Query Results 

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPD--QSIQELPLFFTFPP---PG--DTWELAFI
PSH--SDAARTITQTVRREL-------VINMRVRGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHTFNHSKDPLPLAVKYHLRFSYTRRNYVWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATHQLFQNLT-VIA
KRFPYPPFISDPFLAAIQYQLPLLLMLSFTYASLTITRAVVQEKERKL------------
---------------------------KEYMRMMGLSNWLHWSAWFLLFFLFLLVAVSFM
TLLLCIKVK-KD----VAVLASSEPSLV----------------------------LAFL
VCFAVASISFSFMVSTFFSKA---NMAAAVGGFLYFLTYIPYFFVAPRYNWMTLNQKLCS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVSVDDDFCFGQVLGMLLLDSVLYG--
VATW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FCV------LPSY-WFGTPRTVIGKEE-EDNDPEKALG
TEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDKVAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGQAYISGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSRHK-CPEEVKQMLHILSLEDKWDSRSRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAVWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGVSQ---LVYHHVPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFTKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DMQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPTDGIGAL-
----IEEEHAAVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCVTLAL
LAINYSSEI-----FDDPILKLTLGAYGRTVV---PFSVSGTSR-------LDQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTTVTA
LFNNQAYHSP-----------------------------ATTLAVVDNLLFKLLCGPQAS
IVVSNYPQPRSALQAAKDQ-FKE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERTVQAKHVQFVSGVRMATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIEYRENFYAWKAP
GVGRF--VASMA---------------ASGCAYLALL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFLCAF-----
-RRRQ---V--LAELCTRTSVLPEDQDV-----ADERSRVLAPSLDSL--LDTPLVIKEL
SKVYEQQ--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DKVSLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEDSITSGDAFVG
GHSISSDIGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------EGQQ---EALQEFKAFVDLT----F--------
-S-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLGFAHLQPPATESR-------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MELLT
LNQFAVLLWKNFTL---KRRHVINLILEVFSALVFAIMLLLFRAITE-TKIN--------
----------------------GPYNYTS--QPINTLPTFIQNA--------NEWELIYI
PSN--ISVVKEITENVKKNL-------NISIRVRGFSSET-------EFEKYILYDYS-S
YNVLAAIVFDHDFKNSNDSLPLQVKYHLRFIRVQRTVW--------WPDRPGWKTDFLFP
NR-PSVGPRNPNYP--EGGSPGYIREGFLVVQYALDKAIMLYHENTTGQKLFDGIS-IFV
QRFPYPAYCHDGLLWIISSFLPLIFMLMFSPIVLSNIRYIVWEKEKRLK-----------
----------------------------EYQLITGLRNWMIWAAYFFTSFLWYIIIIILI
CVLFFA--KIFN----KPIFRYSDSGFI----------------------------FLFL
MCYAVASIFFGFMLSTLFSKA---HLAASAGNILFFASFFPFNFIAQRYGEITLTYKVAA
CLSSNVALALGINLLLKLEVR-QIGAKWHNFWTPASLEDNLVFGYLFGMLLLDAFLYG--
LVAWYVETVFPGRYGLPQPWY-FFL------KHSY-WFGKPRIRRK-K--EI-NGPEGIQ
STYFEDEPIHLVAGI-QIKH-LH-----KEYEDNVVVNNLSLNLYE---EQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 912)

TT--ILSILTGRFPP-TKGKAYIDGYDISSNIIEIRKNLGFCPQHDLFFDDLTVSE
HLFFYSVIKGIPQRK-CTVETDHMLSIFNLLEKHDAFPQELSGGMKRKLSIIIALMGSSK
---V-LIFDEPSSGMDPTSRRVFWHLLQQYKHNRTILLTTQYMDEADILGDRIAIMIKGT
LRCCGSSVFLKRK-YGAGYHIVMEKEPHCDVEKMSA---LIQYYVPDATLE---NDIGDE
LSFMLPKKYTTRFK---D-LFNELEMKQKDLGIVSFVASITTMEDVYLK--ANKLAASEW
NIHAI--HSPYLKTQN-IKRDKKQSMDMPIDY------------------ERPL------
--SSSLNEIANIKFNTGFPLYFQ-QFCSMFIKRALFSLRNWKLLL-LQIIVISVVTTYLL
ISLDLG-------HGDVPARKMDLSQYGQTTV---PYSISGNSD-------LAMKLIKNL
EIFLKSKNQELRE-IP-----GNVNNYL-----MQSKECHDFCIIAFSIKVEEDKTVLTI
LFNNEAYHSA-----------------------------ATSLAVLDNILFMSLSGLNAS
ITVSNKPQPL--PIYGSNM---V-----PINGLQIVLCLAFGISVVV---------GN--
FCLQTVIERINKSKHIQFVSGVYVLTYWLSALLWDLISFFIP-----CCLLL--------
GVFTLCEVEAFVVNYHFLD-TLLILMLYGWCVVPFMYLGSFLFSNSTAAY------IKLT
LFNYFST--------IFSIVIHSIIKHHE---TDFHISTRNFVNNVLMVLPTYNFAMSIS
RFFD-------------DYEVKK-LCAKQF--QSVYLD----CSKP--FVQNNVYSFGEH
GIAKF--LITLA---------------VMGLLFLLLLLSLETAL-WSLKNFIFHNIVSN-
VYKKIMK-RKATVSNQ--VIEDCEDEDV-----KNERNRAQKMLQ---TLEESPLLLQEL
KKVYFKC--PAVQAVRNISLVVNKSE-CFGIFGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEQTTTSGVVLID
GININENIRKVRS-RIGYCPQLDSMLNHMTGRELLIMYARL-WGVPESNICKYVEAFLHS
VHLE-AYADKFVYTY---SGGHKRRLNTVIALM---------GKSSVVFLDEPSAGMDPV
ARHLLWDTITWICKTGKAIII--TSHSME----ECEALCT-----RLAIMVKGRFIYLGS
PRHLRNKYGNICTLTAKINI-------DKDE---EKLQMFKNFIEKT----F--------
-P-GNII-----NQEYQGTIICHIPSKEIRWGK--VFSILEEATVLFNLEDYSVSQITLE
EIFLTFADIDRRENDDQINLL---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MTM
FRNLKLLLWKNFIL---KKRKTLVTVLEILMPLLFCAVIIYLRFGSL-PRKR--------
----------------------PPVDYNV--TDITSLPEFFNQFP---LK--NKFQLVYI
PSK--SETLKNITEMVKDFF-------TVEFEVLGYSSVP-------LFEKYIIQDPK-A
FYVLAGIVFYHDFNDSMEPLPLEVKYYLRFSFFQRNYLSLR-LILQQDDMQGWLTSFLYP
PN-LSQEPRDYGVS--EGGAPGYYQEGFLAIQHATDRAIMWHHAPAETTGLFQSLT-VLL
KRFPHGAYVRDLFFLVLQNEFPLFLMLSFICIELITINSIVLEKERKLK-----------
----------------------------EYMCMMGLHSWQHWVAWFIVFFISASIVVSFM
TFLFCIEFD-K-----SAVFGNSDPSLI----------------------------FVFL
MCFAIATIFFAFMISTFFQKA---HVATASGGIIFFFTYLPYLYLTFTYTQRSLFQKITF
CLFSNVAMALGVRLISTYEAR-GTGIQWRNMG---HIGGEFNFTQVLLMLLLDSVIYG--
LVAWYVEAVFPGEYGTPKPWY-FFL------MPSY-WSGEPISLRNPV-LDLEDPQQALG
NKFIQDEPTNLIKGI-EIQH-LYKVF-YKGRDEHVAVKDLTVNLYQ---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TCSILTGLITP-SSGQAFINGYEISQDMLQIRKTMGWCPQHDILYDNLTVAE
HLYFYAQLKGLPRQK-CPEEVKRMLHVLGLEEKRDSRSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPTAGVDAISRRAIWDLLQQHKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKEK-YGAGYYITLVRKPRCDTEKISL---LVYQHIPNAVFQ---SSIGEE
LTFILPKESTHRFE---A-LFTDLELRQEELGIASFGVSVTTMEEIFIR--VNKLMDSDI
DLQII--KLPSFHSHP-LVSRVPVN---------R-------IK--RLHSRI--------
--FSIP-SGLPIHPNTGFSLLCQ-QFYAMFLKRATYSWRNWIMMLSIQILVPLVILSISL
SFLNFDI-S---M--DNSPLELTLKSYGQTIV---PFYISPNSR-------LGPQLLDHL
TDVLMAEDQNPLE-LQ-----SPVEPFLLKKLEEEPEVFDKNYLVAISFDDVGNHTIVTA
LFNNQAYHST-----------------------------AQVLALVDNILFKLLSGPRAS
ITVLNHPQPQSSMEIVEDI-LYE-----GPKGHYLVINLLFGMAFLS---------SS--
FSILTVKERGLKAKQVQFISGVHVAMFWLSSLLWDLLSFLVP-----SLLLL--------
VVFLYYDEEAFTHKENVPA-VFLMLMLYAWAIIPFIYLTSFCFDNAGNAC------VKLI
IMLTFLS--------IGPF--VL-VSVTSEKELGYTAIS-ESLDNMFLPLPGHCLGMALS
NLYY-------------NFELQK-FCKVKSLDQIECSKV-----SEGYVVQEDIYAWESL
GTGKY--LTVLA---------------ILGLVYLILLFLTETNVLWELKSR-FSG-LS--
-WKQK---MEKQV-VLQNAESVPGDQDV-----EEEAKMIKNSWEDLC--KKNPLVLKEL
SKVY-SR-KVPPLAVNKVSFAVRAEE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTIFKILTGEESITSGDAFVN
SISVSSDLRKVRQ-WIGYCPQVDALLDHMTGRETLVMFSRL-RGIPERHISSCVDQILDD
LLMY-TYADKLVKTY---SGGNRRKLSAGIALL---------GEPVVIFLDEPSTGMDPV
ARRLLWGTVARARKSGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVGLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDDLSWAK--VFGIMEQAKATYVLEDYSVNQVSLE
DIFLSFSCPVPPARGSNRQERAKPADPTFPC------PPLSPSSSQQPSPPPTPPPTPSS
SQPFSWSPTPIPFR----PSSW-----------------SSSQPPSL---PRSPPASQPP
SP--HPSKTALL---------------------------------

---------------------------------------------------------MAV
LRQLSLLLWKNYTL---QKRKVLVTALELLLPLLFSGILIWLRLKIQSENVP--------
----------------------KATIYPS--QSVRELPLFFSFPP---PG--DAWELAYI
PSQ--SEAVKTITETARRAL-------VINMRVRGFPSEK-------DFEDYIKYDNR-S
SNVLAAIVFEHTFNHSKDPLPLAVKYHLRFSYTRRNYMWTQTGSFFVKETEGWHTTSLFP
LF-PNPGPREPASP--DGGEPGYIREGFLAVQHAVDRAIMQYHTNASTHQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFIYTSLTIVRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWTAWFLLFFLFLLVAVSFM
TLLFCVKVK-KD----VAVLAHSDPSLV----------------------------LVFL
VCFAISSISFSFMVSTFFSKA---NMAAAVGGCLYFFTYIPYFFVAPRYNWMTLSQKLFS
CLLSNVAMAMGAQLIGKFEAK-GTGVQWRDLLSPVNVDDDFSFGQVLGMLLLDSVLYG--
LVTWYVEAIFPGQFGVPQPWY-FFI------TPSY-WCGHPRTVLGKEE-EDHDPEKALK
TEYFEAEPENLVAGI-KIKH-ISKVF-RVGNKGKAAVKDLNLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYINGYEISQDMAQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHILGLEDKRDSRSRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPTSGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPESISR---LVYHHIPNASLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGTM-DPTDGIGAL-
----IE-DCTAIKLNTGLTLYCQ-QFLAMFLKKATYSWREWKMVA-AQVLVPVMSITLAL
LAINYSSEI-----FDDPILKLTLGEYGRTVV---PFSVPGTSR-------LDQQLAEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVITA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
ITVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----TLLLL--------
VVFKAFDVHAFTRDGHVAD-TLLLLMLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-RTLDRIFLVLPNHCLGMAFS
SFYE-------------NYETRR-YCTSSEVAAH-------YCRKYNIQYQENFYAWSAP
GVGRF--VTSLA---------------ASGFAYLILLFLIETDLLWRLKTCICAF-----
-RRRR---G--LMEVYTRPSALPEDQDV-----VDERNRILAPSLHSP--LDTPLVIKEL
CKVYEQR--VPLFAVDKISLAVQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGEETLTSGDAFVG
GYSIRSDIGKVRQ-RIGYCPQFDALLDHMTGRETLVMYARL-RGIPERHISAYVENTLRG
LLLE-PHASKLVRTY---SGGNKRKLSTAIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------DGQQ---EALQEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDDLSWAK--VFGVLEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPAEDEGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------LLT
LNQFSVLLWKNFTL---KRRQFFTSTLEVLTALVFPVMILLFRTLTA-IKVV--------
----------------------GPYNYTS--HPINTLPSYLKNP--------EEWELTYV
PSN--IDVVTEITENMKRNL-------NISVKVQGFTSEM-------ELEKYIKYDYG-S
RKVLAAIIFYCNFKSSSDPLPLEIKYHLRFVRIQRSLM--------WPDRLGWKTSLLFP
VH-PPVGPRNADYD--DGGSPGYIREGFLAVQHALDKAIMLYHESSASQKLFNSIS-IFI
QRFPHPAYSHDGLIWITSSFLPLMFILMFSPTVLSIMRSIVWEREKRLK-----------
----------------------------EYQLIIGLKNWIIWAAYFFTFFFFYIIIISMI
CVLFSA--KIFS----EPIFRFSDCSFI----------------------------FVFL
MCYAIASIFFAFMVSTFFNKV---RLAASAGSLLYFASFFPFNAITQFYGELTLTRKVAA
CLSSNVALALGISRLLKLELR-QIGIRWDNIWTPVNLEDNLMFGHILLMLLLDAFLYG--
LVTWYIETVFPGQYGVPQPWY-FFL------MHSY-WFGDPKIRRK-K--EEMKSCGETP
NKYFEAEPANLVAGI-QIKH-LYKVFVSKEFGDKVVVNNMSLNLYK---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITILLGQ-N
GAGKTT--ALSLLIGYYPP-TRGEVYIHGFDISKNLFEIRKHLGFCPQHDILFNDLTLLE
NLFFYSVVKGLYQKV-YSMEIDHMLSTFNLLEKRNTFSRSLSGGMKRKLAIIIALIGGSQ
---V-MILDEPSSGMDPVSRRATWDLLHQYKQDRTILLTTHYMDEADLLGDRIAIMVKGT
LQCCGSSVFLKEI-YGAGYQIVMEKESHCDVEKISA---IIH------------------
------------------------------------------------------------
------------------------------------------------------------
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---------------------------------------------

---------------------------------------------------------MAV
LRQLTLLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QSIQELPLFFSFPP---PG--GTWELAYV
PSH--SDAARTITETVKREF-------MIKMRVHGFSSEK-------DFEDYIRYDNH-S
SSVLAAVVFEHSFNHSQDPLPLAVKYHLRFSYTRRNYMWTQTGNIFLKETEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIREGFLAMQHAVDKAIMRYHANTSAQQLFQKLM-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLNSWLHWSAWFLMFFLFFLIVVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDNFCFGQVLGMLLLDSALYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWH-FFL------MPSY-WCGNPRTVVGKEE-EGSDPEKALR
NEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKMGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSLLTGLFPP-TSGHAYIHGYEISQDMAQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKSDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGAL-
----IEEEEVLVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCLTLAL
LAIHYTSEI-----FDDPLLKLSLNEYGRTVV---PFSVPGTSR-------LAQQLSENL
RDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDRGELTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEISNYPQPRNTLQVAKDH-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWFSALLWDLISFLVP-----SLLLL--------
VVFQAFNVHAFTRDGHMAD-LLLLLMLYGWAIIPLMYLMSFFFSAASTAY------TRLT
IFNILSG--------IATFIM---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSELAAH-------YCKKYNIQYQESFYAWSTP
GVGKF--VTSMA---------------ASGGIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-RRRW---T--LAELQNRTSVLPEDQDV-----AEERSRILVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLINACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---DALEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

ILELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPE--QSIQQLPLFFSLPP---PG--GSWELAFI
PSH--SDAARTITETVRREL-------VINMRVHGFSSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHAFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGNIFLRETEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIHEGFLAVQHAIDKAIMHYHANASAHQLFQKLT-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLSIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFFLIMVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYYFTFSPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVIGKEE-EDSDPEKTLR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKVGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSMLTGLFPP-TSGHAYIHGYEISQDMIQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGMSLQK-CPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKNDRTILLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LIHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGAL-
----IEEEEAMLKLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPVTCITLAL
LAINYTSES-----LDDPPLKLSLDEYGRTVV---PFTVSGTSQ-------LHQQLSEHL
KDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDSGEKTEVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEISNYPQPRSTLQVAKDQ-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVQAKHIQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFQAFDVQAFTRDGHLAD-LLLLLMLYGWAIIPLMYLTSFFFSAASTAY------TRLT
IFNILSG--------IATFIV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCVGMAVS
SFYE-------------NYETRR-YCTSSWVAAS-------YCKKYNIQYQENFYAWSTP
GVGKF--VTSMA---------------VSGCIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-QRRW---T--LAELQNRTSVLPEDQDV-----ADERSRVLVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSEIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLISACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTAIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---EVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDFLT
FNQFSVLLWKNFTI---KRRHYINLLFEVLTAVVFPMLLLLFRSFAT-IQVA--------
----------------------GPHYYKP--LRISGLPSFLQNP--------QEWELIYV
PSN--INVVKEIIESMKRNL-------NISIKVKGFYSES-------EFENYVKYDYK-S
QKVLAAIVFDNDFENINDSLPLQVKYHLRFVRIPRTIQ--------HSGPSDWKTSLLFP
LH-PFSGPRNPNNQ--DGGSPGYITEGFLAVQHALDKAIMLYHGGRAAQKLFDGIS-VLI
QRFPHPAYSEDRLILSLNGFLPLMFILMFSPTVLSTMRTLVSEKEKRLK-----------
----------------------------DYQLIIGLRNWMIWASYFLVVFFFYIIIISLI
CVLFFA--KIFN----EPIFRYSDSSFI----------------------------FVFF
MCYAIASIFFGFMVSTFFSKA---HLAASAGSFLYFASFFPFKSVIGNYGQLTITNKVAA
CLSSNVALALGINLLLNLEIK-EIGLKWNNLWKPASLEDNLILGYMMGMLLLDAFLYG--
LVTWYVEAVFPGQYGVSQPWN-FFL------MRSY-WYGRPGIRRK-E--EDMKGYGRTQ
SKYFEAEPTGLVASI-QIKH-LH-----KEFGAKVAVNNMSLNLYK---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGE-N
GAGKTV--TLSILTGCHPP-TRGEVYVNGYPISKNLNDIRKNFGFCPQHDLLFNDLTLSE
HLYFYFMLKRKCREM-YPVEADHMLSTFNLLEKCNTMSKSLSTGMKRKLSVMIALIGDSE
---V-VILDEPTLSMDPISQRATWDLLHQHKQDRTILMTTHHMDEADILGDRIAIMVKGT
LHCCGSSVFLKQI-YGATYRIVMEIDPQCDVEKLSA---VIQSHIPHATLE---ECTGAE
LSFILPKEYIHRFE---A-LFNDLKEKKSELGITSFDASVTTMEEVFHK--VNKLARSQM
DSPSS--LSSSLEGQR-KRQDMKRNRIMPRNY------------------NTTV------
--FSRLSEIATTEFNTGFPLYRQ-QFYCMFIKRALFSLRYWKLVL-LHISVIVVVTTYLL
TAQNL--------RSEVPVREIDLSQYGQTIV---PYSVSGKSD-------LAMDFIKNL
KIFLALANQQLHE-VQ-----GHVTNDI-----LKIKKFNDFSIIAFSIDVGKNKTLLTI
LFNNEAYHSA-----------------------------TTSLAVLDNILFMSLSGPSAS
IKVSNKPQPL--PLYISHE---V-----PTDGSRIVLHLAFGMAVVV---------AS--
FGLQTVTERITKAKHIQFVSGVYVLIYWLSALLWDLIYYFIS-----CCLLL--------
GVFKYCELRAFVEDYNFLD-TMLIFMLYGWSAVPLMYLGSYLFSSSTAAY------IKLT
LFNYFST--------VVSIVIDSIIHVIG---NEISDFTKVFISNVLVMLPSYNFAMGVS
RFLD-------------DYEVKR-LCTQEI--QNVYVD----CRKK--STKNSVYNFGEN
GIAKY--LISLA---------------VLGLFYLLLLFCLETTS-WRLQNFLFQKIVSN-
VYNIFIKGKKAKESMH--VSNEYVDENV-----ENERKKALAQSP---KLKNSPLLLREL
VKTYYKC--RVVHAVRNVSLVVKN

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

SE-CFGLFGLNGAGKTTILKMLTGDETISSGVVLID
GISLIENIRKVRS-RIGYCPQSNPLLNHLTGRELLIMYARL-QGVPEPNICKYVEIFLLS
MHLE-NHADKFVYTY---SKENKRKLSTVIALM---------GKSSVVFLDEPSSGMDPI
ARRLLWDTVTWMCKAGKTIII--TSHSMG----ECEALCS-----RLAIMVNGKFKCLDR
PQQLKNKFSDIYTLTVKIKI-------DKNE---NKQKEFKEFIATT----F--------
-P-GNIV-----NQEYQGIIYYHIPRNEICWGK--VI-----------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------KRKVVVTVLEILLPLLFSGILIWLRLKIQSENVP--------
----------------------SATTYPA--QSIRELPLFFTFPP---PG--DPWELVYI
PSR--SSAVRTIADTVKKAL-------VINLRVRGFPCER-------DFEEYIRYDNH-S
SSVLAAVVFEHTFNHSRDPLPLAVKYH-RFSYTRRNYMWIKTGSFFLKETEGWHTTSLFP
LF-PNPGPREPAAP--DGGEPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------
--------------------------XXEYMRMIGLSSWLHWSAWFLLFFLFLLVTVSCM
TLLFCIKVK-EG----VAVLARSDPSLV----------------------------LAFL
LCFSVSTIAFSCMVSAFFS-----------------------------------------
--------------------R-GTGLQWRDLLSPVNVDDDFSFGQVLGMLLLDAVLYG--
LGAWYVEAVCPGQFGVPQPWY-FFV------MPSY-WCGSPRTTSGKED-GDDDPEKALR
KEFFEAEPEDLVAGI-KIKH-LSKVF-QVGSKGKAAVRNLXXXXXX---XXXXXXXXXXX
XXXXXX--XXXXX

PF00005 // ENSGT00760000118965_2_Domain_1 (794, 959)

XXVLPI-SSGQIYVNGYDVTENTAAAQKGMGWCPQHNILFYDLTVAE
HLCFFAWLKGLSRQK-CQEEVRQMLRALGLEDKRDTLSKFLSGGMQRKLSIGIALVAGSE
---V-LMLDEPTSGLDAVSRRAVWDLLQQQKSDRTILLTTHFMDEADVLGDRIAIMAKGE
LQCCGSPLFLKEK-YGAGYHMTLVKEPHCDPEAVSQ---LIYHNIPNATLE---SSAGAE
LSFILPKESTHRFE---M-LFTKLEQQKQELGIASFGASVTTMEEVFLR--LGKL-NTSM
DIQAI--QLPALQYQH-ER-VSDWAVDT---------------HLCGVM-DPNGGGPL--
----VEEDCSTVQLNTGLALHCQ-QFWAMFVKKALYSCREWKVVA-AQVLVPLTCLTLAL
LAVNYSSEI-----LDDPSLPLTLGEYGTTIV---PYSAAGTSQ-------LHQQLSEHL
RDMLQAGGQEPRE-VL-----GDLEEFFIFRASVEGGGFNERCLVATSFRDVGEQTVITA
LFNNQAYHSP-----------------------------ATALAVVDNLLFRLLCGPRAT
ITVSNHPQPRSTLQAAKDQ-FNE-----SRKGFNIALNLLLAMAFLA---------ST--
FSILAVSERAIHAKHVQFVSGVHVATFWLSALLWDLISFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHEAD-ALAMLLVYGWAVVPLMYLLSFFFSGAAAAY------TRLT
VFNVLSG--------VATFLM---VTIMRIPAVKLEELS-RTLDWVFLVLPNHCLGMAIS
SFCE-------------NYETRR-YCTSSEVATH-------YCRKHXXXXXXXXXXXXXX
XXXXX--XXXXX---------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
-XXXX---X--XVEACGRAPVLPEDQDV-----ADERNRVLVPTLGLP-PHEPPLVIREL
SKVYELR--PPVLAVDRLSLMVQE

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSIRSELGKVRQ-RIGYCPQFDALLDHMTARETLVMYARL-RGVPERHIGACVENTLRG
LLLE-PHANKLVQTY---SGGNKRKLSTGIALI---------GDPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIIF--TSHSME----ECEALCT-----RLAIMAQGQFKCLGS
PQHLKSKFGSGCSLRAKVRA-------DGQK---AVLEEFKAFVQQT----F--------
-P-DSSL-----KHEYQRMIHYHIPSKDLTWRQ--VFGVLEKAKEKYGVDDYSVSQTSLE
HVLLSFAHLQPSAGDEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRSFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATHQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGIPQPWY-FFI------LPSY-WCGKPRAVAGKEE-EDSDPEKELR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKERAAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYVSGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHDHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEEHTAVKLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SVLLL--------
VVFKAFDVRAFTQDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIENNLLQRLRGILCAF-----
-RRRR---T--LTEFYTRMPVLPEDQDV-----ADERTRILAPSPDCL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-QIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSFC----TGWAMEEPGGQEILWHPQPWQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEDFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYSVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------GYIREGFLAVQHAVNKAIMRYHAPEAANNIFNKIT-LIV
KRFPYPAFFMDHFLEILQHMLPLLLVLAFTFTVLNIIRSIVLEKEKKLK-----------
----------------------------EYMLMMGLHNWLHWFSWFLVFFITFSIVIFFI
TILFHIKVK-NG----MAIFTKSNPVLI----------------------------FFFL
MCFAISSISFGFMISTFFNKA---NLAATTGGVLYFVIYIPYFLIEPQYSSLSYRQKLLS
CLLSNVAMALGILLIVNFEKK-GIGMQWKEFMSPINVNDNFTLGHVVLMLLYDSVFYG--
LVAWYIEAVFPGEYGMPQPWY-FFL------LPSY-WLKKPKMILKEK--EEEDLEKSPQ
HEFFESDPTDLQVGI-KIKN-LSKTF-KKGKKTKEAVRNLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTGLFPP-TSGQVYISGYEISQNMVHIRKNLGVCPQHNIFFDEITVAE
HLSFYAQLKGLPKKK-CQEEIDHILGILKMEPNRHAFSRTLSGGMKRKVSIGIALIAGSK
---V-VMLDEPTSGMDPISRRATWDLLQQQKSKRTIMLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKHK-YGAGYHLIIVKEPRCNIEEISH---LILNYVPTATME---SNVAAE
LSFILPKESSYKFE---S-LFTELEEKQTELGIASYGVSVTTMEEVFLR--IFKATFTYI
IHQKI--KQYVLLVHR-TFRDVNSKVDSSS-K-------------SGIM-GGMNSQS---
--RTIELEQLNVKLSGKRKTYFE-MGKESFVKIEFLKSENKNSMN-KTIHAPLSWLQV--
--GDLSALL---QRANCKPLILEKKKQDLTGITQHLKSISRTAPE------V----EKYL
NCQNKHQ-----K-TN------------------------------KELRKLKIKIIFIN
VLNNKKYNKIYRVTVVFSSFLMLLEAALVSVLINNHLKCSLLMKVSDTLLFLRLCPPLVP
RALAAYLPPSAPLLVKEIR-NAG-----GHKYRDWEFNVMVFSHHLILFFRELISLSTLS
FNKLHVLSRPSCQASFS----FPYFSFSSFGFIWRNL--------------L--------
LVSSGFEVCSFSVRAHFAFLLILRKTFWGHSLYPRVYSFSAHLLICCQGKIADTVTAQHE
LFSMLSL--------PTCLMLLL-VKYHSIPTRE---EK-QTLSL-ICVLPI---FVCFN
SQIPRLIFIKKNSLRPTYQEALK-FCAEFFKKLELFQ----------------VYQYSKE
WMAVYLYIAILY---------------SRSHCYICKGTCI--YINCKGPDS-CQ----VS
VPGQQ---EALSINIMKKLSELEGDNNYTAALGEGNRNNL------RDCGFDFPSILSTK
SQVYGRR--VRLLAVNRISLTVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGDETITSGTAYID
GYNIITHIKKVQQ-RIGYCPQFDALLDYMTGHETLVMYARL-HGIPEHHINSLVKDMLQG
LLLE-VHSDKLIKTY---SGGNKRKLSAGIALI---------GEPSVVFLDEPSTGMDPV
ARRLLWDAITRSRESGKAIVI--TSHSME----ECEALCT-----RLSIMVKGQLKCIGS
PQYLKNKFGSGYTLLAKIKS-------SNEK---DNMTIFKKFIEET----F--------
-P-GSIL-----EDEHQGIVHYHLPFRDLNWAK--VFGILEKNKDQYELDDYSISQISLE
QIFMNFFRIQQLSEEEG-------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLFG
YKKLMILLWKNFTL---KRRKLVALVV

PF12698 // ENSGT00760000118965_2_Domain_0 (88, 665)

EIILTILFGIILLAIRKFII-IKKT--------
----------------------GPFSYNA--HPINDLPSFIRSPV--TVS--YPWELAYV
PSK--SIVVQNIVENVKRDL-------NTNLKVIGFSSER-------AFEDYVEQTNN-S
KNVLAAIVFDHVFQSTNDPLPLKVKYYLRFSSLKK-NNKF----GDSFEASSWLTNSLFP
SV-PPVGPRNQQEE--DGGSPGYISEGFLLVQHALDKAIMLHHSGTAAEKLFNGVR-IFV
QRFPYPMQYQDFFYVFAGIFIPLVTICIFSLNHLILIQSIVWEKENQLK-----------
----------------------------EYQLMIGVSNWMIWAAYFFIFLCLYFLTIIYM
CIILFFKIE-P-----APIFQYSDPVLV----------------------------FIFL
LFYAISLIFYSFMISTFFNKV---NFAVALGGFLFFITYLPATRLLVNAGQMTLKQKLIF
CLSCNVAMALGFKFLLDAESN-KTGIKWSNIFSSANL-DNFLFAYVLGMFLFDTFLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGQYGVPKPWN-FFL------KHSY-WFGEPPKK--QL--EPIQHHETIE
NKYFEAEPTDLVAGI-QIKH-LHKVF-KVNHAIKVAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQITVLLGH-N
GAGKST--TLSILSGLYPS-TSGEAYVYGYEISQHMTEIRKFLGLCPQQNLLYNYLTVSE
HLYFYCVIKGVPQNL-RHQEIDNMLSAFNLLEKRDAFSKSLSGGMKRKLSIIVALIGNSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1285)

SGMDPASRKATWDLLRTYKQDRTILLTTHYMDEADVLGDRIAIMATGS
LQCCGSSIFLKHL-YGVGYHIVMVKEPHCSVEGISE---LIHDHAPTATLE---SNAGTE
LSFVLPKEFTHRFE---A-LFTALEERQTELGIASFGISVTTMEEVFLK--VGHMEVSES
HIQAK--Q--SFPQKS-KISIMSQNKNISSNV------------------ERAH------
--SSTLNE--IIMFNTGISLYCQ-QFHAMFMKKLIFSWRNWKITL-IQILGLVVSTFVFF
QSNYLV-------HHDEMARKMDLDQYGQTIV---PFYISGSSN-------LTTSLLEHL
ESMLKSKNHKLKE-VS-----GNL

PF12698 // ENSGT00760000118965_2_Domain_2 (1285, 1718)

LDYL-----MENKECNRLCIIAFSVEVKTDETVFTV
FFNNEAYHSP-----------------------------SLSLAVLDNILFMSLSGANAS
LTVFNKPQPRLDNKVI-----EG-----TINGQEVFLDMQLGIALLI---------SS--
FSLLTVTERISKAKHIQFVSGVSVIVYWFSALVCDFIIFLFS-----CFLLL--------
GLFKYCKVDIYVMDYHLLE-TMLILTLYGWSAIPLMYLMSFLFSRSSSAY------IKLI
LFNFVSG--------TFTVFID--GILRDGTSTNLSNGTRKFIRNSFLLFPNYNLGKCIS
DYTV-------------IYHMKI-LCTQKKN-IHKFLN----CSKE--NTEKNIYSLEEH
TIGKH--LIIMS---------------IAGCLFILFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFCDNTL-WKLRTFLNKHVYFA-
IYKKYKKG---IISKE--LSGESPDKDV-----EDERKRILEHSK---ELMNSPVLIKEL
TKIYFTY--PVILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLEVQRQE-CFGLLGYNGAGKTSTFQILTGEQSPTSGDVFID
GFSITKNILKVKS-RIGYCPQFDALLEYMSGREIMIMYARI-WGVSEHQIHLYVNKHLSS
LELE-PHADNIIRTY---SGGNKRRLSTAIAIM---------GKSSVIFLDEPSTGMDPV
ARHLLWNTVTKTRESGKAIII--TSHSME----ECDALCT-----KIAIMVKGKLMCLGS
PQHLKNKFGDIHILKVKVKT-------E------DKLEDFKYFIKMT----F--------
-P-DSIL-----KEENQRILNYHLPKKDNSWGK--VFGVLEKAKDRFNLEDYSISQITLE
QVFLAFANPVSGLTAGDDEEQ-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATRQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFI------LPSY-WCGKPRAVAGKEE-EDSDPEKELR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------SLCGAM-DPSDGIGAL-
----IEEEHTAVKLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIENNLLQRLRGILCAF-----
-RRRW---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVHS-------EGQQ---EALEDFKAFVDLT----F--------
-P-GSIL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYSVDDYS-------
------VSQ----ISLEHVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VLGFSTEE-------EFEDYVKEVNN-S
ERVMAAIVFDHDFKNSNDPLPLKVKYYLRFSNEKK-SNML----ENIYEEASWLTDFLFP
PI-PSVGPRNQD-E--DGGSPGYISEGFLFVQHSLDKAIMQYHSGQAAEMLFSSIS-VDV
QRFPYPSYYHDFFFMFSGVFIPLVLVCIFSLNHLTLVQSLVWEKEHRLK-----------
----------------------------EYQLMIGVSNWMLWVAYFFTFLCLYSIIIIFM
CIVFFVKVK-P-----APVIQSSDPTLI----------------------------VIFL
LFYAIATICFSFMVSTFFSKV---NIAVALGGLFFFAIYFPAAGLHVYYGNMTFIQKLAA
CLSSNFAMALGVKFLADAETW-RVGLKWSNIFSSTTL-DNFYFAHVLGMFLFDAFLYS--
LVAWYIEAVFPGSYGVPKPWN-FFL------QPRW-KMVQGLLI--NL--KI-ELSYDPA
IPLLDMYPKEIICGA-KIIHFVKVVF-QTHNTTKVAVNDLSLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

ST--TLSILSGLYPP-TSGNAYINGYSISKQMVQIRKSLGLCPQQNLLFNYLTVSE
HLHFYSVIKGVHGKM-TPTEIDRMLTTFNLLEKRNKLSKSLSGGMKRKLSIIIALIGGSK
---V-VILDEPTSGMDPVSRRVTWDLLQHFKLDRTILLTTHYMDEADVLGDRIAIMVKGS
VRCCGSSIFLKKI-YGVGYRIVMVKTPDCNVEEVSK---LIHYYIPTATLE---NDVGTE
LSFILPKNYAHSFE---A-LFTALEQEQENLGISSVGASVTTMEEVFFK--VGYTEESQT
DIETL--K--SSSQMG-QASNRNQNKNMSRNV------------------EGAD------
--PPTLNESPTINFNTGCSLYSQ-QFCAMFVKRVMFNWRNWKLLL-LQILGLIGSLAFLL
SSSKNS-------SQHEMIRQMELSQYGQTIV---PFSISGASN-------LTADLSERL
KSMLESDNQRPQE-VQ-----GDLLKYL-----RETKDCIRLCIIALSIESEANMVMLTA
LFNNEAYHSP-----------------------------SVALAVLDNILFKSLSGANAS
LTVSNKPQPLPDIEDN----EDR-----LQSGQKLAINLQFGMALLI---------NG--
FCLLTVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
GVIKYRKLDIYVTDYHILE-TMLIFTLYGWSAIPFVYLISFVFSGSTSAY------IKLL
LLSYFSG--------TFGFLIATWMQLEAITLS---KLTQRRFEHTSLLFPNYNLAKCVS
QYTT-------------IYDVKI-LCTTLKK-HPVYLN----CSKEISDTEKNIYSLEEP
MIGKY--LIDMS---------------TAGFIFLVLIFFWETTS-WRLRTFLNQYIYFG-
IYKRYRTT---LRELKIRSERQSEDEDV-----QNERKRILEQSQ---ELLDSIVLIKEL
IKIYFKC--PAILAVKNISLAIQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAHEIMIMYARI-WGVSETQIKLYVNKWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSVIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLEDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDEN----------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------GINMRVHGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYLWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATRQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLVFFLFLLIASSFM
TLLFCVKVK-SD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWQDLLSPVNVDDDFCFGQVLGMLLLDSMLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFI------MPSY-WCGKPRTVTGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-MVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDSLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHTLGLEDKWNSPSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKRDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPTDGIGAL-
----IEEERTAVTLNSGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPVTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSIPGTSR-------LGQQLSEHL
KNSLQAEEQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTV-TA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGSHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------TSGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLQRLRGILCVF-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSSDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHSISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGQNLSWAK--VFGILEKAKEKYSVDDYSVSQISLE
QVFLSFAHLQPSATEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRSFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHANAATHQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFI------LPSY-WCGKPRAVAGKEE-EDSDPEKELR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEEHTAVKLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTQDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIENNLLQRLRGILCAF-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDCL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEDFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYSVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNQLT
VNQLTVLLWKNFTL---KKRQIISTSAELLAALLFVIMLLIFRALTD-MNIA--------
----------------------GPYHFTP--QPIAIMPSFIKDA--------QEWELVYI
PSE--IDVVREIIEDVKRNL-------NTTIKVRGFPSEA-------EFEEYILFDNM-S
QKVLAAIVFDCGFKNKSDPLPLQVKYHLRFVGAQRTIW--------WPDKLGWKTRLLFP
NH-PSIRPRNPNYL--DGGSPGYIKEGFL

PF12698 // ENSGT00760000118965_2_Domain_0 (330, 665)

AVQHALDKSIMLYHESSAGKKLFDEID-TVI
QRFPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIMGLRNWIIWIGYFFTFFPLYVIVILLI
CILLFI----VE----EPILRYSDCSFI----------------------------FVFL
TCYAIASICFAFMVSTFFSKT---RLAASAGNLLFFASFFPYNFISEYYGMLNLTTKITA
CLSANVALALGINILIKLEIQ-EIGVKWHNLWTPANLEDNLNYGYMLGMLLFDAFLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YVEAVFPGQCGVPQPWY-FFL------MRSY-WFGKPKIKKT-T--E-EAKCTPIV
HNCYEAEPPNLEAGI-HIMH-LH-----KEFKNKPA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNLSLNIYE---GQVTVLLGH-N
GAGKTT--TLSVLTGVYPYASRVKAYINGYNISDNMIEVRKDLGFCPQHDLLFDDLTLSE
HLFFYCMVKGIPQNI-NCEEIDRMLSAFNLQENYHTLSGSVSGGVRRKLSIVLALMAGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1181)

SSGMDPVSRRVTWDILQHYKHNRTILLTTHYMDEADVLGDRVAIMVRGT
LHCCGSSVFLKQI-YGAGYHIVMEKQQYCDVDNIIA---MIQQHVPGAVLE---NNIENE
LSFILPKKYVSRFE---T-LFTELEMRQKALGIASFGASITTMEEVFVK--VNKLATPQK
SIQTI--QPYYLAYRK-MRQDEQQNVNMPINY------------------SKPN------
--FPYLSEIATVKFNTGVPLYRQ-QFYSLFIKRALFISRN

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKFML-LQIIVVMVVTTYLL
LALHLN-------NNDIPERELNLSHYGRTIV---PYSTSGNSD-------LALNLTKNL
NIFLKSKNQNLRK-IR-----GDMNDYI-----LKNKDCHTFCLVALSIKVERDKTVLTI
FFNNEAYHSP-----------------------------AISLSILDNILFMTLSGPDAS
ITVFNKPQPL--PHYGSNI---V-----PVNGLQIVQCLAFGISVVV---------GS--
FSIQTVTERTNQAKHIQFLTGVCVHTYWLSALLCDLIFFFFA-----CCVLL--------
AIFKFCQLEAFVVHYNFLD-TILIFMLYGWCVVPLTYIASFLFNSSTAAY------IKIT
LFNYFST--------MFSIIIYTIIQFYG---NDFPNFVHILIRAILMALPSYNLAMSIS
KYFD-------------DYEVKR-LCAREF--KSIYVD----CSDP--YTQNNVYGFGEH
GIGKF--LITLA---------------TMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1815)

LLSLESVS-CSLKSFVFRNIIFY-
FYNKLRKGRNAIPSNQ--RTKEDEDEDI-----KKEKGKVFTLL---LRLQNTPLLLNEV
TKIYFKC--PVVKA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGIAFID
GNSVTRTPRKIRS-RIGYCPQTESVLNHMTGRESLVMYARL-WGVLEQDINEYVEAFLHS
VHLE-PIADQFIHTY---SAGSKRRLSTAIALM---------GKSSVVFLDEPSIGMDPV
AQHLLWETITWICKTGKAIII--TSHRME----ECEALCT-----RLAIMVKGRFTCLGT
PQHVRKRFGHVYTLTVRINI-------AKDE---DKVEEFKNFIKVT----F--------
-P-GNIK-----FQEFHGTIGYYIPSKEIYWGK--VFAILEEAKVLFKLEDYSVKRVTLE
QIFLTFANTDKMRTYQEIKLQ---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MTL
GRNLKLLLWKNFIL---KKRKPLVTM

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LEVLAPLLFSMIIMYLRLNSV-PRER--------
----------------------PPMSYLA--LNVSLLPDFL-RLA---AQ--STYQLVYV
PSQ--SDTLKAVTEAVAKAF-------EVEFEVLGYPSVP-------LFENYVIQDPR-A
FYVLAGIVLDHSFNDRQQPLPLEIKYRLRFSCIQRNSLTSK-LTSYYDTLEGWGTSLLYP
RN-PSQAPRAFGQI--DGGLPGYNQEGFLAIQHALDKAIMQHHAHNATTRMFEDLT-VLV
KRFPHGAHIQDKFLLILQNEFPLLLMLSFICIELIIINSIALEKERKMK-----------
----------------------------EYMCMMGVNNWQHWAAWFIMFFISTLIVISFM
TILFCIEVH-G-----VVVFRNSDPSLI----------------------------FVFL
LCFATATILFAFMISTFFQKA---HVATAAGGIIFFFTYLPYLYLTFSYPQRTYFQKVAF
CLLSNIAMALGVRLISSFEIR-GTGMRWKHVG---GLSGEFNFSHVLVMLVLDSVLYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVLPGEYGIPKPWY-FFV------MPSH-WQGRSSSLTRSV-LDVGDPDKASE
SKFIQEEPTDLAKGI-EIRQ-LYKVY-QTGKSKHVAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KGLTMNLYQ---GQITVLLGH-N
GAGKTT--MCCMLTGVLAP-SSGWVYINGYDISCNVAQIRKSMGWCPQHDILFDNFTVAE
HLYFYARLKGLSCHK-CPEEVQRMLHVLGLEDKRDALSKFLSGGTKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1185)

SGMDAISRRAIWDLLQQHKSDRTVLLTTHFMDEADLLGDRVAIMAKGE
LQCCGSSLFLKQK-YGAGYYMTLVKKPHCSTEKISH---LIYQHIPNAVLQ---SSTGEE
LTFILPKKNIHRFA---R-LFTELERRQVELGVASFGVAVTTMEEVFVR--VNKLSDTST
DIQAL--KTSSMQSQL-------------RIPISR-------IK--RFHSRI--------
--FSLR-SGLPIHMNTGLSLICQ-QFYAMLLKKITYSWRNWMMM

PF12698 // ENSGT00760000118965_2_Domain_2 (1185, 1718)

LTVQVLVPLAITVFSL
AFLNLET-R---L--DDVPLELTLKTYGQTIV---PFYISPNSR-------LNPQLLEYF
TDMLVAEEQIPLE-TP-----TLVEDLLLKRAEEEPESFDNRYIVAASFEDSGNHTTVTA
LFNNQAYHSP-----------------------------AVALALVDNVLFKLLSGTRAS
ITAVNHPQPQSAVEALEDI-LYQ-----GPKGHYLVIHLLFGIAFLS---------SS--
FSILTVKERATRAKHIQLTSGVYVTTFWLSALLWDLITSLVP-----SLLLL--------
VVFLHYKEEAFTHKDNIPA-VILVLMLYSWASIPFIYLTSFCFQYEGSAF------IKLI
IILTFLS--------IGPF--IL-VSVTSEKELGYTTVS-DSLDHTFLLLPGHCLGMALF
NLYY-------------NHGMQK-LCKIKNLSQYECNEI-----SEGFTVQESIYAWESL
GMGKY--LTALA---------------ILGSVYLIFL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNILRELKAR-FST-CNK-
----K---RE-LV-TSPDAPSKPLEQDV-----GQEATTVATYLKKLR--QENPLVLHEV
SKVY-AT-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFTVQAGE-CFGLLGLNGAGKTSIFKMLTGDEPITSGDAFLR
GLSIRSHIREVGL-WISWCTEIRSISEFVQYKQTEDLSAEI-QGLPETSIKPSPDLVLSR
EHTC-AYSLERKPTY---GGGNKRKLSTGIALL---------GEPSVIFLDEPSTGMDPM
ARRLLWSIISRARESGKAIVI--TSHSME----ECEALCT-----RLAIMVEGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DKQQ---EALEEFKAFVNLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGADLSWAR--VFGILEQAKTKFMLDDYSVNQVSLE
DIFLSFTGSMPVTKEENKHK---PAEDSSTSPPPSSSQLPSQPPSPPASQPPFQPPSPLV
SPFLPP------YPPPSQPPS----PPASQ---PPSSSQLPSQPPSP---PASPPLSQPP
SPPASQ---------------------------------------

-------------------------------------------------------MAWLE
FRAFRSLLWKNFIL---KKRRIINLLTEIFLTIVFGVGILLARKFVV-VKKN--------
----------------------GPFNYSA--QQVDNVPTFIGAPA--TTP--YPWELAYV
PSK--STAVQNIVENVKDNL-------NSNMKVLGFSSER-------EFEDYVKQNNK-T
KNVLAGIVFDHDFQNSNDPLPLKVKYHLRFSSFKKNSRKF----ATQLEEESWLTNSLFP
SM-PSMGPRNQHDA--LGGNPGYISEGFLAVQHALDKAIMRHHNNTATETLFNGVK-IFV
QRFPYPSYYHDVFFLFAIVFIPLIIVCIFSMNHLTIIQSIVWEKENRLK-----------
----------------------------EYQLMIGLSNWMLWTAYFFTFILLYFIIIIII
CIILYIKIQ-S-----VSVLEYSDPIIV----------------------------FIFL
LFYTMPSICFSFMVSTFFSNA---YFAITLGGFCFFITYLPAANLSVNYGQMTFNQKIVS
CLSSNYAMALGFKFIFDAEVK-KTGIKWNNIFSPNKQ-DNFLFAYILGMLLLDALLYF--
IVTWYVEAVYPGKYGVPKPWN-FFL------QPSY-WFGEPPVK--KS--ETHQFQETIQ
SKYFEAEPTDLVTGI-TIKH-LHKVF-QDKGTTKVAIKELSLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

ST--TMSILSGLYPP-TSGEAYVYGYDISTQMVQIRKSLGLCPQQDLLFNYLTVSE
HLQFYSAIKGIPQKK-CLKEIDHMLSAFNLLEKRDAFSKSLSGGMKRKLSIIIALLGDSK
---V-VILDEPTSGMDPASRRATWDLLQNYKQNRTMLLTTHYMDEADVLGDRIAIMVQGY
LQCCGSSIFLKKL-YGVGYHIVMVKEPHCNVEEVTK---LIHYYAPAATME---SNVGTE
LSFTLPKEYAHRFE---T-LFTALEKRQEKLGIASFGASITTMEEVFLR--VSHMENVPE
DILAM--Q--PPSQMS-QPTMN-QNR-NASDV------------------QGVH------
--SPTLNES-SIRFNTGCSLYCQ-QFRAMFLKRIMFSWRNWKLVL-VQVLGLAASFAFLF
EVANPS-------NAEEKARKMDLGEYGQTIV---PYSISGNSD-------LTTNFLKLL
ESKLISEKQKLKE-VK-----GDLLNFL-----MENSD-NRLYIIALSIEVKTNETVFTV
LFNNEAYHSP-----------------------------SVALAVLDNVLSMSVSGKDAS
LTVSNKPQPRPNSKDK-----ER-----TENGNMVASNIQLGVAILI---------SG--
FCLLTVTEKTSKAKHIQFLSGTSVFVYWISALLCDFIIFFIS-----FLLLM--------
IVFRYYKLNIYIMEYHILE-TMLIFTLFGWSAIPLTYLLSFLFSGSTSAY------VKLI
LFNYFSG--------TICILIDNSV----DIMRSLSNGTKQFLRNLLLLFPNYNLAKCLS
EYTN-------------IYSLKI-LCNALKT-PSAYLN----CSKE--NTKKTIYSLEKG
MLGKY--FIIMG---------------IAGFLFLLFILLWESTF-WRVRTFLNQQVFFR-
IYKKFKKE---QVSKK--LSGKSEDEDV-----QNERINILQHPE---KFQNSVVLIKEL
TKIYFKY--PVILAVKNISLAIQKKE-CFGLLGFNGAGKT

PF00005 // ENSGT00760000118965_2_Domain_3 (1841, 1974)

STFQILTGEESATSGDVFID
GFSINRNVLQVRS-RIGYCPQFDALLEYMTAREILIMYARV-WGVSESQIQLYVNSYLNS
MELE-PHANKIISTY---SGGNKRRLSTAIALM---------GRSSVVFLDEPSTGMDPV
ARRLLWNVVTKTRDSGKAIVI--TSHSME----ECDALCT-----RLAIMVKGKFMCLGS
PQHLKNKFGNIYILKVKGKS-------E------HMLEPFKNFIKMT----F--------
-Q-GSDL-----KHQNQKILNYYIPCKDNGWGK--MFGILEKAKEQFDLEDYSISQITLE
QVFLTFANPENTD--DDSLQK-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASLE
TKKLVILLWKNLTL---KRRKFGALVTEIVLMFVFSVVLLATRKLLP-IKKI--------
----------------------ESVR

PF12698 // ENSGT00760000118965_2_Domain_0 (147, 665)

YPH--RPVSGVPSFIYVFT---SS--HPWELAYV
PSN--STMVQNIIENVKKDL-------NFRMKVTGFSSES-------DLEDYIRSAVN-S
RNVLAAIVFDHSFTNSNDPLPKKVKYYLRFSNVKKNVN-A----GAYFQERSWFTNFLFP
PV-RLLGPRNRYDE--DGGSPGYISEGFLAVQHALDKAIMLHHGSAGATALFNNTS-LLI
QRFPYPAYRDDYFHTFANIFIPLILACTFFMNYLTLVRSIVWEKENQLK-----------
----------------------------EYQLMIGLGSWMLWVAYFFTFFCLYVINITFI
CMVLFVKTE-P-----APIFQYNDPILV----------------------------FVFL
SFYAISSIFFSFMISTLFNRV---NFAVTLGSCFFFLTYFPCITMYSNYEHMTFKQKLIW
CFNFNAGMMFGLKFLIDAETR-KTGMKWSNIFSPADT-DSFLFAYVLGMLLVDAFLYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YTEAVFPGEFGVPKPWN-FFM------TRSY-WFGETPKM--KP--EITQLHEIIQ
SKYFEAEPVDLMAGI-QIKH-LHKVF-QEGNTTKIAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLTLNLYK---GQITVLLGH-N
GAGKST--TLSILSGLYPP-TSGEASIQGYDISQHMAQIRTSLGLCPQQNLLFDHLTVSE
HLYFYCGVKGIPQKM-CLEETSNMLTAFNLLEKRDTFSKSLSGGMKRKLAIIIALMGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1268)

SGMDPASRRTTWDLLQAYKQDRTILLTTHYMDEADVLGDRIAIMVQGT
LRCCGSSVFLKRL-YGVGYHIVMVKEPHCDIDEISK---LIHYYASAATLE---TNVGNE
LSFILPQEYTHRFE---A-LFTALEENQENLGISSFGVSITTMEEVFLR--VSHMEDSKP
DIQAT--QSPS--VGS-KE---SKNKDVPS-N------------------IRGG------
--FPTQSEDPTIVFNTGCPLYCQ-QFHAMFIKRLLHSWRNWRVLL-VQTLGFVISTLFLL
KSGDLS-------YEDEKTRQMNLDEYGQTIV---PFSISGKSN-------LTTSLLTHL
EKMLKPG

PF12698 // ENSGT00760000118965_2_Domain_2 (1268, 1718)

NHKIKE-VQ-----GDLLKYL-----EGNEECIHLCIVALSIKVVANRTELTV
LFNNEAYHSP-----------------------------SLSLAVVDNILFMSLSGVDAS
ITVFNKPQPHPQAKDS----LG------SAEGKVVALKIQLGMALLV---------SG--
FCFLTVTERTTKAKHMQFLSGVSVLVYWISALVFDLIVFFIS-----CCLLL--------
VVFKYCKADIYVTDYHILE-TLLILTLFGWSAIPLTYLMSFLFSKSTSAY------IKLI
MFNYVSG--------ILSILIDT--IIAAKIPLTLSNTTKTVLLSSLLFFPTYNLGKCIG
DYTV-------------IYQRKI-QCTQRQN-VPKYLN----CSRE--NTEKNIYSLKEH
MIGKY--LIAMT---------------VTGLVFLLFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

LFWENIF-WKLRTFIHQHIYFG-
FFKKYKTD---RISKE--LSGESEDKDV-----ENERRKILYQPE---KLLNSPVLIKEL
TKIYFKC--PLTLA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIKERE-CFGLLGFNGAGKTTTFQILTGERTPTTGDVFVD
GISITKNILKVRS-KIGYCPQFDALLEFMTGREIMVMYARI-WGVPEHQIQSHVGEHLNV
LDLE-PHANYVISTY---SGGNKRRLSTAIATM---------GKPSVILLDEPSTGMDPK
ARRLLWDTVIKIRESGKAVII--TSHSVE----ECEALCT-----RLSIMVKGKLTCLGS
PQYLKNKFGNIYILKAKVKS-------V------ETLKDFKNHITLT----F--------
-P-GIDL-----KQENQGILHYYIPSKDNGWGK--MFGTLEKAKEQFNLEDYSISQITLD
QVFLAFANQDRK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------NG--
FCLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1445, 1581)

TVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
VSYFCLH--------------------------------------QTSPY------S---
---ATFR--------HFGFL

ENSGT00760000118965_2_Linker_2_3 (1581, 1815)

IEIVGQVVEEKLTNISNTTRTVVRNSLLLFPNYNLAKCVS
QYTT-------------IYDVKI-LCTTLKK-HPVHLN----CSKA--NTEKNIYSLKEP
MIGKY--LIDMS---------------TAGFIFLVLIFFWETTS-WRLRTFLNQYIYFG-
IYKRYRKE---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLDSIVLVKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIKLYVNKWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSIIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLQDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QSIQELPLFFSFPP---PG--DTWELAYI
PSH--SDSARTITETVRKAL-------VINMRVHGFSSEK-------DFEDYIRHDNH-S
SNVLAAVVFEHTFNHSKDRLPLVVKYHLRFSYTRRNYMWTQTGNIFIKETEGWHTNSLYP
LF-PSPGPREPSSP--DGGEPGYIHEGFLAVQHAVDRAIMYYHANTSAHQLFQKLM-VVT
KRFPFPPFISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVLEKEKKL------------
---------------------------KEYMHMMGLSGWLHWSAWFLMFFLFLLIVVSFM
TLLFCVKVK-KD----IAVLSSSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYFFTYIPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSVLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVLGKEE-EDSDPEKALR
AEYFEAEPEDLVAGI-KIKH-LSKVF-RVRNKDKMGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGHAYIHGYEISQDMIQIRKNLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQMLHILSLEDKRDSRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAMSRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKKK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDP---------------NLCGVM-DPTDGIGAL-
----IEEEQAMGKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKMVA-AQVLVPLTCITLAL
LAINYSSEV-----FDNPLLKLSLCNYGRTVV---PFSVSGTSQ-------LDQQLSEHL
RDMLQAEGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDKGEKTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSALQVAKDQ-FSE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFRAFDVHAFTRDGHMAD-MLLLLMLYGWAIIPLMYLMSFFFSAASTAY------TRLT
IFNILSG--------IATFIM---VTIMRIPAVKLEELS-RTLDHGFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSKVATH-------YCKKYNIQYQDNFYAWSTP
GVGRF--VTSMA---------------SSGCIYLTL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFLIETNLLWRLRTFICAF-----
-RRRW---T--LAELQNRTSVLPEDQDV-----ADERSRVLAPSLDSM--LDVPLLINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSIGSDIRKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLISAYVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGQQ---EVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLSGHDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPATEEG-------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTLLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATLYPS--QSIRELPLFFSFPP---PG--ATWELAYI
PSQ--SEAVRTVVESVQRAL-------VINLRARGFTSEK-------DFEDYIRYDNR-S
TNVLAALVFEHTFNHSRDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMHHHANASAHQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLSIIRAIVQEKEKKL------------
---------------------------KEYMRMMGLSSWLLWTAWFLLFFLLLLVAVSFM
TLLFCVKVK-KD----VAVLAHSDPTLV----------------------------LVFL
ACFAVSSISFSFMVSTFFSKA---NMAAAIGGFLYFFSYIPYFFVAPRYNWMTLSQKLFS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFTFGQVLGMLLLDSVLYG--
LVAWYVEAVLPGQFGVPQPWY-FFI------LPSY-WCGRPRTALGKEE-EDDDPEKVLR
TEYFEAEPEDLVAGI-KIKH-VSKVF-RVGNKGKAAVRDLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGRAYISGYEVSQDMDQIRKSLGLCPQHDVLFDDLTVAE
HLYFYAQLKGLPRQK-CPEEVKRMLHVLGLEEKRDSRSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPTSGVDAISRRAIWDLLQQHKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKEK-YGAGYHMTLVKEPHCNPEGISR---LVQHHVPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDG---------------HLCGTM-DPTDGVGAL-
----IEEECTAVRLNTGLALHCQ-QFWAMFLKKATYSWREWKVAA-AQVLVPVTCLTLAL
LAINYSSEI-----FDDPLLKLTLGEYGHTVV---PFSVPGTSR-------LDQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDTGERTVITA
LFNNQAYHSP-----------------------------ATVLAVVDNLLFKLLCGPRAS
ITVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAIQAKHVQFVSGVHVAIFWLSALLWDLLSFLIP-----SLLLL--------
VVFKAFDVHAFTRDGHVAD-ALLLLTLYGWAIIPLMYLMSFFFSGAATAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDRVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSDVAAH-------YCRKYNIQYQENFYAWSTP
GVGRF--VTSMA---------------ASGFAYLTLLFLVEADLLWRLKTCLCAF-----
-QRRR---A--LTEVYTRTAALPEDQDV-----MDERNRILSPSLDSL--LDTPLIIKEL
SKVYEQR--APLLAVDKVSLAVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RIGYCPQFDALLDHMTGRETLVMFARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRMY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVGLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDDLSWAK--VFGVLEKATEKYGVDDYSVSQTSLE
QVFLSFAHVQPPTEDAGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------NG--
FCLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1445, 1616)

TVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
GVIKYRKLDIYVTDYHILE-TMLIFTLYGWSAIPFVYLISFVFSGSTSAY------IKLL
LLSYFSG--------TFGFLIG--EIIENKKLTNISNTTKTVVRNSLLLFPNYNL

ENSGT00760000118965_2_Linker_2_3 (1616, 1815)

AKCVS
QYTT-------------IYDVKI-LCTTLKK-HPVHLN----CSKA--SKYLRVPKSSKL
ASGSF--IVLFN---------------SRTYIWFLF---------------NNLVSASI-
IFVLKIQE---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ESLDSIVLIKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIKLYVNEWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSVIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLEDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLL
MRQFLVLLWKNFLL---KSRKVFGLVVEIILIFLLFVWTLTVRRISK-KKFI--------
----------------------PAMIFNP--IPLT-LPGFLN------QN--FDYELAYV
PSD--SNAARNITEMVKKDL-------NFNFKVQGFSSEE-------SFE-YIKYEDK-G
HSLFASVVSRSWFSTSVSKVRLKVKYSLRFGRMYDPENVLK--PSERQKETEWNTSILFP
SV-PSLGPRNVLEN--DGGNPGYIREGFLLVQHSVDKAIMMHHSGRAAEAMFANTT-IYA
RRFPYPAFIHD

PF12698 // ENSGT00760000118965_2_Domain_0 (372, 663)

NFLWTFIVMFPWTILFTFTQMALDIIGTIMLEKEKRLK-----------
----------------------------EYQLMVGLSNAMLWVSYFITFLLMYFIIICLL
CGILFLKIT-H-----ERVFQHSDPLFI----------------------------AFYF
LCFAISSMLLGFMISTFFNRA---SLATSIAGFLHFLTFFPYLIVFSLYDQTSLSGKLAL
CLITNTALAFGTDLICKLEMK-GHGAQWYNFATKVNPDDDLTLAHIIGMFLFSAFLYG--
LV

ENSGT00760000118965_2_Linker_0_1 (663, 758)

AWYVDAVFPGKYGVPKPWN-FFL------QKTY-WFGEPALS--R---EESQVSDLPP
SDFMEPEPVDLEAGI-QIQH-LYKEF-TLKNSTLMAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSILTGLYLP-TKGKVYISGYDISSDMVQVRKSLGLCPQDDLLFPLLTVSE
HLYFYCVIKGISSTN-RPREIHRMLTSFGLLQKSNTMSKDLSGGMKRKLSIIIALIGDTK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1190)

SGMDPVSRRAIWDLLQHYKKDRTILLTTHHMDEADVLGDRIAILVMGV
LKCCGSSLFLKKL-YGVGYHLVIVKTPDSDDGKISQ---LIKNYIPTAEME---TNVAAE
LSFILPKEHTHRFA---E-LFTDLEERQEELGISGFGVSMTTMDEVFFK--VSNLADLKL
NTEIA--QSASTVNP--STSENNENMNVPRNF------------------ERS-------
--GY-SGRYSDSSFNAGWPLYMQ-QFRAMFIKRVMFSWRNWKLLL-LQL

PF12698 // ENSGT00760000118965_2_Domain_2 (1190, 1718)

LALQGLTYVLI
KGIGFS------V-PKEPARVMDLEQYGETTV---PFSVSGDPP-------LTQKLTKNL
EIMLKDKKQKVHE-VQ-----GGVQDYL-----LTNKDCIYSCIVAFSLDVTRKEKTFTF
WFNNEAYHAS-----------------------------PLSLSILDNIIFKYLSGPDAT
ITVSNKPQPQPFTKGRS---EER-----SASGIQIVFNLLFGMSIFT---------SG--
FCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIIHFVA-----CVLLL--------
LVFLYTDVHILLENYNFLD-TMLILMLFGWSIIPFIYLLSFWYNNSTNAY------IKIF
VFNHCLG--------FMSIIVDAVVELI----PDIKTSTKNLILNSLLLLPIYNFGMSIF
KYYS-------------IQEIRK-LCSSLGS-LNTFSG----CQHE--PYSVTVYSMDKR
AIGRH--VTAMA---------------ATGLIYFLFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

ILLETTS-WNLKAFIYRYVLFG-
IYKIFYKA---RMSKE--LSGDSEDEDV-----QNERETILQHSW---HSLNSTVLIKKL
IKIYFKI--PPTLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLTIQKEE-CFGLLGLNGAGKTTTFKILTGEEIATSGDVFIE
GYSITRNILKVRS-KIGYCPQFDALLDYMTSREILTMYARV-WGIPENNIRSYVNNLLKM
LYLK-PQAEKFIYTL---SGGNKRRLSTAIAIM---------GNSSVVFLDEPSTGMDPL
ARRMLWNAVIRTRESGKVIII--TSHSME----ECEALCT-----RLAIMVQGKLVCLGS
PQHLKNKFGNIYTMNIKFKT-------GTDD---DVVQDLKNYIAEV----F--------
-P-GSDL-----KQENQGILNYYIPSKDNSWGK--VFGILEKAKEDYNLEDYSISQITLE
QVFLTFANPDNTESGYEKAVP---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
FRQFTLLLWKNYTL---KKRKIVVTVLEILLPLLFSGILIWLRQNIRSENIP--------
----------------------NATIYPG--QPISDLPLFFNFPP---PE--DTWELVYV
PSN--NEAVKTITEMVKKTL-------VIDMKVRGLPSEK-------DFEDYIKFNNH-S
YNVLAGIVFEHNFNHYKEPLPLEVKYHLRFSYFRKNDMWAGMTLFFPKEIEGWHTTSLFP
LF-PNPGPREPSFP--DGGEPGYIQEGFLAVQHAVDKAIMQYHASAATTRLFEKVT-IIA
KRFPYPPFISDSFLIAIQYQLPLLLMLSFTYSTLTITRAIVQEKERKL------------
---------------------------KEYMRIMGLSNWLHWSAWFLTFFLLLLFTVFFM
TVLFCVKIE-ED----IAVITNSDPSLV----------------------------FVFL
TCFAISSISFSFMVSTFFNKA---NLAAAIGGFLYFFTYIPYFFIGPRYNWMTLNQKLSS
CLFSNVAMALGAQLIGKFEAK-GMGIQWKYLMKSVNVDDNFTFGHVLIMLLFDSAFYG--
LVTWYVEAVFPGEYGMPQPWY-FFL------MPSY-WCGNQRSMMGKEE-EEDDPEKVLK
TEYIEAEPEDLVAGI-KIKH-LSKMF-MVRNKRKEAIRDLTLNMYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTGLFPP-TSGRAYINGYEISRDIVQIRKSLGLCPQHDVLFDYMTVAE
HLYFYAQMKGLSEQK-CPEEVNHILNILDLENKRHSLSKSLSGGMKRKVSVGIALIGGSK
---V-VMLDEPTSGMDPVSRRATWDLLQQQKSDRTIVLTTHFMDEADLLGDRIAIMAKGD
LQCCGSSLFLKHK-YGAGYHMIIVKELHCNTSDISH---LVY------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTALELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQELPLFFNFPP---PG--DAWELAYI
PSH--SDAARAITEWARRAL-------VVNMKVRGFPSEK-------HFEDYIRYDNR-S
SNVLAALVFENEFSHSTDPLPLAVKYHLRFSYTRRNYMWTQSGTFLLRDTEGWHTNSLFP
LF-PNPGPREPASP--DGGEPGYVREGFLAVQHAVDRAIMHYHANASAQQLLQQLT-VTV
KRFPYPPFISDPFLVAIQYQLPLLLLLSFTYASLTIIRAVVQEKERKL------------
---------------------------KEYMRMLGLDSWVHWNAWFLMFFLVLLVVVSFM
TLLFCVKVK-TG----VAVLTNSDPSLV----------------------------LAFL
LCFATSSISFSFMVSTFFSKA---NMAAAIGGFLYFFTYTPYFFVAPRYNWMALSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVSVDDDFCFGHVLGLLLLDSVLYG--
LVTWYVEAVFPGQFGVPQPWY-FFI------MPSY-WCGSPRTALGKE--EDADPEKALP
TEHCEAEPEALVAGI-KIKH-LSKVF-RVGNKDRAAVRDLNLNLYE---GQVTVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGQAYISGYEISQDMPQIRKSLGLCPQHDVLFDNLTVEE
HLSFYAQLKGLSPHK-CPEEVKQMLHVLSLEDKRDSRCRFLSGGMKRKLSVGIALIAGSK
---V-LMLDEPTSGMDAISRRAVWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYHMTLVKEPHCNPAGVSQ---LVRHHVPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKRQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAV--QLPALQYQH-ERRASDWAVDS---------------SLCGAL-DPTDGIGAL-
----IEEEPSMVKLNTGLALHWQ-QFWAMFLKKATYSWREWKMLA-AQILVPLTCVTLAL
LAINYSSEI-----LDDPLLRLTLGEYGRTVV---PFSVPGTSR-------LDQQLSERL
KDMLQAQGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAMSFGDAGEHTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFQLLCGPRAS
IEVSNYPQPRSALQAAKDQ-FSE-----GRKGFDIALNLLFAMAFLT---------ST--
FSILAVSERAVQAKHVQFVSGVRVATYWLSALLWDLISFLVP-----SLLLL--------
AVFRAFDVRAFTWDGHAAG-TLLLLLLYGWAIIPLMYLMSFLFSSAATAY------TRLT
IFNVLSG--------IATFLM---VTIMRIPAVKLEELA-RTLDRVFLVLPNHCLGMAVS
SFYE-------------NYETKH-YCTSSEIAAH-------YCKKFNIVYQENFFAWSAP
GVGRF--VTSMA---------------ASGCAYLTLLFLIETDLLWRLRNSVCAF-----
-RRRW---T--LAELCAQTALLPEDQDV-----AEERSRVLAPSLGPL--LDAPLIIKEL
SKVYEQR--TPLLAVDKISLAVQRGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEESITSGDAFVG
GHSISSDIGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAVVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------RGQQ---EALRDFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHDLSWAK--VFGTLEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTSEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLTLLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QSIQELPLFFSFPP---PG--GTWELAYV
PSH--SDAARTITETVKREF-------MVKMRVHGFSSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHSFNHSQDPLPLAVKYHLRFSYTRRNYMWTQTGNIFLKETEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIREGFLAMQHAVDKAIMRYHANTSAQQLFQKLM-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFFLIVVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFNKA---NIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSALYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVVGKEE-EGGDPEKALR
NEYFEAEPEALVAGI-KIKH-LSKVF-QVGNKDKMGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSLLTGLFPP-TSGRAYIHGYEISQDMVRIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQILHILGLEDKRDSRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKSGRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKQQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGAL-
----IEEEEVLVKLNTGLALHCQ-QFWAMLLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCLTLAL
LAINYTSEI-----FDDPLLKLSLSEYGRTVV---PFSVPGTSR-------LAQQLSENL
RDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSIKDRGELTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEISNYPQPRNTLQVAKDQ-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FAILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLVP-----SLLLL--------
VVFQAFSVQAFTRDGHMAD-LLLLLMLYGWAIIPLMYLMSFFFSAASTAY------TRLT
IFNILSG--------IATFIV---VTIMRIPAVKLQELS-RTLDHVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSELAAH-------YCKKYNIQYQENFYAWSTP
GVGKF--VTSMA---------------ASGGIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-RRRW---T--LAELQNRTSVLPEDQDV-----ADERSRILVPSLDSM--LDTPLIINEL
SKVYDQR--AALLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLINACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---EVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCGLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTLLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATLYPS--QSIQELPLFFSFPP---PG--ATWELAYI
PSQ--SEAVRTVVENVQRAL-------VINLRAHGFASEK-------DFEDYIRYDNR-S
SNVLAALVFEHTFNHSRDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTASLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMHYHANASAHQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLSIIRAIVQEKEKKL------------
---------------------------KEYVRMMGLSSWLLWTAWFLLFFLLLLVAISFM
TLLFCIKVK-KG----VAVLAHSDPALV----------------------------LLFL
ACFAVSSISFSFMVSTFFSKA---PSTAAIGGFLYFFSYIPYFFVAPRYNWMTLSQKLFS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFTFGQVLGMLLLDSVLYG--
LVTWYVEAVLPGQFGVPQPWY-FFI------LPSY-WCGRPRTVLGKEE-EDDDPEKVLR
TEYFEAEPEDLVAGI-KIKH-VSKVF-RVGNKGKAAVRDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEVSQDMDQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQVSQRGTG----------------------FAGCRGGPITREAASGAPSPP---
--------ANPTRPRAP-S-------------XRE----------GLSVGN-TGSGRFVH
LLCCERGWSLPTS-----------RDGRPRPWLLSG---VSQG--PLTSLD---DG---I
APALLP------------------------------------------------------
QLKAL--GAPTRRYSH-GSSMSGEDLGGGPGPSAP--------LSAGGP-RPTRAAGGRS
RAGSGRWLCHPGAPLSQLALHCQ-QFWAMFLKKATYSWREWKVVA-AQVLVPVTCLTLAL
LAINYSSEI-----FDDPLLKLTLGEYGRTVV---PFSVPGTSR-------LDQQLSEHL
KDMLQADGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDTGEHTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPRAS
ITVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLLSFLVP-----SLLLV--------
VVFKAFDVHAFTRDGHVAD-ALLLLTLYGWAIIPLMYLMSFFFSGAATAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDRVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSDVAAH-------YCRKYNIQYQENFYAWSTP
GVGRF--VTSMA---------------ASGFAYLTLLFLVEADLLWRLKTCLCAF-----
-QRRR---A--LTELYPRTAALPEDQDV-----TDERNRILSPNPGSL--LDTPLIIKEL
SKVYEQR--APLLAVDKVSLAVQKGECCFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RIGYCPQFDALLDHMTGRETLVMFARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY-SLSGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWGTVARARKSGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVGLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDDLSWAK--VFGVLEKAKEKYGVDDYSVSQTSLE
QVFLSFAHLQPPTEDAGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------FSCLNNIRCITREMIFGLL-----------
----------------------------EYQLMIGLSNWMLWAAYFVTFLLLYSITIIFM
CIIFFIKIK-P-----VPIIQHSDSTLI----------------------------FIFL
LFYAISTICFSFVITTLFNKV---SFAVALGQLIFFATFFLAIGLTFHTAQMNFTKKLAA
CLSSNFAMVLGVSLLVDAEIQ-EIGLKWSNIFSSTKL-DDFFFVYVLGMLLFDALLYG--
LVTWYIEAVFPGSYGMPKPWN-FFL------LRSY-WFGNPPEK--RP--EINQFYDAVL
HDYFEAEPTDLVPGI-QIQN-LCKVF-RVNNENKVAIKDLSLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

ST--TLSILSGLYPP-TSGKAYINGYNISRQMVQIRKSLGLCPQHDLLFNYMTVSE
HLYFYGVIKGIHQKA-IPMEINNMLSAFKLLEKHNALSKSLSGGMKRKLSVIIALIGGSK
---V-VILDEPTSGMDPASRRVTWDLLQQYKKDRTILLTTHLMDEADILGDRIAIMVRGS
LRCCGSSVFLKKL-YGVGYHIVMVKEPNCKVEEISK---LIQYYTPSATLE---NNVGSE
LSFILPKEYAHRFE---G-LFTSLEEGQKTLGIASFGASVTTMEEVFLR--VSHMEVSDN
KVQAV--Q--P-SQRS-KFSAKNQNRNVSRNA------------------TRSN------
--SPILNESQTIRFNTGCSLYNQ-QFRAMFVKRVMFNWRNWKLVL-LQILGLLGSFAFLL
TANNIF--------RVDDARKMDLGQYGHTVV---PFSVSGDPR-------LTMFLLHNF
ESIVKSENQRLKE-VQ-----VLRKSLLIFKQSDEISGYQELCIIALSIEAKANETKLTV
LFNNEAYHSP-----------------------------SVALALLDNVLFRSLSGSEAS
LTVSNKPQPRPDKKHS----RKG-----ITNGQEVAISLQFGTALLI---------SG--
FSLLTVTERTSKAKHIQFVSGVSVFVYWLSALLWDFIIFFIS-----CCLIM--------
GVLKYFKFDIYVMDYHILE-TMVIFILYGWAAIPFVYLMSFLFSKSTSAY------IILM
LLNYFSG--------TIGFFIGTALENEGKALDKLSKSLRHVK---ASLLPQTCFLKKIS
DFSL-------------SFHYRRRYCASAEI-S--VKY----CKSLGLGSRESFYAWQNN
MIGKY--LIIMS---------------IMGFLCLFLIFLGETTL-WRLRAFLNRYIRWA-
WR----LA---WLAEE--LSGKYEDEDI-----QNERKRVLEQTQ---ELLNSTLIIKEL
IKIYFTC--PVILAVKNISLAVQTGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFQILTGEDSTTSGDVIID
GFSITKNILKVRS-RIGYCPQFDALLEYMTAWEIMIMYARL-WGLSEDQIKPYVKKCLKS
LELE-PYADKLISTY---SGGNKRKLSTVIAIM---------GKPSVIFLDEPSTGMDPV
ARRLLWDKVTQTRESGKTIII--TSHSME----ECDALCT-----NLAIMVQGKFMCLGS
PQHLKSKFGNIYILKAKAKT-------K------DKLEDFKMFIKIT----F--------
-P-DSVL-----KHENQGILNYYIPRKDTGWGQ--VFGILEKAKEQFDLEDYSISQVTLE
QVFLSFADTDNR------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLTLLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QSIQELPLFFSFPP---PG--GTWELAYV
PSH--SDAARTITETVKREF-------MIKMRVHGFSSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHSFNHSQDPLPLAVKYHLRFSYTRRNYMWTQTGNIFLKETEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIREGFLAMQHAVDKAIMRYHANTSAQQLFQKLM-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFFLIVVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSALYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWH-FFL------MPSY-WCGNPRTVVGKEE-EGSDPEKTLR
NEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKMGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSLLTGLFPP-TSGHAYIHGHEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKSDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQRELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGTL-
----IEEEEVLVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCLTLAL
LAIHYTSEI-----FDDPLLKLSLNEYGRTVV---PFSVPGTSR-------LAQQLSENL
RDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDRGELTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPRAS
IEISNYPQPRNTLQVAKDH-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLVP-----SLLLL--------
VVFQAFNVHAFTRDGHMAD-LLLLLMLYGWAIIPLMYLMSFFFAAASTAY------TRLT
IFNILSG--------IATFIV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSELAAH-------YCKKYNIQYQESFYAWSTP
GVGKF--VTSMA---------------ASGGIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-RRRW---T--LAELQNRTSVLPEDQDV-----AEERSRILVPSLDSM--LDTPLVINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLINACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---DVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LKKLKLLLWKNFIL---KRRKTLITLLEMLMPLLFCAIVLYLRLNSM-PRKK--------
----------------------PSTSYPA--VDVSLLPVYFHNYP---VK--SKFRLAYI
PSK--SETLKAVTEVVEQTF-------AVDFEVLGFPSVP-------LFEDYIIKDPK-S
FYILVGIIFHHDFNSSNEPLPLVVKYDLRFSYVQRNFVSPPRHLFFQEEIEGWCTAFLYP
PN-LSQAPREFSYA--DGGNPGYNKEGFLAIQHAVDKAIMRHHAPKAALNMFKDLH-VLV
QRFPFGPHIQDPFLVILQNEF

PF12698 // ENSGT00760000118965_2_Domain_0 (382, 664)

PLLLMLSFICVELVITNSVLLEKERKQK-----------
----------------------------EYMCMMGVESWLHWVAWFITFFISVLITVSVM
TVLFCTKIN-S-----VAVFRNSNPILI----------------------------FIFL
MCFAIATIFFAFMMSTFFQRA---HVGTVIGGTVFFFTYLPYMYITFSYHQRTYTQKILS
CLFSNVAMATGVRFISLFEAE-GTGIQWRNIG---SVWGDFSFAQVLGMLLLDSFLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVESLFPRKFGIPKSWY-IFA------KK-------PVPAIPPL-LNIGDPEKPSK
GDFMQDEPMNQMNTI-EIQH-LYKVF-YSGRSKRIAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLSMNLYK---GQVTVLLGH-N
GAGKTT--VCSVLTGLITP-SKGHAYIHGCEISKDMVQIRKSLGWCPQHNILFDNFTVTD
HLYFYGQLKGLSPQD-CRKQIEEMLRMLGLKDKWNSRSKFLSGGMKRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1185)

SGMDSPSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSPSFLKQK-YGAGYYMTIIKSPLCDTSKLYE---VIYHHIPNAVLE---SSIGEE
MIFTLPKKTIPSFE---A-LFTELELRQTELGISTFATSVTTMEEVFIR--VCKLADPST
NVLTE--KRHSLHQLP-RH------HH--RVPIDR-------IK--SLHSRT--------
--FSVS-TEQPMRLNTGFCLLCQ-QFYAMLLKKITYSRRNWMLV

PF12698 // ENSGT00760000118965_2_Domain_2 (1185, 1717)

LAVQVLLPLAIIMLSL
TFFNFKLRK---L--DNVPLELTLQTYGQTIV---PFFIAENSH-------LDPQLSDDF
VKMLVAAGQVPLR-IQ-----GSVEDFLLKKAKEAPEGFDKLYVVAASFEDVNNHTTVKA
LFNNQAYHSP-----------------------------SLALTLVDNLLFKLLSGANAS
ITTTNYPQPQTAIEVSESI-LYQ-----GPKGHYLVVNFLFGIAFLS---------SS--
FSILTVGEKSVKSKSLQFVSGVNTAVFWLSALLWDLISFLVP-----TLLLV--------
LVFLWYKEEAFAHHESIPA-VVLIMMLYGWAVIPLVYTVSFSFNTPGSAC------VRLV
LMLTFLS--------ISPV--VL-VTVTSEKDLGYTELS-DSLDHIFLILPGHCLGMALS
NLYY-------------NFELKK-FCSAKNLSDIDCNDV-----LEGYVVQENIYAWESL
GIGKY--LTALA---------------VLGPVYITM

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFLTEANALYVLKSR-LSG-FFSS
FWKEK---SG--M-IFDVTEPEDE--DV-----LEETETIKRYLETLI--KKNPLVVKEV
SKVY-KD-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFVVKEEE-CFGLLGLNGAGKTSIFNMLTSEQPITSGDAFVK
GFNIKSDIAKVRQ-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPECHIKACVDLILGN
LLMC-VCADKLVKTY---SGGNKRMLSTAIALV---------GEPAVILLDEPSTGMDPV
ARRLLWDTVERVRESGKTIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGIGYSLQAKVQR-------KWQQ---QMLEEFKAFVDLT----F--------
-P-GSNL-----EDEHQNMLQYYLPGPNLSWAK--VFSIMEQAKKDYMLEDYSISQLSLE
DIFLNFTRPESSTKEKIQQGQAVLASPLPPS---NSRPILSPP-SRLSSQTPKPLPSPPP
SEPVLL------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MTM
GGNLKLLLWKNFIL---KKRKTPVTMLEILAPLLFSTVVMYLRLNSL-PQKR--------
----------------------PPLNYLA--INISLLPDFL-YFP---TE--TRYQLVYV
PSK--SETLKAVTETVRKSF-------DVEFEVLGHSSVP-------VFESYIIQDPK-A
FYVWAGIVLDHSFNDSKQPLPLEIKYRLRLSCIQRNSLISK-VTSYYDNLEGWGTSLLYP
PN-PSQVPRAFGHF--DGGLPGYSKEGFLALQHALDKAIMQHHAHNATAQLFEDLT-VLV
KRFPHGAHIQDMFLLTLQNEFPLLLMLSFICIELIIINSVALEKEKKLK-----------
----------------------------EYMCMMGVDNWQHWAAWFIVFFISTLIVISFM
TILFCSQVT-G-----VAVFRNSDPSLI----------------------------FVFL
LCFATATIFFAFLISTFFQRA---HVATAAGGIIFFFTYLPCLYLTFSYSQRTHFQKVAF
CLLSNVAMGLGVRLISAFEIK-GTGMQWENIG---SVSGEFNFSQVLLLLLLDSVLYG--
VVAWYVEAVLPGEYGVPKPWY-FFV------LPSH-WCGRSVPLTRSV-LDVGDPDKGPK
SKFIQEEPTNLAKGI-EIQH-LYKVY-HTGKNKHIAVQRLTMNLYQ---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TCYMLTGLLPP-SGGWAYVNGYEISRDMAQIRRGLGWCPQHDILFENFTVKE
HLSFYAQLKGLSGQR-CPEEVQRMLHVLNLEDKQPGRGRRPQPGPETWLCHPQWLPLCLQ
---V-LILDEPTSGMDAISRRAIWDLLQQHKSDRTVLLTTHFMDEADLLGDRVAIMAKGE
LQCCGSSLFLKQK-YGAGYYMTLVKKPHCSTEKISH---LIYHHIPNAILR---SNIGEE
LTFILPKKSIHRFP---S-LFTELELKKVELGIASFGAAVTTMEEVFIR--VNKLSDTNT
DIQAL--KIPLMQSQR-------------RVPISR-------IK--RIHSRI--------
--FSIR-SGLPIQLNTGLSLICQ-QFYAMFLKRVTFSWRNWMLMLTIQVLAPLGITIFSL
AFLNLER-R---M--DEVPLELTLKTYGQTIV---PFYISPNSR-------LGPRLSEYF
TNMLVSEEQIPLE-TL-----SSVEDLLLQKAEEEPEGFDYKYVVAASFEDSGNHTTVTA
LFNNQAYHSP-----------------------------AVALALVDNFLFKLLSGARAS
ITVINHPQPRSALEVSEDI-LYQ-----GPKAHFLIINLLFGIAFLS---------SS--
FSILTVKERSTKAKHIQFTSGIYVATFWLSALLWDLITSLVN-----SLLLL--------
VVFLYHQEEAFTHQASVPA-VMLAFALYSWASIPLIYLSSFCFRYEGGAF------VKLI
IILTFLS--------LGPL--IL-VSITSEKELGYTTVS-DSLDRTFLLLPGHCLGMALF
NLHY-------------NYGIHK-LCKTRNLNYSECNQI-----SEGHTIQESIYAWESL
GMGKY--LTALA---------------ISGSVYLMLLFLVDTNVLWGLKAR-FSD-LNR-
----K---RQSHV-LTHEAAAMPVDQDV-----EQEAEMVETYLEKLR--EENPLVLREV
SKVY-AK-KVPPLAVNKISFTVQA

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGINGAGKTSIFKMLTGEEPITSGDAFVR
GLSIRSHLREVQQ-WAGYCPQCDALFNHMTGREMLVMYARI-RGIPEHHIGACVEQILDD
LVMY-AYVDKLVKTY---SGGNKRKLSTGIALL---------GEPSVIFLDEPSTGMDPV
ARRLLWDTVARARDSGKAIVI--TTHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------DGQQ---EALEEFKAFVNLT----F--------
-P-GESL-----LPPLTSLVPIIHSGL-PPSQQ--VFDILEQAKMKFMLDDYSVNQVSLE
DIFLSFTCFVHPTKEEKKQGQAEPADHSSTSPPPS--PSPSQPPSPPTSQPPSHPPSPPT
SQPPSHPPSPPSPP----------SPPPS-------------QPPSP---TGSSPPSQPP
SP-------------------------------------------

-------------------------------------------------------MDSLW
LRQFSVLLWKNFLL---KIREMSGLILEMLLVFLFFLWTLTVRNYSE-KKLF--------
----------------------NSSTFDS--LPLT-LPSFLEI----

PF12698 // ENSGT00760000118965_2_Domain_0 (168, 662)

-PN--LTFELVYV
PSE--SDVAKRITEMVKEDL-------NFDFKVRGFSSET-------SFENYIRTENN-S
NPVMAAIIFDHDFKSSDENLPLTVKYHLRFSKYYSTSEDTI--PES-DKRTKWDTALLFP
ST-PPEFHRNPMED--DGGEPGYFREGFLTVQHSLDKAIMIYHGGEAAKQIFDNTE-IYV
KRFPYPEYYHDGFMWQFIIIFPWTALFTFSQVILIVVGTIMMEKEKRLK-----------
----------------------------EYQLMIGLSNAMLWSSYFITFLFLYAIVIIIL
CILLFYKIV-N-----ETVLQHSDVMLL----------------------------FVFF
LFYAIVSIMFGFMISTFFNKS---SLATSIASFLHFITFLPYLVFLRRYNEMSLSEKLAI
CLITNTALGLGTEKICKLEMK-GFGANWDNFYLKESPDDDLTLAHIMGMFLVTAFLYA--
L

ENSGT00760000118965_2_Linker_0_1 (662, 757)

VTWYVDAVFPGKYGVPKPWN-FFL------EKSY-WCGEPPLE--SQ--DISEISDILP
SDYIEPEPVGLVTGI-RIQH-LRKEF-TLGDATVVA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 913)

VKNLSLNFYE---GQISVLLGP-N
GAGKTT--TLSILTGFYLP-TSGKVYINGYDISKEMVEVRKHLGLCPQDDILFPKLTVSE
HLYFYCVIKGVPSQK-RTEEINKMLTACDLIHKRNEYSEKLSGGMKRKLSIMIAFVGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1239)

SGMDPVSRRATWNLIQLHKEGRTILLTTHHMDEADILGDRIAIMVLGT
LQCCGSSVFLKKL-YGVGYHIIMVKSPNCNVEKISE---MIKRHVPTASME---TNIAAE
LSFILPKEYTHRYGFKEN-LFLEIEQRKTELGIAGFGISMTTLEEVFFK--VSNQANYKV
NEEVL--QMSSEPTT--NTNENNQNVNASRNS------------------ERS-------
--VSDTNKNSDTSFNTGLALHKQ-QFHAMLLKRAGFNWRNWKILL-LQIGALVGFMYLQM
RRRTIP------ATLDEPAREMDLEQYGETIV---PFS

PF12698 // ENSGT00760000118965_2_Domain_2 (1239, 1718)

VSGSSN-------LTENFKKNL
EIILTDKKQKLKE-VQ-----GDLQEYL-----VKNNECLYSCIIAFSIEITKTNIAAIF
WFNNEAYHSP-----------------------------SLSLAVLDNIIFKILSGPNAS
ITVSNKPQPKYISHKKS---EIR-----ETPGLQIVFTLIFGMSIFV---------SG--
FCLLTVTERVNRAKHIQYLSGVYTFNFWVSAIFWDFIIYIFG-----CCLVL--------
MVFVITRSNTLIKNGNIMH-TAFIFILFGWCVIPFTYLLSYLYTTSTGAY------IKLF
ALHETLG--------FLGVVVDLVITIM----EGYKAARKNVVLNMLTLIPMYNFGMSIL
KFYD-------------LEETKK-LCASFPE-MANIPR----CK-----IEISVYSMEEN
GIGKY--VIAMA---------------VSGFLYILLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLLDTVS-WNVRALVYRSVLFG-
IFKKINK----VMSKE--FSGESDDEDV-----QNERQRIVEQPL---ESLNSTVVIKEL
TKVYFQC--PPILAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISVAIQGEE-CFGLLGLNGAGKTSTFQILTGEHIATSGDVFIK
GFSITKNILKVRS-KIGYCPQFDALLDHMTVQETMIMYARL-WGIPENDINSYVNDILKL
LNLQ-PHANKRTQTL---SGGNKRRLSTAVAIM---------GRPFVVFLDEPSTGMDPV
ARRLLWNIVTKTRESGKVIIL--TSHSME----ECEALCT-----RLAIMVQGKFRCLGS
PQHLKNKFGDVYTMFVKFKT-------GTDQ---NIIEYFKIFIANT----F--------
-P-GSAL-----KQETQGVLNFYIPSKENSWGK--VFGILEKAKEQFDLEDYSVSQITLE
QVFLTFANVDKPAGGSEKQAQ---------------------------------------
------------------------------------------------------------
---------------------------------------------

--ASPPLPPSLPTSASLGIHARSLQNVLL--HERPGVFLSLQLPP-----SLGPSGKMAV
LRQLALLLWKNYTL---QKRKVLVTILELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATLYPG--QSIRELPLFFSFPP---PG--AAWELAYI
PSQ--SDAVRTVVETVRRML-------VINMRARGFPSEK-------DFEDYVRYDNR-S
ANVLAAVVFEHAFNHSRDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLRETEGWHTTSLFP
LF-PSPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAVMQYHANASTHQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLSIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWTAWFLLFFLFLLITVSFM
TLLFCIKVK-KN----VAVLAHSDPSLV----------------------------LVFL
ACFAISSISFSFMVSTFFS-----------------------------------------
--------------------K-GTGVQWRDLLSPVNVDDDFSFGQVLGMLLLDSVLYS--
LVTWYVEAIFPGQFGVPQPWY-FFI------LPSY-WCGHPRTVLGKEE-EDDDPEKVLR
TEYFEAEPEDLVAGI-KIKH-VSKVF-RVGNRGKAAVRDLNLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMAQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKRMLHILSLEDKGDSRSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPTSGMDAISRRAIWDLLQQHKSDHTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISR---LVHHHVPNATLE---SSAGAE
LSFILPKESTDRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------HLCGMM-DPTDGVGTL-
-----IEENTAVRLNTGLALHCQ-QFWAMFLKKAAYSWREWKMVT-AQVLVPLTCITLAL
LAINYSSEI-----FDDPLLKLTLAEYGRTIV---PFSVPGTSR-------LDQQLSEHL
KDMLQAEDQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IMVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLS---------ST--
FSILAVSERAVQAKHMQFVSGVHVATFWLSALLWDLMSFLVP-----SLLLL--------
VVFKAFDVHAFTQDGHVAD-ALLLLMLYGWAIIPLMYLMSFFFSGAATAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDRVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCRKHNIQYQENFYAWSTP
GVGRF--VTSMA---------------TSGFAYLTLLFLIETDLLWRLKACLCAF-----
-QRRR---A--LXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXX--XXXXXXXXXX
XXXXXXX--XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX

PF00005 // ENSGT00760000118965_2_Domain_3 (1866, 2033)

XXXXXMRQ-RIGYCPQFDALLDHMTGRETLVMYARL-RGVPECYIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DRQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGNDLSWAK--VFGVLEKAKEKYGMDDYSVSQISLE
QVFLSFAHLQPPVEDEGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLLT
LNQFAVLMWKNFTL---KRRKHINSILEIFSSFIFPVVLLVFHILTD-IKST--------
----------------------GPYNFTS--QSINTLPSYIKNA--------SDWELIYI
PSN--IDVV

PF12698 // ENSGT00760000118965_2_Domain_0 (190, 665)

KEITENVKRNL-------NISLKVRGFSSES-------EFEKYILYDYE-S
QKVLAAIVFDCDFKNSSDPLPLQVKYHLRFTRVQRTIW--------WPDKAGWKTAYLFP
DH-PSQGPRNPNLN--DGGSPGYIKEGFLIIQHALDKAIMLYHESNLGKSLFDGIT-IFV
QRFPFPAHPYHGLLWVSSPFLPLIFILTFSPVVLSIMQYVVQEKEERLK-----------
----------------------------EYQLIIGLRNWIIWAAYFFTFFLLYIIIITLI
CVLFFIK---AN----EPILRYSDYSFI----------------------------FIFL
VCYAIASIFFSFMVSTFFNKA---HLAASAGHLMFFASFFPFNFIFQHYGAISVSNKVAA
CLSSNVALALGINLLVKLEIK-EIGVKWHNLWKPASLDDNLIFGYMLGMLLLDAFLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVETVFPGQSGVPQPWY-FFL------LRSY-WFRKPRIIEE-K--NIESHGRTQR
SNNFEAEPINLVAGI-QIKH-LH-----KEFSGKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 912)

KDLSLNVYE---GQVTILLGH-N
GAGKTT--ALSVLTGMYSPLSRVKAFVNGFDISDNMIEIRKNLGFCPQNDLLFKDLTLAE
HLFFYSVIKGMPRNM-HTLEIDHMLSIFDLLENRHAFSSSLSEGAKRKLSVIIALIGGSK
---V-IILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1297)

SSGMDPVSKRLTWNLLMQYKHNRTILVTTPYMDEADTLGDRIAILAMGT
LQCCGSSMFLKQI-YGAGYHIVMQREPHCDVEKISA---MIQSHVPGAMLE---DDIGDE
LSFVLPKEYTHRFE---A-LFDELEKNQKELGIANFGVSITTMKEVFFK--VNKLATSQM
SIHDQ-----------------NKQQSLSGSF------------------ERPV------
--FSSFNELATIKFNTGFPLYRQ-QFCSMFIKRALFSWRNWKLIL-LQIIVILVVTTYLL
IALNVK-------DDYMPAREMDLRHYGQTIV---PYSISGNSG-------LALTLIKKL
EIFLKSKNQELRK------------NYI-----LES

PF12698 // ENSGT00760000118965_2_Domain_2 (1297, 1717)

KECRDFCIIALSIKVEKNKTILTV
LFNNEAYHSS-----------------------------ATSLAVLDNILFMLLSGPRAS
ITVSNKPQPL--PVYGSNT---V-----PINGLQIVQCLAFGISIVA---------GS--
FCLQTVIERISKAKHIQFLSGVYVLTYWLSALLWDLICFSIP-----CCLLL--------
VIFKYCEVDAFVVNFNFLD-TMLIFMLYGWCIVPLMYLGSFLFSSGTAAS------IKLT
LFNYISI--------ICSIIVQSVLQFYE---NELSF-FRSIISNVLMVLPSYNFAMSIS
RYFD-------------DYEVKK-LCAKKF--KSIYLD----CNKS--FIQNNIYSFGEH
GIAKF--LITLA---------------VMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFSLETAF-WSLKNFVFHNIIFN-
FFSVFTRLKT-VIPNQ--GTKEQEDEAV-----IKEKNKVLELL---RTFQTNPVLLNKV
TKIYYKC--PVVRAI

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLVVKKSE-CFGLLGLNGAGKTTIFKMITGEETITSGVVLID
GNSVTENIRKIRS-RIGYGPQSDSVLNHMTGRELLIMYARL-WGVPESVIYKYVEAFLCS
VHLE-PFADNVVYTY---SGGNKRRLSTAIALM---------GKSSVVLLDEPSTGMDPV
TRHLLWDTVTWICKTGKAIII--TSHSME----ECEALCS-----RLAIMVKGMFVCLGS
PRHVRNKFGNIHTLTAKINI-------SKDE---DKVKEFKKFVEKT----F--------
-P-GNIQ-----NQEYQGIIGYFIPSKEICWGK--VFSILEKAKVLFNLEDYSISQITLE
QIFLTFANIDKKESTQSINLT---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASLE
SQKLLILLWKNFTL---KRRKFGA

PF12698 // ENSGT00760000118965_2_Domain_0 (85, 665)

LVFEIILMFVFSIILLVARKLLA-VKKM--------
----------------------ESFHFPV--QRVSNVPSFIQVFT--TSS--HPWELAYV
PSN--SIMVQNIIENVKRDL-------NFHMKVTGFSSES-------DFEDYMSSTVS-S
KTVLAAIVFDHSLTNSDDPLPKKVKYYLRFSNIKKNMN-A----SAYFQEHTWFTSFLFP
PG-HLEGPRNLFDE--DGGSPGYISEGFLAVQHALDKAIMRHHGGAAATALLKDTS-LFI
QRFPTPAFHHDFFHKLANILIPLTMACTFLVNYLTLVQSIVWEKENRLK-----------
----------------------------EYQLMIGLSNWMLWVAYFITFFCLYFINIIFI
CVILFFKTE-P-----ARIFQYNDPILV----------------------------FVFL
SLYASSSIFFSFMVSTLFNRV---NFAMSLGSSFFLLTYFPYVIMYSKYEQMTFKQKLIW
CFDYNVGMAFGFKFLIDAETK-KTGVKWSNIFSSADK-DSFSFAYVLGMLLVDAFLYA--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGEYGVPKPWN-FFM------THSY-WFGDTPQT--NP--EITQFHETIQ
SKYFEAEPADLMPGI-QIKH-LHKVF-QENNTTKIAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

EDLSLNIYE---GQITVLLGH-N
GAGKST--TLSILSGLYPP-TRGEAYVYGYDISQNMAQIRKSLGLCPQQNLLFDHLTVSE
HLYFYCRVKGVPQKV-YLKETNNMLSAFNLVEKHDAFSKSLSGGMKRKLAIIIALIGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1189)

SGMDPASRRATWDLLQAYKQDRIILLTTHYMDEADMLGDRIAIMVQGT
LRCCGSSVFLKRQ-YGIGYHVVMVKEPHCDTDEISK---LIHDYASTATLK---TNVGNE
LSFILPLEYTQRFE---A-LFTALEENQERLGISSFGVSITTMEEVFLR--VSHMQD---
-IQAT--QSPP--VGG-KE---NKNKGVPS-S------------------TRGG------
--FPTQNEDPPTVFNTGCSLYCQ-QFHAMFIKRMVYNWRNWKTLL-VQ

PF12698 // ENSGT00760000118965_2_Domain_2 (1189, 1718)

ILGLVISALFLL
KSHDLS-------YKDEKTRRMNLDEYGQTIV---PFSISGKSN-------LTTSLLTHL
ENMLKPGNHKLKE-VQ-----GDLLKYL-----EGNEDCIHSCIIALSMEVVANRTEITV
LFNNQAYHSP-----------------------------SLSLAILDNILFMSISGADAS
ITVSNKPQPDPQAKRT----LG------SVEGKVVALKIQLGMALLV---------SG--
FCLLTVTERTTKAKHMQFLSGVSVLVYWLSALMFDFIIFFIS-----CCLLL--------
VVFKYCKIDIYVTDYHILE-TMLILTLFGWSAIPLTYLMSFLFSKSTSAY------IKLI
MFNYVSG--------IFSILIDT--VIVSQLPTTMSNTTKTFLLNTLLLFPTYNLGKCIG
DYTV-------------IYQRKI-QCIQKNN-VPNYLN----CSKE--SIERNIYSLKEH
MIRKY--LIAMS---------------ITGLVFLLFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENIV-WKLRMLIHQYIYFG-
VYKKYKTD---IISKE--LSGESEDKDV-----ENERKKILHQPE---EFLNSPVLIKEL
TKIYFKY--PFILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAVQERE-CFGLLGFNGAGKTTTFQILTGEKTPTTGDVFID
GISITKNILKVRS-KIGYCPQFDALLEYMTGREIMIMYARI-WGVSEHQIQPYVNKYLNS
LDLE-PHSNYLISTY---SGGNKRRLSTAIATM---------GKPSVILLDEPSTGMDPK
ARRLLWDTVIKTQESGKAIII--TSHSME----ECEALCT-----RLSIMVKGKLTCLGS
PQYLKNKFGDVYILKAKVKS-------E------ETVKDFKSFIRLT----F--------
-P-GNDL-----KQENQGILNYYIPSKDNSWGK--MFGILEKAKEEFNLEDYSISQITLD
QVFLAFANQDRK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLLD
FKKLMILLWKNFTL---KRRKCMALVVEILIAVMFGISLLGLRNIII-LKKT--------
----------------------GPFNYTA--FPVNHKPSFIEAPV--TFP--YPWELAYI
PSK--

PF12698 // ENSGT00760000118965_2_Domain_0 (186, 665)

SAVVQNIVENVKKDL-------NTNMKVVGFSSER-------DFENYLKQSKN-S
EKVLAAIVFDHDFQNSNDAVPLKVKYYLRFSYFKKNKS-------V-SQLAGWFTNSLFP
LL-P-LEPRDVQAA--DGGRPGYISEGFLLVQHALDKAIMLYHSGTAAETLFNSVN-IFV
QRFPYPLQNTDLFFVIAAIIIPVIVAFVFSMNHLTLVQSIVWEKENQLK-----------
----------------------------EFQLMSGLSNWMLWTAYFITFLFFYLFDIIFM
CFIFFVKIE-P-----APVFQYSDPSLI----------------------------FVFL
LFYAIAIIFFSFMVSTFFDKT---TVAVIFGGFIFLIIYIPSTLLVSDYNKMIFHQKLIS
CLSFNVAMALGFKFIAEAEAM-KTGVKWSNIFSSTHL-DDFLFVYVMGMFLLDSFLYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVGAVFPGKYGMPKPWN-FFL------MRSY-WARKQHAT--KG--ETIQYEKTVQ
SKYFEDEPTDLVAGI-QIKHVHK-VF-QENNTIKVAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQITVLLGP-N
GAGKST--TLSILSGLYPA-TSGKAYINGYDISHDMNQIRKSFGVCPQKNLLFDYLTVSE
HLYFYCMIKGVPHKM-CLKEIGHMLSVFKLLEKQSAFSKSLSGGMKRKLSIIIALIGGSK
---V-VIVDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1186)

SGMDTASRRATWDLLQNYKQGRTILLTTHYMDEADVLGDRIAIMVNGS
LKCCGSSMFLKHL-YGVGYHIVMVKAPHCDVEEISK---LIHHYAPNATLE---SNVGTE
LSFILPKEYTDRFE---D-LFTTLERRQDELGINDFGASVTTMEEVFLK--VSHME-SQT
DIQAT--Q--SLSQRS-KVLTMRQNSNMSNNV------------------KRTH------
--SLNEN---TTVFNTGSSRYCQ-QFHAMLLKKLLFSWRNWKLIF

PF12698 // ENSGT00760000118965_2_Domain_2 (1186, 1718)

-LQIFGLLIPTILLF
QDSDFK------IADEETSRQMNLDEYGQTIV---PYSISGNST-------LTISLLKHL
ESMLAPKNHILRE-VQ-----GDVVNYL-----RENKECITMCIVALSIEVRTNETIFTA
LFNNQAYHSP-----------------------------SLSLSVLDNIIFMSLSGADAS
ITVYNKPQPPPKKTKIKQ--VER-----TMNGQEVAIKLQLGIALLI---------SG--
FCFLTVTERITKSKHIQYLCGVSTLVYWLSALLYDFIIFFIS-----CCLLL--------
GIFKYHKIDIYVMDYHFLE-TMLILTLYGWSSIPLIYLMSFLFSKSTSAY------IKLV
LFNYISG--------TYSILIE--QLLKTKMESGMSNTTQALIRNMLLLLPNYNLVKCVS
DYTE-------------VYRVKI-LCTQ-KT-VNYLLN----CSKE--NTEKSIYSLENH
MIGKC--LIAMS---------------ILGFVFLIFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FLWENAL-WRLRAFIHQYIYFG-
IYKKFKKD---LMSQE--LSGKSEDKDV-----QDERTRILEQPE---ELLKSPLLIKEL
VKIYFKY--PVILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAVQKRE-CFGLLGFNGAGKTTTFEILTGELSPTSGDVFID
GFNITKNNLKVRS-RIGYCPQFDALLDYMTGKEIITMYARV-WGVSEHQIPLYVDKHLKS
LELE-PHANNLINTY---SGGNKRRLNTAIAVM---------GKPSVIFLDEPSTGMDPV
ARRLLWDTVTKTRERGHAVVI--TSHSME----ECEALCT-----KLAIMVKGSIMCLGS
PQHLKNKFGDIYILKAKFKT-------P------DKVPNFKNFITMT----F--------
-P-GSIL-----KEENQGILTYSIPRKDNSWGK--VFGILEKAKVEFSLEDYSIGQITLE
QVFLTFANPDNAE--DDFEEK-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MTM
FRNLKLLLWKNFIL---KKRKTLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLEILMPLLFCAVIIYLRFGSL-PRKR--------
----------------------PPVDYNV--IDITSLPEFFNQFP---LK--NKFQLVYI
PSK--SETLKNITEMVKDFF-------TVEFEVLGYSSVP-------LFEKYIIQDPK-A
FYVLAGIVFYHNFNDSTEPLPLEVKYYLRFSFFQRNYLSLR-LILQQDDMQGWLTSFLYP
PN-LSQEPRDYGVS--EGGAPGYYQEGFLAIQHATDRAIMWHHAPAEATGLFQSLS-VLL
KRFPHGAYVRDLFFLVLQNEFPLFLMLSFICIELITINSIVLEKERKLK-----------
----------------------------EYMCMMGLHSWQHWVAWFIVFFISASIVVSFM
TFLFCIEFD-E-----SAVFGKSDPSLI----------------------------FVFL
MCFAIATIFFAFMISTFFQKA---HVATASGGIIFFFTYLPYLYLTFTYTQRSFFQKITF
CLLSNVAMALGVRLISTYEAR-GTGVQWRNMG---HIGGEFNFTQVLLMLLLDSVIYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGEYGTPKPWY-FFL------MV------KPISLRNPV-LDLEDPQQALG
NKFIQDEPTNLIKGI-EIQH-LYKVF-YKGRDEHVAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLTVNLYQ---GQITVLLGH-N
GAGKTT--TCSILTGLITP-SSGQAFINGYEISQDMLQIRKTMGWCPQHDILYDNLTVAE
HLYFYAQLKGLPRQK-CPEEVKRMLHVLGLEEKRDSRSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1184)

AGVDAVSRRAIWDLLQQHKSGRTVLLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKEK-YGAGYYITLVRKPRCDTEKISL---LVYQHIPNAVFQ---SSIGEE
LTFILPKESTHRFE---A-LFTDLELRQEELGIASFGVSCLNP-----------------
-----------FYNIL-TEYRVPVN---------R-------IK--RLHSRI--------
--FSIP-SGLPIHPNTGFSLLCQ-QFYAMFLKRATYSWRNWIM

PF12698 // ENSGT00760000118965_2_Domain_2 (1184, 1718)

MLSIQILVPLVILSISL
SFLNFDI-S---M--DNSPLELTLKSYGQTIV---PFYISPNSR-------LGPQLLDHL
TDVLMAEDQNPLE-LQ-----SPVEPFLLKKLEEEPEVFDQNYLVAISFDDVGNHTIVTA
LFNNQAYHST-----------------------------AQVLALVDNILFKLLSGPRAS
ITVLNHPQPQSSMEIAEDI-LYE-----GPKGHYLVINLLFGMAFLS---------SS--
FSILTVKERGLKAKQIQFISGVHVATFWLSSLLWDLLSFLVP-----SLLLL--------
VVFLYYDEEAFTHEENVPA-VFLMLMLYAWAIIPFIYLTSFCFDNAGNAC------VKLI
IMLTFLS--------IGPF--VL-VSVTSEKELGYTAIS-ESLDNMFLPLPGHCLGMALS
NLYY-------------NFELQK-FCKVKTALCNLIMSI-----SEGYVVQEDIYAWESL
GTGKY--LTVLA---------------ILGLVYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLTETNVLWELKSR-FSG-LS--
-WKQK---MVK---------SVPGDQDV-----EEEAKMIKNSWEDLC--KKNPLVLKEL
SKVY-SR-KVPPLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFAVRAEE-CFGLLGFNGAGKTTIFKILTGEESITSGDAFVN
SISVSSDLRKVRQ-WIGYCPQVDALLDHMTGRETLVMFSRL-RGIPERHISSCVDQILDD
LLMY-TYADKLVKTY---SGGNRRKLSAGIALL---------GEPVVIFLDEPSTGMDPV
ARRLLWGTVARARKSGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVGLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDELSWAK--VFGIMEQAKATYVLEDYSVNQVSLE
DIFLSFSCPVPPARGSNRQERAKPADPTFPC------PPLSPSSSQRPSPPPTPPPTPSS
SQPFSWSPTPIPFR----PSSW-----------------SSSQPPSL---PRSPPASQPP
SP--HPSKTALL---------------------------------

-----------------------------------------------------MGKFKLL
LKQLSLLLWKNYII---KKRMWIITLLEIILELLFAILLLMYRKYIP-TEHV--------
----------------------DSVSYNI--QQIETLPSFFQT------S--TQWELIYV
PSN--SEVVKNITKRAQKTL-------GNNIKVRGFSSER-------AFESYVRYHNE-S
SNVLAAVVFEHTFRHKLESLPLKVRYHLRFSFSPRNTLVTGRLFLMPEEPEGWRTALLFP
LY-PLPGPRNHFAS--DGGNPGYISEGFLTIQRAVDKAIIEYHGKDGGKWLNDHVT-VSV
KRFPFPPFVSDNFLKFLDQVLPLIILLLYSLNVLMIIRVIVQEKEKQLK-----------
----------------------------EYLQMMGLSNWLLWSSYFITFFFSFLITICLL
TLFFFMQV------FDQPIIYHSDSSLV----------------------------FIFL
LCFALSSMFFGFMISTFFNKA---NMAVATGGCIYFITYLPYLFISSRYNQMSLDQKLAA
CLLSNIAMTMGINMIVRFEIK-GIGVHWERLTDTVSIDDDLNLGHILGMMLVDAFCYG--
LAGWYMEVVFPGEYGIPQPWY-FFL------KRSY-WYGYPKPLFRSH--KDS--EDNSQ
NQYMEAEPVGLVAGV-QIKN-LSKVF-VIGRRVKEAVKDLTLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLYPP-TSGRAYINGFDITRNMIDIRKSLGLCPQHDLLFDSLTVTE
HLYFFAMLKGFPKRK-LKNEINFMLHIFNLEDKRNEFSSKLSGGMKRKLSISIALIGDSK
---V-VMLDEPTSGMDLISRRATWDLLQKQKSRRTILLTTHHMDEADLLGDRIAIMAKGG
LQCCGSSLFLKKK-YGAGYRLIMVKEPQCQIKKVSQ---LINQFVPNATLE---SNVGAE
LSFILPKEDAHKFE---D-LFTELENKRKSLGIASFGTSVTTMEEVFLK--VGKMVDSKM
DLQAI--KVSDSNKEF-LRQASRMSLEGEDMGIYLRDPESEEEDEIEYH-TDKNDEK---
--LPRIHHYLPVKFNTGIYLFSQ-QFYAMLVKRATFSWRNWKLIL-LQIMVLLTFTAILL
RAITFYSEI---N--DDPQLDMSLRHYGRTIV---PFSISGGTE-------LSRQLGEYM
QTLLIDDRQVPQF-VK-----GSLDEFLLSDRL-----CEGQCIIAIEIDSHDNKTEITA
LFNNQAYHSP-----------------------------AAALSLVDNMLLLSRSNTRAS
ITISNKPQPRSAIKAARET-YHK-----GSRGQEIAFSLFFGMAALA---------SS--
FCLLTVTERIIKAKHLQFVSGVGIINFWCSAFLWDLFIFFIP-----CLLLL--------
MVFKICHMDAFVEDFHFIN-TLLIFLVYGWSVIPLMYLMSFFFSSSATAY------AKLV
VFNFFSG--------MISF--LF-VYMAKSKVVVMTNSSIELLDNIFMIFPNHNLGKSIS
GFYE-------------NYKAQK-YCTSVAS--KDCESK-----GI--TYEKNFYSLIGN
GIGKY--IIAMA---------------VSGLIFLLVLFLIESKS-WRLKNL-LDRFMFFY
CY--R---GWYSKQHRN--KGIIEDKDV-----TKERKKVRDYPVEAMVALEIPLVIRDL
VKIYYRK--VPVLAVNNISLAIMRGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

STTFKMLTGDETISSGNAYFS
GVSISSQIRTVQR-RISYCPQLDALLDYMTGRELMYMYARL-WGIPENHIKHYVKNMLKA
LLLE-SNADKLIRNL---SGGNKRKLSTCISLI---------GRPSVVFLDEPSTGMDPV
ARRLLWDTLVRTRESGKAIVI--TSHSME----ECEALCT-----KLAIMVAGKLKCLGG
PQYLKNKFGSGYTLVAKLKN-------NYTE---DDMEQFKKFIETT----F--------
-P-GSIL-----QYEHQGIIHYNIPSENFSWAK--VFGILEKEKDINKLEDYTISQITLE
QVFLSFAESEKTENEDDD------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
FRQLVLLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPD--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHTFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSLLLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADTTTRQLFQKVT-VIA
KRFPYPPFIADPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLLLLIAVSLM
TLLFCVKVK-KD----VAVLSSSDPSLV----------------------------LAFL
LCFASSSISFSFMVSTFFSKA---NMAAAIGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFV------MPSY-WCGNPRMVTGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKAF-RVGTKDKTAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSVLTGLFPP-TSGRAYINGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSHQK-CPEEVKQMLHILGLEEKWNSRSKFLSGGTKRKLSIGIALIGGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKSDHTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPESISQ---LVRHHVPNATLE---SNAGAE
LSFILPKESTHRFE---G-LFATLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGAL-
----IEEECTTVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1716)

WKMVV-AQVLVPLTCITLAL
LAINYSSEI-----FDDPPLKLTLGEYGRTVV---PFSVPGTSR-------LDQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLIAASFRDVGEQTVITT
LFNNQAYHSP-----------------------------AAALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FSE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVRVATFWLSALLWDLISFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIEYQENFYAWNTP
GVGRF--VVSMA---------------TSGCTYLI

ENSGT00760000118965_2_Linker_2_3 (1716, 1816)

LLFLIETNLLRRLKSFFCAF-----
-WRRQ---T--LTELYTRMSVLPEDQDV-----ADERSRILAPSLDSL--LDTPLIIKEL
SKVYEQR--MPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DKISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESITSGDAFVG
GHSISSDIGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPECHIDACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSAGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTMARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGIGYSLRAKVRS-------EGQR---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPSHNLSWAK--AFSILERAKEKFSVDDYSVSQISLE
QVFLGFAHLQPPTVDEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLR
MKQFSILLWKNFLL---KRRNVIGLVVEILLIFLLFTWTLTIRRITK-KTFS--------
----------------------QATTFYP--IPLT-LPKFIN------KK--FEYE

PF12698 // ENSGT00760000118965_2_Domain_0 (177, 663)

LAYV
PSE--SHAARNITEMVKKDL-------NFNFKVRGFSSEE-------SFEKYIKYENK-S
AYVLAAIVFDHVFKTNNERLPLQVKYNLRFGRLYDIYNPLK--PYKGQDRKDWNTSVLFP
SM-PSLGPRNIMEN--DGGHPGYIREGFLIVQHSLDKAIMVYHSGRAAEDMFANAT-FYA
RRFPYPAFTLDNFLWTFMPMFAWTILFTFTQMTLVVVGTIMMEKEKRLK-----------
----------------------------EYQLVVGLSNAMLWVSYFITFLVMYFIIICLL
CGILFLKIT-H-----ERVFQHSDPLFI----------------------------AFYL
LCFAVSSVLLGFMISTLFDKA---SLATSIAGFLHFLTFFPYLIVVSMYSQISFGGKLAL
SLITNTALAFGADLICKMEMK-GHGAQWYNFATKISVDDDLTLAHIIGMFLFSAFLYG--
LV

ENSGT00760000118965_2_Linker_0_1 (663, 758)

AWYIDAVFPGKYGVPKPWN-FFL------LKTY-WFGEPVLS--K---EESQVSDLPS
RKFIEPDPVGLTAGI-QIQH-LYKKF-TLKNSTLMAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSILTGLYLP-TRGKVFISGYDISSDMVQVRKSLGLCPQDDLLFPMLTVLE
HLYFYYVIKGIRSKK-RAREIDEMLTSFDLLDKSNTLSKDLSGGMKRKLSIIIALIGNTK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1190)

SGMDPVSRRTTWDLLQQYKENRTILLTTHHMDEADVLGDRIAIMVSGT
LQCCGSSFFLKKL-YGVGYHLVMVKTPECDVEKISQ---LIRDHIPTAEME---MNVAAE
LSFILPKEYTHRFA---E-LFTDLEERQEELGIIGFGVSMTTIDEVFFK--VGNPPDLKL
STETI--ESASSGDQ--SRNEDIQNINVPRNF------------------DRP-------
--DY-LRGLFNSSFNTGWALYIQ-QFRAMLIKRAMYSWRNWKQLL-LQL

PF12698 // ENSGT00760000118965_2_Domain_2 (1190, 1718)

LTLLGLMYLLT
EGISFP------T-PEMPARVMDLKQYGETIV---PFSISGDPH-------LTQSLTKNL
EIILKAKKQKLHE-VQ-----GDVQSYL-----VTKKECIYSCIIAFSLHVTRDKKTFTF
WFNNEAYHSS-----------------------------SLSLSVLDNIIFMSLSGADAT
ITVSNKPQPRQVIENKY---KKR-----HIQGFEIVLNLLFGMSIFT---------SG--
FCLMTVAERVSKAKHIQFVSGVYTFNFWLSALLWDLTIHFVA-----CALLL--------
LVFLITDIHVLLEKYHFLD-TMFILMLFGWSIIPFIYLLSFWYNNSTSAY------IKIF
VLNQCLG--------FMSVIVDAVVHII----PDIRNSTKNLILNSMLLLPVYNLGMSIN
KYYN-------------IHELRK-ACSSPNF-V-VFKD----C-HD--INNLPIYGMDKN
AIGRH--VTAMA---------------VTGATYLFLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLLELTT-WNLKTFIYRYVLFG-
IYRIFSKA---RVSKE--LSGESEDEDV-----QNERETILKNPQ---QSLNSCVLIKEL
IKIYFNI--PPTLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISVSIQKEE-CFGLLGLNGAGKTTTFEILTGEQIATSGDVFIE
DYSITKNILKVRS-KIGYCPQFDALLDYLTTQEILTMYARV-WGIPEKNIRAYVDNLLEM
LNLQ-SQAEKFIYTL---SGGNKRKLSTAIAIM---------GKSSVVFLDEPSTGMDPL
ARRMLWNTVTRTRESGKIIVI--TSHSME----ECEALCT-----RLAIMVQGKFVCLGS
PQHLKNKFGNVYTMNIKFKT-------GTDG---DVIMDFKNFITKV----F--------
-P-GSKL-----KQENQETLNYHIPSKDNSWGK--VFGILEEAKEQYNLEDYAISQITLE
QVFLSFANTDNTETGYTKAKE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------NG--
FCLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1445, 1715)

TVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
GVIKYHKLDIYVTDYHILE-TMLIFTLYGWSAIPFVYLISFVFSGSTSAY------IKLL
LLSYFSG--------TFGFLIG--EIIENKKLTNISNTTRTVVRNSLLLFPNYNLAKCVS
QYTT-------------IYDVKI-LCTTLKK-HSVHLN----CSKA--NTEKNIYSLEEP
MIGKY--LIDMS---------------TAGFIFL

ENSGT00760000118965_2_Linker_2_3 (1715, 1815)

VLIFFWETTS-WRLRTFLNQYIYFG-
IYKRYRKE---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLDSIVLIKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIKLYVNKWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSIIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLEDFKRFVITT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------NG--
FCLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1445, 1715)

TVTERTTKAKHIQFVGGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
GVIKYRKLDIYVTDYHILE-TMLIFTLYGWSAIPFVYLISFVFSGSTSAY------IKLL
LLSYFSG--------TFGFLIG--EIIENKKLTNISNTTRTVVRNSLLLFPNYNLAKCVS
QYTT-------------IYDVKI-LCTTLKK-HPVHLN----CSKA--NTEKNIYSLKEP
MIGKY--LIDMS---------------TAGFIFL

ENSGT00760000118965_2_Linker_2_3 (1715, 1815)

VLIFFWETTS-WRLRTFLNQYIYFG-
IYKRYRKE---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLDSIVLVKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIKLYVNKWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSIIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLEDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LQQLALLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SEAAKTITETVRKSL-------VINMRVRGFPSEK-------DFEDYVRYDNH-S
SNVLAAVVFQLASNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGNFFLKKTEGWHTTSLFP
LF-PNPGPREPAFP--DGGEPGYIREGFLAVQHAVDKAIMYYHANASAHQLFQKLT-VVA
KRFPFPPFISDPFLVAIQYQLPLLLMLSFTYTSLSIIRAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLIVVSFM
TLLFCVKVK-KD----VAVLSSSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPRYNWMTLTQKLFS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVVGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKTAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVVE
HLYFYAQLKGLSQQK-CPEEVKQMLHILNLEDKRNSLCKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSVGAE
LSFILPKESTHRFE---S-LFTKLENKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGTL-
----IEEEHTVVKLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCVTLAL
LAINYSSEV-----FDDPSLKLSLSEYGRTVV---PFSAPGTSR-------LDQQLSELL
RDVLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPRAS
IVVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWFSALLWDLISFLVP-----ALLLL--------
VVFRAFDVRAFTRDGHMAD-VLLLLMLYGWAIIPFMYLMSFFFSGASTAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSEVAAH-------YCKKYNIKYQENFFAWSAP
GVGRF--MTSMA---------------ASGCAYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-QKRW---T--LEELHNRTSVLPEDQDV-----ADERSRVLAPGLDIL--LHTPLTIREL
SKVYEQQ--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLTVQKGE-CFGLLGFNGAGKTTTFKMLTGEEPITSGDAFVE
SYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPEHLIDPCVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GDPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGGNLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASLE
SKKLLILLWKNLTL---KRRKFGALVTEIALLLILSVVLLVTRSLLP-IKKV--------
----------------------KSFQYPD--QPASDVPSFIQVFT--TIS--HPWELAYV
PSN--

PF12698 // ENSGT00760000118965_2_Domain_0 (186, 665)

SIMVENIVENVKKDL-------NFHMKVTGFSSEI-------DFEDYIRSTVN-S
KHVLAAIVFDHSFTNSNDPLPKKVKYYLRFSSVKKNIN-S----GAYFQGHSWFTNLLFP
PV-HLLGPRNQFDA--DGGSPGYISEGFLAVQHALDKAIMLHHGGAAATALFNDIS-LFI
QRFPYPEYHHDFFYTFANTFIPLIMACTFFMNYLTLVQSIVWEKENQLK-----------
----------------------------EYQLMIGLSNWMLWVAYFFTFFCLYFINIVFI
CVVLFVKIE-P-----APIFQYNDPILV----------------------------FIFL
SFYGISSIFFSFMISALFNRV---NFAVSLGSCFFLLTYFPCITIYSNYEHMTFKQKLIW
CFNFNVGMAFGFKFLIDAEAK-KTGMKWSNIFSPVDT-DNFLFAFVLGMLLVDAFLYA--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGEYGVPKPWN-FFM------MRSY-WFGETPQR--NP--QITQFNEKIR
SKYFEAEPADLMAGI-QIKH-LHKEF-KGGNTTKIAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

EDLSLNFYE---GQITVLLGH-N
GAGKST--TLSILSGLYPP-TRGEAYIHGYDISQHMAQIRKSLGLCPQQNLLFDHLTVSE
HLYFYCRVKGIPQKM-CLEEIDSMLSAFNLLEKRDAFSKSLSGGMKRKLAIITALLGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1312)

SGMDPASRRTTWDLLQAYKQGHTILLTTHYMDEADVLGDRIAIMVQGT
LRCCGSSVFLKRL-YGVGYHIVMVKEPHCDIDEISK---LIHYYASTATLK---TNVGNE
LSFILPQEYTHRFE---A-LFSSLEENQENLGISSFGVSITTMEEVFLR--VSHMEDSKS
DNQDT--QSPS--VGS-KE---NKNKDVPS-S------------------MRGG------
--FPIKGEDLAIVFNTGCSLYYQ-QFHAMFIKRLMYNWRNWRVLL-VQILGLVISSLFLL
KSHNLR-------YEDEKTRQMNLSEYGQTIV---PFSISGKSS-------LTTSLLLHL
ENMLKPGGHKLKE-VQ-----GDLLKYL-----EGNKECIHLCIIALSIKV

PF12698 // ENSGT00760000118965_2_Domain_2 (1312, 1718)

VANRTKLTV
LFNNEAYHSP-----------------------------SLSLAVLDNILFMSLSGADAS
ITISNKPQPRSQAKES----LG------SAEGKVVALKIQLGMALLV---------SG--
FCLLTVTERTTKAKHIQFLSGVSVLVYWLSALLFDLIIFFVS-----CCLLL--------
VVFKYCKIDIYVTDYHFLE-TMLILTLFGWSAIPLTYLMSFLFSKSTSAY------VKII
MFNYVSG--------IFSILIDT--LLVAKMPVTLSNTTKAFLLNTLLLFPTYNLGKCIG
DYTV-------------IYQRKI-QCTQQKN-VPKYLN----CSKE--NIEQNIYSLKEH
MIGKY--LIAMG---------------ITGLVSLLFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENTF-WKLRMLIHQHIYFG-
VCKKYKTD---KISKE--LSGESQDKDV-----ENERRKILCQSE---KFLNSPVLIKEL
TKIYFKY--PLILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAVQERE-CFGLLGFNGAGKTTTFQILTGERTPTTGDVFID
GISITKNILKVRS-KIGYCPQFDALLEYLTGREIMIMYARI-WGVSEHQIQPYVDMHLNS
LGLE-PHANFLISTY---SGGNKRRLSTAIATM---------GKPSVILLDEPSTGMDPR
ARRLLWDTVIKIRESGKAVII--TSHSME----ECEALCT-----RLSIMVKGKLTCLGS
PQYLKNKFGNIYILKVKVKS-------E------ETLKDFKNFITLT----F--------
-P-GNDL-----KQENQGILNYYIPSKDNSWGK--MFGILEKAKEQFNLEDYSISQITLD
QVFLAFANQDKK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QSIQELPLFFEFPP---VG--GTWELAYI
PSH--SAAAKTITESVRRAL-------VINMRVHSFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFENASNHSKEPLPLTVKYHLRFSYTRRNYMWTQTGNFFLKETEGWHTTSLFP
LF-PSPGPREPASP--DGGEPGYIHEGFLAVQHAVDKAIMHYHANASAHQLFQKLT-VTA
KRFPFPPFISDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLIAVSCM
TVLFCVKVK-KD----VAVLSRSDPSLV----------------------------LVFL
LCFAISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLNQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWQNLLSPVNVDDDFCFGQVLGMLLLDSVFYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------LPSY-WCGNPRMVVGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKEKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAFIGGYEISQDMVQIRKSLGLCPQHDVLFDNLTVTE
HLYFYAQLKGLSRQK-CPEEVKQMLHILSLEDKRNSLCRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKNDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPKAISQ---LVYHHIPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGSL-
----IEEEHAMVQLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCITLAL
LAINYSSEV-----FDDPILRLSLSEYGRTIV---PFSAPGTSQ-------LYQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVAMSFRDEAERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSALQAAKDQ-FSE-----SRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERTVQAKHVQFVSGIRVATFWLSALLWDLISFLIP-----ILLLL--------
VVFRAFDVRAFTQDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------TRLT
IFNVLSG--------IATFLM---VTIMRIPALKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSKVATQ-------NCKKYNIEYQENFYAWSTP
GVGRF--VTSMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-WRRW---M--LAELHSRTSVVPEDLDV-----AQERSRVLTPSLDSL--LDTPLIIKEL
SKVYEQQ--APLIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSISSDIVKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGACVENTLRG
LLLE-PHANKLVRSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVQS-------EGQQ---DALEKFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHNLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLA
FNQFAVLLWKNVTL---KRRQLVNLILEISVVLVFGMVLLISRAVFK-IKGS--------
----------------------GPHNYTS--RSISDLPSFLENP--------DEWELIYV
PSN--IDVVKEISKNVKRNL-------NISIKVRGFSAEA-------DFENYIKYNYS-S
EKVLAAIVFE-DFKNSSDPLPLQVKYHLRFSYLQRTLQ--------WPDILGWKTALLFA
NR-PSLGHRNPNQS--DGGSPGYIKEGFLAVQYALDKAIMLYHESSAGQKLFDNIS-IFV
QRFPHPASSFDGLLWLSSPFFPVMFIFMFSPSILSILRLIVWEKENGLK-----------
----------------------------EYQLIIGLRNWIIWAAYFFTFLLLHIIIISLI
CVLFFT--KVID----KPIFYHSDYSSI----------------------------FVFF
MCYAIASIFFGFMVSTLFSKA---NLAASVGSFLFFATFFPFNVMIEYYGEITLARKLAS
CLSLNVALAMGINLLLKLEMK-EVGVKWNNLWTQALLDDNLIFGYMLGMLLFDAFLYG--
LVTWYIETVFPGPYGVPQPWY-FFL------MRSY-WFGSRGIREE-R--EERTRHGTTQ
NSDFEAEPADLVAGI-QMKH-LY-----KEYRDKVAVNDLSWNLYQ---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQISVLLGH-N
GAGKTT--TLSILTGLYPP-TRGKAYINGYDISKNIAQIRKNLGFCPQHDLLFNDLTLSE
HLFFYCMVKGVPRKM-HPIEIDHMLSAFNLLEKCDEFSQSLSEGMRRKLSVIIALIGGSK
---VVVILDEPSSGMDPVSRRATWDLLQKYKQNRTILLSTHYMDEADVLGDRIAIMVRGT
LQCCGSSVFLKQSYYGAGYHLVMEKKPHCDVEGITA---LIDSHIPDGSVD---NNTVTT
LSFFLPKDHTQRYE---STLFNDLDEKQEELGIARYGASITTMEEVFLK--VNKLAHSQM
DSQAL--QSPSLKDQN-KRQDKNENIDVTRNY------------------KRST------
--SASWDGLASIKFNTGLPLYCQ-QFHSMLIKRALFSWRNWKLTL-LQILVIVFVTTYLL
KSLSVK-------DKERSSREMDLGHYGRTIV---PYSISGNSS-------LALNIIKNL
EVFLKAKNQELRE-VQ-----GNVTDYI-----LQSKECRNFCIIAFSIKIEQNKTVFTV
LFNNEAYHSA-----------------------------ATSLAVLDNILFMSLSGPNAS
IAITNTPQPF--PLYGINI---V-----PTSGMQVALCLAFGMAVMA---------SS--
FCLQTVTEKIAKVKHIQFVSGVHVLTYWLSALLWDLICFSIP-----CCLIL--------
GVFKFLGLDAFVVDYHFLD-TMMIFMLYGWCVVPLMYLGSFLFSSSTVAF------VKLT
LFNYLTT--------LTSIIIHTVVQQYA---RDLPVSTKTTIFNTLMMLPGYNFAMCIS
KLFD-------------NYQMNK-RCSGKF--QSGFLD----CKKA--LEKKSIYSFEEH
GIAKF--LTTLA---------------AMGPFYLLLILYLDSSF-CSLKTLVFNKIMPN-
FSKMFIKSNKAIVSGR--VIEEFEDEDV-----RNESKKVLALSH--HSLRNTPLFLKKL
KKIYCKC--PVVKAVRNISLVVEK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

SE-CFGLLGLDGAGKTTIFKMLTGEESITSGVVLID
GINVTENIRQIRS-RISYCPQSDAMLNYMTGRELLIMYARL-WGVPEPDIYAYVEAFLHS
LQLE-TYADEFVYTY---SGGYKRRLSTAIALM---------GRPSVIFLDEPSTGMDPV
AQHLIRDTVTQICKTGKAIII--SSHSME----GCEALCT-----RLAIMVKGRFVCLGS
PQHLKNKFCNVYSLKAKVNM-------DMEK---SKLKEFKEFIART----F--------
-P-GNII-----NQEYQGILHYYIPKEDISWGKSKVFSILEDAKLLFSLEDYSFSQITLE
QIFLTFANIDKMK-----------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNLLT
LNQFAVLLWKNFTL---KRRQFFNLILEVLTALAFPMMLLLLRAVIH-ITVA--------
----------------------GPLFFKA--QSDHLLICFSLFTYKPFIS--TLCKLIYF
LSE-GIIICFYLS-----EQ-------FYFSVVQGFSSEI-------EFEKYIKYDYR-A
HKVLAAIVFDCDFKNRHDPLPLQVKYHLRFAAIQRTII--------WPDETGWKTTLLFP
NQ-PSVGPRNPGHQ--DGGGPGYIREGFLAIQHALDKAIILYHESSAR-QLFDDIS-ILV
QRFPYPAYPDDGLLLLTGSFLPLMFILMFSPTVLSIIRSIVWEKEKRLK-----------
----------------------------EYQLTIGLKSWMIWAAYFFTFFFFYIFIVSMI
CVLLFAKAS-PY----MAVTSNIDYSFI----------------------------FVFL
MCYAIASIFFGFMVSTFFNKA---RLAASAGSFIYFVSFFPFNSIAQYYGRINLTMKVAA
CLSPNIALALGIKLLVKFETK-QTGVNWNKIWTPATLEDNLTFGHMMGMLVIDAFLYG--
LVTWYIEAVFPGQYGMPQPWY-FFL------MHSY-WFSKPRIKIK-K--EEMNDSVITQ
NKYFEAEPTGLVAGI-KIKH-LYKKT--FELGDKVVINNMSLNLYK---GQITILLGQ-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 912)

TT--ALSILTGHYPP-TRGEVFIDGYDITKNITEIRENLGFCPQGDLLFNDLTLSE
HLFFYSMVKNIHQKM-SSNEINHILSTFDLLEKRDTFSKSLSGGTKRKLSIIIALLGGSK
---V-VILDEPSSGMDPFSRRATWDILQQFKHDRTILLTTHYMDEADILGDRIAIMVKGT
LQCCGSSIFLKKT-YGAGYHIVMEREPHCDLGKICA---IIESHIPDAILE---SYLGAE
LSFILPKEHAHRFE---A-LFNDLEMKKGELGVANFGASITTMEEVFLK--VNKLADSEM
EIQSI--QSS-LSTTQ-RGQNRNQSRRVLRNH------------------EGL-------
----RLNEIANIKFNTGFPLYHQ-QFHAMFLKRALFNWRSWKLTL-LHISIILFVTTYLL
TTLNL--------YYIMPAREMDLSQYGRTIV---PYSISGNSV-------LALNIINNL
EIFLKLKNQELQE-VQVNLKKGNVMKHI-----KESKEYRDFSLTAFSIEVEKNNTVFTI
FFNNEAYHSA-----------------------------ATSLAVFDNVLFMSLSGANAS
IKVSNKPQPL--PHYGSNIVFRR-----PTNGSQVVLCLAFGLAVVI---------GS--
FCLQTVTERATNAKHIQFVSGVYLLTYWLSALLWDLIYFSIA-----CCFLL--------
GVFIYCGLDAFVADFHFLD-TMMIFMLYGWSVVPLMYLGSLLFSSSTTAY------IKLT
LFNYFST--------VFSIVTHIVMKFYD---NDIPDFTKTLMNNILMVLPSYNFAMSIS
KFFD-------------DYEVKK-LCAKFEIE-ALQCR----EMEI--IKKNNVYSFGEH
GIANF--LISSA---------------ALGLIFLLLLFCLEISN-FNILRLRWVSTILR-
LENMF--TELASSLKL--FPQEYGDKDV-----INERKRVQKLLP---RLMAVPLLFNEL
TKTYYKC--PVVKAVRNISLLVPKYE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEEITTSGVVLID
GINITENIRKIRS-RIGYCPQSDPMLGHMTGREVLIMYARL-RGVPEPDIGMYVETFLYS
MHME-THADKLVCTY---SGGNKGKLNTAIALM---------GKSSVVFLDEPSTGMDPV
ARRHMWDTVTGICNSGKAIVI--SSHSME----ECEALCT-----RLAIMVKGKFKCLGS
PRHLKNKFGNIYTLTAKINI-------GDNE---DKLEQFKEFIETN----F--------
-P-GNII-----NQDHHGIIGYYIPSKGICWGK--VFHIMEEAKTLFNLVDYFISQITLE
QIFLTFANIDKPTSDYYA------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------LPAPEKMAA
LRQLALLLWKNYTL---QKRKVLVTALELLLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPE--QSIQELPLFFTFPP---PG--GTWELAYV
PSH--SDAARTITESARRAL-------LINMRVRGFPSDK-------HFEDYIRYDNR-S
SNVLAAVVFEHEFSHSTDPLPLAVKYHLRFSYTRRNYIWTQSGSFLLKETEGWHTTSLFP
LF-PNPGPREPSSP--DGGEPGYIREGFLAVQHAVDRAIMQYHANASAHQLFQKLT-VVV
KRFPYPPFIQDPFLVAIQYQLPLLLMLSFTYASLTIVRALVQEKQHKL------------
---------------------------KEYMRMLGLDSWLHWSAWFLVFFLVLLVVVSLM
TLLFCIRVK-KG----VAVLTSSDPSLV----------------------------LAFL
LCFAISSICFSFMVSTFFS-----------------------------------------
--------------------K-GTGIQWRDLLSPVSVDDDFCFGQVLGMLLLDSVLYG--
LVTWYVEAVFPGQFGMPQPWY-FFI------MPSY-WCASPRTATGKE--EDADPEKGIP
TEHCEAEPEALLPGI-KIKH-LSKVF-QVGHKDRAAVRDLSLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGQAYIRGYEISQDMACIRKSLGLCPQHDILFDNLTVAE
HLSFYAQLKGLSRHK-CPEEVKQMLHALGLEDKRHTRCKLLSGGMKRKLSIGIALIAGSK
---V-LMLDEPTSGMDAISRRAVWDLLQQQKTDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYHMTLVKEPHCNPASVMQ---LVYQHIPNATLQ---SNAGAE
LSFVLPKESTHRFE---S-LFGKLEKRQKELGIASFGASVTTMEEVFLR--VGKLVDSSM
DIQAV--QLPALQYQH-ERRASDWALDS---------------NLCGLL-DPTDGVGTL-
----IEEEPAMVKLNSGLALHWQ-QFWAMFLKKATYSWREWKMLA-AQVLVPLTVVTLAL
LAINYSSEI-----LDDPLLQLTLSEYGRTAV---PFSAPGASR-------LGQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVATSFRDVGERMVVTA
LFNNQAYHSP-----------------------------ATALTVADNLLFRLLCGPRAS
IVVSNYPQPRSALQAAKDQ-FSE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATYWLSALLWDLISFLVP-----SLLLL--------
AVFRAFDVRAFAWDGRAAD-TLLLLLLYGWAIIPLMYLLSCLFSSAATAY------TRLT
IVNILSG--------IATFLM---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
NLYE-------------NYETQR-YCTSSEIAAH-------YCKKYNIVYQENFYAWSAP
GVGRF--ATSMA---------------ASGCFYLSLLFLIETNLLQRLRSAVCAL-----
-RRRR---T--LAELCAQTALLPEDQDV-----ANERNRVLAPSPDPL--LDAPLVIKEL
SKVYDQR--TLLLAVDRISLAVQR

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGEESITAGDAFVG
GHSIRSDIGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGTCVENTLRG
LLLE-PHADKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAVII--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------KGQQ---EALEAFKAFVELT----F--------
-P-GSIL-----EDEHQGMVHYHLPSHGLGWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTSEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATRQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFI------LPSY-WCGKPRAVAGKEE-EDSDPEKELR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRYV---E-GLFANWKKQKRAAISQLWASITTHGEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEEHTAVKLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERMVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIENNLLQRLRGILCAF-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEDFKAFVDLT----F--------
-P-GSIL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYSVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

---------------------------------------------------------LSG
LNSFAVLLWKNFTL---KRRRFIALAVEILLMLLFAGILLMTRYFVG-AKDS--------
----------------------GPLRYPA--LPVSDVPEFLRSPT--LFQ--SPWRLAYL
PSR--SVVVKEIIEHVKNDL-------DIDFKVQGFSSES-------DFEEHLKYENN-S
KKMFAAVVFDHEFKDSNDPLPLQVKYYLRFSCLQR-NSTF----ANQFFVRSWNTAFLFP
WS-SSVGPRVKGDA--TGGAPGYIREGFLLLQHAVDKAIMLYHKNRATEELFDAVS-IFV
QRFPYPKYRRDFFFTFSGFFIPLIILFMFSMNHFTLIQSIVWEKENRLK-----------
----------------------------EYQLMIGLSNGMLWAAYFITFIFLYLIVILFM
CMTFFAKIE-P-----VPILQHSDPSLI----------------------------FIFL
LCFAIASIFFTFMVSTFFNKG---NIAVSFGGFLYFATYLPYTIISQSYPKMTVIQKLAS
CLSSNIAMALGTQLLVKAEAE-NIGIKWNNILSSTQT-DNFVFAYILGMLLFDAFLYG--
LVAWYIEAVFPGEYGVPKPWN-FFL------LHSY-WSGEPSEK--NK--EKIQFYESVQ
SQYFEDEPANLVAGI-QIKH-LCKAF-QVQNNIKIAVKNLSLNLFE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGQ-N
GAGKST--TLSILSGLYPP-TNGEAYINGYAISKDMVHIRKSLGLCPQQDLLFNYLTVSE
HLYFYCLIKGIPRKK-RPMEVDHMLSAFNLLEKRDAFSQSLSGGMKRKLSIIIALIGGSK
---V-VILDEPTSGMDPVSRRVTWDLLQQYKQDRTILLTTHYMDEADVLGDRIAIMVSGT
LQCCGSSVFLKQI-YGVGYHITMVKEPHCQVEEISQ---LIHYHIPTATLE---NNVGSE
LSFILPKEYTHRFK---V-LFTNLEERQKELGIESFGASITTMEEVFLR--VSNAADTQD
SQAIQ--T--PIQMMN-KVINKTQNVNSSTYF------------------ESVY------
--GSIFRENSTIVCNTGWSLYQQ-QFRAMFMKRAMFSWRNWKLVL-LQILGLLGVLTFLL
KAQDFS------NKNNEIVRQMNLRHYGQTIV---PLSISGNSN-------LTVNLLKHL
ENMLQSEEQILQK-VQ-----GDLLNYL-----MESKDCICSCIVAFSIEVKTNETVLTA
LFNNEAYHSP-----------------------------SASLMVLDNLLFKSVSGPDAS
LTVFNNPQPYHDKVVGNS-FFCR-----STNGDLVAFYVHFGMALLI---------SG--
FCLLTVTERVTNAKHIQFVSGIYVLIYWLSALLWDFIIFFIS-----CCLLL--------
GVFKYCRVDVLVMNYHFLD-TMMILMLYGWSAIPLMYLMSFLFSRSTTAY------IKLV
LFNYFSG--------IFSHYIDLTLTRLSQF---LLERIGLFLHYIFLLFVVHSLKNSLY
SFYE-------------N--LRS-TSHCSSS-LSKWYF----CSKFFLPFTGNVYSLEKN
MIGKY--LLAMG---------------TSGFVFLLLIFFGDVWW-WKLKTFLNQSFQ---
--RIWLLD---IVSKE--LSGKSEDEDV-----ENERKRILELPY---EYLNTTVLIKEL
TKIYFNC--PAVLAVKNISFTIQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTSTFQMLTGEITATSGDMFIE
GFSITNNILKVRS-RIGYCPQSDALLEYMTGREIMIMYARI-WGVSERQIHLYVNNWLNS
LHLE-SHADKLIHTY---SGGNKRRLSTVIALM---------GRPSVIFLDEPSTGMDPV
VRRLLWNLITQTRESGKAIIV--TSHSME----ECEVLCT-----RLAIMVKGKLMCLGS
PQHLKNKFGQLYILKVKVKP-------DMNK---DKLDDLKNFISTT----F--------
-P-GSVI-----NQETQRVINYYIPSKDNSWAK--VFGILEEAKEQFDLEDYSISQVTLE
QVFLTFAHPDKKDDFE--------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASLE
LKKLMILFWKNFTL---KRRKCVALVVEILIAVFFGLSLLGLRNVLI-LRKM--------
----------------------GPFSYTA--FPVNFVPSFIEAPV--TSP--YPWEL

PF12698 // ENSGT00760000118965_2_Domain_0 (178, 665)

AYV
PSK--STVVQNVVENVKKDL-------NTNMQVVGFSSER-------DFETYVKQINN-S
EKVLAAIVFDHDFQNSDDALPLNVKYYLRFSYFKKNKTQM----SN-SESDGWFTDSLFP
LF-S-LEPRNFKEL--DGGSPGYISEGFLLVQHALDKAIILYHSGAAAETLFNSVN-IFV
QRFPYPVQDIDVFYIIAIIFIPIVVAFIFSINHLTLVQSIVWEKENQLK-----------
----------------------------EFQLMIGLSHWMLWTAYFITFLFFYLFNIIFL
CFILFIKIE-P-----VPVFQYSDPSLV----------------------------FIFL
LLYAIAILFFSFMISTFFDRA---TVAVIFGGFIFLIIYIPSALLITDYKKMMFQRKLVS
CLSFNVAMALGFKFLVEAESM-KIGIKWSNIFSSTRP-DNFFFAYVMGMLLLDSFLYG--
VVAW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YIGAVFPGKYGMPKPWN-FFL------MRAY-WFGEQHTA--KN--ETIQYEETIQ
SQYFENEPTNLMAGI-QIKHLYKVIF-EENNTVKIA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 913)

LRDLSLNLYK---GQITVLLGP-N
GAGKST--TLSILSGLYPP-TSGKAYVNGYDISQDMDQIRKSFGICPQQNLLFDYLTVSE
HLYFFCRYLPFPQSYHILQEIGHMLSAFKLLEKQTAFSKSLSGGMKRKLAIIIALIGGSQ
---V-VIMDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1259)

SGMDPASRRATWDLLQSYKQGRTILLTTHYMDEADVLGDRIAIMVKGS
LKCCGSPMFLKRL-YGVGYHIVMVKAPHCDVEEISK---LIHHYVPTATLE---SNVGTE
LSFILPKEYTDRFE---V-LFTTLENRQAELGINDFGASVTTMEEVFLK--VSHMD-SQT
GLQAT--K--SPVQRS-QVPTPRQNTNMSNNA------------------ERPR------
--SLTEN---TTVFNTGCALYYQ-QFHAMFQKRLLFSRRNWKLIL-FQILGLLIPTAFLF
QDNDFQ------RINEETSRQMNLNEYGPTIV---PYSVSGNSN-------LSLSLSK

PF12698 // ENSGT00760000118965_2_Domain_2 (1259, 1717)

HL
ESMLTPKNHILRE-VQ-----GDLPKYL-----KENQECVVRCIVALSIEVKSNETVLTA
LFNNQAYHSP-----------------------------ALSLSVLDNMLFMSLSGAHAS
LTVSNKPQPVLQKK-------KK-----IIDGQDVAIKLQLGLALLI---------SG--
FCFLIVTERVSKAKHIQYLSGVSTLVYWFSALLHDFIIFFIC-----CCIILHSSCFYLT
TFYPYHKVEIFVMEYHFLE-TMLIFTLYGWSSIPLVYLMSFLFSESTSAY------IKLV
LFNYISG--------TYSILVE--HLLKTQ--TSMSNTTQALLSSTLLLFPNYNLVKCLS
DYTG-------------VYRVKM-LCAQ-KT-TQHLLN----CSKE--NTESSIYSLENH
MIGKC--LLIMG---------------VLGCVFLIFIFVWENAF-WRLRAFVHQHIYFG-
IYKKFKKV---SA-----------------------------------------------
-------------------------S-CYGFVWF--------------------------
-------CFSLLS

PF00005 // ENSGT00760000118965_2_Domain_3 (1874, 1974)

-RIGYCPQFDALLEYMTGWEIMIMYARV-WGVSEPQIPQYVNKHLTS
LELE-PHANNLISTY---SGGNKRRLSTAIAIM---------GKPSVIFLDEPSTGMDPV
ARRLLWNTVAKTRERGKAIII--TSHSME----ECEALCT-----KLAIMVKGKLMCLGS
PQHLKNKFGNIYILKAKVKS-------P------DKTENFKNFISVT----F--------
-P-GSIL-----KEENQGILTYSIPSKDNSWGK--VFGILERAKEEFSLEDYSIGQITLE
QVFLTFANPDK-------------------------------------------------
------------------------------------------------------------
---------------------------------------------

--------------------------------------MPSPGAPECPCFLREGLSECLC
FCLAAHQRTLLYLF---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDTAKTVTETVRRAL-------GINMRVHGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYLWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATRQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLVFFLFLLIASSFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GVGIQWQDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGQFGVPQPWY-FFF------MPSY-WCGKPRTVTGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNVYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDSLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHTLSLEDKWNSPSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKRDHTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPTDGIGAL-
----IEEERTTVMLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPVTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTIV---PFSIPGTSQ-------LGQQLSEHL
KNSLQAEEQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTV-TA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTWDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------TSGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLQRLRGIFCVF-----
-RRRQ---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSSDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHSISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIII--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQR-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGQNLSWAK--VFGILEKAKEKYSVDDYSVSQISLE
QVFLSFAHLQPSATEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELLLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYQG--QSIQQLPLFFSFPP---PG--DSWELAYI
PSH--SDAARTITETVKREL-------VINMRVHGFSSEK-------DFEDYIRYDNR-S
SNVLAAVVFEHTFNHSKDPLPLAVKYHLRFSYTRRNYMWTQTGNIFLRETEGWHTNSLFP
LF-PSPGPREPLSA--DGGEPGYIREGFLAVQHAVDKAIMHYHANASAHQLFQKLV-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLSIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFFLIMVAFM
TLLFCVKVK-KD----VAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYYFTFSPYYFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNTRTVVGKKE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKVGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TMSMLTGLFPP-TSGHAYIHGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQMLHILGLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAVWDLLQQQKNDRTILLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDG---------------NLCGVM-DPTNGIGAL-
----IEEDEALLKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCITLAL
LAINYTSEI-----LDDPLLKLSLNEYGRTVV---PFSVSGTSQ-------LDRQLSEHL
TDMLQAEGQEHRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDTGEQTLVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPRAS
IEISNYPQPRSTLQVAKDQ-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVRAKHVQFVSGVRVATFWLSALLWDLISFFIP-----SLLLL--------
VVFQAFDVHAFTRDGHLGD-LLLLLMLYGWAIIPLMYLMSFFFSAASTAY------ARLT
IFNILSG--------IATFII---VTIMRIPAVKLVELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETHR-YCTSSRVASQ-------YCKKYNIQYQENFYAWSTP
GVGKF--VTSMA---------------ASGCIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-QRRW---T--LAELQNRTSVLPEDQDV-----ADERSRVLVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLISACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---EVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQALPLFFNFPP---PR--GTWELAYI
PSH--SAAAKTITESVRRAL-------VINIRVHSFPSEK-------DFEDYIRYNNH-S
SNVLAAVVFENISSHSKEPLPLAVKYHLRFSYTRRNYMWTQTGNFFLKETEGWHTTSLFP
LF-PNPGPREPTSA--DGGEPGYIHEGFLAVQHAVDRAIMHYHANTSAHQLFQKLT-VIA
KRFPFPPFISDHFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLIAVSFM
TLLFCVKVK-KD----VAVLSSSDPSLV----------------------------LVFL
VCFAISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLNQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWQNLLSPVNVDDDFCFGQVIGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFL------LPSY-WCGNPRMVVGKEE-EDSDPEKVLR
TEYFEAEPENLVAGI-KIKH-LSKVF-QVGNKEKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYIGGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLCFYAQLKGLSHHK-CPEEVKQMLHILSLEDKRNSLCRFLSGGMKRRLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCDPKAISQ---LVYHHIPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASYGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGAL-
----IEQENVMVQLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEV-----FDDPILKLSLGEYGRTIV---PFSVPGTSR-------LDQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVAVSFRDVGEQTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSTLQAAKDQ-FSE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVRERAVWAKHVQFVSGIHVAAFWLSALLWDLISFLIP-----ILLLL--------
VVFRAFDVRAFTQDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------TRLT
ILNILSG--------IATFLI---VTIMRIPALKLEELS-RTLDQVFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSEVATH-------YCRKYNIKYQENFYAWSTP
GVGRF--VTSMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTLVYAF-----
-WRRW---T--LAELHSQTSVVPEDLDV-----AQERSRVLTPSLDSL--LDTPLIIKEL
SKVYEQQ--APLIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGACVENTLRG
LLLE-PHANKLVRSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARAREAGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGQL---EALEKFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHSLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLLT
LNQFAVLLWKNFTL---KRRQFINLIMEVLTALVFPVMLLLFRLLET-IKVV--------
----------------------GPFNFTS--HPISTLPYFLKNP--------EQWELIYV
PSD--IDVIKEITENVKRNL-------NISIKVKGFSSET-------EFEKYIKFDYG-S
RKVLAAIIFDYDFKNSSDPLPLQVKYHLRFVRIQRTVW--------WPDRVGWRTSLLFP
SR-PSVGPRNVDYQ--DGGSPGYLREGFLAVQHALDKAIMLYHESTARQKLFDGIS-IFV
QRFPYPAYPHDELIGITSNFFPLMFILMFSPTVLSIMRSVVWEREKGLK-----------
----------------------------EYQLIIGLRNWMIWAAYFFTFFLFYIIIIILI
CVLFFAKASIVG----DPIFRYSDYSFI----------------------------FIFL
MCYSIASIFFGFMISTFFSKA---RLTASAGNLLYFASFFPFNSLSQHYGQLTLTKKVAA
CLSSNVALALGVNLLLRLELK--LGAKWDNLWTPANLEDNLVFGYMLGMLLLDAFLYG--
FVTWYVETVFPGQYGVPQPWY-FFL------MHSY-WFGQPTTRRE-N--EEMKCCGRNE
DKYFQAEPPNLVAGI-QIKH-LH-----KEFGDKVAVNNLSLNLYK---GQITMLLGQ-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 912)

TT--TLSILAGMYLSLSRIEVYINGYDISKNIIEIRKNLSFCPQHDLLFNDLTVSE
HLFFYAVVKRLHRKV-YPMEINRLLSTFNLLEKRDTFSKSLSGGMKRKLSIIIALLGDSE
---V-VILDEPSSSMDPVSRRVIWDLLQENKHNRTILLTTHYMDEAEILGDRIAIMVKGT
LQCCGSSVFLKQI-YGAGYHIVLEREPHCDVEKVSA---MIQSHIPDATLE---NCTGAE
LSFILPKEYAHRFE---A-LFNDLEKTQKQLGIASFGASITTMEEVFLK--AHKLADSEK
DIQPI--KYPSLKSQK-LTQDMKWNVNMSSNY------------------ERPV------
--FSRLNEIATIKFNTGFPLYCQ-QFRSMFIKRALFSWRNWKLIL-LQTTVILIVTTYLL
LTTKL--------QYELPAREMDLSQYGRTIV---PYSISGNSE-------LAMNLTKNL
KIFLNAKNQELRE-VQ-----GNIVNYI-----LENKECHDFSIIALSIEVEKNETIFTI
LFNNEAYHSA-----------------------------ATSLAVLDNILFMSLSGPNAS
IEVYNKPQPP--HIYGSNV---V-----PTSGSQIVLCLAFGMAVVV---------SS--
FCLQTVTERTTNAKHIQFVSGVYILTYWLSALLWDLICFSIS-----CCLLL--------
GVFKYCGIDAFVADYHFLD-TMMIFMLYGWSVVPLMYLGSFLFSSSTTAY------VKLT
LFNYFST--------VFSMITYILWHLSE---NSFPDSIGASIENVLMVLPSYNFAMSIS
RFFD-------------DYEVKK-ICARKF--PTTSLH----CSKT--FTENNIYSFGEN
GIAKF--LISSA---------------AMGLFYLLLLLCMETTF-WRLKNFFFQKIIFN-
VYNILMKGRKAMVSIQ--VINELEDPDI-----ENERKKVLALPP---KLKNTPLLFKEL
TKIYYKC--PVVKAVRNISLVVKKSE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEETITSGVVLID
GISITENIRKVRS-RIGYCPQSDPMLNHMTGRELLIMYARL-RGVPEPDIYKYVETFLHS
MHLE-TQADKFVNIY---SRGNKRKLNTAIALM---------GNSSVVFLDEPSTGMDPV
ARHLLWDAVTWMCKSGKAIII--TSHSME----ECEALCT-----RLAIMVKGRFKCLGS
RQHLKNKFGNVYRLTAKINI-------DKNE---DKLGEFKNFIATA----F--------
-P-GNKE-----FQKHQGIVGYHIPGKEICWGK--MFSILEEAKVLFNLEDYSVSQITLE
HIFLSFANTDKTENEQEIKVV---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVVVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------GINMRVRGFPAEK-------AFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYLWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATHQLFQRLT-VAI
KRFPYPPFIADPFLVA

PF12698 // ENSGT00760000118965_2_Domain_0 (377, 665)

IQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLVFFLFLLIASSFM
TLLFCVKVK-PD----AAVLSRSDPSLV----------------------------LAFL
LCFAVSTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GVGIQWQDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFI------MPSY-WCGKPRTVTGKED-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDGLTVEE
HLYFYAQLKGLSRQK-CPEEVKEMLHTLGLDDKRDSPSRFLSGGTRRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKRDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPTDGIGAL-
----IEEEHTAVTLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPVTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSIPGTSR-------LGQQLSEHL
KDSLQAEEQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTV-TA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSDVAAH-------YCKKYDIQYQENFYAWSAP
GVGRF--VASMA---------------TSGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLQRLRGILCVF-----
-WRRR---T--LAELYTRMPVLPEDQDV-----VDERTRILAPSSDFL--LHTPLIIKEL
SKVYEQQ--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHSISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGQNLSWAK--VFGILEKAKEKYSVDDYSVSQISLE
QVFLSFAHLQPSATEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------YV
PSH--SAAAKTITESVRRAL-------VINMRVHGFPTEK-------DFEDYIRYDNH-S
SNVLAAVVFENASNHSKEPLPLTVKYHLRFSHTRRNYMWTQTGNFFLKETEGWHTTSLFP
LF-PSPGPREPASP--DGGEPGYIHEGFLAVQHAVDRAIMQYHANTSARQLFQKLT-VTA
KRFPFPPFI

PF12698 // ENSGT00760000118965_2_Domain_0 (370, 665)

SDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLIAVSFM
TLLFCVKVK-KD----VAVLSRSDPSLV----------------------------LVFL
LFFAISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GEFIQWQNLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTWYMEAVFPGQFGVPQPWY-FFL------LVSP-NAPVQ-------------------
---------------------------------------VELPLWR---AEVSL------
------------------------------------------------------------
-----------TFNA-C-------------------------------------------
------------------------------------------------------------
--------------MGPGWKTLLNFGVFCLAPGL--------------------------
----FPPTS----------------------------------GHNCSL--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGTL-
----IEEEHAVVQLNTGLALHCQ-QFWAMFLKKATYSWREWKMVA-AQILVPLTCVTLAL
LAINYSSEV-----FDDPILKLSLSEYGRTIV---PFSVPGTSQ-------LDQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVAVSFRDEVERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSALQAAKDQ-FSE-----YVRPLLIPQAPT--------------------
-PVLT--TRGAYC---Q---------------QLDTTHQATS-----SVLLQ--------

PF12698 // ENSGT00760000118965_2_Domain_2 (1501, 1718)

VVFRAFDVRAFIQDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------TRLT
IFNILSG--------IATFLM---VTIMRIPALKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSDVATH-------YCKKYNIEYQENFYAWSMP
GVGRF--VASMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-WRRW---M--LAELHSRTSVVPEDLDV-----AQERNRVLTPGLDSL--LDTPXIIKEL
SKVYEQQ--TPLIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGACVENTLRG
LLLE-PHANKLVRSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHRY--------------------------------
------------------------------------------------------------
-------------------------------------------------------QISLE
QVFLSFAHLQPPTSEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNLLW
LNQFAVLLWKNFVL---KKRKVISL

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

IVEIFMTLFFSGLILLHRRDVK-KEFQ--------
----------------------NVTIYRS--LFVLFPPPFLYN-----RS--VVYEVAYV
PSH--SDVAKNITETVIMKL-------RLNISVRGFSSEA-------EFEKYVEFEKKPE
VRVLAAIVFDHDFKNRHDSLPLKVKYHLRLGAGTERPS--A--LQS--FVNGWNTHLLFP
NT-PSLGPRNPFED--DGGSPRYIREGFLIFQYAVDQAIMMYHNGRRIETIFGDFF-IRI
RRFPYPAYYKDDFLWLFLSLFPLVVILVFSLTELTLIRTIVSEKEKRLK-----------
----------------------------EYQLMIGLSNAMLWASYFVSFFLMFVIITCLL
CMILFVKIV-P-----EVVFQYSDPSLV----------------------------FVFF
LCFVVSSISFGFLISTLFNTA---TLAVSFGGFFYFVTFFLYVFVSTAYEYMTLTEKLAF
CLCSNVAVALGIDFICRMEMK-QYGVQWDNILSPVNPHDSLIFAHIMGMLLFDAFLYG--
LMTW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YIDAVFPGKYGVPKPWY-FFV------QKSY-WFN-KALSIKK---EERQITDMIK
SDYFEDEPVDLVVGI-RIQN-LYKEF-TTERDTILA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 913)

VKNLSFNVYE---GQITVLLGP-N
GAGKTT--TMSILTGLTLP-TSGKVYINGYDISKDMNHVRNNLGFCPQDDILFAELTVSE
HLYFYCVIKGVPPEI-RPTEVNKMLTSFGLLEKHDAIAKSLSGGMKRKLSIIIALIGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1237)

SGMDPVSRRFTWNVLQQYKHDRTILLTTHHMDEADVLGDRIAIMVKGS
LCCCGSSIFLKRI-YGVGYHIIIVKEPHCDVEQITR---LVEQHVPDARLE---TNVAAE
LSFILPKKHTDRFT---G-LLTDLEKSQEKLGIGSFGVSITTMEEVFLN--KMNVNNFRK
NNEA-F-QTLSLKDKNRRENMNQ-NMNVPRSF------------------ER--SYS---
--PT-SSEHSNIMFNTGWSLNCQ-QFYAMFIKRAMFSWRNWSLIL-MQILGFLGIVYFLM
KGIEII------RTKTEPAREMDLEQYGQTIV---P

PF12698 // ENSGT00760000118965_2_Domain_2 (1237, 1719)

LSIAVDSD-------FTRNLTKNL
EILLKAKKQKLQE-VK-----GDLTEYL-----GQSQECIYSCIIALSFQPTRRQTEVTI
WFNNQAYHSP-----------------------------PLSLTVLDNIIFMALSGPNAS
ITVSNKPQPLNAASKKL---EKR-----KLTGAQVALNLFFGMSIFV---------SS--
FCLLTVTERITKAKHIQFVSGVSATNFWLSALLWDFLIFFIA-----CCLLM--------
MVFLLSGLDALTKNYRFLD-TLFIFMLFGWAVIPFTYLISFLFSSHTSAY------IKLV
MFQYCAG--------VFSVILNVIVTEI----SG-QKPSESLLLNSLMVIPIHNFGMSIS
KYYD-------------NQETKI-VCSSA-N-IPAFVN----CSKTSV-TEMNVYSLEDD
AIGRY--LIAMA---------------VTGFIFFLLIF

ENSGT00760000118965_2_Linker_2_3 (1719, 1816)

LLETTS-WKVRTFVYRYIFFE-
IYKKFNKD---RVSKE--LSGESEDDDV-----QHERNRILEQPR---ELLNFTVLIKEL
TKIYFTY--PAVLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLGIQKKE-CFGLLGLNGAGKTTTFEILTGEETATSGDVFIE
NLSITNNLLEVRS-KIGYCPQFDALLDYMTARELMVMYARL-WGVPETQITQYVNKLLQS
LNLE-PYADKFIYTY---SGGNKRRLSNAIALM---------GKPSVIFLDEPSTGMDPE
ARRLLWNRVTRARESDKVIII--TSHSME----ECDALCT-----RLAIMVKGKIMCLGS
PQHLKNKFGNVYTLKAKFKI-------DTDE---KTLEDFKKYIATV----F--------
-P-GSEL-----KHENQGILNYYIPSKDNGWGK--VFGILEEANKKFHLEDYSISQITLE
EVFMTFAKQEN-------------------------------------------------
------------------------------------------------------------
---------------------------------------------

--------------------------------------------------LCTPSSKMAA
PRQLALLLWKNYTL---QXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------
----------------------XXXXXXX--XXXXXXXXXXXXXX---XX--XXXXXXXX
XXX--XXXXXXXXXXXXXXX-------XXXXXXRGFPSER-------DFEDYIKYDNG-S
SNVLAAVVFEHAFNHSRDPLPLAVRYHLRFSYTRRNYMWTKAGSFFLKETQGWHTTSLFP
LF-PTLGPREPAAA--DGGEPGYIREGFLAVQHAVDRAIMQYHANTSAHQLLEKVT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLSIIRAVVREKERKL------------
---------------------------KEYMRMMGLSSGLH-SAWFIMTFLLLLIDSAFM
TLLFCVKVK-KD----VAVLTHSDPSLV----------------------------LVFL
LCFSISSISFSFMVSTFFS-----------------------------------------
--------------------K-GTGLQWRNLLTPVNVDDDFSFGQVLGMLLLDSVLYG--
LVAWYVEAVFPGQFGVPQPWY-FFL------LPSY-WCGSPRTALAKED-EDKDPEKALR
SEFFEAEPEDLVAGI-KIKH-LSKVY-RVGSKGKTAVKDLNLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 900)

GQITVLLGH-N
GAGKTT--TLSMLTGLSPP-SSRHASICRYEISQDMPRIRESLELCPQHDVLFDDLTVAE
HLYFYAQLKGLSLHK-CWEEVRRMLRILDLEDKQDAPSKFLSGGMKRKLSIGIALIGGSK
---X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXAGYHMTLVKEPHCKPEAIAR---LVHQHVPSATLE---SNAGAE
LSFILPKESTHXXX---X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VGKLVDTSM
DIQAI--QLPPLQYQH-ERRASDWAVDN---------------HLCGVM-DPSNGTGAL-
----MEDDCASVQLNTGLALHCQ-QFRAMLVKKAAYSWREWKVAA-AQVLVPLTCLTLAL
LAINYSSEI-----LDDPSLELTLGPYGRTVV---AFSAARTSR-------LGQQLSEHL
RDLLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTAVTA
LFNNQAYHSP-----------------------------AAALALVDNMLFRTLCGPQAS
ITVSNXXXXXXXXXXXXXX-XXX-----XXXXXXXXXXXXXXXXXXX---------XX--
XXXXXXXXXXXXXXXXXXXXXXXXAAFWLPALLWDLTIFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHEAD-ALALLLLYGWAIVPLMYLLSFLFSGPATAY------TRLT
IFNVLSG--------VATFLV---VTIMRIPAVKLEELS-RTLDYVFLVLPNHCLGMVVS
SFYE-------------NYETRR-YCTSSDVATY-------YCHKYHIEYQENFYAWQAP
GVGKF--VISMA---------------ISGFVCLLLLFLLETSLLWRLRGLLCAA-----
-RRRH---A--LTEAYGRAPVPPEDQDV-----ADERSRVLAPTLDPP-PRDPPLIIREL
SKVYFTE--VPLLAVNKVSFAVHA

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

QE-CFGLLGINGAGKTSIFKILTGEEFATSGDAFVQ
GSSINSDLGEXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXX-XXXGGNKRKLSTGIALI---------GDPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVHS------DDGQK---AALDEFKAFVSLT----F--------
-P-GAIL-----EDEHQGLVHYHLPAQSLSWAK--VFGVLERAKEKYGVGDYSVSQISLE
QVFLSFAHLQPPAEDEGQ------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------

PF00005 // ENSGT00760000118965_2_Domain_1 (792, 959)

LILGLTPP-TSGKVYISGYDTSKDMVHIRNNLGFCPQDDILFSELTVSE
HLYFYCVIKGVPPEI-RPTEVSKMLTSFGLLEKHDALAKSLSGGMKRKLSIIIALVGGSK
---V-VILDEPTSGMDPVSRRFTWNVLQQYKHDRTILLTTHHMDEADVLGDRIAIMVKGS
LKCCGSSVFLKRI-YGVGYHIIMVKEPHCNVEGITQ---VVDQHIPDARLE---SNVAAE
LSFILPKEYTHRFK---D-LLTDLENRQTELGIGSFGVSITTMEEVFLS--KINVNNFKR
EDED-F-QTPSLKDKNRRENMNQ-NMNAPRNF------------------ER--AYS---
--PT-TSEPSNIRFNTGWSLNCQ-QFYAMFLKRAMFSWRNWNMML-MQILGLLGIVYFLM
KAMQIS------RTRVETSREMDLEQYGQTIV---PFSDDDRSN-------FSQNLTKIL
EIMLKAKKQKLQE-VK-----GDLTKHL-----AKSEECIYSCIIALSFHADRNQRIVTL
WFNNKAYHSP-----------------------------PLSLAVLDNIIFMALSGPDAS
ITVSNKPQPQNIVSKKL---ESR-----TMTGMQVALNLFFGVSIFV---------SG--
FCLLTVTERITKAKHIQFVSGVSPINFWLSALLWDFIIFFIA-----CCLLM--------
VVFLSSGLDALTKNYRFLD-TLVIFMLFGWSVIPFTYLISFLFSSHTSAY------IKLV
MLNYCAG--------VFSIGMDVIITIT----SG--PGSESLLLNSLMVLPIHNFGMSIT
KYYD-------------NQETKI-LCSSA-N-VPAFIN----CSKTSV-TQMNVYSLESD
AIGRF--LIAMA---------------VTGFVFFLLIFLLETTL-WKVRTFVFRYIFFG-
VYKKLNKD---IVSKE--LSGESEDDDV-----QYERNRILEQPR---ELLNDTVLIKEL
TKIYFTC--PAVLAVRNISLGIQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

EE-CFGLLGLNGAGKTTTFEILTGEETATSGDVFIE
NLSITKNLQEVRS-KIGYCPQFDALLDYMTAREIIIMYARL-WGIPETQITQYVNELLQS
LNLE-PYADKFIYSY---SGGNKRRLSNAIALM---------GKPSVIFLDEPSTGMDPG
ARRLLWNTVTRARESGKVIII--TSHSME----ECDALCT-----RLAIMVKGKFKCLGS
PQHLKNKFGNVYILKIKFNM-------DTDE---NKLEDFKKYIATV----F--------
-P-GSEL-----KHENQGILNYYIPRKDNGWGK--VFGILEEAKEQFNLEDYSISQITLE
QVFLTFATPEN-------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
FKKLKLLLWKNFIL---KKRKTLITL

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 664)

LEILMPLIFSAIVLYLRFNSM-SKHV--------
----------------------ASTNYQT--VDISLLPVYFYNYP---LK--SKFQLVYI
PSK--SETLKAVTEMVEQTF-------AVDFEVLGFPSVP-------LFENYIIKDPK-S
FYILVGIVFDHSFNSSNEPLPLVVKYDLRFSYVQRNFAPSLKHLFFPDEIEGWCTAFLYP
PN-LSQEPREFVYA--DGGNPGYNKEGFLAIQHAVDKAIMRHHAPNATLNMFKNLR-VLL
QRFPLGPHIRDPFLMILQNEFPLLLVLNFICVELIVINSILLEKEKKLK-----------
----------------------------EYMCMMGLESWLHWVAWFITFFISVLIAVSVM
TILLCTKVN-N-----VAVFRNSNPTLI----------------------------FIFL
MCFATATIFFAFMMSTFFQRA---HVGTVISGIVFFLTYLPYLYITFSYHQRTYVQKIAF
CLFSNVAMAIGVRFISLFEAK-GTGIQWRNIG---SVQGDFSFAQVLLLLLWDSLLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 757)

FMVESVFSGKFAIPKFWY-FLA-------------KKNAPVALPL-LDIGDPERPSR
REFMQDGPPDQMKAI-EIQH-LYKVF-YRGRSKCIA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 913)

VKDVSMNLYK---GQITVLLGH-N
GAGKTT--ICSILTGLISP-SKGQAYVHGYEVSKDMVQIRKNLGWCPQHDILFDNFTVTD
HLSFYGQLKGLSHQK-CCEEIEELLHLLSLKDKRNCRSRSLSCGMKRKLSLGIALIADSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1184)

SGMDSTSRRAIWDILQQQKSDHTILLTTHFMDEADLLGDCIAIVSKGE
LQCCGSPPFLKQK-YGAGYYMTLIKTPLCDTTKLSS---VVYHHIPNAVLE---SSIGEE
MIFILPKKNIPSFE---A-LFTDLEQRQIELGISTLGASVTTMEEVFIR--VCKLADSTA
NILTE--KRPSIHPHP-R-------IH--RVPVDR-------IK--YLHSRI--------
--FSMQ-TDLPIKPNTGLCLLCQ-QFYAMLLKKVTYSWRNRML

PF12698 // ENSGT00760000118965_2_Domain_2 (1184, 1718)

MLFVQILLPLLIIMLSL
TFFDFKLNK---M--KNVPLELTLKTYGQTIV---PFFVSENSH-------LDPQLADNF
INLLVAAGQIPLR-VR-----SRVEDFLLKKSKDAPEDFDKLYVVAVSFEDVTNHTTVKA
LFNNQAYHSP-----------------------------GMALALVDNFLFKLLSGANAS
ITTTNYPQPQTAEELSESI-LYQ-----GPKGHYLVINFLFGIAFLS---------SS--
FCILTVTEKNIKSKHMQFVSGVSAVAFWLSALLWDLISFLVP-----TLLLV--------
LLFLWYKEEAFAHHENTPA-VVWIMMLYGWAVIPFIYTVSFSFKTPGNAC------VKLV
IMLTFLS--------ISPN--VL-VTVTSDKDLGYAELS-NSLDHMFLILPGHCLGMAFS
NLYY-------------NFELKK-FCSAKNLSDIDCNDV-----SEGYVVQENIYAWESL
GIGKY--LTALA---------------ILGPVYITLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIEANTFCILKSK-LCG-FSR-
--KEN---ME--M-FLD--EMEDE--DV-----LEEAETIKFGFETLI--QKTPLIVKEV
SKVY-NK-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFTVKEKE-CFGLLGLNGAGKTSIFNMMTGEQPITSGDVFVK
GFNIKSDLVKVRH-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPERHIKTCIDQIIED
LLMR-VYADKLVKTY---SGGNKRMLSTAIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQARVQR-------ELQQ---EVLKKFKEFVEMT----F--------
-P-GSNL-----EDEHRGMVQYYLPDHNLSWAK--VFSIMEQAKNDYMLEDYSINQVSLE
DIFLSFTSPMFSTKGKLQQGQVVLASPLSPS---LSKPILLSP-SHSSSQPPIPPP----
SEPVRL------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFPSEK-------DFEDYIRYDNC-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMEYHADAATRQLFQRLT-VTI
KRFPYPPFI

PF12698 // ENSGT00760000118965_2_Domain_0 (370, 665)

ADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PN----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFI------MPSY-WCGKPRAVAGKEE-EDSDPEKALR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEDISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEERTAVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVNA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVASFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFLGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLQRLRGILCAL-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRLSLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIII--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYGVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
FKKLKLLLWKNFVL---KKRKTLITVLEILMPLLFSAIVLYLRFNSM-PKHV--------
----------------------STTKYPA--FDISFLPIYFNYYP---TR--NKYQLAYI
PSK--SETLKTVTEMVDQAF-------TVGFEVVGFPSVP-------LFENYIIKDPK-S
FFILVGIVFDHSFNSSNEPLPLMVKYDLRFSYVQRNFAQRR-HFIFQEEIEGWCTAFLYP
PN-LSQEPREFAYA--DGGSPGYNGEGFLSIQHAVDRAIMRHHAPNATQNMFKDLK-VLL
QRFPFGPHIQDPFLVILQNEF

PF12698 // ENSGT00760000118965_2_Domain_0 (382, 664)

PLLLMLSFICVELIIISSIALEKERKVK-----------
----------------------------EYMCLMGLESWLHWVAWFITFFISALIAVSVM
TILFCTKIN-S-----VAVFGNSNPCLI----------------------------FIFL
MCFATATIFFAFMMSTFFQRA---HVGTVMGGIIFFFTYLPYLYITFSYHQRTYVEKIAS
CLFSNVAMAMGVRFISLFEAK-GSGIQWRNIG---SVRGDFSFLQVLLMLLLDSLLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVESPFLRKFRTPKSWY-LLA-------------KRPVPVTLPL-LDMGDPEKPSR
REFMQDEPTEQIKSV-EILH-LYKVF-YRGRSKRIAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYK---GQITVLLGH-N
GAGKTT--VCSILTGLISP-SKGQAYVHGRNISTDMVYIRKNLGWCPQHDILFDNFTVAD
HLSFYGQLKGLSPQN-CRGEIEELLPLLGLKDKWNSRSKFLTWGMKRKLSLGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1183)

SGMDSTSRRAIWDLLQQQKSNRTILLTTHFMDEADLLGDRIAIMAKGE
LRCCGSPAFLKQK-YGGGYYMTLIKMPICDTVKLSS---VVYQHIPNAILE---SSIGEE
VVFILPKKTMSRFE---A-LFTELEQRQIELGISTLGASVTTMEEVFIQ--VCKSADSGT
SVLTE--KRPSVQHCP-R-------IH--RVPVDR-------IK--CLHSRI--------
--FSVQ-SGLSIKLNTGLCLFCQ-QFYAMLLKKVTYSWRNWK

PF12698 // ENSGT00760000118965_2_Domain_2 (1183, 1718)

LMLFVQILLPLVIIMLSL
TFFDFKLKK---M--ENVPLELTLKTYGQTIV---PFFVSENFH-------LDPQLSDNF
KKMLVAAGQIPLH-LQ-----GPVEDFLLKKAKSSPEDFDKRYVVAASFEDVNNRSTVKA
LFNNQAYHSP-----------------------------GLALALVDNFLFKLLSGANAS
ITTTNYPQPQTAKELSESI-LYQ-----GPKGHYLVVNFLFGIAFLS---------SS--
FSILTVTEENTKSKHIQFVSGVSAAAFWLSALLWDLLSFLVP-----TLVLV--------
LVFLWYKEEAFAHYEGTAA-VVLIMMLYGWAAIPFVYTVSFSFKNPGNAC------AKLV
VMLTFLS--------ICPT--VL-VTVTSDKDLGYAELS-DSLDHVFLILPGHCLGMAFS
NLYY-------------NFELKK-FCDARNLSDIKCNDV-----YEGYVVQRNIYAWESL
GIGKY--LTALA---------------VLGPVYIILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIEANAFCKLRSR-LSR-FVR-
--KEE---LG--I-FLDVTEPEDEDGDI-----LDEAETIKFYFETLL--KKNPLIVKEV
SKVY-KG-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFTVEEKE-CFGLLGLNGAGKTSIFNMLTGEQPITSGDVFVK
GCNVKSDLAKVRQ-YIGYCPEFDALLNFMTGREILVMYARI-RGIPERHIKICVDQILED
LLLH-VYADKLVKTY---SGGNKRMLSTGIALI---------GEPAVILLDEPSTGMDPV
ARRLLWDTVARAREYGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKH---EVLEEFKAFVDLT----F--------
-P-GSNL-----EDKHEGMVQYYLPGHGLTWAK--VFGIMEQAKKDYMLEDYSISQVSLE
DIFLSFTSPVSSTKGQFQQGQAVLASPSPPS---HSSPSYQPP----------PPPSPPP
LEPVPL------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQALPLFFNFPP---PR--GTWELAYI
PSH--SAAAKTITESVRRAL-------VINIRVHSFPSEK-------DFEDYIRYNNH-S
SNVLAAVVFENISSHSKEPLPL-VKYHLRFSYTRRNYMWTQTGNFFLKETEGWHTTSLFP
LF-PNPGPREPTSA--DGGEPGYIHEGFLAVQHAVDRAIMHYHANTSAHQLFQKLT-VIA
KRFPFPPFISDHFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLIAVSFM
TLLFCVKVK-KD----VAVLSSSDPSLV----------------------------LVFL
VCFAISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLNQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWQNLLSPVNVDDDFCFGQVIGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFL------LPSY-WCGNPRMV----E-EDSDPEKKVL
TEYFEAEPENLVAGI-KIKH-LSKVF-QVGNKEKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYIGGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLCFYAQLKGLSHHK-CPEEVKQMLHILSLEDKRNSLCRFLSGGMKRRLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1422)

SGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCDPKAISQ---LVYHHIPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASYGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGAL-
----IEQENVMVQLNTGLALHCQ-QFWAMFLKKATYSWREWKMVA-AQILVPLTCVTLAL
LAINYSSEV-----FDDPILKLSLGEYGRTIV---PFSVPGTSR-------LGQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVAVSFRDVGEQTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSTLQAAKDQ-FSE-----GRKGFDIALNLLF

PF12698 // ENSGT00760000118965_2_Domain_2 (1422, 1718)

AM-----------------
--------------HVQFVSGIHVAAFWLSALLWDLISFLIP-----ILLLL--------
VVFRAFDVRAFTQDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------TRLT
ILNILSG--------IATFLI---VTIMRIPALKLEELS-RTLDQVFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSEVATH-------YCRKYNIKYQENFYAWSTP
GVGRF--VTSMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTLVYAF-----
-WRRW---T--LAELHSQTSVVPEDLDV-----AQERSRVLTPSLDSL--LDTPLIIKEL
SKVYEQQ--APLIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGACVENTLRG
LLLE-PHANKLVRSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARAREAGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGQL---EALEKFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHSLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MSSSW
PMQFSALLWKNFLL---KRRQIVGLAVEILFIFLFFAMILTLRSNAK-KQFR--------
----------------------NASTFNP--LPVE-LPNFLVN-----TP--HKYELVYV
PSK--SEVAKNIIEMVKKDL-------NVNFKVQGFASEK-------EFESYIKREK--S
ARVLAAVVFDHDFKNDQDGLPLQVTYHLRFSNYSSVPA--------SRQSEGWKTSFLFP
RI-PTLGPRNPNKS--DGGDPWYLNRGFLVVQRSLDKAIMSYHNDKA-EALMAGLQ-IFA
RRFPYPEYYHDDHMWSFISLFPWIILFVFSHNLFTLVRSIVSEKENRLK-----------
----------------------------EYQLMIGLSNGMLWASYFVTYLMLYLIIITLL
CAVLFFKIV-H-----ERILQHSDPSVV----------------------------TVFF
LLYVISLILFGFMISTFFTNA---SLAVAITGFFYFLTFFPQVIIIDQYAVMSLTQKVSA
CLIANIALAIGIDLLCKMEMK-GDGLQWNNLSSPVTPGDTFTLAHVFGMLLFDACLYG--
LVAWYVEAVFPGEYGVPKPWY-FFV------QKSY-WFGNPV--KKME--EDNELSSFVE
NEYFEAEPVGLVAGI-QIHH-LRKEF-KLHKTTFVAIKDLTLNFYE---GQITVLLGP-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTGFYLP-TRGKIYISGYDISKDMVQVRKNLGLCPQYDLLFPNMTVSE
HLLFYCVIKGVPPQR-RSVEINKMLTSFGLLHKRDEFSKSLSGGMKRKLSIIIALIGGSK
---V-VILDEPTSGMDPVSRRSTWNVLQQFKEDRTILLTTHHMDEADVLGDRIAIMVKGT
LQCCGSSIFLKKR-YGVGYHLVIVKKLDCDVKRVSN---LIIYYVPTASLE---NDVAAE
LSFLLPKEYTHRFE---A-LFAELEERQEELGIAAFGVSMTTLEEVFFA--NDNLKDWKL
NTINSAQPCPAVLLTPQSSRYRNLNMNAPRNF------------------ERTRR-----
--DTLRQSTETIQLNRGVSIFTK-NLMLICIYLKITNK--------QNLPQFLKLVYFLM
SGVTIV-------RHEEPARKMDLEQYGETIV---PYSITGNSP-------FAVDFLKVL
EDMLKAKKQKLQE-VQ-----GKQKRIL-----SKNRQCTHSCIIGLSIEIAGGAIKLTF
WFNNEAYHSP-----------------------------SLSLAVLDNAIFKSLSGSAAS
ITVFNKPQPRYVSNSAS---NSR-----RTSGIQIALNLFFGLSILI---------SS--
FCLLTVTERITKAKHIQFLSGVYVFIFWFSSLIWDIAILFFA-----CCLLL--------
VVFLLAGLDLLISDYHFLD-TMFIFMMFAWSVIPFIYLTCFLFSSGTSAY------IKLF
MFNQCMG--------FLGVLVDLLLNTL----QGVNTTVKNLILNILLLLPIYNLGMSIT
KYYD-------------FQENIH-LCSSSNN-IPKIIN----CDEL--VAARDVFSVNEN
TIGRY--IIAMA---------------ATGFAYFILILFMDTYA-WILRTFVTQYIFFG-
IYKKLNKKMQGTVSRE--LSGESEDEDV-----EDERDRVLGQPL---KFLDATVIIREL
IKIYFKF--PAVLAVRNISLAIKNEE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFQILTGEDSATSGDVYIK
GFSITKNNIKIRS-KVGYCPQFDALLEYMTAREILTMYARL-WGVPERRISYYVRKLLEL
LNLE-SHADKFIYTYRPPSGGNKRRLSTAIAIM---------GKPSVIFLDEPSTGMDPV
ARRLLWNVVTQIRESGKVIII--TSHSME----ECDALCT-----RLAIMVRGKFVCLGS
PQHLKNKFGNIYTVNVKFKA-------DTNK---DTIDDFKAFIYDV----F--------
-P-GSEL-----KQEGQGFLNYYIPSKKNSWGK--VFGVLEKAKEQFNLEDYSISQITLE
QVFLTFANPDKRADVR--------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------V

PF00005 // ENSGT00760000118965_2_Domain_1 (837, 959)

SVLN
LLPFVWQLKGYPASK-CPEEINHILRILNLEDKRHSLTKALSGGMKRKLSIGIALIGDSK
---V-VMLDEPTSGMDPASRRATWDLLQQQRSNRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKRK-YGAGYHMVMVKEPYCNLGEISR---LICQYVPNATME---SNAGAE
LSFILPKESTHRFE---A-LFTELELKREELGIAS-GASVTTMEEVFLE--VGKLVDSSM
DIQAI--QLPALQYQH-ERRSNDWAMDDSS-------------SLSGMT-DMTDDSGAL-
----ITEDCSSIKLNTGFYLCCQ-QFYAMFMKRAMYSWRNWKMVA-AQFLVPLIFTAFAL
IVAKTFPGP-----RDSSMLRLTLEPYGQTIV---PFSVPTASG-------LPQKLAEQY
VELLDAQHQSPLE-VP-----GGLEEYLISRASEEGGAFNEHYIAAASFEGVDNHTVVTA
LFNNQAYHSP-----------------------------ATALMLADNAVFRVLMGPNAS
ITVTNYPQPRNITEKAKDQ-LME-----GQTGFAIAINLLYGMASLA---------ST--
FALLLVSERAIKAKHVQFVSGVYVVNFWLSALLWDIINFLIP-----CALML--------
VIFQAFDVQAFTQDSHLVD-VMLIFLLYGWAIIPLMYLLSFFFSVAATAY------TRLT
IFNILSG--------TATFLA---VTIMSIPELGLVDLS-RTLDKIFLTLPNYCLGQCIS
DFYQ-------------NYEFIQ-FCTSSVEAIF-------ICKAFNISYQVNYFSWESP
GIGRY--LTSLT---------------IQGFSFLFLLFLIETNLLWRLKTLVCGI-----
-CRRR---R--WVALLNSVSVLPEDRDV-----ADERKKVLESPPELLSSLSSPLVIKEL
TKVYDSR--ESLLAVDRISLAVSK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGDESITSGDAFVD
GHSILANIKKVQQ-RIGYCPQFDALLEHMTGRETLSMYARL-RGIPERYIGSCVENMLRG
LLLE-PHADKLVRTY---SGGNKRKLSAGIALI---------GGPPVIFLDEPSTGMDPV
ARRLLWDAVTRTRECGKSIIF--TSHSME----ECEALCT-----RLAIMVNGQFKCLGS
PQHLKSKFGSGYTLLAKTRTD--------EE---GELQAFKAFVEKT----F--------
-P-GSVL-----KHEHQGMVHYHLTNKNLSWAQ--VFGALEKAKEKYRLEDYSVSQISLE
QVFMSFTRFQHYTEDRGK------------------------------------------
------------------------------------------------------------
---------------------------------------------

--------------------------------------------------------TMAV
LRQLRLLLWKNFTL---QRRKVLVTVLELVLPLLFSGILIWLRLKI--------------
-------------QSENV-PS-ATV-YPRQ-DIQSL-PLFFS-FP---PP-GGAWE-LVY
I-PDRN-A-------------AVQGVADSVRQTLGLNLRXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXVRYHLRFSSTRRNYMWTQAGSHFLRDAEGWHTTSLFP
LF-PSLGPREPAAP--DGGEPGYILEGFLAVQHAVDRAIMEQHANASARRLLSSLT-VKV
QRFPYPPFLSDPFLVAVQYQLPLLLMLSFTYTALTVIRAVVQEKEQRLK-----------
----------------------------EYMRVMGLGSWLHWSAWFLLFFLFLLLIVSFM
TLLFCVKVK-KD----VAVLAHSDPSLV----------------------------LVFL
ACFAVSTIAFSLMVSSFFSRX---------------------------------------
-----------------------XGVKWNNLWTQVSLEDNIIFGYLIGMLLLDAVLYG--
LITWFIDTTFRRNYGSHQPWY-SFL------MXXX-XXXXXXXXXX----XXXXXXXXXX
XXXXXXXXXXXXXXX-XXXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXX--XXXXX

PF00005 // ENSGT00760000118965_2_Domain_1 (794, 959)

XXLFPP-TSGRAYIGGYEISRDMAQIRKSLGLCPQHDVLFDNLTVAE
HLSFYAQLKGLSQHK-CPEEVKRLLHTLGLEEKRDTRSRYLSGGMKRRLSIGIALIAGSK
---V-LMLDEPTAGMDAVSRRAIWDLLQQQKRARTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHIILVKEPDCDVEKVSA---MIQSHVPNATLE---NCAGSE
LSFMLPKGDMHXXX---X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXX
XXXXX--XXXXXXXXX-XXXXXXXXXXXXXXXXXX-----------------XXXXX---
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-XXX
XXXXXXXXX---X--XXXXXXXXXXXXXXXXX--XXXXXX-XXX-------XXXXXXXXX
XXXXXXXXXXXXXXXX-----XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX---X
XXXXXXXXXX-----------------------------XXXXXXXXXXXXXXXXXXXXX
XXXXX-----XXXXXXXXX-XXXXXXXXXXXGLHVAINIHFGMALLM---------SG--
FCLLSVSERSSKAKHIQFMSGVPVLVYWFSSFLWDAIIFIL------ILLLL--------
GVFKYCRVDIYISDYRFLD-TMLIFILYGWSSIPLMYLMGFLYQRPGTAY------AXXX
XXXXXXX--------XXXX--------------XXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-------XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXX--XXXXX---------------XXXXXXXX-XXXXXXXXXXXXXXXXXX------
-XXX----XXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXX--XXXXXXXXXXXXX
XXXXXXX--XXXXALKNISFSVQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGYTGAGKTSLFQILTEEETVTSGEVFID
XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX------------XXXXXXXXXXXXXXX
XXXX-XXXXXXXXXX---XXGNKRK-LSGIALL---------REPAVSFLDKPSPGMDPV
ARRLLWDTVARAREAGKAIVI--TSHSME----ECEALCT-----RLAIMAQGQLRCLGS
PQHLKSRFGSGYGLRAKVRS-------HGRH---EALQEFKAFVRLT----F--------
-P-GAVL-----EDEHQGMLHYHLPSEDLSWAT--VFGILDNAKEQYGLDDYSVCLIWLE
QVCLSFVYLQLPLEAEGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MVV
LRQFGLLLWKNYIL---QKRQILVTVIEICLPLLFAAILIALRHRVHSISHP--------
----------------------NATIYPA--ESVDELPGFFYRRH---PS--NPWELAYV
PSN--SSAVRSIAEAVERAL-------PISIRAQGFASER-------EFEEYVRVDNR-S
GSVLAAVVFKHRFNHSTAPLPLQVDYELRFKYSPRNAPRSEQTGLNPNLDRDWHTSYLFP
LF-QLPGPREAKFA--DGGTPGYIREGFLAVQHAVDRAIMQYHANASAASLLENIT-VVV
QRFPYPPYVNDLFVLAIQNQLPLLLMLSFTYTSLNIVRAVVHEKEKKL------------
---------------------------KEYMHMMGLSNWLHWSAWFLMFFLFLLVSVFFV
TVLFCVKVS-EQ----GAVLTNSDPTLV----------------------------FTFL
AIFSISSISFNFMVSTFFSRA---NVAAAAGGFLYFFSYIPYFFISPRYDLMSHSQKLAS
CLISNVAMAMGAQLIGMFEGK-GTGIQWRDLMKPISVDDNFTLAQVLGMLLLDSVLYG--
LVAWYVEAVFPGEYGVPQPWY-FFL------TPSY-WCGRPRTVIGKEKEEEEDPEKALK
SQYIEEEPSDLVSGI-KIKH-LSKVF-RVGNKVKEAVKDLTVNMYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLYSP-TSGQAYINGYEISQDMVLIRRSLGLCPQHDVLFDNMTVEE
HLHFYAG---FPASK-CPEEINHVLRILNLEDKRHSLTKALSGGMKRKLSIGIALIGDSK
---V-VMLDEPTSGMDPASRRATWDLLQQQRSNRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKRK-YGAGYHMVMVKEPYCNLGEISR---LICQYVPNATME---SNAGAE
LSFILPKESTHRFE---A-LFTELEQKREELGIASYGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRSNDWAMDDSS-------------SLSGMT-DMTDDSGAL-
----ITEDCSSIKLNTGFYLCCQ-QFYAMFMKRAMYSWRNWKMVA-AQFLVPLIFTAFAL
IVAKTFPGP-----RDSSLLRLTLEPYGQTIV---PFSVPATSA-------LSQKLAEQY
VELLDAQRQAPLE-VL-----GGLEEYLISRASEEGGAFNEHYIAAASFEGAGNRTMVTA
LFNNQAYHSP-----------------------------ATALMLADNAVFRVLAGPNAS
ITVTNYPQPRNITEKAKDQ-LME-----GQTGFAIAINLLYGMASLA---------ST--
FALLLVSERAIKAKHVQFVSGVYVVNFWLSALLWDIINFLIP-----CALML--------
VIFQAFDVQAFTQDSHLVD-VMLIFLLYGWAIIPLMYLLSFFFSVAATAY------TRLT
IFNILSG--------TATFLA---VTIMSIPELGLVDLS-RTLDKVFLALPNYCLGQCIS
DFYQ-------------NYEFIQ-FCTSSVEAIF-------ICKAFNISYQMNYFSWESP
GIGRY--LTSLT---------------IQGFSFLFLLFLIETNLLWRLRTLVCGI-----
-CRRR---K--WVALLNRVSVLPEDRDV-----ADERKKVLESPPELLSSLSSPLVIKEL
TKVYDSR--ESLLAVDRISLAVSK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGDESITSGDAFVD
GHSILANIKKVQQ-RIGYCPQFDALLEHMTGRETLSMYARL-RGIPERYIGSCVENMLRG
LLLE-PHADKLVRTY---SGGNKRKLSAGIALI---------GGPPVIFLDEPSTGMDPV
ARR--WDAVTRTRECGKSIIF--TSHSME----ECEALCT-----RLAIMVNGQFKCLGS
PQHLKSKFGSGYTLLAKTRSD--------EE---GELQAFKAFVEKT----F--------
-P-GSVL-----KHEHQGMVHYHLTNKNLSWAQ--VFGALEKAKEKYRLEDYSVSQISLE
QVFMSFTR----------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAM
FRNLKLLLWKNFIL---KKRKTLVTVLEILMPLLFSTIIMYLRFASL-PRKY--------
----------------------PATNYRA--VDVTSLPEFFHHFP---VE--NKFQLIYI
PSQ--SETLKTIIEMVEQAF-------DVEFEVLGYSSVP-------SFERFIIEDPK-A
FYALAGIVFDHSFSDSKEPLPLEVKYYLRFSSIQRNFQV-S-MAIFQDDVKGWSTSFLYP
PN-PSPEPRNFDYS--DGGSPGYNKEGFLAIQHAVDKAIMQYHAHNVMTKMFENLS-VLV
KRFPHGAYVQDNFFLVLQNEFPLFLLLSFICSELIIINSIVLEKERKLK-----------
----------------------------EYMCAMGLVNWQHWVAWFIIFFISSFIVVSFM
TILFCTKVK-N-----VAVFRNSDPSLI----------------------------FIFL
MCFAIATILFAFMVSTFFQKA---HVATAAGGIIFFFTYLPYLYLAFTYTQRSHFEKIAF
CLFSNVAMALGVRLISRFEIR-GTGIQWWNMG---SVNGEFNFTQVLLMLLLDSFLYS--
LVAWYVESVFPGEYGTPKPWY-FFV------MPSY-WRGESKPLTRSV-LDVGNPEKAPK
NKFIQEEPTNLMKGI-EIQH-LHKVF-HKGRNEHIAVKDLTMNLYQ---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TCSILTGLIPP-SSGQVYINGYEISQDMVQIWKSMGLCPQHDILFDNLTVSE
HLYFYAQLKGLSRQK-CPEEVKRMLHMLGLEDKRDSRCRFLSRGMKRKLSIGIALIAGSK
---V-LMLDEPTSGVDVVSRRAIWNLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYYVTLVKKPHCNTEQISH---LIYHHIPNAVFQ---SSIGEE
LTFILPKESVHRFE---S-LFTELELRQVELGIASFGASVTTMEEVFIR--VNKLVDSST
DIQAI--RLSSVHSQQ-LINRLSTWYYSSLFSKRV-------VP-INTPGVV--------
--FSPH-PHLLKIFANLFDLLCQ-QFYAMLLKRAKFSWRNWLLMLSLQILVPLAIIMLSL
TILNFQI-N---V--DDVPLELTLKTYGQTTV---PFFISPNSR-------LGPRLSQHF
TDMLIAEEQIPLE-IL-----SSVEAFLLKKAEEEPEGFDQNYIVAASFEDVGNNTIVTA
LFNNQAYHSP-----------------------------AVALALVDNVLFKLLSGARAS
IVVVNNPQPMSLVETTEDF-LYQ-----GLRGHYLVISLLFGIAFLS---------SS--
FSILTVKERAVKAKHVQFISGVYVAIFWFSALLWDLVSLLIS-----TLLLL--------
VVFLCYNEEAFTHQENALA-VILLLMLYGWAIIPFIYLTSFCFHNAGGAF------VKLI
IVLIFLS--------ICPF--IL-VTVTSEKDLGYKAVS-ESLDHTFLLFPGHCLGMAFS
NLYY-------------NFELRK-FCNMRNLSHTECNEY-----TIQWF--LNIYAWESL
GIGKY--VTALA---------------ILGPVYIILLFLIETNVLWELKAR-FSG-FY--
-KKGK---L---V-TLHSEVAVPGDQDV-----EEEAKMIETYLEKLC--EKNPLVLKEV
SKVY-AK-KVPPLAVNKISFTVQAEE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TSLFKMLTGEEPITSGDAFVK
GLNLSSHLGKVRQ-HVGYCPQFDSLLGYMTGREMLIMYARL-RGIPEHHISAYVEQILDD
LLMY-MYANKLVKTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWGAVARARKSGKAIVI--TSHSME----ECEALCT-----RLAIMAQGQFKCLGS
PQHLKSKFGSGYALRAKVQS-------DGQQ---KALDEFKAFVDLT----F--------
-P-GVVL-----EDEHQGMVHYHLPGDDLSWAK--VFGTLEQAKSKYMLDDYSVNQISLE
DIFLSFTCPVPPTQGENK------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLLT
FSQFAVLLWKNFTL---KRRQVFTLILEILTVLVFPVMILLFRKLTS-INVV--------
----------------------GPYNYTS--QPINTLPPFLKNP--------EDWELIYV
PSN-

PF12698 // ENSGT00760000118965_2_Domain_0 (185, 665)

-IDVVSEITESMKRNL-------NISVKVRGFASEI-------EFERYIEYDYG-S
HKVLAAIIFDCNFKSSSDPLPLQVEYHLRFVRIQRTLM--------WPDRTGWQTSLLFP
AY-PTLGPRNVNYD--DGGDPGYIREGFLAVQHALDKAIMLYHESNASRNMFDSTS-IFI
RRFPHPAYSHDELIFIISSFLPLMFILMFSPTVLSIMRYIVWEREKRLK-----------
----------------------------EYQLIIGLQNWIIWAAYFFTFFFFYIIIISLI
CVLFSA--KIFS----EPIFRFSDSSFI----------------------------FVFL
MCYAIASIFFAFMVSTFFNKV---HLAASAGSLLYFAAFFPFNTIIKHYGHMTLTQKVTV
CLSSNVALALGISRLLKLELK-QIGVRWDNIWRPVNLEDNLIFGYILLMLLLDAFLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YMETIFPGQCGVPQPWY-FFL------LRSY-WLGETKIREK----KEVKNCGQTP
NKHFEAEPTSLVAGI-QIKH-LH-----KEFGDKVV

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNMSLNLFK---GQITILLGQ-N
GAGKTT--ILSLLTGRYPP-TREEVYIHGFDISKNIMEIRKNLGFCPQQDLLFNDMTISE
HLFFYSVVKRIYQNM-YSMEIDHMLSTFNLLEKRDTLSKALSGGMKRKLSIIIALMGGSQ
---V-VLLDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1294)

SSGMDPVSRRATWELLQQYKQNRTILLTTHSMDEADLLGDRIAIMVRGT
LQCCGSSVFLKQT-YGAGYHIVMEKESHCDVEKISE---IIHSHIPDATVE---NFTGAE
LSFILPKEYTHRFE---A-LIDHLEKKQKELGIASFGASITTMEEVFVK--VNNLADSQM
DIQAT--HFPFLKDQK-MGQDMKWNMNMPRYH------------------ETSV------
--YSRLNEMANIKFNTGFPLYCQ-QFHSMFIKRALFTWRNWKLML-LQISVILVFTTYLL
LTVQF--------HYDLPTRELDLSQYGRTIV---PYSISGNSD-------LALNLINNI
KIFLKRKNQELWE-VP-----GKVTKYL-----

PF12698 // ENSGT00760000118965_2_Domain_2 (1294, 1717)

MENKEFRDFSITALSIEVEENKTILTV
LFNNEAYHSA-----------------------------ATSLAVLDNVLFMSLSGPNAS
IKVANKPQPL--PLHGSHI---M-----PKNGLQIVICLAFSLAVLI---------GT--
FCLQTVTERTTRGKHIQFVSGVSVLTYWLSALLWDLIYFSIF-----CCLLL--------
GVFTYCRMDAFVANYNFLD-TMMILMLYGWSAVPLMYLGSFLFSSSTAAY------IKLT
LFNYFST--------IFSISIYIIRQHYD---LDFPHYIRTLIDSVLVMLPSYNFAMSIS
KFFN-------------DYEMKK-LCTRQF--PKIYVN----CSKT--FIKNSVYNFGKH
GIAKF--LIALA---------------ILGLFYLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LLCLETTS-WSLENFVFHKIISN-
VHNIFTKGKKSTVSCQ--VINDYEDEDI-----KNEENRALSLPP---KLKNTPLVLKEL
TKIYYKC--PVVKAI

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLVVQKSE-CFGLLGLNGAGKTTTFKILTGEETTTSGAVLID
GFNITKNIRKIRS-RIGYCPQDDPVLNHMTGQEVLIMYARL-RGVPEPDISKYVETFLYA
VQLE-ANADDFVHIY---SEGNRRRLNTAIALM---------GESSVVFLDEPSTGLDPV
ARRLLWNTITWMCRS-KAIII--TSHSME----ECEALCT-----RLAIMVKGKFKCLGS
PQHLKNKFGNAYSLTAKIKF-------ENNK---SKLEKFKEFIATT----F--------
-P-GNLHFCYIINQEHQGIICYYIPKQEICWGK--VFNILEEAKALFNLEDYSVSRITLE
QIFLTIANIDKTESIQEIKLL---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
FRQLGLLLWKNYIL---QKRQVLVTVIELALPLLFSAILIALRHRVPSVTYP--------
----------------------NATLYRE--MPFPNLPF----IP---GP--RPWELAYV
PSH--SKAAHSIILDVGNHLFPY---YFANQSARGFPTEE-------DFEDYIRHNNH-S
SKILAAVVFEHNFNHSGDPLPLQVRYRLRFKYSPRNAPMSEQTGLNPNVDRNWHTRYLYP
LF-QMPGPREAGDK--TGGTPGYQREGFLAMQHEVDRAIMRYHANESGRLLLDNID-VAI
RRFPYPPYVNDLFILAIQNQLPLLLMLSFTYTSLSIVRALVLEKERKLK-----------
----------------------------EYMRVMGLSSWLHSTAWFIHFFLLLLVSVFFV
TLLLCIQVS-SE----GAVLTRSDPSLV----------------------------FVYI
LVFSVSTISFSFMISSFFSRA---NMAAAAGGFLYFLSYIPYFFISPWYDELNHGAKVSS
CLFSNVGMAMGAQLIGMFEGK-GTGAQWSNLFTPVSVDDNFTLGQVLQMLMLDCVLYF--
LVGWYVESVMPGDYGVPQPWY-FCF------LPSY-WCGTPRLVEGLEKEDDEDPEKALK
GEYLEEEPSDLVPGI-RIKH-LTKVY-HASGKKRIAVRDLTLNMYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQVTVLLGH-N
GAGKST--TLSMLTGLSPP-SSGECYIGGYEITRDTALIRRSLGLCPQHDVLFQGLTVEE
HLYFYAGLKGCPRWC-CPEEVEKILQILRLEEKRNALSTQLSGGTCRKLSIGIALIGGSK
---V-VMLDEPTSGMDPASRRDTWELLRQHKHDRTLLLTTHFMDEADILGDRIAILAQGQ
LQCCGSPLFLKCK-YGAGYHMVMVKEPHCQVEDITH---LITSYVPNATLE---SNAGAE
LSYILPKESTHRFE---P-LFSELELRREELGIASYGASVTTMEEVFLR--VGKLVDTSL
DIQAI--QLPPLQYQH-ERRANDWGTEESC----------------SMS-DCTEDSG---
--TLITEDCSNIKLNGKCTLWCQ-QFYALFVKRAAYSWRNWKMVV-GQFLVPLVFTTLAL
VVGKTFPGP---Q--DSPPLDLSLVPYGYTVV---PYSLPPNAST------LLQSLADNF
RDQFSGQQMEPQE-VL-----DDLDNYLLTRASDEGALFAERCLCAADIQNLGSRIKVTA
RFNNQAYHAV-----------------------------ASALALVDNALFKLIAGPEAS
ISVTNYPQPRNTTETAQDQ-LLE-----GQAGFAIAINLLYGMASLA---------ST--
FSLLLVGERAVKSKHVQFVSGASALSYWLSALTWDLLNFLIP-----CTFML--------
AVFQAFDVRAYTEEHHLVD-VILMLLLYGWAVIPLMYLFSFLFTSTATAY------TRLT
IFNILSG--------TASF--LS-VTIMSIPALGLVDLS-HILDQVFLVLPNYCLGRSFS
DFYQ-------------NYHLLK-FCRSSPRSAIICQAF-----NI--TCQDNYFSWSSP
GVGRY--LTAMA---------------VQGSAFLCLLFIIESQIFCRLYNL-CR------
SYKEH---RWASLPESP--VSPPEDRDV-----ADERKKVLESPLEQLSALSSPLVIREL
SKVYGRR--ALVLAVDRISLAVGR

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFRMLTGDETVSSGDAYID
GYSILRHIKKVQQ-RIGYCPQFDPLLDHMTGRETLCMYARL-RGVPEGYINSCVENMLRG
LLLE-AHANKLVRTY---SGGNKRKLSAGIALI---------GGPSVIFMDEPSTGMDPV
ARRLLWDAVTRTRENGKAVII--TSHSME----ECEALCT-----RLAIMVNGQLKCLGS
PQHLKNKFGSGYTLLAKTSR-------G--A---EELMAFKDFVETI----F--------
-P-GSVL-----KHEHQGMVHYHITSQELSWAQ--VFGTLEKAKEKFDLEDYCVSQISLE
QVFLSFSHFQQSPAGGV-------------------------------------------
------------------------------------------------------------
---------------------------------------------

--------------------------------------------------------MAVE
FRQFTLLLWKNFVL---KKRQWILLIMEFILELLFTVILLMVRNSGS-VKHM--------
----------------------NALMFAN--QSVQSLPSYFLDAS---VR--RDWELAYI
PSN--SDIVKELIKMVQQTL-------LNTFTIRGFTSEE-------AFEEYIKHNRN-S
DRVMAAVVFNHDFVR-SKDLPLQVSYKLRFRYSLRNTVPTTRLLMIPKEDYGWNTGHLFP
VY-PSSGPRNPLED--DGGAPGYIREGFLAVQNAVDKAIIHYHANDSAQRLFDSID-VYT
KRFPFPAFLIDNYLTFLGQIWPPMILLLFSLTVFTILRTIVWEKETKLK-----------
----------------------------EYLLIMGLRSWQLWSATFITFFLTLLVTISLM
TMSLFIKLR-SDVIVKLPVIRYSDPTLV----------------------------FSFL
LLYGITTILFAFMLTTFFSKA---NTAITIGGFIYFVSYLLYFIISPHYVWMPFRGKLFS
CLLSNVAMTFGINLLIKLESI-EVGVQWRNLKKPFGLTDNFAFGHVMVMLLVDAFLYA--
VVIWYMEAVFPGEYGVPHPWY-FFG------KSSY-WDKDTKPILTRR--KKHLGVKKQD
DEFFEPEPENLVASI-QIKN-LSKIF-EVGNTFKEAVRDLTLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITALLGH-N
GAGKTT--VLSLLSGLFPP-TRGKAYICGFDISKDMFHIRKNLGLCPQNDLLFDYLTVSE
HLYFFARLKGLPREM-CQSEINNILNVFKLQDKRHSFSNSLSGGMKRKLSVSIALVGNSK
---V-VMLDDPTSGMDLISRRATWDLLQQQKRGRTILLTTHSMDEADLLGDRIAIVAKGN
LQCCGSSLFLKQK-YGAGYHMVMTKEPQCKATEVAS---LIYNYVPNAILE---SNIGAE
LSFILPKESANRFE---D-LFTELEDHQVSLGIASYGASVTTMEEVFHR--VNKLTDSAT
DLQAT--HLTSEHDHK-GIQSCLATLDDKP------------------------KGD---
--FLMPEDLPNIRFNTGVILCIQ-QFYALLTKRALYTFRHWKIMS-LQILILLLFTTFLL
KAVSYYSEV---K--NAPVLGMDLHQYGQSIV---SYAVSVQTE-------LTVQFTDHI
KLILTNEKQRPHP-VT-----GNIEEFLLKSRS-----CRERCIVAISLDVQKSKTIVTA
LFNNQAYHAA-----------------------------PVALSLVNNVLFKLLSGPGAS
ISVSNKPQPPTARQAIKQQ-FHE-----GSKGHDIAFSLFFGTAIVA---------SS--
FSLLTVSERVCKAKHIQFVSGARVGIFWLSALFWDIIVFFIS-----SSLLL--------
VVFYICNVKAFFEDNHYAD-ALLILMLFGWSTIPFIYLMSFLFSSSAAAY------TGLL
AFNFLTG--------ISSF--LL-VYMIDTNMIDLGRFN-QILVSTSFLFPTHNLGKSIS
GFYD-------------NFRTQR-YCAASSS--EDCNMN-----NI--TYEENYYGFEGH
GIGKY--VTAMI---------------VTGFLFLILLFIIEINL-LTFRSL-YSNLLYCH
FLKKR---KMVQVSDRS--SLVPDDYDV-----MDEQDKVLECPPGNLSSLNSPLILKEL
LKIYFQW--VPVVAVNRLTLAVHK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFSGAGKSSIFKMLTGDETITSGEVIFD
DKNISKNIQKIRQ-RISYCPQYDPLLEHLTGYEMLALHARL-WGVSEHYIPDYVKNMLSA
LFLG-AFGDKLIKNF---SSGAKRKLSTGIALL---------GKPDVIFLDKPSSSMDPV
ARRLLWDTVSRIRESSKAIVI--ISHSME----ECEALCT-----RLAVMENGKFKCLGS
PQYLKNKFGSGYTLLAKIKR-------NKSL---VELQALKTFIKTI----F--------
-P-DSSL-----QHEYQRMIHYHIPRKDLTWGQ--VFGILESIKDEYGLEDYSISHNTLE
QVFLSFAQTQIQKQQNFK------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVHRAL-------GINMRVHGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYLWTQTGFFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATRQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIASSFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWQDLLSPVNVDDDFCFGQVLGMLLLDSMLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFI------MPSY-WCGKPRTVTGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDSLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHTLGLEDKWNSPSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKRDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPTDGIGAL-
----IEEERTTVTLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPVTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSIPGTSR-------LGQQLSEHL
KDSLQAEEQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTV-TA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIAYQENFYAWSAP
GVGRF--VASMA---------------TSGCAYLLLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIEINLLQRLRGILCVF-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSSDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHSISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGQNLSWAK--VFGILEKAKEKYSVDDYSVSQISLE
QVFLSFAHLQPSATEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNQLI
VKQLTVLLWKNFTL---KKRQMISSV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

TEIMAALLFVMMLLIFRAFTN-ITIA--------
----------------------GPYHFKP--QPIVTMPAFIKDA--------KEWELVYI
PSD--IDVVTEIIENIKKNL-------NTTIKVRGFPSEA-------EFEEYILFDYT-S
EKVLAAIVFDCGFKNKNDPLPLQVKYHLRFIGTQRTIW--------WPEKLGWKISFLFP
NH-PPIQPRNPNFI--DGGSPGYITEGFLAVQYALDASIMLYHENSAGKKLFDEIN-VLI
QRFPYPAHPYDKLLWISSPFFPLMFILTFSSIVLSIIRSIVFEKEKRLK-----------
----------------------------EYQLIIGLKNWIIWAGYFFTFFPLYVIIILLI
CALLFI----AK----EPVLRYSDSSFI----------------------------FVFL
TCYAIASICFAFMVSTLFDKT---HVAASAGNLLFFASFFPYNFISENYGMLDLSTKVTA
CLSANVALALGINLLIKLEIK-EIGVKWRNLWTPASLEDNLLFSYMFGMLLLDALLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YVETVFPGQYGVPQPWY-FFL------MRSY-WFGKPKIRKT-A--E-ETKCLPTK
HNCFEAEPTNLVAGI-QIKC-LH-----KEFKNKPA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNLSLNVYE---GQVTVLLGH-N
GAGKST--TLSVLTGLYWSPFRAKAYINGYNISDNMIEIRKDLSFCPQHDLLFDDLTLSE
HLFFYWTVRGKAKDV-YCRDIEHMLSVFNLKDNYHSLSGSVSEGVRRKLSIIIALLGSSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1293)

SSGMDPMSRRATWDFLQHHKRHRTILLTTHYMDEADILGDRIAIMVRGT
LHCCGSSVFLKQI-YGAGYRIVMEKEPYCDVYNVFA---MIQHYVPDAVLD---NDLGSE
LSFILPKKYVSRFE---A-LFTELEKKQEALGIADFGASITTMEEVFLK--VNKMAAPQR
NIQDI--KPYYLTYEK-MRQDKQQNVNIPRNY------------------NSQS------
--FPYLREINTIKFNTGFLLYRQ-QFCSMFIKRALFMWRNWKLML-LQIIVIMVVTTYLL
LSLHLD-------DNDLPERELDLSHYGRTIV---PYSISGDSD-------LALNLKKNL
KIFLQSKNQNLRK-IR-----GDINDYI----

PF12698 // ENSGT00760000118965_2_Domain_2 (1293, 1582)

-LGSKECRNFCIIALSIKVEKNKTVLTV
FFNNEAYHSS-----------------------------AISLAALDNILFMTLSGPNAS
ITVFNKPQP--HPYNGPNR---V-----PVSGLQIVQCLAFGISVVV---------GT--
FSLQTVTERISQAKDIQFLSGVCVLTYWLSALLCDLIFFSIP-----SCLLL--------
GVFRVCQVDAFVVSYNFVD-IMLIFMLYGWCVVPLTYLGSFLFQSSTTSY------IKLT
LFNYFST--------IFSIVI

ENSGT00760000118965_2_Linker_2_3 (1582, 1816)

STLLKFYD-------------------------------
-------------------------------------------------TQNNVYGFGEH
GIGKF--LVMLA---------------AMGLVFLLLLLCLEAVS-WNLKNLVFRNILFY-
FYNKFRNSRQAVESDL--GSKEEEDEGI-----QEERRKAHTLL---LTSQHTPLVLSEV
TKIYFKC--PVVEAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLVVRKSE-CFGLLGLNGAGKTTTFKMLTGIETITSGVALID
GQSVTKNPRKIRS-RIGYCPQSESVLNHMTGRELLIMYSRL-WGVPEQDIKEYVETFLHS
VHLE-PIADQLICTY---SGGSKRRLSTAIALM---------GKSSVAFLDEPSTGMDPV
AQHLLWDTVTWICKTGKAVII--TSHRME----ECEALCT-----RLAIMVNGRFTCLGS
PQHVRKRFGHVYTLTVKINI-------AKNE---DKVEEFKKFIEAT----F--------
-P-GNIK-----NQEFQGIIGYYIPSKEICWGR--VFGIMEEAKELFNLEDYSFKQVTLE
QIFLTFANADRRRASEEINML---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MEV
LKKLKLLLWKNFIL---KRRKTLITLLEMLMPLLFCAIVLYLRLNSM-PRKK--------
----------------------SSTNYPA--VDVSLLPVYFYNYP---LK--SKFQLAYI
PSK--SETLKAVTEVVEQTF-------AVDFEVLGFPSVP-------LFEDYIIKDPK-S
FYILVGIIFHHDFNSSNEPLPLVVKYDLRFSYVQRNFVSPPRHLFFQEEIEGWCTAFLYP
PN-LSQAPREFSYA--DGGNPGYNKEGFLAIQHAVDKAIMRHHAPKAALNMFKDLH-VLV
QRFPFGPHIQDPFLVILQNEF

PF12698 // ENSGT00760000118965_2_Domain_0 (382, 664)

PLLLMLSFICVELIITNSVLSEKERKQK-----------
----------------------------EYMSMMGVESWLHWVAWFITFFISVSITVSVM
TVLFCTKIN-R-----VAVFRNSNPTLI----------------------------FIFL
MCFAIATIFFAFMMSTFFQRA---HVGTVIGGTVFFFTYLPYMYITFSYHQRTYTQKILS
CLFSNVAMATGVRFISLFEAE-GTGIQWRNIG---SVWGDFSFAQVLGMLLLDSFLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVESLFPRKFGIPKSWY-IFA------KK-------PVPEIPPL-LNIGDPEKPSK
GNFMQDEPTNQMNTI-EIQH-LYKVF-YSGRSKRTAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLSMNLYK---GQVTVLLGH-N
GAGKTT--VCSVLTGLITP-SKGHAYIHGCEISKDMVQIRKSLGWCPQHDILFDNFTVTD
HLYFYGQLKGLSPQD-CHEQTQEMLHLLGLKDKWNSRSKFLSGGMKRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1185)

SGLDSPSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSPSFLKQK-YGAGYYMTIIKTPLCDTSKLSE---VIYHHIPNAVLE---SNIGEE
MIVTLPKKTIHRFE---A-LFNDLELRQTELGISTFATSVTTMEEVFIR--VCKLADPST
NVLTE--KRHSLHPLP-RH-------H--RVPVDR-------IK--CLHSGT--------
--FPVS-TEQPMRLNTGFCLLCQ-QFYAMLLKKITYSRRNWMLV

PF12698 // ENSGT00760000118965_2_Domain_2 (1185, 1717)

LSVQVLLPLAIIMLSL
TFFNFKLRK---L--DNVPLELTLQTYGQTIV---PFFIAENSH-------LDPQLSDDF
VKMLVAAGQVPLR-IQ-----GSVEDFLLKKAKEAPEGFDKLYVVAASFEDVNNHTTVKA
LFNNQAYHSP-----------------------------SLALTLVDNLLFKLLSGANAS
ITTTNYPQPQTAIEVSESI-LYQ-----GPKGHYLVVNFLFGIAFLS---------SS--
FSILTVGEKSVKSKSLQFVSGVSTAVFWLSALLWDLISFLVP-----TLLLV--------
LVFLWYKEEAFAHHESIPA-VVLIMMLYGWAVIPLVYTVSFSFNTPGSAC------VKLV
VMLTFLS--------ISPV--VL-VTVTSEKDLGYTELS-DSLDHIFLILPGHCLGMALS
NLYY-------------NFELKK-FCSAKNLSDIDCNDV-----LEGYVVQENIYAWESL
GIGKY--LTALA---------------VLGPVYITM

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFLTEANAFYVLKSR-LSG-FFPS
FWKEK---SG--M-IFDVAEPEDE--DV-----LEEAETIKRYLETLV--KKNPLVVKEV
SKVY-KD-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFVVKEEE-CFGLLGLNGAGKTSIFNMLTSEQPITSGDAFVK
GFNIKSDIAKVRQ-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPECHIKACVDLILEN
LLMC-VCADKLVKTY---SGGNKRMLSTGIALV---------GEPAVILLDEPSTGMDPV
ARRLLWDTVERVRESGKTIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGISYSLQAKVRR-------KWQQ---QMLEEFKAFVDLT----F--------
-P-GSNL-----EDEHQNMLQYYLPGPNLSWAK--VFSIMEQAKKDYMLEDYSISQLSLE
DIFLNFTRPESSTKEQIQQEQAVLASPSPPS---NSRPISSPP-SRLSSPTPKPLPSPPP
SEPILL------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLGLLLWKNYTV---QKRKVLVTALELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQELPLFFSFPP---PG--DAWELAYV
PSQ--SDAVKTITEMVRKAL-------VINMRARGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHTFNHSAEPLPLAVKYHLRFSYTRRNYMWTETGSFFLKETEGWHTTSLFP
LF-PNPGPREPAAP--DGGEPGYIREGFLAVQHAVDRAIMQYHANASARQLLEKLT-VTA
KRFPYPPFISDPFLAAVQYQLPLLLVLSFTYTSLTAIRAVVREKETKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLVAVSFV
TLLFCVQVK-KG----VAVLTHSDPSLV----------------------------LVFL
LCFATSSISFSFMVSTFFSKA---NMAAAIGGFLYFFTYIPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GVGVQWRDLLSPVNVDDNFSFGQVLGMLLLDSVLYG--
LVTWYVEAVLPGEFGVPQPWY-FFI------MPSY-WCGHPQTVLGKEE-EDDDPEKVLR
TEYFEAEPEDLVAGI-KIKH-VTKVF-RVGNKGKVAVRDLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGRAYINGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLRFYAQLKGLSRRK-CPEEVQRMLHVLGLEDKQDTLSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPTSGMDALSRRAIWDLLQQHKSDRTVLLTTHFMDEADLLGDRVAIMAKGE
LQCCGSSMFLKRK-YGAGYHMTLVKEPHCDPEAISR---LVQHHVPTATLE---SRAGAE
LSFVLPKESTHRFE---G-LFSKLEKQRKELGVASFGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------HLCGAM-DPTNGVGSL-
----IEDECTTAKLNTGLALHCQ-QFWAMFLKKAAYSLREWKMVV-AQVLVPLTCVTLAL
LAVNYSSET-----FDDPKLELTLGAYGRTVV---PFAVPGASR-------LDQQLAERL
KGMLQASGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKQLCGPLAS
IMVSNYPQPRNTLQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVRVATFWLSALLWDLMSFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHMAD-ALLLLMLYGWAIIPLMYLMNFCFSGPAAAY------TRLT
IFNILSG--------VATFLM---VTIMRIPVVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFHE-------------NFETRR-YCTSSEVAAH-------YCKKYNIQYQQNFYAWSAP
GVGRF--VTSMA---------------ASGFAYLSLLFLIETDTLWRLKTCLCAF-----
-RRRR---A--LMEA--RTSAPPEDQDM-----VEERNRVLAPSMDSL--LDTPLVIKEL
SKVYEQR--APLLAVDKISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSEIGKRRH-PGAQREE------ELRGQA--VPRARLQRGAADS------------
---------RLNSQW-P-SGGG----------------------------------PGPV
AGVHGWRASLQRLP-----------CVFQ----SAEAVSQ-----WLSTF--------QL
QLYAPNFVGAGYDLPTISRMTPEVRRPEAGN---RAVTELRPWPPAHGPLLYLGPHGHWG
HQ-ARSS-----EEDHRGDQRPEHP-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

----------------------------------------------------MPPLHVRM
CKNLKLLLWKNFTL---KKRKPLVAVLEALTPLLFSAIAMYLRVHSV-PRKW--------
----------------------PPLNHPA--VNISLLPAFF-YFP---TQ--AKYQLAYI
PSQ--SDALRAVTEMVQDAF-------DVEFEVLGYSSVP-------VFENYIIQDPK-G
FYVWAGIVLDHSFRDSKQPLPLKIKYRLRLSSVHRSPLALK-VAADHEHLEGWCTGLRYP
LN-PSQVPRAFGHF--DGGLPGYSKEGFLTLQHALDKAIMRHHAHNATAQMFQDLT-VLV
KQFPHGAHIQDTFLLVLQSEFPLLLTLSFLCLELIIINSVAREKEKRLK-----------
----------------------------EYMCMMGASSRQHWAAWFLTFFISALIAVSLM
TVLFCTQVN-G-----VTVFRNSDPSLI----------------------------FVFL
LCFATATIFFAFMISTFFQKA---HIAAAAGGISFFFTYLPYLYFMFSYPQRTHFQKLVF
CLLSNVAMAQGVQLISTFEIK-GMGMQWKTIG---SVSGEFNFCQVLLLLLLDAVLYS--
VVAWYVEAILLGEYGVPKPWY-FFV------MPSH-WRRQSLLLTRSV-LDIGDLSKPAE
SKFFQEEPISLVKGI-EIQH-LYKVY-DTGRGSHRAVKDLTLNLYQ---GQITVLLGH-S
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--LCCMLAGLIPP-SGGWAYIKGYEISRDMAKIRRSLGWCPQHDILFPDLTVAE
HLSFYAQLKGLSHRK-CPEEVQRMLHMLGLEDKQDTLSRFLSRGMRRKLSIGIALIAGSK
---V-LMLDEPTSGMDALSRRAIWDLLQQHKSDRTVLLTTHFMDEADLLGDRVAIMAKGE
LQCCGSSMFLKWK-YGGGYYMTLLKKPHCNTEEICC---LIYHHIPNAVLQ---SSKGEE
LTFILPKKDTHRFA---S-LFTQLEARQEELGVANFQVAVTTMEEVFMR--VNKLSDSNT
DVQAL--KISSTQFQQ-------------RVSVSR-------IK--RIQSRI--------
--FSMQ-PGLPVQLNTGARLICQ-QFYAMFLKRFTYSWRNWMLMVTMQVLAPLAITVFSL
AFLSLDT-H---M--DEVPLELTLKTYGRTIV---PFYISPNSR-------LGPRLSEYF
TNMLEAEEQLPLE-TL-----GSVEDLLLQKEEEDPEVFDYKYVVAASFEDSGNHTTVTA
LFNNQAYHSP-----------------------------AVALALVDNVLFKLLSGARAS
ITAVNHPQPRTALEASEDI-LYQ-----GPKAHFLITNLLFGIAFLS---------SS--
FSILTVKERSTKAKDIQFTSGVYVATFWLSALLWDLITSFVP-----SLLQL--------
VVFLYYKEEAFTHEGNIPA-VLLALVLYSWASTPFVYLASFCLHYEGSAF------IKLF
ITLTFLS--------ICPN--IL-VWVTSQKELGYVTLS-DSLDRKFLLLPGHCLGMALF
NLYY-------------NYGIQK-LCKARKLDQQECNQL-----SEGSTVQESIYAWEPL
GMGKY--LAAMA---------------IMGFVYLVLLFLIETNVLWGLKAR-FPD-FNR-
----K---GL-LV-TMHEAASMPVDQDV-----EQEAKMVETYLEKLR--AENPLVLREV
TKVY-VQ-NVPLLAVNKISFTVGAGE-CFGLLGSNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TSIFKMLTGEEPITSGAAFVR
GLSISSHLREVRS-QIGYCPQFDALLNHMTGRETLVLYARI-RGVPERHIATCVEQILDD
LLMH-THADKLVKTY---SGSNKRKLSTAIALL---------GEPSVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRG-------DGQQ---EALEEFKAFVTLT----F--------
-P-GSVL-----EDERQGMVHYHLPGDDLSWAK--VFDILEQAKTKFRLDDYCVNQVSLE
DIFLSFTCSAHPTKEEHKQEQGEPADHSPTSPPPS--PRPSQPPSLFSSQPPSEPPSQSL
SPSPSQPPSPTSFPSTSQPPSPTSSPSPSQ-PPSPTSSPSPSQPPSP---TSSPSPSQPP
SPTSSXXXXXXXPSQPPSPTSSPSPSQPPSPTSSPSPSQPPSPLP

-------------------------------------------------------MDLLT
FNQFAVLLWKNFTL---KRRQFFTLTLEILTALVFPVMILVFRTHIA-IKVV--------
----------------------GPYSYTP--QPVNSLPSFLKNP--------EEWELTYV
PSN--IDVIQEIIENVKRNL-------NTSIKVRGFASEM-------ELENYLKYDYG-S
HKVLAAVIFDTDFKSSSDPLPLQVKYHLRFVRIQRSLM--------WPERLGWKTSLLFP
VH-PSVGPRNADYD--DGGSPGYIREGFLAVQHALDKAIMLYHESSASQKLFDNIS-IFI
QRFPHPAYSHDGLIWITSSFLPLMFILMFSPTVLSIMRSIVWEREKRLK-----------
----------------------------EYQLIIGLKNWIIWAAYFFTFFIFYIIIISMI
CILFSA--KIFS----EPIFRFSDGSFI----------------------------FVFL
MCYAIASIFFAFMVSTFFNKV---HLAASAGSLLYFASFFPFNTINQFYGQMTLTKKVAA
CLSSNVALALGISRLLKLEVR-QTGIRWNNIWTPVGLEDNLMFGYILLMLLLDAFLYG--
LVTWYIETVFPGQYGVPQPWY-FFL------MHSY-WFGEPKTRRK-K--EEMKNCGEAP
NKYFEPEPTTLVAGI-QIKH-LH-----KEFGDKVVVNNMSLNLYK---GQITILLGQ-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 912)

TT--VLSLLIGCYPP-TRGNVYIHGFDISENIIEIRKNLGFCPQHDMLFNDLTLSE
HLFFYSVVKRIYQNM-YCMEIDHMLSTFNLLEKRDTFSKSLSGGMKRKLAIIIALIGGSQ
---V-VILDEPLCGLDPVSRRATRDLLQQYKQDRTILVATNHMDEADLLGDRIAIMVQGT
LQCCGSSVFLKQI-YGAGYRIVMEKESHCDVEKISE---IIHSHIPEATVE---NFTGAE
LSVILPKEYTQRFE---A-LINDLEKNQKELGIANFGASITTMEEVFNK--VNNLAGSHM
DIQDT--HATSLKGQK-KGQDMKWNMNISRYH------------------ERAV------
--FSRLNEIAAIKFNTGFSLYCQ-QFYSMFIKRALFTWRNWKLML-LQILVILVFTAYLL
KTTYP--------QSDLPTRELDLSQYGQTIV---PYSVSGNSD-------LALNFINNL
KIFLKRNNQELWE-VQ-----GKVTKHI-----MENKEFRDFSIIALSIEVEKNKMILTI
LFNNEAYHSA-----------------------------ATSLAVLDNVLFMSLSGLNAS
IRTSNKPQPL--PLHGHII---I-----PTNGLQIVICLAFGMAIVV---------GN--
FGLQTVMERTTRAKHIQFVSGVSVLTYWLSAFLWDLICFCIL-----CFLLL--------
GVFTYCGLDAFVANYNFLD-TMMIFMLYGWSVVPLMYLGSFLFSSSTAAY------IKLT
LFNYFST--------IFSISVYVIRQQYA---T---------------------------
--------------------------------------------------EKSVYNFGTH
GIAKY--LTALA---------------VLGLFYLLLLLCVETTS-WSLQNFISHKILSN-
VHNLFTKGMKAVVSCQ--VVKEYEDEDV-----KNEENRALTLPP---KLKNIPLVLKEL
TKVYYKC--PVVKAIRNISLVVQKSE-SFGLLGLSGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKILTGEETTTSGAVLID
GFNITKNIRKIRS-RIGYCPQNDPILNHMTGQEMLMMYARL-QGVPEPDICKYVETFLYA
MHLE-TNADEFVHIY---SEGNRRRLNTAIALM---------GKSSIVFLDEPSTGLDPA
ARCLLWDTITWMCKRGKAIVV--TSHSIE----ECEALCT-----RLAIMVKGRFKCLGS
PQHLKNKFGNAYTLTAKIKF-------ENNE---DKLEKFKEFMTAT----F--------
-P-GNIK-----HQEHQGIISYYIPKEEICWGK--VFNILEEAKELFNLEDYSVSQITLE
QVFLTIANIDKTENIREIKVL---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------LLV
LNKFMVLLWKNFTL---KRRQCTALAAELILTVLFVGVLLLTRRFSY-REKT--------
----------------------GPFNYPP--QPVDELPVFLRE-V--PAS--GVWELAFV
PSK--SVVVKDIVETVKRDL-------HYNFKVQGFPSER-------DFEDYVKQGNN-S
ERVMVAFVFDHEFKNSHDPLPLKVKYYLRFSSSQRNE--Y----VGFFRPGSWETDTLFP
KS-PSIGPRSGPEA--NGGSPGYISEGFLLMQHALDKAIMKYHNHKTAQQLFTNVH-VFV
QRFPYPRYDNDFFYILFSDFAPLVILFVFIVNYLTIIQSVVWEKENRLK-----------
----------------------------EYQLMIGLSNWMLWAAYFFTFLTLYLVIIFLT
CLLFFVKMK-P-----LPIIQYSDPSLV----------------------------FVFL
LCFAIATIFFSFMVSTFFSKA---HFAIAIGGFIYLISYFPAPRISSSYAQMTLIEKLAF
SLSSNVVMALGTKYLVRAEIN-KIGIKWSNIFSPNTV-ENFVFAYILGTFLLDAVLYG--
LVAWYIEAVFPGEYGVPKPWN-FFL------LPSY-WFGEKPKK--TN--ESRQFYKTIE
TKYFEAEPTDLVAGI-QLQH-LCKEF-RVHNTTKLAVKDLSLNVYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKST--TLSILSGLYPA-TSGEAYVNGFAISKQMVQIRKSLGLCPQQDLLFNYLTVSE
HLYFYCMIKGVPRKM-YPIEIDRMLSAFNLIEKRNAFSASLSGGMKRKLSVIIALIGDSK
---V-VILDEPTAGMDPASRRATRDLLQQYKQGRTILLTTHYMEEADILGDRIAIMVKGS
LRCCGSSLFLKNI-YGVGYHIVIVKAPHCNVPNPKQLKILFHFHAPDSMLVTPPSGWGSP
LGFLVSLDSYSRFE---A-LFADLERRHTELGIDSFGVTITTMEEVFFR--VGNTEETQT
DIVST--QPQPLSQMS-EVSVKNQNRNMSRN-------------------EGAD------
--LSTVNERPAVMFNTGCSLYHQ-QFCAMFIKRAIFNWRNWKLIL-LQILALLGSLILLS
ETVMFT------HSNDDKARLMSLSQYGQTIV---PLSISGNSN-------LTLIFLKNL
KSMLEPDNHTLKE-VQ-----GDLLKYL-----MENEDCIHLCIVAFSIEVKKDKITFTG
LFNNQAYHSP-----------------------------ALSLAMLDNILFMSTSGPDAS
ITVFNKPQPTSTYKKY----SSM-----LPEGDQVAINIHFGMALLV---------SG--
FCLLTVTERITKAKLIQFLSGVYVLAYWLSALLWDLTIFFIA-----CCLLL--------
GVFKFCQLDEFLTDYHFLD-TMLIVMLFGWSAIPLIYLLSFLFSQSTSAY------IKLV
VFSYLSG--------ICSLIIDATFQFAS-YLK--LEALRTFILRLLLLLPNYNLGKCFM
NYFT-------------FYKNKK-MCME-N--PYASLD----CDEKTSQKRNFSYKWEKK
GIGLY--MVMMS---------------TIGFICLLLVFFCDTTL-WKSPRTWLCK-TLQ-
IYSVHQIF---YSLDF--LDSECEDEDV-----ENERKRILEQPQ---ELLNSSVLIKEL
IKIYFKC--PVILAVKNISITIQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGLNGAGKTTTFQILTGEETATSGHVFVE
GFSITDNIQKVKS-RVGYCPQSDALLEYMTGREIMIMYARL-WGVSESQIQLYVSKWLTS
LQLE-SHADRIIRTY---SGGNKRRLSTAIALM---------GKPTIILLDEPSTGMDPV
ARRLLWDAVMQARESGKTIII--TSHRME----ECDAFCT-----RLAIMVKGKFVCLGS
PQHLKNKFGDVYILKVKVKT-------DTHK---HTLNDFKDFITMT----F--------
-P-GSEL-----KQENQGILNYYIPRKDNSWSK--VFGVLEEAKEQFNLEDYSVSQITLE
QVFLTFANLENNGLDGNK------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------SG--
FCLLTVTERVTKAKHIQFLSGVYVPVYWLSALLWDFIIFFIT-----CCLLL--------
GAFKFCQLDIYIMDYHFLD-TMLIFTLYGWSAIPLMYLLSFLFTRSTSAY------IKLV
LFNYLSG--------IFSLLIDATLQFEV-Q-HKMSITTRAFILDSLLFFPNYNLAKCIS
DYFT-------------FYQIKK-WCSG-NK-PPTYIN----CSKENTAKN--IYSLEEK
MIGKY--VIMMS---------------ITGFICLLFIFFLDTNL-WKLRTFFNQYIYFG-
IYKTFRKG---KVSKE--LSGESDDEDV-----QNERQRILGQPQ---EFLDSTVLIKEL
TKIYFKY--PVILAVKNISVIIQR

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKILTGEETVTSGDVFIE
HVSITKSLQKVKS-RVGYCPQSDALLEYMTGREIMIMCARL-WGVSEPQIQLYVNKWLSS
MQLE-PHADKLIRTY---SGGTKRRLSTAIALM---------GKTSVVLLDEPSTGMDPV
ARRLLWDVVTWTRERGKAIII--TSHRME----ECDAFCT-----RLAIMVQGKFLCLGS
PQQLKNKFGNIYILKVKVKI-------DAQE---DKLDGIKYFITLT----F--------
-P-GSVL-----KQENQGILTYYIPSKDNSWGK--VFGILEDAKDQFNLEDYSISQITLE
QIFLAFGTPENTEGDYKERYH---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLTLLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QSIQELPLFFSFPP---PG--GTWELAYV
PSH--SDAARTITETVKREF-------MIKMRVHGFSSEK-------DFEDYIRYDNH-S
SSVLAAVVFEHSFNHSQDPLPLAVKYHLRFSYTRRNYMWTQTGNIFLKETEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIREGFLAMQHAVDKAIMRYHANTSAQQLFQKLM-VIT
KRFPFPPYISDPFLLAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLNSWLHWSAWFLMFFLFFLIVVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSALYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWH-FFL------MPSY-WCGNPRTVVGKEE-EGSDPEKALR
NEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKMGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSLLTGLFPP-TSGHAYIHGYEISQDMAQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKSDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGAL-
----IEEEEVLVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCLTLAL
LAIHYTSEI-----FDDPLLKLSLNEYGRTVV---PFSVPGTSR-------LAQQLSENL
RDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDRGELTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPRAS
IEISNYPQPRNTLQVAKDH-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLVP-----SLLLL--------
VVFQAFNVHAFTRDGHMAD-LLLLLMLYGWAIIPLMYLMSFFFSAASTAY------TRLT
IFNILSG--------IATFIV---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSELAAH-------YCKKYNIQYQESFYAWSTP
GVGKF--VTSMA---------------ASGGIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-RRRW---T--LAELQNRTSVLPEDQDV-----AEERSRILVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLINACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---DALEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LKKLKLLLWKNFIL---KRRKTLITLLEMLMPLLFCAIVLYLRLNSM-PRKK--------
----------------------SSTNYPA--VDVSLLPVYFYNYP---LK--SKFQLAYI
PSK--SETLKAVTEVVEQTF-------AVDFEVLGFPSVP-------LFEDYIIKDPK-S
FYILVGIIFHHDFNNSNEPLPLVVKYDLRFSYVQRNFVSPPRHLFFQEEIEGWCTAFLYP
PN-LSQAPREFSYA--DGGNPGYNKEGFLAIQHAVDKAIMRHHAPKAALNMFKDLH-VLV
QRFPFGPHIQDPFLVILQNEF

PF12698 // ENSGT00760000118965_2_Domain_0 (382, 664)

PLLLMLSFICVELIITNSVLSEKERKQK-----------
----------------------------EYMSMMGVESWLHWVAWFITFFISVSVTVSVM
TVLFCTKIN-R-----VAVFRNSNPTLI----------------------------FIFL
MCFAIATIFFAFMMSTFFQRA---HVGTVIGGTVFFFTYLPYMYITFSYHQRTYTQKILS
CLFSNVAMATGVRFISLFEAE-GTGIQWRNIG---SVWGDFSFAQVLGMLLLDSFLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVESLFPGKFGIPKSWY-IFA------KK-------PVPAIPPL-LNIGDPEKPSK
GNFMQDEPTNQMNTI-EIQH-LYKVF-YSGRSKRTAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLSMNLYK---GQVTVLLGH-N
GAGKTT--VCSVLTGLITP-SKGHAYIHGCEISKDMVQIRKSLGWCPQHDILFDNFTVTD
HLYFYGQLKGLSPQD-CHEQIQEMLHMLGLKDKWNSRSKFLSGGMKRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1185)

SGMDSPSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSPSFLKQK-YGAGYYMTIIKAPLCDTSKLSE---VIYHHIPNAVLE---SNIGEE
MIFTLPKKTIPRFE---A-LFNDLELRQTELGISTFATSVTTMEEVFIR--VCKLADPST
NVLTE--KRHPLHPLP-RH-------H--RVPVDR-------IK--CLHSRT--------
--FSVS-TEQPMRLNTGFRLLCQ-QFYAMLLKKITYSRRNWMLV

PF12698 // ENSGT00760000118965_2_Domain_2 (1185, 1717)

LSVQVLLPLAIIMLSL
TFFNFKLRK---L--DNVPLELTLQTYGQTIV---PFFIAENSH-------LDPQLSDDF
VKMLVAAGQVPLR-IQ-----GSVEDFLLKKAKEAPEGFDKLYVVAASFEDVNNHTTVKA
LFNNQAYHSP-----------------------------SLALTLVDNLLFKLLSGANAS
ITTTNYPQPQTAIEVSESI-LYQ-----GPKGHYLVVNFLFGIAFLS---------SS--
FSILTVGEKSVKSKSLQFVSGVSTAVFWLSALLWDLISFLVP-----TLLLV--------
LVFLWYKEEAFAHHESIPA-VVLIMMLYGWAVIPLVYTVSFSFNTPGSAC------VKLV
VMLTFLS--------ISPV--VL-VTVTSEKDLGYTELS-DSLDHIFLILPGHCLGMALS
NLYY-------------NFELKK-FCSAKNLSDIDCNDV-----LEGYVVQENIYAWESL
GIGKY--LTALA---------------VLGPVYITM

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFLTEANAFYVLKSR-LSG-FFPS
FWKEK---PG--M-IFDVAEPEDE--DV-----LEETETIKRYLETLI--KKNPLVVKEV
SKVY-KD-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFVVKEEE-CFGLLGLNGAGKTSIFNMLTSEQPITSGDAFVK
GFNIKSDIAKVRQ-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPECHIKACVDLILEN
LLMC-VCADKLVKTY---SGGNKRMLSTGIALV---------GEPAVILLDEPSTGMDPV
ARRLLWDTVERVRESGKTIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGIGYSLQAKVQR-------KWQQ---HMLEEFKAFVDLT----F--------
-P-GSNL-----EDEHQNMLQYYLPGPNLSWAK--VFSIMEQAKKDYMLEDYSISQLSLE
DIFLNFTRPESSTKEQIQQEQAVLASPSPPS---NSRPISSPP-PRLSSQTPKPLPSPPP
SEPVLL------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAP
FKKLKLLLWKNFVL---KKRKTLVTVLETLMPVLFSAIVLYLRLNSM-PRNK--------
----------------------ANTNYPA--VDVSLLPVYFHNYP---LK--SKFQLVYI
PSK--SETLKAVTEVVEQTF-------AVDFEVLGFPSVS-------LFENYIIKDPK-S
FYVLVGIVFHHDFNSSNEPLPLVVKYDLRFSYVQRNSISPPRHLFFQEDIEGWCTAFLYP
PN-LSQAPREFSYA--DGGHPGYNKEGFLAIQHAVDKAIMLHHAPKAALDMFKNLQ-VSV
QRFPSGSHIQDPFLVILQN

PF12698 // ENSGT00760000118965_2_Domain_0 (380, 664)

EFPLLLMLSFICVELIITNSILLEKERKQK-----------
----------------------------EYMYLMGLENWLHWVAWFITFFLSALVTVSGM
TVLFCTKMN-G-----VAVFRNSNTTLI----------------------------FIFL
MCFAIATIFFAFMMSTFFQRA---HVGTVIGGIVFFFTYLPYMYITFSYHQRTYSQKILS
CLFSNVAMAMGVRFISLFEAE-GTGIQWRNMG---SVWGDFSFTQVLVMLLLDSFLYC--
LVA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVESLFPRKIGMPKSWY-IFA------KCPL-WRKKSFPVIPPL-LVIGDPEKTSK
GDFLQDEPAGHINAI-EIQH-LYKVF-YTGRSKCIAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSMNLYK---GQITVLLGH-N
GAGKTT--VCSVLTGLIPP-SKGHAYIHGCEISKDMVRIRKNVGWCPQHDILFDNFTVTD
HLYFYGQLKGLSHQD-CHEKIEEMLHTLGLEDKRNSRSKFLSGGIKRKLAIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1185)

SGMDSSSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGTPSFLKQK-YGAGYYMTIIKTPLCDTEKLAK---VIYHHIPNAILE---SRIGEE
MIFTLPKKAMPRFE---A-LFADLEQRQTELGISTFGASVTTMEEVFIR--VCKLADPST
NVLTE--KRPSLRHLP-R-------NH--RVPVDR-------IK--CLHSRI--------
--FSLS-SDQPIRLNTGFSLLCQ-QFYAMLLKKVAFSRRNWMLV

PF12698 // ENSGT00760000118965_2_Domain_2 (1185, 1718)

LSVQILLPLVIIMLSL
SFFNFKLRK---L--DNVPLELTLQTYGQTIV---PFFIAENSR-------LDPQLSDNF
VKMLVAAGQVPLR-IQ-----GSVENFLLKKAKEAPEDFDKLYVVAASFEDVNDHTTVKA
LFNNQAYHSP-----------------------------SLALALVDNVLFKLLSGANAS
ITTTNYPQPQTAMELSETI-LYQ-----GPKGHYLVVNFLFGIAFLS---------SS--
FSILTVGEKSIKSKNLQFLSGVSMAAFWLSALLWDLISFLVP-----TLLLV--------
LVFFWYKEEAFAHPQSIPA-VVLIMMLYGWAIIPLVYTVSFSFKTPGSGC------VKLV
AMLTFLS--------ISPV--VL-VTVTSEKDLGYTELS-DTLDHIFLIFPGHCLGMAFS
NLYY-------------NFEIKK-FCNAKNLSDIDCNDV-----LEGYVVQKNIYAWESL
GIGKY--LTALA---------------ILGPVYITLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLTEANAFCALKAR-LSG-FFC-
--KQK---LR--M-LLNVTGAEDE--DV-----LEEAENIKYHLDTLI--KKSPLVVKEL
SKVY-KE-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFVVKEKE-CFGLLGLNGAGKTSIFNMLTREQPITSGDAFVK
GFNIRTDMAKVQQ-WIGYCPEFDALLNFMTGREMLVMHARI-RGIPECHIKTCVDMILEN
LLMC-VYADKLVKTY---SDGNKRVLSTAIALL---------GEPTVILLDEPSTGMDPV
ARRLVWDAVGRVRESGKTIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSRFGSGYSLQAKVRR-------KWQQ---QMLEEFKAFVDLT----F--------
-P-GSSL-----EDEHQSMVQYYLPGQNLSWAK--VFGIMEQAKKDYVLEDYSISQLSLE
DIFLSFTRPVPDTKENIQQGQAALDSSLSPS---NSRPISSPP-SSPPSSPPSSPPSRPP
SRPSQPPS-----R----PPSR-----------------HPSSPSQP---PSRPPSRHPS
SPSQPPSEPVLL---------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQQLPLFFTFHP---PG--GNWELAYI
PSH--SDAARTITETVQREL-------VISMKVHGFSSEK-------DFEDYIRYDNR-S
SNVLAAVVFEHTFNHSKDPLPLAVKYHLRFSYTQRNYMWTQTGNDFLREKEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIREGFLAVQHAVDKAIMHYHANASAHQLFQKLS-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLSIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFFLIMVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LVFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYYFTFIPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVVGKEE-EDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKVGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TMSMLTGLFPP-TSGHAYIHGYEISQDMAQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSLQK-CPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1048)

SGMDAVSRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKK

PF12698 // ENSGT00760000118965_2_Domain_2 (1048, 1718)

QKELGIASFGASVTTMEEVFL------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------R-----GRKGFDIALNLLIAMAFLA---------ST--
FSVLAVSERAVQAKHIQFVSGVRVATFWLSALLWDLISFLIP-----SLLLL--------
VVFRAFDVQAFTRDGHLAD-LLLLLLLYGWAIIPLMYLMSFFFSAASTAY------TRLT
IFNILSG--------IAPFII---VTVMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSWFAAR-------YCKKYNIQYQENFYAWSTP
GVGKF--VTSMA---------------ASGCIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-QRRW---T--LAELQNRTSVLPEDQDV-----ADERSRVLVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGKEMLVMYARL-RGIPERLISACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKH---EVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGQ------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDFSW
VYQFMALLWKNFIL---KRRRLMALFVEFTLTLLFAGTLLLTRKILT-IKKY--------
----------------------GPFNYSL--QPIDKLPAFLGMPM--IFP--GPWELAFV
PSK--SVVVKSIVDHVKRDL-------HYNFTVQGFSSER-------DFEEYVKQENN-S
EKVLVAIIFDHEFQNSDDPLPLKVKYYLRFSSFQRNK--Y----MGFVRTEGWETGVLFP
TF-PSLGPRSERSS--HGGSPGYITEGF

PF12698 // ENSGT00760000118965_2_Domain_0 (329, 664)

LAMQHAVDIAIMKYYNHKATQKLFREVT-VFV
QRFPYPAYSHDYFYTFFGIFIPLVILFIFSMNHLTLIQAIVWEKENRLK-----------
----------------------------EYLLMIGLSNWMLWAAYFFTFLSLYSVIILLM
CIIFFAKIE-P-----VPVIQYSDPSLV----------------------------FVFL
LCFAIATMFFSFMVSTFFNKV---HFAVSVGGFIYLVTYFPVVTVSINFVEMTFTQKLAS
CLSSNIAMGLGTKFLVKAEME-KIGIKWSNIFSPPKM-ENFGFAHVLGMFLFDAFLYG--
LVA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

WYIEAVFPGEYGVPKPWN-FFL------LRSY-WFGEASKG--KK--ERRQFYETNE
SKYFEAEPTNLVAGI-QIKH-LCKEF-RMQNTTKIAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYM---GQITVLLGH-N
GAGKST--ILSILSGLYPA-TSGKAYVNGYDTSKQIVQIRKSLGLCPQQNLLFDYLTVSE
HLYFYCLVKGIPRKT-RLVEIDHMLSTFNLLDKHNAFSFSLSGGMKRRLSVIIALIGGSQ
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1294)

SGMDPVSRRATWDVLQQYKEDHTILLTTHYMDEADILGDRIAIMVKGS
LRCCGSSVFLKKI-YGVGYHMVMVKEAHCNVEEILK---FIQYHIPEATLE---KNVNNE
ISFLLPKEYTHSFE---A-LFTDLEKRRYELGIASFGASVTTMEEVFFR--VNNMEDSQV
DIPAT--QTPPPSNQN-RNMSS----NE-----------------------RAQ------
--CSTMNESPAIMFNTGYSLYHQ-QFCAMFIKRALFSWRNWKLIL-LQMLALLGSFTFLS
KAENFL------HNNDEKARQMDLNQYGHTIV---PLSISGNSN-------LTLIFLKHL
RSMLESDKHTLKE-VQ-----GDLLKYL-----

PF12698 // ENSGT00760000118965_2_Domain_2 (1294, 1718)

MENEDCIHLCIVAFSIEVKTNKIILTG
LFNNQAYHSP-----------------------------SLTLSILDNILLMTIAGSNAS
LTVSNKPQPYLR----------------LSNGLHVALNIHFGMALLI---------SG--
FCLLTVTEQITKAKHIQFLSGVYVPVYWLSALLWDFIIFFIT-----CCLLL--------
VTFKFCQLDIYITDYHFLD-TMLIFMLYGWSVIPLMYLLSFLFTKSTSAY------IKLV
LFNYLSG--------IFSVLIDATLQFEV-Q-HKMSKATRAFILNSLLFFPNYNLAKCID
DYFT-------------FYQIKK-WCSG-NK-PPVYIN----CSKENTAKN--VYSLEEK
MIGKY--VIVMS---------------ITGFICLLLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFLDTTL-WKLRTFLSQYVYFG-
IYKTFRKV---ILVKL--SE-VVVHRDL----------------R---NLLYLIFKYSLL
YCIYFKY--PVILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISVTIQKGE-CFGLLGFNGAGKTTTFKILTGEETVTSGDVFLG
QFSITKRLQKVRHYYIGYCPQSEALLEYMTGREIMIMYARL-WGISEPQIQLYVNRWLNS
MQLE-LHADKLIITY---SGGTKHRLSTAIALM---------GNTSVILLDEPSTGMDPG
ARRLLWDAVTWTRESGKAIII--TSHRME----ECDAFCT-----RLAIMVEGKFMCLGS
PQHLKSKFGNIYVLKIKVKI-------DAQE---DKLNDLKFFITMT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNSWGK--VFGILEEAKEKFNLEDYSISQITLE
QVFLIFGRKRTYS-----------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------TLLLPSLPTCDP
SLGLHTHRFQNVVLLCRGRPRVLLSLK--PFPSLXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHGFPSEKNF-------EDYIKYDNR-S
SNVLAAVVFEHTFNHSRDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSA--DGGEPGYIREGFLAVQHAVDRAIMQYHANASTRQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKLK-----------
----------------------------EYMRMMGLSGWLHWTAWFLLFFLFLLIVVSFM
TLLFCVKVK-KD----VAVLAHSDPSLV----------------------------LVFL
ACFAISSISFSFMVSTFFSKV---------------------------------------
-----------------------TGIQWQDLLSPVNVDDDFSFGQVLGMLLLDSVLYG--
LVTWYVEAVLPGQFGVAQPWY-FFI------MPSY-WFGEKSEAKK----ETREIYKITG
SKYFEAEPSDLVAGI-QAKH-LCK----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXX--XXXXXXX

PF00005 // ENSGT00760000118965_2_Domain_1 (796, 959)

LCLP-TNGEAYVNGYDISKQMVQIRKSLGLCPQQDLLFNYLTVSE
HLYFYSVIKGIPRKM-RLTETNKMLSTFNLLKKRN--AQCHSGGMKRRLSIIIALIGDSK
---V-VILDEPTSGMDPASRRATWDLLQHYKQGRTIFLTTHYMDEADILGDRIAIMVEGS
LRCCGSSVFLKKI-YGVGYHIIMVKEPHCDIEEISK---LIYYHIPTATLE---KNVRNE
LSFILPKEYTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--XXXXXXXXX
XXXXX--XXXXXXXXX-XXXXXXXXXXXXXXXXXX-----------------XXXXX---
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXX---X--XXXXXXXXXXXXXXXXX--XXXXXXXXXX-------XXXXXXXXX
XXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X
XXXXXXXXXX-----------------------------XXXXXXXXXXXXXXXXXXXXX
XXXXX-----XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX---------XX--
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXX--------
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXX
XXXXXXX--------XXXX--------------XXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-------XX-XXXXXXXXXXXXXXXXXXXXXXXIPYQENFYAWSTS
GVGRF--VTSMA---------------ASGFATLILLFLIETDLLGRLKTCLFA------
-FRR----RRALTEVYTQTAALPEDQDV-----ADERNRILAPSL--DSLLDTPLIIKEL
SKXXXXX--XXXXAVRNISLLVQKYE

PF00005 // ENSGT00760000118965_2_Domain_3 (1827, 2006)

-CFGLLGLNGAGKTTTFKILTGEETTTSGVVLID
GISITENIRKVRQ-QIGYCPQFDALLDHMTGRETLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSAGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIII--TSH----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MVV
LRQFRLLLWKNYIL---QKRQILVTVIEVCLPLLFAAILIALRHRVHSVSHP--------
----------------------NATLYPS--ESLHDLPSFFSSRH---AS--SPWELAYV
PSN--SSAVRGIAEAVERAL-------PINIRAQGFPSER-------DFEDYVRLDNR-S
GSVLAGVVFRHRFPHSAAPLPLQVEYELRFKYSPRNAPRSEQTGLNPNLDRDWHTSYLFP
LF-QLPGPREAKFA--DGGTPGYLREGFLAVQHAVDRAIMQYHAAASSASLLDNIT-VVV
QRFPFPAYVNDLFLLAIQNQLPLLLMLSFTYTSLNIVRAVVHEKEKKL------------
---------------------------KEYMHMMGLSNWLHWSAWFLMFFLFLLVSVFFV
TVLFCVKVS-EQ----GAVLTNSDPTLV----------------------------FTFL
AIFSISSISFNFMVSTFFSRA---NVAAAAGGFLYFFSYIPYFFISPRYDLMSHSQKLAS
CLISNVAMAMGAQLIGMFEGK-GTGIQWRDLMKPISVDDNFTLAQVLGMLLLDSVLYG--
LVAWYVEAVFPGEYGVPQPWY-FFL------TPSY-WCGRPRTVVGKEKEEEEDPEKALK
SQYIEEEPADLVSGI-KIKH-LSKVF-KVGNKTKEAVKDLTVNMYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLHSP-TGGQAYINGYEISQDMVLIRRSLGLCPQHDVLFDSMTVEE
HLHFYAGLKGYPPSK-CPEEINHILRILSLEDKRRSLTKALSGGMKRKLSIGIALIGDSK
---V-VMLDEPTSGMDPASRRATWDLLQQQRSNRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKRK-YGAGYHMVMVKEPYCNLGEISR---LICQYVPNATLE---SNAGAE
LSFILPKESTHRFE---A-LFTELEQRREELGIASYGASVTTMEEVFLRHRVGKLVDSSM
DIQAI--QLPALQYQH-ERRSNDWAMDDSS-------------SLSGMT-DMTDDSGAL-
----ITEDCSSIKLNTGFYLCCQ-QFYAMFMKRAMYSWRNWKMVA-AQFLVPLIFTAFAL
VVAKTFPGP-----RDSSLLRLTLDPYGQTVV---PFSVSGGAA-------LPQRLADQY
AELLDAQRQSPLE-VL-----GGLEEYLISRASEEGGAFNEHYIAAASFEDVGNRTLVTA
LFNNQAYHSP-----------------------------ATALMLADNAILRVLAGSNAS
ITVTNYPQPRNITEKAKDQ-LME-----GQTGFAIAINLLYGMASLA---------ST--
FALLLVSERAIKAKHVQFVSGVYVVNFWLSALLWDIINFLIP-----CALML--------
VIFQAFNVQAFTQDSHLVD-VMLIFLLYGWAIIPLMYLLSFFFSVAATAY------TRLT
IFNILSG--------TATFLA---VTIMSIPELGLVDLS-KTLDKVFLVLPNYCLGQCIS
DFYQ-------------NYEFIQ-FCTSSVEAIF-------ICKAFNISYQMNYFSWETP
GIGRY--LTSLA---------------VQGFSFLFLLFLIETNLLWRVRTLLCGI-----
-CRRR---K--WVALLNRVSVLPEDRDV-----ADERKKVLESPPELLSSLSSPLVIKEL
TKVYDSR--ESLLAVDRISLAVSKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGDESITSGDAFVD
GHSILANIKKVQQ-RIGYCPQFDALLEHMTGRETLSMYARL-RGIPERYGGSCVENMLRG
LLLE-PHADRLVRTY---SGGNKRKLSAGIALI---------GGPPVIFLDEPSTGMDPV
ARRLLWDAVTRTRECGKSIIF--TSHSME----ECEALCT-----RLAIMVNGQFKCLGS
PQHLKSKFGSGYTLLAKTRGE--------EE---GELQAFKAFVEKT----F--------
-P-GSVL-----KHEHQGMVHYHLTNKNLSWAQ--VFGALEKAKEKYRLEDYSVSQISLE
QVFMSFTRFQHYTEDRGK------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------NG--
FCLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1445, 1715)

TVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
GVIKYRKLDIYVTDYHILE-TMLIFTLYGWSAIPFVYLISFVFSGSTSAY------IKLL
LLSYFSG--------TFGFLIG--EIIENKKLTNISNTTRTVVRNSLLLFPNYNLAKCVS
QYTT-------------IYDVKI-LCTTLKK-HPVHLN----CSKA--NTEKNIYSLKEP
MIGKY--LIDMS---------------TAGFIFL

ENSGT00760000118965_2_Linker_2_3 (1715, 1815)

VLIFFWETTS-WRLRTFLNQYIYFG-
IYKRYRKE---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLDSIVLVKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIKLYVNKWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSIIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLQDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------VKYHLRFRNLNALNNSLH--PLIGSHNIDWDTSILFP
II-PSIGPRNPLEA--DGGYPGYIREGFLAVQHSLDKAIMIYHNGRAAERMFDNVI-ILA
QRFPYPAHYQDKYLMLFLVIFPWLAVFIFSLSELPLIRNITSEKQKKLK-----------
----------------------------DYQLITGLTNFMIWAAYFIAGLLMFIIIVCAI
CMTLCLKIV-R-----DRILQYSDPILI----------------------------VIFF
LSFVIASILFGFMISTFFNRA---AFAVAAGSFLYFLKFP-VT--FTSKNSASLSVKLFS
CLSLNTALTMGIETLVKMEMK-RDGVQWNNAFSPVNQDDNITFAHITGMLLIDAILYG--
LLAWYVDAVFPGKYGVPKPWY-FFL------QSVD-WFHSRSLLSTQS--QVK---SLLL
SPCMDAKKLSLVHYLAVRQH-LYYEF-TLHNTKII-AADLSLNLYE---GQITVLLGP-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTSLLPF-TRGKVCINGYDISTNTIQARKIMGFCPQDNLLFKKLTPSE
HLYFYSVVKGVPPEK-RSIEIKKVLTDFGLLHVCNVLSMNLSGGTKRKLSLSIALLGDSK
---V-VILDEPTAGMDPVSRRATWDILQQYKESRTILLTTQQMDEADILGDRIAIMVKGT
LRCCGSPVFLKRK-YGVGYHVIMVKKPDCDIENIVQ---LINQHIPTASLE---SNVASE
LSFILPKEYTQRFE---A-LFIELEKRQKELDIAGFGVSITTMEEVFLK--VSYLSEFKE
DKQSLL-KSPSLMDQNTGEDKNR-DMNVPGGE------------------RI----Y---
--HHTLNEDSNVMLNTGCTLYIQ-QFYAMLVKKAIFTRRNWFVVL-IQVLGLLGMSYITI
GNFNLDMNIFKRKYNDEPARKMDLEQYGQTIV---PVSISGHSD-------LTQNFTKHL
KIMLKAKKQKLQE-VQ-----GDLQKYL-----VESQECFYSCIIALSIEVTRNKKKFTF
WFNNEAYHSP-----------------------------SLSLAVLDNIIFMSLSGPDAS
ITVSNKPQPQFTTLVKD---KEK-----KMKGISISFNLLTGISILV---------SG--
FCFLTVTERVNNVKHMQFLRGIYVLNFWLSTLLWDLFIYFIA-----CCLLL--------
VVFIFIGLHILIEDYHFLD-TLFIFLLFGWSNIPIVYLISFLFSSSTTAF------VKIF
LINQFLG--------ILTLLPYSMLLKN----GVILYSTKKSIMNALLPFPIFNFGVSIS
KYYN-------------FQEEKI-SCFSSKN-VSNSTRPKSLCLSS--VIKLNTYSLEES
AIGQN--VIAMA---------------ALGLIFMFLIYLLETTL-WRVKTFVLRYIFFG-
IYKRFYKD---KVSLE--LPEVSKDEDV-----QNERGRVLEQRQ---ELLNSPVFIDEL
TKIYFTF--PPIVAIRNISLAIQKED-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKILTGVETPTSGDLFME
GLSITKNILKVRS-KIGYCPQYDALLHHMTARETMIMYARL-RGISETKINLYVNNFLKM
VNLE-FHADKVINTY---STGTKRKLSAAIALI---------GNSPIVLLDEPSTGMDPI
ARRLLWNTVIQARESGKIIII--TSQSME----ECDVLCT-----RLAIMVQGKFVCLGS
PQYLKNKFGNIYSLKVKFNT-------DTIE---NIIEDFKTFIVHV----F--------
-P-GSVL-----KHKNQRILNYYIPRKDNGWGK--VFGILEKAKNQFGIEDYSFSQITLE
QVFLSFANQDKTARDYER------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRSFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHADAATHQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGIPQPWY-FFI------LPSY-WCGKPRAVAGKEE-EDSDPEKELR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKERAAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYVSGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHDHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEEHTAVKLNTGLTLHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SVLLL--------
VVFKAFDVRAFTQDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIENNLLQRLRGILCAF-----
-RRRR---T--LTEFYTRMPVLPEDQDV-----ADERTRILAPSPDCL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-QIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSFC----TGWAMEEPGGQEILWHPQPWQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEDFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYSVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAL
FRQFTLLLWKNYTL---KKRKIVVTVLEILLPLLFSGILIWLRQNIHSENIP--------
----------------------NATIYPG--QSISDLPLFFNFPP---PE--DSWELVYV
PSN--SEAVKTITEMAKKTL-------VIDMKVRGFPSEK-------DFEDYIKFNNH-S
YNVLAAIVFEHNFNYYKEPLPLEVKYHLRFSYFRKNDMWAGMTFFFPREIEGWHTTSLFP
LF-PNPGPREPSFP--DGGEPGYIREGFLAVQHAVDKAIIQYHASTAATRLFEKVT-IIA
KRFPYPPFISDSFLVAIQYQLPLLLMLSFTYSTLTIIRAIVQEKERKL------------
---------------------------KEYMRIMGLSNWLHWSAWFLTFFLLLLFTIFFM
TMLFCIKVE-ED----IAVITNSDPSLV----------------------------FVFL
MCFAISSISFSFMVSTFFNKA---NLAAAIGGFLYFFTYIPYFFIGPRYNWMTLNQKLSS
CLFSNVAMALGAQLIGKFEAK-GIGIQWKYLMKSVNVDDNFTFGHVLIMLLFDSAFYG--
LVTWYVEAVFPGEYGMPQPWY-FFL------MPSY-WCGNQRSSIGKEE-EDDDPEKVLK
TEYIEAEPEDLVAGI-KIKH-LSKMF-MVRNKRKEAIRDLTLNMYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTGLFPP-TSGRAYINGYEISHDIVQIRKSLGLCPQHDVLFDYMTVAE
HLYFYAQMKGLSEQK-CPEEVNHILNILDLENKRHSLSKSLSGGMKRKVSVGIALIGGSK
---V-VMLDEPTSGMDPISRRATWDLLQQQKNDRTIVLTTHFMDEADLLGDRIAIMAKGD
LQCCGSSLFLKHK-YGAGYHMIIVKELHCNTSEISR---LVYHHIPNAILE---SNVGAE
LSFILPKESAHRFE---I-LFTELELKQKELGIASYGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAMDN---------------NLSGIM-DLTDSIGAL-
----IKEDCTSIKFNTRFYLHCQ-QFYAMFTKKTLYSWRNWKILV-AQILVPLTCITLAL
MAINYSSAI-----RDDPILQLTLDQYGQTIV---PFSIYGTSK-------LDQQLSERF
KDMLQAEKQVPRE-VL-----GDLEEFLIFRASVEGEGFNERCLVAASFKDVRDQTVITA
LFNNQAYHSP-----------------------------ATALAIVDNILFKLLSGPSAS
ITVSNYPQPRGASQTTTEQ-ADE-----GHTGFHLALNLLFSMAFLA---------ST--
FSILAVIERDMKAKHIQFVSGVYVIHFWLSALLWDLLTFLVS-----CSLLL--------
VVFRAFNVEVFTQDNHLAD-ALMILMLYGWSIIPLMYLMSFFFSGAAAAY------TRLS
IFNILSG--------LATFLI---ISILRMPGLKLLQLS-KTLDMVFLALPSHSLGMSIS
NFFE-------------NFETKK-YCTSSEIAAH-------NCKKFNIKYQENFFAWKAP
GIGKY--MTSMA---------------VSGFVFLILLFLIETNLLWRLRTLVSGI-----
-FRTR---N--WAQMHVQAPVITKDQDV-----EDEKKKVLESLPEL--LLNTPLVINDL
TKVYSQR--MPFLAVDRISLTVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEDTITFGDAFVD
GYSIITDIKKVRQ-RIGYCPQFDALLEHMTGRETLIMYARL-RGIPEGHISNCVKNVLQG
LLLE-PHADKLVKTY---SGGNKRKLSTGIALI---------GEPSVIFLDEPSTGMDPV
ARRLLWDTVTRARESGKAIVI--TSHSME----ECDALCT-----RLTMMVNGQFKCLGS
PQHLKSKFGSGYTLLAKVKS----DRQEGKM---EALELFKMFINQT----F--------
-P-GSIL-----KDEHQGMVHYHLPSKDLSWAK--VFGILEKAKEKYGLDDYSISQVSLE
QVFMSFAHLQSSGEDER-------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTDSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMEYHADAATRQLF

PF12698 // ENSGT00760000118965_2_Domain_0 (353, 658)

QRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PN----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWQRPPESRQRGRRLLLWAGAGMLLLDSVLY

ENSGT00760000118965_2_Linker_0_1 (658, 758)

G--
L------PVFPGQFGVPQPLV-LFI------MPSY-WCGKPRAVAGKEE-EDSDPEKALR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEDISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEERTAVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVASFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFLGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDRVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVATH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLQRLRGILCAL-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLPYSP---TWHPPRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYGVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

-------PP--VAAWRLGLHARSFRNVVPLCPGPCGVFLSFRPLPSLAVLSIPPGKRMAV
LRQLALLLWKNYTL---QKRKVLVTVLELLLPLLFSGILIWLRLKIQSENVP--------
----------------------KATIYST--QSIQELPLFFSFPP---PG--DAWELAYI
PSQ--SDAVKTITETARRAL-------VINMRLRGFPSEK-------DFEDYIKYDNR-S
SNVLAAVVFEHTFNHSKDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTSSLFP
LF-PNPGPRERTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHANASTNQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWTAWFLLFFLFLLIAVFFM
TLLFCIKVK-KD----VAVLTHSDPSLV----------------------------LVFL
ACFAVSSISFSFMVSTFFS-----------------------------------------
--------------------K-GTGIQWQDLLSPVNVDDDFSFGQVLGMLLLDSILYG--
LVTWYVEAVLPGQFGVPQPWY-FFI------MPSY-WCGRPRTVLGKEE-EDDDPEKALR
TEYFEAEPEDLVAGI-KIKH-VSKVF-RVGNKGKAAVRDLNLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYINGYEISQDMVQIRRSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHILSLEDKWDSRCRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPTSGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPESISQ---LVHHHVPNATLE---SSAGAE
LSFILPKESTHR-E---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGTM-DPTDGIGAL-
----IKEECTAVKLNTGLTLHCQ-QFWAMFLKKVTYSWREWKMVV-AQVLVPVTCITLAL
LAINYSSI------FDXXXXXXXXXXXXXXXX---XXXXXXXXX-------XXXQLSEHL
KDMLQAEGQDP-E-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGEQTVVTT
LFNNQAYHSP-----------------------------ATALAIVDNLLFKMLCGPRAS
ITVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHIQFVSGVHVATFWLSALLWDLISFLVP-----TLLLL--------
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXTAY------TRLT
IFNILSG--------IATFM----VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETKR-YCTSSEVAAH-------YCRKYNIQYQENFYAWSSP
GIGRF--VTSMA---------------ASGFAYLTLLFLIETDLLWRLKTCICAF-----
-WRRR---A--LMEVYTQPSGLPEDQDV-----ADERNRILAPSPRSP--LDTPLVIKEL
CKVYEQR--APLLAVDKISLAVQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RIGYCPQFDALLDHMTGRETLIMYARL-RGIPERHISAYVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSNGMDPV
ARRLLWDTVARARESGKAIII--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------DGQQ---EALEQFKAFVDLT----F--------
-Q-GSIL-----EDEHQGMVHYHLPGDNLSWAK--VFGILEKAKEKYRVDDYSVSQISLE
QVFLSFAHLQPPAEDEGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNWLI
VNQLTVLLWKNFTL---KKRQMISSVTEIMAALLFVIMLLIFRAFTG-INVV--------
----------------------GPYHFTP--QPIATMPSFIKDA--------KEWELIYT
P-D--IDVVSEIIENVKKNL-------NTTIKVRGFPSEA-------AFEEYILFDYT-S
QKVLAAIVFDCGFKNKNDPLPLQIKYYLRFVGVQRTIL--------WPDKTGWKTTFLFP
NH-PSLQPRNPNFP--DGGSPGYIREGFLAVQHALDMSIMLYHESNAG

PF12698 // ENSGT00760000118965_2_Domain_0 (349, 593)

KKLFDEIN-VLI
QRFPYPAHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIIGLRNWIIWAGYFFTFFPLYAIIILLI
CALLFI----AE----EPILRYSDCSFI----------------------------FVFL
ICYAIASICFAFMVSTFFNKT---HLAASAGNLLFFASFFPYNFISEHYGLL

ENSGT00760000118965_2_Linker_0_1 (593, 805)

DLTSKMTA
CLSANVALAIGINVLIKLEIQ-EIGVKWHNLWTPANLEDNLIFGYMFGMLLFDAFLYS--
LVTWYVEAVFPGQCGVPQPWY-FFL------MRSY-WFGKPKIRKT-A--E-ETKCLPTI
HNSFEAEPTNLVAGI-QIKR-LH-------------------------------------
-----------------------K

PF00005 // ENSGT00760000118965_2_Domain_1 (805, 912)

AYINGYNISDNMIEIRKDLGFCPQHDLLFDDLTLSE
HIFFYSKVKGIHQNI-NYMEIDRMLSIFNLKDNFHTLSGSMSGGVRRKLSIIIALTGGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1183)

SSGLDPISRRATWDILQHYKHNRTILLTTHYMDEADILGDRIAIMVRGT
LHCCGSSVFLKQI-YGAGYRIVMEKEPYYDINNIFA---LIQHHVPSAVLE---NDLGSE
LSFILPKMYVSRFE---T-LFTELEINQKTLGIANFGASITTMEEVFLK--VNKLAAPQR
NTQAI--KPYNFTYGK-MRQDKQQNVNIPRNY------------------NRPN------
--FPYLSEIATIKFNTGFPLYRQ-QFCSMFIKRALFIWRNWK

PF12698 // ENSGT00760000118965_2_Domain_2 (1183, 1718)

LML-LQIIVVLVVTTYLL
LALHLD-------DDDIPERELDLSHYGRTIV---PYSISGNSD-------LALNLTKNL
KIFLKSKNQSLRK-IK-----GDINDYI-----LESKECRSFCIIALSIKIEKNKTVLTV
FFNNEAYHSS-----------------------------AISLAVLDSILFMTLSGPNAS
ITAFNKPQPQ--PYYGSNT---V-----PINGLQIVQCLAFGISVVV---------GT--
FSLQTVTERISQAQHIQLLSGVCVLSYWLSALLCDLIFFFIP-----SCILL--------
GIFRFCQVDAFVVSYNFLD-TMLIFMLYGWCVVPLTYLGSFLFHSSTTAY------IKLT
LFNYFST--------IFSIVIYTIVQFYG---SDFPNFITYIVKSALMILPSYNFAMSIS
KYFD-------------DYEVKT-LCAREF--KSIYMD----CSEP--YTQNNVYGFGEH
GIGKF--LITLA---------------VMGLVFFLLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

LFLETVS-WNLKNFVFHNIIFY-
FYNKIREGRQAVVSNQ--GTKEDEDEDV-----SQERRKVLTLLS--LKSQDTPLVLNEV
TKIYFKC--PVVKAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1975)

RNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGVALID
GNSVIKNPRKIRS-RIGYCPQSESVLNHMTGRELLSMYSRL-WGVPEQNINEYVEAFLYS
VQLE-PIADQLIHTY---SGGNKRRLSTAIALM---------GKSSVVLLDEPSAGMDPV
AQHLLWDTVSWVCKTGKAVII--TSHRME----ECETLCT-----RLAIMVKGSFTCLGS
PQHVRKRFGHVYTLTVKINI-------AKDR---DKVAEFNQFIKTT----F--------
-P-GNIK-----NQEFQGIIGYYIPSKEICWGK--VFEIMEKAKVLFNLEDYSFKQVTLE
QIFLTLANTDKRR-----------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MVSLR
MKQFSVLLWKNLLL---KRRNVVGLVVEILLIFLLFAWTLTMRKITK-KTFT--------
----------------------QAVIFNP--IPLT-LPEFVN------KK--FEYEL

PF12698 // ENSGT00760000118965_2_Domain_0 (178, 665)

AYV
PSG--SDAARNITEMVKKDL-------NFNFKVRGFSSEE-------SFEKYIKYENK-S
SYVLAAIVFEHMFKTNSERLPLQVKYNLRFGHLYNPNNPLE--PSEDQKGKDWNTSILFP
SE-PSLGPRRSSED--DGGHPGYIREGFLIVQHSLDKAIMVYHSGRAAEDMFANTT-IYA
KRFPYPASIRDRFLWAFIFMFPWTILFTFTQMSLVIVGTIMLEKEKRLK-----------
----------------------------EYQLMVGLSNAMLWVSYFVTFLLMYFIIICLL
CGILFLKIT-H-----ERVFEHSDPLFI----------------------------AFYF
LCFATSSVLLGFMISTFFDKA---SLATSIACFLHFLTFFPYLIILPIYEQTSLGGKLAL
SLITNTALAFGADIICKMEMK-GDGAQWYNFATKIKADDDLTLAHIIGMFLLSAFLYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMDAVFPGKYGVPKPWN-FFL------QKAY-WFGEQASD--K---EESQITDLPT
NDFVEPEPIGLEAGI-RIQH-LYKQF-TLKNSTLMAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSILTGLYLP-TRGKVYISGYDISSDMVQIRKSLGLCPQDDLLFPMLTVSE
HLHFYYVIKGISPNE-RYREIHRMLTSFGLLQKRDAMSKDLSGGMKRKLSIIIALIGDAK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1190)

SGMDPVSRRTTWDLLQQYKENRTILLTTHHMDEADVLGDRIAILVMGS
LKCCGSSLFLKKL-YGVGYHLVMVKTPECNVEKISK---LIRDYIPTAEMK---TDVAAE
LSFVLPKDYTHRFA---E-LFRVLEEREEELGITGFGVSMTTMDEVFFK--VSNLADIKM
NTEIV--QPASTVDR--SMSEANQNMNVPRNF------------------DRS-------
--DY-PRGHSNSSFSTGWALYTQ-QFRAMFIKRAMFSWRNWKLLV-LQL

PF12698 // ENSGT00760000118965_2_Domain_2 (1190, 1718)

LALLGLMYLLM
KGISFS------T-PKKPARVMDLEQYGETIV---PFSVSGDPV-------LTQKLTKNL
EIMLKAKNQKLHE-VQ-----GDVQTYL-----LANEDCIYSCIIAFSLDVTRDQKKFTF
WFNNEAFHSP-----------------------------SLSLSVLDNIIFMSLSGPNAT
ITVSNKPQPQR--EKKS---EKR-----GSSGIQIVFNLLFGMSIFT---------SG--
FCLMTVTERVSKAKHIQYVSGVYTLNFWLSALLWDLVIHFVA-----CVLLL--------
LVFLITDVDILLEKYHFLD-TMFILMMFGWSVIPFIYLLSFRYNNSTSAY------IKIF
ILNHCLG--------FMSIIIYDVVEII----PDITTRTKTFIVDSLLLLPIYNLGMSIF
KYHH-------------IQNMKK-WCSSQNV-TDTDLC----L-NK--IMKISIYSMDKN
AIGRH--MTAMA---------------ATGVLYLLLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLLEFSV-WNLKTFIYRYVFFG-
IYKIFSKA---RVSRE--LSGESEDEDV-----QNERKTILKYPQ---KALDSTVLIKEL
IKIYFKI--PPTLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISVTIQKEE-CFGLLGLNGAGKTTTFEILTGEEIATSGDVFIE
GYSITKNIRKVRS-KIGYCPQFDALLDFMTSREILTMYARV-WGVPEKNIRPYVDNLLEM
LYLQ-PQAEKFIYTL---SGGNKRRLSAAIAIM---------GKSSVVFLDEPSTGMDPL
ARRMLWNTVIRTRESGKVIII--TSHSME----ECEALCT-----RLAIMVQGKFMCLGS
PQHLKNKFGNVYTMTIKFKS-------GTGD---KVITDFKKFVTNA----F--------
-P-GSDL-----KQENQGILNYHIPSKDNSWGK--VFGILEKAKEQYNLEDYSISQITLE
QVFLTFANPDNIESGSAKAKS-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

ILELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPE--QSIQQLPLFFSLPP---PG--GSWELAFI
PSH--SDAARTITETVRREL-------VINMRVHGFSSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHAFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGNIFLRETEGWHTTSLFP
LF-PSPGPREPSSP--DGGEPGYIHEGFLAVQHAIDKAIMHYHANASAHQLFQKLT-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLSIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFFLIMVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NIAAAVGGFLYYFTFSPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLNPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVIGKEE-EDSDPEKTLR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKDKVGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSMLTGLFPP-TSGHAYIHGYEISQDMIQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGMSLQK-CPEEVKQMLHILSLEDKRDLRSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKNDRTILLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LIHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGAL-
----IEEEEAMLKLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPVTCITLAL
LAINYTSES-----LDDPPLKLSLDEYGRTVV---PFTVSGTSQ-------LHQQLSEHL
KDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDSGEKTEVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEISNYPQPRSTLQVAKDQ-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVQAKHIQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFQAFDVQAFTRDGHLAD-LLLLLMLYGWAIIPLMYLTSFFFSAASTAY------TRLT
IFNILSG--------IATFIV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCVGMAVS
SFYE-------------NYETRR-YCTSSWVAAS-------YCKKYNIQYQENFYAWSTP
GVGKF--VTSMA---------------VSGCIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-QRRW---T--LAELQNRTSVLPEDQDV-----ADERSRVLVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSEIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLISACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTAIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---EVLEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MTV
FRNLKLLLWKNFIL---KKRKILVTVLELLMPLLFSTIVMYLRFNSL-PRMK--------
----------------------PPVNYTA--IDISLLPEFFYNFP---VK--NNFQLVYV
PSE--SETLKALTEMVEKSF-------DVDFEVLGSQSVS-------SFDKYIIKDSK-S
FYVLAGIIFDNSFKKRKKPLPLSVKYHLRFSYIKRNYLLSR-LIFFRDDGEGWSTNYLYP
PN-PGQEPREYLFD--DGGLPGYYKEGFLAIQHAMDKAIMWYHAHDAMTEMFESVS-VLV
KRFPCGAYVQDSFFLILQNEFSLLLMLSFMKADRKLSQPYYQEDQPKVK-----------
----------------------------DYMRMMGLNNWLHWVAWFIVFFLSVLIAVSVM
TVLFCTEVH-N-----VAVFTNSDPSLV----------------------------FVFL
MCFAIATIFFAFMTSTFFKKA---HVATAAGGVIFFFTFLPYLFIAFTYTWRSQSQKIAS
CLFSNVAMALGVRLISIFEAK-GAGIQWHNIG---SLNGDFNFTQVLLMLLLDSFLYG--
LVTWYVESISLGEHNASKPWY-FFV------MPSY-WHREPRTLISPT-LEMGHPEEPLK
SKFIQNEPTDLMKGV-EIHH-LYKVF-HVGGSKHTAVRDLTMNLYR---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TCAVLTGLCAP-SSGQVYINGYEISQDMVEIRKSLGWCPQHDILFDNLTVAE
HLYFYAQLKGLPRGK-CPEEVEQMLHILNLEDKQHSKSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPTSGMDAVSRRAIWDLLQQQKSERTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKKK-YGAGYYMTLVKESQCDVETISH---LIYDHIPDAILE---DDAGEE
LTFVLPKESVHRFE---S-LFTELEMRQTELGIASFGASVTSIEEVFIR--VNKLVDSNT
DIQAI--KLPPVQSES-LVD---------RVPVDR-------IK--RFHSRI--------
--FSLK-TGLQIIPNSGFSLLCQ-QFYAMFLKRVTYSWRNWMMILSIQILVPLVIVIFSL
IAFSLSTKN---L--ETIPLDLTLKTHGESIV---PFFISQNSR-------LDPQLSKHF
ADMLVKDGHTPME-IL-----GSIDEFLLTKAEDEPESFDNRYVVAVSFEDVKNHTVVTA
LFNNQAYHSP-----------------------------AMALTLVDNFLFKLLSGEGAS
ITVYNHPQPMSSQETSESI-LYQ-----GPKGHYLVINLVFGMAFLS---------SS--
FCILTVKERSTKVKHIQFVSGVYVVTFWLSALLWDLISFLIP-----SLLLM--------
VVFLYYNEEAFIQDGNLTA-VFLILMLYGWAIIPFIYLASFCFGNPGSAC------VKLI
IMLTFLS--------ICPI--IL-VTVTIITDLGYTTIS-ESLDDAFLVLPGHCLGMAFT
NLYY-------------NFELKK-YVTRSEVAG--SYEK-----KKGYVIQKNIYAWESL
GIGKY--LTTLS---------------ILGPVYIVLLFLIETEALWKLKAK-VSD-FCR-
--RKD---L---A-ELLDVALVPEDEDV-----AVEEKTIQSNMEKLC--ENNPLVIKEM
SKVY-FK-QTPLVAVKHVSFVVRGNH-CNGISGCDGFKSGAAYMELMQQDDATKRDAVSR
CHQGCKWA

PF00005 // ENSGT00760000118965_2_Domain_3 (1869, 1974)

QKVRR-QIGYCPQFDALLDHMTGRETLVMYARL-RGVPERHIAACVEQAIED
LALR-TYAEELVKTY---SGGNKRKLSAGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWGTIARVRKSGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRG-------N-RQ---ETLRKFKAFMDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPSHGLSWAK--VFGTLERAKEEHSLDDYSVSQITLE
DIFLSLNRPSSKKREFH-------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MSV
LRQLALLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

ILELLLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPS--QSIQQLPFFFTLAP---SV--GTWELAYV
PSH--SEAARTVTETVKRAL-------QVNIRVRGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHVFNHSKDPLPLAVKYHLRFSCARRNYIWTQTGNFFLKETDGWHTNSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLVVQHAVDKAIMHYHANASTQQLFQKLT-VKA
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRSVVQEKERKL------------
---------------------------KEYMHMMGLSSWLHWTAWFLMFFFFLLIAVSFM
TFLLCIKVK-KD----IAVLSSSDPSLV----------------------------LVFL
LCFAISSISFSFMVSTFFNKA---NIAAAVGGFLYFFTYIPYFFVAPHYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGSPRTVVGKEE-EDSDPEKALR
TEYFEAEPEDLVAGL-KIKH-LSKVF-RVGNKDKAVV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSVLTGLYPP-TSGRVYISGYEISQDMALIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSPQK-CPEEVKHMLYALNMEDKRNSPCKYLSGGMKRKLSIGIALIAGSK
---L-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1410)

SGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMADGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEAISQ---LVHRHVPNATLE---SHAGAE
LSFILPKESTHRYV---P-RRTHRCR----------------------------------
---------------------------------------------CGKA-R---------
-----------------------------------Y------------------------
-------EL-----VRRPPLVLWLS--GRVL----------------------ALITKKL
RDSSQAQSSSP-------------------------------------------------
------------------------------------------------------------
---------R--TDTLCSA-LPR-----G

PF12698 // ENSGT00760000118965_2_Domain_2 (1410, 1718)

RKGFDIALNLLFAMAFLA---------ST--
FSVLAVSERAVQAKHVQFVSGAHVATFWLSALLWDLLSFLVP-----TLLLL--------
VVFRAFDVRAFTRDGHMAD-LLLLLLLYGWAIIPFMYLMSFFFSSASTAY------TRLT
IFNILSG--------IVTFIM---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRQ-YCTSSEVASH-------YCKKYNIQYQENFYAWNTP
GVGRF--VTSMA---------------ASGCAYLSLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFICAF-----
-QRRW---T--LAELHSRTSVLPEDQDV-----ADERNRVLAPSLES----HTPLIIKEI
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIQQVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGPCVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVHS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGQDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTVEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LKKLKLLLWKNFIL---KRRKTLITL

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 664)

LEMLMPLLFCAIVLYLRLNSM-PRKK--------
----------------------SSTNYPA--VDVSLLPVYFYNYP---LK--SKFQLAYI
PSK--SETLKAVTEVVEQTF-------AVDFEVLGFPSVP-------SFEDYIIKDPK-S
FYILVGIIFHHYFNSSNDPLPLVVKYDLRFSYVQRNFVSPPRHLFFQEEIEGWCTAFLYP
PN-LSQAPREFSYA--DGGNPGYNKEGFLAIQHAVDKAIMRHHTPQAALNMFRNLH-VLV
QRFPLGPHIQDPFLVILQNEFPLLLMLSFVCVELIITNSVLLEKERKQK-----------
----------------------------EYMCMMGVESWLHWVAWFITFFVSVLITVSVM
TVLFCTKIN-R-----VAVFRNSNPTLI----------------------------FIFL
MFFAIATIFFAFMMSTFFQRA---HVGTVMGGTVFFFTYLPYMYITFSYHQRTYTQKILS
CLFSNVAMAMGVRFISLFEAE-GTGIQWRNIG---SVWGDFSFTQVMGMLLLDSLLYC--
LVA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

VLVESLFPGKFGIPKSWY-IFA------KK-------PVPAIPPL-LNIGDPEKPSK
GDFMQDEPMNQMNTI-EIQH-LYKVF-YTGRNKRTAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSMNLYK---GQITVLLGH-N
GAGKTT--ICSVLTGLITP-SKGHVYIHGYEISKDMVQIRKSLGWCPQHDILFDNFTVTD
HLYFYAQLKGLSPQN-CHKKIEEMLHILGLEDKRDSRSKFLSGGMKRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1185)

SGMDAVSRRAIWDLLQQQKSGRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYYMTIIKTPLCDTSKLSK---VIYHHIPNAILE---SSIGEE
MIFTLPKKTTPRFE---A-LFTDLELRQTELGISTFATSVTTMEEVFIR--VCKLADPST
NVLTE--KRHPLP-----R------HH--RIPVDR-------IK--CLHSRI--------
--FSVS-TEQPMRLNTGFCLLCQ-QFYAMLLKKVTYSRRNWMLV

PF12698 // ENSGT00760000118965_2_Domain_2 (1185, 1718)

LSVQLLLPLAIVMLSL
TFFNFKLRK---L--DNVPLELTLQMYGQTIV---PFFIAENSH-------LDPQLSDNF
VKMLVAAGQVPLR-IR-----GSVENFLLKKAKEAPEDFDKLYVVAASFEDVNNHTTVKA
LFNNQAYHSP-----------------------------GLALALVDNLLFKLLSGTNAS
ITTTNYPQPQTAIEVSESI-LYQ-----GPKGHYLVVNFLFGIAFLS---------SS--
FSILTVGEKSVKSKSLQFASGVNMAVFWLSALLWDLISFLIP-----TLLVV--------
LVFLWYEEEAFAHHENIPA-VVLIMMLYGWAIIPLVYTVSFSFNTPGSAC------VKLV
VMLAFLS--------ISPV--VL-VTVTSEKDLGYTELS-DSLDHVFLILPGHCLGMALS
NLYY-------------NFELKK-FCNAKNLSDIDCNDV-----LEGYVVQENIYAWESL
GIGRY--LTALA---------------VLGPVYITLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLTEASAFYVLKSR-LSG-FFPS
FWKEK---SG--M-IFDVKEPEDE--DV-----LEETETIKRYLETLI--KKTPLVVKEV
SKVY-NE-KAPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFVVKEEE-CFCLLGLNGAGKTSVFNMLTSEQPVTSGDAFIK
GFSIKSDIVKVRQ-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPECHIKACVDLILEN
LLMC-VCADKLVKTY---SGGNKRMLSTGIALV---------GEPAVILLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVRGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---EVLEEFKAFVDLT----F--------
-P-GSNL-----EDEHQNMVQYCLPDPDLSWAK--VFSIMEQAKKDYMLEDYSISQLSLE
DIFLNFTRPESSTKEKIQQGQAVPASPLPPS-----RPISSPP-SQLSSQPPKPLPSPPP
SEPVLL------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLLW
LNQFAVLLWKNFVL---KKRKILSLVVEICMTVVFSLLILLYRSNTK-KTFQ--------
----------------------NVTVFRP--LYLITPPDFIFK-----GD--LEYELAYV
PST--SDVVKNITETVKNTL-------NINFTVRGFSSEA-------QFEKYVQYEKKPT
VRVVAAIVFDHDFKNSDDRLPLQVKYHLRFGTGTERTS--D--FLSSLVDTGWHTHILFP
EV-PDIGPRNPLSN--DGGDPGYIREGFLLLQHIIDQAIITYHNGEAAERMLNDAT-ILL
NRFPYPAYYMDSFWYSFSALFPLIVILAFSLTELTLIRTIVSEKEKRLK-----------
----------------------------EYQLMIGLNNAMLWASYFVSFFLMFLIIICLL
CVILFVKIA-P-----EVVIQYSDPSLV----------------------------FVFF
LCFVITSISFGFLISTLFDTA---TLAVSVGGFLYFLTFFPYIFMQTIYTQMALTEKLVF
CLLSNVAVALGANIISQMEMK-QYGVQWDNIQSSVSPDDDLRFVHIMGMLLFDAALFG--
LMAWYMDAVFPGRYGVPKPWY-FFV------QKSY-WFG-KALSVKYK--EDKRIIDKIK
SDYFEEEPVDLVAGI-RIQH-LYKEF-TVEKDTIVAVKNLTFNVYE---GQITILLGP-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTGLTLP-TSGKVYISGYDISKDMVHIRNYLGFCPQDDILFSELTVSE
HLYFYCVIKGVPPEI-RATEVNNVLTSFDLLEKRDALAQSLSGGMKRKLSIIIALIGGSK
---V-VILDEPTSGMDPVSRRFTWSVLEQYRYDRTILLTTHHMDEADVLGDRIAIMVKGS
LQCCGSSIFLKRI-YGVGYHIIVVKEPHCNVEEIIE---VIDQHIPEARLE---SDVAAE
LSFILPKKYTHRFK---D-LLTDLENRQKELGISSFGVSITTMEEVFLR--V-----IRK
DEEA-F-QTPSLKEKNRREDMNQ-NMNASGSF------------------ER---YS---
--PT-ASEHSNIRFNTGWSLHWQ-QFYAMFIKRAMFSWRNWSLSL-MQILGLLGIVYFLM
KVEKIS------RNTIEPAREMDLEQYGQTTV---LFSDDSHSD-------FSQNLTKIL
DIMLKAKKQKLQE-VK-----GDLQTYL-----QDSQECIYSCIIAISFR---DQKVVTL
WFNNMAYHSP-----------------------------PLSLAVLDNLIFMALSGPDAS
ITVSNKPQPQNIVSKKL---EGR-----KIPGQQVALNLYLGVSIFV---------SG--
FCLLTVTERINKAKHIQFVSGVSAINFWLSALLWDFMIYFIA-----CCLLL--------
VVFLLSGLDELTKNYRFLD-TLIIFLLFGWSVIPFTYLISFLFSSHTSAY------IKLV
MLNYFAG--------VFGIVLESVITT------S-GSGSESLLLDSLMVLPIYNFGMSIS
KYFN-------------NQNTRL-LCSSK-D-VPAFIN----CSKA-I-TEMNVYGLEKD
AIGKF--LIAMA---------------VLGFIFFVLIFLLETTS-WKVKTFVFHYIFFG-
IYKKFNKE---IVSTE--LSGESEDDDV-----QAERNRILEQPQ---ESLNFTVLIKEL
TKIYFTC--PAVLAVRNISLGIQKKE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKILTGEETATSGDVFIE
NLSITKNLLEVRS-KMGYCPQFDALLDYMTAREIMVMYARL-WGVPETQITQYVNKLLQS
LNLE-LYADKFIYTY---SGGNKRGLSNAIALM---------GKPSVIFLDEPSTGMDPM
ARRLFWNTITRARESGKVIII--TSHSME----ECDALCT-----RLAIMVKGKFRCLGS
PQHLKNKFGSVYILKVKLKM-------DTDE---NELEDFKTYIATV----F--------
-P-GSEL-----KQENQGILNYYIPREDNGWGK--VFGILEEVKEKFSLEDYSISQITLE
QVFLSFASPENKGGD---------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDTLW
LNQFAVLLWKNFIL---KKRKMASLIVEISMTVLFCTLILLLRKHST-RELT--------
----------------------QATFFRS--LPLNELPTFLTN-----KK--KEFELVYV
PSG--SDVAKNITEKVKNDL-------NANLTVRGFPSEE-------DFEKYIKYENH-S
ARVLAAIIFDYDFKYSNDRLPLKVKYRLRYHSE---------------KNTPWFTELLFP
VN-PSVGPRNPTSA--EGGSPEYYKDGFLLVQHALDKAIIVYHNGKAAEMLFENVT-IFV
GRFPYPAYYKDRFFLSFLSLFPLAVLLIFSLSELTLIRTIVMEKETRLK-----------
----------------------------EYQFMIGLSNGMLWASYFVTFLLMFLIIVCIL
CVILCVKIV-P-----IVILRNSDPSLI----------------------------FVFF
LCFVVATITFGFLITTFFSKT---TLAVSVGGFLFFLSFFPFVVVITMYGMLSHMGKLAS
CLLSNVAVALGINSISNLEMK-EYGAKWNNFLSQVSPDDDLTLAQIMGMLLFDAFLYG--
LLAWYIDAVFPGKYGMPKPWY-FFM------QKGY-WLG-KATSIRKK--EDMPVTSTVQ
NAYFEEEPVGLMAGI-RIQH-LYKEF-TLQNMTVLAVQDLSLNLYE---GQITVLLGP-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSVLTGLYRP-TSGKVYISGYDISKDMVQVRKSLGLCPQDDILFHHLTVSE
HLYFYCVIKGVPPKI-RSKEINKMLLSFDLIEKRDALSKSLSGGMKRKLSIIIALIGDSK
---V-VILDEPTSGMDPVSRRFTWDVLQKHKENRTILLTTHHMDEADVLGDRIAIMAKGT
LQCCGSTIFLKKV-YGVGYHLIIVKDPHCDVKEISK---LIKYHVPEAKLE---NNVAAE
LSFILPKEYTNRFK---D-LFTEMEERQEELGIASFGISITTMEEVFI-------RVSQS
NNPI-L-QT--LKSEDESEDINQ-NMNVPRNF------------------ER--SSF---
--PSNLNEHSNVTFNTGWTLYSQ-QFFAMFMKRAMFSWRNWNLIL-LQILALLGIFYFLM
SDVEFS------RGE-ELEREMDLEQYGETIV---PFSISGNSE-------FTMNFVKNL
EILLKAKKQKLHE-VK-----GDLKAYL-----VGNQKCIYSCIIAFSIEVNGSENIVKF
WFNNEAYHSS-----------------------------PLSLAVLDNVIFMSLSGPDAS
ITVINKPQPARSAFGGP---EYS-----AMTGTQVALNLYFGVSILV---------SG--
FCLLTVNERVTKAKHIQFLSGVYALNFWLSALLWDFLIFFIS-----CCLLL--------
VVFVFSDLKILVTGYRLLD-TLLIFIVFGWSVIPFMYLISFLFSSHTSAY------TKLV
IFNYCAG--------IVGAIADLFITSI----QGKEAASKSILLNAMMVLPIHNFGMSIS
RHYD-------------IQHTKL-ACASQEK-VSPFMD----CSKA-V-TERSIYTLERD
AVGRY--LIAMA---------------VTGLLFLLLIFLLETTL-WKLKTFVFRYILFG-
IFKKCNKD---TVSKE--LSGESEDEDV-----QNERNRILEDPQ---KSLNSVVLIKEL
TKVYFAT--PVVLAVRNISVAIQKQE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFQILTGEEVASSGDVFVE
RLSITKNILKVRS-KIGYCPQFDALLDYMTAREIMIMYARL-WGIPETKINNYVKKSIQA
LNLE-PYADKYIYTY---SGGNKRRLSTAIALM---------GKPSVIFLDEPSTGMDPV
ARRLLWNAVTQTRESGKAIII--TSHSME----ECDALCT-----KLAIMVKGKFMCLGS
PQHLKNKFGNVYILKVKINI-------DENE---NKLKDFKTFIETA----F--------
-P-GSEL-----KYENRGIINYYVPSKNNSWGK--MFGILEEAKEEFNLEDYSISQITLE
QVFLTFAGSQNPEVGYREGHP---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNQLT
VNQLTVLLWKNFTL---KKRQIISTSAELLAALLFVIMLLIFRALTD-MNIA--------
----------------------GPYHFTP--QPIAIMPSFIKDA--------QEWELIYI
PSE--IDVVREIIEDVKRNL-------NTTIKVRGFPSEA-------EFEEYILFDNM-S
QKVLAAIVFDCGFKNKSDPLPLQVKYHLRFVGAQRTIW--------WPDKIGWKTKLLFP
NH-PSIRPRNPNYL--DGGSPGYIKEGFL

PF12698 // ENSGT00760000118965_2_Domain_0 (330, 665)

AVQHALDRSIMLYHESSAGKKLFDEID-TVI
QRFPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIMGLRNWIIWIGYFFTFFPLYVIVILLI
CILLFI----VE----EPVLRYSDCSFI----------------------------FVFL
TCYAIASICFAFMVSTFFSKT---RLAASAGNLLFFASFFPYNFISEYYGMLNLTTKITA
CLSANVALALGINILIKLEIQ-EIGVKWHNLWTPANLEDNLNFGYMLGMLLFDAFLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YVEAVFPGQCGVPQPWY-FFL------MRSY-WFGKPKIRKT-T--E-EAKCTPII
HNCYEAEPPNLEAGI-HIMH-LH-----KEFRNKPA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNLSLNIYE---GQVTVLLGH-N
GAGKTT--TLSVLTGVYPSASRVKAYINGYNISDNMIEVRKDLGFCPQHDLLFDDLTLSE
HLFFYCMIKGIPQNI-NCEEIDRMLSAFNLQENYHTLSGSVSGGVRRKLSIVLALMAGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1181)

SSGMDPVSRRATWDILQHYKHNRTILLTTHYMDEADVLGDRVAIMVRGT
LHCCGSSVFLKQI-YGAGYHIVMEKEQYCDVDNIIA---MIQQHVPGAVLE---NNIENE
LSFILPKKYVSRFE---T-LFTELEMRQKALGIASFGASITTMEEVFVK--VNKLATPQK
SIQTI--QPYYLAYRK-MRQDEQHNVNMPINY------------------SKPN------
--FPYLSEIATVKFNTGVPLYRQ-QFYSLFIKRALFISRN

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKFML-LQIIVVMVVTTYLL
LALHLD-------NNDIPERELNLSHYGRTIV---PYSTSGNSD-------LALKLTKNL
NIFLKSKNQNGRK-IR-----GDMNDYI-----LKNKDCHTFCLVALSIKVERNKTVLTI
FFNNEAYHSP-----------------------------AISLSILDNILFMTLSGPDAS
ITVFNKPQPL--PHYGSNI---V-----PVNGLQIVQCLAFGISVVV---------GS--
FSIQTVTERISQAKHIQFLTGVCVHTYWLSALLCDLIFFFFA-----CCVLL--------
GIFKFCQLEAFVVHYNFLD-TILIFMLYGWCVVPLTYIGSFLFNSSTAAY------IKIT
LFNYFST--------MFSIIIYTIIQFYG---NDFPNFVHILTRAILMALPSYNLAMSIS
KYFD-------------DYEVKR-LCAREF--KSIYVD----CSDP--YTQNNVYGFGEH
GIGKF--LITLA---------------TMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1815)

LLSLESVS-CSLKSFVFRNVIFY-
FYNKLRKGRNATPSNQ--RTKEDEDEDI-----KREKGKVFTLL---LRLQNTPLLLNEV
TKIYFKC--PVVKA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTAEETITSGIAFID
GNSVTRTPRKIRS-RIGYCPQTESVLNHMTGRESLVMYARL-WGVLEQDINEYVEAFLHS
VHLE-PIADQFIHTY---SAGSKRRLSTAIALM---------GKSSVVFLDEPSIGMDPV
AQHLLWETITWICKTGKAIII--TSHRME----ECEALCT-----RLAIMVKGRFTCLGT
PQHVRKRFGHVYTLTVRINI-------AKDE---DKVEEFKNFIKVT----F--------
-P-GNIK-----FQEFHGTIGYYIPSKEIYWGK--VFAILEEAKVLFKLEDYSVKRVTLE
QIFLTFANTDKMRTYQEIKLQ---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLQ
MRQFSVLLWKNFLL---KSRKVVGLVVEIILIFLLFVWTLTVRRISK-KTFI--------
----------------------NDVIFKP--ILLT-LPEFLN------EN--FDYE

PF12698 // ENSGT00760000118965_2_Domain_0 (177, 663)

LAYV
PSE--SDAARNITEMVKKDL-------NFNFKVQGFPSEE-------SFEKYIKYENK-A
AHVLAAIVFDHKFKTSNERLPLQVKYSLRFGRIYNPENVSK--PSEDQKEVEWNTSTLFP
SV-PSLGPRNFFEN--DGGDPGYIREGFLIVQHSVDKAIMMYHSGRAAEVMFANTT-IYA
ERFPHPAFIHDTFLWTFIAMLPWTILFTFTQMALVIVGTIMLEKEKRLK-----------
----------------------------EYQLMVGLSNAMLWVSYFITFLVMYFIIICLL
CGILFLKIT-H-----ERVFQHSDPFFI----------------------------AFYF
TCFAVSSMLLGFLISTLFNKA---SLATSIAGFLHFLTFFPYLIFYHKYDQTGLSGKLAL
CLITNTALAFGTDLICKLEMK-GHGAQWYNFATKVNVDDDLTLAHIIGMFLFSAFLYG--
LV

ENSGT00760000118965_2_Linker_0_1 (663, 758)

AWYLDAVFPGKYGVPKPWN-FFL------QKAY-WFGEPALS--R---EESQVSGLLP
SDFMEPEPVGLVAGI-RIQH-LYKEF-ILKNSTLMAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

NDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSILTGLYLP-TRGKVYISGYDISSDMVQIRKSLGLCPQDDLLFPMLTVSE
HLHFYCVIKGIPLQN-RSRETHRMLTSFGLLQQSNTMSKDLSGGMKRKLSIIIALIGGTK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1186)

SGMDPVSRRATWDLLQHYKKDRTILLTTHHMDEADVLGDRIAILVMGT
LKCCGSSLFLKKL-YGVGYHLVIVKTPDSNDEKIFQ---LIKNYIPTAKME---TNVAAE
LSFILPKEHTDRFA---E-LFTDLEGKEEELGISGFGVSMTTMDEVFFK--VSNLEDLKL
NTEIA--PSASIESQ--SPSEDNQNTNVSRNF------------------ERP-------
--GY-SRRHLDSSFNDGWSLYVQ-QFRAMFIKRVMFSWRYWQLLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1186, 1719)

-LQLLALLGLTYLLI
KGISFS------V-PEKPARVMDLEQYGETIV---PFSVSGDPN-------LTQILTKNL
EIMLKAKKQKIHK-VQ-----GDMKNYL-----LRNKDCIYSCIVAFSIDVTTEEKTFIF
WFNNEAYHAS-----------------------------PLSLSILDNIIYKYLSGPDAT
ITVSNNPQPQRVTKDKS---DET-----SASGIQIVFNLLFGMSIFT---------SG--
FCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIVHFVA-----CVLLL--------
IVFLYTDVDILLEKYHFLD-TMLILMLFGWSIIPFIYLLSFLYNNSTNAY------IKIF
VFNHCLG--------FMSIIVDAVVQII----PDIKTSTKNLILNSMLLLPIYNFGMSIY
KYYN-------------IQEIRK-LCSSLGY-LNTIPS----CKSQ--IIDIPIYSMDQK
AIGRH--VTAMA---------------ATGLTYFILII

ENSGT00760000118965_2_Linker_2_3 (1719, 1816)

LLETTS-WNLMTFIYRYVLFG-
IYRIFYKV---RMFEE--LSGYSEEEDV-----QNERETILNHPQ---HSLNSTVLIKEL
IKIYFKI--PPTLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNVSVAIQKEE-CFGLLGLNGAGKTTTFKILTGEEIATSGDVFIE
GYSITRNILKIRS-KIGYCPQFDALLDYMTSREILTMYARV-WGIPENNIIAYVDNLLKM
LYLK-PQANKFIYTL---SGGNKRRLSTAIAIM---------GNSSVVFLDEPSTGMDPL
ARRMLWNAVIKTRESGKVIII--TSHSME----ECEALCT-----RLAIMVQGKFVCLGS
PQHLKNKFGNIYTMTIKFKI-------DTDD---NMVQDLKNFIAKV----F--------
-P-GSDL-----KQENQGILNYYIPSKNNSWGK--VFGILEKVKEDYNLEDYSISQITLE
QVFLTFANPDNTQSDYEKAVP---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNQLI
VNQLTVLLWKNFTL---KKRQIINTSAEVLAALLFVIMLLIFRAITD-LNIV--------
----------------------GPYHFTP--QPIATMPSFIKDA--------QEWELIYI
PSD--IDVVREIIEDVKRIL-------NTSIKVRGFPSEA-------EFEEYILFDYM-S
QKVLAAIVFDCDFKNKSDPLPLQVKYHLRFVGAQRTIW--------WPDKIGWKTRLLFP
NH-PSIRPRNPNYL--DGGSPGYIKEGFLAVQHALDKSIMLYHESS

PF12698 // ENSGT00760000118965_2_Domain_0 (347, 665)

AGKKLFDEID-TVI
QRFPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIMGLRNWIIWIGYFFTFFPLYVIIILLI
CILLFI----VE----EPILRYSDCSFI----------------------------FVFL
TCYAIASICFAFMVSTFFSKT---RLAASAGNLLFFASFFPYNFISEYYGMLNLTTKITA
CLSANVALALGINILIKLEIQ-EIGVKWHNLWTPANLEDNLNFGYMLGMLLFDAFLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 807)

YVEAVFPGQCGVPQPWY-FFL------MRSY-WFGKPKVRKT-A--E-ETKCPPIV
HNCYEAEPPNLEAGI-HIKH-LH-----K-------------------------------
------------------------AY

PF00005 // ENSGT00760000118965_2_Domain_1 (807, 912)

INGYNISDNMIEIRKDLGFCPQHDLLFDDLTLSE
HLFFYCMVKGIPQNI-NCEEIDHMLSTFNLQENYHTLSGSVSGGVRRKLSIILALMAGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1181)

SSGMDPVSRRATWDILQHYKHNRTILLTTHYMDEADVLGDRVAIMVRGT
LHCCGSSVFLKQI-YGAGYHIVMEKEQYCDVDNIIA---MIQQHVPGAMLE---NDIENE
LSFILPKKYVSRFE---T-LFTELEMRKKALGIASFGASITTMEEVFVK--VNKLATPQK
SIQTI--QPYYLAYRK-MRKDEQQNVNMSINY------------------SKPN------
--FPYLSEIATVKFNTGVPLYRQ-QFYSMFIKRALFITRN

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKFML-LQIIVVLVVTTYLL
LALHLD-------SNDMPERELNLSHYGRTIV---PYSISGTSD-------LALNLTKNL
KILLKSKNQSLRK-IR-----GDMNDYI-----LKSKDCHTFCLVALSIKVERNRTVLTI
FFNNEAYHSP-----------------------------AISLSILDSILFMTLSGPDAS
ITVFNKPQPL--PHYGSNI---V-----PINGLQVVQCLAFGISVVV---------GS--
FSIQTVTERISQAKHIQFLTGVCVHTYWLSALLCDLIFFFFA-----CCVLL--------
GIFKFCQLEAFVVHYNFLD-TILIFMLFGWCVVPLTYLGSFLFNSSTAAY------IKLT
LFNYFST--------MFSIIIYTIIQFYG---SDFPNFVHILIRAILMALPSYNLAMSIS
KYFD-------------DYEVKR-LCAREF--RSIYVD----CSDP--YTQNNVYGFGEH
GIGKF--LITLA---------------TMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1815)

LLSLESVS-CSLKSFVFRKIIFY-
FYNKFRKGRNATVSNQ--RTKEDEDEDI-----KKEKGKVFPLL---LRLQSTPLVLNEV
TKIYFKC--PVVKA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGTAFVD
GNSVTGTPRKIRS-RIGYCPQSESVLNHMTGRESLVMYARL-WGVLEQDINEYVEAFLHS
VHLE-PIADQFIHTY---SAGSKRRLSTAIALM---------GKSSVVFLDEPSTGMDPV
AQHLLWETITWVCKAGKAIII--TSHRME----ECEALCS-----RLAIMVKGGFTCLGT
PQHVRKRFGHVYTLTVRINI-------AKDE---DKVEEFKNFIKVT----F--------
-P-GNIK-----FQEFHGTIGYYIPSKEIYWGK--VFEILEEAKVLFKLEDYSVKRVTLE
QIFLTFANTDKMRTYQEIKLQ---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNWLI
INQLTVLLWKNFTL---KRRQVISSVTEILESLLFVIMLLIFRALTD-INIV--------
----------------------GPYHFTP--QHVATMPSFIKDA--------KEWELIYI
PSD--IDVITEIIENVKKTL-------NTTIKVRGFPSEA-------DFEEYILLDYT-S
QKVLAAIVFDCGFKNKNDPLPLQVKYYLRFVSVQRT--------------IGWKTGFLFP
NH-PSLQTRNPDFL--DGGSPGYIREGFLAVQHALDVSIMLYHESSAGKMLFDEIN-VLI
QRFPYPAHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------VVSLTF--------------------FNYLLV
CIQHFW----IL----EPILRYSDCSFI----------------------------FVFL
ICYAIASICFAFMISTLFNKT---HLAASAGNLLFFASFFPYNFISKHYGMLNLTSKVTA
CLSANVALALGLNILIKLEIQ-EIGVKWHNLWKPANLEDNLIFGYMFGMLLFDAFLYS--
LVTWYIETVFPGQCGVPQPWY-FFL------TRSY-WFGKPKIRKT-E--E-ETTCFSIV
HNCFEAEPTNLVAGI-KIKR-LY-----KEFRNKPA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNLSLNVYE---GQVTVLLGH-N
GAGKST--ILSILTGVYSSPLR--VYINGYNISDNMIEIRKDLGFCPQHDLLFDDLTLSE
HLFFYCRIKGMHQNI-NYKELDRMLSIFNLKDNFHTLSSSMSGGVRRKLSIIIAFSGGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1183)

SSGMDPMSRRATWDILQYYKHNRTILLTTHYMDEADILGDRIAIMVRGT
LHCCGSSVFLKQI-YGAGYRIVMEKEPYCNINNIFA---MIQHHVPSAVLE---NDLGNE
LSFILPKKYVSRFE---A-LFTELEINQKILGVANFGASITTMEEVFLK--VNNLAAPQR
NIQAV--KPYYMIYGK-KRQDKQQNVNMPRNY------------------NRPN------
--FPYLSEITTIKFNTGFPLYCQ-QFCSMFIKRALFIWRNWK

PF12698 // ENSGT00760000118965_2_Domain_2 (1183, 1717)

LML-LQIIIVLVVTTYLL
LALNLD-------DDGIPERELDLRQYGGTIV---PYSISGNSD-------LALNLTKNL
KIFLKSKNQSLQK-IK-----GDINDYI-----LESKECHSFCIIALSIKVEKNKTVLTV
FFNNKAYHSS-----------------------------AISLAVLDNILFMTLSGPNAS
ITVFNKPQPL--PYYGSNT---M-------YGLQIVECLAFGISVVV---------GT--
FSLQTVTERVSQAQHIQLLSGVCVLTYWLSALLCDLMFFFIP-----SCALL--------
GVFRFCQMDAFVVSYNFLD-TMLIFMLYGWCVVPLVYLGSFLFHNSTAAY------IKLT
LFNYFST--------IFSIIIYTIVQLHG---SDLPKCISSFIKTGLMILPSYNFAMSIS
KYFD-------------DYEVKK-LCAKKF--RSLHMN----CSEP--YTQNNVYGFGEH
GIGTF--LITLA---------------AMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LLSLEMVS-WNLKNFVFRNIIFY-
FYNKIRDSRQAAVSNQ--GTK-DEDENI-----RQERRKVLTLSS--LKSQETPLVLNEV
KKIYFKC--PVVKAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGVALID
GSSVIKNLRKIRS-RIGYCPQSESVLNHMTGRELLSMYSRL-WGVPEQNINGYVETFLHS
VQLE-SVADWLIHTY---SGRSKRRLSTAIALM---------GKSSVVFLDEPSTGMDPG
TQHLLWDTVTWIRNTGKAIII--TSHRME----ECETLCS-----RLAIMVKGSFACLGS
PQHVRKRFGLVYTLTVKINI-------AKDR---DKIAEFKRFIQTT----F--------
-P-GNIK-----NQEFQGIIGYYIPSKEICWGK--VFEIMEEAKVRFNLEDYSVKQVTLE
QIFLTLANTDKMILQ---------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI--------

PF12698 // ENSGT00760000118965_2_Domain_2 (1436, 1718)

-SG--
YCLLTVTERTTKTKHIQFVSGVSVIVYWLSALLWDFIVFFAS-----CFLIM--------
GVIKYHKFDIYVMDYHILE-TMLIFMLYGWSAIPFVYLISFVFSGSTSAY------IKLL
LLNYFSG--------TLGFLIG--NILENKQLTSMSNTTRTILGNSLLFFPNYNLAKCIG
EYTS-------------IYEMKI-LCTIYKN-LSVYLN----CSKE--NTEKSIYSLEEF
MIGKY--LIVMS---------------TTGFIFLLLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FLWETTS-WRLRTFLNQHIFFR-
IYKRYRKD---IVAKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLNSTVLIKEL
IKIYFKS--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGYNGAGKTTTFQILTGEESPTSGDVFID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMVMYARI-WGVSEPQIGLYVNKWLNS
LDLE-SHADKLIRTY---SGGNKRRLSTAIALM---------GRSSVIFLDEPSTGMDPV
ARRLLWDAVTKTCESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKFKT-------E------AKLEDFKCYVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSISQITLE
QVFLTFANPEKAS--SDEENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

ASRPSPSPPGEAAS-ATALHALRCPKAAPLFPECCGVYLNSVRPPASA--VLAALVKMAV
PRQLLLLLWKNYTL---QKRKVLVTALELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQVLPLFFTIPP---PG--DAWELAYI
PSH--SEAARTVTEAARKAL-------VINMRVRGFPSEK-------DFEDHVRYDNH-S
ANVLAAVVFQHTFNHSKDPLPLAVKYHLRFSCTRRNYMWTQAGSVFLKEAEGWYTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMHYHANTSAHQLFQKLT-VMA
KRFPYPPFISDPFLIAIQYQLPLLLTLSFTYTSLAIIRAVVQEKERKLK-----------
--------------------------XXXXXXXXXXXXXXXXXXXXXXXX----------
-------XX-XX----XXXXXXXXXXXX----------------------------XX--
---XXXXXX----XXXXXX-----------------------------------------
---------XXXXXXXXXXXX-XXXXXXXXXXXXXSVGGEFNFTQVLLMLLPDSLLYC--
LLT-YVESVLPGKYGTPKPWY-FFL------LPSY-WRGSPRTALGKED-DDSDPEKVLR
TEFFEAEPEDLVAGI-KIKH-LSKVF-RVGGEDKAAVRDLNLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISRDMVQIRKNLGLCPQHDVLFDNLTVTE
HLYFYAQLKGLSRQK-CPEEVKQMLHTLGLEDTRDSRSRFLSGGMRRRLSIGIALIAGSK
---V-LLLDEPTAGMDAISRRAIWDLLQQQKSDHTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNLEGVSQ---LVPHHVPNATLQ---SSAGAE
LSFVLPKESTHXXX---X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VGKLVDSSM
DIQAV--QLPALQYQH-ERRASDWXXXXXXXXXXX--------XXXXX------------
-XXXXXXXXXXXXXXXXLALHCQ-QFWAMLLKKASYSWREWKMVA-AQVLVPLTCVTLAL
LAINYSSEI-----LDDPVLKLTLGEYGRTVV---PFSAPETSR-------RGRQLSELL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFRLLCGPRAS
IVVSNHPQPRSALQAAKDQ-FNE-----GREGFDITLNLLFAMAFLA---------ST--
FAVLAVSERAVRAKHMQFVSGVHAATFWLSALLWDLASFLVP-----SLLLL--------
AVFAYHEEEAFSQRENALA-VTLLLSLYGSAIAPFTYLASFFFDSAGSAC------VKLV
VLLTFLS--------IGPFIL---VSVTSEQXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXX-------------XXXXXX-XXXXXXXXXX-------XXXXXXIKYQENFYAWNAP
GVGRF--VTSMA---------------ASGFIYLALLFLIETNLLWGLRTAVCAF-----
-WRRR---M--LTELCSRSAVLPEDQDV-----AAERSRILAPSLXXX-XX-XXXXXXXX
XXKYEQQ--APLLAVDRLYIAVQG-E-CFG-LGFNGAGKITTFKMLSAEEAITAGDAFVG
GHSVSTDIGK--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDTLW
LNQFAILLWKNFIL---KKRKMGSLIVEISMTVLFCSLILLLRKHSK-REFT--------
----------------------QATLFQS--LPLNKLPAFLTN-----KK--KDYELVYV
PSG--SDAAKNITEKVKDDL-------NANLTVRGFPSEE-------DFEKYIKYENQ-S
VLVLAAIIFDHEFKNSNDRLPLKVKYRLRFHSI---------------KNTPWFTELLFP
VN-PSRGPRNPSST--EGGSPDYYKGGFLLVQHALDKAIIVYHNGRAAEMLFANVN-IFV
SRFPYPTYYKDNFFLSFLSLFPLAVLLIFSLTELTLIRTIVMEKETRLK-----------
----------------------------EYQFMIGLSNGMLWASYFVTFLLMFLIIVCIL
CVVLFVKIV-P-----VVVLQNSDPSLI----------------------------FVFF
LCFVVATITFGFLITTFFDKT---SLAVSIGGFLFFLTFFPFVVVITMYGMLSRTGKLAS
CLLSNIAVALGITTISKLEIK-EYGAKWNNFLSRVSPDDELTLAHIMGMLLFDAFLYG--
LLAWYIDAVFPGKYGVPKPWY-FFM------QNRIKWFFIKNLYLKEC--VVRSLDPSEE
YTIMEQEPVGLIAGI-RIQH-LYKEF-TLQNMTVLAVQDLSLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSILTGLYRP-TSGKVYISGYDISKDMVQVRKSLGLCPQDDILFHHLTVSE
HLYFYCVIKGVPPEI-QSKEINKMLISFGLIEKHDALAKSLSGGMKRKLSIIIALIGGSK
---V-VILDEPTSGMDPVSRRFTWDVLQKHKENRTVLLTTHHMDEADVLGDRIAIMAKGT
LQCCGSTIFLKKV-YGVGYHLIIVKDHHCDVKEISE---LIKYHIPEARLE---NNVAAE
LSFVLPKEYTDRFK---A-LFTEMEDRQEELGIASFGISITTMEEVFIS--ISEIRVSQS
NNQI-L-QT--LKNEDESEDTNQ-NMNVPRNF------------------ER--SYA---
--SSNLNERSNITLNTGWALYSQ-QFFAMFMKRAMFSWRNWNLIL-LQILALLGIFYFLM
SDVELS------IGEEDLDREMDLEQYGQTIV---PFSISGNSE-------FTTNFVKNL
EILLKAKKQKLHE-VK-----GDLKTYL-----VDSQKCIYSCIIAFSIEVNGNENTVNF
WFNDEAYHSS-----------------------------PLSLAVLDNVIFMSLSGPDAS
ITVVNKPQPVRSASSGP---KYS-----MMTGTQIALNLYFGVSILV---------SG--
FCLLTVNERVTKAKHIQFLSGVYALNFWLSALLWDFLIFFIS-----CCLLL--------
VVFTFSDLKILVTGYRLLD-TLFIFMVFGWAVIPFMYLISFLFSSHTSAY------AKLV
IFNYCAG--------IFGAVADVTISSI----QGEEAASKSLLLNAMMVLPIHNFGMSIS
RHYD-------------IQHTKF-ACTSKEK-VSSVMN----CSKA-V-TERSIYTLEYD
AVGRY--LLAMA---------------VTGLLFLLLIFLLETTL-WKVKTFVFRYILFG-
IFKKSNKD---RVSKE--LSGESEDEDV-----QNERNRILDNPQ---ESLNSIVLIKEL
IKVYFSK--PVVLAVRNISVAIQKQE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFEILTGEEVASSGDVFVE
RLSITKNILKVRS-KIGYCPQFDALLDYMTAREIMIMYARL-WGIPETKINNYVKKSMEA
LNLE-SYADKYIYTY---SGGNKRRLSTAIALM---------GKPSVIFLDEPSTGMDPV
ARRLLWNAVTRTRESGKAIII--TSHSME----ECDALCT-----KLAIMVKGKFVCLGS
PQHLKNKFGNVYILKVKINI-------DENK---DKLEHFKTFVETA----F--------
-P-GSEL-----KDENRGIINYYVPSKNNSWGK--MFGILEKAKEEFNLEDYSISQITLE
QVFLTFAGSQNPEVGYREGHP---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASQE
SRKLLLLLWKNFTL---KRRKFGALVSEIVLVLLLSTVLLTTRHLLS-IKKI--------
----------------------EALYFPD--QPVSTVPSFFRASV--TSF--YPWELAYV
PSN--IMVVENIVKNVKTDL-------NLHMKVIGFPSES-------GFEEYARSTVN-S
RNILAAIAFGHSFANSSDPLPK

PF12698 // ENSGT00760000118965_2_Domain_0 (263, 665)

KVKYYLRFSDIKKNIN-S----GAYYQGDTWLTKFLFH
SL-HLVGPRNPYEA--DGGSPGYITEGFLAVQHAVDKAIMLHHGGAAAAALFNDVS-LFI
QRFPYPAYYHDYFYLFAATFIPLTVACTFFFNHFVLVWSIVWEKENRLK-----------
----------------------------EYQLMIGLRNWMFWVAYFFTFLCLYFINIIFM
CMVLFVKIE-P-----APIFQYNDPTLV----------------------------FIFL
LFYAISSIFFSFMVSTLFNKV---SLAMSLGSFLFFLTYFPAVAMHQSFERMPCKQKLIW
SFDFNVGMAFGFRFLVNADTK-KTGMKWSNIFLSTDS-DSFLFAYVLGMLLVDAFIYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGEYGVPKPWN-FFL------MHSY-WFGEPPQQ--KP--EITQFYERVE
SKYFEAEPIDLTAGI-QIKH-LHKVF-QKNNTTKVAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQVTVLLGH-N
GAGKST--TLSILSGLYPP-TSGEAYVHGEDISQHMDQIRNSLGFCPQQNLLFDHLTVSE
HLYFYCRIKGVPQKM-YLEETNNMLSAFNLMEKCDAFSKSLSGGMKRKLAIIIALIGGSK
---V-AILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1269)

SGMDPASRRSTWDILQTYKQNRTILLTTHYMDEADVLGDRIAIMVRGT
LRCCGSSVFLKRL-YGVGSHLVMVKEPYCDIAEISK---LIHPYVPTATLE---TNVGNE
LSFILPKEYTHRFE---A-LLTALEENQENLGISSFGVSITTMEEVFLK--VSNLEDSKT
DIEAT--QSPS--VGS-KE---DKNRDVES-S------------------WRVG------
--FPTQSEDQNIVFNTGCSLYLQ-QFRAMFMKRLMYNWRNWRGIL-VQILGLVISTFLLL
KSHEFR-------YK--KIRQMNLDEYGQTIV---PFSILGKSN-------LTTSLLTHL
ENMLKPGN

PF12698 // ENSGT00760000118965_2_Domain_2 (1269, 1718)

HQLKE-VQ-----GDLLKYL-----EGNDECIHLCIIALSIKVVTNRVNLTV
LFNNEAYHSP-----------------------------SLSLAVLDNILFMSLSGPDAS
ITVFNKPQPKPQRKEW----PG------STDGKIVAFKIQLGMALLV---------SG--
FCILTVTERHTKTKHMQLLSGVSIPVYWLSALVFDLIIFFIS-----CCFLL--------
VMFKHCKFDIYVTDYHILD-TMLILTLFGWSAIPLTYLMSFLFSKSNSAY------INLL
VFCYLSG--------TLSLLMDT--IIEARISTIMSNSTQTFLLNTLLLFPMYNLGKCIS
EYTV-------------IYRKKM-LCIQQKN-ALKYLN----CSNK--YTKKNIYSLKKP
MLGKY--LIAMS---------------IAGFVFLLLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENIS-WKVKMLIHQHVYFG-
ACKKYKPD---IISKE--LSGTSEDNDV-----ENERREILYQPE---KFLNCPVLIKEL
TKIYFKS--PLILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQERE-CFGLLGFNGAGKTTTFQILTGENIPTAGDVFID
GISITKNIVKVRS-KIGYCPQFDALLEYMTGWEIMIMYARI-WGISEHQIQPYVKKHLNS
LDLE-SHANSLISTY---SEGNKRRLSTAIATM---------GKPSVIFLDEPSTGMDPR
ARRLLWDTVIKIRESGKAIII--TSHSME----ECEALCT-----RLSIMAHGKLTCLGS
PQYLKNKFGNIYILKTKVKS-------G------ETLDEFKNFITLT----F--------
-P-GIEL-----QQENQGILNYCIPRKNNSWGK--VFGILEKAKEQYNLEDYSISQITLD
QVFLSFADQDRK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDFLE
INKFMILIWKNLIL---KRRQFILLVLEISLMFLFATLLLVTRYLVA-IHQY--------
----------------------GPFRYSA--QPLDELPSFVTAPV--SFP--GNWEIAYV
PSK--SAAVKTIIENMINDI-------NINIKVQGFSSEK-------DFEDYVMYKNN-S
KKMLFAVVFDHNFKNSFDPLPLKVNYYLRFSSFQRSKMLV----SNYFPAQSWETALLFP
SN-PTVGPRNLYDE--DGGSPGYIREGFLFIQHSVDKAIMLYHNSIAAEELFENIR-VFA
QRFPYPVYNSDFFFAYSGIFIPLVILFMFSMNHFALIQCIVWEKENRLK-----------
----------------------------EYQLMIGLSNWILWAAYFVTFFFLYLIVTILM
CISFFAKIE-P-----VPVLQYSEPSLI----------------------------FVFL
MCFAIASIFFSFMTSTFFNKA---HYAVSVGGFLYLVSYFPYSIVSQRYEDFTLTQKVAF
CLCSNVAMAMGTKLLVNAEIQ-GTGIKWSNIFTSANM-DDFVFGYVLGMLLFDAFLYG--
LVAWYIEAVFPGEYGMPKPWN-FFL------LRSY-WFGEPTEK--KQ--ERSQFYEAIQ
NKYFEAEPTGLVAGI-QIKH-LCKVF-RVHNTTKIAVKDLSLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

ST--TLSILSGLYPP-TSGQVYINGYDTTTDMTKIRKILGLCPQQNLLFNYLTVSE
HLHFYCVLKGIPPKM-HPVEIDHMLTTFNLLEKRDEFSYSLSGGMKRKLSIIIALIGDSK
---V-VILDEPTSGMDPVSRRATWDVLQQYKQDRTILLTTHYMDEADILGDRIAIMDQGT
LQCCGSSIFLKQI-YGMGYHIVMVKEPHCNVEEISE---LIHYHIPTATLE---NHIGTE
LSFILPKDCTQRFE---A-LFSDLEKRQKELGIASFGASITTMEEVFLM--VNKRAESQR
---VI--H--SPSQMS-KDMNMSNNQNISRNF------------------ETAD------
--SCAQNERSSIIYNTGCLLYHQ-QFYAMFIKRVMFNWRHWKLIL-LQILGLLGVLTFLL
KAGHLS------KEHDEPARKMNLHQYGQTIV---PFSISKNSK-------LSQAFSKHL
DSVLTSENQILKK-VQ-----GNILNYL-----LENKDCVRSCIVALSIEAKIDEIIFTI
LFNNEAYHSP-----------------------------SISLAVLDNVLFMLLSGPNAS
ITVFNKPQPRIVDDDL----NDE-----LTNGLQIAINLHFGMALLI---------SG--
FCLLTVNERVTKAKHIQFVSGVYVLIYWLSALLWDFLIFFIS-----CCLVL--------
GTIKFASAPLWLTNTHVIQ-TITIMEKIGWSLSSIIISLLFVLERKHKAY------MALL
MSSIYSS--------IFSFEYF-FILKDGKKGHRLSNATRTFILNLLTLLPNYNLAKCFN
EYTN-------------IYQNKI-LCISQKQ-PPTYLN----CSKE--NIKKNVFTLEEN
MIGKY--LMLMG---------------ITGFIFLLMIFLRETLL-WRLSTFFNQYIYFA-
IYKKFRKN---IVSKE--LSGESEDEDV-----EKERKRILEQPH---EFLNTTVLVKEL
TKIYFRC--PAILAVKNISFAIQKEE-CFGLLGFNGAGKT

PF00005 // ENSGT00760000118965_2_Domain_3 (1841, 1974)

STFQMLTGEKIITSGDVFID
GFSIIKNIYKVRS-RIGYCPQTDALLEYMTGREIMIMYARL-WGVSEPQIHLYVNSWLNS
LQLE-PHADKFIYTY---SGGNKRRLSTAIALM---------GKPSVIILDEPSTGMDPV
ARRLLWNIVTQTRVTGKAIIL--TSHSIE----ECEALCT-----RLAIMVKGKFMCLGS
PQHLKNKYGHFYIMKAKIKT-------D-DD---EHLEDFKNFITTT----F--------
-P-GSVI-----NHENQKIVNYYIPSKDNSWGK--VFGILEKAKEQFHLEDYSISQITLE
QVFLMFANPDKI------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------LSFPFGGRMAV
FKQFTLLLWKNYTL---KKRKIVVTVLEILLPLLFSGILIWLRQNIHSENIP--------
----------------------NATIYPG--QPIKDLPLFFSFPP---RE--DTWELVYV
PSN--SEAVKTITEMVKKTF-------AINLKVRGLPSEK-------DFEDYIKFDNH-S
YSVLAGIVFEHSFSHYKEPLPLEVKYHLRFSYFRKNNMWEGMNLFFPKDIEGWHTTSLFP
LF-PNPGPREPSFP--DGGEPGYIQEGFLAVQHAVDKAIMQYHASAAATRLFEKVN-IIV
KRFPYPPFISDSFLVAIQYQLPLLLMLSFTYSTLTITRAIVQEKERKL------------
---------------------------KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXLE-EN----IAVITNSDPSLV----------------------------FVFL
MCFAISSISFSFMVSTFFN-----------------------------------------
--------------------K-GIGIQWKYLMKSVNVDDNFTFGHVLIMLLFDSAFYG--
LVTWYVEAVFPGEYGMPQPWY-FFL------MPSY-WCGNQRSMMGKEE-EEDDPEKVLK
TEYIEAEPEDLVAGI-KIKH-LSKMF-MVRNKRKEAIRDLTLNMYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSILTGLFPP-TSGRAYINGYEISRDIVQIRKSLGLCPQHDVLFDYMTVAE
HLYFYAQMKGLSEQK-CPEEVNHILNILDLENKRHSLSKSLSGGMKRKVSVGIALIGGSK
---V-VMLDEPTSGMDPVSRRATWDLLQQQKNDRTIVLTTHFMDEADLLGDRIAIMAKGD
LQCCGSSLFLKHK-YGAGYHMIIVKELHCNTSDISR---LVYHHIPNAILE---SNVGAE
LSFILPKESAHRXX---X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAMDS---------------NLSGIM-DLTDSIGAL-
----IKEDCTTIKFNTRFYLHCQ-QFYAMFTKKALYSWRNWKLLV-AQILVPLTCITLAL
MSINYSSEI-----RDDPILQLTLDQYGQTVV---PFSIYGTSK-------LDQQLSERF
KDMLQAEKQVPRE-VL-----GDLEEFLIFRASVEGEGFNERCLVAASFKDGEDQIAITA
LFNNQAYHSP-----------------------------ATALAIVDNILFKLLSGPSAS
ITVSNYPQPRGAGQATAEQ-AIE-----GSRGHEIAFSLFFGMAALA---------SS--
FCLLTVTERIIKAKHLQFVSGVRIVNFWLSAFLWDLLNFIIP-----CLLLL--------
VVFRAFDVEAFTQDNHLAD-ALMILMLYGWSIIPLMYLMSFLFSGAAAAY------TRLS
IFNILSG--------LATFLI---ISILRMPGLKLLQLS-KTLDMVFLALPSHSLGMSIS
NFFE-------------NYEAKR-FCMSSETAAQ-------NCKKFNIKYQENFFAWKAP
GIGKY--MTSMA---------------ASGFVFLILLFLIETDLLWRLRTLVSNI-----
-FRTQ---N--WAQMHIQSSAIPKDQDV-----EDEKKKVLESLPEL--LLNTPLVIKEL
TKVYSQR--VPFLAVDRISLSVQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 1900)

GE-CFGLLGFNGAGKTTTFKMLTGEDTITFGDAFVD
GYSIITDIKKVRQ-RIGYCPQFDALLEHMTGRETLIMYARL-RGIPERHISNCVKNVLQG
LLLE-PHADKLVKTY---XXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--XXXXME----ECDALCT-----RLTMMVNGQFKCLGS
PQHLKSKFGSGYTLLAKVKS--------GQK---EALELFKMFVNQT----F--------
-P-GSIL-----KDEHQGMVHYHLPSKDLSWAK--VFGILEKAKEKYGLDDYSVSQVSLE
QVFMCFAHLQSSAEDER-------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNQLL
LNQLTVLLWKNFTL---KKRQVLSTVMEVLAALLFVIMLLIFRALTD-MNIA--------
----------------------GPYHFTP--QPIATMPSFIKDA--------QEWELIYI
PSE--IDVVTEIIEDVKRNL-------NITIKVRGFPSEV-------EFEEYILFDYT-S
QKVLAAIVFDCDFKNKTDPLPLQVKYHLRFVGAQRTIW--------WPDKIGWKTRLLFP
NH-PSLKPRNPNYL--DGGSPGYIKEGFLAVQHAVDKSIMLYHESRAGKELFENID-TLV
QR

PF12698 // ENSGT00760000118965_2_Domain_0 (363, 665)

FPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIMGLRNWIIWMGYFFTFFPLYVAIIFLI
CILLFI----VE----EPILRYSDCSFI----------------------------FVFL
TCYAIASICFAFMVSTFFSKT---RLAASAGNLLFFASFFPYNFISEYYGMLDLTTKITA
CLSANVALALGINILIKLEIQ-EIGVKWDNLWTPANLEDNLNFGYMLGMLLLDAFLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQCGVPQPWY-FFI------MRSY-WFGKPKIRKI-G--E-EAKSIPVV
HNCYEAEPSNLEAGI-QIKH-LH-----KEFKTKPAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 912)

NNLSLNIYE---GQVTVLLGH-N
GAGKTT--TLSVLTGVYLSASRVKAYINGYNISDNMAEIRKDLGFCPQHDLLFDDLTLSE
HLFFYCMIKGHPQNI-NCVEINRMLSVFNLQENYHTLSGSVSGGVRRKLSIILALMGGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1181)

SSGMDPMSRRATWDILQHYKQNRTILLTTHYMDEADVLGDRIAIMVRGT
LHCCGSSVFLKQI-YGAGYHIVLEKEPYCDVDNIIA---MIQQHVPGSMLE---NDIGNE
LSFILPKKYVSRFE---T-LFTELEMRQKALGIANFGASITTMEEVFLK--VNKLAAPQR
SIQTI--QPYYLTYKK-MRQDEQQNVNILRNY------------------NKPI------
--FPYLREIATVKFNTGVPLYRQ-QFYSMFIKRALFIGRN

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKLMF-LQIIVVLVVTTYLL
LSLHLD-------DNDIPERELNLSHYGKTIV---PYSISGNSD-------LALNLIKNL
KIFLKSKNQSLKK-IK-----GDMNNYI-----LENKDCRTFCIIALSIKVERNKTVLTI
FFNNEAYHSP-----------------------------AISLSILDNILFMTLSGRDAS
ITAFNKPQPL--PHYGSNT---V-----PVNGLQIVQCLAFGISVVV---------GS--
FSIQTVTERISQAKHIQFLTGVCVLTYWLSALLCDLIFFFFA-----CCVLL--------
GIFRFCQLEAFVVHYNFLD-TILIFMLYGWCVVPLTYLGSFLFNSSTAAY------IKIT
LFNYFST--------MFSIIIYTIVQFYG---EDFPALIHILIKTILMALPSYNLAMSIS
KYFD-------------DYEVKR-LCAREF--RSIYMD----CSEP--FIQNNVYGFGEH
GIGKF--LITLA---------------TMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1815)

LLSLESVS-SSLKNFVFRNVLFY-
FYNKIRKGRHIIPTAK--STKEDEDEDI-----RKEKRKVFTLL---LRLQNTPLVLNEV
TKIYFKC--PVVKA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLVVRKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGIAFID
GNSVTKNPRKIRS-RIGYCPQSESVLNHMTGRESLIMYARL-WGVPEQDINEYVEAFLHS
VHLE-PIADQIIYTY---SAGSKRRLSTAIALM---------GKSSVVFLDEPSTGMDPV
AQHLLWDTVTWVCKTGKAIII--TSHRME----ECEALCS-----RLAIMVKGKFTCLGT
PQHVRKRFGQVYTLTVKINI-------AKDE---EKVKEFKDFIKST----F--------
-P-GNIK-----FQEFHGLLAYYIQQHRNRWGK--VFEILEEA-----------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFRSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHANAATRQLFQRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLITTSFM
TLLFCVKVK-PD----VAVLSRSDPSLV----------------------------LAFL
LCFAISTISFSFMVSTFFS-----------------------------------------
--------------------K-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTWYMEAVFPGQFGVPQPWY-FFI------MPSY-WCGKPRAVARKEE-EDSDPEKALR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAVRDLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHVIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPTSGMDTISRRAIWDLLQRQKSDHTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEDISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEERTAVKLNTGLALHCQ-QFWAMFLKKAAYSWREWKMVA-AQVLVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL--------------------------------------------
-------HSP-----------------------------ATALAVVDNL--KLLCGPHS-
IVVSNFPQPRSA--QAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAAQAKHVQFVSGVHVASFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVHAFTRDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDRVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKRYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILLFLIETNLLQRLRGILCAL-----
-QRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQQ--VPLLAVDRISLAVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYGVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDFLW
FYKFMALLWKNFIL---KRRQLVALIVEIILTLLFASTLLLTRKSLI-IKKS--------
----------------------GPFNYSL--QPVDELPALLEMAI--TFP--GQWELAFV
PSK--SVVVKNIIELVKRDL-------RYNFSVQGFSSER-------DFEKYVKQENN-S
KKVLVAIIFDHEFQNSNDPLPLKVKYFLRFSSFQRNK--Y----VTFFRTDGWETGVLFP
PF-PSAGPRSQSNS--NGGQPGYITEGFLAMQHAVDQAIMKYYNHTATQKLFQDVT-VFV
QRFPYPEYSHDYFFTFFGIVIPLVILFIFSMNHLTLIQSIVWEKEKRLK-----------
----------------------------EYLLMIGLSNWMLWAAYFFTFLSLYSVIILLM
CIIFFAKLE-P-----VPVIQYSDPSLV----------------------------FVFL
LCFAIATIFFSFMVSTFFNKA---HFAVSVGGFIYFATYFPFATVSTNFAQMTFTQKLAS
CLSSNIAMALGTKFLLKAEME-KIGIKWSNIFSSPKM-ENFDFTHVLGMFLFDAFLYG--
LVAWYIEAVFPGEYGVPKPWN-FFL------LRSH-WFGETPEE--KK--ETRQFYETNE
SKYFEAEPTDLVAGI-QIKH-LCKEF-RVQNTTKIAIKDLSLNLYV---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

ST--TLSILSGLYPA-TSGEVYINGYDISQQMVQIRKSLGLCPQQNLLFNYLTVSE
HLYFYCVVKGIPRKT-RLLEIDHMLAAFNLLDKRNEFSCSLSGGMKRRLSMIIALLGGSK
---V-VILDEPTSGMDPASRRATWDVLQQYKQDRTILLTTHYMDEADFLGDRIAIMVEGS
LRCCGSSVFLKKI-YGVGYHIVMVKEAHCNVEEISK---LLQYYIPTATLE---KNVNKE
VSFILPKEYTHSFE---A-LFTDLEKRQYDLGIASFGASITTMEEVFFR--VSNLEDSQT
GIQAT--QTPPPSVMS-EVSVKNQNWSM-----------------------PSN------
--FSTMNEIPAIMFNTGYSLCHQ-QFRALFIKRAMFSWRNWKLIL-LQILALLGSFTFLS
KADKFL------HNNDEKPRQMDLDQYGRTIV---PFSVSGNSN-------LTLIFLKHL
GSMLESHKHTLKE-VQ-----GDLLKYL-----MENEDCIHLCIVAFSIEVKTNKIILTG
LFNNQAYHSP-----------------------------SLTLAILDNILLMTIAGSNAS
ITVFNKPQPHFKDKKQ----SGT-----LSDGVQVALYIHFGMALLI---------SG--
FSLLTVTERVTKAKHIQLLSGVSVPVYWLSALLWDFIIFFIT-----CCLLL--------
GAFKFCQLDIYITDYRFLD-TMLIFMLYGWSAIPLTYLLSFLFTRSTSAY------IKLV
LFNYLSG--------IFSLLIDVTLQFEV-Q-HKMSKTTRAFILNSLLLFPNYNLAKCIS
DYFT-------------FHLIKK-WCSG-NK-PPIYLN----CSKERTAKN--IYSLEEK
MIGKY--MIIMS---------------ITGCICLLFIFFLDTTL-WKIRTFFNQYIYFG-
IYKTFRKG---KVSKE--LFGESDDEDI-----QNERQRILGQPQ---GLLDSPVIIKEL
TKIYFKY--PVILAVKNISVTIQRGE-CFALLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKILTGEETVTSGDVFIE
HFSITKSLPKVKS-RVGYCPQYDALLEYMTGREIMIMCARL-WGVSEPQIQLYVNRWLSL
MQLE-AHADKLIRTY---SGGTKRRLSTAIALM---------GKTSVILLDEPSTGMDPV
ARHLLWNAVTWTYESGKAIII--TSHRLE----ECDAFCT-----RLAIMVQGKFLCLGS
PQHLKNKFGNIYILKVKVKI-------DAQK---GKLDGLKYFITLT----F--------
-P-DSVL-----KQENQGILTYYIPSKDKSWGK--VFGILEDAKEQFNLEDYSISQITLE
QIFLAFASPENTEEGKKKKK----------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LKKLKLLLWKNITL---KKRKTLVTIIELLMPLLFSAIVLYLRFNSV-PRKR--------
----------------------PSTNYSA--VDINLLPEFFHNFP---LK--NKFQLVYI
PSK--SETLKAVIEMAGQSF-------DVEFEVLGYSSVT-------LFENYIINDPK-A
FYILAGIVFNHTFSDNNEPLPLAVKYHLRFSSIQRNYLFRS--LFFDDNLQGWCTSFLYP
PN-PRQGPREFAYA--DGGSPGYHQEGFLAIQHAVDKAIMWHHAHNVTTNMFKSLN-VLV
KRFPFGPYVEDRFFLVLQNEFSLLLMLSFICIELNIINSIGLEKEKRLK-----------
----------------------------EYMCMMGLESWLHWVAWFIIFFICVFIAVSFM
TIIFCMKVE-N-----VAVFTNSDPSLI----------------------------FVFL
MCFAIATIFFAFMVSTFFQRA---HAGTALGGIIFFFTYLPYLYLSFSYTQRSFFQKIIS
CLFSNVAMAMGVRLISMFEAEVGTGIQWRNMG---NVSGEFNFTQVLLMLLLDSFLYG--
LVAWYVESIFPGKYGTPKPWY-FFA------LPSY-WHGKPIPATRSL-LNMRDPVKALK
SEFIQKEPTDLIKGI-EIQD-LYKVF-HRGRTKHIAVKGLTMNLYR---GQITVLLGH-N
GAGKTS--TC

PF00005 // ENSGT00760000118965_2_Domain_1 (791, 913)

FMLIGLIPP-TSGQAYVNGYEISQDMFHIRKSLGWCPQHDILFENFTVAE
HLSFYAQLKGLSHQK-CSEEVKKMLHILDLEDKWASRSRFLSGGMKRKLSIGIALIAGSK
---V-LILDEPTSGMDAISRRAIWDLLQQQKSDRTILLTTHFMEEADLLGDRIAIMANGE
LQCCGSSLFLKQK-YDLGWRVQTRPRPNCNKKNTQT---KYHHKFKNKGLK---RSTNNT
PAFLDTLDSTHWFE---S-LFMDLELRQTELGIASFGVSVTTMEDVFIR--VCILADAST
TIPNI--KRPSLHHWY-ANQTKHWGIN--SVEIIR-------KD--HSKGPG--------
--YSFDQEEILSSKNFNLKLFCQ-QFYAMFLKKVTHSWRNWMLILSIQILLPIVIVILSL
MFFNFKTRS---M--RNVPLELTLKTYGQTVV---PFFISQNSR-------LDPRLSESF
ASMLMAEGQIPLK-VL-----GSMDEFLLKKAKEEPEGFNRLYIVAASFEDVGNHTVVTA
LFNNQVYHSP-----------------------------ALALALVDNFLFKLLSGARAS
ISVSNHPQPQSASEVSENI-LYQ-----GPKGHYLVINLLFGIAFLS---------SS--
FSILIVRERCLSAKHIQLVSGVYVATYWLSALLWDLISFLIS-----SLLLV--------
MVFSYYNEEAFTRNGNMLA-VILMLMLYGSAIIPCIYLVSFSFENAANAC------VKLV
IMLTFLS--------ICPF--VL-ISITGEQELGYTTVA-KSLDDTFLILPGYCLGMAFS
NLYY-------------NFELQQ-LCKTKNLNHIECNE------KEGYVVQKNIYAWESL
GIGKY--LTALA---------------ILGPIYIILLFFIETNMFWKLKTR-FAY-FCT-
--KKN---LA--V-LRKVTL-VPEDQDV-----KEEAKTIQTHLRKLY--EKNPLVVKKI
SKIY-VK-KVPLLAVNEVSFTVQAQE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

SSVFKMLTGEKPITSGDAFVR
GISIKSNIGKVRQ-WIGYCPQFGGLLNFMTGREMLIMYARI-RGIPERHISACVDQILED
LVMD-IYADKLIKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWNAVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
TQHLKSKFGSGYSLRAKVQS-------EGQQ---EALKEFKAFVNLT----F--------
-P-GSVL-----EDEHQGMVQYHLPGRDLSWAK--VFGILEQAKNKYRLDDYSVSQVSLE
DIFLSFACPVPIDQGE--------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNQLT
VNQLTVLLWKNFTL---KKRQIISTSAELLAALLFVIMLLIFRALTD-MNIA--------
----------------------GPYHFTA--QPIAIMPSFIKDA--------QEWELVYI
PSE--IDVVREIIEDVKRNL-------NTTIKVRGFPSEA-------EFEEYILFDNM-S
QKVLAAIVFDCGFKNKSDPLPLQVKYHLRFVGAQRTIW--------WPDKLGWKTRLLFP
NH-PSIRPRNPNYL--DGGSPGYIKEGFLA

PF12698 // ENSGT00760000118965_2_Domain_0 (331, 665)

VQHALDKSIMLYHESSAGKKLFDEID-TVI
QRFPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIMGLRNWIIWIGYFFTFFPLYVIIILLI
CILLFI----VE----EPILRYSDCSFI----------------------------FVFL
TCYAIASICFAFMVSTFFSKT---RLAASAGNLLFFASFFPYNFISEYYGMLNLTTKITA
CLSANVALALGINILIKLEIQ-EIGVKWHNLWTPANLEDNLNFGYMLGMLLFDAFLYS--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 757)

YVEAVFPGQCGVPQPWY-FFL------MRSY-WFGKPKIRKT-T--E-EAKCTPIV
HNCYEAEPPNLEAGI-HIMH-LH-----KEFKNKPA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNLSLNIYE---GQVTVLLGH-N
GAGKTT--TLSVLTGVYPYASRVKAYINGYNISDNMIEVRKDLGFCPQHDLLFDDLTLSE
HLFFYCMVKGIPQNI-NCEEIDRMLSAFNLQENYHTLSGSASGGVRRKLSIVLALMAGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1181)

SSGMDPVSRRATWDILQHYKHNRTILLTTHYMDEADVLGDRVAIMVRGT
LHCCGSSVFLKQI-YGAGYHIVMEKQQYCDVDNIIA---MIQQHVPGAVLE---NNIENE
LSFILPKKYVSRFE---T-LFTELEMRQKALGIASFGASITTMEEVFVK--VNKLATPQK
SIQTI--QPYYLAYRK-MRQDEQQNVNMPINY------------------SKPN------
--FPYLSEIATVKFNTGVPLYRQ-QFYSLFIKRALFISRN

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKFML-LQIIVVMVVTTYLL
LALHLN-------NNDIPERELNLSHYGRTIV---PYSTSGNSD-------LALNLTKNL
NIFLKSKNQNLRK-IR-----GDMNDYI-----LKNKDCHTFCLVALSIKVERNKTVLTI
FFNNEAYHSP-----------------------------AISLSILDNILFMTLSGPDAS
ITVFNKPQPL--PHYGSNI---V-----PVNGLQIVQCLAFGISVVV---------GS--
FSIQTVTERTSQAKHIQFLTGVCVHTYWLSALLCDLIFFFFA-----CCVLL--------
AIFKFCQLEAFVVHYNFLD-TILIFMLYGWCVVPLTYIASFLFNSSTAAY------IKIT
LFNYFST--------MFSIIIYTIIQFYG---NDFPNFVHILIRAILMALPSYNLAMSIS
KYFD-------------DYEVKR-LCAREF--KSIYLD----CSDP--YTQNNVYGFGEH
GIGKF--LITLA---------------TIGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1815)

LLSLESVS-CSLKSFVFRNIIFY-
FYNKLRKGRNAIPSNQ--RTKEDEDEDI-----KKEKGKVFTLL---LRLQNTPLLLNEV
TKIYFKC--PVVKA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGIAFID
GNSVTRTPRKIRS-RIGYCPQTESVLNHMTGRESLVMYARL-WGVLEQDINEYVEAFLHS
VHLE-PIADQFIHTY---SAGSKRRLSTAIALM---------GKSSVVFLDEPSIGMDPV
AQHLLWETITWICKTGKAIII--TSHRME----ECEALCT-----RLAIMVKGRFTCLGT
PQHVRKRFGHVYTLTVRINI-------AKDE---DKVEEFKNFIKVT----F--------
-P-GNIK-----FQEFHGTIGYYIPSKEIYWGK--VFAILEEAKVLFKLEDYSVKRVTLE
QIFLTFANTDKMRTYQEIKLQ---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLQ
MKQFSVLLWKNFLL---KSRNVVGLVVEIILIFLLFVWTLTVRRISK-KTSI--------
----------------------SDVIFNP--ILLT-LPKFLN------EN-

PF12698 // ENSGT00760000118965_2_Domain_0 (172, 663)

-FDYELAYV
PSE--SNAARNITEMVKKDL-------NFNFKVQGFPSEE-------SFERYIKYENK-D
AHVLAAIVFDHKFKTSNERLPLQVKYSLRFGRIYDPENLFQ--PSKYQKEIEWNTSTLFP
SV-PSLGPRNFLEN--DGGNPGYIREGFLIVQHSVDKAIMMYHSGRAAEDIFANTT-IYA
ERFPHPAFIHDSFLWTFIAMFPWTILFTFTQMALVIVGTIMLEKEKRLK-----------
----------------------------EYQLMVGLSNAMLWVSYFITFLLMYFIIICLL
CGILFLKIT-H-----ERVFQHSDPLFI----------------------------AFYF
MCFAVSSVLLGFLISTLFNKA---SLATSIAGFLHFLTFFPYLILYHKYDQISLSGKLAL
CLITNTALAFGTDLICKLEMK-GHGAQWNNFATKVNADDDLTLAHIIGMFLFSAFLYG--
LV

ENSGT00760000118965_2_Linker_0_1 (663, 758)

AWYLDAVFPGTYGVPKPWN-FFL------QKAY-WFGEPALS--R---EESQVSDLLS
SDFMEPEPVGLVAGI-RIQH-LYKEF-ILKNSTLMAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

NDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSILTGLYLP-TRGKVYISGYDISSDMVQIRKSLGLCPQDDLLFPMLTVSE
HLHFYCVIKGIPLQN-QSRETNRMLTSFGLLQQSNTMSKDLSGGMKRKLSIIIALIGDTK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1186)

SGMDPVSRRATWDLLQHYKKDRTILLTTHHMDEADVLGDRIAILVMGI
LKCCGSSLFLKKL-YGVGYHLVIVKTPDSNDEKIFQ---LIKNYIPTAKME---TNVAAE
LSFILPKEHTHRFA---E-LFTDLEEKQEELGISGFGVSMTTMDEVFFK--VSNLEDLKL
NTEIA--PSASIVSQ--SSNEDNQNMNVPRNF------------------ERP-------
--GY-SRRHLDSSFNAGWSLYIQ-QFRAMFIKRVMFSWRYWKLLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1186, 1719)

-LQLLALLGLMYLLI
KGISFS------V-PKEPARVMDLEQYGETIV---PFSVSGDPN-------LTQILTKNL
ETMLKAKKQKIHE-VQ-----GDMKNYL-----LTSKDCIYSCIVAFSLDVTTEEKTFIF
WFNNEAYHAA-----------------------------PLSLSILDNIIYKYLSGPDAT
ITVSNNPQPQRVTKDKS---NER-----SISGIQIVFNLLFGMSIFT---------SG--
FCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIIHFVA-----CVLLL--------
VVFLYTDVDILLEKYHFLD-TMFILMLFGWSIIPFIYLLSFWYNNSTNAY------IKIF
VFNHCLG--------FISIIVDAVVQII----PDIKTSTKNLILNSMLLLPIYNFGMSIY
KYYN-------------IHEIRK-LCSSLGY-INTIPS----CKSQ--IIDIPIYSMNQK
AIGRH--VTAMA---------------ATGLIYFILII

ENSGT00760000118965_2_Linker_2_3 (1719, 1816)

LLETTS-WNLKIFIYRYVLFG-
IYRIFYKA---RMSEE--LSGYSEEEDV-----QNERETILNHPW---RSLNSTVLIKEL
IKIYFKI--PPTLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISVAIQKEE-CFGLLGLNGAGKTTTFKILTGEEIATSGDVFIE
GYSITRNILKVRS-KVGYCPQFDALLDYMTSREILTMYARV-WGIPENSIRAYVDNLLKM
LYLK-PQADKFIYTL---SGGNKRRLSTAIAIM---------GNSTVVFLDEPSTGMDPL
ARRMLWNAVIKTRESGKVIII--TSHSME----ECEALCT-----RLAIMVQGKFVCLGS
PQHLKNKFGNIYTMTIKFKT-------DTDD---NTVQDLKDFIAEV----F--------
-P-GSDL-----KQENQGILNYYIPSKNNSWGK--VFGILEKAKEDYNLEDYSISQITLE
QVFLTFANPDNPRSGYEKAVP---------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASPA
SKKLLLLLWKNFTL---KRRKFGALVTEIILMLAFSIVLLTTRHLLS-INKM--------
----------------------ESLHFPD--QPVGAVPFFFRVSA--NSS--RPWELAYV
PSN--ITVVHNIVENVKKDL-------NFPMAVIGFPSES-------DFEDYARSSVN-S
RNILAAIVFDHNFANSRDPLPKKIKYNLRFSDIKKNIH-G----MAYYQGHTWLTKFLFP
PL-RIVGPRNPQEA--DGGSPGYITEGFLAVQHALDKAIMLHHGGAAATALFNDVS-LFI
QRFPYPAYYHDHFY

PF12698 // ENSGT00760000118965_2_Domain_0 (375, 665)

LFANTFVPLTVASIFFLNHLILVWSIVWEKENRLK-----------
----------------------------EYQLMIGLRNWMFWIAYFFTFFCLYFINIIFM
CIVLFVKID-P-----APIFQYNDPILV----------------------------FILL
LFYAISSIFFSFMISTLFNRV---SFAVSLGSFLFFLTYLPAITMNQSFEHMPPRQKLIW
SFDFNVGMAFGFRFLVNAETR-KTGMKWNNIFLPTDS-DSLLFTYVLGMLLVDAFIYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGEYGVPKPWN-FFL------MHSY-WFGESRQQ--KP--EITQFCKRVE
SKYFEVEPTDLTAGI-QIKH-LHKVF-QENNITKVAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

NDLSLNVYE---GQITVLLGH-N
GAGKST--TLSILSGLYPP-TSGEAYVHGEDISQHMDQIRNFLGLCPQQNLLFDHLTVSE
HLYFYCRVKGVPQNM-CLEETNNMLSAFNLTEKRDAFSKSLSGGMKRKLAIIIALIGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1260)

SGMDPASRRSTWDVVQTYKQNRTILLTTHYMDEADMLGDRIAIMVQGT
LRCCGSSVFLKRL-YGVGSHIVMVKEPVCDVDEISK---LIHYYIPTATLK---TNVGNE
LSFILPKEYTHKFE---A-LLTALEENQENLGISSFGMSITTMEEVFLR--VSKMEDSKP
DMEAT--QSPS--AGS-KG---NRNRDVES-S------------------MRAG------
--FPTQSEDQTIVFNTGCPLYLQ-QFHAMFMKRLMYNWRNWRVLS-VQILGLVISTFLLL
KSHEFR-------HK--RIRQMNLDDYGQTIV---PFSILGKSN-------LTTSLLIH

PF12698 // ENSGT00760000118965_2_Domain_2 (1260, 1718)

L
ENMLKPGNHQLKE-VQ-----GDLLKYL-----EGNEECIHLCIVALSIKVAAGRAKLTV
LFNNEAYHSP-----------------------------SLSLAVLDNILFMSLSGANAS
ITVFHKPQPRPTSKEW----PR------STYGKIVAFKIQLGMALLV---------SG--
FCILTVTERITKAKHMQFLSGASVLVYWLSALVFDFIIFFIS-----CCFLL--------
VMFKYYKIDIYVTDYHILE-TMLILILFGWSAIPLTYLMSFLFSKSIPAY------IQLL
VFYYLSG--------TSGLLIDT--IIEAGLSTIISNSTQTFLLSSLLFFPTYNLGKCIS
EYTV-------------IYQRKI-LCIQQKN-VLKYLN----CSKE--YTKKNIYSLKKP
MIGKY--LIAMS---------------IAGFVYLLFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENIS-WKLRMLIHQHIYFG-
VCKKYKSD---IISNE--LSGTSEDNDV-----ENERREILYQPE---KFLNCPVLIKQL
TKIYFKS--PLILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQERE-CFGLLGFNGAGKTTTFQILTGEITPTAGDVFID
GISITKDVLKVRS-KIGYCPQFDALLEYLTGWEIMVMYARI-WGISERQIRPYVNTYLNS
LELE-PHANSLISTY---SEGNKRRLSTAIAMM---------GKPSVIFLDEPSTGMDPR
ARRLLWDAVIKIRESGKAIII--TSHSME----ECEALCT-----RLSIMVHGKLTCLGS
PQYLKNKFGDIYILKTKVKS-------G------ETLKEFKNFITLT----F--------
-P-GSEL-----KQENQGILNYYIPSKDNSWGK--VFGILEKAKEQYDLEDYSISQITLD
QVFLAFADQDRK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASWE
SRKLLLLLWKNFTL---KRRKFGTLVSEIVLVLLLSIVLLTTRHLLS-IKKI--------
----------------------EALYFPD--QPISTVPSFFRASV--TSF--YPWELAYV
PSN--IMVVENIVKNVKNDL-------NLHMKVIGFPSES-------DFEDY

PF12698 // ENSGT00760000118965_2_Domain_0 (233, 665)

ARSTVN-S
RNILAAIVFGHNFANSSDPLPKKVKYYLRFSDIKKNIN-S----GAYYQGDTWLTKFLFH
SL-RLVGPRNPYEA--DGGSPGYITEGFLAVQHALDKAIMLHHGGADAAALFNDIS-LFI
QRFPYPAYYHDYFYLFATTFIPLTVACTFFFNHYVLVWSIVWEKENRLK-----------
----------------------------EYQLMIGLRNWMFWVAYFFTFLCLYFINIIVV
CMVLFVKIE-P-----APIFQYNDPTLV----------------------------FIFL
LFYAISSIFFSFMVSTLFNKV---SLAMSLGSFLFFLTYFPAVAMHQSFEHMPSKQKLIW
SFDFNVGMAFGFRFLVNADAK-KTGMKWSNIFLSTDS-DSFLFAYVLGMLLADAFIYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGEYGVPKPWN-FFL------MHSY-WFGEPPQQ--KP--EITQFYERVE
NKYFEAEPTDLTAGI-QIKH-LHKVF-QKNNSTKVAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQVTVLLGH-N
GAGKST--TLSILSGLYPP-TSGEAYVHGEDISQHMDQIRNSLGLCPQQNLLFDHLTVSE
HLYFYCRIKGVPQKM-YLEEINNMLSAFNLMEKCDAFSKSLSGGMKRKLAIIIALIGGSK
---V-AILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1301)

SGMDPASRRRTWDILQTYKQNRTILLTTHYMDEADVLGDRIAIMVRGT
LRCCGSSVFLKRL-YGVGSHLVMVKEPYCDIAEISK---LIHSYVPTATLE---TNVGNE
LSFILPKEYTHRFE---A-LFTALEENQENLGISSFGVSITTMEEVFLK--VSNLEDSKT
DIEAT--QSPS--VGS-RG---SKNRDVES-S------------------RRVG------
--FPTQSEDQNIVFNTGCSLYLQ-QFRAMFMKRLMYNWRNWRGIL-VQILGLVISTFLLL
KSHEFR-------YK--KIRQMNLDEYGQTIV---PFSIWGKSN-------LTSSLLTHL
ENMLKPGNHQLKE-VQ-----GDLLKYL-----EGNDECI

PF12698 // ENSGT00760000118965_2_Domain_2 (1301, 1718)

QLCIIALSIKVVANRVNLTV
LFNNEAYHSP-----------------------------SLSLAVLDNILFMSLSGSDAS
ITVFNKPQPSPQRIEW----PG------STDGKIVAFKIQLGMALLV---------SG--
FCILTVTERHNKTKHMQFLSGVSILVYWLSALVFDLIIFFIS-----CCFLL--------
VMFKYCKFDIYVTDYHILD-TMLILTLFGWSAIPLTYLLSFLFSKSNSAY------INLL
VFCYLSG--------TLSLLMDT--IIEARISTIMSNSTQTFLLNALLLFPMYNLGKCIS
EYTV-------------IYRKKM-LCIQQKN-ALKYLN----CSNK--HTKKNIYSLKKP
MLGKY--LIAMS---------------ITGFVFLLLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENIS-WKVKMLIHQHIYFG-
ACKKYKPD---IISKE--LSGTSEDNDV-----ENERREILYQPE---KFLNCPVLIKEL
TKIYFKS--PLILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQERE-CFGLLGFNGAGKTTTFQILTGENIPTAGDVFID
GISLTKNIVKVRS-KIGYCPQFDALLEYMTGWEIMIMYARI-WGISEHQIQPYVKKYLNS
LDLE-SHANSLISTY---SEGNKRRLSTAIATM---------GKPSVIFLDEPSTGMDPR
ARRLLWDTVIKIRESGKAIII--TSHSME----ECEALCT-----RLSIMVRGRLTCLGS
PQYLKNKFGDIFILKTKVKS-------G------ETLNEFKNFITLT----F--------
-P-GSEL-----QQENQGVLNHCIPRKNNSWGK--VFGILEKAKEQYNLEDYSISQITLD
QVFLSFADQDRK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------KRKTFITVLEILMPLIFSALVLYLRFSSI-PKTK--------
----------------------PPTSYHP--IDVSSLPEFFYNYP---LK--TKFQLVYI
PSR--SETLKALTEIVEQTF-------DVEFEVLGFSSES-------LFESYILKDPK-A
FYALVGIVFGHNFSDSNEPLPLSVEYSLRFSYIQRNLLSLK-HVYFQADLEGWCTSFLYP
PN-PSQEPREIVYA--DGGTPGYHKEGFLAIQHAVDKAIMWHHAQNATVNLFESLS-VLL
QRFPYGPHVQDKFFMLLQNEFPLLLMLSFICIELIIINSITLEKERKLK-----------
----------------------------DYMCMMGLDSWLHWIAWFIMFFISVLIAVSVM
TVLFCTEVH-I-----SCSLGSTALLLA----------------------------FWWL
IEDKSLTD----------------------------------------------------
------------------------LSAWSIFE---PLSSDLSL-------------LT--
RYCWLTSVILSGRMRS--------------------------------------------
-------------------------------------ED-------------CILIFF-W
GGPVTLGCFFY

PF00005 // ENSGT00760000118965_2_Domain_1 (792, 913)

LVLGLTVP-SSGQAYINGYDISTDMVQIRKSMGWCPQKDILFENLTVAE
QLSFYAQLKGLSPQK-CPEEVKHMLYALNMEDKRNSPCKYLSGGMKRKLSIGIALIAGSK
---L-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1297)

SGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMADGE
LQCCGSSLFLKQK-YGAGYYMTLLKTPFCDTQKLCR---LIYHHIPNAVLE---SDVAEE
LIFILPKESTHRFE---S-LFADLELNQSELAISSFAASVTTMEEVNTF--FYFYFC---
------------------------------------------------HSWVL-------
-----NSGTLPLELQHHFPFSG----------------GLFKIRV-SQPLLP--------
---------------------------------------RLALN-------CDPQIS---
---------CSAS-LA-----DPIEEFLLRKAKEEP

PF12698 // ENSGT00760000118965_2_Domain_2 (1297, 1638)

ENFDRLYVVAASFEVKDNATIVTA
LFNNQAYHSP-----------------------------AVALALVDNLLFRLLSGASAS
ITTSNYPQPQTEEELSESL-LYQ-----GAKGYYLIVNLLFGIAFLS---------SS--
FSILTVRERCMKSKQLQFVSGVCITAFWFSALLWDLISSLIP-----TLLLM--------
VVFLYYNEEALTQHGNAPA-VVLMLMLYAWAIIPFIYMISFSFDNAGNAC------VKLV
IILTFLS--------IGPT--VL-VLAT---SLGYTEIS-QSLDHVFLIFPGHCLGMAFS
NLYY-------------NFELKK-FCSAKNLSDTECNEVCEYNE----------WNFSFC
GHGLF--SSRLV--------------------------------LYHLSHSATSG-FFL-
-----------------------------------------------------------F
AYVFDQK-D---------------------------------------------------
----------------------------------------------------------SP
LQMTILHDSSSPSPI---SGGNKRKLSIGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCVGS
PQHLKSKFGSGYSLQAKVHS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGLVCYHLPGHNLCLSK--VFGSLEKAKRKYKLEDYSINQVSLE
DVFLSFTNPIQPTQRKDQAQA---DSSLSLPPPPPA-----QP------------SSPSS
SHLSIF-PT---------------------------------HLFQP---PLHPPP----
-----SSNTILL---------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------VNKLAAPQR
NIQTL--NSCYLAYKK-MRQDKQQNVNIPRNY------------------KGPD------
--FSYLSEISTTKFNTGFPLYRQ-QFRSMFIKRALFIWRNWKLML-LQITVILLATTYLL
LALHSD-------DHDIPERELDLSHYGETIV---PYSISGNSD-------LALNLTENL
KKFLKLKNQNLRK-IR----

PF12698 // ENSGT00760000118965_2_Domain_2 (1281, 1719)

-GDINDYI-----LKNKECRSFCIIALSIEVKKNKTVLTV
FFNNEAYHSP-----------------------------AISLAILDNILFMTLSGPNAS
ITVFNKPQPQPHPYYDSNT---M-----TVSGLQIVQCLAFGISVVV---------GT--
FSLQTVTERISQAKHIQFLSGVCVLTYWLPAFLCDLLFFFIA-----SCILL--------
GVFIFCQVDAFFVSYNFLD-TMLIFMLYGWCAVPLMYLGSFLFRSSTTAY------IKLT
LFNYFST--------IFSIIIYTIVKFYG---SDFPKFINSFINTALMILPSYNFAMCIS
KYFD-------------DYEVKT-LCAKEF--RSIYMD----CSES--YTQNNVYGFEER
GIGKF--LITLA---------------AMGLVFLLLLL

ENSGT00760000118965_2_Linker_2_3 (1719, 1816)

YLETIS-WNLRNFVFRNIIFY-
FYNKFRKGRQ---SNQ--GIKEDEDEDI-----RRERRKVLTLM---LRSQKTPLVLKEV
TKIYFKC--PVVKAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLAVRRSE-CFGLLGLNGAGKTTTFKMLTGEEAITSGVALID
GNSVAGNPRKIRS-RIGYCPQSESVLNHMTGRELLIMYSRL-WGVPEEDINKYVETFLHS
VHLE-HFADQFIYTY---SGGSKRRLSTAVALM---------GKSSVVFLDEPSTGMDPV
AQHLLWDTVTWICKTGKAIII--TSHRME----ECEALCT-----RLAIMLKGRFTCLGS
PQHVRKRFGHVYTLTVKINI-------AKDE---DKIAEFKKFIQTT----F--------
-P-GNIK-----NQEFQGIIGYYIPSKEVCWGK--VFEIMEEAKVLFNLEDYSVKQVTLE
QIFLTFANTDKMRGFSEIIML---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLTIQSENVP--------
----------------------NATVYPD--QNIQDLPLFFTFPP---PG--GTWELAYI
PSH--SAAAKTITESVRGAL-------VINMRVHGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFENISNHSKEPLPLTVKYHLRFSYTRRNYMWTQTGNFFLKDTEGWHTTSLFP
LF-PSPGPREPASP--DGGEPGYIHEGFLAVQHAVDKAIMHYHANASARQLFQKLT-VTA
KRFPFPPFISDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSNWLHWSAWFLVFFLLLLITVSFM
TVLLCVKVK-ND----MAVLARSDPSLV----------------------------LVFL
LCFAVSSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLNQKLVS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWKNLLSPVNVDEDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------LPSY-WCGNPRMVMGKEE-EDCDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKEKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYIGGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLCFYAQLKGLSRQK-CPEEVKQMLYILNLEDKRNSLSKFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKNDRTILLTTHFMDEADLLGDRIAIMAQGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPKAISQ---LVYHHIPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFSKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGAL-
----IEEEHSIVQLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCITLAL
LAINYSSEI-----FDDPMLRLSLSEYGRTIV---PFSVPGTSP-------LDQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERFLVAVSFKDEVKKTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSTLQAAKDQ-FSE-----GRKGLDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGIRVATFWLSALLWDLISFLIP-----ILLLL--------
VVFRAFDIRAFTQDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------SRLT
IFNILSG--------IATFLI---VTIMRIPALKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSKVATQ-------YCKKYNIEYQENFYAWSTP
GVGRF--VTSMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNILWRLRTFICAF-----
-WRRW---M--LTELHSRISVVPEDLDV-----AQERSRVLTPSLDSL--LDTPLIIKEL
SKVYEQQ--APFIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGACVENTLRG
LLLE-PHANKLVRSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRT-------DGQQ---EALEKFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHNLSWAK--VFGVLEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MKV
FRNLKLLLWKNFIL---KKRKPLITVLEILMPVLFSTVVMYLRFNSL-PRKR--------
----------------------PSSNYQP--VDISSLPGFFYHYP---VK--NKFQLVYI
PAR--SEALKNITEMVGESF-------DVDFEVRGYHSES-------AFESYVINDPS-A
FYILTGIVFDHSFNDSKDSLPLSVSYSLRFSCIMRNFLFLR-VIVPQDYVEGWSTSFLYP
PN-PGDEPRDHAFN--DGGSPGYHKEGFLAIQHALDKAIMWHHGKDAMTKMFANVS-VLV
KRFPHGPYIQDHFFLVLQNEFPPLLMLSFICIELTIINSIVLEKERKLK-----------
----------------------------EYTCMMGLHNWLHWVAWFIMFFISIFIAVSLM
TVLFCTKIP-D-----LAVFNNSDPSLI----------------------------FVFL
MCFGVATLFFAFMASTFFTKELVAQVATATGGVTFFFTYLPYLYITFSYTQRSHLQKIAC
CLFSNVAMALGIRFISLSEAK-GVGLQWRNIG---GINGDFNFAQVLLMLLFDSFLYG--
LVAWYLESAFPGANGIPKPWY-FFV------MPSY-WQGKPIPPTHSM-LQIKDSKEALK
GVFIQEEPIGLMKGI-EIQH-LYKVF-HKGRNKNIAVKDLTMNLYR---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TCSMLTGLLPI-SSGRVYINGYEISEDLVQVQKSLGWCPQHDILFYDLTVSE
HLYFYARLKGLSLQK-CREEVQEMLHTLDLEDKQDSPSKFLSGGMRRKLSIGIALIAGSE
---V-LMLDEP-SGMDAISRRPSGTCSSSRKSDRTIL-PTNFMDEADLLGDRIAIMAKGE
LQCCGSSLFPQAEIRRSGYYMTLVRKPQCDTEEIAH---LIYHHVPNAVLE---ASMGEE
LTFILPKDSTHRFE---S-LFSDLERRQEELGISSFGASVTTMEEVFIR--VNKLVECTA
DTQDF--LSADGPAHR-AEHRVKIL----ATPLIS-------KNCCDLFDPMLGFGD---
--SSKSSREVFLSVQSQFYLFCQ-QFYAMFLKRMTYSWRNWAMMLSVQILVPLVIVIFSL
MSFNLKASS---M--ENVPLKLTLKTHGQTIV---PFFISQNSS-------LSSRLSKHF
TDMLEAELQIPLE-VS-----GPVEEFLLQKAEEEPEGFDNRYVVAASIEDVKGRTVVTA
LFNNEAYHSP-----------------------------ALAVALVDNFLFKLLSGAKAS
ITATNHPQPQTAIETSEDI-LYQ-----GLKVHYLVINLLFGMAFLS---------SS--
FSILTVKENSSKAKHVQFVSGVHVVTFWLSALLWDLISFLVP-----SLLLL--------
VVFLYYKEEAFTCNGNILA-VFLMLMLYGWAIIPFIYLASFCFTNTCNAF------VKLI
IMLTFLS--------IGPF--IL-VSVTSIPPTELQKIS-ESLDDTFIVFPGHCLGMAFS
NLYY-------------NFGFRK-FCNAKKLNKTDCIQAGEYCKTEGYVVQENVYAWESL
GMGRY--VTALA---------------ISGSVYIILLFLIETNTLRRLRAR-VSG-FFR-
--KQN---LASISQLGESLALVPEDQNV-----TEERKAVQSHLENLH--EKNPLVVKEM
SKVY-FT-EMPLLAVDKVSFTVQV

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

AE-CFGLLGINGAGKTSIFKMLTGEELITSGDAFIQ
GFSINSDLRKVWQ-YIGYCPQLDALLDHMTAQETLVMYARL-RGIPECYIRACVDHMLDE
LLMY-KSANKLVHTY---SGGNKRKLNAIAALI---------GDPAVIFLDEPSSGMDPM
ARRLLWDTVVRARESGKAIIF--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSSYSL-AKVQV-------DAQK---VVLEEFKAFMHLT----F--------
-P-GSIL-----EDEHQGMVHYHLPSHGLSWAK--VFGTLEQAKEIYALDDYAVSQVSLE
DIFLSFASPAPPSQGA--------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MVV
LRQFGLLLWKNYIL---QKRQILVTLIEICLPLLFAAILIALRHRVHSISHP--------
----------------------NATIYPS--QSVDELPWFFHRW----HP--RPWELAYV
PSN--STAVRRIAEVVEKAL-------HVNIKAHGFPSER-------AFEDYMKFDNR-S
GNVLAALVFKHHFNQSQDPLPLQVNYQLRFKYSPRNAPRSEQTGLNPNLDRDWHTSYLFP
LP-ATLRPAVTSSPHDFTGQPRYLREGFLAVQHAVDIAIMQYHANASAAGLLEGVT-VAV
RRFPYPPYVNDLFLLAIQNQLPLLLMLSFTYTSLNIVRAVVHEKEKKLK-----------
----------------------------EYMRMMGLSNWLHWSAWFLMFFLFLLVSIFFV
TVLFCVKVS-QQ----GAVLTNSDPTLV----------------------------FTFL
AIFSISSISFSFMVSTFFSRA---NVAAAAGGFLYFFSYIPYFFISPRYDLMSHSQKLAS
CLISNVAMAMGAQLLGMFEGK-GE---WQEAQEHESLDREICFQRMC---WRSCLLMALF
LLLTTERSAVPGSWLTPVSLLLALV------LPSY-WCGTPQTALGKEKEEEEDPEKALK
SQYIEEEPADLVSGI-KIKH-LSMVF-KVGNKTREAVRDLTLNMYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLYPP-TSGQAYVNGSSVSRAPCE---------GAARVSQPLSRAL
TPPPRRQLKGYPPLK-CPEEIARIVRLLRL-------SKALSGGMKRKLSIGIALIGDSK
---V-VMLDEPTSGMDPASRRATWDLLQQQRSSRTILLTTHFMDEADLLGDRIAIMAQGE
LQCCGSSLFLKHK-YGAGYHMVMVKEPHCNLGEISR---LVCQYVPNATLE---SNAGAE
LSFILPTESTHRFE---A-LFTELEQKREELGIASYGASVTTMEEVFLR--VGKLVDSSM
GIQAI--QLPALQYQH-ERRSNDWAVDDSSSL-------------SGMT-DMTDDSG---
--ALITEDCSSIKLNTGFYLCCQ-QFYAMFMKRAVYSWRNWKMVA-AQFLVPLIFTTLAL
AVAKTFPGP---R--DSALLRLTLDPYGRTVV---PFSAARGPMGALLSGALPSSVGCFL
PCKVS----------------------------PLAEGWADREGPARLQAQLGGRD----
------SSVLCS---VKESFAFILSK-------ESITDPVKAVPLADNALFRLLAGPNAS
ITVTNYPQPRNITETAKDQ-LME-----GQTGFAIAINLLYGMASLS---------ST--
FALLLVSERALKAKHVQFVSGVYVANFWLSALVWDLINFLVP-----CALML--------
FVSGVYVANFWLS-------------ALVWDLINFLVPCALMLAVPSAGR------ERLR
IPSFCLAPKGRFLFPPRAGISQL-APPGRCPELGLLDLS-RTLDKIFLVLPNYCLGQCIS
DFYQ-------------NYEFIQ-FCTSSVEAIIICKAF----------XQKNYFSWETP
GIGQY--LTSLA---------------AQGTAFLLLLFFIETNLLWRLRTV-VC----G-
VCRRR---KWALLLNRT--PVLPEDRDV-----ADERKKVLESPPELLSSLSSPLVIKEL
TKVYDTQ--ESLLAVDRISLAVSQGE-WFGLLGFNGXGLMFWA-----------------
-----CLGSQVQQ-RIGYCPQFDALLDHMTGRETLSMYARL-RGIPERYIGSCVENRLRG
LLLE-PHADKLVRSY---RGSENLRSRPRLAEKFWPASSFLPGFPSDPWRHFPCPGGAGG
----------GQRSLGEALVLGCANLFME----ECEALCT-----RLAIMVNGQFKCLGS
PQHLKSKFGSGYTLLAKTRA-------E-EE---GDVQVFKAFVEKT----F--------
-P-GSVL-----KHEHQGMVHYHLTSKNLSWAQ--GFDRMESAKEKFRVEDSSVSQISLE
QVFMSFTRFQHCAEERGK------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------GYFAEGFLTIQHAINKAIMRYHAKNTARDLFNITS-VFI
RRFPFPVSSADNFYPIFIFFLPLTIILVFSVIVFNMIRFVMLEKESMLKVAILFF-----
-------YASKCFLIPEKNTFDCFSEKKEYLCIMGMSNLMLWSSYFFTYFLFFLFIIIVL
TLILLAKIV-Y-----LPIIIYSEGSLV----------------------------FFFL
MCSAIVSIFFSFMISTFFNKT---TTAVALGGFLYFLTYLPYSFIHSYYKVMSLNKKLLS
CLFSNVAILLGIQILISSEIT-ENGISWTKLTQPVTRNENLTFGHILGMLIFDSFLYA--
VVTWYIQAVFPGNLGIPQPWN-FFL------MKSY-WYGTSAATVD----KNTETYITFE
NPYIEEEPVGLEVGI-QIQN-LSKVF-ITNNIKKYAVNDLTLNFYK---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--ILSMLTGMLPP-TSGEAYICGYEISKSIVQVRESMSFCPQYDILFHYMTVAE
HLYLYGQLKGLTRKE-CRKEIKQTLKFFDLEEKHDDYPKSLTAGMKRKLSLCITLLGGSK
---V-IILDEPTSRMDPITQNNTWELLQQYKQGHTIVLTTHNMEEADVLGDRIAIMAKGE
LQCCGSSFFLKHK-YGVSRL----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLQ
MRQFSVLLWKNFLL---KSRNVVGLVVEIILIFLLFVWTLTVRRISK-KTSI--------
----------------------SDVIFNP--ILLT-LPKFLN------EN-

PF12698 // ENSGT00760000118965_2_Domain_0 (172, 663)

-FDYELAYV
PSE--SNAARNITEMVKKDL-------NFNFKVQGFPSEE-------SFERYIKYENK-D
AHVLAAIVFDHKFKTSNERLPLQVKYSLRFGRIYDPENLFQ--PSKYQKEIEWNTSTLFP
SV-PSLGPRNFLEN--DGGNPGYIREGFLIVQHSVDKAIMMYHSGRAAEAIFANTT-IYA
ERFPHPAFIHDSFLWTFIAMFPWTILFTFTQMALVIVGTIMLEKEKRLK-----------
----------------------------EYQLMVGLSNAMLWVSYFVTFLLMYFIIICLL
CGILFLKIT-H-----ERVFQHSDPLFI----------------------------AFYF
MCFAVSSMLLGFLISTLFNKA---SLATSIAGFLHFLTFFPYLILYHKYDQISLSGKLAL
CLITNTALAFGTDLICKLEMK-GHGAQWNNFATKVNADDDLTLAHIIGMFLFSAFLYG--
LV

ENSGT00760000118965_2_Linker_0_1 (663, 758)

AWYLDAVFPGTYGVPKPWN-FFL------QKSY-WFGEPALS--R---EESQVSDLLS
NDFMEPEPVGLVAGI-RIQH-LYKEF-ILKTSTVMAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

NDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSILTGLYLP-TRGKVYISGYDISSDMVQIRKSLGLCPQDDLLFPMLTVSE
HLHFYCVIKGIPSQN-QSRETNRMLTSFGLLQQSNTMSKDLSGGMKRKLSIIIALMGDTK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1186)

SGMDPVSRRATWDILQHYKKDRTILLTTHHMDEADVLGDRIAILVMGI
LKCCGSSLFLKKL-YGVGYHLVIVKTPDSDDEKIFQ---LIKNYIPTAKME---TNVAAE
LSFILPKEHTHRFA---E-LFTDLEKKQEVLGISGFGVSMTTMDEVFFK--VSNLEDLKL
NTEIA--PSASKVSQ--SSNEDNQNMNVPRKF------------------ERP-------
--GY-SRRHLDSSFNTGWSLYIQ-QFRAMFIKRVMFSWRYWKLLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1186, 1718)

-LQLLALLGLMYLLI
KGISFS------A-PTEPARVMDLEQYGETIV---PFSVSGDPN-------LTQILTKNL
EIMLKAKKQKIHE-VQ-----GDMKNYL-----LTSKDCIYSCIVAFSLDVSTEEKTLIF
WFNNEAYHAS-----------------------------PLSLSILDNIIYKHLSGPDAT
ITVSNNPQPQRVTKDKS---DER-----SISGIQIVFNLLFGMSIFT---------SG--
FCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIIHFVA-----CVLLL--------
IVFLYTDVDILLEKYHFLD-TMFILMLFGWSIIPFIYLLSFWYNNSTNAY------IKIF
VFNHCLG--------FISIIVDAVVQII----PDIKTSTKNLILNSMLLLPIYNFGMSIY
KYYN-------------IHEIRK-LCSSLGY-INTIPS----CKSQ--IIDIPIYSMGQK
AIGRH--VTAMA---------------ATGLIYFTLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

IFLETTS-WNLKIFIYRYVLFG-
IYRIFYKV---RMSEE--LSGYSEEEDV-----QNERETILNHPW---RSLNSTVLIKEL
IKIYFKI--PPTLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISVSIQKEE-CFGLLGLNGAGKTTTFKILTGEEIATSGDVFIE
GYSITRNILKVRS-KVGYCPQFDALLDYMTSREILTMYARV-WGIPEKSIRAYVDNLLKI
LYLK-PQADKFIYTL---SGGNKRRLSTAIAIM---------GNSTVVFLDEPSTGMDPL
ARRMLWNAVIKTRESGKVIII--TSHSME----ECEALCT-----RLAIMVQGKFVCLGS
PQHLKNKFGNIYTMTIKFKT-------DTDD---NTVQDLKDFIAEV----F--------
-P-GSDL-----KQENQGILNYYIPSKNNSWGK--VFGILEKAKEDYNLEDYSISQITLE
QVFLTFANPDNPRSGYEKAVP---------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAM
FRNLKLLLWKNFIL---KKRKTLVTVLEILMPLLFCAVIIYLRFGSL-PRKR--------
----------------------PPVDYKV--IDITSLPEFFNQFP---LK--NKFQLVYI
PSK--SETLKNITEMVKDFF-------TVEFEVLGYPSVP-------VFEKYIIQDPK-A
FYVLTGIVFDHNFNDNTEPLPLEVKYYLRFSFFQRNYLSLR-LILQQDDMQGWLTSFLYP
PN-LSQEPRDYGVS--EGGAPGYYQEGFLAIQHATDRAIMWHHAPTETTGLFQSLS-VLL
KRFPHGAYVRDIFFLVLQNEFPVFLMLSFICIELITINSIVLEKERKLK-----------
----------------------------EYMCMMGLHSWQHWVAWFIVFFISASIVVSFM
TLLFCIEFD-E-----SAVFGNSDPSLI----------------------------FVFL
MCFAIATIFFAFMISTFFQKA---HVATASGGIIFFFTYLPYLYIAFTYSQRSSFQKIAF
CLLSNVAMALGVRLISTFEAR-GTGVQWRNMG---HIGGEFNFTQVLLMLLLDSVLYG--
LVAWYVEAIFPGEYGIPKPWY-FFL------TPSY-WWREPTSLRNPV-EDLEDPQQALG
NKFIQDEPTNLIKGI-EIQH-LYKVF-YKGRDEHVAVKDLTVNLYQ---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TCNILTGLTTP-SRGQVFINGYELSKDMLQIRKSMGWCPQHDILYDNLTVAE
HLYFYAQLKGLPRQK-CPEEVKRMLHVLGLEEKRDSRSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPTSGVDAISRRAIWDLLQQHKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKEK-YGAGYYITLVRKPHCDTEKISL---LVYQHIPNAVFQ---SSIGEE
LTFILPKESAHSFE---A-LFTDLELRQEELGIASFGASVTTMEEIFIR--VNKLMDSDI
DLQII--KLPSFHSHP-LDQPNESILQNNEIGFRG-------LR--ASVGAL--------
--LEVE-SLLFDWVDVKFSLLCQ-QFYAMFLKRATYSWRNWIMMLSIQILVPLVILSISL
SFLNFDI-S---M--DNSPLELTLKSYGQTIV---PFYISPNSR-------LGPRFLDHL
TDVLMAEDQKPLE-LQ-----SPVEAFLLKKLEEEPEVFDQNYLVAISFDDMENHTVVTA
LFNNQAYHST-----------------------------AQALALVDNVLFKLLSGPSAS
ITVLNHPQPESSMETAEDI-LYE-----GPKGHYLVINLLFGMAFLS---------SS--
FSILTVKERGLKAKQVQFISGVHVATFWLSSLLWDLLSFLVP-----SLLLL--------
VVFLYYDEEAFTHKENVRA-VFLMLMLYAWAIIPFIYLTSFCFENAGNAC------VKLI
IMLTFLS--------IGPF--VL-VSVTSEKDLGYTEIS-ESLDNTFLLLPGHCLGMALA
NLYY-------------NFELQK-FCKVKSLDQIECSKF-----YNVVLVSEDIYAWESL
GMGKY--LIALA---------------ISGLVYLILLFLIETNVLWELKAR-FSG-LY--
-WKQK---LEKQV-VLQNAESVPGDQDV-----EEEAKMIKNSWEDLC--KKNPLVLKEL
SKVY-SR-KVPPLAVNKVSFTVQAEE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTIFKILTGEESITSGDAFVN
SISVSSDLRKVRQ-WIGYCPQVDALLDHMTGKETLVMFSRL-RGIPERHISSCVDQILDD
LLMY-TYADKLVKTY---SGGNRRKLSAGIALL---------GEPVVIFLDEPSTGMDPV
ARRLLWGTVARARKSGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVGLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDELSWAK--VFGIMEQAKTMYMLEDYSVNQISLE
DIFLSFSCPVPPAQGSNR------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTWYMEAVFPGQFGVPQPWY-FFI------LPSY-WCGKPRAVAGKEE-EDSDPEKELR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAVRDLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPTSGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPSDGIGAL-
----IEEEHTAVKLNTGLTLHCQ-QFWAMFLKKAAYSWREWKMVA-AQILVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTIV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHVAD-TLLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSEVAAH-------YCKKYNIQYQENFYAWSTP
GVGRF--VASMA---------------ASGCTYLILLFLIENNLLQRLRGILCAF-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQR--APLLAVDRISLAVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEESPTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEDFKAFVDLT----F--------
-P-GSIL-----EDEHQGMVHYHLPGRDLSWAK--VFGILEKAKEKYSVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------SG--
FCLLTVTERVTNAKHIQFVSGIYVLIYWFSALLWDFIIFFIS-----CCLLM--------
GVLKYCKVEVFFIEDQLLD-TMLIFMLYGWSAIPLMYLMSFLFSASTTAY------VKLV
LFNYFSG--------IFSLLIDMTLQYSKELETKMSNDTRMRILNTLLLLPNYDLAKALE
NYSN-------------AYQDKT-LCHTLKY-PPPSVN----CSKT--NIEKNVYSLEEN
MIGKY--LITMG---------------VLGFVLFLLIFLWETTL-WKVKTFLGRYVYFG-
IYKKFKQN---TISKE--LSGESEDEDV-----EKERRRVLELPQ---ELLNTIILIKEL
IKIYFKC--PAILAVKNISLRIQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTSTFKMLTGERTATSGDMFIE
GFSITKNILKVRS-RIGYCPQSDALLEYMTGREIMIMYARI-WGVSEPQIHLYVNNWLNS
LQLE-PHADRLIHTY---SGGNKRRLSTAIALM---------GKSSAIFLDEPSTGMDPV
ARRLLWNLITQTRETGKAIVI--TSHSME----ECEALCT-----RLAIMVKGKFVCLGS
PQHLKNKFGHLYILKAKVKP-------DIGE---DKLEDFKIFISTI----F--------
-P-GSVI-----KQENQKIINYYIPSKDNSWAK--VFGILEEAKEQFNLEDYSISQITLE
QVFLTFAYPDKTE--DEYKKN-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIRELPLFFSFPP---PG--DTWELAYI
PSQ--SVAVKTVTEMARRTL-------VINMRARGFRSEK-------DFEDYIKYDNH-S
SNVLAAVVFDHAFNHSRDPLPLAVKYHLRFSYTRRNYMWTQTGSSFLKETEGWHTSSLFP
LF-PNPGPREPASP--DGGEPGYIREGFLAVQHAVDRAIMQYHANASTRQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAVSFM
TLLFCVKVK-KN----VAVLTHSDPSLV----------------------------LVFL
VCFAISSISFSFMVSTFFSKA---NMAAAIGGFLYFFTYIPYFFVAPRYNWMTLSQKLFS
CLLSNVAMAMGAQLIGKFEAK-GTGVQWRDLLSPVNVDDDFSFGQVLGMLLLDSILYG--
LVTWYVEAVLPGQFGVPQPWY-FFI------MPSY-WCGLPRTVFGKEE-DDDDPEKALR
TEYFEAEPEDLVAGI-KIKH-VSKVF-KVGNKGKAAVRDLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKNLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKRMLHILGLEDKRDSRCRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPTSGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNAEGISR---LVHHHVPTATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------HLCGTM-DPTDGIGAL-
----IEEECTAVKLNTGLALHCQ-QFWAMFLKKATYSWREWKMVA-AQVLVPLTCVTLAL
LAINYSSEI-----FDDPLLKLTLDEYGRTVV---PFSVPGTTR-------LDQQLSEHL
KDMLQAQGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
MFNNQAYHSP-----------------------------ATALAVMDNLLFKLLCGPQAS
IVVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAIQAKHVQFVSGVHVATFWLSALLWDLMSFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHVAD-ALLLLLLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-RTLDRVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIQYQENFYAWNAP
GVGRF--VTSMA---------------ASGFAYLTLLFLIEMDLLWRLKTCICAL-----
-RRRR---A--LMEVYTRTSVLPEDQDV-----VDERNRILAPSLDSL--LDTPLIIKEL
SKVYEQR--APLLAVDKISLAVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RIGYCPQFDALLDHMTGRETLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMAQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------DGQQ---KVLEEFKAFVDLT----F--------
-P-GIIL-----EDEHRGMVHYHLPGNDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTEDEGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---KKRKVLVTVLELFLPLLFSGILIWLRLKIQSEKVP--------
----------------------NATVYPG--QSIQELPLFFTFPP---PG--DSWELAYI
PSN--SDAIRSITETVRRAL-------LINLRVHGFSSER-------DFEDYVRYDNH-S
SSVLAAVVFEHTFNHSKDPLPLAVRYHLRFSYTRRNYMWTQTGNFFLKETEGWHTTSLFP
LF-LSPGPREPSSP--DGGEPGYIREGFLAVQHAVDKAIMYHHANASAHQLFQKLM-VIT
KRFPFPPFISDPFLVAI

PF12698 // ENSGT00760000118965_2_Domain_0 (378, 665)

QYQFPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFLLFLFLVVSFM
TLLFCVKVR-KD----VAVLSSSDPSLV----------------------------LAFL
LCFAVSSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPWYNWMTLTQKLSS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------LPSY-WCGNPRTVVGKED-DDSDPEKALR
TEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRLAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSVLTGLFPP-TSGRAYIRGYEISQDMGQIRKSLGLCPQHDVLFDNMTVAE
HLYFYAQLKGLSRRK-CPEEVKHMLHLLSLEDKRDSLCKFLSGGMKRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDATARRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVLHHVPNATLE---SHAGAE
LSFILPKESTHRYV---P-WVVHVQRGARG---------------FDSV--VGKLVDTSM
DVQAI--QLPALKYQH-ERRASDWAVDG---------------TLCGVM-DPTDGIGAL-
----MEEEQAMVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCITLAL
LAINYSSEV-----FDDPPLRLGLDEYGRTVV---PFSVPGTSQ-------LDQQLSEHL
RDMLRAEGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDVGEWTVVTA
LFNNQAYHSP-----------------------------ATALSVVDNLLFRLLCGPQAS
IQVSNYPQPRSVLQAAKDQ-FSE-----GRKGFDVTLNLLFAMAFLA---------ST--
FSILTVSERAVQAKHIQFVSGVRVATFWLSALLWDLLSFLVP-----ALLLL--------
VVFRAFDVRAFTQDGHTAD-MLLLLTLYAWAIIPLMYLMSYFFSSASTAY------TRLT
LFNILSG--------VATFIM---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETQR-YCTSSDVAAH-------YCRKYNIQYQENFYAWSMP
GVGRF--VTSLA---------------ASGTVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLGTFICAF-----
-RRRW---T--LAELHSRTSVLPEDQDV-----AEERSRVLSPSLDSL--LDTPLIIKEL
SKVYDQW--MPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHRISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYSRL-RGIPERLIDACVENTLRG
LLLE-PYANKLVRTY---SGGNKRKLGTGIALI---------GDPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSIL-----EDEHQDMVHYHLPGHDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPVSEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI---------NG--
FCLL

PF12698 // ENSGT00760000118965_2_Domain_2 (1445, 1594)

TVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
VNV-CFA--------------------------------------SIF------------
---------------------------SYSALT

ENSGT00760000118965_2_Linker_2_3 (1594, 1815)

NISNTTRTVVRNSLLLFPNYNLAKCVS
QYTT-------------IYDVKI-LCTTLKK-HPVHLN----CSKA--NTEKNIYSLEEP
MIGKY--LIDMS---------------TAGFIFLVLIFFWETTS-WRLRTFLNQYIYFG-
IYKRYRKE---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLDSIVLIKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIKLYVNKWLNS
LELE-SHADRLISTY---SEGNKRRLSTAIALM---------GRSSVIFLDEPSTGMDPV
ARRLLWNIVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DKLEDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MNWLI
INQLTVLLWKNFTL---KRRQVISSVTEILESLLFVIMLLIFRALTD-INIV--------
----------------------GPYHFTP--QHVATMPSFIKDA--------KEWELIYI
PSD--IDVITEIIENVKKTL-------NTTIKVRGFPSEA-------DFEEYILLDYT-S
QKVLAAIVFDCGFKNKNDPLPLQVKYYLRFVSVQRT--------------IGWKTGFLFP
NH-PSLQTRNPDFL--DGGSPGYIREGFLAVQHALDVSIMLYHESSAGKML

PF12698 // ENSGT00760000118965_2_Domain_0 (352, 664)

FDEIN-VLI
QRFPYPAHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLK-----------
----------------------------EYQLIIGLRNWIIWAGYFFTFFPLYAFIILLI
C-ALLF----FQ----EPILRYSDCSFI----------------------------FVFL
ICYAIASICFAFMISTLFNKT---HLAASAGNLLFFASFFPYNFISKHYGMLNLTSKVTA
CLSANVALALGLNILIKLEIQ-EIGVKWHNLWKPANLEDNLIFGYMFGMLLFDAFLYS--
LVT

ENSGT00760000118965_2_Linker_0_1 (664, 757)

WYIETVFPGQCGVPQPWY-FFL------TRSY-WFGKPKIRKT-E--E-ETTCFSIV
HNCFEAEPTNLVAGI-KIKR-LY-----KEFRNKPA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 912)

VNNLSLNVYE---GQVTVLLGH-N
GAGKST--ILSILTGVYSSPLR--VYINGYNISDNMIEIRKDLGFCPQHDLLFDDLTLSE
HLFFYCRIKGMHQNI-NYKELDRMLSIFNLKDNFHTLSSSMSGGVRRKLSIIIAFSGGSK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1183)

SSGMDPMSRRATWDILQYYKHNRTILLTTHYMDEADILGDRIAIMVRGT
LHCCGSSVFLKQI-YGAGYRIVMEKEPYCNINNIFA---MIQHHVPSAVLE---NDLGNE
LSFILPKKYVSRFE---A-LFTELEINQKILGVANFGASITTMEEVFLK--VNNLAAPQR
NIQAV--KPYYMIYGK-KRQDKQQNVNMPRNY------------------NRPN------
--FPYLSEITTIKFNTGFPLYCQ-QFCSMFIKRALFIWRNWK

PF12698 // ENSGT00760000118965_2_Domain_2 (1183, 1717)

LML-LQIIIVLVVTTYLL
LALNLD-------DDGIPERELDLRQYGGTIV---PYSISGNSD-------LALNLTKNL
KIFLKSKNQSLQK-IK-----GDINDYI-----LESKECHSFCIIALSIKVEKNKTVLTV
FFNNKAYHSS-----------------------------AISLAVLDNILFMTLSGPNAS
ITVFNKPQPL--PYYGSNT---M-------YGLQIVECLAFGISVVV---------GT--
FSLQTVTERVSQAQHIQLLSGVCVLTYWLSALLCDLMFFFIP-----SCALL--------
GVFRFCQMDAFVVSYNFLD-TMLIFMLYGWCVVPLVYLGSFLFHNSTAAY------IKLT
LFNYFST--------IFSIIIYTIVQLHG---SDLPKCISSFIKTGLMILPSYNFAMSIS
KYFD-------------DYEVKK-LCAKKF--RSLHMN----CSEP--YTQNNVYGFGEH
GIGTF--LITLA---------------AMGLVFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LLSLEMVS-WNLKNFVFRNIIFY-
FYNKIRDSRQAAVSNQ--GTK-DEDENI-----RQERRKVLTLSS--LKSQETPLVLNEV
KKIYFKC--PVVKAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISLVVKKSE-CFGLLGLNGAGKTTTFKMLTGEETITSGVALID
GSSVIKNLRKIRS-RIGYCPQSESVLNHMTGRELLSMYSRL-WGVPEQNINGYVETFLHS
VQLE-SVADWLIHTY---SGRSKRRLSTAIALM---------GKSSVVFLDEPSTGMDPG
TQHLLWDTVTWIRNTGKAIII--TSHRME----ECETLCS-----RLAIMVKGSFACLGS
PQHVRKRFGLVYTLTVKINI-------AKDR---DKIAEFKRFIQTT----F--------
-P-GNIK-----NQEFQGIIGYYIPSKEICWGK--VFEIMEEAKVRFNLEDYSVKQVTLE
QIFLTLANTDKMILQ---------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MVV
LRQLRLLLWKNYTL---KKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPD--QHIQELPLFFSFPP---PG--GSWELAYV
PSH--SDAARTITEAVRREF-------MIKMRVHGFSSEK-------DFEDYVRYDNH-S
SNVLAAVVFEHTFNHSKDPLPLAVRYHLRFSYTRRNYMWTQTGNLFLKETEGWHTASLFP
LF-PSPGPREPSSP--DGGEPGYIREGFLAVQHAVDKAIMHYHANASAHQLFQKLT-VIT
KRFPFPPYISDPFLIAIQYQLPLLLMLSFTYTSLTIIRAVVQEKEKKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFLLFSLIVVSFM
TLLFCVKVK-KD----IAVLSNSDPSLV----------------------------LAFL
LCFAISSISFSFMVSTFFSKA---NMAATVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWCDLLNPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGQFGVPQPWY-FFL------MPSY-WCGNPRTVVGKEE-EGGDPEKAFR
TEYFEAEPEDLAAGI-KIKH-LSKVF-QVGNKDKMGI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TMSMLTGLFPP-TSGHAYIRGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSVQK-CPEEVKQMLHTLGLEDKRDSRSKFLSGGMKRKLAIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAVSRRAIWDLLQQQKSDRTVLLTTHFMDEADLLGDRIAILAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVHHHVPNAMLE---SHAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWALDS---------------NLCGVM-DPTNGIGAL-
----IEEEEVLVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WRMVA-AQILVPVTCLTLAL
LAINYTSEI-----FDDPPLKLSLNEYGTTVV---PFSVPGTSR-------LGQQLSEHL
RDMLQAERQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVATSFKDSGERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPRAS
IEISNYPQPRSTLQVAKDQ-FNE-----GRKGFDIALNLLIAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLVP-----SLLLL--------
VVFRAFDVHAFTRDGHMAD-LLLLLMLYGWAIIPLMYLLSFFFSAASTAY------TRLT
IFNILSG--------IATFIV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSEVATH-------YCKKYNIQYQENFYAWSTP
GIGKF--VTSMA---------------ASGGIYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFVCAF-----
-RRRW---T--LAELQNRTSVLPEDQDV-----ADERSRVLVPSLDSM--LDTPLIINEL
SKVYDQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIDACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------EGKQ---EVLEEFKAFVDLT----F--------
-P-GSVL-----EDEHQDMVHYHLPGCDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTTEDGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTLLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATLYPS--QSIQELPLFFSFPP---PG--ATWELAYI
PSQ--SEAVRTVVENVQRAL-------VINLRAHGFASEK-------DFEDYIRYDNR-S
SNVLAALVFEHTFNHSRDPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMHYHANASAHQLFEKLT-VIA
KRFPYPPFI

PF12698 // ENSGT00760000118965_2_Domain_0 (370, 665)

SDPFLVAIQYQLPLLLMLSFTYTSLSIIRAIVQEKEKKL------------
---------------------------KEYVRMMGLSSWLLWTAWFLLFFLLLLVAVSFM
TLLFCIKVK-KG----VAVLAHSDPALV----------------------------LVFL
ACFAVSSISFSFMVSTFFSKA---NMAAAIGGFLYFFSYIPYFFVAPRYNWMTLSQKLFS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWRDLLSPVNVDDDFTFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVLPGQFGVPQPWY-FFI------LPSY-WCGRPRTVLGKEE-EDDDPEKVLR
TEYFEAEPEDLVAGI-KIKH-VSKVF-RVGNKGKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TNGRAYISGYEVSQDMDQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLPRQK-CPEEVKRMLHVLGLEEKRDSRSRFLSGGMRRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1182)

AGVDAVSRRAIWDLLQQHKSGRTVLLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKEK-YGAGYHMTLVKEPHCNPEGISR---LVQHHVPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDG---------------HLCGTM-DPTDGVGAL-
----IEEECTAIRLNTGLALHCQ-QFWAMFLKKAAYSWREW

PF12698 // ENSGT00760000118965_2_Domain_2 (1182, 1718)

KVVA-AQVLVPVTCLTLAL
LAINYSSEI-----FDDPLLKLTLGEYGRTVV---PFSVPGTSR-------LDQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDTGEHTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPRAS
ITVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLLSFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHVAD-ALLLLTLYGWAIIPLMYLMSFFFSGAATAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDRVFLVLPNHCLGMAVS
NFYE-------------NYETRR-YCTSSDVAAH-------YCRKYNIQYQENFYAWSTP
GVGRF--VTSMA---------------ASGFACLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLVEAGLLWRLKTCLCAF-----
-QRRR---A--LTELYPRTAALPEDQDV-----TDERNRILSPNLDSL--LDTPLIIKEL
SKVYEQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DKVSLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSDIGKVRQ-RIGYCPQFDALLDHMTGRETLVMFARL-RGIPERHIGACVENALRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVGLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDGLSWAK--VFGVLEKAKEKYGVDDYSVSQTSLE
QVFLSFAHLQPPTEDAGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVTV

PF12698 // ENSGT00760000118965_2_Domain_0 (87, 665)

LELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATVYPG--QSIQTLPLFFNFPP---PG--GTWELAYI
PSH--SAAAKTITESVRRAL-------MINMRVHSFPSEK-------DFEDYIRYNNH-S
SNVLAAVVFENISNHSKEPLPLAVKYHLRFSYTRRNYMWTQTGNIFLNEAEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIHEGFLAVQHAVDRAIMHYHANGSAHQLFQKLT-VIA
KRFPFPPFISDHFLIAIQYQLPLLLMLSFTYTSLSIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLITVSFM
TLLFCVKVK-KD----VAVLSNSDPSLV----------------------------LVFL
LCFSISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLNQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWQNLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFL------LPSY-WCGHPRMVVGKEE-EDSDPEKVLR
TEYFEAEPEDLVAGI-KIKH-LSKVF-QMGNKEKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFSP-TSGCAYIGGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLCFYAQLKGLSRQK-CPEEVKQMLHILNLEDKRNSLCRFLSGGMKRKLSVGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPKAISQ---LVYHHIPNATLE---SSAGTE
LSFILPKESTHRFE---S-LFDKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGAL-
----IEEEHAMVQLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCVILAL
LAINYSSEV-----FDDPILKLSLDEYGRTIV---PFSVPGSSR-------LDQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVAVSFRDVGEQTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSALQAAKDQ-FSE-----GRKGFDIALNLLFATAFLA---------ST--
FSILAVKERAVQAKHVQFVSGIHVATFWLSALLWDLISFLIP-----TLLLL--------
VVFRAFDICAFTRDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------TRLT
IFNILSG--------IATFLI---VTIMRIPALKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETQQ-YCTSSEVATH-------YCRKYNIKYQENFYAWSTP
GVGRF--VTSMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTLVYTF-----
-WRRW---T--LAELHSRTSVVPEDLDV-----AQERNRVLTPSLDSL--LDTPLIIKEL
SKVYEQQ--APLIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSIISDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPECLIDACVENTLRG
LLLE-PHANKLVKSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDSVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRN-------EGQL---AALEKFKSFVDLT----F--------
-P-GSTL-----EDEHQGMVHYHLPGHNLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDSLR
LKQFAVLLWKNFLL---KRRQGIGLVVEVVLIFLLFAWTLTMRKITK-RSFV--------
----------------------HGITYNG--FSLT-PPAFLLH-----ND--STYEL

PF12698 // ENSGT00760000118965_2_Domain_0 (178, 664)

IYV
PSE--SDVARNITEMVKRDL-------QLNFKVQGFSSEK-------SFEDYIKYENK-S
SIVLAAIIFDHNFKTSKDPLPL--------------------------------------
---------------------KYFKEGFLFVQHSLDKAIMAYHSGSAAENMFANTS-VFG
RRFPYPDYYDDIFLWVFIFMFPWTILFTFTQMELVIVGTIMLEKEKRLK-----------
----------------------------EYQLMVGLSSTMLWVSYFITFLLMYLIIICLL
CVILFLEIV-Q-----ERVLQHSDPTLV----------------------------AAYF
MCFAISSVSLGFMTSTFFNKA---SLAISVSGFLHFLTFFPYLVVYGWYTQISFSGKLAL
CLITNTALAFGTDLICKMEMK-GQGARWGNFFSKVSPDDDLTLAHIMAMFLISAFLYG--
LVA

ENSGT00760000118965_2_Linker_0_1 (664, 757)

WYVDAVFPGTYGIPKPWN-FFL------QKSY-WFGEVPLE--N---IEDQLSEVSQ
SDYVEAEPVDLVAGI-RIQH-LNKEF-TLNNSTILA

PF00005 // ENSGT00760000118965_2_Domain_1 (757, 913)

VKNLSLNLYE---GQITVVLGP-N
GAGKTT--TLSIITGLYLP-TSGKIYVNGYDISTDMAQVRKSLGLCPQDDILFPKLTVAE
HLYFYSVIKGMSYKK-RFKELNRMLTSFGLLQKRDVFSKDLSGGMKRKLSIIIALMGDTK
---V-VILDEPTSGMDPVSRRTTWDLLQQYKEDRTILLTTHHMDEADVLGDRIAIMVMGT
LQCCGSSLFLKQL-YGVGYHLVIVKTPKCDVEKVSQ---LIMDYIPTATLE---MNVAAE
LSFILPKEFSHRFA---K-LFTILEKRKVELGIAGFGVSMTTMEEVFFK--VSNNAGFKV
KNPVG--SLPSIKDQ--SISEENINMNVPRHF------------------ERS-------
--NY-ANERSDIAFNTGWALYTQ-QFQAMFIKRAVFTWRNWKMLF-LQLFALLVLMYLLM
KGVTFP------E-IVDPPRQMDLEQYGETTV---PFSISGDRN-------LVQNFTENL
KTMLKAKKQSLWE-VT--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
-QKLLILLWKNLTL---KRRKFGALVTEIALLLILSVVLLVTQSLLS-IKKV--------
----------------------KSFQYPD--QWASDVPSFIQVFT--TIS--HPWELAYV
PSN--SIMVQNIVENVKKDL-------NFHMKVTGFSSES-------DFEDYIRSNVN-S
RHVLAAIVFDHSFTDSNDPLPKKVKYYLRFSSVKKKMN-S----WAYFQGHSWFTNFLFP
PE-HLLGPRNQFDA--DR---GYISEGFLAVQHALDKAIMLHHGGGAATALFSDIS-LFI
HRFPYPEYHHDFFYTFANIFIPLILACTFFMNYLTLIQSIVWEKGNQLK-----------
----------------------------IV---FKLKIFKVWDAFMWK------------
----PFNLE-P-----APIFQYNDPILI----------------------------FIFL
SFYAISSIFFSFMISTFFNRV---NVAVSLGSFFFLLTYFPCITMYSNYEHMTFKQKLIW
CFNFNVGMAFGFKFLIDAETK-KTEMKWSNICSTGYT-DNFLFAYVLVMLLVDAFLYA--
LVTWYIEAVFPGEYGVPKPWN-FFL------VPNT-FFLLPPFL---P--HL--------
--------------T-LIKH-IH-------------------------------------
------------------S-VNIKAY

PF00005 // ENSGT00760000118965_2_Domain_1 (807, 913)

IHGYDISQHMAQIRNSLGLCPQQNLLFDHLAVSE
HLYFYCRVKGIPQKM-YLEEINNVLSAFNLMEKRDAFSKSLSGGMKRKLAIIVALIGGSK
---V-VILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1187)

SGMDPASRRTIWDLLQAYKQDRTILLTTHYMDEADVLGDRIAIMVQGT
LQCCGSSVFLKRL-YGVGYHIVMVKEPHCDIDEISK---LIHYYASTATLK---TNVGNE
LSFILPQEYTHRFE---A-LFTVLEENQENLGISSFGVSITTMEEVFL----SHMEDSKS
DSQAT--QSAS--VRS-KE---NKNKDVPS-S------------------MRGD------
--FPVQSEDPTIVFNTRCSLYYQ-QFRAMFIKRLLYNWRNWRVLL-

PF12698 // ENSGT00760000118965_2_Domain_2 (1187, 1718)

VQILGLVISTLFLL
KSHDLK-------YEDEKIRQMNLDEYGQTIV---PFSISGKSS-------LMTSLLIHL
ENMLKPGSHKLKE-EQ-----GDLLKYL-----EGNEECIHLCIIALSIKVVANGTKLTV
LFNNDAYHSQ-----------------------------SLSLAVLDNILFMSLSGADAS
IMVSKNLSHAPRIRKV----LGM-----SAEGKVVALKIQLGMALLV---------SG--
FCLLTVTERTTKAKHMQFLSGVSVLVYWLSALLFDLMNETLASLLSLSPLFQ--------
VVFKYCKIDIYITDYHILE-TMLILTLFGWSAIPLTYLMSFLFSKSTSAY------VKII
IFNYVSG--------IFSILIDT--LLV---SITLSNTTKTFLLNT-LFFPTYNLGKCVG
DYTV-------------IYQRKI-QCTQQKN-VPKYLN----CSKE--NTKQNIYSLKEH
MIGKY--LIAMG---------------ITGLVSLLFI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENTF-WKLRMLTHQHIYFG-
VCKKYKTD---KISKE--LSGESQDKDV-----ENERRKILYQPE---KFLNSPVLIKEL
TKIYFKH--PLILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1987)

VKNISFAVQERE-CFGLLGFNGAGKTTTFQILVILYSLDGLGIFIN
I----INQLKVRS-KIGYYPQFDALLEYMTGREIMIMYARM-WGVSEHQIQPYVNKHLNS
LDLE-PHANFLISTY---SGGNKRRLSTAIAIM---------GK----------------
ARCLLWDTVIKIHESGKAIII--MSHSME----ECEALCT-----RLSIMVKGKLTCLGS
PQYLKNKFGNIYILKVKVKS-------E------EALHDFKNFITLT----F--------
-P-GSDL-----KQEKQRILNYYIPRKDNSWGK--MFGILETAKEQFNLEDYSISQITLD
QVFLALANQD--------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MEEVFLW--VSKFIDSNM
DLQHI--NRLTSRNKA-LEKNN-IHLDGSDIF----------------H-----------
-------ENFN-Y-NNAFKLGFQ-QFYAMLVKKFSFTWCHWKMML-VQIIALLICITFTI
KAFKISLES---S--KTPFLQLKLNVYGETTV---PFFISKNTR-------LHPNLSGYV
SDAIKAEEQLPME-IS-----YPMDDFLINQATKDCAIFDENFLVAISFQDHKDKTTVTA
LFNNHAYHAA-----------------------------PMALAMVDNILYKLFFDSKAS
ITTTNSPQPPPKTDAAIER-LFQ-----GPKGHFLAITLMFGISFLV---------SA--
FAILPISERVIKSKHIQFICGLSKTNYWLSSLLWDLLFFLFC-----SLLIL--------
LLLKILDEKAYIQKNHSQA-TLMMLMLFAWANIPLIYLMSFFFSGIASGC------AKLI
IINIVLG--------ILPF--TF-NSIIKEMDQSLKLFS-QKTDIVFQLIPNYSLAMAFS
SLYY-------------NYEFNR-FCRSLKIGMKACQKI-----YQNYIPQENIYAWESL
GIGKY--LTSMA---------------VCGFVYLGLLFCIDTDFLWKMKIY-FSK-----
MFEKR---KLSQQPEET--PYISRDLDV-----EEEKMKIRNFLPELL--PKIPLIALEI
TKVYGHKKKKSVLAVDKVSLAIKKGE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKILTGDITITSGDAFIN
GKSISSKRTEIKK-QIGYCPQFDALLGHMTGRQLLIMYARI-WGIPEQQIQSYVAEIIFD
LLLE-TQADRLVKDY---SGGNKRKLSAGIALL---------GKPKIIFLDEPSTGMDPV
ARRLLWNQVTRAREAGKAIII--TSHSME----ECEALCT-----RLAIMVNGRFKCLGS
PQHLKSKYGSGYTLLAKIKS-------TTPKERNLAIQEFKIFVQTK----F--------
-P-GSRL-----KDEHQGMVHYHLPKQNLKWSK--VFGILENAKNEYKLDDYSISQVSLE
QIFLSFAHLQVSLYDL--------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLVLLLWKNYTL---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELLLPLLFSGILIWLRLTIQSENVP--------
----------------------NATVYPG--QSIQELPLFFSFPP---LG--GTWELAYV
PSH--SAAAKTITESVRRAL-------VINMRVHGFPTEK-------DFEDYIRYDNH-S
SNVLAAVVFENASNHSKEPLPLTVKYHLRFSHTRRNYMWTQTGNFFLKETEGWHTTSLFP
LF-PSPGPREPASP--DGGEPGYIHEGFLAVQHAVDRAIMQYHANTSAHQLFQKLT-VTA
KRFPFPPFISDPFLVAIQYQLPLLLMLSFTYTSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLMFFLFLLIAVSFM
TLLFCVKVK-KD----VAVLSRSDPSLV----------------------------LVFL
LCFAISSISFSFMVSTFFSKA---NMAAAVGGFLYFFTYIPYFFVAPHYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GTGIQWQNLLSPVNVDDDFCFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFL------LPSY-WCGNPRMVVRKEE-EDSDPEKAFR
SEYFEAEPEDLVAGI-KIKH-LSKVF-QVGNKEKAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLSLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLCFYAQLKGLSRQK-CPEEVKQMLHILSLEDKRNSLCRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQQQKNDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPKAISQ---LVYHHIPNATLE---SSAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGVM-DPTDGIGTL-
----IEEEHAVVQLNTGLALHCQ-QFWAMFLKKATYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQILVPLTCVTLAL
LAINYSSEV-----FDDPILKLSLSEYGRTIV---PFSVPGTSQ-------LDQQLSEHL
RDMLQAAGQEPRE-VL-----GDLEEFLVFRASVEGGGFNERCLVAVSFRDEVERTVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPQAS
IEVSNYPQPRSALQAAKDQ-FSE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERTVQAKHVQFVSGMHVATFWLSALLWDLISFLIP-----ILLLL--------
VVFRAFDVRAFIQDGHAAD-MLLLLMLYGWAIVPLMYLLSFFFSGASTAY------TRLT
IFNILSG--------IATFLM---VTIMRIPALKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSDVATH-------YCKKYNIEYQENFYAWSMP
GVGRF--VTSMA---------------TSGCVYLTLL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLWRLRTFVCAF-----
-WRRW---M--LAELHSRTSVVPEDLDV-----AQERNRVLTPGLDSL--LDTPLIIKEL
SKVYEQQ--TPLIAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GHSISSDIGKVRQ-RMGYCPQFDALLDHMTGREMLVMYARL-RGIPERLIGACVENTLRG
LLLE-PHANKLVRSY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVQS-------EGQQ---EALKKFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHNLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLSFAHLQPPTAEEGR------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MASWE
SRKLLLLLWKNFTL---KRRKFGTLVSEIVLVLLLSIVLLTTRHLLS-IKKI--------
----------------------EALYFPD--QPISTVPSFFRASV--TSF--YPWELAYV
PSN--IMVVENIVKNVKNDL-------NLHMKVIGFPSES-------DF

PF12698 // ENSGT00760000118965_2_Domain_0 (230, 665)

EDYARSTVN-S
RNILAAIVFGHNFANSSDPLPKKVKYYLRFSDIKKNIN-S----GAYYQGDTWLTKFLFH
SL-RLVGPRNPYEA--DGGSPGYITEGFLAVQHALDKAIMLHHGGADAAALFNDIS-LFI
QRFPYPAYYHDYFYLFATTFIPLTVACTFFFNHYVLVWSIVWEKENRLK-----------
----------------------------EYQLMIGLRNWMFWVAYFFTFLCLYFINIIVM
CMVLFVKIE-P-----APIFQYNDPTLV----------------------------FIFL
LFYAISSIFFSFMVSTLFNKV---SLAMSLGSFLFFLTYFPAVAMHQSFERMPSKQKLIW
SFDFNVGMAFGFRFLVNTDAK-KTGMKWSNIFLSTDS-DSFLFAYVLGMLLADAFIYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YIEAVFPGEYGVPKPWN-FFL------MHSY-WFGEPPQQ--KL--EITQFYERVE
SKYFEAEPTDLTAGI-QIKH-LHKVF-QKNNTTKVAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSLNLYE---GQVTVLLGH-N
GAGKST--TLSILSGLYPP-TSGEAYVHGEDISQHMDQVRNSLGLCPQQNLLFDHLTVSE
HLYFYCRIKGVPQKM-YLEETNNMLSAFNLMEKCDAFSKSLSGGMKRKLAIIIALIGGSK
---V-AILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1302)

SGMDPASRRSTWDILQTYKQNRTILLTTHYMDEADVLGDRIAIMVRGT
LRCCGSSVFLKRL-YGVGSHLVMVKEPYCDIAEISK---LIHSYVPTATLE---TNVGNE
LSFILPKEYTHRFE---A-LFTALEENQENLGISSFGVSITTMEEVFLK--VSNLEDSKT
DIEAT--QSPS--VGS-KG---NKNGDVES-S------------------GRVG------
--FPTQSEDQNIVFNTGCSLYLQ-QFRAMFMKRLMYNWRNWRGIL-VQILGLIISTFLLL
KSHEFR-------YK--KIRQMNLDEYGQTIV---PFSIWGKSN-------LTSSLLTHL
ENMLKPGNHQLKE-VQ-----GDLLKYL-----EGNDECVH

PF12698 // ENSGT00760000118965_2_Domain_2 (1302, 1718)

LCVIALSIKVVANRVNLTV
LFNNEAYHSP-----------------------------SLSLTVLDNILFMSLSGSDAS
ITVFNKPQPSPQRKEW----PG------STDGKIVAFKIQLGMALLV---------SG--
FCILTVTERHNKTKHMQFLSGVSILVYWLSALVFDLIIFFIS-----CCFLL--------
VMFKYCKFDIYVTDYHILD-TMLILTLFGWSAIPLTYLLSFLFSKSNSAY------INLL
VFCYLSG--------TLSLLMDT--IIEARISTIMSNSTQTFLLNALLLFPMYNLGKCIS
EYTV-------------IYRKKM-LCIQQKN-ALKYLN----CSNK--HTKKNIYSLKKP
MLGKY--LIAMS---------------IAGFVFLLLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFWENIS-WKVKMFIHQHIYFG-
ACKKYKPD---IISKE--LSGTSEDNDV-----ENERREILYQPE---KFLNCPVLIKEL
TKIYFKS--PLILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQERA-CFGLLGFNGAGKTTTFQILTGENIPTAGDVFID
GISLTKNIVKVRS-KIGYCPQFDALLEYMTGWEIMIMYARI-WGISEHQIQPYVKKYLNS
LDLE-SHANSLISTY---SEGNKRRLSTAIATM---------GKPSVIFLDEPSTGMDPR
ARRLLWDTVIKIRESGKAIII--TSHSME----ECEALCT-----RLSIMVRGRLTCLGS
PQYLKNKFGNIYILKAKVKS-------G------ETLDEFKNFITLT----F--------
-P-GSEL-----QQENQGILNYCIPRKNNSWGK--VFGILEKAKEQYNLEDYSISQITLD
QVFLSFADQDRK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

----------------------------------------------MKDMSPPPAGRMAV
FQRLKLLLWKNFIL---KKRKTVVTVLEILMPFLFSAIILYLRFNSV-PRRR--------
----------------------PASNYSA--FDVNSLPELFFNYP---QK--SRLQLAYI
PSQ--SEAVKAVTERVEQDF-------DVELEVLGFSSVP-------VFENYIIKDHK-A
FYILTGIVFHHRFNDSNDPLPLEVQYSLRFSYIQRNFLPLRHLFILQNDPEGWCTSFLYP
PN-PLQEPRMYKQA--DGGSPGYNREGFLAIQHAVDKAVMWHHAHNTAADMFGSLS-VLL
KRFPYGPFIQDRFFLVLQNEFPLLLMLSFICVELVIINSISLEKEKKLK-----------
----------------------------EYMCMMGLDNWLHWVAWFIMFFISVCIAVFVM
TILFCIEVN-G-----VAVFTSSDPILI----------------------------FVFL
MCFAIATIFFAFMVSTFFQRA---HVGTAVGGIFFFLTYLPYLYLTFNYQQRSHLQKILF
CLLSNVAMALGVRFISVLEAE-GLGVQWKDVG---SVRGEFNFTHVLLMLLLDSSLYC--
LVAWYVEAVFPGKFGTPKPWY-FFA------MPSY-WRGKPAPVTQTR-LAVGVPEKSVT
GKVLQEEPTDLMKGI-EIQQ-LYKVF-YKGRSEHIAVKGLTVNLYR---GQITVLLGH-N
GAGKTM--TCW

PF00005 // ENSGT00760000118965_2_Domain_1 (792, 913)

MLTGLIPC-SGGKAYINGYEISQDMAQIRKSMGWCPQHDILFDNLTVAE
HLSFYAQLKGLSPHK-CPEEVKQMLHVLSLEDKRDSRCRFLSGGMKRKLSIGIALIAGSK
---V-LILDEPTSGMDAISRRAVWDLLQQQKSDRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSPLFLKQK-YGAGYYITLLKTPRCNTEALSH---LMYHHIPNAVLE---SSAGEE
VIFILPRESVHRFE---S-LFNDLELKQAELGIASFGASVTTMEDVFIR--VCTLADSSV
NLPGS--KRSSLRPHP-LVS---------RVPVDR-------IK--HIHSRI--------
--YSIH-SGLPIRLNTGFRLLCQ-QFLAMLLKKAMHSWRGWMLMLSMQVLVPLLVIVLSL
FLFSFKERS---M--ASVPLALTLKAYGRTVV---PFSVPQNPR-------LDPQLSERF
ADMLVAQGQVPLE-VP-----GSLETFLLKKAKEEPENFNKFYLVAASFKDDGNQTIVTA
LFNNQAYHSP-----------------------------ALALSLVDNFLFKLLSGNRAS
IITSNHPQPQSETEISESV-LYQ-----GPKGHYLVVNLLFGIAFLS---------SS--
FSILTVRERRIKAKHIQFVSGVYLWAYWLSALLWDLISFLVP-----TLLMV--------
VVFLYYNEEVFTHRGNILA-LVLMLILYGWAIIPLIYIISFSFESASHAC------VKLV
VMLTFLS--------IGPI--ML-VTVTAEQDLGYEAIS-ENLDHAFLALPGHCLGMAFC
NLYY-------------NFELQR-FCSVKNLSQTECNEA-----SEKYVVQKNIYAWESL
GIGKY--LTALA---------------ISGPVYIILLFLIETSAFWTLKAR-LSD-FCG-
--KPS---LA--V-PLNVPS-APEDQDV-----AKEAETIKMHLEKLC--KKNPLVVKEV
SKVY-EN-KVPVVAVNKVSFTVQAKE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TSIFKMLAGEKPITSGEAFVR
GISISSDLERVRK-WIGYCPQFDALLNFMTGRETLVMYSRI-RGIPECHISTCVDQILED
LVLY-MDADKLVKTY---SGGNKRKLSTGIALL---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAVVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLQAKVRS-------RGQQ---EALRDFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHNLSWAK--VFGLLEAAKNEYQLDDYSVSQVSLE
DIFLSVAYPMYRTQGQDQRGQTPPPPRSS----------------------------APP
PAPALL------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------FIIPFLFKA---HVAASAGNLLFFASFFPFNFIAENYGATILTNKVAA
CVSSNIALALGINLLLKMEIK-QTGIKWNNFWTPATLEDNLVFGYLIGMLLFDAFLYG--
LATWYIDNVFPGPYGVPQPWY-FFL------MHSY-WCGKPRIREE-K--EDIKDNSSIQ
SNYFEEEPTSLVAGI-QIKH-LHKIS--QEHRKRKLVTDLSLNVYE---GQITILLGH-N
GSGKTA--

PF00005 // ENSGT00760000118965_2_Domain_1 (789, 912)

TLSILTGCYPA-TSGEVFISGYDVSKDTSEIRKTLGYCPQYDSLFDNLTLSE
HLFFYSVIKGIPQKM-HPMETDHLLTVFNLIEKRDTFSQSLSAGAKRKLSIIIALLGGSK
---V-VILDEPSSFMDPVSRRVTWDLLQQYKQNRTILMTTHSMDEADILGDRIAIMVKGN
MQCCGSSVFLKQIFGRAGYHIVMEREPNCNVEKISA---IIHSHVPDAILE---KDITTR
LSFILPKEYTQRFE---A-LFDDLGRKQKELGIANFGASISTMDEVFFK--LYKLEDNFI
NLQQI--QRGGQGQEG---QAGGTN----VKS------------------GRLR------
--LSPEKELSMIKFNTGLPLYYQ-QFRSMFMKRALFSWRNWKLTL-LQIIVILVITTYIL
RTLKVP-------KNNEPSREMELSHYGQTIV---PYSVSGNSD-------LVLTLIKNL
KIFLKSKNQELQE-IQ-----GSVTDYI-----LGSRKCHDFCIIALSIEVEKDKTVITI
LFNNEAYHSA-----------------------------ATSLAVLDNILFMSLSGPNAS
ITVSNKPQPL--PPYGSKI---A-----PAHGLEVALSLAFTLAVVV---------GG--
FCLQTAIERISKAKHIQFVSGVYLLVYWLSALLYDLIYFFIF-----CCLLL--------
GVFFYCGVEAFVVDYHFLD-TILIFMVYGWCTIPFVYLGSFLFSSSTAAY------IKLT
LFNYFSA--------VFSIIIQAIITYYG---EQFPSSPRIFVEHLLMMLPNYNFAMIVS
IFFD-------------DFQLKK-LCSKQF--RSIYLN----CSKQ--FIQNNIYSFGEH
GIAKF--LIALA---------------TMGLFFLLLLLCLETTS-WSLKNFVFRNIIYN-
FYKKYTKC---KINRK--KKKEYEEEDI-----KNERKKALELHQ---TLENTPVLLKEL
IKIYFKC--PVVKAVRNISLVVNNSE-CFGLLGLNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTLKMLAGEETITSGVVLIN
GISVTENIRKVRS-RIGYCPQSDSLMTYMTGRELLSMYARL-QGVPEPSIHNYVEAFLHL
VYLK-PHADEFVYTY---GGKRKRRLNIAIALM---------GNSSVVFLDEPSAGMDPV
GKHLLWEAVSWICKTGKVIII--ASHSME----ECEAFCT-----RLAIMVKGKFMCLGS
PQELKNKFGNIYTLTAKIKI-------NTEE---DKIEEFKEFIKAV----F--------
-P-GSII-----NQEYQGILGYYIPSQEICWGK--VFNVLEEAKVMFNLEDYSVHQISLE
QIFLTFANTDKK------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MEV
FKKLKLLLWKNFIL---KKRKTLITLLEILMPLIFSAIILYLRFNSM-PKLV--------
----------------------SSTTYEE--VDISLLPVYFHHYP---LK--SKFQLVYI
PSK--SETLKAVTEMVEQTF-------AVDFEVLGFPSVP-------LFENYIIKDPK-S
FYILVGIVFDHSFNSSNEPLPLVVKYDLRFSYVQRNYVPSLNHLFFPDEVEGWRTAFLYP
PN-MNPEPREFAYA--DGGSPGYNKEGFLAIQHAVDKAIMWHHAPSATLNMFKNLN-VLL
QRFPFGPHVQDPFLVILQNEF

PF12698 // ENSGT00760000118965_2_Domain_0 (382, 664)

PLLLMLNFICIELIVINSILLEKEKKLK-----------
----------------------------EYMCMMGLESWLHWVAWFITFFISVLIAVSVM
TILFCTKIN-S-----VAVFRNSNPSLI----------------------------FIFL
MCFATATIFFAFMMSTFFQRA---HVGTVIGGIVFFLTYLPYLYITFSYHQRTYFQKIAF
CLFSNVAMAIGVRFISLFEAK-GIGIQWSNIG---SVQGDFSFSQVLLLLLLDSFLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVDSLFSGKFGIPKFWY-FLA-------------KKPVPVVLPL-LDIGDPEKHSR
REFMQDGPTDQMKEI-EIKH-LYKVF-YRGRSKRIAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSMNLYQ---GQITVLLGH-N
GAGKTT--ICSILTGLISP-SKGQAYVNGYEVSKDMIQIRKSLGWCPQHDILFDNFTVTD
HLFFYGQLKGLSHQN-CREEIEEMLRLLSLKHKWNSRSKFLSCGMKRKLSLGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1184)

SGMDSTSRRAIWDILQQQKSGHTILLTTHFMDEADLLGDRIAILAKGE
LQCCGSPPFLKEK-YGAGYYMTLIKTPLCDTMKLSS---VVYHHIPNAVLE---SSNGEE
MIFILPKKNVPSFE---A-LFTDLEQRQTELGISTLGVSVTTLEEVFIR--VYKLADTTT
NILSE--KRPSIHPHP-R-------IH--RVPVDR-------IK--CLHSRI--------
--FSTQ-TDLPIILNTGLCLLCQ-QFFAMLLKKVAYSWRNWML

PF12698 // ENSGT00760000118965_2_Domain_2 (1184, 1718)

MLCVQILLPLVVTVLSL
TFFDFKLKK---M--ENVPLELTLKTYGQTIV---PFFVSKNSH-------LDPQLSDNF
IKMLVAAGQIPLH-VQ-----GPVEDFLLKKAKEAPEDFDKLYVVAASFEDVNNHTTVKA
LFNNQAYHSP-----------------------------SIALALVDNFLFKLLSGTNAS
ITTTNYPQPQTAEELSESI-LYQ-----GPKGHYLVINFLFGIAFLS---------SS--
FCILTVTEKNIKSKHIQFVSGVSAVAFWLSALLWDLISFLVP-----TLLLV--------
LVFLWYKEEAFAHHENSPA-VVLIMILYGWAVIPFIYTVSFSFKTPGNAC------VKLV
VMLTFLS--------ISPN--VL-VTVTSDKDLGYEELS-NSLDHMFLILPGHCLGMAFS
NLYY-------------NFELKK-FCSAKNLSDIACNDV-----SEGYVVQKDIYAWESL
GIGKY--LTALA---------------ILGPVYIILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIEANTFCILKSK-LSG-FSG-
--KEK---MG--I-FLD--EMEDE--DV-----LEEAEAIKFYFETLI--KKNPLIVKEV
SKVY-NM-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFTVEEKE-CFGLLGLNGAGKTSIFNMVTGEQPITSGDVFVK
GFNIKSDLVKVRQ-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPERHIKTCIDQIIED
LLMH-VYADKLVKTY---SDGNKRMLSTAIALI---------GEPAVILLDEPSTGMDPV
AQRLLWDTVARARESGKSIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGTGYSLQARVQR-------ELEQ---EALKKFKAFVEMT----F--------
-P-GSNL-----EDEHQGMVQYYLPGYSLSWAK--VFGIMEQAKKDYMLEDYSINQVSLE
DIFLSLTSPMSSTKGKFQQGQAVVASPLSSF-------HLLSP-LHSSSQPSIPPPSPPP
SEPVLL------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MEV
FKKLKLLLWKNFIL---KKRKTLITLLEILMPLIFSAIILYLRFNSM-PKLV--------
----------------------SSTTYEE--VDISLLPVYFHHYP---LK--SKFQLVYI
PSK--SETLKAVTEMVEQTF-------AVDFEVLGFPSVP-------LFENYIIKDPK-S
FYILVGIVFDHSFNSSNEPLPLVVKYDLRFSYVQRNYVPSLNHLFFPDEVEGWRTAFLYP
PN-MNPEPREFAYA--DGGSPGYNKEGFLAIQHAVDKAIMWHHAPSATLNMFKNLN-VLL
QRFPFGPHVQDPFLVILQNEF

PF12698 // ENSGT00760000118965_2_Domain_0 (382, 664)

PLLLMLNFICIELIVINSILLEKEKKLK-----------
----------------------------EYMCMMGLESWLHWVAWFITFFISVLIAVSVM
TILFCTKIN-S-----VAVFRNSNPSLI----------------------------FIFL
MCFATATIFFAFMMSTFFQRA---HVGTVIGGIVFFLTYLPYLYITFSYHQRTYFQKIAF
CLFSNVAMAIGVRFISLFEAK-GIGIQWSNIG---SVQGDFSFSQVLLLLLLDSFLYC--
LIA

ENSGT00760000118965_2_Linker_0_1 (664, 758)

FLVDSLFSGKFGIPKFWY-FLA-------------KKPVPVVLPL-LDIGDPEKHSR
REFMQDGPTDQMKEI-EIKH-LYKVF-YRGRSKRIAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSMNLYQ---GQITVLLGH-N
GAGKTT--ICSILTGLISP-SKGQAYVNGYEVSKDMIQIRKSLGWCPQHDILFDNFTVTD
HLFFYGQLKGLSHQN-CREEIEEMLRLLSLKHKWNSRSKFLSCGMKRKLSLGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1184)

SGMDSTSRRAIWDILQQQKSGHTILLTTHFMDEADLLGDRIAILAKGE
LQCCGSPPFLKEK-YGAGYYMTLIKTPLCDTMKLSS---VVYHHIPNAVLE---SSNGEE
MIFILPKKNVPSFE---A-LFTDLEQRQTELGISTLGVSVTTLEEVFIR--VYKLADTTT
NILSE--KRPSIHPHP-R-------IH--RVPVDR-------IK--CLHSRI--------
--FSTQ-TDLPIILNTGLCLLCQ-QFFAMLLKKVAYSWRNWML

PF12698 // ENSGT00760000118965_2_Domain_2 (1184, 1718)

MLCVQILLPLVVTVLSL
TFFDFKLKK---M--ENVPLELTLKTYGQTIV---PFFVSKNSH-------LDPQLSDNF
IKMLVAAGQIPLH-VQ-----GPVEDFLLKKAKEAPEDFDKLYVVAASFEDVNNHTTVKA
LFNNQAYHSP-----------------------------SIALALVDNFLFKLLSGTNAS
ITTTNYPQPQTAEELSESI-LYQ-----GPKGHYLVINFLFGIAFLS---------SS--
FCILTVTEKNIKSKHIQFVSGVSAVAFWLSALLWDLISFLVP-----TLLLV--------
LVFLWYKEEAFAHHENSPA-VVLIMILYGWAVIPFIYTVSFSFKTPGNAC------VKLV
VMLTFLS--------ISPN--VL-VTVTSDKDLGYEELS-NSLDHMFLILPGHCLGMAFS
NLYY-------------NFELKK-FCSAKNLSDIACNDV-----SEGYVVQKDIYAWESL
GIGKY--LTALA---------------ILGPVYIILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIEANTFCILKSK-LSG-FSG-
--KEK---MG--I-FLD--EMEDE--DV-----LEEAEAIKFYFETLI--KKNPLIVKEV
SKVY-NM-KVPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFTVEEKE-CFGLLGLNGAGKTSIFNMVTGEQPITSGDVFVK
GFNIKSDLVKVRQ-WIGYCPEFDALLNFMTGREMLVMYARI-RGIPERHIKTCIDQIIED
LLMH-VYADKLVKTY---SDGNKRMLSTAIALI---------GEPAVILLDEPSTGMDPV
AQRLLWDTVARARESGKSIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGTGYSLQARVQR-------ELEQ---EALKKFKAFVEMT----F--------
-P-GSNL-----EDEHQGMVQYYLPGYSLSWAK--VFGIMEQAKKDYMLEDYSINQVSLE
DIFLSLTSPMSSTKGKFQQGQAVVASPLSSF-------HLLSP-LHSSSQPSIPPPSPPP
SEPVLL------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MA

PF12698 // ENSGT00760000118965_2_Domain_2 (1425, 1717)

LLI---------SG--
FCLLTVTERTTKAKHIQFVSGVSVIVYWLSALLCDFIIFFAS-----CCLVM--------
GVIKYRKFDIYVTDYHILE-TMLIFTLYGWSAIPFVYLISFVFAGSTSAY------IKLL
LLSYFSG--------TFGFLIG--EIIENKKLTNISNTTRTVVRNSLLFLPNYNLAKCIS
QYTA-------------IYEMKI-LCTTLKK-HPIYLN----CSKE--NTEKNIYSLEEP
MIGKY--LIDMS---------------TAGFIFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1815)

IFFWETTS-WRLRTFLNQYIYFG-
IYKRYRKD---IVSKE--LSGQSEDEDV-----QNERKRILEQPQ---ELLDSIVLIKEL
IKIYFKC--PAILA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFQILTGEASPTSGDVLID
GFSITKDILQVRS-RIGYCPQFDALLEYMTAQEIMIMYARI-WGVSEPQIELYVNKWLNS
LELE-SHADRLINTY---SEGNKRRLSTAIALM---------GRSSVIFLDEPSTGMDPV
ARRLLWNTVTKTRESGKAIVI--TSHSME----ECDALCT-----SLAIMVQGKFMCLGS
PQHLKNKFGNIYILKVKVKT-------K------DELEDFKRFVTTT----F--------
-P-GSVL-----KHENQGILNYYIPSKDNRWGK--VFGILEQAKEQFDLEDYSVSQITLE
QVFLTFANPEKVS--SDDENE-----VP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRHLALLLWKNYTL---KKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DSWELAFI
PSH--SDAAKTITETVRREL-------VINMRVRGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHTFNHSKDTLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMQYHAEAATHQLFQKLT-VMA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYSSLTITRAIVQEKERKL------------
---------------------------KEYMRMMGLSNWLHWSAWFLLFFLFLLITVSFM
TLLFCIKVK-KD----VAVLSHSEPSLV----------------------------LAFL
VCFAISSISFSFMVSTFFNKA---NMAAAVGGFLYFLTYVPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLMGKFEAK-GTGIQWQDLLSPVSVDDDFCFGHVLGMLLLDSVLYG--
LATWYVEAVFPGQFGVPQPWY-FFV------MPSY-WCGNPRTVIGKEE-EDSDPEKVLG
TEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDKAAVKDLNLNLYE---GQITVLLGH-N
GAGK

PF00005 // ENSGT00760000118965_2_Domain_1 (785, 913)

TT--TLSMLTGLFPP-TSGQAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVVE
HLYFYAQLKGLSRQK-CPEEVKKMLHILGLEDKWASRSRFLSGGMKRKLSIGIALIAGSK
---V-LILDEPTSGMDAISRRAIWDLLQQQKSDRTILLTTHFMEEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEGISQ---LVYHHVPNATLE---SNAGAE
LSFILPKESTHRFE---S-LFAKLEKKQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DMQAI--QLPPLQYQH-ERRASDWAVDS---------------NLCGAM-DPTDGIGAL-
----IEEQCATVKLNTGLALHCQ-QFWAMFLKKATYSWREWKMVA-AQVLVPLTCVTLAL
LAVNYSSEI-----FDDPILKLILGAYGRTVV---PFSVPGTSR-------LGQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGEQMVVTA
LFNNQAYHSP-----------------------------ATALAIVDNLLFKLLCGPLAS
IMVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAAQAKHVQFVSGVRVATFWLSALLWDLLSFLVP-----SLLLL--------
AVFKAFDVHAFTRDSHPAD-VLLLLLLYGWAIIPLMYLSTFFFSGAATAY------TRLT
IFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVAAH-------YCKKYNIKYQENFYAWRAP
GVGRF--VASMA---------------ASGCAYLILLFLIETNLLWRLRTFICTF-----
-RRRQ---M--LTELCTRTSVLPEDQDV-----ADERSRVLAPSLDAL--LNTPLVIKEL
SKVYEQR--VPLLAVDKVSLTVQKGE-CFGLLGFNGAGK

PF00005 // ENSGT00760000118965_2_Domain_3 (1840, 1974)

TTTFKMLTGEDSITSGDAFIG
GHSISSDIGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPECHIGACVENTLRG
LLLE-PHANKLVKTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRN-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGYDLSWAK--VFGILEKAKEKYGVDDYSVSQISLE
QVFLGFAHLQPPTVEEGQ------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAA
FKKLKLLLWKNFTL---KKWKTLVTLLEILMPLLFSAIILYLRFSSV-PQKR--------
----------------------HSTVYQA--IDISSLPEYFHYFP---LK--SRFQLVYI
PSK--SESLKAITEMVERAF-------DVDFEVLGFPSVP-------FFEKYIIKDPK-A
FYILVGIVFEHNFNDSNEPLPLRIKYDLRFSYIQRNFEPSLKHLFILEDIEGWCTALLYP
PN-LSQGPREFAYS--NGGNPGYNKEGFLAIQHAVDKAIMWHHAPNATFNMFKNLH-VLL
QRFPYGPHICDSFFMILQNE

PF12698 // ENSGT00760000118965_2_Domain_0 (381, 616)

FPLLLMLSFICVELITINSVALEKEKKLK-----------
----------------------------EYMCMMGLESWLHWVAWFITFFVSVLIAVSVM
TVLFCTKVK-N-----VAVFKNSDPILI----------------------------FVFL
MCFAIATIFFAFMISTFFQR------GTVIGGIIFFFTYLPYLYLTFSYHQRTHVQKIAS
CLFSNVAMAIGVQFI

ENSGT00760000118965_2_Linker_0_1 (616, 758)

SQFEAE-GTGIQWRNIG---SIRGEFSFIQ---------------
--------------------------------CFS-WLKKPAPVILPL-LDIRNPDKLSR
NEFMQEEPTDLMKAI-EIQH-LYKVF-YRGSKEHIAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLSMNLYK---GKITV-LGH-N
GAGKTT--TCFMLTGLIAP-SKGQAYINGYEISTDMVQIRKSLGWCPQHDILFDNFTVAD
HLSFCAQLKGLSLPK-CHEEIKQILSILCLEDKWNSKSKYLSRGMKRKLSIGIALIAGSK
---I-LVLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1251)

SGLDSTSRRVIWDLLQQQKSDHTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKKK-YGTGYYMTLIKTPLYDTEKVSD---LIYQHIPNAVLE---SSIGEE
LIFILPKKTMPRFE---G-LFTDLEKRQEELGIYTLGASVTTMEEVFIQ--VCKLADSST
HILTE--KRPSIQPHP-Q-------IH--RVPVDR-------IR--YLHSRI--------
--FSKQ-TDLTIKLNMGFSLLCQ-QFYAMFLKKVVYSQRNWKLMLPVQVLLPL-------
-----------------------------TIV---PFFVSDKSH------

PF12698 // ENSGT00760000118965_2_Domain_2 (1251, 1718)

-LDPQLSNHF
ENMLVASGQIPLK-IQ-----GSVEEFILKKAKEDPEDFDRRYLVAVSFEDINNHTVVKA
LFNNQAYHSP-----------------------------GLALALVDNLLFKLLSGFNAS
ITTINYPQPQTSEEVSESI-LYQ-----GPKGHYLVINFLFGITFLS---------SS--
FSILTVRERHIKSKHVQFASGVNMAAFWFSALLWDLLSFLVP-----TLLLV--------
LVFLWYDEEAFTHRDSILA-VVSMLMLYWWAVIPLIYMVSFSFESPGTAC------VKLT
IMLTFLS--------ICPI--VL-ISVTGERDLGYPELS-HSLDHIFLILPGHCLGMAFS
NLYY-------------NFELNK-FCTAKNLSDADCNDV-----LEGYVVQKKIYAWESL
GIGKY--LAALA---------------ILGPVYIILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FFIETDMFWLLKSR-IIN-FYR-
--KQN---LE--M-FQDVTESEDE--DV-----IEEAEIIKVNLESIR--KQNPLVVKEV
SKIY-ED-KV--LAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

NKVSFTVKAQE-CFGLLGLNGAGKSSIFKMLTREKPITSGDVFVE
GLNIKTNLRQVRQ-WIGYCPEFDALLNFMTGRELLAMYARI-RGIPECHISTCVNQILED
LSLC-TYADKLVKTY---SGGKKRKLSTGIALI---------GEPAVIFLDEPFTGMDPV
ARHLLWVTVGRVRESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
LQHLKSKFSSSYSLQAKVQR-------QWQH---EVLEEFKAFVDLT----F--------
-P-GSNL-----EDEHQGLIQYHLPGHNLSWAK--VFGIMEQAKKDYKLEDYSINQS---
------------------------TNPLPPS---QSQPFLLPP-S--------PPPFLPP
SEPVLL------------------------------------------------------
---------------------------------------------

-------------------------------------------------------MDLLT
FNQFAVLLWKNFTL---KRRQFFNLMLEILAALVFPLMLLLFRSVVT-ITAI--------
----------------------GPYNFTS--QPISTLPSFLKNA--------EEWKLVYV
PSN--VDVLKDITENVKRNL-------NISIQVQGFSSET-------EFEKHIKHDFD-S
EKVLAAIVFDYDFKNSSDPLPLQVKYRLRFSGIERTVL--------WPDRQGWKTSLLFP
NF-PSGGPRNPSYQ--DGGSPAS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------LVASAGSFLYFASFFPFNTITENYGQITLTRKVAA
CLSPNIALALGIKLLVKLELK-QVGVKWKHLWTPANLEDKLIFKYMLGMLLFDAFFYG--
LVTWYVENVFPGQYGMPQPWY-FFL------MRSY-WFGQARI--K-R--KEMKDCRITL
TKYFEAEPTSLVAGI-RIKH-LYK-----KFGDKVAI

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 912)

NDMSLNLYK---GQITILLGQ-N
GAGKTT--VLSVLTGCYRP-TRGEVCIYGYDISKNIREIRENMGFCPQHDLLFNDLTLSE
HIFFYSVVKRIQQKI-PPLEVDNMLSTFNLLEKRDTFSESLTGGMKRKLSIIIALLGSPK
---V-VILDEP

ENSGT00760000118965_2_Linker_1_2 (912, 1239)

SSGMDPVSRRATWDVLQQFKHKRTILLTSHYMDEADILGDRIAIMVKGT
LQCCGSSIFLKKI-YGAGYHIVIEREPRCDAEKISA---VIYSRIPDAILE---NSIGTE
LSFILPKEHTHRFE---A-LFNELEEKQKELGIASFGASITTMEEVFLK--VNKLADSQT
DVRPS--QSH----QK-RRQDMEQNVSVSRSH------------------ERPV------
--FPSLNETANIKFNTGFPLYRQ-QFHSMFIKRALFNWRNWRLTL-LQISVILFVTTYLL
TTLSL--------DFDLPARELDLSQYGRTIV---PYS

PF12698 // ENSGT00760000118965_2_Domain_2 (1239, 1717)

ISGNSD-------LALNLIKNL
KIFLKLKNQELRR-VQ-----GNVKNYI-----LESKEYRDFSITAFSIKVEKNKTIVTI
LFNNEAYHSA-----------------------------ATSLAVLDNILFMSLSGLNAS
IRVSNKPQPL--PLYGSNVG--------PTNGVQVALSLAFGMALVV---------SS--
FCLQTVTERTTKAKHIQFVSGVYLLTYWLAALLWDLIYFSII-----CCFIL--------
GVFIYCRVDAFFVNYHFLD-TMMIFLLYGWSVVPLMYLGSLLFSSSPIAY------IKLT
LFNYFST--------VFSVVFHIMVQHTA---IDMHESARTFLGNALMMLPNYNFAMSIS
KFFD-------------DYMMKK-LCTTHKQFQSIYVN----CNKI--FTENSVYSFGEH
GIAKF--LISLA---------------ALGLIFLLL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFCLESTF-WSLKNFFFHKIVFA-
VYKIFRKRKKATVSTQ--VINEYVDKDV-----ENERKRVLALLP---KLKAAPVLLSEL
TKIYFKC--PVVMAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1870)

RNVSLLVQKYE-CFGLLGLNGAGKTTIFKMLTGEETLTSGVVLIK
DNNITENIRKVFL-DLI--TESVP------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTV---QKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFSFPP---PG--DTWELAYI
PSQ--SDAVRTVTEMARRTL-------VINMRARGFPSEK-------DFEDYIRYDNR-S
SNVLAAVVFEHTFNHSGEPLPLAVKYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPASP--DGGEPGYIREGFLAVQHAVDRAIMQYHANASTRRLFEKLT-VTA
KRFPYPPFISDPFLVAVQYQVPLLLVLSFTHSSLTIIRAVVQEKERKL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLLLLAAVSLV
TLLLCVTVK-KD----VAVLTHSDPSLV----------------------------LVFL
LCFAISSVSFSFMVSAFFSKV---EPTAAVGGFLFFFTYTPYFFVAPRYNRLTLRQKLLS
CLLSNVAMAMGAQLIGKFEAK-GVGVQWRDLLSPVNVDDDFSFGQVLGMLLLDSILYG--
LVTWYVEAVLPGQFGVPQPWY-FF------IMPSY-WCGHPRTVLGKEE-EDDDPEKALR
TEYFEAEPEDLVAGI-KIKH-VTKVF-RVGNKGKAAVRDLNLNLYE---

PF00005 // ENSGT00760000118965_2_Domain_1 (770, 959)

GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYINGYEISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVQRMLHVLSLEDKQDSLSRFLSGGMKRKLSIGIALIAGSK
---V-LMLDEPTSGMDAISRRAIWDLLQQHKSDRTVLLTTHFMDEADLLGDRVAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEAISR---LVQHHVPSATLE---SRAGAE
LSFILPKESTHRFE---S-LFTKLEKQQQELGIASFGASVTTMEEVFLR--VGKLVDASL
DIQAV--QLPALQYQH-ERRASDWAVDS---------------HLCGAM-DPTNGVGSL-
----IEDECTPAKLNTGLALHCQ-QFSAMFLKKAVYSVREWKMVV-AQVLVPLTCVTLAL
LAVNYSSET-----FDDPKLELTLGAYGRTVV---PFAVPGASR-------LDQQLSEHL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAVSFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKQLCGPRAS
IVVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLLSFLVP-----SLLLL--------
AVFKAFDVHAFTRDGHMAD-ALLLLMLYGWAIIPLMYLMNFLFSGAATAY------TRLT
VFNILSG--------IATFLV---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFHE-------------NFEMRK-YCTSSEVAAH-------YCRKYNIRYQQNFYAWSTP
GVGRF--VTSMA---------------ASGFAYLSLLFLIETDTLWRLKTCICAF-----
-RRKR---A--LTEVYTRSSAPPEDQDV-----VDERSRVLAPSTDSL--LDTPLVIKEL
SKVYEQR--TPLLAVDKISLAVQK

PF00005 // ENSGT00760000118965_2_Domain_3 (1825, 2033)

GE-CFGLLGFNGAGKTTTFKMLTGEETITSGDAFVG
GYSISSEIGKVRQ-RIGYCPQFDALLDHMTGRETLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALL---------GEPSVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVRS-------DGQQ---EALEEFKAFVNLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGDDLSWAK--VFGVLEKAKEKYAVDDYSVSQISLE
QVFLSFAHLQPPAEDEGP------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MVV
LRQFGLLLWKNYIL---QKRQILVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

IIEICLPLLFAAILIALRHRVHSVSHP--------
----------------------NATIYPS--LSVDDLPGFFYRRH---PG--NPWELAYV
PSN--SSAVQSIARAVERAL-------PISIRAQGFASER-------DFEDYVRRDNR-S
GSVLAAVVFKHHFSHSTDPLPLQVDYELRFKYSPRNAPRSEQTGLNPNLDRDWHTSYLFP
LF-QLPGPREAKFV--DGGTPGYIREGFLAVQHAVDRAIMQYHTNSSATSLLENIT-VVV
QRFPYPSYVNDLFVLAIQNQLPLLLMLSFTYTSLNIVRAVVHEKEKKL------------
---------------------------KEYMHMMGLSNWLHWSAWFLMFFLFLLVSVFFV
TLLFCVKVS-EQ----GAVLTSSDPTLV----------------------------FTFL
AIFSISTISFNFMVSTFFSRA---NVAAAAGGFLYFFSYIPYFFISPRYDLMSHSQKLAS
CLISNVAMAMGAQLIGMFEGK-GTGIQWRDLMKPVSVDDNFTLAQVLGMLLLDSVLYG--
LVAW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVFPGEYGVPQPWY-FFL------TPSY-WCGQPRTVIGKEKEEEEDPEKALK
SQYIEEEPADLVSGI-KIKH-LSKVF-KVGSKTKEAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

KDLTVNMYE---GQITVLLGH-N
GAGKTT--TLSMLTGLYSP-TSGQAYINGYEISQDMVLIRRSLGLCPQHDVLFDNMTVEE
HLHFYAGLKGYPASK-CPEEINHILRILNLEDKRHSLTKALSGGMKRKLSIGIALIGDSK
---V-VMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDPASRRATWDLLQQQRSNRTILLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKRK-YGAGYHMVMVKEPYCNLGEISR---LICQYVPNATME---SNAGAE
LSFILPKESTHRFE---A-LFTELELKREELGIASYGASVTTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRSNDWAMDDSS-------------SLSGMT-DMTDDSGAL-
----ITEDCSSIKLNTGFYLCCQ-QFYAMFMKRAMYSWRN

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1717)

WKMVA-AQFLVPLIFTAFAL
IVAKTFPGP-----RDSSMLRLTLEPYGQTIV---PFSVPTASG-------LPQRLAEQY
VELLDAQHQSPLE-VP-----GGLEEYLISRASEEGGAFNEHYIAAASFEGAGNHTVVTA
LFNNQAYHSP-----------------------------ATALMLADNAVFRVLMGPNAS
ITVTNYPQPRNITEKAKDQ-LME-----GQTGFAIAINLLYGMASLA---------ST--
FALLLVSERAIKAKHVQFVSGVYVVNFWLSALLWDIINFLIP-----CALML--------
VIFQAFDVQAFTQDSHLVD-VMLIFLLYGWAIIPLMYLLSFFFSVAATAY------TRLT
IFNILSG--------TATFLA---VTIMSIPELGLVDLS-RTLDKIFLTLPNYCLGQCIS
DFYQ-------------NYEFIQ-FCTSSVEAIF-------ICKAFNISYQVNYFSWESP
GIGQY--LTSLT---------------VQGFSFLFL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFLIETNLLWRLKTLVCGI-----
-CRRR---K--WVALLNSVSVLPEDRDV-----ADERKKVLESPPELLSSLSSPLVIKEL
TKVYDSR--ESLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVSKGE-CFGLLGFNGAGKTTTFKMLTGDESITSGDAFVD
GHSILANIKKVQQ-RIGYCPQFDALLDHMTGRETLSMYARL-RGIPERYIGSCVENMLRG
LLLE-PHADKLVRTY---SGGNKRKLSAGIALI---------GGPPVIFLDEPSTGMDPV
ARRLLWDAVTRTRECGKSIIF--TSHSME----ECEALCT-----RLAIMVNGQFKCLGS
PQHLKSKFGSGYTLLAKTRTD--------EE---GELQAFKAFVEKT----F--------
-P-GSVL-----KHEHQGMVHYHLTNKNLSWAQ--VFGALEKAKEKYRLEDYSVSQISLE
QVFMSFTRFQHYTEDRGK------------------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTL---QKRKVLVTVLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFTFPP---PG--DTWELAYI
PSH--SDAAKTVTETVRRAL-------VINMRVRGFPSEK-------DFEDYIRYDNR-S
SSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTRRNYMWTQTDSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAVQHAVDRAIMEYHADAATRQLF

PF12698 // ENSGT00760000118965_2_Domain_0 (353, 665)

QRLT-VTI
KRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTALTIARAVVQEKERRL------------
---------------------------KEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFM
TLLFCVKVK-PN----VAVLSRSDPSLV----------------------------LTFL
LCFAISTISFSFMVSTFFSKA---NMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCS
CLLSNVAMAMGAQLIGKFEAK-GMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVFYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YMEAVFPGQFGVPQPWY-FFI------MPSY-WCGKPRAVAGKEE-EDSDPEKALR
NEYFEAEPEDLVAGI-KIKH-LSKVF-RVGNKDRAAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLNLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAE
HLYFYAQLKGLSRQK-CPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAGSK
---V-LILDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1181)

SGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCNPEDISQ---LVHHHVPNATLE---SSAGAE
LSFILPRESTHRFE---G-LFAKLEKKQKELGIASFGASITTMEEVFLR--VGKLVDSSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------NLCGAM-DPSDGIGAL-
----IEEERTAVKLNTGLALHCQ-QFWAMFLKKAAYSWRE

PF12698 // ENSGT00760000118965_2_Domain_2 (1181, 1718)

WKMVA-AQVLVPLTCVTLAL
LAINYSSEL-----FDDPMLRLTLGEYGRTVV---PFSVPGTSQ-------LGQQLSEHL
KDALQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKLLCGPHAS
IVVSNFPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVASFWLSALLWDLISFLIP-----SLLLL--------
VVFKAFDVRAFTRDGHMAD-TLLLLLLYGWAIIPLMYLMNFFFLGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-KTLDRVFLVLPNHCLGMAVS
SFYE-------------NYETRR-YCTSSEVATH-------YCKKYNIQYQENFYAWSAP
GVGRF--VASMA---------------ASGCAYLILL

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLIETNLLQRLRGILCAL-----
-RRRR---T--LTELYTRMPVLPEDQDV-----ADERTRILAPSPDSL--LHTPLIIKEL
SKVYEQR--VPLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DRISLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEESLTSGDAFVG
GHRISSDVGKVRQ-RIGYCPQFDALLDHMTGREMLVMYARL-RGIPERHIGACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALI---------GEPAVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIVI--TSHSME----ECEALCT-----RLAIMVQGQFKCLGS
PQHLKSKFGSGYSLRAKVQS-------EGQQ---EALEEFKAFVDLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGHDLSWAK--VFGILEKAKEKYGVDDYS-------
------VSQ----ISLEQVFLS-FAHLQP----PT------A------------------
-EEGR-------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------M

PF12698 // ENSGT00760000118965_2_Domain_2 (1424, 1718)

SIFI---------SG--
FCLLTVTERVTKAKHIQFLSGVYAINFWLSALVWDFFIFFIS-----CCLLL--------
VI--------LVTDYHFLD-TLFILMLFGWSVIPFMYLISFLFSSHTSAY------IKLV
IFNYCAG--------VFDFLI---TGLL----QDKESASKSHMLNSMMLLPIHNLGMSIS
RYYD-------------FQQTKA-TCASKKN-VPIFMN----CSE-----EGNVYGLEAD
AIGRF--LIAMA---------------VTGLIFFLLI

ENSGT00760000118965_2_Linker_2_3 (1718, 1816)

FLLETTS-WTMRTFVFRSIFFG-
IYKKFNKE---RVSME--LSVESEDEDV-----QNERNRILEYPQ---ESLNSTVLIKEL
AKIYFAM--PAVFAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

RNISVAIKKEE-CFGLLGLNGAGKTTSFQILTGEEVATSGDVFIE
HLSITKNVLKVRS-KIGYCPQFDALLDYMTAREIMTMYARL-WGIPEKQINHYVNKSIQS
LNLE-PYADKFIYTY---SGGNKRRLSTAIALM---------GKPSVIFLDEPSTGMDPV
ARRLLWNTVTQTRESGKVIII--TSHSME----ECDALCT-----RLAIMVKGKFVCLGS
PQHLKNKFGNVYILKAKIKI-------DKDE---NKLKDFKDFMATT----F--------
-P-GSEL-----KHENQGILDYYVPSKDNSWGK--MFGILEEAKEEFHLEDYSISQITLE
QVFLTFANPENTEAHG--------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MALLI--------

PF12698 // ENSGT00760000118965_2_Domain_2 (1436, 1718)

-SS--
FCLQTVTERVSKAKHIQFVSGVYVLVYWLSALLWDFTIFFIT-----CCLLL--------
GVFKYGRLDIYITDYRFLD-TMLIFLLYGWSAIPLMYLLSFLFTRSTSAY------IILV
LFNYLSG--------IFTLLIDDSFQLGK-GFTNMSNATRNIVLNVLLLFPNYNLGKCIA
DYFT-------------FYQMKK-QCSK-EK-PPAYLN----CSKANNTKN--VYSLEEE
TIGKY--MIMMS---------------ITGFVFLLII

ENSGT00760000118965_2_Linker_2_3 (1718, 1815)

FFLETTL-WRLRTFFHQYIYFV-
IYKAFKKG---KVSKE--LSGESEDEDV-----QNERRRILGHPR---ELLNSAVLIKEL
TKVYFKY--PVIFA

PF00005 // ENSGT00760000118965_2_Domain_3 (1815, 1974)

VKNISLAIQKGE-CFGLLGFNGAGKTTTFKLLTGDEIVTSGKVFID
GFSITENTQK---SRIGYCPQSDALLEYMTGREIMIMYARL-WGISEPQIQQYVDKWLNS
LQLE-PHADKLISTY---SGGNKRQLSTAIALM---------GKPSVILLDEPTTGMDPV
AQRLLWDAVTWARESGKAIVI--SSHRME----ECDAFCT-----RLAIMVQGKFMCLGN
PQHLKSKFGNIYILNIKAKI-------YTHE---DKLDDLKFFITMT----F--------
-P-GSVL-----KHENQGILHYYIPSKDNTWGK--VFGILEEAKEQYNLEDYSISQITLE
QVFLTFANPIEQEKGCHEIHFQRPETLP--------------------------------
------------------------------------------------------------
---------------------------------------------

---------------------------------------------------------MAV
LRQLALLLWKNYTV---QKRKVLVT

PF12698 // ENSGT00760000118965_2_Domain_0 (86, 665)

VLELFLPLLFSGILIWLRLKIQSENVP--------
----------------------NATIYPG--QSIQELPLFFSFPP---PG--DAWELAYI
PSQ--SQAVKTITETARRTL-------VINMRARGFPSEK-------DFEDYIRYDNH-S
SNVLAAVVFEHTFNHSGEPLPLAVRYHLRFSYTRRNYMWTQTGSFFLKETEGWHTTSLFP
LF-PNPGPREPTSP--DGGEPGYIREGFLAMQHAVDRAIMQYHANASTRQLFEKLT-VIA
KRFPYPPFISDPFLVAIQYQLPLLLMLSFTYTALTIIRAVVQEKETKL------------
---------------------------KEYMRMMGLSSWLHWTAWFLLFFLFLLVAVSFV
TLLFCVKVK-KD----VAVLTHSDPSLV----------------------------LVFL
LCFATASVSFSFMVSTFFSKA---NMAAAIGGFLYFFTYIPYLFVAPRYNWMTLSQKLLS
CLLSNVAMAMGAQLIGKFEAK-GVGVQWRDLLSPVNVDDDFSFGQVLGMLLLDSVLYG--
LVTW

ENSGT00760000118965_2_Linker_0_1 (665, 758)

YVEAVLPGQFGVPQPWY-FF------VMPSY-WCGHPRTVLGKEE-EDDDPEKALR
TEYFEAEPEDLVAGI-KIKH-VTKVF-RVGSK--AAV

PF00005 // ENSGT00760000118965_2_Domain_1 (758, 913)

RDLTLNLYE---GQITVLLGH-N
GAGKTT--TLSMLTGLFPP-TSGRAYINGYDISQDMVQIRKSLGLCPQHDVLFDNLTVAE
HLYFYAQLKGLSHHK-CPEEVQRMLHVLGLEDKRDALSKFLSGGTKRKLSIGIALIAGSK
---V-LMLDEPT

ENSGT00760000118965_2_Linker_1_2 (913, 1182)

SGMDAISRRAIWDLLQQHKSDRTVLLTTHFMDEADLLGDRVAIMAKGE
LQCCGSSLFLKQK-YGAGYHMTLVKEPHCDPEAVTR---LVQHHVPTATLE---SRAGAE
LSFILPKESTHRFE---G-LFAKLEKHQKELGIASFGASVTTMEEVFLR--VGKLVDTSM
DIQAI--QLPALQYQH-ERRASDWAVDS---------------HLCGVM-DPTDGVGSL-
----IEDECTTAKLNTGLALHCQ-QFWAMFLKKAMYSLREW

PF12698 // ENSGT00760000118965_2_Domain_2 (1182, 1717)

KMVV-AQVLVPLTCVTLAL
LAVNYSSET-----FDDPMLELTLGAYGRTVV---PFAVPGASR-------LDQQLSERL
KDMLQAEGQEPRE-VL-----GDLEEFLIFRASVEGGGFSERCLVAMSFRDVGERTVVTA
LFNNQAYHSP-----------------------------ATALAVVDNLLFKQLCGPRAS
IVVSNYPQPRSALQAAKDQ-FNE-----GRKGFDIALNLLFAMAFLA---------ST--
FSILAVSERAVQAKHVQFVSGVHVATFWLSALLWDLISFLVP-----SLLLL--------
VVFKAFDVHAFTRDGHMAD-ALLLLMLYGWAIIPLMYLMNFFFSGAATAY------TRLT
IFNILSG--------IATFLM---VTIMRIPAVKLEELS-RTLDHVFLVLPNHCLGMAVS
SFHE-------------NFEMRR-YCTSSEVAAH-------YCRKYNIQYQQNFYAWSAP
GVGRF--VTSMA---------------ASGFAYLSL

ENSGT00760000118965_2_Linker_2_3 (1717, 1816)

LFLIETDTLWRLKTCLCAF-----
-RRRW---A--LTEGYAQTSAPPEDQDV-----VDERNRVLAPSMDSL--LDTPLVIKEL
SKVYQQR--APLLAV

PF00005 // ENSGT00760000118965_2_Domain_3 (1816, 1974)

DKMCLAVQKGE-CFGLLGFNGAGKTTTFKMLTGEETVTSGDAFVG
GYSISSEIGKVRQ-RIGYCPQFDALLDHMTGRETLVMYARL-RGIPERHIAACVENTLRG
LLLE-PHANKLVRTY---SGGNKRKLSTGIALL---------GEPSVIFLDEPSTGMDPV
ARRLLWDTVARARESGKAIII--TSHSME----ECEALCT-----RLAIMVEGQFKCLGS
PQHLKSKFGSGYSLRAKIRS-------DGQQ---EALEEFKAFVNLT----F--------
-P-GSVL-----EDEHQGMVHYHLPGADLSWAK--VFGILEKTKEKYAVDDYSVSQISLE
QVFLSFAHLQPPAEDEGP------------------------------------------
------------------------------------------------------------
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