ENSGT00760000118924_4 : Linker Region Query Results

------------------------------------------------------------
------------------------------------------MSDFK-DV----------
DAQLGSLDE----------------EE-LIASGAKHSFQRFGFRP--------PGGLRS-
I---AGFLGRGHI-PLVLKL-----------------LCLMLLAGI--LMA--VLFKVSK
------VSH-----------------------------------------FYE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QKRSK-----QE
DI--HQELTQAEAEM---------------------------------------------
---DRLC--RPCPWD-----WTFFQG-HCYFFSKS-QRNWNDSVTACQEVGAQLVIIKSA
EE-----------------------------------------------QNFLQL--TSK
NKGSTWMGLS--D--LNKEGTWLWVD-GSPLF------FRFMKF----WNEGEPNS----
H------GEEDCAEFRG--DGWNDSRCDL-EKF--WICKKSAGS-CSEGG----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VS-GGY--------
-WRRWEHWSRRPL-FLALAVL----------------VTIVLWAVI--LSI--LLSKA--
---------------------------------------YMECAALLGGQD---------
--LLRTN-ASKQTTVLSALKED----VGACHSCCSGT-QSKLL-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELHER-----------------------VTQGLAEAGRDRENVRT
EL--FRALEAVRFQN---------------------------------------------
----SSC--EPCPQS-----WLPFEG-SCYFFSVP-KTTWAAAQSHCADASAHLVIVGDL
DE-----------------------------------------------QGFLTRN-T-R
-GHGYWLGL-RAVRQLGKVQGYQWVD-GVSLT---------FSH----WNRGEPNDS---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------------------------MAEA--R---QSPN---
PNEITAL-R----------------TK----LPLQQGNTGKWGQT--S-QDKT--W----
------------K-YLCLFVS----------------LILLLVVII--SSV--VLSEVLK
R--------------T--------------------------------------------
------------------------------------------------------------
----------------------------------------KQMQKEVFQ-----------
----------------------LKE-------KVTQGL----------GDAGHDRDFIRG
EV--FRQMK------------------------------------------------AVL
AGNETSC--EPCPLG-----WKVFQG-SCYFFSLD-KLTWTQANDSCVQKQAHLVVINSR
TE-----------------------------------------------QDFLTTT-G--
-QVTSWIGLF--K--EGQKGNHKWMD-GSTPT---------YTN----WNSKEPHDN---
-----I-TAPACMLMQS-YGQWSDISCEL-GRF-AFICERRQNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------SHYAP--P---AGFSE-SP-RKRCC------
--------GWG-T-RLALLGL----------------ATAALWAGL--LSL--LLMWHWD
T--------------LRSQRLLEETTARN------VSHISKDLQRHQHDQM---------
--AQKSQ-AAQMLQDMEKLR----------------------------------------
----------------------------------AEQKRMKSQDAELSGNLD--------
---------------GLHEDLN------N-----LKAQ-----ALNERRAAADSLARLQE
EV--AKLRVELQLS----------------------------------------------
--KGAAC--DTCPDE-----WVHFQQ-KCYYFGEG-AKKWLHAQYACEDLGGRLASIHSA
EE-----------------------------------------------QDFLSKR-A--
NWKGSWIGLQ--D--LDREGQFTWMD-GSPMG---------YSN----WYPGEPNNQ---
-----G-QGEDCVMMRG-SGQWNDAACHS-KLD-SWVCDRLATC-GP-PATSTPEG---P
PGTTPSL----------------------------------------------

------------------------------------------------------------
---------------------------------------SPGPPHSAQSV---------V
P-----PSE----------------EK-ATFRGQRFTEKDPEMLT--------QR--PKN
F---PGWLTRVPW-IL-LLLL---------SSLCL---CFVLLVTT--LVQ------GES
GR-GLYLL-----------------------------------G---L--G--V--G---
-----------------LW--A--P-F---R---------C--E--Q---V--L---S--
-G-------L--E----Q-V-----------R----------------QQLTWINTSLGR
-------------------CR---------------------------GPGTP-----HS
------------SSP---------------------------------------------
---AALC--RPCPWG-----WEAFQG-NCYFFSRT-LGTWENSVSSCQDMGAHLVIINNG
AE-----------------------------------------------QRFLRYW-DIR
KSQRTWIGLS--D--HNNEGSWHWVD-NTPLQ------LSY-------WKEGEPNN----
A------GNEDCVELFV--EDWNDNKCTA-QNF--WICERPSAR-CPGA-----------
-----------------------------------------------------

------------------------------------------------------------
-----------------------------------------------MPR----------
A------------------------GRLLTMDTAGYSKWGGGLED-VP-GGS--------
-WGRWGRWGQRLL-FLGLVLA----------------VATVLWALI--LNI--LVSKA--
---------------------------------------STERRALLGHQD---------
--LLRTN-ASEQSAALGALNRE----VRACNTCCLGT-QKLLQ-------R-----ARTE
L-------------------------------------------GEAQAKLIQQESAL--
--------------KELSDR-----------------------VTQSLAEASRDREGIRT
EL--FRALEAVRQGN---------------------------------------------
----SSC--EECPES-----WLPFQG-SCYLFSVQ-RATWEASQQNCAGAGAHLVIVGDL
EE-----------------------------------------------QGFLSRN-T-R
-GRGFWLGL-RAVRRAGKIQGYQWID-GVPLS---------FSQ----WNTGEPNDS---
------MGREDCAMMLRTG-MWNDAPCEN-EKD-NWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MG-
C---LGFLDRGHI-SLVLQL-----------------LLLILFAGL--LAA--IIIQVSK
------IPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------MQLEETK-----QE
KM--YRDLSQLKSEV---------------------------------------------
---DSLC--RHCPWD-----WTFFNG-NCYFFSKS-KRNWHDSITACQEVGAQLVIVKSH
EE-----------------------------------------------QSFLQQ--TSK
KNGYTWMGLS--D--LNKEGAWYWLD-DSPLS------DRLGKY----WNRGQPNN----
I------GGQDCVEFRD--EGWNDAKCDE-MKL--WICKKSATT-CSSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------MTPQSRAEGRGPRPA-----------ME--QQEFTKFS---R-RRRPCC-----
--------CRG-T-QLALLAL----------------VTTALWAGL--LTL--LLLWHWE
S--------------ARNLKQLEETAAQN------VSQVSKDLERHKGDQM---------
--AQKSQ-AAQMMQNMERIQ----------------------------------------
----------------------------------TEQKRMESQESELSWNLDGLRADLSD
LKSR---------------------------------------GLNEMRQALDSLGRLQE
EV--GKLWIELRAS----------------------------------------------
--NGSVC--NTCPEA-----WIYFQK-KCYYFGEG-AKKWIQARYACEDLDGRLVSIHSP
EE-----------------------------------------------QDFLTKR-A--
NWRGSWIGLR--D--LDIEGEFIWMD-NQPLD---------YSN----WQPGEPNDG---
-----G-QGENCVMMLG-SGKWNDAFCGS-DLH-GWKRKSQTCS-CDSRAHLRK-R---R
D---PQWATQD-------------HAES-------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------RGLGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSISQEESRQDVIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--P---------------------------------------------------------
------------------------------------------------------------
--EKSKQQEIYQELTRLKAAVG------------------------ELPEKSK-----QQ
EI--YQELTQLKAA----------------------------------------------
--VERLC--RRCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACKEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNQEGTWQWVD-GSPLL------PSFNQY----WNRGEPNN----
V------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEEQFLSP---A
P----AT---------------------PN-PP-------PA-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------TQDLATAGRDRENIRN
EL--FRALEAAKLQN---------------------------------------------
----GSC--GQCPTS-----WLPFRG-SCYYFSEP-RTTWQEAERNCVGNAAHLVIIGDL
DE-----------------------------------------------QGFLTRH-T-R
-GRGYWLGL-RAVRSGGRVQGYQWVD-GVSIS---------FSH----WNVGEPNDS---
------QSKEDCVMMLHSG-LWNDAPCSS-ERD-GWICEKRSSC-AGH------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------------------------MESIQYN---RWET---
SEEFEMA-D----------------TK----RQWRPWEAGWWAKQ-LP-GGRP--A----
------------F-PLYLLFS----------------VTSFLWIIL--LSM--LLSKVME
--------------------------------------LSREIENLDEQLE---------
--RIQVN-GSKNSEKLVALQVD--------------------------LNS----SDS--
------------K-------------------HQTLKAKAETMAETLRN-----------
----------------------LQESQASLSTTLSQEL----------AEAREDRENIRS
EM--FRGLE------------------------------------------------AVR
SENGSFC--QPCPSP-----WKAFQG-SCYFFSKI-KLTWSKARDDCIQKKAHLVIINNR
DE-----------------------------------------------QNFLTPT-E--
-RLGFWIGLR--K--V-KEGIHKWID-GTSLG---------YTN----WNEGEPNDS---
-----Q-GRENCVMMLH-HGKWNDFTCEV-SSD-NWICEKRQTC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------M--------RIQQMG-
S---LGFLDRSNI-PLVLQL-----------------LFLILFAGL--LVA--IVIQVSK
------IPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------VQWEQTK-----QE
KM--YQDLSQLKSEI---------------------------------------------
---DSLC--RLCPWD-----WTFFNG-NCYFFSKS-QRDWHNSITACQEMEAQLVTIKSP
EE-----------------------------------------------QSFLQQ--TSK
KNGYTWMGLS--D--LNKEGEWYWLD-GSPLS------DSLRNY----WNEGQPNN----
I------DGQDCVEFRN--DGWNDAKCDN-WKF--WICKKTATT-CSSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDPKDTG----------
KKQLGPLDE----------------EQ-LISSHSRYSTKGFDFQP--------NSGFSS-
F---TGHLGLSHV-PLALQV-----------------LFLIVFSVL--LVV--VLA----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------K---------------------------------------------
---DRLC--RSCPWD-----WTPFQE-SCYFFSVA-QKTWNDSATACQKVGAQLVVIKSD
EE-----------------------------------------------QNFLQQ--SSK
KRGNTWMGLI--D--LNKESTWHWVD-GSPLT------LSFMKY----WNKGEPNN----
L------GEEDCAEFKG--DGWNDHQCDD-KKF--WICKKPKTS-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MQDP-------------------
EIAEAVCLDRKPF-ITVL-KL---------ISIVL-------------------------
------------------------------------------------------------
------------------L--A--A-L-----------------------I---------
---------I-------AVIV--------KGTEFLTSQDYDQQKENIHQKLDQVKAGLK-
------------------------------------------------------------
------------------------------------------------------------
----HLC--RPCPWLLFQGDQSLFQR-NCYFFSIS-KKNWMESVKACKYMGAQLVVIKSN
EE-----------------------------------------------QSFLQGI-SK-
KKGNFWMGLS--Y--NNKESKWQWVD-GSPLQG---RVFNFRTY----WSAGEPKM----
R------GNKDCAIRTD--YGWNALPCSH-ESL--WICMKPALP-CPNTW----------
-----------------------------------------------------

--------------------------------------------------MLHPQP--SP
AQNSDWSMNRFLL-----GVTAAKEMGGREERKKGRARVGLEFKCGSLPR----------
L------------------------DARGTMDTVRYSQWESSPEE-VPGGGP--------
-WGRWEYFRPRVC-LLALAVL----------------AVTVLWALI--LSI--LLSKA--
---------------------------------------STDRGALLDRQD---------
--LLRTN-ASEQTVVLGALKRE----VGACRSCCNAT-KATLL-------E-----AVAD
L-------------------------------------------RKAEATLLEQKSAL--
--------------EQLRQR-----------------------VTQDLATAGRDRENIRN
EL--FRELENARLQN---------------------------------------------
----SSC--EQCPTS-----WLPFRG-SCYYFSEP-QATWPEAERNCLGNDAHLVIIGDL
DE-----------------------------------------------QGFVTRH-T-R
-DRGYWLGL-RGVRSAGRIQSYQWVD-GVSLG---------FSH----WNLGEPNDS---
------RGQEDCVMLLHTG-LWNDAPCSS-ELD-GWICEKRRRC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RR-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------TQSLKQLEERAARN------VSQVSKNLESHHGDQM---------
--AQKSQ-STQISQELEELR----------------------------------------
----------------------------------AEQQRLKSQDLELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNEASDLLERLRE
EV--TKLRMELQVS----------------------------------------------
--SGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWVHARYACDDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTGSWIGLR--N--LDLKGEFIWVD-GSHVD---------YSN----WAPGEPTSR---
-----S-QGEDCVMMRG-SGRWNDAFCDR-KLG-AWVCDRLATC-TP-PASEGSAE---S
M--GPDSRPDP-------------DGRLPT-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQPLGLLEE----------------DP--TTSGIRLFPRDFQFQQ--------THGHKS-
S---TGCLGH--G-PLVLQL-----------------LSFTLLAGV--LVA--ILVQV-R
VPSSLSQEQSEQDVIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSK-LQEIYQELTWLKAA----VGELPEK------SQLQEIYQELTR-----LKAA
VGE-------LPEKS---------------------------------------------
----------------------------------------------------R-----LQ
EI--YQELTRLKAAVG--ELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLK
TAFERLC--CRCPKD-----WTFFQG-NCYFMSNS-QRNWHDSVTACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-TYR
SNRFSWMGLS--D--LNQEGTWQWVD-GSPLS------SSFQRY----WNSGEPNN----
S------GDEDCAEFSG--SGWNDNRCNI-DNY--WICKKPTA--CFRDE----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDASGYSKWSSAPDE-VS-SGP--------
-WGRWERWGWRPL-FVALALV----------------AGIVLWALV--LSI--LFSKA--
---------------------------------------STEHEALLHGQD---------
--LLRTN-ASNQSAVLDTLTME----VGSCRKCCLET-QGMLK-------T-----ARVD
L-------------------------------------------GEAQKKLLEQESTL--
--------------KELSER-----------------------VTQDLAKAGEDRENIRT
EL--LRALEAAKLGN---------------------------------------------
----SSC--EACPAS-----WLPFEG-SCYLFSTV-RAPWDEAQKNCAGAGAHLVIVGGL
EE-----------------------------------------------QTFLSRN-T-R
-GRGFWLGL-RAVRLGSKIQRYQWVD-GAPIS---------FSH----WNQGEPNDS---
------RGQEDCVMMLRTG-LWNDAPCTS-LND-NWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------WD
T--------------LENLKQLEKAAARN------VSQVAKDLQRHQSDQM---------
--AQKSQ-XXXXXXXXXXXX----------------------------------------
----------------------------------XXXXXXXXXXXXXXXXXXXXX-----
---------------XX-XXXX------X--------------XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX----------------------------------------------
--XXSMC--NLCPKD-----WVNFKH-KCYYFGKG-AKKWIQARYACEDLGGRLVSIHSR
EE-----------------------------------------------QDFLTTR-A--
NKKGSWIGLR--D--VFVEGEFLWMD-GSPVY----------------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAEMCDSK---------D
L-----GDP----------------EE-EMFGDRRVTKKYTGLLR--------G---SKI
L---PGCLTRAQL-PL-LLLL---------VSVGF----FLLLVAT--LVQ------VSS
VR-QSLQKEKWDH-------------------Q--------Q-S---P--S--Q--V---
------------------------G-V---S---------Q--K--P---P--R---S--
-D-------L--D----E-I-----------L----------------QQLTWMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RPCPWK-----WELFQG-TCYFFSQT-QNVWKDAISACQNLRAQLVIINST
AE----------------------------------------------------------
--QRTWIGLS--D--HHNEGSWKWLD-DSPVQ------LSF-------WKEGEPNN----
H------GDEDCVELYS--EGWNDNRCSV-ENF--WTCEKPSSP-CPGS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKVAVSELS-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-QQEI---------------------------------YQELTW-----LKAA
VGE-------LPEKSKLQEIYQEL----TRLKAAVGELPEKSKQQEIYQELTRLKAAVGE
LPEKSKQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHNSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LHHEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSGDEERLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
-----MA-D----------------SK----LQWRPWEAGWWAKQ-LP-GGRP--A----
------------L-PLYLLFS----------------VTSFLWILL--LSM--LLAKVMD
--------------------------------------LSRDMEHLNEQLE---------
--GIQVN-ESTKAGKLAALQIS--------------------------LST----SDN--
------------K-------------------HQTLKIKVEAMAEELRK-----------
----------------------LQEKQTSLSTNLSQDL----------SEAKKDRDDIRS
EM--FRGLE------------------------------------------------AVR
NGNGSSC--QPCPSP-----WRDFQG-SCYFFSEN-KLPWSKARDDCVQKQAHLVIINNH
DE-----------------------------------------------QNFLNPT-E--
-FLGYWIGLR--K--T-KGGVHKWID-GSGLS---------YTN----WNPGEPNDS---
-----K-GEEDCVMMLH-HGRWNDFTCDK-SSD-NWICEKRQIC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAEMCDPK---------E
P-----DDP----------------EV-EVFGDQRLAKKYTGLLR--------S---SRS
L---PGCLTQAHL-PL-LLLL---------VSLGF----FMLLVTT--LVQ------VSR
IH-QSLQRDTGDH-------------------R--------E-R---N--H--Q--ES--
P----------------GL--G--D-V---S---------Q--A--Q---K--Q---S--
-S-------L--E----E-I-----------L----------------QQLTWMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RHCPWK-----WELFQG-SCYFFSLT-QNTWKESIAACQNMRAQLVVINST
EE-----------------------------------------------QKFLKSW-NTK
NSQRTWIGLS--D--HHNEGSWRWVD-NTPLQ------LSF-------WKEGEPNN----
H------GDEDCVELYS--DGWNDNRCST-ENF--WICLQGTPN----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------M--------RAPQMG-
S---LGFLDKGHI-PLVLQL-----------------LFLILFTGL--LVA--IIIQVSK
------MPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------IQWEHTK-----QE
KM--YKDLSQLKSEV---------------------------------------------
---DRLC--RLCPWD-----WTFFNG-NCYFFSKS-QRDWHDSITACKEMEAQLVIIKSH
EE-----------------------------------------------QSFLQQ--TSK
KNGYTWMGLS--D--LNKEGEWYWLD-GSPLS------DSFKKY----WKKGQPNN----
I------GGQDCVEFRD--NGWNDAKCEK-RKF--WICKKIATT-CLSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEMG----------
KRQLGPLDE----------------EL-LTSSHTRHSIKGFGFQP--------NSGFSS-
F---TGCLVHSQV-PLALQV-----------------LFLAVCSVL--LVV--ILVKVYK
------IPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S------------------------Q--EENN-----QM
NV--YQELTQLKAGV---------------------------------------------
---DQLC--RSCPWD-----WTHFQG-SCYFFSVA-QKSWNDSATACHNVGAQLVVIKSD
EE-----------------------------------------------QNFLQQ--TSK
KRGYTWMGLI--D--MSKESTWYWVD-GSPLT------LSFMKY----WNKGEPNN----
L------GEEDCAEFRD--DGWNDTKCTN-KKF--WICKKLSTS-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEENE--Y---SGYWE-PP-RKRCCC-----
-------ARRG-T-QLMLVGL----------------LSTAMWAGL--LAL--LLLWHWE
T--------------EKNLKQLGDTAIQN------VSHVTKDLQKFQSNQL---------
--AQKSQ-AVQMSQNLQELQ----------------------------------------
----------------------------------AEQKQMKAQDSRLSQNLTELQEDLRN
ARSQ--NSELSQNLNRLQDDLV------N-----IKSL-----GLNEKRTASDSLEKLQE
EV--AKLWIEILIS----------------------------------------------
--KGTAC--NICPKN-----WLHFQQ-KCYYFGKG-SKQWIQARFACSDLQGRLVSIHSQ
KE-----------------------------------------------QDFLMQH-I--
NKKDSWIGLQ--D--LNMEGEFVWSD-GSPVG---------YSN----WNPGEPNNG---
-----G-QGEDCVMMRG-SGQWNDAFCRS-YLD-AWVCEQLATC-EI-STPLASVT---P
TRPTPKSEP--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------PSARLWGGS--------
---------------A----------------------------YSPSPRNNSSLSTLPT
SVPTTVVPLSLSST----------------------------------------------
--PGSMC--STCPEN-----WVNFQR-KCYYFGEG-AKTWIQAKYTCSDLQGRLVSIHSAEE-----------------------------------------------QDFLTKH-S--SWKGSWIGLR--D--LDIEGEFIWMD-GSPVD---------YSN----WRPGEPNNG--------G-LGEDCVIMLG-SGQWNDGFCRS-EQS-GWVCDRLATC----------------------------------------------AKTWIQAKYTCSDLQGRLVSIHSA
EE-----------------------------------------------QDFLTKH-S--
SWKGSWIGLR--D--LDIEGEFIWMD-GSPVD---------YSN----WRPGEPNNG---
-----G-LGEDCVIMLG-SGQWNDGFCRS-EQS-GWVCDRLATC----------------
-----------------------------------------------------

-----------------------------------------------------VTPKNQD
--CSSWT--------SWVRLGWDAGILGRE-------K-GWPALASACPG---------S
EFTSIHSEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKVAVSELS-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-QQEIY---------------------------------EELTR-----LKAA
VGE-------LPEKSKLQEIYQEL----TRLKAAVGELPEKSKQQEIYQELSRLKAAVGD
LPEKSKQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFISNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFAWMGLS--D--LNQEDTWQWVD-DSPLS------TSFKQY----WNRGEPNN----
I------GEEDCVEFNG--NGWNDDKCSA-AKF--WICKKSAAS-CSRDEGQLLSS---A
S----AS---------------------PI-AH-------AA-----------

------------------------------------------------------------
------------------------------------------TRNSKEAR----------
TQQLGPLGD----------------EG-LVPGGPRHSLKSFGYRL---------PEFKC-
F---AGCQDKGLI-SLVLQL-----------------LALILFAGL--LVA--ILAQVSK
------VPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------RKKEKSN-----QE
KM--YQELNQLKTGF---------------------------------------------
---DCLC--RPCPWD-----WTFFQR-KCYFFSRS-QRDWRDSITTCQEVGAQLVIVENA
EE-----------------------------------------------QSFLQQ--TSK
SKGYAWMGLS--D--LNKESEWHWVD-GSPLS------LSLVRY----WNKGQPNN----
Y------EEQDCVEFD---DGWNDAKCDL-QKF--WICKKPGTS-CSTE-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------DTEVQLGS--------------LP-
T---QGCRDNDLV-SLALQL-----------------LSLVLFAGL--LVA--ILAQVSK
------VPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------D------------------------QEKEKSN-----QE
KI--YQELTQMKTEF---------------------------------------------
---DRLC--RPCPWD-----WISFQG-KCYFFSKS-QQGWHEAITACKEVGAQLVIVEND
EE-----------------------------------------------QSFLQQ--TSK
SKGYAWMGLS--D--LNQESAWRWVD-GSPLA------LSLMQY----WNKGQPNN----
Y------EEQDCVEFRG--DGWNDAKCDL-KKF--WICKKPATP-CSK------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTESR----------
MQQLSSVDD----------------EE-WMVSDIRCSSKSSRLQP--------NSGIKS-
L---AGRLGRGQI-PLILLL-----------------FSFLFLAGL--LLI--ILVQVSK
------TPN-----------------------------------------TQG-------
--QEESK-CEEIYQELTQMTNK----LLSKIPTFQRQNESMQ-EISAQLTE-----LKTE
LH-SRISTSQGWNESIK-EISERV----TQLKTELLSR-----------------IPS--
---------------------F------------------------QVQNDSK-----QE
KI--YQQVVKMKAEL---------------------------------------------
---SRLC--RPCPWD-----WTFLLG-NCYFVSKS-QRNWNNAVKACQEVEAQLVIIKSD
EE-----------------------------------------------QTFLQQ--TSK
AKGPTWMGLS--D--LNKEATWLWVD-GSPLS------SRFQKY----WNRGEPNN----
V------GEEDCVEFSG--DGWNDSKCEL-QKF--WICKKPATP-CTAG-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTEAK----------
MQPLSSMDD----------------DE-LMVSGSRYSIKSSRLRP--------HSGIKS-
L---AGCSGHSQV-PLVLQL-----------------LSFLFLAGL--LLI--ILFQVSK
------TPN-----------------------------------------TER-------
--QK--E-QEKILQELTQLTDE----LTSRIPISQGQNESMQAKITEQLMQ-----LKTE
LL-SRIPIFQGQNESMQEKISEQL----MQLKAELLSK-----------------ISS--
---------------------F------------------------PVKDDSK-----QE
KI--YQQLVQMKTEL---------------------------------------------
---FRLC--RLCPWD-----WTFLLG-NCYFFSKS-QRNWNDAVTACKEVKAQLVIINSD
EE-----------------------------------------------QTFLQQ--TSK
AKGPTWMGLS--D--LKKEATWLWVD-GSTLS------SRFQKY----WNRGEPNN----
I------GEEDCVEFAG--DGWNDSKCEL-KKF--WICKKSATP-CTEG-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MDENQ--YSVPEEFFE-FP-RKRCC------
--------RRG-L-QLVLLGL----------------LTVALWAGL--LTL--LLLWHWD
T--------------LKNVKQLEVAAAQN------VSRIAKELHRHQSDRT---------
--AQKSQ-AALMSQTVHELQ----------------------------------------
----------------------------------AEQKQLKSQG----------------
-------SELSSTLDRLQEDLS------S-----VKSQ-----NLNEKHTALDSLGRLKE
EV--AKLWMEIQAS----------------------------------------------
--KGSAC--NTCPEQ-----WVNFQQ-KCYYFGKG-PKQWIQARFSCEDLEGRLVSIHSQ
EE-----------------------------------------------QDFLTKH-A--
NKEDSWIGLR--D--LDIEGEFIWTD-GRPVD---------YSN----WQPGEPNNA---
-----D-QGEHCVMMLG-SGGWNDAFCRS-QLD-AWVCEQLAAC-GS-APPSDPTD---D
SVDAGSASL--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGHRVHWSRRPL-FLALAVL----------------VTTVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLGGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCRSCCSGT-QAQLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCANASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKIQGYQWVD-GVSLS---------FSH----WNRGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------RGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKAAVSELS-EKSKLQEIYQELTRLKAAVGEL-------
--P---------------------------------------------------------
------------EKSKLQEIYQEL----TRLKAAVGELPEKSKQQEIYQELTQLKAAVDG
LPDRSKQQEIYQELTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAG----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHNSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNHEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSGDEEQLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----RLC--RPCPWD-----WTSFQG-NCYFFSKS-TRNWTDSVIACKETGAQLVVIKSH
EE-----------------------------------------------QNFLQL--ISK
NKGHTWMGMS--D--LNTEATWRWVD-GSPLL------PAFMKY----WNPQEPNN----
L------GEEDCAEFDG--NGWNDDNCDV-NNF--WICKKPAAS-CPNQ-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDANGYSKLGSATKE-VT-GGH--------
-WGRWESCKQRLF-FLALAVL----------------VVTVLWALI--LSA--LLSKG--
---------------------------------------STERRTLRHYHS---------
--LLKTN-VSEQKVLLGALKEE----VGACKSCCSET-KAQLQ-------T-----TLTE
L-------------------------------------------KETQAKLMEQESTL--
--------------KELREH-----------------------VTQGLAEAGRDREDVRN
EL--FRALDAVKHQN---------------------------------------------
----SSC--EQCPAS-----WLPFQG-SCYYFSES-QATWEAAQSHCAGHSAHLVIVGGL
DE-----------------------------------------------QGFLTRH-T-R
-SRGYWLGL-RAVRHLRKIQGYQWED-GVSLT---------FSH----WNTGEPNDS---
------RGREDCVMMLHSG-LWNDAPCSS-EKD-GWICEKRSSC-CL-------------
-----------------------------------------------------

---------------------------------------------------------MRL
RRSCVWG--------YKASVQKESREG--G-------AGEQRMAEISDLK---------S
S-----ESP----------------EE-VTFWGLKLAEKDPGLLR--------TR-RVRV
F---PGCLARVPP-SL-PLLL---------ASLVF----FVLLVTT--LVQ------VSR
IHHQSFRAGSWDC-------------------Q--------K-D---R--S--S------
---------------------A--A-V---S---------P--E--Q---I--H---S--
-G-------L--E----E-I-----------R----------------QQLDWMNKTL--
------------------------------------------------------------
------------------------------------------------------------
---VGLC--RPCPWN-----WEFFQG-SCYFFSWT-KGIWKASESACERLGTQLVIINNA
EE-----------------------------------------------QEFLKFW-TIR
RNTRIWIGLS--D--HHVEDSWHWVD-NSSVQ------LSF-------WMEGEPNN----
H------ENEDCVELTN--DGWNDNKCTV-ENF--WICEKRSNP-CPGF-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRWVHWSRRPL-FLALAVL----------------VATVLWALI--LSI--LLSKA--
---------------------------------------FTERAALLGCQD---------
--LLRKN-ASKQTAALGALKEE----VGVCRSCGSRT-QTQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEAGRDREDVRP
GL--FLALEAVRLQN---------------------------------------------
----SAC--EPCPKS-----WLPFGS-SCYYFSVP-K-TWAEAQGHCADASAH---LGGL
EE-----------------------------------------------QDFLSHH-T-S
-ALEYWIGR-KAVQHLCKVQGSSWVD-GVPLS---------FSH----WLQGDPSES---
------WGCEACVMILGTG-LWMDPPCDE--KA-GWICEKRHGA----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAGECEPK---------V
P-----GGP----------------EE-DIFRDQRFTKKDPEVST--------RG--PRS
C---PVSWGRQPL-LL--LLS---------LSLAV---CFLLLVTT--LVQ------VSR
IS-KSPQVEAQDQ-------------------Q--------E-N---P--S--S--G---
------------------E--V--P-A---S---------Q--D--Q---V--Y---S--
-G-------L--E----Q-I-----------L----------------QQLSQINTSL--
------------------------------------------------------------
------------------------------------------------------------
---ARLC--RPCPWT-----WEPFQG-SCYLFSGT-QGTWESSVSACRAVGAHLVIINST
AE-----------------------------------------------QRFLRYW-NIR
KNKVTWIGLT--D--HRTEGSWHWVD-DTPLQ------LSF-------WSKGEPNN----
R------GDEDCAELQD--DAWNDNACSA-ENF--WICEQPSAP-CPGS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHE--Y---SGYWE-PP-RKRCCC-----
-------ARRG-T-QLALVGL----------------LSTAMWAAT--LTL--LLLWHWE
T--------------EKNLKQLGDVAIQN------ISHVSKDLQRYQSNQL---------
--AQKSQ-AVQMSQSMQELQ----------------------------------------
----------------------------------AEQTQMKAQDSELSQNLTRLQEELNN
VESL--NSELSQNLNRLQEDLI------N-----VKSQ-----GLNEKRVASDSLEKLQE
EV--AKLWIEMLTS----------------------------------------------
--KGAAC--STCPKN-----WLHFQR-KCYYFGKG-SKQWIQARFACSDLEGRLVSIHSQ
EE-----------------------------------------------QDFLMKH-I--
NK-DAWIGLR--D--LNVEGQFIWMD-GSPVG---------YSN----WSPGEPNNA---
-----E-QGEDCVMMRG-SGQWNDNSCRS-FLD-AWVCEQLATC-EA-SAPSASVS---P
TGPTPSNEP--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-M--HQKLDQLKTGL---------------------------------------------
---DHLC--RPCPWD-----WTFFQG-NCYFFSTF-QKKWKESVIACKDMGAQLVVIKSY
EE-----------------------------------------------QSFLQR--TSK
MKGNTWIGLS--D--SQEEDQWLWVD-GSPLQ--------WRNY----WSAGEPNN----
L------YDEDCVEFSS--YGWNDISCSF-EKF--WICKKSASP-CPR------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
MQPLDSMED----------------GE-MEVSGSRYSIKSSRLRP--------NSGIKS-
L---AGCLGHNQA-PLVLQL-----------------LSFLFLAGL--LLI--ILFQVFK
------TTN-----------------------------------------TQW-------
--QEEPK-QEKILEELNQLTDE----LMSRIPISQGQNESMQEKISEQLTQ-----LKVE
LL-SRIPVFQVQNESMQEKISEQL----TQLKAELLSK-----------------IPS--
---------------------L------------------------QVQDESK-----QE
KI--YQQLVQMKTEL---------------------------------------------
---LRLC--RLCPWD-----WTFLLG-NCYFLSKS-QRNWNDAVRACKEEKAQLVIINSD
EE-----------------------------------------------QTFLQL--TSK
AKGPTWMGLS--D--LKNEATWLWVD-GSTLS------SRFQKY----WNRGEPNN----
I------GEEDCVEFAG--DGWNDSKCEL-KKF--WIFKKSATA-CTEG-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------CM-HTHLHF-----------------LK-----------------RVSN
------VAY-----------------------------------------SQG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQAK-----KE
KV--YQDVAQLKPQI---------------------------------------------
---NHLC--RPCPWD-----WTFFQG-NCYFFSKF-QQNWKDSVTSCRKLGAQLVVVKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMVLS--D--LKREGIWHWVD-GSHLL------FSFTKY----WNKGEPNN----
E------WEEDCAEFRG--DGWNDAPCTN-KKY--WICKKSALS-CTGK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTGGYSKLGSAIEE-VP-QGQ--------
-LGRWEYYKQRLF-FLVLAFL----------------VATVLWVLI--LST--LLSKA--
---------------------------------------SNERRALLSHQD---------
--LLKTN-ASEQNMMLSALKED----VRGCRNCCSGI-KAQLQ-------T-----TLAE
F-------------------------------------------KDTRAKLMEQESAL--
--------------KELQDR-----------------------VTQGLAKAGRDREDIRN
EL--LRALEAVKQQN---------------------------------------------
----RSC--EQCPTS-----WLFFQG-SCYYFSET-QAVWDTAQSYCSAHGAYLVIVKGP
EE-----------------------------------------------QGFLSQH-T-R
-GRGYWLGL-KAVRRLGKIQGYQWVD-GVSLT---------FSN----WNSGEPNDS---
------RGQEDCVMMLHSG-LWNDAPCTN-ERD-GWICEKRSIC-YP-------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGP--------
-WGRWVHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGHD---------
--LLRTN-ASKQTAALGALKEE----VGDCHSC---------------------------
--------------------------------------------------LMEQESAL--
--------------RELRER-----------------------VTQGLAEAGRGREDVRT
EL--FRALEAVRLQN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNKGEPNDA---
------WGRENCVMMLHTG-LWNDAPCDS-EKD-GWICEKRRNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHS--YS---EFPK-FS-RRRRCC-----
--------GHR-V-QLALLGL----------------ATILLWAGL--LTL--FLFWHWD
T--------------VQNLKQLEVTAAQNAAP---VSRVSKDLERHNGDQM---------
--AQKSQ-AAQVSQNMEEIR----------------------------------------
----------------------------------AEQKRMKAQDSELSRNLDGLRSDLSN
LKSL--SEPWEGMGGRRGVVAA------S--SSLTTVPHPITQGLNERHTALRSLERLQE
EM--VKLWIELHAS----------------------------------------------
--NGSMC--NTCPEK-----WVNFQR-KCYYFGKD-PKKWIQARFACSKLQGRLVSIHSE
EE-----------------------------------------------QDFLAKR-A--
NRKGTWIGLR--D--LDREGEFIWMD-KDPLN---------YSN----WRPGEPNNG---
-----G-QGEDCVMMQG-SGQWNDAFCGS-QLD-GWVCERLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MAEN----QYSG--ER-FP-RKRRC------
--------RRG-L-QLALLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------LRNFKQLEVTAAQN------VVGGGDGA--RPSMTL---------
--SLRSP-AALMSQTVQELR----------------------------------------
----------------------------------AQQQQMKSQGERLVGDT-------RF
SHPS--DSELSWNLDRLQEDMS------S-----IKSQ-----NLNERRSALDSMGRLKE
EV--AKLWMEIQVS----------------------------------------------
--KGSEC--STCPKQ-----WVNFQQ-KCYYFGEG-PKQWVQARFTCNDLEGRLVSIHSQ
EE-----------------------------------------------QDFLTKH-A--
NKEGSWIGLR--D--LDIEGEFTWMD-GSPLD---------YSN----WQSGEPNNA---
-------QGEDCVVMQG-SGQWNDAFCRT-WLD-AWVCEQLATC-GP-PTPSDSTD---N
SP----GSGST---------------HSP------------------------

------------------------------------------------------------
------------------------------------------MNDTKAAR----------
VQPLDPLEE----------------ED-LIGGSPRDSRTDFGLGR--------VQGLKS-
F---AGHLGRHR--HLLLQF-----------------LCFTLFTVL--LVA--ILAQVSK
------VRS-----------------------------------------CHK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QELSK-----EG
EI--VQDLRQLKAGV---------------------------------------------
---AHLC--RRCSWD-----WTFFQE-HCYFFSKS-QRNWHDSLSACQEMGAQLVIVQSA
EE-----------------------------------------------QSFLQQ--TSK
SKGSTWMGLS--D--LNKEATWHWVD-GSALL------LSFMKY----WNPGEPNN----
H------GEEDCGEFSG--NGWNDNKCEV-ENF--WVCKQPANS-CADN-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------V--------RAQQID-
S---LGFLGKGHI-PVMLHL-----------------FFLILFTGL--LVA--IITQISK
------FSS-----------------------------------------LE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------LEQEQRK-----QE
KI--YQDVNQLKSGV---------------------------------------------
---DSLC--CPCPWD-----WTFFHG-NCYFFSKS-QRNWHDSITACQEVGAQLVVIKSH
EE-----------------------------------------------QSFLQW--NAK
KYGYTWMGLS--D--LNKEGTWIWVD-GSPLS------NSLKKY----WNQGQPNN----
N------GGQDCVEFRK--SGWNDASCDN-TKF--WICKSSATP-CSRKW----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSYTAEPR----------
VQQLSSPED----------------ED-CLISGTRHSVVSSGLRP--------NFGIKS-
L---AEYLKCSCN-PLVLQL-----------------LSFLFLAGL--LLI--ILILVSK
------VPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SQD-----QD
RI--YQELKQLKTEV---------------------------------------------
--HDGLC--QPCPRD-----WVFFHR-SCYFFSKS-QRNWHNSITACQEVGAQLVIIETD
EE-----------------------------------------------QTFLQQ--TSK
AKGPTWMGLS--D--VHNEATWHWVD-GSPLS------PGFVKY----WNKGEPNN----
V------GDEDCAEFSS--DGWNDIKCDT-LNF--WICKKALTSSCTTK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTAGYSKWDGRQEE-VP-GEY--------
-SGR---WGQRPL-FLVLALV----------------VITVLWALI--LSV--LFSKA--
---------------------------------------STERGALLGHQD---------
--LLSTN-ASKQTAVLGILKEE----VRACNSCCLGT-QTQLQ-------T-----VSKE
L-------------------------------------------AEARSKLLEQESAL--
--------------KELSER-----------------------VTRSLAEAGRDRENIRT
EL--FRALEQARLGN---------------------------------------------
----SSSC-KECPES-----WLPFQG-SCYFFSTL-RATWVEAQQHCERSGAHLVIVGGL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRKVRRIQGYQWVD-GVALS---------FSH----WNRGEPNDS---
------MGREDCIMMLRTG-MWNDAPCNN-END-NWICEKRLSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEERS--YXXXXXXXX-XX-XX---------
----------X-X-XXXXXXX----------------XXXXXXXXX--XXX--XXXXXWD
M--------------EKNLKHLEGSARQN------VSRVSKDLERHKSDQM---------
--AQKSQ-AARMLASIEHIR----------------------------------------
----------------------------------AEQKSMQSQEGELSQNLDVLGADLDN
LKAK---------------------------------------SLNEKRDASETLWRLQE
EV--AKLWMELXXX----------------------------------------------
--XXSAC--NICPEQ-----WIHFQK-KCYYFGRSKPRKWIQAKHACSDLQGRLVSIHSS
QE-----------------------------------------------QDFLSRH-A--
SKKGSWIGLQ--D--LDREGEFVWPD-GSPVD---------Y------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQQLDLLEE----------------DP--TTSGIRLFPRDFQFQQ--------IHGHKS-
S---TGCLGH--G-ALVLQL-----------------LSFTLLAGV--LVA--ILVQVYK
VPSSLSQEQSEQDTIYQNLTQIKAAVGELS-EKSKLQEIYQELTQLKAAVGE--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------LPEKSKLQEIYQELTQLKAALGELPDQSKQQQIYQELTDLK
TAFERLC--CHCPKD------TFFQG-NCYFMSNS-QRNWHDSVTACQEVRAQLVIIKSA
EE-----------------------------------------------QNFLQLQ-TLR
SNRFSWMGLS--D--LNQEGTWQWVD-GSPLS------PSFQRY----WNSGEPNN----
S------GNEDCAEFSG--SGWNDNRCNV-DNY--WICKKPAA--CFRDE----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDNSGYSKWDSSSEE-VP-RGH--------
-RGCWESWGHKSV-LVALALV----------------VTAVLWALV--LSI--LLSKA--
---------------------------------------STEREVLLDHQD---------
--LLWTN-ASKQKEALGVLAKE----VTVCRTCCSEA-KAQLQ-------T-----TRDQ
L-------------------------------------------GEAQKKLLEQESAL--
--------------NELRQT-----------------------VTTDVAQASRDRENIRN
EL--LRALEAAKLGN---------------------------------------------
----XXX--XXXXXX-----XXXXXX-XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XX-----------------------------------------------XTFLSQN-T-A
-GRGLWLGL-RAVRRERKVLHYQWVD-GLQLT---------FSQ----WNQGEPNDS---
------RGMEDCVMMLHNG-LWNDAPCTN-ERD-NWICERRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MNPP--S---QEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------TQTVKQLEERAARN------VSQVSKNLERHHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNAASDLLERLRE
EV--MKLRMELQVS----------------------------------------------
--NGFVC--NMCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EEQVGPGSAEVVGSTVKVGTPPQLYPT-SRSGLEGPGHMSSVLQPRPAPQDFLTKH-A--
SHTGSWIGLR--N--LNLKGEFIWVD-GSPMD---------YSN----WAPGEPTSQ---
-----S-QGKDCVMMRG-SSHWNNAFCDR-KLG-AWVCDRLATC-AP-PASEGSTE---S
L--GPESRSSP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
-------------------------MGRKEKS--RRDREGA--TFISMPR----------
A------------------------GHLLTMDTVGYSKWDSRLEE-VP-GGY--------
-WGS---WGRRLL-FLGLLLV----------------VATVLWALI--LSV--LVSKA--
---------------------------------------STERGTLLGHQN---------
--LLRTN-ASEQTAALGNLNQE----IRACNSCCLGT-QALLQ-------R-----TRTE
L-------------------------------------------GEAQAKLIQQESVL--
--------------KELSDR-----------------------VTQSLAEAGRDREDIRS
EL--FRALEAARLGN---------------------------------------------
----SSC--EECPES-----WLPFQG-SCYLFSVQ-RATWEESQRNCAGAGAHLVIVGDL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRRGRTIQGYQWVD-GVPLS---------FSH----WNMGEPNDS---
------MGREDCAMMLRTG-MWNDAPCEN-ERD-NWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTEAR----------
MQQLGSMED----------------EE-WMVSDTRCSNKSSRLRP--------HSGTKS-
L---AGCLGRGQI-LLVLHL-----------------LSFLFVAGL--LLI--ILVKVSK
------TPN-----------------------------------------TQG-------
--QEESK-HEEIAQELTQLKDQ----LFSQG-----R-----------------------
------------NE--SSQISEQL----MQMKAELLSS-----------------ILN--
---------------------V------------------------QVQNHSK-----QE
KI--YQQLVQMKAEL---------------------------------------------
---FRLC--RPCPWD-----WTFLRG-NCYFVSKY-QQNWSSAVKACQEVEAQLVIIQSD
EE-----------------------------------------------QSFLQQ--TSK
AKGATWMGLS--D--LKKEGSWLWVD-DSPLS------SRFQKY----WNRGEPNN----
I------GEEDCVEFAG--DGWNDSKCDL-QKF--WICKKSATP-CTESQ----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEMG----------
KKQLGPLDE----------------EQ-LVTGPTRYSIKGFGFQP--------NSGFSS-
F---TGHLGLNHV-PLALQA-----------------FFLIVFSVL--LLV--ILVKVYK
------IPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S------------------------QGQEQSI-----Q-
EV--YQELIQLKAGV---------------------------------------------
---DRLC--RPCPWD-----WTPFQG-SCYFFSVS-QKTWNDSATACQNMGAQLVVIKSD
EE-----------------------------------------------QNFLQQ--ASK
KRGHTWMGLI--D--INNEATWHWVD-GSPLT------LSFMKY----WNKGEPNN----
L------GEEDCAEFRD--DGWNDTKCYN-KKF--WICKKPKAS-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------TQNLKQLEERAAQN------VSQVSKNLERQHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNTASDLLERLRE
EL--TKLRMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTISWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPASQ---
-----S-HGKDCVMMRG-SSHWNNAFCDR-KLG-SWVCDRLATC-AP-PASEGSAE---S
L--GPESRPGP-------------DGRLSA-PS-------APLHS--------

------------------------------------------------------------
---------------------------------------------MEPEA---KWNSYSD
QVEIRRMSPR-----------------------------SQGFTK-LP-GQKTCG-----
--------KSM-Y-LLIFVLL----------------ISVVLWGTL--LFL--FLIRYKE
I--------------TQDLEKLQKSCVPH--N---DSGTVTIIKQLQVDQW---------
--DFKNN-ISQLSKTLNKLQ----------------------------------------
----------------------------------EDQTTMRSKGTQVSDQLD--------
---------------RLEKDST------A-----FKSQ-----VLNEKNDANQAREKLQE
EI--QKLWMEFHKANASRLPPRLD---------------------------SLEEDPTAK
PTQGSVC--TNCPED-----WQLFQK-KCYFFGKE-PKTWSQAKFACINLQSRLVSIKSR
EE-----------------------------------------------QSFLTKN-A--
NNKGCWIGLR--D--LDREGEFQWMD-ESPLN---------YTN----WSPGEPNNQ---
-----G-QGEDCVAMRPFNGKWNDAYCRG-YQD-SWICEKLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPS----------
VQQLGLLEE----------------EQ-L---------RGPGFRQ--------TRGYKS-
L---AGCLGH--G-ALVLQL-----------------LSFTLLAGL--LIQ------VSK
FPSSISQEQSKQDAIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSK-QQEIYQELT-------------------------------------------
-----------------------------RLKAAVGELPEKSKQQEIYQELTRLKAAVGE
LPEKSKQQEIYQELTQLKAAVG------------------------ELPEKSQ-----QQ
EI--YQELTRLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRDWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFAWMGLS--D--LNQEGTWQWVD-GSPLS------PSFKQY----WNRGEPNN----
I------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEEQFLSP---A
P----AT---------------------RN-PP-------PA-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTIRYSQWGGSSKG-VP-TGP--------
-WGSR------VF-FLALAVL----------------LVTVLWALI--LSV--LLSKA--
---------------------------------------STERGVLFGHQD---------
--LLREN-ASRQTAALGALKGE----VGACQSCCNAT-QAELRA------------AVAE
L-------------------------------------------SEARVKLMQQKSAL--
--------------EELSQR-----------------------VTQDLATAGRDRENIRN
EL--FRALEDVKLKN---------------------------------------------
----RSC--EQCPTS-----WLPFRG-SCYYFSEP-RATWEEAQRNCAGNAAHLVIIGDL
DE-----------------------------------------------QGFLTRH-T-R
-GRGYWLGL-RTVRSNGQVHGYKWVD-GVRMG---------FSH----WNTGEPNDA---
------QGQEDCVMMLHSG-LWNDAPCSS-ERD-GWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKESR----------
LQQLDLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLS--QSKQDAIYQNLTQLKAAVSDLP-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-----------------------------------------------------
----------------QQEIYQEL----TRLKAAVGELPEKSKLQEIYQELSRLKAAVGD
LPEKSKQEEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNQEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--SGWNDDKCNL-AKF--WICKKSAAS-CSGDEERLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
AQPLGLLEE----------------EE-LITSSMNFFPRDFGFRQ--------TRGYKS-
L---AGCLGH--T-PLVLLL-----------------LSFMLFTGL--LVA--ILIQVSK
NPSSQRQEH----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------M-----Q-
EI--SQDLTQLK------------------------------------------------
AAVERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSVTACREVGAQLVIIKSD
EE-----------------------------------------------QNFLQLQ-SSR
SNRLAWMGLS--D--LHEENTWQWVD-GSPLS------PSLKRY----WNQGEPNN----
I------GEEDCAEFNG--KGWNDDRCSV-AKF--WICKKSAAS-CSRDEGWLLSS---V
S----AP---------------------LT-AH-------AA-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----QLC--RPCPWD-----WTFFQG-SCYFFSDS-QRNWHDSITACQDVGAQLVIIKGE
EE-----------------------------------------------QNFLQLQ-SSR
RNRFSWIGMS--D--LTHEGSWQWVD-GSPLP------P---------------------
----------------------NDQKCDI-ARF--WICKKSAAS-CSSEEGRFPPS---A
P----AA---------------------PT-LS-------AER----------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLDLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKAAVGDLP-EKSKQQEIYQELTRLKAAVGDL-------
--PEKSK-LQEIY---------------------------------QELTR-----LKAA
VGE-------LPEKSKQQEIYQEL----TRLKAAVGELPEKSKQQEIYQELTRLKAAVGD
LPEKSRQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAAMV--IVW---------------------------------CEFP--
RPTERLC--HPCPWE-----WTFFQG-NCYFISNS-QRNWHDSITACQEMGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNQEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEERLISP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------THM-HTHIQF-----------------LK-----------------RVSS
------IAN-----------------------------------------SKG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQAE-----KE
KV--NQEMTQLKPQI---------------------------------------------
---NRLC--RPCPWD-----WTLFQG-NCYFFSKF-QQNWHDSVTACREVGAQLVVIKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMGLS--D--LKHEGVWHWVD-GSHLL------FSFMKY----WNKGEPNN----
E------GEEDCAEFRD--DGWNDVPCTV-EKY--WICKKSATS-CTKK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTAGYSKWDGRQEE-VP-GGH--------
-SGR---WGQRPL-FLVLALV----------------VITFLWALI--LSV--LFSKA--
---------------------------------------STERRALLGHQD---------
--LLSTN-ASKQTAVLGILKEE----VRACNSCCLGT-QTQLQ-------T-----VSKE
L-------------------------------------------AEARSKLLEQESAL--
--------------KELSER-----------------------VTRSLAEAGRDRENIRT
EL--FRALEQARLGN---------------------------------------------
----TWSRWFQLGPG-----WGGGGM-SCYFFSTL-RATWVEAQQHCERSGAHLVIVGGL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRKVRRIQGYQWVD-GVALS---------FSH----WNRGEPNDS---
------MGREDCIMMLRTG-MWNDAPCNN-END-NWICEKRLSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTSRYSKWGGGPEE-VP-GGY--------
-WGRWEQWRRRSC-FLALVLL----------------AVAVLWALI--LSI--LLSKA--
---------------------------------------STERAALLDSQD---------
--LLRTN-TSKQTAVLGTLKEE----VSACHSCCSRT-QAQLQ-------A-----TRAE
L-------------------------------------------GETQGKLTQQESAL--
--------------KGLQER-----------------------VTQGLAEAGRDREDVRN
EL--FRALEAVRHQN---------------------------------------------
----SSC--DPCPKS-----WLPFEG-SCYYFSVP-QATWVEAQRHCAGAGGYLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHQNKVQGYQWVDGG-PLS---------FSH----WNRGEPNDS---
------WGRENCVMMLHTG-MWNDAPCDS-ERD-GWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDSSGYSKWTGGPKE-AS-AGA--------
-LG---CWGRKLL-WVALAVM----------------VSTVLWALV--LSI--HLSKA--
---------------------------------------STERGLLVDHQG---------
--LR-TN-ASQQAATLGSLQQE----AGACTTCCSEA-RAQLK-------T-----TRAE
L-------------------------------------------GEAQKKLLEQRSTL--
--------------EELRDS-----------------------VTKNVAQAGRDRNTIRT
EL--LRAMEGAKFGN---------------------------------------------
----KSC--EPCPTS-----WLPFGD-SCYFFSEQ-RGNWESAVKSCGNTGAHLVIVNDL
EE-----------------------------------------------QNFLSAN-T-S
-GRGFWLGL-KAVRHLGKIQSYQWMD-GVQLT---------FSH----WNVGEPNDT---
------WRRESCIMMLKSG-WWNDALCGN-ENG-NWICEKRRRC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------WET--GETGPEFLE-SP-RKRRC------
--------RRG-L-QLALLGL----------------LTSALWAGL--LAL--LLLWRED
P--------------TP-------------------------------------------
-----------APLTVQELR----------------------------------------
----------------------------------VEQTQMKSRGERMAGNS-------GP
EP---------------------------------------QGTVRLGHMASDALGKLKE
EV--AKLLMEIQMS----------------------------------------------
--EGSTC--NTCPAQ-----WVSFQQ-KCYYFGES-PKRWLQARYACEDLHGRLVSIHSQ
EE-----------------------------------------------QDFLTKR-A--
NKEKAWIGLR--D--LDIEGEFTWMD-GKPLD---------YTN----WQPGEPNNA---
-----D-QGENCVMMLS-SGKWNDAFCHN-WLD-AWVCEQLATC-GS-PATSDSLD---D
SLDTGST----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------M-G----------------EK----SLPVLKESGQQEQS-PP-QFDP--W----
------------K-FLCLAMT----------------TLMFLLVMI--VGV--VLGNVLL
L--------------N--------------------------------------------
------------------------------------------------------------
----------------------------------------YQLEEELNQ-----------
-----------------------------LNNTFTKGL----------ADARHNRDFIRG
EM--FRQMN------------------------------------------------AVQ
SGNGSSC--TPCPED-----WTAFEG-SCYNFSIN-RLTWIEAKDQCIHAGAHLVIINSL
AE-----------------------------------------------QKFLTTS-Q--
--QEFWIGLT--K--YYRNGLYKWQD-GSSLT---------YTN----WRYENWN-----
--------FYDCVYLMT-SGHWDSDYCGG-YRLYHWICEKPQIC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRRVHWSGRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCRSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELREH-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRFHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
--------------------------T--R-------DSKASMAQHLDPL---------S
KVGSSHSDE----------------EELID----------FEFPR--------NH-SLRS
F---AGCLSQART-HLLLLFL---------LLI------TVLLVAV--LAQXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX----X-XXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXX-XXXX------XXXXXXXXXXXXXXXXXXXXX
XXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-------------------XXX------------------------XXXXXXX-----XX
XX--X-XXXXXXXXX---------------------------------------------
---XGLC--HPCSQN-----WEFFQG-SCYFLSRT-QGTWNTSASACQQQGSQLVIIDSV
EE-----------------------------------------------QRFLQFW-LVK
KDSRTWIGLS--D--HHNEGAWHWVD-NTKLQ------LSFKKY----WNKGEPNN----
K------GEEDCAEFSG--LGWNDNNCGD-RKF--WICKKIAAS-CSRAEGWFLPS---L
P----AA---------------------NP-AA-------GL-----------

------------------------------------------------------------
------------------------------------------MSDSTEAK----------
MQPLSSMDD----------------DE-LMVSGSRYSIKSSRLRP--------NSGIKC-
L---AGCSGHSQV-PLVLQL-----------------LSFLFLAGL--LLI--ILFQVSK
------TPN-----------------------------------------TER-------
--QK--E-QEKILQELTQLTDE----LTSRIPISQGKNESMQAKITEQLMQ-----LKTE
LL-SRIPIFQGQNESIQEKISEQL----MQLKAELLSK-----------------ISS--
---------------------F------------------------PVKDDSK-----QE
KI--YQQLVQMKTEL---------------------------------------------
---FRLC--RLCPWD-----WTFLLG-NCYFFSKS-QRNWNDAVTACKEVKAQLVIINSD
EE-----------------------------------------------QTFLQQ--TSK
AKGPTWMGLS--D--LKKEATWLWVD-GSTLS------SRFQKY----WNRGEPNN----
I------GEEDCVEFAG--DGWNDSKCEL-KKF--WICKKSATP-CTEG-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSESQEPR----------
LQKMGFLEE----------------EQ-L---------RGLGFRQ--------TRVYKS-
L---TGCLGH--G-PLALQL-----------------LSFTLLAGL--LVA--ILVQVSK
VPSSISQGQSKQEDIYQELTQLTAVVGELP-EKSKQQEVYQELIWLKAALGEL-------
--PEKSK-QQEIYQELTQLKAA----V---------------------------------
-GE-------LPERSKQQEIYQEL----TRLKAAVSELPDRSQQQEIYQELSQLKAAVSE
LPDRS-QQQIYQKLTELNAAVV------------------------KLPEKSK-----QQ
EI--YQELTQLKAV----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSVTACQEVGAQLVIIESD
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWIGLS--D--LKQEGTWQWVD-GSPLS------SSLRRY----WNQGEPNN----
I------GEEDCAEFNG--NGWNDDRCSA-AKF--WICKKSAAS-CSRDEERLLSA---P
T----T----------------------SN-PH-------AG-----------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHE--Y---SGYWE-PP-PKRCCC-----
-------ARRG-P-QLVLVGL----------------LSTAMWAGV--LTL--LLLWHWE
T--------------EKNLRQLGDTAIQN------VSHVSKDLQRYQSNQL---------
--AQKSQ-AARMSQSVQELQ----------------------------------------
----------------------------------AEQKQMKVQDSELSQNLNRLQEDLTN
VESQ--NSELSQSLNRLQEDLI------N-----IRSQ-----GLNEKRTASDSLEKLQE
EV--AKLWMEMLIS----------------------------------------------
--KGVAC--STCPKN-----WLNFQQ-KCYYFGKG-SKQWIQARFTCSDLEGRLVSIHSQ
EE-----------------------------------------------QDFLMRH-I--
NKQDSWIGLR--D--LNVEGEFVWMD-GSPVG---------YSN----WNPGEPNNA---
-----G-QGEDCVMMRG-SGQWNDAYCRS-YLD-AWVCEQLATC-EEASAPVASLS---P
TGPTPKNGS--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------CPPS-----WLLFQG-SCYYFSET-QATWDTAQSYCGGQGAHLVIVRGL
NE-----------------------------------------------QGFLSQH-T-R
-GRGYWLGL-RAVRHLNKIQGYRWVD-GASLD---------FRRPWGRWPSSASKRT---
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTGGYSKLGSAIEE-VP-RGQ--------
-LGRWEHYKQRLF-FLVLAFL----------------VATVLWALI--LST--LLSKA--
---------------------------------------SSERRALLSHQD---------
--LLKTN-ASEQKMMLSSLKED----VGGCRNCCSGI-KAQLQ-------T-----TLAE
F-------------------------------------------KDTRAKLMEQESAL--
--------------KELQER-----------------------VTQGLAKAGRDREDIRS
EL--LQALEAVKQQN---------------------------------------------
----RSC--EQCPTS-----WLLFQG-SCYYFSET-QAVWDTAQSYCSARGAHLVIVKGP
EE-----------------------------------------------QGFLSQH-T-R
-GRGYWLGL-RAVRRLGKIQGYQWVD-GVSLT---------FSH----WNSGEPNDS---
------RGQEDCVMMLHSG-LWNDAPCTN-ERD-GWVCEKRSSC----------------
-----------------------------------------------------

----------------------------------------------MAGEPEPQRPKNH-
------------------------------------------------------------
--------G----------------EE-VTFGGKGFAESNPQGLI--------PS--CKK
CL------TRVPW-LL--LLL---------ISLAL----FVLKLAI--LVQ------VSR
IH-GYPQGQTLDQ-------------------Q--------G-S---S--S--L--D---
------------------------A-V---P---------H--E--Q---T--H---S--
-S-------L--E----Q-I-----------Q----------------HQLTQINASLGE
-------------------APG------------------------QRGEENP-----GP
EL--T-HPHCTVCSA---------------------------------------------
---AGLC--RPCPWY-----WELFQG-SCYLFSRT-LGSWEASASACQALGAHLVIVNSI
EE-----------------------------------------------QRFLKFW-HMR
KNELTWIGLS--D--HRREGSWRWVD-DTPLQ------LSF-------WREGEPNN----
D------GDEDCVELGD--DKWNDRRCTA-NNF--WVCEKPSAP-CPGH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEENE--Y---SGYWE-PP-RKRCCC-----
-------ARRG-T-QLMLVGM----------------LSTAMWAGL--LAL--LLLWHWE
T--------------EKNLKQLGDTAIQN------VSHVTKDLQKFQSNQL---------
--AQKSQ-AVQMSQNLQELQ----------------------------------------
----------------------------------AEQKQMKAQDSQLSQNLNKLQEDLIN
VRSQ--NSELSQNLNRLKDDLV------N-----IKSL-----GLNEKRTASDSLEKLQE
EV--AKLWIEILIS----------------------------------------------
--KGTAC--NICPKN-----WLHFQQ-KCYYFGKG-SKQWIQARFTCSDLQGRLVSIHSQ
KE-----------------------------------------------QDFLMQH-I--
NKKDSWIGLQ--D--LNMEGEFVWSD-GSPVG---------YSN----WNPGEPNNG---
-----G-QGEDCVMMRG-SGHWNDAFCRS-YLD-AWVCEQLATC-EL-SAPLASVT---P
TRPTPKSEP--------------------------------------------

------------------------------------------------------------
------------------------------------------MGSSEESK----------
AQQLGPLDE----------------EE-LITSGPRSFMRGLGWQR--------ISGFNC-
S---AGYLGNDSI-PLALQL-----------------LALTLLAGL--LVA--ILVQVSK
------SPS-----------------------------------------FRE-------
--LE--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQSK-----QE
KI--YQELNKLKAGV---------------------------------------------
---DRLC--RPCPWD-----WTLFQE-KCYFFSKS-QRNWNDSSTTCKEKGAQLVIVDSD
EE-----------------------------------------------QSFLQM--ASK
SKGRTWMGLS--D--LNMESKWHWVD-GSLLS------LSLMKY----WNPNEPNN----
L------GEEDCAEFAG--DGWNDARCEV-QKY--FICEQSAAS-CSS------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MHGSTETR----------
MQQLGSVED----------------EE-WMVTGTRCSSKSSRLRS--------NSGIKN-
L---AGCLGH--S-PLVLQL-----------------FSFLFLAGL--LLV--ILVQVSK
------TPN-----------------------------------------TQG-------
--QEESK-LEEIYQELTQLTDK----LLPKTPIPQGQNESMQQKISEQLAQ-----LKTE
LHVSRIPSSQGCNESMQQKIAEQL----TQLKTELLSR-----------------IPS--
---------------------F------------------------QVQNDSK-----QE
KI--YQQLVQMKAEL---------------------------------------------
---FRLC--RPCPWD-----WTFLLG-NCYFFSKS-QRNWNNAVKACQEVEAQLVIIQSD
EE-----------------------------------------------QTFLQQ--TSK
AKGTTWMGLS--D--LKKEATWLWVD-GSPLS------SRFQKY----WNRGEPNN----
I------GEEDCVEFSG--DGWNDSKCEQ-QKF--WICKKSAVP-CTAS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDNSGYSKWSSEPEE-LP-RVP--------
-VGCWRCWGWKSL-LVPLALV----------------VTVVLWALV--LSI--LLSKA--
---------------------------------------STEREALHDHQD---------
--QLWTNAASKQKAALGVLEEE----VAVCRTCCSEA-QEQLQ-------T-----TRGE
L-------------------------------------------GEAQKKLMEQGSAL--
--------------NELREL-----------------------VTKDLAQAGRDREDIRS
EL--LRALEAPKLGN---------------------------------------------
----NSC--EPCPTS-----WIPFEG-SCYFFSSQ-RDTWQEAQKSCADRGAHLVIVGGL
EE-----------------------------------------------QTFLSRD-T-R
-GLGYWLGL-KAVRREGRIKGYQWVD-GVQIT---------FSH----WNQGEPNDS---
------WGKEDCVMMLHTG-LWNDAPCDE-VKD-NWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKDPT----------
AQELGLLEE----------------EE-LKTRGTKFFARDLGFRH--------ACGLKN-
F---AGNMGC--S-SLVLLF-----------------LFFMFLAAF--LVT--ILVQVFK
FHSS--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------LEQEQSR-----QE
EI--YQEVTQLKAEV---------------------------------------------
---DRLC--RPCPWD-----WAFFQG-NCYFFSKI-QRNWHDSMTACQEVGAQLVVIKST
EE-----------------------------------------------QDFLQLQ-TSE
SKHFSWMGLS--D--LTHEGTWQWVD-GSPLQ------SSFMNY----WDKGEPNN----
I------REEDCVEFGS--QGWNDLGCHH-LRF--WNCKKSATS-CQREEVQ--------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MAGHE--Y---AGFLE-PP-RRPCC------
--------RPR-L-PLVLLGM----------------LTALLWAGL--LTL--LLLWHWD
T--------------ERNLRQLEDSAARN------VSQVSKDLHRYQSDQM---------
--AQKSQ-AAQLSRNVERLQ----------------------------------------
----------------------------------AQQTQLESQGERRGRGPGQTVGG---
---------TAPEPQGTRPGDP------R-----APKH-----HLNERRAASDSLEKLQE
EV--AKLWMEILAS----------------------------------------------
--KGTTC--NTCPEG-----WLHFRQ-KCYYFGQG-AKRWVQARFTCDDLEGRLVSIHSQ
EE-----------------------------------------------QDFLTKR-A--
NKRGSWIGLR--D--LDLEGEFIWMD-GSPLD---------YSN----WNLGEPNNG---
-----D-QGEDCVMMLG-SGKWNDASCRG-ELD-AWVCEQLATC-GP-PAPSASGD---V
LEPAPTEGH--------------------------------------------

------------------------------------------------------------
------------------------------------------MCDSKEAR----------
MQPLGSLDQ----------------EE-LITSGTRYSLKSFSYRL--------MSTFSC-
F---AGCQGNDLI-SLIVQL-----------------FFLVLFTGL--LVA--ILAQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---DRLC--RPCPWD-----WTFFQG-KCYFFSKS-KRNWHESITACQEAGAQLVIVEND
EE-----------------------------------------------QSFLQQ--TSK
KKGFAWMGLS--D--LNKESTWRWVD-DSPLA------FSLMQY----WNKGQPNN----
N------NEQDCVEFRG--DGWNDARCDI-KKF--WICKKSVTP-CSNK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------P-R-APPPSALSL
L---PS--QRA-L-VLLYLLL----------------ALGFVILVA--LVI--TNTQK--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------VSQEMENVRWKMAQCKTECGK
ELSE--------RIR------------------AL-------------------------
------------------------------------------------------------
---EILC--TRCPAG-----WLQFAG-TCYLFSTD-AKPWMEAKDSCAGLGGQLAIVNSE
LE-----------------------------------------------NKFLANY-IME
-TRVFWLGLS--D--MHKEGDWQWVD-GRSLS---------LSF----WGSGEPNNV---
-----GQHGEDCATVSS-RGLWNDATCSG-AEA--WICER--------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------M--------RAPQMG-
S---LGFLDKGHI-PLVLQL-----------------LFLILFTGL--LVA--IIIQVSK
------MPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------IQWEHTK-----QE
KM--YKDLSQLKSEV---------------------------------------------
---DRLC--RLCPWD-----WTFFNG-NCYFFSKS-QRDWHDSMTACKEMGAQLVIIKSH
EE-----------------------------------------------QSFLQQ--TSK
KNSYTWMGLS--D--LNKEGEWYWLD-GSPLS------DSFEKY----WKKGQPNN----
V------GGQDCVEFRD--NGWNDAKCEQ-RKF--WICKKIATT-CLSKW----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------RGLGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSISQEQSRQDAIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSK-LQEIYQELTRLKAA----VGELPEK------SKLQEIYQELTW-----LKAA
VGE-------LPEKSKMQEIYQEL----TRLKAAVGELPEKSKQQEIYQELTRLKAAVGE
LPEKSKQQEIYQELTRLKAAVG------------------------ELPEKSK-----QQ
EI--YQELTQLKAA----------------------------------------------
--VERLC--HPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACKEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNQEGTWQWVD-GSPLL------PSFKQY----WNRGEPNN----
V------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEEQFLSP---A
P----AT---------------------PN-PP-------PA-----------

------------------------------------------------------------
--------------------------S--R-------EEQRMEEMDDHND---------P
D-----SHE----------------EK-VTFWGQRFMKKDPRFLR--------SH--DPG
T---GGCLTQVPL-PL--LLL---------VSLGL---VFVFLVTT--LVQ------VFR
IH-QALQSETWDH-------------------Q--------N-A---S--P--L--L---
------------------P--V--A-S---P---------Q--K--Q---I--Q---L--
-E-------L--E----E-I-----------H----------------QQLAWMNAS---
------------------------------------------------------------
--------------L---------------------------------------------
---AGLC--NPCSRN-----WESFQN-SCYFLSRT-RGTWDTSVTACQDQGAQLVIINSV
EE-----------------------------------------------QRFLQFW-IVG
KDTRTWIGLS--D--HHNEGAWHWVD-NTKLQ------LSF-------WTEGEPNN----
V------GDEDCAEMIA--AGWNDNKCTA-ENF--WVCEKPSTP-CPGV-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------CLPG-----WALFQG-SCYLFSST-NGTWQVARNNCLAQGADLVVISEQ
TE-----------------------------------------------QGYLVHR-G--
GSVRYWIGLT--D--QEREGDWRWVD-DTPLT---------LTF----WNRWEPNNLFSP
TPEGKG-EAENCAQLLE-TGLWNDEPCGF-S-Y-TWICE---------------------
-----------------------------------------------------

--------------------------------------------------M---------
-------------------------------------AGKPELHQLNNHE---------E
EV----------------------------------TLEDQGFAENDP-EGLICSS--KS
L---QGH-LTR-A-PWLLLLL----------------ISLGLFLLM--L-A--ILV----
-------------------------------------QVSRICANPQGQTQ---------
--DQKGS-SSLG--KVAVPQEQ--------------------------THT----GLE--
---------------------------------------QIQQIQQIQQQLTQF------
-----------------NASL---------------------------------------
------------------------------------------------------------
---AGLC---PCPWD-----WEFSRE--AYLFSARIHETLATIIQSIISLNIHPHTLPHT
SA-----------------------------------------------KSPQSHSNRTT
PKMRSWIGLS--D--HLREGSWQWVD-HSPLK---------FSF----WKEGEPNND---
-------GDEDCVELFM--DEWNDNTCTQ-QNF--WVCEQPSAP-CPGH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDMAGYSRWDGRLEE-VP-GXX--------
-XXXXXXXXXXXX-XXXXXXX----------------XXXXXXXXX--XXX--XXXXX--
---------------------------------------STERRALLGQQD---------
--LLRTN-SSKQTAVLGVLKEE----VRACNSCCLGT-QAQLQ-------T-----VHTK
L-------------------------------------------REAQSKLIQQESAL--
--------------KELSER-----------------------XXXXXXXXXXXXXXXXX
XX--XXXXXXXXXXX---------------------------------------------
----XSC--EECPKS-----WLPFQG-SCYLFSTQ-RATWVEAQRHCEGAGAHLVIVGGL
DE-----------------------------------------------QVFLSRN-T-G
-GRGYWLGL-RAVRRARRIRGYQWVD-GVPLS---------FSH----WNQGEPNDS---
------LGREDCIMILRTG-MWNDAPCDN-RDD-SWICEKRLSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ--D--PVSK
VPSSLSQGQSKQDAIYQNLTQLKVAVSELS-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-QQEIYQE---------------------------------------------
-----------------------L----TRLKAAVGELPEKSKQQEIYQELSQLKAAVGD
LPEKSKQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHNSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNHEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSGDEERLLSP---T
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MSSQ--N---QGYWE-PP-RKRCCC-----
-------ARRG-T-QLVLVGL----------------LSTAMWAAM--LTL--LLLWHWE
T--------------EKNLKQLGDIAIQN-------------------------------
--------AVQMSQSMQELQ----------------------------------------
----------------------------------AEQTQMKAQDSELSQNLNRLQEELNN
VESQ--NSELSQNLNRLQEDLI------N-----VKSQ-----GLNEKRTASDSLEKLQE
EV--AKLWIEMLIS----------------------------------------------
--KGAAC--STCPKN-----WLHFQQ-KCYYFGKG-PKQWIQARFACSDLEGRLVSIHSQ
EE-----------------------------------------------QDFLMKH-I--
SK-DSWIGLR--D--LNVEGQFIWMD-GSPVG---------YSN----WSPGEPNNA---
-----E-QGEDCVLMRE-SGQWNDYSCRS-FLY-AWVCEQLATC-EA-SAPLASVS---P
TGPTPSNEP--------------------------------------------

------------------------------------------------------------
------------------------------------------MTDSKEAK----------
GQRLGPLDE----------------EE-LIAGGTRYFIKGLGFRP--------TYSFKD-
I---AGGPGHGSR-VLMLQL-----------------LFLVLFTVI--LVV--VLVKVSK
------VPS-----------------------------------------YQE-------
--QK--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QAK--------Q
MI--NNKMNQLKNGI---------------------------------------------
---GRLC--RPCSWD-----WTLFQR-NCYFFSNS-KLNWSNSVTACQEMRAQLVVIKSV
EE-----------------------------------------------QNFLQL--SSK
NRGPTWMGLS--D--LKKEGVWHWLD-GSHLW------FRFTKY----WLPGEPNN----
D------GKEDCAEFRG--DGWNDGKCER-EKF--WICKKPAAS-CSNI-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHS--YSDPAEFPK-FS-RRRRCC-----
--------GQR-M-QLALLGL----------------ATVLLWAGL--LTL--LLFWHWD
T--------------VQNLRQLEVTAARN------VSRVSKDLERHNGDQM---------
--AQKSQ-AARVSQNMEEIR----------------------------------------
----------------------------------AEQERMKAQDSELSRNLDGLRLDLSN
LKSL---------------------------------------NLNERHTALRSLERLQQ
EV--LKLWIELHTS----------------------------------------------
--NGSTC--NTCPEK-----WVSFQR-KCYYFGAE-PKRWIQARFACSKLQGQLVSIHSQ
EE-----------------------------------------------QDFLARH-A--
NRKGTWIGLR--D--LDREGEFIWMD-KEPLN---------YSN----WRPGEPNNG---
-----G-QGEDCVMMQG-SGQWNDAFCGS-RLD-GWVCDRLATC-FPSGSEGGK-K---K
R--GSRCIPPP-------------HPSLPT-VS-------A-----SVDT---

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRRVHWSGRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCHSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRSREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQSHCADASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------LSL--
--------------LDLGLV-----------------------L-------SRGAEPLPT
--------ASSRCFP---------------------------------------------
--PGNSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQRHCADAGAHLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGRENCVMMLHTG-LWNDAPCDS-EKD-GWICEKSAPE-PRPLQHVVSWGLLTS
LAPGADCQRVFSSSSIAAESQKHSAQHSPVQPSAWALGPPCQPHPNSTHAGPT

------------------------------------------------------------
------------------------------------------------------------
---------------------------------TKEA-----------------TQQLG-
P----LGWQDNLV-SPVLQL-----------------LSFVLLAGL--LVA--ILAHASK
------VPS-----------------------------------------RE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------LKKERSN-----QE
KI--YQELNQLKTGF---------------------------------------------
---DRLC--RPCPWD-----WTFFQA-KCYFFSKS-QRDWHESITACQEEGAQLVTVESA
EE-----------------------------------------------QSFLQQ--TSK
SKGSAWMGLS--D--LNKESEWRWVD-GSPLS------LSLTQF----WNKGQPNN----
Y------KGQDCVEFRD--DGWNDAKCDL-KRF--WICKKPAAS-CSSER----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRR-T-QIVLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------TQNLKQLEERAAQN------VSQVSKNLERQHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNTASDLLERLRE
EV--TKLRMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTISWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPASQ---
-----S-HGKDCVMMRG-SSHWNNAFCDR-KLG-SWVCDRLATC-AP-PASEGSAE---S
L--GPESRPGP-------------DGRLSA-PS-------APLHS--------

------------------------------------------------------------
---------------------------------------------MEPEA---KWNGSSD
QVEFSRMSPR-----------------------------SQGFTK-LP-GQKTCG-----
--------KSV-L-LFTFVLL----------------ISAALWGTL--LFL--FITRYQE
I--------------VQDLGKLRESCVYY--N---DSGILTVIGQLQETQL---------
--NLKTN-VPQLSKTLNKLQ----------------------------------------
----------------------------------EDQTTLKSKASQFSQQLN--------
---------------RFEEDGT------A-----FRSQ-----VLNEKNTATQAREKLQE
EI--QKLWIEFQRANGWTVLPSPPSP-----NLT---------ASQLSQGLNRLEDHTAM
PTQGSIC--TKCPEN-----WQVFQK-KCYFFGKE-PKTWAQAKYACINLQGRLVSIKSR
EE-----------------------------------------------QVFLNRN-A--
NKKGSWIGLR--D--LDIEGIFLWMD-GSSLN---------YTN----WGRGEPNNQ---
-----G-QGEDCVAMRGTSGLWNDANCRG-QQD-SWICEKLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRGVHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCRSCCSGT-QAQLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAVAQGHCANASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNRGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGL------------------------------------------------------
--------------------------------------------------L------VSK
VPSSISQEQSRQDAIYQNLTQFKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--P---------------------------------------------------------
------------------------------------------------------------
--EKSKQQEIYQELSQLKAAVG------------------------ELPEKSK-----QQ
EI--YQELTQLKAA----------------------------------------------
--VERLC--RRCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNHEGTWQWVD-GSPLL------PSFEQY----WNRGEPNN----
V------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEEQFLSP---A
S----AT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------MSDSTESK----------
TQQVVIPED----------------EE-CLMSGTRYSDISSRLQT--------KFGIKS-
L---AEYTKQSRN-PLVLQL-----------------LSFLFLAGL--LLI--ILILVSK
------VPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SEV-----QN
KI--YQELMQLKAEV---------------------------------------------
--HDGLC--QPCPRD-----WTFFNG-SCYFFSKS-QRNWHNSTTACQELGAQLVIIETD
EE-----------------------------------------------QTFLQQ--TSK
ARGPTWMGLS--D--MHNEATWHWVD-GSPLS------PSFTQY----WNRGEPNN----
V------GDEDCAEFSG--DGWNDLRCDK-LLF--WICKKVSTSSCTTK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MNPP--S---QEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------TQHLKQLEERAAQN------VSQVSKNLERQHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNTASDLLERLRE
EV--TKLRMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTISWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPASQ---
-----S-HGKDCVMMRG-SSHWNNAFCDR-KLG-SWVCDRLATC-AP-PANEGSAE---S
L--GPESRPG-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEESS--YAEVFEFH---R-SRRQCC-----
--------KLG-M-QIALLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------VQNLKHLEETAARN------VSQVSKALENHKGDQM---------
--AQKSQ-AAQMSQNMEKIE----------------------------------------
----------------------------------AEQKRMKAQDSELSQNLDGLLEDLSN
LKSQ---------------------------------------GLNERRTALNSLERLQE
EV--AKLWIELRVS----------------------------------------------
--NGSTC--NTCPES-----WVNFQH-KCYYFGKG-AKRWIQAREACSKLQGRLVSIHSQ
EE-----------------------------------------------QDFLAXX-X--
XXXXXXXXXX--X--XXXXXXXXXXX-XXXXX---------XXX----XXXXXXNNG---
-----D-QGEECVMMLG-FGQWNDAFCNN-YLD-GWVCDRLATC-VPTCCLGPR-L---D
P-------------------------DSPL-PA-------LFVSPPL-Q----

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQQLGLLEE----------------DP--TTSGIRLFPRDFQFQQ--------IHGHKS-
S---TGCLGH--G-PLVLQL-----------------LSFTLLAGV--LVA--ILVQVSK
VPSSLSQEQSEQDTIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSK-LQEIYQELTQLKAA----VGELPEK------SKLQEIYQELTQ-----LKAA
VGE-------LPEKSKLQEIYQEL----TQLKAAVGELPEKSKLQEIYQELTQLKAAVGE
LPEKSKLQETYQELTQLKAAVG------------------------ELPEKSK-----LQ
EI--YQELTQLKAAVG--ELPEKSELQEIYQELTQLKAALGKLPDQSKQQQIYQELTDLK
TAFERLC--RHCPKD-----WTFFQG-NCYFMSNS-QRNWHNSVTACREVRAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-TSR
SNRFSWMGLS--D--LNQEGTWQWVD-GSPLS------PSFQRY----WNSGEPNN----
S------GNEDCAEFSG--SGWNDNRCDI-DNY--WICKKPAV--CFRDE----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSESKETG----------
KQQLGPLDE----------------EL-LTSSHTRYSMKGFGFQP--------NSGFSS-
F---TGYLVHSHV-PLALKA-----------------LFLTVFSVL--LVV--ILVKVYK
------IPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S------------------------HEQEESN-----QK
NF--YQELIQLKAGV---------------------------------------------
---DRLC--RSCPWD-----WTAFQG-NCYFFSVA-QKSWNDSATACHNVGAQLVVIKSE
EE-----------------------------------------------QNFLQK--TSK
KRGYTWMGLI--D--INKESTWHWVD-GSPLT------LTFMKY----WNKGEPNN----
V------GDKDCAELRE--DGWNDNKCDN-KKF--WICKKPETS-CSSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQQLGLLEE----------------DP--TTSGIRLFPRDFQFQQ--------IHGHKS-
S---TGCLGH--G-ALVLQL-----------------LSFTLLAGV--LVA--ILVQVSK
VPSSLSQEQSEQDAIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSK-LQEIYQELTQLKAA----VGELPEK------SKLQEIYQELTQ-----LKAA
VGE-------LPE-----------------------------------------------
--------------------------------------------------KSK-----LQ
EI--YQELTRLKAAVG--ELPEKSKLQEIYQELTQLKAALGKLPDQSKQQQIYQELTDLK
TAFERLC--RHCPKD-----WTFFQG-NCYFMSNS-QRNWHNSVTACQEVRAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-TSR
SNRFSWMGLS--D--LNQEGTWQWVD-GSPLS------PSFQRY----WNSGEPNN----
S------GNEDCAEFSG--SGWNDNRCDV-DNY--WICKKPTV--CFRDE----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------METVRYSQWDSSPEE-VP-GGH--------
-WGRWEHLRRWVF-SLALAIL----------------AVTVLWALI--LSARDLLSAA--
---------------------------------------STERGALLAHQD---------
--LLRTN-ASKQTAALGALKGE----VGACQSCCETP-AGRGRGLW----V-----GLAA
R-------------------------------------------GLAQVKLTQQKSAL--
--------------EELSLR-----------------------VTQDLATAGRDRENIRN
EL--FRALEAAKLQN---------------------------------------------
----GSC--GQCPTS-----WLPFRG-SCYYFSEP-RTTWQEAERNCVGNAAHLVIIGDL
DE-----------------------------------------------QGFLTRH-T-R
-GRGYWLGL-RAVRSGGRVQGYQWVD-GVSIS---------FSH----WNVGEPNDS---
------QSKEDCVMMLHSG-LWNDAPCSS-ERD-GWICEKRSSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MLAI--LVQ------VSR
IH-GYPQGQTLDQ-------------------Q--------G-S---S--S--L--D---
------------------------A-V---P---------H--E--Q---T--H---S--
-S-------L--E----Q-I-----------Q----------------HQLTQINASL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RPCPWY-----WELFQG-SCYLFSRT-LGSWEASASSCQALGAHLVIVNSI
EE-----------------------------------------------QRFLKFW-HMR
KNELTWIGLS--D--HRREGSWRWVD-DTPLQ------LSF-------WREGEPNN----
D------GDEDCVELGD--DKWNDRRCTA-NNF--WVCEKPSAP-CPGH-----------
-----------------------------------------------------

----------------------------------------------MAGEPEPQRPKNH-
------------------------------------------------------------
--------G----------------EE-VTFGGKGFAESNPQGLI--------PS--CKK
CL------TRVPW-LL--LLL---------ISLAL----FVLKLAI--LVQ------VSR
IR-GYPQGQTLDQ-------------------Q--------G-S---S--S--L--D---
------------------------A-V---P---------H--E--Q---T--H---S--
-S-------L--E----Q-I-----------Q----------------HQLTQINASL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RPCPWY-----WELFQG-SCYLFSRT-LGSWEASASACQALGAHLVIVNSI
EE-----------------------------------------------QRFMKYW-NMR
KNRRSWIGLS--D--HRHEGFWHWVD-DTPLQ------LSF-------WKKGEPNN----
D------EDEDCVELFM--DDWNDNKCTE-ENF--WVCEQPSAP-CPGH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTVGYSKWGGGLEE-VP-GGH--------
-QGR---WGQRLL-FLGLVLV----------------VATALWALI--LSI--LVSKA--
---------------------------------------STERGALLGHQD---------
--LLRTN-ASEQTAALGALNRE----VRACNSCCLGT-QALLQ-------R-----ARTE
L-------------------------------------------GEAQAKLIQQESAL--
--------------KELSDR-----------------------VTQSLAKAGRDREDIRS
EL--FRALEAIRLGN---------------------------------------------
----SSC--EECPAS-----WLPFQG-SCYLFSVE-RATWEESQRQCAGAGAHLVIVGDL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRRARKIQGYQWVD-GVPLS---------FSH----WNVGEPNDS---
------LGREDCAMMLRTG-MWNDAPCDN-ERD-NWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----LRFLDRGHI-SLALQL-----------------LSLVFFAGL--LAA--IVIQVSK
------IPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------IQWEQKK-----QE
KM--FQDLSQMKSEV---------------------------------------------
---DSLC--RRCPWD-----WTFFKG-NCYFFSKS-QRDWHDSITACQEVGAQLVIIKSH
EE-----------------------------------------------QYFLQQ--ASK
KNGYTWMGLS--D--LNKEGAWYWLD-GSPLS------DSFERY----WNEGQPNN----
F------GGQDCVEFRN--DGWNDAKCDD-MKL--WICKKSSTT-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDQGVYSNLNEVSLA-KPMPYR--------
-------TEARARLFLYLFMA----------------GTLVLWAIL--LIV--VLAKA--
---------------------------------------SEASTGLKRLQE---------
--AQTR--------------------------------------------------LNMN
D-------------------------------------------SLAKNKLQTLEDQL--
--------------SDLKSQ-----------------------MTMKLAQAGKDREDIRS
EM--FRALAASKIGN---------------------------------------------
----TSC--TPCSPS-----WKAFEG-SCYYMSRT-TALWHDAVKKCAEKEAHLVIINSR
EE-----------------------------------------------QNFLISN-S-D
-DRTYWIGLSSVRDGSGKVKHHRWID-ETDLT---------FTY----WSPGEPNDA---
------GDQEDCVVMLSNG-RWNDTPCHT-DLE-KWVCEKRQSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDFKEAR----------
VQQLGPLEK----------------GL-MMASGTRSSAEGSGFQL--------TSAFNS-
L---AGCLGHGHI-SLVLQL-----------------LCLTVLAGI--LVA--ALVQVSK
------IPS-----------------------------------------SQE-------
--QE--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QELVK-----QE
KM--YQELTQLKAGV---------------------------------------------
---DRLC--RPCPWD-----WTFFQG-HCYFFSKS-QRNWHDSVITCQEEGAQLVVINSA
EE-----------------------------------------------QSFLQQ--TSD
IQGSAWLGLS--D--LNKEGAWSWVD-GSPLS------LNLTRY----WMPGQPNN----
R------GGQDCVEVRS--RGWKDSKCDY-KKF--WVCKRFAAS-CSTE-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MLAI--LVQ------VSR
VR-ASPQGQTPGQ-------------------Q--------G-S---S--S--L--G---
------------------E--V--A-V---P---------H--G--Q---T--H---S--
-S-------L--E----Q-I-----------Q----------------QQLTQINASL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RPCPWD-----WELFQG-SCYLFSRT-LGSWGASATSCQDLGAHLVIINSV
EE-----------------------------------------------QLFLKYW-HIR
KNERSWIGLS--D--HRHEGSWQWVD-DTPLR------LSF-------WQEGEPNN----
E------GDEDCVELAE--DKWNDRRCTA-NNF--WVCEQPSAP-CPRH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRRVHWSGRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCHSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
---------------------------------------------MCDPA----DPK---
PPELAGLDE----------------DA-LMPSGWSHFSVGTQGSW-SA-RSFPAPWLRR-
---------LG-F-PLLLAFF----------------VLSFIL-----SII--TLTQVFQ
N--------------QR----------LYNSE---QEAVQEKLNYLSAQLK---------
--GDQDL-RDKGQLEASQFIEQ--------------------------LNK----TLN--
------------L-------------------KINNQLE---------------------
------------------------------------------------------------
-A--SKFTE------------------------------------------------QLN
KTLSALC--RPCPCQ-----WKFYKD-SCYYFSVA-QASWETARKACEADGTNLAIISSS
EE-----------------------------------------------QNYLKLN-LDS
NRRPRWIGLS--D--KKKEGTWHWVD-ETALGQ---------SF----WNEGEPNN----
-----A-GDEDCCELIP--NGWNDAPCSK-ENY--WICEKKASP-CPML-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------MTVS-DSKA--------RVQQMG-
S---LGFLDRGHI-ALVLQL-----------------LLLVLFAGL--LAA--IIIQVSK
------IPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------MQWEKTK-----QE
KM--YQDLSQLKSEV---------------------------------------------
---DSLC--RHCPWD-----WTFFNG-NCYFFSKS-QRNWHDSITACQEVGAQLVVVKSH
EE-----------------------------------------------QSFLQQ--TSK
KNGYTWMGLS--D--LNKEGAWYWLD-DSPLS------DRFGKY----WNRGQPNN----
I------GGQDCVEFRD--EGWNDANCND-MKL--WICKKSATT-CSSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MTDSKESR----------
VPQLGLLDE----------------EE-LITSGARNSQKSFGFRP--------KSVLSC-
F---AGCWDNDLI-SLVLQL-----------------LSILLFTGL--LVA--ILAQVSK
------VPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------QEKEKSN-----QE
QL--YQELNQLKTEF---------------------------------------------
---GHLC--RPCPWD-----WTFFQS-KCYFFSKS-QRDWHESITACKEVGAQLVIVEND
EE-----------------------------------------------QSFLQQ--TSK
SKGYAWMGLS--D--LNKESTWRWVD-GSPLS------FSLMQY----WNKGQPNN----
Y------QEQDCVEFRG--DGWNDARCNL-KKF--WICKKPASS-CSNSDDQLPPA---A
P----AA----------------------------------------------

------------------------------------------------------------
------------------------------------------MTDSKDMG----------
KKQLGPLDE----------------EQ-LISSHARYSTKDFSFQP--------NSGFSS-
F---AGHLGLSHI-PLALQV-----------------FFLIVFSVL--LVV--VLA----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------K---------------------------------------------
---DRLC--RPCPWD-----WTPFQG-SCYFFSVV-QKAWNDSATACQKVGAQLVVIKSD
EE-----------------------------------------------QNFLQQ--SSK
KRGNTWMGLI--D--MNKESTWHWVD-GSPLT------LSFMKY----WNKGEPNN----
L------GEEDCAEFKG--DGWNDSKCDN-KNF--WICKKTKTS-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RR-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------TQSLKQLEERAARN------VSQVSKNLESHHGDQM---------
--AQKSQ-STQISQELEELR----------------------------------------
----------------------------------AEQQRLKSQDLELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNEASDLLQRLRE
EV--TKLRMELQMS----------------------------------------------
--SGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWVHARYACDDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTGSWIGLR--N--LDLKGEFIWVD-GSHVD---------YSN----WAPGEPTSR---
-----S-QGEDCVMMRG-SGRWNDAFCDR-KLG-AWVCDRLATC-TP-PASEGSAE---S
M--GPDSRPGP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MDENQ--Y---SEFFE-FP-RKRCC------
--------RRG-L-PLGLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------MRNVRQLEVAAAQN------VSRISKELQSHLSEQL---------
--AQKYQ-AALMSQAVQELQ----------------------------------------
----------------------------------AGQKKQK-------------------
-EPQ--DSELSQNLDRLWEDLS------S-----IKSQ-----NLNERHMALESLERLKE
EL--AKLRVQIQVS----------------------------------------------
--KGSVC--NACPEQ-----WVSFQQ-KCYYFGEE-PKQWLQARYSCEDLGGRLVSIHSQ
EQ-----------------------------------------------QDFLTKL-A--
KKEGTWIGLR--D--LDIEGQFLWMD-GSSVD---------YSN----WQPGEPNNA---
-----D-PGEDCVMLLR-SGKWNDAFCRD-ELD-AWVCEQLATC-GP-SF----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRRVHWSGRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDVQD---------
--LLRTN-ASKQTAALGALKEE----VGVCHSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEMG----------
TKQLGSLXE----------------KL-LTSSHTRHSIKGFGFQP--------NSGFSS-
F---TGCLVHSHV-PLALQV-----------------LFLAVFSVL--LVV--ILVKVYK
------IPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S------------------------QGQEESN-----QK
NV--YQELTXLKAGV---------------------------------------------
---DRLC--RSCPWD-----WTHFQG-NCYFFSVA-QKSWNDSATACHNVGAQLVVIKSD
EE-----------------------------------------------QNFLQQ--TSK
KRGYTWMGLI--D--MSKESTWYWVD-GSPLT------LSFMKY----WNKGEPNN----
L------GEEDCAEFRD--DGWNDTKCTN-KKF--WICKKLATP-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
AQQLGLMEE----------------EE-LMTSNIRSFPRHSGFPR--------TRGFNN-
L---AGRLGH--V-SLVLWL-----------------LSFILFAGL--LMA--ILVKVSK
PPNSLSQEQ----QIFQELAQLKTAIDECP-ARSKQQEISQELAQLKTALNEC-------
--PARSK-QQEISQELAQLKTA----INECPAR------SKQQEISQELAQ-----LKTA
IDE-------CPARSKQQEISQEL----AQLKTAIDECPARSKQQEISQELAQLKTAINE
CPARSKQQEISQELAQLKTAVG------------------------K----CK-----QP
EI--AQEVAQLK------------------------------------------------
VAVNHLC--RPCPWD-----WTFFQG-NCYFISNS-QRNWQDSITACQEVGAQLVVIKSH
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LKTEGTWHWVD-GSLLS------PSFAKY----WNRGEPNN----
V------GKEDCAEFSG--NGWNDDKCAV-AKF--WVCKKPAAS-CPHEEGWFLSS---T
P----AV---------------------PS-PA-------AG-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MRM-HTHLQF-----------------LK----GGI-------KHDALSN
------VAY-----------------------------------------SQE-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QERTK-----KE
KV--YQEMTQLKPQI---------------------------------------------
---NLLC--RPCPWD-----WTVFQG-NCYFFSKS-QQNWNDSVTACRKLDAQLVVIKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMGLS--D--LKHEGTWHWVD-GSHLL------FSFMKY----WNKGEPNN----
E------REEDCAEFRG--EGWNDAPCTI-KKY--WICKKSAMS-CAEK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MDSQS--Q---GF-SE-SP-RKRCC------
--------GRE-T-QLALMGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------LRDMKQLEEAAARN------VSQVSKDLQRYQGDQM---------
--AQKSQ-ASEMWQMLQELR----------------------------------------
----------------------------------SNQK-TRTQDSGLSWDLD--------
---------------RLREDLS------N-----FKSQ-----SLNERRTASDLLERLQE
EV--AKLWMEILVS----------------------------------------------
--NGSSC--NTCPEN-----WVHFQR-KCYYFGEG-SKQWIHARYACDNLQGRLVSIHSQ
EE-----------------------------------------------QDFLAKH-V--
SKRGSWIGLR--D--LDIEGEFIWVD-GSRMD---------YSN----WHPGEPNNG---
-----G-QGEDCVMMQG-SGLWNDAFCRS-LLD-AWVCERLATC-GP-RRA---------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTAPYCRWGGGLEE-AL-GGS--------
-WGR---WGRRLL-FLVLSLM----------------VATVLWALI--LTV--LFSKA--
---------------------------------------STERGVLLGHQD---------
--LLRTN-ASRQTAVLAALKEK----VSVCNSCCQET-QAQLQ-------T-----ARTE
L-------------------------------------------GEAREKLFQQESDL--
--------------KELSER-----------------------VTQGLAEAGRDREDIRT
EL--LRALEAARLRN---------------------------------------------
----SSC--EQCPAS-----WLPFQG-SCYFFSEI-TATWDEAQRRCVGASAHLVIVRGL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRRARKIQSYQWVD-GVSLS---------FSY----WNQGEPNDA---
------QGREDCVMMLRTG-MWNDAPCNS-ERD-SWICEKRQSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLGE----------------AG-CPMV-----PTSMES-----------------
-----GR-----T-----------------------------------------------
-----PAPR----LIYQNCHQLKAAVCEAL------------------------------
------------------------------------------------------------
-----------------------------------RENPRWQE-----------NLPVGE
LPEKSRSTQ----------GDL------------------------P----GA-----DP
ES--LQELTRLKAAVP--------------------------------------------
PPTERLC--RRCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACKEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNEEGMWQWVD-GSPLL------PSFNQY----WNRGEPNN----
V------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEEQFLSP---A
P----AT---------------------PN-PP-------PA-----------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------ARTARP--------SS-----
----LRVSGPGPC-PLVLLL-----------------FFLPFITVL--------------
WWLSWSKRV---------------------------------------------------
------------------------------------------------------------
--------------------SS----------TVPSNP-----------------LVQ--
---------------------L------------------------QGLEHSK-----QE
EI--YQKLTQLKAGV---------------------------------------------
---DCLC--HPCFWE-----WTFFQG-NCYFFSNS-QWNWYDAITACQEVGAQLVVIKTA
EK-----------------------------------------------QNFLQVQ-TST
SNLFTWIGLS--D--LKHEGIWHWVD-GSSLL------LSFMKY----WNKGEPNS----
S------GEEK-AEFRG--EGWKDSKCDN-SKF--WICKTTAAS-CSSN-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEQR----------
AQPLGLLEE----------------EE-LITSSMNFFPRDFGFRQ--------TRGYKS-
L---AGCLGH--A-PLVLPL-----------------LFFTLFTGL--LVA--ILVQVSK
NPSSQRLDQ----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------K-----QD
EI--SQDLSQLK------------------------------------------------
AAVERLC--RPCPWE-----WTFFQG-NCYFISNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFAWMGLS--D--LNHEGTWQWVD-DSPLS------TSFKQY----WNRGEPNN----
I------GEEDCVEFNG--NGWNDDKCSA-AKF--WICKKSAAS-CSRDEGQLLSS---A
S----AS---------------------PI-AH-------AA-----------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------PSTHS-PP-LK-RCC-----
--------RLG-T-QFALFVL----------------LTGALWAGL--MTL--STLAPKQ
N--------------KT------MILWQKPLG---VSLVSKDLQKYQSDQM---------
--AQKLQ-AAHLEQNVQALQ----------------------------------------
----------------------------------AEQKQMKSQGETEGHCLGGAGVKRGR
LEG-------GPNRRTLSTD-------------PVPPPHPRPPGLNERRTVSDLLEKLQE
EV--AKLWVKIRMA----------------------------------------------
--NGSTC--NTCPEG-----WLNFQQ-KCYYFGEG-TKRWLQARFACSDLEGRLVSIHSQ
EE-----------------------------------------------QDFLSKH-V--
SK-DAWIGLQ--D--LDVEGEFVWMD-GSPVS---------YSN----WLQGEPNNA---
-----G-SDEDCVMMRG-SGHWNDAFCRS-QLD-TWVCERLATC-GPPALPTSGTP---T
PRHTP------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------MA---SEAARDSGSERAGPRT-MIPEG----PEPGEFFD-LP-RKRRC------
--------RRG-L-QLALLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------LKSFKRLEVTAAQN------VSRFSKELQRHHSEQM---------
--AQKTQ-AALMSQTVQELR----------------------------------------
----------------------------------AQQQQMKSQ-----------------
------DSELSWNLDRLQEDMG------S-----IKSQ-----NLNQRRSALDSLGRLKE
EV--AKLWMEIQAS----------------------------------------------
--RGSDC--STCPEQ-----WVNFQQ-KCYYFGEG-AKQWVQARFTCDDLEGRLVSIHSQ
EE-----------------------------------------------QDFLTKH-A--
NKEGSWIGLR--D--LDVEGEFIWMD-GSPVD---------YSN----WQSGEPNNA---
-------QGEDCVMMQG-SGKWNDAFCRS-WLD-AWVCEQLATC-GS-PTPSDATD---D
SRVSGLGSGSA---------------HSP------------------------

------------------------------------------------------------
------------------------------------------MRDAEEAR----------
TQPLGPQDE----------------EE-PTSGGTGYFIKGFGFQP--------TYCLQN-
M---AGRLGRGSV-APVLQL-----------------LSLALFTVV--LVV--ILVKVSK
------VPS-----------------------------------------YQE-------
--RR--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEK--------Q
KI--DKEMSQLKTGI---------------------------------------------
---AGLC--RPCPWD-----WTLFQR-NCYFFSQS-KRNWADSVIACQDMGAQLVVIKSV
EE-----------------------------------------------QNFLQL--NAK
NKGPTWMGLS--D--LKKEGVWQWVD-GSHLW------FSLSNN----WLPGEPNN----
D------GDEDCAEFRG--DGWNDGKCRV-EKF--WICKEPAAS-CSSP-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------TQGLAEASRDREDIRT
EL--FRMIESIQSGN---------------------------------------------
----ASC--EQCPTS-----WLPFQG-SCYLFSRE-WATWDEAQKHCLEAGGHLVIIGGM
NE-----------------------------------------------QSFLVQH-I-G
-DRGHWLGL-RAVRQRSRIQSYQWVD-GVPLS---------FSH----WNRGEPSDS---
------QGREDCIMMLNTG-LWNDAPCTL--RD-NWICEKRRTC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTGTR----------
MQQLGSVED----------------EE-WMVSDTKCSSKISRLRP--------NSGIKS-
L---AGRLGRDQI-PWVLQL-----------------LSFLFLAGL--LLI--ILVQVSK
------TPN-----------------------------------------TQG-------
--QEESK-YEDIYQELTQLTNK----ILSKIPTSKGQNESMQ-EISAQLTQ-----LKTE
LH-SRIPISQGWNESMK-EISEQV----TQLKTELLSR-----------------IPS--
---------------------F------------------------QVQNDSK-----QE
KI--YQQVVQMKAEL---------------------------------------------
---FRLC--RPCPWD-----WTYLLG-NCYFISKS-QRNWSNAVKACQEVEAQLVIIQSD
EE-----------------------------------------------QTFLRQ--TSK
AKGPTWMGLS--D--LNKEATWLWVD-GSPLS------SRFQKY----WNKGEPNN----
V------GEEDCVEFAG--DGWNDSKCEL-QKF--WICKKPATP-CTESQ----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
AQPLGLFEE----------------EE-LITSGMNFFPRDFGFRQ--------TRGYKS-
L---AGCLGH--A-PLVLLL-----------------LSFTLFTGL--LVA--ILIQVSK
NPSSQRQEQ----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------M-----Q-
ET--SQDLAQLK------------------------------------------------
AAVERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACQEAGAQLVVIKSD
EE-----------------------------------------------QNFLQLQ-SSR
SNRLAWMGLS--D--LHEENTWQWVD-GSPLS------PSLRRY----WNRGEPNN----
I------GEEDCVEFNG--NGWNDDKCSA-AKF--WICKKSAAS-CSRDEGWLPPS---V
S----AP---------------------LT-AH-------AA-----------

------------------------------------------------------------
-------------------------------------------MEMCEAE----DPK---
NPGLAELDE----------------DA-LMPSGWSNFNLRT---Q-SL-RRFPVSWLSR-
---------LG-F-LMMMVFF----------------TLSFIL-----SII--ILSRVFQ
N--------------QS----------QYNLD---YEAIQKKLSQLSAQMK---------
--DDWDL-RTKEKLEVSQFIEQ--------------------------LNN----TLN--
------------L-------------------RAKEKLEVSQLIEQLNKNLN-LRTKEKN
EASQ--------LIDQLNKTLNLRAKEQNE------------------------------
-A--SLLIK------------------------------------------------QLN
KTLSTLC--RPCPYK-----WELYKD-SCYSFSVN-QNSWEEAREVCKIDGSDLVIISSS
EE-----------------------------------------------QKYLKQK-TDL
S-RLWWVGLS--D--KKKEGTWHWVD-GTTLEQ---------SF----WNEGEPNN----
-----A-GDEDCCELTS--KNWNDAPCSK-KNN--WICEKEAFS-CLKS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAEICDPK---------E
P------------------------EE-KTWTGPVLVERDLGLLR--------R---LRN
S---PGCLTWPL--LL-LLLF---------VSLGF----FMLLVTT--LVQ------VSR
IH-QSLQRERETS-------------------R--------R-P----------------
--------------------------T---A---------Q--E--K---I--Q---S--
-S-------L--D----K-F-----------L----------------QQMTWMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--HPCPWH-----WEFFQG-RCYLFSQT-QSDWKSSLSACKDIGAQLVIINST
AE-----------------------------------------------QKFLKSW-YVR
YNKATWIGLS--D--DTNEGSWQWVD-NSPLQ------LSF-------WKEGEPNN----
H------GDEDCAELHN--DGWNDSKCTV-ENA--WICEKPSSP-CPML-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEE-----------SS--YSEFTKFS---R-RRRPCC-----
--------SRG-T-QLALLAL----------------VTTALWAGL--LTL--LLLWHWE
N--------------ARNLKQLEETAALN------VSQVSKDLERQKGDQM---------
--AQKSQ-AAQMMQDMERIQ----------------------------------------
----------------------------------TEQKRMESQESELSWNLDGLRADLSD
LKSR--GEQLGRNRGD----------------SYPPTPDPTTQGLNEMRQALDSLGRLQE
EV--GKLWIELRAA----------------------------------------------
--NGSVC--NTCPEA-----WIYFQK-KCYYFGEG-AKKWIQARYACENLHGRLVSIHSP
EE-----------------------------------------------QDFLTKR-A--
NWRGSWIGLR--D--LDIEGEFIWMD-NQPLD---------YSN----WQPGEPNDA---
-----G-QGENCVMMLG-SGKWNDAFCGS-ELH-GWVCDRLATC----------------
------WEQQG-------------TPETPA-CS-------SIPSSPSPDTDP-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------CLDRKPF-ITVL-KL---------ISIVL-------------------------
------------------------------------------------------------
------------------L--A--A-L-----------------------I---------
---------I-------AVIV--------KGTEFLTSQDYDQQKENIHQKLDQVKAGLK-
------------------------------------------------------------
--------------T---------------------------------------------
---EHLC--RPCPWLLFQGDQSLFQR-NCYFFSIS-KKNWMESVKACKYMGAQLVVIKSN
EE-----------------------------------------------QSFLQGI-SK-
KKGNFWMGLS--Y--NNKESKWQWVD-GSPLQG---RVFNFRTY----WSAGEPKM----
R------GNKDCAIRTD--YGWNALPCSH-ESL--WICMKPALP-CPNRRGRYEES---M
S----SK---------------------PV-S---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MRM-HTH----------------------------------------THL
------IAN-----------------------------------------TQG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQAK-----KE
KV--YKEMSQLKPRI---------------------------------------------
---NHLC--RPCRWD-----WTLFQG-NCYYFSKF-QQNWHDSVTACREVGAQLVVIKSD
EE-----------------------------------------------QSFLQQ--MSK
EKGYAWMGLS--D--LKHEGMWHWLD-GSHLL------FSFMKY----WNKGEPNN----
E------GEEDCAEFRD--DGWNDAPCAV-EKY--WICKKSAMS-CTKN-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------MTVSVSREE--------RAQQMG-
C---LGFLDRGHI-PLVLQL-----------------LLLILFAGL--LVA--IVIQVSK
------IPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------LQWEQTK-----QE
KM--YRDLSQLKSEV---------------------------------------------
---DSLC--RRCPWD-----WTFFSG-NCYFFSKS-QRDWHNSITACQEMGAQLVVVRSH
EE-----------------------------------------------QRFLQQ--TSK
KNGYTWMGLS--D--LNKEGAWYWLD-GSPLS------DSLEKY----WNKGQPNN----
I------GGQDCVEFRN--DGWNDAKCEE-MKL--WICKKSATT-CSDK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------SET-RAQLQ-------T-----ARAE
L-------------------------------------------REAQRKLLQQESAL--
--------------NELRER-----------------------VTRDLAKAGEDREKIRS
EL--FRALEAAKFGN---------------------------------------------
----SSC--KPCPTS-----WLPFEG-SCYLFSVL-RAKWEEAQQNCAGAGAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRLVRKIQRYEWVD-GVRLS---------F------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------FL-----------------LE-----------------RVSS
------IAN-----------------------------------------SRG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQEK-----KE
KI--YHEMSQLKPQI---------------------------------------------
---NRLC--RPCPWD-----WTFFQG-NCYFFSKY-QQNWHESVTACNEVGAQLVVIKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMGLS--D--LKREGEWHWVD-GSHLL------FSFMKY----WNKGEPNN----
E------GEEDCAEFRD--DGWNDVPCTV-NKY--WICKKSAMS-CTKK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHE--Y---AGYWE-PP-RKRCCC-----
-------ARRG-T-QLVLVGL----------------LSTAMWAAM--LTL--LLLWHWE
T--------------EKNLKQLGDIAIQN------VSHVSKDLQRYQSNQL---------
--AQKSQ-AVQMSQSMQELQ----------------------------------------
----------------------------------AEQTQMKAQDSELSQNLNRLQEELNN
VESQ--NSELSQNLNRLQEDLI------N-----VKSQ-----GLNEKRTASDSLEKLQE
EV--AKLWIEMLIS----------------------------------------------
--KGAAC--STCPKN-----WLHFQQ-KCYYFGKG-PKQWIQARFACSDLEGRLVSIHSQ
EE-----------------------------------------------QDFLMKH-I--
SK-DSWIGLR--D--LNVEGQFIWMD-GSPVG---------YSN----WSPGEPNNA---
-----E-QGEDCVLMRE-SGQWNDYSCRS-FLY-AWVCEQLATC-EA-SAPLASVS---P
TGPTPSNEP--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MLAT--LVQ------VSR
IR-AYSQGQTQDQ-------------------Q--------G-S---S--S--L--D---
------------------K--V--A-V---P---------R--E--Q---T--H---S--
-G-------L--E----Q-IQQ---I-----Q----------------QQLTQFNAS---
------------------------------------------------------------
--------------L---------------------------------------------
---AGLC--RPCPWD-----WELFQG-SCYLFSRT-LGSWETSASSCEDLGAHLVIVNSV
SE-----------------------------------------------QQFLKYW-HIR
KNQLTWIGLS--D--HRSEGSWQWVD-DTPLK------LSF-------WKEGEPNN----
E------GDEDCVVMAE--DKWNDSRCTA-NNF--WVCEQPSAP-CPGY-----------
-----------------------------------------------------

----------------------------------------------MAGEPEFHQSKNHE
------------------------------------------------------------
-------------------------EE-VTSGEQGFAEHDPEGLI--------CS--SKS
LQ---GHLTQVPW-LL--LLL---------ISLGL----FLLMLAT--LVQ------VSR
IR-AYSQGQTQDQ-------------------Q--------G-S---S--S--L--D---
------------------K--V--A-V---P---------R--E--Q---T--H---S--
-G-------L--E----Q-IQQ---I-----Q----------------QQLTQFNAS---
------------------------------------------------------------
--------------L---------------------------------------------
---AGLC--RPCPWD-----WELFQG-SCYLFSRT-LGSWETSASSCEDLGAHLVIVNSV
SE-----------------------------------------------QRFMKYW-NVR
KNQRSWIGLS--D--HIHEGSWQWVD-GSALK------FSF-------WKEGEPNN----
D------GDEDCVELFM--DDWNDNKCTE-QNF--WVCEQPSAP-CPHH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKETR----------
AQSLGLLEE----------------EE-L---------RDFGFRQ--------TRGYKS-
L-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--AERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSVTACQEVGAQLVVIKSD
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LYEENTWQWVD-GSSLS------P---------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------------------------MDEA--R---HSPN---
PSEITAL-R----------------AE----LPPQQGNTGQWGQT--S-QDKT--W----
------------K-YLCFFVS----------------LILLLTVII--LSV--ILSEVLK
R--------------T--------------------------------------------
------------------------------------------------------------
----------------------------------------QQVQEKVLQ-----------
----------------------LNE-------KVTQGL----------GDAGHDRDFIRS
EV--FRQMK------------------------------------------------AVL
AGNESSC--EPCPLD-----WKFFQG-SCYFFSLD-NLTWTQANDSCVQKQAHLVIINSR
TE-----------------------------------------------QDFLTST-G--
-QVTSWIGLF--K--EGQKGNHRWMD-GSTPT---------YIN----WDSKELPDN---
-----V-TAPACMMMYN-YGHWRDFSCES-GQF-AFICERRQNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSNWGGSSEE-VP-GGH--------
-WRLWEHWSRRPL-FLALTVL----------------VAIVLWADS--EHP--I------
P---LS-------------------------------AASTERAARLWGPD---------
--ALRTN-ASQQTTVLSALKEE----VGACHSCCSGT-QAKLQ-------T-----TRAE
P-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAKAGRDRENVRT
EL--FRALEAVRFQN---------------------------------------------
----SSC--EPCPQS-----WLPFEG-SCCFFSVP-KTTWAAALSHCAHASAHLVF----
--------------------------------------------------GFLTWN-T-R
-GRRYWLGL-RAVLQLDKVQGYQRVDGGVSLT---------FSH----WNRGEPSDC---
------GRSEDCVMMLPTG-LWNDAPCGS--KL-GWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAEMYEHK---------E
P-----DDS----------------EE-ETFGGQRLAERRPRLLH--------S---LRS
L---PECLTWAPL-LLLLLLF---------VSLGF----FTLQLTT--LVQ------VSR
IR--CLQRDSGDH-------------------E--------N-N---S--L--D--KW--
L-D--T---R--F-R--SL--T--E-V---A---------Q--K--Q---M--Q---S--
-N-------L--E----E-I-----------L----------------QRLTRMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--HPCPQN-----WEFFSG-SCYFFSWT-QSDWRSAFSACLLTGAHLVIINST
EE-----------------------------------------------EKFLNFW-YAR
NNKPTWIGLS--D--HHSEGSWRWVD-DSPVQ------LSF-------WKKGEPNN----
H------GDEDCVELHN--DGWNDGRCVT-ENP--WICEKPSAP-CPDL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAEMYEHK---------E
P-----DDS----------------EE-ETFGGQRLAERHPRPLH--------S---LRS
L---SECLTWGPL-LLLLLLF---------VSLGF----FTLQLTT--LVQ------VSR
IQ--CLQRDSGDR-------------------E--------N-N---S--L--D--KW--
L-D--T---R--F-R--SL--T--E-V---A---------E--K--Q---M--Q---S--
-N-------L--E----K-I-----------L----------------QRLTRMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--HPCPQN-----WEFFDG-SCYFFSWT-QSDWRSAVSACLLIGAHLVIIEST
EE-----------------------------------------------EKFLNFW-YPR
NNKPTWIGLS--D--HHSEGSWRWVD-DSPVQ------LSF-------WKKGEPNN----
H------GDEDCVELHN--DGWNDGRCVT-ENP--WICEKPSVP-CPVL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------RSQ----------------PE-LITSGPKCFTKSFGCQP--------TSTFNS-
G---ACKHGCSTI-PL--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------PT---------------------------------------------
---DRLC--RPCPWD-----WTIFQG-RCYFFSKS-QRDWHESVTACQEAGAQLVIVESA
EE-----------------------------------------------QSFLQQ--TSK
SKGRTWMGLS--D--LNKESEWRWVD-GSPLS------LSFMKY----WNPGEPNS----
S------GEEDCAEFYG--DGWNDSKCHV-HKF--FICERSAAS-CST------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGP--------
-WGRWVHWSRRPL-FLALAVL----------------VTTVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGHD---------
--LLRTN-ASKQTAALGALKEE----VGDCHSCCSGT-QAQLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEAGRGREDVRT
EL--FRALEAVRLQN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQDHCADASAHLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------WGRENCVMMLHTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WRR---WSRRPL-FLALAVL----------------VAIVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLGGQG---------
--LLRTN-ASKQTTMLSALKEE----VGACHSCCSGT-QAKLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEAGRDREKVRT
EL--FRALEAVRFQN---------------------------------------------
----SSC--EPCPQS-----WLPFEG-SCYFFSVP-KTTWAAAQSHCADASAHLVTVGDL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRQLGKVQGYQWVD-GVSPT---------FSN----WNRGEPNDS---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
--------------------------G--A-------REKRRMAEMCDSK---------E
P-----GDP----------------EE-EMFGGQKVTRKYTGLLR--------S---SSS
V---SACLTRAQL-PL-LLLL---------ISLGF----FMLLVAT--LVQ------VSR
IH-QSLQKETRDH-------------------Q--------E-S---P--S--Q--D---
------------------P--V--C-V---S---------Q--E--P---T--R---S--
-D-------L--E----D-I-----------L----------------QQLTWMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--LPCPWK-----WELFQG-RCYFFSQT-QDIWKDAISACQNLRAQLVVINST
EE-----------------------------------------------QKFLKSW-NVR
NNQRTWIGLS--D--HHNEGSWKWVD-SSPLQ------LSF-------WKEGEPNN----
R------GDEDCVELYS--DGWNDNRCNT-ENF--WTCEKPSSP-CPGS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------VRMQPLGP---------------
----PGCLGHGH--TFVLQL-----------------LGLTLFAGL--LVA--LLVQVSK
------VPS-----------------------------------------SQE-------
--QE--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QELAK-----QE
KV--YQELTQLKAGV---------------------------------------------
---DRLC--RPCPWD-----LTFFQG-HCYFFSKS-QRNWHDSATACQEEGAQLVVINSA
EE-----------------------------------------------QSFLQL--TTK
KRGHTWMGLS--D--LNKEATWHWVD-GSPLS------LRFMKY----WNPTEPNN----
L------GQEDCAEFDG--DGWNDAKCDI-SKF--WVCKKSALS-CSHEQ----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------S------------------------------------------------PVC
PPPASSC--QPCPPG-----WRKFED-SCYFFSVT-TLLWQEAKDHCIEQGAHLVIINNQ
QE-----------------------------------------------QNFLTQN-D--
-GKGYWIGLT--D--MDTEGTHQWID-GTDLI---------FT-----------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRG-T-QIMLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------TQHLKQLEERAAQN------VSQVSKNLERQHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNTASDLLERLRE
EV--TKLWMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTISWIGLR--N--LNLKGEFIWVD-GSPVD---------YR-----------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDTTEPR----------
LQQLGTLED----------------EE-SLISSTRYSVVSSGLRP--------DFRIKS-
L---AEYLKHSHK-PLVLQL-----------------LSFLFLAGL--LLI--VLGLVSK
------VPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SQV-----QD
KI--YQELMQLKIDV---------------------------------------------
--HDGLC--QPCPRD-----WTFFHG-NCYFFSKS-QRNWHNSVTACQEVGAQLVIVETD
EE-----------------------------------------------QTFLQQ--TSK
AKGPTWMGLS--D--MHNEATWHWVD-GSTLS------PSFEQY----WNKGEPNN----
V------GDEDCAEFSK--DGWNDLKCDS-LNF--WICKKASTSSCTTK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEENL--Y---SGFSE-LP-RKRCC------
--------GWR-T-QLLLVGL----------------VTASLWAAL--LSL--LLLWHWD
T--------------LQNLKQLEETAAQN------VSQISKDLQRYQHIKM---------
--DQKSQ-AAQILQNMEELQ----------------------------------------
----------------------------------AEQKRMKSQDSELSWNLD--------
---------------GLLADLN------N-----LKSQ-----GLNQRREASDMLERLKE
EV--ARLRIELKLS----------------------------------------------
--QGTTC--KMCPKM-----WVYFQQ-KCYYFGEG-AKKWLHAQYACEAMGGRLVSIHSR
EE-----------------------------------------------QDFLIKR-A--
DWKGSWIGLQ--D--LDREGQFTWMD-GSPVS---------YSN----WYPGEPNNQ---
-----D-QGENCVMMRG-SGQWNDAACQS-RLD-AWVCEQLATC-GL-PATLVPVE---P
LGTAPSPEP--------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
AQPLGLLEE----------------EE-LITSSMNFFPRDFGFRQ--------TRGYKS-
L---AGCLGH--A-PLVLPL-----------------LFFTLFTGL--LVA--ILVQVSK
NPSSQRLDQ----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------K-----QD
EI--SQDLSQLK------------------------------------------------
AAVERLC--RPCPWE-----WTFFQG-NCYFISNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFAWMGLS--D--LNQEDTWQWVD-DSPLS------TSFKQY----WNRGEPNN----
I------GEEDCVEFNG--NGWNDDKCSA-AKF--WICKKSAAS-CSRDEGQLLSS---A
S----AS---------------------PI-AH-------AA-----------

------------------------------------------------------------
------------------------------------------MAGDHEPR---------V
P-----GSP----------------EE-DTLGGQRVTREDTEVPA--------RW--PRS
F---PVSRGPWPL-LL--LLF---------LSLAI---CFLLLVTT--LVQ------VSR
IP-KSPAAEAQDR-------------------Q--------E-S---P--S--L--G---
------------------E--G--S-A---S---------Q--E--Q---V--Q---S--
-G-------L--E----Q-I-----------R----------------QQLGQINASL--
------------------------------------------------------------
------------------------------------------------------------
---ARLC--RPCPWN-----WEPFQG-SCYLFSRT-LGVWEASVSSCRDLGAHLVIINSL
AE-----------------------------------------------QRFLRYW-DVR
KDQRTWIGLS--D--HFREGSWQWVD-GAPLQ------LSF-------WQDGEPNN----
D------GDEDCVELFQ--DTWNDNVCTA-QNF--WICEQPVVP-CTGL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTAPYSRWGGGLQE-AP-GGS--------
-WGR---WGRRLL-IVATSLM----------------IATILWALI--LSI--LFSKA--
---------------------------------------STERRVLLGHQD---------
--LLRTN-ASEQTVVLAGLKR-----SDPCDRCCQGT-QAQLQ-------T-----TRTE
L-------------------------------------------GEARAKLFQQESTL--
--------------KELSER-----------------------VTQGLAEAGRDREGIRT
EL--LRALEAARLRN---------------------------------------------
----SPC--EQCPAS-----WLPFQG-SCYLFSIP-TATWDEAQRNCAGAGAHLVIVNDL
DE-----------------------------------------------QGFLSRN-V-R
-GRGYWLGL-RAVRRAEKVQGYQWVD-GVPLS---------FSQ----WNQGEPNDS---
------QGREDCIMMLDTG-MWNDAPCGDNERD-NWICEKRQIC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSQDVK----------
GPQLSLLEE----------------DQ-MVT------VKGQTFPP--------TSRFSS-
V---SGCLGYRLT-LLILQM-----------------LSFIILTVL--LVA--VLNQVAQ
------APN-----------------------------------------FLA-------
--QN--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QS--------EQ
EL--YQELTQLKSAV---------------------------------------------
---DRLC--RPCPWD-----WTYFQE-DCYFFSKS-KRNWENSIKACLEMGAQLVVIETD
EE-----------------------------------------------QSFLQQ--TLK
NKGQTWIGLS--D--LNEEATWRWVN-GLPLS------QGFKQY----WNKGEPNN----
V------GEEDCVEFIG--DGWNDAKCNN-ANL--WICKKPSST-C--------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAGECEPK---------V
P-----GGP----------------EE-DTFGGQRFAKKDPVVST--------YR--PKC
L---PGSWGRWPL-LL--LLS---------LSLAI---CFLLLVTT--LVQ------VSR
IP-KSPQVEAQDH-------------------Q--------E-N---S--S---------
------------------L--V--A-A---S---------Q--D--Q---V--L---S--
-G-------L--E----Q-I-----------Y----------------QQLSQINTSL--
------------------------------------------------------------
------------------------------------------------------------
---ARLC--RPCPWN-----WEPFQG-NCYLFSRT-LGTWESSVSSCQDMGAHLVIINSI
EE-----------------------------------------------QRFLRYW-NIR
RNQLTWIGLS--D--QKREGSWRWVD-HTPLQ------LSF-------WKEGEPNN----
S------GDEDCVELHE--NTWNDNTCTA-QNF--WICEQPLAP-CPGL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGP--------
-WGRWVHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGHD---------
--LLRTN-----------------------------------------------------
------------------------------------------------------------
-------------------------------------------VTHGLAEAGRDREDVST
EL--YRALEAVRLQN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------WRRENCVMMLHTG-LWNDAPCDS-EKD-GWICEKRRNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MAEN----QYSG--ER-FP-RKRRC------
--------RRG-L-QLALLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------LRNFKQLEVTAAQN------VVGGGDGA--RPSMTL---------
--SLRSP-AALMSQTVQELR----------------------------------------
----------------------------------AQQQQMKSQ-----------------
------DSELSWNLDRLQEDMS------S-----IKSQSQPGRDLNERRSALDSMGRLKE
EV--AKLWMEIQVS----------------------------------------------
--KGSEC--STCPKQ-----WVNFQQ-KCYYFGEG-PKQWVQARFTCNDLEGRLVSIHSQ
EE-----------------------------------------------QDFLTKH-A--
NKEGSWIGLR--D--LDIEGEFTWMD-GSPLD---------YSN----WQSGEPNNA---
-------QGEDCVVMQG-SGQWNDAFCRT-WLD-AWVCEQLATC-GP-PTPSDSTD---D
SP----GSGST---------------HSP------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQLLGLLEE----------------EE-LITSGMNFFPRNFGFRQ--------TRGYKS-
L---AGRLSH--A-PLVLLL-----------------LFFTLFTGL--LVA--ILVQGSK
NPSSQRQEQ----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------K-----QE
EI--FQDLSQLK------------------------------------------------
AAVERLC--RRCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSK
SNPLAWMGLS--D--LNQEGTWQWVD-GSPLS------SSFKQY----WNRGEPNN----
I------REEDCVEFNG--NGWNDDKCSV-AKF--WICKMSAAS-CSRDEGRLLPS---A
S----VS---------------------PT-AH-------AA-----------

------------------------------------------------------------
-----------------------------------------------MPR----------
A------------------------GHLLTMDTAGYSKWDNKLEE-VP-GGH--------
-WGH---WGQRSL-LLAFGLV----------------VVTVLWALV--LSI--LFSKA--
---------------------------------------STERGALLGHQD---------
--LLRTN-ASKQTATLKVLKEE----VRACNSCCLGV-QAQLQ-------T-----VHTQ
L-------------------------------------------GEAKAKLLEQESAL--
--------------KELSER-----------------------VTQGLAEAGRDRENIRS
EL--FRELERVRFQN---------------------------------------------
----SSC--EQCPKS-----WLPFQG-SCYFFSAQ-GATWVEAQSHCEGAGAHLVIVGGL
EEQVRSAGSLMEMGG---GGVAGVYLRWVAGEVMGTGRDRFIYL---PAQGFLSRN-T-A
-GRGYWLGL-RAVRRARKIQSYQWVD-GVPLS---------FSH----WNLGEPNDS---
------LGREDCIMMLRTG-MWNDAPCNS-KDD-SWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEMG----------
KKQLGPLDE----------------DQ-MIASPTRYSIKGFGFQP--------NSGFGS-
F---TGHLGLGHV-PLALQV-----------------FFLVVFSVL--LLV--VLVKVFK
------IPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S------------------------PGQEQSS-----QE
KV--YQELTQLKAGV---------------------------------------------
---DRLC--RRCPWD-----WTPFQE-SCYFFSVS-QKTWNDSATACQNVGAQLVVIKSD
EE-----------------------------------------------QKFLQQ--TSK
KRGYTWMGLI--D--MHKESTWHWVN-GSPLT------LSFMKY----WNEGEPNN----
V------GDEDCAEFRG--DGWNDTKCDN-KKF--WICKKPKTS-CPSE-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEENE--Y---SGYWE-PP-RRRCCC-----
-------ARRG-T-QLVLVGL----------------LTTVMWAGL--LAL--LLLWHWE
T--------------EKSLKQLGDAAIQN------VSHVTKDLQNYQSNQL---------
--AQKSQ-ALQMSQNLEELQ----------------------------------------
----------------------------------AEQKQMKSQDSQLSQNLNELQEDLIN
VKSQ--NSELSQNLNTLQEDLV------N-----VKSQ-----GLNEKRAASDSLEKLQE
EV--AKLWIEILMS----------------------------------------------
--KGTAC--NVCPKD-----WLHFQQ-KCYYFGEG-SKQWIQAKFTCSDLEGRLVSIHSQ
KE-----------------------------------------------QDFLMQH-I--
NKKESWIGLQ--D--LNMEGEFVWPD-GSPVG---------YSN----WSPGEPNNG---
-----G-QGEDCVMMRG-SGQWNDAFCRS-YLD-AWVCEQLATC-DL-SAPLASVT---P
TGPTPKNEP--------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MELNE--Y---SGYWE-PP-RKRCCC-----
-------ARTG-T-QLILLGL----------------VTAAMWAGL--LTL--LLLWHWD
T--------------EKNLKHLEDAAVRN------VSHISKDLQRYQREQM---------
--NQQSQ-AAQMSKNMQELG----------------------------------------
----------------------------------AEQKQMKSQDSQLSKNMNRLQ-----
------------------EDLN------N-----IRSR-----NLNEKRTASDSLERLQE
EV--SKLWISVQMS----------------------------------------------
--KGSAC--NTCPKN-----WLNFQQ-KCYYFGKG-SKQWIQAKFTCSNLKGQLVSIHSQ
EE-----------------------------------------------QDFLTKH-I--
KE-DSWIGLR--D--LFTEGEFVWMD-DSPVG---------YSN----WNPGEPNNG---
-----G-QGEDCVMMWG-SGQWNDAFCRS-YLE-SWVCEQLATC-EP-SAPLASMS---P
LSSAEPAS---------------------------------------------

----------------------------------------------MAGEPEFHQPKNHX
------------------------------------------------------------
--------E----------------EE-VTSGDQGFAEHDPEGLI--------CS--SKS
LQ---GHLTQVPW-LL--LLL---------ISLGL----FLLMLAT--LAQ------VSR
IR-AYSQGQTQDQ-------------------Q--------G-S---S--S--L--D---
------------------K--V--A-V---P---------W--E--Q---T--H---S--
-S-------L--E----Q-IQQ---I-----Q----------------QQLTQFXASLG-
--------------------PR------------------------QKGEEKP-----AT
EL--------SVCSV---------------------------------------------
---AGLC--RPCPWD-----WELFQG-SCYLFSRT-LGSWETSASSCKDLGAHLVIVNSV
SE-----------------------------------------------QQFLKYW-DIR
KNQLTWIGLS--D--HRSEGSWQWVD-DTPLK------LSF-------WKEGEPNN----
E------GDEDCVVMAE--DKWNDSRCTA-NNF--WVCEQPSAP-CPRH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MLAT--LAQ------VSR
IR-AYSQGQTQDQ-------------------Q--------G-S---S--S--L--D---
------------------K--V--A-V---P---------W--E--Q---T--H---S--
-S-------L--E----Q-IQQ---I-----Q----------------QQLTQFXAS---
------------------------------------------------------------
--------------L---------------------------------------------
---AGLC--RPCPWD-----WELFQG-SCYLFSRT-LGSWETSASSCKDLGAHLVIVNSV
SE-----------------------------------------------QQFLKYW-DIR
KNQLTWIGLS--D--HRSEGSWQWVD-DTPLK------LSF-------WKEGEPNN----
E------GDEDCVVMAE--DKWNDSRCTA-NNF--WVCEQPSAP-CPRH-----------
-----------------------------------------------------

------------------------------------------------------------
---------------------------------------------MCDLV----APK---
SPEMSGLDE----------------EE-LMPSGWSPFDLGTQRSQ-SP-RSFPAPWLRR-
---------LG-F-PLLLAFF----------------VLSFIL-----SII--TLTQVFQ
N--------------QR----------QYNSE---QEVVQEKLKNLSDKLK---------
--GDQDL-KAKDQPEASLFIQQ--------------------------LNK----TLN--
------------L-------------------RAKDQLEASQLIEQLNKTLN-LRAKDQL
EASQ--------LIEQLNKTLTLRAKDQLEASQFIEELNKASQFIEELNKASQVIEQL-S
KA--SQFIE------------------------------------------------QLN
KTLSTLC--RPCPYE-----WKFYKD-SCYYFSVT-RKPWEASQNTCEADGSNLGIISSS
EE-----------------------------------------------QNYLKKN-AAS
N-HQLWVGLS--D--KKKEGYWHWVD-GTALGQVEHLKAAVHSF----WNEGEPNN----
-----A-GDEDCCELIP--NGWNDASCSK-ENY--WICEKKASP-CPML-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDAGGYSKLGSAIEE-VP-RGQ--------
-LGRWEYYKQRLS-FLVLALL----------------VATVLWTLI--LST--LLSKA--
---------------------------------------SSERRALLSHQD---------
--QLKTN-VSEQKMMLSALKED----VGACGNCCSGM-KAQLQ-------T-----TLAE
F-------------------------------------------KNTQTKLMEQESAL--
--------------KELQER-----------------------VTQSLAKAARDREDIRS
EL--FQALEAVKQQN---------------------------------------------
----KSC--EKCPTS-----WLHFQG-SCYYFSET-QAIWNTAQSFCSVHGAHLVIVKDL
DE-----------------------------------------------QSFLSQR-T-R
-GRGYWLGL-RTVRHLGKIQGYQWVD-GVSLT---------FSH----WNSGEPNDS---
------RGREDCVMMLHSG-LWNDAPCSN-EKD-GWICEKRSSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MRM-HTRLQF-----------------LK----R-------------VSN
------VAY-----------------------------------------SHG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQAK-----KE
KV--YKEMTQLKSQI---------------------------------------------
---NRLC--RPCPWD-----WTVFQG-NCYFFSKF-QQNWNDSVNACRKLDAQLVVIKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMGLS--D--LKHEGRWHWVD-GSHLL------FSFMKY----WNKGEPNN----
E------WEEDCAEFRG--DGWNDAPCTI-KKY--WICKKSAMS-CTEK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--GCWKQRSQRSC-FLALVVL----------------VGIILWALI--LSI--LLSSG--
---------------------------------------RGHVACVLAELV---------
--LLNTT-AKRQTGALETLKEE----VRACSSCCDRGLGLGLK-------C-----SCWP
L-------------------------------------------REKRAELTQQESAL--
--------------EELCQH-----------------------MTQGLAE-GRNRENVRH
EL--FRVLEAVKLQS---------------------------------------------
----SSC--NLCPSL-----WLSFEG-SCYYFLVS-KATWTEAQRHYANAGTHLAIVRGI
DE-----------------------------------------------QIFLTQN-T-H
-GQGYWLGL-RAVGHQSKIQGYRWVD-GVPLS---------FSH----WNHGEPSDS---
------WGLEDCVMLLYVGMIWCSCHCCL-AGP-GWIRNRQLGC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MNPQS--Q---GEGRE-RP-RKRCC------
--------RQG-T-QLVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------LRSLKQLEETAAQN------VSQVSKNFLRHQSDQT---------
--AEQSQ-AAQMLQSLEELR----------------------------------------
----------------------------------AAQKQMKSQDSELSWILD--------
---------------GLQADLN------T-----LKSQ-----NLNERRRTSDFLEGLEE
EV--AKLWMELRVS----------------------------------------------
--GGSVC--NTCPGN-----WVNFQR-KCYYFGEG-AKQWIQARYACSDVGGRLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SKKGSWIGLR--D--LDVEGEFIWMD-GSPVD---------YSN----WLPGEPNNH---
-----G-QGEDCVMMQG-SGHWNDILCRS-KLD-AWVCDRLATC-TP-STASASSC---L
PDPSVSLPLFT---------------F--------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------RVQQMG-
C---LGFLDRGHI-SLVLQL-----------------LLLILFAGL--LAA--IIIQVSK
------IPS-----------------------------------------SE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------MQLEETK-----QE
KM--YRDLSQLKSEV---------------------------------------------
---DSLC--RHCPWD-----WTFFNG-NCYFFSKS-KRNWHDSITACQEVGAQLVIVKSH
EE-----------------------------------------------QSFLQQ--TSK
KNGYTWMGLS--D--LNKEGAWYWLD-DSPLS------DRLGKY----WNRGQPNN----
I------GGQDCVEFRD--EGWNDAKCDE-MKL--WICKKSATT-CSSKW----------
-----------------------------------------------------

----------------------------------------------MAGKPELHQPNNHE
------------------------------------------------------------
--------E----------------EV-------TLEDHDPEGLI--------CS--SKS
LQ---GHLTRAPW-LL--PLL---------ISLGL----FLLMLAT--LVQ------ISR
IC-ANPQGQTQDQ-------------------K--------G-S---S--S--F--G---
------------------K--V--A-V---P---------Q--E--Q---T--Y---T--
-G-------L--E----Q-IQQ---I-----Q----------------QQLTQFNAS---
------------------------------------------------------------
--------------L---------------------------------------------
---AGLC--RPCPWD-----WEFFQG-SCYLFSRT-LASWGASASSCKDLGAHLVIVNSV
AE-----------------------------------------------QQFLKYW-HIR
QSQLTWIGLS--D--HQREGSWQWVD-DTPLK------LSF-------WKEGEPNN----
A------GDEDCVVIAE--DKWNDSTCSA-NNF--WVCEQPSTP-CPGHARSALP-----
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------A--------QTQLLD-
P---LGCHLRHPI-PLVLKL-----------------LLLTVFAGI--LVA--ILVQASS
------VPS-----------------------------------------RQ--------
------------------------------------------------------------
------------------------------------------------------------
---------------------D------------------------YEQDQSQ-----QK
QA--YQELVQMKDTI---------------------------------------------
---NNLC--RRCSWD-----WTFFQG-KCYFLSKS-QRNWHDAITACKEEGAELVIVESA
EE-----------------------------------------------QSFLQQ--ISK
SKGRTWIGLS--D--LNKEGVWHWVD-GSPLS------N---------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------MLGRG-------IHLGLWSQPAQAL----------
SWCSACSEE----------------EE-LITSGIRHSPKDFGFRQ--------FHSLRS-
F---TGCLGRSHA-LLLLQL-----------------ISLTLFTVF--LVA--ILIQVSK
------DPS-----------------------------------------SEG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------LEHSK-----QE
EI--YQELTHLKAGV---------------------------------------------
---ARLC--RPCPWE-----WTFFQG-NCYFFSNT-QRNWHDSIAACQEVGAQLVVIKTA
EE-----------------------------------------------QNFLQVK-TSK
SNRFTWMGLS--D--LKHEGTWHWLD-GSYLL------LSFMKY----WNKGEPNS----
S------GEEDCAEFRG--EGWNDSKCDD-NKF--WICKKTAAS-CSNN-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTVRYSQWESSPEE-VPGGGP--------
-WGRWEYFRPRVC-LLALAVL----------------AVTVLWALI--LSI--LLSKA--
---------------------------------------STDRGALLDRQD---------
--LLRTN-ASEQTVVLGALKRE----VGACRSCCNAT-KATLL-------E-----AVAD
L-------------------------------------------RKAEATLLEQKSAL--
--------------EQLRQR-----------------------VTQDLATAGRDRENIRN
EL--FRELENARLQN---------------------------------------------
----SSC--EQCPTS-----WLPFRG-SCYYFSEP-QATWPEAERNCLGNDAHLVIIGDL
DE-----------------------------------------------QGFVTRH-T-R
-DRGYWLGPYWGVRSAGRIQSYQWVD-GVSLG---------FSH----WNLGEPNDS---
------RGQEDCVMLLHTG-LWNDAPCSS-ELD-GWICEKRRRC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTVTFSQWDSSLVA-VP-TGH--------
-WGRR------VF-FLALAVL----------------VVTVLWVLI--LSI--LMSKA--
---------------------------------------STESRVLTGHQD---------
--LLRTN-ASEQTVALGALKGE----VGAYENCL--------------------------
------------------------------------------------------------
--------------------------------------------TQDLATASRDRENIRN
EL--FRALEAAKLEN---------------------------------------------
----SSC--EQCPAS-----WLPFRG-FCYYFSEA-QASWSEAQQNCAGNAAHLVIIGDL
DE-----------------------------------------------QSFLIRH-T-R
-GRGYWLGL-RAVRRAGRIQGYQWVD-GVQIS---------FSH----WNTGEPNDS---
------WGREDCVMMLHSG-LWNDAPCGS-ERD-GWICEKRRSC-E--------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEE-----------SS--YSEFTKFS---R-RRRPCC-----
--------CRG-T-QLALLAL----------------VTTALWAGL--LTL--LLLWHWE
S--------------ARNLKQLEETAAQN------VSQVSKDLERHKGDQM---------
--AQKSQ-AAQMMQDMERIQ----------------------------------------
----------------------------------TEQKRMESQESELSWNLDGLRADLSD
LKSR--GEWLGRNRGV----------------GGKETPDPTTQGLNEMRQALDSLGRLQE
EV--GKLWIELRAS----------------------------------------------
--NGSVC--DTCPEA-----WIYFQK-KCYYFGEG-AKKWIQARYACEDLDGRLVSIHSP
EE-----------------------------------------------QDFLTKR-A--
SWRGSWIGLR--D--LDIEGEFIWMD-NQPLD---------YSN----WQPGEPNDG---
-----G-QGENCVMMLG-SGKWNDAFCGS-DLH-GWVCDRLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RR-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWYWD
T--------------TQSLKQLEERAARN------VSQVSKNLESHHGDQM---------
--AQKSQ-STQISQELEELR----------------------------------------
----------------------------------AEQQRLKSQDLELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNEASDLLERLRE
EV--TKLRMELQVS----------------------------------------------
--SGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWVHARYACDDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTGSWIGLR--N--LDLKGEFIWVD-GSHVD---------YSN----WAPGEPTSR---
-----S-QGKDCVMMRG-SGRWNDAFCHR-KLG-AWVCDRLATC-TP-PASEGSAE---S
M--GPDSRPGP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGHRVHWSGRPL-FLALAVL----------------VVTVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCRSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELREH-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--CSVHSDE----------------EE-LITSGTRYSLKSFSYRL--------MSTFSC-
L---AEWTNPHRY-LVDSEA-----------------QGL----VI--IIF--FLGTVSK
------VPS-----------------------------------------NE--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------QEEEKSN-----QE
KI--YQELNQFKTGF---------------------------------------------
---DRLC--RPCPWD-----WTFFQG-KCYFFSKS-KRNWHESITACQEAGAQLVIVEND
EE-----------------------------------------------QSFLQQ--TSK
KKGFAWMGLS--D--LNKESTWRWVD-DSPLA------FSLMQY----WNKGQPNN----
N------NEQDCVEFRG--DGWNDARCDI-KKF--WICKKSVTP-CSNK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTSGYSKWGGEPEE-VP-GGY--------
-WGRWEQRSRRSC-FLALALL----------------AAAVLWAVI--LSV--LLSKA--
---------------------------------------STERAALLGGQH---------
--LLKTN-ASKQTAALGTLKEE----VAACHSCCSGT-QAQLQ-------A-----TRVE
L-------------------------------------------GETQAKLSQQETAL--
--------------KELGER-----------------------VTQGLAEAGRDREDVRN
EL--FRALEAARHQN---------------------------------------------
----SSC--NPCPQS-----WLPFEG-SCYYFSVP-QATWVEAQRHCAGAGGYLVIVGGL
DE-----------------------------------------------QSFLTQN-T-R
-GRGYWLGL-RAVRHQSKIQGYQWVDGG-PLS---------FSH----WNQGEPNDS---
------WGRENCVMMLHTG-MWNDAPCDN-ERD-GWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------TQTVKQLEERAARN------VSQVSKNLERHHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNAASDLLERLRE
EV--MKLRMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDVEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SRTGSWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPTSQ---
-----S-QGKDCVMMRG-SSHWNNAFCDR-KLG-AWVCDRLATC-AP-PASEGSTE---S
L--GPESRSGP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQLLGLLEE----------------EE-LITSGMNFFPRNFGFRQ--------TRGYKS-
L---AGRLSH--A-PLVLLL-----------------LFFTLFTGL--LVA--ILVQGSK
NPSSQRQEQ----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------K-----QE
EI--FQDLSQLK------------------------------------------------
AAVERLC--RRCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNQEGTWQWVD-GSPLS------SSFKQY----WNRGEPNN----
I------RKEDCVEFNG--NGWNDDKCSA-AKF--WICKMSAAS-CSRDEGQLLPS---A
S----VS---------------------PT-AH-------AA-----------

------------------------------------------------------------
------------------------------------------MSDSTEAR----------
MQPLSSMED----------------DE-LMVSSSRYSIKSSRLRP--------NSGIKS-
L---AGYLGHSQV-PLVLQL-----------------LSFLFLAGL--LLI--ILFQVSK
------TPN-----------------------------------------TQG-------
--QK--E-REKILQELTQMTDE----LMSRIPISPGQNESMQEKVTEQLMQ-----LKTE
LL-SRIPIFQGQNESMQE-ISEQL----TQLKAELLSK-----------------IPS--
---------------------F------------------------PVEDDSK-----QE
KI--YQELVQMKTEL---------------------------------------------
---LRLC--RLCPWD-----WTFLLG-NCYFFSKS-QRNWNDAVSACKEVKAQLVIINSD
EE-----------------------------------------------QIFLQQ--TSK
AKGATWMGLS--D--LNKEATWLWVD-GSTLS------SRFQKY----WNKGEPNN----
I------GEEDCVEFAG--DGWNDSRCEL-KKF--WICKKAATP-CTEG-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSMESK----------
TQQVVIPED----------------EE-CLMSGTRYSDISSRLQT--------KFGIKS-
L---AEYTKQSRN-PLVLQL-----------------LSFLFLAGL--LLI--ILILVSK
------VPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SEV-----QN
KI--YQELMQLKAEV---------------------------------------------
--HDGLC--QPCARD-----WTFFNG-SCYFFSKS-QRNWHNSTTACQELGAQLVIIETD
EE-----------------------------------------------QTFLQQ--TSK
ARGPTWMGLS--D--MHNEATWHWVD-GSPLS------PSFTRY----WNRGEPNN----
V------GDEDCAEFSG--DGWNDLSCDK-LLF--WICKKVSTSSCTTK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------RGLGFRQ--------TRGYKS-
L---AGCLGH--G-VLVLQL-----------------LSFTLLAGL--FVQ------VSK
VPSSISQEQSRQDSIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVSEL-------
--PEKSK-QQEIYQELTQLKAA----VSELPEK------SKLQEIYQELTR-----LKAA
VGE-------LPEKCKQQEIYQEL----TRLKAAVDELPEKSKLQEIYQELTRLKAAVGE
LPEKSRLQEIYQELTQLKAAVG------------------------DLPEQSK-----QE
EI--FQDLSQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFISNS-QRNWHDSITACQEVGAQLVIIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFAWMGLS--D--LNQEGTWQWMD-GSPLS------SSFEQY----WNRGEPNN----
I------GEEDCVEFNG--NGWNDDKCSA-AKF--WICKKSAAS-CSRDEGRLLPS---A
S----IS---------------------PT-AH-------AV-----------

----------------------------------------------MAGERETQQPKNHG
EAGHLWVLSGELGPGSRVICAWPPAWG--E-------GGGRALEVSCCVL---------S
------HSE----------------EE-VTFGGQGCAENDPEGLT--------CR--SKS
M---PECLARMPW-LL--LLL---------ISLGL----FVLMLAI--LVQ------VSR
VH-ASPQGQTPGQ-------------------Q--------G-S---S--S--L--V---
------------------------A-V---P---------H--A--Q---T--H------
-S-------L--E----Q-I-----------Q----------------QQLTQINAS---
--------------------PR------------------------QRGEENP-----GP
EV--M-------------------------------------------------------
---AGLC--RPCPWD-----WELFQG-SCYLFSRT-LSSWEASATSCQDLGAHLVIINSV
EE-----------------------------------------------QRFMEYW-NVR
KKQRSWIGLS--D--LRHEGSWQWVD-DTPLQ------LSF-------WKQGEPNN----
D------EDEDCVELFT--DEWNDNKCTE-QNF--WVCEQPSAP-CPHH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------LNVSKEPR----------
AHQLQLLDT----------------GK-LGQV---------SILP---------------
----TGHL--CHA-SLVLLF-----------------LSFMVLAGL--LVT--ILIVGLA
FWL-WKEPEV---ASSRKAVGLKVAVGSLG-ASKGLSSVGKELTQLKPAMGEG-------
--PERSR-QEETYKELAQLKAA----VDAFPQL-------SRQEIYKELTQ-----LKAA
VG--TF-----PQRSRQEEMYKEL----TQLKTGIR------------------------
----------------------------------------------ECPAQSR-----QE
EI--YQQVTQLNAAVG--ECPDTRSPMA------------GE----------FPCAVTLL
GSHCHLC--CRCPWD-----WTFFQG-NCYFFSTI-QRNRHNSMTACQEVGAQLVMIKST
EE-----------------------------------------------QDFLRLQ-VST
KERHTWIGLS--D--LTHEGTWQWVD-GSPLP------SSFTKY----WNNGEPNN----
I------GEEDCVEFKG--KGWNDHKCNV-LNF--WICKKSAAS-CPRQDSFSPSP---N
T----NK---------------------PP-GI--------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEESR--Y---SGFSE-SP-RKRCC------
--------GWG-T-RLVLLGL----------------ATAALWAGL--LSL--LLMWHWD
T--------------LRSQRLLEEATARN------VSRLSKDLQRRQHDQV---------
--AQESQ-AAQMLQHMEELR----------------------------------------
----------------------------------AEQKRLKSQESELSGHLD--------
---------------TLLADLN------N-----LRAQ-----ALNAGRAASDSAARLQE
EV--ARLRVELQLS----------------------------------------------
--KGVTC--NTCPEE-----WVHFQQ-KCYYFGEG-AKKWLHAQYACEDVGGRLASIHGA
EE-----------------------------------------------QDFLSKR-A--
SWKGSWIGLQ--D--LDREGQFTWMD-GTPMD---------YSN----WSPGEPNNQ---
-----A-QGEDCVMMRG-SGQWNDAACHS-KLD-AWVCDRLATC-GP-PTTSTPEG---P
PGTTPSL----------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQQLGLLEE----------------DP--TTSGIRLFPRDFQFQQ--------IHGHKS-
S---TGCLGH--G-ALVLQL-----------------LSFMLLAGV--LVA--ILVQVSK
VPSSLSQEQSEQDAIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSK-LQEIYQELTRLKAA----VGELPEK------SKLQEIYQELTR-----LKAA
VGE-------LPEKSKLQEIYQEL----TRLK----------------------------
------------------AAVG------------------------ELPEKSK-----LQ
EI--YQELTELKAAVG--ELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLK
TAFERLC--RHCPKD-----WTFFQG-NCYFMSNS-QRNWHDSVTACQEVRAQLVVIKTA
EE-----------------------------------------------QNFLQLQ-TSR
SNRFSWMGLS--D--LNQEGTWQWVD-GSPLS------PSFQRY----WNSGEPNN----
S------GNEDCAEFSG--SGWNDNRCDV-DNY--WICKKPAA--CFRDE----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------LASAC-PG---------S
ELMSAHAEE----------------EQ-LTGSSCRFFARHMGSQK--------TPGLCLW
LWKEPGVTSSRTQ-VGLKAGI---------GSLGFPGVSFLL-AGT-----------VSK
LPSFLGQDEIYEE-----------------------------LS------Q--L------
------------------K--A--A-V---G------------E----------------
---------F-PE---------------------------RSRQEKIYQDMAQLKAAVGE
YTVGTQL----------SRSPG------------------------CRPEL-------SG
SQ--P-WPP---APT---------------------------------------------
---DHLC--CPCPWD-----WTFFQG-NCYFFSNS-QRNWHDSISACQDVGAQLVVIKGD
EE-----------------------------------------------QNFLQLQ-SSW
RNRVSWIGMS--D--MTQEGSWQWVD-GSPLP------PSFTKH----WNSGEPNN----
I------GEEDCVELFS--KGWNDSQCNH-AKF--WICKMSAAS-CPSEQGRVPAS---T
A----AP---------------------TL-SA-------Q------------

--------------------------------------------------M---------
-------------------------------------AGEPEPQQPGSHA---------E
EV----------------------------------TFGGQRFTEKDP-EGLSHSP--TS
L---PEC-LTG-V-PWLLLLL----------------FSLGLFSVL--LLA--TLVQ---
-------------------------------------AGSRIPESPPGETQ---------
--DDRGI-PSLG--EEVPPQ-Q--------------------------IPS----SL---
--------------------------------------------EQIQQQLIQI------
-----------------NASLG-------------KGL--------------G-----PE
S-----------------------------------------------------------
-GAIGLY--CPCPSD-----WELFQG-SRYLFSWTLGS-WQASVSACQDLGAHLVIVNSI
AE-----------------------------------------------QSFLNHCHIRK
NELSS-ISLR--E--DKRGFWLGWLSLMAGVV---------CSF----WKEGEPNND---
-------VDEDCVKLRE--DRWNDSTCTA-QNF--WVCEQPAAP-C--------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGP--------
-WGRWVHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSSA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGDCHSCCSGT-QAQLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------QELRER-----------------------VTQGLAEAGRDREDVRT
EL--FRALEAVRLQN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------WGRENCVMMLHTG-LWNDAPCDS-EKD-GWICEKRRNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LS-RR-RCC-----
--------RRG-T-QIVLLGL----------------LTAALWSGL--LTL--LLLWHWD
T--------------TQSLKQLEERAARN------VSQVSKNLERHHGDQM---------
--AQKSQ-STQISQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDLELSWNLN--------
---------------GLQEDLS------S-----FKSQ-----ELNERNEASDLLERLRK
EV--TKLRMELQVS----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------SN----WAPGEPTSR---
-----S-QGEDCVMMRG-SGHWHDAFCDR-KLG-TWVCDRLATC-TP-PASEGSAE---S
V--GPDSRPGP-------------DGRLPA-PS-------APLRS--------

------------------------------------------------------------
------------------------------------------MAEMCDPK---------E
P-----GDP----------------EE-EMFGGQRTTKKYTGLLR--------S---SRS
L---PGCLTQAHL-PL-LLLL---------ISLGF----FMLLVTT--LVQ------VSR
IR-QSLQKETWDH-------------------Q--------E-N---P--S--Q--V---
------------------------D-V---S---------Q--K--R---T--R---S--
-D-------L--D----E-I-----------L----------------QQLTWMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RPCPWK-----WELFQE-SCYFFSQT-QNTWKESISACQNLRAQLVIINST
EE-----------------------------------------------QKFLKSW-NTR
NNQRTWIGLS--D--HHNEGSWKWVD-NTPLQ------LSF-------WKEGEPNN----
H------GDEDCVELYS--DGWNDNRCST-ENF--WICKKPSSP-CPGP-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------GGAGFRQ--------TRGYKS-
L---AGCLGH--G-PLALQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKVAVSELS-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-QQEIYQELTRLKAA----VGELPEK------SKQQEIYQELTR-----LKAA
VGE-------LPEKSKLQEIYQEL----TRLKAAVGELPEKSKQQEIYQELTRLKAAVGE
LPEKSKQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFISNS-QRNWHNSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNHEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSRDEERLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MHM-HTHLQF-----------------LK-----------------RVSI
------IAS-----------------------------------------SWG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQAK-----KE
KV--YQEMSQLKPQI---------------------------------------------
---NRLC--RPCPWD-----WTFFQG-SCYFFSTF-QQNWHESVTACKEVGAQLVVIKSD
DE-----------------------------------------------QSFLQR--TSK
EKGYAWMGLS--D--LKREGVWHWVD-GSHLL------F---------------------
------------------------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------V-----------------TVSS
------IAN-----------------------------------------SRG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQEK-----KE
KI--YHEMSQLKPQI---------------------------------------------
---NRLC--RPCPWD-----WTFFQG-NCYFFSKY-QQNWHESVTACNEVGAQLVVIKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMGLS--D--LKREGEWHWVD-GSHLL------FSFMKY----WNKGEPNN----
E------GEEDCAEFRD--DGWNDVPCTV-NKY--WICKKSAMS-CTKK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------M-E----------------GK----YPPIQGKPAQRDQR-LP-QDDP--W----
------------K-FFCLAMT----------------LMLLLFDLI--LGV--VLAEVLL
F--------------S--------------------------------------------
------------------------------------------------------------
----------------------------------------NKMQEDLKQ-----------
-----------------------------MDIQFVQGL----------ADAGHERDIVWG
EV--FRQTE------------------------------------------------AVR
AGNESSC--EPCHEN-----WTAFQG-SCYQFSTQ-ELSWFKAKDHCAEKGAHLVIINSQ
AE-----------------------------------------------QKFLSPK-E--
-NNGYWIGLR--K--QYPKGIHKWQD-GSVPT---------FIN----WRNTRSS-----
--------HYDCAFLMG-SGSWSSTTCYA-YWYH-WICEKPQVC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LS-RKKGCC-----
--------RHW-T-QTMLLGL----------------LTAALWAGL--LTL--ILLWHRD
N--------------TQNLKQLEERAARN------VSQVSKYFERYQGDQM---------
--AQKSQ-ATEISQSLEELR----------------------------------------
----------------------------------AEQQRMKY-DSEMYWNLN--------
---------------RLQADLS------S-----FKSQ-----ELNERHAASDSLGRLQE
EV--RKLLMELQVS----------------------------------------------
--RGFVC--NMCPEN-----WVSFQQ-KCYYFGKG-TKQWVHARYACEDMEGQLVSIHSH
EE-----------------------------------------------QDFLIKH-A--
SRTGSWIGLR--N--LDLKGEFIWMD-GTPVD---------YSN----WAPEEPTNR---
-----N-QGEDCVMMRG-SGDWNDIYCDR-KLG-TWVCDRLATC-TL-PAREGSAE---S
--PGPDSEPDQ-------------NGRLPT-PS-------APLHP--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTGGYSKLDTAGEE-VP-RGQ--------
-LGRWEHYKQRLF-FLVLAFL----------------VATVLWALI--LST--LLSKA--
---------------------------------------SSERRTLLSRQD---------
--LLKTN-ASEQKMMLSTLKED----VGACRNCCSGI-KAQLQ-------A-----TLAE
F-------------------------------------------KDAQAKLMEQESTL--
--------------KELQER-----------------------VTQGLAKAGRDREDIRS
EL--LQALEAVKQQN---------------------------------------------
----RSC--EQCPTS-----WLYFQG-SCYYFSET-QAIWSTAQSYCSVHGAHLAIVKGP
DE-----------------------------------------------QGFLSQH-T-H
-GRGYWLGL-KAVRHLGKIRGYQWVD-GVSLT---------FSH----WNSGEPNDS---
------RGHEDCIMMLHSG-LWNDAPCTN-ERD-GWICEKRSSC-CP-------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDIDGYSKWDGRLEE-VP-GGH--------
-LGR---WGRRPL-FLLFALV----------------VITVLWALI--LSV--LFSKA--
---------------------------------------STERGALLDLQD---------
--GLSAN-ASKQTAVLGILEEE----VRACNSCCLRT-QAQLQ-------T-----VSKE
L-------------------------------------------TEARSKLLQQESAL--
--------------KELSER-----------------------VTQNLAEAGRDRENIRT
EL--FRALEQARLGN---------------------------------------------
----SSC--KECPES-----WLPFQG-SCYFFSTL-RATWVEAQQHCERSGAHLVIVGGL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRKVRRIQGYQWVD-GVALS---------FSH----WNRGEPNDS---
------MGREDCIMMLRTG-MWNDAPCDN-END-NWICEKRLSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MNSSNYQKWEEDKDN-LVLDKSQQVESSQ-
STGSWRKLLPRDPPSKSAFLM----------------LSITLLLLI--LLIV-TLVKG--
---------------------------------------SKTSQELNQLKQ---------
--EMRTN-ASSQTKDVKQLRED----IVAAKRNGSTL-WASLG-------S-----SEKK
L-------------------------------------------SETHARLLNLESKH--
--------------DELSTQ-----------------------MTQALADAGKDRQDIRS
EM--FRAVAAVKTGN---------------------------------------------
----SSC--SPCPDS-----WLAFEG-SCYFFSTT-KAHWDKSQQNCAKEQAHLVIVNNL
EE-----------------------------------------------QTFLTQN-T-K
-GLGYWIGL-TATRSRGRVNGYIWID-GTKLT---------FSY----WNEGEPNDS---
------RKNENCIMILYSG-RWNDAPCAN-LND-YWICEKRQQC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTESK----------
TQQVGIPED----------------EE-CLMSGTRYSDISSRLRT--------KFGIKS-
L---AEYTKQSRN-PLVLQL-----------------FSFLFLAGL--LLI--ILILVSK
------VPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SEV-----QN
KI--YQELMQLKAEV---------------------------------------------
--HDGLC--QPCPRD-----WTFFNG-SCYFFSKS-QRNWNNSITACQELGAQLVIIETD
EE-----------------------------------------------QTFLQQ--TSK
ARGPTWMGLS--D--MHNEATWHWVD-GSPLS------PSFTQY----WNRGEPNN----
V------GDEDCAEFSG--NGWNDLRCDN-SLF--WICKKVSTSSCTTK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEERS--YVEFEDPP------RKRCC-----
--------RRG-T-QLILLGL----------------VTASIWAVL--LTL--LILWRWD
T--------------AQSLKQLEQSALRN------VSQVSKDLERHKSDQM---------
--AQKTQ-AAQMLKNIENVE----------------------------------------
----------------------------------AEQKGMKFHESELSRYLEGLGADLSN
LKSK---------------------------------------SLNERRADSDSLERLQE
EV--AKLWMELKML----------------------------------------------
--NGSTC--NTCPEK-----WINFQR-KCYYFGDS-AQMWLQAKYTCEDLHGRLVSIHSS
EE-----------------------------------------------QEFLRRH-I--
HRKDSWIGLQ--D--LDIEGEFIWSD-GSPMD---------YSN----WRPGEPNDQ---
-----D-QGENCVMILGSSGQWNDAFCRS-QLE-GWVCEQLATC-SLNS-----------
----------------------------PT-CH-------ILPTGRTPAGQA-

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------R--------
-WGRWENFRQRSF-FLALALL----------------VATVLWAFI--LSI--LTSKA--
---------------------------------------STERTALLSHQD---------
--VLRMN-VSEQSVMLDALKEE----VGTCKNCCSWT-EAELH-------T-----ALSE
L-------------------------------------------RGLHVKLLDLMGNV--
--------------NELQEH-----------------------VAQGLAKADRDREDIRT
KL--FQKLEASKCQN---------------------------------------------
----GSC--DQCPTS-----WLTFQG-SCYYFSEQ-KATWKVAQNHCASQGAHLVVIRDL
EE-----------------------------------------------QDFLNKH-T-R
-GQGYWLGL-RAVRLQGKIQGYKWLD-GVSLT---------FSH----WNTGEPNDS---
------RGQEDCVMMLPSG-LWNDAPCSS-EKD-SWICKKRVNC-YP-------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------MERKEKS--RRDQQGA--TFLSMPR----------
A------------------------GRLLTMDTAGYSKWDSRLEE-VP-GGH--------
-WGR---WGRRLL-FLALVLV----------------AALALWALI--LSI--LFSKA--
---------------------------------------STERGALFGHQD---------
--LLRTN-ASKQKAALGVLNAE----VRACNSCCSGT-QTLLE-------K-----ARAE
L-------------------------------------------GEAQAKLIEQESAL--
--------------KELSDR-----------------------VTQSLAEASRDREDIRS
EL--FRALEAARLGN---------------------------------------------
----SSC--EECPAS-----WLPFQG-SCYLFSIL-RATWEESQRNCAGSGGHLVIVGDL
EE-----------------------------------------------QGFLSRN-T-R
-GRGYWLGL-RAVRRARQIQGYQWVD-GVPLS---------FSH----WNLGEPNDS---
------MGREDCVMMLRTG-MWNDAPCDN-ERD-NWICEKRRSC----------------
-----------------------------------------------------

----------------------------------------------MAGEPEPQRPKNH-
------------------------------------------------------------
--------G----------------EE-ITFGGKGFAESNPQGLI--------PS--CKS
MCQGPLKNEHIPW-LL--LLL---------ISLGL----FVLMLAI--LVQ------VSR
IH-GYPQGQTLDQ-------------------Q--------G-S---S--S--L--D---
------------------------A-V---P---------H--E--Q---T--H---S--
-S-------L--E----Q-I-----------Q----------------HQLTQINASL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--RPCPWY-----WELFQG-SCYLFSRT-LGSWEASASACQALGAHLVIVNSI
EE-----------------------------------------------QRFMKYW-NMR
KNRRSWIGLS--D--HRHEGFWHWVD-DTPLQ------LSF-------WKKGEPNN----
D------EDEDCVELFM--DDWNDNKCTE-ENF--WVCEQPSAP-CPGH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------V--------GEAGAK-
P---LAFLGHGHV-PQLLQL-----------------ILFVLLAAL--LMA--TFIQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---DHLC--RPCPWD-----WISFQG-HCYFLSNS-QRNWHDSVTACQEVEAQLVSIESD
EE-----------------------------------------------QSFLQQ--TSK
KKGYTWMGLS--D--LNQEAAWVWVD-GSPLS------NRLKKY----WNKGQPNN----
N------GGQDCVEFRG--EGWNDSNCDN-KKF--WICKKSLSP-CSHKW----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLDLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKVAVSELS-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-QQEI---------------------------------YEELTR-----LKAA
VGE-------LPEKSKLQEIYQEL----TRLKAAVGELPEKSKQQEIYQELSRLKAAVGD
LPEKSKQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAATV--IVW---------------------------------CDPDRP
PPTERLC--HPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNHEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
V------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSGDEERLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------MQQQDGYL---HWDN---
SVRLSLA-E----------------IQ--------PRRAG-SSLQ-LP-RGWA--T----
------------L-PLYLVLA----------------GTLVLWGSL--LGV--MLAKEPP
N--------------RS----------INESG---ASMVRRDVEELVVAVE---------
--AVKSN-GSRAWTQLSIMQGA--------------------------LRG----RDT--
------------E-------------------LSDV-------RIQLLL-----------
----------------------LEGKHSQLSAQVTQEL----------AQAGKAQEDLRS
EM--FRAVS------------------------------------------------ALQ
RGHTSSC--QPCPID-----WKTFEG-SCYFFSPT-KSSWHSAKSKCLSEGSHLVIINDQ
QE-----------------------------------------------QNFLTQN-T--
NNFGYWIGLS--D--TEVEGKHKWID-GSDIT---------FVY----WNRGEPNDS---
-----Y-GREDCVMMLS-HGHWNDAPCSS-ELD-NWICEKRQQS-C--------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTGGYSKLGSAIEE-VP-QGQ--------
-LGRWEYYKQRLF-FLVLAFL----------------VATVLWVLI--LST--LLSKA--
---------------------------------------SNERRALLSHQD---------
--LLKTN-ASEQNMMLSALKED----VRGCRNCCSGI-KAQLQ-------T-----TLAE
F-------------------------------------------KDTRAKLMEQESAL--
--------------KELQDR-----------------------VTQGLAKAGRDREDIRN
EL--LRALEAVKQQN---------------------------------------------
----RSC--EQCPTS-----WLFFQG-SCYYFSET-QAVWDTAQSYCSAHGAYLVIVKGP
EE-----------------------------------------------QGFLSQH-T-R
-GRGYWLGL-KAVRRLGKIQGYQWVD-GVSLT---------FSN----WNSGEPNDS---
------RGQEDCVMMLHSG-LWNDAPCTN-ERD-GWICEKRSIC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
VQQLGLLEE----------------DP--TTSGIRLFPRDFQFQQ--------IHGHKS-
S---TVPFL---------------------------------------------LGPVSK
VPSSLSQEQSEQDTIYQNLTQLKAAVGELS-EKSKLQEIYQELTQLKAAVGEL-------
--PEKSE-LQEIYQELTQLKAA----LGKLPDQ------SKQQQIYQELTD-----LKTA
FGE-------FLNGLSS-------------------------------------------
----------------------------------------------------------FQ
E---------------------------VHP------------------TWTVKEGPDQP
PPTERLC--RHCPKD-----WTFFQG-NCYFMSNS-QRNWHNSVTACREVRAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-TSR
SNRFSWMGLS--D--LNQEGTWQWVD-GSPLS------PSFQRY----WNSGEPNN----
S------GNEDCAEFSG--SGWNDNRCDI-DNY--WICKKPAV--CFRDE----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGHRVHWSRRPL-FLALAVL----------------VTIVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLGGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCRSCCSGT-QAQLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCANASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKIQGYQWVD-GVSLS---------FSH----WNRGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MTDTKEAR----------
APQLGPLDE----------------EE-LIAVGPRSFLKGFGYQR--------SSGYSH-
C---AGCLGNDSS-RLVLQL-----------------LAIMLFSAL--LVA--ILVQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---DNLC--RPCPWE-----WTFFQG-KCYFFSKS-QRNWHDSGTACEEEGARLVIVESA
DE-----------------------------------------------QSFLQL--TSK
SKGHTWMGLS--D--LNKESTWHWVD-GSPLL------LSFMKY----WNPSEPNN----
L------GEEDCAEFDG--DGWNDARCDI-SKY--FICKQAAAS-CSN------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LS-RKKGCH-----
--------KHW-T-QTVLLGL----------------LTTALWAGL--LTL--LLLWHGD
T--------------TQNLKQLEERAALN------VSQVSKYFERYQGDQM---------
--AQKSQ-ATEISQSLEELR----------------------------------------
----------------------------------AEQQKMKSEDSQLYWNLN--------
---------------KLEDDLS------S-----FKSQ-----ELNQRHAASDLLGRLQE
EV--RKLQMELQVS----------------------------------------------
--RGFVC--NACPEN-----WVSFQQ-KCYYFGKG-TKQWVHARYACEDMEGQLVSIHSH
EE-----------------------------------------------QDFLIKH-A--
SHTGSWIGLR--N--LDLKGEFIWMD-GTPVD---------YSN----WAPEEPTNR---
-----N-QGEDCVMMRG-SGDWNDIYCDR-KLG-AWVCDRLATC-VP-LDREGSAE---F
--LGPDSEPGQ-------------DGRLPI-PS-------ALLHP--------

------------------------------------------------------------
---------------------------------------------MPSGS---IYRKYEE
-SDQETLTVQ---------------EA-DMA---------LGRAG--S-SLQQCG---TG
L---AGESRSV-L-ALYAVHA----------------MSFVLWAIL--LAV--LVAKSSE
M--------------SKEL------------------------EQLRTDQS---------
--LLRGN-GSKAAKQLQMLH----------------------------------------
----------------------------------FNQSAMHSIEAELAIDLKRLQSDQAL
MKKE------------VMEDLA------K-----GK----------------SDRDDIRA
QA--YQILDT------------------------------------------------IQ
KGKNSNC--SICPAN-----WLLYAG-TCYYFSTE-RKHWSYAKQACTDQGGQLIIIDNE
QE-----------------------------------------------QEFLAKN-A--
KGKQYWIGLH--D--INNEGTFIWVD-NNPLS---------YSN----WNRGEPNDY---
-----G-GGEDCVMMFR-DGKWNDMPCAA-SEE-GWICEKKWTC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MRM-HTRLQF-----------------LK----R-------------VSN
------VAY-----------------------------------------SYG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QEQAK-----KE
KV--YKEMTQLKPQI---------------------------------------------
---NRLC--RPCPWD-----WTVFQG-NCYFFSKF-QQNWNDSVNACRKLDAQLVVIKSD
DE-----------------------------------------------QSFLQQ--TSK
EKGYAWMGLS--D--LKHEGRWHWVD-GSHLL------FSFMKY----WNKGEPNN----
E------WEEDCAEFRG--DGWNDAPCTI-KKY--WICKKSAMS-CTEK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GEH--------
-WRRWEHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERSALLGGQD---------
--LLRTN-G-------------------------SGT-QAKLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEAGRDRENVRT
EL--FRALEAVRFQN---------------------------------------------
----SSC--EPCPQW-----WLPFEG-SCYFFSVP-KTTWAAAQSHCADASAHLVIVGDL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRQLGKVQGYQWVD-GVSLT---------FSH----WNRGEPNDS---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-SWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------TQTVKQLEERAARN------VSQVSKNLERHHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNAASDLLERLRE
EV--MKLRMELQVS----------------------------------------------
--NGFVC--NMCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTGSWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPTSQ---
-----S-QGKDCVMMRG-SSHWNNAFCDR-KLG-AWVCDRLATC-AP-PASEGSTE---S
L--GPESRSSP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------LSGDCCVL---------F
H-----YSE----------------EE-VTFEVQKFTESDHEGLI--------CS--SKS
I---PEYLTRVPW-LL--LLL---------ICLSI----FVLMLAT--LVQ------VSR
IR-GCPQRLISDQ-------------------Q--------G-S---S--S--L--V---
------------------------A-V---P---------Q--E--L---T--Q---S--
-I-------L--E----K-V-----------Q----------------QQLNQINVSLG-
--------------------PR------------------------QRGEGNP-----GA
EL--M-WPHCPVCSV---------------------------------------------
---AGLC--RPCPWE-----WELFQG-SCYLFSRT-LGSWEASVTSCQNLGAHLVIVNSF
EE-----------------------------------------------QQFLKYL-HIR
KNELTWIGLS--D--HRHEGSWHWVD-GTPLG------LSF-------WKDGEPNN----
E------GDEDCVELSE--DKWNDKRCAA-KNF--WICEKPSAP-CPGH-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTEAR----------
MQPLSSMED----------------DE-LMVSGSRYSIKSSRLRP--------NSGIKS-
L---AGCSGHSQV-PLVLQL-----------------LSFLFLAGL--LLI--ILFQVPK
------TPN-----------------------------------------TER-------
--QK--E-EEKILQELTQLTDE----LKSRILISQGKNESMQEKITEQMMQ-----LKTE
LL-SRIPIFQGQNESMQEKISEQL----MQLKAELLSK-----------------ISS--
---------------------F------------------------PVEDDSK-----QE
KI--YQQLVQMKTEL---------------------------------------------
---FRLC--RLCPWD-----WTLLLG-NCYFFSKS-QRNWNDAVTACKEVKAQLVIINSD
EE-----------------------------------------------QTFLQL--TSK
AKGPTWMGLS--D--LKKEATWLWVD-GSTLS------TRFQKY----WNRGEPNN----
I------GEEDCVEFAG--DGWNDSKCEL-KKF--WICKKSATP-CTEG-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MTVPEE------------
-------------------------------------------AR--------AQE--L-
D---SPGHLHHPI-PLALKL-----------------IFFVVFAGI--LVA--ILAQVSR
------IPS-----------------------------------------RK--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------HEQNQLL-----QK
RS--SQELARMVDII---------------------------------------------
---NRLC--RPCSWD-----WTFFHG-NCYFFSKS-QRNWHDSLTACQEAGAQLVIVESA
EE-----------------------------------------------QSFLQQ--TSK
SKGSTWMGLS--D--LNKEGTWHWVD-GSPLS------SSLGSY----WNKGEPNN----
I------GEEDCVEFKD--EGWNDGRCGN-SNF--WICKKTALS-CSNS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------SQNLKEPP----------------------------------------
----------------------------------AKQIALRSQASQISQQVD--------
---------------RLQEDGT------T-----FRSQ-----XXXXXXXXXXXXXXXX-
-------------------------------------------------XXXXXXXXXXX
XXXXSVC--KNCPKD-----WN-FQK-KCYFFGNE-PKTWPQAKFACINLQGRLVSIKNK
EE-----------------------------------------------QAFLTQK-A--
NKKGSWIGLR--D--LDMEGEFIWMD-GSPLN---------YSN----WSPGEPNNQ---
-----G-QGEDCVAMRANNGRWNDAFCRG-QQE-GWICEKLATC-PLT------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDSSGYSKWTGGPEE-VP-AGP--------
-QGPW-CWGRKAL-LVALAVM----------------VSTVLWALV--LSI--LLSKX--
---------------------------------------XXXXXXXXXXXX---------
--XXXXX-XXXXXXXXXXXXXE----VGACTTCCSEA-RAQLK-------T-----TRAE
L-------------------------------------------GEAQKKLLEQRSTL--
--------------EELRDS-----------------------VTKNVAQAGRDRNAIRT
EL--LRALEAAKLGN---------------------------------------------
----NSC--EPCPRS-----WLPFEG-SCYLFSEQ-KNTWEAALNSCQNAGAHLVIVDDL
EE-----------------------------------------------QSFLSAH-T-R
-GRGFWLGL-KAVRQLGKIQSYQWVD-GVQLT---------FSH----WNVGEPNDS---
------RGLENCIMMLHTG-LWNDAPCNN-ERD-NWICEKRRRC----------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------------------------MAEGRRS---GWQH---
AQDLTLM-G----------------EK----SLSILKKSGQQDQN-PP-DTDP--W----
------------K-FLCLAMT----------------MLMFLLVMI--VGV--LLRNVVL
L--------------N--------------------------------------------
------------------------------------------------------------
----------------------------------------YQLEEELHQ-----------
-----------------------------LNNTFTRGL----------ADARYNRDIFRG
EM--FRQMN------------------------------------------------AVQ
SENGSSC--TPCPED-----WTAFEG-SCYKFSTE-ALTWFEAKDQCIHEGAHLVIINSL
VE-----------------------------------------------QEFLTTS-Q--
--HVFWIGLK--K--HYWTGTYKWQD-GSSPT---------YTN----WSSEQLH-----
--------FLDCVFIKP-PGHWVSFYCDS-L-PFRWICEKPQTC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSESMESN----------
TQQLDNPED----------------EE-YLMSGSRYSIISSRLRT--------KFGIKS-
L---AEYTKQSHN-PLVLPL-----------------LSFLFLAGL--LLI--ILVLVSK
------VPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SEV-----QD
KI--YQELMQLKTEV---------------------------------------------
--HDGLC--QPCPRD-----WTFFNG-SCYFFSKS-QRNWHNSITACKELGAQLVIVETD
EE-----------------------------------------------QTFLQQ--TSK
TRGPTWMGLS--D--MHNEATWHWVD-GSPLS------PSFAQY----WNRGEPNN----
V------GDEDCAEFSG--DGWNDLRCDT-RIF--WICKKVSTSSCTIK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RR-RCC-----
--------RRG-T-QIVLLGL----------------VTAALWAGL--LTL--LLLWHWD
T--------------TQSLKQLEERAARN------VSQVSKNLESHHGDQM---------
--AQKSQ-STQISQELEELR----------------------------------------
----------------------------------AEQQRLKSQDLELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNEASDLLQRLRE
EV--TKLRMELQMS----------------------------------------------
--SGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWVHARYACDDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTGSWIGLR--N--LDLKGEFIWVD-GSHVD---------YSN----WAPGEPTSR---
-----S-QGEDCVMMRG-SGRWNDAFCDR-KLG-AWVCDRLATC-TP-PASEGSAE---S
M--GPDSRPGP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------MAEMCVPK---------E
P-----GGP----------------EEREIFQGQRSSEKDPGLSR--------S---SRS
L---PECLTRAPL-LL-ILLL---------ISLGL----FMLMLIT--LIQ------VSR
IQ-QSLPREVDDQ-------------------E--------S-H---S--P--G--EG--
L----------------EA--G--F-W---N---------V--V--V---L--Q---S--
-D-------L--E----E-I-----------L----------------HQLSRMNATL--
------------------------------------------------------------
------------------------------------------------------------
---TGLC--RRCPWN-----WDFFQG-SCYIFSKI-QSTWDASVSACEDMRAQLVVINNA
EE-----------------------------------------------QKFLKSW-DIR
NDKSTWIGLS--D--KHNEGSWQWVD-NTHLH------LSF-------WKEGEPNN----
Q------GEEDCVELSG--DGWNDNKCSE-EHF--WICEKPSAL-CPGL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LFQS-SCYFFANT-HKNWD-AALCCRNLKGHLVIINSP
EE-----------------------------------------------QNFLSQQ-L--
NNIQAWIGLS--D--QRTEGVWHWVD-GVALT---------LQF----WDTGEPNNS---
-----G--NEDCAEMKD-KGRWNDVTCQK-E-S-VWICETQATS-CTSLDSDLT-K----
---SSSSLPGP-------------HGL--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTAGYCKWGGGSQD-LP-GGH--------
-WGRWEHCKQRFF-FLALLLL----------------VATILWAFI--LSL--LLSKA--
---------------------------------------SVERRALVGQQD---------
--LLETN-ASEQTVVLGALKEE----VGACNSCCLGT-KAKLQ-------T-----TLTE
L-------------------------------------------GETQIKVLQQESAL--
--------------KELQER-----------------------VTQGLAEAGRDRENVRT
EL--FRVLEGIKFQN---------------------------------------------
----GSC--EPCPKS-----WLTFQG-SCYFFSEP-PSSWEAAQRLCANLSAHLVIIEGL
EE-----------------------------------------------QGFLSLH-T-R
-GLGYWLGL-RAVRHSGEVQSYKWID-GVPLS---------FSH----WNTGEPNDS---
------RRQEDCVMMLHSG-LWNDAPCNS-KMD-GCICEKRRSC-YP-------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MNTGEYNKLGSAIEE-VS-RGQ--------
-LGRWECYKQRLF-FLVLALL----------------VATVLWALI--LST--LLSSA--
---------------------------------------SSKLRVLLSHQD---------
--LLRTN-ASEQKMTLSSLKDD----IGACRNCCSVT-KAQLQ-------T-----TLAE
F-------------------------------------------KDIQAKLMEQESIL--
--------------KELQER-----------------------VTQDLAKASRDRENIRS
EL--FQALEAVKRQN---------------------------------------------
----SSC--EQCPPS-----WLPFQG-SCYYFSET-QATWDTAQSYCGGQGAHLVIVRGL
NE-----------------------------------------------QGFLSQH-T-R
-GRGYWLGL-RAVRHLNKIQGYRWVD-GASLN---------FSH----WNSGEPNDS---
------RGHEDCIMMLHSG-LWNDAPCTN-ERD-GWICEKRSSC-Y--------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRSTEEELDESLKRLQSDQAT
LREE------------VSTDLA------K-----AK----------------RDRDDIRA
ET--YRILEA------------------------------------------------AQ
KGNG--T--AGCQPG-----WEQFHR-RCYLFSST-TQRWQAARASCQSQNADLVVINDQ
ME-----------------------------------------------QNYLASK-A--
DSVRHWIGFT--D--QGTEGVWHWVD-NTTTA---------FTL----WAPGEPNNMYSF
HI-----REEDCAHLNE-DGKWNDEPCQM-R-Y-RWICEKAALQ----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGP--------
-WGRWVHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGHD---------
--LLRTN-ASKQTAALGALKEE----VGDCHSCCSGT-QAQLQ-------T-----TRAE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEAGRGREDVRT
EL--FRALEAVRLQN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
DE-----------------------------------------------QGFLTRN-T-R
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNKGEPNDA---
------WGRENCVMMLHTG-LWNDAPCDS-EKD-GWICEKRRNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHQ--Y---SGFSD-YT-RKRCC------
--------NRD-T-QLALVGL----------------LTTALWAGL--LAL--LLLWHWD
T--------------LRTMKQLEESVARN------VSQVSKDLQRYQGERA---------
--AQRSD-ASEVLRLVQKLR----------------------------------------
----------------------------------AEQN-ITPQDSRLSQNVD--------
---------------RLQEDLS------N-----FKSQ-----SLNEKRTASDLLKQLQE
EV--VKLWMKIHVA----------------------------------------------
--EGSSC--NTCPEN-----WISFQH-KCYYFGEG-SKQWVQARFTCDHLQGRLVSIHSR
EE-----------------------------------------------QXXXXXX-X--
XXXXXXXXXX--X--XXXXXXXXXXX-XXXXX---------XXN----WSPGEPNNG---
-----G-QGEDCVMMLG-SGHWNDAFCRS-RLD-AWVCERLATC-GP-PA----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHV--YSEFPNLP---G-RRRWCC-----
--------RQG-T-QMALLGL----------------VTVMLWAGL--LTL--LLFWHWD
A--------------VQNLKQLEETAAQN------VSQVAKDLERHRGDEM---------
--AQKSR-AAQVSQNMEEIQ----------------------------------------
----------------------------------AEQKRMKAQDSELSRNLDGLRSDLSN
LKSQ---------------------------------------SLNERRTALHSLERLQQ
EV--VKLWVELHVS----------------------------------------------
--NGSTC--NTCPEN-----WVNFQR-KCYYFGEG-AKKWIQARFACSKLQGRLVSIHSQ
EE-----------------------------------------------QDFLAKR-A--
NRKGTWIGLR--D--LDIEGEFIWMD-ENPLN---------YSN----WRPGEPNNQ---
-----G-QGEDCVMMQG-SGQWNDAFCGS-RLD-GWVCDRLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MAGEHEPK---------V
S-----RGP----------------EK-DTFEGQRFTQKDLEVST--------HR--PVS
F---PVLRAHWLL-LL--LLI---------LSLTI---CFLLLVTM--LVQ------VSR
IP-KSPQVEAQDH-------------------E--------E-N---L--S--L--G---
------------------E--A--A-A---S---------Q--G--P---V--H---S--
-S-------L--------------------------------------QQLSQINASL--
------------------------------------------------------------
------------------------------------------------------------
---AHLC--RPCPWN-----WEPFQG-SCYLFSRT-LGSWDSSVSCCQ-HGSHLVIINSI
AE-----------------------------------------------QRFLSYW-DIR
KSHVMWIGLS--D--HNKEGSWHWVD-NTLLQ------LSF-------WKDGEPNN----
D------GNQGCVQLAE--NTWSDNRCTA-QNF--WICEKPLTP-CPGL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----SLC--HPCQWD-----WTFFQG-NCYFFSEI-QHNWHNSVTACQEMGAQLVVIKSE
EE-----------------------------------------------QRFLQQ--ASK
SKGRTWMGLS--D--LKHEGTWHWVD-GSHLM------FRFMKY----WNEGEPNS----
S------GDEDCAEFRG--DGWNDVQCKL-EKF--WICKTSAAF-CPTK-----------
-----------------------------------------------------

------------------------------------------------------------
-----------------------------------------LTDMFKATR----------
ERSLGPVGE----------------AS-VYPEEDDLARRPRGTWS--------WKGCKV-
S---AGHL-RSHL-SLVLQL-----------------LCVLLCAVL--LVQ--VL-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------E--
---------------------V------------------------SKVPSSK-----TE
EI--HQDLMQLKAGL---------------------------------------------
---ANLC--RPCPWD-----WTFFQG-HCYFFSKS-QRNWHDSVSACQDVGAQLVIVRSD
EE-----------------------------------------------QSFLQL--NAK
SRGPTWMGLS--D--LKKEGTWHWVD-GSPLM------LSFTKF----WNRGEPND----
I------GGEDCAEFRG--DGWNDSLCNG-LRF--WVC----------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MTAPGKAQ----------
AQEQGPLDE----------------EQ-LIDSRPRNAMNRSGHRQ--------ASVFNS-
L---AGCHLHHPI-PLVLKL-----------------LMLTLFAGI--LVA--ILAQVSN
------IPS-----------------------------------------RQ--------
------------------------------------------------------------
------------------------------------------------------------
---------------------E------------------------YEQDQSQ-----QK
QV--YQELAQMKDRM---------------------------------------------
---SNLC--RPCSWD-----WTFFQG-KCYFFSKS-QRNWHDSVTACKEAGAQLVIVESA
EE-----------------------------------------------QSFLQQ--TSK
SKGVTWMGLS--D--LNKEGTWHWVD-GSPLS------SSLGNY----WNTGEPNN----
I------GEEDCAEFKN--DGWNDGRCEN-SNF--WICKKTATS-CTDAQ----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MNSISYQKWEDDQDH-PAVDKSQLAWISR-
GTGWWKKLFPQDLPSKSVSLL----------------LAVILLLSI--LLIV-SLVKG--
---------------------------------------SKTSQELKQLKE---------
--EVRT--------------------------NGSAL-WTSLG-------K-----LENK
V-------------------------------------------GDSHNRLLKLESKH--
--------------NELSTQ-----------------------MTQALAEAGKDRQDIRS
EM--FRAVAAVRRGN---------------------------------------------
----SSC--SPCPDS-----WLAFEG-SCYFFSTN-KTHWDQSQQKCAQEQAHLVIVNNL
EE-----------------------------------------------QTFLTQN-T-R
-GLGYWIGL-TATRTRGRVNGYTWVD-GSKLT---------FSY----WNIGEPNDS---
------RRNENCIMILYTG-RWNDAPCNN-LND-NWICEKRQQC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MVAE------------------------VDSRGS--------HQ
HH--SSSREHSHEA----------------------------------------------
--ICFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWVHARYACEDMEGQLVSIHSL
EE-----------------------------------------------QDFLTKH-A--
SHTGSWIGLR--N--LDLKGEFVWVD-GSHVD---------YSN----WAPGEPTSR---
-----S-QGEDCVMMRG-SGHWNDAFCDR-ELG-AWVCDRLATC-TP-PASEGSAE---S
V--GPDSRRGP-------------DGRLPA-PS-------APLHS--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------E
KV--YQELTQLKAGV---------------------------------------------
---DRLC--RPCAWD-----WTYFEK-NCYFFSMI-QKSWSDSVTACQKVGSQLVVIKSH
EE-----------------------------------------------QNFLQQ--TSK
KRGYTWMGLI--D--MNKESRWHWVD-GSPLT------LSFMKY----WNKGEPNN----
L------GEEDCAEFRD--DGWNDTKCDN-KKF--WICKRPATS-CSRK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEMG----------
KRQLRPLDE----------------EL-LTSSHTRHSIKGFGFQT--------NSGFSS-
F---TGCLVHSQV-PLALQV-----------------LFLAVCSVL--LVV--ILVKVYK
------IPS---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------S------------------------Q--EENN-----QM
NV--YQELTQLKAGV---------------------------------------------
---DRLC--RSCPWD-----WTHFQG-SCYFFSVA-QKSWNDSATACHNVGAQLVVIKSD
EE-----------------------------------------------QNFLQQ--TSK
KRGYTWMGLI--D--MSKESTWYWVD-GSPLT------LSFMKY----WSKGEPNN----
L------GEEDCAEFRD--DGWNDTKCTN-KKF--WICKKLSTS-CPSK-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRRVHWSGRPL-FLALAVL----------------VVTVLWAVI--LSI--LLSKAXX
X---XX-------------------------------XXSTERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCRSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GETQAKLMEQESAL--
--------------RELREH-----------------------VTQGLAEASRNREDVRT
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADASAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MEFFGYMKWGDGP------GG---------
------HWKSRAF-FLALAVL----------------AGTVLWALI--LSV--FLSHA--
---------------------------------------STEREELFHDLE---------
--ELSAN-ASKHGVALGTLKKD----VGTCQSCCETV-QGQLQ-------S-----ALRE
L-------------------------------------------AATQTKLLQQENSL--
--------------KELTTS-----------------------XXXXXXXXXXXXEDIRN
EL--YRALQNVQSQN---------------------------------------------
----GSC--EPCPES-----WRVFEG-SCYFFSEK-KASWQEAQQRCALASAHLVVIGSL
EE-----------------------------------------------QGFLNRN-I-Q
RDHGYWLGL-RAVRRLGRVERYQWVD-GLTMG---------FSY----WNTGEPNDS---
------RREEDCVMMLDSG-LWNDAPCRN-ERD-HWICEKRRSS-C--------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKESR----------
LQQLDLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLS--QSKQDTIYQNLTQLKAAVSDLP-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-LQEIY---------------------------------QELTR-----LKAA
VGD-------LPEKSKQQEIYQEL----TRLKAAVDELPEKSKLQEIYQELSRLKAAVGD
LPEKSKQEEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAA----------------------------------------------
--VERLC--RPCPWE-----WTFFQG-NCYFMSNS-QQNWHDSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNQEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
I------GEEDCAEFSG--SGWNDDKCNL-AKF--WICKKSAAS-CSGDEERLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
SNRLAWMGLS--D--LKQEGTWQWVD-GSPLS------PSLRRY----WNQGEPNN----
I------GEEDCAEFNG--NGWNDDRCSA-AKF--WICKKSAAS-CSRDEERLLSA---P
T----T----------------------SN-PH-------AG-----------

--------------------------------------------------M---------
-------------------------------------TKNPGVQSLVERR---PREGDSE
RVEFNTMTPHSQAEGRGPGPAVRHQGR-ASRGVQ--EPEFSKFP---R-RRRRCC-----
--------RRG-M-QLALVGL----------------MIAALWAGL--LTL--LLLWHWD
T--------------VRNLKQLEEAAALN------VSQVSKDLERHKGDQM---------
--AQKSQ-AAQMLQDMARIQ----------------------------------------
----------------------------------AEQKRMVSQESELFRNLDGLRADLSN
LKSY---------------------------------------SLNERHRALHSLGRLQE
EV--EKLWLELHES----------------------------------------------
--NGSVC--NTCPEE-----WVHFQR-KCYYFGET-AKKWIQAKYACSSLQGRLVSIHSQ
EE-----------------------------------------------QDFLTKH-A--
HIRGSWIGLR--D--LDIEGEFIWMD-EKPLD---------YSN----WQPGEPNDA---
-----G-QGEHCVMMQA-SGQWNDAFCGS-YLD--WVCERLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LS-RKKGCC-----
--------RHW-T-RTVLLGL----------------LTAALWAGL--LIL--LLLWHKD
T--------------TQNLKQLEERAARN------VSQVSKYFERYQGDQM---------
--AQKSQ-ATEISQSLEELR----------------------------------------
----------------------------------AEQQRMNSRDSELHQNLN--------
---------------GLEADLS------S-----FKSQ-----ELNERHTASDLLGRLWQ
EV--RKLQTELQVS----------------------------------------------
--RGFVC--NTCPEN-----WVSFQQ-KCYYFGKG-TKQWVHARYACEDVEGQLVSIHSQ
EE-----------------------------------------------QDFLIKH-A--
SRTGSWIGLR--N--LDLKGEFIWMD-GTPVD---------YSN----WAPEEPTNR---
-----N-QGEDCVMMRG-SGDWNDIYCDR-KLG-AWVCDRLATC-VP-PAREGSAE---P
PEPGPDSEPGQ-------------DDRLPI-PS-------ALLHP--------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------SLSLQLC--------P---SAG
S---AGCRTRLPL-LL-LPLL---------LSLGL----FLLLITI--LIQDSLVLGLSK
IH-QSMQRGAWDH-------------------Q--------E-N---E--P--P--G---
--------------------------E---A---------L--D--A---G--I---Q--
-K-------L--E----E-I-----------R----------------EQLTRMNATL--
------------------------------------------------------------
------------------------------------------------------------
---TGLC--RPCPWN-----WGFFQG-SCYFFSQT-QNTWKASVSACQDIKAQLVIIDSA
EE-----------------------------------------------QQFLKFW-DTR
NNRPAWIGLS--D--HHNEGSWLWVD-NTPVN------LSF-------WKEGEPNN----
H------GDEDCVDFYS--DGWNDDKCNR-ENF--FICEKPSVP-CPEF-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------M-E----------------GK----SLRMLGESAHWDQK-LP-QDGP--W----
------------K-FFCLTIT----------------LMLLLLVLI--LGV--VLAEVLQ
F--------------F--------------------------------------------
------------------------------------------------------------
----------------------------------------NQMQEELKQ-----------
-----------------------------LDIKFVQGL----------ADAGHKRDMMWG
EV--FRQIE------------------------------------------------ALR
AGNESSC--EPCLEN-----WMAFQG-SCYLFSTQ-SQDWFEAKDHCAKKGAHLVIINSQ
AE-----------------------------------------------QKFLRSE-E--
-NTVYWIGLK--K--QYPKGIYKWQD-GSAPT---------FIN----WPDTTSS-----
--------DNDCVFIEK-SGFWFSGMCQV-SWYY-WICEKPQVC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
LQQLGLLEE----------------EQ-L---------GGVGFRQ--------TRGYKS-
L---AGCLGH--G-PLVLQL-----------------LSFTLLAGL--LVQ------VSK
VPSSLSQGQSKQDAIYQNLTQLKVAVSELS-EKSKQQEIYQELTRLKAAVGEL-------
--PEKSK-QQEI---------------------------------YEELTR-----LKAA
VGE-------LPEKSKLQEIYQEL----TRLKAAVGELPEKSKQQEIYQELSRLKAAVGD
LPEKSKQQEIYQKLTQLKAAVD------------------------GLPDRSK-----QQ
EI--YQELIQLKAAV---------------------------------------GDPDRP
PPTERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHNSITACQEVGAQLVVIKSA
EE-----------------------------------------------QNFLQLQ-SSR
SNRFTWMGLS--D--LNHEGTWQWVD-GSPLL------PSFKQY----WNKGEPNN----
V------GEEDCAEFSG--NGWNDDKCNL-AKF--WICKKSAAS-CSGDEERLLSP---A
P----TT---------------------PN-PP-------PE-----------

------------------------------------------------------------
------------------------------------------------------------
-------DD----------------EE-LMTSGNRLSYKDFGFQK--------SHGFKN-
F---PGCRGQGRA-PLVLLF-----------------LSLMVFAGL--LVA--ILVQVSK
------VPR-----------------------------------------SQG-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------LEPSK-----QE
EI--QQILTQLKAGI---------------------------------------------
---ALLC--HPCPWG-----WRSFQG-NCYFFSNS-QLNWHDSVTACEEVEAQLVVIESA
EE-----------------------------------------------QNFLQVQ-ASR
FNRLTWMGLS--D--LKHEGTWHWVD-GSPLL------PSFVKY----WNEGEPNS----
S------GEEDCAEFRG--KGWNDSKCSL-SKF--WICKKPTTS-CSSA-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSNPKESK----------
AQQLGPLDE----------------EE-LIPGGTRYFIKGSGFQP--------TYGPKN-
I---AGSLGHGSI-ALALKL-----------------LFLLFFSAV--LVA--VLVKVSK
------VPS-----------------------------------------YQE-------
--QR--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------QAK--------Q
KI--NKEMMQLKTEI---------------------------------------------
---GHLC--RPCSWD-----WTFFQR-NCYFFSNS-KLNWSASVTACQKMGAQLVVIKDP
EE-----------------------------------------------QNFLQL--SSK
NRGPTWMGLS--D--LKKEGIWKWLD-GSHLW------YRLLKY----WLPGEPNN----
E------GQEHCAEFRG--DGWNDDNCEL-EKF--WICKKLAAS-CSEVQ----------
-----------------------------------------------------

-----------------------------MCPQIFLRGSLIPIVFLILRELRKNRSEEGL
QREIHEV--------IKTIVQTRAGKR--N-------RKGRRMAEMYEHK---------E
P-----DDS----------------EE-ETFGGQRLAERRPRLLH--------S---LRS
L---PECLAWAPL-LLLLLLF---------VSLGF----FTLQLTT--LVQ------VSR
IR--CLQRDSGDH-------------------E--------N-N---S--L--D--KW--
L-D--T---R--F-R--SL--T--E-V---A---------Q--K--Q---M--Q---S--
-N-------L--E----E-I-----------L----------------QRLTRMNATL--
------------------------------------------------------------
------------------------------------------------------------
---AGLC--HPCPQN-----WEFFGG-SCYFFSWT-QSDWRSAVSACLLTGAHLVIINST
EE-----------------------------------------------EKFLNFW-YAR
NNKPTWIGLS--D--HHSEGSWRWVD-DSPVQ------LSF-------WKKGEPNN----
H------GDEDCVELHN--DGWNDGRCVT-ENP--WICEKPSAP-CPDL-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHS--YSDPAEFPK-FS-RRRRCC-----
--------RPG-V-QLALLGL----------------VTVMLWAGL--LTL--LLFWHRD
T--------------VQNLKQLEVAAAQN------VSRVSKDLERHNGDQM---------
--AQKSQ-AAQVSQDMKEIQ----------------------------------------
----------------------------------AEQKRMKAQDSELSQNLDALRSDLNN
LKSQ---------------------------------------SLNERSTALHSLERLQE
EV--EKLWMELHVS----------------------------------------------
--NGSEC--NTCPEK-----WLNFQR-KCYYFGEE-PKKWIQARFACSKLQGRLASIHSQ
EE-----------------------------------------------QDFLARY-A--
NKKGTWIGLR--D--LDREGEFIWMD-ENPLN---------YSN----WRPGEPNNG---
-----G-QGEDCVMMQG-SGQWNDAFCGS-SLD-GWVCDRLATC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MTDAKEAK----------
GQRLGPPDE----------------EE-LIAGGPGSFMKGFG-----------LSGFKF-
S---AGCLGDYSL-PLALQL-----------------LAFTLFAGL--LVA--ILVQVSR
------SPS-----------------------------------------FQE-------
--LE--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------LEQSK-----QE
KI--YQELSQLKAGV---------------------------------------------
---DNLC--RPCSWD-----WTFFQE-KCYFFSKS-QRNWSDSVTACKEAGAQLVIVESA
EE-----------------------------------------------QSFLQL--ASK
SKGHTWMGLS--D--LNKESTWHWVD-GSPLS------LSFMKY----WNPKEPNN----
L------GEEDCAEFDG--DGWNDARCDI-NKY--FICKQSAAS-CSN------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEHA--YSEFPKFP---R-RRRQCC-----
--------QRG-T-LLALLGL----------------VTTAMWAGL--LTL--LLLWHWE
T--------------VQKLKQLEKTAAQN------VSQVSKDLEKHKGEQV---------
--AQESQ-AAKMSQSMEKIQ----------------------------------------
----------------------------------DEQNRMKSQDSELSRNLNGLREDLSD
LQSQ---------------------------------------GLNERRAALHALDRLQE
EV--AKLWIELRVS----------------------------------------------
--NGSTC--NTCPDD-----WVHFQK-KCYYFGEG-PKRWIQARFACSKLHGRLVSIHSQ
EE-----------------------------------------------QDFLTRH-A--
NKKGSWIGLR--D--LNIEGEFVWMD-QNPLD---------YSN----WQPGEPNNG---
-----G-QGEDCVMMRA-SGHWNDAFCGS-YLD-GWVCDRLVTC----------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------------------------MALNGGA----------
--------------------------D-GACENWELTKDMLLEEQ-SP-RKSPKRAVLSL
L---PSSPPRA-V-VLLALLL----------------ALSFVFLMI--LIL--VNIQRVS
-------------------------------------AMREELERA---QL---------
--QDKQS-HTTAWHNLSEVRRA--------------------------LDT----QLSAE
LQ----------E-------------------IHSRLLNVSREVEDVQQKMMQCRAECGK
ELRD--------RVR------------------ALEERDVLQPALQQLDELRQEQSHIST
LL--STALE------------------------------------------------ETQ
NLTGMFC--TRCPAG-----WQQFDK-TCYYFSTE-GKSWVEARAACSMLGAQLAIINSE
LE-----------------------------------------------NKFLANH-IME
-IRAFWLGLS--D--MQREGDWEWLD-GQSLS---------ISF----WRKGEPNNV---
-----GQHGEDCATISS-SGLWNDVTCTS-HEA--WVCERSC------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------EELKQ-----------
-----------------------------LDVKFLQGL----------EEAGHKRDIIQG
GI--FQQME------------------------------------------------AVR
AGNESSW--ESCPKT-----WKAFQG-SCYHFCTD-EPPWLKATGRCAEEGAHLV-INSQ
AG-----------------------------------------------QEFLSPK-K--
-DVTYWMGLR--K--QSSIDIYKWQS-TSPHLH-------FHRN----WSSERSY-----
--------P-DYCIFMK-FGHWTKFDCVA-YWHGYSICEKPQMC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDFKQVR----------
VQQLDPLEE----------------E--LAASSARGSLSHHALQP--------PSRAGS-
S---AGCLSSSYA-LLGLQL-----------------LSLMVLAGL--LVA--VLAQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---DRLC--RPCPWD-----WTFFQG-HCYFFSKS-QRNWHDSVTACQEEGAQLVVINSA
EE-----------------------------------------------QNFLLQ--ISK
NKGSTWMGLS--D--LNEEATWHWVD-GSPLS------PS-LTY----WNEGEPNN----
V------GEEDCAEITD--SGWNDAKCDA-EKF--WVCKTSSSS-CPNT-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSQLGPLVI--CVLLGL--------
-WGRWDYFRQRIF-LLALAVL----------------AVTVLWALI--LSI--LLSKA--
---------------------------------------STERRALLGHQD---------
--LLRAN-ASQQAVALGAWKRE----VGACRSCCNAT-KVELQ-------A-----AVAE
L-------------------------------------------REAQVKLLQQKSAL--
--------------EELSQR-----------------------VTRDLATAGRDRENIRN
EL--FRELENVKFQN---------------------------------------------
----SSC--EQCPTS-----WLPFRG-SCYYFSEP-RATWQEAQRNCAVNDAHLVIIDNL
DK-----------------------------------------------QGFVTRH-T-R
-GRGYWLGL-RGIRNAGRIQNYQWVD-GLPLG---------FSH----WNSGEPNDS---
------RGQEDCVMMLHSG-LWNDAPCGS-ERD-GWICEKRQRC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSKEPR----------
AQPLGLLEE----------------EE-LITSGMNFFPRDFGFRQ--------TRGYKS-
L---AGCLGH--A-PLVLLL-----------------LSFTLFTGL--LVA--ILIQVSK
NPSSQRQEQ----S----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------M-----QE
EI--SQDLTQLK------------------------------------------------
AAVERLC--RPCPWE-----WTFFQG-NCYFMSNS-QRNWHDSVTACQEVGAQLVIIESD
EE-----------------------------------------------QNFLQLQ-SSR
SNRLAWMGLS--D--LHEENTWQWVD-GSPLS------PRT--F----WCKKRLYKCYLP
S------TSVDCKDVPS-------------------------------------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTPGYSKWDGMSED-VS-RGH--------
-WGRWTSWRHRIF-FLALAVL----------------VATVLWALI--LSV--LLSEA--
---------------------------------------SSEREALLQHQD---------
--ALSTN-ASKHATALDTLKKE----VGACGSCCKEN-KAQLQ-------K-----AVLE
L-------------------------------------------AATQAKLLEQESAL--
--------------KELTTR-----------------------VTQEVAKASRDRENIRS
EL--YRALDNTKVQN---------------------------------------------
----GSC--EPCPDK-----WLLFEG-SCYFFSER-PDTWEQAQQQCALISGHLVIVGGL
EE-----------------------------------------------QGFLSRN-L-Q
YKYGYWLGL-RAVRRRGRIEGYQWVD-GVPLS---------FSH----WNTGEPNDS---
------RGQEDCVMMLDSG-LWNDAPCGN-TRD-NWICEKRRSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MDTTRYSKWGGSSEE-VP-GGH--------
-WGRRVHWSRRPL-FLALAVL----------------VATVLWAVI--LSI--LLSKA--
---------------------------------------STERAALLDGQD---------
--LLRTN-ASKQTAALGALKEE----VGVCHSCCSGT-QAQLQ-------T-----TRSE
L-------------------------------------------GEAQAKLMEQESAL--
--------------RELRER-----------------------VTQGLAEASRSREDVRS
EL--FRALEAVRLHN---------------------------------------------
----NSC--EPCPTS-----WLSFEG-SCYFFSVP-KTTWAAAQGHCADAGAHLVIVGGL
EE-----------------------------------------------QGFLTRN-T-G
-GRGYWLGL-RAVRHLGKVQGYQWVD-GVSLS---------FSH----WNQGEPNDA---
------RGREDCVMMLRTG-LWNDAPCDS-EKD-GWICEKRHNC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----RLC--RPCSWD-----WTFFQS-NCYFFSDS-RLNWSDSVAACQEMRAQLVVIKSP
EE-----------------------------------------------QNFLQL--NSK
NRGPTWMGLS--D--LKKEGIWHWLD-GSHLW------FRFTKY----WLPGEPNN----
D------GKEDCAEFRG--NGWNDGKCER-QKF--WICKRPAAS-CSDM-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEENE--Y---SGYWE-PP-RKRCCC-----
-------ARRG-T-QLMLVGL----------------LSTAMWAGL--LAL--LLLWHWE
T--------------EKNLKQLGDTAIQN------VSHVTKDLQKFQSNQL---------
--AQKSQ-VVQMSQNLQELQ----------------------------------------
----------------------------------AEQKQMKAQDSRLSQNLTGLQEDLRN
AQSQ--NSKLSQNLNRLQDDLV------N-----IKSL-----GLNEKRTASDSLEKLQE
EV--AKLWIEILIS----------------------------------------------
--KGTAC--NICPKN-----WLHFQQ-KCYYFGKG-SKQWIQARFACSDLQGRLVSIHSQ
KE-----------------------------------------------QDFLMQH-I--
NKKDSWIGLQ--D--LNMEGEFVWSD-GSPVG---------YSN----WNPGEPNNG---
-----G-QGEDCVMMRG-SGQWNDAFCRS-YLD-AWVCEQLATC-EI-SAPLASVT---P
TRPTPKSEP--------------------------------------------

------------------------------------------------------------
------------------------------------------MSDSTEAR----------
TQQLGALDD----------------EE-WMISGTNYSVKTSGSLP--------YSGIKS-
F---TGCLGRGH---MVLQL-----------------LAFLFLAGL--LVI--TLAQVSK
IS--------------------------------------------------Q-------
--GHNNS-MQKFFEQLTQLEAE----LFSKIPISQGQNESMQ-KISEQLIQ-----LKAE
LSE--SPENQGPGASG-LILNNNI----MGLKRCLISK-----------------ITI--
---------------------I------------------------QKQDDSK-----QE
KI--SQQLTQLQAQL---------------------------------------------
---YSLC--CPCPWD-----WTSFVG-NCYFFSMS-QRNWNDAVT----MGAQLVIIKSE
EE-----------------------------------------------QTFLQQ--TSK
AKGRTWMGLS--D--FNKEAALM-----SYGL------FSFQKY----WNKGEPNN----
I------GEEDCAEFSG--DGWNDSKCDL-RKF--WICKKAETL-CTTS-----------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MQEELKQ-----------
-----------------------------LDIKFVQGL----------ADAGHKRDIMWG
EV--FRQVE------------------------------------------------AVR
AGNESSC--EPCLEN-----WMAFQG-SCYQFSTQ-LLDWFKAKDDCAEKDAHLVIINSQ
AE-----------------------------------------------QKFLSPK-E--
-DVGYWIGLR--K--QYPKGIYKWQD-GSVPT---------FDN----WTNTESF-----
--------YYDCVILWK-FGTWFSSTCSV-YWYH-WICEKPQIC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------TQNLKQLEDRAAQN------VSQVSKNLERQHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNQRNAASDLLERLRE
EV--TKLRMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTISWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPTNQ---
-----S-HGKDCVMMRG-SGHWNNAFCDR-KLG-SWVCDRMATC-AP-PANEGSAE---S
L--GPESRPGP------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MDTTTKYSKWDSRPEE-VP-RGP--------
-WGCWEYGSRRPL-FLALAFL----------------VATVLWAVI--LSI--LVSKA--
---------------------------------------STESGALRGSQD---------
--LLRRN-ASKQTTVLGALKEE----IGACHNCCSGA-HVELQ-------T-----MSAE
L-------------------------------------------GKAQAKLMEQESAL--
--------------KDLSEQ-----------------------VTQGLAKAGRDREDVRS
EL--FRVLGTIRFQN---------------------------------------------
----SSC--EPCPAS-----WLPFEG-SCYYFSEN-KASWVAAQTHCAGASAHLVIVGGL
EE-----------------------------------------------QNFLTRN-T-A
-GRGYWMGL-RAVRHLGKVQSYQWVD-GVALS---------FSH----WNQGEPNDS---
------RGRENCVMLLHTG-LWNDAPCDN-ERD-NWICEKRHSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------MGSSEESK----------
AQQLGPLDE----------------EE-LITSGPRSFMRGLGWQR--------ISGFNC-
S---AGY-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----RLC--RPCPWD-----WTLFQE-KCYFFSKS-QRNWNDSSTTCKEKGAQLVIVDSD
EE-----------------------------------------------QSFLQM--ASK
SKGRTWMGLS--D--LNMESKWHWVD-GSLLS------LSLMKY----WNPNEPNN----
L------GEEDCAEFAG--DGWNDARCEV-QKY--FICEQSAAS-CSS------------
-----------------------------------------------------

------------------------------------------------------------
-------------------------------------------MSEGKGG---GWGV---
PKELPAV-G----------------PD----PPPRPWQAGRSVQK--P-QVKT--W----
------------K-YLCLVVC----------------LILLLLAVI--LSQ--FLPKAFE
K--------------T--------------------------------------------
------------------------------------------------------------
----------------------------------------KQVQEDIIQ-----------
----------------------LQRK----GVPVTQGL----------ADAGHDRDFIRG
EM--FRQIE------------------------------------------------SVR
AGNESSC--QPCAPA-----WKAFQG-SCYFFSTD-NLTWTQANESCAQKQAHLVIINSQ
AE-----------------------------------------------QDFLTPT-E--
-QVTHWIGLF--L--KDGGGGHRWTD-GSIPT---------YTN----GDPKELHDD---
-----G-TNSTCVMMLH-HGLWQGFPCEL-ESS-VYICETRQSC----------------
-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------MEEGQ--Y---SEIEE-LP-RK-RCC-----
--------RRG-T-QIVLLGL----------------LTAALWAGL--LTL--LLLWHWD
T--------------TQHLKQLEERAAQN------VSQVSKNLERQHGDQM---------
--AQKSQ-STQIWQDLEELR----------------------------------------
----------------------------------AEQQRLKSQDSELSWNLN--------
---------------GLQADLS------S-----FKSQ-----ELNERNTASDLLERLRE
EV--TKLRMELQVS----------------------------------------------
--NGFVC--NTCPEK-----WINFQR-KCYYFGKG-TKQWLHARYACEDMEGQLVSIHSP
EE-----------------------------------------------QDFLTKH-A--
SHTISWIGLR--N--LNLKGEFIWVD-GSPVD---------YSN----WAPGEPASQ---
-----S-HGKDCVMMRG-SSHWNNAFCDR-KLG-SWVCDRLATC-AP-PANEGSAE---S
L--GPESRPGP-------------DGRLSA-PS-------APLHS--------

Query Results

"ENSGT00760000118924_4"

ENSGT00760000118924_4