Query Results 

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----------PASVAILSQADGTSLDVTVRPGQSVMVNISTKAEMIGSSTFRHAVLIHSD
RTISAQAINTKPNTGELTLLRPVQALGTEYFVLTPAGILAKNVKEFAVVAGAAGASVSVH
LKGVVTFRGKLYPAGNILSVTLEPYHVAQVQSTTDLSGSKVTASSPVAVLSGHSCAQKHT
NCNHVIEQLLPTSAWGTQYVVP-ALSS----QTRYDLAYV-LASQTTKLTYSHGSTTASR
RLRAGDVIEYEVRPSQPLYLSADVGIQVLLFGTGAIRDGVTYDPYLVLIPDVTAYCPAYV
FSSMPGSKGVALVVAQTKAVDDLTV--DA-HRLGAKLTWTAVRGSEFSYAEVDFDTANVI
HT---AKATANFGLLTFGLVQFGGYGTAAACGQSLLQEEKPTCQGV-QCPPSQLCQVAGG
KARCVPVSVAT

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELYSE--DQTLPAFSVEAKNE
HRGSRRVSYVGFVTVRAYSHSVSLARGEVGFVRIDSQRSRLPASLTEGRLRVYQSA-RAI
VELD----FGLVVTYNWDSQLALSLA-RFDVYLC----NYNGDP-DDYHTPDW

ENSGT00760000118896_8_Linker_4_8 (654, 706)

EQ-----
--------APNAVEFAKSWKLDDEDYLCEDGCQSNCPSCTPGQAQ

PF08742 // ENSGT00760000118896_8_Domain_8 (706, 781)

HYEGDRLCGMLTKPN
GPFAACHNTLAPRPFLEECVYDLCVASGDRSSLCRGLSAYAQACLELGVSIKDWRTQANC

ENSGT00760000118896_8_Linker_8_9 (781, 784)

PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYEVCGPACPPSCNPAAAPANCSGLPCVEGCACLPGFVASGGACVAAAS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF02345 // ENSGT00760000118896_8_Domain_10 (839, 897)

GC
TYQGRPLAPGQQVWGDEQCRRRCTCDGAT-QRVSCSDTQGCPTGERCRVQNGLLGC

ENSGT00760000118896_8_Linker_10_11 (897, 904)

YPDS
FGS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1062)

CQASGDPHYVSFDGRRFDFMGTCTYLLAGSCGQN--AMLPAFRVLMENEHRGSQTVS
YARAVLVEARGVKVAVRRKHPGQVLXXXXXXXXXXQAADGQVQV-RQGRDAVVRTDFGLT
VTYDWNARVTVKVPSSYAGALCGLCGNFNGNSRDDLALRAG

ENSGT00760000118896_8_Linker_11_13 (1062, 1115)

GQAA-------NALAFGKS
WQEETRP-GCGTTEPGDCPK-------LDSLVAQ

PF08742 // ENSGT00760000118896_8_Domain_13 (1115, 1190)

QLQSKNECGILADSEGPFRECHDTLD
PQGAVRDCAYDLCLLPGQSGPLCDALAAYADACQAAGATVHPWRSEKIC

ENSGT00760000118896_8_Linker_13_14 (1190, 1204)

P----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSRGCPLSCGDLPVPGGCG-SACHEGCVCDEGFALSGES
CVPLPSCGCVYQGTYHPPGQTFY--PGPGCDALCECQEGGLVSCKPSTCGPHEACQPSGG
ILGCVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1498)

CRASGDPHYTTFDGRRFDFMGTC-VYALAQTCGT-RPGLGQFAVLQENV
QWNS-RAVSVTRVVTVQVANFTLRLEQNQKK-VTVDGVDMKPPVVLAQGRV---RVS-QH
GSDF-VIETD-FGLR-VAYDLVYNVRVTVPGNYYQQLCGLCGNYNGDPKDDFRKPDGS--
-----------------QAGSPNEFGNSWEVKVPGSPCLPPPT--CKPGEDLXXXXXXXX
XXXXXXXXXXX-------------------------------------------------
--------------XXXXXX--X-------------------XX-----X----------
---------------------------------------------XXXXXXXXXX-----
--------------------------------XXX--XX---------------------
---------------------------------------------XX-X-X-X--X-X-X
-X-----------------------------------------------X-X-X-X-X-X
-X-X-X--------X-X-X--X-X-X-X-X-X-X-X------------------------
--------------------------------X--X--X--X--X-X--X----X--X--
X----X--X--X--X--X------------------------------------------
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-----------X-XX-X-XX-X-XX-XX-----------------------------X--
-XX-X-XX-X-XX-X--------------------------------------X-XX---
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-------------------------------XX-XX-X----------------------
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----X-X----------XX-X-XXXXXXX-------------------------------
---------------------------------XXXXXX---------------------
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-----------X------------------------------------------------
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-------------------------X------XXXXX----XXXXXXXXXXXXXP

PF02345 // ENSGT00760000118896_8_Domain_57 (4736, 4829)

GQTVL
LDS----------------------CRQQCVCHAGKG----------------------L
ACQNHSCELGQLCQSSAGI------LSCVK-EPCHGVTCRPQ------------------
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-------------------------------------ETCQEKGSQGVCVPNYEAT

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYHSFDGRDFDFQGTCNYVLVTT-SCPGVTTEDLTTFTITTKNENRGNPAVSFVRLV
NVTVLSINISIHKGEVGKVRV-NGVLTALPVSVAGGRLSVTQGASKAVLAANFGLRVSYD
WNWRVEVTLPSSYHGAVCGLCGNMDRSPSNDQAFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5605)

TLAP-----AIPIWGGSWRAPGW
DPLCWDEC---QGSCPTCPEDQLE

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

KYKGPGFCGPLAAGMGGPFAACHAHVAPDSFFKGCV
LDVCLGSGAHDILCQALATYAAACQAAGIVIKDWRAQAGC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

EIA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPSNSHYELCGPPCPAS
CPSPAPLTTPVPCDGPCAEGCQCDSGFVLSADSCVPLDGG

ENSGT00760000118896_8_Linker_75_76 (5741, 5742)

C

PF02345 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANNTYHEAGSEFWADD
TCSQRCRCGP----GGGSLTCKSARCGLGETCALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

HPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5996)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSGPCQAP-PAGVENFTVTVVNEHRGS--QAV-SY
-----TRSVTLHIYNRSLTLGARWPRQLQV--------DGKLLALPFQLDS-RLRAHLSG
P--DVVVTAASGLSLAFDGNSYVRLRVPAAYAGALCGLCGNYNRDPADDLTVVGG

ENSGT00760000118896_8_Linker_77_82 (5996, 6036)

DPA--
------GWKVGGAAGCG-ECVPGPCPAPCTPEQQK

PF08742 // ENSGT00760000118896_8_Domain_82 (6036, 6126)

PFGGPDA-------------CGVIS
A-PDGPLAPCHGLVPP-AQYFQACLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR
RPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYEVCGDSCPVSCPSLSVPEG-CKP--ACREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF02345 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHEGHYYPLGE-FYPGPQCERRCECGPGGQVSCQEGTACRPYEECRIEDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HSPGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CLANGGIHYVTLDGRAY-DLH-------GSCSYVLAQVCHPQPEDEDFAIVL
EKNAAGD-PQRLLVTVAGQVVSLAKGP--QVTVDGETVALPVA--VGHVRVTAEGRNMVL
QTTKKLRLLFDGDAHVLISIPSSFRGRLCGLCGNFNGNWSDDFVLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6451)

IVAPSVYAFGAA
WRAPS-S-SQGCGEGCGPQGCPVCFAEETA

PF08742 // ENSGT00760000118896_8_Domain_88 (6451, 6538)

PYESVKVCGQLKDPQGPFVACHAALSPSEY
FRQCVYDMCAQ-GNSTFLCRSLTAYTAACQAAGMAVKP-WRTXXXXXL-------QCPTHSHYSVCTRSC----PGSCAALSGLMGCTSRCFEGCECDDHFLLSQGICVPVQDCGCTHDGRYLPVNSSLLSSDCTERCSCSPSTGLTCQATGCPLGHVCEVEAGARDCWVPPS-LCTLSVGTNLTTFDGAHSAISIP---GIYELSSRCPGPQK-TVPWYRVLADVHSCHGKVEAVSQAHIFFQGGLVTVTPRKGV-WVN-GLRV----DLPAEVLTSVFVSRNPDGSVLVQQKAGVQVQLGTNGQLAVVVSSDHAGMLCGACGNFDGDQTNDGHGSQGNTTVESWRAQDFSPCDG----

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPTH
SHYSVCTRSC----PGSCAALSGLMGCTSRCFEGCECDDHFLLSQGICVPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF02345 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTHDG
RYLPVNSSLLSSDCTERCSCSPSTGLTCQATGCPLGHVCEVEAGARDC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

WVPPS-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6820)

CTLSV
GTNLTTFDGAHSAISIP---GIYELSSRCPGPQK-TVPWYRVLADVHSCHGKVEAVSQAH
IFFQGGLVTVTPRKGV-WVN-GLRV----DLPAEVLTSVFVSRNPDGSVLVQQKAGVQVQ
LGTNGQLAVVVSSDHAGMLCGACGNFDGDQTNDGHGSQGNTTVESWRAQDFSPCDG----
-

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--------------------------------MGSPWKWWAL----------W-------
--------------------------AGATLLWALLTPAEASCQGI-QCASGQRCQMVSG
KARCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGS--DETLPAFSVEAKNE
HRGSRQVSYVGLVTVYAYSHSVSLVRGEIGFVRIDNQRSRLPASLSEGRLRVHKSGTRGV
IEMD----FGLVVTYDWDGQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DLDQ-----
--------APDALEFANSWKLDDGDYLCDDGCHNSCPSCTPGQTQHYKGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLST
GPFSACHEFLDPKPFLDDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRLPAS

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSCYDPCSPACPPSCNSEAVPTNCSSRPCVEGCVCLPGFVASGGDCVPVSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
IYQGRLLAPGQEVFDDDRCRRRCTCDGAT-QKVTCRDTTGCPSGERCNVQNGLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1059)

CQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQN--AALPAFKVLVENEHRGSQTVS
YTRAVRVVAHGVEVAVRRENPGRVLIDGVLQYLPFQAAGGKIQVYRQGNDAIVSIDFGLT
VTYNWDAHVTAKVPSSYAKDVCGLCGNFNGNPDDDLAL

ENSGT00760000118896_8_Linker_11_13 (1059, 1121)

KGGGQAS-------NVLDFGNS
WQEEIIP-GCGATEPGDCPQ-------LDSLVTQQIQDKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPEGPFRECHKLLN
PQGAIRDCVYDLCLLPGQSGPLCDALAAYAAACQAAGGTVHPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPNS---------HYEQCSYGCPLSCGDLPVQGGCG-SECREGCVCNEGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHEGAYHAPGETFY--PGPGCDSLCHCEEGGLVSCEPSSCGPQEACQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGTTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYVTFDGRRFDFMGTC-VYVLAQTCGN-RPGLHQFTVLQENE
AWGN-GKVSVTKVITVLVANYTLRLEQSQWK-VKVNGVDTKLPVMLDGGKI---RVS-QH
GSDV-VIETD-FGLR-VAYDLVYYVRVTIPGNYYKQMCGLCGDYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QTTDPSDFGNSWEEAVPDSPCAPV-P--PCT-GDDCDT--ECS
PELQDKYHGEQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTS------------------------------------------
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-----------------------------------------------PTGPLAACHKLLD
PQGPLQD---------------CVFDLCLGGGNQSILC-------------------NII
HAYVSACQAAGGQ--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
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---------------------------------------CSLGCWALNTPQ--QCPE---
---------GCAEGCECDSGFLYNGK------ACVPI----EQ

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEESVL
IE----------------------NCQQHCVCQPGKG----------------------M
MCQDHSCKPGQVCEPSGGV------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCHGITCRPQETCK-----------VQG
GEGVCVPNYNST

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYNSFDGW----------------SFDFQG-TCNYLLAGT-
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---------------------------LCPGVNAEGLTPFTVTTKNENRGSPAVSYVRQV
TVTTLNTNISIHKNEIGKVRV-NGVLMALPVYLAGGRISVINGGSKAVLETDFGLQVTYD
WNWRVDVTLPSSYHGAVCGLCGNMDKNHQNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5620)

TMAP-----SIPTWGGSWQVPGW
DPLCWHEC---QGSCPTCPEDRVEEYEGPGFCGPLAPGT

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

GSPFTSCHAHVPPESFFKGCV
LDVCLGGGSKDILCQALAAYAAACQAAGIKIEDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPARHTAPTVCDGPCVEGCQCDEGFVLSADQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYYEAGTEFWADT
TCSKRCHCGP----GGDSLVCKPASCGLGEECALLPSGEIGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTSI----------TE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5992)

C
QAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHEP-PTGTEYFNVTVANEHRGS--QAV-SY
-----TRSVTLQIYGLSLTLSAQWPRKLQV--------NGEFVALPFHLDQ-KLSVYISG
A--DVVVNTASGVSLAFDGDSFVRLRVPAAYAGTLCGLCGNYNKNPNDDLT

ENSGT00760000118896_8_Linker_77_82 (5992, 6056)

AVGGKPE--
------GWKVGGAPGCD-QCEPEPCPKPCTPEEQEPFRGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIT
A-PEGPLAPCHSLVPP-TQYFEACLLDACQVQGHPGGLCPAIATYVAACQAAGAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYQLCGDSCPVSCPSLSAPVG-CET--ICREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLYQGRYYVLGATFYPGPECERLCECGPDGQVTCQEGADCEPYEECRIENGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGH

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGLHYVTLDGRVY-DLH-------GSCSYVLASVCHPKPGDEEFSIVL
EKNSAGD-PQRVVVTVAGQVVGLARGP--QVTVDGEVVTLPVA--TGHVSVTAEGRNIVL
QTNKGMKVLFDGDAHILMSIPSSFRGRLCGLCGNFNGNWSDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GAVAPNVEAFGTA
WRAPGS--SLGCGEGCGPQGCPVCLAEETQAYEKNDA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKIRDPHGPFAACHKVLSPLEY
FRQCVYDMCAHKGDKAYLCRSLAAYTAACQAAGAAVKP-WRTDSV

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTRSC----QGSCAALSGLTGCTTRCFEGCECDDHFLLSHGVCIPAQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCVHNG
QYMPVNSSLMSSDCSERCFCSPNNGLTCHEAGCPSGHVCEIQAGVREC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QAARG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6819)

CSISV
GANLTTFDGAHNAISSP---GVYELSSRCPGLQK-NVPWYRVLADVQPCHNNDKIVSKVH
IFFQDGLVTVIPSKGA-WVN-GLRV----DLPATVLTSVSVRRMPDGSMLVHQKAGVTVW
LGKDGLLDVMVGDDLAAMLCGACGNFDGDQTNDAYGSQGKTPIEKWRAQDFSPCSN----
-

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---------------------------------------------K-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPNSHYEPCGSSC-----------------------------------------------
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-------------------------------------------------------PETCM
GPLGASCPLPCGETCACDAGYVHSGP------DCVLRHPGPGG

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF02345 // ENSGT00760000118896_8_Domain_57 (4725, 4866)

GCTHQGHLLGPGETLW
EG---------------------VGCTRHCLCPASGG---------------------SV
ICTEVGCSPGERCVLSHGL-----------------------------------------
--RTC

ENSGT00760000118896_8_Linker_57_60 (4866, 4873)

VPSGIAT

PF00094 // ENSGT00760000118896_8_Domain_60 (4873, 5106)

CVAAGGGHYITFDGR----------------RFRFPG-SCMYLLSGLS
SQV--------PQELADFRVLLGTGPDGVPSS-------------LEVLVSGCHLRLDPK
EPGRVLVNGDWQNLPFQALSNSTLIFRHGWDTVVSCPFGLRVTYAP-------GIRVVVD
LPAAYMGHVV--GL----------------------------CADYNGDPIDDLHVPGI-
-----

ENSGT00760000118896_8_Linker_60_59 (5106, 5160)

VL----GTKLPEDALAWAFGHSY-LVGSPTGCLNAADKMPPLPPSCVTLPTTST

PF08742 // ENSGT00760000118896_8_Domain_59 (5160, 5248)

P
AYFTHICDILLDPLGPFQLCH-EMLAPGPYV------QDCMVDVCLGTGPCPMLSLYCET
C--QLLG--------GQVFPWRKSSLC

ENSGT00760000118896_8_Linker_59_67 (5248, 5253)

SPL--

PF01826 // ENSGT00760000118896_8_Domain_67 (5253, 5337)

CPAHSHYTLCAPDCSA-TCAGQKPPPGC
D-------------------------SP---GLCREGCVCDAGFLLSGAVCVPMAQ

ENSGT00760000118896_8_Linker_67_70 (5337, 5397)

CGCQ
---GYFEPGEPLPPPHPA-TSRCCSCHPGGRVACKPCRA--AR--------GGPGL

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CFAS
DGLRYRTFDGTTFHLPDACTYSLVGTGT---GSLRGVWPFEVVLEK----GPRTPELRRV
LLCVHGHRFGLDWEDWGYIRV-DGVRRCLPFALTRGRVRAFARGASVVLAVRGGPRLLFE
LGGHLSVELPAAYRGLTRGLCGNFNGNASDDLQLRGP

ENSGT00760000118896_8_Linker_70_74 (5558, 5605)

GPCA-----MPRPCPG-------
------------SGCPPARRR---

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

-AAGRGACGLL-REPSGPLAPCHALLPPEPFFQACV
ADVGRARGKREVLCAFLQAYVAACQTAGADMRPWRAPSFC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

PMR

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPPHSHYSLCVNPCPAA
CPGVQEV---VQLPTPCSEGCECEDGFFPAGRDCVPVD-HCPCFHNGQYFPPGQTVLIKN-CSSSCACQLGEGVACVPFSCPTEEICGIT------DGVLGCRL-------QGAQKSLVCTATGDFHFHTFGGTHYEFPGSCVYRLAGLCGTA-HANLEPFSLDLTP-----------LLRPRGWTKALTLLACGLRLDMSPKDLNHIR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDGEHCRLPWVLAEGRAWATVEGRYVVVYTACGLHLMYDWGSQVYLTVPSTFHGQLVGICGAFRGKLGPLDLTLDQ-RSWPKGLVTNSCPLPQP--NLDFNI--------SCPTQLAQIVNASKLCRLLQAPDGPFGRCLGHISAKPFLRICLQDRCHTHGQHLGLCDALTAYTAACQEAGISVKL-WRGPKLCPL-------TCPPRSHYSICTWTC----DGGCVQPTSPAHCSTQCYEGCECDPGLIFDGTDCVSQEHCGCFHSGRYIPVGEALVLPGCQEHCMCLRGQGLQCRPFSCPQGTGCILDGGVRYCEAGEGATCHLEPGGLFTTFDGFS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------

PF02345 // ENSGT00760000118896_8_Domain_76 (5740, 5803)

HCPCFHNGQYFPPGQTVLIKN
-CSSSCACQLGEGVACVPFSCPTEEICGIT------DGVLGC

ENSGT00760000118896_8_Linker_76_82 (5803, 5820)

RL-------QGAQKSLV

PF00094 // ENSGT00760000118896_8_Domain_82 (5820, 6411)

C
TATGDFHFHTFGGTHYEFPGSCVYRLAGLCGTA-HANLEPFSLDLTP-----------LL
RPRGWTKALTLLACGLRLDMSPKDLNHIR-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VDGEHCRLPWVLAEGRAWATVEGRYVVV
YTACGLHLMYDWGSQVYLTVPSTFHGQLVGICGAFRGKLGPLDLTLDQ-R

ENSGT00760000118896_8_Linker_82_88 (6411, 6451)

SWPKGLVTNS
CPLPQP--NLDFNI--------SCPTQLAQ

PF08742 // ENSGT00760000118896_8_Domain_88 (6451, 6527)

IVNASKLCRLLQAPDGPFGRCLGHISAKPF
LRICLQDRCHTHGQHLGLCDALTAYTAACQEAGISVKL-WRGPKLC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------T

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPPR
SHYSICTWTC----DGGCVQPTSPAHCSTQCYEGCECDPGLIFDGTDCVSQEH

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF02345 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCFHSG
RYIPVGEALVLPGCQEHCMCLRGQGLQCRPFSCPQGTGCILDGGVRYCEAGEGATCHLEP
GGLFTTFDGFS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

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--------------------MRIFGVTI------------TAVKHEF

PF00094 // ENSGT00760000118896_8_Domain_53 (3948, 4027)

GFVQVDQQRIRLP
ATLHGGRLRLHFRSSELWAEAGLKQEPAALRLVYDWQHALSLQLAEGYRAHVVGLCGNFN
QDPIDD

ENSGT00760000118896_8_Linker_53_55 (4027, 4106)

VGGPDL------------RAFLRSWALQPPDAPCHALWAAPCANP---------
-------A----------SPAETPG

PF08742 // ENSGT00760000118896_8_Domain_55 (4106, 4244)

PC---------------AILADLNGPFSPCHDVLL
PAPFEIS---------------CRAWICPFPNYRPALC-------------------LTL
QVYAHACQRLGVN--------------------IDSWRFQTGC

ENSGT00760000118896_8_Linker_55_56 (4244, 4260)

SIK-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4716)

C
PQNSHYEPCGSSC-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------PETCM
GPLGASCLLPCGETCACDAGYVHSGP------DCVLQRWGPGGCGCTHKGRLLGPGETLW
EG---------------------VGCMRRCVCPASGG---------------------SV
ICSQGGCRPGERCILSHGL-----------------------------------------
--RTCVPWSMAT

PF00094 // ENSGT00760000118896_8_Domain_61 (4873, 5097)

CVAAGGGHYITFDGR----------------RFRFPG-SCVYLLSGLS
SPT--------PQELADFRVLLGTGPDGVPSS-------------LEVLLSGYHLKLDPK
EPGHVLVNGDWQNLPFQALSNRTLIFRHGWDTVISCPFGLRVTYAP-------GIRVVVD
LPAAYMGHVA--GL----------------------------CADYNGDPSDDLQV

ENSGT00760000118896_8_Linker_61_59 (5097, 5164)

PGI-
-----VL----GTNMPEDALVWAFGHSY-LVGSPTECLNAADKMPPPPPSCVTLPTTSTP
AHF

PF08742 // ENSGT00760000118896_8_Domain_59 (5164, 5248)

AHICDILLDPLGPFQLCH-EMLAPGPYV------QDCIVDVCLGIGPCPMLSLYCET
C--QLLG--------GQVFPWRNSSLC

ENSGT00760000118896_8_Linker_59_68 (5248, 5253)

SPL--

PF01826 // ENSGT00760000118896_8_Domain_68 (5253, 5337)

CPAHSHYTLCAPDCSA-TCAGLKTPPGC
H-------------------------GP---GLCREGCVCDAGFLLSGADCVPQAQ

ENSGT00760000118896_8_Linker_68_70 (5337, 5397)

CGCL
RAGRYLEPGAPLPPPHPA-TNRCCRCHAGGQVVCKPCRA--AR--------GRPGV

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5556)

CLAS
DGLRFRTFDGTTFHLTDACTYSMVSTGM---GRLRGVWPFEVVLEK----GPQTPELRRV
LLRVHGHRFDLDWEDWGNITV-DGVRRCLPFVLTNGRVRAFARGASVVLAVRGGPRLLFR
LGGHLSVELPAAYRGLTRGLCGNFNGNASDDLQLP

ENSGT00760000118896_8_Linker_70_74 (5556, 5609)

QPGPCG-----APHPCPG-------
------------SGCPPAAGNAGADAAW

PF08742 // ENSGT00760000118896_8_Domain_74 (5609, 5681)

RGACGLL-REPSGPLAPCHALLPPEPFFQACV
ADMGHAHGNRKALCAFLQAYVAACQTAGAEMRPWRAPSFC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

PMR

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPRHSHYSLCVNPCPAA
CPGVQEV---VRLPTPCAEGCECENGFFPAGRDCVPVD-HCPCFHNGQYFPQGQTFWTDN
-CTQQCHCPTLGTLVSKLPQCWPDKCHGHCK--ASIGGWYHCLLVPSPPSPTVVEKSLV

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5981)

C
AATGDFHFHTFGGTHYEFPGSCVYRLAGLCGTA-HANLEPFSLDLTP-----------LR
RPRAWTKALTLSACGLRLDMSPKDLNHIRV--------DGILESLPFFHGH-CLRAYYQG
H--QLCVDTDFGLSLTYDWDSLARVTLPRLYGPYLCGLCG

ENSGT00760000118896_8_Linker_77_82 (5981, 6041)

QHSPS-------------SP
TMQVPDTWKVAEVPGCGPFCG-PLCPGPCPEAKRTGFAGD

PF08742 // ENSGT00760000118896_8_Domain_82 (6041, 6126)

AY-------------CGLLT
A-AEGPFGSCYAALDP-LPFMNHCLDDVCRHYGARHIVCRALTAYTVACQALGVRLRPWR
TPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PLL

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPPHSHYELCGPCCPATCAGPESCSGRGASGSRCCEGCVCDAGFVLSGASCV
PVAKCGCLRAGRYRALGAAWYPGPGCTRRCHCGPGGTVTCGP-RPCRRGRVCGLRGGERR
CLPEGRGS

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6397)

CALAGPEHVLAFDGRVL-TLPPPAPFPSGPCLHLLARSG--SQGPCGFSLDA
ARDGAGL--LSLHLNISGHHLQLHRSLVGVITVDGEHCRLPWVLAEGRAWATLEGRHVVV
YTACGLHLMYDWDSQMRLTVPSTFHGQLVGICGAFG

ENSGT00760000118896_8_Linker_85_88 (6397, 6454)

GKVGPLDLPPDK-RSWPKGLFTNP
CPLPQP--NLDFSI--------SCRTQRAQIVN

PF08742 // ENSGT00760000118896_8_Domain_88 (6454, 6527)

APELCRLLQAPDGPFGRCLDHISPKPF
LRICLQDICHTQGQHPGVCDALTAYTAACQEAGIPVTL-WRGPKLC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PM-------A

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPLR
SHYSICARTC----DGGCVEPTSPAHCSPQCYEGCECDPGLIFDGTDCVSQDHCGCFHSG
RYIPVGESLVLPGCQERCMCLRGQGLQCQPFSCPQGTGCILDGGVRSCETGEGAT

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6814)

CHLEP
GGHFTTFDGFSGLTPMPVTSCAYELATVV-GSRTEDPDWFHVIADFLPCPGCTTRKPRVI
IGFRDGCAAVGANQEIWWVN-GQPA----RLPVRVCRGVVARWAEGSQVIIERSPTLRVL
VGPEGAVALRASPALQGRLRAACGDYNGIAADDL--------------------------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGPPWSWWAL----------W-------
--------------------------AGASLLWARLAPTEASC--V-QCPPGQRCQMESG
KARCVPEPRAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCTYVLTELRST--KDSLLAFKVEAKNK
HRSSNKVSYVRLVTVHAYDYTVSLMYGEIGFAKINYQYSVLPVSLSKGRLRVYQSGTRGI
IELD----FGLVVTYDWDCLLSLSLPKRFQDQVSGLCGNYNGDPADDFLTPDG

ENSGT00760000118896_8_Linker_4_8 (654, 713)

KQ-----
--------ASDVLNFTKSWKVQDKDLLCDDGCYGNCPSCIPSQAEIFKKDPF

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLILPS
GPFADCHKFLDPKPFLEECVYDMCVTGGERLTLCHGLNAYALACVDMGISVREWRSRTN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLT

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYELCSPACPASCNSEALPTNCSSRPCVEGCVCFPGFVASRGLCMPVSSCGC
TFQDRLLAPGQEVYADEKCHLRCTCDADF-QEVICRNTSGCLLHEHCGVRNGSFGCSPEY
FRI

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1056)

CRASGDPHYMSLDERIFNFMGTCTYLFTASCGQH--PSLPDFKVFIENERRGSQSVS
FVRSVKLEAFGISLEVRREYQGKVLMNGILHYLPFQALGGKLVVFRQGKYAILRTNFSLT
ISYNWDTHVTAKVPSNYFKGVCGLCGNFNGDPRDD

ENSGT00760000118896_8_Linker_11_13 (1056, 1121)

LGVQIRGEAL-------DPRDFGKK
WLVSSHP-GCRTDEQLLCPS-------FKKEIVK--SITK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

KCHILGNISGEFRHCWRVPA
FNSALIECMYDCCRMPGQTKPLCDSLATYTSICQSSGVAVLPWRTEDL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-MN

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCQRGCPLTCGDQPVPGGCG-SDCYESCVCDEGFVLSGEI
CIPLSS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVYQGIYHAPGDDFY--PGPECNSLCHCNKGGLVSCQPSYCGPHEVCKVIDG
ILR

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVGVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CHVSGASHYTTFDGRRFDFMGTC-VYVLAQTCWT-QPGLQPFTILQENV
VRGD-KQISVTKMITIEVANYTLQLEQNQWK-VKVNAVYMKMPVSLDGERV---QAF-LH
GTDV-VIKTK-FGLL-VSYDLKYSVRVTVPRNYYKHMCGLCGDYNNNPKNDFQKSD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAVSPGELGKSWEKTVPGSSCTPRPA--CKPGQD-CTP--KCY
PTLERKYSGNEF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTN------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
-----------------------------------------------PTGPLAACHKLLD
PQGPLQN---------------CVFDLCLGGGNLSILC-------------------NSI
HAYVSACQEAGGT--------------------VKPWRNQTF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
SPHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLDCSTITTPI--KCLK---
---------TCSEGCECDTDFLQSIT------ACVPM----EK

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCHHNGVYYEPEESVL
IE----------------------NCQQHCVCHPGTG----------------------M
VCQDHSCKPGEVCKPSRGV------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CINKDPCKGVTCRSQETCT-----------ERD
GKGVCTANYESK

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5603)

CWVWGDPHYHSFDGL----------------NTNFHG-TCSYQLAGT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPGISAEGLTPFNVVTKHESQSNPTVSNVKKV
TVTTYNTSITIHKKKIGRVQV-NGVLMALPVYLAEGRISVVHGGTKAVLETDFGLQVTYD
WTWRVQVTLPSSYYGAVCGLCGNMDKNPKND-----------------------------
---------------------R

ENSGT00760000118896_8_Linker_59_74 (5603, 5612)

VEEYEGPGF

PF08742 // ENSGT00760000118896_8_Domain_74 (5612, 5680)

CGPLSPDTVGPFASCHSHVPPESFFKGCV
LDLCLGGQVKDILCQALAAYAEACQAHGIKIQDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPRCPVS
CPPPTRHNPPTACDGPCVEGCQCDLGFVLSADQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYHEAGTEFWTDT
TCSKRCHCGP----GGDSLICKSASCGLGEECALLPSGEIGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTSI----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QILGDPRYITLDGHRFDFQGTCEYLLSAPCHAP-PPGIEYFNVTVANEHRGS--QAV-SY
-----TRSVTLHIYGLSLTLSTQWPRQLQV--------DGEMVTLPFQLQS-LLLVHLSG
T--GLIVHTTWGLSLVFDGDNFVRLRVPAAYAGTLCGLCGNYNKNSSDDLTAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPE--
------GWKVGGAPDCD-QCQLRPCPKPCTPEQQKHFDGPNA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIT
A-PKGPLAPCHSLVPP-TLFFEACLLDACQVQGHPGGLCPAIATYVIACQDAKAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYQLCGDSCPVSCPSLSAPKG-CET--ICREGCVCDSGFVLSGDTCV
PVSQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHNGRYYVLGDTFYPGPECERLCECGPGGQVTCRI-EICGIHEECRIEDGIRS
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6255)

HPKSSKLMLVLHG

PF00094 // ENSGT00760000118896_8_Domain_85 (6255, 6408)

IHYTTPDGLVY-DLY-------GSCSYILAQLCFLKPGEEEFSIVL
EKDLAGE-PQRVVVTVADQVVVLAKGP--QVTVDSEVVALPIV--AGSTYITAEGRNIFL
QTKRGLKLLFDGDDHILMSIPSAFRGRICGLCGNFNGNQSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GAVAPNVDAFGAA
WRVPGS--SLGCGEGCGPQGCPMCLAEKREAFEKNDA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKIRDPQGPFATCHKVLSHSEY
FHQCVFDLCTHNGDNAYLCRSLAAYTAACQAAGAAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTYSC----QGSCAALSGLTGCTSQCFEGCECDDHFLLSQGVCIPAQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCVHNG
QYVPVNSSLVSSDCIERCFCSPNNGLTCHEAGCPSGRVCEIQAGVRG

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWPAKG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6814)

CSLSV
GGNLTTFDGALNTISSP---GVYELSSRCPGLLK-NVPWYRLLADVQPCLDNDKIVSKVH
IFFQGGMVTVIPSKGA-WVN-GLRV----DLPATVLTSVSVRKMPDGSMFVHQKAGVQVW
LGKDGHLNVMVGEHYAAMLCGACGNFDGDRSNDVHKYQKKISMETWRAQDFSPCPN----
-

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-------------------------------------------------X----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSYGCPLSCGDLPVPEGCE-SACREGCVCDAGFVLSGDT
CVPVGQ

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCLHDDRYYPLGQTFY--PGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGG
SLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGHRFDFMGTC-VYVLAQTCGT-RPGLHRFAVLQENV
AWGN-GRVSVTRVITVQVANFTLRLEQRQWK-VTVNGVDMKLPVVLANGQI---RAS-QH
GSDV-VIETD-FGLR-VAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPN

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QAGNANEFGNSWEEVVSDSPCLPPPT--CPPGSEGCIPSEECP
PELEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY
VSACQVAGGHVEPWRNETF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------ME

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPQNSHYELCADTCSL
GCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQ

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1772)

GCYHNGAYYEPEQTVLIDNCRQ
QCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTK--DPCHGVTCRPQ-------E-T-C
--K-E-Q-G-G-Q-G-V-C-L-PN-Y-E-A-T-C

PF00094 // ENSGT00760000118896_8_Domain_31 (1835, 2340)

-WL-W-G-DPHYH-S-F-D-GR-K-F
-D-F--Q-G-T--C-N-Y-V-L-A-T-T-G-C-P-GV-S-T-Q-G-LTPF-T-V-T-T-K
-N-Q-N-R-G-N-PA-V-S--Y-V-R-V-V-T-V-A------------------------
--------------------------------A--L--G--T--N-I--S----I--H--
K----D--E--I--G--K--V---R--V--N--G--V--L--T--A--L-----------
------------------------------------------------------------
----PV-S-VA-D-GR-I-SV-TQ-GA-S-KA-LL-V-----------------------
-----------AD-F-G-LQ-VS-Y-DW-N-WR-V---------------D-V-TL-P-S
S-Y-HG-AV-CG-LCG-NM-DR-NP-N-ND-QV-FP-NG--------------------

ENSGT00760000118896_8_Linker_31_32 (2340, 2436)

T
-L-AP-SI-PI-WG-G-SW-R-A----------P-GW-DP-L-CWD-EC-RG-SCP-TCP
-EDR-LE-QY-EG-PG-FC-GP-LAP------GTG

PF08742 // ENSGT00760000118896_8_Domain_32 (2436, 2555)

-G-PF-TT-CH-AHV-P-PE-SF-F
K-GC-VL-DV-CM-GG---G---------D-RD-I-LC-KA-LA-SY-V-AA-C------
----------Q-A-AG-VV-I-ED-WR-AQ-VG-

ENSGT00760000118896_8_Linker_32_33 (2555, 2561)

CE-IT-

PF01826 // ENSGT00760000118896_8_Domain_33 (2561, 2635)

CPE-NS-HYE-VC-GPP-CP
A-SCPS-PAP-LTT-PA-VCEG-PCVE-GCQ-CDA-G-FVL-SA-DR-CV-PL-

ENSGT00760000118896_8_Linker_33_34 (2635, 2640)

NNG-C

PF12714 // ENSGT00760000118896_8_Domain_34 (2640, 2794)

G
C-WANG-TY-HE-AG-SEF-WA-DG-TC-S---------Q-WC-RC-GPG-GG-SLV-CT
P------AS-CG-----------------------------------LG-EV-CG-L-LP
-----------------------S-GQ-H-GC-

ENSGT00760000118896_8_Linker_34_23 (2794, 2804)

QP-VS-TA-E

PF00094 // ENSGT00760000118896_8_Domain_23 (2804, 3127)

CQ-AW-GD-PH-YV-TL
-DG------------------------HR-F-DF-QG-TC-EY-LL-S-AP-CH-GP---
---------P-L-GA-EN-F-TV-T-VA-NE-HR-GS-QA-V-S----------------
----Y-T-R-SV-TL-Q-IY-N-HS-LT-L-SA-RW-P-RK-LQ-V-DG-V-FV-T-L-P
-FQ-L-DS-L-LH-A-HL-SG-AD-VV-V-TT-TS-GL-S-LA-FD-GD-S-FV-RL-RV
-PA-AY-AG-SL-CGL-CG-NY-NQ-DP-A------------------------------
---D-D

ENSGT00760000118896_8_Linker_23_37 (3127, 3233)

L-KA-V------------------------------------------G-G-KP
A-GWQ-VG-GAQ-GCG-EC-V-SK-PC-PSP-CT-PE-QQE-SF-GGP-DA-

PF08742 // ENSGT00760000118896_8_Domain_37 (3233, 3432)

CGV-IS-A
T-DG-PL-A--------------PC-HG-LV-PP-AQ-YF-QG-CL-L------------
----------------------D-AC-QV-QG-HP-GG----------------------
-----LC-PA-VA-TY---VA-AC-QA-AG-AQ-LR-EW-R-RP----------------
--------DF-

ENSGT00760000118896_8_Linker_37_39 (3432, 3440)

CP-FQC--

PF01826 // ENSGT00760000118896_8_Domain_39 (3440, 3549)

-PA-HS-H-YE-----------------------LCG-DS-
CPG-SCPS-LS-APE-GCE-SAC-RE-GC-------------V-CD-AG-FV-LSG-DTC
-VP-VGQ-

ENSGT00760000118896_8_Linker_39_46 (3549, 3551)

CG

PF12714 // ENSGT00760000118896_8_Domain_46 (3551, 3680)

-CL-H-----------D-DR-YY-PL-GQ-TF-YP-GPGC-DS-LCR-CR
-E----------------G-GE-VSC-EPS-SC-GPH-ETC-RP-SG-G-----------
---------------S-LG

ENSGT00760000118896_8_Linker_46_27 (3680, 3692)

C-VA-VGS-TT-

PF00094 // ENSGT00760000118896_8_Domain_27 (3692, 4032)

CQ-AS-GD-P-------------------
------------H-YT-TF-DG-H-RF---------------------------------
-------------D---------------------------------FM-GT-C-VY-VL
---AQ-TC-GT-RP-G-LH-R-FA-V-LQ-EN-V-AW-----------G-NG-R-V-SV-
T-R-V-I----------TVQVANFTLRLE---------------QRQWKVTVNGVDMKLP
VVLANGQIRASQHGSDVVIET-----DFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYN
GDPKDDFQKPN

ENSGT00760000118896_8_Linker_27_55 (4032, 4107)

GSQAGNANE------FGNSWEEVVPDSPCLPPPTCPPG-----------
-SAGCIPSD--KCPPELEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_55 (4107, 4243)

CGL---------------LSSPTGPLSSCHKLVD
PQGPLKD---------------CIFDLCLGGGNLSILC-------------------SNI
HAYVSACQAAGGH--------------------VEPWRNETF

ENSGT00760000118896_8_Linker_55_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PQNSHYELCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSALSAPL--QCPDGCA
------------EGCQCDSGFLYNGQ------ACVPI----QQ

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEQTVL
IDN----------------------CRQQCTCHVGKV----------------------V
VCQEHSCKPGQVCQPSGGI------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCHGVTCRPQETCK-----------EQG
GQGVCLPNYEAT

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGR----------------KFDFQG-TCNYVLATTG
CP----GV--STQGLTPFTVTTKNQNRGNPAVSYVRV--------VTVAALGTNISIHKD
E-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------IGKVRV-NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYD
WNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5612)

TLAP-----SIPIWGGSWRAPGW
DPLCWDEC---RGSCPTCPEDRLEQYEGPGF

PF08742 // ENSGT00760000118896_8_Domain_74 (5612, 5680)

CGPLSSGTGGPFTTCHAHVPPESFFKGCV
LDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYEVCGPPCPAS
CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

NNGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADG
TCSQWCRCGP----GGGSLVCTPASCGLGEVCGLLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5990)

C
QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP-PLGAENFTVTVANEHRGS--QAV-SY
-----TRSVTLQIYNHSLTLSARWPRKLQV--------DGVFVALPFQLDS-LLHAHLSG
A--DVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD

ENSGT00760000118896_8_Linker_77_82 (5990, 6056)

LKAVGGKPA--
------GWQVGGAQGCG-ECVSKPCPSPCTPEQQESFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-TDGPLAPCHGLVPP-AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGDSCPVSCPSLSAPEG-CES--ACREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HATGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYITLDGRVY-DLH-------GSCSYVLAQVCHPKPGDEDFSIVL
EKNAAGD-LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVA--VGRVRVTAEGRNMVL
QTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GSAASSVETFGAA
WRAPG-S-SKGCGEGCGPQGCPVCLAEETAPYESNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLRNPQGPFATCQAVLSPSEY
FRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------H

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTRTC----QGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHNG
RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARN

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWATRG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6816)

CVLSV
GANLTTFDGARGATTSP---GVYELSSRCPGLQN-TIPWYRVVAEVQICHGKTEAVGQVH
IFFQDGMVTLTPNKGV-WVN-GLRV----DLPAEKLASVSVSRTPDGSLLVRQKAGVQVW
LGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPCYG----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------METGFHY--VG-QAGLELLTSSDLP-------------ASAS
QS---AGITTPWTLLILSFHRS-------LPSPAVLSPVEPSCEGV-QCAAGQRCQVVGG
KAECVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCSE--DETLPAFSVEAKNE
HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAV
VELV----FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLMPD

ENSGT00760000118896_8_Linker_4_8 (653, 713)

GAL-----
--------APDAVELASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGLLTKLD
GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC
RE----------------------------------------------------------
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-

-----------------------------------FLTAFLQNGGTTAPD--FRLYVSSA
QRAVKAGQQVTTLVTVEARGAAFRQELSLEPGRTECVRLPSSVELRGSAVRLGAVQVTSS
YLVSVLAVNARLRSLDTALVFPCQQLGTRYTVVTPVLQPQDRYKEFAVVAGPQATSVQLT
PPCAVSLGGLSYPAGRPLAVSLQPFEVVQVQSEIDLSGTLVVAKRPVAVLAGHSCLRAAD
DCELVCEQLLPAHLWGSSYAVPPFTTQVSAEEGSCDFVYV-AANAACLLSFWSGGTGGER
ALESGEVLRFPVDSRRPLVLRASAAVQVLFLAGSGARAGVSYDPWFSLIPPVDSYGCCYS
LTAQPGFSNLALLVAPGQGLEPGTVLLDKRPLTGLRWRPILWGKGSFSWAEVPYGTEGGG
SHQLETFGNQAIGVLSCGTSASAGFGTQAPLGETGFGPVGEAATD----------SVPEA
VLGSEPETAGT

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CWAAGLPYLSSFDGRSFAVPGACAYTLCRCIQGVPGAGLPAFHAWAGGA
-GGRL---PLRYVSLSVFGHTITAAKYEYGFVRVDQQRVRLPVTLARGRLRLTGTGTGTK
AGVGLGPQIAFCLVYDWQQSLSLKVAGGYRGQVGGLCGNFNGDPADDLSLTQ

ENSGT00760000118896_8_Linker_4_8 (653, 710)

GSVLVPNW
IAGTVLSSAASVRVFAQAWALEPASAPCHSRWGSSCILGS-----LDPT

PF08742 // ENSGT00760000118896_8_Domain_8 (710, 780)

STLCKLLENPQ
GPFQHCHRILDPKPFVLNCLASACVFTGYRPVVCQALETYAHACQREGATLGSWRLLANC
RE---------------------------CAGVLGAEGCLCLCV----------------
------------------------CPLPSLSE-------------PLSLPPPL-------
-----SVPSPDPFSVPGPRH---GPCL---------------------------------
------------SICLLSDLCPLRVVNGVWRNLPCQV-GGHVLVFRRGWDTVV

PF00094 // ENSGT00760000118896_8_Domain_12 (1014, 1057)

SCPFGLR
LAFDGGSHLMLALPRRYSGHVAGLCADYDGDPANDL

ENSGT00760000118896_8_Linker_12_13 (1057, 1120)

YPAIGDVPPSGLSGPASALALVRS
CRVGAA-QGCGEEVDGDAKD----------LTGHCKGAI

PF08742 // ENSGT00760000118896_8_Domain_13 (1120, 1189)

SGCHILVARDGPFRLCHGRLD
PRGYFQDCLRDACLMPRR--GACPILGGYAAACQEEGITIFPWRTRDF

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CR----------
-PP

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CLPHS---------HYELCGPGCPLTCGSLLGPSGCQAGRCREGCVCDAGFVLSGAR
CVPLRQCGCPLSGRYYEPGIRLPGIWGAPCRGPCVCRPGGQVFCPC---GAPPA------
---AALSGPGLCLISAGPYCRTFDGATLRLHGHC-SYTLAGTAPTRPPSLLPFSVLVENG
PFGAAL-----NRVALTAAGHSFVLDQGDWGYVTVSGIGPRQPWHVPGAGERAG--PRGQ
GREGDVLNPPSLGRPRCPASPVAQLAPTFPGS--GPFSGVCARVSA----VFCLPPSSPS
RLSPSLRLRVFGSTPQRPQIVPDDLGLSGPQPCPGPS--------CPPVG----------
EAVSAPFRG

PF08742 // ENSGT00760000118896_8_Domain_22 (1570, 1641)

PNSCGLLLAAQGPFAPCHGTLSPEPFFQSCLADVTRSRGNQHVLCRCLRSY
VAACQEAGAPVLPWRSSRMC

ENSGT00760000118896_8_Linker_22_24 (1641, 1665)

P---------------------MS

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPGHSHYSLCADPCPA
ACPGVRAIVRNPARCVEGCQCDPGFFPAAGACVPLKYCPCFHRGLYFAPGQTVLTNQCAS
ACSCQPGKGVMCVPHRCLPGQSCSVSSGVLGCLGPGD-----------------------
-------------------------LDDVLGS-----SWGWG---------------L--
--------GKGGCCL------------------P------S------------------E
---DVAGRRGVR------------------------------------------------
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----------------------------------------------------------DA
SSPGKWGPRGRTLG----------------------------------------------
--------------------------SL--------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TLPLSSPP-------------------------
-------------------------------TAFPLVPPA--------------------
-----------------------------PLTPPLA------------------------
-------------------------------------PGTGPA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPPYSRYVPCGPACPAT
CANPA---APAHCSQPCAPSCQCVPGRLLQAGRCVPSE-QCGCLL-----RPDKAFWTEG
-CGQRCRCPADGDPGAAGVQCWPARCR--GRCEEVSGGRHRCRPIRLGS----GPQHVT

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5982)

C
TASGDFRFQTFGGARYHFPGSCVYRLAGPCGRGGRSGLDPFYLDMATLIR----------
-PLGCSKSLTLRACGLRLDMSPVDPNLLRV--------DGVLESLPFFHGR-CLRAYTSG
G--QLCLDTASGLSLTYDWDSLVRLSVPRALARSLCGLCGD

ENSGT00760000118896_8_Linker_77_82 (5982, 6038)

MARG----------IPTSH
LPGLAHSWKVAEVPGCGPSCG-PYCPPPCLATQRGRY

PF08742 // ENSGT00760000118896_8_Domain_82 (6038, 6126)

RGPSY-------------CGLMG
A-SAGPLAPCHRTLNP-TPFMEDCLEEVCRHRGCRPALCRALTAYVAACQAQGVRLRPWR
TPSLC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PRR

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPPHSHYELCGPYCPETCGAPKGPRG-CQPGVRCREGCVCDAGFVLSGASCV
PRSRCGCLHAGRYHALGTAWYPGPSCERRCRCRPGRTVSCRPG-RCRSHEACAIRGGIRG
CFPDGQAS

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6406)

CFLAGPTHGLTFDGRVLGGLA-------GPCAYLLARAT--GSGLEPFGLQV
EKDEAGP--RQIHLNLYGRRLALDRGAPGTVVVDGERCRLPLVLPGGRLWVTREGRGVAV
QAACGLRLFYDSERHLRLTLPSTYRGRLAGLCGNFNGDGGPDDFG

ENSGT00760000118896_8_Linker_85_88 (6406, 6455)

PSG----SLEAFVAT
WALPGPG------RCAPTGPCPPCPRGLDAAFSG

PF08742 // ENSGT00760000118896_8_Domain_88 (6455, 6527)

PSACGLLRLPRGPFGRCHSLVRPDPF
YGFCVRDMCQARRGRRGLCDSLTAYTEACQEAGALVQP-WRSPRLC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------R

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPPR
SHYSVCARTC----DLGCAPLFGPRRCSPHCVEGCECDPGFVSDGAACVPQERCGCFRLG
RY----------------------------------------------------------
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-

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----------------------KGRYQSL

PF08742 // ENSGT00760000118896_8_Domain_74 (5610, 5681)

-LCRLLS-ARDEPFQACDEPAEARVHVETVS
TTSAPPEARGRMLCEVLGSYAQQCQRHGLPVQPWRHLVDC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

EPA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPPHSHYELCGSSCPSS
CAEPAL---PDSCPTPCQEGCQCDAGFVLSGTDCVSPS-QCGCSAGGRYHPAGEAFWAGE
RCERFCRCEA----SSHAVHCSPASCGPGQRCGNR-RGIFGCHPLSP----------GTC
HAAGHSGIITFDGRAVELPSTCASVFAESCGAPGSLPFFRVELGLVGVWPSGYRVAWQAR
IPCQWSAWLPLPANAHPMH----WALYVCVSLMTNNDHVGDWVLITY---C-HVTMVFSG
R

PF00094 // ENSGT00760000118896_8_Domain_81 (5942, 5995)

SEYLLLNVGTGLQVHFNGRHTLLVRVGPEHRGRLCGLCGNFNGDPGDDKVLPS

ENSGT00760000118896_8_Linker_81_82 (5995, 6068)

GAPARS
DADFGNAWQTQDSQPGWRHTW--------GGNRGARKAGPGRAGVRAGQPHSLRFCVPGE
R-VPGPP

PF08742 // ENSGT00760000118896_8_Domain_82 (6068, 6125)

AACSRDMDPRVHVEN-CVHDLCATGGSRDTLCAVLGSYAQECQRRGLPLQPWR
HLVACVLPCLLRAWAEMCGTAGASS-----------------------------------
------------------------------------------------------------
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-

------------------------------------------------------------
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-----------------------------------------MP-----------------
-----AQADT-SDSLSLS-------LSPPLPSPARLSSAATACEGV-QC-----------
--------------

PF00094 // ENSGT00760000118896_8_Domain_4 (495, 652)

AGDPHYTTFDGRRYDMMGTCSYSMAELCGT--DETLPAFSVEAKNE
HRGSRRVSYVGLVTVRAYSHSVSLARGEVGFARIDNQRSRLPASLSEGRLRVYQSGTRAM
VDLD----FGLVVTYDWDCQLTLSLPTRFQNEVCGLCGNYNGDPADDFLMP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DWEL-----
--------APDAMEFASSWKLDDGDYLCEDGCQNNCPSCTPGQAQHYEGDQL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTQPG
GPFAKCHEALDPRPFLEECVYDLCVTSGERLSLCRGLSAYAQACLELGVSVGDWRSQANC
R-----------------------------------------------------------
------------------------------------------------------------
--D

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1059)

CQASGDPHYVSFDGRRFDFMGTCTYLLVGSCGQD--AALPAFRVLVENEHRGSQTVS
YTRAVRVEARGVKVAVRREHPGRVLVDGVLQYLPFQAADGQVHVFRQGSDAVVRTDSGLM
VTYNWDSRVTVKVPGSYAGALCGLCGNFNGDPSDDLAL

ENSGT00760000118896_8_Linker_11_13 (1059, 1121)

QGGGQAA-------NALAFGNS
WQAETRP-GCGAADPGDCPK-------LDSLVAQQLQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPEGPFRECHNTLD
PQGAVRDCVYDHCLLPGQSGPLCDALATYAAACQATGATVHPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LN

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEVCSHGCPLSCGDLPVPGGCG-SECHEGCVCDEGFVLSGES
CMPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYHPPGQTFY--PGPGCGSLCHCQEGGLVSCEPSACGPHEVCQPSNG
ILG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGRRFDFMGTC-VYVLAQTCGT-RPGLHQFAVLQENV
AWGN-GKVSVTRVITVQVANFTLRLEQSQWK-VTVNGVDMKLPVVLAEGRI---RAF-QH
GSDA-VIETD-FGLR-VAYDLVYYVRVTVPGNYHSVMCGLCGNYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GL--
-----------------QTGSANEFGNAWETPVPGSPCLPPPT--CPPGSEGCNPDLECP
PELEDKYHKEQF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLTSPTGPLASCHKVIDPQGPLQDCVFDLCLGGGNLSILCSNIHAY
VSACQAAGGHVEPWRTDSF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------MP

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPPHSHYELCADTCSL
SCSALSAPPQCPDGCAEGCQCDPGFLNDGQACVPIQE

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1772)

GCYHNGVYYEPEQTVLIDNCRQ
QCTCHAGKGMVCQDHSCKPEQVCQPSGGVLSCITK--DPCHGVTCRPQ-------E-T-C
--K-D-Q-G-G-Q-G-V-C-V-PN-Y-E-A-T-C

PF00094 // ENSGT00760000118896_8_Domain_23 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GR-D-F
-D-F--Q-G-T--C-N-Y-V-L-A-A-A-G-C-P-GV-S-A-Q-G-LTPF-T-V-A-T-K
-N-E-N-R-G-N-PA-V-S--Y-V-R-L-V-T-V-T------------------------
--------------------------------A--L--G--I--N-I--S----I--H--
K----G--E--I--G--K--V---R--V--N--S--------------------------
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----------V--------------L----------------------------------
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--------------------------TALPVSVASGQLSVTQGASKALLAAAFGLQVSYD
WDWRVEVTLPSSYHGAVCGLCGNMDRNPNNDQLFPNG

PF00094 // ENSGT00760000118896_8_Domain_27 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GR-D-F-D-F--Q-G-T--C-N-Y-V-L-A-A-A-G-C-P-GV-S-A-Q-G-LTPF-T-V-A-T-K-N-E-N-R-G-N-PA-V-S--Y-V-R-L-V-T-V-T--------------------------------------------------------A--L--G--I--N-I--S----I--H--K----G--E--I--G--K--V---R--V--N--S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V--------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TALPVSVASGQLSVTQGASKALLAAAFGLQVSYDWDWRVEVTLPSSYHGAVCGLCGNMDRNPNNDQLFPNG

ENSGT00760000118896_8_Linker_27_74 (5558, 5620)

TLAP-----SIPIWGGSWRVPGW
DPLCWDEC---QGSCPTCPEDQLGEYEGPGFCGPLAPGT

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

GGPFAACHAHVPPDSFFKGCV
LDVCLGGGAHDILCQALASYAAACQAAGIVIKDWRVQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYQLCGPPCPAS
CPSPAPPTTPALCEGPCVEGCQCDKGFVLSANRCVPV

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADA
TCSQRCRCGP----GGGSLVCTPASCGQGEECALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

HPIST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5991)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCHGP-PKGAENFTVTVANEHRGS--QAV-SY
-----TRSVTLHIYNHSLTLSARWPRQLQV--------DGELVALPFQLDS-RLRAHLSG
A--DVVVTTTSGLSLAFDGNSFVRLRVPAAYAGALCGLCGNYNQDPADDL

ENSGT00760000118896_8_Linker_77_82 (5991, 6056)

TAVGGNPG--
------DWQVGGAPGCG-ECVPGPCPQPCTPQQQEAFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIL
A-TDGPLAPCHDLVPP-AQYFQA-------SQGHPGGLCPAVAAYVVACQAAGAQLGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPVHSHYELCGDSCPVSCPSLSAPEG-CEP--ACREGCVCDAGFVLSSDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYPLGETFYPGPECERRCECGPSGHVSCQEGTACGPYEECRLENGIQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLASGGIHYITLDGRVY-DLH-------GSCSYVLTKVCHPKPGDEDFAIVL
EKDKAGD-SQRLLVTVADQVVSLARGP--QVTVDGEAVALPVS--VDRVQVTAEGRNMVL
QTTKGLRLLFDGDAHILMSIPSPFRGRLCGLCGNFNGNWSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GVVAPSVEAFAAR
WRAPG-S-SQGCGEGCGPHGCPVCSAEETAPYESNQA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLRDPQGPFATCHAALSPSEY
FRQCVYDLCAQKGDTAFLCRSLAAYTAACQAAGMAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTRTC----QGSCAALSGLTGCTTRCFEGCECDNLFLFSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHGG
RYLPVNSSLLTSDCNEHCSCSSSTGLTCQAAGCPPGHVCEVRAETRD

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWASRG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6819)

CSLSV
GANLTTFDGARSAVSSP---GIYELSSRCPGVRK-TIPWYRVIANVQPCPGKVEAVGQVH
IFFQDGMVTVTPSKGV-WVN-GLRV----DLPAEVLTSVSVSRTPDGSMLVRQKAGVLVW
LGTDGQLAVMVSDDHAGMLCGACGNFDGDQTNDGHNSQGQTVMEKWRAQDFSPW------
-

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-------MGSLRSWWTLWAGATLLW--------GLVSSEEPSCEGV-TCAAGQQCQVVDG
KAVCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGL--DETLPAFSVEAKNE
HRGSLLVSYVGLVTVRAYNHDVTLARGEVGFVRINNQRSGLPVSLSKDRLRVYQRGTRAV
VELD----FGLVVTYDWDAQLTVSLPAKFQDQVCGLCGNYNGNPADDFLTP

ENSGT00760000118896_8_Linker_4_8 (652, 707)

DWVQ-----
--------ASDALEFANSWKLDDGDPLCDDGCQGNCPSCTAAQTEQ

PF08742 // ENSGT00760000118896_8_Domain_8 (707, 781)

YKGDHLCGMLTLAE
GPFAPCHEVLEPQSFLDDCVYDLCVTGGERLSLCRLLSTYAQACQELGVSVTDWRSSASC

ENSGT00760000118896_8_Linker_8_9 (781, 784)

PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSSYELCGPACPATCNSVAAPSNCSERPCVEGCVCLSGFVASGGACIPESSCGC
TFEGLLLAPGQQVWADTLCKQSCTCDGTT-HQVSCQDTQGCPEGERCRVENNLLGCYPES
FGS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1061)

CQASGDPHYVSFDGRRFDFMGTCTYLLAGSCGQN--TALPSFSVLVENEHRGSQTVS
YTSAVQLKVYGVEVAVNRKYPGQVLVDGVLKNLPFQAADGRVQLFRQGNNAVVRTDFGLT
VTYDWDALVTVKVPSSYAKALCGLCGNFNGDPSDDLALRD

ENSGT00760000118896_8_Linker_11_13 (1061, 1117)

GNQAA-------NALDFGNS
WQEGTRP-GCGASDAGDCPT-------LDSQVTQQL

PF08742 // ENSGT00760000118896_8_Domain_13 (1117, 1190)

QSKKECGILADPEGPFRDCHKKLD
PQGALRDCVYDLCLLPGQSELLCDALATYAAECQAAGATVEPWRSEELC

ENSGT00760000118896_8_Linker_13_14 (1190, 1204)

P----------
-RS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPEHS---------HYESCARGCPLSCGDLPVSGGCG-SECYESCVCDEGFVLSGES
CVPLASCGCVYQGSYYQPGQTFH--PGPGCDSLCHCQEGGLVSCEDSSCGPQEECQLSGG
VLGCVVVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1498)

CQASGDPHYVTFDGSRFDFMGTC-VYVLAQTCGT-PPGRPQFTVLQENE
AWGN-GQVSVTKAITVLVGNHTIRLEQSQQK-VTVDGVDLKPPVELDKGEI---RIN-QH
GSDV-VIETD-FGLR-VVYDLMYYVRVTVPGNYYQQMCGLCGDYNGKAEDDFQKRNG

ENSGT00760000118896_8_Linker_19_22 (1498, 1567)

S--
-----------------QAANPNDFGNSWEEAVPGSPCLPPPE--CDSD-----ADCKCT
PELEEQ

PF08742 // ENSGT00760000118896_8_Domain_22 (1567, 1643)

YKKEEFCGLLTSSTGPLSSCHKLLDPQNSLQDCVFDLCLGGGNESILCGHIHAY
VSACQAAGGQVQPWRNEKFC--

ENSGT00760000118896_8_Linker_22_24 (1643, 1665)

P-------------------ME

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPPHSHYELCADTCSL
GCSALSGSVQCPDGCAEGCQCDPDFYYNGEACVPIQQCGCYHNGVYYEPEQTVLTDNCQQ
QCVCHSGTGVTCQEHSCKPGQVCEPSGGVLSCVSK-------------------------
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--------------------------DPCQGVTCRPQETCKEQDGQGVCVPNYNAT

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYNTFDGRAFDFQGTCNYILVQV-GCPGVDAEGLTPFTITTKNENRGNPTVSYVKEV
TVSVLGTNISIHKGETGKVRV-NGVLTTLPVSAAGGRIYVSHGVWKAVLVTDFGLQVTYD
WDNRVEVILPSSYHGAVCGLCGNLDGDPNNDQVFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5607)

TAAP-----SIPAWGGSWRAPGW
DPLCWDEC---QGSCPTCSEDLLEKY

PF08742 // ENSGT00760000118896_8_Domain_74 (5607, 5680)

QGPGFCGPLVPGTESPFADCLAHVSPDSYFQGCV
LDVCLSGGAQDILCQALASYAAACQAAGVAIQEWREQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CGVS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYELCGSPCPAS
CPAPESTKTSALCEGSCVEGCQCDTGFVLSAGRCVPLEGGCGCWANSTYYETGSEFWTDA
TCSQRCRCGA----EGGSLVCTPASCAKGEACALLSSGQYGCQPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCSEP-PAGTENFTVTVVNEHRGS--QAV-SY
-----TRSVTLYIYDHRLTLSARWPRQLQV--------DGEFVTLPFQLDS-RLNAYVSS
A--DVVVTTAAGISLSFDGDSFVRLRVPAAYAGALCGLCGDYNENSADDLAAVN

ENSGT00760000118896_8_Linker_77_82 (5995, 6040)

GKPE--
------GWQVGGEPGCE-KCEPEPCPEPCTPEEQEPFGG

PF08742 // ENSGT00760000118896_8_Domain_82 (6040, 6126)

PDA-------------CGVIM
S-RKGPLGPCHCIVPP-EQYFQACLLDACQAQGHPGGFCPAVAAYVAACQAAGAEIGEWR
LPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

SIQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYELCGNSCPVSCPSLSAPEG-CEP--TCREGCYCDAGYVLSGDTCV
PLGQCGCLHEGRYYPLGAAFYPGPECERRCECGPGGQVSCKEGAACGPYEECRLEDGVQA
CHPKGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CLADGGIHYLTLDGRVY-DLH-------GSCSYILAQVCDPQPGDEDFTIVL
EKNAAGE-PQRVLVTVAGQVVGLARGP--EVTIDGEVVDLPVA--VGHVRVTSEGRNLIL
QTTEGLRLLFDGDAHVLISIPSPFHGRLCGLCGNFNGNWSDDFELPDG

ENSGT00760000118896_8_Linker_85_88 (6409, 6453)

SVAPSVEDFGAA
WRAPG-S-PQDCTEGCGAQGCPVCRAEETAPY

PF08742 // ENSGT00760000118896_8_Domain_88 (6453, 6527)

ESSELCGRLLDPSGPWAACHEVLSPSEY
FRQCVYDLCAQKGDQAFLCRSLAAYTADCQAAGVAVKP-WRTDSFC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAN
SHYSVCTYSC----QGSCTALSGLTGCTSHCFEGCECDDRFLLAQGVCVPSQECGCTYNG
RYLPVNSSLLSSDCNELCYCSPDADLQCYEASCKAGSVCEVQNGVRVCQASGA-Q

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6813)

CTLSA
GSNLTTFDGALSAFNSS---GVYELSFRCPGLQ---TPWYRVVAAIQPCAGTAETVGQLH
VFFEDGIVTVTRDGGV-WVN-GRQV----DLPAEVLTSVSVTRNSDNSILVHQKDGLWVW
LGADGQLTVTVDSGRAGQLCGACGNFDGDPTND------KSVTESWTAPDLSPW------
-

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------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSPWNWWAL----------W-------
--------------------------AGATLLWALLTPAEASCQGI-HCASGQRCQMVSG
KARCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGS--DETLPAFSVEAKNE
HRGSRQVSYVGLVTVYAYSHSVSLVRGEIGFVRIDNQRSRLPASLSEGRLRVHQSGTRGV
IEMD----FGLVVTYDWDGQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DLDQ-----
--------APNALEFANSWKLDDGDYLCDDGCHNSCPSCTPGQTQHYKGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLST
GPFSACHEFLDPKPFLDDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRLPAS

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSCYDPCSPACPPSCNSEAAPTNCSSRPCVEGCVCLPGFVASGGDCVPVSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
IYQGRPLAPGQEVFDDDQCRRRCTCDGAT-QQVTCRDTTGCPSGERCNVQNGLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1059)

CQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQN--AALPAFKVLVENEHRGSQTVS
YTRAVRVVAHGVEVAVRRENPGRVLIDGVLQYLPFQAAGGKIQVHRQGNDAIVSTDFGLT
VTYNWDAHVTAKVPSSYAKAVCGLCGNFNGNPDDDLAL

ENSGT00760000118896_8_Linker_11_13 (1059, 1121)

KGGGQAS-------NVLDFGNS
WQEEIIP-GCGATEPGDCPQ-------LDSLVTQQVEGKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPEGPFRECHKLLN
PQGAIRDCVYDLCLLPGQSGPLCDALAAYAAACQAAGGTVHPWRSGKL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPNS---------HYEQCSYGCPLSCGDLPVQGGCG-SECREGCVCNEGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGAYHAPGETFY--PGPGCDSLCHCEEGGLVSCEPSSCGPQEACQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGTTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYITFDGRRFDFMGTC-VYVLAQTCGN-RPGLHQFTVLQENE
AWGN-GKVSVTKVITVLVANYTLRLEQNQWK-VKVNGVDMKLPVVLDGGKI---RVS-QH
GSDV-VIETD-FGLR-VAFDLVYYVRVTIPGNYYKQMCGLCGDYNGDPQDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QTTDPSDFGNSWEEAVPDSPCAPV-P--PCT-GDDCDT--ECS
PELQDKYHGEQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTS------------------------------------------
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-----------------------------------------------PSGPLAACHKLLD
PQGPLQD---------------CVFDLCLGGGNQSILC-------------------NII
HAYVSACQAAGGQ--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCWALNTPQ--QCPE---
---------GCAEGCECDSGFLYNGK------ACVPI----EQ

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEESVL
IE----------------------NCQQHCVCQPGKG----------------------M
MCQDHSCKPGQVCEPSGGI------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCHGITCRPQETCK-----------VQG
GEGVCVPNYNST

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYNSFDGW----------------SFDFQG-TCNYLLAGT-
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------LCPGVDAEGLTPFTVTTKNENRGSPAVSYVREV
TVTTLNTNISIHKNEIGKVRV-NGVLMALPVYLAGGRISVINGGSKAVLETNFGLQVTYD
WNWRVEVTLPSSYHGAVCGLCGNMDKNHQNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5620)

TMAP-----SIPTWGGSWQVPGW
DPLCWHEC---QGSCPTCPEDRVEEYEGPGFCGPLAPGT

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

GSPFTSCHAHVPPESFFKGCV
LDVCLGGGSKDILCQALAAYAAACQAAGIKIEDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPARHTAPAACDGPCVEGCQCDEGFVLSADQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYYEAGTEFWADT
TCSKRCHCGP----GGDSLVCKPASCGLGEECALLPSGEIGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTSI----------TE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHEP-PTGTEYFNVTVANEHRGS--QAV-SY
-----TRSVTLWIYGLSLTLSAQWPRKLQV--------NGEFVALPFHLDQ-KLSVYISG
A--DVVVNTASGLSLAFDGDSFVRLRVPAAYAGTLCGLCGNYNKNPSDDLTAVDGKPE--
------GWKVGGAPGS--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GAAVKP-WRTDSVCPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTRSC----QGSCAALSGLTGCTTRCFEGCECDDHFLLSHGVCIPAQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCVHNG
QYMPVNSSLMSSDCSERCFCSPNTGLTCHEAGCPSGHVCEIQAGVREC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QAARG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6819)

CSISV
GANLTTFDGAHNAISSP---GVYELSSRCPGLLK-NVPWYRVLADVQPCHENDKIVSKVH
IFFQDGMVTVIPSKGA-WVN-GLRV----DLPATVLTSVSVRRMPDGSMLVHQKAGVTVW
LRKDGLLDVMVGDDLAAMLCGACGNFDGDQTNDAHGSQGKTPIEKWRAQDFSPCSN----
-

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----------------------------------------------------------LL
GP---EEMGAQRSWWPIWAGVSFLL--------VPLPTADASCSGV-KCGPQERCQMVAG
KPTCSAASTAT

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CWAQGDPHYTTFDGR---------YTLSEFCGF--DDTLPSFSVETKNE
HRNSKKVSYVGLVTVSAYSQVVSLARGEHGFARINNQKSRLPVSLHDGKLRVFQSGTQGV
IEMD----FGLRVTYNWDCRLSLTLPSRFQNEVCGLCGNYNGNPADDFLKQD

ENSGT00760000118896_8_Linker_4_8 (653, 708)

ETL-----
--------ATDAVEFAESWKLDDGDQFCSNDCQGGCPSCTPGQTQHY

PF08742 // ENSGT00760000118896_8_Domain_8 (708, 780)

EGDRVCGMLSLAT
GPFALCHDILDPQSFLKDCVYDLCASNGDRPSLCRALDSYATACREQGVTVQDWRTAAGC
RE----------------------------------------------------------
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-

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--TQTQESLAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCSE--DDTLPAFSVEAKNE
HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLIDSQRSRLPVSLSEGRLRVYQSGPRAV
VELV----FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLMPD

ENSGT00760000118896_8_Linker_4_8 (653, 713)

GDQ-----
--------APDPVEFASSWKLDDGDYLCEDGCQNNCPTCTPGQAQHYEGDQL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTKLD
GPFAVCHDTLDPRLFLEQCVYDLCVVGGDRPSLCRGLSAYAQACLELGISVGDWRSPANC
RE----------------------------------------------------------
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--

PF08742 // ENSGT00760000118896_8_Domain_13 (1143, 1190)

GALRDCVYDRCLLPGQSGPLCEALATYAAACQAAGATVHPWRTEKFC

ENSGT00760000118896_8_Linker_13_14 (1190, 1204)

P----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPTHS---------HYEACSYGCPLSCGDLPVPGGCG-FDCYEGCVCDEGFALSGES
CVPLPSCGCVYQGIYHPPGQTFY--PGPGCDSLCQCQEGGLVSCEPSACGPQEACQPSGG
ILGCVVVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1498)

CQASGDPHYTTFDGRRFDFMGTC-VYVLSQTHQT-RPGLQHFTVLQENV
AWGN-GKVSVTRVITVQVANFTLRLEQNKWK-VTVNGVDMRLPVVLAQGQV---RVT-QH
GSDV-VIDTD-FGLR-VAYNLVYNVRVTVPGNYYQQLHGLCGNYNGDSKDDFQKPDG

ENSGT00760000118896_8_Linker_19_22 (1498, 1566)

S--
-----------------QAGNSNEFGNSWEEAVPGSPCLPPPT--CKPGE-NCNPDLECP
PELEE

PF08742 // ENSGT00760000118896_8_Domain_22 (1566, 1643)

KYKQEKFCGLLTSPTGPLAACHKLVDPQGPLKDCVFDLCLGGGNESILCSDIHAY
VSACQAAGGSVDPWRTESFC--

ENSGT00760000118896_8_Linker_22_24 (1643, 1665)

P-------------------ME

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPPNSHYEVCADTCSL
GCSALSAPPHCPESCAEGCQCDPGFLSNGQGCVPIQQ

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF02345 // ENSGT00760000118896_8_Domain_25 (1719, 1773)

GCFHNGVYYEPNEVILINNCQQ
QCVCHAGEGVVCQAHSCQPGQVCETSGGVLSCITK--DPCHGVTCRPQ-------E-T-C
--Q-E-K-A-G-Q-A-V-C-V-PN-Y-E-A-T-C

PF00094 // ENSGT00760000118896_8_Domain_23 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GW-D-F
-D-F--Q-G-T--C-N-Y-V-L-A-A-A-G-P-E-GG-S-S-Q-D-LTPF-T-V-T-T-K
-N-E-N-R-G-N-PA-V-G--L-D-S-S-H-V-C-S------------------------
--------------------------------A--Y--Q--M--T-Y--N----------
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------RSLVMMEALAAASHV-NGVLTALPVSLAGGRISVTQGPSKALLVTDFGLQVSYD
WDWRVEVTLPSSYHGEVFGLCGNMDRNISNDRVFPNG

PF00094 // ENSGT00760000118896_8_Domain_27 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GW-D-F-D-F--Q-G-T--C-N-Y-V-L-A-A-A-G-P-E-GG-S-S-Q-D-LTPF-T-V-T-T-K-N-E-N-R-G-N-PA-V-G--L-D-S-S-H-V-C-S--------------------------------------------------------A--Y--Q--M--T-Y--N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSLVMMEALAAASHV-NGVLTALPVSLAGGRISVTQGPSKALLVTDFGLQVSYDWDWRVEVTLPSSYHGEVFGLCGNMDRNISNDRVFPNG

ENSGT00760000118896_8_Linker_27_74 (5558, 5605)

TLAP-----SIPVWGGSWHAPGW
DPLCWDEC---QGNCPTCPEDRLE

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

EYKGPGFCGPLAPGAGGPFAACHAHVAPDSFFKGCV
LDVCLGGGTHDILCQALAAYAAACQAAGIAIKDWREQAGC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

EIA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPENSHYELCGPACPDS
CPSPTPPTTPKPCDGPCAEGCQCNSGFVWSADRCVPLDGG

ENSGT00760000118896_8_Linker_75_76 (5741, 5742)

C

PF02345 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADA
TCSQRCHCGP----GGGSLVCKPAKCGVGEQCALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5996)

C
QAWGDPHYVTLDGHRYDFQGNCEYLLSAPCNAL-PTGAENFTVTVVNEHRGS--QAV-SY
-----TRSVTLHIYEHSLTLSAQWPQQLQV--------DGKLVALPYQLDS-RLSAYVSG
A--DVVVTTAAGLSLAFDGNSFVRLRVPAPYAGALCGLCGNYNQDPADDLKAVDG

ENSGT00760000118896_8_Linker_77_82 (5996, 6036)

DPS--
------GWQVGGEAGCG-ECVPGPCPPQCTTEQQG

PF08742 // ENSGT00760000118896_8_Domain_82 (6036, 6126)

AFAGPDA-------------CGVIS
A-ADGPLAPCHSLVPP-EQYFQACLLDACQAQGHPGGLCPAVAAYVAVCQAAGAQLGEWR
RPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYKLCGDSCPVSCPSLSAPEG-CVQ--SCREGCVCDAGFVLSGDTCV
PVGQCGCLHEGLYYPLGESFYPGPECERRCECGSGGQVTCQEGSACRPYEECRVEDGVQA
CHPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CVANGGLHYITLDGRVY-DLH-------GSCSYVLAKVCNPQPEDEDFSIVL
EKDAAGD-LQQLVVTVAGQVVTLARGP--KVTIDGEAVALPVA--VGRVRVTAEGRNTIL
QTTKALRLLFDGDAHVLISIPSPFRGRVCGLCGNFNGNWTDDFVLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6451)

AEAPSVDAFGAA
WRAPS-S-SQGCDEGCGASGCPVCSAEETA

PF08742 // ENSGT00760000118896_8_Domain_88 (6451, 6527)

PYESNQACGQIRDPQGPFADCHAVLNPSEY
FRQCVYDLCFHKGSTTFLCSSLAAYTAACQAVGGTVKS-WRTDSFC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSTCTRSC----QGSCAALSGLTGCTSRCFEGCECDDRFLLSHGTCVPVQN

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF02345 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCAHNG
HYLPVNSSLLSSDCRQRCSCSPSTGLTCGAVSCGSDRVCEVQAGARNC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

WAPQG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6815)

CSLSV
DANLTTFDGSHGAFRSQ---GIYELSSLCPGLPD-TIPWFRVVAVVQACQGKVGPVNQVH
IFFEDGLVILSSENGVWWVN-GIHV----ALPAELSASVSMQKNPDGSVSVNQKAGVQVQ
LGIKGQLTVMVSEEHSGKLCGVCGNFDGDQTNDGH-------------------------
-

MGFLWSWWTLWAGATLLWGLTQEASVDPSNAEGEEFLTAFLQNYQPGYVKGNLYLLITSL
SDS-------SASVTILSQADGTSQNVPVKPGQSVMVNIGTKAEMIGSNIFQHAVLVRSD
RNISVQAINTKPNTEDLTLLRPVSTLGTKYFVFTPPSASAKNVKEFAVVAGAKGASISVQ
LKAAVTFQGNFYPGGSVLTVTLKPYQVAQVQSTADLSGSKVTASSPVVVLSGHSCAQKHT
SCNHVVEQLLPTSAWGTHYVVP-PLAS----QTRFDVVYA-VASQPTKLTYNHGNIIGSR
GLQEGDVIEFEVRPSWPLFLSADVGIQVLLFGTGGTKDRVTYDPYLVLIPDVEAYCPAYV
VNNFPGSKGVALVVAQTKAADKLTI--DG-HGLGTRLTWVTVPGSEFSYAEVDLNSTNMI
HM---TMANTSFGLLTFWLTQSGGYGTAAACGQTLLSAEKPSCEGV-QCPPSQICQVVDG
HAKCMPGSVAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCSYTMVELNSE--DQTLPAFSVEAKNE
HRGSRRVSYVGFVTVHAYSHSVSLARGEVGFARIDNQRSRLPASLAEGSLRVYQSGRRAI
VELD----FGLVVSYDWDCQLALSLPTRFQGQVYGLCGNYNGDATDDFLTPDG

ENSGT00760000118896_8_Linker_4_8 (654, 706)

EQ-----
--------APNVLEFANSWKLDDGDFLCEDSCQDSCPSCTPGQAQ

PF08742 // ENSGT00760000118896_8_Domain_8 (706, 781)

HYEGDRLCGMLTKPN
GPFAACHDTLSPWPFLKECVYDLCVLNGDRSSLCRGLSVYAQACLELGVSIKDWRSPANC

ENSGT00760000118896_8_Linker_8_9 (781, 784)

PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYELCDPACPASCNPTAAPANCSGRPCVESCACLPSFVASGGACVAASS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF02345 // ENSGT00760000118896_8_Domain_10 (839, 897)

GC
IYEGRPLAPGQQVWADERCRRRCTCNGAT-QEVSCSDTQGCPAGERCRVQNGLLGC

ENSGT00760000118896_8_Linker_10_11 (897, 904)

YPDR
FGS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1062)

CQASGDPHYVSFDGRRFDFMGTCTYLLAGSCGQN--AALPAFRVLVENEHRGSQTVS
YTRAVRLEARGVKVAVRREHPGQVLVDGILQYLPFQAADGQVQVFRQGQDVVIRTDFGLT
VTYDWNARVTAKVPGSYAGALCGLCGNFNGNPDDDLALRGG

ENSGT00760000118896_8_Linker_11_13 (1062, 1115)

GQAD-------NALDFGKS
WQEETRP-GCEATKPGDCPK-------LESLVAQ

PF08742 // ENSGT00760000118896_8_Domain_13 (1115, 1190)

QLQSKKECGILADPKGPFGECHHKLD
PQGAVRDCVYDLCLLPGQSGPLCDALAAYAAACQATGATVHPWRSEKLC

ENSGT00760000118896_8_Linker_13_14 (1190, 1204)

P----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCSRGCPLSCGDLPVPGGCG-SDCHEGCVCDEGFALNGES
CVPLSSCGCLYQGIYHPPGQTFY--PGPGCDSLCHCQEGGLVSCKPSNCGPHEACQPSGG
ILGCVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1498)

CQASGDPHYTTFDGRRFDFMGTC-VYVLAQTCGT-RPGLDQFAVLQENV
EWNN-RKVSVTRVVTVQVANFTLRLEQNQWK-IKVNGVDMKLPVVLAEGRV---RAS-QH
GSDI-VIQTD-FGLR-VAYDLMYNVRVTVPGNYYQQLCGLCGNYNGDPKDDFQKPDG

ENSGT00760000118896_8_Linker_19_22 (1498, 1566)

S--
-----------------QAGSPNEFGNSWEEAVPGSPCLRPPT--CKPGED-C-NPPECG
PELQN

PF08742 // ENSGT00760000118896_8_Domain_22 (1566, 1643)

KYQQEQFCGLLTSPTGPLAACHKLLDPQGPLHDCVFDLCVGDGSQNILCSNIHAY
VSACQALGGHVKPWRNESFC--

ENSGT00760000118896_8_Linker_22_24 (1643, 1665)

P-------------------MK

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPSNSHYELCADTCSL
SCSALSAPPQCPDNCAEGCQCDPGFLSDGQACVPIQK

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF02345 // ENSGT00760000118896_8_Domain_25 (1719, 1773)

GCYHNGVYYEPEQTVLIDSCRQ
QCVCHAGKGLVCQNYSCEAGHVCQSVAGILSCVK---ELCHGVTCRPQ-------E-T-C
--Q-E-K-G-G-H-G-V-C-V-PN-Y-E-A-T-C

PF00094 // ENSGT00760000118896_8_Domain_23 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GW-D-F
-D-F--Q-G-T--C-N-Y-V-L-A-T-T-S-C-P-GV-N-S-Q-G-LTPF-T-I-T-T-K
-N-E-N-R-G-N-PA-V-S--Y-V-R-L-V-T-V-T------------------------
--------------------------------A--L--N--I--N-I--S----I--H--
K----G--E--V--G--K--V---R--V--N-----------------------------
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-----------------------GVLTALPTSVAGGRLSVTQGASKAILAADFGLRVSYD
WNWRVEVTLPSSYHGAVCGLCGNMDRNPNNDQAFPNR

PF00094 // ENSGT00760000118896_8_Domain_27 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GW-D-F-D-F--Q-G-T--C-N-Y-V-L-A-T-T-S-C-P-GV-N-S-Q-G-LTPF-T-I-T-T-K-N-E-N-R-G-N-PA-V-S--Y-V-R-L-V-T-V-T--------------------------------------------------------A--L--N--I--N-I--S----I--H--K----G--E--V--G--K--V---R--V--N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVLTALPTSVAGGRLSVTQGASKAILAADFGLRVSYDWNWRVEVTLPSSYHGAVCGLCGNMDRNPNNDQAFPNR

ENSGT00760000118896_8_Linker_27_74 (5558, 5605)

TLAH-----SIPVWGGSWRVPGW
DPLCWDEC---QGSCPTCPEDQLE

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

EYRGPGFCGPLAADAKGPFAACHAHVAPESFFKGCV
LDVCLGGGAHDILCQALATYAAACQAAGIVIEDWRTQAGC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

EIS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPNNSHYELCGPPCPAS
CPSPAPPTIPAPCEGPCAEGCQCDAGFVLSVDRCVPLDGGCGCWANNTYHEAGSEFWAGT
TCSQKCHCGP----GGGSLVCKPARCGLGEVCALLPSGQYGCRPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5996)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCRAP-PAGVENFTVTVANEHRGS--QAV-SY
-----TRSVTLHIYNHNLTLSARWPRQLQV--------DGKLVALPFQLDS-RLRAHLSG
P--DVVVAAATGLSLAFDGNSDVRLRVPAA-AGALCGLCGNYNRDPTDDLTAVGG

ENSGT00760000118896_8_Linker_77_82 (5996, 6036)

DPG--
------RWQVGGAAGCG-ECVPGPCPAPCTPEQQK

PF08742 // ENSGT00760000118896_8_Domain_82 (6036, 6126)

PFSGPDA-------------CGVIL
A-PDGPLAPCHGLLPP-AQYFQACLLDACQAQGHPGGLCPAVAAYVAACQAAGAQLGDWR
RPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGDSCPVSCPSLSAPEG-CEP--ACREGCICDAGFVLSGDTCV
PVGQCGCLHEGRYYPLGEAFYPGPECERRCECGPGGQVSCQEGTACQPYEECRIKDGVQA
CHPKGCGH

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CVVSGGIHYNTLDGRVY-DLH-------GSCSYVLARVCHPQPGDEDFAIVL
EKNAAGD-PQRLVVTVAGQVVGLAHGL--QVTVDGEAVALPVA--VGHVQVTAEGRNMVL
QTAKGLRLLFDGDAYILISVPSPFHGRTCGLCGNFNGNWSDDFVLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6451)

TVAPSVDAFGAA
WRAPG-S-SQGCGEGFGPQGWPVCSAEETA

PF08742 // ENSGT00760000118896_8_Domain_88 (6451, 6527)

PYESIKACGQLRDPKGPFAACHPVLSPSEY
FRQCVFDLCAHKGNSTFLCRSLAAYTAACQAANKAVKP-WRTDSFC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------K

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTHSC----QGSCAALSGLTGCTSHCFEGCECDDRYLLSQGICVPVQH

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF02345 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHDG
RYLPVNSSLLSSDCSERCSCSSSTGLTCQAAGCPLGRVCEVEAGSRDC------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLWSWWTL----------W-------
--------------------------AGTTLLWATLPTAEPSCQGV-QCKAGEHCQGVGG
KTRCVTQSRAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCTYTMAELCGK--DETLPAFSVEAKNE
RRSSRLVSYVGLVTVRAYSHSVTLARGEVGFARIDNQRSRLPASLSKGRLRVYQRGTQAV
VELT----FGLVVTYNWDCQLTVSLPKSFQDQVCGLCGNYNGDPADDFLMP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DLEQ-----
--------AASPDEFASSWRLDDGDYLCSHGCQSSCPACTKGQAQHYEGSRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLPK
GPFAACHESLNPRPFLEDCVYDLCVTRGERLSLCRGLTAYAQACVELGISVEDWRSPAK

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYELCAPPCPATCNSEAVPSNCSDHPCVEGCVCQSGFVASGGACVPASSCGC
VHEGRPLAPGQELWGDDLCRQRCTCDGAT-QKVTCRNTQGCPQGERCRVENGLLGCYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYISFDGRRFDFMGTCTYLLVGSCGQD--AELPTFRVLVENEHRGVQTVS
YTRAVRVEARGVKLALRREYPGKVLVDGILHYLPFQAADGQVQVFRQGNEGFVRTDFGLT
VTYNWNALVTAKVPGSYAKALCGLCGNFNGDPADDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

GGGQAA-------NALDFGNS
WQEEATP-GCGATDTGDCPK-------LDSLVAEQLESKE

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGIIADPNGPFRDCHATLD
PQGVVRNCVYDRCLLPGLSGPLCDSLATYTAACLAAGATVHPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-PS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSYGCPITCGDLPVSGGCD-SECREGCECDDGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGSYYPPGQSFY--PGPGCDSLCHCEEGGLVSCQPSSCGPHEACRPSNG
ILG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVPVGATT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGQRFDFMGTC-VYVLAQTCGT-RPGLPQFTVLQENA
PWGN-GRYSATRVVTVIVGNYTLRLEQNKRK-VMVNGVDKKLPVELAGGQV---RVF-QH
GSDA-VIKTD-FDLH-VTYDLMYYVRVTVPGNYYKQMCGLCGDYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------LAANPNEFGNSWEEPVPNSPCVPKPD--CNPDEEDCKQ--KCS
AELEEKYQQEQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGFLTS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------PTGPLAACHELIN
PQGSLKD---------------CVFDLCLGGGNISILC-------------------DNI
HAYVSICQEAGGR--------------------VEPWRTESF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
LPNSHYDLCADV------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLSCSALSAPL--QCPD---
---------GCAEGCECDPGFLYNGQ------ACVLI----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGAYYEPEEMVL
ID----------------------NCQQKCVCHVSKG----------------------M
VCQDHRCNPEEVCELSGGI------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDPCHGVTCRPQETCK-----------EQN
GQGVCVPNYDVT

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------EFDFQG-TCDYVLAAV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPGVSAEGLTPFTVTTKNKNRGNPSVSYVNRV
TVSALGTNISIHKDEVGKVRV-NGMLTALPVSVAHGQILVTHGPGKAVLVADFGLQVSYD
WDWRVEVTLPSSYHSAVCGLCGNMDLNPGNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TLAP-----SVPLWGGSWRVPSW
DPFCWDEC---QGSCPTCPEDQQQEYEGPSFCGPLVPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

PGGPFATCHAHVPPESFFKGCV
LDVCLGGGAQDLLCQALAAYAAACQAAGIVIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPRCPAS
CPSPSAPTTPAVCDGPCIEGCQCDEGFVLSAELCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

NGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYYEAGSEFLADG
TCSQLCRCGP----QGGSLVCTPASCGLGEECALLPSGQYGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYITLDGRQFDFQGTCEYLLSAPCDTP-PKGTENFTVTVTNEHRGS--QAV-SY
-----TRTVTLYVYNHVLTLSALWPQRLKV--------DGELVALPFNLGS-NLRAYLSV
S--DVVVTTDFGLSLSFDGNSFVKLHVPAAYAGALCGLCGNYNKDPSDDLTAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GNPS--
------GWQVGGALDCK-ECVPGPCPDPCTPEEQESFAGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-PDGPLAPCHTLVSP-EHYFKGCLLDACQAQGHLGGLCPAVAAYVAACQAAGAQLDEWR
RLDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFL

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPVNSHYELCGNSCPVSCPSLSEPEG-CEP--TCREGCVCNSGLVLSGGTCV
PVDQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYLLGAAFYPGPECERRCECGPGGQVTCQEGAACGPHEECRTEDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYITLDGRVY-DLH-------GSCSYVLAKVCHPKPGEEDFSIVL
EKNKDGE-PQRVLVTVVDQVVSLAGGP--KVTVDGEDVTLPVA--VGRVQVTAEGRNIVL
QTTKGLRLLFDGDTHVLISIPSPFQGRICGLCGNFNGNWSDDFTLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GDVAPSVEAFGTA
WHAPDS--SQGCIEGCGPQGCPVCLAEETAVYESNQA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLQDPKGPFSTCHNVLKPSEY
FRQCVYDQCAAKGDKAFLCRSLAAYTAACQAAGGSVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------E

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTHSC----QDSCVALSGFTGCTTRCFEGCECDDRFLLSEGVCVPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHNG
RYLPVNSTQLSADCSECCSCSSSIGLTCQAASCPEGQVCDLQEGSWV

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CRAASG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6819)

CSLSV
GANLTTFDGAHHAVGSA---GTYEFSSRCPGVQE-NIPWYRVVADVQPCQNNVKAVSTVH
IFFQDGIVTVTANKGM-WVN-GLRV----GLPAEVLTSVSVKRGSDGSILVHQKEGVQVR
LGSDGHLDVMVGDDHAGMLCGACGNFDGDRTNDLDDSQGETVMEKWKAPDFSPCHN----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLWSWWAL----------W-------
--------------------------AGATLLWARLSTAETSCQGM-RCTSGQRCQMVSG
KASCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CRAQGDPHYTTFDGRRYDMMGTCSYTIAELTGE--DMSLPAFSVEAKNE
HRGSLLVSYVGLVTVYAYSHSVSLVRGETGFARIDNQRSRLPASLSDGQLRVYQSGTQGV
IELD----FGLVVTYNWDSQLTVSLPTRFQNQVWGLCGNYNGDPADDFLTPD

ENSGT00760000118896_8_Linker_4_8 (653, 713)

GVQ-----
--------APDALEFANSWKLDDGDYLCDDGCHGNCPSCTAGQTQHYEGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGLLTLAT
GPFSACHEFLDPKPFLEDCVFDLCVTGGERLSLCRSLAAYAQACAELGVPDGNWRSHAG

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYDTCSPACPASCNSEAVPTNCSGRPCVEGCVCLPGFVASGGECVPESSCGC
IYQGRPLAPGQEVFADDLCRQRCTCDAST-QKVICKDTSGCPSGERCRVLNGLQGCYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1061)

CEASGDPHYVSFDGKRFDFMGTCAYLLVGSCGQD--AALPEFKVLVENEHRGSQTVS
YTRAVRVVAHGVEVAVRREYPARAMVDGILQYLPFQAADGKIEVFRQGNDAVIRTDFGLT
VTFNWDARVTAKVPSSYAKAVCGLCGNFNGDPDDDLALKD

ENSGT00760000118896_8_Linker_11_13 (1061, 1121)

GGQAN-------STLDFGNS
WQEEIIP-GCGATNPGDCSQ-------LDSLVAEQQQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILTDSSGPFRECHKLLN
PQGALRDCVYDLCLLPGQSKPLCDALAAYAAACQAAGGTVHPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-PT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPNS---------HYEQCSYGCPISCGDLKVSQGCG-SECQESCVCDDGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGNYYPSGETFY--PGPGCDSLCHCHEGGVVSCKPSSCGSHETCQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVPAGTTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYVTYDGQRFDFMGTC-VYVLTQTCGT-LPGLDQFTVLQENE
PWGN-GYASATKAITVLVANHTLRLEQSRWK-VQVDGVDMKLPVDLDGGKI---RVS-QH
GSDV-VIETD-FGLR-VLYDLMYYVQVTIPSNYYQQMCGLCGDYNGDPKDDFQKPN

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------LASDPTDFGNSWEEVVPDSPCAPVTP--PCT-GDSCGT--GCS
PELEDKYYGVEF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------TSGPLAACHKLID
PKGLLED---------------CVFDLCQSEGNLSILC-------------------NNI
HAYVSACQAAGGQ--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPLE-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCWALSAPP--KCPE---
---------VCAEGCECDSGFLYNGK------ACVPV----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEESVL
IE----------------------SCQQQCVCHSGEG----------------------M
VCKNHSCNPGQVCEPSGGI------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCHNVTCRPQETCK-----------DQG
GQAVCVPNYNST

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------NFDFMG-TCSYLLAGT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ACPGVSAEGLTPFTVTTKNENRGNPAVSYVRLV
TVTTYNTNITIHKNEIGKVRV-NGVLMVLPVYLAGGRVSVVHGGFKAILVTDFGLQVTYD
WNMRVEVTLPSSYHDAVCGLCGNMDKNPQNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5620)

TMAP-----SIPTWGGSWQIPGW
DPLCWNEC---QGSCPVCPENKLEEYESPGYCGPLAPGA

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

GGPFANCHAHVPPENFFKGCV
LDVCMGGQVKDILCQSLAAYAAACQAAGIQIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEMS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPSPARHTTPAACGGPCVEGCQCDQGFVLSAGQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DSGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYHEAGTEFWTDA
SCSERCRCEP----GSESLNCTSASCGLGEECALLPSGQLGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPASI----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCQTP-PAGTEYFNVTVVNEHRGS--QAV-SY
-----TRSVTLNIYGLSLTLSASWPRQLQV--------NGEFVALPFYLDE-RLSIYLSG
A--DVVVKTAAGLSLTFDGNSFVRLHVPAAYAGALCGLCGNYNKNPNDDLTAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPE--
------GWKVGGAPGCDDQCESEPCPETCTPKEQESFSGPNA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIS
D-PAGPLAPCHSLLPP-TQYFEACLLDACQAEGHPGGLCPAVATYVAACQAAGAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPDNSHYQLCGDSCPVSCPSLLAPEG-CET--TCREGCACDSGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6241)

GCLYNGRYYQLGATFYPGPECERLCECGADGQVTCKEGSDCKPYEECRIENGVQA

ENSGT00760000118896_8_Linker_84_85 (6241, 6249)

CYPSGCGQ

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYVTLDGRVY-DLH-------GSCSYVLASVCDPKPGDEEFSIVL
EKNLAGE-PQRVVVTVAGHVVALAHGP--QVTVDDEAVVLPVT--VDRVTVTAEGRNMIL
QTKNGLKVLFDGDAHVLMSIPSSFRGQICGLCGNFNGNWSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GDLAPSTEAFAEA
WRAPGS--SPDCGEGCGDQGCPVCLAEETKEYEKNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKMQDAKGPFAACHQVLSPLEY
FRQCVYDMCANKGNKTYLCQSLAAYTAACQAAGATVQP-WRTEDF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTSSC----KGSCAALAGLTQCSTRCFEGCECDDHFLLSQGVCVPAQQ

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTYNG
HYMPVNSSLLTSDCSQLCCCSGSTGLSCHPTSCPSGQVCKLQDGVRSC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QPAQG-V

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6814)

CSITV
GANLTTFDGAYNAISSP---GVYEVSSLCPGIQK-PVPWYRVVADVQSCDGNDKIVDKVH
IFFQDGLVTVTQNNGV-WVN-GLRV----DLPASVLTSVSVKRLPDGSMLVHQEGGVQVR
LGIDGHLDVMVGDDHAGILCGACGNFDGDQTNDKFGSQENTSMEKWEAQDFSPCSS----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MASLWSWRTL----------W-------
--------------------------TGAALLWALISLGEPSCQGV-QCAAGQRCQVANG
KTRCMTESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGT--DETLPAFSVEAKNE
HRGSRQVSYVGLVTVHAYSYRVSLVRGEIGFARINNQRSRLPASLSGGRLRVYQSGTRGV
VELD----FGLVVTYNWDCQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DWEQ-----
--------ATDAVEFANSWKLDDGDFLCDDGCHGNCPSCTAGQIQHYKGDRV

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLPS
GPFSACHESLDPKSFLEDCVYDLCVTGGERLSLCRSLSAYAQACMELGFSLGDWRSPSN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSFYDSCSPACPASCNSEAAPANCSGRPCVEGCVCLPGFVASGGACVPASS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TFEGRPLAPGQEVLADDLCRRRCTCDGAT-QQVTCRDTAGCPAGERCRVQDGLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDI
FGH

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1061)

CQATGDPHYVSFDGRRFDFMGTCTYLLVGSCGQA--QALPDFRVLVENEHRGSQSVS
YTRAVRLEARGVQVEVRREHPGRVLVDGILQYLPFQAADGQVVAFREGNDAVVRTDFGLT
VTYNWDAHVTVKVPGSYANALCGLCGNFNGDPSDDLTLQG

ENSGT00760000118896_8_Linker_11_13 (1061, 1121)

GGQTD-------SALDFGNS
WQEGTSP-GCGAVDPGDCPQ-------LDSLVAQQLQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGVLADPEGPFRECHMLLD
PQGAVRDCVYDRCLLPGQSGPLCDALASYAAVCQAFGATVHPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-MT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HFEVCHRGCPLSCGDLPVPGGCG-TECQESCVCDEGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHEGVYHPPGQTFY--PGPGCDSLCHCQEGGLVSCEPSTCGPHEACQPSNG
ILG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVPVSTTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGHRFDFMGTC-VYVLAQTCGT-RPGLHQFTVLQENE
AWGN-GKVSVTKAITVQVSNYTLRLEQKKWK-VTVNGVDMKFPVVLDEGRI---RVS-QH
GSDV-VIETD-FGLR-VTYDLMYYVRVTIPGNYYQQMCGLCGDYDGDPKDDLQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAANPNEFGNSWEEMVPGSPCAPVPD--DCTPGEDCGD--KCS
PELQDKYQSQQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------PEGPLAACHKLLD
PQGPLQD---------------CVFDLCLGGGNLSILC-------------------SNI
HSYVSACQAAGGQ--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYELCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCAALSAPP--LCPD---
---------GCAEGCECDSGFLYNGK------DCVPI----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEQTVL
IE----------------------NCQQQCVCHAGQG----------------------M
VCQDHSCKPGQVCQPSEGV------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDPCHGVTCRPQETCK-----------EQD
GQGVCVPNYNST

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------NFDFQG-TCSYLLAGT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPGVSVQGLTPFSVTTKNENRGSPAVSYVKLV
TVNALNTNISIHKNEIGKVRV-NGVLTALPVSVAGRRISVTHGASKAVLVTDFGLQVTYD
WNWRVEVTLPSSYHGAVCGLCGNMDQNPNNDKVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5620)

TQAP-----SIPTWGGSWQVPGW
DPLCWNEC---QGSCPTCPEDRLEEYEGPGFCGPLAPGT

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

GGPFASCHAHVPPESFFKGCV
LDVCLGGGAQDLLCQALAAYATACQAAGIVIKDWRTETG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CELP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPGPSTRPAACDGPCTEGCQCDQGFVLSADRCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEPGSEFWTDA
TCSRLCYCGP----GGGSLVCSSASCGQGEECALLPSGQIGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPAST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5992)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCHAP-PKGAENFTVTVANEHRGS--QAV-SY
-----TRSVTLNIYGHSLTLSARWPRKLQV--------DGEFVALPFRLAP-RLHAYVSG
A--DVVVTTASGLSLAFDGNSFVRLRVPAAYAGALCGLCGNYNQDPGDDLT

ENSGT00760000118896_8_Linker_77_82 (5992, 6056)

AVKGDPA--
------GWQVGGAPGCG-ECTPGPCPQPCTPEQQEPFRGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-PDGPLAPCHSLVPP-EKYFEACLVDACQVQGHPGGLCPAVATYVAACQAAGAQLEEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CSANSHYQLCGDSCPVSCPSLSAPEG-CET--TCREGCVCDSGFVLSGDACV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHGGRYYPLGAAFYPGPECERRCECGPGGQVSCQEGAACGPYEECRIDNGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYVTLDGRVY-DLH-------GSCSYVLAQVCHPKPGDEDFSIVL
EKSSTGD-PQQVVVTVAGQVVVLAQGP--QVIVDGEAVALPVA--VGHVRVTAEGRNMIL
QTTKGLRLLFDGDTHVLISIPSPFHGRVCGLCGNFNGNWSDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GAVAHSVEAFGAA
WRVPSS--SPGCGEGCGPKGCPVCLAEETATYENNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGRIRDPHGPFATCHQVLSPSEY
FRQCVYDLCAHKGDRAYLCRGLAAYTAACQAAGAAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTLSC----QDSCAALSGLTGCTSRCFEGCECDERFLLSQGACVPAQE

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHGG
RYLPVNSSLLSSDCSERCCCSLKTGLTCHAASCPLGHVCAIQAEARV

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWAARG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6817)

CSLSV
GANLTTFDGAYSAVSSP---GIYELSSHCPGLQS-TVPWYRVVADVQHCDGRVEAVGEVH
VFFQDGMVTVTPSKGV-WVN-GLRV----DLPADVLTSVSVRRAPDGAMLVRQKAGIQVW
LGTDGHLAVMVSDDHAGRLCGACGNFDGDQSNDVHDSPGKTAMEKWRAQDFSPCYN----
-

MGSLRSWWSLWAGAALLWGWTQEAAGDPVDPGSEGFLMTFLQNYQPGDSAASLHLLISSL
LES-------PAAVSVVSQVDKTLQKVIARLGQSAVVNSNATAEMIGSTAFQHAMVVHSD
REVLLL------------ALLPVNTLGKKHFVLALLGSS----TKFAAVAGSAGASVTIN
LEGAVMFQHKIHPASGVPSMTLQPCEVAQVQSPVDLSGSKVMASSLVAVLSGHS------
---------LPTSAWSMQYVVPL--VS----QSCLDLAYVVVVSQATKLTYNHGSTTGSW
GLQMGDMVQFEVWPSRHRYLPADVGIQVLLFGTMVIKNDMTYGPYLALVPDVVTYCHTHM
VQSVPGTWGVAAVMA-TKLVSGLTV--DG-DTPKARLDLVAVPGSEFSYAEVDLGIANRI
NT---VSANASIELLAFRLGQTVGFGTAAACSHIAAV-----------------------
-ALGEAESKAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRHYNMMGTCTYSMVELCGM--DLTLPAFAVEAKNE
HRTSRLVSYVGLVTVRAYSQVVMLARGETGFARINNQHSLLPVSLNENRLRVYQSGTRAV
VELD----FGLVVTYDWDSVMTVTLPDKFKDQVCGLCGNYNGNPDDDFLTFDGVE-----
--------AANAVELANSWKLDDGDYLCDDGCLNNCPSCSKDETDFYEGEFMCGLXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPENSKYNSCGPACPETCNPDFTPSNCSERPCVESCECLPGFVASGGACIPQSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF02345 // ENSGT00760000118896_8_Domain_10 (839, 897)

GC
SFEGHLLAPGQEMWTDDRCRQRCTCNSTT-QEVSCINTQGCPPGESCRVENELLGC

ENSGT00760000118896_8_Linker_10_11 (897, 904)

YPGS
FAT

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 985)

CQASGDPHYVTFDGRRYDFMGACVYLLAGSCNQN--SALPEFRVLVENEHRGSQAVS
YTRAVRVEVYGVELVISKDYPGQVMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXS
WEEET--PGCEATDP-ECPQMR------------

PF08742 // ENSGT00760000118896_8_Domain_13 (1115, 1190)

QVEKKEKCGILDP--TVLEKCHKKLD
PQAVVRDCVYDLCLVPDQPDLLCDALAAYAAMCQTAGVTLDPWRSDTLC

ENSGT00760000118896_8_Linker_13_14 (1190, 1204)

P----------
-FN

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CTEHS---------HYEACAQGCPLTCGEVLRSGGCG-SECYESCVCDDGYLLSGNT
CVPIAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1269)

CG

PF00093 // ENSGT00760000118896_8_Domain_18 (1269, 1309)

CVQNGAYYPPGQTFY--PGPKCDSLCTCQAGGQLSCEPSS

ENSGT00760000118896_8_Linker_18_20 (1309, 1332)

CGPQEICQVSDG
VLGCVPVSSAT

PF00094 // ENSGT00760000118896_8_Domain_20 (1332, 1380)

CQASGDPHYVTFDGRRYDFMGAC-VYLLAGTCGK--HDLPEFRVLVENE
HRGX-XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
-----------------XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX--X-------------------XXXXXXXXXXXXXXXXX-
-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP

PF02345 // ENSGT00760000118896_8_Domain_25 (1730, 1773)

EQTVLIDNCQQ
ECVCHEGV-LTCQAHSCEPGQLCQPSGGVLSCVTK--DPCEDVTCPPQSTCKEQNGQGVC
VSN--------------------------SGTTC---

PF00094 // ENSGT00760000118896_8_Domain_29 (1838, 1957)

-WLWGDPHYHSFDGYN----FDF
----------QGTCSYVLA--------EVGDCPG-------VDAGNLTHFAVTT-----K
NE-----NRGNPSVSFVKLV---TVTVLDMNISIHKGEIGKIRXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00094 // ENSGT00760000118896_8_Domain_54 (3952, 4033)

VNGVALTPP
VELEEGQIRIYQHGSDIVVET-----DFGLRVAYDLMYYVRVTVPGSYQQHLCGLCGDYN
GNPTDDFQKPDG

ENSGT00760000118896_8_Linker_54_55 (4033, 4100)

SQATNPN------DFGNSWEEDVPGSSCQPPPDCTPGGDIC-------
--------EDNQCSEELET

PF08742 // ENSGT00760000118896_8_Domain_55 (4100, 4244)

QYKGEEYCGF---------------LTSATGPLASCHALLD
PTGFLKD---------------CVFDLCQSEGSLDILC-------------------SNL
HAYVSACQAAGGQ--------------------VDSWRNDTFCPLK-------------C
PPNSHYELCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSQSCSARNASHCDGCAEGCX
XXXXXXXXXXX-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------XX---------------
----------XX---------------------------------X--------------
------------------------------------------------------------
-----------------------------------------------------X-X-X-X
XXXXXXXXXX-X-X-X-X-X-X-X-X-X------------X-X-----------------
------------------X-X-X-X-X-X----------X-X-X-X------X-X--X--
--X-X---------------------------------------------------X-X-
X-X---------------------------------------------------------
-----------XXXXXXXXXXXXXXXXPCEDVTCPPQSTCKEQNGQGVCVSNSGTT

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYHSFDGYNFDFQGTCSYVLAEVGDCPGVDAGNLTHFAVTTKNENRGNPSVSFVKLV
TVTVLDMNISIHKGEIGKIRV-NGVLTTLPASLADGQISVTQGVSKAVLVTDFGLQVTYD
WDWRVEVTLPNSYLGAVCGLCGNMDGDPSNDQVFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5605)

TAAP-----SIPDWGGSWQTPDW
DSQCWDEC---QGSCPTCSEDQKK

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

KYQGSDFCGPLAPGIEGLFSKCHSYVPPDIYFEGCV
LDVCLGGGDRDILCKALAAYAALCQAAGAELQDWRKQLKC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

EIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPDHSHYELCGSPCPAT
CSSPENTTTSALCQGPCVEGCQCDAGFVLSGDRCVSLEDGCGCWENGIYYERGSEFWTDA
TCSERCRCEP----ACGSLICMSSRCGKGEECALQSSGEYSCQPESI----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5998)

C
QAWGDPHYVTLDGHQFDFQGACEYLLSAPCSKL-PEGTEKFNVTVANQQLGS--QAV-SY
-----THSVTLYIYGHSLTLSASWPQQLQV--------DGRLVTLPYQLDS-RLNAYLSG
I--DVVVTTAAGISLSY-GDSFVRLHVPSVYAHALCGLCGNYNQDPSDDLTDK--GP

ENSGT00760000118896_8_Linker_77_82 (5998, 6034)

E--
------DWQVGGEPGCG-VCESGSCPEPCTPEE

PF08742 // ENSGT00760000118896_8_Domain_82 (6034, 6126)

QEAFR--DA-------------CSVIS
D-PKGPLAPCHSFLPP-EQYFQGCLLDACQTQGHESGLCTAVASYVTACQAAGAQLEEWR
QPGFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

APQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGDSCSVSCPTLSAPEG-CKS--TCREGCFCDAGYVLSGDTCV
PLGQCGCLHEGQYYPLGATFYPGPECERYCECGPDGLVSCQEGVACGPYEECKVQNGIQA
CYPNGSGH

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CLADGGIHYVSLDGHAY-DLH-------GSCSYILAQVCQPEPGDEDFTIIL
EKDAAGE-PTGLLVTVADQVVSLDLEL--QVTIDGEEMALPAA--VGHVRVTAEGHNLIL
QTTGGLRLLLNSNAHVLISIPSTFHGRVCGLCGNFNGNWTDDFVLPGG

ENSGT00760000118896_8_Linker_85_88 (6409, 6451)

TVAPDADAFGAE
WRAPG-S-SQDCSEGCGTQDCPTCSANETA

PF08742 // ENSGT00760000118896_8_Domain_88 (6451, 6527)

AYESSEICGKLLDANGTFASCHEVLSPSEY
FRQCVYGLCSSKGDMTFLCHSLAAYVADCQAAGVTLKP-WRTDSFCPA-------EC--A
RHYSLCTNTC----QGSCSALSGLTGCN-SCFEGCECDDRYLLSDGVCIPIQDC

PF02345 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTYEG
RYMPVNTSLLSSDCSESCYCS-DNGLTCSANECQVGFVCDIHEGTRVC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QVSQG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6820)

CSLTA
GSNLTTFDGALGAFSSP---GVYDLSSRCPGLAS-HIPWYRVVAAVQSCEDKAKTVVQIH
VFFEDGIVTVIPGKGV-WVN-GLPV----ALPVDVLTSVSVSQTSDGSILVQQKAGVSVW
LGTDGQLTVAVSDDHAGALCGACGNFDRNPANDLGDSQEDTDMDKWRAPDFSPCEP----
-

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--GA

PF08742 // ENSGT00760000118896_8_Domain_13 (1145, 1189)

VRDCVYDRCLLPGQSQPLCDALATYAAACQAAGAIVHPWRSETLCQ----------
-WQLGGARPYEFLISMAPLPPSMHGCPLSCGDLPVSGGCG-SKDYEDCVCDEGFALSGES
CVPLASC

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCAYQGTYYPPGETFY--PGPGCDSLCHCQEGGLVSCEPSTCGPHEACQPSGG
ILG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSVI

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CEASGDPHYTTFDGLHFDFMGTC-VYTLAQTCGN-RSGLHQFAILQENE
AWGN-GKVSVTKAITVQVANFTLRLEQGQQK-VTVNGVDMKLPVELAEGQI---RAY-QH
GSDV-VIETH-FGLR-VAYDLEYYVRVTIPGNYYQQMCGLCGDYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAENPTEFGNSWEEAVPGSPCLPPPT--CEPGSEDCDSDLTCP
PELEDKYQKEQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLL--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------TSTTGPLASCHKLVS
PNRPFQD---------------CVFDLCVGGGNLSILC-------------------NNI
HAYVSACQAAGIQ--------------------VEPWRTESF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPMQ-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPNSHYELCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSALSAPP--KCPE---
---------DCAEGCQCDSGFLYDGK------ACVPI----QS

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPDQTLL
T----------------------DNCQQQCTCHAGQG----------------------V
VCQEHSCKPGQVCEPSGGV------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCDGVTCRPQETCK-----------DQG
GQGVCVPNYDVM

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYQSFDGQ----------------TFDFQG-TCDYVLATT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ACLGVSAQGLTPFTITTKNENRGNPAVSYVRLV
TVSTLDTNISIHKDEIGKVRV-NGVLTALPVSAAGGRLSVTHGASKAVLATDFGLQVTYD
WDWRVEVILPSSYHSAVCGLCGNMDGDPNNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5620)

TLAP-----SIPIWGGSWRVPGW
DPLCWDEC---QGSCPTCPEDQQEELKGPGFCGPLAPGT

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

GGPFAACHAQVPPDSFFEGCV
LDVCLGGGAHNLLCQALASYAAACQAAGIVIEDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEMS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5739)

CPENSHYELCGSPCPAS
CPSPAPPATSAPCEGPCAEGCQCDPGFVLSADRCVSLQ

ENSGT00760000118896_8_Linker_75_76 (5739, 5742)

DGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYYEANSEFWADD
TCSQWCHCGP----GGGSLLCKPSSCGQGEECALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

HPIST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5991)

C
EAWGDPHYITLDGHQFDFQGTCEYLLSAPCNGS-STKAENFSVTVVNEHRGS--QAV-SY
-----TRSVTLHIYGHSLTLSALWPGQLQV--------DGELVALPFQLDS-GLHAYISG
A--DVVVTTTFGLSLAFDGSSSVRLRVPAAYAGALCGLCGNYNKDPADDL

ENSGT00760000118896_8_Linker_77_82 (5991, 6056)

EAV----A--
------GWQVGGDPGCG-ECVPGPCPEPCTPEQQEPFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-LDGPLAPCHCFVLP-EKYFEACLLDTCQAQGHPGGLCPAVAAYVAACQAAGVQLDEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFE

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGNSCPVSCPSLSAPEG-CEP--ACREGCVCDAGYVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYQLGEAFYPGPECEQRCECEPGGQVSCQEGEACGPYEECRLENGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CLASGGIHYITLDGRVY-DLH-------GSCSYVLAKVCHPEPGDEDFTIVL
EKNAAGD--QRLVVTVADQVVTLARGP--QVTVDGETVALPVA--VGSVRVTAEGRNVVL
QTAKDLRLLFDGDAHVLISIPTPFHGRLCGLCGNFNGNWSDDFVLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6458)

TQAPSVEAFGAA
WRAPGS--SEDCGEGCGPEGCPVCLAEETAPYEGKES

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLRDSQGPFATCHALLSPSEY
FRQCVYDLCAQKGDEAFLCRSLAAYTAACQAAGAAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTHTC----QGSCAALSGLTGCTTRCFEGCECDDRFLFSQGACIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHGG
RYLPANSSLLTSDCSERCSCSSSSTLTCQAAGCPEGRVCEIQAGARD

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWAPHG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6814)

CSLSV
GANLTTFDGAHSGTYPP---GIYELSSYCPGLQK-TIPWYRVVADVQSCHGKVKGVGQVH
IFFKDGIVTVSPDKGV-WVN-GLQV----DVPAEVFTSVSVSQTRDGSMLVQQKKGVQVW
LRTSGKLDVMVSDDHAGMLCGACGNFDGDQTNDGDDSQGKTGLDRWRARDFSPW------
-

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-----------------LEGPNRL--------------------------EAR---PG

PF01826 // ENSGT00760000118896_8_Domain_33 (2579, 2639)

AP
P-CCSDSPA---P----SGCES-ACRE----GCVCDAGFVLSGD---TCV---PVG-Q

ENSGT00760000118896_8_Linker_33_34 (2639, 2640)

C

PF12714 // ENSGT00760000118896_8_Domain_34 (2640, 2792)

G
C-LHDDRYYPLG-----QTFYPG--PGCDS-----------LCH-C-RE--G--GLVSCQ
PSSCGPHETC--RPSGG-------------------------------------------
----------------------------SLG

ENSGT00760000118896_8_Linker_34_23 (2792, 2804)

CVA----VGSAT

PF00094 // ENSGT00760000118896_8_Domain_23 (2804, 3742)

CQA-SGD--PHYT---T
FDGRRF--------------------------DFMG--TC-VYVL----AQTCGTRP-GL
H-----------------QFAV----LQENV-AW-GNGRVS-------------------
-------------------V----T---------R---V---I------T--V-------
Q---V---G---N---F--T------L------R-------L------E--Q------R-
------------------------------------------------------------
-----------------------------------------------------------Q
---W---K--V-------------------T-------------------------V---
N--G---V---D--M----------K---L---P-----V---V---L--A---N--G--
-Q---I-------------R--A---S---Q--H---G---S---D--V-----------
-----V-----I--E---T---D---F--G---L------R---V---------------
-----A---Y---D---L--V---Y---Y---V---R----------------V----T-
---------I---P--G---N---Y-----Y--Q---Q---M--C---G-----------
-------L---C--G-------------N---Y---N---G----------D--------
-----------------------------------P---K---D---D------------
-----------------F--------------Q---K---P-------------------
----------------N----G---S---Q----------------------------------------------------------------------------A---G-----N---A----N---D-------F---G----N----S----W------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEAVPGSPCLPPPTCPPGSE------------G---CDTSKCPPEQEKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCHKLVDPQGPLQD---------------CVFDLCLGGGNLSILC-------------------SNIHAYVSACQAAGGH--------------------VKPWRTETFCPMK-------------CPANSHYELCADT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSLGCAALSAPL--QCPD------------GCAEGCQCDAGFLYNGE------ACVPI----QQCGCYHNGVYYEPEQTVLID----------------------DCRQQCTCHVRKG----------------------VVCQEHSCPPGQVCQPSGGV------LSCITKDPCDGVTCRPQETCK-----------EQGGQGVCVPNYEATCWLWGDPHYHSFDGR----------------AFDFQG-TCNYVLATT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GCPGVNTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKGEIGKVRV-NGVLTALPVSEANGRISVTHGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQAFPNGTLAP-----SIPIWGGSWRVPGWDPLCWDVC---PGSCPTCPEDKLEQYEGPGFCGPLVPGAGGPFATCHAHVPPESFFKGCVLDVCMGGGAHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPPATPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSHRCRCGP----GGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST----------AECQAWGDPHYVTLDGHRFDFQGNCEYLLSAPCHGL-PSGAANFTVTVANEHRGS--QAV-SY-----TRSVTLQIYNHSLTLSAR

PF00094 // ENSGT00760000118896_8_Domain_37 (2804, 3742)

CQA-SGD--PHYT---TFDGRRF--------------------------DFMG--TC-VYVL----AQTCGTRP-GLH-----------------QFAV----LQENV-AW-GNGRVS--------------------------------------V----T---------R---V---I------T--V-------Q---V---G---N---F--T------L------R-------L------E--Q------R------------------------------------------------------------------------------------------------------------------------Q---W---K--V-------------------T-------------------------V---N--G---V---D--M----------K---L---P-----V---V---L--A---N--G---Q---I-------------R--A---S---Q--H---G---S---D--V----------------V-----I--E---T---D---F--G---L------R---V--------------------A---Y---D---L--V---Y---Y---V---R----------------V----T----------I---P--G---N---Y-----Y--Q---Q---M--C---G------------------L---C--G-------------N---Y---N---G----------D-------------------------------------------P---K---D---D-----------------------------F--------------Q---K---P-----------------------------------N----G---S---Q------------------------------
----------------------------------------------A---G-----N---
A----N---D-------F---G----N----S----W-----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------EEAVPGSPCLPPPTCPPGSE---------
---G---CDTSKCPPEQEKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF08742 // ENSGT00760000118896_8_Domain_55 (4134, 4243)

XCHKLVD
PQGPLQD---------------CVFDLCLGGGNLSILC-------------------SNI
HAYVSACQAAGGH--------------------VKPWRTETF

ENSGT00760000118896_8_Linker_55_56 (4243, 4260)

CPMK-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PANSHYELCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCAALSAPL--QCPD---
---------GCAEGCQCDAGFLYNGE------ACVPI----QQ

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEQTVL
ID----------------------DCRQQCTCHVRKG----------------------V
VCQEHSCPPGQVCQPSGGV------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDPCDGVTCRPQETCK-----------EQG
GQGVCVPNYEAT

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGR----------------AFDFQG-TCNYVLATT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPGVNTQGLTPFTVTTKNENRGNPAVSYVRVV
TVAALGTNISIHKGEIGKVRV-NGVLTALPVSEANGRISVTHGASKALLVADFGLQVSYD
WNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQAFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TLAP-----SIPIWGGSWRVPGW
DPLCWDVC---PGSCPTCPEDKLEQYEGPGFCGPLVPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

AGGPFATCHAHVPPESFFKGCV
LDVCMGGGAHDILCKALASYVAACQAAGVVIEDWRAQVG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYEVCGPPCPAS
CPSPAPPATPAVCEGPCVEGCQCDAGFVLSADRCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

NNGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADG
TCSHRCRCGP----GGGSLVCTPASCGLGEVCGLLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYVTLDGHRFDFQGNCEYLLSAPCHGL-PSGAANFTVTVANEHRGS--QAV-SY
-----TRSVTLQIYNHSLTLSARWPRQLQV--------DGVFVALPFHLDS-LLHAHLSG
A--DVVVTTTSGLSLTFDGDSFVRLRVPAAYAGALCGLCGNYNQDPADDLKAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPA--
------GWQVGGATGCG-ECVSGPCPSQCTPEQQESFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-TNGSLAPCHGLVPP-AQYFQGCLLDACQVQGHPGGLCPAVAAYVAACQAAGAQLGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGDSCPVSCPSLSAPEG-CES--ACREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLYDGRYYPLGEAFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVRA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HATGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYVTLDGRVF-DLH-------GSCSYVLAQVCQPKPGDEDFSIVL
EKNAAGD-PQRLVVTVSGQVVSLAQGQ--QVTVDGEAVALPVA--VGRVRVTAEGRNMVL
QTTKGLRLLFDGDAQVLMSVPSSFRGRLCGLCGNFNGNWSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GLAASSVETFGAA
WRAPGS--SKGCGEGCGPQGCPVCSAEETAPYESNKA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLRNPQGPFATCQAVLSPSEY
FRQCVYDLCAQKGDTAFLCRSLAAYTAACQAAGVAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------P

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTHTC----QGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG
RYLPVSRGWGGQRG----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--TQTQESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCSE--DDTLPAFSVEAKNE
HRGSRRVSYVGLVTVHAYSHSVSLIRGEVGFVLVDKQRSRLPVSLSEGRLRVYQSGLQAV
VELV----FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLAPD

ENSGT00760000118896_8_Linker_4_8 (653, 713)

GNL-----
--------APDAVEFASSWKLDDGDYLCEDGCQNNCPSCTPGQAQHYEGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTKLD
GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGNWRPPANC
RE----------------------------------------------------------
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-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLWSCWAL----------W-------
--------------------------AAASLLWARLSPAEASCQGI-QCTSGQRCQMVSG
KARCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELHST--KKSLLAFKVEAKNE
HRGTNKVSYVRFVTVRAYNHTVSLAYGEIGIAQINYQYSSLPASLSDGRLRVYQSGTQGV
VELD----FGLVVTYDWDCQLTLSLPKRFQDQVSGLCGNYNGDPADDFRMPDG

ENSGT00760000118896_8_Linker_4_8 (654, 713)

KQ-----
--------ASDVLNFTKSWKLDNGDLLCDDGCFGNCPSCTTSQTQFFKGDCL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGILTLST
GPFADCHDFLDPKPFLEECVYDMCVTRGERLTLCHGLSAYARACADLGISVREWRSRTN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
SMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSYYDLCSPACPASCNSEAAPANCSRRPCVEGCVCLPGFVSNRGLCVPVSSCGC
TFQGRLLAPGQEVFADDLCRQRCTCDAAT-QKVICRDTSGCLSGERCGIQNGFLGCYPEY
FGS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CRASGDPHYMTFDRRNYNFMGTCTYMLTTSCGQH--PSLPDFKVIMENERRGSQSVS
FVHSVQLEVYGVKLEVPRNYPGKVLLDGVIRYLPFQAAGGKIVAFRRGMYAVLRTNFGLT
LSFNWDTHVTAKVPSSYAKAVCGLCGNFNGEPRDDLGQQ

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

DKGEAL-------DPRDFGKK
WMVTEKP-GCRTDEQLRCPH-------MNSKSVV--KNKE

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

KCKILRDKEGQFRHCWKVPM
FNSALIECAYDSCRMPGQTKPLCDALATYTAICQAEGITVYPWRSEKL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-MN

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCHRGCPLTCGDLPVPGGCG-SHCQEACVCDEGFVLSGET
CVPLSS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVYQGVYHQAEEDFY--PGPECNSLCHCHKGGLVSCQPSYCSPYEVCKVSSG
VLR

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVNSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CRVSGASHYTTFDGRRFDFIGTC-VYVLVQTCWT-RPGLQQFTILQENA
VSGNNTEVSVTKMITIQVANYTLKLQQNQWK-VTVNGVNMKMPVVLDGGSV---QAL-QH
GVDV-VIKTR-FGLQ-VSYDLNNNVRVTVPRNYYNYLCGLCGDYNDDPKNDLQKSD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAVSPSELGNSWAKAVPGSFCMPQPA--CKPGQD-CQA--KCS
PAMEKKYHGVQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLSS------------------------------------------
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------------------------------------------------------------
-----------------------------------------------PTGPLAACHKLLD
PQDLFKD---------------CVFDLCLNGGNLSILC-------------------NHI
HNYVSICQAAGGH--------------------VKPWRNKTF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYAVLADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSTITTPI--QCLE---
---------TCSEGCECDSDFLQSLT------TCVPM----EK

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCHHNGVYYEPEESVL
IE----------------------NCQQQCVCHPGKG----------------------M
VCQDHSCKPGQVCEPSGGI------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCQGVTCRSQETCR-----------EKG
GKGVCVPNYNSK

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWVWGDPHYQSFDGL----------------NANFHG-TCSYLLAGS-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VCPGVSAEGLTPFTVITKHESQGNPAVSSVKKV
TVTAYNTSIAVHKKGNGRVQV-NGVLKALPVYLAGGQISVVHGGSKAVLVTDFGLQVTYD
WNWRVEVTLPSSYHGAVCGLCGNMDKNPQNDLVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5620)

TVAP-----SMPTWGGSWQIPGW
DPLCWNEC---QGSCPMCPEDRVEMYEGPGYCGPLAPGT

PF08742 // ENSGT00760000118896_8_Domain_74 (5620, 5680)

VGPFASCHAHVPPESFFKGCV
LDVCLGGGIKDILCQALAAYAAACQAAGIKIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPARHTTPAACDGPCVEGCQCDQGFVLSAKQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYYEPGTEFWTDA
TCSKRCHCGP----GGESLVCTSASCGLGEECALLPSGQLGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5991)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCHVP-PTGTEFFSVTVINEHRGS--QAV-SY
-----TRTVTLNIYGLSLTLSARWPRQLQV--------NEEMMMLPFQLDS-RLFAYLSG
I--GLVVNTTVGLSLAFDGDSFVRLRVPAAYAGALCGLCGNYNKNPKDDL

ENSGT00760000118896_8_Linker_77_82 (5991, 6056)

TAV-GKPE--
------GWKVGGTLNCD-QCVAGPCPQPCTPEQQEPFRGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIS
S-PEGPLAPCHSLVPP-TQYFEACLMDACQVQGHPGGLCPAIAAYVAACQDSRAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYQLCGDSCPVSCPSLLPPEG-CET--TCREGCVCDSGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHNGRYYLLGATFYPGPECERLCGCGPGGQVSCQI-ESCGIHEECQIVDGIHA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6254)

HPKSFKSVLVLN

PF00094 // ENSGT00760000118896_8_Domain_85 (6254, 6409)

GIHYVTLDGRVY-DLY-------GSCSYVLAQVCYPKPGLKEFSIVL
EKNLAGE-PQRVVVTVDGQDVVLAKGP--QVTVESEAVTLPVV--IGSMYVTVEGRNMFL
QTKWGLKLLFDGDAHILMVIPSPFYGRICGLCGNFNGNQSDDFVLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6458)

TLAPNVEAFGAA
WRAPGS--SLGCGEGCGPQGCPVCLAEKREAYEKNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQISNPQGPFKDCHQVLSPLEY
FRQCVFNMCAHKRKQVYLCRSLAAYTAACQAVGATVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------R

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPDH
SHYSVCMSSC----QGSCAALSGLTQCTTRCFEGCECDNHYLLSQGVCIPAHD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTYNG
QYMPVNTSRMTSDCTKRCSCSTRTGLTCRAAGCPSGHVCEIRAGVRD

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWPAKG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6818)

CSISV
EANLTTFDGARNAISSP---GVYELSSRCPGLQK-TVPWYRVVADVQPRHGNDKVIGKVH
VFFKNGMVTVTQSKGV-WVN-GLRV----DPPANVLTSVSVSKMPDGSMLIHQKAGVQVR
LGINGQLDVMVGDDHAALLCGACGNFDGDQKNDVHKYQGKTLMDKWKAQDFSSCSN----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLWSWWAL----------W-------
--------------------------AGAALLWARLSAAETSCQGM-RCTSGQCCQMVSG
KASCVTESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCTYTLAELHST--KNSLLAFKVEAKNE
HRSTSKVSYVRFVTVHAYNHTVSLSYGEIGIARIDYQYSSLPASLGEGRLRVYQSGTRGM
IELD----FGLLVTFDWDYQLTVSLPKRFQDQVWGLCGNYNGDPADDFRMPDG

ENSGT00760000118896_8_Linker_4_8 (654, 713)

KQ-----
--------ASDVLNFTKSWKLDNGDLLCDDGCYSNCPSCTTSQSELFKGDLL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLPM
GPFADCHGFLDPQPFLEECVYDMCVTGGERLTLCHGLSAYARACVDLGISVREWRSRTN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLI

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSHYELCSPACPASCNSEALPTNCSGRPCVEGCVCLPGFVVNRGHCVPVSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TYQGRLLAPGQEVFADDLCRQRCTCDAAT-LKVICRDTAGCLPGEHCGVQDGFLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPEY
FRS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYRSLDMRSYNFMGTCSYMLTTACGQH--PSLPDFKVVMENERRGSQSVS
FVHSVQLEVYGVKLEVPRDYPGKVLMDGIIHYLPFQAAGGKVVAFRKGKYAVLRTNFGLT
VSFNWDTHVTAKMPSNYAKAVCGLCGDFNGNPRDDLGLQ

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

SKGEAL-------DPRDFGKK
WLVTMKP-GCRTDEQLLCPN-------MSSEVAM--KNRK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

KCKILRDKDSQFRECWKVSA
FNSALIECIYDSCRMPGQTKPLCDTLATYTAICQAEGVTVYPWRSEKL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-MN

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCQRGCPLTCGDLPVPGGCG-TDCHEACVCDEGFVLSGET
CIPLSS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCLYQGVYHHVGEDFY--PGPECNSICHCHEGGLVSCQASYCSPQEICKVSYG
ILR

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVDSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CRVSGSIHYTTFDGRHFDFMGTS-VYVLAQTCWT-RPGLKPFTVLQENA
VRGN-EQVAVTKMITVQVDNYTLQLEQNQWK-VKVNGVTTKMPVILDEGSV---QAF-QH
GLDV-VIKTR-FGLH-VSYDLNSNVRVTIPHNYYKHMCGLCGDYNEDPKNDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAVNPSDLGNSWQKTVPGSSHRPQPA--CKPGQD-CKP--KCS
PDMEKKYHDNQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTN------------------------------------------
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-----------------------------------------------LTGPLADCHKLID
PQDPLKD---------------CVFDLCLGGGNLSILC-------------------SSI
HAYVSACQAAGGH--------------------VKPWRTKIF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PAHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSTITTPI--ECLD---
---------MCSEGCECDTDYLQSTT------GCVPM----EK

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCHHDGVYYEPEESVL
IE----------------------SCQQQCVCHSGEG----------------------M
VCKDHSCKPGQVCEPSGGI------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCQGVTCRSQETCT-----------EKS
GKGVCIPNYEAK

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CLAWGDPHYHSFDGL----------------NTNFHG-TCSYLLAGS-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VCLGVSTGGLTPFTVITKHESQGSPAVSNVKRV
TVTTYNTSITIHKKEIGRVQV-NGVLTALPVYLAGGRISVVHGGSKAILVTDFGLQVIYD
WNWRVEVVLSSSYYGAVCGLCGNMDKNPQNDQVFPNGTTAP-----SIPTWGGSWQIPGW
DPLCWNEC---QG-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------CQPTSI----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5991)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCQMP-PAGTEYFNVTVVNEHRGS--QAV-SY
-----TRSVTLNIYGLSLTLSASWPRQLQV--------DGELIMLPFQLDS-RLLVHLSG
T--GLVVNTNWGLSLAFK-DNFLRLRVPAVYAGALCGLCGNYNKNPNDDE

ENSGT00760000118896_8_Linker_77_82 (5991, 6056)

TAV-GKPE--
------SWKVGGAPGCD-QCMKEQCPKPCTPEQRKPFRGPNA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIS
D-PAGPLAPCHSLLPP-TQYFEACLLDACQVQGHPGGLCPALATYVAACQDAGAHLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPDNSHYQLCGDSCPVSCPSLLAPEG-CET--TCREGCACDSGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLYNGRYYQLGATFYPGPECEWLCVCKSDGQVICQI-ESCGIHEECRLVDGVRA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6254)

HPRNSKLMVVLN

PF00094 // ENSGT00760000118896_8_Domain_85 (6254, 6408)

GIHYATPDGLVY-DLY-------GSCSYILAQVCHPKPGDEEFSIVL
EKNLAGE-TQRVVVIVAGHVVVLAQGP--QVTVDGEAVNLPVV--VGSMFITVESRNMFF
QTKRGLKVLFDGDSHILLSIPSPFRGRICGLSGNFNGNRSDDFALPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GALASSAEAFGAA
WRAPGS--PLGCGEGCGAQGCPVCSAKEREAHEKNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKIQDAKGPFAACHQVLSPLEY
FRQCVFDLCAHKGSKTYLCQSLAAYTAACQAAGATVQP-WRTEDF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPTH
SHYSVCTRSC----QDSCAALAGLTQCTTQCFEGFECDDHFLLSQGVCIPAQH

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTFNG
HYIPMNSSLMSSDCSERCFCSPSTGLTCYPTGCSPGQVCEIRAGVRNCWPAKG-LCSLSV
KGNLITFDGVHNAISSP---GVYELSSRCPGLKK-TVPWYRVVADV---HGNDKIVNKVH
IFFQDGLVTVTRSNGV-W------------------------------------------
------------------------------------------------------------
-

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--------------------------------------------------------S

PF00094 // ENSGT00760000118896_8_Domain_70 (5458, 5552)

RTV
RVRVYGTEVAISHEHPGRILL-NGSPTHLPYLPNDLPLTVHRVGFLAELRTGFDLIVTFD
WSNQVRVSVPVAYEGALRGLCGDLDGNPGND

ENSGT00760000118896_8_Linker_70_74 (5552, 5607)

LIPRGEPRDPASKPDDPVAFAGSWREPGP
DGQTCAEPVVRPAACPNPEAAERAQR

PF08742 // ENSGT00760000118896_8_Domain_74 (5607, 5680)

QSPVACGLL-VDPKGPFRDCHAMHDPDPAFRRCT
YLSCSEPRDPDRVCQELAHYTSVCQLAGRRVDPWRSGSFCGMLCPVHSHYDVCGSGCEDT
CGSPWAP---TPCARQCLEGSTPPHPAPP-------------------------RPFSPP
S-------------VSPPDPCQGIQCEVEEVCVA-----GTCQK----------EDMAT

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
MAWGDHQFSTFDGNTYSFQGRCTYVLASLRLPEAGSGQGR-----SARRRGSGGSGE---
---RWR-------------VR--GNSGRGLSRHSNSGLDGILTKLPVSLASGAIRLSLSG
R--NIILKTNVGLSVLYRGW-ILMVRLGLRYRGRTQGLCGDFNGDSSDDVILPD

ENSGT00760000118896_8_Linker_77_82 (5995, 6041)

GRSHPG
IEAWVREWKVADDDSCSDECEP--HCSSCSPQEKQLYGSP

PF08742 // ENSGT00760000118896_8_Domain_82 (6041, 6126)

GF-------------CGILS
TGVPGPFAGCHAAVPP-AQYVENCLYYVCSNWGARQILCQALSRYAAECQRTGATLQEWR
EMAGC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PLS

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CTPGTLSTHCLRPQETLCASGIFPTG-I--PIECFEGCECPAGTLAEAGHCV
PSTACGCIHQGRYLQV--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
-

------------------------------------------------------------
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--------------------------------CQAAGATVHPWRSEELCP----------
-PS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYESCSYGCPLSCGDLPVSGGCG-SECYEGCVCDDGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYYPPGQTFY--PGPGCDSLCHCQAGGLVSCEPSSCGPHEACQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CEASGDPHYTTFDGRRFDFMGTC-VYVLAQTCGT-RPGLHNFTVLQENA
PWGN-GHVSATRVITVLVGNYTIRLEQNKWK-VTVNGVDKKLPVELDGGQI---RVF-QH
GSDV-VIETN-FGLR-VAYDLVYYVRVTVPGNYYQQMCGLCGDYNGDPKDDLQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAANPNEFGNSWEEPVPSSPCVPTPD--CTPGEEGCE---ECS
SELKEKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGFLTN------------------------------------------
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------------------------------------------------------------
-----------------------------------------------PKGPLAACHKLID
PQGPLKD---------------CVFDLCASGGNLSILC-------------------NNI
HAYVSACQAAEGQ--------------------VEPWRSETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPNSHYELCADV------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSALSTSL--QCPS---
---------GCAEGCECDSGFLYNGQ------ACVPI----QK

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYYDGAYYELEEEVL
VD----------------------NCQKQCVCHAGKG----------------------M
KCRDYSCEPGQVCEPLDGI------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDPCHGVTCRPQETCK-----------EQD
GKGVCVPNYHVT

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------EFDFQG-TCDYVLAAV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPRVSAEGLTPFTVTTKNENRGSPAVSYVKRV
TVTALGTNISIHKGEVGRVRV-NDVLTALPVSAAGGRISVTHGPGKAVVVTDFGLQVSYD
WDWRVEVTLPSSYHSAVCGLCGNMDQNPSNDRVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TLAP-----SVPTWGGSWRVPGW
DPFCWDEC---LGSCPTCPDDRLEEYEGPAFCGPLAPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

STGPFAACHSHVPPESFFKGCV
LDVCLGGGAHDLLCQALAAYAAACQAAGVVIGDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYELCGPPCPAS
CPSPSPPSTSAVCEGPCTEGCQCDEGFVLSAENCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADG
TCSQLCRCEH----EGGSLVCTPASCGLGEQCALLPSGQYSC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5991)

C
QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCGTL-PKGTKNFTVTVTNERLGS--QAV-SY
-----THSVTLHVYDHVLTLSASWPQQLQV--------NGVLVNLPFQPGS-HLQAYLSG
N--GVVVTTDFGLSLSLDQGSFVRLRVPAAYAGALCGLCGNYNKDASDDL

ENSGT00760000118896_8_Linker_77_82 (5991, 6056)

NAVEGNPA--
------GWQVGGDLGCG-ECVPGPCPKPCTLEEQQAFAGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
N-PEGPLAPCHTLVPP-EQYFTACLLDACQAQGHQGGLCPAVATYVAACQAAGAQIGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CSPS

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPVNSHYELCGDSCPVSCPSLSAPEG-CES--TCREGCVCNSGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYPLGATFYPGPECERHCKCGPGGEVSCQEGADCGPYEECRVENGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYVTLDGRVY-DLH-------GSCSYVLAAVCHPNPGDEDFSIVL
KKDKAGD-PQQVVVTVAGHVVSLAGGP--KVTVNGEAVNLPVA--EGHVRVTAEGRNIIL
QTSKGLRVLFDGDAHVLISIPSPFHGRTCGLCGNFNGNWTDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GEVAPSVEDFGTA
WRDPDS--SPDCSEGCGPQGCPVCLAQETAAYESSEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGRLRDPKGPFSDCHSVLNPSEY
FRQCVYDQCAEKGNIAFLCRSLAAYTAACQAAGAAVKP-WRTDTF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTHSC----QGSCAALSGLTGCSVLCFEGCECDDRFLLSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHNG
RYLPVNSTQLMSDCSECCSCSSSTGLTCKAASCPEGQVCDVQEGSWV

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CRAPSG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6818)

CSLSV
GGNLTTFDGAHSAVDSP---GIYELSSRCPGLPN-SIPWYRVLADVQTCEDNVKAVSKIH
IFFEDGMVTVTQSKGV-WVN-GQRVN---SLPADVLTSVSVKREADGSMVVSLKDGVQVR
LGSDGHLDVMVSDDHAGKLCGACGNFDGERNNDF---QGEATMKDWIPSDFSPCDN----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLRSW---------------------
------------WML---------WAGATLLWAQ-RTLEKTPCEGK-QCAARQLCKVVNG
QARCMAS-VAT

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRYYDMMGTCLYSLVELQSD--DDSLPAFSVDAKNE
HRGSRRVSYVGLVTVRAYSHAVSLARGEVGFARIDNQRSRLPASLNEGRLRVYQSGTRAV
VELD----FGLVVSYDWDAQLALSLPAHFQGQVRGLCGNYNGDPTDDFLTP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DSEQ-----
--------APDAVEFASSWKLDDGDYLCEDGCQENCPACTTDQAQLYEGSRF

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTQLN
GPFAVCHEALDPQPFLQECVYDLCVVNGDRASLCRGLSAYTQACLELGISVGNWRSSAN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPVNSRYELCAPACQASCNPDAVPSNCSARQCVEGCVCLEGFVESGGACVAASS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
IYEGRPLAPGQEVWADDTCQRRCTCDATT-GQVRCSDTQGCPTGERCLVQNGLRG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDR
FGT

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1059)

CEGSGDPHYVSFDGRRFDFMGTCTYLLAGSCGQA--SGLQTFRVLVENEHRGSQTVS
YTRAVLVEARGVKVAVRRKYPGRVLVDDILQYLPFQAADGQVQVFRQGRNAVIRTDFGLT
VTYNWDAHVTVKVPTSYAGALCGLCGNFNEDPADDLAL

ENSGT00760000118896_8_Linker_11_13 (1059, 1121)

KGGGQAA-------NALAFGNS
WQEETRP-GCGAAEPGDCPK-------LDSLVAEQLQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPSGPFRECHQTLD
PQGAVRDCVYDRCLLPGQSGPLCDALAAYADECQAAGVTVYPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPSHS---------HYEECSYGCPLSCGDLPVSGGCG-FECKEGCVCDEGFVLSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVYQGAYYPPEQTFY--PGPECDSLCYCEEGGLVSCVPSSCGPHEACQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGQRFDFMGTC-VYVLAQTCGT-RPGLPQFAVLQENV
AWGN-GKVSVTKAITVQVANFTLRLEQSQWK-VTVNGVDRRLPVVLDEGRI---HVF-QH
GSDI-VIETD-FGLR-VAYDLMYNVRVTVPGNYYQQLCGLCGNYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QAGSANEFGNSWEEAVPDSPCLPPPT--CQPGDEGCDT--ECK
PELQNKYEQQEF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLTSTTGPLAACHKLLDPQGPLQDCVFDLCLGGGNESILCSNIQAY
VSACQAAGGHVEPWRTESF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------MP

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPANSHYELCADTCSL
GCSALSAPPQCPESCAEGCQCDSGFLSDGQGCVPIQE

ENSGT00760000118896_8_Linker_24_23 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_23 (1719, 3848)

GCYHNGIYYEPEKVVLTDNCQ-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------Q------------------------------------
-------------------Q----------------------------------------
--------------C---------------------------------------------
-------V--------------------------------------------------C-
------------------------------------------------Q-----------
----------------------------------------P-------------------
--------------------------------G---------------------------
--------------------K---------------------------------------
-----G-------------------------------------------------L----
---------------------------------------------------V--------
-------------------------------------------C----------------
-----------------------------------Q------------------------
-----------------------------N------------------------------
-----------------------H------------------------------------
-------------------S----------------------------------------
-------------C----------------------------------------------
-----D-----------------------------------------------------A
----------------------------------------------G-------------
------------------------------------Q-----------------------
----------------------------V-------------------------------
-----------------------C------------------------------------
---------------Q--------------------------------------------
------P-----------------------------------------------S-----
----------------------------------------------G-------------
----------------------------------G-------------------------
------------------------V-----------------------------------
------------------L-----------------------------------------
-------------S----------------------------------------------
-------C----------------------------------------------------------V-------------------------------------------T---------------------------------------K---------------------------------D---------------------------------P---------------------------------C------------------------------------------H---------------------------------S---------------------------------V----------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------C-----------------------------------R----------------

PF12714 // ENSGT00760000118896_8_Domain_34 (1719, 3848)

GCYHNGIYYEPEKVVLTDNCQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------Q------------------------------------------------------C----------------------------------------------------V--------------------------------------------------C-------------------------------------------------Q---------------------------------------------------P---------------------------------------------------G-----------------------------------------------K--------------------------------------------G-------------------------------------------------L-------------------------------------------------------V---------------------------------------------------C---------------------------------------------------Q-----------------------------------------------------N-----------------------------------------------------H-------------------------------------------------------S-----------------------------------------------------C---------------------------------------------------D-----------------------------------------------------A----------------------------------------------G-------------------------------------------------Q---------------------------------------------------V------------------------------------------------------C---------------------------------------------------Q--------------------------------------------------P-----------------------------------------------S---------------------------------------------------G-----------------------------------------------G-------------------------------------------------V-----------------------------------------------------L------------------------------------------------------S-----------------------------------------------------C----------------------------------------------------
------V-------------------------------------------T---------
------------------------------K-----------------------------
----D---------------------------------P---------------------
------------C------------------------------------------H----
-----------------------------S------------------------------
---V----------------------------------T---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------C--------------------
---------------R--------------------------------------P-----
----------------------------Q-------------------------------
---E---------------------------------T----------------------
------------C----------------------------------Q------------
-----------------------N----------------------------------K-
---------------------------------------------N--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------GQGVCVPNYQAT

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYHSFDGWNFDFQGTCNYVLAST-DCPGSNAQGLTPFTVTTKNENRGNPSVSYVRLV
TVTTLNTNISIHKGEIGKVRV-NGVLRALPVSLADGRLSVTHGASKAVLATDFGLQVTYD
WDWRVEVTLPSSYHGAVCGLCGNMDRNLSNDQAFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5619)

TLAP-----SIPIWGGSWRVPGW
DPLCWDEC---QGSCPTCAEDRLEEYGGPGFCGPLAPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

SGGPFAACHDHVAPDNFFKGCV
LDVCLGGGAKDILCQALAAYAAACQAAGIVIKDWRTEAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CELP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYELCGPPCPAS
CPSPTPPTSPAICEGPCVEGCQCDSGFVLSVDHCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

EGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADA
TCSQRCQCGP----GGGSLVCKPASCGLGEECALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5992)

C
QAWGDPHYITLDGHRFDFQGACEYLLSAPCHDP-PEGAENFTVTVANEHRGS--QAV-SY
-----TRTVTLHIYGHSFTLSAGWPRQLQV--------DGKLVALPFQLDS-RVHAYLSG
A--DVVVTTASGISLAFDGDSNVRLRVPAAYAGSLCGLCGNYNKNPNDDLN

ENSGT00760000118896_8_Linker_77_82 (5992, 6056)

AVEGKPD--
------RWQVGGAAGCG-ECVPGPCPTPCTPEQQEPFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
S-PEGPLAPCHSLIPP-EQYFQACLLDACQAQGHPGGLCPAVAAYVAACQAAGAQLGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYQLCGDSCPVSCPSLSAPEG-CES--TCREGCVCDAGFVLSGDSCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHEGRYYPLGETFYPGPECGRHCQCGPGGQVSCQEGETCRPYEECRVQDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

RPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYITLDGRVY-DLH-------GSCSYILAKVCHPQPEDEDFTIVL
EKNAAGD-PQRVVVTVAGQVVSLARGP--QVTVDGEAVALPVA--VGHVRVTAEGRNMVL
QTTKDLRLLYDGDAHILISIPSPFHDRLCGLCGNFNGNWNDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GATAPSVDAFGAA
WQAPG-S-SQGCSEGCGPQGCPVCSAEQTAPYESLEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLKDTNGPFSACHAALSPSEY
FRQCVYDLCAQKGNVTYLCRSLAAYTAACQAAGMAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAN
SHYSVCTRSC----QGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHDG
RYLPVNSSLLTSDCSQRCSCSSSTGLTCQAASCPPGRVCDVQAGVRD

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWTPHG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6814)

CSLSV
GANLTTFDGAHSAVSSP---GVYEISFRCPGSQE-SIPWYRVVADVQPCKGKVEAVALVH
IFFQDGLVTVTQNKGV-WVN-GLQV----DLPAEVLTSVSVSQNPDGSVLVQQKEGVQVQ
LGTNGQLAVVVSDDHAGKLCGACGNFDADWSNDWPNS-QETTLENWKAPDFSPW------
-

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---

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSYGCPLSCGDLPVRGGCG-SECHEGCVCDEGFALSGES
CLPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYHPPGQTFY--PGPGCDSLCHCQEGGLVSCEPSSCGPHEACQPSGG
SLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGRRFDFMGTC-VYVLAQTCGT-RPGLHQFAVLQENV
AWGN-GRVSVTRVITVQVANFTLRLEQKQWK-VTVNGVDMKLPVVLANGQI---RAS-QH
GSDV-VIETD-FGLR-VAYDLVYYVRVTIPGNYYQLMCGLCGNYNGDPKDDFQKPN

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QAGNANEFGNSWEEVVPGSPCLPPPT--CPPGSEGCDTSSECP
PEQEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLSSPTGPLASCHKLVDPQGPLQDCVFDLCLGGGNLSILCSNIHAY
VSACQAAGGHVKPWRTESF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------MK

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPANSHYELCADTCSL
GCSALSAPLQCPDGCAEGCQCDAGFLYNGEACVPIQQ

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1772)

GCYHNGVYYEPEQTVLIDDCRQ
QCTCHAGKDVLCQEHSCKPGQVCQPSEGVLSCINK--DPCDGVTCRPQ-------E-T-C
--K-E-Q-G-G-Q-G-V-C-V-PS-Y-E-A-T-C

PF00094 // ENSGT00760000118896_8_Domain_31 (1835, 2340)

-WL-W-G-DPHYH-S-F-D-GR-P-F
-D-F--Q-G-T--C-N-Y-V-L-A-T-T-G-C-P-GV-N-T-Q-G-LTPF-T-V-T-T-K
-N-E-N-R-G-N-PA-V-S--Y-V-R-V-V-T-V-A------------------------
--------------------------------A--L--G--T--N-I--S----I--H--
K----G--E--I--G--K--V---R--V--N--G--V--L--T--A--L-----------
------------------------------------------------------------
----PV-S-EA-N-GR-I-SV-TH-GA-S-KA-LL-V-----------------------
-----------AD-F-G-LQ-VS-Y-DW-N-WR-V---------------D-V-TL-P-S
S-Y-HG-AV-CG-LCG-NM-DR-NP-S-ND-QV-FP-NG--------------------

ENSGT00760000118896_8_Linker_31_32 (2340, 2436)

T
-L-AP-SI-PI-WG-G-SW-R-V----------P-GW-DP-L-CWD-VC-PG-SCP-TCP
-EDK-LE-QY-EG-PG-FC-GP-LVP------GTG

PF08742 // ENSGT00760000118896_8_Domain_32 (2436, 2555)

-G-PI-AT-CH-AHV-P-PE-SF-F
K-GC-VL-DV-CM-GG---G---------A-HD-I-LC-KA-LA-SY-V-AA-C------
----------Q-A-AG-VV-I-ED-WR-AQ-VG-

ENSGT00760000118896_8_Linker_32_33 (2555, 2561)

CE-IT-

PF01826 // ENSGT00760000118896_8_Domain_33 (2561, 2635)

CPD-NS-HYE-VC-GPP-CP
A-SCPS-PAP-PET-PA-ACEG-PCVE-GCQ-CDA-G-FVL-SA-DR-CV-SL-

ENSGT00760000118896_8_Linker_33_34 (2635, 2640)

NNS-C

PF12714 // ENSGT00760000118896_8_Domain_34 (2640, 2794)

G
C-WANG-TY-HE-AG-SEF-WA-DG-TC-S---------H-RC-RC-GPG-GG-SLV-CT
P------AS-CG-----------------------------------LG-EV-CG-L-LP
-----------------------S-GQ-H-GC-

ENSGT00760000118896_8_Linker_34_23 (2794, 2804)

QP-VS-TA-E

PF00094 // ENSGT00760000118896_8_Domain_23 (2804, 3177)

CQ-AW-GD-PH-YV-TL
-DG------------------------HR-F-DF-QG-NC-EY-LL-S-AP-CH-GP---
---------P-S-GA-AN-F-TV-T-VA-NE-HR-GS-QA-V-S----------------
----Y-T-R-SV-TL-Q-IY-N-HS-LT-L-SA-RW-P-RR-LQ-V-DG-V-FV-A-L-P
-FH-L-DS-L-LH-A-HL-SG-AD-VV-V-TT-TS-GL-T-LT-FD-GD-S-FV-RL-RV
-PA-AY-AG-AL-CGL-CG-NY-NQ-DP-A------------------------------
---D-DL-KA-V------------------------------------------D-

ENSGT00760000118896_8_Linker_23_37 (3177, 3233)

G-KP
A-AWQ-VG-GAP-GCG-EC-V-SG-PC-PSQ-CT-PE-QQE-SF-AGP-DA-

PF08742 // ENSGT00760000118896_8_Domain_37 (3233, 3432)

CGV-IS-A
T-DG-PL-A--------------PC-HG-LV-PP-AQ-YF-QG-CL-L------------
----------------------D-AC-QV-QG-HP-GG----------------------
-----LC-PA-VA-AY---VA-AC-QA-AG-AQ-LG-EW-R-RP----------------
--------DF-C------------------------------------------------
------------------------------------------------------------
--------------H-----------D

PF12714 // ENSGT00760000118896_8_Domain_52 (3568, 3680)

-DR-YY-PL-GQ-TF-YS-GPGC-DS-LCH-CR
-E----------------G-GL-VSC-QPS-SC-GPH-ETC-QP-SG-G-----------
---------------S-LG

ENSGT00760000118896_8_Linker_52_27 (3680, 3692)

C-VA-VGS-AT-

PF00094 // ENSGT00760000118896_8_Domain_27 (3692, 4032)

CQ-AS-GD-P-------------------
------------H-YT-TF-DG-R-RF---------------------------------
-------------D---------------------------------FM-GT-C-VY-VL
---AQ-TC-GT-RP-G-LH-R-FA-V-LQ-EN-V-AW-----------G-NG-R-V-SV-
T-R-V-I----------TVQVANFTLRLE---------------QRQWKVTVNGVDMKLP
VVLANGQIRASQHGSDVVIET-----DFGLRVAYDLVYYVWVTIPGNYYQLMCGLCGNYN
GDPKDDFQKPN

ENSGT00760000118896_8_Linker_27_55 (4032, 4107)

GSQAGNANE------FGNSWEEVVPGSPCLPPPTCPPG-----------
-SEGCDTSS--ECPPEQEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_55 (4107, 4243)

CGL---------------LSSPTGPLASCHKLVD
PQGPLQD---------------CVFDLCLGGGNLSILC-------------------SNI
HAYVSACQAAGGH--------------------VKPWRTESF

ENSGT00760000118896_8_Linker_55_56 (4243, 4260)

CPMK-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4704)

C
PANSHYELCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSALSAPL--QCPDGCA
------------EGCQCDAGFLYNG-----------------------------------
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-

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-----------------------------------------MLIIALPAA----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPNS---------HYEACSRGCPLSCGDLPVPGGCG-SDCHEACVCDEGFALSGES
CVPLPS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCTYQGVYYPPGQTFR--PGPGCDSLCQCQEGGLVSCNPSSCGPHEACQPSGG
ILD

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVVVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1498)

CQASGDPHYTTFDGRRYDFMGTC-VYVLSRTNVT-RPGLQQFAVLQENA
AWGN-GRVSVTRVITVQVANFTLVLKQNHWK-VTVNGVDMRLPVVLAQGRI---RAS-QH
GSDV-VINTD-FGLR-VAYDLVYNVRVTVPGNYYQQLHGLCGNYNGDSKDDFQKPDG

ENSGT00760000118896_8_Linker_19_22 (1498, 1567)

S--
-----------------QAGSSTDFGNSWEEAVPGSPCLPPPT--CKPGE-DCNSSPECP
PELQEK

PF08742 // ENSGT00760000118896_8_Domain_22 (1567, 1643)

YKQEKFCGLLTSPNGPLAACHKLVDPQGPLKDCIFDLCLGGGNESILCSNIHAY
VSACQAAGGDIEPWRTESFC--

ENSGT00760000118896_8_Linker_22_24 (1643, 1665)

P-------------------ME

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPPNSHYEVCADTCSL
GCSALSAPPQCPESCAEGCQCDPGFLNDGLACVPIQQ

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1772)

GCYHNGIYYEPNQTILTDNCQQ
QCVCHAGQGVVCQAHSCKPGQVCEPSGGILSCVTK--DPCHGVTCRPQ-------E-T-C
--Q-E-K-D-G-Q-A-V-C-V-PN-Y-E-A-T-C

PF00094 // ENSGT00760000118896_8_Domain_23 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GW-E-F
-D-F--Q-G-T--C-D-Y-V-L-S-A-A-G-Y-Q-GG-R-T-Q-S-LTPF-T-V-T-T-K
-N-E-N-R-G-N-PA-V-S--Y-V-R-L-V-T-V-S------------------------
--------------------------------A--L--G--F--N---------------
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--------ISIHKGEVGKVRV-NGVLTVLPVSVAGGRLSVTHGPSKALLVADFGLRVTYD
WDWRVEVTLPSSYHGQVSGLCGNMDQNISNDRVFPNG

PF00094 // ENSGT00760000118896_8_Domain_27 (1835, 5558)

-WL-W-G-DPHYH-S-F-D-GW-E-F-D-F--Q-G-T--C-D-Y-V-L-S-A-A-G-Y-Q-GG-R-T-Q-S-LTPF-T-V-T-T-K-N-E-N-R-G-N-PA-V-S--Y-V-R-L-V-T-V-S--------------------------------------------------------A--L--G--F--N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISIHKGEVGKVRV-NGVLTVLPVSVAGGRLSVTHGPSKALLVADFGLRVTYDWDWRVEVTLPSSYHGQVSGLCGNMDQNISNDRVFPNG

ENSGT00760000118896_8_Linker_27_74 (5558, 5607)

TLAP-----SIPSWGGSWRVPGW
DPLCWDEC---QGNCPTCPEDRLEEY

PF08742 // ENSGT00760000118896_8_Domain_74 (5607, 5681)

KGPGFCGPLAPDSGGPFAACHAHVAPDSFFKGCV
LDVCLGGGAHDILCQALAAYAAACQAAGIAIKNWREEAGC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

EIS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5737)

CPENSHYELCGPACPAS
CPAPTPPTTPKPCDSPCAEGCQCDSGFVWSADRCVP

ENSGT00760000118896_8_Linker_75_76 (5737, 5742)

LDGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYHEAGSEFWADA
TCSQRCHCGP----GGSSPICKPAKCGLGEQCALLPSGQLGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5991)

C
QAWGDPHYVTLDGHRFDFQGNCEYLLSTPCKAL-PTGAENFTVTVVNEHRGS--QAV-SY
-----TRSVTLHIYSHSLTLSAQWPRQLQV--------DGKLVALPYQLDS-RLRAYLSG
A--DVVVTTAAGLSLAFDGDSFVRLHVPAAYAGALCGLCGNYNQDPADDL

ENSGT00760000118896_8_Linker_77_82 (5991, 6041)

EAVGGNPA--
------GWQVGGEAGCG-ECVPGPCPPQCTPEQQEPFGGP

PF08742 // ENSGT00760000118896_8_Domain_82 (6041, 6126)

DA-------------CGIIS
A-PDGPLAPCHALVPP-QQYFQACLLDACQAQGHPGGLCPAVETYVAVCQAAGAQLGEWR
RPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PIQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYKLCGDSCPISCPSLSAPEG-CVQ--TCREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHEGHYYPLGESFYPGPECERRCKCGQGGQVTCQEGSACRPYEECRVEDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CVINGGIHYITLDGRVY-DLH-------GSCSYVLARVCHPDPKDEDFAIVL
EKDAAGD-LQQLVVTVAGQVVTLAQGP--KVTVDGEAVALPVA--VGHVRVTAEGRNVIL
QTTKALRLLFDGNAHIFISIPSPFRGRLCGLCGNFNGNWSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6453)

GAEASSVDAFGAA
WRAPS-S-SQGCTEGCGASGCPVCSAQETAPY

PF08742 // ENSGT00760000118896_8_Domain_88 (6453, 6527)

ESNQACGQIRDPNGPFAGCHAVLNPSEY
FRQCVYDLCHHKGSTAFLCQSLAAYTAACQAVSGTVKP-WRTESFC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSTCMRSC----QGSCAALSGLTGCTNRCFEGCECDDRFLLSQGTCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHDG
HYLPVNSSLLSSDCHQRCSCSSSTGLTCQAASCGPNSVCEVQAGARN

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWTPQG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6813)

CSLSV
DANLIIFNGSRRAFHSQ---GIYELSSLCPGLPDTTIPWYRVVAVLHACKDKVEPVDEVH
IFFKDGLVTLSLEKGV-WVN-GLPV----TLPAELSASVSIRKNPDGSVSVIQKAGVQVW
LGTNGQLAVMVNDDHAGKLCGVCGNFDKAQTNDGHDSRR---------------------
-

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MA

PF00094 // ENSGT00760000118896_8_Domain_4 (520, 652)

ELCGN--DETLPAFSVEAKNE
HRGSRLVSYVGLATVRAYSHAVSLARGEVGFARIDNQRSRLPVSLAEGRLHVYQSGTQAV
VELD----FGLVVTYDWDAQLALSLPKRFQDQVCGLCGNYNGDPADDFLTS

ENSGT00760000118896_8_Linker_4_8 (652, 713)

NWEQ-----
--------TSDAVEFASSWKLDDEDYLCEDGCQNNCPACTPDQTQHYEGSRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGILTQPN
GPFAACHGALDPQPFLKDCVYDLCVVNGERVSLCRGLSAYAQACVELGISVGDWRSPAS

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYQLCAPACPDSCNPTAVPSNCSERPCVEGCVCLPGFVASGGACVSASS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TFEGRLLAPGQEVWADKYCQRRCTCDGGT-GQVRCSDTQGCPSGERCRVQNGFLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDR
FGT

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQGSGDPHYVSFDGRRFDFMGTCTYLLAGSCGQA--TGLPAFRVLVENEHRGSQTVS
YTRAVRVEARGVKVVVRREYPGRVLVDDILQYLPFQAADGQVQVFRQGQDAVVRTDFGLT
VTYNWNAHVTAKVPGSYSGALCGLCGNFNGDPADDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

GGGQAA-------NALAFGNS
WQEETRP-GCGATNPGDCPN-------LDSLVAQQLQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPNGPFRDCHNTLD
PQGVVRDCVYDLCLLPGQSGPLCDALASYAAACQAAEATVYPWRNEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEECSYGCPMSCGDLPVLGGCG-YNCKEGCVCDEGFVLDGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVYQGAYHPPGQTFH--PGPGCDSLCHCEEGGLVSCEPSSCGPHEACQPSSG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGRRFDFMGTC-VYALARTCGT-RPGLAQFAVLQENV
AWGN-GKVSVTKAITVQVANFTLRLEQNQRK-VTVNGVDVRLPVVLANGQV---HAF-QH
GSDV-VIETD-FGLR-VAYDLQYNVRVTVPGNYYQQLCGLCGNYNDNPKDDFQKPD

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QAGSPNEFGNSWEERVPDSPCLPPPT--CAPGG-DCEPEPECK
PELEEKYKQEKF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLTSSTGPLAACHKLLDPQGPLQDCVFDLCLGGGNESILCSNIHAY
VSACQAAGGQVEPWRTESF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------MP

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CHPNSHYELCADTCSL
GCSALSAPPQCPETCAEGCQCDSGFLNDGKGCVPIQE

ENSGT00760000118896_8_Linker_24_23 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_23 (1719, 3848)

GCYHNGVYYEPEQTVLIDNCQ-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------Q------------------------------------
-------------------Q----------------------------------------
--------------C---------------------------------------------
-------V--------------------------------------------------C-
------------------------------------------------H-----------
----------------------------------------A-------------------
--------------------------------G---------------------------
--------------------K---------------------------------------
-----G-------------------------------------------------M----
---------------------------------------------------A--------
-------------------------------------------C----------------
-----------------------------------Q------------------------
-----------------------------D------------------------------
-----------------------H------------------------------------
-------------------S----------------------------------------
-------------C----------------------------------------------
-----E-----------------------------------------------------P
----------------------------------------------G-------------
------------------------------------Q-----------------------
----------------------------V-------------------------------
-----------------------C------------------------------------
---------------Q--------------------------------------------
------P-----------------------------------------------S-----
----------------------------------------------E-------------
----------------------------------G-------------------------
------------------------V-----------------------------------
------------------L-----------------------------------------
-------------S----------------------------------------------
-------C----------------------------------------------------------I-------------------------------------------T---------------------------------------K---------------------------------D---------------------------------P---------------------------------C------------------------------------------H---------------------------------G---------------------------------V----------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------C-----------------------------------R----------------

PF12714 // ENSGT00760000118896_8_Domain_34 (1719, 3848)

GCYHNGVYYEPEQTVLIDNCQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------Q------------------------------------------------------C----------------------------------------------------V--------------------------------------------------C-------------------------------------------------H---------------------------------------------------A---------------------------------------------------G-----------------------------------------------K--------------------------------------------G-------------------------------------------------M-------------------------------------------------------A---------------------------------------------------C---------------------------------------------------Q-----------------------------------------------------D-----------------------------------------------------H-------------------------------------------------------S-----------------------------------------------------C---------------------------------------------------E-----------------------------------------------------P----------------------------------------------G-------------------------------------------------Q---------------------------------------------------V------------------------------------------------------C---------------------------------------------------Q--------------------------------------------------P-----------------------------------------------S---------------------------------------------------E-----------------------------------------------G-------------------------------------------------V-----------------------------------------------------L------------------------------------------------------S-----------------------------------------------------C----------------------------------------------------
------I-------------------------------------------T---------
------------------------------K-----------------------------
----D---------------------------------P---------------------
------------C------------------------------------------H----
-----------------------------G------------------------------
---V----------------------------------T---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------C--------------------
---------------R--------------------------------------P-----
----------------------------Q-------------------------------
---E---------------------------------T----------------------
------------C----------------------------------K------------
-----------------------E----------------------------------K-
---------------------------------------------D--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------GQGVCVPNYEAT

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYHSFDGWNFDFQGTCNYVLAST-SCPGISAQGLTAFTVTTKNENRGNPAVSFVRLV
TVTTLNTNISIHKGEIGKVRV-NGVLTALPVSEAGGRLSVTHGASKAVLATDFGLQVSYD
WDWRVEVTLPSSYHGAVCGLCGNMDRNPSNDQAFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5619)

TLAP-----SIPIWGGSWRVPGW
DPLCWDEC---QGSCPTCSEDNLEKYEGPSFCGPLVPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

TGGPFADCHAQVAPESFFKGCV
LDVCLGGGAQDILCQALAAYAAACQAAGVVIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEMS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPSPAPPTTPAPCEGPCAEGCQCNSGFVWSASHCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADA
TCSQRCQCGP----GGGSLVCKPASCGLGEECALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

HPIST----------VE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5990)

C
QAWGDPHYITLDGHRFDFQGSCEYLLSAPCQGP-PAGVENFNVTVENEHRGS--QAV-SY
-----TRTVTLHIYGHSFTLSARWPRQLQV--------DGKLVALPFQLDT-RLHSYVSG
P--DVVVTTTSGISLAFDGDSNVRLRVPAAYAGALCGLCGNYNQDPKDD

ENSGT00760000118896_8_Linker_77_82 (5990, 6056)

LNAVGGNPA--
------GWQVGGAEGCG-ECVPGPCPEPCTPEQQEPFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-PDGPLSPCHSLVPP-AQYFQACLLDACQAQGHPGGLCPAVAAYVAACQAAGAQLDEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYKLCGDSCPVSCPSLSAPEG-CEP--TCREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6241)

GCLHEGRYYPLGEAFYPGPECGRRCECGPGGQVTCQEGAACRPYEECRLQDGVQA

ENSGT00760000118896_8_Linker_84_85 (6241, 6249)

CYPIGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGTHYITLDGRVY-DLH-------GSCSYILAQVCHPQPGDEDFAIVL
EKNAAGD-PQRLVVTVADQVVSLAPGP--QVTVDGEAVALPVA--VGHVRVTAEGRNVIL
QTTKDLRLLFDGDAHILISIPSPFHGRVCGLCGNFNGNWSDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GAVAPSVDAFGAA
WRVPG-S-SQSCSEGCGPAGCPVCLAEETAPYESLNA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGRLRDPNGPFSACHAVLGPSEY
FRQCVYDLCAHKGNSTFLCRSLAAYTAACQAAGSAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTRSC----QGSCAALSGLTGCTTRCFEGCECDDRYLLSQGICIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCSHDG
RYLPANSSLLTPDCSKRYSCSSSTGLTCQEVSCPPGRICEIQAGAWD

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWVPQG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6819)

CSLSV
DANLTTFDGARSAVHSP---GVYELSHRCPGLRE-AIPWYRVVADVQPCSGKAEAVGLVH
LFFQDGLVTVTRKKGV-WVN-GLQV----SLPAEVLTSVFVHRNPDGSVLVQQKAGVRVR
LGTDGQLAVMVSDEHAGMLCGACGNFDADQTNDGLGSQGKATLEDWRAQDFSPCLN----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLWSWWAL----------W-------
--------------------------AGATLLWARLSPAEASCQGI-QCTSGQRCQMVSG
KARCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELSGE--DETLPAFSVEAKNE
HRGSRQVSYVGLVTVYAYSHSVSLVRGETGFARIDNQRSRLPASLSDGRLRVYQSGTRGV
IELD----FELVVTYDWDCQLTLSLPKRFQNQVWGLCGNYNGDPADDFLTPD

ENSGT00760000118896_8_Linker_4_8 (653, 713)

GEQ-----
--------APDALEFANSWKLDDGDYLCDDGCHTTCPSCTAGQTQHYKGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLST
GPFSACHEFLDPKPFLEDCVFDLCVTGGERLSLCRSLSAYAQACAELGVSLGNWRSPSN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSCYDPCSPACPASCNSEAAPANCSERPCVEGCVCLPGFVASGGDCVPVSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TFQGRPLAPGQEVFADDLCRQRCTCDAAT-QKVICRDTSGCPSGERCRVLNGLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYVSFDGRRFDFMGTCAYLLVGSCGQD--AALPDFKVLVENEHRGSQTVS
YTRAVRVVARGVEVAVRRRHPGRVLVDGVLQYLPFQAAGGQVQVFRQGNDAVVRTDFGLT
VTYNWDARVTAKVPSSYAKAVCGLCGNFNGDPSDDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

GGGQAT-------SALDFGNS
WQEEVIP-GCSATDPGDCPQ-------LDSLVTQQQQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPEGPFRECHKLLD
PQGALRDCVYDLCLLPGQPKPLCDALAAYAAACQAAGGTVHPWRSETL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LA

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEPCSYGCPLSCGDLPVSQGCG-TECRESCVCDEGYALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYHPPGETFY--PGPGCDSLCHCQEGGLVSCEPSSCGPHEACQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGTTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYITFDGRRFDFMGTC-VYVLAQTCGT-RPGLHEFTVLQENE
AWGN-GQVSVTKAITVLVANHTLRLEQNQWK-VKVDGVDMKLPVVLDGGKI---RVS-QH
GSDV-VIETD-FGLR-VVYDLVYYVRVTIPGNYYQQMCGLCGDYNGDSKDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAANPSDFGNSWEEAVPDSPCAPV-P--PCT-GDSCGT--ECS
PELKDKYHGVQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLTS------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------PTGPLAACHKLLD
PQGPLED---------------CVFDLCLGGGNLSILC-------------------NNI
HAYVSACQAAGGE--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPMK-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCWALSTPQ--QCPE---
---------VCAEGCECDSGFLYNGK------ACVPI----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGVYYEPEESVL
IE----------------------NCQQQCVCHPGKG----------------------M
VCQDHSCKPGQVCEPSGGI------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCHGVTCWPQETCK-----------VQG
GQGVCVPNYNST

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------NFDFQG-TCSYLLAGT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------HCPGVSAEGLTPFTVITKNENRGNPTVSYVRLV
TVTALNVNISIHKNEIGKVRV-NGVLKALPVYLAGGQISVVHGGSKAVLVTDFGLQVTYD
WNWRVEVTLPSSYHGAVCGLCGNMDKNPQNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TAAP-----SIPTWGGSWQIPGW
DPLCWNEC---QGSCPMCPEDQVEKYEGPGYCGPLAPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

TGGPFASCHAHVPPESFFKGCV
LDVCLGGGNKDILCQALASYAAACQAAGIEIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPARHTTPAACDGPCVEGCQCDQGFVLSAEQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEPGTEFWTDA
TCSKRCHCGP----GGESLVCTSASCGLGEECALLPSGQLGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5992)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCHAP-PTGTEYFNVTVINEHRGS--QAV-SY
-----TRTVTLNIYGLSLTLSARWPRQLQV--------NGEFVALPFHLDQ-RLSIYLSG
A--DVVVNTAFGLSLAFDGDSFVRLRVPAAYAGALCGLCGNYNKNPNDDLT

ENSGT00760000118896_8_Linker_77_82 (5992, 6056)

AVAGKPE--
------GWKVGGTPGCD-QCVTEPCPQPCTPEQQEPFRGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIS
S-PEGPLAPCHSLVPP-TQYFEACLLDACQVQGHPGGLCPAIAAYVAACQAAGAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYQLCGDSCPVSCPSLLPPEG-CET--TCREGCVCDSGFVLSGDACV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHNGRYYLLGATFYPGPECERLCECGPGGQVSCQDGADCEPYEECRIENGIQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGH

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CLANGGIHYVTLDGRVY-DLH-------GSCSYVLAQVCHPKPGEEEFSIVL
EKNSAGD-PQRVVVTVDGQNVVLAKGP--QVTVDGETVVLPVT--KGHVSVTAEGRNMVL
QTSKGLKLLFDGDAHILMSIPSPFRGRICGLCGNFNGNWSDDFVLPDG

ENSGT00760000118896_8_Linker_85_88 (6409, 6458)

TVAPSAEAFGAE
WRAPSS--SLGCGEGCGPQGCPVCLAEETKSYEKNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKIRDPQGPFKDCHQVLSPLEY
FRQCVYDLCAHKGNKTYLCRSLAAYTAACQAAGATVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPDH
SHYSVCMSSC----QGSCAALSGLTQCTTRCFEGCECDNHYLLSQGVCIPAHD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTYNG
QYMPVNTSLMTSDCSELCCCSSRTGLTCHAAGCPSGQVCELQGGVRKC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QPARG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6817)

CSISV
GANLTTFDGAHNAISSP---GVYELSSRCPGLQK-TVPWYRVVADVQPCHGNDNVVDKVH
IFFEDGIVTVTQSKGV-WVN-GLRV----DLPANVLTSVSVSKMPDGSMLVHQKAGVQVR
LGINGQLDVMVGDDHAALLCGACGNFDGDQKNDVLGS-----QEKWKAQDFSSCSN----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGPLWSWWAL----------W-------
--------------------------AGAALLWARLSPGEASCQGI-QCTSGQRCQMVSG
KARCVAESIAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELRST--NKSLLAFKVEAKNK
NRSTNKVSYVRLVTVHVYNHTVSLEYGEIGIARIDYQYSSLPASLSEGRLRVYQSGTQGV
IELD----FGLVVTYDWDGRLTLSLPKRFQDQVSGLCGNYNGDPADDFLTPDG

ENSGT00760000118896_8_Linker_4_8 (654, 713)

KQ-----
--------ASDVLNFTKSWKLDDGDHLCDDGCYGNCPSCTASQSQFFKGDLF

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGLLTLSM
GPFADCHGFLDPKPFLEECVYDMCVTGGERLTLCNGLSAYARACVDLGIPVREWRSRSN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSHYELCSPACPASCNSEALPTNCSGRPCVEGCVCLPGFMANRGHCVPVSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TFQGRLLAPGQEVFADDLCRQRCTCDGAT-QKVICQDTPGCLPGERCGVQNGFLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPEY
FRS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYMTLDMRNYNFMGTCTYMLVASCGQH--PSLPEFKVVMENERRGSQSVS
FVYSVQLEVYGVKLEVPRDYPGKVLMDGISLHLPFQAARGKVVVFRQGKYATLRTDFGLT
VSFNWDTHVTAKVPSNYAKAVCGLCGNFNGDPRDDLGLQ

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

SKGEAL-------DPRDFGRK
WLVTAKP-SCRTDEQHVCPD-------INSKVVA--ENRK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

KCHILGDQNGQFRDCRRVST
FNNALMECIYDSCRMRGQTKPLCDTLSTYTTICQAEGVTVYPWRSEKL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-MN

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCQRGCPLTCGDLPVPGGCG-SDCHEACVCDEGFVLSGET
CVPLSS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVYRGIYHPVGDDFY--PGPECNSLCHCYKGGLVSCQPSYCSPHEVCKLSSG
ILR

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAEDSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQVSGSSHYTTFDDRRFDFLSSC-VFVLAQTCWT-RPGLQQFTILQENT
AWGNNKQLSVIKTITVQVDNYTLQLEQNQWK-VKVNGVDMKMPVLLDDNSV---QAF-QH
GIDV-VIKTK-FGLL-VSYDLNNNVRVTIPHNYYKHMCGLCGDYNDDPKNDFQKSD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAASPTELGNSWQHAVPDSPCILPPA--CKPGQD-CKP--TCS
PELENKYGGVQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLAS------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------PTGPLAACHKLLD
PQGPLKD---------------CVFDLCLGGGNQSILC-------------------DNI
HAYVSACQAAGGK--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPMV-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCSTITTPI--ACPD---
---------TCAEGCECDNDYLLGIT------GCVPM----EK

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCHYNGVFYEPEESVL
IE----------------------NCQQQCVCHAGEG----------------------M
VCKGHSCKPGQVCEPSGGV------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDLCQGVTCRSQETCT-----------VKN
GKGVCTPNYEAK

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CRVWGDPHYQSFDGL----------------NTNFHG-TCNYLLAGS-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VCPGLSANGLTPFTVATKHESQGNPAVSNVRRV
TVTTYNSSIGIHKKGIGRVQV-NGVLQNLPVYLAGGRISVVHGGSKVVLQTDFGLQVTYD
WNWRVEVTLPSSYHGAVCGLCGNMDKNPQNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5612)

TVAP-----SIPIWGGSWQIPGW
DPLCWHEC---QGSCPMCPEDRMEEYEGPGY

PF08742 // ENSGT00760000118896_8_Domain_74 (5612, 5680)

CGPLAPDTGGPFSNCHAHVPPESFFKSCV
LDICLGGQVKDILCQALSSYAAACQAAGIRIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPARHTAPAACDGPCVEGCQCDQGFVLSAEQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYHEAGTEFWTDA
TCSKKCHCGP----GGDSLVCTSASCRPDEECALLPSGQLSC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTSI----------AM

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
LILGDPHYITLDGHQFDFQGTCEYLLSAPCQEP-PTGTEYFKVTVTNEHRGS--QAI-SY
-----TRLITLHIYGLSLTLSAQWPRRLQV--------NGEMITLPFHLDS-RLLAHLSG
S--GVVVNTTSEVSLVFE-DNFVRLYVPAAYAGALCGLCGNYNKNPNDDLKAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPE--
------GWKVGGAPDCD-QCVTGTCPKPCTPEQQEPFRGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIS
A-PKGPLAPCHSLVPP-TQYFEACLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYELCGDSCPVSCPSLEAPKC-CET--TCREGCVCDSGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLYNGRYYLLGATFYPGPECEWFCECEADGHVTCQI-ETCGIHEECQLVDGIRA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6255)

HAKSSKLMLVLDG

PF00094 // ENSGT00760000118896_8_Domain_85 (6255, 6409)

VHFATPDGLVY-DLH-------GSCSYILAQVCYPKPGDEEFSIVL
EKNLAGE-PQRLVVSVASHVVVLAQGP--QVTVDSESVTLPVV--VSSLYITIESRNMLL
QTKRGLKILFDGDNHILMSIPSPFHGRLCGLCGNFNGNQSDDLMLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6458)

TLAPNVQAFGAA
WRAPGS--LLGCGEGCGPQGCPVCLAEKREAYEKNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGLLWNPNGPFADCHQVLNTTEY
FHQCVFELCAHKGNQVYLCRSLAAYTAACQAAGATVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTGSC----QGSCAALAGLTQCTTQCFEGCECDDYFLLSQGVCIPAHD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTYNG
RYMPVNTSLMTSGCTKRCICSPRTGLTCHAAGCPSGRVCEIRAGVRD

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWPAKG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6820)

CSLSM
GSNLVTFDGAHSVISSP---GVYELSSRCPGLQK-TVPWYRVVADVQSCHGNDKVLSKVH
IFFQDGIVTVSQSKGA-WVN-GLRV----DLPAQVLTSVSVRRLPDGSVLVHQKAGVQVW
LGTDGQLNVMVGDDHVALLCGACGNFDGYPNNDIRQSQGKTPMEKWRAQDFSPW------
-

MGSLRSWWLLWAGATLLWGLTQEASVDPKNSGGEEFLTAFLQNYNRGYSKAYLYLLLSSL
SDN-------LTSVSILSQVDGTSQKVTVRPGQSVMVNITAKAEMVGSSTFQRAVVVHSD
RTISVQAINAKPNTADATQLWPVRALGTEYFVFTPSSASSQNLKEFAVVAGAAGASVSIQ
L-GSVTFQGKSYSAGNVLSVTLDPYQVAQVQSTANLSGTV--TASPVAVLSGXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX-XXXXXXXXXXXXXXXQGSH
ELQAGEAEEIQQSPA----LLYEVDIQFRLFGTDT-TKGVTYDPHWVLIPDVT-ACPWYG
VKGIPNCKCVALVVAPTKAGGELTI--DG-QRLGANLTWDVVPGSEFSYAEVDLGTKDSI
HV---AEGATSFVLLTFELNQDVSFRTAAACGRT-LQTQEPSCEGK-QCGPKQLCKVLDG
QARCLADSAAT

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRRYDMMGTCLYSMVELCSD--DQTLPAFSVETKNE
HRGSRSVSYVGLVTVRAYNHAVSLARGEVGFARIDSQRSRLPASLAEGRLRVYQSGTRAM
VELD----FGLVVTYDWDAQLALSLPVHFQGQVCGLCGNYNGDPTDDFLTPDR

ENSGT00760000118896_8_Linker_4_8 (654, 706)

EQ-----
--------APDAVEFASSWKLDDEDYLCEDGCQNNCPSCTPDQAQ

PF08742 // ENSGT00760000118896_8_Domain_8 (706, 781)

HYEDSRLCGMLTQLD
GPFAVCRDALDPQPFLKECVYDLCVASGDRASLCRALNAYAQACLEFGISVGNWRLPASC

ENSGT00760000118896_8_Linker_8_9 (781, 784)

PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYELCGPACPASCNPAAVPSNCSSRPCVEGCVCLPGFVASGGACVATSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF02345 // ENSGT00760000118896_8_Domain_10 (839, 897)

GC
NFEGRPLAPGQEVWADEYCQRRCTCDAAT-QQVRCSDTQGCPAGERCRVQNGLLGC

ENSGT00760000118896_8_Linker_10_11 (897, 904)

YPDS
FGS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1062)

CQASGDPHYVSFDGRRFDFMGTCTYLLAGSCGQA--AGLPAFRVLVENEHRGSQTVS
YTRAVRVEARGVKVAVRREYPGRVLVDGILQYLPFQAADGQVQVFRQGQDAVVRTDFGLT
VTYNWDAHVTAKVPSSYAGALCGLCGNFNGDPADDLALRGG

ENSGT00760000118896_8_Linker_11_13 (1062, 1115)

GQAA-------NALAFGKS
WQEETRP-GCGAAEPGDCPK-------LDNLVAQ

PF08742 // ENSGT00760000118896_8_Domain_13 (1115, 1190)

QLQSKKECGILADPSGPFRECHHTLD
PQGAVRDCVYDRCLLPGQSGPLCDALASYAAACQAAGATVHSWRSEQLC

ENSGT00760000118896_8_Linker_13_14 (1190, 1204)

P----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSYGCPLSCGDLPVPGGCG-FNCKEGCVCDEGFVLNGES
CVPLPSCGCVYEGTYHPPGQTFH--PGSGCNSLCHCEEGGLVSCEPSSCGPHEACQPSGGVLGCVVVGSATCQASGDPHYTTFDGRRFDFMGTC-VYSLARTCGT-QPGLAQFAVLQENVAWGN-GKVSVTRVVTVQVANFTLRLEQKQWK-VTVNGVDKRLPVVLAEGQV---RAS-QHGSDV-VIETD-FGLR-VAYDLAYNVWVTIPGNYYQQLCGLCGNYNGDPKDDFQKPDGS-------------------QAGSSNEFGNSWQEAVPGSPCLP--T--CKPG-ESCDTELECKPELQEKYEQPQFCGLLTSPTGPLAACHKLVDPQGPLKDCVFDLCVGGGNESILCSNVHAYVSACQAAGGHVEPWRTESFC--P-------------------MQCPPNSHYELCADTCSLGCWALSAPPQCPDSCAEGCQCDSGFLNDGQACVPIQECGCYHNGVYYEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------------------------------XXX-XX-XX-XX-XX-X-XX-X-XX-XX-XX-X-XX-XX-XX-XX-XXX-X-XXX-XX-XX-XX-XX-XX-XX-XX-XXX-X-X-XX-X-XX-X-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-XXX-X-XX-X-XX-X-XX-XX-XX-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-X-XX-XX-XXX-X-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-XX-XXX-X-XX-X-XX-X-XX-XX-XX-XXX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XXX-X-XX-XX-XX-XX-X-XX-X-XXX-X-XX-XXX-XX-XX-X-XXX-XX-XX-XXX-XXX-XXX-XX-XX-XX-XX-XX-XX-XXX-XX-XXXXX-X-XX-XX-XX-XXX-X-XX-XX-XX-XX-XX-XX-XX-XX-XXXX-XX-X-XXX-XX-X-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XXX-X-XX-XX-X-XX-XX-XX-XX-XX-XX-XXX-XX-XXX-XX-XXX-XXX-XXXX-XXX-XXX-XX-XXXX-XXXX-XXX-XXX-XXXXX-XX-XX-XX-XX-XXX-XXX-XXXX-XX-XX-XX-XXX-XX-XX-XX-XXX-XX-XXXX-XX-XX-XXX-XX-XXX-XXX------XX-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XXX-XX-XX-X-XX-XX-XX-XX-X-XX-XX-XX-XXX-XX-X-XX-XX-XX-XX-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-X-XX-XXX-X-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XXX-X-XX-XX-X-XX-X-XX-XX-XX-XX-XX-X-XX-XX-X-XX-XX-X-XX-XXX-X-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-X-XX-XXX-X-XX-X-XX-X-XX-X-XX-XX-XX-XX-X-XX-XX-X--X-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XX-XXX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-X-XX-XX-X-XX-XX-XX-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-XX-X-XX-XX-XX-XXX-X-XXX-XXX-XX-XXX-XXX-XX-XXXX-XX-XXX-XX-XX-XXX-XX-XXX-XX-XXX-XX-XX-XX-XX-XX-XX-X-XX-XX-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-X-XX-XX-XX-XX-X-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XX-XX-XX---XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XXX---XX-XX-X-XX-XX-XX-XX-XX-XX-XX-XX-XXXX-XX-XXX-XXXX-XX-XXX-XXX-XXX-XX-XXX-XX-XX-XX-XXX-XX-XX-XX-XXX-XXX-XX-XXX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XX-XXXX-XX-XXX-XX-XX-XX-XX-XX-XX-XXX-XX-XXX-XXX-XX-XXX-XXX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XXX-XX-XXX-XX-XX-XX-XX-X-XX-XX-XX-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-X-XX-XXX-XX-X-XX-XX-X-XX-XX-XX-X-XX-XX-XX-XX-X-XX-XX---XX-XX-XX-XX-X-XX-X-XX-X-XX-XX-X-XX-X-XX-X-XX-X-XX-X-X-XX-X-X-X-X----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------XXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXX---XX----XXXXXXXXX-XXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X----XXXXXXXXXXXXXXXXXXXX------XX--------XXXXXXXX--------XXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXATCWLWGDPHYHSFDGWNFDFHGTCIYVLAST-ICPGSSAQGLTSFTVTTRNDNRGNPSVTYLRLVNVTILPTTISIHKGEIGKVRV-NGVLTALPVSVAGGQLSVTQGVSRAVLATDFGLRVSYDWDWRVEVTLPSSYHGVVCGLCGNMDHNPSNDQAFPNGTLAP-----SIPVWGGSWRVPGWDPLCWDEC---QGSCPTCAEDRLEEYRGPGFCGPLAPGSGGPFAACHAHVAPDSFFKGCVLDVCLGGGAQDILCQALAAYAAACQAAGIVIKDWRTQAGCELSCPENSHYELCGPPCPASCPSPAPPTASAPCGGPCTEGCQCDSGFVLSTDRCVPLDGGCGCWANGTYHEAGSEFWADATCSQRCHCGP----GGGSLVCKPASCGLGEECALLPSGQHGCRPIST----------AECQAWGDPHYITLDRHHFNFQGACEYLLSMPCHRL-PPGVENFTVTVDNEHRGS--QAI-SY-----TRTVTLHIYGHSFTLSARRPRQLQV--------DGTLVALPFQLDS-RLRAHLSGA--DVVVTTAPAISLAFDGDNNVRLRVPAAYAGTLCGLCGNYNQKPNDDLNVV-GNPD--------GWQVGGAEGCG-ECVPGPCPQPCTPEQQEPFGGPDA-------------CGVISA-PDGPLAPCHSHVPP-TQYFQACLLDACQAQGHPGGLCPAVATYVVACQAAGAQLGEWRRPDFCPLQCPAHSHYKLCGDSCPVSCPSLSAPEG-CES--TCREGCFCDAGFVLSGDTCVPVGQCGCLHEGRYYPLGKDFYPGPECERRCECGPGGQVSCQEGAACGPYEECRLQDGVQACRPTGCGRCLASGGVHYITLDGRAY-DLH-------GSCSYILAQVCHPQPGDEDFTIVLENNAAGD-PQRLVVTVAGQVVGLARGP--QVTVDGEAVALPVA--VGHVRVTAEGRNMILQTTKELRLLFDGDAYILISIPSPFRDRLCGLCGNFNGNWNDDFVLPSGAMAPSVDAFGAAWRAPG-S-SQGCGEGCGPQGCPLCSAEETAPYESLEACGRLKDAKGPFSACHAALSPSEYFRQCVYDLCAQKGNSAALCRSLSAYTAACQAAGVAVKP-WRTDSFCPL-------QCPAHSHYSICTRSC----QGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHDGRYLPANSSLLTSDCSERCSCSSSTGQTCQAASCPPGRVCEVQAGVRDCWVSRG-LCSLSVDANLTTFDGARSAVSSP---GIYELSFCCPGLQE-TVPWYRVVADVWPCDSKAAVLGHVHIFFQDGLVTVTRKKGV-WVN-GVQV----DLPAEVLTSVSVSRNPDGSVLVQQKAGVRVQLGTDGQLAVVVSDDHAGMLCGACGNFDTDQTNDGHDSQ

PF02822 // ENSGT00760000118896_8_Domain_15 (1244, 1269)

CKEGCVCDEGFVLNGESCVPLPSCG

ENSGT00760000118896_8_Linker_15_19 (1269, 1332)

CVYEGTYHPPGQTFH--PGSGCNSLCHCEEGGLVSCEPSSCGPHEACQPSGG
VLGCVVVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1498)

CQASGDPHYTTFDGRRFDFMGTC-VYSLARTCGT-QPGLAQFAVLQENV
AWGN-GKVSVTRVVTVQVANFTLRLEQKQWK-VTVNGVDKRLPVVLAEGQV---RAS-QH
GSDV-VIETD-FGLR-VAYDLAYNVWVTIPGNYYQQLCGLCGNYNGDPKDDFQKPDG

ENSGT00760000118896_8_Linker_19_22 (1498, 1566)

S--
-----------------QAGSSNEFGNSWQEAVPGSPCLP--T--CKPG-ESCDTELECK
PELQE

PF08742 // ENSGT00760000118896_8_Domain_22 (1566, 1643)

KYEQPQFCGLLTSPTGPLAACHKLVDPQGPLKDCVFDLCVGGGNESILCSNVHAY
VSACQAAGGHVEPWRTESFC--

ENSGT00760000118896_8_Linker_22_24 (1643, 1665)

P-------------------MQ

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPPNSHYELCADTCSL
GCWALSAPPQCPDSCAEGCQCDSGFLNDGQACVPIQECGCYHNGVYYEXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------
------------------------------XXX-XX-XX-XX-XX-X-XX-X-XX-XX-X
X-X-XX-XX-XX-XX-XXX-X-XXX-XX-XX-XX-XX-XX-XX-XX-XXX-X-X-XX-X-
XX-X-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-
XX-XXX-X-XX-X-XX-X-XX-XX-XX-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-X-X
X-X-XX-XX-XXX-X-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-XX-XXX-X-XX-X-X
X-X-XX-XX-XX-XXX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XXX
-X-XX-XX-XX-XX-X-XX-X-XXX-X-XX-XXX-XX-XX-X-XXX-XX-XX-XXX-XXX
-XXX-XX-XX-XX-XX-XX-XX-XXX-XX-XXXXX-X-XX-XX-XX-XXX-X-XX-XX-X
X-XX-XX-XX-XX-XX-XXXX-XX-X-XXX-XX-X-XX-XX-XX-XX-X-XX-XX-XX-X
X-XX-XX-XXX-X-XX-XX-X-XX-XX-XX-XX-XX-XX-XXX-XX-XXX-XX-XXX-XX
X-XXXX-XXX-XXX-XX-XXXX-XXXX-XXX-XXX-XXXXX-XX-XX-XX-XX-XXX-XX
X-XXXX-XX-XX-XX-XXX-XX-XX-XX-XXX-XX-XXXX-XX-XX-XXX-XX-XXX-XX
X------XX-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XXX-XX-XX-X-XX
-XX-XX-XX-X-XX-XX-XX-XXX-XX-X-XX-XX-XX-XX-XXX-XX-XX-XX-XX-XX
-XX-XX-XX-X-XX-XX-XX-X-XX-XXX-X-XX-XX-XX-XX-XX-X-XX-XX-XX-XX
-XX-XX-XXX-X-XX-XX-X-XX-X-XX-XX-XX-XX-XX-X-XX-XX-X-XX-XX-X-X
X-XXX-X-X-XX-XX-X-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-X-XX-XXX-X
-XX-X-XX-X-XX-X-XX-XX-XX-XX-X-XX-XX-X--X-XX-XX-XX-X-XX-XX-XX
-XX-XX-XX-XX-XXX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-X-XX-XX-X-X
X-XX-XX-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-XX-X-XX-XX-XX-XXX-X-XX
X-XXX-XX-XXX-XXX-XX-XXXX-XX-XXX-XX-XX-XXX-XX-XXX-XX-XXX-XX-X
X-XX-XX-XX-XX-X-XX-XX-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX
-XX-X-XX-XX-XX-XX-X-XXX-XX-XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-X
X-XX-XX-XX-XX-XX---XX-XX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-X-XX-X
X-XX-XX-XX-XX-XXX---XX-XX-X-XX-XX-XX-XX-XX-XX-XX-XX-XXXX-XX-
XXX-XXXX-XX-XXX-XXX-XXX-XX-XXX-XX-XX-XX-XXX-XX-XX-XX-XXX-XXX
-XX-XXX-XX-XX-XX-XX-XX-X-XX-XX-XX-XX-XX-XX-XX-XXXX-XX-XXX-XX
-XX-XX-XX-XX-XX-XXX-XX-XXX-XXX-XX-XXX-XXX-XX-XX-XX-XX-XX-X-X
X-XX-XX-XX-XX-XX-XXX-XX-XXX-XX-XX-XX-XX-X-XX-XX-XX-X-XX-XX-X
-XX-X-XX-XX-X-XX-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-XX-X-XX-
XX-X-XX-X-XX-XXX-XX-X-XX-XX-X-XX-XX-XX-X-XX-XX-XX-XX-X-XX-XX
---XX-XX-XX-XX-X-XX-X-XX-X-XX-XX-X-XX-X-XX-X-XX-X-XX-X-X-XX-
X-X-X-X----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------XXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXX---XX--
--XXXXXXXXX-XXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X----XXXXXXXXXXXXXXXX
XXXX------XX--------XXXXXXXX--------XXXXXXXXXX----XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAT

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYHSFDGWNFDFHGTCIYVLAST-ICPGSSAQGLTSFTVTTRNDNRGNPSVTYLRLV
NVTILPTTISIHKGEIGKVRV-NGVLTALPVSVAGGQLSVTQGVSRAVLATDFGLRVSYD
WDWRVEVTLPSSYHGVVCGLCGNMDHNPSNDQAFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5605)

TLAP-----SIPVWGGSWRVPGW
DPLCWDEC---QGSCPTCAEDRLE

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

EYRGPGFCGPLAPGSGGPFAACHAHVAPDSFFKGCV
LDVCLGGGAQDILCQALAAYAAACQAAGIVIKDWRTQAGC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

ELS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPENSHYELCGPPCPAS
CPSPAPPTASAPCGGPCTEGCQCDSGFVLSTDRCVPLDGG

ENSGT00760000118896_8_Linker_75_76 (5741, 5742)

C

PF02345 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADA
TCSQRCHCGP----GGGSLVCKPASCGLGEECALLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

RPIST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 6008)

C
QAWGDPHYITLDRHHFNFQGACEYLLSMPCHRL-PPGVENFTVTVDNEHRGS--QAI-SY
-----TRTVTLHIYGHSFTLSARRPRQLQV--------DGTLVALPFQLDS-RLRAHLSG
A--DVVVTTAPAISLAFDGDNNVRLRVPAAYAGTLCGLCGNYNQKPNDDLNVV-GNPD--
------G

ENSGT00760000118896_8_Linker_77_82 (6008, 6036)

WQVGGAEGCG-ECVPGPCPQPCTPEQQE

PF08742 // ENSGT00760000118896_8_Domain_82 (6036, 6126)

PFGGPDA-------------CGVIS
A-PDGPLAPCHSHVPP-TQYFQACLLDACQAQGHPGGLCPAVATYVVACQAAGAQLGEWR
RPDFC

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

PLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYKLCGDSCPVSCPSLSAPEG-CES--TCREGCFCDAGFVLSGDTCV
PVGQCGCLHEGRYYPLGKDFYPGPECERRCECGPGGQVSCQEGAACGPYEECRLQDGVQA
CRPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6409)

CLASGGVHYITLDGRAY-DLH-------GSCSYILAQVCHPQPGDEDFTIVL
ENNAAGD-PQRLVVTVAGQVVGLARGP--QVTVDGEAVALPVA--VGHVRVTAEGRNMIL
QTTKELRLLFDGDAYILISIPSPFRDRLCGLCGNFNGNWNDDFVLPSG

ENSGT00760000118896_8_Linker_85_88 (6409, 6451)

AMAPSVDAFGAA
WRAPG-S-SQGCGEGCGPQGCPLCSAEETA

PF08742 // ENSGT00760000118896_8_Domain_88 (6451, 6527)

PYESLEACGRLKDAKGPFSACHAALSPSEY
FRQCVYDLCAQKGNSAALCRSLSAYTAACQAAGVAVKP-WRTDSFC

ENSGT00760000118896_8_Linker_88_89 (6527, 6537)

PL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTRSC----QGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF02345 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTHDG
RYLPANSSLLTSDCSERCSCSSSTGQTCQAASCPPGRVCEVQAGVRDC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

WVSRG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6820)

CSLSV
DANLTTFDGARSAVSSP---GIYELSFCCPGLQE-TVPWYRVVADVWPCDSKAAVLGHVH
IFFQDGLVTVTRKKGV-WVN-GVQV----DLPAEVLTSVSVSRNPDGSVLVQQKAGVRVQ
LGTDGQLAVVVSDDHAGMLCGACGNFDTDQTNDGHDSQKETTLENWRAQDFSPCLD----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSPWSLWAL----------W-------
--------------------------AGAALLWARLSPGEASCQGI-QCTSGQRCQMVSG
KARCVAESIAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELNGD--DETLPAFSVEAKNE
HRGSRQVSYVGLVTVHAYSHSVTLVRGETGLARIDSQRSRLPASLSEGRLRVYQSGTRGV
IELD----FGLVVTYDWDGQLTLSLPKRFQNQVSGLCGNYNGDPADDFLTP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DREQ-----
--------APDALEFANSWKLDDGDYLCDDGCHNTCPSCTAGQTQHYKGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLALST
GPFSACHELLDPKPFLEDCVFDLCVTGGERLSLCRSLSAYAQACVELGVSIGNWRSPTN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSCYDPCSPACPASCNSEALPTNCSGRPCVEGCVCLPGFVASGSDCVPVSS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
VYQGRPLAPGQEVFADDLCRQRCTCDGAS-QKVICRDTPGCPSGERCRVLDGLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1059)

CQASGDPHYVTFDGRRFDFMGTCTYLLVGSCGQD--ATLPEFKVLVENEHRGSQTVS
YTRAVRVVAHGVEVAVRREYPGRVMVDGILQYPPFQAAGGKIQVFRQGNDAVIRTNFGLT
VTFNWNAHVTAKVPSSYSEAVCGLCGNFNGNPADDLAL

ENSGT00760000118896_8_Linker_11_13 (1059, 1121)

KGGGQAN-------SALDFGNS
WQEEIIP-GCGATDAGDCPQ-------LDSLVAQQQQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPEGPFRECHKLLN
PQGALRDCVYDLCLLPGQSKPLCDALAAYAAACQAAGGTVHPWRSEKL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPNS---------HYELCSYGCPLTCGDLPVPQGCG-SECRESCVCDEGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGSYYPPGETFY--PGPGCDSLCHCQEGGLVSCEPSSCGPHEACQPSNG
ALG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVPVGTTT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYISFDGRRFDFMGTC-VYVLAQTCGT-RPGLHQFTVLQENA
PWGN-GHVSVTKAITVLVANYTLRLEQNQWK-VKVNGVDMKLPVVLDGGKI---RVS-QH
GSDA-VVETD-FGLR-VTYDLVYHVRVTIPGNYYQQMCGLCGDYDGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAANPSDFGNSWEEAVPDSPCAPV-P--PCT-GDDCPT--ECS
PELEDKYHGLQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLLAS------------------------------------------
------------------------------------------------------------
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-----------------------------------------------PTGPLAACHKLLD
PQGPLKD---------------CVFDLCLGGGNQSILC-------------------DNI
HAYVSACQAAGGK--------------------VEPWRTETF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPMV-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLGCWAFSAPQ--QCPE---
---------GCAEGCECDSGFLYNGK------ACVPI----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGAYYEPEESVL
IE----------------------NCQQQCVCHAGEG----------------------M
VCKDHSCKPGQVCEPSGGV------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDPCHGVTCRPQETCK-----------VQG
GQGVCVPNYNST

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------NFDFQG-TCNYLLAGT-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VCPGVSAEGLTPFTVTTKNENRGNPAVSYVRLV
TVSALNTNISIHKNEIGKVRV-NGVLQTLPVYLAGGRISVVHGGSKAVLQTDFGLQVTYD
WNWRVEVTLPSSYHGAVCGLCGNMDKNPQNDKVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TVAP-----SIPTWGGSWQIPGW
DPLCWHEC---QGSCPMCSEDQMEKYEGPGYCGPLAPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

AGGPFASCHAHVPPESFFKGCV
LDVCLGGGLKDILCQALAAYAAACQAAGIQIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPPCPAS
CPPPARHTAPAACDGPCVEGCQCNQGFVLSAEQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYHEAGTEFWTDA
TCSKKCHCGP----GGDSLVCKSASCGLGEECALLPSGQLGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPTST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYITLDGHRFDFQGTCEYLLSAPCQEP-PTGTEYFNVTVTNEHRGS--QAV-SY
-----TRSVSLNIYGLSLTLSAQWPRRLQV--------NGEFVALPFHLDQ-RLSVYLSG
A--DVVVNTAAGLSLAFDGNSFVRLRVPAAYAGALCGLCGNYNKNPKDDLKAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPE--
------GWKVGGAPGCD-QCEPEPCPKPCTPEQQEPFRGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIS
A-PEGPLAPCHSLVPP-TQYFEACLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYELCGDSCPVSCPSLEAPKG-CET--TCREGCVCDSGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLYNERYYLLGATFYPGPECERLCECGPNGKVTCQEGGDCEPYEECRIENGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGH

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYVTLDGRVY-DLH-------GSCSYILASVCHPKPGDEEFSIVL
EKNSAGE-PQRVVVTVEGQVVVLAQGP--QVTMDGEAVALPVT--KGRVSVTAEGRNMIL
QTEKGMKVLFDGDAHILMSIPSPFRGRLCGLCGNFNGNWSDDFVLRD

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GAVAPSVEAFGAA
WRAPDS--SPGCSEGCGSQGCPVCLAEETAAYEKNDA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKIRDPKGPFADCHRVLSPLEY
FRQCVYDQCAHKGNKTYLCRSLAAYTAACQVAGATVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTGSC----QGSCAALSGLTQCTTRCFEGCECDDHFLLSQGVCIPAHD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTYNG
QYMPVNTSLMTSDCQELCCCSSRTGLTCHAAGCPSGQVCELQGGVRSC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QPARG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6820)

CSISV
GGNFTTFDGAHSVISSP---GVYELSSRCPGLQE-TVPWYRVVADVQSCHGNDKVVDKFH
IFFQDGIVTVTQNKGV-WVN-GLRV----DLPAQVLTSVSVRRMPDGSVLVHQKAGVQVW
LGTDGQLNVMVGDDHAAMVCGACGNFDGDQTNDMLDSEGKKPMEKWEAQDFSPCSN----
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MCLC--
--HLSLSAAYMAFVLRSASRDPVSV--PP-AGMGSLWSWWSL----------W-------
--------------------------AGTILLWATLPTVKPSCQGV-QCAAGQHCQVVGS
QARCVAQSTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCTYTLAELCGE--DETLPAFSVEAKNE
HRGSRLVSYVGLVTVHAYSHSVTLARGEVGFVRIDSQRSRLPTSLSNNRLRVYQSGTRAV
VELD----FGLVVTYDWDCQLTLSLPERFQNQVCGLCGNYNGNPADDFFTP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DLEQ-----
--------VEDPDEFASHWKLDDGDYLCDDGCQNKCPACTPGQAQHYEGSPL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLPN
GPFAACHESLDPQPFLKDCVYDLCVTGGERLSLCRGLSAYVQACMELGISIGDWRSLAN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PMT

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYERCAPACPATCNSEAAPSNCSARLCVEGCVCLSGFVASGGACVPASSCGC
VHEGLTLAPGQQLWGDDLCRSRCTCDGAT-QKVTCRDTQGCPQGERCRVENGLLGCYPDN
FGT

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYVSFDGRRFDFMGTCTYLLVGTCGQDRHEALSTFRVLVENEHRGSQTVS
YTRAVRVEVHGVQLALRREYPGQVLVDGILHYLPVQAADGQVQVFRQGNEGVIRTNFGLT
VTYNWDALVTAKVPSSYAEALCGLCGNFNGNAADDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1122)

GGGQAA-------NALDFGNS
WQEEATL-GCGATPPGDCPA-------LDSMVAEELKNKSG

PF08742 // ENSGT00760000118896_8_Domain_13 (1122, 1187)

CGIIADPEGPFRECHNTLD
PQGAVRDCVYDLCLLPGQSRPLCDALTSYAAACQAAGATVHPWRD-

ENSGT00760000118896_8_Linker_13_14 (1187, 1204)

QLCP----------
-PS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCSHGCPLSCGDLPMSGGCG-SECHEGCVCDDGFVLSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCLYQGAYHPPGQTFH--PGPGCDSLCHCEEGGLVSCEPSSCGPHEECQPSNG
VLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGRRYDFMGTC-VYVLAQTCGT-RPGLHNFTVLQENA
PWGN-GHVSATRVVTVIVGNYTLRLEQSQWK-VRVNGVDMKMPVELAGGQI---RVF-QH
GSDA-VIETD-FGLR-VAYDLTYYVRVTVPGNYYQQMCGLCGDYNGDPKDDFQKPN

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAANPNEFGNSWEEQVPDSPCVHQPG--CEPGEGDCG---KCS
SELEEKYKKNEF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGILTN------------------------------------------
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------------------------------------------------------------
-----------------------------------------------LEGPLAACHKLLD
PQAPLQD---------------CIFDLCLGGGNLSILC-------------------DNI
HAYVSNCQAAGGH--------------------VDPWRTDSF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPIT-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PNNSHYEVCADV------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLSCAALRVPL--QCPD---
---------KCAEGCQCDSGFLYNGH------ACVPI----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHDGTYYEPQETVL
ID----------------------SCQQQCVCHANGS----------------------M
DCQNHSCKPGEVCKPLDGV------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVKIDPCDGVKCRPQETCK-----------DQG
GQGVCVPNYHVT

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------AFDFQG-TCDYVLAAV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPGVSAEGLTPFTVTTKNENRGSPAVSYVKRV
TVSALGTNISIHKNEFGRVRV-NDVLTALPVSAAGGRILVTQGPGKAILVAAFGLQVTYN
WDWQVEVTLPSSYHSAVCGLCGNMDQDPSNDRVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TLAP-----SIPTWGGSWRVPGL
DPFCWDEC---QGSCPTCSEDQQEKYKGPSFCGPLAPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

SSGPFAACHAKVPPESFFTGCL
LDVCLGGGAQDILCQALAAYAAACQAAEVVIGEWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5737)

CPANSHYELCGPPCPAS
CPSPSSSSTPAVCEGPCTEGCQCDDGFVLSAGRCVS

ENSGT00760000118896_8_Linker_75_76 (5737, 5742)

LNGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANDIYYEAGSEFWADG
TCSQLCRCES----GNGSLVCTPASCGSGQECALLSSGQYGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYTTLDGHHFDFQGTCEYLLSAPCDTP-PKGTENFTVTVANEHRGS--QAV-SY
-----TRSVTLYVYGHALTLSASQPRQIQV--------DGKIVNLPFQLDS-SLHAYLSG
N--DVVVTTDFGLSLSFDGDSFVRLRVPAAYAGALCGLCGNYNKDPSDDLAAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPS--
------GWQVGGAPDCE-KCVPEPCPEPCTEEEKKAFAGTDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-PDGALAPCHTLVPP-EKYFQACLLDACQAQGHPSGLCPAIATYVAACQAAGAQLGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPYE

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CSDNSHYELCSDSCPISCPSLSAPEG-CES--TCREGCVCNSGFVLSGGTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6241)

GCLYNDHYYLVNETFYPGPECERYCKCGPGGQVSCQEGKACRPYEECRVEDGVQA

ENSGT00760000118896_8_Linker_84_85 (6241, 6249)

CYPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CMVSGGIHYISLDGRVY-DLH-------GSCSYVLAKVCQPDPEDDDFSIVL
EKDEAGR-PHRVLVTVADKVVSLAGGP--KVTVNGENVNLPVA--LDHVHVAAEGRNMIL
QTTEGLRVLFDGDAHILMSIPSTFRGRTCGLCGNFNGNWSDDFVLPD

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

NKVASSVEAFGTA
WRAPDS--YPGCSEGCGSQGCPVCLAQETAVYESNEV

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKLLDTNGPFSACHSVVNPSEY
FRQCVYDQCAQKGDKAFLCRSLAAYTADCQAAGATVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAN
SHYSICMHSC----QTSCAALSGLKGCTARCFEGCECDDRFLLSHGVCVPIQE

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTHNG
RYLPVNTSLLMSDCSECCSCSSRTGLTCQATSCPADQVCDLQEGSWVC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

HVAHG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6818)

CSISV
GANLTTFDGVHSAIGSP---GIYELSSHCSGLEE-SIPWYRVLADVQSCKNNAKAVDKVH
IFFKDGIVTVTRSKGV-WVN-GQQV----DLPAEVLTSVSISRASDGSVVVSQKAGVRVR
LGSDGHLEVTVDDELAGKLCGACGNFDGKQDNDL---TGEEAVEKWEAPDFSTCDN----
-

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----MGGG

PF08742 // ENSGT00760000118896_8_Domain_74 (5649, 5680)

AHDILCQALASYAAACQAAGIVIEDWRAQVG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CAIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYEFCGPPCPAS
CPSPAPPTTPAVCQGPCVEGCQCNAGFVLSADRCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

SNGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGTEFWADG
TCSQRCRCGP----GGGSLVCTPASCGLGEACALLPSGQYGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5990)

C
QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHAL-PTGAENFTVTVANEHRGS--QAV-SY
-----TRSVTLHIYNHSLTLSARWPRQLQV--------DGEFVALPFQLDS-LLQAHLSG
A--DVVVTATSGLSLAFDGNSFVRLRVPAAYAGSLCGLCGNYNQNPADD

ENSGT00760000118896_8_Linker_77_82 (5990, 6056)

LKAVGGNPA--
------GWQVGGAPGCG-ECVSGPCPQPCTPEQQEAFGGTDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-TDGPLAPCHGLVPP-AQYFQGCLLDACQAQGHPGGLCPAVAAYVAACQAAGAQLDEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGDSCPVSCPSLSAPEG-CES--ACREGCVCDAGFVLSGDSCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYPLGQTFYPGPECERRCECGPRGHVTCQEGSACGPHEECRLEDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HATGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLASGGIHYITLDGRVY-DLH-------GSCSYILAQVCRPKPGDEDFSIVL
EKNAAGD-PQRLLVTVAGQVVSLARGL--QVTVDGEAVALPVA--VGRVRVTAEGRNVVL
QTTKGLRLLFDGDAHILMSIPSPFHGRLCGLCGNFNGNWSDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GAAASSVETFGAA
WRAPG-S-SQGCGEGCGPQGCPVCLAEETAPYEGNEA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLRDPQGPFATCQAVLSPSEY
FRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------Q

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTRTC----QGSCAALSGLTGCTTRCFEGCECDDRYLLSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHNG
RYLPVNSSLLTSDCSERCSCSPSSGLTCQAAGCPPGHICEVQAEARD

ENSGT00760000118896_8_Linker_90_91 (6648, 6659)

CWAPRG-LCFL

PF00094 // ENSGT00760000118896_8_Domain_91 (6659, 6814)

SV
GANLTTFDGAHGAITSS---GVYELSSRCPGLEK-TIPWYRVVADVQTCHGKAEAVGQVH
IFFQDGMVTVTPNKGV-WVN-GLRV----DLPAEKLASVSVSRTPDGSLLVRQEAGVQVW
LGADGKLAVMVSNDHAGKLCGACGNFDGDQTNDGHNSQQKPAVEKWRAQDFSPCYD----
-

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---

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSYGCPLSCGDLPVPGGCG-SECHEGCVCDEGFALSGES
CLPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYHPPGQTFY--PGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG
SLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSST

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGRRFDFMGTC-VYVLAQTCGT-RPGLHRFAVLQENV
AWGN-GRVSVTRVITVQVANFTLRLEQRQWK-VTVNGVDMKLPVVLANGQI---RAS-QH
GSDV-VIETD-FGLR-VAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QAGNANEFGNSWEEVVPDSPCLPPTP--CPPGSEGCNSSGECP
PELEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLSSPTGPLSSCHKLVDPQGPLEDCVFDLCLGGGNLSILCSNIHAY
VSACQAAGGHVEPWRNETF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------ME

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPLNSHYELCADTCSL
GCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQ

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1772)

GCYHNGVYYEPEQTVLIDNCQQ
QCTCHAGKGVVCQEHSCKPGQVCQPSGGILSCVTK--DPCHGVTCRPQETCKEQG-----
--------GQG------VCL--PN-YE----ATC---

PF00094 // ENSGT00760000118896_8_Domain_31 (1838, 2340)

-WLWGDPHYHSFD----GRKFDF
------Q----GTCN--YVL---AT----TGCP--GV-----STQGLTPFTITT-----K
NE-----NRG--NPAVS----YV--RVVTV------------------------------
--------------------------------A--A-LG-TN-IS-I----------H-K
D-E--------I---------------------G-KV-R---------------------
----------------------------------------------------VN-GV-L-
TA-LPV-S-VA-D-RR-I-SV-TQ-GA-S-KA-LL-V-----------------------
-----------AD-F-G-LQ-VS-Y-DW-N-WR-V---------------D-V-TL-P-S
S-Y-HG-AV-CG-LCG-NM-DR-NP-N-ND-QV-FP-NG--------------------

ENSGT00760000118896_8_Linker_31_32 (2340, 2436)

T
-L-AP-SI-PI-WG-G-SW-R-A----------P-GW-DP-L-CWD-EC-RG-SCP-TCP
-EDR-LE-QY-EG-PG-FC-GP-LAP------GTG

PF08742 // ENSGT00760000118896_8_Domain_32 (2436, 2555)

-G-PF-TT-CH-AHV-P-PE-SF-F
K-GC-VL-DD-L-------------------------------A-SY-V-AR--------
---------CQ-A-AG-IV-I-ED-WR-AQ-VG-CE-IT-LPR-K---------------
--HCRS-PAP-LTT-SR-YARA-PCVE-GCQ-CDA-------VA-DR-CV-PS-TTA-GR
C-WANG-TY-TR-RA-VSF-GL-MA-PA-SAV-SL-RA-----------W-GG-------
--------------------------------------------------SW-SA-H-LP
-------AV-G-WV-KC-VA-PAI-AA-H-GC-QP-VS-TA-ECQ-AW-GD-PI-TS-LL
------------------------D-WHR-F-DF-QG-TC-EY-LL-T-MS-TR-GS-QA
-VA-TP-AWG--------------------------------------------------
------------------QD-S-NP-CL-L-RS-PL-P-PC-PQ

PF00094 // ENSGT00760000118896_8_Domain_36 (2985, 3094)

-V-DG-V-FV-A-L-P
-FQ-L-DS-L-LH-A-HL-SG-TD-VV-V-TT-TS-GL-S-LA-FD-GD-S-FV-RL-RV
-PA-AY-AG-SL-CGL-CG-NY-NQ-DP-AD-D

ENSGT00760000118896_8_Linker_36_37 (3094, 3233)

L--------------------------
--------------------------------------------------K-AVG-G-KP
A-GWQ-VG-GAQ-GCG-EC-V-SK-PC-PSP-CT-PE-QQE-SF-GGP-DA-

PF08742 // ENSGT00760000118896_8_Domain_37 (3233, 3409)

CGV-IS-A
T-DG-PL-A--------------PC-HG-LV-PP-AQ-YF-QG-CL-L------------
----------------------D-AC-QV-QG-HP-GG----------------------
-----LC-PA-VA-AY---VA-AC-QA-AG-AQ-LG-EW-R-RP-DF-CR-E--------
---------------YC---SM-HG-P-HS-RV---------------------------
--S-PCPS------Q-DCR-TAA-PS-S--------------------------------
-----------SV-RL-R-------------------------------------VH-LP
-SR-AR-YL-LS-GN-TLG-GE-VSC-EPS-SC-GPH-ETC-RP-SG-G-----------
---------------S-LGC-VA-VGS-TT-

PF00094 // ENSGT00760000118896_8_Domain_27 (3692, 4032)

CQ-AS-GD-P-------------------
------------H-YT-TF-DG-R-RF-D-------------------------------
-----------------------------------------------FM-GT-C-VY-VL
---AQ-TC-GT-RP-G-LH-R-FA-V-LQ-EN-V-AW-----------G-NG-R-V-SV-
T-R-V-I----------TVQVANFTLRLE---------------QRQWKVTVNGVDMKLP
VVLANGQIRASQHGSDVVIET-----DFGLRVAYDLLYYVRVTVPGNYYQQMCGLCGNYN
GNPKDDFQKPN

ENSGT00760000118896_8_Linker_27_55 (4032, 4107)

GSQAGNANE------FGNSWEEVVPDSPCLPPPTCPPGS----------
--EGCNSSG--ECPPELEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_55 (4107, 4243)

CGL---------------LSSPRGPLASCHKLVD
PQGPLED---------------CIFDLCLGGGNLSILC-------------------SNI
HAYVSACQAAGGH--------------------VEPWRNETF

ENSGT00760000118896_8_Linker_55_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4704)

C
PLNSHYELCADT------------------------------------------------
------------------------------------------------------------
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---------------------------------------CSLGCSALSAPL--QCPDGCA
------------EGCQCDSGFLYNG-----------------------------------
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PF00094 // ENSGT00760000118896_8_Domain_73 (5482, 5558)

VNGTLAHLPLHLAGGLVHVYFSGSGAVLQTSTGLLVSYD
WRHHVSVMVPETYAGALCGLGGDFNGDPLDDFRAPNG

ENSGT00760000118896_8_Linker_73_74 (5558, 5605)

SLLH-----DAEAFVFSWKDPAS
PAGCWVT-----GPAPLCPHDTGG

PF08742 // ENSGT00760000118896_8_Domain_74 (5605, 5681)

RYQSLAFCGLLA-TQNGPFQACDEPAEAQVHMENCV
HDLCATGGSRQILCEVLGSYAQQCQRHGLPVQPWRHLVDC

ENSGT00760000118896_8_Linker_74_75 (5681, 5684)

ELA

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5741)

CPPHSHYELCGSSCPSS
CAEPAL---PDSCPTPCQEGCQCDPGFMLSGTDCVPPT-QCGCSLEGRYHLPGEIFWAGE
RCERLCYCEA----STGMVRCSPYSCGPGQRCGVL-RGVFGCHALSP----------GT

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5996)

C
QVAGHAHIIAFDGRPVALPSTCALVLAESCGAPGLLPVFKVEESLLSASRPDASVFY---
---------------------------------------------SD---C-P----LS-
GSIHTLSFVGTRLQVHFSGRHTLLLRVGPEYRGRLCGLCGNFNDDPDDDKVLPSGAPARS
DAEFGNAWQTQDSGPRVA--M--------QGHRGLXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXLA

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6187)

CPPHSHYELCGSSCPSSCAEPALPDS-CPT--PCQEGCQCDPGFMLSGTDCV
PPTQAACSLE--------------------------------------------------
------------------------------------------------------------
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-

------------------------------------------------------------
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-------MGSLWSWWTLWAGAALLWAGR---------SSADPCQGV-QCPVGQHCRAQGR
KTSCVRDPTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGRPYDMMGTCSYTMAELCGQ--DDTLPAFSVNAKNE
HRNSRLVSYVGYVTVLAYSHSVSLARGEVGFTRIDNQRSRLPASLSEGRLRVYQSGTKAV
VELD----FGLVVTYDWDAQLTISLPERFQNQVCGLCGNYNNNPGDDLLTPDG

ENSGT00760000118896_8_Linker_4_8 (654, 713)

TL-----
--------VSDIVGFASSWKLDDGDALCDDGCQNNCPSCTPDQTQQYGDNRV

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGVLTVPE
GPFAACHESLDPHLFLENCIYDLCATGGDRISLCRALGAYAQACTELGISVGDWRSRVN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
SMS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSTYQPCAPPCPATCNSEASPANCSGRSCVEGCVCREGFVMSGGACVPASS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TYEGQLLAPGQAIWADDQCSQRCTCDGAT-HTVSCQSVKGCPAGELCQVQNDLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPTS
FGS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYVSFDGRRFDFMGTCMYLLVGSCGQD--PALPTFRVLVENEHRGSKTVS
YTRAVRVEAHGVEVAVRRENPSQVLLNGILQHLPFQAADGRVQVFRQGRDAVVRTDFGLT
VTYNWDALVTVKVPSSYAKALCGLCGNFNGDPSDDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

GGGQAA-------NALDFGNS
WQEEPSPDTCGAGQPGNCPK-------LDSLVTEQVQSKK

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADSSGPFRECHGKVD
PQGAVRDCAYDLCLLPGQPELLCEALAAYAEACQAAGATVQPWRTEEF

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CQFLMPLAPLPA
ALT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSRGCPLSCGDLPVPGGCG-TECYEGCVCDDGFALSGGS
CVALAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYYQPGQSFY--PGPGCETFCHCQEGGLLSCEPSSCGPQEACQPSNG
ILG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSVT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTSFDGRRFDFMGTC-VYVLAQTCKT-QPGLPHFTVLQENA
PWGN-GKVSSTKVITVLVANHTLRLEQMQST-VKVDGVDQKLPVELAEGAV---RAF-QH
GSDV-VVETD-FGLR-VAYDLMYYVRVTVPGNYYKQMCGLCGDYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QVADPNDFGNSWEEAVPDSPCAPPPP--CE--------DCHCS
PELEEKYKKEQF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLASTTGPLANCHKLVPPEGPLEECVFDLCLGEGNLTILCSNIHAY
VSACQAAGGHVEPWRTESF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

C--P-------------------ME

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPPHSHYKPCANTCSL
SCSALSAPLKCPEVCAEGCECDPDYLYNGQACVPIQE

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1769)

GCYYKGIYYELEQKVLIDDCQQ
ECVCHANGIMACQNHTCKPEEVCKPHEGVL------------------------------
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--------------------------KPCHNVICKPQEICEVQNGVGICVPISEVM

PF00094 // ENSGT00760000118896_8_Domain_70 (5397, 5558)

CWLW
GDPHYHSFDGWAFDFQGTCNYVLATT-DCPGVSSQNLTPFTVTTKNENRGNPSVSYVKLV
TVNTLNTNISIHKNEIGKVRV-NGVRTTLPVSVAGGRISVTHGASKAVLVTDFGLQVTYD
WNWKVEVKLPSSYRKAVCGLCGNMDKNASNDQVFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5612)

TVAP-----SIPTWGGSWRVPDW
DPFCWDEC---KGSCPTCPEERLEEYKGPNF

PF08742 // ENSGT00760000118896_8_Domain_74 (5612, 5680)

CGPLAPNTNGPFTSCHAHLPPENYFKGCV
LDVCLGGGTQDILCQALAAYAAACQAAGITIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIS

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYELCGPPCPAS
CPPPEPTTKPAVCEGPCAEGCQCNEGFVLSGHRCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYYEAGSEFWADA
SCSQRCHCGP----QGGSLSCTPGSCGLGEQCTLLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5990)

C
QAWGDPHYTTLDGHRFDFQGTCEYLLSEPCPEP-PKGTENFTVTVVNEHRGS--QAV-SY
-----TRSVTLHVYGHSLTLSARWPRKLQV--------DGELVALPFQKDP-LLHAHLSG
A--DVVVTTAFGLSLTFDGNSFVRLRVPAAYAGALCGLCGNYNKNPADD

ENSGT00760000118896_8_Linker_77_82 (5990, 6056)

LDAVGGKPE--
------GWQVGGEPGCG-ECVPGPCPAPCTPAEQESFGGPNA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGMIS
A-PDGPLAPCHKLVPP-DQFFKACLLDACQTQGHQGGLCPALAAYVAACQAAGAILEEWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPANSHYELCGDSCPVSCPSFTAPEG-CES--TCREGCVCDADFVLSGDTCV
PVSQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6241)

GCLHDGRYYPLGATFYPGPECGRRCECGPHGQVSCLDGEACGPYEECRREDGVQA

ENSGT00760000118896_8_Linker_84_85 (6241, 6249)

CYPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CMANGGIHYVTFDGRVY-DLH-------GTCSYVLAEVCLPKSGDEKFSIIL
EKNTSSEQSHRLRVTVDEQVVSLDQGP--TVTVNGEAVALPVS--VGPVRVTSEGRHLIL
QTTKGLRILYDGDFHILISVPSSFHGRVCGLCGNFNGNWSDDFALPT

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GKVTDSVEVFGAS
WKDMDSS-QEGCFEGCGPQGCPVCLAEETKPYEGNKV

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGMLQDPQGPFATCHKVLKPSEY
FRQCVYDLCAHKGDEAFLCQHLAAYTADCQAAGSSVKP-WRSDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CSL-------K

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTHHC----PGSCAALSGLTGCTSRCFEGCECDDRFLLSQGVCIPAQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6649)

GCTYQG
RYLPVNSSLLNSDCSERCSCSSSKGLTCEAASCPAGHVCGIREGSRKC

ENSGT00760000118896_8_Linker_90_91 (6649, 6656)

QAAQG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6822)

CTLSL
GAQITTFDGANSTFSSP---GVYEISSRCPTLRP-TIPWYRVVANVQPCHEKPETVSQFH
IFFQEGIVTVTPGKGV-WVN-GLPV----DLPAEVFSSVSVRQTPDGSTLVTQKGGVQIQ
LETNGKLAVMVGDEHSGKLCGACGNFDGVHTNDVP---TETGMEKWKAKDFSQCYD----
-

------------------------------------------------------------
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--------------------------------MGSLWSWWTL----------W-------
--------------------------AGTTLLWATLPTAEPSCQGV-QCKAGEHCQGVGG
KTRCVTQSRAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 652)

CRAQGDPHYTTFDGRRYDMMGTCTYTMAELCGK--DETLPAFSVEAKNE
RRSSRLVSYVGLVTVRAYSHSVTLARGEVGFARIDNQRSRLPASLSKGRLRVYQRGTQAV
VELT----FGLVVTYNWDCQLTVSLPKSFQDQVCGLCGNYNGDPADDFLMP

ENSGT00760000118896_8_Linker_4_8 (652, 713)

DLEQ-----
--------AASPDEFASSWRLDDGDYLCSHGCQSSCPACTKGQAQHYEGSRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLPK
GPFAACHESLNPRPFLEDCVYDLCVTRGERLSLCRGLTAYAQACVELGISVEDWRSPAK

ENSGT00760000118896_8_Linker_8_9 (780, 786)

C
PMSCP

PF01826 // ENSGT00760000118896_8_Domain_9 (786, 838)

-NSRYELCAPPCPATCNSEAVPSNCSDHPCVEGCVCQSGFVASGGACVPASSCGC
VHEGRPLAPGQELWGDDLCRQRCTCDGAT-QKVTCRNTQGCPQGERCRVENGLLGCYPDN
FAS

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQASGDPHYISFDGRRFDFMGTCTYLLVGSCGQD--AELPTFRVLVENEHRGVQTVS
YTRAVRVEARGVKLALRREYPGKVLVDGILHYLPFQAADGQVQVFRQGNEGFVRTDFGLT
VTYNWNALVTAKVPGSYAKALCGLCGNFNGDPADDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

GGGQAA-------NALDFGNS
WQEEATP-GCGATDTGDCPK-------LDSLVAEQLESKE

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGIIADPNGPFRDCHATLD
PQGVVRNCVYDRCLLPGLSGPLCDSLATYTAACLAAGATVHPWRSEEL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-PS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYEACSYGCPITCGDLPVSGGCD-SECREGCECDDGFALSGES
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGSYYPPGQSFY--PGPGCDSLCHCEEGGLVSCQPSSCGPHEACRPSNG
ILG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVPVGATT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGQRFDFMGTC-VYVLAQTCGT-RPGLPQFTVLQENA
PWGN-GRYSATRVVTVIVGNYTLRLEQNKRK-VMVNGVDKKLPVELAGGQV---RVF-QH
GSDA-VIKTD-FDLH-VTYDLMYYVRVTVPGNYYKQMCGLCGDYNGDPKDDFQKPD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------LAANPNEFGNSWEEPVPNSPCVPKPD--CNPDEEDCKQ--KCS
AELEEKYQQEQF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGFLTS------------------------------------------
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-----------------------------------------------PTGPLAACHELIN
PQGSLKD---------------CVFDLCLGGGNISILC-------------------DNI
HAYVSICQEAGGR--------------------VEPWRTESF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
LPNSHYDLCADV------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CSLSCSALSAPL--QCPD---
---------GCAEGCECDPGFLYNGQ------ACVLI----QE

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCYHNGAYYEPEEMVL
ID----------------------NCQQKCVCHVSKG----------------------M
VCQDHRCNPEEVCELSGGI------LS

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CITKDPCHGVTCRPQETCK-----------EQN
GQGVCVPNYDVT

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWLWGDPHYHSFDGW----------------EFDFQG-TCDYVLAAV-
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
---------------------------GCPGVSAEGLTPFTVTTKNKNRGNPSVSYVNRV
TVSALGTNISIHKDEVGKVRV-NGMLTALPVSVAHGQILVTHGPGKAVLVADFGLQVSYD
WDWRVEVTLPSSYHSAVCGLCGNMDLNPGNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5619)

TLAP-----SVPLWGGSWRVPSW
DPFCWDEC---QGSCPTCPEDQQQEYEGPSFCGPLVPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

PGGPFATCHAHVPPESFFKGCV
LDVCLGGGAQDLLCQALAAYAAACQAAGIVIKDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIP

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPDNSHYELCGPRCPAS
CPSPSAPTTPAVCDGPCIEGCQCDEDFVLSAELCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

NGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYYEAGSEFLADG
TCSQLCRCGP----QGGSLVCTPASCGLGEECALLPSGQYGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYITLDGRQFDFQGTCEYLLSAPCDTP-PKGTENFTVTVTNEHRGS--QAV-SY
-----TRTVTLYVYNHVLTLSALWPQRLKV--------DGELVALPFNLGS-NLRAYLSV
S--DVVVTTDFGLSLSFDGNSFVKLHVPAAYAGALCGLCGNYNKDPSDDLTAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GNPS--
------GWQVGGALDCK-ECVPGPCPDPCTPEEQESFAGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6126)

CGVIS
A-PDGPLAPCHTLVSP-EHYFKGCLLDACQAQGHLGGLCPAVAAYVAACQAA--------
-----

ENSGT00760000118896_8_Linker_82_83 (6126, 6129)

AFL

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPVNSHYELCGNSCPVSCPSLSEPEG-CEP--TCREGCVCNSGLVLSGGTCV
PVDQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHDGRYYLLGAAFYPGPECERRCECGPGGQVTCQEGAACGPHEECRTEDGVQA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HPTGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYITLDGRVY-DLH-------GSCSYVLAKVCHPKPGEEDFSIVL
EKNKDGE-PQRVLVTVVDQVVSLAGGP--KVTVDGEDVTLPVA--VGRVQVTAEGRNIVL
QTTKGLRLLFDGDTHVLISIPSPFQGRICGLCGNFNGNWSDDFTLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GDVAPSVEAFGTA
WHAPDS--SQGCIEGCGPQGCPVCLAEETAVYESNQA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGQLQDPKGPFSTCHNVLKPSEY
FRQCVYDQCAAKGDKAFLCRSLAAYTAACQAAGGSVKP-WRTDSF

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPL-------E

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTHSC----QDSCAALSGFTGCTTRCFEGCECDDRFLLSEGVCVPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHNG
RYLPVNSTQLSADCSECCSCSSSIGLTCQAASCPEGQVCDLQEGSWV

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CRAASG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6819)

CSLSV
GANLTTFDGAHHAVGSA---GTYEFSSRCPGVQE-NIPWYRVVADVQPCQNNVKAVSTVH
IFFQDGIVTVTANKGM-WVN-GLRV----GLPAEVLTSVSVKRGSDGSILVHQKEGVQVR
LGSDGHLDVMVGDDHAGMLCGACGNFDGDRTNDLDDSQGETVMEKWKAPDFSPCHN----
-

-MCEEDWISGPTTVFSQPGLTQEASVDLKNTGRNEFLTAFLQNYQLAYSKAYPRLLISSL
SES-------PASVFILSQADKTSHNVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSD
HAISVQALNAKPDTAEL

PF17517 // ENSGT00760000118896_8_Domain_0 (138, 438)

TLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGATGASVSVT
LKGSVTFNGKFYPAGDVLSVTLGPYNVAQLQSSLDLSGSKVTASSPVAVLSGHSCAQKHT
TCNHVVEQLLPTSAWGTHYVVP-TLAS----QSRYDLAFV-VASQTTKLTYNHGGITGSR
GLQAGDVVEFEVRPSRPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYV
VKSVPGSEGVALVVAQTKAISGLTI--DG-HAVGAKLTWAAVPGSEFSYAEVELGTADTI
HT---AEATTNFGLLTF

ENSGT00760000118896_8_Linker_0_4 (438, 492)

GLAKATGYATAADCGRTVVSPAKPSCEGV-QCAAGQHCQVAGG
KAKCVAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 653)

CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGD--DDTLPAFSVEAKNE
HRGSRRVSYVGLVTVHAYSHSVSLTRGEVGFVLVDKQRSRLPVSLSEGRLRVYQSGPRAV
VELV----FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLLPE

ENSGT00760000118896_8_Linker_4_8 (653, 713)

GDL-----
--------APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRL

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTKLD
GPFAVCHGTLDPRSFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGNWRPLAN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLS

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSRYELCGPACPASCNEAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS

ENSGT00760000118896_8_Linker_9_10 (838, 839)

C

PF12714 // ENSGT00760000118896_8_Domain_10 (839, 896)

GC
TFQGLQLAPGQEVWADESCRRRCTCNGAT-HQVTCRDTQGCPAGEICSDQNGLLG

ENSGT00760000118896_8_Linker_10_11 (896, 904)

CYPNR
FGT

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1060)

CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN--AALPAFRVLVENEHRGSQTVS
YTRAVRVEARGVKVVVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT
VTYNWDARVTAKVPSSYAEALCGLCGNFNGDPADDLALR

ENSGT00760000118896_8_Linker_11_13 (1060, 1121)

GGGQAA-------NALAFGNS
WQEETRS-GCGATEPGDCPK-------LDSLVAQQLQSKN

PF08742 // ENSGT00760000118896_8_Domain_13 (1121, 1189)

ECGILADPQGPFRECHSKLD
PQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEKL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-LS

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPNS---------HYEACSYGCLLSCGDLPVHGGCG-SECHEGCVCDEGFALSGES
CLPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVHQGTYYPPGQTFY--PGPGCDSLCHCQEGGLVSCEPSSCGPHEACRPSGG
TLG

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVAVGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQASGDPHYTTFDGRRFDFMGTC-VYVLAQTCGT-RPGLHRFAVLQENV
AWGN-GRVSVTRVITVQVGNFTLRLEQRQWK-VTVNGVDMKLPVVLANGQI---RAS-QH
GSDV-VIETD-FGLR-VAYDLVYYVRVTIPGNYYQLMCGLCGNYNGDPKDDFQKPN

ENSGT00760000118896_8_Linker_19_22 (1497, 1573)

GS--
-----------------QAGNANDFGNSWEEAVPGSPCLPPPT--CPPGSEGCDTS-KCP
PEQEKKYQKEEF

PF08742 // ENSGT00760000118896_8_Domain_22 (1573, 1640)

CGLLSSATGPLASCHKLVDPQGPLQDCVFDLCLGGGNLSILCSNIHAY
VSACQAAGGHVKPWRTETF

ENSGT00760000118896_8_Linker_22_24 (1640, 1665)

CP---------------------MK

PF01826 // ENSGT00760000118896_8_Domain_24 (1665, 1718)

CPANSHYELCADTCSL
GCAALSAPLQCPDECAEGCQCDAGFLYNGEACVPIQQ

ENSGT00760000118896_8_Linker_24_25 (1718, 1719)

C

PF12714 // ENSGT00760000118896_8_Domain_25 (1719, 1772)

GCYHNGVYYEPEQTLLIDDCRQ
QCTCHAGKGVVCQEHSCKPGQVCQPSGGILSCITK--DPCDGVTCRPQETCKEQGGQGVC
VPNY------------------------------EAT

PF00094 // ENSGT00760000118896_8_Domain_31 (1838, 2347)

CWLWGDPHYHSFDG----RAFDF
----------QGTCNYVLAT--------TG-C-------PGVNTQGLTPFTVTT-----K
-----NENRGNPAVSYVRVVTVS--AL-GTNISIHKGEIGKVRVNGVLTA----------
------------------------------------------------------------
---------------------------------------L--------------------
------------------------------------------------------------
----P----VSEANGRISV----THGA--SKALLV-------------------------
------------ADF-G----LQVSYDWN--WRVDV-------------------T--LP
SSYHGA---VCG-LCGN-M--DRNPSN---DQA-FP------------------------
----NG

ENSGT00760000118896_8_Linker_31_32 (2347, 2436)

TLAPSIPIWGGSWR-------------VPGWDPL---CWD-------VCPGSCP
TCPEDKLQQYEG-------------PGFCGPLVPG

PF08742 // ENSGT00760000118896_8_Domain_32 (2436, 2555)

AGGPFTTCHAH---V--PPE-SF--
FKGCVL---DVCMGGGAHDI----------------LCKAL------A------------
----------SYMAACQAAGVVIEDWRAQVG---

ENSGT00760000118896_8_Linker_32_33 (2555, 2561)

CE--IT

PF01826 // ENSGT00760000118896_8_Domain_33 (2561, 2636)

CPEN--SHYEVCG---PTCP
A-SCPSPAPPATP----AVCEG-PCVE----GCQCDAGFVLSAD---RCV---PL

ENSGT00760000118896_8_Linker_33_34 (2636, 2640)

NNGC

PF12714 // ENSGT00760000118896_8_Domain_34 (2640, 2793)

G
C-WANGTYHEAG-----SEFWAD--GTCSH-----------RCR-C-GP--G-GGSLVCT
PASCGLGEV-CGLLPSG-------------------------------------------
----------------------------QYGC

ENSGT00760000118896_8_Linker_34_23 (2793, 2804)

QP----VSTAE

PF00094 // ENSGT00760000118896_8_Domain_23 (2804, 3742)

CQA-WGD--PHYI---T
LDGHRF--------------------------DFQG--NC-EYLL----SAPCHELPSGA
A-----------------NFTV----TVANE-HR-GSQAVS-------------------
-------------------Y----T---------R---S---V------T--L-------
Q---I---Y---N---H--S------L------T-------L------S--A---R--W-
------------------------------------------------------------
-----------------------------------------------------------P
---R---R--L-------------------Q-------------------------V---
D--G---V---F--V----------A---L---P-----F---H---L------D--S--
-L---L-------------H--A---H---L--S---G---A---D--V-----------
-----V-----V--T---T---T---S--G---L------S---L---------------
-----T---F---D---G--D---S---F---V---R----------------L----R-
---------V---P--A---A---Y-----A--G---A---L--C---G-----------
-------L---C--G-------------N---Y---N---Q----------D--------
-----------------------------------P---A---D---D------------
-----------------L--------------K---A---V-------------------
----------------D----G---K---P----------------------------------------------------------------------------A---G-----W---Q----V---G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAPGCGECVS------------G---PCPSQCTPEQQESFGGPNACGV---------------ISATDGPLAPCHGLVPPAQYFQG---------------CLLDACQVQGHPGGLC-------------------PAVAAYVAACQAAGAQ--------------------LGEWRRPDFCPFQ-------------CPAHSHYELCGDS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CPVSCPSISAPE--GCES------------ACREGCVCDAGFVLSGD------TCVPV----GQCGCLHDDRYYPLGQTFYPG---------------------PWCDSLCHCREGGL----------------------VSCQPSSCGPHEACRPSGGT------LGCVAV-------------------------------------GSATCQASGDPHYTTFDGR----------------RFDFMG-TCVYVLAQTCGTRPG---------LHRFAVLQENVAWGNGRVSVTRVITVQV--------GNFTLRLEQRQWKVTVRADGEQ-----------------------------------------GV-R-V-L-K-T-S-I-H-G-S-A------------------------------S-K-ID-R-I--R-P-G---------------L-W-P-T-TL-V-L-L-C-AG-S-L-P-G-NY-Y----S-----R-MC-G-W--L-T-AG-Q-R-A-I-DF-G-H-S-G-GR-E-G-G-GR-L-L-L-R-H-PP-A-A-R-S---RA-A---------H-S-KC-S-S-G-----RS-S-G-G-L-S-QR-T-G-R-L-A-L-H-K-L-V-D-Q-V-AL-I-R-L-A-C-T-AI-----------QQCGCYHNGPEQT--LLIDDCRQQCTCHAGKAVLCQEHSCQPGQVCQPSEGVLSCITKGAG-------------------------LGWAGT-GADVTMDGGLTPFTVTTKNENRGNPAVSYVRVVTVSALGTNISIHKGEIGKVRVLNGVLTALPVSEANGRISVTHGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP-----SIPIWGGSWRVPGWDPLCWDIC---PGSCPTCPEDKLEQYEGPGFCGPLVPGAGGPFATCHAHVPPESFFKGCVLDVCMGGGAHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPPATPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSHRCRCGP----GGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST----------AECQAWGDPHYVTLDGHRFDFQGNCEYLLSAPCHEL-PSGAANFTVTVANEHRGS--QAV-SY-----TRSVTLQIYNHSLTLSAR

PF00094 // ENSGT00760000118896_8_Domain_37 (2804, 3742)

CQA-WGD--PHYI---TLDGHRF--------------------------DFQG--NC-EYLL----SAPCHELPSGAA-----------------NFTV----TVANE-HR-GSQAVS--------------------------------------Y----T---------R---S---V------T--L-------Q---I---Y---N---H--S------L------T-------L------S--A---R--W------------------------------------------------------------------------------------------------------------------------P---R---R--L-------------------Q-------------------------V---D--G---V---F--V----------A---L---P-----F---H---L------D--S---L---L-------------H--A---H---L--S---G---A---D--V----------------V-----V--T---T---T---S--G---L------S---L--------------------T---F---D---G--D---S---F---V---R----------------L----R----------V---P--A---A---Y-----A--G---A---L--C---G------------------L---C--G-------------N---Y---N---Q----------D-------------------------------------------P---A---D---D-----------------------------L--------------K---A---V-----------------------------------D----G---K---P------------------------------
----------------------------------------------A---G-----W---
Q----V---G--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------GAPGCGECVS---------
---G---PCPSQCTPEQQESFGGPNA

PF08742 // ENSGT00760000118896_8_Domain_55 (4107, 4243)

CGV---------------ISATDGPLAPCHGLVP
PAQYFQG---------------CLLDACQVQGHPGGLC-------------------PAV
AAYVAACQAAGAQ--------------------LGEWRRPDF

ENSGT00760000118896_8_Linker_55_56 (4243, 4260)

CPFQ-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PAHSHYELCGDS------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------CPVSCPSISAPE--GCES---
---------ACREGCVCDAGFVLSGD------TCVPV----GQ

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCLHDDRYYPLGQTFY
PG---------------------PWCDSLCHCREGGL----------------------V
SCQPSSCGPHEACRPSGGT------LG

ENSGT00760000118896_8_Linker_57_62 (4828, 4873)

CVAV-----------------------------
--------GSAT

PF00094 // ENSGT00760000118896_8_Domain_62 (4873, 4988)

CQASGDPHYTTFDGR----------------RFDFMG-TCVYVLAQTC
GTRPG---------LHRFAVLQENVAWGNGRVSVTRVITVQV--------GNFTLRLEQR
QWKVTVRADGEQ-----------------------------------------GV-R-V-
L-K-T-S-I-H-G-S-A------------------------------S-K-ID-R-I--R
-P-G---------------L-W-P-T-TL-V-L-L-C-AG-S-L-P-G-NY-Y----S--
---R-MC-G-W--L-T-AG-Q-R-A-I-DF-G-H-S-G-GR-E-G-G-GR-L-L-L-R-H
-PP-A-A-R-S---RA-A---------H-S-KC-S-S-G-----RS-S-G-G-L-S-QR-
T-G-R-L-A-L-H-K-L-V-D-Q-V-AL-I-R-L-A-C-T-AI-----------QQCGCY
HNGPEQT--LLIDDCRQQCTCHAGKAVLCQEHSCQPGQVCQPSEGVLSCITKGAG-----
--------------------LGWAGT-GADVTMDGGLTP

PF00094 // ENSGT00760000118896_8_Domain_70 (5440, 5558)

FTVTTKNENRGNPAVSYVRVV
TVSALGTNISIHKGEIGKVRVLNGVLTALPVSEANGRISVTHGASKALLVADFGLQVSYD
WNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG

ENSGT00760000118896_8_Linker_70_74 (5558, 5619)

TLAP-----SIPIWGGSWRVPGW
DPLCWDIC---PGSCPTCPEDKLEQYEGPGFCGPLVPG

PF08742 // ENSGT00760000118896_8_Domain_74 (5619, 5680)

AGGPFATCHAHVPPESFFKGCV
LDVCMGGGAHDILCKALASYVAACQAAGVVIEDWRAQVG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPENSHYEVCGPPCPAS
CPSPAPPATPAVCEGPCVEGCQCDAGFVLSADRCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

NNGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWANGTYHEAGSEFWADG
TCSHRCRCGP----GGGSLVCTPASCGLGEVCGLLPSGQHGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPVST----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5995)

C
QAWGDPHYVTLDGHRFDFQGNCEYLLSAPCHEL-PSGAANFTVTVANEHRGS--QAV-SY
-----TRSVTLQIYNHSLTLSARWPRQLQV--------DGMLVALPFQLDS-LLHAHLSG
A--DVVVTTTSGLSLTFDGDSFVRLRVPAAYAGALCGLCGNYNQDPADDLKAVD

ENSGT00760000118896_8_Linker_77_82 (5995, 6056)

GKPA--
------GWQVGGAPGCG-ECVSGPCPSPCTPEQQESFGGPDA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGVIS
A-TDGPLAPCHCLVPP-AQYFQGCLLDACQVQGHPGGLCPAVAAYVAACQAAGAQLGEWR
RPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPFQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYELCGDSCPVSCPSLSAPEG-CES--ACREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLYDGRYYPLGEAFYPGPECERRCECGPGGHVSCQEGAACGPHEECRLEDGVRA
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6249)

HATGCGR

PF00094 // ENSGT00760000118896_8_Domain_85 (6249, 6408)

CLANGGIHYVTLDGRVF-DLH-------GSCSYVLAQVCQPKPGDEDFSIVL
EKNAAGD-PQRLLVTVSGQVVSLAQGQ--QVTVDGEAVALPVA--VGHVRVTAEGRNVVL
QTTKGLRLLFDGDAQVLISIPSSFRGRLCGLCGNFNGNWSDDFVLPN

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GLAASSVETFGAA
WRAPGS--SKGCGEGCGPQGCPVCSAEETAPYESNKA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6513)

CGQLRNPQGPFATCQAVLSPSEY
FRQCVYDLCVQKGDTAFLCRSLAAYTAACQTD

ENSGT00760000118896_8_Linker_88_89 (6513, 6537)

SFCR---------ESLPPLSAALQ

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSVCTHTC----QGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCTHNG
RYLPVNSSLLTSDCSKRCSCSSSSGLTCQAAGCPPGRVCEVKAEARQ

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWAARG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6820)

CVLSV
GANLTTFDGARGATTSP---GVYELSSRCPGLQK-TIPWYRVVAEVQTCHGKTEAVGQIH
IFFEDGMVTVTPNKGV-WVN-GLRV----DLPAEKLASVSVSRTPDGSLLVRQKAGVQVW
LGASGKLAVMVSEDHAGKLCGACGNFDGDQTNDWRDSEGKSVMEKWRAQDFSPW------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MGSLWSCWAL----------W-------
--------------------------AGATLLWALLTPAEASCQGI-QCAPGQRCQMVSG
KAKCLAESTAV

PF00094 // ENSGT00760000118896_8_Domain_4 (492, 654)

CRAQGDPHYTTFDGHRYDMMGTCTYTMAELRSS--KDSLLAFKVDAKNE
HRSSNKVSYVRLVTVHAYNHTVSLIYGEVGLAKIDYQYSSLPVSLSEGLLRVHQSGTRGV
LELD----FGLVVTYDWDGQLTLSLPKRFQDQVSGLCGNYNGDPADDFLTPDG

ENSGT00760000118896_8_Linker_4_8 (654, 713)

KQ-----
--------APDVLNFTKSWKVNDQDLLCDDGCYGNCPSCIPSQAQLFKKDLF

PF08742 // ENSGT00760000118896_8_Domain_8 (713, 780)

CGMLTLPS
GPFADCHQFLDPKPFLEECVYDMCVTGGERLTLCRGLNAYAQACVDLGISVREWRSRTN

ENSGT00760000118896_8_Linker_8_9 (780, 784)

C
PLT

PF01826 // ENSGT00760000118896_8_Domain_9 (784, 838)

CPANSHYELCSPACPPSCNSEARPTNCSSRPCVEGCVCLPGFVASRGLCMPVSSCGC
IFQDRLLAPGQEVYADEKCHLRCTCDGAT-QKVICRNTTGCLPKEHCGVQNGSFGCFPEY
FRI

PF00094 // ENSGT00760000118896_8_Domain_11 (904, 1056)

CRASGDPHYMSLDERIFNFMGTCTYLFTASCGQH--PSLPDFKVFIENERRGSQSVS
FVRSVKLEALGIKLEVRREYQGKVLVDGILHYLPFQALGGKLVVFRQGKYAILRTNFSLS
VSYNWDTHVTAKVPSNYFNSVCGLCGNFNGDPRDD

ENSGT00760000118896_8_Linker_11_13 (1056, 1122)

LGKQIRAEAI-------DPRDFGKK
WLVSSHL-GCRTDEQHLCPD-------FNKGLVS--NITQN

PF08742 // ENSGT00760000118896_8_Domain_13 (1122, 1189)

CRIFTNISGHFKHCWRVPA
YNSAYIECAYDCCRMPGQTKPLCDTLATYTAICQSSGVIVYPWRTETL

ENSGT00760000118896_8_Linker_13_14 (1189, 1204)

CP----------
-MT

PF01826 // ENSGT00760000118896_8_Domain_14 (1204, 1267)

CPPHS---------HYELCQRGCPLTCGDQPVPGGCG-SDCYESCVCDEGYVLSGEA
CVPLAS

ENSGT00760000118896_8_Linker_14_18 (1267, 1268)

C

PF12714 // ENSGT00760000118896_8_Domain_18 (1268, 1324)

GCVYQGIYHAPGDEFY--PGPECNSLCHCDKGGLVSCQPSHCSPHEVCKVLDG
ILR

ENSGT00760000118896_8_Linker_18_19 (1324, 1332)

CVGEGSAT

PF00094 // ENSGT00760000118896_8_Domain_19 (1332, 1497)

CQVSGASHYTTFDGRHFDFMGTC-VHVLAQTCWT-RPGLKPFTILQENA
VQGN-KQVSVTKKITIEVANYTLQLEQNQWK-VKVNGVDMKLPVLLDEDRV---QAF-RH
GTDM-VIETK-FGLL-VSYDLKYSVRVKVPHNYYKHMCGLCGDYNDDPKNDFQKSD

ENSGT00760000118896_8_Linker_19_23 (1497, 1573)

GS--
-----------------QAASSNELGDSWEKAVPGSSCTPRPS--CKPGQA-CSP--KCY
PTLEKKYRGKEF

PF08742 // ENSGT00760000118896_8_Domain_23 (1573, 4243)

CGLITS------------------------------------------
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-----------------------------------------------PTGPLAACHKLLD
PQGPLQS---------------CVFDLCLGGGNQSILC-------------------SSI
HAYVSACQAAGGT--------------------VKPWRNQTF

ENSGT00760000118896_8_Linker_23_56 (4243, 4260)

CPME-------------

PF01826 // ENSGT00760000118896_8_Domain_56 (4260, 4724)

C
PPHSHYEVCADT------------------------------------------------
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---------------------------------------CSLDCSAITTPM--QCLT---
---------PCSEGCECDTDFLQSIT------TCVPM----EK

ENSGT00760000118896_8_Linker_56_57 (4724, 4725)

C

PF12714 // ENSGT00760000118896_8_Domain_57 (4725, 4828)

GCHYNGVYYEPEESVL
IE----------------------NCQQHCVCQPGKG----------------------M
MCQDHSCKPGQVCEPSGGV------LT

ENSGT00760000118896_8_Linker_57_59 (4828, 4873)

CVTKDPCQGVTCRSQETCT-----------EKD
GKGVCRANYESK

PF00094 // ENSGT00760000118896_8_Domain_59 (4873, 5558)

CWVWGDPHYHSFDGL----------------NTNFHG-TCSYLMAGT-
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---------------------------GCPGTGAEGLTPFSVITKHESQSDPKVSYVRKV
TVKTYNTSITIHEKKTGRVQV-NGVFMALPVYLAGGRISVINGGSKAVLETNFGLQVTYN
WKWRVHVTLPSSYYGAVCGLCGNMDKNPQNDQVFPNG

ENSGT00760000118896_8_Linker_59_74 (5558, 5612)

TMAP-----SIPTWGGSWQVPGW
DPLCWNEC---QGSCPTCPEDRVEEYRGPGF

PF08742 // ENSGT00760000118896_8_Domain_74 (5612, 5680)

CGPLDHDTVGPFTSCHAHVPPESFFEGCV
LDVCLGGQVKDILCQALADYAAACQAAGIKIEDWRTQAG

ENSGT00760000118896_8_Linker_74_75 (5680, 5684)

CEIT

PF01826 // ENSGT00760000118896_8_Domain_75 (5684, 5738)

CPVNSHYELCGPPCPAS
CPPPARHTAPTACDGPCVEGCQCDKGFVLSADQCVPL

ENSGT00760000118896_8_Linker_75_76 (5738, 5742)

DGGC

PF12714 // ENSGT00760000118896_8_Domain_76 (5742, 5803)

GCWVNGTYYEAGTEFWADT
TCSKRCHCGP----GGDSLVCKPASCGLGEECALLASGEIGC

ENSGT00760000118896_8_Linker_76_77 (5803, 5820)

QPISI----------AE

PF00094 // ENSGT00760000118896_8_Domain_77 (5820, 5992)

C
QILGDPTYITLDGHRFDFQGTCEYLLSAPCHAP-PTGTEYFNVTVVNEHRCS--QAV-SY
-----TRSITLRIYGLSLTLSAHWPKNLLV--------DGEMVKLPFQLQS-RLLVHLSG
M--GLVVHTSWGLSLTFDGNSFMRLRVPAAYAGTLCGLCGNYNKNPNDDLT

ENSGT00760000118896_8_Linker_77_82 (5992, 6056)

AVGGKPE--
------GWKVGGFPDCD-QCQLRTCPKPCTPEERKRFGGPNA-------------

PF08742 // ENSGT00760000118896_8_Domain_82 (6056, 6125)

CGIIT
A-PEGPLAPCHSFVPP-TQYFEACLLDTCQVQGHSGGLCPAIATYVAACQDARVRLREWR
KPDF

ENSGT00760000118896_8_Linker_82_83 (6125, 6129)

CPLQ

PF01826 // ENSGT00760000118896_8_Domain_83 (6129, 6185)

CPAHSHYQLCGDSCPVSCPSLSAPVG-CET--ICREGCVCDAGFVLSGDTCV
PVGQ

ENSGT00760000118896_8_Linker_83_84 (6185, 6186)

C

PF12714 // ENSGT00760000118896_8_Domain_84 (6186, 6242)

GCLHQGRYYALGATFYPGYECEWFCECGPDDQVTCRI-ETCGIHEECRIEDGIRS
C

ENSGT00760000118896_8_Linker_84_85 (6242, 6254)

HPKSSKLMLVLH

PF00094 // ENSGT00760000118896_8_Domain_85 (6254, 6408)

GTHYATPDGLVY-DLY-------GSCSYILAQVCFPKHGEEAFSIVL
EKDLAGN-PQRVVVTVAGQVVVLAKGP--QVTVDSEVVALPMV--VGSIYITAENRNVFL
QTKSGLKLLFDGDDHILISIPSPFRGRLCGLCGNFNGNQSDDFVLPS

ENSGT00760000118896_8_Linker_85_88 (6408, 6458)

GVVAPNVEAFGAA
WRAPGS--SLGCGEGCGPQGCPVCSAEKRELYEENDA

PF08742 // ENSGT00760000118896_8_Domain_88 (6458, 6526)

CGKIRDPQGPFAACHKALNHSEY
FHQCVFDLCTHHGDRDYLCRSLAAYTAACQAAGAAVKP-WRTDSI

ENSGT00760000118896_8_Linker_88_89 (6526, 6537)

CPA-------E

PF01826 // ENSGT00760000118896_8_Domain_89 (6537, 6594)

CPAH
SHYSICTHSC----QGSCAAISGFTGCTTQCFEGCECDDHFLLSQGVCIPAQD

ENSGT00760000118896_8_Linker_89_90 (6594, 6595)

C

PF12714 // ENSGT00760000118896_8_Domain_90 (6595, 6648)

GCFYND
QYMPVDSSLMSSDCSERCFCSPNNGLTCHEAGCPSGRVCEIQAGVRG

ENSGT00760000118896_8_Linker_90_91 (6648, 6656)

CWPAKG-L

PF00094 // ENSGT00760000118896_8_Domain_91 (6656, 6817)

CTFSV
GGNLITFDGAFNPISSP---GVYELSSRCPGLLK-NVPWYRVLADVQPCHDNDKIVSKVH
IFFQDGMVTVIPSKGT-WVN-GLRV----DLPATVLTSVSVRRMPDGSMLVHQKAGVTVW
LGKDGLLDVMVGDNHAAMLCGACGNFDGDRNNDVHKNQKTISIETWRAQDFSPCAN----
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