Query Results 

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----------------------S--EMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFI
RGIEENS-RSRRDGLFHENECIVKINHVDLTDKTFAQAQDIFRQAMKFQSVILEVLPPYN
REQYEKSAIAPLCILNNEEGVT-KTKI-PPPLHPKPAVKTINISGA-ILESGVQGALQQA
KS-PNLPRLGRKPSSPSLSPLMGFGNKRNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSVHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETVCLI

ENSGT00760000119017_2_Linker_1_2 (480, 518)

V
ARQEEAFLPRELKGEPN-CSIFSPETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGADL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQ
LVVLRRLEVHTEERS--DQGVFQKSAFDGSHNFTAA--SRRNDILLQQFVTCSAQEGVKA
-VLLISDRGNGENETPPPL-PPHPSEDLLNEDYNHSPIINSAVHLTD-HINFRSLT-PAK
QSESINLKASKSMDLGKKGWGDTQRSY---SDGDNDSSGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDGE-EDG-SDKSSHCGQEAQ
NVESAPPGNPEIEDAEIKAKKDKKSREKEK---------KKGKSKIKEKKKKEENEDPEK
K-K-KKGFGVMLRFGKKKEDKSGKADQTGAP--KQGVLKEEELEKMKDERQRIGAKHQEL
RQK-QLRGLSDYSAGPG--GPDIDDDE--VDPNY---ARVNHFREAYPPGSIYRPSSPAV
GETFVYLRDSSSAPLEREHLEGLYAKINKQHYPQTSGDSGCTGGGNADRIQRLRQEYQQA
RREGLPFYEDDEGRTQLPDYDQRWVPGKGPDGSSYNLHFEGVERQYASLPRRGPAEPLEY
LT-GPRVTYKERDLPYYHG-GQPVMHPSKGNYIRAPD-TRVAELRYPQYYPAQPIASQHK
GPLRQDVPPSPPQSHRAPAYSEMV--RHRGTSPDQYHYRQQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGKTGIVVPCKDGQIRVKDVTHQALQRYLRTKEKDPSYWVNIHHLEYTDGGILD
PDDILADVVEDKDKLIAVYDEQDSLPKSD--DINGSLTDGNSPDAFETEVAAQLAAFQPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PTLGPPE-FPVGASHANDHVLKTSVSCSAHSSS-
-EDWDPAARSEVLTSQKTKFIFS--DLTRKVEISGEDGPLGIHVVPYFSSLSGRILGLFI
RGIEENS-RSKREALFHENECIVKINSIELADKTFAQAQDLFRQAMKSPNIILEVVPSYN
REQYEKSVITSLYSPDNTEHVS-KAKN-PPPIYPKPMAKEVGLSGLNSLDTGVWTVLHPA
KS-PNIPRVGRKTSSPTLSPLMNFGSKRNAKRIR

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSVHG
PGPIFVKNILPRGAAVKDGRLQSGDRILEVNGRDITGRTQEELVATLRSTKQGDTVSLI

ENSGT00760000119017_2_Linker_1_2 (480, 519)

I
ARQEETFLPRELKGEPF-CNMLSLETTEQLTFEIPLND

PF00595 // ENSGT00760000119017_2_Domain_2 (519, 589)

SGSAGLGVSLKGNKSRETGADL
GIFIKSIIHGGAAYKDGRLRKNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVVLRRLDRQTEVEHIEHVASFSKQDLEGNFNFTSI--PRCSDAAVQCFGAYCQQGRLKE
--LHTSESGMVENEVPPPL-PPHPSDELL-TDYNHSSIADSAAYLPDQHINFRSLT-LAK
QTESINLKASKSMDLVADES--NMSLL---ARQQQEPPGKDVGPTLGLKKSSSLESLQTA
VAEVKKNELPFYRPKPHMVRGRGCNESFRAAIDKSYDGPEDFP-EDGMSDKSSLSGQEVQ
NFHAS----SELEDVEGKAKKYKKTKDKSKMKEKNKKLNLKNKSKMKEKDKKEENEDPER
KTK-KKGLGAMLRFGKKKEDKGVKGDQKGNT--KTGTLKEEEFEKMKEERERIGAKHQEL
RQK-QSRGPAEYPIGPVGPPPDIDDDE--TDPNY---ARVNHFREMYPKTNAYRPSSPPT
PDTFGS--ENPPAPSDRDHLEGLYARINKPLHQHAPVESDRPSAGTAERIQKLRKEYHQA
RREGLPFYDENDSRGRPS--DQHWVSGKIPDGPSHHLQYEGIERQYASLPRHGPVEPAEY
IT-GLRAPYKERDLPYFQG-GQPTGQPSKGSYVHPHDASRPAELWYAQYYSTQPV-SQHK
GPLRQDVPPSPPQGHRVLPYNEMGRVASRPAGPDHYQYRHQDPRQKDPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADAQPSSSHPGGQGLKPVIPDSTQ-NLE
DREVMNGEQTELVTSPRTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMRSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNSDGIL-KTKV-PPPVHGKSGIKTANLTRTDSPETDASASLQQS
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNNEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKLCFENCQNTVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-APHSALELGLEDYNHSSGVDSAVYFPDQHINFRSVT-PAR
EPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDVENKARKIKKAKEKEKKK-------EKGKLKIKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPWDGRPLSPERDHLEGLYAKVNKPYHPLGPVDSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSEYDLLWVSGKGPDGNAHSLRFEGMERQYASLPRGGPTDPVDY
LPAAPRGIYKERELPYYPG--SHPMHPPKGSYPRPAE-LRVADLQYPQHYPPPAA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDRYPYRTQDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDILADVVEDKDKLIAVFDEQEPLCKIE--SPSGNPADRQSPDAFESEVATQLAVFKPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPSTASPSSQSLKPVVQDSIQ-NVE
NREVMNGEQTELLVLPRTKAALS--HMTRTVEISGEGGPLGIHVVPFFSSLSGRVLGLFI
RGIEENS-RCKDEELFQENECIVKINNVELVDKTFAQAQDVFRQAMKSSSVILHVLPPQN
REQYEKSVIGPLNIFDNSDGVL-RTKV-QPPVHGKSGLKTINLSGTNSPEADELTSLQQG
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGKDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CSALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGEALLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEDLA--ECGALSKPCFENCQNALS-TSRRNGSSVLHTFGTYSPKDKQKD
PLL--PSDRWAESEARLSP-PPQSSLELGLEDYNHSSGVDSAVYFPDQHINFRSMT-PAR
QPESINLKASKSMDLVPDES--KVQSL---ADHRSDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEDVE-ADGLSDKSSHSGQGAL
NCESIPQENSELQDVENKARKVKKHKEKEKKK-------EKVKLKVKEKKRKDENEDVER
KMK-RKGFGAMLRFGKKKEEKSGKVEQTGMR--KPQNLAEEELERMKE-RDWIGAKHQEL
REK-QTRGLVDYATGVIGSVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPPR
VGPLSYPRDGRPLSPERDHLEGLYAKVNKPYHPPAPVDSDRPLGGNTDRIQKLRKEYYQA
RREGFPLYEEEDGRMRPSDYDLHWVSGKGPDGTVHNFRFEGMERQYASLPRGGLTDPVDY
LMAAPRGLYKERESPYYPG--AHPVHPPRGNYPRPPD-LRVADLRYSQYYPPPPV-PQHK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPRGGSPDQYPYRNQDPRQKNPMTAAV

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PF12053 // ENSGT00760000119017_2_Domain_0 (75, 147)

LIAVFDEQEPLHKIE--SPSRNPGDPQSPDAFETEVAAQLAAFRPV
G--GEIEVTPSALRVGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PSLGPPADAQPSASHPGGQSLKPVVADSTQ-SLE
DGEIMNGVQTELPVSPKTKDVSS--DMTRTLEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEDNS-RSKREGLFHENECIVKINNVDLADKTFAQAQDVFRKAMKSPSVLLHVLPPQH
REQYEKSFIGPLNIFANSDGAL-RTKV-PPPAHCKSGVKTANLTGTGCSEADTSAPLQQS
KS-PQVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CYALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSQETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRQEKPVEEPA--ECGALSKPCFENCQNAVT-TSRRNDNSPLQPFGTYSPQDKQKD
LLL--PHDGWTESEVPPSP-PPHPALELGLEDYSHSCGVYSSGYLPDQHINFRSVT-PAG
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPCNDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDDPEELE-ADGLSDKSSHSGQGAL
NCESPPQGISELEDLENKARKVKKTKEKEKKK-------DKGKLKVKEKKRKEENEDPER
KIK-RKGFGAMLRFGKKKDDKGGKAAQKGPL--KLGGLKEEELEKMKEEQERLGAKHQEL
REK-QARGLIDYATGAMGSVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPPR
AGPLGYPRDGRPLSPERDHLEGLYAKVNKPYHPAAPVDSGRPMGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSDYDLHWVPGKGPEGNAHSLRFDGMERQYASLPRGGPADPVDY
LTAAPRGLYKERELPYYPG--AHPMHPPKGSYPCAPD-LRVADL----------------
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PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKEGQLRVRELTQQALQRYLKTQEKDPSYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKVDNSKKCSSWSYKIC-KTKMFLHSENQNSDAFQTEVEGRR--RKAI
G--TAVTSALFLCPAGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PVPSPPADAQPSTSHPGGQSVKPVVPDSTQ-NLE
DREVMNGVQTELQTSPKPKDTLS--DMTRTVEISGEAGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVVLHVLPPQN
REQYEKSVIGPLNIFGNSDGVL-KTKM-PLHVHGKSGGKTVNLAGTNSPEADASTSLTQN
KS-PRVPRLGRKLSSPPLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 519)

I
ARQEGNFLPRELKGEPD-CYALSLETTEQLTFEIPLND

PF00595 // ENSGT00760000119017_2_Domain_2 (519, 590)

SGSAGLGVSLKGNKSRETRTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPTEEPA--ECGAFSKPCFENCQNSVT-TSRRNDNSTLHPLGTYSPQDKQKD
LVL--PTDGWAESEGPPSP--PHPGLELGLEDYSHSSGVDSAVFFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---ARHESESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGHGAL
NCESAPQGNPELEDTENKARKVKKTKEKEKKK-------EKGKLKVKEKKHKEDNEDPER
KMK-RRGFGAMLRFGKKKEDKGEKSEQKVTP--KRGGLREEELEKMKEERERIGAKHQEL
REKQ-ARGLVDYAAGAFGSVHDMDDDE--MDPNY---ARVNHFREPCVSASVFRSPSPPR
AGPFGFPRDGRPLSPERDHLEGLYAKVNKPYHPPAPVDSVRPPSGSTDRIQKLRKEYYQA
RREGFASYEDDEGRARQSDYDFLWVSGKGPDGNAHNFHSEGLERQYASLPRGGPADPADY
LTAAPRGLYKERELPYYTG--AHPLHPPRGSY-----------LRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQRHRVPVYPDMGRPGPRGGSPDRYPYRTQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAVFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADAQPSTSHPGGQGLKPVIPDSTQ-NLE
DREVMNGEQTELVTSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINDVDLVDKTFARAQDVFRQAMRSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNSDGIL-KTKV-PPPVHGNSGIKTANLTRTDSPETDASASLQQS
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSAIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRVLKGEPD-CCALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNNEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPAEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-APHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
EPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
KCESAPQGSLELEDVENKARKVKKAKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARCLLDYATGAIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKSYHPRGPVDSGRPTGGSTDRIQKLRKEYYQA
RREGFSLYEEDEGRARPSDYDLLWVPGKGPDGNAHSLHFEGMERQYASLPRGGPTDPVDY
LPAAPRGIYKERELPYYPG--SHPMHPPKGSYPRPAE-LRVADLQYPQHYPPPTA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDRYPYRTQDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKTE--SPGGNPADRQSPDAFETEVAAQLAAFKPV
GGGGEIVVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSTASLSGQSLKPVVLDSAQ-NVE
NKEAMNGEQAGLLSLHRPKDELS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQN
REQYEKSVIGPLNIFGNNDGAS-RTKA-PPPARGKPGLKAVHLTRASSPEGEEPASPQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLESSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEELS--ECGALSRPGFENCQEALS-TSRRNDSSILYPFGTYSPQDKRKD
LLL--PSDGWAENEVPPSP-PPHPALEWGLEDFSHSSGVDSAGYFPDQHVNFRMVT-PVR
QPELINLKASKSMDLVPDEG--KVQSL---ADRRSDSPGKDFGPTLGLKKSSSLESLQTA
VAEVKKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAD-ADGLSDKSSRSGHTAL
NCESAPQGNPELDNVENKAKNIKKTKEKEKKK-------GKGKLKVKDKKLKEEHEDAER
KMK-RKGFGAMLRFGKKKDDKVGKAEHKGAQ--KSGHSEEEEQERMKEERERIGAKHQEL
REK-QARGLVDYATAVTGPVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPLR
AGPLAYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPLVGTTDRIQKLRKEYYQA
RREGFLLYEDENTRARPSDHDLRWVSGKGPDGSAHNLHFEGMERQYASLPRGGSADPVDY
LTASPRGRYNDRELPYYPG--PHPVHAPRGSYPRPPD-LRATDLRYPQYYPPPPA-HQHK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PVPGPPADTQPGASHPGGQSLKPVVSDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGVEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-PPPVHGKSGLKAANLSGAESPETDASTCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKVKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSDYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADAVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-SQHK
GPFRQDVPPSPPQHQRMPAYQETGRPAPRGGSPDQYPYRTQDSRQKNPMTAAV

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----MNGVQTELLTSPKTKDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPPN
REQYEKSVIGPLNIFGNNDGVL-RTKM-PPPVHGRSGIKTVHLTGAGSPGEDASTSIPQS
RS-PRVPRGGRNASSPSLSPLLGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGAFLPRELKGEPD-CYALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHDAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEEPA--ECGAFSKPCFENSQNAIP-TSRRNENSALHPFGMYSPQDRQKG
PSL--PGDGWAESQVPPSP-SPHPVLELGLEDYSHSAGVDSAVGFPDQHINFRLVT-PAR
QPESLNLKASKSMDLVPDES--KVHSL---AGHRSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEESE-ADGLSDKSSHSGQGAV
NCDSAPQGHSEIEDVENKARKVKKPKEKEKKK-------EKGKLKVKEKKQKEDSEDPDR
KMK-RKGLGAMLRFGKKKEDKGGKAEQKNPPQRKHGGLRDEELDTMREERARIGAKHQEL
REK-QARSLVDYATGAIGSLHDMDDDE--MDPNY---ARVNHFREPCASATVYRSPSPPR
TGPLGYPRDGRPLSPERDHLEGLYAKVNKPYQPPMPVDSGRPASGSADRIQKLRKEYYQA
RREGFASYEEDDGRARPSDYDLHWVSGMGPDGSAHNLRFEGMERQYASLPRGGPADPVDY
LTAAPRGLYKERELPYYPG--AHPVHPPKGSYPRPPD-LRVTDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRVPAYPEMGRPGPHGGSPDQYPYRTQDPRQKDPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLHKFE--SPSGNPEDWQSPDAIETEVAAQLAKFKPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPSSSHPSGQSLKPVVSDSTQ-NLE
DREVMNGVQTELLTSPKIKGALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPDVLLHVLPPQN
REQYEKSVIGPLNIFSSNDGVL-RTKA-PPPVHGKSGVKTVNLTGTNSPEADASPSLQQN
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CYALSLESSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPA--ECGAFSKPCFENCQNTLS-TSRRND-TILHQFGTYSPQDKQKD
LLL--SNDGWAESEVPPSP-PPHSGLELGLEDYSHSSGVDSTVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHRSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDAENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-RKGFGAMLRFGKKKEDKGGKADQKGTL--KPGNLREEELERMKEERERIGAKHQEL
REKQ-ARDLVDYATGAAGSAHDMEDDE--MDPNY---ARVNHFREPCASASVFRSPSPPR
PGPLGYPRDGRPLSPERDHLEGLYAKVNKPYHPPAPVDSGRPMGGSTDRIQKLRKEYYQA
RREGFPLYEDEEGRARPSDYDLHWVSGKGPDGNAHNLRFEGLERQYASLPRGGPADPADY
LTAAPRGLYKERELPYYPG--LHPGHPPKGSYSRPPD-LRVADLRYPHYYAPPPA-PQHK
GPFRQDVPPSPPQHQRVPAYQEMGRVGPRGGSPDQYPYRTQDPRQKNPMTAAV

MKVTVCFGRTGIVVPCKEGQLRVRELTQQALQRYLKTREKDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDRXXXXXXXXXXXXXXX-XXXX--XXXXXXXXXXXXXXXAALAVFK--
-PGGEIEVTPSALKLGTPLLVRRSSDPVPGLPADTQPTASHPGGQSLKPVVSDSTH-NLE
DREVMNGVQTELLTSPKTKDGLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQDVFRQAMKSPSVFLSVLPPQN
REQYEKSVIGPLNIFGNNDGIL-KTKV-PPPVHGKSGLKTMNLTGTNSPEADASTSLQQS
KS-PRVPRAGRKPSSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGSFLPRELKGEPD-CYALSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDL
GIFIKSVIHGGAAFKDGRLRVNDQLIAVNGESLLGKSNHEAMETLRRSKSKEGNIRGMIQ
LVILRRPERPTEEPV--ECGAFSKPSFENCQNAVT-ASKRNDNSTLPLFGTYSPQDKQKD
LLL--PSDG-AESEVPPSP-PPHSGLELGLEDYSHSSGVESTIYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKLESPSNDLGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEFE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDVENKARKAKKNKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-RKGLGAMLRFAKKKDDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLVDYATGAIGSVHDMDDDE--MDPNY---ARVNHFRXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGRPMGGSTDRIQKLRKEYYQA
RREGFPLYEDEEGRARPSDYELHWVSGKGPDGNAHNLRFEGMERQYASLPRGGPADPIDY
LTAAP-GLYKKREL----------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPGASHPGGQSLKPVVSDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGVEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-PPPVHGKSGLKTANLTGAESPETDASTCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTVGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSDYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADAVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-SQHK
GPFRQDVPPSPPQHQRMPAYQETGRPAPRGGSPDQYPYRTQDSRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MNGVQTELFTAPRTKDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKREGLFQENECIVKINSVELVDKTFAQAQDVFRQAMKSPHVLLQVLSPQN
REHYEKSVIGPLHIFGNSDGVL-RTKV-SPPVHGKSGLKTANLTGANGPEADPATSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLDTSEPLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKARETGLDL
GIFIKSIIHGGAAFKDGRLRVNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPTEETA--ECGAFSKPCFENCQNVLP-ASSRNESGILHSFDNYSPQDKQKE
LVL--PHDEWARGEAPPSL-PPHPGLEMGLEDYSHSSGVDSAVYFPDQHINFRSMT-LAR
QPESINLKASKSMDLVPDES--KVHSL---AGPRPESPNRDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPWPHMVRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSHSGQGAL
NCESAAQGNSELQDLENKARKVKKTKEKEKKK-------EKGKLKVKEKKQKENNEDPER
KIK-RKGLGAMLRFGKKKDGKRGEAEQKGG-P-KPGSPRPEEPEPREAERARIGAKHQEL
REK-QARGLLDYATGTIGSVHDMDDDE--IDPNY---ARVNHFREPCASANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYQPPVPVDSGHPAGGSSDRIQKLRKEYYQA
RREGFLLYEDDEGRPRPSEYELHWVSGKSPDGNAHNLRFEGMERQYASLPRAGPADPVDY
LTAAPRGLYQERELPYYPG--AHPVHPPKGGYARPPE-LRMTDPRYPQYYPPPPV-PQHK
GPFRQDVPPSPPRHQRMPAYQEMGRAGPRGVSPDRHPYRTQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLQVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKIE--SPSGNPVDRQSPDAFETEVAAQLAAFKPV
G--GEIVVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSTASPSGQSLKPVVPDSTQ-NLE
NREVMNGEQTELLTSHRTKDALS--DMTRMVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQN
REQYEKSVIGPLNIFGNSDGAS-RTKV-PPPTRGKPGLKAVNLAGTNSPEADESTSPQQS
KS-PRVPRLGRKASSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVVMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQDGSFLPRELKGEPD-CYALSLETSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRTNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRLERPLEELA--ECGALSRPCFENCQEALS-SSKRNDSSVSYPFGTFSPQDKRKD
LLL--PNDGWAESEVPPSP-PPHPGLEWGLEDYGHSSGVDSTVYFPDQHVNFRSVT-PAM
QPESINLKTSKSMDLVPDES--KAQSL---ADRRLDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKSDMPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEEE-ADGLSDKSSHSGHGAL
NCESAPQGNPELDDVENKARKVKKAKEKEKKK-------GKSKLKVKEKKQKEESEDPEK
KMK-RKGFGAMLRFGKKKDDKGGKMEQKSTQ--RPGNLGEEELEKMKGERERIGAKHQEL
REK-QARGLVDYATAAIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPLAYPRDGRPLSPDRDHLEGLYAKVNKPYHPPAPADSGRPMAGNSDRIQKLRKEYYQA
RREGFPFYEDEEGRAWPCDHDLLWVSGKGPDGSTHSLRFEGMERQYASLPRGGSADPVDH
LTAAPRGRYNERELPYYPG--PHPIHVPRGSYPRPPD-LRVADLQYPQYYPRPPA-HQQK
GPFRQDVPPSPPQQQRVPVYQEMGRAGPRGGSPDQHPYRNQDPRQKNPMTAAV

MKVTVCFGRTGIVVPCKEGQLRVRELTQQALQRYLKTREKDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLHKIE--SPGGNPADRQSPDAFETEVTAQLAAFKPV
G--GEIEVTPSALKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDSLQ-SLE
DGEVMNDVQTELLPSPKAKDALS--DVTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPNVLLHVLPPQN
REQYEKSVIGSLNIFGNNDSVL-RTKL-PPPVHGKSGIRTVNLTGTSSPEVDESASLQPS
KS-PRVPRLGRKPSSPSLSPLMGFGSKNNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQDGTFLPRELKGEPG-CYAFSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRDTGMDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPA--ECGVFSKPGFENCQNSVT-TSRRNGSSTLHPSGTYSPQDRRKE
LLL--LNDRWAESEVAPSP-PPHPGLELGLEDYSHSSGADSAVCFTDEHINFRSVT-PAR
QPESISLKASKSMDLVPDES--KVNSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
NCEFAPQGKSELEDLENKTRKVKKTKEKGKKK-------EKGKLKVKEKKQKEENEDPER
KLK-KKGFGAMLRFGKKKDDKDGKAEQKGAL--KHGGLREEELEKMKE-CERVGAKHQEL
REK-QARDLVDYAAGGIGSMHDMDDDE--MDPNY---ARVNHFREPCASASIYSSPSLPR
AGPLSYPRDGRPLSPERDHLEGLYAKVNKSYHPPAPADSGHPTGGSTDRIQMLRKEYYQA
RREGFPLYEDDEGRARPSDYDLHWVSGKSPGGNAHNLSFEGLERQYASLPRGGPVDPVDY
LTAGPRGLYKERELPYYPG--AHPVHPPKGTYPLPPE-LRVTDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRMPAYPEMGRPGPRGGSPDQYPYRAQAPRQKSPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKTE--SPGGNPADRQSPDAFETEVAAQLAAFKPV
G--GEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASLSGQSLKPVVLDSTQ-NVE
NKEAMNGEQAGLLSLHRPKDELS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQN
REQYEKSVIGPLNIFGNNDGAS-RTKA-APPARGKPGLKAVHLTRASSPEGEEPASPQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLESSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEELS--ECGALSRPGFENCQEALS-TSRRNDSSILYPFGTYSPQDKRKD
LLL--PSDGWAENEVPPSP-PPHPALEWGLEDFSHSSGVDSTGYFPDQHVNFRTVT-PVR
QPELINLKASKSMDLVPDEG--KVQSL---ADRRSDSPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAD-ADGLSDKSSRSGHTAL
NCESAPQGNPELDNVENKAKNIKKTKEKEKKK-------GKGKLKVKEKKLKEEHEDAER
KMK-RKGFGAMLRFGKKKDDKVGKAEQKGAQ--KSGHPEEEELERMKEERERIGAKHQEL
REK-QARGLVDYATAVTGPVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPLR
AGPLAYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQA
RREGFLLYEDENTRARPSDHDLRWVSGKGPDGSTHNLRFEGMERQYASLPRGGSADPVDY
LTASPRGRYNDRELPYYPG--PHPVHAPRGSYPRPPD-LRATDLRYPQYYPPPPA-HQHK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKNPMTAAV

MKVTVCFGKTGIVVPCKDGKMSVRELIQQAAQRFIKAKEKEPGYWVKVHHLEYQDGGILD
PDDIVADVVEDKDKIIAVFDEQEASEIKNRNEDSVNVIDRTSPDPLEAELSAQLSAFQPL
K--GEIDVTSSALKIGTPLLVRRSSDPTVGPAVDFHPSSSQSADQNVNDASQGLSRVLPP
D------EQTDQ-NTGLQKPLYKIREITRKVEISGSGGPLGIHVVPFYSSFSGRALGLYI
RGIEESS-RSKREGLFQENECIVKINNVELIDRSFAQAQDIFRQAMKQQNVLVETVLPEK
RELYEKSVISSLFVLDDDIDEVPDIKPPPPPVHVNRSIKMPEQ--VNGIDPTGTKIQQPP
LS-PNLISSESKFSSPSLSPL-GFGNKKNGKKL

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

RIDLTK---GAEGLGFTVVTRDSTVHG
PGPIFVKNILPKGAAVKDGRLLSGDRILEVNGKDIAGKTQEELVAMLRSTKLGESVSLVV

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQDETFLPRELKGETE-NLVFPPDNTAQMTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGISLKGNKSRETGADL
GIFIKSIIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNRDAMETLRRSMSMEGNIRGMIQ
LVILRRLDWQTEERS----ETFQKNTIENLAVSE----------------QNGVQEKLKD
SSR--FNDRNSENYIPPPI-PPHPKEHIIVESPK-----------------LRNVA-ESQ
PNDSLNIKASRSMDI---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

----------------------------------------D

PF12053 // ENSGT00760000119017_2_Domain_0 (42, 147)

PGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPPHKIE--SPDGNPADWQSPDALETEVAAQMASFKPI
S--GEIEVTPSSLKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPRATHPGGQSVRPVVSDSTQ-NLE
DREVMNGVQTELLMSPKIKDALS--DMTRRVDISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVDLVDKTFAQAQDIFRQAMKSPNVLLHVLSPQN
REQYEKSVIGPLNIFGNNDGVS-RTKA-LPPVHGKSGLKTVNLTGINSPEADPSPSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKHAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CYALSLEMSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKARETGMDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPTEETA--ECGAFSKPCFENCQNALA-TSSRNESGILHSFDNYSPQDKQKD
LVL--PHDEWAKCEVPPSP-PPRPSLELGLEDYSYSSGVDSAVYFADQHINFRPMT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGPRPESPNKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDLENKARKVKKTKEKEKKK-------EKGKLKVKEKKQKEENEDPER
KIK-RKGLGAMLRFGKKKDGKRGEAEQKGG-P-KQGNPREEELEKWKGTQERIGAKHQEL
REK-QARGLLDYATGTIGSVHDMDDDE--IDPNY---ARVNHFREPCASANVFRSPSPPQ
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPPAPADSGRPVGGNSDRIQKLRKEYYQA
RREGFLLYEDDEGRPRPTDYDLHWVSGKSPERNAHSLRFEGMERQYASLPRASPADPVDY
LAAAPRGLYSERELPYYPG--AHPVHPPKGGYARPPD-LRVTDLRYPQYYPPPPV-PQHK
GPFRQDVPPSPPRHQRVPAYQEMGRARPQGGSPDRHPYRTQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDILADVVEDKDKLIAVFDEQEPLQKIE--SPSGNPVDRQSPDAFETEVAAQLAAFKPI
S--GEIIVTPSSLKLGTPLLVRRSSDPAPGPHADAQPSAASPSGQSLKPVVPNSTQ-NLE
NREVMNGEQTELLTSHGTKDALS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQN
REQYEKAVIGPLNIFGNSDGAS-RTKV-PPPTRGKPGLKAVTLTGTNSPEADESTSPQQS
KS-PRVPRIGRKASSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVLMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQDGSFLPRELKGEPD-CYTLSLETSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVIIRRLERPLEELT--ECGALSRPCFENCQEALS-PSRRNDSSASYPFGTYSPQDKRKD
LLL--PNDGWAESEVSPSP-PPHPGLEWALEDYSHSSGVDSTVYFPDQHVNFKSVI-PAM
QPESINLKISKSMDLVPDES--KARSL---ADRRLDSPSNDFGPTLGLKKSSSLESLQTA
VAEVRKSDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEVE-ADGLSDKSSHSGHGAL
NCESIPQGNPELDDVENKARKVKKAKEKEKKK-------GKGKLKVKEKKQKEESEDPEK
KMK-RKGFGAMLRFGKKKDDKGGKVEQKGTQ--KPGNLGEEELEKMKEEKERIGSKHQEL
REK-QARGLLDYATGGIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPLAYPRDGRPLSPDRDHLEGLYAKVNKPYHPPALADSGRPVGGNSDRIQKLRKEYYQA
RREGFPLYEDEEGHTRPSDHDLRWVSGKGPDGSTHTLRFEGMERQYASLPRGGSADPVDY
LTAAPRGHYNERELPYYPG--PHPVQPLRGSYSRPPD-LRMADLRYPQYYPRPPA-HQHK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPQGGSPDQHPYRNQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPV
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKPVVPDSTQ-NLE
DREVMNGVQTELLTSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSASVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGIL-KTKV-PPPVHGKSGLKTANLTGTDSPETDASTSLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSRPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKLESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNLELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRYGPALKAELVLIL--------------SLLNKMHAF------PHLQL
HAHSSQLCARSLSA----EV----EEL--FGEAY---RTLS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVYDEQEPHRKSE--GTNGNVTDRSSPDLFEAEVAAQLAAFQPI
G--GEIEVTPSALKLGMPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PALGPPADFHPSASHLSDLSHKHAVAGASQVSFE
DGEMNLTGPTELLSSQRARLPVS--EMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFI
RGIEENS-RSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVILEVLPPYN
REQYEKSAIAPLCFLHNDEEVP-KTKI-PPPVHPKPTLKTINLSGAGSLDAGVLATLQ-A
KS-PNLPRLGRKSSSPSLSPLMGFGNKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSVHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETVCLI

ENSGT00760000119017_2_Linker_1_2 (480, 518)

V
ARQEEAFLPRELKGEPN-CSALSPETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGADL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQ
LVVLRRLEAQTEERL--DQGVYQKSAFDGSHNFAAI--SRRNGAVLQQFVNSGPQERVQD
--LPVSDCGNCENETPPPL-PPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLT-PAK
QSESINLKASKSMDLVADES--KVGSL---AGHRSDASSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVE-EDGFSDKSSHSGQEAQ
NMESVPPGNPEIEDVETKVKKDKKSREKEKKK-------EKGKTKIKEKKRKEENEDPEK
K-K-KKGFGVMLRFGKKKEDKSGKADQKGNP--KHDILKEEDLEKMKDERERIGAKHQEL
RQK-QLRGLLDYSTGPG--GPDIDDDE--VDPNY---ARVNHFREAYPAASIYRPSSPAV
AETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQA
RREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRRGPAEPLEY
LT-GPRVIYKERDLPYYQGGGQPVVHPSKGNYIHAPD-TRVAELRYPQYYPAQSIPNQHK
GPFRQDVPPSPPQPHRAPAYNEIV--RHRGTSPDQYQYRQQDPRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-LPPVHGKSGLKTANLTGAESPETDASTCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDFATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADAVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPAPRGGSPDQYPYRTQDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKIE--SPDGNPVDRQSPDAFETEVAAQLAAFKPV
G--GEIVVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSAASLSGQSLKPVILDSAQ-NVE
NKEVMNGEQTGLLTLHRTNDELS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQN
REQYEKSVIGPLNIFGNNDGAS-RTKA-PPLARGKPGLKAVHPTRANSPEGEEAASPQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRSQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLESSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

ESGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPKRPLEELS--ECGALSRPCFENCQEALS-TSRRNDSSILYPFGTYSPQDKRKD
LLL--PSDGWAENEVPPSP-PPHPALEWGLEDFSHSSGVDSTGYFPDQHVNFRMVT-PVR
QPELINLKASKSMDLVPDEG--KIQSL---ADCRSDSPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAD-TDGLSDKSSRSGHAAL
NCESVPQGNPELDNVENKAKNIKKTKEKEKKK-------GKGKLKVKEKKLKEEHEDAER
KMK-RKGFGAMLRFGKKKDDKIGKSEQKGTQ--KSGHPEEEELERMKEERERIGAKHQEL
REK-QTRDLVDYAVAVTGPVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPPR
AGPLAYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQA
RREGFLLYEDENARARPSDHDLRWVSGKGPDGSAHNLRFEGMERQYASLPRGGSADPVDY
LTASPRGRYNDRELPYYPG--PHPVHTPRGSYARPPD-LRATDLRYPQYYPPPPA-HQPK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKNPMTAAV

MKVTVCFGRTGIVVPCKEGQLRVRELTQQALQRYLKAREKXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLIAVFEEQEPLHKIE--SPSGNPAGRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQDVFRQAMRSPSMLLHVLPPHH
REQYEKSVIGTLSFVGNNDGAL-KTKLPPAAAPGKP----GIMPGTSSPEEDISTSLQQS
KS-PRLPRVPRKLASPSLSPLMGFGSKKNTKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGQTQEELVAMLRSTKQGEIASLVI
ARQEGTFLPRELKGEPA-CYALSLDTIEQLTFEIPLNDSGSAGLGVSLKGNKSRETGTDF
GIFIKSIIHGGAAYKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXEPA--ECGTYSKQCFGNCQSSLA-TSRRNGNSPPHRFGPYSPQDKK-E
PLF--STDGWSESEVPPSP-PPHPILELGLEDYNHSPGMESTVYFPDQHINLRYVA-PAR
QPESMNLKASKSMDLVPDES--KVHSM---AGHKLASPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADSLSDKSSQSGQGAL
NYESVPQGTSELEDMDSKAQKAKKMKEKEKK-------KEKSKLKAKQKKQKEENEDPER
KTK-LKGFSAMLRFGKKKDDKGGKADQKGTL--KHGGLREEELEKMREEREXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXX--XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGRVTGGSADRIQKLRKEYYQA
RREGFTLYEDDEGRAKPSDYDLHWXXXXXXXXXXXXXXXXXXXXXXXXXXXGGPANPMDY
RMAAPRGLFKEREIPYYPG--AHPGQPPKGGYPRPPD-LRVTDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRVPAYPEMGRSGPHGGSLDQYPYRTQDPRQKNPMTAAV

------------------------------------------------------------
-------------M

PF12053 // ENSGT00760000119017_2_Domain_0 (75, 147)

LIAVFDEQEPLHKIE--SPSGNPAGRQSPDAFETEVAAQLAAFKPI
G--REIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPRASHPSGQSLKPVILDSTQ-NLE
DEEVMNGVQTEPLTSLKTKAALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGVL-RTKPQPPVH-GIAGIKTVTLTGTGGPEEDALTSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 519)

I
ARQEGTFLPRELKGEPD-CYALSLETTEQLTFEIPLND

PF00595 // ENSGT00760000119017_2_Domain_2 (519, 590)

SGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEEPA--ECGAFSKPCFENCQNTIT-TSRRNDNSSLHPFGTYSSQDKQKV
LLL--PSDGWADPEVPPSP-PPHPVLELGLEDYSHSSGVDSVAYFPDQHIHFRSVT-PAR
QPESMNLKASKSMDLVSDES--KVHSL---AAHKSDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
SCESVPQGSPELEDGEQKARKIKKPKEKEKK-------KEKGKLKAKEKKLKEENEDPER
KIK-KKGFGAMLRFGKKKDDRGGKTEQKGSL--KHGALTGEEREKMK-ERERIVAKHQEL
REK-QARGLLDSAAGATGSLHDMDDDE--MDPNY---ARVNHFREPCAS-SVYRSPSPPR
AGPLGYHRESRPLSPERDHLEGLYAKVNKPYHPLVPAESGRPASGSTDRIQKLRKEYYQA
RREGFTLYEDDEGRARL-DYDLHWVSGKGPDGNAHNVRFEGMERQYASLPRGGPADPVDY
LTATPRALYQERELPYYPG--VHPVRPPKGSYPRPPD-LRVADLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQQHRVPANPEMGRPGPRGGSPDQYPYRAQDPRQKSPMTAAV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MNGVQTELLTSLKTMDALS--VMTKTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLTDKTFAQAQDVFRQAMKSPSVLLRVLPPQN
REQYEKSVIGPLHIFGNNDGAS-RTKV-PPSIHGKSGVKMVNPTGSNGPKDDASTSLQQS
RS-PRVPRVGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGTFLPRELKGEPD-CYALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPVEEAA--ECGAFSKPGFESCQNALT-TSRRNDNSPSHPFGTCSPQDKQKE
STL--PNDRWAESEVPPSP-TPHPVLELGLEDCSHSSGVDSAVYFPDQHFNFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVRSL---AEHKPESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRTHMVRGRGCNESFRAAIDKSYDGPEEFE-ADGLSDKSSHSGQGAL
NCELAPQGSSELENVENKARKIKKTKEKEKKK-------EKGKLKVKEKKQKEGNEDPER
KIK-RKGFGAMLRFGKKKDDKGGKAEQKGPL--KRGGLREEELEKMKEERERIGAKHQEI
REK-QARGLIDYATGAVGSLHDMDDDE--MDPNY---ARVNHFREPCTSANVYRSPSPPR
AGPLGYPRDGRPLSPERDHLEGLYAKVNKPYHPPVPIDSGRPMSGSADRIQKLRKEYYQA
RREGFALYEDDEGRARP-DYDLHWVSGKGPDGNLHNLHFEGMERQYASLPRGGPADPVDY
LTAAPRGLYKERELPFYPG--AHPVHPPKGSYPRPPD-LRLTDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRVPAYQEIGRPGPRGGSPDQYPYRTQDPRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
----------------------------MGPPADFYPGAAHPTDNGLIPVVTGATLLSFE
DGEMDLTGHTEQLTSQKAKFTFS--CMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSRRDDLFHENECIVKINNVDLTDKTFAQAQDIFRQAMKSPSVFLEVVPPYN
RELYEKSVIAPLCLLDN-DGVP-KTKV-PPPVITKPTVKR-DLSGMNGLETDLHSTLQHT
KS-PNLPRLGKKPSSPSLSPLMGFGNKKNAKRIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSVHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGKDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 519)

V
ARQEEAFLPRELKGEPN-CSLLSLETTEQLTFEIPLND

PF00595 // ENSGT00760000119017_2_Domain_2 (519, 589)

SGSAGLGVSLKGNKSRETGADL
GIFIKSIIHGGAAFKDGRLRINDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVVLRRLDRQMQERS--DHGLFQKPALEGSQAFTAV--SRCNDSVLQQFITYSPQERLKV
SELTVSDYGSGENEVPPPI-PPHPSEEQLSEDYNHSSVVDSAAYLTDQNFSFRSLT-PAK
QPESINLKASKSMDLVADES--QVSSL---AGHKQESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEDAE-EDGLSDKSSLSAQETQ
NFEATPQGNPELEDVETKIKKDKKYKEKEKKK-------GKIKGKVKEKKRKEENEDPEK
KTK-KKGFGAMLRFGKKKEEKGGKDDQKGNP--KHGTLREEELEKMKDERERIGAKHQEL
RQK-QARGLADYSTSPISPPPDIDDDE--MDPNY---ARVNHFREAYPAANVYRPSSPPA
AETFGYPHDIPTKPGEREHLEGLYAKISKQHHPQNPADSGCPAVGNADRIQKLRKEYHQA
RRDGLPFYEDDEMRTRPSDYDQYWVSGKGPDGSSHNLHFEGMERQYASLPRCGPAEPMEY
LT-GPRVMYKERDLPYYQG-GQPAVHPSKGNYSRAQD-LRAAELRYPPYYPAQHLTTQHK
GPLRQDVPPSPPQMHRVPAYNETSRTRQRGSSPDQYQYRQPDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRGQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEGEPIRKTE--SPGGNPAEPQSPDACETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSE

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPSAAHPGSQSLKPVVPESTQ-SLE
DREVMNGEQTELLTSPKIKDALS--DMTRTVAISGEGGPLGIHVVPFFSSLSGRVLGLYI
RGIEENS-RCKREGLFQENECIVKINDVELVDRTFAQAQDIFRQAMKTSSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-RTKM-PPPAHGKPGLKAVNLTRANSPEVDESSSLQQS
KS-PRVPRLGK-SSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGKDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CYALSPETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGEALLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRKHERPVEELA--ECGVLSKQCFENCQNALT-TSRRNDTNILYPFGTYSPHDTKKD
LFF--PNDGWTEREGPPSP-PPQPGLELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAM
QPESINLKASKSMDLVPDES--KVQSL---AGRRSESPNKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNQSFRAAIDKSYDGPEEAE-ADGLSDKSSHSGQTPL
NWESAPQGSSELEDMENKTRKVKKQKEKEKKK-------EKGKLKVKEKKRKEENEDPEK
KMK-RKGFGAMLRFGKKKDDKGGKADQKGAL--KTENLGEEELEKMKEERERIVAKHQEL
REK-QARGLVDYATGAIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSASPPR
AGPLSCPRDGRPLSPERDHLEGLYAKVNKPYHPPAPADSGRPMGGSTDRIQKLRKEYYQA
RREGFPVYEDEEGRARPSDYDLHWVSGKGPDGNAYNLRFEGMERQYASLP----------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADAQPSTSPPGVQGLKLVIPDSTQ-NLE
DREVMNGEQTELVTLPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREELFHENECIVKINNVDLVDKTFAQAQDVFRQAMRSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNSDGIL-KTKV-PPPVHGKSGIKTANLTRTDSPETDASASLQQS
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNNEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSRPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-APHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
EPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDVENKARKVKKAKEKEKKK-------EKGKLKAKEKKRKEENEDPDR
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPQ
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLGPVDSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSDYDLLWVSGKGPDGNAHSLRFEGMERQYASLPRGGPTDPVDY
LPAAPRGIYKERELPYYPG--SHPMHPPKGSYPRPAE-LRVADLQYLQHYPPPTA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDRYPYRTQDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAEQQSPDAFETEVASQLAAFKPV
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPVASHPGGQSLKSVVPDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-PPPVHGKSGLKTANLTGAESPETDASTSLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVVLRRPERPMEDPA--ECRAFSKPCFESCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDRWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKMKEKEKKK-------EKGKLKVKEKKRKEENKDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDNEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
----------------TPLLVRRSSDPAPGPPAGAQPGVSHPGGQSLKPVVPDSTQ-NLE
NGEGMNGRQTELPTSPKTKDVLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKQEGLFQENECIVKINNVDLVDKTFAQAQDVFRQAMRSPAVLLHVLPPQN
REQYEKSVIGPLSIFGNSDGGL-KTKA-PPPILGKSGLKTANFTGANSPEADALTFLQHS
KS-PRALRLERKPPSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTRQGETASLLI
ARQEAHFLPREL------------------------------------------------
---------------DGRLRTNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPAEETA--ECGAFSKPGFENCQNAEP-ASRRHDNGTLHRLGTH-AQDKQKD
LLP--PGDGWARSEVSPSP-PLH----PALEDHGHSSGVDSAVYFPNSHISFRSVT-PAR
QPELINLKASKSMDLVPDES--KVHAL---AEHKAESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGHGAL
NGESAPQGTPELEDIENKARKVKKMKEKEKKK-------EKGKLKVKEKKRKEENEDPDR
KMK-RKGFGAMLRFGKKKDDKGGKAEQKGAM--QHDGPREEALERMREERGRIGAKHQEL
REK-QARGLVEYATEAAGSMHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPREGRPLSPERDHLEGLYAKVNKPYHPPTAVDSVRPVGGSSDRIQKLRKEYHQA
RREGFPSYEDDEGRARPSDYDLLWXXXXXXXXXXXXXXXXXXXXXXXXX-----------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------S--EMTKTVEISGEGGPLGIHVVPFFSSLSGRLLSLFT
VGIKFTSRRSRRNGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVILEVLPPYN
REQYEKSAIAPLCFLHNDEEVP-KTKI-PPPVHPKPTLKTINLSGAGSLDAGVQATLQ-A
KS-PNLPRLGRKPSSPSLSPLMGFGNKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSVHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETVCLIV

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEEAFLPRELKGEPN-CSILSPETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGADL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQ
LVILRRLEAQTEDRL--DQGVYQKSACDGCHNFAAI--SRRNGAVLQQFVNCGPQERIQE
--LPVSDCGNCENETPPPL-PPHPSEDLLNEDHNHSSLWHLSFIFPFQSIKFRNHLGVFR
QKQHPNIFRTELTPTVADES--KVGSL---AGHRSDASGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVE-EDGFSDKSSHSGQEAQ
NMESVPPGNPEIEDVETKVKKDKKNREKEKKK-------EKGKTKIKEKKRKEENEDPEK
K-K-KKGFGVMLRFGKKKEDKSGKADQKGNP--KHDILKEEDLEKMKDERERIGAKHQEL
RQK-QLRGLLDYSTGPG--GPDIDDDE--VDPNY---ARVNHFREAYPAASIYRPSSPAV
AETFVYPRDSSSTPMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQA
RREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHFEGMERQYASLPRRGPAEPLEY
LT-GPRVIYKERDLPYYQGGGQPVVHPSKGNYIHAPD-ARVAELRYPQYYPAQSVPNQHK
GPFRQDVPPSPPQPHRAPAYNEII--RHRGTSPDQYQYRQQDPRQKNPMTAAV

----------------------------------------DPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLHKIE--SPTGSQADPQSPDAFETEVAAQLAAFRAI
G--GEIEVTPSALRLGTPLLVRRSSDPALGPPADTQPRASHPGGQSLKPVVVDSMQ-SLE
DGETMNGMQTERPISPKTKDTSS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEDNS-RSKREELFHENECIVKINNVDLVDKTFSQAQDVFRKAMRAPSVLLHVLPPQN
REQYEKSVIRTLNIFGSNDGIL-RTKV-P-PVHNKSGVNTTNPTGTSSTEADTTTSPQQS
KS-PQMPRLGRKPSSPSLIPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTERTQEELVAMLRSTKQGETASLVI
ARQEGNFLPREL------------------------------------------------
---------------DGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPPEEPA--ECGAFSKPGLENCQNAVMTTLRRNDSSPLQPFSTYSPRDRQRD
LLL--PRDGWAGSEGPPSP-APHPGLELGLEDYSHSGGVYSSIYVPDQNINFRSVT-PAQ
QAESINLKVSKSMDLVPDES--KVHSL---AGHKSESPCNDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELEAXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX-------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXMLRFGKKKDDKGEKAVQKGTL--KLGGLKEEELEKMKEEQDRIGAKHQEL
REK-QTRGLIDYATTAMGSVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPPR
AAPLGYPRDGRPLSPERDHLEGLYAKVNKPYHPPAPVDSGRPVTGNTDRIQKLRKEYYQA
RREGFPLYEDGDGRARPSDYDLHWVSGKSPEGNTHSLRFEGIERQYASLPRGGPADSVDY
LTAAPRGLYKERELPYYPG--AHPMHPPKGSYPCVPD-LRVADLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHQRVPGYPEMGRPVPRG-SPDHYPYRTQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPV
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPVASHPGGQSLKPVVPDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNSDGIL-KTKA-PPPVHGKSGLKTANLTGAESPETDASTSLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQDGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGAYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KMK-KKGFSAMLRFGKKKENKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYGTGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDNEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MNSTE-ELE
DGEVMNGMQTELLTSPKTMDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDLFRQAMKSPSVLLRVLPPQN
REQYEKAVIGPLNIFGNNDRML-RTKE-PPPVQGKSGIKTINLTGTSSPEEDASTSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGTFLPRELKGEPD-CCAFSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPA--ECGAFSKPCFENCQNAVS-TTRRNDSSTLHPFGTYSPQDKQKD
LAL--PSDGWAESEVPPSP-QPHPALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVHSL---AGHKSDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDRSSHSGQGAL
NCESAPQGNSELENAENKARKVKKTKEKEKKK-------EKGKLKVKEKKQKEGNEDPEK
KIK-KKGFGAMLRFGKKKDDKGGKAEQKGPL--KQGGLREEELEKMKEERERIGAKHQEL
REK-QARSLIDYATGAIGSLHDMDDDE--VDPNY---ARVNHFREPCTSANVYRSPSPPR
AGPLGYPRDGRPLSPERDHLESLYAKVNKPYHPPVPADSSRSMSGSADRIQKLRKEYYQA
RREGFALYEDDEGRARP-DYDLHWVSGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LTAASRGLYKERELPYYPG--AHPVHPPKGSYPRPPD-LRVTDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRVPAYPEMGRPGPRGSSPDQYPYRTQDPRQKNPMTAAV

------------------------------------------------------------
--------------IWMFILKTQPLHKIE--SPSGNLAGQQTPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPAPGPPADAQPSASQSSGQSLKPVTLDSTQ-NLE
DGEVMNGVQTELLASLKTKDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINHVDLVDKTFAQAQDVFRQAMKSPSVLLNVLPPQN
RDQYEKSVIGPLNIFGDNDGVL-RTKLPPPVH-GISGIKTG--TGTGRPEEDASTSLQQN
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGAFLPRELKGEPD-CYPLSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPT--ECGAFSKPCFENCPNAIN-ASRRNDNSSLHPFGTYSSQDKQKE
LLL--PSDGWAEAEVPPSP-PPHPVLELGTEDYSHSSGVDSAVYFPDQHTHFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVHSL---ADHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSRSGQGAL
NCEAAPQGSSELEDVENKARKIKKPKEKEKK-------KEKGKMKVKEKKLKEENGDPER
KIK-KKGFGAMLRYGPADSFAFWLSLLFSQM--GK-NLNCECACSFS-------------
--A-EAEGAF---LGGSGSSW---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKLVVPDSTQ-NLE
DREVLNGVQTELLTSPRTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEDNS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGVL-KTKV-PPPVHGKSGLKTANLTGTDSPETDASASLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSNKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSILHPLGTCSPQDKQKG
LLL--PNDGWAESEVPPSP-TPHSALGLGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGQKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSEYDLLWVPGRGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

----------------------------------------G

PF12053 // ENSGT00760000119017_2_Domain_0 (42, 83)

PGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKPVVPDSTQ-NLE
DREVLNGVQTELLTSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGVL-KTKV-LPPVHGKSGLKTANLTGTDSPETDASASLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIR

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPVEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSILHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGQKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------DSTQ-NLE
DGEVMNGVQTELLTSPKIKDALSPSDLTRTVEISAEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFQENECIVKINHVDLADKTFVQAQDVFRQAMKAPCVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVS-RTKP-PPPVHPRSGIKTVSLTGTSSPEEDGSPSLQQS
KS-PRVPRIGRKPSSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGAFLPRELKGEPD-CRALSPETTDQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDM
GIFIKSVIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPG--ECGTFSKPCSENCHSAVA-TCRRSEDGTWHPLSTYCPHHKQRE
PLL--PSDGWAESEVPPSP-SPLPVLELGLEDYSHSSGMDPAVYFPDQHSNFRSVT-PAR
QPESMSLKASKSMDLVPDES--KVHSL---AGHKLESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEDLDGTDGLSDRSSHSGHGAL
NCDSAPPGNSEPEDLENKARKAKKTKEKEKKK-------EKGKAKGKEKKQKEESEDPER
KIK-RKGLGAMLR-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFI
RGIEENS-RSRRDGLFHENECIVKINHVDLTDKTFAQAQDIFRQAMKFQSVILEVLPPYN
REQYEKSAIAPLCMLNNEEGVT-KTKI-PPPLHPKPAVKTINISGA-SLESGVQGTLQQA
KS-PNLPRLGRKPSSPSLSPLMGFGSKRNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSVHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETVCLI

ENSGT00760000119017_2_Linker_1_2 (480, 518)

V
ARQEEAFLPRELKGEPN-CSFFSPETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGADL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQ
LVVLRRLELHAEERS--DQGVFQKSALDRSHNFAAA--SRRSDTILQQFITCSPQEGIKE
-F-QVSDHGSGENETPPPL-PPHPSEDLLNEDYNHSPIINSAVHLTDQHINFRSLT-PAK
PSESINLKASKSMDLVADESK--VGLL---AGHKSDSSGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDEE-DGG-SDKSSHCGQEAQ
NVESAPPGSPEIEDAEIKQKKDKKSREKEK---------KKGKSKIKEKKKKEENEDPEK
R-K-KKGFGVMLRFGKKKEDKSGKADQKETP--KQGMLKEEELEKMKDERERISAKHQEL
RQK-QLRGLSDYSTGPG--GPDIDDDE--VDPNY---ARVNHFREAYPPAGIYRPSSPAV
GETFVYLRDSSSAPMEREHLEGLYAKINKQHYPQTSGDSGCAGGGNADRIQRLRKEYHQA
RREGLPFYEDDEGRTQLSDYNQCWVPGKGPDGSSYSLHFEGVERQYASLPRRGPAEPLEY
LT-GPRVTYKERDLPYYHG-GQPVVHPSKGNYIRAPD-TRVAELRYPPYYPAQPIPNQHK
GPLRQDVPPSPPQPHRAPAYSEIV--RHRGTSPDQYQYRQQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKIE--SPSGNPVDRQSPDAFDTEVAAQLAAFKPI
G--GEIVVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSTASPSGQSLKPVVLDSAQ-NLE
NRDVMNGEQTGLLMLHKTKNELS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQN
REQYEKSVIGQLNIFGNNDSAS-RTKA-PPPTRGKAGLKAVNPTRANSPEGEESPSPQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLESSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRLERPLEEIS--ECGALSRPCFENCQEALS-ASRRNDSSLLYPCGTYSPQDKRKD
LLL--PSDGWAENEVPPSP-PPHPSLEWGLEDFSHSSRVDSTGYFPDQHVNFRIVT-PVG
QPESINLKASKSMDLVPDES--KVQSL---ADRRSDSPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAE-ADGLSDKSSHSGHTAL
NCESAPQGNPELDDVENKAKNVKKTKEKEKKK-------GKGKMKVKEKKQKEEHEDTER
KMK-RKGFGAMLRFGKKKDDKVGKTEQKGTQ--KSGHPGEEELERMKEERERIGAKHQEL
REK-QARGLVDYATVATGPVHDIDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGTLGYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQA
RREGFLLYEDEEGVTRPSDYDLHWVSGKGPDGSAHNLRFEGMERQYASLPRGGSADPVDY
LTASPRGRYNERELPYYPG--PHPVHSPRGSYPRPPD-LRVTDLRYPQYYPPPPA-HQHK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPRGGSPDQYPYRNQDPRQKNPMTAAV

-----------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (42, 147)

PGDWVKIHHLEYMDGGILD
PDDILADVVEDKDSLIAVFDEQESIHKVE--SPSGNLTESHSPDSFDAEVATQLAAFKPI
G--GEIEVTTSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PALSPPADSHPGASHPSDQNLKPVVPVSME-ILR
MRDQVVTVHTQLLTSKNLKLFLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKRDGLFHENECIIKINNVDLIDKTFAQAQDVFRQAMKSQNVLLQVLPPNN
REQYEKSVIAPLGIFGNSDAAS-RTKA-SPPIQGKPALKTISPTGASSPETNTQISLQQK
RS-PRIPRVGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 519)

I
ARQEENFLPRELKGEPDHCYVLSLETPEQLTFEIPLND

PF00595 // ENSGT00760000119017_2_Domain_2 (519, 590)

SGSAGLGVSLKGNKSRETGADL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRLDRQTEDRS--DYGLFPKPSLESCQHFVTT--SRHHEPNPHPFLTYGPHSLFIE
LLL--PDTDWAENDIPPPL-PPHPSLELDLEDYNHSSVVDSAVYCTDQQINFRSLT-PAK
QPESINLKASKSMDLVPDES--KVHSL---AGHRLEPTAKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPENLE-EDGLSDKSSRSGQGAL
NCESNPQGNAVLEDIENKAKKDKKNKDKEKKK-------EKGKLKVKEKKRKEDSEDSEK
KVK-KKGFGAMLRFGKKKEDKGGKNEQKGNL---KQGILQEELEKMKEESERIGAKHQEL
REK-QARGLIDYSAGLLGTLHDMDDDE--MDPNY---ARVNHFRDTYVPAGVYRSSSPPR
IGTLGYLRDGPPLSLEKDPLEGLYAKINKPYHPQTLADSGRPTSGSTDRIQKLRKEYHQA
RREGFSLYEDEELRARPSDYEQHWVSGKSPDGSSHNLRIEGMERQCASLPRRGPTDPTDY
LTGPPRLIYKERELPYYPG--VQPLHPPKGSYPPTQ------ELRYPQYYPAPPA-SHHK
GPYRHDVPPSPPQHPRVPAYHELGTTGQRAASHEQYPYR--DPRQKNPMTAAV

-------------------------------------------------MPCLCDVPVL-
---ESDECYWPCL

PF12053 // ENSGT00760000119017_2_Domain_0 (74, 147)

QLIAVFEEQEPPCTTE--SPGGNPAGRQSPDALDTEVAAQLAAFKPV
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPRAAHPGGQSVRPVVSDSTQ-ELG
GREVMNGVQTELFTAPRTKDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKREGLFQENECIVKINSVELVDKTFAQAQDVFRQAMKSPHVLLQVLSPQN
REHYEKSVIGPLHIFGNSDGVL-RTKV-SPPVHGKSGLKTANLTGANGPEADPATSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI
ARQEGSFLPREL------------------------------------------------
---------------DGRLRVNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPTEETA--EWGAFSKPCFENCQNVLP-ASSRNESGILHSFDNYGPQDKQKE
LVL--PHDEWASGEAPPSL-PPHPG-----------SGVDSAVYFPDQHINFRSMT-LAR
QPESINLKASKSMDLGKLDRG-DIQSI---YG-QKSSFAFYFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSHSGQGAL
NCESAAQGNSELQDLENKARKVKKTKEKEKKK-------EKGKLKVKEKKVEENRNK-ER
KVKFKVTVFVGLKFGKKKDGKRGEAEQKGG-P-KPGSPRPEEPEPREAERARIGAKHQEL
REK-QARGLLDYATGTIGSVHDMDDDE--IDPNY---ARVNHFREPCASANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYQPPVPVDSGHPAGGSSDRIQKLRKEYYQA
RREGFLLYEDDEGRPRPSEYELHWVSGKSPDGNAHNLRFEGMERQYASLPRAGPADPVDY
LTAAPRGLYQERELPYYPG--AHPVHPPKGGYARPPE-LRMTDPRYPQYYPPPPV-PQHK
GPFRQDVPPSPPRHQRMPAYQEMGRAGPRGVSPDRHPYRTQDPRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MNGVQTELLTSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSASVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGVL-KTKV-PPPVHGKSGLKTANLTGTDNPETDASTSLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPVEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDRWAESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

MKVTVCFGRTGIVVPCKEGQLCVRELTQQALQRYLKTREKXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLIAVFDEQESLHKIE--SPSGNLADRQSPQALEREVAAQLASFNPT
G--GEIEVTPSALSSGTPLLVRRSSDPAPGPPADVQPSASHSSGQSLKLVVP---Q-DIK
DGEVMNGEQTEFVTSPKIKDALR--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFTQAQDVFRQAMKSPSVLLHVLSPPD
REDYEKSVIGALNIFGNSDGIL-RTKP--SVP-GKSEMKAVSLIGTNSPEVEASTFLQQA
RS-PRIPRQGRHPSSPSLSPLMGFGSKKNAKSI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETAALVI

ENSGT00760000119017_2_Linker_1_2 (481, 510)

ARHEGHHLPRELKGEPD-CCVLSLETTEP

PF00595 // ENSGT00760000119017_2_Domain_2 (510, 590)

LTF-IPLNDSGSAGLGVSLKGNKSRESGTDL
GIFIKSVIHGGAAFKDGRLRVNDQLIAVNGESLLGKSNHEAMETLXXXXXXXXXXXXXXX
XXXXXXXXXXXXEVA--ECGAFSKPCLENCQNPVA-TSRRNENSSLRPFGTSSPQDKWQE
RLL--HGERWTESEVPPSP-PPHPSLELGLEDYSHSSGVDLAVCFPDQHINCRSAT-PAR
QPESINLKASKSMDLVPDES--NVYSL---AAQKSEAPGKDFGPTLGLKKSSSLESLQTA
VAEVTKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEFG-NDGLSDKSSYSGQGTL
HCESAPPGNSELEDTENKARKIKKTKEKEKK-------KEKGKLKVKEKKQKEETEEAER
KVK-RKGFGAMLRFRKKREDKDGKAEQKGAL--KQEELQKTQDER-----EXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XXXXXXXXXXXXXXXX-XXX--X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGRPPGGSSDRIQKLRKEYYQA
RREGFSLYEDDEGRPRPSDYDLHWVPGKGPDGNAHHLRFEGMERQYASLPRGGP---VDY
LTAGPRGLYKERELPYYSG--AHPAHPPKGGYPRSPD-LRVADLRYPQYY-------QHK
GPFGQDVPPSPPQHHRAPAYQEVGRAGPRRGSPDQYPYQTQDPRQKNPVTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPGASHPGGQSLKPVVSDFMQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-PPPVHGKSGLKTANLTGAESPETDASTCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSEYDLLWVPGKGPDGNAHNLRFDGLERQYASLPRGGPTDAVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

MKVTVCFGRTSIVVPCKEGQLHVRELTRQALQRYLRTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPTGNPADRQSPDAFETEVAAQLAAFKPI
G--REIEVTPSALKLGTPLLVRRSSDPVSSPPTDAQPSPSHPSGQSLKPVIPDSTP-KLE
DREVLNGAHSEHLTLLKTKDVLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFQENECIVKINHVDLVDKTFAQAQDVFRQAMKTPSVLLHVLPPQN
REQYEKSVIGPLGIFGNNDGVL-KTKSSPAVH-GKSGVKTINLPGTNSPEEEAPDSLQQS
KS-PRVPRVPRKPPSPSPSPLMGFGNKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSMHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGQTQEELVAILRSTKQGETASLLI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGSFLPRELKGEPD-CYAFVPENIEQLTL

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDF
GIFIKSIIHGGAAFKDGRLRVNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRLERPVEESA--ECGAFSKPCFENCQNSVV-TTKRNDNSAVHTFGTCNPQDKQKE
PLL--PHDGWAESEIPPSP-PPHPILELGLEDYSHSTEMDSAVCFPDQHINFRCMT-PAR
QPESMNLKASKSMDLXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXSLSDKSSHSGQGAL
NCEPATQGNTELEDTENKTRKVKKLKEKEKK-------KEKSKLKIKEKKQKEENEDSEK
KTK-KKGFGAMLRFGKKKEDKNGKTEQKGTL--KHGGLKEEELEKMKEEREXXXXXXXXX
XXX-XXXXLVDYATGAMGTLHDMNDDE--MDTNY---ARETHFRDPCASATVYRSPYPPQ
TGPLGYSRDGHPLS-ERDYLEGLYAKVNKPYHPPVQVDSGRPLSGSTDRIQKLRKEYYQA
RREGFTLYEEDEGRTRPSEYELHWVPGKGPDGNAHNLRFEGMERQYASLPRGGRADHVDY
LAAAPRGLYKERELPYYPG--PHPVHPPKGGYPRPPD-LRVADLRYPQYYPPPPA-PQYK
GPFRQDVPPSPPQHHRVPAYQEMGRPPPRGSSPDQYPYRAQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKIE--CPSGNPVDRQSPDAFETEVAAQLAAFKPI
G--GEIVVTPSALKLGTPLLVRRSSE

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSAASQNGQSLKPVVPDSTQ-NLE
NKEAMNGEQTELLTSHRTTDTLS--EMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEEHS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQN
REQYEKSVIGPLNIFGNKDGTS-RAKV-PPPARGKAALQAANLAGTHSPEADETISLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRVLEVNGRDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYMLSLEASEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETRTDL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPQEEPT--DCGVLSRPSFENCQEALS-TSRRNDGSPLYPFGTYSPQNRRKD
LLL--PNDGWAENEVPRTP-SPHPALEWGLEDYSHSSGVDSTVYFPDQHVNFRSVT-PVM
QSESVNLKASKSMDLVPDES--EVQSL---ADRRPDPPSKDFGPTLGLKKSSSLESLQTA
VAEVRKSDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAE-ADGLSDKSSHSGHGAL
NCESAPQGNPELDNMENKGRKVKKPKEKEKKK-------GKGKLKIKEKKQKDESEDPER
KMK-RKGLGAMLRFGKKKDDKGGKVEQKGTQ--KPGNLGEEELEKMKEEMGRIGGKHQEL
REK-QAGGLVDYAAGATGPVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPLAYPRDGRPLSPDRDHLEGLYAKVNKPYHPPALADSGRPMTGNSDRIQKLRKEYYQA
RREGFPLYEDEEGRAGPCDHDLRWVPGKGPDGSTHNLRFEGMERQYASLPRGGSADPVDY
LMAAPRVRYNERELPYYPG--SHPVHPPRGGYPRPSD-LRAADLQRPQYYPRPPA-HQHR
GPFRQDVPPSPPQHHRVPVYQEMGRAGPRGGSPDRHRYGNQDPRQKNPMTAAV

------------------------------------------------------------
--------------LIAVFDEQEPLHKIE--SPSGNPAGRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPAPGPPADAQPSASHPSGQSLKPVILDSTQ-NLE
DGEVMNGVQTEPLTSPKTKDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-RTKLPPPVH-GISGIKTINLTGTGSPEEDALTSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAVLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGTFLPRELKGEPD-CYALSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEEPA--ECGAFSKPCYENCQNTIT-TSRRNDNSSLHPFGTYSSQDKQKE
LLL--PRDGWAEAEVPPSP-PPHPILELGTEDYSHSSGVDSAVYFPDQNIRFRSVT-PGR
PPESMNLKASKSMDL---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPGASHPGGQSLKPVVSDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGVEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-PPPVHGKSGLKAANLTGAESPETDASSCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSDYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADAVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-SQHK
GPFRQDVPPSPPQHQRMPAYQETGRPAPRGGSPDQYPYRTQDSRQKNPMTAAV

------------------------------------------------------------
---------------------------ME-

PF12053 // ENSGT00760000119017_2_Domain_0 (91, 147)

-SPSGNSAGRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPSASHPSGQSLKPVILDSTQ-NLE
DGEVMNGVQPEPPTSPKTKDALS--DMTKTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPNVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-RTKLPPPVH-GISATKTVNLTGTGSPEEDALTSLQQS
KS-PRVPRQGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 519)

I
ARQEGTFLPRELKGEPD-CYALSLETTEQLTFEIPLND

PF00595 // ENSGT00760000119017_2_Domain_2 (519, 590)

SGSAGLGVSLKGNKSRESGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEEPT--ECGTFSKPCFENCQTTIA-TSRRNDHSSLHPFGAYSSQDKQKE
LLL--PSDGWAESEVPPSP-PPHPILELGTEDYSHSSGVDSAVYFPDQHIHFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSVSGQGAR
HCESAPPGSCEQEDVASKASKIKKPKEKEKKK------KEKSKLKAKEKKLKEDNEDPER
KIK-KKGFGAMLRFGKKKDDRGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLIDYATGAIGSLHDMDDDE--MDPNY---ARVNHFREPCASPSVYRSPSPPR
AGPLAYHRDGRPLSPERDHLEGLYAKVNKPYHPPVPVDSGRPTNGSTDRIQKLRKEYYQA
RREGFTLYEDDEGRARL-DYDLHWVSGKGPDGTAHNVRFEGMERQYASLPRGGPADPIDY
LTAAPRGLYKERELPYYPG--AHPVHPPKGSYLRPPD-LRVADLRYPQYYPPPPA-PQPK
GPFRQDVPPSPPQHHRVA-YQEMGRPGPRGGSPDQYPYRAQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKIE--SPSGNSMDRQSPDAFETEVAAQLAAFKPL
G--GGIVVTPSALKLGTPLLVRRSSE

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQTSAASPSGQSLKPVVPNSTQ-NWE
NREVMNGEHTELLSPHRTKDTLS--DMTRTVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLVPQN
RERYEKSVIRPLNIFGNNDGTL-RAKA-VPPARGKPGLKAANLPRPNSPEADESNSPQQS
KS-PQVPRQERKPASPSLSPFMGFGSRKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGKTQEELVAILRSTKQGETVLLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEESFLPRELKGEPD-CYALSLETSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLVAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEGLA--ECGAFSRPCFENCQEAPS-TSRRNDSSILYPFGTYSPQDKRKD
LQP--PSDGWAESEVPPSS-PLHPGLEWGLEDYNHSSGVDSTVYFPDQPVNFRSVI-PAM
QHESINLKTSKSMDLVPDES--KAQSL---ADRRSDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEGE-ADGLSDKSSHSGHGAL
NCESAPQGNPELDDVETKARKVKKPKEKEKKK-------GK--QKVKEKKQKEESEDPER
KMK-RKGFGAMLRFGKKKDDKVGKVEQKGTQ--KPGHQGEEELEKMKEERERIGAKHQEL
RER-QARGLVDYAPGAIGSAHDMDDDE--MDPNY---ARVNHFREQGTSANVFRSPSPPR
AGSLAYPRDGRPLSPDRDHLEGLYAKVNKPYHPPALADSGRPMAGNNDRIQKLRKEYYQA
RREGFSLYEEEEGRTRPSDHDLRWVSGKGPDGSAHSLRFEGMERQYASLPRGGSADPVDY
LTAAPRGRYSERELPYYLG--PHPVHPPRGGYPHSSD-LRVADLRYPQYYPRPPA-QQHK
GPFRQDVPPSPPQHQRVTTYQEVGRARPRGGSPERNPYRNQDPRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MSDVQAELLSSPKAKAALS--EVTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSQKEGLFNENECIVKINSVDLVDKTFAQAQDIFRQAMKSPNVLLHVLPPPN
REQYEKSVIGPLNIFGNNDGIL-RTKV-PPPVHGKSGIKTENLTGTSSPDVGAATSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

V
ARQEGSFLPRELKGEPD-CYALSQETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPEKTMEEPA--ECGVFSKPCVENCQNSVT-ISRRNGSSTLQPFGMYSPQDKQKE
LLL--LNDGWAESEVPPSP-PPHPGLELGLEDYSHSSGVDSAVYFTDQHVNFRSVT-PAR
QPEPINLKASKSMDLVPDES--KVHSL---AGHKSESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
SCESAPQGNSELEDLENKTRKVKKKKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKDDKGGKAEQKGAP--KHGELREEELEKMKE-RERIGAKHQEL
REK-QVRGLVDYATGGMGSLHDMDDDE--MDPNY---ARVNHFREPCASASVYRSPSPPR
AGLLSYPRDGHPLSPERDHLEGLYAKVNKSYHPPAPVDSGRPTSGSADRIQKLRKEYYQA
RREGFPLYEDDEGRARPSDYDLHWAVNSQLF---FKWSWKSETSKMNS------------
LLLQRKDLCKM-------------------------------------------------
-----------------------------------------------------

-----CFGRTGIV-VCKEGQLRVRELTQQALQRYLKTREKDPGYWMKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLHKIE--SPGGNPAGRQSPDAFEMEVAAQLAVFKPV
G--GEIEVTPSALKLGTPLLVRRSSDPAPSPPADAQPSASHPSGQSLKPVMPNSTQ-DLE
DGEVMNGAQTEILTSPKTMDGLS--DMTRTVELSGEGGPLGIHVVPFFSSLSGXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQDVFRQGMKSPRVLLHVLPPQN
REQYEKSVIGPLNIFGND-GVL--RKVPPPVH-GKSGIKKVNLADSGPED--TSTSLHXX
XXXXXXXXXXXXXXXXSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGTFLPRELKGEPD-CCALSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPVEEQA--ECGALSKPCFENCQNATT-TSRRNDNSAPHPLGTYSPQDRPKE
LLL--PNDRWAESKAPPSP-PPNPVLELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVHSLAGHKSXXXXXXXXXXXXXXXXX---XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXGLSDKSSHSDQGAL
NCESAPQGNAELENVENKARKGKKTKEKEKK-------KEKGKLKGKEKKQKEGNEDPER
KIK-RKGLGAMLRFGKKKDDKGGKAEQKGPL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLIDYATGAMGSLHDMDDDE--MDPNY---ARVNHFREPCASANAYRSPSPPR
PGPLGYPRDGRPLSPERDHLEGLYAKVKKPYHPPVPADSGRPMSGSADRIQKLRKEYYQA
RREGFTLYEDDDGRARA-DYDLHWVSGKGPDGNAHNLRFEGMERQYASLP----------
------------------------------------------------------------
-----------------------------------------------------

--------------------------------------------MIALS---------Q-
PHGQE---LC

PF12053 // ENSGT00760000119017_2_Domain_0 (71, 147)

DTSQLIAVFDEQEPLHKIE--SPSGNPADRQSPDALETEVAAQLAAFKPI
G--GEIEVTPSTLKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPRASHLDGQSMRPVVSDSTQ-NLE
DREVMNGVQTELLMSPQMKDALS--DMTRTVEISGEGSPLGIHVVPFFSSLSGRILGLFI
RGIEGNS-RCKREGLFQENECIVKINNVDLADKTFAQAQDIFRQAMKSTNVLLHVLSPQN
REQYEKSVIGPLNIFGN-DGIL-RTKV-PPPVHGKLGLKTVNLTGTNSPEAEPSTFLQQS
KS-PRVPRLGRKPSSPSLSPLLGFGNKKSAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGRDVTGKTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKARETGTDL
GIFIKSVIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPTEETA--ECGAFSKPCFENCQNALT-TSSRNESGILQSFDNYSPQDKQKD
LML--PHDEWAECELLPSL-PPHPSLELGLEDYSHSSGVDSAVYFPDEHINFRSVT-PAR
QPESINLKASKSMDLVADES--KLHSL---AGPRPESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNERPFHRPWPHVIRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKTRKAKKTKEKEKKK-------EKGKLKIKEKKQKEENEDPER
KIK-RKGFGAMLRFGKKKDAKSSKAEQKSAPP-KQGSLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGTIGSVHDMDDDE--MDPNY---ARVNHFREPCVSANVFRSPSPPR
TGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPPTPVDSGRPAGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRTRPSDYDLHWVSGKSTDGNAHNLRFEGMERQYASLPRGGPADPLDY
LTSAPRGLYKERELPYYPG--AHPVHPPKGGYACPPD-LRLTDLRYPQYYSPPAV-PHHK
GPFRHDVPPSPPQHQRVLAYQEMGRAGPRGGSPDRHPYRTQDPRQKNPMTAAV

------------------------------------------------------------
------CTDTVYMYLIAVFEEQEPLHKIE--SPSGNPTDRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADAQPSGSHPGGQSLKPVVPDSMQ-NLE
DREVMNGVQTELQTSPKIKDALS--NMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVVLHVLPPQN
REQYEKSVIGPLHVFGSNDGVL-KTKVPPPIH-IKSGLKTVNLPGTNSPETDASTSLQQN
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CYALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPFGTYSPQDKQKD
LLL--PTDGWAESEVPPSP-PPHPGLELGLEDYSHSSGVDSAVFFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AEHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEFE-ADGLSDKSSHSGHGAL
NCESAPQGNSELQDMENKARKVKKTKEKEKK-------KEKGKLKVKEKKRKEENEDPER
KMK-KKGFGGPALTAKL-----GLL--FLFV--SSGAITPFCVLRKKCKSSLFSA-----
------NGIK---TETMNTSWMVAVGDG-SSLTYCCSMCLAHWKYCCLAR----PNAPPV
MQVQLVPAVPLPPPPA---LETLHPALHLQTSPG--------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKPVVPDSTQ-NLE
DREVLNGVQTELLTSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSASVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGVL-KTKV-PPPVHGKSGLKTANLTGTDSPETDASASLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 475)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGE

ENSGT00760000119017_2_Linker_1_2 (475, 518)

IASLVI
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENSQNAVT-TSRRNDNSILHALGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGQKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLVPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

------------------------------------------------------------
------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (79, 147)

FDEQEPMHKID--NSGGNLSDRPSPDALETEVATQLAAFQPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PVPCPPADSLPAAHLN-DSNGKPL-VSSAQ-NLD
DEEVVFAGQTEVVISPKSKYTFS--DLTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKRDGLLYENECIVKINNVELVDKTFAQAQDVFRRAMKAPNVLLQVLPSQN
RDQYEKSVIAPLCIFVNDNGIS-KTVM-SPPVQPAG--RMADLNGTSNMETAASSSLQQS
KS-PRVPRVGRKPPSPSLSPLMGLRSRKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRESSVHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDIMGRTQEELVAMLRSTKQGEIVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEESFLPRELKGEPD-CWALSLEATEQLTFEVPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGADL
GIFIKSIIHGGAAFKDGRLRTNDQLIAVNSESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVVLRRMERQIEEYP--ELRTFQKAAGENCQNFATT--SRHSDVTPQTVVAYSPQDKQKG
EYF--EQDLLPSFISPPSPTA--RMYIIFCMTSFHSSVVDPTVYFTDQHINFRSLA-PAK
QPESINLKASKSMDLVPDES--KVLSL---VGHRSESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEDLE-ADALSDKSSHSGQETL
NCSSVPQGNTELE---AKAKKNKKYKEKEKKK-------EKSKSKVKEKKRKEENEDPEK
KAK-KKGFGAMLRFGKKKEDKGGKAEQKGGP--KHGSLREDELEKMKEERER--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD
PDDILADVVEDKDKLIAVFDEQEPLQKIE--SPSGNPVDRQSPDAFETEVAAQLAAFKPI
S--GEIIVTPSSLKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSAASPSGQSLKPVVPNSTQ-NLE
NREVMNGEQTELLTSHGTKDALS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQN
REQYEKAVIGPLNIFGNSDGAS-RTKV-PPPTRGKPGLKAVTLTGTNSPEADESTSPQQS
KS-PRVPRIGRKASSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVLMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQDGSFLPRELKGEPD-CYTLSLETSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 589)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVIIRRLERPLEELT--ECGALSRPCFENCQEALS-PSRRNDSSASYPFGTYSPQDKRKD
LLL--PNDGWAESEVSPSP-PPHPGLEWALEDYSHS-----PVYFPDQHVNFKSVI-PAM
QPESINLKISKSMDLVPDES--KARSL---ADRRLDSPSNDFGPTLGLKKSSSLESLQTA
VAEVRKSDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEVE-ADGLSDKSSHSGHGAL
NCESIPQGNPELDDVENKARKVKKAKEKEKKK-------GKGKLKVKEKKQKEESEDPEK
KMK-RKGFGAMLRFGKKKDDKGGKVEQKGTQ--KPGNLGEEELEKMKEEKERIGSKHQEL
REK-QARGLLDYATGGIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPLAYPRDGRPLSPDRDHLEGLYAKVNKPYHPPALAD----------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

----------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (41, 83)

DPSYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPPHKTE--SPGGSAADWQSSEALETEV----ATFKPI
G--GEIEVTPSTLKLGTPLLVRRSSDPAPGPPADAQPRVAHPSGQSVKPVVSDSTQ-NLE
DREVMNGIQTELLTSPKMKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVDLVDKTFAQAQDIFRQAMKSPNVLLHVLSPHN
RDQYEKSVIGPLNIFGNNDGVL-RTKV-PPPAHGKSGLKTVNLPGTNSPEADPSTSLQQS
KS-PRVPRVGRKPSSPSLSPLMGLGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGDTASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKARETGMDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRLERPIEEIA--ECGAFSKPCFENCQNVLT-TSSRNETSTLHSFDNYSPQDKQKD
LVL--PHDEWAKCEVPPSP-PPRSGLELDLEDYSHSSGVDSAVYFPDQHINFRPMT-PAR
QSESINLKASKSMDLVPDES--KVQSL---AGPRPESPNKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSHSGQGAL
NCESAPQGHAELEDMENKARKVKKIKEKEKKK-------EKGKLKVKEKKQKEENEDPER
KIK-RKGLGAMLRFGKKKDGKRVEADPKGG-P-KQGNSQEEELEKWKGTRERIGAKHQEL
REK-QARGLLDYATGTIGSMHDMDDDE--ADPNY---ARVNHFREPCASANVFRSPSPPR
TAPFGYPRDGRPLSPERDHLEGLYAKVNKSYHPPAPVDSGRP--GNSDRIQKLRKEYYQA
RREGFPLYEDDAGRSRPSDYELHWVSGKSPDGNAHNLRFEGMERQYASLPRAGPADPVDY
LTAVPRGLYKERELPYYPG--AHPAHPPKGGYVRPPD-LRVTDLRYPQYYPPPPL-PQHK
GPFRQDVPPSPPRQQRVPAYQEMGRAGPQGGSPDRPAYRTQDPRQKNPMTAAV

MKVTVCFGRICIVVPCKEGQLRVRELTQQALQRYLKTREKXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLIAVFDEQEPLHKIE--SPSGNLADRQSPDAFETEVAAQLAAFKPI
G--GEIEVSPSALKSGTPLLVRRSSDPASGPPADIQPSASHPSGQSLQPVVSDSSQ-NLE
DGEVMNGVQTEVLASPKTKDALS--DLTRTAEISGEAGPLGIHVVPFFSSLSGXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQEVFRQAMKSPRVLLHVLSPQN
REEYEKSVIGPLNIFGNNDGIL-RTKTPLPVH-GKSVIKTVNLTGTSSPETDASAALQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGNFLPRELKGEPN-CYGLSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 555)

EIPLNDSGSAGLGVSLKGNKSRETGTDL
GIFIKSVIHGGAAFKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXEPT--EYGTFSKPGFENCQNTIT-TSRRNDNSTPHPFGTCNPQDKWKE
LLL--SNDGWTESEVPPSP-PPHPDLELGLEDYS--SGMDSAVCFPDQHINFRSLT-PAR
QPESINLKASKSMDLVPDES--NIHS----AGHKSESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSYSGQGAQ
NCESAPQGSSELEDVENKARKVKKSKEKEKK-------KEKGKLKAKEKKRKEENEDPER
KIK-RKGFGAMLRFGKKKEHKGGKAEQKGTL--KRGGLREEDLEKMKDERERIGAKHQEL
REK-QARALVDYSAGAIGSLHDMDDDE--MDPNY---ARVNHFREPCTPASIYRSPSPPR
PGPLGYPRDSHPLSPERDHLEGLYAKVNKPYHPPAPADXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXVPGKGPDGSAHNLRLEGLERQYASLPRGGPMDPVDY
MTAGPRGIYKERELPYYPE--VRPVHPPKGGYPRLPD-LRVTDLRYPQYYLSPPA-PQHK
GPFRQDVPPSPPLHHRAPAYQEMGRPGLRGGSADQYPYRTQDPQQKNPMTAAV

-------------------------------------------MAVQLS---------TI
KTKVTICTLKTCIL

PF12053 // ENSGT00760000119017_2_Domain_0 (75, 147)

LIAVFDEQEPLHKIE--SPSGNPTDRQSPDALETEVAAQLAAFKPI
G--GEIEVTPSTLKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPRASHLDGQSMRPVVSDSTQ-NLE
DREVMNGVQTELLMSPQMKDALS--DMTRTVEISGEGSPLGIHVVPFFSSLSGRILGLFI
RGIEGNS-RCKREGLFQENECIVKINNVDLADKTFAQAQDIFRQAMKSTNVLLHVLSPQN
REQYEKSVIGPLNIFGN-DGIL-RTKV-PPPVHGKLGLKTVNLTGTNSPEAEPSTFLQQS
KS-PRVPRLGRKPSSPSLSPLLGFGNKKSAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGRDVTGKTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKARETGTDL
GIFIKSVIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPTEETA--ECGAFSKPCFENCQNALT-TSSRNESGILQSFDNYSPQDKQKD
LML--PHDEWAECELLPSL-PPHPSLELGLEDYSHSSGVDSAVYFPDEHINFRSVT-PAR
QPESINLKASKSMDLGKQ---------------EGESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNERPFHRPWPHVIRGRGCNESFRAAIDKSYDGPEELD-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKTRKAKKTKEKEKKK-------EKGKLKIKEKKQKEENEDPER
KIK-RKGFGAMLRYRPALKAKL--------------------------------VLERKL
REK-QARGLLDYATGTIGSVHDMDDDE--MDPNY---ARVNHFREPCVSANVFRSPSPPR
TGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPPTPVDSGRPAGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRTRPSDYDLHWVSGKSTDGNAHNLRFEGMERQYASLPRGGPADPLDY
LTSAPRGLYKERELPYYPG--AHPVHPPKGGYACPPD-LRLTDLRYPQYYSPPAV-PHHK
GPFRHDVPPSPPQHQRVLAYQEMGRAGPRGGSPDRHPYRTQDPRQKNPMTAAV

MKVTVCFGRTGIVVPCKEGQLCVRELTQQALQRYLKTREKDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLHKIE--SPSGNPASRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKPVILDSTQ-NLE
DGEVMNGVQTEVLTSPRVKDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAHAQDVFRQAMKAPSVLLHVLPPQN
REQYEKSVIGPLNIFSNNDSVL-RTKPPPSVH-GKSGIKTINLTGTSSPEEDASTSLQQS
KS-PRVPRLGRKPPSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGTFLPRELKGEPD-CYALSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRVRMNDQGIAANGESLWGKSSQEGREPIR-RMSMEGNIRGMIQ
MVILRRPERPMEEPA--EYGAFSKSCFENCQNAVT-TSRKNDNSTLHPFGTYSPQDKQRE
PLL--PSDEWAESEVPPSP-PPHPILELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVHSL---AGHKLESPGKGFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
NCESVPQGNSELEDIENKARKVKKTKEKEKK-------KEKGKLKVKEKKQKEENEDPER
KIK-RKGFGAMLXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXIGAKHQEL
REK-QARALVDYATGTIGSLHDMDDDE--MDPNY---ARVNHFREPCASANVYRSPSPPR
AGPLGYPRDGRPLSPERDHLESLYAKVNKPYHPPVPADSGRPMSGSADRIQRLRKEYYQA
RREGFALYEDDEGRARPSDYDLHWVSGKGPDGNTHNLRFEGMERQYASLPRGGPADPVDY
LTAAPRGLYKERELPYYPG--AHPVHLPKGSYPRPPD-LRVADLRYPQYYPPPPT-PQHK
GPFRQDVPPSPPQHHRVPAYQEMGRAGPRGGSPDQYPYRTQDPRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------ILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPGVVLHVLPPQN
REQYEKSVIGPLNIFGNSDGVL-KTKV-PPPVHVKSGLKTVNLTGTNSPEADASNSLQQN
KS-PRIPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGQTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGNFLPRELKGEPD-CYALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPFGTYSPQDKQKD
LLL--PTDGWAESEVPPSPPPPHPGLELGLEDYSHSSGVDSAVFFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKLESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGHGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENDDPER
KMK-KKGFGAMLRFGKKKEDKGEKSEQKATL--KRGGLREEELERMKEERERIGAKHQEL
REKQ--ARGLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYRLPAPVDSVRPAAGSTDRIQKLRKEYYQA
RREGFPFYEDDEGRARPSDYDLLWVSGKGPDGNAHNLRPEGMERQYASLPRAGPADPAAY
LTAAARGLYTERELPYYPG--AHPVHPPKGSYPRPPD-LRVADLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHQRVPAYQESGRPGPRGGSPDRYPYRPQDPRQKNPMTAAV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MNGMQTELLTSPKTMDALS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDLFRQAMKSPSVLLRVLPPQN
REQYEKAVIGPLNIFGNNDRML-RTKE-PPPVQGKSGIKTINLTGTSSPEEDASTSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGTFLPRELKGEPD-CCAFSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEEPA--ECGAFSKPCFENCQNAVS-TSRRNDNSTLHPFGMYSPQDKQKD
LVL--PNDGWAESEVPPSP-QPHPVLELGLEDYSHSSGVDSAVYFPDQHINFRSMT-PAR
QPESMNLKASKSMDLVPDES--KVHSL---AGHKSDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDRSSHSGQGAL
NCESAPQGNSELENAENKARKVKKTKDKEKKK-------EKGKLKVKEKKQKEGNEDPER
KIK-KKGFGAMLRFGKKKDDKGGKAEQKGPL--KQSGLREEELEKMKEERERIGAKHQEL
REK-QARSLIDYATGAIGSLHDMDDDE--VDPNY---ARVNHFREPCTSANVYRSPSPPR
AGPLGYPRDGRPLSPERDQLESLYAKVNKPYHPPVPADSSRSMSGSADRIQKLRKEYYQA
RREGFALYEDDEGRARP-DYDLHWVSGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LTAASRGLYKERELPYYPG--AHPVHPPKGSYPRPPD-LRVTDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRVPAYPEMGRPGPRGSSPDQYPYRTQDPRQKNPMTAAV

MKVTVCFGRTGIVVPCKEGQLHVRELTQQALQRYLKTREKDPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLHKIE--SPSGNPAGRQSPDAFETEVAAQLAAFKPV
G--GEIEVTPSALKLGTPLLVRRSSDPAPSPPADARPSASHPSGQSLKPVIPNSTQ-DLE
D-EVMNGVQTELLTSLKTVDALS--NMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVTGPLNIFGNNDGVL-RTKVPPPVH-GKSGIKTVNLTGTSSPEEDASTSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVI

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEGTFLPRELKGEPD-CYALSLETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLQVNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPGRPLEEPA--ECGAFSKPCFENCQNAVS-TSRRNDNSTLHPFGTYSPQNKQKE
LLL--PNDGWAESGGPP-P-PPHPVLELGLEDYSHSSGVDSAVFFPDQRLNFRSVT-PAR
QPESMNLKASKSMDLVPDES--KVHSL---AGHKSDSPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
NYESAPQGNSELENAENKARKVKKPKEKEKK-------KEKGKFKVKVKKQKEGNEDPER
KIK-RKGFGAMLRFGKKKDDKGGKAEQKGPL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLIDYAAGAIGSLHDMDDDE--MDPNY---ARVNHFREPCASANVYRSPSPPR
AGPLGYPRDGRPLSPERDHLEGLYAKINKPYQPPVPADSGRSISGSTDRIQKLRKEYYQA
RREAFALCEDSEGRARP-DYDLHWXXXXXXXXXXXXXXXXXXXXXXXXXXXGGPADPVDY
LTAAPRGLYKERELPYYPG--AHPVHPPKGSYPRPPD-LRITDLRYPQYYPPPPA-PQHK
GPFRQDVPPSPPQHHRVPAYPEMGRPVPRGGSPDQYPYRMQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPGASHPGGQSLKPVVSDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-LPPVHGKSGLKTANLTGAESPETDASTCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNNTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKCKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADAVDY
LPAAPRGLYKERELPYYPG--AHPMHPAKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRPQDSRQKNPMTAAV

------------------------------------------------------------
--------------LIAVYDEEEPHRKTD--GTNGSVADRSSPDPFEAEVAAQLAAFQPI
G--GEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHPSDHSLKHVTAGASQRSFE
DGEMNLSGPTEVLSSQRTRLPVS--EMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFI
RGIEENS-RSRRDGLFHENECIVKINHVDLIDKTFAQAQDIFRQAMKFQSVILEVLPPYN
REQYEKSAIAPLCFLHNEEEVP-KTKI-PPPVHPKPALKPVNLSGPGSLEAGVQSTLQQA
KS-PNLPRLSRKSSSPSLSPLMGFGNKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 481)

KIDLKKDVLGPEGLGFTVVTRESSVHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQEELVAMLRSTKQGETVCLIV

ENSGT00760000119017_2_Linker_1_2 (481, 513)

ARQEEAFLPRELKGEPN-CSVLSPETTEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGADL
GIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQ
LVVLRRLEAQTEDRL--DQGAFKKSAFDGSHNFAAV--SRRNDTILQQFVTCSPQERIQE
--LPVSDHGSGENETPPPL-PPHPTEDLLNEDYNHSPITNSAMYLTDQHINFRSLT-PAK
QSESINLKASKSMDLVADES--KVGSL---AGCKSDSSSKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDTE-EDGFSDKSSHSGQEAQ
NMESAPPGNPEIEDVETKLKRKQ-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPV
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPVASHPGGQSLKPVVPDSTQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNSDGIL-KTKA-PPPVHGKSGLKTANLTGAESPETDASTSLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQDGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGAYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKENKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDNEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

MKVTVCFGRMGIVVPCKDGQLRVRDLTQQALQRYLKAKEKXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXLIAVFDEQELVPKVE--SPSGNLTESHSPDPFDAEVATQLATFKPI
G--GEIEVTTSALKLGTPLLVRRSSDPALGPPADSHPGALHPSDQNLKPVVPXXXX-XXX
XXXXXXXXXXX--XXXXXXXXXXXXDMTRTVEISGXXXXXXXXXXXXXXXXXXXILGLFI
RGIEENS-RSKRDGLFHENECIIKINNVDLIDKTFAQAQDVFRQAMKSQNVLLQVLPPNN
REQYEKSVIAPLGIFGNSDVVW-RTKV-SPPIQGRPALKTINLTGPSVLETETEISSQQN
RS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKI

PF00595 // ENSGT00760000119017_2_Domain_1 (394, 449)

KIDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRIL

ENSGT00760000119017_2_Linker_1_2 (449, 513)

EXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXKGEPDHCYVLSLETPEQLTF

PF00595 // ENSGT00760000119017_2_Domain_2 (513, 604)

EIPLNDSGSAGLGVSLKGNKSRETGADL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRMDRQTEERT--DYGLFPKPSLESCQHFVTP--SRRHEPSPHPFLTYSPQERQKE
PLL--TDTNWTESDIPPPL-PPHPSLELDLEEYNHXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXPDES--KVHSL---AGQKLEPTGKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEDLE-EDGMSDKSSHSGQGAL
NCESNPQGNPAPVDIENKAKN-KKKKDKEKKK-------EKGKLKDKEKKRKEENEDPEK
KVK-KKGFGAMLRFGKKKEDKGGKNEQKGNL--KQGTLQEEELEKMKEEREXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX---XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXVSGKSPDGSTHNLRFEGMERQCASLPRRGPTEPADY
LT-GPRLIYKEREPPYYPG--MQPFHPPKGSYPRAQD-VRVPDLRYPQYYPPLPA-THHK
GPFRQDVPPSPPQRHKVPAYHEIGKTGQRAASPEQYPYRAQDPRQKNPMTAAM

------------------------------------------------------------
--------------

PF12053 // ENSGT00760000119017_2_Domain_0 (75, 147)

LIAVFDEQEPLHKIE--SPSGNPTDPQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PVPGPPADTQPSASHPGGQSLKPIVSDSMQ-NLE
DGEIMNGTQTELLTSPKPKDALS--DMTRRVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKREGLFHENECIVKINSVDLVDKTFAQAQDIFRQAMNSSSVLLHVLPPQN
REQYEKSVIGPLSIFGNSNGAL-RTKVAPPVH-GKPGLKTVNLPGMNSPEADTSASLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GSEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGKDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CYALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 588)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGEALLGKSNHEAMETLRRSMSMEGNIRGMTQ
LVILRRPEKQMEEFA--ECGALPKPCFENCQNALS-PSRRNDGSLLHPFGTYSLQDKQKD
LLL--PSDGWAESEEPPSL-PPHPGLELGLEDYSHSSGVDSAAYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVYSLAGLAGHRSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSQSGQGAL
NCEPALQRSSELEDVENKTRKVKKTKEKEKK-------KDKGKMKVKGKKQKEENEDSER
KMK-RKGLGAMLSLKSVFRERAVL----------HRAVQCQWP--LYQIAPRYVHLHS--
------------EGGRPGTPHSLPGTPSLSTPVSECANGPTLWAQ---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPAERQSPDAFETEVASQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPGASHPGGQSLKPVVSESMQ-NLE
EREVMNGVQTEL-TSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGPLNIFGNNDGVL-KTKA-PPPVHGKSGLKTANLTGAESPETDASTCLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKEEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPEKPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWTESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFSAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLAPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDSEGRARPSEYDLLWVPGKGPDGNAHNLRFDGMERQYASLPRGGPADAVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKPVVPDSTQ-NLE
DREVLNGVQTELLTSSKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQN
REQYEKSVIGSLNIFGNNDGVL-KTKV-LPPVHGKSGLKTANLTGTDSPETDASASLQQN
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILSKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETSEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPMEDPA--ECGAFSKPCFENCQNAVT-TSRRNDNSILHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-TPHSALELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVPDES--KVHSL---AGQKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRSRPHMVRGRGCNESFRAAIDKSYDGPEEIE-ADGLSDKSSHSGQGAL
NCESAPQGNSELEDMENKARKVKKTKEKEKKK-------EKGKLKVKEKKRKEENEDPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGTL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVYDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPADSGRPTGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRARPSEYDLLWVPGKGPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LPAAPRGLYKERELPYYPG--AHPMHPPKGSYPRPTE-LRVADLRYPQHYPPPPA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 147)

MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYRDGGILD
PDDVLADVVEDKDKLIAVFDEQEPLQKIE--SPGGNPVDRQSPDAFETEVAAQLAAFKPV
G--GEIVVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPHADAQPSTASLSGQSLKPVVLDSAQ-NVE
NKEVMNGEQAGLLSLHRTRDELS--DMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQN
REQYEKSVIGPLNIFGNNDGAS-RTKA-PPPARGKPGLKAVHLTRASSPEGEESASPQQS
KS-PRVPRLGRKPSSPPLSPLLGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGSFLPRELKGEPD-CCALSLESSEQLTLEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPLEELS--ECGALSRPGFENCQEALS-TSRRNDSSILYPFGTYSPQDKRKD
LLL--PSDGWAENEVPPSP-PPHPALEWGLEDFSHSSGVDSTGYFPDQHANFRMVT-PVR
QPELINLKASKSMDLVPDEG--KVQSL---ADRRSDSPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAD-ADGLSDKSSRSGHTTL
NCESAPQGNPELDNVENKAKNIKKTKEKEKKK-------GKGKLKVKEKKLKEEREDAER
KMK-RKGFGAMLRFGKKKDDKAGKAEQKGTQ--KSGHPEEEELERMKEERERIGAKHQEL
REK-QARGLVDYATAVTGPMHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPLR
AGPLAYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQA
RREGFLLYEDENTRARPSDHDLRWVSGKGPDGSAHNLRFEGMERQYASLPRGGSADPVDY
MTASPRGRYNDRELPYYPG--PHPVHAPRGSYPRPPD-LRATDLRYPQYYPPPPA-HQHK
GPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKNPMTAAV

PF12053 // ENSGT00760000119017_2_Domain_0 (1, 83)

MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKNREKGPGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDAFETEVAAQLAAFKPI
G--GEIEVTPSALKLGTPLLVRRSSDPVPGPPADAQPSTSHPGGQVLKPVIPDSTE-NLE
GREVMNGEHTELVTSPKTKDTLS--DMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMRSPSVFLHVLPPQN
REQYEKSVIGPLNIFGNSDGIL-KTKM-PPPVHGKSGIRTANLTRTDAPETDTSASLQQS
KS-PRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
ARQEGHFLPRELKGEPD-CCALSLETTEQLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNNEAMETLRRSMSMEGNIRGMIQ
LVILRRPERPVEDPA--ECGAFSKACFENCQNAVT-TSRRNDNSTLHPLGTYSPQDKQKD
LLL--PNDGWAESEVPPSP-APHSTLELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
EPESINLKASKSMDLVPDES--KVHSL---AGHKSESPSKDFGPTLGLKKSSSLESLQTA
VAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEELE-ADGLSDKSSHSGQGAL
NCESTPQGNSELEDVENKARKVKKAKEKEKKK-------EKGKLKVKEKKRKEENENPER
KIK-KKGFGAMLRFGKKKEDKGGKAEQKGAL--KHGGLREEELEKMKEERERIGAKHQEL
REK-QARGLLDYATGAIGSVHDMDDDE--MDPNY---ARVNHFREPCTSANVFRSPSPPR
AGPFGYPRDGRPLSPERDHLEGLYAKVNKPYHPLGPVDSGRPTGGSTDRIQKLRKEYYQA
RREGFSLYEDDEGRARPSDYDLLWVSGKGPDGNAHSLRFEGMERQYASLPRGGPTDPVDY
LPAAPRGIYKERELPYYPG--SHPMHPPKGSYPRPAE-LRVADLQYPQHYPPPTA-PQHK
GPFRQDVPPSPPQHQRMPAYQETGRPGPRAGSPDRYPYRTQDSRQKNPMTAAV

----------------------------------------D

PF12053 // ENSGT00760000119017_2_Domain_0 (42, 147)

PGYWVKIHHLEYTDGGILD
PDDVLADVVEDKDKLIAVFEEQEPLHKIE--SPSGNPADRQSPDALETEVAAQLAAFRPI
G--GEIEVTPSALKLGTPLLVRRSSD

ENSGT00760000119017_2_Linker_0_1 (147, 395)

PAPGPPADAQPRASYPDGQSVRPVVSDSTP-NLE
DREVMSSVPTELLTSPTTKDALS--DMTRTVEISGARGPLGIHVVPFFSSLSGRILGLFI
RGIEENS-RCKREGLFQENECIVKINNVDLTDKSFAQAQDVFRQAMKSPHVLLHVLSPQN
REQYEKSVIGPLNIFGNNDGIL-RTKV-SPPVHGKLGLKTVNLTGTNNPEAETSTSLQQS
KS-PRVPRLGRKPSSPSLSPLMGFGSKKNVKKIK

PF00595 // ENSGT00760000119017_2_Domain_1 (395, 480)

IDLKK---GPEGLGFTVVTRDSSIHG
PGPIFVKNILPKGAAIRDGRLQSGDRILEVNGKDITGRTQEELVAMLRSTKQGETASLV

ENSGT00760000119017_2_Linker_1_2 (480, 518)

I
VRQEGSFLPRELKGEPD-CYALSLEMSEKLTFEIPLN

PF00595 // ENSGT00760000119017_2_Domain_2 (518, 590)

DSGSAGLGVSLKGNKSRETGTDL
GIFIKSVIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMQTLRRSMSMEGNIRGMIQ
LVILRRPERPTEEAP--ECGAFSKPCFENCQNALT-TFSRNESGILQSFDSYSLQDKQKD
LVL--PRDEWGECEVLPSL-PPHPTLELGLEDYSHSSGVDSAVYFPDQHINFRSVT-PAR
QPESINLKASKSMDLVADES--KLHSL---AGPRPESPGKDFGPTLGLKKSSSLESLQTA
VAEVRKNELPFHRPWPHVIRGRGCNESFRAAIDKSYDGPEELD-ADGLSEKSSHSGQGAL
NCEYAPQGNSELEDLENKTRKAKKLKDKEKKK-------EKGKLKFKDKKQKEENEDPER
KIK-RKGFGAMLRFGKKKDAKSGKAEQKTAPP-KQGNLREEELEKMKEEQERIGAKHQEL
REK-QARSLLDYATATIGSVHDMDDDE--MDPNY---ARVNHFREPCASANVFRSPSPPR
TGPFGYPRDDRPLSPERDHLEGLYAKVNKPYNPPAPVDSGRPSGGSTDRIQKLRKEYYQA
RREGFPLYEDDEGRSRPSDFDLHWVSGKSPDGNAHNLRFEGMERQYASLPRGGPADPVDY
LTAAPRGLYKERELPYYPG--AHPAHPSKGGYACPPD-LRVTDLRYPQYYPPPPV-PQHK
GPFRQDVPPSPPQHQRVLAYQEMGRAGPRGGSPDQHPYRTQDPRQKNPMTAAV