Query Results 

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLILIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLSLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLEHFIIFSQRRGAQNVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQQFIRRPSVQDLLWVTRPLIQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDTTRKDPIYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYAPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAETILNFLYKGP
RESQADDMANFDWRDVFNVTDRTLRLVNQYLECLVLDKFENYDDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKENLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLS
MQMMLLDAAIYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PVTEEMEDPE--------------------------------------------------
------------------HPGGTHDSFFEREHPGWVPGVCVKNLVKTFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGRDIETSLNAIRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1789)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRRGSEGTC-SCASKGFSTT
TCSAHVSDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPSKNFKQRAYA
SLFRE-LEETLADLGLSSFGVSDTPLEEVN------------------------------
---GLWTLKIENVNLRHPCLGLRENTGQIPQDSNDCSPGALAAHPEGQPPPEPE-CPGPQ
LNTGARLVFQHVQALLLKRLQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGHQYTFFSMDEPSSEQLAVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNVTQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GVSIGGKLPAIPITGETLVGFLSDLGRIMNVSGGPVTREASKEIPAFL

PF12698 // ENSGT00760000118965_5_Domain_2 (1789, 2078)

KHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYTV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRMLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YTRFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2151)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRVITGGNKTDILRLHELTKIYPGTSSPAVDR

PF00005 // ENSGT00760000118965_5_Domain_3 (2151, 2292)

LCIGVRAGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYFYARLRGVPAEEIEKVANWSIKSLGLTIYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPRDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQVPLLLLQ-----------------STARGIS----
----------------------------

-------------------------------------MGFVKQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLILIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGVFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLSLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLEHFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-RSQGVNLRSWGGILSDMSPRIQQFIRRPSVQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDTTRKDPIYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANFDWRDIFNVTDRTLRLVNQYLECLVLDKFENYDDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKENLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTTELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLS
MQMMLLDAAIYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLVQESYWLGSEGCSTREERALEKTE
PLTEEMEHPE--------------------------------------------------
------------------HLGGIHDSFFEREHPGWVPGVCVKNLVKTFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGRDIETSLNAIRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1789)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRRGSEGTC-SCASKGFSTT
TCSAHVSDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPSKNFKQRAYA
SLFRE-LEETLADLGLSSFGVSDTPLEEIFLKVTEDSGSGP-------------------
LFAGGTQQKRENVNLRHPCLGPRENTGQIPQDSNNCSPAALAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLLKRLQHTIRSHKDFLAQIILPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGHQYTFFSMDEPSSEQLTVLADVLLSKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNVTQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGQIMNVSGGPVTREASKEIPAFL

PF12698 // ENSGT00760000118965_5_Domain_2 (1789, 2077)

KHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYTI
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNQMLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YTRFGEKHSANPFHWDLIGKNLFAMVVEGVVYFLLT

ENSGT00760000118965_5_Linker_2_3 (2077, 2150)

LMVQRHFFLSQWI--AEPTKEPI-
-------ADEDDDVAEERQRVITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRAGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYFYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQVPLLLLQ-----------------STA--------
----------------------------

-------------------------------------MGFLRQ-IRLLLWKNWILRKRQK
LRILVELIWPLSLFLALVWLRKANPLYRQHECHFPNKAMPSAGTLPWLQGIFCNMNNPCF
RNPTRGESPGVVSNYNNSI-----------LARVYKDAQELLLEAPEIHDLGRVWEELII
MTQFMETMRTNPERIAGRGIRILDILKDGETLTSFLLENLGLPDAVVFQLVNAQ-VRPEQ
FAYGVPNLTLKDIACSQMLLDRFIIFSSRRGLPSVHKAMCALSQEGLQRVEDALYANVDL
FKLFQLLPTVLDR-NSPGADLRSWGRVLSNVSQAVQKLARKQSVQDLLMVWEPFVQGGIP
ESLDHLVSSLSDLFCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTK-KSIYLYD-NTTTP
FCNELIQNLESNPLTKIAWSAVKPLLMGKILFAPNSPPVQQ-IIKNANSTFEELGRLRLL
IKAWEEVGPQLWYFFQNSLQMNMIRDSLKHSTVRDFLNSQLGTEGL-TAEYIINFLHNGP
PGSREKGMVDFDWRNIFSAADQALRLLSQYLECLTLDKFEGYHDETQLTHQA-LHLLEEN
KFWAGVVFLDI-DPTRKTLLPHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDLRYI
WGGFAYLQDMIEHGIIKTQTNTEVPQGIYLQQMPYPCFVDDV-FMITLNRSFPIFMVLAW
IYSVSMTVKSIVLEKEKRLKEAMKNRGITNGVIWCTWFLDSFFMMAVSTFLLTALIMHGQ
VLHYSSPLLFFLFLLTFNTATIMQCFLFSTFFSKANLAAACSGVLYFTLYLPHIVCFVWQ
DRMTVNLKIL----ASFLSQVAFGFGTEYLSRYEEQGLGLQWGNIRTSPLEGDEYSFLFS
IKMMLFDAFLYGILSWYL-DHVFPGDYGLPQPWYFPLQESYWEGGEKA------------
SESEGCVDQKAMDGERNGSRT---KKSEESEKP---------------------------
----------------------EGNTFCEPEPTGLIPGVCIQNLVKIFANKPKPAIDRMN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

GQITAFLGHNGAGKTTTMPILH--YHPTTGYLMICSLTAISLWSSQQQPFFLNAA
ARVRFHSLTVAEHILFYSQLKGRSRDEAEQELEMMLEDMGLSHKRNEEAQNLS--GGMQR
KLSVAIAFVGEAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIILSTHHMDEADILGD
RIAIISQGKIFCSGSPVFLKNCFGSGFYLTLVRKVKNTRTGRS-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELHI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLISSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKEPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELDRVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLMQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSREEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVNDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKAGQTPRDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLMVLADVLLNKPGFGNRFPTRPCPNKTSSPGR--T-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNVSDFLVKTYPALIRSRATTSRHEVRGAGVRISR--SLARYG
GISIGGKLPVVPVTREALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQVPLLLTQ-----------------STA--------
----------------------------

-------------------------------------MGFLRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNMNNPCF
QNPTPGESPGTVSNYNNSI-----------LARLYRDFQELFMDTPEVQRLGRVWTELRT
LSQLMDTLRTHPERFTGRGLPIRDILKDEETLTLFLKKNIGLSDSVAYLLVNSQ-VRMEQ
FAYGVPDLELKDIACSEALLQRFIIFSQRWGAQAVRGALCPLSQVTLQWIEDTLYADVDF
FKLFRVLPTLLDS-SSQGINLRFWGEILSDLSPRVQKFIHRPSVQDLLWVTRPLLQNSGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRRDPTYSYD-KRT--
-----------------TWRATKPLLMGKILFTPDSPAARR-LLKNANSTFEELDRVRKL
VKAWEEVGPQIWYFFEKSTQMAVIRDTLQHPTVKDFINRQLGEEGI-TTEAILNFFPNGP
RENQADDMTSFDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGIVR

PF12698 // ENSGT00760000118965_5_Domain_0 (678, 917)

SQTPAEPPIGVYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFATATIMQCFLFSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKTT----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEIEDPE--------------------------------------------------
------------------YPE---DSFFERELPGLVPGVCVKNLVKVFEPGSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIEISLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEARLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRCGCEGAC-SCTSKGFSA-
RCPARVDEITEEQVLD--GDVKELTDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSESGS-------------------
KFVGGTQQKREHTGLRHPCSAPVEKHRQHAQASHTCSPGQV-DPPKGQPS-PEPEDPGIP
FNTGARLILQHVQALLVKRFHHAVRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQFTFFSMDEPNNEHLEVLADVLLNRPGFGNRCLKE----------EWLP-E
YPCGN--ATSWKTPSVSPNITHLFQKQKWTAAHPSPACKCSTREKLIMLPECPEGAGGLP
PPQRIQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPDIPISGEALVGFLSDLGQMMNVSGGPVTRESSREMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETKDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
IDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWMTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSTDNLPALVTLLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNRMLLRFSATLRELLIVFPHFCLGRGLIDLALSQAVTDI
YAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--AEPAREPV-
-------FDEDDDVAEERQRVMSGGSKSDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVHPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALT
GCPPLLLLDEPTTGMDPQARRMLWNTIVNIIRQGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCMGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGASWQAKLEGKSGRLETQEPLPAGSSEHLAN----INNPTAV
ADNKHTRSPQ------------------

-------------------------MVEVRVKERRQGGFSCTC-TKTQVWKEFV-----L
LRILVELIWPLSLFLALVWLRKANPLYRQHECHFPNKAMPSAGTLPWLQGIFCNMNNPCF
RSPTRGEGPGVVSNYNNSI-----------LARVYRDAQELLLEAPEIHDLGRVWEELII
MTQFMETMRTNPERIAGRGIRILDILKDGETLTSFLLENVGLPDAVVFQLVNAQ-VRPEQ
FAYGVPNLTLKDIACSQMLLDRFIIFSSRRGLPSVHKAMCALSQEGLQRVEDALYANVDF
FKLFQLLPTVLDR-NSPGADLRSWGRVLSNVSQAVQKLARRQSVQDLLMVLQPFVQDGIP
ESLGHLVSSLSDLFCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTK-KSVYLYD-NTTTP
FCNELIQNLESNPLTKIAWSAVKPLLMGKILFAPNSPPVRQ-IIKNANSTFEELERLRLL
TKAWEEVGPQLWYFFQNSLQMNMIRDSLKHSTVRDFLNSQLGAEGL-TAEYIINFLHNGP
PGSREKGAVDFDWRNIFIAADQVLRLVSQYLECLTLDKFEGYHDETQLTHQA-LHLLEEN
KFWAGVVFPDI-DPTRKSLPPHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDFRYI
WGGFAYLQDMIEHGIIKTQTN

PF12698 // ENSGT00760000118965_5_Domain_0 (682, 917)

TDVALGIYLQQMPYPCFVDDV-FMITLNRSFPIFMVLAW
IYSVSMTVKSIVLEKEMRLKEAMKNRGVTNGVIWCTWFLDSFFMMAVSTFLLTALIMHGQ
VLHYSSPLLFFLFLLTFSTATIMQCFLFSTFFSKANLAAACSGVLYFTLYLPHIVCFVWQ
DRITVNLKIL----ASLLSQVAFGFGTEYLSRYEEQGLGLQWGNIRTSPLEGDEYSFLFS
IKMMLFDAFLYGILSW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DHVFPGEYGLPQPWYFPLQESYWLES---------------
---EGCVDQKAMDGERNESRT---KKSEEPEKQEE-------------------------
---------------------KNVNTFCEPEPTGLIPGVCIQNLVKIFANRPKPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRMN
ITFYEGQITAFLGHNGAGKTTTMSILTGLFPPTSGTVLIGGLDIQTHMDSIRQRLGMCPQ
YNILFNHLTVAEHILFYSQLKGRSRDEAEQELEMMLEDMGLTHKRNEEAQNLS--GGMQR
KLSVAIAFVGEAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIILSTHHMDEADILGD
RIAIISQGKLFCSGSPVFLKNCFGSGFYLTLVRKVKNTRTGRSVSLCSC-GSQCSCSC-S
SCALMDKEGTQEQELG--GDLNELAEVINHHIPEAKLIENIGQELVYLLPNKHFKQRSYA
SLFRE-LEETLDDLGLSSFGVSDTPLEEVFLKVTAEADPEVQKA----------------
---GDTQGNNST---PGKISTENRTAEQTPVETNDT-----SRMPAGIAGDQNE-GKGSL
QYKGFQLVHQQFKALFIKRFHHASRSYKDFLTQIVLPASFVLLSLVLTVIIPPFGEYPAL
TLDPWIYGQQFTFFSNERPGSEQMVSLTNAFLNKPGFGNRCLKN----------QPLL-N
FPCNNS-PTAWYIPAVHPKLSSLLLSQKWSSENPSPSCKCSTHKKLTMLPECPPGAGGLP
PPQRVQHSTEILQDLTHRNISDFLVKTYPMLIKGSLKSK----------YWV--NEQRYG
GISIGGKLPVLHVSGDEVVNFLSNLGRMMNVTGGQTSLAAAKEFS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2077)

NFLKYMETEDNIKVW
FNNKGWHAMVSFLNVANNAILRASLRTGQAPEEYGITA-VNHPLNLTKEQLSEVTVLTTS
VDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPAMYWLTNFTWDIVNYAV
SAGLVVVIFIGFKKKAYTSRTNLPVFVALLLLYGWAAIPMMYPASSFFSVPSTAYVALSC
INLFVGINSSAITFILELFENNPTLLKFNKTLKNVLIVFPHFCLGRGLIDLAINQAVSEV
YARFGEEHVSNPFQWDFIGKNLVAMAVQGVAFFTLN

ENSGT00760000118965_5_Linker_2_3 (2077, 2150)

LLMQHQLFPSRWF--AETAKSPI-
-------IDEDEDVAEERKRILNGGNKTNILELQELTKIYAGRHKPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGIRPGEC
FGLLGV-NGAGKTTTFKMLTGDTEVTSGDAVVAGNSILTHISNVHQNMGYCPQFDALDDL
LTGREHLYLYARLRGVPAEEIKRVAEWGIQKLGLPMYADQLAGTYSGGNKRKLSTAIALI
GCPPLILLDEPTTGMDPQSRRLLWDSIVSVLRDGRAV-----VLTSHSM-----------
EECEALCTRLAIMVKGTFKCLGTIQQLKYKFGDGYIVTLKIKAPKTGMPPDPSRAEQFIR
INFPGSLQREKHYNMLQYQICSSSLAKIFRLIISNKENLYIEEYSVSQTTLDQ--VFVNF
AKQQVE-DEEIPLHPRAAGSNRETKVSPASQQQADA------------------------
----------------------------

--DTS-AESGALCGVHV--HYHSSLGSERPGLCTVSSMGFARQ-IQLLLWKNWTLRKRQK
IRFAVELVWPLSLFLVLIWLRNANPLYSQHEXXXXXXXXXXXXXXXXXXXXXXXXX----
-------XXXXXXXXXXXXXXXXXXXXXXXLARVYRDFQELLRDAPESQHLGRVWTELRT
LSQFMNTLRTHPERMAGRGIRVRDILKDEETLVLFLKRNIGLSDSVAHLLVNSQ-VRPEQ
FAHGVPDLALKDIACSEALLTRFLIFSQWHGAQTVRGALCPLSQGTLQWMEDTLYANVDF
FKLFRVLPTLLDS-SSEGIDLRSWGRILSDISPRIQEFVRQPSVQDLLWATRPLIQHNGS
QSFTQLTAILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSARKDPVYTYD-KRTTS
FCNVLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERLRKL
IKAWEEVGPQIWYFFDKSPQMNMIRDTLQNPAVRDFWLXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSIMSMSIFLLTLFIMHGR
ILHYSDPFIL-LFLLAFSTATIMQCFLLSTFFSKTSLAAACSGVIYFTLYLPHILCFAWQ
DRLTAELKMAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX-XXXXXXDYGTPLPWYFLLQESYWLGGEGCSTREEKALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPGGTKDSFFEREHPGLVPGVCVKNLVKVFEPFGRPAVDCLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETSLNAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRPGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCLGTGFYLTLVRRMKTMQSQGGCCEATC-RCASRGVSR-
RCSTRNNEMAFEQTLD--GDVDELVDVVCHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDADSGL-------------------
-FTGDPQHKRVPGSLLRTGLGSSEKAAAAGEAAQA------SAPSEDPPSP-DPEGVGLP
LNRGTRLIAQHVQALLIKRFHHALRSHKDFLAQIVLPVTFVCLALMLSIIVPPFGEYPTL
TLHPWMYGQQYTFFSMDEPGSQPLTNLMDILLNKPGFGTRCLKE----------EGTL-D
YPCGN--STPWKTPAVSPNITHILQKQTWTPDNPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSGEVLQDLSNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAVPVTGTALVAFLSDLGHLMNVSGGPVTKEAAKDMADFLKYLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLQQDRNPEEYGITA-ISQPLNLTKEQLSEITVLTTS
VDALVAICVIFAMSFVPASFVLYLIQERVSKAKHLQFINGVSPTTYWLTNFLWDIMNYAV
SAGLVVCIFIGFQKKAYTSPDNLPALIALLMLYGXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX-
-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXC
FGLLGL-NGAGKTSIFKMLTGDKPVTSGDAFXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVRGTFQCLGTIQHLKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVFVNF
AKQQTE-IHDLPLHPRAAGANQPAKV----------------------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGVLPWLQGIFCNMNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVFQDFQELLIDAPENQHLGQIWRDLQT
LSRLMDTLRTHPERIAGRGIQIRNVLKDEETLTLFLRKNIGLSNSVAHLLVNSQ-VRVQQ
FAHGVPDLVLKDIACSEVLLERFIIFSQRRGAHTVRDALCSLSQGTLQWMEDTLYANVDF
FKLFQVLPTLLDS-GSQGINLRFWGRILSDMTPRIQEFIHQPSVQDLLWVTRSLLQNRGP
ETFTELKGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGMDSTRKDPSYSYD-KRTTP
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERLRKL
IKAWEEVGPQIRYFFDNSTQMTMIRDTLEHPTVKDFLNRQLGEDGI-IVEAMKSFLYKGP
QENQADDITNFDWRDIFNITDLSLRMAGQYLECLVLDKFESYDDEIQLTQQA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAYLQDMVEQGITRSQARKEA

PF12698 // ENSGT00760000118965_5_Domain_0 (685, 917)

PIGVYLQQMPYPCFVDDS------NRCFPIFVVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSVMSMSIFLLTLFIMHGR
ILHYSDPFIIFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DQMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPMEGDEFSFLLS
MQMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1078)

YL-DQVFPGNYGTPLPWYFLLQESYWLSGEGCSTREERTLEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGMNDSFFEHELPGSVPGVCVKNLVKIFEPSGRPAVD

PF00005 // ENSGT00760000118965_5_Domain_1 (1078, 1222)

YLN
ITFYENQITAFLGHNGAGKTTTLSILTGLMPPTSGTVLIGGKDIETNLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMETMLEDTGLHHKRNKEAQNLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRAGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPFFLKNCFGTGFYLTLVRKMKTIQSQGGRCEGTC-SCASKGFSV-
RCPARVDEITPEQVLD--GDVNELMDVVCHHIPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLPDLGLSSFGISDTPLEEIFLKATEESDSGL-------------------
LFAGSTQQKREHVNLRHPCLGPSKKDRQPTQGSNICSL-EQAAHPEGQAPPEPE-EPNIP
LNTGMRLILQQVQALLVKRFHHTVRSHKDFLAQIVLPATFVFLAQMLSIIVPPFGEFPAL
TLHPWIYGHQYTFFSMDEPGSERLAVLADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNVTHLFQKQKWTPSNPSPSCTCSTREKLTMLPECPEGAGGLA
PPQRTQGSTEILQDLSRRNISDYLVKTYPALIRNSLKSK----------FWV--NEQRYG
GISIGGKLLVLPITGKALVGFLSDLGQIMNVSGGPITREASREMS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNVKVW
FNNKGWHALVSFLNVAHNAILRASLPQDRHPEEHGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLTQERVTKAKHLQFISGVSSTTYWLTNFFWDIMNYAV
SAGLVVGIFIRFQKKAYTSTENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLARFNAMLRKLLIIFPHFCLGRGLIDLAVSQAVTDV
YAWFGKEHSSNPFQWDMIGKNLVAMAVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2151)

LVQHHFFLTRWV--AEPAKEPI-
-------VDEDDDVAEERQRITSGGNKTDILRLNELTKVYSGSSSPAADR

PF00005 // ENSGT00760000118965_5_Domain_3 (2151, 2292)

LCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGETTVTSGDATVAGKSILTNIFDVHQRMGYCPQFDAIDDL
LTGREHLYLYARLRGIPAEEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSLIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNLVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGARQQAKVLLLLSLR--ALLE-----------EPLSIGSSEP
--LASI-SDPAAAGNKHMRSCS------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFIVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGVLPWLQGIFCNVKNPCF
QSTTPGESPGIVSNYNNSV-----------LARVYRDFQELLMNAPESPHFGHVWAELRT
LFQFMDTLRTRPGRIAGRGIRIRDILRDEETLTLSLIKNIGLPDSVVYLLVNSQ-VRPEQ
FAHGIPDLALKDIACSEALLERFIIFSQRRGAQTVYHALCPLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSVQDLLWVSRPLMQSGGP
GTFTQLMGVLSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTS
FCNALIHSLESNPLTKIAWRTAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERLRKV
VKAWEEVGPQIWHFFDNSTQMNMIRDTLGNPTVKAFLNRQFGEEGI-TAEAILNFLYNGP
RESQAEDTANFDWRDIFNVTDRTLRLANQYLECMVLDKFESYSDEIQLTHRA-LSLLEEN
RFWAGVVFPDM-HPWTNSLPPHVKYKIRMDIDAVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQV

PF12698 // ENSGT00760000118965_5_Domain_0 (681, 917)

RARAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKENLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPCILFLFLLAFSTATIMLCFLLSTFFSKANLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKRT----VSLLSPVAFGFGTEYLVRFEEQGLGLQWNNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1079)

YL-DQVLPGDYGTPLPWFFPLQESYWMGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HPGGLNDTFFERELPGLVPGVCVKNLVKLFEPHGRPAVDC

PF00005 // ENSGT00760000118965_5_Domain_1 (1079, 1222)

LN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVIRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGRSWEEAQLEMESMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFMGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1788)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKSCFGTGFYLTLVRKMKNIQSQKRSCEGPC-DCASKGFSA-
SCPACVSDLTPEQVLD--GDVNELMDVVFHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLTDLGLSSFGISDTPLEEIFLRVTEDSYSGP-------------------
LFDGGAQQKGENVSLRHPCLGPREKAGQTPQDTNVCAPGAPAAPPEGQPAPEPE-VPGLR
LNMGVRLVFQHVQALLVKRFHHAIRSHRDFLAQIVLPATFVFLALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDDLGSERLAVLADVLLNKPGFGNRCLKD----------EWLP-A
YPCGN--STPWKTPSVSPNVTHLFQKQKWTPDNPSPSCMCSTREKLTMLPECPEGAGGLP
PPQRMQRSSEILQDLTGRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPRIPITGEALIDFLSDLGQIMNVNRGPVTREAAKEMSEF

PF12698 // ENSGT00760000118965_5_Domain_2 (1788, 2078)

LKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPQDKNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVSICVIFAMSFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAIIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNQMLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEAHSSNPFQWDLIGKNLAAMAVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQHHFFLSQWT--TEPTKEPI-
-------VDEDDDVAEERQRIANGGNKTDILRLNELTKVYPGTSSRAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIKRVANWSIKSLGLSVYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYVVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGANQQAKD----------------------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELLWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGVLPWLQGIFCNMNNPCF
QSPTPGESPGIVSNYNNSI-----------LAKVFRDFKEFLIDAPESQQLGQIWTDLRT
LFHLVDTLRTRPERTAGRGIQIRDILKDEETLTLFLMRNIGLSNSVAHLLVSSQ-VRVEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGGNIVRDALCSLSQGTLQWMEDTLYANVDF
FKLFRVLPTLLDS-SSKGIDLRSWGRTLSDMSPRIQEFIHQPSVQDLLWVTRPLLQDRGP
ETFTQLLGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTP
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDAPAARR-ILKNANSTFEELGRFRKL
VKAWKEVGPQIWYFFANSTQMTMIRDTLGHPTVKDLLNRELGEDGI-TVEAMLNFLYKGP
RESRADDKTNFDWRDIFNITDRSLRLADQYLECLVLDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAY

PF12698 // ENSGT00760000118965_5_Domain_0 (667, 917)

LQDMVEQGITRSQARVEPPIGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNHGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPFIVFLFLLTFATATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DQMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGSSPMEGDDFSFLLS
MQMMLLDAALYGLFAW

ENSGT00760000118965_5_Linker_0_1 (917, 1079)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALERTE
PITEEMEDPD--------------------------------------------------
------------------HPGGINDSFFERELPGLVPGVCVKNLVKIFESSGRPAVDC

PF00005 // ENSGT00760000118965_5_Domain_1 (1079, 1222)

LN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQELS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1798)

SGVDPYSRRSIWDLLLKYRAGRTIIMSTHHMDEADLLGD
RIAIISKGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQGGSCEGTC-SCASKGFSV-
RCPARVDEITAEQVLD--GDVNELMDVVRHHVPEAKLVECIGQEVIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGL-------------------
LFAGDTQQKREHVNLRHPCLGPSKKARQPDQGPNTCSL-EQDAHLEGQAPPEPE-QPSIP
LNTGTRLVLQHVQALLVKRFHHSVRSHKDFLAQIVLPATFVLLALMLSIIVPPFGEFPAL
TLHPWIYGQQYTFFSMDEPGSERLAVLADVLLNKPGFGNRCLKK----------VWLL-E
YPCGN--STPWKTPSVSPNVTHLFQKQKWTPSNPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQASTEILQDLTNRNISDYLVKTYPALIRGSF---------------L--LPHRYG
GISIGGKLLVLPVTAEAIVGFLSDLGQIMNVSGVCKQN------EDLSRIFELLNYN

PF12698 // ENSGT00760000118965_5_Domain_2 (1798, 2078)

KVW
FNNKGWHALVSFLNVAHNAILRASLHEDRHPEEHGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSSTTYWLTNFFWDITNYAV
SAGLVVGIFIGFQKKAYTSAQNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNQTLLRFNALLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWDMIGKNLVAMAAEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAREPI-
-------VDEDDDVAEERKRITSGGNKTDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTDISDVHQRMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAAEIERVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLMLLDEPTTGMDPQARRMLWNTIVSLIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNLVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGARQQSKELWA------ASAQ-----------EPLSIESSEP
RTS--T-SDPASAGNEHMRSSV------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNVNPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLVDAPESQHLGHIWTELRT
LSHLMDTLRTHPERVAGRGIRIRDVLKDEETLTLFLIKNIGLSDSVVHLLVNSQ-VRPEQ
FAHGVPDLVLKDIACSEVLLERFLIFSQRRGAQTVRDAICSLSQGTLQWMEDSLYANVDF
FKLFRVLPTLLES-SSQGINLRSWGKILSDVSPRIQEFIHRPSVQDLLWVTRPLLQTDGP
ETFTQLTGILSDLFCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTT
FCNALIQSLESNPLTKIVWRAAKPLLMGKILFTPDSPAARR-VLKNANSTFEELERLRKL
VKAWEEVGPQIWYFFDKSTQMTMIRDTLGNPTVRDFLNKQLAEEGI-AAEAVLHFLYNGP
RESRADNMADIDWRDVFDIADRTLRLANQYLECLILDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQAQAQVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKMA----VSLLSPVAFGFGTEYLARFEEQGLGLQWNNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGINDSFFERELPGLVPGVCVKNLVKIFEPHGRPAVDRLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHVLFYAQLKGRSWAEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGKLYCSGTPLFLKKCFGTGFYLTLVRRMKHIQSQGRVCEGTC-SCESKGFSI-
RCPAHEDEITPEQVLD--GDVNELMDMVRHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGH-------------------
LFAGGAQ-QRENVSLRHPCLGPSEKVRQTPQGSNGCSA-EPAPGAAGWPS----PQPGGR
LNSGARLRLQHVQALLVKRFHHAVRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPTL
TLHPWMYGQQYTFFSMDQPGSEQLAALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSLNVTHLLQEQKWTADNPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQDLTNRNISDFLVKTYPALIQSGLKSK----------FWV--NEQRYG
GISIGGKLPVLPITGEALVGFLSDLGQMMNVSGGPVTREASKEMSAFLKHLETEDNIKVW
FNNKGWHALVSFLNVGHNAILRASLHKDRNPEEYGITV-MSQPLNLTKEQLSEITVLTTS
VDAMVAICVIFAMSFVPASFVLYLIQERVSKAKHLQFISGVSPITYWLTNFLWDIMNYTV
SAALVVGIFIGFQKKAYTSPNNLPALVALLMLYGWAVTPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLSFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEQHSSNPFQWDLIGKNLVAMAAEGVVYFLLTLLIQYHFFLTQWI--GEPSKEPI-
-------VDEDDDVAEERQRIISGGNKTDILRLNELTKIYSGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEKIEKVAKWCIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRASSTALTLCPAHS-----------M
EECEALCTRLAIMVKGSFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFRLLLSHKESLLIEEYSVTQTTLDQAMVFVNF
AKQQTE-THDVPLHPRAAGASQQAKEVDKG-----------------------NSAPQG-
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELHI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLTLKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILMNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTNSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCLLLSTFFSKASVAAACSGIIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLMQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVNDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPGL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRFPTRPCPNKTGSPGRTQQ-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNVSDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLTDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMITGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNVIMSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQVPLLLTQ-----------------STA--------
----------------------------

EKDK-ADAGGA-LGIYVHCCPNL--SSEFMGLV-VAIMGFARQ-IQLLLWKNWTLRKRQK
IRFVVELMWPLSLFLVLIWLRNVNPLYSKHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHVWTELRT
LSQLMDTLRTHPKRIAGKGIRILDVLKDEETLTLFLMKNIGLSDSVVHLLVNSQ-VRPEQ
FAHGVPDLVLKDIACSEALLERFIIFSQRRGAQTVRDAMCSLSQGTLQWVEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRSWGKILSDLSPRIQEFIHRPSVQDLLWVTRPLMQTGGP
DTFTQLAGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSMRKDPVYSYD-KRTTT
FCNALIQSLEYNPLTKIAWRAAKPLLMGKILFTPDSPAARS-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDKSTQMTTIRDTLANPIVKGFLNKQFGEEGI-TAEAALNFLYKGP
RESQADDMANFDWRDIFNFTDRALRLANRFLECLILDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITKSQVGAEVPVGIYLQQMPYPCFVDDS-FMIIMNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNTVIWCTWFLDSFSIMSMSIFLLTIFIMXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXSLLSPVAFGFGTEYLARFEEQGLGLQWSNIGNSPMEGDEFSFLMS
MKMMLLDAALYGFLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEXXXXXXXXXXXXXX
XXXXXXXXXX--------------------------------------------------
------------------XXXXXXXSFFERELPGSVPGVCVKNLVKVFEPYGRPAVDRLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGLCPQ
HNILFHHLTVAEHILFYAQLKGKSWDEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCAGTPLFLKNCFGTGFYLTLVRKMKNIQSQKTGCKGTC-SCASKDSSI-
RCPAHVDEITPEQVLD--GDVNELMDVVHHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
NLFRE-LEETLAELGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFTGSTQQKRETISLRNPYLGSSKGY--------------SADPAQGQPSPEPK-QQGGR
LNTGAQLIFQHVQALLVKRFHHALRSHKDFLAQIVLPATFVFLALMLSIVVPPFGEYPAL
TLHPWMYGQQYTFFSMDQPGSERLTALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNVTHVFQKQKWTPEHPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRVQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLPITGEALVGFLSDLGQIMNVSGGPITREASKEMSAFLQHLETEDNVKVW
FNNKGWHAMVSFLNVAHNAILRASLPQDRNPEEYGITV-ISQPLNLTKEQLSEITVXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNYAV
SAALVVGIFIGFQKKAYTSPNNLPALVALLMLYGXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNAEPTKEPI-
-------IDEDDDVAEERQRIISGGSKTDILSLNELTKIYSGTSSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIMSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVFVNF
AKQQTE-IHDLPLHPRAAGASRQAKI----------------------------------
----------------------------

-------------------------------------MRFPRQ-IRLLLWKNWTLRRRQK
IRFVVELVCPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLLYAPESQHLSHVWTEIRT
LSQFMDTLRNHPERIAGRGIRIRDILKDEETLTLFLTRHIGLSDSVVNLLVNSQ-VRPEQ
FAYGVPDLVLKDIACSEALLERFIIFDQRWGAQTAHDALCSLSQGTLQWIEDTLYANVDF
FKLFHVXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXFIHRPSVQDLLLVTRPLMQNGGP
QTSTQLLSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVYSYD-KTTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPNSPATRR-IVKNXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXDTLENPTVKGFLDRQLGEEGI-TTAAILSFLSNGP
RESRADNMADFYWRDIFNITDRTLRLANQYLECLILDKFESYDDEIQLTQRA-LSLLEEN
KFWAGVVFPDM-YSWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPIEDFRYI
WGGFAYLQDMVEQGITRSQAQVGSPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMLMSILLLTLFITHGR
ILHYSNPFILFLFLTVFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKQA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWTNIGSSPMEGDDFSFLMS
MKMMLFDAALYGLLAWYL-DQVFPGDYGTPLPWFFFLQESYWLGGEVCSR-EERALEKTE
PVTEEMEDPE--------------------------------------------------
------------------RPGGMHESFFERELPGLVPGVCVKNLVKSFEPYGRPAVDRLN
ITFYENQITAFLGHNGAGKTTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX-X
XXXXCVDEITPEQVLD--GDVNELTDVVRHHVPEAKLVECIGQELIFLLLNKNFKQRSYA
SLFRE-LEDTLPDLGLSS--ISDTSLAEIFLKVTEDSDSGPLLA----------------
---GGTQQKKENLSLRQPCLSPSEEAKQTSQDSNVC-SAAAAAPPEGQPPTGPE-DPRTQ
LNTGTQLLLQHVQALLVKRFHHTLRSRKDFLAQIGLPASVEFLALMLS-IIVLFGEYPAL
TLHPWMYGQQYTFYSMDDSNSEHLELLADVLLNKPGFGNRCLKE----------EWLP-E
YPCGNS--TPWKTPAVSPNITHLFQKQEWLPEHPSPACRCSTREKLTMLPECPEGAGGLP
PPQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKSK----------FWV--NEQRYG
GISIGGKLPVPPFTADTLVGFLSALGQMMNVSGGPITREASKEMSDFLKYLETEDNLKVW
FNK---HAMVSFLNA--HAILRANLHXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXLTTS
VDAVVAICVIFAMSFVPASFVLYLIHERVNKAKHLQFVSGVGPITYWLTSFLWDIANYSV
SAGLVVGIFMGFQKKAYTSPNNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITXXXXXXXXXXMLIRLNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFXXXXXXXXXXXXXXXXXXXXXXXXXXXXFLLTLLIQHRCTLSRWN--AEPPKEPI-
-------VEEDDDVAQERQRIISGGSSNDILRLNELTKIYSGTSSPAVDRLCVGVRPGEX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00005 // ENSGT00760000118965_5_Domain_3 (2197, 2356)

ILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANQSIQSLGLSQYADRLAGTYSGGNKRKLSTAIALL
GGPPLVLLDEPTTGMDPQARRMLWNTIVGIIRQGRAV-----VLTSHRQEIPGT--GGQD
RECEALCTRLAIMVKGTFRCLGTIQHLKYKFGDGYVVTMKIKAPKGELLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQAMVFVNF
AKQQTE-SHDIPLHPRAAGANRAKVR----------------------------------
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGS-------------------
MFVGATQQKREQAGLRHPCSAPTEKLRQPAQAPHTCSPGQV-DPPKGQPS-PEPEDPGVP
FNTGARLILQHVQALLVKRFHHAIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPNNEHLEVLADVLLNRPGFGNRCLKE----------EWLP-E
YPCIN--ATSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPISGEALVGFLSDLGQMMNVSGGPVTREASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETTDNIKVW
FNNKGWHAMVSFLNVAHNAILRASLPRDRDPEEYGITV-ISQPLNLTKEQLSDITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSC
ANLFIGINSSAITFVLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--AEPAREPV-
-------FDEDDDVAEERQRVMSGGNKTDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALT
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-AYDLPLHPRAAGASWQAKLEGKSGRLQTQEPLPTGS-EQLAN----GSNPTAA
E-DKHTRSPQ------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSHHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELHI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAKTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIHRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELEHVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRA-LSLLEEN
MFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPCGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCSSKGFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTQVNPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-SHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQAILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVDNLTPEQVLD--GDVNELMDVVLHHVPEATLVECIGQELIFLLPSKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENINPQRPCLGPREKAGQTPQDSNVFSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLQELTKIYPGTSSAAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASQQAQVPLLLTQ-----------------STA--------
----------------------------

------------------------------------MN-FLRQ-IRLLLWKNWILRKRQK
LRLLVELVWPLSLFLALVWLRKANPLYRQHECHFPNKAMPSAGTLPWLHGIFCNMNNPCF
RSPTPGESPGVVSNYNNSI-----------LARVYKDAQELLLEAPEIRDLGRVWEELII
MTQFMETMRTNPERIAGRGIRILDILKDGETLTSFLLEDARLPDVVVFQLINAQ-VRPEQ
FAYGVPNLTLKDIACSQMLLDRFIIFSSRRGLPSVHKAMCALSQESLQRVEDALYANVDF
FKLFQLLPTVLDR-NSPGVDLRSWGRVLSNVSQAAQKLAKKSSVQDLFKALQPFVQNGRT
ESLGHWVSSMSDLFCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTK-KSSYLYD-NTTTP
FCNALIQNLESNPLTKIAWSAVKPLLMGKILFAPDSPSVRQ-ILKNANSTFEELERFRLL
TKAWEEVGPQLWYFFQNSLQMNMIRDSLKHPTVRDFLNRQMGAEGL-TAEHIINFLHNGS
PGTREKGMVDFDWRNIFSVVDQALRLLSQYLECLMLDKFEGYHDETQLTHQA-LHLLEEN
KFWAGVVFPDI-EPIASSLPPHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDLRYI
WGGFAYLQDMIEHGIIKTQTNTEVPIGIYLQQMPYPCFVDDV-FMITLNRSFPIFMVLAW
IYSVSMTVKSIVLEKEMRLKEAMKNRGITNGVIWCTWFLDSFVMMAVSTFLLTALIMCGQ
VLHYSSPLLFFLFLLTFTTATITQCFLFSTFFSKANLAAACSGVLYFTLYLPHIVCFVWQ
DRMTVNLKIL----ASLLSQVAFGFGTEYLSRYEEQGLGLQWGNIRTSPLEGDEYSFLFS
IKMMLFDAFLYGILSWYL-DNVFPGDYGLPQPWYFPLQESYWFGSRNPKAEKPATIDENS
PQSECCVDQKAMEGEKNESRT---KKSEEPEKPEEKSDNQGEKDGKNKQCKHKREKEPGE
QGMPK--TDVQDKDEMNSKEREQLNTFCEPEPTGLIPGVCVQNLVKIFANRPKPAVDGMN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

GQITAFLGHNGAGKTTTMSILTGLFPPTSGTVLIGGLDIQTHMDSIRQQLGMCPQ
YNILFNHLTVAEHILFYSQLKGRSRDEAEQELEMMLEDMGLTHKRNEEAQKLS--GGMQR
KLSVAIAFVGEAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIILSTHHMDEADILGD
RIAIISQGKLFCSGSPVFLKNCFGSGFYLTLVRKMKNTRIARNASFCSC-GSQCSCSC-S
SCAHRDKEGTQVQELD--GDLNELAEVIHHHVPEAKLIESIGQEIVYLLPSKHFKQRSYA
SLFRE-LEETLDDLGLSSFGVSDTPLEEVFLKVTAEASPEMQKVHNCVNKDVVSIPQMSV
VFIGDNQENGST---CGKISTENKTAEKNPLETNDT-----SQMPVGIAGDQNE-GKGSR
QYKGFQLVHQQIKALFIKRFHHASRSHKDFLAQIVLPASFVLLSLMLTVIIPPFGEYPAL
TLHPWIYGQQFTFFSNEGPGSEQMVSLTDAFLNKPGFGNRCLKN----------QPLP-N
YSCNNM-ATAWNTPVVHPNLSSLLLSQKWSSENPSPSCKCSTRKKLTMLPECPPGAGGLP
PPQRVQHSTEILQDLTHRNISDFLVKTYPVLIKGSLKSK----------YWV--NEQRYG
GISIGGKLPVLHVSGDEVVDFFSDLCRMMNVTGGQTSLAAAKEFSNFLKYMETEDNIKVW
FNNKGWHAMVSFLNVANNAILRANLRTGQAPEEYGITTVVNHPLNLTKEQLSEVTVLTTS
VDALVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPAIYWLTNFMWDIVNYAV
SAGLVVVIFAGFKKKAYTSPTNLPVLVALLLLYGWAVIPMMYPASSFFSVPSTAYVALSC
INLFVGINSSAITFILELFENNPTLLKFNKTLKNVLIVFPHFCLGRGLIDLAINQAVSEV
YARFGEEHVSNPFQWDFVGKNLVAMAVQGVAFFILNLLMQHRLFSSRWF--AETTKSPV-
-------TDEDEDVAEERKRIMNGRKKTDILELQELTKIYAGRHKPAVDRLCVGIRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTDVTSGDAVVAGNSILTDISSVHQNMGYCPQFDALDDL
LTGREHLYLYARLRGVPAEEIKRVAEWGIQKLGLPMYADQLAGTYSGGNKRKLSTAIALI
GCPPLILLDEPTTGMDPQSRRLLWDSIVSVLRDGRAV-----VLTSHSM-----------
EECEALCTRLAIMVNGTFKCLGTIQQLKYKFGDGYIVTLKIKAPKAGLPPDPSRAEQFIR
INFPGSLQREKHYNMLQYQICSSSLAKIFRLIISNKENLHIEEYSVSQTTLDQ--VFVNF
AKQQME-DEEIPLHPRAAGASREAKVSPA-------------------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
RSTTPGESPGIVSNYNNSI-----------LARVYRDFQELLMDAPESQHLGQVWTELRT
LSQFMDTLRTHPQRIAGRGIRIRDILKDEETLTLFLIKNIGLPDSVVYLLVNSQ-VRPEQ
FAHGVPDLALKDIACSKALLERFIIFSQRHGAQTVYQAMCPLSQGTLQWVEDALYANVDF
FKLFRVLPTLLDS-SSQGINLRSWGRILSDMLPRIQEFIHRSSVQDLLWATRPFTQNGGP
ETFIQLTGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDATRKDPIYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERVRKL
LKAWEEVGPQIWYFFDKSTQMTMIRDTLANPAIKAFLSRELGEEGI-TAEAILNFLYTGS
PESRDDDMANFDWRDIFNITDRTLRLVNQYLECLILDKFESYDDEIQLTHRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAY

PF12698 // ENSGT00760000118965_5_Domain_0 (667, 917)

LQDMVEQGITRSQTGAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
ERLTVDLKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPVEGDEFSFLLS
MEMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGMRDSFFERELPGLVPGVCVKNLVKMFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNMQSQRRGCEATC-TCASKGLPI-
SCPACVNGITPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGT-------------------
LFAGGTQQKWENASLRQPHLGPGEKAGQLPQGSNNQGP-AP----EDQPSP-PA-DPSTQ
LNVGARLVLQHVQALLVKRFHHTVRSRKDFLAQIVLPATFVFLALTLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSERLAVLADVLLNKPGFGNRCLKD----------EWLL-E
YPCGN--STPWKTPSVSPNVTHLLQKQQWTPDDPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVIPVTGEALVGFLSNLGRMMNVSGGPITREASKEVS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLEAQDNIKVW
FNNKGWHAMVSFLNVAHNAILRASLHKDRDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSSTTYWLTNFFWDIMNYAV
SAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNQTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWDLIGKNLAAMALEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQHHFFLTQWI--AEPSKEPI-
-------VDEDDDVAEERQRIISGGNKTDILRLNELTKIYSGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANWSIKSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVRGTFRCMGTIQHLKYKFGDGYIVTMKIRSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IYDVPLHPRAAGASQQPKA----------------------------------
----------------------------

EKDTATGAGGTLSSVYVLCRLGGLSSDQ-SGLCVGISMGFVRQ-IQLLLWKNWTLRKRQK
I-------------------------------HFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMKAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIHRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKITWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMDNFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDNFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLS
MQMMLLDAAVYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAVDRLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSREEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCSSKGFST-
TCPAHFDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPSPEPE-CPGPQ
LNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQQSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIPDFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMLVEGVVYFLLTLLVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRIITGGSKTDILRLHELTKIYPGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIRERRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------VDVVCHHVPEAKLVESIGQEVIFLLPNKNFKRVPPC
LVLRLGFFLTLRYLFYSSFYHIRS---RTYA-YVSEFLTQP-------------------
PQIGGTQQKRERVNLRHPCLGPSKKARESTQGSNTCCPQQ-ATHTEGQLPSEP-EQPSIP
LNTGVRLALQHVQALLVKRFHHTVRSHKDFLAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGQQYTFFSMDEPSSERLAVLAESLLNKPGFGNRCLKE----------AWLR-E
DPCSN--ATPWKTPSVSLNVTHLFQQQKWTPSNPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQGSTEILQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRWY
GRRITGWG------GREWVGES----QGEGQRHGPITREVSREMS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLRHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPADRHPEEHGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSSTTYWLTNFFWDMMNYAV
SAGLVVGIFIGFQKKAYTSTQNLPALIALLMLYGWSVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNALLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEYTSNPFQWDMIGKNLVAMAVEGVLYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2199)

LIQHHFFLTRWY-----------
----------------------TGGNKTDILKLSELTKVYSGSSTPAVDRLCVGVRPGEV
GTLPSSLKGLQKTSFYEA-----------LLSYKASIL

PF00005 // ENSGT00760000118965_5_Domain_3 (2199, 2292)

TNISDVHQRMGYCPQFDAIDDL
LTGREHLYLYARLRGIPTEEIERVANWGIQSLGLSPYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSLIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLEGGGTP---FAA-------------SWGFDQALLEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ-------
------------------------------------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELLWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERITGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RENQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRA-LSLLEEN
MFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCSSKGFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKTGQTPQDSNVCSPGAPAAHLEGQPPPEPE-CPGPQ
LNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRCLRE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQGQVPLLLMQ-----------------STA--------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
MRFVVELVWPLSLFLVLIWLRNVNPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNLCF
QNPTLGESPGIVSNYNNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X
--X--XXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
FVHGVPNLMLKDIACSEALLKRFLIFSQRRGAQTVRDALCPLSQGTLQWMEDTLYANIDF
FKLFRVFPTLLDR-SSQGIDLRSWGRILSNMSPRIQEFIHQPSVQDLLWVTRPLVQTDSP
RTFTELMGILSNLFCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTKKDPIYSYN-TRTTT
FCNALIQSLESNPLTKIAWRAAKPLLIGKILFTPDAPAARR-VLKNANSTFEELERFRNL
IKAWEEVGPQIWYFFDRSTQMTMIRDTLENPTVKDFLNKQLDEEGI-TAEAALNFLYNGP
RGSRADDLANFDWKDVFNVTDHTLRLVNQYLECLVLD-FESYDDEIQLTQRA-LSLLSEN
RFWAGVVFPDM-YPWTSSLPAHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMIELGITRSQVQTKSPIGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMNIFLLTIFIMHGR
ILHYSNPFILFFFLLAFSTATTMQCFLLSTFFSRASLAAACSGVIYLTLYLPHILCFAWQ
DRMTADLKMV----VSLLSPVAFGFGTEYLVRFEEQGLGLQWNNIGNSPVEGDEFSFLMS
MKMMLLDSALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWMGGEGCSTREERALEKTE
PITEEMEDSE--------------------------------------------------
------------------HPEGIKDSFFERELPGLVPGVCVKNLVKIFEPYGRPAVDHLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDEVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAKLEMEAMLEDTGLHHKRNEEAQDLS--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRTIIMSTHHMDEADLLGD
RIAIISQGKLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRTCKXXXX-XXXXXXXX--
--XXXXXXXXXXXXXXXXXDVNELIDMVSHHVPEAQLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEEALADLGLSSFGISDTPLEEIFLKXXXXXXXXX-------------------
XXXXRTQQKRENLNFRHPGVDPTERVRQTSQGSNSCSVEP--TLPDGQS---PGESESTT
LNRGARLVLQHMQALLVKRFHHSVRSHKDFLAQIVLPAMFVCLALMLSIIVPPFGEYPAL
TLHPWMYGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XX-X-X
XXXXX--XXXXXXXXXXXXXXXX-XXXX-XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXLKSKFWV--NEQRYG
GISIGGKLPALPITGDALVAFLGDLGQLMNVSGGPVTREAAKEMSAFLKHLETEDNIKVW
V-NKGWHAMVSFXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFISGVSPITYWLTNFIWDMMNYAV
SAALVVGIFIGFQKKAYTSPNHLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNQTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHTSNPFQWDLIGKNLVAMAAEGVVYFLLTLLTQHHFFLTRWV--AEPAKEPI-
-------LDEDDDVAEERQRIANGGNKTDILRLNNLTKXXXXXXXXXXXXXXXXXXX

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

XXC
FGLLGV-NGAGKTTTFKMLTGDTSVTSGDATVAGKSILTSISDVHQSMGYCPQFDAIDDL
LTGKEHLYLYARLRGVPAGEIDQVANWSIKSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIMSIIREGRAV-----VLTSHRREILGGRLGWTG
AECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQAKVFVNF
AKQQTE-THDLPLHPRAAGANQQAKI----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTKKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARK-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQPILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFELEHPGWVPGVYVKNLVKIFEPYGRPAVDRLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTSGTVLVGGMDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVDDLTPEQVLDVLGDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPGPE-CPGPQ
LNTGAQLVLQHLQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPVTGEALVGFLSDLGRIMNVSGGPITREASKEIPDFLQHLETEENIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTLLVQRHFFLSQWI--ADPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTMQHLKSKFGDGYFVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLMEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQV----------------------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFAVELMWPLSLFLVLIWLRNVNPLYSKHECHFPNKAMPSAGILPWLQGIFCNVNNPCF
KSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMDAPESQHLGQVWTELRT
LSQLMDTLRTHPERIAGRGIRIRDILRDEETLTLFLMRNIGLSDSVVHLLVNSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFVIFSQRRGAQTVREAMCALSQGTLQWMEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRSWGRILSDMSPRIQEFIHRPSVQDLLWVTRPLTQTGGP
ETFTQLTGVLYDLLCGYPEGGGSQVFSFNWYEDNNYKAFLGIDAKRKDPIYSYD-KRTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDKSTQMTMIRDTLANPTVKGFLKRQFDE-EI-TAEAVLNFLYKGP
RENRADDMANFDWRDIFNTTDRALHLANQYLECLVLDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDPGPRADPVEDLRYI
WGGFAYLQDMIEQGVTRSQARAEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNTVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGVLYLTLYLPHILCFAWQ
DRMTADLKMA----MSLLSPVAFGFGTEYLARFEEQGLGLQWSNIGKSPMEEDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREARALERTE
PVTEEMEDPE--------------------------------------------------
------------------HPEGVTDSFFERELPGLVPGVCVKNLVKVFEPYGRPAVDRLS
INFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGLCPQ
HNILFPHLTVAEHILFYAQLKGKARDEAQLEAEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVVIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCAGTPLFLKNCFGTGFYLTLVRKMKSVQGQRTGCEGTC-GCASKGFSI-
RCPAHADERTPEQVLDVLGDMNELMEVVRHHVPEAKLVESIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGNTQQKRETVSLRHPCSGSSKEVTQTPQGSNSCSA-EPAPPTQGQPSREPA-EQGGR
RNTGARLVIQHVQALLVKR-HHSVRSRKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDQPGSERLAALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STAWKIPFVSPNVTHLFQKQKWTPDHPSPSCWCSTREKLTMLPECPEGAGGLP
PPQRMQRSTEILQDLTDRNISDFLVKTYPALIRTSLKSK----------FWV--NEQRYG
GISIGGKLPALPITGEALVGFLSDLGQMMNVSGGPVTREAAKEMSVFLRHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRAGLHPDRDPEEYGITV-LSQPLNLTKEQLSEITVLTTA
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYAV
SAALVVGIFVGFQKKAYTSPNNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNPTLLRFNALLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEKKSPNPFQWDLIGKNLVAMAAEGAVYFLLTLLIQHHFFLTRWI--AEPTKEPI-
-------VDEDDDVAEERQRIISGGNKTDILSLNELTKIYSGTSSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVATWSIQSLGLSLYGDRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHNMLQFQVPSSSLARIFRLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQHTE-THDLPLHPRAAGASGQAKQDRSSGQREGQEP-----------------LPRGR
PSRPASISKASAAETNTW-AYTDP---Q

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRLVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGVLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LAKVFRDFQELVLDAPESQHLGQVWTDLRT
LFQLMHTLRTSPERTAGRGIQIRDILKDEETLTLFLMKNIGLSNSVAHLLVNSQ-VRVEQ
FAHGVPDLALKDIACSQALLERFIIFKQRRGGSIVRDALCSLSQGTLQWMEDTLYANVDF
FKLFRVLPTVLDS-SSQGINLRSWGRTLSDLSPRIQEFIRRPSVQDLLWVSRPLLHNGGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSARKDPIYSYD-KRTTP
FCNALIQSLESNTLTKIAWRAAKPLLMGKILFTPDSRAVRR-ILKNANTTFEELERIRKL
VKAWKEVGPQIWYFFDNSIQMTMIRETLEHPTVKNFLNRELGEDGI-TVEAVLNFLYKGP
RESQAEDVTNFDWRDIFNITDRSLRLADQYLECLVLDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMIEQGITRSQAQVETPIGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFFIMSMSIFLLTLFIMHGR
ILHYSDPFIVFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DQMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPMEGDGFSFLLS
MQMMLLDAALYGSLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1079)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------YPEGMKDSFFERELPGLVPGVCVKNLVKIFEHSGRPAVDC

PF00005 // ENSGT00760000118965_5_Domain_1 (1079, 1222)

LN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDTIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRAGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQGGSCEGTC-SCASKGFSV-
RCPARVEEITPEQVLD--GDVNELVDVVCHHVPEAKLVESIGQEVIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDCDSGL-------------------
LFAGGTQQKKECVNLRHPCLGPSKKARESTQGSNTCCP-QQATHTEGQLPSEPE-QPCIP
LNTGVRLALQHVQALLVKRFHHTVRSHKDFLAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGQQYTFFSMDEPSSERLAVLAESLLNKPGFGNRCLKE----------AWLR-E
DPCSN--ATPWKTPSVSLNVTHLFQQQKWTPSNPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQGSTEILQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLLVLPISGEALVGFLSDLGQIMNVSGGPITREVSREMS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLRHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPADRHPEEHGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSSTTYWLTNFFWDMMNYAV
SAGLVVGIFIGFQKKAYTSTQNLPALIALLMLYGWSVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNALLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEYTSNPFQWDMIGKNLVAMAVEGVLYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAKEPI-
-------VDEDDDVAEERKRIMSGGNKTDILKLSELTKVYSGSSTPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQRMGYCPQFDAIDDL
LTGREHLYLYARLRGIPTEEIERVANWGIQSLGLSPYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSLIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNLVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDVSLHPRAAGARQAK------------------------------------
----------------------------

-------------------------------------MGFLRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNMNNPCF
QNPTPGESPGTVSNYNNSI-----------LARVYRDFQELFMDIPEAQHLGQVWAELRT
LSQFMDTLRTHPERFAGRGLQIRDILKDEETLTLFLTRNIGLSDSVAHLLVNSQ-VRVEQ
FAYGVPDLELTDIACSEALLQRFIIFSQRRGAQTVRDALCPLSQVTLQWIEDTLYADVDF
FKLFRVLPTLLDS-SSQGINLRFWGGILSDLSPRMQKFIHRPSVQDLLWVSRPLLQNSGP
ETFTQLMSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPAYSYD-KRTTS
FCNSLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAAQR-ILKNANSTFEELDRVRKL
VKTWEEVGPQIWYFFEKSTQMTVIRDTLQHPTVKDFINRQLGEEGI-TTEAVLNFFSNGP
QEKQADDMTSFDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRA-LSLLEEN
RFWAGVVFPGM-YPWASSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAY

PF12698 // ENSGT00760000118965_5_Domain_0 (667, 917)

LQDMVEQGIVKSQTQAEPPIGVYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMALSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFATATIMQCFLLSTLFSKASLAAACSGVIYFTLYLPHVLCFAWQ
DRMTADLKTT----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HPEGMNDSFFERELPGLVPGVCVKNLVKVFEPSGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVC-SCTSKGFST-
RCPTRVDEITEEQVLD--GDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGS-------------------
MFVGGAQQKREQAGLRHPCSAPTEKLRQHAQAPHTCSPGQV-DPPKGQPS-PEPEDPGVP
FNTGAWLILQHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPNNEHLEVLADVLLNRPGFGNRCLKE----------EWLP-E
YPCIN--ATSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPALPISGEALVGFLSDLGQMMNVSGGPVTREASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETTDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPRDRDPEEYGITV-ISQPLNLTKEQLSDITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSC
ANLFIGINSSAITFVLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSVNPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--AEPAREPV-
-------FDEDDDVAEERQRVMSGGNKTDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALT
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGASWQAKLEEKSGRLQTQEPLPTGS-EQLAN----GSNPTAA
E-DKHTRSPQ------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGVLPWLQGIFCNMNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVFQDFQELLIDAPENQHLGQIWRDLQT
LSRLMDTLRTHPERIAGRGIQIRNVLKDEETLTLFLRKNIGLSNSVAHLLVNSQ-VRVQQ
FAHGVPDLVLKDIACSEVLLERFIIFSQRRGAHTVRDALCSLSQGTLQWMEDTLYANVDF
FKLFQVLPTLLDS-GSQGINLRFWGRILSDMTPRIQEFIHQPSVQDLLWVTRSLLQNRGP
ETFTELKGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGMDSTRKDPSYSYD-KRTTP
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERLRKL
IKAWEEVGPQIWYFFDNSTQMTMIRDTLEHPTVKDFLNRQLGEDGI-IVEAMKSFLYKGP
QENQADDITNFDWRDIFNITDLSLRMAGQYLECLVLDKFESYDDEIQLTQQA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQARKEAPIGVYLQQMPYPCFVDDS-FMIILNRCFPIFVVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSVMSMSIFLLTLFIMHGR
ILHYSDPFIIFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DQMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPMEGDEFSFLLS
MQMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1078)

YL-DQVFPGNYGTPLPWYFLLQESYWLSGEGCSTREERTLEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGMNDSFFEHELPGSVPGVCVKNLVKIFEPSGRPAVD

PF00005 // ENSGT00760000118965_5_Domain_1 (1078, 1222)

YLN
ITFYENQITAFLGHNGAGKTTTLSILTGLMPPTSGTVLIGGKDIETNLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMETMLEDTGLHHKRNKEAQNLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRAGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPFFLKNCFGTGFYLTLVRKMKTIQSQGGRCEGTC-SCASKGFSV-
RCPARVDEITPEQVLD--GDVNELMDVVCHHIPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLPDLGLSSFGISDTPLEEIFLKATEESDSGL-------------------
LFAGSTQQKREHVNLRHPCLGPSKKDRQPTQGSNICSL-EQAAHPEGQAPPEPE-EPNIP
LNTGMRLILQQVQALLVKRFHHTVRSHKDFLAQIVLPATFVFLAQMLSIIVPPFGEFPAL
TLHPWIYGHQYTFFSMDEPGSERLAVLADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNVTHLFQKQKWTPSNPSPSCTCSTREKLTMLPECPEGAGGLA
PPQRTQGSTEILQDLSRRNISDYLVKTYPALIRNSLKSK----------FWV--NEQRYG
GISIGGKLLVLPITGKALVGFLSDLGQIMNVSGGPITREASREMS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNVKVW
FNNKGWHALVSFLNVAHNAILRASLPQDRHPEEHGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLTQERVTKAKHLQFISGVSSTTYWLTNFFWDIMNYAV
SAGLVVGIFIGFQKKAYTSTENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLARFNAMLRKLLIIFPHFCLGRGLIDLAVSQAVTDV
YAWFGKEHSSNPFQWDMIGKNLVAMAVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2151)

LVQHHFFLTRWYMVAEPAKEPI-
-------VDEDDDVAEERQRITSGGNKTDILRLNELTKVYSGSSSPAADR

PF00005 // ENSGT00760000118965_5_Domain_3 (2151, 2292)

LCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGETTVTSGDATVAGKSILTNIFDVHQRMGYCPQFDAIDDL
LTGREHLYLYARLRGIPAEEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSLIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNLVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGARQQAKVLLLLSLR--ALLE-----------EPLSIGSSEP
--LASI-SDPAAAGNKHMRSCS------

-------------------------------------MNFFRQ-VRLLLWKNWILRKRQK
LRFLVELVWPLTLFLALVWLRKANPLYRQHECHFPNKAMPSAGTLPWLHGIFCNMNNPCF
RSPTHGEGPGVVSNYNNSI-----------LARVYKDAQELLLEAPEVRDLGRIWEELII
MTQFMETMRTNPERIAGRGIRILDILKDGETLTSFLLENVGLTDFVVYQLINAQ-VRPEQ
FAYGVPNLTLKDIACSEMLLDRFIIFSSRRGLPSVHKAMCALSQDSLQRVEDALYANVDF
FKLFQLLPTVLDR-NSPGADLKAWGRVLSNVSQTVQKLVRKPSVQDLLRVLQPFVQDGRP
ESLGHLVSSLSDLFCGYPEGGGSRVLSFNWYEDNNYKAFLGIDTTRKKSGYLYD-NTTTP
FCNALIQNLESNPLTKIAWSAVKPLLMGKILFAPDSPSVRE-IIKNANSTFEELERLQLL
TKAWEEVGPQLWYFFQNSLQMNMIRDSLKHPTVREFLNSQMGAEGF-TAEHIINFLHNGS
SGSREKGMVDFDWRNIFSAVDQVLRLLSQYLQCLTLDKFEGYLDETQLTPQA-LYLLEEN
KLWAAVVFPDL-EPTTSNLPPHVTYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDLRYI
WGGFAYLQDMIERGIIETQTSTEVPLGIYLQQMPYPCFVDDV-FMITLNRAFPIFMVLAW
IYSVSMTVKSIVLEKEMRLKEAMKNRGITNGVIWCTWFLDSFSMMAVSTFLLTALIMHGQ
VLHYSNPLLFFLFLLTFTTATIMQCFLFSTFFSKANLAAACSGVIYFTLYLPHIVCFVWQ
DRLTVNLKIL----ASLLSQVAFGFGTEYLSRYEEQGLGLQWGNIRTSPLEGDEYSFLFS
INMMLFDAFLYGILSWYL-DNVFPGDYGLPQPWYFPVLESYWLGQ---------------
--SEGCVDQKTMEREKNESNT---NKSEEPEKT---------------------------
---------------------EEVNTFFEPEPTGLIPGVCIQNLVKIFANRPKPAVDGIN
ITFYEGQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTMSILTGLFPPTSGTVLVGGLDIQTHMDSIRHRLGMCPQ
HNILFNHLTVAEHILFYSQLKGRSREEAEQELETMLEDMGLTHKRNEEAQNLS--GGMQR
KLSVAIAFVGEAKVVVLDEPTSGVDPYSRRSIWDLLLKYRPGRTIILSTHHMDEADILGD
RVAIISQGKLFCSGSPVFLKNCFGSGFYLTLVRKMRTTKMGRA---------TCSCSC-S
SCMHRGEEGAPEMELD--GDLNELAEVIHHHIPEAKLIESIGQELIYLLPNKNFKQRSYA
SLFRE-LEETLDDLGLSSFGVSDTPLEEVFLKVTAEADPEMQKT----------------
---GDTQENGSA---LGKTPTENKPAEQTALKTNDT-----SRMPVGRAGDQNE-GKGSR
QYKGFQLVHQQIKALLIKRFHRASRSHKDFLAQRVLPLDFVITFEGGQ-LVVPYGFPSLV
AM--CITKFLSYSLSNERPGNEQMVSLTHAFLNKPGFGIRCMKN----------QPLL-S
YPCNNM-PTAWDTPAVHPNLSSLLLSQQWSPENPSPSCKCSTHKKLTMLPECPAGAGGLP
PPQRVQRSTEILQDLTHRNISDFLVKTYPTLIKGSLKSK----------YWV--NEQRYG
GISIGGRLPVLHVSGDQIVNFLSDLGRMMNVTGGQTSLAAAKEIPNFLKYMETEDNIKVW
FNNKGWHAMVSFLNVANNAILRANLRTGQDPEEHGITA-INHPLNLTKEQLSEVTVLTTS
VDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPVTYWLTNFMWDIVNYAL
SAGMVVAIFVGFNKKAYASPTNLPVLVSLLLLYGWAVIPMMYPASSFFSIPSTAYVALSC
INLFVGINSSAITFILELFENNPSLLKFNKTLKNVLLVLPHFCLGRGLIDLAMNQAVTEV
YARFGEEHISDPFQWDFVGKNLVAMALQGVVFFFLNLFMQHHLFSTRWF--AQTAMSPI-
-------INEDEDVAEERKRIMNGGNKTDILQLQELTKIYAGQHKPAVDRLCVGIRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTDVTSGDAVVAGNSILTHISNVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIKRVAEWGIQKLGLPMYADHLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQSRRLLWDSIVGVLRDGRAV-----VLTSHSM-----------
EECEALCTRLAIMVQGTFKCLGTIQELKYKFGDGYIVTLKIKAPKSGLPPDPAPAEKFIR
INFPGSLQREKHYNMLQYQICSSSLAKIFRLIISNKENLHIEEYSVSQTTLDQ--VFVNF
AKQQME-DEEIPLHPRAAGASRETKV----------------------------------
----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------RPSVQDLLWVTRPLLQNGEP
ESISQLMRILSELLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDPSRKDPVYSYD-KRTSK
FSFRPLGDSSSTMLLREAWKGATELMMGATILMVPSICTARLIVTYKTCVFIELLKDIIL
KSAYRDLIPSLWYFISTSRKLHYVAAHLILADVTASVACQLGTSII-SIVSVLSYLNVIH
FAIGKDSLVGCSQREELGLLDNSRFVLSYYLQCLILDKFESYDDEIQLTHRA-LSLLEQN
RFWAGVVFSDI-SPWNSLPPRHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVEDFRYI
WGGFAYLQDMIEQGIIRSQTQAEVPIGIYLQQMPYPCFVDDVSFMITLNRCFPVFMVLAW
IYSVSMVVKSIVLEKEMRLKESLKNRGVSNAVIWCTWFLDSFSVMAMSTVLLTTFIVQGQ
VLHYSNPAILLLFLLVFSGTTITQCFLFSAFFSKANLAAACSGLLYFTLYLPHILCFAWQ
EHMTAQIKVV----LSLLSPVAFGFGTEYLSRYEEQGIGLQWDNIGKSPMEGDEFSFQLS
IKMMLIDAILYGFLAWYL-DQVIPGDYGKPLPWYFLLQESYWLGGEGCSTREERALEKTE
PVTEEMEDPD--------------------------------------------------
---------------HPGERHGINDTFFERELPGLVPGVCVQNLVKVFDFQSKPAVDRLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTMSILTGLIPPTSGTVLIGGKDIETHMDSIRQDLGMCPQ
HNILFHYLTVAEHILLYAQLKGKSRKEAQLEMETMLEDTGLHHKRNEEAQNLS--GGMQR
KLSVAIAFVGDAKVIVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSHGKGCEKTC-SCTSKGPS-I
SCP-KVEEITAEQVLD--GDVNVLIEMIHHHVPEAKLVECIGQELIFLLPNKDFKQRAYA
SLFRE-LEETLPDLGLSSFGISDTPLEEIFLRVTGDSESGA-------------------
LFVGDSYQTGPSFSFRNPGLNSSEKTTRGSQTLNGSPTPEPIPPAEGQASKEAE-DAGMP
LNKGPQLLCQHVQALLIKRFYRAARSHKDFLAQIVLPAGFVCMALLLAISIPPFGEYPAL
RLHPWIYGQQYTFFSSEQPDNEQLSTLTEVLLNKPGFGNRCLRD----------ASLP-N
YPCGNS--TSWKTPSVSPNMTHLFQNQKWTADNPSPACKCSTQEKLTMLPECPEGAGGLL
PPQRVQRSTEILQDLTNRNISDFLVKTYPTLIRSSMKSK----------YWV--NEQRYG
GISIGGKLPVFCITGEEIVGFLRDLGQFMNVSGGPATQEAAKEMSNFLKYLETENNIKVW
FNNKGWHAMVAFLNVANNAILRASLPKDKDPEDFGITL-INQPLNLTKEQLSDITVLTTS
IDAMVAICVIFAMSFVPASFVLYLIQERVSKAKHLQFVSGVSPTTYWVTNFLWDMVNYAV
SAGIVVGIFVGFQKRAYTSPSNLPALIALLFLYGWAVTPMMYPASLLFDVPSTAYVALSC
ANLFIGINSTALTFVLELFENNSALLTLSAVLRKALLIFPHFCLGRGLIDLALNQAVTDV
YAAFGEEHFSDPFQWDIVGKNLVAMAVEGGVYFILNLLLQHHVFLTRWI--ADPTKQPVA
EPTKQFMADEDDDVAEERQRILRGGNKTDILRLNELTKIYSGTTSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDIPVTSGDAVVAGKSILTQISEVHQNMGYCPQFDAVDDL
LTGREHLYLYARLRGVPTEDIKRVANWCIQSLGLSPYADRLVGSYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRLLWNTIVSIIWQGRAV-----VLTSHSM-----------
EECEALCTRLAIMVKGSFQCLGTIQHLKYRFGDGYIVTMKIRPPKAGLLPDLNPAEQFLQ
ANFPDSVQRERRHNMLQYRISSSSLARIFQLLISNKDSLYIEEYSVTQTTLDQ--V----
------------------------------------------------------------
----------------------------

-------------------------------------MGFARQ-IKLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNVNPLYSKHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTAGESPGIVSNYNNSIHVFNDEAHSYSLARVYRDFQELLMDAPESQHLGQVWKELCT
LSQLMNTLRMHPERIAGRGIRVRDVLKDEETLTLFLVKNIGLSDSVVYLLVNSQ-VRPEQ
FARGVPDLMLKDIACSEALLERFLIFPQRRAAQTVRGSLCPLSQGTLQWMEDTLYANVDF
FKLFHVFPRLLDS-SSQGMNLRSWGRILSDMSPRIQEFIHRPSVQDLLWVTRPLVQTGGP
ETFTQLMGTLSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-ERTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPATRR-ILKNANSTFEELERVRKL
VKVWEEVGPQIWYFFDKSTQMTMIRDTLENPTVKAFWNRQLGEEGI-IAEAILSFLYKGP
REGQADDVGNFNWRDIFNITDRALRLANQYLECLILDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDM-HPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRS

PF12698 // ENSGT00760000118965_5_Domain_0 (679, 917)

QAREEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNRVIWCTWFLDSFSIMSMSICLLTIFIMHGR
ILHYSNPFVLFLFLLAFSIATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRITADMKMA----VSLLSPVAFGFGTEYLARFEEQGVGLQWSNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERAWEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGINGCFFERELPGLVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYESQITAFLGHNGAGKTTTLSIMTGLLPPTSGTVLVGGKDIETNLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWDEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGVQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1792)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADILGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKTIQSQGRGCEGTC-SCASKGFSV-
RCPACAEPMTPEQVLD--GDVNELMDMVRHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDLDSGH-------------------
LFAGGTQQKRENINLRHPCLGPSEKARQTPQGSSSHPG-EPAAHPEGQPPP--EQEGHSR
LNSGARLVVQHVHALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSLIIPPFGEYPAL
TLHPWMYGQQYTFFSMDQPDSEWLSALADVLVNKPGFGNRF----------------P-M
LPCCNTNSCPGRTPSVSPDVTHLLQQQRWTADQPSPACRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNVSDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAPRITGEALVGFLSDLGQLMNVSGGPMTREAAKEMPAFLKQL

PF12698 // ENSGT00760000118965_5_Domain_2 (1792, 2078)

ETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLHKDKNPEEYGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYTV
SAALVVGIFIGFQKKAYTSSDNLPALVALLMLYGWAIIPMMYPASFLFDIPSTAYVALSC
ANLFIGINSSAVTFVLELFENNRTLLRINAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWDLIGKNLAAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQYQFFFSRWT--TEPAKEPV-
-------IDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTPVTSGDATVTGKSILTNISDVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVTNWSIQSLGLSLYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIMGIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIRSPKDDLLPDLGPVEQFFQ
GNFPGSVQRERHHNMLQFQVSSSSLARIFRLLVSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-TYDLPLHPRAAGASRHAKVPLPPFPCPLLGA----DP-WLKDPADT-LGLQGP
QTCLLQRVPPIAALTSSL-PCLTCLGQR

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQAILNFLYKGP
QESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMNVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLVDLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFTGGAQQKRENINPQHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRFPTRPCPNKTSSPGRTRR-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVIPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQVPLLLTQ-----------------STA--------
----------------------------

-------------------------------------MGFARQ-TQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGVLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSV-----------LAKVFRDFRELLVDAPESQRLGGVWTDLRT
LFQLMDTLQTHPEKVAGRGIQIRDILKDEETLTLFLMRNIGLSNSVAYLLVNSQ-VRVEQ
FAHGVPDLALKDIACSEALLERFIIFNQRRGANIVRDALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDR-GSQGINLRSWGRTLADVSPRIQQFIHRPSVQDLLWVIRPLLQNRGP
ETFAQLMGTVSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KKTTP
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFSPDSPAARR-ILKNANSTFEELERVRKL
VKAWKEVGPQIWYFFNNSTQMMMVRDTLEHPTVKEFLNRELGEDGL-SVEAIVNFFYKGP
RVGQADDTTDFDWRDIFNITDHFLRLADQYLECLVLDKFESYDDENQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVEYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMIEQGITRSQAGVETPIGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKDIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPSIVFLFLLVFATATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DQMTAKLKKAVVRDLDLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPMEGDEFSFLLS
MQMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1079)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALERTE
PITEEMEDPE--------------------------------------------------
------------------HPEGMNDSFFERELPGLIPGVCVKNLVKIFEPSRRPAVDC

PF00005 // ENSGT00760000118965_5_Domain_1 (1079, 1222)

LN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETHLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRAGRTIIMSTHHMDEADLLGD
RVAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQGGSCEGTC-SCASPGFSV-
RCPARVDEITPEQALD--GDVNELMDVVCHHVPEAKLVECIGQEVIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGL-------------------
LFSGGTQHKREHVNLRHPYLGLSKKARQPAEDSNSCSP-EQEAHPEGQPPPEPE-QPSFS
LNTGVRRVLQQVQALLVKRFHHTVRSHKDFLAQIVLPATFVLLALMLSMIVPPFGEFPAL
TLHPWIYGQQYTFFSMDEPGNERLAVLADVLLNKPGFGNRCLKK----------AWLL-E
YPCGN--STPWKTPSVSPNITHLFQKQKWTPSNPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQGSTEILQDLTNRNISDYLVKTYPSLIRGSLKSK----------FWV--NEQRYG
GISIGGKLLVLPVTGEAVVAFLSDLGQIMNVSGGPITREVSREMS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLHEDRHPEEHGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFFWDIMNYAV
SAGLVVGIFIGFQKKAYTSAQNLPALIALLMLYGWAVTPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLLRINALLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFRWNMIGKNLVAMATEGVAYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAREPI-
-------VDEDDDVAEERKRITGGGSKTDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGIRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQRMGYCPQFDAVDDL
LTGREHLYLYARLRGVPAEEIERVANWGIQSLGLSFYADRLVGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSLIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNLVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGARQQGKVATALSQHWCRQML-----------AQLALCISGA
PMLRPP-PHPQHILTTHCPFCALGFMHQ

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLILIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELFMNAPESQHLGRIWTELCI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLSLFLIKNIGLSDSVVYLLIHSQ-VRLEQ
FAHGVPDLALKDIACSEALLEHFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQQFIHRPSVQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDTTRKDPIYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYAPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANFDWRDIFNVTDRTLRLVNQYLECLVLDKFENYDDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKENLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKANLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGSSPTEGDEFSFLLS
MQMMLLDAAIYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1105)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREYERN----
------------------------------------------------------------
------------------------------------RGVCMEPPVRTMNR----------
--------------QQRSNYSEES

PF00005 // ENSGT00760000118965_5_Domain_1 (1105, 1222)

ILTGLLPPTSGTVLIGGRDIETSLNAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1789)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRRGSEGTC-SCASKGFSTT
TCSAHVSDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPSKNFKQRAYA
SLFRE-LEETLVDLGLSSFGVSDTPLEEIFLKVTEDSGSGP-------------------
LFAGGTQQKRENVNLRHPCLGPRENAGQIPQDSNDCSPGATAAHPEGQPPPEPE-RPGPQ
LNTGAWLVLQHVQALLLKRLQHTIRSHKDFLAQIVLPAAFVFLALMLSIIIPPFGEYPAL
TLHPWMYGHQYTFFSMDEPGSEQLTVLADVLLSKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNVTQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPVTREASKEIPAFL

PF12698 // ENSGT00760000118965_5_Domain_2 (1789, 2078)

KHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDALVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYTV
SAALVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFESNRMLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YTRFGEKHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2151)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRVITGGNKTDILRLHELTKIYPGTSSPAVDR

PF00005 // ENSGT00760000118965_5_Domain_3 (2151, 2292)

LCIGVRAGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYFYARLRGIPAEEIEKVANWSIKSLGLTVYADCLAGMYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQVPLLLLQ-----------------STA--------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNVNNPCF
QSPTPGESPGTVSNYNNSI-----------LARVYRDFQDLLRDAPESQQLGRVWTELRT
FFQLLETLRTHPERTAGRGIRVREILKDEEILVLFLKRNIGLSDSVVHLLVNSQ-VRPEQ
FAHGVPDLALKDIACSEALLDRFLIFSQRRGAQTVRGALCSLSQGTLQWMEDTLYANVDF
FKLFRVLPTVLDS-RSQGIDLRSWGRILSDMSPRIQEIIHAPSTEVILQSTQTHTARHNG
--KIIYFFFVKDVMCIFELTSGCQAFSLYRRQSLLPRAGAGAWTGRGTAEWSLDSIVAAP
FCNALIQNLESSPLTKIAWRAAKPLLMGKILFTPNSPATRR-ILKNANSTFEELERLRNL
VKAWEEIGPQIWYFFDKSPQMHMIRNTLRNPAVKGFLDRQLGEEGL--AEALLNFLHNGP
QESQADDTANFNWRDLFNVTDRTLHLVHQYLECLVLDKFESYDNEVQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHIKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAYLQDMVEQGITRSQVPAGAPLGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRLTAELKKA----ASLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPMEGDEFSFLLS
MKMMLFDAALYGLLAWYL-DQVFPGDHGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPGGTNDSFFERELPGLVPGVCVKNLVKIFEPFGRPAVDHLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTAGTVLIGGKDIETSLDAIRRSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGEAKVVVLDEPTSGVDPYSRRSIWDLLLKYRPGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMRNIQSQGGGCEATC-SCASKCISS-
RCPARTDEMTSEQALD--GDVNELVDVVQHHVPEATLVECIGQG----------------
----E-LEETLADLGLSSFGISDTPLEEIFLKVTEDADSGL-------------------
-FAENTQAMRE--YLRHPCLGPSGKAEESAQA----------TASEGSPSPEPE-GTGVP
LNTGVRLILQHVQALLIKRFHHAIRSHKDFLAQIVLPATFVCLALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGNERLATLADVLLNKPGFGNRCLKQ----------EWLP-G
YPCGN--STAWKTPSVSPNITHLFQQQIWTPDNPSPSCRCSTREKLTMLPECPRGAGGLP
PPQRTQRSTEILQDLTDRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPFTGKALVAFLNDLGHLMNVSGGPVTRKATQEMSDFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPPDRNPEEYGVTV-ISQPLNLTKEQLSEVTVLTTS
VDALVAICVIFAMSFVPASFVLYLIQERVSKAKHLQFISGVSPTTYWLTNFLWDIMNYAV
SAALVVGIFIGFQKKAYTSPDNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNALLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFQWDLLGKNLVAMAVEGVVYFLLTLLIQHHFFLTRWI--AEPAKEPI-
-------VDEDDDVAEERQRIISGGNKTDILKLNELTKIYSGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAKEIGKVANWCIQSLGLSLYVDRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIRSPKDDVLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQYQVSSSSLARIFQLLISHKDSLFIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGANQQVKV----------------------------------
----------------------------

-------------------------------------MGFPRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSHHQCHFPNKAMPSAGVLPWLQGIFCNMNNPCF
QNPTPGETSGIVSNYNNSI-----------LARVYRDFQELFVDTPEVQQLGQVWAELRT
LSQLMDTLRTHPERFAGRGLQIRDILKDEDTLTLFLTRNIGLSDSVAHLLISSQ-VRVEQ
FAYGVPDLELKNIACSEALLQRFIIFSQRWGAQTVRDALCPLSQMTLQWIEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRFWAGVLSDMSPRLQKFIHRPSVQDLLWVTRPVLQNSGP
ETFTQLMSILSDLLCGYPEGGGSRVFSFNWYEDHNYKAFLGIDFTRKDPTYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAVRR-LLKNANSTFEELDRVRKL
VKAWEEVGPQIWYFFDKSTQMTMIRDTLEHPAVKDFINQQFGEEGV-TTEAILNFFPSGA
RETQAEDMPDFDWRDVFNFTDRVLHLANQYLECLVLDKFESYDDEVQLIQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQTQADVPIGVYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHVLCFAWQ
DRMTSDLKTI----VSLLSPVAFGFGTEYLVRFEEQGLGLQWNNIGKSPVEGDEFSFLLA
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HPEGMSDSFFERELPGLVPGVCVKSLVKVFEPGSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLT
ITFYESQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLESVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAILSQGRLYCCGTPLFLKNCFGTGFYLTLVRKMKNIQNQRGGCEGAC-SCTSKAFPT-
RCPARVDEITEEQVLN--GDVKELTDLVYHHVPEAKLVECIGQELIFLLPNKDFKQRAYA
SLFRE-LEETLSDLGLSSFGISDTPLEEIFLKVTEDSDSSS-------------------
MFAGSTQQKREHVDLRHPRSAPTEKVRQPAQGSHPCSPGQV-DPSKGQSS-PRPEELGSP
FYTGARLILQHVQALLIKRFHHAVRSHKDFLAQIVLPATFVFLALLLSVVVPPFGDFPAL
TLQPWMYGHQYTFFSMDEPSNEHLTVLADVLLNKPGFGNRCLKK----------ERLL-E
YPCGN--STSWKTPSVSPNITHLFQKQKWTMAHPSPSCMCSTREKLTMLPECPEGAGGLP
PPQRTQRSMEVLQDLTGRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPVTGEALVGFLSDLGQMMNVSGGPVTREASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETKDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDKDPEEYGITV-ISQPLNLTKEQLSEITMLTTS
VDVVIAICVIFAMSFVPASFVLYLIQERVTKAKHLQLISGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFAGFQKKAYTSPDHLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSTAITFILELFENNQPLLRLNAMLRKLLVVFPHFCLGRGLVDLALSQAVTDV
YAQFGEEYSSDPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQYHFFFTRWV--AEPAREPI-
-------FDEDDDVAEERQRITSGGSKTDILWLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTSMSDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEDIEKVANWGIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNTIISIIRDGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKSKFGDGYIVTMKIKSPKDGLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVSF
AKQQTE-TYDLPLHPRAAGASWQTKLEGKTGQPETQEPLPTGTTEQLVN----ENSPAAA
E-GKHTRRPQ------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLLLIWLRNVNPLYSQHECHFPNKAMPSAGMLPWLQGMFCNVNNPCF
QSPTPGESPGIVSNYNDSI-----------LARVFRDFQELLMDVPESQHLGHVWKELQT
FSQLMDTLRTHPERVAGRGIRIRDVLKDEETLTLFLMKNIGLSDSVVYLLVNSQ-VRPEQ
FAHGIPDLTLKDIACSEALLERFLIFSQRRGAQTVRDAMCSLSQGTLQWVEDTLYANVDF
FKLFRVLPTLLDS-SSPGINLRSWGRILSVMSSRIQEFVHQPSVQDLLWVTRPLMQAGGP
ETFTQLMSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVYSYD-KRTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILQNANSTFEELERLRKL
VKAWEEVGPQIWYFFDKSTQMTMIRDTLQNPTVKDFLNSQLDEEGI-TVETVLNFLYKGP
QENQADGVANFDWRDVFNITDRTLRLASRYLECLILDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSALPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMIEQGITRSQAQVEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWSTWFLDSFSIMSMSIFLLTTFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKMA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWGNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGNYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGTHDSFFERELPGLVPGVCVKNLVKIFEPYSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITALLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGGAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1792)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRTGYEGTC-SCASQGFST-
RCPAHIDEISPEQVLD--GDVNELMDMVQHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLAELGLSSFGISDTPLEEIFLKVTEDSDSGL-------------------
LFAGGAPQKRENASLRHP----MEKARQIPLGSNGCSA-EPAPHPEDHSSSK--PEERSR
FNTGAQLIIQHMQALLVKRFHHTARSHKDFLAQIVLPATFVFLALMLSIIVPPFGEYPAL
ILHPWMYGQQYTFFSLDQPGSEQLAALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNITHLFQKQKWTPDDPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRIQHSSEILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLPITGEALVGFLSHLGQIMNVSGGPITREASKEMPAFLKHL

PF12698 // ENSGT00760000118965_5_Domain_2 (1792, 2078)

ETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLHKDKNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFIPASFVLYLIQERVNKAKHLQFISGVSPITYWLTNFLWDIMNYSV
SAALVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDIPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLLRFNAMLRMLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWNLIGKNLVAMAVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLIRWV--AEPAKEPI-
-------IDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQSMGYCPQFDAVDDQ
LTGREHLYLYARLRGVPADEIERVTNWSIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNIIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKEDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFRLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQHTE-IHDLPLHPRAAGASRQAKV----------------------------------
----------------------------

-------------------------------------MGFARQ-IKLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNVNPLYSKHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTAGESPGIVSNYNNSI-----------LARVYRDFQELLMDAPESQHLGQVWRELRT
LSQLMNTLRMHPERIAGRGIRIREVLKDDEMLTLFLVKNIGLSDSVVYLLVNSQ-VRPEQ
FARGVPDLMLKDIACSEALLERFLIFPQRRAAQTVRGSLCSLSQGTLQWMEDTLYANVDF
FKLFHVFPRLLDS-RSQGMNLRSWGRILSDMSPRIQEFIHRPSVQDLLWVTRPLVQTGGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-ERTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPATRR-ILKNANSTFEELERVRKL
VKVWEEVGPQIWYFFDKSTQMSMIRDTLENPTVKAFWNRQLGEEGI-TAEAVLNFLYNGP
REGQADDVDNFNWRDIFNITDRALRLANQYLECLILDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDM-HPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEHGITRSQAQEEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNRVIWCTWFLDSFSIMSMSICLLTIFIMHGR
ILHYSNPFILFLFLLAFSIATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRITADMKMA----VSLLSPVAFGFGTEYLARFEEQGVGLQWSNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------YPEGINDCFFERELPGLVPGVCVKNLVKIFEPYGRPAVDRLN
ITFYESQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSIMTGLLPPTSGTVLVGGKDIETNLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWDKAQLEMEAMLEDTGLHHKRNEEAQDLS--GGVQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADILGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRRMKTIQSQGRGREATC-SCASKGFSV-
RCPACAEAITPEQVLD--GDVNELTDMVHHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDLDSGH-------------------
LFAGGTQQKRENINLRHPCSGPSEKAGQTPQGSSSHPR-EPAAHPEGQPPP--EREGHSR
LNSGARLIVQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSLIIPPFGEYPAL
TLHPWMYGQQYTFFSMDQLDSEWLSALADVLVNKPGFGNRCLKE----------EWLP-E
FPCGN--SSPWKTPSVSPDVTHLLQQQKWTADQPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQDLTDRNVSDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISVGGKLPAPPFTGEALVGFLSDLGQLMNVSGGPMTREAAKEMPAFLKQLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLHKDKNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYTV
SAALVVGIFIGFQKKAYTSSENLPALVALLMLYGWAVIPMMYPASFLFDIPSTAYVALSC
ANLFIGINSSAITFVLELFENNRTLLRINAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWDLIGKNLAAMAVEGVVYFLLTLLIQYQFFFSRWT--TEPAKEPI-
-------TDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTAVTSGDATVAGKSILTNISDVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVTNWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIMGIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIRSPKDDLLPDLGPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFRLLVSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-TYDLPLHPRAAGASRQAKEVDKGNSAPQG------------------------
----------------------------

-------------------------------------MGFPRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHQCHFPNKAMPSAGTLPWLQGIFCNLNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVYRDFQELFMDTPEIQHLGQIWTELRT
LFRLMDTLRTHPERFAGRGLQIRDILKDEETLTLFLTRNIGLSDSVAHLLVNSQ-VRVEQ
FAYGVPDLELKSIACSETLLQRFIIFSQHRGAQTVRDTLCPLSQVTLQWIEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRFWGGILSDMSPRLQKFIHRPSVQDLLWITRPVLQNSGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPTYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAVRR-LLKNANSTFEELDRVRKL
AKAWGEVGPQIWYFFEKSTQMTMIRDTLEHPTVKDFINRQLAEEGI-TTEAILNFFRSGP
RESQADGMTNFDWRDVFNITDRFLRLANQYLECLVLDKFESYDDETQLIQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAYLQDMIEHGITRS

PF12698 // ENSGT00760000118965_5_Domain_0 (679, 917)

QTQAEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHVLCFAWQ
DRLTADLKTV----VSLLSPVAFGFGTEYLVRFEEQGLGLQWDNIGKSPMEGDEFSFLLS
MEMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HPEGMSDSFFERELPGLVPGVCVKNLVKVFEPCSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGAC-ICTSKAFST-
RCPARADEITEEQVLD--GNVKELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLTDLGLSSFGISDTPLEEIFLKVTEDSDSGS-------------------
MFAGGTQQNREHVSLRHPCSAPTEKVRQPAQGSHTCSVGQV-DPSKGQPS-PEPEEPSAP
FNTGARLILQHVQALLVKRFHHAVRSHKDFLAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPSNEHLAVLADVLLNKPGFGNRCLKK----------EWLP-E
YPCGN--STPWKTPSVSPNVTHLLQKQKWTAADPSPSCMCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGTLPAIPITGDALVGFLSDLGQMMNVSGGPVTREASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETKDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDVVLAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPATYWLTNFLWDITNYAV
SAGLVVGIFIGFQKKAYTSADNLPALAALLMLYGWAIIPMMYPASFLFDVPSTAYVALAC
ANLFIGVNSSAITFVLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYFSNPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAREPI-
-------FDEDDDVAEERQRITSGGNKTDILRLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEDIEKVANWGIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVASSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--ASPPR
VPSAS---RLCPLHDST-------------------------------------------
----------------------------

-------------------------------------MRFSAK-VKLLLWKNWTLRKRQK
LRIFVELVWPLSLFFILVWLRNANPLYGQHECHFPNKAMPSAGLLPWLHGIFCNTNNPCF
KSPTRGESPGVVSNYNNSI-----------LARAYSDAQEVLLEKPEIRHLSRMWKELYT
MSNLMDTLRTNPGKVSGRGIRVKDILKDDETLTLFLLRDIGLSDSVVYQLINAQ-IRIEQ
VSFPVDPLILIVVHCTGSYLPGFFMSLSNARNATVRNSMCVLSQQRLQRIEDVLYASIDF
FKLFEILPTVIDY-SSRGIDLRFWGKVMSNLSESLKELVQKPSIQDLLWVLRPLVQDGGP
TTFTQLINSLSDLFCGYPEGGGARVFSFNWYEDNNYKVFLGVNSTKKETYYLYD-KTTTP
FCNALIQSMESNPATKIAWSAMKPLLMGKVLYSPDSPAVRE-ILKKANSTFEQLERVRQM
GKAWEEVGPQLWNFFHSSVQMNLVRDTIKNPTVKEFLTRQLGDEGL-TADDVINFLYNGN
QDERPEGQVNYDWRNIFNITDHAIRLFNQYMGCLTLDKFEGHDDESHLTHHA-LYLLEEN
KFWAGLVFLDM-FPWTNTLPSHVKYKIRMDIDAVEKTKKIKDRYWDPGPRADPVEDMRYI
WGGFAYLQDMIDHGIIKSQTSTEVPAGIYLQQMPYPCFVDDV-FMITLNRCFPIFMVLAW
IYSISMLVKDIVLEKELRLKETMKNMGVTNDVIWLTRFIDSFTVMTTSTILLTVVIVVGG
VLHYSNPIILFCFLMAFTIATIMQAFLMSVFFSKANLAAACSGVIYFTLYLPHILCFAWQ
DRMTIKLKTL----ASFLSPVAFGFGTEYLSRYEEQGLGLQWGNIRKSPMEGDEYSFLFS
IFMMLLDAFIYWTLAWYI-DHVFPGEYGIPKPWYFPFLATYWCKFEHEFGGDADSIETEL
SIHEHIEENH-IEPTDNQPEALPDGVKEEAEKSVKQDDII--VNKDSSACKHFSLLKSLH
YSRRKKQAKCEKSRVKASTVLFKGNPFFEPEPPGMVPGVYIQDLVKVYENTYKPAVDRMN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

GQITAFLGHNGAGKTTTLSIITGLFPPTSGTVWVRGRDIQTHMDSIRQSLGMCPQ
HNILFRHLTVEEHILFYAQLKGKSRKQAERQAEVMLEDMGIPHKRNDEAQNLS--GGMQR
KLSVALAFVGESKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIILSTHHMDEADLLGD
RIAIVSQGKLFCSGSPLFLKNCFGTGFYLTLVRRMRNIKDTGKKDSASC-QSDCSCPC-S
SCTPKVKENLLEQELD--GDVSGLTELIHHHVPEAKLLESIGQELIYLLPSKDFKFRAYA
SLFRE-LEETLGDLGLSSFGISDTPLEEIFLKVTADSVTGTETPEEEWMLQQRKSR----
TSLGVDNQ-------TTVINIDNKAQGQESSIRKDSHHCKAEKNPPNINDREAD-GRGSR
QIKGTELLQQQFNALIIKRFKHATRSHKDFFAQVFLMASFVLLALVFTLIVPPFGEYPSL
TLHPWIYGQQFVFFSNEQPGNEQMATFSNAFLNSPGLGTRCMKD----------QPLSKK
YQCTNT-SNEWTMPAVSPSVTNMLLSQEWTRDNPSPSCTCSSRSKLMMLPECPEGAGGRP
PPQRIQPSSEIIQDLTERNISDFLLKTYPDLIRSSMKSK----------YWV--NEQRYG
GISVGGKLPVLHVKGGDIVSFFSQVGQMTNVTAGTTTKAISQELQTFLQNLETEDNIKVW
FNNKGWHSMVIFINVANNAILRANLGADKDPEEFGITT-MNHPLNLTKDQLSEVTVLTTS
VDVVVAICVIFAMSFIPASFVLYLIQERVSNAKHLQFVSGVTPAIYWLTNFAWDIINYAI
SVAMVVIIFIAFDKKAYTSSSNLPALIALLFFYGWAVIPMMYPASYLFNVPSTAYVALSC
INLFIGINSSAITFILDLFENNRSLLKFNEKLKDLLLIFPHFCLGRGLIHVFMNDPVKTV
EIKSGEEHVSNPFQWEFLGRNIFAMAVEGVVYFTLNLLIQHRFFFSTWF--SEPPKGLV-
-------EGEDEDVAQERQRVIKGGGKNDILKLKELTKTYPGKQSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDIQVTSGDASVAGYSILQDIADVHQNTGYCPQFDAIDDL
LTGREHLQLYGRLRGVPEDEIDMVADWGIEKLGLGKYADNLTGTYSGGNKRKLSTAIALI
GCPPVVLLDEPTTGMDPQSRRFLWNSIVSIIKEGRAV-----VLTSHSM-----------
EECEVLCTRLAIMVKGTFKCLGTIQHLKYKFGDGYIVTMKVRASKPGLAPDPGPVEKFIQ
TNFPGSVQREKHYNMLQYQLSSSSLARVFQLLISNKDSLNIEEYSVSQTTLDQ--VFVNF
AKQQTE-DEDIHLHPRAAGATRDMKVAPAPPLKKPSQ-----------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNVNNPCF
RNPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMDTPESQHLGQVWTELRS
LSQLLDTLRTHPERVAGRGLQIGDILRDEETLTLFLMRNIGLSNSIARLLVNSQ-VRVEQ
FVHGVPDLQLKDIACSEALLERFLIFSQRRGARTARDALCALSQGTLQWMEDTLYANVDF
FKLFRVLPTVLDS-RSQGIDLRSWGRVLSDISPRIQEFIHRPSVQDLLWVTRPLLQNSGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDCPAAQR-ILRNANSTFEELERVRKL
VKAWREVGPQIEYFFENSTQMTMIRDTLGHPTVKDFVNRQLGEEGI-TTEAILNFFSKGP
RERQADDTTTFDWRDIFNITDRSLRLVSQYLECLVLDKFESYDDEVQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSTPRHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAYLQDMVELGITRSQAQAGAPVGVYLQQMPYPCFVD

PF12698 // ENSGT00760000118965_5_Domain_0 (701, 917)

DS-FMIILNRCFPVFMVLSW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSNPFIVFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWNNMGSSPVEGDEFSFLLS
MKIMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERLLEKTE
PLTEELEDPE--------------------------------------------------
------------------HPEGINDSFFERELPGLVPGVCVNNLVKIFEPGSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLNSIRQSLGMCPQ
HNILYHHLTVAEHILFYAQLKGRSWEEAQLETEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCAGTPLFLKNCFGTGFYLTLVRKMKNMQNQRGGCEGAC-SCAAKGFSA-
RCPARVDEITEEQVLD--GDVNELMGLVRHHVPDAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTADSDSGS-------------------
LFTGGTQQKREYANFRHPGLDPSEKVKQPAEVSHSCCPGQG-THPEGQPS-PEPQEPGTP
LNTGSRLVFQHVQALLIKRFHHTVRSYKDFLAQIVLPATFVFLALMLSVIVPPFGEFPAL
TLHPWMYGHQYTFLSMDEPGSEHLELLADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWQTPAVSANIAHLFQKQKWTADSPSPSCKCSTREKLTMLPECPEGAGGLP
PPERIQRSSEILQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLPISGEVLVGFLSDLGQMMNVSGGPITKEASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETKDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEHGITL-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDMLNYAV
SAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHLSNPFQWDLIGKNLVAMGVEGVVYFILTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--AEPAKEPI-
-------VDEDDDVAEERQRIASGGNRTDILRLNDLTKIYSGSSNPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFRCLGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYHMLQFQVSSSSLARIFQLLISHKDSLFIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGANQQAKVVLV--------PLPAHSLGQG------LLTPQTG
LLQKAPPKPYHHLPSLSYQLSDERLFSQ

-------------------------------------LLFLRVVSKLLCHQDWAHALTSQ
IRFVVELVWPLSLFLVLIWLRNANPLYSQHQCHFPNKAMPSAGMLPWLQGIFCNMNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVYRDFQELFMDAPESQHFGQVWAELRT
LSQLLDTLRTHPERFAGRGLQIRDILKDEETLTLFLMRHIGLSDSVAHLLVNSQ-VRVEQ
FAYGVPDLELKDIACSEALLQRFIIFSQRWGAQTVRDALCPLSQVTLQWIEDTLYANVDF
FKLFRVVRKGCDNKASQDLTLVFWVF------TSGSKFIHQPSVQDLLWVARPILQNRGP
ETFTQMMGVLSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPTYSYD-KRTTS
FCNALIQNLE------------------------------------------------KL
VKAWEEVGPQIWYFFEKSTQMTMMRVRMLTTWEL-------------------EIVHHGS
QHGM-------------------GRRRRAIEICLVLDKFESYDDEVQLIQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVRYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAYLQDMVEQGIIRSQTQAEVPTGVYLQQMPYPCFLLGC-R----------------
-------------------------EHWGSPRNWCVWLWGSGSRNKLL-ITSSLCFQHGR
ILHYSDPFILFLFLLAFSTATIAQCFLLSAFFSKASLAAACSGVIYFTLYLPHVLCFAWQ
DRMTADLKTIVVRMYSL-------------------GLFIVWLNITEVIF----------
LNLFGLGLT----VFSFL-AFLFPGDFGTPLPWYFLLQESYWLGGEGCSTREERALERTE
PLTEEMEDPE--------------------------------------------------
------------------HPEGMSDSFFERELPGLVPGVCVKNLVKVFEPCSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHIMFYARLKGKSWEEAQLETEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1918)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKSIQSQRGGCEGAC-SCTSKGFSS-
RCPARADEITEEQVLD--GDVKELVDLVSHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLTDLGLSSFGISDTPLEEIFLKVTEDSDSSS-------------------
MFTGGMQQRRERGGLRHPCSAPTE-VRQPAQGPHTCFPGQA-DASKGQPSPEPE-EPSVP
FNTGARLILQHVQALLVKRFHRTVRSHKDFLAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPSNEHLTVLADVLLNKPGLGNRCLKK----------EWLP-E
YPCGN--STSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQVPEPCS----------------------------------------LWAASQ--GKG
A-----------------------------------------------------------
---------------------------------------------------------ETC
VCVCVCVCVCVCVCVSPLSFLHTH--------THTHTLSDVDL----L--SPLFKMN

PF12698 // ENSGT00760000118965_5_Domain_2 (1918, 2078)

YAV
SAGLVVGIFIGFQKKAYTSADHLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSSNPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAREPI-
-------FDEDDDVAEERQRITSGGNKSDILRLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIEKVANWGIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKSKFGDGYVVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVLRERHHSLLQFQVSSSSLARIFQLLITHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGASWPAKVEGKAGRPETKEPLPPGSAELANIYSPS-----AA
E-DKHKRRPQ------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MAMLQMEPGQ---RKKAMEATVSF
LLA---------------------------AEALLNELSSLTSLMELQQV----LQ--GE
LGASGSLEAVSRVLCEQSEKGGRGMPSLNWYEDNDLKVMLGQNDP--KPLVPPD-NRTSP
YCRKLFGELEANSITRLLWQRLKPLVIGKILYTPATPITRR-IMAEVNQTFQELALLGKL
PDVWAELGPQLFAFMNGSAEVVLLRVWLRGRGGWSLLQSPALQLLVKNDSAIHRFLAGG-
------LAQGYNWHQSLADMEQLMDSMGHFMECISLDKLEEVESEGQLVNRA-LQLLGER
RFWAGLVFLGT-QDWRPNSPGHLQIKIRMDIDDVTRTNKIKNRLWAPGPAADPFSDLRYV
SGGFIYLQDMVEGAVRRLLNGSSRHTRLYLQQMPYPCYVDDV-FLRVLNRSLPLFLTLAW
IYSVALTIKAVVREKEERLRETMRAMGLSRAVLWFSWFLSSLLPFLVSAGFLVLVLKLGD
ILPYSDSTLIFLFLATFAVATISQSFLLSTFFSRANLAAACGGLAYFTLYLPYVLCVAWR
ERLSPTLRLI----AALLSPVAFGFGCEYFSLYEEQGLGVQWHNFGASPVEGDPFNLALA
GGLLFLDAVLYGLATWYL-EAVWPGQYGIPEPWDFPFRASYWCGKWTVPESQQ-------
-----A------------------------------------------------------
----------------PAPESGDPQVLLEEPPEGLQPGVSLRGLEKRYTRSASPALRGLT
LDFYEGHITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILSGLFPPTAGSAFILGQNICSNMAAVRRLLGLCPQ
HNVLFDILTVEEHIWFYGRLKGLSAKGVQEELEPLLLDVGLSHKRHEQTRHLS--GGMQR
KLSVAIAFVGGSRVVILDEPTAGVDAFSRRGIWELLLKYRAGLA----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------

-------------------------------------MGFLRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNMNNPCF
QNPTPGESPGTVSNYNNSI-----------LARVYRDFQEFFMDTPEAQHLGQVWIELRT
LSQFMDTLRTHPERFAGRGLQIRDILKDEETLTLFLTRNIGLSDSVAHLLVNSQ-VRVEQ
FAYGVPDLELTDIACSEALLQRFIIFSQRRGAQTVRDALCPLSQVTLQWIEDTLYADVDF
FKLFRVLPTLLDS-SSQGINLRFWGGILSDLSPRMQKFIHRPSVQDLLWVTRPLLQNGGP
ETFTQLMSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPAYSYD-KRTTS
FCNSLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-LLKNANSTFEELDRVRKL
VKAWKEVGPQIWYFFEKSAQMTVIRDTLQHPTVKDFIDRQLGEEGI-PTEAILNFFSNGP
REKQADDMSSYDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLIQRA-LSLLEEN
RFWAGVVFPDM-DPWASSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGIVR

PF12698 // ENSGT00760000118965_5_Domain_0 (678, 917)

SQSRAEPPIGVYLQQMPYPCFVDDS-FMIILNRCFPVFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFFIMSMSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFATATIMQCFLLSTFFSKANLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKTT----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLS
MKMMVLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDHGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPD--------------------------------------------------
------------------HPEGMNDSFFERELPGLVPGVCVKNLVKVFEPSGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVC-SCTSKGFST-
RCPARVDEITEEQVLD--GDVKELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDAGSGS-------------------
MFIGGTQQKREQAGLRHPCSAPTEKLRRHAQAPHTCSPGQV-DPPKGQPS-PEPEDPGVP
FNTGARLILQHVQALLVKRFHHAVRSRKDFVAQIVLPATFVFLALMLSVIVPPFGDFPAL
TLHPWMYGHQYTFFSMDEPNNEQLEVLADVLLNRPGFGNRCLKE----------EWLP-E
YPCAN--ATSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPISGEALVGFLSDLGQMMNVSGGPITREASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETTDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRDPEEYGITV-ISQPLNLTKEQLSDITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPENLPALISLLMLYGWAVIPMMYPASFLFEVPSTAYVALSC
ANLFIGINSSAITFVLELFENNRMLLRFNAILRKLLIIFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--SEPAREPI-
-------FDEDDDVAEERQRVMSGGNKTDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALT
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGASWQAKLEGKSGRLETQEPLPTGSPEQLAN----ISNPTAA
E-DKHTRGPQ------------------

-------------------------------------MGFLRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNMNNPCF
QNPTPGESPGTVSNYNNSI-----------LARVYRDFQELFMDTPEVQHLGQVWAELRT
LSQFMDTLRTHPERFAGRGLQIRDILKDEEALTLFLMRNIGLSDSVAHLLVNSQ-VRVEQ
FAYGVPDLELTDIACSEALLQRFIIFSQRRGAQTVRDALCPLSQVTLQWIEDTLYADVDF
FKLFHVLPTLLDS-SSQGINLRFWGGILSDLSPRMQKFIHRPSVQDLLWVSRPLLQNGGP
ETFTQLMSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPAYSYD-KRTTS
FCNSLIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-IMKNANSTFEELDRVRKL
VKAWEEVGPQIWYFFEKSTQMTVIRDTLQHPTVKDFINRQLGEEGI-TTEAVLNFFSNGP
QEKQADDMTSFDWRDIFNITDRFLRLANQYLECLVLDKFESYDDEVQLTQRA-LSLLEEN
RFWAGVVFPGM-YPWASSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGIVKS

PF12698 // ENSGT00760000118965_5_Domain_0 (679, 917)

QMQAEPPIGVYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMALSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFATATIMQSFLLSTLFSKASLAAACSGVIYFTLYLPHVLCFAWQ
DRMTADLKTT----VSLLSSVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HPEGMNDSFFERELPGLVPGVCVKNLVKVFEPSGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETNLDVVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVC-SCTSKGFST-
RCPTRVDEITEEQVLD--GDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGS-------------------
MFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQV-DPPKGQPS-PEPEDPGVP
FNTGARLILQHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPNNEHLEVLADVLLNRPGFGNRCLKE----------EWLP-E
YPCIN--ATSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPISGEALVGFLSGLGQMMNVSGGPVTREASKEMLD

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKHLETTDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPRDRDPEEYGITV-ISQPLNLTKEQLSDITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSC
ANLFIGINSSAITFVLELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSANPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--AEPAREPV-
-------FDEDDDVAEERQRVMSGGNKTDILKLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTSISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPSKEIEKVANWGIQSLGLSLYADRLAGTYSGGNKRKLSTAIALT
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVPSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGASWQAKLEEKSGRLQTQEPLPAGS-EQLAN----GSNPTAA
E-DKHTRSPQ------------------

------------------------------------------------------------
IRFVVELVWALSLFLILIW-RNANPLYSQHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-X-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXRGIRIRDVLKDEETLTLFLVKNIGLSDSVVHLLVNAQ-VRPEQ
FAHGVPNLVLKDIACSKALLEHFLIFSQRRGAQAVLDAMCPLSQGTLQWMEDTLYANVDF
FKLFRVLPTLLDS-NSQGINLRSWGRILSDMSPRIQEFVHRPSVQDLLWVTRPLVQNGGP
QSFTQLMGILSDLVCGYPEGGGSRVFSXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXP
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-IVKNANSTFEELERFRKL
VKAWEEVGPQLWYFFDKSTQMAMIRDTLENPTVKGFINSQLGEEGI-TAEAVLNFLYKGP
RESQADDVASLDWRDVLNFTDRTLHLVNQYLECLILDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX----XSMLSPVAFGFGTEYLAREXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXGYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEETEDPE--------------------------------------------------
------------------HPEGINDSFFERELPGLVPGVCVKNLVKTFKPYGKPAVDRLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1248)

DQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLHAILQSLGMCPQ
HNILFRHLTVAEHILFYAQLKGKSWEEAQLQMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIGFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXETC-SCASKGFS-I
RCPAHIDEITPEQVLD--GDVNELMEMVRHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLPELGLSSFGISDTPLEEIFLKVTEDSDSGS-------------------
LFAGGTQQKRENISFRHQGLGPSEKAGQTPQNSNHWSAG-PIPGAEGQRSR-DP-ADGAQ
LNTGARLRLQHVQALLAKRLHHALRSRKDFLAQIVLPATFVFGALMLSVIVPPFGEYPAL
TLQPWMYGQQYTFFSMDEPGSEQLAALADVLLNRPGFGNRCMKE----------EWLP-E
YPCGNS--TSWKTPSVSPNVTHLLQKQKWTPDNPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRLQRSTDILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLPITGEAVVGFLSDLGQIMNVSGGPITREASKEMSEFL----------XW
FNNKGWHAMVSFLNVAHSAILRASLPEDKNPEEFGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVILAMSFVPASFVVYLIQERVTKAKHLQFVSGVSPTTYWLTNFLWDIMNYAV
SASLVVGIFVGFQKKAYTSPSNLPALVALLMMYGXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIYSGTSSPAVDRLCVGVRPGEX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXAANWSIQSLGLSLYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXX----------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSNVVEF
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGASRQTKV----------------------------------
----------------------------

-EKDTAAAGGALGAMYACCCLSPSHRQRARSGLVVNSMGFARQ-IKLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNVNPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYQDFQELLMGAPESQHLGQVWTELCT
LSQLMNTLRAHPERIAGRGIRIRDVLKDEETLSLFLIKSIGLSDSVVYLLVNSQ-VRPEQ
FAHGVPDLVLKDIACSEALLERFLIFPQRRAAQTVRDALCSLSQGTLQWMEDTLYANVDF
FKLFHVLPKLLDS-SSQGINLRSWGRILSDMSPRIQEFIHRPSVQDLLWVTRPLVQTGGP
ETFTQLMGTLSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAIRR-ILKNANSTFEELERFRKL
VKAWEEVGPQIWYFFDKSMQMTMIRDTLENPTVKASWNRQLGEEGI-TAEAVLNFLYRGP
REGQADDMDNFDWRDIFNITDRTLRLANQYLECLILDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQAQAEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNTVIWCTWFLDSFSIMSMSICLLTIFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKLA----VSLLSPVAFGFGTEYLARFEEQGLGLQWNNIGNSPMEGDEFSFLMS
MKMMLIDAVLYGLLAWYL-DQVFPEDYGTPLPWYFLLQESYWQGGEGCSTREERALEKTE
PVTEEMEDPE--------------------------------------------------
------------------HPAGINDCFFERELPGLVPGVCVKNLVKIFEHHGRPAVDRLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIRGKDIETSLDAIRQSLGMCPQ
HNILFHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XGMQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADILGD
RIAIIARGRLYCSGTPLFLKNCFGTGFYLTLVRKMKTIQGQGGGCKGTC-SCASKGFSI-
RCPSCVDEITPEQVLD--GDVNELMDMVCHHVPEAKLVECVGQELIFLLPNKNFKQRAYA
SLFRE-LEETLGDLGLSSFGISDTPLEEIFLKVTEDCESRP-------------------
LFAGGTQQKRENVSLRHPCLGSSSKARQTPQGSDGHPT-EPAAP----------PEGWAQ
LNTGVQLALQHVQALLVKRFHHTVRSYKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWIYGQQYTFFSMDQPDSERLMVLADVLVNKPGFGNRCLKE----------EWLP-E
FPCGN--STPWKTPSVSPDVSHLLQKQIWTADHPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------YWV--NEQRYG
GISIGGKLPAPPVTGEALVGFLSDLGQLMNVSGGPLTREASKEMSAFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLLEDRNPEEYGITV-VSQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTIYWLTNFLWDIMNYTV
SAALVVGIFIGFQKKAYTSSDNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLLRLSAVLRKLLVIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNLFQWDLIGKNLVAMAVEGLVYFLLTLLIQYQFFFSLWT--AEPAKEPI-
-------IDEDDDVAEERQRIISGGNKTDILRLNELTKIYSGSSSPAVDRLCVGVRPGEC
-D

PF00005 // ENSGT00760000118965_5_Domain_3 (2163, 2356)

LLGV-NGAGKT-TFKMLTGS-TVTSGDATVAGKSILTNISDVHRSMGYCPQFDAIDDQ
LTGREHLYLYARLRGVPAENIKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXDEPTTGMDPQARRMLWNTIMSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMAKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLGPVEQFFQ
GNFPGSVQRERHYNMLQFQISSSSLARIFRLLVSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDFPLHPRAAGASRQAKCL---------------------------------
----------------------------

-------------------------------------MGFTRQ-IQLLLWKNWTLRKRQK
IRFIVGLLWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVYRDFQEILMNAPESQHLGQVWTELRT
LSQFMDTLRTHPERIGGRGVRIRDVLKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLVLKDIACSKALLERFIIFSQRRGAQTVRDALCSLSQGTLQWMEDTLYANVDF
FKLFRVLPTLLDS-SSQGIDLRSWGRILSDMSPRIQEFVLRPSVQNLLWVTRPLMQNGGP
QTFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVFSYD-KRTTS
FCNALIQSLESNPLTKIVWRTAKPLLMGKILFTPDSQLARR-ILKNANSTFEELERVWKL
VKAWEEVGPQIWYFFDKSTQMTMIRDILENPTVKDFLNRQLSEEGI-TAEAVLNFLYKGP
PESRADNMANFDWRDIFNVTDRTLRLVNQYLECLTLDKFESYDDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMIEQGITRSQAQAEVPFGIYLQQMPYPCFVDDS-FMIILNRCFPVFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTMFIMHGR
ILHYSNPLILFLFLLVFSAATIMQCFLLSTLFSRASLAAACSGVIYFTLYLPHILCFAWQ
DQMTAELKLA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPVEGDEFSFLLS
MKMMLFDAALYGLFAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGINESFFERELPGLVPGVCVKNLVKIFEPCGKPAVDCLS
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEESQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSRTRGDKGTC-SCVSKGSSS-
RCPACVDELTPEQVLD--GDVNELMKLVHHHVPEAELVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFVGGTQQKGENVSLRHPCLGPREKARQVPQDSRSCPRED-------QCHAESE-NHSAP
LNTGARLVLQHMQALLVKRFHHATRSHKDFLAQIVLPATFVLLALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSERLAVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWRAPSVSPNVSHLLQNQKWTPDDPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLPITGEALVGFLSDLGRIMNVSGGPITREAAKEMSEFLKLLETEDNIKVW
FNNKGWHAMVSFLNVAHNAILRSSLTEDKNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPSNLPALIALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILDLFENNRTLLRFNAALRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEQHSSNPFQWDLIGKNLVAMAIEGVVYFLLTLLIQQHFFLTRWI--AEPTKEPI-
-------VDEDDDVAEERQRIISGGNKTDILRLHELTKVYSGTSSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTSVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAMALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVCSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-AHDLPLHPRAAGASGARLQAKQERNDRR--------------LEVQGLCSRGH
LNPPASVNDPTAAENKHM-RRVQ-----

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELVMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
QESQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRA-LSLLEEN
MFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSLSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLS
VQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIEISLDAVRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCSSKGFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKARQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGLQ
LNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLKKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISEVHQNMGYCPQFDAIDEM
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDNLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

-------------------------------------MSFLRQ-VRLLLWKNWTLRKRQK
LRLLVELLWPLSLFLALVWLRSINPVYRQHECHFPNKAMPSAGTLPWLQGIFCNMNNPCF
RSPTRGESPGVVSNYNNCI-----------LARVYQDAQDLLLGSH-GTELGRLWEELQT
LTHFVETIRTNPERIAGRGIRVQDILKDGENLTTFLFEDVGLSDLVVYNLMNAQ-VRPEQ
FAFGVPDLTLKDIACSKTLLNRFIIFESSGGFQAVHSAMCALSQEALQKVEDSLYANADF
FKLFQLLPTLLDS-NAQGVDLHSWGRILSDLSQAVQKLVRRPSVQDLLTTLQPHLQDGES
TSARQLMGTLSDLLCGYPEGGGSRILSLNWYEDNNYKAFL-VDGTKKESIYFYD-NTTTP
FCNTLIQTMESNTLTKIAWRAVKPLLMGKILFAPDSPAVRK-ILKNANSTFEELERLQLF
AKSWKEVGPQVWYFFQDSVQMNMIRDTLQNPTVKGFLNEQLSSEGF-TAEDVINFLSNGP
AEERNKGTVNLNWRDIFNVTNQVLHTVHQYLECLMLDKFEGQADESEVADQA-LCLLEEN
KFWAAVIFPDL-DPTASQLPPHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDLRYI
WGGFAYLQDMIEHGIIKAQTGVAVPPGIYLQQMPYPCFVDDV-FMVTLTRSFPIFMVLAW
IYSISMIVKSIVLEKEMRLKEAMKNRGVTNGVIWFTWFLDSFIMMAVSTFLLTALIMHGD
VLHYSNPHLLFLFLLTFTTASIMEAFLLSTFFSKANMAAACSGVIYFTLYLPHIVCFAWQ
DRLTVNIKIM----ASFLSPVAFGFGTEYLSRYEEQGLGLQWDNIRNSPLEGDQYSFLFS
MEMMLLDAFIYGLLAWYI-DNVFPGDYGIPLPWYFPLQPSYWLGGECTLAFITRAIEKSE
ELS---------------------------------------------------------
-----------NSFTLPASPEDSANPYFEEEPSGLIPGVCIQNLVKIFANSSRPAIDGMN
ITFYEGQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTMSILTGLFPPTSGTIWVGGQDIQTHMDSIRQNIGMCPQ
YNILFNHLTVAEHIWFYSQLKGKSREKAVFEMEMMLADIGLPHKRNEEARNLSEIGGMQR
KLSVAIAFVGEAKVIVLDEPTSGVDPYSRRSIWDLILKYRSGRTIILSTHHMDEADILGD
RIAIISQGKLHCSGTPVFLKNSFGTGFYLTLVRKMKNTETV------IL-GSKCSCSC-S
SCAPTDGAAILEQELD--GNVNEINELVHHHVPEAQLIESIGQELIYLLPSKNFKQRSYA
SLFRE-LEETLADLGLSSFGISDTPLEEVFLKVTADADPGTQNAEGTWNDYHNLRNS---
------------FLFPALSGAHKTTELRMPQGANG-----ISRRPVALKGDGSG-GKGSW
QNKGCQLFFQQMKALLIKRFHHTSRSFKDFLAQIVLPSSFVLLALILTIIIPPFGEYPGL
TLQPWIYGQQFTFFSNERPGCEETASLIDTFLNKPGFGNRCLKK----------TPLQ-N
YSCITS-STAWKTPPVPYNVSVLLQSSTWSPENPSPSCKCSTRRKLTMLPECPLGAGGLP
PPQRVQRSTEILQDLTHRNISDFLVKTYPTLIRSSLKSK----------YWV--NEQRYG
GISVGGKLPVLDVTGEQIVAFLRDLGHMMNITGGEATKVVSKEMSNFLKYMETENNIKVW
FNNKGWHAMVIFLNVANNAILRANLKQGKDPEEYGITA-INHPLNLTKEQLSEVTVLTTS
VDAVVSICVIFAMSFIPASFVLFLIQERVTKAKHLQFVSGVSSFVYWFTNFLWDILNYTV
SAGLVVAIFVVFKKKAYTSPSNLPALVTLLLLYGWAVIPMMYPASCFFSIPSTAYVALSC
INLFIGINSSAITFILELFENNPPLLKFNKTLKSILLVLPHFCLGRGLLDLAMNQAVTDV
YARFGEEHLLNPFNWDFAGKNMVALAVQGVVFFVLNLLMQRNFLSTRWL--PKNTLTPI-
-------IDEDEDVAEERQRIVNGGGKIDILNLQELTKFYTARRVPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTEVTSGDAIVAGHSVLTHISDVHQNMGYCPQFDAIDDL
LTGREHLRLYARLRGVPAAEVEKVAEWGIQKLGLLAYADQLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQSRRFLWNSIVSVIRDGRAV-----VLTSHSM-----------
EECEALCTRLAIMVKGTFKCLGTIQHLKYKYGDGYIVTMKMKAPKPGLPPDLSLAEHFIQ
VNFPGSVQREKHYNMLQYQICSYSLAKIFRLILSNKDVLNIEEYSVTQTTLDQ--VFVNF
AKQQME-DEEIPLHPRAAGANREVKVTPAFCQQATA------------------------
----------------------------

-------------------------------------MSFLRQ-VRLLLWKNWTLRKRQK
LRFLVELAWPLSLFLVLVWLRKANPVYRQHECHFPNKAMPSAGTLPWLQGIFCNMNNPCF
RNPTRGESPGIVSNYNNSI-----------LARVYQDAQELLLQAPEIHHLGRIWEELGI
MTQFMETIRTNPERITGRGLRIRDILKEEETLTSFLLNDAGLSDSVVFQLINSQQSRLLQ
FAYGVPDLTLKDIACSQTLLNRFIIFSSQRGMHAVHNAMCALSQENLQRIEDSLYTNVDF
FKLFQLLPTVLDS-KSQGVDLRSWGRVLSNVSQAVRELARKPSIQDLLLVLQPFVQGGGP
ESFGHLMSTLSDLLCGYPEGGGSRILSFNWYEDNNYKAFLGIDSTKKESIYLYD-NTTTP
FCNALIQSLESNPLTKIAWSAVKPLMMGKILFAPDSPAVRQ-ILKNANFTFEELERLRLL
TKAWEEVGPQLWHFFQNSLQMNMIRSTLKNPTVRNFLNEQLGAEGI-TAEDVINFLHNGC
PENREEGVADFDWRNIFNVTDQALRLTNQYLECLTLDKFEGHADETQLTSRA-LNLLEEN
KFWAGVVFPDI-HSGASELPPHVSYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDLRYI
WGGFAYLQDMIEHGIIKTQTNAEVPPGIYLQQMPYPCFVDDI-FMITLNRSFPIFMVLAW
IYSVSMIVKSIVLEKEMKLKEAMKNRGVSNGVIWYTWFLDSFIMMAVSVCLLTALITCGE
VLHYSNPLILYLFLLTFTTATIMQCFLLSTFFSKANLAAACSGVIYFTLYLPHIICFAWQ
DRMTINLKIM----ASLLSPVAFGFGTEYLSRYEEQGLGLQWDNIRSSPLEGDEYSFFFS
MEMMLFDALLYGLLTWYL-ESVFPGEYGIPRSWYFPLQKSYWLGSGHPNAEKTATADVEL
LLTGMSE-----------------------------------------------------
----------------VLRPKGKVTTFFEPEPPDLIPGVSIHNLVKIFAGRPKPAVDGMT
VTFYEGQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTMSILTGLFPPTSGTVLVGGKDIQMHMDSIRQSLGMCPQ
YNILFNHLTVAEHILFYAQLKGRSRKEAVLEMEMMLEDIGLPNKKNEEAQNLS--GGMQR
KLSIAIAFVGEAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIILSTHHMDEADILGD
RVAIISQGKLFCSGSPVFLKNCFGSGFYLTLVRKMKNTSQGGEC-------GSCSCSC-S
RCAPKDTVEGPEQELD--GDVNELTELIHHHVPEAKLIESIGQELVYLLPSKDFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEVFLKVTADTYPGSQNAVGGWGER---------
---GRRAGAGLA---RTTLTEQKEKAEQPPVATNGA-----SRTPAGLTRDGSE-GKGSR
QNKGSQLVYQQIKALLIKRFHHATRSHKDFLAQIVLPATFVLLALILTVIIPPFGEYPSL
ILHPWIYGHQTIFFSNERPGGEQMASLTNAFLNKPGFGNRCMKD----------EPLR-D
YPCSNT-STAWSTPSVPPNITNLFLTRKWSPDNPSPSCKCSTRKKLTMLPECPAGAGGLP
PPQRVQHSTEILQDLTYRNISDFLVKTYPTLIRESLKSK----------YWV--NEQRYG
GISIGGRLPVLHVTGNEIVDFLRHLGQMMNVTGGQASMSAAKEMSNFLKYMETEDNIKVW
FNNKGWHAMVSFLNVANNAVLRSNLWKGQAPEEYGITA-INHPLNLTKEQLSEVTVLTTS
VDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVNPAVYWLTNFLWDIVNYIV
SAGMIVGIFIGFEKKAYTSPSNLPVLIALLLLYGWAVIPMMYPASYLFSVPSTAYVALSC
LNLFIGINSSAITFILELFENNPSLQKFNNTLKNMLIIFPHFCLGRGLIDLAVNQAVVDV
YAKFGEKHILNPFQWHFVGKNLVAMAVEGVVYFALNLLMQHRLIPTRWF--SEPAKLPI-
-------SDEDEDVAEERQRIMNGENKTDILKLQELTKIYAGRHRPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTDVTSGDAVVAGNSILTHISDVHQNMGYCPQFDAVDGL
LTGREHLCLYARLRGVPAEEIERVADWGIQKLGLQMYANQLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQSRRFLWNSIVSVLRDGRAV-----VLTSHSM-----------
EECEALCTRLAIMVKGTFKCLGTIQHLKYKFGDGYIVTMKIKAPKPGLHPDPSPAEHFIQ
VNFPGSLQREKHYNMLQYQICSSSLARIFRLLISNKENLNIEEYSVSQTTLDQ--VFVNF
AKQQME-DEEIPLHPRAAGASRVVKVSPAFPRQTGE------------------------
----------------------------

------------------------------------------------------------
VRFLVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMWPWLQGIFCNVNNPCF
QNPTPGESPGIVSNYNNSI-----------LAKVYRDFQDIVMNAPESQHLGQVWTELRT
LSQLMDTLRTHPERVAGRGIRIRDILKDEETLAIFLIKNIGLSDSVVYLLLNSQ-VRPEQ
FAHGVPDLLLKDIACSRALLERFVIFHQRRGAQTVRDALCPLSPGTLQWMEDTLYANVDI
FKLFRVLPTLLDS-SSQGINLRSWGRILSDMSLRIQKXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCLTLDKFESYDDEMQLTQRA-LSLLEEN
RFWAGVVFPDM-DPWTSTLPPHVKYKIRMDIDVVEKTNKLKDRYWDSGPRADPVEDFRYV
WGGFAYLQDMIERGITRSQTRAAVPVGIYLQQMPYPCFVDDV-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHGR
ILHYSNPCIVFLFLLAFSTATITQCFLLSTFFCRASLAAACSGVLYFTLYLPHVLCFAWQ
DQMTAELKTA----MSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGSSPLEGDEFSFLLS
VKMLLFDAALYGLFAWYL-DQVFPGDYGTPLPWYFLMQESYWLGGKGCSTREERALEKTE
PLTEEMEDPEHPEGIRXXXXXXXXXXXXXXXXX---------------------------
----------------------XXXXX-X-X--X---X------------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX

PF00005 // ENSGT00760000118965_5_Domain_1 (1104, 1268)

SILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHLLFYAQLKGKSWEESQMEMEAILEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAILAQGKLYCAGTPLFLKNCFGTGFYLTLVRKMKNIQSQARGCEGAC-SCAAKGPSLG
GCPARVDELTAEQGLD--GDVNELIKVVCHHIPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLAELGLSSFGISDTPLEEIFLKVTEASNSGP-------------------
VFVGNTQQKGGTVRLQRPSLGPREKVELIPQDSIGC-STEPAPCPGDQRCPEPK-DPSAP
LNTGARLVLQHVQALLVKRFHHATRSHKDFLAQXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------XXXXXQ
YPCGNA--TPWKTPSVSPNVSLLFQKQQWTPDNPSPSCKCSTRERRTMLPECPEGAGGLP
PPQRTQRSSDVLQDLTGRDIADFLVKTYPALIRSSLKNK----------FWV--NEQRYG
GISIGGKLPGLPITGEALVGFLRGLGQIMNVSGGPNTREAAREMPDFLKQLETEDNVKVW
FNNKGWHAMVSFLNVAHNVILRSHLQEDKDSEEYGITV--ASQLNLTKEQLSEITVXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXTLLRFSAMLRKLLIIFPHFCLGRGLIDLALSQAVTEV
YARFGEEHSSNPFQWNLIGKKLLAMAVEGVVYFLLTLLTQHHFFLTQWI--RAPAKEPI-
-------VDEDDDVAEERQRILSGGSQADILRLHELTKVYSGSSGPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2324)

GEC
FGLLGV-NGAGKTTTFKMLTGDTSVTSGDATIAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAMALI
GCPPLVLLDEPTTGMDTQARRMLWNTIVSIXXXXXXX-----XXXXXXXXXXXX--XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX--X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVFVNF
AKQQTE-THALPLHPRAAGARPHAK-----------------------------------
----------------------------

-------------------------------------MGFGRQ-IQLLLWKNWTLRKRQK
IRFVVEIAWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFRELLLDAPESQHLGHVWAELRT
LSYFMGTLRTHPERIAGKGVRIRDILKDEETLTLFLIKNIGLSDSVVYLLVNSQ-VRPEQ
FAHGVPDLALKDIACSKALLERFIIFSQRHGAETVHQAMCPLSQGTLQWVEDALYANVDF
FKLFRVLPTLLDS-SSKGIDLRSWGRILSDMSPRIQEFIRRPSVQDLLWVTRPLMQKGGP
ETFTQLASILSDLLCGYPEGGGSRVFSFNWYEDNNYKVFLGIDSARKDPVYSYD-KRTTS
FCNALIHSLESNPLTKIAWRAAKPLVMGKILFTPDSPGARR-ILKNANSTFEELERARKL
LKAWEEIGPQIWYFFDKSTQMTMIRDTLGNSAVKDFLNRQLGEEGI-TAEAILNFLYTGP
RESRDDDMVNFDWRDIFNVTDRTLRLVNRYLECLVLDKFESYDDEIQLTHRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPRHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVERGITRSQGQAEVPIGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFVLFLFLLAFSTATIMQCFLLSTFFSKANLAAACSGVIYFTLYLPHILCFAWQ
DQLTAQLKMS----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGKSPVEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWFFLLQESYWLGGEGCSTREERALEKTE
PVTEEMEDPE--------------------------------------------------
------------------YPEGIHDSFFERELPGSVPGVCVKNLVKVFEPFSRPAVDRLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTSGTVLIGGKDIEMSLDEIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRRGCEGTC-SCASKEGPA-
NCPVCIDNITPEQVLD--GDVNELMEVVLHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTENSDSGP-------------------
LFAGGTQQTGRNTSLRHPCLGPREKAGQTAQ----DSP-APATQAQGQPPP-PQ-GPGIP
LNVGARLVLQHVQALLVKRFHHTVRSHKDFLAQIVLPATFVFLALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSERLAALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNITHLFQKQKWTPDDPSPSCRCSTREKLTMLPECPEGAGGFP
PPQRTQRSTEILQDLTNRNISDFLVKTYPALIKSSLKSK----------FWV--NEQRYG
GISIGGKLPGIPITGEALVGFLSDLGRIMNMSGGPITREASKEVSDFLKHLETQENIKVW
FNNKGWHAMVIFLNVAHSAILRASLPKDRDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDALVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFISGVSPITYWLTNFLWDMMNYAV
SAGLVVGIFVGFQKKAYTSPDNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFQWNLIGKNLAAMAVEGVVYFLLTLLAQHHFFLTQWV--AEPSKEPI-
-------MDEDDDVAEERQRIISGGNKTDILKLNELTKIYPGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTTVTSGDATVAGQSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLHGVPANEIERVADWSIKSLGLSLYADRLAGTYSGGTKRKLSTAMALI
GCPPLVLLDEPTTGMDPQARRMLWNIIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVRGTFRCMGTIQHLKYKFGDGYVVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASQQAKV----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLALIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFRELLVDAPESQHLGRVWTELHT
LSQVMDTLRTHPERIAGRGIRIQDVLKNDETLTLFLMKTIGLSDSVVHLLVNAQ-VRPEQ
FAHGVPDLALTDIACSRALLEHFLIFSRRRGAQAVLEAVCPLSRGALQWMEDALYANVDV
FKLFRVLSTLLDS-NSQGVNLRSWGRILSDMSPRIQEFVHRPSVQDLLWVTRPLIQNGGP
ETFPQLMSMLSDLLCGYPEGGGSQVFSFNWYEDNNYKAFLGIDSKRKDPISSYD-KVTTP
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-IMENANSTFEELERLRKL
VKAWEEVGPQIWYFFDRSTQMALIRDTLENPTVKSVMNRQLGEEGI-TAEAILNFLYKGP
QESQADGMASFNWRDVLNVTDRTLRLVNRYLECLVLNKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMIEHGITRSQVQAEVPVGVYLQQMPYPCFVDDS-FMIILNRCFPFFMVLAW
IYSVSMIVKSIVLEKELRLKETLKNQGVSNTVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILRYSNPLILFLFLLAFSTATITQCFLLSTFFSRASLAAACSGIIYFTLYLPHILCFAWQ
DRVTADLKMA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWGNIGNSPMEGDEFSFLLS
MEMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGIRDSFFERELPGLVPGVCVKNLVKIFEPHGKPAVDRLN
ITFYEDQITAILGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTSGTVLIGGKDIETNLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSREEAQLEMEAILEDTGLHHKRREAAQDLS--GGLQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAILSQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGTC-SCASKGFSV-
RCPARADEITPEQVLD--GDVNELMEMVHHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLAELGLSSFGISDTPLEEIFLKVTEDSDSGS-------------------
LFAGGTQQKRGYIGVRQPGLGPSEEARRTPPNSSGRSA-GPAAGVEAAPSPGPE-ERGAA
LNRGARLRLQHVQALLVKRSHRALRSRKDFLAQIVLPATFVFWALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSSQLATLADVLLNKPGFGNPCLKE----------EWLP-E
YPCGN--STAWKTPSVSPNVTQLFQKQKWTPGNPSPSCQCSSREKLTM-PECPEGAGGLP
PPQRLQRSTEILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLSITGEALLGFLSDLGQLMNVSGGPITKEASKEMSDFLKHLETEDNIKVW
FNNKGWHAMVSFLNVAHNAILRASLQQDKNPEEFGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVILAMSFIPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFFWDIMNYAV
SAGLVVGIFVGFQKKAYTSPSNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRALLRLNATLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHAANPFQWDLIGKNLVAMAAEGVVYFLLTLLIQHHFFFTRWI--AKPAKEPI-
-------IDEDDDVAEERQRIISGGNKADILRLNELTKIYSGTTGPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFRMLTGDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVADWSIQSLGLCLYADCLAGTYSGGNRRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTITGIIKEGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKSAKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVTF
AKQQTE-THNLAFHPRAAGAQTKKISCKQENDQ------------FSQ---VQALCPQGH
LNDPVSTNPTAA-ENQ----CVRRVN--

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELIWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPELALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQRTLQWIEDTLYANVDF
FKLFRVLPTLLDS-HSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQAILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVTIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEATLVECIGQELIFLLPSKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENINPQHPCLGPRGKAGQTPQDSNVFSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFVGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIRSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

------------SGISVLCCCRG-PGPGRPGPHLRADVGILRH-LPLLLWKNWTRRKRRK
IRFVVELVWPLSLFIVLIWLRNANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNVNNPCF
QSPTQGESPGIVSNYNNSI-----------LARVYQDVQELLINAPESKLLGQMWSELRM
LSQLMETLRTHPERIAGRGIRIKDILRDEETLTHFLVHTFGLPDSVVYLLMNSQ-VRPEQ
FAYGVPDLMLKDIACSEALLNRFIIFSQRRGAQTVQRAMCPLSQGSLQWVEDALYSNVDF
FKLFQLXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXLAHRPSVQDLLWVTGPLLQNGGP
ESFSQLMRILSELLCGYPEGGGSRVFSYNWYEDNNYKAFLGIDPSRKDPVYSYD-KTTTS
FCNSLIQNMEANPLTKIAWSAAKPLLMGKILFTPDSPAVHR-ILKHANSTFEELERVRNF
LKAWEEVGPQIWHFFDNSTQITMIRXXXXXXXXXXXXXXXXXXXXX-XXXAVLNFLYNGP
EEGRPKDMVRFDWRNVFNFTDHTLRLVNQYMECLTLDKFESYDDEIQLTHRA-LSLLEQN
RFWAGVVFSDI-YPWNSVPPRHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVEDFRYI
WGGFAYLQDMIEQGIIRSQTKAEVPIGVYLQQMPYPCFVDDV-FMITLNRCFPVFMVLAW
IYSVSMVVKSIVLEKEMRLKETLKNRGVSNAVIWCTWFLDSFSVMAMSTFLLTAFIMHGQ
VLHYSNPVILFLFLLVFSIATIMQCFLFSAFFSKANLAAACSGVLYFTLYXXXXXXXXXX
XXXXXXXXXX----XSLLSPVAFGFGTEYLSRYEEQGLGLQWGNIGTSPMEGDEFSFFLS
IKMMLIDAAFYGFLAYL--DQVLPGDYGTPLPWYFLLQESYWLGGEXXXXXXXXXXXXXX
XXX---------------------------------------------------------
-----------XXXXXXXXXXXXXXTFFEREQPGLVPGVCVQNLVKVFDYQGKPAVDRLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1248)

NQITAFLGHNGAGKTTTMSILTGLLPATSGTVLIGGKDIETNMDSIRQDLGMCPQ
YNILFHHLTVAEHILLYAQLKGKSRKEAQLEMETMLEDTGLHHKRNEEAQNLS--GGMQR
KLSVAIAFVGDAKVIVLDEPTSGVDPYSRRSIWDLLLKYRSXXXXXXXXXXXXXXXXXXX
XXXXXXXXXLYCSGTPLF-KNCFGTGFYLTLVRKMKNIQSHGKGCEXXX-XXXXXXXX-X
XXXXXXXXXXXXXXXX--XDINELIEVIHHHVPEAKLVECIGQELIFLLPNKDFKQRAYA
SLFRE-LEETLSDLGLSSFGISDTPLEEXXXXXXXXXXXXXXXX----------------
---XDTQQKGPSFSFRNPSSSRNEKATGGPQASNGSSAPEPPHSAEGPASKESE-EHGMQ
LNKGTQLLCQHVQALLIKRFHHAVRSRKDFLAQIVLPAGFVCLALLLAAIIPPFGEYPPL
MLHPWIYGHQYTFFXXXXXXXXXXXXXXXXLLNRPGFGNRCLKE----------ELFP-N
YPCGNS--TSWKTPSVSPNVTHLFQKQKWTADNPSPSCKCSTQEKLTMLPECPEGAGGLP
PPQRVQRSTEILQDLTNRNISDFLVKTYPTIIRSSMKSK----------YWV--NEKRYG
GISIGGKLPVFCITGEEIVGFFRDLGQLMNVSGXXXXXXXXXXXXXXLKYLETEDNIKVW
FNNKGWHAMVAFLNVANNAILRANLPKDVDPEDFGITL-INQPLNLTKEQLSEITVLTTS
IDAMVAICVIFAMSFIPASFVLYLIQERVSKAKHLQFVSGVSPTTYWVTNFLWDIXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWAVIPMMYPASFLFDVPSTAYVVLSC
TNLFIGXXXXXXXXXXXXXXXXXTLLRFSAMLRKALLIFPHFCLGRGLIDLALNQAVTDV
YAAFGEEHFSDPFQWNMIGKNLVAMAIEGGVYFILNLLLQHHFFLTRXX--XXXXXXXX-
-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

XXC
FGLLGV-NGAGKTTTFKMLTGDITVTSGDATVMGKSILTQISEVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGXXXXXXXXVADWCIQSLGLSPYADHMVGSYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQSRRLLWNTIVGIIRGGRAV-----VLTSHSM-----------
EECEALCTRLAIMVRGTFQCLGTIQHLKYKFGDGYIVTMKIKPPKVGLLPDLNPAEQFLQ
ANFPDSIQRERHYNMLQYRISSSSLARIFQLLISNKDSLYIEEYSVTQTTLDQ--VFVNF
AKQQTE-EDDLLLHPRAAGAIPDVK-----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQYLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEEGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQAILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAMAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEATLVECIGQELIFLLPSKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENINPQHPCLGPRGKAGQTPQDSNVFSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVIPVTGEALVGFLSDLGQIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVTLSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSTNPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLQELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

-------------------------------------MGFLRQ-IRLLLWKNWTLRKRQK
IRFIVELVWPLSLFVVLIWLRSANPLYSQHECHFPNKAMPSAGLLPWLQGIFCNVNNPCF
QSPTQGESPGIVSNYNNSI-----------LARVYRDVQELLINAPESQLLGQIWNELRK
LSQLMEILRNNPERIAGKGIRIKDILKEEETLTHFLVHTFGLPDSVVYLLMTSQ-VRPEQ
FAYGVPDLMLKDIACSETLLNRFIIFSQRGGARTVQRAMCPLSQGSLQWVEDALYSNVDF
FKLFQLLPTLIDG-SSQGVNLRSWGSALSNMSPKVQEFVHQPSVQHLLWVTGPLLQNGGP
ESFSQLMSILSELLCGYPERGGSRVFSYNWYEDNNYKAFLGIDPSRKDPVYSYD-KRTTS
FCNSLIQNMEANPLTKIAWRAAKPLLMGKILFSPDSPAVHR-ILKHANSTFEELDRVRKF
LKAWEEVGPQIWHFFDNSTQMTMIRDTLENPTVKSFVNRQLDEEGL-TAETILNFLYNGP
QEGRPKGMVNFGWRNVFNFTDGILRLLNQYMECLTLDKFEIYDDEIQLTHRA-LSLLEQN
RFWAGVVFFDM-YSWNSELPHHVKYKIRMDIDAVEKTNKIKDRYWDPGPRADPVEDLRYI
WGGFAYLQDMIEQGIIRSQTKAEVPTGVYLQQMPYPCFVDDV-FMITLNRCFPVFMVLAW
IYSVSMTVKSIVLEKEMRLKETLKNRGVSNMVIWCTWFLDSISVMAMSTFLLTAFITHGQ
VLHYSNPVILFLFLLVFSMATIMQCFLFSAFFSKANLAAACSGVLYFTLYLPHILCFAWQ
ERMTAEQKTW----VSLLSPVAFGFGTEYLSRYEEQGLGLQWGNIGKSPMEGDEFSFLLS
IKMMLIDAVLYGFLAWYL-DLVFPGDYGTPLPWFFLLQESYWLGNEACSTKEERALEKTE
PLTEEMQNPD--------------------------------------------------
---------------YSGE---IQDTFFEKEQPGLVPGVCVQNLVKVFNYQSRPAVDHLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTMSILTGLLPATSGTVLIGGKDIETSMDSIRQNLGMCPQ
HNILFHHLTVAEHILLYAQLKGKSRKEAQLEMETMLEDTGLHHKRNEEVQNLS--GGMQR
KLSVAIAFVGDAKVIVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISRGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQGKGCEEAC-SCTPKGTS-I
SCPAKVEEITAEQVLD--GDVNELIGMIHHHVPEAKLVECIGQELIFLLPNKDFKQRAYA
SLFRE-LEETLPDLGLSSFGISDTPLEEIFLRVTGDSESGA-------------------
LFVGDTQQKGPSFHFRNPSSGSNE-KTRGAQTSNGAPAPEPTHPAEGQASKEPE-DTGMH
LNKGPQLICQHVQALLIKRFHHTVRSHKDFLAQIVLPAGFVCLALVLAVIIPPFGEYPAL
TLHPWIYGQQYTFFSSEQPGNENLSTLMEVLLNNPGFGNRCLKD----------ESLL-N
YPCGNS--TSWKTPSASPNMTQLFQKQKWTPDNPSPSCKCSTQEKLMMLPECPEGAGGPP
PPERVQRSMEILQDLTNRNISDFLVKTYPGLLRSSMKSK----------YWV--NEQRYG
GISIGGKLPVFCITGKQIVDFLQDLGQLMNVSGGPATLEASKEMSNFLKYLETEDNIKVW
FNNKGWHAMVTFLNVANNAILRAKLPKAMDPEDFGITL-INQPLNLTKEQLSEITVLTTS
IDAMVAICVIFAMSFIPASFVLYLIQERVSKAKHLQFVSGVSPTTYWVTNFLWDIVNYSV
SAGLVVGIFIGFQKRAYTSPQNLPALIALLFLYGWAVIPMMYPASFLFDVPSTAYVALAC
ANLFIGINSSAITFVLELFENNRTLLKFSAMLRKALLIFPHFCLGRGLIDLAVNQAVTDV
YAAFGEEHSSDPFQWDLIGKNLVAMAVEGGVYFAMNLLIQHHFFLTRWI--AEPPKQPI-
-------SDEDDDVAEERQRILSGSNKTDILRLHELTKIYSGTTSPAVDRLCIGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDISVTSGDAIVAGNSILTQISEVHQHMGYCPQFDAIDDL
LTGREHLYLYARLRGVPTEDIKRVANWCIQSLGLSVYADHLVGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQSRRLLWNAIVGIIRDGRAV-----VLTSHSM-----------
EECEALCTRLAIMVRGTFQCLGTIQHLKYKFGDGYIVTMKIKPPKVGLLPDLNPAEQFLQ
ANFPGSVQRERHYNMLQYRISSSSLARIFQLLISNKDSLYIEEYSVTQTTLDQ--VFVNF
AKQQTE-EDDLPLHPRAAGAIIDAKVAPAPPSRDGVESKPSAQTRCTA--------QVG-
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLILIWLRNINPLYSQHECHFPNKAMPSAGMLPWLQGMFCNVNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVFRDFQELLLDAPERQHFGHVWKEFQT
LSRLMDTLRTHPERVAGRGIRIRDVLKDEETLTLFLMKNIGLSDSVVYLLLNSQ-VRPEQ
FAHGVPDLMLKDIACSETLLERFIIFSQRRGAQTVRDAMCSLSQGTLQWVEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRSWGRVFSDISSRIREFIHRPSVEDLLWVTKPLTQTGGP
ETFAQLMSILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTT
FCNALIQSLESNPLTKIAWRAAKPLVMGKILFTPDSPAVRR-ILQNANSTFEELERLRKL
VKAWEEVGPQIWYFFDRSTQMTMIRDTLENPTVKGFLNSQLGEEGI-TAEAMLNFLHKGP
RESQADDMANFDWRDVFNITDRTLRLTSKYLECLILDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSALPTHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYL

PF12698 // ENSGT00760000118965_5_Domain_0 (668, 917)

QDMIEQGITRSQAQVEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKMA----VSLLSPVAFGFGTEYLARFEEQGLGLQWSNIGKSPMEGDEFSFLMS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGNYGTALPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGINDAFFERELPGLVPGVCVKNLVKIFEPYSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
YNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGGAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1793)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRTGCEGTC-SCASEGFST-
RCPAHIDEITPEQVLD--GDVNELMDMVQHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEDTLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGTQQKREN--LRHPWLSPREKARQIPQGSNGCSA-EPAPHPEGQPSSEP--EARSR
LNTGAQLIIQHVQALLVKRFHHTIRSHKDFLAQIVLPATFVFLALMLSIIVPPFGEYPAL
ILHPWMYGQQYTFFSLDQPGSEQLAALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNITHLFQKQQWTPEKPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWWILNHERYG
GISIGGKLPILPITGEALVEFLSHLGQIMNVSGGPITREASKEMPAFLKHLE

PF12698 // ENSGT00760000118965_5_Domain_2 (1793, 2078)

TEDNIKVW
FNNKGWHALVSFLNVAHNAILRTSLHKDKNPEEYGITV-ISQPLNLTKEQLSEITVLTAS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYAV
SAALVVGIFVGFQKKAYTSPENLPALIALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNWTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSTNPFQWDLIGKNLVAMAAEGVVYLLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

FIQHHFFLTRWV--SEPAKEPI-
-------IDEDDDVAEERQRIISGGNKTDILRLNELTKIYSGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQSMGYCPQFDAVDDL
LTGREHLYLYARLRGVPADEIERVANWSIQSLGLSLYADRLVGTYSGGNKRKLSTAIALM
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKEDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFRLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGASRQA---------------------KLRDWSVGPEGPQG-
----------------------------

-------------------------------------MGFPRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHQCHFPNKAMPSAGMLPWLQGIFCNMNNPCF
QNPTPGETPGIVSNYNNSI-----------LARVYRDFQELFMDTPEIQHLGQVWAELRT
LSQLMDTLRTHPKRFAGRGLQIRDILKDEETFTLFLTRHIGLSDSVAHLLVNSQ-VRVEQ
FAYGVPDLELKNIACSEVLLQRFIIFSQHWGAQTVRDTLCPLSQVTLQWIEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRFWGGILSDMSPRIQKFIHRPSVQDLLWVARPVLQNSGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPTYSYD-KRTTS
FCNALIQNLESNPLTKIAWRAAKPLLMGKILFTPDSPAVQR-LLKNANSTFEELDRVRKL
VKAWGEVGPQIWYFFEKSTQMTMIRDTLGHPTVKDFINRQLGEEGI-TTEAILNFFPNGP
RENQADDMTNFDWRDIFNITDHFLHLANQYLECLVLDKFESYGDEVQLIQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGIIRSQTQAEVPIGVYLQQMPYPCFVDDS-FMIVLNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTLFIMHGR
ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTANLKMI----VSLLSPVAFGFGTEYLVRFEEQGLGLQWDNIGKSPMEGDEFSFLLS
MKMLLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALERTE
PLTEEMEDPE--------------------------------------------------
------------------HPEGMSDSFFERELPGLVPGVCVKNLVKVFEPCSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIAGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1792)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKSIQSQRSGCEGAC-SCTSKGFST-
RCPARVDEITEEQVLD--GNVKELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSSS-------------------
MFAGGMQQKREHGGLRHPCSVPTEKVRQPAQGPHTCFPGQV-DPSKGQPS-SEPEEPGAP
FNTGARLILQHVQALLVKRFHHSVRSHKDFLAQMVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPSNEHLEVLADVLLNKPGFGNRCLKK----------EWLP-E
YPCGN--STSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPITAEALVGFLGDLGQMMNVSGGPVTREASKEMLEFLKHL

PF12698 // ENSGT00760000118965_5_Domain_2 (1792, 2078)

ETKDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKHRDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVIAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIINYAV
SAGLVVGIFIGFQKKAYTSADNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSSNPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAREPI-
-------FDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIEKVANWGIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVSSSSLARIFQLLVTHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQME-TYDLPLHPRAAGASWQGKLEGKAGRPETKEPLPPGSTEQLAN----INNPSEA
E-DKHTRRPQ------------------

-------------------------------------MNFFRQ-VRLLLWKNWILRKRQK
LRFLVELLWPLSLFFVLVWLRKANPLYRQHECHFPNKAMPSAGTLPWLHGIFCNMNNPCF
RSPTHGEGPGVVSNYKNSI-----------LARVYKDAQELLLETPEIHDLGRIWEELII
MTQFMETMRTNPERIAGRGIRILDILKDGETLTSFLLENVGLTDFVVYQLINAQ-VRPEQ
FAYGVPSLTLKDIACSEALLDRFIIFSSRRGLPSVHKAMCALSQDSLQRVEDALYANVDF
FKLFQMLPTVLDR-NSPGADLKAWGRVLSNVSQAVQKLARKPSVQDLLRVLQPLVEDGRP
ESLGHLVSSLSDLFCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKKSGYLYD-NTTTP
FCNALIQNLESNPLTKIAWSVVKPLLMGKILFAPDSPSVRE-IVKNANSTFEELERLQLL
TKAWEEVGPQLWYFFQNSLQMNMIRDSLKHPTVRHFLNSQMGAEGF-TAEHIINFLHNGS
SRSREKGMVDFDWRNIFSAVDQVLRLLSQYLECLTLDKFEGYLDETQLTRQA-LYLLEEN
KLWAAVVFSDL-EPIASNLPPHVTYKIRMDIDAVEKTNKIKDRYWDPGPRADPVDDLRYI
WGGFAYLQDMIEHGIIKTQTSTEVPLGIYLQQMPYPCFVDDV-FMITLNRAFPIFMVLAW
IYSVSMTVKSIVLEKEMRLREAMKNRGITNGVIWCTWFLDSFSMMAVSTLLLTALIMHGQ
VLHYSNPFLFFLFLLTFTTATIMQCFLFSTFFSKANLAAACSGVIYFALYLPHIVCFVWQ
DRLTVNLKIL----ASLLSQVAFGFGKASHITFSEYFTAVQKKNKKKSVNKICSVTYLMN
LCL-L----WNGVMKCTLPTYFCFGDYGLPQPWYFPVLESYWLGSRSPEAEKTATADVTS
PQTTT-------------------------------------------------------
---------------------VLVNTFFEPEPTGLIPGVCIQNLVKIFANRPKPAVDGIN
ITFYEGQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTMSILTGLFPPTSGTVLVGGLDIQTHMDSIRHRLGMCPQ
HNILFNHLTVAEHILFYSQLKGRSREEAEQELETMLEDMGLTNKRNEEAQNLS--GGMQR
KLSVAIAFVGEAKVVVLDEPTSGVDPYSRRSIWDLLLKYRPGRTIILSTHHMDEADILGD
RVAIISQGKLFCSGSPVFLKNCFGSGFYLTLVRKMRTTKMGRATV-----SMNCSCSC-S
SCVHGGEEGAPEMELD--GDLNELAEVIHHHIPEAKLIESIGQELIYLLPSKNFKQRSYA
SLFRE-LEETLDDLGLSSFGVSDTPLEEVFLKVTAEANSEMQKT----------------
---GDTQGNGSA---LGKTPTENKPAEQTALKTNDA-----SQTPVGRPGDQNE-GRGSR
QYKGFQLVHQQIKALLIKRFHHASRSHKDFLAQVVLPASFVLLSLVLTVIIPPFGEYPAL
TLHPWMYGQQFTFFSNEQPGNEQMVSLTHAFLNKPGFGIRCMKN----------QPLL-N
YPCNNM-PTAWSTPAVHPNLSSLLLSQEWSPENPSPSCKCSTQKKLTMLPECPAGAGGLP
PPQRVQRSTEILQDMTHRNISDFLVKTYPTLIKGSLKSK----------YWV--NEQRYG
GISIGGKLPVLHVSGDQIVNFLSDLGRMMNVTGGQTSLAAAKEIPNFLKYMETEDNIKVW
FNNKGWHAMVSFLNVANNAILRANLRTGQDPEEYGITA-INHPLNLTKEQLSEVTVLTTS
VDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPVTYWLTNFMWDIMNYAL
SAGMVVAIFAGFNKKAYASPANLPVLVALLLLYGWAVIPMMYPASSFFSIPSTAYVALSC
INLFVGINSSAITFILELFENNPSLLKFNKTLKNVLLVLPHFCLGRGLIDLAMNQAVTEL
YARFGEERVSDPFQWDFVGKNLVAMALQGVVFFFLNLFMQHRLFSTRWF--AETAMSPI-
-------INEDEDVAEERKRIMNGGNKTDILQLQELTKIYAGQSKPAVDRLCVGIRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTDVTSGDAVVAGSSILTHISNVHQNMGYCPQFDAIDDL
LTGREHLHLYARLRGVPAEEIKRVAEWGIQKLGLALYADHLAGTYSGGNKRKLSTAIALI
GCPPLILLDEPTTGMDPQSRRLLWDSIVDVLRGGRAV-----VLTSHSM-----------
EECEALCTRLAIMVQGTFKCLGTIQELKYKFGDGYIVTLKIKAPKSGMPPDPAPAEKFIR
TNFPGSLQREKHYNMLQYQICSSSLAKIFRLIISNKENLHIEEYSVSQTTLDQ--VFVNF
AKQQLE-DEEIPLHPRAAGASREARV----------------------------------
----------------------------

-------------------------------------RKFFRS-IATGL---SLCVLFLQ
IRFVVELVWPLSLFLVLIWLRNANPLYSHHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHFGQIWIELRT
LSQLMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSSSVVHLLVNSQ-VRVEQ
FAHGVPDLVLKDIACNEVLLERFIIFGQRHGAWAVRDALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-NSQGINLRSWGKIVSDLSPRIQGFIHQPSVQDQLWVTRPLLQNGGP
QTFTQLMSIPSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPLYSYD-KGTTA
FCNALIQSLESNPLTKIAWRAAKPLLMGKIIFTPDSPAAQR-ILKNANSTFEELARLRKL
VKAWEEVGPQIWYFFESSTQMTMIRDTLEHPTVKDFLNRHVGEEGI-TAEILLNFLYKGP
PENRADGMTNFDWRDIFNITDRSLRLVNQHLECLVLDKFESYDDEIQITQRA-LSLLEEN
RFWAAVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQAQVEVPVGVYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLMIFIMVS-
--------------------QMEKCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKAVVRAWGS----------PC-------------------------------
-----------------------------------LPSSHVCLPLLGCSTREERALEKTE
PITEEMEDPD--------------------------------------------------
------------------HPGGKNDSFFERELPGLVPGVCVKNLVKIFEPGTRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1199)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPATSGTVLIAGKDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLGMEAMLEDTGLHHKRNEEAQDLS--GAW

ENSGT00760000118965_5_Linker_1_2 (1199, 1917)

CW
KVTGPRM----AHPLLLSAPRR---------------------VITES------------
PNAPFSNGR-------------WKKMEYLTIS--------------------QSSGFWR-
-------IELNSIFFHVLGDVNELMDVVCHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFADGTQTKREHASMRHPCLVPSEKAQQAAQSSSTCSPVQPP---------LEPQDRGTV
LNTGLRLVLQHVQALLIKRFHHATRSRKDFLAQMVLPATFVFLALVLSIIVPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSKHLQVLADVLLNKPGFGNRCLKE----------EWLL-E
YPCGN--STPWKTPSVSPNITHLFQKQKWTPANPSPSCQCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQNLTNRNISDYLVKTYPDLIR-----------------------NRYG
GISIGGKLPVLLITGEDLVGFLSELGQMMNVSGGPVTREASKEMSDFLKYLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLHKDRNPEEHGITV-ISQPLNLTKEQLSEITMKSTP
DPKIWRILV-------PSLIVQ--------TMKQVLVVHDL------LS--SLFKI

PF12698 // ENSGT00760000118965_5_Domain_2 (1917, 2077)

NYAV
SAGLVVGIFVGFQKKAYTSPSNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFESNRTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSPNPFQWDLIGKNLIAMAAEGVVYFLLN

ENSGT00760000118965_5_Linker_2_3 (2077, 2150)

LLVQKHFFFTRWI--AEPPREPI-
-------VDEDDDVAEERQRITSGGDKTDILRLNQLTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGIRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISEVHQNMGYCPQFDAVDDL
LTGREHLYLYARLRGVPAKEIEKVANWSIQSLGLSLYADRLVGTYSGGNKRKLSTAMALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSILREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLFIEEYSVTQTTLDQ--VFVNF
ANKQQTEPHDLPLHPRAAGASQKAKVLLLPFLSPLLEADP----GLP--------GPVGP
LHLR------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQTDDMANFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 827)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIY

ENSGT00760000118965_5_Linker_0_1 (827, 1077)

FTLYLPHILCFAWQ
DRMTAELKKA----VVR--PLGWPM--SYN----------------TFPRKG--------
-----------------K-HPPLYGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSREEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKDSEGTC-SCSSKGFST-
TCPAHVNDLTPEQVLD--GDVNELMDVVLHHIPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEEMLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHLCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISVGGKLPVIPITGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAVLRASLPKDRSPEEYGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPITYWVTNFLWDIMNYAV
SAGLVVGIFVGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSS-------------TLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVAEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AQPPKEPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYSGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTAYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQVPLLLML-----------------SAA--------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLILIWLRNANPLYSQHQCHFPNKAMPSAGMLPWLQGIFCNVNNPCF
RSPTPGESPGIVSNYNNSI-----------LARVYRDFQEVLVDAPESQHLGQVWVELRT
FARFMDTLRTHPERFAGRGIQTRDILKDEETLTLFLVRNIGLSNSVANLLVNSQ-VRVEQ
FAHGVPDLALKDIACSKALLERFIIFSQYRGAQTVRDTLCPLSPGTLQWMEDTLYANVDF
FKLFRVLPTILDR-SSQGINLRSWGRILSDISPRIQEFIHRPSVQDLLWVMRPLLQKSGP
ETGTQLMSLLPDLVCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAVRR-ILKNANSTFEELERLRKL
IKAWGEVGPQIWYFFDKSTQITMIRDTLGHPTVKDFVNKQLTGEGV-TAEAILNFLYKGP
GDNPSEDTTDFDWRDIFNITDRSLRLINQYLECLVLDKFESYDDEMQLTQRA-LSLLEQN
RFWAGVVFLDM-YPWTSHLPRHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDLRYI
WGGFAY

PF12698 // ENSGT00760000118965_5_Domain_0 (667, 917)

LQDMVEQGITRSQARAAAPIGVYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMLMSIFLLTIFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSKASLAASCSGVIYFTLYLPHILCFAWQ
DRMTAELKQA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWDNIGNSPMEGDEFSFLLS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HP-GMNDSFFERELPGLVPGVCVKNLTKVFESCSRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYESQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDEIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLETEGMLEDTGLHHKRNEGAQDLS--GGMQR
KLSVAIAFVGDSKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1787)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGTC-SCASKGFS--
RCPARVDEITEEQVLD--GDVNELKDLVRHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDAGS-------------------
LFAGGTQQKREPTTLRHPYLGSNKK---GGQPPHTCSPGQA-APSEGQTSPPEPEDSSLP
LNTGTRLIFQHVQALLVKRFHHTLRSYKDFLAQIVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGKQYTFFSMDEPGSERLAELADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTLSVSPNLTHLFQKQKWTTANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQPSTEILQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPITGEALVSFLRDLGQIMNVSGGPITREASKEIPE

PF12698 // ENSGT00760000118965_5_Domain_2 (1787, 2078)

FLKYLETQDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKGRNPEEHGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFVSGVSPTTYWLTNFLWDIMNYAV
SAGLVVGIFIGFQKKAYTSPQNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFVGINSSAITFILELFENNRTLLRFNTMLRKLLIIFPHFCLGRGLIDLALSQAVTEV
YARFGEEHISNPFQWNLIGKNLVAMAVEGVAYLLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWI--AKPTREPI-
-------TDEDDDVAEERQRIISGGNTSDILRLNELTKVYSGSTSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGIHPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTDISDVHQRMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRLLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQYQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-TYDLPLHPRAAGASQQAKVHPPSSQPAH---WACGAPGFCRE-----------
-LHMEPP---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSSS-------------------
MFAGGMQQKREHGGLRHPCSVPTEKVRQPAQGPHTCFPGQV-DPSKGQPS-PEPEEPGAP
FNTGARLILQHVQALLVKRFHRAVRSHKDFLAQMVLPATFVFLALMLSIIVPPFGEFPAL
TLHPWMYGHQYTFFSMDEPSNEHLEVLADVLLNKPGFGNRCLKK----------EWLP-E
YPCGN--STSWKTPSVSPNITHLFQKQKWTAAHPSPSCKCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAIPITAEALVGFLGDLGQMMNVSGGPVTREASKEMLEFLKHLETKDNIKVW
FNNKGWHALVPTSAMKVQGLK-----------VYITTP-VLFPL--FKNE---IKAYTG-
------------------------NGERAQRLKVLAALAGVL-----SSVLSNHI

PF12698 // ENSGT00760000118965_5_Domain_2 (1916, 2078)

INYAV
SAGLVVGIFIGFQKKAYTSADNLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAMLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YAQFGEEYSSNPFQWDLIGKNLVAMAIEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHHFFLTRWV--AEPAREPI-
-------FDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGSSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIEKVANWGIQSLGLSLYADRLVGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHHSMLQFQVSSSSLARIFQLLVTHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQME-TYDLPLHPRAAGASWQGK-----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFAVELVWPLSLFLILIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLSLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLEHFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFHVLPTLLDS-RSQGINLRSWGGILSDMSPRIQQFIRRPSVQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDTTRKDPIYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYAPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TVEAILNFLYKGP
RESQADDLANFDWRDIFNVTDRTLRLVNQYLECLVLDKFENYDDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHMKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKENLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWNNIGNSPTEGDEFSFLLS
MQMMLLDAAIYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEEMEDPE--------------------------------------------------
------------------HPGGIHDSFFEREHPGWVPGVCVKNLVKTFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGRDIETSLNAIRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1789)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRRGSEGTC-SCASKGFSTT
TCSAHVSDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPSKNFKQRAYA
SLFRE-LEETLADLGLSSFGVSDTPLEEIFLKVTEDSGSGP-------------------
LFAGGTQQKRENVNRRHPCLGPRENTGQIPQDSNDCSPGALAAHPEGQPPPEPE-CPGPQ
LNTGTRLVLQHVQALLLKRLQHTVRSHKDFLAQIVLPATFVFLALLLSIIIPPFGEYPAL
TLHPWMYGHQYTFFSMDEPGSEQLTVLADVLLSKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNVTQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPVTREASKEIPAFL

PF12698 // ENSGT00760000118965_5_Domain_2 (1789, 2078)

KHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYTV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRMLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YTRFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2151)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRVITGGNKTDILRLHELTKIYPGTSSPAVDR

PF00005 // ENSGT00760000118965_5_Domain_3 (2151, 2292)

LCIGVRAGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYFYARLRGVPAEEIEKVADWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSLRDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

-------------------------------------MGFARQ-IKLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNVNPLYSKHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTAGESPGIVSNYNNSI-----------LARVYRDFQELLMDAPESQHLGQVWKELCT
LSQLMNTLRMHPERIAGRGIRIRDVLKDEETLTLFLVKNIGLSDSIVYLLVNSQ-VRPEQ
FARGVPDLMLKDIACSEALLERFLIFPQRRAAQTVRGSLCPLSQGTLQWMEDTLYANVDF
FKLFHVFPRLLDS-SSQGMNLRSWGRILSDMSPRIQEFIHRPSVQDLLWVTRPLVQTGGP
ETFTQLMGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-ERTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPATRR-ILKNANSTFEELERVRKL
VKVWEEVGPQIWYFFDKSTQMTMIRDTLENPTVKAFWNRQLGEEGI-TAEAILSFLYKGP
REGQADDVGNFNWRDIFNITDHALRLANQYLECLILDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDM-HPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMVEQGITRSQAREEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNRVIWCTWFLDSFSIMSMSICLLTIFIMHGR
ILHYSNPFVLFLFLLAFSIATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRITADMKMA----VSLLSPVAFGFGTEYLARFEEQGVGLQWSNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERAWEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGINGCFFERELPGLVPGVCVKNLVKIFEPYGRPAVDRLN
ITFYESQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSIMTGLLPPTSGTVLVGGKDIETNLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWDEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGVQR
KLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADILGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKTIQSQGRGCEGTC-SCASKGFSV-
RCPACAEPMTPEQVLD--GDVNELTDMVRHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDLDSGH-------------------
LFAGGPQQKRENINLRHSCLGPSEKARQTPQGSSSHPG-EPAAHPEGQPPP--EQEGHSR
LNSGARLVVQHVHALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSLIIPPFGEYPAL
TLHPWMYGQQYTFFSMDQPDSEWLSALADVLVNKPGFGNRCLKE----------EWLP-E
FPCG--NSSPWKTPSVSPDVTHLLQQQRWTADQPSPACRCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQDLTDRNVSDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPAPPITGEALVGFLSDLGQLMNVSGGPMTREAAKEMPAFLKQLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLHKDKNPEEYGITI-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYTV
TAALVVGIFIGFQKKAYTSSDNLPALVALLMLYGWAIIPMMYPASFLFDIPSTAYVALSC
ANLFIGINSSAITFVLELFENNRTLLRINAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWDLIGKNLAAMAIEGVVYFLLTLLIQYQFFFSRWT--TEPAKEPI-
-------IDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTPVTSGDATVAGKSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVTNWSIQSLGLSLYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIMGIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIRPPKDDLLPDLGPVERFFQ
GNFPGSVQRERHRNMLQFQVSSSSLARVFRLLVSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-TYDLPLHPRAAGASRQAKEVDKGNSAPQG------------------------
----------------------------

EKDSAAWARGDLGGICV-HCYPN-LSHTQSGLHVVNSMGFARQ-IKLLLWKNWTLRKRQK
IRFTVELLWPLSLFLVLIWLRNVNPLYSQHECHFPNKAMPSAGTLPWLQGIFCNVNNPCF
QHPTPGETPGIVSNYNNSI-----------LAKVYQDFQEIIMNAPESQHLGQVWTELRT
LSQLMDTLRTHPERIAXXXXXXXXXXXXXETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLVLKDIACSTALLERFIIFSQRRGAQTVRDALCSLSQGTLQWMEDTLYANVDF
FKLFRVXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXFVLRPSVQNLLWVTSPLMQNGGP
ETFTQLMGIMSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVYSYD-KRTXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXDILENPTVKGFLNGQLSEEGI-TAEAVLNFLYNGP
RESRAGNMANFDWRDIFNVTDHTLRLVNQYLECLTLDKFESYDDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYV
WGGFAYLQDMIEQGITQSQAQAEVPIGIYLQQMPYPCFVDDS-FMIILNRCFPVFMVLAW
IYSVSMTVKSVVLEKELRLRETLKNQGVSNTVIWCTWFLDSFSVMSVSIFLLTVFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFGSA----AACSVIYFTFYLPHVLCFAWQ
DQMTAELKLT----AXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCSTREERALEKTE
PVTEEMEDPE--------------------------------------------------
---------------------GISESFFEPEHPGLVPGVCVKNLVKLFEPCGKPAVDRLS
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLIPPTSGTVLIGGKDIETSLDVVRQSLGMCPQ
HNILFHNLTVAEHILFYAQLKGKSWEESQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDSKVVILDEPTSGVDPYSRRSIWDLLLKYRS-RTIIMSTHHMDE-DLLGD
RIAIISQGL-YCS-TPLFLKNCFGTGFYLTL--RMRNIQNQTRDCKGTC-SCASKTSS-I
RCPACVDGLPSEQVLD--GDVSELMKMVHHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSESGP-------------------
VFVGGTHQKGENASLRHPCLGPREKARPIPQGSHSC-STEPGPHPEDQHQEELE-DHGAK
LNRGARLVIQHIEALLVKRFHHATRSHKDFLAQXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------XXXXXE
YPCGDS--TPWKTPPVSPNVSSLLQKQKWTPDNPSPSCKCSTREKLTMLPECPEGAGGLP
PPQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKSK----------FWV--NEQRYG
GISIGGKLPVFPITGEALVGFLSDFGQLMNVSGGPITREAAKEMSSFLKLLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRSSLSEDKNPEEYGITV-ISQPLNLTKEQLSEITVXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWAVIPMMYPASFLFDVPSTAYVALSC
TNLFIGLNSSAITFIL-LFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSNPFQWNLIGKNLVAMAIEGVVYLLLTLLIQHHFFLTQWV--AEPAKEPV-
-------AGEDDDVAEERQRIINGGNKTDILRLRELTKVYSGTSSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTSVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANWSIQSLGLSLYADHLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIKEGRAV-----VLTSHSM-----------
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHFNMLQFQVCSSSLARIFQLLVSHKESLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-THDLPLHPRAAGASPQAKVC---------------------------------
----------------------------

-------------------------------------MGCVRQ-IQLLLWKNWTLRKRQK
IRLVVELVWPLSLFLVLIWLRNINPLYSHHECHFPNKAMPSAGLLPWLQGIFCNMNNPCF
QSPTPGESPGVVSNYNNSI-----------LARVYQDFQELLMDAPESQHLGQVWAELRT
LSQLMNTLRTHPERVAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
FAHGVPDLALKDIACSEALLERFLIFSQRRGARTVREALCPLSQGTLQWVEDTLYANVDF
FKLIRVFSTLLDR-GSQGIDVRSWGKRLSDMSPRIQEFIHRPSVQDLLWVSRPLMQTGGP
ETIAQLMASLSALLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVESSD-GSATT
FCHALIRTLESNPLTKIAWRAAKPLLMGKILFTPDSPAAHK-ILKNANSTFEELGRFRKL
VKAWEEVGPQIWDFFDKSTQMTMIRNTLANPTVKDFLDRQFGEEGL-TVEAALDFLSNGP
QKSRVDDMANFNWRDVFNITDRTLRLVNQYREXXXXXXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIFIMHGR
ILHYSNPLILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGLIYLTLYLPHILCFAWQ
ERMTANLKMV----MSLLSPVAFGFGTEYLVRFEEQGLGLQWTNIGTSPVEGDGFSFLLS
MKMLLLDAALYGLLAWYL-DQVFPGEHGTPLPWYFLLQESYWLGTEXXXXXXXXXXXXXX
XXXXXXXXXX--------------------------------------------------
------------------XXXXXXXSFFEREVPGLVPGVCVKNLIKVFEPYGRPAVDRLN
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

GQITALLGHNGAGKTTTLXXXXXXXXXXXXXXXXXGKDIES-KDAVRQSLGLCLQ
HNILFHHLTVAEHLLFYAQLKGKSEEEAQLEMEAMLEDTGLHHKRNEETQDLS--GGMQR
KLSVAIAFTGDAKVVVLDEPTAGVDPYSRRSIWDLLLKYRAGRTIIMSTHHMDEADLLGD
RIAIISQGKLYCSGTPLFLKSCFGTGFYLTLVRRMKTVQAQLRGLEGARDNCVSPGCSG-
TCPACPDEPSLEQVLD--GDVNELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SF-RE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGYTQRTREDVSHRHPRAGQTETARHTSQASSL---EEAAPHPRAQPSGAPE---RAR
VHSGARLVLQHVQALLVKRCHHAVRSHQDFLAQIVLPATFVCLALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFISMDQPDNEQHSALTEVLLDKPGFGNRCLKK----------ELLP-E
YVCGN--ATPWMTPTMAPSVIHLLQWQEWTADNPSPSCKCSTRDKLTMLPECPPGAGGLP
PPQRTQRSGEILQDLTNRNISDFLVKTYPALIKSXXXXXX------------XXXXXXYG
GISVGAKLPALPLTADALVGFLSDLGQLMNVSGGPITREASKEMSSFLKHLETEDNVKVW
FNNKGWHALVSFLNVAHNAILRAHLLEDRDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAMVAICVILAMSFVPASFILYLIQERVNKAKHLQFLSGVSPTTYWVTNFLWDMANYSV
SAALVVSIFVGFQQ-AYTSPSHLPALVALLLLYGWAIIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXETHSSNPFRWDLLGKHLTALALEGVLYFVLTLLFQHHFFLTRRM--VEPTKEPI-
-------LDEDDDVAEERQRITSGGNKTALLRLNELTKVYSGSSSPAVDRLCVGVRPGEX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX

PF00005 // ENSGT00760000118965_5_Domain_3 (2197, 2356)

ILTSISDVRQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIESVALWCIKTLGLTLYADRLAGTYSRGNKRKLSTAIALV
GCPPLVLLDEPTTGMDPQARRMLWHTIMNIIREGRAV-----VLTSHRQEHPGG-----W
DECEALCTRLAIMVRGTFQCLGTTQHLKYKFGDGYIVTMKIRSPRDGSLPDLNPVEQFFQ
GNLPGSVQRERHHNLLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQAXVFVNF
AKQTE--THNLPLHPRAAGVRQAKV-----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERLRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQAILNFLYKGP
QESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMNVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAVAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFTGGAQQKRENINPQHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVIPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQVPLLLTQ-----------------STT--------
----------------------------

-------------------------------------MGFARQ-IRLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNVNPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDLQELLIEAPESQHLGQVWTELRT
LSQLMNTLRTHPERIAGRGIRIRDVLKDEETLTLFLTKNIGLSDSVIDLLINSQ-VHPEQ
FAHGVPDLVLRDIACSEALLERFLIFPQRRGVPAVREALCPLSQGALQWMEDTLYANVDV
FKLFRVLPRLVDG-GSQGVDLRSWGRILSDMSPRIQEFIHRPSVQDLLWVTRPLVQAGGP
ETFTQLMDSLSGLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPVYSYD-KRTTT
FCNALIQRLESNPLTKIAWRAAKPLLMGKILFTPDSPATRR-ILKNANSTFEELERVRTL
VRAWEEVGPQIWYFFDKSTPMAMIRDSLENPTVKAAFNRQFGEGGV-TAEAILSFLYRGP
REGRADDVASFDWRDVFNVTDRTLRLANQYLECLILDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDL-YPWTSSLPPHVRYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAY

PF12698 // ENSGT00760000118965_5_Domain_0 (667, 917)

LQDMVEQGITRSQAQAEVPVGIYLQQMPYPCFVDDA-FMIILNRCFPVFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSICLLTLFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTCFSRANLAAACSGVIYFTLYLPHILCFAWQ
DRMSADLKMA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DHVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PVTEEMEDPE--------------------------------------------------
------------------HPEGVNECFFERELPGLVPGVCVKNLVKTFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSIMTGLLPPTSGTVLVGGKDIETSLDAIRQSLGLCPQ
HNILFHHLTVAEHILFYAQLKGKPWEEAQLETEAMLEDTGLHHKRNEEAQHLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1792)

SGVDPYSRRSIWDLLLKYRPGRTIIMSTHHMDEADLLGD
RIAILAQGRLYCAGTPLFLKSCFGTGFYLTLVRKTKTVQSHGRGCAGTC-SCASKGVSG-
RCPACVNEMTPEQVLD--GDVSELVDVVHHHVPEAKLVECIGQELIFLLPSKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSGPGP-------------------
LFAGSTRQNKEDVSLRHPCSGPPGKARQTPQGTDGGCP-EPAP--------PLGGEGHGR
LNTGARLVAQHVQALLVKRFHHTVRSRRDFLAQIVLPATFVCLALMLSIIIPPFGDYPAL
TLHPWMYGQQYTFFSMDQPDSELLATLADVLVNKPGFGNRCLKG----------EWLP-E
FPCGN--STPWKTPSVSPDVTHLLQKQKWTADQPSPACRCSTREKLTMLPECPEGAGGLR
P-RRIQRSTEILQDLTGRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPPPPITAEALVEFLSDLGQLMNVSAGPFTREASTEMSAFLKHL

PF12698 // ENSGT00760000118965_5_Domain_2 (1792, 2078)

ETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLREASSPEEHGITV-ISQPLNLTKEQLSEITVLTTS
VDAAVAICVIFAMSFIPASFVLYLIQERVSQAKHLQFVSGVSPTTYWLTSFLWDMMNYAV
SAALVVSIFVGFQKKAYTSPDNLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALAC
ANLFIGINSSAITFVLELFENNQTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSSSPFQWELIGKNLAAMAAEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LIQHQFFFRRWT--TEPATEPI-
-------DNEDDDVAEERQRIIGGGTKTDILRLNELTKIYPGASSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNIADVHQSMGYCPQFDAIDDL
LTGREHLHLYARLRGVPAEEIKRVTDWSIQSLGLSLYADCLAGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNTIMGIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTTQHLKYKFGDGYIVTMKIKSPKDDLLPDLGAVEQFFR
GSFPGSVLRERHHNMLQFQVASASLARIFRLLVSHKDSLLVEEYSVTQTTLDQ--VFVNF
AKQQTEMTHDFPLHPRAAGASRQAKVPLLLLPEHCLRQILGSGT-QLVPKAQTCLLQKAP
RFQ----PPPPP-AMCHL-LCAEGLFSP

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QNPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGRIWTELHI
LSQFMNTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILMNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANLNWRDIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTNSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCLLLSTFFSKASVAAACSGIIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLMQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPIFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCASKSFST-
TCPAHVNDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRFPTRPCPNKTSSPGRTRQ-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNVSDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMITGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLLLLDEPTTGMDPQARRMLWNVIMSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASQQAQVPLLLTQ-----------------STA--------
----------------------------

------------------------------------------------------------
IRFVVELVWPLSLFLVLIWLRNVNPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLLDAPERQHLSQVWTELRT
LSQLMNTLRMHPERIAGRGIRIRDILKDEETLTLFLVKNIGLSDSVVYLLVNSQ-VRPEQ
FAYGVPDLVLKDIACSEALLERFLIFPQRRGGQMARGALCSLSQGTLQWMEDTLYANVDF
FKLFHVLPKLVDS-GSQGINLRSWGKIFSDMSPRIQELVHRRSVQDLLWVTRPLVQPGSP
ETFTRLVGTLSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGVDSTRKDPVYSYD-KTATT
FCNALIQNLESNSLTKIAWRAAKPFLMGKILFTPDSPATRR-ILKTANSTFEELERLRKL
LKAWEEVGPEIWYFFDKSAQMTMIRXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDKFESYDDEFQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPSHVKYKIRMDIDVVEKTNKIKDRYWDSGARADSVEDFRYF
WGGSEYLQHRVDQGITRSQAPAEVPTGV-LQQLPYHAQVDDX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXSLLSPVAFGFGTEYLARFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPXXXXXXXXXXXXXXXXXXXXXXXCSTREERALEKTE
PVTEEMEDPE--------------------------------------------------
------------------HPEGIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXSIMTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEVEAMLEDTGLHHKRNEEAQDLS--XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRTIIMSTHHMDEADLLGD
RIAIISQGRLYCAGTPLFLKNCFGTGFYLTLVRKMKTVQSQERGCEXXXXXXXXXXXXXX
----XXXXXXXXXXXXXXXDVTNLMDMVPPPVPKAKWG-EIGQKSIFLFPNKNSKQKPSP
RPXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXX-------------------
XXXXGSQQKRENSSLRHPCLGPGEGARPTPQGG------GPAPQPEGPPSP--QREGRGR
LNTGARLVLQHMQALLVKRFQHTVRIHKDFLAQXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-----X-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-E
FPCGN--STPWKTPSVSPDIAHLFQKQKWTQTSP-PSCRCSTREKLTMLPECPEGAGGLP
PPQRMQRSTEILQDLTDRNLSDFLVKTYPALIRSXXXXXX------------XXXXXXYG
GISVGGKLPGLPITGEALVGFLSDLGQLMNVSGGPVTREASKEMSAFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAVLRASLPADRNPEEYGVTV-ISQPLNLTKEQLS-ITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKARHLQFISGVSPTTYWLTNFLWDIXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNGTLLWFNAMLKKLLIIFPHFCLGRGLIDLALNQAVTDV
YARFGEEHSSNPFQWDLIGKNLVAMAAEGVVYFLLTLLIQYQFFFSPWT--TQPVKEPI-
-------IDEDDDVAEERQRITSGGNKTDILRLNELTKVYSGASSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVHRSMGYCPQFDAVDDL
LTGREHLYLYARLRGVPAEEIKRVTDWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNTIMSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFQCLGTIQHLKYKFGDGYIVTMKVKCPKDDVLPDLGPVERFFQ
GSFPGSVQRERHYNMLQFV-SSSSLGRIFRXXXXXXXXXXXXX--XXXXXXXXXXVFVNF
AKQQTE-IHDLPLHPRAAGARRQSK-----------------------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
RSATPGESPGIVSNYNNSI-----------LARVYRDFRELLMDAPESQHLGHVWTELQT
LSRFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLPDSVVYLLVNSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVYHAMCPLSQGTLQWVEDALYANVDF
FKLFRVLPTLLDS-SSQGINLRSWGRILSDMLPRIQEFIHRPSVQGLLWATRPLTQNGGP
ETFIQLTGILSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDATRKDPIYSYD-KRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERVRKL
FKAWEEVGPQIWYFFDKSTQMTMIRDTLANPAVKAFLSRELGEEGI-TAEAILNFLYTGS
PESRDDDMANFDWRDIFNIMDRTLRLVNQYLECLILDKFESYDDEIQLTHRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAY

PF12698 // ENSGT00760000118965_5_Domain_0 (667, 917)

LQDMVEQGITRSQAGAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKGIVLEKELRLKETLKNHGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRLTADLKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPVEGDEFSFLLS
MEMMLLDAALYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGMRDSFFERELPGLVPGVCVKNLVKMFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTCGTVLIGGKDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEETGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVVLDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNMQSQRRGCEGTC-SCASKGLSS-
SCPACVNDVTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTQDSDSGT-------------------
LFAGGTQQRWENASLRQPCLGPGEKAAQIPQGSNVHGP-APTAQPEGQPSP-PA-DPGTQ
LNVGARLVLQHVQALLVKRFHHAVRSRKDFLAQIVLPAAFVFLALMLSIIVPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSERLAVLADVLLNKPGFGNRCLKG----------EWLP-E
YPCGN--ATPWKTPSVSPNVTHLLQKQQWTPDDPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTNRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVIPVTGEALVGFLSNLGQIMNVSGGPITREASKEVS

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETQDNIKVW
FNNKGWHAMVSFLNVAHNAILRASLHKDKDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIKERVNKAKHLQFISGVSSTTYWLTNFFWDIMNYAV
SAGLVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFVLELFENNQTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YTRFGEEHSSNPFQWDLIGKNLAAMAVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LAQHHFFLTQWI--AEPSKEPI-
-------VDEDDDVAEERQRIISGGNKTDILRLNELTKIYSGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQSMGYCPQFDAIDDL
LTGREHLYLYARLRGVPAEEIERVANWSIKSLGLSLYADCLAGTYSGGNKRKLSTAMALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVRGAFRCMGTIQHLKYKFGDGYVVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IYDVPLHPRAAGASQQPKA----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELAWPLSLFLILIWLRNINPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGTVSNYNNSI-----------LARVFRDFQELVMKAPERQNLGHVWKELQT
LSQLMDTLRTHPERVAGRGIRIRDVLKDEETLTLFLTRNIGLSDSVVYLLVNSQ-VRPEQ
FAHGVPDLMLKDIACSETLLRRFIIFSQRHGAQTVRDAMCSLSQGTLQWVEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRSWGRIFSDMSPRIQEFIHRPSVQDLLWVARPLMQTGGP
ETFTQLMSVLSDLLCGYPEGGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILKNANSTFEELERLRKL
VKAWEEVGPQIWYFFDKSTQMTMIRDTLENPTVKAFLNNQLGEEGI-TVEAVLNFLDRGP
RENQANDVANLNWKDVFNITDHTLRLASRYLECLILDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSALPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMIERGITRSQAQVEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLTFSTATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKMA----VSLLSPVAFGFGTEYLARFEEQGLGLQWNNIGRSPMEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEACSTREERALEKTE
PITEEMEDPG--------------------------------------------------
------------------HPEGINDSFFERELPGLVPGVCVKNLVKIFDTYSRPAVDRLN
ITFYENQITAFLGHNGAGK

PF00005 // ENSGT00760000118965_5_Domain_1 (1100, 1222)

TTTLSILTGLLPPTSGTVLIGGKDIETSLDEVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGGAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRTGYEGNC-SCASEGFSS-
RCPAHIDEITPEQVLD--GDVNELMDMIQHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEDTLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGTHQKRENVSLQHPWLGPKDKARQIPQGSDGCSA-EPAPPRGGQPSSEPEPEHRSR
LNTGAPLLLQHVQALLIKRFHHTVRSHKDFLAQIVLPATFVFLALMLSLIVPPFGEYPAL
TLHPWMYGQQYTFFSLDQPGSEQLAALADILLNKPGFGNRCLKE----------EWLP-E
YPCVN--STPWKTPSVSPNITHLFQKQKWTPEDPSPSCMCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEVLQDLTNRNISDFLVKTYPSLIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVLPITGVNVSGVCKQPGDLGRTFDGPITREASKEMPAFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRTSLHKDKNPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVSPTTYWLTNFLWDIMNYAV
SAALVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDIPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLLRFNAMLRKLLVIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSTNPFQWDLIGKNLVAMAAEGVVYFLLTLLIQHHFFLTRWI--AEPAKEPI-
-------IDEDDDVAEERQRIISGGNKTDILRLNELTKIYSGTSSPAVDRLCVGVRPGEC
FGLLGV-NGAGK

PF00005 // ENSGT00760000118965_5_Domain_3 (2173, 2293)

TTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQNMGYCPQFDAIDDL
LTGREHLYLYARLRGVPADEIERVANWSIQSLGLSLYADRLVGTYSGGNKRKLSTAIALM
GCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKCKFGDGYIVTMKIRSPKEDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFRLLISHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQTE-IHDLPLHPRAAGASRQAKVLLLLFHSPLSEA----DP-QLRDWYAGSEGPQGP
DMPPTE-SPP------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQELLMNAPESQHLGHIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVHLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERLRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDILGNPTVKDFLNRQLGEEGI-TAQAILNFLYKGP
QESQADDMANLNWRYIFNITDRTLRLVNKYLECLVLDKFESYNDETQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMNVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASVAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLMS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIHDSFFEREHPGWVPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAIRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSHRKGSEGTC-SCASKSFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFTGGAQQKRENINPQHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPE-CPGPQ
LNTGAQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIIIPPFGEYPAL
TLHPWMYGQQYTFFSMDEPGSEQLTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTEANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVIPVTGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLQHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKGPI-
-------VDEDDDVAEERQRIITGGNKTDILRLYELTKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKSKFGDGYIVTMKIKSPKDDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQNE-IHDLPLHPRAAGASRQAQD----------------------------------
----------------------------

-------------------------------------MGFARQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLILIWLRNTNPLYSQHECHFPNKAMPSAGMLPWLQGMFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVFRDFQELLMEAPERQHLGHVWKELQT
LSQLMDTLRTHPERVAGKGIRIRDVLKDEETLTLFLMKNIGLSDSVVYLLVNSQ-VRPEQ
FAHGVPDLMLKDIACSEALLKRFIIFSQRHGAQTVRDAMCSLSQGTLQWVEDTLYANVDF
FKLFRVLPTLLDS-SSQGINLRFWGRILSDMSPKIQEFIHRPSVQDLLWVARPLMQTGGP
ETFTQLMSILSDLLCGYPERGGSRVFSFNWYEDNNYKAFLGIDSTRKDPIYSYD-KRTTT
FCNALIQSLESNPLTKIAWRAAKPLLMGKILFTPDSPAARR-ILQNANSTFEELERLRKL
VKAWEEVGPQIWYFFDKSTQITMIRDTLENPTVKGFLNSQLGEEGI-TAEAVLNFLDRGP
RESQADGVANFNWRDVFNITDRTLRLASRYLECLILDKFESYDDEIQLTQRA-LSLLEEN
RFWAGVVFPDM-YPWTSALPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFAYLQDMIEQGITRSQAQVEVPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSNPFILFLFLLAFSTATIMQCFLLSTFFSRASLAAACSGVIYFTLYLPHILCFAWQ
DRMTADLKMA----VSLLSPVAFGFGTEYLARFEEQGLGLQWSNIGNSPMEGDEFSFLMS
MKMMLLDAALYGLLAWYL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PITEEMEDPE--------------------------------------------------
------------------HPEGINDSFFERELPGLVPGVCVKNLVKIFEPYSRPAVDRLS
ITFYE

PF00005 // ENSGT00760000118965_5_Domain_1 (1086, 1268)

NQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLIGGKDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHILFYAQLKGKSWEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGGAKVVILDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRAGCEGTC-GCASEGFSS-
RCPAHVDEITPEQVLD--GDVNELMDMVRHHVPEAKLVECIGQELIFLLPNKNFKQRAYA
SLFRE-LEDTLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGTQQKRENVSLRHPWLGPREKAREIPQGSNGCSA-EPAAPPGVQPSSEP--EQRRR
LNAGAQLLLQHVQALLVKRFHHAVRSRKDFLAQIVLPATFVFLALMLSIIVPPFGEYPAL
ILHPWMYGQQYTFFSLEQPGSEQLAALADVLLNKPGFGNRCLKE----------EWLP-E
YPCGN--STPWKTPSVSPNITHLFQKQKWTPENPSPSCMCSTREKLTMLPECPEGAGGLP
PPQRIQRSTEILQDLTNRNISDFLVKTYPALIRGSLKSK----------FWV--NEQRYG
GISIGGKLPVLPINGEALAEFLSHLGQMMNVSGGPITREASKEMPAFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHSAILRACLPKDKDPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFAMSFVPASFVLYLIQERVNKAKHLQFVSGVNPTTYWLTNFVWDIMNYAV
SAALVVGIFIGFQKKAYTSPENLPALVALLMLYGWAVIPMMYPASFLFDIPSTAYVALSC
ANLFIGINSSAITFILELFENNQTLLRFNAMLRKLLIIFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFQWDLIGKNLVAMAAEGVVYFLLTLLTQHHFFLTRWI--AEPAKESI-
-------IDEDDDVAEERQRIISGGNKTDILRLNALTKIYSGTSSPAVDRLCVGVRP

PF00005 // ENSGT00760000118965_5_Domain_3 (2158, 2356)

GEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATIAGKSILTNISDVHQNMGYCPQFDAVDDL
LTGREHLYLYARLRGVPADEIERVANWSIQSLGLSLYADRLVGTYSGGNKRKLSTAIALM
GCPPLVLLDEPTTGMDPQARRMLWDTIVSVIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGTFQCLGTIQHLKYKFGDGYIVTMKIRSPKEDLLPDLNPVEQFFQ
GNFPGSVQRERHYNMLQFQVPSSSLARIFRLLIAHKDSLLIEEYSVTQTTLDQ--VFVNF
AKQQAE-IHDLPLHPRAAGASQQPKV----------------------------------
----------------------------

-------------------------------------MGFVRQ-IQLLLWKNWTLRKRQK
IRFVVELVWPLSLFLVLIWLRNANPLYSQHECHFPNKAMPSAGMLPWLQGIFCNVNNPCF
QSPTPGESPGIVSNYNNSI-----------LARVYRDFQEILMNAPESQHLGRIWTELRI
LSQFMDTLRTHPERIAGRGIRIRDILKDEETLTLFLIKNIGLSDSVVYLLINSQ-VRPEQ
FAHGVPDLALKDIACSEALLERFIIFSQRRGAQTVRYALCSLSQGTLQWIEDTLYANVDF
FKLFRVLPTLLDS-RSQGINLRSWGGILSDMSPRIQEFIRRPSMQDLLWVTRPLMQNGGP
ETFTKLMGILSDLLCGYPEGGGSRVLSFNWYEDNNYKAFLGIDSTRKDPIYSYD-RRTTS
FCNALIQSLESNPLTKIAWRAAKPLLMGKILYTPDSPAARR-ILKNANSTFEELERVRKL
VKAWEEVGPQIWYFFDNSTQMNMIRDTLGNPTVKDFLNRQLGEEGI-TAEAILNFLYKGP
RESQADDMANFDWRDIFNITDRTLRLVNQYLECLVLDKFESYNDETQLTQRA-LSLLEEN
MFWAGVVFPDM-YPWTSSLPPHVKYKIRMDIDVVEKTNKIKDRYWDSGPRADPVEDFRYI
WGGFA

PF12698 // ENSGT00760000118965_5_Domain_0 (666, 917)

YLQDMVEQGITRSQVQAEAPVGIYLQQMPYPCFVDDS-FMIILNRCFPIFMVLAW
IYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGR
ILHYSDPFILFLFLLAFSTATIMLCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAWQ
DRMTAELKKA----VSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDKFSFLLS
MQMMLLDAAVYGLLAW

ENSGT00760000118965_5_Linker_0_1 (917, 1077)

YL-DQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTE
PLTEETEDPE--------------------------------------------------
------------------HPEGIYDSFFEREHPGWIPGVCVKNLVKIFEPYGRPAV

PF00005 // ENSGT00760000118965_5_Domain_1 (1077, 1222)

DRLN
ITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQ
HNILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLS--GGMQR
KLSVAIAFVGDAKVVILDEPT

ENSGT00760000118965_5_Linker_1_2 (1222, 1786)

SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGD
RIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTC-SCSSKGFST-
TCPAHVDDLTPEQVLD--GDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYA
SLFRE-LEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGP-------------------
LFAGGAQQKRENVNPRHPCLGPREKTGQTPQDSNVCSPGAPAAHLEGQPPPEPE-CPGPQ
LNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPAL
TLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRCLKE----------GWLP-E
YPCGN--STPWKTPSVSPNITQLFQKQKWTQANPSPSCRCSTREKLTMLPECPEGAGGLP
PPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSK----------FWV--NEQRYG
GISIGGKLPVVPITGEALVGFLSDLGRIMNVSGGPITREASKEIP

PF12698 // ENSGT00760000118965_5_Domain_2 (1786, 2078)

DFLKHLETEDNIKVW
FNNKGWHALVSFLNVAHNAILRASLPKDRSPEEYGITV-ISQPLNLTKEQLSEITVLTTS
VDAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSV
SAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSC
ANLFIGINSSAITFILELFENNRTLLRFNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDV
YARFGEEHSANPFHWDLIGKNLFAMVVEGVVYFLLTL

ENSGT00760000118965_5_Linker_2_3 (2078, 2150)

LVQRHFFLSQWI--AEPTKEPI-
-------VDEDDDVAEERQRIITGGNKTDILRLHELSKIYPGTSSPAVD

PF00005 // ENSGT00760000118965_5_Domain_3 (2150, 2292)

RLCVGVRPGEC
FGLLGV-NGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDEL
LTGREHLYLYARLRGVPAEEIEKVANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIALI
GCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAV-----VLTSHS-----------M
EECEALCTRLAIMVKGAFRCMGTIQHLKS-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------