Query Results 

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-----------------------------------AYSPSHNGQV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DIFHFPGLCNYVFSSHCKSPYEDFNVQIRRSPGPNATTAVSRVTLKLEGTVLEMSLGAIL
VNG---------KPAQLPFSQAGILIEKSSTYVRVVAKLGLVFL-WN-QD---DGIL---
----LELDAKYANQTCGLCGDFNGVP

ENSGT00760000118896_5_Linker_0_4 (267, 333)

TYNEF---------FSNNVRLTAAQFGNMQKLDG
PTEQCQDPLPAA-PHNCM--D---------PF

PF08742 // ENSGT00760000118896_5_Domain_4 (333, 409)

DICETVLRSAPFFACHALVDVGSYVEAC
RQDACGCDEG---Q--RAACICGTVAEYSRQCAHAGGLPADWRAPELC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--KT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPGNMQY
RECGSPCVD-----TCSNHEQSPLCEEHCVDGCFCPP---G---------TVFDDISGQ-
---GCVPVNR

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CFCTYKGQPYAPGAFYSTECTNCTCSGGQWSCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVTGGSHFS
TFDEKHYTVHGDCNYVLV-KPCDDKAFTVLTELRKCGLTDSETCLKSVSLSIGQTVIV-V
KSTG--EVFVNRIY--TQLPVSAGNATLFRPSSSFIIAQTNL-GLQLTIQLSP-IMQVFV
RLEPSLQGLTC-----GLCGNFNNVQADDFRTMSGVVEGTAA-AFV------NTYKTQAD
CPNVKNHFEDP-------------------------------------------------
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--------------------------------------------------------CTLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

KYAQHWCGLLT-DRQGPFALCHAVVSPALYHRNCMFDTCNCEKSEDCLCAALSSY
VQACAAQGVLLSGWRT-GV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CTKSM-S

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSLMYHYHITTCQPTCRSLSE-PDVTCGIKFV
PVDGCACQEGTFMDDTGKCVPLAS

ENSGT00760000118896_5_Linker_15_17 (1525, 1586)

CPCYYQGSALPNGESVHDNGVICTCTQGRLNCIGGQ
VP-KP---VCTAPMVYFDCRNASAG

PF01826 // ENSGT00760000118896_5_Domain_17 (1586, 1638)

ATGAE-CQKSCHTLD---MAC--YNSQCVSGCVCP
DGLVSDGEGGCIH-KDQCPCVHNEANYQPGETIQVECNT-------C----TCKNRMWEC
TKEPCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CAVYGDGHYITFDGQRYSFSGNCEYTLVQD--HCGKNSSGKGTFRVITENIP
CGTTGTTCSKAIKIFLG-----------------------------------SYELKLSE
GKVEAMEKEGAKGEPPYSIRQMGIYLIVDTNAGLVLLWDKKTSIFIQLSQDFKGKVCGLC
GNYDGNTVNDFTTR

ENSGT00760000118896_5_Linker_20_26 (1875, 1920)

SLSVVGDV-------WEFGNSWKLSPTCPDTVPVRDPCTANPYRK

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1996)

A
WAQKQCSIINSAVFSACHP--HVEPTKYYEACVSDACACDTGGDCECFCTAVAAYAQACN
EISICVSWR-TPSICPLFCDYYNPNGSCEWHYQPCGAPCMKTCHNPSGKCSHNVRGLE--
--GCYPKCPPEAP--IFDEDKMECVQ--SCAP---------CYIRGRY------YPP-GS
PVPSDENCHSCS--------CTE-AGIKCTYDSK----ACVCTYEGRSFHPGEIIYHTTD
GTGGCITATCSANGTIVGKVYDCDLTTTA--P---STTFSFS--HTTLEYVTTPLPMTGP
TVIWGYTKS---------------------------------------------FAVPT-
------THTGVTTMVF------RESI--STPS----------------------------
------------------------------------------------------------
----------TKSEATECVK----------------------------------------
----------------------------------------------------------EV
CTWSPWLDVSHPGTGANSGDFDTLENIRAEGYRVCSSPR---GVECRAAEFPAVPWQELN
QTVECSTTQGLICHNKDQAS--G-KCENYQIRILCCASQP--CEPSTVRAPTTEPHSQST
VTP--------------AIS-----TSSPS------------------------------
------------------------------------------------------------
-------------------TT--------------------------PEPGSHS------
---------TKT--------TASPTT--TKENETRESHSS----SPK----TSENSSHSP
KVT---SSKVRRVSVTNPCLQEICEWTAWIDGSYPSPDINGGDFDTFKNLRSEG-YQFCD
VP---TEVECRAKSFPNIPLKELEQ-N-VTCSKTEG-LVCLNKDQL----PPICYN---Y
-EIRIKCCWKENVCGPKVETTSRAYTTQT----PKSHGVTKITTGQKPTVKATCTTSPTT
PTTTSVTTKPSPET--TSHSVPTTTTSPPTSPQTPTTSVSTS-----PTTTPS-------
-TSTHPPT--PS-----------------TK---------------SSPETTSHSVPTT-
TTSPSSSP------------QTPTTS-----------VTT------SPTTPTTTS-----
-------------------------------------------VTTKPSP-KATS-----
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----MGAPSGCLALAWALAALLLVQKSETQGGVQPSW----ASTE--------------A
AANS-------PWVDAAWSVTVIPPVTILP--TMSFLNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 281)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSTHCGAAYEDFNIQLRRGLAGSRP-TITHVVLKTQGLVLEASNGSVL
INGQR---------EELPYSRAGLLVEQSSVYLKVTVRLGLTFL-WN-RE---DSAL---
----LELDPKYANQTCGLCGDFNGLPAVNEF---------

ENSGT00760000118896_5_Linker_0_4 (281, 332)

YSHNARLTPLQFGNLQKLDG
PTEQCQDPPPSP-ANNCTDR-----------

PF08742 // ENSGT00760000118896_5_Domain_4 (332, 409)

EGVCRRTLLGQAFAECNALVDPAEYVAVC
TQDLCRC------P----TCPCATFAEYSRQCAHAGGRPQNWRGPDLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMRH
QECGSPCAD-----TCSNPERSQLCEDHCVDGCFCPPG------------TVLDDVTHG-
---GCLPLER

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGHTYAPGASFTTSCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGSHIS
TYDERLYDVHGDCSYVLS-KKCTGDLFTVLAELRTCGLTDNENCLKSVALSMNGGDTI-I
QIQANGGVFINSIY--TQLPVSAANITVFRPTSFFILVHTGL-GLQLQVQLVP-LMQVFL
RLDPSYQGQMC-----GLCGNFNQNQADDFRALSGVVEGTAA-AFA------NTWKTQAA
CPNVKNSFEDP-------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

NYARHWCSLLT-DPAGAFSRCHSILNPAPFHSNCMFDTCNCEKSEDCLCAALSSY
VHACATKGVLLSSWRD-GV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CTKYMSS

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQNYTYVVDSCQPTCRALSQ-VDVTCGVSFV
PVDGCVCPSGTFLDDAGACVSAEA

ENSGT00760000118896_5_Linker_15_17 (1525, 1573)

CPCYFHSSVVAPGEVVHDNGVVCSCAGGKLSCLGAA
EQKSS---GCTA

PF01826 // ENSGT00760000118896_5_Domain_17 (1573, 1638)

PMVYLDCSNASAGTPGAE-CLRSCHTLD---VDC--FSTHCVSGCVCP
PGLVSDGSGGCVA-EEDCPCLHNEAAYKPGETIRVACNT-------C----TCKNRRWEC
SHKPCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CVAYGDGHFITFDGERYSFEGSCEYTLAQD--HCGGNGTANGTFRVVTENVP
CGTTGVTCSKAIKLFLE-----------------------------------NYELILHE
GTYKVVQRG-PGRGLPYKVRYTGIYLTVETQSGVLLSWDRKTSVFIRLRQDYKGRVCGLC
GNFDDKGVNDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1920)

QSVVGSA-------LEFGNSWKFSPSCPDAPAPRDPCTANPYRK

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1996)

S
WSQKQCSIINSATFAACHS--QVDPTKYYEACVGDACACDLGGDCECLCTAVAAYAQACR
DVGVCVSWR-TPDICPLFCDYYNREGQCEWHYQPCGAPCMRTCRNPSGHCQMDLPGLE--
--GCYPRCPPSEP--FFSEDQMKCVA--QCGC---------YDEDGNY------HDV-GA
RVPAAENCQSCE--------CTA-GGLRCTHSLE----ACTCVYEGQTYHYEDVIYNTTD
GLGACLIAICGHEGRIIRTTMECPGTP----STT-PFTFTTT--AAPLST----------
------------------------------------------------------------
-----------------------------TGS----------------------------
------------------------------------------------------------
----------GPTSPTVCVR----------------------------------------
----------------------------------------------------------EL
CL

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2616)

WSDWYDSGRPEPGMAGGDFETFVNLRQRGHQVCPAPA---SIECRAQGLPDTPLQQLG
QKVECDMAQGLTCLNAEQSP--P-LCHNYEVRVLC

ENSGT00760000118896_5_Linker_28_29 (2616, 2905)

CDYVP--CSTSPGTTSLQTP-----
----------------------------------------------------TES-----
--LPTPR-----------------------------------------------------
T-----QTPPAEPTTTGTWAPS--------------------------------------
------------------------------------------------------------
----------SSATLATTSCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3008)

QWTEWFDEDYPKSEEAGGDVESYDRIRSAG-GAVCE
QP---QDIECQAENFPGRSPESLGQ-R-VHCDVSFG-LVCRNQEQV--GLFKMCYN---Y
-RIRVFC

ENSGT00760000118896_5_Linker_29_33 (3008, 3294)

CS-HDHCEQPTSQPLTQTPPL--------------------------------
------------------------------------------------------------
------------------------------RTTGGPSSG-----PTPV------SRTTQI
LVTP-TTGTVSTG----PPSTSHTEMHTT-------------------------------
----------------RA---KTSLETL----VTATTEATSSQGTTSCQP-QC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3392)

EWT-DWF
DVDFPTSGVEGGDMETFENIRI-AGGTLCQEP-Q---RIQCRAENYPEV-SIDQIGQVLT
-CSLHMGLICRNQDQKGPFNMCFNYNVRVLCCHPSPHCPSTAVPST-ASTTLSIQTHASS
PEATS--------------------------------------TASSP------------
------APQTTR--------------------------------T---------------
-----------------LVTPS-----TMATTIF--------------------------
-----------------------------------PSVPV----------------TRVS
TGS----------------PRSSES----------PTWHPKT------------------
------------------------------------------------------------
-----SPGQPTTLP---------------------------GTAQ---------------
---------------------------A---------TSSTR-------ASPSPPTIQAT
------------------------------------------------------------
------------------------------------------------------------
-------------------------------SSPW-------------------------
------------------------------------------------------------
-------STTIRLSAGTSRA--TAPTGKTQTSLLVTSSHTQSPTSPGARSTACEPRCA

PF13330 // ENSGT00760000118896_5_Domain_37 (4199, 4293)

WT
DWIDESYPTPGVSGGEFETYTNVRADGKAICKH-PL---DLQCRAVTLPDNTLEMVGQVV
HCGLPEGLVCRNQDQDDWLKMCLNY-KIRVLC

ENSGT00760000118896_5_Linker_37_39 (4293, 4502)

CEDYSH--CASTLATTVVSPRGTSP---
------------------------------------------------------------
------------------------------------------------------GLTPT-
------------------LATSTTVQPPMTPSPMAPST---GRTV--ATST----CQPTC
-

PF13330 // ENSGT00760000118896_5_Domain_39 (4502, 4654)

HWTKWM-----DSDQPLPGRYGGDIE--TYYHI----QDAGGQLCE---------EPEA
I--------ECQAVLYPDTPLE--------------------------------ELDQVV
YCDVSYGLICRN--NRQRGGRPCLNY-HIRVLCCEEDSNCVSSPRPQPTTTSTSIST---
------------------------------------------------------------
------------------------------------------------------------
-------------SI----S----------------------------------------
----------------------------TSISTS--------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TSQRSPEV-------TGLKSTATLPSSP-----
-----RTTQR---------------VP---------------------------------
-------------------------------------------------------TST--
---TQTFLSSFGTTEGV--------TVSTTQIGSSSP-----------------------
---------QT-------------SQR-----VTASTTQTGPSSPGTSQ-----------
------------------------------------------------------------
------GVTAS------------------------------------TI----QTGP--S
------------SAVTSQGVTTSTTQTGPSSPATSQRLTAS----T------TQIGPSSA
VTS---QGVT---TSTTQT-G-------------P------------------SSPGTSQ
G-------VTAS--TTQTGPSSP--AT------SHRLT-V-------STTQIGPSSP-GT
SQ-------RVSESTTQ---------------------TLPTPARTTE-RVSSLS--PSA
SPR----------LPTTITKPTSPSAPTSGPVVTSSRWISSKSPPSTPTFGT--------
------TSV---SRSPQP--------SPST------HTLATSSSTGCSPRC

PF13330 // ENSGT00760000118896_5_Domain_44 (5812, 5925)

TWT------
DWFDEDYPTPGL-DGGDFETFSVFRS-AGLSFCQHPQ---DIQCR-SEKAPDTRLEDLGQ
VVRCN-----------VSFGLVCRNREQPGPLRYCHNYHVRLLCCEDN------------
-----GH-CPTATTTST--APL-----------TSPKVFST-T-----------------
SSTGQS------------------------------------------------------
--------------------------------------------------------SPRV
TTPQTT-ATLPSSP--------RTTQRVPT------STTQTFPSSFGTTEGITVSTTQTG
PSSPGTTKKVTV----------STIQTVPSS--------------------------PET
TQGVTASTTQTAASSTGITKRVLVSTTQ-T------------------------------
--------------------------------------SPSSLRTSQGVTT---------
-------------------------------STTQTGPSSSGTTEKVTV-----------
-----S-----------------------------TTQTVPSSPGTTQEVTVSTTH----
--TGPSSPQ------------ITKRVLISTTETGPSSPGT-------------SQRITAS
TTQTVPSP--------------------------PVTTEKATVS---TIQTVPSSPETTQ
GVTVSTTQTGTSS-TRITKRVL------------VSTTQTGPS-SSGTTEK---------
-------------------------------------VTVSTTQTVPSSPGTTQEVTVST
T----------------QTGPSSPGITKKVL-----------------------------
------VSTIQTG------PSSPETTQGVTVS-TTQT-----------------GTSS--
-----TRITKRVLVSTTQTSPSSSGTTEKVTVSTT-------------------------
---QTVPSSPGTSQKVTASTTQTGPSSPGTSQG------------------VTTS----T
TQTGPSSPGTSQRVSESTTQTLPTPARTTER-------------------------VSSL
SPSASPRLPTTITKPTSPSAPT--SG-----PVVTSSRWISSKS---------------P
PSTPTFGT----------T----SVSRSPQPSPS--------------------------
----------------------------------THTLATSSSTGCSPRC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7291)

TWTDWFDEDY
PVPGLDGGDFETFSVFRSAGLSFCQHP-Q---DIQCRSEKAPDTRL---EDLGQVVRRNV
SFGLVCRNREQPGPLRYCH---NYHVRLLCCEDNG-HCPT-ATTTST-APSTSP------
----------------------------------------------K--VFSTTSSTGQS
SPRVTTPQTTA-----TLPSSPRTTQRVPTST----------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TQTFPS--------------SFGTTEGITVSTT--QTSPSSPGTTK
K-----------------------VTVSTIQTVPSSPGITEK-----------VTASTTQ
TGPSSPGTTHEVTVSTIQTGPSSSGITKRVLVSTIETSP--SSPGTSQKITASTTQ----
TGPSSPGTSQRVPASTT-----------QTGPSSPQITKRVLISTTQTGPSSPGTTHGVT
EPTIQTGPSSPGTSKRFTT--STTQTGPSSPGTTEKATVSTI----QTGPSSTGTSQGVT
V-STTQTGPSSPGTSQGVTT----------STIQTGPSSPQITKRVLISTTQTGPSSPGT
THGVTEPTIQTGPSSPGTSKRFTTSTTQTGPSSPGTTKKAT------VSTIQTGP-----
---SSPGTSQGVTV----STI-----QTGPSSSGTSQRLTAST----TQTGPSSPGTTEK
A--------TVSTIQTGPSSPGTSQRLTASTIQ---------------------TGPSSP
QITKRVLISTTQRGPSSPGTTHGVTE----S-------------------TIQTGPSSP-
GTS---------------------------------------------------------
KRFTTSTTQTGPSSPGTTEKAT-------VSTIQTGPSSTGTSQGITVSTTQ--------
---------------T-GP---SSPQITKRVLISTTQTVPSSPGTS--------------
-QRLTASTTQTGPS----SPGTTEKATVS-TI-QTGPSSPGTSQ----------------
--------------------------------------------------RLTASTTQ--
--------TGPSSPVTSQGITVSTTQTGPSSPQITKRV----------------------
----------LISTTQIVPSSPGTSQGVTVSTIQTGPSSP-----------GTSQRLTAS
TTQIGPSSPGTSQ-RVSESTTQTLPTPARTTERVSSLS------PSASPRLPTTITKPTS
PSAPTSGPVVTSSRWISSKSPPSTPTFGTTSVSRSPQP---------SPSTHTL------
-----ATSSSTGCSPRC

PF13330 // ENSGT00760000118896_5_Domain_54 (8718, 8942)

TWTD-----WFDEDYPV---------------------PGLD-
-------GGDFETFSVFRSAGLSFCQHP----QDIQCR----SEKAPDTRLEDLGQ----
-------VVR------CNVSFGLVCRN------REQPGPL------RYCHN---------
------------------------------------------------------YHVRLL
CCEDNGHCPTATTSTASSS---------ALQTPRT-------------------------
------------------------------------------PVTP--------------
-----------------------------------------------TPRATTVFSSVP-
--IFHTSTASTGHPRSSESPTWHPGTS-------------------------------LG
RPSTLPSTAQA-------------TSSSGAS-TR--ASLSPPTPEATSSPWS-TVRLSA-
-----------------ASSLS----------P-ETT-HILPPVTVSTVSSA-VL---TT
PRP---ASSPSSHFT-TGCLCQA-F----GQL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--FSPGDVVYN------KTD--------RAGCHFYAICNQHCDIDRFQ-GTCPTTSPPES
SV----------STPPESSVSTPPESSVSTPPESSVSTPPESSVSTPPESSVSTPPESSV
STPPESSASMPPESSVSTPPESSVSTPPESSASRSPESSASTSPISPAPVCDLIVPPRQV
NESWTLSDCTRARCEGYN-HVILLGRK--PVPSIHCVNGHQPVKVWSENDPCD-FYFECE
C-----------------S

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CRGWGDSHYTTFDGTSYSFLDNCTHVLMKEIHPRHGNLSIY
MNNYYCRASA--A-TAHCPRALSIHYKSTEVILTI-SIDASGQEQSLILFDQIQVSSGFS
KNGMSVSVTGTTTMGIDIPAIGVNITFDGHLFQIRLSYSHFSHNTEGQCGTCTNNQNDDC
RQPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9979)

TMAPSCQHMALSWMVPE----SGREDCWAPTSPPPTAGTLPSA------------
--PTTP---TSTPCPPA-

PF08742 // ENSGT00760000118896_5_Domain_57 (9979, 10054)

PLCE--LI-------LSPVFEECHDLIPPGPFVSSCVSDSCQ
PD---RPQVLCQSLEAYAALCRARGVCSSWRNA

ENSGT00760000118896_5_Linker_57_58 (10054, 10064)

TDGLCNFT--

PF01826 // ENSGT00760000118896_5_Domain_58 (10064, 10143)

CPPDKVY----QPCGPA
QPASCDLRSQSGA--------G-----RGLAEGCFCPDGHTLFNKHTNVCV-RE-C----
-ACVGPDGFPKSPGERWVSDCQDCMCHPGSMSVQCTPLPCKAQDPPPQCSGAGFVAITRP
LGNNSCCLETLCVCNTTTCT-QSPPTCGPAEELVRTQKEDACCPTFSCRP--QLCFYNHT
------FFGVGATFPSV-TPCHTCTCLSMD---TRGPIVQCEENTCN-TTCRQGYEHRKV
AGQCCGECVQTACPTSDG------WLIQPN----ETWVNPLLDNCTEYRCEVQNGLHVLT
QR--PTPCPVV--S-----SCEGILRKIGCCYSCE-EV-D----------KCQVRVNTTV
LTHQGCTTHAPVNVTFCGGSCPG-VSKYSMEAQAMEHQCTCCQETVVHEEVVTMQCPDGT
AIQHTYTHVDKCSCAPSCGPSPKAPEDSTPVFPV--------------------------
-----------

----MGAPSVCRTLVLALAAMLVVPQAETQGPVEPSW----GNA----------------
---GHTTDGGAPTSSPTRRVSFVPPVTVFP--SLSPLNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-VVTRVVIKAQGLVLEASNGSVL
VNGQR---------EELPYSRTGLLVEQSGDYIKVSIRLVLTFL-WN-GE---DSAL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 339)

AFNEF---------YAHNARLTPLQFGNLQKLDG
PTEQCPDPLPLP-AGNCTDE-----------EGICHRT

PF08742 // ENSGT00760000118896_5_Domain_4 (339, 408)

LLGPAFAECHALVDSTAYLAAC
AQDLCRC------P----TCPCATFVEYSRQCAHAGGQPRNWRRPEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCTD-----TCSNPQRAQLCEDHCVDGCFCPP---G---------TVLDDITHS-
---GCLPLGQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGRTYSPGTSFNNTCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KKCADSSFTVLAELRKCGLTENENCLKAVTLSLDGGDTA-I
RVQADGGVFLNSIY--TQLPLSAANITLFTPSSFFIVVQTGL-GLQLLVQLVP-LMQVFV
RLDPAHQGQMC-----GLCGNFNQNQADDFTALSGVVEATGA-AFA------NTWKAQAA
CANARNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPNSAFSRCHSVINPKPFHSNCMFDTCNCERSEDCLCAALSSY
VHACATKGVQLSDWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKYMQN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQRYAYVVDACQPTCRGLSE-ADVTCSVSFV
PVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEDAVCSCAGGKLSCLGAS
LQKST---GCAAPMVYLDCSNSSAGTPGAE-CLRSCHTLD---VGC--FSTHCVSGCVCP
PGLVSDGSGGCIA-EEDCPCVHNEATYKPGETIRVDCNT-------C----TCRNRRWEC
SHRLCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CVAYGDGHFITFDGDRYSFEGSCEYILAQD--YCGDNT-THGTFRIVTENIP
CGTTGTTCSKAIKLFVE-----------------------------------SYELILQE
GTFKAVARG-PGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLC
GNFDDNAINDFATR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SRSVVGDA-------LEFGNSWKLSPSCPDALAPKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACRS--QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH
DAGLCVSWR-TPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLE--
--GCYPKCPPSQP--FFNEDQMKCVA--QCGC---------YDKDGNY------YDV-SA
RVPTAENCQSCN--------CTP-SGIQCAHSLE----ACTCTYEDRTYSYQDVIYNTTD
GLGACLIAICGSNGTIIRKAVACPGTP----ATT-PFTFTTA--WVPHST----------
------------------------------------------------------------
-----------------------------TSP----------------------------
------------------------------------------------------------
----------ALPVSTVCVR----------------------------------------
----------------------------------------------------------EV
C

PF13330 // ENSGT00760000118896_5_Domain_28 (2522, 2615)

HWSSWYNGHRPEPSLGGGDFETFENLRQRGYQVCPVPA---DIECRAGQLPDMPLEELG
QQVDCDRMRGLMCANSQQSP--P-LCHDYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCEYVP--CGPSPAPGTSPQP-----
----------------------------------------------------SLSAST-E
PAVPTPT-----------------------------------------------------
Q--------TTATEKTTLWVTP-------------------------SVRSTAA------
----------------------------------------------------LTSQTGSS
SGPMTV----TPSAPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTEWFDEDYPKSEQLGGDVESYDKIRAAG-GHLCQ
QP---KDIECQAESFPNWTLAQVGQ-K-VHCDVRFG-LVCRNWEQE--GVFKMCYN---Y
-RIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCR-DDHCRGRATTPPPTTELE--------------------------------
-----------------TATT--TTTQALFSTLQPTSSPGVTRAPPASTTAVP-------
-TLSEGLTS-P-----------RYTSTLGTATTGGPTTPAGPTEP-TVPEVATSSLPTR-
SALPGTTGSLGTWRPSQPPTLAPTTMATSRAHPTG--TAG-T----ASKGPGTTSLAPT-
-------L-TSKLSTSQAKTSTPRTETT----MSPLTNATTSQGTTRCQP-KC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDFPTSGVAGGDMETFENIRA-AGGKMCWAP-K---SIECRAENYPEV-SIDQVGQVLT
-CSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSS-TATPS--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STPGTTWILT------------------------------EPTTTA
ITTVAMGSTATPTSTLRTAPPPKV------------------------------LTTTAT
TPTVTS--SKATP---SSSPGT--------------------------------------
---------------------------------ATTLPAP-ISTATTPTAT---------
-------------SFTAIPS----------------------------------------
----------------------------SSLGTTWTR-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LSQA------TTPTATMSTAT-------------------------
------------------------------------------------------PSSTPE
TAHTSTVLTATATTTGA--------TGSVATP-SSTP-----------------------
---------GTAHT----------TKVLTT--TTTGFTATPSSSPGTAR-----------
------------------------------------------------------------
------TLPVWISTTTTP------------------------------------------
------------------------------------------------TNRGSTVTPSST
PGTTHTPTVLTTTTTTVAT-GS-----MATPSSST------------------QTPGTPP
PLTTTATMITAT--GSTTNPSST-PGTT---PIPPVST-T--------------------
---------MATTQGQS---------------------LPPSSPQTLPTAWTLATSGTLG
TTHITEPSMVTSHTPAATTGTTQHSTPALSSPHPSSRTIKSPPSPGTTTPGHTTATS--R
TTATATPSKTRTSTLLPS--------SPTS------APITTVVTTGCEPQCV

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WS------
EWLDYSYPMPGP-SGGDFDTYSNIRA-AGGAICEQPL---GLECR-AQAQPGVPLQELGQ
VVECS-----------LDFGLVCRNREQVGKFKMCFNYEIRVFCCNY-------------
-----VR-CPSTPATSS--MTT-----------PSSTPGTT-WILT--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------ELTT-AATTTASTGSTA-------------------
--------------------------------------TPSSTPGTTWILTEPTTT----
------------------------ATVMVPTGSMATASSTQATAGTPNVTT-MATTPTV-
----TSSKATPSSSPGTATTLPALISTATTPTA---------------------------
---------------------------TSFTAIPSSSLGT-------------TWTRLSQ
T----TTP--------------------------TATMSTATPSSTPETAHTSKVLTAMA
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------TTGATGSVATPSSTPGTAHTT
KVLTTTTTGF-TAT-----PSS---------------------------SPGTARTPPVW
ISTTTT--------------------PTTR-GSTVTPSS---------------------
--IP--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------GT-----------------------------------------TH---------
-----------------------------SATVLT-TTTT-VATGSMATPSSST------
----------------------------------------------Q--T----------
---------------------PGTPP---PLTTTATTI-TATGSTITPSSTPGTTPIPPV
LTSTATTPTATSSKATSSSSPRTATTLPVLT--TTTPTATSFTAIPSSSLGTTWT---RL
SQTTTPTTTMSTATPSSTPETAHTSKVLTVM-----------ATTTGATGSAATPSSTPG
TAH---TTKVLTTTTTGFTAT-PSSSPGTARTLPVWISTTTTHTNSGSTVTPSSIPGTTH
T-----PT--------VLTTTTTTVATGSMATPSSSTQTPGTPPPLTTTATTITATGSTI
TPSSTPGTTPIPPVLTS------TA-TTPTATSSKATSS--SSPRTATTLPVLT------
---------------------------STAT-----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------KSTATS--------------FTPIP-
---------------------------------SSTLWT--TWTVPAQ------------
------------------------------------------------------------
----------------------TTTPMSTR------------------------------
------------------------------------------------------------
--------------------------------STIHTSSTPETTHTSTV-----------
----------------------PTTTATMTR-----------------------------
----------------------------ATNSTATPSSTPGTTW----------------
--------------------------------------------------ILTELTTTAT
TTASTGSMATPSSTPGTTWILTEPTTTATVT-----------------------------
-------------------VPTGSMATASSTRATAGTPNVT---------TTATTPTVTS
SKATPSSSPGTAT-TLPALISTAT----TPTATSFTAI------PSSSLGTTWTRLS---
------------------------------------------------------------
-------------------QTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSV-
-------ATPSSTPGTAHTTKVLTTT---------TTG----FTATPSSSPGTAPTLPVW
ISTTTT-----------PTTSGSTVTP------SSIPGTT------HTPTVLTTT-TT--
----------------TVATGS-----MATPS--------------------SSTQTPGT
PPPLTTTATTITATGSTTTPSSTPGTTPIPPVSTTIATTQGQSLSTVTPSSALGTTHTPP
VPNTTATT-HGRSLSPSSPHTVPTAWTLATSGNSATLGTTHITEPSTVTSHTPAGTTGTT
PYWT----PAVSSPHPSSRTTESPPSPGKTTVGLTTATSRTTATPSKTSTSTLL-PSSPT
PAPTTPVV-TTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_55 (9139, 9227)

WSDWLDYSYP----MPGPSGGDFDTY----------------
--------------------SNIRAAGRAVCEQPLGLECRAQ----

ENSGT00760000118896_5_Linker_55_56 (9227, 9740)

AQPGVPCGIPTGHT
RSPLATIHPHWPHSVPTGHNPS----------S-LAI-LGP-HWPHSA---S-AL---ST
P-F---PGTAAPSCS-DLCLCSP-R----TLAYP--------------------------
------------------------------------------------------------
---------------------------------------------------SLGMAFLSM
VLFFTGEVIYN------KTD--------RAGCHFYAVCNQHCDIDRFQ-GACPTSPPPVS
SA----------PL----------------------------------------------
------------------------------------------SSPSPAPGCDNAIPLRQV
NETWTLENCTVARCVGDN-RVILLDPK--PVANVTCVNKHLPIKVLDPSQPCD-FHYECE
C-----------------I

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9836)

CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLY
LDNHYCAASA--A-AARCPRALSIHYKSMDIVLTV-TM-VHGKEECLILFDQIPVSSGFS
LLDLQVS-----------------------------------------------------
------------------------------------------------------------
-----------------------------------------------GP-----------
------------------------------------------------------------
--LLSSCRNQSPQ--------L-----EGLAEGCFCPEDQILFNAHMGICV-QA-C----
-PCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCEAQGQPPPCNRPGFVTVTRP
RADNPCCPETVCECNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRP--QL

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CSYNGT
------FYGVGATFPGA-LPCHMCTCLSGD---TQDPTVQCQEDACNNTTCPQGFEYKRV
AGQCCGECVQTACLTPDG------QPVQLN----QTWVNSRVDNCTVYLCEVEGGVHLLT
PQ--PASCPDV--S-----SCRGSLRKTGCCYSCE-E--D----------SCQVRVNTTV
LWHQGCET--EVNITFCEGSCPG-ASKYSAEAQAVQHQCTCCQERRVHEETVPLLCPNGS
AILHTYTHVDECGCTPFCVPAPMAPPHTRGFPAQ--------EATAV-------------
-----------

---GQGGPS------SGFSSTPTPPPAETQSPAEPSW----GSTG--------------G
LPSV----GGRGV-----GVDIGRP--VHA--LPAAWNPAHSGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSAHCGAAYEDFNVQLRRGLAGSKP-TITHIVLKAPGLVLEVSNGSVL
VDGQR---------EELPYSRAGLLVERSSEYVKVSVRLVLTLL-WN-GE---DSAL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 335)

AFNEF---------YAHNARLSPLQFGNLQKLDG
PTEQCPDAHPEP-------G-----------AGP

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CTRTLRGPAFAECNALVDASAYLAAC
AHDLCRC------P----TCPCATFAEYSRQCAHAGGQPQNWRSPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMEH
QECGSPCAD-----TCSNPQRSQLCEDHCVDGCFCPPG------------TVLDDVTHA-
---GCLPLGQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHSGRTYAPGDSFATSCSSCTCSGGLWECQARPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KKCADNTFAVLAELRQCGLTDNENCLRAVTLHLDGGDTV-I
RIQADGSVFMNSIY--TQLPVSAANITIFRPSSFFLVAQAGA-GLQLQVQLVP-LMQVFV
RLDPAYRGQTC-----GLCGNFNQNQADDFTALSGVVEGTGA-AFA------NTWKTQAA
CPNVRNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSWLT-NPAGAFSSCHSVVNPAPFHSNCMFDTCNCEKSEDCMCAALSSY
VRACAAKGVLLRGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCAKYMSS

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQSYAYVVDACPPSCRALSE-GDVTCGVSFV
PVDGCTCAEGTFLDDAGACVPARECPCYLHGSAVAPGEVVHDSGAVCSCVSGRLSCLGAA
PQTST---GCVAPMVYLDCSNTSAGAPGAE-CLRSCHSLD---VDC--FSTHCVSGCVCP
PGLVSDGAGGCVA-EEDCPCVHNEASYRPGDTIKVDCNT-------C----TCRNRRWEC
SRRPCLGT

PF00094 // ENSGT00760000118896_5_Domain_21 (1689, 1757)

CVAYGDGHFITFDGERYSFEGSCEYTLAQD--YCGGNT-THGTFRIVTENVP
CGTTGVTCSKAIKLFVE-----------------------------------VRAPARRE
PPPRA--KP-PGEQPPQEPPPQA-------------------------------------
------------PPPRVQPPQEPPPRPPPPGFGNSWKFSPNCPDAPAPKDPCTANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIINGATFAACRS--QVDSTKYYEACVSDACACDSGGDCECFCTAVAAYAQACR
DAGLCVSWR-TPDVCPLFCDYYNPHGECEWHYQPCGAPCLRTCRNPSGRCLVDLPSLE--
--GCYPKCPPSKP--FFSEDQMRCVA--WCGC---------YDEDERY------YDV-GS
RVPTAENCQSCN--------CTP-SGIRCTHSLE----ACTCTYEGRTYGYRDVIYNTTD
GLGGCLSAICGDNGTIIRRTVECPGTP----STTPPFTFTTI------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------STLSTVCVR----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSAWYDGVRPEPGEGGGDFETFASLRQKGYEVCSAPA---DIECRAEGLPHTPLQELG
QKVACDRTRGLTCVNSEQSP--P-LCLNYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCDYVP--CGPSPAPGTSPQP-----
----------------------------------------------------SPGTTA-E
PPRSPST-----------------------------------------------------
--------QTRVTEGTTPPAVP-------------------------SSPSTAA------
----------------------------------------------------LTSQTRPS
L---------PTVGPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTEWFDEDYPKSERAGGDIESYDKIRGAG-RDICE
RP---QDIQCQATNFPNWTLEQVGQ-R-VHCHVRFG-LVCWNEEQD--GMFKMCHN---Y
-KIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCS-TQHCRGHTSALPPATTPG--------------------------------
-----------------TATR---VPR-LWSSKPQPSSPEVTWTPPASTTAVP-------
-IPSKGPTS-P-----------SYSAPPSS-------------TPPTSPGWATSILPTR-
PSLTGTTGATGTWRPSQTPTPAPTAQ-TSTARLTG--TAS-T----VSKEPLTTGPVLT-
-------THTSQLPTSYTETSSLRSETP----PSTSAGGTTSQGTTGCQP-KC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDFPISGVAGGDIETLENIRA-AGGKMCGAP-E---KIECRAENYPEV-SIDQIGQVLI
-CSLETGLICRNEDQVGRFNMCFNYNVRVLCCDDYRHCPSTAAPSG-SSSPATTSLAATT
-----------------------------------------SLGTTFPSTTSLATR----
-------------------------------------------------S----------
---------------------------------------------------SL-------
--VTGLSTT-------------------------ATTSPR--------------------
------------------------------------------------------------
--------------------------------------------ITQRVVSTTQSGLTFS
VSSPSSQPASTTSP----------------------------------------------
------------------FHTTG---------------------------QPTSGT----
----------------LTT-----------------------------------------
------------------------------------------------------------
-----------------------------STRPPLT------------------------
-----------------------------------STPHTAPLLTSS-------------
--------------------------SGS-------TLGTTLPSSRPSTSKGCVPRCA

PF13330 // ENSGT00760000118896_5_Domain_37 (4199, 4292)

WT
DWFDEDYPIPGPDGGDFETYAVIRSAGYAFCEH-PQ---DIECRSEKEPDQPLEAVGQVV
QCDVRFGLVCRNRDQVGQFELCLNY-LIRVFCCN-YSD--CLSTPPTTTGSSP-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------GP--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------SP-----------------------
---------TSATT----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------L----A
P-----------------------------------------------------------
--------------------STT--------AL---------------------------
--------------------------------------SLPTH-----------------
------------------------------------------------------------
-----------------R--------PRTS------STASTVVPTSCQPACR

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WT------
DWLDSDRPQPGR-FGGDIETYYHIME-VGGQLCLEPA---AIECE-AVLFPDVSVGLLGQ
VVQCD-----------VRYGLICRNHRQKS-GQTCLNYHIRVRCCDY-------------
-----SH-CASTTSPLPTSTPMPTPHSTFSPAFSASTPSTL-WSSAGPRPSTVATTSLAT
ISSGTT------------------------------------------------------
--------------------------------------------------------STGT
TSTGTT--------------------STAN-------------T---SMGRTSIGTTSTG
TTSPGITSSATAYS----------------------------------------------
-----------------------------------AITSTG-------------------
--------------------------------------TPSPATTSTGTTST-ATT----
------------------------STGTTSTGTTSIGKTSTGTTYPXXXXXXXXXXXX--
-----X-XXX---XXXXXXXXXXXXSLAT--T----------------------------
----------SSGTTSTG-TTSTATTSTSTTSIGKTSTGT-------------TSP----
------------------------------------------------------------
----ATTSM--------------------------GTTSIGTT-SIGTTSPV--------
-----------TTFTGTTSIGTTSPATTSTGTTSIGTTTTGTTSSVTTSTGTTFIGTT--
------------STGTTPPATTSLGTTSTVT-----------------------------
----TSIASTSTGTTSTATISSGATSRGTTSSTTN--SPSTTSSGTTSSATTCPGTTST-
------------------------------------------------------------
------------------GSTSIATTSMGTTSMA-------------------------T
TSLGTTSPSATSLATR------LSLVTGPTTIATTSPRNTKMV------------NVSTT
SPSALPA---STTTPGT--SPQPSPGTTAEPPRSPSTQTRV-------------------
---------------------------TEGTTPP--------------------------
----------------------AVPSSPSTATRPSLPTVGPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

QWTEWFDEDY
PKSERAGGDIESYDKIRGAGRDICERP-Q---DIQCQATNFPNWTL---EQVGQRVHCHV
RFGLVCWNEEQDGMFKMCH---NYKIRVLCCRTTS-TATT-SLATT------SS------
----------------------------------------------G-------------
---TTSTGTTS-----TATTSTGTTSIGTTSTT-----------------------TP--
---------------------------------------------ATTSLGTTSTGITS-
----TG----------------TTSLVTT-------------------------------
---------------------------------------STATTSTGTTFTATTSTGTTS
I-----------------------------------------------------------
-----------G--------TTSTGTTSPVTTST----------G---------------
------------------------------------------------------------
-------TTSTGTT----------STATTSMGTTFIGTTS----------------TGTT
STATTSTGTTSIGT------------------------------------TSTRTTSP--
------------------------------------------------------------
-VTTS-------------------------------------------------------
------------------------------------------------------------
-------TGKTSMGTTSTGTTSPVTTS--------------------------TGTTST-
------------------------------------------------------------
-----GTTSTATTSTGTTSI----------------------------------------
---------------------------------GTTSTGTTTPATT--------------
-SLGT---TSTGIT----STGTTSPVTTSTGTTST-----GTTS----------------
--------------------------------------------------PVT-------
------------------------------------------------------------
-------------------TS-------------TGT-----------------------
-TSIGKTSTGTT----------------------------------------Y-------
-------PVTT----------------STGTTST--------------------------
------ATTST-----------------GTTYPVTTF------------------TGTT-
-------STA--------------------------------------------------
-----------------TTSTG--------------------------------------
------------------------------------------------------------
----------TTSTGTTSTGKTSTGTTSPV------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TTSTGTTYTATTS---------------------------------
----------TGTTSMGTSSIATT--STGTT---------SIGTTSTGTTSPATTSTGT-
------------------RSPV----------T------------TSTATTS-LT----T
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--TSSG------------T-----------------------------------------
------------------------------------------------------------
-----------------------------------------TSAGTTSPATTSTATTSTV
NESWTLENCTVARCEGDN-HVVLLPPK--PVANITCVNGQQPLKVWNQSRPCD-FHYECE
C-----------------S

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGGSHYLTFDGTSYSFLDNCTYVLVREIHPRHGNLSIL
LYSHYCAASASVS-AASCPRALSIYYEHMEIVLTT-TT-VHGKEESLILFDHMRVSRGFT
KHGVSVSLTGASTMGIDIPAIGVSITFDGHSFQVRLSYSHFSNNTEGQCGTCTNNQKDDC
RQPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TTAPTCKDMAKSWLVPD----GSLEGCWAPTGPPPTASPTPQA------------
--PSTP---TPTLCPSE-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CE--LL-------LSQVFAECHGLVPPGPFFNSCISDGCH
TS---HPRVPCQSLEAYAALCRTHGVCSDWRNATGGLCDLT--CPPAQVY----KPCGPV
QPASCNSRNQSPL--------S-----GGLAEGCFCPEGQILFDSLKDICL-RP-P----
-SCVGPAGLPKLPGERWVSQCQDCVCDEGSVSVQCEPQRCEPQAQPPKCDEEGWVAVTRP
RADKPCCPETLCVCNATTCPPQSPPTCGPGQVLTRTQEEGKCCPTFLCRP--KLCTYNGT
------VYGVGAIFPGV-VPCLTCTCLSAD---PQDPTVQCEEAACN-TTCPQGFVYVSV
AGQCCGKCEQYACLTPHG------QPVQPN----GTWVNSRVDNCTEYYCEVENGQHMLI
PR--PSPCPDM--F-----SCRGTLRRTGCCYSCE-EV-D----------SCQVHVNTTV
LWNGDCATEGAVNVTFCEGSCPG-VSKYSVEAQAMEHQCACCQERRVHAETVSMRCPDGT
AILHTYTHVDECGCEPSCVPLPMVSTDG--------------------------------
-----------

----MGSRSWSWALVWASVALLMVWPAESQGQ-AELS----SEHP--------------E
LTGDSQKVYSAPTSTPTRHVTFIPPITAFP--SMSALHLAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSSHCGATYEDFNIQLRRGLEGSRP-TVTYVLLRAQGLVIELSHGSVL
VNGHR---------EKLPYSRAGLLMEKSSGYVKISIRLVLTFL-WN-EE---DSAL---
----LELDSKYTNQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 335)

AVSEF---------YTHNTRLTPVQFGNLQKLDG
PTEQCQDVLPSA-VSNCTDS-----------EDI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CRHTLLGPAFDKCTALVDVSMYLDAC
VQDLCRC------P----TCPCATFAEYSRQCAHAGGYPQNWRRPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CN--WT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMEY
QECSSPCVD-----TCSNPQRSQLCEDHCMDGCFCPPG------------TVLDDVRHL-
---GCLPLEQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTHGGHIYAPGESFNTSCRSCTCFGGLWKCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGSHIF
TFDEKLYNVHGDCSYILT-KKCADSGFTVLVDLRKCGVTDTENCLKAVTLNLNSGDMV-I
QIQANGAVFLNSIF--TQMPLSAGNITISKPSSFFIIVQAGM-GLQLQVQLVP-LMQVFV
RLDRSYQGQMC-----GLCGNFNQNQADDFTALSGVVEGTGA-AFS------NTWKTQAS
CPNSKNTYEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSYS
VE-NENFARE

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1459)

WCSMLT-ESSGVFSACHATVSPVPFYSNCLFDTCNCENSEDCMCAALSSY
VFACAAKGVLLSGWRD-K

ENSGT00760000118896_5_Linker_14_15 (1459, 1467)

VCYKYTNN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPQTKGYSYSVSSCQPTCRSLSE-ADVTCSIPFV
TVDGCTCPEGTFLNDKDHCVPVEE

ENSGT00760000118896_5_Linker_15_17 (1525, 1570)

CPCYFHGTVVAPGEVVTDNGVVCSCTNGRLTCLGAL
MQKST---E

PF01826 // ENSGT00760000118896_5_Domain_17 (1570, 1638)

CQAPMVYLDCNNASVGHHGAE-CLKSCHTLD---VEC--FSTQCVSGCVCP
SGLVADGNGGCVA-EEDCPCVHNEVTYRPGESIRVDCNN-------C----TCKNRRWEC
TNQPCMGA

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CVAYGDGHFVTFDGERYIFEGSCEYTLAQD--YCRGNTSTDGTFRIITENVP
CGTTGTTCSKTIKIFVE-----------------------------------NYELILHE
GNFKVVEQG-PSGDSPYKIRFMGIFLVIEIRSGIVVSWDRKTSVFVRLQQHYKGKVCGLC
GNFDDNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVGDV-------LEFGNSWKFSPSCPDAPVPKDPCIANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

KCSIINSATFAACHS--QVDSTKYYEACVHDVCACDSGGDCECFCTAVAAYAQACR
DVGVCLSWR-TPDICPLFCDYYNPHGECEWHYQPCGAPCLKTCRNPAGHCLVDLPGLE--
--GCYPQCPPSQP--FFSEDQMKCVA--QCGC---------YDDDGNY------HDI-GT
QVPKTENCQSCL--------CTP-GGLQCVYNLT----ACTCTYEGRTYNYNDVVYNTTD
GLGACLVAICKDNGTIARTTEVCHEVP----STT-PFTFTTT--LAPLAT----------
------------------------------------------------------------
-----------------------------NGS----------------------------
------------------------------------------------------------
----------APTVSTVCVH----------------------------------------
----------------------------------------------------------EV
C

PF13330 // ENSGT00760000118896_5_Domain_28 (2522, 2615)

HWSIWYDESHPEAGMSGGDFETFENLRKKGHQVCQTPL---GIECRAVKFPSMDLENLG
QKVNCDPSSGLSCFNSEQSP--P-LCHDYEMRVLCCDYVP--CGSSLTLGVSTTP-----
----------------------------------------------------SQPGTSRR
PSSSTLTTHTASSE---SQPWTREEKKTSVDKTQSSRQTVPFTSNSRPTSPPLSSRNSAS
SLPLSSPTWTTRLKATNENTML-------------------------SSRTTTA------
----------------------------------------------------FTSQTRSS
SRPSTVTQTVSSPETSSTT-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------CQP------------
------------------------------------------------------------
--------------------------------------------R-----WSAP------
----------------------------------------------MTGSATTASQ----
----------------TLSSMPHPNTT---------------------------------
-------------------------------------------------LSMTSP-----
-------HSASTTV--ATS-----------------------------------------
----------------------------------------------ISSVTETSSPRSVS
SSH----------------------------------STPKN------------------
----LPETLQS----------T-TGLTTQQ------------------------------
---------TSSTGIWTSILTGTAGTVS--------------------------------
---------------------------STSLSTS-LES-------------TTG------
-----------------------------------------------------------I
TEVSTSIPMTPTLPVTVTSATTPQGTTHCPPKC

PF13330 // ENSGT00760000118896_5_Domain_53 (7954, 8050)

KWTEWFDVDSPTSG---AVKGDMETYE
NIRASGKKICQAPE----KIECRAENYPAVSIDKVGQVVSCNLETGLVCKNEDQKDDFKM
CFNYNIRVL

ENSGT00760000118896_5_Linker_53_54 (8050, 8718)

CCDDYSHCPTTPYSTIK----------------------------------
------------------------------------------------------SPLVP-
FTT---------------------------------------------------------
------------------------------------------------------------
-----------------------------SV-----------------------------
----------------------------SLS-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TES--------------------------------------------------
-------------------------TFLTNRPASSSGP---------STQASTW------
-----STLPDSGCAPRC

PF13330 // ENSGT00760000118896_5_Domain_54 (8718, 8941)

KWTE-----WFDADFPN---------------------PGPR-
-------GGDFEVYAVFREVGYIFCDQP----KDIQCR----SEKEPDRPLETLEQ----
-------VVQ------CDVRFGLICKN------INQSGPL------QYCDN---------
------------------------------------------------------YHVRLL
CCDNYSHCTTSPMATMSTAPFSSHLPS----THT------------------------AL
ALNTT-------------------------------------------------------
----------------------------------------------------T-------
------------------------------------------------------FPPG--
----------------LSSSSEPHSSSLMSTHTST-MLTTETSPIATGPTVAPSSTSGT-
-----------------PHAPK----------V-SPS-S-QVTFSVSTASSS-VF---ST
PR----TVFSSHTSLSSTCFCQA-F----GQL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--FLPGDIIYN------KTD--------GAGCQFYAICNQYCDVDRFQ-GTCPSSSPPMS
ST----------PA----------------------------------------------
------------------------------------------SLPPLLPGCDNAIPPRQV
NESWTLENCTVARCQGNN-QIILLEPE--PVDNVTCANKHLPIKVWDQ-EPCH-FHYECE
C-----------------F

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGHSHYLTFDGTSYTFLDNCTSVLMREIHPRHGNLSIL
AHSYYCGATT--N-VTSCPRALSVYYNSMEIILTI-TTNDGGKEESLIIWDQMWLRSGFS
KNGVTVSLSGATTMSVNISTIGTSITFDGNIFQIWLPYRYFSSNTEGQCGTCTNSQTDDC
RRPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TIASDCRDMAKEWLVPG----NSSSSCLAQPSPPPSTTPQTPV------------
--SSTL---TSTPCPSA-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CE--LM-------LSQVFAECHRLIPPDAFFRSCVSDHCN
AN---ITDTLCQSLEAYAALCRAQDVCTNWRNATGGLCDLS--CPPTKEY----RPCGPL
HPASCNSWTQEPS--------N-----GMLAEGCFCPENQLLFNSRMDICV-SE-C----
-PCVGPDGLPKFPGEHWISNCQACVCDPGSVSVQCEPVKCESQDEPPQCTEAGFVTVTWP
SADNPCCSETLCVCNSTTCP-KSLPTCEPGYELVQTHENSSCCPSYSCRP--KL

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CIYNDT
------IYGVGTTFPG--GPCQTCTCLSDG---DQEPKVECMETNCS-TSCPQGFKYTLV
PGQCCGQCVQSACLTPEG------HVVQPN----ETWVNSPVDNCTAYRCMAENGVHVLT
PI--PTSCPDV--S-----NCMGTLRKTGCCYSCEKEDSS----------TCQVHVNATI
LRHKGCETE--VNITFCEGSCSG-ISKYSMEAQAMERQCTCCQESKVHDVAVTLQCSDGT
VIQHTYTHIDECNCAPACSSLPGTSMIAS-------------------------------
-----------

-----MTGIKDGRRLWILCILCS--CCHS-------------------------------
-----------------------------KTLIQKVQHPADTFSE

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 281)

CST-WGSFHFQTFDH
VKFNFPGLCHYVFASHCKDDYQDFNIEIMRSIKNGTV---IYCTATIDGVLLKLKESSIT
VDGNV---------ISLPFSLKSVVIEDLYPYIQVSSTLGLTLK-WN-WG---DTLL---
----LNLEDTYKGKTCGLCGNYDGNEKNDL----------

ENSGT00760000118896_5_Linker_0_4 (281, 329)

ILRGYKLSPWQFGNLQKVDD
PTKKCPDILGDSRKQ--KDNSRQQDKCK

PF08742 // ENSGT00760000118896_5_Domain_4 (329, 408)

SRYKSKCKRAL--SRFGNCAKVISLDDYLSLC
IEDMCDCSQKSSHSDLVASCVCSTFSQYSRDCVLQGGDPGKWRSKEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CY--QK

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPHNLEY
MECGNPCFD-----TCFNPERSKICRAQCTDGCFCPE---G---------KILDDIRDK-
---KCIPAAN

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTYQGKNYSIGDTYSLPCQNCTCTDGKWSCLSLPCSGH

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CKIEGGFHIT
TFDKKQFIFHGNCHYVLA-K-DTDGSFVIIGEIVQCGLSNTMTCLKNVLITVGA--I-KI
RICSCGDVYVNNVI--ATLPLTKDGVILFRPSTFYVNIVTSS-RVQIQVQLKP-IMQLFI
TVDETYQNRS-----SGLCGNFNNIQADDFQTISGIIEDSAS-AFG------NSWKTMAN
CADVQDSSEDPC------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------WKS
VG-KEK

PF08742 // ENSGT00760000118896_5_Domain_14 (1387, 1460)

FGQHWCAVLL-NTSGVFAECHSVSDPTPYAKNCAYDTCNAENSKEVLCSVFSAY
ARDCASRGIHLKGWRN-GI

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CDVS-TE

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPRTMEYSYEVKFCNRSCRSLRE-PDLLCNVHVV
PVEGCGCPDGTYLMNENECVSPED

ENSGT00760000118896_5_Linker_15_17 (1525, 1588)

CPCYYKGQMIQPGNLLRKDGLMCKCIQGQLDCIGKA
EI-RK---ECPFPMYYFDCDSAGPGAT

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GSE-CQKSCKTQD---MQC--YATECVSGCVCP
NGLLTNSNGGCIE-EDQCPCIHGGNYYSPGTYITVNCNT-------C----LCQKRQWNC
TENPCQGI

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1874)

CTVYGNGHYVNFDGTKFDFMGDCDYILAQD--FCP-NNLQPGTFRIIVQNTA
CGKSLSVCSLKITIFLE-----------------------------------GSEIRLME
DKIKEITSK-PDTQKGYTIYIMGMYITIRTSSGMTFIWDQKTTLIVQVAPSFQGRVCGLC
GDFDNSANNDFTT

ENSGT00760000118896_5_Linker_20_26 (1874, 1923)

RGQSVEIDS-------QTFGNSWKVTSSCSDM-NKRDLCVKQPSKLA
LG

PF08742 // ENSGT00760000118896_5_Domain_26 (1923, 1996)

RKYCSIIKSETFGACRS--KINPTPYYETCVSDFCGCDNVPNCECFCTAVAAYSKSCG
RAGICIDWR-SPRNCPLFCDYYNPPNKKEWHYKPCGEPCLKTCRNPAGKCDDLLYSLE--
--GCYPECSAEKP--YYDEEKRECVSMLECTS---------CDP----------------
------------------------KETLCLNKSN----GKMSKWQIYISCIGEIF-RVY-
-----VSSVCDENSSF---CISCGMK----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------I------
----------------------------------------------------------VS
SV----------------------------------------------------------
-P---------------------------------------------------------Y
-EF---------------------QIGIVL------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------GK-------------------------LAM
-----------------------------------------------SS-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----T-------------------------------------------------------
------------------------------------------------------------
----------------------------------------I-------------------
------------------------------------------------------------
------SPAKQ-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------EIRIS------PC---------------------
------------------------------FCNI--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------N----------------------------------------------
-------------------------------------R---Q------------------
------------------------------------------------------------
-------L----------------------------------------------------
------------------------------------------------------------
----------------------------------------------IT------S-----
------------------------------------------------------G-----
------------------------------------------------------------
------------------------------------------------------------
---SSQFL----------------------------------------------------
------------------------------------------------------------
-TR---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------DA----------------S---------------------GWCIYA------
-------------------------------FC-------NATCQ---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------TEF----------
------------------------------------------------------------
-------------NFGECIS-------------------F--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------STTT------------I-------P-----------------
------------------------------------------------------------
------------------------------------------------SKLPLI------
------------------------------------------------------------
------------------------------------------------------------
------------------------------P-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------NRPCKENI----------------------------------------------
--------------EKCEKQPP--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PY------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------S---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------A-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------GNIV----------------------------------------------
------------------------------------------PTFTPGSDCTNLHPPRKF
QEIWTFGRCHIATCLGDK-NIKISDVQCPPPKLKLCVNGLPLVKSRDA-SGCC-GNSECQ
C-----------------A

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9891)

CSGWGNQHYLTFDGSYYNFRGNCTYLLMKPFRPGSQNFWIQ
LDNHYCAAS---E-RAVCSLTLFIFYNHSIIILTR-GV-ENGKEGNLVLYNNKKITPGFS
SDGFDITISG-QYVVVKIPEIGLYITYTHLIFYINLPFSTFYNNTEGQCG

ENSGT00760000118896_5_Linker_56_57 (9891, 9978)

KHRRNC----
-----ECT--------KWVLIILTVCLYRRNCVCGVESQ-HLQ-----------------
--PSQA---EMAACTGP

PF08742 // ENSGT00760000118896_5_Domain_57 (9978, 10054)

-PLCK--LI---------WNLTECHNVVPPWPYYDACVIDGCS
A---KKQNTECRSLQAYAALCGFHGICVDWRSKTSRKCELT--CSGGQIY----NPCGRM
ERITCPSGKNTSSANL-----LQNEIPGIFVEGCFCPDGLIQLKYHDNICV-SLC-----
-GCKGPDGVVRQPGESWEKDCQVCTCSKETLEISCTSHICARFP-PISCTAEGFVPVVRI
QSEDPCCTETVCECDINSCA-PIKPECNPGFQIATVTSQDACCPIYFCRP-KNVCVYQGI
------EYQPGFLVPSD--SCEECICTETQDPKTKTNQIKCLPMKCS-TECQKGFHYIQE
EGKCCGECVQTECVAELSFG---TVSIGVG----QSYKDP-HDNCTQYLCTKLSDQFILS
ST--VKACQILDQSNCV--PGTTQTTPDGCCETCI-L--LS--------HNCKITQKKQY
IYHDQCKSITPIMIPSCEGFCDT-YSVYSFVTHKMKHRCTCCQATKYHGVRVELICSKKK
RMKYTYLHVDECGCMETKCSA---------------------------------------
-----------

----MGVGQRKLAPLWTLALALA--CTRHTGHAQDGS----SESSYE------HHP---A
LSPIAQGPGGV----PPRGVTLFPPLRTIP--VVRASNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSEHCGAAYEDFNVQLRRSQESAAP-TLSRVLMKVDGVVIQLTNGSVL
VNG---------RPVLLPFSQSGVFIQQSSSYTKVEARLGLVLM-WN-HD---DSLL---
----LELDAKYANKTCGLCGDFNGM

ENSGT00760000118896_5_Linker_0_4 (266, 335)

PVVSE-L--------LSHNIKLTPMEFGNLQKMDD
PTEQCEDPVPEP-PRNCS--T---------GSGI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEELLNGQLFSSCVALVDVGSYLEAC
RQDLCFCGGT---D--LLSCVCHTLAEYSRQCAHAGGLPQDWRGPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPSNMQY
HECRSPCTD-----TCSNQEHSRACEDHCVAGCFCPE---G---------TVLDDVGQT-
---GCVPASQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACVYNGTAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGAHFS
TFDERHYTVHGDCGYVLT-KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV-V
VIKASGEVFLNQIY--TQLPISAANVTIFRPSTFFIIAQTNL-GLQLDLQLVP-TMQLFV
RLAPKLRGQTC-----GLCGNFNSIQADDFRTLSGVVEATAA-AFF------NTFKTQAA
CPNIRNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1458)

WCSQLT-DANGPFSRCHAAVKPDTYYSNCMFDTCNCERSEDCLCAVLSSY
VHACAAKGVQLSGWRN-

ENSGT00760000118896_5_Linker_14_15 (1458, 1467)

GVCTKPMTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYHYNVSTCQPTCRSLSE-GDITCSVGFI
PVDGCICPEGTFLDDTGKCVQASN

ENSGT00760000118896_5_Linker_15_17 (1525, 1586)

CPCYHRGSVIPNGESVHDSGAVCTCIHGKLSCIGGQ
AP-TP---VCAAPMVFFDCHNATPG

PF01826 // ENSGT00760000118896_5_Domain_17 (1586, 1638)

DTGAG-CQKSCHTLD---MTC--YSPQCVPGCVCP
DGLVADGEGNCIT-VEDCPCVHNEASYRAGQTIRVGCNT-------C----TCDSRMWRC
TDDPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CAVYGDGHYLTFDGQSYSFNGDCQYMLVQN--HCGRKGSAQDSFRVVTENVP
CGTTGTTCSKAIKIFLG-----------------------------------GSELKLSH
GKVEVTGTN-ESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKSRVCGLC
GNFDDIAVNDFATRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVGDV-------LEFGNSWKLSPSCPDALAAKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACHA--HVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACH
EAGLCVSWR-TPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLQDVRGLE--
--GCYPKCPPEAP--IFDEDKMQCVA--TCPT---PPPPPLCHVHGKS------YRP-GA
VVPSDKNCHSCL--------CTE-RGVECIYEAE----ACVCTYDGQRFHPGDVIYHTTD
GTGGCISARCGANGTIERRVYPCSPTTPV--P---PTTFSFS--TPPLVVSSTHASSPVP
----SSMHT------------------------------------------GSPSSAWP-
------TTAGT-----------SPRT--RPPT----------------------------
------------------------------------------------------------
----------ASASLPPVCG----------------------------------------
----------------------------------------------------------EE
CL

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWMDVSRPGRGMDSGDFDTLKNLRAHGYLVCESPR---SVECRAEDAPQVPLRALG
QRVQCSPDMGLTCRNREQAS--G-LCYNYQIRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCTPLA--CSTSSSSTQTTPPTTSKT
TET--------------RAS--A--SSVPS------------------------------
----------STPG----------------------------------------------
-----------PVSLSTSRAT--------------------------PAPGTAT------
---------SVK--RT--FSTPSPPP--VP----ATSTSS----V-------STTAPGTS
VVS---SKPSHTESITPSCVHELC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

TWTEWIDGSYPDPGINGGDFDTFQNLRDEG-YKFCE
NP---QSVECRAVGFPNTPLADLGQ-D-VICSRTEG-LICLNKNQL----PPICYN---Y
-EIRIQ

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCKTVNKCRDGTRTLKTITTTRPT---PHPAGAQ--------------------
------------------TQTTFTTHVPSASTEQ--------------------------
------------------------------------------------------------
-------------------------P-----------TAT------SR------------
-----------------------GGSTA----TSVTQDTHNRSVTRDCHP-QC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

TWT-KWF
DVDFPSPGPHGGDEETYNNIIR-SGEKICRQP-EEITRLQCRAASHPEV-SIEHLGQVVQ
-CSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPKGCPVMSTPVTAPSTPSGRAT----
---SPTQST---------------------------SSWQK-PR----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TTTLVTISTTSTPQTSTIS---------------TPTTNMT
SA-----------------PTPRTT-----------------------------------
------------------------------------------------------------
-------------------------------------------------------SAPTT
S--TTAAPTTS-T--------------S--------SAPT--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------TSTTSAPTTNTTSAPTPRTTSAPTKSTTCTRKTSTTSAPTTSKTSAS
TTIPTT------------------------------------------------------
------------------------------------------------------------
-----------SKT-----------------------SA---------PTTST-------
-SSAPTTSTSST------------------------------------------------
-----------------------------------PTTSTTSIPGTTASPVPTISTTSAP
TTRTTSAPTSS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------TTSAAITST
TSAS--------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------TTIPTTR
TTSAP-RTSTSSPPTTSTSSAPTTSRTSIPRSTPSPVPTTTT----SA-PTS--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------ST-----TSTAMTSTTSGPE---TTPSPV-
P----------------TFSKTSASTTST------------------------T------
------------------------------------------------------------
---------SGST--T--------------------------------------------
-------------------------------------SGPATIPSPVSTTSTTTAPT---
TRTT-----------SALT-------------S---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------STTSGP--
----ETIPKGCPVTA-VTPYGTS-TN-TLYPSL---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------STSV--------
-----------------AS--------------------------TSVASSS-VAS----
-SS---VASSSVAYSTPTCFCNV-T----DRL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--YPMGSTIYR------HRD--------LAGHCYYALCSQDCQVVRGVGSDCPSTTLPPA
PAT--SPWT---ST----------------------------------------------
------------------------------------------SEPVTELGCPNAVPPRKK
GETWATPNCSEATCEGNN-IISLRPRTCPRVEKPTCANGYPALKVADQ-DGCC-YHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVL
VDNDFCGAE---D-GLSCPKSIILEFQQDRVVLTR-KS-VHGAMTNEIIFNNKVVSPGFR
KNGIVVSRVG-IKMYATIPALGVQVMFSGLIFSVEVPFSKFANNTEGQCGTCTNDLKDEC
RTPGG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TVVASCSEMSGLWNVSI----PNQPACHGPRPLPTTVGPTTV----------GST
TFGPTT---PPAPCPPS-SI

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CR--LI-------LSKVFEPCHAVIPPLPFYEGCTFDQCH
KT---DLDTVCSSLELYAALCASQDICIDWRGRTNHMCPFT--CPADKVY----QPCGPS
NPSYCYGNDSASL--------GALPEAGPITEGCFCPEGMTFFSTSAQVCV-PTGCPTAV
D--AGPQASPSQVGHTVGRDCQECTCEAATWTLSCRPKLCPLPP---ACPLPGFVPVPAA
PQAGQCCPQYNCACNTSHCP-A-PVDCPEGARAIPTYEEGDCCPVQKCNW--TE

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CSING-
-----TLYQPGAVVS-S-SLCETCRCELPGGPLSDTFVVSCETQICN-SHCPVGFEYQEQ
SGQCCGTCVQVACVTNTSGS--STHLFYPGMHLAETWSDP-GNHCVTYECEKHLDGLVVV
TT--KKACPPLSCS-----LDEARMSKDGCCRFCP-P--TPLPPQYQNQSTCAVYHRSQI
IQQQGCNSSEPVRLAYCRGNCGDSSSMYSFEGNMVEHRCQCCQELQTSLRNVTLHCADGS
SRTFSFTEVEQCGCRGQRCPTPGDTQHSEEMGPE--------QSQEAGSGSWERGTLVSP
VH---------

-FQKMGTGSGTRIPLWISILALAFTQIKVQVQGEEQQ----SQSNYDSLSFLQRKN----
---------SLSLGTKSHGLTIIPPLQNTL--NVKAGNPSHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 285)

CST-WGNFHFKNFDG
DIFYFPGVCNYIFASNCKSSYEDFNIQIRRTMVENAT-MITHVIMKLEGAVVELTRTSVL
VNGQQ---------VQMPYNHMGVLVERSNSYLKVSAKLGLTFL-WN-EE---DALL---
----VELDKKYANQTCGLCGDFNGIPTNNEF---------ISQN

ENSGT00760000118896_5_Linker_0_4 (285, 318)

TKLTAVQFGNRQKIDG
PTEQCDDPIPPAVLKNC

PF08742 // ENSGT00760000118896_5_Domain_4 (318, 409)

SSEF----------ASICKTVLTSEAFTSCNVLVDVQDYIETC
IQDLCHCDTS---M--ADFCMCNTFAEYSRQCAHAGGQPLNWRTSELC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--KS

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMQH
QECGSPCSD-----TCSNPERSALCEDHCTDGCVCPP---G---------MVFDDINGA-
---GCIPRKE

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTYEGETYAPGTSFSSKCRSCTCAEGEWACVTQSCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CSIEGGSHIS
TFDEKYYSFFGDCSYVLT-KLCDSNDFTVLGDIHKCGLTDTETCLKGVTISLSGGQT-NI
VIQPSGSVFVNMIY--TQLPFSAANVTIFRPSSFFIILQTTF-GLQLQIQLTP-IMQLFI
NLDPSHKGQTC-----GLCGNFNDVQTDDFKTTSGVIEGTSA-AFG------NTWKTQAD
CPDAKITFENP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CTLS
IE-N

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1461)

DKYAQHWCGLLS-DTMGPFAECHSTVNPEVYQKNCMFDTCNCENTEDCMCAALSSY
VRACAVKGVLLNGWRN-KVCTKYTNTCPKSLKYTYNVDSCQPTCRSLSE-PDVTCNIKFV
PVDGCTCINGTYMDESGKCVPASSCPCYYKGMPLSPGEVIHDNGVVCTCTYGKLSCIGEK
P---Q--PVCASPMVYVDCGNATAGVAGAE-CQKSCQTLD---MEC--YKTHCVSGCICP
HNYVLDGKGGCIA-PEECPCVHNGDSYSPGESIRVGCNN-------C----TCRNRKWHC
SEEPCLET

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1877)

CSVYGDGHYTTFDGKRFDFEGDCEYVLIQN--YCGKKGLDQGTFRVITENIP
CGTTGTTCSKSIKVFLG-----------------------------------NYELVLSD
GRSDVIQRTPG-GEMPFQIRSMGIYLVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLC
GNYDGNGNNDFTTRSQ

ENSGT00760000118896_5_Linker_20_26 (1877, 1919)

SVVGNV-------LEFANSWKVSSTCPNANQTKDPCTANPYR

PF08742 // ENSGT00760000118896_5_Domain_26 (1919, 1996)

KS
WAQKQCSIITSEVFAKCHS--QVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACN
ELDICISWR-TPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLE--
--GCYPHCPKNKP--YFDEETMTCVS--NCGCY------EN----GKH------YKP-GT
QMPSKQNCQSCE--------CTN-HGKKCKYDEH----ECVCTYEGQTYNYNDVIYNTTD
GIGGCIVAICGPNGTLQRVVYHCP-VSASP-T---PFQFSTT--PPATTSTG--TYF--I
ATESLFYSLV---------------------------------INYQMITLSR-------
-------IPDYRTK-WTTQIMALSLS---VT-----------------------------
------------------------------------------------------------
----------SSPTTSVCVHE---------------------------------------
-----------------------------------------------------------V
CQWSEWYDGNLLIPGYDGGDFETFDDLRAKGYEVCRAPK---AVQCRAEKFPNIPLKDLG
QTVECSTTSGLICYNKDQIS--T-MCYNYEIRILCCVFV--PCSSTPFITT--PYETST-
PIT------------HIPVPE---------MTTTTASTS-VTTSATSTE---KTSPII-E
TSTPSETPLE--TS----------------------------------------------
-----------TS------TTPITS-------TMPC----QPKCK----WSQCTPSTVPT
T-------------SE--TSTFTPS--------VTKEIT----------TTT-----TKT
MKPVTT-----IPSTTPGCIKEECDWSIWYDVSYPESGYNDGDFDTIENIIKHG-YKVCA
NR---KAVECRAVRFPDTPYQLLEQ-R-ITCNAEEG-LICYNKDQL--P--PICYN---Y
-EIRFKCCRNITVPCETT-QTTTQE--------ST-----TMTYST-T-------QS---
---TQYT------KISTTE---------------------QT-----PEFHTK-------
-HKTT-T-----------------------------------------------------
---------------------------------------A------STIPPKTEHI----
---------H-------SETTSTPTT---------------QTQT-------ESKT-TYT
TLPTPVTT----------------------ST----STVPISSESTP-------------
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-----------

----MAVGRRKLAPLWALAFALA-------------------------------------
--CTRG-VPGD----PLLRMTDTPPLSTIP--VVQAPNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGDSHYKTFDG
DIFRFPGLCNYVFSAHCGAAYEDFNVQLRRSRAANTT-TLSRVIMKLDGLVIELNESSVL
VNG---------HPVQLPFSQSGVLMERSNGNLKVTARLGLVFM-WDQDD---DSLL---
----LELDSKFANQTCGLCGDFNGI

ENSGT00760000118896_5_Linker_0_4 (266, 335)

PVFNEF---------LSHDVRLTPMEFGNLQKMDG
PTEQCQDPDPAP-Q-NCS-IS---------S-GI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEELLRGQLFSGCAALVDVSSYVEAC
RQDLCLCEQA---D--LPSCICHTLAEYSRQCAHAGGLPQDWRGPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CY--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCTD-----TCSNPQRSQLCEDHCVAGCFCPE---G---------TVFDDIGQT-
---GCVPMSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCMYNGTSYAPGANYSTDCTRCTCSGGRWSCQEVPCQGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGSHLS
TFDEKQYTVHGDCSYVLT-KPCHDDAFTVLAELRRCGLTESETCLKGVELRLGGGPTA-V
VVKASGEVFVNQIY--TQLPVSTANVTLFRPSTFFIIAQTHL-GVQLAIQLVP-TMQVFV
RLAPELRGLTC-----GLCGNFNSIQADDFRTNSGVVEGTGA-AFA------NTWKTQAA
CPNAKSSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSQLT-SPDGPFAQCHATVSPSTYYSNCMFDTCNCEKSEDCMCAALSSY
VQACAAKGVLLRGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

A-GVCTKPTTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYHYHISTCQPTCRALSE-EDVTCHVSFV
PVDGCACPEGMFLDASDKCVPAASCPCYHRGSMVPNGESLHDSGAVCTCTQGTLTCIGGP
AT-PD--------------------DAGPGSCPHHSLCPC---ALQ--YSPQCEPGCVCP
PGLVADGSGGCIA-AEDCPCMHNGASYRPGETIWAGCNT-------C----TCENRMWRC
TEEPCQAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CALYGDGHFLTFDGQRYTFSGDCQYTLVQD--HCGGNGSAKDAFRVVTENVP
CGTTGTTCSKDIKIFLG-----------------------------------SYELKLSS
GKVEVVQKG-AGQEPPYTIRQMGIYLVVDTDAGLVLLWDRRTSIFLRLSPEFKGRVCGLC
GNFDGNALNDFTTR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SQAVVGDA-------LEFGNSWKLSPSCPDALVPKDPCTTNPYRKA
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIIHSATFATCHA--HVEPTMYYEACVGDACACDSGGDCECFCTAVAAYAQACH
EAGVCVSWR-TPDVCPLFCDYYNPQGECEWHFQPCGAPCMRTCRNPSGRCLHDLRGLE--
--GCYPKCPPSAP--IFDEDKMQCVD--KCPT---PTPPPPCRIHGKS------YRP-GA
TVPSDKNCYSCI--------CTE-NGVHCAYDSG----ACVCTYDGRHFHPGDVIYNTTD
GMGSCISAHCGANGTVERRVFTCSPSTPR--P---PTTFSFS--TSPHTF---------S
LRQTTGVGSS--------------PT---------------QSTVH----PVPVSTAS--
------STATGT----------PLRT--TPAT----------------------------
------------------------------------------------------------
----------PPVSSSVHCG----------------------------------------
----------------------------------------------------------EK
CL

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWLDVSRPGQGVDSGDFDTLQNLRAHGFRICQVPR---AVQCRAEDAPEVPLQALG
QRLECSPTAGLTCHNRDQAS--G-LCHNYQIRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCSPLP--CPTSSPPARHRTTNT---
--------------------------VPMTSAT-----------------VS-S--TP-V
RT--SFLKSSPTPK----------------------------------------------
-----------TTSGTPSASA-----------------------------SPPGR-----
-----------------------------------SQV----------------TSVP--
---------TTSGVSPVSCLRESC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

TWTQWMDGSYPGPGKDSGDFDTFHNLRSKG-YKFCE
RP---TSVECRAQFFPNTPLAELGQ-Q-VTCNSEEG-LICWNRDQL----PPICYN---Y
-EIRIQCCELVDDWTPKSIATHP-KSTEGS------------------------------
-------------T---TTKTTVTTGS---------------------------------
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----------------------------QAT-S---------------------------
------------------------------------------------------------
---------------------TG--------H---------------------TTHP---
------------------------------------------------------------
--------------------------------------------TPVHTSR---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------GT-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------SVGTKVTQSQTTDCQPQC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7272)

TWTKWFDVDF
PDPGPHGGDTETYSNILSKGERICLQP-EDITRLECRE----------------------
----------QQGPLGMCL---NYEVRVLCCHTPDGCPTTGT-PAWTTPPEPSS------
------------------------------------------------------------
------------------SV----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------P--
STSAVSSPW-SPSSA-------------AS------ST--------LP------------
------------------------------------------------------------
------------------------------------------------------------
-------CFCSVLD----Q------------LYPAGSI----------------------
------------------------------------------------------------
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-----------------------------IY-----------------------------
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----------R------QRD--------LSGHCYYALCSQDCEVIKGVDHDCPSTTPPPT
SVS--SLSM---ST----------------------------------------------
----------------------------------------------PETGCPNMHPPREK
GETWPMPNCTQATCEGNS-IISLRPRQCPEVKEPTCANGYPALKVADQD-GCC-QHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQVVPVFGHFRVL
INNDFCDPK---D-QLSCPQAIIVEYHQDRVVLTRT-P-VGGVMTNQIIFNNKVVSPGFQ
SNGIAVSRVGIK-MYVTIREIGVQVMFSGLIFSVEVPFSTFANNTEGQCGTCTNDKRDEC
RLPGG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TVAPSCSAMSGHWKVDV----PGQPHCHGPPPTPPSTTP----------------
----QT---TPVQCPPS-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CE--LI-------LSKVFQPCHHVISPQSFYEGCVFDYCH
MT---PPDVVCSGLQLYAALCASEGVCIDWRGHTDQACRESFPCSAGKVY----LPCGPS
SLPYCYGKDSTSSLYPTLPSCRALPEAGPITEGCFCPENTMIFSSDAQVCV-PANCSWLG
----------GVPGHTISTDCQECTCQDSSQNLTCHRKPCP---LPPACPLPGLVPVPTA
PKAGQCCPQFVCACNTSYCP-EPQH-CPKGSRLVLTHEEGACCPSQICG---IGCNVNGT
------VYQPGAVVSSS--LCERCWCEAASSPPSGSFLVSCETQICN-THCPLGFEYQAQ
SGQCCGKCVAVSCHDLPVRGTY-PASFQPG----ESWSDP-ENRCVTYRCEKHQDRLEVV
TV---ENCPVL--A-----QDQARLSSDGCCFVCP-H--T----------SCTLHHRNQT
IRQGSCSSATPVRLSYCQGNCGNSTSMYSLDTYTVERKCQCCQELRTSRKKVSLTCADGS
SRTFSYTQAEACGCLGQQCHSPGDTSHSGSSESESKK--SKEQSQESGSSSWEGLPRPPQ
-----------

----MGSRSWSWALLWASVALFTVWPAESQSQ-VEPS----LEHT--------------E
LTADGQKVYSVPTSSSTQHVTFIPPITVFP--SVSPVNLAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
YMFRFPGLCNYVFSSHCGATYEDFNIQLRRGLEGSRP-MVTHVVLRAQGLVIELSNGSVL
VDGQ----------VELPYSRAGLLMEKSSGYVKVGIRLVLTFL-WN-E----DSAL---
----LELDSKYTNQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 335)

AVNEF---------YAHNTRLTPVQFGNLQKLDG
PTEQCQDTLPSA-VNNCTDT-----------ENI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CRHILLGPAFAECTALVDVNMYLDAC
VQDLCLC------P----TCPCTTFAEYSRQCAHAGGHPQNWRTPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CN--WE

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMEH
HECSSPCVD-----TCSNPQRSQLCEDHCVDGCFCPPG------------TVLDDIKHL-
---GCLPLEQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTHGGHTYAPGESFNTSCSSCTCFGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGSHIF
TYDEKLYNVHGDCGYILS-KKCADSGFTVLVDLRKCGVTDTENCLKAVTLSLNSGDMV-I
RIQANGAVFLNSIF--TQLPLSAANTTIFSPSSFFIVVQTGL-GLQLQVQLVP-IMQVFV
RLDPSYRGQMC-----GLCGNFNQNQADDFTALSGVVEGTGA-AFS------NTWKTQAS
CPNDKNTFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSYS
VE-TENYAQE

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1458)

WCSKLT-ESSGVFSACHATVSPAPFYSNCIFDTCNCENSEDCMCAALSSY
VHACAAKGVLLSGWRD-

ENSGT00760000118896_5_Linker_14_15 (1458, 1467)

SVCFKYMNN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPQNKSYSYAVSTCEPTCRSLSE-ADVTCGVSFV
PVDGCTCPEGTFLNNKGHCVRDEECPCFFHGTVVAPGEFVTDNGVA------SLTCLS--
---SP---ECQAPMVYLDCNNASVGDKGAE-CLRSCHTLD---VDC--FSTHCVSGCVCP
SGLVADGNGGCIA-EENCPCVHNEATYTPGEIIRDNTLVCNDLSFHS----TCRNRRWEC
TDRPCMGA

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CVAYGDGHFVTFDGERYIFEGSCEYTLAQD--YCRGNTSTDGTFRIVTENVP
CGTTGTTCSKAIKIFVE-----------------------------------SYELILHE
GNFKVVERR-SSGDVPYKIRYMGIFLVIEIRSGIVVSWDRKTSVFVRLQQHYKGRVCGLC
GNFDDNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVGDV-------LEFGNSWKFSPSCPDAPVPKDPCTANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

KCSVINSATFAACHS--QVDSTKYYEACVHDVCACDSGGDCECFCTAVAAYAQACR
DVGVCLSWR-TPDICPLFCDYYNPHGECEWHYQPCGAPCLKTCRNPAGHCLVDLPGLE--
--GCYPQCPPSQP--FFNEDQMKCVA--QCGC---------YDDDGKY------HDI-GT
QVPTAENCQSCL--------CTP-GGLQCVHNLT----ACTCTYEGHTYHYNDVVYNTTD
GLGACLVAICKDNGTILRTAEECPEVL----STT-PFTFTTT--LASGAT----------
------------------------------------------------------------
-----------------------------SGSA---------------------------
------------------------------------------------------------
--------PTVPPVSTVCVH----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSIWYDESYPEPGMTGGDFETFENLRQKGHQVCQTPA---AIECRAEKFPSKDLQELG
QKVNCDPSWGLKCLNSEQSP--P-ICYNYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCDYVP--CASSLTSGTSTTH-----
----------------------------------------------------SLSEITSE
HTLPTLSTQTASSVSQSRRSWTTEGKETSLDIIHSSRQTVTFTSKISATSHPIVSTNSVS
SLPASSPTWTTIVKKTTSHTMP-------------------------SSQPKSV------
----------------------------------------------------FTSDTGST
STVSTVTEKVSSPVT-STSCQPQC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTKWFDVDYPTSDSEGGDIETYDKIRATG-EDICG
QP---QDIQCVAQNYPYVSLDRLDQ-K-VKCDVNFG-LVCHNRDQG--GQFGMCYN---F
-MIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3295)

CCN-VSHCQGPATSAGSPPTPG--------------------------------
-----------------TATTASS-------R----------------------SVTHTS
WSVS----RKP-----------TIIS----------------------------------
-------------------TTESISSSPQ-------NTVLTTASSTAIPTPRETQTSPWL
T------------------------------SVSS-TPTTMSTTSTGCKF-QCS

PF13330 // ENSGT00760000118896_5_Domain_33 (3295, 3391)

WT-DWL
DSDKPQPGQFGGDIETYYHIRNKTGIQICKKP-V---DIECEAILFPNM-SFQQLGQEVV
-CNVDFGLICRNSKQAN-NQTCFNYHIRVLCCEEDTSCVST--TGS-LSTTSAGPLFPIS
I---S--------------------------------------PTGKPNT----------
-----------------------------------------TSQTASSKAPSTA-TPTTS
TR-------------------------------FSR-T-----------TTSLWNS---L
---------------------------P-FSTSNTSTTPS--------KPRSTSMTTNNF
QTL---------------TT-RDIS----------------KSHSKLPTS----THVTTT
S-------------------------------SA---TAVSMDLVSKSYSS---------
-----------------------------------TSLTTPGPSYSP-------------
-----------------------------------------------PGSTN--------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MSSATA-----------------------
------------ASMTTTIT---------------------------HAR----------
--------TTPEI-TGAPLASTTATLSTQ-MVTSTASMVTQSVSSL-VTSTSCQPQC

PF13330 // ENSGT00760000118896_5_Domain_37 (4198, 4292)

QWT
KWFDVDYPTSDSEGGDIETYDKIRATGEDICGQ-PQ---DIQCVAQNYPYVSLDRLDQKV
KCDVNFGLVCHNRDQGGQFGMCYNF-MIRVLCCN-VSH--CQGPATSAGSPPTPGTA---
------------------------------------------------------------
------------------------------------------------------------
----TTATQTLSS-----------------------------------------KNYPNT
IPDETWSPSGSITSIYASDMPTPGI-----------------------------------
--------LTTSVSSPPGTPLTAT------------------------------SKTTQ-
-----------HPVSPAS------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----SS--------------------------TISSP-----------------------
---------VTSTSC-QP-----------------------------QC-----------
------------------------------------------------------------
------

PF13330 // ENSGT00760000118896_5_Domain_43 (5407, 5539)

QWTKWFDVDYPTSDSEGGDIETYDKIRA---TGEDICGQPQDIQCVAQNYQDVS
FDMLNQK------------VKC------------------D-------VNFG-LVCHNRD
QRGQF--GMCYNFMIRVL

ENSGT00760000118896_5_Linker_43_44 (5539, 5812)

CCNVSHCQGPAT------------------------SAGSPP
TP-GTSTTATQT-LSSKPWPNTTLNVTRTHSAFTTLATSLSKTLPGSSHTATLVTSS---
GRSPPHVSSVKETSNSEKVSSIYTTLDILHKTLQSSTPALTTKQTSSPGIWTKILTVTAG
SISSKL-------------------------PPTSL----------ELTTGI--------
-----KELSTPTPRMLPV--------T-MT------NAITSQETTHCQPKC

PF13330 // ENSGT00760000118896_5_Domain_44 (5812, 5924)

KWT------
EWFDVDSPTSGV-VRGDMETYENIRA-AGKKICQAPE---KIECR-AENYPEVSIDQVGQ
RLSCN-----------LETGLVCQNEDQTGDFKMCFNYNIRVF

ENSGT00760000118896_5_Linker_44_46 (5924, 6728)

CCDDY------------
-----SH-CPSTTAIPHTSTTN-------KTK----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------VSKEVTTM---------------------------------------
------------------------------------------------------------
-------------------------------ATSSSTGQGH-------------------
----------------------------------------STKAT---------------
------------------------------------TSS-------------NTAQSLM-
------------------------------------------------------------
---------------------------TSIAHT--GST----------------------
------------------------------------------------------------
---------------PST--------------------YS--------------------
----------------------------------------GSS-------------LMTS
TSCQPQC

PF13330 // ENSGT00760000118896_5_Domain_46 (6728, 6821)

QWTKWFDVDYPTSDSEGGDIETYDKIRATGEDICGQPQDIQCVAQNYPYVSLD
TLDQKVKCDVNFGL--VCHNRDQRGQFGMCYNFMI--RVL

ENSGT00760000118896_5_Linker_46_50 (6821, 7191)

CCNVSHCQGPATSAGSPPTP
---GTATTATQT-------LSSKNYPNTIPDETWS------PSG--SITSIYASDMPTPG
ILTTSVSSPPGTPLTATSKTT---------------------------------------
------------------------------------------------------------
------------QHPVSPAS----------------------------------------
------------------------------------------------------------
---------------------------------SSTISSPVTSTSCQPQC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

QWTKWFDVDY
PTSDSEGGDIETYDKIRATGEDICGQP-Q---DIQCVAQNYPYVSL---DTLDQKVKCDV
NFGLVCHNRDQRGQFGMCY---NFMIRVL

ENSGT00760000118896_5_Linker_50_53 (7290, 7954)

CCNVS-HCQGP-ATSA-----GSPP------
----------------------------------------------TPGTPGTTTT----
----------------ARVSNTAINTS---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------WASSATLSSTSAT--------------------------------
---------------------------SMSTSTS-KE-----------------------
------------------------------------------------------------
-TQP--------SSLLSTRTTLLASSKGCTPRC

PF13330 // ENSGT00760000118896_5_Domain_53 (7954, 8050)

TWTDWIDQSSPTPG---NSGGEFETFT
NIRASGIAICEKPL----DLECDIVRQPNMPWQESRQVINCTLEFGLVCRNLDQMGPSSA
CLDYRIRVL

ENSGT00760000118896_5_Linker_53_54 (8050, 8718)

CCDDYSHCLP-----------------------------------------
--------------------------------------------------WSTHTPTVP-
FTT---------------------------------------------------------
------------------------------------------------------------
-----------------------------TV-----------------------------
----------------------------SSS-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------SES--------------------------------------------------
-------------------------TFQTKHRSSSPVP---------STQASTW------
-----TTFPDSGCVPRC

PF13330 // ENSGT00760000118896_5_Domain_54 (8718, 8941)

TWTD-----WFDADFPN---------------------PGPR-
-------GGDFEVYAVLREVGFVFCDQP----RDIQCR----SEKEPDKPLESLEQ----
-------VVQ------CDVRFGLICKN------INQTGPL------QYCDN---------
------------------------------------------------------YHVRLL
CCDNISHCTTSPMATSATIPSTSPLMS----SHT------------------------SP
TLNTM-------------------------------------------------------
----------------------------------------------------T-------
------------------------------------------------------SSPE--
----------------VTGSIMSHSSSLGPTHTSP-VLTTGTSPVATGPTVVPSSTSET-
-----------------THTSQ----------V-SHS-S-QVTFSMPTVSPL-GL---ST
LRP---TVFSSQSLSPSSCFCQA-F----GQL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--FLPGDVIYN------KTD--------GAGCQFYATCSQYCDIDRFQ-GACPSSSPPVP
ST----------LP----------------------------------------------
------------------------------------------PLSSLPPGCDNTIPPRQV
NESWTLENCTVARCQGNN-QIILLEPE--PVDNVTCVNKHLPIKVWDQ-EPCH-FHYECE
C-----------------F

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGRSHYLTFDGTSYTFPDNCSSVLMKEIHPRHGNLSIL
AHSYYCGATT--N-VTFCPRALSVYYNSMEIVLTI-TTTASGKEESLIIWDQMWIRSGSS
KNGVTVSLSGTTTMSVNISTIGTSIIFDGHIFQIWLPYRYFSNNTEGRCGTCTNSQTDDC
RRPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TIASNCQDMAKDWLVPG----NSNNSCLAQPSPPPSTTSQPPV------------
--SSTP---TSTPCPTA-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CE--LM-------LSQVFAECHRLIPPDTFFNSCVSDHCS
AN---FTGMLCQSLEAYATLCRAQGVCVTWRNATGGLCDFS--CPPTKEY----RPCGPL
HPVSCSSRTLSVS--------T-----GTLAEGCFCPENQLLFNSHMDICV-LE-C----
-P-------LSVPGENWTSNCQSCVCDPSSVSVHCEPVQCESQKELPECTEAGSVSVTRP
KADNPCCPETVCVCDATTCP-QSVPKCDPGYELIQTHLNGNCCPNFTCRP--LTCTYNKT
------LYGVGANFPGD-DLCQTCTCFSVG---NQQPKVQCREILCT-TTCPRGFKYMPT
PQQCCGQCVQNACLTPEG------QAVQPN----ETWVNSPVDNCTVYHCKVETGIHILT
PT--PTACPDV--S-----NCRGTLRKTGCCYSCEKEDSS----------RCRVHVNTTI
LQHNGCETEVAVNITFCEGSCPG-KSKYSMETQTMEHQCTCCQESKVHDVAVTMQCPNGT
VIQHTYTHIDECSCALACSSLPMTSMNTS-------------------------------
-----------

----MGVGQRRLAPLWALALALA--CAQHTGQAQDSS----AEPSY-------EHP---D
VSPVAQGPSGD----PLRVVTILPPLRTTP--VVRALNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSAHCGAAYEDFNVQLRRSRDSNTT-TLSRVVMKLDGMVVELTQSSVL
VNG---------RLVRLPFSQSGVLIEHSSSYLKVVARLGLVFM-WN-QD---DSLL---
----LELDNKYANQTCGLCGDFNGV

ENSGT00760000118896_5_Linker_0_4 (266, 333)

PIFNE-F--------FSHNVKLTPFEFGNLQKMDG
PMEQCQDPIPAS-PANCS--T---------DV

PF08742 // ENSGT00760000118896_5_Domain_4 (333, 409)

GVCKEILSSQMFSSCNTLVDVGSYVEAC
QQDLCLCEHS---N--LTSCLCHTLAEYSRQCAHAGGLPRDWRSPDLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--VK

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNLQY
RECGSPCSD-----TCSNREHSQLCEDHCVAGCFCPE---G---------MVLDDIGQT-
---GCVPVSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCVYNGATYASGAVYSTDCTNCTCSGGRWSCQEVPCLGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGAHFS
TFDERLYTVHGDCTYVLT-KPCS-SAFTVLAELRKCGLTDSETCLKSLTLSLDGGQTV-I
VVKA-SEVFVNQIY--TQLPVSAANVTLFRPSTFFIIVQTNL-GLQLEVQLVP-AMQVFV
RLAPTLRGLTC-----GLCGNFNSVQADDFRTLSGVVEGTAA-AFA------NTWKTQAA
CPNVKNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

KYAQHWCSQLT-DPQGPFAGCHGAVNPSSYYSNCMFDTCNCEKSEVCLCAALSSY
VWACAARGVLLSGWRD-GV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CTKPMTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYQYHISTCQPTCRARSE-DDVTCGISFV
PVDGCTCPNDTFLDDTGKCVPATS

ENSGT00760000118896_5_Linker_15_17 (1525, 1588)

CPCYLGGSVVPNGESLHESGAVCTCTQGRLTCIGGH
TP-AP---VCASPMVYFDCRNATPGAA

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GAG-CQKSCHTLD---MDC--YSSQCVSGCVCP
QGLVADGQGGCIA-AADCPCVHNEASYQAGQTIRVGCNT-------C----TCKSRVWQC
TDEPCLA-

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CAVYGDGHYLTFDGQRYSFSGDCEYTLVQD--HCGQNSSAQEAFRVVTENVP
CGTTGTTCSKAIKIFLG-----------------------------------SYELKLSD
GKVEVIEKG-AGREVPYSIRHMGIYLVVDTEVGLLLLWDKKTSIFIRLSPEFKGRVCGLC
GNFDDNAVNDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1920)

QSVVGNA-------LEFGNSWKFSPSCPDAPAPKDPCSANPYRK

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1996)

S
WAQKQCSIINSATFATCHA--HVEPAKYYEACVSDACACDSGGDCECFCTAVAAYAQACH
EVGVCVSWR-SPDVCPLFCDYYNPEGQCEWHYQPCGAPCMKTCQNPSGQCLHDVRGLE--
--GCYPKCPAEAP--LFDEDQMQCVA--TCPQ-------SPCRIQGKS------YQP-GT
PVPSDENCHSCV--------CTE-SGVQCTYDAE----ACVCTYDGQRFRPGHVIYHTTD
GTGGCISAHCGTNGTIDRRVYACSSTTPA--P---QTTFSFS--TAPLVVSSTRLPVTYP
SPTE---S--------------------------------------------TPSSAPA-
------SPTGT-----------TPRP--TPST----------------------------
------------------------------------------------------------
----------ASTSPHPDCG----------------------------------------
----------------------------------------------------------EE
CQWSAWLDISRPGRGIDSGDFDTLENLRAHGYQVCRVPR---AVECRAEAAPEVPLQILG
QRVECSPAVGLTCYNKDQAS--G-LCDNYQIKILCCSPLP--CTTSGGAAQTTPPATSRT
TET--------------GPT--P-GTSRPT------------------------------
----------TTGP----------------------------------------------
-----------TTLSTTGTPT--------------------------PAPRTSI------
---------TVK--TT--LSTSSPMS--VST--TASATSS----E-------STKAPGSS
EVP---GKPTPPEPTHISCLQEFCSWTRWIDNSYPGPGRNSGDFDTFQNLRSKG-YKFCE
KP---SKVECRAQAFPDTPLEELGQ-D-VICDNKLG-LLCLNKNQL----PPICYN---Y
-EIQIQCCELVDTCRQSTTAQATGERSHS--------------TPQES-------RVK--
------------------TESPWTT----------------------ATH----------
---------------FVST---K-------------------------------------
-------------------------Q-----------TGT------SSGTGLRTS-----
---------------------------G----VIASTPTVTTLGTTNCQP-QCKWT-KWF
DVEFPSPGPHGGDSETYSNILR-SGEEICTRP-EYITHLECRAESHPEV-SIEQLGQVVQ
-CDPDVGLVCRNRDQEGHGSTCLNYEIRVLCCEPREGCPPPTPVPV-PSTSRVSSS----
-------S---------PE--------AT-------SHVATSRTTSVP------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------KTSRT-----------------------------------
------------------------------------------------------------
-------------------------------------------------------PVPRP
STTSA--PGPRP------------------------------------TSVPETSTKTEV
-RTST--------TSAPGT-------------------------SP--------------
-------------------------------------------------TPVQKTSRTSV
PRPSKA--TAPGSS-P------STELRTSTTSVPGSSP------------TSGHRA----
----GTSPAP--AS--------------------STTSVGGPET----------------
-------------------------------------------SHSPPATSRCQPQCKWT
KWFDVEFPSPGPHGGDSETYSNILRSGEEICTR-PEYITHLECRAESHPEVSIEQLGQVV
QCDPDVGLVCRNRDQEGHGSTCLNY-EIRVLCCE-PREG-CPPPTPVP---VPSTSRV--
---------------------------------S---SSSPEATSH---V----------
-------------------ATSRTTSVPKTSR------------------------TPVP
RPSTTSAP----------------------------------------------------
------------GPRPTSVPETSTK-----------------------------------
------------------------------------------------------TE----
------------VRTSTTSAPGTS------------------------------PTPVQK
TSRT----SVPRP-SKATAPGSSPSTELRTSTTSVPGSSPTSGHRAGTSPAPA-------
---------------------------------SSTTSVGGPETSHSPPAT-----SRCQ
PQCK--WTKW---FDVEFPS-------------------PGAPRRATL------------
-----RPTATSSAAGRRS--APG-----LSTSRTWSAG--PR-AT----PRSASSSW---
------------------------------------------------------------
---------------------------------------------------ARWCSATPT
WAWA--------------------------------------------------------
--------------TAAR------AST--------------------------TR-----
---SACCCPPPTPVPVPSTSRVSS------------------------------SSPE--
-------ATSHVATSRT--------TSVPKT--SRTPVPRPSTTSVPGPRPTS---VPE-
-------TSTK-------------TEVRTS--TTSAPGTSPTPVQK--------------
------------------------------------------------------------
--------------------TSRTSVPRPSK-----------ATAPG-------------
------------------------------------------------------------
---------------------------------------------------------SSP
STE-------------LRTSTTSVPGSS---P--------------------TSGHR---
------------------------------------------------------------
------------------------------------------------------------
--------AG--TSPAPA--------SSTTSVGGPETSHSPPATSRCQPQCKWT------
KWFDVEFPSPGP-HGGDSETYSNILR-SGEEICTRPEYITHLECR-AESHPEVSIEQLGQ
VVQCD-----------PDVGLVCRNRDQEGHGSTCLNYEIRVLCCEL-------------
-----REGCPLPTPVCPAS-----------------------------------------
--PGTS----RV-SS-----------------------SS--------------------
----------PEAT-------SHVATSRTT------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------SVPETSRTPVPRPSTTSA-------------------
-------------------------------------------PGPRPTSVPETST----
---KTEVRTS--------------TT---SAPG---------------------------
------------------------------------------------TSPTPVQKT---
------------------------------------------------------------
--SRTSVPRPSKAT--------AP------------------------------------
----------------------------------------GSSPSTELR-----------
--------TSTT------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------SVPG------------------S
SPTS--G-----------------------------------------------------
-----------------------HR---AGTSPA--PAS---------------------
---------------STTSVGGPET-----------SHSPPATSRCQPQCKWTKWFDVEF
PSPGPHGGDSETYSNILRSGEELCTRP-EYITHLECRAESHPEVSI---EQLGQVVQCDP
DVGLVCRNRDQEGHGSTCL---NYEIRVLCCEPREGCPPPTPVPV-PSTSRVSSS-----
---------------------------S----------PEAT----SHVATSRTTSVPKT
SRTPVPRPSTT--------------------------------------------SV---
--------------------PGPRP-----------------------------------
-------------T--SVPETSTKTE-----------VRT------S-------------
------TTSA----------------------------PGTSPTPVQ-------------
------------------KTSRTSVPRPSKATA-------PGS-----SP----STELRT
STTSVPGS----------------------------------------------------
--SP----TSGH-----RA-------------------------GT-----SPAPASSTT
SVG--------------------------GPET-----------------SHSP------
------------------------------------------------------------
-----------------------PATSRCQPQCKWTKWFDVEFPSPG---PHGGDSETYS
NILRSGEELCTRPE-YITHLECRAESHPEVSIEQLGQVVQCDPDVGLVCRNRDQEGHGST
CLNYEIRVLCCEPREGCPPPTPV-PVPS-------TSRVSSSSP----------EATSHV
ATSRTTSVPKTSRTPVPRP------------STT----SVPGPRPTSVPETST-KTEVR-
--TSTTSAPGTSPT--------PVQKTSRTSVPRPSKATAPGSSP----STELR----TS
TTSVPGSSPTSGHR--------AGTSPA--------------------------------
--------PASSTTSVGGPETSHSPPATS---DASH--SASGPSGS----TWNS------
--RPPGPT--AATL----RPTATS-----------SAAGRS-------------------
-SAPGLSTSRTWSAGPRATPRSASS--SWARWCSATPTWAWCAGTGTRRATAA---RAST
TRS----ACCAA---SPAKAPPPTPVPVPS----TSRVSS--SSPEATSHVATSRTT---
SVPKTS-RT-PVPRP--------------STTSAPGPRPT----------SVPETSTKTE
VRTSTTSAPGTSPTPVQKTSRTSVPRPSKATAPGSSPSTELRTSTTSVPGSSPTSGHRAG
TSPA---------------------------------PA--------SSTTSVGGPETSH
-----SPPATSRCQPQCKWTK-----WFDVEFPS---------------------PGPH-
-------GGDSETYSNILRSGEELCTRPEY-ITHLECR----AESHPEVSIEQLGQ----
-------VVQ------CDPDVGLVCRN------RDQEGHG------STCLNYEIRVLC--
----CEPREGCPP---PTPVPVPSTS-RVSSSS---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PEATSHVATS--
--------------------------------------RTT-S-VP---KTS-RT-----
-PS---LS-S-PLPSPSTCYCSV-S----HKL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--YPAGSIIYQ------QID--------LAGHCYYAVCSLDCHVVRRSDETCPTSTPPPA
PAT--SSPASSPSG----------------------------------------------
------------------------------------------PVPVTHHGCSNISPPRMK
GETWNMPNCSQATCEGHN-IITLQPRQCPTVQEPTCANGYPAVQVVDQ-DSCC-PHYECQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9905)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVL
IDNYFCDAE---D-GLSCPQSIIVEYRQDRVMMTR-KP-VRGVMTNEIIFNGKVVSPGFQ
KDGIDVSQIG-IKMYVTIPEIGVQVMFSGLIFSVEVPFSKFANNTEGQCGTCTNDPKEEC
RLPG

ENSGT00760000118896_5_Linker_56_57 (9905, 9978)

GAVVASCSEMAGHWKVTN----PDQPSCHGPPPTPTAGP-----------------
--TPTP---SPASCPPS

PF08742 // ENSGT00760000118896_5_Domain_57 (9978, 10054)

-PICQ--LI-------LSEVFEPCHSMISPGPFYQGCVFDQCH
VT---DLDVVCSGLELYAALCASQGVCIDWRGRTNHTCSFT--CPPHKVY----RPCGPS
NPPHCHGDDHISL--------MALQEAGPITEGCFCPEDMMLFSTSVDVCV-PTGCPRCQ
----GPHGEPVEPGHNVSIDCQECTCDGSTWKMSCRRQSCPLPH----CPEPGFVPVAAA
PQAGQCCPQYSCACNTSSCP-A-PLDCPKGSRLTLAYEEGSCCPKQNCSW--TVCSVNG-
-----TLYQPGAVVS-S-TLCETCRCEVTGGPESDTFVISCETQICN-TYCPVGFEYQAR
SGQCCGECVQMACVMNTSDS--SAHLFYPG----KSWSDP-GNRCVTYECEKHRDGLVVV
TM--RKACPQLSCP-----LDQARLSEDGCCLSCP-Q--P----QPQNRSTCAVYDKHQV
IRQQGCSSSGPVRLTYCQGNCGDTTSMYSLEANRVERTCRCCQELRVSLRNVTLHCADGS
SRAFSYTEVEECGCVGLRC-----------------------------------------
-----------

----MGALSTCRTLVLALAAVLLVQQAETRGPAEPSW----GSA----------------
---GPTTDGGAPTSSPTRRVSFVPPVTVFP--SLSPLNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFHFPGLCNYVFSEHCGAAYEDFNVQLRRGLVGSRP-VVTRVVIKAQGLVLEASNGSVL
VNGQR---------EELPYSRTGLLVEQSGDYVKVSIRLVLTFL-WN-GE---DSAL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 342)

AFNEF---------YAHNARLTPLQFGNLQKLDG
PTEQCPDPLPLP-ANNCTDE-----------EGICYHTLLG

PF08742 // ENSGT00760000118896_5_Domain_4 (342, 408)

PAFAECHALVDSAPYLAAC
AQDLCRC------P----TCPCATFVEYSRQCAHAGGQPQNWRRPEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPVNMLH
QECGSPCVD-----TCSNPQRAQLCEDHCVDGCFCPPG------------TVLDDVTHS-
---GCLPLEQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGHTYSPGASVNTTCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KKCADGSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA-I
RVQADGSVFLNSIY--TQLPLSAANITLFTPSSFFIVVHTGL-GLQLLVQLVP-LMQVFV
RLDPTHQGQMC-----GLCGNFNQNQADDFTALSGVVEATGT-AFA------NTWKAQAA
CANARNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPTGSFSRCHSIINPKPFHSNCLFDTCNCERSEDCLCAALSSY
VHACAAKGVQLSGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKYMQN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQRYAYVVDACQPTCRGLSE-ADVTCSVSFV
PVDGCTCPTGTFLNDAGACVPARECPCYVHGTVLAPGEVVHDEGAGPGCFVAHLCVF---
--------------------------------------------------------THTP
PGDLGAGRAG--------PC----------EQAPSLAPR-------S----TCRNRRWEC
SHRLCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CVAYGDGHFITFDGERYSFEGSCEYILAQD--YCGDNA-THGTFRIVTENIP
CGTTGTTCSKAIKLFVE-----------------------------------SYELILQE
GAFKAVARG-PGGDPPYKIRYMGIFLVIETR-GMAVSWDRKTSVFIRLHQDYKGRVCGLC
GNFDDHAINDFATR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SRSVVGDV-------LEFGNSWKLSPSCPDALAPKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACRS--QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH
DAGLCVSWR-TPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLE--
--GCYPRCPPSQP--FFNEDQMKCVA--QCGC---------YDRDENY------YDV-GT
RVPTAENCQSCN--------CTP-SGIQCAHSLE----ACTCTYEDRTYGYQDVIYNTTD
GLGACLIAICGSNGTIVRKAVACPGTP----ATT-PFTFTTS--WVPHST----------
------------------------------------------------------------
-----------------------------TSP----------------------------
------------------------------------------------------------
----------ALPVSTVCVR----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSSWYNGHHPEPGLGGGDFETFENLRQRGYQVCPVPA---DIECRAGQLPDMTLGELG
QQVDCDRVRGLMCANSQQSP--P-LCHDYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCEYVP--CGPSLAPSTSPQP-----
----------------------------------------------------SLSAST-E
PAVPTPT-----------------------------------------------------
Q-----TT---ATEKTTLWVIP-------------------------SIRSTAA------
----------------------------------------------------LTSQTGSS
SGPTTV----TSLAPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTEWFDEDYPKSEQLGGDVESYDKIRAAG-GHLCE
QP---KDIECQAESFPNWSLAQVGQ-K-VHCDVRFG-LVCRNWEQE--GIFKMCYN---Y
-RIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCG-TDHCRGRATTPPPATEPE--------------------------------
-----------------TATT--TTTQVLFSTLQSTSSLGVT-----STTAVP-------
-TLSKGLTS-P-----------RYTGTLGTATTGGPTVPAGSTEP-TVPGVATSSLPTR-
SVLPGTTGSSGTWRPSQAPTPAPTTMATSRAHLTG--TAS-S----GSKQPLTTSLAPT-
-------L-SSELLTSQAETSTPRTETT----LSPSTEATTSQSTTRCQP-KC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDFPTSGVAGGDMETFENIRA-AGGKMCWAP-E---SIECRAENYPEV-SIDQIGQVLT
-CSLETGLICKNEDQTGRFNMCFNYNVRVLCCDD-SHCPHTAAPTP-TSST---------
QAPRL-----------------------------------TSMGATSP------------
--------------TVTAS---T---------------------AIATWST---------
--------------------------------------KSPVVTGSSTLATT--------
------------------------------------------------------------
----------------------QTG----------PSFSKSTERV---------------
--------S--L-----PSPSAPP---P----------------STTSLLP---------
------------------------------------------------------------
-------------------------TRG---------QQTSQTP-----SMPTSPTVTST
PTT---------------------------------------------------------
------------------------------------------------------------
--------------------------------SPLVTT----------------------
-----------------H----------------------------VHTTL------RT-
------------------------SSSGSTIR-------TTLPSGPPSSSTGCVPRC

PF13330 // ENSGT00760000118896_5_Domain_37 (4198, 4292)

TWT
DWFDEDYPSSDPDGGDFETFGVIRSAGHTFCEQ-PW---DIECRSEKEPNQPLEALGQVV
QCDVSIGLVCRNRDQSGPLWYCHNF-HVRLLCCD-DSH--CATTSTSTGSTGTTSTS---
------------------------------------------------------------
------------------------------------------------------TGSTAT
TPTSTGSMGTTSTSTGSTASTGSTATTPTSTGPMVTTPTSTGSTVIVPVSTSSTAATPRS
TGATPRS-----TGATARHSSTPGTAHTAKVLTTTAITTQATSSIATPSSTSSTAQTPKA
LTTTTTTTVAASSMVTSHTPAGTT------------------------------EPTTKA
TVTMPTGSMATASSSQGTVHTPKVLT-TTTITTMATTSKATPSPTPATAATPNVLTTMTT
TPTVTG--SKATP---SSSPGT--------------------------------------
---------------------------------APTLPAL-TSTATTPTAT---------
-------------SFTAIPS----------------------------------------
----------------------------SSLGTT--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------WTLTA---QT------TTPTATMSTAR-------------------------
------------------------------------------------------PSSTSE
TAHIFTGLTTMATTTGA--------TGSMATP-YSSP-----------------------
---------GTAHT----------TKVLTT--TTMGFTATPSSSPKTAR-----------
------------------------------------------------------------
------TLPVWIRTNTTPT-TRGSRVT-SSSIPGTTHTPTVLTNTTKTV----ATGS--A
ATLFTSETAHTSKVLTTMAITTSSTTTPSSSPGTASTLTALITTTTTPTTSGYTVTPSSI
PGTTHTPTVLTNTTTTVAT-GS-----MATPSSSP------------------QTAGTPP
ALATTVTTITAT--GSTTTPSST-SGTT---PISPVLT-TTATTPAATSTTVAPSSALGT
THTPPVLSTTATTHGRS---------------------QLPESPRTVPTAWTSMA--PSG
TTHITEPSTVTSHTPAGTTGATRPSTPALSSPHTHSRTTESPPSPGKTTPGLTTATS--R
TTATATPSETRTSTLLPS--------SPTS------APTTPVVSTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WS------
DWLDYSYPTLGL-SGGDLETYSNIRA-AGGAVCGQPL---GLECR-SQAQPGVPLRELGQ
VVECS-----------LDVGLVCWNRQQVGKFKMCFNYEIRVFCCNY-------------
-----M------------------------------------------------------
-TTGST------------------------------------------------------
--------------------------------------------------------AMPS
STPGMT-EILTEPTTTTIPTVATGSTATPS------------------------------
------------------------------------------------------------
-------------STLGT-TRILTEPTT-TATITVATSSMA-------------------
--------------------------------------TPSSTLASTWILTEPSTT----
------------------------AITTVATGSKATPSSTPGTARLLTEPTTPATITPTT
TAITTVATANPSSTPGTTGILTEPTSTAI-------------------------------
-----------------------TTVATGSTATPSSTPGM-------------TSILTEP
TTTTITTV--------------------------AT-GSTATPSATRETTGILTEPTTTA
TITVATRSTANPSSTPRTTSILTEPTSTAITTVATGSTATPSS-TRGTTGILTEPINTAT
ITVATSSTAMPSSTPGMTSILTEP-IT-----TAITTVATGSMTTPSSSPGTTRLLTEST
--TTAT---ITVATSSMTTP-STQGTTLILT-----------------------------
EPNTTAITTVATG--STVMPSSTLVTTGILTE-PTTTTVTTVATGSTATPSSTLGTTGIL
TEPTTTTVTT-VATGSTVTPSSTLGTTGILTEPTSTTIT---------------------
--------------TVATGSTATPSSTPGTTVILTKPTTTAI-------TTVATG----S
TAMPSSTPGTTTILTEPTTTAITTVVTGSTVIPSSTPQTTQITEVFPSTTAMTEATGSTV
NPSSTPGTTVILTEPATTATITVATGPMATSSSTPGTTWILTEPTTTLTTTVATGSTVTP
SSTPATAATSELLTTTATKPTATGSKATPSTSPG--------------------------
----------------------TASTLPVVLTSTANTPTATSFTAIPSSSLRTTW--NLT
AQTTAPTAT--------LSTAHTSSTP-R---TTHTSTA-LTTTAT---TT---------
-----QATGSTATLLTSGT---AHTSKVLTTMAIT-TSST-ATP------SSSP------
----------------------------------------------G--TASTLTALITT
NTTPTTSSYTV-----TPSSIPGTT-HTPT------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------VL------------------------
------------------TNTTTTVATGSMATPSSSPQTVASS-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-STAPITTAI------TTVAT---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----GSTTSSMAIPSSTPGTTWILTEPTTLA-----TGSTATIPTVPSSSATPFSSPG--
TAGTLPVRTTTATTTMASRSTAIPSSTVGTARTPKVLTTTATRPTATGSTVPSSSTLGT-
-----------------THTPA----------V-LPS-SLP-AFSMSTVSSS-VL---TT
LRP---THLPSSHFS-TPCFCRA-F----GQFFSP------------GE--WTWIMLLYP
FPTCYANLG----LPV---------------PGASCFLPASHACSPLASPGSPWPHPVPT
GHAQSLP---------------------STVPRWNSCSL-----L-RGLCL---LAYLPT
VLFFTGEVIYN------RTD--------RAGCQFYAVCNQQCGLDRFQ-GTCPTSPPPAS
ST----------PL----------------------------------------------
------------------------------------------PSPSPAPGCDNAIPPRQV
NETWTLENCTVARCVGDN-RVALLDPK--PVANVTCVNKHLPIKVSDPSQPCD-FHYECE
C-----------------I

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSVWGSSHYSTFDGTSYTFRGNCTYVLMREIHARLGNLSLY
LHNHYCAAA-----AASCSRALSIHYKSMDIVLTV-TT-VHGKEEDLILFDQIPVSSGFS
KNGVLVSVTGTTTMRVDIPALGVSVTFDGHVFQARLPYSLFHNNTEGQCGTCTNNQRDDC
LQRDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TTTASCKDMAKTWLVPD----SRKEGCWAPTSTPPTASPPAPV------------
--SSAP---TPSLCPPQ-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CD--LM-------LSQVFAECHDLVPLGPFFNACISDGCQ
-G---RPEVPCQSLEAYAALCRARGVCSDWRGATGGLCEIT--CPPTKVY----KPCGPI
QPASCNSRNQNPQ--------L-----EGLAEGCFCPENQILFRAHTDTCV-QA-C----
-ALKDPL-NPFQPGQQWISNCQSCVCDEGSVSVQCTPLPCEAQGQPPPCSHPGFVNVTRP
RADNPCCPETVCVCNTTTCH-QSPPVCPLGQELISTQKEGDCCPTFLCSE--RGWG----
------GTGVGATFPGA-LPCHTCTCLSGD---TQDPTVQCREDACHNTTCPQGFEYKRV
AGQCCGECVQTACLTPGG------PPVQLN----ETWVNSHVDNCTVYYCEVESGVYLLT
PQ--PASCPDV--S-----SCRGSLRKTGCCYSCE-E--D----------FCQVHVNTTV
LWHQGCRT--EVNITFCEGSCPG-ESKYSAEAQAMQHQCTCCQERRVHEETVPLRCPDGS
TVLHTYNHVDECGCTPFCVPAPMAPTYPPGFLAR--------EATAV-------------
-----------

------------------------------------------------------------
--------------------------------VSAALKSSHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DIFHFPGLCNYVFSSHCKSPYEDFNIQIRRVPGPNATTAVSRITLKLDGTVVEMNQDVIL
VHG---------RPVQLPFSQAGILVEKSGTSVKVVAKLGLVFM-WN-QD---DGLL---
----LELDAKYANQTCGLCGDFNGIP

ENSGT00760000118896_5_Linker_0_4 (267, 333)

TTTSSSPMVRKLRDSSLYVRLTAVQFGNLQKMDG
PMEQCQDPIPRA-PQNCT--V---------PF

PF08742 // ENSGT00760000118896_5_Domain_4 (333, 408)

DFCGAILNSAPFFACHALVDVSSYVEAC
RQDVCLCEEA---H--YTACICSTFAEYSRQCAHAGGLPANWRAPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CH--KT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPWNMQY
RECGSPCRD-----TCSNPDQSLLCEDHCTDGCFCPP---G---------TVLDDVAGR-
---GCVPAEQ

ENSGT00760000118896_5_Linker_5_8 (491, 531)

CFCTYNGQSFAPGTFYSTECTNCTCSGGKWSCRDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_8 (531, 593)

CSVTGGAHFS
TFDEKHYTVHGDCSYVLV-KPCGDEAFTVLAELRKCGLTDSETCLKSVTLSVGGGHTG-R
IRIGGTDSYFLRLK--TEPMIWISQLPVFQEVRILIISIDTHRTVNTHATNEP-I-----
GPAPN-LAPPQ-----AFCGEFQQHPGGRLSSMSGVVKARRR-P-F------NTFKTQAD
CPNVRNHFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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--------------------------------------------------------CSLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

KYAQHWCGLLT-DPQGVFALCHAVVNPALYHSNCMFDTCNCEKSEDCLCAALSSY
VQACAARGVVLSGWRA-GV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CTKPMSS

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSLTYRYNISACQPTCRSLSE-PDVTCNIKFF
PVDGCTCEEGTFLDAAGKCVPADS

ENSGT00760000118896_5_Linker_15_17 (1525, 1588)

CPCYHHGSVVPNGESVHDNGALCTCTQGRLDCIGGP
VP-QP---VCAAPMVYFDCSKAPAGVT

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GAE-CQKSCHTLD---MAC--YSTQCVSGCMCP
DGLVSDGEGGCIQ-KENCPCVHNEASYKAGETIQVECNT-------C----TCKNRMWHC
TDESCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CAVYGDGHYITFDGQRYSFNGGCEYTLVQD--HCGKNSSTQGTFRVITENIP
CGTTGTTCSKAIKIFLG-----------------------------------SYELKLSE
GKVEVVEKGDAKEEPPYSIRQMGIYLIVDTNMGLVLLWDKKTSISVQLSPDFKGKVCGLC
GNYDGNSINDFTTRSLSVVGDV-------QEFGNSWKISPSCPDAASPRDPCTTNPYRKA
WAQKQCSLINSDVFA---------------------------------------------
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----MSVGRRKLALLWALALALA--CTRHTGHAQDGS----SESSYK------HHP---A
LSPIARGPSGV----PLRGATVFPSLRTIP--VVRASNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGSFHYKTFDG
DVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAP-TLSRVLMKVDGVVIQLTKGSVL
VNG---------HPVLLPFSQSGVLIQQSSSYTKVEARLGLVLM-WN-HD---DSLL---
----LELDTKYANKTCGLCGDFNGM

ENSGT00760000118896_5_Linker_0_4 (266, 335)

PVVSE-L--------LSHNTKLTPMEFGNLQKMDD
PTDQCQDPVPEP-PRNCS--T---------GFGI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEELLHGQLFSGCVALVDVGSYLEAC
RQDLCFCEDT---D--LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--QK

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPNNMQY
HECRSPCAD-----TCSNQEHSRACEDHCVAGCFCPE---G---------TVLDDIGQT-
---GCVPVSK

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGAHFS
TFDGKQYTVHGDCSYVLT-KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV-V
VIKASGEVFLNQIY--TQLPISAANVTIFRPSTFFIIAQTSL-GLQLNLQLVP-TMQLFM
QLAPKLRGQTC-----GLCGNFNSIQADDFRTLSGVVEATAA-AFF------NTFKTQAA
CPNIRNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSQLT-DADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSY
VHACAAKGVQLGGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKPMTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYHYHVSTCQPTCRSLSE-GDITCSVGFI
PVDGCICPKGTFLDDTGKCVQASN

ENSGT00760000118896_5_Linker_15_17 (1525, 1586)

CPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQ
AP-AP---VCAAPMVFFDCRNATPG

PF01826 // ENSGT00760000118896_5_Domain_17 (1586, 1638)

DTGAG-CQKSCHTLD---MTC--YSPQCVPGCVCP
DGLVADGEGGCIT-AEDCPCVHNEASYRAGQTIRVGCNT-------C----TCDSRMWRC
TDDPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CAVYGDGHYLTFDGQSYSFNGDCEYTLVQN--HCGGKDSTQDSFRVVTENVP
CGTTGTTCSKAIKIFLG-----------------------------------GFELKLSH
GKVEVIGTD-ESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLC
GNFDDIAVNDFATR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SRSVVGDV-------LEFGNSWKLSPSCPDALAPKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACHA--HVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACH
EVGLCVSWR-TPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVRGLE--
--GCYPKCPPEAP--IFDEDKMQCVA--TCPT---PPLPPRCHVHGKS------YRP-GA
VVPSDKNCQSCL--------CTE-RGVECTYKAE----ACVCTYNGQRFHPGDVIYHTTD
GTGGCISARCGANGTIERRVYPCSPTTPV--P---PTTFSFS--TPPLVVSSTHTPSNGP
----SSAHT------------------------------------------GPPSSAWP-
------TTAGT-----------SPRT--RLPT----------------------------
------------------------------------------------------------
----------ASASLPPVCG----------------------------------------
----------------------------------------------------------EK
CL

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPR---SVECRAEDAPGVPLRALG
QRVQCSPDVGLTCRNREQAS--G-LCYNYQIRVQ

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCTPLP--CSTSSSPAQTTPPTTSKT
TET--------------RAS--G--SSAPS------------------------------
----------STPG----------------------------------------------
-----------TVSLSTARTT--------------------------PAPGTAT------
---------SVK--KT--FSTPSPPP--VP----ATSTSS----M-------STTAPGTS
VVS---SKPTPTEPSTSSCLQELC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

TWTEWIDGSYPAPGINGGDFDTFQNLRDEG-YTFCE
SP---RSVQCRAESFPNTPLADLGQ-D-VICSHTEG-LICLNKNQL----PPICYN---Y
-EIRIQ

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCETVNVCRDITRLPKTVATTRPT---PHPTGAQ--------------------
------------------TQTTFTTHMPSASTEQ--------------------------
------------------------------------------------------------
-------------------------P-----------TAT------SR------------
-----------------------GGPTA----TSVTQGTHTTLVTRNCHP-RC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

TWT-KWF
DVDFPSPGPHGGDKETYNNIIR-SGEKICRRP-EEITRLQCRAKSHPEV-SIEHLGQVVQ
-CSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCHMTSTPGSTSSSPAQTTP----
---STTSKT---------------------------TETQA-SGSSAP------------
------------------------------------------------------------
------------------------------------------------------------
--------------SSTPGTVSLSTARTTPAPGTATSV---------------K---KTF
ST-----------------PSPPPV-----------------------------------
------------------------------------------------------------
-------------------------------------------------------PATST
SSMSTTAPGTSVV--------------S--------SKPTPTEPS-TSSCLQELC

PF13330 // ENSGT00760000118896_5_Domain_36 (3896, 4048)

TWTEW
IDGS---------YPAPGING-----------------------------GDFD--TFQN
LRDEGY-------------TFCESPRSVQCRAE-------SFP-----NTPLADLGQDVI
CSHTEGLICLNKNQLPPICYNYEIRIQ

ENSGT00760000118896_5_Linker_36_37 (4048, 4198)

CC-ETV----NVCRDITR-------------PP
KTVATTRPTPHPTGAQTQTTFTTHMPSA------STEQPTATSRGGPTATS---------
---------------------------------------VTQGTHTTPVTRNCHPRC

PF13330 // ENSGT00760000118896_5_Domain_37 (4198, 4292)

TWT
TWFDVDFPSPGPHGGDKETYNNIIRSGEKICRR-PEEITRLQCRAKSHPEVSIEHLGQVV
QCSREEGLVCRNQDQQGPFKMCLNY-EVRVLCCE-TPKG-CPVTSTPVTAPSTPSGRATS
PTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSAS---
----PASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSGPGTTPSPVP
TTSITSAP----------------------------------------------------
------------TTSTTSAPTTSTTSARTSSTTSATTTSRISGPETTPSPVPTTSTTSAT
TTSTTSAPTT-STTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTTSTTSAPTTR
TTSAPKSSTTSAATTSTTSGPETT------------------------------PRPVPT
TSTT----SSPT---------TSTTSAPTTSTTSASTTSTTSGAGTTPSPVPTTSTTSAP
TTSTTSAPISSTTSATTTSTTSGPGTTPSPVPTTSTTSAPTTSTTSGPGTT-----PSAV
PTTSITSAPTTSTN--SAPISSTTSATTTSRISGPETTPSPVPTASTTSASTTSTTSGPG
TTPSPVPTTSTISVPTTSTTSASTTSTTSASTTSTTSG--PG-TTPSPVPTTSTTSA---
PTT---------STTSAPTTST-ISAPTTSTT-------SATTTSTTSAPTPRRTSA---
------------------------PTTSTISASTTS--TTSATTTSTTSATTTSTISAPT
TSTTLSP--T---------------------------TSTTSTTITSTTSAPISST----
-TSTPQTSTTSAPTTSTTSGPGTTSSPVPTTSTTSAPTTSTTSAPTTRTTSVPTSSTTST
ATTSTTSGPGTTPSPVPTT--------------------------------STTSAPTTR
TTSAPTTSTTSAPTTSTTSAPTSSTTSATTT--STISVPTTSTTSVPGTTPSP---VPTT
STISVPTTSTT-------------SASTTS--TTSGPGTTPSPVPTTSTTSAPTTSTTSA
PTTSTISAPTTSTPS--APTTSTTLAPTTST------------TSAPTTSTTSTPTSSTT
SSPQTSTTSASTTSITSGPGTTPSPVPTTST-----------TSAPTTSTTSAATTSTIS
APTTSTTSAPTTSTTSASTAS---------------------------KTSG--------
----------------------L----GTTPSPIP------------------TTSTTSP
PT--------TSTTSASTASKTSGPGTT---P--------------------SPVPTTST
IFAPRTSTT-----------------------------SASTT-----------------
----------------------------------------------STTPG---------
------PGTT--PSPVPTTSTASVSKTSTSHVSISKTTHSQPVTRDCHLRC

PF13330 // ENSGT00760000118896_5_Domain_44 (5812, 5924)

TWT------
KWFDIDFPSPGP-HGGDKETYNNIIR-SGEKICRRPEEITRLQCR-AESHPEVSIEHLGQ
VVQCS-----------REEGLVCRNQDQQGPFKMCLNYEVRVLCCET-------------
-----PKGCPVTSTPVTAPSTP--------------------------------------
--SGRAT----------------------------SPTQSTSSWQKSRT-----------
---------------------TTLVTTSTTST----------------------------
----------------------------PQ------------------------------
------------------------------------------------------------
-------------------TSTTSAPTTSTTSAPTTSTTSA--------PTT--------
--------------------------------------STTSTPQTSISSAPTSSTTSAP
TS----------------STISARTTSIISAPT---------------------------
------------------------------------------------------------
------------------------------------TSTTSSPTTSTTSATT-TSTTSAP
TSSTTSTP----------------------------------------------------
--------------------------------------------QTSKTSAA--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------TSSTTSG---------------SGT
TPSPVTT-----------------------------------------------------
-----------------------TS---------------------T-------------
---A----------------SVSKTS-TSHVSVSKTTHSQPVTRDCHPRC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

TWTKWFDVDF
PSPGPHGGDKETYNNIIRSGEKICRRP-EEITRLQCRAKSHPEVSI---EHLGQVVQCSR
EEGLVCRNQDQQGPFKMCL---NYEVRVL

ENSGT00760000118896_5_Linker_50_53 (7290, 7954)

CCETPKGCPVTSTSVTAPSTPSGRATSPTQS
TSSWQKSRTTTLVTSSITSTTQTSTTSAPTTSTTPASIPST-----TSAPTTSTTSAPTT
STTSAPTTSTT-----STPQTTT--SSAPTSSTTSAPTTS-----TISAPTTSTISAPTT
---------------STTSAPTASTTSAPTST----------------------------
-----SSAPTTNTT--SAPTTSTTSAPITST---IS------APTTS-------------
------TTSTPQTST----ISSPTTS----TTSTPQTSTTSSPTTST-------------
----------------TSAPTTSTTSAPTTSTTS--------------TPQTSISSAPTS
STTSAPTA---------------STISAPT-----------TSTTSFHTTS--------T
TSPPTSSTSSTPQTSKTSA-------------------------ATSSTTSGSG------
---TTPSPVPTTSTAS------------VSKTSTSHVS--------VSKTTHSQ------
------------------------------------------------------------
-----------------------PVTRDCHPRC

PF13330 // ENSGT00760000118896_5_Domain_53 (7954, 8050)

TWTKWFDVDFPSPG---PHGGDKETYN
NIIRSGEKICRRPE-EITRLQCRAESHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKM
CLNYEVRVL

ENSGT00760000118896_5_Linker_53_54 (8050, 8719)

CCETPKGCPVTSTPVTAPSTPSGRATSPTQSTSSWQKSRTTTLVTTSTTST
PQTSTTSAPTTSTIPASTPSTTSAPTTSTTSAPTTSTTSAPTHRTTSGPT---TSTTLA-
PTTSTTSAPTTSTNSAPTTSTISASTTSTISAPTTSTISSPTSSTTSTPQTSKTSAATSS
TTSGSGTTPSPVPTTSTTSASTTSTTSAPTTSTTSGPGTTPSPVPSTSTTSAATTSTTSA
PTTRTTSAPTSSM--TSGPGTTPSPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTSAPI
TSTTSGPGSTPSPVPTTSTTSAPTTSTTSAST-ASTTSGPGTTPSPVPTTSTTSAPT---
TRTT-----------SAST-------------ASTT------SGPGSTPSPVPTTSTTSA
PTTRTTPASTASTTSGPGTTPSPVPTTSTTSASTTSTI----SLPTTSTTSAPITS----
MTSGPGTTPSPVPTTSTTSAPTTSTTSASTASTTSGPGTTPSPVPTTSTTSAPTTSTTSA
STASTTSGPGTSLSPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTS------------A
PTTST---------------------TSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTH
-----SQPVTSDCHPLCA

PF13330 // ENSGT00760000118896_5_Domain_54 (8719, 8878)

WTK-----WFDVDFPS---------------------PGPH-
-------GGDKETYNNIIRSGEKICRRPEE-ITRLQCR----AESHPEVNIEHLGQ----
-------VVQ------CSREEGLVCRN------QDQQGPF------KMCLNYEVRVLC--
----CETPRGCPVTS-VTPYGTSPTN-ALYPSL---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------STSM--------
-----------------VS--------------------------ASVASTS-VAS----
-SS---VASSSVAYSTQTCFCNV-A----DRL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--YPAGSTIYR------HRD--------LAGHCYYALCSQDCQVVRGVDSDCPSTTLPPA
PAT--SPSI---ST----------------------------------------------
------------------------------------------SEPVTELGCPNAVPPRKK
GETWATPNCSEATCEGNN-VISLRPRTCPRVEKPTCANGYPAVKVADQ-DGCC-HHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVL
VDNYFCGAE---D-GLSCPRSIILEYHQDRVVLTR-KP-VHGVMTNEIIFNNKVVSPGFR
KNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFANNTEGQCGTCTNDRKDEC
RTPRG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TVVASCSEMSGLWNVSI----PDQPACHRPHPTPTTVGPTTVGSTTVGPTTVGST
TVGPTT---PPAPCLPS-PI

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CQ--LI-------LSKVFEPCHTVIPPLLFYEGCVFDRCH
MT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFT--CPADKVY----QPCGPS
NPSYCYGNDSASL--------GALPEAGPITEGCFCPEGMTLFSTSAQVCV-PTGCPRCL
----GPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPP---ACPLPGFVPVPAA
PQAGQCCPQYSCACNTSRCP-A-PVGCPEGARAIPTYQEGACCPVQNCSW--TVCSING-
-----TLYQPGAVVS-S-SLCETCRCELPGGPPSDAFVVSCETQICN-THCPVGFEYQEQ
SGQCCGTCVQVACVTNTSKS--PAHLFYPG----ETWSDA-GNHCVTHQCEKHQDGLVVV
TT--KKACPPLSCS-----LDEARMSKDGCCRFCP-P--P--PPPYQNQSTCAVYHRSLI
IQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVTLHCTDGS
SRAFSYTEVEECGCMGRRCPAPGDTQHSEEAEPE--------PSQEAESGSWERGVPVSP
MH---------

-----------------------------------------------------------M
LGVCCPTTTATTTNAPATTVNLIPPLTTNL--LISSFNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGNFHYKTFDG
DIFYFPGLCNYVYASHCKAAYEDFNIQIRRTVVKNAP-TINYITMKLDGVVFEMAKNLVV
VNGNR---------VQLPYSQSGITAERNNMYIKVTAKMGLLFM-WN-ED---DSIL---
----LELNEKYANYTCGLCGDYNGIP

ENSGT00760000118896_5_Linker_0_4 (267, 332)

TYNEF---------FSNNAKLTATEFGNMQKIDG
PTEVCENPNPSP-LNNCTDNF----------

PF08742 // ENSGT00760000118896_5_Domain_4 (332, 409)

DDICHQVLTGPAFSACNSLVEIGEYIKSC
AIDLCNCHQS---I--TDFCTCNTFGEYSRQCAHAGGHPQNWRTPELC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--KT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMQY
QECGSPCTD-----TCSNLERSQICEDHCVDGCFCPA---G---------TVFDDINNT-
---GCIPFET

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCTYNGHSYAPGKSFNTTCKSCTCNRGKWECRDIPCPGS

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CTVEGGSHIS
TYDEKRYNVHGDCTYVLS-KLCENETFAVLGELSNCGLTLTETCLKTIALSINGGQT-II
VIKSGGGVFVNWIY--TQLPVSAPNVIVFRPSTFFIFVVTNF-GLVIEVQLVP-IMQVFV
RLDPSFKGQTC-----GLCGNFNSIEADDFKAISGVVEGTAA-AFA------NTWKTQAS
CPNIQNNFENP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CALS
VQ-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

KYAQHWCGLLV-DSSGPFAKCHSTVNPTVYHTNCLFDTCNCKKSEDCMCAALSSY
VRACAAKGIQLNGWRT-DV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CSKYPTS

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSLSYSYDISSCQPTCRSLSE-PDITCNIKFI
PVDGCTCEKETYMDEYGKCVAARK

ENSGT00760000118896_5_Linker_15_17 (1525, 1588)

CPCYYKGSPVSAGEVVHDDGLVCTCAQGKLSCIGAQ
NQ-T---SVCALPMVYFDCKNFPVGTT

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GAE-CQKSCQILD---IQC--YSTQCISGCMCP
SGLVSDGKGGCIA-EEECPCIHNEATYKPGEEIKVDCNT-------C----VCKNRKWIC
TTEQCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CSVYGDGHYITFDSNRFNFNGDCEYTLVQD--HCGNNSTVNGTFRVVTENIP
CGSTGTTCSKSIKVFLE-----------------------------------AYELILSE
EHLEVVKRENG-RQMPYQVRSMGMYLVIETNNGLILMWDKKTNIFIKLSPDFKSQICGLC
GNYDGNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1920)

QSVVQNV-------LEFGNSWKVSLTCPDANYPKDPCSTNPYRK

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1996)

S
WSQKQCSIINSEVFAACHS--QINPAKYYEECVADACACDTGGDCECFCTAVAAYAQACS
EFGVCIAWR-TPSICPMFCDYYNVKGGCDWHYKPCGAPCMKTCRNPSGICLHKLPGLE--
--GCYPNCPANKP--YFNEDEMKCVD--TCGCY------DA---EGNY------HEP-GG
SFYLRDNCQLCT--------CTM-EGTECTFDAE----ACYCYYEGHTYKYKDVIYNTTD
GIGGCMSATCDINGTINREVFECSGITTTT-----PFTF-ST--VQPTSSAG--ISV--H
FSMPPLFTWV------------TIPLMA-------------PRGKD--------------
SESEAKQLHFFLC---TTGTTMMPP----V------------------------------
------------------------------------------------------------
--------------TTVCVHEEC-------------------------------------
------------------------------------------------------------
-HWSAWYDISSPAEGSKTGDFETFDNLRQKGYRVCKHPR---DVECRATQYPETPLKDLN
QTVTCSKNIGLICNNEDQTT--S-ICDNYEIKILCCSYL--PCVSSPFTTLVTINEYPTA
TTT----------------TV---------KSKTISNP---TTTRTEEGSTTVISVPS-T
SSPPTPAT--SIPA----------------------------------------------
-----------GSAGT---TSAQTG------------------------PNIS-------
------T------------TLTPPQKTTGSTSTVKESTTTES------------------
----------TTL----LSKSPALP-----------------------------------
------------------------------------------------------------
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-----------

------------------------------------------------------------
----------V---------TFIPPLQNTL--KVKAGNPSHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 285)

CST-WGNFHFKNFDG
DIFYFPGVCNYIFASNCKSPYEDFNIQIRRTIVENAT-VITHVIMRLEGAVVELTRASVL
VNGKQ---------IQMPYSHMGVLIERSNNYLKVSAKLGLIFL-WN-EE---DALL---
----VELDKKYANQTCGLCGDFNGIPTNNEF---------ISQN

ENSGT00760000118896_5_Linker_0_4 (285, 318)

AKLTAVQFGNRQKIDG
PTEQCDDPIPSAVLMNC

PF08742 // ENSGT00760000118896_5_Domain_4 (318, 409)

SSEF----------ASICKTVLTSEAFTSCNALVDVQDYIETC
IQDLCHCDSS---M--ADFCMCNTFAEYSRQCAHAGGQPLNWRTSELC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--KS

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMQH
QECGSPCSD-----TCSNPERSALCEDHCTDGCTCPP---G---------MVFDDINGA-
---GCIPRKE

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTYEGETYAPGTSFSSKCRSCTCAGGEWTCVSQSCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CSIEGGSHIT
TFDEKYYSFYGDCSYVLT-KLCDSNDFTVLGDIHKCGLTDTETCLKGVAISLNGGQT-NI
VIQPSGSVFVNMIY--TQLPFSAANVTIFRPSSFFIILQTTF-GLQLQIQIVP-LMQLFI
NLDPSQKGQTC-----GLCGNFNDIQTDDFRTTSGVIEGTSA-AFG------NTWKTQAD
CPDAKITFENP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CTLS
IE-N

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1461)

DKYAQHWCGLLS-DTMGPFAECHSTVNPEVYQKNCMFDTCNCESTEDCMCAALSSY
VRACAAKGILLNGWRN-KVCTKYTNTCPKSLEYTYNVDSCQPTCRSLSE-PDVTCNIKFV
PVDGCTCVNGTYMDESGKCVPASSCPCYYKGMPLSTGEVIHDNGIVCTCSYGKLSCIGEK
P---P--PVCAPPMVYVDCGNATAGVIGAE-CQKSCQTLD---MEC--YNTHCVSGCICP
PNYVLDGKGGCIV-AEECPCVHNGDSYRPGESIRVGCNN-------C----TCRNRKWHC
SEEPCLET

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1877)

CSVYGDGHYTTFDGKRFDFEGDCEYVLIQN--YCGRKGLNQGTFRVITENIP
CGTTGTTCSKSIKVFLE-----------------------------------NYELVLSD
GHSDVIQRSPG-GEMPFQIRSMGIYMVVDTTVGLILMWDKKTSIFIKLSPSFQGHVCGLC
GNYDGNGNNDFTTRSQ

ENSGT00760000118896_5_Linker_20_26 (1877, 1919)

SVVGNV-------LEFANSWKVSSTCPNANQTKDPCTANPYR

PF08742 // ENSGT00760000118896_5_Domain_26 (1919, 1996)

KS
WAQKQCSIITSEVFAKCHS--QVEPNEYYQACVDDACACDTGGDCECFCTAVAAYAQACN
ELDICISWR-TPSICPLFCDYYNPQGECEWHYKPCGAPCMKTCNNPSGKCLHELRGLE--
--GCYPHCPKNKP--YFDEETMACVS--NCGCH------EN----GKH------YKP-GM
QMPSKQNCQACE--------CTN-HGKICKYDEH----ECVCVYEGRTYNYMDVIYNTTD
GIGGCIVATCGPNGTLQRVVYDCP-ISISPTI---PFQFSTT--PPATASTE--NKI--T
SKTPTYHFPA---------------------------------LSYK-VCLSL-------
-------TSAFSKK---QTIFSLNLS---VT-----------------------------
------------------------------------------------------------
----------SSPTTSVCVHE---------------------------------------
-----------------------------------------------------------V
CQWSEWYDGSPLIPGFDGGDFETFSDLRAKGYEVCRAPK---AVQCRAEKFPNIPLKELG
QSVECNTKAGLICYNRDQIS--T-MCYNYEIRILCCVFV--PCSSTSSITTHSPVP----
--------------------E---------MTTTT----------------------S-S
TI----------------------------------------------------------
-------------------TTT----------------------------S---------
S-------------TT--TATGTPT--------VT---S----------TSSETASTSPE
------------TINTTP-CQPKCKWSKWYDVHFPTLH-NKGDYETYQDIRSAG-KAICR
NP---EKIQCRAEKYPHKSIEEIGQ-V-VHCNVTYG-LICRNEDQ---------------
------------------------------------------------------------
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----AGVGQRPACV--------SQPCT---GPHMFL-------------ALRAQHL---A
LPTSPV-PTGH----SLPRVTVIPPLITIP---VRALNPAHTGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 284)

CST-WGDFHYKTFDG
AVFRFPGLCNYVFSSHCGAAYEDFNVQLRRGRTSNGT-LPSRVIMKLNGMVVELTRDSVL
VNG---------HPVQLPFSQAGVLIEHSSGYLKVVARLGLVFV-WN-LD---GSLT---
----LELDTRYVNKTCGLCGDFNGIAEASEF---------LSP

ENSGT00760000118896_5_Linker_0_4 (284, 335)

NARLTPLEFGNLQKMDG
PTEQCQDPSPAP-Q-NCS-NS---------T-GI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEELLSSQLFAGCAALVNVSSYIEAC
WQDLCHCESA---H--LHDCLCHTLAEFSRQCAHAGGQPPDWRSPNL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CA--PM

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CSSGMRH
QECGSPCTD-----TCSNPQRSQLCEEHCVAGCFCPG---G---------TVLDDVRHT-
---GCVPVSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACVYNGTPYAPGANYSTDCAD-TCVGGHWSCRELPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGAHFS
TFDEKQYTVHGDCSYVLT-KLCDSSAFAVLAELRRCGLTDSETCLKSVTLSLGGGQTV-V
VVKTSGEVFVNQIY--TQLPVSAANVTILKPSTFFIIVETKL-GLQLHVQLVP-TMQLFV
RLAPELQGQTC-----GLCGNFNHNQADDFRTISGVVEGTGT-AFA------NTWKTQAS
CPNAKTSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSLLT-DVNSPFAQCHAAVSPSSYHSNCVFDTCNCERSEDCLCAALSSY
VHACAAKGVLLRGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCMKPTTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMAYQEHLGTCQPTCRSLSE-ADVTCGVSFV
PVDGCTCPAGTFLDEAGACVPAHE

ENSGT00760000118896_5_Linker_15_17 (1525, 1581)

CPCYHGGSMVPNGESIHDSGALCTCTRGVLTCIGGS
AP-SP---VCDTPMVYFDCR

PF01826 // ENSGT00760000118896_5_Domain_17 (1581, 1638)

NTTLVATGAG-CQKSCHTLD---MAC--YSTQCVSGCICP
PGLVADGDGGCVA-EEDCPCVHNEASYRSGETILDGCNT-------C----TCENRMWQC
TEEPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CAVYGDGHFLTFDGQRYTFNGACEYTLVQD--QCGGNSSALDTFRVVTENVP
CGTTGTTCSKDIKIFLG-----------------------------------SSELKLSS
GKVEVVQMG-ARQEPPYTVRQMGIYLAVDTDTGLELLWDRKTSLFLRLSPKFKGRVCGLC
GNFDGNAINDLTTR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SQAVVSDA-------LEFGNSWKFSPTCPDAPAPKDPCTANPYRKG
WAQR

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIINSAIFAACHA--HVEPAKYYEACVSDACACDSGGDCECFCTAVAAYAQTCH
EVGVCVSWR-TPDICPLFCDYYNLPGECEWHYEPCGAPCLRTCRNPSGRCLQDLRGLE--
--GCYPKCPLGAP--IFDEDKMQCVA--ECLN---PTPVPHCHIQGKS------YRV-GA
MVPSGENCHSCI--------CTE-SGVHCT---------CFCTYNGQRFWPGAEIYHTTD
GMDGCLSASCGVNGTIERRVYSCSSRSTA--P---PTTFIFS--TAPVGKSST-M-----
---PSATHTS--------------AG---------------ETL----------------
----------------------------VVAS----------------------------
------------------------------------------------------------
----------TDCGKEASSA----------------------------------------
----------------------------------------------------------PE
CV

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWLDISRPGRGIDSGDFDTLENLRAHGHELCQVPM---EVQCRAEDVPEVPLSVLG
QRVECSPTVGLTCHNRDQMS--G-LCDNYQVRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2906)

CCHPVP--CSVSSGPTAPSSALVTIT
------------------------------------------------------------
----GPATIP--------------------------------------------------
----------------RASSA--------------------------PAPGSPTPERA--
M--------P--------------------------STS--------------S------
---------MKAEPTTLSC-SKQCS

PF13330 // ENSGT00760000118896_5_Domain_29 (2906, 3007)

WTEWIDSSYPAPGRDSGDFDTLVELRGHG-YKFCE
RP---QSVECRAQFFPNTPLAELGQ-K-VTCNPEVG-LLCLNREQL----PPICYN---Y
-QIRIECCEVPHSCKMTASTSETSATP---------------------------------
------------------------------------------------------------
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---------------------------QGH------------------------------
------------------------E--------------Y--------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------QASTSTQAV---------------------------
------------------------------------------------------------
---------------------Q--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------T----PGTHTVTLPGTTGCQPQC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

TWTPWLDVDS
PEPGPHGGDLETYSHILQRGHSICRQP-EEVTRLQCRAQGHPEVPI---TILGQVVQCDI
EVGLVCHNSDQQGPEGLCL---DYEVRVLCCHMPDGCSTLGGTTRGTRTTSSI-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------RTGTS-------------L-----------------TP------------
------------------------------------------------------------
------------------------------------------------------------
-------------S----------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------TMTTTSCWLAC-R----GYL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--FPVGLTIYH------QRD--------LDGHCYHALCSWDCHVIRGVDPTCPPLTTAPT
PT------P---PV----------------------------------------------
------------------------------------------TPTSSSDACLNVVPQRKK
DETWEMPNCSQATCKGDN-IVSLSPRLCPELTPPLCANGYPALKVADAD-GCC-KHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9905)

CSGWGDPHYITFDGTYYTFLDDCTYVLVQQIVPVFGHFRVL
VDNDFCDVE---D-RVSCPQSIIVEYHGDRVVLTRR-L-VGGAMTNQILFNGEVVSPGFQ
KNGIAVSRVGIK-MYVSIRELGVQVMFSGLIFSVEVPFSKFANNTEGQCGTCTNDKKDEC
RMPG

ENSGT00760000118896_5_Linker_56_57 (9905, 9981)

GALATSCSEMSRHWRVDT----PQQAFCRGPPPTPTSAPL----------------
----GP---SSTLCPSS-PI

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10055)

CE--LI-------LSKVFELCHSVIEPLPFFEGCVFDHCH
ET---EVEVVCSGLELYASLCAAEGVCVDWRAHTNDSCRDSLYVPRTPPTRHPDPPCGDR
--------A-----HTKPPSPRALPEASRITEGCFCPDNLKLFSDKDCPIN---------
---LKAHVSSPQPGQVISKDCQECVCDPLTKSMTCQQKACP---PPPACHTPGFVSVSTL
PRAGQCCPQYSCVCNSSYCP-KL-QACPRGSHPVLIHEEGACCPSQNCSW--VACSINGT
------LYQPGAVVSSS--LCETCRCEVPSGPKWNSFVVSCETKICN-THCPMGFGYQPR
HGQCCGECIQKACRWVPGRLTLPSGSFQPG----ESWSDP-GNPCVQHTCERFQDQLEVV
TV--KRECPPLSCP-----RAQAQLSQDGCCLLCP-Q--VPTVQP--QEWPCTLRHREQV
LQHQNCSSATPVRLAYCEGICGESTSKYSLEANAVEHRCRCCQEQRTSSRTVTLRCADGS
TRAFSYTQVEECGCQGLQCQAPTSREAESG-ESQ--------------------------
-----------

------MGGKRGGPLWIFCLIWS--YCEG-------------------------------
-----------------------------KTPVQIVQRPAVTRNE

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 281)

CST-WGKFHFQTFDH
VKFDFPGICQYVFASHCNDSYQDFNIQVRRRDKSGFP---VCFTATIDGVLLEVKESGIT
VNGNE---------IPLPFSLKSILIEDTCTYFQVTSTLGLTLK-WN-WA---DTLL---
----LDLEDTYKGKTCGLCGNYDGDEKNDL----------

ENSGT00760000118896_5_Linker_0_4 (281, 329)

HLNGYKLLPRQFGNLHKVEE
PTEKCPDVAEDEDAKSYIGHSHQQKNKC

PF08742 // ENSGT00760000118896_5_Domain_4 (329, 408)

SKYKSKCKQLL--SRLGNCPKVVAFDDYVATC
TEDMCLCAKNSSDLSLASSCICSTLSQYSRDCVLNGGIPGKWRTKEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CF--QE

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPNNLEY
TECGNPCAD-----TCANPERSKICKAPCTDGCFCPA---G---------TILDDMNGN-
---KCIPNDS

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCMFQGKIYAIGGAYSTPSQNCTCAGGQWVCVSRPLSGN

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSIKGGFHVS
TFDNKEFIFHGNCHYVLA-K-DVGSRFVVAGEIIQCGVSSTMTCLKNVLVTLGA--L-NI
RLCSCGNVYINNFI--AVLPITRGGITIFRPSTFYINIMTSL-GVQVQVQIKP-IMQLFI
TVDASYQNHT-----SGLCGNFNNIQNDDFRTISGVVEDSAS-AFG------NSWKTRGS
CPDVEDNFEDPC------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------ANS
VD-KEK

PF08742 // ENSGT00760000118896_5_Domain_14 (1387, 1460)

FGKHWCELLS-NTSGVFSACHSVVDHSSYVKNCVYDTCNAEKSEEALCSVLSSY
FRDCAARGVHLQGWRP-GICDVS-KDCPETMVFSYDVKFCNHSCRSLSE-PDLLCNIPSS
PVEGCGCPKETYLHDD-KCASPEDCPCYYKDKLIQAGKSFQEGKLMCKCIRGRLDCIGET
VI-MK---DCPAPMYYFDCSSAGLGAI

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GSE-CQKSCKTQD---MQC--YVTECISGCMCP
NGLVSDGKGGCIS-ENQCPCVHGGNFYNPGENITVHCNT-------C----TCNNRQWNC
TENPCQGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1874)

CTVYGNGHYLSFDGENFDFMGDCDYILAQD--FCP-SNPNDGTFRIVTQNNA
CGKSLSICSLKITVILE-----------------------------------NTEIRLLE
GKIQEITTE-PDAVKNYKLDLRGVYIVIETSQGMTFMWDQKTTVIVLVAPSFQGKVCGLC
GDFDGRSKNDFTS

ENSGT00760000118896_5_Linker_20_26 (1874, 1923)

RGLSVEMRV-------QEFGNSWKVTSSCSNI-NTTDPCADQPFKSV
LG

PF08742 // ENSGT00760000118896_5_Domain_26 (1923, 1996)

QKHCSIIKSDLFGACHS--KINPMPYYESCVSDFCGCDSVGDCECFCTSVAAYSRSCN
RIGVCIDWR-SPRICPVFCDYYNPPDKHEWFYRPCGAPCLKTCKNPQGKCGNPLYSLE--
--GCYPECSPEKP--YYDEEQRECVSLLDCLS---------CDT----------------
------------------------KEKLCTEDSK----DCLCCYQEKTYALNETIYSQTD
GV-SCWKAVCGPNATIIRTFIPCGTSPTMV-P----------------------------
------------------------------------------------------------
------------------------AL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------EE---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------P-------------------------GLR
-----------------------------------------------NI-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----I-------------------------------------------------------
------------------------------------------------------------
----------------------------------------E-------------------
------------------------------------------------------------
------APFTA-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------ATRAS------PC---------------------
------------------------------YCKV--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------N----------------------------------------------
-------------------------------------G---Q------------------
------------------------------------------------------------
-------L----------------------------------------------------
------------------------------------------------------------
----------------------------------------------IS------Q-----
------------------------------------------------------G-----
------------------------------------------------------------
------------------------------------------------------------
---SIISQ----------------------------------------------------
------------------------------------------------------------
-TT---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------DG----------------L---------------------DQCFYS------
-------------------------------IC-------NASCQ---------------
------------------------------------------------------------
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------------------------------------------------------------
-----------------------------------------------SEL----------
------------------------------------------------------------
-------------IQGKCAT-------------------T--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------PRQS------------T-------G-----------------
------------------------------------------------------------
------------------------------------------------SEQPSY------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------QCDSAS----------------------------------------------
--------------RSGRCKNT--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PT------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------S---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------A-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------TNTST----------------------------------------------
------------------------------------------PKVTPERDCPYLNPPRKF
NETWDFGNCQIATCLGDGNDIKLSSVNCPPQRLSLCVNGFPLTKHYDK-TGCC-EVFECQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9905)

CSGWGNEHYVTFDGTYYNFQGNCTYLLVKPIQPDSQSFWIH
MDNYYCGTS---D-GAICSKSLVIFYKNSMVILTQ-AV-EHRKETNLVLFNNKKVVPNVS
KNGIKITSSG-LYVVVEIPELELYVSYGRLVFYIKLPFRTFYNNTLGQCGTCTNQKSDDA
MKRN

ENSGT00760000118896_5_Linker_56_57 (9905, 9978)

GEIADSFREMALDWRVPD----PTNRHCELNNPVPVQTE-----------------
--TSLS---KVEACVPS

PF08742 // ENSGT00760000118896_5_Domain_57 (9978, 10054)

-ALCK--LI---------WNLTGCHNAVPPQPYYEACVVDGCS
AMKKHSPKMECQSLQIYAALCGFHGICVDWRNQTNGQCEAK--CSQDQIY----KSCGGT
ERSTCFSRWVINQALR------AKADISRKAERSQNPNGMCPFHSHAGVCL-SII-----
-GCIGPDGSVKQPGETWEHDCLHCTCNQATLNISCSPHSCASTL-PVSCNKEGFVPKTRP
HSEDPCCPETVCECDVKSCS-LIPRQCDLGFQPVVAISEDGCCPVFSCIP-KSVCVSGGV
------EYKPGAVVPKN--SCEDCLCTEKQGSATQTNQIQCTPVKCS-TDCQQGFRYIRE
EGKCCGQCVQTACVARIPSG---IVTVEVG----KTYRVL-GGNCTLHNCTQSSGQFVLT
ST--IISCPEFDPSNCV--PGTVATSSDGCCKTCI-P--LS--------HVCKLKLKKEF
ITHKNCKSASPVLVPSCEGSCST-YSVYAFDDSKMKHKCMCCQETKSHTMKVELVCAKRK
RLTYTYVHVDECDCVEIKCSEKKP------------------------------------
-----------

----MGVGRRKLVPLWVLALALA--CGQHTGQAQQDS----LKSDHP------FVP---A
VPC----------------------LQSLPLLWSTALNPAHTGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 268)

CST-WGDFHYKTFDG
QVFRFPGLCNYVFSAHCGVAYEDFNIQLRRARESNST-TLSRVTMKLDGLVVELTKSSVL
VNN---------HPVQLPFSQSGVLIELSSGYLKVVARLGLVFM-WN-DD---DSLL---
----LELDTKYANKTCGLCGDFNGSPE

ENSGT00760000118896_5_Linker_0_4 (268, 335)

SSEF---------LSHNVRLTPLEFGNLQKMDG
PTEQCHDPLPVP-QKNCS-TR---------S-SI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEEILKGQLFSDCSALVDVSSYLEAC
HQDLCLCESP---D--LTSCICHTLAEYSRQCAHAGGQPQDWRGPNL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CS--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCVD-----TCSNPQRSQACEDHCVSGCFCPK---G---------MVLDDINQT-
---GCVPVSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACLYNGTSYAPGTNYSTDCTN-TCSGGRWSCQEVPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGSHFS
TFDERQYTVHGDCSYVLS-KPCDSNIFTVLAELRKCGLTDSETCLKSVTLSLGGGQTV-V
MVKATGEVFVNQIY--TQLPVSTANVTLFRPSTFFIIAQTNL-GLQLEVQLVP-IMQVFV
RLAPELRGLTC-----GLCGNFNSIQADDFQTISGVVEGTAA-AFF------NTFKTQAA
CPNVRNIFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSQLT-DASGPFSQCHTTVNPSTYFSNCMFDTCNCEKSEDCMCAALSSY
VHACAAKGVLLSGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKATTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYQYHISTCQPTCRALNE-EDVTCHVNFV
PVDGCTCPAGTFLDDSGKCVQATS

ENSGT00760000118896_5_Linker_15_17 (1525, 1586)

CPCYHRGSTVPNGESVHDSGAICTCTQGTLTCIGGP
AP-TP---VCDAPMIYFDCRNATPG

PF01826 // ENSGT00760000118896_5_Domain_17 (1586, 1638)

DTGAG-CQKSCHTLD---MTC--YNSECVPGCVCP
DGLVADGNGGCIV-AEDCPCVHNEATYRPGDTIRVGCNN-------W----YA----WMT
A-SPVAAT-----------TTGTHRPSLVPNDLLF

PF00094 // ENSGT00760000118896_5_Domain_20 (1716, 1876)

LQD--NCGGNGSSQDAFRVVTENIP
CGTTGTTCSKDIKIFLG-----------------------------------NYELKLSD
GKVEVVQKG-VGQEPPYYVHQMGIYLVVETDVGLVLLWDRKTSILLRLSPEFKGKVCGLC
GNFDDNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVGDM-------LEFGNSWKFSPSCPDALVPKDPCSANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIINSETFTACHA--HVEPTKYYEACVSDACACDSGGDCECFCTAVAAYAQACH
EVGVCLSWR-TPDICPLFCDYYNPEGQCEWHYQPCGAPCMRTCQNPSGHCLHDLHGLE--
--GCYPKCPPTAP--IFDESTMQCVS--NCTAVPSPPPPRPCRINGKL------YRP-GA
KVPSDKNCYSCI--------CKE-NGVSCSHDAS----ACVCTYNGQHFHPGDIIYHTTD
GTGGCISAYCRANGTIERNVDTCSSTTPM--P---PTTFSFS--TP------VVM----T
SMAPSSTYPS--------------SA---------------PSVVY----TGSPGTAA--
------WTTSSMVSVKTPAT-ASTLT--PSAM----------------------------
------------------------------------------------------------
----------ASTATMLGCQ----------------------------------------
----------------------------------------------------------EE
CV

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWMDVSRPGRGIDSGDFDTLENLRAHGYHICQAPR---AVECRAEDTPEVPLHAIG
QRVECSTTVGLTCHNRDQVS--E-LCDNYQIRIQ

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCTPIS--CPT-------TQLITSRT
TTK--------------GPK--T-SVAPVTSTD------------------L-AD-ST-V
IS--GPSTHAPRPL----------------------------------------------
-----------PSSSHPSSSA--------------------------SSPSPPATVSS--
T--------TVK--TT--LSTTSPIP--EP----TSATS--------------SVSIATS
GST------IASLETTHECKREVC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

NWTDWIDGSYPGPDRNSGDFDTFANLRSKG-YKFCE
KP---QNVECRAQFFPNTPLEELGQ-D-VTCNRDEG-LICLNKNQL----PPICYN---Y
-EIRIECCTIVDTCSTASTTTHP-TSHE--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------VS---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------TETK

PF13330 // ENSGT00760000118896_5_Domain_41 (5871, 7290)

TTW-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------TTSSHSSSS---------------------------
------------------------------------------------------------
---------------------KD--------T---------------------STLS---
------------------------------------------------------------
--------------------------------------------ATIHTRNR--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------AT-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------DSPHTISTPVTTHCQPQCTWTQWFDTDF
PD----------------------------------------------------------
-------------TSGMCL---NYEVRVLCCRLPEGCPVTPGPLPVTSSHKPSF------
------------------------------------------------------------
------------------PI----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------V--
STSSVPPSS-LSSPW-------------VH------SA--------IP------------
------------------------------------------------------------
------------------------------------------------------------
-------CLCNVSG----L------------LYPIGSI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------IY-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------N------RTD--------LDGHCYYALCSQDCQVVRGVSQDCPSTMPPPT
PAL--STSA---ST----------------------------------------------
------------------------------------------VTPVTERDTCNVFPPRMK
GETWPMPNCSQATCEGNN-VISLSPRQCPEVKAPSCANGYPPLKVDDQD-GCC-QHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9905)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVFGHFRVL
IDNYFCDLG---D-SVSCPQSIIVEYHQDRVVLTRR-P-VGGIMTNQIIFNNKVVSPGFQ
QNGIVVSRVGIK-MYVTIQEIGVQVMFSGLIFSVEVPFNLFANNTEGQCGTCTNDQKDEC
RLPG

ENSGT00760000118896_5_Linker_56_57 (9905, 9981)

GAI-TSCSDMAPHWKV------PNQPSCQGPPPTSTSVVP----------------
----SP---SPTPCPPS-PI

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10055)

CE--LI-------LSKVFQSCHDVIPPLPFYEGCLFDYCH
GM---GWEVVCSGLELYASLCAAHGRCIPWRSQTNNTC--SFTCPANKVY----QPCGPT
NPYYCYGNDDLSTS-------LTLQEAGPFTEGCFCPDDMTLFSTNDSICV-PS-CQWCL
GP----HGEPVEPGHTISFDCQDCICKEATL--TCQRKRCP---Q-TTCPEPGFVPVPEA
LEAGQCCPQFSCVCNSSHCP-PPLH-CPENSSLMVTYKEGACCPSQNCS--RKG

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CEFNRT
------LYQPGDVVSSS--LCETCVCQAPSNPHSDVFVISCETELCN-TLCPTGFEYQAK
PGQCCGRCVQKGCTFK-NSNSW--ASFQPG----ESWSES-GDPCVTHKCEQLQDVFIVV
TT--KRECPKVNCP-----QGQVQLREDGCCHDC---------------LKCTVHQRQQI
IRQQNCSSEGPVSLSYCQGNCGDSTSMYSLEANAVEHKCECCQELQTSQRTVTLHCDDGS
SRTYSYTQVEKCGCLGQRCHALGDTSYSESSESEFRPKESKEHGQLSASGASKEVPGPSQ
-----------

----MGTGRGARIPLWIPILVIALTHSKVKGQAEYPNQYEDQQTQYEDQQYSQQQEYYDD
LSF-----VQPTHDQPQSQVTIIPPVKTTL--AVKAINPPHNGRL

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGNFHYKTYDG
NIYNFPGLCNYVFTSHCKSSYEDFNIQIRRKVVDKVP-TIEHIFMKLDGTGIELTPNTIT
VNGEH---------VQPPYSYSGILIEEISGYKTVTSKLGVFLT-WN-QQ---DALL---
----VELDEKYMNQTCGLCGDFNGI

ENSGT00760000118896_5_Linker_0_4 (266, 331)

TTYNEF---------ISNGIILNPVQFGNLQKLDG
PTEQCQDPLPSA-PSNCSSEF---------

PF08742 // ENSGT00760000118896_5_Domain_4 (331, 409)

-NSVCETILTGEAFLGCNALVAMEDYADAC
VHDLCNCEKS---E--TDACMCDTFAEYSRQCAHAGGQPLEWRSEGLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

A--KS

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMEH
KECGSPCSD-----TCTNPERSQVCEDHCRDGCFCPA---G---------TVYDDINNS-
---GCIPLED

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTYNGDTYAPGASFASQCSSCQCTGGQWTCVSQSCPGI

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSIQGGSHIT
TFDGKQYSVFGDCSYVLT-KLCDSDLFTVLGEIRKCGMTDTETCMKGVVISMNHGET-VI
AIKSTGDVFVNSMA--TQLPFSASNITMFKPSTFFIVAKTNK-VFRIEIQLVP-LLQTTI
YVDPVHKEMTC-----GLCGNFNDAQADDFKAISGVVEGTSA-AFA------NTWKTQAA
CPDIKNIFENP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CALS
IE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

KYASHWCRLLT-DSNGPFQKCHSVVDPAVYHKICMHDTCNCEKSEDCLCAALSSY
VRACASKGVKLTGWRT-SV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CTKYQ-I

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPETLTYHYEIETCQPTCRSLST-PDVTCNIQFT
TVDGCTCEEGTFLDESGKCVPPTSCPCYYKGSPILSGEVFRENGMMCTCTKGKLECIGEV
RP-QP--AVCNAPMIYFDCQNATIGVTGAE-CQKSCQTLD---MGC--YSTQCVSGCMCP
NELIYDGKGGCVA-AEECPCTHNEATYNPGETIKVKCNT-------C----TCKNRKWEC
SDELCLET

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CSVYGDGHYVTFDGKRYSFGGECEYTLVQN--HCGKNS--TGTFRVITENVP
CGTTGNTCAKSINVYLE-----------------------------------DYELKLAD
EKFQVIQRTPGSSEVPFKIRKLGNFYVADTTEGVVIVWNMKNSVSIKITPAYRGQVCGLC
GNFDGNDANDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1920)

QSVVTDV-------VEFGNSWKVSPTCPGTPQTKDPCTANPYRM

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1996)

S
WSQKQCSIINSQTFAPCHS--QVEPTKYYDACVSDACACDTGGDCECFCTAVAAYAQACS
EAGACISWR-TPDICPIFCDYYNPKGECEWHYQPCGAACQKTCRNPEGKCIHELQGLE--
--GCYPKCPKDKP--YFDEDEMKCVPRDQCGCF------DD---KGNH------YKP-GE
QIPSEKNCESCQ--------CSMGSQAICAHDEN----ACYCLYDGKKHMPGDIIYKTTD
GIGGCIIATCSHNGTIERDIFQCETTTTVATPTT-VFVFTST--SQPTTTTG--KSS--N
D---SFFIKRYQ------------------------------------------------
-------SSKFLR---IAGSFYTTDL---SSS----------------------------
------------------------------------------------------------
----------TAPTTTLCVQE---------------------------------------
-----------------------------------------------------------N
CHWSQWYDVSQPGSGEDDGDFESFDHLRAHGYEICKAPK---KVECRAEKFPNTPISELD
QKVECNTEVGLICYNKDQNT--T-ECHNYQIRIQCCSFV--PCGYTTASTSKTTTVSTAP
TVTTMLSTAKSTSTTSISTTESTTTTTAPTTSTTAETTT-VTITPSTTKST-TTILTK-S
ASTPEPTTVTTTPS----------------------------------------------
-----------TTESTTTTTAPTTSTATPETTTGACYAVRNPECPPTPIPSTTTSHPVPT
TTTKVVTTTTLETTTTAATTTTTPTTTTSSTKVTTAATTT-RASTPKSTREHTTTLPTTT
SLPTTSTIQVTTTSPKTPCSPMKCQWSQWFDTHYPTSEPQGGDIETYNNIRAAG-GKICE
KP---SNIQCRAESLPEVPISELGQ-V-VECDVNKG-LVCENNKQS--GKNQQCNN---Y
-EMRVLCCEENPECHPHTKVVTTTTRPV----TTT-----TI--ET-T-------T----
---TA-----------ATT---------------------TT-----PTTTTS-------
-STKVTTA--A-------------------------------------------------
---TTTRA------------STPKST-----------REH------TTALPTTTSL----
---------P-------TTSTIQVTT---------------TSPKTPCSPMKCQWS-QWF
DTHYPTSEPQGGDIETYNNIRA-AGGKICEKP----SNIQCRAESLPEV-PISELGQVVE
-CDVNKGLVCENNKQSGKNQQCNNYEMRVLCCEENPECPPTPIPSTTTSHPVPTTTTKV-
----------------------------------------------V-------------
------------------------------------------------------------
------------------------------------------------------------
------------------TTTTLETT----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
TT--AAT--TT------------------------------TTPTTTT------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------S------------------------------
----STKPTTSTI-----------------------------------------------
-----------------------------------------QVTTTSPKTPCSPMKCQWS
QWFDTHYPTSEPQGGDIETYNNIRAAGGKICEKPSNIQCRAESLPE-VPISE---LGQVV
ECDVNKGLVCENNKQSGKNQQCNNY-EMRVLCCE-EN-PECPPT--------PIPSTTT-
------------------------------------------------------------
------------------------------------------------------------
----S-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------H-----------
----------------------------------------------------------PV
PTTTTKVVTT---TTLETTT----------------------------TAA--------T
TTTTPTTTTSSTKVT-------------TA--ATTTRA---------STPKSTREHT---
-----------------------------------------------------------T
-T-----L----------------------------------------------------
------------------------------------------------------------
----------------------------------------------LTTTSLLTT-----
----------------------------------------------ST------------
------------------------------------------------------------
------------------------IQVD--------------------------------
---NNISK--------------NTLAPPHENA----------------------------
----------------SGPS----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-GLILTIPPSEP-QGGDIETMPAGRK-------KSGDKPVNIQCR-AEDQPEVPIAELGQ
VVDCD-----------VNKGLVCMNEEQTGKHKQCNNYEMRVLCCEE-------------
-----NPECPPTPIPSTTTSHP-----------V--------------------------
------------------------------------------------------------
----------PTTTTK-------VVTT---------------------------------
-----------------------T------------------------------------
------------------------------------------------------------
-------------------------------SRPVTTTT---------LETT--------
--------------------------------------T----------------T----
------------------------AATTTTTPT---------------------------
------------------------------------------------------------
------------------------------------TT------TSRTKVTT------AA
TTTRASTPK---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------S---------------TRE
HTTTLPT-----------------------------------------------------
-----------------------T------------------------------------
--TSL-----------------PTT------STIQVTTTSPKTPCSPMKCQWSQWFDTHY
PTSEPQGGDIETYNNIRAAGGKICEKP----SNIQCRAESLPEVPI---SELGQVVECDV
NKGLVCENNKQSGKNQQCN---NYEMRVLCCEENPECPPTPIPSTTTSHPVPTT------
-----------------------------------------TTKVVTTT------TL---
-----ETTTTA-------------------ATT---------------------------
------------------------------------------------------------
-------------T--TTPTTTTSSTKVTTA------------ATTT-------------
------------------------------------------------------------
-----------------------RASTPKSTR----------------------------
----------------------------------------------EHTTTLPT------
------------------------------------------------------------
---TTSLPT---------------------------TS--------TIQVTTTS------
------------------------------------------------------------
-----------------------PKTPCSPMKCQWSQWFDTHYPTSE---PQGGDIETYN
NIRAAGGKICEKPS----NIQCRAESLPEVPISELGQVVECDVNKGLVCENNKQSGKNQQ
CNNYEMRVLCCEENPECPPTPKPSTTTSKPVPTTTT------------------------
-----TVAPTTTTRPVTTTTLEITTAATTTTT---------------------ASTIVTA
AATTRPSTPKSTME---H----------TTTLPTTT----------SLPTTSTT----TI
TTTIKPTSPTTTAELSTTS-----------------------------------------
-----------II-----------------------------------------------
-TEVPTPTSS-------------------------------------------ASSTTQC
FCKIGEKT---YRPGETIYNRTDSDGCSFYAVCDLKCSVE--RSKGPCPATSPRPTP---
TVVITTPTTTPVSTTQPIGCPD--------------------AIPPREVRTA--------
SYIGVG-----------------------ELDMSPTPKSKPQHFPDEK--IAPLF-----
------SVHEWSI-------------------------------KKFILGCHFQDTSLCT
Y-----------------------------------MQ--IQIFQNLKKSKTLLVPSISD
KVAYTVSSTSIVNDILCLFQS-----WNMKDAYV---------------------ETAVV
KCLKQNRSFPKSLYCLLIYSSNI-----HK-MTLLHSS-------IWQEGLELNGC----
-------VVKVRSMEPCTDGRSMQLKQHAVIEFLTAEGVTPKEKGVTFILVMGDEFLANF
KSVHFHFKHQHPGYSSCTDLPIA--------KQSNNVTHTFLNFSLSDMTIILNQSVNLL
LVKLSGGCHRTSNS----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SF--------
------------------VTQV------------RCS-HLN-IFKLTRPRRT-VLTSTIS
FGV---TPSAVKNSMTAHCLRFHNINDIRICY----------------------------
------------------------------------------------------------
------------------------------------------------------------
--YWTGDCWIRLTKMLRKAYGKHKRYKPYLGTHIFVLFQYNSNVRENS-IRSELRSTPCM
PQKRKIDARKCSMA----------------------------------------------
------------------------------------------GVVYKMHTTNELKPKTQV
GETWT-SNCTRYTCEGNN-KIAVSHVKCPKVQDIVCENGYPPVKVFQD-DGCC-YHYECE
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9905)

CSGWGDPHYITFDGVYYTFVQNCTYVLVKEITPKHDNISIL
VDNAYCDSK---D-ELSCPRSIIINYKSSEVILTR-EN-VDGVEANKIYFNGKAVSPGYH
HDDIYISSNG-INMVAEMPKIGSQVSFSGLIFFIKLPPS-FVNNTEGQCGTCTNDKKDEC
RLPN

ENSGT00760000118896_5_Linker_56_57 (9905, 9976)

GEIASSCSHMAPYWRVHD----EKKEYCAGPIPTPAP-------------------
----TE---TPTPCP

PF08742 // ENSGT00760000118896_5_Domain_57 (9976, 10054)

PN-ELCK--II-------LHDVFSECHDIIPPESYYKGCLFDACH
QT---NTSVQCSGLEIYGSLCASKGVCVDWRSSTKGECSYN--CPAGKIY----DPCGPL
NPLTCEFGDDYLNSVS---MGALHHNGSGITEGCFCPEGTQLYNEHSDTCV-SECVS---
PGCIGPDGQPKAPGSTWISNCQECTCEKYSRRVRCKPKACEASPTPVHCQLEGFIPVQVM
TPEDKCCPETQCVCNTSYCT-ETIKSCPVGYTLKQQNLPGDCCIHTTCVK-LPGCVVDGN
------LYQPGARIPG--DICESCTCSLEENPETKSNEVECVSQVCH-TSCSVGQEYKEV
PGQCCGNCTAVACVLKQEPY--GSQAIKPG----ERLHPP-GDNCTFYECDLIDGQYVLV
TT--KKTCSGFDPTTC--KPEDVIKTDDGCCETCR-L--PL--SQYQNMTICGPKSTRSV
IKYKGCEASSPVELTYCEGQCGS-SSIYSYKANTMNHSCSCCKELRTTEKQVTLTCADGS
TLDYSYIYIDECDCIGNEC-----------------------------------------
-----------

----MGVGQRKLAPLWTLALALA--CTQHTGHAQDSS----SESSYG------HHP---A
LSPVARGPSGV----PLRGVTLFPPLRTTP--VVRASNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGNFHYKTFDG
DVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAP-TLSRVLMKVDGVVIQLTKGSVL
VNG---------RPVLLPFSQAGVFIQQSSSYTKVEARLGLVLV-WN-HD---DSLL---
----LELDAKYANKTCGLCGDFNGM

ENSGT00760000118896_5_Linker_0_4 (266, 335)

PVVRE-L--------LSHNIKLTPMEFGNLQKMDD
PTEQCEDPVPEP-PRNCS--T---------GFGI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEELLNGQLFSSCVALVDVGSYLEAC
RQDLCFCGGT---D--LLSCVCHTLAEYSRQCAHAGGLPQDWRGPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPSNMQY
HECRSPCTD-----TCSNQEHSRACEDHCVAGCFCPE---G---------TVLDDVGQM-
---GCVPASQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACVYNGAAYAPGATYSTDCANCTCSGGRWSCQEVPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGAHFS
TFDERHYTVHGDCSYVLT-KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV-V
VIKASGEVFLNQIY--TQLPVSAANVTIFRPSTFFIIAQTSL-GLQLDLQLVP-TMQLFV
RLAPKLRGQTC-----GLCGNFNSIQADDFRTLSGVVEATAA-AFF------NTFKTQAA
CPNIRNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1458)

WCSQLT-DANGPFSRCHTAVKPDTYYSNCMFDTCNCERSEDCLCAVLSSY
VHACAAKGVQLSGWRN-

ENSGT00760000118896_5_Linker_14_15 (1458, 1467)

GVCTKPMTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYHYHVSTCQPTCRSLSE-GDITCSVGFI
PVDGCICPEGTFLDDTGKCVQASNCPCYHRGSVIPNGESVHDSGAVCTCTHGKLSCIGGQ
AP-TP---GPVP-------------------CPITQWCLL---ALQ--YSPQCVPGCVCP
DGLVADGEGGCIT-VEDCPCVHNEASYRAGQTIRVGCNT-------C----TCDSRMWRC
TDNPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CAVYGDGHYLTFDGQSYSFNGDCEYMLVQN--HCGGKGSAQDSFRVVTENVP
CGTTGNTCSKAIKIFLG-----------------------------------GSELKLSH
GKVEVIGTD-ESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPKFKSRVCGLC
GNFDDIAVNDFATRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVGDE-------LEFGNSWKLSPSCPDALAAKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFATCHA--HVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACH
EVGLCVSWR-TPSICPLFCDYYSPEGQCEWHYQPCGAPCLRTCRNPRGDCLQDIWGLE--
--GCYPKCPPEAP--IFDEDKMQCVA--TCPT---PSPPPLCHVHGKS------YRP-GS
VVPSDKNCHSCL--------CTE-RGVECSYEAE----ACVCTYDGQRFHPGDVIYHTTD
GTGGCISARCGANGTIERRVYPCSPTTPV--P---PTTFSFS--TPPLVVSSTHAPSPVP
----SSVHT------------------------------------------GPPSSAWP-
------TTAGT-----------SPRT--RSPT----------------------------
------------------------------------------------------------
----------ASASLPPVCG----------------------------------------
----------------------------------------------------------EE
CL

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWMDVSRPGRGMDSGDFDTLENLRVHGYLVCESPR---SVECRAEDAPRVPLRALG
QRVQCSLDMGLTCRNREQAS--G-LCYNYQIRVM

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCTPLA--CSTSSSSTQTTPPTTSKT
TET--------------RAS--A--SSVPS------------------------------
----------STPG----------------------------------------------
-----------PVSLSTSRTT--------------------------PAPGTAT------
---------SVK--KT--FSTPSPPP--VP----AASTSS----M-------STTAPGTS
VVS---SKSIHTESITPSCVHELC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

TWTEWIDGSYPDPGINGGDFDTFQNLRDEG-YKFCE
NP---RSVECRAQAFPNTPLADLGQ-D-VICSRTEG-LICLNKNQL----PPICYN---Y
-EIRIQ

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCKTVNTCRDGTRTLKTVTTTRPT---PHPAGAQ--------------------
------------------TQTTFTTHMPSASTEQ--------------------------
------------------------------------------------------------
-------------------------P-----------TAT------SR------------
-----------------------GGSTA----TSVTQGTHSRSATTDCHP-QC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

TWT-KWF
NVDFPSPGPHGGDEETYNNIIR-SGEKICRQP-EEITGLQCRAKSHPEV-SIEHLGQVVQ
-CSREEGLVCRNQDQQGPFKTCLNYEVRVLCCETPKGCPVTSTPVTAPSTPSGRAT----
---SPTQST---------------------------SSWQK-PR----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------TTTLVTISTTSTPQTSTIS---------------TPTTSMT
SA-----------------PTPRTT-----------------------------------
------------------------------------------------------------
-------------------------------------------------------YALTT
S--TTSAPTTS-T--------------S--------SAPTTS------------------
------------------------------------------------------------
--------------------------TT------------SAL------------TKSTT
--------CTRKTS----------------------------------------------
---TTSAPTTSMTSAPT-------------------------------------------
-----------------------------------------TSTTSAPTPR---------
------------------------------------------------------------
------------------------------------------------------------
--------------------TTSAPTKS-------------------------------T
TCTRKTSTTSAPTTSTTSAPTTSMTSAPTPRTTSAPTKSTTCTRKTSTTSTPTTSKTSAS
TTSTTSAP----------------------------------------------------
------------TPRATSAPTKSTTCTRK-------------------------------
-TNTTSTPKT-STTSAPTPRT---------SAPTKSTMF---------PTTST-------
-TSAPTTSTSSA------------------------------------------------
-----------------------------------STTSTTSSPGTTLSPVPTISTNSAP
TIRITSAPTSSTTSATTISITSGPETTLSPVPTTNTTS----------------------
-------------------------------------------------APTKSTTSSPG
TTLSPVLTTSTTSAPTTS--------KTSASKTSTTSG--AG-TPPSPVPTTSTTSA---
PTT---------STSSAPTTTT-PS-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------SVPTTRTTS--------APTTSTTTAPTSSKTSA
TITSKTSGPETTHSPVPTT--------------------------------STTSAPGTT
PSPVPTTSTTSHNLCSWXXXX-----------------XXXXXXXXXXXXXSP-------
----VPTTSTT-------------SASTTS--TTSAPGTTPSPVPTTSITSSVPTIST--
----TSFAPTFSTSS--APTTSTTSSPGTTP------------STVPTTSANSASTTRTT
SAATSRTTSAATTSTTSSPETTRSPAPITTT-----------TSAPTTSTTSSPRSTPSP
VPTTSTTSAPTTSKTSASTTS---------------------------TTSS--------
----------------------P----ETTPSPVP------------------ATSTTSA
PTTSTSYA----------------------------------------------------
---PTTSTS-----------------------------SAPTN-----------------
----------------------------------------------STTSI---------
------PGTT--PSPVPTTSTTSAPTT---------------STTSAATSSTTSAAITST
TSGPETTHSPVP-TTSTTAASTTSTT-SGPGTTPSPVPTT--------------------
------------------------------------------------------------
------------N-----------------------------------------------
----------------------------------------TTSAPTTST-----------
---------------------SSA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------PTTSKTSA--------STT--------
--------------------------------------STTSSPGTTPTSVPTTSTTSA-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------STTRTT------------
-----SAP----------------------------------------------------
--------------------------------------------TSSTTSAP--------
------------------------------------------------------------
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-----------------------------------TTRTTSS---------------PGT
TPSPVPT-----------------------------------------------------
-----------------------TS---------------------T-------------
---T----------------SALTTS-KTSASTTS-------------------------
-----------------------------------------TTFGP---GTTPSPVPTTS
TTSAP-TTSTSSAPTTSTSSAPTTSTTSIPGTTPSPVPTTST----TSAPTTSTSSAP--
--------------------------------------------------TTSTTRT---
--TSPTTTSTT-----SGPGTTQ--SPVPTTST---------------------------
------------------------------------------------------------
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---------------------VSAPTTRKTSA-----PTTTVTSTTSGPE---TTPSPV-
P----------------TTSTTSAPTTST------------------------SSAPMTS
TTSSPGTIPSLVPTTSTTSAPTTSKTSASTTSTTSVAGTTPSPVPTTSTTSAPTTSPSSA
P--------TNST--T--------------------------------------------
-------------------------------------SGPGTTPSPVPTTSITSAPT---
TRTT-----------SAPT-------------SS----------------------TTSA
STTTPT------------TSTTSAPTTSTTSAPATSTT----SAPTSSTTSTAQTS----
------------------------------------------------------------
------------------------------------TTSTPTISTTS------------A
PTIST---------------------PSSPGTTPSPVPTTSTTSVSKTSTSHVSVSRTTH
-----PQSVTRDCHPQC

PF13330 // ENSGT00760000118896_5_Domain_54 (8718, 8878)

TWTK-----WFDVDFPS---------------------PGPH-
-------GGDEETYNNIIRSGEKICRQPEE-ITGLQCR----AKSHPEVSIEHLGQ----
-------VVQ------CSREEGLVCRN------QDQQGPF------KTCLNYEVRVLC--
----CEIPKGCPVTS-VTPYGTS-TN-ALYPSL---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------STSV--------
-----------------AS--------------------------TSVAS----------
-SS---VASSSVAYSTRTCFCNV-T----DRL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--YPAGSTIYR------HRD--------LAGHCYYALCSQDCQVVRGVDSDCPSTTLPPA
PAT--SPWT---ST----------------------------------------------
------------------------------------------SEPVTELGCPNAVPPRKK
GETWAMHNCSEATCEGNN-IISLRPRTCPRVEKPTCANGYPALKVTDQ-DGCC-HHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVL
VDNDFCGAE---D-GLSCPRSIILEYQQDRVVLTR-KP-VHGAMTNEIIFNDKVVSPGFR
KNGIVVSRVG-IKMYATVPALGVQVMFSGLIFSVEVPFSKFANNTEGQCGTCTNDLEDEC
RTPEG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TVVASCSEMAGLWNVST----PNQPACHGPRPLPTTVRPTTV----------GSI
TFGPTT---PPAPCPPS-SI

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CQ--LI-------LSKVFEPCHAVIPPLPFYEGCTFDQCH
KT---NPDTVCSSLELYAALCASQDICIDWRGRTNHTCPFT--CPADKVY----QPCGPS
NASYCYGNDSASL--------GALPEAGPITEGCFCPEGMTLFSTSVQVCV-PTGCPRCL
----GPHGEPVKVGHTISRDCEECTCEAATWTLTCRPKLCPLPP---ACPLPGFVPVPAA
PQAGQCCHQYNCVCNTSRCP-A-PVDCPEGARAIPTYEEGACCPVQNCNW--TECSING-
-----TLYQPGAVVS-S-SLCETCRCELPGGSLSDTFVVSCETQICN-THCPVGFEYQEQ
SGQCCGTCVQVACVANTSGS--SAHLFYPGMHLAETWSDP-GNHCVTHECEKHLDGLVVV
TT--KKACPPLSCS-----LDEARKSEDGCCHFCP-P--PPLPPQYQNQSTCAVYHRSQI
IQQQGCNSSEPVRLAYCRGNCGDSSSMYSFEGNMVEHRCQCCQELRTSLRNVTLHCADGS
SRAFSFTEVEQCGCMGRRCPAPGDTQHSEEMGSK--------QSQEAGSGSWERSTPVSP
VH---------

------------------------------------------------------------
---------------------------------------SHNGYV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 285)

CST-WGNNYFKTLDG
DIFYFPGQCNYLLASNCKSVTEEFNIQIRRSVVNGLP-TVSHIGMKIEGVFIEFTGGNIT
FNGNVFG-----TRVDLPYSFSGIQIDRSGAYIRVISKVGLEFR-WN-ED---DAAT---
----LELDQKFINQTCGLCGDFNGIPTYNEF---------MFNN

ENSGT00760000118896_5_Linker_0_4 (285, 317)

VRLTDNQYGNMQKMNG
PTETCEDVLQAP-EDK

PF08742 // ENSGT00760000118896_5_Domain_4 (317, 409)

CTDL-----------SSVCHAILKSASFVYCNNLVDPTPYINVC
VQDLCRCKRN---A--TGFCLCNTFTEYSRQCAHAGGTPSNWRTNNLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--LQ

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CSYNMEY
RECGTACPD-----TCSNPDRSLSCDRHCTDGCFCPA---G---------TVWDDINNS-
---GCIPSSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCAYNGEVYSPGSSYFAQCQSCTCLKGKWKCVNRDCSGS

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CSVIGGSHIT
SFDVTRYNFFGDCSYVLT-KKALDNQFSVVAELSKCGLKNTETCLKSIVIYLEYGND-TI
KIQHSGSVDVNTIF--SQLPVSSASVTIFKPSSFFIIVEAAA-GLQVEIQLVP-IMQVYI
YLQPMWRAQVS-----GLCGDYNNVQMDDFKVLSGVIEGTAA-SFG------NTWKTQAS
CPNVISHFDDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-N

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1461)

ANYAQFWCSKLT-DPAGPFAVCHAKVNPLLYKTNCMFDSCNYGNSQDYMCAALSAY
VHACARMGILITEWRD-TNCDSYTTNCPSTLSYSYNITTCQPTCRSLSE-PDVTCSIDFV
PVDGCICTNGTFLNEQGFCVPRESCPCYFRGTIVPSGHTITESGALCTCSMGTLNCIGQP
DI-MKGLAECKSPKVYFNCSNQPAGITGTE-CEKSCQTLD---MYC--YSAHCISGCMCP
DGFVANGTDGCIP-EYECPCMHNNNLYEDGATIRVSCKT-------C----TCQNRMWNC
NDETCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1877)

CAVYGDGHYYTFDSNRYSFSGDCQYVLAHD--YCT-NDPTNGTFRIITENIP
CGSTGTTCSKSIRFYIG-----------------------------------NNVLVLDE
GKFEVQNTGSG-ASVPYKVHQMGIFLVIETLNGIVLVWDKKTSIYIKLHPDFQGKICGLC
GNYDGNAINDYTTRSL

ENSGT00760000118896_5_Linker_20_26 (1877, 1919)

SVVADV-------LEFGNSWKQSSSCPVPVAMADSCAAHTYR

PF08742 // ENSGT00760000118896_5_Domain_26 (1919, 1996)

KP
WAEKKCSVIIGTRFAACHAVNQVNPNPYYSTCVNDACACDTGGDCECLCTAIAAYAQACS
EAGACVSWR-TPDFCPLFCDYYNHKGQCEWHYQACGAPCMKTCRNPSGNCYYNLMGLE--
--GCYPVCPPDRP--YFDEEIMECVP--SC-CY------DS---RGRN----YLFHQVMP
RMPGDAHCTICM--------CTR-HGRQCFPDYK----QGCCEYDMTTYTTSQPIYSTPD
KLGGCNYARCE-NGTIVRYTTDAPCTHTTS--------------TPVTTSIT--TTS---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------TSTITP---------------------------------------
--------------------------------------------------------DCYY
CKLTKWIDVSSPENKI-TADIKTFENIRNNNVPICESPMTIMRLDCRVKNSKLSSKHFKQ
SQKCNMQEVGPLCLNGKKS---Q-RCKKYEIQIQCCYRNQSSYLTTTHSTTTTIPETTTT
H-S---------------TTKTTT----------------------------THSTTT-T
SSPTT-------------------------------------------------------
------------------------------------------------------------
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-----------

----MGAPSACRTLVLALAAMLVVPQAETQGPVEPSW----ENA----------------
---GHTMDGGAPTSSPTRRVSFVPPVTVFP--SLSPLNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-VVTRVVIKAQGLVLEASNGSVL
INGQR---------EELPYSRTGLLVEQSGDYIKVSIRLVLTFL-WN-GE---DSAL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 339)

AFNEF---------YAHNARLTPLQFGNLQKLDG
PTEQCPDPLPLP-AGNCTDE-----------EGICHRT

PF08742 // ENSGT00760000118896_5_Domain_4 (339, 408)

LLGPAFAECHALVDSTAYLAAC
AQDLCRC------P----TCPCATFVEYSRQCAHAGGQPRNWRCPEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCTD-----TCSNPQRAQLCEDHCVDGCFCPP---G---------TVLDDITHS-
---GCLPLGQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA-I
RVQADGGVFLNSIY--TQLPLSAANITLFTPSSFFIVVQTGL-GLQLLVQLVP-LMQVFV
RLDPAHQGQMC-----GLCGNFNQNQADDFTALSGVVEATGA-AFA------NTWKAQAA
CANARNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY
VHACAAKGVQLSDWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKYMQN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQRYAYVVDACQPTCRGLSE-ADVTCSVSFV
PVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGAS
LQKST---GCAAPMVYLDCSNSSAGTPGAE-CLRSCHTLD---VGC--FSTHCVSGCVCP
PGLVSDGSGGCIA-EEDCPCVHNEATYKPGETIRVDCNT-------C----TCRNRRWEC
SHRLCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CVAYGDGHFITFDGDRYSFEGSCEYILAQD--YCGDNT-THGTFRIVTENIP
CGTTGTTCSKAIKLFVE-----------------------------------SYELILQE
GTFKAVARG-PGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLC
GNFDDNAINDFATR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SRSVVGDA-------LEFGNSWKLSPSCPDALAPKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACRS--QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH
DAGLCVSWR-TPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLE--
--GCYPKCPPSQP--FFNEDQMKCVA--QCGC---------YDKDGNY------YDV-GA
RVPTAENCQSCN--------CTP-SGIQCAHSLE----ACTCTYEDRTYSYQDVIYNTTD
GLGACLIAICGSNGTIIRKAVACPGTP----ATT-PFTFTTA--WVPHST----------
------------------------------------------------------------
-----------------------------TSP----------------------------
------------------------------------------------------------
----------ALPVSTVCVR----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSSWYNGHRPEPGLGGGDFETFENLRQRGYQVCPVLA---DIECRAAQLPDMPLEELG
QQVDCDRMRGLMCANSQQSP--P-LCHDYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCEYVP--CGPSPAPGTSPQP-----
----------------------------------------------------SLSAST-E
PAVPTPT-----------------------------------------------------
Q--------TTATEKTTLWVTP-------------------------SIRSTAA------
----------------------------------------------------LTSQTGSS
SGPVTV----TPSAPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTEWFDEDYPKSEQLGGDVESYDKIRAAG-GHLCQ
QP---KDIECQAESFPNWTLAQVGQ-K-VHCDVHFG-LVCRNWEQE--GVFKMCYN---Y
-RIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCS-DDHCRGRATTPPPTTELE--------------------------------
-----------------TATT--TTTQALFSTPQPTSSPGLTRAPPASTTAVP-------
-TLSEGLTS-P-----------RYTSTLGTATTGGPTTPAGSTEP-TVPGVATSTLPTR-
SALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTG--TAS-T----ASKEPLTTSLAPT-
-------L-TSELSTSQAETSTPRTETT----MSPLTNTTTSQGTTRCQP-KC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDFPTSGVAGGDMETFENIRA-AGGKMCWAP-K---SIECRAENYPEV-SIDQVGQVLT
-CSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSS-TATPSSTP-----
---GTT------------------------------------WILTKPTTTATTTASTGS
T-----------------------------------------------------------
--------------------------------------ATPTSTLRTAPPPKVLTTTATT
PTVTSSKAT------------------PSSSPGTATALPAL-RST------ATTPTATSV
TPI----------------PSSSLG----------TTWTRLSQ-TTTPTATMSTATPSST
PETAH-----------TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTT--TTTGFT
ATPSSSPGTALTPPVWI-----STTTTPTTRGSTVTPSSIPGTTHTATVLTTTT-TTVAT
GSMATPSSSTQTSGTPPSLTTTATTITA---------TGSTTNPSSTPGTTPIPPVLTTT
ATTPAATSNTVTPSSALGT-----------------------------------------
------------------------------------------------------------
-----------------------------THTPPVPNTMA--TT--HGRSLPPSSPHTVR
TAWTSATSG---ILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSS------RTT
ESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSS-PTSAPITTVVTMGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_37 (4199, 4292)

WS
EWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ-PL---GLECRAQAQPGVPLRELGQVV
ECSLDFGLVCRNREQVGKFKMCFNY-EIRVFCCN-YGH--CPSTPATSSTAMPSSTP---
------------------------------------------------------------
------------------------------------------------------GTTWIL
TELTTTATTTES------------------------------------------------
------------------------------------------------------------
------TGSTATPSSTPGTTWILT------------------------------EPSTTA
TVTVPTGSTATASSTQATAGTPHV------------------------------ST-TAT
TPTVTS--SKATP---FSSPGT--------------------------------------
---------------------------------ATALPAL-RSTATTPTAT---------
-------------SFTAIPS----------------------------------------
----------------------------SSLGTTWTR-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LSQT------TTPTATMSTAT-------------------------
------------------------------------------------------PSSTPE
TVHTSTVLTTTATTTGA--------TGSVATP-SSTP-----------------------
---------GTAHT----------TKVLTT--TTTGFTATPSSSPGTAR-----------
------------------------------------------------------------
------TLPVWISTTTTP------------------------------------------
------------------------------------------------TTRGSTVTPSSI
PGTTHTPTVLTTTTTTVAT-GS-----MATPSSST------------------QTSGTPP
SLTTTATTITAT--GSTTNPSST-PGTT---PIPPVLT-TTATTPAATSSTVTPSSALGT
THTPPVPNTTATTHGRS---------------------LSPSSPHTVRTAWTSATSGTLG
TTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATS--R
TTATATPSKTRTSTLLPS--------SPTS------APITTVVTMGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WS------
EWLDYSYPMPGP-SGGDFDTYSNIRA-AGGAVCEQPL---GLECR-AQAQPGVPLRELGQ
VVECS-----------LDFGLVCRNREQVGKFKMCFNYEIRVFCCNY-------------
-----GH-CPSTPATSS--TAT-----------PSSTPGTT-WILTEQTTAATT-----T
ATTGST------------------------------------------------------
--------------------------------------------------------AIPS
STPGTA-PPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATK--STATSFTPIP
SFTLGTTGTLPEQTTT---PMATMSTIHPSSTPETTHTSTVLTT--------------KA
TTTRATSSMSTPSSTPGT-TWILTELTT-AATTTAATGPTA-------------------
--------------------------------------TPSSTPGTTWILTEPSTT----
------------------------ATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV-
----ISSRATPSSSPGTATALPALRSTATTPTA---------------------------
---------------------------TSVTAIPSSSLGT-------------AWTRLSQ
T----TTP--------------------------TATMSTATPSSTPETVHTSTVLTTTT
TTTRATGSVATPSSTPGTAHTTK------------------------------VPTT---
-------------------------------------TTTGFTATPSSSPGTALTPPVWI
STT-----TTPTTRGSTVTPSSIPGTTHTAT-----------------------------
VL-TTTTTTVATG--SMATPSSSTQTSGTPPS-LTTTATTITATGSTTNPSSTPGTTPIP
PVLTTTATTP-AATSSTVTPSSALGTTHTPPVPNTTATT----HGRSLPPSSPHTVRTAW
TSATSG--------------------ILGT-THITEPST---------------------
--VTSHTPAATTSTTQHSTPALSSPH------P---------------------------
---------SSRTTES---------------PPSPGT-----------------------
-TTPGHTRGTSRT----------TATATPSKT-R--------------------------
----------------------TSTLLPS--SPTSAPITTVVTTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_50 (7192, 7290)

WSEWLDYSY
PMPGPSGGDFDTYSNIRAAGGAVCEQP-L---GLECRAQAQPGVPL---RELGQVVECSL
DFGLVCRNREQVGKFKMCF---NYEIRVF

ENSGT00760000118896_5_Linker_50_53 (7290, 7955)

CCNYGH-CPST-PATSSTATPSSTP------
----------------------------------------------G--TTWILTKLTTT
ATTTESTGSTA-----TPSSTPGTTWILTEPSTTATVT-VPTGSTATASSTQATAGTPHV
ST-TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT---RL
SQTTTPTATMSTATPSSTPETAHTSTVLTTT-----------ATTTRATGSVATPSSTPG
TAH---TTKVPTTTTTGFTVT-PSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTH
T-----PT--------VLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTT
NPSSTPGTTPIPPVLTT------TA-TTPAATSSTVTPS--SALGTTHTPPVPNTTATTH
GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT-TGTTQHST----PALS
SPHPS----------------SRTTESPPSPGTTTPGHTTAT------------------
------------------SR----------TT-----------------ATATPSKTR--
-------TSTLLPSSPTSAPITTVVTTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_53 (7955, 8050)

WSEWLDYSYPMPG---PSGGDFDTYS
NIRAAGGAVCEQPL----GLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKM
CFNYEIRVFCCN-YGHCPSTPAT-------------------------------------
--------SSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSP-
ATTPTATSSKATSSSSPRTATTLPVLTST-----------------------------AT
KSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTV-----------
----------------------LTTKATTTRATSSTSTPSSTPGTT--------------
-WILTELTTAAT-------------TTAATGPTATPSSTPGTTW----------------
--------------------------------------------------ILTELTTTAT
TTASTGSTATPSSTPGTTWILTEPSTTATVT-----------------------------
-------------------VPTGSTATASSTQATAGTPHVS---------TTATTPTVTS
SKATPSSSPGTAT-ALPALRSTAT----TPTATSFTAI------PSSSLGTTWTRLS---
------------------------------------------------------------
-------------------QTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSV-
-------ATPSSTPGTAHTTKVPTTT---------TTG----FTATPSSSPGTALTPPVW
ISTTTTPTTT------TPTTSGSTVTP------SSIPGTT------HTARVLTT-TTT--
----------------TVATGS-----MATPS--------------------SSTQTSGT
PPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP
VLTSTATKSTATSFTPIPS---------------STLW-----------------TTWTV
PAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTT
TATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATAS----------------
--------------------STLGTA-----HTPKVVTTMATMPTATASTVPSSSTVG--
----------------TTRTPA----------V-LPS-SLP-TFSVSTVSSS-VL---TT
LRP---TGFPSSHFS-TPCFCR--------------------------------------
------------------------------------------------------------
---------------------------------------------------------AFG
QFFSPGEVIYN------KTD--------RAGCHFYAVCNQHCDIDRFQ-GACPTSPPPVS
SA----------PL----------------------------------------------
------------------------------------------SSPSPAPGCDNAIPLRQV
NETWTLENCTVARCVGDN-RVVLLDPK--PVANVTCVNKHLPIKVSDPSQPCD-FHYECE
C-----------------I

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLY
LDNHYCTASATAA-AARCPRALSIHYKSMDIVLTV-TM-VHGKEEGLILFDQIPVSSGFS
KNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDC
LQRDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TTAASCKDMAKTWLVPD----SRKDGCWAPTGTPPTASPAAPV------------
--SSTP---TPTPCPPQ-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CD--LM-------LSQVFAECHNLVPPGPFFNACISDHCR
-G---RLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLT--CPPTKVY----KPCGPI
QPATCNSRNQSPQ--------L-----EGMAEGCFCPEDQILFNAHMGICV-QA-C----
-PCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRP
RAENPCCPETVCVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRP--QL

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CSYNGT
------FYGVGATFPGA-LPCHMCTCLSGD---TQDPTVQCQEDACNNTTCPQGFEYKRV
AGQCCGECVQTACLTPDG------QPVQLN----ETWVNSHVDNCTVYLCEAEGGVHLLT
PQ--PASCPDV--S-----SCRGSLRKTGCCYSCE-E--D----------SCQVRINTTI
LWHQGCET--EVNITFCEGSCPG-ASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGS
AILHTYTHVDECGCTPFCVPAPMAPPHTRGFPAQ--------EATAV-------------
-----------

----MSVGRRKLALLWALAVALA--CTRHTGHAQDGS----SESSYE------HHP---A
LSPIARGPGGV----PLRGVTVFPSLRTIP--VVRASNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_1 (106, 139)

CST-WGNFHYKTFDG
DVFRFPGLCNYVFSEHCGAAYEDFNPATPQPGVGGPH--AEQGP--YEGGRRSHPADQGL
RPGQRPPGPAALQPVWGPHSRAAA---------TPRWRPGWALSSCG-TT---MTAC---
----CWLDTKYANKLWALWGFQRDARGQRAPL--------PQHQADT--HGIREPARWTT
PRSSVRTLSLNP-RGTAP--L---------ALG

PF08742 // ENSGT00760000118896_5_Domain_4 (334, 409)

ICEELLHGQLFSGCVALVDVGSYLEAC
RQELCFCEDT---D--LLSCVCHTLAEYSRQCAHAGGLPQDWRGPDLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--QK

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPNNMQY
HECRSPCAD-----TCSNQEHSRACEDHCVAGCFCPE---G---------TVLDDVGQT-
---GCVPVSK

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACIYNGAAYAPGATYSTDCANCTCSGGRWSCQEVPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGAHFS
TFDERQYTVHGDCSYVLT-KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV-V
VIKASGEVFLNQIY--TQLPISAANVTIFRPSTFFIIAQTSL-GLQLNLQLVP-TMQLFM
RLAPKLRGQTC-----GLCGNFNSIQADDFRTLSGVVEATAA-AFF------NTFKTQAA
CPNIRNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

KYAQHWCSQLT-DADGPFSHCHAAVKPGTYYSNCLFDTCNCERSEDCLCAALSSY
VHACAAKGVQLSGWRD-GV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CTKPMTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYHYHVSTCQPTCRSLSE-GDITCSVGFI
PVDGCICPEGTFLDDTGKCVQASN

ENSGT00760000118896_5_Linker_15_17 (1525, 1587)

CPCYHRGSMIPNGESVHDSGAVCTCTQGKLSCIGGQ
AP-TP---VCAAPMVFFDCRNATPGD

PF01826 // ENSGT00760000118896_5_Domain_17 (1587, 1638)

AGAG-CQKSCHTLD---MTC--YSPQCLPGCVCP
DGLVADGEGGCIT-VEDCPCVHNEASYRAGQTIRVGCNT-------C----TCDSRMWRC
TDDPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CAVYGDGHYLTFDGQSYSFNGDCEYTLVQN--HCGGKDSAQESFRVVTENVP
CGTTGTTCSKAIKIFLG-----------------------------------GSELKLNH
GKVEVIGTD-ESQEVPYTVRQMGIYLVVDTNIGLVLLWDKKTSIFINLSPEFKGRVCGLC
GNFDDNAVNDFATRSRSVVGDV-------LEFGNSWKLSPSCPDALAPKDPCRANPFRKS
WAQKQCSILHGPTF----------------------------------------------
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-----------

----MGTRGACWALPWALTALLVARQAEQGAL--AWW----VAGR--------------G
--------AGWAWGRRGRRQ---GPL--HA--LPAALNLAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CSA-WGDFHYKTFDG
AVFRFPGLCNYVFSAHCGASYEDFNVQLRRGLAGSKP-TVTHIVLKAPGLVLEMSNGSIL
VDGQR---------EELPYSRAGLLVERSSEYVKVGVRLVLTLL-WD-GE---DSVL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 340)

AFNEF---------YAHNARLSPLQFGNLQKLDG
PTEQCPDAQPKP-ASNCTDE-----------EGVCRRTL

PF08742 // ENSGT00760000118896_5_Domain_4 (340, 408)

LGPAFAECNALVDASAYLAAC
AHDLCRC------P----TCPCATFAEYSRQCAHAGGHPQNWRGPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMEH
EECGSPCVD-----TCSNPQRSQLCEDHCVDSCFCPPG------------TVLDDVTHS-
---GCLPLEQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGRTYAPGGSFTTSCSSCSCSGGLWQCQSLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KTCADNTFTVLAELRQCGLTDNENCLRAVTLHLDGGDTV-I
RIQADGGVFMNSIY--TQLPVSAASITIFRPSSFFLVAQAGA-GLQLQVQLVP-LMQVFV
RLDPAYRGQTC-----GLCGNFNQNQADDFTALSGVVEGTGA-AFA------NTWKTQAA
CPNVRNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPAGALSPCHSVVNPEPFHSNCMFDTCNCERSEDCLCAALSSY
VRACAAKGVLLRGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCAKYMSS

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQSYAYVVDTCPPTCRALSE-VDVTCSVSFV
PVDGCTCAEGTFLDDAGACVPARECPCYLRGTAVAPGEVVHDNGAVCSCANGKLSCLGAA
LPRSA---GCVAPMVYLDCRNTSAGAPGAE-CLRSCHSLD---VDC--FSTHCVSGCVCP
PGLVSDGAGGCVA-EEDCPCVHNEASYRPGDTIRVDCNT-------C----TCRNRRWEC
SHQPCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CVAYGDGHFITFDGERYSFGGSCEYTLAQD--YCGGNA-TNGTFRIVTENVP
CGTTGVTCSKAIKLFVE-----------------------------------SYELILRE
GSFTVVERG-PGGDPPYKTRYMGNFLVIETRGGMAVSWDRKTSVFVRLRQDYKGRVCGLC
GNFDDNAVNDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSLAGNA-------LEFGNSWKFSPSCPDALAPKDPCAANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIINGPTFAACRS--QVDSTKYYEACVSDACACDSGGDCECFCTAVAAYAQACR
DAGLCVSWR-TPDVCPLFCDYYNPHGECEWHYQPCGAPCLRTCRNPSGRCLVDLPSLE--
--GCYPECPPSKP--FFSEDQMRCVA--QCGC---------YDEDGRY------YDI-GW
RVPVSENCQSCN--------CTA-AGVQCAHSLA----ACTCTYEGRTYGYHDVIYNTTD
GLGGCLSAICGDNGTIVRRAVECPGTP----SSA-PFTFTTV------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------PTLSTVCVR----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSAWYDSGRPEPGEEGGDFETLERLWRKGYQVCSAPA---DIECRAEGLPHTPLRELG
QKVVCDRTRGLTCANREQSP--P-LCLNYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCDYVP--CGPSPAPGTSPRP-----
----------------------------------------------------SLGTTT-E
PPSTQTR-----------------------------------------------------
-----------ATEGTTPQTVP-------------------------GSPSTAA------
----------------------------------------------------LTSQTRPS
PPTVTVTPSAGSPGPSATTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTQWFDEDYPKSERAGGDIESYDKIRGAG-RDICE
RP---QDIQCQAENFPNWTLEQVGQ-K-VHCNVRFG-LVCWNHEQD--GIFKMCYN---Y
-KIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCS-SEHCRGHTSALPPATTPG--------------------------------
-----------------TATT---VSRAWSSKPQPRSSPGVTWTPPASTTAVT-------
-VLSKGPTS-P-----------IYTAPPGST------------RP-TSPGGATSILPSR-
PTQAGSTGATGRRGPSQSPTPAPTTQ-TSTAHLTG--TAS-T------KEPVTTGLGLT-
-------TRPSQPPTSYTETSTLRPETP----PSTSAGTATSQGTTGCQP-RC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDYPISGVAGGDIETLENIRA-AGGKLCEAP-V---KIECRAENYPEV-SIDQIGQVLI
-CSLETGLICRNKDQVGRFNMCFNYNLRVLCCDDYRHCPSTAVPTG-PSTPATTSMATTI
PA-------------------------------------TSSMGTTIPATTST-----GT
-----------------TSTATT-------------------------------------
-----STGTTAKGTTSLSA-----------T--IS-LG----------------------
---------------------------------------------------TTSPSTTSL
A-----------------------------------------------TRSSSVTRPSTT
AT------------------------------------TSPP--ITQRVIST--TQRN--
-----------------------------------LNFSVPGPSTLPASTTSP-------
------------------FHTTG---------------------------KPTSGTL---
-----------------TT-----------------------------------------
------------------------------------------------------------
-----------------------------STRPPLT------------------------
-----------------------------------STPHTAPLLT---------------
------------------------SSSGRTT-------GTTLPSSRPTPSKGCAPRCA

PF13330 // ENSGT00760000118896_5_Domain_37 (4199, 4292)

WT
DWFDEDYPIPGPDGGDFETYAVIRAAGHTFCEH-PQ---DIQCRSEKKPDKPLEAVGQVV
YCDVRFGLVCRNRDQLGPVKYCDNF-HMRLLCCDDYSH--CASTPTATGSTATPSSA---
------------------------------------------------------------
------------------------------------------------------TTSLAT
SSSTSTSSGITSTATTSS------ATSTATSSPATTS-----------------------
---------------------------------------SATSSSAS---------TSSG
ITST--------------------------------------------------------
---------ATTSSA---------------------TSTATSSPATTSSATSSSA-----
----------------STSSGI--------------------------------------
-----------------------------------------TSTATTSSAT---------
-------------ST---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------ATTSPATSSSASTSSGITSTATTSSAT-----
--------------------------STATSSPAT-------------------------
------------------------------------------------------SSSTS-
---TSSGITSTMTTSSA--------TSSPATTSPATS-----------------------
---------SSAST----------SSGITSMATTSSATSTATTSPATTS-----------
------------------------------------------------------------
------TG----------------------------------------------------
-----------------------TTSTGSISPATT------------------------S
MGTTST------GSISIAT-IS-----MGTTSTAT------------------TSLGTTS
PSTTSL--ATTS--SLVTGPSTTATTFP---WITKTVN-VSTTKRGFTFSVPSPSA----
----PLVSTTSPFHTTG---------------------QLTS------------------
----------------GTL-TTSTRPPLTSTPHTAP--------------LLTS------
------SSGHTVGTTLP--------------------SSRPTPSKGCVPQCA

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WT------
EWYDVDSPIPGP-DGGDFETYAVIRA-AGHTFCEHPQ---DIECR-SEKEPDKPLEAVGQ
VVYCD-----------VRFGLVCRNRDQVGQFKLCLNYLIRVFCCNY-------------
-----SH-CLSTPSTTT--ASS-----------LGT--SPT-WATTLSPSTTAL------
------------------------------------------------------------
--------------------------------------------------------SLPT
PNPRD---------------RSTTSTAVPT------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------SC-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------QPAC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

HWTDWLDSDQ
PQPGRFGGDIETYYHIMDAGGQLCLEP-T---AIECEAVLFPGVSL---GLLGQVVRCDV
RYGLICRNHRQKS-GQTCL---NYHIRVRCCDYSH-CAST-TSA----LPSSTP------
----------------------------------------------VPTPHSTLSTPTTT
SIGTTSSTSNSPATSSSASTSSGITSTVITSSATSTA-----------------TASPAT
TSLATTSPGTTSSG---------------------------TTSLASNSVGTTSIGSTSI
ATTSTSTTKMRTTSPATTSNA--TSIVTTST-----------ATTSLATSSS--SSTSSG
IT----STAIMSSATSTATTS-PAT---TSTGTTSTGSTSVATTSTGTTSTETTSPGTIS
TG----TT--------S-------LATTSIGT-------TSA-------AITSTATTSPA
TSSSAS---------------TSSGIISTAMSSTTATAT--TFPATTYTATTFSVT----
-------------T--------------STETTSSAT-------------TS----PATT
SPATT----SKGTISTSSTSTATTSTGKTSLATTSPATSSSAT---ITSPATTST--GTT
STETTSRGTTSAGT-----------------------TSLAI---TSIGTTFTATSSPAT
T------------------------------------STATT------------------
----SPATS---------------------------------------------------
------------------SSA-----------------------------------STSS
AITSTVTTSSA---------------------------------------------TST-
ATT---------------------------------------------------------
---STATTSMGTTSTGTTSIG---------------------------------------
-----------------------------TTSIGSTSIATTSPATT--------------
-SM--------GTT----SPSITSM---GTTS----------------------------
-------------------------------------------------------TATTF
SRNLNFSVPSPSNL----------------------------------------------
------------------------------------------------------------
----PASTTSLFH-TTGKPTSGTL-------------T------TS---------TRPPL
TSTPHTAPLLT---------------SSSGRTTGTTLP--------------SS------
-----RPTPSKGCAPRCA

PF13330 // ENSGT00760000118896_5_Domain_54 (8719, 8941)

WTD-----WFDEDYPI---------------------PGPD-
-------GGDFETYAVIRAAGHTFCEHP----QDIQCR----SEKKPDKPLEAVGQ----
-------VVY------CDVRFGLVCRN------RDQLGPV------KYCDN---------
------------------------------------------------------FHMRLL
CCDDYSHCASTPTA----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------TGSTATPSSAPWT-
-----------------THTAV----------V-SPS-SLP-ASSTSTRSTS-VI---TT
LRP---TSSPSSSFSQTPCFCQA-F----GQLFSP------------GE--SIPRQLGLP
WSLWLSPTAAISLRPV---------------PGPTC------------------------
----DTC---------------------SLRPQLCLCCP-----Q-GSTGWSLDVATSRM
VLSLPGDVIYN------KTD--------RAGCEFYAVCTEHCDIERFQ-GHCPTSPPPAP
ST----------PL----------------------------------------------
------------------------------------------PPTSPPPGCDNAIPPRQV
NESWTLENCMVARCEGDN-HIVLLPPK--PVANVTCVNGQQPLKVWNQSQPCD-FHYECE
C-----------------S

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGDSHYLTFDGTSYSFLDNCTYVLVREIHPRHGNLTVL
LYSHYCGPSAPAS-ATGCPRALSIHYESMDIVLTT-TT-VRGKEESLILFGRVRVTRGFT
KRGVSVSLTGAGTMGVDIPAIGASITFDGHSFQVRLSYSLFGNNTEGQCGTCTNNQKDDC
RRPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9999)

TIAPTCKDMAKSWLVPD----DSPDGCWAPTGAPPTASPMSPT------------
--PHRP---TPTQCPPE-------PL-------LFPVG

PF08742 // ENSGT00760000118896_5_Domain_57 (9999, 10054)

RQCHGLVPPGPFVNACISDGCR
SS---HPGVPCQSLEAYAALCRAHGVCSDWRNATGGLCDLP--CPPAQVY----KPCGPV
QPESCDSRSQSPV--------S-----GGLAEGCFCPDGQILFNTLKDICV-HT-C----
-ACVGPDGLPKLPGERWVSQCQDCVCDEGSVSVQCEPKRCEPQAQPPTCDGAGVVAVTRP
RADEPCCPETVCVCNTTTCPPPSPPTCGPGQVPTRTQEEGQCCPTFVCTP--KLCTYNGT
------HYGVGTTFPGV-VPCHTCTCLSAD---PQDPTVQCEEDACN-TTCPQGFEYVSV
AGQCCGECEQHACLTPDG------QLVQPN----GTWVNSQVDNCTEYRCEVENGQHVLI
PQ--PSPCPDV--I-----SCRGTLRKTGCCYSCE-EV-D----------SCQVHVNTTV
LRHGDCETEGVVNITFCEGSCPG-ASKYSAEAQAMEHQCTCCQESRVHAETVSMRCPDGT
AIVHTYTHVDECGCEPSCVPLPTAPTDAPVLPV---------------------------
-----------

----MGVGRRKLVPFWVLALALT--FCQHTGQAHQDT----LKSDHV------RHS---D
FSFLQG-HDAA----PLHGVTIIPPLKTIP--VVRALGPAHTGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 268)

CST-WGDFHYKTFDG
QVFRFPGLCNYVFSAHCGAAYEDFNIQLRRSRESNST-TLSRVTMKLDGLVVELTKSSVL
VNN---------HPVQLPFSQSGVLIELSSSYLKVVARLGLVFM-WN-DD---DSLL---
----LELDTKYTNKTCGLCGDFNGSPE

ENSGT00760000118896_5_Linker_0_4 (268, 335)

SSEF---------LSHNVRLTPLEFGNLQKLDG
PTEQCHDPLPVP-QKNCS-IR---------Y-GI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEEILKSQLFSDCSALVDISSYLEAC
RQDLCLCESP---D--LSSCICHTLAEYSRQCAHAGGQPQDWRGPNL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CS--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCVD-----TCSNPQRSQACEDHCVAGCFCPK---G---------MVFDDISQT-
---GCVPVSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACLYNGTSYAPGTNYSTDCTN-TCSGGRWSCQEVPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVLGGSHFS
TFDERQYTVHGDCSYVLS-KPCDSNIFTVLAELRKCGLTDSETCLKSVTLSLGGGQTV-V
TVKATGEVFVNQIY--TQLPVSTANVTLFRPSTFFIIAQTNL-GLQLEIQLVP-IMQVFV
RLAPVLRGLTC-----GLCGNFNSIQADDFQTISGVVEGTAA-AFF------NTFKTQAA
CPNVRNIFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSQLT-DASGPFSQCHTTVNPSTYFSNCMFDTCNCEKSEDCMCAALSSY
VHACAAKGVLLSDWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKATTT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYQYHISTCQPTCRALNE-EDVTCHVNFV
PVDGCTCPAGTFLDDSGKCVQATS

ENSGT00760000118896_5_Linker_15_17 (1525, 1582)

CPCYHRGSIVPNGESVHDSGAICTCTQGTLTCIGGP
AP-TP---VCDAPMIYFDCHN

PF01826 // ENSGT00760000118896_5_Domain_17 (1582, 1638)

ATLGDTGAG-CQKSCHTLD---MTC--YISECVPGCVCP
DGLVADGNGGCVV-AEDCPCVHNEATYRPGETIRVGCNN-------C----TCENRMWRC
TDKPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CAVYGDGHYLTFDGQRYSFSGNCEYTLLQD--HCGGNGSSQDAFRVVTENIP
CGTTGTTCSKDIKIFLR-----------------------------------NYELKLSD
GKVEVVQKD-VGQEPPYYVHQMGIYLVVETDVGLVLLWDRKTSIFLRLSPEFKGKVCGLC
GNFDDNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVGDV-------LEFGNSWKFSPSCPDALVPKDPCTANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIINSETFTACHA--HVEPAKYYEACVSDACACDSGGDCECFCTAVAAYAQACH
EVGVCVSWR-TPDICPLFCDYYNPEGQCEWHYQPCGAPCMRTCQNPSGHCLHDLHGLE--
--GCYPKCPPTAP--IFDERKMQCVS--NCIPL--PPPLPPCRINGKL------YRL-GA
KVPSDKNCHSCI--------CTE-NGVSCSYDAS----ACVCTYNGQHFHSGEIIYHTTD
GTGGCISAYCRANGTIERNVDTCSPTTPM--P---PTTFSFS--TP------VVM----T
SMPPSSTQT---------------SS---------------PSIVY----TGPPSTAT--
------STTSSMLSVKTPAT-ASTLT--TSTM----------------------------
------------------------------------------------------------
----------TSTLTMPGCQ----------------------------------------
----------------------------------------------------------EE
CV

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSPWMDVSRPGRGIDSGDFDTLENLRAHGYQICRVPR---AVECRAEDAPEVPLHALG
QRVECSTTVGLTCHNKDQVS--E-LCENYQIRIE

ENSGT00760000118896_5_Linker_28_29 (2615, 2906)

CCTPIS--CPTSSGPSQSTQLITSRT
TTK--------------GPT--T-SVAPVTSTD------------------H-TD-ST-V
IP--GPSTHALSPF----------------------------------------------
-----------PSPSHPFSSA--------------------------PSPSTSAPIGS--
T--------TVK--TT--LSTTSPIP--EP----TSAT----------------WSIPTS
GST------IASFETTHECKRELCS

PF13330 // ENSGT00760000118896_5_Domain_29 (2906, 3007)

WTDWIDGSYPGPDRNSGDFDTFENLRSKG-YKFCE
KP---QNVRCRAQFFPNTPLEELGQ-N-VTCNPEEG-LLCLNKNQL----PPICYN---Y
-EIQIECCTVVDVCSMTSATTHS-TSHE--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-------------------VS---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------TETKTPW-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------TTSSHSSPT---------------------------
------------------------------------------------------------
---------------------KE--------T---------------------STLS---
------------------------------------------------------------
--------------------------------------------ATIHPKTW--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------AT-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------GSSHTITTPVSSHCQLQC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

NWTKWFDTDF
PVPGPHGGDLETYSNILRMGEKICHRDHTEITQLECRAENHPEVRV---EDLGQVVQCDP
TIGLVCRNRDQQDMSGMCL---NYEVRVLCCRLPEGCPVTYGTPPVTSSHKPSF------
------------------------------------------------------------
------------------PV----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------V--
STPSVPSTS-LSSPR-------------VH------SA--------LP------------
------------------------------------------------------------
------------------------------------------------------------
-------CLCNVSG----R------------LYSIGSI----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------IY-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------N------QTD--------LDGHCYYALCSQDCQVVRGVSQDCPSTMPPPT
PAA--STSA---ST----------------------------------------------
------------------------------------------ITPVTAWDRCNVLSAILK
GETWPMPNCSQATCEGNN-VISLSPRQCPEVKAPSCANGYPPLKVDDQD-SCC-QHYQCQ
C-----------------V

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9905)

CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVFGHFRVL
IDNYFCDLG---D-SVSCPQSIIVEYHQDRVVLTRR-P-VGGIMTNQIIFNDKVVSPGFQ
QNGIVVSRVGIK-MYVTIQEIGVQVMFSGLIFSVEVPFNLFANNTEGQCGTCTNDKKDDC
RLPG

ENSGT00760000118896_5_Linker_56_57 (9905, 9981)

GAM-TSCSDMAPHWKV------PNQPSCQGPPPTSISVVP----------------
----SP---SPTPCPPS-PI

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10055)

CQ--LI-------LSKVFQSCHDIVPPLPFYKGCLFDYCH
GL---GLEVVCSGLELYASLCAAKGRCIPWRSQTNNSC--REC-PAR-----------PP
--------------------------------SLHQAFPPELTHR-SSSCI---------
--------ISLQPGHTISFNCQDCICKEGTL--TCQRKSCP---Q-TTCLEPGFVPVPEA
LEAGQCCPRFSCVCNSSHCP-PPLH-CPNNSSLMVTYKEGACCPSQNCIG-RKG

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CEFNGT
------LYQPGDVVSSS--LCETCLCQAPSNPHSDVFVISCETELCN-TLCPTGFEYQDE
PGQCCGRCVQKGCTFK-NTSCA---SFQPG----ESWPEP-GDPCVTHKCEKLQDVFIVV
TT--KRECPKINCP-----QGQVQLREDGCCHDCL-I--TQ--------QKCTVHQRQQI
IHQQNCSSEGPVSLSYCQGNCGDSTSMYSLEANTVEHKCECCQELQTSQRNVTLHCDDGS
SRTYSYTQVEKCGCLGQRCHALGNTSYSESSESEFKSKESKEHGQKLAFGASKEVPGPFQ
-----------

------------------------------------------------------------
---------------------------------------------

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 285)

CSS-WGNSHFRTFDG
DIFQFSGSCNYVFAKHCGSTYEDFTIQIRRSVVEKIP-VLTQISMKLDGVSLVLGNGQIT
VNEEK---------VEIPYSFSGIKLVTHLIDYTV--SNDAIFA-LD-SL---LSLY---
----LELDKKYANKTCGLCGDFNGIPVYNEF---------IINN

ENSGT00760000118896_5_Linker_0_4 (285, 328)

VQLTDVQYGNMQKLDG
PTETCADLQATP-KVNCTDSS------

PF08742 // ENSGT00760000118896_5_Domain_4 (328, 409)

ISKQRSLCQIVLTSSAFSSCNFLVNPSQYIELC
VQDLCECSGD---I--LGFCLCNTFAEYSRQCSHAGGQPSNWRTEQLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--MK

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CSFNMEY
SECGSPCPN-----TCTNPYRSSVCDSNCIDGCSCPK---G---------TVFDDIGNT-
---GCIPKSS

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCIHDGKTYASGTGYSAECKNCNCNEGIWACEDVACVGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CSVTGGSHIT
TFDSRHYSFYGDCSYVLA-KSCNNNEFNVIGEIRKCGLTNTETCLKGVIISLGHGEDQFI
YVKEGGSLYVNSLF--TQVPFSSASVTIFRPSSFFIIVQTSI-GLQLQIQIVP-NMQVFI
SLTPSDESNIC-----GLCGNFNGNQEDDFRVHSGVIEGTAS-SFA------NSWMTQAG
CPTVTNTFEKP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CDLS
VE-N

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1456)

FNFANHWCSMLT-DTSEAFVQCHQKVDPNIYKENCMFDSCNCADSEKCMCAAISSY
VYACARAGIILTGWRE--------------------------------------------
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-----------------------------------ALNPSHNLQI

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 286)

CST-FGNYHFKTFDG
DIFHYPGGCNYVFASHCKSSFEEFNIQIRRSLRETIP-VISSINIKIEGANIHLTDQNVT
FNNEE---------VNLPYRFGGIQISKSDAYIRVFSIIGVEML-WN-EE---DSLL---
----LELSPKFANQTCGLCGDFNGIPIHNEF---------IVNDV

ENSGT00760000118896_5_Linker_0_4 (286, 318)

QLTETQYGNLQKYNG
PTERCDDVAEQQ-EETC

PF08742 // ENSGT00760000118896_5_Domain_4 (318, 409)

MSQN----------GDLCSLVLNGPAFQECNQLVDASKYIELC
EQDFCGCSEN---S--TAFCICNIFTEYSRQCAHAGGKPQNWRTSELC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--LR

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CDYNLEY
NECGTACPD-----TCSNFERSLVCDEHCKDGCFCPI---G---------MVYDDVNFS-
---GCIPKEQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCTYNGKVYATGTGYTEKCQTCTCHGGKWNCDKSPCYGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CALEGGSHIT
TFDRNRYNFHGNCFYTLS-RTCENDLFRIVAELRPCGQTDTETCLRSVTISLNEGKD-LI
VVGSEGIVHVNSLD--SQLPVSTANAVIFKPSSFFIIVQTKV-GIQVTIQHKPSDMQVYI
RADPALMNTTC-----GLCGNFNN-KTDDFNSPNGVHQGTGA-PYG------NTWKAQAD
CPKVKNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CALS
SE-S

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1461)

ERYASHWCSMLK-DTEGPFSACHKSVDPTYYYKTCLFDTCNRENTENCMCTALSSY
VYACSREGIYLKDWRT-SVCSNFT-NCPTSFTYNYTISTFQPTCRSISE-PDYTYDVSFV
PVDGCICKDGTYLDNTGNCVPPSLCPCFNNGATVPPGQVIHEKGAVCTCTNGKLDCIGKK
PI-QK---ECEYPLVYFNCSNTSAETKGSE-CQKSCSTFD---KEC--YSTKCISGCMCP
SGLMLDDKGNCIQ-ESDCPCVYNDEFYSPGEKIKVQCNT-------C----ICRNRMWDC
TDNTCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1877)

CTAYGDGHYVTFDNKRYQFSGNCQYTLAQD--FCS-NDTTAGTFRVITENIP
CGTTGTTCSKSIKVFLG-----------------------------------NYELILGD
ENVEVINREVG-EYVPFNVLQMGIYLVIEAANGLVLVWDKKTTIYIKLAPDFQGTTCGLC
GNYDVNAENDFLTRSM

ENSGT00760000118896_5_Linker_20_26 (1877, 1919)

SEVGDV-------NEFGNSWKLSPSCQDAMAVKEPCSTNPYR

PF08742 // ENSGT00760000118896_5_Domain_26 (1919, 1996)

KA
WSQKQCSIITGPTFSSCHA--LVNPVNYYEACVNDACACDTGGDCECTCTAVAAYAQACS
EAGECVQWR-TPKMCPIFCDFYNHDEECEWHYKPCGAPCMKTCRNPTGVCYNNLSGLE--
--VSGEGCPISRHTSIFCNKRTACTA--ICKIW------FSCKLSGKL------YK----
-VPGD--------THLDWSYCTQ-NGKECSNESVTCQIIVCCYYEGKNFLPGEVIYSTMD
GIGGCIEAICSDNSTIKRNIGPCTSTL---GPST-IFNFSTS--SSIPTSRSTQPSV--S
VSPGSVTS----------------------------------------------------
-------HTGLITTATSPGTVSSTVGIDISNT----------------------------
------------------------------------------------------------
----------SQPTIPSKSQ----------------------------------------
--------------------------------------------------DHTTTISTYN
CTWSDWYDVSRPGLGPNDGDFETFDNIKAKGFDVCKNPT---KVECRAKEYPYQAIKELN
QNVSCSKKDGLICVNTKN----A-ICHNFEIRVECCEYRKCHEYSRTTASQYSTSESSA-
-IS----S------------ATASSPRSPTTSITTTLSSIVTEGPSP-----STSLTT-T
PLPMTQSHSSSLIS----------------------------------------------
-----------TT---------------------EKISVPGTKVTPSPPPSILTSTLK--
----------------------SPV--------I----TSASGTSPRSQTT---------
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-----------

----MGALSTCRTLVLALAAVLLVQQAAKQRQPR--------------------------
----VNQQPTMGFSAPKTRA---PQPREGY--PVGALNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSEHCGAAYEDFNVQLRRGLVGSRP-VVTRVVIKAQGLVLEASNGSVL
VNGQR---------EELPYSRTGLLVEQSGDYVKVSIRLVLTFL-WN-GE---DSAL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 335)

AFNEF---------YAHNARLTPLQFGNLQKLDG
PTEQCPDPLPLP-ASNCTDE-----------EGI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CHHTLLGPAFAECHALVDTAPYLAAC
AQDLCRC------P----TCPCATFVEYSRQCAHAGGQPQNWRRPEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPVNMQH
RECGSPCVD-----TCSNPQHAQLCEDHCVDGCFCPPG------------TVLDDVTHS-
---GCLPLGQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGRTYSPGASVNTTCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIT
TYDEKLYDLHGDCSYVLS-KKCADGSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA-I
RVQADGSVFLNSIY--TQLPLSAANITLFTPSSFFIVVHTGL-GLQLLVQLVP-LMQVFV
RLDPAHQGQMC-----GLCGNFNQNQADDFAALSGVVEATGA-AFA------NTWKAQAT
CTSARNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPTGSFSRCHSVINPKPFHSNCLFDTCNCERSEDCLCAALSSY
VHACAAKGVQLSGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKYMQN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQSYAYVVDACQPTCRGLSE-ADVTCSVSFV
PVDGCTCPTGTFLNDAGACVPARECPCYVHGTVLAPGEVVHDEGAVCSCEGGKLSCLGAS
LQKST---GCVAPMVYLNCSNSLAGTPGAE-CLRSCHTLD---VGC--FSTHCVSGCVCP
PGLVSDGSGGCIA-EEDCPCVHNEATYKPGDTIRVDCNT-------C----TCRNRRWEC
SHRLCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CVAYGDGHFITFDGERYSFEGSCEYILAQD--YCGDDA-THGTFRIVTENIP
CGTTGTTCSKAIKLFVE-----------------------------------SYELILQE
GAFKAVARG-PGGDPPYKIRYMGIFLVIETR-GMAVSWDRKTSVFIRLHQDYKGRVCGLC
GNFDDHAINDFATR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SRSVVGDA-------LEFGNSWKLSPSCPDALAPKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACRS--QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH
DAGLCVSWR-TPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLE--
--GCYPTCPPSQP--FFNEDQMKCVA--QCGC---------YDRDGNY------YDV-GA
RVPTAENCQSCN--------CTP-SGIQCAHSLE----ACTCTYEDRTYGYQDVIYNTTD
GLGACLIAICGSNGTIVRKAVACPGTP----ATT-PFTFTTS--WVPHST----------
------------------------------------------------------------
-----------------------------TSP----------------------------
------------------------------------------------------------
----------ALPVSTVCVR----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSSWYNGHHPEPGLGGGDFETFENLRQRGYQVCPVPA---DIECRAGQLPDMPLGELG
QQVDCDRVRGLMCANSQQSP--P-LCHDYELRVL

ENSGT00760000118896_5_Linker_28_29 (2615, 2905)

CCEYVP--CGPSLAPGTSPQP-----
----------------------------------------------------SLSAST-E
PAVPTPT-----------------------------------------------------
Q-----TT---ATEKTTLWVIP-------------------------SIRSTAA------
----------------------------------------------------LTSQTGSS
SGPTTV----TSLAPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTEWFDEDYPKSEQLGGDVESYDKIRAAG-GHLCE
QP---KDIECQAESFPNWPLAQVGQ-K-VHCDVRFG-LVCRNWEQE--GIFKMCYN---Y
-RIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCS-ADHCRGRATTPPPATSLE--------------------------------
--------------------------TVLFSTLQSTSSLGVT-----STTAVP-------
-TLSKGLTS-P-----------RYTGTLGTATTGGPTVPAGSTEP-TVPGVATSNLPTH-
SVLPGTTGSSGTWHPSQPPTPAPTTMATSRAHLTG--TAS-S----SSKQPLTTSLAPT-
-------L-SSELFTSQAETSTPRTETT----LSRLTETTTSQSTTRCQP-KC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDFPTSGVAGGDMETFENIRA-AGGKMCWAP-K---SIECRAENYPEV-SIDQIGQVLT
-CSLETGLICKNEDQTGRFNMCFNYNVRVLCCDDYSHCPHTAAPTT-GSTA---------
TTPTS-----------------------------------TGSTATTP------------
--------------TMLSTTTIT---------------------TMATTSK---------
--------------------------------------ATPSHTPATAATPNVLTTMTTT
PTVTGSKAI------------------PSSSPGTAPTLPAL-TS-T-----ATTPTATSF
TAI----------------PSSSLG----------TTWTLTAQ-TTTPTATMSTARPSST
P----ETAH--I-----STVLTTTATTTGATGSMATPSSSPGTAYTTKVLTT--TTRGFT
ATPSSSPGTAPTLP----G-RIGTNTTPTTSGSMVTPSSIPGTTHTPTVLTNTT-TTVAT
GSMVTPSSSPQTTGTPPALATTGTTITA---------TGSTTTPSSAPGTTPISPVLTTT
ATTPAATSTTVAPSSALGT-----------------------------------------
------------------------------------------------------------
-----------------------------THTPPVLSTMA--TT--HGRSQLPESPRTVP
TARTSM--A---TSGATHITEPSTVTSHTPVGTTGTTPHSTPALSSPHTHS------RTT
ESPLSPGKTTPGLTTATSRTTATATTSETRASTLLSSS-PTSAPTTPVVSTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_37 (4199, 4292)

WS
DWLDYSYPMSGPSGGDLETYSNIRAAGGAVCEQ-PL---GLECRAQAQPGVPLRELGQVV
ECSLDFGLVCKNRQQVGKFKMCFNY-EIRVFCCN-YGR--CPSTLATSSKATPSSTL---
------------------------------------------------------------
------------------------------------------------------ETTGIL
TEPTTTAI--TT------VATGSTAMP----------SSTPGTTAILT--------EPTT
TAITTVV-----TGSTAIPSSTSGTTQITKVFPTTTATTEATGSTANPSSTPGTTGST--
----------ATSSSTPGTTWIFT------------------------------EPTTTL
TTNVATSSTVTPSSTPAT------------------------------AATSELLTTMAT
KPTATG--SKATP---STSPGT--------------------------------------
---------------------------------APTLPVVLTSTATTPTAT---------
-------------SFTAIPS----------------------------------------
----------------------------SSLRTT--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------WNLTA---QT------TAPTATLSTAH-------------------------
------------------------------------------------------ASSTPR
TTHTSTALTTTATTIQA--------TGSTATL-L-TS-----------------------
---------GTAHT----------SKVLTTMAITTSSTATP-------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------SSMTPSSI
PGTTHTPTVLTNTTITVAT-GS-----MATPSSSP------------------QTTGTPP
ALATTGTTSWLR--RP--TPSSTPPGQT---WISTST-----------------------
----------------N---------------------QLQPSQ----------------
---------QWDHRAA--SSHEAKPSTAITTVVTHSRTTESPLSPGKTTPGLTTATS--R
TTATATTSKTHTSTLLPS--------SPTS------APTTPVVSTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WS------
DWLDYSYPMSGP-SGGDLETYSNIRA-AGGAVCEQPL---GLECR-AQAQPGVPLRELGQ
VVECS-----------LDFGLVCRNRQQVGKFKMCFNYEIRVFCCNY-------------
-----GH-CPSTPATSS--KAT-----------PSSTLGST-WILTEP-TTTAI-TT---
VATGST------------------------------------------------------
--------------------------------------------------------TIPS
STPGTT-AILTEPTTTAITTVVTGSTAIPSSTTGTTRITEVFPTTTAMTAA---------
------------------------------------------------------------
----TGSTA-NPSSTPGT-TWIFTEPTT-TATITVATGSKA-------------------
--------------------------------------TPSSTPASTWILTEPTTT----
------------------------AVTTVATGSTAMPSSTQGTTGSLTEPTNT-ATITVT
----TSSTAMPSSTPGMTSILTEPTTTAITTVATRSTATPSSTPETARIVTEPTTT----
---------------------ATITVATSSTATPSSTPGT-------------TLILTEP
TTTAITTV--------------------------AP-GSTATPTSTLGTTGILTEPTTTT
ITTVATRSTATHSSTPGTTGILTELTTTAITTVAPGSTATPSS-TPGTTGILTEPTTTAT
ITVATGSTAIPSSTPGMTSILTAP-TT-----TAITTVTTGSTATPSSTPGKTSILTELT
--TTAI---TTVATGSTATPS-TPGTTRILT-----------------------------
EPTTTAITTVAPG--STAMPSSTPGTTGILTE-PTTTTITTVATRSMAMPSSTPGTTGIL
TEPTTTTITT-VATRSTATHSSTPGTTGILTEPTTTAITTVATGS---------------
-----TPTTTAIT-TVAPGSTAAPSSTPGTTGILTEPTTTAT-------ITVATG----S
TAIPSSTPGMTSILTEPTTTAITTVATGSKAKPTSTPGTTGILTEPTTTATI--------
--TVATGMTSILTEPTTTAITTVAPGSTATPSSTPGTTGILTEPTTTATITVATGSTAIP
SSTPGMTSILTEPTTTAITTVTTGSTATPSSTPG--------------------------
----------------------TTGILTELTTTAITT-VATGSTATPSTPGMTSILTEPT
TTAITTVAT--------GSTATPTSTP-G---TTGILTE-PTTTTI---TTVATRSTATP
-----SSTPGTTGILT--------EPTTTAITTVA-TGST-AIP------SSTP------
----------------------------------------------G--MTSILTEPTTT
AITTVAPGSTA-----TPSSTPGTT-GILT------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------EPTTTATITVATGSTAIPSSTPGMTS
IL----TE--------PTTTAITTVATGSMATPTSTPGTTGILTEPTTTAITTVATGSM-
ATPSTPGTTGILTEP------TTTAITTVT-TGSTATPT--STPGTTGILTEPTTTTIT-
---TVVTRSTAVPSSTPGM------TSILTEPTTTAI-TTVATGSTATPTSTPGTTGILT
GPTTT---------ATI-----TVATGSTAIPSSTPGM-TSI----LTEPTTTAI-----
------------------------------TTVATEPTTTAITT-VTTGSTATPTSTPGT
TGILTEPTTTTITTVA-------TRSTAVPSSTPGMTSILTEPTTTAITTVATGSTATPS
---STQG-TTGILT--------------EPTTTTV-----TTVATKSTAVPSSTPGKTSV
LTELTTTAITTTGSTATPSTPGTTGILTE---------------------------PTTT
TITTV-ATGSTAMPSSTPGTTGFLTEPTTTATITVATGSTAIPSSTPGMTSILTGPTTT-
AIT---------------------------------------------------------
-TVATGSTATPTSTPGMTGILTEPTTTATITVATATPSSTPGMTGILTEPTT--------
---------------A----------ATITVATGSTAIPSSTPGMT--------------
-SILTEPTTT-------------AITTVATGS-TATPSTPGTTG----------------
--------------------------------------------------ILTEPTTTAI
TTVATGSTATPTSTPGMTGILTELT-----------------------------------
-------------TTAITTVAPG-------------------------------------
STATPSSTPGTTG-ILTEPTTAATITV----ATGSTAI------PSSTPGMTSILTEPTT
TAITT---------------------VATGSTA---MP--------------SS------
-----TQ-GTTGILTEPTTTT-------STAVPSSTPGKTSVLTQLTTTAITTT--GST-
-------ATP-STPGTTGFLTEPTTTAT----ITVATG----SMAIPSSTPGTTSI----
-LTAPTTTAI------TTVTTGSTATP------SSTSGKT------SILTELTTTAIT--
----------------TVATGS-----TAMPS--------------------TPGTTRIL
T-EPTTTAITTVATGSTASPSFTPGTTGILTEPTTTTITTVAMRSTATPSSTLGTTGILT
EPTTTAITTVATGSTAIPS---------------STLGTTRIHTEPTTTA----------
----TISVATSSTATPSSTPASTWFLTE--------------------------------
------------------------------------------------------------
--------------TMATRSIAIPSSTVGTAGTPKVLTTTATRPTATGSTVPSSSTLGT-
-----------------THTPA----------V-LPS-SLP-AFSMSTVSSS-VL---TT
LR----------------------------------------------------------
-----P-----------------------------THFPSSHFSTP--------------
----------------------------------CFCRA-----F-G-------------
QFFSPGEVIYN------RTD--------RAGCQFYAVCNQHCDLDRFQ-GTCPTSPPPAS
ST----------LL----------------------------------------------
------------------------------------------PSPSPAPGCDNAIPPRQV
NETWTLENCTVARCVGDN-HVALLDPK--PVANVTCVNKHLPIKVSDPSQPCD-FHYECE
C-----------------I

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSVWGSSHYSTFDGTSYTFEGNCTYVLMREIHARLGNLSLY
LDNHYCAASA--A-AASCSRALRLHYKSMDIVLTV-TT-VHGKEEDLILFDQIPVSSGFS
KNGVLVSVTGTTTMRVDIPAQGVSVTFDGHIFQARLPYSLFHNNTEGQCGTCTNNQRDDC
LQRDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TTATSCKDMAKTWLVPD----SRKDGCWAPTGTPPTASPPAPV------------
--SSAP---TPSPCPPQ-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10053)

CD--LM-------LSQVFAQCHDLVPPGPFFNACISDGCQ
-G---HPEVPCQSLEAYAALCRARGVCSDWRGATGGLLDLW--VPGPL------------
---LSPCRNQNPQ--------L-----EGLAEGCFCPGDQILFSAHTGTCV-QD-C----
-PLRDPL-NPFQPGQQWISNCQSCVCDEGSMSVQCKPLPCEAQGPSSPCSHPGFVTVTRP
RANNPCCPETVCGKTLWSRG-ARHR------------VTGDR------------AVPPSH
------PLQVGAIFPGA-LPCHTCTCLSGD---TQDPTVQCWEDACHNTTCPQGFEYKRA
VGQCCGECVQTACLTPDG------PPVQVT----SEACGGRSQ---------------LP
PW--RPSPPTG--L-----RSGGAL----HLPFLL-P--D----------SCQVRVNTTV
LWHQGCKT--EVNITFCEGSCPG-ESRYSAEAQAMQHQCTCCQERRVHEETVPLRCPDGS
TVLHTYNHVDECGCTPFCVPAPMAPIYPPGFLAQ--------EATAV-------------
-----------

------------------------------------------------------------
----------------------------------------MSNEI

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 285)

CSY-W-NFHYNTFDG
DIFYFPGTCNYILSSDCKSTYEDFIIQIQNTLENGTI--YTKIIMKIDMLIVVLLNNTVL
VNG---------ELTELPHSSSGVMINKIGVYTKVTSKIGLEFN-MN-DD---GSLM---
----LRLDPKYSNETCGLCGDYNGMSKINEFT--------SSSG

ENSGT00760000118896_5_Linker_0_4 (285, 317)

IEISETEFGNLQKVNV
PNEKCEDVVDPN-WES

PF08742 // ENSGT00760000118896_5_Domain_4 (317, 409)

CN--E---------TGEICANILNGPSFVDCLLVLPIDDYVYSC
MEDLCTCKED---M--SSDCICSTIAEYSRQCIRNGGTPGNWRTQELC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--KT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNLEY
NECGPSCRD-----SCSNPERGSICENRCVEGCFCPS---G---------MVLDDIEYL-
---GCINLTE

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACTYNGNVFLPGANYSTSCSSCTCSGGKWNCKDTPCSST

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CSIEGGSHVT
TFDVTHFTVYGDCTYVLS-KVCDDENFIVLGELRPCGRKDTETCLMEVIIILNSGQTVTI
EVRSTGEVYVNFLY--TILPISSGPFTMLQPSPFYIVFDY-VDGMQAIIQLVP-VMQLYV
VLDPKYKTKTC-----GICGNFNDIQGDDFLTISGVIEGSAA-AFV------NTWKTDAN
CPSVKTVLEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CALS
LE-N

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1461)

EDYAKHWCSLLT-DSESVFSQCHYVVNPNVFYKNCLSDTCSCENSEECMCAALFSY
VRACAAKDVILTDWNS-FVCTNYRSVCSNNQVFSYTISSCLPTCGSLSL-SDSMCEIYFD
PLMGCSCGKGLYLDDDGKCVPPSLCPCYYRGSPIQSGTTINEGGVICTCTQGKLNCTGNE
---IS---DCVDPMVYISCKNATPGTPGAE-CFKSCETLD---MHC--YSKRCIPGCVCP
NGLVFDGKGGCIR-DTDCPCIHNEAMYAPGDEIKIRCNT-------C----VCKDRMWNC
TENVCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1877)

CKVYGDGHYSTFDGQIYSFGGECEYTLAKD--HCSSNDT-GSTFRVITENIP
CGTTGTTCSKSIKIFLN-----------------------------------GYELVLLD
DHLNVIQRG-NDTKVPYRVRLMGIYMVIETNQGLLLVWDKRTTIYIKVTNIFQGMLCGLC
GNYDGNRNNDFTTRTN

ENSGT00760000118896_5_Linker_20_26 (1877, 1919)

AVVGNV-------EEFANSWKLSLACPDAKLNKDPCALNPYR

PF08742 // ENSGT00760000118896_5_Domain_26 (1919, 1996)

MA
WAQKQCSIIYSGVFAACHP--HVDPSPYYDACVSDTCACNTGGDCECFCTAVAAYSQACG
EFFICIYWR-TPTICPMFCDYYNKEKRCEWHYRSCGAPCLKTCRNPSGKCSYELGGLE--
-VGCYPKCPKDAP--YFDEDDMECVS--KCGC---------LDEDRVY------YKL-GS
QMPSNETCFTCY--------CTE-NGPMCSPNAK----ACVCIYEGRMYNYNQTIYSTTD
GMGGCITAICKENGTIHRDVSPCLSTLT---P---PFTFSTV--PT--TE---------P
TESNSKIHPS--------------PS--------------PPSLYS----VSLPFNIII-
------TNNSSSCRHGLNAFFTLLSA--RTKV----------------------------
------------------------------------------------------------
----------TKMTTTLCVF----------------------------------------
----------------------------------------------------------EQ
CEWSQWFDVSNPATQ-NGDDDETYQNIRNNGYNICENPK---DIHCEADNSSTVPFG-LK
NNIICNVSIGLFCNNSNQPP--DVTCLNYQIQVLCCSFVP--CELLTSTESPSTTSYLTS
TKV--------------KTTTQTSATSHTTTTHTT------------KKSTQLSTVHT-S
TTSISPTASTLTSK----------------------------------------------
-----------STSHTTKLAS--------------------------TVPSTKIE-----
---------------------------------TTKKTSA------------RTPISGTE
RLP-----YSSVSYSTSVFCSPGCYWSPWFNLNSPSPGISDGDFENLKSIQSV--AQICT
NP---DDIECRAVMFPNTSLNELGQ-N-VICDVSDG-LQCLNMDQT----SQMCYD---Y
-EIRFHCCDDYSKCITTPQLPTETT-HKTTSLSPHVTTTTLTK---KSTI--------LS
SLSTH-----------RTSISPTASRLTSKSTSHTTVHTTST-----PTTVKP-------
-VKTSTHI--PSVTSVHTTSTPATTGAISST---------------VKPAKTSTH-TT--
SV-HTTTT------------PAPTGA-----------I-S------STVKPVKTS-----
--------------TH----------TT----SVTSVHATTTPATTGAI-----------
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--------------------------------------------V

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGRFHFKTFDG
AVFRFPGLCNYVLAAHCRAAYEDFNVQLRRALLGETP-TIGRIVVRTEGTVVEVSPGAIL
ING---------LREPLPYSRSGVTVETSSGYVRVTVRTVLTLL-WN-GD---DGAL---
----LELDAKYANRTCGLCGDFNGLS

ENSGT00760000118896_5_Linker_0_4 (267, 331)

TYNEFYSN-----N----VRLTTWQFGNLQKLDG
PNEQCEDATSSP-TSNCT--D---------

PF08742 // ENSGT00760000118896_5_Domain_4 (331, 408)

EESSCLSVLNGPAFAGCHQLVDPRPYVEAC
MQDLCGCQEA---N--QSSCLCATFSEYSRQCAHAGGQPLNWRSQNL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CG--KT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPSNMQY
HECGSPCVD-----SCSNPEQSQLCEDHCVDGCFCPP---GKPVLPVSVGTVLDDIEGQ-
---GCVPLSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTHKGQSYKPGGSFSTPCRTCTCLSGLWHCEELPCPGM

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVDGGSHIT
TFDQKRYNIHGDCSYVLS-KKCADAAFTILGELRKCGLTDNENCLKSVTLNLHGGETV-I
RVQSNGAVFVNSIY--SQLPISAANITVFQPSTYFVLVHAAF-GLLLQIQLVP-IMQVSV
QLDPSFRGQMC-----GLCGNFNQNQADDFTAISGVVEGTGA-AFA------NTWKTQAD
CANVKNSFENP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1459)

NYAQHWCSLLT-DPNGTFSQCHSIVSPAPYYKNCMFDTCNCEKSEDCLCAALSSY
VRACAARGVVLSGWRA-R

ENSGT00760000118896_5_Linker_14_15 (1459, 1467)

VCTKYMDS

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPSSLSYSYVVESCQRTCRSLSE-PDVTCSVRFS
PLDGCVCPGDTYLSEEGRCVPAAQ

ENSGT00760000118896_5_Linker_15_17 (1525, 1588)

CPCYFKGSLVALGETVQENGVVCSCSGGKLSCFGAT
DD-SP---VCRAPMIYLDCSNASAGTP

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GAA-CQKSCDTLD---VAC--YNTQCVPGCVCP
NGLVKDGHDRCVK-AEDCPCVHNEASYQSGETIRVDCNN-------C----TCRNRRWEC
TQALCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CSVYGDGHFITFDGERYAFEGNCEYSLAQD--YCGGSPGTNGSFRVITENIP
CGTTGVTCSKAIKVFLG-----------------------------------GTELIFNE
GVVKVVERA-LGEEVPYKLHSRGIYLVLETLAGLVLMWDRKTSIFIKLQPRHKGKVCGLC
GNYDGNSVNDFTTR

ENSGT00760000118896_5_Linker_20_26 (1875, 1920)

SLSVVGDV-------QEFGNSWKISPSCPDAASPRDPCTANPYRK

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1999)

A
WAQKQCSLINSDVFAACHS--QVDATKYYEACVSDACACDSGGDCECFCTAVAAYAQACN
DVGVCVSWR-KPR--PMFCDFYNPHGECDWHYQPCGAPCLKTCRNPSGKCLVNLPGLE--
--GCYPNCPAEKP--FFSEDEMKCVD--QCGC---------YDEDGNY------YKV-GD
RVTSLANCQSW---------------------------YCTCLYEGHTYHFHEVIYNTTD
GLGACLIAICGDNGEIKRMSEDCPVTPSTT-V---PFTFTTS--GV-----PRST-AALT
--------------------------------------------------------S---
------------------RI-WSTP------T----------------------------
------------------------------------------------------------
----------GA------------------------------------------------
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------------------------------------------------------------
-------------NTTSVACQPRCEWSEWFDTDYPKSGAFGGDIETYDKIRSTG-KTFCQ
KP---LEIQCQAENFPNIPIEKLGQ-V-VFCDVHYG-LICNNKEQP--GLFKICQN---Y
-KIRVLCCDDSHCIGKTSA-TPPAPT---PQLTTSLGTGTTAQLPLTTIP-LVTESSPAT
TATQQSTGSPPSPTR--TTT-----------------------------TASP-------
-STSTSAP--PTP----------NT-A-----------------------IGS-TARTS-
RS--TGSP------------PSPTRT-----------T--------TTASPSITT-----
--------------TTAS--PSTSTSAP----PTPN-------TAIG-------------
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---------------------------------------AHNGYV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 285)

CST-WGNTYFKALDG
DIFYFPGQCNYLFASNCKSVTEEFNIQIRRSVVNGLP-TVSHIGMIIEGVFIELTKDTIT
FNSQV---------VDLPYSLSGIQVDRLGPYIRVISKAGLEFK-WN-ED---DAAM---
----LELDPKFQNQTCGLCGDFNGIPVYNEF---------MFNS

ENSGT00760000118896_5_Linker_0_4 (285, 317)

VRLTDNQYGNLQKMNG
PTETCADVLEVP-QDN

PF08742 // ENSGT00760000118896_5_Domain_4 (317, 409)

CTDL-----------SNICHVVLSSAAFSSCNSLVDPSPYINVC
VQDLCRCSSN---A--TGFCLCNTFTEYSRQCAHAGGVPSNWRNANLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--LQ

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CNYNMEY
SECGTSCPD-----TCTYPDRSLSCDRHCTDGCFCPA---G---------TLWDDIGNS-
---GCIPSSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CSCVYNGQVYNSGSTYFAQCQSCTCVRGKWQCVDQDCTGS

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 696)

CSVVGGSHIT
TFDFNRYNFFGDCSYVLT-K-TSDNQFSVVGELMKCELKDTTTCLKSIVISLEYGNE-VI
EIQPTGSVDVNGIY--SQLPVSSASVTIFQPASFFIIVQTAI-GLQVEIQLGS-VMQVYI
YLDPKWRAQVY-----GLCGDYNNVQMDDFKVLSGVIEGTAA-SFG------NTWKTQAS
CPNVISHFDDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-N

PF08742 // ENSGT00760000118896_5_Domain_14 (1385, 1461)

ANYAQFWCSKLT-DPAGPFATCHSTVDPQLYKTNCMFDSCNYANSEDYMCAALSAY
VHACARVGVAITGWRD-SSCNAS-TTCQSSLTYNYYVTSCQPTCRSLSE-PDVTCDINFV
PVDGCVCTDGTFLNEQGVCVPREQCPCYFRGKIVNSGETVRELGALCTCSLGKLDCIGHL
NL-SK---V

PF01826 // ENSGT00760000118896_5_Domain_17 (1570, 1638)

CSGSKVYFDCNNQNATATGVE-CEKSCQTLD---MNC--YSAQCVSGCMCP
NGYVANGTDGCIL-EEQCPCIYNNDPYDEGATIRASCRT-------C----TCQNRMWYC
TGETCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1877)

CAVYGDGHYYTFDSNRYGFSGDCQYVLAQNKDYC--SDPNNGTFRIITENIP
CGSTGTTCSKSIRFYLG-----------------------------------NNVLILSE
GKFEVQYTGSG-TYVPYKVHQMGIFLVVETLNGIVLVWDKKTSIYIKLQPQFQGKTCGLC
GNYDGNSINDFTTRSL

ENSGT00760000118896_5_Linker_20_26 (1877, 1919)

SVVSDV-------LEFGDSWKQSTSCPAPLAIGDSCAANTYR

PF08742 // ENSGT00760000118896_5_Domain_26 (1919, 1996)

KP
WAEKKCSVIIGTTFAACHAV--VNPNPYYSTCVNDACACDTGGDCECLCTAIAAYAQACS
EAGACVSWR-TPDFCPLFCDYYNLDGQCEWHYQACGAPCMKTCRNPTGLCYYNLMGLE--
--GTKQPEPLTFS--LLGPGTLHCTL--FC-TL------QL---QSSPINLDFHFPPLTP
-IYLQEKCISRI--------CFH-KTTSCASNAG----SDCCDYDNTKYTTTQPIYCTSD
GLGGSVHAICE-NGTITRYATDTPCTTTTT--------------PVTTTSVT--TVT--S
TPPDCYSHPT--------------------------------------------------
--------DGVTP----NGDSATSPD---V------------------------------
------------------------------------------------------------
----------SPYTNQDIVPS---------------------------------------
--------------------------------------------------------EAPI
CTLTPWIDVSYPVYGG-TGDDESFDNIRRHGISICNDTMSIVSVDCRAKDFPSASLQDLS
QTITCNTEVGLICLNTDNF---P-KCDNYEIQIQCCSPNTATEPTTKTPR------STTT
C-S---------------MHTTTISSVCPVLS----------------GKRHTWSVTL-S
KVPEAVRIGLHFGG----------------------------------------------
-----------TAESR---LGP-------GCT--ENVLVDSPGIEPTPPDTSPQPHP--T
---------------------------TTSLSVTT-------------------------
-VTHTRTHACTTPSSRLVTSPPICTVTPWIDVSYPVYGG-TGDDESFDNIRSHG-ISICN
DTMTVVSVDCRAKDFPSASLQDLGQ-T-ITCNTEVG-LICLNSDNF-----PKCDN---Y
-EIQIHCCTINSGTTTETTETVPETTTCSM--TTT-----TTTSSH-T-------TS---
---THVT------ITST-S---------------------GT-----TTSTVP-------
-STSVS------------------------------------------------------
-------------------------------------TSS------TSSIPTTTLL----
---------STTISTISTETTSEPTTSL----SSTTFSTITTSTRCYCQPQRYVGPCTTT
TVTTPSSTE-----------------------------------TSPTT-AT----PTTT
-CLMWMPTTPGSS-----------------------------------------------
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----MGAPSACRTLVLALAAVLVVPQPSP-------------------------------
--------TGAPTSSPTRRVSFVPPVTVFP--SLSPLNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFHFPGLCNYVFSEHCGVAYEDFNVQLRRGLVGSRP-VVTRVVIKAQGLVLEASNGSVL
INGQR---------EELPYSRTGLLVEQSGDYVKVSIRLVLTFL-WN-GE---DSAL---
----LELDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 339)

TFNEF---------YAHNARLTPLQFGNLQKLDG
PTEQCPDPLPLP-AGNCTDE-----------EGICHRT

PF08742 // ENSGT00760000118896_5_Domain_4 (339, 408)

LLGPAFAECHTLVDSAAYLAAC
AQDLCRC------P----TCPCATFVEYSRQCAHAGGQPRNWRRPEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCAD-----TCSNPQRAQLCEDHCVDGCFCPPG------------TVLDDITHS-
---GCLPLGQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHSGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KKCADGSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA-I
RVQADGSVFLNSIY--TQLPLSAANITLFTPSSFFIVVQTGL-GLQLLVQLVP-LMQVFV
RLDSAHQGQMC-----GLCGNFNQNQADDFTALSGVVEATGA-AFA------NTWKAQAA
CANARNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPNGAFSRCHSVINPKPFHSNCMFDTCNCERSEDCLCAALSSY
VHACAAKGVQLSGWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKYMQN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQRYAYVVDACQPTCRGLSE-ADVTCSVSFV
PVDGCTCPAGTFLNDAGACVPAQECPCYVHGTVLAPGEVVHDEGAVCSCTGGKLSCLGAS
LQKST---GCTAPMVYLDCSNSSAGTPGAE-CLRSCHTLD---VGC--FSTHCVSGCVCP
PGLVSDGSGGCIA-EEDCPCVHNEATYKPGETIRVDCNT-------C----TCRNRRWEC
SHRLCLGT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1875)

CVAYGDGHFITFDGERYSFEGSCEYILAQD--YCGDNT-THGTFRIVTENIP
CGTTGTTCSKAIKLFVE-----------------------------------SYELILQE
GTFKAVVRG-PGGDPPYKIRYMGIFLVIETR-GMAVSWDRKTSVFIRLHQDYKGRVCGLC
GNFDDNAINDFATR

ENSGT00760000118896_5_Linker_20_26 (1875, 1925)

SRSVVGDA-------LEFGNSWKLSPSCPDALVPKDPCTANPFRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSILHGPTFAACRS--QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH
DAGLCVSWR-TPDTCPLFCDFYNPHGSCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLE--
--GEG------QP--FLDGASY--------------------------------------
------------------------------------------------------------
-----------------------------------------P--WVP-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------E
CMWGARDPQGR-----SVGS----------------------------------------
-----HK-----------------------------------LHNASLEGSSPQP-----
----------------------------------------------------SFSAST-E
RAVPTPT-----------------------------------------------------
Q-----TT---ATEKTTLWVTP-------------------------SVQSTAA------
----------------------------------------------------LTSQAGSS
SGPVTV----TPLAPGTTTCQPRC

PF13330 // ENSGT00760000118896_5_Domain_29 (2905, 3007)

QWTEWFDEDYPKSEQLGGDVESYDKIKAAG-GHLCQ
QP---KDIECQAESFPNWTLAQVGQ-K-VHCDVRFG-LVCRNWEQE--GVFKMCYN---Y
-RIRVL

ENSGT00760000118896_5_Linker_29_33 (3007, 3294)

CCS-ADHCRGRATTPPPATEPE--------------------------------
-----------------TATT--TTTQALFSTPQPASSPGVTRAPLPSTTAVP-------
-TLSKGLTS-P-----------RYTSTLGTATTGGPTVPAASTEP-TVPGVATSSLPTR-
SALPATTGSSGTWRPSQPSTLATTTMATSRAHPTG--TAS-T----GSKEPLTTSLAPT-
-------L-TSKLSTSRADTSTPRAETT----LTPLTEATTSQGTTRCQP-KC

PF13330 // ENSGT00760000118896_5_Domain_33 (3294, 3391)

EWT-EWF
DVDFPTSGVAGGDMETFENIKA-AGGKMCWAP-K---SIECRAENYPEV-SIDQVGQVLT
-CSLETGLTCKNEDQTGRFNMCFNYNVRVL

ENSGT00760000118896_5_Linker_33_35 (3391, 3639)

CCDDYSHCPSTAAPTP-TSSTQAPKLTSTG
ATTGATTP--TVTASTA----------------------TTAMVATTPT-----------
--------------------------------------------ATATWSTKSPAVTGPS
TLATTQTGPSFSKTTERVPLPSPSAPPASTTSLLPTRGQQTSQAPSMPTSPTVASTPTTS
PMVTDRVHTTLQTSSSGPIRTTLPSGPPSPSTGCVPRC

PF13330 // ENSGT00760000118896_5_Domain_35 (3639, 3737)

TWT-DWFDEDYP-SPGPDSGDF
ETF---------------GVIRSAG----------HTFCEHPQDI-ECRSEMAPDQP---
LEALGQVVQCDVSIGLTPKMLTTTTTTTVAASSTATPFATVQTAHTPKVLTTTATTTGST
VTPSNSPGTASTLPALI-----TTTTTPTTTVSMVTPSSIPGTTHTPAVLITTTMTTMGT
GSTATPTSSPQTAGTPTELTTTATKITA---------TGSTTTPSSTPRTTPIPLVWNTT
AITPAAPS-------TAGT-----------------------------------------
------------------------------------------------------------
-----------------------------TNTLPVLTTTS--TT--HGQSLPPSSPHTVP
TVWTSV--A---TLGTTHITEPSTVTSHTPAGTTGTTLHSTPALSSPHPSS------RAT
ESP-PPGKTTLGLTTATSRTTATTTPSETRISTLLPSS-PTSAPTTPAVTTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_37 (4199, 4292)

WS
DWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ-PL---GLECRAQAQPGVPLRELGQIV
ECSLDFGLVCRNREQVGKFKMCFNY-EIRVFCCN-YSL--CPSTPASSSTATPSSTP---
------------------------------------------------------------
------------------------------------------------------GTTWLL
TELTTTATTT--------------------------------------------------
---------------------------------------AATG-----------------
--------STATPSSTPGTTWILT------------------------------EPTTTA
TTTVATGSMATASSTLATAGTPKV-------------------------------TTTAR
TPTVTG--SKATP---SSSPGT--------------------------------------
---------------------------------ATTLPAL-TSTATTPTAT---------
-------------SFTAIPS----------------------------------------
----------------------------SSLGSTWT------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------RL---SQT------TTPTATMTTAR-------------------------
------------------------------------------------------PSSTPE
TAHTSTVLTTTATTTGT--------TGSAATP-SSTP-----------------------
---------GTAHT----------SKVLTT--ASTGLTATASSSPGTAP-----------
------------------------------------------------------------
------TLPVR-------------------------------------------------
-----------------------------------------ISTTTTPTTSGSTVNPSSI
PGTTHTPAVLTTTTTTVAT-GS-----MATPSSST------------------QTTATPP
PLTTRVTTITAT--GSTTTPSST-PGTT---PIPPVPI-TTATTHGRS---LPPSSPHTV
PTAWTSVATSGTTHGRS---------------------LPPSSPHTVPTAWTSVA--TSG
TTHITEPSTVTSHTPAGTTGTTLHSTPALSSPHPSSRATKSPPSPGKTTLGLTTATS--S
TTA--TPSETPTSTLLPS--------SPTS------APTTPAVTTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WS------
DWLDYSYPMPGP-SGGDFDTYSNIRA-AGGAVCEQPL---GLECR-AQAQPGVPLRELGQ
IVECS-----------LDFGLVCRNREQVGKFKMCFNYEIRVFCCNY-------------
-----SL-CPSTPASSS--TAT-----------PSSTRGTT-WPLTELTTTATT-----T
AAAGSI------------------------------------------------------
--------------------------------------------------------ATPS
STPGT-------------------------------------------------------
------------------------------------------------------------
-------------------TWILTEPTT-TATTTVATGSTA-------------------
--------------------------------------TPSSTPGTTWILTEPTTT----
------------------------AITTVLTPPKVLTST---------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------A
T-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------TPIASSSKATPSSSAR--------------------------
----------------------TTTTL-PVLTSTATKSTATSFTPIPSSTLWTTWTLPAQ
TTPMATMST-----------IHT-------------------------------------
--------------------------------------------------SSTP------
----------------------------------------------E-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TTHTST-----------------------------------------------
----------------------------------------VLT-----------------
---------------------------------------TTA------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------TTTRATSSMATSSSTLGTTWVLTELTTA-
A-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--TTTAATGSTATPSSTPGTTWILTEPSTTATMTV-------------------------
----------------PSGSMATASSTPGTAHTPKVVTTMATMPTATGSTVPSSSTLGT-
-----------------THTPA----------V-LPS-SLP-TFSMSTVSSS-VL---TT
LRP---TGLPSSHFS-TPCFCRP-L----AFSLLAMLVPHWPHLAPPGHTRSPLATLGPH
WPQCIPTGHNASPVATFSPHWPQCVPTGHIRSPRPQSVPTGHNRSPLATISPHWPHSVSP
GHNASPLATVHPHWPHSVSPGHNASPLATISPHWTHSASALPTPLPGTAAPSCTDLCVHS
PRTLAWEVIYN------KTD--------RAGCHFYAVCNQHCDIDRFQ-GACPTSPAPVS
ST----------PL----------------------------------------------
------------------------------------------SSPSPAPGCDNAIPPRQV
DEAAEAPGLQWLPEVAVT-VVMLAAMT--P------------GERGHHHGACQPVHLCPT
G-----------------I

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9893)

CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLY
LDNNYCAASA--A-AASCPRALSIHYKSMDIVLTV-TM-VHGKEEGLTLFDKIPVSSGFS
KNGVLVSVTGTTTMRVDIPALGVSITFDGHVFQARLPHSLFHNNTEGQCGEWAAGPVRG-
-----------------------------RAAAGPDNPPQPSPSTQPR------------
--PSPP---QPHTSPPPAPPT------------LSPAL---------HPFIS--------
---------------------FPAPQCPSWGLT------------------------WMT
VEASWISRNQNPQ--------L-----EGLAEGCFCPEDQILFNTHTGICV-QA-C----
-PLRDPL-DPFQPGERWVSNCQSCVCDEGSVSVQCKPLPCEAQGQPLPCSRPGFVTVTRP
RADNPCCPETVCVCDTTTCP-QSLPVCPPGQELICTQEEGDCCPTFRCRP--QL

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CSYNGT
------FYGVGANFPGA-LPCHTCTCLSGD---TQDPTVQCQEDACNNTTCPQGFEYKRV
AGQCCGECMQTACLTPDG------QPVQLN----ETWVNSRVDNCTVYLCEVEGGVHLLT
PQ--PASCPDV--S-----SCRGSLRKTGCCYSCE-E--D----------SCQVRVNMTV
LWHQGCKT--EVNITFCEGSCPG-VSKYLAEAQAMQHQCTCCQERRVHEETVPLRCPDGS
AILHTYTHVDECGCTPFCVPAPRAPPHTPGFLAQ--------EATAV-------------
-----------

------------------------------------------------------------
-----------------RGMSFLPPLRTAP--VVRARNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGDFHYKTFDG
DIFRFPGRCNYVLSAHCGAVYEDFNVQLRRGGESNAT-TVTAVTMKLDGMVIQLTKGSIL
VNG---------RPTQPPFSQSGVLIEVSNGYLKVDAKLGLILM-WS-PD---DSLL---
----LELDPKFANQTCGLCGDFNGQ

ENSGT00760000118896_5_Linker_0_4 (266, 335)

PVFNEF---------LSHGVKLTALEYGNLQKMDG
PTEQCQDPVPVP-PTDCG-HG---------T-GP

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 409)

CEEILTGQLFSGCRALLDAGSYVQAC
RLDLCLCEHA---D--RTRCICPTLAEYARQCAHAGGLPPDWRSPHLC

ENSGT00760000118896_5_Linker_4_5 (409, 414)

P--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPPSMQH
RECGSPCAD-----TCSNPEHSQLCEDHCVDGCFCPE---G---------TVLDDIGQT-
---GCIPASQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCVYNGATYAPGTSYATDCTNCTCSRGQWSCRELPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CAVLGGAHIS
TFDERQYTVHGDCSYVLA-KPCDSSVFTVLGELRRCGLTDTETCLKSLTLSLDGGHTV-V
TVKASGEVFVNQIY--TQMPVSAANVTLFRPSTFFIVAQTKL-GLQLTIQLVP-VMQVFV
RLGPELRGLTC-----GLCGNFNQNQADDFRTLSGVVEGTAA-AFA------NTWKTQAS
CPNVKNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NE

PF08742 // ENSGT00760000118896_5_Domain_14 (1386, 1460)

RYAQRWCSRLT-DPRGPFAQCHVAVNPGTFYSNCMFDTCNCEKSEDCLCAALSSY
VHACASKGVLLRGWRD-GV

ENSGT00760000118896_5_Linker_14_15 (1460, 1467)

CAKPMAT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSLTYQYSISTCQPTCRARSH-EDITCGISFV
PVDGCTCPNGTFLDEAGKCVPATS

ENSGT00760000118896_5_Linker_15_17 (1525, 1588)

CPCYHEGSVVPNGESLHERGVICTCTQGTLTCIGGQ
VP-TP---VCTPPMVFLDCRNATPGAS

PF01826 // ENSGT00760000118896_5_Domain_17 (1588, 1638)

GAG-CQKSCFTLD---MDC--YSPQCEPGCVCP
DGLVADGEGRCVA-PTDCPCVHNEASYLPGQTIRVGCNT-------C----TCENRKWRC
TEEPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1874)

CAVYGDGHYVTFDGRRYSFSGDCGYTLLQD--HCRGNDT-TGTFRVVSENVP
CGTTGVTCSKAIKLFLG-----------------------------------SFELRLSE
GRVEVLERG-VGQEPPYSIRQMGIYLVVDTEAGLVLLWDRKTSIFLKLSPEFKGRVCGLC
GNFDDKAINDFTT

ENSGT00760000118896_5_Linker_20_26 (1874, 1920)

RGQSVVGSA-------LEFGNSWKFSPACPDAPAPRDPCTANPYRK

PF08742 // ENSGT00760000118896_5_Domain_26 (1920, 1996)

S
WAQKQCSIINSATFAACHA--HVEPTKYYEACVGDACACDSGGDCECFCTAVAAYAQACH
DVGVCVSWR-TPDTCPLFCDYYNPEGQCEWHYQPCGAPCMRTCRNPGGRCLHDLPGLE--
--GCYPKCPPAAP--IFDEDQMQCVA--TCPT---PPPPLPCRVRGKS------YRP-GT
VVPSDQNCHSCI--------CTE-NGVQCAYDSE----ACVCIYDGRHFRPGDVIYHTTD
GTGGCLSARCSANGTIERGVSPCSATSPA--P---PTTFSFS--TSAPGT----------
------------------------------------------------------------
-----------------------------TPG----------------------------
------------------------------------------------------------
----------TTVQPHQACG----------------------------------------
----------------------------------------------------------EE
CQWSPWLDISRPGRGTDSGDFDTLENLRAHGYQVCAAPK---KVECQAEEAPGVPLQVLG
QHVECSPTVGLTCYNHKQTS--G-LCHNYQIRILCCFPRT--CSPSSSPAQTTPPAASGN
TET--------------GPT--R-EVSGVSSVP-----------------TE-HKISP-A
TV---AATGTSILS----------------------------------------------
-----------TTS-----ET--------------------------PAPGATVPVQA--
---------PGT--TT--TPPGTPTP--APGTTTAPPGTP------------TPALEKTT
LLT---LTPMPISTTHEPCLKQLCTWTHWIDSSYPEPGINSGDFDTFPNLRAKG-YKFCA
KP---NNVECRAEFFPNVPLEELGQ-D-LICDKNVG-LLCLNKNQL----PPICYN---Y
-AIRIECCEQVDVCTSTPHAGSSEVTH-------P-------------------------
----------IPRDTETQTQLTRNTGVPSSPTQHGIA-----------------------
------------------------------------------------------------
---------------------------------------S------SAPV----------
-----------------------KPAAS----TTPNTYRVSSPVTVTCQP-QCTWT-KWF
DVDFPSPGPHGGDVESFSNIMR-RGEKICHRP-EYISRLECRAESHPEV-SIEKLGQVVQ
-CDLSKGLVCRNRDQAGNVGMCLNYEVRVLCCEPPEHCTTHKTVTV-PHTPSMSPTNLT-
---------------------------------ETTVHLVTSHSTSVP------------
------------------------------------------------------------
------------------------------------------------------------
--------------TSSLTKV---------------------------------------
-------------------PETS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---STPVPTTSPRSVPETSSTSVSTTSPTSVPE----TSSTSVPTTSPTSVPETSSTTVP
A------------------------------------------SSP----T---------
----------------------------------------S--------VPTTS------
---STTVSWTSPTSVPPTG----------TTSAPTA------------------------
------STTPVHTH------EATHSPPVTVT------------CQPRCTWT---------
---------------------------------------KCEATHSPPVTVTCQPRCTWT
KWFDVDFPSPGPHGGDVESFSNIMRRGEKICRR-PEYISRLECRAESHPEVSIEKLGQVV
QCDLSKGLVCRNRDQGGNVGMCLNY-EVRVLCCE-LP-EHCGHTSVTPSSAPPEHTS---
-VVSSVPWPSSTAPASTTC-----------FCSVSASPSGPTPGPPGWPSPSLEG----T
GQASPSAVPTGPY------------RMPAPSRP---F-----SRSLVTAGAPGLVGYKQT
SPN-NHAP----------------------------------------------------
------------V--LLGTPRNSTS-----------HNTGRAGPQGGTTH----S--TVS
TNNGPGTPRTTGASAAPGATSTTR----------------------PLTATSSAS-PAGA
TTSCPRTAVPRT-RTSTCSCAAAW------------------------------PAPGP-
----------PSP-TLSSRPRGWCWRPPTAP-SSSTGG-GEPGAGCGGAGTLGVA-----
---RDVRGVG-VSLPALGAGEAGGGRLPPHPARPG---LCGVQQAGGPDCVCGRLYPGPV
PVPLLPVCHLRRVL--S-PVR--PCGGAAPGLEGPRPLPSAPPACGTRSAAR--------
--PAPTPAL--------TPSAPS-----SARTTVWTAASAPQAGSPGPTPWLPRVGPTSP
PTTRGSTTCTGTAATSCPRCGSGHPDPGQRRGVRELHLHPAARVCRTPAPSAWRTVLPPS
YLGCVWELELP-SPLALGWVGLGDPTSGRVSCVAGRLSCLGAAEQRSSGTAGGYAATSPA
WAPAWPMGTV---------------------------TSSPSTGSAMASRGPVSTRWSSR
AHPDPARRRT---TVGATARPTGPSASSPRTSPA-GPRA----LPARR----PSSSSWRA
--ASAGCAGTSTTTPSTTSPRAASPWWAAP-------------WSSATAGSSPRPAPTPR
PPATPA-----PPTRTASPGPRSSAASSTAR--PSPPATLSRASRAPGTGGSPPRLRPEV
LPVTFSR---------------------TR--LPAHKGLSPHPEDTSRVMTA-------V
G--RAVSTRASAQPAASGAHTASQVRPRGGPGDGAGAEGCEGPRPRPTGSVPTVTTVCV-
-REFC-LWSDWYDSGPPEPGMAGGDFETFVNLRQ---KGYEVCLAPVSVECRARR-----
LPDT-----PLLQLGQKVECD---------------------------VAWG-LTCFN--
--SEQSPPLCHDYELRVLCCSYL----PCGSSPGA------------------TTTALG-
----------------TTTS----PGAT---T--------------------T--A-LGT
TTSPRAASW--------------------------------QP-----------------
----------------------------------------------LARST---------
------PATE--TPPAETTV------TG----TWASSSSPALATTSCQPRSTP-------
--------SLRR-PGGTL------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------SRT
TRSGAQEG------PFASSLW---TSSARPRTS---------------------------
------------------------------------------------------------
--------------------------------------------------PA-GALRSWA
SACTATSILA--------------------------------------------------
------------------------------------CQDQCAGPTPGAQ-TL--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------ATAQTTG-GPSRETPQTHT---------------TGT
VPAGPPS-----------------------------------------------------
-----------------------S----------------------PRT----------E
PRT---T-------AARMS---PGTLGT----ATTAATPSQSTAGCQPQCEWTDWFDVDF
PTSGVEGGDLETLDNIRAAGGTLCEEP----QKIECRAENYPEVSI---DQIGQVLSCDL
HTGLVCKNQDQKGPFNMCF---NYNIRVLCCRPSPHCPSTPAPGGSTSLGQGVPV-----
------STTQTLPSPART----------------PERV----------------------
---------SS-----PGPY--------------ASPGT---------------------
------------------------------------------------------------
------------------PTTTTTKP--------T-------S-----------------
-------------------PRAPTTAPE--VTSRPWTSPGSPPS----------------
---------------------TATAPEPTTP--------------SRGTPVPEI------
-----------------------------------------------------------T
SSPPGTTVGLSTAASRA-------------------------------------------
---TVPTGKTETSPP-------------VTSS----HT--------QT-PTSPM------
------------------------------------------------------------
-----------------------AKSTACEPRCAWTDWLDESYPAPG---ASGGDFETYA
NLRAMGKAICQQPR----ALQCRAEAQPETPLEELGQVVRCGLEDGLVCRNQDQAGPFHM
CLNYQVRVLCCEGDGHCTSTLATTALSS----RGAG------------------------
------------LGPTPVL-----------------------------------PT----
-------------------------STMV---------PSPPAPS-----TGRT------
--------TNT------ATCRPTCRWTDWLDSDQPRAG----------------------
--------------------------------------RYGGDIETYYH-----------
-IRDAGGQLCAEPE--A-------------IE-CQAVLYPDVPWEQLG-------QDVRC
DVNYGLICRNNWQTGGRTCL-------------NYRVRVLCCDGPGHCAT----------
---------------------------------------QPSTEPAAASSSS--------
----------------------------TRPT----------------------------
--------------------------------------------SSG-------------
-------------------------------------------VTRLQTTATLP----SS
-----L------------------------------------------------------
---------------------KTTTTHP----N---------------SPETT-------
------------------QR-------------------------------YT-------
-----------------VSTTQIS-P-ASHRT----------------------------
----------TQMG----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------PSSAG--TTQGGP-
-----------------VSTTQ----------I-SPA-SSR-TMTVSTSPMS-VL---TT
PGP---PV-SSRGNLTTRCFCRA-L----GQL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--FSPGDIVYN------KTD--------GAGCSFYAVCSQHCDIDR-FQDACPTSPPPEA
SST---------PA----------------------------------------------
------------------------------------------ASPSQPQGCDLLIPPRQV
NESWTLPDCTVARCEGHN-HVVLLGR--KPVASIHCVNGHPPVRVSQDNEPCD-FHFECE
C-----------------S

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGGSHYTTFDGTTYSFADNCTHVLMKEIRPRYGNLSIS
MNGYYCGAA---AAAAPCPRALSVHYKSMEVILTTHTG-AHGQEQSLILFDQTQVGSGFS
KNGVSVSVAGATAMTIDIAAAGVSVTFDGQVFHIQLSYSRFSHNTEGQCGTCTNSRTDDC
RRPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9979)

TMAATCQDMAHHWLVPE----SGREGCLAPTRPPSTAGTSPSA------------
--PTTP---ASSPCPPA-

PF08742 // ENSGT00760000118896_5_Domain_57 (9979, 10054)

PLCE--LL-------QSPLFAECHALIPPDPFVSSCVSDGCQ
AD---DPRAPCRSLEAYAALCRARGVCSDWRNA

ENSGT00760000118896_5_Linker_57_59 (10054, 10064)

TNGLC--DVT

PF01826 // ENSGT00760000118896_5_Domain_59 (10064, 10143)

CPPDKVY----RPCGPA
QPASCDSRSPS-------------GGGKGLAEGCFCPDGLTLFNTHTDVCV-RA-C----
-ACVGPDGFPKSPGERWVSNCQACLCHEGSMSVRCAPVPCEPQERPPQCGRAGFVTETRP
LANNSCCLETLCVCNTTTCP-QSPPRCRPGEELIRTQKEGDCCPTFICRP--LLCYYNQT
------AFGIGATFPSL-TPCHTCTCLPGD---SQGPTVRCEEDTCN-TTCSPGSEYRKV
DGQCCGECVQTACPTE-DG-----QLVQPS----ETWVNSLVDNCTEYRCQVRNGLHVLI
TR--ATPCA--NMS-----SCQGILRKTGCCFSCE-E--VVRP------DQCQVHVNRTI
LTHQGCATQAPVNVTFCGGSCPG-LSKYSTEAQAMERQCTCCRETEAHEEVVTLRCPDGT
AVRRTYTHVDKCSCAPACVHSPKVPEDSTPILLT--------------------------
-----------

------------------------------------------------------------
---------------------------------------------

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 268)

CST-WGNFHYKTFDG
QVFYFPGLCNYVFSEHCGAAYEDFNIQLRRGLESNST-TLSRVIMKLDGLVVELTKSSVL
VNN---------HPVQLPFSQSGVLIELSNGYLKVVARLGLVFM-WN-DD---DSLL---
----LELDTKYANKTCGLCGDFNGSPE

ENSGT00760000118896_5_Linker_0_4 (268, 335)

SSEF---------LSHNVRLTPLEFGNFQKMDG
PTEQCQDPLPVP-QKNCS-I------------SI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CEEILKGQLFSNCAALVDISSYLEAC
QQDLCLCESS---D--PSNCICHTLAEYSRQCAHAGGQPQNWRGPNL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--QT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CLLNMEY
QECGSPCVD-----TCSNPQHSQVCEDHCVAGCFCPE---G---------MVLDDSNQT-
---GCVPVSQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CACLYNGTLYAPGTSYSTDCTKCTCSGGQWSCQEVPCSGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVMGGSHIS
TFDERQYTVHGDCSYVLCKKPYDSNAFTVLAELRKCGLTESETCLKTVTLNLGGGKTV-I
TVKATGEVFVNQIY--TQLPVSTANATFFRPSTFFIIGQTNL-GLQLEIQLHP-IMQVSV
RIAPEFRGLTS-----GLCGNFNSMQADDFQTISGVVEGTAA-AFF------NTFKTQAA
CPNVKNIFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NEKYAQH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSQLT-DANGPFSQCHATVNPSTFFSNCMFDTCNCEKSEDCLCAALSSY
VRACAAKGVLLSDWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

E-GICEKPTIT

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSMTYQYHISTCQPTCRSLSE-EDVTCHVNFI
PVDGCTCPKGTFLDDSGKCVQATS

ENSGT00760000118896_5_Linker_15_17 (1525, 1586)

CPCYYKGSPVPNGESVHDNGAICTCTQGALTCIGGP
VL-TP---VCDAPMIYFDCRNATPG

PF01826 // ENSGT00760000118896_5_Domain_17 (1586, 1638)

DTGAG-CQKSCHTLD---MTC--YSSECVPGCVCP
NGLVADGNGSCVV-AEDCPCVHNEATYRPGETIQVGCNN-------C----TCENRMWQC
TDKPCLAT

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CAVYGDGHYITFDGQRYSFSGDCEYTLLQD--NCGGNGSSQDAFRVVTENIP
CGTTGTTCSKGIKIFLG-----------------------------------SYELKLSD
SKMEVVQKG-VGQEPPYFVHQMGNYLVVETDIGLVLLWDKKTSIFLRLSPEFKGKVCGLC
GNFDDNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVSDM-------LEFGNSWKLSPSCPDASVSKDPCTANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

QCSIINSATFSACHA--HVEPAKYYEACVNDACACDSGGDCECFCTAVAAYAQACH
EVGVCVSWR-TPDICPLFCDYYNPEGQCEWHYQPCGAP----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-----------

----MGAPSACRTLVLALAAMLVVPQAETQGPVEPSW----GNA----------------
---GHTMDGGAPTSSPTRRVSFVPPVTVFP--SLSPLNPAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 267)

CST-WGDFHYKTFDG
DVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-VVTRVVIKAQGLVLEASNGSVL
VNGQR---------EELPYSRTGLLVEQSGDYIKVSIRLVLTFL-DA-SLGLGSRGL---
----GHLDPKYANQTCGLCGDFNGLP

ENSGT00760000118896_5_Linker_0_4 (267, 339)

AFNEF---------YAHNARLTPLQFGNLQKLDG
PTEQCPDPLPLP-AGNCTDE-----------EGICHRT

PF08742 // ENSGT00760000118896_5_Domain_4 (339, 408)

LLGPAFAECHALVDSTAYLAAC
AQDLCRC------P----TCPCATFVEYSRQCAHAGGQPRNWRCPEL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CP--RT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPLNMQH
QECGSPCTD-----TCSNPQRAQLCEDHCVDGCFCPP---G---------TVLDDITHS-
---GCLPLGQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGAHIS
TYDEKLYDLHGDCSYVLS-KKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA-I
RVQADGGVFLNSIY--TQLPLSAANITLFTPSSFFIVVQTGL-GLQLLVQLVP-LMQVFV
RLDPAHQGQMC-----GLCGNFNQNQADDFTALSGVVEATGA-AFA------NTWKAQAA
CANARNSFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSLS
VE-NENYARH

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1456)

WCSRLT-DPNSAFSRCHSVINPKPFHSNCMFDTCNCEQSEDCLCAALSSY
VHACAAKGVQLSDWR

ENSGT00760000118896_5_Linker_14_15 (1456, 1467)

D-GVCTKYMQN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKSQRYAYVVDACQPTCRGLSE-ADVTCSVSFV
PVDGCTCPAGTFLNDAGACVPAQE

ENSGT00760000118896_5_Linker_15_17 (1525, 1570)

CPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGAS
LQKST---G

PF01826 // ENSGT00760000118896_5_Domain_17 (1570, 1638)

CAAPMVYLDCSNSSAGTPGAE-CLRSCHTLD---VGC--FSTHCVSGCVCP
PGLVSDGSGGCIA-EEDCPCVHNEATYKPGETIRVDCNT-------W----------WVV
SLSEAA------------------------------------------------------
------------------------------------------------------------
-------GG-EGGGVGE-----------------------------RQAEGLGGSLQGL-
--------------------------------------LP---SP-APPAPPASHPLT--
--S---------------------------------------------------------
-SGSSLLWG-PL-------------HRRHSSFHPCRSSH---------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------TGPP----EDS--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PGPFSL----S--------------------------------
-------SQGLHAAGSSRPP--P-ASRGLPS-----------------------------
------------------------------------------------------------
-RLPTP------------------------------------------------------
----------------RPWGSP--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------PPH------------------------------------
------------------------------------------------------------
--VHSGTQ--------------------G---EEAP-SKKGCPSP-SRPGRST-------
------------------------------------------------------------
---------------------------------------------RQCP---LGFR-QVF
RQGAPQ------------------------------------------------------
--------------------GCIXXXXXXXXXXXXX------------------------
------------------------------------------XXXX--------------
------------------------------------------------------------
----------------------------------------------------XX------
-------------------------------------XXXX-XX----------------
-XX----------------XXXXXX----------XTGTLPEQ-TTTPVATMSTIHPSST
PETTH-----------T-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------STVLT------------------------
------------------------------------------------------------
------------------------------------TT--ATTTRATSSTATPSSTP---
------------------------------------------------------------
------------------------------------------------------GTTWIL
TELTTAATTTAA------------------------------------------------
------------------------------------------------------------
------TGPTATPSSTPGTTWILT------------------------------EPSTTA
TATLTTGSTATASSTQATAGTPKV------------------------------LTTMAT
TPTVTS--SRATP---FSSPGT--------------------------------------
---------------------------------ATTLPAL-RSTATTPTAT---------
-------------SFTAIPS----------------------------------------
----------------------------SSLGTTWTR-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------LSQT------TTPTATMSTAT-------------------------
------------------------------------------------------PSSTPE
TAHTSTVLTAMATTTGA--------TGSVATP-YSTP-----------------------
---------GTAHT----------TKVPTT--TTTGFTATPSSSPGTAH-----------
------------------------------------------------------------
------TLPVRISTTSTP------------------------------------------
------------------------------------------------TTSGSTVTPSSI
PETTHTGTVLTTTTTTVGT-GS-----MATPSSST------------------QTSGTPP
SLITTVTTITAT--GSTTNPSST-PGTT---PIPPVLT-TTATTPAATSSTVTPSSALGT
THTPPVPNTTATTHGRS---------------------LSTSSPHTVPTAWTSATSGTLG
TTHITEPSTVTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATS--R
NTTTATPSKTRTSTLLPS--------SPTS------APITTVVTTGCEPQCA

PF13330 // ENSGT00760000118896_5_Domain_44 (5813, 5924)

WS------
EWLDYSYPMPGP-SGGDFDTYSNIRA-AGGAICEQPL---GLECR-AQAQPGVPLRELGQ
VVECS-----------LDFGLVCRNREQVGKFKMCFNYEIRVFCCNY-------------
-----GR-CPSTPATSS--MTI-----------PSSTPGTT-WIL---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------TELTT-TATTTASTGSTA-------------------
--------------------------------------TPSSTPGTTWILTEPTTT----
------------------------ATVTVPTGSMATTSSTPGTAGTPNMTTT-ATTPTV-
----TS------------------------------------------------------
-----------------------------A------------------------------
-------------------------------------------------LHA--------
---------------------DK------------------------------Q------
------------------------------------------------------------
----------------------------QA------------------------------
---------------------------------------TITA--TALHPSSSP----LD
-------TG----------P-------------SRTA------------------TSHTW
PHV-----------------------------H--IPSS---------------------
--L-------------------RRP-----------------------------------
-------------------------------PHSTAL-----------------------
-TTRQHDK----------------------------------------------------
------------------------------------------------------------
------GHQFHG-------------------------------HTL---LHSGD------
------------------------------------------------------------
--------------------------------------------------------DLDP
HRADHITGPTA-----TPSSTPGTTWILTEPTTTATVT-VPTGSTATTSSTRATAGTPNV
SS-TATTPTVTGSKATPSSSAGTATTLPALISTATTPTATSFTAIPSSSLGTTWT---HL
SQTTTPTATMSTATPSSTPGTVHTSTVLTAM-----------ATTTGATSSVATPSSTPG
TAH---TT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------KV-----------
----------------------LTTAATTTRATSST------------------------
---------------------------------ATVSSTPGTTW----------------
--------------------------------------------------ILTELTTAAT
TTAATGSTATPSSTPGTTWILTEPSTTATVT-----------------------------
-------------------VPTGSMATASSTQATAGTPNVT---------TTATTPTVTS
SKATPSSSPGTAT-TLPALRSTAT----TPTATSFTAI------PSSSLGTTWTRLS---
------------------------------------------------------------
-------------------QTTTPTATMSTATPSSTPETAHTSTVLTTMAPTTGATGSV-
-------ATPSSTPGTAHTTKVLTTT---------TTG----FTATPSSSPWTARTLPVW
FSTTNK-----------PITSGSTVTP------SSIPGTT------RTPTVLTTTTTT--
----------------TVATGS-----MATPS--------------------SSTQTPGT
PPPLTTTATTITATGSTTPLSSTPGTTPIPPVLTSTATTPTVTSSKATPSSSPRTATTLP
VLTSTATKSTATSFTPIPS---------------STLG-----------------TTGTL
PEQTTTPVATMSTIHPSSTPETTHTSTVVTTTATTTRATSSTATPSSTPGTTWILTELTT
AATTTAVTGPTATPSSTPWTTWILTEPTTTATMTVPTGSMATAS----------------
--------------------STLGTA-----HTPKVVTTTATMPTATASTVPSSSTLG--
----------------TTHTPA----------V-LPS-SLP-TFSVSTVSSS-VL---TT
LRP---TGFPSSHFS-TPCFCR--------------------------------------
------------------------------------------------------------
---------------------------------------------------------AFG
QFFSPGEVIYN------KTD--------RAGCHFYAVCNQHCDIDRFQ-GACPTSPPPVS
SA----------PL----------------------------------------------
------------------------------------------SSPSPAPGCDNAIPLRQV
NETWTLENCTVARCVGDN-RVVLLDPK--PVANVTCVNKHLPIKVSDPSQPCD-FHYECE
C-----------------I

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLY
LDNHYCVASATAA-AARCPRALSIHYKSMDIVLTV-TM-VHGKEEGLILFDQIPVSSGFS
KNGVLVSVPGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDC
LQRDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TTAASCKDMAKTWLVPD----SRKDGCWAPTGTPPTASPPAPV------------
--SSTP---TPAPCPPQ-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10054)

CD--LM-------LSQVFAECHNLVPPGPFFNACISDHCR
-G---RLKVPCQSLEAYAELCRARGVCSDWRGATGGLCDLT--CPPTKVY----KPCGPI
QPATCNSRNQSPQ--------L-----EGLAEGCFCPEDQILFNAHMGICV-QA-C----
-PCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCEAQGQPPPCNRPGFVTVTRP
RADNPCCPETVCVCNTTTCP-QSLPVCPPGQESICTHEEGDCCPTFRCRP--QL

PF00093 // ENSGT00760000118896_5_Domain_60 (10255, 10328)

CSYNGT
------FYGVGATFPGA-LPCHMCTCLSGD---TQDPTVQCQEDACNNTTCPQGFEYKRV
AGQCCGECVQTACLTPDG------QPVQLN----ETWVNSRVDNCTVYLCEVEGGVHLLT
PQ--PASCPDV--S-----SCRGSLRKTGCCYSCE-E--D----------SCQVRVNTTV
LWHQGCET--EVNITFCEGSCPG-ASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGS
AILHTYTHVDECGCTPFCVPAPMAPPHTRGFPAQ--------EATAV-------------
-----------

----MGSRSWNWALVWASVALFTVWPAESQSQVEELS----SEHP--------------E
LTGDGQKVYSAPTSSSTWHVTFIPPMTVFP--TMSPANLAHNGRV

PF00094 // ENSGT00760000118896_5_Domain_0 (106, 266)

CST-WGDFHYKTFDG
DMFHFPGLCNYVFSSHCGATYEDFNIQLRRGLEGSRP-VVTHVVLRAQGLVIELANGSVL
VDGQ----------VELPYSRAGLLMEKTGGYVKLSIRLVLTFL-WN-E----DSAL---
----LELDSKYTNQTCGLCGDFNGL

ENSGT00760000118896_5_Linker_0_4 (266, 335)

PGVNEF---------YAHNTRLTPVQFGNLQKLDG
PTEQCQDTLPSA-VSNCTDR-----------EDI

PF08742 // ENSGT00760000118896_5_Domain_4 (335, 408)

CRRILLGPAFAECIALVDVNMYLDAC
VQDLCRC------P----TCPCATFAEYSRQCAHAGGHPQNWRSPDL

ENSGT00760000118896_5_Linker_4_5 (408, 414)

CN--WT

PF01826 // ENSGT00760000118896_5_Domain_5 (414, 491)

CPFNMEH
QECSSPCVD-----TCSNPQRSQLCEDHCMDGCFCPPG------------TVLDDIRHL-
---GCLPLEQ

ENSGT00760000118896_5_Linker_5_7 (491, 531)

CHCTRGGHTYAPGESFNTSCSSCTCSGGLWQCQDLPCPGT

PF00094 // ENSGT00760000118896_5_Domain_7 (531, 695)

CSVQGGSHVF
TYDEKLYNVHGDCSYVLS-KKCADSGFTVLVDLRKCGLTDTENCLKAVTLNLNSGDMV-I
RIQANGAVFLNSIF--TQLPMSAANVTIFSPSSFFIVVQTGM-GLQLQVQLVP-VMQVFV
RLDPSYHGQMC-----GLCGNFNQNQADDFTALSGVVEGTGA-AFS------NTWKTQAS
CPNSKNTFEDP-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------CSYS
VE-TENYAQK

PF08742 // ENSGT00760000118896_5_Domain_14 (1391, 1458)

WCSMLT-ESSGVFSACHATVSPVPFYSNCMFDTCNCENSEDCMCAALSSY
VHACAAKGVLLSGWRD-

ENSGT00760000118896_5_Linker_14_15 (1458, 1467)

NVCFKYMNN

PF01826 // ENSGT00760000118896_5_Domain_15 (1467, 1525)

CPKTKSYSYAVSTCEPTCRSLSE-ADVTCGVSFV
PVDGCTCPEGTFLNDKGHCVRDEE

ENSGT00760000118896_5_Linker_15_17 (1525, 1570)

CPCFFHGTVVAAREFIMDNGVVCSCEKGKLTCLGAL
MQKNT---E

PF01826 // ENSGT00760000118896_5_Domain_17 (1570, 1638)

CQAPMVYLDCNNASVGDQGSE-CLRSCQTLD---VEC--FSTHCVSGCVCP
SGLVADGNGGCIA-EEDCPCVHNEATYRPGESIRVDCNN-------C----TCRNRRWEC
TNQPCMGA

PF00094 // ENSGT00760000118896_5_Domain_20 (1689, 1876)

CVGYGDGHFVTFDGERYIFEGSCEYTLAQD--YCRGNTSTDGTFRIITENVP
CGTTGTTCSKTIKIFVE-----------------------------------SYELILHE
GNFKVVERG-PSGDPPYKIRYMGIFLVIEIRSGIVVSWDRKTSVFVRLQQHYKGRVCGLC
GNFDDNAINDFTTRS

ENSGT00760000118896_5_Linker_20_26 (1876, 1925)

QSVVSDV-------LEFGNSWKFSPSCPDAPVPKDPCTANPYRKS
WAQK

PF08742 // ENSGT00760000118896_5_Domain_26 (1925, 1995)

KCSIINSATFAACHS--QVDSTKYYEACVHDVCACDSGGDCECFCTAVAAYAQACR
DVGVCLSWR-TPDICPLFCDYYNPHGECEWHYQPCGAPCLKTCRNPAGRCLVDLPGLE--
--GCYPQCPPSQP--FFNEDQMKCVA--QCGC---------YDDDGNY------HDI-GT
QVPTAENCQSCL--------CTP-DGLKCVHNLT----ACICTYEGHTYHYDDVVYNTTD
GLGACLVAICKDNGTIIRTTEECPAVL----STT-PFTFTNT--LAPHTT----------
------------------------------------------------------------
-----------------------------TGSA---------------------------
------------------------------------------------------------
--------PTASTVSTVCVR----------------------------------------
----------------------------------------------------------EV
CR

PF13330 // ENSGT00760000118896_5_Domain_28 (2523, 2615)

WSIWYDESHPEPGMTGGDFETFENLRQKGYQVCQSPA---AIECRAEKFPSMDLQKLG
QKVNCDPSWGLKCLNSEQSP--P-LCYNYELRVLCCDYVP--CSSTLTSGASTTH-----
----------------------------------------------------SRPEISRE
SSWPTQSTQTAS------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------SVSKS----------
-----------TPLWTTE------GKET----------------------SLDTIH----
-----------SSRQTVTFT------------------------SK--------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------R
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------K----------
--------ATS-------------------------------------------------
-----------------------------------------------------H------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LIGSTNS--AS------------------------------------------
-----------S--------L-VT------------------------------SSAT--
-------------

PF13330 // ENSGT00760000118896_5_Domain_40 (4634, 5539)

SVF--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------N----
---SQTGSTSRA--------------STVT------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------QIISS
PKGDF--GMCYNYMIRVL

ENSGT00760000118896_5_Linker_40_44 (5539, 5812)

CCSVSHCQGVTT------------------------TAGSPP
TP-QTATTASSRSITHTSWPVSSISTITSTTE--------------------SISSP---
GKT----------------T-VL--------TMASSTATTTPR-----------------
-----E-------------------------TQTSS----------WLSTGL--------
-----SP----------------------A------LTTTRTTSTGCKFQC

PF13330 // ENSGT00760000118896_5_Domain_44 (5812, 5924)

TWT------
DWLDSDKPQPGQ-FGGDIETYYHIRNKTGIQVCKKPV---DIECE-AILFPNMSFQQLGQ
EVVCN-----------VDFGLICRNSKQA-NNQTCFNYHIRVLCCEED------------
-----MS-CLSTTGALSTTFSP-------VTESPHTAA----PLLSTS-----------T
AAPGS-------------------------------------------------------
----------------------------------------------------------PS
TVSISTNKRPS----EEVVSIGT------------TGTTERLSVSSLST----------S
SASPT--------------------TFLQTSK--------------------------EQ
-----------HSGKPNTTSWTASSSTPSTAKLTTSTGIST-------------------
--------------------------------------GFSRTITTLWSSLAPST-----
-------------------------------PTTPTRSTEPNSTLMT----TKNPPTLIT
SHTSNTTS----------------------------------------------------
-----------------------------FSKTPPGSSYT-------------AT-----
T----------------------------------VTS---STRSTPH------------
------VSSVTESSSPGT--------------------VS--------------------
------------------------------------------------------------
-------------------------------S----------------------------
----------------------------------------------------------IH
---TTLTTMPKT-------LQ--------------------PST--PALTTKQTSSTGIW
TRILTG----------------TA--------------------------------GTTF
SKLPPT-------------------------------SLTTVIE---------EL--STS
TPRIQ-------TLP-------------------------ET------------------
------------------------------------------------------------
---------------------------------MTTASTSQGTTYCQPKC

PF13330 // ENSGT00760000118896_5_Domain_50 (7191, 7290)

TWTEWFDVDS
PTSGVIRGDIETYENIRASGKKMCQAP-E---KIECRAENYPAVSI---DKVGQVVSCSL
ETGLVCKNEDQTDDFKMCF---NYNIRVL

ENSGT00760000118896_5_Linker_50_53 (7290, 7955)

CCDDYSHCPST-TAVP-----QTST------
----------------------------------------------TNK-----PK----
----------------ASNEVPTMATS---------------------------------
-------------------------------------------------SSTRQR-----
-------HSIKATTPSKTS-----------------------------------------
----------------------------------------------DSPMTTVIRTGSIP
STH----------------------------------SV---------------------
---------S-------------SPVTSTT------------------------------
---------CQPQCQWTGWNTSATSTPT--------------------------------
-------------------------------STS-KE-----------------------
------------------------------------------------------------
-NQSSSLASTR----TTVISTPLSSSTGCKPQCT

PF13330 // ENSGT00760000118896_5_Domain_53 (7955, 8050)

WSDWLDHSSPIPG---SSGGEFETYA
NIRAAGIAICEKPM----DLECDVVDQPHVPQQGSNQVINCSVNFGLVCRNLDQPGPFSV
CLNYRIRVL

ENSGT00760000118896_5_Linker_53_54 (8050, 8718)

CCDDYSHCPTLP---------------------------------------
--------------------------------------------------WSIHTPLIP-
FTT---------------------------------------------------------
------------------------------------------------------------
-----------------------------TV-----------------------------
----------------------------ASS-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------TES--------------------------------------------------
-------------------------TFQTKHPFSSPVP---------STQASTW------
-----TTLTDSGCAPRC

PF13330 // ENSGT00760000118896_5_Domain_54 (8718, 8941)

TWTD-----WFDADFPN---------------------PGPR-
-------GGDFEVYAVLREVGFVFCEQP----KDIQCR----SEKEPDRPLETLEQ----
-------VVQ------CDVRFGLICKN------INQSGPL------QYCDN---------
------------------------------------------------------YHVRLL
CCDNTTHCTTPPMATPSTLPSTSTLLS----THT------------------------SP
ISNTM-------------------------------------------------------
----------------------------------------------------T-------
------------------------------------------------------SPPV--
----------------ATSSTVPHSSSLEPTPTSP-VLTTATSPGATGPTAAPSSTTET-
-----------------THTPE----------L-SPS-S-QVAFSMSTVSPL-GL---ST
VRS---TVFSSQSVSPSPCFCQA-F----GQL----------------------------
------------------------------------------------------------
------------------------------------------------------------
--FLPGDVIYN------KTD--------GAGCQFYATCNQNCELDRFQ-GACPSSSPPVP
ST----------HV----------------------------------------------
------------------------------------------PLSTPLPGCDNASPPRQV
NESWTLENCTVARCQGNN-QIILEEPE--PVDNVTCVNKHLPIKVWDQ-EPCH-FHFECE
C-----------------F

PF00094 // ENSGT00760000118896_5_Domain_56 (9740, 9906)

CSGWGQSHYLTFDGTSYTFLDNCTSVLMREIHPRHGNLSIL
AHSYYCGATT--N-ATFCPRALSVNYNSMEIVLTI-TTTGSGKKESLVIWDQMLISSGYT
KNGVTVSLSGTTTMSVNISTIGTSITFDGHIFQIWLPYRYFSNNTEGQCGTCTNSQTDDC
RRPDG

ENSGT00760000118896_5_Linker_56_57 (9906, 9981)

TIASNCQDMAKDWLVPR----NSNNSCLAQPSPPPSTTSQPPV------------
--SSTS---TSTPCPTA-PL

PF08742 // ENSGT00760000118896_5_Domain_57 (9981, 10055)

CE--LM-------LSQVFAECHRFIPPDTFFSSCVNDHCN
AN---VTDMLCQSLEAYATLCRARGVCINWRNATEGCHLIS--DPHSSAA----------
---PPHTRTLSVS--------T-----EMQAEGCFCPENQLLFNSRMDICV-QE-C----
-RKCHSPT-MGQPGEHWISNCQSCVCDPSAVSVQCEPVQCESQ-ELPQCTKPGFVTMTRP
KADNPCCSETVCVCNTTTCP-KSLSKCEPGHELIRIYEEGSCCPNSICRD----------
------------------VPCQTCTCFSVG---NQEPKVECREILCT-TFCPQGFKYTLV
PGQCCGECVQDACFTPEG------QTVQPH----ETWVNSHVDNCTVYLCKAENGIHVLT
PL--PMSCPDV--S-----NCRGTLRKIGCCYSCEKEDSS----------TCQVRVSTTI
LRHKGCETEMAVNVTFCEGSCSG-TSNCTQLGFRLGLVCRN---LKVSRETGSI------
------RSLCSPQMAPGCSQL---------------------------------------
-----------