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Query Results 

"ENSGT00760000118965_1"


Found:

ENSGT00760000118965_1


ENSMMUP00000024472 (view gene)
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---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTFFQGYNIPLW-
---KE-----EDFSA----------------HCWDG---YG-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ISKNLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
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---FWLSWGLIY-AGFIFIISIFITI----------VITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLGWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERRYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
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PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLREH---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FK-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMHLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAM
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMLN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTA-LI--SNFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEMRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFIFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTAREHLEVYAAVKGLRKVDAR-----LAITR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSHGLP00100021572 (view gene)
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-----------------------------IKQINVYHQTQALLCKNFLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWGLP-ILLGLYIG--LFS---YLGENNQFPEMPPQ--DLGRVDK--FNISSVM-I
VYTPISN------ITQQIMNKTKFVPFM------------------------------KG
-R--IIGVPNTSYMDEILLKN-----LPRAVGIIFSDTF-SY----KLKFFQGHAIPFL-
---RE------DLST----------------HCLMA---GD-DFLC-------ALSSY--
WSRGFVTLQTAINAAIIEITTNHSVMEELMSVTAINMKTLPF---------ISRDILQ--
NEIFILFCLIYFSSFIYFVSLDV-----------TKERKKYKDLMKMMGLRDSA------
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---FWFSWGLIY-ASFIFIISIFITI----------IITCNKIIVMTGFMVIFTLFFLYG
LSLVT--FLMSV----------------------------LLQKAALT---NLIV-----
FL-LTLFWGC--------VGFTALYRQLPSSLEWILSICSPFAFTAGMTQIIHLDYN---
------LNGVVFPDPSGDSYIMIAIFAMLAFDCLIYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NECHYSP
LFFLNWSSCFQHR-KTDNEV--FEKDIDPEHP-FDDYFEPIAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------EKVEAL--
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PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLHFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTVYNKNISEIQDL
EEIRM-MIGICPQY--NVQFDILTVKE-NLSLFAKVKGIHPQEVE-QKVQQILLELDMQN
IQNNFAKDLSEGQKR-KLTFGIAILGEPRV--LLLDEPTAGLDPFSRHQVWNFLKEH---
---------------RAHRVILFSTQFVDEAD----------------------------
--------------------I---------------------------LADRKVIFSNGR
LKCAGS--SVFLK---RKWGL---GYHL--SFYRN-E----------------------I
CDPEQI-TSFINYH--------------------IPDAKL----KTENKEKLVYT--LPS
ER--TNKFPDLFRDLDKYSGQ---------GMMSY--DISMS----TLKEVFMNVEGK-L
TTKQE----------------LE-HVEMV--------NDSESPNEVE----PACSSLH--
----EVQTP-V-----------------------GDMDLWSMQVCAIARL---------R
FLKLIRG-RKTLLTLLLIFGMALFPLIMEKIAYSMIVQ-TVDWEFKTELYFLSPGQLP--
QDLRTSLLII-----NH--TES-DIEDFVQSLKHQNILLEVDDFE----NRNG-TESLSY
N-GAIIVSGRP-KDYR---FSLVCNTKRLHCFP-IL-TNIISNGLLRMFN----------
----------QTQY--IRIERSPFSLNTF-------------IDWTGLPESSSFLFFVVC
SISPYIAMSSVSDYKKKS-KSQLWISG-LHPSAYWFGL-AVVDVNLF-------------
---NLILLLMYL---I-------------------------VATSLGYAVSLTFLTYVIS
FIFRKRKKNSGLWSFCFYIQ-----INFHLAFF---------------------------
-----------------WSFQRI----------QEHFREFNE---LNFDLSGVDLLVCLI
PYFQALLFIFVLRCME-LKYGKKVIQKDPFF-RISPQSRNAQPNPEEP--GD--EHEDVQ
AERIRTSTALT-TSNLD--EKPTIIASCLHKEYAGQKKNCFAKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEIFGLLGPSGAGKSSSIKMIAGITKPTAGEVE-LK--GFSSV-WGDQGED---M-IKF
LGYCPQENVMWPRLTMKEHLEVYAAVKGLRKGDTA-----ITISR----LVNAFKLHEHL
NVPVRKLAAGTT---RKLCFVLSILGDSPILLLDEPSTG----IDPTG-QHQMWQAIQRS
VENTERAVLLTTHHLAEAEVLCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQDLKRI-LGKDYILELKVKELSQVPLV
HTKILKFFPQAA--QQERYSSF--LTYKLPIGDVYPLSQAFHKLEEVKHTFNLE---DYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELENVD-DEVDT-TMRWKLLPNSNEP---------------------
ENSDORP00000009024 (view gene)
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---------------------------MGNREIQVCQQTWALLHKNILKKWR-----MKR
ETLME
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WMNA-FLLLLLLY--IYP---NDHQVNDFSSLNSM--DLGRVDS--FSGP-RFTI
AYTPLTN------TTQQIMKKVASTSFM----------------------------T--G
RE--VFGMSDEESIKEVTANY-----HEEIARVIFTDTY-SY----HLKFVLGKRIPEK-
---KE----HRDHTA----------------HCVEI---D-EDIDC-------QLSIF--
WKEGFVALQAAINAAIIEVTTNHSVMEELMSVTGKLMVVHPF---------IGQGGVT--
TDFFILFCIIAFSPFSYYASANV-----------TRERKKMKGLMKMMGLRDLA------
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---FWLSWGLLY-AGFIFIMALCLAL----------VIKSIQFFVMTDFMIVFTLFLLYG
LSTVTLAFLMSV----------------------------LVKKSFLT---GQLV-----
FL-LTIFWGS--------LGFTALYRYLPVSLEWILSIFSPFAFMLGMSQMLHLDYD---
------LNSNASPDPSS-SNLIIATNFMLAFDTFLYLALTM
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRYPP
LFFLKSSFWSPEQKP-EHMT--LDNVVDSDSS-LNDSFEPVSPEFHGKEGIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
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PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLALDIYEGQITAILGHSGAGKSTLLNVLSGLSVPTK--GSVTIYNKELSDAAEL
ENILQ-MVGVCPQS--NVQFDFLTVRE-NLRLFAKIRGILPQEVD-KEVNRVLLELEMKN
IQDVLAQNLSGGQKR-KLSFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2502)
AGLDPISRHRVWNLLKER---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLK-E----------------------I
CARENI-TSLVKQH--------------------IPNAKL----SAESEGKLVYT--LPL
ET--TCRFPELYKDLDNSPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AVDEL---------DTDIL-GDT-QVERA--------GDTERLMEME----HILSSLR--
----EMRKM-T-----------------------SGVALWAYQICAIAKV---------R
LLKLKHE-KKALLSLLLILAAGFCPLLLEYILIKIYQN-SYTWELSPHLYFLALGQPP--
QAPLTQLLII-----NK--TGA-SIDDFLHSVEHQNIALEVDKSG----TGTG-VDDPSY
N-GAIIVSGNE-KVPC----SWAKSKIRIWSFH-SL-YP---------------------
----------------------LPSQKIQ-----SNPF---
PF12698 // ENSGT00760000118965_1_Domain_4 (2502, 2768)
QYL-----GHTTFWLILAS
SCPPYIAMSSIDDYKSKT-WSQLRISG-LFPSAYWFGQ-ACVDIPLY-------------
---CFIFIFMYL---MDFALSFQET-----LFTVVNRI-IQIPCSIGYVLSLIFFTYVIS
FIFRKGRKNSGIWSFCFFVI-----TLFSVAGF-FF--ENYEN-IPLYCITFLIPPA---
--TLI--------GCLFISLDLI----------ML------SVFGEEGSRRTDPFLVLLI
PLLHFFI
ENSGT00760000118965_1_Linker_4_5 (2768, 2873)
FLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDALQNPEQPEG----EDEDVQ
MERVRTTNSLN-STNFD--ETPVIIASCLRKEYARKRKHCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEILGLLGHNGAGKSTSIKVITGDMKPTAGQVL-LK--GSSE-------GD----PLGF
LGYCPQEDVLWPSLTVREHLEVFAAVKGLSKGDKE-----VTITR----LVDALKLQDHL
KAPVKTLAEGVK---RKLCFALSILGNPSVLLLDEPSTG----MDPEG-QQQMWQAIRAT
VRNTEGAALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPAQGEPL
HEEILKLFPQAA--RQDRYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQNFDLE---DYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFD-EELDL-SVKWKLLPQEEP----------------------
ENSAPLP00000006668 (view gene)
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---------------------------RLQRNLSVFQQTKILLWKNVLIKWR-----MKM
QSFQEWMLS-LLFLPLMF--IVGN--FMLH-IPYPEVPHS--YLGQLDDPAYDAA-GVTI
AFTPITP------TTRQIMNAVALKSVM------------------------------TG
IK--LEAMDSERALEEAWISN------NEIIGVVFKNNF-TY----YLRFPTGNVAI-P-
---ND----NLGYID----------------TCYN----FS-VRYC-------DSPKY--
WYKGFLSLQSSIDAAIIEVVANHSVWEEMKSIAGVRMKSRSV---------IYSITLE--
YSYFMITIVMCFSSFMYFLSMNV-----------VRERKKLKVLMKTMGLQDIA------
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---FWLSWSLLY-AVYVLILSCLLTA-----------LVVQEAFYVSSFPAVLLLFFLYG
LACIHMVFMLCS----------------------------LLRTSKLA---GSMG-----
FL-ITFLFGC--------LSLAVLIENLPEPLKWFLGLFCPFAFNAGIAKVFHLEKY---
------GIGFSFSNLMEESYFLFSTYIMLIFDSVLYMLLAMYFDKVLPGK---YGIPHPA
FFCLKPSYWMRSRRG-CPEE-RPHSARSPEEP-PGDDVELVPAEFMGKEAIRLNNIKKAY
-------------KKK------D-----------------------------KKTEAL--
--R--GLSLNIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNVLSGLTLPSEETGSATIYDYKLSEIGDR
EEIRE-MIGICPQF--NVQFEVLTVKE-NLRTFAEIKGIKSREVE-REVQTILELLDISN
VQDTQAEKLSGGQKR-KLSIGIAMLGSPQV--LLLDEPTAGLDPLSRHQVWSLLKEQ---
---------------RAGRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAFISHGR
LKCVGS--SLFLK---KKWGI---GYHL--RIHVS-E----------------------S
CDTESV-TSLVKQH--------------------IPNVIF----SGHGQYELRYK--LPL
EN--VNKFPDLFRGLDSCSDR---------GIINY--GVSMT----TLEDVFLRLEEE-A
TLGQEDEH---------VP-GEE-WAEAG--------P--RCPEETE----PGSLLLS--
----GTSKAMV-----------------------SGAALWRQQVSAMAWV---------H
FLKLKGS-VKNLRSILLLYVVFLLPLVLQLALVAAWQS-MSAWELSSARYFMPLGKRA-P
-AETTSLLVH-----NS--TGS-GIEDFIHTLESQDLTVEITSQE----N---ITEELKH
N-GAIKVSREG-QSYR---FTILCHMEAVNCFP-VL-VNIISNALLRALN----------
----------STAH--IRIWSHPFFSI-----------DNPRFWDYFVSFYLIYMLLLFP
GFPPHFAMGYLQDYKT-GARAQLRVSG-LFPSAYWCGQ-ALVDVPLC-------------
---WLLLFSMFG---LQFAMSNK-------ISGSIGNIFLLVMGALGYGVSIVLFIYLIS
FIFRKGW-NCDFWSFILIVV-----CLVSFIISRVMDYTLDMS-VSLYLMSLLIPLY---
--PLL--------GVTINSE------------QIFVEDADLIAASPRNDVLIAVFA----
PYIHSVGFIFLLRYLE-IKYGRTVLRKDPVFSRISPRNESSHQHPEEQE----EEDEDVK
AERAAVRNAII-APSQE--EKSVIIVSNLCKEYKTKKAGSVFKKK--KKMATKNISFCVN
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGPNGAGKSTAIKMIAGETTPTAGQVL-LR--RREGATC-CLQDH--------
LGHCPQEDPLWPDLTVHQHLQVYAAVKGVRKEDTA-----AAVNR----IVNALELQDYL
KKSARKLSAGIT---RKLCFAMCMLGNPAVLLLDEPSTG----MDPKG-QRCVWKMIRAA
LKTKETGAILTTHYMEEAEAVCDRVAILVAGQL---------------------------
---------------------------RCIGSIQYLKSK-FGKGYLLEIKVKDPESTDLL
HTEVLRIFPSAA--RQERFPSL--LVYKVPMEDALPLSQSFSKLEEAKQNFSLE---EYS
F-SLNTLAQV----------------------------------------------FLEL
SREQEKDNFD-LALDG-AFEWKQLQQEDS----------------------
ENSMLEP00000014978 (view gene)
MSRVQQGQSRSPACSAHGERSWGLGFSPFRWLLGTAGPTHQAALPPLQLGWVLAFEIFIP
LVLFFILLGLRQKKPTISVKEAFYTAAPLTSAGILPVMQSLCPDGQRDEFGFLQYANSTV
TQLLERLDRVVEEGNLFDPARPSLGSELEALRQHLEALSAGPGTSGSHVDRSTVSSFSLD
SVARDPQELWRFLTQNLSLPNSTAQALLAARVDPPEVYHLLFGPSSALDSQSSLHKGQEP
WSHLGSNPLFRMEELLLAPALLEQLTCTPGSGKLGRILTVPESQKGALQGYQDAVCSGQA
AARARRFSGLADELRNQLDMAKVSQQLGLDAPNGSDSPPQAPSPRRLQALLGDLLDAQKV
LQDVDVLSALALLLPQGACTGRTPGPPASGAGGVANGTGAGTVVGPNATAEEGAPSAAAP
ASPDTLQGQCSAFVQLWAGLQPILCGNNRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHL
MTSNPKILYAPAGSEVDRVILKANETFAFVGNVTHYA----QVWLNISAEIRSFLEQGRL
QQHLHWLQQ-YVAELRL-----HP---EALNLSLDELPPA--L--RQDN--FSLP-SGMA
LLQQLDTIDNAACGWIQFMSKVSVD-I---------------------------------
----FKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRK-DGSLPPHVHYKIRQNSSFT-
---EK----TNEIR----------------RAYWRP-------------GPNTGGRFY--
FLYGFVWIQDMMERAIIDTFVGHDVVEPGSYV-----QMFPYPC-------YTRDDFLFV
IE
PF12698 // ENSGT00760000118965_1_Domain_0 (843, 1542)
HMMPLCM--VISWVYSVAMTI-------QHIVAEKEHRLKEVMKTMGLNNAV------
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---HWVAWFITG-FVQLSISVTALTA----------ILKYGQVLMHSHVVIIWLFLAVYA
VATIMFCFLVSV----------------------------LYSKAKLA---SACGGIIYF
LSYVPYMYVA--------IREEVAHDKITAFEKCIASLMSTTAFGLGSKYFALYEVA---
-GVGIQWHTFSQSPVEGDDFNLLLAVTMLMVDAVVYGILTWYIEAVHPEV---L------
----LAGQWADRSLG-VELA------VGTHP--PPQCHGGGPGLCHGEPALW--------
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---------------------------------------------------
ENSPVAP00000001851 (view gene)
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---------------------------MNKREISTCQQTWALLCKNFLKKWR-----MKR
ESLMEWLSS-LLLLLFLY--LYP---NIHEVNDFSSLPTM--YLGRVDS--FSEST-FXX
XXXXXXX------XXX--XXXXXXXXXX----------------------------XXXX
RE--VLGLSDEDSIKELTANY-----PGEIVRVIFTNTF-SY----HLKFSLGRRIPTM-
---KE----HGDHTA----------------HCYKI---NDSDVDC-------GVTEF--
WKKGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKIHPF---------ISQEGLI--
TDFFVFFCIISFSPFIYYASINV-----------TRERKRMKGLMTMMGLQNSA------
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---FWLSWGLLY-AGFIFITAFFLAL----------TIKSVQFVILTGFTVVFILFLLYG
LSLIALAFLMSV----------------------------LIKNSFLT---GLVV-----
FL-LTVFWGS--------LGFMALYRQLPASLEWTLSLLSPFAFMLGMAQLLHVDYD---
------LNSNAFPNSSNNSREIIATNLMLAFDIFLYLALTIYFEKILPXX---XXXXXXX
XXXXXXXXXXXXXXXXXX-X--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
--K--DLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAVLGHSGAGKSTLLNILSGLSVPTK--GSVTMYDNKLSEMADL
ENISK-LTGFCPQS--NVQFDFLTVRE-NLRLFAKIKGIQPHEMD-K-------------
----------------------------EI--FLLDEPTAGLDPFSRHQVWNFLKER---
---------------KTDHVILFSTQFMDEAD----------------------------
--------------------L---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-D----------------------M
CVREKI-TSLVKQH--------------------IPEAKL----SAESEGKLVYT--LPL
ER--TNRFPXXXXXXXXXXXX---------XXXXX--XXXXX----XXXXXXXXXXXX-X
XXXXX---------XIATL-GEV-QAERA--------ADTERLVEME----QILSSLN--
----ETTDI-L-----------------------GGMALWRQQICTIARV---------R
LLKLKHE-RKALLSLLLILGIGFCPVLLEYIILKMYQS-SYTWELSPQLYFLAPGQQP--
CDPLTQLLII-----NK--TXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
X-XXXXXLVMK-KSYS---FSLACNTKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSAH--IQTDRSTFFEKEQ-----NNPF---QFL-----FPVMSWLILAS
SCAPYIAMSSIDDSKNKA-WSQLRISG-LFPSAYWFGQ-ALVDVPMY-------------
---WLIFLFMYL---VDYILSIQNS-----LLKSIIQI-MQIPCALGYATSLIFFTYIIS
FIFRKGRKNSGIWSFCFFII-----TFFSLAML-LV--DNYEN-ASLYVVTFLIPHA---
--TLL--------GCMLLPFRLI----------FS--------------AGAAVFLISLI
PFLHFIIFVFILRCLE-WKFGKKSMRKDPVF-RISPRSSDVCKNPEEPEG----EDEDVQ
MERVRTENALN-STNFD--EKPVIIASCLRKEYIGKRKHCFSKRK--KKTATRNVSFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTSIKMISGDTKPTAGQVL-LK--GSSE-------GD----DLGF
LGYCPQENALWPNLTVREHLEVFAAMKGLRKADTA-----VAITR----LVGALQLQDQQ
KRPVNALSEGIK---RKLCFALSILGNPPVVLLDEPLW-----MDPEG-QQQMWQAIRAT
FKNTGRGALLTTHYMSEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKVYLLEMKVKTPTQVEPL
HSEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLETVKQSYDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELENFD-DELDP-SVKWKLLPQEEP----------------------
ENSMAUP00000010113 (view gene)
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-----------------------------MKEISVYQQTRALLHKNLLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
FLEWSFP-IILGLYMG--LFS---YFKENMLFPETPPQ--DLGRIDE--FNGSSKM-V
VYTPISN------ITQLIMNKTSFAPSM------------------------------KG
AR--IIGVPSKNDLDEVLLNN-----IPRAFGIVFNDTF-SY----KLEVFLMYGNPFV-
---K------EDLLA----------------HCWDI---YG-DVSC-------VLSRY--
WKKGFVTLQTAINAAIIEITTNHSVMEELMSVNAKTMKTLPF---------ITKDILQ--
YEFFILVCLLYFSSFMYFISRNV-----------TKERKRYKELIKIMGLQDSA------
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---FWLSWGLIY-VGFIFIISIFIAA----------IIASAQIIVMTGFLVIFTLFFLYG
LSLIAVAFLMAV----------------------------LLQKAILT---NLVI-----
FL-FTLLWGC--------VGFTVLHKELPTSLEWILSICSPFAFTSGMAKIISLDYN---
------LNGVVFPDPSGESYVILVTFSILAFDALIYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---SDRRYSP
LFFLNSSSCFR-QKSSSNQV--TERGIDPELP-SDDYFEPVAPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
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PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFFDIYENQITAILGHSGAGKSSLLNILNGLYVPTS--GLVTVYNKSLSEMQDL
KEVRK-ITGVCPQH--NVQFEALTVKE-NLTLFAKIKGILPQNVK-QEVQQIILELDMQN
IQDNLAEHLSEGQKR-KLTFGIATLGDPQI--LLLDEPTVGLDPLSRQRVWNFLKER---
---------------KANHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGS
LKCTGS--SVFLK---RKWGL---GYHL--SLFMD-E----------------------T
CDSEQI-TSFINHH--------------------IPDAKL----KAKTKEKLVYI--LPL
ER--TSKFPDFFRDLDKYSGQ---------GLMNY--EVSMP----TLNEVFMNMEGE-S
TTKQN----------------FE-KRETI--------RDTESFHEME----PAYPSLS--
----EVQRT-V-----------------------SPMRLWGMQVCAMARL---------R
ILKLKRE-RKAFLTFLFILGIALFPLITEKMANAVIEQ-KNNWEFKTELYFLSPGQLP--
EGLRTSLLVI-----NN--TGS-NIEDFIQSLKHQNIVLEVDDFE----NRNG-TESLSY
N-GAIIVSGRQ-KDYR---FSVVCNTKRLHCFP-VL-MNVLSNGILHMLN----------
----------HTQY--IRIEE-----DLI-------------ILWFGILEGVLFLLLVAC
SISPHIAMSSVSDYKKKA-DSQLWISG-LYPSAYWCGQ-AVVDVILF-------------
---SVVLLSSYF---TLYATKL---MHI---YLTSEVVLSIVILSFGCAASLVFLTYVIS
FVFGKKRKNSGLWSIFFFTV-----LTIMFKIL-LT--EFFVE-TLLITIMVLVPSF---
--SLI--------AFLIFLEMRA----------FQYYSESEE---TKYVLSGVDLLLCLI
PYFHTLLFIFVLRCLE-LKCGKNVMRKDPIF-RISPRSLKVQPNPVEHIGEDE--DEDVQ
AERIRTSAALN-TSNLN--ERPVIIANSLHKEYTGQKKSCFSKRT--KKVAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPNGAGKTSSVRMIAGITKPAAGEVE-LK--GCSSA-VGYQDDG-----TVK
FGYCPQENVLWPILTVKEHLELYAAVKGLRKEDAA-----IAISR----LVNAFKLHDQL
NVLVQKLAAGAT---RKLCFVLSILGDSSVLILDEPSTG----LDVSE-RQQVWQAIQAA
VKDNERGVLLTTHDLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILELKVNGTSQVPLV
HREIVKLFPQAA--RQERYFSM--LTYQLPITDVYPLSQAFHKLEAVKHSFNLE---EYS
L-SQCTLDKV----------------------------------------------FLDL
SKDQELETVH-EEADT-TVRWKLLPRLDEL---------------------
ENSCATP00000027890 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLYKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1495)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TN--VIGAPNNTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTFFQGYNIPLW-
---KE-----EDFSA----------------HCWDG---YG-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ISKNLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKL
ENSGT00760000118965_1_Linker_0_3 (1495, 1682)
DYN---
------LSGQGFFAHC---FTIT--------D-------PILLPLDYLDG---DERHYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDSLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2302)
TTGLDPFSRDQVWSLLREH---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDK---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMRLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGI
PF12698 // ENSGT00760000118965_1_Domain_4 (2302, 2704)
AIFPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDSLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNVISNGLLRMLN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDISFF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTA-LI--SNFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEMRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFVFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERVRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGKVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTAREHLEVYAAVKGLRKVDAR-----LTIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHSFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSGALP00000006898 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MRRPKRNLSVFQQTKILLWKNVLIKWR-----MKM
QSFQEWM
PF12698 // ENSGT00760000118965_1_Domain_0 (548, 1542)
LS-LLFLPLMF--IVGH--FMMY-MPYPEVPHK--HLGQLDDPAYNAT-GVTI
AFTPITA------ATRQIMNTVASKSVM------------------------------TG
IK--LEALDTERALEEAGILN------DEIIGVVFKNNF-SY----HLRFPAGNVVF-P-
---NE----NLEYID----------------TCYN----YS-GQYC-------ESPKY--
WYKGFLSLQSSIDAAIIEVVANHSVWEEMRTITGVRMKSRSV---------ISSITLE--
YSYFMITIVMCFSSFMYFLSVNV-----------VREKKKLKVLMKLMGLHDMA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-AIYVLVLSCPLTA-----------LVMNETFHNSSFSAILMLFFLYG
LACVHLVFMLCS----------------------------LLRTSKLV---GSLG-----
FL-ITFLFGC--------LSLSVLIEKLPEPLQWFLSLFCPFAFNVGIAKIFSLERY---
------GIGFSFSNIMEESYFLLSTYIMLTFDSVLYMLLAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKVLQGK---YGIPAPP
LFCLKPSYWMQSRRG-SPGE-GHRGAGSPEEP-PGDNVEPVPLEFRGKEAIRLHNIKKTY
-------------KKK------D-----------------------------KKTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GLSFTIYEGQITALLGQSGAGKTTLLNVLSGLTSPSE--GSATIYDYKLSEIGDR
EEIRE-MVGVCPQF--NTQFEVLTVKE-NLRTFAEIKGIKSKEVE-REVQNILELLDISS
VQDTQAEKLSGGQKR-KLSIGIAMLGNPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2300)
AGLDPLSRHHVWNLLKEH---
---------------RAGRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAFISRGR
LKCVGS--SLFLK---NKWGI---GYHL--RIHVS-D----------------------S
CDVENV-TCLVKQY--------------------VPKVIF----SGHGQYELRYK--LPL
EN--VNKFPDLFRGLDNCSDL---------GIINY--GVSMT----TLEDVFLRLEEA--
AVDPEDER---------VP-G-E-WAEGG--------A--RSPEEME----QGSLLLS--
----DTGRMTL-----------------------SSWALWRQQVSAMAWV---------H
FLKLKTS-VKNLLSILLLY
PF12698 // ENSGT00760000118965_1_Domain_4 (2300, 2771)
VVFLLPLILQLVLMTVWQS-MGAWELCSSRYFLPLRTRA-H
-DDTTNLLVL-----NS--TGS-GIEDFIHALESQDLAVEITSKE----N---ITEELKY
N-GAIKVSREG-QSYR---FTIFCHMEAINCFP-VL-VNIISNALLRPFS----------
----------STAH--IQVWSHPFTSI-----------DNARFWDYFVSFYLMYMLLLFP
GFPPHFAMGYLQDYKT-GARSQLQVSG-LLPSAYWCGQ-ALVDVPLC-------------
---WLLLFSMFG---LLFAMSNK-------VSGTFSSFFFLITNAFGYGVSIVFFIYLIS
FLFRKGW-NCDFWSFILIVV-----CIVTFIISRFMDYAVDIE-VSLYLLSLLIPTY---
--SPL--------IVMLNSE------------QIFIEDPSLTEGISNNNILIAIFA----
PYIHSVVFVF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
LLRYLE-MKYGRPVLRQDPIF-RIPPRKENSHQHPEEPE----EEDEDVK
AEREAVKNAIA-APSQE--EKSVIIVSNVYKEYKIKKAGSVFRKK--KKVAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
KNISFCVK
KGEVLGLLGPNGAGKSTVIKMIAGETALTAGQVL-LR--SRDAKPG-WPQDH----VLAY
LGHCPQEDPLWPDLTVYEHLKVYAAVKGVCKEDMA-----TVINR----IVNALQLQDYL
KKPTRKLPAGIT---RKLCFAVCMLGNPSVLLLDEPSTG----MDPNG-QRCIWKMIHAA
LSTHETGAVLTTHYMEEAEAVCDRVAILVAGQL---------------------------
---------------------------RCIGSIQYLKNK-FGKGYLLEIKVKDPETTDLL
HAEILRIFPSAA--RQERFPSL--LVYKVPMEDALPLSQSFSKIEEVKQNFNLE---EYS
F-SLNTLAQV----------------------------------------------FLEL
SREQEKDNFD-LTLDG-PFEWKQLQQEDS----------------------
ENSRBIP00000008086 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLVFFQGYNVPLW-
---KE-----EDFSA----------------HCWDG---YG-EFSC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ITKNLLH--
NEIFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGFIY-AGFIFIISIFITT----------IITFTKIIVMTGFMVIFILFYLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERRYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SGDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYN-NLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPKI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIDQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMRLWRMQIFAMAWL---------R
FLKLKRQ-AKVLLTLLLVFGIAV
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQHILLEVDDFD----NRNG-TDGLSY
N-GAIIVSGKQ-EDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IQIESSPFPLSHM-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLSMYL---ILYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTT-LI--SHFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEVRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFVFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEIFGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTVREHLEVYAAVKGLSKADAR-----LTIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----VDPTG-QQQMWQAIQAV
IKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HNEILKLFSQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSMICP00000023143 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKREISVCQQTWALIHKNFLKKWR-----MKR
ESLLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WLSS-LFLLLYLY--LYP---HGHSVHDFSSLPTI--DLGRVDS--FGEP-RFSI
AYTPVTN------TTKQIMEKVASASFL----------------------------E--G
RE--VLAMPDEESIQELKRHY-----PDYVVTAIFTNMY-SY----HLKFSVSHKIPTK-
---KE----HSDHTA----------------HCYGM---N-EDVEC-------EVSSF--
WEKGFVALQAAINAAIIEVTTNHSVMEELLSVTGKCMKLQSF---------IEQTGVL--
TDMLIVFCIISFSPFTYYAAVNI-----------TRERKRMKGLMVMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWVSWGLLY-AGFIFIMAIFLAL----------VIKSTQFIILTGFMVVFTLFLLYG
LSLIALTFLMSI----------------------------LVKKSFLT---GLIV-----
FL-LTVFWGN--------LGFTSLYRYLPASLEWILSLLSPFAFMLGMIQLLRSDYD---
------LNSNVLPDPSDGSYLIIPIYFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGRRNSP
LFFLKSSFWSQQQKP-DHVA--LEDEIDSDLS-SNDSFEPVSPEFNGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVLDIYEGQITAILGHSGAGKSTLLNILNGLSVPTK--GSVAIYNNKLSEMANL
ENIRM-LTGVCPQA--NVQFDFLTVKE-NLRLFAKIKGILPQEVH-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPKI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2399)
AGLDPFSRHRVWNLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVQENI-TSLVKQH--------------------IPDAQL----STASEGKVVYT--LPL
ER--TNKFPELYKDLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DIAIL-GEA-QVERT--------GDTERLVEME----QVISSLR--
----EIRET-I-----------------------GGVALWRQQICAIARV---------R
LLKLKHE-RKALLSLLLMLVVGLCPLLVGNIMAQIYQN-SYTWRLSPHLYFLAPGQQP--
RDPLTQLLII-----NK--TGA-SIDDFIHSVELQNIAVEVDAFG----IRNG-TDEP
PF12698 // ENSGT00760000118965_1_Domain_4 (2399, 2770)
VY
N-GAVTVSGNE-KNYN---FSFACNTKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSAH--IQTDRSTT-GHTQ-----SYSL---EFF-----VYTIFWLVVAS
SCPPYIAMSSIDDYKNKA-RSQLRISG-LFPSAYWLGQ-ALVDVPLY-------------
---LLILLFMYC---VDYILNSHDNMA--FIFPTISRA-IQIPCVVGYSLSLIFMTYVIS
FLFHKGRKNSGIWSFCFYVV-----TIVSVAGL-IA--ESVES-GI-QIYTFLVPPA---
--TLI--------GCFFSYFYFF----------AV------SLFTGE-SWGVTPFLIFLI
PFLHFIIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPQG----EDEDVQ
TERVRTANALS-STNYD--EKPVIIASCLRKEYAGKRKCCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
QGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSG-------RGD----ALGF
LGYCPQENALWPSLTVREHLQVYAAMKGLRKGDAE-----VTITR----LVGMLKLQDQL
KTPTKTLSEGMK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQQLKSK-FGKDYLLEMKVKTPAQVEPL
HAEVLRLFPQAA--RQERFSSL--MVYKLPVEDVRPLAQAFFKLENVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELEDFG-EEIDP-SVKWKLLPQEEP----------------------
ENSRROP00000044231 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----IKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HRDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFFCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMSLFLAL----------VIKSTLFIILSGFMVVFSLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATDFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRPP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSIPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2471)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYHH-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNVALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KSYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------
PF12698 // ENSGT00760000118965_1_Domain_4 (2471, 2719)
PSVH--IQTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-FQIPCAVGYSFSLIFMTYVIS
FLFHKGRKNSGIWSFSFYVI-----TVFSVAGF-VF--NIFES-DIPFIFTFLIPPA---
--TMI--------GCLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
SSHLL----------FS------PLFSEE-RMDVQPFLVFLI
PFLHFFIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSCSAP00000000698 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLLEWGLS-ILLGLCIA--LFS---NSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTYLQGYNIPLW-
---KE-----DDFSA----------------HCWEA---YG-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHSVMEELMSVTAITMKTLPF---------ISKDLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLALYFDKVLPYG---DERHYSP
LFFLNSSSCFQHQ-GTDNKA--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVNKEY
-------------KGK------S-----------------------------GKVEAL--
--K--GLLFDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEPTTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMHLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAVFPLIVENIIYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLQMLN----------
----------HTQH--IQIESSPFPLSHI-------------GFWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSVF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFAFVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SITMFVTA-LI--NNLDL-SILITTMVLVPSY---
--TLL--------GFKTFLEMRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFIFVLRCME-LKYGKKRMRKDPVF-RISPQIRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAARNISFCVQ
EGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPVLTAREHLEVYAAVKGLRKVDAR-----LAIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPILLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSPPAP00000007959 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRCMSVGQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDTPQMSSM--DLGRVDS--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAV---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEITTNHSVMEQLMSVTGVHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFPALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSQNLYLIIATLFMLVFDTLLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPAE---YGHRCSP
LFFLKSCFWFQHGRA-NHVV--LENETDSDPT-PNDCFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------C-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSRMADI
ENISK-FTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVQELEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSIT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVLSSFH--
----ETRKT-I-----------------------SGVALWRQQVCAIAKV---------R
FLKLKKE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-TIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSIACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSEH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPMAA
SFTPYIAMSSIGDYKKKA-HSQLWISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----VIFSIVATDL---NEYGF-IGLFFGTMLIPPF---
--TLI--------GSLLIFSEIS----------PDS------MDYLGASESEIVYLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-MNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTVNAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GE----PLGF
LGYCPQENVLWPNLTVRQHLEVYAAVKGLRKGDAM-----IAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQMEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDLE-EDFDP-SVKWKLLLQEEP----------------------
ENSPVAP00000001852 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHITMGQQTWALLCKNFLKKWR-----MKR
ETLLEWFFS-FLLVLFTY-LFSS---NVHQDNDFPQMPAV--DLGRVDN--FNDS-NYVI
AFAPESK------TTQEIMNKVASAPFM------------------------------KG
RT--IMGWPDEKSMNKLDLNY-----SMDAVRVIFNDNF-SY----HLKFFWGGRIPKM-
---KE----HRDHSA----------------HCQTV---D-EKVTC-------EGSMF--
WKKGFIAFQAAINAAIIEITTNHSVMEELMSVTGINMKILPF---------IAQEGIT--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYMKSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFIMATLMAL----------VVKSTRVVVLTGFA---------G
LSLITLAFLMSV----------------------------LVKKPFLS---GLVV-----
YL-LTVCWGS--------LGFTALYRHLPAFLEWTLCLLSPFAFTAGMAQLLHLDYD---
------VNANIHLDSSNNPNLIIAILFMLVFDTLLYLVLTLYFDKILPTE---YGRRRSP
CFFLKSSFWFQHQKV-DHVA--LENELDLDPS-SNDAFEPVPPEFRGKEAIRIKNLKKEY
------------KRGK------N-----------------------------ERVEAL--
--K--GLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNMLSGLSVPTS--GSVTIYNHSPSEAADL
ETVSK-LTGVCPQS--NVQFGFLTVRE-NLQLFAKIKGIQPHEVK-QEVQRVLQDLEMES
IQDILAQNLSGGQKR-KLTFGIAILGDPQI--LLLDEPTAGSDPLSRHRVWSLLKER---
---------------KLDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGI---GYHL--XXXXX-X----------------------X
XXXXXX-XXXXXXX--------------------XXXXXX----XXXXXXXXXXX--XXX
XX--XXXXXXLYKDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AMDES---------DSGIW-GQL-QSDRT--------KDPGSLVELE----QLLSSCH--
----ETKKA-V-----------------------RGMVLWRQQACAIAKV---------R
FLKLKNE-KKTLMTILLLLGISFFPQLLEHLFYELYKK-SYSWGLSPNMYFRSPGQPP--
QAPLTHLLVI-----NK--TGS-SIENFIHSLRQQNIALEVDAFG----TRYG-PNESSY
N-GAITVSGDD-KDHR---FSIACNTKRLNCFP-VL-MDIISNGLLGILN----------
----------SSEH--IQTDRSTYFEEHTS-------D-EYGYM-----SNAFFWIPVAA
CFTPYIAMSSIGDYKKKT-HSQLWISG-LYPSAYWFGQ-ALVDSPLY-------------
---FLILLLMQI---MDYIFNPDEI-----MFIIQNLL-IQILCSIGYVSSLIFLTYVIS
FIFRNGRKNSGIWSFFFLII-----TIFSIVATDI---NEYEF-VGLFPCTILIPPF---
--TLI--------GSLFIFSEIS----------PDS------MDYVGSSEHYILYLALLI
PYLQFFVFVFVLRCLE-TNFRKKSMRKDPVF-RISPRSSKVLPNPEEPEG----EDEDVQ
MERTRTANAVT-AAASG--EQPVIVASCLRKEYSGKKKNCFAKKK--KKVATRNVSFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVFGLLGHNGAGKSTTIQMVTGDTKPTSGQVT-LK--GSSE-------GD----DLGF
LGYCPQENALWPNLTVREHLEVFAAVKGLRKADAA-----VAITR----LVGALQLQDQQ
KRPVKALSEGIK---RKLCFALSILGNPPVVLLDEPSTG----MDPEG-QQRMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLSQVEPL
HSEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFKLEIVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELEDFD-DELHH-SVKWKLLPQEEP----------------------
ENSMLUP00000017519 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------FLQITTNHSVMEELMSVTGKNMKIHPF---------VSQGGTT--
MDIYLLFFLIFFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRHSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIATLLLVL----------IIKSIQFVIWTGFMVVFTLFFLYG
LSLIALAFLMSV----------------------------LIKIPFLT---GLVV-----
FL-LTVFWGS--------LGFTVLYRHLPASLEWILGFLSPFAFMLGISQLLRVDND---
------VNSNAFPAFSNYSSQIIAAHFMLAFDIFLYLVLTIYFEKILPNE---YEHQYSP
LFFLKSSFWSRQRNA-DHVA--LEDEIYADPS-SNDSFEPVSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKVKAL--
--K--DMAFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTMYSNKLSEMADL
ENISK-LTGICPQY--NVQFDYLTVRE-NLRLFAKIKGIPPQEME-QEIQRVVLELQMDS
IEDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KMDHVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CVQEKI-TSIVTKH--------------------IPDAKL----SAKCEGKLVYA--LPL
ER--TNKFPELYENLDLCPDL---------GIENY--GVSMP----TLNEVFLKLEGK-S
TVDEP---------GIATS-GEV-HAEGA--------EDTERLCEME----QVLSSLS--
----EMKER-L-----------------------GGMALWRQQICAIARV---------R
LLKLKQD-RKSLLSLLLILGIGVFSVLWDYIIFSTYDV-IYTWELSPHLYFLAPGQPP--
HDPLTQLLII-----NN--TGA-SIDDFIHSVELQNIALEVDASG----NRNG-IDDPSY
N-GAIIVSGHD-KNYT---FSLACNTKRLNCFP-VL-MDIVSNGLLRIVR----------
----------PSAR--IQTGRSTSLLE-LDIS-----V---SFT-----MSSLFLVFLSS
SYAPYIAMSSIDDYKNKV-WSQLRISG-LFPSAYWLGQ-ALVDVPLY-------------
---WLMFLLIYL---LEFILSFKEN-----MFEFILHN-EQIPCAIGSVPSLVFFTYIIS
FIFRKGRKNSGIWSLGYFVI-----THFGMVII-LV--GMSEN-ILLFFINLITPHT---
--ALV--------ACMILSFYHG----------WL------FSID------GELVLLFLI
PFLQLIVVIFILRCLE-WKFGKISMRKDPFF-RISPRSSDVHQNPEEPEE----EDEDVE
MERVRTANALN-STNFD--ERPAIIASCLRKEYTVRRKHCFSKKK--KKIATRNVSFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3054)
GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSSE-------GD----PLGF
LGYCPQEKGLWPNLTVRQHLDVFAAVKGLRKADAT-----VTITR----LVEALKLQEEQ
KRPVKALSEGIK---RKLCFALSILGNPSAVLLDEPTTG----MDPSG-QQQMW------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSHGLP00000002330 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------IKQINVYHQTQALLCKNFLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWGLP-ILLGLYIG--LFS---YLGENNQFPEMPPQ--DLGRVDK--FNISSVM-I
VYTPISN------ITQQIMNKTKFVPFM------------------------------KG
-R--IIGVPNTSYMDEILLKN-----LPRAVGIIFSDTF-SY----KLKFFQGHAIPFL-
---RE------DLST----------------HCLMT---GD-DFLC-------ALSSY--
WSRGFVTLQTAINAAIIEITTNHSVMEELMSVTAINMKTLPF---------ISRDILQ--
NEIFILFCLIYFSSFIYFVSLDV-----------TKERKKYKDLMKMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-ASFIFIISIFITI----------IITCNKIIVMTGFMVIFTLFFLYG
LSLVT--FLMSV----------------------------LLQKAALT---NLIV-----
FL-LTLFWGC--------VGFTALYRQLPSSLEWILSICSPFAFTAGMTQIIHLDYN---
------LNGVVFPDPSGDSYIMIAIFAMLAFDCLIYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NECHYSP
LFFLNWSSCFQHR-KTDNEV--FEKDIDPEHP-FDDYFEPIAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLHFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTVYNKNISEIQDL
EEIRM-MIGICPQY--NVQFDILTVKE-NLSLFAKVKGIHPQEVE-QKVQQILLELDMQN
IQNNFAKDLSEGQKR-KLTFGIAILGEPRV--LLLDEPTAGLDPFSRHQVWNFLKEH---
---------------RAHRVILFSTQFVDEAD----------------------------
--------------------I---------------------------LADRKVIFSNGR
LKCAGS--SVFLK---RKWGL---GYHL--SFYRN-E----------------------I
CDPEQI-TSFINYH--------------------IPDAKL----KTENKEKLVYT--LPS
ER--TNKFPDLFRDLDKYSGQ---------GMMSY--DISMS----TLKEVFMNVEGK-L
TTKQE----------------LE-HVEMV--------NDSESPNEVE----PACSSLH--
----EVQTP-V-----------------------GDMDLWSMQVCAIARL---------R
FLKLIRG-RKTLLTLLLIFGMALFPLIMEKIAYSMIVQ-TVDWEFKTELYFLSPGQLP--
QDLRTSLLII-----NH--TES-DIEDFVQSLKHQNILLEVDDFE----NRNG-TESLSY
N-GAIIVSGRP-KDYR---FSLVCNTKRLHCFP-IL-TNIISNGLLRMFN----------
----------QTQY--IRIERSPFSLNTF-------------IDWTGLPESSSFLFFVVC
SISPYIAMSSVSDYKKKS-KSQLWISG-LHPSAYWFGL-AVVDVNLF-------------
---NLILLLMYL---I-------------------------VATSLGYAVSLTFLTYVIS
FIFRKRKKNSGLWSFCFYIQ-----INFHLAFF---------------------------
-----------------WSFQRI----------QEHFREFNE---LNFDLSGVDLLVCLI
PYFQALLFIFVLRCME-LKYGKKVIQKDPFF-RISPQSRNAQPNPEEP--GD--EHEDVQ
AERIRTSTALT-TSNLD--EKPTIIASCLHKEYAGQKKNCFAKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEIFGLLGPSGAGKSSSIKMIAGITKPTAGEVE-LK--GFSSV-WGDQGED---M-IKF
LGYCPQENVMWPRLTMKEHLEVYAAVKGLRKGDTA-----ITISR----LVNAFKLHEHL
NVPVRKLAAGTT---RKLCFVLSILGDSPILLLDEPSTG----IDPTG-QHQMWQAIQRS
VENTERAVLLTTHHLAEAEVLCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQDLKRI-LGKDYILELKVKELSQVPLV
HTKILKFFPQAA--QQERYSSF--LTYKLPIGDVYPLSQAFHKLEEVKHTFNLE---DYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELENVD-DEVDT-TMRWKLLPNSNEP---------------------
ENSCANP00000000376 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTRQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLVFFQGYNVPLW-
---KE------DFSA----------------HCWDG---YG-EFSC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHLVMEELMSVTAITMKTLPF---------ITKNLLH--
NEIFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IITFTNIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-GTDKKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KRK------P-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-IIGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPKI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2303)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLHEME----LAHSSFS--
----EMQTA-V-----------------------SDMCLWRTQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIA
PF12698 // ENSGT00760000118965_1_Domain_4 (2303, 2704)
VFPLIVENIMYVMLNE-KIDWEFKTELYFLSPGQLP--
EEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IQIESSPFPLSHM-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLSMYL---IFYIENM---QYL---LITSQIVFALVIVTLGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SVIMFVTT-LI--SNFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEVRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFVFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERRRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEIFGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSLV-LG------------H
LGYCPQENVLWPMLTVREHLEVYAAVKGLSKADAR-----LAIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSTBEP00000006006 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNIKHKNVYQQTQALLYKNFRKKWR-----MKR
ESLLEWSFP-VLLGLYMG--LSS---YFTENVQLSELPPL--DLGRVDK--LNRS-T-IV
VYTPVST------TTQQIMNKTALAPIL------------------------------KX
XX--XXXXXXXXXXXXXXXXX-----XXXXXXXXX-XXX-XX----XXXXXXXXXXXXX-
---XX-----XXXXX----------------HCQFK---YG-DIMC-------SLTRY--
WNRGFVTLQTAINAAIIEITTNHSVMEKLMSVTATNMKTLPF---------LSKARFQ--
NEMFILYSMLYFSSFIYFLSLNV-----------TKERKQYKDFMXXXXXXXXX------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---XXLSWGLIY-AGFIFIISIFITI----------IIMSTQIIVMTGFMVIFTLFFLYG
LSLIALTFLMSV----------------------------LLKKAGLT---NLVV-----
FL-LIFFWGC--------MGFTAFYKQLPSSLEWILSICSPFAFTAGMTQIIHLDFN---
------LSGVTFPDPSGNSYIMIATFFMLAFDGLIYLVLALYFDKLLPYG---GECHYSP
EFCLNSSSCFKHERT-DNQV--TEKEIDSEHL-PEDCFEPVAPEFQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
--K--GLLFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGSGKSSLLNILNGLSVPTE--GSVTIYNKNPSEIQDL
EEIRK-ITGICP-F--NVQFDTLTV-G-NLSLXXXIKGIHQQQVE-QEVQQILLELDMQN
IQDKLAKFL--GQKR-KLTFGIAILGDPQV--LLLDDPTAGLDPFSRHQVWSFLRER---
---------------RADRVILLSTQFMEEAD----------------------------
--------------------I---------------------------LADRKVVMSNGR
LKCAGS--SVFLK---RKWGL---GYHL--SLYRN-E----------------------I
CDPEQI-ASFINHH--------------------IPDAKL--K-TENKE-KLVYT--LPL
ER--TNKFSDLFSDLDKCSDQ---------GLMSY--DISMS----NLNEVFIQLEEK-S
TIEQDFEQ--------------A-EI--R--------DSES-LNGME----TARSSLP--
----EMQR-TV-----------------------NDMGLWRMQVFAMARL---------R
FLKLKRE-RKALLTLLLAFGTALFPLIVETIFNAVLNHHGIDWEFKNDLYFLSPGKLP--
HEPLTSLLII-----NNTES---DXXXXXXXXXXQNILLEVDDFK----NRNG-TDALSY
N-GAIIVSGKQ-RDYR---YSVVCNTKRLHCFP-IL-MNIISNGILQMFN----------
----------HTQH--IRVERSPFPV-------------NPMLLDTGLPEGSLFLLHLAS
SMSPFIAMSSISDYKK-QAKSQLWISG-LYPSAYWCGQ-ALVDINIF-------------
---VLILFSTYL---IIYLVNMLEI------YIT-HRIV-LALXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-----XVLVITANIILM-SRYSP-IFIITSMLLLPST---
--I--VG------GFPSFIDMX-----------XXXX--XXXXXXXXXXXXXXXXXXXXX
PYFQALLLFFVLRCME-LKCGKQTMLKDPVF-RISPQSRSVQQNPEEPV----DEDEDVQ
AERIRTEAALT-TSNLD--EXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX
X
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
XEVLGLLGPNGAGKSTSIRMISGIIKPTAGEVE-LK--ECSSGL-------------GH
LGYCPQGNVLWPTLTMKEHLEVYAAVKGLRKGRPR-----AITRX----XXXXXXXXXXX
XXXXXXXX-XXX---XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-XXXXXQAIQAT
AKNKERGVLLITHYLAEAEALCDRVAIIVSGKL---------------------------
---------------------------RCIGSIEHLKSK-FGKDYILELKVKDISQVTLV
HMEILKIFPQAA--QQERHSSL--LVYKLPMA-VYPLSQAFHKLETVKHNFNLE---EYT
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVENFD-EEVDT-NMRWKLLHSEEP----------------------
ENSSARP00000010186 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
KN--VIGVANRTHLDEIVEDH-----LPYAAGIIFNDMF-SY----NLTFFQGFSIPFL-
---KE-----DTFSX----------------XXXXX---XX-XXXX-------XXXXX--
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPF---------ISKDFLQ--
NEMFIFYCLLYFSPLTYFLSLNI-----------TKERKKRKDVMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AAFIFIFSIVITI----------VITTTNIIILTGFMVIFTLFFLYG
MSLXXXXXXXXX----------------------------XXXXXXXX---XXXX-----
XX-XXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIIHQDYD---
------MNGVTFPDPSGYSYKMIATFFVLAFVALLYLVLALYFDKILPYG---NKSRYSP
LFFLNSSSRFQHQRI-NHKV--IEKEIDTEHP-SDDYFEPIPPEYQGKEVIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
--K--GLFLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GEITAILGRTGAGKSSLLNVLSGLSVPTE--GSVTIYNKNISEMQDL
EDIRK-RTGVCPQF--NVQIDMLTVKE-NLRLFAKIRGIQPQAVE-QEVQKVLLELSMQN
IQDQLAQHLNEGQKR-KLTFGIAILGDPQV--LLLDEPTMGLDPFSRHQVWTFLKER---
---------------QEGRVILLSTNFLDEAD----------------------------
--------------------I---------------------------VADRKVIMSDGR
LKCAGS--SVFLK---RRWGL---GYNL--SLYRN-E----------------------L
CDPEKI-TSFINHH--------------------IPEAKL--K-AKDKE-KLVYT--LPL
ER--TNAFPELFSDLDQGSGQ---------GVLSY--DVSMS----TLSDIFVKLEGE-S
AISQXXXX--------------X-XX--X--------XXXXXXXXXX----XXXXXXX--
----XXXX-XX-----------------------XXXXXXXXXXXXXXXX---------X
XXXXXXX-XXXFWPLLLVFGIAIYPFIMERIVYGLLDQ-TNDWEFKSEFYFLSPGQLP--
QETRTSLLII-----NNTES---NIEDFIKSLKQQNILLEVDDFE----NRNG-TEDPSY
N-GVIIVSGKQ-KDYK---FSIVCNTKRLHCFI--L-MNII-SGLLGMLN----------
----------SXXX--XXXXXXX------X------XXXLLMLSWFGLPESTFFLFLVVC
NISPYFAMSSVSDYQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------
---XXXXXXXXX------XXXXXXX------XXX-XXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-----XVSLILFDIIVM-HESRI-FTYIAAMMLFPPV---
--ILI--------GFIKVIVEK-----------NYLY--HESVEDTAITISGADFLLCLI
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX----XXXXXXX
XXXXXXXXXXX-XXXXX--XXXXXXXXXXXXX-XXXXXX--XXXX--XX-XXXX----XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--XXXXXXX-XXXXX----XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX----L
PF00005 // ENSGT00760000118965_1_Domain_5 (2991, 3091)
VALFELHEQL
NVPVYKLTAGAT---RKLCFLLSILGDSPILLLDEPSTG----MDPAG-QQKMWRMMQSA
IKNTGKGALLITHYLAEAEALCDRIAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYILELKVKETSQMASV
HGEILKLFPQAA--QQQRYSSF--LTYKLPMMDVHPLSQAFHKLEVAKHKLNLD---EYS
L-SQCTLDKV----------------------------------------------FGEL
SKEQLGE--L-DEVDT-SMRWRLLPYSDDP---------------------
ENSMUSP00000036338 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRLGQQMWALLCKNWLRKFR-----MRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLLEWLFS-LLLILFVY-QLSS---NLHQVHDAPEMSVV--DLGRVDN--FNDS-NYMM
VFAPESE------ATHEIMNKVASAPFM------------------------------KG
RT--IVACPDEKSMNELDLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPKT-
---KE----HKDHSA----------------PCEPL---N-NKMIC-------ENSAF--
WEKGFVAFQAAINAGIIEMITNHSVMEELMSVIGSNMKMPPF---------IAQGGVA--
TDFFIFFCVISFSSLIYYLSVNI-----------TQERQYMTTLMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLMY-AGFILVVAVLMSL----------IVKSAQVVVLTGFMVVFLLFLFYG
LSLITLSFLMSV----------------------------LIKKPFLT---GLAI-----
FI-LTVFWGS--------LGFTALYKHLPAFVEWTLCFLSPFAFTTGMAQLIHLDYD---
------VNSNVNLNSPNNSYLIMATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKITLSK---YGHQRSP
LFFLKSSYWFKRRGA-SHVV--LENEIDSDPS-LNDSLEPVSPEFQGKEAIRIKNLKKEY
------------S-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINTLSGLSPPTT--GSVTIYNQTVSEMDDS
DAVLT-ITGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQQVLQDLEMEN
IQDILAQNLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2448)
AGLDPLSRHRIWNLLKER---
---------------RAGRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------A
CDPEGI-TSLVKKH--------------------ISDARL----TTQSEERLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIEDY--GVSMT----TLNEVFLKLEGK-S
MADES---------DVGIC-GRL-QSDGA--------RDMESLVELE----QVL-SLD--
----SSGSS-V-----------------------SGMALWRQQLCAVAKV---------R
FFKLKNE-RKSLMTVLLLFGISFVPQLLEHLVYKVYHK-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NR--TGS-SIDNFVHALRQQGIALDLDALG----TRNG-TEEALY
N-GAITVLGEE-KALR---FSVACNAKRLNCFP-VL-MDIISNGLLG
PF12698 // ENSGT00760000118965_1_Domain_4 (2448, 2771)
IFN----------
----------SSER--IQTDRSTVFEEHML-------Y-EYGFM-----SNAFFWIPVAA
SLTPYIAMGSISDHKKKV-LSQLWTSG-LYPSAYWCGQ-ALVDIPIY-------------
---FLILFLMQI---MDSVFSSEEF-----ISVMESLL-IQIPCSIGYASSLIFMTYVIS
FIFRNGRKNSGIWSFFFLIV-----TIFFIIATDI---NEYGF-LELLICTFLVPPF---
--TLI--------GSLLIFSEVS----------YDS------VDYLGTSESQLVFLALLI
PYLHFLLFFF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-RYLRKKSLRVDPVF-RISPRSCPAVPNPEEPGE----EDEDVQ
MERVRTTGAMA-TLQTD--EKPVIIASCLRKEYIGRTKRCFSKMK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTIPTAGQVF-LK--GSGG-------GA----ALGF
LGYCPQENVLWPNLTVKEHLELYAAVKGLKKKDAV-----VTITR----LVNALKLQDHL
KALVRTLSEGVK---RKLCFVLSILGNPPVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPSQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSEAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFG-EEANS-SVKWKLLPQEEL----------------------
ENSRBIP00000026566 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MIIYLYFSYM------------------------------VG
RT--VIGTPDEETMDIVLPKK-----YHQMVGVIFRDTF-SY----QLKFNWGYRIPII-
---KE----HSEYTG----------------NCTKT---DYNL-FL-------IL-----
---------------------------HGIPFIGINMKMLPF---------LSKGEIM--
NEW
PF12698 // ENSGT00760000118965_1_Domain_0 (844, 1542)
FLFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FAVFWGC--------LGFTVLHRQLPLSLGWVLSLFSPFAFIAGMDQITHLDHY---
------LRGVIFPGPSGDSYIMIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEMNSENS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHDGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITDM
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEFFFDMVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2486)
AGLDPFLRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEN------LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--AT-AP----GLNEVFLNLEGK-S
AIDEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVLRE-THCWEFSPTMYFLSLEQIP--
KMPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNCFP-VL-MGIVSNALTGIFN----------
----------FTEL--IQTESTSFS
PF01061 // ENSGT00760000118965_1_Domain_4 (2486, 2723)
RDDI-------------VLDFGFIDGSIFLLLITN
CISPFIGMSSISDYKKKV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWERTFVLVVCIIGCTASLIFLTYI--
-------------------------LICVTTIL-VS--TQYEN-LNLILCMIFIPSF---
--TLL--------GYVILLIQL
ENSGT00760000118965_1_Linker_4_5 (2723, 2873)
D----------FMYMTNLDSLDSRINEVNKTILLTTLI
SG----VSFFVIRCLE-RSMEMKYMNKDPV--LISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLA--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMIAGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPEENSLWPTLTMKEHLELYAAVKGLDKDDAA-----LSISR----LVEALELQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQI-QILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQQLKNK-FGKDYLLEIKMKEPSQVEAL
HTEILKLFPQAA--RQERYSSL--MAYKLPVEDVHPLSRAFFKLEAVKQTFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSAMEP00000011084 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHINVGQQTWALLCKNFLKKWR-----MKR
ETFLEWFFS-FLLVLFAY-RLSS---NLHQVNDFPQLPAM--NLGRVDN--FNDS-NYVI
AFAPESK------TTQEIMNKAASAPFM------------------------------KG
RK--IMGWPDEKSMDYLDLNY-----SIDAVKVIFNDTF-SY----HLKFFWGGRIPKM-
---KE----HRDHSA----------------HCQVM---D-EKITC-------EGSVF--
WEKGFVAFQAAINAAIIEITTNHSVMEELMSITGINMKILPF---------VAQAGVA--
TDFFIFFCIISFSAFIYYVSVNV-----------TQERQYIKSLMMMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFIVATLMAL----------IVKSAQVVVLTGFVVVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRHLPAFLEWTLCLLSPFAFTAGMAQLIHLDFD---
------VNSNIHLDPSDNPYLIIATLFMLVFDALLYLALTLYFDNIFRTE---YGHRRSP
WFFMKSSFWFQHQRA-DHVA--LENETDSDSS-PNDSFEPVSPEFHGKEAIRIRNLKKEY
------------RKGN------H-----------------------------EKVEALKV
-MP--GLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTIYNHTLSEMADF
ETISR-LTGVCPQS--NVQFGFLTVKE-NLRLFAKIKGIQPHEVE-REVQQVLRDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGSDPLSRHRVWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDSI-TSLVKQH--------------------IPDAKL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DAGIW-GEL-QSNRT--------KDTGSLVELE----QVLSSFK--
----EKRKS-I-----------------------SGMALWRQQLCAIAKV---------R
FLKLKNE-KKTLLTILLLFGISFCPQLLEHLFYELYQK-SYSWGLTPNMYFLSPGQPP--
QAPLTHLLVI-----NK--TGS-SIDNFIHSLRQQNIALEVDAFG----TRSG-PNEPSY
N-GAITVSGDD-KDHR---FSIACNTKRLNCFP-VL-MDIISNGLLGIFN----------
----------SSEH--IQTDRSTYFEEHMS-------Y-EHGYL-----SNAFFWIPVAA
CFAPYIAMSSIGDYKRKA-HSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLVMQI---MDYVFSPDEI-----IFIIQNLL-VQTLCSIGYISSLVFLTYVIS
FIFRNGRKNSGIWSFFFLMI-----TIFSIVATDL---NEYGF-LGLFLCTILIPPF---
--TLI--------GSLFIFSEIS----------PDS------TDYLGTSEQQIVFLALLI
PYLHFCIFVFVLRCLE-VNFRKKSMRKDPMF-RISPRSSGIFPNPEEPEG----EDEDVQ
IERRRTTNAGT-VADFD--EKPVIIASCLRKEYAGKKRKCFAKRK--KKVAIRNVSFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVIGLLGHNGAGKSTTIKMITGDTNPTAGQVI-LK--GNSE-------GD----SLGF
LGYCPQENVLWPNLSVREHLEVFAAIKGLKKGDAT-----VTITQ----LADALKLQDQL
KLPVRALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FKDTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPTQVEPL
HCEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVKWNLLPQEDP----------------------
ENSCAPP00000017609 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------ILLG
PF12698 // ENSGT00760000118965_1_Domain_0 (555, 1386)
LYIG--LFS---FFGENMLFPEMPPQ--DLGRVDK--FNSS-SVKL
VYMPISN------ITQQIMNKTTFLPFM------------------------------KG
RI--IXXX-XXXXXDKMLSQN-----LPHAMGIIFTDTF-SY----KLKFWLMNSFPLD-
---SC-----FLFSNSSPVMMVSMFFXXXXXXXXXX---XX-XXXX-------XLSKY--
WNNGFVALQTVINAAIIEITTNHSVMEELMSVTAINMKTLPF---------VSKSVPQ--
IGIFILFCLIYFFPFIYFVSLDV-----------TKERKKHKNLMKTMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IVTSIKIFIMTGFVVIFTLLCLYG
LSLVS
ENSGT00760000118965_1_Linker_0_3 (1386, 1682)
SYIXXXX----------------------------XXX-----------------
------------------------------------------------------------
-------XXXXXXXXXXXXXXMISIFAMLVFDCFIYLLLALYFDKILPYG---NECHYSP
LFFLNSSSCFQSRKT-DNKV--FEKDTDSELH-FDDYFEPVAPEFQGKEAIRIRNVKKDY
-------------KEK------S-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GFNFDIYESQITAILGHSGAGKSSLLNILSGLSVPTQ--GSVTVYDKNISEMQDL
EEIRK-MIGVCPQY--NVQFDILTVKE-NLSLFAKIKGIHPHEVE-QKVRQVLLELDMEN
IQNNLAEDLSEGQKR-KLTFGITILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2513)
AGLDPFSRYRVWSFLKER---
---------------RENHVILFSTQFVDEAD----------------------------
--------------------I---------------------------LADRKVIMFNGR
LKCAGS--SVFLK---RKWDL---GYYL--SVYKN-E----------------------I
CDQEQI-TSFINHH--------------------IPDAKL--K-TENKE-KLVYT--LPL
ER--TNKFPDLFRDLDKCSSQ---------GMMSY--DISMS----TLSEVFMNIEGK-S
TINQGFGH--------------L-EM--M--------SNSESFNEMQ----PAYPSLP--
----EVQK-PV-----------------------SDMERWRMQVCAIARL---------R
FLKLIRE-RKTLLILL--------------------------------------------
-------LII-----NHTES---DIEDFIQSLKHQNILLEVDDFK----NRNG-TNALSY
N-GAIIVSGKQ-K---------VCFVTWVHCFP-VL-MNIISNGLLRMFN----------
----------QTQY--LRLERSPLSS----------------VFWPGLLDGS
PF12698 // ENSGT00760000118965_1_Domain_4 (2513, 2718)
LFLLFVVC
-ISPYIAMSSVSDYKK-KAKHQLWISG-LYPSAYWFGQ-ALVDINLF-------------
---NLILLLVHL---IGYLIIITNN------YISSRAIFGMVTTTFGYAVSLIFLTYVIS
FVFRKRKYSGLW--------------TFCFYVNSLIW-ENFHL-TTIISTMIFVPSS---
--TM--------NVFLMFLLER-----------AYAH--YADSEETKFDLSEAELLVCLI
PYFQALLFIFVLRCME-LKYGKNVMRKDPVF-RISPQSPEARPNPEEPG----DEDEDVQ
AERIRTSTALT-TSNLD--EKPTIIASCLHKEYAGQKKNCFSKRK--KKLATRNISFSIK
KGLKWIPY------------------MLQILNVK-LK--ECGTALD-DQGED----MVTL
PGYCPQENVLWPRLTMKEHLEVYAAVKGLRKGDSA-----VIISR----LVNTFKLIIN-
-----------------------------------------------F-LIHFRQAIQMS
VKNKDRAILLTTHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILQLKVEELSQVPLV
HSEILKCFPQAA--QPERYSTL--LXXXXXXXXXYPLSQAFHKLEQ--------------
----------------------------------------------------------EF
SKEQELENVN-EEVDE-TMRWKLLPHSEEP---------------------
ENSP00000467271 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRKISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
VYTPVTN------TTQQIMNKVASTPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVTFTNTY-SY----HLKFLLGHGMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSSFIYYASVNV-----------TRERKRMKALMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIRSTQFIILSGFMVVFSLFLLYG
LSLVALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGC--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRPP
LFFLKSSFWSQTQKT-DHVA--LEDEMDADPS-FHDSFEQAPPEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2381)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLIYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QAEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKHE-RKALLALLLILMAGFCPLLVEYTMVKIYQN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIQSVEHQNIALE
PF12698 // ENSGT00760000118965_1_Domain_4 (2381, 2718)
VDAFG----TRNG-TDDPSY
N-GAITVCCNE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSVH--IRTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNFEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVV-----TVFSVAGF-AF--SIFES-DIPFIFTFLIPPA---
--TMI--------GCLF
ENSGT00760000118965_1_Linker_4_5 (2718, 2873)
LSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFTLRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYAGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSG-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDP-SVKWKLLPQEEP----------------------
ENSP00000342216 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRRMSVGQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDTPQMSSM--DLGRVDS--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAV---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFPALYTRLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPAE---YGHRCSP
LFFLKSCFWFQHGRA-NHVV--LENETDSDPT-PNDCFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------C-----------------------------ERVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSRMADI
ENISK-FTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVQELEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2398)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSIT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVLSSFH--
----ETRKT-I-----------------------SGVALWRQQVCAIAKV---------R
FLKLKKE-RKSLWTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-TIDNFLHSLRRQNIAIEVDAFG----TRNG-TDD
PF12698 // ENSGT00760000118965_1_Domain_4 (2398, 2771)
PSY
N-GAIIVSGDE-KDHR---FSIACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSEH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPMAA
SFTPYIAMSSIGDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----VIFSIVATDL---NEYGF-LGLFFGTMLIPPF---
--TLI--------GSLFIFSEIS----------PDS------MDYLGASESEIVYLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-MNCRKKLMRKDPVF-RISPRSNAIFPNPEEPEG----EEEDIQ
MERMRTVNAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GE----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAM-----IAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKLKNLAQMEPL
HAEILRLFPQAA--QQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDLE-EDFDP-SVKWKLLLQEEP----------------------
ENSMMUP00000048627 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS
PF12698 // ENSGT00760000118965_1_Domain_0 (550, 1542)
-FLLLLCLY--IYP---HSHQVNDFSSLLTT--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----QLKFLLGHEMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFSLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIPIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2768)
-VL-MDIVSNGLLGMVK----------
----------PSVH--IQTERSTFLENGQ-----DNPI---AFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FVFHKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NVFES-DIPFIFTFLIPPA---
--TMI--------GCLFLSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFII
ENSGT00760000118965_1_Linker_4_5 (2768, 2873)
FLFILRCLE-WKFGKKSMRKDPFF-RISPRSSEVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAK-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSHGLP00000001515 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKRKISVCQQTWALFCKNLIKKKR-----MKR
DTLMEWLYS
PF12698 // ENSGT00760000118965_1_Domain_0 (550, 1542)
-AFLLLILC--TFY---TLHEVYDFSSMPPV--DLGRIDS--FNDS-AFVI
AYTPFNK------TTQRIMNKVSSASFM----------------------------T--G
RK--VIAFPDEENMTELISTH-----YEDVVRVIFTSPF-SY----HLKFLRGSRIPII-
---KE----HQDHSV----------------HCHEV---R-DSFDC-------GISQF--
WTEGFVALQAAINAAIIEISTNHSVMEELMSVTGKHMKIDPF---------IGQEGKI--
TDFFICICIICFSPFTYYVSLSV-----------TRERKKMKCLMTMMGLQDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLLY-AGFVFILTLFLAF----------IIKSVQFVILAGFMVVFSLFFFYG
LSLIALAFLMSI----------------------------LLKKPFLT---GLVV-----
FL-LTVTWGG--------LGFVALYRYLPVSLEWILSFFSPFAFTLGMAQLLHLEFD---
------MNSNA--DSMGDPNLIIATIFMLFLDSLFYLALTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRHSP
LFFLKSSFWCQKKTA-NHVA--LENETESE-F-SDEAFEPVSTEFHGKEAIRIRNLTKEY
-------------RRK------P-----------------------------KNVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLAFDIYEGQITAVLGHSGAGKSTLLNILTGLCVPTK--GWVTIYNNKLSEITDL
ENISE-LTGVCPQS--NVQFDFLTVKE-NLRLFAKIKGIQPNEVD-NEVHRVLQELEMKN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHRVWNFLKER---
---------------KAGHVILFGTQFMDEAD----------------------------
--------------------I---------------------------LADRKLFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CVHERI-TSLVKHH--------------------IPDAKL----SAENEGKLIYI--LPL
ER--TNKFPDLYRDLESCPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
DIDQP---------DLCAL-GDV-EAEGP--------RETGRLFEMG----ETVSSLS--
----GMSET-Q-----------------------AGLALLWQQVCAIARV---------R
FLKIKHE-RKALFILILIFGSGLLHILAANAHKIFYPE-DYCWDLSPHMYFLTPDQQP--
QKLLSNLLII-----NK--TGA-SIDDFIHSLEKQNIALEVDAFG----TRNG-TEELSY
N-GAIIVSGNG-KNYS---FSLSCNTKRLNCFP-VL-VDIVSNGLLGMLS----------
----------PSGS--IHTDRSTYPDVV--------GF---NNL-----AYLISWIVLMS
CLSPYISMTSIDDYKNKA-QLQLWISG-LNPSAYWFGQ-ALVEVPIY-------------
---FSLIFFMYL---VYYTSKVKGD-----IYTAVDVL-IEILYIVGYSVSVIFMTYVIS
FIFRNGRKNSGIWSFCFYFV-----TLVSAAVM-G---DFLGD-IFLYCVSALIPFA---
--TLV--------GCTMLHFDVR----------N-----P------------NILFLILS
PYVHLIIFLVILRCLE-CKFGKKTMRKDPVF-RISPRTSSVFHNLEDPEG----EDEDVQ
LERVRTSNALT-SPNFE--QKPAIIASCLRKEYTEKK-CLFFKRK--KKTAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIRMITGETKPSAGQVL-LR--GSSS-------PE----PQGF
LGYCPQENVLWPSLTVREHLQVFAAVKGLRKGDAE-----VAVTR----LVEAFKLQDQL
QAPVRTLSEGMK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQIWKAIRAT
LRDTERGVLLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPTQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLSRAFFKLETVKQSFDME---EYS
L-SQSTLEQVFLELSK--EQEMDDF-----------------------------------
---------D-EELDP-SVKWKLLPQEEP----------------------
ENSRBIP00000012069 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRCMSVGQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMRC-------EGSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYIMSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---ALVV-----
FL-LTVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCFWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSGMADI
ENISK-LTGFCPQS--NVQFAFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVQDLEMEN
IQDILAQNLSDGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2396)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGNLVELE----QVLSSFH--
----ETRKP-I-----------------------SGMALWRQQVCAIAKV---------R
FLRLKNE-GKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNS-T
PF12698 // ENSGT00760000118965_1_Domain_4 (2396, 2771)
DDPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHTD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FLFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILLPPF---
--TLI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GD----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADVLKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSFL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGVLE-DDFNP-SVKWKLLPQEEL----------------------
ENSMODP00000007666 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKRERSFCQQTQALLCKHLIKKWR-----MKR
ESLSEWLLS-LLLCLLVF--FFL---MTSSISQVPEVPPV--DLGRIDE--FNDSDFL-I
KYMPVTN------TTQQIISKMALASFM------------------------------KG
IN--ITGTTDEKAL----SHG-----FYDTIAVIFHDMF-SY----ELK-SWGYRVPFN-
---KE----LHEHSA----------------HCRIF---DEEI-SC-------YLEEY--
WKRGFVAFQAAINSAIIEITTNHSVMDQLMSVNGINMKVHPF---------IAQFSIV--
RDIIILICIISFSPMIYFVSLNV-----------TRERKNVMEWMTMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLLY-AGYIFVLASLLAV----------IITSNEFVIMTGYFTVFILFLLYG
LSLVALTFLLCE----------------------------LIKKPVLT---GLVT-----
FF-LTVFWGS--------LGLVSLYQQFPASLEWILSLLSPFAFVFGINHILRMDYN---
------LRSFAFPDPSGDSHQLLAIFFMLVFDIILYLALVLYFNKILPRKKIELGPGEGS
FSFLPHSFQ--RP-P-VIVK--GINDTNSTY--WPDSFEPVPPEFHGKETIRIRNIKKEY
-------------KRK------S-----------------------------EK
PF03193 // ENSGT00760000118965_1_Domain_2 (1675, 1728)
VEAL--
--K--GFQLDIYEGQITAILGHSGAGKSTLINILSGLSEPTE--GSVSIYNNNLSEMEDLEEIKK-ITGVCPQF--NVHVDFLTVRE-NLRLYAKIKGIPPEKVE-QEVQRVSLELEMKSIQDTLAANLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWHLLKEH------------------KADHVTLFSTQFMDEAD------------------------------------------------L---------------------------LADRKVFISSGKLKCAGS--SLFLK---RKWGI---GYHL--SLHKN-E----------------------SCDSERI-TSLIKHH--------------------IPDAKL----TAEREEKLVYT--LPLER--TDLFPDLYSDLDNCIGQ---------DIVNY--GVSMT----TLTEVFLKLEGK-TTIDDA---------DFESL-GQE-Q---T--------RHSETFVEPE----QTFASLF------GEKMESV-----------------------SGMALWKQQIWAVARV---------RFLKLKHD-RKVLRSLSLLLVVTLLPFAFESIVYDLLHK-NVPWRFTPDEYFLSPGQQS--QHSLSSLLIV-----NN--TGS-NIEDFVSSLKHQNIVLEVDDFE----NKNG-TTDLSYN-GAIIVAGKK-KDYR---FSLACNTKRLNCFP-VL-MNVVSNGLLKMLN--------------------STKQ--ITTERTTFSYDFE-------------PSSITNVEKDLLLILATTSLSPYLAMSSIADYKVRQTQAQLRISG-LYPSAYWCGL-ALVDVPLN----------------FMILLLLYS---IIYFIN---LGFY---TINTGILFIQIICTIGYAGSSVFFTYIISFIFKKGRKNSGIWSTFFFIT-----SLFTFAFN-QK--TNFEL-SGMFCCIAFIPFF-----TLF--------GCTMLFLENL----------A----------YDTYDINENIFFVILIPYLHCIIFLFVLRCLE-MKYGKQCMGKDPVF-RIFPTNSDAGTNPEEPED----EDEDVQAERARTLREMT-TSNLD--EKPVIIASCLRKEYEGKKKSCFAKRK--KKVAARNISFCVKKGEVLGLLGHNGAGKSTSIRMITGDTRPTAGKVV-LK--GSKT-SQ-QRNIN----ATNILGYCAQENSLWQNFTVREHLEIYAAVKGMKKGDAM-----VTISR----LKDALKLQDYMKVPIKELSTGIT---RKLCFALSILGNPAVILLDEPSTG----MDPEG-QQQIWQTIRAIFKKKESGAILTTHYMAEAEALCDRVAIMVSGKL------------------------------------------------------RCIGSIQHLKSK-FGKDYLLEIKVKESGQVRHLHEEILKLFPRAA--RQDRYSSL--MVYKLPVEDVHPLSQAFSKLEAAKHTFNLE---EYSL-SQSTLEQV----------------------------------------------FLELSKEQELGDFE-EELDT-NIKWKLLPQEEP--
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLINILSGLSEPTE--GSVSIYNNNLSEMEDL
EEIKK-ITGVCPQF--NVHVDFLTVRE-NLRLYAKIKGIPPEKVE-QEVQRVSLELEMKS
IQDTLAANLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWHLLKEH---
---------------KADHVTLFSTQFMDEAD----------------------------
--------------------L---------------------------LADRKVFISSGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHKN-E----------------------S
CDSERI-TSLIKHH--------------------IPDAKL----TAEREEKLVYT--LPL
ER--TDLFPDLYSDLDNCIGQ---------DIVNY--GVSMT----TLTEVFLKLEGK-T
TIDDA---------DFESL-GQE-Q---T--------RHSETFVEPE----QTFASLF--
----GEKMESV-----------------------SGMALWKQQIWAVARV---------R
FLKLKHD-RKVLRSLSLLLVVTLLPFAFESIVYDLLHK-NVPWRFTPDEYFLSPGQQS--
QHSLSSLLIV-----NN--TGS-NIEDFVSSLKHQNIVLEVDDFE----NKNG-TTDLSY
N-GAIIVAGKK-KDYR---FSLACNTKRLNCFP-VL-MNVVSNGLLKMLN----------
----------STKQ--ITTERTTFSYDFE-------------PSSITNVEKDLLLILATT
SLSPYLAMSSIADYKVRQTQAQLRISG-LYPSAYWCGL-ALVDVPLN-------------
---FMILLLLYS---IIYFIN---LGFY---TINTGILFIQIICTIGYAGSSVFFTYIIS
FIFKKGRKNSGIWSTFFFIT-----SLFTFAFN-QK--TNFEL-SGMFCCIAFIPFF---
--TLF--------GCTMLFLENL----------A----------YDTYDINENIFFVILI
PYLHCIIFLFVLRCLE-MKYGKQCMGKDPVF-RIFPTNSDAGTNPEEPED----EDEDVQ
AERARTLREMT-TSNLD--EKPVIIASCLRKEYEGKKKSCFAKRK--KKVAARNISFCVK
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIRMITGDTRPTAGKVV-LK--GSKT-SQ-QRNIN----ATNI
LGYCAQENSLWQNFTVREHLEIYAAVKGMKKGDAM-----VTISR----LKDALKLQDYM
KVPIKELSTGIT---RKLCFALSILGNPAVILLDEPSTG----MDPEG-QQQIWQTIRAI
FKKKESGAILTTHYMAEAEALCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEIKVKESGQVRHL
HEEILKLFPRAA--RQDRYSSL--MVYKLPVEDVHPLSQAFSKLEAAKHTFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EELDT-NIKWKLLPQEEP----------------------
ENSOGAP00000001088 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWMSS-LFLLLCVY--LYP---HGHEAIDLSSLPTK--DLGRVDS--FNES-SFSI
AYAPVTK------TTQQIMKKVASVPFL----------------------------S--D
ER--VLGMSDEAITGELAGSY-----SDEMIRVIFTDTY-SY----HLKFLTGHKIPSW-
---KE----HRDHTA----------------HCYEA---Y-EDVYC-------EVSLF--
WRRGFVALQAAINAAIIEVTTNHSVMEELMSVNGKYMKIPPF---------IGQAGVG--
TDFLLFLFVISFSSFTYYASINV-----------ARERKKMKGFMAMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------IMKSTQFVFLTGFMAIFSLFLFYG
LSLIALVFLMSV----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWIFSLLSPFAFMLGITQLLRSDYD---
------LNSNALPHLSDGSSLLTLINFMLAFDTFLYLMLAIYFEKILPNE---YGRQHSP
LFFLKSSFWSQQQKTEQHMA--LEDEIDFDLS-SNDSFEPVSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------E
PF03193 // ENSGT00760000118965_1_Domain_2 (1674, 1718)
KIEAL--
--K--DLAFDIYEGQITAILGHSGAGKSTLLNILSGLAVPTK--GSVTIYNNKLSEMAHLENIIK-LTGVCPQA--NVQFNFLTVKE-NLRLFAKIKGILPQEVD-REIQRVLLELEMKPIQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKEC------------------KKDRVVLFSTQFMDEAD------------------------------------------------I---------------------------LADRKVFLSKGKLKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------VCIQENI-TSLVKQH--------------------VPDAKL----SAASEGKLVYT--LPLER--TNRFPELYKDLDSCPGL---------GIENY--GVSLT----TLNEVFLKLEGK-SAIDES---------EIAML-GEV-HVEST--------GDTERLVEME----QVISSLK------EIKET-M-----------------------GGMALWRQQVCAIARV---------RLLKLKHE-RKAILSLLLILVIGLSPLLIQNILLKMYQH-IYTWDISPHLYFLAPGQPP--RDPLTQLLII-----NK--TGA-NIDDFIRSVEHQNIALEVDALG----IRNG-TDDPAYN-GAITVSGDG-KNYR---FSLACNTKRLNCFP-VL-IDVVSNGLLAMVE--------------------PSTHERIKTDRSTTGGSMQ-----NDPF---AFI-----AYTLFWLILGASCPPYIAMSSIDDYKNKA-WSQLRISG-LFPSAYWFGQ-ALVDVPLY----------------FFIFLFMFV---MDYTLNYEDG-----VFTVVNYI-FQIPCAVGYTLSLIFVTYVIAFIFRKGRKNSGIWSFCFFVV-----TILAISGF-VF--VIYES-DLHFVITFLCPPA-----TLL--------GCMILYFYLF----------YT------AGFVGG-TVGVETYLIFLIPLVHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRDSDVCQNPEQPEG----EDEDVQMERERTANALS-STNFD--EKPVIIASCLRKEYTGKRKCCLSKRK--NKIATRNVSFCVKKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--SSGG-------GD----TLGFLGYCPQENALWPNLTVREHLEVYAAVKGLRKGDAK-----TTISR----LVNALKLQDQLKVPTRTLSEGVK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL------------------------------------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPAQVEPLNAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFLKLEKVKQNFNLE---EYSL-SQSTLEQV----------------------------------------------FLELSKEQELDDFD-EELDP-SVQWKLLPKEEY------------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLAVPTK--GSVTIYNNKLSEMAHL
ENIIK-LTGVCPQA--NVQFNFLTVKE-NLRLFAKIKGILPQEVD-REIQRVLLELEMKP
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKEC---
---------------KKDRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CIQENI-TSLVKQH--------------------VPDAKL----SAASEGKLVYT--LPL
ER--TNRFPELYKDLDSCPGL---------GIENY--GVSLT----TLNEVFLKLEGK-S
AIDES---------EIAML-GEV-HVEST--------GDTERLVEME----QVISSLK--
----EIKET-M-----------------------GGMALWRQQVCAIARV---------R
LLKLKHE-RKAILSLLLILVIGLSPLLIQNILLKMYQH-IYTWDISPHLYFLAPGQPP--
RDPLTQLLII-----NK--TGA-NIDDFIRSVEHQNIALEVDALG----IRNG-TDDPAY
N-GAITVSGDG-KNYR---FSLACNTKRLNCFP-VL-IDVVSNGLLAMVE----------
----------PSTHERIKTDRSTTGGSMQ-----NDPF---AFI-----AYTLFWLILGA
SCPPYIAMSSIDDYKNKA-WSQLRISG-LFPSAYWFGQ-ALVDVPLY-------------
---FFIFLFMFV---MDYTLNYEDG-----VFTVVNYI-FQIPCAVGYTLSLIFVTYVIA
FIFRKGRKNSGIWSFCFFVV-----TILAISGF-VF--VIYES-DLHFVITFLCPPA---
--TLL--------GCMILYFYLF----------YT------AGFVGG-TVGVETYLIFLI
PLVHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRDSDVCQNPEQPEG----EDEDVQ
MERERTANALS-STNFD--EKPVIIASCLRKEYTGKRKCCLSKRK--NKIATRNVSFCVK
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIKVITGDTKPTAGQVL-LK--SSGG-------GD----TLGF
LGYCPQENALWPNLTVREHLEVYAAVKGLRKGDAK-----TTISR----LVNALKLQDQL
KVPTRTLSEGVK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPAQVEPL
NAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFLKLEKVKQNFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVQWKLLPKEEY----------------------
ENSPVAP00000001854 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHRKQKNVYQQTQALLCKNLLKKWR-----MKR
ESSLEWGIP-VLLGLYMG--FFS---HFRQNSRFPEMPPQ--DLGRVDK--FNSS-MV-V
VYTPISN------ITEQIMNKTAFAPFL------------------------------NG
KE--VIGAPNQQSMDKIILDH-----FLTAVGIVFNDNF-SY----KLKFFQGHVIPFL-
---KE-----EHFSA----------------HCWNT---DS-DFAC-------SLAKY--
WNTGFVTLQTAINAAIIQIVTNHSVMENLMSVTATNMKTLPF---------ISKYILQ--
NEMFIFYCLLYFSSFIYFASLDV-----------TKERKMHKDLMKMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIIITM----------IIISTQIIVMTGFMVIFTLFFLYG
LSLIALTFLMSV----------------------------LFKKTVLI---NLVV-----
FL-LTLFWGG--------VGLTAFYRQLPTSVEWILSICSPFAFTAGMAQIIHLDYN---
------MNGVTFPDPSGDSYVMIATFFVLAFDAFFYLVLALYFDKILPYG---NERRYSP
LFFLDSSSCFQRR-RTHDKT--TEKEIDPVHP-SDDYFEPIAPEFQGKEAIRIRNVKKEY
-------------KEK------S-----------------------------GKVEAL--
--K--GLLLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSLLLNILN-LSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--SIQFDMLTVKE-NLRLFAKIKGILPQEVE-QEVQRILLELDIQN
IQDNLAKHLSEGQKR-KLTLGIAVLGDPQV--LLLDEPTAGLDPFSRHRVWSFLKER---
---------------KADRVTLLSTNFMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SDFLK---RKWGL---GYHL--SLYRN-E----------------------I
CDPEKI-TSFINHH--------------------IPDAKL----KTESKEKLVYT--LPV
ER--TDKFPDLFSDLDKGSGQ---------GVVSY--DISTS----TLNEVFMKVEGK-S
TVEQD----------------FE-QAEMR--------RDTESLHEME----PASSSFP--
----EMRKA-V-----------------------SDLELWRMQVCAIARL---------R
FLKLKRG-KKALRTLLLVFGISLFPLIVETIYDAVLVQ-RSDWEFKPELYFLSPGQLP--
QDSLTSLLII-----NN--TES-SIEDFIQSVKHQNILLEVDNFK----NRNS-TDDLSY
N-GAIIVSGEQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQY--IRTERGSYPFNYV-------------FFWTGLPEASLFLLLTLC
SVSPYIAMSSVSDYKKRA-KSQLWISG-LYPSAYWCGQ-ALVDINLF-------------
---ILILFLMYL---IFCIANM---ANI---YITSRIVFALVVISIGYAASLVFLTYVIS
FIFRKKRKNSGLWSFCFFFI-----SASFFDII-LS--HLNLP-ILIFGMV-LFPPF---
--TLN--------GFLVFLAERD----------LEHQTKYQD---PNYDLNAVDFLVCLI
PYLQALLFIFVLRCME-VKCGQKIMQKDPVF-RISPPSREARPNPEEPVD----EDEDVQ
AERIRTATALT-TSNME--EKPIVIASCLHKEYAGQKKNCFSKRK--KKIAARNISFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCCSV-S------------GH
LGYCPQENVLWPSLTVREHLEVFAAVKGLRKADAT-----VAISR----LVDSFKLHEQL
NVPAQKLTAGTT---RKLSFVLSILGNSSILLLDEPSTS----MDPAG-QQQMWQMIQTA
IKNTEKGALLTTHYLAEAEAICDRLAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-LGKDYNLELKVKETSQVNLV
HTEILKLFPQAA--QQERYSSF--LTYKLPVADVHPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FVEL
SKEQEAGDFD-EEVNT-TMKWKLLSHSDDP---------------------
ENSCGRP00000018732 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTMKEISVYQQTRALLHKNLLKKWR-----MKR
ESF
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWSIP-IIVGLYMG--LFS---YFKENMQFPEIPPK--DLGSVDE--FNGSSIM-V
VYTPISN------ITQLIMNKTTLAPSM------------------------------KG
TT--IIGVPSKKDLDEVLLNS-----IPHALGIIFNDTF-SY----KLEVFLMYGNPFL-
---K------EDLLA----------------HCWDI---YG-DISC-------SLSRY--
WKKGFVPLQTAINAAIIEITTNHSVMEELMSVNAVTMKTLPF---------ITKDIFQ--
YEFFILFCLLYFSSFMYFISRNV-----------TKERKKYKELMKIMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIISIFIAI----------IITSAKIIVMTGFLVIFTLFFLYG
LSLITVAFLMAV----------------------------LLQKAILT---NLVI-----
FL-FTLFWGC--------VGFTVLHKQLPTSLEWILSICSPFAFTSGMAKIISLDYN---
------LNGVVFPDPSGESYLILVTFSILAFDALIYFVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NEHSYSP
LFFLNSSSCLQ-QKSSSNQV--LERGIDPELP-SDDSFEPVAPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFLDIYESQITAILGRSGAGKSSLLNILNGLYVPTS--GLVTVYNKNLSEMQDL
KEIRR-ITGVCPQH--NVQFDALTVKE-NLTLFAKIKGILPQKVK-QEVQQIILELDMQN
IQDNLVEHLSEGQKR-KLTFGIATLGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2301)
TVGLDPFSRQRVWSFLKER---
---------------KANRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVILSNGS
LKCTGS--SVFLK---RKWGL---GYHL--SLFID-E----------------------T
CDLEQI-TSSINHH--------------------IPDAKL----KAKTKEKLVYI--LPL
ER--TSKFPDFFRDLDKYSDQ---------GLVNY--EVSMS----TLNEAFMNMEGE-S
TTKQN----------------FE-KRETI--------RDTESLQEME----PAYPSLS--
----EVQRT-V-----------------------SPMKLWGMQVCAIARL---------R
ILKLKRE-RKAFLTFLLIFG
PF12698 // ENSGT00760000118965_1_Domain_4 (2301, 2759)
IALFPLIMEKMANAVIEQ-KNDWEFKTELYFLSPGQLP--
EGLRTSLLVI-----NN--TES-NIEDFIQSLKHQNIVLEVDDFE----NRNG-TESLSY
N-GAIIVSGRQ-KDYR---FSVVCNTKRLHCFP-IL-MNVLSNGILHMLN----------
----------HTQY--IRIEEAVFSSDLI-------------MLWFGILEGLLFLLLVAC
SISPHIAMSSVSDYKKKA-DSQLWISG-LYPSAYWCGQ-AVVDINLF-------------
---NVILLSSYF---TLHVTKL---MHI---YLTSEVVLSIVVVLFGCAASLVFLTYVIS
FVFGKRRKNSGLWSICFFTV-----MAVMFKIL-LT--EFFSE-TLLIIMMVLVPSF---
--SLI--------AFLIFLEMRS----------FQHYSEFGE---IKYGLSGVDLLLC
ENSGT00760000118965_1_Linker_4_5 (2759, 2873)
LI
PYFHTLLFIFVLRCLE-LKCGKNVMRKDPIF-RISPRSVKVQPNLEEHIGEDEDEDEDVQ
AERIRTSAALS-TSNLN--ERPVIIANGLYKEYAGQKKCCFSKRT--KKVAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPNGAGKTSSVRMIAGITKPAAGEVE-LK--GSSSA-VGYQGDG-----TIK
FGYCPQENMLWPILTVKEHLQVYASVKGLRKKDAT-----IAISR----LVNAFKLHDQL
NVLVQKLAAGAT---RKLCFVLSILGDSSILILDEPSTG----LDVSE-QQQVWQAIQAA
VKDNDRGVLLTTHDLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILELKVNETSQVPLV
HRDIVKLFPQAA--RQERYFSL--LTYQLPITDVYPLSQAFHKLEAVKHSFNLE---EYS
L-SQCTLDKV----------------------------------------------FLEL
SKDQELETVH-EEADT-TVRWKLLPRLDEL---------------------
ENSFDAP00000021349 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKKQINVYRQTQALLYKNFLKRWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWGLP-ILLGLYAI--LFS---SLGESYQFPEMPPQ--DLGRVDK--FNRSSIM-I
VYTPTSD------ITQKIMNKTTFVPFM------------------------------KE
ER--IVGVPNASSMDQILLKN-----VPYAVGIIFNDTF-SY----KLKLFQGYAIPFL-
---RE-----EDLST----------------HCWMA---GG-DFSC-------TLSAY--
WNRGFVTLQTVINAAIIEITTNRSVMEELMSVTAINMKTLPF---------ISRDILQ--
NEIFILFCLIYFSSFIYFVSLDV-----------TKERKKCKDLMKMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-AGFIFIISIFITI----------IITSNQIIVMTGFMVILTLFFLYG
LSLITLVFLMSV----------------------------LLEKAALT---NLIV-----
FL-LTLFWGC--------VGFTALYRQLPSPLEWILCICSPFAFTAGMTQIIHLDYN---
------LNGVTFPDPSGDSYIMIAIFAMLAFDCLIYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPHG---NERHYSP
LFFLNWSSCFKHR-KTDNKI--FEKDIDPEHT-FDDYFEPIAPEFQGKEAIRIRNVKKEY
-------------KGK------C-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLHFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTVYNKNISERQDL
EEIKK-MIGICPQY--NVQFDILTVKE-NLSLFAKIKGILPQEVE-QKVQQILMELDMQN
VQNNLAKDLSEGQKR-KLTFGIAILGDPRV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2298)
AGLDPFSRHQVWNFLKER---
---------------RENHVILFSTQFVDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---RKCGL---GYHL--SFYRN-E----------------------M
CDPEQI-TSFIHLH--------------------IPDAKL----KTESKEKLVYT--LPS
ER--TNKFPDLFRDLDKCSGQ---------DMMSY--DISTS----TLNEVLMSVEGK-S
TTKQE----------------FE-HREMV--------SDSENLSEIE----PGCSSLH--
----EVQTP-V-----------------------SDMELWRMQLCAIARL---------R
FLKLIRG-RKTLLTLLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2298, 2723)
IFGMALFPLIMEKIALSMTVQ-TVDWEFKTELYFLSPGQLP--
QNLRTSLLII-----NH--TES-DIEDFIQSLNHQNILLEVDDFK----NRNG-TEGLSY
N-GAIIVSGKQ-KDYR---FSLVCNTKRLHCFP-IL-MNIVSNGLLRMFN----------
----------QTQY--IRMERSPFSLDTI-------------LIWTGLPESSSFLFFIVC
SISPYIAMSSVRDYQRKA-KSQLWISG-LYPSAYWFGL-AVVDVNLF-------------
---NLILLLMYL---IVFLTRM---TGI---YTESQIIFAVVATSLGYAVSLIFLTYVIS
FIFRKRRKSSGLWSLCFYIV-----LTVTFTLF-LF--GHFYL-GEIISSMVFVPLF---
--TLG--------AFQLFLVKR
ENSGT00760000118965_1_Linker_4_5 (2723, 2873)
F----------QDYNEKFND---VNFNLSGVDLLVCLI
PYFQALLFIFVLRYME-LKYGKQVIRKDPFF-RISPHSRDAQTNPEEP--GD--EHEDVQ
AERIRTSTALT-TSNLD--EKPTIIASCLYKEYAGRKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEIFGLLGPNGAGKSSCIRMIAGITKPTAGEVE-LK--GGSSV-CSD--QD---M-LRC
LGYCPQENVMWPRLTMKEHLEVYAAVKGLRKGVAA-----IIISR----LLNAFKLHEHL
DLPVRKLTAGTT---RKLCFVLSILGDSPVLLLDEPSTG----IDPTG-QHQMWQAIQMS
VKNTDRAVLLVTHYLAEAEALCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKRI-FGKDYILELKVKELSQVPLV
HTAILKIFPQAA--QQERYSSC--LTYKLPIGDVYPLSQAFHKLEEVKHGFSLE---DYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELGNVD-EEVDT-TMRWKLLPHSDEP---------------------
ENSMFAP00000034471 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTFFQGYNIPLW-
---KE-----EDFSA----------------HCWDG---YG-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ISKNLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------VITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERRYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLREH---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FK-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMHLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAM
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMLN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTA-LI--SNFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEMRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFIFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTAREHLEVYAAVKGLRKVDAR-----LAITR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSPTRP00000069214 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRCMSVGQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDTPQMSSM--DLGRVDS--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAV---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEITTNHSVMEQLMSVTGVHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFPALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSQNLYLIIATLFMLVFDTLLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPAE---YGHRCSP
LFFLKSCFWFQHGRA-NHVV--LENETDSDPT-PNDCFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------C-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSRMADI
ENISK-FTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVQELEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRICNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSIT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVLSSFH--
----ETRKT-I-----------------------SGVALWRQQVCAIAKV---------R
FLKLKKE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-TIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSIACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSEH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPMAA
SFTPYIAMSSIGDYKKKA-HSQLWISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----VIFSIVATDL---NEYGF-IGLFFGTMLIPPF---
--TLI--------GSLLIFSEIS----------PDS------MDYLGASESEIVYLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-MNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTVNAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GE----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAM-----IAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQMEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDLE-EDFDP-SVKWKLLLQEEP----------------------
ENSPTRP00000044984 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRKISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
VYTPVTN------TTQQIMNKVASIPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVTFTNTY-SY----HLKFLLGHGMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCLISFSSFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTQFIILSGFMVVFSLFLLYG
LSLVALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFCGC--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLVHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRPP
LFFLKSSFWSQTQKT-DHVA--LEDEMDADPS-FHDSFERVPPEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2398)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLIYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKHE-IKALLALLLILMAGFCPLLVEYIMVKIYQN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIQSVEHQNIALEVDAFG----TRNG-TDD
PF12698 // ENSGT00760000118965_1_Domain_4 (2398, 2714)
PSY
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSVH--IRTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNFEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NIFES-DIPFIFTFLIPPA---
--TMI--------
ENSGT00760000118965_1_Linker_4_5 (2714, 2873)
GCLFLSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFTLRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYAGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSG-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDP-SVKWKLLPQEEP----------------------
ENSETEP00000005005 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHKKKKSVCQQTRALLYKNVLKKWR-----MKR
LSLLXXXXX-XXXXXXXX--XXX---XXXXXXXXXXXXXX--XXXXXXX--XXXX-X-XX
X-XXXXX------XXXX--XXXXXXXXX------------------------------XX
XX--XXXXXXXXXX--XXXXX-----XXXXXXXXXXXXX-XX----XXXXXXXXXXXXX-
---XX-----XXXXX-----------XXXXXXXXXX---XX-XXXX-------XXXXX--
XXXXXXXXXXXXXXXXXXITTNHSVMDQLMSVTGINMKVLPF---------LSKSLFQ--
NETFMLYCLIYFSPFIYFASLNV-----------TKERKRLKDLMKTMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWALTY-AGFIFIISMLIAI----------VITATKTIVMTGFVVIFTLFFLFG
LSLITLVFLTSV----------------------------LLKKSSLT---SLAV-----
LL-LTLFWGC--------VGFTVLHKQIPASLVWILSIFSPFAFTAGMAQXXXXXXX---
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXG---NERRHAL
LFFLNSSNCIQQPRI-DR-A--IEKEIDPEHS-PDDCFEPVAPEFQGKEAIRIRNIKKEY
-------------KK-------------------------------------SKVQAL--
--K--GLFFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGSGKSALLNILSGLSVPTE--GSVTIYNRNLSDMAEL
EEVQK-ITGVCPQF--NVQIDMLTVKE-NLRLFAKIKGIQPQEVE-PEVQRILLELDMQN
IQDSIAQNLSEGQKR-KLTFGIAILGDPRI--LLLDEPTAGLDPFSRHQVWNFLKER---
---------------KSDHLILLSTSFTDEAD----------------------------
--------------------I---------------------------LADRKMVLSNGR
LICAGS--SLFLK---RRWGL---GYHL--SLHRN-E----------------------M
CDPGEI-TSFLKHH--------------------IPEANL--K-TESQD-KLVYT--LPV
ER--TSVFPXXXXXXXXXXXX---------XXXXX--XXXXX----XXXXXXXXXXXX-X
XXXXXFEQ--------------A-EV--E--------GDPGNHQEVD----PAGSAPP--
----EMQNLAK-----------------------SGMALWRLQVCAIARL---------Q
FLKLKHG-KRTLLTLLALLGIAMLPLTVENLLIAVLNQ-NGHLEFKPELYFLSPGQIS--
KEPLTSLLII-----NNTGS---NIEDFIHSLKRQNILLEVDDFR----NKNG-TQDLSY
N-GVIIVSGKR-KXXX---XXXXXXXXXXXCYP-LL-MNIVSNGLLGM-N----------
----------HTES--IRIERDSLEWM-------------LIEPLTELPESLVFIFLVAC
SVAPYIAMNSVSDHKT-RAHSQLWTSG-LYPSAYWCGQ-ALVDITLY-------------
---LLILISMFV---LDN----MIP------SITNLIVFALVITTIGYAASLVFLTYTIS
FIFHKRRKNNIVLSFCFY---------VSIFLTTIIF-HWFGI-MIFIIPMILVPPA---
--TL--------NGFILFIEEQ-----------HYMY----DHRDTDFDLSAADFLVCLI
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXX-XXXXXXXXXXXX----XXXXXXX
XXXXXXXATAL-TTNLE--EKPVILASCLHKEYGATKKCCFSKKK--KKIAARNISFCVK
E
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEILGLLGPNGAGKSSCARMISGVTKPTSGKVE-LK--GSSPVW-------------GH
LGYCPQENPLWPNLTIREHLEVYTAVKGLKGGDAS-----AAITR----VVDAFKLKKML
DVPVEKLTAGTS---RMLSLALSILGNSPVLLLDEPSTN----LDPTM-QQEMWQMIQAA
VKSSRKGALLITHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGPIEHLRSK-FGKDYILEIKMKEPSQVTXX
XXXXXXXXXXXX--XXXXSLSF--LTYKLPLADVQPLSQAFHRLEA--------------
------------------------------------------------------------
---------------------------------------------------
ENSMNEP00000021978 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YYEVVGVIFRDTF-SY----QLKFNWGYRIPSI-
---KE----HTENTE----------------HCWAM---HGEI-FC-------YLAKY--
WLN
PF12698 // ENSGT00760000118965_1_Domain_0 (784, 1542)
GFVAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFLFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFRTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFIAGMAQITYLDNY---
------LSGVIFPDPSGDSYIMIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVRKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITAV
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQAKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2415)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEENLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GVSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVIRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KD
PF12698 // ENSGT00760000118965_1_Domain_4 (2415, 2770)
YR---FSVACNTKKLNCFP-VL-MGIV-NALIGIFN----------
----------FTEL--IQTESTSFSRDDI-------------VLDLGFIDGSVFLLLITN
CISPFIGMSSINDYKKKV-QSQLWISD-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWELVFVLAVCIIGCAASLIFLTYVLS
FIFRKWK-KNGFWSFGFFII-----LICVSTIL-VS--TQYET-PNLILCMIFIPSF---
--TLL--------GYIMFLIQFS----------LMYMRNLDSLDSRINEVNKTILLTTLI
PYLQSLIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLT--EEPVITASCLHKEYYDRKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RSVSFCVR
KGEVLGLLGHNGAGKSTSIKMITGYTKPCAGVVV-LQ--DSRT-LVRQQHDN----SLKF
LGNCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KVPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVKAL
HTEILKLFPQAA--RQERYSSF--MAYKLPVKDVHPLSRAFFKLEAVKQTFNLE---EYS
F-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSRROP00000034365 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDI----------YHQMVGVIFRDTF-SY----QLKFNWGYRIPII-
---KE----HSEYTE----------------HCWAM---HGEI-FC-------YLAKY--
WL
PF12698 // ENSGT00760000118965_1_Domain_0 (783, 1542)
HGFVAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------LSKGEIM--
NEWFLFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FAVFWGC--------LGFTVLHRQLPLSLGWVLSLFSPFAFIAGMAQITHLDHY---
------LRGVIFPGPSGDSYIMIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFRKSSFWSKHQ-NTHHEI--FENEINSENS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHDGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITDM
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVK-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPTAGLDPFLRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTEICLWK------KR
TN--FQVTYYLYSDLDKCSDQ---------GIRNY--ATA-P----GLNEVFLNLEGK-S
AIDEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVLRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGE-KREFR--------------------------------
---TYICVLFF-KDYR---FSVACNTKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSRDDI-------------VLDFGFIDGSIFLLLITN
CISPFIGMSSISDYKKKV-QPQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWERTFVLVVCIIGCAASLIFLTHVLS
FIFHKWRKNNGFWSFDFFII-----LICVTTIL-VS--TQYEN-LNLILFMIFIPSF---
--TLL--------GYVILLIQLD----------FMYMTNLDSLDSRINEVNKTILLTTLI
PYLQSVVFLFVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLA--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAIR-------
PF00005 // ENSGT00760000118965_1_Domain_5 (2881, 3037)

-GEVLGLLGHNGAGKSTSIKMIAGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPQENSLWPTLTMKEHLELYAAVKGLDKDDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMVSGML---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPSQVEAL
HTEILKLFPQAA--RQERYSSL--MAYKLPVEDVHPLSWAFFKLEAVKQTFNLE---EYS
L-SQATLAQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSPPAP00000034448 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRKISMCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
VYTPVTN------TTQQIMNKVASTPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVTFTNTY-SY----HLKFLLGHGMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCLISFSSFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTQFIILSGFMVVFSLFLLYG
LSLVALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGC--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLVHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRPP
LFFLKSSFWSQTQKT-DHVA--LEDEMDADPS-FHDSFEQVPPEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2398)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLIYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKHE-RKALLALLLILMAGFCPLLVEYIMVKIYQN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIQSVEHQNIALEVDAFG----TRNG-TDD
PF12698 // ENSGT00760000118965_1_Domain_4 (2398, 2714)
PSY
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSVH--IRTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LFPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNFEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NIFES-DIPFIFTFLIPPA---
--TMI--------
ENSGT00760000118965_1_Linker_4_5 (2714, 2873)
GCLFLSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFTLRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYAGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSG-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDP-SVKWKLLPQEEP----------------------
ENSETEP00000001263 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MGKMVWSVIK------------------------------XX
XX--XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX-XX----XXXXXXXXXXXXX-
---XX----X-XXXX----------------XXXXX---XX-XXXX-------XXXXX--
XXXXXXXXXXXXXXXXXXIATNHSVMEKLLSVTGINMRTLPF---------ITKSKAI--
NELVMFTSIMSFSPFVYFLSLNI-----------TKERKRLKKLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMSTIWA-------L---VLTSFQFIVLTGFMVTFTLFALYG
LSLIASVFLL-----------------------GVL-----IKKPVLT---GLTT-----
FL-FTIFW-GC-------LGFTVLHRTLPSALEWTLGLFSPFAFTAGLSKXXXXXXX---
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXE---NGHRHPP
LFFLKSSFGSHLQNT-PHEV--LEDEINPEHL-SDDAFEPVPPEFNGKEAIRIRNVKKEY
-------------NGK------P-----------------------------GKIQAL--
--R--GICFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1852)
GQVTAILGHSGAGKSTLLNILSGLSVSTE--GSATIYNTKLSQSANM
EDIRK-NLGFCPQF--NIQFDFLTVRE-NLRLFAKIKGIQPKEVE-QEVKRIIMELDIQN
IQNVFAKELSGGQKR-KLTFGITLLGDPXX--XXXXXXXXXXXXXXXXXXXXXXXXX---
---------------XXXXXXXXXXXXXXXXX----------------------------
--------------------X---------------------------XXXXXXXXXXXX
XXCAGS--SLFLK---QKWGI---GYHL--SLHRN-E----------------------T
CDPQRI-TSLVKQH--------------------IPEAKL----RAESEEKLVYT--LPL
GN--TDKFPDLYNDLDKCSG---------QGITSY--GVSMT----TLNEVFLNLEGI-S
TID--E--PDFG-----IK-QEA-XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXX--
----XX-XX-------------------------XX--X---X--XXXXX---------X
XXXXXXX-XXXXXXXLLLFCMGFIPIVLENIVYKIYEP-NQFWEYLPSKYFLSLEQLP--
RAPLTSLLII-----ND--TGS-NIEDLVNSIEHQNITLEVDDFR----NRNG-SDDPSY
N-GAIIVSG---DEKDYK-FSVACHTKRLNCFP-VL-MGIVSNALLGIFN----------
----------STGH--IETKGRSFIHDD-------------LRIGIGLLNWSILLMFFAN
GMSPNIGMSSISDY---------KVSG-LYPSAYWCGQ-ALVDIPLY-------------
---YVILLSAFL---IQYFMVA-DF------IILNKYMIAAVVCLFGCAASIILFTYVVS
FIFHKGRENTGLWSLVFFII-----SIMTFFIMVY---DGFRM-TTIILCMIFIPLS---
--TSL--------GFIVYLILS------------SSIPTMGEGNE-NYEAVKTMVATVLI
AFLQSLLFLLLLRCLE-MKYGSETRRKDPVF-RISPRTRDPQPNPEAPE----DEDEDVQ
AERVNTANALT-APNVD--EKPVIMASCLHKEYKRKKKSCFSTRT--KKIAIRNVSFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEILGLLGHNGAGKSTSIKVIMGDTKPTAGVVV-LQ--GNPPSAR-PQA-D----SIRF
LGYCPQENTLWPSLTMQDHLELFAAVKGQDKEEAA-----LSISR----LVNMFKLQDQL
KVPVKTLSEGIK---RKLFVLT-VXXXXXXXXXXXXXXX----XXXXX-XXXXXQAIQST
VRNKERGVLLSTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKNYLLEVEMKR------V
HVEILKLFPQAA--RQERYSSL--MAYKLPVDDVHPLSQAFFKLEAVKQTFDLE---EYS
L-SQATLEQV----------------------------------------------FLEL
SKEQELGNFD-DEIDA-SVKWKLLPQEEP----------------------
ENSMFAP00000033729 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEVVGVIFRDTF-SY----QLKFNWGYRIPAI-
---KE----HTENTE----------------HCWAM---HGEI-FC-------YLAKY--
WLNGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFLFTCLVSFSSFICFASLNV-----------A--RGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFIAGMAQITYLDNY---
------LS---------------ATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVRKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITAV
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2513)
AGLDPFS-----SLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEENLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GVSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATF---------R
FLKLRHE-RRVLLCLSLVLGVAFIPIILEKIMYKVIRE-THCWEFSPSMYFLSLEQIL--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSHDDI-------------VLDLGFIDGS
PF12698 // ENSGT00760000118965_1_Domain_4 (2513, 2770)
VFLLLITN
CISPFIGMSSINDYKKKV-QSQLWISD-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWELVFVLVVCIIGCAASLIFLTYVLS
FIFRKWRKKNGFWSFGFFII-----LICVSTIL-VS--TQYET-PNLILCMIFIPSF---
--TLL--------GYIMFLIQFS----------LMYMRNLDSLDSRINEVNKTILLTTLI
PYLQSLIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLT--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKMITGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KVPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVKAL
HTEILKLFPQAA--RQERYSSF--MAYKLPVEDVHPLSRAFFKLEAVKQTFNLE---EYS
F-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSCGRP00001027759 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRVGQQTWALFCKNWLKKCR-----MRR
ETVME
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WFFS-LLLVFFAY-LLSF---NLHQVHDAPQIPEM--DLGRVDN--FNDS-NYII
AFAPESK------TIYEIMSIVASTPFM------------------------------KG
RR--IVACPDETSMNELDLNY-----SMDAVRVIFKDTF-SY----HLKFPWGHRIPPV-
---KE----HKDHSA----------------PCETV---N-NTITC-------RNSVF--
WEKGFVAFQAAINAGIIEMTTHHSVMEELMSVIGVNMKILPF---------IAQGGVT--
TDFLIFFCVISFSPFIYYLSVNI-----------TQERQYITILMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILVVATLMSL----------IVKSAQIVVLTGFMVVFLLFLLYG
LSLITLAFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTIFWGS--------LGFTALYKHLPAFMEWTLCFLSPFAFTAGMAQLIHLDYD---
------VNSNVNLDSPNNSYLIIATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDRVLLSK---YGHRRSP
LFFLKSSYWFQHRGA-NHVV--LENEIDSDPS-LNDSFEPVPPEFQEKEAIRIKNLKKEY
------------A-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINILCGLSPPTT--GSITIYNQTLSEVDDF
DAVIK-LTGVCPQS--NIQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQRVLQDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2440)
AGLDPFSRHCIWNLLKER---
---------------KLDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPESI-TSLVKKH--------------------IPDARL----TTQSEERLMYI--LPL
ES--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
MTDES---------GVGIS-GHL-QSEGA--------KDMGSLVELE----QVLLSLD--
----SSGNT-V-----------------------SGMALWRQQLCAVAKV---------R
FLKLKNE-RKSLMTMLLLFGISFLPQLLEHLFYELYHK-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-SIDKFVHSLRQQSIALDVDVLG----TRNG-REEALY
N-GAITVLGDE-KDLR---FSIACNTKRLNCFP-VL-MD
PF12698 // ENSGT00760000118965_1_Domain_4 (2440, 2719)
IISNGLLGIFN----------
----------SSQR--IQTERSTFFEEQML-------Y-ESGYV-----SNA-LWVPLAA
SLAPYVAMSSISDYKKKI-LSQLWVSG-LYPSAYWCGQ-ALVDIPLY-------------
---FLILLLMQI---MECVFSQEEI-----IFIMENLL-IQVLCSIGYASSLVFLTYIIS
FIFRNGRKNSGIWSFFFLIV-----TIFSLVATDI---NERGL-LGLLLCTFLIPPF---
--TLI--------GSLLI
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
FSEIS----------YDS------VDSSGASDSQVEFLALLI
PYFHFLLFFFVLRCLE-RYFRKKSLRMDPVF-RISPRSCNAFPNPEDPGE----EDEDVQ
MERIRTADSVT-ALQID--EKPVIIASCLRKEYTGKKKKCFSKAK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTKPTAGQVF-LK--GCGE-------DA----ALGF
LGYCPQENVLWPILTVKDHLEAYAAVKGLKKKDAL-----VTVTR----LVNALKLQDQL
KAPVKTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAS
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAQVEPL
NMEIMKLFPQAA--RQERYSSL--MVYKLPVEDVWPLSQAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDS-SVKWKLLPQEEL----------------------
ENSMMUP00000045716 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------ESSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQEKQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPHLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHMLSGMADV
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVQDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2392)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRYSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVFSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRQQNIAIEVDAFG----TR
PF12698 // ENSGT00760000118965_1_Domain_4 (2392, 2771)
NG-TDDPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------ED----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFEP-SVKWKLIPQEEP----------------------
ENSVPAP00000003190 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDKMALAAFM------------------------------KG
RT--VIGTADEEAMNRVPPEH-----SSEVVGVVFSDTF-SY----QLKFSQRYRFPII-
---KE----HFEHSE----------------HCRGL---PDEV-YC-------SLTSY--
WKKGFVAFQTAINAAIIEXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXX--
XXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWALMY-AGFIFIMSILMVL----------VIKFVQIIVIPGFMVIFTLFFLYG
LSLIALAFLLSV----------------------------LIKKPFLS---SLVG-----
FL-FTVFWGG--------LGFFVLYRQLPLSLAWALGLFSPFAFTAGMAQISHLDYN---
------LSGVVFPDPSGESHIMIVMYFILVFDTLLYLILTLYFERVLPDE---DGHRHSP
LFFLKSSFWSQHQ-NTHHEV--FENEMNPEDS-SEGSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------P-----------------------------EKVEAL--
--Q--GIFLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVCTE--GSTTIYNTQLSEITKM
EEIRK-DIGFCPQF--NIQFDFLTVRE-NLRLFAKIKGIQPKEVE-QEVKRVIMELDIEN
FQDVIAKKLSGGQKR-KLTFGIALLGDPQI--LLLDEPTAGLDPFSRHRVWSFLKEC---
---------------KTNHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CNLDRI-TSLITQH--------------------ISDAKL----TAESKEKLVYS--LPL
ER--TNKFPDLFRDLEKSSDQ---------GIMNY--GISMT----TLNEVYLNLKGR-S
AIDEP---------DLGIQ-KQG-EICVT--------RGTEIESEMG----QALCSLP--
----EMKKA-I-----------------------NSGTLWRRQICAMARL---------R
FLKLRRE-RKILLSLLVVFGIVLIPVICEKIMVVVLHH-THRWEFSSSMYFLSSEQLP--
QTPLTSLLII-----NN--TGS-NIEDLVQSLKRQDIVLEVDDFR----NRNG-SDDPSY
N-GAIIVSGDH-KDYR---FSVACHTKRLNCFP-VL-MGIISNALLGIFN----------
----------FTEL--IKTERSIFPSDDV-------------ILILGSLD--LLLLLLVN
CASPYIGMSSISDYKQKV-QCQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FMIVLPIHL---IYCFMFL----EF---TFPLGFLFALMVCIAVCAASSMFFTYIIS
FIFPTGRKNKGFWSLGFLMI-----SIFIAIIL-ES--TSTGN-TTLIICMILMPSF---
--TF----------LFVYLIQLS----------FMYKRSSESQNFGNTVADYFVLLAILI
PFLQSIIFLFVIRCLE-MKYGKETMRKDPVF-XXXXXXXXXXXXXXXXXX----XXXXXX
XXXXXXXXXXX-XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX
X
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
XEVLGLLGHNGAGKSTSIKMITGETEPTAGVVI-FH--GSST-SLKQ-QDD----ILKF
LGYCPQENALWPDLTVKEHLELFAAVKGLGKEDAA-----LHISG----LVDALKLQEQL
KLPVKALPEEVK---RKLCFALSLLGNPSVVLLDEPSTG----MDPEG-QLQMWQAIRAI
VRNTERGALLATHYMAEAEAVCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKNK-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX--XXXXFSSV--MAYKLPVKDVRPLSQAFSKLEAVKQTFDVE---EYS
L-SQATLEQV----------------------------------------------FLEL
SKEQELGNFD-DEVDT-TVRWKLLPKEEP----------------------
ENSNGAP00000008993 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRKISVCQQTWALFQKNVLKKWR-----MKR
EFLMEWINS-LLLLLFLY--LYP---NGHQVTDFSSLPTM--DLGRVDS--FTTS-KFLI
AYSPVTS------TTQQIMKKVADVSFM----------------------------TG-E
KE--VLGLSDEESIKEVTANH-----PDEVIRVIFSDTY-SY----HMKFLLGQRIPIR-
---KE----HRDHAA----------------PCFET---F-EDTDC-------LVSKF--
WKSGFMALQAAINAAIIEVKHEIL------------------------------------
----RVFC----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-FCTR
PF12698 // ENSGT00760000118965_1_Domain_1 (1326, 1541)
LSWGLLY-AGFVFIMALFLAL----------VIKSVQFFVLSSFAVVFTLFLFYG
LSMIALAFLMSV----------------------------LIKKSFLT---GLMV-----
FF-LTVFWGS--------VGFTAVYRYLPASVEWILSLFSPFAFTLGMAQLLHLDYD---
------LNSNAPPDPAGGSNLIIITNFMLAFDTVLYLVLM
ENSGT00760000118965_1_Linker_1_3 (1541, 1682)
MYLEKILPNE---RGLRHSP
LFFLKPSFWSQQRVP-DPVV--LEDEIDSDLS-SNDSFEPMPPEFHGKESIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDIYEGQITAILGHSGAGKSTLLNILSGLSVSTK--GSVTIYNNKLSEMSDL
ENIVS-ITGVCPQS--NVHFDFLTVRE-NLRLFAKIRGIPSQEVK-KEVQKVLLELEMKN
IQNVLVQNLSGGQKR-KLTFGIAILGDSQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2366)
AGLDPFSRHQVWSLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LAGNGWMLRD--
------------------------------LRTLN-E----------------------I
CVRENI-TSLVKQH--------------------IPEAKL----SAESEGKLVYM--LPL
ET--TYRFPELYKDLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TTDEP---------ETDIL-GEG-QEDRV--------EDTERLIEME----QIFSSLT--
----EMKKT-I-----------------------DGVALWGQQICAIAKV---------R
LLKLKHE-RKALLSLLLILAVGFFPLLLEYILVKIHQN-SYTWELSPHSYFLAPGQQP--
QDPLTQLLII-----NK--TGA-SI
PF12698 // ENSGT00760000118965_1_Domain_4 (2366, 2770)
EDFIHSVEHQNIALEVDASG----ARDG-VDNPSY
N-GAITVSGSR-KNYS---FSFACNAKRLNCFP-VL-LDIVSNGLLRMVK----------
----------PSAR--IQTDRSTYLEGSQ--------F---EYL-----GHTMFWLVLAS
SCPPYIAMSSVSDYKIKA-WSQLRISG-LFPSAYWLGQ-ALVDAPLY-------------
---CLVFIFMYL---MDYLFSFQET-----VFTVINRI-IIGK-E---------------
-------MGHGI---------------FEINHLDLE--TRNEI-KSMYCVIFLIPQA---
--TLV--------GCLFLSFHLL----------IF------RIFNEE-PKSSEPFLVFLI
PFLHVFIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FTLRCLE-WKFGKKSMRKDPFF-RISPRSNDVCQNPEEPEG----EDEDVH
MERVRTASALS-STNFD--ERPVIVASCLRKEYAGKRKRCFSKKK--PKVAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3033)
RNISFCVR
KGEILGLLGHNGAGKSTSIRMITGDTKSTAGQVL-LK--GTRE-------GD----TLGF
LGYCPQENVLWPNLTVKEHLEVFAAVKGLNKSDTA-----VTIMR----LVDALKLRDQL
KSPVKTLSEGLK---RKLCFVLSILGNPSVVFLELSKEQELDGFEEELDSSVKWKLLPQ-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------EEA----------------------
ENSCGRP00000022735 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRVGQQTWALFCKNWLKKCR-----MRR
ETVME
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WFFS-LLLVFFAY-LLSF---NLHQVHDAPQIPEM--DLGRVDN--FNDS-NYII
AFAPESK------TIYEIMSIVASTPFM------------------------------KG
RR--IVACPDETSMNELDLNY-----SMDAVRVIFKDTF-SY----HLKFPWGHRIPPV-
---KE----HKDHSA----------------PCETV---N-NTITC-------RNSVF--
WEKGFVAFQAAINAGIIEMTTHHSVMEELMSVIGVNMKILPF---------IAQGGVT--
TDFLIFFCVISFSPFIYYLSVNI-----------TQERQYITILMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILVVATLMSL----------IVKSAQIVVLTGFMVVFLLFLLYG
LSLITLAFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTIFWGS--------LGFTALYKHLPAFMEWTLCFLSPFAFTAGMAQLIHLDYD---
------VNSNVNLDSPNNSYLIIATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDRVLLSK---YGHRRSP
LFFLKSSYWFQHRGA-NHVV--LENEIDSDPS-LNDSFEPVPPEFQEKEAIRIKNLKKEY
------------A-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINILCGLSPPTT--GSITIYNQTLSEVDDF
DAVIK-LTGVCPQS--NIQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQRVLQDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPFSRHCIWNLLKER---
---------------KLDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPESI-TSLVKKH--------------------IPDARL----TTQSEERLMYI--LPL
ES--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
MTDESGDRSYS--SGVGIS-GHL-QSEGA--------KDMGSLVELE----QVLLSLD--
----SSGNT-V-----------------------SGMALWRQQLCAVAKV---------R
FLKLKNE-RKSLMTMLLLFGISFLPQLLEHLFYELYHK-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-SIDKFVHSLRQQSIALDVDVLG----TRNG-REEALY
N-GAITVLGDE-KDLR---FSIACNTKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2719)
-VL-MDIISNGLLGIFN----------
----------SSQR--IQTERSTFFEEQML-------Y-ESGYV-----SNA-LWVPLAA
SLAPYVAMSSISDYKKKI-LSQLWVSG-LYPSAYWCGQ-ALVDIPLY-------------
---FLILLLMQI---MECVFSQEEI-----IFIMENLL-IQVLCSIGYASSLVFLTYIIS
FIFRNGRKNSGIWSFFFLIV-----TIFSLVATDI---NERGL-LGLLLCTFLIPPF---
--TLI--------GSLLI
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
FSEIS----------YDS------VDSSGASDSQVEFLALLI
PYFHFLLFFFVLRCLE-RYFRKKSLRMDPVF-RISPRSCNAFPNPEDPGE----EDEDVQ
MERIRTADSVT-ALQID--EKPVIIASCLRKEYTGKKKKCFSKAK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTKPTAGQVF-LK--GCGE-------DA----ALGF
LGYCPQENVLWPILTVKDHLEAYAAVKGLKKKDAL-----VTVTR----LVNALKLQDQL
KAPVKTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAS
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAQVEPL
NMEIMKLFPQAA--RQERYSSL--MVYKLPVEDVWPLSQAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDS-SVKWKLLPQEEL----------------------
ENSETEP00000000297 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------SF----YCKRPQ----SKMSERKISVCQQAWALLYKNCLKKWR-----MKR
DSLMEFLNA-FILLLSLY--LL-P--NIHHVNDFSSLPIV--DLGRVDS--FEVS-NFIV
AYTPITS------RTQQIMSKLAIAPFM------------------------------KD
GK--ILGVSDEEQMEELSENY-----SDEIIKVIFTNTF-SY----HLKFLLGHRIPTR-
---KE----HRDHTA----------------HCYEM---NE-DIEC-------GLAEF--
WSKGFVAFQAAINAAIIETTTNHSVMDELMSATGKIMKIHSF---------ISQGGLL--
TDFIIFFCIISFSPFTYYASLNV-----------TRERKKMKGLMKLMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGSLY-AVLIFIMALFMAL----------IIKSSQFVILTGFVVVFNIFLLYG
LSLVALVFLMSV----------------------------WVKKPFLT---GLVV-----
FM-LT-VLGS--------LGFTALYRHLPASLEWTLSIFSPFAFTLGMAQ----------
-------------------------------------ALMVYLEKVLPNE---YGHQRSP
LFFLKPSFWSRQQKD-VHVP--FEDELDFHPS-SNNSFEPVCMEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------NNIEAL--
--K--DLTFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNTKLSGSTDF
ENTNK-LTGICPQS--NVQFDFLTVKE-NLRLFAKIKGIQPQEVE-KE------------
-----------------------------I--FLLDEPTAGLDPFSRHRVWNLLKER---
---------------KKDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQVN-E----------------------M
CVREKV-TAFIKQH--------------------IPDAKL----SAESGGKLTYT--LPL
ER--TNKFPELYRALDSSPDL---------GIEDY--GVSMT----TLNEVFLKLEGK-S
AIDESDVD---------LS-EEG-QAEGG--------GDTERLIAME----QALSSVN--
----EI-NNTV-----------------------RGMALWGKQVCAIAKV---------R
LLKLKHE-RRALLTLLLILGVGFSPTLLEYVITKVYYN-SYTWELSPHTYFLAPGQQP--
HEPLTRLLII-----NK--TGA-SIDDFMQSVERQNLALEVDGSG----TREG-TDDPSY
N-GAITVSGNK-VKYNFS-L--ACNAKRLNCFP-VL-MDIVSNALLGMFQP---------
-----------SAH--IQTDRSTFFVEE-------------RDNPFALISHSMFWLILAA
SCSPYIAMSSVDDYKX-XXXXXXXXXX-XXXXXXXXXX-XXXXXXXX-------------
---XXXXXXXXX---XXXXXXXXXX------X-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXI-----IMFSVMIFML---GNDGK-TALLCITFLVPPA---
--TLI--------GCLFLSVHX------------XXXXXXX-XX----XXXXXXXXXXXX
PFLHFIIFLFILRCLE-WKFGKKTMRKDPVF-RISPRSNDVCQNPEVPE----GEDEDVQ
LERARTANALN-STNFD--EKPAIIASCLRKEYAGERERCFSKKK--KKIATRNVSFCVR
KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--XXX-------XXX----XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX----XXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------
---------------------------XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX--XXXXYSSL--LVYKLPVDDIRPLSQAFFKLETVKQNFDLE---EYS
L-SQSTLEQ---------------------------------------------------
---------------------------------------------------
ENSCGRP00001027182 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVNREINVCQQTWALLCKNLLRKRR-----MKR
DTFLEFLYT-SIILFSLS--LTT---EIHEVYDFSHLPNV--DLGR
PF12698 // ENSGT00760000118965_1_Domain_0 (587, 1542)
IDS--FNDS-NFMI
AYTPVTH------TTQGIMDKVSLASYM----------------------------A--G
IT--VLGFPDEENMTELVSSR-----YHDVVRVIFTNTY-SY----HLKFHTGTRMPSK-
---KE----HGDHTA----------------HCSTY---E-DNINC-------GISHF--
WTEGFVALQAAINSAIIEVTTNHSVVEEMMSVTGKYMKIDTF---------IGQGGVV--
TDSFLVFCIICFSPLAYYISAGV-----------TRERKKMKGLMTVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GAIIFVVSLLLTF----------IIKLVQFVILTGFMAIFSLFFFYG
LSLISLSFLMSV----------------------------LLRKSFLT---DFVV-----
FF-LTVFCGS--------LGFAALYRILPGSLEWVLSLLSPFAFMLGMAQLLHLDYD---
------VNSNA--DPTGNPNVIIATIFMLFFDSVFYLVLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSE---YGQRHSP
LFFLKPSFWSQQNQVLDY-------EIDSE-F-LDDSFEPVSSDFHGQEAIRIRNLTKEY
-------------TER------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-A--DLSLDIYKGQITAILGHSGAGKSTLLNILSGLCAPTK--GWVTIYNNKLSEKTDL
ESIIK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIRKHEVD-NEVQRVLMELEMKN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2503)
AGLDPFTRHRVWNLLKER---
---------------KAGRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CVPERI-TSLIKQH--------------------IPDSKL----SAESEGKLSYI--LPL
ER--TNKFPDLCRDLERCPDL---------GIENC--GVSIT----TLSEVFLKLEGK-S
TIDQS---------DLGMS-EDV-QTERT--------RGTGRPTEME----QLVSLLT--
----EKTNM-K-----------------------VGLALWWQQLCAVARL---------R
FRKLKHE-RKSFVFLILILGIGLLHILSANIGMIARVS-DYCWELSPHMYFLTPGQQP--
HEPLTNLLII-----NK--TGA-QIDDFIHSLEKQNISLEIDAFG----TRNG-TEETLY
N-GAIILSGGE-NSFK---FTLACHTKRLNCFP-VL-VDIVSNGLLGLFT----------
----------PSAH--IQTDRSTFPEDDT---RG--PF---D
PF12698 // ENSGT00760000118965_1_Domain_4 (2503, 2703)
YV-----PYFISWILFMA
FVPPYISMTSIDDYKNGV-QLQLWISG-LCPSAYWFGQ-ALVEVPIY-------------
---YILSLSMCV---AFYASAPQET-----MLTTKDLL-FQILYVGGYAMSIIFMTYVIS
FLFRKGRKNSGIWSFCFYIV-----ALCSILLI-FT--DYFLD-DLLFCIIALIPPA---
--
ENSGT00760000118965_1_Linker_4_5 (2703, 2873)
TLV--------GCTMLHFQYC----------A-----LCDIG-LEEATSDYTFLLFLV
SFLHFAIFLVILRCLE-SKLGMKTMRMDPVF-RISPRTDRVFNNPEEPEG----EDEDVR
LERERTANALT-SVDFQ--EKPAIIASCLRKEYKGKKKCFVPKSK--KKLAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKIITGEAKPSAGQVL-MK--GSSR-------GD----TLGF
LGYCPQENALWPNLLVREHLEIFAAVKGMSKGDAA-----VAIAR----LADALKLQDQM
RAPVKTLSEGVK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVRIPAQVEAL
NAEIKRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDCFE-DELDP-SVQWKLLPQEEA----------------------
ENSFCAP00000014537 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHISVGQQTCALLCKNFLKKWR-----MKR
ETLLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WFFS-FLLVLFAY-RLSS---NLHQVNDFPQLPAM--DLGRVDH--FNDS-NYVI
AFAPESK------TTQEIMNKVASAPFM------------------------------KG
RP--ITGWPNENGMKELDLNY-----SVDAVRVIFNDTF-SY----HLKFFWGSRIPKM-
---KE----HRDHSA----------------HCQVT---E-GKTTC-------EGSMF--
WEKGFVAFQAAINAAIIEITTNRSVMEELMSITGINMKILPF---------VAQAGVA--
TDFFIFFCIISFSAFIYYVSVNV-----------TQERQYIKSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLCWGLMY-GGFNFIVATLMAL----------IVTSAQVVVQTGFVVIFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRDLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNVHLDSSDNPYLIIATLFMLLFDALLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPSE---YGHRRSP
WFFLKSSFWFLHQRA-DHVA--LENETDSDSSPPNDSFEPVSPEFHGKEAIRIRNLKKEY
------------RKGN------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVFDIYEGQITALLGHSGAGKTTLLNTLSGLSSPTS--GSVTIYNHSLSEMADS
ETISK-LTGVCPQT--NVQFGFLTVRE-NLRLFAKIKGIQPHEVE-QEVQQVLRDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGNPQV--LLLDEPTAGSDPLSRHRIWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDRI-TSLVKQH--------------------IPEAKL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCSNR---------GIEDY--GVSMT----TLNEVFLKLEGK-S
AVGES---------DTGIW-GEL-QSPGT--------KDTGSLVELE----QALSSFN--
----ETKKL-I-----------------------SGVALWRQQLCAIAKV---------R
LLKLKSE-KKTLLTILLLFGISFCPQLLEHLFYEFYQK-SYSWGLAPNMYFLSPGQPP--
QVPLTPLLVI-----NK--TGS-SIDNFVRSLRQQNIALEVDAFG----TRNG-PNEPSY
N-GAITVSGDD-KGHR---FSIACNTKRLNCFP-VL-MDIISNGLLGIFN----------
----------SSER--IQTDRSTYFEEHVS-------Y-DHEYL-----SNAFFWIPVAA
CFTPYIAMSSISDYKSKA-HSQLRISG-LYPSAYWFGQ-ALVDISLY-------------
---FLILLLMQI---MDYVFSPDEI-----VFVIQNLL-VQ-------------------
-------------------I-----TIFSIVATDL---NEYGF-LGLFLCTILIPPF---
--TLI--------GSLFIFSEVT----------LIL------L--------FLWRFLILI
PYLHFCIFVFVLRCLE-MKFRKKLMRKDPVF-RISPRGSDICPNPEEPEG----EDKDVQ
MERMRTTNAVT-VADFE--EKPVIIASCLRKEYAGKKRNCFAKRK--KKVAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGFLGHNGAGKSTTIKMITGDTNPTSGQVV-LK--GSGE-------GA----SLGF
LGYCPQENVLWPNLSMREHLEVFAAIRGLKKGDAT-----VTITR----LADVLKLQDQL
KLPVRTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQHMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPTQVKPL
HCEILRLFPQAA--RQERYSSL--MVYRLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVRWKLLPQEDP----------------------
ENSTSYP00000028696 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MKKREISVCQQTWALLCKNFLKKWR-----MKR
ESLLEWMNS-L
PF12698 // ENSGT00760000118965_1_Domain_0 (552, 1542)
FLLLFLY--IYP---HRHQVNDFSSLPTM--DLGRVDS--FNES-GFSI
AYTPVTN------TTQQIMNKVASASFL----------------------------A--G
KE--VLEFPDEESIKEFTANY-----VGEIVRVIFTNTY-SY----HLKFLLGHRIPTR-
---KE----HRDHTA----------------HCYGT---S-EDFDC-------EVSLF--
WEEGFVALQAAINAAIIEITTNHSVKENLMSVTGKNMKIHAF---------IGQSGIV--
TDVFVFICIITFSSFTYYASANI-----------TRERKRMKGLMTMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIVIMAIFLAL----------VIKSTQFVILTGFMAVFTLFFLYG
LSVMALSFLMSV----------------------------LIKKPFLA---GLAV-----
FL-LTVFWGS--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMTQLLRLDYD---
------LNSNAFPDPSGDSNLIIATTFMLAFDTFFYLALTI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRYPP
LFFLRSSFWSRQQKA-HHVA--LD-DIDPDPS-SDDSFEPISPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--DLVFDIYEGQITVILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
EHISK-LTGVCPQS--NVQFDFLTVRE-NLMLFAKIKGILPREVD-KEIQRVLLELDMKN
IQNVLAQNLSGGQKR-KLTFGIALLGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2400)
AGLDPFSRHRVWNLLKER---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVQENI-TALVKQH--------------------IPDAKL----SAEREGKLVYT--LPL
ER--TNKFPELYMDLDSIPGL---------GIESY--SISMT----TLNEVFLKLEGK-S
VLDES---------DIAIL-GEV-QAERA--------RETESLVEME----QVISSLN--
----DIRNT-I-----------------------GGVALWRQQVCTIARV---------R
LLKLMHD-RKALLSLLLILAVGLTPFLLERIFVKIYHN-SYTWELSPHLYFLTPGQQP--
HDPLTQLLII-----NK--TGG-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPS
PF12698 // ENSGT00760000118965_1_Domain_4 (2400, 2770)
Y
N-GAILVSGNK-NNYS---FSLTCNAKRLNCFP-VL-MDIVSNGLLGMFK----------
----------PSAR--IQTDRSTFMDGLS-----NDSF---AFL-----GYTVFWLILAS
CCSPYIAMSSIEDYKNKA-WSQLRISG-LFPSAYWLGQ-ALVDVPLF-------------
---FTIFLFMYI---MDHILNFHDT-----IFAVLNHI-VQIPCAVGFSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVM-----TVFSVAGF-MI--STFET-SLQFFITFFIPPA---
--TLV--------GCLFLSFHFF----------LQ------SFNGEE-SSDMLPVLVFLI
PILHFIIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FILRCLE-WKFGKTSMRRDLFF-RISPRSSDVRQNPEEPEG----EDEDVQ
MERVRTANALN-STNSD--EKPVIIASCLRKEYAGKRKHCFSKQK--NKVAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVA-LK--GSSG-------GD----TLGF
LGYCPQENALWPSLTVREHLQVYAAVKGLRKGDAE-----VAITR----LVDAVRLQDQL
KAPAKTLPEGEK---RKLCFLLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLAHVEPL
HTEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELEDFD-EDLDP-SVKWKLLPQEEP----------------------
ENSPSIP00000010295 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MAALFQIVHLEDN---
------VKGVDFSDFLEDSYPMLALYFLLAFDALLYLTLAIYFDKVLPDK---YGTRHSR
LFFLKPSYWFKERQK-GVRSDILDHEEHSDQG-VSDHIEQVPPEFRGKEAISINNIKKTY
-------------GEK------D-----------------------------KTVKAL--
--K--GLFLNVYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLCPPSE--GSAIIYKYKVSEMEDL
KEIRK-IIGVCPQF--NVQFEVLTVKE-NLRIFAKIKGILPKEVE-QEVQKVLTMLKITD
VQDCQASSLSGGQKR-KLTLGIAILGDPQV--LLLDEPTAGLDPSSRYHVWSLLKEH---
---------------KANRVTLFCTQLMDEAD----------------------------
--------------------I---------------------------LADRKAFISHGR
LKCVGS--SLFLK---RKWGI---GYHL--SLHIN-D----------------------S
CDTVKV-TSLVKQY--------------------IPSAKL----SGQSQEELIYM--LPF
EN--VDMFPELFCDLDASACP---------GILSY--GISMT----TLTDVFLTLEEE-A
AVEEADYG---------VF-GEE-QAEEE--------RETFSADELE----QRLLSLS--
----DTSRATV-----------------------SGAALWRQQACAVARI---------R
FLKLKHE-SRTIRSILLLCGFLILPILLIKILTEKRTV-AHTLKVSPQMYFLQPGWQH-Y
QTRHTSLLVL-----ND--TGS-DIEDFIHAVKSQNIMLETANWK----N---ISDAREY
N-GAIKVSLED-KHFR---FTMMCNAQRINCFP-VL-MNIISNALLRTLN----------
----------STRH--IQIMSRTPPLV-----------RS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSAMEP00000007641 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKKEISIYQQTQALLYKNFLLQWR-----MKK
ESLLVWFSISFFLYLDVM--LME---EPFRATHLPEQPPH--ALGRMDE--FNDS-DLVV
GYTPVTN------MTQRIMDKMALASFM------------------------------KG
HGGGWCGATGEGRMDTVLSEN-----CHETVGIVFDDTF-SY----QLKFSWGYEIPNV-
---EE-----DS-----------------EEHCWDN---DD-KIFC-------YVARY--
WQYGFVAFQTAINAAIIEVTTNHSVMEKLVSVIRINMRMLPF---------ISNGEII--
NTWFTFICVSYFSSFVYFTSLNV-----------TQ----FKKLLTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSCGLMY-AGLIFILSIFMAL----------IITSIQIVVIAGFMVIFTLFVLYG
LSLIALAFLLSV----------------------------PIKKPILT---GLAG-----
FL-FT-IWGC--------LGFTAWYRQLPSSLEWTLGLFSPFAFTAGMAQILHMDYYHVY
HGTIITMIGFIFPNPSGESYVRTVTFFLLALHTLLYLILTLYFDSLIEWS---DQNCLIQ
LNNLNSKLIPPNVKT-HYKV--FEDKRNHEHS-SDDSFELVPPEFHGKEAIRIRNVTKEY
-------------NGK------P-----------------------------EKVEAL--
--Q--GIFLDIYG
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQVTAILGHSRAGKKIILEVLNTLKFPFT--LSVTIYNTQLSEITNV
EEMRR-NTGFCPQF--NIQFDFLTVRE-NLRLFAEIKGIQSEEVE-EEVKRVIMELDIQN
VQDVITKQLSSGQKR-KLTFGIAVLGNPRVRGFLLDEPTARLDPFSRHQVWTFLKEH---
---------------KTNRTILLSTQIVNEAD----------------------------
--------------------I---------------------------MGDKKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CNPERI-TSLIKQL--------------------IPDAKL--T-AESEK-KLVYI--LPL
ER--TNRFLDNLP-----YDH---------GIMNY--GVSMT----TLNEVFMNLEGK-S
LSEETQKQ--------------E-KVNEI--------RDTRTESEMQ----QGPCSLP--
----GLRK-VI-----------------------STGTFWKQQVCAMARL---------R
FL--RRE-KKALLSLLLVLGIPFTPTIFEKIVGVVS-NYTHCWELSSSMYFLSLKQPS--
QAPLTGLLVI-----NNTEGSS-FISDFICCQSNATILYLKIYFL----NWNC-I-KGSY
N-SFCRIRSKS-LDYR---FSVACNTKRMTCFP-VL-MGIISNALLGIFN----------
----------FTEL--IKTECAL-------------NFQNVLMMGTGSSNGPFFLLVLAN
CISPYVGMSSIRDCEQ-KTQSQLWISG-LCPSAYWIGQ-ALVDIPLY-------------
---RLVLFSIYL---INYFMILE-L------SFSLGLMFALVVCIAGCSASLIFFTYVIS
FIFRNRRKNSGFWSLGFLIV-----STCLWNM----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSTSYP00000000828 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVCQQTQALLCKNFLKMWR-----MKG
ESAL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLP-ILLGLGLV--LFS---SFLGSVNFPEMPPQ--DLGRVDT--FNSSSKI-V
VYTPISN------ISQKIMNKTALSPLW------------------------------KG
GT--VIGAPNKKNMNEILLEH-----FPFAVGIVFNDAF-SY----KLKFPDGYDIPFL-
---KE-----EDFSV----------------HCWDV---YY-EFPC-------ELTKY--
WKRGFVTLQTALNAAIIEMTTNRSVVKELMSVTAINMKTLPF---------ISKHTLQ--
NELFLLYCLLYFFPPMYFLSLNV-----------TKERKKKKDLMKMMGLQDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLLY-IGFIFVFSILITI----------IITSTQIIEMTGFMVIFLLFFLYG
LSLIPLAFLTSV----------------------------LLKKAVLT---SLVV-----
FF-LILFWGC--------LGFTAFSKQIPSSLEWILSICSPFAFTTGMVQVIKLDYN---
------LNGVIFPDPSGDSYVMIATFFMLTFDGLIYLILAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1686)
YFDKIFPYT---NEHHYSP
LFFLNSSTCFQHQ-RTDNKV--IEREIDSECP-SGDYFEPVTPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
--R--
PF00005 // ENSGT00760000118965_1_Domain_3 (1686, 1839)
GLLLDVYEGQITAILGHSGAGKSSLLNILSGLAIPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQS--NVQFDTLTVKE-NLRLFATIKGIRLQEVE-REVQQILLELDLQT
IQNNLAEHISEGQKR-KLTFGIAVLGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2301)
TTGLDPFSRHRVWSFLKER---
---------------RADRVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKLIMSNGR
LKCAGS--SVFLK---RKWGL---GYHL--SLYRN-E----------------------I
CDPEQI-TSVINHH--------------------IPDAKL----KTENQEKLVYT--LPL
EK--TNTFPDLFNDLEKCSDQ---------GVTGY--DISMS----TLNEVFLKLEGK-S
TIEQG----------------FQ-QVEIL--------RDSESLNEME----PAHSLFP--
----EMQTA-A-----------------------SDMSVWKMQVCAIARL---------R
FLQFIRG-RKVLWNLLLVFG
PF12698 // ENSGT00760000118965_1_Domain_4 (2301, 2704)
IAVLPLVVESIIYAMSAL-KIDWEFKTELYFLSPGQPP--
QGPRTSLLVI-----NN--TES-NIEDFIQSLKHQNILLEIDDFE----NRNG-TDSLSY
N-GAIIVSGKQ-KDYR---FSLVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQY--IQIKRSPFVFSYE-------------IFFTRLPEAFSFLVWVLS
CTSPYIAMSSVSDYKRKT-KSQLWISG-LYTSAYWCGQ-ALVDISVF-------------
---ILILLLMYL---IFYLQNM---AYL---YVTTKIFFAMVLFTPGYAASLIFLTYIIA
FISRKKRKNSGLWSFCFYFA-----SMITWDML-II--KGFNL-KILITSIALVPSF---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LF--------GFINIFDQSE----------LEFYRHPED---PHADPNAVVFLACLI
PYFQALLFAFVLRCME-LKCGKKAMRKDPVF-RISHQIKDAQPNPEEPVD----EDEDVQ
AERIRTATALT-TSDLD--EKPVIIASCLHKEYTGQRKSCFSKRK--KKVAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEILGLLGPNGAGKSSSIRIISGITKSTAGKVE-LK--GCSSI-SG------------H
LGYCPQENVLWPVLTMREHLEVYAAVKGLKKESAK-----AAITR----LVDAFNLHEQL
NVPAQKLTAGAA---RKLCFVLSILGNSPFLLLDEPSTG----VDPPG-QQQMWQTLQAA
MKTTAAGVLLATHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQLTSV
HTEIVKIFPQAA--QQERSSSL--LTYKLPLADVYPLSQAFHKLETVKHNFSLE---EYS
L-SQCTLEKV----------------------------------------------LLEF
SKEQEVENLD-EEVDT-TMRWKLLPHLDEP---------------------
ENSPPYP00000009632 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRKISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASTPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVTFTNTY-SY----HLKFLLGHGMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSITGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSSFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAF----------VIKSTQFIILSGFMVVFSLFLLYG
LSLVALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGC--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALAIYFEKILPNE---YGHQRPP
LFFLKSSFWSQTQKT-DHVA--LEGEMDADPS-SHDSFEPVPPEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-----------------------------------------K--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPREVD-KE------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------LQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQIRAIARV---------R
LLKLKHE-RKALLALLLILMAGFCPLIVEYTMVKIYQN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGNV-KNYS---FSLACNAKRLNCFP-VL-MDVVSNGLLGMVK----------
----------PSVH--IRTERSTFLENGQ-----DNPI---GFL-----AYVMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNFEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NIFES-DIPFIFTFLIPPA---
--TMI--------GCLFLSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFTLRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--ERPVIIASCLRKEYAGKRKGCFSKRK--NKIATRNVSFCVR
KGEVLGLLGHNGAGKSTSIKMITGDTKPTAGQ----------------------------
------------------------------------------------
PF00005 // ENSGT00760000118965_1_Domain_5 (2989, 3037)
-LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQQLGDFE-EDFDP-SVKWKLLPQEEP----------------------
ENSODEP00000014210 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MSS-L
PF12698 // ENSGT00760000118965_1_Domain_0 (552, 1542)
LLLLLLYILIRL---NGHQLKDFSSLSAM--NLGRVDS--FSH--KFSI
VYTPITR------ETQQIMNTVANASFM----------------------------A--D
KE--VVGLPENEDIEDFTRNY-----PGEIAAVIFTDTY-SY----HLKFFSEGRIPVQ-
---KE----NSDHTG----------------HCYET---Y-ENIYC-------HASLF--
WKGGFVALQAAINAAIIETTTNHSVMEELMSMTGKFMKIYPF---------VSQGGFH--
TDFFLFFCIISFSPFTYYASINV-----------TRERKRMKGLMMAMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFTLVLAFLLAL----------VIKSIQFFFLANFMVVFALFLLYG
LSMTALAFLMSV----------------------------LIKKPFLT---GLAL-----
FF-LTVFCGS--------LGFTALYRHLPASLEWVLSLLSPFAFTLGMVQLLRWDYD---
------LNSNAFPGSSDDSNLIIATLFMLAFDTVAYLVLMI
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFEKVLPNE---YGYQYSP
LFFLKSSFWSQQQT--HHGA--LENVTGPSLL-PNDSFEPMSSEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------SKIEAI--
--K-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-DLTFDIYEGQITAILGHSGAGKSTLLNILSGLSLPTE--GSVIIYNNRLSGGADL
ESVTR-ITGVCPQS--NVQFDFLTVRE-NLRLFARIKGIQPQEVD-KEVQRALQELEMKN
IQGVLAGNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2503)
AGLDPFSRHRVWNFLKEH---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGR
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CSQENI-TSLIKQH--------------------IPAAKL----SAESEGKLVYI--LPL
ET--THKFPDLYKDLDNCPSL---------GIENY--GVSMT----TLNEVFLKLEGK-S
ATEKS---------ESDIR-GGT-QEERA--------GETERLIEME----QILSSLT--
----ERRKP-V-----------------------SGMALWGQQVCAIAKV---------R
FLKLKHE-RKALLSLLLILLFGFSLVLLDYVFVKIHQH-SYTWELSPRSYFLAPGQQP--
HAPLTPLLII-----NH--TGA-SIDKFVRSVERQNIAVEVDVSG----SSDG-EDNPAY
N-GAVVVSTKE-KNYK---FSLACNTKRLNCFP-VL-ADVVSNGRLGMFA----------
----------PSAR--IRTDRSTFVEDID-----VNPL---L
PF12698 // ENSGT00760000118965_1_Domain_4 (2503, 2771)
FV-----GHTIFWLISAS
SCPPYIAMSSIGDYKSKA-RSQLRISG-LFPSAYWLGQ-ALVDVPLY-------------
---MSIFLFMYF---MDYVLNFHEA-----MFTVILHA-LQIPCAVGYTMSLTFLMYVIS
FIFRKGRKNSGIWSFCFYVV-----TTFSVILFYLL--DFFGQ-TTPYGIIFLVPQA---
--TLV--------VALLSI--------------ST------PSFWAEGSHYSLLLHNYLL
PYLHCIIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2882)
LLRCLE-WKFGKKPMRKDPLF-RISPRKNAMCQNPEEPEG----EDEDVQ
IERMKTADALN-STNFE--EKPIIVASCLRKEYMGKRKNCFSKRK--KKIATRNVSFC--
-
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3037)
-EILGLLGCNGAGKSTSIKMISGDIKSTAGQVL-LR--GSSE-------AD----PLGF
LGYCPQENVLWPNLTVREHLEVFAAVKGLSKADAP-----EAIAR----LVEALRLQAQL
QAPVKTLSEGIK---RKLCFALSILGNPSVLLLDEPSTG----MDPEG-QQQIWQAIRAT
IRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPTHVEPL
HTEILRLFPQAA--RQERYSSL--MVYKLPVENVRPLSQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFE-EELDP-SVKWKLLPPEE-----------------------
ENSNGAP00000008691 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MKKISVYQQTQALLHKNFLKKWR-----VKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWGIP-ILIGLYMG--LFS---YFKENFQLPEIPPQ--DLGRIDK--FNDSSMM-V
VYTPVSN------ITQQIMNR-TFASFM------------------------------KG
TR--AIGVPSRKDLNEMLLKN-----IPHPVGIIFNNTF-SY----QLKLLPAYRIPLF-
---KE-----EDFLG----------------NCWGD---YD-EAWC-------TVSIY--
WEEGFVALQTAINAAIIEITTNHSVMEELMSVTAINMKTLPS---------IFKDILQ--
NEIFILFCLLYFSSFIYFVSLNV-----------TKERKKSKALMNMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFIAI----------IITSAQIIVMTGFFVIFTLFFLYG
LSLIALAFLMNV----------------------------LSQKAVLS---NLLV-----
FL-FTLFWGC--------LGITVLYRQLPSSLEWILSICSPFAFTAGMTKIISLDYN---
------LNGVVFPDPSGDSYIMIATFSMLAFDGFIYLILAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NEHHSSP
LFFLSSSFWFPHQRTNSNKV--IEKGIDLELP-SDEDFEPIAPELQGKEAIRVRNVKKEY
-------------KGE------S-----------------------------GRVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFFDIYESQITAILGHSGAGKSSLLNTLSGLSVPTA--GLVTIYNKNLSEIQDL
KEIRK-ITGVCPQH--NIQFDTLTVKE-NLVLFAKIKGIHPQEVE-QEVQQILLELDMHN
IQDKLAGHLSEGQKR-KLTFGIAILGDPQI--LLLDEPTVGLDPFSRQRVWSFLKER---
---------------RANRVILLSTQFLDEAD----------------------------
--------------------I---------------------------LADRKMIMSNGS
LKCAGS--SAFLK---RKWGL---GYHL--SLYRN-E----------------------T
CDLEQI-TSSINHH--------------------IPDATL----KTKTEEKLVYT--LPL
ER--RNQFPDLFSDLDKYSGQ---------GIMSY--DISMS----TLNEVFLNLEGE-P
ANKQD----------------FE-QTGMI--------GDSESLSEME----PTHSPLS--
----ESQKP-V-----------------------SDMGLWRMQVWAMARL---------R
FLKLKRG-RKTLLTLLLILGIALFPLIMEEISFTMIDE-NMDEELKTELYFLSPGQLP--
QGSRTSLLII-----NN--TES-NIEDFIQSLKHQNIALEVDDFV----NRNG-TEGLSY
N-GAIIVSGKD-KDYR---FSVVCNTKRLHCYP-IL-MNIISNGLLHMFN----------
----------QTQD--IRIERSIIF-FVRF------------LIWLGLPDGSLFLSFIAW
CISPYIAMSSASDYKYNV-DSQLWISG-LYPSAYWCGQ-AIVDISIF-------------
---TVIVLLMKL---VLYIRKL---MDI---YIASHIILVMVVISLGFAVSLTFLTYVIS
FVFCKRRKNSGLWSFCFYIV-----LIIMLEIM-FS--DYFSL-TLLIASMVLVPVF---
--SVA--------AFQIFLDKRA----------RQPYEEFTE---LKYDISGADLLICLI
PYFQALFFIFVLRCME-LKCGKNVMRKDPVF-RLSPQSLDNQPNLEEPVD----EDEDVQ
AERIRTSASLS-TSNLA--EEPAIIASCLHKEYTGQKKSCFSKR---KKIAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEILGLLGPNGAGKSSSVRMIAGITKPTAGKVD-LR--GFGSV-GGHRGNS-----TVK
LGYCPQENALWPILTVKEHLEVYAAVKGLRKEDAA-----TAISR----LVNAFELHEHL
NVPVRKLATGAP---RKLCFALSMLGNSPVLLLDEPSTG----IDPTG-RQQMWKAVRAA
VKHSEKGVLLTTHDLAEAEALCDRLAIVVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKGYILEVNVKEPSQVPLV
HSEILKLFPQAA--RQERYFSL--LTYKLPIADVYPLSQAFHKLEAVKRIFSLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELDN-D-EEVDT-TMRWKLLPHSDEP---------------------
ENSCHOP00000009419 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRRRNISVGRQTWALLCKNFLKKWR-----MKR
EILLEWIFS-FLL-LFAY-LSSS---NLHQVNDFSHMPAM--DLGRVDN--FNDS-DYVI
AFAPESK------TTQEIMNKVASAPFM------------------------------KG
RT--IMGLPNEESMDELDLNY-----STDAVRVIFNDTF-SY----HLKFSWGLRIPKM-
---KD----HRDHSA----------------HCHPM---D-KKITC-------EVSKF--
WEKGFVAFQAAINAAIIEITTNHSVMEQLMSVTGINMQILPF---------VAQRGVT--
TDFFIFFCIISFSAFIYYLSINV-----------TQERQHIKAWMRMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFIMATLMTI----------IVKSTQLVIFTGFLVIFTLFFFYG
LSLXXXXXXXXX----------------------------XXXXXXXX---XXXX-----
XX-XXXXXXX--------XXXXXXXXXXXXXLEWTLCLLSPFAFTAGVA-LIHLDYD---
------MNSNVPVDSSKNPYLIIATLFMLVFDALLYLVLTLYFDRILPTE---YGHQRSP
WFFLKSSFWFQHQ---DHVA--LENEIDSEPS-LNDSFEPMSPEFHGKEAIRIKNLKKEY
------------K-GK------H-----------------------------EKVEAL--
--K--GLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTIYNHTLSEMAGQ
DNISR-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIRGIMPQEVE-QEVQRVLLDLEMEN
IHDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHKVWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLLLK---KKWGI---GYHL--XXXXX-X----------------------X
XXXXXX-XXXXXXX--------------------XXXXXL----TVQSEGNLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----SLNEVFLKLEGK-S
ALDES---------DIGIW-GQL-QNDGA--------KDMGHLVELE----QVLSSLD--
----ETRTA-V-----------------------SNMALWRLQLGAIAKV---------R
YLKLKKE-RKSLMAVLLLFGISFLPHLLEHLFFELYSR-SYSWGLSPNMYFLSLGQQP--
QDPLTPLLII-----NK--TGS-SVDNFIHSLKRQNITLEVDAFG----TRNG-TDDPSY
N-GAIIVSGDE-KDYR---FSIACNTKRLNCFP-VL-MDIISNGLLGVFN----------
----------SSGH--IQTERSTYFEEHVS-------Y-EYGYL-----SNAFFWIPVAA
CFTPYIAMSSIGDYKKKI-HSQLQISG-LYPSAYWFGQ-ALVDGPLY-------------
---FSILLVMQI---MDYIFSPDEI-----VFIIQNLL-VQILCSIGYVLSLVFLTYVIS
FIFRNGRKNSGIWSFFFLII-----TVFSIVAIDL---NQYGF-LALFFCTLLIPPF---
--TLI--------GSLFIYSEIS----------PDS------MDYLGTAEPEIVYLVLLI
PYLQFLIFLFVLRCLE-MNFRMKSMRKDPVF-RISPRSSNIFPNPEQPEG----EDEDVQ
MERVRTANAVT-TPDFD--EKPVIVASCLRKEYAGKKKNCFSKRR--KKIATRNVTFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVIGLLGHNGAGKSTIIKMITGDTKPTAGQVL-LK--GSSG-------RD----TLGF
LGYCPQEDALWPGLTVREHLEVFAAVKGLRRGAAE-----AAIAR----XXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-XXXXXRAIRAA
VGSTERGVLLTTHYMVEAEAVFDRVAIVVSGRLXXXXXXXXX------------------
---------------------------XXXXXXXXXXX----------XXXXXXXXXXXX
XXXXXXXXXXXX--XXXRYSSL--MVYKLPVEDMRPLSQAFFKLERVKQSFNLE---EYS
L-SQTTLEQV----------------------------------------------FLEL
SKEQELEGFE-EELSP-SVKWRLLPQEEN----------------------
ENSSHAP00000003072 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MKYGKQCVRKDPLF-RISPTNSDGGTNPEELEN----EDEDVQ
AERARVARVLT-SSNLD--EKPIIIASCLRKEYEGKKKSCFSKGK--KKVATRNISFCVK
KGEILGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STCIRMITGDTRPTAGKVI-LK--KNTTQ----QKDE----MVTI
LGYCAQENIVWKNLTVKEHLEVYAAVKGLKKEDAM-----VTISR----LKDAFKLQKYM
KVPVKELPTGIT---RKLCFALSILENPAVILLDEPSTG----MDPEG-QQQIWKAIREI
FK-KESGAILTTHYMAEAEAVCDRVAIMVSGQL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYILEIKVKEPGQMRHL
HEEILKLFPTAA--KQERYSSL--MVYKLPVEDVHPLSQAFSKLEAAKHAFNLE---EYN
L-SQSTLEQ---------------------------------------------------
---------------------------------------------------
ENSMLUP00000007589 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRERSVCQQTGALLCKNLLKKWR-----MKR
ESLMEWLSS-LLLLLSLY--LYP---TTHEVTDFSSLPTM--DLGRVDS--FKLSTTFTI
VYTPLTN------ITQQIMKKVALASLI----------------------------MA-E
TD--ILGLSDGESFEEVMARL-----PMGAVGVIFTNTF-SY----NLKFSWEKSISNR-
---KE----HRDHTA----------------HCYES---YWEDIDC-------GVASS--
WKKGFVALQAVINAAIIEITTNHSVMEELISVTGKNMKIHPF---------VSQEGTT--
MDLYLFFFLISFSPFIYYVSINV-----------TKERKRMKGLMTMMGLRHSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIATLLLVL----------IIKSIQFVIWTGFMVVFTLFFLYG
LSLIALAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTVLYRHLPASLEWILGFLSPFAFMLGMTQLLRVDND---
------VNSNAFPAFSNYSSQIIAAHFMLAFDIFLYLALTIYFEKILPNE---YGHQYSP
LFFLKSSFWSRQRNA-DHVA--LEDEIYSDPS-SNDSFEPVSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
--K--DLAFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTAYSNKLSEMADL
ENISK-LTGVCPQY--NVQFDYLTVRE-NLRLFAKIKGIPPQEVE-QEIQRVVLELQMDS
IEDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KMDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CVQEKI-TSIVTKH--------------------IPDAQL----SAKSEGKLVYT--LPL
ER--TNKFPELYENLDLCPDL---------GIENY--GVSMT----TLNEVFLKLEGK-A
TIDEP---------GIATS-GGG-QAEGA--------GDTERLVEME----QVLSSLS--
----EMKET-V-----------------------GGMALWRQQICAIARV---------R
LLKLKQD-RKSLLSLLLILGIGFIPNLLEYIISKIYVG-SYTWEFSPHLYFLAPGQPP--
HDPLTQLLII-----NN--TGA-SIDDFIHSVELQNIALEVDASG----NRTG-VDDPSY
N-GAIIVSGHD-KNYT---FSLACNTKRLNCFP-VL-MDIVSNGLLRMVK----------
----------PSAR--IQTGKSTSLLKVLDNP-----F---GFI-----MPTLLCLFLLS
SCAPYIAMSSIDDYKNKV-WSQLRISG-LFPSAYWFGQ-ALVDVPLY-------------
---WLMFLLMYL---LDIILSSRYS-----IITFLDPA-IHIPCVIGAATSLIFFTYVIS
FIFRKGRKNSGIWSMVYFVI-----TLLCVAII-IV--ESPGY-ILLFFINFFVPHI---
--TIV--------GCIILPFYFF----------MF------FEND------GEPLVIFLI
TSLQLIVLIFILRCLE-WKFGKISMRKDPFF-RISPRSSDVHQNPEEPEG----EDEDVE
MERVRTVNALN-STNFD--ERPAIIASCLRKEYTVRRKHCFSKKK--KKIATRNVSFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSSE-------GD----PLGF
LGYCPQENALWPNLTVRQHLDVFAAVKGLRKADAT-----VTITR----LVEALKLQEEQ
KRPVKALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPSG-QQQMWQAIRAS
FNNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLAHVEPL
HSEILRLFPQAA--RQERYSSL--MVYKLPMEDVRPLAQAFFKLERVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELENFV-DELQP-SMKRKLLPQEEA----------------------
ENSCATP00000009541 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YREVVGVIFRDTF-SY----QLKFNWGYRIPPI-
---KE----HTEYTA----------------HCWAM---HGEI-FC-------YLAKY--
WLNGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFIFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFIAGMAQITHLDNY---
------LSGVIFPDPSGDSYIMIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHDGAGKSTLLNILSGLSVSTE--GSTTIYNTHLSEITAM
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2514)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GVSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVFLE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNIKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSHDDI-------------VLDLGFIDGSI
PF12698 // ENSGT00760000118965_1_Domain_4 (2514, 2770)
FLLLITN
CISPFIGMSSISDYKKKV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWELVFVLVVCIIGCAASLIFLTYVLS
FIFRKWRKKNGFWPFGFFII-----LICVSTIL-VS--TQYET-PNLILYMIFIPSF---
--TLL--------GYIMFLIQFS----------LMYMRNLDSLDSRINEVNKTILLTTLI
PYLQSLIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLT--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMITGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQIWQILQAT
IKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVEAL
HTEILKLFPQAA--RQERYSSF--MAYKLPVEDVHPLSRAFFKLEAVKQAFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSAMEP00000011173 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVCQQTWALLCKNLLKKWR-----MKR
ESFMEWLTP-LLLLLCLY--LYP---TDHKVSDFSSLPAV--DLGPVDS--FKDS-TFSL
IYTPVTN------TTQQIMSKVALASFM----------------------------N--G
TK--VLGLSNEENIKELMLHY-----HEEVIQVIFTNTF-SY----HLKFSLEYRIPIK-
---KE----HRDHEA----------------HCSER---G-GDVYC-------QVSQY--
WERGFMALQAAINAAIIETATNHSVMEELMSVTGKNMKTHPF---------VSQGGIA--
ADFFIFFCIISFSSFTYYASLNI-----------TRERKKMKGLMRMMGLCDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVFIFIMAFFLAL----------IIKSVQFVILTGFMAIFTLFFLYG
LSLIALAFLMSV----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTVLYRQLPTSLEWILSFLSPFAFMLGMAQLLRLDYD---
------LNSNAFPNPSDYTNLIIATNFMLAFDLFFYVALTIYFEKILPNE---YGHGYPL
LFFLKSSFWSQKQKV-DRVV--LEDEIDSDPS-SNDSFEPMPPEFHGKEAIRIRNVTKEY
----------K---GK------P-----------------------------DKIEAL--
--K--DLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEITDL
ENIIK-LTGICPQS--NVQFDFLTVKE-NLRLFAKIKGIQSHELD-KEIQRVLLDLEMKN
IQDVLAQNLSGGQKR-KLSFATAILGDPQV--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSEGK
LRCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
HVQENI-TSLIKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TNRFPALYEDLDRCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DVATL-GEA-QAEST--------EDTERLVETE----QVLSSLN--
----EMTKT-I-----------------------GGLALWRQQVCTIARV---------R
FLKLKHE-KKAFLSLLLILGVGICPLFLKSIIMKIYAK-SYTWDLSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDVFG----TKNG-LDDPSY
N-GAIIVSGNT-KSYR---FSLACNTKRLNCFP-VL-MDIISNALLGMIT----------
----------PSAH--IQTDRSTLLRERE-----NNPF---EFQ-----GYTIFWLLSIS
SCTPYIAMRSIDDYKSKA-QSQLWISG-LFPSAYWFGQ-GLVDVPMY-------------
---IFIILLMYL---MEYGLTIQET-----LLIGGDQI-MQILCAVGYAASLTFLTYVIS
FIFRKGKRNSGIWSLCFYMI-----SIFSVFIL-LF--DQYEH-VTLFCVTFLVPHA---
--TLV--------GCMFLYFHEA----------NPD--AQDCLTRDEEPGGVVPFLVFLI
PFLHFIIFVFILRCLE-WKFGKKSMRKDPFF-RISPRSNDVCQNPEAPEG----EDEDVQ
MERMRTANALN-STNSD--EKPVIIASCLRKEYSGKRKCCFSKRK--KKIAARNVSFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVFGLLGHNGAGKSTSIKVITGDTTPTAGQVL-LK--GSIG-------EG----SLGF
LGYCPQENVLWPSLTMKEHLEVFAAIKGLRKADAA-----VTISR----LADALKLQDQL
KLPVRALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FKDTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKNYLLEMKVKTPEQRESL
HQEILRVFPQAA--RQERYSSV--MVYKLPVEDVWPLAQAFFTLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVKWNLLPQEDP----------------------
ENSMICP00000038172 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNKRHMSVVQQTWALLCKNCLKKWR-----MKR
A
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLLEWLFS-LLLVLFAY-LMSL---NLHQINDSPQMPAM--YLGRVDH--FNDT-NYII
AFAPESN------TTQRIMDIVASAPFM------------------------------KG
RT--IMGWPDEKGMDELDLNS-----SVDVVKVIFTDTF-SY----HLKFYWGYRIPRM-
---KE----HRDHSA----------------HCQVM---N-EKITC-------ESSMF--
WEKGFVAFQAAINAAIIEVTTNHSVMEELMSVTGINMKILPF---------IAQGGIA--
TDFFIFFCIISFSAFIYYASVNV-----------AQERQYIKSLMTMMGLREPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMTTLMAL----------VIKSSQVVVLTGFVVVFTLFLLYG
LSLITLSFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGI--------LGFTVLYAHLPAFFEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLNSLNNPYLIIATLFMLVFDALLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKILPTE---YGHRRSP
LFFLKSSFWYQHQRA-NHVV--LENEIDSDPS-SNDSFEPVSPEFHGKEGIRIKNLKKEY
------------T-GK------R-----------------------------EKIEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTIYNHTLSEMTDL
ETVRK-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QQVQQVLRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2421)
AGLDPLSRHRVWNLLKEG---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPESI-TSLVKQH--------------------IPDARL----TAQTEEKLVYV--LPL
ER--TNKFPDLYRDLDKCSNQ---------GIENY--GVSIT----TLNEVFLKLEGK-S
TLDES---------DTGIW-GQL-QNDGA--------KDTGSPVGLE----QVLSFLN--
----GTGKT-I-----------------------SGMVLWRQQVCAIAKV---------R
FLKLKHE-RKSLLTMLLLFGISLIPNLLEYLFYELYVK-SDSWELSPNMYFLSPGQQP--
QAPLTHLLLI-----NK--TGS-SIDNFVHSLRRQNIVLEVDALG----TRNG-TDEPSY
N-GAIIVSGDE-KEHR---F
PF12698 // ENSGT00760000118965_1_Domain_4 (2421, 2771)
SIACNTKRLNCFP-VL-MDVISNGLLGIFN----------
----------SSEH--IQTDRSTSIADHMD-------YDETGFL-----SSSIFWIPVAA
SLTPYIAMSSIGDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVPLY-------------
---FLILLIMQI---MDYIFNPEEI-----IFIIQNLL-IQTLCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----TIFTIVAVDI---NEYGF-LGLLFSALLLPPY---
--TLI--------GSLFIFSQIS----------PNS------MDYLGESESQIVYLALLI
PYLHFFIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRYLE-MNFRKQSMRKDPVF-RISPRSNDVFPNPEEPEG----EDEDVQ
MERTRTANVVT-VTNME--EKPVIIASCLRKEYAGKKKKCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTMIKMICGDTKPTAGQVL-LK--GSGR-------GD----ALGF
LGYCPQENALWPSLTVREHLQVYAAVKGLRKGDAA-----VAISR----LVDALKLQGQL
KAPVGTLSEGIK---RKLCFALSILGTPSVVLLDEPSTG----MDPEG-QQQLWQAIRAT
FRNRERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLVMKVKTPAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYTLPVDDVRPLSQAFFKLEIVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EEVDP-SIRWKLLPQEEP----------------------
ENSOGAP00000001092 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------KNCLKKWR-----MRG
ATFLEWLFS-FFLVLFAY-LMSS---NLHQVNDSPHMPAE--YLGRVDH--FNDS-DYFI
AFAPKSN------TTQLIMDKVASAPFM------------------------------KG
RT--IMGLPDEKGIDELDLNF-----SVDAVKVIFTDSF-SY----HLKFHWGHRIPNI-
---EE----HRDHSA----------------HCEVT---D-KRITC-------KSSTF--
WENGFVAFQAAINAAIIEITTNHSVMDQLMSVTGINMKIFPF---------IAQGGIA--
TDFFIFFCIISFSAFIYYASVNV-----------TQERRYIKSLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATVMAV----------IVKSAQVVVLTGFAVVFLLFLLYG
LSLITLAILMSV----------------------------LIKKPSLT---GLVV-----
FL-LIVFWGS--------LGFTALYSLLPAFWEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNADAHLNSLHNPHLIIATLFMLVFDTLLYLALTLYFDKILCTE---YGHRHSL
LFFLKSSFWFQHQRP-DHAA--LENEIDSDPS-SDDSFEPVSPEFHGKEGIRIKNLKKEY
------------T-GK------R-----------------------------EKIEAL--
--K--GLVVDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLLVPTS--GSVTIYNHRLSEMTDL
ETVRK-LTGVCPQT--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QQVRQVLRDLEMEN
IQDILSQNLSGGQSR-KLTLGIAILGDPQV--LLLDEPTAGLDPLSRHRVWNLLKEG---
---------------RSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKDSISAKR
QKNKAS--TQFIK---KKWRNRHQGRHS--PLHLK-E----------------------R
AETENT-TYRAKHH--------------------IPDAKL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDKCSNQ---------GIENY--GVSIT----TLNEVFLKLEGK-S
TLDEA---------DLEMW-GQL-QSDGA--------KDTGGLVELE----QVLSSLK--
----ETKEA-I-----------------------SGMALWRQQVCAMAKV---------R
FLKLKNE-RKSLLTLLLLFGISLIPYLLEYIFYELYLK-GDSWELSPNMYFLTPGQPP--
QAPLTHLLVI-----NK--TGS-SIDNFIRSLRQQNIALEMDAFG----TRNG-TDEPTY
N-GAIIVSGDG-KDHR---FSIACNTKRLNCFP-VL-MDVLSNGLLATFN----------
----------SSEH--IRTDWCTYFL--------EEKDAGYAYM-----THAFFWIPMAA
CFSPYIATSSITDHNIKA-HSQLRVSG-LYASAYWCGQ-ALVDVLLY-------------
---FLILLVMHT---IDFISNPEEF-----TFIIQNML-IHVTIFTTFAVEINMYEFLWH
HINTT---VHIDWLFINFF-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSBTAP00000009089 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHMKQKSVYQQTQALLCKNLLKKWR-----MKR
ETLLEWGFP-ILLALYMC--IFS---RLNENVRFPGMPPQ--NLGRVDK--YNRSFTD-V
VYTPVSN------LTQQIMNKTALAPVM------------------------------EG
RR--IIGAPDEKSMDEIMLDT-----FSYSVGVIFNDPF-SY----KLKFYQRYYVPIL-
---KE-----DFFTA----------------YCKRT---HI-HFSC-------ALEKY--
WKGGFVPLQAAINAAIIQVTTNHYVMEELMSVTAVNMKTLPF---------IFKENLQ--
NEMFIFYCLLYFSPLIYFLSLNV-----------ARERKNYKDLMNLMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AAFIFVTSIIITV----------IITSTEIIILTGFTVIFTLFFLYG
LSLIALAFLMTV----------------------------LLKKTILT---SLVV-----
FL-LTLFWGG--------VGFSAFYQQLPSPLKWIFSICSPFAFSAGINQIIHLDYT---
------MNGVIFPDASGDSYIMIATFSILTFDALLYLALALYFDKILPYG---NESHYSP
LFFLNSSPCFQHR-RTGSHV--AWKDVDPEPA-AGDYCEPVAPEFHGREAVRIRNVKKVY
-------------KEK------T-----------------------------GKVEVL--
--K--GLSFDIYEGQITAVLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SALLRILSGSSVPTA--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDTLTVKE-NLRLFAKIKGIQPKDVE-QEVQRVLLELDIQN
IQDNLATLLSEGQKR-KLTIGIALLGDPQV--LLLDEPTAGLDPFSRHRIWNFLRER---
---------------KADRVILLSTNLMDEAD----------------------------
--------------------M---------------------------LADRKVILSKGR
LKCAGS--SVFLK---RRWGL---GYHLSLYR--N-E----------------------T
CDPEKI-TSLINHH--------------------IPDAKL----KTESKEKLVYT--LPA
ER--TNKFPDLFSDLDEDCSL---------GVLSY--EVSTS----TLNEVFTKLEGN-S
MAEQD----------------FE-QVEMS--------RDTGRLHEMD----PPCPPAP--
----ETQKA-M-----------------------SIAGLWRLQFWAMARL---------R
FLQLRRG-KKGLLILLFVFGVAVFPLIVESIFYAMLNE-TADLEFKPELYFLSPGQLP--
QGPRTSLLII-----NN--TES-NIEDFIQSLKHQNILLEVDDFE----NRNG-TEDPSY
N-GAIIVSGKR-KDYG---FSVVCNTKQLHCFP-VL-MSVVSNVLLRMFN----------
----------QTQR--IRTERSSYPLGHM-------------LLRTRLPQGSFFLFFVTC
SLSPYIAMNSVSDYKKRT-KSQLWISG-LFPSAYWCGQ-ALVDVSLY-------------
---SLMLLAMYL---IFYLANR---EHI---YLTSRIVFALVVLTLGYAASLVSLMYVVA
FIFRKRRKNSGLWSFCFYVV-----TVIAFGII-VL--FGSGV-PVLIPCMALAPSA---
--TLI--------GFIAFLQERI----------HRYWIKYQE---ANYDLSAADFLVCLI
PYFQALLFMFVLRCLE-AKCGKKIMQKDPVF-RISPQSRDARSNAEEPIG----EDEDVQ
AERIRTATALN--TSIE--EKPVIIASCLHKEYAGQKKRCFSRRR--KKTAVRNVSFCVK
KGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSVRMISGMMTPTAGEVE-LT--GYGSD-PDQQGDI----SIRF
LGYCPQENVLWPSLTTREHLEVFAAVKGLRRADAH-----MAISR----LVDAFRLHEQL
DVPVQKLSGGAA---RKLCFVLSLLGDPPILLLDEPSTG----LDPAE-QKQLWQTVQRA
VRNTARGALLTTHSMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNS-LGKDYILELKLKEASQGMSV
HTEVLRLFPRAA--PQERYSSS--SAYRLPVQDVQPLSQAFHKLETVKRNFNLE---EYS
L-SQCTW-KV----------------------------------------------FLEL
SKEQELGNVD-EEVNT-TMRWKLLCHSEGP---------------------
ENSNLEP00000025880 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MKYGNEIMNKDPVF-RISPRSRETHPNPEEPKE----EDEDVQ
AERVQAANALT-ASNLE--EEPVITASCLHKEYYETKRSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMITGCTKPTAGV----------------------------
------ENSLWPKLTMKEHLELYAAVKRLGKEGAA-----LSISQ----LVEALKLQEQL
KAPVKTLSEGIEKGMRQLCFVLSILGNPSVVLLDEPFTR----MDPEG-QQQMWHILQAT
IKNKERGTLLTTHYMSDAETVCDRMAMMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FDTYLKNTM--KNYF-TLPI
NSSPVLVINLTL--LPDRYSSL--MAYKLPVEDVHPLSRAFFKLEAVKQTFNLE---EYS
L-SQATLEQK----------------------------------------------QCEA
SPDTNVG--------T-TLLVQLVVSESQLKKSA-----------------
ENSTBEP00000003015 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------IP----CFKFPK----SEMSKRERSVCQQTLALLCKNVLKKWR-----IKR
EFLLEWLIS-LLLLLSLY--LY-P--HSHDVIDFSSLPTG--DLGPVDS--FRAP-RFSI
VYSPLTN------TIQQIMNKVASTSFL------------------------------NX
XX--XXXXXXXXXXXXXX-XX-----XXXXXXXXXXXXX-XX----XXXXX--X-XXXX-
---XX----XXXXXX----------------XXXXPCSGIE-NIYC-ED------SIF--
WDNGFT----------LQAAINAAIIEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
XXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXX------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---XXLSWGLLY-AGFILIMALFLTL----------VIKYGQFFILSGFTVVFTLFLFYG
LSLIALTLLMSV----------------------------LVKKSFLT---GLVV-----
FL-LTLFWGS--------LGFTALYRHLPASLEWILSLFSPFAFMLGISQXXXXXXX---
------XXXXXXXXXXXXSNLIIATHFMLAFDTFLYLVLMIYFEKVLPNE---YGRQYSP
LFFLKSSFWSRQQKA-DRVI--LEDEIDSDPS-SSDSFEPISPEFHGKEAIRIRNVTKEY
-------------KGK------L-----------------------------DKIEAL--
--K--DLAFDIYEGQITAVLGHSGAGKSTLLNILSGMSIPTK--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX------------
-----------------------------X----XXXXXXXXXXXXXXXXXXX-XXX---
---------------XXXXXXXXXXXXXXXXX----------------------------
--------------------X---------------------------XXXRKVFLSKGM
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVQENI-TSLVKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TNKFPDLYKDLDSCPGL---------GIESY--GVSMT----TLSEVFLKLEGK-S
AIDESXXX---------XX-XXX-XXXXX--------XXXXXXXXXX----XXXXXXX--
----XX-XXXX-----------------------XXXXXXXXXXXXXXXX---------X
XXXXXXX-XXXXXXXLLIIAIGFSPLLFEYIIVKIYQS-SYTWELSPHLYFLAPGQEP--
RDPLTQLLII-----NK--TXX-XXXXXXXXXXXXXXXXXXXXXX----XXXX-XXXXXX
X-XXXXXXXXX-XNYSFS-L--ACNFKRLNCFP-VL-MDVVSNGLLGMFNP---------
-----------SAR--IQTDRSTFWQEK-------------ENYPFEFLGHSFIWLVWS-
SCPPY-----IDDYKH-KTWSQLRISG-LFPSAYWFGQ-ALVDIPLY-------------
---FSVFVFMYV---MDYIFNSQKT------ILTF---ISQIPCAVGYCISLTFLTYVIS
FIFRKGRKNSGIWSFCFFMI-----TVLSLLGLVI---EMYGL-ESPFYSTFLIPQG---
--TLI--------GCLLLFFEY------------FMSPMYY-E-----EPTVKPFLLFLI
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XISPRSYDGCQNPEEPE----GEDEDVQ
RERVRTANALN-LTNSN--EKPVIIASCLRKEYAGKQKRCFSKKK--KKIATRNVSFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVQ-LK--GSS-------RGD----TLGF
LGYCPQENALWANLTVREHLEVYAAVKGLRKADAK-----VAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGTPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-YGKDYLLEMKVKTPAQVEPL
HTEILKLFPQAA--RQQXXXXX--XXXXXXXXXXXXXXXXXXXXXXXKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELHDFH-EELDA-SMKWKLLPQEEP----------------------
ENSSBOP00000031388 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCRNFLIKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCVA--LFS---SGMRNVQFPGMAPQ--DLGRVDQ--FNSSTLM-I
VYTPVSN------LTQQIMNKTARTPFL------------------------------KG
SN--IIGAPNKTFMEEILLEN-----LPFAVGIIFNETF-SY----KLRFFQGYSIPLW-
---KE-----DDFSA----------------HCWVG---YS-EHWC-------TLTKY--
WNEGFVALQTAINTAIIEITTNQPVMEELMSVTAITMKTLPF---------ITKDLLR--
NEIFILFSLLCFSPFVYFISLNV-----------TKERKKCKNLMKMMGLQDAA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-AGFIFIFSIFITM----------IITLTQIVIMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLAV-----
FL-LTLCWGC--------MGFTVLYEQLPSSLEWILSICSPFAFTAGMTQVIKLDYN---
------LNDLIFPDSSGDSYTMIATFSILLLDGLIYLLLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSPCFQHQ-RPDNKV--IEKEIELEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKLEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLHFDIYEGQITAILGHDGAGKSSLLNILNGLSVPTE--GSIMVYNKNLSEMQDL
EEIRK-ITGVCPQL--NVQFDTLTVKE-NLSLFAKIKGIHLQEVE-QEVQRILLELDMQN
IQDSLAKNLSEGQKR-KLTFGIAILGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLREH---
---------------RANRVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SLFLK---RRWGL---GYHL--SLYRN-E----------------------I
CNPEQI-TTFITHH--------------------IPDAKL----KTENKKKLVYT--LPL
ER--TNTFPDLFSDLDKCCGQ---------GVTGY--DISMS----TLNEVFMKLEGQ-T
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVCAMAWL---------R
FLKLKRQ-TKVLLTLLLVFGIAT
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIIYAMLNE-KSDREFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDSISY
N-GAIIVSGKQ-KDYR---FSIVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTRH--IRIESSPFPINHV-------------RLGTGLPDGSIFLILVLC
STSPYITMGSISDYKKKA-KSQLWISG-LYTSAYWCGQ-ALVDVNVF-------------
---ILILLSMYL---IVYIENI---QYL---YITSEIVFALAIVTPGYAASLVFLMYVIS
FIFRRRRKNSGLWSFCFFFA-----SVNMFTIT-LI--NYFDL-SVLISTIVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFQTFLEMRD----------QPHQREFPE---AYFELSATDFLVSFI
PYFQALLFIFVLRCME-LKYGTKRMRKDPVF-RISPQIRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSNVD--EKPAIIASCLHKEYAGQKKSCFLKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LDQQGDGGDGKLVKF
LGYCPQENVLWPMLTVREHLELYAAVKGLRKGDAR-----LTIAR----LASAFKLHEQL
NVPVQKLAAGTT---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIKAV
VKNTERSVILTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-LGKNYTLELKVKEPSQVTLV
HTEILKLFPQAA--RQERHSSL--LIYQLPMADVYPLSQTFHKLESVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVENFD-EEVDTTTMRWKLLPHSDEP---------------------
ENSMAUP00000025264 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVNREINMCQQTWALLCKNLIRKKR-----MKR
DTFLELLYT-SIILASLS--VIT---EIHEVYDFSHLPNV-
PF12698 // ENSGT00760000118965_1_Domain_0 (582, 1542)
-DLGRIDS--FNDS-SFTI
AYTPVTQ------TTQKIMNKVSLASHM----------------------------T--G
IT--ILAFPDEKNMTELVSRR-----YSDVVRVIFTNTY-SY----HLKFQKGTRIPLT-
---ME----HEDHTA----------------PCSAY---E-DNIFC-------DISQF--
WKDGFVALQAAINSAIIEITTNHSVMEEMMSITGKYIKIDPF---------IGQGGIT--
TDCFLCFYIICFSPLTYYISAGV-----------TRERKKMKGLMTVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GAIIFVVSLLLTF----------IIKFVQFVILTGFMVIFSLFFFYG
LSLISLSFLMSV----------------------------LLRKSFLT---DFVV-----
FF-LTVFCGS--------LGFTALYRTLPVSLEWVLSLLSPFAFMLGMSQLLHLDYD---
------VNSNA--DPTGNPNVIIATIFILFFDCVFYLVLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSE---YGRQHSP
WFFLKPSFWSQQNQALDN-------EIDYE-F-SDDSFEPVSSEFHGKEAIRIRRLTKEY
-------------TEK------S-----------------------------KLTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLSLDVYKGQITAILGHSGAGKSTLLNILSGLCVPTK--GWVTIYNNKLSEKSDL
ENIIK-LTGICPQC--NVQFDFLTVRE-NLRLFAKIKGIREHEVD-NEVQRVLMELEMKN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHRVWNLLKER---
---------------KADRVVVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CVPERI-TSLIKQH--------------------IPDSKL----SAESEGKLNYI--LPL
ER--TNKFPDLYRELERCPDL---------GIENY--GVSIT----TLNEVFLKLEGK-S
TIDQS---------DL------V-QTEGT--------RGSGRIAEME----QLVSCLN--
----EKTNM-K-----------------------GGLVLWWQQLCAVAKL---------R
FLKLKHE-RKSYFFLVLILGIGLLHILLANIHKILHER-DYCWELSPHMYFLTPGQQP--
HEPLTNLLII-----NK--TGA-QIDDFIHSLEKQNISLEVDAFG----TRNG-TEETHY
N-GAIILSGGE-NNYN---FTLACHTKRLNCFP-VL-VDIVSNGLLGLFT----------
----------TSAH--IRTDRSTFPDD-I---HQ--QY---NHI-----PYFISWILLMT
CVPPYISMTSIDDYKNGV-QLQLWISG-LCPSAYWFGQ-ALVEVPIY-------------
---YILTLSMYV---AFYAAAPQES-----MHSTRDLL-AQILYVGGYSMSIIFMTYVIS
FISRKGRKNSGIWSLCFYIV-----TLFSTILI-LF--DFFLD-ILKFCAIVLIPPA---
--TLV--------GSLILHFQNY----------T-----LYDIG-FEEATWNYVFLFFLT
SFLHFAIFLIILRCLE-SKLGMKIMRMDPVF-RISSRVDRVFNNPEEPES----EDEDVR
LERERTANALT-SVESQ--EKPAIIASCLRKEYRGKKKCFVRKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKMITGEAKPSAGQVL-MK--GNSR-------GD----TLEF
LGYCPQENALWSNLLVREHLEILAAVKGMSKGDAA-----VAIAR----LADALKLQDQM
KAPVKTLSEGVK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPAQVEPI
NAEIMRLFPQAA--RQERFSSL--MVYKLPREDVQPLSQAFFKLETVKQGFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDCFE-EELDP-SVQWKLLPQEEA----------------------
ENSBTAP00000040151 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LQEWAMV-LFLGLALC--LFA---ELFRATHFLEQPPQ--VLGRVDE--FNDSDLVLV
AYTPVTN------VTQSIMDKVAAAAFM------------------------------KG
RT--ILGIPNEDAMDRVRPRN-----DSEMVGIVFNDTF-SY----RLKFSWGHRVPIL-
---RE----HFEYSD----------------HCWAL---RDEA-FC-------LLSIY--
WKNGFVAFQTAINAAIIEVTTNHSVMEELISVVGINMRTPPF---------ISKGESI--
NEWFIFICIVYFSPFVYVASLNI-----------TKERKKFKKLMTAMGLQQSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWALMY-AGFVFVVSIFMTL----------VIKLFQMVILTGFVVLVSLFTLYG
LSLIALAFLLCV----------------------------LIKRPILT---GVVG-----
SL-FTVFWGC--------LGFTALYRQLPSSLGWALCLFSPFAFTAGVAQISHQEYH---
------VSGVVFPDPSGESYTMIVLFFLLAFDTLLYLTLTLYFEHILPDE---SGQRHSP
LFFLKSSFWSQHK-NTHHEV--FGNEMNSELS-CDDSFEPVSPEFHRKEAIRIRNLRKEY
-------------KGK------P-----------------------------EKVEAL--
--QETGICLDVYEGQLTAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLSILGGWSACTE--GSATIYNTQLSEIINM
EEIRN-YTGFCPQF--NIYFDFLTVRE-NLRLFAKIKGIPPKEVE-QEVKSIMMELDMHN
IQDVIAKELSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHLVWNFLKER---
---------------KTNHTILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LRCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------R
CNTERI-TSLITQH--------------------ISDAKL----TAENEEKLVYT--LPL
ER--TDKFPDLCRDLENSSDQ---------GIMNF--GVSMT----TLNEVFLNLKGR-S
AINGP---------DPGVG-GLA-EIDVT--------RDPGAESEAQ----QALGSLP--
----EVKQA-A-----------------------SSAALWRRQVCAVARL---------R
FLKLRNE-RKIFLSLLVVFGIALIPTVCEKIVYSVYFH-DHRWEFSPGMYFRSLEQLP--
QPPLTNLLII-----NN--TGS-SIEDAVQSLKHQNLVLEVDDAR----NRNG-SDDPSY
N-GAIIVSGGH-RDYR---FSVACNTKRMNCFP-VL-IGIVSNALLGIFN----------
----------VTEL--IKTERSTFPPDNP-------------RWGMGLLD--FLLLLVVN
CLSPYIGMSSVSDYKQKA-QSQLRISG-LCPSAYWCGQ-ALVDIPFY-------------
---FGILVSIHL---MYY-IFL----ES---TIVLQFMFALVVCVASCAACLILLTYVIS
FLFPSGRKNNGFWSLSFFLI-----SLFMLILL-GL--THSEN--IIIICIILIPSC---
--TSV--------FFLVQMIEVS----------SFTYNGKLKCS--------PKYLLLLF
PYLQIIVFLFIIRCLE-MKYGKETMRKDPFF-RISPRRGEYRPNPEEPEE----EDEDVQ
TERVKTANALT-ASSLD--EKPVIMASCLHKEYKQEKKRCFSARK--TKTAVRNVSFCIN
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3038)
STCIKMITGDTKPTAGVVV-FR--DSGT-PPTRQAGG----GFRH
LGYCPQEDVLWPDLTVREHLDLYSAVKGLTKEEAA-----LSVSR----LADALKLQDQM
ALPAKALPEGAK---RKLSFALSVLGSPALLLLDEPTTG----MDPEG-QLQMWQAIQAI
VKSSARGALLTTHSMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSVQHLKSK-FGKDYLLEVKVKALTLVEPL
HMEILKLFPQAA--RQERYSFV--MAYKLAIEDVHPLSQTFSKLEAVKQAFDLE---EYS
L-SQATLEQV----------------------------------------------FLEL
SKEQELGNLD-DDVDT-TVRWKLLPQEES----------------------
ENSPCOP00000009200 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSMKQKSVYQQTRALLCKNFLKKWR-----MKR
ESSLEWGLS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1491)
ILLGLCLG--LFS---NFLRSVHFPETPPH--DLGRVDQ--FNRS-FRMV
VYTPISN------VTQQIMNKTAFAPLL------------------------------KG
ER--VIGVPNEKHMDKILAEN-----APHAVGIIFNDAF-SY----KLKFVQGYDIPVL-
---SD-----EDLSA----------------HCWEE---YE-EFHC-------LLTSY--
WDRGFVTLQTAINAAIIEITTNHSVMEDLMSVTATNMKTLPF---------ISKDGLQ--
NEMFILYCSLYFSPLIYFVSLNV-----------TKERKKCKDLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFNFIISILITI----------IITSTQIIVMTGFMVIFTLFFLYG
LSLIALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVLYKQLPSSLEWILSICSPFAFTAGMIQ
ENSGT00760000118965_1_Linker_0_2 (1491, 1605)
VK--------
-------------------------------------------------A---YECRYSP
LFFLNSSSCFQHQRA-DNKV--IEKEIDPEHL-SDDNFEPVAPE
PF00005 // ENSGT00760000118965_1_Domain_2 (1605, 1830)
FQGKE-----------
------------------------------------------------------------
-----------------------------------------------------------L
EEIRK-ITGICPQH--NVQFDMLTVKE-NLNLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAEHLSEGQKR-KLTFGIAILGDPQV--RHFSFGIL--------------------------------------------------NF------------------------------------------------G---------------------------SSHRKVIMSNGRLKCAGS--SIFLK---RKWGL---GYHL--SLYRN-E----------------------TCDPEQI-TSFINHH--------------------IPGAKL--K-TENEE-NIVYT--LPLER--TNKFPDLFSALDKYSAQ---------GVMGY--DVSMS----TLNEVFMKLEGK-STIEQGKKT--------------T----------------------YE----Q----------------------------------------------------------------------------------------LCIFPLILETIRMIGTRE-------------KEPG----------------------------------SLYNLGDILLEVDDFK----NRNG-TDGLSYN-GAIIVSGKQ-KDYR---FSLVCNTKRLHCFP-IL-MNIISNGLLRMFN--------------------HTQY--IRIERSPYPL----------------VIWTGLPDGSIFLFLILCSTSPYIAMSSISDYKK-KAKSQLWISG-LYTSAYWCGQ-ALVDINFF----------------IFILLLMYF---IFYIEDVMNV------YTTSKIVLAMVII---------------------------------------------------------------------------------TP------GYAASLV--------------------------------------FLAYV----ISFIFRK-------------------------------------------------RR----------------------------------------------------------------------------------------------KNSGLW-------------S---FCF---------------------------------------------------------------------------YFVTVGKIN---------------NIFK-LHQRKQAIQAAVKNTERGVLLTTHCLAEAEALCDRVAIMVSGRL---------------------------------
PF00005 // ENSGT00760000118965_1_Domain_3 (1605, 1830)
FQGKE----------------------------------------------------------------------------------------------------------------------------------LEEIRK-ITGICPQH--NVQFDMLTVKE-NLNLFAKIKGIHPQEVE-QEVQRILLELDMQNIQDNLAEHLSEGQKR-KLTFGIAILGDPQ
ENSGT00760000118965_1_Linker_3_4 (1830, 2399)
V--RHFSFGIL--------------------
------------------------------NF----------------------------
--------------------G---------------------------SSHRKVIMSNGR
LKCAGS--SIFLK---RKWGL---GYHL--SLYRN-E----------------------T
CDPEQI-TSFINHH--------------------IPGAKL--K-TENEE-NIVYT--LPL
ER--TNKFPDLFSALDKYSAQ---------GVMGY--DVSMS----TLNEVFMKLEGK-S
TIEQGKKT--------------T----------------------YE----Q--------
------------------------------------------------------------
--------------------LCIFPLILETIRMIGTRE-------------KEPG-----
-----------------------------SLYNLGDILLEVDDFK----NRNG-TDGL
PF12698 // ENSGT00760000118965_1_Domain_4 (2399, 3023)
SY
N-GAIIVSGKQ-KDYR---FSLVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQY--IRIERSPYPL----------------VIWTGLPDGSIFLFLILC
STSPYIAMSSISDYKK-KAKSQLWISG-LYTSAYWCGQ-ALVDINFF-------------
---IFILLLMYF---IFYIEDVMNV------YTTSKIVLAMVII----------------
------------------------------------------------------------
-----TP------GYAASLV--------------------------------------FL
AYV----ISFIFRK----------------------------------------------
---RR-------------------------------------------------------
---------------------------------------KNSGLW-------------S-
--FCF-------------------------------------------------------
--------------------YFVTVGKIN---------------NIFK-LHQRKQAIQAA
VKNTERGVLLTTHCLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYTLELKVKETSQVTLV
HTEILKLFPQAL--LIMEKYS-------LPVMDFSSPG-----LENGKGCVC-V---CLH
T-HICTCVLV----------------------------------------------YVSM
L-------FG-KEVDQ-KLNLKFLGGISTSKKQEIKAAIFILAQCKCNRTV
ENSMFAP00000002466 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------ESSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQEKQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHMLSGMADV
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRYSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDEA--------KDIGSLVELE----QVFSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGY--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------ED----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFDP-SVKWKLIPQEEP----------------------
ENSPTRP00000016277 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLM-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTHMDEILLEN-----LPYAMGIIFNETF-SY----KLIFFQGYNNPLW-
---KE------DFSA----------------HCWDG---YG-EFSC-------TLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ITKNLLH--
NEMFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFVTI----------IITFTQIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILNICSPFAFTTGMIQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSMLLLDGLIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-RTNAKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGICPQF--NVQFDILTVKE-NLSLFAKIKGIHLKEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGITILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2303)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTENKEKLVYT--LPL
ER--TNTFPDLFSDLDKCSDQ---------GVTGY--DISMS----TLNEVFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLIFGIA
PF12698 // ENSGT00760000118965_1_Domain_4 (2303, 2704)
IFPLIVENIMYAMLNE-KIDWEFKNELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLLMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFFIYMIS
FIFRKRRKNSGLWSFYFFFA-----STIMFSIT-LI--NHFDL-SMLITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEVRD----------QEHYREFPE---ANFELSATDFLVCFI
PYFQTLLFVFVLRCME-LKCGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCLSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTLREHLEVYAAVKGLRKADAR-----LAIAR----LVSAFKLHEQL
NVPVQKLTAGTT---RKLCFVLSLLGNSSVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGSL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKETAQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPMADVYPLSQTFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEIDT-TMRWKLLPHSDEP---------------------
ENSCSAP00000000683 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTLLEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSV--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMSKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKMLPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFFT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTLYFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-QK------H-----------------------------EKVEAL--
--G--GVVFDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLSVPTS--GSVTVYNHTLSGMADI
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPTAGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVFSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLAILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAVEVDAFG----TRNG-TDDPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHMD-------YE-YGYR-----SNAFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLFILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EDEDIQ
MERMRTANAMA-VGDFD--ETPVIIASCLRKEYAGKKKNCFSKKK--KKIATRNVSFCVK
KGEVIGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTIKMITGDTKPTAGQVI-LK--GSGG-------ED----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFNP-LVKWKLLPQEEP----------------------
ENSEEUP00000002191 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDKMALAPFM------------------------------KG
AE--IIGTLDEETMNVVHPNN-----NSLVVGVVFNNAF-SN----TLKFNWGYRLPII-
---KE----HAEHPA----------------HCWLM---DD-DFSC-------TLTRY--
WQEGFVAFQTAINAAIIEVTTNHSVMEK--------------------------------
----------------------L-----------TSVVGINMR---------TP------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---SFISWTGLL-KELFFTCLLCFSSFVHFASLNVTRERKIKAMTIMGLQE--SAFXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSRLGYY---
------LIGATFPDHSGESHIMIATFFILVFDTVLYLILTLYFERVLPXX---XXXXXXX
XXXXXXXXXXXXXXX-XXXX--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXIRNVKKEY
-------------NGK------P-----------------------------EEVEAL--
--K--GIFLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHRGAGKSTLLNILSGLSVLTK--GSVTIYNTQLSDIPNM
EEKRK-DIGFCPQF--NIQFDFLTVKE-NLRLFAKIKGIHPKEVE-QEVKRIIMELDIQS
IQDVTAQKLNDGQKR-KLTFGIAILGDPQG--LLM-DPTAGLDPFSRHQVWNLLKEC---
---------------KTNHVILLSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---KKWGV---GYHL--XXXXX-X----------------------X
XXXXXX-XXXXXXX--------------------XXXXXX----XXXXXXXXXXX--XXX
XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXX-X
XXXXXXXXXXXX-----XX-XXX-XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXX--
----XX-XXX------------------------XXXXXXXXX--XXXXX---------X
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------XXXX--
XXXXXX----------X--XXX-XXXXXX--------------------------XXXXX
X-XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXX--XXXXXXXXXXXX-------------XXXXXXXXXXXXXXXXXTT
SITPNRGRGGVSDYKE-KTQSQLRISG-LFPSAYWCGQ-ALVDIPLY-------------
---YLILISVYL---FINFMFS-EF------KFPLKFVFALAFCLAGCAVSIIFLTYMIS
FIFRKKR--SGFWSGFLCSI-----SLFVMMILVS---TYFGK-KSLVLCIIFVPIF---
--TPI--------ESLFILLEX------------XXXXXXXXXXXXXXXXXXXXXXXXXX
PYLHCAIFIFVIRYLE-MKYGKETTRKDPIF-RISPKSRKNHPNPQELE----EEDEDVQ
AERMKTANELS-TPSLN--EKPVILASCLHKEYK-EKKSCFSARK--KKIAIRNVSFCVN
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTALKMIAGAIQPTAGMVI-SQ--DCRASPR-HQADD----HLRL
RGYCPQENALWPDFTVKEHLELHAAVRGLGKEDAA-----LSISR----LVDILKLQEQL
TTPMKTLPKGVK---RKLCFALSILGNPSVVLLDEPSMG----MDPKE-QKQIWQTIRTT
VKNKERGILLATNNMAEAEAVCDRVAILVSGKL---------------------------
---------------------------RCIGSIQQMKSK-FGKDYLLEVKMKDPTQVEPL
NTEILKLFPQAA--WQRRYFSM--MVYKVPVEGVHPLSQAFFKLEAVKQTFNLE---EYI
L-SQATLEQV----------------------------------------------FLEF
SKEQELGNFD-E-VDT-TDRSELLPEEEP----------------------
ENSGGOP00000015726 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRCMSVGQQTWALLYKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDTPQMSSM--DLERVDS--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIAFWGI--------LGFPALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSQNPYLIIATLFMLVFDTLLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKPCFWFQHGRA-NHVV--LENETDSDPT-PNDCFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------C-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSRMADK
ENISK-FTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSNRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSIT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVLSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKKE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-TIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSIACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSEH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPMAA
SFTPYIAMSSIGDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----VFIIPNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----VIFSIVATDL---NEYGF-LGLFFGTMLIPPF---
--TLI--------GSLFIFSEIS----------PDS------MDYLGASESEIVYLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-MNCRKKLMRKDPVF-RISPRSNAIFPNPEEPEG----EEEDTQ
MERMRTVNAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GE----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAM-----IAIKR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQMEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDLE-EDFDP-SVKWKLLLQEEP----------------------
ENSHGLP00000002103 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHICVHQQMWTLLCKNCLKKWR-----MKR
ETMLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WLLS-FLLVLFAF-LFSS---NLHQVNDSSQIPAM--DLGRVDS--FNDS-NYII
AFAPESK------TTQEIMSKVASAPFM------------------------------KG
RT--IMGWPDEKSMTELNLNY-----STDAVRVIFNDMF-SY----HLKFSWGHRIPKI-
---KE----HKDHSA----------------HCQAV---D-EKITC-------ESSMF--
WEKGFVAFQAAINAAIIEIAVNHSIMEELMSITGVNMKILPF---------IAQGGIT--
TDFFIFFCIISFSSFIYHLSVNV-----------TQERQYIKSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGFMY-AGFILVMAVLMAL----------IVKSTQIVALTGFMVVFILFFLYG
LSLITLAFLMSM----------------------------LIKKPHLT---GLAV-----
FL-LIIFWGS--------LGFTALYRHLPAFLEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNVHLDASNNSFIIIATLFMLVFDALLYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTQ---YGQRH-S
A---IPPFWCKYQRT-DHAV--LENEIESDPS-SNDSFELVPAEFHGKEAIRIKNLKKEY
------------K-GQ------C-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDIYEGQITVLLGHSGAGKTTLLNLLSGLSLPTS--GSITIYNHTLSEMADF
ETVSK-LIGVCPQS--NVQFGFLTVKE-NLRLFAKVRGILPHEVE-QEVQQILRYLEMEN
IQDILAENLSGGQKR-KLTFGIAILGDPQV--LLLDELTAGLDPLSRHHLWNFLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVLISHGR
LKCAGS--SLFLK---KRWGI---GYHL--SLHLN-E----------------------M
CDPKSV-TSLVKQH--------------------IPDAKL----TEQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCPNK---------GIENY--GVSMT----TLNEVFLKLEGK-S
TIDES---------DIASW-GQS-QSDEI--------KDMASLVVLE----QVLSSLH--
----VKRKI-A-----------------------GGMALWRQQLCAIAKV---------R
FLKLKNE-RKSLLAILLLFGISFFPQLLEHLFYELYQK-SYSWELSPNIYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-SIDNFIQALGRQNIALEVDAFG----IRNG-TEELSY
N-GAITVSRDK-EDHR---FSIACNTKRLNCFP-VL-IDIISNGLLGTFN----------
----------STEH--IQTDRSTFFAEHMS-------Y-DYGYL-----SSAFFWIPLAA
CFTPYIAMSSIDDTKKKV-HSQLWISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYVFSPEEI-----IFIIQNLL-I--------------------
------------------QV-----TIFTIVATDL---SEYGF-LRLFFCTILIPPF---
--TLI--------GSLSMFSEVI----------PEI-----------------SSRIEIL
PYFQFFIFLFVLRCLE-GHIRKKSLQKDPVF-RISPRSSDVFPNPEEPEG----EDEDVN
MERVRTTNAMA-VLDEE--EKPVITASCLRKEYAGKKKNCFSRGK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVVGLLGHNGAGKSTMIKMITGDIKPTAGQVI-LK--RSSE-------GD----TQEF
LGYCPQENVLWPNLTVREHLEVYAAVKGLKKRDAT-----VTITQ----LVEALKLQDQL
KTPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRHAERGALLTTHYMAEAEAVCDRIAIMVSGRLR--------------------------
----------------------------CIGSTQHLKSK-FGKDYLLEMKVRTLTQVEPL
HEEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLSQTFSKLEIVKQSFDLE---EYS
L-SQSTLEQL----------------------------------------------FLEL
SKEQELYDFE-EELDP-SVKWKLLPQEEP----------------------
ENSEEUP00000004065 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----EWLSA-LALLLFLL--LN-P--NGHELVDLSSMPTI--DLGRIDS--FNSS-EFAL
VYTPVTN------TTEQIMKKVSSVSFM------------------------------KD
KE--VFGVSDEEKIQELT-DY-----RLEIIRVIFTNTF-SY----HLKFLLREWIPTH-
---KE----IRDHTX----------------XXXXXXXXXX-XXXXXXXXXXXXXXXX--
XXXXXX----------XXITTNHSVTEQLMSVTGKNMKIHP-------F--VNQEGIS--
TDLHIFFCIISFSSFTYYASISV-----------TRERKRMKGMMTVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFVMALCLAL----------VLKYVDFIILTGFTTVFTLFLLYG
LSLIALSFLMSV----------------------------LVKKVYLT---GLAV-----
FL-LTVFWGS--------LGFLALYRHLPASLEWTLSLFSPFAFTLGMTQLLHMDHD---
------MNSNAYPLPLNNSNIIIATNFMLALDSFLYLALTIYFEKVLPNE---YGHQYSP
LFFLKSSFWSQQKRA-KHVT--LEEDLDLDASSSNDSFEPVSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKTEAL--
--K--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XSVTIYNNKLSEMADR
ENVIQL-TGVCPQL--NVQFDLLTVKE-NLWLFSKIKGIQPHEID-AE------------
-----------------------------F----LPGPTIGPDPFSRILFWSY-KER---
---------------KTGHLIPFSSQIMEVAD----------------------------
--------------------I---------------------------LSDRKVFLSKGK
LRCAGS--SLFLK---KKWGI---GYHL--XXXXX-X----------------------X
XXXXXX-XXXXXXX--------------------XXXXXX----XXXXXXXXXXX--XXX
XX--XXXXXXLYQELDSHPDL---------GIESY--GVSMT----TLNEVFLKLEGK-S
TIDESDTT---------IL-REM-HSEQA--------IDAERLVEME----QVLSSLS--
----DM-K-TI-----------------------FYLSLWRQQLCAIAKV---------R
XXXXXXX-XXXXXXXLLILALGFCPTVVGYIIMKTQQS-SYTWELSPHLYFLAPGQQP--
RDPLTQLLII-----NK--TXX-XXXXXXXXXXXXXXXXXXXXXX----XXXX-XXXXXX
X-XXXXXXXXX-XNYSFS-F--ACNAKRLNCFP-VL-MDIVSNGLLGMAES---------
-----------SAH--IQTDRSTFWEEE-------------ESNIVEFLGYSLFWLILSS
SCAPYLGMSSIDDYKI-KVWSQLRTSG-LFSSAYWFGQ-ALVDIPIY-------------
---FLMFLFMYL---MDSTLNIYDS------LFGFINKVIQIPCVLGYTASLIFLTYVIS
FIFRKGRKNSGIWSFCFYII-----TVVSLCGLIL---DLFGN-TVLYSTTFLVPQI---
--TLI--------GCVILAHHL------------LMFYADE-E-----STGVEPYLVFLI
PLLHFIIFVLILRC-L-EWKGKKSMRKDLVF-RLSPRRSDVQKNPEELE----GEDEDVQ
LERVRSLHALN-STNFE--EKPVVIANCLRKEYTGERKWCCAKSK--KKIATRNVSFCVG
KXXXXXXXXXXXXXXXXXXXXXXXXXXXX
PF00005 // ENSGT00760000118965_1_Domain_5 (2910, 3091)
XXXVL-LQ--GSS-------E-R----EPLF
LGYCPQESALWPNLTVKENLEVFSAVKGLRKEDAA-----VTITR----LVDALKLQDQL
KFPVKTLAEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPXX-XXXXXQAIRAT
FKNTERGAILTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYQLELKVKSLEQAEIL
HTEILKLFPQAA--RQERFSSL--LVYKLPVDDVRPLAQAFFKLETVKQNFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
CKEQERDNFD-EELQP-SVKWKLLPQEEL----------------------
ENSCHIP00000010316 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHMKQKSVYQQTQALLCKNLLKKWR-----MKR
ENLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGFL-ILLALHMC--ILS---HLNQNVHFPGMPPQ--NLGRVDK--YNRSFMD-V
VYTPVSN------LTQQIMNTTAFAPVM------------------------------KG
RR--IIGAPDEKSMDEIMLDT-----FSYSVGVIFNDSF-SY----KLKFYRRYYVPIL-
---KE-----DFFTA----------------YCRRT---NISDFSC-------ALEKY--
WKGGFVPLQAAINAAIIQTTANHYVMEELMSVTAVNMKTPPF---------IFKENLQ--
NEMFIFYCLLYFSPFLYFLSLNV-----------TRERKKYKDLMNLMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AAFIFVASVIITV----------IITSTEIIILTGFTVIFTLFFLYG
LSLIALVFLMTV----------------------------LLKKTFLT---SLLV-----
FL-LTLFWGS--------VGFTAFHQQLPSPLKWVFSICSPFAFSAGLNQIIHLDYT---
------MNGVVFPDASGDSYIMIATFSMLTFDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---HESHYSP
LFFLNSSSCIQHR-RTGSHV--AEKDVDPEPR-SDDHCEPVAPEFQGREAVRIRNVKKVY
-------------KEK------T-----------------------------GKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLCFDVYEGQITAILGHSGAGKSALLRVLSGSSVPTE--GSVTIYNKNLSEMQDL
EEIQK-ITGVCPQF--NVHFDTLTVKE-NLRLFAKIKGIQPKDVE-QEVQRVLLELDIEN
IQDNLATLLSEGQKR-KLTVGIALLGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2297)
AGLDPFSRHRVWSFLRER---
---------------KAGRVILLSTNLTDEAD----------------------------
--------------------I---------------------------LADRKVILSNGR
LKCAGS--SVFLK---RRWGL---PLHVSEGVHRG-E----------------------I
LPPKKGLLHNIWHH--------------------RSDRGP-------CRRGIQ-----MS
LS--PPVALDLFGDLDEGCSL---------GVMSY--EVSTS----TLNEVVTKLEGN-S
VAEQD----------------FE-QEEMS--------RDTGRLHEKD----PPCPSAP--
----ETQKA-V-----------------------SVAGLWRLQFWVMARL---------R
FLQLRRG-KKGLLTLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2297, 2705)
FVFGVAVFPLIVESIFYAVLNE-TTDWEFKPELYFLSPGQLP--
QDPRTSLLII-----NN--TES-NIEDFIQSLKHQNILLEVDDFE----NRNG-TEDPSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-VL-VSVVSNALLRMFN----------
----------QTRR--IRTKRSAYPLGHV-------------LLWTGLPQGSFFLFFVTC
SLSPYIAMSSISDYKKRT-KSQLWVSG-LFPSAYWCGQ-ALVDVSLY-------------
---SLILLSMYL---IFYLANM---VYI---YLTSRVIFALVVMTLGYAASLIFLTYVIA
FIFRKRRKNSGLWSFCFYVV-----TVIAFGII-ML--FAPDV-PVLITCMTLVPSA---
--TL
ENSGT00760000118965_1_Linker_4_5 (2705, 2873)
S--------GFTAFLQQVR----------NVIK----------------CAINFEC
PYFQALLFMFVLRCLE-AKCGKKIMQKDPVF-RISPQSRDARSNTEKPVA----EDEDVQ
AERIRTATALN--TSVE--EKPVIIASCLHKEYAGQKKRCFSRRR--KKTAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEILGLLGPSGAGKSSSVRMISGMMAPTAGEV---------------QGDA----SIRF
LGYCPQENVLWPSLTTRDHLEVFAAVKGLQRADAR-----VAISR----LVDAFKLHEQL
NVPVQKLPGGAA---RKLCFVLSLLGDPPILLLDEPSTG----LDPTE-QKQLWQTIQRA
VRNTARGALLTTHSMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNR-LGKDYILELKLKEASQGMSV
HTEVLRLFPQAA--QQERYSSF--SAYRLPVQDVQPLSQAFHKLETVKRNFNLE---EYS
L-SQCTLEKV----------------------------------------------FIEL
SKEQELGNVD-EGVDT-IMRWKLLCPSEGP---------------------
ENSCPOP00000010788 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRHISVGQQMWTLLLKNCLKKWR-----MKR
ETLLEW
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
FFS-FLLVLFAF-LFSS---NLHQVSDYSQMPAM--DLGRADN--FNDT-NYII
AFAPESK------TTEKIMSKVASAPFM------------------------------KG
RT--IMGWPDEKSMTELDLNY-----SIDAVRVIFNDMF-SY----HLKFSWGRRIPKI-
---KE----HKDHSA----------------HCQAV---D-EKITC-------ESSVF--
WERGFVAFQAAINAAIIELAVNHSVMEALMSVTGVNMKIPPF---------IAQGGIA--
TDFFIFFCIISFSSLIYYLSVSV-----------SKERKYLKSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGFMY-AGFILVMAILMAL----------IVKSTQMVVLTGFTVVFFLFFLYG
LSLITLAFLMSV----------------------------LIKKPYLT---GLAI-----
FL-LIIFWGS--------LGFTALYRHLPATVEWTLCLLSPFAFTTGMAQLIHLDYD---
------VNSNAHLDASNNSYIIIATLFMLVFDTFLYLLLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDRIFPTK---YGRRHSA
MFFLKSSFWCQHRKA-NHVA--LENEIDSDPS-PTDSFEPVSAEFHGKEAIRIKNLKKEY
------------K-GQ------R-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLLLDIYEGQITALLGHSGAGKTTLLNVLSGLSAPTS--GSVTIYGHKLSEMADF
ETLSK-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILSHEVE-QKVQQILRDLEMEN
IQDFLAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2437)
AGLDPLSKHHIWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISHGR
LKCAGS--SLFLK---RRWGI---GYHL--SLHLN-E----------------------M
CDPESV-TSLVKEH--------------------IPDAKL----TEQSEEKLVYV--LPL
ER--TNKFPDLYRDLDRYPNK---------GIESY--GISMT----TLNEVFLKLEGK-S
TMDES---------DIAVW-GQL-QNDGT--------KDTASPVEMETNLDGDLSSLH--
----VTSRI-A-----------------------GGMTLWRHQLCAIAKV---------R
FLKLRNE-RKSLLAMLLLLGVGFVPQLLEYLFYEIYQK-SYSWGLSPDMYFLSPGQAA--
AGPLTHLLVI-----NK--TGA-SIENFLHSLRRQNIALEVDAFG----TRNG-TEELSY
N-GAITVSGDK-QDPR---FSIACNTKRLNCFP-VL
PF12698 // ENSGT00760000118965_1_Domain_4 (2437, 2769)
-IDIISNGLLGIFN----------
----------STEH--IQTGRSTFFEEHAS-------Y-NYGSL-----GSAFFWIPLAG
CFTPYIAMSSIDDTKKKV-HSQLWISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLIQI---MDYVFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLTV-----TIFTIVAADV---SEYTF-LGILFCTILVPPF---
--TLI--------GSLSIFSEIS----------YDS------VDYLGASESQIVFLALLI
PYLQFFIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFVLRCLE-GHFRKKLLRKDPVF-RISPRSSDVFPNPEEPEG----EDEDVR
MERIRTTNAVT-SLDEE--EKPVITASCLRKEYAGKKKNCFSRRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVVGLLGHNGAGKSTVIKMITGDIRPNAGQVI-LK--RNSE-------GD----DLGF
LGYCPQEDVLWPNLTVKQHLEVYMSVKGLKKRDAM-----VTTAQ----LVEALKLQDHL
KTPVKTLSEGIK---RKLCFALSILGSPSVVLLDEPSTG----MDPEG-QQQIWQAIRAT
FRHMDRGALLTTHYMAEAEAVCDRLAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVRSLAQVQPL
HAEILRLFPQAA--RQERYSSL--MVYKLPIEDVQPLSQTFSKLEIGK------------
------------------------------------------------------------
---------------------------------------------------
ENSODEP00000012094 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVARKISVWKQTWALFCKNLLKKRR-----MKR
DTVMEWFYS-AFLLVALY--TFS---TIPDG
PF12698 // ENSGT00760000118965_1_Domain_0 (572, 1542)
DDFSSNHSV--ELGRIDS--FKHP-TFVV
AYAPFNQ------TMRKIMKKASSASSM----------------------------T--G
IK--IIALHDKENMTELISIP-----QEDVVRVVFTNPF-SY----HLKFLQGFRNPTM-
---LK----HRDHSA----------------HCYEF---G-DSLDC-------STMQF--
QTKIFVALQAAINAAIIELTTNHSVMDELMAVTGEHMKLDSF---------LRQEGTI--
MNLFMFTCITCFSPFTYYVSVYV-----------TRERKKMKGWMTIMGLRDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWALLY-AGFVLILAFFLAL----------ITKSVQFVILTGFTVVFSLFFFYG
LSLITLTFLMSV----------------------------LLKKSFLT---GFVV-----
FL-FTVVWGL--------LGLLALYRHLPASLEWTFSLFSPFAFTFGMSQLLHVDFE---
------MSSKE--DSTSDSNLIIATISMLFLDAFCYLALTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGRRHPP
WFFLKSSFWNQQKTP-DRVA--LEDETEAE-F-SNEAFEAVSTEFHGKEAIRIRNLTKEY
-------------RGK------P-----------------------------KGVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTFNIYEGQITTVLGHNGAGKSTLLNILTGMCVPTK--GWVAIYDNKLSEMTDL
ENISK-LTGVCPQV--NVQFDFLTVRE-NLRLFAKIKGIQPHEVD-NEVQRVLQELEMKT
IQDSLAENLSGGQKR-KLTFGIATLGDPRI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2487)
AGLDPFSRHRIWNFLKER---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LAERKVFLSQGR
LKCAGS--SLFLK---KKWGI---GYHL--SLQLD-E----------------------T
CVHKRI-TSLVKQH--------------------IPDAKL----SAERAGKLTYT--LPL
ER--TNKFPDLYRDLESCTDL---------GIEDY--GVSMT----TLNEVFLKLQGK-P
DLDQP---------DIGTL-EDV-QAEGT--------RDTGRLFETE----EAAFSPN--
----GMYKT-K-----------------------TGMALLWQQVCAVARV---------R
FLKIKRE-KKVHFTLVLLLIGGLLHILTAYLRKIVSRD-DHFWGLSPQMYFLTPGQRP--
RDPLSSLLII-----NK--TGA-SIDGFIHSLEKQNIALEVDASG----TRDG-TEELSY
N-GAITVSGDS-TNHR---FSLACNTRRPNCFP-VL-VDVVSNGLLGTLA----------
----------PSAR--ICTHRSSYPR
PF12698 // ENSGT00760000118965_1_Domain_4 (2487, 2695)
EAQ----S-YQF---SNL-----VLLILWITLMP
SLSPSISMTSVDDYKNKA-QFQLWISG-LIPSAYWFGQ-ALVEVGIY-------------
---LSLILLMYV---AFYALKLQGD-----IYTTADIF-IQILYIVGYSLSIIFMTYVIS
FIFRGGRKNSGIWSFCFYFV-----TVVSTVFM-I---DFFKE-TSQFWASIFI
ENSGT00760000118965_1_Linker_4_5 (2695, 2873)
PPA---
--TLV--------GCTLLHFDVR----------TSS---F-----CFKQEKKDDFLVFLV
SYVHFMIFLVTLRCLE-WKLGNKTMRKDPIF-RISTRSSRVFHNPEDPER----EDADVQ
LERVRTANALT-SPNFE--QTPAIIASCLRKEYTEKK-CLFFKKK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEILGLLGHNGAGKSTCIRMITGETKPSAGQVL-LR--GSNE-------AD----PLGF
LGFCPQENVLWPNLTVREHLEVFAAVKGLSKADAP-----EAIAR----LVEALKLQAQL
QATVKTLSEGIK---RKLCFALSILGNPSVALLDEPSTG----MDPEG-QQQIWRAARAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPANVEPL
HTEILRLFPQAA--RQERYSSL--MVYKVPVEDVQPLSQAFFKLETVKQSFEVE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFD-EELDS-TMKWKLLPPEEA----------------------
ENSACAP00000015275 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MELRYLPAGKTQSRHKM----PKEHQKKRSLCQQTGALLWKNILLKWR-----MRI
QSVQELFSS-LSLLLSFL--IMSA--IIVL-HDTVEIPGA--SLGRLDDPVFNIT-GSTI
LYTPDTK------LTRKIMEKLETVSVV------------------------------KG
IK--TKLLKDEKDMIDDY--K------YELIGVEFQDDV-SY----ALRFPMYRAQS-P-
---DE----LSAQIE----------------YCYN----YS-SSHC-------LVPRY--
WFHGFISVQSSIDSALIEEITNHSVWDEMKSISAILMRSPSV---------TPTSSAE--
NSLFFIAVAACFSPFMYFLSQNV-----------SREKRKLKELMKTMGLKDMA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AIYTAIMSSVMAA-----------FLKHWNLSWCSFFALFHLFFLYG
ISSICFCFMISS----------------------------ILKKPKAT---SFVT-----
TI-LIFFFGA--------LGVVTSISRISVTLEWILGIFCPFAFGAGLAKISIYQRY---
------GQPFYMTQLMKEPYV-----YILFFDSVLYMLLTLYFDKVIPDK---YGVPYSP
FFFLKKSYWVKSRKR-LLGDVST---NEQSNI-SNDNFEPVPPEFDGKEEIRLNNIKKTY
-------------EVK------K-----------------------------TKTEAL--
--R--GLSLNIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLHILSGLSKPSN--GSATIFGYDISERADM
EEIRN-ISAVCPQF--NIQFEFLTVKE-NLKTFAKIKGVPSNDIE-KEIQTLMTLLDITG
IQNVQASHLSGGQKR-KLSLAITFLGEPQV--MLLDEPTAGLDPYSRHQVWSILNER---
---------------KADRIILFTTQFMEEAD----------------------------
--------------------I---------------------------LANRKAFISYGK
LTCVGS--SLFLK---KKWGI---GYHL--RMHIN-E----------------------M
CDPERT-TSLVKQH--------------------ISDARL----SEQRENELSYT--LPL
EH--VDRFPGLFCDIDQQTNL---------GIVHY--GVTMT----TMEDVFLKLEGN-E
IIDD-DYG---------VH-RGE-QVEGG------------KLGQME----QEKPLLS--
----DTGKATL-----------------------RGMALWRRQVCGIARM---------H
FLNLKRE-SKVWAALLLLLGIILAPLIIQHIALSIWST-HHKTELHSGLYFEP-GKQF-F
-TGISGLLIL-----ND--TGE-NIDRFIHAVKKQNILLDVVSGS----N---ISDQLVH
N-GAIKVAMKD-QKYR---FTIMCHMEVINCYP-VL-VNIISNAFLQMSN----------
----------SAAR--IRLFSHPLLTIN----------FNEDLWDFFSHGYFISAVFLFP
AFPPNFAMTSVRDYKI-KTWSQLQISG-IFPSAYWYGQ-ALVDIPLL-------------
---CILCVLVFWPCLIQFFIAYE-------GL-RRTIIACSVFFLLGYSTSIITLQYVLA
FVFRKRWYPSSFWSFTLMLV-----TLVITVIH---IAFFRST-YMIYVLMFLIPMY---
--PSI--------TFLQAFIV---------LQRLPLPEDEQWYT----STLKQLWSSTFM
PYLSSATLMLLLCWLV-RKYSKPVMRRDPVF-RISPQSQSIHQNPEEPS----ENDRDVK
EERARAQSALA-SENQE--EKPVVLVHNLRKEYRSKKSCSCLKNKAGGKVATRTVSFCVK
KGEVLGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTISLITGDTNPTAGQVL-IK--GARVS---AVEEN----AGGF
LGYCPQDNALWPNLTVKEHLEIYAAVKGIKKDATA-----SAVDR----IAKALELQEHF
KKTVKSLPAGLA---RKLCFALSILGNPTVVLFDEPTIG----MDPKG-KRQVWRAIRSV
LKDNNQGAILTTHHMEEAEAVCDRVAIMVSGQL---------------------------
---------------------------RCLGSIQYLKSK-FGKNYLLQIKVKGVEEGELL
NTRILQIFPRAA--RQERISTL--LIYKVPMEDALPLSKAFSMLEEAKQSFNLE---EYS
F-SLNTLEQV----------------------------------------------FLEV
CKEQEQVDAD-TVLDT-AFEWKHLQEADL----------------------
ENSSBOP00000037819 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTGALLCKNFLKKWR-----LKR
ESLLEWVNA-LVLLLCLY--TYP---HGHQVNDFSSLLTN--DLGRLDA--FNES-
PF12698 // ENSGT00760000118965_1_Domain_0 (597, 1541)
GFSV
AYTPVTK------ATQQIMNKVASASFL----------------------------A--G
KM--VLGMPDEESIKEFTANN-----SEDIVRVIFTNTY-SY----HLKFLLGHRTPRK-
---KE----HKDHTA----------------HCYET---Y-EDVYC-------AVSEF--
WNEGFVVLQATINAAIIEITANHSVMEELMSVTGKIMKIHSF---------ISQSGII--
TDLFLFACIISFSPFIYYASANV-----------ARERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSIQFIILSGFMVVFSLFLLYG
LSLIPLAFLMSI----------------------------LVKKSFLS---GLVG-----
FL-LTVFCGS--------LGFTSLYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALV
ENSGT00760000118965_1_Linker_0_3 (1541, 1682)
IYFDKILPNE---YGHQRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDSDPS-SNDSFEPVPPEFHGKEAIRIR-----S
VTKE--------YKGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLIFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENLCK-LTGVCPQY--NVQFDFLTVKE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQSLSGGQKR-KLTFGIAILGDPPI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2400)
AGLDPFSRHQVWNHLKER---
---------------KTDHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCVGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------VPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIATL-GEV-QVEKA--------GDTDKLVELE----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQLCAIARV---------R
LLKLKHE-RKALLALLLIIIVGLCPFLVEYIVTKMYRS-TYTLELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSLEHQKIALEVDAFG----TRNG-TDDPS
PF12698 // ENSGT00760000118965_1_Domain_4 (2400, 2769)
Y
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDVVSNGLLGMVK----------
----------PSVH--IHTERGTFLENGQ-----SYPL---EFL-----GYIMFWLLLTS
SCPPYIAMSSIDDCKNRA-RSQLRISG-LFPSAYWFGQ-ALVDVSLY-------------
---FLMFVFIFL---VSYVLEFEEI-----FV-TVIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TLFSVAGF-AF--SMYEI-AIPFIFTFLIPPS---
--TII--------GCLFLSYHFF----------LS------PFFGGE-PKNVQAVLVLLI
PFLHFIIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFTLRCLE-WKFGKKLMRKDPFF-RIYPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYAGKRKGCFSKMK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSAE-------GD----ALGF
LGYCPQENALWPSLTVRQHLEVYAAVKGLRKEDAE-----VAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNMAQVEPL
HAEILKLFPQAA--RQQRYSSL--MVYKLPVEDVRPLAQTFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGNFE-EDFDP-SVKWKLLPQEES----------------------
ENSMLEP00000014051 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNNTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTFFQGYNIPLW-
---KE-----EDFSA----------------HCWDG---YG-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ISKNLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LSGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQS
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2356)
TTGLDPFSRDQVWSLLRQH---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKHKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDK---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FE-EVEMI--------RDSESLNEME----LAHSSFS--
----EMETA-V-----------------------SDMRLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAIFPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----
PF12698 // ENSGT00760000118965_1_Domain_4 (2356, 2704)
NN-------------------------------------------
------------TDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMLN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTT-LI--SNLDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEMRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFVFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERVRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKVAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGKVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTAREHLEVYAAVKGLRKVDAR-----LTIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSGGOP00000013549 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRKISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
VYTPVTN------TTQQIMNKVASTPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVTFTNTY-SY----HLKFLLGHGMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCLISFSSFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTQFIILSSFMVVFSLFLLYG
LSLVALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGC--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LDSNAFPHPSDGSNLIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1694)
YFEKILPNE---YGHRRPP
LFFLKSSFWSQTQKT-DHVA--LEDEMDADPS-SHDSFEPVPPEFQGKEAIRQ-------
------------------------------------------------------------
------AVFPFVL
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1840)
RQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2400)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
FVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICTIARV---------R
LLKLKHE-RKALLALLLILMAGFCPLLVEYTMVKIYQN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPS
PF12698 // ENSGT00760000118965_1_Domain_4 (2400, 2718)
Y
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSVH--IRTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNFEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NIFES-DIPFIFTFLIPPA---
--TMI--------GCLF
ENSGT00760000118965_1_Linker_4_5 (2718, 2873)
LSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFTLRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYAGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSG-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKEDAE-----VAITR----LTDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAX------------XX---------------------------
---------------------------XCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDP-SVKWKLLPQEEP----------------------
ENSSHAP00000002150 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------TSSIYD-YKILSGIGFTASTIFFTYMIS
FIFHKKKKNSSFWSICFFII-----LFQVSIVL-I---NIYKNFSQMILCIIFIPFF---
--TLI--------GIFDLLLEVS----------TTN--NFSNVPDHKDEINKNLFFIILI
PYLHCVIFVFVLRYLEKMKYGKKLVRMDPIF-RIFPSSIDAGPNPEEPEG----EDEDIQ
TERERTANALT-VSNLD--EKPIIIASCLRMEYEGKKKSCFAKKK--KKLATRNISFCVK
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STAIRIITGDISPTAGKVV-LK--RSGTS-MSEEGND----MLQF
LGYCAQENSLWQNITVREHLELYAAVKGMAKEDAF-----IMISR----LADALTLQEYM
KSPVKQLPEGIK---RKLCFALSILGNPAVVLLDEPSTG----MDPEG-QQQIWQAIRAT
LKNKENGAILTTHYMTEAEAVCDRVAIMVSGQL---------------------------
---------------------------RCIGSIQHLKSK-FGKNYLLEIKMKEPEQIRPL
HAEILRLFPRAA--RQERYSSL--MAYKLPIEDVQPLSQAFSKLESVKRTFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKDQELGDFE-EELDT-TVKWKLLPQEEP----------------------
ENSMNEP00000037682 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS
PF12698 // ENSGT00760000118965_1_Domain_0 (550, 1542)
-FLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFGLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2449)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIPIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGM
PF12698 // ENSGT00760000118965_1_Domain_4 (2449, 2718)
VK----------
----------PSVH--IQTERSTFLENGQ-----DNPI---AFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NVFES-DIPFIFTFLIPPA---
--TMI--------GCLF
ENSGT00760000118965_1_Linker_4_5 (2718, 2873)
LSSHLL----------FS------SLSSEE-RMDVQPFLVFLI
PFFHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAK-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSCHIP00000032871 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDKVAAADFM------------------------------KG
RT--ILGIPNEDAMDRVRPRN-----DSEMVGIVFNDTF-SY----RLKFSWGHRVPVV-
---RE----HFEYSD----------------HCWAL---RDEA-FC-------LLSIY--
WQKGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
AFQTAINAAIIEVTANRSAMEELTSVVGINMRTPPF---------ISKGEII--
NEWFIFICIVYFSPFVYVASLNI-----------TKERKKFKKLMTGMGLQQSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWVLMY-AGFISVVSVFMTL----------VIKLFQMIVLTGFMVVVTLFTLYG
LSLIALAFLLCV----------------------------LIKRPILT---GVVA-----
SL-FTVFWGC--------LGFTALYRQLPSSLGWALCLFSPFAFTAGVAQISHQEYH---
------VSAVVFPDPSGESNTMIVVFFLLAFDTLLYLTLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEHILPDE---NGQRRSP
LFFLKPSFWSRHK-STHREV--FGNEMNSELS-CGDSFEPVSPEFHGKEAIRIRNLKKEY
-------------KGK------P-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GICLDVYEGQLTAILGHSGAGKSSLLSILGGWSACTE--GSATIYNTQLSEIMDM
EEIRN-CTGFCPQF--NIYFDFLTVRE-NLRLFAKIKGIPAKEVE-QEVKGIVMELDMHD
IQDVIAKELSGGQKR-KLTFGIAVLGDPQV--LLLDEPTAGLDPFSRHLVWNFLKER---
---------------KTNHTILFTTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LRCAGS--SLFLK---RKWGV---GYHL--SLHRD-E----------------------R
CNTERI-TSLITQH--------------------ISDAKL----TAESEERLVYT--LPL
ER--TDRFPDLCRDLENSSHQ---------GIMNF--GVSMT----TLTEVFLNLKGR-S
AIDEP---------DPRVG-SPA-GIVVT--------PNPGAQSDIP----QALRSLP--
----GVETA-A-----------------------SSAALWRRQVCAVARL---------R
FLKLRNE-RKIFLSLLVVFGIALIPTVCERIVFSVLFR-DHCWEFSPGMYFLSLEQLP--
QAPLTDLLII-----NN--TGE-NIEDVVQSLKRQDLALEVDDAR----NQNG-SDDPSY
N-GAIIVSGGH-KDYR---FSVACNTKRMNCFP-VL-IGIVSNALLGIFN----------
----------VTEL--IKTERSTL-QDDP-------------RWAIGILD--FLLLLVVN
CLSPYVGMSSVSDYKQKA-QSQLWISG-LCPSAYWCGQ-ALVDIPFY-------------
---FGILVSVHL---MYY-IFL----ES---TIVLEFLFALVVCVAGCAACLTLLTYVIS
FLFPTGRKNNGFWALSFFLI-----SLFMLILL-GL--THAEN--IIILCIILIPSC---
--TSV--------FFLARMIEVS----------SFTY---------------CIFHLDHV
PYLQIIVFLFIIRCLE-MKYGKETMRKDPFF-RISPRRREYRPNPEEPEE----EDEDVH
RERVKTANALA-ASGSD--EKPVILASCLRKEYTQKRKRCFSARR--TKTAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCIN
KGEVLGLLGHSGAGKSTSVKMITGDTTPTAGVVR-GV--GGSP-AHTRQAGG----GPGD
LGYCPQEGALWPSLTVREHLDLYAAVRGLAKDEAA-----LSVSR----LADALKLQDQM
ALPTKALPEGAK---RKLSFALSILGSPAVLLLDEPTTG----MDAEG-QLQMWQAIQAI
VKSSARGALLTTHSMAEAEAVCDRVAVMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEVKVKALTVVEPL
HTEILKLFPQAA--RQERYSFV--MAYKLPIEDVHPLSQTFSKLEAGKFRL---------
L-KLNVLEIV----------------------------------------------FLEL
SKEQELGNMD-DDVDT-TVRWKLLPQEES----------------------
ENSCANP00000032186 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKKEISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HRDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFSLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFIALYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRHPP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILCGLSIPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2470)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICTIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYHN-SYTWELSPHLYFLAPGQQP--
HDPLTRLLII-----NK--TGA-SIDDFIHSVDHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
---------
PF12698 // ENSGT00760000118965_1_Domain_4 (2470, 2719)
-PSVH--IQTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NIFES-DIPFIFTFLIPPA---
--TMI--------GCLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
SSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFFIFLFILRCLE-WKFGKKLMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSCAFP00000016145 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTKRQISVCQQTWALFCKNLLKKWR-----MRR
ESF
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
MEWFNP-LLLLLCLY--LFP---TNHKVNDFSSLPDM--DLGPVDS--FKDS-LFSI
VYTPITN------TTQQIMDKVALASFM----------------------------K--D
KK--VLGLSNEESIKEVMTHY-----PEEIIQVIFTNTF-SY----HLKFTLGHRIPTR-
---RE----HRDHEA----------------HCYNL---S-EGVKC-------QVSKY--
WKQGFVALQAAINAAIIETTTNHSVMEELMSVTGKNMKIHPF---------IRQGGIV--
ADFFIFFCIISFSSFTYYASINV-----------TRERKKMKVLMKMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AVFIFIMALFLAL----------IIKSVQFVILTGFMAIFTLFFLYG
LSLIALAFLMSV----------------------------LVKKSFLT---GLIV-----
FL-LTIFWGS--------LGFTALYRHLPTSLEWILSFLSPFAFSLGMAQLLHLDYD---
------LNSNAFPYPSDDSKLIIATNFMLAFDLFFYVALTI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---HGHEYPP
LFFLKPSFWSRQHKA-DHVA--LEDEIDSNPS-SNDSFEPMPPEFHGKEAIRIRNVTKEY
----------K---GK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEITDL
ENISQ-LTGICPQS--NVQFDFLTVKE-NLRLFAKIKGIRPHELD-KEIQRILLELEMKN
IQDVLAQNLSGGQKR-KLSFATAILGDPQV--FLLDEPTAGLDPFSRHQVWNLLRER---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
HVQENI-TSLIKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TNRFPALYEDLDRCPSL---------GIENY--GVSMT----TLNEVFLKLEGK-P
AIDES---------DFAML-GEA-QAERT--------GDTERLVETE----QVLSSLN--
----EMRTT-L-----------------------GGMALWRQQICTIARV---------R
FLKLKHE-RKVFLSLFLILGIGICPLLLENIIMRIYER-SYTWDLSPHLYFLAPGQQP--
RDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDVFG----TKNG-LDDPSY
N-GAITVSGNT-KNYS---FSLACNTKRLNCFP-VL-MDIISNALLGMIT----------
----------PSAH--IQTDRSTFSSERQ-----SNPF---EFP-----GYTTFWLILAS
SCAPYIAMGSIDDYKNKI-QSQLRISG-LFPSAYWFGQ-ALVDVPMY-------------
---CLIFLLMYL---MDYGLNLQET-----FFKITSPI-IQIPCAVGYSTSLIFLTYVIS
FIFRKGKRNSGIWSFGFCMI-----TAFSVFIL-LF--DYHEH-VALYCLIFLVPQT---
--TLI--------GCMVFYFIQA----------MA-------YYTTQEPRSVGPFLVFLI
PFLHFIIFLFTLRCLE-WKYGKKSMRRDPFF-RISPRSNDVCQNPEALEG----EDEDVQ
MERVRTADALN-STNSD--EKPVIIASCLRKEYSGKRKYCSSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIQVITGDTKPTAGQVL-LK--GSSG-------DG----SLGF
LGYCPQENVLWPNLTVKEHLEVFAAVKGLKKADAA-----VTISR----LADALKLQDQL
KLPVKTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FKNTERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKNYYLEMKVKTPEQRESL
HQEILRAFPQAA--QQKRYSPV--MVYKLPMEDVRPLAQAFFTLERVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EEPDL-SVKWKLLPQEDP----------------------
ENSSARP00000011563 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------TSHFKLLS----QKMNKREISVCRQTWALLCKNLLKVWR-----MKR
EHLMEWSNS-LFLLFCMY--IHN---MSHFIEDFSSLPVL--DLGRVDS--FRDS-TFTI
AYTPVTN------TTQQIMGKVASASFM----------------------------K--D
NE--ILGHPDEKSIEEFTEAH-----MEEVIRVIFTNTF-HY----HLKFLLGYRIPTK-
---KE----HSDHTX----------------XXXXX---XXXXXXX-------XXXX---
XXXXXXXXXXXXXXXXXXVTTNHSVMEQLMSITGKTMKLHSF---------ISQDGIM--
TDISIFLCIIYFSPFTYYVSQNV-----------TRERKKMKGFMVMMGLQNSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALLIAL----------LIKSVQFVIMTGFLMVFIHFFLYG
LSLIALCFLVSV----------------------------LVKRSFLT---ALVV-----
FL-LTVFCGT--------LGFTALYRHLPVPLEWILSLLSPFAFTLGMAQILHLDYD---
------LNSNVFPDPPDTSHLIIATDFMLFFDIFLYLVLMIYFEKILPNE---FGHRHPP
LFFLKSSFWSRQQKT-EHVA--LEDEIDSDPF-SNDSFEPMSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAV--
--K--DLVLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSIPTQ--GSVTIYNDKVSETNGL
EAVSK-LIGVCPQS--NVQFDFLTVRE-NLRLFAKIKGIPPCDVE-Q-------------
----------------------------EI--FLLDEPTAGLDPFSRHHVWKFLRER---
---------------KMDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGR
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
SSPAKI-TSLIKQH--------------------IPDAKL----SSKSEGKLVFT--LPL
ER--TNKFPELYKNLDSCPDL---------GIENY--GVSMT----SLTEVFLKLEGK-S
AIDES---------EMSVL-GDV-QSEQA--------INTERLTEMA----QALSSLS--
----KVRRM-R-----------------------SGMALWTQQVCAIARV---------R
FLKIKHE-HKALLSLLLILGVAIVPLLLEYVLMKINQN-SYTWELSPHLYFLAPGQQQ--
RDPLTPLLII-----NK--TXX-XXXXXXXXXXXXXXXXXXXXXX----XXXX-XXXXXX
X-XXXXXXXXX-XNYS---FSLACNTKRLNCFP-VL-MDIVSNGLLQMAK----------
----------SSGH--IQTDRSTFYEXXXXXXXXXXXX---XX----------XXXXXXX
XXXXXXXXXXXXXXXSKI-RSQLRISG-LFPSAYWFGQ-ALVDIPVY-------------
---FSMFLFMYL---MDLGFYYEMTIWICQXXX-----------XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXV-----TLFSAAII-IT--QNSES-ALVYSLIVFIPQV---
--TLI--------GYLFLSDYVF----------IPD--IFD-------VNRVEPSPIFLF
PFLHCIIFVLILQCLE-WKFGKKPMRKDPLF-RISPRSSDWCPNPEEPEG----EDEDVR
TERVRTVNALN-STDLE--EKPVIIASCLRKEYARKRKHCFSKSK--KKLAARNVSFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTSIRVITGDTNPTAGQVI-LK--GSSG-------EA----PLEF
LGYCPQENVLWPNLTVKEHLEVFAAVKGLSKGDAA-----VSIPX----XXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXEAIRAT
IRNTERSALLTTHYMAEAEAVCDRVAIMVSGRI---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVRTPEQGETL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFLKLET--------------
------------------------------------------------------------
---------------------------------------------------
ENSHGLP00100002359 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKRKISVCQQTWALFCKNLIKKKR-----MKR
DTLMEWLYS
PF12698 // ENSGT00760000118965_1_Domain_0 (550, 1542)
-AFLLLILC--TFY---TLHEVYDFSSMPPV--DLGRIDS--FNDS-AFVI
AYTPFNK------TTQRIMNKVSSASFM----------------------------T--G
RK--VIAFPDEENMTELISTH-----YEDVVRVIFTSPF-SY----HLKFLRGSRIPII-
---KE----HQDHSV----------------HCHEV---R-DSFDC-------GISQF--
WTEGFVALQAAINAAIIEISTNHSVMEELMSVTGKHMKIDPF---------IGQEGKI--
TDFFICICIICFSPFTYYVSLSV-----------TRERKKMKCLMTMMGLQDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLLY-AGFVFILTLFLAF----------IIKSVQFVILAGFMVVFSLFFFYG
LSLIALAFLMSI----------------------------LLKKPFLT---GLVV-----
FL-LTVTWGG--------LGFVALYRYLPVSLEWILSFFSPFAFTLGMAQLLHLEFD---
------MNSNA--DSMGDPNLIIATIFMLFLDSLFYLALTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRHSP
LFFLKSSFWCQKKTA-NHVA--LENETESE-F-SDEAFEPVSTEFHGKEAIRIRNLTKEY
-------------RRK------P-----------------------------KNVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLAFDIYEGQITAVLGHSGAGKSTLLNILTGLCVPTK--GWVTIYNNKLSEITDL
ENISE-LTGVCPQS--NVQFDFLTVKE-NLRLFAKIKGIQPNEVD-NEVHRVLQELEMKN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2402)
AGLDPFSRHRVWNFLKER---
---------------KAGHVILFGTQFMDEAD----------------------------
--------------------I---------------------------LADRKLFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CVHERI-TSLVKHH--------------------IPDAKL----SAENEGKLIYI--LPL
ER--TNKFPDLYRDLESCPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
DIDQP---------DLCAL-GDV-EAEGP--------RETGRLFEMG----ETVSSLS--
----GMSET-Q-----------------------AGLALLWQQVCAIARV---------R
FLKIKHE-RKALFILILIFGSGLLHILAANAHKIFYPE-DYCWDLSPHMYFLTPDQQP--
QKLLSNLLII-----NK--TGA-SIDDFIHSLEKQNIALEVDAFG----TRNG-TEELSY
N
PF12698 // ENSGT00760000118965_1_Domain_4 (2402, 2704)
-GAIIVSGNG-KNYS---FSLSCNTKRLNCFP-VL-VDIVSNGLLGMLS----------
----------PSGS--IHTDRSTYPDVDD---IY-SQF---NNL-----AYLISWIVLMS
CLSPYISMTSIDDYKNKA-QLQLWISG-LNPSAYWFGQ-ALVEVPIY-------------
---FSLIFFMYL---VYYTSKVKGD-----IYTAVDVL-IEILYIVGYSVSVIFMTYVIS
FIFRNGRKNSGIWSFCFYFV-----TLVSAAVM-G---DFLGD-IFLYCVSALIPFA---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LV--------GCTMLHFDHR----------I-----YHDA--PSEQGKKYDFLVFLI
PYVHLIIFLVILRCLE-CKFGKKTMRKDPVF-RISPRTSSVFHNLEDPEG----EDEDVQ
LERVRTSNALT-SPNFE--QKPAIIASCLRKEYTEKK-CLFFKRK--KKTAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIRMITGETKPSAGQVL-LR--GSSS-------PE----PQGF
LGYCPQENVLWPSLTVREHLQVFAAVKGLRKGDAE-----VAVTR----LVEAFKLQDQL
QAPVRTLSEGMK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQIWKAIRAT
LRDTERGVLLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPTQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLSRAFFKLETVKQSFDME---EYS
L-SQSTLEQVRQFLSFYFIQGIQLYSVGARE-------GRATS---VSLLFSF-------
----FPFRFS-WSSPR-SKKWTILMRNSIPP--------------------
ENSXETP00000047603 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------HF------------------------------LD
IK--VQEFADEEELIEA-VSN------MSMVAVTFVDEF-SY----HIRYQLPKRKH-P-
---ND----Y--FAY----------------MGNCG---DD-LSYC-------NPTYY--
WSEGFLSLQASIDSAIIDVSRLLRFVFE------------FS---------FFKELW---
FGM-I-WIILCTFVMIIIIAVELSAISYCSLKIGGSIFKNKFXTLRLMRLQDLA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-SCYVFIVANLMTL-----------VTKPFVFITSSYGIIMFMFFLYG
VALMSFTFMLSA----------------------------LFRNPRAT---AIAG-----
FF-ITLLLSA--------LGLILLSKHVPKSVEVLLSIFPQFAFAVGITQSVHMEND---
------QEGVYFSDLTGGSSHMLSCFISLVLDSVFYMGLTLYFEKVLADK---HGVKHEP
LFFLKASYWSKEKPS-PLM---AQTDDSGESS-LGHFVEKVPADLHGKEAIRIHGVKKTY
-------------YDK------D-----------------------------KNTEAL--
--R--GLDLNIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNILSGMCPTSG--GSATVCNYKLSNMRHL
EEIKK-RVGFCPQG--DIKFDPLTVKE-NLTVFAMIKGIPSKEVA-HKVQTVLSDLQMND
IENIEASKLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPCSRHNIWTILKES---
---------------KADRVTLLSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVVISKGK
LKCVGT--SLFLK---RKWGV---GYHL--RMQVS-P----------------------S
CDVELM-TSIIKQH--------------------IPSTKL----TTQNEEELTYT--LPF
EN--MDVFPDLFLHLDGQVGN---------SIVNY--GVSMT----TLDDVFLKLEGE-G
EIESGDYD---------VF-NPE-SRTTE--------DREDFSTEME----ESLLQMS--
----DSGNVTL-----------------------SGWELWRQQVLAVARI---------R
SLKLRHD-TKSFRSILLLLVVITLPPIIIIITSNIVNT-LDAWELTPHLYFQSPRNRL-N
-KYYTDLLIC-----NN--TGS-SIEDFVGAVKEQNIEVQVVNGE----Y---DMETVKY
R-GAIEVSQME-KGYN---FTIVANPKAFNSLP-VL-LNIISNALLKILK----------
----------VSGH--FRVWNHPITTDG----------TDIIFLPYMSLI---FFIIFAS
AFCPHIAMSSTEDNRI-NARNQLRISG-LFPSAYWFGQ-ALVDVILY-------------
---WILLFLMVA---IFFAF--YSY----ILLDFVPAMVMVISSLFNIYYVLFFRQYFV-
----L-----HNFIQFVNSV-----YLTFIFSLQ------TST-FPVMFMDVF----MFR
LFTIY--------YFVFPASAL-SGIMEYTLGSWKSEDPVGRQDDVGNPWS-HCCFILVL
PYLHIIIFFVLLWFLE-WKFGLRSLTIDPLF-RISRRKITTKKNPEELG---NDVDEDVL
AEKERVKKAAT-IANVE--EKPVIIADSLRKEYKVKKGGSFFKKN--KRAATKNVSFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGPNGAGKTTSMYMLAGEVKPTAGEVL-LC--GNDPVG-----------STGF
LGYCPQDNPLWPNLTVKEHLEIYAAVKGMKKEDAS-----IAINR----VASALELKEHM
GKAARKLSLGVS---RKVCFAISMLGNPNIVLLDEPSTG----LDPKG-QQRLWRAIRAA
FKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQQLKSK-FGKGYLLEIKVKESHQVDQI
HNEIIRIFPHAA--RQDRFSSL--LVYKIPMDNVQSLSQAFLLLEEGKHCFSYV---V--
I-IAFVASQV----------------------------------------------FIEL
AKEQEKEDFE-L--NN-TFQWRHLSQEDKLLY-------------------
ENSRROP00000003700 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLVFFQGYNVPLW-
---KE-----EDFSA----------------HCWDG---YG-EFSC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ITKNLLH--
NEIFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGFIY-AGFIFIISIFITT----------IITFTKIIVMTGFMVIFILFYLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPKI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIDQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMRLWRMQIFAMAWL---------R
FLKLKRQ-AKVLLTLLLVFGIAV
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQHILLEVDDFD----NRNG-TDGLSY
N-GAIIVSGKQ-EDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IQIESSPFPLSHM-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLSMYL---ILYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTA-LI--SHFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEVRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFVFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEIFGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTVREHLEVYAAVKGLSKADAR-----LTIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----VDPTG-QQQMWQAIQAV
IKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HNEILKLFSQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSCSAP00000000707 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MEELTSVIGINMKMLPF---------ISKGEIM--
NEWFIFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-ICFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYGQLPLSLGWVLSLLSPFAFIAGMAQITHLDNY---
------LSGVIFPDPSGDSYIMIATFFILAFDALFYLILTLYFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
--Q--GISFDIYEGQITAILGHDGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSVSTE--GSTTIYNTQLSEITAM
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPTAGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCVGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GLSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVAAL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIMLEKIMYKVIHK-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNIKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSHVSR-------------VLIY--IRGNTAEG----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSCJAP00000000306 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCRNFLMKWR-----MKR
ESLLEWGLS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
ILLGLSVA--LFS---SGMRNVQFPGMAPQ--DLGRVDQ--FNSSSLI-I
VYTPVSN------LTQQIMNKTAHTPFL------------------------------KG
SN--IIGAPNKTFMEEILLEN-----LPFAVGIIFNETF-SY----KLRFFQGYSIPLW-
---KE-----EDFSA----------------HCWDG---YG-ERWC-------TLTKY--
WNEGFVALQTAINTAIIEITTNQPVMEELMSVTAITMKTLPF---------ITKDLLH--
NEIFILFSLLCFSPLVYFISLNV-----------TKERKKCKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-AGFIFIISIFITM----------IITLTQIVIMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLCWGC--------MGFTVLYEQLPSSLEWILSICSPFAFTAGMTRVIKLDYN---
------LNDVIFPDSSGDSYTMIATFSILLLDGLIYLLLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFFNSSSCFQHQ-RTDNKV--IEKEIELEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLHFDVYEGQITAILGHDGAGKSSLLNILNGLSVPTE--GSVMIYNKNLSEMQDL
EEIRK-ITGVCPQL--NVQFDTLTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDSLAKHLSGGQKR-KLTFGIAILGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLREH---
---------------KANRVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLYRN-E----------------------I
CNPEQI-TFFITHH--------------------IPDAKL----KTENKTKLVYT--LPL
ER--TNTFPDLFSDLDKCCSQ---------GVTGY--DISMS----TLNEVFMKLEGQ-T
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVCAMAWL---------R
FLKLKRQ-TKVLLTLLLVFGIAT
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2697)
FPLIVENIIYAILNE-KSDREFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGISY
N-GAIIVSGKQ-KDYR---FSIVCNTKRLHCFP-VL-MNIISNGLLHMFN----------
----------HTQH--IRIDSSPFPISHV-------------RLATGLPDGSIFLILVLC
STSPYITMGSISDYKKKA-KSQLWISG-LYTSAYWCGQ-ALVDVNVF-------------
---ILILLSMYL---IVYIENM---QYL---YITSEIVLALAIVTPGYAASLVFLMYVIS
FIFRRRRKNSGLWSFCFFFA-----SLNMFTIT-LI--NYSDL-NVLISTIVLVPS
ENSGT00760000118965_1_Linker_4_5 (2697, 2873)
Y---
--TLL--------GFQTFLEMRE----------QPHQREFPE---AHFELSVTDFLVSCI
PYFQALLFIFVLRCME-LKYGKKRMRKDPVF-RISPQIRDAKPNPEEPTD----EDEDVQ
AERIRTATALT-TSNVD--EKPVITASCLHKEYAGQKKSCFLKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LDRKGDGGDGKFLKF
LGYCPQENVLWPMLTVREHLEVYAAVKGLRKGAAR-----LAIAR----LASAFKLHEQL
NVPVQKLAAGTT---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIKAV
VKNTERSVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGTIQHLKSK-LGKNYTLELKVKEPSQVTLV
HTEILKLFPQAG--RQERHSSL--LIYKLPMADVYPLSQTFHKLESVKHNFNFE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVENFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSSSCP00000025011 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKREMSVCQQTGALLCKNFLKKWR-----MKR
EPI
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
MEWLIA-LFLLLALY--LYP---HVHEVNDFSSLPPM--DLGQVDS--FNAS-QSEI
AYTPVTN------TTLQIMNIVASASFM----------------------------K--D
TE--VLGLSNEESIKKLTADH-----PEEIIGVIFTDTF-AY----HLKFSPGHRIPVR-
---KE----HMDHTA----------------HCYEM---N-EAVDC-------EVSEF--
WKKGFVAVQAAINAAIIEFTTNQSVMEQLMSVTGKNMKIHPF---------ISQGGIA--
TDVFIFFCVISFAPFTYYASINV-----------TRERKKMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLTL----------IVKSAQFIILSGFVVIFALFLLYG
LSLIALTFLMSV----------------------------LVKKSFLT---GLTV-----
FL-LTVFCGS--------LGFMALYRYLPASLEWILSFLSPFAFMLGMTQLLRSDYD---
------LNSNALLDASDSSNLIIATNFVLTFDIFFYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDRILSSE---YGHRYSP
LFFLKSSFRSKQQRT-DHIA--LEDELDSNPS-SNDSFEPMSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLAFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYDNKLSQTAYL
ENISK-LTGVCPQI--NVQFDFLTVRE-NLRLFAKIKGIQPHEID-KEVQRVLLELEMKN
IQDILAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2367)
AGLDPFSRHQVWNILKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGR
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CVQEKI-TSLVKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--THKFPELYEDLDRCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
SLDES---------DSANL-GEV-PAERS--------GDTERLVEME----QYLSLLN--
----EPRQT-I-----------------------SGLALWGQQIRAIGRV---------R
LLKLKHE-RKALLSLLLILVVGFCPLLLEYIIMKIHQN-SYTWELSPDLYFLAPGQQP--
RDPLTQLLII-----NK--TGA-SID
PF12698 // ENSGT00760000118965_1_Domain_4 (2367, 2719)
DFIHAVENQNIALEVDVLG----TRNG-LDDPSY
N-GAIIVSGSE-KNYS---FSLACNTKRLTCFP-VL-MDIVSNGLLGLAE----------
----------PSAH--IQTERSTFLEKDQ-----DNSF---ESL-----GYTMFWLTLSS
CCAPYIAMSSIDDYKNKA-RSQLRISG-LSPSAYWFGQ-ALVDVPMY-------------
---CLIFVFMYL---MSYSLSLQDGLNIYNLFGVIIWI-IQIPCTFGYATSLIFLTYVIS
FIFRKGKKNSGIWSFCFYII-----TILAVLGL-LF--DDSEH-SALYAIAFLIPQA---
--TLI--------GYLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2874)
VFHFS----------MF------YYLDEE-SRTIEPFLVSLI
PFLHFITFLFILRCLE-WKFGKTSMRKDPFF-RISPRRSDVCPNPEEPEG----EDEDVQ
MERRRTADALN-STNFD--EKPVIIASCLRKEYTGKRKRCLSKRK--KKIAAR
PF00005 // ENSGT00760000118965_1_Domain_5 (2874, 3037)
HVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSSG-------GD----PLGF
LGYCPQENALWPSLTVKEHLEVFAAVKGLRKADAA-----AAIAR----LVDALKLQDQL
KLPTKALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FKNTERGALLTTHYMAEAEAVCDRVAIMVSGRLRWVPVQAHAGSPGAQLAEFVAVKASAS
NREALEATPAHAESFSPSYYHPLPPSPRCIGAIQHLKNK-FGKNYLLEMKVKTPTQEETL
HSEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLAQAFFKLENVKQRFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDLK-EELHP-SVKWKLLPQEEP----------------------
ENSTSYP00000010482 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRCMNVSQQTWALLYKNYLKKWR-----MKA
QTLLEW
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
FFS-FLLVLFVY-LFPS---TLHYVRDSPQMLIT--DLGHVDT--FNDS-NYVI
AFAPESK------MAREIMDKVASAPFI------------------------------KG
ST--VMGWPDEKSMDTLDLNY-----SIDAVKVAFTDTL-SY----RLKFSWRHRIHKM-
---KE----HKNHSA----------------RCDAF---E-ETIMC-------EDLMF--
WEKGFVAFQAAINAAVIEIKTNHSVMEELMSITGINMKMLPS---------VAQGGLA--
TDFFIFFCIISFSAFIYNVSVNV-----------TQERQYMKSMMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGYILIVATLMAL----------IVKYAHVIVLTGFVMVFILFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTNIPVFLEWAFFLLSPFTFTIGMAQLLRLDSD---
------VDANAHSNSSHNPHLVIATFFILMLDTLLYLTLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1687)
YFDKVLPSD---YGRRRPP
LFFLKKSFWFQHQRT-HHVA--LENEIESDPA-SDDSFEPVSPEFRGKEAIRIKNLKKEY
------------T-RK------H-----------------------------GKVEAL--
--G--G
PF00005 // ENSGT00760000118965_1_Domain_3 (1687, 1840)
LVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTIYNHPLSEVAEL
ETVTK-LMGICPQS--NVQFGFLTVRE-NLRLFAKVKGILPQEVE-QEVRRALQELKMEN
IQDILAQNLSGGQSR-KLTFGIAMLGDPQV--LLLDEPTAGMDLLSQHRVWDLLRER---
---------------RSDRVILLSTQFMDEAD----------------------------
--------------------S---------------------------LADRKAFISNGR
LKYAGS--SLDLK---KKWGI---GYNL--SVHLN-E----------------------M
CDPESL-TSLVKQH--------------------IPDAKL----TAQSENKFVYI--LPL
ER--TNKFPDLFKDLDRCSNR---------GIENY--GVSIT----TLNEVFLKLEGK-S
TVDES-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSCCAP00000013469 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCRNFLMKWR-----MKR
ESLLEWGLS-ILLGLSVA--LFS---SGMKNVQFPGMAPQ--DLGRVDQ--FNSSSLM-I
VYTPVSN------LTQQIMNKTAHTPFL------------------------------K-
------------------------------------------------------------
--------------A----------------HCWDG---YG-GPWC-------TLTKY--
WNEGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
ALQTAINTAIIEITTNQPVMEELMSVTAITMKTLPF---------ISNDLLH--
NEIFILFSLLCFSPLVYFISLNV-----------TKERKKCKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-AGFIFIISIFITM----------IITLTQIVIMTGFMVIFVLFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLAV-----
FL-LTLCWGC--------MGFTVLYEQLPSSLEWILSICSPFAFTAGITQVIKLDYN---
------LNDLIFPDSSGDSYTMIATFSILLLDGLIYLLLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-RTDNKV--IEKEIELEHP-SGDYFEPVSPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLHFDIYESQITAILGHDGAGKSSLLNILNGLSVPTE--GSVMIYNKNLSEMQDL
EEIRK-ITGVCPQL--NVQFDTLTVKE-NLSLFAKIKGIHPQEVQ-QEVQRILLELDMQN
IQDSLAKNLSEGQKR-KLTFGIAILGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2296)
TTGLDPFSRDQVWSLLRER---
---------------RANRVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLYRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTENKKKLVYT--LPL
ER--TTTFPDLFSDLDKCCGQ---------GVTGY--DISMS----TLNEVFMKLEGQ-T
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVCAMAWL---------R
FLKLKRQ-TKVLLTL
PF12698 // ENSGT00760000118965_1_Domain_4 (2296, 2704)
LLVFGIATFPLIMENIIYAVLNE-NSDREFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGISY
N-GAIIVSGKQ-KDYR---FSIVCNTKRLHCFP-IL-MNIISNGLLQMFN----------
----------HTQH--IRIESSPFPVSHV-------------RLETGLPDGSIFLILVLC
STSPYITMGSISDYKKKA-KSQLWISG-LYTSAYWCGQ-ALVDINVF-------------
---ILILLSMYL---IVYIENM---QYL---YITSEIVFALAIVTPGYAASLVFLMYVIS
FIFRRRRKNSGLWSFCFFFA-----SINMFTIT-LI--NYFDL-SVLISTIVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFQTFLEMRD----------QPHQRELPD---AHFELSATDFLVSFI
PYFQALLFIFVLRCME-LKYGKKRMRKDPVF-RISPQIRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSNVD--EKPVIIASCLHKEYAGQKKSCCLKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LD------------H
LGYCPQENVLWPMLTVREHLELYAAVKGLRKGDAR-----LAIAR----LASAFKLHEQL
NVPVQKLAAGTT---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIKAV
VKNTERSVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-LGKNYTLELKVKEPSQVTLV
HTEILKLFPQAA--RQERHSSL--LIYKLPVADVYPLSQTFHKLESVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVENFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSANAP00000014657 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQRSVYQQTKALLCRNFLMKWR-----MKR
ESLLEWGLS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
ILLGLNVA--LFS---SGMRNIQFPGMAPQ--DLGRVDQ--FNSSSLM-I
VYTPISN------LTQQIMNKTAHTPFL------------------------------KG
SN--IIGAPNKTFMEEILLEN-----LPFAMGIIFNETF-SY----KLRVFQGYSIPLW-
---KE-----EDFSA----------------HCWDG---YG-ELWC-------TLTKY--
WNEGFVALQTAINTAIIEITTNQPVMEELMSVTAITMKTLPF---------ITKDFLH--
NEIFILFSLLCFSPLVYFVSLNV-----------TKERKKCKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITM----------IITLTQIVIMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LNLCWGC--------MGFTVLYEQLPSSLEWILSICSPFAFTAGMTQVIKLDYN---
------LNDLSFPDSSGDSYTMIATFSILLLDGLIYLLLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSHFQHQ-RTDNKV--IEKEVELEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--DLHFDIYEGQITAILGHDGAGKSSLLNILNGLSVPTE--GSVMIYNKNLFEMQDL
EEIRK-ITGVCPQL--NVQFDTLTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQI
IQDSLAKHLSEGQKR-KLTFGIAILGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLRER---
---------------RANRVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLYRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTENRKKLVYT--LPL
ER--TNTFPDLFSDLDKCCGQ---------GVTGY--DISMS----TLNEVFMKLEGQ-T
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVRAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAT
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIIYAMLNE-KSDREFKTELYFLSPGQLP--
QESRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDSISY
N-GAIIVSGKQ-KDYR---FSIVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IRIESSPFAVSHV-------------RFATGLPDGSIFLILVLC
STSPYITMGSISDYKKKA-KSQLWISG-LYTSAYWCGQ-ALVDVNVF-------------
---ILILLSMYL---IVYIENM---QYL---YITSEIVFALAIVTPGYAASLVFLMYVIS
FIFRRRRKNSGLWSFCFFFA-----SVTMFSIT-LI--NYFDL-SVLISTIVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFQTFLEMRD----------QPHQREFPE---AHFELSATDFLVSFI
PYFQALLFIFVLRCME-LKYGKKRMRKDPVF-RISPQIRNAKPNPEEPID----EDEDVQ
VERIRTAAALT-TSNVD--EKPVIIASCLHKEYAGQKKSCFLKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LD------------N
LGYCPQENVLWPMLTVREHLEVYAAVKGLRKGDAR-----LAIAR----LASAFKLHEKL
NVPVQKLAAGTT---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIKAV
VKNTERSVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-LGKNYTLELKVKEPSEVTLV
HTEILKLFPQAA--RQERHSSL--LIYKLPMADVYPLSQTFHKLESVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVENFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSSSCP00000021257 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHISVGRQTWALLCKNFLKKWR-----MKR
ETLLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WFFS-FLLALFAF-LFSS---NLHQVNDFLQLPAM--DLGRVDN--FNDS-NYII
AFAPESK------TIQEIMNKVASAPFM------------------------------KG
RP--ILGWPDEKSMDELDLNY-----STDAVRVVFTDTF-SY----HLKFFWGGRIPRM-
---KE----HRDHSA----------------HCQIM---D-EKATC-------ESSVF--
WEKGFVAFQAAINAAIIEITTNHSVMEKLMSVTGTNMKILPF---------VAQAGVT--
TDFFIFFCIISFSAFIYYVSINV-----------TQERQHIKALMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-TSFIFIMAVLMAV----------IIKSAPVVILTGFMVVFTLFFLYG
LSLITLAFLVSV----------------------------LVKKPFLT---GLVV-----
FL-LTVLWGS--------LGFTALYRHLPAFLEWTLCLLSPFAFTAGMAQLIHLDYD---
------VNANSHLDSSNNQYLIIATLFILVFDILLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YLDKILPTE---YGRQHSP
WFFLK-SFWFQHQSS-GHVA--LENEIDSNCS-SNDSFEPVSPEFQGKEAIRIRNLKKDY
------------VKGK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDVYEGHITALLGHSGAGKTTLLNILSGLSVPTS--GSVTIYNNKLSAVADL
ENLSQ-LTGVCPQV--NVQFGFLTVRE-NLRLFAQIKGIQPQGAE-QEVQRVLRDLEMEN
IQDILAQNLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2400)
AGSDPLSRHRVWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------L---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLK-E----------------------T
CDPDSI-TSLVKQH--------------------IPEAKL----AAQSEEKLVYI--LPL
ER--TNRFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DIGTW-GQL-QSDRT--------KDTGSLVELE----RVLSSFN--
----EPPKV-I-----------------------GGMALWRQQLRAIARV---------R
FLKLKTE-KRTLLTILLLFGVSFCPQLLEHLFYELYQK-SYSWGLSPNMYFLSPEEPP--
RAPLTHLLVI-----NK--TGS-SIDDFIYSLRQQDIALEVDALG----TRNG-PNESL
PF12698 // ENSGT00760000118965_1_Domain_4 (2400, 2769)
Y
N-GAITVSGDD-KDYR---FSVACNTKRLNCFP-VL-MDIISNGLLRIFN----------
----------SSEH--IQTDRSTYFEEHMS-------Y-EYGYL-----SNAFFWIPVAA
CFTPYIALSSIGDYKKKA-YSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYIFSPDEI-----IFIIQNLS-VQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLII-----TIFSIVAIDL---SEYGF-LGLFLCTILIPPF---
--TLI--------GSLFIFSEIS----------PDS------MDYLGASEQQIVFLALLI
PYLHFFIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFVLRCLE-MNFRKKSMRKDPVF-RISPRGSSVFPNPEKPDG----EDEDVQ
MERIKTANAVT-VPDSD--EKPVIIASCLRKEYAGKKRNCFARRK--KKVAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVL-LK--GSSG-------GD----PLGF
LGYCPQEDALWPSLTVKEHLEVFAAVKGLRKADAA-----AAIER----LVDALKLQDQL
KLPTKALSEGIK---RKLCFTLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FKNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAQVEAL
HREILRMFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-GEADL-SVKWKLLPGDP-----------------------
ENSCCAP00000004291 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTGALLCKNLLKKWR-----MKR
ESLLEWMNA-LVLLLCLY--TYP---HGHKVNDFSSLLTN--DLGRLDA--FNES-
PF12698 // ENSGT00760000118965_1_Domain_0 (597, 1541)
GFSV
AYTPVTK------TTQQIMNKVASASFL----------------------------A--G
KM--VLGMPDEESIKEFTANH-----SEDIVRVIFTNTY-SY----HLKFLLGHRTPSK-
---KE----HKDHTA----------------HCYRA---Y-EGVYC-------AVSEF--
WEEGFVVLQATINAAIIEIAANHSVMEELMSVTGKIMKIHSF---------ISQSGIV--
TDLFLFACIISFSPFIYYASVNV-----------ARERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALLLAL----------VIKSIQFIILSGFMVVFSLFLLYG
LSLIPLAFLMSI----------------------------LVRKSFLS---GLVG-----
FL-LTVFCGS--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNVFPHPSGGSNLIVATNFMLAFDTCLYLALV
ENSGT00760000118965_1_Linker_0_3 (1541, 1687)
IYFDKILPNE---YGRQRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDSDPS-SNDSFEPVPPEFHGKETLFVV-----L
FFFLSTSFSLPLYLIF------L-----------------------------SFPFFF--
--L--D
PF00005 // ENSGT00760000118965_1_Domain_3 (1687, 1840)
LIFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTVYNNKLSEMADL
ENLCK-LTGVCPQS--NVQFDFLTMKE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGTAILGDPLI--FLLDEPTAGLDPFSRHQVWNHLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCVGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVRQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIATL-GEV-QVEKA--------GDTEKLVELE----QVLSSLN--
----QMRKT-I-----------------------GGVALWRQQLCAIARV---------R
LLKLKHE-RKALLALLLILTVGLCPFLVEYIVMKMHQN-SYTLELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSLEHQKIALEVDAFG----TRNA-TDDPSY
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDVVSNGLLGMVK----------
----------PSVH--IHTERGTFLGNEQ-----SSPL---GFP-----AYIMFWLLLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LFPSAYWFGQ-ALVDVSLY-------------
---FLMFVFIYL---MSYVLEFEEI-----FV-AVIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TFFSVTGF-AF--DIFEI-EILFLFTFLIPLS---
--AMI--------GCLFMSYHLF----------LS------PFFGGE-PKNVQALLVFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDHFF-RIYPGSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STDFD--EKPVIIASCLRKEYAGKRRGCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSAG-------GN----DLEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKEDAE-----VAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNVAQVEPL
HAEILKLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQTFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGNFE-EDFDP-SVKWKLLPQEES----------------------
ENSMFAP00000040690 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS
PF12698 // ENSGT00760000118965_1_Domain_0 (550, 1542)
-FLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----QLKFLLGHEMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFSLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIPIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2719)
-VL-MDIVSNGLLGMVK----------
----------PSVH--IQTERSTFLENGQ-----DNPI---AFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NVFES-DIPFIFTFLIPPA---
--TMI--------GCLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
SSHLL----------FS------SLLSEE-RMDVQPFLVFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAK-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSPPAP00000017466 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLM-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTHMDEILLEN-----LPYAMGIIFNETF-SY----KLIFFQGYNSPLW-
---KE------DFSA----------------HCWDG---YG-EFSC-------TLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ITKNLLH--
NEMFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFVTI----------IITFTQIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILNICSPFAFTTGMIQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSMLLLDGLIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-RTNAKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGICPQF--NVQFDILTVKE-NLSLFAKIKGIHLKEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGITILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTENKEKLVYT--LPL
ER--TNTFPDLFSDLDKCSDQ---------GVTGY--DISMS----TLNEVFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLIFGIAI
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-RIDWEFKNELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLLMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFFIYMIS
FIFRKRRKNSGLWSFYFFFA-----STIMFSIT-LI--NHFDL-SMLITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEVRD----------QEHYREFPE---ANFELSATDFLVCFI
PYFQTLLFVFVLRCME-LKCGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTLREHLEVYAAVKGLRKADAR-----LAIAR----LVSAFKLHEQL
NVPVQKLTAGTT---RKLCFVLSLLGNSSVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGSL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKETAQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPMADVYPLSQTFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEIDT-TMRWKLLPHSDEP---------------------
MGP_SPRETEiJ_P0032170 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVRQQTCALLQKNLLKKWR-----LKR
ESL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1491)
MEWASS-LLLLLFLY--WYP---HGHEATDLSSVPTK--DLGRVDS--FRQS-EFMI
GYTPVTS------MTQQIMEKVAATPFM----------------------------A--D
KK--VLGLLDEENIKELTESH------AEIIRVIFSDTF-SY----HLKFQFDQRIPTS-
---RE----LRDHNA----------------HCDGL---Y-EEVNC-------LIAIF--
WKEGFVALQAAINAAIIETTTNHSVMEELLSVSGKFMKIHPF---------VRQEGIL--
TDFFIFTCIISFSPITYYVSINV-----------ARERKRMKGLMMMMGLQDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFIMALSLAL----------VIKSVQFFILTSFMVVFSLFLLYG
LSM---------------------------------------------------------
--------------------------------------------------
ENSGT00760000118965_1_Linker_0_3 (1491, 1682)
LLRVDYD---
------LNSNAPPDPASGSNLIIATNFMLVFDAFLYLALMMYFEKVLPNE---YGHQHSP
LFFLKSSFWLRTRKP-AHVI--LEDGIDPIPS-SDDSFEPVSPEFHGKESIRIRNISKEY
-------------KGK------P-----------------------------NKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENILR-IAGVCPQV--NVQFDFLTVRE-NLRLFAKIRGIPPQDVE-KEVQRVLLELEMKN
IQNILAQNLSGGQKR-KLTFGIAILGDSQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2296)
AGLDPFSRHRVWNLLKER---
---------------RADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGV---GYHL--SLQLK-E----------------------V
CVPENI-TSLVKQH--------------------IPAAKL----SAEGEGKLLYT--LPL
ET--TYRFPELCQSLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-A
AIDEP---------EVDIV-GEG-QTERS--------GDTERLMEME----QTLSSLR--
----ETEK--T-----------------------DGMALWRQQTCAIAKV---------R
LLKLKHE-RKTLLSV
PF12698 // ENSGT00760000118965_1_Domain_4 (2296, 2744)
LLILVVGICPFLFENISTEIRQS-SYTWELSPHDYFLAPGQQP--
QGMLTQLLII-----NK--TEA-SIDDFIHSVERQNIALEVDASG----ARDG-TDDPSY
N-GALIVSGNE-KNHS---FSFACNTKRLNCFP-VL-MDILSNGLLGMLK----------
----------PSAR--IQTERSTYLMDET-----IHPL---EDL-----WKTAFWLILTS
ACPPYIAMSSVTDYKNRA-WFQLRVSG-LFPSAYWVGQ-AMVDIPLY-------------
---CFVFLFMSL---MDYLFRFPDT-----MFSIITHV-IQIPCSVGYAISLIFLTYVIS
FISRKGKKNSGIWSLSFYII-----TVFSVAVI-LL--AFDVD-GTQYYIIFLIPPS---
--TLV--------GCLILSLHLF----------IG------QI
ENSGT00760000118965_1_Linker_4_5 (2744, 2873)
FKEE--QVIEPFLVFLI
PFLHVFIFIFTLRCLE-WKFGKKTMRKDPIF-RISPRNNDVYQNPEEPED----EDEDVQ
MERMRTANALV-STSFD--EKPVIIASCLRKEYAGKQKHCLSKKK--AKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEILGLLGHNGAGKSTSLKMISGDTKVTAGQVL-LK--GSRE-------GD----TPGF
LGYCPQENALWPNLTVKEHLEIFAAVRGLRKSHAA-----VAITR----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSILLLDEPSTG----LDPEG-QQQIWQAIRAI
IKNTDRGALLTTHYMAEAEALCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLEQVEPL
NTEILRLFPQAS--RQERYSSL--MAYKLPVEAVQPLSQAFFKLEKVKQTFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFELEELDS-SIKWKLLPQEEA----------------------
MGP_SPRETEiJ_P0032173 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKREINVCQQTWALLCKNLLRKKR-----LKR
DTF
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEFLYT-ALILLSLT--LFL---QMHEVYDFSSLPDV--DLGRIDS--FNDS-TFMI
VYTPITP------TTQRIMDRVSLVSYM----------------------------T--G
RK--ILASPNEENMTELISMR-----FSDVVGVIFTNAY-SY----NLKFIKGARIPTI-
---KE----HQDHTA----------------HCHSY---G-EIISC-------GLSEF--
WRDGFVALQAAINAAIIEVTTNHSVMEEMMSLTGKYIKIDSF---------VGQEGTT--
TDCFLFFCIICFSPLTYYISAGV-----------TRERKKMKGLMAVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVIVFVVTLLLTT----------IVKLVQFVFLTGLMVIFSLFFFYG
LSLISLSFLMSV----------------------------LLKKSFLT---DLVV-----
FL-LTVSCGS--------LGFTALYRYLPVSLEWLLSLLSPFAFMLGMVQLLRLDYD---
------VNSNA--DPMGNPNEVIGTIFMLFFDGVFYLLLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSK---SFHDKTY
WHACKSHFFLIDYSFYIRTA--LDNETDYE-F-SDDSFEPVSTEFHGKEAIRIRNLTKDY
-------------IQK------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTK--GWVTIHNNKLSEMTDL
ENISK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIQAHEVD-NEVQRVLLELDMKN
TQNILVQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2367)
AGLDPFSRHRVWNLLKER---
---------------RADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------IPDSKL----SAESEGKLSYI--LPL
ER--TNKFPDLYRDLERSPDL---------GIENY--GVSIT----TLTEVFLKLEGK-S
SIDQS---------DIGMT-EDV-QAGGA--------RSPERFAEVE----QLVSLLN--
----GRCKM-K-----------------------GGMALWWQQLCAVTRL---------R
FLKLKHE-RKSIVILILILGIGLLHILSANIYRMVRQS-DYCWELTPHMYFLTPGQQP--
QLPLTNLLIV-----NK--TGA-KID
PF12698 // ENSGT00760000118965_1_Domain_4 (2367, 2703)
DFIHSLEQQNIALEVDAFG----TRNG-TEDSQY
N-GAIILSGDE-KNYN---FTLACNTKRLNCFP-VL-VDIVSNGLLGLFA----------
----------PSAH--IQTDRSTFPEEND---HR--KF---NYV-----AYFFLWVLLMA
CVPPYISMTSIDDYKNRA-QFQLWISG-LSPSAYWFGQ-ALFEVPVY-------------
---CALILSIFI---ALYASAPPES-----KFTVGDLF-IQILYVGGYAMSVIFMTYVIS
FIYRKGRKNSGLWSLCFYIV-----SFFSMCFM-LF--DYFRD-TSLYVLTALVPPA---
--
ENSGT00760000118965_1_Linker_4_5 (2703, 2873)
TLG--------GCTLLHFENR----------E-----FSEII-FE-PEREYFYLFFLA
PLLHFAIFVVILRCME-RKLGMKTMRTDPVF-RISPRSDRVFNNPEDPDG----EDEDVS
QERVWTANALT-SADFQ--EKPAIIASCLRKEYKGKKKCFVLKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKMITGETKPSAGQVL-LK--GSST-------GD----TPGF
LGYCPQENALWLNLTVREHLEIFAAIKGMRKSDAN-----VAIER----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FSNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKEYLLEMKVKTPSQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFE-EELDP-SVKWKLLPQEEA----------------------
ENSOANP00000012832 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------CRNNLKEFLFLPNA------------------------------TD
AK--VIPVEDLETLDTYSQQN-----HSEIVGIIFKDTF-SY----QLKFSWGYRVPFT-
---DE----FIDHAA----------------HCTEY---EEEIFTC-------AISTF--
WNYGFIPFQASLNAAIIEVTTNHSVMKDLMSITGITMKVESF---------VAQHGVM--
YDFCIFFSVISFSPFTYFLSLNV-----------TRERKRLKELMKLMGLQDTA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGYVSIVATFLAL----------M--TSRLVYTTGFFTIFSLFILYG
LSLIALTFLLSV----------------------------LIRKPVLT---GLTV-----
FL-LTLFWGC--------LGILILYRKLPVSLEWILSFLSPFAFTAGMVQMILLDN----
-------------DPQGDSSLMMATFVMLLLDTVLYMALALYFDKLLPGD---YGHRHSP
LFFLKSWFWSPNP-RSGRVF--FENENNHIHS-SDDSFEPVSPEFHGKEAIRIKNIKKEY
-------------KKK------A-----------------------------GKVEAL--
--Q--GFQLDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSDPSE--GSATIYNYSVTERTDL
EEIRK-ITGVCPQF--SVHLDSLTVKE-NLSLFAKIKGILPGEVE-QEIQRVLMELEMKA
IQDTQGSSLNDGQKR-KLTFAIAILGDPQV--LLLDEPTSGLDPRSRLWLWNLLKCR---
---------------KSDRVIVLSTNCMDEAD----------------------------
--------------------V---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHVN-E----------------------T
CNSERI-TSLIQQH--------------------IPDAKL----AGRSEEKLVYT--LPL
ER--TDKFPGLYSDLDGCTDQ---------GIVNY--GVSMT----TLNEVFLKLEGK-T
AVDEA---------GPGIL-GQE-PGGDG--------RL----SESE----QASSRLP--
----EMKREVL-----------------------SGLALWRQQFRTVARI---------R
FLKLKCE-RRPLYILFFIVGISFLPLILEHLLLKIFFQ-PHVWPLNPGLYFLSSGQKP--
HAHLTHLLIL-----NN--TGS-PIEDLIHSLERQNIMLDVDDFA----SKNG-TYDPSH
N-GAIVVSRQE-MDYR---FSAVCHTKRMNCFA-VL-INIISNALLGILN----------
----------STEQ--IQIQRSNFVERDF-------------YLGFGTLESSFFWMLLAA
SISPYIGMSSIGDCKLKI-RSRLHLSG-LFPSAYWFGQ-AAVDMPLN-------------
---LVILLCMSA---PNYFLALNR---M---MLPTRIIFTLVACIIGCTASIVMFMYVVS
FMSRK-RSSSDFWCLCFFVI-----SLFSFMLF-LQ--FNFPS-ALMLSCIILVPFC---
--TLI--------GCTIFFFHLA----------IMYLEPPNLN-DDTYSENSDYFLLLLL
PCLHCLIFLFTLRCLE-AKEGKKMMTRDPIF-RIYPRSNSAYPSLGDPEG----EDDDVL
AERARTANALD-SSDAQ--EKPVIIASCLCKEYEVQKRNCFSKRK--KKVASRNVSFCVK
QGEVLGLLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3036)
STLLRMIVGETAPSAGKVI-LK--QNELVSGSVRGDK----ERRF
PGYCPQAEALWPDFTVREHLEVYAAVKGMTKEDTS-----AAITR----ISEALELQEHL
KVPVKKLSVGIN---RKLCFALSMLGNPTVILLDEPSIG----MDPKG-QQQMWQMILAT
CKSKENGAILSTHNMAEAEAVCDRVAIVVAGQL---------------------------
---------------------------RFIGSIQHLKSK-FGRDYVLEMKAKQPGQMEAL
HAEILRLFPQAV--RKERYSSL--IVYKLPMNDVCPLSSAFLKLEEVKQGFDLE---NYS
L-SQSTLEQV----------------------------------------------FLEL
TMEQDPGDFD-EELEP-TVKWKLLPSEDP----------------------
ENSCATP00000012490 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SVDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEFATNHSVMEQLMSVTGIHMKMLPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHMLSGMADV
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVFSSFH--
----ETKKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLAILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYLFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----VIFLIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-MNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EDEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSSG-------GD----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTEKGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFNP-SVKWKLLPQEEP----------------------
ENSFCAP00000039064 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVCQQTCALLCKNLLKKWR-----MKR
EPLMEWLSS-LLLLLFLY--EYP---IYHEAHDFSSLPSM--ELGPVGS--FNDT-TFAI
AFTPVTN------VTQQIMDKVALASFM----------------------------K--D
RE--VLGLSSEEDIQELRTHH-----LAEIIQVSFSNTF-SY----HLKFSLGYRIPTI-
---KE----HREHTG----------------HCFEM---STEEVSC-------QVSQY--
WEKGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
LALQAAINAAIIETTTNHSVMEELMSVTGKNMKIHPF---------VYQGGVA--
TDFFIFFCIISFSSFIYYASINV-----------TRERKEMKGLMRMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AVFVFIMALSLAL----------VIKSVQFVILTGFVAIFILFFLYG
LSLVTLAFLMSV----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRHLPTSLEWILSFLSPFAFTLGMAQLLRLEND---
------LNSNAFPDPSDYSNLIVATNFMLAFDLFLYMALTI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNK---YGHQYPP
LFFLKSSYWSRQPKA-DCVA--LEDEIHSDPS-SNDSFEPVSPEFHGKEAIRIRNVTKEY
----------K---GK------S-----------------------------GKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
DNISK-LTGICPQS--NVHFDFLTVKE-NLRLFAKIKGIRPHELD-KEIQRVLLELEMKN
IQNVLAQNLSGGQKR-KLSFAIAILGDPQV--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2382)
AGLDPFSRHLVWNLLKEW---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSGGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CVQEKI-TSLVKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TSKFPALYEDLDRCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AVDEP---------DIATW-GEA-PSERA--------GDTERLVETE----QVLSSLN--
----EISQT-I-----------------------GGMALWRQQICAIARV---------R
FLKLKHE-RKALLSLLLILGFGVCPLLTDIITMKVYQQ-SYTWELSPRLYFLAPGQQP--
RDPLTGLLII-----NK--TGA-SIDDFIHSVEHQNIALEV
PF12698 // ENSGT00760000118965_1_Domain_4 (2382, 2717)
DAFG----TKNA-LDDPSY
N-GAIIVSGNE-KCYR---FSLVCNTKRLNCFP-VL-MDIISNALLGMVK----------
----------PSAH--IQTDRSTFSRESQ-----RNSF---VFW-----EHTILWSILAS
SCTPYIAMSSFDDYKNKA-QSQLRISG-LFPSAYWFGQ-ALVDVPMY-------------
---FLILLLMYL---LDYGLNFQES-----AFVTINPT-IQILCSIGYAFSLIFLTYVIS
FIFRKGRKNSGIWSFSFFII-----ATFSLFLFMLL--DYFGY-GVLYYITFLIPQA---
--TLI--------GCM
ENSGT00760000118965_1_Linker_4_5 (2717, 2873)
FLFLSVS----------S---------------ATICPSVLELL
PFLHFIIFLFILRCLE-WKFGKTSMRKDPFF-RISPRSNNVYQNPEDPEG----EDEDVQ
MERVRTADALN-STNFD--ERPVIIASCLRKEYAEKRKHCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSRE-------ED----SLGF
LGYCPQENVLWPNLTTKEHLEVFAAVKGLRKADAA-----VTITR----LVDALKLQDQL
KLPVRTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQHMWQAIRAT
FKNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKNYLLEMKVKALEQRESL
HLEILRVFPQAA--RWVLAVNIKICIYELL---------MCTHLSAVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVRWKLLPQEDP----------------------
ENSMLEP00000019400 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-FLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HKDHTA----------------HCYET---S-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFGLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIIATNFMLAFDTCLYLVLAIYFEKILPNE---YGHRRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DVVFDIYEGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTVYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2470)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AINES---------DIAIL-GEV-QVEKA--------DDTESLVEME----QVLSSLN--
----KMGKT-I-----------------------GGMALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
---------
PF12698 // ENSGT00760000118965_1_Domain_4 (2470, 2719)
-PSVH--IQTERSTFLENGQ-----ANPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNVEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TVFSVAGF-AF--IVFES-DIPFIFTFLIPPA---
--TMI--------GCLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
SSHLL----------FS------SLLSEE-RMDVQPFLVFLI
PFLHFVIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVRQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSPPAP00000014398 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMALASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEMVGVIFSDTF-SY----RLKFNWGYRIPVI-
---KE----HSEYTE----------------HCWAM---HGEI-FC-------YLAKY--
WLKGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
AFQAAINAAIIEVTTNHSVMEELTSVIGINMKIPPF---------ISKGEIM--
NEWFHFTCLVSFSSFIYFASLNV-----------ARERGKFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-ICFIFIMSIFMAL----------VITSIPIVFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFTAGMAQITHLDNY---
------LSGVIFPDPSGDSYKMIATFFILAFDTLFYLIFTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1687)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINPEHS-SDDSFEPVSPEFHGKEAIRIRNVIKEY
-------------NGK------T-----------------------------RK------
-----S
PF00005 // ENSGT00760000118965_1_Domain_3 (1687, 1840)
IFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSATIYNTQLSEITDM
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2399)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNKFPDLYSDLDKCSDQ---------GIRNY--AVSMT----SLNEVFLNLEGR-S
AIDEP---------DFDIG-KQE-KIHVT--------RNTGDESEME----QVLCSLR--
----ETRKA-V-----------------------SSAALWRRQIYAVATL---------R
FLKLRRE-RRALLCLLLVLGIAFIPIILEKIMYKVTRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLIV-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRKG-SDDP
PF12698 // ENSGT00760000118965_1_Domain_4 (2399, 2750)
SY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNYFP-VL-MGIVSNALMGIFN----------
----------FTEL--IQTESTSFSRDDI-------------VLDLGFIDGSIFLLLITN
CISPFIGMSSISDYKKNV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILFSIHL---IYYFIFL----GF---QLSWELMFVLVVCIIGCAVSLIFLTYVLS
FIFRKWRKNNGFWSFGFFII-----LICVSTIM---------------------------
---------------------LD----------F--MRNLDSLDNRINE
ENSGT00760000118965_1_Linker_4_5 (2750, 2883)
VNKTILLTTLI
PYLQSVIFLFVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANALT-APNLE--EEPVITASCLHKEYYETKKSCFSTRK--KKIAIRNVSFC--
--
PF00005 // ENSGT00760000118965_1_Domain_5 (2883, 3037)
EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVV-LQ--GSRA-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGTLLTTHYMSEAEAVCDRMAMMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGRDYLLEIKMKEPTQVEAL
HTEILKLFPQAA--WQERYSSL--MAYKLPVEDVHPLSRAFFKLEAMKQTFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQELGNVD-DKIGT-TVQWKLLPQEDP----------------------
ENSMLEP00000032889 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEVVGVIFRDTF-SY----QLKFNWGYRIPPI-
---KE----HTEYTA----------------HCWAM---HGEI-FC-------YLAKY--
WLNGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFIFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFIAGMAQITHLDNY---
------LSGVIFPDPSGDSYIMIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHDGAGKSTLLNILSGLSVSTE--GSTTIYNTHLSEITAM
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2514)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GVSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVFLE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNIKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSHDDI-------------VLDLGFIDGSI
PF12698 // ENSGT00760000118965_1_Domain_4 (2514, 2770)
FLLLITN
CISPFIGMSSISDYKKKV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWELVFVLVVCIIGCAASLIFLTYVLS
FIFRKWRKKNGFWPFGFFII-----LICVSTIL-VS--TQYET-PNLILYMIFIPSF---
--TLL--------GYIMFLIEFS----------LMYMRNLDSLDSRINEVNKTILLTTLI
PYLQSLIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLT--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMITGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQIWQILQAT
IKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVEAL
HTEILKLFPQAA--RQERYSSL--MVYKLPVEDVHPLSRAFFKLEAVKQAFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSDNOP00000007494 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MKKKDKNVCQQTQALLYKNFLKKWR-----MKR
EILVELGLP-LLLGLNMG--LIS---FFRENVKVTEIPPH--DLGRVDK--FNSSSVK-V
VYTPISN------ITQQIMNKTAFSPFW------------------------------KG
RE--VTGVRCSSDLDRQVLTS-----CRKVRGARDNVVKLAS----EIMCLGQY-GDSC-
---MG-----ERLIA----------------HCWKG---YD-MFSC-------LLAQY--
WERGFVTLQTAIDSAIIEVTTNHSVMEELMSVTGTNMKTSPF---------ISKDPFM--
YEMFIFYCLLYFSPFIYFSSLNI-----------TKERKSLKDVMKIMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLFY-AGFIFIICILIAI----------VITSAQIIVMTGFMVIFTLFFLYG
LSLITLVFLMSV----------------------------LLKKTVLT---SLIV-----
LL-FTLFWGC--------VGLTALYRQLSSTLEWILSICSPFAFTAGLAQILHLDYK---
------VNGIIFPDPSGDSYMMIATFFILAFDALLYFVLALYFDRLLPYG---SDHRYSP
LFFLNSSSCWQHQ-RTDDKV--FENEIDTEHP-YGDYFEQVAPEFQGKEAIRIRNVRKEY
-------------KGK------S-----------------------------GKVEAL--
--K--GFIFDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLNILNGLSVPTE--GSVIIYNRNLSEMHNL
EEIQK-ITGVCPQF--NVQIDVLTVKE-NLRLFAKLRGIQSQEVE-QEVQRILLELDMQN
IQDNLAQNLSEGQKR-MLTFGIATLGDPQL--LLLDEPTAGLDPFARHRVWNFLMER---
---------------KADCVILFSTKFMDEAD----------------------------
--------------------I---------------------------LADRKMIMSNGR
VKCAGS--SLFLK---RKWGL---GYHL--SLYRN-E----------------------I
CESEKI-TSFINQH--------------------VPDAKL----KTENEEKLVYT--LPL
ES--ANTFPDLFSDLDKCSSL---------GVMNY--DVSIS----TLNDVFMKLEGK-P
TTEQD----------------ER-IRLKS--------SKTFSSSQTE----TLYPLMA--
----IVNNA-V-----------------------MSTGVQISAKCILSML---------W
GIYLEKSFVVFLLLTLLVLGIAVFPLIVENIFYITLYQ-KSDWEFKPELYFLSLGQPP--
RDSRTSLLIV-----NN--TES-NIEDFICSLKHQNIVLEVDDFE----NRNG-TNDLSY
N-GAIIVSGQQ-KDYK---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTEH--IRIARGTLPLYHV-------------LFLTGLPEGFIFLYLVTC
SIAPYLAMSSVNDYKRKA-QFQLWISG-LYPSAYWCGQ-ALVDLNLY-------------
---AFILLSMHL---VFFLEDL---EHI---HITSRMVFAVVVITFGYAASLVFLTYVIS
FVFGKRRKNSGLWSFCFYMI-----SVFTVSFV-IA--HHFDK-SVIIACMVLIPIY---
--TMG--------GFLTFLIEKA----------YRPFNKFQD---PNHDLNEVDLLVCLI
PYFQTMILIFILRWLE-IKWGKKTTRKDPVF-RISPQIRGGRPNPEEPVD----EDEDVQ
EERIRTATSLT-TSNDD--ERPVIIASCLHKEYASKNKSCCSKRK--KKVAARNISFCVR
KGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSTIRMVSGVTRPTAGEVE-LK--GYSSV-SGHQEED----MVKF
LGYCPQENALWPRLTVREHLEVFAAVKGLRKAAAQ-----AAITR----LVNAFKLQEQL
KVPVQKLTAGSA---RKLCIVLSMLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQTS
IKNTERGALLITHYMAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FAKDYILELKVKEPSQITLV
HTEILKLFPQAA--QQQRCSSF--LAYKLPMTDVHPLSQAFQKLETVKHNFNLE---EYS
L-SESTLEKV----------------------------------------------FLEL
SKEQEVESFD--QVDT-TMRWKLLPHSDNL---------------------
ENSAMEP00000010998 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHIKQKSVYQQTQALLCKNFLQKWR-----MKR
ESLLEWALP-ILLGLYMG--LFS---HFRENMYFPGLPPQ--DLGGADN--VNNS-LA-I
VYAPISD------LTQQIMNKTTFA-LL------------------------------KE
RR--IIGVPNQKSMDKILLDN-----ITGIAGIVFNDTF-SY----KLKFFPGYYIPFL-
---KE-----DLFAA----------------HCWNM---DD-GHSC-------SLSKY--
WSSGFVALQAAINAAIIQITTNHSVVEELMSLTAVNMKTLPF---------IYKGVLQ--
KELFIFYCLLYFFPFIYFVSLNV-----------TKERKKCKEFMKMMGLQGSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSCGLIY-AGFTFIISMMITV----------IITSTQIIVMTGFTVIFTLFFLYG
LSLITLTFLMSV----------------------------LLKKTLLT---NLAL-----
FL-LDAFCGG--------VGFTVYYRQLPSSLEWIFSICSPFAFTAGMSKIIYLDNT---
------MNGIIFPDPSGDSYVMIATFSILAFDALFYLALALYFDKILPYG---DEHHYSP
LFFLNS-SCFQHQ-RTNNKV--IEKEIDPEHP-SEDYFEPVAPEFQGKEAIRIRNVKKEY
-------------TGK------S-----------------------------GKMEAL--
--K--DLLFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAVLGHSGAGKSSLLNILNGSSVPTE--GSVTIYNKNLSEMQDL
EETKK-ITGVCPQF--NVQFEVLTVKE-NLRLFAKIKGIQPQEVE-QEVQRILLELDIQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEPTAGLDPFSRHRVWSFLKEH---
---------------KAGRVILLSTNLMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---RKWGL---GYHL--SLYRN-E----------------------V
CDPEKI-TSFINHY--------------------IPDAKL----KTENKEKLVYT--LPM
ER--TNKFPDLFNDLDKCSGQ---------GVTSY--DISMS----TLNDVFMKLEGK-S
TIEQD----------------FE-QAE-I--------RDTESLHEIE----PACSSFP--
----EMQKA-V-----------------------SDMGLWKMQVCTIARL---------R
FLKLKRG-RRELLILLLVFGIAIFPLIVEKILYALLIQ-KSDWEFKTELYFLSPGQPP--
EDPRTSLLVI-----NN--TES-NIEDFIQSVKHQNILLEVDDFA----NRNG-TDDLSY
N-GAIIVSGKQ-KDYR---FSVACNTLRLHCFP-IL-VNIISNGLLRMFN----------
----------GTQN--IRIERSPYPFNYV-------------FFWMGLPEASMFLFWVVC
SFSPYIAMSSISDYKKRT-KSQLWISG-LFPSAYWCGQ-ALVDISFF-------------
---IFLLLSMYL---IFYIANI---TEI---NITSGIVFGLVVFGLGYAASLVFLTYVIS
FIFRKWKKNSGLWSFCFYIT-----SIIMFDIM--L--IHFNL-PTLISSMVLVPSA---
--TMG--------GFLAFLAQRA----------YEHQRKYPD---HRYDPSGVDLLVCLI
PYLQALIFVFILRCME-TKCGKKIMRKDPVF-RISPQHRGSRPNPEELVD----EDEDVK
AERQRAATALS-TSHAG--EKPVIIASCLHKAYAGQKKSCFSKRK--KKIATRNISFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEILGLLGPNGAGKSSSIRMISGITKPTAGEVVELK--GCGSV-WGHQGDN----TVNF
PGYCPQENVLWPNLTVREHLEVFAAIKGLRKEDAT-----IAISR----LVDAFKLHKQL
NVRAQKLPEGAT---RKLCFVLSILGDSPVLLLDEPSTG----MDPAG-QQQMWQMIQAS
IKNTEKGALLTTHYLAEAEAVCDRIAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELRVKEASQVTWV
HAEILKLFPQAA--QQERYSTF--LVYKLPLADVYPLSQTFRKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELGNFE-EEIDT-TMRWELLSPSDDF---------------------
ENSMGAP00000006958 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------QRNLSVFQQTKILLWKNVLIKWR-----MKM
QSFQEWMLS-LLFLPLMF--IVSN--FMMY-IPYPEVPRS--HLGQLDDPAYNAT-GVTI
AFTPVTA------ATRHIMNTVASKSVM------------------------------TG
IK--LEALETERALEEAWILN------QEIIGVVFKNNF-SY----HLRFSAENVVF-P-
---NE----NLEYID----------------TCYN----YS-EHYC-------ESPKY--
WYQGFLSLQSSIDAAIIEVVTNHSVWEEMRTIAGVRAKSRSV---------ISSITLE--
YIYFMITIVMCFSSFMYFLSVNV-----------VREKKKLKVLMKLMGLHDMA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-AIYVLVLSCLLTA-----------LVVQESFYTSSFSAILLLFFLYG
LACVHLVFMLCS----------------------------LLRTSKLV---GSLG-----
FL-ITFLFGC--------LSLSVLIENLPEPLKWFLSLFCPFAFNVGIAKIFSLERY---
------GIGFSFSNIMEESYFLLSTYIILTFDSVLYMLLAIYFDKVLQGK---YGIPAPP
LFCLKPSYWMRSRRG-FPGE-GHRGAGSLEEP-PGDDVEPVPLEFRGKEAIRLHNIKKTY
-------------KKK------D-----------------------------KKTEAL--
--R--GLSLNIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNVLSGLTLPSE--GSATIYDYKLSEIGDR
EEIRE-MVGVCPQF--DTQFEVLTVKE-NLQTFAEIKGIKSKEVE-QEVQNILELLDISS
VQDTQAEKLSGGQKR-KLSIGIAMLGNPQV--LLLDEPTAGLDPLSRHQVWSLLKEH---
---------------RDGRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAFISRGR
LKCVGS--SLFLK---NKWGI---GYHL--RIHVS-D----------------------S
CDVENV-TSLVKQY--------------------IPSVML----LGHGQYELRYK--LPL
EN--VNKFPDLFRGLDSCSDL---------GIINY--GVSMT----TLEDVFLRLEEA--
AVDQEDKC---------VP-G-E-RAEGG--------A--RSPEEME----SGSLLLS--
----DTGRVTV-----------------------SCWALWRQQVSTMAWV---------R
LLKLKSS-VKNLLSILLLYVVFLLPLILQLSLTTIWES-MSAWELCSSRYFLPLRTRA-H
-ADTTNLLVL-----NS--TGS-GIEDFIHALESQDLAVEITNKE----N---ITEELKY
N-GAIKVSCSL-KSYR---FTIFCHMEAINCFP-VL-VNIISNALLRAFN----------
----------STAH--IRIWSHPFYST-----------DHEQYWDSFVPFYLIYMLLLFP
GFPPHFAMGYLQDYKT-GARAQLRVSG-LFPSAYWCGQ-ALVDVPFC-------------
---WLLLFSMFG---LQFAISNR-------VSGTFGSFFLLIMNVFGYGVSIIFLIYFIS
FFFRKGW-NCDFWSFILIVV-----CLVTFIIGRVMDYAIELE-ISLYLLSLLIPMY---
--PPL--------ALMLNIE------------QIFIEDSNITEGFPNNNILIAVFAVRKY
PYIHSVVFVFLLRYLE-IKYGRPVLRKDPIF-RISPRKENSHQHPEDPE----EEDEDVK
AEREAVKNAIA-APRQE--EKSVIIVSNLYKEYKIKKAGSVFRKK--KKMATKNISFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGPNGAGKSTVIKMIAGETTLTAGQVL-LR--SRDATLC-WTQDH----VPAY
LGHCPQEDPLWPDLTVHEHLKVYAAVKGVHKEDIA-----TAINR----IVNALELQDYL
KKPTRKLPAGIT---RKLCFAVCMLGNPSVLLLDEPSTG----MDPNG-QRCVWKMIRAA
LKTQETGAVLTTHYMEEAEAVCDRVAILVAGQL---------------------------
---------------------------RCIGSIQYLKNK-FGKGYLLEIKVKDPETTDLL
HAEILRIFPSAA--RQERFPSL--LVYKVPMEDALPLSQSFSKLEEAKQNFNLE---EYS
F-SLNTLAQV----------------------------------------------FLEL
SREQEKENFD-LTLDG-PFEWKQLQQEDS----------------------
ENSCGRP00000024501 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVNREINVCQQTWALLCKNLLRKRR-----MKR
DTFLEFLYT-SIILFSLS--LTT---EIHEVYDFSHLPNV--DLGR
PF12698 // ENSGT00760000118965_1_Domain_0 (587, 1542)
IDS--FNDS-NFMI
AYTPVTH------TTQGIMDKVSLASYM----------------------------A--G
IT--VLGFPDEENMTELVSSR-----YHDVVRVIFTNTY-SY----HLKFHTGTRMPSK-
---KE----HGDHTA----------------HCSTY---E-DNINC-------GISHF--
WTEGFVALQAAINSAIIEVTTNHSVVEEMMSVTGKYMKIDTF---------IGQGGVV--
TDSFLVFCIICFSPLAYYISAGV-----------TRERKKMKGLMTVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GAIIFVVSLLLTF----------IIKLVQFVILTGFMAIFSLFFFYG
LSLISLSFLMSV----------------------------LLRKSFLT---DFVV-----
FF-LTVFCGS--------LGFAALYRILPGSLEWVLSLLSPFAFMLGMAQLLHLDYD---
------VNSNA--DPTGNPNVIIATIFMLFFDSVFYLVLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSE---YGQRHSP
LFFLKPSFWSQQNQVLDY-------EIDSE-F-LDDSFEPVSSDFHGQEAIRIRNLTKEY
-------------TER------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-A--DLSLDIYKGQITAILGHSGAGKSTLLNILSGLCAPTK--GWVTIYNNKLSEKTDL
ESIIK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIRKHEVD-NEVQRVLMELEMKN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2503)
AGLDPFTRHRVWNLLKER---
---------------KAGRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CVPERI-TSLIKQH--------------------IPDSKL----SAESEGKLSYI--LPL
ER--TNKFPDLCRDLERCPDL---------GIENC--GVSIT----TLSEVFLKLEGK-S
TIDQS---------DLGMS-EDV-QTERT--------RGTGRPTEME----QLVSLLT--
----EKTNM-K-----------------------VGLALWWQQLCAVARL---------R
FRKLKHE-RKSFVFLILILGIGLLHILSANIGMIARVS-DYCWELSPHMYFLTPGQQP--
HEPLTNLLII-----NK--TGA-QIDDFIHSLEKQNISLEIDAFG----TRNG-TEETLY
N-GAIILSGGE-NSFK---FTLACHTKRLNCFP-VL-VDIVSNGLLGLFT----------
----------PSAH--IQTDRSTFPEDDT---RG--PF---D
PF12698 // ENSGT00760000118965_1_Domain_4 (2503, 2703)
YV-----PYFISWILFMA
FVPPYISMTSIDDYKNGV-QLQLWISG-LCPSAYWFGQ-ALVEVPIY-------------
---YILSLSMCV---AFYASAPQET-----MLTTKDLL-FQILYVGGYAMSIIFMTYVIS
FLFRKGRKNSGIWSFCFYIV-----ALCSILLI-FT--DYFLD-DLLFCIIALIPPA---
--
ENSGT00760000118965_1_Linker_4_5 (2703, 2873)
TLV--------GCTMLHFQYC----------A-----LCDIG-LEEATSDYTFLLFLV
SFLHFAIFLVILRCLE-SKLGMKTMRMDPVF-RISPRTDRVFNNPEEPEG----EDEDVR
LERERTANALT-SVDFQ--EKPAIIASCLRKEYKGKKKCFVPKSK--KKLAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKIITGEAKPSAGQVL-MK--GSSR-------GD----TLGF
LGYCPQENALWPNLLVREHLEIFAAVKGMSKGDAA-----VAIAR----LADALKLQDQM
RAPVKTLSEGVK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVRIPAQVEAL
NAEIKRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDCFE-DELDP-SVQWKLLPQEEA----------------------
ENSRNOP00000072754 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRRLRLGQQMWALLCKNWLRKFR-----MRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLLEWLLS-FLLILLAY-QLSS---NLHQVHDAPEMSMM--DLGRVDD--FNDS-NYII
VFAPESE------TTHEIMNIAALAPFM------------------------------KG
RT--IVACPDESSMSELNLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPKT-
---KE----HKDHTA----------------PCEPF---K-NKMVC-------ENSVF--
WEKGFVAFQTAINAGIIEVTTNHSVMEELMSVIGSVMKMQPF---------IAQGGVA--
TDFFIFFCVISFSSFIYYLSVNV-----------TQERQSITTLMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILVVATLMSL----------IVKSTQVVVLTGFMVVFLLFLLYG
LSLITLSFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTVFWGS--------LGFTALYKHLPAFMEWILCFLSPFAFINGMAQLIHLDYD---
------VNSNVNLNSPNNSYLILATLFMLVLDALLYLALAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKILLSK---YGHQRSP
LFFLKSSYWFQRRGA-DHVV--LENEIDSAPS-LNDSLEPVSPEFQGKEAIRIKNLRKEY
------------T-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINTLSGLSPPTT--GSITIYNQTVSETEDS
YAVPK-LTGVCPQS--NIQFGFLTVQE-NLRLFAKIKGILPQEVE-QEVRQVLRDLEMEN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2404)
AGLDPLSRHHIWNLLKER---
---------------RSGRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------T
CDPESI-TSLVKKH--------------------IPDARL----TAQSDEQLVYI--LPL
ER--TNKFPDLYRDLDRCSNH---------GIEDY--DVSMT----TLNEVFLKLEGK-S
MAEEP---------DAGVC-GRL-LSDGA--------KDVESLVELE----RVL-PLD--
----SSGSS-V-----------------------SGMALWRQQLCAVAKV---------R
FLKLKNE-RRSLMTMLLLFGISFVPQLLEHLVYKVYHK-SYSWGLSPSMYFLSPGQLP--
QDPLTHLLVI-----NK--TGS-SIDNFIHSLRQQGIALDVDALG----TRNG-KEEALY
N-G
PF12698 // ENSGT00760000118965_1_Domain_4 (2404, 2771)
AVTVLGDE-KDLR---FSVACNAKRLNCFP-VL-ADILSNGLLGIFN----------
----------SSER--IQTDRSTVFEDHML-------Y-EYGFM-----SNAFFWIPVAA
SLTPYIAMGSISDHKKKV-LSQLWTSG-LYPSAYWCGQ-ALVDIPIY-------------
---FLILLLIRA---NISSFQSESF-----VFVFFNLI-IKIPCSIGYASSLIFLTYVIS
FVFRNGRKNSGIWSFFFLIV-----TIFFIVATDI---NEYGF-LQLLFCTLLIPPF---
--TLI--------GSLLIFSEVS----------YDS------VDYLGSSESQLVFLALLI
PYLHFLLFFF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-RYIRKKTLRVDPVF-RISPRSCRAFPNPEDPGE----EDEDVQ
MERVRTSGAMT-TPQMD--EKPVIIASCLRKEYTVKTKRCFSKTK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTVPTAGQVF-LK--GSSG-------SA----ALGF
LGYCPQENVLWPNLTVKEHLEVYAAVKGLRKKEAI-----VTITR----LVNALKLQDQL
KALVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKLKTPALVESL
NTEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSEAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFD-EEGSS-SVKWKLLPQEEL----------------------
ENSSTOP00000011919 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRIKQTSVYQQTQALLCKNFLKKWR-----MKR
ESAL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLP-ILLGLYVG--LLS---EVRENNQLPEIPPQ--DLGRVDK--FNVSSIM-I
VYTPVSN------ITQQIMNTTAFAPLM------------------------------KG
TR--IIGVPNEKDMDDVIFQN-----FPHAVGITFSDTF-SY----KLKFFQGYAVPFL-
---RD------DLTG----------------HCWEI---YG-EYSC-------VLSKY--
WERGFVTLQTIINAAIIEVTTNHSVIDELMSVTAINMKTLPF---------ISKDIFQ--
SEMFILYCLLYFSPFIYFVSHNV-----------TKERKKSKELMKMMGLHDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-TAFILVLSIVITI----------IITSTQVILMTGFMVIFTLLFLYG
LSLLALSFLMSV----------------------------LLQKAVLT---NLFV-----
FL-LTLFWGF--------VGFTAFYKQLPPSVQWILSICSPFAFRVGMTQILHLDYN---
------LNGVVFPDPSEKSYTMLATFSVLAFDGLIYLMLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NEHRYSP
LFFLSSSSCFRHR-RTDNRV--IEKDLDPEHP-SDGYFEPIASEFQGKEAIRIRNVKKEY
-------------KTK------S-----------------------------GQVKAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GVLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRQ-ITGVCPQN--NVQIDMLTVKE-NLSLFAKIKGIRPQEVE-QEVQQILLELDMQN
IQDNLAIHLSDGQKR-MLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2304)
AGLDPFSRHQVWTFLKER---
---------------RVNRVILFSTQSMEEAD----------------------------
--------------------I---------------------------LADRKVIMSNGE
LKCAGS--SVFLK---RKWGL---GYHL--SLYKN-E----------------------I
SDPEQI-TSFINHH--------------------ISDAKL----KLENKEKLVFT--LPL
ES--TSKFPDLFSDIDKCSGQ---------GMMSY--DISMS----TLNEVFMNLERK-P
EIRQD----------------FE-QTDKI--------RDSESPSEMD----PACSSLP--
----EVHKS-V-----------------------SDMSLWRMQVCAIARL---------R
FLNLKRG-RKTLLTLLLVFGIAL
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2759)
FPLIMERVANSLINE-SANWEFKTELYFLSSGQLP--
QEPRTSLLII-----NN--TES-NIEDFIQSLKHQNILLEVDDFE----NRNG-TEGLSY
N-GAIIVSGKQ-KDYR---FSIVCNTKRLHCFP-IL-MNIISNGLLWMLN----------
----------YTQY--IRIERSPFNLNHL-------------YIWTGLPDGAPFIFFIVC
CLSPYIAMSSVTDNKKKA-SSQLWISG-LYPSAYWCGQ-ALVDVNLF-------------
---NLILLLMYL---IIYIANK---MGI---SVTSQGIFAMVVVSLGYSASLIFLTYVIS
FIFRKRRKNSGLWSFCFYVV-----LTVMPYII-LI--SDFNI-TVIIVSMVLLPSS---
--TLE--------VFLLFLSKRA----------QEYHEEFQE---FKFHLSAVDLLVC
ENSGT00760000118965_1_Linker_4_5 (2759, 2873)
LI
PYIQALLLVFILRCME-LKCGQKVMRKDPVF-RISPQIQNVPLNPEIHVDED--EDEDVQ
AERMRTSSALT-TSNVN--ENPVIIASCLHKEYAGQRKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGPNGAGKSSSIRMIAGITKPTAGQVE-LRVGECKSF-LGQQGDD---M-VKF
LGYCPQENVLWPTLTMKEHLEVYATVKGLQKEDAA-----IVISR----LVNAFNLYEQL
NVPVQKLASGTT---KKLCFVLSILGNSPILLLDEPSTG----IDPTG-QQQIWQAIQAA
VKSTERSVLLTTHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILELKVKEPSQIPLV
HTEILNLFPQAA--QQERFSSL--LTFKLPIADVYPLSQAFYKLETVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
FSRPELGNVD-EEVDT-TMRWKLLSYSDEP---------------------
ENSHGLP00100011409 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHICVHQQMWTLLCKNCLKKWR-----MKR
ETMLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WLLS-FLLVLFAF-LFSS---NLHQVNDSSQIPAM--DLGRVDS--FNAS-NYII
AFAPESK------TTQEIMSKVASAPFM------------------------------KG
RT--IMGWPDEKSMTELNLNY-----STDAVRVIFNDMF-SY----HLKFSWGHRIPKI-
---KE----HKDHSA----------------HCQAV---D-EKITC-------ESSMF--
WEKGFVAFQAAINAAIIEIAVNHSIMEELMSITGVNMKILPF---------IAQGGIT--
TDFFIFFCIISFSSFIYHLSVNV-----------TQERQYIKSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGFMY-AGFILVMAVLMAL----------IVKSTQIVALTGFMVVFILFFLYG
LSLITLAFLMSM----------------------------LIKKPHLT---GLAV-----
FL-LIIFWGS--------LGFTALYRHLPAFLEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNVHLDASNNSFIIIASFYMLVFDALLYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTQ---YGQHS-A
MFFLKSPFWCKYQRT-DHAV--LENEIESDPS-SNDSFELVPAEFHGKEAIRIKNLKKEY
------------K-GQ------C-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDIYEGQITVLLGHSGAGKTTLLNLLSGLSLPTS--GSITIYNHTLSEMADF
ETVSK-LIGVCPQS--NVQFGFLTVKE-NLRLFAKVKGILPHEVE-QEVQQILRYLEMEN
IQDILAENLSGGQKR-KLTFGIAILGDPQV--LLLDELTAGLDPLSRHHLWNFLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVLISHGR
LKCAGS--SLFLK---KRWGI---GYHL--SLHLN-E----------------------M
CDPKSV-TSLVKQH--------------------IPDAKL----TEQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCPNK---------GIENY--GVSMT----TLNEVFLKLEGK-S
TIDES---------DIASW-GQS-QSDEI--------KDMASLVVLE----QVLSSLH--
----VKRKI-A-----------------------GGMALWRQQLCAIAKV---------R
FLKLKNE-RKSLLAILLLFGISFFPQLLEHLFYELYQK-SYSWELSPNIYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-SIDNFIQALGRQNIALEVDAFG----IRNG-TEELSY
N-GAITVSRDK-EDHR---FSIACNTKRLNCFP-VL-IDIISNGLLGTFN----------
----------STEH--IQTDRSTFFA----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSPEMP00000000137 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSMKEISVYQQTRALLHKNLLKKWR-----TKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
FLEWSIP-IIIGLYMG--LFS---YIKVNIQVPEVPPQ--DLGSLDE--FNGSSIV-V
VYTPISN------ITQQIMNKTTFAPSM------------------------------KG
TR--IIGVPSKNDLDEVLLKN-----FPHALGIIFNDTF-SY----KLEVFLTHGNPFL-
---K------EDLLA----------------HCWDV---YD-GVSC-------SLSRY--
WKRGFVPLQSAINAAIIEITTNHSVMEDLMSVNAINMKTLPF---------ITKDVFQ--
YEVFILFCLLYFSSFIYFVSRNI-----------TTERKKYKELMKIMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIISILIAV----------IITSAQIVVMTGFLVIFTLFFLYG
LSLIAVTFLVAV----------------------------LLQKAILT---NLIV-----
FL-FTFLWGC--------VGFTVLHKQLPTSLEWILSICSPFAFTSGMAKIISLDYN---
------LNGVVFPDSSGESYVMLMTFSILAFDGFIYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---DERRHSL
LFFLNSSSCFR-QKTSSNKV--IERGIDSELP-SDDYFEPVAPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------VKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFFDIYESQITAILGHSGAGKSSLLNILSGLYVPTA--GLVTVYNKNLSEMQDL
KEIRK-ITGVCPQH--NVQFDALTVKE-NLTLFAKIKGILPQNVK-QEVQQIILELDMQN
IQDNLAEHLSEGQKR-KLTFGIAILGDPRI--LLLDEPTVGLDPFSRQRVWSFLKER---
---------------RANRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGS
LKCMGS--SMFLK---RKWGL---GYHL--SLFMD-E----------------------T
CDSEQI-ASFINLH--------------------IPDAKL----KAKTKEQLVYI--LPL
ER--TNKFPDFFRDLDKYSGQ---------GLMNY--EVSMS----TLNEVFMNLEGE-S
TTKQN----------------FE-KRETR--------RDSESLNEME----PACPSLS--
----EVQKT-V-----------------------SVMSRWRMQVCAIARL---------R
ILKLKRE-RKAFLTFLLILGIALFPLIMEKMAYAVIVQ-KTNWEFKPELYFLSPGQLP--
QGLRTSLLII-----NN--TES-NIEDFIQSLKHQNIVLEVDDFE----NRNG-TESLSY
N-GAIIVSGRQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLHMFN----------
----------HSQY--IRIEE-----DLV-------------IFWFGIMDGSLFLLFVVC
SISPHIAMSSASDYKRKA-DSQLWISG-LYPSAYWCGQ-AVVDVNIF-------------
---GIILLSVYF---TLYMIHM---MHI---YLTSEVVLCIVVLAFGCAASLVFLTYVIS
FVFGKRRKNSGLWSIGFFVV-----VIIIFDML-LN--FGFSE-TLLITLMTIVPSF---
--SLT--------TFLIVLEMRA----------HQHYAEFGE---IKYGLSGADYLLCLI
PYFHALLFIFILRCLE-LKCGKNVIQKDPIF-RISPQSLNGQLNPEERRGED--EDEDVQ
AERIRTSAALS-TSNSN--ERPVIIANGLHKEYAGQKKNCFSKRT--KKVAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPNGAGKSSSIRMIAGITKPAAGEVE-LK--GFSSA-VGFHGDG-----TIK
FGYCPQENVLWPILTVKEHLELYAAVKGLRKEDAV-----IAISR----LVNAFKLHDQL
NVLVQKLSAGDT---RKLCFVLSILGNSSVLILDEPSTG----LDVSG-KQQMWQAIQAA
VKDNEKGVLLTTHDLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKKK-FGMDYILELKVNETSQVPLV
HGEILKLFPQAA--HQERYLSL--LTYKLPITDVYPLSQAFHKLEAVKHSFNLE---EYS
L-SQCTLDKV----------------------------------------------FLEL
SKEQELGSVH-EEAAA-TMRWKLLPHLEEL---------------------
ENSFCAP00000027595 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKKKISVYQQTQALLYKNFLKKWR-----MKK
ESLSEWT
PF12698 // ENSGT00760000118965_1_Domain_0 (548, 1542)
IT-LLLGLYFC--IFS---GLFRATHLPEQPPH--VLGRVDE--FNDSDLV-V
AYTPVTN------MTQKIIDKMSSASFM------------------------------KG
VL--P----N----VSLLCNL-----HHEMVGIVFNDTF-SY----QLKAKVKGLNPHGL
MALHNDGMFLSFLQE----------------HCWDM---HDDI-FC-------YVTRY--
WQNGFVAFQTAINAAIIELTTNHSVMETLTSVTGINMRMPSF---------VSKGEVI--
NTWFIFICIVYFSPFVYSTSLNV-----------TKERKKCKKLMAVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFVFILSIAMAL----------IITLSKTVVIVGFLVIVTLFVLYG
LSLIALAFLLSV----------------------------LIKKPVLT---SLVG-----
FL-FTTFWGC--------LGFTVLYRQLPSSLGWILSLFSPFAFTAGMAQISRMDYY---
------LMGVTFPDPSGESHVMMVTFSILALDALLYLILML
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFERALPDE---GGHPCSP
LFFLKSSFWSQHR-NTHHEV--FEDEINPEHY-PDDSFEPVPLEFHGKEAIRIRNIRKEY
-------------DGK------P-----------------------------ENVEAL--
--Q-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1839)
-GIFLDIYEGQVTAILGHNGAGKSTLLNILSGLSVPTK--GSATIYNTQLSEITNM
EETRM-NIGFCPQF--NIQFDFLTVRE-NLRLFAKIKGIQSKEVE-QEVKRVIMELDIQN
TQDVIAKKLTGGQKR-KLTLGIALLGDPQV--LLLDEPTTGLDPFSKHQVWNLLKER---
---------------KTNRVILFSTQIMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---QKWGI---GYHL--RQNLK-Q----------------------A
-----------------------------------PGSEL--------------------
SA--QSPARDLYRDLEKCSNQ---------GIMNY--DVSMT----TLNEVFLNLEGK-S
TIDEP-----------GII-MRE-KVNET--------RDAGTESEMQ----QAPCSLP--
----GLRKA-I-----------------------STRTLWRRQVCAMARL---------R
FLKLRHE-RKLLLSLLLLLGIPLIPTIFVKIAVALSHS-THCRELSSSMYFLSLEQPS--
QTPLTSLLVI-----NN--TGS-NIEDFMQALKRQDILLEVDDFR----NRNG-SDDPSY
N-GAIIVSGDR-KDYR---FSVACNTKRMTCFP-VL-MGIVSNALLGIFN----------
----------FTEL--IKTERSTFPFNGV-------------LVEFGFVNGPLFLLVLAN
CLSPYIGMSSLSDRKVRG-GSQLWISG-LCPSAYWIGQ-ALVDIPLY-------------
---CSILLSPYD---LMISL----------------------FPIPYATSSLIFFTYVIS
FIFCKRRKNNGLWCLGFLIV-----SIYAYIFL-DL--FGFSP-----------------
-------------------------------------------------LIHPNIKVGLS
PYLQSIIFLFVIRCLE-MKYGQKTMRKDPVF------SRENHPNPEEPEE----EDENVQ
AERARTANALT-TLNPD--EKPLVVASCLHKEYKEKKEHCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEVLGLLGHNGAGKSTSIKMVTGDTKPTAGTVR-Y-----RT-SPRQPEDD----TVKF
LGYCPQENSLWPGLTGKDHLELYAAVKGMSKQEAA-----LSTSR----LVEAFKLQEQL
KVPVKDLAQEVK---RKLCFALSVLGDPSVVLLDEPSTG----VDPEG-QQQMWQAIQTI
VKNTEKGVLLTTHSMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQNLKSK-FGKDYVLEVKIKDPTQVEPV
HTEILKLFPQAA--RQERYSSM--MAYKLPVEAVRPLSQAFFKLEAVKQTFDLE---EYS
L-SQATLEQV----------------------------------------------FLEL
SKEQELGNLD-DEVDT-TVRWKLLPQEEP----------------------
ENSCATP00000017956 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MKYEIEIMNKDPVF-RVSPRRRETHPYPEEPEE------EDVQ
AERVQAANALT-TPNLE--EEPVITASCLHKEYYEAKKSCFSTRK--KKIAIRNVSFC--
--
PF00005 // ENSGT00760000118965_1_Domain_5 (2883, 3064)
EVLGLVGHSGSGKSTSIKMTTGFTKPTAEAVV-LQ--GNRA-SVKQQRDN----SLKF
LGYSPQENSLWPKLTMKEHLELYAAVKGLGKEYA--------------------------
---------------RKLCFVLSILGNPSVVLLDELFTR----MYPEG-QQQMWQILQAT
VKNKERGALLTHP-----------------------------------------------
---------------------------------LHIFTR-N-------KKMKEPTQVEAL
HTEILKLFPQAA--QQERRSSL--MACKLPVEDVHPLSQAFFKVEAVKQTFNVE---EYS
L-SQGTLEQV----------------------------------------------FLEL
RTEQALGNVD-DRSTA-V---------------------------------
ENSTBEP00000004370 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----EWLLS-FLPLLLAY--LL-S--SNLHQVNDSQIPAV--NLGRVDT--FNDS-DYII
AFTPESK------TTHEIMNKAASAPFM------------------------------QX
XX--XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX-XX----XXXXXXXXXXXXX-
---XX----XXXXXX----------------HCHA---TNE-KVRC-------KSSMF--
WEEGFVAFQAAINAAIIEITTNHSVMEELMSVAGINMKILPF---------IAQGGLA--
TDIFIFFCIISFSALIYNVSVNV-----------AQERQYIKSLLIMMGLREAA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGVLY-AGFIFIIATLMAF----------IIKLTQVVVLTGYVVVFTLFLLYG
LSLITLGFLMGV----------------------------LIKKPFLT---GLVV-----
FL-FIVFWGS--------LGFTALYAHLPAFLEWTLCLLSPFAFSVGMAQLIHLDYD---
------INSDVPLESASNPYLIMATLFMLFFDTLLYLVLTLYFDKILPTE---YGHRRSP
LFFLKSSFWFRHQRA-NHVA--LENETDSDSS-SNDCFEPVSPEFHGKEAIRIKNLKKEY
-------------AGK------H-----------------------------EKVEAL--
--R--GVMLDIYD
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
-QITALVGHSGAGKTPLLNTLSGLLVA-S--GSVTIYNHTVLEIADL
ETVSK-LTGVCPQS--NVHFGFLTMRE-NLRLFAAIKGISPHEVE-QEVLRVLRNLEMEK
SQDILAENLSGGQKR-KLTFGMALLGDPQV--LLLDEPTAGLDPLSRHRVWTLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPKNI-TSLVKQH--------------------IPDAKL----TAQSEEKLVYL--LPL
ER--TNKFPELYRDLDRCANQ---------GIENY--GVSMT----TLNEVFLKLEGK-P
TIDESDIG---------LW-GQL-QSDGE--------KDMGSLAELE----QVLSSFE--
----ET-RTIV-----------------------SGMALWRQQLCAIAKV---------R
FLKLKNE-RKILLVXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX--
XXXXXXXXXX-----XX--XXX-XXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXX---------
-----------XXX--XXXXQDTSFK-------------------NEHPVDANLWV-PAA
CFSPYIAMSSIGDYKK-KARSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLIQI---LDYIFSPADI------ILIIKGLLIQILCTVGYVSSLIFLTYVIS
FIFHS-RGKYDMWSFFFLII-----TIFSVVVTEI---NVYAF-KELLFIALLMPPF---
--TLM--------GCLLILNEF------------SD--TDS-EA----SGSQAVFLASLI
PYFHFFIFLFVLRCLE-ANFRKKSMRKDPVF-RISPRSCDVFPNPEGPE----GEDEDVQ
MERMKTANAVA-IPVTD--EXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVI-LK--GSS-------GGD----TLGF
PF00005 // ENSGT00760000118965_1_Domain_5 (2941, 3053)

LGYCPQENALWPALTVKEHLEAYAAVKGLKKEDAK-----VAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKVCFVLSILGNPSVVLLDEPTTG----MDPEG-QQQVXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------
---------------------------XXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX--XXXXXXSS--MVYKP--DDVR--LSQAFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SREQELEGFD-EELDP-SVKWKLLPQEEP----------------------
ENSSSCP00000054954 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMAMASFM------------------------------TG
RT--IIGTPDEDTMDRVFPKN-----DSEMVGIVFTDTF-LY----RLKFPWGHRTPDI-
---GE----HFEYSG----------------NHGRM---D----------------SS--
ILRGFVAFPTAMNAAIIEVTTNHS
PF12698 // ENSGT00760000118965_1_Domain_0 (805, 1542)
VMEE--------------------------------
----------------------L-----------TSERKKCKKLMTLMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWALMD-AG-FIIII---SAFMA---LVITLVQ---IIVITGFMVIVALFILYG
LSVIALA--------------------FL--L-NVLV-R-KL-IP-A----GL-VG-FL-
FT--VF-W-GC-------LEFTALYTQLPSPLKWAFGPFSPFAFTAGMAQILHRAYY---
------VNGVVFPDPSGESYMMIMTFFILAFDTFLYLMLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1692)
YFERVLPDE---DSHRLPL
LFFLKSSLWSPNQNT-HREV--FENEMNPEHS-SGDAFEPVSPELHGKEAVRIRNVKKEY
-------------NEK------P-----------------------------ERVKAL--
--Q--GAGLTV
PF00005 // ENSGT00760000118965_1_Domain_3 (1692, 1840)
CEH--------------------------------IILQNKLLSEIMST
EEIRK-NTGFCPQF--NIQFDFLTVRE-NLRLFAKIKGIQPKEVE-QEVKRVIMELDIQN
FQDVVAERLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHRVWNFLKER---
---------------KTDHVILFCTQFMDEAD----------------------------
--------------------L---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CGTEGT-TSLVRRH--------------------VSD-----------------------
-----------------------------A---K----L-------T----A---E----
S----E---D--------K------L---V---Y---G----L---P-------L-----
----E-----------------------------R---T---D-----K-----------
--F---P----G---L---C----R---D---L---------------------E-----
-E---S---------------S----D-----------------------------Q---
--G---I---M---N----F----D---V---S----M----T---T-------------
---------------------------------------------------------LSE
VFLNLKGESAV------------DEPG-I-TMCVWQKI-KEKKMITY-------------
---PFIFVDLY-------------------------------------------------
-----------------------------------------------------VEF----
-------------------------------------------------------YLEWN
SFFFFFFFLFVIRCLE-MKYGRETMRKDPVF-RISPRRRENHPNPEEPE----DEDEDVQ
VERTRTASALT-PSNLD--EKPVIMASCLHKEYKEKK-------K--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
QNVSFCVN
KGGVLGLLGHHGAGKSISIKMVTGDTKPAAGVVV-LH--GSGTALK-QQEGG----VMGF
LGYCPQENSLWPDLTMREHLELYAAVKGLGTEDAA-----LSVSR----LVDALKLQDQL
KLPTKASSEGIK---RKLCFALSILGNPSLVLLDEPSTG----MDPEG-QQQVWQAIQAA
VKYTERGALLTTHYMAEAEAVCDHVAIVASGRL---------------------------
---------------------------RWVPVQSQYLSPTFLDRELL--EGEGTHSGEPL
HTEILKLFPQAPLM--------------------------SVPLSAVKQTFDLE---EYS
L-SQATLEQV----------------------------------------------FLEL
PKEQEWGNFD-DEVDT-TVRWKLLPQEEP----------------------
ENSXETP00000047612 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FRLSWGLLY-AGYILIVANLMTL-----------ITKPFIFMTSSYGVIMFLFFLYG
VALMSFTFMLSA----------------------------LFRSPRAT---AVAG-----
FF-ITLFLSA--------LGLVLLRKDIPQAFAVLLSIFPQFAFAVGLLQVI--LSD---
------LEGVYFSDLMGDSSHMLSCFISLVLDSVFYMILTLYFEKVLADK---HGVKHEP
LFFLKASYWSKEKPS-PLM---AQTDYSGESS-LGDFVEKVPDDLHGKEAIRITNLLKSN
-------------LKK------N-----------------------------WRVSAT--
--K--SLDLNIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNILSGMYPASG--GSATICNYKLSNMRHL
EEIKK-RVGFCPQG--DIKFDPLTVKE-NLMVFAMIKGIPTKQVA-HKVQKVLSDLQMND
IAYTEVITLSGGQTKQTLLWSVEILYYVQV--LLLDEPTAGLDPCSRHHVWTILKEN---
---------------KADRVTLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAVISKGR
LKCVGS--SLFLK---RKWGI---GYHL--RMQVS-P----------------------S
CDVELM-TSIIKQR--------------------IPSAKL----TAQNEEELTYA--LPF
EN--MDVFPDLFSHLDGQVGN---------SIVSY--GVSMT----TLDDVFLKLEGE-G
EIESGDYD---------VF-NPE-SRTAE--------DREDISAEME----ESLLLMS--
----DSGNVTL-----------------------SGWELWRQQVLAVARI---------R
FLKLRHD-TKSLRSILLLLVLFILVPILSIIMAHISNK-FISWELTPSLYFQSPGSRL-N
-KYYTDLLIH-----NN--TGS-SIDDFIGAVKEQNIAVQVANGK----Y---DMDTIKY
R-GAIEVSQAE-KCRN---ICLPQYLYLY---T-LS-ISICQTGFLFLFQS---------
-------ML-DSRH--VK-RVRLAFQDE----------MDIHHKTYISIM---FFMIFAS
GLSPHIAISSTEDNRI-NARTQLRLAG-LFPSAYWFGQ-ALVDVILY-------------
---WSLLFLMTA---ILFAFNNYSY----FLLNFITAMVMIAGMF-GYGMAVILYVYVIS
FIFGKGKIHRDSWSLFFVIL-----YSSLALLCQ------GQT-L---------------
VISVF--------KFVQPSHFKSLGSCRYRVLVEFV--NLKFGPILNRPQKKNLFLLILQ
PYLHIIIFFGLLWFLE-WKFGLRSLTTDPLF-RISRRNMTVKKNPEELG---NDVDEDVL
AEKERVKNAAT-VANVE--EKPVIIVDSLRKEYKVKKRGSFFKKN--RKAATKNISFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGPNGAGKTTSMYMLAGEVKPTAGEVV-LC--GNDPAE-----------STGF
LGYCPQDNPLWPNLTVKEHLEIYAAVKGMKKEDAY-----IAINR----VAAALELKEHM
GKESRKLSLGES---RKVCFAISMIGNPNIVLLDEPSTG----LDPKA-QQRLWRAIRAA
FKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQQLKSK-FGKGYLLEIKVKETHQVDQI
HNEIIRIFPHAA--RQDRFSSL--LVYKIPMDNVQSLSQAFLLLEEAKRAYNIE---EYS
F-SQSTLEQV----------------------------------------------FIEL
AKEQEKEDFE-L--NN-TFQWRHLRAESI----------------------
ENSCAPP00000009525 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRHISVGQQMWTLLLKNCLKKWR-----MKK
ETLLEWFFS-FLPVLFAF--LFSS--NLHQVSDYSQMPAM--DLGRADN--FNDT-NYII
AFKSYLT------I---------FFLHM------------------------------AG
RT--IMGWPDEKSMTELDLNY-----SIDAVRVIFNDMF-SY----HLKFSWGRRIPEI-
---KE----HKDHSA----------------V-------DE-QITC-------ESSVF--
WERGFVAFQAAINAAIIELAVNHSVMEALMSVTGVNMKIPPF---------IAQGGIA--
TDFFIFFCIISFSSLIYHLSVSV-----------SKERKYLKSLMTMMGLRES-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---ITLAFLMSV----------------------------LIKKPYLT---GLAI-----
FL-LIIFWGS--------LGFTALYRHLPATVEWTLCLLSPFAFTTGMAQLIHLDYD---
------VNSNAHLDASNNSYIIIATLFMLVFDTFLYLLLTLYFDRIFPKA---YDHQERA
Q--QKSSFYKSGRNV--------------------DSQFPQML----SFFCRIKNLKKEY
-------------KGQ------R-----------------------------EKVEAL--
--K--GNKHI-YL---IWLFGWH------CV
PF00005 // ENSGT00760000118965_1_Domain_3 (1712, 1840)
ALMATLYFAIT--GSVTIYGHKLSEMADF
ETLSK-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILSHEVE-QKVQQILRDLEMEN
IQDFLAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2450)
AGLDPLSKHHIWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LAGKF----CGT
LAFARN--SLYKN---DE-------IIQ--HLHLN-E----------------------M
CDPESV-TSLVKEH--------------------IPDAKL----TEQSEEKLVYV--LPL
ER--TNKFPGN-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--NLRNE-RKSLLAMLLLLGVGFVPQLLEFLFYEIYQK-SYSWGLSPDMYFLSPGQAA--
AGPLTHLLVI-----NK--TGA-SIENFLHSLRRQNIALEVDAFG----TRNG-TEELSY
N-GAITVSGDKQ-DPR---FSIACNTKRLNCFP-VL-IDIISNGLLGIF
PF12698 // ENSGT00760000118965_1_Domain_4 (2450, 2769)
NS---------
-----------TEH--IQTGRSTFFEEH-------------ASYNYGSLGSAFFWIPLAG
CFTPYIAMSSIDDTKK-KVHSQLWISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLIQI---MDYVFSPEEI------IFIIQNLLIQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLTV-----TIFTIVAADV---SEYTF-LGILFCTILVPPF---
--TLI--------GSLSIFSEI------------SYDSVDYLGA----SESQIVFLALLI
PYLQFFIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2881)
LFVLRCLE-GHFRKKLLRKDPVF-RISPRSSDVFPNPEEPE----GEDEDVR
MERIRTTNAVT-SLDEE--EVKAT-------------KRFFV---------KPFYLILFL
PF00005 // ENSGT00760000118965_1_Domain_5 (2881, 3037)

SGEVVGLLGHNGAGXXTVIKMITGDIKPNAGQVI-LK--RNS-------EGD----DLGF
LGYCPQEDVLWPNLTVKQHLEVFMSVKGLKKRDAM-----VTTAQ----LVEALKLQDHL
KTPVKTLSEGIK---RKLCFALSILGSPSVVLLDEPSTG----MDPEG-QQQIWQAIRAT
FRHMDRGALLTTHYMAEAEAVCDRLAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVRSLAQVQPL
HAEILRLFPQAA--RQE-------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSGALP00000033886 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MESPLPA------GKM----QRVFKKASKINQQTWTLLWKNILLVWR-----KKT
ESFQEWITI-AILLLLIQ--ISS---ITIYHYEWQEIPYK--FLGRLDDPAFSVR-GVKL
IYTPATS------TTRRIMGRVASGSVL------------------------------KG
IA--LEEAVNEQNLSARGLFR------SDVIGVVFKDDF-SY----HLRFQSYSVIS-P-
---IE----TFEHID----------------TCYD----FS-SSFC-------KVPLY--
WYEGFLSVQSSIDAAVIEMKMNHSVWEEMKSISGIRLQS
PF12698 // ENSGT00760000118965_1_Domain_0 (820, 1542)
PLI---------KSIRKVG--
YIWFTIYSMLCFSPYMYFLSVKV-----------IREKKKLKVLMKAMGLQDIA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-TIYISITSSLLTA-----------ITIRSVTHNCSFSEIYFLYFFYG
IASIHFCFMLSS----------------------------LLKQPHIT---SFVG-----
FF-LHVVFGS--------LGFMTFFEEVPPSLEWVFNLFSPYTFTAGISKIVKLEKY---
------GPTV-----AAELYPFFNLYGMLILDSILYLLLAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKVLPGK---YGVPYPP
LFFLRPSYWLQWGSK-R------STQPDPIPV-PGCDTEPMPEGFEGKEAIRLYNIRKTY
-------------KRK------G-----------------------------KITEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-R--GLSFNIYEGQITALLGLSGSGKTALLNVLSGFSKPSA--GSAVIYNYKVSEVQDM
EGIQA-MVGICPQL--NLHFEALTVKE-NLRIFAHVKGIQWKEVE-QEVQKVLVQLDLTD
LQDVHADSLSGGQKR-KLSLAIAILGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2471)
MVGLDPCSRHHVWELLAER---
---------------RAGRVTLICTQSVEEAD----------------------------
--------------------A---------------------------CADRKAFLSNGR
VQCVGS--SLYLK---RKWGI---GYHL--RICIN-D----------------------Q
CDPGLA-SSLVRRY--------------------IPNAVI----KGQDGDELCYV--LPL
EN--TKSFPDLLGHLDSGLVL---------GVVHY--EVSRT----TLADALLQLEGR-E
AIDHKGA---------------------------------ENLKESD----QSFLGFS--
----EPAHIAA-----------------------SGMELWRQQVLAVARV---------R
FYRLRHD-GKLLRSVLLFFGVFIIQMLMVFFGFELWNK-SIS-ELTASKYFLPAQPPTQT
QSKSTNLLIF-----ND--TGS-EIEDFIAALKIQNIMPEITLEK----N---ITSLPRH
N-GAIKISLEG-KHRR---YTLMCGAEPINCFP-VL-INTLSNTFLRLFS----------
----------
PF12698 // ENSGT00760000118965_1_Domain_4 (2471, 2771)
STAR--IRIWSHPFSRA-----------EDPELGRGIFFFCLTYMLILAA
GLPPQFAVSSVEDYKI-KAHAQLRVSG-LFPSAYWCGQ-ALVDVPLF-------------
---WALMCLMFVVV---LLFNRI-------CPMQAFIILPLIFSAIGYGFSLIFLVYLIA
FIFRKGRTNRYLCSFVFVLV-----NFTLRMFS-------FRQ-GFFYIFSTLMPPY---
--PLL--------GWLTFSTA-----------HLTFFSNGNLLHDTWSNILVAVF----A
PYIHSVLFGF
ENSGT00760000118965_1_Linker_4_5 (2771, 2872)
LLCCLE-IRYGEAVAERDPIF-RIQRRRALPPQNNHPPG----QEPPEVQ
AERERARSAVS-SQ-QP--KESVIAVNGLRKEYEDKRACSIFKKK--KKVA
PF00005 // ENSGT00760000118965_1_Domain_5 (2872, 3038)
VKNLSFCVK
KGEVLGLLGPNGAGKSTTIRMVSGDIAVTAGEVL-LQ--GCRAA---------------V
PGCCPQENPLWSDLTVLQHLEAYAAVRGVRGEDAA-----VFISR----VAKALDLQKCL
KTPARRLSAGEA---RKLCFALSILGNPTVMLWDEPTAG----MDVAG-QRCLWKAIQAA
VRSKERAAVLSTHCLEE-AAMCDRVAVLVAGQL---------------------------
---------------------------RYIGSPEELRRK-SGMSYHLEVKPKDVGQSDAL
HSEILHLFPGAA--RQKRISSL--LTYKIPMEDALPLSQAFSKLEAAKQNFRLE---EYS
L-SLHTLQQV----------------------------------------------FMDF
SGDLEEPDLE-ATNEG-AAEQTLLQP-------------------------
ENSPCAP00000005675 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRQISLCQQTGALLCKNVLKKWR-----MKR
ESLMXXXXX-XXXXXXXX--XX-X--XXXXXXXXXXXXXX--XXXXXXX--XXXX-XXXX
XXXXXXX------XXXXXXXXXXXXXXX------------------------------XX
RP--VMGLWDEESIYELSENY-----PEEIVQVIFTNTF-SY----HLKFFLRQRIPTR-
---VE----HHDHTA----------------HCYEL---DG-DIYC-------GVSKI--
WKKGFVAFQAVINAAIIESTTNHSVMGELMSATGKIMKLNPF---------ISQDGPM--
TDIFVFFCIIAFSPLTYYASVSV-----------TRERKKMKGLMTVMGLCDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFIMAFFVAL----------IIKSSQFVILTGFVVVFTLFLLYG
LSLIALAFLMSV----------------------------LVKKSFLT---GLVM-----
FL-LTVVWGS--------LGFTVLYRHLPSSLEWTLSIFSPFAFMLGMTQXXXXXXX---
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLMVYFEKVLSNE---YGHRHSL
LFFLKSSFWSRQQKA-DATA--LEEELDSDPS-SNDSFEPVSTEFHGKEAIXXXXXXXXX
-------------XXX------X-----------------------------XXXXXX--
--X--XLTFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK---SVAIYNNKLLETTDF
KNVSM-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIRGILPQEVD-KE------------
-----------------------------I--FLLDEPTAGLDPFSRHCMWNLLKER---
---------------RKGRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRRVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQVN-K----------------------M
CVQEKI-TSLIKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TNKFPELYRDLDVCPGL---------GIENY--GVSMT----TLNEVFLRLEGK-S
AVEESDIG---------IL-GEV-QAEGA--------GDIESLDKIE----QVFSLLN--
----EV-KNTI-----------------------AGMALWGKQVWEIAKV---------R
LLKLKHE-RRPLLSLXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX--
XXXXXXXXXX-----XX--XXX-XXXXXXXXXXXXXXXXXXXXXX----XXNG-TDDPSY
N-GAIIVAGNK-KKYNFS-L--VCNAKRLNCFP-VL-MDIVSNGLLGMFKP---------
-----------SAR--IRTDRSTFWEVE---------------WPLGFLPFTVFWLILAA
NCSPFIAMSSIEDYKN-KVRSQLRISG-LFPSAYWFGQ-ALVDIPLY-------------
---CFICLFIYM---MEYVVSTEEI------LFKLVNKIIQILCTLGYAASLIFLTYVIS
FISRNGRKNSGMWAFCFHII-----TMFSLVGLVF---ANEGS-SALLCITFLVPPA---
--TLA--------GCTLLSLRX------------XXXXXXX-XX----XXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXQCQPEDPE----GEDEDVQ
MERVKTANALN-STNFD--EKPVIIANCLRKEYTGKRKGCISKRK--KKIATRNVSFCVR
KGEVLGLLGHNGAGKSTCIKIITGDTRPTAGQXX-XX--XXX-------XXX----XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX----XXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-XXXXXQAIRAT
IRNTERGALLITHYMAEAEAVCDRVAITVSGRL---------------------------
---------------------------RCIGSVQHLKSK-FGKDYLLEMKVKIPAQVEPL
HTEILRLFPQAA--RQEXXXXX--XXXXXXXXXXXXXXXXXXXXXXXKQSFDVE---EYS
L-SQCTLEQV----------------------------------------------FLEL
SKEQELDDFD-EEIDP-SVKWKLLPQEEL----------------------
ENSMOCP00000016204 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRVGQQTWALLCKNWLKKGR-----MRR
ETAMEWF
PF12698 // ENSGT00760000118965_1_Domain_0 (548, 1542)
FS-FLLIFLTY-QLSS---DLHQVHDAPQIAEM--DLGRVDD--FNDS-SYMI
AFAPETK------TVYEIMNKVASAPFM------------------------------KG
RR--IVACPDETCMSELDLNY-----STDAVRVIFKDTF-SY----HLKFSWGQRIPQI-
---KE----HRDHSA----------------PCETM---G-DKITC-------RNSIF--
WERGFVAFQAAINAGIIEMATNHSVMEELMSLIGSHMKILPF---------ISQGGVA--
TDFLIFFCVISFSSFIYYLSINI-----------TQERQYITTLMATMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AVFILVMATLMSL----------IVKSAQIVVLTGFMVVFLLFLLYG
LSLITLAFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTIFWGS--------LGFTALYRHLPAFMEWSLCLLSPFAFTAGMAQLIHLDYD---
------VNSNANLDSPNNSYLIIANLFMLILDAFLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLSK---YGHRRSP
LFFLKSSYWFQHRRA-NNVV--LENETDSDPP-LNDSFEPVPPEFQGKEAIRIRNLRKEY
------------T-GK------H-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLGFDIYEGQITALLGHSGAGKTTLINTLCGLSPPTT--GSVTIYNQTLSEMDDF
DAVVK-LTGVCPQS--NIQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQRVLRDLEMEN
TQDILAQSLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPLSRHRIWNLLKER---
---------------KVDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------I
CDPESV-TSLVKKH--------------------IPDARV----TTQSEERLVFI--LPL
ER--TNKFPDLYRELDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
VTDES---------DIGSS-GHL-ESEGA--------EAMGSLAELE----QMVSSRD--
----SSGDM-K-----------------------SGMALWRQQLCAVAKV---------R
FLKLKRE-RKSLMTVLLLFGISFLPQVLGYLIYELQHE-NYSWGLSPSMYFLAPGQPP--
QDPLTHLLVI-----NK--TGS-SIDNFVHSLRQQSIAVDIDVLG----TGNG-TEEVLY
N-GAITVSGDE-KDLR---FSIACNTKRLNCFP-VL-VDIISNGLLGIFN----------
----------SSER--IQTDRSTFVEEHMI-------Y-EHEHL-----NSAFFWIPLAA
SLTPYIAMSSISDYKRKV-LSQLWISG-LYPSAYWCGQ-ALVDIPLY-------------
---FSILFLMQI---MEHVFSQEEI-----MFIIENLL-IQTLCSIGYASSLIFLTYIIS
FVFRNGRKNSGVWSFFFLVV-----TSFSLIANEI---NVYGF-LGLLFSTLLIPPF---
--TLI--------GSLFIFSEIS----------YDS------MDYLGASESQVMFLALFI
PYFHFLLFFFVLRCLE-RYSRKKLLRMDPVF-RISPRSCHAFPNPEEPGE----EDEDVQ
MERTRTADAVT-ALQMN--EKPVIIASCLRKEYAGKKKKCFSKTK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTKPTAGQVF-LK--GCSE-------GT----TLGF
LGYCPQENLLWPVLTVKEHLEVFAAVKGLKKKDAT-----VAITR----LANALKLQDQL
KAPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLTQVESL
NTEIMTLFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFHLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDLD-EELDS-SVKWKLLPQEEP----------------------
ENSMICP00000015725 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSTKQRSVYQQTQALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCLG--LFS---NFVRSDQFPETPPH--DLGRVDQ--FNSSFRM-V
VYTPISN------VTQQIMNKTAFGLLL------------------------------KG
ER--VIGVPNEEHMDKMLSEN-----LAYAVGIIFNDAF-SY----KLKFFQGYEIPAL-
---SD-----EDLSA----------------HCWEG---YE-DFHC-------FLTTY--
WNRGFVTLQTAINAAIIEITTNHSVMEDLMSVTATNMKTLPF---------ISKNGLQ--
SEIFILYCSLYFSPLIYFMSLNV-----------TKERKKCKDLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLFY-AVSNFIFSILITI----------VITSTQIIVMTGFMVIFTLFFLYG
LSLIALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVLYKQLPSSLEWILSICSPFAFTAGMIQIIRMDYN---
------LNGVIFPDPSGDSYVMIATFSILALDGLIYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---SECRYSP
LFFLNSSSCFQHQ-RTDNKV--IEKEIDPEHP-SDDNFEPVAPEFQGKEAIRIRNVKKEY
-------------KGR------P-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1830)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLCEMQDL
EEIRK-ITGICPQL--NIQFDMLTVKE-NLNLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQNNLAGHLSEGQKR-KLTFGIAILGDPQ
ENSGT00760000118965_1_Linker_3_4 (1830, 2372)
V--RHLSF-----------------------
------------------------------GI----------------------------
--------------------L---------------------------SFDRKVIMSNGK
LKCAGS--SIFLK---RKWGL---GYNL--SLHRN-E----------------------T
CDPEQI-TSFINHH--------------------IPGAKL----KTQNEENLVYT--LPL
ER--TSKFPDLFSALDKYSAQ---------GVMGY--DVSMS----TLNEVFMKLEGK-S
SIEQD----------------FE-QVEMT--------GDSASLNEME----PAHSSLS--
----EMLKT-V-----------------------SGMGLWRMQVFAIARL---------R
FLKLKRG-RKVFLALLLVLGIALSPMIMDNVLHAMFNQ-KIDWEFKTGLYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIQS
PF12698 // ENSGT00760000118965_1_Domain_4 (2372, 2717)
LKHQSILLEVDDFK----NRNG-TDGLSY
N-GAIIVSGKQ-KNYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQY--IRIERSPHPLSSV-------------SLWAGLPEASTFLYFILC
STSPYIAMSSISDYKKKA-KSQLWISG-LYTSAYWCGQ-ALVDINFF-------------
---TLILLLMYF---IIYIHNM---ANI---YTTGRIVLALVIITPGFAASLVFFTYVIS
FIFRKRRKNSGLWSFCFYFV-----STIMLIII-II--NHFAL-IIIITSMLLVPSF---
--TLF--------GFI
ENSGT00760000118965_1_Linker_4_5 (2717, 2873)
TFIEEV-----------RNHYRKFEE---LNFDLSEADLLVCLI
PYFQALLFIFVLRCME-LKYGKKRMQKDPVF-RISPQSREARPNPEGPTD----EDEDVQ
AERIRTATALT-TSNLD--EKPIIIASCLHKEYAGQKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSD-SR--------GTSKF
LGYCPQENVLWPVLTMREHLEVYAAVKGLRKGDAK-----VVITR----LLDAFKLHEHL
NVPVQKLTVGTT---RKLSFVLSILGNSPILLLDEPSTG----MDPIG-QHQMWQAIQAA
IKNRERGVLLTTHDLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYTLELKVKESSQVTLV
HTEILKLFPQAA--QQERCPSL--LTYKLPLADVYPLSQAFHKLETVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEEGDFD-EEVDT-TMRWKLLSHSDEP---------------------
ENSFALP00000002626 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------M------------------------------AG
II--IEEMENEAKMEEKGILE-----EEETIGVVFKDDF-SY----ILRFQVGRAVF-P-
---NE----GFEHIE----------------TCWD----FS-SRHC-------KVPLY--
WYGGFLSVQSSIDAAIIEMKTKHSVWKEMKSITGVQLRSV-L---------KPLFKLD--
YLWFVICAILSYCPYMHFLSLKV-----------LKEKKKLKVLMRAMGLQDLA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-TVYISITASLLTW-----------ITLSEVLNHNSFLELYFFYFFNG
MASIHFTFLLSS----------------------------LLKQPNIS---SFVG-----
FL-LHILFGA--------LGFLTLFEKLPRALEWTLNLFSPFAFTAGLSTMVKLEKY---
------GPAA-----TPELYPFYNLYLILSFDGVLYFLLAIYFDKVLPAK---YGVPHPP
AFFLRGWYWLRGSRG-CVE---VRAGSGHDPV-LGCDTEPLPPGFDGKEAIRLNNIKKIY
-------------KKN------N-----------------------------QSTEAL--
--K--GLSLNIYEGQITALLGHSGSGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TALLNVLSGFSKPSA--GSAMIYNYNASEMWNV
EGMKE-KVGICPQV--NLHFEALTVKE-NLRIFAHIKGIQWKEVD-EEVQKVLVMMDLTD
AQDVCADALSGGQKR-KLSLGIAILGNPQV--LLLDEPTAGLDPCSRHHVWSLLRER---
---------------RAGRVTLFATQSMEEAD----------------------------
--------------------A---------------------------QADRKAFLSCGR
LQTVGS--SLYLK---RKWGI---GYHL--RMHIN-D----------------------R
CDPELV-SSMIRQH--------------------IPDAVL----KGQKRDELCFG--LPL
EN--TDSFPDLFSHLESSPLQ---------GVVNY--EVTRT----TLEDVFLKLQGE-E
AIDPQGD---------------------------------ADLEERE----QNLAGLS--
----KQGILAM-----------------------GGMMLWRQQVCAVLRI---------R
LLRLKHE-GKFLRGVLLLFGAFILPPLMVLMLFHLWHN-SSSWEITSSPYFIPMKEK--I
QNRSTNLLIL-----ND--TGS-EIEDFIAALKSQNIIPELTLEE----N---ITSLPNY
N-GAIKISLEG-KSRQ---FTVMCSPEPINCFP-AL-LNILSNTFLRLLD----------
----------SPAR--LRLWSQLFYTA-----------ENAELKHYIFYGLFTYLLVLAA
GLPPFFAMGSVEDYKL-QARSQLRLAG-LFPSAYWCGQ-ALVDIPLF-------------
---WSLLCLMFGLL---VLFTRV-------CPLEAHAVLSLLICIFGYGISLVLFVYLMA
FKFRTGRSNRYIWSLTFILV-----NYAAFMNG-------DHN-QVLYYICMLIPVF---
--PPV--------GWIMFSGL-----------NFLLY-NDHMIFARWNYIYLPTL----A
PYVHGVIFAFLLRCLE-MRYGEAVPGFDPIF-RIQQRGRVPQQNKELPA----EEPPEVQ
AERDRVRSAVT-SL-QQ--DQDLVIVNGLRKEYEVRTATSIFKKK--KKLAVRNLSFGVK
KGEVLGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTLKMISGGVAVTAGEVL-LR--GGDGAHL----------CPGA
LGWCPQQDPLWPHLTVLQHLEALAAIRGMGEEDAA-----HAISC----IGRALDLLKHF
KTQVRSLSAGEA---RKLSFAVSILGEPAVMLWDEPSVS----VDPKG-QRCMWKVIQAS
LRSRERAAVLCTQSLEEAAAMCDRVAVLVSGRL---------------------------
---------------------------RYIGSIEDLKSK-FGTSYHLQLKMAEVGQSDSV
HTEILKLFPHAA--RQERTSSL--LTYKIPVADALPLSRSFSKLEAAKRNFKLE---EYS
L-SLNTLHQV----------------------------------------------FVEL
TRDAEEHDLE-VASNG-AVEQRRLHP-------------------------
ENSSHAP00000012270 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNERQISVCQQTQALLHTNFLKKWR-----MKR
ESILEWLIS-LLLLLYLF--LFS---KYNQVNHFSELSPM--PLGRVDK--FNDSDLV-V
AYTPISN------TTQKIMDKMATAPFM------------------------------KG
RK--IIPMPNQEAMDAIIPKN-----FSEMVGIIFMNNF-SY----ELKFNWGYRTPIM-
---KE----HLDHSA----------------HCFEM---FGEI-TC-------SLTSY--
WERGFVAFQAAINAAIIEIATNHSVMDMLMAVSGINMKTLPF---------IAQGGFL--
NEIFIFFCIISFSPLIYFASLNI-----------TRDRKNIKEWMTMMGLQSSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGYIFIMATFLAL-----------VTSTHLVVMTGYFVLFILFFLYG
LSVIALAFLLCV----------------------------LIKKPLLT---GLIA-----
FL-LTVFWGC--------LAFTTLYKQLPASLEWILCLLSPFAFSAGMVRIILLDYD---
------LRGVTFPDPSGDSYLILATFSILFFDVLFYLALTLYFDKILPNE---YGRRQSP
LFFLKSSFWFQKQ-KTVHEI--LENEINTEH--YSDCFEPISPEFHGKEAIRIRNIQKEY
-------------KGK------P-----------------------------EKVEAL--
--K--GLLLDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSVPTE--GSATIYNNKLSEITDL
EKIRK-IIGVCPQC--NIQLDFLTARE-NLRLFAKIKGIHPQEVE-QEVQQILTQLEMKN
IQDTLAINLSGGQKR-KLSFGIAILGDPKI--LLLDEPTAGLDPFSRHQVWNLLKER---
---------------KSDHVILFSTQFMDEAD----------------------------
--------------------L---------------------------LADRKVFISSGR
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------I
CDPERI-TSLIKHH--------------------IPDAKL----AAESDEKLVYT--LPL
ER--TNKFPDLYTDLDNCSDQ---------GIVNY--GVSVT----TLNEVFLQLEGK-T
-TDES---------DFGIW-GQE-KIEMT--------RDARCFVELE----QALSSVS--
----E----MI-----------------------TGMALWRKQVCAIARI---------R
LLKLKHE-KKAFLCLLLVFGIGYFPFIMENILYRVFRQ-TNSWGLSPNMYFLSPGQQP--
HTPLTSLLVV-----NN--TGS-NLEDFVHSLKLQNIVLEVVNFR----NKNG-IEDPSY
N-GAIIISGKR-KHYR---FSVACNTKRLNCFP-VL-MGVISNGLLGIFN----------
----------PSEH--IQTKRSTFFHDDV-------------SIGVGFMEASFFCMFIAT
SISPYIAMGSISDYKIKA-QSQLWISG-LYPSAYWCGQ-SLVDIPLY-------------
---CMILFLMYV---INYL--MNNTDEG---WPTSIILFAQILCTIGYAASVVVFTYVIS
FIFRKRRKNSGLWFFCFFII-----SMFLFGIL-FL--NNFEL-LIMLPCMILVPLY---
--TLV--------GCLMLFYGLS----------YNYSKNPDHHEDEIDGISQSSLLVLLI
PYLHIIILLFVLRFLE-MKYGKKSMRKDPVF-RISPSSTEVFPNQEEPEG----EDEDVQ
AERARTTSALA-ALNFD--EKPAIIASCLRKEYEVKKKICFSKSK--KKLATRNVSFCVK
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIRMITGEIRPTAGQVV-LK--GNRS-SLSQQGAD----TIKF
LGYCPQENSLWRNLTVRDHLEVFAAVKGMKKEDAT-----IMISR----LTNVLKLQEHM
NVSVKELSAGIT---RKLCFALSILGNPAVILLDEPSTG----MDPEG-QQQMWKVIRAT
FKNKESGAILTTHYMAEAEAVCDRVAIMVSGQL---------------------------
---------------------------KCIGSIQHLKSK-FGKDYLLEIKVKEPEQVEPL
HAEILKLFPQAA--RQERYSSL--MVYKLPVEVVYPLSQAFSKLEAAKSTFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDLD-VELDT-TVKWKLLPQEEP----------------------
ENSMEUP00000008642 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------INKIASNSFM------------------------------KG
IK--VFGALDQEAIDVIIKQN-----RTEIVGIIFHDTF-SY----ELRFFWGRRIPLI-
---EE-----HKGYG---------------VHCTPH-------ASN-------VYLRY--
WDTGFVTLQAAMNAAIIEITTNHSVMDKMMAVTGMKMKTPPF---------ISKGEIG--
NEVIIFLYIISFIPLIYFASFSV-----------AKERKKAKEWMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGVLY-TGFIFIMANCMAV----------TITYLQLLMITGYFVIFTLFFVYG
LSLVAFAFLLSV----------------------------LIKRPVLS---GSIM-----
IL-LIAFWGA--------LGLVSLHRQLPVSLEWILCLLSPFAFTHGMIQMVWLDCD---
------FKGVTLHDPTGRSQVLIAAIFMLAFDTIFYLALTLYFDKILPXX---XXXXXXX
XXXXXXXXXXXXXXX-XXXX--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
-------------XXX------X-----------------------------XXXXXX--
--X--XLQLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLINILSGLSAPTE--GSASIYNNNLSEMLDL
KEIRR-IIGVCPQF--NVHIDFLTVRE-NLRLYAKIKGVPSKMVE-QEVKRVCLELEMKG
IQDTLAVNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWHLLKEH---
---------------KENRVILFSTQFMDEAD----------------------------
--------------------L---------------------------LAXXXXXXXXXX
XXXXXX--XXXXX---XXXXX---XXXX--XXXXX-X----------------------X
XXXXXX-XXXXXXX--------------------XXXXXXXXXXXXXXXXXXXXXXXXXX
XX--XXXXXXXXXXXXXXXXX---------XXXXX--XXXXX----XXXXXXXXXXXX-X
FDMRGQEQ--------------T-EM--T--------RDAGYFVELE----QALSSVP--
----EM----I-----------------------SGMALWRKQVCAIARV---------R
LLKLKHE-KKAFLCLFLLLAVTLIPIALESILIQIF---YHPHLFSPDMYFLSPGQPP--
QAPLSSLLIV-----NNTXXXX-XXXXXXXXXXXXXXXXXXXXXX----XXXX-XXXXXX
X-XXXXXXXXX-X---------XXXXXXXXX----X-XXXXXXXXXXXXX----------
----------XXXX--XXXXXXXXXXXXXX------XXXDDVSIGVGFMEASFFCMFIAT
SISPYIAMGSISDYKI-KAQSQLWISG-LYPSAYWCGQ-ALVDIPLY-------------
---CLILFLMYV---VNYL---------------------IILCTIGYAASVVVFTYVIS
FIFRKRRKNSGLWFFCFFIX-----XXXXXXXXXXXX-XXXXX-XXXXXXXXXXXXX---
--XXXXX------XXXXXXXXX-----------XXXX--XXXXXXXXXXXXXXXXX--XX
XXXXXX-XXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX----XXXXXXX
XXXXXXXXXXX-XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVV-LK--GKRSSMS-QQDVN----PIKF
LGYCPQENSLWRNLTVRDHLEVYAAVKGMKKEDAT-----IMISR----LANVLKLQEHM
KVSVKELSTGIT---RKLCFALSILGNPAVVLLDEPSTG----MDPEG-QQQM-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSEEUP00000001978 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHMKQKSVYQQTQALLCKNFLKKWR-----MKK
ETTMXXXXX-XXXXXXXX--XXX---XXXXXXXXXXXXXX--XXXXXXX--XXXX-XXXX
XXXXXXX------XXXXXXXXXXXXXXX------------------------------XX
GR--VIGAPNQKDMDNLLIEH-----FPFVAGIIFKDPL-SY----SLKFFQGYNIPFI-
---QE-----DLFSA----------------HCWSF---NNLYVSC-------LLGKY--
WNRGFVAVQTAINAAIIQVMTSHSVTEELMSITATTMRTLPF---------ISKDLFQ--
NEMFILVCLLYFSPLIYFVSLNV-----------TKERKRSKALMKMMGL-DSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GGILFIFSIFISV----------IITATQTIVMTGFMVIFSLFFLYG
LSLMALTFLITV----------------------------LLKKTVLT---NLVI-----
FL-LNLFWGS--------IGFTVYYRLLPSALVWVMSIFSPFAFSAGLSQXXXXXXXXXX
XXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXG---DEHHYSP
LFFLNSSLCFQNQRA-ENKV--IKKEMDLEYL-SDDSFEPLPPEFQGKEAIRIRNVKKEF
-------------KEK------S-----------------------------GKVEIL--
--K--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XSVTIYNKNISEMQAL
EEIRE-ITGFCPQF--NVHFDMLTVKE-NLRLFAKIRGIKRQEVE-QEVQKVLLELDMQN
IQDSLASYLSEGQKR-KLTFGIAILGSPQX--XXXXXXXXXXXXXXXXXXXXXXXXX---
---------------XXXXXXXXXXXXXXXXX----------------------------
--------------------X---------------------------XXXXXXXXXXXX
XXXXXX--XXXXX---XXXXX---XXXX--XLHRN-E----------------------I
CDPEKI-TYLINHH--------------------IPDAKL--K-AELKE-KLVYT--LPL
ER--TDTFPXXXXXXXXXXXX---------XXXXX--XXXXX----XXXXXXXXXXXX-X
XXXXXFRQ--------------G-EM--T--------RDLESLQEVE----S-PSSFT--
----ETSK-IM-----------------------SHMSLWRLQVCAMAQL---------R
FLKLRRG-QKELWTLXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX--
XXXXXXXXXX-----XXXXS---NIEDFIQSLNHQNILLEVDDFE----NRNG-TEDLSY
N-GAIIVSGKR-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLQMFN----------
----------FTQS--IRTERGTFPF-------------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXK-RRTPQLWVSG-LYPSAYWCGQ-ALVDVNLF-------------
---TLIILSVYL---TLFLSIVKYQ------LIPSHVIFNLXXXXXXXXXXXXXXXXXXX
XXXXXXXX-----XXXXXXX-----XX--XXILVITR-NHYTW-SPLITCMVLFPPT---
--TL--------SVYIVLLSQK-----------IHIY--QF--QPQEAHFHAIDFLLSLI
PYFQSLLFIFVLRFME-MKHEKRIMRKDPIF-RISPQR-NPHQNPEEPI----DEDEDVQ
AERIRTATALT-TNLEE--XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXX-XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX
PF00005 // ENSGT00760000118965_1_Domain_5 (2908, 3091)
XXXXXVK-LK--GYNTGW-------------DH
LGYCPQENVLWPHLTVEEHLEVFAAVKGLKKADAV-----IAISR----LVDTFKLYELL
NVPVRKLMAGTT---RKLCFVLSLLGNSSVLLLDEPSTG----LDTVE-QQQMWQTVKAS
IKTTDKGALLITHYLTEAEAICDRIAIMVSGRL---------------------------
---------------------------RCIGSIQHLQSK-FGKYYILELKAKESSQVTLL
HSEILKLFPQAV--QQERYFSF--LIYKLPIADVQPLSQAFHKLETMKHRFNLE---EYS
L-SQSTLEKV----------------------------------------------FFEL
SKEQDQEDFD-EEVDT-TVKWKLLPHSDDP---------------------
ENSMUSP00000045808 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKREINVCQQTWALLCKNLLRKKR-----LKR
DTF
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEFLYT-ALILLSLI--LFL---QLHEVYDFSSLPDV--DLGRIDS--FNDS-TFMI
VYTPITP------TTQRIMDRVSLVSYM----------------------------T--G
RK--ILASPNEENMTELISMR-----FSDVVGVIFTNAY-SY----NLKFIKGARIPTI-
---KE----HQDHTA----------------HCHSY---G-EIIYC-------GLSEF--
WRDGFVALQAAINAAIIEVTTNHSVMEEMMSLTGKYIKIDSF---------VGQEGTT--
TDCFLFFCIIRFSPLTYYISAGV-----------TRERKKMKGLMAVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVIVFVVTLLSTT----------IVKLVQFVFLTGFMVIFSLFFFYG
LSLISLSFLMSV----------------------------LLKKSFLT---DLVV-----
FL-LTVSCGS--------LGFTALYRYLPVSLEWLLSLLSPFAFMLGMVQLLRLDYD---
------VNSNA--DPMGNPNEVIGTIFMLFFDGVFYLLLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSE---YGRRHPP
LFFLKSSFW-SGQNPANRTA--LDNETDYE-F-SDDSFEPVSMEFHGKEAIRIRNLTKDY
-------------IQK------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTK--GWVTIHNNKLSEMTDL
ENISK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIQAHEVD-NEVQRVLLELDMKN
TQNILVQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2367)
AGLDPFSRHRVWNFLKER---
---------------RADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------IPDSKL----SAESEGKLSYI--LPL
ER--TNKFPDLYRDLERSPDL---------GIENY--GVSIT----TLTEVFLKLEGK-S
SIDQS---------DIGMT-EDV-QAGGA--------RSPERFAEVE----QLVSLLN--
----GRCKM-K-----------------------GGMALWWQQLCAVTRL---------R
FLKLKHE-RKSIVILILVLGIGLLHILSANIYRMVRQS-DYCWELAPHMYFLTPGQQP--
QPPLTNLLIV-----NK--TGA-KID
PF12698 // ENSGT00760000118965_1_Domain_4 (2367, 2682)
DFIHSLEQQNIALEVDAFG----TRNG-TEDSQY
N-GAIILSGDE-KNYN---FTLACNTKRLNCFP-VL-VDIVSNGLLGLFA----------
----------PSAH--IQTDRSTFPEEND---HR--KF---DYL-----AYFFLWVLLMA
CVPPYISMTSIDDYKNRA-QFQLWISG-LSPSAYWFGQ-ALFEVPVY-------------
---CALILSIFI---AFYASAPPES-----KFTVGDLF-IQILYVGGYAMSVIFMTYVIS
FIYRKGRKNSGLWSLCFYIV-----SFFSMCFM-LI--DYF
ENSGT00760000118965_1_Linker_4_5 (2682, 2873)
RD-ISLFVLIALVPPA---
--TLG--------GCTLLHFENR----------E-----FSEII-FE-PEREYSYLFFLA
PLLHFAIFVVILRCME-RKFGMKTMRTDPVF-RISPRSDRVFNNPEDPDG----EDEDVS
QERVWTANALT-SADFQ--EKPAIIASCLRKEYKGKKKCFVLKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKMITGETKPSAGQVL-LK--GSST-------GD----TPGF
LGYCPQENALWLNLTVREHLEIFAAIKGMRKSDAN-----VAIER----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FSNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKEYLLEMKVKTPSQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFE-EELDP-SVKWKLLPQEEA----------------------
ENSMNEP00000000510 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTFFQGYSIPLW-
---KE-----EDFSA----------------HCWDG---YG-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ISKNLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------VITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---GERRYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDVEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLREH---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FK-QVEMI--------RDSESLNEME----LAHPSFS--
----EMQTA-V-----------------------SDMHLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAM
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMLN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYFTMGSISDYKKNA-KSQLWISS-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTA-LI--SNFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEMRD----------QQHYRESPE---ANFKLSATDFLVCFI
PYFQTLLFIFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTAREHLEVYAAVKGLRKVDAR-----LAITR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSCLAP00000007143 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNKTQISIYQQTQALLRKNFLKKWR-----MKR
ESSL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGIP-ILLGLYAG--VFS---YFGETIQFPGMPPQ--DLGRVDK--FNSSSIM-V
IYTPVSN------ITQQIMNKTTFAPFM------------------------------KE
ER--IIGVPNKKYMDKLLLQN-----LPHAVGIIFNDTF-SY----KLTVFQG---PLV-
---KE-----DDLSA----------------HCWKG---ND-DFSC-------ILSSY--
WNGGFVPLQSIINAAIIETTTNHPVMEELMSVTAVNMKTLPF---------ISRGILQ--
NEIFILLCLIYFSSFIYFVSLEV-----------TKERKKCKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-AGFIFIISVFITI----------IITSSQIIVMTGFMVIFTLFFLYG
LSLLTLAFLMSV----------------------------LLQKAVLT---NLVV-----
FL-LTLFWGC--------MGFTAFYRQLPSSLEWILNICSPFAFTAGMTQIIYLDYN---
------LSGVTFPDPSGDSYIMIATFAMLAFDCLIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NERHYSP
LFFLNSSSRFQRR-KTVNKI--YEKDRDPEHH-FDDYFESIAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLYFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTVYNKNISEMRDL
EEIRK-MIGVCPQY--NVQFDILTVKE-NLSVFAKIKGIHPPEVE-QKVQEILLELDMQN
IQNNLAKDLSEGQKR-KLTFGIAILGNPRV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2298)
AGLDPFSRHRVWSFLKEH---
---------------RANHVILLSTQFVDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LRCAGS--SVFLK---RKWGL---GYHL--SFYKN-E----------------------R
CDPEQI-TSFIKHH--------------------IPDAKL----KTENKEKLVYS--LPL
ER--TSKFPDLFTDLDKCSGQ---------DMVSY--DISMS----TLSEVFMNVEGM-S
AISQD----------------FE-HAEIL--------SDSENFNERE----PACSSLP--
----EVQKP-V-----------------------GSMELWRMQVCAIARL---------R
FLKLIRG-RKTLLTLLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2298, 2723)
IFGMALFPLLLEEIAYSMIGN-TEDWEIKTELYFLSPGQLS--
QEPRTSLLII-----NH--TES-DIEDFIQSLKHQNILLEVDDFK----NRNG-TESLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKKLHCYP-IL-MNIVSNGLLRMFN----------
----------QTQC--IRTLRSPFVLD-F-------------GIWTGLPEGVFFIFVVAC
CISPYVAMSSVSDYKKKA-KSQLWISG-LYPSAYWFGH-AVVDISLF-------------
---NLILLLMYL---IVCLTNM---RGI---YITSRIIFALVATSFGYAVSLTFLTYVIS
FIFRKRRKSSGLWSFCFYIV-----LNMVF-LL-LF--DYFLL-AVIISSMVFIPLS---
--TLG--------AFIVFLSKR
ENSGT00760000118965_1_Linker_4_5 (2723, 2873)
A----------QEHYIETTE---INFDLSGADLLVCLI
PYFQALLFIFVLRCME-LKFGKKVTRKDPFF-RISPRSPDTRPNPEEP--GG--EDEDVQ
AERIRTSTALT-TSNFH--EKPTIIANCLHKEYAGQKKNCFSKRK--KKLAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFSIK
KGEIFGLLGPNGAGKSSSIRMIAGITKPTAGEVE-LQ--GCGSV-LGEEG-----E-LKF
LGYCPQENVLWPRLTVKEHLETYATVKGLRKGDAA-----IIISR----LMNAFKLHEHL
NVPVGRLAAGTT---RKLCFVLSILGDSPVLLLDEPSTG----IDPAG-QHQMWQAIRMC
VKNTDRAVLLTTHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSVQHLKRK-FGKDYILELQVKEASQVPLV
HTEILKIFPQAA--QQERYSSL--LTYKLPVGDVYPLSQAFHKLEEVKCSFSLE---DYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELGNVD-EEVDT-TMRWKLLPYSDEP---------------------
MGP_PahariEiJ_P0037459 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MKELSVRRQTRALLHKNLLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWGIP-VVIGLYMG--LFS---YFRRSIQVPEVPPQ--DLGSLNE--FNGSSLM-V
VYTPISN------ITQQIMNKTTFAPTM------------------------------KG
TR--IIGVPSTEDLEELLMKN-----VPDVFGVIFNDTY-SY----KLKVFMMYGNPFL-
---K------EDLLA----------------HCWDL---IP-HVFC-------SLSTY--
WKRGFVALQTAINAAIIEVTTNHSVMEELMSVDAINMKTLPF---------ISKEFFH--
YEIFILFCLLYFSSFIHFASRNV-----------TKERKQCKELMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VVFIFIISIFIAI----------IITYTQIIMMTGFLVIFTLFFLYG
LSLIAITFLMAV----------------------------VLQKAILT---NLIV-----
LL-FTLFWGC--------VGFTVLHKELPPSLEWILSICSPFAFTSGMAKIIFQDYN---
------LNGVVFPDPSGESYAMIAVFSILAFDGLLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---AEHRSAP
LFFLNPTSCFR-KTANRNKV--IERDLDPDLP-SDEYFEPVDPAYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA--GSVTVYNKNLSDTQDL
KEVRM-MIGVCPQH--NVQIDALTVKE-NLTLFAKIKGILPQDVA-QEVQQVVSELDMQN
IQDDLAEHLSEGQKR-KLTFGIATLGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2349)
TVGLDPFSRQRIWGFLKER---
---------------RADHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVLISNGA
LKCTGS--SVFLK---RKWGL---GYLL--SLFMD-E----------------------T
CDSERL-TSFINHH--------------------IPDAKL----KAKTKEKLVYI--LPL
ER--TSEFPEFFNDLDKYSGQ---------GLMNY--EVSMS----TLNEVFMNLEGE-P
STTQD----------------FE-KRETV--------TGTESLNEMA----VVYTSLS--
----QVQKT-L-----------------------NTMSLWRTQVCAVARL---------R
ILKLKRD-RKAFLIILLLLGLALLPLGIEYMANTLIEV-KNNWEFKTDSYFLSPGQLP--
QGLRTSLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2349, 2717)
VI-----NN--TES-NIEDFIQSLKHQNIVLEVDDFE----NRNA-TNSLSY
N-GAIIVSGRQ-KDYR---FSVVCNTKRLHCFP-IL-MNVISNGILRMFN----------
----------HTQY--IRIKEDTFPPYMVL------------LFWTGIQEACLFILCAIS
SVSPHIAMSSVSDYKKNA-DSQLWISG-LYPSAYWCGQ-AVVDISLF-------------
---SAMLLTCYV---TSYTSNL---LNI---DITSKIVLSVIVLALGCAASLVFLTYVIS
FVFGKRRKNSGLWSICFFIV-----TVIMLDEF-WA--GSVSE-APVISAMMLVPSF---
--TLN--------GLL
ENSGT00760000118965_1_Linker_4_5 (2717, 2873)
VVLDMKA----------YQHYVEFGE---FKDGLSAADLLLCII
PYIHTLLFIFVLRCLE-VKYGKNVVRKDPIF-RISPRSLKVQPNPEEPID----EDENIQ
AERLRTHNALS-TPNLD--EKPVIIASCLHKEYTGQKKRCCSRRT--RNVAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPDGAGKSSSLRMIAGVIKPTAGQVE-LK--RLRSA-VGRQGDS-----RAE
FGYCPQENVLWPNLTVKEHLELYAAVKGLRKEDAA-----IAISR----LVNAFKLHGQQ
NVQVQNLVAGAT---RKLCFVLSILGNSPVLILDEPSTG----LDVSG-KQQMWQAIQAA
VKDKEKGVLLSTHDLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILELRVKDISRESLV
HREILKLFPQAA--CQDRCFSL--LTYKLPVTDVHPLSQAFHKLEAVKRGFDLE---DYS
L-SPCTLDRV----------------------------------------------ILEL
SKEQELADVY-EEADM-TMRRKLLPPSDEL---------------------
ENSOARP00000015228 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDKVAAAAFM------------------------------KG
RT--ILGIPNEDAMDRVRPKN-----DSEMVGIVFNDTF-SY----RLKFSWGHRVPVV-
---RE----HFEYSD----------------HCWAL---RDEA-FC-------LLSIY--
WQNGFVAFQTAINAAIIEVTANHSVMEELTSVVGINMRTPPF---------ISKGEII--
NEWFIFICIVYFSPFVYVASLNI-----------TKERKRFKKLMTGMGLQQSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWALMY-AGFVSVVSVFMTL----------VIKLFQMIVLTGFMVVVTLFTLYG
LSLIALAFLLCV----------------------------LIKRPILT---GVVA-----
SL-FTVFWGC--------LGFTALYRQLPSSLGWALCLFSPFAFTAGVAQISHQEYH---
------VSAVVFPDPSGESNTMILVFFLLAFDTLLYLTLTLYFEHILPDE---NGQRRSP
LFFLKSSFWSQRK-STHREV--FGNEMNSELS-CGDSFEPVPPEFHGKEAIRIRNLKKEY
-------------KGK------P-----------------------------GTVEAL--
--QETGICLDVYEGQLTAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLSILGGWSTCTE--GSATIYNTQLSEIMDM
EEIRN-YTGFCPQF--NIYFDFLTVRE-NLRLFAKIKGIPAKEVE-QEVKGIVMELDMHS
IQDVIAKELSSGQKR-KLTFGIAVLGDPQV--LLLDEPTAGLDPFSRHLVWNFLKER---
---------------KTNHTILFTTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LRCAGS--SLFLK---RKWGI---GYHL--SLHRD-E----------------------R
CSTERI-TSLITQH--------------------ISDAKL----TAESEERLVYT--LPL
ER--TDRFPDLCRGLENSSDQ---------GIMNF--GVSMT----TLTEVFLNLKGR-S
AIDEP---------DPRVG-GPA-GIVVT--------PGPGAQSDIP----QALRSLP--
----GVETA-A-----------------------SSAALWRRQVCAVARL---------R
FLKLRNE-RKIFLSLLVVFGIALIPTVCERIVFSVLFR-DHCWEFSPGMYFLSLEQLP--
QAPLTDLLII-----NN--TGS-SIEDVVQSLKRQGLILEVDDAR----NRNG-SDDPSY
N-GAIIVSGGR-KDYR---FSVACNTKRMNCFP-VL-IGIVSNALLGIFN----------
----------VTEL--IKTERSTFPPDDP-------------RWAIGLLD--FLLLLVVN
CLSPYVGMSSVSDYKQKA-QSQLWISG-LCPSAYWCGQ-ALVDIPFY-------------
---FGILVSVHL---MYY-IFL----ES---SIVLEFLFALVVCVAGCAACLTLLTYVIS
FLFPTGRKNNGFWALSFFLI-----SLFMLILL-GL--THAEN--IIILCIILIPSC---
--TSV--------FFLARMIELS----------SMYHRRSESQDSEESAVDEIMLLAVFI
PYLQIIIFLFIMRCLE-MKYGKETMRKDPFF-RISPRRREYRPNPEEPEE----EDEDVH
RERVKTANALA-ASGSD--EKPVILASCLRKEYTQKRKRCFSARR--TKTAVRNVSFCIN
KGEVLGLLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3038)
STSVKMVTGDTAPTAGVVR-GV--GGSP-AHSWGTSC----SVSA
A--SSRSSHQSVSLTVREHLDLYAAVKGLAKDEAA-----LSVSR----LADALQLQDQM
ALPTKALPEGAK---RKLSFALSILGSPAVLLLDEPTTG----MDPEG-QLQMWQAIQAL
VKSSARGALLTTHSMAEAEAVCDRVAVMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEVKVKALSLVEPL
HTEIFKLFPQAA--RQERYSFV--MAYKLPIEDVHPLSQTFSKLEAVKQAFDLE---EYS
L-SQATLEQV----------------------------------------------FLEL
SKEQELGNMD-DDVDT-TVRWKLLPQEES----------------------
ENSMODP00000007705 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRERQISVCQQTKALLYTNFLKKWR-----MKR
ESLLEWLIS-LLLLLHLF--LFA---KYNQVNRFSELSAM--SLGRVDK--FNDSDLV-V
AYTPISN------TTQKIMDKMAAAPFM------------------------------KG
RK--VIGMPNQEAMDTLIPKK-----YSEMVGIIFTDNF-SY----ELKFNWGYRTPVM-
---KE----HLDHSA----------------HCFET---YGEI-TC-------SLTSY--
WERGFVAFQAAINAAIIEMATNHSVMDMLMAVSGINMKTLPF---------IAQGGFL--
NEIFIFFCIISFSPLIYFASFNV-----------TRDRKNIKEWMTMMGLQSSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGYILIMATFLAL-----------VTSTHLVIMTGYFVLFTLFLLYG
LSLVAFAFLLCV----------------------------LIKKPLLT---GLIA-----
FL-LSVFWGC--------LGFATLYKQLPTSLEWILSLLSPFAFSAGMVQIVLLDYD---
------LRGVTFPDPSGDSYLILATFSILLFDILLYLALMLYFDKILPNE---YGRRESP
LFLLKSSFWFQKQ-KFVHEV--LENETNPEY--YSDFFEPISSEFHGKEAIRIRNIRKEF
-------------KGK------L-----------------------------KKVEAL--
--K--GLQLDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLIVPTE--GSATIYNNNFSDKTDL
EEIRK-IIGVCPQF--NVQFDFLTMRE-NLRLFAKIKGIQPQKVE-QEVQRVVMELEMKN
IQDVIAENLSGGQKR-KLTFGIAILGDPQI--LLLDEPTAGLDPFSRHQVWNLLKEH---
---------------KSKKVILLSTQFMDEAD----------------------------
--------------------L---------------------------LADRKVFMSKGQ
LKCAGS--SLFLK---KKWGI---GYHL--SLHKNIQ----------------------I
CNSETI-TSLIKHY--------------------IPDAKL----KEENEEKLVYT--LPL
ER--TNKFPDLYRDLDSCIGQ---------GIVHY--GVSMM----TLNEVFLKLEGK-T
ATDEA---------DFGNW-VQA-QTEMS--------RNSEGSVELN----EAFSSFS--
----GRREVTL-----------------------GSMALWRRQVCAIGRL---------R
FLKLKHD-KKAFLCILLLFGVASIPYIVEEIVFNRFHQ-STAWRLSPKSYFLSPGQYP--
QSPLTSLLVI-----NN--TGS-NIEDFIDSLKHQNIVLELKDFE----KENG-TDDPSY
N-GAIIVSGEK-KDYR---FSVACNTKRLNCFP-VL-VDVISNGLLKMFN----------
----------SSKQ--IQTTRNIFPHITV-------------LLDLGYLDSNVFWQLMAT
SISPYIAISSIYDYKIRA-QSQLRISG-LYPSAYWCGQ-ALVDIPFY-------------
---FLILIVINI---PISITKYKNIPEF---SPDIAVEFAKVLSSIGYAASIISFMYIIS
FIFRNGRKHSSIWCLCFFSV-----SILLTKIL-EI---KYKF-SQILLCTILIPFF---
--TLI--------GINGYVLEFY----------Y-YSK--RIKEDNDDEMSEDIFFIILL
PYLHCIIFVFILRYLEKMKYGKNLLRMDPVF-RMFPSSKDASPNPEEPED----EDEDVQ
EERERTSRALT-TSNLD--EKPAIIASCLRKEYEGKKKSCFAKKK--KKLATRNISFCVK
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3036)
STAIRMITGEIRPTAGKVV-LK--RKSI-DTSQQRDE----MFQF
LGYCAQENTLWKNITVREHLELYAAVKGINKEDAT-----AIISR----LVDALTLKEYM
KFPVNKLSPGIK---RKLCFALSMLGNPAIVLLDEPSIG----IDPEG-QQQIWQAIRAT
FKKKERGAILTTHYMAEAEAVCDRVAIMVSGQL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEIKIKDPLQMMPL
HTEILKLFPRAA--RQERYSSL--MVYKLPMEDIQPLSQAFSKLEAAKHTFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKDQELGDFE-EELDT-TVKWKLLPQEEP----------------------
ENSPEMP00000007752 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVNREINVCQQTWALLCKNLLRKWR-----MKR
DTFWEFLYT-SISLFSLS--IFP---EIHNI
PF12698 // ENSGT00760000118965_1_Domain_0 (572, 1542)
YDFSSLSNV--DLGRIDS--FNDS-TFLI
AYTPVTE------TTQRIMNRVSLASYM----------------------------T--G
KE--ILAFPDEENMTELISNR-----YNDVVRVIFTSTY-SY----HLKFHEGIRIPTM-
---KE----HKDHTA----------------HCSAY---E-DDIIC-------DVSRF--
WTDGFVALQAAINSAIIEITTNHSVMEEMMSVTGKYMKIDPF---------IAQGGIT--
TDSFLFLCIICFSPLTYYISAGV-----------TRERKKMKGLMTVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVIVLIVALLLTF----------IIKLVQFVILTGFMMIFSLFFFYG
LSLISLSFLMSV----------------------------LLRKLFLT---DFVV-----
FF-LTVFSGS--------LGFTALYRYLPVSLEWVLSLLSPFAFMLGMAQLLHLDYD---
------VNSNA--NPQGNPNLIIATIFMLFFDSVFYLILTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPNE---YGRRHPP
LFFLKSSFWSQQNQADQIAL--DNETADYE-F-SDDLFEPVSTEFHGKEAIRIRSLTKEY
-------------IEK------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLALDIYKGQITAILGHSGAGKSTLLNVLSGLCVPTK--GCITIYDNKLSEMTDL
ENIIK-LTGICPQC--NVQFDFLTVRE-NLRLFAKIKGIQAHEVD-NEIQRVLMELEMRN
IQDILAQNLSGGQKR-KLTFGIALLGDPQI--FLLDEPTAGLDPFSRHRVWNVLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCVGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CVHERI-TSLVKQH--------------------IPECKL----SAKSEGNLNYI--LPL
ER--TNKFPDLYRDLERCPDL---------GIENY--GVSIT----TLNEVFLKLEGK-S
TIDQS---------DVNVS-E----AAGT--------RGTGRLAEME----QLVSLLN--
----AASNR-K-----------------------GGMALWWQQLCAVVRL---------R
FLKLKHE-RKSVFFLILILGIGLLHILSANIHRIVRDS-DYCWELSPYMYFLSPGQQP--
HEPLTNLLII-----NK--TGA-QIDDFIHSLEKQNISLDVDAFG----TRNG-TEETLY
N-GAIILSGGE-NNYN---FMLVCNTKRLNCFP-VL-VDIVSNGLLGLFT----------
----------SSAH--IQTDRSTFPEDNS---YG--PF---FHL-----PYFFSCILVMA
SVPPYISMTSIDDYKNRA-QLQLWISG-LCPSAYWFGQ-ALVEVPIY-------------
---WALTSSMYV---AFYASA-QES-----ILATGDLF-IQMLYVGGYAMSIIFMTYVIS
FIYHKGRKNSGIWSLCFYFV-----TLFSIYFM-IL--GPFPD-EFLFCAITLIPPA---
--TLA--------GCTFLHLQNS----------Q-----FYDIG-LEESSRDYSFLLFLV
PFLHFAIFLAILRCLE-SKLGMKTMGMDPVF-RISSRSGHVFNNPEEPEG----EDEDVR
LERVRTASALT-SADFQ--EKPAIIASCLRKEYRGKKKCFVFKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEIVGLLGHNGAGKSTSIKMITGEAKPSAGQVL-LK--GNST-------GD----TLGF
LGYCPQENALWPSLTVREHLEIFAAMKGMSRGDAA-----VAIAR----LADVLKLQEQM
KAPVKTLSEGVK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQIWKIIRAI
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLAQVEPI
NTEIMRLFPQAA--RQERYSSL--MVYKLPKEDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFE-EELDP-SVKWKLLPQEEA----------------------
MGP_PahariEiJ_P0037450 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKREINVCQQTWALLCKNLLRKKR-----LKR
DTFLEFLYT-ALILLSLT--LFL---ELHEVHD
PF12698 // ENSGT00760000118965_1_Domain_0 (574, 1542)
FSSLPDV--DLGRIDS--FNDS-TFTI
AYTPVTP------ITQKIMDRVSLVSYM----------------------------T--G
RK--ILAFPNEENMTELVSMH-----YDDVVRVIFTNAY-SY----HLKFMTGTRIPII-
---KE----HQDHTA----------------HCYSY---G-EIISC-------GLSGF--
WKNGFVALQAAINAAIIEVTTNHSVMEEMMSLTGKYIKIDSF---------IGQEGTM--
TDFFLFLCIICFSPLTYYISAGV-----------TRERKKMKGLMAVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVIVFVVTLLLTF----------IVKLVQFVFLTGFMVIFNLFFFYG
LSLISLSFLMSV----------------------------LLKKSFLT---DLVV-----
FL-LTVSCGS--------LGFTALYRYLPASLEWLLSLLSPFAFMLGMVQLLRLDYD---
------VDSNA--DPMGNPNEVIGTIFMLFFDGVFYLILTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSE---YGRRQPP
LFFLKSSFWS-RQNPANRTA--LDNETDYE-F-SDDSFEPVSTEFHGKEAIRIRNLSKDY
-------------IQK------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTK--GWVTIQDNKLSEMTDL
ENISK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIQAHEVD-NEVQRVLLELDMKN
TQDILVQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2377)
AGLDPFSRHRVWNLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------IPDSKL----SAESEGKLSYI--LPL
ER--TNKFPDLYRDLERCPDL---------GIENY--GVSIT----TLTEVFLRLEGK-S
SIDQS---------DIGVT-EDV-QAGGA--------RGPGRRAEVE----QLVSLLN--
----GRSKM-K-----------------------RGMALWWQQLCAVTRL---------R
FLKLKHE-RKSIVILILILGIGLLHILSANIHRIVRQS-DYCWELTPHMYFLTPGQQP--
QLPLTNLLIV-----NK--TGA-KIDDFIHSLEQQN
PF12698 // ENSGT00760000118965_1_Domain_4 (2377, 2686)
IALEVDAFG----TRNG-TEDSQY
N-GAIILSGDE-KNYN---FTLACNTKRLNCFP-VL-VDIVSNGLLGLFT----------
----------PSAH--IQTDRSTFPEEND---HR--KF---DFM-----AYFFSWVLLMA
SVPPYISMTSIDDYKNRA-QFQLRISG-LSPSAYWFGQ-ALLEVPVY-------------
---WALILSMFI---AFYASAPPES-----KFTARDLF-IQILYVGGYAMSIIFMTYVIS
FIYRKGRKNSGIWSLCFYIV-----SFFSMCFM-LI--DFFND-T
ENSGT00760000118965_1_Linker_4_5 (2686, 2873)
TLFGFIALVPPA---
--TLV--------GCILLHFENR----------E-----FSEIL-FE-SEREYSYMFFLA
PLLHFAIFIVILRCME-RKFGMKTMRMDPVF-RISSRSERVFNNPEDPEG----EDEDVS
QERVWTANALT-SADFQ--EKPAIIASCLRKEYKGKKKCFVLKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKMITGETKPSAGQVL-LK--GNST-------GD----TPGF
LGYCPQENALWLNLTVREHLEIFAAIKGMRKSDAN-----MAIER----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FANTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKEYLLEMKVKTPSQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDRFE-EELDP-SVKWKLLPQEEA----------------------
ENSFDAP00000021413 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MGKRHKSVGRQMWTLLCKNCLKKWR-----MKR
ETTLEW
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
FFS-FLLLLFSF-LFSS---NLHQVNDSSQMPAM--DLGRVDS--FNDS-NYIV
AFAPESK------TTQEIMNKVASAPFM------------------------------KG
RT--IMGWPDEESMTELDLNY-----STDAVRVIFSDMF-SY----HLKFSWGHRIPKI-
---KE----HKDHSA----------------HCQVV---D-EKIIC-------ESSMF--
WEKGFVAFQAAINAAIIEITVNRSVMEELMSITGVNMKILPF---------IAQGGIT--
TDFFIFFCIISFSSFIYHLSVNV-----------AQERHYIKSLMTMMGLQGSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGVMY-AGFILVMAVLMTL----------IVKSTQIIVLTGFMVVFILFFLYG
LSLITLAFLMSV----------------------------LIKKPHLT---GLAI-----
FL-LIIFWGS--------LGFTTLYRHLPAFLEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNVHLDASNNSYIVIATLFMLAFDALLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTQ---YGHRHSA
MFFLKSSFWSKYQRA-DHVV--LENEIDSDPS-SNDAFEPVSAEFHGREAIRIKNLKKEY
------------K-GQ------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDIYEGQITALLGHSGAGKTSLLNLLSGLSLPTS--GSITIYSHTLSERADF
ETVSK-LTGVCPQS--NVQFGFLTVRE-NLRLFATVKGILPHEVE-EEVQQILRDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPLSRHHIWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISHGR
LKCAGS--SLFLK---KRWGI---GYRL--SLHLN-E----------------------M
CDPESI-TSLVKQH--------------------IPDATL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCPNK---------GIENY--GVSMT----TLNEVFLKLEGK-S
TIDES---------DVAIW-GQL-QSDGT--------KDMASLVELE----QVLSSLH--
----VTRKI-A-----------------------GGMALWRQQLCAIAKV---------R
FLKLKNE-RKSLLAMLLLLGISFFPQLLEHLFYELYQK-SYTWDLSPDMYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-SIDDFVQALGQQNIALEVDALG----TRNG-TEEPSY
N-GAITVSGDA-EDHR---FSIACNTKRLNCFP-VL-IDIISNGLLRTFN----------
----------STEH--IQTDRSTFFAEHMS-------Y-DFEYL-----SSAFFWIPLAA
CFTPYIAMSSIDDTKKKI-HSQLWISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYVFSPEEI-----IFIIQNLL-I--------------------
------------------QV-----TIFTIFATDL---SEYTF-LGLFFCTILIPPF---
--TLI--------GSLFIFSEIS----------YDS------MDYLGASESQIVFLALLI
PYLQFFIFLFVLRCLE-GHFRKKSLRKDPVF-RISPRSSDVFPNPEEPEG----EDEDVH
MERIRTANAMA-ALDEE--EKPVIIASCLRKEYAVKKKNCFSRKK--KKLAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVVGLLGHNRAGKSTVIKMITGDIKPTAGQVI-LK--RSSE-------GD----TLGF
LGYCPQENVLWPSLTVREHLEVYAAVKGLKKRDAM-----VTITQ----LVEALKLQDQL
KTPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRRMERGALLTTHYMAEAEAVCDRIAIMVAGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVRTPTHVEPL
HEEILRLFPQAA--RQERYSSL--MVYKLPMEDVQPLSRTFSKLEIVKQSFGLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFE-EALGA-SVKWKLLPQDEP----------------------
ENSECAP00000005857 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MKRKSVYQQTQALLCKNFLKKWR-----MKR
ESAWEWGFP-ILLGLYMG--LFS---NLKENRHFPEMPPQ--DLGRVDK--FNSSSII-V
VYTPISN------ITQQIMNKTALAPFL------------------------------KG
RR--VIGAPNPKHIDELLLDN-----FPYVVGVIFNDTF-SY----KLKFIQGYAIPFL-
---KE-----EVFSA----------------HCWDT---RY-GFSC-------SLAKY--
WNRGFVTLQAAINAAIIEITTNHSVMEELMSVTAINMKTLPF---------ISKNILQ--
NEMFIFCCLLYFSPFIYFLSFSV-----------TKERKKSKDLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIMITT----------IITSAQIIVMTGFMVIFTLFFLYG
LSLIALAFLMSV----------------------------LLKKTVLT---NLVV-----
FL-LTLFWGC--------MGFTTFYRQIPSSLEWILSIFSPFAFTAGLTQIIHLDYN---
------MNGVIFPDPSGESYKMIATFSVLAFDALFYLVLALYFDKILPYG---NERQNSP
LFFLNSLSCFQHQ-RTDNKF--IEKEIDPEHP-SDDYFERVAPEFQGKEAIRIINVKKEY
-------------KGK------S-----------------------------GKV
PF03193 // ENSGT00760000118965_1_Domain_2 (1676, 1718)
EAL--
--K--GLLFDIYEGQITAIVGHSGAGKSSLLNILNGSSLPTE--GSITIYNKNLSEMQDMEEIRK-ITGICPQV--NVQFDILTVKE-NLRLFAKIKGIQPQEVE-QEVQKVLLEMDIENIQDNLAEHLSEGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWSFLKER------------------KTDRVILLTTNFMDEAD------------------------------------------------I---------------------------LADRKVIMSNGRLKCAGS--SVFLK---RRWGL---GYHL--SLYTN-E----------------------ICDPEKI-TSFINRH--------------------IPDAKL----KAESKEKLVYT--LPVEK--TNKFPDLFSDLDKGSGQ---------GVMSY--DVSMS----TLNEVFMKLEGK-SAFEQD----------------FE-QAEMT--------RDTESLHNMD----LARSSFP------EMQEA-L-----------------------SDMGLWKMQVCAIAWL---------RFLKLKRG-KKALLALLLVFGIAIFPLIVEKILFAVVSQ-KSDWEFKPELYFLSPGQLP--QDSRTSLLII-----NN--TES-DIEDFIQSLKHQNILLEVDDFE----NRNG-TDDLSYN-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIVSNGLLRMFT--------------------HTQP--IRTERSSFRLNYV-------------LLWAEMLEGSIFFFLVVCSISPYIAMSSVSDYKKRA-KSQLWISG-LYTSAYWCGQ-ALVDTTFF----------------AFILLLMYL---IFYIANM---GHI---YITSRIVFALVVITLGYAISLVFLTYVISFIFRKRRKNSGLWAFSFSFV-----NIFQFEKY-SG--WPGDA-AFKFAHSALVALE-----MLP--------TVLLILNMQP----------MQHQDNIQH---PNYDLSGADFLLCLIPYFQALLFVFVLRCME-IKCGKKIMQKDPVF-RISPQSRNAPPNPEESVD----EDEDVQAERIRTATALT-TSNSE--EKPVIIASCLHKEYAGQKKNCFTKRK--KKIAARNISFCVKKGEILGLLGPNGAGKSSSIKMISGVMTPTAGKVE-LK--GSSSD-WDHQGDD----TLKFLGYCPQENVLWPNLTVKEHLEVFAAVKGLRKGDAS-----AAISR----LVDTFKLHDQLNVLVRELTAGAT---RKLCFVLSILGDSPILLLDEPSTG----MDPTG-QQQMWQTIQKAIKNTERGALLSTHYLAEAEAVCDRVAIMVSGRL------------------------------------------------------RCVGSIQHLKSK-FGKDYILELKLKESSQVTLVHVEILKLFPQAV--QKERFSSF--VLYKLPVADAHPLSQAFHKLEAVKYNFNLE---EYSL-SQCTLEKA----------------------------------------------FLELSKEQELGNFA-EEVDT-SMRWKLLSHSEDP-----------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLNILNGSSLPTE--GSITIYNKNLSEMQDM
EEIRK-ITGICPQV--NVQFDILTVKE-NLRLFAKIKGIQPQEVE-QEVQKVLLEMDIEN
IQDNLAEHLSEGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWSFLKER---
---------------KTDRVILLTTNFMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---RRWGL---GYHL--SLYTN-E----------------------I
CDPEKI-TSFINRH--------------------IPDAKL----KAESKEKLVYT--LPV
EK--TNKFPDLFSDLDKGSGQ---------GVMSY--DVSMS----TLNEVFMKLEGK-S
AFEQD----------------FE-QAEMT--------RDTESLHNMD----LARSSFP--
----EMQEA-L-----------------------SDMGLWKMQVCAIAWL---------R
FLKLKRG-KKALLALLLVFGIAIFPLIVEKILFAVVSQ-KSDWEFKPELYFLSPGQLP--
QDSRTSLLII-----NN--TES-DIEDFIQSLKHQNILLEVDDFE----NRNG-TDDLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIVSNGLLRMFT----------
----------HTQP--IRTERSSFRLNYV-------------LLWAEMLEGSIFFFLVVC
SISPYIAMSSVSDYKKRA-KSQLWISG-LYTSAYWCGQ-ALVDTTFF-------------
---AFILLLMYL---IFYIANM---GHI---YITSRIVFALVVITLGYAISLVFLTYVIS
FIFRKRRKNSGLWAFSFSFV-----NIFQFEKY-SG--WPGDA-AFKFAHSALVALE---
--MLP--------TVLLILNMQP----------MQHQDNIQH---PNYDLSGADFLLCLI
PYFQALLFVFVLRCME-IKCGKKIMQKDPVF-RISPQSRNAPPNPEESVD----EDEDVQ
AERIRTATALT-TSNSE--EKPVIIASCLHKEYAGQKKNCFTKRK--KKIAARNISFCVK
KGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSIKMISGVMTPTAGKVE-LK--GSSSD-WDHQGDD----TLKF
LGYCPQENVLWPNLTVKEHLEVFAAVKGLRKGDAS-----AAISR----LVDTFKLHDQL
NVLVRELTAGAT---RKLCFVLSILGDSPILLLDEPSTG----MDPTG-QQQMWQTIQKA
IKNTERGALLSTHYLAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCVGSIQHLKSK-FGKDYILELKLKESSQVTLV
HVEILKLFPQAV--QKERFSSF--VLYKLPVADAHPLSQAFHKLEAVKYNFNLE---EYS
L-SQCTLEKA----------------------------------------------FLEL
SKEQELGNFA-EEVDT-SMRWKLLSHSEDP---------------------
ENSCANP00000036201 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YQQMVGVIFRDTF-SY----QLKFNWGYRIPII-
---KE----HSEYIE----------------HCWAM---HGEI-FC-------YLAKY--
WLNGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFLFTCLVSFSSFIYFASLNV-----------AKERGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFVFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLHRQLPLSLGWVLSLLSPFAFIAGMAQITHLDNY---
------LRGVIFPDPSGDSYIMIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITDM
EEMRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2440)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GVSMT----TLNEVFLNLEGK-S
AIDEP---------DFDIG-KRK-KIHVT--------RNTGNESKME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKAFRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTNKLNCFP-VL-MG
PF01061 // ENSGT00760000118965_1_Domain_4 (2440, 2648)
IVSNALIGIFN----------
----------FTEL--IQTESTSFSRDDI-------------VLGLDFIDGSIFLLLITN
CISPFIGMSSISDYKKKV-QSQLWISG-LWPSAYWCGQ-ALVDIPLH-------------
---FLILLSIHL---IYYFIFL----GF---QFSWERTFVLVVCIIGCAASLIFLTYVLS
FIFHKWR
ENSGT00760000118965_1_Linker_4_5 (2648, 2873)
KNNGFWSFDFFII-----LICVSTIL-VS--TQYEN-LNLILCMIFIPSF---
--TLL--------GYVILLIQLD----------FIYMTNLDSLDSIINEVNKTILLTTLI
PYLQSVIFLFVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQVANILT-TPNLA--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMIAGYTKPCAGAVV-LQ--DSRT-LVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMISGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPSQVEAL
HTEILKLFPQAA--RQERYSSL--MAYKLPVEDVHPLSRAFFKLEAVKQTFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSOPRP00000010611 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MTPKQRSVYHQTRALLQKIVLNKWR-----VRR
ESLLELGVA-ILIGLYMG--VFS---YFKENNRVPEIPPQ--NLGRVDK--FNSS-SLKI
FYTPVSN------MTQQIINQTEFSPYL------------------------------KG
VS--VAEALNEKHMDTLLQEN-----IPNAVGIVFNDTF-SY----KLKFFNGYHVPFV-
---KE-----EDFSG----------------HCWNG---YS-ETSC-------SLITY--
WTRGFVTLQTVLNAAIIEIITDHPVVDELMSVTAINMKTLPF---------ISKDVFQ--
NELFIFFSLLYFSPFIYFLTINV-----------TRERKKYKGLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLVY-AGFIFLGSIFIAI----------IITSTQIIVMTGFVVIFTLFFLYG
LSLXXXXXXXXX----------------------------XXXXXXXX---XXXX-----
XX-XXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXX
XXXXXXXXXXXXXXX-XXXX--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
-------------XXX------X-----------------------------XXXXXX--
--X--XXXXXXXXXXXXXXXXXXXXXXX
PF00005 // ENSGT00760000118965_1_Domain_3 (1709, 1979)
SSLLILNGLSVPTR--GSVTIYNKNLSEKQDL
EEVRK-KTGICPQF--NVHFDMLTVKE-NLSLFAHIKGIHPQEVE-QEVRQILLELDMQD
VQDNLAKHLSEGQKR-SLTLGIAILGDPQV--LLLDEPTAGLDPFSRHRVWSLLRER---
---------------RADRVILFSTHLMEEAD----------------------------
--------------------L---------------------------LAXXXXXXXXXX
XXXXXX--XXXXX---XXXXX---XXXX--XLQKN-E----------------------I
CDPEQI-ILLINHH--------------------IPDAKL--K-TENKE-KLVYT--LPL
EK--TNKLPGLFGDLEKCLGK---------GVAGY--DISMP----SLSEVFMKLEGR-T
TVRQDFEH--------------P-QK--I--------KDSESLNDMG----AASSCFP--
----EMQK-TV-----------------------SGMGLWRMQICAIAWL---------H
FLKFKRG-RKLFLTLLLILGIAVFPLIVEMIVLAITNT-KTDWELKTDLYFLSPGQLP--
QDPRTSLLIL-----NNTXX---XXXXXXXXXXXXXXLLEVDDFE----NRNG-TSELSY
N-GAIIVSGKQ-KDYR---FSVVCYT-RVHCFP-IL-MNIISNGLLRMFN----------
----------HTQS--IRIERGLYPH-------------SYLMFWTGLPEGSTFLLFLAC
SISPYIAMSSVSDYKR-KAKSQLWVSG-LHPSAYWCGQ-ALLDINLL-------------
---TFIILSTFL---IFYIVNMDHV------YISSRIVFAVVVFSFGYGASLVFLTYVIS
FIFRKKKKHSGFWSFCFYIV-----FN--ITLSISVF-CHLDL-TVIIINMILVPSS---
--TM--------GGFLLFLNDX-----------XXXX--XXXXXXXXXXXXXXXXXXXXX
PYFQALILIFVLRCLE-MKCGNKIMQKDPVF-RMSPQNRGIRPNPEEPI----DEDEDVQ
AERIRTATTST-TSRLD--EKPVILARCLHKEYAGLKKNCCSKRK--MKTAVKNVSFCIK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GETLGLLGPNGAGKSSSMRMMCGITKPTSGEVE-LK--GYTSVI-------------SH
LGYCPQENGLWAMLTVKXXXXXXXXXXXXXXXXXX-----XXXXX----LVDALNLREQL
NVTVQKLTTGST---RQLCFVLSILGDPPVLLLDEPSTG----MDPTG-QQQMWQAIRAA
VRTSERAVLLTTHSLVEAEALCDRLAVMVSGRL---------------------------
---------------------------RCIGSIEHLKRK-FGKGYILELKVKEPSQVTLL
HMEILKLFPQAV--QQTRYYPL--LTYKLPLADVCPLSQAFHKLET--------------
------------------------------------------------------------
---------------------------------------------------
ENSJJAP00000009414 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MKEISLYQQTKALLHKNFLQKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWSLP-ILIGLYMG--LIS---DISENIRLPELPPQ--DLGRVDK--FNSSSAM-I
VYTPISN------TTQQIMNKTVFASFM------------------------------QD
AT--IIGAPNKTHMDKLLLEN-----FPHAMGVIFQDTF-SY----KLKLILGYGIPLF-
---KE-----ESLPA----------------HCWNL---YS-GFSC-------PLSTY--
WTRGFVALQSVLNAAIVEITTNHSVMEELTSVTAINMKTLPF---------ISKDLLQ--
NEIFILLCLLYFSPVIYFVSLNV-----------TKERKQRKDLMTMMGLQNSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGVIFITSIVITI----------VITSSQIIVLTGFMVIFTLFFLYG
LSLIALTFLMSV----------------------------LLQKAGLT---NLIM-----
LL-LSLLWGC--------VGLTVLYRQLPSSLQWILSIFSPFAFSAGMAQIIHLDYN---
------LNGVVFPDPSGDSYVMIATYSILAFDGLIYLILAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPHG---DEHRSSP
LFFLNSPSCFQHG-KTNNRA--IEKDIDLELP-TDD-FEPIASEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFFDIYESQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
KEIRK-ITGVCPQH--NVQFDALTVKE-NLHLFATVKGIHPGEVA-REVQKILLEMDMQP
IQDNLAESLSEGQKR-KLTFGIAMLGEPRI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2368)
TVGLDPFSRQRVWSFLNER---
---------------RANRVILLSTQFVDEAD----------------------------
--------------------I---------------------------LADRKMIMSSGS
LKYAGS--SVFLK---RKWGL---GYHL--SLYRN-E----------------------A
CDPEQI-TSSITHH--------------------IPDAKL----KIKNKEKLVYT--LPL
ER--TNKFPDLFSDLEKYTGK---------DMMGY--DVSMS----TLNEVFMNLEGE-S
TTKPG----------------K--------------------------------------
------------------------------------------------------------
-------------NQLLIFGIGLFPLIMEKQAHSMVDE-GADWEFKTELYFLSPGQLP--
QDLRTSLLII-----NN--TES-NIED
PF12698 // ENSGT00760000118965_1_Domain_4 (2368, 2666)
FIQSLKHQNILLEVDDFE----NRNG-TEGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRVHCFP-VL-MNVISNGLLRMFN----------
----------QTQR--IRIERSSFSFVS-------------------VRYGSIFLLFVVC
SISPYIAMSSASDYKRKA-DSQLWVSG-LYPSAYWCGQ-AIVDISLF-------------
---NLIFSLMYL---IFYITKI---IE-----------MSTAIFSFGYAASLIFLAYLIS
FIFCKRRKNNGLWSLCYYIL-----
ENSGT00760000118965_1_Linker_4_5 (2666, 2873)
SL---------------------------------
------------------------------------------------------------
-----------------------LMRKDPVF-RISPRSPDVQPSPEYPTD----EDEDVQ
AERARASAALS-TSSSD--EKPGIIASCLYKEYTGHWKSCFSKKK--KTVAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGPNGAGKSSCIKMIAGITKATSGEVE-LSAGSPA---GARQRD------ALR
CGYCPQQNALWPSLTTKEHLQVYAAVKGLRKEDAA-----AVIHR----LVGGFKLQEQL
DVPVRNLAAGAT---RKLGFALGVLGNAPVLLLDEPSTG----ADPAG-RRRMWQVIQAA
VKNTERSVLLITNDLAEAEAVCDRVAVMVSGRL---------------------------
---------------------------RCIGSIQHLKKK-FGKDYILELKVKEPSSEPLV
HTEVLKLFPQAA--RQERCFAS--LTYKLPIADVYPLSEAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------ILEL
SKEQELGNDD-EDIDT-TMRWRLLPHSDEP---------------------
ENSMPUP00000014240 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKRHLSVGQQTWALLCKNFLKKWR-----RKR
ETLLEWFFS-FLLVLFAY-RLSS---NLHQVNDFPQLPAM--NLGRVDN--FNDS-NYVI
AFAPESK------TTQEIMEKVASAPFM------------------------------KG
RR--IMGWPDEKSMDDLDLNY-----SIDAVKVIFNNTF-SY----HLKFVWSGRIPKM-
---KE----HRDHSA----------------HCQVM---D-EKITC-------EGSMF--
WKKGFIAFQAAINAAIIEITTNHSVMEELMSITGINMKILPF---------VAQAGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYMKSLMMMMGLQESS------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFIVATLMAL----------ITKSAQVVVLTGFMAVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRHLPAFLEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNIHLDSSDNPYLIIATLFMLVFDGLLYLALTLYFDKILPTE---YGHRHSP
WFFLNSSFWFQHQRA-DHVA--LENEIDSNSS-SNDSFEPVSPEFHGKEAIRIRNLKKEY
------------RKGK------H-----------------------------EKVEALKV
ITP--GLVFDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNMLSGLSLPTS--GSVTIYNHTLSEMADL
EGISK-LTGVCPQS--NVQFGFLTVKE-NLRLFAKIKGIQPREVE-QEIQQVLRDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGSDPLSRHHVWNLLKER---
---------------KSNRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LAGDFLFKSCPS
LKVFSE--YFLLNKHPLFWNL---GSTI--FLHLN-E----------------------M
CDPDSI-TSLVKQH--------------------VPDAKL----RAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DDEIW-GEL-QSNRT--------KDTGSLVELE----QVLSSFK--
----ETKKS-I-----------------------RGMALWRQQLSAVAKV---------R
FLKLKNE-KKTLLTILLLLGISFCPQLLEHLFYELYQK-SYSWGLTPDMYFLSPGQPP--
QAPLTHLLVI-----NK--TGS-SIDNFIHSLRQQNIALEVDAFG----TRSG-PNEPSY
N-GAITVSGDG-EDYR---FSIACNTKRLNCFP-VV-MDIISNGLLGIFN----------
----------SSER--IQTDRSTYFEEHVS-------Y-EHGYL-----SNSFFWIPVAA
CFTPYIAMSSIGDYKRKA-YSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYVFSPDEI-----IYIIQNLL-VQILCSIGYASSLVFLTYVIS
FIFRNRRKNSGIWSFFFFII-----TIFTIVATDI---NEYEF-LGLFLCTILIPPF---
--SLI--------GSLFIFSEIS----------PDS------VDYLGASEHQIVFLALLI
PYLHFCIFVFVLWCLE-VNFRKKSMRKDPVF-RISPRSSGIFPNPEEPEG----EDEDVQ
IERRRTTNART-IADFESLQKPVIIASCLRKEYTGKKKDCFTKRK--KKVAIRNVSFCVK
KGEVIGLLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTIKMITGDTNPTAGQVI-LK--GSSE-------GD----SLGF
LGYCPQENVLWPNLSVREHLEVFAAIKGLEKGDAT-----VSIIW----LADALKLQDQL
KQPVKALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QLQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLELKVKNPAQVEPL
HCEILRLFPQAA--RQERYSSL--MVYKL-------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSFDAP00000007878 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKRKISLCQQTWALFCKNLIKKKR-----MKR
DTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
MEWLYS-AFLLFILY--TFY---TLHEVYDFSSMPPL--DLGRIDS--LNDS-TFVV
AYTPFNR------TTQRIMNKVSSASFM----------------------------M--G
RK--AIAFPDEENMTELISTQ-----YEDVVKVIFTSPF-SY----HLKFLRGSRIPIM-
---QE----HKDHTA----------------HCRKV---R-DSFDC-------GISQF--
WTEGFVALQAGINAAIIEIATNHSVMEELMSLTGKHMKIDSF---------IGHTGMM--
TDFFIFICIICFSPFTYYVSLSV-----------TKERKKMKGLMTMMGLRGPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLLY-AGFVFILTIFLAL----------ITKSVQFVILTSFLVVFSLFFFYG
LSLITLAFLLSV----------------------------LLKKPFLT---GFAV-----
FL-FTVIWGS--------LGFMALYRYLPGSLEWILSFFSPFAFTLGMAQLLHFEFD---
------MNSNT--ESMGDSNLIAATIFMLFLDSLSYLALTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRHSP
LFCLKSSFWHQQRTA-DHVA--LEDETESE-F-SDEAFEPVSTEFHGKEAIRIRDLTKEY
-------------RGK------P-----------------------------KNIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLAFDIYEGQITAVLGHSGAGKSTLLNVLTGLCVPTK--GWVTIHNNKLSEITDL
ENISK-LTGVCPQS--NVQFDFLTVKE-NLRLFAKIKGIQPNEVD-NEVQRVLQEMEMKN
IQDTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPFSRHRVWNFLKER---
---------------KAGHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKLFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------ISEAKL----SAESEGKLIYT--LPL
ER--TNKFPDLYRDLESCPDL---------GIENY--GVSMT----TLNEVFLKLEGE-S
GIGQP---------DIGAL-EDV-RAEGT--------RDTGRLSEME----DVVSSLS--
----GLRKE-K-----------------------VGLALLWQQVCAVAKV---------R
FLKIKHE-RKALFTLVAILGCGLLHILAANAHKIFYPE-DYCWELSPHMYFLTPDQQP--
RDPLSNLLII-----NK--TGE-SIDDFVRSLEKQNIALEVDAFG----SRND-TEELSY
N-GAITVSGSR-KNYS---FSLACNAKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2705)
-VL-VDIVSNGLLGILT----------
----------PSES--IHTDRSTYPGVDD---IY-SQV---NNL-----AYLTSWIILMS
SISPYISMTSIDDYKNKA-QFQLWISG-LNPSAYWFGQ-ALVEVPIY-------------
---FSLILFMYL---VYCTSKVKED-----IYTAVDVL-IQILYIVGYSISIIFMTYVIS
FIFRNGRKNSGIWSFCFYFI-----TLVPAV-I-M---DFLGD-VFLYCVSVLIPTT---
--AL
ENSGT00760000118965_1_Linker_4_5 (2705, 2873)
T--------GCTVLHFEHR----------V-----YHDII-LSKQGKKYEFLVYLV
PYVHFIIFLVILRCLE-CKLGKKTMRKDPVF-RISPRSSTVLHNPEDPEG----EDEDVQ
LERVRTANALT-SPNFE--QKPAIIASCLRKEYTEKK-CLFFKKK--KKTAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIRMITGETKPSAGQVL-LR--GSSA-------SE----PPGF
LGYCPQENVLWPSLTVGEHLQVFAAVKGLRKGDAE-----VAIAR----LVEALKLQDQL
QAPVRTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQIWKAIRAT
FRNSERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVRTPAHVEPL
HTEILRLFSQAA--RQERYSSL--MVYKLPVEDVQPLSQAFFKLETVKQSFDVE---EYS
L-SQSTLEQVFLELSKE--QELDD------------------------------------
--------FE-EELDP-SVKWKLLPQDEP----------------------
ENSPCOP00000004375 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKREISVCQQTWALICKNFLKKWR-----MKR
EPLMEWISS-LFLLLFLY--LYP---HGHDVHDFSSLPTL--DLGRVDS--FSES-RFSI
AYTPITN------TTQQVMDKVASASFL----------------------------VGKF
SS--NLGG--------------------------------------------------I-
---TV----SFLHKG----------------HCYEM---N-EDVNC-------EVSLF--
WEKGFVALQAAINAAIIEVTTNHSVMEELMSVTGRCMKIHPF---------IAQAGVI--
PF12698 // ENSGT00760000118965_1_Domain_0 (841, 1385)

TDMLIFFCIISFSPFTYYASVNV-----------TRERKRMKGLMVMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWISWGLLY-ASFIFLMALFLAL----------VIKSTQFIILTGFMVVFALFLLYG
LSLL
ENSGT00760000118965_1_Linker_0_3 (1385, 1687)
HNVILFVV----------------------------LIA-----------------
--------------------------FIPSS-----------------------------
------------------------------------------------------------
-------------------------------------LPP--------------------
--------------SS------P-----------------------------SFPLFF--
--L--D
PF00005 // ENSGT00760000118965_1_Domain_3 (1687, 1840)
LVLDIYEGQITAILGHSGAGKSTLLNILNGLSVPTK--GSVAIYNNKLSEMGNL
ENISM-LTGVCPQA--NVQFDFLTVKE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVRAQNLSGGQKR-KLTFGIAILGDPKI--FLLDEPTAGLDPFSRHRVWNLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LAGNCWFPLSNL
MRILRD--LRS-----IDGFL---NSRI--FLQLN-E----------------------I
CVQENI-TSLVKQH--------------------IPDAQL----STASEGKVVYT--LPL
ER--TNKFPGNGSPFSPFSPF---------N-------------------KWSKTSGL-S
TIL---------------------------------------------------------
----------------------------------NSPMMWLFLFFLISDY---------Y
GYITVVY-LYRVHVMLLMLVVGLSPLLVGNIMVKIYQN-SYTWRLSPHSYFLAPGQQP--
RDSLTQLLII-----NK--TGA-SIDDFIHSLELQNIALKVDVFG----IKNG-TDDPVY
N-GAITVSGNK-KNYN---FSFACNTKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSAH--IQTDRSTTG-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------V-----TVVSVAGF-MA--DTLER-GLQFYITFLVPPA---
--TLI--------GCFFLYLYSF----------AV------ALFTGE-SMGVTPFLIFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPQG----EDEDVQ
MERVRTANALS-STDFD--EKPVIIASCLRKEYAGKRKCCLSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
QGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSGG-------GD----TLGF
LGYCPQENALWPSLTVREHLEVYAAVKGLRKVDTE-----VTITR----LVNMLKLQDQL
KAPTKTLSEGMK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQQLKSK-FGKDYLLEMKVKTPTQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFG-EEIDP-SVKWKLLPQEKP----------------------
ENSANAP00000002106 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTGALLCKNFLKKWR-----VKR
ESLLEWMNA-LVLLLCLY--TYP---HGHQVNDFSSLLTN--DLGRLDA--FNES-
PF12698 // ENSGT00760000118965_1_Domain_0 (597, 1541)
GFSV
AYTPVTK------TTQQIMNKVASASFL----------------------------A--G
KM--VLGLPDEESIKEFTANH-----SEDIVRVIFTSTY-SY----HLKFLLGPRIPTK-
---KE----HKDHTA----------------HCYET---Y-EDVYC-------EVSEF--
WKEGFVVLQATINAAIIEITANHSVMEELMSVTGKIMKIHSF---------IGQSGII--
TDLFLFACIISFSPFIYYASVNV-----------ARERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLSF----------VIKSIQFIILSGFMVVFSLFLLYG
LSLVPLAFLMSI----------------------------LVKKSFLS---GLVG-----
FL-LTVFCGS--------LGFTSLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPSDGSHLIVATNFMLAFDTCLYLALV
ENSGT00760000118965_1_Linker_0_3 (1541, 1682)
IYFDKILPNE---YGRRRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDSDPS-SNDSFEPVPPEFHGKEAIRIR-----S
VTKE--------YKGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLIFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADQ
ENLCK-LTGVCPQS--NVQFDFLTVKE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPPI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2471)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCVGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIATL-GEV-QVEKA--------GDTEKLVELE----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQLCAIARV---------R
LLKLKHE-RKALLVLLLILIVGFCPFLVEYIMMKMYQN-SYTLELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSLEHQKIALEVDAFG----TRNG-TDDPSY
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDVVSNGLLGMVK----------
----------
PF12698 // ENSGT00760000118965_1_Domain_4 (2471, 2771)
PSVH--IHTERGTFLGNGQ-----SYPL---GFL-----VFIVFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LFPSAYWFGQ-ALVDVPLY-------------
---FLMFVFIYL---MSYVLEFEEI-----FL-TVIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TLFSVAGF-TF--SIFEI-EIPFLFTFLVPPS---
--TMV--------GCLFLSYHLF----------LS------PSFGGE-PKNVQAVLVFLI
PFLHFIIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-WKFGKKSMRKDPFF-RIYPRSSVVCQNPEEPEG----EDEDVQ
MERVRTANALS-STNFD--EKPVIIASCLRKEYAGKRKGCFSRRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSAG-------GD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRREDAE-----VAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNVAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQTFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGNFE-EDFDP-SVKWKLLPQEES----------------------
ENSMLUP00000007653 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHISVGQQTWALLCKNFLKKWR-----MKR
ETFLEWFFS-FLLVLFAY-LFSS---TIHYTDNFPQVPAI--YLGRVDH--FNDS-NYVI
AFAPESK------TTQEIMSKVASAPFM------------------------------KG
RT--ITGWPDEESMNALDLNY-----SIDAVRVIFDDNF-SY----HLKFVWGGRIPRR-
---KE----YRDHLA----------------HCQTS---N-EKVAC-------EGSLF--
WKKGFIAFQAAINAAIIEITTNHSVMEELMSVTGLNMKILPF---------VAQAGVG--
TDIFIFFCIISFSTFIYYVSVNV-----------AKERQYIKSLMTMMGLRELA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSVMY-AGFIFIMAILMAL----------VVKSTRVVVLTSFVVVFMLILLYG
LSLITLAFMMSV----------------------------LIKKPFLT---GFVV-----
FL-LTVVWGS--------LGFTALYRHLPAFLEWTLCLLSPFAFTAGMSQLIHLDYD---
------VNANTHLDSSSNPNLIIATCFMLVFDTFLYLALTLYFDKVLPTE---HGRRHSP
WFFLKPSFWFQHQRA-VHVA--LENEIDSDSS-SNDSFEPVSPEFHGKEAIRIKNLKKEY
------------KKGK------H-----------------------------EKVEAL--
--K--GLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNILSGLSDPTS--GSVTIYNHSLSETADL
ETVSM-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGIQPQEVE-REVQQVLQDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQI--LLLDEPTAGSDPLSRHRVWNLLKER---
---------------KSNRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDNI-TSLVKQH--------------------IPDAKL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRWSHQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DIGIW-TQL-QSDRT--------RDTGGLVELE----QVLSSFN--
----ETKEA-A-----------------------SGMALWRQQTCAIAKV---------R
FLKLKNE-KKTIMTILLLLCISLFPQLLEYLLYEIYRK-SYSWGLSPNMYFLSPGQPP--
QAPLTHLLVI-----NK--TGS-SIENFIHSLRQQNIALEVDAFG----IRRG-ANEPSY
N-GAITVLGDD-KHQR---FSIACNTKRLNCFP-VL-MDIISNGLLGVFN----------
----------SSEH--IQTDRSTYFEESMS-------E-EYEST-----SNPFFWIPGSA
CFTPFIAMSSIGDYKKKA-HSQLRISG-LHPSAYWFGQ-ALVDVPLY-------------
---FLILLVLQI---MDYIFNPDEM-----IVIIQNLL-IQILCSIGYVMSLIFLTYVIS
FIFRNGRKNSGLWSFFFLIV-----TIFLIVFTEM---TNYGF-LGLLICTILIPPF---
--TLI--------GSLLIFSEAS----------PDL------VEYIGASEEYLLYLTLLI
PYLQSFIFLFILRCLE-TNFRKKLMRKDPIF-RISPRSSKFFPNPEEPEG----EDEDVQ
MERMRTANAVT-IPDSD--EKPVIIASCLRKEYVGKKKNCFAKKK--KKVATRNVSFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVIGLLGHNGAGKSTTIKMITGDSTPTAGEVI-LK--RNSG-------GD----TLKF
LGYCPQENALWPNLTVREHLDVFAAVKGLRKADAA-----VAITR----LMEALKLQEEQ
KRPVKALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPAG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSR-FGKDYLLEMKVKTLAHVEPL
HSEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELEDFD-EEVDL-SVRWKLLQQEEP----------------------
ENSDORP00000006654 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------IKQRSLYQQTRALLHKNLLMKWR-----MKI
NSLLE
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
YGIP-VLLGVYMS--TIA---HFTYNMHFSGKPPE--NLGRLDQ--FNSS-SMTV
VYMPISN------TTQKIMNRIALSPFM------------------------------KG
KC--TQGKK-------ELLLH-----LPYSLGIIFNDIF-SY----NLKVV-DYSVPM--
---VE-----KSLSG----------------YCFES---YD-DFLC-------ESSLY--
WKGGFVALQTLINAVIIEMTTNHSVMEELMSVTAINMRALPS---------VSKHSFQ--
NEVFILFCLFYFISIIYFLSLNV-----------TRERKKYKDLMKIMGLYDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFIFSIFITV----------IITTTQTIVMTGFIVIFTLFFLYG
LSLIALSFLMSV----------------------------LLQKAALT---NFMM-----
FL-ITLFWGC--------VGFTALYKQLPSSLEWILSVCSPFAFTSGMSQIIHQDYN---
------FNGINFFDPSGESYVMIAKCSILVFDGVVYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKLLPYG---SELHHSP
LFFLNSSFCFQHWRT-KNNV--LEENLDPEQP-SDDYFEPVAPELQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYESQITAILGHKGAGKSSLLNIFTGLSVPTE--GSVTIYNKNPSEIQDL
EEIRK-RTGVCLQH--NVQFDILTLKE-NLRLFAIIKGIHPQEVE-REVQQILLEFDMQT
IQDDRVENLSEGQKR-KLTFGTAILGDPQI--LILDEPTVGLDPFSRQQVWSFLKEH---
---------------RANRVILFSTKYVDEAD----------------------------
--------------------S---------------------------LADRKVIMSHGK
LKCAGS--SIFLK---RKWGI---GYHL--SLHRN-E----------------------I
YDPEKI-TSFIKHH--------------------IPEAEL--K-TENKE-KLVYT--LPL
ER--TSRFPDLLSDLDAYSGQ---------GIMSC--DISIS----TLNEVFMDLDRK-S
ITEKDFEH--------------S-EM--L--------RASEGINETE----QACPSLL--
----QMRK-AV-----------------------SDLHLWRTQVCAIAWL---------R
FLKLKRE-RKSLLALLLILAIPFFFLIVELILLAV--QNNQNWEFKTGLYFLSPGQVP--
QDLCTSLLLL-----T--------------------------------------------
----IFVLVCI-KDYR---FSVVCNTKRLHCFP-VL-MNIISNGLLHMFN----------
----------HTQY--IQIKRNLFTFVIPF------ILQADIIIWFGFEDF-SFLFSVVA
NISPYIAMSSATDYKK-KADVQLWISG-LYHSAYWFGQ-AVTDVTLF-------------
---NFIIMLTYV---IVYVTKLKGS------SITSRMVFATVAYSFGYSTSLISLT----
---------------------------YVISFTFCKR-KKNSS-LWSLCFCIVSPHI---
--CIEDGDFKLSASFRCFQRSY-----------YY----SRELPEVVFDIRGTDLLICLI
PFFQTLVFIFVLRWME-LKYGKKVIRKDPIF-RIAPQSRDVHPNPEEIV----DEDEDVQ
AERTRTSTALT-VSNLN--EKPIIIASSLHKEYAVQKKRCFTKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3020)
RNISFCVN
KGEILGLLGPSGAGKSSSIRMIAGITKPTAGEVE-LK--GFRSVTG-DQGNN----TVSF
LGYCPQENVLWPLLTTKEHLEVYAAVKGLQKGEAA-----IAISR----LVNGFRLHDQL
NVPVQKLTTGAA---RKVCVLLDTCLKAGLRNAPEANRG----IS-VH-YSCVLQAIQTA
VKNTEQCILLTTHNLTEAEALCDRVAIMVSGKL---------------------------
---------------------------RCIGTIPHLKRK-FELLTVEREGYKG-------
----------------------------SPLN-GIHLLQMGHNKELLKQNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELESIE-E--DK-TMRWKHLSHSDEP---------------------
ENSCJAP00000000328 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTGALLCKNFLKKWR-----MKR
ESLLEWMNA-LVLLLCLY--TYP---HGHQVNDFSSPLTN--DLGRLDA--F
PF12698 // ENSGT00760000118965_1_Domain_0 (593, 1541)
NES-EFSV
AYTPVTK------TTQQIMNKVASASFL----------------------------A--G
KM--VFGLPDEESIKEFTANH-----SEDIARVIFTNTY-SY----NLKFLLGSRMPTK-
---KE----HGDHKA----------------HCYVT---Y-EDVYC-------EVSEF--
WNKGFVVLQATINAAIIEITANHSVMEELMSVTGKIMKIHSF---------IHQSGII--
TDIFLFACIISFSPFIYYASVNV-----------ARERKRMKGLMTMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSIQFIILSGFMVVFSLFLLYG
LSLIPLAFLMSI----------------------------WVKKSFLS---GLVG-----
FL-LTVFCGS--------LGFISLYRHLPASLDWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALV
ENSGT00760000118965_1_Linker_0_3 (1541, 1682)
IYFDKILPNE---YGRRRSP
LFFLKSSFWSQTQKS-DHVA--LEDEMDSDPS-SNDSFEPVPPEFHGKEAIRIR-----S
VTKE--------YKGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLIFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENLCK-LTGVCPQF--NVQFDFLTVKE-NLRLFAKIKGILPQEVD-EEIQRVLLEFEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPPI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2399)
AGLDPFSRHQVWNLLKER---
---------------KTDHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCVGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINEL---------DIATL-GEV-QVEKA--------GDTEKLVELE----QVLSSLN--
----KMRKT-I-----------------------GGVSLWRQQLCTIARV---------R
LLKLKHE-RKALLALLLILIVGFCPFLVDYIDIKMYYD-SYTLELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSLEHQKIALEVDAFG----TRNG-TDDP
PF12698 // ENSGT00760000118965_1_Domain_4 (2399, 2744)
SY
N-GAITVCGNE-KNYS---FSLACNAKRLNCFP-VL-MDVVSNGLLGMVK----------
----------PSVR--IHTERGTFLGNGQ-----SSPL---GYL-----MYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RAQLRISG-LFPSAYWFGQ-ALVDVPLY-------------
---FLMFTFISL---MSYVLVFEEI-----FV-TVIQI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TLFSVAVF-AF--SIFEN-EIPFLFTFLIPPS---
--TMV--------GCLFLSYHLF----------LS------SY
ENSGT00760000118965_1_Linker_4_5 (2744, 2873)
FGGE-PKNVQGVLVFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDPVF-RIYPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYAGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSAG-------GD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKEDAE-----VAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQTIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNVAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQTFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGNFE-EDFDP-SVKWKLLPQEES----------------------
ENSPEMP00000008864 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHFGVGQQMWALLCKNWLKKCR-----MRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLMEWFFS-FLLILLAY-RLSS---NLHQVHDAPQIPEM--DLGRVDS--FNDS-NYMI
AFAPESE------TIYKIMYKVASSPFM------------------------------KG
RR--IVACPDEKCMNELDLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPQV-
---KE----HKDHSA----------------PCETV---N-NKITC-------KNSIF--
WEKGFVAFQAAINAGIIEITTNHSVMEELMSVIGSNMKILPF---------IGQGGVT--
TDFLIFFCVISFSSFIYYLSINI-----------TQERQYITALMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILVVATLMSL----------IVKSAQVVVLTGFMVVFLLFLLYG
LSLITLAFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTIFWGS--------LGFTALYKHLPAFMEWSLCFLSPFAFTTGMAQLIHLDYD---
------VNSHVNLDSPNNSYLIIAILFMLVLDAFLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKILLSK---NGHQRSP
LFFLKSSYWLQHRGA-NHVV--LENEIDSEPS-LDDSFEPVPPEFQGKEAIRIKNLKKEY
------------T-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1839)
-GLGFDIYEGQITALLGHSGAGKTTLINTLCGLSPPTT--GSVTIYNQTLSEMDDL
DAVTK-LTGVCPQS--NIQFGFLTVRE-NLRLFAKIKGILPHEVE-QETKKLLYSIHLGK
ND-------------------SVALSTVQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2406)
TAGLDPLSRHRIWNLLKER---
---------------KLDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISSGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-D----------------------I
CEPESI-TSLVKKH--------------------IPDARL----TAQSEERLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
MVDES---------DVGIC-GHL-QSGGA--------KDMGSLVELE----RVVSSLE--
----SSGNT-I-----------------------SGMALWRQQLCAVAKV---------R
FLKLKNE-RKSLMTMLLLFGISFLPQLLEHLFYELYHE-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NR--TGS-RIDNFVHSLRQQNIALDIDVLG----TRNG-TEEALY
N-GAI
PF12698 // ENSGT00760000118965_1_Domain_4 (2406, 2769)
TVLGDG-KDLR---FSIACNTKRLNCFP-VL-MDIISNGLLGIFN----------
----------SSGR--IQTDRSTFFEEHMF-------Y-EHGYM-----SNAFFWIPLAA
SLTPYIAMSSINDHKKKI-LSQLWTSG-LYPSAYWCGQ-ALVDIPLY-------------
---FLILLLMQI---MDCVFSQEEI-----IFIIENLL-IQILCSIGYASSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----TIFCIVATDI---NEYGF-LALLFCTFLIPPF---
--TLI--------GSLLIFSEVS----------YDS------VDYLGASESQVLFLALLI
PYFHFLLF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
FFVLRCLE-RYLRKKSLRMDPVF-RISPRSCNAFPNPEEPGE----EDEDVQ
MERMRTAGAVT-ALQME--ERPVIIASCLRKEYTSKKKKCFSKAK--KKVAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTTISMITGDTKPTAGKVF-LK--GCGE-------GA----ALGF
LGYCPQENVLWPVLTVKEHLELYAAVKGLKKKDAL-----DTITR----LVDALNLQDQL
KAPVKTLSEGVK---RKLCFGLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAQVEPI
NTEIMRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDS-SVKWKLLPQEEL----------------------
ENSECAP00000017480 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKREISVCQQTWALLCKNFLKKWR-----MKR
EPLLEWLNS-FLLLLCLY--LYP---NNHQLNDFSSLPTM--DLGRVDS--FNES-KFAI
AYTPVTN------TTQQIMNKVASASFM----------------------------K--D
RE--VLGLPDEESIKELTANY-----PEEIVRVIFTNTF-SY----HLKFLLGHRIPTK-
---KE----HRDHTA----------------HCYET---I-EDIDC-------EVSEF--
WKKGFVALQAAINAAIIEITTNHSVMEKLMSVTGKNMKIYPF---------VSQGGVF--
TDFFVFFCIISFSPFTYYASVNV-----------TRERKRMKRMMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-ASFIFIMAFFLTL----------VIKSVQFVILTGVMVVFTLFLLYG
LSLIALAFLMSV----------------------------LIKKSFLT---GLVV-----
FL-LTVFWGS--------LGFMALYRNLPASLEWMLSLFSPFAFTLGMSQLLHLDYD---
------LNSNAFPDPSDLSNLIIATNFMLAVDIFLYLALTMYFDKILPNE---YGHRYSP
LFFLKSSFWSRQQKV-DHVA--LEDEIDSDPS-SNDSFEPMPPEFHGKEAIRIRNVTKEY
-------------KRK------S-----------------------------D
PF03193 // ENSGT00760000118965_1_Domain_2 (1674, 1719)
KIEAL--
--K--DLVLDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNRHSEMADLENISK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGIQPRELN-KEIQRVLLELEMQNIQNILAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKER------------------KTDRVILFSTQFMDEAD------------------------------------------------I---------------------------LADRKVFLSRGKLKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------ICIQENI-TSLVKQH--------------------IPDAKL----SAESEGKLVYT--LPLER--TNKFPELCQHLDSCLGL---------GIENY--GVSMT----TLNEVFLKLEGK-STIDES---------DIAVL-GEV-QAERA--------GDTERLVEME----QVLSSLN------ELRTT-L-----------------------EGMALWRQQICTIARV---------RLLKLKHE-RKALLSLLLILGVGFCPLLLEYIVMKIYQN-SYTWELSPHLYFLAPGQQP--HAPLSQLLII-----NK--TGA-SIDDFIHPVEHQNIALEVDTFG----TRNG-TDDPSYN-GAITVSGNE-KNYS---FSLACNTKRLNCFP-VL-MDIVSNALLGMVN--------------------PSAH--IQTDRSTFWEDDQ-----VNPL---EFL-----GHTIFWLVLSSCCAPYIAMSSIDDYKSKA-WSQLRISG-LFPSAYWFGQ-ALVDVPMY----------------CLFFLFMYL---MDYALNLQET-----IFKFVNRI-IQIPCAVGYATSLIFLTYVISFIFRKGRKNSGIWSFCFYII-----TVFSVAGL-LL--DNYGH-VALYSITFLIPQA-----TLI--------GCVFLSFHLF----------VL------SFFSEE-PRGVEPFLVFLIPFLHFIIFLLILRCLE-WKFGKKTMREDPFF-RISPRSSKVHQNPEEPEG----EDEDVQMERERTANALT-STNFD--EKPVILASCLRKEYAGKRKRCFSKSK--KKIATKNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSSG-------GD----ALGFLGYCPQENALWPNLTVKEHLEVFAAVKGLRRRDAA-----VAITG----LVDALKLQDQLKLPAKALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL------------------------------------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPEQGETLHSEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFLKLEMVKQSFHLE---DYSL-SQSTLEQV----------------------------------------------FLELSKDQELEDFD-EQLPR-SVKWKLLMQEEA-----------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSVPTK--GSVTIYNNRHSEMADL
ENISK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGIQPRELN-KEIQRVLLELEMQN
IQNILAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSRGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CIQENI-TSLVKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TNKFPELCQHLDSCLGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TIDES---------DIAVL-GEV-QAERA--------GDTERLVEME----QVLSSLN--
----ELRTT-L-----------------------EGMALWRQQICTIARV---------R
LLKLKHE-RKALLSLLLILGVGFCPLLLEYIVMKIYQN-SYTWELSPHLYFLAPGQQP--
HAPLSQLLII-----NK--TGA-SIDDFIHPVEHQNIALEVDTFG----TRNG-TDDPSY
N-GAITVSGNE-KNYS---FSLACNTKRLNCFP-VL-MDIVSNALLGMVN----------
----------PSAH--IQTDRSTFWEDDQ-----VNPL---EFL-----GHTIFWLVLSS
CCAPYIAMSSIDDYKSKA-WSQLRISG-LFPSAYWFGQ-ALVDVPMY-------------
---CLFFLFMYL---MDYALNLQET-----IFKFVNRI-IQIPCAVGYATSLIFLTYVIS
FIFRKGRKNSGIWSFCFYII-----TVFSVAGL-LL--DNYGH-VALYSITFLIPQA---
--TLI--------GCVFLSFHLF----------VL------SFFSEE-PRGVEPFLVFLI
PFLHFIIFLLILRCLE-WKFGKKTMREDPFF-RISPRSSKVHQNPEEPEG----EDEDVQ
MERERTANALT-STNFD--EKPVILASCLRKEYAGKRKRCFSKSK--KKIATKNVSFCVR
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIKVITGDTKPTAGQVL-LK--GSSG-------GD----ALGF
LGYCPQENALWPNLTVKEHLEVFAAVKGLRRRDAA-----VAITG----LVDALKLQDQL
KLPAKALSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPEQGETL
HSEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFLKLEMVKQSFHLE---DYS
L-SQSTLEQV----------------------------------------------FLEL
SKDQELEDFD-EQLPR-SVKWKLLMQEEA----------------------
ENSCANP00000025809 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRCMSVGQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMKKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAT---N-EKMRC-------EGSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYISVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNALLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YRHRCSP
LFFLKSCFWFQHGRA-NHVV--LENETDSDPT-PDDSFEPASPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSGMADI
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2396)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDEA--------KDIGNLVELE----QVLSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQPP--
QDPLTHLLII-----NK--TGS-SIDNFLHSLRQQNIAIEVDAFG----TRNG-T
PF12698 // ENSGT00760000118965_1_Domain_4 (2396, 2771)
DDPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHTD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTVLLPPF---
--TLI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
TERMRTANAMG-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GD----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--GQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFNP-SVKWKLLPQEEP----------------------
ENSPCAP00000009865 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNQKKKHLLQQTQALLXXXXXXXXX-----XXX
XXXXEWVFP-IVIGLFMG--LFH---I-REGTHVPETPSQ--DLGRVDA--FNSS-DMMV
VYTPVSN------VTQQIMNKTASAPFL------------------------------QG
RT--VIGAPDKKSMDAIILDN-----APYIVAIVFNDNF-SY----KLMFFQDYFIPYM-
---KD-----EYFSA----------------YCWKD---HH-GTSC-------SLSLY--
WKRGFVTLQTAIDAAIIEITTNHSVMGELMSVTGMNMKILPF---------LSKYRLQ--
NEISILYCLIYFSSFIYFVSLNV-----------TKERKKLKDLKMMG-LQDAA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-GGFIFFTSLLITI----------VVTSARIILMTGFMVMFTLFFLYG
LSLMTLVFLMSV----------------------------LLKRSSLT---SLVV-----
FL-FKFFWGC--------LGFMALYKQLPSSLEWILSICSPFAFTSGLSQIIHLDYK---
------LTDSTFPDPSGDSYVLIGTFSILAFDGLLYLVLALYSDRILPYG---NERHYSP
LFFLKSLPCFRHQRT-DYEV--VEKEIDPDHS-ADDCFEPITPEFQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------EKVEAL--
--K--GLFFDVYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGPSGAGKSSLLNILNGLSVPAE--GSVTIYNRNLSEMHDL
EEIRK-ITGMCPQF--NIQVDILTVKE-NLRLFAKIKGIQPQEVE-REVQRILLELDMQN
VQDNLAKNLTQGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHRVWNFLKEI---
---------------KRDHVILLSTSFTDEAD----------------------------
--------------------V---------------------------LADRKVIMANGR
LKCAGS--SLFLK---RKWGV---GYHL--SLYRN-E----------------------T
CDPERL-TCFVNHH--------------------IPEAKL--K-TESKD-KLVYT--LPL
ER--TSAFPDLFSDLDKCSGD---------GLVSY--DISRS----SLSEVLVKLEGK-S
TSQQDFEL--------------A-EV--K--------GGPGRQDKME----PACFSLP--
----ETPK-AM-----------------------SSMALWRLQLCAIARL---------R
FLKLRHE-RKELLTLLLMFGIAMLPLLVEMLFYAMLSQ-NADLELKPELYFLAPGDLP--
REDHTSLLII-----NNTES---NIEDFIHALKRQNILLEVDDFE----NRNG-TDDLSY
S-GAIIVSGKQ-KGLL---CYKXXXXXXXXXXX-XX-XXXXXXXXXXXXX----------
----------XXXX--XXXXXXXXXX-------------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------
---XXXXXXXXX---XXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-----XTPVIVLDFVVL-YPLNI-AALITIMALFPSL---
--T--IP------GFWIFLQQX-----------XXXX--XXXXXXXXXXXXXXXXXXXXX
PYVQFMTFLFVLRCLE-AKYGKKTMQKDPVF-RISPQSRCARPNPEEPV----DEDEDVQ
TERRRAATALT-TSNID--EXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX
X
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
XEILGLLGPNGAGKSSSIRMLSGITKPTAGQVE-LK--GSSSVW-------------GH
LGYCPQEKTLWPNLTVKEHLDVYAAVKGLGNEDAK-----VAIAR----XXDAFKLQELL
HVPVQKLTAGAD---RTVCLVLSLLGNSPVLLLDEPFTG----LDPAG-QQRMRQAIQAA
IANSEKGAVLVTHRLAEAEALCDRVAIMVSGSL---------------------------
---------------------------RCIGLIEHLKSK-FGKDYVLELRMKEPSQVTLL
HNEILKLFPQAL--RQERYSSF--MVYKLPMADVQPLSQAFHKLETXXXXXXXX---XXX
X-XXXXXXXV----------------------------------------------FLEL
SIEQELEDFD-EDVNT-TMRWKLLSRSDDP---------------------
ENSSTOP00000020599 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRRISMGQQIWALLCKNCLKKWR-----MKR
ETSL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWLFS-FLLILFAY-LLSS---NLHQINDSPQKSAVDLNLGRVDK--FNDS-NYVI
AFAPESK------TTQEIMNKAASAPFM------------------------------KG
RT--IIGWPDENSMNELDLNY-----SVDVVRVIFNDMF-SY----HLKFSWGYRIPKM-
---RE----HKDHSA----------------HCQAI---A-KKITC-------ESSVF--
WEKGFVAFQAAINAAIIEVAVNHSVMDKLMSVTGLNMEILPF---------IAQGGIA--
TDFFIFFCIISFSSFIYYVSVNV-----------AQERQFIKSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-ASFILIMAILMAL----------IIKSAQVVILTGFVVVFILFLFYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLAI-----
FL-LIIFWGS--------LGFTALYRHLPAFLEWTFCLLSPFAFTAGMAQLIHLDYD---
------VNSNVHLDSSNSSYLIIATLFMLVFDALLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKILPNK---FGHSHSP
WFFLKSSFWFQHQGA-NHMV--LENETPSDPS-WDDSFEPVSPEFHGKEAIRINNLKKEF
------------T-GK------H-----------------------------EKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGLDIYEGQITALLGHSGAGKTTLLNILSGLSAPTS--GSVTIYNHTLSEMADF
ETVSK-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQRVLQALEMES
IQDILAQNISGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPLSRHRMWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISSGR
LKCAGS--SLFLK---KRWGI---GYQL--SLHLN-E----------------------M
CDPESI-TSLVKQH--------------------IPDAKL----TAQSEERLIYI--LPL
ET--TSKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
TVDES---------DIGNW-QQL-QGDGA--------KDRGNLVELE----QVLTSLY--
----ATKKT-A-----------------------SGMALWRQQVCAIAKV---------R
FLMLKKE-RKSLLTMLFLFGISFIPQLLEHLFYELYNK-SYSWGLSPNMYFLSPGQQP--
QDPLTLLLVI-----NK--TGS-SIDNFIHSLRRQDIALEVDAFG----TRNG-TNEPFY
N-GAITVLGDE-KDHR---FSIACNTKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2769)
-VL-MDIISNGLLGIFN----------
----------SSER--IQTDRSTFYEEQMP-------S-EYQYL-----SGAFFWLPVVA
CFIPYIAMSSIGDYKRKV-HSQLWISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLIMQI---MDYVFSSEEI-----IIIIQNLS-IQVLCSIGYVSSLVFLTYVIS
FIFRNGRKNSGLWSFFFLIV-----TVFTTVANDL---NEYAF-LGLLFSTILVPPF---
--TMI--------GSLLIYSEIS----------FDS------MDSSEASDSPVLFLALLI
PYLHCFIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFVLGCLE-RNFRRKSMRKDPVF-RISPRSGDVSPNPEDPEG----EDEDVK
IERTRTANAMA-ILDLP--QKPVIIASCLRKEYAGKKKNCFSRPK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTSGQVI-LK--GSCG-------GD----VPGF
LGYCPQENVLWPSLTVREHLEVYAAVKGLKKRDAS-----AIITQ----LVDAFKLQDQL
KGPVNTLSEGIK---RKLCFLLSILGNPSVVLLDEPSTG----MDPEG-QQHMWQAIRAT
FRNSERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAQMEAL
HAEILRLFPRAA--RQERYSSL--MVYKLPVEDVKPLAQAFFKLEKLKQSFHLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDVFD-DELDP-SVNWKLLPQEEP----------------------
ENSMICP00000015737 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MEKMALASFM------------------------------KG
RT--IVGTPDEETMDTILLQK-----YPEIVGVVFSDTF-SY----QLKFHWRYRIPSI-
---KE----HSEYSE----------------HCWTI---NGKY-FC-------YLEKY--
WKKGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQTAINAAIIEVTTNHSVMEKLTSVIGINMKILPF---------TSKGEVI--
NELFIFICVVCFSSFIYFASLNI-----------THERKKFKKLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-TGFIFIMSIFMVL----------IITSIPIIVHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIKKPLLA---GLAT-----
FL-FSVFLGC--------LGFTVLYRQLPLPLEWALGLLSPFAFAAGMAQITYLDYN---
------LNGVIFPDPSGDSYFMIATFFILAFDTLLYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFERVLPDK---DGHRQSP
LFFLKSSFWSKHK-NTHHEV--FQNEINPEHF-SDDSFEPVSPEFHEKEAIRIRNIKKEY
-------------NGK------P-----------------------------GKIEAL--
--Q-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GIFLDIYEGQITAILGHSGAGKSTLLNILSGLSISTE--GSATIYNTQLSELTDI
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRLFAKIKGIQPKEVE-QEVKRIIMELDMQN
IQDVIAEKLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHRVWNLLKER---
---------------KMDRVILVSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFLFNGK
LKCAGS--SLFLK---RKWGI---GYNL--SLHRN-G----------------------M
CDTERI-TSLIKQH--------------------IPDAKL----TAESEEKLVYS--LPL
ER--TNKFPDLYSDLDKCSDQ---------GIMNY--GVSMT----TLKEVFLNLEGK-S
TMDEP---------DFGIG-KQE-KINVT--------RDTGNESEVQ----QALCSFP--
----EMRKA-V-----------------------RNGTLWRRQVCAIARL---------R
FLKLRHE-KKTFLSLSLILGVAFIISIIENVMYGVGHH-TLRWGLSPSMYFLSLEQLP--
KPSLTSLLII-----NN--TGS-NIEDLVRSLKHQDIVLEIDDFS----NRNG-SDDPSY
N-GAIIVSGDQ-KDYS---FSVACNTKKMNCFP-VL-MGIVSNALLGLFN----------
----------FTDL--IQTEKNVFPHDDR-------------MLGNSIINGAILLLMVAN
CIFPYIGMSSTSDYKRKA-HFQLWISG-LCPSAYWCGQ-ALVDIPLY-------------
---CLILLLVDL---ISYFIFL----GF---KFPWKLTIVAVVCIVGCAASLIFLTYVLS
FIFCKGRKNKGFWSFGFFIV-----SIFILIIL-IS--TQYRN-LSLILCMILVPSY---
--TSI--------GFFMSLTDLH----------LT-LLYFEILDKGISEVKKTIFFTVLI
PYLQSIIFLFVLRHLE-MKYGNEIMREDPVF-RISPRSRETHPNPEEPGE----EDEDVQ
AERVKTANALT-APNLN--EKPVIMASCLHKEYKEKKKSCFSIRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNLSFCVK
KGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVV-LQ--DSRA-SVRRQEDH----SPKF
LGYCPQENSLWPNLTMKEHLELYAAVNGLGKEDAA-----LSISR----LVEALQLQEQL
KIPVKTLSEGVK---RKLCFALSILGNPSVVVLDEPSTG----MDPKG-QQQIWQAIKNI
IKNKERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEIKMKEPTQVEPL
HTEILKFFPQAA--RLERYSSL--MSYKLPVEDVHPLGQAFFKLESVKHSFDLE---EYS
L-SQATLEQI----------------------------------------------FLEL
SKEQELENFD-DEVDT-TVRWKLLSHEEP----------------------
ENSFALP00000002619 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MKTVQRNISVFQQTKILLWKNVLIKWR-----MKM
QSFQEWILS-LLFLPLVF--MVAS--LMHQ-SHYAEVPFT--LLGHLDDPAFNAT-GATV
TFTPATA------TTRHIMSRVASSSVM------------------------------KG
IN--LEEVEDERAMKKAWISN------EEIIGVVFKDNF-SY----HLRFPSSHMVI-P-
---NE----VVGDVD----------------SCHN----FS-WEYC-------ESPRY--
WYKGFLSLQSSIDAAIIEMVTNHSVWEEMKSIAGVRMKSQSI---------LFSISLE--
YSYFMVVIVMCFLPFMYFLSRHV-----------TREKKQLKVLMKTMGLQDIA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-SLYVLLFSCLLTA-----------LLLREPFYTSSFPAVSLLLFLYG
LACIHLVFMLSS----------------------------LLKTAKLV---SSMG-----
FL-IIFIFGF--------LSLAVLIEEVPEPLKWFLGLLCPFAFNTGIAKIFHLEKY---
------EIGFSFSNLMEEAHFLFSTYILLVFDSVLYMLLALYFDKILPGK---YGMPDPP
LFCLKASYWMRSRRG-STRD-VPRASANPEEQ-LGDDVEPVPPEFLGKEAIRIHNIKKAY
-------------KKK------D-----------------------------KKTEAL--
--R--GLSLTIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNVLSGLSFPSE--GSATIYNYKLSEMGDR
EEIRG-LVGICPQF--NSHFEVLTVRE-NLKTFAEIKGIKSKEVE-QEVENILELLDISN
IQDTQAEKLSGGQKR-KLSIGIAMLGNPQV--LLLDEPTAGLDPLSRHQVWSLLRER---
---------------RAGRAILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAFISHGR
LKCVGS--SLFLK---KKWGI---CYHL--RIHVS-E----------------------S
CDLENL-TSLVKGH--------------------IPNATF----SGHTQYELRYK--LPL
EN--VNKFPDLFSGLDSCSEQ---------GIINY--GVSLT----TLEDVFLRLEGE-A
TADPE-DP---------IP-GEE-WGAA---------A--GSPEEAR----PCSQLLA--
----DPSTALR-----------------------QELALWRQQSSAMARV---------H
FLQLKSS-VKNLRSILLLYAVFLLPLVLQLCVVAGWQS-VSAWQLSPERYFLPLGRRP-H
-LDATTLLVY-----NH--TGT-GIDDFIHVLQSQDLTVEMAKEE----N---ITEELQH
N-GAIKVSRKG-QSYR---FTVLCHLEAINCFP-VL-VNVISNTLLRTLN----------
----------STEH--IQVWSHPFFSL-----------FHRGYWDYFMSFYVIYMLLLFP
GFPPHFAMGYTQDCKA-GARAQLRISG-LFPSAYWCGQ-ALVDIPLC-------------
---WILLFSMFG---LQFAISNK-------VSGSASTFFLLVTGMLGYGISLVLLMYLIS
FNSRKGW-SCDLWSFILILV-----CFITFFIDRVVDHIDSSN-ITFYILSLLVPLY---
--PLM--------GFVFYC---------------L-HDSEMFSVPSDSHIPFAAFA----
PYIHSVVFILLLRFLE-LKYGKAVLRRDPIF-RISPRRESGQQPPKVLE----EEDEDVR
AEREAVRNAVV-APRHE--EKSVIIVNNLCKEYEIKQAGSFFKKK--KKAATKNLSFCVK
KGEVLGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STAIKMITGETALTAGQVL-MK--RGGGG---GSQEQ----APAF
LGYCPQENPLWLDLTPQQHNSQRKPCKEIRKLSCR-----SAFQR----IVIGLQLQDYL
NKKVRKLPAGIT---RKLCVALSMLGNPSVLLLDEPCTG----MDPNG-QRRVWKAIRDA
LKAKESGAILTTHYMEEAEAVCDRVAILVSGQL---------------------------
---------------------------RCIGSIQYLKNK-FGKGYLLEIKVKDAESTDVL
HAEILKIFPGAA--RQERFPCL--LVYKVPMKDALPLSQSFSKLEEAKQSCSLE---EYS
F-SLNTLTQV----------------------------------------------FLEL
SREQEKDNFD-LTLDG-TFDWKQLQQED-----------------------
ENSSSCP00000018283 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRIKQKSVYQQTQALLCKNFLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWGFP-ILLGLYMG--VFS---YIKENVRFPEMPPQ--DLGRVDK--FNSSSMD-V
VYTPISD------ITQQIMNKTAFAPFL------------------------------KG
RK--IIAVPDQKHMDKVLLDN-----FPFTVGVIFSDTF-SY----KLKFFQGYDIPIS-
---KE-----DLFTA----------------HCWGT---DD-EFSC-------SLTKY--
WSDGFVTLQTAINAAIIQITTDRHVMEELMSVTAINMKTLPF---------IFKENLQ--
NEMFIFYCLLYFSPFIYFLSLNV-----------TKERKKYKDLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGVIY-AGFIFIASIIITV----------IITSTQIIVMTGFMVIFTLFFLYG
LSLITLAFLMSV----------------------------MLKKSILT---SIAV-----
FL-LVLFWGC--------VGFTAFYRQLPSPLEWIFSICSPFAFTAGMTQIIRLDYN---
------MNGVVLPDASGESYIMIATFSILVFDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NERHYSP
LFFLKSSSCFQHQ-RIDDKV--IEKELDPDHP-SDDYFEPIAPEFQGKEAIRIRNVKKEY
-------------KEK------T-----------------------------GKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFFDIYEGQITAILGHSGAGKSSLLNILNGSSVPTE--GSVTIYNKNLSEVQDL
EEVRK-ITGVCPQF--NVQLDTLTVKE-NLRLFAHIKGIQPQEVE-QEVQRILLELDIQN
VQDSLATHLSEGQKR-KLTIGIAILGDPQV--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2301)
TVGLDPFSRHRVWSFLKKH---
---------------RADRVILFSTNFMDEAD----------------------------
--------------------V---------------------------LADRKVILSSGR
LKCAGS--SIFLK---RRWGL---GYHL--SLYRN-E----------------------I
CDPDKI-TSFINRH--------------------IPDAKL----KTESKEKLVYT--LPV
ER--TTKFPDLFSDLDKGSGL---------GVMSY--DVSTS----TLNEVFLQLEGK-S
ATEQD----------------LE-QAEI---------RDSGSLHEME----PACSSLP--
----EMQKT-V-----------------------SDMGLWRMQLCAVARL---------R
FLKLKRG-KKALSTLLLVFG
PF12698 // ENSGT00760000118965_1_Domain_4 (2301, 2696)
IAVFPLIVEGILYAVLNQ-KTDWEFKPELYFLSPGQPP--
QDPRTSLLII-----NN--TGS-NIEDFIQSVKHQNILLEIDDFE----NRNG-TDDPSY
N-GAIIVSGKR-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------YTQY--IRTESGSFPFNYA-------------LFWTGLPKGSFFLFFVMC
SISPYIAMSSVSDYKKRT-KSQLWISG-LFPSAYWCGQ-ALVDVSLY-------------
---DFILLSMYL---IFYLANL---VHV---YLTSRIVFALGVITFGYAASLVFLTYVIS
FIFRKRRTNSGLWSFCFYIV-----PVFTFGII-VI--DYLDL----IVCMVLFP
ENSGT00760000118965_1_Linker_4_5 (2696, 2873)
SM---
--TLG--------GFVALLETRI----------HKYQMNYGD---LNYDLNAADLLFCLI
PYFQALLFVFVLRCLE-TKCGKKIMHKDPVF-RIAPRSRDARPNPEEPVD----EDEDVQ
AERIRTATALT-TS-IE--EKPVVIASCLRKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEILGLLGPNGAGKSSSIRMISGVTKPTAGEVE-LT--GYGSG-LGHRRDG----RVQF
LGYCPQENVLWPVLTVREHLEVFAAVKGLRKADAS-----VAISR----LVDSFKLHEQL
NVPVQYLTAGAA---RKLCFVLSILGNPPVLLLDEPSTG----MDPAE-QQQVWQTIQTA
VKTAERGALLTTHYLAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSVQHLKNK-LGKDYVLELRVKETSQVTSV
HTEILKLFPQAA--QQERYSSF--LAYKLPVEDVHPLSQAFHKLEAVKRDFNLE---EYS
L-SQCTLEKV----------------------------------------------FVEL
SKEQELGSAD-EEVDT-TMRWKLLPYSEDP---------------------
ENSPSIP00000009610 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MQRFQRNTSVCQQTKALLCKNLLIKWR-----MKM
QTFQEWILS-LLFIFLIY--LIST--TTYY-PPDPEIPHA--FLGRLDDPAYNAT-GITV
AYTPVTS------RTRHIMKKVASESVM------------------------------MG
IT--IEEMADEKALEAAWILN------DEMIGVVFKDDF-TY----QLRFSPSNVIA-P-
---NE----HFGHID----------------SCYN----FS-EVYC-------NSPRY--
WYKGFLSLQSSIDAAIIEMTTNHSVWEEMKSISGVRMESPGI---------IPLVSLE--
YSFISFAIAICFTPFMHFLSSNL-----------TREKRKLKELMKMMGLQDAA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-MVYVLIMSSGLAA-----------ITISEFFYTSSYFLILLLFFFYG
VASIHFCFMLSA----------------------------LLKKPKLT---SSIG-----
FL-LTFFSAS--------LSLITLVERLPAPLEWALGLLCPFAFTTGISKILHLEKY---
------GVGFYFSNLMDESYAVFTAYILLIFDSVLYMLLALYFDKVLPDK---YDRKYHP
LFCFKPSYWCQSRRS-SVGE-RPEMEENHECI-FNDSMETVPPALDGKEAIRLNNIKKTY
-------------KTK------D-----------------------------KEIEAL--
--K--GLFLNIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLSQPSY--GSATIYKYKLSDLRDM
EEARA-LLGVCPQF--NVQFETLTLKE-NLRVFAEIKGIRATEVE-YEVQKVLKLLDIIN
IQDTQANKLSGGQKR-KLSLGIAILGDPQV--LLLDEPTAGLDPRSRHYVWNLLKER---
---------------RAGRVTLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAFISHGR
IKCVGS--SLFLK---KKWGI---GYHL--RMHVN-E----------------------G
CDSGSM-ISLIRQY--------------------IPEATF----TGQSENELSYA--LPL
EN--VDKFPDLFCELDNHSRQ---------GIVNY--GVSMT----TLEDVFLKLEGE-E
TVDQEDYG---------VF-SEE-QAEEE--------RDSFPADEME----QGLLSLS--
----DIGKATV-----------------------SGIALWRQQVCAVARI---------R
FLKLKHE-YKALRSILLLCGFFMIPIAIQFIMVGLWEH-LNSWELSPGLYFSP-GQQS-H
-KEVTSLLVL-----NN--TGS-SIQDFIHSLETQNIMLEIATGK----N---ITKRLIH
N-GAIQVSWEN-QSYR---FTVMCSIETINCFP-VL-VNIISNALLCTHN----------
----------STAH--IRIWNHPFFNS-----------HRPGMWNYFIMIYLMTAVFLVP
GFPPHLAMNSIQDYKL-KARSLLRISG-LFPSAYWCGQ-ALVDIPLY-------------
---LVLLCTIFG---IISTLSSR-------NWMAASGVFALFAGIISYGASMILFVYVIA
FVFRKRCNSCDFWSFILIVT-----ALVSTIISFITMVVISES-LSHYIFSILIPMY---
--PLI--------GVVIKSM------------KFFMEDEYFIDFGHWSDIFISIFS----
PYLHCAVFIFLLRWLE-MKYGKAVMREDPIF-RIPLRNEINHPNPEEPE---EEEDEDVQ
AERARVRGTIA-SENQQ--EKPIIIVNNLRKEYKDKKASSVFKKR--KKVATKNVSFCVK
KGEVFGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTINMIAGETALTAGQVL-VK--GKGAAEA-QLEES----TTGF
LGHCPQENPLWPNLTVQQHLEVYAAVKGMRKEDAM-----LTIRR----IAKALELQDHL
KKAIRKLSAGVT---RKVCFALSMLGKPTVLLLDEPSTG----LDPKG-QSHVWKAIRAA
LKNKQQGAILTTHHMEEAEALCDRVAIMVCGKL---------------------------
---------------------------RCIGAVQYLKSK-FGKGYLLEIKVKDPAQVDCL
HMEIMRIFPHAD--RQERVSAL--LVYKVPMHNALPLSQTFSKLETAKRTFGLE---EYS
F-SLNTLEQV----------------------------------------------FLEL
SREQEMNNFD-TALEG-TFEWKRLHQEDL----------------------
ENSMAUP00000003441 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRVGQQMWALFCKNWLKKCR-----MRR
ETAMEW
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
FFS-FLLIFLAY-RLSS---NLHQVHDAPQIPEM--DLGRVDN--FNDS-NYII
AFAPESK------TIYDIMSIVASTPFM------------------------------KG
RR--IVACPDEKSMDELDLNY-----SMDAVRIIFKDTF-SY----HLKFSWGHRIPPI-
---KE----HKDHSA----------------PCEIV---N-NKTTC-------RNSVF--
WEKGFVAFQAAINAGIIEITTNHSVMEELMSIIGSNMKILPF---------IAQGGVT--
TDFLIFFCVISFSSFIYYLSVNI-----------TQERQYITILMTTMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLMY-AGFIFVVATLMSL----------ILKSAQIVVLTGFMVVFLLFLLYG
LSLITLAFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTVFWGS--------LGFTALYKHLPAFMEWTLCFLSPFAFTAGMAQLIHLDYD---
------VNS-VNLNSPSNSYLIIATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKILLSK---YGHQHSP
LFFLKSSYWFQHRGA-NHVV--LENEIDSDPS-LNDSFEPVPPEFQGKEAIRIKNLKKEY
------------T-GK------H-----------------------------GKFEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINILCGLSPSTT--GSVTIYNQTLSEMDDF
DAVIK-LTGVCPQS--NIQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQRVLQELEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2381)
AGLDPFSRHRIWNLLKER---
---------------KLDRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------I
CDRESI-TSLVKKH--------------------IPDARL----TTQSEERLIYI--LPL
ER--TNKFPDLYRDLDRCSSQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
MTDES---------DVGIS-GHL-QSQGE--------KDVGSLVELE----RVLSSLD--
----SSGNT-V-----------------------SGMALWRQQLCAVAKI---------R
FLKLKNE-RKSLMTMLLLFGISFLPQLLEHLFYELYHE-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-SIDKFVNSLRQQNIALD
PF12698 // ENSGT00760000118965_1_Domain_4 (2381, 2768)
MDVLG----TRNG-IEEALY
N-GAITVLGDE-KDLR---FSIACNTKRLNCFP-VL-MDIISNGLLGIFN----------
----------SSER--IQTDRSTFFEEHMF-------Y-EHGYM-----SNAFFWIPLAA
SLTPYIAMSSISDYKKKI-LSQLWVSG-LYPSAYWCGQ-ALVDIPLY-------------
---FLILLLMQI---MDCVFSQEEI-----IFIIENLL-IQILCSIGYASSLVFLTYIIS
FIFRNGRKNSGIWSFFFLIV-----TIFSLVATDM---NEYGF-LGLLICSFLIPPF---
--TLI--------GSLLIFSEIS----------YDS------VDYVGASESQVIPLALLI
PYFHFLL
ENSGT00760000118965_1_Linker_4_5 (2768, 2873)
FFFVLRCLE-RYLRKKSLRMDPVF-RISPRSCNAFPNPEEPGE----EDEDVH
MERMRTAGAVA-ALQID--ERPVIIASCLRKEYTGKKKKCFSKAK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTTINMITGDTKPTAGQVL-LK--GCGE-------DA----ALGF
LGYCPQENVLWPILTVKEHLEVYAAVKGLKKKDAL-----VTITR----LVDALKLQDQL
KAPVKTLSEGVK---RKLCFTLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPAQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPVEDVQPLSQAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EEIDS-SVKWKLLPQEEL----------------------
MGP_PahariEiJ_P0037448 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVRQQTCALLQKNLLKTWR-----LRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1541)
TLMEWVSS-LLLLLFLY--WYP---HGHEATDLSSVPTK--DLGRVDS--FRQS-GFTI
GYTPVTS------MTQQIMEKVAAAPFM----------------------------A--G
KK--VLGLLDEENIKELTESH------AEIIRVIFSDTF-SY----HLKFQFGQRIPTS-
---RE----LKDHNA----------------HCDGL---Y-EDANC-------LIAIF--
WTEGFVALQAAINAAIIEITTNHSVMEELLSVSGKFIKIHPF---------VSQKGIL--
TDFFIFICIVSFSPIIYYLSINV-----------ARERKKMKSLMMMMGLRDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFIMALSLAL----------VIKSVQFFILTSFMMVFSLFLLYG
LSMIALAFLMSV----------------------------LVRKTVLT---GLSV-----
FL-LTIFWGS--------LGFTALYRYLPAPLEWTLSLFSPFAFTLGMAQLLRADYD---
------LHSNAPPDSAGGSSLIITTNFMLVFDAFLYLALM
ENSGT00760000118965_1_Linker_0_3 (1541, 1682)
MYFVKVLPNE---YGHQHSP
LFFLKSSFWLRTRKP-AHVI--LEDGIEPVPS-SDDSFEPVSPEFHGKESIRIRNISKEY
-------------TGK------S-----------------------------NKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPSK--GSVTIYNNKLSEMADL
ENILR-ISGVCPQS--NVQFDFLTVRE-NLRLFAKIRGIPPQDVE-KEVQRVLLELEMKN
IQDILAQNLSGGQKR-KLTFGIAILGDSQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2298)
AGLDPFSRHRVWNLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGV---GYHL--SLQLK-E----------------------A
CAPENI-TSLVKQH--------------------IPEAKL----SAEGEGKLLYT--LPL
ET--TYRFPELCQSLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-E
AIDEP---------EFDIV-GEG-QTERS--------GDTERLMEME----QALSSLM--
----ETKK--T-----------------------DGMALWRQQTCAIAKV---------R
LLKLKHE-RKTLLSVLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2298, 2745)
ILAVGICPLLFKNITTKIRQS-SYTWELSPHEYFLAPEQQP--
QGMLTQLLII-----NK--TEA-SIDDFIHSVERQNIALEVDASG----TRDG-TDDPSY
N-GALIVSGNE-KNHS---FSFACNTKRLNCFP-VL-MDILSNGLLGMVK----------
----------PSAR--IRTDRSTYLVDEI-----TNPL---EYL-----GNTAFWLILTS
ACPPYIAMSSITDYKNKA-WFQLRVSG-LFPSAYWVGQ-ALVDIPLY-------------
---CFVFLFMSL---IDYLLCFQEG-----MFSIISHI-IQIPCSVGYAVSLIFLTYVIS
FISRKGKKNSGLWSLSFYII-----TVFSVVVM-FL--DFNMD-GVLYCIIFLIPPS---
--TLT--------GCLILSMHLF----------IY------RVF
ENSGT00760000118965_1_Linker_4_5 (2745, 2873)
EGA--HIVEPFLVFLI
PFLHVFLFIFTLRCLE-WKFGKKTMRKDPIF-RISPRNNDVYQNPEEPGD----EDEDVQ
MERMRTANALV-STSFD--EMPVIVASCLRKEYAEKWKHCLSKKK--AKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEILGLLGHNGAGKSTSLKMISGDTKVTAGQVL-LK--GSRE-------GD----TPGF
LGYCPQENALWPNLTVKEHLEVFAAVRGLSKSHAT-----VAITR----LVDALKLQDQL
KSPVKMLSEGVK---RKLCFMLSILGNPSILLLDEPSTG----LDPEG-QQQIWQAIRAI
IKNTDRGALLNTHYMAEAEALCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLEQVEPL
NTEIMRLFPQAA--RQERYYPL--MVYKLPVEGVQPLSQAFFKLEKVKQTFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFA-EELDS-SIKWKLLPQEEV----------------------
ENSMMUP00000040706 (view gene)
------------------------------------------------------------
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-----------------MKYEIEIMNKDPVF-RVSPRCRETHPYPEEPEE------EDVQ
AERVQAANALT-TPNLE--EEPVITASCLHKEYYEAKKSCFSTRK--KKIAIRNVSFC--
--
PF00005 // ENSGT00760000118965_1_Domain_5 (2883, 2948)
EVLGLVGHSGSGKSTSIKMTTGFTKPTAEAVV-LQ--GNRA-S---------------
-------NSLWPKLTMKEHLELYAAVKGLGKEYAA-----LT-----------LKLQEQL
KAP------------RKLCLVLSILGNPSVVLLDELFTR----MYPEG-QQQMWQILQAT
IKNKERGALLTTHYMSEAKAVC--------------------------------------
----------------------------CIGSIQHLKNK-N-------KKMKEPTQVEAL
HTEILKLFPQAA--QQERRSSL--MAYKLPVEDVHPLSQAFFKVEAVKQTFNVE---EYS
L-SQGTLEQV----------------------------------------------FLEL
RTEQALGNVD-DRSTA-V---------------------------------
ENSPTRP00000086054 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMALASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEMVGVIFSDMF-SY----RLKFNWGYRIPVI-
---KE----HSEYTE----------------HCWAM---HGEI-FC-------YLAKY--
WLKGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
AFQAAINAAIIEVTTNHSVMEELTSVIGINMKIPPF---------ISKGEIM--
NEWFHFTCLVSFSSFIYFASLNV-----------ARERGKFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-ICFIFIMSIFMAL----------VITSIPIVFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFTAGMAQITHLDNY---
------LSGVIFPDPSGDSYKMIATFFILAFDTLFYLIFTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINPEHS-SDDSFEPVSPEFHGKEAIRIRNVIKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSATIYNTQLSEITDM
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2435)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--MNKFPDLYSDLDKCSDQ---------GIRNY--AVSMT----SLNEVFLNLEGR-S
AIDEP---------DFDIG-KQE-KIHVT--------RNTGDESEME----QVLCSLP--
----ETRKA-V-----------------------SSAALWRRQIYAVATL---------R
FLKLGRE-RRALLCLLLVLGIAFIPIILEKIMYKVTRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLIV-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRKG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNYFP-
PF01061 // ENSGT00760000118965_1_Domain_4 (2435, 2720)
VL-MGIVSNALMGIFN----------
----------FTEL--IQTESTSFSRDDI-------------VLDLGFIDGSIFLLLITN
CISPFIGMSSISDYKKNV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILFSIHL---IYYFIFL----GF---QLSWELMFVLVVCIIGCAVSLIFLTYVLS
FIFRKWRKNNGFWSFGFFIV-----SIYTCVFI-F------------------IEK----
--LAF--------NCWWVF
ENSGT00760000118965_1_Linker_4_5 (2720, 2883)
FQLD----------F--MRNLDSLDNRINEVNKTILLTTLI
PYLQSVIFLFVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANALT-APNLE--EEPVITASCLHKEYYETKKSCFSTRK--KKTAIRNVSFC--
--
PF00005 // ENSGT00760000118965_1_Domain_5 (2883, 3037)
EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVV-LQ--GSRA-SVRQQHDN----SLKF
LGYCPQEYSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGTLLTTHYMSEAEAVCDRMAMVVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGRDYLLEIKMKEPTQVEAL
HAEILKLFPQAA--WQERYSSL--MAYKLPVEDVHPLSQAFFKLEAMKQTFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQELGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSCHIP00000033368 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHFSVGQQTRALLGKNFLKKWR-----MKR
ETLSESL
PF12698 // ENSGT00760000118965_1_Domain_0 (548, 1542)
FS-CLLVLFAH-LFSS---NLHQVNDFPQLPAV--DLGRVDN--FNDS-DYVI
AFAPESK------TTQEIMNKLASAPFI------------------------------KG
RP--ISGWPDEQSMGELELNY-----SADAVRVIFNDAF-SY----HLKFLWGHRIPTM-
---KE----HGDHAA----------------HCQVM---D-ESVMC-------EASLF--
WEKGFVAFQAAINAAIIEITTNHSVMEKLMSVTGINMKMLPF---------VAQAGVM--
TDFFIFFCVISFSASIYYVSVSV-----------TQERQFMKPVMAVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFISVTAALMAL----------IVACAPVVVLTGFTVVFTLFLLYG
LSLIMLAFLTSV----------------------------LVKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRRLPAALEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNIHSDSPNDQYLIIATIFMLAFDALLYLVLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YLDKILPTE---YRRQQPP
WFFLKSSSWFQRRRA-DRAA--LENDIGPDSP-SNDSFEPVSPEFHGKEAIRIRNLKKAY
------------GRGK------H-----------------------------KKVEAL--
--E-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLVLDIYEGQITGVLGHSGAGKTTLLNILSGLSAPTS--GSVTIYNHSLSEAADL
EYISK-LTGFCPQA--NVQFGFLTVRE-NLRLFAKIKGIQPHEVE-QQVQRVLQDLEMGN
IQDVLAQNLSGGQKR-KLTFGTAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2377)
AGSDPLSRHRVWNLLRER---
---------------KSDHVVLFSTPFMDEAD----------------------------
--------------------V---------------------------LADRKVFMSNGR
LKCAGS--SLFLK---KRWGI---GYHL--SLHLN-E----------------------T
CDPDSV-TSIVKHH--------------------IPDAKL----TAQSEEKLAYI--LPL
ER--TNKFPDLYRDLESCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------GPGVR-EQL-QSGRT--------NATGSLAEPE----QVVSSFS--
----EANSS-V-----------------------SGLALWRQQLCAVAKV---------R
FLKLKSE-KRALLAILLLFGITFGPQLLEHVSYRLHQE-SYSWGLSPNMYFLSPGQPP--
RAPLTRLLVI-----NR--TGS-SIDDFIHSLRHQN
PF12698 // ENSGT00760000118965_1_Domain_4 (2377, 2769)
IDLEVDAFG----ARNG-PNESSY
N-GAITVTGDG-KDPR---FSIACNTKRLNCFP-VL-MDIISNGLLGMLN----------
----------SSEH--IQTDRSTYFEEDAS-------Y-EHGYL-----GMAFFWIPGVA
CFAPYIAMGSIGDYKKKV-HSQLRISG-LYPSAYWFGQ-ALADVPLY-------------
---LSILLLMQI---MDYIFSPDEF-----VFIIQNLA-VQTLCIIGYVSSLVFLTYVIS
FIFRRGRENSGIWSFFFLLV-----TLFAIVANYL---NEYGF-LGLFLCTILIPPF---
--TLI--------GVLLIFSEIS----------PDS------VDYLGASEQQVAFLTLLI
PYLHFFIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFILRCLE-MKFRKKPMRKDPVF-RISPRSSAVFANPEKPEG----EDEDVQ
MERRRTADAVA-APDSE--EKPAIVASCLRKEYAGRKKNCFAKRK--KKVAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTAVKMITGDARPTAGQVL-LA--GGSG-------GA----PPGF
LGYCPQESALWPSLTVREHLEVSAAVKGLRRADAA-----AAIAR----LADALKLQDQM
ALPAKALPEGAK---RKLSFALSILGSPAVLLLDEPTTG----MDPEG-QLQMWQLIRAS
FRNTARGALLTTHSMAEAEAVCDRVAVMVSGSLRWVGPQARS------------------
---------------------------ECVGSIQHLKSK-FGRGYLLEMKLKSLARLEAL
HGEVLRIFPQAA--RQERFASL--LVYKLPVEDVHPLSHAFFCLETGESACCEVRSSGHP
ISLFLPLLQV----------------------------------------------FLEL
CKEQEWDNSD-EEVDL-SVKWKLLPEEP-----------------------
ENSCPOP00000029711 (view gene)
------------------------------------------------------------
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---------------------------------------MI-NFHV-------HCPRY--
WNNGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
ALQTVINAAIIEITTNHSVMEELMSVTAINMKTLPF---------VSKSVPQ--
IGIFILFCLIYFFPFIYFVSLDV-----------TKERKKHKNLMKTMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IVTSIKIFIMTGFVVIFTLLCLYG
LSLVALAFLMSV----------------------------LLRKAALT---NLIM-----
LL-LTIFWGC--------VGFVAFYVQIPSSLKWILSIWSPFTFAVGMAQIFQLDYN---
------STGVTFPDPSGDSYIMISIFAMLVFDCFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---NECHYSP
LFFLNSSSCFQSR-KTDNKV--FEKDTDSELH-FDDYFEPVAPEFQGKEAIRIRNVKKDY
-------------KEK------S-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GFNFDIYESQITAILGHSGAGKSSLLNILSGLSVPTQ--GSVTVYDKNISEMQDL
EEIRK-MIGVCPQY--NVQFDILTVKE-NLSLFAKIKGIHPHEVE-QKVRQVLLELDMEN
IQNNLAEDLSEGQKR-KLTFGITILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2298)
AGLDPFSRYRVWSFLKER---
---------------RENHVILFSTQLVDEAD----------------------------
--------------------I---------------------------LADRKVIMFNGR
LKCAGS--SVFLK---RKWDL---GYYL--SVYKN-E----------------------I
CDQEQI-TSFINHH--------------------IPDAKL----KTENKEKLVYT--LPL
ER--TNKFPDLFRDLDKCSSQ---------GMMSY--DISMS----TLSEVFMNIEGK-S
TINQG----------------FG-HLEMM--------SNSESFNEMQ----PAYPSLP--
----EVQKP-V-----------------------SDMERWRMQVCAIARL---------R
FLKLIRE-RKTLLILLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2298, 2718)
IFGMSLCPLIIERITYYMMQQ-TVDWEFKTDSYFLSPGQLP--
QDFRTSLLII-----NH--TES-DIEDFIQSLKHQNILLEVDDFK----NRNG-TNALSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRMHCFP-VL-MNIISNGLLRMFN----------
----------QTQY--LRLERSPLSLDMM-------------VVWTGLVDGSLFLLFVVC
SISPYIAMSSVSDYKKKA-KRQLWISG-LYPSAYWFGQ-ALVDINLF-------------
---NLILLLVHL---IGYLIRI---TDN---YISRRTIFGMVTTTFGYAVSLIFLTYVIS
FVFRKRRKYSGLWTFCFFIL-----TSV-LDSL-IW--ENFHL-TTIISTMIFVPSS---
--TMN--------VFLM
ENSGT00760000118965_1_Linker_4_5 (2718, 2873)
FLLERA----------YARYTDSEE---TKFDLSEAELLVCLI
PYFQALLFIFVLRCME-LKYGKNVMRKDPVF-RISPQSPEARPNPEEP--GD--EDEDVQ
AERIRTSTALT-TSNLD--EKPTIIASCLHKEYAGQKKNCFSKRK--KKLAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFSIK
KGEVFGLLGPNGAGKSSSIRMIAGITKPTAGEVK-LK--ECGTA-LDDQGED---M-VTL
PGYCPQENVLWPRLTMKEHLEVYAAVKGLRKGDSA-----VIISR----LVNTFKLHEHL
NMPVRNLAAGTT---RKLCFVLSILGDSPVLLLDEPSTG----IDPAG-LHQIWQAIQMS
VKNKDRAILLTTHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILQLKVEEPSQVPLV
HSEILKCFPQAA--QPERYSTL--LTYKLPIGNVYPLSQAFHKLEQVKHTLNLE---DYS
L-SQCTLENV----------------------------------------------FLEF
SKEQELENVN-EEVDE-TMRWKLLPHSEEP---------------------
ENSDORP00000003071 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHLSMGQQTWALLCKNCLRKQR-----MKR
ETSLEW
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
FFS-CLLLLFAC-LFSS---NLHQVNDSPHMSAV--NLGRVDN--FNDS-DFAV
HFSPESN------TTQEIMNKVASAPFM------------------------------KG
IS--IMGWPDEQRMNELDFNL-----SVDPVKIIFKDMF-SY----HLKFPWGNRIPSR-
---KE----HIDHSA----------------HCQVV---G-PNITC-------ESSVF--
WEKGFVPLQAAINAAIIEITTNCSVMEELMSVTGINMRILPF---------IAQGGVT--
TDFFIFVCIISFSSFIYYVSINV-----------AQERQNMKSFMIMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFVLLMATLMTI----------IAKTTHIVVLTGFMVVFILFLLYG
LSLISLAFLMSV----------------------------LIRKPFLA---GLAI-----
FV-LTVFWGS--------LGLMTLYRHLPAFWEWTLCVLSPFAFTAGMAQLIHLDYD---
------MNSNVHLDSSNNSYLIIAILFVLVVDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKILPSK---YGRHHSP
LFFLKSSLWFQHQKS-KHEL--LENEVDSDPS-LDDSFEPVLPEFQGKEAIRIKNLKKEY
------------T-GK------Y-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLVFDIYEGQITALLGHSGAGKTTLLNTLSGLLPPTS--GSVTIYNQTLSEVADF
ETISQ-LTGVCPQS--NIQFGFLTVRE-NLRLFAKIKGILPHEVE-KEVQQVLQNLEMEN
IQGSLAENLSGGQKR-KLTLGIAILGDPQV--LLLDEPTAGLDPVSRHCVWNLLKER---
---------------KSDRVILFSTHFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPESV-TTLVKQH--------------------IPDAKL----TAQNEGKLVYI--LPF
ER--TNKFPDLYRDLDRCSHQ---------GIEDY--GVSMT----TLNEVFLKLERE-S
IVDEP---------DLGIW-GQL-QSDGT--------KDTGDFVELE----QVLSSLS--
----ETRNT-V-----------------------SGMALWRQQLCAMAKV---------R
FLKLKRG-KKKLLAMLLLWGISFFPELLDNLFLESYKK-NSPWGLSPNMYFLSPGQQP--
EDPLTPLLVI-----NK--TGS-SIEDFLHSLKQQNIALEVDAFG----TRNG-TDEPSY
N-GAIIVSENE-QDRR---FSIACNTKRLSCFP-VL-MDVISNGLLGVFN----------
----------SSKH--IQTERSTSFGEYLF-------Y-EHGYLFNPLLSNLFFSSAVAA
CLPPYIAMSSIGDFKRKV-HSQLWISG-LFPSAYWFGQ-ALVDLPLY-------------
---FLILLLIQM---MDYVFNPEEI-----TVILQYLL-IQILCNIGYASSLIFLTYVIS
FIFHNIRKNSSLWSVIFFIV-----TNFLIVVSDL---NDYRF-LTLFFCTILIPPF---
--TLI--------GSLFIYSGFS----------PDA------ADYLGASESHVLFLALLT
SYLHFFIFLFVLRCLE-RHFGKKSLRKDPVF-RISPTSSDVFPNPEEPEG----EDEDVQ
IERTRAANAMA-VLEMD--EKPVIIANCLRKEYACRRKNCFSKQK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEIIGLLGHNGAGKSTMIKMITGDTKPTAGQVI-LK--RSSE-------ED----TQGF
LGYCPQENLLWPVLTVREHLEVYAAVKGLRRKHAS-----ITIAR----LVNAFKLQAQL
QAPVKTLAEGVK---RKLCFVLSILGNPSVLLLDEPSTG----MDPEG-QQQMWQAIRAT
IKNMNGGALLTTHYMVEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CLGSPQHLKSK-FGNDYLLEMKVKSLSQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLRIEDVRPLSQTFFKLELVKQNFSLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELDDFD-EEINS-SMKWKLLPQEDP----------------------
ENSCHOP00000001398 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSEREISVCQQTRALLCKNILKKWR-----MKR
ETLMEWLTS-LFLLLSLY--LF-S--DIHQVNDFSSRPVM--DMGRVDS--FTRA-EFTI
VYTPVTN------TTQQIMNKVASTPFM------------------------------AD
SK--ILGLSDEKNIEELIEKY-----PEEIVRVIFTNTF-SY----HLKFLLGRRIPTK-
---KE----HEDHAX----------------XXXXXXXXXX-XXXXXXXXXXXXXXXX--
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XX-XXXXXXX--
XXXXXXXX-XXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXX------
------------------------------------------------------------
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---XXXXXXXXX-XXX---XX--XXX----------XXXXXXXXXXXXXXXXXX----XX
XXXXXXX--XXX----------------------------XXXXXXXX---XXXX-----
XX-XXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLLRVDYD---
------LNSNAFLAPLESSYLIIATHFMLALDIFLYLTLTIYFEKILPXX---XXXXXXX
XXXXXXXXXXXXXXX-XXXX--XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXIRNVTXXX
-------------XXX------X-----------------------------XXXXXX--
--X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XSVTIYNNKLPEMADL
ENISK-LIGVCPQS--NVQFEFLTVKE-NLRLFANIKGILPKEVD-KE------------
-----------------------------V--LLLDEPTAGLDPFSRYQVWNFLKKC---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LAERKVFLSKGM
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CVQEKV-TSLVKQH--------------------IPDAKL----SARSEGKLIYT--LPI
ER--TNKFPDLYKDLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIHEADVG---------IL-GEV-QEERA--------GDTERLVEME----QVLSSLD--
----EM-RETT-----------------------SGMALWRQQICAIARV---------R
FLKLKHE-RKALLSLLLILGIGFFPLLLEYIILKIYQS-SYTWELSPHTYFLAPGQQP--
RNPLTPLLII-----NK--TGT-RIDDFIHSVEHQDIALEVDTFG----TRNG-TDDPSY
N-GAIVVSGDE-KNYSFS-L--ACNTKRLNCFP-VL-MDIVSNGLLGMFKP---------
-----------SAR--IQTDRSTFYREE-------------LSNPFEVLGHTMFWLILAS
GCSPFIAMSSIDDYKX-XXXXXXXXXX-XXXXXXXXXX-XXXXXXXX-------------
---XXXXXXXXX---XXXXXXXXXX------X-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXI-----TTISLIVVFF---DVFES-GTTLSIIFLIPHA---
--TLI--------GCLILSLRI------------VLTSAFI-EE----RSDVEPFLVFLI
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX----XXXXXXX
XXXXXXXXXXX-XXXXX--XKPVIIASCLRKEYAGKRKHCFSKRK--KKIATRNISFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 2960)
GEVLGLLGHNGAGKSTFIKVVTGDTKPTAGQVL-LK--GSS-------GGD----TLGF
LGYCPQEDALWPGLTVREHLEVAA--VGLRGAAAA-----IARXX----XXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXX--XXXXXXX----XXXXX-XXXXX-XXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX---------------------------
---------------------------XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXVE
FTEILRLFPQAA--RQERYSSV--MVYKLPVEDVRPLAQAFFKLENVKRSFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EELDP-SINWMLLPQEEA----------------------
ENSCCAP00000030628 (view gene)
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MKHGNEIMSKDPVF-S-----REIHPNPEE-------------
---VKAANALT-TPNLE--EKPVITASYLHQEYCETKKSCFSARK--KKIAIRNVSFCVK
KG-----LS
PF00005 // ENSGT00760000118965_1_Domain_5 (2890, 3037)
HNGAGKSSSIKVITGYTAG-----V-VC--DIRASVM-QQYDN----SLKF
LGYCPQENSLWPELTMKEHLELYAAAKGLGKKDAT-----LSISWYREKLMEALNLQEQL
KAPVKTLSEEIK---R------NILRNPSVVLLDEPFTG----MDPKG-QQQMWQTLWAT
VKTKEWGALLTTHYMSEAKAVCHHVAMMVSGTL---------------------------
---------------------------RCICCIQHLKNK-FGKDYLWNLF----------
-TQRFCIFPQALTLLPDRYSSS--MAYKLPAERVHPLSWDFFKLDAVKQTFNLE---EYS
F-SQATLEQK----------------------------------------------QCEA
SLDADVGTTF-L-VQP-VKQSA-----------------------------
MGP_SPRETEiJ_P0032180 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRLGQQMWALLCKNWLRKFR-----MRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLLEWLFS-LLLILFVY-QLSS---NLHQVHDAPEMSVV--DLGRVDN--FNDS-NYMM
VFAPESE------ATHEIMTKVASAPFM------------------------------KG
RT--VVACPDEKSMNELDLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPKT-
---KE----HKDHSA----------------PCEPL---N-NKMIC-------ENSAF--
WEKGFVAFQAAINAGIIEMTTNHSVMEELMSVIGSNMKMPPF---------IAQGGVA--
TDFFIFFCVISFSSLIYYLSVNI-----------TQERQYMTTLMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILVVAVLMSL----------IVKSAQVVVLTGFMVVFLLFLFYG
LSLITLSFLMSV----------------------------LIKKPFLT---GLAV-----
FL-LTVFWGS--------LGFTALYKHLPAFVEWTLCFLSPFAFTTGMAQLIHLDYD---
------VNSNVNLNSPNNSYLIMATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKITLSK---YGHQRSP
LFFLKSSYWFKRRGA-SHVV--LENEIDSDPS-LNDSLEPVSPEFQGKEAIRIKNLKKEY
------------S-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINTLSGLSPPTT--GSVTIYNQTVSEMDDS
DAVLT-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQQVLQDLEMEN
IQDILAQNLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPLSRHRIWNLLKER---
---------------RVGRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLS-E----------------------A
CDQEGI-TSLVKKH--------------------IPDARL----TTQSEERLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIEDY--GVSMT----TLNEVFLKLEGK-S
MADES---------DVGIC-GRL-QSDGA--------RDMESLVELE----QVL-SLD--
----SSGSS-V-----------------------SGMALWRQQLCAVAKV---------R
FFKLKNE-RKSLMTVLLLFGISFVPQLLEHLVYKVYHK-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NR--TGS-SIDNFVHALRQQGIALDLDALG----TRNG-TEEALY
N-GAITVLGEE-KDLR---FSVACNAKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2771)
-VL-MDIISNGLLGIFN----------
----------SSER--IQTDRSTVFEEHML-------Y-EYGFM-----SNAFFWIPVAA
SLTPYIAMGSISDHKKKV-LSQLWTSG-LYPSAYWCGQ-ALVDIPIY-------------
---FLILFLMQI---MDSVFSSEEF-----ISVMESLL-IQIPCSIGYASSLIFMTYVIS
FIFRNGRKNSGIWSFFFLIV-----TIFFIIATDI---NEYGF-LELLICTFLVPPF---
--TLI--------GSLLIFSEVS----------YDS------VDYLGASESQLVFLALLI
PYLHFLLFFF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-RYLRKKSLRVDPVF-RISPRSCPAVPNPEEPGE----EDEDVQ
MERVRTTGAMA-TLQTD--EKPVIIASCLRKEYTGRTKRCFSKTK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTIPTAGQVF-LK--GSGG-------GA----ALGF
LGYCPQENVLWPNLTVKEHLELYAAVKGLKKKDAV-----VTITR----LVNALKLQDHL
KALVRTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPSQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSEAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFG-EEANS-SVKWKLLPQEEL----------------------
MGP_SPRETEiJ_P0032182 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MKE--LSVRQQTRALLHKILLKKWR-----RKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWSIP-VIIGLHMG--LFS---YLARNIQVLEVPPQ--DLGSLNE--FNGSSLV-V
VYTPISN------ITQQIMNKTTFAPTM------------------------------KG
TR--IIGVPSIEDLDEVLLHN-----IPDALGVIFNDSF-SY----QLKVLRMYGNPFF-
---K------EDLLA----------------HCWDT---HS-QAFC-------SLSKY--
WERGFVALQTAINAGIIEVTTNHSVMEELMSIDGINMKTLPF---------IPRDLSD--
YEIFILFCLLYFSSFIYFASSNV-----------TKERKQCKEVMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIISTFIAI----------IITSTQIIMMTGFLVIFMLFFLYG
LSLIAVTFLMAV----------------------------LLQKAVLT---NLIV-----
LF-FTLFWGC--------VGFTVLHKELPPSLEWVLSICSPFAFTSGMAKVIFQDYN---
------LNGVVFPDPSGESYVMIAVFFILAFDSLLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---AEHRSAP
LFFLNPTSCFR-KTANRNKV--IERDLDPELP-SDEYFEPVDPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA--GSVTVYNKNLSDMQDL
KEIRK-AIGVCPQH--NVQFDALTVKE-NLTLFAKIKGILPQDVE-QEVQQILSELDMQN
IRDDLAEHLSEGQKR-KLTFGIATVGDPQI--LLLDEPTVGLDPFSRQRIWGFLKER---
---------------RADHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVLISNGA
LKCTGS--SVFLK---RKWGL---GYQL--SLFMD-D----------------------T
CDSEQL-TSFINHH--------------------IPCAKL----KAKTKEKLVYI--LPL
ER--TSEFPEFFSDLDKYSGQ---------GLMSY--EVSMS----TLNEVFLNLEGE-P
STKQD----------------FE-KRETA--------TDSESLNDME----VVYPSLS--
----QVQET-V-----------------------STMSLWRMQVCAIAWL---------R
ILKLKRE-RKAFLIILLLLGIALLPLVIEYVANALLEV-KNNWEFKTDLYFLSPGQLP--
QGLRTSLLVI-----NN--TES-NIEDFLQSLKHQNIVLEVDDFE----NRNA-TNSLSY
N-GAIIVSGRQ-KDYR---YSAVCNTKRLHCFP-IL-MNVISNGILHMLN----------
----------HTQY--IRIKEDIFLPFIV-------------LVWTGIQETCLFILCVIC
SLSPHIAMSSVSDYKKKA-DSQLWISG-LYPSAYWCGQ-AVVDISLF-------------
---SGMLLTSYF---TSYTSKL---LNI---DMTSEIVFSVIVLALGCAASLVFLTYVIS
FVFGKRKKNSTLWSICFLLV-----IAITFEKV-AN--GPFNE-ALVISATMLVPSF---
--ALN--------GLLVVLEMRA----------YQYYIEFEE---IKHGLSAVDLLLCLI
PYIHTLLFIFVLRCLE-LKYGKNVVRKDPIF-RIAPQSLKGQPNPEEPID----EDENVQ
AERLRTSNALS-TPNLD--EKPVIIASCLHKEYAGQKKRCCSRRT--RNMAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE-LK--RLSSA-VGHQGDS-----RAE
FGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAV-----VAISR----LVNALKLHDQL
NVQVQNLAAGTT---RKLCFALSILGNSPVLILDEPSTG----LDVSG-KQQVWQAIQAA
VKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL---------------------------
---------------------------RCIGPIQHLKRK-FGQDYVLELRVKDVSQEPLV
HREILKLFPQAA--RQDRCFSL--LTYKLPVTDVHPLSQAFHKLEAVKHGFDLE---DYS
L-SQCTLDRV----------------------------------------------ILEL
SKEQELGAVY-EEDDM-TLGRKLLPPSDEL---------------------
ENSNLEP00000002652 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRKISVCQQTWALLCKNFLKKWR-----TKR
ESLMEWLNS-L
PF12698 // ENSGT00760000118965_1_Domain_0 (552, 1542)
LLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVNN------TTQQIMNKVASTPFL----------------------------A--G
KE--VLGLPDEESIKEFMANY-----PEEIVRVTFTNTY-SY----HLKFLLGHGMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSSFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTQFIILSGFMVVFSLLLLYG
LSLVALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGC--------LGFTTLYRHLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPSDGSNLIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGYRRPP
LFFLKSSFWSQTQKT-DHVA--LEDEMDADPS-SHDSFEAVPPEFQGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2382)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------I
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GDVALWRQQICAIARV---------R
LLKLKHE-RKALLALLLILMAGFCPLLVEYAMVKIYQN-SYTWELSPQLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEV
PF12698 // ENSGT00760000118965_1_Domain_4 (2382, 2718)
DAFG----TRND-TDDPSY
N-GAITVCGNK-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSVH--IRTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFAFIYL---MSYISDFEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFRKGRKNSGIWSFCFYVI-----TVFSVAEF-AF--NIFES-DIPFIFTFLIPPA---
--TMI--------GCLF
ENSGT00760000118965_1_Linker_4_5 (2718, 2872)
LSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFTLRCLE-WKFGKQSMRKDPFF------SSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFN--EKPVITASCLRKEYAGKRKGCFSKRK--NKIA
PF00005 // ENSGT00760000118965_1_Domain_5 (2872, 3037)
LRNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSGG------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDP-SVKWKLLPQEEH----------------------
ENSP00000269081 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMALASFM------------------------------KG
RT--VIGTPDEETMDIELPKK-----YHEMVGVIFSDTF-SY----RLKFNWGYRIPVI-
---KE----HSEYTE----------------HCWAM---HGEI-FC-------YLAKY--
WLKGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
AFQAAINAAIIEVTTNHSVMEELTSVIGINMKIPPF---------ISKGEIM--
NEWFHFTCLVSFSSFIYFASLNV-----------ARERGKFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-ICFIFIMSIFMAL----------VITSIPIVFHTGFMVIFTLYSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFTAGMAQITHLDNY---
------LSGVIFPDPSGDSYKMIATFFILAFDTLFYLIFTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINPEHS-SDDSFEPVSPEFHGKEAIRIRNVIKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSATIYNTQLSEITDM
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2512)
AGLDPFSRHRVWSLLKEH---
---------------KVDRLILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNKFPDLYSDLDKCSDQ---------GIRNY--AVSVT----SLNEVFLNLEGK-S
AIDEP---------DFDIG-KQE-KIHVT--------RNTGDESEME----QVLCSLP--
----ETRKA-V-----------------------SSAALWRRQIYAVATL---------R
FLKLRRE-RRALLCLLLVLGIAFIPIILEKIMYKVTRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLIV-----NN--TGS-NIEDLVHSLKCQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNCFP-VL-MGIVSNALMGIFN----------
----------FTEL--IQMESTSFSRDDI-------------VLDLGFIDG
PF12698 // ENSGT00760000118965_1_Domain_4 (2512, 2769)
SIFLLLITN
CVSPFIGMSSISDYKKNV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILFSIHL---IYYFIFL----GF---QLSWELMFVLVVCIIGCAVSLIFLTYVLS
FIFRKWRKNNGFWSFGFFII-----LICVSTIM-VS--TQYEK-LNLILCMIFIPSF---
--TLL--------GYVMLLIQLD----------F--MRNLDSLDNRINEVNKTILLTTLI
PYLQSVIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANALT-APNLE--EEPVITASCLHKEYYETKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVV-LQ--GSRA-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGTLLTTHYMSEAEAVCDRMAMMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGRDYLLEIKMKEPTQVEAL
HTEILKLFPQAA--WQERYSSL--MAYKLPVEDVHPLSRAFFKLEAMKQTFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQELGNVD-DKIDT-TVEWKLLPQEDP----------------------
ENSJJAP00000001218 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVNREISVCQQTWALLCKNLIRKKR-----MRR
DTILECLYS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
AILLVSLY--MFP---EVHQVYDFS-FPTV--SLGRIDS--FNDS-TFTI
AYTPDTQ------TTQRIMNKVSSASFM----------------------------K--G
IK--VMAFPEERNMTESHSSD------EHAVRVIFTNTY-SY----HLKFPEGAGIPTI-
---KE----HEDHSA----------------HCHMY---G-MTMFC-------YSSMF--
WTDGFVTLQAAINAAIIEVTTNHSVMEELMSVTGTYMKTDPF---------IAQGGIM--
TDFFIFICIICFSPFTYYVSAGV-----------TRERKRMKGLMKAMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-TAIICIMSLFLAL----------IVKEVQFVIRTGFMAVFSLFFFYG
LSLITLSFLMSI----------------------------LLKKSFLT---DFVV-----
FI-LTVFWGS--------LGFASLYRYIPMPLEWILCVFSPFAFTLGMAQLLHVDFD---
------INSNT--DTMSNSNLIMATTFMLFFDTSLYLVLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPNE---YGHRYSP
LFFLKSSFWSQQKM----VV--LENEMDYE-F-SDESFEPVSTEFHGKEAIRIRNLTKEY
-------------SGK------P-----------------------------KCIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLALDIYEGQITAILGHSGAGKSTLLNILGGLCVPTK--GWVTIYNNKLSEMNDL
ECISK-FTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIHPHEVN-NEVQRILLELEMKN
IQNVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2366)
AGLDPFSRHRVWNLLKER---
---------------KAGRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-G----------------------M
CVQEKI-TSLVRLH--------------------IPEARL----SAESEDKLSYI--LPL
ER--TNKFPDLYRDLESCFDL---------GIENY--GVSMT----TLNEVFLSLEGK-S
AVDQS---------DASAL-LDT-QAAGT--------RDTAGFVEME----QLVCSLN--
----GMKKT-Q-----------------------EGMALWWQQLRAVTRL---------R
FLKLKHE-RKAICMLILAFGVGLLHILASNAHRIAYQD-DYCWDLSPNMYFLAPNQQP--
RDPLTNLLII-----NK--TGT-KI
PF12698 // ENSGT00760000118965_1_Domain_4 (2366, 2703)
DDFIHALEQQNIALEVDAFG----ARNG-TDETLY
N-GAIIVSGDK-KNYN---FTLSCNTKRLNCFP-VL-MDIVSNGLLGLFT----------
----------PSVR--IQTDRSTFYKNNP---HGFNCY---NFM-----FYIISWILLMT
CVSPYISMTNIDDYKSKT-QFQLWASG-LYPSAYWFGQ-ALVEVPIY-------------
---SLLILFMYV---AYYAVHLQGV-----VFATLDLF-IQILYIVGYATSIIFMTYMIS
FLSRKGRKNSGIWSFCFYIV-----TLFSVTFE-LI--EYYRE-TALFCITLLIPPA---
--
ENSGT00760000118965_1_Linker_4_5 (2703, 2873)
TLV--------GCTLLHFEYR----------A-----YNDLV-FIEPARKFVYLLFLT
PFVHIIIFLVILRYLE-FKLGKKTMRKDPVF-RIASRSAHVCPNPEEAEG----EDEDVT
RERARTADALT-SADFE--EKPAIIASCLRKEYSDKKKCFYFKKK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTCIKMITGETKPSAGQVL-LN--GSSR-------GD----DLGF
LGYCPQENNLWPNLTVREHLEVFAAVKGLSKGDAM-----VAITR----LVDALKLQDQL
KAPVKTLSEGVK---RKLCFVLSVLGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FANSKRGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKEYQLEMKVRTPAQVEAL
HSEILRIFPQAA--RQERYASL--MVYKLPMEDVRPLSQAFFKLET--------------
------------------------------------------------------------
---------------------------------------------------
ENSVPAP00000000130 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----EWLNA-LFLLLSLY--LYP---DIHQVNDFSSLPPM--DLGRVDS--FSAS-KFAI
AYTPVTN------TTQQIMKIVASASFM----------------------------KXXX
XX--X-----XXXXXXXXEFY-----PEEVVRVIFTNTS-SY----NLKFLLGHRIPIR-
---KE----YRDHTX----------------XXXXX---X-XXXXX-------XXXXX--
XXXXXXXXXXXXXXXXXXITTNHSVMEELMSVTGKNMKIYPF---------ISQGGVL--
TDFFIFFCIISFSPFTYYASINV-----------TRERKKMAGLMRMMGLRNSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AAFVFIVALFLTL----------IVKSAQFVILTGFLTVFALFLLYG
LSLIALTFLMSV----------------------------LVKKSFLT---GLVM-----
FL-LTVVWGS--------LGFMALYRYLPASLEWILSFLSPFAFMLGMTQLLHLDYD---
------LNSNAFLNPSDSSNLIIATNFMLVFDIFFYLALAIYFEKILPNE---YGHRYSP
LFFLKSSFWSRQRWA-DHMA--LEDEIDSSPS-SNDTFEPMSPKFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
--K--DLVFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMVDL
ENISK-LTGVCPQS--NVQFDFLTVRE-NLWLFAKIKGIQLHKID-K-------------
----------------------------EI--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-A----------------------M
CVQEII-TSLVKQH--------------------IPEAKL----SAESEGKLVYT--LPL
ER--TSKFPELYEDLDRRPGL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TIDES---------GIANF-REA-QAEGA--------GDTEKLVEME----QFLSSVN--
----ETKKT-T-----------------------GGMALWGQQICTIARV---------R
LLKLKHE-RKALLSLLLILGVGFCPLLLEYIFVKIYQS-SYTWELSPHLYFLAPGQPP--
RDPLTQLLII-----NK--TGA-SIDDFIHSVENQNIALEVDMLG----TRNG-LDDPSY
N-GAIIVSGNE-KSYS---FSLACNTKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSAH--IQTDRSTFWGEEQ-----NNPL---DFL-----GYAPFWLTLSS
CCAPYIAMSSIDDYKXXX-XXXXXXXX-XXXSAYWFGQ-ALVDVPVY-------------
---CLIFLFMYL---MDHGLNLQDS-----IFKTVDQI-IQIPCAIGYATSLIFLMYVIS
FIFRKGRKNSGIWSFCFYIV-----TILAVIGF-LL--DNSGH-GVLYAVTFLIPPA---
--TLI--------GCEFLSFHLF----------TF------YISEEE-PGSIEAFLVFLI
PFLHFIIFLFILRCLE-WKFGKRSMRKDPFF-RISPRSWDACPNPEEPEG----EDEDVQ
LERVRTAVALN-STD-D--EKPVIIASCLRKEYAGKRKHCFVKRK--KKTATRNISFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GRGG-------GD----ALGF
LGYCPQENALWPSLTVQEHLEVFAAVKGLRKADAM-----AAVTR----XXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-XXXXXQAIRAT
FRNTERGALLTTQYMAEAEAICDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-YGKDYLLEMKVKTPTQEEAL
HSEILRLFPQAA--RQERFPSL--MVYKLPVEDVRPLAQAFFKLEK--------------
------------------------------------------------------------
---------------------------------------------------
ENSRBIP00000000287 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----IKR
ESLMEWLNS-LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HRDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFFCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSKYKPLDL
LSSILVRN----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------L----------------------------------SLTGLVGVPP------
-----------------------------------------------------HL-----
VL-FGAVWG------------PALYRHLPSCL-------VPFAA-SHLGMLLHLDYD---
------LNSNAFPHPLDGSNIIVATDFMLAFDTCLYLALAIYFEKILPNE---YGHRRPP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRILSVVLIV
FLPFSPPLFSSLYLIF------L-----------------------------SFLFFF--
--L--D
PF00005 // ENSGT00760000118965_1_Domain_3 (1687, 1840)
LVFDIYEGQITAILGHSGAGKSTLLNILSGLSIPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KESF---AGIGNEN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2471)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYHH-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNVALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KSYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------
PF12698 // ENSGT00760000118965_1_Domain_4 (2471, 2705)
PSVH--IQTERSTFLENGQ-----DNPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-FQIPCAVGYSFSLIFMTYVIS
FLFHKGRKNSGIWSFSFYVI-----TVFSVAGF-VF--NIFES-DIPFIFTFLIPPA---
--TM
ENSGT00760000118965_1_Linker_4_5 (2705, 2873)
I--------GCLFLSSHLL----------FS------PLFSEE-RMDVHLSFIF--
------SFSFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPEEEP----------------------
ENSNGAP00000025231 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHFKVGQHTWALLCKNCLRKWR-----MKR
ETLME
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WFFS-FLLVLFAY-LLSS---NLHQVHDSPQIPDT--DLGRVDN--FNDS-NYIV
AFAPESQ------TFQEIMNKVASTPFM------------------------------KG
RT--IMACPDEKSMNELDLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPKV-
---KE----HKDHSA----------------HCQEM---N-KKITC-------ENSIF--
WEKGFVAFQAAINAAIIEITTNHSVMEELMSVIGTNMKILPF---------IAQGGVT--
TDFFIFFCIISFSSFIYYLSVSV-----------TKERQYMKSLMAVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFVLVTATLMAL----------VVKSAQVVVLTGFVVVFLLFLLYG
LSLITLAFLMSV----------------------------LLKKPFLT---GLAV-----
FL-LTVFWGS--------LGFTALYKHLPAFMEWILCFLSPFAFTTGMAQLIHLDYD---
------VDSNVYLDSSDNSYLIVATLFMLVFDALLYLALAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPAK---FGHQHSP
LFFLKSSFWFQYQGA-NHVV--LENEIDSDPS-LNDSFEPVSPEFQGKEAIRIKNLRKEY
------------T-GK------H-----------------------------GKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVFDIYEGQITALLGHSGAGKSTLINTLSGLSPPTA--GSVTIYNQVLSELAEF
ETVMK-LTGVCPQS--NVHFDFLTVRE-NIKLFAKIKGILPHEVE-QEVQRVLRDLEMEN
IQDILAQNLSGGKKR-KLTLGIAILGDPQI--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2503)
AGLDPLSRHRVWSLLKER---
---------------KAERVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--RYDG-------------------------V
TSPPSV-AN--------------------------------------S------------
-P--QSILYTLYRDLDKCSNQ---------GIEDY--GVSMT----TLNEVFLKLEGK-S
VTDES---------DVGIW-GQL-QSDGE--------KGRGSLVELQ----EMLSSLS--
----GTRKT-V-----------------------SGTALWRQQLCTVAKV---------R
FLKLKNE-RKSLLTILLFLGISFLPQLLEHLFYELYHK-SYSWGLSPRMYFLSPGQPP--
QDPLTHLLVI-----NQ--TGS-SIDNFIHSLRLQNISLEVDAFG----TRNG-PEESLY
N-GAITVSGDE-KDHR---FSIACNTKRLNCFP-VL-MDIISNGMLGILN----------
----------SSER--IQTDRSTFFEE-------------HG
PF12698 // ENSGT00760000118965_1_Domain_4 (2503, 2770)
YM-----TNAFFWIPVAA
GLTPYIAMSSISDYKKGV-LSQLWISG-LCPSAYWCGQ-ALVDIPLY-------------
---FLILLLMQI---MDCVFSQEEI-----LFIVENLL-IQILCSIGYASSLVFLTYVIS
FIFRNGRKNSGIWSFFFLII-----TIFSIVAMDI---NEYGF-LGLVFCTLLIPPF---
--TLI--------GSLLIFSEIS----------YDS------MDYLGASESQIVFLALLI
PYLQFLIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FVLRCLE-RYFRKKSLRMDPVF-RIPPRSCDVFPNPEEPVE----EDEDVQ
MERMKTANATS-ILQIE--EKPAIIASCLRKEYAGQKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGKVLGLLGHNGAGKSTTIRMITGDIKPTAGQVF-LK--GSGE-------GD----ALGF
LGYCPQENVLWPLLTVKEHLEVYAAVKGLNKGDAL-----VTITR----LVDALKLQEQL
KAPVKTLSEGVK---RKLCFGLSILGNPSVVLLDEPSTG----MDPEG-QQQM-RAIQAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVNAIAQAEPL
HAEILKIFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFKLERLKENFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQEMDDIQ-EELDP-SVKWKLLPQEEL----------------------
ENSBTAP00000009067 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHFSVGQQTRALLGKNFLKKWR-----MKR
ETLSEWLFS-CLLVLFAH-LFSS---NLHQVNDFPQLPAV--NLGRVDN--FNDS-DYII
AFAPESK------TTQEIMNKLASAPFI------------------------------KG
RT--ISGWPDEQSMGELELNY-----STDAMRVIFNDAF-SY----HLKFLWGHRIPTM-
---KE----HRDHSA----------------HCQIM---D-ESVIC-------EGSLF--
WEKGFVAFQAAINAAIIEITTNHSVMENLMSVTGINMKILPF---------VAQAGVL--
TDFFVFFCVISFSAFIYYVSVSV-----------AQERQFMKPLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-TGFISITATLMAI----------IVTYAPVVILTGFTVVFTLFLLYG
LSLITLAFLMSV----------------------------LVKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRRLPAALEWTLCLLSPFAFTAGMAQLIHLDYD---
------VNSNIHSDSPNDQYLIIATIFMLVFDALLYLVLTLYLDKILPTE---YGRQQPP
WFFLKSSSWFQRRRA-DRAA--LENDIDPDSP-SDDSFEPVSAEFHGKEAIRIRNLKKAY
------------GKGK------H-----------------------------EKVEAL--
--K--GLVLEVYEGQITGILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLSAPTS--GSVTIYNHSLSEAADL
EHISK-LTGVCPQA--NVQFGFLTVRE-NLRFFAKIKGIQPHEVE-QQVQRVLQDLEMGN
IQDVLAQNLSGGQKR-KLTFGTAILGDPRV--LLLDEPTAGSDPLSRHRVWNLLRER---
---------------KSDHVVLFSTPFMDEAD----------------------------
--------------------V---------------------------LADRKVFMSNGR
LKCAGS--SLFLK---RKWGI---GYHL--SLHLN-E----------------------T
CDPDSV-TSIVKHH--------------------VPDAKL----TAQSEEKLEYI--LPM
ER--TNKFPDLYRDLESCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AFDES---------GPAVS-EQL-QSGRT--------NDTGSLAEPE----QVVSSFS--
----EASST-V-----------------------GGLALWRQQLCAVAKV---------R
FLKLKSE-KRALLAILLLFGITFGPQLLEHLSYRLQQK-SYSWGLSPNTYFLSPGQPP--
QAPLTRLLVV-----NR--TGS-RIDDFIHSLRRQNIDLEVDALG----TRNG-PSEPSY
N-GAITVTGND-EDPR---FSIACNTKRLNCFP-VL-MDIISNGLLGMLN----------
----------SSEH--IQTDRSTYFEEHTS-------N-EHEYL-----GMAFFWIPGAA
CFTPYIAMGSIGDHKKKV-HSQLRISG-LYPSAYWFGQ-ALVDVPLY-------------
---FLILLLMQI---MDYVFNPDEF-----VFIIQNLA-VQTLCIIGYVSSLVLLTYVIS
FIFRHGRKNSGIWSFFFLVV-----TFFTIVANYL---NEYGF-LGLFLCTILIPPF---
--TLI--------GVQLIFSEIS----------PDS------VDYLGASEQQVAYLTLLI
PYLHFFIFLFILRCLE-MKFRKKPMRKDPVF-RISPRSSAVFANPEKPEG----EDEDVQ
TERRRTADAVA-APDAE--EKPAIVASCLRKEYAGRKKNCFAKRK--KKVATRNVSFCVK
KGEVIGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3038)
STTIKMITGDTRPTAGQVL-LA--GGSG-------GV----PPGF
LGYCPQESALWPGLTVREHLEVSAAVKGLQRADAA-----AAITR----LADALKLQDQM
ALPAKALPEGAK---RKLSFALSILGSPGLLLLDEPTTG----MDPEG-QLQTWQLIRAS
VRNTARGALLTTHSMAEAEAVCDRVAVMVSGSLR--------------------------
----------------------------CIGSIQHLKSK-FGRDYLLEMKLKSLARLEAL
HAEVLRIFPQAA--RQERFASL--VVYKLPVEDVHPLSHAFFSLETGESACCE-------
------------------------------------------------------------
---------------------------------------------------
ENSP00000284425 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLM-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTHMDEILLEN-----LPYAMGIIFNETF-SY----KLIFFQGYNSPLW-
---KE------DFSA----------------HCWDG---YG-EFSC-------TLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ITKNLLH--
NEMFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFVTI----------IITFTQIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILNICSPFAFTTGMIQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSMLLLDGLIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-RTNAKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHLKEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGITILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SMFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTENKEKLVYT--LPL
ER--TNTFPDLFSDLDKCSDQ---------GVTGY--DISMS----TLNEVFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAI
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKNELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLQMFN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLLMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFFIYMIS
FIFRKRRKNSGLWSFYFFFA-----STIMFSIT-LI--NHFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLEVRD----------QEHYREFPE---ANFELSATDFLVCFI
PYFQTLLFVFVLRCME-LKCGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDIQ
TERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTLREHLEVYAAVKGLRKADAR-----LAIAR----LVSAFKLHEQL
NVPVQKLTAGIT---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKETSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQTFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEIDT-TMRWKLLPHSDEP---------------------
ENSTGUP00000004190 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------QRNISVLQQIKILLWKNVMIKWR-----MKM
QSFQEWILS-LLFLPLVF--VVSSSPFMMK-ARLPEVPWA--HLGYLDDPAFNAT-GVTV
TFTPATA------TTRHIMNKVASSSLM------------------------------TG
IK--LVELDDERAMEKTWISN------RETIGVVFKDNF-SY----HLRFPTTHVVI-P-
---NE----VIGYVD----------------TCYN----FS-WSIC-------ESPRY--
WYKGFLSLQSSIDAAIIEMVANHSVWEEMESIAGVRMKSRSI---------LFSVSLE--
YSYFMMVIMMCFFPFMYFLSRNV-----------TREKKQLKELMKTMGLHDIA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWSLLY-SLYVLIFSCLLTA-----------LVLRERFYASSFPAVSLLFFLYG
LACIHLVLMLCS----------------------------LLRTSKIV---SCMG-----
FF-IIFIFGF--------LSLAVLIEDVPEPLKWFLGLMCPFAFNTAIAKIFDLEKY---
------RIGFSFSNLMGEAHFLFSTYILLVFDSVLYILLALYFDKILPGK---YGIPDPP
LFFLKASYWMRSRRG-SSRD-ETRAIENPEEL-LGDDVEPVPPEFLGKEAIRLHNIKKAY
-------------KKK------D-----------------------------KKTEAL--
--R--GLSLNIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNVLSGLSFPSA--GSATIYNYKLSEMGDR
EEIRG-MIGICPQF--NPHFEVLTVKE-NLKTFAEIKGIKSKEVE-REVQNILELLDISN
IQDTQAEKLSGGQKR-KLSIGIAMLGNPQV--LFLDEPTAGLDPLSRHRVWSVLREQ---
---------------RVGRVVLFSTQLMEEAD----------------------------
--------------------I---------------------------LADRKAFISHGR
LKCVGS--SLFLK---KKWGI---CYHL--RIHVS-E----------------------S
CDLENV-TSLVKGY--------------------IPNATF----SGHTHYELRYK--LPL
EN--VNKFPDLFSGLDSCSEQ---------GIINY--GVSMT----TLEDVFLRLEGE-A
MADQEDEP---------VR-GEE-WGA----------A--GSPEEAR----PGSLLLS--
----DTGTASV-----------------------QGLALWRQQVSAMARV---------H
FLKLKSS-VKNLRSILLLYVVFLLPLVLQLCMVAGWQS-VSAWQLSPARYFLPLGRRS-Y
-LETTTLLVY-----NH--TGT-DIDDFIHVLQSQDIAVEMAKEE----N---VTEELEH
N-GALLLSCSL-KSYR---FTVLCHLEAINCFP-VL-VNVISNALLRSLN----------
----------STRH--IQVWSHPFFSL-----------VNPGYWDYIMSFYLIYMLLLLP
GFPPHFAMGYTQDCKV-GARAQLRVSG-LFPSAYWCGQ-ALVDIPLC-------------
---WILLFSMLG---LQFAMSNK-------ISGNASVTLLLVTGMLGYGISLVLLIYLIS
FNSRKEW-SCDLWSFILIVV-----S--TWLVSRILNNLGR-L-TSLYTLSLLVPVY---
--PLM--------YFLLFLQ------------NLM-QDNESFGAASGSHVLIAVFA----
PYIHSVVFILLLRFLE-LKYGKAVLRQDPVF-RISPRKESSQQHPKELE----EEDEDVR
AEREAVRNAVV-APSQE--EKSAIIVSNLCKEYKIKKAGSLFKKK--KKTATKNLSFCVK
KGEVLGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STAIKMITGETTLTAGQVL-MK--RGDGG---GSLEQ----APVF
LGYCPQENPLWLDLTPQQHLRVYAAVKGLQQEDAA-----AAVHR----IVNALQLQDYL
NKKVRKLPAGIT---RKLCVALSLLGNPSVLLLDEPSTG----MDPNG-QRCVWKTIRDA
LTSKESGALLSTQYMEEAEAVCDRVAILVSGQL---------------------------
---------------------------RCIGSIQYLKNK-FGKGYLLEIKVKDAESTDAL
HAEILKIFPGAA--RQERCPSL--LVYKIPMKDALPLSQSFSKLEEAKRSCSLE---EYS
F-SLNTLTQV----------------------------------------------FLEL
CREQEKDNFD-LTLDG-TFDWKQLQQED-----------------------
ENSRNOP00000005665 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------MCDSLVG----TKMVKREINVWQQTWALLCKNLLRKKR-----LKR
D
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLWELLYT-AFILLCLS--LFF---ELHDVYEFSSLSDV--DLGRVDS--FNDS-TFAI
AYTPVTP------TTQEIMNRVSLVSYM----------------------------T--G
RE--ILAFPNKENMTEFISKH-----YDDAVGIIFSTAY-SY----HLKFMKGTRIPII-
---KE----HQDHTA----------------HCFRY---E-PAISC-------DLSAF--
WRHGFVALQAAINSAIIEVTTNHSVMEEMMSLTGKYIKIDSF---------IAQEGTT--
TDYFLFLCIIAFSPLTYYISAGV-----------TRERKKMKAFMTVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVIVFIVTLFLTF----------VVYSVQFVFMTGFMMIFSLFFFYG
LSLISLSFLMSV----------------------------LLKKSFLT---DLVV-----
FF-LTVSCGS--------LGFAALYRYLPVSLEWLLSLLSPFAFMLGMTQLLRLDYD---
------LESSG--HPTGNPNVVIATVFLLFFDGVFYLMLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPGE---YGRRHPP
LFFLKSSFWT-GQNPADRTV--LDNERDYE-F-PDDSFEPVSTDFHGKEVIRIRNLTKEY
-------------IQR------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTK--GWVTIHDNKLSEMTDL
ESISK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIQ--EVD-NEVQRVLLALEMKN
IQNTLVQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2363)
AGLDPFSRHRVWNLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISQGK
LRCAGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------IPDSKL----SAESEGKLNYI--LPL
ER--TNKFPDLYRDLERCPDL---------GIENY--GVSVT----TLTEVFLKLEGK-S
AID-S---------DIGET-EDV-QAGGT--------RGPGRLD-GE----QFVSLLN--
----EMSKT-K-----------------------GGMALWWQQLCAVTRL---------R
FLKLKYR-RKSIVILILILGIGLLHILSANVHRLVNQS-DYCWELSPHTYFLTPGQRP--
QMPLTNLLII-----NK--TGE
PF12698 // ENSGT00760000118965_1_Domain_4 (2363, 2683)
-KIDDFLHSLEQQNIALEVDAFG----TRNG-TEDSQY
N-GAIIVAGGE-KNYN---FTLACNTKRLNCFP-VL-VDIVSNALLGLFT----------
----------PSVH--IQTDRSSFPEDTG---YT--QF---YHL-----LYMFSWILLMA
CVPPYISMTSIDDYKNRA-QFQLWISG-LSPSAYWFGH-ALFEIPVY-------------
---SALILSVYI---AFYFSAPPES-----MITTRDLF-IQILYAGGYAMSVIFMMYVIS
FICRKGRKNSGIWSLCFYIV-----SFISLCLM-LF--KFFE
ENSGT00760000118965_1_Linker_4_5 (2683, 2873)
D-TFLFSSIALIPVV---
--TLV--------GCTLLHFQNH----------E-----FPEIS-LY-PERYYTYLFFLA
PFFHFLIFLFILRCLE-RKFGMKTMRMDPVF-RISSRSDRVFNNPEEPEG----EDEDVS
LERVRTANALT-SADFQ--EKPVIIASCLRKEYKGKKKCFVLKGK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISLCVR
KGEVVGLLGHNGAGKSTSIKMITGEIKPSAGQVQ-LK--GNST-------GD----TPEF
LGYCPQENALWQHMTVREHLEIFAAIKGMSKSDAA-----VAIAR----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FANTERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKEYLLEMKVKTPTQVEPL
NMEIMRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFE-EELDP-SVKWKLLPQEEA----------------------
MGP_CAROLIEiJ_P0030721 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVRQQTCALLQKNLLKKWR-----LKR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1541)
TLMEWVSS-LLLLLFLY--WYP---HGHEATDLSSVPTK--DLGRVDS--FRQS-GFVI
GYTPVTS------MTQQIMEKVAATPFV----------------------------A--D
KK--VLGLLDEENIKELAESH------AEVIRVIFSDTF-SY----HLKFQFGQRIPTS-
---RE----LRDHNA----------------HCDGL---Y-EDANC-------LIAIF--
WKEGFVALQAAINAAIIETTTNHSVMEELLSVSGKFMKIHPF---------VSQEGIL--
TDFFIFTCIISFSPITYYVSINV-----------ARERKRMRGLMMMMGLRDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFIMAISLAL----------VIKSVQFFILTSFMMVFSLFLLYG
LSMITLAFLMSV----------------------------LVRKSVLT---GLSV-----
FL-LTIFWGS--------LGFTALYRYLPASVEWTLSLFSPFAFTLGMAQLLRVDYD---
------LNSNAPPDPASGSNLIIATNFMLVFDAFLYLALM
ENSGT00760000118965_1_Linker_0_3 (1541, 1682)
MYFEKVLPNE---YGHQHSP
LFFLKSSFWLRTRKP-AHVI--LEDGIDPVPS-SDDSFEPVSPEFHGKESIRIRNISKEY
-------------KGK------P-----------------------------NKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDVYEGQITAVLGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEMADL
ENILR-IAGVCPQA--NVHFDFLTVRE-NLRLFAKIRGIPPQDVE-KEVQRVLLELEMKN
IQNILAQNLSGGQKR-KLTFGIAILGDSQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2366)
AGLDPFSRHRVWNLLKER---
---------------RADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGV---GYHL--SLQLK-E----------------------V
CVPGNI-TSLVKQH--------------------IPAAKL----SAEGEGKLLYT--LPL
ET--TYRFPELCQSLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-A
TIDEP---------EVDIV-GEG-QTERS--------GDTERLMEME----QTLSSLR--
----ETEK--T-----------------------GSMALWRQQTCAIAKV---------R
LLKLKHE-RKTLLSVLLILVVGICPLLFENITAKIRQS-SYTWELSPHDYFLAPGQQP--
QGMLTQLLII-----NK--TEA-SI
PF12698 // ENSGT00760000118965_1_Domain_4 (2366, 2766)
DDFIHSVERQNIALEVDASG----ARDG-TDDPSY
N-GALIVSGNE-KNHS---FSFACNTKRLNCFP-VL-MDILSNGLLGMVK----------
----------PSAR--IQTDRSTYLVDEI-----THPL---EGL-----GKTAFWLILTS
ACPPYIAMSSVTDYKNKA-WFQLRVSG-LFPSAYWVGQ-AMVDIPLY-------------
---CFVFLFMSL---MDYLLRFPDT-----MFSIISHV-IQIPCSVGYAISLIFLTYVIS
FISRKGKKNSGIWSLSFFII-----TVFSVAVM-LL--AFDVS-GTQYCFIFLIPPS---
--TLV--------GCLILSMHLF----------IY------RIFEGG--QIVEPFLVFLI
PFLHV
ENSGT00760000118965_1_Linker_4_5 (2766, 2873)
FIFIFTLRCLE-WKFGKKTMRKDPIF-RISPRNNDVYQNPEEPED----EDEDVQ
MERMRTANALV-STSFD--EKPVIIASCLRKEYAGKWKHCLSKKK--AKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEILGLLGHNGAGKSTSLKMISGDTKVTAGQVL-LK--GSRE-------GD----TPGF
LGYCPQENALWPNLTVKEHLEVFAAVRGLSKSHAA-----VAITR----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSILLLDEPSTG----LDPEG-QQQIWQAIRAI
IKNTDRGALLTTHYMAEAEALCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLEQVEPL
NTEVLRLFPQAS--RKERYSLL--MAYKLPVEAVQPLSQAFFKLEKVKQTFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFE-EELDS-SIKWKLLPQEEA----------------------
ENSODEP00000012139 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNRRHISVSQQVWTLLCKNCLKKWR-----TKR
ETLLEW
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
FFS-FLLLLFAF-LFSF---NLHQVHDFSQMPAM--DLGRVDH--FNDS-NYII
AFTPESK------NTQEIMNKVASAPFM------------------------------KG
RT--IMGWPDENSMMELDFND-----SIDAVRIIFNDMF-SY----HLKFSWGLRIPNI-
---KE----HKDHSA----------------HCQVV---D-GKLTC-------ENSVF--
WEKGFVALQAAINAAIIEVAVNHSVMETLMSITGVNMKILPF---------IAQGGTT--
TDFFIFFCIISFSAFIYYLSVNV-----------SNERQYMKSLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGSMY-SGFILVMAVLMAV----------IVKSTQIIVLTGFTVVFILFFLYG
LSLITLAFLMSV----------------------------LIKKPHLT---GLAI-----
FL-LIIFWGS--------LGFTALYRHLPVFLEWILCLLSPFAFTAGMAQIIHLDYD---
------VNSNVHLDASNNSYTIIATFFVLVFDSLLYLALTV
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YLDKILPTK---YGHRHSA
MFCLKSSFWCQNKKT-NHVA--LEDETDSDPS-SNDSFEPVSAEFHGKEAIRIQNLKKEY
------------K-GQ------R-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDIYEGQITALLGHSGAGKTTLLNLLSGLSTPTS--GSVTIYHHTLSEMADF
ETISK-LIGVCPQS--NVQFGFLTVRE-NLRLFANVKGILPQEVE-QEVQKILRELDMEN
IRDILAQNLSGGQQR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2390)
AGLDPLSRHHMWNLLKER---
---------------KADRVILFSTQLMDEAD----------------------------
--------------------I---------------------------LADRKVFISHGR
LKCAGS--SLFLK---KRWGI---GYHL--SLHLN-E----------------------T
CDRGSI-TSLVKQH--------------------IPDAKL----TAQSEEKLVYV--LPL
ER--TNKFPDLYRDLDGCPNR---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DVAMW-GQL-QSDGR--------KGMASPDEPD----HDLPSLH--
----GARRV-A-----------------------GGMALWRQQLCAVAKV---------R
FLNLKNE-RKSLLAMLLLWGVSFLPQLLEHILFELNQK-SYSWGLSPDTYFLSPGQIP--
QDPLTCLLII-----NK--TGS-SIENFIQSLRQQNIALEVDTFG----
PF12698 // ENSGT00760000118965_1_Domain_4 (2390, 2704)
TRNG-TEESSY
N-GAIIVSGDE-QDHR---FSIACNTKRLNCFP-VL-MDIISNGLLGIFN----------
----------STEH--IQTGRSTFFPENMP-------N-GYWSL-----STAFFWVPLAA
CFTPYIAMSSIDDTKRKI-HSQLWISG-LYPSAYWFGQ-ALVDAPLY-------------
---FLILLVMQI---MDYVFSPEEI-----IFIIQNLL-FQILCSVGYVSALIFLTYVIS
FIFRNGRKNSGLWSFFFLTV-----TIFTIFATDI---SEYSF-LGLFLCTILIPPF---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GSLSIFSEIS----------YDS------VDYLGAKESQIGFLALLI
PYVQFFIFLFILRCLE-GHCRKKLLRNDPVF-RITPRSNDVFPNPEEPEG----EDEDVH
KERIRTVNAVT-TLD----EKPVITASCLRKEYAGKKKKCFSRKK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVVGLLGHNGAGKSTMIKMITGDVKPNAGQVI-LK--RSSE-------GE----PLGF
LGYCPQENVLWPNLTVRQHLEAYAAVKGLKKRDAV-----VSITH----LVEALKLQDDL
KTPVKTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQIWQAIRAT
FRHRERGALLSTHYMAEAEAVCDRVAIVVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVRILAQVQPL
HEEILRLFPQAA--RQERFSSL--MVYKLPMEDVQPLSQTFSKLETVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SEEQERGDFD-EDQDP-SVRWTLLPPEEA----------------------
MGP_CAROLIEiJ_P0030723 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKREINVCQQTWALLCKNLLRKKR-----LKR
DTF
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEFLYT-ALILLSLT--LFL---QLHEVYDFSSLPDV--DLGRIDS--FNDS-TFMI
VYTPITP------TTQRIMDRVSLVSYM----------------------------T--G
RK--ILASPNEENMTELISMR-----FSDVVGVIFTNAY-SY----NLKFIKGARIPTI-
---KE----HQDHTA----------------HCHSY---G-EIISC-------GLSEF--
WRDGFVALQAAINAAIIEVTTNHSVMEEMMSLTGKYIKIDSF---------VGQEGTT--
TDCFLFFCIICFSPLTYYISAGV-----------TRERKKMKGLMAVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-GVIVFVVTLLLTT----------IVKLVQFVFLTGFMVIFSLFFFYG
LSLISLSFLMSV----------------------------LLKKSFLT---DLVV-----
FL-LTVSCGS--------LGFTALYRYLPVSLEWLLSLLSPFAFMLGMVQLLRLDYD---
------VNSNA--DPMGNPNEVIGTIFMLFFDGVFYLLLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPSK---SFQDKTY
WHACKSHFFLIDYSFYIQTA--LDNETDYA-F-SDHSFEPVSTEFHGKEAIRIRNLTKDY
-------------IQK------S-----------------------------KRTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDVYKGQITAILGHSGAGKSTLLNVLSGLCVPTK--GWVTIHNNKLSEMTDL
ENISK-LTGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIQAHEVD-NEVQRVLLELDMKN
TQNILVQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2377)
AGLDPFSRHRVWNLLKER---
---------------RADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------IPDSKL----SAESEGKLSYI--LPL
ER--TNKFPDLYRDLERCPDL---------GIENY--GVSIT----TLTEVFLKLEGK-S
SIDQS---------DIGMT-EDV-QAGGA--------RSPERFAEVE----QLVSLLN--
----GRCKM-K-----------------------GGMALWWQQLCAVTRL---------R
FLKLKHE-RKSIVILILILGIGLLHILSANIYRMVRQS-DYCWELAPHMYFLTPGQQP--
QLPLTNLLIV-----NK--TGA-KIDDFIHSLEQQN
PF12698 // ENSGT00760000118965_1_Domain_4 (2377, 2681)
IALEVDAFG----TRNG-TEDSQY
N-GAIILSGDE-KNYN---FTLACNTKRLNCFP-VL-VDIVSNGLLGLFA----------
----------PSAH--IQTDRSTFPEEND---HR--NF---DYV-----AYFFSWVLLMA
CVPPYISMTSIDDYKNRA-QFQLWISG-LSPSAYWFGQ-ALFEVPVY-------------
---CALILSIFI---AFYASAPPES-----KFTVGDLF-IQSLYVGGYAMSIIFMTYVIS
FIYRKGRKNSGLWSLCFYIV-----SFFSMCFM-LI--DY
ENSGT00760000118965_1_Linker_4_5 (2681, 2873)
FRD-TSLFGFIALVPPA---
--TLG--------GCTLLHFENR----------E-----FSEII-YE-PEREYSYLFFLA
PLLHFAIFVVILRCME-RKFGMKTMRMDPVF-RISPRSNRVFNNPEDPEG----EDEDVS
QERVWTANALT-STDFQ--EKPAIIASCLRKEYKGKKKCFVLKSK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVR
KGEVVGLLGHNGAGKSTSIKMITGETKPSAGQVL-LK--GSST-------GD----TPGF
LGYCPQENALWLNLTVREHLEIFAAIKGMRKSDAN-----VAIER----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIQAT
FANTERGALLTTHYMAEAEAVCDRVAIIVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKEYLLEMKVKTPSQVEPL
NSEIMRLFPQAA--RQERYSSL--MVYKLPREDVQPLSQAFFKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGFE-EELDP-SVKWKLLPQEEA----------------------
MGP_PahariEiJ_P0037457 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRLGQQMWALLCKNWLRKFR-----MRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLLEWLFS-LLLISFVY-QLSS---NLHQVHDAPEMSVV--DLGRVDN--FNDS-NYII
VFAPESE------ATHEIMNKMASAPFM------------------------------KG
RT--IVACPDEKTMNELDLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPKT-
---KE----HKDHSA----------------PCEPL---N-NKMIC-------ENSAF--
WEKGFVAFQAAINAGIIEMTTNHSVMEELMSVIGSNMKMPPF---------IAQGGVA--
TDFFIFFCVISFSSLIYYLSVNI-----------TQERQYMTTLMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILGVAILISL----------IVKSAQVVVLTGFMVVFLLFLFYG
LSLITLSFLMSV----------------------------LIKKPLLT---GLAV-----
FL-LTVFWGS--------LGFTALYKHLPAFVEWTLCFLSPFAFTTGMAQLIHLDYD---
------VNSNVNLNSPNNSYLIIATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKITLSK---YGHQRSP
LFFLKSSYWFKHRGA-SHVV--LENEIDSDPS-LNDALEPVSPEFQGKEAIRIKNLKKEY
------------S-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINTLSGLSPPTT--GSVTIYNQTVSEMDDS
DAVLT-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQQVLRDLEMET
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2448)
AGLDPLSRHRIWNLLKER---
---------------RLDRVTVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------A
CNPEGI-TSLVKKH--------------------IPDARL----TTQSEERLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIEDY--GVSMT----TLNEVFLKLEGK-S
LADEL---------DVGIC-GRL-QSDGA--------REVESLVELE----QVL-SLD--
----SSGSS-V-----------------------SGMALWRQQLCAVAKV---------R
FLKLKNE-RKSLMTVLLLFGISFVPQLLEHLIYKVYHK-SYSWGLSPSMYFLSPGQPP--
QDPLTHLLVI-----NK--TGS-NIDNFVHSLRQQGIALDLDALG----TRNG-TEEALY
N-GAITVLGEE-KDLR---FSVACNARRLNCFP-VL-MDIISNGLLG
PF12698 // ENSGT00760000118965_1_Domain_4 (2448, 2771)
IFN----------
----------SSER--IQTDRSTVFEEHML-------Y-EYGFM-----SNAFFWIPVAA
SLTPYIAMGSISDHKKKV-LSQLWTSG-LYPSAYWCGQ-ALVDIPIY-------------
---FLILLLMQI---MDSIFSSEEF-----ISVIELLL-IQIPCSIGYASSLIFMTYVIS
FIFRNGRKNSGIWSFFFLIV-----TIFFIVATDI---NEYGF-LELLICTFLVPPF---
--TLI--------GSLLIFSEVS----------YDS------VDYLGASESQLVFLALLI
PYLHFLLFFF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-RCLRKKSLRVDPVF-RISPRSCHAFPNPEEPGE----EDEDVQ
MERVRTTGAMA-TLQTD--EKPVIIASCLRKEYPGRTRRCFSKTK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTIPTAGQVF-LK--GSGG-------GS----ALGF
LGYCPQENVLWPNLTVKEHLELYAAVKGQKKKDAV-----VTITR----LVNALKLQDHL
QALVKTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPSQVEPL
NTEIMRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSEAFFKLERLKEDFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFE-EEANS-SVKWKLLPQEEL----------------------
ENSMNEP00000001017 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAI---N-EKMKC-------ESSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQEKQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHMLSGMADV
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRYSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVFSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLWISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------ED----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSGGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFDP-SVRWKLIPQEEP----------------------
ENSOCUP00000012374 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIMKQKSVYHQTRALLQKNFLNKWR-----MRR
ESSLEWGIP-MLLGLYMG--IFS---YLKFNVHVPEMPPK--DLGRVDK--FNSSSLM-V
VYTPISS------ITQQIMNKTALSPSL------------------------------KG
VK--VIEAPNEKHVDEVLEHN-----IPFAVGIIFNDAF-SY----KLKFIDVYQIPLL-
---KQ-----EIFSA----------------HCFNG---YL-ENTC-------SLTKY--
WTRGFVTLQTTLNAAIIEITTNQSVMEELMSVTATNMKTLPF---------ISKDILQ--
NELFIFFTLLYFSPFIYFVSVNV-----------TKERKKYKDLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFISSIFITV----------IITSNQIVVMTGFMVIFTLFFLYG
VSLVALAFLLSV----------------------------LLKKAALT---NLIG-----
FL-LTLFWGC--------VGFTVYYKQLPSSLEWILSICSPFAFTAGMSQIIHLDFT---
------MNGVIFPDPSGDSYKMIATYSVLAFDGLIYLVLALYLDKILPYG---KERHYSP
LFFLNFLSRFQHQ-RTDNKI--IEKEIDPEHL-SNDCFESVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
--K--GLFFDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLNILNGLSVPTQ--GSVTIYNKNVSEMQDL
EEIRK-KTGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQKVE-QEVQRILLELDMKD
IKDNLAKDLSEGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHRVWSILKER---
---------------RADHVIIFSTQLMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGG
LKCAGS--SVFLK---RKWGL---GYHL--SLYKN-E----------------------I
CDPEQI-TSIINHH--------------------IPDAKL----KTENNEKLVYT--LPL
ER--TNKFPDLFSDLDKCSGQ---------GIMSY--DISMS----TLNEVFMKLEGK-S
AIKQD----------------FK-QTETI--------RGSESLNEME----TTPSFLP--
----EIQKT-V-----------------------SDMGLWRMQVCAIAWL---------H
FLKFKRG-RKLLLTLLLILGIAIFPLIMETILFYITNQ-KSDWEFKTESYFLSPGQLP--
QDPRTSLLII-----NK--TES-NIEDFVQSLKHQNILLEVDDFG----NRNG-TDALSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRVHCYP-IL-MNIISNGLLRMLN----------
----------HQQY--IRIERSTFPFEIL-------------FAWTGLAEGSVFLIFIAC
SISPYIAMSSVSDDKKKA-KSQLWISG-LYPSAYWCGQ-ALLDVNLL-------------
---IFILLSVFL---IVYIVNK---AHI---FISTQIVFALVAFVFGYGASLVFLTYVIS
FIFRKRGKYSGLWSFCFYIV-----FTMTLSII-SV--YHLYI-TEIITSMILFPPA---
--TLC--------GFLVFLVKIS----------HEFYNENND---SDFELTEVYLLVCLI
PYFQALIFIFVLRCME-LKCGKKVIQMDPIF-RIFPQSRDARPNPEETVD----EDEDVQ
AERLRTAAALT-TSKSD--EKPVILASCLHKEYEGQKKNCCSRRK--KKIAVRNISFCVK
KGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSIRMISGITKPTAGEVE-LK--GCTSV-GSHQGE----GMVKF
LGYCPQENVLWPFLTLKEHLELYAAVKGLKRGDAA-----IAIYR----LVSAFNLHEQL
NVPVQKLTAGIT---RKLCFVLSILGDSPVLLLDEPSTG----MDPTG-QQQMWQAIQAA
VKNTEKGILLTTHYLAEAEALCDRLAIMVSGRL---------------------------
---------------------------RCIGSVEHLKRK-FGQDYILKVKVKEPSQVMLV
HKEIVKLFPQAA--QQERCSSL--LTYKLPTADIYPLSQAFHKLETVKHNFTLE---DYS
L-SQCTLEKV----------------------------------------------FTEL
SKEQELGDVD-EEVDT-TMRWKLLSHLDEP---------------------
ENSDNOP00000029848 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------M----VKMNKRHISMGQQTWALLCKNFIKKWR-----MKR
QTLLEWFFS-LLL-PFAY-LSSS---NLHQVNDFSHMPAT--DLGRVDN--FNDS-DYVI
AFAPESK------TTQEIMNKVASAPFM------------------------------KG
RT--IMGLRNEESMDELDLNY-----SIDAVKVIFNDTF-SY----HLKFSWGHRIPKM-
---KD----HRDHSA----------------HCRAK---D-GEITC-------ESSKF--
WEKGFVAFQAAINAAIIEITTNHSVMEQLMSVTGINMKILPF---------VAQRGVA--
TDFFIFFCIISFSSFIYHLSINV-----------TQERQYIKALMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFVFIMSILMAI----------IVKSTQVVVLTGSVVVFILFFFYG
MSLITLAFLMSV----------------------------LIKKPFLT---GLVI-----
FL-LIVFWGS--------LGFAALYRHLPAFLEWTLCLLSPFAFTAGMAQLIHLDYD---
------VNSNVLLDSSNNSSLITATLFMLVFDALLYLLLTLYFDTILPTE---YGHRRSP
WFFLKSCFWFQRQNV-DHMA--LENEIDSDPS-LNDSFEPVSPEFLGKEAIRIKNLKKEY
------------K-GK------H-----------------------------EKVEAL--
--K--GLVFDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNVLSGLSVPTS--GSVTIYNHTVSKMADL
ENISK-LIGFCPQS--NVQFDFLTVRE-NLRLFAKIRGIQPQEVD-QEVQQVLLDLEMEN
IQDLLAQNLSGGQKR-KLTFGISILGDPQV--LLLDEPTAGLDPLSRHKIWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADKKVFISSGR
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CDPENI-MSLIKQH--------------------IPEAKL----TAQREENLVYI--LPL
ER--TNKFPDLYRDLDRCSNL---------GIENY--DVSMT----TLSEVFLKLEGK-S
VLDES---------DTGIW-GQV-QSDGA--------KDIGNLAELE----QVLSPLN--
----EASKT-I-----------------------SNMALWRLQLGAIAKV---------R
FLKLKKE-RKSLMLMLLLFGISFFLHLSECLYFELYSK-SYAWGLSPNIYFLSPGQPP--
QDPLTPLLII-----NK--TGS-SIDDFIRSLKRQNIALEVDDFG----TRNG-TDDPSY
N-GAIIVSGTE-KDLR---FSVTCNTKRLNCFP-VL-MDIISNGLLGVFN----------
----------SSEH--IQTDRSTYFEEHIS-------C-ESGYL-----SNALFWIPVAA
CFTPYIAMSSIGDYKKKI-HSQLRISG-LYPSAYWFGQ-ALVDGPVY-------------
---FLILLLIQI---MDYIFSPDEI-----IFIIQNLS-IEILCSIGYVSSLIFLTYVIS
FIFRNERKNSGIWSFFFLTI-----AIIAIAANEL---NRYGF-PGLFLCTVLLPPF---
--TLT--------GSLFIYFEIS----------PDF------MDYLGSAESAIVYLALLI
PYLQFFIFLFILRCLE-MKFRKKSMRKDPVF-RISPRSTDIFPNPEQPEG----EDEDVQ
AERVRTANAMT-TPEFD--EKPVVIASCLLKEYAGKKKNCFSKRR--KKMATRNVSFCVR
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTIKMITGDTIPTAGQVL-LK--GSSG-------GE----AVGF
LGYCPQENALWPSLTAREHLEVFAAVKGLRGAAAQ-----AAIAR----LVEALQLQDQL
KVPAKALSEGLK---RKLCFALSVLGSPAVVLLDEPSTG----MDPEG-QQQMWQAIQAT
IRNTERGALLTTHYMAEAEAVCDRVAVMVSGRLR--------------------------
----------------------------CMGSIQHLKSK-FGKDYLLEMKVKTLENWEAL
HAEILRLFPQAA--HQERFSSL--MVYKLPVGDVKPLSQAFLKLETVKLNFDLE---EYS
L-SQTTLEQV----------------------------------------------FLEL
SKEQELEDFE-EELDP-SVKWKLLPQQES----------------------
ENSMUSP00000035458 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MKELSVHVRQQTRALLHKILLKKWR-----RKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWSIP-IIIGLHMG--LFS---YLARNIQVLEVPPQ--DLGSLNE--FNGSSLV-V
VYTPISN------ITQQIMNKTTFAPTM------------------------------KG
TR--IIGVPSIEDLDEVLLHN-----IPDALGVIFNDSF-SY----QLKVLRMYGNPFL-
---K------EDLLA----------------HCWDT---HS-QAFC-------SLSKY--
WERGFVALQTAINAGIIEVTTNHSVMEELMSIDGINMKTLPF---------IPRDLSD--
YEIFILFCLLYFSSFIYFASSNV-----------TKERKQCKEVMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIISIFIAI----------IITSTQIIMMTGFLVIFTLFFLYG
LSLIAVTFLMAV----------------------------LLQKAVLT---NLIV-----
LF-FTLFWGC--------VGFTVLHKELPPSLEWVLSIFSPFAFTSGMAKVIFQDYN---
------LNGVVFPDPSGESYVMIAVFFILAFDSLLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---AEHRSAP
LFFLNPTSCFR-KTANRNKV--IERDLDPELP-SDEYFEPVDPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVKAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA--GSVTVYNKNLSDMQDL
KEIRK-AIGVCPQH--NVQFDALTVKE-NLTLFAKIKGILPQDVE-QEVQQILSELDMQN
IRDDLAEHLSEGQKR-KLTFGIATVGDPQI--LLLDEPTVGLDPFSRQRIWGFLKER---
---------------RADHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVLIANGA
LKCTGS--SVFLK---RKWGL---GYHL--SLFMD-E----------------------T
CDSERL-TSFINHH--------------------IPYAKL----KAKTKEKLVYI--LPL
ER--TSEFPEFFSDLDKYSGQ---------GLMSY--EVSMS----TLNDVFLNLEGE-P
STKQD----------------FE-KRETA--------TDSESLNDME----VAYPSLS--
----QVQET-V-----------------------STMSLWRMQVCAIARL---------R
ILKLKRE-RKAFLIILLLLGIALLPLVIEYVANALLEV-KNNWEFKTDLYFLSPGQLP--
QGLRTSLLVI-----NN--TES-NIEDFLQSLKHQNIVLEVDDFE----NRNA-TNSLSY
N-GAIIVSGRQ-KDYR---FSAVCNTKRLHCFP-IL-MNVISNGILHMLN----------
----------HTQY--IRIKEDIFSPFIV-------------LVWTGIQETCLFILCVIC
SLSPHIAMSSVSDYKKKA-DSQLWISG-LYPSAYWCGQ-AVVDISLF-------------
---SGMLLTSYF---TSYTSKL---LNI---DMTSEIVFSVIVLALGCAASLVFLTYVIS
FVFGKRKKNSTLWSICFLLV-----IAITFEKV-AN--GPFNE-ALVISATMLVPSF---
--ALN--------GLLVVLEMRA----------YQYYIEFEE---IKHGLSAVDLLLCLI
PYIHTLLFIFVLRCLE-LKYGKNVVRRDPIF-RIAPQSLKAQPNPEEPID----EDENVQ
AERLRTSDALS-TPNLD--EKPVIIASCLHKEYAGQKKHCCSRRT--RNMAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVN
KGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE-LK--RLSSA-VGHQGDS-----RAE
FGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAV-----VAISR----LVNALKLHDQL
NVQVQNLVAGAT---RKLCFVLSILGNSPVLILDEPSTG----LDVSG-KHQVWQAIQAV
VKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL---------------------------
---------------------------RCIGPIQHLKRK-FGQDYVLELRVKDVSQEPLV
HREILKLFPQAA--RQDRCFSL--LTYKLPVTDVHPLSQAFHKLEAVKHGFDLE---DYS
L-SQCTLDRV----------------------------------------------ILEL
SKEQELGTVY-EEADM-TLGRKLLPPSDEL---------------------
ENSCHOP00000008317 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----EWGLP-ILLGLYMG--LFS---YFRENFRVPEMPPQ--DLGRVDK--FNTS-SIKV
VYTPISS------ITQQIMNKTALAPFL------------------------------KX
XX--XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX-XX----XXXXXXXXXXXXX-
---XX-----XXXXXXXXXXX-----XX---XXXXX---XX-XXXX-------XXXXX--
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXX--
XXXXXX-X----XX-XXXXXXXX-----------XXXXXXXXXXXXXXXXXXXX------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---X---XXXXX-XXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXX
XXXIALVFLVSI----------------------------LLKKTVFT---SLVV-----
FL-FTFFWGC--------VGLTVLHRQLPSALEWILSICSPFAFTAGWAQIIHLEIN---
------LNGVIFPDPSGDSYIMIATFFMLAFDALLYMVLALYFDRILPYG---SEHRYSP
LFFLNSSSCFQHQRI-HNKI--TEKEIDSEHP-YSDYFEPVDPEFQGKEAIRIRNVRKEY
-------------KGK------S-----------------------------EKVEAL--
--K--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXX
XXXXX-XXXXXXXX--XXXXXXXXXXX-XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXL--LLLDEPTAGLDPFSRHRVWNF-KER---
---------------KANHVILFSTKFPDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SLFLK---RKWGL---GYHL--ILCRN-E----------------------L
CDPE---TSFINHH--------------------VPDAKL--X-XXXXX-XXXXX--XXX
XX--XXXXXXLFSDLDKCFSQ---------GVMSY--DVSMS----TLNEVFMKLEGK-S
TFEQXXXX--------------X-XX--X--------XXXXXXXXXX----XXXXXXX--
----XXXX-XX-----------------------XXXXXXXXXXXXXXXX---------X
XLKLR-G-KK--ALLLLVLAIAVLPLIVEKIFSAILSQ-KNDWEFKPEFYFLSPGQRS--
RDSHTSLLII-----NNTES---YIENFICSLIRHYII-LVNDFE----NRNG-TDDLSY
D-GPIIVSGLK-XXXX---XXXXXXXXXXXXXX-XX-XXXXXX-----------------
-----------XXX--XXXXXXXXXXXXXX------XXXRYMMFLTGLPEGTVFLYLIVS
SISPYIAMSSVSDYKN-KAQFQLWISG-LYPSAYWCGQ-ALVDLNLY-------------
---AFILLSTYS---VVLLGDVLPI------HVTSRIVFAMVVFAFGYAASLIFLTYVIS
FVFSNRRKNSGLWSFCFYVI-----SSFI--FSLILM-NDLNI-SVSVTCMALVPMS---
--TM--------GGFLTFLIEX-----------XXXX--XXXXXXXXXXXXXXXXXXXXX
PYFQALIFIFVLRWLE-IKYGKKTMRKDPVF-XXXXXXXXXXXXXXXXX----XXXXXXX
XXXXXXXXXXX-XXXXX--XKPVIIASCLHKEYASKNKICCSKRK--KKVAARNISFCVK
KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX--XXXXXX-------------XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX----LVDTFKLHGQL
KVPVQKLTAGVT---
PF00005 // ENSGT00760000118965_1_Domain_6 (3016, 3091)
RKLCFVLSMLGNSPVLLLDEPSSG----MDPAG-RQQMCQAIQTA
IKNTTRGALLITHHLAEAEILCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FVKDYILELKMKETSQGPLV
HAEILKLFPQAA--RQERYSYF--LVYKLPMADVHPLSQAFQKLEAVKHDLNLE---EYS
L-SQCTLEK---------------------------------------------------
---------------------------------------------------
ENSFCAP00000014540 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYHQTQALLHKNFLKKWR-----MKR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
SLLEWIFP-ILLGLYLG--LFS---HFREKTYFPEIPPQ--ALGRADN--FNNS-IG-V
VYTPVSD------ITQQIVNKTTFAPFV------------------------------KE
RR--LIGVPNQKSMDKLLLDS-----FADLVGIIFNDAF-SY----KLKFVQGYNIPFL-
---KE-----DLFTA----------------HCWNM---HG-DFSC-------SLAKY--
WNRGFVTLQTAIDAAIIQIATNRSVTEELMSVTAINMKTLPF---------IHKNILQ--
KEMFIFYCLLYFFPLIHFISLNV-----------TKERKKWKDLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIIITA----------VITSTQIIVMTGFMVICTLFFLYG
LSLIALVFLMSV----------------------------LLKKTVLT---NLVM-----
FL-LIVFWGG--------VGFAAYYRQLPSSLEWILSICSPFTFTAGLSKIIHLDST---
------MNGVIFPDPSGDSYVLIATFSVLAFDALFYLALAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPCG---NERHYSP
LFFLNS-SCFQHQ-RTNNKV--TEKEIDPEHP-SDDCFEPVAPEFQGKEAIRIKNVKKEY
-------------TGK------S-----------------------------GKTEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLLLDIYEGQITAILGHNGAGKSSLLNILNGSSVPTE--GSVTIYNKNPSETQDL
EEIRK-MTGVCPQF--NVQFDILTVKE-NLRLFAKIKGIRPQEVE-QEVQRILLELDIQN
IQDNLAEHLSEGQKR-KLTFGIAILGDPQI--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2303)
AGLDPFSRHRMWSFLKEH---
---------------KAGRVILLSTNLMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---RKWGL---GYHL--SLYRN-E----------------------I
CDPEKI-TSFINHY--------------------IPDAKL----KTENKEKLVYT--LPV
ER--TNKFPDLFSDLDKCCDQ---------GVMSY--DVSTS----TLSDVFMKLEGK-P
TIEQD----------------FE-QAEVI--------RDTESLHDIE----PAWSSLP--
----ETRKN-M-----------------------SDLGLWKMQICAIARL---------R
FLKLKHG-KKELLTLLLVFGIA
PF12698 // ENSGT00760000118965_1_Domain_4 (2303, 2720)
VFPLVVEKILYAILFQ-KSDWEFKPELYFLSPGQPP--
EDPRTSLLII-----NN--TES-NIEDFIQSLKHQNILLEVDDFA----NRNG-TGDLSY
N-GAIIVSGKQ-KDYR---FSVVCNTLRLHCFP-IL-VNIVSNGLLRMFN----------
----------STQN--IRIERSPYPFNYV-------------LFWIGLPEGSMFLFWVVC
SMSPYISMSSVSDYKRRA-KSQLWISG-LYPSAYWCGQ-ALVDISLF-------------
---VFLLLSMYL---IFYIANI---TSI---YVTSRIVFALAVITLGYAASLVFLTYVIS
FIFRKRRKNSGLWSFCFFIT-----STIMFDTL-VM--NHFNL-PVLISSMILIPSS---
--TMG--------EFLAFL
ENSGT00760000118965_1_Linker_4_5 (2720, 2873)
AERA----------QAYHSDNQD---RHFDLSGVDLLVCLI
PYFQTLILVFLLRCME-AKWGKKITRRDPVF-RISPQSRGAQPNPEEPGD----EDEDVK
AERIRTATALA-TSLSE--EKPVIIASRLHKEYAGQKKSCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEILGLLGPNGAGKSSSIRMISGIAKPTAGEVE-LR------G-WGHQGDS----MVGF
LGYCPQENVLWPCLTVREHLEVFTAIKGLRKGDAT-----VAISR----LVDTFTLREQL
NVPVQKLTAGAT---RKLCFVLSILGNSPILLLDEPSTG----MDPGG-QQQMWQMIQAA
IKNTEKGALLTTHYLAEAEAICDRIAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYVLELKVKESSQVTWV
QAEILKLFPQAA--QQERCSSF--LAYKIPLADVYPLSQTFHKLEAVKHKFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELGNFE-EEIDT-TMRWELLSPSDDP---------------------
ENSOGAP00000001100 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MDLKQKSVFQQTRALLHKNFLKKWR-----MKR
ESSLELGFS-ILLGVFLD--MFS---NLLKSGQSPELPSF--DLGRADK--FNSSSRM-V
VYTPISS------ATQEIMNKTFL--LL------------------------------KE
KS--VIGVPSEKHMDKILEEH------YYAVGIIFNDIF-SY----KLKFIQGYEIPFV-
---SE-----DYQSV----------------PCWVG---YE-EFSC-------MLNLY--
WTRGFITLQTAINAAIIEVTTNHSVIENLMSVTARTMKTLAF---------VYRDVVQ--
DELFVLFCLLYFCPLIYFVSLNV-----------TKERKKYKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGIIY-AGLFFVISIIIAV----------IITSTQIIIMAGFMIIFTLFFLYG
LSLIALVFLVNV----------------------------LVRKAVLT---SLVV-----
FL-LTLFWGG--------LGFPAIYKHLPSSLEWIFSICSPFAFTAGMTKVTQMDHN---
------VSGEIFPDSSGASNTMIATVFILALDGLLYFLLTLYFDKNLSCE---SERRCAP
LFFLNSSSCFHHQ-RTDNKV--IEKEVDPELP-SDDYFEPVAPEFRGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
--K--DLLFDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
KEIRK-IIGICPQF--NIQFDVLTVKE-NLSLFAKIKGIHSQEVE-QEVQRILLELDMQN
IQDKVTEHLSEGQKR-KLTFGIAILGDPQV--LLLDEPTTGLDPFSRHQVWSFLKER---
---------------RANRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SSFLK---RKWGL---GYHL--SLYRN-E----------------------T
CDPEQI-TSLINHH--------------------VPDAKL----KMESKESLVYM--LPL
ER--TNTFPDLFSDLDKYSTQ---------GVMGY--DVSTS----TMDEVFMKLEGK-S
TIEPD----------------FE-QVEMA--------RDSESLDEME----QTHSSLP--
----EPRKA-A-----------------------EGMGLWRMQVWAVAWL---------R
FLKLKRE-RKGFLILLLIFGIAAFPLIVENILFVVFDE-NFEWEFKTGLYFLSPGQLP--
QEPRTSLLVI-----NN--TES-NIEDFIQSLKHQSILLEVDDFK----NRNV-SEGFSY
S-GAIIVSGKQ-KDYN---FSVVCNTRRVHCFP-IL-LNIISNGLLRMFN----------
----------QTNH--IRIERSPHPFNSA-------------LYWSTLPEGSIFLFLVIC
STSPYVAMSSISDYKKKT-KSQLWISG-LYTSAYWCGQ-ALVDIGFF-------------
---LLLLLLIYL---IFYMENL---EYV---YVTTRITCAMVIITPGYAASLIFLTYMIS
FIFRKRKKNSGVLSFCFFVV-----SCIVLNII-LT--HHFGL-GTIISTLVLVPSF---
--TLF--------GFLSLIQERS----------HEHYVTFQE---SNFDLNEADLLVCLI
PYFQALLFIFVLRCME-LKWGKRRTRKDPVF-RLSPQSREARPNPEEPID----EDEDVQ
AERIRTTTALT-TSNLD--ETSVIIASCLHKEYAGQKKNCFSKRK--KKIATRNISFCVE
KGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSIRMISGITKPTTGEVE-LK--GCSSI-SSHQGE----GPVKF
LGYCPQENALWPMLTVREHLEMYATVKGLKKGDAN-----VAITR----LVDAFKLHEQL
NVPVQKLTAGAA---RKLCFVLSILGNSPILLLDEPSTG----MDPTG-QQQMWQAIRAA
VKHTESSVILITHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYILEIKVKETSQVTLV
HTEILKLFPQAV--QRERYSSL--LTYKLCLADVYPLSQAFHKLETAKCKFNLE---EYS
L-SQCTLEKI----------------------------------------------FLEL
SKEQEEENFD-EEVDT-TMRWRLLPHSDEP---------------------
ENSOCUP00000006930 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKREISVCQQTWALLWKNLLNKKR-----MKR
NTFMECFYS-LLILLMLY--VFP---NSHEINDFSSLSTV--DLGRIDS--FNDS-SYVV
AYTPFTN------TTQRIMSKFSSASFM----------------------------T--G
RE--VMALPDEENITEIISHH-----YGDVVEVIFTNTH-SY----NLKFMRGYRMPNM-
---KE----HQDHLA----------------HCHKT---E-DMIVC-------EATYF--
WTKGFVAFQAAINAAIIEITTNHSVMEELMSVTGKYMKIDLF---------ISQGGIL--
TDFYILTCIICFSPLTYYASLGV-----------TRERKKMKGFMTMMGLRNLA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGVLY-AGYVFILALCLTF----------IIKSVQFVILPNFMVVFLLFLFYG
LSLIALTFLMSV----------------------------LVKKSFLT---GLVV-----
FL-LTVVWGS--------LGFTALYRQLPASLEWILSLFSPFAFTLGMTQLLHMDYD---
------LNSNA--DSMSDSNIIILTIFMLFFDSFLYLTLMFYFEKILPNE---YGRRRSP
LFFLKCSFSSQQNTA-DHEV--LENEIEYD-S-SNDSFEPISPEFHGKEAIRIRNITKEY
-------------IGK------P-----------------------------KR
PF03193 // ENSGT00760000118965_1_Domain_2 (1675, 1716)
IEAL--
--K--DLVFDIYEGQITAILGHSGAGKSTLINILNGLCVPTK--GSITIYNHKLSEMDDLENIYK-LIGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIHPHEVD-NEVKRVLLELEMKNIQDILAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPLSRHRVWSFLKER------------------KTDHVILFSTQFMDEAD------------------------------------------------I---------------------------LADRKVFLSKGKLKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------TCAPERI-TSLIKQH--------------------IPEAKL----LAESEGKLICT--LPLER--TNKFPDLYKDLENCPDL---------GIESY--GVSMT----TLNEVFLKLEGK-SAFDQS---------DMNVL-----ETDGT--------RDTGRLAEME----QLVSSLN------EMRKT-T-----------------------GGMALWLQQVYAIARV---------RFLNLKHE-RKCLLILILTVGAGILHVLAANARKILRQD-DYCWEISPHLYFLAPGQEP--HGPFTNLLII-----NK--TGK-SIDDFIRSVAQQNIALEVDAFG----TRNG-TDDSSYN-GAIIVSGDE-KNYR---FSLACNIKRLNCFP-VL-VDIVSNGLLGMYT--------------------PSAH--IQTDRSTFPEENA----Q-EQL---ESV-----AFLISWLLLMCSFPPYISMTSNNDFKNKA-QSQLWVSG-LYPSAYWFGQ-TLVEVPIY----------------FSLIIFMYI---VYYILKLQEG-----IFKAEDLF-IQTLYVVGYAISLTFLTYVISFIFRKGRKNSGIWSFCFFLI-----TLFSTFFM-LI--NGLEN-ALLFYISTLIPSA-----TLI--------GCTVLHYVYR----------T-----YYDII-SEGYGMELTFLVFLAPFLHFIIFVFILRCLE-CKLGKKTMRKDPIF-RISPRSSEAHQNPENLEG----EDEDVQMERARTANALT-SPNLE--EKPVIIASCLRKEYAYKK-KCFSKKK--KKIATRNISFCVRKGEILGLLGHNGAGKSTSIKMITGDTKPSAGQVL-LK--GSSR-------GD----TLGFLGYCPQEDALWPSLTVRQHLEVFAAVKGLKKAEAN-----IAISR----LADALKLQDQLKAPVKTYLRE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLINILNGLCVPTK--GSITIYNHKLSEMDDL
ENIYK-LIGVCPQC--NVQFDFLTVRE-NLRLFAKIKGIHPHEVD-NEVKRVLLELEMKN
IQDILAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2495)
AGLDPLSRHRVWSFLKER---
---------------KTDHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------T
CAPERI-TSLIKQH--------------------IPEAKL----LAESEGKLICT--LPL
ER--TNKFPDLYKDLENCPDL---------GIESY--GVSMT----TLNEVFLKLEGK-S
AFDQS---------DMNVL-----ETDGT--------RDTGRLAEME----QLVSSLN--
----EMRKT-T-----------------------GGMALWLQQVYAIARV---------R
FLNLKHE-RKCLLILILTVGAGILHVLAANARKILRQD-DYCWEISPHLYFLAPGQEP--
HGPFTNLLII-----NK--TGK-SIDDFIRSVAQQNIALEVDAFG----TRNG-TDDSSY
N-GAIIVSGDE-KNYR---FSLACNIKRLNCFP-VL-VDIVSNGLLGMYT----------
----------PSAH--IQTDRSTFPEENA----Q
PF01061 // ENSGT00760000118965_1_Domain_4 (2495, 2697)
-EQL---ESV-----AFLISWLLLMC
SFPPYISMTSNNDFKNKA-QSQLWVSG-LYPSAYWFGQ-TLVEVPIY-------------
---FSLIIFMYI---VYYILKLQEG-----IFKAEDLF-IQTLYVVGYAISLTFLTYVIS
FIFRKGRKNSGIWSFCFFLI-----TLFSTFFM-LI--NGLEN-ALLFYISTLIPSA---
--TLI--------GCTVLHYVYR----------T-----YYDII-SEGYGMELTFLVFLA
PFLHFIIFVFILRCLE-CKLGKKTMRKDPIF-RISPRSSEAHQNPENLEG----EDEDVQ
MERARTANALT-SPNLE--EKPVIIASCLRKEYAYKK-KCFSKKK--KKIATRNISFCVR
KGEILGLLGHNGAGKSTSIKMITGDTKPSAGQVL-LK--GSSR-------GD----TLGF
LGYCPQEDALWPSLTVRQHLEVFAAVKGLKKAEAN-----IAISR----LADALKLQDQL
KAPVKTYLRE--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSPVAP00000011485 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDKMALASCM------------------------------KG
RT--IIGTPDEETMDTVLPQS-----HFDMVGIVFNNTF-SY----KLKLSWEYRIQMI-
---KE----HFQYSE----------------HCWAL---QDGI-YC-------SLTTY--
WQRGFAAFQAAINAAIIEVTTNHSVMEELTSVIGINMRTLPF---------ISRGETV--
NEWFIFICIVYFSPFIYFASLNV-----------TKERKQFKKLMMVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FXXXXXXXXXXXXXXSVSIFMAL----------VITSIQIIIITGFMVIFTLFILYG
LSLVALAFLLSV----------------------------LIKKPVLT---GLVG-----
FL-FTVFWGC--------LGFTALYQQLPSSLEWILGLFSPFAFSAGMAQITHLDYY---
------LNGVIFPDPSGESYVMILTFFLLAFDTLLYLILTLYFERVLPDE---DGHWHSP
LFFLKSSFWSRHQ-NTHHED--FEDEISPEHS-SDDSFEPVSPEFHGKEAIRIRNIKKEY
-------------NGK------P-----------------------------EKVEAL--
--Q--GIYLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQVTAILGHSGAGKSTLLNILSGFSVSTE--GSAAIYNTTLSEITKM
EEIRK-KVGFCPQC--NIQFEFLTVRE-NLRLFAKIKGIQPKEVE-QEVKRVIMELDIQN
IQGVLAKKLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWNLLRER---
---------------KTNHMILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CNPERI-TSLIRQH--------------------ISDAKL----TAKSEEKLVYS--LPL
ER--TNRFSDLYNDLDKCSDQ---------GIMNY--GVSMT----TLNEVFLNLEGN-S
AIEEP-----X--XXXXXX-XXX-XXXXX--------XXXXXXXXXX----XXXXXXX--
----XXX---X-----------------------XXXXXXXXXXXXXXXX---------X
XXXXXXX-XXXXXXXLLVLVIAFIPTIFEKIMQMIIYQ-IHPWELSSSMYFLSLEQLP--
HTPLTSLLVI-----NN--TDS-DIEDFIQSLKHQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKRMNCFP-VL-MGIVSNALLGIFN----------
----------YTEL--IKTERSTFPVDDL-------------VLRHGFLGVPLLMLLFAN
CISPYIGMSSISDYKLKA-QSQLWISG-LCPSAYWCGQ-ALVDIPLY-------------
---SLILLSIYL---IYCFMVF----EL---RLSLGLIFALVVGIIGCAGSLIFLTYLIS
FIFRKWRKNNGFWSLSFFIF-----SILAVIIL-LL--TFSGD-SSLILSMILMPFY---
--TLV--------GFIIFVIQLD----------VL--RSPKNLDDEIISTQNTMFLSLLI
PYLQSAIFLFIIRCLE-MKYGRETMRKDPVF-RISPRSRENRPNPEEPEE----EDEDVQ
TERVKTANALT-SANSE--EKPVIMASCLHKEYKGKKKSCFLTRK--KKIAIRNVSFCVN
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGHNGAGKSTSIKMITGDTKPTAGVVV-SQ--GCTA-SLGKQKDD----IPTF
LGYCPQENSLWPSLTVKDHLELYAAVKGLGKDDAA-----LSISR----LVGALQLQDQQ
KRPVKALSEGIK---RKLCFALSILGNPPVVLLDEPSTG----MDPEE-QQRMWQAIQTI
VKNTGRGALLTTHHMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEVKIKEPTQTELL
HTEILKLFPQAA--RQERYSSM--MAYKLPVEDVHPLSQAFFKLEAVKQTFDLE---EYS
L-SQATLEQV----------------------------------------------FLEL
SKEQEMGNFD-DEVDT-TVKWKLLPQEEP----------------------
ENSDNOP00000000497 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSERERSVCQQTRALLCKNILKKWR-----MKR
EPLMEWLNS-LLLLLSLY--LFS---NIHEVNDFSSLPPL--DLGRVDS--FSRT-DFTI
VYTPVTN------TTQAIMNKVASVHFM----------------------------T--A
NK--VLGLSDEKSIEELTKNY-----PGEIVRVIFSNTF-SY----HLKFLLGYRIPTK-
---KE----HTDHTG----------------NCKRH---R-KVMFC-------SYNQMGK
WSMPSINTQVLFINIFLQITTNHSVMEKLMSITGESMKINSF---------ISQEGIM--
TDFFIFFCIISFSPFIYYVSVNV-----------TRERKKIKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALLLAF----------SIKYIQFIILTGFLVVFTLFLLYG
LSLVSCSIILSV----------------------------CMRKSVEQTLTLYIK-----
FL-ILVFWGS--------LGFTALYRYLPLPLEWILSFLSPFAFTLGLTQLLRVDYD---
------LNSNASPAPLDHSYIILATYFMLALDIILYLILTIYFEKILPNE---YGCRRSP
LFFLKSSFWSQQQKA-DHVS--FEDEIDSNSS-PNDSFEPVSSEFHGKEVIRIRNVTKEY
-------------KGK------P-----------------------------DK
PF03193 // ENSGT00760000118965_1_Domain_2 (1675, 1718)
IEAL--
--K--DLVFDLYEGQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNKLSEVDDLENISK-LTGVCPQS--NVQFEFLTVRE-NLRLFAKIKGILPKEVD-KEVQRVLLELGMNNISDTLAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRYQVWNLLKKR------------------KTDRAILFSTQFMDEAD------------------------------------------------L---------------------------LAERKIFLSKGKLKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------MCIQEKI-TSLVKQH--------------------IPDAKL----SAESEGKLIYT--LPLER--TNKFPELYKDLDSHPDL---------GIENY--GVSMT----TLNEVFLKLEGK-SAIEES---------DVGIL-GDV-QEERA--------GDTESLVEVE----QILSSFN------EMRET-T-----------------------SGMALWGQQICAIARV---------RFLKLKHE-KKAILSLLLILGVGFFPLLLEYILLKIHES-SYTWNLSPHMYFLAPGQQP--HDPLTPLLII-----NK--TET-RIDDFIHSVERQDIALEVDAFG----TRNG-TDDPSYN-GAITVSGNE-KNYN---FSLACNTKRLNCFP-VL-MDIVSNGLLGMFK--------------------PSAH--IQTDRSTFSTEEQ-----SNPF---EFL-----GGILFWLMLASGCSPYIAMSSIDDYKNKV-RSQLRISG-LFPSAYWFGQ-ALVDVPIY----------------GSIFVFIYL---MDYLLGPQEA-----TFKVANQI-MQIPCAVGYTISLIFLTYIISFIFRKGRKNSGIWSFCFYII-----TFFSVAGL-VF--SAYGR-DPLFYLIFLIPHS-----TLI--------GSLFLSLRIL----------VF------SAFVEE-EWDVTPYLMFLIPFLHFIVFLFILRCLE-WKFGKKLMRKDPVF-RISPRSYDVSKNPEEPGE----EDEDVKMERERTANALS-STNSD--EKPVITATCLRKEYAGKRTHCFSKRK--RKLAIRNLSFCVRKGEVLGLLGHNGAGKSTFIKVITGDTKPTAGQGL-LK--GSSG-------GE----AVGFLGYCPQENALWPSLTAREHLEVFAAVKGLRGAAAQ-----AAIAR----LVEALQLQDQLKVPAKALSEGLK---RKLCFALSVLGSPAVVLLDEPSTG----MDPEG-QQQMWQAIRATIRDTERGALLTTHYMAEAEAVCDRVAIMVSGRL------------------------------------------------------RCIGSIQHLKSK-FGKDYLLEIKVKTPEQGELLHAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLENVKRSFDLE---EYSL-SQSTLEQV----------------------------------------------FLELSKEQELDDFE-EELDP-SVKWKLLPQEES------------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSVPTK--GSVTIYNNKLSEVDDL
ENISK-LTGVCPQS--NVQFEFLTVRE-NLRLFAKIKGILPKEVD-KEVQRVLLELGMNN
ISDTLAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRYQVWNLLKKR---
---------------KTDRAILFSTQFMDEAD----------------------------
--------------------L---------------------------LAERKIFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CIQEKI-TSLVKQH--------------------IPDAKL----SAESEGKLIYT--LPL
ER--TNKFPELYKDLDSHPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIEES---------DVGIL-GDV-QEERA--------GDTESLVEVE----QILSSFN--
----EMRET-T-----------------------SGMALWGQQICAIARV---------R
FLKLKHE-KKAILSLLLILGVGFFPLLLEYILLKIHES-SYTWNLSPHMYFLAPGQQP--
HDPLTPLLII-----NK--TET-RIDDFIHSVERQDIALEVDAFG----TRNG-TDDPSY
N-GAITVSGNE-KNYN---FSLACNTKRLNCFP-VL-MDIVSNGLLGMFK----------
----------PSAH--IQTDRSTFSTEEQ-----SNPF---EFL-----GGILFWLMLAS
GCSPYIAMSSIDDYKNKV-RSQLRISG-LFPSAYWFGQ-ALVDVPIY-------------
---GSIFVFIYL---MDYLLGPQEA-----TFKVANQI-MQIPCAVGYTISLIFLTYIIS
FIFRKGRKNSGIWSFCFYII-----TFFSVAGL-VF--SAYGR-DPLFYLIFLIPHS---
--TLI--------GSLFLSLRIL----------VF------SAFVEE-EWDVTPYLMFLI
PFLHFIVFLFILRCLE-WKFGKKLMRKDPVF-RISPRSYDVSKNPEEPGE----EDEDVK
MERERTANALS-STNSD--EKPVITATCLRKEYAGKRTHCFSKRK--RKLAIRNLSFCVR
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STFIKVITGDTKPTAGQGL-LK--GSSG-------GE----AVGF
LGYCPQENALWPSLTAREHLEVFAAVKGLRGAAAQ-----AAIAR----LVEALQLQDQL
KVPAKALSEGLK---RKLCFALSVLGSPAVVLLDEPSTG----MDPEG-QQQMWQAIRAT
IRDTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEIKVKTPEQGELL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLENVKRSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFE-EELDP-SVKWKLLPQEES----------------------
ENSECAP00000000222 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MDKMALASFM------------------------------KG
RT--VIGTPDEETIDIVLAKK-----HPEMVGVVFNDSF-SY----RLKFPWGYGIPII-
---KE----HLEYSE----------------HCWAD---QDEP-FC-------SLTTF--
WQRGFVAFQTAINAAIIEVTTNHSVMEELTSVIAINMRTLPF---------IFNRGSI--
SEWFIFICVVYFSPFVYFASLNV-----------TRERKKFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFIMSIFMAL----------VITSIQIIVMTGFMVIFTLFILYG
LSLITLAFLLSV----------------------------LIKKPILT---GLAG-----
FL-FTVFWGC--------LGFTALFRQLPSSLEWVLGLFSPFAFTAGMAQILHLDYH---
------MVGAIFPDPSGEAYTMIVTFFILALDTLLCLILTLYFERVLPDE---DGRWHSP
LFFLKTSYWSQHQ-NTYHEV--FENEINAEYF-SDDSFEPVSPEFHGKEAIRIRNVEKKF
-------------NGK------P-----------------------------EKIEAL--
--Q--GIFLDIYEGQITAILGHGGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSVSTE--GSATIYNTQLSEITNM
EEIRK-NTGFCPQF--NIQFEFLTVRE-NLALFAKIKGIQPKEVE-QEVKRVMMELDIQN
IQDVIAEKLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHQVWNLLKER---
---------------KTGRVILFSTQYMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYLL--SLHRN-E----------------------T
CNPERI-TSLIRQH--------------------VPDAKL----TAESEEKLVYS--LPL
ER--TNKFPDLYSDLDKCSDQ---------GIMNY--GVSMT----NLNEVFLNLEGK-S
ASDEP---------DFGTQ-KQE-KIKVT--------RDTGIESETQ----QALCSLP--
----EMRKA-I-----------------------STGTLWRRQVLAMARL---------R
FLKLRHE-RKVLLSLLLVLGIAFIPTICEKIMSMAFFY-PHRWELSSSMYFLSLEQLP--
QTPLTSLLII-----NN--TGS-NIEDLVRSLKRQDIVLEIGDFR----NRNG-SDDPSY
N-GAIIVSGDS-KDYR---FSVACNTKRMNCFP-VL-MGIVSNALLGMFN----------
----------FTEL--IKMERSTFPVDDA-------------MLGIGFLDWSL-LLLLAN
CVSPYIGMSSINDYKQKA-QSQLWISG-LFPSAYWCGQ-ALADIPLY-------------
---GLILLSIRL---THHFMFS----IS---ILSWGLVFALVVCMIGCAASLIFLTYVIS
FIFRKGRKNSSFWCLGFLII-----SIFVFIIL-VS--THFER-FKLILCMILIPLY---
--TLS--------GFFTFLIELS----------FINMRSSESLDIGIDDVNETILLTILI
PYLQSVIFLFVIRCLE-MKYGKEPMRKDPVF-RICPRSRESHPNPEEPEE----EDEDVQ
IERVRTAKACT-TPNLD--EKPVIMASCLHKEYKEKKKSCFSRRK--KKIAIRNVSFCVN
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIKMITGDTEPTAGVVV-LQ--GCRA-SPSPQGDD----LVKF
LGYCPQENPLWPSLTVKEHLELYAAVKGLDKEDAA-----LSILR----LVDALKLQDQL
NLLVKALSEGIK---RKLCFALSILGNPSVVVLDEPSTG----MDPEG-QQQMWQAIRTI
VKNTERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEVKMKELTQVEPL
HAEILKLFPQAA--RQERYSSM--MAYKLPVENVHPLSQAFFKLEAVKQTFDLE---DYS
L-SQATLEQV----------------------------------------------FLEL
SKELELGNLD-DEVDA-TVRWKLLPQEEP----------------------
ENSPANP00000016556 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLK-V
VYTPISN------LTQQIMNKTALAPLL------------------------------KG
TS--VIGAPNKTYMNEILLEN-----FPYAMGIIFNETF-SY----KLTFLQGYNIPLS-
---KE-----EGFSA----------------HCWDG---YD-EFPC-------KLTKY--
WNRGFVALQTAINTAIIEITTNHSVMEELMSVTAITMKTLPF---------RSKDLLH--
NEIFIFFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFITI----------IITFTEIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILSICSPFAFTAGMTQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSILLLDGFIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERRYSP
LFFLNSSSCFQHQ-GTDNKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-IIGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHPQEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2301)
TTGLDPFSRDQVWSLLRQH---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SIFLK---RRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTKNKEKLVYT--LPL
ER--TNIFPDLFSNLDKCSDQ---------GVTGY--DISMS----TLNEIFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMHLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFG
PF12698 // ENSGT00760000118965_1_Domain_4 (2301, 2704)
IAIFPLIVENIIYAMLSE-KIDWEFKTELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMLN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTVLPDGSFFLFLVLC
SISPYITMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---ILILLAMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFLIYMIS
FIFRKRRKNSALWSFYFFFA-----SIIMFVTT-LI--SNFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GFKTFLETRD----------QQHYRDSPE---ANFKLSATDFLVCFI
PYFQTLLFVFVLRCME-LKYGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERVRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGKVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTAREHLEVYAAVKGLRKVDAR-----LTIAR----LVSAFKLHEQL
NVPVQKLTTGTM---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKEPSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQAFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEVDT-TMRWKLLPHSDEP---------------------
ENSPANP00000016557 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEVVGVIFRDTF-SY----QLKFNWGYRIPPI-
---KE----YTEYTA----------------HCWAM---HGEI-FC-------YLAKY--
WLNGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFIFTCLVSFSSFIYFASLNV-----------ARERGEFKKLMSVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFIAGMAQITHLDNY---
------LSGVIFPDPSGDSYIIIATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHDGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITAM
EEIRR-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2514)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAKL----TTESEEKLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GLRNY--GVSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATL---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVIRE-THCWEFSPSMYFLSLEQIP--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNIKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSHDDI-------------VLDLGFIDGSI
PF12698 // ENSGT00760000118965_1_Domain_4 (2514, 2770)
FLLLITN
CISPFIGMSSISDYKKKV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWELVFVLVVCIIGCAASLIFLTYVLS
FIFRKWRKKNGFWPFGFFII-----LICVSTIL-VS--TQYET-PNLILCMIFIPSF---
--TLL--------GYIMLLIQFS----------LMYMRNLDSLDSRINEVNKTILLTTLI
PYLQSLIFL
ENSGT00760000118965_1_Linker_4_5 (2770, 2873)
FVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLT--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMITGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVKAL
HTEILKLFPQAA--RQERYSSF--MAYKLPVEDVHPLSRAFFKLEAVKQTFNLE---EYS
L-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEEP----------------------
ENSXETP00000047607 (view gene)
------------------------------------------------------------
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------------------------------------------------------------
---------------------------RKLRETSLFQQTMALFWKNLLLKWR-----RKW
HTILEWLQN-LAFVLVML--LISVMGLSTFVQLEYNSPAE--VLGRLDAVD-RSN-NFKV
GYVYTSP------TSRDIMEKVAKSIII------------------------------PG
IK--VQEYSDEGNLLDD-MTN------KAVVGVTFVDKF-SY----HIRYPINNIAY-P-
---KM----SENKPE----------------ACFCA---PG-SQAC-------YPTYY--
WSRQFLSLQASIDSAIIELTSNHSVWDNMASVVTVRMKSTVA---------SFRQYFH--
IGTFIFLMPMCYVSLMYLL----------SLYI-TRERREMRELLKMMRLKDLA------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-LFYILILANLMTL-----------VTKAFVFVQSSYGIIMFLFVFYG
IALMSFTFMLSA----------------------------LFRSPRAT---AIAG-----
FF-ITLFLSA--------LGLVLLRKDFPQALAVLLSIFPQFAFAVGLTESVHMESD---
------LQGVYFSDMAGDSSHVLSSFISLALDSIFYMGLTLYFEKVLADK---HGLKYEP
FFFMKSSYWSKKKLS-PVL---TQTEDSGESS-MGEFFERVPIDLYGKEAIRINKVMKKY
-------------CDQ------D-----------------------------KNIEAL--
--R--GLDLNIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLLNILSGLCPASD--GSATVYSYKLSDMQHL
EEIKK-RTGFCPQS--DVKFNPLTVKE-NLTVFAKIKGIPRKQIK-HEVQKVLSDLQMND
IENVEADNLSGGQRR-KLTLGIALLGDPQV--LLLDEPTAGLDPCSRHHIWTILKEN---
---------------KADRVTLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAVISNGR
LKCVGS--SLFLK---RKWGI---GYHL--RMQVS-P----------------------T
CDVELM-TSIIKQH--------------------VPDAKL----TAQNEEELTYT--LPF
EN--MDAFPDLFLHLDGQVGN---------SIVNY--GVSMT----TLDDVFLKLEGE-G
EIEKYFIR---------MF-VEI-SKNGP--------AKKVNLME-I----TQLFSYI--
----YSGSATL-----------------------SGLSLWRQQVLAIARV---------R
LLKLKHD-SKTFRSILILLALFIIPIIMTTIVIKIFHK-VITWELTPSLYFQHPEDRF-H
-RYYTDLQIY-----NNTETGS-SIEDFLGALKEQNIAVQVVNGE----Y---DMETTFY
R-GAIEVSQAT-KGYG---FTIVGNPKAQNALP-VL-VNIISNALLMIFN----------
----------STEH--IRVWNHPVTEKS----------MEHVCYTFSSRRF--MLLLFAS
GLAPHFAMSSIEDRRI-KARTQLRISG-IFPSAYWFGQ-ALVDVPLY-------------
---WILLFLMVA---ILFSFNS--Q----VIFSFVPAIILITGV-IGYGAAVVLYVYVIS
FVFGRGKSHHDGWSIFFVIM-----VKCK-IICN------RLV-YPLDDKSAFIPMILLD
VVSTY------------------AGQMYGCLTTQKSQ-KEYNKSCINQSW--HVYIQYIN
PFLHIVIFSVILWVLE-RVFGMRSLKTNLFY-RLSTRGYTVYNTNEHIGTLEPNTDEEVL
AERERVKMSST-TNNME--EKPIIIVDSLRKEYKVKKGKSFFKKN--KKAATKNISFCVR
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGPNGAGKTTSIYMLAGEIRPTAGEVL-LC--GTDPDKSQNSQYD----PTGS
LGYCPQDNPLWPNLTVKQHLEIYAAVKGLKKKDAE-----TAIKR----VSEALELKEHL
EKAARKLSAGVS---RKVCFAISMLGNPNIVLLDEPSTG----LDPKG-QQRLWRAIRSA
FRNKDRGAILTTHYMEEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQQLKSK-FGKGYLLEIKVKNSNQVDQI
HNEIIQIFPHAA--RQDRFSSL--LVYKIPVENVQSLSKAFLDLEEAKRAYNIE---EYS
F-SQPTLTQV----------------------------------------------FIEL
TKEQEREDFD-S--AS-TFQWKQLRTESEGLA-------------------
ENSMLEP00000018652 (view gene)
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MKYEIEIMNKDPVF-RVSPRRRETHPYPEEPEE------EDVQ
AERVQAANALT-TPNLE--EEPVITASCLHKEYYEAKKSCFSTRK--KKIAIR
PF00005 // ENSGT00760000118965_1_Domain_5 (2874, 3064)
NVSF---
-------LGHSGSGKSTSIKMTTGFTKPTAEAVV-LQ--GNRA-SVKQQHDN----SLKF
LGYCPQKNSLWPKLTMKEHLELYAAVKGLGKEYA--------------------------
---------------RKLCFVLSILGNPSVVLLDELFTR----MYPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAKAVC--------GTL---------------------------
---------------------------GCIGSIQHLKNK-N-------KKMKKPTQVEAL
HTEILKLFPQAA--QQERRSSL--MAYKLPVEDVHPLSQAFFKVEAVKQTFNVE---EYS
L-SQGTLEQV----------------------------------------------FLEL
RTEQALGNVD-DRSTA-V---------------------------------
ENSCAFP00000016107 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHISVGQQTWALLCKNFLKKWR-----MKR
ET
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWFFS-FLLVLFTY-QLSS---NLHQVNDFTQLPAM--DLGRVDN--FNDS-NYVI
AFAPESK------TTQEIMNKVASAPFM------------------------------KG
RT--VLGWPDEKSMEDLDLNY-----SVDAVKVLFNDTF-SY----HLKFFWGGRIPKV-
---KE----HRDHSA----------------HCQVM---D-EKVTC-------EASMF--
WEKGFVAFQAAINAAIIEITTNHSVMEELMSITGINMKILPF---------VAQAGVV--
TDLFIFFCIISFSAFIYYVSVNV-----------TQERQYIKSLMMMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFIFIVATLMAL----------IVKSAQIVVLTGFVVVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRHLPAFLEWTLCFLSPFAFTVGMAQLIHLDYD---
------VNSNIHLDSSDNPYLIIATLFMLVFDALLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRRSP
WFFLKSSFWFQHPRA-DHVA--LENEIDSDSS-PNDSFEPVSPEFHGKEAIRIRNLKKEY
------------GKGN------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVFDIYEGQITALLGHSGAGKTTLLNMLSGLSTPTS--GSVTIYNHTLSEMTDL
ETVSK-LTGVCPQS--NVQFDFLTVKE-NLRLFAKIKGIQSHEVE-QEIQQVLRDLEMEN
IQDILAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2447)
AGSDPLSRHRVWNFLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDSI-TSLVKQH--------------------IPDAKL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDES---------DTGIW-GEL-QNNRT--------KDTGSLVELE----QVLSSFK--
----ETKKS-I-----------------------SGMALWRQQLCAIAKV---------R
FLKLKNE-KKTLLTILLLFGISLCPQLLEHLFYELYQK-SYSWGLTPTMYFLSPGQPP--
QAPLTHLLVI-----NK--TGS-SIDNFIHSLRQQNIALEVDAFG----IRNG-PNEPSY
N-GAITVSGDD-KDHR---FSIACNTKRLNCFP-VL-MDIISNGLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2447, 2743)
GIFN----------
----------SSEH--IQTDRSTYFEEHMF-------Y-EHGYL-----SNAFFWIPVAA
CFTPYIAMSSIGDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYVFSPDEI-----IFIIQNLL-VQILCSIGYVSSLIFLTYVIS
FIFRNGRKNSGIWSFFFLII-----TIFSIVATDL---NEYGF-LGLFLCTILIPPF---
--TLI--------GSLLIFSEIS----------PDS------
ENSGT00760000118965_1_Linker_4_5 (2743, 2873)
MDYLGASEQQIVFLALLI
PYLHFFIFVFVLRCLE-VNFRKKSMRKDPVF-RISPRSSSIFPNPEEPAG----EGEDVE
GERRRTTNAET-LADFD--EKPVIIASCLRKEYAGKKRNCFAKRK--KKVAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTNPTAGQVI-LK--GNSE-------GD----SLRF
LGYCPQENVLWPNLSVREHLEVFAAIKGLKKGDAT-----VTITR----LADALKLQDQM
KLPVKTLSEGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQTIRAT
FGNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSR-FGKDYLLEMKVKTPTQVEPL
HCEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVKWKLLPQEDP----------------------
ENSPPYP00000024051 (view gene)
------------------------------------------------------------
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---------------------------------------------------------M--
--P--DVVFDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLSVPTS--GSVTIYNHTLSRMADM
ENISK-FTGFCPQS--NVQFGFLTVKE-NLRLFAKVKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPTAGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-K----------------------R
CDPESI-TSLVQQH--------------------ISDAKL----TAQREEKLVYI--LPL
EK--TNKFPELYRDLDRCSNQ---------GIEDY--GVSIT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDTGSLVELE----QVLSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKKE-RKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-TIDNFLRSLRRQNIAIEVDAFG----TRNG-TDDLSY
N-GAIIVSGDE-KDHR---FSIACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSEH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPMAA
SFTPYIAMSSIGDYKKKA-HSQLRISG-LYPSAYWFGQ-GLVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIV-----VIFSIVATDL---NEYGF-LGLFFGTILIPPF---
--TLI--------GSLFIFSEIS----------PDS------MDYLGASESEIVYLALLI
PYLHFLIFLFILRCLE-MNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EEEDIQ
MERMRTVNAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIATRNVSFCVK
KGEVIGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTIKMITGDTKPTAGQVI-LE--GSGG-------GE----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDSM-----IAITR----LVDALKLQDQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQGFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDLE-EDFDP-SVKWKLLLQEEP----------------------
ENSRNOP00000005489 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVRQQTCALLQKNLLKKWR-----LRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLMEWMSS-LLLLLFLC--WYP---HGHEATDFSSVPTK--DLGRVDS--FTQS-GFMI
GYTPVTS------TTRQIMEKVAAVPFM----------------------------A--G
RK--VLGLLDEENIRELTESH------QEVIRVIFSDTF-SY----HLKFQFGQRIPKS-
---RE----HGDHEA----------------HCFEM---Y-EDVDC-------LISIF--
WKKGFVALQAAINAAIIETTTNHSVMEKLLSVSGKFMKIHPF---------VRQEGIL--
TDFFIFTCIVSFSPITYFVSISV-----------ARERKKMKGLMMMMGLRDSA------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFVMALSLAL----------VIKSVQFLILTSFTVVFSLFLLYG
LSMISLAFLMSV----------------------------LVRKSVLT---GLTV-----
FL-LTIFWGS--------LGFTALYRYLPAPLEWTLSLFSPFAFTLGMAQLLRVDYD---
------LNSNAPPDPAGSSNLIAATNFMLAFDALLYLALTM
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKVLPNE---YGHQRSP
LFFLKPSFWVQPRKP-AHVI--LEDGIDPAPL-SGGSFEPVSPEFHGKESIRIRNISKEY
-------------KGK------P-----------------------------SKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDIYEGQITALLGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNRLSEMADL
ESVFR-ISGVCPQS--NVQFDFLTVRE-NLRLFAKIRGVPPQEVE-KEVQRVLLELEMKN
IQDILARNLSGGQKR-KLTFGTAILGDSQI--FLLDEPTAGLDPFSRHRVWNLLKER---
---------------KADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISRGK
LKCAGS--SLFLK---KKWGV---GYHL--SLQLK-E----------------------V
CVPENI-TSLVKQH--------------------IPEAKL----SAERERTLVYT--LPL
ET--TYRFPELCQSLDSCPGL---------GIDSY--GVSMT----TLNEVFLKLEGK-S
AIEEP---------EVDIV-GEG-QTERS--------GDTERLMEME----QTLSTLT--
----ETKKK-T-----------------------GSLALWRQQTCAIAKA---------R
LLKLKHE-RKTLLSVLLVLGVALCPLLFESIKMKILQS-AYTWDLSPHSYFLAPGQQP--
HGMLTQLLII-----NK--TEA-SIDDFIQSVERQNIALEVDASG----ARDG-TDDPSF
N-GALTVSGGE-KTHS---STDLGNTAFLKIFL-ILFLNSFVSGVFPKCM----------
----------SGAA--VATMNTTFCWDEI-----TNPL---QQL-----GKTTFWLTLTS
ACPPYIAMSSVTDYKNKV-WFQLRVSG-LFPSAYWFGQ-ALVDIPLY-------------
---CFVFLFMSL---MDYLLGFPDA-----TLIVITHV-LQIPCSVGYAISLIFLTYVIS
FISRKGKKNSGIWSLCFYII-----TMFSVVAM-LL--DFNVD-AILYCIIFLLPPS---
--TLI--------GCLILSMHLF----------IY------RISREE--SIVEPFLVFLI
PLLHVFIFIFTLRCLE-WKFGKKTMRKDPIF-RISPRNNDVHQNPEEPEG----EDEDVQ
MERMRTASALA-STSFD--EKPVIVASCLRKEYAGKWKHCLSKKK--AKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEILGLLGHNGAGKSTSLKMISGDTKSTAGQVL-LK--GSRE-------GD----ALGF
LGYCPQENALWPNLTVKEHLEVFATVLGLSKSHAA-----VTITR----LADALQLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSILLLDEPSTG----LDPEG-QQQIWQAIRAI
IKNTDRGALLTTHYMAEAEALCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLEQVELL
NTEVLRLFPQAA--RQERYSPL--MVYKLPVEDVQPLSQAFFKLEKVKQTFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQEMDGFE-EELDS-SIKWKLLPQEEV----------------------
ENSLAFP00000000069 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MYKKKKSVYQQTQALLCKNFLKKWR-----MKR
QSLLEWGLP-IILGLYMG--LFS---YFKESNHIPETPSQ--DLGRADK--FNSSYIM-I
VYTPVSN------VTQQIMNKTASALFL------------------------------KG
KG--VIGTPDKKSMDKIILEN-----FPYAVGIIFNDTF-SY----KLMFFQGYAIPYK-
---KE-----DDFSA----------------RCWNG---YY-GTFC-------SQSLY--
WERGFVTLQTAIDAAIIEITTNHSVMEELMSVTGINMKILPF---------LSKYIFQ--
NDMFIFYCLIYFSPFIYFASLDV-----------TKERKKLKDLMKIMGLQDSA------
------------------------------------------------------------
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------------------------------------------------------------
---FWLSWGLIY-AGFIFFISILITI----------VITSTQIIVRIGFMVIFTLFFLYG
LSLIGLVFLMSV----------------------------LLKKTSLT---SLAV-----
FL-LKLFWGC--------VGFTVLHKQLPSSLEWIMSIWSPFAFTAGLARITHLDYK---
------LNDASFTDLSGDSYIMIGTFSMLAFDGLFYLVLALYFDRILPFG---NELCYSP
LFFLNSSPCLQHQ-RTDYEV--VEKEMDSENS-ADDCFEPIAPEFQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
--K-AGLFFDVYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSRAGKSSLLNILNGLSIPTE--GLVTIYNRKLSEKQDL
EEIRK-ITGVCPQF--NIQVGVLTVKE-NLRLFAKIKGIQPQEVE-QEVQRILLELDMQS
IQDNLAKNISEGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHRVWNLLKER---
---------------KTNHVILLSTNFTDEAD----------------------------
--------------------I---------------------------LADRKAIMANGR
LKCAGS--SLFLK---RKWGL---GYHL--SLFRN-E----------------------A
CDPEKV-TFFINHH--------------------IPDATL----KTESKEKLVYT--LPL
ER--TSVFPDLFSDLDKCSGE---------GVMTY--DIYMS----TLSEVLAKLEGK-S
TIKQD----------------FE-QAEVK--------RDPGSLDDLE----AACSSLP--
----ETPKA-V-----------------------SDMALWRQQVCAIARL---------R
FLKLKHG-KKELLTLLFVFGIAALPLIVEMILYAILNQ-NGDLEFKPDLYFLSPGQLP--
QEPHTSLLVI-----NN--TES-NIEDFIHALKDQNIVLEVDDFE----NRNG-TDDHSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-VL-LNIVSNGLLGMFN----------
----------LTKY--IRIERDMLFSHYI-------------PIWTELPEGSLFLVLVVC
SISPYIAMSSISDYKSKA-QSQLWISG-LYPSAYWCGQ-ALVDINLY-------------
---IFILLAMYL---VFYLTYL---VNF---HLTSRIVFGVVVTTLGYAASLVFLTYVIS
FIFHKRRKNTILWSLCFYVI-----TVLTFDGI-IL--YQFSY-TILIVIMFLVPSL---
--TIS--------GFFMFATARI----------NEQYRISEG---EDHDLSEVDLLVSLI
PYFQVMIFLLVLRCLE-MKCGKKTMQKDPVF-RISPQSRDARPNPEEPVD----EDEDVQ
AERIRTATALT-TSNID--EKPVIIASCLHKEYAGKKKCCFSKRK--KKIATRNISFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEILGLLGPSGAGKSSSIRMISGISKPTAGEVE-LK--GSNSV-WGHQEDN----VVKF
LGYCPQENPLWPNLTVREHLEVYAAVKGLRKADAA-----ATITR----LVDAFKLQELL
KVPVQKLTPGTS---RMLCFVLSIMGNPPVLLLDEPSTG----LDPTL-QQQMWQAIQAA
IKNSEKGAVLVTHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGHIEHLKSK-FGKDYILELKLKEPSEVTVV
HAEILKLFPQAA--RQERYSSF--VAYKLPAADVHPLSQAFHRLEAVKRNFNLK---EYS
L-SQCTLEQV----------------------------------------------FLEL
SKEQELGDFD-EEVDT-TMTWKLLSHSDDP---------------------
ENSGGOP00000015014 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNMKQKSVYQQTKALLCKNFLKKWR-----MKR
ESLL
PF12698 // ENSGT00760000118965_1_Domain_0 (545, 1542)
EWGLS-ILLGLCIA--LFS---SSMRNVQFPGMAPQ--NLGRVDK--FNSSSLM-V
VYTPISN------LTQQIMNKTAHAPLL------------------------------KG
TS--VIGAPNKTHMDEILLEN-----LPYAMGIIFNETF-SY----KLIFFQGYNSPLW-
---KE------DFSA----------------HCWDG---YG-EFSC-------TLTKY--
WNRGFVALQTAINTAIIEITTNHPVMEELMSVTAITMKTLPF---------ITKNLLH--
NEMFILFFLLHFSPLVYFISLNV-----------TKERKKSKNLMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIISIFVTI----------IITFTQIIVMTGFMVIFILFFLYG
LSLVALVFLMSV----------------------------LLKKAVLT---NLVV-----
FL-LTLFWGC--------LGFTVFYEQLPSSLEWILNICSPFAFTTGMIQIIKLDYN---
------LNGVIFPDPSGDSYTMIATFSMLLLDGLIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPYG---DERHYSP
LFFLNSSSCFQHQ-RTNAKV--IEKEIDAEHP-SDDYFEPVAPEFQGKEAIRIRNVKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLSLFAKIKGIHLKEVE-QEVQRILLELDMQN
IQDNLAKHLSEGQKR-KLTFGITILGDPQI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2304)
TTGLDPFSRDQVWSLLRER---
---------------RADHVILFSTQSMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---KRWGL---GYHL--SLHRN-E----------------------I
CNPEQI-TSFITHH--------------------IPDAKL----KTENKEKLVYT--LPL
ER--TNTFTDLFSDLDKCSDQ---------GVTGY--DISMS----TLNEVFMKLEGQ-S
TIEQD----------------FE-QVEMI--------RDSESLNEME----LAHSSFS--
----EMQTA-V-----------------------SDMGLWRMQVFAMARL---------R
FLKLKRQ-TKVLLTLLLVFGIAI
PF12698 // ENSGT00760000118965_1_Domain_4 (2304, 2704)
FPLIVENIMYAMLNE-KIDWEFKNELYFLSPGQLP--
QEPRTSLLII-----NN--TES-NIEDFIKSLKHQNILLEVDDFE----NRNG-TDGLSY
N-GAIIVSGKQ-KDYR---FSVVCNTKRLHCFP-IL-MNIISNGLLRMFN----------
----------HTQH--IRIESSPFPLSHI-------------GLWTGLPDGSFFLFLVLC
SISPYMTMGSISDYKKNA-KSQLWISG-LYTSAYWCGQ-ALVDVSFF-------------
---VLILLLMYL---IFYIENM---QYL---LITSQIVFALVIVTPGYAASLVFFMYMIS
FIFRKRRKNSGLWSFYFFFA-----STIMFSIT-LI--NHFDL-SILITTMVLVPSY---
--T
ENSGT00760000118965_1_Linker_4_5 (2704, 2873)
LL--------GLKTFLEVRD----------QEHYREFPE---ANFELTASDFLVCFI
PYFQTLLFVFVLRCME-LKCGKKRMRKDPVF-RISPQSRDAKPNPEEPID----EDEDVQ
AERIRTATALT-TSILD--EKPVIIASCLHKEYAGQKKSCFSKRK--KKIAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVQ
EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVE-LK--GCSSV-LG------------H
LGYCPQENVLWPMLTLREHLEVYAAVKGLRKADAR-----LAIAR----LVSAFKLHEQL
NVPVQKLTAGTT---RKLCFVLSLLGNSPVLLLDEPSTG----IDPTG-QQQMWQAIQAV
VKNTERGVLLTTHNLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVKETSQVTLV
HTEILKLFPQAA--GQERYSSL--LTYKLPVADVYPLSQTFHKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQEVGNFD-EEIDT-TMRWKLLPHSDEP---------------------
ENSMPUP00000014329 (view gene)
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---------------------------MMKREISVCQQTWALLCKNLLKKWR-----LKR
ESFMEWLTP-LLLLLCLS--VYP---TSHEFNDFSSLPAM--DLGRVDS--FKDS-TFSV
IYTPVTN------TTQQIMNKVALASFM----------------------------K--D
AK--VLGLSKEKNIKELMSDN-----PDEVIQVIFTNTF-SY----HLKFLLGYRIPTK-
---KE----HRDHEA----------------HIYEK---TYIRTFI-------AVAFF--
SLSGCQAYSRNIINVFSQTATNHSVMEELMSVTGKNMKIHPF---------VSQGGIE--
ADFFIFFCIISFSSFTYYASLNV-----------TRERKKMKGLMRMMGLQDSA------
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---FWLSWGLLY-GVFIFIMALSLAL----------IIKSVQFVILTGFTAIFTLFFLYG
LSLIALAFLMSV----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRQLPTSLEWILSFLSPFAFTLGMAQLLRLDYD---
------LNSNAFPNPSDYSNLIIATNFMLAFDLLFYMALTIYFEKILPNE---YGHGYPP
FFFLKSSFWSRQQKA-DHVV--LEDEIDSDPS-SNDSFEPVSPEFHGKEAIRIKPNTQKF
----------QVQKLK------P-----------------------------GICTLI--
--K--DLVFDIYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1784)
STLLNILSGLSVPTK--GSVTIYNNKLSEISDL
ENIIK-LTGICPQS--NVQFDFLTVKE-NLRLFAKIKGIQSHEVD-KEVLNTFIKLYLCK
SCLN-----VGPKSN-DMNWAQRVTPNP----FHV----------SPQILYHLITLGHD-
---------------LPGKNGQLPNKLSSLLF----------------------------
--------------------S---------------------------ISDRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHLNTSLQLN-E----------------------T
HVQENI-TSLIKQH--------------------IPDAKL----SAESEGKLVYT--LPL
ER--TNRFPAKYSSVHICPSM---------EIQKK--KEKVN----LLSQAFLRAIGKIS
NLEEA---------YMATL-GEA-QAERT--------GDTERLVEME----QVLSSLN--
----ETTKT-I-----------------------GGLALWKQQICMIARV---------H
FLNLKHE-RKALLSLLLILGVGICPLLLRTIHNRIYEM-SYTWELSPHLYFLAPGQSP--
HDPLTQLLII-----NT--TGA-SIDDFIHSVEHQNIALEVDVSG----TKTG-VDDLSY
N-GAIIVSGNT-ENYS---FSLACNTKRLNCFP-VL-MDIISNALLGMII----------
----------PSAH--IQTDRSTFIVDRE----SSSPY---EFQ-----VYTIFWLILIS
SCSPYIAMSSIDDYKSKV-QSQLWISG-LFPSAYWCGQ-ALVDVPMY-------------
---SLSFLLMYL---IDYGLNFDGT-----LMTLISEI-IQILCSFGYAASLIFLTYVIS
FIFRKGKRNSGIWSFCFFMI-----CSISVFIL-FF--ESFGH-VTLYCITFLVPQA---
--TLI--------GCMLLYYEVA----------IF------YFLTEEELASVEAFLIVLI
PFLHFIIFLFILRCLQ-WKFGKKSMKKDPFF-RISPRNPDVCQNPEAPEG----EDEDVQ
MERMRTADALN-STNFE--EKPVIIASCLRKEYAEKRKCCLSKRK--KKIATRNVSFCVR
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIRMITADTKPSAGQVL-LK--GSNG-------EA----SPGF
LGYCPQENVLWPSLTVKEHLEVFAAIKGLRKVDAA-----VTIAR----LADALKLQDQL
KQPVKALSVGIK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QLQMWQAIRAT
VKDTERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKNYLLEMKVKTLAQRESL
HQEILRVFPRAA--RQERYSSV--MVYKLPVEDVRPLAQAFFMLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFD-EELDP-SVKWKLLPQEDP----------------------
ENSVPAP00000000101 (view gene)
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---------------------------TSKRHLSVAQQTRALLRKNFLKKWR-----MKR
EALLEWFFS-LLLELFAY-LFSS---NLHQVNDFHQPPAV--DLGHVDD--FNDS-NYVI
GFAPESK------TTQEIMNKVASAPFM------------------------------KG
RT--IMGWPDEKSTDELDLTY-----STDAVRVIFNDTF-SY----HLKFLWGDRIPKM-
---NE----HRDHSA----------------HCQVM---D-ETITC-------ESSVF--
WEKGFVAFQATINAAIMEIATNHSVMEKLMSVTGINMKILPF---------VAQAGVM--
MDFFIFFCIISFSAFIYYLSVNV-----------TLER-YMKSLMMMMGLQESA------
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---FWLSWGLMY-SGFTFITATLMAL----------I------VILTGFVVVFTLFLLYG
MSLXXXXXXXXX----------------------------XXXXXSLT---GLAV-----
FL-LTVFWGS--------LGFTALYRHLPAFLEWTLCLLSPFAFTAGTAQLIHLDYD---
------GNSNIPLDSSNNQYLIIATLFMLVFDAFLYLALTLYFDKILPTE---YGRRHSP
WFFLKSSFWFQHQRA-DHAA--LENETYVDSS--SDSFEPVSPXXXXXXXXXIRNPRKEY
------------GRGK------Q-----------------------------EKVEALKX
XXX------XXXXXXXXXXXXXXX
PF00005 // ENSGT00760000118965_1_Domain_3 (1705, 1979)
AGKTTLLNAISGLSAPT---GSVTIYNHSLSEMAEP
GTISR-LTGVCPQS--NVQFGFLTARE-NLRFFA-VKGIQPHEVE-QEVQRVLRDLEKEN
IQDILAQHLSGGQKR-KLTLGIAFLGDPQV--LLLDEPTAGSDPLSRHHVWNLLKEK---
---------------KSDRVILFSTQFMDESD----------------------------
--------------------I---------------------------LADRKVFISSGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDSI-TSLVKQH--------------------IPDAKL----AAQNEEKLVYI--LPL
ER--TNKFPDLYRDLDRRSNQ---------GIENY--SVSMT----TLNEVFLKLEGK-S
GVDEP---------DIGIW-GQL-QSDRT--------KDAGSLVELE----QVLSSFN--
----ETKSA-V-----------------------SGMAL-RQQLWAMAKV---------R
LLKLKKE-RRTLLTILLLFGISFCPQLLEHLFYELYQK-CYSWGLSPNMYFLSPEQPP--
QAPLTHLLVI-----NK--TXX-XXXXXXXSLRQQNIAFEVDAFG----TRSG-PDEPSY
D-GAITVT-----DRR---FSIACNTKRLNCFL-VL-LDIISNGLLGIFN----------
----------SSEH--IETDRSTYFEEHTS-------Y-ESGYP-----SSAAFWIPLTA
CFTPYIAMSRVGDYKKKA-HSRLRISG-LCPSAYWFGQ-ALVDVPLF-------------
---FLILLLMQI---VDYNFSPEEV-----LFVIQSLLNVQILYSIGYVSSLIFLTYVIS
FVFRSGRTNSGIWSFFFLII-----TIFPMVATEL---NEYGF-LGLLLCTMLIPPF---
--TLI--------GSLFTFSEIS----------PDS------VDYLGAS-QQIEFLALLI
PYLHFFIFLFVLRCLE-MNFRKKLMRKDPVF-RISPRSSSVLPNPEKPEG----EDDGVQ
MERMRTANAVT-APDSD--ENPVIIASCLRKEYTGRRKTCFAKRK--KKVATRNVSFCVK
E
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVIGLLGHNGAGKSTAIKMITGDTKPTAGQVL-LK--GRGG-------GD----ALGF
LG-CPQENARWPSLTVQEHLEVFAAVKGLRKADAA-----AAITR----LVDALKLQEQL
KLPVKALSEGGK---RKLCFALSLLGNPSVVLLDEPSTG----TDPEG-QLQMWQATRAT
IRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAQVESL
HGEILRVFPHAA--RQERFSSL--MVYRLPLEDVRPLAQAFFKLEAXXXXFDLE---EDS
I-SKSTLEHV----------------------------------------------LLEL
SKEQDLRWFE-EVRDP-SVQWKLPAEP------------------------
ENSVPAP00000000102 (view gene)
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--------------------------------------------------IIRLDYNMYX
XXXXXXXXXXXX----------------------------XXXXXXXX---XXXX-----
XX----------------XXX--XX--X-XX-X-X-X-XX-X--XX-XX-X-XX-XX-XX
-XX-XX-XXX-XX----------XXX-XX-XXX-XXX-XXX-XXX-XXX----XXXX-XX
X-XXXX-XXXX-XXX-X-XX--XX-XXXX-XX-XX-XXXXX-XXXXX-XXXXX-XXXXX-
-------------XXX------X-----------------------------X-XXXX--
--X--XXXXXXXXXXXXXXXXXXXXXX--------XXXXXXX--XXXXXXXXXXXXXXXX
XXXXX-XXXXXXXX--XXX----XXXX-XX---XXXXXXXXXXXX-XXXXX---XXXXXX
XXXXXXXXXXXXXXX-XXXXX-XXXXXXX-----XXXXXXXXXXXXXXXX-X-XXXX---
---------------XXXXX--XXXXXXXXXX----------------------------
--------------------X---------------------------XXXXXXXXXXXX
XXXXXX--XXXXX---XXXXX---XXXX--XLYRN-E----------------------T
CDPEKI-TSFINHH--------------------IPDAKL--K-TESKE-KLVYT--LPV
ER--TNXXXXXXXXXXXXXXX---------XXXXX--XXXXX----XXXXXXXXXXXX-X
XXXXXFEQ--------------A-EM--I--------RDTGSQHEME----PACFSLP--
----ETQK-AV-----------------------SGMRLWRMQFCAIARL---------R
FLKLKHG-KKALLTLLFVFGIAMLPLIAERIHYAVLSQ-KTSWEFKPELYFLSPGQLP--
QDLRTSLLII-----NNTES---DIEDFIQSLKHQNILLEIDDFE----NRNG-TDDPSY
N-GAIIVSGKQ-KAYR---FSVVCNTKRLHCFP-IL-MNVISNGLLRMFN----------
----------HTQC--IRTERSSFPF-------------IYAPFWTGLPEGSFFLFFVVC
SLSPYIAMHSVSDYKR-RSKSQLWISG-LHASAYWCGQ-ALVDVNLY-------------
---NFILLSMYL---TFYVVNLLPI------YLTSRIVFAFAVITFGYAASLVFLTYVIS
FILRERRKNSGLWSFCFYIS-----AV--IVFSILA--EFGSL-PIWIVGMILVPSM---
--TL--------GGFVVFLEER-----------AHKS--EINYPDPNYDLNAADLLVCLI
PYFQALLFIFVLRCLE-IKCGNKIMQKDPVF-RISPKSRDARPNPEEPV----DEDEDVQ
TERIRTATALT-TSIEE--XXXXXXXXXXXXXX-XXXXXXXXXXX--XXXXXXXXXXXXX
X
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
XEILGLLGPNGAGKSSSIRMVSGIMKPTAGEVE-LT--GYDSVL-------------DL
LGYCPQENVLWPTLTAREHLEVFAAVKGLRKADAT-----VTISR----LVEAFKLHEQL
NVPVQKLMAGAT---RKLCFVLSILGNPPILLLDEPSTG----VDPTE-QQQMWQTIQTA
IKNTERGALLTTHHMAEAEAICDRVAILVSGRL---------------------------
---------------------------RFIGSIQHLKNK-LGKDYILELKVKETSQAALV
HTEILRLFPQAA--TQERYSSF--LAYKLPMEDAHPLSQAFHKLEAVKRNFNLE---EYN
L-SHCTLEKV----------------------------------------------FLEL
SKEQEPGDFD-REVDT-TVRWKLLPHSEDP---------------------
ENSTSYP00000027914 (view gene)
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---------------IGIW-GQS-QNDGT--------KDTGSLVELQ----QVLSSLS--
----ETGKT-I-----------------------SGMVLWRQQFFAMARV---------R
FLKLRRE-RKGLLTMLLLFSISFIPHLLEHLFYEFYSK---SWDLAPNKYFLSPGQQP--
QDPLTRLLVI-----NK--TGS-SIDDFIYSLRRQNISLEVDAFG----TRNG-ADEGSY
N-GAIAVSGNE-KDLR---
PF12698 // ENSGT00760000118965_1_Domain_4 (2420, 2771)
FSIACNTKRVNCFP-VL-IEVISNGLLGIFN----------
----------SSEY--IHIDHRTFYEEDLD-------Y-EFGLL-----SAASFWIPMAA
YSVPYIAMSSISDYQTKA-HSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FMILLLTQV---TEHMFN---------IYTLQNML-TKILCDTGYVLSLVFLTYVIS
FISHNGKESSSICSFFFLIT-----IILSIVVTDQ---NGHRL-LGLLFCTILIPPF---
--TLI--------GSLSIINQAF----------SDY------MDYSGTSEFDILHLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-MNFRKKSTRKDPVF-RIPPRSNDVYPNLEEPEG----EDEDVQ
MERMRTADAMT-VPDTE--EQPIIIASCLRKEYSGKKKNCFTKRK--KKVAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCIK
KGEVVGLLGHSGAGKSTVMKMIAGDTKPTAGQVI-LK--GSSG-------ED----TLGS
LGYCPQENALWPNLTVREHLEIYAAVKGLRKGPAT-----IAITW----LADALQLQDQL
KAPVKTLPEGGK---RKLCFLLSVLGNPSVVLLDEPSTG----MDPEG-QRQMWQVIRAT
FRNMEMSALLTTRYLAEAEAVCDRVAVMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLAHVEPL
HAEVLRLFPQAV--RQERLSSL--MVYMLPVEDVQPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFD-EDPGA-SVKWELFSQEEL----------------------
ENSECAP00000020769 (view gene)
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---------------------------MNKRHLSVRQQTWALLCKNVLKKWR-----MKR
ETLMEWFFS-LLLVLFAY-LFSS---NLHQVNDFPQLPAM--DLGRVDN--FNDS-NYVI
AFAPESK------TTQEIMNKMASAPFM------------------------------KG
RT--IMGWPDEKSMDELDFNY-----SVDTVRVIFKDTF-SY----HLKFSWGGRIPKM-
---KE----HRDHSA----------------HCQIM---D-EKITC-------EGSMF--
WEKGFVAFQAAINAAIIEITTNHSVMEELMSVTGINMKILPF---------VAQAGIT--
TDFFIFFCIISFSAFIYYLSVNV-----------TQERQYIKSLMTMMGLRDSA------
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---FWLSWGLMY-AGFIFIMATLMAL----------IVTSAQVVVLTGFMVVFALFLLYG
LSLITLVFLLSV----------------------------LVKKPFLT---GLVV-----
FL-LIVFWGS--------LGFTALYRHLPAFLEWTLCLLSPFAFTAGMAQLIHLDYD---
------INSNIQLNSSNNPYLITATLFMLVFDALLYLILALYFDKILPTE---YGHRHSP
WFFLKSSFWFQHQRA-DHVP--LENETDSASS-PNDSFEQVSPEFYGKEAIRIKNLKKEY
------------GTRK------H-----------------------------EKVEAL--
--K--GLVFDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNMLSGLSAPTS--GSVTIYNHSLSEMADL
ETVSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGIQPHEVE-REVQRVLRDLEMEK
NQDILVQDLSSGQKR-KLTLGIAILGDPQV--LLLDEPTAGSDPLSRHQVWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDSI-TSLVKHH--------------------IPDAKL----TAQSEEKLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIESY--GVAMT----TLNEVFLKLEGK-S
SLDES---------DIGIW-GQL-QSARN--------TDTGRLVELQ----QVLSSFN--
----ETKKV-V-----------------------SGLALWRQQLCAIAKV---------R
FLKLKNE-KKTLLTILLLFGISLCPQLLEHLFYELYQK-SYSWGLSPDMYFLSPAQQP--
QAPLTPLLVI-----NK--TGS-SIDDFIHSLKQQNIALQVDAFG----TRNG-LNESSY
N-GAITVSGDD-KSYR---FSIACNTKRLNCFP-VL-MDIISNGLLGIFN----------
----------SSEH--IQTDRSTYFEKEMV-------L-PLHDL-----HNASFWILVAA
CFTPYIAMSSFGDYKKKV-HSQLRISG-LYPSAYWFGQ-ALVDIPLN-------------
---FLILLLMQI---MDYVFSPDEI-----IFIIENLL-VQILCSIGYVSSLVFLTYVIS
FICRNGRKNSGIWSFFFLII-----TVFSIVATDL---NEYGF-LGLFLCTILIPPF---
--TMI--------GSLFIFSEVK----------VGS------VYRQGQCCEQIVFLALLI
PYLHFFIFLFVLRCLE-MNFRKKSMRKDPVF-RISPRSSDVFPNPEEPEG----EDEDVQ
MERMRTANAMT-VPDFD--EKPVIIASCLQKEYAGKMKNCFAKGK--KKVATRNVSFCVK
KGEVIGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STTIKMITGDTKPTAGQVT-LK--GSSG-------GD----TIGF
LGYCPQENVLWPNLTVKEHLEVFAAVKGLRKEDAA-----VAITR----LVDALKLQDQL
KLRVKALSEGMK---RKLCFALSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKLKTPAQVEPL
HSEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLSQAFFKLEIVKQSFNLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELEDFV-EEVDL-SVNWKLLPQEAP----------------------
ENSRROP00000005135 (view gene)
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---------------------------MSKRCMSVGQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--ITGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMRC-------EGSEF--
WEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGIHMKILPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYIMSLMTMMGLRESA------
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---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LTVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCFWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHTLSGMADI
ENISK-LTGFCPQS--NVQFAFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVQDLEMEN
IQDILAQNLSDGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGNLVELE----QVLSSFH--
----ETRKP-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-GKSLLTILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHTD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FLFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILLPPF---
--TLI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNTVFPNPEEPEG----EEEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GD----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADVLKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSFL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGVLE-DDFNP-SVKWKLLPQEEP----------------------
ENSCATP00000020642 (view gene)
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---------------------------MRKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-
PF12698 // ENSGT00760000118965_1_Domain_0 (551, 1542)
FLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HKDHTA----------------HCYET---S-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHTF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFGLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGRRRSP
LFFPKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTVYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2470)
AGLDPFSRHQVWNLLKER---
---------------KTDHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTESLVEME----QVLSSLN--
----KMGKT-I-----------------------GGMALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMAGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
---------
PF12698 // ENSGT00760000118965_1_Domain_4 (2470, 2719)
-PSVH--IQTERSTFLENGQ-----ANPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNVEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TVFSVAGF-AF--IVFES-DIPFIFTFLIPPA---
--TMI--------GCLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
SSHLL----------FS------SLLSEE-RMDVQPFLVFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDP-SVKWKLLPKEEP----------------------
ENSMLUP00000005048 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MNRKKKNVYQQTQALLCKNLLKKWR-----MKR
ESLLEWGFP-VLLGLYMG--LLS---STKENTQFPGKPSQ--NLGRVDK--YNNSFLF-A
VYTPVSN------ITKQIMNKTVSAPFL------------------------------KE
TT--VIGAPNQKSMDELLENH-----FPRAVGVIFSDTF-SY----ELKFLHSYGIPFL-
---KG-----DHLSA----------------HCWNS---GN-EPSC-------SLTKY--
LSSGFVTLQAAINAAIIEILTDHSVMEELMSVTAINMKTLPF---------IAKDLLQ--
NEMFIFQCLLYFSSFIYFASFGV-----------TKERKKSKDLMKIMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWFSWGLIY-AGFIFIISIFIAM----------IITSRKIIVMTGFMVIFILFFLYG
LSLIALTFLTSV----------------------------LLKKTSLT---NFVV-----
LL-LTLFWGG--------VGLSALHRQLPSSLEWILSIFSPFAFTAGMAQIIHMDYN---
------MNGVTFPDPSGDSYIMIATFFMLAFDAFWYLVLALYFDKILPYG---NERRYSP
LFFLNSSSCFQHQ-RTDN-T--IEKETDLEHT-SDDDFEPMAPEFQGKEAIRIRNIKKEY
-------------KEK------S-----------------------------GKVEAL--
--KETGLLFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSSLLNILNGFSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVHFDILTVKE-NLRLFAKIKGIQPQEVD-QEVQRILLELDIQN
IQDNPAQHLSEGQKR-RLTFGIAILGDPKV--LLLDEPTAGLDPFSRQQVWSFLKER---
---------------KADHVILLSTSLMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SGFLK---RKWGL---GYHLNISLYRN-E----------------------I
CDPERI-TSFINHH--------------------VPDAKL----KTESKEKLVYT--LPA
ER--TDKFPDLFSDLDKGSVQ---------GVVSY--DIAVS----TLNEVFKKVEEI-S
TVEQG----------------FE-QAEM---------RDAESLPQMQ----PAHPPFP--
----------V-----------------------SDLELWRMQICAVARL---------R
FLKLKCG-KKMLLTLLLVFGIALLPLIVELIFDVVLSK-KSQWEFKPGLNFLSPGQLP--
QDPLTSLLII-----NN--TES-NIEDFIQSLKHQNILLEIDDFV----NRNS-TDDLSY
N-GAIIVAGKQ-KDYR---FSVVCNTKGLQCFP-VL-MNIISNALLGMFN----------
----------HTQQ--IRTLRSAFRLNWL-------------FFWTGLPEGSFFLFSVVC
SISPYIAMSSVSDYKKRT-KSQLWTSG-LCPSAYWCGQ-ALVDISLF-------------
---AFFLSSSFL---IFCLENI---QDR---YFTTRLVFASVVIIFGYAASVIFFTYVIS
FIFRKRRKNSGVWSFCFFIT-----SSSLIDLV-II--SHSMS-SASLWIMVFVPSF---
--ALN--------GFLFFMIDRV----------YEHERQNEN---LFYDLSGTDFLVCLI
PYFQALLLAFVLRCME-MKCGQTVMRKDPVF-RISPQRREARPNPEEPID----EDEDVQ
AERTRTATALMTTSSIE--EQPVIIASCLHKEYAGPKKNCFSKKK--KKVVTRNISFCVK
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEVLGLLGPSGAGKSSSLRMISGVTKPTAGEVE-LK--GWNSV-WG---DG----SVKF
LGYCPQENALWPNLTVRVHLDLFAAVKGLRKADAA-----VAITR----LVDAFKLHQEL
NVPVQKLTPGAT---RKLCFVLSILGNSPILILDEPSTG----MDPTG-QQQMWHMIQST
IKNTEKGALLTTQNLVEAETLCDRIAIMVSGRL---------------------------
---------------------------RCIGSIQHLKNK-LGKDYILELKVQEASQVTLV
HTEILKLFPQAA--LQERYSTF--LAYKLPVADVHPLSQAFYKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------LVEL
SKEQTVGNFD-EEVDT-TMRWKLLSHSDDP---------------------
MGP_CAROLIEiJ_P0030733 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MK--ELSVRQQTRALLHKNLLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWSIP-VIIGLHMG--LFS---YLARNIQVLEVPPQ--DLGSLNK--FNGSSLV-V
VYTPISN------ITQQIMNKTTFAPTM------------------------------KG
TR--IIGVPSIEDLDEVFLHN-----IPDALGVIFNDTF-SY----QLKVLRMYGNPFL-
---K------EDSLA----------------HCWDT---YS-EAFC-------SLSKY--
WERGFVALQTAINAAIIEVTTNHSVMEELMAVNAINMKTLPF---------IPRDLSD--
YEIFILFCLLYFSSFIYFASSNV-----------TKERKKCKEVMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIISIFIAI----------IITSTQIIMMTGFLVIFTLFFLYG
LSLIAVTFLTAV----------------------------LLQKAVLT---NLIV-----
LF-FTLFWGC--------VGFTVLHKELPPSLEWALSICSPFAFTSGMAKVIFQDYN---
------LNGVVFPDPSGESYVMIAVFFILAFDALLYLFLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---AEHRSAP
LFFLNPTSCFR-KTANRNKV--IERDLDPEFP-SDEYFEPVDPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTA--GSVTVYNKNLSDMQDL
KEIRK-AIGVCPQH--NVQFDTLTVKE-NLTLFAKIKGILPQDVE-QEVQQILSELDMQN
IQDDLAEHLSEGQKR-RLTFGIATVGDPQI--LLLDEPTVGLDPFSRQRIWGFLKER---
---------------RADRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVLISNGT
LKCTGS--SVFLK---RKWGL---GYHL--SLFMD-E----------------------T
CDSARL-TSFINHH--------------------IPDAKL----KAKTKEKLVYI--LPL
ER--TSEFPEFFSDLDKYSGQ---------GLMNY--EVSMS----TLNEVFMNLEGE-P
NTKQA----------------VE-KREAA--------TDSESLNDLE----VVYPSLS--
----QVQKT-V-----------------------GTMSLWRMQVCAIARL---------R
ILKLKRE-RKAFLIILLLLGIALLPLVIEYVANALLEV-KNNWEFKTDLYFLSPGQLP--
QGLRTSLLVI-----NN--TES-NIEDFLQSLKHQNIVLEVDDFE----NRNA-TNSLSY
N-GAIIVSGRQ-KDYR---FSAVCNTKRLHCFP-IL-MNVISNGILYMFN----------
----------HTQY--IRIKEDIFSSFIV-------------LIWTGIQETCLFILCVIC
SVSPYIAMSSVSDYKKKA-DSQLWISG-LYPSAYWCGQ-AVVDISLF-------------
---SGMLLTCYF---TSYTSKL---LNI---DMTSEIVFSVIVLALGCAASLVFLTYVIS
FVFGKRRKNSSLWSICFLIV-----IAITFDKV-AN--SSFNE-ALVISATMLVPSF---
--ALN--------GLLVILELRA----------YQYYIEFEE---IKHGLSAVDLLLCLI
PYIHTLLFIFVLRCLE-LKYGKSVVRKDPIF-RIAPQSLKGQPNPEEPID----EDENVQ
AERLRTSDALS-APNLD--EKPVIIASCLHKEYTGQKKRCCSRRT--RNVAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVE-LK--RLSSA-VGHQDDS-----RAE
FGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAV-----ITISR----LVNALKLHDQL
NVQVQNLVAGVT---RKLCFALSILGNSSVLILDEPSTG----LDVSG-KQQMWQAIQAA
VKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYVLELRVKDVSQEPLV
HREILKLFPQAA--RQDRCLSL--LTYKLPVTDVHPLSQAFHKLEAVKHGFDLE---DYS
L-SQCTLDRV----------------------------------------------ILEL
SKEQELGAVY-EEADV-TLGRRLLR--------------------------
MGP_CAROLIEiJ_P0030731 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKRHLRLGQQMWALLCKNWLRKFR-----MRR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLLEWLFS-LLLILFVY-QLSS---NLHQVHDAPEMSVV--DLGRVDK--FNDS-NYMM
VFAPESE------ATHEIMTKVASAPFM------------------------------KG
RT--IVACPDEKTMNELDLNY-----SIDAVRVIFKDTF-SY----HLKFSWGQRIPKT-
---KE----HKDHSA----------------PCESL---N-NKMIC-------ENSVF--
WEKGFVAFQAAINAGIIEMTTNHSVMEELMSVIGSNMKMPPF---------IAQGGVA--
TDFFIFFCVISFSSLIYYLSVNI-----------TQERQYMTTLMAMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILVVAVLMSL----------IVKSAQVVVLTGFMVVFLLFLFYG
LSLITLSFLMSV----------------------------LIKKPFLT---GLAV-----
FL-LTVFWGS--------LGFTALYKHLPAFVEWTLCFLSPFAFTTGMAQLIHLDYD---
------VNSNVNLNSPNNSYLIMATLFMLVLDALLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1685)
YFDKITLSK---YGHQRSP
LFFLKSSYWFKRRGA-SHVV--LENEIDSDPS-LNDSLEPASPEFQGKEAIRIKNLKKEY
------------S-GK------H-----------------------------GKVEAL--
--R-
PF00005 // ENSGT00760000118965_1_Domain_3 (1685, 1840)
-GLGFDIYEGQITALLGHSGAGKTTLINTLSGLSPPTT--GSVTIYNQTVSEMDDS
DAVLM-LTGVCPQS--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QEVQQVLRDLEMEN
IQDILAQNLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2434)
AGLDPLSRHRIWNLLKER---
---------------RPGRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LRCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------A
CDPEGI-TSLVKKH--------------------IPDARL----TTQSEERLVYI--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIEDY--GVSMT----TLNEVFLKLEGK-S
MADES---------DVGIC-GRL-QSDGA--------RDVESLVELE----QVL-SLD--
----SSGSS-V-----------------------SGMALWRQQLCAVAKV---------R
FLKLKNE-RKSLMTVLLLFGISFVPQLLEHLVYKVYHK-SYSWGLSPSMYFLSPGQPA--
QDPLTHLLVI-----NR--TGS-SIDNFVHALRQQGIALDLDALG----TRNG-TEEALY
N-GAITVLGEE-KDLR---FSVACNAKRLNCFP
PF12698 // ENSGT00760000118965_1_Domain_4 (2434, 2771)
-VL-MDIISNGLLGTFN----------
----------SSER--IQTDRSTVFEEHML-------Y-EYGFM-----SNAFFWIPVAA
SLTPYIAMGSISDHKKKV-LSQLWTSG-LYPSAYWCGQ-ALVDIPIY-------------
---FLILFLMQI---MDSVFSSEEL-----ITVMESLF-IQIPCSIGYASSLIFMTYVIS
FIFRNGRKNSGIWSFFFLIV-----TIFFIIATDI---NEYGF-LELLICTFLVPPF---
--TLI--------GSLLIFSEVS----------YDS------VDYLEASESQLVFLALLI
PYLHFLLFFF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-RYLRKKSLRVDPVF-RISPRSCHAFPNPEEPGE----EDEDVQ
MERVRTTGAMA-TLQTD--EKPVIIASCLRKEYTGRRKRCFSKTK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVK
KGEVLGLLGHNGAGKSTTISMITGDTIPTAGQVF-LK--GSGG-------GA----ALGF
LGYCPQENVLWPNLTVKEHLELYAAVKGLKKKDAV-----VTISR----LVNALKLQDHL
KALVRTLSEGVK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FTNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTPSQVEPL
NMEIMRLFPQAA--RQERYSSL--MVYKLPVEDVRPLSEAFFKLERLKEDFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFG-EEANS-SVKWKLLPQEEL----------------------
ENSMPUP00000014234 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHMKQKSVYQQTQALLYKNFLQKWR-----MKR
ESLLEWALP-ILLGLYMG--LFS---HFRENMYFPELPPQ--DLGSADH--VNNS-VA-I
VYTPVSE------LTQEIMNKTAFA-LL------------------------------KE
RR--IIGVPNQKSMDKILLDN-----ITGIAGIIFNDTF-SY----KLKFFQGYYIPFL-
---KE-----DLFSA----------------HCWNL---DNEDHSC-------SLSKY--
WSSGFVALQAAINAAIIQITTNHSVVEELMSITAVNMKTLPF---------MYKDVLQ--
KELFIFYCLLYFSPFIYFVSLNV-----------TKERKKCKDFMKIMGLQESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSCGLIY-ATFIFIISIMITV----------IITSTQIIVMTGFMVIFTLFFLYG
LSLIALTFLMSV----------------------------LLKKTLLT---NLVM-----
FL-LNIFCGG--------VGFTVYYRQLPSSLEWILSFCSPFAFTAGMSKIIYLDNT---
------MDGIIFPDPSGDSYVMIATFSVLAFDALFYLALALYFDKILPYG---DERHYSP
LFFLNS-SCFQHQ-RTN-TV--IEKEIEPEPP-SQDCFEPVAPEFQGKEAIRIRNVKKEY
-------------
PF03193 // ENSGT00760000118965_1_Domain_2 (1634, 1718)
TSK------S-----------------------------GKMEAL--
--K--DLFFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTE--GSVTIYNKNLSEMQDLEEIRK-ITGVCPQF--NVQFDILTVKE-NLRLFAKIKGIQPQEVE-QEVQRILLELNIQNIEDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEPTAGLDPFSRHRVWSFLKEH------------------KAGRVILLSTNLMDEAD------------------------------------------------I---------------------------LADRKVIMSNGRLKCAGS--SVFLK---RRWGL---GYHL--SLYRN-E----------------------VCDPEKI-TSFINHY--------------------IPDAKL----KTENKEKLVYT--LPMER--TNKFPDLFSELDKCSGQ---------GVMSY--DISMS----TLNDVFMKLEGK-STIGQD----------------FE-QAE-I--------RGTENLHEIE----PACSSFP------ETQKA-A-----------------------SGMGLWKMQIRAIARL---------RFLKLKRG-KKDLLILLLVFGIAMFPLIVEKIMYALLIQ-KSDWEFKSELYFLSPGQPP--EDPRTSLLII-----NN--TGS-NIEDFIQSVKHQNILLEVDDFA----NRNG-TDDLSYN-GAIIVSGKQ-KDYR---FSVACNTLRLHCFP-IL-VNIISNGLLRLFN--------------------CTQN--IRIERSPYPFNFM-------------IYWTGLPEGSMFLFWVVCSISPYISMSSVSDYKKRA-KSQLWISG-LYPSAYWCGQ-ALVDISFF----------------VFLLLLMYL---IFYIANI---TEI---YITSRIVFSLVVFGLGYATSLVFLTYVISFIFRKWKKNSGLWSFCFYIT-----SIIMFDIV--L--LHFNL-PTLISSMVFIPST-----TMG--------GFLAFLTMRA----------YEHQPKYPD---HKYDPSGVDLLVCLIPYLQALLFVFILRCLE-TKCGKKIMRKDPVF-RISPQRRGARPNPEEPVD----EDEDVKAERQRAATALT-TSQAG--EKPVIIASCLHKEYAGQKKSCFSKRR--KKIAARNISFCVKKGEILGLLGPNGAGKSSSIRMISGISKPTAGE-VELK--GCGLV-WDHQGDN----TVSFPGYCPQENVLWPSLTVREHLEIFAAIKGLRKGDAT-----IAISR----LVDTFKLHGQLDVQVQKLTAGAA---RKLCVVLSVLGNSPVLLLDEPSTG----MDPAG-QQQMWQVIQASIKNTEKGALLATHYLAEAEAICDRIAIMVSGRL------------------------------------------------------RCIGSIQHLKDK-LGKDYFLELRVKEAAQVTCVHTEMLKLFPQVA--PQERYFSF--LVYKLPLADVYPLSQTFRKLEAVKHNFNLE---EYSL-SQCTLEKV----------------------------------------------FLELSKEQELGNFE-EEIDT-TMRLELLSPADDF-----------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SSLLNILNGLSVPTE--GSVTIYNKNLSEMQDL
EEIRK-ITGVCPQF--NVQFDILTVKE-NLRLFAKIKGIQPQEVE-QEVQRILLELNIQN
IEDNLAKHLSEGQKR-KLTFGIAILGDPQI--LLLDEPTAGLDPFSRHRVWSFLKEH---
---------------KAGRVILLSTNLMDEAD----------------------------
--------------------I---------------------------LADRKVIMSNGR
LKCAGS--SVFLK---RRWGL---GYHL--SLYRN-E----------------------V
CDPEKI-TSFINHY--------------------IPDAKL----KTENKEKLVYT--LPM
ER--TNKFPDLFSELDKCSGQ---------GVMSY--DISMS----TLNDVFMKLEGK-S
TIGQD----------------FE-QAE-I--------RGTENLHEIE----PACSSFP--
----ETQKA-A-----------------------SGMGLWKMQIRAIARL---------R
FLKLKRG-KKDLLILLLVFGIAMFPLIVEKIMYALLIQ-KSDWEFKSELYFLSPGQPP--
EDPRTSLLII-----NN--TGS-NIEDFIQSVKHQNILLEVDDFA----NRNG-TDDLSY
N-GAIIVSGKQ-KDYR---FSVACNTLRLHCFP-IL-VNIISNGLLRLFN----------
----------CTQN--IRIERSPYPFNFM-------------IYWTGLPEGSMFLFWVVC
SISPYISMSSVSDYKKRA-KSQLWISG-LYPSAYWCGQ-ALVDISFF-------------
---VFLLLLMYL---IFYIANI---TEI---YITSRIVFSLVVFGLGYATSLVFLTYVIS
FIFRKWKKNSGLWSFCFYIT-----SIIMFDIV--L--LHFNL-PTLISSMVFIPST---
--TMG--------GFLAFLTMRA----------YEHQPKYPD---HKYDPSGVDLLVCLI
PYLQALLFVFILRCLE-TKCGKKIMRKDPVF-RISPQRRGARPNPEEPVD----EDEDVK
AERQRAATALT-TSQAG--EKPVIIASCLHKEYAGQKKSCFSKRR--KKIAARNISFCVK
KGEILGLLGPNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSIRMISGISKPTAGE-VELK--GCGLV-WDHQGDN----TVSF
PGYCPQENVLWPSLTVREHLEIFAAIKGLRKGDAT-----IAISR----LVDTFKLHGQL
DVQVQKLTAGAA---RKLCVVLSVLGNSPVLLLDEPSTG----MDPAG-QQQMWQVIQAS
IKNTEKGALLATHYLAEAEAICDRIAIMVSGRL---------------------------
---------------------------RCIGSIQHLKDK-LGKDYFLELRVKEAAQVTCV
HTEMLKLFPQVA--PQERYFSF--LVYKLPLADVYPLSQTFRKLEAVKHNFNLE---EYS
L-SQCTLEKV----------------------------------------------FLEL
SKEQELGNFE-EEIDT-TMRLELLSPADDF---------------------
ENSOGAP00000002474 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------VKMCRRHMSVVQQTWALLCKNCLKKWR-----TRG
ATFLEWLFS-FLAVLFVY-LRSW---NLHQVYDYHDIPAA--YLGRVDH--FNDS-DYVI
AFAPESN------TTKEIMDKVALAPFIVLFRKFYVKRVIFITVHSKKSYLMTVFFHMAG
RR--ITGWPDEKGMDDLDVDS---------------------------------------
----------------------------------SE---D-VDIMC-------ESLSF--
WERGFVAFQAAINAAIIEVTTNHSVMEQLMSVTGINMKIFPF---------IAQGGVA--
TDFLIFFCVMSFSAFIYYASVSV-----------AQERQYIKSLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATVMAV----------IVKSAQVVVLTGFAVVFLLFLLYG
LSLITLAFLMSV----------------------------LIKKPSLT---GLVV-----
FL-LIVFWGS--------LGFTALYSLLPAFWEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNADAHLNSLHNPHLIIATLFMLVFDTLLYLALTLYFDKILCTE---YGHRRSP
LFFLK-SFWLKHQRP-DHMA--LENEIDSDPS-SDDSFEPVSPEFYGKEGIRIRNLKKEY
------------L-GK------H-----------------------------EKIEAL--
--K--GLVFDIYEGQITALLGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLSVPTS--GSVTIYDHTLSEMTDL
ETVRK-LTGVCPQT--NVQFGFLTVRE-NLRLFAKIKGILPHEVE-QQVQQVLRDLEMEN
IQDILAQNLSGGQSR-KLTLAIAILGDPQV--LLLDEPTAGLDPLSRHRVWNLLKEG---
---------------RSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFMSAGR
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPDRI-TSLVKQH--------------------IPDAKL----TAQSEEKLAFI--LPV
ER--TNKFPDLYRDLDKCSNQ---------GIENY--GVSIT----TLNEVFLKLEGK-S
TLDES---------DLGIW-RQL-QSDGA--------KDVGSLVELE----QVLLPLR--
----EAREA-I-----------------------SGMALWRQQVRAMAKV---------C
FLKLKNE-RKSLWTLLLLLGISLLPQFVRYVFYDLYQK-SDSWELSPNMYFLSPGQSP--
QAPLTHLLVV-----NK--TGS-SIDNFIHSLRQQNIALEVDAFG----TRNG-TDEPTY
N-GAIIVSGDG-KDHR---FSIACNTKRLNCFP-LL-MDILSNGLLRIFN----------
----------SSEH--IQTEGSLFFAEVLWVVISVHKDAGYAYM-----THAFFWIPMAA
CFSPYIATSSITDHNIKA-HSQLRVSG-LYASAYWCGQ-ALVDVLLY-------------
---FLILLLMHT---MDYIFNPEEI-----AFIIQNML-IHIWCSTGYVSSLVFLTYVIS
FISHDGRKNSGLWSFFFLIVSMHRATIFAMLTVDM---NHNGF-LVMLFSTILIPPY---
--TML--------GCLYIFFEVS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSOARP00000015788 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHFSVGQQTRALLGKNFLKKWR-----MKR
ETLSESLFS-CLLVLFAL-LLSS---NLHQVNDFPQLPAV--DLGRVDN--FNDS-DYVI
AFAPESK------TTQEIMNKLASAPFI------------------------------KG
RP--ISGWPDEQSMGELELNY-----SADAVRVIFNDAF-SY----HLKFLWGHRIPTM-
---KE----HGDHSA----------------HCQVM---D-ESVMC-------EGSLF--
WEKGFVGFQAAINAAIIEITTNHSVMEKLMSVTGINMKILPF---------VAQAGVM--
TDFFIFFCVISFSASVCYVSVSV-----------TQERQFMKPVMAVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFISVTAALMAL----------IVACAPVVVLTGFTAVFTLFLLYG
LSLITLAFLTSV----------------------------LVKKPFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRRLPAALEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNIRSDSPNDQYLIIATIFMLAFDALLYLVLTLYLDKILPTE---YGRQQPP
WFFLKSSSWFQRRRA-DHAA--LENDIGPDSP-SNDSFEPVSPEFHGKEAIRIRNLKKAY
------------GRGK------H-----------------------------EKVEAL--
--E--GLVLDIYEGQITGILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
TTLLNILSGLSAPTS--GSVTIYNHSLSEAADL
EYIRK-LTGFCPQA--NVQFGFLTVRE-NLRLFAKIKGIQPHEVE-QQVQRVLQDLEMGN
IQDVLAQNLSGGQKR-KLTFGTAILGDPQV--LLLDEPTAGSDPLSRHRVWNLLRER---
---------------KADHVVLFSTPFMDEAD----------------------------
--------------------V---------------------------LADRKVFMSNGR
LKCAGS--SLFLK---KRWGI---GYHL--SLHLN-E----------------------T
CDPDSV-TSIVKHH--------------------IPDAKL----TAQSEEKLAYI--LPL
ER--TNKFPDLYRDLESCSNQ---------GIENY--GVSMT----TLNEVFLKLEGR-S
AIDES---------GPGVR-EQL-QSGRT--------NATGSLAEPE----QVVSSFS--
----EANSL-V-----------------------SGLALWRQQLCAVAKV---------R
FLKLKSE-KRALLAIFLLFGITFGPQLLEHVSYRLHQK-SYSWGLSPNMYFLSPGQPP--
RAPLTRLLVI-----NR--TGS-SIDDFIHSLRHQNIDLEVDAFG----TRNG-PNESSY
N-GAITVTGDG-KDPR---FSIACNTKRLNCFP-VL-MDIISNGLLGMLN----------
----------SSEH--IQTDRSTYSEEHES-------Y-EHGYL-----GMAFFWIPGVA
CFAPYIAMGSIGDYKKKV-HSQLRISG-LYPSAYWFGQ-ALVDVPLY-------------
---LSILLLMQI---MDYIFSPDES-----VFIIQNLA-VQTLCIIGYVSSLVFLTYVIS
FIFRHGRKNSGIWSFFFLLV-----TLFAIVASYL---NEHGF-LGLFLCTILIPPF---
--TLI--------GVLLIFSEIS----------PDS------VDYLGASEQQVAFLTLLI
PYLHFFIFLFILRCLE-MKFRKKPMRKDPVF-RISPRSSAVFANPEKPEG----EDEDVQ
MERRRTADAVA-APDSE--EKPAIVASCLRKEYAGRKKNCFAKRK--KKVAIRNVSFCVR
KGEVIGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3038)
STAVKMITGDARPTAGQVL-LA--GGSG-------GS----PTGV
LGYCPQESALWPSLTVREHLEVSAAVKGRAARPGAVGLTPPASRR----LADALKLQDQM
ALPAKALPEGAK---RKLSFALSILGSPAVLLLDEPTTG----MDAEG-QLQMWQLIRAS
FRNTARGALLTTHSMAEAEAVCDRVAVMVSGSLR--------------------------
----------------------------CVGSIQHLKSK-FSRGYLLEMKLKSLAQLEAL
HGEVLRIFPQAA--RQERFASL--LVYKLPVEDVHPLSHAFFCLETVKQNFDL---EGYS
L-SQCSLEQV----------------------------------------------FLEL
CKEQEWDNSD-EEVDL-SVKWKLLQEEP-----------------------
ENSCSAP00000000605 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MKKRDISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS-LLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------AAKG
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HKDHTA----------------YCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVV--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLTL----------VIKSTLFIILSGFMVVFSLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAIYLEKILPNE---YGHRRSP
LFFLKSSFWSQTQKA-DHMA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKI
PF03193 // ENSGT00760000118965_1_Domain_2 (1676, 1720)
EAL--
--K--DLVFDIYEGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTIYNNKLSEVADLENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKNIQDVLAQNLSGGRKR-KLTFGIAILGEPQI--FLLDEPTAGLDPFSRHQVWNLLKER------------------KTDRVILFSTQFMDEAD------------------------------------------------I---------------------------LADRKVFLSQGKLKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------VCVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPLER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-STINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN------KMRKT-I-----------------------GGVALWRQQICAIARV---------RLLKLKYE-RKALLALLLILMTGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSYN-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK--------------------PSVH--IQTERSTFLENGQ-----ANPI---GFL-----AYIMFWLVLTSSCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY----------------FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVISFIFHKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NVFES-DIPFIFTFLIPPA-----TMI--------GCLFLSSHLL----------FS------SLFSEE-RMDVQPFLVFLIPFLHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQMERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIATRNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEFLGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQLKSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL------------------------------------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPLHAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYSL-SQSTLEQV----------------------------------------------FLELSKEQELGDFE-EDFDS-SVKWKLLPKEEP----------
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
STLLNILSGLSTPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEVD-KEIQRVLLELEMKN
IQDVLAQNLSGGRKR-KLTFGIAILGEPQI--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMRKT-I-----------------------GGVALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMTGFCPLLVEYTMVNIYYN-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGMVK----------
----------PSVH--IQTERSTFLENGQ-----ANPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNLEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYVI-----TVFSVAGF-AF--NVFES-DIPFIFTFLIPPA---
--TMI--------GCLFLSSHLL----------FS------SLFSEE-RMDVQPFLVFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVCQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIATRNVSFCVR
KGEVLGLLGHNGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
STSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAE-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVRPLAQAFFKLEKVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSMUSP00000020948 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MIKREISVRQQTCALLQKNLLKKWR-----LKR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1541)
SLMEWVSS-LLLLLFLY--WYP---HGHGATDLSSVPTK--DLGRVDS--FRQS-GFMI
GYTPVTS------MTQQIMEKVAATPFM----------------------------A--D
KK--VLGLLDEENIKELTESH------AEIIRVIFSDTF-SY----HLKFQFDQRIPTS-
---RE----LRDHNA----------------HCDGL---Y-EDVNC-------LIAIF--
WKEGFVALQAAINAAIIETTTNHSVMEELLSVSGKFMKIHPF---------VRQEGIL--
TDFFIFTCIISFSPITYYVSINV-----------ARERKRMKGLMMMMGLRDPA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFVFIMALSLAL----------VIKSVQFFILTSFMVVFSLFLLYG
LSMITLAFLMSA----------------------------LVRKSVLT---GLSV-----
FL-LTIFWGS--------LGFTSLYRYLPAPVEWTLSLFSPFAFTLGMAQLLRVDYD---
------LNSNAPPDPASGSNLIIATNFMLVFDAFLYLALM
ENSGT00760000118965_1_Linker_0_3 (1541, 1682)
MYFEKVLPNE---YGHQHSP
LFFLKSSFWLQTRKP-AHVI--LEDGIDPVPS-SGDSFEPVSPEFHGKESIRIRNISKEY
-------------KGK------P-----------------------------NKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPTK--GSVTIYNNNLSEMADL
ENILR-IAGVCPQA--NVQFDFLTVRE-NLRLFAKIRGIPPQDVE-KEVQRVLLELEMKN
IQNILAQNLSGGQKR-KLTFGIAILGDSQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2376)
AGLDPFSRHRVWNLLKER---
---------------RADRVVLFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGR
LKCAGS--SLFLK---KKWGV---GYHL--SLQLK-E----------------------V
CVPENI-TSLVKQH--------------------IPAAKL----SAEGEGKLLYT--LPL
ET--TYRFPELCQSLDSCPGL---------GIENY--GVSMT----TLNEVFLKLEGK-A
SIDEP---------EVDIV-GEG-QTERS--------GDTERLMEME----QTLSSLR--
----ETEK--T-----------------------DGMALWRQQTCAIAKV---------R
LLKLKHE-RKTLLSVLLILVVGICPFLFENISTKIRQS-SYTWELSPHDYFLAPGQQP--
QGMLTQLLII-----NK--TEA-SIDDFIHSVERQ
PF12698 // ENSGT00760000118965_1_Domain_4 (2376, 2752)
NIALEVDASG----TRDG-TDDPSY
N-GALIVSGNE-KNHS---FSFACNTKRLNCFP-VL-MDILSNGLLGMVK----------
----------PSAR--IQTDRSTYLMDET-----IHPL---EDL-----WKTAFWLILTS
ACPPYIAMSSVTDYKNRA-WFQLRVSG-LFPSAYWVGQ-AMVDIPLY-------------
---CFVFLFMSL---MDYLFRFPDT-----MFSIISHV-IQIPCSVGYAISLIFLTYVIS
FISRKGKKNSGIWSLSFYII-----TVFSVAVI-LL--AFDVD-GTQYYIIFLIPPS---
--TLV--------GCLILSLHLF----------IG------QIFEEG--QV
ENSGT00760000118965_1_Linker_4_5 (2752, 2873)
IEPFLVFLI
PFLHVFIFIFTLRCLE-WKFGKKTMRKDPIF-RISPRNNDVYQNPEEPED----EDEDVQ
MERMRTANALV-STSFD--EKPVIIASCLRKEYAGKQKHCLSKKK--AKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEILGLLGHNGAGKSTSLKMISGDTKVTAGQVL-LK--GSRE-------GD----TPGF
LGYCPQENALWPNLTVKEHLEIFAAVRGLRKSHAA-----VAITR----LADALKLQDQL
KSPVKTLSEGVK---RKLCFVLSILGNPSILLLDEPSTG----LDPEG-QQQIWQAIRAI
IKNTDRGALLTTHYMAEAEALCDRVAILVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTLEQVEPL
NTEILRLFPQAS--RQERYSSL--MAYKLPVEAVQPLSQAFFKLEKVKQTFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDGLELEELDS-SIKWKLLPQEEA----------------------
ENSPANP00000016553 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEFATNHSVMEQLMSVTGIHMKMLPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQERQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHMLSGMADV
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPREVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVFSSFH--
----ETRKT-I-----------------------SGMALWRQQVCAIAKV---------R
FLKLKNE-RKSLLAILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGILN----------
----------SSGH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLQISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFSIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIF----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EDEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGG-------GD----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFNP-SVKWKLLPQEEP----------------------
ENSOARP00000015453 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MHMKQKSVYQQTQALLCKNLLKKWR-----MKR
ENLLEWGFL-ILLALHMC--ILS---HLNQNVHFPGMPPQ--NLGRVDK--YNRSFMD-V
VYTPVSN------LTQQIMNTTAFAPVM------------------------------KG
RR--IIGVPDEKSMDEIMLDT-----FSYSVGVIFNDSF-SY----KLKFYRRYYVPIL-
---KE-----DFFTA----------------YCRRT---NINDFSC-------ALEKY--
WKGGFVPLQAAINAAIIQTAANHYVMEELMSVTAVNMKTPPF---------IFKENLQ--
NEMFIFYCLLYFSPFLYFLSLNV-----------TRERKKYKDLMNLMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AAFIFVASIIITV----------IITSTEIIILTGFTVIFTLFFLYG
LSLIALVFLMTV----------------------------LLKKTFLT---SLLV-----
FL-LTLFWGS--------VGFTAFHQQLPSPLKWVFSICSPFAFSAGLNQIIHLDYT---
------MNGVVFPDASGDSYIMIATFSMLTLDALLYLVLALYFDKILPYG---NESHYSP
LFFLNSSSCIQHR-RTGSHV--DEKDVDPEPR-SDDHCEPVAPEFQGREAVRIRNVKKVY
-------------KEK------T-----------------------------GKVEVL--
--K--GLCFDVYEGQITAILGHSGAGK
PF00005 // ENSGT00760000118965_1_Domain_3 (1708, 1840)
SALLRVLSGSSVPTE--GSVTIYNKNLSEMQDL
EEIQK-ITGVCPQF--NVHFDTLTVKE-NLRLFAKIKGIQPKDVE-QEVQRVLLELDIEN
IQDNLATLLSEGQKR-KLTIGIALLGDPQV--LLLDEPTAGLDPFSRHRVWSFLRER---
---------------KAGRVILLSTNLTDEAD----------------------------
--------------------I---------------------------LADRKVILSNGR
LKCAGS--SVFLK---RRWGL---GYHLSLYR--N-E----------------------T
CDPEKI-TSLINHH--------------------IPDAKL----KTESKEKLVYI--LPV
ER--TNKFPDLFGDLDEGCSL---------GVMSY--EVSTS----TLNEVVTKLEGN-S
VAEQD----------------FE-QEEMS--------RDTGRLHEMD----PPCPSAP--
----ETQKA-V-----------------------SVAGLWRLQFWAMARL---------R
FLQLRRG-KKGLLTLLFVFGVAVFPLIVESIFYAVLNE-TTDWEFKPELYFLSPGQLP--
QDPRTSLLII-----NN--TES-NIEDFIQSLKHQNILLEVDDFE----NRNG-TEDPSY
N-GAIVVSGKQ-KDYR---FSVVCNTKRLHCFP-VL-VSVVSNALLRMFN----------
----------QTRR--IRTERSAYPLGHV-------------LLWTGLPQGSFFLFFVTC
SLSPYIAMSSVSDYKKRT-KSQLWVSG-LFPSAYWCGQ-ALVDVSLY-------------
---SLILLAMYL---IFYLANM---VYV---YLTSRVIFALVVMTLGYAASLIFLTYVIA
FIFRKRRKNSGLWSFCFYVV-----TVITFGII-ML--FAPDV-PVLITCMTLVPSA---
--TLS--------GFTAFLQQRI----------SQYWMKYQE---ANYDLSAADFLVCLI
PYFQALLFMFVLRCLE-AKCGKNIMRKDPVF-RISPQSRDARSNTEKPVA----EDEDVQ
AERIRTATALN--TSIE--EKPVIIASCLHKEYAGQKKRCFSRRR--KKTAVRNISFCVK
KGEILGLLGPSGAGK
PF00005 // ENSGT00760000118965_1_Domain_5 (2896, 3037)
SSSVRMISGMTTPTAGEVE-LT--GYGSD-PGQQGDA----SIRF
LGYCPQENVLWPSLTTRDHLEVFAAVKGLQRADAR-----VAISR----LVDAFKLQEQL
NVPVQKLPGGAA---RKLCFVLSLLGDPPILLLDEPSTG----LDPTE-QKQLWQTIQRA
VRNTARGALLTTHSMAEAEAVCDRVAVMVSGRL---------------------------
---------------------------RCIGSIQHLKNS-LGKDYILELKLKEASQGMSV
HTEVLRLFPQAA--QQERYSSF--SAYRLPVQDVQPLSQAFHKLETVKRNFNLE---EYS
L-SQCTLEKV----------------------------------------------FIEL
SKEQELGNVD-EEVDT-TMRWKLLCPSEGP---------------------
ENSMLUP00000019810 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRERSVCQQTWALLCKNLLRKWR-----MKR
ESLMEWLSL-LLLLLSWY--IHP---ISHEATDFSSLPTM--DLGRVDS--FNLS-TYTI
AYIPLTN------ITQQIMKKVALASLI-----------------------------N-E
TD--VLGLSDEESIEELRENS-----PREVVVVIFTNIS-SY----NLEFSWYKPVSIR-
---KE----HRHHTA----------------HCYET---YREDIDC-------GITTP--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKIHPF---------VSQGGTT--
MDIYLLFFLISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRHSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIATLLLVL----------IIKSIQFVIWTGFMVVFTLFFLYG
LSLIALAFLMSV----------------------------LIKKPFLT---GLVM-----
SL-LTVFWGS--------LGFTVLYRHLPASLEWILGFLSPFAFMLGMTQLLRVDND---
------VNSNAFPAFSNYSSQTIAAHFMLAFDIFLYLALTIYFEKILPNE---YEHQYSP
LFFLKSSFWSRQRNA-DHVA--LEDEIYSDPS-SNDSFEPVSPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKVKAL--
--K--DLAFDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAILGHSGAGKSTLLNILSGLSVPTK--GSVTMYSNKLSEMADL
ENISK-LTGICPQY--NVQFDYLTVRE-NLRLFAKIKGIPPQEME-QEIQRVVLELQMDS
IEDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPTAGLDPFSRHQVWNLLKER---
---------------KMDRVIVFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------M
CVQEKI-TSIVTKH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYENLDLCPDL---------GIENY--GVSMP----TLNEVFLKLEGK-S
TVDEP---------GIATS-GEV-HAEGA--------EDTERLCEME----QVLSSLS--
----EMKER-L-----------------------GGMALWRQQICAIARV---------R
LLNLKQD-RKSLLSLLLILGIGVFSVLWDYIIFSTYDV-SYTWELSPHLYFLAPGQPP--
HDPLTQLLII-----NN--TGA-SIDDFIHSVELQNIALEVDASG----NRNG-IDDPSY
N-GAIIVSGHD-KNYT---FSLACNTKRLNCFP-VL-MDIVSNGLLRIVR----------
----------PSAR--IQTGRSTSLLVSMYSMTPSSGI---SWV-----AGI---LFLLS
K-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSPCOP00000011264 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------EVTTNHSVMEELTS
PF12698 // ENSGT00760000118965_1_Domain_0 (812, 1542)
VIGINMRILPF---------TSKGEVI--
NELFIFICVVCFSSFIYFTSLNI-----------TNERKKFKKLMTVMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-TGFIFIMSIFMVL----------IITSIPIIVHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIKKPLLS---GLAG-----
FL-FTVFWGC--------LGFTVLHRQLPLPLEWVLGLLSPFAFTAGMAQITYLDYY---
------LNGVIFPDPSGDSYFMIVTFFILAFDTLLYLLLTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1688)
YFERVLPDK---DGHRHSP
LFFLKSSFWSKHQ-NTHHEV--FQNEINPEHF-SDDSFEPVNYVTM--------------
----------------------------------------------------KFYQSG--
--S--GI
PF00005 // ENSGT00760000118965_1_Domain_3 (1688, 1840)
FLDIYEGQITAILGHSGAGKSTLLNILSGLSISTE--GSVTIYNTQLSELSDI
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRLFAKIKGIQPKEIE-QEVKRIIMELDMQN
IQDVIAKKLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPFSRHRVWNLLKER---
---------------KVDRVILVSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFLFNGK
LKCAGS--SLFLK---RKWGI---GYNL--SLHRN-E----------------------M
CDTERI-TSLIKQH--------------------VPDAKL----IAESEEKLVYS--LPL
ER--TNKFPDLYSDLDKCSDQ---------GIMNY--GISMT----TLKEVFLNLEGK-S
TIDEP-----V--VNFGIG-KQE-KIKVT--------RDTGNESEVQ----QALCSLP--
----EMRKA-V-----------------------RNGTLWRRQVCAIARL---------R
FLKLRHE-RKTLLSLSLILGVAFIPSIIEKVMYGVGHH-IPRWELSPSMYFLSLKQLP--
KPSLTSLLII-----NN--TGS-NIEDLIHSLMHQDIVLEIDDFS----NRNG-SDDPSY
N-GAIIVSGDQ-KDYS---FSVACNTKKMNCFP-VL-MGIVSNALLGLFN----------
----------SMDL--IQTERNVFPHVSI-------------ILTY--IRGTSTIPFQLK
IQTP--AVSLLFLYQKKT-QFQLWISG-LCPSAYWCGQ-ALVDIPLY-------------
---CLILLSIQL---TSYSVFL----GF---KFPWKFTIVSCTFMLICXXXXXXXXXXXX
X--------------------------------------------XXXXXYPIFPG----
--------------F---------------------------------------------
------------------------------------------------------------
-------------------FSPMYIVICFV---------------------KDQLAVCGW
FC
PF00005 // ENSGT00760000118965_1_Domain_5 (2883, 3037)
EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVV-LQ--DSRA-SVRQQEDH----SPKF
LGYCPQENSLWPSLTMKEHLELYAAVNGLSKEDAA-----LSISR----LVEALQLQEQL
KIPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPKG-QQQIWEAIKNI
IKNKERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGPIQHLKSK-FGKDYLLEIKMKEPTQVEPL
HTEILKFFPQAY--LM---------GFKLLCIIYKPLM--SVPLNAVKHSFDLE---EYS
L-SQATLEQI----------------------------------------------FLEL
SKEQELENFD-DEVDT-TVRWKLLSHEEP----------------------
ENSOPRP00000010568 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHRSVGQQTWALLGKNCLKKWR-----RKR
DTLLEWFFS-FLLVLFAY-LFSL---NLHQVHDSSQMLAV--DLGCVDT--FNES-NYLI
LFAPESK------TTREIMKKVASAPFM------------------------------KG
RT--VMGWPDDKSMNELDLND-----SIDAVRVIFNDTF-SY----HLKFSWGHRIPKI-
---KE----HRDHAA----------------HCQVM---D-EKVMC-------ESSIF--
WEKGFVAFQAAINAAIIEITTNHSVMEKLMSVTGVNMKILPF---------VAQGGVA--
TDFFIFVCIISFSAFIYYITVSV-----------TQERQNMKPLMKMMGLQESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWALMY-TGFISITAIVMTL----------IIKSAQVVVLTGSVVVLALFLLYG
LSLITLAFLMSV----------------------------LIKKPSLA---GLVI-----
FL-LIVFWGS--------LGFTALYRHLPEFLEWSFCLVSPFAFTAGMAQLIHLDFD---
------VDSEISLKSSNHPNLIAANLFMLIFDSLLYLALTLYFDKILPTA---YGHQHSP
LFFLKSSCWFQHQRP-NHMV--LENEVDSDHL-CNDSFEAVPPEFHGKEAIXXXXXXXXX
------------XXX----------------------------------------XXXXX
XXX--XLMLDIYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITALLGHSGAGKTTLMHTLSGLSVPTS--GSVTIYGHTPSEMTGV
ETALK-FIGMCPQS--NVQFDFLTLRE-NLWLFAKIKGILSHEVE-QEVQRVLRVLDMEN
LQDTLARTLGGGQKR-KLTLGIALLGDPEI--LLLDEPTAGLD-LSRHRVWDLLKEK---
----------------SGKAILFSTQFMDEAD----------------------------
--------------------T---------------------------LADRKVFISNGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------I
SDPENI-TTLIKRH--------------------IPDAKL----AAQSEEKRVYI--LPL
ER--TYKFPELYRDLDQCCNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIDESXXXXXX--XXXXXX-XXX-XXXXX--------XXXXXXXXXX----XX--XXX--
----XXXXX-X-----------------------XXXXX-XXXXXXXXX-----------
--XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXQR-S-YSGLSPQMYFLSPGQQV--
QDLLTRLLII-----NR--TGS-SIDNFIHSLWRQNIALEVDAFG----VRNG-ADESAY
N-GAITVSGDA-KDYR---FSIACNTKRLNCFP-VL-MDVISNALLGMLN----------
----------SSEH--IQTDRSTFFEHY-----------EYGYL-----SNAFFWIPVTA
CFTPYLAMSSISDYRQNT-YSLLWVSG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYVFNPDDI-----IYIIQNLL-IQILCSIGYVSSLVFLTYVIS
FICRKGRKNSGAWSFLFLII-----TIFSIVATDL---NEYRF-LGLLFSTLLIPPF---
--TLI--------GSLFIFSEIS----------HDS------MDYLGASESQIVFLALLI
PYLHFFIFVFVLRYLE-KNFRKKSMRMDPVF-RISPQRSKVLPNPEDPEG----EDEAVQ
LERMRAANAVT-LPDAD--ETLVIAASCLRKEYAGRKKHCLSRKK--KTIATRNVSFCVK
R
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEILGLLGHNGAGKSTTIKMIIGDTKPTAGQVI-LK--GSSR-------GE----PLGF
LGYCPQENALWPNLTVQEHLEVYAAVKGLKKREMA-----VTMTR----LLDAFKLQDQG
KAPIKTLPEGAK---RKLCFLLSILGGPSVVLLDEPSTG----MDPEG-QLQLWQAIRAT
FRNTEGGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMQVKTLTQVEYL
HEEILRLFPRAA--RQERYPSL--LVYKLPVEDVQPLSQAFFKLETVKQNFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDAFD-EELDP-SVTWKLLSQEEP----------------------
ENSMOCP00000014374 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------IKEMSVYQQTCVLLHKNLLKKWR-----GRR
ESF
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWSIP-IIIGLYMG--QFS---FFKENMQLPEIPPQ--DLGSLDE--FNGSSIM-V
FYTPVSN------ITQQIMNKTTFSPTM------------------------------KG
TR--IIGLPSKKDLDNMLLKN-----IPHALGIIFNDTF-SY----KLEVFLSHGYPFL-
---K------EDILA----------------HCWDM---RG-DVSC-------SLSRY--
WKKGFVPLQTAINAAIIEITTNRSVMEKLMSVNAISMKTLPF---------ITKDTFQ--
YEFFIVFCLLYFSSFVYFISRNV-----------TNERKKSKELMKMMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIASIFIAV----------IITSAQIIVMTGFPVIFTLFFLYG
LSLIAVAFLMAV----------------------------LFQKAILT---NLIV-----
FL-FTLLWGC--------VGFTVLNKQLPTSLEWILSICSPFAFTSGMAKIIFLEYD---
------LNGVVFPDPSGESYAILVTFSILAFDGLFYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILLYG---EERRYSP
LFCLNLSSCFR-QKTGSHQV--IERGIDPELP-SDDYFEPVAPEYQGKEAIRIRNIKKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1839)
-K--GLFFDIYESQITAILGHSGAGKSSLLNILNGLYVPTS--GLVTVYNKNLSEMQDL
KEIRK-ITGVCPQH--NVQFGALTVKE-NLTLFAKIKGILPQRVK-QEVQQIILELDMQS
IQDNLAEHLSEGQKR-KLTFGIATLGDPRI--LLLDEP
ENSGT00760000118965_1_Linker_3_4 (1839, 2349)
TVGLDPFSRQRVWSFLKER---
---------------RANRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKAIMSNGS
LKCIGS--SVFLK---SKWGL---GYHL--SLSMD-E----------------------T
CDSEQI-TAIINHH--------------------IPDAKL----KAKTHEKLEYV--LPL
GR--TSKFPDFFSDLDKYSGQ---------GLMNY--EVSMS----TLNEVFMNLEGE-S
TTNLN----------------FE-KRETV--------RDSDSLNEME----PAYSSLS--
----EVQKT-V-----------------------SAMTLWRMQVCAIARL---------R
ILKLKRE-RKAFLTFLLILGIALLPLIMEKTANALIEQ-KSDWEFKTELYFLSPGQLP--
QGLRTSLL
PF12698 // ENSGT00760000118965_1_Domain_4 (2349, 2736)
VI-----NN--TGS-NIEDFIQSLKHQNIVLEVDDFA----NRNG-TESLSY
N-GAIIVSGRQ-KDYR---FSVVCNTKRLHCFP-IL-MNVISNGILHMSN----------
----------HTQH--IRTEESVISPDLM-------------MLWFGILQGFLFLLLVVC
SISPHIAMSSVGDYKKKA-DSQLWISG-LYPSAYWCGQ-AVVDINLF-------------
---NVILLLSYF---TLYITQL---VHI---SLTSGIVLSIIALSFGCAASLVFLTYVIS
FVFGKRRKNSGLWSICFFTI-----FTIMFDIL-LT--DLLSE-KLLIAFMILVPSF---
--SFS--------AFPIVLEMRD----------YQ
ENSGT00760000118965_1_Linker_4_5 (2736, 2873)
YYDEFGE---LKYGSSGVDLLSCLI
PYFHTLLFLFALRCLE-LKYGKNVMWKDPIF-RISPKNPKVQPNPEEHRSED--EDEDVQ
AERIRTSAALS-TSNLH--ERPVIIANGLHKEYAGQKRSCFPKRT--KKVAA
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPNGAGKSSSIRMIAGITKPAAGEVE-LK--GVSSP-VGYQGDG-----TVK
FGYCPQENVLWPVLTVKEHLEVYAAVKGLRKEDAA-----IAISR----LVNAFNLHGQL
NVLVRRLAAGAT---RKLCFVLSILGNSSVLILDEPSTG----LDVPG-KQQIWQAVKAA
AKDNEVGVLVTTHDLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKRK-FGKDYILELKVNETSQVASV
HREMLELFPQAA--RQESYLSL--LTYKLPITDVYPLSQAFYKLEAVKCSFNLE---EYS
L-SQCTLDKV----------------------------------------------FLEL
SKEQELENVH-EETDT-TVRWKLLPHLDEP---------------------
ENSGGOP00000004090 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMALASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEMVGVIFSDTF-SY----RLKFNWGYRIPVI-
---KE----HSEYTE----------------HCWAV---HGEI-FC-------YLAKY--
WLKGFV
PF12698 // ENSGT00760000118965_1_Domain_0 (787, 1542)
AFQAAINAAIIEVTTNHSVMEELTSVIGINMKIPPF---------ISKGEIM--
NEWFHFTCLVSFSSFIYFASLNV-----------ARERGKFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---LWLSWGLTY-ICFIFIMSIFMAL----------VITSIPIVFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFTAGMAQITHLDNY---
------LSGVIFPDPSGDSYKMIATFFILAFDTLFYLIFTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGRGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINPEHS-SDDSFEPV-----------IRNVKKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSATIYNTQLSEITDM
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVKRIIMELDMQS
IQDIIAKKISGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2514)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
CDTEKI-TSLIKQH--------------------IPDAEL----TTESEEKLVYS--LPL
EK--TNKFPDLYSDLDKCSDQ---------GIRNY--AVTMT----ALNEVFLNLEGK-S
AIDEP---------DFDVG-KQE-KIHVT--------RNTGDESEME----QVLCSLP--
----ETRKA-V-----------------------SSAALWRRQIYAVATL---------R
FLKLRRE-RRALLCLLLVLGIAFIPIILEKIMYKVTRE-THCWEFSPSMYFLSLEQIP--
KMPLTSLLIV-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNCFP-VL-MGIVSNALMGIFN----------
----------FTEL--IQTESTSFSRDDI-------------VLDLGFLDGSI
PF12698 // ENSGT00760000118965_1_Domain_4 (2514, 2771)
FLLLITN
CISPFISMSSISDYKKNV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILFSMHL---IYYFIFL----GF---QLSWELMFVLVVCIIGCAVSLIFLTYVLS
FIFRKWRKNNGFWSFGFFII-----LICVSTIM-VS--TQYEK-LNLILCMIFIPSF---
--TLL--------GYVMLLIQLD----------F--MRNLDSLDNRINEVNKTILLTTLI
PYLQSVIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
VIRCLE-MNQNCIFMLFYFLC-RISPRSRETHPNPEEPKE----EDEDVQ
AERVQAANALT-APNLE--EEPVITASCLHKEYYETKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVV-LQ--GSRA-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDGA-----LSISR----LVEALKLQEQL
KAPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGTLLTTHYMSEAEAVCDRMAMMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVEAL
HTEILKLFPQAA--WQERYSSL--MAYKLPVEDVHPLSQAFFKLEAMKQTFNLE---EYS
L-SQATLEQI----------------------------------------------FLEL
CKEQELGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSRNOP00000065682 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MGSMKELSVRQQTRVLLHKNLLKKWR-----MKR
ES
PF12698 // ENSGT00760000118965_1_Domain_0 (543, 1542)
LLEWSIP-VVIGLYMG--LFS---YFKENNQVPEVPPQ--DLGSIDE--FNGSSIM-V
VYTPISN------VTQQIMNKTITAPTM------------------------------KG
TR--IVGVPSEKDLDEMLLDH-----VPRAFGIVFNDTF-FY----KLKVYLMYGNPFL-
---K------EDLLA----------------HCWDT---YP-HVFC-------SLTRY--
WKRGFVALQTAINAAIIEVTTKHPVMEELMSVNAFNMKTLPF---------ISKDIFQ--
YEIFILFCLLYFSSFIYFASRSV-----------TKERKHSKEFMKVMGLQDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-VGFIFIFSVFIAV----------IITSTRIIVMTGFLVIFTLFFLYG
LSVIAVTFLMAV----------------------------LLQKAIIT---NLFV-----
FL-FNLFWGC--------VGFTVLHKELPSSLEWVLSICSPFAFTSGMTKIIFLEYN---
------LNGVVFPDPSGESYVMIAVFFILAFDGLLYLVLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPCG---ADRRAAP
LFFLNPVSCFR-KRTSRNKV--TERDIDPELP-SDEYFEPVDPEYQGKEAIRIRNIRKEY
-------------KGK------S-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLFFDVYESQITAVLGHGGAGKSSLLNILNGLSVPTS--GLATVYNKNLSEMQDL
KEIRK-MIGVCPQH--NVQFDALTVKE-NLTLFANIKGIVPQSVA-QEVQQILSELDMQT
IQDELAEHLSEGQKR-KLTFGVAILGDPRI--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2295)
AGLDPFSRQRVWGFLKER---
---------------RADRVILFSTQFTDEAD----------------------------
--------------------I---------------------------LADRKVILSNGA
LKCTGS--SVFLK---RKWGL---GYHL--SLFMN-E----------------------T
CDSEQL-TSFINHH--------------------IPGAKL----KAKTKEKLVYT--LPL
EK--TSKFPEFFSDLDKYSGQ---------GLMNY--EVSMS----TLNEVFMNLEGE-P
STTQD----------------FE-KGETL--------TDSDSLNEME----VAPPSLS--
----KAQKT-M-----------------------SAMSLWRMQVCAIARL---------R
VLKLRRE-RKAFLT
PF12698 // ENSGT00760000118965_1_Domain_4 (2295, 2741)
FLPLLGISLIPLITEYMANALIEV-KTNWEFKTDLYFLSPGQLP--
QGLRTSLLVI-----NN--TES-NIEDFVQSLKHQNIVLEVDDFE----NRNA-TESLSY
N-GAIIVSGRQ-KDYR---FSAVCNTKRLHCFP-IL-MNVISNGILRMLN----------
----------HTQH--IRLEEDVLSSGIV-------------VVWFGILEASLSILFIVC
SVSPHIAMSSISDFKKKA-DSQLWISG-LYPSAYWCGQ-ALVDITLL-------------
---SGILLTGYI---TLYTTKL---MHI---YLTGEIVLSIVLLAFGCAASLVFLTYVIS
FVFGKKRKNSGLWSICFFIV-----ITIMFDTV-LM--DPFNE-ALLISAMMLVPSF---
--SLN--------ALLIVLEMRA----------YQYYREF
ENSGT00760000118965_1_Linker_4_5 (2741, 2873)
GE---SKYGLSGVDLLLCLI
PYFHTLLFIFVLRCLE-LKYGKNVVRKDPLF-RIAPQSLHVQPNPEEPVD----EDEDVQ
AERMRTSDALS-TVNLD--EKPAIIASCLHKEYTGQKKWCCSKRR--KKIAV
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFCVN
KGEILGLLGPEGAGKSSSLRMIAGIMKPTAGEVE-LK--ELSSA-VAHQGEG---HGAAK
LGYCPQENVLWPILTVKEHLEVYAAVKGLRKKDAV-----IAISR----LVNAFKLHDQL
NVQARNLVVGLT---RKLCFALSILGNSPVLILDEPSTG----LDVSG-KQQMWQAIQAA
VKDNKKGVLLSTHDLAEAEALCDRAAIMVSGRL---------------------------
---------------------------RLIGSIQHLKRR-FGKDYILELRVKEISQEPLV
HKEILRLFPQAA--RQDRCFSL--LTYKLPVTDVHPLSQAFHKLEAVKRGFNLD---DYS
L-SQCTLDRV----------------------------------------------FLEL
SKEQELGDVH-EEADI-TMRWKLLPPSDEL---------------------
ENSMMUP00000024481 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MNKMASASFM------------------------------KG
RT--VIGTPDEETMDIVLPKK-----YHEVVGVIFRDTF-SY----QLKFNWGYRIPAI-
---KE----HTENTE----------------HCWAM---HGEI-FC-------YLAKY--
WLNGF
PF12698 // ENSGT00760000118965_1_Domain_0 (786, 1542)
VAFQAAINAAIIEVTTNHSVMEELTSVIGINMKMLPF---------ISKGEIM--
NEWFLFTCLVSFSSFIYFASLNV-----------A--RGEFKKLMTVMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLTY-VCFIFVMSIFMAL----------IITSIPIIFHTGFMVIFTLFSLYG
LSLIALAFLMSV----------------------------LIRKPMLA---GLAG-----
FL-FTVFWGC--------LGFTVLYRQLPLSLGWVLSLLSPFAFIAGMAQITYLDNY---
------LS---------------ATFFILAFDALFYLILTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFERVLPDK---DGHGDSP
LFFLKSSFWSKHQ-NTHHEI--FENEINSEHS-SDDSFEPVSPEFHGKEAIRIRNVRKEY
-------------NGK------T-----------------------------GKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTE--GSTTIYNTQLSEITAV
EEIRQ-NIGFCPQF--NFQFDFLTVRE-NLRVFAKIKGIQPKEVE-QEVEEYIKIDDMQS
IQDIIAKKLSGGQKR-KLTLGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2512)
AGLDPFSRHRVWSLLKEH---
---------------KVDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------M
FS-------------------------------------------TESEEKLVYS--LPL
EK--TNRFPDLYSDLDKCSDQ---------GIRNY--GVSMT----TLNEVFLNLEGK-S
AINEP---------DFDIG-KQK-KIYVT--------RNTGNESEME----QVLCSLP--
----ETRKA-V-----------------------SSATLWRRQIYAVATF---------R
FLKLRRE-RRVLLCLSLVLGVAFIPIILEKIMYKVIRE-THCWEFSPSMYFLSLEQIL--
KTPLTSLLII-----NN--TGS-NIEDLVHSLKRQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKLNCFP-VL-MGIVSNALIGIFN----------
----------FTEL--IQTESTSFSHDDI-------------VLDLGFIDG
PF12698 // ENSGT00760000118965_1_Domain_4 (2512, 2769)
SVFLLLITN
CISPFIGMSSINDYKKKV-QSQLWISG-LWPSAYWCGQ-ALVDIPLY-------------
---FLILLSIHL---IYYFIFL----GF---QLSWELVFVLVVCIIGCAASLIFLTYVLS
FIFRKWRKKNGFWSFGFFII-----LICVSTIL-VS--TQYET-PNLILCMIFIPSF---
--TLL--------GY------FS----------LMYMRNLDSLDSRINEVNKTILLTTLI
PYLQSLIF
ENSGT00760000118965_1_Linker_4_5 (2769, 2873)
LFVIRCLE-MKYGNEIMNKDPVF-RISPRSRETHPNPEEPEE----EDEDVQ
AERVQAANTLT-TPNLT--EEPVITASCLHKEYYDTKKSCFSTRK--KKIAI
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVLGLLGHNGASKSTSIKMITGYTKPCAGVVV-LQ--DSRT-SVRQQHDN----SLKF
LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAA-----LSISR----LVEALKLQEQL
KVPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPFTG----MDPEG-QQQMWQILQAT
VKNKERGALLTTHYMSEAEAVCDRVAIMVSGTL---------------------------
---------------------------RCIGSIQHLKNK-FGKDYLLEIKMKEPTQVKAL
HTEILKLFPQAA--RQERYSSF--MAYKLPVEDVHPLSRAFFKLEAVKQTFNLE---EYS
F-SQATLEQV----------------------------------------------FLEL
CKEQEMGNVD-DKIDT-TVQWKLLPQEDP----------------------
ENSMLEP00000030687 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSNRCMSVSQQTWALLCKNCLKKWR-----MKR
QTL
PF12698 // ENSGT00760000118965_1_Domain_0 (544, 1542)
LEWLFS-FLLVLFLY-LFFS---NLHQVHDSPQMPSM--DLGRVDN--FNDT-NYVI
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGWPDEKSMDELDLNY-----SIDAVRVIFTDTF-SY----HLKFSWGHRIPMM-
---KE----HRDHSA----------------HCQAM---N-EKMKC-------EGSEF--
WEKGFVAFQAAINAAIIEFATNHSVMEQLMSVTGIHMKMLPF---------VAQGGVA--
TDFFIFFCIISFSTFIYYVSVNV-----------TQEKQYITSLMTMMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLMY-AGFILIMATLMAL----------IVKSAQIVVLTGFVMVFTLFLLYG
LSLITLAFLMSV----------------------------LIKKPFLT---GLVV-----
FL-LIVFWGI--------LGFTALYTHLPAFLEWTLCLLSPFAFTVGMAQLIHLDYD---
------VNSNAHLDSSHNPYLIIATLFMLVFDTLLYLALTL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTE---YGHRCSP
LFFLKSCYWFQHGRA-NHVV--LENETDSDPT-PNDSFEPVSPEFCGKEAIRIKNLKKEY
------------A-GK------H-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-R--GVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTS--GSVTVYNHMLSGMADV
ENISK-LTGFCPQS--NVQFGFLTVKE-NLRLFAKIKGILPHEVE-KEVQRVVRDLEMEN
IQDILAQNLSGGQNR-KLTFGIAILGDPQV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2397)
AGLDPLSRHRIWNLLKEG---
---------------KSDRVILFSTQFIDEAD----------------------------
--------------------I---------------------------LADRKVFISSGK
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------R
CDPESI-TSLVKQH--------------------ISDAKL----TAQSEEKLVYI--LPL
ER--TNKFPELYRDLDRCSNQ---------GIEDY--GVSVT----TLNEVFLKLEGK-S
TIDES---------DIGIW-GQL-QTDGA--------KDIGSLVELE----QVFSSFH--
----ETRKT-I-----------------------SGMVLWRQQVCAIAKV---------R
FLKLKNE-RKSLLAILLLFGISFIPQLLEHLFYESYQK-SYPWELSPNTYFLSPGQQP--
QDPLTHLLVI-----NK--TGS-SIDNFLHSLRRQNIAIEVDAFG----TRNG-TD
PF12698 // ENSGT00760000118965_1_Domain_4 (2397, 2771)
DPSY
N-GAIIVSGDE-KDHR---FSVACNTKRLNCFP-VL-LDVISNGLLGIFN----------
----------SSGH--IQTDRSTFFEEHMD-------YE-YGYR-----SNTFFWIPVAA
SFTPYIAMSSISDYKKKA-HSQLRISG-LYPSAYWFGQ-ALVDVSLY-------------
---FLILLLMQI---MDYIFSPEEI-----IFIIQNLL-IQILCSIGYVSSLVFLTYVIS
FIFRNGRKNSGIWSFFFLIM-----VIFLIVATDL---NEYGF-LGLFFGTILIPPF---
--ALI--------GSLFIFSGIS----------PDS------MDYLGASESEIVFLALLI
PYLHFLIFLF
ENSGT00760000118965_1_Linker_4_5 (2771, 2873)
ILRCLE-TNCRKKLMRKDPVF-RISPRSNAVFPNPEEPEG----EDEDIQ
MERMRTANAMA-VRDFD--ETPVIIASCLRKEYAGKKKNCFSKRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSGR-------GD----PLGF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAT-----IAITR----LADALKLQDQL
KAPVKTLSEGIK---RKLCFMLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQVIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERFSSL--MVYKLPVEDVRPLSQAFFKLEIVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
AKEQELGDLE-DDFNP-SVKWKLLPQEEP----------------------
ENSCLAP00000010890 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHISVGQQMWTLLCKNCLKKWR-----MKR
E
PF12698 // ENSGT00760000118965_1_Domain_0 (542, 1542)
TLMEWFFS-FLLVLFAF-LFSS---DLHQVNDSSQMPSM--DLGRVDN--FNDS-NYII
AFAPASK------TIQEIMSKVASAPFM------------------------------KG
KT--IMGWPDEKSMSELDLNY-----SVDAVRIIFNDMF-SY----HLKFSWGHRIPKV-
---KE----HKDHSA----------------HCQVV---D-EKLTC-------ENSVF--
WEKGFVAFQAAINAAIIELAVNRSVMDALMSVTGVNMKTLPF---------IAQGGIT--
TDFFIFFCIISFSSLICHLSVNV-----------SKERQYIKPLMTMMGLRQSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGFMY-SGFILVMAILMAL----------IVKSTQIVVLTGFTVVFILFFLYG
LSLITLAFLMSV----------------------------LIKKPHLT---GLAI-----
FL-LIIFWGS--------LGFTALYRHLPAFLEWILCLLSPFAFTAGMAQLIHLDYD---
------VNSNVHLDASNNSYIIIAILFILVFDAVFYLALTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFDKILPTR---YGHQHSA
TFFLKSAFWCQYRGT-KHVA--LENEIDSDPS-SSDSFEPVSAEFHGKEAIRIKNLKKEY
------------K-GQ------R-----------------------------EKVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLVLDIYEGQITALLGHSGAGKTTLLNLLSGLSVPTS--GSISIYNHTLSEMADF
ETVKD-LIGVCPQS--NIQFGFLTVRE-NLRLFAKVKGILPHEVE-QEVQQILRDLEMEN
IQDLLAQNLSGGQKR-KLTFGIAILGDPQV--LLLDEPTAGLDPLSKHHIWNLLKER---
---------------KSDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISHGR
LKCAGS--SLFLK---KRWGI---GYRL--SLHLN-E----------------------M
CDPESI-TSLVKQH--------------------IPDAKL----AAQSEEKLVYI--LPL
ER--TNKFPALYRDLDRCPNK---------GIENY--GVSMT----TLNEVFLKLEGK-S
TIDES---------DIAVW-GQL-QSDGT--------KDVACPVEPD----RDLSSLH--
----GARER-A-----------------------GGMALWKQQLCAIAKV---------R
FLKLKNE-RKSLLAMSLLFGVSFLPQVLELLLCRLYQK-SYSWGLSPDMYFLSLGQPP--
QDPLTHLLVI-----NK--TGS-SIENFIHSLRRQNIALEVDAFG----TRNG-TDDPSY
N-GAIIVSGDK-QDHR---FSVACNTKRLNCFP-VL-IDIISNGLLGIFN----------
----------STEH--IQTGRSTFLAEHMT-------Y-DYWYL-----SSAFIWILLAA
CFTPYIAMTSIDDTKEKI-HSQLWISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---MDYVFSPEEF-----IHIIQNLL-FQTLCSVGYVSSLVFLTYVIS
FIFRNGKKNSDIWSFFFLTV-----TIFTILATDI---SEYTF-LGLLFCTILIPPF---
--TLI--------GSLTIFSEIS----------YDF------VDYVGASESQIVFLALLI
PYFQFFIFVLVLRCLE-GNFRKKLLRKDPVF-RMTPRSSDVFPNPEEPEG----EDEDVR
MERIRAINAVT-ALDEE--EKPVITASCLRKEYAGKKKNCFSRRK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVK
KGEVVGLLGHNGAGKSTMIKMITGDIKPNAGQVI-LK--RSSE-------ED----TLGF
LGYCPQENVLWPSLTVKQHLEVYAAVKGLKKRDAT-----VTITG----LVEAFMLQDHL
KTPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQIWQAIRAT
FRHTERGALLTTHYMAEAEAVCDRVAIMVSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLEMKVKTLTQVEPL
HEEILRLFPCAA--RQERYSSL--MVYKLPIEDVQPLSQTFSKLETVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELDDFK-EELDP-SMMWKLLPQEEP----------------------
ENSPANP00000016541 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MRKREISVCQQTWALLCKNFLKKWR-----MKR
ESLMEWLNS
PF12698 // ENSGT00760000118965_1_Domain_0 (550, 1542)
-FLLLLCLY--IYP---HSHQVNDFSSLLTM--DLGRVDT--FNES-RFSV
AYTPVTN------TTQQIMNKVASAPFL----------------------------A--G
KE--VLGLPDEESIKEFTANY-----PEEIVRVIFTNTY-SY----HLKFLLGHEMPAK-
---KE----HKDHTA----------------HCYET---N-EDVYC-------EVSVF--
WKEGFVALQAAINAAIIEITTNHSVMEELMSVTGKNMKMHSF---------IGQSGVI--
TDLYLFSCIISFSPFIYYASVNV-----------TRERKRMKGLMTMMGLRDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AGFIFIMALFLAL----------VIKSTLFIILSGFMVVFGLFLLYG
LSLIALAFLMSI----------------------------LVKKSFLT---GLVV-----
FL-LTVFWGS--------LGFTALYRYLPASLEWILSLLSPFAFMLGMAQLLHLDYD---
------LNSNAFPHPLDGSNIIVATNFMLAFDTCLYLALAI
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRRSP
LFFLKSSFWSQTQKA-DHVA--LEDEMDADPS-SHDSFEPVPPEFHGKEAIRIRNVTKEY
-------------KGK------P-----------------------------DKIEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLVFDIYKGQITAILGHSGAGKSTLLNILSGLSTPTK--GSVTIYNNKLSEVADL
ENLSK-LTGVCPQS--NVQFDFLTVRE-NLRLFAKIKGILPQEAD-KEIQRVLLELEMKN
IQDVLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2449)
AGLDPFSRHQVWNLLKER---
---------------KTDRVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSQGK
LKCAGS--SLFLK---KKWGI---GYHL--SLQLN-E----------------------V
CVEENI-TSLVKQH--------------------IPDAKL----SAKSEGKLVYT--LPL
ER--TNKFPELYKDLDSYPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
TINES---------DIAIL-GEV-QVEKA--------DDTERLVEME----QVLSSLN--
----KMGKT-I-----------------------GGMALWRQQICAIARV---------R
LLKLKYE-RKALLALLLILMTGFCPLLVEYTMVNIYYS-SYTWELSPHLYFLAPGQQP--
HDPLTQLLII-----NK--TGA-SIDDFIHSVEHQNIALEVDAFG----TRNG-TDDPSY
N-GAITVCGSE-KNYS---FSLACNAKRLNCFP-VL-MDIVSNGLLGM
PF12698 // ENSGT00760000118965_1_Domain_4 (2449, 2719)
VK----------
----------PSVH--IQTERSTFLENGQ-----ANPI---GFL-----AYIMFWLVLTS
SCPPYIAMSSIDDYKNRA-RSQLRISG-LSPSAYWFGQ-ALVDVSLY-------------
---FLVFVFIYL---MSYISNVEDM-----LL-TIIHI-IQIPCAVGYSFSLIFMTYVIS
FIFHKGRKNSGIWSFCFYII-----TVFSVAGF-AF--IVFES-DIPFIFTFLIPPA---
--TMI--------GCLFL
ENSGT00760000118965_1_Linker_4_5 (2719, 2873)
SSHLL----------FS------SLLSEE-RMDVQPFLVFLI
PFLHFIIFLFILRCLE-WKFGKKSMRKDPFF-RISPRSSDVRQNPEEPEG----EDEDVQ
MERVRTANALN-STNFD--EKPVIIASCLRKEYVGKRKGCFSKRK--NKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVL-LK--GSS-------GGD----ALEF
LGYCPQENALWPNLTVRQHLEVYAAVKGLRKGDAD-----VAITR----LVDALKLQDQL
KSPVKTLSEGIK---RKLCFVLSILGNPSVVLLDEPSTG----MDPEG-QQQMWQAIRAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGKL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKNLAQVEPL
HAEILRLFPQAA--RQERYEIC--ELIHV-------------HPYAVKQSFDLE---EYS
L-SQSTLEQV----------------------------------------------FLEL
SKEQELGDFE-EDFDS-SVKWKLLPKEEP----------------------
ENSTSYP00000009592 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MCY----------------------------GRHGGRSS---GTSG-----
CC----VSGC--------SGC---------------------------------------
------------PDCCDAPAVATAELHVKSRLSTLGSAAPRERARDPLYK---DGHQHSP
SFCLKSSFWCKQP-NTHHEG--FENETHSEHS-SDDSFEPVSPEFRGKEAIRIRKVKKEY
-------------KGK------P-----------------------------GKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-Q--GISFDIYEGQITAILGHSGAGKSTLLNILSGLSASTE--GSVTICNTQLSEITDM
EEIRK-NIGFCPQF--NFQFDFLTVRE-NLRLFAKIRGIQPKEVE-QEVKRIIVELDMQS
IQDVIAKKLSGGQKR-KLTLGIAILGDPQI--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2509)
AGLDPLSTHQIWSLLKEC---
---------------KTDHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSNGN
LKCAGS--SLFLK---RKWGI---GYHL--SLHRN-E----------------------I
CDTEGI-TSLIKQH--------------------IPDAKL----TAESDEKLVYS--LPL
ER--TNKFPDLYGDLDKCSDQ---------GIMNY--GVSMT----TLNEVFLNLKGK-S
VTDEP---------DFSIG-KQE-KINVT--------RDTGNESEME----RALCSLP--
----EMSKA-V-----------------------SNGNLWRRQVCAVASL---------R
FLKLRRE-RKALLSLLLVLGVAFIPVILEKIIYKVFHE-IHCWELSPSMYFLSREQIV--
KPPLTSLLII-----NN--TGS-SIEDLIHSLKDQDIVLEIDDFR----NRNG-SDDPSY
N-GAIIVSGDQ-KDYR---FSVACNTKKMNCFP-VL-MGIVSNALLRMFN----------
----------FTKL--IQTERSIFSRDNV-------------MLDIGF
PF12698 // ENSGT00760000118965_1_Domain_4 (2509, 2719)
VDGRIFLLLIAN
CISPYIGMSSISDYKKKA-QFQLWISG-LCPSAYWCGQ-ALVDVPFY-------------
---GLILLSIYL---IHLFILL----RF---KLPWDLTFAAVVGIVGCAASLMLFTYGLS
FVFRKRKASDGLLAFGLFIM-----SVFMLIIL-LS--IHHGK-LSLIL-MILIPSY---
--TLI--------EFIMLLTELY----------LVHMKNSESLDNGINEVNKIVLLTALI
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
ENSLAFP00000000064 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MSKRHISASQQTWALLCKNFLKKWR-----MKR
ETLLEWFFS-FLLVLFAY-LSSS---HLHQVNDFPQMSAM--DLGRVDT--FNDS-DYVV
AFAPESK------TTQEIMNKVASAPFL------------------------------KG
RT--IMGFTDEESMNELELNY-----SIDAVRIIFNDTF-SY----HLKFSWGQRIPRM-
---EE----HRDHSA----------------HCRAV---D-EKITC-------DSSKF--
WEKGFIAFQAAINAAIIEITTNHSVMEELMSVTGIHMKILPF---------VAQGGIL--
TDFFIFFCIISFSAFIYYASVNV-----------CQERQSIKAVMTTMGLRESA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLIY-AGFIFIIATLMAL----------IVKSAQIVVLTSFMVVFILFLLYG
LSLITLAFLMSV----------------------------LIKKPSFT---GLVM-----
FL-LTVFWGT--------LGFTALYRHLPAFLEWTLCVLSPFAFTVGMAQLIHLDYD---
------VNSNAPLDPSSNPYLIVATFFMLLFDVLLYMALTLYFDKILPNE---YGHRHSP
LFFLKSSFWFQHQRA-NHMA--LENEIDFDPS-SNNSFEPVSPEFHGKEAIRIKNLTKAY
------------K-GK------H-----------------------------EKVDALKV
-MP--GLTFDVYE
PF00005 // ENSGT00760000118965_1_Domain_3 (1694, 1979)
GQITAFLGHSGAGKTTLLNVLSGLSVPTS--GSVTIYNRTLSEMADL
ESVIK-LTGVCPQS--NVHFGILTVKE-NLRLFAKIRGIQPQEVD-REVRRVLLDLEMEN
TQDILAQNLSGRQKR-KLTFGIAILGDPQI--LLLDEPTAGLDPLSRHRIWNLLKER---
---------------KSDHVILFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFISNGS
LKCAGS--SLFLK---KKWGI---GYHL--SLHLN-E----------------------M
CDPEGI-TSLIKHH--------------------IPDAKL----TAQSEEKLVYV--LPL
ER--TNKFPDLYRDLDRCSNQ---------GIENY--GVSMT----TLNEVFLKLEGK-S
AIEES---------DIGIW-RQV-QSDGA--------KDMGSLVGLE----QALSSLS--
----ESRKE-I-----------------------NGMSLWRQQVCAIAKV---------R
FLKLKNE-RKSLLTMLLLFGISFFPQLLEHLFYELYQK-SYSWGLSPDMYFLSPGQPP--
QDHLTDLLVI-----NK--TGS-SINNFIHSLRRQNIALEVDAFG----TRNG-TDDPSY
N-GAIIVSGDE-RDHR---FTITCNTKRLNCFP-VL-MDILSNGLLGIFN----------
----------SSKR--IQTDRSTYFEVHVN-------Y-EFGFL-----SNAFFWIPVAT
CFTPYIAMSSISDYRKKI-HSQLRISG-LYPSAYWFGQ-ALVDIPLY-------------
---FLILLLMQI---LDYVFSPDEI-----IFIIQNLL-IQILCSIGYVSSLIFLTYVIS
FIFRDGRKNRGIWSFCFIII-----TVFTIVATDL---NDYGF-LGLLLCTLLVPPF---
--TLI--------GSLFIYFEIS----------HDS------MDYLGPSESQIAFLALLI
PYLHFLIFLFVLRCLE-MNFRKNSMRKDPVF-RISPRSSEIFPNPEKPEG----EDEDVQ
MERVRTASAVT-APDFD--EKPVIIASCLRKEYVGKKKNCCMKKK--KKLAARNVSFCVG
K
PF00005 // ENSGT00760000118965_1_Domain_5 (2882, 3091)
GEIIGLLGHNGAGKSTTIKMITGDTKPTAGQVI-LK--GSRG-------ED----TIGF
LGYCPQENALWPNLTVREHLEVYAAVKGLRKGDAM-----TAITR----LVDALKLQDQL
KVPVKTLSEGMK---RKLCFVLSILGSPAVVLLDEPSTG----MDPEG-QQQMWQAIRAT
IRNTKRGALLTTHYMAEAEAVCDRVAIMLSGRLR--------------------------
----------------------------CIGSIQHLKSK-FGKDYLLELKVKPPAQVEPL
HAEILRLFPQAA--RQERYSSL--MVYKLPVEDVQPLSQAFFKLETVKQRFNLE---EYS
L-SQSTLEQI----------------------------------------------FLEL
SKEQELDGFD-EELDP-SVKWKLLPQEEP----------------------
ENSCLAP00000005683 (view gene)
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MVKRKISVCQQTWALFCKNLLKKWR-----MKR
DTLME
PF12698 // ENSGT00760000118965_1_Domain_0 (546, 1542)
WLYS-ALLLVTLY--TFS---TLHNVYDFSSMPSV--ELGRIDS--FNDS-RFVI
AYTPFNE------TTERIMNKVSSASFM----------------------------M--G
RK--AIAFPDEENMTELISTH-----YEDVVRVIFTSPL-SY----HLKFLRGFRIPSM-
---QE----HQDHSA----------------HCYEF---G-DGFDC-------GISQF--
WTKGFVTLQAAINAAIIEITTNQSVMEELMSVTGKHMKIDPF---------VHQEGLI--
TDFFIFTCIICFSPFTYYVSLNV-----------TRERKRMKGLMSMMGLCDSA------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FWLSWGLLY-AAFVFILALSLAF----------ITKSVQFVILTGFTVVFGLFFFYG
LSLITLAFLMSV----------------------------LLKKPFLT---GFVV-----
FL-VTVIWGS--------LGFMALYRYLPASLEWILSLFSPFAFTLGMAQLLHLDFD---
------MNSNA--DAVGDSNLIIVTIFMLFLDSFFYLTLTF
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YFEKILPNE---YGHRHSP
LFFLNSSFWHQQKPA-DHTA--LESETEPE-F-SDEAFEPVSTEFQGKKAIRIRNLTKEY
-------------KGK------P-----------------------------KSVEAL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--DLAFDIYEGQITTVLGHSGAGKSTLLNILTGLCVPTK--GWVTMYNNKLSEMPDL
ENISK-LTGVCPQS--NVQFDFLTVKE-NLRLFAKIKGIQLHKVD-NEVQRVLQELEMKN
IQNTLAQNLSGGQKR-KLTFGIAILGDPQI--FLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2483)
AGLDPFSRHRVWNFLKER---
---------------KADRVIVFSTQFMDEAD----------------------------
--------------------I---------------------------LADRKVFLSKGK
LKCVGS--SLFLK---KKWGI---GYHL--SLQLS-E----------------------T
CVHERI-TSLVKQH--------------------IPDAKL----SAESEGKLMYT--LPL
ER--TNKFPDLCRDLESCPDL---------GIENY--GVSMT----TLNEVFLKLEGK-S
DIDQP---------DIGTL-EDV-QAEGT--------RDTGRLLELE----EIVSWPD--
----GMSKA-K-----------------------AGMALLGQQVRAVARV---------R
FLKIKRE-RKVLFTLILIFGVGLLHILAANARKIFHQD-DYCWELSPQMYFLTPDQQP--
QDPLSNLLII-----NK--TGA-SIDDFIHSLEKQNIALEVDAFG----TRNG-TEDPSY
N-GAITVSGDR-KSYG---FSLACNTKRLNCFP-VL-VDIVSNGLLGMFT----------
----------PSVS--IQTDRS
PF12698 // ENSGT00760000118965_1_Domain_4 (2483, 2695)
TYPGVDD---IR-YQF---YNL-----AYLISWIILMS
SLSPYLSMTSIDDYKNKA-QFQLWISG-LNPSAYWFGQ-ALVEVPIY-------------
---LLFILFMYL---VFYASKLQGD-----IYTTVDIF-IQILYIVGYSISMIFMTYVIS
FIFRNGKKNSGIWSFCFYFV-----TLVSTVFM-V---DFFME-TSQFWTSILI
ENSGT00760000118965_1_Linker_4_5 (2695, 2873)
PPA---
--TLV--------GCTLLHFDHC----------LNA---YYGII-SAEQEKKHDFLAFLV
SYVHIIIFLVILRCLE-WKLGNKTMRKDPVF-RISPRRSSVSHNPEDPER----EDEDVQ
LERVRTANALT-SPNFE--QTPAIIASCLRKEYTENK-CLFFKKK--KKIAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNVSFCVR
KGEVLGLLGHNGAGKSTAIRMITGEAKPSAGQVL-LS--GSSE-------AK----PLGF
LGYCPQENVLWPSLTVREHLEVFAAVKGLSKADAP-----GAITR----LVEALKLHDQL
QAPVKTLSEGIK---RKLCFVLSILGGPSVVLLDEPSTG----MDPEG-QQQIWKAIQAT
FRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL---------------------------
---------------------------RCIGSIQHLKSK-FGKDYLLEMKVKTPAHVEPL
HAEILRLFPRAA--RQERYSSL--MVYKLPVEDVQPLSQAFFKLETVKHSFDVE---EYS
L-SQSTLEQVGQFLLFYFVQEIYMDSLICGCFALTWSYRRQCDIYISSFLLPPFQVFLEL
SKEQELGDFD-EELDP-SLRWKLLPQEEA----------------------
ENSODEP00000012627 (view gene)
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-----------------------------KKQRSVCQQTLALLRKNFLKKWR-----MKR
ESSLKL
PF12698 // ENSGT00760000118965_1_Domain_0 (547, 1542)
GLP-ILLGLYTC--LLS---YFGESMQFPGMPPQ--DLGRVDK--FNHS-IK-V
LYMPISN------TTQQIMNKTTFLPIM------------------------------RE
-N--VIGVPNKTYMDKMLMQE-----MPYAVGVIFSDTF-SY----KLKFFQGYTVPPL-
---KE-----TDLSP----------------HCWKG---YD-AFSC-------KLAMY--
WNRGFVTLQTVINAAIIEVTTNHSVMEELMSVTAINMKTLPF---------ISRYHFQ--
SEIFILFCLIYFSSCIYFVSLDI-----------TKERKMYKNLMKMMGLRDSA------
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---FWLSWGLIY-AGFIFIISLLITI----------IITATQAIVMTGFMVIFTLFFLYG
LSLVT--FLMSV----------------------------LLQKAVLA---NLIV-----
FL-LTLFWGC--------MGFTSFHRQLPSSLEWILSICSPFAFTSGMTQIIYEDYN---
------MNGVTFPDSSGDSYTMLATFAMLALDGLIYLLLAL
ENSGT00760000118965_1_Linker_0_3 (1542, 1682)
YSDRILPYG---YERRYSP
LFCLNSSSCFQHR-KTDNKV--FEKEVEPERH-FDDYFEAIAPEFQGKDAIRIRNVKKEY
-------------KGK------S-----------------------------EKVEVL--
-
PF00005 // ENSGT00760000118965_1_Domain_3 (1682, 1840)
-K--GLYFDIYESQITAILGHSGAGKSSLLNIINGLSVPTE--GSVTVCNKNISEIQDL
EEIRK-MIGFCPQH--NVQFDILTVKE-NLSLFANIKGILPQEVD-QKVQQILLELDMQN
IQNNLATDLNEGQKR-KLTFGIAVLGNPRV--LLLDEPT
ENSGT00760000118965_1_Linker_3_4 (1840, 2303)
AGLDPFSRHRVWSFLKEC---
---------------RANHLILLTTQSVDEAD----------------------------
--------------------I---------------------------LADRTMILSNGR
LKCAGS--SAFLK---RKWGL---GYHL--SFYKN-E----------------------I
CDPEQV-TAFINHH--------------------IPDAKL----KTENKEKLVYA--LPS
ER--TSEFPDLFRDLERCSGQ---------GLMSY--DISMP----TLSEVFMNMEGT-S
TVDQD----------------GE-HNGMM--------GDSESLGEIE----PAYSSRP--
----EVQKP-V-----------------------GKAELWWMQACAMARL---------R
FLKLIRG-RKSLLVLLLIFGLA
PF12698 // ENSGT00760000118965_1_Domain_4 (2303, 2717)
SFPLIMEDIFYYMLAQ-NVDWEFKTELYFLSPGQLS--
QDPRTSLLII-----NH--TES-DIEDFIQSLKHQNILLEVDDFK----NRNG-TEALSY
N-GAIIVSGKR-KDYR---FSVVCNTKRIHCFP-IL-MSIISNGLLWMFN----------
----------QTQY--IRTERSPFPQS-Y-------------LPWMGMPDGVVVMFYAAC
SFSPYMAMSSIGDYKKKA-KSQLWISG-LFPSAYWIGQ-AVVDIGLF-------------
---SLSLLLMYL---IVCFTRM---RDS---VITSRIIFTLVVSSFGYAVSMIFFTYVIA
FIFRKRTKNSGLCQL---IS-----VSISF------------------------------
---------------S
ENSGT00760000118965_1_Linker_4_5 (2717, 2873)
FWCFQRI----------YSQQREHEE---GNFDLSGVDLLVCLI
PYLQAFLFIFVLRCME-LKFGKKVIQKDPLF-RIAPPNPDTQPNPEEP--GD--EDEDVQ
AERMRTSIALT-TSNLE--EKPVIIASCLHKEYTGQKKNCFSKRK--KKLAT
PF00005 // ENSGT00760000118965_1_Domain_5 (2873, 3037)
RNISFSIK
KGEIFGLLGPNGAGKSSSIRMIAGITKPTAGKVE-LK--GHHSV-WDDQGAD---V-VRF
LGHCPQENVLWPRLTVKEHLEVYAVVKGLRKADAA-----IVISR----LVNTFKLHEHL
NVPVGQLAAGTT---RKLCFVLSILGDSPVLLLDEPSTG----VDPSG-QHQIWQAVQMS
VKNTDRAILLITHYLAEAEALCDRVAIMVSGRL---------------------------
---------------------------RCIGSIEHLKRK-FGKDYILQLKVKESSQVPLV
HAEILKLFPQAA--EQERCASL--LTYKLPLGDVYPLSQAFHKLEEVKHTFHLE---DYC
L-SQCTLEKV----------------------------------------------FLEL
SKEQELGNVD-EEIDT-TMRWKLLPHSDEP---------------------
{"ENSMMUP00000024472": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2304], ["Domain_4", 2304, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSHGLP00100021572": [["Domain_0", 543, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Domain_5", 2873, 3037, "PF00005"]], "ENSDORP00000009024": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2502], ["Domain_4", 2502, 2768, "PF12698"], ["Linker_4_5", 2768, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSAPLP00000006668": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSMLEP00000014978": [["Domain_0", 843, 1542, "PF12698"]], "ENSPVAP00000001851": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSMAUP00000010113": [["Domain_0", 543, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Domain_5", 2873, 3037, "PF00005"]], "ENSCATP00000027890": [["Domain_0", 545, 1495, "PF12698"], ["Linker_0_3", 1495, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2302], ["Domain_4", 2302, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSGALP00000006898": [["Domain_0", 548, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2300], ["Domain_4", 2300, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSRBIP00000008086": [["Domain_0", 545, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2304], ["Domain_4", 2304, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSMICP00000023143": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2399], ["Domain_4", 2399, 2770, "PF12698"], ["Linker_4_5", 2770, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSRROP00000044231": [["Domain_0", 551, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2471], ["Domain_4", 2471, 2719, "PF12698"], ["Linker_4_5", 2719, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSCSAP00000000698": [["Domain_3", 1708, 1840, "PF00005"], ["Domain_5", 2896, 3037, "PF00005"]], "ENSPPAP00000007959": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2397], ["Domain_4", 2397, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSPVAP00000001852": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSMLUP00000017519": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3054, "PF00005"]], "ENSHGLP00000002330": [["Domain_0", 543, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Domain_5", 2873, 3037, "PF00005"]], "ENSCANP00000000376": [["Domain_0", 545, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2303], ["Domain_4", 2303, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSTBEP00000006006": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSSARP00000010186": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2991, 3091, "PF00005"]], "ENSMUSP00000036338": [["Domain_0", 542, 1542, "PF12698"], ["Linker_0_3", 1542, 1685], ["Domain_3", 1685, 1840, "PF00005"], ["Linker_3_4", 1840, 2448], ["Domain_4", 2448, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSRBIP00000026566": [["Domain_0", 844, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2486], ["Domain_4", 2486, 2723, "PF01061"], ["Linker_4_5", 2723, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSAMEP00000011084": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSCAPP00000017609": [["Domain_0", 555, 1386, "PF12698"], ["Linker_0_3", 1386, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2513], ["Domain_4", 2513, 2718, "PF12698"]], "ENSP00000467271": [["Domain_0", 551, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2381], ["Domain_4", 2381, 2718, "PF12698"], ["Linker_4_5", 2718, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSP00000342216": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2398], ["Domain_4", 2398, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSMMUP00000048627": [["Domain_0", 550, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2434], ["Domain_4", 2434, 2768, "PF12698"], ["Linker_4_5", 2768, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSHGLP00000001515": [["Domain_0", 550, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Domain_5", 2873, 3037, "PF00005"]], "ENSRBIP00000012069": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2396], ["Domain_4", 2396, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSMODP00000007666": [["Domain_2", 1675, 1728, "PF03193"], ["Domain_3", 1708, 1840, "PF00005"], ["Domain_5", 2896, 3037, "PF00005"]], "ENSOGAP00000001088": [["Domain_2", 1674, 1718, "PF03193"], ["Domain_3", 1708, 1840, "PF00005"], ["Domain_5", 2896, 3037, "PF00005"]], "ENSPVAP00000001854": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSCGRP00000018732": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2301], ["Domain_4", 2301, 2759, "PF12698"], ["Linker_4_5", 2759, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSFDAP00000021349": [["Domain_0", 543, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2298], ["Domain_4", 2298, 2723, "PF12698"], ["Linker_4_5", 2723, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSMFAP00000034471": [["Domain_0", 545, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2304], ["Domain_4", 2304, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSPTRP00000069214": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2397], ["Domain_4", 2397, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSPTRP00000044984": [["Domain_0", 551, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2398], ["Domain_4", 2398, 2714, "PF12698"], ["Linker_4_5", 2714, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSETEP00000005005": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSMNEP00000021978": [["Domain_0", 784, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2415], ["Domain_4", 2415, 2770, "PF12698"], ["Linker_4_5", 2770, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSRROP00000034365": [["Domain_0", 783, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Domain_5", 2881, 3037, "PF00005"]], "ENSPPAP00000034448": [["Domain_0", 551, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2398], ["Domain_4", 2398, 2714, "PF12698"], ["Linker_4_5", 2714, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSETEP00000001263": [["Domain_3", 1694, 1852, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSMFAP00000033729": [["Domain_0", 786, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2513], ["Domain_4", 2513, 2770, "PF12698"], ["Linker_4_5", 2770, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSCGRP00001027759": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1685], ["Domain_3", 1685, 1840, "PF00005"], ["Linker_3_4", 1840, 2440], ["Domain_4", 2440, 2719, "PF12698"], ["Linker_4_5", 2719, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSMMUP00000045716": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2392], ["Domain_4", 2392, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSVPAP00000003190": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSNGAP00000008993": [["Domain_1", 1326, 1541, "PF12698"], ["Linker_1_3", 1541, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2366], ["Domain_4", 2366, 2770, "PF12698"], ["Linker_4_5", 2770, 2873], ["Domain_5", 2873, 3033, "PF00005"]], "ENSCGRP00000022735": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1685], ["Domain_3", 1685, 1840, "PF00005"], ["Linker_3_4", 1840, 2434], ["Domain_4", 2434, 2719, "PF12698"], ["Linker_4_5", 2719, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSETEP00000000297": [["Domain_3", 1694, 1979, "PF00005"]], "ENSCGRP00001027182": [["Domain_0", 587, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2503], ["Domain_4", 2503, 2703, "PF12698"], ["Linker_4_5", 2703, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSFCAP00000014537": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Domain_5", 2873, 3037, "PF00005"]], "ENSTSYP00000028696": [["Domain_0", 552, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2400], ["Domain_4", 2400, 2770, "PF12698"], ["Linker_4_5", 2770, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSPSIP00000010295": [["Domain_3", 1708, 1840, "PF00005"]], "ENSAMEP00000007641": [["Domain_3", 1694, 1979, "PF00005"]], "ENSTSYP00000000828": [["Domain_0", 545, 1542, "PF12698"], ["Linker_0_3", 1542, 1686], ["Domain_3", 1686, 1839, "PF00005"], ["Linker_3_4", 1839, 2301], ["Domain_4", 2301, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSPPYP00000009632": [["Domain_5", 2989, 3037, "PF00005"]], "ENSODEP00000014210": [["Domain_0", 552, 1542, "PF12698"], ["Linker_0_3", 1542, 1685], ["Domain_3", 1685, 1840, "PF00005"], ["Linker_3_4", 1840, 2503], ["Domain_4", 2503, 2771, "PF12698"], ["Linker_4_5", 2771, 2882], ["Domain_5", 2882, 3037, "PF00005"]], "ENSNGAP00000008691": [["Domain_0", 543, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Domain_5", 2873, 3037, "PF00005"]], "ENSCHOP00000009419": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSSHAP00000003072": [["Domain_5", 2896, 3037, "PF00005"]], "ENSMLUP00000007589": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSCATP00000009541": [["Domain_0", 786, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2514], ["Domain_4", 2514, 2770, "PF12698"], ["Linker_4_5", 2770, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSAMEP00000011173": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSMICP00000038172": [["Domain_0", 542, 1542, "PF12698"], ["Linker_0_3", 1542, 1685], ["Domain_3", 1685, 1840, "PF00005"], ["Linker_3_4", 1840, 2421], ["Domain_4", 2421, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSOGAP00000001092": [["Domain_3", 1708, 1840, "PF00005"]], "ENSBTAP00000009089": [["Domain_3", 1708, 1840, "PF00005"], 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["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2397], ["Domain_4", 2397, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSPTRP00000016277": [["Domain_0", 545, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1839, "PF00005"], ["Linker_3_4", 1839, 2303], ["Domain_4", 2303, 2704, "PF12698"], ["Linker_4_5", 2704, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSCSAP00000000683": [["Domain_3", 1708, 1840, "PF00005"], ["Domain_5", 2896, 3037, "PF00005"]], "ENSEEUP00000002191": [["Domain_3", 1694, 1979, "PF00005"], ["Domain_5", 2882, 3091, "PF00005"]], "ENSGGOP00000015726": [["Domain_0", 544, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], ["Linker_3_4", 1840, 2397], ["Domain_4", 2397, 2771, "PF12698"], ["Linker_4_5", 2771, 2873], ["Domain_5", 2873, 3037, "PF00005"]], "ENSHGLP00000002103": [["Domain_0", 546, 1542, "PF12698"], ["Linker_0_3", 1542, 1682], ["Domain_3", 1682, 1840, "PF00005"], 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