPDCN-QCPGGFSNPCSGNGQCMDKLKGNGTCICNAGFEGSHCQFCSDP-NKYGP
RCDQICKCVYGKCDNQIESDGICQAGSCQSGYAGKFCDTQTFPCGNYL-QFCHAHADCMF
SNG---------------------------------------------------AMSCVC
KLGYEGDGII-CSEVDPCANVI-PHGCSDNAECIKTGPGTHECVCQPGWTGNGRDCSEIN
NCLLPNFGECHSNATCLYIGPG---QNDCECKAGFRGNGYECESVNSCLEQSEKCHPL--
------------------AVCQLTSSGIWECVCSEGYK-GDGSICYGNAVEELSSLSEAA
G

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNEWIDTAAMKTLLTDATNLTILVPSRQAIQNMDQEEKDFWMTKDNILTLTRHHILEGA
YTVDDLQHLSSLKRTAKSLHGNFLSLSKRSGDVSVGGANILAGDIAATNGIIHVVDKVLT

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PPSGVSATLPKLVPRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLASEIEAASTYTIFAPSNDAIED
YLKTKRSVSLDENQIRYHVILKEKLLKNDMHNGMFRETMLGLSFKVGFFIHDAQLYINEA
PISYPNVATDKGIIHGVGKVMEIQKNRCDFNGTEI-VTGKCKSCSTY-THGCPPGTTPVP
GK-KEFCIYLHYY--RMSFLSGCQRKCAKTIITRECCAGFFGSQCEPCPGLSG-NTCLGN
GICLDGINGTGSCECEAGFEGVACEQCIKGKYGIGCDQ--ECVCAHGRCNSGIKGDGTCE
CDVGWRGVTCETEIKDDECNSTCHTSANCFLNPGGKAYCQCAAGFKGNGTYCT----AIN
ACETSNGGCSAKAICKRTTPGNRVCVCKAGYTGDGIVCFEINPCLVNNGGCDTNAECTHT
GPDQAACNCLKGYSGDGKTCTYISPCLFNNGGCGKNAYCNDTGEAERTCTCKPNYIGDGF
TCRGSIAMELSMNYNITR

PF02469 // ENSGT00760000119025_0_Domain_17 (1759, 1876)

FNGYLMDAGVKDLSGIGPFTVFAPSKEAFITELKVND--WIS
KGAMPQILRNHVVSCAGLLYNDLTSDKTVTTLQGDQLKITFS-QDSVFLNSKAKILTSDL
ICTNGVIHLIDKILI

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQRIQDFPRGQPKPVKENLKIVAAKNG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YSLFYNILES--SGLM
SLINDPLHQPITLFWPTDKVIRALPKDQQDLLFKMSD--KEKLLQYLKFHIIGSAKIFAH
ALPNADSLKTFQGSELSVKCGDDDTNTGELFLNG-RCKIVQRQLEFDDGIAYGIDCMLVD
PVLGGRCDTFLTSQLPGDCISCFRTFQ-CPSGSKVVGEVQGCSYTI---GHRILPGCQKT
CSMVIRV-PQCCKGYFGNECQACPGGPEGPCNNRGSCNEGYAGTGECSCNSGFNGISCEL
CLSGRYGLD-CKSCECTLHGQCDEGISGSGQCFCETGWTGRLCET---------------
-----------------KLASSPVCSPNCSINAVCKEHNTCQCKPYYSGDGITCTAENLC
KKANGGCHKNAKCAQTDVKVNCTCQKGYTGDGYSCTAINPCADGLNGGCDEHATCTMTGP
DKRKCECKDNYVGDGLSCEVEKSPVDRCLQNNGQCHAN--ATCADLHFQDATV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHVRS
RKGQYKLTFSQANKTCADEGATIATYAQLVYAQKANYHMCA-AGWLADGRAAYPIAYPSP
KCGGGVIGIIDYGPRINKSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2553)

YRVK--DVSCTCKTGYVGDGFTCSGNLLQVLLSF
PTLTNFV--------SKVLTYFNSSKNGQEF-

PF02469 // ENSGT00760000119025_0_Domain_27 (2553, 2664)

LKYLENLSINATLFVPNNDGLKTNETLS
GRDIEYHLSNTGTLYYEDLTNGTT----LQTRIGKMLLITHGEDQAYRISA-AQKETKYV
DGKTILEWDIIASNGVIHVIATPLKAPAIPA-ALHAGVGTGIFFVILLIIGIVALVGYSY
FRFKQG-TIRFQHFEEKD-DIDVTTLDKAQSPSISN-PNYEYST-ASPP----DSSCNPF
SVSDEQ---QLVNS--SPLEEL-----

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITSGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPD
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH--YQNFVPGVGCSMTD
ICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKKKVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHALDEDGVGGPYT
IFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCK-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP-NKYGP
RCNKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ASCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHDGMHRETMLGFSYFLSFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELTCPFGTKSLG
NE-KMRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
YGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVISVS-QSTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATNNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGR-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGIMGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLETGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASQDPLQP------TETRFV
DGRAIVQWDIFASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAYSY
FRINRR-TIGFQHFESEE-DINVAALGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSEER---QLEGN--DPLGTL-----

--------IMLQ-H-LVIFCLGFVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITSGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPQCCPGHWGPD
CI----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------CVCQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNTEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP-NKYGP
RCNKKCLCVHGTCNNRIDSDGACLPGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPITSCLEQTGKCHPL--
------------------ANCQSTTSGIWSCVCQEGYE-GDGFLCYGNAAVELSFLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

VFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLGFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTKSLG
NE-KRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--VCSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENATTEDNCNGTCHTSANCLPNSDGKASCKCAAGFQGNGTICT----AIN
ACEISNGGCSAKADCKRTTPGSRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQGERTCTCKPNYIGDGF
TCRGSIYQELPKNPKTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1909)

PKNLLITPKDTSGRILQNLTTLATNNG--YIKF

PF02469 // ENSGT00760000119025_0_Domain_18 (1909, 2039)

SNLIQ-------
--ITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDASGECGSCVNTPG-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCMPPCSAHATCKENNTCECNLDYEGDGITCTVVDFC
KQDNGGCAKVARCSQKDTKVFCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGP
GKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKARDACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIRGTLFVPQNSGLGENETLS
GQDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASQDPLQP------T--EFV
DGRAILQWDIFASNVKKRVISRPLKAPPAFRTLTHTGLGAGIFFAIILVIGAAALAAYSY
FRINRR-TIGFQHFESEE-DINVAALGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSEE----------------------

--------TMPQ---DVIPLLGLFLQSAFSQHGLMKQ-TNRCDQKSLLTMRTECKSCPLN
FDIECPNGFTKVTNGSRGVRDCR-YTYELRRYSLSLPGCRHICRKVYLQHQCCPGHWGPD
CM-----------------ECPGGAENPCSGRGRCAEGL-EGDGSCTCQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXIPECAALLCPK
NARCSTSTEDETKLECKCLPNYRGDGKYCEPINP

PF00008 // ENSGT00760000119025_0_Domain_2 (275, 309)

CLQPVCHPHAHCTYLGPNQHSCVCQE
GYHGDGQVCLPVDPCQVNLGGCPAQSTVCKYDGPGQSHCDCKDH--YHSFVPGVGCHMTD
ICQSHNPCHRNANCTTIAPGQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXVKE

PF02469 // ENSGT00760000119025_0_Domain_4 (461, 547)

LLADTQAAQYFVKFHIIAGQ
MSTELMNT--TDTFYTLTGRSGEIFSGDKDNQLKLKLCGGKKKVKILQGDMVASNGLLHI
LDRALD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KMEPMFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 639)

RYSKFRSLLE----ETSVAHALEEEGKGEAYT
IFVPSNEALSNMHDGTLDYLLSPEGSRKLLELIRYHIVPFTKXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXALFTHKCVYISKTRSL---KIGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX
XXXXXCLCIHGTCDNSVTSDGACLDGSCRGGSAGRFCHKQTVACGPYV-QFCHIHATCKY
SNG---------------------------------------------------TASCVC
KAGYEGDGGL-CTQTDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CVALA-PGGCGPNAQCLQTGAGTHSCVCQQGWTGDGRD

ENSGT00760000119025_0_Linker_8_9 (1016, 1022)

CSAIN
N

PF00008 // ENSGT00760000119025_0_Domain_9 (1022, 1062)

CLLPGAGGCHDNATCLYVGPG---QNECECKKGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPITT

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQFT-SGIWSCVCEEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAAVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

KAA
IFNHWINKASLQAMLAATSNLTVLVPSRQAVENMDQDEKDFWLSTSNIAALIKHHMLQSM
YRVSDLQALTPADMLATSLQGNFLHLEKAGENVTIDGASIIDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGALPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYVI----QYNLASTIEAADAYTVFAPSNKAIEN
YIQDKKLASLQEDVLRYHVIMEEKLLRNDLHNGMHRETMLGFSFQLGFFLHHDQLYVNEA
PINYTNVATDKGVIHGLGQVLEIQKNRCDNNDTTI-IRGKCETCHQ--QPVCPYGNETLS
RE-MKKCIYTIYFHGRRTPFFGCQAKCVKTVIXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCSCVHGRCNQGPSGDGSCE
CDVGWRGVNCDVAITSDSCNGTCHTSANCLINQDGTASCRCAAGFQGNGTVCTXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXATCNCLPKYTGDGKVCMLINI

PF00008 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAVCKHTGLDERTCTCKLGYVGDGI
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1743)

C

PF02469 // ENSGT00760000119025_0_Domain_17 (1743, 1876)

RGSIFQELPKNPRTSQYFFQLVXXXXXXXXXXXXXXXXXXXXXXXXXXXXVHD--WDK
KGIMPQILRYHVIACHQLLLENLKVTPNVTTLQGESLNISVS-QDTVTLNSKAQIISSDI
INSNGIIHIIDKLLAPQNLLITPKDANGRILXXXXXXXXXXXXXXXXXXXXXXX--XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXGDLFLNDQACRIVQRELLFDLGVAYGIDCLLTD
PTLGGRCDSFDTLEVSGVCGSCINTPS-CPSWSKAKGTKQKCLYNL--SFRKSLEGCRQL
CALVVSI-PKCCKGYFGRDCQACPGGPEAPCNNQGVCLDHYSSTGQCRCNVGFNGTACEL
CLPGRFGPN-CQXXXXXXXXXXXXXXXXXXXXX---------------------------
-----XXXXXXXXXXXXXXXLPLVCTPPCSAHATCKENNTCECNLNYEGDGIACTVVDFC
KQDNGGCARVAKCSQKNTTVSCSCPKGYTGDGYSCTEIDR

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGFNGGCHEHATCKMTGP
GKIKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2393)

CEPEQLPVDRCLQDNGQCHAD--ADCADLHFQDTT

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

VGVFHLRS
PLGQYKLTFNKAQEACAKEAAAMATYNQLAYAQKAKYHLCS-AGWLATGRVAYPTAYSSK
SCGSGVVGIIDYGPRNNRSELWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLTAS
PSLTHFVTXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXX------XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASVHTGMGTGIFFAVFLVIGSLASAVYTY
FRLKRRTTIGFQHFE---------------------------------------------
---------------------------

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LRVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGHWGPD
CI-----------------ECPGGAESPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNVFGPSCSAACNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKHCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPRAHCTYLGPNRHSCTCQE
GYHGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
TCKTNNLCHRNANCTTVAPGHTQCICWKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DEGLKEFNVNELLVDNKAAQYFVKLHIIAGE
MNIEYMNN--IDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKNKVKIIQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDEDGVSGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMKEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLAGNGTCICKEGFQGSQCQFCSDP-NKYGP
QCNKKCPCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYM-QFCHIHATCEY
SSG---------------------------------------------------TVSCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGMGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRKTMLGFSYFLGFFRHNHQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTKPLS
RE-KRRCIYTSYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCLPCPGNAQ-NVCFGN
GICLDGVNGTGVCECEEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVRCENVTTEDNCNGMCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGNIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLILISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGSCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSGTGMCKCNTGFNGTACEM
CWPGRFGPN-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANETATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFCYRMK--DVNCSCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIRGTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISGPLKAPPAPMSLTPTGLGAGIFFAVILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTR-----

---------MLQ-H-LVIFCLGLVIQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCTLN
LGVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKEYLQPRCCPGHWGPD
CI-----------------ECPGGAESPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPSCSAACNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPRAHCTYLGPNRHSCTCQE
GYRGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
TCKTNNLCHRNANCTTVAPGQTQCICRKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DEGLKEFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--IDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKNKVKIMQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--IPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLAGNGTCICKEGFQGSQCQFCSDP-NKYGP
QCNKKCPCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SSG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGIWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PRRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANAIEAADAYTVFAPNNDAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRKTMLGFSYFLGFFRHNNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTKPLS
NE-KRRCIYTSYFMGRRTLFIGCQLKCVRTVIMRECCAGFFGPQCLPCPGNAQ-NVCFGN
GICLDGVNGTGVCECEEGFSGTACEICTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGMCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGNIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVSPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQILRYHVVACHQLLLENLILISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGSCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSGTGMCKCNTGFNGTACEM
CWPGRFGPN-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPACSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANETATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCSCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMSLTHTGLGAGIFFAVILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

---------------SXXXXXXXDVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITSGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPD
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNQHSCTCQE
GYHGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH--YQNFVPGVGCSMTD
ICKSNNLCHRNANCTTIAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFDINELLVDNKAAQYFVKLHIIAGQ
MNTEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNSEQTIVTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLGGSGTCICEEGFQGSQCQFCSDP-NKYGP
RCNKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGMGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ANCQSTSSGVWSCVCQVGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINDASLQLILSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLANVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRHLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLGFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQRNRCDNNDTTI-IRGKCRTCFS--EPICPFGTKSLG
NE-KRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENATTEDNCNGTCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTAPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHLVKDLVGPGPFTVFAPLSAAFDEEARVRD--WDK
QGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATNNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSSLIQD--SGLL
SVITDPIHTPVTLFWPTDQALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PKCCKGYFGRECQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSAHATCKENNTCECKLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCDCKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAATVATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLVNVSMFFYNDLVNGTT----LQTRLGSKLLITASQDLLQP------TETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPMTLTHTGLGAGIFFAIILVIGAVALAAYSY
FRINRR-TIGFQHFESEE-DINAAALGKQPPENISN-PLYESTT-SAPP----EPSYDPF
TDSEER---QLEGN--DPLGTL-----

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LRVKCPDGYTKITNGSVGVRDCR-YTFEVGTYSLSLPGCRHICRKDYLQPRCCPGHWGPG
CIGKCLSASLQNACLFDSLECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYHGDGQVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKEH--YHNFVPGMGCSMTN
LCKTNNLCHRNANCTTVAPGRTRCICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEHMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYG--------EGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELIRYHIVPFTQLEVATLVSTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCLGNGQCADSLAGNGTCICEEGFQGSQCQFCSDP-NKYGP
QCNKKCLCVHGTCDNRIDSDGACLTGTCRGGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPGLIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLGFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-LRGKCRTCSS--ELICPFGTKPLG
NE-KRRCIYTTYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCQPCPRNAQ-NVCFGN
GICLDGVNGPGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGTCHTSANCLPNSNGTASCKCAAGFQGNGTTCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKANCKRTTPGRRVCMCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINI

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPMVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLIN
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGRKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMTLTHTGLGAGIFFAIILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

--------VMLQ-H-LIIFILGLVVQNVCSPAETTGR-AKRCDKNSFLTIRTDCRSCSLN
FGIKCPNGYTKITNGSVGVRDCR-YTFEVRTHSLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGAVSPCSGRGSCAEGM-EGNGNCNCQKGFGGTACETC
ADDNLFGPSCSGVCNCVHGVCNSGTDGNGTCECYSAYTGPNCDKPLP----ECASLLCPE
NSRCSPSKKDETKLECKCLPNFKGDGKYCEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSHCECNKH--YHSFVPGVGCSVTD
ICESN-NCHRNANCTTIA-GQTECTCQKGYVGDGSVCYGNIMERLRELNIEPGGKWQGRL
TSFISLLX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXVKGLLMDDEAALYFVKLHIIAGQ
MNTEHLNN--TDIFYTLTGRSGEIFSGDKDNQLKLKLNGGKKKVKIIQEDLVAY-NLLHI
IDRAMDKMAPTFESNTEKTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALEEDGVG----
-------------------------SRKLLELVRYHIVPFTQLEVATLISNPHIRSMANQ
MIRFNTTKNGQILANDAAMEEIEVVAKNGRIYTLAGVLVPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSTCPANSEPTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
--XXXXXXXX-------XXX-X-XXXXXXXXXXX------XXXXXXX----XXX-XXXXX
-------XXXXX-XXXXXXXXX-XXXX-XXXXXXXXXXXXXXX--XXX-XX-XXXXXXXX
XXX-------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCVC
KAGYEGDGIL-CSEMDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CTGLS-PGGCSPNAECIKTGTGTHRCVCQQGWTGNGRD

ENSGT00760000119025_0_Linker_8_9 (1016, 1022)

CSEIN
N

PF00008 // ENSGT00760000119025_0_Domain_9 (1022, 1062)

CLLPGAGGCHGNATCLYVGPG---QNECECKKGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPITS

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQLTSSGIWSCVCREGYQ-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAVVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAA
IFNQWINDASLQPMLSAASNLTILVPTQQAIKDMDQDEKTFWLSKGNIPALIXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNITIEGASIIDGDNAATNGLIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1354)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNEAIEN
YIREKKVTSLEESVLRYHVILEEK-LKNDLHNGMXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXGKCGKCPP--QPTCPPGTKPLX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XCSCVHGRCSQGPMGDGSCE
CDVGWRGVKCDSEITEDNCKGICHTSANCLLDPSGTASCKCAAGFQGNGTLCT----AIN
PCETSNGGCSAKAACKRTTPGSRVCVCNAGYTGDGIVCLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLPTYTGNGKS

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF00008 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSLFAICSHTGE-ERTCTCKPGYLGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1743)

C

PF02469 // ENSGT00760000119025_0_Domain_17 (1743, 1876)

RGSIFQELPKDPKTSQYF----EHSVRDLTGPGPFTVFAPLSSAFDKEAQVEE--WDK
QGVMSQILRYHVVACHQLLLENLKLIPNVTSLQGESIVISVS-QDKVYLNNEAEIISSDI
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLITPTDVSGKIVQNLTTVALEHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YIRFSKLMQD--SGLL
SVITDPIHTPVTLFWPTDQALQALPSEQQDFLLNPDN--KDKLKQYLKFHVIRDAKVLAV
DLPRSAPWKTLQGSQLNIRCGADG-DIGELFLNNQRCRIVQRQLLFDLGVAYGIDCLLI

ENSGT00760000119025_0_Linker_18_20 (2040, 2123)

D
PGLGGRCDTFTTFDVLGDCGSCVNTPS-CPSWSKPKDVKQKCLYNL--PFMKIVEGCQQQ
CAMVMQL-PKCCKGYFGIDCQA

PF07974 // ENSGT00760000119025_0_Domain_20 (2123, 2158)

CPGGPDNPCNNRGICLDDYFATGECKCNTGFNGTACEL
CWPGRFGPD-CQXXXXXXXXXXXXXXXXXXXX----------------------------
----XXXXXXXXXXXXXXXXLPPVCTPPCSTDAVCRENNTCECNLNYEGDGITCTXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
GKQKCACKSHYVGDGLDCEPEQLPLDRCLQDNGKCHAD--ANCADLHFQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00193 // ENSGT00760000119025_0_Domain_26 (2430, 2487)

XXXXXAKYHFCFGPGWLEGREVASPTASPSQ
NCGGGLVGIVNYGLR-NKSEKWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMST
PSLTNFLTXXXXXXXXXX--------X-XXXXXXXXXXXXXXXTLFVPQNSGLGENETLS
GRDIEHHFANVSILFYDDLINGTV----LQTRLGSQLLITSSRDQLHP------KETRFV
SGRAILQWDIFASNGIIHVISGPLKAPPAPV-----------------------------
----RR-TIGFQHFESEE-DINVEALGKQQPENISN-PMYESTT-SVPP----EPSCDPF
ADSNEP---QSDSN--DPLGVL-----

RRRSRQLLDMLQ-Y-LQLFLLGWLVQVSSSQTESPGQ-AKRCDKESVLTIRTQCKSCWLN
LGIKCPDGYTKITNNSVGVRDCR-YNYDVKSYFWPLPGCRHICRKNYLQPQCCPGHWGPD
CQ-----------------ECPGGAGSPCSGRGSCDEGM-EGSGSCSCQEGFGGTACEMC
ADDNLFGPNCSSVCSCVHGVCSNGPGGDGTCACYSAYTGPRSKSPQPQ---VCGTLLCPQ
LAFFPAPPTAQWT-QGRGLLSMTGSQSQ--------------------SQPN--------
-----------GEHCQIAF-------QVGKY--FCQSHCECKEH--YHNFVPGVGCSMIN
ICESKNPCHRNANCTTIIPGQTKCTCREGYVGDGLLCYGNIMERLRELNTEPRGKCQGRL

PF02469 // ENSGT00760000119025_0_Domain_4 (421, 545)

TSVISLLD-EVYAWPLSSLGPFTVLLPS-DSAFKASDVRALLMDKEAAKYFVKLHIIAGQ
MSTEQMNR--TDTFYTLTGKSGEIFSADRDGQLRLKLYGGKKKVQIVQGNIVAANGLIHI
LDQA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDSIQPTFVSNTKQTIMMMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 641)

KYSKFVSLLE----EANMGHSLDED---GPYT
VFVPSNEALESMKDGTLDYLLSPQGSRKLLELVRYHIIPFTQFLVLNFNI----------
---LMSEKLGQILANEVAMDETEITAKNGRIYTLTGVLIPPSI--IPILPHLCNETRRET
KLGTCVNCYL-IHRSKCPADSQISRFYIHKCVYRSTLGGL---KSGCALRCSAIVQATK-
--GWAAPG---PHPWPFPRGLSLLSQCADGLQGNGTCICKDGFQGSQCQFCSDP-NKYGP
QCNQTCPCVHGVCDNRIDSNGTCLPGTCREGTAGTFCDRQTSTCGPYV-QLCHIHATCIY
SNG---------------------------------------------------TASCVC
KEGYEGDGAF-CSFSDPCKGPT-

PF00008 // ENSGT00760000119025_0_Domain_8 (984, 1012)

RGGCSHNAECIKTKAGTHTCVCQQGWTGNGRDCVEIN
NCLLPGAGGCHANATCLHVGPG---QNECECKKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTEKCHPL--
------------------ATCRFVSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGNAAMELSFLSDAV

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFNQWINNASFQSMLSTTLNLTILVPSKQAIEDMDPKEKTFWLSKNNIEALIKHHMLVGT
YRVADLQTLSPSDTVATSLQGSFLRLDQADGNITIGGASILDGDNVATNGVIHVINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PLRGLSGYLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYMI----QYNLVNQVEAADAYTVFAPNNNAIER
YVKEKKVSTLEEDIIRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLHDDQLYVNEA
PINYTNVATNKGVIHGLGKVLEIQKNRCDINDTTI-VRGKCGVCLQHQPPICPLGSKPLV
VS-I----LSTWWQGV--------PSFVFLFQTRACCAGFFGPQCQACPGKGQ-NVCFGN
GICLDGVNGTGKCECGPGFSGTACETCAQGKYGIHCDQ--VCPCVHGRCNQGPSGDGSCD
CDIGWRGVACDRG------------KSHCLLNLDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSAQALCKRTMPGSRECVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CIEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAVCNCLPKYTGDGKI

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTHINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLFNNGGCSPFAVCNHTGGDERTCTCKMNYTGDGI
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIYKELPKDWKTSQYFFQLQV

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFAPSSYSFSEEPRLAD--WNQ
QGVIPQILRYHMVACQQLLLENLKSISHVTSLQGELLSISVS-QDTVYINNKAKVIASNI
ISNNGVIHVIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLVITPRDTSGRILQNLTTTAINHG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YHRFAKLIQD--SGLL
STITEPIHIPVTLFWPTDQALQALPAKQQEFLFNPLN--KDKLEEYLKFHVIRDAKALAI
DLLRSDSWKTLQGSELRVTCGTGN-DTGELFLNDQMCRIVQRGLQFDVGVAYGIDCLLLD
PTLGGRCDTLAAFDVLGECGSCSNTPR-CPTWSKSKGKKQKCLYHLLQPYRRNLEGCQNL
CALVVQI-PTCCKGYYLPDCQACPGGPDLPCNNQGVCINLLSASRQCQCNEGFNGTACNL
CLPGRFGPH-CQACGCSAHGQCDEGILGSGACFCETGWTGHFCDV---------------
-----------------PIVSAPVCTPPCSAQATCMENNTCECNLNYEGDGLTCTAVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKNTTVSCSCPTGFRGDGYT

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CLEIDSCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHAICTMIGR
GRHKCRCKDHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHAD--AHCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAAALATYAQLSYAQKASYHLCS-AGWLDGGWVAYPTAYASM
KCGSGFVGIVDYGPRVNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKEGYVGDGFSCSGNLLQVLMTF
PSLTNFL--------TKVLAYSNSSAKGQAF-LKHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

HGTLFVPQNSGLQENETLS
GRDIEHHLANVNITFYNDLVNGTI----LQTRLGSQLLITTSQDQLQQ-------ETRFV
DGRTILQWDIFASNGIIHVISKPLKAPPAPA--THSGLGTGISFTIILVIAAIALAAYSY
FRLNWR-TIGFQHFESEE-DIDVAAFGRQQSENISN-PTYESAT-SEPS----EPSYDPF
MDADEQ---QVESS--DPLGAL-----

TAEAQGLLNMLR-R-SMMILLGLVLQSSCSL-------GNRCDKKSALIIRTKCQSCLLN
LRAKCPDGYRKISNYTMGVRDCR-------TDSQSFPGCRHICRKEYLQPECCPGHWGPD
CM-----------------ECPGGAGTPCSGRGSCAEGM-DGNGTCACQEGFGGLACETC
THGNLFGPNCSSVCKCVHGVCNSGLQGDGTCECYSAYTGPSCDTPVP----ECAALLCPE
NSRCSPLKEDRTKLGCRCLPNYKGDGKNCEPINPCLQQPCHLHAHCAYLGPNQHSCTCRD
SYFGDGRVCLPLDPCQMDLGNCPPASTECKYDGPGQSHCECKQH--YHNFVPGVGCSMAD
LCKSKNPCHRKAYCTMIEPGQPRCTCQKGYVGDGFTCYGNIMERLQELNTAPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-RVYAWPLSTLGPFTLLLPL-E------EVTELLMDPKAARYFVKLHIIAGQ
MSTERMNN--TNTFYTLTGASGKIFNQDKDNQIKLELHKGKKKVKIIEGNIVASNGLIHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKIEPTFKSNSKETICIVLPS--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

HKKFCSLLE----VVNLIYDLEVRGVAGSYT
IFVPSNEALNNMKYRDLHYLLSPQGTWMLLELLRYHIIPFTQLEVATLVSTRQITTMANQ
IVEFNTTDSGQILVNGVPVENTEVAVKNGLIYTLAGVLMPPSFLHVPSSPSRCDDSNSEM
RPGSCVNCLV-AFESKCPADSEPTVSV---------TNSSKAPKSGCARYCNATVKIPQC
CRGFYGPDCT-ECPGGVLNTCSGNGQCVDGIHGNGTCICKDGFYGSECQFCSDP-NKYGH
KCEKRCRCVKGTCNNRVDSNGDCLPDTCQDGTFGHFCNFRAFPCGYLV-PVCDVRSFCQS
EIY---------------------------------------------------GESCIC
EDGYLYDGFG-CYEQDPCRDPD-RGGCSRNAECIKTGPGSHTCVCHRGWMGSGRDCKEIN
PCLLPSKGGCHGSATCLYVGPG---QNECECQKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQAVAPGAWSCVCQEGYE-GDGVL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGDVATELSFLPEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
AFNQWISKASLQPLLSSTSNLTVLVPSWRAIEDMDRDEKSFWLSWSDLPALIKFHTILGT
YGVADLQSLTSSDMLATSLPGGFLHLEKADGNVTIGGASIVDGDNVATNGMIHIIDKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLSGSLPNLLTRLNQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLASAIEAADSYTVFAPNNAAIEN
YIKEKKVATLGEDTLRYHVVLKEKLLKSDLHNGMHRESILGPSYHLGFFLRDQQLYVNEA
PINYTNVATDKGVIHGLGKVLGIQKNRCDNNETTV-VRGKCGKCLQ--RPICPPGTKPL-
---KTKCIYSLYFMGKRSVFIGCRQTCVRTVLTRECCAGFFGPECQACPGQRG-SACFGN
GVCMDGVNGTGACECGPGFHGTACETCVDAKYGVHCDQ--GAHASLSLQVSPPR----LQ
PPVLWV---LRLTITEDSCNGTCHTSANCLVSPDGTATCRCAAGFQGNGTICK----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRNGGCSSKADCKRTTPGSRMCVCKAGHTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCHQNAECTHT
GPNQAACNCLPTYSGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLKKNGGCSPYAICNHTGTGERTCTCKQNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1769)

CRGYIYEELPKNPQTSQYFFQLQEHGV

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RELAGPGPFTVFAPLSAAFSEDPQIKD--WHS
QGLMPQVLRYHVVACHQLLLENLKLTPNVTSLQGEGIVISVS-QDAVYINNQAKIISGNI
INTNGVVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PRNLLASPRDSMGRILQNLTTVAAKHG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2038)

GRFSKLLQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPQEQRDFLFSPDN--EDKLKGYLKFHVIRDSKVLAV
DLPRSASWKTLQGSELSVKCGAGS-DIGELFLNGQMCRIVQRELFFDLGVAYGIDCLLTD
PSLGGRCDSFSTFNVPGDCGSCLNTPR-CPRWTKPKGVKQKCSYRMM-PFRSVLEGCRNE
CTLVIQL-PRCCKGYFLPDCQACPGGPDTPCSNRGICQKVYSAEGQCRCDNGFNGTACEL
CWPGRFGPD-CQPCGCSDHGQCDDGISGSGLCLCESGWTGHLCDT---------------
-----------------RTAVSPVCTPPCSAHATCMENNTCECNLNYEGDGITCTVVNF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAQCSQKGTKVSCNCPKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GRHKCECKSHYSGDGLA

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQNNGDCAPD--ADCVDLHFQDTTAG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHSRS
PLGQYKLNFDQASLACAKEAAVMATYTQLSYAQKAGYHLCS-AGWLDSGHVAYPTAYASQ
KCGGGTVGIVNYGVRSNKSEMWDVFCYRMK--DVNCTCRPGYVGNGVSCNGNLLQVLMSN
PLLKNFL--------KEVLAYSNSSARGRVF-LKHLTDLSIHSTLFVPPNNGLWENETLS
GRDIEHHLASVSAIFYDDFVNGTT----LRTRLGSQLLVTASRDQPDL------KEIWFV
DGRAILEWDIFASNGVIHIISRPLKAPPAPT-STHAGLGTGIFFAIILVTGSIALAVYSY
FRLNRR-AIGFRRFESDE-NVDVAALSKQPPENISN-PAYESWS-SAPP----PPPCEPL
SPSLSQ---ELDSS--DPLGAGTL---

---------TCQHLSVSIL--LWVVKNILNRNNTLNQMKKQCDQKLLIRMKTECVPCSLN
LETQCPAGYTKITNG-TGIPDCR-YYLEIKTHTLSFPGCRHACIKEFEQPECCQGHWGPD
CM-----------------A

PF00008 // ENSGT00760000119025_0_Domain_0 (141, 177)

CPGGAASPCNGRGRCSEGI-KGDGTCICQKGFGGTACEKC
AEENLFGPQCTSVCNCVHGVCNSGITGDGRCTCLSGYQGLSCDQPIA----ECEALRCPA
NSRCTISDEDGRRLQCTCLPNYHGDGTHCEPINP

PF00008 // ENSGT00760000119025_0_Domain_2 (275, 309)

CSKKVCDPNANCIYLGPNHHKCACQE
GYKGDGQVCLPIDPCQAIYGNCLAQSTVCIYDGPGKSHCECKEH--YTNFVPGKGCSMID
LCETNNTCHKKAKCSMVAPGQITCTCQRGFVGNGFVCYGSIMERLQDLNTEVGGRWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

KL
TSALSLME-NVYEWPLSNLGPFTVLVPT-NRGLKGINIKDLLSNKLKAQYFVKLHIIAGQ
LDTSSLNN--TNVIYTLTGKSGEISRGEKDNQLRIRIQGGKRKGKLLQGDIIASNGILHI
VDKSMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

NIEPTFESNKEETIMSVLQDNE

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

KYSQFTSLIE----KTGLGMDLQQ--ENRPYT
VFIPSNGALNNMKAEAMDYLLSAEGSWKLLELVRYHIVSNAELEAASLISIEHIRSMAKQ
FLHFNRTSTGQVLVSGEEMEETDIVAKNGRIHTLAGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPTI--IPILPHRCDETRSQI
TMGICASCFS-QALTPCPADSKPLPFLKKRCI----IEGPTFPKTGCARYCNVITKEPKC
CRGFFGPNCS-P

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSKPCSGNGQCMDGLDGNGTCICAEAFQGSR

ENSGT00760000119025_0_Linker_6_7 (828, 884)

CQFCSDP-GKYGP
QCDKKCLCVYGKCDNRIDSDGTCLPGSCRSGYTGKLCDKPVVP

PF00008 // ENSGT00760000119025_0_Domain_7 (884, 972)

CEPSL-RLCHAHADCQL
SNG---------------------------------------------------AVSCVC
KPGYEGDGMT-

ENSGT00760000119025_0_Linker_7_8 (972, 978)

CSKVDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CASLY-PGGCNINAECIQTGPGEYLCACQAGWTGDGQDCSAIN
NCLLPSVAGCHENATCIYVGPGQQ-QNDCKCKDGFRGNGIECTPINS

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQNGKCHHL--
------------------ATCQFEPSHGWECVCPKGYE-GDGRT

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAADELSTLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAA
AFNQWVNEAEINSVLSTTSNLTILVPSPQAIENMDEDEKAFWMSKSNIPTLLKYHVLTGA
YSFADFQNLSSSDMLPTSLQSNFLHLSKENGNLTVEGAHIVAGDIASTNGIIHVIDKVLT

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PLRS--TVMPRLLARLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QYGLANEIEAANTYTVFAPNNDAIEN
YLSEKNISTLVEDQIRYHVLIDEKLLKNDLHNGMHRETMLGFSYHIGFFLHNSQLFINDA
PLNYANVATDKGIIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1485)

IKKNRCDINDTVI--TEKCRICSQ--PTSCPPGTKEIA
GQ-KKYCVFSESNMRMYTIQIGCQPKCAKTIITRECCAGFFGPQ

PF00053 // ENSGT00760000119025_0_Domain_13 (1485, 1542)

CQPCPGKAG-SACFGN
GVCMDGINGTGTCQCGAGFVGTACESCAEGKYGRNCDQ--VCACVHGKCSSGIDGDGSCE
CDVGWRGVTCESEIKEDACNTSCHTSANCLLLSNGTAYCKCAAGFTGNGTFCT----AID
ACETNNGGCSDKAECRKTTPGNRVCICNAGYTGDGVVCIEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLKGYSGDGKRCTYISLCSQNNGGCSEFAICNDTELTERTCTCRRNYIGDGF
KCRGNIYQELLRDS

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

NTSRFYFHLEALSIRDIAGPGPFTLFVPHTDVLNSNPQVRD--WLA
KGEMAQILRYHMVGCASLLYSNLKTIKNITSLHGDQIQITYS-QNSVYLNNKAEIIFSDV
VGTNGVIHIINQILV

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PSHIQDFPPGPK---KESLKMVAAKHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2041)

-YILFSNLLEK--NNLL
GLINDPIHKPVTLFWPTDTAIRGLPQEQQDFLFRKSN--TDKLVQYLKFHIIRDAEVLAY
QLPRSTSLKTLQGSNLTISCGDNT-EIGALFLNDRQCKIVQRQLEFDGGIAYGIDCLLTD

ENSGT00760000119025_0_Linker_18_20 (2041, 2123)

PSLGGRCDSFFAVEFMGYCASCFSGSK-CPPGTKPKEGIYRCTYE---TYGLRRDGCRRN
CSMLIHT-AKCCKGYFGPDCQA

PF07974 // ENSGT00760000119025_0_Domain_20 (2123, 2158)

CPGGPETPCNNHGSCDDGYAGTGECRCDSGFNGTS

ENSGT00760000119025_0_Linker_20_21 (2158, 2174)

CEL
CLPGRYGSN-CKL

PF07974 // ENSGT00760000119025_0_Domain_21 (2174, 2203)

CECKNNGQCEEGYSGTGRCFCETGWTGRL

ENSGT00760000119025_0_Linker_21_23 (2203, 2245)

CET---------------
-----------------KLALLPV

PF00008 // ENSGT00760000119025_0_Domain_23 (2245, 2274)

CSPSCSANAVCMENNTCQCKPLYNGDGIT

ENSGT00760000119025_0_Linker_23_24 (2274, 2280)

CIAEDL

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCHKAAECTQLGVKVFCSCQKGYKGDGFT

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CLPINP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGFNGGCHEHAICTVTGP
DKRKCDCKNNYIGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2393)

CSVMQLPLNRCLQDNGQCHPD--ADCADLHFQDTT

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

VGVFHLRS
PQGQYKMTYEKAKEACANESATIATYNQLLYAQKAKYHLCA-AGWLDNERVGYPTAFSSP
NCGAGYVGIVDYGRRVNLSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2519)

YREK--EVNCTCKPGYVGDGLSCSGNLLQVLM

PF02469 // ENSGT00760000119025_0_Domain_27 (2519, 2667)

SF
PTLTNFL--------SKIMAYSNSSRRGKAF-LRYLTDLSVHATLFAPNDSGLRENQTLT
GRDIEYHLSNATIMFYDDLTNGTT----LLTRAGEKLLITNTRGQEYPASTTEQNEIRYV
DGSAIVEWDIIASNGIIHVISEPLKAPPAPV-PFHATTGTGIFFGICLVIGVMAFIGYSY
LRFRRK-NTGFQHFKSKD-DTDVTSLDKSQPSNITN-PSYESSSALSPP----EPTYDLF
SDSDDQ---QLVMS--GPYDQN-----

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGHWGPD
CI-----------------ECPGGAESPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----QCAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPRAHCTYLGPNRHSCTCQE
GYRGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
ICKTNNLCHRNANCTTVGPGQTQCMCRKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DEGLKEFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKNKVKIIQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCAESLAGNGTCICKEGFQGSQCQFCSDP-NKYGP
QCNQKCPCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SSG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQLTLSATSNLTVLVPSQQATKDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIAN
YIREKKVPSLKEDVLRYHVVLEEKLLKNDLHNGMHRKTMLGFSYFLGFFRHNNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTRPLS
NE-KRRCIYTSYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCLPCPGNAQ-NVCFGN
GICLDGVNGTGVCECEEGFSGTACETCTEGKYGTHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGMCHTSANCLPNSDGTASCKCAAGFRGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYMGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGNGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGNIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLEHLILISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGSCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYTGTGMCKCNTGFNGTACEM
CWPGRFGPN-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANETATMATYSQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCSCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMSLTHTGLGAGIFFAVILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESAT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

MGRSKLFLSMLL-P-LIPLFLGLVVQNACSPTEGPEL-AKRCDKKSTLTIKTECQSCSAN
FAVKCPDGYIKVTSGSAGVRDCR-YSLDIQSYVLAIPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARAPCGGRGVCDEGM-EGTGSCSCQAGFSGTACEAC
ATDNVFGPNCSAVCSCVHGVCNSGLNGDGTCECLSAYRGPKCDKPIP----ECATLLCPE
NSRCSPSSKDETKLQCKCLPNYEGDGHNCRPTNGFKNQLCHPH-SCSYLGQIAHLH-MPK
GYKRDGQVCLPVGPCQTELWKPPE--STVNYDGPGQSHCECKEH--YRNFVPGVGCSMTD
ICESNNPCHKNANCSTVSPGKTKCTCQKGYVGDGLNCYGNIMQRLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

QL
TSFISILD-RTYAWPLSNLGPFTVLLPS-DKGLKGVDVKELLMDKEAARYFAKLHIIAGQ
MSMEQMYH--LDTFYTLTGKSGEIFNKDKDNQLKLKLHGSK-VVKIIQGNIVASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKTEPTFASNPQQTIMAMLQP--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

YGRFRSLLE----KTNVGQILDEG---GPYT
IFVPSNEALSNMKADILDYLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTPHIRSMANQ
IIKFNITSKGQILANNVAMDETEVAAKNGRIYTLTGVLIPPSI--LPILPHRCNETKIEL
KLGTCVSCST-KHWSKCPADSKPATIFS-SCFYSSRVRNL---KSGCARYCNVTVEIPRC
CKGFFGPDCT-PCPGGFLTPCSGNGQCMDGLAGNGTCICQDGFQGSMCQFCSDP-NRYGP
RCNRTCLCVHGTCDNRLDSDGACLSGTCREGTAGRFCDKQTSACGPYV-QFCHIHASCEY
SNK---------------------------------------------------TASNPP
GPGDEIE------------------TQLQKAECIQTSTGTYSCVCQQGWTGNGRDCVGIN
NCLLPSSGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTEKCHPL--
------------------ATCQSTSSGVWSCVCREGYE-GNGVL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNVLMELSFLPEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSVLSTTSNLTVLVPSRRAFEDMDQNEKSFWLSRNNIPALIKYHILLGK
YGVADLQALSSPHMLATSLQGNFLQLDKADGNITIEGASIVDGDNAATNGVVHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPSLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

GYSIFRGYII----HYNLASAIEAADAYTVFVPNNEAIEN
YIREKKATSLKEDILRYHVVLGEKLLKNDLHNGMHRETMLGFSYLLAFFLRNDQLYVNEA
PINYTNVATDKGVIHGLEKVLEIQKNRCDNNDTII-VRGECGKCSQ--QAPCPLETKPLR
ET--RKCIYSIYFMGKRSVFIGCQPQCVRTIITRACCAGFFGPQCQACPGRGQ-NVCSGN
GFCLDGVNGTGTCQCGLGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCSQGPLGDGSCD
CDVGWRGVKCDMEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFRGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSTKADCKRTTPGNRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRNAECTQT
GPNQAVCNCLPKYTGDGKVCSLINVCLTNNGGCSPFAFCNT-EQDQRICYRAADYCGAGC
VCGGEVCGELPKNPSTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFAPLSSSFNHEPRIKD--WDQ
QGLMSQVLRYHVVGCQQLLLDNLKVTTSATTLQGEPVSISVS-QDTVFINNEAKVLSSDI
ISTNGVIHVIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKNLLITPKDALGRVLQNLTTVAANHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSKLIQD--SGLL
SVITDSIHTPVTVFWPTDKALEALPPEQQDFLFNQDN--KDKLKSYLKFHVIRDSKALAS
DLPRSASWKTLQGSELSVRCGTGS-DIGELFLNEQMCRIIQRGLLFDVGVAYGIDCLLMD
PTLGGRCDTFTTFDIPGECGSCIFTPR-CPLKSKPKGVKKKCIYNPL-PFRRNVEGCQNL
CTLVIQT-PRCCHGYFMPDCQACPGGPDTPCNNRGMCRDLYTPMGQCLCHTGFNGTACEL
CWHGRFGPD-CQPCSCSEHGQCDEGITGSGECLCETGWTGRFCDT---------------
-----------------PTAVIPVCTPVCSVHATCTENNTCVCNLNYEGDGLTCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCKKGYKGDGYSCIEIDPCADGVNGGCHEHATCRMTGP
GKQSAECKTSTRGRQWTGEPEQLPLDVAYSDNETVATPDCQAVQTLHFQDTTVGVFS-TL

PF00193 // ENSGT00760000119025_0_Domain_26 (2401, 2487)

PLGRYKLTFDNAK-SCAKEAATIATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTTYASQ
KCGANVVGIVDYGSRANKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAFSKSSARGQAF-LKHLTDLSIRGTLFVPQNSGLPGNKSLS
GRDIEHHLTNVNVSFYNDLVNGTF----LRTMLGSQLLITSSQDQLHQ-------ETRFV
DGRSILQWDIIAANGILHIISEPLRAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSY
FRGKQR-ERGFSKFQSEE-DIDVLAFGKQQPKNIAN-PLYETSA-PAPP----ESSCDPF
TDPGEQ---DLEDS--DPLGALRS---

-----MGRSKLL-P-LILIFLGLLMQNACSPTEAPEL-TKRCDKKSTLIIKTECQSCSIN
NAVKCPDGYIKITNGTIGVRDCR-YSLNIHSYVMDIPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARAPCGGRGVCDEGM-EGTGSCSCRAGFRGTACENC
AAEDVFGPNCSAVCSCVHGVCNSGISGDGTCECLSAYRGPRCDKPIP----ECAALLCPE
NSRCSPSSKDKTKLQCKCLPSYEGDGQTCKPINPCLKNVCHPHASCSYLGPNRHSCVCQK
GYQGDGQVCLPVDPCQTSYGNCPTKSTVCRYDGPGQSHCECKEH--YRNFVPGVGCSMTD
ICESKNPCHKNANCSTVSPGQTQCTCQTGYVGDGLNCYGNIMQRLKELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

QL
TSFISILD-RTYAWPLSNLGPFTLLLPS-DKGLKGVDVKELLMDKEAARYFVKLHIIAGQ
MSTEQMYN--LDTFYTLTGKSGEIINKDKDNQLKLKLYGSK-IVQIIQGNIVASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKIEPTLESNPQQTIMTMLQP--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

YGKFRSLLE----KTNVGQALEEGGIDEPYT
IFVPSNEALSNMTAGVLDYLLSPEGSRKLLELVRYHIVAFTQLEVTTLVSTLHVRSMANQ
IITFNISSKGQILANNVAVDETEVAAKNGRIYTLTGVLIPPSI--LPILPHRCNETKREM
KLGTCVRCFM-KKWSKCPTNSEPTEIFTNKCFYGSRAWNL---KTGCARYCDVTVEIPRC
CKGFFGPDCN-PCPGGFMNPCSGNGQCIDGLGGNGICICKDGFQGSRCQFCSKP-NRYGP
QCNRTCLCVHGTCDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPYV-QFCHIHATCEY
SNE---------------------------------------------------TASCVC
NDGYEGDGTL-CSKKDPCLGST

PF12947 // ENSGT00760000119025_0_Domain_8 (983, 1016)

SRGGCSPNAECIQTSTGTYSCVCQRGWTGNGRDCVEIN
NCLLPSSGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQIEKCHPL--
------------------ATCQYTSSGVWSCVCQEGYE-GNGVL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNVLMELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSMLSATSNLTVLVPSLQAIKDMDQNEKSFWLSRNNIPALIKYHTLLGT
YRVADLQTLLPSHMLATSLQGSFLRLDKADGNITIEGASFVDGDNAATNGVVHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPSLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLASAIEAADAYTVFVPNNEAIEN
YIREKKATSLKEDILRYHVVLGEKLLRNDLHNGMHRETMLGFSYLLAFFLHNDQLYVNEA
PINYTNVATDKGVIHGLAKVLEIKKNRCDNNDTVI-VRGKCGKCSQ--QTLCPLETKPLS
ET--RKCIYSIYFMGKRSVFIGCQPQCVKTIITSACCAGFFGPQCQACPGKGQ-NVCSGN
GFCLDGVNGTGTCECGQGFNGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPGGDGSCD
CDVGWRGVKCDSEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTIPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRHAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAFCNHTEQDQRTCTCKPDYTGDGI
V

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIHGELPKNPSTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFVPSSDSFNREPKLKD--WDE
QGLMSQILRYHVVACQQLLLENLKVITSATTLQGEPISISVS-QDTVLINKKAKVLSSDI
ISTNGVIHIIDTLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLITPRGASGRVLLNLTTVAANHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSKLIQD--SGLL
RVITDPMHTPVTIFWPTDKALQALPQEQQDFLFHQDN--KDKLKAYLKFHVIRDTMALAS
DLPRSASWKTLQGSELSVRCGTGS-DVGELFLNGQMCRIIQRRLLFDGGVAYGIDCLLMD
PTEGGRCDTFTTFNIPGECGSCFSTPR-CPLQSKPKGVRKKCIYKPL-PFRRDEEGCQNL
CTLVVHV-PRCCSGYFMPDCQACPGGPDTPCNNRGMCYDLYKPTGQCQCHTGFNGTACEL
CLPGRFGPD-CQPCGCTEHGQCDEGITGSGQCLCEVGWTGRFCDA---------------
-----------------PTVVIPVCIPACSVHATCMENNTCVCNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDTCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GKQKCECKSHYVGDGWD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCH-PDA-NCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACAKEAASIATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTIYASK
KCGANVVGIVDYGTRTNKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCNGNLLQVLMSI
PSLTNFL--------TEVLVFSRSSAQGRAF-LKHLTDLSISGTLFVPQNSGLPKNKSLS
GRDIEHHLTNVNVSFYDDLVNGTV----LKTRLGSQLLITSSQDQLHQ-------ETRFV
DGRAILQWDIIASNGLLHIISEPLKAPPIATTAAHSGLGTGIFCAVVLVIGVIALVAYFY
FRLNQR-TTGFRRFETED-DIDALAFGKQQPESIAN-PLYEAST-PAPP----EPSCDPF
TDAGEQ---ELENS--DPLGALRS---

--------TMLL-H-SIILFLGLAVPNFCSRTATTQQ-GKRCDKKSLLIHRTECRSCFLX
XXXXXXXXXXXXXXX-XXXXXXXXYTLEIKTYFLSLPGCRHICRRDYLQPQCCPGHWGPD
CM-----------------ECPGGAMSPCSGRGTCDEGM-EGNGRCACQEGFGGTTCEIC
ADDNLFGPNCSAVCSCVHGVCNSGIDGNGTCECYSAYTGTNCTKXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFHCECKEH--YYNFVPEVGCSVTD
ICETNNPCHRNARCATIAPGQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_4 (418, 547)

XXX
XXXXXXXX-KVYAWPLSNLGPFTMLLPT-DKGLKGFSVQQLLTDTKAAEYFVKLHIIAGQ
MSTNHLNN--TDTFYTLTGKSGEVFNRDKDNQLKLKLYGGKKKVKIIQGNVIASNGLLHI
IDRSMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KLGPTFESNTEKTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGYSFGQGVFRGPYT
VFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIIPFVQLEVAILIAYANVRTMANQ
LIHINTTNNGQILVNGVAMEEIDVAAKNGQIYTLNGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--IPILPHRCDEIKREM
KLXXXXXXXX-XXXXXXXXXXXXXALYRPKCIYSSRQSGP---TNGCARYCNATVKIPKC
CRGYYGPDCN-L

PF07974 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSNPCSGNGQCVDGIGGNGTCICEDGFQGSKCQFCSDP-NKYGP
RCDKKCLCARGTCDNRIDSDRACLAGTCRDGSDGKFCNKQAHSCGPYM-QFCHIHAACVY
SNG---------------------------------------------------TASCIC
KAGYEGDGTL-CSEADPCSELT-PGGCSRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXXNECECKKGFQGNGIDCEPVNSCLEQTKKCHPL--
------------------S-CQSTSSG-TSCVCPEGYE-GDGLVCYGNAAVELSLLL

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAT
IFNQWITDAALRSMLSATSNLTVLVPSQQAVEDMDPGDKTFWLSKSNMPALVKYHTLLGI
YGMADLQSLSSPDLLATSLQGTFLHLEKVNGNITIEGASIIDGDIAATNAVIHVINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PRRSLTRSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

GYSIFRGYII----QYNLASVIEAADAYTVFAPDNNAIET
YIREKKAATLEEDIVKYHVVLEQKLLKNDLHNGMHRETMLGFSYLLGFFLRNDQLYVNEV
PINYTNAATDKGVIHGLVKVLEIQKNRCDNNDIVI-VRGNCGKCLQ--QLHCPLGTKQLX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXMRECCTGFFGPECQPCPGKAG-NACFGN
GICLDGANGTGVCQCGEGFNGTACESCYEGRYGIHCDQ--VCPCVHGRCNQGPSGDGSCE
CDVGWRGVHCDIEITTDNCNGTCHSSANCLLNSDGTASCKCAAGFQGNGTVCK----AID
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CAISHGGCSAKADCRRTTPGRRLCVCKAGYTGDGIVCQDINPCLEH-GGGHRNAECTQT
GP-QAVCNCLPTYTGDGKICTLINICLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_17 (1776, 1876)

XXXXXXXXXXXXXXXXXLEH--WDQ
QRVMSQILRYHVIACHQLLLENLKSTPNATSLQGESIAISVS-QDTVYLNNKAKIISSDI
ITTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLIVTPRDAFGRILQNLTTVAKKHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YTKFSNLIQD--AGLL
TLITDPIHVPVTLFWPTDRALQALPAQQQDFLFNQEN--NDKLKEYLKFHVIRDSKVSAV
DLPRSAAWRTLQGSDLRVNCGPSS-DAGALFLNGQTCRIVQRELVFDLGVAYGIDCLLID
PTLGGRCDTFASFNALGSCGSCTNTPK-CPRYTKPKXXXXXXXXXXXXXXXXXXXX---X
XXXXXXXXXXXXXXXXXXXXXXCPGGPDNPCNNHGTCQEAFWGTGHCLCHTGS-GTACEX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX---------------
----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCDKVAKCSQKGTLVSCSCPKGYKGDGYSCMAIDLCADGLNGGCHEHATCKMTGP
GKRRCECKSHYVGDGLNCETEQLPIDRCLQDNGQCHAD--ADCSDLHFQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX---XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLS
GRDIEYHLASVNIILYNDLVNGTT----LQSRLGSQLLITSSEDQSHL-------ETRFV
NGRAILQWDIFASNGIIHIISGPLKTPPTPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXSEE-DINAAALGKEQPENISN-PVYDNTA-SAPP----EPSYDPF
VESDEQ---QLMSS--NLLGGL-----

---------------------------------------RRCDKKTFISSKTLCMSCALN
YKTNCTEGAKKITSG-SGLRDCR-FLWACFSYLLILVLARDAPTPRFTSPLVCPKYFGMN
PI-----------------HCPGGASSVCNNRGTCSDGI-QGNGSCTCQEHFGGTACETC
SGNNLYGADCNKVCDCVHGVCKSGISGDGTCSCYSGYDGPKCDQPLK----ECAALQCRE
NTRCVNSST--GALECRCMPDYEEKGDKCEPINP

PF00008 // ENSGT00760000119025_0_Domain_2 (275, 309)

CSQRICHEAAECIYLGPNRHRCSCNI
GYKGDGAVCLPIDPCQENFGNCPTDTSICKYDGPGRSHCECKEG--YINFQPGLGCQLID
VCTVKNPCSKNANCTTIAPGQTECVCKKGYIGDGTVCYGNILERMKELNTLP-GQWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 548)

KL
SIAISLFGKEVYSWPLSTLGPFTVLVPI-NKGIRGKNVKNLITDKENTLYFIKLHIIAGQ
WSSELFNT--TDLIYTLTGKSGEITSGEVDDEIKIRIHGSKKKGKILQKNIIASNGILHI
IDRAMDY

ENSGT00760000119025_0_Linker_4_5 (548, 569)

VEPTLESNPKETIMSILQVNG

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYNRFKLLLE----KANLGPDLEKD---GPFT
VFVPNNEALSAMENGTLDYLLSSEGSRKLLELMRYHIVQSAQLDVANIISATHIMSMANQ
LIQFNTTKKGQILVNGEEVEEADVAAKNGRIYTLDGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--LPILPHRCDESKYET
QLGSCVSCSSVLFLSSCPLGTEPLNIFTQKCKYRNTIMGNDYERHGCSRYCNVTVKVPTC
CKGFYGRDCR-P

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFINPCSRNGECMDGWNGNGTCICDIGFNGAD

ENSGT00760000119025_0_Linker_6_7 (828, 884)

CRRCTDN-NKYGL
RCDKKCLCIHGRCNNHVDSDGSCLPSSCASGYSGKLCDRKTIP

PF00008 // ENSGT00760000119025_0_Domain_7 (884, 972)

CGPLV-TFCHAHADCEY
SDG---------------------------------------------------TPRCVC
KSGYEGDGTY-CREANPCISSD-REICNVNADCLPVGPVNHKCVCRAGWTGDGLDCSEIN
NCLLDNKGGCHPNATCVYIGPG---QSDCECNKGFRGDGIDCEPVNACLEKAEKCHFL--
------------------ASCKKMATGFWECVCGEGYE-GDGTICYGTAGEVVAALQ

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAS
EFYRWIYDETIKNLLSQTSNVTVLVPSRQAFEIMRKEDKAYWMTKENVPPLLKYHILSGI
YSVDSLKNLSSSDLLATSLHSNFLKVSNENGTTSINGAKFMVGDIAAKNGFVHIIDKVLT

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PNQLMVGSDPDFMTRLGQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRSYVI----EYQLAKEVEAADSYTIFAPHNDAINS
YIRSKSPVTVDEDTVRYHIVLGQKLLKDDLHNGMHRETLLGFSYQLGFFIHGEQLYINDA
PVNNTNIYTDKGVIHGVGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1488)

IQKNRCDLNDTSL-ALSKCGECLT--TPACPPGTQPIA
SE-KKSCIFTKYYFGKRFVYIGCQVQCAKTIITRECCPGFYGQQCLS

PF00008 // ENSGT00760000119025_0_Domain_13 (1488, 1524)

CPGKGG-NPCFGN
GVCMDSINGTGTCQCKDGYIGTA

ENSGT00760000119025_0_Linker_13_14 (1524, 1622)

CETCVKGKYGPRCDQ--ECYCINGKCSEGINGDGSCN
CDVGWRGVKCDTAITEDKCNKSCHTSANCIVNADGIARCQCASGFQGDGTVCS----AVN
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CASNNGGCSDNAECRTTTPGNRICVCKWGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CIEVDP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CATNNGGCHKFAECTKT
GANQSACNCLQRYSGDGIK

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CDPINP

PF00008 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLQKNGGCSAFAVCNHTGPAERTCECKSDYIGDGI
D

ENSGT00760000119025_0_Linker_16_17 (1742, 1755)

CKGTIYQELPKNR

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

DTSTFYNQLQLNQINDLSGPGPFTVFVPSTSAFNDESMIKE--WTA
KGVMEQVLLYHIVSCAQLTKDDLTSIATVTSLQGDSLTFTYSQQDSVLLNGNAKIISSDT
IMTNGIVHIIDKVLV

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKNMQNFNKEASKIVLDSLTKVAETHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YSAFSKLLQD--TDIL
TLINDPIHQPVTIFLPTDNALKSLPKEQNDFLYDSQN--KEKLLQIIKYHVIRDAKIYTT
DLVRKGSIKTLQGTDLSVKCADKE-SYGDVLLDDRQCKLVQRQLMFNGGIAYGIDCLLTP
SSVGGRCDNMVTFELMGSCGRCSNVPK-CPSGSKPKPDKVKCTYNL--SSRRTLDGCRYD
CSMVVWM-TKCCSGFFGRDCQGCPGGPETPCNNHGLCDDGHSGTGECRCNPGFNGTACEL
CLPGRYGPD-CKP

PF07974 // ENSGT00760000119025_0_Domain_21 (2174, 2203)

CDCTEHGQCDGGSSGSGKCSCDSGWTGKRCET---------------
-----------------KLVLPPVCTPACSSNAVCKEKNMCQCKKFYEGDGRTCNVVNL

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCDSNAKCSQSGVKVTCSCLKGYKGDGNVCTPIDPCADGFNGGCDEHAICTMTGP
DKRKCECKDQYIGDGLSCEVKKLPINRCLQDNGQCHAD--ALCNDLHFQDST

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

VGVFHLRS
SKGVYKYNYSEAMKACNDETATIATYNQLSYAQQAGFHLCA-AGWLDGVRVAYPTTYSNQ
NCGSGFVGIVDYGPRVNLSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2540)

YRVKVS-INNIKHVYYWV----IYFSYLVIIMCY
SNIYFFF--------QEIL

PF02469 // ENSGT00760000119025_0_Domain_27 (2540, 2667)

VYSNTSVKGKEF-FNYLTNLSVQATLFAPSNDGLNENQTLS
GRDIEYHLANVSMFFFEDLSNGTT----LQTRIGHKLLISFDNDPASK------TPTRYV
DGKPILQWDIIASNGIIHTIAEPLTAPPEPL-ALHAGHGAGIFFGIVLIVGLLALAVYYY
KKFNRK-DFQFQFQQFNEYDEKPIVSELDRPSNIAN-PMYESSTATSLPETSTEPSFHPF
SDSDEQ---QLENQENLAFS-------

RRSSEYFLTMLQ-S-VILFFLGLVVQNLCFLSETAEQ-GKRCDKKSLLTIRTECQSCSVN
FGMKCPDGYTKITNGTPGIRDCR-YTFEVRAYSLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCSGRGRCAEGM-EGNGSCLCQEGFSGTACEIC
AADNVFGPNCSAVCSCVHGVCNSGIHGDGTCECYSGYTGRNCDEPIL----ECAALLCPE
NSRCSPSSKDEIKLECKCLPNYKGDGKHCEPINPCSQNICHPHARCTYLGPNQHRCTCQE
GYRGDGQVCLPVDPCQVNFGNCPTESTVCRYSGPGQAYCECKQH--YRNFVPGVGCSMTD
VCESNNPCHTHADCTTIAPGQTKCTCRKGYVGDGSTCYGNIMELLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVNEFLLDNKAAQYFVKLHIIAGQ
MSTEQMNN--TDTFYTLTGKSGEIFSEDKDNQLKLKLYGSKKTVKIIQGNILASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKVVPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTSVGHALNEDGVGGPYT
VFVPSDEALNNMKDGTLDYLLSSEGSRKLLELIRYHIVPFTQLEVATLISTPHIRSMANQ
IIRFNTTNNGQILANGVALEEMEVAAKNGRIYTLTGVLIPPSI--IPILPHRCDETKREM
RLGTCVSCSL-VYRSKCPADSEPTTLFVHKCIYTGRIRSP---KNGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCTDGLDGNGTCVCQDGFRGTQCQFCSDP-SKYGP
RCDTTCPCIFGTCDNRIDSDGACLPGSCRNGSAGRFCHKQTSACGPYV-QFCHIHGTCEY
SDG---------------------------------------------------TASCVC
KPGYEGDGSF-CVEMDPCSGSI-PGGCSRYAECIRTGRGTHTCVCREGWTGDGRDCSEIN
PCLLPSAGSCHHNATCLYVGPG---QNECECKKGFQGNGIDCEPITSCLEQTEKCHPL--
------------------ATCQLTSSGIWSCVCQEGYE-GDGLLCYGNAAVELSFLSAAA
V

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNQWINNASLQHLLSTTSNLTVLVPSRQAIADMDQEEKAFWLTKSNIPVLIKYHTLLGT
YGVADLQALSPSDMLATSLQGNFLQLVKADGNITIEGASVIDGDNAATNGVIHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSSFRGYII----QYNLATAIEAADAYTVFAPNNDAIES
YIREKKVTTLEEDILRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLHDDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDINDTTI-VRGKCGKCPQ--PPICPFGTKPLG
QE-MRRCLYTIYFMGRRSPFLGCQPKCVKTVITRECCAGYFGPQCQPCPGKPE-NVCFGN
GICLDGVNGTGVCECGRGFSGTACETCAEGKYGIHCDQ--VCTCVHGRCNQGLLGDGSCD
CDVGWRGVKCDSAITKDNCNGTCHTSANCLLNLDGTALCKCAAGFQGNGTICT----AIN
ACEISNGGCSAKAVCKRTTPGSRVCVCKAGYTGDGIVCIEINPCLENHGGCHRHAECTQT
GPNQAVCNCLPNYTGDGKVCTLINVCLTNNGGCSEFAICNHTGQDERTCTCKPDYVGDGF
TCRGNIHQELPKNPKTSQFYFQLLEHS

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1876)

VRDLVGPGPFTVLAPLSAAFDEEPQIKD--WDK
GGLMPQILRYHVIACHQLLLENLKLTPNATSLQGESLVISVS-QDMVLINNKARIISSDI
LCTNGIIHVIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLLITPKDASGMILQNLTTVAMNHG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YGKFSNLIQD--SGLL
SVITDPIHTPVTLFWPSDQALQALPREQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPKFAPWKTLQGSELSVKCGAGS-DIGDLFLNSQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDVSGNCGNCIFTPS-CPKWTKPKGQKQKCLYD-L-PFKRNLEGCRQL
CTLVIQL-PKCCKGYFWPDCQACPGGPDTPCNNRGICLDPYSPSRQCQCNSGFNGTTCEL
CWPGRFGPD-CQPCGCSDHGQCDDGITGSGECICETGWTGRFCDT---------------
-----------------QTALAPVCTPPCSAHATCKNNNTCECNLNYEGDGITCTVVDFC
KQNNGGCAKVAKCSQKGTKVSCSCQKGYQGDGHSCTAIDPCADGLNGRCHEHATCKMTGP
GKHKCECKSHYVGDGLDCEPEQLPIDRCLQDNGQCHAN--ADCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAREACAQEAATMATYNQLSYAQKAKYHLCS-AGWLDSGRVAYPTSYASQ
NCGSGIVGIVDYGPRNNKSEMWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------KEVLVYSNSSARGRAF-LKHLTDLSIRSTLFVPQNGGLGENETLS
GRDIEHHLSNINIFFYNDLVNGTI----VHTRLGSQLLITSSQDQRQL-----E--TRFV
DGRAILQWDIFASNGIIHVISKPLKAPSIPGTPGHTGLGTGVFFAIILVIGAIALAVYSY
FRLNRR-TIGFQHFESEE-DIDVAALGKQQPENISN-PMYESTT-SATP----EPSYDPF
TDPADQ---LLDSS--DPLGAL-----

--------IMLQ-Y-LVIFCLGLVVQNFCFSAETAGQ-TRRCDQKSLLTIRTQCRACFLN
LEVNCPDGYTKITNGTVGVRDCR-YTFEIRTYSLLLPGCRHICRKEYLQPRCCPGHWGPD
CT-----------------ECPGGAGFPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGHSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPTCDKPIP----ECAALLCPE
NSRCSPSSEDETKLECKCLPNYQGDGKSCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQRNFGNCPTNSTLCKYDGPGQSHCECKEH--YHNFVPGVGCSMTN
ICESNNLCHKNANCTTIAPGQTKCTCQKGYVGDGFTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFISILE-KAYAWPLSNLGPFTVLLPT-DSGLKKFSANDLLVDIKAAQYFVKLHIIAGQ
MSTEYMNN--TDTFYTLTGRSGEIFNSDKDNQINLKLYGGKKKVKIIQGDLIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNLEPTFESSNEQTIMTMLQT--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEEGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHVRSMANQ
LIQFNTTDNGQILANNVAMEEIEITAKNGRIYTLTGVLIPPSI--IPILPHRCDETKREM
KMGTCVSCAL-VYWSRCPANSEPTALFTHRCVYSSRFRSL---KSGCARYCNGTVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLSGSGTCLCEEGFQGSRCQFCSDP-NKYGP
RCSKKCLCIHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSETDPCTGLT-PGGCSRNAECIRTGTGTHTCVCQPGWTGNGRDCVEIN
NCLLPSEGGCHSNATCLYVGPG---QNECECKKGFRGNGIDCEPITSCLEQTRTCHPL--
------------------ANCQFTASGVWSCVCQEGYE-GNGFLCYGDAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPSLIKYHTLLGT
YRVADLQTLSSSDMLATSLPGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRALLGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLAHAIEAADAYTVFAPNNNAIEN
YIREKKVMSLEEDILRYHVVLEEKLLKNDLHNGMHRGTMLGVSYLLGFFLRNDQIYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNYTTI-VRGKCTACST--KQLCPFGAKPLD
NE-IKRCIYTMYFMGKRAPFIGCQPICVRTVITRECCAGFFGPQCQACPGNTQ-NICSGN
GICLDGVNGTGVCECGDGFKGTVCETCTEGKYSIHCDQ--ACSCVHGRCNQGLLGDGSCD
CDVGWRGVHCDEVIKKDDCNGTCHTSANCIL-TDGTPSCKCAAGFQGNGTICT----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTFINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICTHTEQGERTCTCKPNYLGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1767)

CRGSIYQELPKNPKTSQYFFQLQEH

PF02469 // ENSGT00760000119025_0_Domain_17 (1767, 1876)

SVKDLANPGPFTVFAPSSAAFDEEARVIE--WDK
QGLMPQVLRYHVIACHQLLLENLKLISNATSLQGEPVVISVS-QGTVYLNNKAKIISSDI
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1907)

PKNLLITPKDTSGRILQNLTTLATNNG--YI

PF02469 // ENSGT00760000119025_0_Domain_18 (1907, 2039)

KYSKLIQD--SGLL
SVITDPIHTPVTLFWPTDQALQALPAEQQDFLFNQDN--KDKLKQYLKFHVIRDAKVLAV
DLPIPAGWETLQGSELSVKCGTGN-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PILGGRCDTFAAFNTLGDCGSCFNTPS-CPKWSKPKGVKQKCLYN-L-SFRKKLEGCREQ
CIRVIQI-PMCCKGYFGRDCQACPGGAEAPCNNRGVCDDQYWATGECTCNTGFNGTACEM
CLPGRFGPD-CLPCRCSDHGQCDDGITGSGQCFCETGWTGPLCDT---------------
-----------------QAVLPAVCMPPCSVHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVAKCTQKGTKVSCSCQKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCQCKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--ANCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFTSQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLISF
PSLTNFL--------TKVLTYSNSSARGHTF-LQHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

RSTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITAGQDPSQQ------TEARFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVPSTHTGLGAGIFFAITLVIGAIALAAYSY
FRLNRR-TIGFQHFESEE-DINVAALGKQQPESISN-PMYESTT-SAPP----EPSYDPF
TDSDER---QLEGS--DPLGAL-----

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITSGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPD
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCLPSTEDENKLECKCLPNYRGDGKYCDPINPCLRK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH--YQNFVPGVGCSMTD
ICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKKKVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNLGHALDEDGVGGPYT
IFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP-NKYGP
RCNKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ASCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHDGMHRETMLGFSYFLSFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELTCPFGTKSLG
NE-KMRCIYTSYFMGRRTLFIGCQPKCVRTIITRECCAGFFGPQCQPCPGNAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
YGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPVVISVS-QSTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATNNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGR-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGVKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGIMGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLETGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASQDPLQP------TETRFV
DGRAIVQWDIFASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAYSY
FRINRR-TIGFQHFESEE-DINVAALGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSEER---QLEGN--DPLGTL-----

------------------------------------------------------------
-----------------------------------GLGCQHILWGDKIQPMTIVS-----
----------------------------------LSYRM---------------------
KQGHESPRFLSAACPCVHGVCNSGIHGDGTCECFSGYTGPNCDKPIP----ACAALFCPE
NSRCSPSSKDETTLECKCLPNYKSDGKSCEPINPCSQ

PF12947 // ENSGT00760000119025_0_Domain_2 (278, 309)

NICHPHAWCTYLGPNRHSCTCQE
GYHGDGQVCFPVDPCQVNFGNCPTDSSVCRYDGPGQSHCECREH--YHNFVPGVGCSMTD
VCESHNPCHRDARCTTIAPGQTKCTCRKGYIGDGSRCYGNIMERLRELNTEPGGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTLLLPT-DKGLKGFNVKELLKDNEAARYFVKLHIIAGQ
MNTEQMTTLQMKTFYTLTGKSGEIFNGDKDNQVKLKLCGGKKKVNIIQGNIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKVAPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNMGHALDEDGVGGPYT
IFVPSNEALNNMKDGALDYLLSSEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
VIRFNTTDNGQILANGVAMEETEVAAKNGRIYTLTGVLIPPSI--TPVLPHRCDETKREM
KLGTCVSCSL-VYWSKCPADSEPMVSGTNHLS------RIEFELKKQAG-----------
NESTWGSWPGLCCPNG-QGPCL-CSQCADGLDGNGTCICQDGFRGSQ-----YP-NKYGP
QCDKSK-CRFQSCLLL-LSPGPCSTATSRSTA--RVS-GASWLVGTFL-FITGISKVLG-
-SQ---------------------------------------------------T-----
AAGARLPGP-----TQNVSDRS-PGGARGFA------FLSSLLLCPHCWAL---------
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MGRSTFPLSTLL-P-LILIFLGLLVQNACSPTEAPEP-TKRCDKKSTLTIKTECQSCSIN
IAVKCPDGYLKITNGTVGVRDCR-YSLNIQSYVLAIPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARSPCGGRGVCDEGM-EGTGSCSCLAGFHGIACETC
AADNVFGPNCSAVCSCVHGVCSSGISGDGTCECFSAYRGPRCDKPIP----ECAALLCPE
NSRCSPSSKDETKLQCKCLPSYEGDGQNCKPINPCLKNVCHPHASCSYLGPNRHSCVCQN
GYQGDGQVCLPVDPCQTNYGNCPTKSTVCRYDGPGQSHCECKEH--YRNFVPGVGCSMTD
ICESKNPCHKNANCSTVSPGQTQCTCQKGYVGDGLNCYGNIMQRLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

QL
TSFISILD-RTYAWPLSNLGPFTVLLPS-DKGLKGVDVKELLMDREAARYFVKLHIIAGQ
MSTEQMYN--LDTFYTLTGKSGEIFNKDKDNQLKLKLYGSK-IVQITQGNIVASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKIEPTLASNPQQTIMTMLQP--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

YGKFRSLLE----KTNVGQTLEEGGIDGPYT
IFVPSNEALSNMTAGVLDYLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTLHVRSMANQ
IITFNISSKGQILANNVAVEETEVAAKNGRIYTLTGVLIPPSI--LPILPHQCNETKREM
KLGTCVRCFM-KNWSKCPMNSEPTAIFTNKCFYGSRTWNL---KSGCARYCDVIVEIPQC
CKGFFGPDCN-PCPGGFLHPCSGNGQCIDGLGGNGTCICEDGFQGSMCQFCSNP-NRYGP
RCNRTCLCVHGTCDNRLDSDGACLSGTCREGTAGRFCDKQMSACGPYV-QFCHIHATCEY
SNE---------------------------------------------------TASCVC
NEGYEGDGIL-CSKKDPCLRST

PF12947 // ENSGT00760000119025_0_Domain_8 (983, 1016)

SRGGCSPNAQCIRTSTGTYSCVCQQGWTGDGRDCVEIN
NCLLPSSGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPIISCLEQIEKCHPL--
------------------ATCQYTSSGVWGCVCQEGYE-GNGVLCYGNVLMELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSMLSATSNLTILVPSQQAIEDMDQNEKSFWLSQNNIPALIKYHTLLGT
YRVADLQTLLSSHMLATSLQGSFLRLEKADGGITIEGASIVDGDNAATNGLVHVIDKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPSLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLASAIEAADAYTVFVPNNEAIEN
YIREKKVTSLKEDILRYHVVLGEKLLKNDLHNGMHRETMLGFSYLLAFFLHNDQLYVNEA
PINYTNVATDKGVIHGLEKVLEIKKNRCDNNETII-VRGKCGKCSQ--QTLCPLETKPRS
ET--RKCIYSVYFMGKRSVFIGCQPQCVRTVITSACCAGFFGPQCQACPGKGQ-NVCSGN
GFCLDGVNGTGTCECGPGFNGTACETCIEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVKCDSEITRDNCNGTCHTSANCLLDPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTIPGSRVCVCKPGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRHAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAFCNHTEQDQRTCTCKPDFTGDGI
V

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIHGELPKNPSTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELAGPGPFTVFVPSSDSFNRETRLKV--WDE
QNLMPQVLRYHVVACQQLLLESLKVITSATTLQGEPISISVS-QDTVLINKKAKVLSSDI
ISTNGVIHIIDTLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLIITPRSASGRVLQNLTTVAANHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSKLIQD--SGLL
RVITDPMHTPVTLFWPTDKALQALPQEQQDFLFNQDN--KDKLKAYLKFHVIRDTQALAS
DLPRSASWKTLQGSELSVRCGTGS-DVGELFLNGQMCRIIQRRLLFDVGVAYGIDCLLMD
PTQGGRCDTFTTFNIPGECGSCFSTPR-CPLQSKPKGVRKKCIYKPL-PFRRDVEGCQNL
CTLVVHV-PRCCSGYFMPDCQACPGGPDTPCNNRGMCYDLYKPTGQCQCHTGFNGTACEL
CWPGRFGPD-CQPCGCSEHGQCDEGITGSGQCLCEAGWTGRFCDA---------------
-----------------PTVVIPVCIPACSVHATCMENNTCVCNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYKGDGHSCTEIDPCADGVNGGCHEHATCRMTGP
GKQKCECKSHYVGDGRDCEPEQLPLDRCLQDNGQCH-PDA-NCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACAKEAASIATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTIYASQ
KCGGNVVGIVDYGTRTNKSEMWDVFCYRMK--DVNCTCKAGYVGNGFSCNGNLLQVLMSF
PSLTNFL--------TEVLAFSRSSAQGRAF-LKQLTDLSISGTLFVPQNSGLPENKSLS
GRDIEHHLTNVNVSFYDDLVNGTV----LKTRLGSQLLITSSQDQLHQ-------ETRFV
DGRAILQWDIIASNGLLHIISEPLKAPPTAATAAHSGLGTGIFCTVVLVTGAIALAAYSY
FRLNQR-TTGFQRFESED-DIDALAFGKQQPESIAN-PLYETST-PAPP----EPSCDPF
THSGEQ---ELENS--DPLGALRS---

MARSKLLLGKLL-P-LILIFLGLLVQNACSPTEAPEL-TKRCDKKSTLTIKTECQSCSVN
IAVKCPDGYIKITNGTVGVRDCR-YSLKIQSYVLDIPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARAPCGGRGVCDEGM-EGTGSCSCRAGFRGTACENC
AAEDVFGPNCSAVCSCVHGVCNSGISGDGTCECLSAYRGPRCDKPIP----ECAALLCPE
NSRCSPSSKDETKLQCKCLPSYKGDGQTCKPINPCLKNVCHPHASCSYLGPNRHSCVCQK
GYQGDGQVCLPVDPCQTSYGNCPTKSTVCRYDGPGQSHCECKEH--YRNFVPGVGCSMTD
ICESKNPCHKNANCSTVSPGQTQCTCQKGYVGDGLNCYGNIMQRLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

QL
TSFISILD-RTYAWPLSNLGPFTVLLPS-DKGLKGVDVKELLMDKEAARYFVKLHIIAGQ
MSTEQMYN--LDTFYTLTGKSGEIINKDKDNQLKLKLYGSK-IVQIIQGNIVASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDKIEPTLESNPQQTIMTMLQP--R

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

YGKFRSLLE----KTNVGQALEKGGIDEPYT
IFVPSNEALSNMTAGVLDYLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTLHIRSMANQ
IITFNISSKGQILANNVAVDETEVAAKNGRIYTLTGVLIPPSI--LPILPHRCNETKREM
KLGTCVRCFM-KNWSKCPTNSEPTAIFTNKCFYGSRAWNL---KIGCARYCDVTVEIPRC
CKGFFGPDCN-PCPGGFMNPCSGNGQCIDGLGGNGTCICEDGFQGSRCQFCSKP-NRYGP
QCNRTCQCVHGICDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPYM-QFCHIHATCEY
SNE---------------------------------------------------TASCVC
NDGYEGDGTL-CSKKDPCLGSTSRGGCSPNAECIQASTGTYSCVCQRGWTGNGRDCVEIN
SCLLPSSGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQIEKCHPL--
------------------ATCQYTLSGVWSCVCQEGYE-GNGVL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNVLMELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSMLSATSNLTVLVPSLQAIKDMDQNEKSFWLSRNNIPALIKYHTLLGT
YRVADLQTLPSSHMLATSLQGSFLRLDKADGNITIEGASFVDGDNAATNGVVHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPSLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLASAIEAADAYTVFVPNNEAIES
YIREKKATSLKEDILQYHVVLGEKLLRNDLHNGMHRETMLGFSYLLAFFLHNDQLYVNEA
PINYTNVATDKGVIHGLEKVLEIKKNRCDNNDTII-VRGKCGKCSQ--QTLCPLETKPLS
ET--RKCIYSVYFMGKRSIFIGCQLQCVRTIITSACCAGFFGPQCQACPGKGQ-NVCSGN
GFCLDGVNGTGTCECEQGFNGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGVKCDSEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTIPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRHAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAFCNHTEQDQRTCTCKPDYTGDGI
V

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIHSELPKNPSTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVQELAGPGPFTVFVPSSDSFNSESKLKV--WDK
QGLMSQILRYHVVACQQLLLENLKVITSATTLQGEPISISVS-QDTVLINKKAKVLSSDI
ISTNGVIHVIDTLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLITPKGASGRVLLNLTTVAANHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSKLIQD--SGLL
KVITDPMHTPVTLFWPTDKALQALPQEQQDFLFNEDN--KDKLKAYLKFHVIRDTMALAS
DLPRSASWKTLQGSELSVRCGTGS-DVGELFLNGQMCRIIQRRLLFDGGVAYGIDCLLMD
PTEGGRCDTFTTFNIPGECGSCFSTPR-CPLQSKPKGVRKKCIYNPL-PFRRDVEGCQNL
CTLVVHV-PRCCSGYFMPDCQACPGGPDTPCNNRGMCYDQYKPTGQCQCHTGFNGTACEL
CLPGRFGPD-CQPCGCSEHGQCDEGITGSGQCLCEAGWTGRFCDA---------------
-----------------PTVVIPVCIPACSMHATCMENNTCVCNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYKGDGHSCTEIDPCANGVNGGCHEHATCRMTGP
GKQKCECKSHYVGDGRDCEPEQLPLDRCLQDNGQCH-PDA-NCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACAKEAASIATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTIYASK
KCA-NIVGIVDYGTRTNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKAGYVGDGFSCNGNLLQVLMSF
PSLTNFL--------TEVLVFSRSSAQGRAF-LKHLTDLSIS

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLPKNKSLS
GRDIEHHLTNVNVSFYDDLVNGTV----LKTRLGSQLLITSSQDQLHQ-------EARFV
DGRAILQWDIIASNGVLHIISEPLKAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSY
FRLNQR-TTGFRRFESED-DIDALAFGKQQPESITN-PLYETST-PAAP----EPSCDPF
TDSGER---ELENS--DPLGALRS---

--------IMLQ-H-FIVFFLGLLVQNFCSPAETTGQ-AKRCDKKSLLTIRTQCRSCSLN
FEVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKEYLQPQCCPGHWGPD
CM-----------------ECPGGAGSPCNGRGNCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGSSCSAVCNCVHGVCNSGVDGDGTCECYSAYTGPSCDKPVP----ECAALLCPE
NSRCSPSSEDETKLECKCLPNYQGDGKYCEPINPCLQQ

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

VCHPHAHCTYLGPNRHSCTCQE
GYRGDGQVCLPVDPCQTNFGNCPAKSTMCKYDGPGQSHCECKDH--YSNFVPGVGCSLTN
ICESNNPCHRNANCTTIAPGQTECTCQKGYVGDGSTCYGNIMERLRELNTEPRGQWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVNELLMDNKAAQYFVKLHIIAGQ
MSTERMNH--TDTFYTLTGKSGEIFNSDKDNQLKLKLHGGSTRVKIIQGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKTAPTFESSTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYNKFRSLLE----ETNVGPALDEDGVGGPYT
IFVPSNEALNNM-DGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LVRFNTTDNGQLLANGVAMEEIDVAAKNGRIYTLAGVLIPPSI--VPILPHRCDETKREM
KLQTAPHL----------------SQFREREFYHGR--------NFCSERCCPRILIPKC
CKGFYGPDCS-QCPGGFLNPCSGNGQCADSLGGNGTCVCKDGFQGSQCQFCSDP-DKYGP
RCDKKCLCVHGTCDNRIDSDGACLPGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMGPCTGST-PGGCSRNAECIKTGVGTHTCVCQQGWTGNGRDCVEIN
NCLLP

PF12947 // ENSGT00760000119025_0_Domain_9 (1026, 1062)

GTGGCHDNATCLYVGPG---QNECECKKGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPVIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ASCQFS-SGVWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGNAAVELSFLAEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFNQWINNASLQPTLSVASNLTVLVPSQQATEDMEQDEKTFWLSQSNIPALIKYHTLLGA
YKVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHVINKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PRRGLTGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIEN
YIREKKVATLEEDILRYHVVLREKLLKNDLHNGMHRETMLGFSHRLGFFLRNEQLYVNEA
PVNYTNIATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGKCGKCPQ--QPICPFGTKPLG
DE-TRKCIYTFYFMGKRSVAIGCQPKCVRTVITRECCAGFFGPQCQPCPGKAQ-NACFGN
GICLDGINGTGVCECGAGFSGTACETCTEGKYGIHCDQ--VCPCVHGRCNQGPSGDGSCE
CDVGWRGVKCDSAITKDNCNGTCHTSANCLLNPDGTASCKCAAGFQGNGTVCT----AID
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEVSNGGCSAKADCKRTTPGRRTCVCRAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDRNAECTQT
GPNQAVCNCLPTYTGDGRV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTPISV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQ-ERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1767)

CRGSIYQELPKDPKTSQYFFQLQEH

PF02469 // ENSGT00760000119025_0_Domain_17 (1767, 1876)

SVKDLSGPGPFTVFAPLSAAFDEELRIKD--WDR
QGLIPQVLRYHVIACQQLLLENLKTTPNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKNLLITPKDTSGRILQNLTTLAINHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSNLIQD--SGLL
SMITDPIHTPVTVFWPTDQALQALPSEQQDFLFNQDN--KDKLREYLKFHVIRDTKVLAV
DLPRH-PWRTLQGSELSVTCGAGG-DVGKLFLNGQTCTVVQRELLFDLGVAYGIDCLLID
PTLGGRCDIFTTFDVSGDCGSCINTPS-CPRWSKPKGAKQKCLYN-L-PFKRNLEGCRQQ
CSLVIQL-PKCCKGYFGRDCQACPGGPETPCNNRGVCLDHYSATGECKCNTGFNGTACEL
CWPGRFGPD-CQPCGCSDHGQCEDGITGSGQCLCETGWTGHFCDT---------------
-----------------QEVLPPVCTPPCSAHATCKENNTCECNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKAATCSQNDTKVSCSCQTGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCTCKSHYVGDGMD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPVDRCLQDNGQCHAD--ADCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACAKEAATIATYNQLSYAQKAKYHLCS-AGWLDGRRVAYPTAFASK
KCGLGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2553)

YRMK--DVNCTCKVGYVGDGFSCNGNLLQVLMSF
PSLTGLARLMTPLLSQDVLAYSNSSARGREF-

PF02469 // ENSGT00760000119025_0_Domain_27 (2553, 2664)

LEHLTDLSTRSTLFAPQNSGLGGNENLS
GRDIEHHLSNVNMVSYDDLVNGTT----LPTGLGSQLLITSSQDPLHV------KETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTSTHPGLVIGMVFASFLVTGAVALAARSY
FRLNRR-TIGFQHFESEE-DIDVATLGKQQPENISN-PMYESTT-SAPS----EPAYDPF
ADCDEQ---QLESS--DPLGAL-----

---------MDKRL-LILFLLGLVMSNLCLMAATIQQGTNRCDKKMLVTARTECRSCSLN
SQIKCPEGYIKVTNGSSGTRDCR-YPLEIRTYTLSLPGCRHICRKEYLQPQCCQGHWGPD
CM-----------------ECPGGAGSPCHQRGRCSDGI-QGDGSCTCLEGFGGTACETC
AEDHLFGPNCTSVCQCVHGVCNSGIKGDGACTCYSAYTGAYCDKPIP----ECESLQCPE
NSRCSTSNVDESKLECKCVPNYKRDGKHCQPINPCLQNVCHANADCSYLGPNRHKCSCQE
GYKGDGKVCLPVDPCQENFGNCPTKSTVCVFDGPGKSHCACKEH--YRNFVPGKGCSMTD
ICESRNPCHKNANCTTVSPGQTECTCQKGYVGDGSLCYGNIMERLKELNTEPRGLWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFISLLD-KAYAWPLSNLGPFTVLVPT-NKGLKGIDVKDLLTNKENAQYFVKLHIIAGQ
LNSGGLNN--TDTFYTLTGKSGEVFSRDKDNQFKLRLYGGRKKGKIVQGDIIASNGILHI
IDKA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

LDKMEPTFASNAEETIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYNKFRSLLE----KTNVGQALDDDGVGGPYT
IFVPSNEALDNMKDGVWDYLLSPEGSRKLLEMVRYHIVPFTQLEVANIISIPHIRSMANQ
MIQFNTTLSGQILVNGAATEEIEVVARNGRIYTLTGVLTPPSI--VPILPHRCDETQKEM
KTGTCLSCSL-VYWSICPADSEPTALFTHKCVYTSKMGTLRFPKSGCARYCNATIKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGVSGNGTCMCDDGFQGSFCQFCSDP-NKYGP
RCEKKCACVFGKCDNRIDSDGNCLAGSCQSGYAGKFCDKQTTSCGPFV-QFCHAHANCEY
SSG---------------------------------------------------AASCVC
KPGYQGDGII-CTEIDPCAGLI-PGGCSSNADCIKTGIGTHSCVCQPGWTGDGRDCSEIN
NCLLPNFGECHTNATCLYVGPG---QHECECKKGFRGNGIDCEPIKSCLEQEGKCHPL--
------------------ATCQSTSSGVWNCVCQDGYE-GDGFRCYGNAAEELSFLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

AFNQWVNEASVRPMLTATANLTVLVPSHHATENMAPDEKTFWMSKNNIPTLIKYHILVGT
YRVADLQILSSSDMLATSLRGNFLHLTKENGNITIEGASIVQGDHAATNGVIHIVSKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PLRSMSGSLPTLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

EYSIFRGYII----QYSLANAVEAAESYTVFAPNNDAIEN
YIREKRLSSLNEDILRYHIVLEEKLLKNDLHNGMHRETMLGFSYHVGFFLQNGQLYVNEA
PINYTNVATDKGVIHGLGRVMEIQKNRCDNNDTTI-IRVSCRARLP---AIENFSYFSQA
EE-MKKCISTNYFMGKRSMFLGCQPRCVKTVITRECCAGFFGQQCQPCPGKAG-NACFGN
GICLDGVNGTGVCECEEGFSGTACETCTDGKYGPSCDQ--VCACVHGKCSQGAEGDGTCE
CEVGWRGVKCESEIKEDECNGTCHTSANCLTNPDGPPSCKCAAGFQGNGTACA----AID
ACETRNGGCSAKADCRRTTPGNRVCVCKAGYAGDGIVCLEINPCLENNGGCDKNAECTQT
GPNQAVCNCLRAYSGDGKTCTLINICRTKNGGCSEFAICNHTGLDERTCTCKPDYIGDGF
NCRGTVYQELPKNPRTSTYFYQL

PF02469 // ENSGT00760000119025_0_Domain_17 (1764, 1876)

QENLVRDLASPGPFTIFVPSSEAFEESQQVKD--WTT
KGIMPQILRYHMVACNRLLFDDLKSTPNITSLQGEMLKITFS-QDTVYLNGKAKIISSDA
ISTNGVIHVIDKLLI

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNTQVILKDTSGNNRENLTTVATSNG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YSKFSKLLQD--AGLL
RLINDPIHEPVTLFWPTDEALGQMPMEQQDFLFGSDN--KDKLKEYLKFHIIRDAKILAV
DLPSVVSRKTLQGSEISVKCGDDN-NIGELFLNDRKCKIVQRQLEFDSGIAYGIDCMLMD
PSLGGRCDNFITFKVSGECGSCYNTPG-CPVWSKPKGVRQKCSYN-L-LFRRNLDGCRQV
CTMVMRV-PKCCKGYFGRDCQACPGGPENPCNNRGICTDEYFGAGECRCNTGFNGTACEL
CLPGRYGTD-CKPCECSGHGQCDDGASGSGRCFCETGWTGRFCDT---------------
-----------------KLALPPKCSPPCSNHAVCKENNTCECNLNYEGDGITCTVVNFC
AQNNGGCSKVSKCSQKGTKVTCTCQKGYRGDGHTCIPVDPCADGFNGGCHEHAICTMTGP
GKNKCECKSNYVGDGLDCAVMQFPIDRCLQGNGQCHAD--ANCADLHFQDSSV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PQGQYKLTYDKAKEACANEEATVATYNQLSYAQKANYHFCA-AGWLDNGRVGYPTAYSNP
NCGSGFVGIVDYGPRVNRSEMWDVFCYRVK--DVNCTCKPGYVGDGFACSGNLLQVLMTF
PMFTNFL--------MDVLEYSNSSAKGKEF-LKHLTDLSSQGTFFVPNNDGLKENETLS
GRDIEYHLSNVSTLFYDDLVNGTT----LQTRIGSQLLITFGQDPPNT------NETRFV
DGKAILQWDIYASNGIIHVISEPLRAPPAPAASVHAGVGAGIFFTITLILGGIAFAGYSY
LRFSRR-TTGFQHFESEE-DITVSTLD--KPSNISN-PMYESST-SSPL----EATEDPF
CESDEQ---QLVTS--GAHGEL-----

--------IMRKSL-KPSFLLGFIIHILCSLAGALEQ-AKRCDKKTLITTRTECQSCSLN
RRINCPEGYTKVTNGSSGVRDCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-X-----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEGFGGTACETC
AEENLXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXIPECDALLCPE
NSRCSPSSIDESILECKCLPNYQGDGRHCEPINPCLQKVCDDNAHCTYLGPNRHRCTCRD
GYKGDGQVCVPVDPCQEDFGGCPAQSTVCQYDSPGKXXXXXXXX--XXXXXXXXXXXXXX
XXXXXNPCHKNANCTMRAPGQTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_4 (418, 548)

XXX
XXXXXXXX-KAYAWPLSNLGPFTVLVPT-NKGLKGTNVKELLMDKNNAQYFVKLHIIAGQ
VDTEALNS--TDTFYTLTGKSGEILSGDKDDQLRLKLSGGKKKGKIVRGDIIASNGLLHI
IDKAMD-

ENSGT00760000119025_0_Linker_4_5 (548, 569)

MAPLFEASTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSRFRSLLE----VTNVGQALGEDGVGGPYT
IFVPSDEALNNMKDGILDYLLSAEGSRKLLELVRYHIVPFTQLEVANIISKPHIRTMANQ
IIQFNTTSNGQILANEVAVEEMEVVAKNGRIYTLAGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--IPILPHRCDETHRDM
KLGTCVSCGM-VYWSVCPANSEPLXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXIPKC
CKGFYGPDCN-Q

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSNPCSGNGQCADGLSGNGTCICDDGFQGSRCQFCSDP-GKYGP
QCEKKCLCVHGKCDNRIDSDGSCLPGTCKDGSAGKFCDKQTTACGPYV-QFCHIHANCEY
SSR---------------------------------------------------VASCVC
KQGYEGDGTI-CTEVDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CAGII-PGGCSSNAECVKTGTGTHMCVCQPGWTGDGRDCTAIN
NCLLPNFGGCHDNATCLYVGPG---QXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
------------------ANCQSTSSGLWSCVCQDGYE-GDGLMCYGNVAVXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF02469 // ENSGT00760000119025_0_Domain_11 (1194, 1261)

YHALVGT
YRTSDLQILSSSDMLATSLQGNFLHLAKVNGNITIEGANIVDSDNAATNGVIHVIDKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSMSTSLPNLLSRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QYNLATAIEAADTYTVFAPNNEAIEN
YIRKKD-WSLEESILRYHIILEEKLLKNDLHSGMHRETMLGFSYLVGFFLQNGQLYVNEA
PVNYTNVATDKGVIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1488)

IQKNRCDSNYTTI-VRXXXXXXXXXXXXXXXXXXXXXX
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKECCAGFFGPQCQL

PF07974 // ENSGT00760000119025_0_Domain_13 (1488, 1524)

CPGKAR-NACFGN
GICLDGVNGTGVCECEGGFNGTACETCMEGKYGSSCDQ--XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXCLLKSDGTAYCKCAAGFQGNGTVCT----AID
ACEISNGGCSTKADCKRTTPGKRVCVCRAGYTGDGIICLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDQNAECTQI
GPNKAACNCLRGYAGDGKT

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CT-INI

PF00008 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTRNGGCSEFAVCNQTAVEERTCTCKPGYKGDGF
I

ENSGT00760000119025_0_Linker_16_17 (1742, 1755)

CRGPIYLELPKNT

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

ATTPYFFHLQENTIRDLMGPGPFTVFVPSKEALENASQVKA--WTT
QGVMPQMLRYHMVSCHQLLLENLKLIPSMTSLQGEAVHITVS-QDTVYLNGKAKIISSDI
ICNNGVIHIIDQVLV

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PKNLQEIHKDASGNNMENLTSVAIRQG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YLKFSSMLQD--AGLL
SVINDPIHKPVTLFWPTDKALEALSQEQQNFLFD-----KDKLKDYLKFHIIRDSKILAV
DLPSVASRKTLQGSELNVKCGDEN-NIGDLFLNDQKCRIVQRQLEFESGVAYGIDCMLMN
PSLGGRCDNFIIFNVSGSCGSCYNVPR-CPTWSKPKGVKQKCFYDL--PFRRHVEGCQQK
CTMVMRL-PKCCKGYFGRDCQACPGGPTTPCNNRGVCIDEYSGGGECRCNTGFNGTACEL
CWPGRYGPD-CKXXXXXXXXXXXXXXXXXXX-----------------------------
---XXXXXXXXXXXXXXXXXLPPVCSPSCSKYATCKENGTCECNLHYEGDGITCTVVDY

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCSKVAKCSQVGTVVTCSCQKGYKGDGHI

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CIAVDP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGLNGGCHEHAVCIMTGP
GKHRCECKSHYVGDGLDCVVEQLPVDRCLQNNGQCHAD--ANCADLHFQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00193 // ENSGT00760000119025_0_Domain_26 (2432, 2487)

XXXAKYHLCS-AGWLNDGRVAYPTAYSSQ
NCGSGFVGIVDYGSRPNKSERWDVFCYRIK--DVNCTCKVGYMGDGFACNGNLLQVLMSF
PSLANFL--------SEVLIYSNSSSRGKAF-LKHLTDLSTHGTLFVPNNDGFWENKXXX
XXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXX-----XNETRFV
DGQAILQWDIFASNGIIHIISGPLKAPPAPTXXXXXXLGAEVL---TIIVGAIALAGY-Y
FRINRR-TIGFQ-FEPEE-DIDVTALGKQPSSNISN-PMYDSTT-TQPP----EPTYDPF
S--------------------------

QRRSQNVLAMLQ-N-LMLFFLGLVAQNLCSLPETTEQ-AKRCDKKAVLIMRTECQPCSLN
FGTKCPDGYTKITNGTVGVRDCR-YPFEVRTYTLSLPGCRHICRKDYLQPQCCPGHWGPD
CM-----------------ECPGGAHSPCSGRGSCAEGM-EGNGSCSCQEGFGGTACENC
ADDNVFGPSCSAACPCVHGVCNSGIHGDGTCECFSGYTGPNCDKPIP----ACAALFCPE
NSRCSPSSKDETTLECKCLPNYKSDGKSCEPINPCSQNICHPHAWCTYLGPNRHSCTCQE
GYRGDGQVCFPVDPCQVNFGNCPTDSSVCRYDGPGQSHCECREH--YHNFVPGVGCSMTD
ICESHNPCHRDARCTTIAPGQTKCTCRKGYIGDGSRCYGNIMERLRELNTEPGGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTLLLPT-DKGLKGFNVKELLKDNEAARYFVKLHIIAGQ
MNTEQMTTLQMKTFYTLTGKPGEIFNGDKDNQVKLKLYGGKKKVNIIQGNIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKVAPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNMGHALDEDGVGGPYT
IFVPSNEALNNMKDGALDYLLSSEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
VIRFNTTDNGQILANGVAMEETEVAAKNGRIYTLTGVLIPPSI--TPVLPHRCDEMKREM
KLVRKLPCVS-S-------LAFFQTLFTHKCVYTGRIRSL---KNGCARYCNATVKIPKC
CEGFYGPDCI-QCPGGFLNPCSGNGQCADGLDGNGTCICQDGFRGSQCQFCADP-NKYGP
QCDKRCLCIFGTCDNRIDSDGACLPGTCREGSAGRFCHKHTSACGPYM-EFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGSL-CSETDPCSGLT-PGGCSRNAECIKTGRGTHTCVCHQGWTGDGRDCSAIN
TCLLPRAGGCHHNATCLYVGPG---QNECECKKGFRGNGIDCELITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGRCHPL--
------------------ATCQFT-SGVWSCVCPEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGN---ELSFLSAAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

VFNQWINSASLQPLLSATSNLTVLVPSRQAIEDLDQEEKAFWLTKSNIPALIKYHTLLGT
YGVADLQALSPSDMLATSLQGSFLHLAKVNGNITIEGASVIDGDNAATNGVIHIINKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLASTIEAADAYTVFAPNNDAIES
YIREKKVTTLEEDVLRYHVVLEEKLLKNDLHTGMHRETMLGFSYLLGFFLHNDQLYVNEA
PINYTNAATDKGVIHGLGKVLEIQKNRCDVNDTTI-VRGKCGKCPQ--QPICPFGTKPLG
DE-TRRCLYTIYFMGKRSLFIGCQPKCVKTVITKECCAGYFGPQCQPCPGSAE-GICFGN
GICLDGANGTGVCECGGGFGGTACETCVEGKYGAHCDQ--VCTCVHGRCNQGPSGDGSCD
CDVGWRGVKCDSEITKDNCNGTCHTSANCLLNPDGTASCRCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSTKAICKRTTPGSRECVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCHRHAECTQT
GPNQAVCNCLAKYTGDGKVCTLIDVCLTENGGCSKFAFCNHNEQDGRTCTCKPDYIGDGF
TCRGNIHQELPKNPQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1756, 1876)

TSQYYFQLQEHSIHDLLGPGPFTVLAPSSAAFDAEPQIKN--WDK
QGLMPQVLRYHVIACHQLLLENLKSTPNATSLQGESLTISVS-QGTVFINNKAKIISSDI
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PQNLLITPQDASGRILQNLTTVAVNHG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

FKFSNLLQE--MGLL
SVITDPIHTPVTLFWPSDQALQSLPPEQQGFLFNQDN--KDKLKEYLKFHVIRD--VLAV
DLPRFATWKTLQGSELSVKCGAGS-DIGELFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFNVSGNCGSCISTPS-CPRWTKPKVRMRKCLYN-L-PFKRNVEGCKQQ
CTLVIQL-PRCCRGYFWPDCQACPGGPDTPCNNRGVCLDQYSPMGQCKCNAGFTGTACEL
CGQGDLGLIVSVPCGCSDHGQCDDGITGSGQCVCETGWTGRFCDT---------------
-----------------QTAVPPVCTPPCSAHATCTENSTCECNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVATCSQKGTKVSCSCQKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GKRKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--ADCADLHFQDTTIG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACAKEAATVATYNQLAYAQKAKYHLCS-AGWLDGGRVGYPTSYASQ
NCGSGVVGIVDYGPRNNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2561)

YRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSL
PSLTDFL--------GEVLAYSNSSARGRAF-LKHLTDLS

PF02469 // ENSGT00760000119025_0_Domain_27 (2561, 2664)

LRSTLFVPQNSGLGENETLS
GRDIEHHLSNVSIFFYDDLVNGTI----LHTRLGSQLLITSSQDQHQ-------LETRFV
DGRAILQWDIFASNGVIHVISRPLKAPPTPVTLSHSGLGTGMFFAVILVIGAIASAAYSY
FRLNKR-RVGFQHFESEE-DIDVAALGKQQPDNISN-PMYESTT-AAAL----GPSHDPF
VDAETQ---QLASS--DPLGAL-----

---------MLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LRVKCPDGYTKITNGSVGVRDCR-YTFEVGTYSLSLPGCRHICRKDYLQPQCCPGHWGPG
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEVFGGTACETC
ADDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYHGDGQVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKEH--YHNFVPGMGCSMTN
LCKTNNLCHRNANCTTVAPGRTRCICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEHMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKKKVKIIEGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELIRYHIVPFTQLEVATLVSTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCLGNGQCADSLAGNGTCICEEGFQGSQCQFCSDP-NKYGP
QCNKKCLCVHGTCDNRIDSDGACLTGTCRGGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPGLIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLGFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-LRGKCRTCSS--ELICPFGTKPLG
NE-KRRCIYTTYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCQPCPRNAQ-NVCFGN
GICLDGVNGPGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGTCHTSANCLPNSNGTASCKCAAGFQGNGTTCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKANCKRTTPGRRVCMCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINI

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPMVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLIN
PTLGGRCDTFTTFDASGECGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLTNVSMFFYNDLVNGTT----LQTRLGRKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMTLTHTGLGAGIFFAIILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

-RRSKYFLIMLQ-H-LVIFCLGLVVQNFCSPAETGQI-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGHWGPD
CI-----------------ECPGGAESPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPSCSAVCNCVHGVCNSGLDGNGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQKICHPRAHCTYLGPNRHSCTCQE
GYRGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
ICKTNNLCHRNANCTTVAPGQTQCICRKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DKGLKEFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKTKVKIIQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGRVLDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 798)

PPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGF

PF00008 // ENSGT00760000119025_0_Domain_6 (798, 827)

SNPCSGNGQCADSLAGNGTCICKEGFQGSRCQFCSDP-NKYGP
QCNKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKRTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTSCLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQERYE-GDGFLCYGNVAVELSFLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFNQWINNASLRPVLSAALNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKMDGNITIEGASIVDGDNAATNGVIHVINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNNAIKN
YIREKKVLSLEKDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYVLGFFRHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-VQGRCRTCSS--ELICPFGTKPLS
NE-KRRCIYTSYFMGRRTLFIGCQLRCVRTVITRECCAGFFGPQCQPCPGNAQNNACFGN
GICLDGVNGIGVCECEEGFSGTACETCPEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVRCENVTTEDNCNGTCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
ACKISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKVCTLINICLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
TCRGNIYQELPKNPKTSQYFFQLQE

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLISISNATSLQGEPIVISIS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGSCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSGTGMCKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCMPPCSPHATCKDNNTCECNLDYEGDGITCTVVDFC
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLSCTEIDPCADGLNGGCHEHATCKMTGP
GKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHAD--ANCVDLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAKEACANEAATVATYNQLSYAQKANYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIHGTLFVPQNSGLGENETLS
GRDIEHHLANVSVFFYNDLVNGTT----LKTRLGSKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMGLTHTGLGAGIFFAVILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAAGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

--------IMLQ-H-LVIFCLGLVVQNFCSPAETTRQ-ARRCDRKSLLTIRTECRSCTLN
LRVECPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPQCCPGHWGPY
CI-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQKV

PF12947 // ENSGT00760000119025_0_Domain_2 (280, 309)

CHPHAHCTYLGPNRHSCTCQE
GYHGDGQVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKEH--YHNFIPGMGCSMTN
LCKTNNLCHKNANCTNVAPGQTRCICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEHMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKKKVKIIEGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKLEPTFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGRALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYW-RCPANSEPTALFTHSCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLAGNGTCICEEGFQGSQCQFCSDP-NKYGP
QCNKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDRQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT

PF00008 // ENSGT00760000119025_0_Domain_8 (983, 1012)

-PGGCSHNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPDAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANAIEAADAYTVFAPNNNAIEN
YIREKKVLSLEKDILRYHVVLEEKLLKNDLHNGMHRETMLGFSYSLGFFLHNDQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNNTTI-LRGKCRTCSS--ELICPFGTKPLS
NE-KRRCIYTTYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCQPCPRNVQ-NVCFGN
GICLDGVNGPGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGTCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCMCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINI

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGSIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPMVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--LGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFDALGECGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCRER
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM
CWPGRFGPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMVFYNDLVNGTT----LQTRLGSKLLITASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMTLTHTGLGAGIFFAIILVIGVVALASYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGIH-----

---------MLQ-C-LVFMFLGLVLQKSCSLTEATEQ-GKRCDKKSVLTIMTKCEPCWLH
SKTTCPDGYKKIINGSVGIRDCR-YTFKVDTYSLALSGCRHICRKNYLQPQCCPGYWGPD
CM-----------------ECPGGAESPCSGRGSCAEGM-DGSGNCFCQEGFGGTACETC
AYDYLFGPNCSSVCKCVHGVCNSGLQGDGSCECYSAYTGPSCDTPVP----ECEALLCPE
NSRCSPVSKDETKLECRCLPNYEGDGRNCEPINPCLQRPCHPSARCTYLGPNQYNCTCGK
GHVGDGRVCLPVDPCQTDFGNCPPQSTVCKYDWPGQSHCECKEH--YHNFVPGFGCSMTN
ICKSKNPCHRNANCTMIAPGQTKCTCQNGYVGDGFKCYGNIMERLQELNTVPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFISLLD-KVYAWQLSTLGPFTLLLPS-ESEPTAFNVEELLKDPTAARNFVQLHIIAGP
MDTEQMNS--TDTFYTLTGAPGRIFNRDKDNQIKLELHKGKKKVKIVEGNIIASNGLIHI
LDTA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIQPTFESNSKQTIMAMIPS--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYRHFRTFLE----KTNLKSALDGQGPGGPYT
VFVPSDEALNNLKDGALHYLLSPEGSPKLLELVRYHIVPSTQLEVAILITKLETRTMANQ
IIQFNVTDNGRILANNVTIEDIEVTAKNGQIYTLAGVLIPPSI--VPILPHRCDEMKSEM
RLGSCVNCML-KSQSKCPADTEPTEIFTDKCIYSSRTGNT---KNGCARHCNATVRITKC
CKGFFGPYCN-QCPGGFRNPCSGNGQCADGVHGNGTCTCKDGFSGSRCQFCSDP-NKYGP
QCDKKCPCLLGTCDNRVDSNGACLAGTCQGSAWGKFCNRKFQDCGLLA-HFCHVHATCEL
EPHTIRLRRARDNVSTVYRPIAERLKELRLPSVNQTEKFVIRTGPHHSKSLSLPFSFCVC
KDGYEGNGLE-CFEKNPCAEPD-RGGCSQNAECIKTGPGTHTCVCQPGWTGSGRDCAEIN
PCLQPSQGGCHRDATCLYVGPG---QNECECQKGFRGNGIDCEPTIACLDEFDKCHPL--
------------------ATCQAVASGVWDCVCLYGYK-GDGILCYGSAAIELLFLFEAV

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

TFTSWVHKASLQTMLSTSSNFTILVPSQQAVEDMDQDAKNFWLSRSTIPVLIKYHILLGT
YSVTDLHSLPSSHMLATSLQGSFLCLQKADGNVTIGGATIIDGDIAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PPRSQSGILPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANVIEAADAYTVFAPNNAAIEN
YTREKKVTTLEEDTLRYHVVLKEKLLKNDLRNGMHRETMLGPSYLLGFFLRNDQLYVNEA
PINYTNVATDKGVIHGLETVLEIQKNRCDNKKTNV-VRGTCGKCPQ--PPICPPGTKLLG
NE-TSKCIFSFYFMGRRSVLIGCRPMCVRVLITRACCAGFFGPQCQACPGQRG-GACFGN
GICMDGVNGTGTCKCSPGFNGTACETCADGKYGVHCDQ--ECSCVHGRCNQGPSGDGSCD
CYVGWRGVRCDSAITEDRCNGTCHTSANCLLSPDGKTLCRCAAGFQGNGTVCK----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETRHGGCSPKADCKRTSPGNRVCVCKAGYTGDGIVCLEINPCLENHGGCDGNAECTHT
GPNQAVCNCLPTYTGDGKACTLLSV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSPNAICNQTGTGERTCTCKQNYTGDGL
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1768)

CRGSIYEELPKDPQTSQYFFQLQEHE

PF02469 // ENSGT00760000119025_0_Domain_17 (1768, 1876)

VRELARPGPFTVFVPASAAFNVEPQIKD--WDR
QGLMPQVLRYHVVACHQLLLENMKLTPNVTSLQGEPIVISVS-QDTVYINNKAKIISSNI
ISTNGVVHVIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLLVTPRDASGRILQNLTTVATNNG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2038)

YRRFSKLLQD--SGLL
SVITNPIHTPVTVFWPTDQALQALPQEQQNLLFNQ-N--KDKLNEYLKFHVIRDSKVLAA
DLPRSASWKTLQGAGLSVQCGAGS-DIGELFLNNQMCRIVQRELLFDLGVAYGIDCLLRD
PTVGGRCNNFAVYSTTGNCGSCLSTPR-CPRGTKPQGMKIKCLWAML-PFRPPVEGCKNK
CALAVQL-HMCCKGYFLPDCQACPGGPDTPCNNRGTCLEWYSAKGQCRCDTGFNGTACEL
CGPGRFGPD-CQPCGCSEHGQCDEGILGSGQCLCDSGWTGRLCNT---------------
-----------------RAAVSPVCTPPCSAHATCVENNTCECNLNYEGDGITCTVVNF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCANIAQCSQKGTKVSCSCPKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CMEIDPCTDGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCTMTGP
GKHRCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPERLPLDRCLQDNGHCHAD--ADCTDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHIRS
PVGQYKLTFDKARVACANEAATLATYNQLSYAQKAGYHLCS-AGWLDSGRVAYPTAYASQ
NCGRNVVGIVDYGLRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2584)

YRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSL
PLLKNFL--------TEVLAYSNRSARGRAF-LRHLTDLSIHSTLFVPLNSELGGNETLS
GRD

PF02469 // ENSGT00760000119025_0_Domain_27 (2584, 2664)

IEYHLITVSTVFYDDLVNGTT----LQTRLGSQLLITSDRDQISL------NETRFV
DGRAIVLWDIFASNGIIHIISRPLKAPPAPATSTHAGLGTGIFFGIILVAAAIALAVYSY
FRLTHR-AIGFQRFESEE-DINFAALGKQRPENISN-PMYNSRSV-APP----PAPCDPL
GPLEEL-----DSS--DLLGTGAL---

---------MLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LGVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGHWGPD
CI-----------------ECPGGARSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----QCAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPRAHCTYLGPNRHSCTCQE
GYRGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
ICKTNNLCHRNANCTTVGPGQTQCMCRKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DEGLKEFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--TDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKNKVKIIQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLAGNGTCICKEGFQGSQCQFCSDP-NKYGP
QCNQKCPCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SSG---------------------------------------------------TASCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATKDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIAN
YIREKKVPSLKEDVLRYHVVLEEKLLKNDLHNGMHRKTMLGFSYFLGFFRHNNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTRPLS
NE-KRRCIYTSYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCLPCPGNAQ-NVCFGN
GICLDGVNGTGVCECEEGFSGTACETCTEGKYGTHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDNCNGMCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYMGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGNIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVGPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLILISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGSCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKKNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYTGTGMCKCNTGFNGTACEM
CWPGRFGPN-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQTGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANETATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCSCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLVTASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMSLTHTGLGAGIFFAVILVIGAVALAAYSF
FRLNRR-TIGFQHFESEE-DINVAAVGKQQPENISN-PLYESAT-SAPP----EPSYDPF
TVSLHS---YLG-I--GSLGVQGNDVF

--------------------------------------TKRCDKKSLLIMRTECQSCSLN
FGIKCPDGYTKVTNGSMGVRDCR-YTFEVRTYSLSLPGCRHICRKTYLQPQCCPGHWGPD
CM-----------------ECPGGASSPCSGRGSCAEGM-GGNGSCSCQKGFGGTACETC
ADDNLFGPNCSAVCSCVHGVCIS

PF04863 // ENSGT00760000119025_0_Domain_1 (204, 233)

GIAGNGTCECHSAYTGPNCDKPIP----E

ENSGT00760000119025_0_Linker_1_2 (233, 275)

CADLLCPQ
NSRCSPSSEDETKLECKCLPSYKGNGQFCEPINP

PF00008 // ENSGT00760000119025_0_Domain_2 (275, 309)

CLQNICHPHARCTYLGPNRHSCTCQE
GYHGDGRVCLPVDPCQTNFGNCPTKSTVCIYDGPGQSHCECKKH--YHNFEPGVGCSVTD
ICASHNPCHRNANCTTIAPGQTKCTCQKGYVGDGSMCYGNIMERLRELNTKPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGLNVKELLMDNEATQYFVKLHIIAGQ
MNTKQMNN--TDTFYTLSGRSGEIFNDDKDNQLTLKLYGGKKNVKIIQGNITASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KMAPTFESNSEKTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDKDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSWKLLELIRYHIVPFTQLEVASLISTPHIRSMANQ
IIQFKTTENGQILANDVAMEEVEVTAKNGRIYTLTGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--VPILPHRCDETKREI
KLGTCVSCSL-VHWSKCA-NSEPTALFTHRCVYTGKTRSL---KSGCAKYCNATVKVPKC
CKGFYGSDCN-Q

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSNPCSGNGQCADGLGGNGTCICQDGFQGSQCQFCSDP-NKYGP
RCDKKCLCIYGTCDNRIDSDGACLAGTCRDGSTGRFCHKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGSL-CSESDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CSGLT-LGGCSRNAECIKTGTGTHSCVCQQGWTGNGRD

ENSGT00760000119025_0_Linker_8_9 (1016, 1022)

CSEIN
N

PF00008 // ENSGT00760000119025_0_Domain_9 (1022, 1062)

CLLPGAGSCHDNATCLYVGPG---QNECECKEGFRGNGIDCEPITSCLEQTEKCHPL--
------------------ATCQFT-SGIWSCVCQEGYE-GDGFLCYGNAAVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

AAA
LFNQWIHNASLQPILSAASNLTVLVPSQQAIEDMDQDEKAFWLSKSNIPTLIKYHTLRGT
YGVADLQTLSSSDMLATSLQGNFLRLAKKDGNITIEGASIVDGDNAATNGVIHIINKVLF

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QFNLANAIEAADAYTVFAPNNDAIEN
YIREKKVTTLEEDILRYHVVLEEKLLKNDLHNGMHRETMLGVSYLLSFFLHSDQLYVNEA
PINYTNVATDKGVIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1488)

IQKNRCDNSNTTI-VRGKCGKCPQ--QPICPFGSKPLG
EE-TMKCIYTIYFMGKRSVFIGCRVKCVKTVITRECCAGFFGPQCQL

PF00008 // ENSGT00760000119025_0_Domain_13 (1488, 1524)

CPGKAQ-NVCFGN
GICLDGVNGTGVCECGEGFSGTA

ENSGT00760000119025_0_Linker_13_14 (1524, 1622)

CETCVEGKYGIHCDQ--ECSCVHGRCNQGPSGDGSCE
CDVGWRGVKCDREITKDNCNGTCHTSANCLLNPDGTALCKCAVGFQGNGTICT----AIN
P

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTMPGSRTCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CIEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAVCNCLPKYTGDGKDCSLINTCLTKNGGCSEFAICNHTGQEERTCTCKPNYIGDGF
TCRGNIHQELPKNP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQYFFQLLEHSVRDLVGSGPFTVFAPLSAAFDEEPRIKD--WDK
QGLMPQVLRYHVIACHQLLLENLKSTPNATSLQGESIVISVS-QDTVYINNKAKIISSDI
ISTNGIIHIIDKVLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNMLITPQDASGRILQNLTTVAINHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2009)

-YIKFNNLIQG--AGLL
SIISDPIHTPVTLFWPTDQALQALPAEQRDFLFNQDN--KDKLKEYLKFHVIRDAKVSAA
DLPRSTAWKTLQGSELSVKCGAGS-DIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXGDCGSCVYTPS-CPRWTKPKGVKQKCLYN-L-PFKRNLEGCRQQ
CALVIQL-SRCCKGYFGRDCQACPGGPDTPCNNRXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXCGCSDHGQCDEGITGSGQCLCEAGWTGRFCDT---------------
-----------------RAVLPPVCTPPCSAHATCKENNTCECNLNYEGDGLTCTVVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTKVSCSCSKGYQGDGHSCTEIDPCADGLNGGCHEHATCKMTGP
GKKKCECKSHYVGDGLDCEPEQLPIDRCLQDNGQCHAD--ASCADLHFQDST

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

VGVFHLRS
PLGQYKLTFDKAKEACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAYASQ
NCGSGVVGIVDYGPRNNKSEMWDVFCYRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------MGVLAYSNSSARGRAF-LKHLTDLSIRSTLFVPQNSGLGENETLS
GRDIEHHFANVSIFFYNDLVNGTI----LQTRLGSQLLITSSQDQGQ-------LETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTAVHTGLGTGIFFAITLVIGAIALAAYSY
FRLHRR-TTGFQRFESEE-DIDVTALGKRQPENVSN-PMYESAT-SAPP----EPSYDPF
TVSEEQ---QLESG--DPLGVQ-----

---------MLQ-H-FTLVFLGLVVQNFCSLAETTGQ-AKRCDKKSLLTIRTECQSCRLN
AGVKCPDGYRKITNDSEGVRDCR-YTFKVRTYSLSLPGCRHICQKDYLQPQCCPGHWGPD
CM-----------------ECPGGAGSPCSGRGTCAEGM-EGNGSCSCQEGFGGTACETC
ADDNLFGPSCSQVCNCVHGVCNSGLNGDGTCECFSAYTGPSCDKPVP----ECAALLCPE
NSRCSPSSEDETKLECKCLPDYKGDGKECEPINPCLQNVCHPHAHCTYLGPNRHSCTCKE
FYHGDGHVCLPTDPCQTNLGNCPTKSTVCKYDGPGQSHCECKEH--YNNFVPGVGCSMTN
ICESNNPCHKNANCITIAPGQTECTCQKGYVGDGSVCYGNIMERLRELNTEPRGKWQGKL
ISFISLLE-RIHAAPLPCPNPRSWDVPR-ASCLWMLHIK

PF02469 // ENSGT00760000119025_0_Domain_4 (460, 545)

ELLMDKEAAEYFVKLHVIAGQ
LSTERLTT--MDTFYTLTGKSGEIFS-DKDNDLKLKLHEATNTVKIIEGNIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 568)

MDKIAPTFESNTELTIMQMLQP-

PF02469 // ENSGT00760000119025_0_Domain_5 (568, 700)

-RFSKFRSLLE----ETSVGRTLDEDGFGKPYT
IFVPSNEALENMKDGTLDYLRSPEGSRKLLELVRYHIVPFTQLKVAALIATPQIRSMANQ
IIQFHTAVNGQILANDVAIEETEVAAKNGWIYTLTGVLIPPSI--TPILPHRCDEIKREI
KLGTCASCYL-IYQSKCPANSVPTSLFTHKCVYSSRRRSL---KSGCARFCNATVKVPKC
CKGFYGPDCS-QCPGGFSNPCSGNGQCADGLDGNGTCICEDGFQGSRCQFCSDP-QKYGP
RCDQKCLCAHGTCDNRIDSDGSCLSGTCRDGSTGKFCDKQPSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TAGCVC
KAGYEGDGIL-CSEMDPCMGLT-PGGCSPNAECIKTGTGTHACVCQQGWTGNGRDCWEIN
NCLLPGAGGCHDNATCLYVGPG---QNECECKSGFRGSGIDCEPIVSCLEQASICHPL--
------------------ATCQLAAAGVWSCVCREGYGIGTVLMCIIFMNKELSFLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

VFNQWIHNASLQPMLSTTWNLTVLVPSQQAIEDMDQDEKSFWLSQSNIPALIKYHTLLGT
YGVADLQTVSASDVLPTSLQGHFLHLEKVDGNVTIEGASIVDGDNVATNGMIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRVLTGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLVNAIEAADAYTVFAPNNDAIEN
YVREKKVTTLEEDIVQYHVVLDEKLLKNDLHHGMHRETMLGFSYLLGFFLRNNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTSI-VRGKCGKCPQ--QPICPFGTKPLG
GE-TRRCIYTIYFMGKRSPFIGCQPKCVKTVITRACCAGFFGPQCQPCPGKGQ-DVCFGN
GICLDGVNGTGTCECGEGFSGTACENCVEGKYGIHCDQ--ACSCVHGRCNQGLSGDGSCE
CDVGWRGVKCDSAITKDSCNGTCHTSANCLLNPDGTTSCKCAAGFQGNGTVCT----AID
ACEISNGGCSAKAYCKRTTPGSRVCVCKAGYTGDGIVCLEINPCLENHGGCDRNAECTQT
GPNQAVCNCLPTYTGDGKVCTLINACLIKNGGCSEFAICNHTGKEERTCTCKSNYTGDGF
TCRGNIYQELPKDPKTSQYFFQLQEHSV

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RDLAGPGPFTVFAPLSAVFDEDLRLKA--WDQ
QRLMPQVLRYHVVACHELLLENLKLTPNVTSLQGEPIVISVS-QDAVYINNKAKVIASNI
ITTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1905)

PQNLLVTPRDAFGRILQNLTTVAINHG--

PF02469 // ENSGT00760000119025_0_Domain_18 (1905, 2039)

YVKFSNLLQA--SGLL
SVITDPIHTPVTVFWPTDHALQALPPEQQDFLFKQDN--RDKLQEYLKFHVIRDSKVLAV
DLPRTASWKTLQGSELSVKCGADS-GIGELFLNGQMCRIVQRELLFNLGVAYGIDCLLMD
PTLGGRCDTFTTFNVSGDCGSCINTPR-CPTWSKPKGVKQKCVYQLP-LLKRKVDGCRQQ
CTLVIPV-LKCCKGYFLPDCQACPGGPDTPCNHRGVCLDSYSATGQCKCNTGFNGTACEL
CWPGRFGPD-CQACSCSEHGQCDDGITGSGQCLCEAGWTGRFCDT---------------
-----------------QTVLPPVCTPPCSAHATCRENNTCECNLNYEGDGVTCTVVDFC
KQNNGGCAKVARCSQKGTRVSCSCQKGYQGDGRSCTAIDPCADGLNGGCHEHATCKMTGP
GKHKCECKSHYVGDGVSCEPEKLPLDRCLQDNGQCHAD--ASCTDLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAYASQ
NCGSGVVGIVDYGPRPNKSEMWDVFCYRMK--DVNCTCKEGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------KDLLVYSNSSARGRAF-LKHLTDLSLRGTLFVPQNSGLGENETLS
GRDIEHHLANVSVILYNDLVNGTV----LRTRLGSQLLITSSRDQLHL------EETRFV
DGRAIVQWDIFASNGIIHVISTPLRAPPPPKTPTHAGLGTGIFFAVILVSGAVALGAYSY
FRLNHR-LIGFQHFESEV-DIGVGALGKQQPENISN-PMYENTA-SVPP----EPAYDPF
VDSDEQ---PLESS--DPLGL------

--KEKVKFTMGKSPGVLFLFYFLVAMKLCLTSQVQDEVKKQCDQKLLIRVKTKCVPCSLN
LDTQCPAGYTKITNG-TGTPDCR-YYLEIKTHTLSFPGCRHRCVKEFEQPECCQGHWGPD
CM-----------------ACPGGAASPCNRRGRCSQGI-TGNGTCTCQKGFGGTACEKC
AEDNLFGPDCTSVCDCVHGVCNSGITGDGRCTCLSGYKGLRCDQPIA----ECEALRCPA
NSRCAVSAEDGRQLQCTCLPNFHGDRTRCEPINPCSRKVCDPHADCAYLGPNQHQCSCQG
GYTGDGHVCLPIDPCQAAQGSCPAQSSICIYDGPGKSHCECKEH--YTNFVPGKGCSMID
ICETNNTCHKKAKCSTVAPGQIECTCQGGSMGNGFVCYGNIMERLQELNAQVGGQWQGKL
TSSLVLME-

PF02469 // ENSGT00760000119025_0_Domain_4 (430, 545)

NTYEWQLSTLGPFTVLVPT-NKGLKGTNIKDLLKNKQKAQYFVKLHIIAGQ
LNTSSLKN--TNAIYTLTGKAGEMSKGEKDNQLRIRIQGGRGKGKILQGDIIASNGILHI
IDKA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDSVEPEFESSKEKTIMSVLQANG

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSQFTSLIE----KTGLGMDLQQ--DNQPYT
IFVPSNKALSNMKAEVLDYLLSEEGSWKLLELVRYHIVSNTKLEVASLVSIEHIRTMAKQ
FIHFNRTSTGQILVSGEKMEETDIVAKNGRIYTLEGILIPPTI--VPILPHWCDETR-QV
TKGVCTGCLQ----HPCPQDPQPIRNFTEVLTCFSGEQRRDVRKNCCTRACNTTAKEPKC
CKGFFGPECR-PCPGGFSKPCSGKGQCMDGLDGNGTCVCSAAFQGLSCQFCSDP-SKYGP
QCDRECLCIYGKCDNRIDSDGTCLPGSCRTGYTGKLCEKQVVSCEPSL-QLCHAHADCQL
SNG---------------------------------------------------TVSCVC
KPGYEGDGLS-CSKVDPCAVLK-PGGCNINAECVQTGPGEHRCVCQAGWTGDGRDCSAIN
NCLLPSTGQCHQNATCIYVGPGQKRQNDCKCKDGFQGNGIECTLINSCLEQDGKCHHL--
------------------ATCEFESSRGWQCVCPMGYE-GDGRMCYGNAADELSTLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

AFNQWVNEAKINSVLSTTPNLTVLVPSLQAIENMDEDEKAFWMSESNIPTLLKYHVLTGA
YSFADFQNLSSSDMLPTSLQSKFLHLSKENGTPTLEGAHFVASDIPSTNGVIHVIDKVLT

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PLRS--AAMPRLLDRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYSLANEIEAANTYTVFAPSNDAIEN
YLKDKKSATLDEGQIRYHVVLDEKLLKNSLHNGMHRETMLGFSYQLGFFLHNSQVYINDA
PISYANVATDKGIIHGLGKVLEIQKNRCDINNTVITLKEKCRICSR--PSSCPPGTKEIA
GE-KKYCVLTENHMRQYTIQIGCKPKCAKTIISRECCAGFFGQQCQPCPGKAG-TACSGN
GVCLDGIGGTGQCQCEQGFEGTACEDCAPGRYGRACDQ--ACTCVHGRCSSGVDGDGSCE
CDLGWRGVTCDTEIKDDACNNSCHTSANCLLLSNGTAYCKCAAGFEGNGTFCT----AID
ACESSNGGCSAKAECRRTTPGSRACVCSAGYTGDGIVCMEINPCLVNNGGCDRNAECTQT
GPNQAVCNCLKGYSGDGKTCTYISLCSQNNGGCSEFAICNDTELTERTCTCKTNYTGDGF
QCRGNIFQELLRNSNTSRFYFHLQALSI

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RDISGPGPFTLFVPHTDILNSDPRVKD--WIA
KGVMAQVLRHHVVACASLLYEDLTAITNITSLQGEQIHISYS-QNSLVLNNKAEIILSDA
VGTNGVIHVINQILV

ENSGT00760000119025_0_Linker_17_18 (1876, 1907)

PSQMQDFPLKKPNNVFLSLKMVAARHG--YI

PF02469 // ENSGT00760000119025_0_Domain_18 (1907, 2038)

LFSTLLEK--NNLL
GLINDPIHKPVTLFWPTDTAIRGLPQEQQDFLFKKAN--TNQLVQYLKFHIVRDAAVLAY
QLPSSSPLKTLQGSNLSVSCGDNG-EIGALFLNEGQCKVVQRQLEFDGGIAYGIDCLLTE
PSLGGRCDSFLTLEFMGPCASCFRNSK-CPPGTKPKEGIHWCTYE---SYGLQRDGCRRN
CSMVIHI-AKCCKGYFGPDCQACPGGPETPCSGHGSCEDGYTGTGECRCHSGFNGTACEL
CVPGRYGSS-CRPCECKNNGQCDEGRSGTGRCFCETGWTGRLCET---------------
-----------------KLALPPVCSPSCSANAVCTENNTCQCKPLYDGDGITCTAAELC
KQNNGGCHKAAECRQHGVKVFCSCQKGYKGDGFACLPINPCADGFNGGCHEHAICTVVGP
GRRKCECKNSYIGDGLNCSVMQLPLDRCLQDNGQCHHD--ADCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYRLTYQQAREACANESAAVATYSQLLYAQKARYHLCS-AGWLDGERVGYPTGFSSP
NCGSGYVGIVDYGRRVNLSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YREK--EVNCTCKPGYVGDGISCSGNLLQVLMSL
PTLTNFL--------SDIMAYSNTSRKGREF-LQYLTDLSVH

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFAPNDSGLKENETLS
GRDIEYHLSNANILFYEDLTNGTA----LLTRLGKKLLITNTGGQEHQ------SKIRYV
DRSAIVEWDIIASNGIIHIISEPLKAPSEPA-PLHASTGTGIFFGICLVTGIVALIGYSY
LRFRKK-IIGFRHFKPKD-DTDTTSLDKSQPSNITN-PSYESSSTLTSP----DPTYDLF
SDSDDQ---QLMMS--DPHDAFRK---

--RRQHILNMIL-P-LIPLFLGFLVQNTCSPAEASGQ-AKRCDKKSFLTIWTECQACSTN
FAAKCPDGYVKITNGSVGVRDCR-YSFEIRTYSLSVPGCRHICRKDYLQPQCCPGHWGPH
CM-----------------ECPAGAASPCSGRGICDEGM-EGTGRCSCQEGFSGTACETC
AVDNVFGPNCSSVCNCVHGVCNSGLHGDGTCECFSAYKGPRCDTPIP----ECVALLCPE
NSRCSLSSKDETKLKCKCLPGYVGDGQHCTPINPCFKNICHPHASCSYLGPNRHSCSCQK
GYHGDGQVCLPVDPCQTNFGNCPTKSTMCKYDGPGQSHCECREH--YSDFVPGVGCSMIN
VCESKNPCHKNANCSTVAPGQTQCTCQKGYTGDGLTCYGNIMERLRELNTEPRGMWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TTFISILD-RTYGWPLRNLGPFTVLLPS-DKGLKGFDVKELLMDNEAARYFVKLHIIGGQ
MSTEQMND--TDTFYTLTGKSGEIFNRDKDNQLKLKLHGGK-MVKIIQGDIVASNGLIHV
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIEPTLLSNPQKTIMEILQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETSIGQALDEGGVGGPYT
IFVPSNEALDNMKEGTMDFLLSPKGSRKLLELVRYHIVAFIQLEVTTLISTSHIRSMANQ
IIQFNISQNGQILANDVAVQETGIVAKNGRIYTLAGVLVPPSI--IPIIPHRCDETKKEM
IPGTCVSCSL-VRLSKCPADSEPTALFTHKCVYSSRTRNM---KSGCARYCNATIKIPQC
CSGFFGPDCT-PCPGGFLNPCSGNGKCRDGLSGNGTCICDDGFQGSKCQFCSNP-NRYGP
RCNKTCLCAHGACDNRVDSDGACLSGTCREGTAGKFCNKQTSTCGPYV-YFCHIHATCKY
YNG---------------------------------------------------TASCVC
NEGYEGDGTL-CSKKDPCMGSTSRGGCSQNAECIPTGPGTHICVCQQGWTGDGRDCVEIN
NCLLPGTGGCHDNATCLYLGPG---QNECECKKGFRGNGIDCEPVITCLEQAEKCHPL--
------------------ASCQFASSGVWSCVCQEGYE-GNGLLCYGNVFMELSLLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFYQWINNASLQSMLSATLNFTVLVPSQQAIEDMDQNEKTFWLSWNNIPALIKYHTLLGT
YGVSDLQTLSSSHRLATSLQGSFLHLDKANGNITIEGASIVDGDNAATNGVIHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSVFRGYII----QYNLANAIEAADTYTVFAPNNEAIEN
YIREKKVTTLEEDILRYHVILGEKLLKNDLHNGMHRETMMGFSYLLGFFLHNDQLYVNEV
PINYTNVATDKGVIHGLGKVLEIQKNRCDKNDTTI-VRGMCGRCPQ--QAICPLGTKPLG
SNFILKCIYTIYFMGKRSAFIGCQPKCVRTVITRACCAGFFGPQCQACPGKGQ-NVCSGN
GFCLDGVNGTGTCECEQGFNGTACETCTEGKYGVHCDQ--ACSCVHGRCNQGPSGDGSCD
CDVGWRGVNCDSEITKDNCNGTCHTSANCLLNPDGKASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEVSNGGCSVQAVCKRTTPGSRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDRNAECTQT
GPNQAVCNCLPKYTGDGKT

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPLAICTHTGQDQRICTCKQNYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGSIYGELPKNPTTSQYFFQLQQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HAVRELTGPGPFTVFAPSSASFNQEPRIKD--WDQ
QGLMSQILRYHVVACQQLLLEDLKVTTNAMTLQGEPISISVS-QDTIYINNKAKVLSSDI
ISTNGVIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQHLLVTPKDASGRVLQNLTTVAMNNG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2038)

-YTRFSKLIQD--SGLL
SVITDHIHIPVTLFWPTDKALQALPLEQQNFLFHQDN--KDMLKEYLKFHVIRDTRALAS
DLPRSASWKTLQGSELSVKCGTGS-DIGELFLNGQMCRIVQRGLLFDLGVAYGIDCLLTD
PTLGGRCDTFTTFNVSGDCGSCVTIPR-CPRWSKPKGLKQRCLYSPV-PFGRSLEGCQQL
CTLVIPI-PRCCKGYFLPHCQACPGGPDTPCNNRGVCLDQYSATGQCQCNTGFNGTPL--
-----------ASCGCSEHGQCDEGITGSGQCLCEAGWTGRFCDT---------------
-----------------LTVVFPVCIPPCSVHATCMENNTCVCNLNYEGDGIMCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTQVSCSCQKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGV

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GRHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHPD--ASCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANEAASMATYNQLSYAQKASYHLCS-AGWLENGRVGYPTTYASP
KCGSNIVGIVDYGIRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKAGYVGDGFSCNGNLLQVLMSL
SSLTNFL--------EEVLAYSNSSARGQAF-LKHLTDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

RGTLFVPQNSGLLENKTLS
GRDIEHHLTNVSVSFYNDLVNGTV----LRTRLGSQLLITSSQDQLHQ-------ETRFV
DGRAILQWDIIASNGLIHIISEPLEAPPMTATPAHTGLGTGIVCAVILVTGAIGLAVYSY
FRLNQR-TIGFRHFESEE-DINVLAFGKQQAENISN-PVYESSM-PAPP----ETSGDPF
TDSEEQ---EEESS--DPLGAQRS---

---------MLQ-H-LVIFCLGLVVQNFCSPAETTGQ-ARRCDRKSLLTIRTECRSCALN
LRVKCPDGYTKITNGSVGVRDCR-YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPD
CI-----------------ECPGGAESPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP----ECAALLCPE
NSRCSPSTEDENKLECKCLPNYQGDGKYCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPRAHCTYLGPNRHSCTCQE
GYRGDGRVCLPVDPCQTNFGNCPTKSTVCKYDGPGQSHCECKKH--YHNFVPGMGCSMIN
ICKTNNLCHRNANCTTVAPGQTQCICWKGYVGDGLTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSKLGPFTVLLPT-DEGLKEFNVNELLVDNKAAQYFVKLHIIAGQ
MNIEYMNN--IDTFYTLTGKSGEIFNSDKDNQIKLKLYGGKNKVKIIQGDIIASNGLLHI
LDRT

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDMLEPIFESNNEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----KTNVGHALDKDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFTTTDNGQILANDVAMKEIEITAKNGRIYTLTGVLIPPSI--VPILPHRCDETKREM
KLGTCVSCSL-VYWSRCPANSEPTALFTHRCVYSGRFGSL---KSGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADSLAGNGTCICKEGFQGSQCQFCSDP-NKYGP
QCNKKCPCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SSG---------------------------------------------------TVSCVC
KAGYEGDGTV-CSEMDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCLEIN
NCLLPSAGGCHDNATCLYVGPG---QNECECKKGFRGNGIDCEPVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTRKCHPL--
------------------ANCQSTSSGIWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHILLGT
YRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVNGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PRRRLTGSLPNLLMRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAADAYTVFAPNNDAIEN
YIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRKTMLGFSYFLGFFRHNNQLYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-IRGRCRTCSS--ELICPFGTKPLS
KE-KRRCIYTSYFMGRRTLFIGCQLKCVRTVITRECCAGFFGPQCLPCPGNAQ-NVCFGN
GICLDGVNGTGVCECEEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCENVTTEDDCNGMCHTSANCLPNSDGTASCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNHTGQGERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1765)

CRGNIYQELPKNPKTSQYFFQLQ

PF02469 // ENSGT00760000119025_0_Domain_17 (1765, 1876)

EHFVKDLVSPGPFTVFAPLSAAFDEEARVKD--WDK
QGLMPQVLRYHVVACHQLLLENLILISNATSLQGEPIVISVS-QGTVYINNKAKIISSDI
ISTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKNLLITPKDTSGRILQNLTTLATKNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDRALQALPAEQQDFLFNQDN--KDKLKEYLKFHVIRDAKVLAV
DLPTSTAWKTLQGSELSVKCGAGS-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTAFHALGLCGSCVNTPS-CPRWSKPKGEKQKCLYN-L-PFKRNLEGCREW
CSLVIQI-PRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSGTGMCKCNTGFNGTACEM
CWPGRFGPN-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT---------------
-----------------QAVLPAVCTPPCSPHATCKENNTCECNLNYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGLS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--AKCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAKEACANETATMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2563)

YRMK--DVNCSCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLTDLSIR

PF02469 // ENSGT00760000119025_0_Domain_27 (2563, 2664)

GTLFVPQNSGLGENETLS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITASHDPLQP------TETRFV
DGRAILQWDIFASNGIIHIISRPLKAPPAPMSLTHTGLGAGIFFAVILVIGAVALAAYSF
FRLNRT-TIGFQHFESEE-DINVVAVGKQQPENISN-PLYESTT-SAPP----EPSYDPF
TDSDER---QLEGN--DPLGTL-----

--------VMLQ-H-LVILSLGLVIQTFCSVTVLRGK-GRRCDMPTFLLVKTECQSCVLS
LNVKCPDGYDKLTK-AEGFRDCR-YTFKVRQSSLLLPGCRHLCKKNYVEPRCCSGHWGPD
CM-----------------ECPGGWQSPCSGRGTCAEGM-NGSGTCSCQEGFGGTACETC
ANDSLYGPNCSQVCNCVHGVCSSGLHGNGTCTCYSAYTGPSCDKPI-----ECAALLCPE
NARCSPSSKDASKLECKCLPNYKSNGKDCEPINPCLRNVCHPHARCTYLGPNQHNCTCQE
GYYGDGQACLVLDPCQVNFGNCPKQSTVCRFDGPGQSYCECKEH--YHKFVPGVGCSMIN
LCEINNPCHKNANCTTTAPGKTECTCQKGHVGDGMACYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

SL
TSFIALLD-KVYAWPLSNLGPFTVLLPT-DKGLKGFNIKALLLDKEAAEYFVKLHIIAGQ
MSTTRMNA--TDTFYTLTGKSGEIFIDDTGNQL--KLYEAKNRVKIIQGNIIASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

ELAPTLKSNTEQTIMEMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETSVGHALDEDRFGEAYT
IFVPSNEALENMKDGTLDYLRSPEGARKLLELVRYHIVPFTQLKVATLIATPHIKSMANQ
IIQFNTTENGQILANGVAIEETEVSAKNGLIYTLSGVLIPPSI--IPILPHRCDETKREM
TLXXXXXXXX-XXXXXXXXXXXXXSLFKHRCVYSR-MRV---LKLGCARFCNATKKXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXCLCVQGTCDNRIDSDGSCHAGTCRDSSAGRFCDKQTSVCGPYV-HFCHIHATCEN
SNG---------------------------------------------------TVSCVC
-AGYDGDGFI-CSEIDPXXXXX-XXXXXXXAECMQTSSGTHSCVCQQGWTGNGRDCVEIN
N

PF00008 // ENSGT00760000119025_0_Domain_9 (1022, 1062)

CLLPGAGGCHSNATCLYVGPG---QNACECKKGFRGSGIN

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPIIS

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGTCHPL--
------------------ATCQPTASGVWSCVCQEGYE-GNGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAAVELSSLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

EAA
AFNQWIYNASLQPMLSTTLNLTLLVPSHQAIEDMDQVAKSFWLSQSNIPALIKYHTVLGT
YGVEDLQTLSASDTLATSLQDHFLRLEKVDGNITIEGASIVDGDNAATNGVIHIINKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLSSSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYTIFRGYLM----RYNLVNTIEAASTYTVFAPNNNAIEN
YIREKRVTTLGEDIIQYHVVLDEKLLKNDLHPGMHRETMLGFSYLLGFFFHNNQLYVNEA
PINYTNVATDKGVIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1485)

IQKNRCDNNDTTI-IRGKCGTCSQ--KPVCPLGTTPLG
NE-TKRCIYTLYFMGKRSMFIGCQAKCVKTVITRACCAGYFGPQ

PF00053 // ENSGT00760000119025_0_Domain_13 (1485, 1542)

CQACPGKGQ-NVCFGN
GICLDGINGTGTCECGEGFGGTACESCAEGKYGIHCDQ--A

ENSGT00760000119025_0_Linker_13_14 (1542, 1622)

CSCVHGRCNQDLSGDGSCE
CDVGWRGVRCDSAITKDSCNGTCHTSANCLPNPDGTGSCKCAAGFRGNGTICT----AID
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CELSNGGCSAKAYCKRTTPGSRVCLCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAACNCLPTYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINI

PF00008 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLIKNGGCSEFAICNQTGKDKRTCTCKINYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1755)

CRGNIYQELPRDP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQFFFQLQEHSMRELAGPGPFTFA--PSSAFNEDLRIRD--WHQ
QGLMPQVLRYHMVACHQLPLESLKQTPNVTSLQGEPIVVSIS-QGAVYLNKRAKVIASDF
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLVTPRDASGHILQNMTAVAIKHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YIKFSNLLQD--SGLL
RVILDPIHTPVTVFWPTDKALQALPAEQQDFLFRQDN--KDRLKEYLSFHVIRDSKXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXGELFLNGQMCRIVQRELLFDLGVAYGIDCLLMD
STLGGRCDAFKTFTLSGGCGSCLSTPK-CPSWSKPKVAKDKCEYQLP-QLKRTVQGCKHQ
CTLVIRL-RRCCRGYFLPDCQACPGGPDTPCNNRGTCVDHYSPTRQCASNIGFNGTACEL
CLTGRFGPD-

PF00008 // ENSGT00760000119025_0_Domain_21 (2171, 2203)

CHPCNCSKHGQCDDGIGGSGQCLCEAGWTGRFCNT---------------
-----------------QTAFPPVCTPPCSAHATCKENNTCECNLNYEGDGVTCTVVNF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
DQNNGGCAKVARCSQKGTKVSCSCQKGYQGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CIAVDP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGLNGGCHEHATCRMTGP
GKHKCECKSHYVGDGVNCEPEKLPLDRCLQDNGQCHAD--ANCADLHFQXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00193 // ENSGT00760000119025_0_Domain_26 (2432, 2487)

XXXAKYHLCS-AGWLESGRVAYPTAYASP
NCGSGVVGIVDYGPRANKSEMWDVFCYRMK--DVNCTCKAGYVGDGFSCSGNLLQVLMSI
PSLTNFL--------KDVLAYSNSSIRGQEF-LKHLTDLSFRGTLFVPENSGLGENETLS
GRDIEHHLTNVNIFFYDDLVNGTI----LQTRLGSQLLITSSQDQSQL------KETRFV
DGRAIVQWDIFASNGIIHVLSRPLRAPSGPKTSTHTGFGTGIFLAIILILGAVALGAYSY
FRLNHR-PIGFQHFKSEE-DIDVGALSKQQPENISN-PMYESTT-SVLP----DPAYDPF
VDSDEQ---PLESS--DPLGAL-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------GYVGDGSTCYGNIMERLRELNTGPGGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVKELLMDNEAAKYFVKLHIIAGQ
MNTEQMNS--TDTFYTLTGKAGEIFNDDKDNQLKLKLYGGKKKVRIIEGDIIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

LDRIAPTFESNTEQTIMAMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEDGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLDVATLLSSPRIRSMANQ
VIQFNITDSGQILANDVAMEETEVAAKNGRIYTLSGVLIPPSI--VPILPHRCDETKREL
KLGTCVSCSL-VYWSKCPPNSERTALFTHRCIYRT--RTM---KSGCARYCNATVQIPKC
CKGFYGPDCS-QCPGGFSNPCSGNGQCVDGLHGNGTCICEDGFQGSQCQFCSDP-NKYGP
RCDKKCLCIHGTCDNRIDSDGACLTGTCRDGSAGRFCDKQPSACGPFV-QFCHIHATCEY
GNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSEMDPCTGST-SGGCSRNAECIRTGLGTHACVCQQGWTGSGRDCVEIN
NCLLPS

PF12947 // ENSGT00760000119025_0_Domain_9 (1027, 1062)

AGGCHPNATCLYVGPG---QSECECKKGFRGSGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPITS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ARCQLSPSGVWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1141)

CYGNAAVELSFLSEAV

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

IFSQWIHNASLQAMLSAAPNLTVLVPSQQAIEDMHQDEKAFWLSQSNMPALVKYHTLPGM
YRVADLQSLSSSDMLATSLQGNFLHLAKVDGNVTIEGASIIDGDNAAINGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLAGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

NYSIFRGYII----QYNLASAIEAAETYTVFAPNNDAIEN
YIRQKKAASLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLGVSYLLGFFLRNDQLYVNEA
PVNYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-VRGKCGQCPQ--QPVCPLGTKPLG
NE-TRTCIYTIYFMGKRSLFIGCQPKCVKTVITRECCAGFFGPQCQPCPGGTQ-NVCFGN
GVCLDGVNGTGACECGGGFQGTACETCTEGKYGIHCDQ--ACSCAHGRCNQGPSGDGSCD
CDVGWRGVHCDSVITKDACNGACHSSANCLLGPDGTASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCACKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAVCNCLPTHTGDGKF

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTFINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICNYTGTEERTCTCKPNYVGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1802)

CRGSIYQVNLTS-----------------------LNVF--------AKYELKD--WDR
Q

PF02469 // ENSGT00760000119025_0_Domain_17 (1802, 1876)

GLIPQVLRYHVIACQQLLLENLKLTPNATSLQGEPIVFSIS-QGTVYINNKAKIISSDI
ICSNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLILTPKNASGRIVQNLTTVATNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSNLIQD--SGLL
SVITDPIHTPVTLFWPTDQALQALPSEQQDFLFNQDN--RDKLKGYLKFHVIRDSKILAV
DLPKSAAWKTLQGSELSVTCGAGS-DIGELFLNGQTCRIVQRELLFDLGVAYGIDCLLID
PTLGGRCDTFTTFNVSGDCGSCSNIPS-CPRWSKPKGEKQKCLYN-L-PFKRNAEGCRQQ
CGLVIRL-PRCCKGYFGRDCQACPGGPEAPCNNRGVCLDQYWATGECQCNIGFNGTACEM
CWPGRFGPD-CQSCGCSDHGQCDDGITGSGQCFCETGWTGRFCYT---------------
-----------------PTDLPPVCTPPCSAHATCKENNTCECNLNYEGDGLTCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKGATCSQKGTKVSCSCQKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCTMTSP
GKQKCECKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPVDRCLQDNGQCHPD--ANCADLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLDSGRVAYPTAFASQ
KCGSGMVGIVDYGPRPNRSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2562)

YRMK--DVNCTCKVGYVGNGVSCSGNLLQVLMSL
PSLTNFL--------TEVLAYSNSSARGRAF-LEHLSDLSI

PF02469 // ENSGT00760000119025_0_Domain_27 (2562, 2664)

QGTFFVPQNSGLGENETLS
GQDIEHHLVSVSTVFYDELVNGTT----LRTRLGSQLLITSSQDPLQP------KETRFV
DGRAILQGDIVASNGIIHIISRPLKAPATPVTSAHTGLGTGIFFAVILVAGAIALAAYSH
FRLSRR-GTGFQRFESEE-DIDVAALGNRPPENISN-PMYESVA-AAPP----EPSYDPF
VDSDEL---QLESS--DPLGAL-----

--------IMLQ-Y-LVIFCLGLVVQTFCFSAETAGQ-TRRCDQKSLLTIRTECRACFLN
LEVNCPDGYTKITNENKCAE------------------------------------TLFD
SL-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ADDTLFGPSCSAVCNCVHGVCNSGLDGDGTCECYSAYTGPTCDKPIP----ECAALLCPE
NSRCSPSSEDETKLECKCLPNYQGDGKSCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCTCQE
GYHGDGQVCLPVDPCQRNFGNCPTNSTVCKYDGPGQSHCECKEH--YHNFVPGVGCSMTN
ICESNNLCHKNANCITIAPGQTECTCQKGYVGDGFTCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFISILE-KAYAWPLSNLGPFTVLLPT-DNGLKEFSANELLVDNKAAQYFVKLHIIAGQ
MSTEYMNN--TDTFYTLTGRSGEIFNSDKENQINLKLYGGKKKVKIIQGDLIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNLEPTFESNDEQTIMTMLQT--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEEGVGGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQ
LIQFNTTDNGQILANNVAMEEIEITAKNGRIYTLTGVLIPPSI--IPILPHRCDETKREM
KLGTCVSCAL-VYWSRCPADSEPTALFTHRCVYSSRFRSP---KSGCARYCNGTVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLGGSGTCICEEGFQGSQCQFCSDP-NKYGP
RCSKKCLCVHGTCDNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSETDPCTGLT-PGGCSRNAECIKTGTGTHTCVCQPGWTGNGRDCVEIN
NCLLPSAGGCHNNATCLYVGPG---QNECECKKGFRGNGIDCEPITSCLEQTGTCHPL--
------------------ANCQFTTSGVWGCVCQEGYE-GDGFLCYGDAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPSLIKYHTLLGS
YRVADLQTLSSSDVLATSLPGSFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRALTGFLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLANAIEAANAYTVFAPNNNAIEN
YIREKKVLSLEKDVLRYHVVLEEKLLKNDLHNGMHRETMLGFSYLLGFFLHNDQIYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-VRGRCTTCSA--QQLCPSGAKPLD
NE-IKRCIYTIYFMGKRALFIGCQPICVRTVITRECCAGFFGPQCQACPGNTQ-NVCSGN
GICLDGVNGTGVCECEDGFKGTACETCSEDKYGIHCDQ--ACSCVHGRCNQGLLGDGSCD
CDVGWRGVHCDEG------------KSDCIL-TDGTPSCKCAAGFQGNGTICT----AIN
P

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSAKADCKRTTPGRRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSKFAICTHTEQGERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1767)

CRGSIYQELPKNPKTSQYFFQLQEH

PF02469 // ENSGT00760000119025_0_Domain_17 (1767, 1876)

SVKDLDNPGPFTVFAPSSAAFHEEALVTD--WDK
QGLMPQVLRYHVIACQQLLLENLKLISNATSLQGEPVVISVS-QGTVYLNNKAKIISSDI
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1907)

PQNLVITPKDTSGRILQDLTTLATNNG--YI

PF02469 // ENSGT00760000119025_0_Domain_18 (1907, 2039)

KYSKLIQD--SGLL
SVITDPIHTPVTLFWPTDQALQALPAEQQDFLFNQNN--KDKLKQYLKFHVIRDAKILAV
DLPRSPSRRTLKGSDLSVKCGTGN-NIGDLFLNGQKCRIVQRELLFDRGVAYGIDCLLID
PTLGGRCDFFTTLNILGNCGSCFNTPS-CPKGSKPKGVRQKCLYN-L-SFRRNLEGCRQQ
CSLVIQI-PNCCEGYFGRDCQACPGGPETPCNNRGVCHDHGY-TGECKCNTGFNGTACEM
CSPGRFGPD-CLPCRCTDHGQCYDGITGSGQCFCETGWTGPLCDT---------------
-----------------QAVLPAVCTPPCSVHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVATCSQKGTKVSCSCQKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCTMTGP
GKHKCQCNSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQVPFDRCLQDNGQCHAD--ADCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANEAATIATYSQLSYAQKAKYHLCS-AGWLEGGQVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2554)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TKVLTYSNSSARGRTF-L

PF02469 // ENSGT00760000119025_0_Domain_27 (2554, 2664)

QQLTDLSIRSTLFVPQNSGLAENEALS
GRDIEHHLANVSMFFYNDLVNGTT----LQTRLGSKLLITAGQDPSQQ------TEARFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPVTSAHTGLGAGIFFAIILVIGAVALAAYSY
FRLNQR-TIGFQHFESEE-DINVAALGKQQPESISN-PMYESTT-SAPP----EPSYDPF
TDSDER---QLEGS--DPLGAL-----

-----------------------------------SQ-AKRCDKKSLLTIRTECQSCSLN
LGIKCPDGYTKVTNGSVGVRDCR-YIFEIRKYSLSLPGCRHICRKDYVQPQCCPGHWGPD
CM-----------------ECPGGASSPCSGRGSCAEGM-EGNGSCSCQDGFGGTACETC
ADDNLFGPSCSAVCSCVHGVCNSGIDGDGSCDCYSAYTGPNCDKPIP----ECAALLCPE
NSRCSPSSQDERKLECKCLPNYQGDGHYCEPINPCLQAVCHPHAHCTYLGPNQHSCTCLE
GYHGDGQVCLPVDPCQTHYGNCPTESTVCMYDGPGQSHCECKEH--YRNYVPGVGCSMID
V

PF00008 // ENSGT00760000119025_0_Domain_3 (362, 397)

CESNNPCHRNANCTTIAPGQPKCTCRKGYVGDGST

ENSGT00760000119025_0_Linker_3_4 (397, 419)

CYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

SL
TTFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVKELLMDKEAAQYFVKLHIIVGQ
MNTERMNN--TDTFYTLTGKSGEIFNGNKDNQIKLKLYGGKKKVKIIQGDIVASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KMAPTFESNTEQTIMTLLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHTLDEDGTDGPYT
IFVPSNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVGTLIVTPHIRSLANQ
IIQFNTTNNGQILANDVAIEETEVIAKNSRIYTLTGVLI

ENSGT00760000119025_0_Linker_5_6 (700, 793)

PPSI--VPILPHRCDESKREM
KLGTCVSCSL-VYWSKCPANSEPTTLFTHRCVYTGRIRSL---KSGCARYCNATVEIPKC
CKGFYGPDCN-Q

PF07974 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSNPCSGNGQCVDGLDGNGTCICQDGFQGSQ

ENSGT00760000119025_0_Linker_6_7 (828, 884)

CQFCSDP-NKHGP
RCDKECLCIYGTCDNRIDSDGACLAGTCREGSAGMFCHKQTSA

PF00008 // ENSGT00760000119025_0_Domain_7 (884, 972)

CGPYM-HFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGSL-

ENSGT00760000119025_0_Linker_7_8 (972, 978)

CSETDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CAGTT-PGGCSRNAECIRTGVGAHTCVCQQGWTGDGRD

ENSGT00760000119025_0_Linker_8_9 (1016, 1022)

CSEIN
T

PF00008 // ENSGT00760000119025_0_Domain_9 (1022, 1062)

CLLPGTGGCHANATCLYVGPG---QNECECKEGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEAVTS

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGNCHPL--
------------------ATCQFTSSGLWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAAVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

AAA
IFNQWINNASLQPMLSAASNLTVLVPSQQAIKDMDQDEKTFWLSKSNIPALIKNHVLLGM
YGVADLQALSPSDMLATSLPGNFLHLAKVDGNITIEGASVIDGDNTATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRSLTVSLPNLITRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QYNLASAIEAANTYTVFAPNNNAIKN
YIQEKKVATLEEDVLRYHVILEEKLLKNDLHHGMHRETMLGFSYLLGFFLHDDQLYVNEA
PINYTNAATDKGVIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1488)

IQKNRCDNNDTTI-VRGKCGACLQ--QPICPFGTKQLG
EE-IRRCIYTIYFMGKRSLFIGCQPKCVKTIITRECCAGFFGPQCQA

PF00008 // ENSGT00760000119025_0_Domain_13 (1488, 1524)

CPGKAE-NVCFGN
GICLDGVNGTGVCECGEGFAGTA

ENSGT00760000119025_0_Linker_13_14 (1524, 1622)

CESCTEGKYGPHCDQ--VCSCVHGRCNQGPSGDGSCD
CDAGWRGVRCDTGKGESLRTAFALSNCSCLLNPDGTASCKCAAGFQGNGTVCT----AIN
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSAQADCKRTTPGSRQCVCRAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCHKNAECTQT
GPNQAVCNCLPKYTGDGKVCSFINTCLTKNGGCSEFAICNHTGPEERTCTCKAEYTGDGF
TCRGNIYQELPRNP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQYFFQLLEHSVRDLSGPGPFTVFAPLSAAFDEEPQIKD--WDK
KGFMPQVLRYHVIACHQLLLENLKLIPNATTLQGEKIFISVS-QDTVYINNKAKIISSDI
IHTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLITPRDASGRILQNLTTVAVNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YTKFSSLLQD--VGLL
GVITDPVHTPITLFWPSDQALQALPPEQQDFLFNQEN--KDKLMEYLKFHVIRESKILAV
GLPRATAWKTLQGSELRVTCGAGG-DIGELFLNDQTCRIVQRELLFDLGVAYGIDCLLI

ENSGT00760000119025_0_Linker_18_20 (2040, 2123)

D
STLGGHCDTFAAYNFSGDCWSCANTPS-CPKWSKSKGVKEKCRYY-S-AFSGYLEGCREQ
CTMVLRL-PKCCKGYFGRDCQA

PF07974 // ENSGT00760000119025_0_Domain_20 (2123, 2158)

CPGGADTPCNNHGFCLDQYLGIGECRCHMGFNGTA

ENSGT00760000119025_0_Linker_20_21 (2158, 2171)

CEL
CLPGRFGPD-

PF00008 // ENSGT00760000119025_0_Domain_21 (2171, 2203)

CQSCGCSAHGQCDDGITGSGQCFCETGWTGRFCNT---------------
-----------------QTALAPVCTPSCSAHATCKENNTCECNLNYEGDGITCTVVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTKVSCSCLKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CTEIDP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGLNGGCHEHATCKMTGP
GKHKCECKSHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2394)

CEPEQLPVDRCLQDNGQCHAN--AECADLHFQDTTL

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAREACANEAASMATYNQLSYAQKAKYHLCS-AGWLESGRVAYPTAYASQ
NCGSGVVGIIDYGQRNNKSEMWDVFCYRIK--DVNCTCKAGYVGDGFSCSGNLLQVLMSV
PSLTNFL--------TEVLAYSNSSARGRAF-LNHLTDLSIRNTLFVPHNSGLGENETLS
GRDIEHHLASVRVFFYNDLVNGTV----LRTTLGSQLLITSSQDRRQP------QETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPAPLASAHTGMGTGIFFATILVFGAATLAAYSY
FRLSRR-AAGFQHFESEE-DIDVAALGKQQPENIPN-PLYESTP-SAPP----EPSCDHF
---------------------------

---------MRKSL-KPSILIGFILHLLCSLAETLEQ-ANRCDKKTLITTRTECQSCSLN
LHINCPDGYTKVTNGSSGVRDCR-YSFKVRDYALSLPGCRHICRKEYVQPLCCPGFWGPD
CM-----------------ECPGGKKSPCSGRGHCSDGI-EGNGSCICSEGFGGTACETC
VEENLFGLNCTSVCNCVHGVCNSGLDGDGTCLCYSAYTGPNCDKPIP----ECEALLCPE
NSRCSTSSMDESILECKCIANYKGDGWHCEPINPCLERVCDVNAHCTYLGPNRHQCTCQD
GYKGDGQVCVPIDPCQEDFGGCPTQSTVCQYDGPGQSHCECKEH--YQSFVPGLGCSLMD
LCESRNPCHKNANCSMRGPGQTECTCQKGYVGDGSMCYGNIMEQLQNLNTEPRGQWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

KL
TSFISLLD-KAYAWPLSNLGPFTVLVPT-NKGLKGTNVKELLTDKENAQYFVKLHIIAGQ
VDTEGLNS--TDTFYTLTGKLGEIFSGDKDNQLRLKLSGGKKKGKIVQGNIIASNGILHI
IDKA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKMAPVFESNTEQTIMAMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----VTNVGHALDEDGVGGPYT
IFVPSNEALNSMKDGVLDYLLSAEGSRKLLELVRYHIVPFTQLEVANIISKPHIRTMANQ
IIQFNTTSNGQILANEVAMEEVEVAAKNGRIYTLAGVLIPPSI--VPILPHRCDETQREM
KLGTCVSCSM-VYWSVCPANSVPLSLFTSNCVYGRKIGSQKFPTKGCARYCNATVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCADGLSGNGTCICDNGFQGSRCQFCSDP-RKYGP
QCEKKCLCVHGTCDNQIDSDGACLLGTCKDGSAGQFCDKQTTACGPYV-HFCHIHARCEY
SSR---------------------------------------------------TARCVC
NQGYEGDGTI-CTEVDPCAGII-PGGCSINAECVKTGTGTHTCVCQPGWTGDGRDCSAIN
NCLLPNFGGCHDNATCLYVGPG---QHNCECKAGFRGNGIDCEPITSCLEQTKKCHPL--
------------------ATCQSTSSGLWSCVCQDSYE-GDGIMCYGNVAVELSLLSEAA
L

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNQWVNEASSQAMLSGTSNLTVLVPSQQAIENMDQAEKTFWLSKNNIPTLIKYHALVGT
YRTSDLQILSSSDMLATSLQGNFLHLSKVNGNITIEGANIVDSDNAATNGVIHIIDKVLL

ENSGT00760000119025_0_Linker_11_12 (1261, 1295)

PQRSMSASLPNLLTRLDQMPDYSIFRGYIIASIH

PF02469 // ENSGT00760000119025_0_Domain_12 (1295, 1401)

QYSLANAIEAADAYTVFAPNNDAITN
YIREKTTTTLEENILRYHIILEEKLLKNDLHNGMHRETMLGVSYLIGFFLQNGQLYVNEA
PVNYTNVATDKGVIHGLGKVLEIQKNRCDSNYTTI-LRGRCEYCLR---KHCPPGTKPVE
EE-AKKCIYMTYFMGKRSMHIGCQTKCIKTVITKECCAGFFGPQCQLCPGKAG-NACFGN
GICLDGVNGTGVCECEGGFSGTACETCTEGKYGSNCDQ--VCGCVHGQCSQGPSGDGSCE
CDVGWRGVKCDSEIKDDDCNKTCHTSANCLLSSDGTAYCKCAAGFQGNGTACTGKSIPID
ACETSNGGCSGQADCRRTTPGNRVCVCKAGYTGDGIVCLEINPCLENNGGCDQNAECTQI
GPNQAVCNCLRGYTGDGKTCTLINICLTKNGGCSEFAVCNHTALDERTCTCKPGYKGDGF
ICRGPIYLELPKNAQTTPYFIHLQEN

PF02469 // ENSGT00760000119025_0_Domain_17 (1767, 1876)

AIRDLMGSGPFTVFVPFGEAFENASQVKE--WTT
QGVLPQILRYHVVSCHQLLLENLKLSPSITSLQGEALQITVS-QDTVYLNGKAKIVSSDT
ICSNGVIHIIDQLLV

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PKKLQAIHKDASGNNMENLTSVAIHQG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

LRFSSMLQD--AGLL
SFINDPIHKPVTLFWPTDKALEALPQEQQDFLFSKDN--KDKLKDYLKFHIIRDSKILAV
DLPGVASRKTLQGSELSVKCGD-D-NIGDLLLNDQKCRIVQRQLEFDSGIAYGIDCMLIN
PSFGGRCDSFITFNVSGDCGSCYNIPR-CPTWSKPKGVKQKCFYH-L-PFRRNLEGCQQK
CTMIMRL-PKCCKGYFGRDCQACPGGPRTPCNNRGICTDEYFGAGECKCNTGFNGTACEL
CWPGRYGPD-CKPCDCSEHGSCDDGITGSGDCFCETGWTGRFCDS---------------
-----------------QLALAPVCTPPCSKYATCKENNTCECNLHYEGDGITCTVVDFC
KQNNGGCSKVAKCSQTGTKVTCSCQKGYKGDGHICNAVDPCADGLNGGCHEHAVCTMTGP
GKHRCECKSHYVGDGLDCVVEQLPIDRCLQDNGQCHAD--ANCADLHFQDATIG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PRGQYKLSFDEAKEMCTKEEATVATYIQLSYAQKAKYHLCS-AGWLNDGRVAYPTAYSSQ
NCGSGFVGIVDYGPRPNKSELWDVFCYRVK--DVNCTCKVGYVGDGFACSGNLLQVLMSF
PSLANFL--------SEVLVYSNSSSRGKAF-LKHLTDLSIQGTLFVPNNDGLWENKTLS
GRDIEHHLSNSSTLFYEDLANGTT----LQTRLGGQLLITYGQDIHHT------NETRLV
DGQVILQWDIIASNGIIHIISGPLKAPPVPNVSAHAGLGAGVFFTIILVIGAIALAVYSY
FRINRR-TIGFQHFEPEE-DIDVTSLGKQPSSNISN-PMYESATTPPPP----EPAYDPF
ADSDEQ---QLVTS--SPQEL------

TRRSQHFLNMLP---LRMVLLGLIGQTFCSLAETTGQ-AKRCDKESLLTIKTECLSCSIN
FGVECPAGYTKITNNSIGVRDCR-YTFEIRTYSLRLPGCRHICRKNYLEPECCPGHWGPD
CM-----------------ECPGGAESPCSGRGRCADGI-ERDGSCSCQEGFGGTACETC
ADDNLFGPTCSEVCNCVHGVCNRGLEGDGTCECYSAYTGPSCDQPIP----ECAALLCPE
NSRCAPSDEDETKLECKCLPNYKGDGKSCEPINPCLQN

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

VCHPHADCTYLGPNQHSCTCKD
GYRGDGHVCLPVDPCQTNFGNCPIKSTVCKYDGPGQSHCECKEH--YQNFVPGVGCGMIN
ICESNNPCHRNANCTTVAPGQTECTCQKGYVGDGATCYGNIMERLRELNTEPRGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPS-DKGLKGFNVKELLMDIKAARYFVKLHVIAGQ
MSTEHLNN--TDTFYTLTGASGEIFNRDKDNQLKLKLYRGKKKVKIIQGNIIASNGLVHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDKIEPTFESNTQQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGQALDKDGIGGPYT
IFVPSNEALDNMKEGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVANLVSTPHIRSMANQ
FIRFNTSSNGQLLANDVAMEEIEVAAKNGRIYTLAGVLIPPSI--VPILPHRCDETKREM
KLGSCVSCSL-MYWSKCPANSEPTALFTQKCVYRGRT-GL---KSGCTRYCNATVQVPKC
CRGFYGPDCS-PCPGGFSNPCSGNGQCADGRSGNGTCMCDDGFQGSRCQFCSDP-SKYGP
RCNKKCLCVHGTCDNRIDSDGACLAGTCTDGSAGRFCDKQTSACGPYM-QFCHIHATCEF
SNG---------------------------------------------------TASCVC
KEGYEGDGVQ-CSERDPCVGST-PGGCSRNAECIKTSTGTHTCVCQQGWTGNGRDCVEVN
NCLLPGRGGCHNNATCLYVGPG---QNECECKKGFRGNGIDCEPIIS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQFASAGVWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGNAAMELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
IFNQWINNASLRLMLSTTSNLTVLVPSQQAIENMDQDEKIFWLSQSHIPALIKYHTLLGT
YGVADLQNLSSSDMLATSLQGNFLHLEKVDGNITIEGASIVDGDNAATNGVIHIISKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYNLAGAIEAADAYTVFAPNNDAIVN
YIREKKVTTLEEDVLRYHVVPEEKLLKNELHQGMHRETMLGFSYLLGFFLHNGQLYVNEA
PVNYTNVATDKGVIHGLGKVLEIQRNRCDINDTII-VQGKCGKCLQ--TPICPLGTKPLG
DE-TKKCIYTIYFMGKRSVFIGCRPKCVKTTITRACCAGFFGPQCQACPGRPQ-NVCFGN
GICLDGVNGTGVCECDQGFSGTACETCTEGKYGIHCDQ--ACPCVHGRCNQGPSGDGSCE
CDVGWRGVRCDSAITVDNCNRMCHTSANCLLNPDGTASCKCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSANAICKRTTPGSRVCVCKEGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAACNCLPKYTGDGKT

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINI

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTNNGGCSPFAFCNHTTKDERTCTCKENYTGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1766)

CRGNIYQELPKNPETSQYFFQIQM

PF02469 // ENSGT00760000119025_0_Domain_17 (1766, 1876)

HVIRELAGPGPFTLFVPVSKAFDKEPRIQD--WDK
QGLMPQILRYHVVACQQLLLENLKSTPNATSLQGEQIVISVS-QDTVYLNKKAKIISSDI
ITTNGIVHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLITPRDASGKILQNLTTLAATHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YNRFMKLIQD--SDLM
SVITDPIHTPVTLFWPTDQALQALAPEQQNFLFNQVN--KEKLKEYLKFHVIRDSRISAA
DLPRR-AWNTLQGSELSVKCGTDR-DIGELILNDQMCRVVQRELLFDLGVAYGIDCLLMD
PTLGGRCDTFTTFNVSGDCGSCVNTPR-CPRWSKPKGVKQKCLYNLL-PFKRNLEGCQQQ
CMLVIQL-PRCCKGYFLPDCQACPGGPDTPCNNRGVCLEEYSATGQCQCNIGFNGTACEL
CWPGRFGPE-CQPCSCSEHGQCDDGIAGSGQCVCEPGWTGRFCDI---------------
-----------------QAELAPVCTPPCSAHATCMENNTCECDLGYEGDGVTCTAVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKAAKCSQKGTKVSCSCLKGYKGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CVEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GKHKCECKSHYVGDGQD

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPLDRCLQDNGQCHAD--AECTDLHFQDSTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFAKAREACANEAATMATYNQLSYAQKAKYHLCS-AGWLDSGQVAYPTAYSSK
KCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2564)

YRMK--DVNCTCKTGYVGDGFSCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGQAF-LKHLTDLSIRG

PF02469 // ENSGT00760000119025_0_Domain_27 (2564, 2664)

TLFVPQNSGLGENEILS
GRDIEHHFTNVSILLYNDLVNGTM----VQTRLGSQLLITSGHNQLQ-------METRFV
DGRAILQWDIVASNGVIHVISRPLKAPSTPATSTHTGLGTGIFFGIILVIGAIASAAYSY
FRLNWR-TVGFQHFESEE-DIDVAAFG--QPENISN-PVYESAT-SAPP----EPSCDPF
ADSGEP---QLESG--DPLGAMRT---

AGTRAVALVMPR-G-LAAFLLGLLVAGVGSPPEAAGQ-ANRCDKKSLLTIRTECQSCSLN
LGINCPDGYTKVTNGSMGVRDCRRYAFDIRKYSLYLPGCRHICRKDHVQPQCCPGHWGPN
CM-----------------ECPGGARSPCSGRGSCAEGM-EGNGRCSCQDGFGGTACEAC
AHDNLFGPNCSAVCSCVHGVCNSGIDGDGSCECYSAYTGSHCDQPIP----ECADLLCPE
NSRCSPSSQDETKLECKCLPNYQGDGHYCKPINPCLQAV

PF12947 // ENSGT00760000119025_0_Domain_2 (280, 309)

CHPHARCTYLGPNRHSCTCQE
GYHGDGQVCLPVDHCQTNYGNCSTESTVCIYDGPGQSHCECKEH--YHNYMPGVGCSMAD
VCESKNPCHRNANCSTIAPGQPKCTCQKGYVGDGSTCYGNIMEQLRELNTEPKGKWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 545)

RL
TSFISLLD-KTYAWPLTNLGPFTVLLPT-DKGLKGFNVEDLLVDKKAAQYFVKLHIIAGQ
MSTERMNN--TDTFYTLTGKSGEIFNGDKDNQIKLKLSGGKKKVKIIQGDIVASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 570)

MDQMAPTFESNTEQTIMTMLQL--K

PF02469 // ENSGT00760000119025_0_Domain_5 (570, 700)

YSKFRSLLE----ETNVGRVLEEDGAGTPYT
IFVPSNEALDNMKDGTLDYLLSPEGSRKLLELVRYHIIPLTQLEVATLILAPHIRSLANQ
FIQFNTTSNGQILANDVAVEDTEVIAQNGRIYTLSGVLVPPSI--MPILPHRCDESKREM
KLGTCVSCSL-VYWSKCPANAEPTALFTHRCVYTSRVRSL---KTGCARYCNTTVQIPRC
CQGFYGPDCT-PCPGGFSNPCSGNGQCADGLNGNGTCLCQAGFRGSQCQFCSDP-NKFGP
RCDQKCLCLLGTCDSRIDSDGACLAGTCRGGSAGRFCHKHTSACGPDA-QSCHIHATCEY
NNG---------------------------------------------------TARLSA
PACPRD--------------KR-SDVRQERAECVRTGTGTHTCVCQQGWTGDGRDCWAID
NCLLP

PF12947 // ENSGT00760000119025_0_Domain_9 (1026, 1062)

GTGGCHINATCLYVGPG---QNECECKEGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEAVTS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGQCHPL--
------------------ATCQLMSSGLWSCVCPEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1142)

CYGNAAVELSFLSAAA
P

PF02469 // ENSGT00760000119025_0_Domain_11 (1142, 1261)

FNQWINDASLQPLLSAAANLTVLVPSQQAIADMDHDEKTFWLSKSHMPALVKYHMLRGT
YGLADLQALSPLDRLATALPGSFLHVAKADGNITIEGAAIIDGDNAATNGVIHVISKVLI

ENSGT00760000119025_0_Linker_11_12 (1261, 1280)

PRRSLTGPLPSLLARLDQM

PF02469 // ENSGT00760000119025_0_Domain_12 (1280, 1401)

PDYSTFRASIT----QHSLAGAIEAAGAYTVFAPSNRAVEK
YLQERKAATLEEDVLRYHVVLEEKLLRNDLHSGMHRETMLGFPYLLGFFLQDGQLYVNEA
PINYTNAATDKGVIHGLGKVLEIQKNRCVSNDTTI-VRGKCGKCFQ--QPICPAGTKPLG
KE-IKRCIYTIYFMGKRSLFIGCQAKCVKTIITRECCAGFYGPQCQPCPGEAG-NVCFGN
GICLDGVNGTGACECGPGFAGTACETCTPGAYGAHCDQ--VCSCVHGRCSQGPSGDGSCD
CDAGWRGVKCDTEVTEDDCRGTCHTSANCLLNANGTASCRCAAGFQGNGTVCT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CETSNGGCSSEADCRRTTPGGRRCVCRAGYTGDGVV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCHRNAECTQT
GPNQAVCNCLPKYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINT

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAVCNHTGREERTCTCKPNYIGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1760)

CRGNIYQELPKNPKTSQY

PF02469 // ENSGT00760000119025_0_Domain_17 (1760, 1876)

FFQLLEHSVRDLSGPGPFTVFAPLSTAFDEEPRVRD--WDR
QGLMPQVLRYHVVACQQLLLENLRLTPNATSLQGERIVISVS-QDTVYINNQARIVASDL
INTNGIIHIIDRLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLVTPKDASGRVLQNLTTVAVNHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2039)

-YTKFSSLLQD--LGLL
GIITDPIHTPVTLFWPSDRALEALPPEQQDFLFNQDN--KDKLKEYLKFHVIRDSKILAA
ELPRATAWKTLQGSELSVKCGAGG-DIGDLFLNDQPCRIVQRELLFDAGVAYGIDCLLVS
ATLGGRCDTFATYNFSGDCWSCANTPS-CPRWSKPKGVKQKCRYN-L-SFRGSLDGCREQ
CTMVIRL-PRCCKGYYGRDCQACPGGAEAPCNNRGVCLDQYSGIGQCRCNTGFNGTACEL
CLPRRFGPD-CQPCRCSDHGQCDDGPTGSGRCFCEAGWTGRFCDT---------------
-----------------QTAVPPACMPPCSAHATCRENNTCECNLNYEGDGITCTAVNF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
RQNNGGCATVAQCSQKGTEVSCSCQKGYRGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCRMTGP
GKHKCECKSHYVGDGMD

ENSGT00760000119025_0_Linker_25_26 (2358, 2394)

CEPEQLPLDRCLQDNGQCHAD--ANCADLHFQDATV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLRS
PLGQYKLTFDKAREACANEAASMATYNQLSYAQKARYHLCS-AGWLESGRVAYPTAYASQ
NCGSGVVGIIDYGQRNNKSETWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2584)

YRMK--DVNCTCKAGYVGDGFSCSGNLLQVLTSF
PSLTNFLM-------TRVLRRSPGRPRGHHWHPEQL-KLPVRSRVGTGSSQKKGPNKSLS
GRD

PF02469 // ENSGT00760000119025_0_Domain_27 (2584, 2664)

IEHHLANISMFFYNDLVNGTV----LQTKLGSQLLITSRRDQQQP-------ETRFV
DGRAILQWDVFASNGIIHVISRPLKAPPTPLPPAHA-AGTGIVFATILVLGAAASAAYSY
FRLNRR-RAGFQHFESEE-DIDVSALGSQRPENIPN-PLYESTA-PTAP----EPSCDRC
MDAEGQ---QQDSR--DPLGAL-----

--------TMLQ-I-LILLFLGLAAQNLCSLPETAEQ-AKRCDKKSRLTIRTECRSCSFN
FGMKCPDGYTKITNGTIGIRDCR-YTFEVRTYSLSLPGCRHVCRKDYLQPQCCPGHWGPD
CM-----------------ECPGGARAPCSGRGSCADGM-EGNGSCSCQEGFGGTACETC
TDDNVFGPSCSAMCSCVHGVCNS

PF04863 // ENSGT00760000119025_0_Domain_1 (204, 233)

GIRGDGTCECYSGYTGPNCDKPIP----E

ENSGT00760000119025_0_Linker_1_2 (233, 275)

CAALLCPE
NSRCSPSSEDETKLECKCIPSYKGDGRHCEPINP

PF00008 // ENSGT00760000119025_0_Domain_2 (275, 309)

CSQNICHPHARCTYLGPNQHSCTCHE
GYHGDGQVCLPVDPCQVNFGNCPTESTVCRYDGPGQAHCECAEH--YRNFVPGVGCSVTD
VCESKNPCHRDANCTTIAPGLTKCTCRKGYVGDGSTCYGNIMERLRELNTEPRGEWQG

PF02469 // ENSGT00760000119025_0_Domain_4 (419, 547)

RL
TSFISLLD-KAYAWPLSNLGPFTVLLPT-DKGLKGFNVKELLLNNEAAQYFVKLHIIAGQ
MSTEQMNN--TDTFYTLTGKSGEVFSDDKDRHLKLKLYGGKKKVKIIQGNIIASNGLLHI
LDRAMD

ENSGT00760000119025_0_Linker_4_5 (547, 569)

KVAPTFESNTEQTIMTMLQP--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 670)

RYSKFRSLLE----ETSVGHVLDEDGIGEPYT
VFVPSDEALNSMKDGTLDYLLSSEGSRKLLELVRYHVVPFTQLEVAALISTPHVRSMANQ
IIRFNTTNN

ENSGT00760000119025_0_Linker_5_6 (670, 793)

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX
XXGTCVSCSL-VYWSKCPADSEPTTLFIRKCVYTGRVRSL---KNGCARYCNATVKVPKC
CHGFYGPDCN-Q

PF00008 // ENSGT00760000119025_0_Domain_6 (793, 828)

CPGGFSNPCSGNGQCADGLDGNGTCVCQDGFQGSQCQFCSDP-NKYGP
RCDKRCLCSFGTCDNRIDGDGACLPGTCRDGSAGRFCHKQTSACGPYL-QFCHIHATCEY
SNG---------------------------------------------------TASCVC
KAGYEGDGSL-CSEMDP

PF00008 // ENSGT00760000119025_0_Domain_8 (978, 1016)

CSGLT-RGGCSRNAECIRTGRGTHVCVCHQGWTGDGRD

ENSGT00760000119025_0_Linker_8_9 (1016, 1022)

CSEIN
T

PF00008 // ENSGT00760000119025_0_Domain_9 (1022, 1062)

CLLPSAGSCHHNATCLYVGPG---QNECECKKGFRGNGID

ENSGT00760000119025_0_Linker_9_10 (1062, 1068)

CEPVTS

PF00008 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGKCHPL--
------------------ATCQFTSSDVWSCVCQEGYE-GDGLL

ENSGT00760000119025_0_Linker_10_11 (1125, 1138)

CYGNAAVELSFLS

PF02469 // ENSGT00760000119025_0_Domain_11 (1138, 1261)

AAA
IFNQWINNASLQPMLSAASNLTILVPSQQAIEDMDQDEKAFWLTKSNIPTLIKYHTLLGT
YGVADLQALSPSDMLATSVQGSFLHLAKADGNITIEGASVIDGDNAATNGVIHVINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PQRGLTGSLPNLLTRLDQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1403)

DYSIFRGYII----QHNLASSIEAADTYTVFAPNNDAIES
YIREKKVTTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLYVNEA
PINYTNVATDKGVIHGLGKVLE

ENSGT00760000119025_0_Linker_12_13 (1403, 1485)

IQKNRCDINDTTI-LRGKCGKCPQ--QPICPFGTKPLG
AE-TKRCLYTIYFMGKRSLFIGCQPKCVKTVTTRECCAGYFGPQ

PF00053 // ENSGT00760000119025_0_Domain_13 (1485, 1542)

CQPCPGKAE-NVCFGN
GICLDGVNGTGTCVCGEGFSGTACETCMEGKYGIHCDQ--A

ENSGT00760000119025_0_Linker_13_14 (1542, 1622)

CTCVHGRCSQGPAGDGSCD
CDVGWRGVKCDDEITKDECNGTCHTSANCLLSPDVAASCKCAAGFQGNGTVCT----AIN
A

PF00008 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEISNGGCSRRAVCKRTTPGSRACVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CIEINP

PF00008 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENHGGCHQHAECTQT
GPNQAACNCLSKYTGDGKVCTLINVCLTKNGGCSEFAVCNHTGEDERTCTCKPNYIGDGL
TCRGNIHQELPKNP

PF02469 // ENSGT00760000119025_0_Domain_17 (1755, 1876)

KTSQYYFQLLEHSVRDLVGPGPFTVLAPLSAAFDEEPQIKD--WDK
QGLMPQVLRYHVIACHQLLLENLKLTPNATSLQGESIVISVS-QDTVLINNKAKIISSDI
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1904)

PQNLLVTPKDASGRILQNLTTVAINHG-

PF02469 // ENSGT00760000119025_0_Domain_18 (1904, 2040)

-YIKFSNLIQD--SGLL
SVITDPIHTPVTLFWPSDQALQALPPEQQDFLFNQDN--KDKLKEYLKFHVIRDSKVLAV
DLPRSATWKTLQGSELSVKCGAGS-DIGELFLNGQMCRIVQRELLFDLGVAYGIDCLLI

ENSGT00760000119025_0_Linker_18_20 (2040, 2123)

D
PTLGGHCDTFTTFDVSGNCGSCVHTPS-CPRWTKPKGEKRKCLYD-L-PFRRNLEGCKQQ
CTLVIQL-PKCCKGYFWPDCQA

PF07974 // ENSGT00760000119025_0_Domain_20 (2123, 2158)

CPGGPDTPCNNRGVCLDQYSPAGQCKCNTGFNGTA

ENSGT00760000119025_0_Linker_20_21 (2158, 2171)

CEL
CWPGRFGPD-

PF00008 // ENSGT00760000119025_0_Domain_21 (2171, 2203)

CQPCGCSDHGQCHDGITGSGQCVCETGWTGRFCDT---------------
-----------------QTVLPLVCMPPCSAHATCKENNTCECNLNYEGDGITCTVVDF

PF00008 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQNNGGCAKVAKCSQKGTKVSCSCQKGYQGDGHS

ENSGT00760000119025_0_Linker_24_25 (2315, 2321)

CTEIDP

PF00008 // ENSGT00760000119025_0_Domain_25 (2321, 2358)

CADGLNGGCHEHATCQMTGP
GKHKCECKRHYVGDGLD

ENSGT00760000119025_0_Linker_25_26 (2358, 2393)

CELEQLPIDRCLQDNGQCHAD--ADCADLHFQDTT

PF00193 // ENSGT00760000119025_0_Domain_26 (2393, 2487)

AGVFHLRS
PLGQYKLTFDKAREACTKEAATMATYNQLSYAQKAKYHLCS-AGWLDSGRVAYPTSYSSQ
NCGSGIIGIVDYGTRNNKSEMWDVFCYRMK--DVNCTCKAGYVGDGFLCSGNLLQVLMSF
PSLTNFL--------TEVLAYSNSSARGRAF-LKHLTDLSIRSTLFVPQNSGLGENETLS
GRDIEHHLTNVSVFFYNDLVNGTV----LHTRLGSQLLITSSQDQRQ-------LETRFV
DGRAILQWDIFASNGIIHVISRPLKAPPTPVTSSHAGLGTGMFFAIILVIGAIALAAYSY
FRLNRR-TIGFQHFEXXX-XXXXXXXXXXXXXXXXX-XXXXXXX-XXXX----XXXXXXX
XDPEDQ---QLDSI--DPLGAL-----

--------IMLQ-Y-LVIFCLGFVVQNFCFSAETAGQ-TRRCDQKSLLTIRTLCQPCSFN
FAVNCPDGYTKITNGTEGIPDCS-YTIEAYIHTLHLPGCRHICRKDYLQPRCCPGHWGQD
CT-----------------ECPGGAGSPCNGRGSCAEGM-EGNGTCSCQEGFGGTACETC
ANDNLFGPNCSAVCNCVHGVCNSGLDGDGTCECHSAYTGPTCDKFIP----ECSALLCPE
NSRCSPSSEDETKVECKCLPNYQG--KSCEPINPCLQK

PF12947 // ENSGT00760000119025_0_Domain_2 (279, 309)

ICHPHAHCTYLGPNRHSCACQD
GYHGDGQVCLPVDPCQRNFGNCPTNSTVCKYDGPGQSHCECKEY--YHNFVPGVGCSMIN
ICESNNPCHKNANCITIAPGQIKCTCQKGYVSDGFKCYGNIMERLRELNTEPRGKWQGKL
I

PF02469 // ENSGT00760000119025_0_Domain_4 (422, 545)

SFISILE-KAYAWPLSNLGPFTVLLPT-DNGLKEFSANELLVDDKAARYFVKLHIIAGQ
MSTKYMNN--TDTFYTLTGRSGEIFNSDKDNQINLKLYGGKKKVKIIQGDLIASNGLLHI
LDRA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNLEPTFESNNEQTIMTMLQT--

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSKFRSLLE----ETNVGHALDEEGGGGPYT
IFVPSNEALNNMKDGTLDYLRSPEGSRKLLELVRYHIVPFTQLEVATLISTPHVRSMANQ
LIQFNATDNGQILANNVAMEEIEITAKNGRIYTLNGVLIPPSI--VPILPHRCDETKSGI
KQGTCVSCVL-MDGSRCPANTEPTKFITHRCVYSRKFRNL---KYGCARYCNGTVKIPKC
CKGFYGPDCN-QCPGGFSNPCSGNGQCSDGLGGSGMCICQEGFQGSQCQFCSDP-NKYGP
RCSKKCLCVHGTCDSRIDSDGACLTGTCRDGSAGRLCDKQSSACGPYI-QFCHIHATCEY
SNG---------------------------------------------------TASCIC
KAGYEGDGTV-CSETDPCTGPT-PGGCSRNAECIRTGTGTHTCVCQPGWTGNGRDCVEIN
NCLLPSAGGCHHNATCLYVGPG---QNECECKKGFRGNGIDCEPIAS

PF12947 // ENSGT00760000119025_0_Domain_10 (1068, 1125)

CLEQTGTCHPL--
------------------ANCQVTNSGVWSCVCQEGYE-GDGFL

ENSGT00760000119025_0_Linker_10_11 (1125, 1140)

CYGDAAVELSFLSEA

PF02469 // ENSGT00760000119025_0_Domain_11 (1140, 1261)

A
VFNQWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPSLIKYHILLGT
YRVADLQTLSSSDMLATSLPGNFLHLAKMDGNITIEGASIVDGDNAATNGVIHIINKVLV

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PKRALLGSLPNLLTRLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----HYNLANAIEAANAYTVFAPNNNAIEN
YIREKKALSLEKDVLRYHVVLEEKLLKNDLHNGMHRETMLGVSYLLGFFLRNDQIYVNEA
PINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTTI-VRGTCTTCSA--KQLCPFGAKRLD
NE-IKRCIYTIYFMGKRALFIGCQPVCVKTVITRECCAGFFGPQCQACPGNTQ-NVCSGN
GICLDGVNGTGVCECGDGFKGTACETCTEGKYGIRCDQ--ACSCVHGRCNQGPLGDGSCD
CDVGWRGVHCDEVIKKDDCNGTCHTSANCIL-TDGTPSCKCAAGFQGNGTICT----AIN
A

PF12947 // ENSGT00760000119025_0_Domain_14 (1622, 1658)

CEIINGGCSAKADCQRTTPGRRVCVCKAGYTGDGIV

ENSGT00760000119025_0_Linker_14_15 (1658, 1664)

CLEINP

PF12947 // ENSGT00760000119025_0_Domain_15 (1664, 1700)

CLENNGGCDKNAECTQT
GPNQAACNCLPAYTGDGKV

ENSGT00760000119025_0_Linker_15_16 (1700, 1706)

CTLINV

PF12947 // ENSGT00760000119025_0_Domain_16 (1706, 1742)

CLTKNGGCSEFAICTHTEQEGRTCTCKPNYLGDGF
T

ENSGT00760000119025_0_Linker_16_17 (1742, 1757)

CRGSIYQELPKNPKT

PF02469 // ENSGT00760000119025_0_Domain_17 (1757, 1876)

SQFFFQLQEHSVKDLVNPGPFTVFAPLSTAFDEEARVID--WDK
QGLMPQVLRYHVIACHQLLLENLKLISNATSLQGEPVVISVS-QGAVYLNNKAKIISSDI
ISTNGIIHIIDKLLS

ENSGT00760000119025_0_Linker_17_18 (1876, 1906)

PQNLLITPKDTSGRILQNLTTLATNNG--Y

PF02469 // ENSGT00760000119025_0_Domain_18 (1906, 2039)

IKFSKLIQD--SGLL
SVITDPVHTPVTLFWPTDQALQALPAEQQDFLFNQDN--KDQLRQCLKFHVIRDAKVLAV
DLPRSPGRKTLQGSELSVKCGTGN-DIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLMD
TILSGRCDTLTTFNISGDCGSCFNTPS-CPKWSKPKGVKQKCLYN-L-SFRRNLEGCQEQ
CGLFVQI-SKCCKGYFGRDCQACPGGAEAPCNNRGVCQDQYWGTGECKCNTGFNGTACEM
CLPGRFGPD-CLPCRCSDHGQCDDGITGSGQCFCETGWTGPLCDT---------------
-----------------QAVLPVVCTPPCSVHATCKENNTCECNLDYEGDGITCTVVDF

PF12947 // ENSGT00760000119025_0_Domain_24 (2280, 2315)

C
KQDNGGCAKVAKCSQTGTKVSCSCQKGYKGDGRS

ENSGT00760000119025_0_Linker_24_25 (2315, 2326)

CTEIDPCADGL

PF12947 // ENSGT00760000119025_0_Domain_25 (2326, 2358)

NGGCHEHATCKMTGP
GKHKCQCKSHYVGDGLN

ENSGT00760000119025_0_Linker_25_26 (2358, 2395)

CEPEQLPIDRCLQDNGQCHAD--ANCVDLHFQDTTVG

PF00193 // ENSGT00760000119025_0_Domain_26 (2395, 2487)

VFHLRS
PLGQYKLTFDKAREACANESATMATYSQLSYAQKAKYHLCS-AGWLESGQVAYPTAFASQ
NCGSGVVGIVDYGPRPNKSEMWDVFC

ENSGT00760000119025_0_Linker_26_27 (2487, 2564)

YRMK--DVNCTCKVGYVGDGFSCSGNLLQVLMSL
PSLTNFL--------MKVLTYSNSSARGHTF-LQHLTDLSFRG

PF02469 // ENSGT00760000119025_0_Domain_27 (2564, 2664)

TLFVPQNSGLGENETLS
GRDIEHHLASVSMFFYNDLVNGTT----LQTRLGSKLLITTGQDPSQQ------MEARFV
DGRAIVQWDIFASNGIIHVISRPLKAPPAPVTSTHTGLGAGIFFAIILVIGAVALAAYSY
FRLNRR-TIGFQHFESEE-DINVAALGKQQPESISN-PMYESTA-SAPP----EPSYDPF
TDSDER---QLEGS--DPLGTL-----

------------------------------------------------------------
------------------------------------------------------------
--------------------CPGGAASPCNGRGRCSQGI-AGNGTCTCQKGFGGTACEKC
AEDNLFGPDCTSVCDCVHGVCNSGIAGDGSCTCLSGYKGLRCDEPIA----ECAALRCPA
NSRCAASAEDGTQLQCTCLPSFHGDSTRCEPINPCSRKVCDPNADCIYLGPNQHKCTCGE
GYTGDGQICLPIDPCQAAHGSCPAHSSICIYDGPGKSHCECKEH--YTNFVPGKGCSMMD
NCETNNTCHKKAKCLTVAPGQIACTCQEGSVGNGFVCYGNIMERLQDLNAEVGGQWQGKL
TSS

PF02469 // ENSGT00760000119025_0_Domain_4 (424, 545)

LLLME-NSYEWQLSTLGPFTVLVPT-NKGLKGTNVKDLLKNKQKAQYFVKLHIIAGQ
LNTSSLNN--ANVIYTLTGKSGEISKGEKDNQLRIRIQGGRGKGKILQGDIIASNGILHI
IDKA

ENSGT00760000119025_0_Linker_4_5 (545, 569)

MDNMEPTFESSNEKTIMSVLQANR

PF02469 // ENSGT00760000119025_0_Domain_5 (569, 700)

RYSQFASLIE----KTGLGMDLQQ--DNQPYT
VFVPSNKALSNMKAEVLDYLLSAKGSWKLLELVRYHIVSNTELEVASLVSIEHIRTMAKQ
FIHFNRSSTGQILVSGEKMEETDIVAKNGRIYILEGVLIPPTI--VPILPHWCEETS-QR
SSGIGTSAL--------------------------------------------CYTNAFC
CKGFFGPNCR-PCPGGFSKPCSGNGQCMDGLDGNGTCVCSEAFQGLSCQLCSDP-GKYGP
QCDKECLCIYGKCDNRIDSDGTCLPGSCRAGYTGSLCEQQIVPCEASL-QLCHADADCQL
SDG---------------------------------------------------TVSCVC
KPGYEGDGLS-CSKVDPCAVLN-PGGCNINAECVQTGPGEHRCVCQAGWTGDGRDCSAIN
NCLLPSTARCHENATCIYIGPA---QNDCKCKDGFQGNGIECTPINSCLEQNGKCHHL--
------------------ATCQFVSSRGWECVCPEGYE-GDGRTCYGNAADELSTLSEAA

PF02469 // ENSGT00760000119025_0_Domain_11 (1141, 1261)

AFNQWVNEAKINSVLSTTSNLTVLVPSLQAIENMDEDEKAFWMSKSNIPTLLKYHVLTGA
YSFADFQNLSSSDMLPTSLQSKFLHLSKENGNLTLEGAHFVASDIASTNGVIHVIDKVLT

ENSGT00760000119025_0_Linker_11_12 (1261, 1281)

PLRS--AVMPRLLARLEQMP

PF02469 // ENSGT00760000119025_0_Domain_12 (1281, 1401)

DYSIFRGYII----QYSLANEIEAANTYTVFAPSNDAIEN
YLKDKKSATLDEGQIRYHIVLDEKLLKNNLHNGMHRETMLGFSYQVGFFLHNSQLYINDA
PISYANVATDRGIIHGLGKVLEIQKNRCDTNSTVI--IEKCRICSQ--PSSCPPGTKEIV
RV-KKYCVLTENHMRQYTIQIGCKPKCAKTIINRECCAGFFGPQCQACPGRAG-SACSGN
GVCLDGINGTGSCQCDRGFEGTACESCSPGRYGRSCDQNIVCTCVHGKCSSGVDGDGSCE
CDVGWRGVTCDTEIKDDACNASCHTSANCLLLSNGTAYCKCAAGFEGNGTFCTG--NSID
ACESSNGGCSSKAECRRTTPGNRACVCSAGYTGDGIVCIEINPCLMNNGGCDRNAECTQT
GPNQAVCNCLKGYSGDGKTCTYISLCSQNNGGCSEFAICNDTELTERTCTCKPNYIGDGF
KCRGNIFQELLRNSNTSRFYFHLEALSI

PF02469 // ENSGT00760000119025_0_Domain_17 (1769, 1876)

RDISGPGPFTLFVPHTDVLNSDPRVKD--WVA
KGVMAQVLRYHVVGCASLLYKDLAAITNVTSLQGDLIHISYS-QNSLVLNNKAEIVLSDA
VGTNGVIHVINQILV

ENSGT00760000119025_0_Linker_17_18 (1876, 1908)

PSHMQDFPLKKV---CESLKMVAAKHG--YIL

PF02469 // ENSGT00760000119025_0_Domain_18 (1908, 2038)

FNTLLEK--NNLL
GLINDPIHKPVTLFWPTDTAIRGLPQEQQDFLFKKSN--TNKLVQYLKFHIVRDAAVLAY
QLQSSTSLKTLQGSNLSVSCGDNG-EIGALFLNDGQCKVVQRQLEFDGGIAYGINCLLTE
PSLGGRCDSFLTMEFMGHCASCFNNYK-CPPGTKPKEGMQWCTYE---SYGLRRDGCRRN
CSMVIHI-AKCCKGYFGPDCQACPGGPETPCNGHGSCDDGYTGTGECRCTGGFNGTSCEL
CLPGRYGFT-CRPCECKNNGQCDEGYSGTGRCFCETGWTGRLCET---------------
-----------------KLALPPVCSPSCSANAVCTENNTCQCKPLYDGDGITCTAAELC
KQNNGGCHKAADCTQHGVKVFCSCQKGYKGDGFTCLPINPCADGFNGGCHEHAICTVTGP
GRRKCECKINYIGDGLNCSVMQLPLDRCLQDNGQCHPD--ADCADLHFQDTTV

PF00193 // ENSGT00760000119025_0_Domain_26 (2394, 2487)

GVFHLQS
PVGQYRMSYEQAKEACANESATIATYDQLLYAQKARYQLCS-AGWLDGGRVGYPTAFSSP
NCGSGHVGIVDYGRRVNLSETWDTFCYREK--EVNCTCKPGYVGDGISCSGNLLQVLMSF
PTLTNFL--------SDIMAYSNTSRKGREF-LQYLTDLSVHATLFAPIDSGLKENETLS
GRDIEYHLSNANIMFYEDLTNGTT----LLTRLGKKLLITNTGGQEHRIST--ADQIRYV
DRSAIVEWDIIASNGIIHIISEPLKAPSEPA-PLHASAGTGIFFGICLVTGIVALVGYSY
LRFRKK-NFGFQHFKSKD-DTDTTSLDKSQPSNITN-PSYESSSTLTSP----EPAYDLF
S--------------------------