ENSGT00760000118896_4 : Linker Region Query Results

-------------------------------------------------CSTWGGGHFST
FDKYQYDFTGTCNYIFATVCDE-SSPDFNVQFRRGLDKKIARIIIELGPSVIIVEKESIF
VRSVGAIKLPYANNGIQIAPYGRST-RLVAKLMEMELVVMWNNEDYLMV-----------
---------------------------------LTEKKYMGKTCGMCGNYDGYELNDFVS
E--GK---LLDAYKYAALQKMDDPSEICLSEEIPIPAIP HK------------KYAMICS
QLLNLVSPTCSV--PKDGFVIRCQLDMQDCSEPGQKNCTCSTLSEYSRQCAMSHQVVLNW
RTENFC S-------VG----K CSANQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGT
VLDDISKNRTCVHLSQ CPCTLNGETYAPGETMKAACR----TCKCTMGQWNCKDLPCPGR
CSLEGGSFVTTFDSRSYRFHGVCTYILMKSSSLPNNGTLMAVYEKSGYSHSETSLSAIIY
LSTKD--KIVISQNELLTDDDELKRLPYRSGDITIFRQSSMFIQIHTVFDLEVLVQTSPV
FQAYVKVGSQFKGRTL---GLCGNYNGDTTDDFMTSMD ITEGTASLFVDSWRA-GNCNPA
LERETDPCALSQLN KISAETHCSILTKKGTVFEKCHTVVNPIPFYK------RCVYQACN
YEETFPYICSALGSYARTCSSMGLILE----------NWRESM-DNCT------------
----IPCTGNQTFSYNTQACDRTCLSLSYRALECHPTDIPIEGCHCPKGTYLNHKNECVR
KSHCPC-YLEDRKYILPDQS-TMSGGITCYCVNGRLSCTGKPQNP-AESCRAPKKYISCS
DNLENKYGA---TCAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPAEDCPCEY
GGLAYGRGEQIQTECEIC----TCRKGKWKCVQKSK---------CSSTCNLYGEGHITT
FDGQRFVFDGNC---EYI-------LAMDGCSVNRPHSSFK----IITENVICGKSGVTC
SRSISIYLGNLTLVLRDETFSVSGE-NPLVRYSVKKNALHLMFDIIIPGKYNMTLIWNKH
MNFFIKISRE-TQETICGLCGNYNGNMKDDFETRSK YVASNELEFVNSWKENPLCGDVY-
-FVVDPCSKNPYR KAWAEKTCSIINSQVF------SACHNKVNRMPYYEACVRDSCGCDI
GGDCECMCDAIAVYAMACLDKGICIDWRTPEFCPVYCEYYNSHQNTGSGGALSYAY-NND
NCTWHYRPCNCPNQNY--------------------------------------------
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--------------------------------KYVNIEGCYNCSHDEYFDYETEKCMPCG
KPSMT-TTVTTPS-----------------------------------------------
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--ITTSTKRTTSSKPISTPTASPTTASTETEKVAVT------------------------
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-HKRP-TVPH--SVPQFITQ---KTTPVTLASSTSQTSV-S-------------------
-REASPASSPEVPL---T--------------KTSP-------------SPSSLPVTSTS
SVSSSS--------SALPSTR---------------------------------------
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MLGL--WLL-LLLPHGGALLSTGEWGQADPP---E--------ALEKGWCSLWGAGHFST
FDHHAYDFLGTCNYIFAASCKGASP-TFSIQLRRGADGNISRIIVELGSSVVTVNKTTVS
IKDIGVVSLPYTSQGLQITPYGQSV-QLVTKQVELELVVMWGPDAHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKTDNEFLS
E-DG T---LLEPYKYAALQKLDDPNEICTFEAIPRPPVLQW----------SAAQVGI CT
ELLTQVSPECDV--PKKPLVLSCQVDMATCAQPGQQNCSCATLSEYSRRCSMAHRPVSNW
RGPGL CS-------VG----Q CPANQVYQECGTACIRTCSNPQHSCSSPCTFGCFCPKGM
VLNDLSNNHTCVPVSQ CPCLLNGVAYSPGEVVRAACQ----SCQCTMGHWTCTGQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPNEGTLMAVYDKSGYSHSETSLVAIIY
LSGQD--KIVISEDEV-TNNGDTKWLPYQTRNITIFRQTSTHLQMATTFGLEIVVQRQPV
FQVYITLGPQFRGQTR---GLCGNFNGNTTDEFTSSA GIDEGTAALFVDSWRA-GNCPAA
LEREIDPCSMSQLNKMYAET HCSVLLKKDGVFEKCHAVLDPKPFYK------RCVYQACN
YEETFPHICAALGAYVHACSSQAVLLG----------DWRDSV-DNCT------------
----IP CTGNRTFSQQSQACDHTCLSLSNREVECHPSAVPVDGCNCPDGTYLDHRNECVR
KAQ CPC-LLESHKFILAGQS-TMVNGIICHCINGRLSCPGQSQVF-LAS CPAPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGITCVPTKCEPGCVCPEGFYEDTSGQCVLPGQ CPCDF
AGVSYPGGAVLRTDCKNC----TCSQGKWTCQQSAH---------CPST CTLYGEGHIIT
FDGQRFVFNGNC---KYT-------LATDDCGAN-SQPSFK----ILVENVVCGKSGATC
SRAIQILLGGLTITMADRNYSISGE-NSQVHVLVKPSSLNLVLDVDIPNRLNMTLVWNKH
MSVSIRVHRA-SQDALCGLCGNCNGNMKDDFETRS KYVASNELEFVNSWKESPLCSDAS-
-YAEDPCSLNPFRRPWAER KCSIIHSQTF------TACHSKVYRMPYYEACVRDACLCDK
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPIYCDFYNTHSQV-GDGKFQYTQ--EA
NCTWHYQPCLCPGRLD-SFPDTNV------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHRTGTCVPCS
KSSLCLPA-TDVGFQP--ST---GA---------SRTTSPGPSSLPIATYPTAQPSTP--
--------------------------------ASTEDWTLLTTRMPSALSSGAATSDLTA
TRRSTPTGLTVTEAITQATAAPESQGTKSTAQST-ARTTE------APPSSRPG------
------------TLPSP-------------------------------------------
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MLRGQQLL--LLLFFKGPLINAGAWTGDATD---SNTEDNLPSSPEKGWCSTWGAGHFST
FDHHEYDFKGMCNYVFTATCRDASP-TFSIQLRRDRDGNISRIIIELGASVVTVNKAIVS
VRDIGVVSLPYTSNGLQITPYGQSV-QLVAKQLELELVVIWGPDAHLM------------
--------------------------------VLVEKKYMGKLCGLCGNFDGKTDNEFLS
E-DG K---LLEPHKYATLQKLDDPNEICAHEAIPSPTTLE-----------T-RYAHICN
QLLTLVSP GCDV--PKEPLVLSCQADMAECAQPGRQNCSCATLSEYSRRCNVAGQPVRNW
RTPGL CP-------VS----Q CPANQVYQECGEVCVKTCSNPQHSCSSFCTFGCFCPHGT
LLDDISKNQSCVPVSQ CPCMLNGVVYGPGEITRTACQ----TCQCTMGRWTCTKQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPLLPNEGTLMAVYDKSGYSHSETSLVSIIY
LSKKD--KIVISEDEVVTNNGDTKLLPYKTHNITIFRQTSTHLQMVTTFGLELVVQLQPV
FQAHITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GIDEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHTVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSARGILLL----------GWRSSV-DNCT------------
----VP CTGNRTFSYDSKACDRTCLSLSDRETECHASAVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-MLDSYKFVQADQS-TMINGVICYCINGRLSCPRQAEMF-LAS CPEPKTLQSCS
QSSEDKFGA---ACAPTCQMLATGIDCVPTKCEPGCICPKGLYENSDGQCVPAEE CPCDF
AGVSYPGGSELHTDCKNC----TCSQGKWTCQLSAQ---------CPST CVLYGEGHVVT
FDGQRFVFEGNC---EYT-------LATDDCGANSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLSITMADRNYTVSGE-EPLVHLQVKPSPLNLVLDIGIPGRLNLTLVWNKH
MSVSIKISRA-TQDALCGLCGNSNGNMKDDFETRS KYVASSELEFVNSWKENPLCGDAS-
-YVVDPCSLNTFRRSWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPVYCDFYNIHTLV-GEKEYQYAQ--EA
NCTWHYQPCLCPGSLG-SFPDTNI------------------------------------
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-------------------------------------EGCYNCSHNEYFDHKEGTCVPCA
PPTTTLPP-ATTGSQPTTAT---PTSPEFYGSSSA-ATPVGPSYLPGLPTP---------
-----------------APSTPSSTE-------EVTDWTTPKKSTVS-SE----------
-----------------------------YPQTT-EAT---------APLTSPLP-----
----PTSTPRSTPTRLPVTQATTKPTASSP---SSSTKTTAQ-FTESTTVT--------P
PTSVMPEMSTSR----GESR----------------------------------PLGSQG
--------------TR--P-TAYICVPEQSCFSHWKFLT---------------VHPS--
VTLQSGLLLP-------------PLA----------------------------------
----GSLG----------------CL------GSSRILHR---VWSAV------------
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--MLGPWLL---LLFCGGTLLSGLDGTSFAHPELQRLKNSPQTXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX-XXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
X-X--X----XXXXXX----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------------XXXXXX
XXXXXXXXXXXX---XXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XSPGLCS-------LG----QCPANQVYQECGEACVKTCSNPQHSCSDFCTFGCFCPEGM
VLDDISKNLTCVPVAR CPCTLGGVTYAPGEITADTCR----TCRCTMGRWDCEERPCPRH
CALEGGSFVTTFDARPYRFHGACTYTLLQSPQLPDGGSLLAAYDKSGYSHSETSLVAVIY
VSSQD--KIVISQDEV-TNNGDTKRLPYKAGNITVFRQTSTHLQMATTFGLELVIRLRPV
FQAYITVGPHFRGQTK---GLCGNFNGDTTDDFTTSMG IAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLN KVSAETHCSVLVKTGTVFEKCHALVNPKPFYK------RCVYQACN
YEETFPHICAALGDYAHTCASRGVLLR----------GWRDSV-DNCT------------
----VPCTGNQTFSYDSHACGRTCLSLSDRTAECHPSAVPVDGCNCPEGTYLNHEAKCVH
KAQCPC-LLANHKFIPATQS-TMVDGVVCHCTNGRLNCPGRPQML-LAACSAPKTLRSCS
QSSGDEFGA---ACAPTCQMLATGTPCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---
-XXXXXXXXXXXXXXXXXXXXXTCSRGKWTCQQRAR---------CSSTCTLYGEGHVVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----IVTENVMCGKSGVTC
SRAIRISLGGLSITLADRNYTVSGA-DPHAHYRVQAGSLNLVLDVTIGSSYNLTLVWNKH
MSVSIKITRA-AQGTLCGLCGNDNGNMKDDFETRSM YVASSELEFVNSWKESPLCGDAS-
-LLLSPCTLNVLR HAWAMRKCNIINSQTF------AACHSQXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIYCGFYNTHTRA-NDGQFQYTQ--EA
NCTWHYQPCLCPQRLH-SFPNTNT------------------------------------
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-------------------------------------EGCYNCSQDEYFDHNEGTCVPCE
PTPPPATT-XXXXXXXXXXX--------X---XX-----------X-XXXX---------
------------------------------------XXXXXXX--XX-------------
---------------------------XXXXXXX-XXX---------XXXX-XX------
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-----------------XX-----------------------------------------
---XXXXXXXXXXXSPPKT-TAVTK-----------TTL---------------SSTATG
PTVTQATAQPTASSISTAKQPTG-------------------------------------
-------------------------WA-------------------TAHSTEA-------
--Q----------------------SPPATS--ET------------PTLPSATNDWTT-
------ET----------------------------------------------------
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----------------------------------------------SN------------
-GWETGTR-----------------SSGL-------------------------------
---------------------SLTTQ----------------------------------
----P-----E--GSAVQTKPATESRPHTPFATVSAP---------TGSV-----SITGP
PTGTS--------------FT-TTIVPSPSPPETTIST--HGPNVATSAVALTSHTITPT
ARSTS----SHSARPTGSHPPP-----------------------TT-------------
-------------SLSD-----------------------------------------TT
PLHTHTKPTSKETGTPVTH-----------------------------------------
-------------------------------------TTPATTSSPHTPFTTVSAPT---
--DSVSITAHTTGPPTGTSFSTT--IVPSPSRPETTLSTHGPNVATSAVTPTSLRMITPT
RYEVHTFSDST-TPTGTY-------------------------------SP---------
-STHV-------------------------------------------------------
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PVTTGTPETH-TAPATPSSPHTPLTTVS---APTGSVSIAAHSTGLPTGTSFSTT-IVPS
PSRPETTLSTHGPNVATSAV----------------------------------------
-----TLTSHHVITPTRHEAHTF-----------------------SDSTRP--------
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-------------------------------TGTYSPSTHVAVTGTSPSPTAPSGTKST-
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----------------------------------------------------------LS
-----PSLPAYSTH------------------------------ATTTTVYDKSTSEES-
---GTAVTHT-------AAATHSSPHTPFTTVSAPTGSVSIA--ATG---ATGTSSTTIV
PSPSRPETTLSTHGPNVATSAVTPTSHRVITPTRHEAHTSSD-----------------S
ARPTG--GP-RPPTPVPV-IGTS-PSPTSPPQTKTA------------TVST--EAPSSV
SSAVSSTLIVHPP-------SRLSPSPS--------------------------------
-----------PAEPEPRPGPLTT-----------------------SLFPITTSLSGSS
SGA-------LPRSPRLLSTPSSVQSFSPYSLFT-AAP-------MRPPTSS-----SV-
-------------------THTSSSLG--PQTLS-----PTASP----------------
-----SSLSS-----------------------------SAATSTVRWSPLPFTPP--S-
-----------------PFSPPTT------------------------------------
--PAPLLSPPSATASTQPL-HAVSQPTSSRSPSVTTGV--------LLPSLTSSTLGVTT
IPSSPAT-----------------------------------------------------
-----NLSTEHPRST----------------VLLTSSVTTPGSAPTPQ-----------G
APPSSLVTSP---------------------------------------ASSPGVCSVRE
LEEEITYQ----GCTANVTVTRCEGVCASSASFNVDTQQ-VDTHCGCCQPLGSHEKQVVL
ACPGPGAQGRR--LVLTLQVFSSCVCSTQRCGN---------------------------
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RAMLGP-LL-LLLSCGGALLGAGEWGGPQTP---SATP------DNRGRCSTWGAGHFST
FDGYTYDFSGTCNYVFAAVCKDAPS-TFSVQLRRGPGGNISRIIVELGASVVTVQDAVIT
VKDVGVVSLPHTSNGLQITPFGQSV-RLLAKQLEMELVVMWGPGAHLM------------
--------------------------------VLVERKYMGKMCGLCGNFDGEKTNEFLS
E-D GQ---LLEPHKYAALQKLDDPNEICAYEAIPSPRLLQ-----------A-EHAQACL
RLLTLVAPE CTV--PQEPFLLSCQADMAACAEPGRPNCSCATLSEYSRQCSVAGQPVSSW
RGPDL CS-------VG----Q CPANQVYRECGEACVRTCSNPRHSCSSFCTFGCFCPEGT
VLDDISKNHSCVPEPQ CPCMLSGVVYAPGEVTTAACQ----TCRCSGGHWECEERPCPRR
CALEGGSFVTTFDARPYRFHGTCTYVLVQSPQLPGGGSLMAAFDKSGYSHSETSLVAVIY
KSSQD--KIMISQDEVVTNNGDTKWLPYKTRNITVFRQTSTHLQMVTTFGLELVIQLWPV
FQLYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSM GITEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQPTARCWCRRAQWVG--AWAWKGLRGDSRGSSGRS------WCVYQACN
YEETFPHICAALGDYALACASRGVLLQ----------GWRNSV-DNCS------------
----IP CTGNQTFSYDSQACDHTCLSLTDREAECHPSAVPVDGCNCPEGTYLNHKSECVR
KAQCPC-LLDSHGFILADQS-TMVNGVVCRCVNGRLSCRAER--P-RAGCTQGGVWEECS
GGVSEGPRAVAAASGATLHGPLTLLPQVPTKCEPGCVCAKGLYENASGQCVPPEECPCEF
AGISYPRGAELHTDCKSC----TCSNGTWSCQQSAH---------CPSTCSLYGEGHVVT
FDGQRFVVNVGRGPRVWLLNT---PSPQDGCNASDSQPTFK----ILTENVVCAKSGATC
SRAIKILLGGLSIVLADANYTVSGE-DPGVHFRVKAGSLHLVLDVTIGSAYNLTLTWNKH
MAVFIKVARA-SQDPLCGLCGNYNGNMKDDFQTRS KYLASSELEFVNSWKESPLCGDTT-
-FALDPCSLNAFRRSWAER KCSIINSQTF------AACHGQVYRLPYYEACVQDTCACDT
GGDCECLCDAVAAYAKACVDKGVCVDWRSPDFCPVYCDFYNTHMQL-G-SEFQYTQ--QA
NCTWHYQPCLCPAWPQ-RVPD-NI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHDKGTCVPCS
KPIPLPTS--PHPSQSSRRA---PVPPAA---PWDTARHTGKRVSPCLPAP---------
-----------------NIHSPSLWSQGIPRPAEECGCRAGTSSGFSNRQLGGT------
---------------------------DHQLQRP-WGS---------IRPAPPVP-----
----ARPI------HADVGGGG---------------R-----MGSRGPDT--------S
AAAPTPGVPDSG----PGDT----------------------------------AKGFAG
------------------P-PWVGGGGAGGSAPDWPTSC---------------R-----
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--------------------------AAAHHAGSNR------------------------
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MLRVQQLLP-LLLLLRGSLINAGAWTGDATD---PNTEDSLQSSPEKSWCSTWGDGHFST
FDRHEYDFKGMCNYVFTATCGDALP-TFSIQLRRDRDGNISRIIVELGASVVTVNKAIIS
VRDIGVVSLPYTSNGLQITPYGQSV-RLVAKQLELELVVTWDSEAYLL------------
--------------------------------VLVEKKYMGKLCGLCGNFDGKADNEFLS
E-DG K---LLEPHKYATLQKLDDPNEICAHEAIPSPTTLK-----------T-RYAQICN
QLLTLVSP GCDV--PKEPLVLSCQADMADCAQPGQQNCSCATLSEYSRRCSMAGQAVRNW
RTPRL CP-------VS----Q CPANQVYQECGEVCVKTCSNPQHSCSNFCTFGCFCPHGT
LLDDISRNHSCVPVSQ CPCMLNGVVYGPGEITRTACQ----TCQCTMGRWTCTEQPCPGH
CSLEGGSFVTTFDARPYRFHGSCTYTLLQSPQLPNEGTLMAVYEKSGYSHSETSLVSVIY
MSTKD--KIVISEDEVITNNGDTKLLPYKTRNITIFRQTSTHLQMATTFGLELVVQLQPI
FQVYIAVGPQFKGKTR---GLCGNFNGDTTDEFTTSM GIDEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHTVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSSRGILLL----------GWRNSV-DNCT------------
----VP CTGNRTFSYDSKACDRTCLSLSDRETECHTSAVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDSNKFVQADQS-TMINGVICYCINGRLSCPRQAEMF-LAS CPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIACVPTKCEPGCTCPTGLYENSNGQCVPAEE CPCDF
AGMSYPGGSELHTDCKTC----TCSQGRWTCQLSTQ---------CPST CVLYGEGHIIT
FDGQRFVFDGNC---EYT-------LATDDCGANSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLSITMADRNYTVSGE-EPLVHLQVKPSPLNLILDIGIPGRLNLTLVWNKH
MSVSIKIRRA-TQDALCGLCGNSNGNMKDDFETRS KYVASDEMEFVNSWKESPLCGDAS-
-YVVDPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPVYCDFYNVHTLV-GENEYQYAQ--EA
NCTWHYQPCLCPGSLE-SFPDTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHKEGTCVPCG
KSSRPLP---PDSSQPTTAA---PTSTEVHSPSSA-STPLGPSDLPSLPTP---------
-----------------PPSAPSSTE-------EVTHWTTPKKSTVSSGE----------
-----------------------------HPQTT-VAT---------TPLTSPLA-----
----PTSIPKTTPTRLPVTQATSKPTASST---SPSTKTTAQ-FTESTTVA--------K
LTSEGPGMSTSE----GNQS----------------------------------QMFNSG
PQYRKIN------SERPTA---YIGVPEQSCYSYWKLLA---------------YYPS--
VTLQSGLLDLLS--------TYPSWS----------------------------------
----LQLA----------------GR------GATNYLPG---LCGKCDS----------
--NSLPGFLC--------LLC---------------------------------------
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-------------------------------------------------CSTWGGGHFST
FDKYQYDFTGTCNYIFATVCDE-SSPDFNIQFRRGLDKKIARIIIELGPSVIIVEKDSIS
VRSVGVIKLPYANNGIQIAPYGRSV-RLVAKLMEMELVVMWNNEDYLMV-----------
---------------------------------LTEKKYMGKTCGMCGNYDGYELNDFVS
E--GK---LLDTYKFAALQKMDDPSEICLSEEMSIPSIP HK------------KYAMICS
QLLNLVSPTCSV--PKDGFVTRCQLDMQDCSEPGQKNCTCSTLSEYSRQCAMSHQVVFNW
RTENFC S-------VG----K CSANQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGT
VLDDISKNRTCVHLEQ CPCTLNGETYAPGDTMKAACR----TCKCTMGQWNCKELPCPGR
CSLEGGSFVTTFDSRSYRFHGVCTYILMKSSSLPHNGTLMAIYEKSGYSHSETSLSAIIY
LSTKD--KIVISQNELLTDDDELKRLPYKSGDITIFKQSSMFIQMHTEFGLELIVQTSPV
FQAYVKVSSQFQGRTL---GLCGNYNGDTTDDFMTSMD ITEGTASLFVDSWRA-GNCLPA
MERETDPCALSQLN KISAETHCSILTKKGTVFEKCHAVVNPTPFYK------RCVYQACN
YEETFPYICSALGSYARTCSAMGF-------------NWRNSM-DNCT------------
----ITCTGNQTFSYNTQACERTCLSLSNPTLECHPTDIPIEGCHCPKGMYLNHKNECVR
KSYCPC-YLEDRKYILPDQS-TMTGGITCYCVNGRLSCTGKLQNP-AESCKAPKKYISCS
DSLENKYGA---ACAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPAEECPCEY
GGLSYRKGEQIQTECEIC----TCRKGKWKCVQKSR---------CSSTCNLYGEGHITT
FDGQRFVFDGNC---EYI-------LAMDGCNVNRPLSSFK----IVTENVICGKSGVTC
SRSISIYLGNLTIILRDETFSISGK-NLQVRYNVKKNALHLMFDIIIPGKYNMTLVWNKH
MNFFIKISRE-TQETICGLCGNYNGNMKDDFETRSK YVASNELEFVNSWKENPLCGDVY-
-FVVDPCSKNPYR KAWAEKTCSIINSQVF------SACHNKVNRMPYYEACVRDSCGCDI
GGDCECMCDAIAVYAMACLDKGICIDWRTPEFCPVYCEYYNYHRKTGSGDAYSYGS--SV
NCTWHYRPCNCPNQYY--------------------------------------------
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--------------------------------KYMNIEGCYNCSHDEYFDYEKEKCMPCA
ASKT--------------------------------------------------------
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------------TVPPLTTE---KTTPVTSFTSTSKTSV-S-------------------
-SEASPTSSPEIPL---T--------------TTSP-------------ALSSTLSTRLP
TPAPSTLFSITSPSTSMPKTTTTTLWPKLSSLITSAATESPTPASS------------TL
STAKTSLLPSSASSPFSS------------------------------------------
--------------VSSTVLS----TS-LPGMYSS-------------------------
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MLRVQQLL--LLLLFGGSLINAGAWTGDATD---SNTEDSLQSSPEKGWCSTWGDGHFST
FDHHQYDFKGMCNYVFTSTCGDALP-TFSIQLRRDGDGNISRIIIELGASVVTVNKAIIS
VRDIGVVSLPYTSNGLQITPYGRSV-RLVAKQLEMELVAIWDQDDHLL------------
--------------------------------VLVEKKYMGKLCGLCGNFDGKADNEFLS
E-DG K---LLEPHKYATLQKLDDPSEICAHEAIPSPTILK-----------T-RYAQICN
QLLTLVSPG CDV--PKEPLVLSCQADMADCAQPGQQNCSCATLSEYSRRCSMAGRPVRNW
RTPAL CP-------VS----Q CPANQVYRECGEVCGKTCSNPQHSCSSFCTFGCFCPHGT
LLDDISRNHSCVPVSQ CPCMLNGVVYGPGEITRTACQ----TCQCTMGRWTCTEQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPNEGTLMAVYEKSGYSHSETSLVSIIY
MSKKD--KIVISEDEMVTNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLELVVQLQPI
FQVYITVGPRFKGKTR---GLCGNFNGDTTDEFTTSM GIDEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHTVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSSRGTLLL----------GWRNSV-DNCT------------
----VP CTGNRTFSYDSKACDRTCLSLSDRETECHTSAVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDSNKFVQADQS-TMINGVICYCINGRLSCPRQAEMF-LAS CPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIACVPTKCEPGCTCPKGLYENSEGQCVPAEE CPCDF
AGMSYPGGSELHTDCKTC----TCSQGRWTCQLNEQ---------CPST CVLYGEGHIIT
FDGQRFVFDGNC---EYT-------LATDDCGSNSSQPTFK----VLTENVICGKSGVTC
SRAIKITLGGLSITMADRNYTVSGE-EALVHLQVKPSPLNLVLDIGIPGRLNLTLVWNKH
MSVSIKIRHA-TQDALCGLCGNSNGNMKDDFETRS KYVASNELEFVNSWKESPLCGDAS-
-YVVDPCSLNTFRRPWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPVYCDFYNIHTLV-GENQYQYAQ--EA
NCTWHYQPCLCPGSLG-SFLDTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHKEGTCVPCG
KSTHTRP---PTGSQPTTAT---PTSTEFSSSSSA-ATPVGPSYLPGLPTP---------
-----------------PASAPSSTE-------EVTDWTTPKKSTVSSGE----------
-----------------------------FPQTT-VAT---------TALTSPLP-----
----PTSIPKSTPSMLPVTQATTKPTVSSL---SPSTNTTAQ-FTESTTVT--------P
ITSERPGMSTSQ----GE------------------------------------------
------------------------------SRPMGKLHR---------------GESQ--
VG---TKVTCSW--------ASISRS----------------------------------
----LQLA----------------GR------GATDYLPR---LRGKCNS----------
--NSLPGFLC--------LLCQVSC-----------------------------------
------------------------------------------------------------
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MLGPRLLLL-LLLPCGALTRPAGRDTGPQDP---A-TVST---APDKGWCSTWGTSHFST
FDHQAYDFSGTCNYIFAAICKETPP-AFSVQLRRGLDGSISRIIVELGASAITVDNGTIS
VKDVGVVSLPYTSNGLRITPYGQSV-QLVAKQLELELVVLWGPDPHLMV-----------
---------------------------------LVERKYMGQMCGLCGDFDGNVDNDFMS
E-DG K---LLEPHKFAALQKLDDPNEICAYEVIPSSPTLR---------------AQTCA
QLLALVSP TCDV--PKEPLVHSCQADLATCRQPRQPNCSCATLSEFSRRCSLVGQPVSRW
RSP T----------LG----P CPASQEYQECGAACTRTCSNPWHSCPSSCTFGCFCPEGM
VLDDLSLNHTCVPLSQ CPCMLNGAVYSPGEVREAACQ----TCQCTTGRWTCTEKPCPGT
CSLEGGSFVTTFDTRPYRFHGTCTYILLQSPQLPDEGTLMAVYEKSGYSHSETSLTAVIY
LSRKD--KIMISEDEVITNHGDTKWLPYKTRNITIFRQTSTHLQMATAFGLQLVVQLHPV
FQVYITVGPQFQGQTK---GLCGNFNGDTTDDFMTSM GIDEGTATLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSELVRTSGPFEKCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGAYAQACASQGVPLA----------GWRSSV-DNCT------------
----VP CTGNRTFSYDSRACRRTCLSLSDPEAECHVSAIPVDGCNCPEGTYLDHKGECVR
KAQ CPC-LLESSKFLPADQS-TVINGGICYCVNGRLSCSGQPQMF-LAS CPAPKRFQSCD
QSAEDKFGA---ACAPTCQMLATGTACVPTKCEPGCVCANGLYENPSGECVPPEQ CPCDF
AGVSYPGGTELHTDCKTC----TCSQGRWACRQGAH---------CPST CVLYGEGHVVT
FDGQRFVFDGNC---EYT-------LATDDCGTNSSQPTFK----ILTENVICGKSGVTC
SRAIETVLGGLSIMMANGNYTVHGK-DPRVHFRVQPSALSLVLDADIPGKLNLTLIWNKH
MSVSIKIHHS-SQDALCGLCGNANGNMKDDFETR SRYVASSELEFVNSWKESPLCGDTR-
-AAVEPCSLNAFRRAWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDTCGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPIYCDFYNTHPHV-G-GQAQPTQ--ED
DCLWHYRPCLCPGSLQ-NFEGTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGMAC------------------
---PRQPG-LGP-----------PVAE----------------------------APDTQ
VLPKLLSCPEPATCTLP----SM--------E----DIGSEQE-----------------
----------------------DKRPVLLC----------------E-LRK-A-------
---------------------------------GAKISGDAGTSDM--------------
-------SWGI---------Q---------------------------------RESVPV
------------E-SPPAT-PAVTTPATLPLVPTVTV-----------------TSTATG
HTVTTATTQPTV------SSASPATT----------------------------------
-------STAQATARTTVTAQTMTRETTHGQG-----------------ETQ--------
------------------------------------------------------------
---------------------------------------------AVV------CL--ST
-------AQHSRVK-NKHRTNGT-------------------------------------
---------------------------------------------------------DKP
RAWGDTG----QS-PT---TH----------RPHS-S-----------------LD----
-------------------------------------PW-------------------RG
GVG-KV------------------------------------------------------
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-------------------------------

--MLRPWL---LLSCCGALLSTGLADTSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASIVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEAVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GM---FLALHKFAALQKLDDPGEICTSEDIPNTHHVSKGAPGGPHHRRPALTSPICT
QLLTLVAP ECSV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAALRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGACTYILLQSPQLPEDGALMAVYDKSGFSQSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACASRGVLLW----------GWRSSV-DNCT------------
----VP CTGNTTFSYNSQACERTCLSLSDRATECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIINGVTCYCINGRLSCPQRPQMF-LAT CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQGTH---------CPST CTLYGEGHIVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVR-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-GHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SIPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQPS----------TTGSRPTQVWPTTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSKHT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------ESPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----PGT----T--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-DQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPEQPT-------------R-
----PTA--TET-T--QTGMTTEYTTPQTPHITHSPP------------VG-SLVTSTGP
MTATS--------------FQTTTTYPTPSHPQTTLPT--HVPPFSTSSVTPTTHTVVIP
THAQMSTSASIHSTPTGTIPPQ--------TTVKSTRSTHTAPPMTATTSRTSQDT----
-------HS----SFSTAKTS----TSLHSHVSSTHHPE----------------ITPTS
TTTINYNPTSTETSTTVVH-----------------------------------------
-------------------------------------SPLTTSSGPPKPFTTHSPPT---
--GS--IPISSTGPVTT-TLKTTT-TYPTTSHPQTTLPTHIPPSSTSLVSPSTHTVITPT
HAQVSTTTFIHLSPTGTIPPLT-------------------------------TFR----
------------------------------------------------------------
----------------------TTGSTHKTPPRTVTISGTSQA-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------H----SSFSTAKTSTSLHSH----PFSTHQPE-ITP
-TSTTTITPK----------QTSTGTGTPVA-----------------------------
--------------------NITWATSSRLPTGFTT--------------------HSPP
TGSSH--IS---STGPLTATSFQT---------TTTYPTPSQPHT-TLPTHIPPFSTSSV
TPS-TH-----TVITPTHAQVSTSAYIHSTPTGTIPPPTTVKATGTVSTHTAPPMTATTS
RTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QTPSSFSTAKTSTS--------RHTHASSTLHTEVTPTFT--T-ITPNPTSRIT-
---GTPVAHT-------TSATSSEPSTPFTTHSPATGSN--PISSTGPMTATSFKTITTY
PTTSQPQTTLSTHVPPLSTSLVTPTTHTVITPTHTQMSTSSSIHSV--------------
--PIG--TI-PPPT---T-VKATGSTHTAPSMTVTT------------SGTS--QAHSSF
STTTASSSFISSSSWRPPNSSSRPPSPPSATTQLPHLSSATTPVSTTNQLSSSFSPTPSA
QS-----SVS---------------------SHVPSSHSSHQTS----------SSAGTS
SSV-----VSTPVHSTTLSSS------------------------------S-----HSS
FFT-------------------H-----------PTTASGSASPFFPSSPAAS-------
-TTIRASLPHTI-SSPFTPSAL-----------LPIS-------TLTVSPTPSSHQASS-
------------------------------------------------------------
S-AAF-PSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF--------VSLTSGVTG
IPSSPLT-----------------------------------------------------
-----NLTTRHPGPTSL-----------PTTQFLTSSLTAHGSAP-ASA-----------
-PVSSLGTPTPT---------S--------------------------PG----VCSVQE
QQEEITFK----GCTANVTVTRCEGTCISAASYNTITQQ-VDAHCGCCRPLHSYEQQVEL
PCPDPSAPGRQ--LVLTLQVFSRCECSSVACGA---------------------------
------------------------------------------------------------
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-------------------------------

--MVQRWL---LLSCCGALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEAIIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEVVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTFQDIPSTHVRQA----------QHARI--CT
QLLTLVAP ECSV--SKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRW
RSPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSNNHTCVPVTQ CPCVLHGAMYAPGEVTIAAC----QTCRCTLGRWVCTERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI
FQAYVTVGPQFRGQTR---GLCGNFNGDTTDDFTTSM GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACSLRGVLLW----------GWRSSV-DNCT------------
----IP CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVR
KAQ CPC-ILEGYKFILAEQS-TVINGITCHCINGRLSCPQRPQMF-LAS CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----SCSRGRWACQQGTH---------CPST CTLYGEGHVIT
FDGQRFVFDGNC---EYI-------LATDVCGVNDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRH
MTILIRIARA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELELVNSWKESPLCGDVS-
-FVTDPCSLNAFRRSWAER KCSVINSQTF------ATCHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-GHGEYQYTQ--EA
NCTWHYQPCLCPSQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PPTTPQPP-TTP---QLPTTGSRPTQVWPMTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSNHT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTMTL----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTRTTTEYTTPQTPHTTHSPP---------T--AG-SPVPSTGP
VTATS--------------FHATTTYPTPSHPETTLPT--HVPPFSTSLVTPSTHTVITP
THAQMATSASNHSAPTGTIPPP--------TTLKATGSTHTAPPITPTTSGTS-QA----
-------HS----SFSTNKTP----TSLHSHTSSTHHPE----------------VTPTS
TTTITPNPTSTRTRTPVAH-----------------------------------------
-------------------------------------TNSATSSRPPPPFTTHSPPT---
--GS--SPFSSTGPMTATSFKTTT-TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPT
HAQMATSASIHSMPTGTIPPPT-------------------------------TLK----
------------------------------------------------------------
----------------------ATGSTHTAPTMTLTTSGTSQA--LSSLNTAKTSTSLHS
HTSSTHHAEATSTS-------------------------------------TTNITPNPT
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------STGTPPMTVTTSGTSQSR----SSFSTAKTSTSLHSH----TSSTHHPE-VTS
-TSTTSITPN----------HTSTGTRTPVA-----------------------------
--------------------HTTSATSSRLPTPFTT--------------------HSPP
TGTTP--IS---STGPVTATSFQT---------TTTYPTPSHPHT-TLPTHVPSFSTSLV
TPS-TH-----TVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGS--THTAPPMTPTTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QSPSSFSTAKTSTS--------LPYHTSSTHHPEVTPTST--TNITPKHTSTGT-
---RTPVAHT-------TSASSSRLPTPFTTHSPPTGSS--PFSSTGPMTATSFQTTTTY
PTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHST--------------
--PTG--TV-PPPT---T-LKATGSTHTAPPMTVTT------------SGTS--QTHSSF
STATASSSFISSSSWLPQNSSSRPPSSP-ITTQLPHLSSATTPVSTTNQLSSSFSPSPS-
--------APST-----------V------SSYVPSSHSSPQTSSP---------SVGTS
SSF-----VSAPVHSTTLSSG------------------------------S-----HSS
L---------------------STH----PTT-----ASVSASPLFPSSPAAS-------
-TTIRATLPHTI-SSPFTLSAL-----------LPIS-------TVTVSPTPSSHLASS-
------------------------------------------------------------
T-IAF-PSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF--------VSLTSGVTG
IPT-----------------SPVTNLTT--------------------------------
---------RHPGPTLS-----------PTTRFLTSSLTAHGSTP-ASA-----------
-PVSSLGTPTPT---------S--------------------------PG----VCSVRE
QQEEITFK----GCMANVTVTRCEGACISAASFNIITQQ-VDARCSCCRPLHSYEQQLEL
PCPDPSTPGRR--LVLTLQVFSHCVCSSVACGD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------

MLGPRLLLL-L-LPFGVALLRGGEWGEASRS---A-TLSA---APDKGWCSTWGTGHFAT
FDHHAYDFSGTCNYVFAATCKDALP-AFSVQLRRGLDGAISRLIVELGASTVTVGNGAIS
IKDVGVVSLPYTSNGLQIAPYGPSV-RLVAKQLELELVVLWGPDPHLMV-----------
---------------------------------LVERKYMGQMCGLCGDFDGNVDNDFIS
E-DG K---LLEPHKFAALQKLDDPSEICAYEAGHPHPGPRT----------R--CAETCT
RLLALVSP ECDV--PKESLVHSCQVDMAACDLPGQPNCSCATLSEFSRRCSMAGQPVSRW
RGP T----------LG----P CPASQEYRECGEACTETCSHPQHSCPGSCTFGCFCPEGT
VLNDLSTNRTCVPLSQ CPCMLNGAIYSPGEVTAAACR----TCQCTTGRWRCMEKPCPGT
CSLEGGSFVTTFDTRPYRFHGTCTYILLQSPQLPDEGTLMAVYDKSGYSHSETSLTAVIY
LSRKD--KIVISEDEVLTNHGDTKRLPYKTRNITIFRQTSTHLQMATTFGLELMVQLQPI
FQAYITVGPQFRGQAR---GLCGNFNGDTTDDFMTSM GIDEGTATLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAES HCSELVRKGGAFEKCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGTYAQACATQGVPLW----------GWRNSV-DNCT------------
----IP CTGNRTFSSNSRACGRTCLSLSDREAECHASAVPVDGCNCPEGSYLDHKGECVR
KAQ CPC-LLEGPKFLLADQS-AKLNGVICYCTNGRLSCSGQPQMS-LAS CLAPKTFQSCD
QSAEDKFGA---ACAPTCQMLATGTACVPTKCEPGCVCAKGLFENPRGECVPAEQ CPCDF
AGVSYPGGAELHTDCKTC----TCSQGRWACQQGSH---------CPST CVLYGEGHVVT
FDGQRFVFDGNC---KYI-------LATDDCGTNSSQPNFK----VLTENVICGKSGATC
SRAIETVLGGLSITMADSSYTVHGE-DPHVHFQVQSSALSLVLDAHIPGRLNLTLIWNKH
MSVSIKIHRT-SQDALCGLCGNANGNMKDDFETR SRYVASSELEFVNSWKESPLCGDTR-
-ATVEPCSLNAFRRSWAER KCSIINGQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAQACLDKGVCVDWRAPDFCPIYCDFYNTHPHA-G-GQDQPTQ--EG
DCLWHYRPCLCPGSLQ-SFEGTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSKDKYFDHSTGTCMPCG
ESAPGQPG-PGA-----------RVGR----------------------------RPPAA
------------------------------------------------------------
-----------------------QRSPSCC----------------P-TRS-R-------
---------------------------------CLHSARGRPEAPT--------------
-------AWRR---------S---------------------------------RES-ST
------------E-SPPTT-TAVTTPATSPRVPTVTV-----------------MSTATG
YTVTTATTEPTA------SSPSPATT----------------------------------
-------STAQSTARTTVVPLTVSTARTLPVS-----------------HPPQTTEP--T
--S---------------------------------------------GT----SLT---
-------------------------------TTSPAG--PRTPQSRAL------CL--VG
-------QGASSYSSSGLHPAGL-------------------------------------
------------------------------------------------------TLPLIP
RAMQRAGAGAGDH-PP---GL----------HRQR-D-----------------PG----
-------------------------------------PL-------------------RG
CLR-LLLQ-----------------------------------------VS---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

MFRGQQLL--LLLFFRGSLINAGAWTGDATD---SNSEDSLQSSSEKGWCSTWGADHFST
FDHHEYEFRGMCNYIFTATCGDALP-TFSIQLRRDRDGNISRIIMELGASVVTVNKAIIS
VRDIGVVSLPYTSNGLQITPYGQSV-QLVAKQLELELVVMWGPDAHLM------------
--------------------------------VLVEKKYMGKLCGLCGNFDGKRDNEFLS
E-DDK---LLEPYKYAVLQKLDDPNEICVHEPIPRPTTLKT----------S-RYAQICN
QLLTLVSPG CDV--PKESLVLSCQADMAKCAQPGQQNCSCATLSEYSHRCSMAGQPVRNW
RTPGL CS-------VG----Q CPANQVYQECGEVCVKTCSNPQHSCSSFCNFGCFCPHGT
LLDDISRNHTCVPVSQ CPCMLNGVIYSPGEITRTACQ----TCQCTMGRWTCTEQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPLLPNNGTLLAVYDKSGYSHSETSLVSVIY
LSKKD--KIVISTDEVITNNGDTKVLPYKTHNITIFRQTSTHLQMATTFGLEVVVQLHPV
FQAYITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GLDEGTASLFVDSWRA-GNCLAA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHTVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACASRGVLLS----------GWRSSV-DNCT------------
----VP CTGNRTFSYNSKACDRTCLSLSDRETECHASAVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDSSKFVQADQS-TMINGVICYCINGRLSCPRQAEMF-LAT CAEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIDCVPTKCESGCICPKGLYENSNGQCVPAEE CPCDF
AGVSYPGGSELHTDCKTC----TCSQGRWTCQLSAQ---------CPST CVLYGEGHVIT
FDGQRFVFDGNC---EYT-------LATDDCGANSSQPTFK----VVTENVICGKSGVTC
SRAIKISLGGLSITMADRNYTVSGE-EPLVHLQVKPSPLNLVLDVDIPGRLNLTLVWNKH
MSVSIKIRRA-TRDALCGLCGNSNGNMKDDFETRS KYVASSELEFVNSWKENPLCGDAS-
-YVVDPCSLNTFRRSWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPVYCDFYNIHTLV-GENEYQYSQ--EA
NCTWHYQPCLCPGSLG-TFPDTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHTEGTCVPCA
PPATTLPP-ATTGSQPTTAT---PTSTEFHSSSSA-ATPMGPSNFPGLPTP---------
-----------------PPSAPSSTE-------EVTGWTTPKKSSVSSGE----------
-----------------------------YSPTT-VGT---------TPLTSGLP-----
----PTSIPKSTPTRLPVTQATTKPTASSS---SSSTETTAQ-FTESTTMT--------P
LISAKPGMSTSQ----ETTS----------------------------------SSLTHP
SRTTQQQ----STSLPPTT-VWKTSTMGQPCYYQWKLLA---------------FYPS--
VTLQTGLFDLS----------IPPTD----------------------------------
----LQLA----------------GR------GARDYLPR---LHSKCDS----------
--NSLPGFVC--------LLCQFQY-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

--MLWPWL---LLSCCGALLSTGLADTSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASIVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEAVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLELHKFAALQKLDDPGEICTSEDIPNTHVR------------QGQHAQICT
QLLTLVAP ECSV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAALRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGACTYILLQSPQLPEEGALMAVYDKSGFSQSETSLVAVVY
LSRQE--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMTTSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACASRGVLLW----------GWRSSV-DNCT------------
----VP CTGNTTFSYNSQACERTCLSLSDHATECHASAVPVDGCNCPSGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIINGVTCYCINGRLSCPQRPQMF-LAT CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQGTH---------CPST CTLYGEGHIVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGKYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQPI-HHSPDGMSVHPGSRPTQVWPTTGTS---TTIGLLSST-RPSP---------
------------------------------------------------------------
-----------------------------SSKHT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------ESPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----PGT----T--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-DQELPGTTATQTTGP--HP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGMTTEYTTPQTPHITHSPP------------VG-SLVTSTGP
TTATS--------------FQTTTTYPTPSHPQTTLPT--HVPPFSTSSVTPTTHTVIIP
THAQMSTSASIHSTPTGTIPPP--------TTVKATGSTHTAPPMTATTSGTS-QA----
-------HS----SFSTAKTS----TPLQSHTSSTHHPE----------------VTPTS
T-TITPNPTSTGTGTPVVH-----------------------------------------
-------------------------------------TTSATSSRLPTTFTTHSPPT---
--ES--SPVSSTGPTTATSFQTTT-TYPTPSHPQTTLPTHGPSFSTSLVTPTTHTVITPT
HAQMSTSSSIHSVPIGTIPPPT-------------------------------TVK----
------------------------------------------------------------
----------------------VTGSTHTAPPITATTSGTSQA-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------H----SLFSTAKTSTSLHSH----TSSTHHPQ-VTP
-TST-TITPN----------PTSTGTGTPVA-----------------------------
--------------------HTTLATSSRLPTPFTT--------------------HSPP
TESSP--VS---STGPITATSFQI---------TTTYPTPSHPQT-TLPTHVPPFSTSLV
TPT-TH-----TVITPTQTQMSTSASIHSMPTGTISPPTTVKATGS--THTAPPMTATTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QALSSFSTAKTSTS--------LHSHSSSTHHPQVTPTST--T-ITPNPTTTGT-
---GTPVAHT-------TLATSSRLPTTFTTHSPPTGSS--PVSSTGPTTATSFKITTSY
PTPSHPQTTLSTHVPPFSTSLVTPTTHIVITPILPEMSTFSSIPTM--------------
--PTG--TI-SPPT---T-VKATGSTHTAPSMTVTT------------SGTS--QAHSSF
STTTASSSFISSSSWWPPNSSSRPPSPPSATTQLPHFSSATTPVSTTNELSSSFSPTPSA
QS-----SVS---------------------SHVPSSHSSPQTS----------SSAGTS
SSV-----VSTPVHSTTLSSS------------------------------S-----HSL
FFT-------------------H-----------PTTASGSASPLFPSSPAAS-------
-TTIRASLPHTI-SSPFTPSAL-----------LPIS-------TLTVSPTPSSHQASS-
------------------------------------------------------------
S-AAF-PSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF--------VSLTSGVTG
IPSSPLT-----------------------------------------------------
-----NLTTRHPGPTSL-----------PTTQFLTSSLTAHGSAP-ASA-----------
-PVSSLRTPTPT---------S--------------------------PG----VCSVQE
QQEEITFK----GCTANVTVTRCEGTCISAASYNTITQQ-VDAHCGCCRPLHSYEQQVEL
PCPDPSAPGQQ--LVLTLQVFSRCECSSVACGA---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

MLGPQLLL---LLSCGGALLSAGLDDSSSVPPGLRRLKDSPQTXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXLPYTSNGLQITPFGQSV-RLVAKQLELELVVMWGLGAHLM------------
--------------------------------VLVEKKHMGKMCGLCGNFDGEKANEFLS
E-DG Q---LLEPPKYAALQKLDDPNEICASEAIPSPRVP QA------------ENAQTCI
QLLTLVSRECNV--PKEPFLLSCQADMATCAQPGQHHCSCATLSEYSRQCSMAGQPVNSW
RGPGLC S-------VG----Q CPANQVYRECGETCVQTCSNPRRSCSGFCTFGCFCPEGM
VLDDISKNHSCVPVPQ CPCMLSGVVFAPGEVTTAACQ----TCRCSGGRWECVEQPCPRR
CALEGGSFVTTFDARPYRFHGTCTYILLQSPQLPDGGSLMAVYDKSGYSHSETSLVAVIY
VSSQD--KIVISQDEVITNNGDTKRLPYETRNITVFRQTSTHLQMVTTFGLELVIQLWPL
FQVYITAGPQFRGQTR---GLCGNFNGDTTDDFTTSMG ITEGTASLFVDSWRA-GNCPAA
RERETDPCSMSQLN KVCAETHCAVLVKKGTVFERCHAAVDPKPFYK------RCVYQACN
YEETFPRICAALGDYALTCTSRGVLLP----------GWRSSV-DNCS------------
----TPCTGNQTFSYDSQACGRTCLSLSDREVECHPSAVPVDGCNCPEGTYLNHKAECVR
EAQCPC-LLDSSKFILADQS-TMVNGVICYCVNGRLSCPAQPQML-LATCSAPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGTPCVPTKCEPGCVCAKGLYENASGQCVPPEECPCEF
AGVSYPQGAELHTDCKSC----TCSRGTWACQQSAR--------C-PSTCTLYGEGHVVT
FDGQRFVFDGNC---EYILAT-------DGCGASDSQPTFK----ILTENVVCGKSGVTC
SRAIKIFLGGLSIVLADGNYTVSGE-DPGVHFRVKAGSLHLVLDATVSSTYNLTLIWNKH
MTIFIKIARA-SQDALCGLCGNYNGNMKDDFQTRSKYLASSELEFVNSWKESPLCGDTT-
-FTQDPCSLNAFRRSWAERKCSIINSQTXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
-XX-------XXXXXXX-XXXXXXXXXX---X--XXXXXXXXXXX--XXXXXXXXX--XX
XXXXXXX-------XX-XXXXXXXXX---------------X------X-----------
-----------------------------------------------XXXX---------
---------------------XXXXXXX---XXXXXXXXXXXXXXXXXXDHDKGMCLPCT
SSPTVPLP-TAGSHSTE-------------------------------TRPT---TAA--
-AS-------TTVTP---------------------------------------------
------------------------------------------------------------
------------------------------------------------STPALSSTRPSP
SSPATPEAPTRT------PSLPA-------------------------------TPTATA
TAPTAQTQPTVPSGDLPQTTSTVTTRATSAPTTTATR-----------------RPTATA
PTVTQATTQPTGSSH------DTA------------------------------------
-----TRSTARSTARTTAAPPTPATSGTSTVXXXX---XXXXXXXXXXXXXXXXXXXXXX
XXX----X----XXXXXXXX-X------XXXX--XXXXXXXXXX---X-XXXXXXXXXX-
------XXXXXX-XXXXXXXX---XXXX-XXXXXXXXXX------XXXXXXXX-------
--XXXXX-----------------------------------------------------
------------XXXXX---XXX-XX-XXXXXXXXX----------XXXXXXX--XXX--
--XXXX--XX-X---XXXXXXX--------------XXXXXXX--X--------XX----
---------XX----XX----------------------XXXX------X--XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXX-XXXXXXXX
XXXXX--------------XXXXXXXX--XXXXXXXXX--XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXX-------XXXXXXXXXXXXXXXXXXXXXXXX-------
------XXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXX-----------XXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX------------------
-XX-----XXXXXXX--XXXXXXXXXXXXX---X-XXXXXXXXXXXXXXXXXXXXXX---
------XXXXXXX-XXXXXXXXXX-XXX------------X---XXXXXXXXXXXXXXXX
XXXXXXXXXXXXX----XXXXXXXXXXXXXXTPTA---TTLTKTTTGTTTP---------
-RT-SPLTKTTTGTSTQNPATDKTTTGTTTHNPATTKTTTETAAPTAALTKTTTGSTHHP
ATETT-------------------------------------------TGTATQTPPLTK
NTHHTHAPPLTTTT-------------------------------------TGTITPTAP
------PLIK-----------------------TTTGTSTHTTTG-----------TTPP
PSLTKTTRGTT---------TPTAPPLTKTTT------------GTTRAQNSVSTVLPQS
S-----------------SFS-------------STLSS-------ISKPSQ----SPFT
TSVSVSNLPHYP-----------SS------SSSTSTLSSLPSH----VSSHTTPPFISY
SPSPSAVST---------------SQSIPTA-----------------------------
--------------------SSAP--HSPS---------PSAPVTISHTAPLSASRFS--
----PATIVSVRLPLTPSSPTLSPLPTPSTMVLSTSQTTPSKPTSSALSSRSTTSKSTSL
TTR-----------------APTQ-----------------------------GLLSSTL
GVTAIPSSPATNLTTRQ-------PSTTGLPASVFLTG--------SITAHGSSSFPTP-
---VSSLVTSLPSSPXXXXXXXXX--------XXXX---------XXXXXXXXXXXXXXX
XXXXXXXFNTDTMQVDTKC----SCCHPLGS---------HEKQLVLPCPDPRVRGRRLT
LTLQVFSSCTCRSQRCGD------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------

--MLRPWL---LLSCCGTLLSTGLAATSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVIGLPYTSNGLQITPFGQSV-RLVAKQLELELEVMWGPDSHLMV-----------
---------------------------------RREGP---------------GADPCPA
P-PGK---FLEPHKFAALQKLDDPGEICTSEDIPNTHVRQA----------Q--HAQICT
QLLTLVAPECNV--SKEPFMLSCQADVAAATQPGPQNSSCATLSEYSRQCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAALRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGTFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-DNCRGVLGPQAVEPKL
VLPAVP CTGNTTFSYNSQACGRTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILADQS-TIINGVTCYCINGRLTCPQRLQMFL-AS CQAPKTFKSCN
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTCT---C-SRGRWDCQQGTH---------CPST CTLYGEGHVVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDMS-
-FVADPCSLNAFRSSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQPS----------TTGSRPTQVWPTTGTS---TTIGLLSST-GPSS---------
------------------------------------------------------------
-----------------------------SSKST-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------SSTATK
PTVTQATTRAT------ASTSSPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PPPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGP--RP---------------------------
----------------------------TPESTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGMTTEYTTPQTPHITHSPP------------VG-SPIASTGP
VTATS--------------FQTTTANSTPSHPHTTLPT--HVPPFSTSSVTLNTHTV-IP
THAQMSTSASIHSMPTGTIPPQ--------TTVKSTRSTHTAPPMTATTSRTS-QD----
-------NS----SFSTAKTS----TSLHSHASSTHHPE----------------VTPTS
TTNITPKSTSTGTGTPVTH-----------------------------------------
-------------------------------------TTSATSSRTPTPITTHSPPI---
--GS--TSVSSTGPMTATSFQTTT-TYPSPSHPQTTLPTHFPAFSTSLVTPSTHTVITPT
HAQRSTSSSIHSVPIGTIPPPT-------------------------------TVK----
------------------------------------------------------------
----------------------VTGSTHTAPPTTVTTSRTSQAHS--SFSTTTASTSLHS
HASSTHHPEITLTS-------------------------------------TTTITPNPT
STGTGTPVAHTTL-VTSSRPPPPFTTYS---LPTGS--SPVSSTGPITATSFQTTTTYPT
PSHPQTTLPTHVPPFSTSLV----------------------------------------
-----TPATHTVITPTHVHLSTS----------------------ASIHSTPTGTIPPST
ALTTTGSMHTAPSMMVTTSGTSKAP----SSFSTAKTSTSFYSH----ASSTHHPE-ITS
-TSTTNITPK----------STSARTSTPPHTPFTTHSPHSGSSPMTTTSF--------K
TT-TTYPTPSHPQTTLHTHVPPFSTTSSRLPPPVTT--------------------HFPP
TGSSP--LF---STGPMTPTSFKT---------TTTYPTPSHPQT-TLPTHVPPFSTSLV
TPS-TH-------------TMSTSASIHSMSTGTIVPPTTVSATGS--THTAPSMTGT--
---TTHSSFSTATTSTSLYSHASSTHHPEITPTSTTTNNPKSTSTGTGT--PVTRTSSTT
------------------------------------------------------------
----------------------------TT------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--YPT-PSHPQ-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

--MLRPWL---LLSCCGTLLSTGLAATSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDVGVIGLPYTSNGLQITPFGQSV-RLVAKQLELELEVMWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTSEDIPNTHVRQV----------QHVNHPGPP
QLLTLVAPE CNV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRQCSMLGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACMKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAAC----QTCQCTQGRWACRERPCPGH
CSLEGGSFITTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVIY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGTFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACSARGVPLW----------GWRSSV-DNCRGVLGPQAVEPKL
VLPAVP CTGNTTFSYNSQACERTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIINGWDCEGSPASSECPDCVPLFPAAS CQAPKTFKSCN
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWDCQQGTH---------CPST CTLYGEGHIVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADGNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNTFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPE-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQ----------PSTTGSRPTQVWPTTGTS---TTIGLLSST-GPSS---------
------------------------------------------------------------
-----------------------------SSKRT-SA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------SSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PPPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGP--RP---------------------------
----------------------------TPESTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGMTTEHTTPQTPHITHSPP------------VG-SPIASTGP
MTATS--------------FQTTTTYPTPSHPQTTLPT--HVPPFSTSLVTPSTHTVITT
THAQRSTSSSIHSVPIGTIPPP--------TTVKVTGSTHTAPPTTVTTSRTS-QA----
-------HS----SFSTTTAS----TSLHSHASSTHHPE----------------ITLTS
TTTITPNPTSTGTGTPVAY-----------------------------------------
-------------------------------------TTLVTSSRPPPPFTTYSPLT---
--GS--TPVSSTGPMTATSFQTTT-TYPTPSHPQTTLPTHVPPFSTSLVTPTTHTVITPT
HIHLSTSASIHSMPTGTIPPPT-------------------------------ALT----
------------------------------------------------------------
----------------------TTGSMHTAPSMTVTTSGTSKA--PSSFSTAKTSTSFYS
HASSTHHPEITSTS-------------------------------------TTTITPKST
SAGT--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MTTSVTSQAH----SSFSTTKTSTSLHSH----TSSTHQPE-ITP
-TSTTTITPN----------PTSTGTGTPVA-----------------------------
--------------------HTTLATSSRLPTIFTT--------------------HSPP
TGSTP--VS---STGRMTATSFQT---------TTTYPTPSHPQT-TLPTHVPPFSTSLV
TPT-TH-----TVITPTQTQMSTSASIYSMPTGTISPLTTVEATGS--THTAPPMTATTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QALSSFSTAKTSTS--------LHSHSSSTHHPEVTPTST--T-ITPNPTTTGT-
---GTPVAHT-------TSATSSRLPTPFTTHSPPTGST--PVSSTGPMTVTSFQSTTTY
PTPSHPQTTLPTHVPPFSTSLVTPTTHIVITPTHPQMSTFSSIPSM--------------
--PTG--TI-SPST---M-VKATGSTHTAPPMIVTT------------SGTR--QTHSSF
STTTA-SSFLSSSSWRPQNSSSRPPSPPSATTQLPNLSSATTPVSTTNQLSSSFSPTPSA
QS-----SVS---------------------SHVPSSHSSPQTS----------SSAGTS
SSV-----VSTPVHSTTLSSS------------------------------S-----HSF
FTH--------------------------P-----MTASGSASPLFPSSPAAS-------
-TTIRASLPHTI-SSPFTLSAL-----------LPIS-------TLTVSPTPSSHPASS-
------------------------------------------------------------
T-TAF-LSTPRTTASTHAAPAFSSQSTTSRSTSLTTRVPTSGF--------VSLTWGVTG
IPSSPV-----------------T------------------------------------
-----NITTRHPGPTSL-----------PTTQFLTSSLTAHGSAP-ASA-----------
-PVSSLGTPTPT---------S--------------------------PG----VCSVQE
RQEEITFK----GCMANVTVTRCEGTCISAASFNTITQQ-MDAHCGCCRPLHSHEQQLEL
PCPDPSAPGRW--LILTLQVFSRCECSSVACGD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

MLGPRLLLL--LLPFGAALLRGGEWGACQGK---G-ARAARLTASLGGWA----------
----------------------AYQ-PGGVQLRRGLDGAISRLIVELGASTVTVGNGAIS
IKDVGVVSLPYTSNGLQIAPYGPSV-RLVAKQLELELVVLWGPDPHLMVRMQGTQ----Q
TWSLEQA-QGGWGAAP--------SSACHPLQVLVERKYMGQMCGLCGDFDGNVDNDFIS
E-DG K---LLEPHKFAALQKLDDPSEICAYEAGHPHPGPRT----------R--CAETCT
RLLALVSP ECDV--PKESLVHSCQVDMAACDLPGQPNCSCATLSEFSRRCSMAGQPVSRW
RGP T----------LG----P CPASQEYRECGEACTETCSHPQHSCPGSCTFGCFCPEGT
VLNDLSTNRTCVPLSQ CPCMLNGAIYSPGEVTAAACR----TCQCTTGRWRGMEKPCPGT
CSLEGGSFVTTFDTRPYRFHGTCTYILLQSPQLPDEGTLMAVYDKSGYSHSETSLTAVIY
LSRKD--KIVISEDEVLTNHGDTKRLPYKTRNITIFRQTSTHLQMATTFGLELMVQLQPI
FQAYITVGPQFRGQAR---GLCGNFNGDTTDDFMTSM GIDEGTATLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAES HCSELVRKGGAFEKCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGTYAQACATQGVPLW----------GWRNSV-DNCT------------
----IP CTGNRTFSSNSRACGRTCLSLSDREVECHASAVPVDGCNCPEGSYLDHKGECVR
KAQ CPC-LLEGPKFLLADQS-AKLNGVIWCG---H---LTHPPAP-TAS CLAPKTFQSCD
QSAEDKFGA---ACAPTCQMLATGTACVPTKCEPGCVCAKGLFENPRGECVPAEQ CPCDF
AGVSYPGGAELHTDCKTC----TCSQGRWACQQGSH---------CPST CVLYGEGHVVT
FDGQRFVFDGNC---KYI-------LATDDCGTNGSQPNFK----VLTENVICGKSGATC
SRAIETVLGGLSITMADSSYTVHGE-DPHVHFQVQSSALSLVLDAHIPGRLNLTLIWNKH
MSVSIKIHRT-SQDALCGLCGNANGNMKDDFETR SRYVASSELEFVNSWKESPLCGDTR-
-ATVEPCSLNAFRRSWAER KCSIINGQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAQACLDKGVCVDWRAPDFCPIYCDFYNTHPHA-G-GQDQPTQ--EG
DCLWHYRPCLCPGSLQ-SFEGTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSKDKYFDHSTGTCMPCG
ESAPGQPG-PGA-----------RVGR----------------------------RPPAA
HSPSRNLAG--VHCTLQ----SSLL-PTPPCQGCQAGWKGDRR-----------------
----------------------DGEGPLLNT----SPLAA------PPPTSPPL------
---------------------------------PPTSGDHPHTKPP--------------
-------GWAS---------L---------------------------------KGLFPA
------------E-SPPTT-TAVTTPATSPRVPTVTV-----------------MSTATG
YTVTTATTEPTA------SSPSPATT----------------------------------
-------STAQSTARTTVVPLTVSTWTRNPGQ-----------------GEQGPMGH--L
ESQ---------------------------------------------GKDGPTSIW---
-----------------------------GHGGQPGT--THTPNPGAP------CR--KP
-------VP-------------Q-------------------------------------
------------------------------------------------------TAHPGL
HKWGGRGTSSSDT-QEKMPGT----------GPTT-E--------------QYTLGE---
----------------------------TALATQHTRES-------------------RG
TATASTMQH-------TEITSSTL---QTHSPSHSAR---------TLPVS-HPPQTTEP
TSGTS--------------LTTTSTFPTTSEPQTLPPS--VSPTLTTTSVAPTSPSTPTS
---------------------------PTHPATVVTGTTHSPP-----------------
-------PL----TMTTTRTS----PVHMTQPSSTPHHE----------------STSSV
SAIITSSPTSTETSTTVAH-----------------------------------------
-------------------------------------PTSAIPTSAHTPFSTHSVPT---
--LSGAHSTLTTVPTSGTSLTTTS-TFPTTSEPQTLPPSVSPTLTTTSVAPTSPS--TPA
SPHTVSSAS--TMRPTSPTHPA-------------------------------TVV----
------------------------------------------------------------
-----------------------TGTTHSPPPLTMTTSATTQT--PMSLSTARTSPVHMT
QPSSTPHHESTSSVSAIITSSPT----------------------------ST-------
--ETSTTVAHPTS-AIPTSAHTPFSTHS---VPTLSGAHSTLTTVPTSGTSLTTTSTFPT
TSEPQTLPPSVSPTLTTTSV----------------------------------------
-----APTSPSTP-ASPH-TVS-----------------------SASTMRPTSPTHPAT
VV--TGTTHSPPPLTMTTSATTQTP----MSLSTARTSPVHMTQ----PSSTPHHE-STS
-SVSAIITSS----------PTSTETSTTVA-----------------------------
--------------------HPTSAIPTSAHTPFST--------------------HSVP
TLSGAHSTL---TTVPTSGTSLTT---------TSTFPTTSEPQT-LPPSVSPTLTTTSV
APT-SP-----S--TPASPHTVSSAS---TMRPTS---PTHPA-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------TVVTGTTHSPPPLTMT-----TS
--ATTQTPMSLSTARTSPV--------HMTQPSSTPHHESTSSVSAIITSSPT--STET-
---STTVAHP-------TSAIPTSAHTPFSTHSVPTLSGAHSTLTTVPTSGTSLTTTSTF
PTTSEPQTLPPSVSPTLTTTSVAPTS--PSTPASPHTVT-----------------SAST
MRPTS--TT-HPA----T-SGPQPPPSESPPVTSAWVSPTSQRP--STPTSP--PTFSSV
SPTNRLPAAMVTSTSSSHSAPGLSTVPV-ATS------------------------HMHT
SSPFSSLSSSGLLRSSVSPFPPSP----ASPVSPYPGL--STTSLSPANLPYSSAFPRET
SSS-------SPAPPSSTSSSPF-L----------SSP-------SRPPSPS-----PGT
TPQAPLTPSTAHPAPVPTGSTTSSL----PVPLS-----PLPSPLPPSIL----------
-PSVTLPVLSPLSPSPA--STL-----------TTGGSSCRPCTQLPTSTFPSSPA-ASP
T----------------------------------------TSP-PTLEVLST-------
--LSP-WVSSPVTSPTSSAGKWCPSSSGQHCTISPQGSLTPLVPYALFCPLLSPARADRC
LPHPASA-----------------------------------------------------
---PLGGRE-----SSM-----------PSA-PLGMRTSSPGPSSGPAGPRTPQSRALCL
VGQGASSYSSSG---------L--------------------------HP----PCSVRE
REQEITHQ----GCTANVTLAHCEGACASSSSFNVTTQQ-LDVHCACCKPLSSYTQEVPL
PCRDPSMPSRL--LMLTVRVAHSCVCGHQHCGD---------------------------
------------------------------------------------------------
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-----------------------------GGTQGSKTLPTISTAPDKGWCSTWGAGHFST
FDGHVYDFLGTCNYVFAATCEDMSP-TFSVQLRRGPSGNISRIIVELGTSAVTVQKAVIS
VKDVGVVSLPYSSTGLQITPFGRSV-QLVAKQLELELVVMWGPGSHLL------------
--------------------------------VLVEKRHMGKLCGLCGDFNGKRTDEFLS
E-EGK---PLEPHTYAALQRLDDPNEICTSTPVPRPQAPQA------------EHVRQAA
GAPERLSPGEG------------------------RPCSRAEMGGPGRRLGTVA-RGREA
QGPGLVG-------E-------------------------------HRATGPGNLCPTGM
VLDDVSKNHTCVPVAQCPCMLHGMAHAPGEVVTDACR----TCRCSLGHWVCTERPCPGR
CSLEGSSFVTTFDARPYRFHGACTYILLQSPQLPDGGSLVASYDKSGYSHSETALAAVIY
MSGED--KIVISRDEVLTNSGNTKWLPYKTRNITVFRQTSTHLQMTTTFGLELVVQLEPV
FQAYVTVGPQFRGQTR---GLCGTFNGDTTDDFMTST GIVEGTAPLFVDSWRT-GNCPAS
LEREIDPCSMSQLNKVC AETHCSVLVRDGTVFQSCHATVNPRPFYK------RCVYQACN
YEETLPHVCAALSDYARACATHGRLLR----------GWRDSV--N CT------------
----TP CTGNQTFGDNIRACGRTCLSLSDHTAECHPSAVPMDGCACPEGTYLNHKAQCVR
KAQ CPC-LLDGSKLIPADES-TMVNGAICYCVNGRLSCPGRPQLL-LAT CSAPKTFQSCD
ESSERTFGA---ACAPTCQRLATGTPCVPTKCEPGCVCAQGLYENATGHCVP LGRAPQPP
EP------HVPASGCPQI----TRPQGRQPCLLGLD--------SCAKKPHPQPLVHFPP
FSGTFC--QPQC---L------------EDRPPAESRPGQAWPTRSLTDGVP--LPQRTC
AGDAKPGGQGVSVVLADRNCTVHGE-DPHVRLQVATSPLNLV LDVVVGSSYNLTLIWNKR
MTVSISVTRG-SQGALCGLCGNYNGNMKDDFETRS NYVASSELEFVNSWKDSPLCGDAG-
-LALDPCSLNAFRR SWATRKCGIINSPTF------AACHSQVYHLPYYEACVRDACGCDT
SGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPVYCDFYNTHAP--GDGGYQYDQ--EA
DCTWHYQPCLCPGYPQ-SVPDTNTEGTG------------QA------------------
------------------------------------------------------------
-------------------------------------------------------GSPCA
QPHTSPQT-E-RAMS----------------SLV--------------PQSP---RAS--
-SPREPLGA---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----HPVPPSRT------PSS--------------------------------------S
PETIGEQAIYSITNESPRTIPAITLRPTSEPAPTVTL-----------------KSTATG
PMVTGATTKSTASTL------SSV------------------------------------
-----TRSTAQSTEHST-------------------------------------------
------------------------------------------------------------
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-------------------------------

MLRVRQLL--LLLLFRGPLIDAGAWTGDVTD---SDTEDNLQSSPEKGWCSTWGAGHFST
FDGHEYNFQGMCNYIFTATCGDDVPATFSIQLRRDMEGNISRIIMELGASVVTVNKETIS
VRDIGVVSLPYTSNGLQITPYGQSV-QLVAKQLELELVITWG PDAHLTEGQGGDEVGTPG
TLKQESKGSPAWAGSSLCIPT---ETN STTPQVQVETKYMGKLCGLCGNFDGKIDNEFLS
E-DG K---LLEAHKYATLQKLDDPNEICAHEAIPSTIILK-----------T-RYAQICN
QLLTLVSPG CDV--PKETLMLSCQADMAACARPGQPNCSCATLSEYSRRCSMTGQPVRNW
RTPAL CP-------MS----Q CPANQVYQECGEVCIKTCSNPQHSCSSPCTFGCFCPHGT
LLDDISGNQSCVPVNQ CPCMLNGMVYGPGEITKTACQ----TCQCTMGRWTCTKQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPNEGTLMAVYDKSGYSHSETSLVAIMY
LSKKD--KIVISEDEVITNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLELVFQMQPV
FQVYITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GIDEGTASLFVDSWRA-GNCPAA
LEREMDPCSMSQLNKVCAET HCSMLLKKGSVFEKCHSVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSARGILLW----------GWRNSV-DNCT------------
----VPCTGNRTFSYDSQACDRTCLSLSDRETECHVSPVPVDGCNCPEGTYLNHKAECVH
KAQCPC-LLDDYKFVQADQS-TMINGVICHCINGRLSCPRQAEMF-FASCPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIDCVPTKCESGCVCPKGLYENSDGQCVPAEE CPCDY
AGVSYPGGFELHTDCKTC----TCSQGRWTCQLSTQ---------CPST CVLYGEGHIIT
FDGQRFVFDGDC---EYM-------LATDDCGANSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLFITMADSNYTVSGE-EPLVHLKVKPSPLNLVLDIDIPGRLNLTLVWNKH
MSVSIKIRRA-TQDALCGLCGNANGNMKDDFETRS KYVASNELEFVNSWKESPLCGDAS-
-YAVDPCSLNTFRRSWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDACGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDFYNTHTLV-GENEYQYAQ--ES
NCTWHYQPCLCPGSLG-SFPDTNT------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHSEGTCVPCA
PPTTTLPP-TTTGSQPTTET---TISTEFHSSTSA-NTPVAPSYLPGLPTP---------
-----------------PPSAPSSTE-------ELTVWTTPKESTVSSGE----------
-----------------------------YPQTT-MAA---------TPPTSPWP-----
----PTSIPKSTPTELPVTQATSKPTASSL---SSSTKTTAE-LTESTTVT--------L
LT-LMPGMSTSQ----EGTP----------------------------------TSKIPV
TQTTTHRVPSPSITNQSTT-MFQTTTVQEAEITQTLAPS---------------TYTTND
ITKTQNLFST-----------GKTSA----------------------------------
--------------------------SYTTQHQSTSFHLTTISKWPTNGV----------
--SDTPGVHTSSGTPSSSHATHITYTPPTQVVSSI---------THSTGPPLGTSVQ---
-----------------------------TTINFPTLSA---------------------
----------------------------------PQTSLVTPHPGLSSSST-----ALTS
EIL---------------KTPTSSQMVSSASPQTI-------------------------
--FSSIH--------PKT--T---------------------------------------
----LEATTPQHTAPLITSITSSITQAQSSFSTDKTYTSQHSQPSTMT-AHQSRSLPTVT
TSTKSTMGLTGTPP--VHTTSGTTSSPQTPRTTHPFS---------TVAVS-NTKHTTGV
SLETS--------------VQTTIASPTPSAPQTSLAT--HLPFSSTSSVTPTSEVIITP
TPQHTLSSAST-STTTGNILPT---------TIGQTGSPHTSVPVIYTTSAIT-QT----
-------KT----SFSTDRTSTPTSAPHLSETSAVTAHQ----------------STPTA
VSANSIKPTMSSTGTPVVH-----------------------------------------
-------------------------------------TTSGTTSSPQTPRTTHPSTT---
--VAVSGTVHTTGLPSGTSVHTTT-NFPTHSGPQSSLSTHLPLFSTLSVTPTTEGLNTPT
SPHSLSVAST--SMPLMTVLPT-------------------------------TLE----
------------------------------------------------------------
----------------------GTRPPHTSVPVTYTTTAATQT--KSSFSTDRTSAPHLS
QPSTVTPTQSTPIP-------------------------------------ATTNSLMTT
GGLTGTPPVHTTS-GTTSSPQTPRTTHP---FSTVAVSNTTHTTGVSLETSVQTTIASPT
PSAPQTSLATHLPFSSTSSV----------------------------------------
-----TPTSEVIITPTPQHTLS-----------------------SASTSTTTGNILPT-
TIGKTGSPHTSVPVIYTTSAITQTK----TSFSTDRTSTSTSAPHLSETSAVTAHQ-STP
-TAVSANSIK----------PTMSSTGTPVV-----------------------------
--------------------HTTSGTTSSPQTPRTT--------------------HPST
TVAVSGTVH---TTGLPSGTSVHT---------TTNFPTHSGPQS-SLSTHLPLFSTLSV
TPT-TE-----GLNTPTSPHSLSAAS---TS---MPLMTVLPT-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------TLEGTRPPHTSVPVTYT-----TT
--AATQTKSSFSTDRTSTP--------HLSQSSTVTPTQPTP-I-PATTNSPMTTVGLT-
---GTPVVHT-------PSGTSSIAHTPHTTHSLPTAASSSTTLSTAPQFRTSEQSTTTF
PTPSAPQTSLVTSLPPFSTSSVSPTDEIHITSTNPHTVS---------SVSM--------
SRPVS--TI-LQTTIEVT-T---PPN-TSTPVTHST----------SATTE----AQGSF
STERTSTSYLSHPSSTTVHQST--AGPV-ITSIKSTMGVTGTPPVHTTSGTTSSPQTPHS
THPIST---AAISRTTGISGTPFRTPMKTTITFPTPSS--LQTSMATLFPPFSTSVMSS-
TEI-----FNTPTNPHSVSSAS---------------------------TSR--------
-PLSTSLPT------TIKGTGTPQT----PVSDI------------NTTSATTQAHSSFP
TTRTSTSHLSLP-SSMT--STL-----------TPASRS---ASTLQYTPTPSSVS-HSP
L----LTTP--------TASPPS--SAPTFVSPTAASTVI-SSALPTIHMTPTPSSRPTS
S-TGL-LSTSKTTSHVPTFSSFSSKSTTAHLTSLTTQAA--------TSGLLSSTMGMTN
LPSSGSP-----------------------------------------------------
---DINHTTRPPGSSPL-----------PTSAFLSRSTSPTGSS-SPSTPVSSS------
-NPDSSVSSPPS---------H--------------------------PG----TCSLQE
EEHQITYQ----GCVANVTLTRCQGFCASSVSFNKDTLQ-LESSCGCCQPLSTYKKQLSL
PCPDPDAPGQQ--LTLTLQVFSSCVCSPLQCKN---------------------------
------------------------------------------------------------
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-------------------------------

--MLRPWL---LLSCCGALLSTGLADTSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASIVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEAVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLALHKFAALQKLDDPGEICTSEDIPNTHVRQV----------Q--HAQICT
QLLTLVAP ECSV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAALRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGACTYILLQSPQLPEDGALMAVYDKSGFSQSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACASRGVLLW----------GWRSS-----------------V
DNCTVP CTGNTTFSYNSQACERTCLSLSDRATECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIINGVTCYCINGRLSCPQRPQMF-LAT CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTWQ---GLPRVGWGASRGAGHGPATHTYCLHSTCSRGRW GHIVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQPS----------TTGSRPTQVWPTTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSKHT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------ESPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----PGT----T--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-DQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGKTTEYTTPQTPHITHSPP------------VG-SLVTSTGP
MTATS--------------FQTTTIYPTPSHPQTTLPT--HVPPFSTSSVTPTTHTVIIP
THAQMSTSVSIHSTPTGTIPPQ--------TTVKSTRSTHTAPPMTATTSRTS-QD----
-------SS----SFSTAKTS----TSLHSYASSTHHPE----------------VTPTS
TTTITPKSTSTGTGTPVTH-----------------------------------------
-------------------------------------TNSATSSRTPIPITTHSPPT---
--GS--TSVSSTGPMTATSVKTTT-TYPTPSHPQTTLPTHVPAFSTSLVTPSTHTVITPT
HAQMSTSSSIHSKPTGTITSPT-------------------------------TLT----
------------------------------------------------------------
----------------------ATGSTRTAPTMTGTISGTSQA--QNSISTAKTSTSLHS
HASSTHHPEITLTS-------------------------------------TTTITPNPT
STGTGTPVVHTTL-VTSSRPPPPFTTYS---PPTVS--SPVSSTGPMTATSFQTTTTYPN
PPHPQTTFPTHIPPFSTSLV----------------------------------------
-----TPTTHTVITPTHVHLSTS----------------------TSIHSMPTGTIPPPT
ALTTTGSMHTAPSMTVTTSGTSKAP----SSFSTAKTSISFYSH----ASSTHHPE-ITP
-TSTTNITPK----------STSAGTSTP-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------VAHTTSAT
------------------------------------------------------------
----------------------------ISTTVPPTTVSATGSTHTAPPMTGT-----TS
--GSSQVHSSFSTATTSTS--------QHSHASSTHHPEITPTST--TTNNPKPTSTGT-
---GTPVTRT-------TSVTSSRPPTPFTTHS-----P--PT------------GSTPI
TSTGPTTTTLPTQVPPSSTSSVTPSTHTVITLTHAQISTSASIHST--------------
--PTD--TI-PPLT---T-HMATGSTRTALPMTGTT------------IQTS--QAHSSF
STAKTSTSLHSHASSTHHPETT-LNS--TTIIPKSTSAGTSTPVAHTTLTTISEPHTPFT
TH-----SPS-GSRPSSSTGPMTTISFKTTTAYPTPS--HPQTL-PTHVPPFSTSLVTSS
THD-----VITPTHAQMST-ST-----------------------------S-----IHS
TPTGT----------I---------PS--STTVKATGSTHTAPPMTVTTSVTSQAHSSFS
TTKTSTSL----------------------------------------------------
------------------------------------------------------------
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-------------------------------

------------------------------------------------------------
-DKSLYDFYGTCNYILAAACSPAGSPDFNVQLRRGPDRRISRIIVQVGPAVLSPGACPPL
--------------LTQEAPGGRAVLSLLSKLAEGSLGTRGPGE----------------
----------------------------------------GAEQRLAPSSRAQPGCPLPP
P--GK---LLEPHEYAALQKLDDPNEMCTYEELRTAKTMPR------------NHTQLCL
QLLKQVGPDCNV--SKDAFAARCQLDLEACSEAARPNCSCHTLSEYSRQCAMSGQRVRDW
RRPGFC S-------LG----K CPASQVYKECGAPCLKTCSNPAHSCSSFCTFGCFCPEGT
VLDDISKNHSCVPVSQ CPCVLNGVTYAPGQAMKAACR----TCRCASGQWVCAELPCPGR
CSLEGGSFVTTFDSRPYRFHGTCTYILVKSPSLPNNGTLMAVYDKSGSSHSETSLRAIIY
SSTKD--KIVISQDEFLTDDGDVKWLPYQTGNITIFRQTSTHLQMSTTFGLELVVELRPV
FQVYVKVGLQFKGNTQ---GLCGNYNGDTTDDFLTSM NIIEGTASLFVDSWRS-GNCPSA
LERETDPCSMSQLNKIC AETHCSVLVKEGALFEACHAVVNPTPFYK------RCVYQACN
YEETFPYICSALGSYARMCASMGIILT----------DWRSAV-DN CT------------
----IS CTGNQTFSYNSQACDRTCLSLADQTLECHPSDIPVDGCNCPEGTYLDHRNECVR
QSRCPC-FLEDQKFILAEQS-TIIRGIPCYCANGKLSCSGSPPNA-SESCKAPKTYLSCS
QSSDSKYGA---ACAPTCQMLATGIECVPTKCESRCVPSRLLSDTLNSSPVP--------
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ML-GVRLL--PLLFFRGGLISAGTWTGDTTD---SDNESSLQSFSDKGWCSTWGAGHFST
FDHHEYDFTGMCNYIFTATCKDASP-TFSIQMRRGPDGNISRIIIELGASVVTVNKAVIS
VRDIGVVSLPYTSNGLQITPYGQSM-RLVAKQLELELVVMWGPDDYLM------------
--------------------------------VLMERKYMDKLCGLCGNFDGKTDNEFLS
E-DG K---LLESHKYATLQKLDDPNEICAHEAIPKPTVLQ-----------T-KYAKICT
QLLTLVAP ECDV--PKEPLVLSCQADMAACDQPGQQNCSCATLSEYSRRCSTAGQPVHNW
RSPRL CP-------LG----Q CPANQVYQECGEACVRTCSNPQHSCSSFCTFGCFCPDGT
LLDDVSRNHTCVPVSQ CPCMLNGVIYGPGEVTRTACQ----TCQCTMGHWTCTERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYVLLQSPQLPNEGTLMAVYDKSGYSHSETSLMSVIY
LSKKD--KIVISEDEVITNNGDTKLLPYKTHNITIFRQTSTHLQMTTTFGLELVIQLQPV
FQVYITVGPQFRGQTR---GLCGNFNGDTKDDFTTSM GIDEGTASLFVDSWRA-GNCPTA
LERETDPCSMSQLNKVCAET HCSMLLKKGNVFEKCHTVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSSRGIVLW----------GWRSSV-DNCT------------
----VP CTGNRTFSYDSQACDRTCLSLSDRGAECYASAVPVDGCNCPEGTYLNHKGECVR
KTQ CPC-LLDGYKLVQADQS-TMINGVICYCINGRLNCPRQAEMF-LAS CPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIACVPTKCESGCACPKGLYEDSNGQCVPAEE CPCEF
SGVSYPGGAELHTDCKTC----TCSHGSWTCQQSAQ---------CPST CVLYGEGHIIT
FDGQRFVFDGNC---EYT-------LATDDCGTNSSQPTFK----VLTENVICGKSGVTC
SRAIKIFTGGLSITMADRNYTVSGE-EPLVHLQVKPSPLNLVLDMSIPGRFNLTLVWNKH
MSISIKIQRD-AQDALCGLCGNSNGNMKDDFETRS KYVASSELEFVNSWKESPLCGDVS-
-YVVEPCSQNTFRLSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDTCGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPIYCGFYNTHTLV-GENEYQYMK--EA
NCTWHYQPCLCPGSLE-NFLDTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHSQGTCVPCA
PPTTTLAP-TTTGTQPTMAT---STTTGLHSFSSP-ATSVGPFSSTSFPAP---------
-----------------SISTPSSTE-------EVPDWTTPKKSTVSSGQ----------
-----------------------------PSQSH-WKR---------VTFGRNV------
------------TLQCRLLGLLS-----------TGLFWDLQ-LAGR------------R
AADHLPGLCGQC----DSNS----------------------------------LGLLRL
LCQSQH------------------------------------------------------
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-------------------------------

---------------------------------LEEIPFFSFIVLSKDSCSTWGGGHFST
FDKYQYDFTGTCNYIFATVCDE-SSPDFNIQFRRGLDKKIARIIIELGPSVIIVEKDSIS
VRSVGVIKLPYASNGIQIAPYGRSV-RLVAKLMEMELVVMWNNEDYLMVKNNPEIHALST
--------------------------KLQNETVLTEKKYMGKTCGMCGNYDGYELNDFV S
E--GK---LLDTYKFAALQKMDDPSEICLSEEISIPAIPHK------------KYAVI CS
QLLNLVSPTCSV--PKDGFVTRCQLDMQDCSEPGQKNCTCSTLSEYSRQCAMSHQVVFNW
RTENF CS-------VG----K CSANQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGT
VLDDISKNRTCVHLEQ CPCTLNGETYAPGDTMKAACR----TCKCTMGQWNCKELPCPGR
CSLEGGSFVTTFDSRSYRFHGVCTYILMKSSSLPHNGTLMAIYEKSGYSHSETSLSAIIY
LSTKD--KIVISQNELLTDDDELKRLPYKSGDITIFKQSSMFIQMHTEFGLELVVQTSPV
FQAYVKVSAQFQGRTL---GLCGNYNGDTTDDFMT SMDITEGTASLFVDSWRA-GNCLPA
MERETDPCALSQLNKISAET HCSILTKKGTVFETCHAVVNPTPFYK------RCVYQACN
YEETFPYICSALGSYARTCSSMGLILE----------NWRNSM-DNCT------------
----IT CTGNQTFSYNTQACERTCLSLSNPTLECHPTDIPIEGCNCPKGMYLNHKNECVR
KSH CPC-YLEDRKYILPDQS-TMTGGITCYCVNGRLSCTGKLQNP-AES CKAPKKYISCS
DSLENKYGA---TCAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPPEE CPCEY
GGLSYGKGEQIQTECEIC----TCRKGKWKCVQKSR---------CSST CNLYGEGHITT
FDGQRFVFDGNC---EYI-------LAMDGCNVNRPLSSFK----IVTENVICGKSGVTC
SRSISIYLGNLTIILRDETYSISGK-NLQVKYNVKKNALHLMFDIIIPGKYNMTLIWNKH
MNFFIKISRE-TQETICGLCGNYNGNMKDDFETRS KYVASNELEFVNSWKENPLCGDVY-
-FVVDPCSKNPYRKAWAEK TCSIINSQVF------SACHNKVNRMPYYEACVRDSCGCDI
GGDCECMCDAIAVYAMACLDKGICIDWRTPEFCPVYCEYYNSHRKTGSGGAYSYGS--SV
NCTWHYRPCNCPNQYY--------------------------------------------
------------------------------------------------------------
--------------------------------KYVNIEGCYNCSHDEYFDYEKEKCMPCA
MQPTS-VTLPTAT-QPT-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------SPSTSS---AST-----VLTETTN------------------
------------------------------------------------------------
----------------PPVTSKITVSRTSSSSPLVTIKSTTEHTTSIFTMPSMTT-TVTA
PSITTSAKRTIFTEPKSTPTASATTASVETEKISFTTPLLETTVKKE---M--TT-I-S-
IPYTTSQIATFSKPELTTRPFS--TN--------S---------LPPRKCTNL-E-----
----------------RI-F-C--F-P-Q-K-------V-QE-D--A-EG--T-E-L-V-
---------------QFLP-HIL-G--------RS-R-KG--------------------
----------------KVRDEA----------TVKSQPA-FC------------------
----------------------------APSPA-------------------------RV
---FC-LG-SLHS-LH-LPF--------L-SYH-LQFI-CAFLP----------VAVT--
-HKRP-TTPHATTVPPLTTE---KTTPITSFTSTSRTSV-F-------------------
-SEASPTSSPEIPL---T--------------TTSP-------------APSSTLSTRLP
TPAPSTLFSTL-PPISMPKTVPTTLRPKPSSPTTSASTELLIPASS------------TP
STAKTSLLPSSASSPYST------------------------------------------
--------------VSSTVLS----TS-HPACLIFLHLLIFNI-----------------
--------------------------------------QRTCACFSA-------------
----------TSTHKKTTVLHVVPYIITEKTTP-----TMSTTSTSKT------------
SISSKATSTSSPE----VPLTTTS------PALSSTLSTRLSSPVP-STLFS--------
-----TSPS------TS----------TPKPTST---TLRLKPSSLTTSAP---------
--AESPTTVFV--------------------------------IPSTAKTSLLPSV-SSP
LSTV----------S-------------------STAMKTSQP-----------------
-----------------------------------------------------------T
STHKMTTVPHIVPSVTTEKTTPTVSATSTSKTSISSEASPTSSPEIPLTTTSS-------
--APSITLSTSLPSAAPST-LF---------------------------STLLPTSTPKS
-------------TPTT--------------------------------LRP--------
-----------KLSPLTTSAPTESPTPASSTLSTAKTSL------------LPSSAS---
-------SPFSTIS------STVRTTSLPAS-----------------------------
----------------------------------THKM-----TTVPHIVPSVTTEKTTP
TVSATSTSKTSISSE-ASLTSSPEIPLTTTS------SAPSSTLSTSLPSAAPSTL----
---SSTTKLRPTTLRPKPSSMSTSAPTE-------SP-----T-----PASSTPSTAKTS
LLSLSPSSF-STVSSTAMST-------------SYPS-----------------------
------------------------------------------------------------
---------------------------------------------KSPSCP---------
------------------------------------------------------------
------------------------------SHCSAWSSH-----RTFLPYSTNHTVVTLF
DSTTHKMTTLLHMVPYITTEKTTPTTSSVSTSK-------TSIS--------KIPLTTTS
SAPSSTLSTRLQTP-APSTLLSTLPSPSTPKPTPTTLRLKPSSLTTSAPTESPTPASSTL
STAKTSLLPS--SASS----------PFSTIS--STVRTTSLPGMYSS---CSSRWCFSM
RT------------------------------------AHLFC-YFFLALPLSIELSTST
HKKTTVLHVVPYIFTEKTTVMPATTSISKTSISSEASPTSSPEVPLTT------TFPAPS
SALSTRLPSAASSTLFST-SPPTSTPEPTLTTLSPST----FLS-----SESATYSSS--
THNTTFSFTP----PGETFSVAFPTAASAKS--SPVVIPSLLPTTIKFAPS---------
-M----------T------------TTASTEIPSIEQTSIQTTTLTTT-H--------TT
SSLS------VT-----SG--LSTSLS---------------------------PVRPST
VPQGKQASCSALM-------------FTWGGG----------------------------
--AVINVFIREPDENHAGYGDDQKK---VDQYVLLSKWHYA---F---------------
----------NLEMKYLSFKTLKQNLKND---QIKNFS--------SPLHPSSKFCKKVE
YEENITYK----GCSANVTLSRCEGLCPSSTKLNVENMV-FSAACSCCRPLQLHKEKFQL
PCEDPDNPGK--RLTKEITVFGGCVCN-FDSCIQ--------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

--MVQWWL---LLSCCGALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYLFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEVVWGPDSHLMV-----------
---------------------------------LVEQKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTFQDIPSTHVRQA----------QHARI--CT
QLLTLVAP ECSV--SKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSNNHTCVPVTQ CPCVLHGAMYAPGEVTIAAC----QTCRCTLGRWACTERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTYLQMATSFGLELVVQLRPI
FQAYVTVGPQFRGQTR---GLCGNFNGDTTDDFTTSM GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-DNCT------------
----IP CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNHKGECVR
KAQ CPC-ILEGYKFILAEQS-TVINGVTCHCINGRLSCLQRPQMF-LAS CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----SCSRGRWACQLGTH---------CPST CTLYGEGHVIT
FDGQRFVFDGNC---EYI-------LATDVCGVNNSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRH
MTVLIRIARA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-GHGEYQYTQ--EA
NCTWHYQPCLCPSQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PPTTPQPP-TTP---QPPTTGSRPTQVWPMTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSNRT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------RSRATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTA--------QL----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTRTTTEYTTPQTPHTTHSPP---------T--AG-SPVASTGP
VTATS--------------FHATTTYPTPSHPETTLLT--HVPPFSTSLVTPITHTVITP
THPQMSTSAYVHSTPTGTIPPP--------TTVKATGSTHTAPPMTVTTSGTS-QA----
-------LS----SFNTAKTS----TSLHSHTSSAHHPE----------------VTPTS
TTTINPKHTTTGTRTPVAH-----------------------------------------
-------------------------------------TTLATSSRLPTPFTTHSPPT---
--RS--SPISSTGPVTATSFQTTT-TYPTPSHTQTTLPTHIPPFSTSLVTPSTHTVITPT
HQQMATSASIHSMPTGTIPPLT-------------------------------TLK----
------------------------------------------------------------
----------------------ATRSTHTAPPMTPTTSGTSQA--RSSFSTAKTSTSLHS
HTSSTHHPEVTPTS-------------------------------------TTIT-PKP-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------TTPSMTATTSGTSQSP----SSFSTAKTSTSLPYH----TSSTHHPE-VTP
-TST-TITPK----------PTSTETGNPVA-----------------------------
--------------------DTTSATSSRLPTPFTT--------------------HSPP
TGSSP--FS---STGPMTATSFQT---------TTTYPTPTHPHT-TLPTHIPPFSTSLV
TPS-TH-----TVITTTHAQLSTSASIHSMPTGTIPPPTTLKTTGS--THTAPPMTPTTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAPSSFSTAKTSTS--------LHSHTSSTHHPEVTPTST--TNITTNPTSIGT-
---GIPVAQT-------TSATSSTLPTSFTTHSPPTGSS--PISSTGPVTATSFQTTTTY
PTPSHPHTTLPTHVPPFSTSLVTPSTHTVITATHAQMATSASIHSM--------------
--PTG--TI-LPPT---T-LKATGSTHTAPPMTPTT------------SGTS--QAPSSF
GTAKTSTSLHSHTSSAHHPEV-TPTST--TITPKPTSTATRTPLSHTTLTTSSRLTTPFT
TH-----SPSTGSSPISSTAPVTATSFQNTTTYPTPSHS--ETTLPTHIPPFSTSLVTPS
THT-----VITTTHA---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------Q--------MATSASIHS
TPTGTIPPLTT-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------LKATGFNIITQQ-VDAHCSCCRPLHSYEQQLEL
PCPDPSTPGRR--LVLTLQVFSHCVCSSVACGD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

------------------------------------------SGSDKGICSTWGANHFFT
FDNDLYQFSGSCNYVLATVCQS-TTPEFNIQVQRSGGASITRIIIQIGLINVVVQGSTTV
-VLGRTIALPYTANGIEITKTGAVT-RLYAKQKDFELIVTWSTDGNLMV-----------
---------------------------------EVDQRFMNRICGLCGNYNGIPKDDFMV
D--GK---LAMPYQFANLHQIDDPGVTCPFQVPPGKTAP KK------------SYTEECY
SLLKKVSSSCSV--SRIPFLKLCQLDMQSCARPGDASCVCATLAQYSMRCAMCNQPINNW
RTKQLC P-------LE----A CPANQIYRECAAPCSPTCSNPTYTCSSHCVHGCFCPPGT
VLDDLSKNLTCVPVSQ CPCVVNGKRYYPGERIKSDCS----DCKCHMGQWSCTSTPCPGR
CSLEGGSFVTTFDTNMYRFHGDCVYILVTNRNPDNQWTIMATFEKCGTSSTETCLESIIY
TASTG--AIVMSKEDHITVDSQIKQLPFNSEEVNVIRVSSTNFALSTKFGLEIVIHRAPV
LNVYIKMSRSYFGTTK---GLCGNFNGETMDDFMSSSG VIEGTIPIFVDSWKAASNCLPA
QNSDVNPCSLSYSN ENYAKSHCSALMNSNSPFAACSALVNLDQYYT------KCVYEACN
YQETNNFICSAMASYARACAAKGVILQ----------NWRES--TNCT------------
----VQCPGNQTYSYNTTSCGRTCLSLSNKELECYPNDIPVEGCNCPTGFYLDNKNMCVR
KESCPC-YLDANTILLPQQQ-TTYNGLTCICSSGSLNCIGFLQAA-QESCPAPKMMKTCD
-SLTDKYGA---ACAPTCQLLATGISCIPTKCVSGCVCPSGTYEDLDGNCVNQTDCSCEF
GGEIYKTGDTMQSECQSC----TCNGGHWNCEANLN---------CASTCVLYGESHIKT
FDGQQFVFEGNC---EYT-------LVTDGCGVNNSLSSFK----IVSENVVCGTTGVTC
SRAITAFIGDTTLKMFDEKYTVTGV-ND---IKVLNNTLFIEFVITIPHKFKISILWNKD
MNVFIKVFKL-GKQSVCGLCGNYNGNVKDDYQTRSK YVTSNALDFINSWKESPMCNNVR-
-LIVSPCDANPHR KPWATSSCSIINSQTF------DACHKVVNSQLYYESCVNDACGCDT
GGDCTCMCDAVQAYAKACLAAGVCVDWRTPDFCPVYCDYKNTHVSTGDGYVYS----PDV
NCTWHYQPCQCPFALQA-------------------------------------------
------------------------------------------------------------
-------------------------------YPHQNFEGCYQCGPDKYFDPEQNTCLPCV
EHSTTTIEPSTSGTSGT-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

--MLQPWL---LLCFCGALLGAGLPD-AYASPGPQRPKDSPQTAPDKGRCSTWGAGHFST
FDHHVYDFSGTCNYVFAATCKDAFP-TFSVQLRRGLDGSIARIIVELGASVVTVSEGTIS
VKDIGVISPPYTSNGLQITPFGQSM-RLVARQLELELEVMWGPDAHLMV-----------
---------------------------------LVEQKYMGQMCGLCGNFDGKATNEFIS
E-E GK---LLEPHKFAALQNEGAPGGLIPGLT-------------------SAPQARICT
QLVTLVAP ECSV--PKEPFVLSCQADMAAATQPGPGNSSCATLSEYSRQCSMERQPVRRW
RGPSL CP-------VG----Q CPANQVYEECGSACVKTCSNPQHSCSSTCTFGCFCPEGT
VLNDLSNNHTCVPVTQ CPCVLNGATYAPGAVTTAACR----TCQCTLGRWACTERPCPGH
CSLEGSSFVTTFDARPYRFHGTCTYILLQSPQLPENGTLMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVSNNGAAKWLPYRTRNITVFRQTSTHLQMVTSFGLELVVQLRPI
FQAYITVGPQFRGQTR---GLCGNFNADTTDDFTTS LGIPEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHTTVNPTPFYK------RCVYQACN
YEETFPHICAALGDYVHACASRGVLLW----------GWRSSV-ENCT------------
----VP CTGNSTFSYDSRVCERTCLSLSDRTAECHASAVPVDGCNCPDGTYLNHKGECVH
KAQ CPC-TLEGYKFILAQQA-TVINGATCYCINGRLSCPQRPQMF-LAS CPTPKTFESCS
QSSENVFGA---ACAPTCQMLATGVACVPTKCEPGCVCAKGLYENADGQCVPPEE CPCEF
SGVSYPGGADDHTHTHTCRLHSTCSRGRWACQQATH---------CPST CTLYGEGHIVT
FDGQRFVFDGSC---EYI-------LAMDGCGANDSQPTFK----ILTENVVCGKAGVTC
SRAIKLFLGGLSVVLADRNYTVSGE-EPHVQLRVRPDALSLAVDVGVPGRYNLTLVWNRH
MTVLIRITRA-SQDTICGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSVINSQTF------ATCHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-GHGEYQHTE--EA
NCTWHYQPCLCPGQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCMPCM
PPSTPQPP-TT----GLPHSGSRPTQVWPTTGTA---TTIRLLSSTGGPSP---------
------------------------------------------------------------
-----------------------------SSKST-TA----------GPTQTPI------
---------------LPATLTPSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPLRPTTAITPQATSGQMPTATL-----------------RSTATK
PIVTQATTRAT------APTTSPA------------------------------------
-----TKSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PTPAA-----SGTSPTLA--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-HQELPGTTATRTTGP--RP---------------------------
----------------------------TAASTAGPTTPQPEQPT-------------R-
----PTA--TERTT--HTRTTTEDTTPPTPFTTHSPP---------T--GS-RPTSSTAP
VTATS--------------FKTTTTHPTPPHPQTTLPT--HVPPFSTSSVTPSTHTVITP
THPPMSTSPSTHSIPTGTVPVP--------TTVKATVSTHTAPPMTATTSETS-QA----
-------HS----SFSTATTS----TSLHSHAISTHHPE----------------TTPTS
STTITPKTTSRGTSTPVAT-----------------------------------------
-------------------------------------TTSATSSRPPTPFTTHSPPT---
--GS--RPISSIGPMTATSFKTTT-THPTAPHPPTTLSTHIPPFSTSSVTPSTHKIITPT
HPPISTSPSIHSTPTGTVPVPT-------------------------------TVK----
------------------------------------------------------------
----------------------VTGTTHTAPPMTATTSGTSHA--QSSFSTATTSTSFHS
HGFSTHYPEITPTS-------------------------------------STTITPKPT
GTG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------TTPPMTATTSGTSQAH----SSFSTATTPTSLQSH----ASSTHHPE-TTP
-TSSTTITPK----------TTTRGTGTPVA-----------------------------
--------------------ITTSATSSQPPTPFTT--------------------HSSP
TGSRP--IS---STGPMTATSFET---------TATHQTPPHPQT-TLTTHVPPFSTSSV
TLS-TH-----KIITPTHPLISTFPSIHSTPTGTVPVPTTVKVTGT--THTAPPMTATTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAQSSFSTATTSPT--------LSSHASSTHYPETAPTPT--TTITPRPTGTGT-
---GTPVAHS-------TSATSQRPPTPFTTHSPPTGSK--PVSSTGPMTATSFKTTTTH
PTPPHPHTTLSTHIPPFSTSPVTLSTHTVITTTHPPMSTSLSIHST--------------
--PTG--TV-PVPT---T-IKVTGTTHTAPPITATT------------SGTS--QAHSSF
STATTSISLHSHASSTHHLET-TPTSTTTIT-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------PKTTSRGTGTP
VATTTSA-----------------------------------------------------
--------------------NLS-------STGLHQGRPRLGQ--------EGSEAGGDV
VPS---------------------------------------------------------
---------QGPPPSS-----------------LHAT-----------------------
---LGAADCPTL---------L--------------------------PG----VCSVQE
QQEEITFK----GCVANVTMTRCEGVCISSASFNIDIQQ-LDARCSCCRPLHSHEQQLEL
PCPDPSAPGRR--LVLTLQVFSRCVCSSVSCGH---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

MLRVQQLL--LLLLFRGPLIDAGAWTGDVTD---SNTEDNLQSSPEKGWCSTWGTGHFST
FDGHEYNFQGMCNYIFTATCGDDVPATFSIQLRRDMDGNISRIIMELGASVVTVNKETIS
VRDIGVVSLPYTSNGLQITPYGQSV-QLVAKQLELELVITWGPDAHLT------------
--------------------------------VQVETKYMGKLCGLCGNFDGKIDNEFLS
E-DG K---LLEAHKYATLQKLDDPNEICAHEAIPSTIILK-----------T-RYAQICN
QLLTLVSPG CDV--PKETLMLSCQADMAACARPGQPNCSCATLSEYSRRCSMTGQPVRNW
RTPAL CP-------MS----Q CPANQVYQECGEVCVKTCSNPQHSCSSPCTFGCFCPHGT
LLDDISGNQSCVPVNQ CSCMLNGMVYGPGEVTKTACQ----TCQCTTGRWTCTKQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPNEGTLMAVYDKSGYSHSETSLVAIMY
LSKKD--KIVISEDEVITNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLELVFQMQPV
FQVYITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GIDEGTASLFVDSWRA-GNCPAA
LEREMDPCSMSQLNKVCAET HCSMLLKKGSVFEKCHSAVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSARGILLW----------GWRNSV-DN CT------------
----VP CTGNRTFSYDSQACDRTCLSLSDRETECHVSPVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDDYKFVQADQS-TMINGVICHCINGRLSCPRQAEMF-FAS CPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIDCVPTKCESGCVCPKGLYENSDGQCVTAEE CPCDY
AGVSYPGGFELHTDCKTC----TCSQGRWTCQLSTQ---------CPST CVLYGEGHIIT
FDGQRFVFDGDC---EYT-------LATDDCGANSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLFITMADSNYTVSGE-EPLVHLKVKPSPLNLVLDIDIPGRLNLTLVWNKH
MSVSIKFRRA-TQDALCGLCGNANGNMKDDFETRS KYVASNELEFVNSWKESPLCGDAS-
-YAVDPCSLNTFRRSWAER KCNIINSQTF------AVCHSKVYHLPYYEACVRDACGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDFYNTHTLV-GENEYQYAH--ES
NCTWHYQPCLCPGSLG-SFPDTNT------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHSEGTCVPCA
PPTTTLPP-TTTGSQPTTET---TISTEFHSSTSA-NTPVGPSYLPGLPTP---------
-----------------PPSAPSSTE-------ELTVWTTPKESTVSSGE----------
-----------------------------YPQTT-MAA---------TPPTSPWP-----
----PTSIPKSTPTGLPVTQATSKPTASSL---SSSTKTTAE-LTESTTVT--------L
LT-LMPGMSTSQ----DKTS----------------------------------ASY---
------------------------------------------------------------
------------------------------------------------------------
----------------------------TTQHQSTSFHLTTISNWPTNGP----------
--QHFSH------------WKLLTYYPSITLQSRL---------LGLLATLASWDLQLT-
--------------------------GRRAPDYLPGLCG---------------------
----------------------------------QCDS--NSLPGFLRLLC-----QFQ-
------------------------------------------------------------
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-------------------------------

------------------LAHTGLNETSFVHPDLQRLQNSSQTAPDRGWCSTWGAGHFST
FDGHVYDFLGTCNYIFAATCKDTSP-TFSVQLRRGPGGGISRVIVELGVSVVTVQKAVIS
VKDVGVVGLPYTSNGLQITPFGQNV-QLVAKQLELELVVMWGPGTHLM------------
--------------------------------VLVEKRHMGKLCGLCGDFNGEQTNEFLS
E-E GK---FLEPHTYAALQTLDDPDEICTYKAVPNPQVPQA------------EHAQTCT
QLLTLVAPECNV--PKEPFMWSCQVDMAECVLRGQHNCSCATLSEYSRQCSMAGQAVSNW
RGPGLC P-------VG----T CPANQVYQECGETCVKTCSNPQHTCSSFCTFGCFCPKGT
VLDDISRNHTCVPVTQ CPCMLNGVVYAPGEVVTAACQ----TCQCTTGHWKCTEQPCPQR
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPDGASLVASYDKSGYSHSETALAAIIY
MSRED--KIVISQDEVFTHNGNTKWLPYKTRNITVFRQTSTHIQMTTTFGLELVIQLEPV
FQAYITIGPQFRGQTR---GLCGTFNGDTTDDFMAST GIVEGTASLFVDSWRT-GNCPAS
LERETDPCSMSQLNKVC AETHCSVLVRNGSVFEKCHAMVNPRPFYK------RCVYQACN
YEKTILHVCAALSDYARVCATRGILLR----------DWRNSV-DNCT------------
----TPCTGNQTFGYDTRACGRTCLSLSDHAAECHPSAVPVDGCNCPEGTYLNHKAQCVR
KSQCPC-LLDSNKFILADQS-AMVNGVICYCINGRLSCPGRPQML-LATCSAPKTFQSCN
ESSENTFGA---ACAPTCQMLATGTPCVPTRCEPGCVCAEGLYENANGQCVPPEE CPCEF
AGASYPPGAELHTDCRTC----TCSRGKWTCWQSAR--------C-SST CALYGEGHVVT
FDGQRFMFDGSC---GYILTT-------DGCGANNSRPTFT----VLTENVVCGKSGVTC
SRSIKISLGGLSIVLADRNYTVSGE-DPHVHFRVNAGSLNLVLDITISNRYNLTLVWNKH
MTIFIKITRA-TQDALCGLCGNYNGNMKDDFETRS NYVASSELEFVNSWKDSPLCGDTS-
-LALDPCSLNTFRR AWAERKCGIINSPTF------AACHSQVYHLPYYEACVQDACGCDT
TGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDYYNTHTH--EDGAYQYNQ--DA
NCTWHYQPCLCPQHPQ-SLPHTNTEG----------------------------------
------------------------------------------------------------
---------------------------------------CYNCSQDEYFDQNTGTCVPCM
SPPTTPRP-TTGTESP------------------------------VLEARA---QIP--
-KNNPSQNV-TALCCLDPNPT---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PPHPAE--------P---------------------------------------LP
AAQTTQWERAEGSGESPRSISAITPRATSAPTPMTTL-----------------KSTATG
PTETQTTMKFTASMF------SSA------------------------------------
-----MQSTARSTEHTTAAPRTKEISETSRGPPTS---KQTPYACLQKGETHKR----GH
QPSTNPEH----TIQTILLQCFTEKVPQLLTTTTHPPQVTRRK----QPSQG-QNRWSK-
------QEHTNPNKNNLL------TQDRGPVGKRHTNKA------RNTATTEP-------
--TGASP-----------------------------------------------------
------------KHTSI---RNTPMITETKSMETIR----------SQETTV--------
------------------------------------------------------------
-----------------------------------------------------TENSQLT
THYLPHTHETT---TETSRITNTPLTLHTTHTFHPTP---------SPAVPTNTLHTTGS
PTGTS--------------FRTTTGFPSPSHAETTLST--HMSATSTSSVTPTSHLVISP
TYEPTPSPHSTARHTGTPSPSP-------HSPGTGTQPTHTKPPLTRTTVTPT-------
------S-------VSTVKTS----TSPRSHPTSPIHQEASSAHPT--------------
--TISNHPPRTL--TTTSWTRSAATSKPHTPHTSHAASSPAV------------------
--------PTSTVHT--TGTPTGTSFRTVTTTSWTRSAATSKSHTPHTSHATSSPAVP--
-----TSTVHSTGPPTGTSFRTTT-AFPSPSSSETTISSHASASTTSSVTSTSHLII---
--S---------------------PTHQPTPSPHST----------------ARHTGTPS
PSPHSP------GTG-TQPTHTKPPLTRTTATPTSVSTV---------K--TSTSRPSHP
------------------------------------------------------TSPIHQ
EVSSVHTSAFP-------------------------------------------------
-----------------------------------------------------------S
PSHPGTTLSMHTSAST--------------------------------------------
-TASVTPTSHLVITPTYEPTPSPYSTARHTRTSTSTMSSVSRTSHIFISPTQQPMPSPIS
TATHTGSPTPSP------------------FFSS---------------SS-----SISH
-TLTSSSSPSTSITASVSSIVYSSGASIPML-----------------------------
--------------------SS---RSSPSPHTFLP----------STLPTKPLPH----
-VS-PSSVS---------STIIPP---------SSTKTTPSTPFSHNLSSHSTTSQSTSL
T--------------TR---NPTSGIFS-STMGITS-----------------PTTNLTT
G----PSTISRLPTT-VILTTP--TSRHGSS--TLPN-------IGSLSTVGPSVSS---
------LVTSPSSSTGVCDVKELE------EEVTYRGCTANVTVTRCEG-----SCPASA
------SFNIYTNQVDTHC---S-CCHPVSS--YQ-------KQFVLPCSDPEVLGQQLV
LTLQMFSS-----C---------ACSPQHCGV----------------------------
------------------------------------------------------------
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-------------------------------

--------------------------------------------LSQGWCSTWGAGHFST
FDKYLYDFSGTCNYIFAA-----SPPDFDIQLQGG--RHISRIIIEVGPSLITVENSVIS
IKDCGVVSLPYTFNGIQIMPFGQNV-RLVAKLLEMELVVMWNNDDYLMV-----------
---------------------------------MVEKKYMKKTFGLCGNFDEEESNERA-
K--GK---L LDLYRYAAQQKMDDPTHICAY EELPI---------------------QLCL
QLLTQVGPNCNV--SKYDFAARCQLDLEACPEPVQPNCSCPTLSEYSRQCSMSGQPVTNW
RRPSLC R-------LG----E CPANQVYQECGTPCMKTCSNPAHSCPSFCTFGCFCPE DT
TSQDRNDRGFY-------------------ALVPVTQ----HSQCTSGEWICTELPCPGR
CSLEGGSFITTFDSRHYRFHGTCTYILVKSPSLPNNGTLMAVYDKSGYSHSETSLMGVIY
SSAKD--KIVISQDDLLIDDGDVKWLPYKAGDITIFRQTSTHLQMSTTFGLELVVQLRPV
FQVYVKVGLQFKGNTR---GLCGNYNGDTTDDFLSSMD IIEGTASLFVDSWRL-GNCPSA
LERETDPCSMSQLN KICAETYCSILMKKGTVFEACHATVNPAPFYK------RCVYQACN
YEETFPYICSALGSYARMCASMGLILN----------DWRSTV-DNCT------------
----VSCTGNQTFSYDSQACNRTCLSLADHTLECHPSDIPVDGCNCPEGTYLDHRSECVR
QSRCPC-FLEDRKFILADQS-TIISGIPXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXX---XXXXXXXXXXXXXXXVPTKCESGCVCDDGLYENLNGDCVPPDDCPCEF
GGLSYNRGDQIQTKCLAC----TCIRGKWQCLKKDK---------CFSTCALYGEGHLTT
FDGQHFVFDGNC---EYV-------LTTDGCGTNSN-PTFK----IVTENVICGKSGVTC
SRAIKLFLGDQVLILSDASYTITGK-NPQGHIQVKKNALHLMFDVTIPGKFNLTLIWNKR
MSIFIKMFRD-SQDPLCGLCGNYNDNMKDDFETRSK YVTSSELEFVNSXXXNPLCGDIT-
-FVVDPCVQNPYR KAWAEKKCAIINSNTF------SACHSKVYRMPYYDACVRDTCGCDT
GGDXXXMCDAVAAYAKACLDVGVCVDWRAPDFCPPYCDFFNTHKLISEDGSYQYSR--ES
NCTWHYQPCLCPFQSQR-------------------------------------------
------------------------------------------------------------
-------------------------------DKHINIEGCYNCTQDQYFDHEEGQCVPCX
XXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXX-----XXXX---------
XXXXXXXXXXXXXXXXXXX--------------XXXXXXXXXX---XXXXX---XXXXXX
-------------------XXXXXXXXXXXXXX--XXX--------------XX------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXX------------------
------------------------------------------------------------
----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX------XX-------XXXXXXXXXXXXXXX---
---------------XXXXXXXXXXXXXXXX------XXXXXXXXXXXXX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXX----XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX--XXXXXX-XXXXXXXXXXXXXXXXXXX-------XX
XXXXXXXXXXXXXXXXX---------XXXXXXXXX------------XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXX-------XXXX--
-XXXX-XXXXXXXXXXXXXX---XXXXXXXXXXXPSSPV-S-------------------
-SGPTSSQ-P--------------SLPPTASTFEPPSRTTLSSSSPSLHPPSNTVSEHFP
FPMSSTGFSSISPPAM------GSLSPSSSSSHRST------SASG------------SP
SY----SVP---------------------------------------------------
----------------------------PPHSAFTTPMSSFPQSTLTPFTPSHPATTSLF
T-RTIPYPSTPSIS--------STVSSPPASMTPANFLQHTCSTHSTQFTTSQSTM----
--------------------HT--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-TRV----------S-------------------AAIMASSTL-----------------
------GL--------------SACS--------------V--KEYIAEITFQG--CTVN
TT----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------LTRCEGYCPSSV-------------------------------
------------------------------------------------------------
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-------------------------------

MLGPKLLLL-LLLLLPCLACAPASWVGQEAS---R-SCHSLSAAPDKGWCSTWGTSHFST
FDHHAYDFSGTCNYVFAAICKDALP-AFSVQLRRGLDGSISRIIVELGASAVTVDNGTIS
IKDMGVVSLPYTSNGLQITPYGPSV-RLVAKQLELELVVLWG GAVGVTWVGTHVL----H
PHR-QQR-GLGWWPFP--------LLKIRRTQ-QDL EKYMGQMCGLCGDFDGNVENDFIS
E-DG K---LLESHKFAALQKLDDPNEICAYEDVPKAPSLR---------------AETCA
RLLALVSP ECDV--PKEPLAHSCQADMAACNPPGQPNCSCATLSEFSRRCSMAGQPVSRW
RGP A----------LG----L CPASQEYRECGAACTETCSNPRHSCPSSCTFGCFCPEGT
VLNDLSTNRTCVPLSQ CPCMFNGAVYGPSEVTAAACR----TCQCTTGRWMCTEKPCPGT
CSLEGGSFLTTFDTRPYRFHGTCTYILLQSPQLPDEGTLMAVYDKSGYSHSETSLTAVIY
LSRKD--KIVISEDEVITNHGDTKWLPYKTRNITIFRQTSTHLQMATTFGLELVVQLRPI
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFMTSM GINEGTATLFVDSWRA-GNCPAA
LERETNPCSMSQLNKVCAES HCSELVRKGGAFEKCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGTYAQACATQGVPLW----------GWRNSV-DNCT------------
----VP CTGNRTFSYDSRACGRTCLSLSDREAECHASAVPVDGCNCPEGTYLDHKGECVH
KAQ CPC-LLESSKFLPADQA-TLLNGVSCYCTNGRMSCSGQPQMF-LAS CPATKTFQSCD
QSAEDKFGA---ACAPTCQMLATGTACVPTKCEPGCVCAKGLYENPSGECVPAEQ CPCDF
AGVSYPGGAELHTDCKTC----TCLQGRWACQQGAH---------CPST CVLYGEGHVVT
FDGQRFVFDGNC---KYI-------LATDDCGTNNSQPTFK----VLTENIICGKSGVTC
SRAIETVLGGLSITMADSSYTVRGE-DPQVHFQVQSSALSLVLDADIPGRLNLTLVWNKH
MSVSIKVHRT-SQDALCGLCGNANGNTKDDFETR SRYVASSELEFVNSWKESPLCGDTR-
-AAVEPCSLNAFRRSWAER KCSIINGQTF------ASCHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAQACLDKGVCVDWRAPDFCPIYCDFYNTHPQA-G-SQYQPTQ--ED
DCLWHYRPCLCPGSLQ-NFEGTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHSEGTCMPCE
SSPTTTAV-TTT-----------ATSSWVPT-ITVMSTATGNTVTTATTEPTASSRSPAS
TSTARTTART-TVVPLT----VTTW-ATTPGQ--GEPWDTMTRSTAQ---HG--------
-------RVSLGEYQDFPTGQAGRTGPRTSS----MNTK-------TTPSTPPITMTTSA
TSQVPTSLSTARTLPVHVTQPSSTPHRESTSSLSPTVTSHPTSTETHTTMAHTTSSMTTR
AISHTPHTTGST----SGTSLKT-------------------------------TTNFPT
TS--STQTPTPSI-SPTLT-TAVVSPTSQRTPPSTHT-----------------VSSAST
M-RPTGTKQPASMNTKTTPSTPPITM---------------TT-----------------
-SATSQVPTSLSTARTL--PVHVTQPSSTPHRESTSSLSPTVTSHPTSTETHTTMAH--T
TSSMTT----------RASTPFSTHTPSTLSVSHT---------PHTTGSTSGTSLK---
-----------------------------TTTNFPTTSSTQTPTPSISPTLTTAVV--SP
TSQRTPPSTHTVSSASTMRPTGTKQPASMNTKTTPSTPPITMTTSATSQVPTALSTARTS
PIHVTQPSSTPHRESTFSLSPTTISYPTSTETHTMSSTLTRASTPVSTHTPSTLSVSQAP
HTTGSTSGTSLKT-TTNFPTTSSTQASTPSVSPTL-TTAVVTPPISS----ASTMRPTST
TQSTTMVTTATHSTPPITMTTSATTQLPTSLSTARTSPVHVTQPSSTPHQES------TS
SLSPNITSHPTSTE--THTTSSTLTRASTPVSTHTPS---------TLSVS-HAPHTTGS
SSETS--------------LKTTTNFPTTSGTQTPTPS--ISPTLTTALYSPTSQRTPPS
T-------YTV-SSPST-----MRTTGTKQPASMITKTTPSTPPITMTTSATS-QV----
-------PT----TLSTARTS----PIHVTQPSSTPHRE----------------STFSL
SPTTISYPTSTETHT---------------------------------------------
--------------------------------------TSSTPTRASTPVSTHTPST---
--LSVSHTPHTTGSTSGTSLKTTT-NFPTTSGTQTPSPSASPTLTTAVVSPTSQR--TPP
STHTVSSAS--TMRPTSTTQPA-------------------------------TMV----
------------------------------------------------------------
-----------------------TTTTHSTTPITMTTSATTQV--PTSLSTARTSPVHVT
QPSSTPHQESTSSLSPTVTSHPT----------------------------ST-------
--ETHTTMAHTTS-SIPTRASTPFSTHT---PSTLSVSHTPHTTGSTSGTSLKTTTNFPT
TSRTQTSSPTVSPTLTTAVV----------------------------------------
-----SPTSQRTP-PSTH-TVS-----------------------SASTMRPTSTTQSTT
MV--TTATHSTPPITMTTSATTQVP----TSLSTARTSPVHVTQ----PSSTPHRE-STS
-SLSPTVTSH----------PTSTETHTTMA-----------------------------
--------------------HTTSSIPTRASTPFST--------------------HTPS
TLSVSHTPH---TTGSTSGTSLKT---------TTNFPTTSRSQT-SSPTVSPTLTTAVV
SPT-SQ-----R--TPPSTHTVSSAS---TMRPTS---TTQST-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------TMVTTATHSTPPITMT-----TS
--ATTQVPTSLSTARTSPV--------HVTQPSSTPHRESTSSLSPTVTSHPT--STET-
---HTTMAHT-------TSSIPTRASTPFSTHTPSTLSVSHTPHTTGSTSGTSLKTTTNF
PTTSRSQTSSPTVSPTLTTAVVSPTS--QRTPPSTHTVS-----------------SAST
MRPTS--TT-QST----T-MVTTATH-STPPITMTT-SATTQVP--T--------SLS--
-TARTSPVHVTQPSSTPHRESTSSLSPT-VTS------------------------HPTS
TETHTTM------AHTTSSI-PTR----DPHHHPFPCL--FLPFLL-LCLPPSCHLS-RC
LSS-------LPCPPHPLCTCPL-P----------QPP-------AQHLCPR-----PGP
HPRSPCPP------------------------LS-----PLRPPLPR-------------
-----LPFLP---PRPL----------------------CLAQCPQPWGQYPPHTL-HPP
T----SPPG--------TLGPPS--CPH----P------H-SCPAQLLHIHPR-------
--PPP-WNFCPPSAPG--YPLW--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

--MVQRWL---LLSCFGALLSAGLANTSYTSPGLQRLKDSPQTAQDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEVVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTFQDIPSTHVRQA----------QHARI--CT
QLLTLVAP ECSV--SKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACLKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSNNHTCVPVTQ CPCVLHGAMYAPGEVTIAAC----QTCRCTLGRWACTERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPENGALMAVYDKSGFSHSETTLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI
FQAYVTVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIVEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-DNCT------------
----IP CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNHKDECVR
KAQ CPC-ILEGYKFILAEQS-TVINGVTCHCINGRLSCLQRAQMF-LAS CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGASYPGGAELHTDCSTC----TCSRGRWACQQGAH---------CPST CTLYGEGHVIT
FDGQRFVFDGNC---EYI-------LATDVCGVNDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLRVTPGALSLVVDISIPGRYNLTLIWNRH
MTVLIRIARA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRSSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-GHGEYQYTQ--EA
NCTWHYQPCLCPSQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PPTTPQPP-TTP---QPPTTGSRPTQVWPMTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSNGT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTMTL----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----SGTSPTL---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------FQTTTTYPTPSHPQTTLPT--HVPPFSTSLMTPNTHTVITP
THPQMATSAYIHSTPTGTIPPP--------TTLKATGSTHTAPPMTPTTSGTS-QA----
-------SS----SFNTAKTS----TSLHSHNSSTHHPE----------------VTPTS
ITNITLNPTSIGTWTPVAH-----------------------------------------
-------------------------------------TTSATSSRLTTPFTTHSPPT---
--GS--SPISSTGPVTATSFHATT-TYPTPSHPHTTLPTHVPPSSTSLVTPNTHTLITPT
HAQMSTSASIHSMPTGTIPPPT-------------------------------TIK----
------------------------------------------------------------
----------------------ATGSTHTAPTMTPTTSGTSQA--LSSFSI---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------AKTSTSLHSH----TSSTHHPE-VTP
-TSTTNITTK----------HTSTATRTPVA-----------------------------
--------------------HTTSATSSRLPTPFTT--------------------HSPP
TGSSP--IS---STGPRTATSFQT---------TTTYPTPSHPQT-TLPTHVPPFSTSLV
TPS-TH-----TVITPTHAQMSTSASIHSTPTGTIPPPTTLKATGS--THTAPPITVTTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAPSSFSTAKTSTS--------LHSHTSSTHHPEVTPTST--TNITPKHTSTAT-
---RTPVAHT-------TSATSSRLPTPFTTHSPPTGSS--PISSTGPRTATSFQTTTTY
PTPSHPQATLPTHIPPFSTSLVTPSTQTVITPTHAQMSTSAYIHST--------------
--PTG--TI-PPPT---T-LKATGSTHTAPPMTVTT------------SGTS--QTHSSF
STTTASSSFISSSSWLPQNSSSRPPSSP-ITTQLPHLSSATTPVSTTNQLSSSFSPSPS-
--------APSS-----------V-------SYVPSSHSSPQTSSS---------SVGTF
SSF-----VSAPVHSTTLSSG------------------------------S-----HSS
L---------------------STH----PTT-----ASVSASPLFPSSPAAS-------
-TTIRATLPHTI-SSPFTLSAL-----------LPIS-------TLTVSPTPSSHLASS-
------------------------------------------------------------
T-IAF-PSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF--------VSLTSGVTG
IPT-----------------SPVTKLTT--------------------------------
---------RHPGPTSS-----------PTTRFLTSSLTAHGSTP-SSA-----------
-PVSSLGTPTPT---------S--------------------------PG----VCSVRE
QQEEITFK----GCMANVTVTRCEGACISAASFNIITQQ-VDTRCSCCRPLHSYEQQLEL
PCPDPSTPGQR--LVLTLQVFSHCVCSSVACGD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------

---------------------------------------------DKGSCSTWGAGHFST
FDNYLYDFFGTCNYIMATVCND-VTPDFNIQFRRGMNKKIERIIIEMGAVIVIVEKSIIV
IKGVGVIKLPYTSNGLQIAPFGRTV-RLVTKLMEMELIVVWNNDDYLMV-----------
---------------------------------MVERKYMRKTCGMCGNFDGQELNEFV S
E--GK---LLDAQQFAALQKMDDPSEICPSQEMAIPNIPRQ------------KYARICS
QLLNLVSPACNV--SKKAFVIRCQLDMQDCNDPGQRNCTCATLSEYSRQCSMSHQAVSDW
RSTDFC S-------VG----K CSANQIYKECGSSCVKTCSNPDYSCSSYCTYGCFCPEGT
VLDDISKNRTCVSINQ CPCTLNGERYDPGATMKATCR----TCKCRMGQWDCKDLPCPGR
CSLEGGSFVTTFDSRSYRFHGVCTYILMKSPSLPHNGTLMAVYDKSGYSHSETSLSAIIY
LSTKD--KIMISQNEL-LMDDELKHLPFSSGDITIFRQSSTHIQMYTTFGVELIAQLWPV
FHVYIKVGLLFKGRTL---GLCGNYNGDTTDDFMTS MDIIEGTAALFVDSWRA-GNCHPT
ADRDTDPCSMSQLNK MSAETHCSILTKKGTVFEKCHSVVNPAPFYK------RCVYQACN
YEETFPYICSTLGSYARVCASMGLILI----------NWRDAM-DN CT------------
----IS CTGNQTFSYHTEACDRTCLSLSNQALECYPTDIPIDGCNCPKGTYLNHRSECVR
KSM CPC-YLEDKRFILPDQS-TIIGGITCYCVNGNLSCTGRPQDP-AEN CKPPKKYVSCS
QRSDNKYGA---ACSPTCQMLATGIKCVPTKCESGCICADGLYENLDGMCVPPDK CPCEY
GGISYKKGEEIHTECKSC----TCTRGKWKCVQKSR---------CSST CTLYGEGHVTT
FDGQRFVFDGNC---EYT-------LATDGCGMNSSHSTFK----IVTENVICGKSGVTC
SRSIKIQLGNMTVILADETYSVYGE-NPLTQFHVKKNALHLMFDIIIPGKYNMTLIWNKH
MNVFIKIFRE-AQNHLCGLCGNYNGNMKDDFETRS KYVAANELEFVNSWKENPLCGDVL-
-FIVDPCSKNPYRK AWAQRKCSIINSQVF------APCHSKVYQAQYYEACVRDSCGCDT
GGDCECMCDAIAVYAKACLDVGVCIDWRTPDFCPVYCDFFNTHQKAGSEGTYSYNYWNEQ
NCTWHYRPCNCPNQNY--------------------------------------------
------------------------------------------------------------
--------------------------------KYVNIEGCYNCSHNEYFDHEEGQCKSCV
TKTVE-RTPPPRISKTTPTT--------PVSTTSRTTVST--------------------
-----------------------------------------ES---SPPSV---KIK--S
-------------------TSTPLSTTI-LSTS--STE--------------TI------
TTAT---TT--TPTTLTVTATTSS-TSSTE-----STTSKPT------------------
------------------------------------------------------------
----------------PTVSTTVTTPTTPTTLTTLTLTTTT--------LPTSTTEITTR
PTVS-----TTFTTSTSPTT--PTTHSLSTST--LPTSSTETTTSKS---T--PT-I-S-
TSFTTSTS-----------PTTPT--------------------------THS-L-----
----------------TT-S-T--L-P-A-S-------S-TE-T----------------
---TT-PKP-IP-T---VS-VTI-T--------TP-P-TT-----AT-PT-MS-------
-------------TTHSLT-----------------TST-LPTSS-TET-T-------TS
------KSTP-TISTSF----------TTS--TSP------------T-TPT-TH-SLTT
STLPA-SS-TETT-TP-KPI--------P-SDS-IT------------------------
----I-TTTPTTATPTM--------------STT--HSL-T-------------------
-TSTLPTSSTETTT---S--------------KSTP-------------T----VSTTIT
TPTTTT------TP-----TTLTTLTPTTTKPTTT-SMESSTSETT------------TP
STVKTTLTT---------------------------------------------------
--------------VSSTATS----TETTPT-----------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------SAHGLQGGMLSYQVVRW
VWSA--------------LDACPANQVYQECGAPCARTCSNPQHSCSGFCTFGCFCPEXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXX-XXXX--XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXLCGNFNGDTTDDFTTSVG MAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLN KVCAETHCSVLLKEGTVFETCHAVVNPKPFYK------RCVYKACN
YEETFPHICAGLGDYAHACASRGVLLR----------GWRSSV-DNCT------------
----IPCTGNRTFSYDSQACDRTCLSLSDREAECHRSAVPVDGCNCPEGTYLNHKAECVR
RSQCPC-LLEGHKPIPAEQS-AVFNGVICYCTNGRLSCPGQQQRL-LDSCPA-KTFQSCS
QSSENKFGA---A-CPTCQMLATGVTCVPTKCEPGCVCADGLYENANGQCVPPEECPCEF
AGVSYSGGAELHTDCSTXXXXXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXX
XXXXXXXXXXXX---XXX-------X--XXXXXXXXXXXXX----XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXDALCGLCGNYNGNMKDDFETRSK YVASDELEFVNSWKESPLCGDVS-
-FVVDPCSLNAFR RSWAERKCSIINSQTF------AACHTKVYHLPYYEACVRDTCGCDS
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPIYCDFYNTHARL-GSGDYQYTQ--EA
NCTWHYQPCLCPGRPQ-SLPDVNIEXXXXXXXXXXXXXXXXXXXXXX-------------
------------------------------------------------------------
---------------------------------------XX---XXXXXXXXXXXXXXXS
PP-TPAQP-TTVTLN---TTGL----------LSSPHTPVGSTGTPALPATSTAP-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------QPTASSGESPRTTAAITPWATSALAPTTTP-----------------RSTPIG
LTMTQATTQTTASSLSS-------------------------------------------
----STKSTAQSTSRTTEAQPTLATSETAPSS----------------------------
------------------------------------------------------------
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MLRVRQLL--LLLLFRGLLIDAGAWTGDVTN---SDTEDNLQSSPEKGWCSTWGTGHFST
FDGHEYNFQGMCNYIFTATCGDDMPATFSIQLRRDMDGTISRIIMELGASVVTVNKETIS
VRDIGVVSLPYTSNGLQITPYGQSV-QLVAKQLELELVITWGPDAHLT------------
--------------------------------VLVETKYMGKLCGLCGNFDGKIDNEFLS
E-DG K---LLEPHKYATLQKLDDPNEICAHEAIPSPIILK-----------T-RYAQICN
QLLTLVSPG CDI--PKETLMLSCQADMAACARPGQPNCSCATLSEYSRRCSMTGQPVRNW
RTPGL CP-------MS----Q CPANQVYQECGEVCVKTCSNPQHSCSSPCTFGCFCPHGT
LLDDISGNQSCVPVNQ CPCMLNGMVYGPGEITKTACQ----TCQCTMGHWTCTKQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPSEGTLMAVYDKSGYSHSETSLVAIMY
LSKKD--KIVISVDEVITNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLELVFQMQPV
FQVYITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GIDEGTASLFVDSWRA-GNCPAA
LEREMDPCSMSQLNKVCAET HCSMLLKKGSVFEKCHSAVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSARGILLW----------GWRNSV-DNCT------------
----VP CTGNRTFSYDSQACDRTCLSLSDRETECHVSPVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDDYKFVQADQS-TMINGVICHCINGRLSCPRQAEMF-FAS CPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIDCVPTKCESGCVCPKGLYENSDGQCVPAEE CPCDY
AGVSYPGGFELHTDCKTC----TCSQGRWTCQLSTQ---------CPST CVLYGEGHIIT
FDGQRFVFDGDC---EYT-------LATDDCGTNSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLFITMADSNYTVSGE-EPLVHLQVKPSPLNLVLDIDIPGRLNLTLVWNKH
MSVSIKIRRA-TQDALCGLCGNANGNMKDDFETRS KYVASNELEFVNSWKESPLCGDAS-
-YTVDPCSLNTFRRSWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDACGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDFYNTHTLV-GENEYQYAQ--ES
NCTWHYQPCLCPGSLG-SFPNTNT------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHSEGTCVPCA
PPTTTPPP-TTTGSQPTTET---TISTEFHSSTSA-NTPVAPSYLPGLPTP---------
-----------------PPSAPSFTE-------ELTVWTTPKESTVSSGE----------
-----------------------------YPQTT-MAA---------TPPTSPLP-----
----PTSIPKSTPTGLPVTQATSKPTASSL---SSSTKTTAE-LTESTTVT--------L
LT-LMPGMSTSQ----DKTS----------------------------------ASY---
------------------------------------------------------------
------------------------------------------------------------
----------------------------TTQDQSTSFHLTTISNWPTNGP----------
--QHFSH------------WKLLTFYPSITLQSGL---------LSLLATLASWDLQLT-
--------------------------GGRAPDCLPGLCG---------------------
----------------------------------KCDS--NSLPGFLRLLC-----QFQ-
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-------------------SPTGNATGPGAE---G-NLQS---SPDKGWCSTWGASHFST
FDYGAYDFSGTCNYVFAATCKNAMP-AFSVQLRRGPDGNIFRIIVELGASVITVENGTIS
IKDVGVVSLPYTSNGLQMTPYGQSV-QLAAKQLELELVVLWGPDPHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGNADNDFMS
E-DG K---LLEPHKFAALQKLDDPNEICTYEAIPSTPMLHA----------K--DAQTCA
QLLALVSP ECDV--PKKLLVHSCQVDMVACNPPGQPNCSCATLSEFSRRCSMAGQPVSRW
RGPGL CS-------LG----S CPASLEYQECGVVCTRTCSNPRHSCPSSCTFGCFCPEGT
VLDNLSTNHTCVPLSQ CPCMLNGVVYSPGEVTAATCQ----TCQCTTGHWTCMEKPCPGT
CSLEGGSFVTTFDTRPYRFHGTCTYILLQSPQLPDEGTLMAVYDKSGYSHSETSLTAVIY
MSQKD--KIVISEDEVITNHGDTKWLPYKTGNITIFRQTSTHLQMATTFGLELVVQLRPI
FQLYITVGSQFQGQTR---GLCGNFNGDTTDDFMTSM GIDEGTATPFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSELLRKGGAFEKCHTTVNPTPFYK------RCIYQACN
YEETFPHICAALGTYAQACASQGILLW----------GWRSSV-DNCT------------
----VP CTGNRTFSYNSQACGRTCLSLSDHEAECHPSAMPVDGCNCPEGTYLDHRGECVR
KAQ CPC-LLDSSKFLPSDQS-TMINGVICYCVNGRLSCSGQPQNL-LAS CPAPKTFQSCD
QSAEDKFGA---ACAPTCQMLATGTACVPTKCEPGCACAEGLYEDPNGECVPPEQ CPCDF
AGVSYPGGAKLHTDCKIC----TCSQGRWACQQGAH---------CPST CVLYGEGHMVT
FDGQRFMFDGNC---EYT-------LATDDCGTNSSQPIFK----VLTENIICGKLGVTC
SRAIKTTLGGLSITMADGSYVVHGE-DSHVHFQVQLSALSLVLDVDIPGRLNMTLIWNKH
MSVSIKISRS-SEDALCGLCGNANGNMKDDFETRSRYVASSELEFVNSWKESPLCGDMR-
-AAVEPCSLNAFRRSWAERKCSIINGQTF------AACHSK-------------------
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-------------------------------

-TMLGPWLL-LLLSCGDALLGAGEWGPVGG----------TLGKSPTGWCSTWGAGHFST
FDGHVYDFSGTCNYIFAATCEDASS-TFSVQLRRGPSGNISRVIVELGASVVTVQQGVIS
VKDEGVVSLPYTSHGLQMTPFGQSV-RLVAKRLELELVVVWGPGAYLMVRTLAGW-----
-------------GLLLALPRPSRRTVLPDPQVLVEKKNVGRMCGLCGNFNGQRTDEFLS
E-DG K---LLDPHKYAALQKLDDPNEICSYEAIPSPRGLQ-----------A-GHAQTCS
RLLTLVAP MCNV--SKEPFLLSCQADMAACAQPGWYNCSCATLSEYSRQCSMAGQPVRPW
RGPGL CS-------VG----E CPANQVYRECGEPCVRTCSNPQPSCSGFCTFGCFCPEGT
VLDDSSKNHSCVPVPQ CPCTRGGEVYAPGEATTAACQ----TCRCSGGRWECVEQPCPHR
CALEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPDGGALLAVYDKSGYSHSETSLAAVIY
MSSQD--KIVISRDEVITNNGDTKRLPYHTRNITVFRQTSTLIQMVSTFGLELEVQLSSV
FQVYVTVGPQFRGQTR---GLCGTFNGDTTDDFTTSM GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSHLNKVCAET HCAVLVKTGTVFEQCHATVDPKPFYK------RCVYQACN
YEETFPHICAALGSYALACASRGVLLQ----------GWRSSV-DNCT------------
----IS CTGNQTFSYNSQACDRTCLSLSDRKVECHPSAVPVDGCNCPEGTYLNHKAECVR
KAQ CPC-LLDDNKFLLAGQS-TAVNGVICHCINGRLSCPARPLML-LAT CSAPKTFQSCS
QNSEDKFGA---ACAPTCQMLATGTPCVPTKCEPGCACPRGLYENASGQCVPPEE CPCEY
GGVSYPRGAELHADCKSC----VCSRGTWTCQQSTR---------CPST CTLYGEGHVVT
FDGQRFVFDGSC---EYI-------LVTDGCGASDAQPTFK----ILTENVVCGNSGVTC
SRAIKILSGDLSIVLADGNYTVSGE-DPGVRFRVKAGSLHLELDATIGSAYNLSLIWNKH
MTVFIKVAGA-SQDTLCGLCGNYNGNMKDDFQTR SRYVASSELEFVNSWKESPLCGDTT-
-FTLDPCSLNTFRQSWAER KCSIINSQTF------AACHSQVYHLPYYEACVRDTCGCDT
GGDCECLCDAVAAYAKACVDKGVCIDWRSPDFCPIYCDFYNTHAQV-GGGEYQYTQ--EG
NCTWHYQPCLCPSWPQ-SLPGTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSRDEYFDPDKGTCVPCG
KPCPACCP-QPPAPKPTPLG---TPTPLTHTATATVTGTHTPSTTPSTPTL---------
-----------------PASTTSRVTAPPTGTPATTTTTHPTP---SHSQ----------
-----------------------------TPPV--TQS---------TPATASVT-----
----PTSRTVSAPTQSHPPSSTEKPTGTAT---------------PSTPV---------P
VTGTVPTPT---------------------------------------------------
--------------APPLT-T---------------T-----------------------
LTLTTNTQSPAS--------TTPIPT----------------------------------
----ATVP----------------PSPSPDHTGPTATPRTTSSPQPTTASTPTPLTH--T
ATATVTGTHTPSTTPSTPT----------LPASTT---------SRVTAPPTGTPAT---
-----------------------------TTTTHPTPSH---------------------
----------------------------------SQTPPVTQSTPA-TASV-----TPTS
RTV---------------SAPTQSHPPSSTEKP---------------------------
--TGTAT--------PSTPVP---------------------------------------
----VTGTVPTPTAPPLTTTLTLTTNTQSPASTTPIP-TATVPPSPSPDHTGPTATPRTT
SSPQPTTASTPTPL--THTATATVTGTHTPSTTPSTP---------TLPAS-TSSRVTAP
PTGTP--------------ATTTTTHPTPSHSQTPPVT--QS-TPATASVTPTSRTVSAP
TQSHPPSS--T-EKPTGTATPSTPV------PVTGTVPTPTAPPLTTTLTLTT-NT----
-------QS----PAST----TPIPTATVPPSPSPDHTG----------------PTATP
RTTSSPQPTTASTPTPLTH-----------------------------------------
-------------------------------------TATATVTGTHTPSTTPSTPT---
--LPASTTSRVTAPPTGTPATTTT-THPTPSHSQTPPVTQST-PATASVTPTSRTVSAPT
QSHPPSSTEKP-TGTATPSTPV-------------------------------PVT----
------------------------------------------------------------
----------------------GTVPTPTAPPLTTTLTLTTNT--QSPAS----------
---------TTPIP-------------------------------------T--------
------------------------------------------------------------
------------------------------------------------------------
--------ATVPPSPSPDHT----------------------------------------
-------------------------------------------------------G-PTA
-TPRTTSSPQ----------PTTASTPTPLT-----------------------------
--------------------HTATATVTGTHTPSTT--------------------PSTP
TLPASTTSR---VTAPPTGTPATT---------TTTHPTPSHSQT-PPVTQS-TPATASV
TPT-SR-----TVSAPTQSHPPSSTE---KPTGTATPSTPVPV-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------T--GTVPTPTAPPLTTT-----LT
--LTTNTQSPASTTPIPTA--------TVPPSPSPDHTGPTA-T-PRTTSSPQPTTAST-
---PTPLTHT-------ATATVTGTHTPSTTPSTPTLPASTTSRVTAPPTGTPATTTTTH
PTPSHSQTPPVTQSTPAT-ASVTPTSRTVSAPTQSHPPSSTEKPTGTATPSTPVPVTGTV
PTPTA--PP-LTTTLTLT-TNTQSPA-STTPIPTAT----------VPPSPS--PDHTAH
ATPRTT----SSPQPTT--AST--PTPL-THT--ATATVTGT---HTPSTTPSTPTLPAS
T-------------SSRVTAPPTGTPA-TTTTHPTPSH--SQTPPVTQSTPATASVTPT-
SRT-----VSAPTQSHPPSS-----------------------------TEK--------
-P---------------TGTATPST----PVPVTGTVPTPTAPPLTTTLTLTTNTHSTFS
TTSISTSLVSLS-ASS------------------PQS------STL--SPLP--SL-STP
L----STSH--------TVSPPL--SISSTLSPV-----------------------PAS
S-TVP-LSTPRTTASSPASPTASSRSTTSQSTSLTTRAP--------DLSLLSSTLRVTT
IPIS--P-----------------------------------------------------
---ATNFTTRRPSTTRW-----------LTTAFLSSSVTVQ-----PSSPVSHTG-----
HSISSLSTSLPS---------S--------------------------PG----TCSVKE
FEEEVTYQ----GCTANVTMTRCEGVCASSASFNTDTLQ-VDTRCGCCYPVSSYEQQLVL
PCADPGAQGQP--LTLTLQVFLRCECSPQHCSG---------------------------
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-------------------------------------------------CSTWGAGHFST
FDGHVYDFLGTCNYIFAATCKDTSP-TFSVQLRRGPGGGISRVIVELGASVVTVQKAVIS
VK---VVGLPYTSNGLQITPFGQNV-QLVAKQLELELVVMWGPGTHLM------------
--------------------------------VLVEKRHMGKLCGLCGDFNGEQTNEFLS
E-E GK---FLEPHTYAALQTLDDPDEICTYKAVPNPQVPQA------------EHAQTCT
QLLTLVAPECNV--PKEPFMWSCQVDMAECVLRGQHNCSCATLSEYSRQCSMAGQAVSNW
RGPGLC P-------VG----T CPANQVYQECGETCVKTCSNPQHTCSSFCTFGCFCPKGT
VLDDISRNHTCVPVTQ CP CMLNGVVYAPGEVVTAACQ----TCQCTTGHWKCTEQPCPQR
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPDGASLVASYDKSGYSHSETALAAIIYMSRED--KIVISQDEVFTHNGNTKWLPYKTRNITVFRQTSTHIQMTTTFGLELVIQLEPVFQAYITIGPQFRGQTR---GLCGTFNGDTTDDFMASTGIVEGTASLFVDSWRT-GNCPASLERETDPCSMSQLNKVCAETHCSVLVRNGSVFEKCHAMVNPRPFYK------RCVYQACNYEKTILHVCAALSDYARVCATRGILLR----------DWRNSV-DNCT----------------TPCTGNQTFGYDTRACGRTCLSLSDHAAECHPSAVPVDGCNCPEGTYLNHKAQCVRKSQCPC-LLDSNKFILADQS-AMVNGVICYCINGRLSCPGRPQML-LATCSAPKTFQSCNESSENTFGA---ACAPTCQMLATGTPCVPTRCEPGCVCAEGLYENANGQCVPPEECPCEFAGASYPPGAELHTDCRTC----TCSRGKWTCWQSAR--------C-SSTCALYGEGHVVTFDGQRFMFDGSC---GYILTT-------DGCGANNSRPTFT----VLTENVVCGKSGVTCSRSIKISLGGLSIVLADRNYTVSGE-DPHVHFRVNAGSLNLVLDITISNRYNLTLVWNKHMTIFIKITRA-TQDALCGLCGNYNGNMKDDFETRSNYVASSELEFVNSWKDSPLCGDTS--LALDPCSLNTFRRAWAERKCGIINSPTF------AACHSQVYHLPYYEACVQDACGCDTTGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDYYNTHTH--EDGAYQYNQ--DANCTWHYQPC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPDGASLVASYDKSGYSHSETALAAIIY
MSRED--KIVISQDEVFTHNGNTKWLPYKTRNITVFRQTSTHIQMTTTFGLELVIQLEPV
FQAYITIGPQFRGQTR---GLCGTFNGDTTDDFMAST GIVEGTASLFVDSWRT-GNCPAS
LERETDPCSMSQLNKVC AETHCSVLVRNGSVFEKCHAMVNPRPFYK------RCVYQACN
YEKTILHVCAALSDYARVCATRGILLR----------DWRNSV-DN CT------------
----TP CTGNQTFGYDTRACGRTCLSLSDHAAECHPSAVPVDGCNCPEGTYLNHKAQCVR
KSQ CPC-LLDSNKFILADQS-AMVNGVICYCINGRLSCPGRPQML-LAT CSAPKTFQSCN
ESSENTFGA---ACAPTCQMLATGTPCVPTRCEPGCVCAEGLYENANGQCVPPEE CPCEF
AGASYPPGAELHTDCRTC----TCSRGKWTCWQSAR--------C-SST CALYGEGHVVT
FDGQRFMFDGSC---GYILTT-------DGCGANNSRPTFT----VLTENVVCGKSGVTC
SRSIKISLGGLSIVLADRNYTVSGE-DPHVHFRVNAGSLNLVLDITISNRYNLTLVWNKH
MTIFIKITRA-TQDALCGLCGNYNGNMKDDFETRS NYVASSELEFVNSWKDSPLCGDTS-
-LALDPCSLNTFRR AWAERKCGIINSPTF------AACHSQVYHLPYYEACVQDACGCDT
TGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDYYNTHTH--EDGAYQYNQ--DA
NCTWHYQPC---------------------------------------------------
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-------------------------------

--MLRRWL----LCFCGALLGAGLPD-AYASPGPQRPKDSPQTAPDKGHCSTWGVGHFST
FDHHVYDFSGTCNYVFAATCKDAFP-TFSVQLRRGPDGGIARIIVELGASVVTVSDGTIS
VKDVGIVSPPYTSNGLQITPFGQSV-RLVAKQLELELEVTWGPDAHLTV-----------
---------------------------------LVEQKYMGQMCGLCGNFDGKATNEFIS
E-EAG---SSPSHGHP------------------------------------ANHMQGCL
AHWDLRAPERRWGLSWAPGTGTCLCLLGAATHWEPRLGTQCLAQRRKGKCSWSETPQTGW
GAS---------------------------PG--------------ARESGRPSPSPAGT
VLNDLSNNHTCVPVTQCPCVLNGATYAPGAVTTAACR----TCQCTLGRWVCTERPCPGH
CSLEGSSFVTTFDARPYRFHGTCTYILLQSPQLPEDGTLMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVSNNGAAKWLPYRTRNITVFRQTSTHLQMVTSFGLELMVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTS LGIPEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-ENCT------------
----VP CTGNSTFSYDSRACERTCLSLSDRAAECHTSAVPVDGCNCPDGTYLNHKGECVH
KAQ CPC-TLEGYKFILAQQA-TMINGATCYCTNGRLSCPQRPQMF-LAS CPTPKTFESCS
QSSENEFGA---ACAPTCQMLATGVACVPTKCEPGCVCAKGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQATH---------CPAT CTLYGEGHIVT
FDGQRFVFDGSC---EYI-------LATDGCGANDSQPTFK----ILTENVVCGKAGVTC
SRAIKLFLGGLSVVLADRNYTISGE-EPHVQLRVRPDALSLAVDVGVPGRYNLTLVWNRH
MSILIRIARA-SQDAICGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSVINSQTF------ATCHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNSHAQD-GHGQYQFTE--EA
NCTWHYQPCLCPGQPQ-SVPGSNV------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGACMPCA
PPSTPQPP-TT---AGLPHSGSRPTQVWPTTGTA---TTIRLLSST-GPSL---------
------------------------------------------------------------
-----------------------------SSKST-TA----------GPTQTPL------
---------------LPATLTPSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPLRPTTAVTPQATSGQTPTATL-----------------RSTATK
PTVTQSTTQAT------ASTISPA------------------------------------
-----TKSTAQSTTRTTA------------------------------------------
------------------------------------------------------------
-----------------------------------TPAT-----SGTSPTLA--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-HQELPGTMATPTTGP--RP---------------------------
----------------------------TAASTTGPTTPRPEQPT-------------R-
----PTA--TEKTT--HTR-TTEDTTPQTSHTTHSTA---------M--GG-SPASSTGP
TITAS--------------FKTTATHPTPPHPQTTLPT--HVPTFSTSSVTPSTQKIITP
THPPISTSPSIHSTPTGTVPVP--------TTVQVTGTTHTAPPIIATTTGTS-QA----
-------HS----SFSTATTS----TSLHSQASSTHYPE----------------TTPPP
TTTSTPKPTGTGTSTPVAH-----------------------------------------
-------------------------------------STSATISRPPTPFTTQSPPT---
--GS--RPVSSTGPMIATSFKTTT-THSTPPHPQTTRSTHVPPFSTSSVTPRTHTFITPT
HPPMSTSPSTHSIPTGTVPPQT-------------------------------SVR----
------------------------------------------------------------
----------------------ATGSTHTAPPMTATTSGTSHTHS--SF--TTISTSLHS
QASSTHRPETTPTS-------------------------------------STTITPKTT
SRG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------TAPPITPTTSGTSHAH----SSFSTATTSTSLHSQ----ASSTHRPE-TTP
-TSSTTITPK----------TTSRGTGTPVA-----------------------------
--------------------TTTLTTSSRSPTPFTT--------------------HSPP
TGSRP--IS---STRPMTATSFKT---------TTTHPTPSHPQT-TLSTHVPPFSTSSV
TPS-PH-----TVITPTHPQVSTSPSIHSTLTGTIPVSTTVKATV--STHTAPPMTATTR
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAQSSFSTPTTSTS--------FHSHASSTHRPETTPTSS--TTVTPKTTSRGT-
---STPVATT-------TSAAGSRPPTPFTTPTPPTGSR--PVSS---------------
--------------------TVTPSTHTVITPTHPPTSTFPSIHST--------------
--PTG--TV-VPQT---T-VRATGSTHTAPPMTATT------------SGTS--HTHSSF
STTTSSTSFMSSSSPQ--NSSSRPPSS-SATTPLPHSSSPTTPVSATHQLHSSASSPPPS
AP-----SS--------------------VTPHVSSAHSSPQT---------------SS
SSA-----VSVPVHSTTLSSGS-------HSFFT-RS-----------------------
-----------------------------------PAASVSGSPFSP---------SPAA
STTSRASLPHTT-SPTVGLSTL-----------LPIS-------TPTA------------
-----------------------------------------------S-----------S
T-TAF-LSTRRTTASTHLASAISSQSTTSRSTSLTTRVPTPGF--------VSLTSGVTG
IPSSPIT-----------------------------------------------------
-----NLTTRHPSPTSL-----------HTTWFPTSSLTAHGSTP-ASA-----------
-PVSPLVTTTPS---------S--------------------------SR----VCSVQK
QQEEITFK----GCVANVTVTRCEGVCTSSASFNIDTQQ-LDARCSCCRPLRSHEQQLEL
PCPDPSAPGQQ--LVLTLQVFSRCVCSSVSCGH---------------------------
------------------------------------------------------------
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-------------------------------

MLG--PWL---LLLCGAALLGAGLDTSSANHSGL-RWRNPAQTAGATGWCSTWGAGHFST
FDGLVYDFSGTCNYVFAATCEGTSP-AFSVQLRRAPGGAISRVIVELGSSVITVEKEAVS
IKDVGPVSLPFTSNGLRILPFGQNM-RLVAKQLELELTVTWHGGDYLM------------
--------------------------------VMVERKFMGKMCGLCGRFDGEKLNEFLS
D-D GE---LLEPHKYAALQKLDDPSEICAYEEIPSPRSLQW------------EHAQACS
RLLALVAPACTV--PKEPFVRSCQVDMAACTRAGQHNCSCATLSEFSRQCSQAGQAVSNW
RGPGLC A-------VG----P CPATHVYRECGAACVRTCSNLQHSCPGVCTSGCFCPEGL
VLDDLSGNHTCVPVAQ CPCLLNGAVYGPGQVTAAACR----TCRCSMGRWACTERPCPGR
CALEGGSFVTTFDARPYRFHGTCTYILLQSPRLPDEGTLMAVYGQSGYSHSETSLTAIVY
TTSQD--KLVISQDGSVTNNGDTKWLPYKTRNVTVFRQTSTHLQVVTPFGLEVVVRLWPV
FEVYLTVEPQFRGQTT---GLCGNYNGDTTDDFTTSM GIAEGTASLFVDSWRA-GNCPPA
LERETDPCSMSQLNKLC AETHCAALVRKGTVFEKCHVAVNPTPFYK------RCVYQACN
YEDTFAHICAALGDYAHVCASRGVLLW----------GWRGSV-DN CT------------
----TP CTGNQTFSYDSHACGRTCLSLSDRSLECHPSSVPLDGCTCPKGTYLNHKSECVP
KAQ CPC-HLDAHTFVLPGQS-TALNGITCHCSNGRLRCAGPPQML-MVSCVPPKTFRSCS
QSSEDKF GA---ACAPTCQMLATGSTCVPTKCEPGCACAKGLYENATGHCVPPDD CPCEF
AGVSYPRGAELHTDCKNC----TCSRGKWACQQSTH--------C-SST CTLYGEGHVLT
FDGQRFMFDGNC---EYLLAT-------NDCGTGDPRPTFK----ILTENVICGRSGVTC
SRAIKIFAGALSIVLADRTYSVSGE-DPQLGVQVRPSALNIELDLDIPGKLQLQLTWNKH
MTVYIRATRL-SQDALCGLCGNYNANMKDDFET RARYLAADELEFVNSWKENPLCGDVS-
-FVADPCSTNAFRR AWAERKCAIINSPTF------ALTPPQVYHLPYYEACVHDTCGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPIYCEFYNTHTQASGDSEYQYTP--EA
NCTWHYQPCLCPGHLQ-SLPTSNVEG----------------------------------
------------------------------------------------------------
---------------------------------------CYNCSQDEYFDYAAQACVPCA
LLTSTPRP-PLSTGAP-----------------------------STVTRST--------
----------------TPYPGTSGHASST-------------------------------
---------------------AATPGGTT-------------------------------
----------------------------------------------------ATASAPAP
SSTH------------------------------------------------------TE
AASGPSTKPTGPSGEPPASTTAVTPWTTLG--PTATL-----------------GSTATR
PTVTQATTRPPGSHP------TTV------------------------------------
-----TRSTAKSTSRTSAGTPSATTPEVHT---------STGTLQPATASTTPEGSTSTP
EENTGPTR----PLPSQAST--------TDHGSSTPQP-----------T----ENTSK-
------ETH----KNTQIQGV------------SH---------------LMAPNI--SQ
-STGPPP-----------------------------------------------------
------------LTTTISGPT-------LSRPETTTH--------ASRPPPLASTSAV--
--TPTSRRTLPP---SHGQTLSSTGTHGPTAS--A-HSSPGVPPTGTGPTPS-TLP----
---------RT----LST---SVSGPPHSPGSTLRTSTSPAPQPP-------STPRPESP
SAPHTTTTGTGTLPAHTS--SATPSGTNTPASTSSTP---------TIPVS-TTAHGTGP
TAGTS-------------PLTTTISGPTPSRPETTTHASGPPPSASTSAVTPTSPRTLPP
SHGQTLSSTGTHGPTASAHSSA-------GVPPTGTGPAPTTS------------APRTP
TGGPSQPHS----TLSTARTS----SSPATAPSAT----------------------PQH
GSTTSRSPPASGPATPTPGAATTAATS---------------------------------
------------------------------------------------------------
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-------------------------------------------------CSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEAVWGPDSHLM------------
--------------------------------VLVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTFEDIPNTHVRQV------------QHAQICT
QLLTLVAPECSV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGLC S-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAACQ----TCQCTQGRWVCRERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPVA
LERETDPCSMSQLNKVC AETHCSVLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACTSRGVLLW----------GWRSSV-DN CT------------
----IP CTGNTTFSYNSQACERTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIINGITCYCINGRLSCPQRPQMF-LAT CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQGTH--------C-PST CTLYGEGHIVT
FDGQRFVFDGNC---EYILAT-------DGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDMR-
-FVADPCSLNAFRR SWAERKCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-GHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SVPGSNIEGAR------------FMHIHSRIFI----------
---------------HARTFVHPLTHIHT---HSLMPVPGQGTWPYTKQTV---------
---------------------LHPGASL---PARERCLSCYNCSQDEYFDHEEGVCVPCK
TQAASSPW-QQREKNSTE-------PRWALPSLFH--QPPAP---PTLTRPA---RVP--
-GVESGN---HTVPATTPQPSTTGDCTHT--RCQGLTWQLELGEELSP-QPGSSLVPVAL
--AGSTDEHTVGPQQVTAAMQKARPGARLHSESHGPALKAKQAVGRVLPKDVPVPCSPDG
MSVHPGSR----PTQVWPTTG------------------------TSTTIGLLSSTGPSP
SSKHTPASPTQT------P---------------------------------------LL
PATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRATASTA------SPA------------------------------------
-----TTSTAQSTTRTTVTPPTPATPGTSPTLRPE---TETGTIPPQTT-----------
-------------VKSTRS---THTAPPMTTTTITPTS-----TTTITPKSTSTSTGTP-
------VTH----------------TNSATSSRTPIPITTHSPPTGTGTPVAHTTL--VT
-SSKPPP-----------------------------------------------------
------------PFTTYSPPTTTTTYPTPPHPQTTF----------PTHIPPFSTSLV--
--TPTTHTVITP---THVHLST--------------SASIHSMPTGTIPPPT-ALT----
---------TT----GS----------------------MHTAPSMTVTTK-ITPTSTTA
ITPHPTSTDTGTPVAHTT--SATSSRPPPPFTTHSTP---------TGS---SPTTSKGP
TTTTS--------------LKTTTTYPTPSHPQTTIPT--HIPSFSTSLVNPSTHPVIIP
THAQMSTFTYMHSMPTG-TIPP-------QTTVKATGSTHTAPPMTATTNHHYLSNPITP
SDHTSHSCSTFLHLLGDSKHS----HSHNPYPRTDVHFCLHPLNVHRHHCTTDNKITPTS
TTTNNPKPTSTGTGTPVTRTTSVTSSRPPTPFTTHSPP----------------------
---------------------TGSTPITSTTTTT-----YPTPSHPQTTLPTQVPPSSTS
SVTPRSRPSSSTGPMTTISFKTTT-TYPAPSHPHTTLPTHVPPFSTSSVSSSTHDVITPT
HAQMSTSTSIHTTKTSTPLYSHTSSTHHPEITPTSTTTITPNPTSTGTGTPVADTTSATS
NRPPPPFTTHSPPTG-STPITSTGPITVT--------SF---------KTTTTYPTPSHP
QTSLPTQVPPFSTSSVTPVITPTHTQTHTAPPMTATTSVTSQA--HSSFSTTKTSTPLYS
HTSSTHHPEITPTS-------------------------------------TTTNTPKST
STGTSTTVTHATS-ATSSRTLTPITTHS-----SPTGSSTLSSTGPMTATSFQTTTIYPT
PSHPQTTLPTHVPPFSTSSVTPGSIPISSTGPVTTTLKTTTTYLTTSHPQTTLPTHIPPS
STSLVSPSTHTVITPTHAQVSTT----------------------TFIHPSPTGTIPPLT
TFRTTGSTHKTPPRTVTISGTSQAH----SSFSTAKTSTSLHSH----PSSTHQP-EITP
-TSTTTITPK----------QTSTGTGTPVA-----------------------------
--------------------NITWATSSKLPTGF-T----------THSPPTGSSH----
-ISSTGPLT---------ATSFQT---------TTTYPTPSQPHT-TLPTHIPPFSTSSV
TPS-TH-----TVITPTHAQVSTSAYIHSTPTGTIPPPTTVKATGTVSTHTAPPMTATTS
GTSQTPSSFSTAKTSTSRHTHASSTLHTEVTP-TFTTITPNP--TSRITGTPVAHTTSAT
SSEPPTPFTTHSPATG----SNPLSSTGPMTATSFKTTTTYPTTSQPQSTLSTHVPPLST
SLVTPTTHTVISPTNTQMSTSSSIHSVPIGTIPSPTTVKVTGSTHTAPPTTANTSGT---
--SQA--HSSFSTAKTSTS--------LHTHTSSTHHPQVTPTS---TTITLNPTSTGT-
---STPVAH-------TTSATSSKPPTPFTTHSPPTGSI--PISSTGPITATSFQTTTTY
PTPSHPQTTLPTHIPPFSTSLVTPTTHTVITPTHAQHPEVT-------------------
--PTS--T----------------------------------------------------
-----------------------------TITPKPTSTGTGTPVAHTTLATSSRLPTTFT
TH-----SPPTESTPISSTGPMTATSFKITTTYPNPSH--PQTTLPTHVPPFSSSLVTPT
THT-----VITPTHAQRSTSISI-----------------------------------HS
-------------------TPTGTIPP--PTTVKATGSTHTALPMTVTTSGTSQAPSTFS
TTKTSTSLHSHT--SSTHHPEV-----------TPTS--------TTITPNLTSTGTSTP
VAHTTSATSSKLPTTFTTHSPPTESSPVSSTGPITATSFQ-TTT-----T----------
---YPTPSHPQTTLPTHIPPFSTSLVTPT---THTVITPTH--------AQMSTSTSIHS
VPIGTIPPPTTVKVTGSTHTAPPTTANTSGTSQALSSFSTAKTSTSLHSHTSSTQHPEVT
PTSTT----ITPNPTSTGTGTPVAHTTSATSSKPPTPFTTHSPPTG-SIPISSTGPITAT
SFQTTTTYPTPS---------HP---QTTVPTHIPPFSTSLVTPTTRPTGTIPPVTTVTP
TSTTITPKPTSTGTGTPVAHTTLATSSRLPTTFTTHSPPTESTPISSTGPMTATSFKITT
TYPTPSHPQTT--LPTHVPPVSTSLVTPTTHTVITPTHAQRSTSTSIHSTPTGTIPPPTT
VKATGSTHTALPMTVTTITPTS------TTITPNSTITGTSTPVAH-TTSATS-SRLPTS
LTTHSPPTESTPDSSTGP---MTATSFQTTTTY-----PTPSHPQTTLPTHVPPFFTSLV
TPTTHTVITPTHAQMSTSTSIHSTPTGTIPPPTTVSATGSTHTSPQITVTTTKTSTPLHS
HTTSTHHPQVTPTSTTITPNPTTTGTGTPVAHTTSATSSRLPTPFTTHSPPTESSPVSST
SPITATSFQ--------------TTTTYPTPSHPQTTLPTHVPLFSTSLVTPTTHTVITP
THAQHPEVTPTSTTITPNPTTTGTSTPVAHTTSATSSRLPTTFTTHSPPTESSPVSSTGP
MTATFFQTTTTYPTSSHPQTTLPTHIPPFSTSLVTPTTHTVITSTHAQMSTST----SIH
SVPIGTIPPPTTV-TLTSTI---------IVPNPTSTGTGTPVAHTTSVTSSEPPT---P
FTTHSPATGSTPVSSTGTMTATSFKTTITYPTPSHPQTTLPTHVPPFSTSLVTPTTHIAI
TPTHTQMSTSTSIHST-----PTGTIPPPT---TVKATGSTHTAPPMTATT---------
--------------ITPTSTTITPNSTSTG----TSTPVAHTTSATSGRLPTTFTTHS-P
PTESSPISSTGPMTATFFQTTTTYPTSSHPQTTLPTHGPSFSTSLVTPTTHTVITPTHVQ
MSTSSSIHTAKTSTPLHSHTSSTHHPEVTPTSTTTITPNPT-STGTGTPVAHTTSATSSR
LPTIFTTHSPPTGSSPVSSTGPMTATSFQ--------------TTTTYPTPSHPQTTLST
HVPPFSTSLVT---------PTTHTVITLTHAQMSTSTSIHSTPTGTIP-----PPTTVT
PTSITITPKPTTTGTSTPVAHTTSATSSKLPT-TFTTHSPPTESSPVSSTGPITATSFKI
TTTYPTPSHPQTTLPTHVPPFSTSLVTPTTHTVITPTQTQMSTSASIHSMPTGTISPPTT
VTPTSTTITPNPTTTGTGTPVAHTTLATSSRLPTTFTTHSPPTESSPVSSTGTISPPTTV
KATGSTHTAPPMTVTTSGTSQAHSSFSTTTASYSFISSSSWQPPNSSSRPPSPPSATTQL
PHLSSATTPVSTTNQLSSSFSPTPSAQSSVS

LLR--LLL---LLSNGGALLSTGLDNTFFARPGLWKSEDSPQIDPDKGWCSTWGTGHFST
FDHHVYDFLGTCNYVFTATCKDASP-TFSVQLRRGLDGNISRIIMELGASVITVSKATIS
VKDIGVISLPHTSNGLQITPFGQSV-RLVAKQLELELEVLWSPDAHLT------------
--------------------------------VLVERKYMGRMCGLCGNFDGKTANEFLS
E-E GK---LLEPHKYAALQKLDDPNEICAYEAVPRPPVWQT------------KHAQICT
QLLALVSPECNV--PKSPFVLSCQADMATATQPGQQDSKCATLSEYSRQCSMAGQPVRSW
RRPGLC A-------VG----P CPAGQVYQECGSACVRTCSNPQHHCSSFCTFGCFCPEGT
VLNDLSTNHTCVPVTQ CPCVLNGAIYAPGDITTTACR----TCQCTSARWTCTEHPCPGH
CSLEGGSFVTTFDARPYRFHGSCTYILLQSPQLPDEGTLMAVYDKSGYSHSETSLAAVIY
LSKQV--KIVISQDGVITNNEDPKWLPYQIRNITVFRQTSTHLQMATTFGLELVIQLQPI
FQVYVTVGSKFRGHTR---GLCGNFNGDTTDDFMTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVC AETHCSVLLRKGTVFERCHATVNPAPFYK------RCVYEACN
YEETFPHICATLGSYAHACSSQGILLW----------GWRSSV-DN CT------------
----IP CSGNRTFSYDSRACGRTCLSLSDRAVECQPSAVPVDGCNCPEGTYLNHRGECVR
RAQ CPC-VLEGGRLIPAGQS-TVIDSVACHCTGGRLSCPGRPQMF-FASCSAL KTFQSCS
QSSENKFGA---ACAPTCQLLATGTPCVPTKCEPGCVCAEGLYENASGQCVPPEE CPCEF
AGTSYPGGAKLHTDCRTC----TCSRGKWTCQQSLH--------C-PST CALYGEGHVVT
FDGQRFVFDGNC---EYILAT-------DGCGTNDSQPTFK----ILTENVICGRSGVTC
SRAIKIFSGGLSIVLADSNYTVTGE-DPRVHLRVKPSSLNLILDISIPGRYSLTLIWNKH
MTIFIKIDRA-SQDPLCGLCGNYNGNMKDDFETRS KYVAANELEFVNSWKESPLCGDVS-
-FLAEPCSLNAFRR SWAERKCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDT
GGDCECLCDTVAAYAKACLDKGVCVDWRTPAFCPIYCDFYNTHTQVGGSGELQHTQ--EA
NCTWHYQPCLCPGQPE-SLLDTNIEG----------------------------------
------------------------------------------------------------
---------------------------------------CYNCSQDEYFDHKRGSCVPCV
PPTTPWPP-TTGHMPH----------------------PGSP---PTEVQPT---T----
------------------------------------------------------------
------------------------------------------------------------
--------------------V------------------------THSTIGHRSTPEPWP
SPTQTPQLLTTR------PS--------------------------------------GL
S--TKSTVSSSSMEESPRTTTVVTPRTTV-------P-----------------APTATR
PTMTQANTQPTASSL------SPA------------------------------------
-----TKLTAQSTVWTTVPPETSAVSGTSPRIAES---TNQASTGPTANQTPD-------
--NTGPAT----TSKTTRGITT------------HPGQ------------TSPPETWTQ-
------TSQTLT------------TS---TATTSPHPHTTHTPSTGSLPSTTH-------
--TRGPP-----------------------------------------------------
------------TEMSF---KTTSITPSAPNHHTTL----------PAHVPSSSTSLV--
--TQTAHQGSTT---THSEIPT--------------TSMPKSTPTR--RPTT-TVK----
---------ET----GSTSPFTVTNQPMSPFTTAKTSSSQHSQTASTSHHQ-PTASNATT
ITPRLTTSDTGPTMV--KSTTSANNRPHTPLMTNSPS---------TGSLP-HTPHTTRP
PSGTS--------------FKTSSTAPTPTRPHTILST--YIPSSSTSLVTQTAHQGSTP
THSEIPTSNSTLTSTS--TRLP-------ITTLKATGS---TSPFTTTSLS---------
-------SSP----FSTAKTS----SQHSQTASTSHHQ---------PTTSTATTITPNF
T--TSATGPATGSTSPF-----TGTSQPQSPFTTAKTSSSQHSQTA-----STSHHQSTA
TYATTITAELTTITPKLTTSDNGPTMLQ---------STTPTNSLPHTPHTTHSPST---
--GSLPSIPHTTGPPFGTSFKTTSSTVLTPPHPHTTLSTHVPSSSTSLVTQTAHLGSTTT
HSEIPTSNSTLTS--------------IPTRLPITT--L----KATGSTAP---LTG--T
SQPQSPFTTAKISSS-Q-------------HS--------------------QTASTSH-
-----------------------------------------------------------H
QTTATHATTITPKL-------------------------------------T-TITPKLT
TSDNGPTMFQSTT-LTNSLPHTPHTTHS---PSTGALPSTPHTTGPPSGTSFKTTSTAPT
PPHPHTTLPTHVPSSSTSLVTQTAHQASTQTHHS-EISTSTS--RPTATATRLPTTTPRA
-TVSTSPF---------TMTSQGISPFTTDKT-----------SSSLISLSS--------
-PSLTQNSSSTPPFSLSVTPHSPNPSSVTTIFSPTN-------------SLLPSP-HLPS
TTSPSSLSPSS-----------ASAHGSSSQ-----------------------------
--------------------ASTWTSSIHSFTSLTASSTPVHSFTLSSGSPTPFSTLPLT
TVMSTSAFPSFTLPHS--TLSFTP------SAQSSTPPLPLFPTESHLPAHSTSVSSSTL
RTT-AH-----TPTPAISSQATTRHFTA-F-TTQVPH---------------PSSLSSTS
GLTATPSSPATSF--TTR--HPDNTL---LPTSIFPSSSFSPH--------GSTAASAAS
--SSSLVTTPPYSTPGACSVREW------QEEITFKGCTANVTMTRCEGACAS-----ST
------SFNIDTQQVDTHC----GCCHPLSF---------YEQQLELPCSDSSVPGQRLM
LTLQVFNSCACSP--------------RGCRA----------------------------
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MLRVGHLL--LLLLFRGPLINAGARTGDATD---SDSEDNLQSSPEKGWCSMWGAGHFST
FDGHQYNFKGMCNYVFTATCGDDLPTTFSIQLRRDGDGNISRIIIELGASVVTVNKETIS
VRDIGVVSLPYTSNGLQITPYGQSV-QLVAKQLELELVIMWGPDAHLMV RFTGGEVGVPG
TLE--SKGSPAGVGNSLCIPT---GTNGITP QVLVEKKYMGKLCGLCGNFDGKIDNEFLS
E-DG K---LLEPHKYATLQKLDDPNEICAHEAIPSPSILK-----------T-RYAHICN
QLLTLVSPG CDV--PKETLMLSCQEDMADCAQPGQPNCSCATLSEYSRRCSMAGQPVRNW
RTPSL CP-------MS----Q CPANQVYQECGEVCVKTCSNPQHSCSSFCTFGCFCPHGT
LLDDISGNHSCVPVNQ CPCMLNGMVYGPGEITRTACQ----TCQCTMGHWTCTKQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPNEGTLMAVYDKSGYSHSETSLESIIY
LSKKD--KIVISEDEVITNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLQIMFQMQPV
FQAYITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GIDEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLKKGSVFEKCHNVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSSRGVLLW----------GWRNSV-DNCT------------
----VPCSGNRTFSYDSKACDRTCLSLSDRETECHASPVPVDGCNCPEGTYLNHKAECVH
KTQCPC-LLDSHKFVQADQS-TMINGVICYCINGRLSCPRQAEMF-FASCPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGTACVPTKCESGCVCPKGLYENSDGQCVPAEE CPCDY
AGTSYPGGSELHTDCKTC----TCSQGRWTCQLSTQ---------CPST CVLYGEGHIIT
FDGQRFVFDGNC---EYT-------LATDDCGANSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLSITMADGNYTVSGE-EPLVHLQVKPSPLNLVLDIDIPGRLNLTLMWNKH
MSVSMKIRRE-TQDPLCGLCGNSNGNMKDDFETRS KYVASNELEFVNSWKESPLCGDAS-
-YAVDPCSLNTFRRSWAER KCNIINSQTF------AACHSKVYHLPYYEACVHDACGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDFYNTHTLV-GDNGYQIAQ---H
NCTWHYQPCLCPGSLG-SFPDTNT------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHKEGTCVPCG
KSSRRSHM-LYTGSQPTTAT---PISTEFHSSSST-STPVGPSYLPGLPTP---------
-----------------PPSAPSSTE-------EGTDWTTPKKSTVSSGE----------
-----------------------------YPQTT-VAT---------RPLTSPLS-----
----PTSIPKSTPTRPTVTEATSKPTASSL---SSSTKTTAE-FTESTTVT--------L
LTSVMTGMSTSQ----AVTP----------------------------------TTEILN
TPTGQHSVSPAASSTPPRT-VL-PTTLEGTRPPHTTVPV---------------IYTTSA
TTSTKGSLST-----------HRTST----------------------------------
----AHLS----------------ESSAMTPTQSTSILATTNSLKPTTGV----------
--TATSVVHTSSGTPSSAPTPHTTLSPPTAVFSST---------THSTAPHVRTSEP---
-----------------------------STTTLPTPSA---------------------
----------------------------------PQTSSVTSLPSLSPSSV-----SPTS
EVH---------------I-----------------------------------------
------------------------------------------------------------
--------------------------------------------------TPTSPLPATS
NSIKPTVSSTGTPV--IHTTSATTSGPQTPRTTHPSP---------TEAVS-STVQTTGL
PSGTS--------------MQTATNLPTHSGPQTSAST--QPPLISTSAVTPTTEILNTP
TGQHSVSPAAT-STPPRTVLPT---------TLEGTRPPHTTVPVIYTTSATT-ST----
-------KG----SLSTHRTS----TAHLSESSAMTPTQ----------------STSIL
ATTNSLKPTTGVTATSVVH-----------------------------------------
-------------------------------------TSSGTPSSAPTPHTTLSPPT---
--AVFSSTTHSTAPHVRTSEPSTT-TLPTPSAPQTSSVTSLPSLSPSSVSPTSEVHITPT
SPHSHTVSSVSMSGPVSTILQT-------------------------------TIE----
------------------------------------------------------------
----------------------QTRPPNTPTAATSSTSATTQT--QSSFSTERTSTSHLS
QTSSNTVHPSTAGP-------------------------------------TTTATKS-T
MGGTATPVVHTTS-GASTTPQAGSSTHL---PTTAAVSSTKHTTGVSLETSVQTNTASPT
PSALQTSLATTPPSFSTSAV----------------------------------------
-----TQTSEVIVTPTPQHTIS-----------------------SASTSTARATILPT-
TLEQTRPPHTSAPVIYTTGAITQTK----T-FSTGRTSPS--TSHPSETASVTAHG-STS
-MPATSNSIK----------PTVSSTGTPVI-----------------------------
--------------------HTTSATTSGPQTPRTT--------------------HPSP
TEAVSSTVQ---TTGLPSGTSMQT---------ATNLPTHSGPQT-SASTQPPLISTSAV
TPT-TE-----ILNTPTSQHSVSPAA---TS---TPPRTVLPT-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------NGHTAPSPSSFIPLSTI-----LT
--TPTVT-----------------------------------------------------
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----MYDFAGTCNYIFAAICKDASA-TFSIQLRRGPSGNISRIIVEMGASVVTVQKAVIS
IKDVGVVSLPYTSNGLQITPFGQSV-RLVAKQLELELVVMWGPGAYLMV-----------
---------------------------------LVEKKYMGRMCGLCGNFDGEKTNEFVS
E-N GK---LLEPHKYAALQKLDDPNEICAYEAIPHPQVLQ-----------A -KHAQTCS
QLLTLVSSECNV--PKEPFVLSCQADMATCAQPGQQNCSCATLSEYSRQCSMAGQPVNSW
RGPGLC S-------VG----Q CPANQVYQECGEACVKTCSNPQHSCSSFCTFGCFCPEGM
VLDDTSKNYTCVPVTQ CPCKLSGVAYAPGEVTIAACQ----TCQCTMGHWECSERSCPRS
CSLEGGSFVTTFDARHYRFHGTCTYILVQSPELPDGGSLMATYDKSGYSHSETSLVAVIY
MSSQD--KIVISQDEVITNNGDTKWLPYKTRNITVFRQTSTHLQMATTFGLELLIQLQPV
FQVYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAETHCSVLVKTDTVFEKCHTTVDPKPFYK------VGG--TCR
LTGRLQKATGVAGGWGGVGGCRG-GRR----------GWGGRV-GQAA------------
----VGVARGYFQITTSRACNPTCLSLSDHTAECHPSAMPVDGCNCPEGTYLNHKAECVR
KAQ CPC-LLDNYKFVLADQS-TMVNGIICYCINGRLKCPGRSLTL-LES CSAPKTFQACS
QSSENKFGA---ACAPTCQMLATGIPCVPTKCEPGCVCAEGLYEDANGQCVPPEE CPCEF
AGVSYPLGAELNTDCKTC----TCSRGKWTCQQSAQ---------CSST CTLYGEGHMVT
FDGQRFVFDGDC---EYI-------LATDGCGANDSQPTFK----ILTENVVCGKLGVTC
SRAIKIFLGGLSIVLEDKNYTVSGEEDPHVHFRVKASSLNLMLDVTISSKYNLTLIWNKH
MTVFIKIARS-SQDALCGLCGNYNGNMKDDFETRS KYVASSELEFVNSWKENPLCGDAT-
-FVVDPCSLNTFRR SWAERKCSIINSQTF------AACHNQVYHLPYYEACVSDTCACDT
GGDCECLCDAVAAYAKACLDKGVCVDWRAPDFCPVYCDFYNTHTQV-GSGEYQYTQ--EA
NCTWHYQPCLCPGWPQ-SIPD---------------------------------------
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-------------------SPTGNATGPGAE---G-NLQS---SPDKGWCSTWGASHFST
FDYGAYDFSGTCNYVFAATCKNAMP-AFSVQLRRGPDGNIFRIIVELGASVITVENGTIS
IKDVGVVSLPYTSNGLQMTPYGQSV-QLAAKQLELELVVLWGPDPHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGNADNDFMS
E-DG K---LLEPHKFAALQKLDDPNEICTYEAIPSTPMLHA----------K--DAQTCA
QLLALVSP ECDV--PKKLLVHSCQVDMVACNPPGQPNCSCATLSEFSRRCSMAGQPVSRW
RGPGL CS-------LG----S CPASLEYQECGVVCTRTCSNPRHSCPSSCTFGCFCPEGT
VLDNLSTNHTCVPLSQ CPCMLNGVVYSPGEVTAATCQ----TCQCTTGHWTCMEKPCPGT
CSLEGGSFVTTFDTRPYRFHGTCTYILLQSPQLPDEGTLMAVYDKSGYSHSETSLTAVIY
MSQKD--KIVISEDEVITNHGDTKWLPYKTGNITIFRQTSTHLQMATTFGLELVVQLRPI
FQLYITVGSQFQGQTR---GLCGNFNGDTTDDFMTSM GIDEGTATPFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSELLRKGGAFEKCHTTVNPTPFYK------RCIYQACN
YEETFPHICAALGTYAQACASQGILLW----------GWRSSV-DNCT------------
----VP CTGNRTFSYNSQACGRTCLSLSDHEAECHPSAMPVDGCNCPEGTYLDHRGECVR
KAQ CPC-LLDSSKFLPSDQS-TMINGVICYCVNGRLSCSGQPQNL-LAS CPAPKTFQSCD
QSAEDKFGA---ACAPTCQMLATGTACVPTKCEPGCACAEGLYEDPSGECVPPEQ CPCDF
AGVSYPGGAKLHTDCKIC----TCSQGRWACQQGAH---------CPST CVLYGEGHMVT
FDGQRFMFDGNC---EYT-------LATDDCGTNSSQPIFK----VLTENIICGKLGVTC
SRAIKTTLGGLSITMADGSYVVHGE-DSHVHFQVQLSALSLVLDVDIPGRLNMTLIWNKH
MSVSIKISRS-SEDALCGLCGNANGNMKDDFETR SRYVASSELEFVNSWKESPLCGDMR-
-AAVEPCSLNAFRRSWAER KCSIINGQTF------AACHSKVYHLPYYEACVHDACGCDT
GGDCECLCDAVAAYAKAC------------------------------------------
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MLRVQQLL--LLLLFGGSLINAGAWTGDATD---SNTEDSLQSSPEKGWCSTWGDGHFST
FDHHQYDFKGMCNYVFTSTCGDALP-TFSIQLRRDGDGNISRIIIELGASVVTVNKAIIS
VRDIGVVSLPYTSNGLQITPYGRSV-RLVAKQLEMELVAIWDQDDHLL------------
--------------------------------VLVEKKYMGKLCGLCGNFDGKADNEFLS
E-DG K---LLEPHKYATLQKLDDPSEICAHEAIPSPTILK-----------T-RYAQICN
QLLTLVSP GCDV--PKEPLVLSCQADMADCAQPGQQNCSCATLSEYSRRCSMAGRPVRNW
RTPAL CP-------VS----Q CPANQVYRECGEVCGKTCSNPQHSCSSFCTFGCFCPHGT
LLDDISRNHSCVPVSQ CPCMLNGVVYGPGEITRTACQ----TCQCTMGRWTCTEQPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYTLLQSPQLPNEGTLMAVYEKSGYSHSETSLVSIIY
MSKKD--KIVISEDEMVTNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLELVVQLQPI
FQVYITVGPRFKGKTR---GLCGNFNGDTTDEFTTSM GIDEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHTVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSSRGTLLL----------GWRNSV-DNCT------------
----VP CTGNRTFSYDSKACDRTCLSLSDRETECHTSAVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDSNKFVQADQS-TMINGVICYCINGRLSCPRQAEMF-LAS CPEPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGIACVPTKCEPGCTCPKGLYENSEGQCVPAEE CPCDF
AGMSYPGGSELHTDCKTC----TCSQGRWTCQLNEQ---------CPST CVLYGEGHIIT
FDGQRFVFDGNC---EYT-------LATDDCGSNSSQPTFK----VLTENVICGKSGVTC
SRAIKITLGGLSITMADRNYTVSGE-EALVHLQVKPSPLNLVLDIGIPGRLNLTLVWNKH
MSVSIKIRHA-TQDALCGLCGNSNGNMKDDFETRS KYVASNELEFVNSWKESPLCGDAS-
-YVVDPCSLNTFRRPWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPVYCDFYNIHTLV-GENQYQYAQ--EA
NCTWHYQPCLCPGSLG-SFLDTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHKEGTCVPCA
SPTTTPSP-ATTGSQPTTAT---PTSTEFSSSSSA-ATPVGPSYLPGLPTP---------
-----------------PASAPSSTE-------EVTDWTTPKKSTVSSGE----------
-----------------------------FPQTT-VAT---------TALTSPLP-----
----PTSIPKSTPSMLPVTQATTKPTVSSL---SPSTNTTAQ-FTESTTVT--------P
ITSERPGMSTSQ----QP------------------------------------------
------------------------------SSSYWKLLT---------------FYPS--
VTLASGLLDLLS--------THPSWS----------------------------------
----LQLA----------------GR------GATDYLPR---LRGKCNS----------
--NSLPGFLC--------LLCQFQY-----------------------------------
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-------------------------------

--MLRPWL---LLSCCGALLSTGLADTSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASIVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEAVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLELHKFAALQKLDDPGEICTSEDIPNTHVRQV----------Q--HAQICT
QLLTLVAP ECSV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAPLRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGACTYILLQSPQLPEDGALMAVYDKSGFSQSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACASRGVL VDNCSECPGVSWGPNSPS-PAGPSQRGL----IPG
SSTAVP CTGNTTFSYNSQACERTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIINGVTCYCINGRLSCPQRPQMF-LAT CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTCT---C-SRGRWACQQGTH---------CPST CTLYGEGHIVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRD-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQPS----------TTGSRPTQVWPTTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSKHT-PA----------SPTQTPL------
---------------LPATLTSSKPTASSGDEPMER------------------------
-----------TA---AG------------------------------------------
--------------ESPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----PGT----T--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-DQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGMTTEYTTPQTPHITHSPP------------VG-TLVASTGP
TTAIS--------------FQTTTIYPTPSHPQTTLPT--HVPPFSTSSVTPNTHTVIIP
THAQMSTSASIHSTPTGTIPPQ--------TTVKSTRSTHTAPPMTATTSRTS-QD----
-------SS----SFSTAKTS----TSLHSYASSTHHPQ----------------VTPTS
TTNITPKSTSTGTGTPVTH-----------------------------------------
-------------------------------------TNSATSSRTPIPITTHSPPI---
--GS--TSVSSTGPMTATSVKITT-TYPTPSHPQTTLPTHVPAFSTSLVTPSTHTVITPT
HAQMSTSSSIHSKPTGTITSPT-------------------------------TLT----
------------------------------------------------------------
----------------------ATGSTRTAPTMTGTISGTSQA--QNSISTAKTSTSLHS
HASSTHHPEITLTS-------------------------------------TTTITPNPT
STGTSTPVAHTTL-VTSSRPPPPFTTLS---PPTGS--SPVSSTGPMTATSFQTTTTYPT
PPHPQTTFPTHVPPFSTSLV----------------------------------------
-----TPTTHTVIIPTHSQTSTS----------------------TSIHSTPTYIIPSST
TVKATGSTHTAPPMTGTTSGTSQVH----SSFSTVKTSTSLHSH----GSSTHHPE-ITP
-TSTIAITPN----------PTSTDTGTP-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------VAHTTSAT
------------------------------------------------------------
----------------------------SSSHPN--------FYHHHP--QSH-----Q-
------YRNRHP--------------------CGPHHLSHQ---------QQATYTLHH-
---TLPTYRE-------QSVSSTGPITATSFQT-----T------------------TTY
PTPSHPQTTLPTHVPPFSTSLVTPTTHTVITPTQTQMSTSASIHSM--------------
--PTG--TI-SPPT---T-VKATGSTHTAPPMTAT-------------------TTLSSF
STAKTSTSLHSHTSSTHHPQVT-PTS--TTITPNPTSTGTSTPVAHTTSATSSRLPTTFT
TH-----SPPTESSPVSSTGPITATSFKTTTTYPTPS--HPQTT-LPHRSSLSPLLPDQL
PHA-----VIHPYPTHQVFIFLSIPSDQQEPFLQ--------------------------
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--GLGVVSLPYTSNGLQIMPFGQNV-RLLAKQLELELEVLWGPDSYVM------------
--------------------------------VLVEKKYMGKLCGLCGNFDGNTTNEFLS
E-DG K---PLEPYQYAALQKLDDPNEICAYEAIPQPYNP QE------------EHAQTCT
RLLSLVSPGCNV--SRESFVQSCQVDMATCTRPGQDNCSCATLSEFSRQCSMAGQAVSNW
RAPGFC S-------VG----Q CPANQVYQECGPA-YRTCSNPGHTYQGYCTFGCFCPNEM
VLDDLSENHTCVPVSR CPCMLNGALHAPGEVTTSACR----TCLCAEGLWECTEQPCPGR
CSLEGGSFVTTFDGRPYRFHGTCTYTLLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX--XXXXXXXXXXXXXXXXKWLPYSTRNITIFRQTSTHLQMATDFGLELVIQLQPV
FQAYITIEPQFQGQTR---GLCGNYNGDTTDDFLTSMG IVEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLN KVCAETHCSVLVTKGSVFEKCHSVVNPNSFYK------RCVYEACN
YEQTFPYICAAVGAYAHQCAFKGVLLG----------DWRDSV-DNCT------------
----VSCTGNRTFSYNSQACNRTCVSLSDPTLECHTSAVPVDGCNCPEGTYLNHKAECVR
RSQCPC-QLDTQEIVLAGQS-KINNGAT---------CTPWPQML-LATCTDPKTYQSCS
QSSENKFGA---ACAPTCQMLATGIACVPTKCESGCVCPEGLYEDANGQCVPPENCSCEY
GGDSYPSGAELDTGCETC----TCKEGKWECQQGAS--------C-ASTCTLYGEGHVIT
FDGQRFVFDGSC---EYTLAT-------DGCGANNTQSTFK----IVTENVICGNSGVTC
SRAIKLFLGALSIVLEDKTYEVSGY-DPQVSFQVQPGSLYLELDIYIAGKYNLTVTWNKH
MTVFIKASRASTQDAFCGLCGXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX-
-XXXX------XXXXXXXXXXXXXXXXXXXXX XXXXXXXXXVDYMAYFEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRSPDFC PVYCDFYNSHQG--SSGEYQYAQ--EV
NCTWHYQPCLCPDQLH-NYPRSNIEG----------------------------------
------------------------------------------------------------
---------------------------------------CYN CSQNEYFDSSEGTCVPCA
LSTTPLPP-STTLLTTAX-------XXXXXXXXXX--XXXXX---XXXXXXX--------
--X--XX------------------------------XXXXXXXX---------------
---------------------X---XXXX-------------------------------
------------------------------------------------------------
---------------------------------------------------------XXX
XXXXXXXXXXXXXXXSPLSTTAVTPRLTSA------L-----------------TPTTTT
PTVTHATSQTTAPHL------STA------------------------------------
-----TRTTAQATETLPAT-----------------------------------------
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-------------------------------

--MLRPWL---LLSCCGALLSTGLADTSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGNISRIIVELGASIVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEAVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLELHKFAALQKLDDPGEICTSEDIPNTHVRQV----------Q--HAQICT
QLLTLVAP ECSV--SKEPFVLSCQADVAAATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAPLRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGACTYILLQSPQLPEDGALMAVYDKSGFSQSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLVRAGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACASRGVL VDNCSECPGVSWGPNSPS-PAGPSQRGL----IPG
SSTAVP CTGNTTFSYNSQACERTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TIVNGVTCYCINGRLSCPQRPQMF-LAT CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTCT---C-SRGRWACQQGTH---------CPST CTLYGEGHIVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRD-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SIPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCM
PATTPQPS----------TTGSRPTQVWPTTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSKHT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------ESPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----PGT----T--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-DQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGVTTEYTTPQTPHITHSPP------------VG-TLVASTGP
TTAIS--------------FQTTTIYPTPSHPQTTLPT--HVPPFSTSSVTPNTHTVIIP
THAQMSTSASIHSTPTGTIPPQ--------TTVKSTRSTHTAPPMTATTSRTS-QD----
-------SS----SFSTAKTS----TSLHSYASSTHHPQ----------------VTPTS
TTNITPKSTSTGTGIPVTH-----------------------------------------
-------------------------------------TNSATSSRTPIPITTHSPPI---
--GS--TSVSSTGPMTATSVKITT-TYPTPSHPQTTLPTHVPAFSTSLVTPSTHTVITPT
HTQMSTSSSIHSKPTGTITSPT-------------------------------TLT----
------------------------------------------------------------
----------------------ATGSTRTAPTMTGTISGTSQA--QNSISTAKTSTSLHS
HASSTHHPEITLTS-------------------------------------TTTITPNPT
STGTSTPVAHTTL-VTSSRPPPPFTTLS---PPTGS--SPVSSTGPMTATSFQTTTTYPT
PPHPQTTFPTHVPPFSTSLV----------------------------------------
-----TPTTHTVIIPTHSQTSTS----------------------TSIHSTPTYIIPSST
TVKATGSTHTAPPMTGTTSGTSQVH----SSFSTVKTSTSLHSH----GSSTHHPE-ITP
-TSTIAITPN----------PTSTDTGTP-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------VAHTTSDH
------------------------------------------------------------
----------------------------MPVPHLPYTP--NGFFPSPL--LGT-----L-
------YANAFL--------------------------AKQ---------V-S-------
---GLPV----------------G-LSPANLDL-----S------------------L--
--------HWLTHAPVTAALLASPQSDTCQKPSPA----------A--------------
--PLG--AQ-RMSG---L-AGPQGSSSTALPPSAE-------------------RD----
------------IKVRHSPCLA-PKD--LLKVK---------------LDLATRAPAP--
---------------------WYSCQFSGPRLFPAST--WSHAY-ERVHCSPGHEMPGDR
TH-------LRPRPRPPNLTFLGCPSLPSWVFLS-QQP-------PRDWVPR-----MHR
PPPGG---------NATVGFVVSHVGS--SSLLQAEGILVWVPP----------------
------------------------------------------------------------
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-------------------------------

--MLRPWL---LLSCCGTLLSTGLAATSYTSPGLWRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVIGLPYTSNGLQITPFGQSV-RLVAKQLELELEVMWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGNVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTSEDIPNTHVRQA----------Q--HAQICT
QLLTLVAP ECNV--SKEPFMLSCQADVAAATQPGPQNSSCATLSEYSRQCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSSNHTCVPVTQ CPCLLNGAMYAPGEVTIAALRRWRGL----------WERPCPGH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGTFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRTGTVFERCHATVNPTPFYK------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-DNCRGVLGPQAVEPKL
VLPAVP CTGNTTFSYNSQACERTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILADQS-TIINGWDCEGPPASSECPDCVPFFPAAS CQAPKTFKSCN
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTCT---C-SRGRWDCQQGTH---------CPST CTLYGEGHVVT
FDGQRFVFDGNC---EYI-------LATDGCGANDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-ESHVQLSVRPGTLSLVVDISVPGRYNLTLIWNRH
MTILIRITRA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDMS-
-FVADPCSLNAFRSSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPGQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHKEGVCVPCM
PATTPQPS----------TTGSRPTQVWPTTGTS---TTIGLLSST-GPSS---------
------------------------------------------------------------
-----------------------------SSKST-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------SSTATK
PTVTQATTRAT------ASTSSPA------------------------------------
-----TTSTAQSTTRTTVTP----------------------------------------
------------------------------------------------------------
----------------------------------PPPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-SQELPGTTATQTTGP--RP---------------------------
----------------------------TPESTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTGMTTEYTTPQTPHITHSPP------------VG-SPIASTGP
MTTTS--------------FQTTTANSTPSHPHTTLPT--HVPPFSTSSVTLNTHTV-IP
THAQMSTSASIHSMPTGTIPPQ--------TTVKSTRSTHTAPPMTATTSRTS-QD----
-------NS----SFSTAKTS----TSLHSHASSTHHPE----------------VTPTS
TTTITPKSTSTGTGTPVTH-----------------------------------------
-------------------------------------TTSATSSRTPTPITTHSPPI---
--GS--TSVSSTGPMTATSFQTTT-TYPSPSHPQTTLPTHFPAFSTSLVTPSTHTVITPT
HAQRSTSSSIHSVPIGTIPPPT-------------------------------TVK----
------------------------------------------------------------
----------------------VTGSTHTAPPTTVTTSRTSQAHTPSSFSTAKTSTSFYS
HASSTHHPEITSTS-------------------------------------TTNITPKST
SARTSTPVAHTTS-ATISEQHTPFTTHS---PHSGS--SPGTTTGPMTTTSFKTTTTYPT
PSHPQTTLHTHVPPFSTSSV----------------------------------------
-----NLSTHTVITPTHSQTSTS----------------------TSIHSTPTDIIPSST
TVKATGSTHTAPPMTGTTSGTSQVH----SSFSTVKTSTSLHSH----GSSTHHPE-ITP
-TSTITITPN----------PTSTDTGTPVA-----------------------------
--------------------HTTSATSSRPPPPFTT--------------------HSTP
TGSSP--TT---SKGPTTTTSLKT---------TTTYPTPSQPHT-ILPTHIPPFSTSSV
TPS-TY-----TVITSIHPQMSTSASIHSTPTGTIPPPTMLTTTGS--THTAPPMTVTTS
GTSQVHSSFSTAKTSTSLLSHASSTHHPGFTPTSTTTITPNATSTGTRT--PVAHTTSAS
------------------------------------------------------------
----------------------------SSTIPSSTTVKVTGSAHTAPPTTAN-----TS
--GTSQVLSSFSTTKTSTS--------LHSHTSSTHHPQVTPTST--TI-TPNPTSTGT-
---GTPVPHT-------TSATSSKPPTPFTSRR-----S--PISSTGPMTATSFKTTTTY
PTPSHPQTTLPTHVPPFSTSLVTPTTHTVITPTHTQMFTSSSIPSG--------------
--PTG--TI-PPVT---T-VKATASTPTA-PLTATP------------SGTS--RALNSF
STAKTSTPLHSHTSSTHHPEVT-PTS--TTITPNPTSTGTSTPVAHTTSATSSRLPTTFT
TH-----SPPTESTPVSSTGPMTATSFKITTTSPTPS--HPQTTIPTHVPPFSTSLVTPT
THT-----VITPTHAQRSTS------------------------------TS-----IHS
TPTGT---------I----------PP--PTTVKATGSTHTALPMTVATSGTSQVPSSFS
TAKTPTSL-HSH-TSSTHHPQV-----------TPTS--------TTITPKPTTTGSGTP
VAHTTSATSSRLPTTFTTHSPPTESSPVSSTGPITAT------SFQTT-----------T
T-YPT-PSHPQTTLPTHVPPLSTSLVT-PS--TQTVITPTHAQ--------VFTSSSIPS
GPTGTIPPVTTVKATASMLTAPL-TATTSGTSRALNSFSTAKTSTSLHSQTSSTHHSEVT
PTSTT----ITPKPTTTGTGTPVAHITSATSSRLPTHFTTHSPPT-EST-----------
-PVSSTGPMT--------------------------------------------------
----------------------------------------------------ATSFKITT
TYPSPSQPQTT--LPTHVPPFSTSLVTPTTHTVITLTHAQTSTSSSIHSRLFHRSYHCYI
LP----DHHYLSNPITSSDHTSHSRSTFLHLLDDSKYSHSHHPYSR-TGV-HF-LLHPLR
ANRH----HSSSDNSQGH---SIHAHSPTKDSYHQWDQPSPELIQHNQNLYIPTFTNFFH
TPF---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

-------------------------------------------------CSTWGGGHFST
FDKYQYDFTGTCNYIFATVCDE-TSPDFNIQFRRGLDKKISRIIIELGPSVVIVEKGSIS
VGSVGVIQLPYTSNGIQIAPYGRNI-RLVAKLMEMELVVMWNNDDYLMV-----------
---------------------------------LAEKKYMGKTCGMCGNYDGYELNEFV R
E--GK---LLDTYKFAAMQKMDDPSEICLSEEIPISTIPHK------------KYAMICS
QLLNLVSPTCSV--PKDRFVIRCQLDMQDCSEPGQNNCTCSTLSEYSRQCAMSHQMVFNW
RTENFC S-------VG----K CSVNQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGT
VLDDISKNRTCVHISQ CPCTLNGKTYAPGETMKAACR----TCECVMGQWNCKDLPCPGR
CSLEGGSFVTTFDSRPYRFHGVCTYVLMKSSSLPHNGTLMAVYEKTGYSHSETSLSAMML
NLSGCLTDQVKKIKGKLSPASLFLNVLVPSGDITVFRQSSMYVQMHTNFGLELAVQTAPV
FQAYVKVGSQFKGRTL---GLCGNYNGDTTDDFMTS MDITEGTASLFVDSWRA-GNCQPA
LERETDPCSLSQLNKI SAETHCSILTKKGTVFEKCHAVVNPIPFYK------RCVYQACN
YEETFPYICSALGSYARACSSMGLILE----------SWRSMV CHQIT------------
----IT CTGNQTFSYNTQACDRTCLSLSNRALECHPTDIPVEGCQCPKGLYLNHKNECVR
KSH CPC-YLEDRKFILPDQS-TMTGGITCYCVNGRLSCTGKPQNP-AESCKAPKKYISCS
DNLENKY GA---ACAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPAEE CPCEY
GGLAYGRGEQIQTECEIC----TCTKGKWKCVQKTR---------CSST CNLYGEGHITT
FDGQRFVFDGNC---EYI-------LATDGCSVNRPISSFK----IVTENVICGKSGVTC
SRSISIYLGNLTIILRDETFAISGE-NPGVHYKVIKNALHLMFDIIIPGKYNMTLIWNKH
MNFFIKISRE-TQETICGLCGNYNGNMKDDFETRS KYVASNELEFVNSWKENPLCGDVY-
-FVVDPCSKNPYRK AWAEKTCSVINSQVF------SACHNKVNRMPYYEACVRDSCGCDI
GGDCQCMCDSIAVYAMACLEKGICIDWRTPEFCPVYCEYYNSHKRTGIDDAFSRGY-NDD
KCYWHYRPCNCPRKKTC-GESKNVKQ----------------------------------
------------------------------------------------------------
-------------------------------TSLPLSSGCYNCSHDEYFDHEEK-ILSCV
TRIPA-LDLPYIQ-NHV-----------PLSLKTEVPLAIKV-----ITKS---------
FDVNLTTEKFNLFCLYVTG--------------QVNVTTTPEP---SSPSP---EIPLIS
-------------------LKTDGTGKLYIVGC--VNN--------------KI------
TTVQPKVTKSSTTSTLPTEPSTSSATAVSV-----GTTETTN------------------
------------------------------------------------------------
----------------PTITAKITIPRTSPSQPLVTIKSTTACGASFSLITTC-T-SASK
PSWATA-QVDLFNIENENK------------------------DRHE-------------
-------TTENNQPKLTTADDGPPQF--------G---------IPGRGNVHP-V-----
-----------------R-L-F--F-P-Q-E-------L-QK-R--Q-GA--Q-N-F-R-
G-TLQ-TRP-LS-TCAFLS-VVV-T--------HI-R-TT-----LT-PP-VQH-LV-TQ
T-QTT-PATS-ISSTSVLRETS---PAT-RP-QVPLTRT-FPSSS-SSL-V-------TS
ASSASSLSST-QLGTSY----------PAREPTRA------------K-TPT-TK-VVTG
---EC-SG-HERN-KS-HPW--------P-MHP-YPFS-SHSPP----------RGVC--
-SKTI-SNHQTSDTSSL--L---NCSRKKEMSSTSKTSV-S-------------------
-TGPSPASSTGAPL---ETTSAH--------ASSPP-------------APSSPLSTRLP
STATTSTGSSTAAASTSPRPTPTTLRPRPSSPATQAAKESPVTESS------------AP
TTAKTSTLPQPASSPSST------------------------------------------
--------------VSSTWLS----SS-QPVARWCGHPSIWPWELVTPMCPYM-------
------------------------------PLMQAQSLHNSCSLKGDEYSERAMFQENEQ
RFCPQDDTQAAFTHEESAVPHTGTPVTTHKTST-----ATSISSTSKT------------
SVSTGPSPASSTG----APLETTSAHASSPPAPSSPLSTRLPSTATTSTGSS--------
-----TAAA------ST----------SPRPTPT---TLRPRPSSPATQAA---------
--KESPVTESS--------------------------------TVTTAKTSTLPQPASSP
SSTV----------S-------------------STWLSSSQP-----------------
------DMQVLEG-----QSIDTYCS--------------LKGHEYSEKAMFQK--VEAA
FTHEESAVPHTGTPVTTHKTSTATSISSTSKTSVSTGPSPASSTGAPLETTSAH---ASS
PPAPSSPLSTRLPSTATTSTGS---------------------------STAAASTSPRP
-------------TPTT--------------------------------LRP--------
-----------RPSSPATQAAKESPVTESSAPTTAKTST------------LPQPAS---
-------SPSSTVS------STWLSSSQPVARWCGHPSIWPWELVTPMCPYMPLMQAQSL
HNSCSLKGDEYSERAMFQENEQRFCPQDDTQAVFTHEE-----SAVPHTGTPVTTHKTST
ATSISSTSKTSVSTG-PSPASSTGAPLETTSAHASSPPAPSSPLSTRLPSTATTSTGSST
AAASTSPRPTPTTLRPRPSSPATQAAKE-------SP-----V-----TESSASTTAKTS
TLPQPASSPSSTVSSTWLSS-------------SQPVFTHEESAV-PHTGTPVTTHKTS-
------------TATSISSTSKTSVSTGPSPASS-------------------TGAP---
----------------------------L---------ETTSAHASSPPAPSSPLSTRLP
STATTSTGSSTAAASTSPR--------------------PTP-----TTLRPRPSSPATQ
AAKESPVTESSASTTAKTSTLPQPASSPSSTVSSTWLSS-----SQPV------------
--STH---KVPHAETAVTTEKTTATTSISSTSK-------TSVS--------TGPSP---
--ASSTGATRLPSTATTSTGSSTAAASTSPRPTPTTLRPRPSSPATQAAKESPVTESSAP
TTAKTSTLPQ--PASS----------PSSTVS--STWLSSSQPVKWEM---SSRLWTGHF
PIPAPNMGKLTGVQEFSLSLQLQ------SGAFPFCPHLQLTC-AFLLA--------AFT
HEESAVPHTGTPVTTHKTSTATSISSTSKTSVSTGPSPASSTGAPLETTSAHASSPPAPS
SPLSTRLPSTATTSTGSSTAAASTSPRPTPTTLRPRP----SSPATQAAKESPVTESSAS
TTAKTSTLPQPASSPSSTVSSTWLSSSQPEKTTATTSISSTSKTSVSTGPSPASST-GAP
LE----------TTSAHASSPPAPSSPLSTRLPSTATTSTGSSTAAAS-TSP----RPTP
TTLRPRPSSPATQAAKESPVTESSAST---------------------------TAKTST
LPQPASSPSSTVS-------------STWLSS----------------------------
--SQ------------PGKAPSQFF---CSAQLLLSSFPPT---IIPSMNRAVL-VDLCL
PHHSHCLYLAPFPSVFLCLSLLLKTFSIQTHVDFLAFS--------NS-LPMPEECQRIQ
CN-------------TRLKI------SPQQYKKRLMPI--FFAFYSCP-HSKL-SSAFLL
AVSTHKVPHAETAVTTEKTTATTSISSTSKTSVSTGPSPASSTGAPLETTSAHASSPPAP
SS---PLSTRLPSTATTSTGS-------------STAAASTSPRPTPTTLRPRPSSPATQ
AAKESPVTESSASTTAKTSTLPQPASSPSSTVSSTWLSSSQ-----------PAFTHE-E
SAVPHTGTPVTTHKTSTATSISSTSKTSV-------------------------------
---------------STGPSP-ASSTGAPLETTSA----------HASSPPAPSSPLSTR
LPSTATTSTGSSTAAASTSPRPTPTTLRPRPSSPATQAAKESPVTESSTVTTAKT-STLP
QPASSPSSTVSSTWLSSS--QPGKALCL---FPPFSERIQTAAW-RQDPQENVPFF-PGT
LSAAL-SAVFNYVTCL---TPLTIHISFFTCP-------------CSQLSSASFLAAFTH
KVPHAETAVTTEKTTATTSISSTSKTSVSTGPSP-ASSTGAPLETTS-AHASSPPAPSSP
LSTRLPSTATT---------STSFT---------HEESAVPHTGTPVTTH----------
-----KTSTATSISSTSKTSVSTGPSPASSTGAPLETTSAHASSPPAPSSPLSTRLPSTA
TTSTGSSTAAASTSPRPTPTTLRPRPSSPATQAAKESPVTES------SAPTTAKTSTLP
QPASSPSS---TVSSTWLSS--SQPVFTHEESAVPHTGT---------------------
--------------PVTTHKTSTAT-SISSTSKTSVSTGPSPASSTGAPLETTSA-----
-----HASSPPAPSSPLSTRLPSTATTSTGSSTAAASTSPRPTPTTLRPRPSSPATQAAK
ESPVTESSTVTTAKTSTLPQPASSPSSTVSSTWLSSSQPAFTHEESAVPHTGTPVTTHKT
STATSISSTSKTSGSTGPSPAS--STGAPLETTSAHASSPPAPSSPLSTRLPST------
----------------ATSPFSSALA-PTVSTMSVPTSLTTSTF----------------
------------------------------------------------------------
---------------RSAESTTHSYFQNTT-SNPYGKTSSLAVPTSVSAQSRP-------
-------------------------------

-------------------------------------------------CSTWGNGHFST
FDNYLYDFSGTCNYIFATVCDE-ISPDFNIQFRRGPNNKIARIIIELEATVIMIENGVIS
VKDVGIIRLPYTRNGIQITPFGCIT-RLVAKLMEIDLAVFWDNNDYLMV-----------
---------------------------------LIEEKYMGRTCGLCGNFDGQELNEFL N
E--GNFFSLLDPQEYVALQKLDDPTEICPFEEMVTPNVPHK------------KYARICS
QLLSVVSPSCNI--TKKGFVIRCQLDMQSCRDPGQKNCVCATLSEYSRQCAMSHQEVSDW
RNADFC S-------LG----K CPANKIYKECGSPCLRTCSNPEYTCSSYCTYGCFCPEGT
VLDDISRNRTCVPVEQ CPCTLNGKKYAPGEVMEAVCR----SCKCSMGQWSCTELPCPGR
CSLEGGSFVTTFDSRPYRFHGVCTYIIMKSPMLPHNGTLMAVYEKSGYSSSETSLTAIIY
VSGND--KIVISKNEILIDDKEIKWLPYKSGDITIFRQSSTHIQMVTPFGLEIVFQIFPL
FQAFVKAELHFRGNTR---GLCGNYNGETADDFMTS MDIIEGTAPLFVDSWRA-GHCSPA
IERDTDPCSMSQLNKM CAETHCSVLTKKDTIFAKCHIAVNPIPFYK------RCVYQACN
YEETFPYICSALASYAHACASMGLLLG----------NWRSTV-DN CT------------
----IA CTGNQTFSYNTQACDRTCLSLSNRELECHSADIPIDGCNCPKGTYLNYRNQCVR
KSQ CPC-YLKDRKFIQADQS-TIIGGITCYCINGNLSCTGRPIDP-EENCRPPKKYIS CS
SNSGSKYGA---ACAPTCQMLATGIQCVPSKCESGCVCDAGLYEKLDGTCVPPDE CPCEY
GGISYEKGEQIQTECKTC----TCARGKWKCIQNTK---------CSST CSLYGEGHINT
FDGQRFVFDGNC---EYI-------LAMDGCGMGGSPHTFK----IVTENVVCGNTGITC
TRAFKIHLGNLTITLADRTYTVSGW-NPQTEFFIEENALFLYTEITITDKYDIILVWNRH
MNLFIKISRE-TKDNLCGLCGNYNGNIRDDFET RTRYVASNELEFVNSWKENPLCGDVF-
-FVADPCNRNPYRK AWAEKKCSIINSQVF------AACHSKVHRMPYYEACVRDSCGCDT
GGDCECMCDAIAVYAKACLDVGVCIDWRTPDFCPVYCDYFNSHK--------------EL
NCTWHYRPCKCLNMSTS-ET----IN----------------------------------
------------------------------------------------------------
-------------------------------GIFSLLTGCYNCSGDEYYNPKTKSCVPCG
KCYFWEIQSPPSSSRTTPET--------RHSTSTPKTTATSS-----LST----------
-----------------TS--------------RITVSTESDT---S-------------
-----------------------------------STS--------------KI------
IQSSTTPTTETTPSTVPITST--------H-----SVTETAT------------------
------------------------------------------------------------
----------------PSTTSH----------QIITIVTTS--------------DTLLI
PNIASC-QLSNF------------------------------------------------
-------------------PETPTSS---------------------EGGFRP-A-----
----------------FN-F-L--C-S-S-R-------C-RK-N--T-KH--Q-H-----
-------NH-DT-ECXI----SL-G--------KI-G-KN-----RP-QP-AR-------
-----------------QRQ----------P-QP---PT-TPKPT-TRT-T-------SS
---------S-T----T----------STSHPTTP------------T-TPT-TT-STKS
T---------PTS-TH-TPITTI----SP-ITP-LPTV-T---P----------M-----
-------------------------------PLTTPTPV-S-------------------
-STATPTVTYTTPL---STTTPTTTTPTTTETTTPPSTT-------TTSTTTHPVTTTVP
ITATSTTTS---------------------SP----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

--MLWRWL---LLCFCGALLGAGECGGGRRAPQGPR---PAHTVPDKGRCSTWGVGHFST
FDHHVYDFSGTCNYVFAATCEDTFP-TFSVQLRRGPDGSITRIIVELGASVVTVSEGTIS
VKDIGVISPPYTSNGLQITPFGQSV-RLVAKQLELELEVTWGPDAHLMV-----------
---------------------------------LVEQKYMGQMCGLCGNFDGKATN DEEG
RWAHR---LLEPHKFAALQKLDDPSEICAFEAIPSPLHVSEGAPGGS------PRARICT
QLVTSVA PECSV--PKEPFVLSCQADVAAATQPDLGNSSCATLSEYSRRCSMERQPVRRW
RGPSL CP-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSTCTFGCFCPE GE
GGRGRRQTPPX----------XXXXXXXXAVTTAACR----TCQCTLGRWACTERPCPGH
CSLEGSSFVTTFDARPYRFHGTCTYILLQSPQLPEDGTLMAVYDKSGFSHSETSLVAVIY
LSGQD--KIVISQDEVVINNGGAQWLPYRTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYITVGPQFRGQTR---GLCGNFNGDTTDDFTTS LGIPEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNPTPFYKGARCQPMCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-ENCT------------
----VP CTGNSTFSYDSQACERTCLSLSDRAAECHASAVPVDGCNCPNGTYLNHKGECVH
KAQ CPC-TLEGYKFILAQQA-TVINGATCYCTNGRLSCPQRPQMF-LAS CPTPKTFESCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCANGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQATH---------CPST CTLYGEGHIVT
FDGQRFVFDGSC---EYI-------LATDGCSANDSQPTFK----ILTENVVCGKAGVTC
SRAIKLFLGGLSIVLADRNYTVSGE-EPHVQLRVRPDALSLAVDVGIPGRYNLTLVWNRH
MAVLIRITRA-SQDAICGLCGNFNGNMKDDFETR SRYVAASELEFVNSWKESPLCGDMR-
-FVADPCSLNTFRSSWAER KCSVINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-GHGEYQYMD--KA
NCTWHYQPCLCPDQPQ-SVPGSNN------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSRDEYFNHEEGVCVPCV
PPTTLQPP-TTALMAGLPHSGSRPTQVWPTTGA----TTIRLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSKST-TA----------GPTQTPL------
---------------LPATLTPSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPLRPTTAVTPQATSGQTPTATL-----------------RSTATS
PTVTQATTQVT------ASTTSPA------------------------------------
-----TKSTAQYTTRTTA------------------------------------------
------------------------------------------------------------
-----------------------------------TPAT-----SGTSPTLG--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------SR-CHGMPTTSRGTG----------------------------------
------------------------------------------------------------
-----------TPV--ATTTSATSSRPPTPFTTHSPS---------T--GG-SPVSSTGP
ITATS--------------FKTTTTHPTPSHPQTTLST--HVPPFSTSSVTPSTHTVITP
THPPMSTSPSIHSTPTGTMPPQ--------TTVRATGSTHTARPMTATTSGTS-HI----
-------HS----SFSTATMS----TSLHSHASSTHHPE----------------TASMS
PNTITPKTTNRETGTPVAT-----------------------------------------
-------------------------------------NTSATSS----------------
-----------QPPATITPYKTTT-THPTPPHPQTTLSTHVPPFSTSSVTPSTHTVITPT
HPLISTSRSIHSTPTGTTPPET-------------------------------TVK----
------------------------------------------------------------
----------------------ETGSTYTAPPMTATTSGTSQAH--SSFSTATTPTSLHS
HASSTHYPETTPIP-------------------------------------TTSSTPKPT
GTG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------TTTPMTATTSGTSHTH----SSFSTATTSTSLHSQ----ASSTHRPE-TTP
-TSSTTIIPK----------TTSRGTGTPVA-----------------------------
--------------------TTTSATSSRPPTPFTT--------------------HSPP
TGSRP--IS---STGPMTATSFKT---------TTTHSTPPHPQT-TLSTHVSPFSTSSV
TPS-IY-----TVITRTHPPISTSPSIHSTPTGTVPVPTMVKVTGT--THTAPPMIGT--
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------TI
--RTSQAHSSFSTATTSTS--------LHSHASSTHHPEITPTSN--TTITPKTTSRAT-
---SNPVATT-------TSASSSGLPTPFTTHSPAMGGS--LVSSTGPMTVTSSKTTTTH
PTPPHPQTTLSTHVPPFSTSSVTPSTHTVITSTHPPISTSRYIHST--------------
--PTG--TV-P--T---T-VRATGATHTAPPMTATT------------SGTS--HAHSSF
STATSSTSFISSSSWSPQNSSSRPPSSSSATTPLPHSSSPTTPVSATHQLHSSSSSPPSF
AP-----SS--------------------VTSHVSSSHSSPQT---------------SS
SSV-----VSTPVHSTTLSSGSH------SSFFT-RS-----------------------
----------------------------------------------TAASASGFSPSPAA
STTSRASLPHTT-SPPVSLSTL-----------LPVS-------TPTASST---------
------------------------------------------------------------
--TAS-LSTRRTTASTYPASAVSSQSTTSRFTSLTTRVPTPGF--------VSLTSGVTG
IPSSPIT-----------------------------------------------------
-----NFTTRHPGPTSL-----------STTQFLTSSLTAHGSTP-ASA-----------
-PVSSLVTTTPS---------S--------------------------SG----VCSVQE
QQEEITFK----GCVANVTVTRCEGVCTSSASFNIDTQQ-LDARCSCCRPLRSHEQQLEL
PCPDPSAPGQQ--LVLIQQVFSRCVCSSVSCGH---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------------------

--MLRLWL---LLSCCGALLSAGLANTPYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEVVWGPDSHLMV-----------
---------------------------------LVERKYVGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTFEDIPSTHVRQA----------QHAQI--CT
QLLTLVAPECSV--SKEPFVLSCQADVATATQPGPQNSSCATLSEYSRRCSMVGQPVRRW
RGPGLC S-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSNNHTCVPVTQ CPCVLNGAMYAPGEVTIAAC----QTCRCTLGRWACTERPCPGH
CSLEGGSFVTTFDARPYRFHGSCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI
FQAYVTVGPQFRGHTR---GLCGNFNGDTTDDFTTSV GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVC AETHCSVLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-DN CT------------
----IP CTGNTTFSYNSQACERTCLSLSDRATECHHSTVPVDGCNCPDGTYLN-KGQCVR
KAQ CPC-TLEGYKFILAEQS-TVINGVTCHCINGRLSCPQRPQMF-LAS CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQGTH---------CPST CTLYGEGHVIT
FDGQRFVFDGNC---EYI-------LATDGCGVNDSQPTFK----ILTENVICGNSGVTC
SRAVKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPGALSLVVDISVPGSYNLTLIWNRH
MTVLIRIARA-SQDPLCGLCGNFNGNMKDDFETRSRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAERKCSIINSQTF------AACHSK-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
PPTTPQPP-TTP---QPPTTGSRPTQVWPTTGTS---TTIGLLSST-RPSP---------
------------------------------------------------------------
-----------------------------SSNRT-PA----------SPTQTPL------
---------------LPATLTS-SPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTL----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--HTRTTTEYTTPQTPHTTYSPP---------T--KG-SPVASTGP
MTATS--------------FQTTTTYPTPSHPQTTLPT--HVPPFSTSSVTPSTHTVITP
THPQMSTSASIHSMSTGTIPPP--------TTLMATGSTHTAPPMTVTTSGTS-QV----
-------HS----SFSTAKTS----TSLLSHASSTHHPE----------------ITTTS
TTTITPNPTSTGTGTPAAHTTSATSSRMTL------------------------------
---------------------------TTRTGIPVAHTTSATSSRLPTPFTTHSPPT---
--GS--SPISSSGPVTATSFQTTT-TYPTPSHLQTTLPTHLPPFSTSLVTPTTHTVITPT
HAQMSTSASIHSTPTGTVPPPT-------------------------------TLK----
------------------------------------------------------------
----------------------ATGSTHTAPPTTLTTSGTSQA--PSSFSTAKT------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------STSLHSH----TPSTHHPE-VTP
-TST-TVTPN----------PTSTGTGTPVA-----------------------------
--------------------HTTSATSSRLPTPFTT--------------------HSPP
TGSSP--IS---YTGPVTATSFQT---------TTTYPTPSHPQT-TLPTHVPSFSTSLV
TPS-TH-----TVITPTHAQMSTSASIHSTPTGTVPPLTTLTATGS--THTAPPMATTS-
AIS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAPSSVST-----------------------------------------------
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-------------------------------

MLGVQLLLLLLLLSFEGALLSAGEWVSARP---------CLAGAPDKGWCSTWGNGHFST
FDHLEYNFLGRCNYIFTATCKAASP-TFSVQLRRGPDGNISRIIVELGASVVTINKATIS
IKDIGVISLPYTSNGLQITPYGQNM-QLVAKQLELELVVIWG PDAHLMEEQDGSL----G
EPETCK-----------Q-----ETPIHAAP QVLVERKYMGRLCGLCGNFDGNADNEFLS
E-E GK---LLEPYKYATLQKLDDPNEICVHEAIPSPPVPQT----------A--YAKICT
RLLNLVS PECNV--PKDPLVRSCQEDMATCAQPGQQNCSCATLSEFSRRCSMAGQPVRSW
RGP A----------PG----Q CPANQVYQECGEVCVKTCSNPYHSCSSFCTSGCFCPDGT
LIDDISKNHTCVPVSQ CPCMHNGVVYGPGQIIASTCQ----TCQCTMGHWTCTEQPCPGH
CSLEGGSFITTFDARPYRFHGTCTYTLLQSSQLPDEGTLMAVYEKTGYSHSETSLAAIIY
LSKKN--KIIISEDEVITNNGDIKFLPYTTSNITVFRQTSTHLQMVTTFGLQLVIQLQPV
FQVYITVGPQFRGQTK---GLCGNFNGDTTDDFMTSM GIDESTASLFVDSWRA-GNCPPA
LARETDPCSMSQLNKVCAET HCSMLLKKGSVFERCHAVVNPTPFYK------RCVYQACN
YEETFPHICAALGAYVHACSTWGVPLW----------GWRSIV-DNCT------------
----VSCTGNRTFSYDSQACGRTCLSLSDHAAECHASAVPVDGCNCPSGTYLNHKAECVQ
KSQCPC-LLDGNKLIEAYQS-TVVKGILCYCISGRLSCPKQAEMF-LASCPAPKTFRSCS
QSSEDKFGA---ACAPTCHMLATGIDCVPTKCEPGCVCAKGLYENSNGQCVPAEE CPCDF
EGVSYPGGAILHNDCKTC----TCSQGRWTCQQNAY---------CSST CVLYGEGHVVT
FDRQRFVFDGNC---EYT-------LATDDCGANSSQPTFK----ILTENVICGKSGVTC
SRAIKIFLGGLSITMADRNYTVSGE-DPLIHFQMKPSSLHLILDVDIPGKANLTLVWNKH
MSVSIKIRRT-TQDALCGLCGNYNKNMKDDFETRS KYVASSELEFVNSWKENPLCGDAS-
-YVADPCSLNTFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDTCGCDM
GGDCECLCDAVAAYAKACLDKGVCVDWRSPDFCPIYCDFYNTHTRV-NENKYQYAR--EV
NCTWHYQPCLCPGSLE-SFLDTNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDKYFDHGTGTCVPCG
KSRTHLPH-TGSRPPEVQPS---TAT--------TTT---------T--------RSYSS
SSPATAVGPTYSPG-L------SASSSAPPSTDGETGWTTKKPTIS----LG--------
-------------------------GSTQTT----MAIT-------PQPTS-PLTPIATA
SSTAPG---------VTMTQATTEP---TASSLSPATKSTAQ-FTTHTTVT--------R
I-----------------------------------------------------TSAMPG
TS------PTQGE-SQPMG-SQGTRA----------------------------ASSD--
----HGIADPAR------------------------------------------------
-----------KEAFLN--------FS---------------------------------
-----------------------------------------------AGGTKENQVT---
-----------------------------KKGRYQGHQY---------------------
------------IEEPVADPYGQKTRQK-------------------SKSGNTIVDLT--
------------------------------------------------------------
------HQTSESQ-RPTAP-----------------------------------------
---------------------------------PKTSSWTSP------------------
-TTPSLV-----------------------TSTTLSL---------PFSFS-TTPQTTGP
SLGTS--------------IKTT-AFPTPSTTEASLTS--LPP-FSTSSVTLTSPITPTG
PS--MVPSYST-TSPSINILMTTTSKGTGHP--------HTEPTLSSTTRATS-QG----
-------YS----SYTTAST-----SPHPSHSNSTPHHQ----------------STLGS
ATTISPESTSGITSTQEAH-----------------------------------------
-------------------------------------PTSGTPSSPHTPFTTHSSPT---
--VPVSNTAHTTGIPTGTSVIT--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------PKST
SSTTGTTVVHTTS-GTPSSPHTPFTTNS---LPTASVSTIPHTTGPHTGTSVHTTTTVPT
PPAPQTSLTLPVS---TIVI----------------------------------------
-----IPTNSQTT-AST--------------------------------SRTPSIIFPTT
TVEGTVSTPTAPPLTSTASATSKVQ----TSFSTASTSPSLVTH----PSPTPHHP-SSS
-VLATTITPQ----------TTSTVPETSVP-----------------------------
--------------------QTISETPSSSYTPFTT--------------------HSLS
TISVPNTPH---TIGPSSGTSVLT---------TITFPTPSGPQT-SFTTSVATFSTSSA
SPT-SQ-----VLVTPTSSHMVPSTA---T---------IIPS-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------TTITGPPQTSPTITSN-----TS
--VTTQAQSSLSTARTSPS--------HFSPPSSTPYHHQTTLTPATTTTPPKSTSSTA-
---GTPMVHT-------TSGMPSSPHTPLTTHSPPTVSISNSPHTTYLPLVTSVQTT-TI
PIPSSPQTLLTSPVSTSSAHSLTSTSEMLSTPSSEHIMS---------------------
--TAS--TF-HIK----D---------TVPSLISTT-TA-----------TS--PAQSSF
TTVKTSPE------WSPPSSATQSISP---------------------------------
--------------------PTSS----SPHFSPSP------TSVSPTNIPNSSPWWPGT
SPT-----SSLPSPLLTTSSLPS-GSFPA--SSS-TSP-----------PPT-----PSS
SSYTPTLSSVS-HVPLFTGPTTVSH----PPSVS-----ASVP--PTAAS----------
-TPVNASLLPLGTSSPP--SST-----------------------LSTIHVSPTPT-HGP
A----SSTK----------------FP--------------ST----SKTTSR---VPTS
S-P---FS---------------SQSTTSHFTSLTTQALTPGF--------LSSTLGVTA
LPS--SP-----------------------------------------------------
---VTTHTT-----SQE-----------PTSVFLSSSITRPGST-SPSTTE---------
-SPSTEGSPLPT---------P--------------------------SG----ACSLRE
EQQQITYH----GCTANVTLGRCEGFCASSVSFNIDTQQ-METRCGCCHPIGTYEKQLLL
PCPDPNTPGQQ--LKLTVQMFSSCACSHPRCRN---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

--MLRPWL---LLSCCGALLSAGLANTSSTSPGLQRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYYFSGTCNYIFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVVSLPYTSNGLQITPFGQSV-RLVAKQLELELEVVWGPDSHLMV-----------
---------------------------------LVEQKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFTALQKLDDPGEICTLEDVPSTHVRQA----------QHARI--CT
QLLTLVAP ECSV--SKEPFVLSCQVDVAAATQTGPQNSSCATLSEYSRQCSMVGQPVRRW
RGPGLCF-------TA----QAGWGVSLE-PGRGEWETV-------SPTQAPRRPSPAGT
VLNDLSNNHTCVPIAQCPCVLNGAMYAPGEVTVAALRRWRGLCRCTLGRWACTERPCPGH
CSLEGGSFVTTFDAMPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPV
FQAYVTVGPQFRGQTR---GLCGNFNGDTTDDFTTSV GIAEGTATLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNP-----------RCVYQACN
YEETFPHICAALGDYVHACSSRGVLLW----------GWRSSV-DNCT------------
----VP CTGNTTFSYNSQACERTCLSLSDRAAECHPSAVPVDGCNCPNGTYLNHKGECVR
KAQ CPC-TLEGYKFILAEQS-TVINGVTCHCINGRLSCPQRPQMF-LAS CQAPKTFESCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----TCSRGRWACQQGTH---------CPST CTLYGEGHVIT
FDGQRFVFDGNC---EYI-------LATDGCGVNDSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPGALSLVVDISVPGRYNLTLIWNRH
MTVLIRIARA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPDFCPIYCGFYNTHTQD-SHGEYQYTQ--EA
NCTWHYQPCLCPSQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFDHEEGVCVPCS
NPDGM-----------SAHPGSRPTQVWPMTGTS---TTIGLLSST-GPTP---------
------------------------------------------------------------
-----------------------------SSNRT-PA----------SPTQTPL------
---------------LPATLTSIKPMASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTVTL----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGA--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTRTTTEYTTPQTPHTTHSPP---------T--AG-SPIASTGP
MTATP--------------FQTTTTYPTPSHPQTTLPT--HVPPFSTSSVTPGTHTVITP
THAQMATSASIYSTPTGTIPPP--------TTLKATGSTHTAPPMTPTTSVTS-QA----
-------PS----SFSTAKTS----TSLHSHTSSTHHPE----------------VTPTS
TTNITPNPTSTGTRTPVVH-----------------------------------------
-------------------------------------TTSATSSRLPTPFTTHSAPT---
--GS--SPFSSTGPVTATPFQTTT-TYPTPSHPQTTLPTHIPPFSTSLVTPSSHTVITPT
HAQMATSASIHSTPTGTIPPPT-------------------------------TLK----
------------------------------------------------------------
----------------------ATGSTHTAPPTTLTTRGTSQA--PSSYSTAKTSTSLPS
HTSSTHHPEVTPTS-------------------------------------NTI-TSNPT
STGTGTPVAHTIS-ATSSRLPTPFTTHS---RSTGS--SPISSTGPMTVTSIQTTTTYQT
PSHSQTTLPTHVPPFSTSLV----------------------------------------
-----TPSSHTVITPTHAQMSTS----------------------ASIHSTPTGTIPAPT
TLKATGSTHTAPPMTPTTSVTSQAP----SSFSTAKTSTSLHSH----TSSTHHPE-VTP
-TSTTNITPN----------PTSTGTRTPVA-----------------------------
--------------------HTTSATSSRLPTPFTT--------------------HSPP
TGSSP--FS---STGPVTATSFQT---------TTTYPTPSHPQT-TLPTHIPPFSTSLV
TPS-SH-----TVITPTHAQMATSASIHSTPTGTIPPPTTLKATGS--THTAPPTTLTTR
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAPSSYSTAKTSTS--------LPSHTSSTHHPEVTPTSN--T-ITSNPTSTGT-
---GTPVAHT-------ISATSSRLPTPFTTHSRSTGSS--PISSTGPMTVTSIQTTTTY
QTPSHSQTTLPTHVPPFSTSLVTPSSHTVITPTHAQMSTSASIHST--------------
--PTG--TI-PAPT---T-LKATGSTHTAPPMTPTT------------SVTS--QAPSSF
STAKTSTSLHSHTSSTHHP-EVTPTSTT-IT-PNPTSTGTRTPVAHTTSATSSRLPTPFT
TH-----SAPTGSSPFSSTGPVTATPFQTTTTYPTPS--HPQTTFPTHIPPFSTSLVTPS
SHT-----VITPTHAQMATSA------------------------------S-----IHS
TPT-------------------GTIPP--PTTLKATGSTHTAPPMTPTTSVTSQAPSSFS
TAKISTSL-HSH-TSSTHHPEV-----------TPTS-------TTNITPNPTSTGTRTP
VAHSTSATSSRLPTPFTTHSAPTGSSPFSSTGPVTAT------PFQTT-----------T
T-YPT-PSHPQTTLPTHIP-PFSTALVTPVTH--TVITPTHAQ--------MSTSASIHS
TPTGTVPPPTTLKATGSTHTAPPTTLTTRGTSQAPSSFSTAKTSTSLHSHTSSTHHAELT
PTSTTNITHITPNPTSKGTGTPVAHTTSATSSRLPTPFTTHSRST-GSS-----------
-PISSTGPTT--------------------------------------------------
----------------------------------------------------TTSFQTTT
TYPTPSHPQTT--LPTHIPPFSTAFVTPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX----XXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX-PQ-LLPPT-
--------------------------S----------PPTPP-VQAPEPL----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

--MVQRWL---LLSCCGALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFST
FDHHVYDFSGTCNYLFAATCKDAFP-TFSVQLRRGPDGSISRIIVELGASVVTVSEATIS
VKDIGVISLPYTSNGLQITPFGQSV-RLVAKQLELELEVVWGPDSHLMV-----------
---------------------------------LVERKYMGQMCGLCGNFDGKVTNEFVS
E-E GK---FLEPHKFAALQKLDDPGEICTFQDIPSTHVRQA----------QHARI--CT
QLLTLVAP ECSV--SKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRW
RGPGL CS-------VG----Q CPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGT
VLNDLSNNHTCVPVTQ CPCVLHGAMYAPGEVTIAAC----QTCRCTLGRWACTERPCPRH
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGFSHSETSLVAVVY
LSRQD--KIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI
FQAYVTVGPQFRGQTR---GLCGNFNGDTTDDFTTSM GIAEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSVLLRTGTVFERCHATVNPAPFYK------RCVYQACN
YEETFPHICAALGNYVHACSSRGVLLW----------GWRSSV-DNCT------------
----IP CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNHKGECVR
KAQ CPC-ILEGYKFILAEQS-TVINGVTCHCINGRLSCLQRPQMF-LAS CQAPKTFKSCS
QSSENKFGA---ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEE CPCEF
SGVSYPGGAELHTDCRTC----SCSRGRWACQLGTH---------CPST CTLYGEGHVIT
FDGQRFVFDGNC---EYI-------LATDVCGVNNSQPTFK----ILTENVICGNSGVTC
SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRH
MTVLIRIARA-SQDPLCGLCGNFNGNMKDDFETR SRYVASSELEFVNSWKESPLCGDVS-
-FVADPCSLNAFRRSWAER KCSIINSQTF------AACHSKVYHLPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-GHGEYQYTQ--EA
NCTWHYQPCLCPSQPQ-SVPGSNI------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQDEYFNHEEGVCVPCM
PPTTPQPP----------TTGSRPTQVWPMTGTS---TTIGLLSST-GPSP---------
------------------------------------------------------------
-----------------------------SSNRT-PA----------SPTQTPL------
---------------LPATLTSSKPTASS-------------------------------
-----------------G------------------------------------------
--------------EPPRPTTAVTPQATSGLPPTATL-----------------RSTATK
PTVTQATTRAT------ASTASPA------------------------------------
-----TTSTAQSTTRTTMTL----------------------------------------
------------------------------------------------------------
----------------------------------PTPAT-----SGTSPTLP--------
----------------------------------------------------------K-
------------------------------------------------------------
-----------ST-NQELPGTTATQTTGP--RP---------------------------
----------------------------TPASTTGPTTPQPGQPT-------------R-
----PTA--TET-T--QTRTTTEYTTPQTPHTTHSPP---------T--AG-SPVASTGP
VTATS--------------FHATTTYPTPSHPETTLLT--HVPPFSTSLVTPITHTVITP
THPQMSTSAYVHSTPTGTIPPP--------TTVKATRSTYTAPLMTATTSRTS-QA----
-------HS----SLSTAKTS----TSLHSHASSTHHPE----------------ITPTS
TTNMTPKSTSRGTGTPVAH-----------------------------------------
-------------------------------------TTSATSSRPPTPITTHSSPT---
--GS--SPLSSTGRMTATSLKTTT-TYPTPSQTHITLPIHVPSFSTSSVTPSTHTVITPT
HPQMSTSASNHSTSTGTIPPPT-------------------------------TLT----
------------------------------------------------------------
----------------------ATGSTHTAPPITVTTSGTSQV--HSSFSTAKTSTSLLS
HVSSTHHPEITTNS-------------------------------------TTTITPNPT
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------ST-APSMTATTSGTSQSP----SSFSTAKTSTSLPYH----TSSTHHPE-VTP
-TST-TITPK----------PTSTETGNPVA-----------------------------
--------------------DTTSATSSRLPTPFTT--------------------HSPP
TGSSP--FS---STGPMTATSFQT---------TTTYPTPSHPHT-TLPTHIPPFSTSLV
TPS-TH-----TVITTTHAQMATSASIHSMPTGTIPPPTTLKATGS--THTAPPMTPTTS
GTS---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----QAPSSFSTAKTSTS--------LHSHTSSTHHPEVTPTST--TNITPKHTSTGT-
---RTPVAHT-------TSATSSRLPTPFTTHSPPTGSS--PISSTGPVTATSFQTTTTY
PTPSHPQTTLPTHIPLFSTSLVTPSTHTVITPTHEQMSTSAHIHSM--------------
--PTG--TI-PPPT---T-LKATGSTHTAPPMTVTT------------SGTS--QTHSSF
STATASSSFISSSSWLPQNSSSRPPSSP-ITTQLPHLSSATTPVSTTNQLSSSFSPSPS-
--------APSS-----------V------SSYVPSSHSSPQTSSS---------SVGTS
SSF-----MSAPVHSTTLSSG------------------------------S-----HSS
L---------------------STH----PTT-----ASVSASPLFPSSPAAS-------
-TTIRATLPHTI-SSPFTLSAL-----------LPIS-------TLTVSPTPSSHLASS-
------------------------------------------------------------
T-IAF-PSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF--------VSLTSGVTG
IPT-----------------SPVTNLTT--------------------------------
---------RHPGPTSS-----------PTTRFLTSSLTAHGSTP-ASA-----------
-PVSSLGTPTPT---------S--------------------------PG----VCSVRE
QQEEITFK----GCMANVTVTRCEGACISAASFNIITQQ-VDAHCSCCRPLHSYEQQLEL
PCPDPSTPGRR--LVLTLQVFSHCVCSSVACGD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

MLGPRLLLL-LS--CAGPLLVTGKWASAWP---------HQRLSPGKGQCSTWGTSHFST
FDGRAYEFSGTCNYVLAATCREASP-TFSVQLRRGVRGSVSRIIVELGATAVTVSKGSIS
VKDVGVVSLPYTRNGLQITPHGHSV-QLVAKQLELELVVTWGPDSHLMVSAAGSP-----
----------AWGGLSCT-----LGPSSVHPQVLVERKYMGQMCGLCGNFDGKADNEFLS
E-DG K---LLEPHKYAILQKLDDPNEICSHEAIPRVFIPQN----------A--HARI CA
QLLDLVSPECNV--PKEPLLLSCQADMAECDWPGQRNCSCATLSEYSRRCRMAGQPVSRW
RSP A----------LG----Q CPANQIYQECGTPCIGTCSNPQHSCSSTCTSGCFCPDGM
VLNDLTTNHTCVPISQ CPCMLGGALYQPGQATRAACR----TCQCSMGRWACTEKPCPGH
CALEGGSFVTTFDARPYRFHGTCTYILLQSPWLPDEGTLMAVYDKSGYSHSETSLVAVVY
LSRKD--KIMISEDETITNHGDTKWLPYKTHNITIFRQTSTHLQMATSFGLELVIQMQPV
FQVYITVSPQFRGQTR---GLCGNFNGDTTDDFTTSA GLGEGTASLFVDSWRA-GNCPTA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHTAVNPQPFYK------RCVYQACN
YEETFPHICAALGAYAQACSSRGVLLW----------GWRSSV-DNCT------------
----VP CSGNRTFSYNSTACDRTCLSLSDRTAECHSSSVPVDGCNCPEGTYLNHKAECVR
KAQ CPC-LLDGSKFVLADQS-TIINGAICYCTNGRLSCPRQQEMF-LAS CMAPKTFQSCS
QSSEDKFGA---ACAPTCQMLATGSTCVPTKCEPGCVCAKGLYENPQGQCVPPEE CPCEY
AGTSYPGGAELHTDCKTC----TCSQGKWTCQQNAH---------CSAT CVLYGEGHMIT
FDGQRFVFDGNC---EYI-------LTTDGCGANSSQPTLK----ILTENVICGNSGVTC
SRAIKISVGGLSITMADRNFTVSGR-EPAVHFQVKPSNLNLILDLGMPGRFNLTLIWNKH
MSVSIKMYRI-SQDPLCGLCGNYNGNMKDDFETR TQYVAPSELEFVNSWKENPLCGDAS-
-YVVDPCSINTFRRSWAER KCSIINSQSF------AACHSKVYHLPYYEACVRDTCGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRTPSFCPIYCDFYNTHKHV-G-NEYQYTP--TA
NCTWHYQPCLCPGRLE-SFPDTNSFTQISTGSPTLPITNAFIHSHSSSFALHIHSLTSTS
GHTHTHIFTSTSIHSSTRSFTKALTCTHQQTRPQGQPQLWAGTWPHKTVLQELLSWAGST
AAKGHKHCRPHRRRPGAQQGVSETGGKRGMRALPCSAPGCYNCSQDEYFNHQEGICVPCS
KSRLRLRL-SLGHMCGVPVC---GDGVWPVC-ARGVVS----------------AVQP--
----STVGPEPRPCQWGKADSALGWLVDGEVEGWGGGWEGGGEDRGG-------------
--------------------GKERGGQRSLT----APFSC------SAADTYVY------
--------------------------------------THTH-T---------------H
THTHMPQPWFQEWTGNTRDGPVA-------------------------------RSSWLV
TD------PDHSA-SPPEG-SG--------------------------------RTTA--
--RGCGEKGPL-------------------------------------------------
-------PTAPGRALLTLRPQL--------------------------------------
-----------------------------L------------------------------
-----------------------------STGPQPTEVL---------------------
------PTTPGVSSGPPALPTGPVQTAS--PATAPSTPPSSPSSPEG---GTTVTTPRKS
TVSSG--------GKSSSRCPGASAFPMSRPTQLLKTAY-------NSNWPLAVA-----
-VAGCLNDARHAQ-QPNLPTHSSSKALSMG-RLMT-HTSLHSPPVPQGQLSQMTLQDLRA
RQERQ----------RLLLR--------GGGTETGRRSWGHGPG------EA------T-
GDGDVLSSSPD--------------------SSHT-----------TMAVS-AL------
---------------------------------------------------STSPGTPTA
T-----------------------------------------------------------
---------------ASATVT----GLTVTQATSEPTAS----------------SPSPA
TTSTAQYT---------AR-----------------------------------------
-------------------------------------TTEGPPTSAGPAV----------
---SPSH---------------SE-SQPTGAVAQTPGPAPSPTSRRS-------------
-----------------------------------------------------DVM----
------------------------------------------------------------
-----------------------GGGTHWD-----------------------------A
IGSQVPHNPRGTAISPQAEEHRTTCAGRLNSPTTAQEQGPSTGTGYTRPPPSDQIILTTQ
QHGTESTTPHTWS-TLTSHNSQPSSA--------LAA-----STQAPQGTSPHPTTTPQT
PSGPQTPLPSLFPSSTS-------------------------------------------
---------ASTP-SSHEATIT-----------------------TSAHLGPSASTAQTT
A-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VLPI---TTVKTTGPTLTA---------SG-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------TT
--ATTQSHSSLTPKTTSAH--------LLSQPSTLHH--------------PT--STES-
---PTTRATG-------RPP-ANTGSASPSTHSPSTTSVSTTAHSTGPPTATPLQTTSTL
YTPSTPQTSLTSLLPTSSSSS--SFS--SSGPPSSHRTIPPSVSPAVSGISSSG--STDT
LLPAS--PV----------SGT-GPAPTTPPLTPST-----AAP--SAPHSS-------L
STD---------RTSTPTRGPLPALSP---------------------------------
--------------------PPSS----LTTLHPHPSL--ATS-PPPASFPPSSTVWPRT
SLS-------LPTPTVPTTLLAS-STAPP--ASS-PPP-------TSQYAPT-----PSS
VPPS---PSVTRPTALP----------------------PSSSP--TAAS----------
-TALNTPLLPLLHASPT--THA-----------PPASTPD--LALSTWRT----TL-HIP
T----SSAS--------AS--------------------Q-STTAQVTSLTTH---TPSA
G-PLP-STLATITYPGAT---------VTNLTTRPPGAT--QLPTSM-------------
FPAGSSP-----------------------------------------------------
---PTGSPS-----AST-----------PK----------------PPAPTSPW------
-G-SSAMTSPPR---------P--------------------------SG----PCGLLE
QERQITYQ----GCEVNVTLTHCEGLCSSSVSFNTDTLQ-VDTHCSCCYPLGTHEKQLLL
PCPDPSAPGRQ--LTLTLQVFSGCACRPWNCRD---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

-----------IMLGPRLLLLLSCGGALLGAGEWGPTLSATPTGSDKGWCSTWGAGHFST
FDGHVYDFPGTCNYIFSATCKDASP-TFSVQLRREPSGSISRIIVELGASVVTVQKAVIS
VKDVGVVSLPYTSNGIQITPFGQSV-QLVTKQLELELVVMWGPGTHLM------------
--------------------------------VLVEKRHRGRLCGLCGDFNGERMDEFLS
E-E GK---PLEPHVYAALQTLDDPNEICTYEAVPSPWVPQA------------EHAQT CS
QLLTLVSPECHV--PKETFVLSCQVDMAACVPPGRRDCSCATLSEYSRQCSMAGQAVSNW
RGPGL CS-------LG----Q CAANQVYQECGEACVRTCSNPQHACSSFCTFGCFCPGDT
VLDDISKNHTCVPVTQ CPCVLNGVVYAPGEVMTSACQ----TCQCTMGQWKCTEQPCPRR
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEGGSLMASYDKSGHSHSETALAAVIY
KSSQD--KIVISQDEVLTDKGNTKWLPYKTRNITVFRQTSTHLQMATTFGLELVIQLKPV
FQVYVTVGPQFRGQTT---GLCGTFNGDTTDDFMASTGIVEGTASLFVDSWRT-GNCPAS
LERETDPCSMSQLNKVCAETRCSVLVREGTVFEKCHATVNPRPFYK------VGR-----
-----------------TCGAC---------------GGRRQG-APTA------------
----TPCTGNQTFGYDSRACGRTCLSLSDRAAECHPSAVPMDGCNCPEGTYLDHEARCVR
KAQCPC-LLDGSKFIRADQS-AMVNGVICYCINGRLSCPGRPQML-LATCSAPKTFQSCN
QSSENTFGA---ACAPTCQMLASGIPCVPTKCEPGCVCAEGLYENARGQCVPPEE CPCEF
AGVSYPRGAQLHTDCKTC----TCSGGRWTCWQSAR--------C-SST CTLYGEGHVVT
FDGQRFMFDGSC---SYVLTTVSTPSPQDSCGANSSRPTFK----VLTENVVCGKSGVTC
SRAIKIFLGDLTIVLADRTYTVSGG-DPHVHFRVQTGSLNLVLDITIGSRYNLTLVWNKH
MTVYIKITRA-AQDALCGLCGNYNGNMKDDFETRS KYVASDELEFVNSWKDSPLCGDAS-
-LTLDPCSLNAFRHVWAER TCNIINSQTF------AACHSQVYRLPYYEACVRDTCGCDT
TGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPVYCDFYNGHTS--GDSAPTQTQ--DT
ICTWHYQPCLCPGNPQ-SVPGANIEG----------------------------------
------------------------------------------------------------
---------------------------------------CYNCSRHEYFDHSKGTCVPCG
NPPLPSSA-T-----P------------------------------IVP-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------GTGTRPTHTTTPLTRTTQTPSSVTTT-----------------K-----
------------------------------------------------------------
---------------TS----------SVPGPHPS-------------------------
------------------------------------APVHT-------------------
----------------------------------------QS------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------SPTPHTT
VSPTPPRSGTTTPVTHTATNTATATKSHTPHTTHSGP---------TPSAVPTSARSTGP
PTGTS--------------FRTTSARPTPPRPEATRST--RPAPSTTSSVTHTTHRLITP
THSETHQPHSTGSPPLPSSATP-------IVPGTGTRPTHTTTPLTRTTQTPS-------
------S-------VTTTKTS----SVPGPHPSAPVHTQSSPHSPH--------------
--HRLPNAPQVRNHDPRDTHRDKHGHRDQVPHTPHDALRPDA------------------
--------VCCTLQRAVDRSPHGHVLPHHL---RQANPAAPRGHTVHAP-----------
-------------------------------------------------C-PLHHVLGDA
HNP---------------------PTHHPNPLGDPP----------------APLHRQ--
--PSPP------LLG-N------------AHRARHWHTA---------HAHDHATHSDHP
------------------------------------------------------DA----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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MLRVRQLL--LLLLFRGPLIDAGAWTGDVTD---SNTEDNLQSSPEKGWCSTWGTGHFST
FDGHEYNFQGMCNYIFTATCGDDVPATFSIQMRRDMDGNISRIIIELGASVITVNKEIIS
IRDIGVVSLPYTSNGLQIIPYGQSV-QLVAKQLELELVVMWGPDAHLT------------
--------------------------------VLVETKYMGKLCGLCGNFDGKIDNEFLS
E-DG K---LLEPHKYATLQKLDDPNEICAHEAIPSPIVLK-----------T-RYAQICN
QLLTLVSPG CDV--PKETLMLSCQADMATCARPGQPNCSCATLSEYSRRCSMTGQPVRNW
RTPGL CP-------MS----H CPANQVYQECGEVCVKTCSNPQHSCSSPCTFGCFCPHGT
LLDDISGNQSCVPVNQ CPCMLNGLVYGPGEVTRTACQ----TCQCTMGRWMCTKQPCPGH
CSLEGGSFVTTFDSRPYRFHGTCTYTLLQSPQLPNEGTLLAVYDKSGYSHSETSLVAIMY
LSKKD--KIVISEDEVITNNGDTKLLPYKTHNITIFRQTSTHLQMATTFGLELVFQMQPV
FQVYITVGPQFKGQTR---GLCGNFNGDTTDDFTTSM GIDEGTASLFVDSWRA-GNCPAA
LERETDPCSMSQLNKVCAET HCSMLLRKGSVFEKCHSVVNPQPFYK------RCVYQACN
YEETFPHICSALGAYAHACSARGILLW----------GWRNSV-DNCT------------
----VP CTGNRTFSYDSQACDRTCLSLSDRETECHSSPVPVDGCNCPEGTYLNHKAECVH
KAQ CPC-LLDDYKFVQADQS-TMINGVICHCINGRLSCPRQAEMF-FAS CPEPKTFQPCS
QSSEDKFGA---ACAPTCQMLATGIACVPTKCESGCVCPKGLYENSDGQCVPAEE CPCDY
AGVSYPGGFELHTDCKTC----TCSQGRWTCQLSTQ---------CPST CVLYGEGHIIT
FDGQRFVFDGDC---EYT-------LATDDCGANSSQPTFK----VLTENVICGKSGVTC
SRAIKISLGGLFITMADSNYTVSGE-EPLVHLQVKPSPLNLVLDIDIPGRLNLTLVWNKH
MSVSIKIRRA-TQDALCGLCGNANGNMKDDFETRS KYVASSELEFVNSWKESPLCGDAS-
-YAVDPCSLNTFRRSWAER KCNIINSQTF------AACHSKVYHLPYYEACVRDACGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPIYCDFYNTHTLV-GENEYQYAE--ET
NCTWHYQPCLCPGSLG-SFPDINT------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSQNEYFDHREGTCVSCA
PPTTTPPP-TTTGSRPTTET---TISTEFHSSTSA-NTPVDPSYLPSLPTP---------
-----------------PPSAPSSTE-------ELTVWTTPTESTVSSGE----------
-----------------------------YPQTS-TAA---------TPPTSHLP-----
----PTSIPKSTPTGLPVTQATSKPTASSL---SSSTKTTAE-FTESTTVT--------L
LT-SMPGMSTSR----DKTS----------------------------------ASY---
------------------------------------------------------------
------------------------------------------------------------
----------------------------TTQLQSTSYHLTTISNGPTNGP----------
--QYFSH------------WKLLTFYPSITLRSGL---------LGFLATHTSWDLQLT-
--------------------------GRRAPDYLPGLCG---------------------
----------------------------------KRDS--NSLPGFLRLLC-----QFQ-
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--------------------------------------NTLSTDEQRGWCSTWGAGHFST
FDHHVYNFSGTCNYVFAAICKDPSP-TFSVQLRRGSDGTTARIIMELGSSVVTVQSGVVS
VKDVGVVSLPYTSNGLQITPFGQNV-RLVAKQLELELEVLWGPDGYVMVRTAGVLSGGGG
R-------GPMWGR----------CQHCRCPQVLVERKFMGKMCGLCCPANQGVQGSAAQ
P-----------TSDPVPTKAQLPRLLHLWLLLPRRVR------------------ASAA
RSLGLHSPNPQMN--QEEGTAGN--PTSSSPCPAM------------RACGCVHGQKRRW
GLSAPSVQSGHRHLLGSATHQGVVSWVWASWGRVPLR---CPWQLRMQHAAPGSPSPAGM
VLDDLSKNQTCVPITQCPCMFNGAVYAPGEVTSSSCR----TCQCSEGLWKCTEQPCPGR
CSLEGGSFVTTFDARPYRFHGTCTYILLQSHQLPEEGSLMAVYDKSGYSHSETSLVAIIY
LSGQD--KIMISQDEVITNNREVKWLPYKIGNITIFRQTSTHLQMATDFGLELMIQLQPV
FQAYVTVEPQFRGQTRAHPGLCGNYNGDTTDDFMTSMG ITEGTASLFVDSWRA-GNCPTA
LERETDPCSMSQLN KVCAETHCSVLVKKGSVFEKCHSVVNPQPFYK------RCVYQACN
YEETFPHICAALGAYAHLCASHGVLLW----------DWRSSV-DNCT------------
----IPCTGNTTFSYNSEACNRTCMSLSDHTLECHPSAVPVDGCNCPEGTYLNHKAECVR
KGPVSLPSWDSHEFIFGRDSPPLSTAPPCYCINGRLTCSRKAQTL-LATCTAPKTFQSCS
QSSESKFGA---ACAPTCQMLATGIACVPTKCEPGCVCAEGLYEDANGQCVPPSNCSCEF
GGASYPTGAELNTDCQTC----TCKQGKWVCQQSTS---------CASTCTLYGEGHMIT
FDGQRFVFDGNC---EYT-------LTTDGCSTNDSQPTFK----IVTENVICGKSGVTC
SRAIKLFLGALSIVLADKTYTVSGH-DPQVSFQVQPGSMHLVLEVYIAGKYNLTLTWNKH
MMVLIKVSRT-SAQVTPVRAGGLDGNPKADSGSRMG LTG--WWTLVSKGKRSPPVADSGN
GLVAKVCMAHR VLG--AG---PAHTRLSN------LDAHPQVYHMPYYEACVRDTCGCDT
GGDCECLCDAVAAYAKACLDKGVCVDWRSPDFCRECLGVDGIKRHQ-AVPSL--PP--QG
PHPSHPRQASCPASAEVSFPCSPAYHAS--------------------------------
-----------------------------TTHHSDDANLVPTAWPSTE------------
------------------------------------------------------------
-----AQP-TTPA-TPTPRTSGLLSSARP--STSPGATPVGPTATASLPATSM-------
----------------ASPQAPSSAQ----------------------------------
-------------------------------TDT-VPT---------APTKPAVS-----
----P-------------------------------------------------------
------------------------------------------------------------
-------------GESPRSTTAITPRVTSAPTPTSTR-----------------RVTATR
PTVTQATSHPTASHPTTATQ----------------------------------------
-------TTAESH-R-----------AHHSSYGTPTALEETSSILPATHQRRRAVPH--H
SRRSVP---------------------------GA---------QRRTGPPGDAQAW---
----------------------------------PRPRH--SPTNKLPP-----CL--HP
TATGHGPHT----------------------------SAVPASHGE--------------
-YSVG-----------------SSSIVSCASAEELDTGRASGGLRLETH-ELKIKGVENM
GGFGCKFRKQST---KE---------------------------IREGDPKA-----VET
KQTRVHTTKTTGTERGILAN---------SEERTNRSDLGSGGPR----RRQTR------
--VTPLL----------------------------S----------PTAAS-TSTAATGT
TT---------------------GRQTRTRSPEITPPT--RIPPLATSSVTPTSHRVTTP
AAEATTSSPSS-PPPTGTSLSTTTGTKT-------KLPTPVPPDATSSVTPTSQQV----
-------T-----TLTPAAIKS--SSSPLTTATSRHTTA----------------A-P--
----STGTRVRATGTPVPE-----------------------------------------
------------------------------------TTLPVSHSQPHTTFTTLSQPT---
--VSASSSSRSTGPPTGTSFKTTT-TLPIPSSPKTTLPTPAPPVATSSVTPTSQQVTTLT
PAAIKSSSSPLTTA----------------------------------------------
------------------------------------------------------------
------------------------------------TSR---------------------
---------------------------------------------------PTTAAPSTG
TQATGTPVPETTSPVSHSRPHTNFTTPS---QPTVSASSSSRSTGPPTGTSFKTTTTLPT
PSSPETTLPTPVQPLATSSV----------------------------------------
-----TATSHPVTTPTTETISSS----------------------PS-SSPHTGTSR---
-------TTTAAPST---------------------------------------------
--------------------GTRSATGTPVPE----------------------------
--------------------TTSPVSHSQPHTTSTT--------------------LSQP
TVSASSSSR---ST-GPNGTSFKT---------TTTLPTPSSTKT-KLPTSVPPVATSSV
TPT-SH-----QVTTPTRSSSSPLTTATSR------PTTAAPSTGTRST-----------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------PSTSPFTKT-----TS
--ATGSSHTSVSTVKTTIS--------QVSFAPSTAPA--SSTSPPHTTITPKPTSRAT-
---GTLVPET-----S-LSATHSQPHTSFITLSPPTLSPSSSSHSTRPPLGTSFKTTTSF
PIPSGPRTTVSTRFPPFATSSVTLTSHRVTTLTAEAITSSPSS-----------------
AWPTG--TS-RPTTAAPS-TGPRP-TASTSPLTKTT------------SATG--PPHSSL
STAKTSPHVSHSSSL-------LPPLPT---ISHPSSSFTSLP-----------------
---------------SV-----SQIPFT--------------TSVSLPHLPFSSTHFPST
SSI-----PSVSTLATSTSSFS--SGIPAS-FSS-ST------------IAS-----VST
YPSQSAVPTTQHSKQPSSAYHTPSSPG--QV--------------VVSNSTSSFTHSPHS
TTSLSSSVSPPF------------------------------------------------
-----------------------TSSPHSSTLPPTST----------LHLSSPTSSVPVS
S-SAIGPSTSSTTPSAVPSSPLSSQS-TSLSTPLTSLTA--------TPGIVSSTLGATA
SPSSPATMLTT-------------------------------------------------
---------NQTSTTGL-----------LTTLVLTSSITAHGSSSIPV-PESFS---TQG
SSISSVVTSLSS---------P--------------------------TG----ICSVRE
YEKEITYL----GCTANVTMTRCEGSCASSASFNIHTKQ-VDIQCGCCHPLRSYEKQLVL
PCPDPSAPGDQ--LVLTVLVFSSCACSSQACRD---------------------------
------------------------------------------------------------
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-------------------------------

-------------------------------------------------CSTWGGGHFST
FDKYQYDFTGTCNYIFATVCDE-TSPDFNIQFRRGLDKKIARIIIELGPSVVIVEKGSIS
IRSVGVIQLPYASNGIQIAPYGRNI-RLVAKLMEMELVVMWNNDDYLMV-----------
---------------------------------LAEKKYMGKTCGMCGNYDGYELNEFV R
E--GK---LLDTYKFAALQKMDDPSEICLSEEIPISAVPHK------------KYAMICS
QLLNLVSPTCSV--PKDRFVIRCQLDMQDCNEPGQDNCTCSTLSEYSRQCAMSHQMVFNW
RTENFC S-------VG----K CSANQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGT
VLDDISKNRTCVHISQ CPCTLNGKTYAPGETMKAACR----TCKCVMGQWNCKDLPCPGR
CSLEGGSFVTTFDSRPYRFHGVCTYILMKSSSLPHNGTLMAVYEKTGYSHSETSLSAIIY
QSTKD--KIVISQNDLLTDDDELKRLPYRSGDITVFRQSSMYVQMHTNFGLELAVQTLPV
FQAYVKVGSQFKGRTL---GLCGNYNGDTTDDFMTS MDITEGTASLFVDSWRA-GNCHPA
LERETDPCALSQLNKI SAETHCSILTKKGTVFEKCHAVVNPIPFYK------RCVYQACN
YEETFPYICSALGSYARACSSMGLILE----------NWRSSM-DN CT------------
----IT CTGNQTFSYNTQACDRTCLSLSNRALECHPTDIPIEGCQCPKGMYLNHKNECVR
KSH CPC-YLEDRKYILPDQS-TMTGGITCYCVNGRLSCAGKPQNP-AENCKAPKKYISCS
DNLENKY GA---ACAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPAEE CPCEY
GGLAYGRGEQIQTECEIC----TCTKGKWKCVQKTR---------CSST CNLYGEGHITT
FDGQRFVFDGNC---EYI-------LAMDGCSVNRPISTFK----IVTENVICGKSGVTC
SRSISIYLGNLTIILRDETFAVSGE-NPGIKYKVKKNALHLMFDIIIPGKYNMTLIWNKH
MNFFIKISRE-TQETICGLCGNYNGNMKDDFETRS KYVASNELEFVNSWKENPLCGDVY-
-FVVDPCSKNPYRK AWAEKTCSIINSHVF------SACHNKVNRMPYYEACVRDSCGCDI
GGDCQCMCDAIAVYAMACLEKGICIDWRTPEFCPVYCEYYNSHKRKGIDDAFSYGY-NDD
KCTWHYRPCNCPNQNY--------------------------------------------
------------------------------------------------------------
--------------------------------KYVNIEGCYNCSHNEYFDHEEERCMPCA
VQPKV-TRSSTTS-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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--SL----------PTVPSTSSATTVSLE-------------------------------
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-TTNP-TI----------------------------------------------------
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----------------------GE-------TQGSKTLPAVSTAPDKGWCSTWGAGHFST
FDGHVYDFPGTCNYVFAAICEDASP-TFSVQLRRGPSGNISRIIVELGASVVTVQKAVIS
VKDVGVVSLPYTSNGLQITPFGQSV-QLMAKQLQLELVVMWGPGSHLLVRTPAAREGWGS
RVQRFAWAHLGFVGGSRC--------PPAHPQVLVEKRHMGKLCGLCGDFNGKQTDEFLS
K-EG K---LLEPHTYAALQTLDDPNEICTYTPVTSPRVP QA------------EHAQTCT
QLLTRVAPKCNV--PKEPFVQSCQVDMAECAQPGQQDCSCATLSEYSRRCSMAGQAVSSW
RGPGLC P-------VG----P CPANQVYQECGEACIKTCSNPQHTCSSFCTFGCFCPKGM
VLDDVSKNHTCVPVTQ CPCTLSGVDYAPGEVVTAACQ----TCRCTMGHWTCAEQPCPRR
CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPDGGSLVASYDKSGYSHSETALAAVIY
VSKED--KIVISRDEVLTNNGNAKRLPYKTRNITVFRQTSTHLQMTTAFGLELVIQLEPV
FQVYVTVGHHFRGQTR---GLCGTFNGDTTDDFMASTG IVEGTASLFVDSWRT-GNCPAS
LERETDPCSMSQLN KLCAETHCSVLVRDGTAFERCHATVNPRPFYK------RCVYQACN
YEETLPHVCAALSDYARACATHGILLR----------GWRNSV-DNCT------------
----TPCTGNQTFGYDIGACGRTCLSLSDHAAECHPSAVPVDGCNCPEGTYLNHKAQCVR
KAQCPC-VLDSNKFILADQS-AMVNGVICYCVNGRVSCPGRPQML-LATCSAPKAFQSCG
DSSENTFGA---ACAPTCQMLATGTPCVPTKCEPGCVCAKGLYENASGQCVPPEE CPCEF
AGVSYPRGAELHTDCKTC----TCFRGKWTCWQSAR--------C-SST CTLYGEGHVVT
FDGQRFMFDGSC---GYILTT-------DGCGANDSQPTFK----VLTENVVCGKSGVTC
SRAIKIFLGGLSVVLADRNYTVRGE-DPQVQLRVSTGSLNLVLDVAIGGRYNLTLVWNKH
MTVFIRITRA-TQDALCGLCGNYNGNMKDDFETRSN YVASSELEFVNSWKDSPLCGDAS-
-LALDPCSLNAFR RSWAERKCNIINGPTTTPPPPSPPCHGQVYRLPYYEACVRDACGCDT
SGDCECLCDAVAAYAKACLDKGVCVDWRTPDFCPVYCEFYNTHAR--GDGAHQYDQ--EA
NCTWHYQPCLCPEHPQ-SLPDTNTEG----------------------------------
------------------------------------------------------------
---------------------------------------CYNCSRHEYFDQSTGTCVPCM
PPPTTPRP-TTEGAAG------------------------------TVP-----------
-QEVRGEGA-YSLPPADPPQP---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PPGPPSRR------A---------------------------------------GL
TGSSVQRESAEGSGESPRTTSAITTRATSAPAPTATL-----------------KSTATG
PTVTQATTKSTASTL------SSG------------------------------------
-----TQSTSRSTDYTTALPRTPDTSETSTGRPPS---KHTHTPVPKKGQEHTC----RE
P-----DQ----SCRGLRG--A-EQQRQTTHARTPSNPVTRETKQTETPTSHESSISYK-
------SEHTLPHSTNTTQKETLTTKGETTPSRPHTPLTSHSPPNPSVSTTAQ-------
--TTAPP-----------------------------------------------------
------------TGISF---RTTTAQPNTSHPETTL----------STHAAPSTTSSV--
--TPTT-----------LPIH---------------------------------------
-------------------------------------------------NE-TSSAPKTT
VSYTPPTTGTP--TSVTSTAMASTIKGHTPLTSHPTP---------TPPVS-TTTHTTGP
PTGTT--------------LRTTSAKPTASRPETTVST--HSVTSTTSSVTPTTHRVITP
THPETPSSPSPATNPGSTSAPP-------HVPSTGTQPTHTTPPLTRTTHTPS-------
------S-------LSTAKTS----TPREPYPSVPIHNETSSAPKT--------------
--TVSYTPPTTG--TPTSVTST--------------------------------------
-----------------------------------AMASTIKGHTPLTSHPTPTPPVS--
------TTTHTTGPPTGTTLRTTS-AKPTASRPETTVSTHSVTSTTSSVTPTTHRVI---
--T---------------------PTHPENPFTLSP----------------ATHPGSSS
GRPHIP------IPG-TQPTHTTLSLTRTTHTPSSLSTA---------K--TSTPREPYP
------------------------------------------------------SVPIHN
ETSSAPKPTVSHTP-------------------------------------P--------
TTGTPTSVTAMAT-ATTIKRHTPLTSHS---TPMPPGSATTHTTGPPTGTSFRTTTTRLS
PSRPETTLSTHAAPST--------------------------------------------
-TSSVTPTTHRVITPTHPETPSSPSPATHPSS----------------------------
----TSAPLPYP------------------STET---------------SSAPKP-TIAH
-TSPTTGTP-TSVTATATATATTTKRHTP-L-----------------------------
--------------------TS---HSAPTPPVSTT----------THIPGPPT------
------------------GTTLRT---------TSAKPTPSRPKT-TLATHTVTSTTSSV
TPT-TH-----RVITPTHPETPSSPSPA-THLGSTSESPHIPSTGTQPTHTTPPLTWTTH
T----PSSLSTAKTSTSRISYPSVPIHHETSSAPKPTISHTPQATGTLTSVTATATSTAT
TSKQHTLLTSHSA--PMLSVSTTAHTTGPPTGTSLRTTSTQPNTSRPETTLSTHAAPSTT
SSVTPTTHRVITPTHKRHTPLTS-HSAPTPSVSTT-------THMTGPPTGTQPTHTTLS
LTRTTHTPSSLSTAKTSTPRASSPSLPIHHETSSAPKPTVSHT----------SPATGT-
---PTSVTAT-----ATATASTIKRHTPLTSHSAPTPSV--STTT---------------
------------------------------------------------------------
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-------------------------------

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-------------------GGCPANQEYRECGPACAPTCSNPHHSCPGACTFGCFCPEGT
VLDDLSTPHTCVPLAR CPCVLHGH--APGAVTSAACQ----TCRCALGRWECVQRPCPGH
CALEGGSFVTTFDARPYRFHGTCTYTLLQSPLLPDGGALTAVYDKAGYSHSETSLTAVIY
PAGWX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRCVYQACN
YEETFPHICAALGAYAHACASRGVLLR----------GWRASV-DNC T------------
----IP CSGNQTFSDDGQACGRTCLSLSAPEAECHASAVPVDGCICPEGTFLDHRGECVP
RTQCPC-LLDGHKLLLADQS-ATVNGAFCTCARGRLSCPARPLTL-LASCSAPKTFQTCS
QSSETKFGA---VCALTCQMLATGLPCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX---XXXXXX-XXX---------XXXXXXXXXXXXXXXXXXXXXXXXXXXEGHVVT
FDGRRFFFDRNC---EYV-------LATDGCGAKDSQPTFK----ILTENVVCGKSGVTC
SRAIKLRVGGLAIELADRNYTVRGR-EPGVAFRVAAGSPHLLL--GGPGSYNLTLVWNKR
MALLLRVERA-QQDALCGLCGNSNGNMRDDLETRGG YVAASELQAVDSWRESPLCADAR-
-PAAEPCSLNAFR RAWAERKCAIINSQTF------AACHGKVYRMPYYEACVRDACGCDS
GGDCECLCDAVAAYAQACLDKGVCVDWRAPDFCPVYCDFYNSHTRA--GGQYQYTQ--EA
NCSWHYQPCLCPGRPQ-GVPGTNM------------------------------------
------------------------------------------------------------
-------------------------------------EGCYNCSRDQYFDHEQGXXXXXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX------XX---XXXXXXX--------
-----XX-X-------------XXXX-------XXXXXXXXXXXXXX--X----------
------------XXXXXXXXXXXXXXXXXXTQDT----------PEPSPTKATISTTAT-
--------------GHTGTQATTQPTATSLSLAT---SSTARPTAHTTTLT----REPTX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXTGPPTGTSF--STTTHPPPPRTSLLS---------------TS-SVT
P-----------------------------------------------------------
------------TSQKVTTPTHPETPSTAPHTGTG-------SILPARAITET-------
-------------------------------------------TTRTTGVQTPTSTSRT-
----------------------------------SSSMAPHTPPGNLS------------
-----------VHSTP--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------THT
STSRPNSPGTGTPVTGSH--TGTPGTPSTP------------------------------
------------------------------------------------------------
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-------------------------------

Query Results

"ENSGT00760000118896_4"

ENSGT00760000118896_4