Query Results 

------------------------------------------------------------
-----MLEGDQAILQRIKKAVRAIQSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDTLLKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVIGGST-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGLKAAQSLSPFIEKLAVSVHTLRQAQEEELQKLTQLRDSLR
GTLQLESRE-------------ESLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKG
PRIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGS-GAGPWG-AAGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------CKCRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GSPKP-SAESDMSTRRDYIV-AKYVEHRFARRS-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPEGQ----APGELALHLAVRVANQASLPLVDFIIQNGGHLDAKAA

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNSAL
HCAALYNQLDCLKLLLKGRASVA--TVNDAGETALDIARKKQHKECENLLEQAQAGTLTF
PLHLDYPWGISTEPGSDSEEDEEEK-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------Q
RCALKPP--AQARWTSGRLDISNKTYETITSLGPAAPK----------------------
------------------------------------SQSEDCPPPLPVKNPSRTMAHGRV
GHAS----------------------------GDRSEIPSLSSESLGASEN--LSS--PA
SSS--SSLTSPVEPGGPNETL-PS------------------------SEEGPCEPPGPS
RPSLTSGTSPAE---MYPPVRF---------------SSESTRSYRRGG---G---CPSA
RQ-PV---------------PG--------------------------------------
-RNVRVG--FPEGDGSRTGVLLPSSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAREEVLEGDQAI

PF16746 // ENSGT00760000118874_5_Domain_0 (74, 290)

LQRIKKAVRAIHSSGLGHV-ENEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDNLMKGHLRDGRHDSKKHLEKAWKDYEAK
VAKLEKER--DRARMTGGSL-----AEMAQDTQRERRIFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKLFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GMLQLENRE-------------EHSNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGLRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEDKKCFDLVTHN
RTYHFHAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFHGEPSG-GLGSWG-GAGLNAEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIHSLTLDLLCPSELLL--ALNIGNSRFNEVMEAQLPTH
GGPKP-SPESDMSARRDYIV-AKYVEHRFVR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-KPEPQRLWAAICSRDLLAVLEAFANG
QDFGQLLPGPDGQ----ASGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASQASLPLVDFLIHNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLKGRAPVG--TVNEAGETALDIARKKQHKECEELLAQAQAGTLTF
PLHMDYPWGLFTEHGFDSEDDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPLKLP--AQAHWASGKLDISNKTYETIARLGPATSQ----------------------
------------------------------------SQSEDCPPPLPAKNSSRTVSSGRV
GRSS----------------------------GDRSDVPSLSSESLEASEN--KGS--PA
SSS--SSLTSSVEPGGPNQSP-PS------------------------PEEGLREPPGAS
RPGLASGTTPAE---VYHPVRF---------------SSESTRSYRRGGRSLED--SPSA
RQ-PL---------------SR--------------------------------------
-RNIPVG--LTEEDGSKTGVLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAREEILEGDQA

PF16746 // ENSGT00760000118874_5_Domain_0 (73, 289)

ILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEELQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGTEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLGGGV
P--LQAPKDEHECEAWVSVLQNSKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
LIAE------------------VKSRP-------GNS---QCCDCGA----AAGV-----
-------QGRGLNREAPPRAS----LTTP--IFPRLQL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFARRC-TPEPRRLWTAICNRDLLLVLEAFANG
QDFGQPLPGPEAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKATDGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDVARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTGEDLSSPAAAA-FA----SKLQKC

PF16746 // ENSGT00760000118874_5_Domain_0 (51, 292)

RGA------V
GALEESLDGDQAILQRIRKYVKAIHVSGLTHV-ENEEQYSEALENFGNNHLSQNNHELST
GFLNLAVFTREVTALFKNLVQNLNNIVSFPLDSLLKGQLKDSRMDSKKQIEKAWKDYETK
VGKMEKEK--ERARLAGVIQAEPSAAEVAEDTQKERRLFQLHMCE-YLLKASESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQNLYPFIEKLAVSLHSLHQAQEEEVKQ

ENSGT00760000118874_5_Linker_0_2 (292, 351)

LTQTRDALR
SILQLESKE-------------ENLSRKNSG---SGYSIHQHQGNKQYGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKSGFLYKKS
DGIRKV--WQKRKCGVKYGCLTISHS--TINRPPVKLNLLTCQVRPHAEEKKCFDLVTHN
RTYHFQAEDEQECVVWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSNAFKGEPNGGAAS-A--GSGADGSVQELTKL

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

VISE------------------VKNMP-------GNK---QCCDCGA----PDPTWLSTN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLL--AVSVGNTRFNEIMEATLPTQ
DCPKP-SAGSDMSARKEFIV-AKYMERRFVQRGGPSEPHRLRDAIHNRDLLALLQAFAEG
HDLAKPLASPEGQ----AVSILGVSRALPPCSRTPVSWRCTW-PCAARTDRPSR------
WWTSSSRTGGCWTG----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGA-AAFAAKM-------

PF16746 // ENSGT00760000118874_5_Domain_0 (52, 288)

PR--YRGAA
LAREEILEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKLEKER--DRARVTGGIP-----GEVAQDVQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQED

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-SPGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIM-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRFWTAICNRDLLSVLEAFANG
QDFGQLLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--AQAHWASGRLDISNKTYETVASLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTLVQGCA
RRAS----------------------------GDRSEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPLEPGDPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNVPVG--ITEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------------------------------------------------------
-----ILEGDQAILQRIKK

PF16746 // ENSGT00760000118874_5_Domain_0 (80, 254)

AVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHK-----------------------------------------------------------------------------------------------------------IRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKLLIAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTNLGVLTCIQCSGVHRKLGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSHGGPKP-SPESDMGTRRDYIV-AKYVEHRFAHRC-TPEPRRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFIIQNGGHLDAKAADGNTALHYTALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAFPLHVDYSWVISTEPGFDSEEDEEE-----------------------------------------------------------------------------------------------------------------------------------------------------------KRCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------------------------------------------GESEDCPPPLPVKNSSRTVVQGCARRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PASS---SSLMSPVETGGPSQAP-PN------------------------SEEGLREPPGTSRPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSLED--GPSARQ-PL---------------PR---------------------------------------RNMPVG--VTEGDGSRTGSLPASSVQLLQD---------------------------------------------

PF00169 // ENSGT00760000118874_5_Domain_1 (244, 443)

QSLIKFFHAQHK---------------------------------------------
------------------------------------------------------------
--IRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_1_3 (443, 482)

SKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRKLGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

HRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAIKVASQASLPLVDFIIQNGGHLDAKAADGNTAL
HYTALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PA
SS---SSLMSPVETGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------VQNLNNIVSFPLDSLLKGQLKDSRMDSKKQIEKAWKDYETK
VGKMEKEK--ERARLAGVIQAEPSAAEVAEDTQKERRLFQLHMCE-YLLKASESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQNLYPFIEKLAVSLHSLHQAQEEEVKQLTQTRDALR
SILQLESKE-------------ENLSRKNSG---SGYSIHQHQGNKQYG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKSGFLYKKS
DGIRKV--WQKRKCGVKYGCLTISHS--TINRPPVKLNLLTCQVRPHAEEKKCFDLVTHN
RTYHFQAEDEQECVVWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSNAFKGEPNGGAAS-A--GSGADGSVQELT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 612)

KL
VISE------------------VKNMP-------GNK---QCCDCGA----PDPTWLSTN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLL--AVSIGNTRFNEIMEATLPTQ
DCPKP-SAGSDM------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLNSPAGAAAFA----AKMPRCRGA------A
LAREEILEGDQA

PF16746 // ENSGT00760000118874_5_Domain_0 (73, 290)

ILQRVKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVTALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRSRVTAGSP-----GETAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GTLQLEGRE-------------EHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-SPGSLG-VTGQDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTSFNEVMEAQLPSH
GGPKP-SAESDMSTRRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-TPEPQRLWTAICNRDLLSILEAFANG
QDFGQPLPGPDTQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNAGHLDAKAADGNTAL
HCAALHNQPDCLKLLLKARAPLG--AVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGISTEPGSDSEEDEDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AHARWVGGRLDISNKTYETIASLGPATPQ----------------------
------------------------------------NQSEDCPPPLPVKNSSRTMVQGCA
RHAS----------------------------GDRSEVPSLSSEPSEAPES--LGS--PA
SSS--SSLTSPVEPGSPSQAP-PS------------------------SEEGLREPPGTS
RPSLTSGTTPSE---TYPPVRF---------------SSESTRSYRRGGRSLED--GPSA
RQ-PL---------------PK--------------------------------------
-RNMPGG--FTEGDGSRTGVLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGA-AAFAAKM-------

PF16746 // ENSGT00760000118874_5_Domain_0 (52, 288)

PR--YRGAA
LAREEILEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKLEKER--DRARVTGGIP-----GEVAQDMQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQED

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELQKLTQLRDSLR
GTLQLESRE-----------GQEHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-SAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIM-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTFAF
PLHVDYSWVISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--AQAHWASGRLDISNKTYETVASLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTLVQGCA
RHAS----------------------------GDRSEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPLEPGDPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNVPVG--ITEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSP-AGAAAFAAKMPRCRGA---------A
LAREEILEGDQA

PF16746 // ENSGT00760000118874_5_Domain_0 (73, 289)

ILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALCNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEVPETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---VYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSP-AGAAAFAAKMPRCRGA---------A
LAREEILEGDQA

PF16746 // ENSGT00760000118874_5_Domain_0 (73, 289)

ILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVIGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 291)

EEALEGDQAILQRIKKAVRAIHSSGLGHV-ETEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGHLRDGRHDSKKHLEKAWKDYESK
VAKLEKER--DRARFPGGS-----HGVMSQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEEELH

ENSGT00760000118874_5_Linker_0_2 (291, 351)

KLTQLRDSLR
GMLHLESRE-------------DHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLPLLTCQVRPNPEEKRCFDLVTHN
RTYHFHAEDEQECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSNAFHGEPSG-GQWSWG--TRLDTEPHDLTNM
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

VAE------------------VKSRP-------GND---RCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNSHFNEVMEAHLPSH
GSPKP-SAESDMSSRRNYIV-AKYVEHKFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RHS-TPDPQKLRTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASHASLPIVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLRGRAPVG--AVNDAGETALDIARNRQHKECEELLEQAQAGTLAF
PLHMDYHWGHSMEHGFDSEEEEEEE-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPSKPP--AQACWGSGRLDISNKTYETVATPGPATAQ----------------------
------------------------------------SQSEDSPPPLPIKNSSRTIVLGRA
GHCS----------------------------GDRSDLPSLRSESPEALEN--RSS--PA
SSS--SSLTSSVEPGGLSQAP-SS------------------------PEEGLQEPASIS
RPGLASGTTPAE---VYLPVKF---------------SSESTRSYRRGGRSLED--SPSA
RQ-PLC--------------SR--------------------------------------
-RHIPVG--LVEGDGSKIGVLPDS-LQLLHD-----------------------------
--------------------------

------------MPEQLSVAEFLAMTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 289)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVEALGNSHLSQNSHKLST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDNLMKGQLRDGRQDSKKQLEKAWKDYEAK
VAKVEKDR--DRARVTGGSP-----VEMAQDTQRERRVFQLHMCE-YLIKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHALQQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLAQLRDSLR
GTLQLDSRE-------------EHPSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPDEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-SVGSWG-GAGLDVEPPELRKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGTSELLL--ALSIGNTRFNEVMEAQLPSQ
GCPKP-SAESDMSVRRGYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRA-TPEPQKLRTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASQASLPLVDFIIQNCGHLDAKAAEGNTAL
HHAALHDQPECLKLLLKGRAPVG--AVNEAGETALDIARRTQHKECEMLLEQAQAGTLTF
PLQLYYPWVLSTVPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCSLKPP--AQAHWASGRLDINNKTYETITSLGPAAPQ----------------------
------------------------------------SQSEDCPPPLPVKNSSRTTAQGQT
GHTS----------------------------GD---VPSLSSESSEASES--LGS--PA
SSS-PSSFTSSMEPRGPSQAQ-PN------------------------PEEGVREPPGTS
RPGLLSVPTPAE---VYPPVRF---------------SSESTRSYRRGGRNVED--SVAA
RQ-PL---------------PR--------------------------------------
-RSVPVS--VGD--GSANGFLPWYCSF---------------------------------
---PPSPLSPGLCEADHSHCRAGTAE

------------MPEQLSVAEFLAVTAEDLSSPAGAAVFA----AKIPRCRGA------A
LAREEILEGDQ

PF16746 // ENSGT00760000118874_5_Domain_0 (72, 290)

AILQRIKKAVRAIHSSGLGHV-ENEEQYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVTGGSS-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GTLQLESRE-------------ETLGRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGGGGPGPWG-GAGIEGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-SAESDMSARRDYIV-AKYVEHRFARRS-TPEPQILRTAICNRDLLLLLEAYANG
QDFGQPLPGPEGQ----APGELALHLAVRVATQASLPLVDFIIQNGERGRRDSSGHSQEE
AAQGV-----------RGAAGAG--P---GWDPHLPPARGLPLGNCPRA-----------
-------W----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------L---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQLCVAEFLAVTAEDLSSPAGAAAFA----AKMPRYRGA------A
LAREEILEGDQAILQRIKKAIRVIHSSGLGHV-ENEEQYQEAVESLGNSHLSQSSHELST
GFLNLAVFTREVAALFKNLVRPLLPCSFLPQSHKLS

PF16746 // ENSGT00760000118874_5_Domain_0 (157, 288)

GRHLTLGLDSKKQLEKAWKDYEAK
VARLEKER--DRARVPGAVP-----GELAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLQQTQEE

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELHKLTQLRDSLR
RMLQLESRE-------------EHPSRKNSG----GYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTMSHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLEEPSV-GPGSYG-GSGLDGEPQYLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNS---QCCDCRA----PDPTWLSTN
LGVLTCIHCSGVHRELGVRFSRMQSLSLDLLCPTELLL--ALNIGNMRFNEVMEAQLPSH
GGPKP-SAESDMSARRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 705)

RS-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDGQ-----APELALHLAVRVANQASLPTVDFIIQ

PF13857 // ENSGT00760000118874_5_Domain_5 (705, 758)

NCGHLDAKATDGNTAL
HFAALHGQPDCLKLLLKGRAPVG--TVNEAGETALDIARKKQHKECEELLEQAQEGTLAF
PLHVDYPWGLSTEPGSDSEEEEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCSLKPP--AHACRARGKLDITNKTYETITSLEPAAPQ----------------------
------------------------------------SQNEDSPPPLPIKISSRTMVPGHL
GHAS----------------------------GDRSGIPSLSSEPSEASES--RDS--PA
TSS--SILTSPVEPGGPSQSL-PG------------------------LEEGLQESPGTS
QSILASGTTPAE---VHLPIRF---------------SSESTRSYRRGGRSPED--CPSA
QQ-PL---------------PR--------------------------------------
-KNIPVGAAFIEGDGSKTGVLAPSSLQLFQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMSRCRGA------A
LAREEILEGDQAILQRIKKAVRVIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAK
IARLEKER--DRARMTGGSP-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
GFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEELQKLTQLRDSLR
GTLQLESRE-------------ENLSRKNSG---GGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSG-SPVPWG-CTGLDGEPQDVT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LISE------------------VKSRP-------GNR---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNARFNEVMEAQLPSH
GGPKP-SAESDMSGRRDYIV-AKYVEHRFARRS-TLE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQRLWTAICNRDLLSVLEAFANG
QDFRQPLSGPDGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAIRVANQASLPLVDFIIQNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNSAV
HYAALHNQPDCLKLLLKGRVSVG--TVNEAGETALDIARKKQHKECEELLEQAQAGALAF
PLHVDYSWGISTEPGSDSEEDEDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AQVRWASGRMDISNKTYETVTSLEPAASQ----------------------
------------------------------------TQSEDCPPPLPVKNPSRTMVQERA
GHTR----------------------------GDRSEVPGLSSEPPEVPEN--LGS--PA
SS---SSLTSPVELAGANQSP-HS------------------------SEEGLWEPPGTS
RPSLTSGTTPTE---TYLPVRF---------------SSESTRSYRRGGRSLED--CPSA
RQ-PL---------------PR--------------------------------------
-RNMQVG--FTEGEGSRTGVLPANSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 290)

EEMLEGDQAILQRIKKAVRAIQSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDTLLKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVIGGST-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGLKAAQSLSPFIEKLAVSVHTLRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GTLQLESRE-------------ESLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGS-GSGPWG-AAGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDWA------GPTPLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLP--
---KP-SAESDMSTRRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPEGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 770)

LHLAVRVANQASLPLVDFIIQNGGHLDAKAADGNSAL
HCAALYNQLDCLKLLLKGRASVA--TVNDAGETALDIARKKQHKECENLLEQAQAGTLTF
PLHLDYPWGISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCALKPP--AQARWTSGRLDISNKTYETITSLVPAASK----------------------
------------------------------------SQSEDRPPPLPVKNPSRPMAHGRV
GHAS----------------------------GDRSEIPSLSSESLGASEN--LSS--PA
SSS--SSLTSPVEPGGPNETL-PS------------------------SEEGPCEPAGPS
RPSLTSGTSPAE---MYPPVRF---------------RLVKARSKHLLISWLQSPSAVLR
RY-QF---------------SS--------------------------------------
-FSPQVG--FPEGDGSRTGVLLPSSVQLLQD-----------------------------
--------------------------

------------MPKQFSVAEFLAVTVEDLSSPAGAAAFV----AKMPRCRGA------V
LAREEILEGDQAILQRIKKAVRMIHSSGLGHV-ENEEQYQEAVESLGNSHLSQNSHELST
GFLNLSVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQXXXXXXXXXXXXXXXX
XTRLEKER--DRARMSGGSP-----GELAHDTQRERRVFQLHMCE-YLLKAKESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAVSVHALRQAQEEELQNLTQLRDSLR
GTLQLESRE-------------ENLNRKNSG---GGYSIPQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
DGIRRV--WQKRKCGIKYGCLTISHS--TINRPPVKLTLLTCQVRPNLEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSS-SPGSLG-HAGLQGEPQDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAE------------------VKNRP-------GNN---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGSSELLL--ALNIGNTCFNEIMEAQLPSH
SGPKP-SAESNMSARRDYIV-AKYVEHRFARRS-TLE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQRLQMAICNQDLLSVLEAFANG
QDFRQPLLEPEGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAIRVANQTSLPLVDFIIQNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNSAL
HCAALYNQPDCLKLLLKGRASVG--SVN

ENSGT00760000118874_5_Linker_5_6 (749, 750)

D

PF00023 // ENSGT00760000118874_5_Domain_6 (750, 770)

SGETALDIARKKQHKECEELLEQAQAGTLAF
PLHLDYSWEISTEPGSDSGEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
LCPLKPP--TLAHWTNVRLDISNKTYETITSLAPTAPQ----------------------
------------------------------------SQSEDFPPPLPVKNPSRSVVQERA
GHGS----------------------------RDWLEAPSLSLEPFGVPEN--LSS--PG
SSS--SSLMSPVEPGGPSKTL-PG------------------------SEEGPRESPGPS
KPSLISGTTLAE---TYHPVRS---------------SSESTRSYRRGGRSLED--SSSS
RQ-PL---------------LK--------------------------------------
-RNMPVG--ITEGDSSRGGSPPSS-LQLQD------------------------------
--------------------------

------------------------------------------------------------
-----ILEGDQAILQRIKKA

PF16746 // ENSGT00760000118874_5_Domain_0 (81, 289)

VRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
VARLEKER--DRARVTAWSP-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTRLRDSLR
GTLQLESRE-------------DHLGRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSKDEAWSSAFLGEPGG-RPGSWA-GAGQDGEPQDLTKL
LIAE------------------VKXXX-------XXX---XXX-----------------
-------------XXXXXXXXXMQSLTLDLLGPSELLL--ALNIGNTSFNEVMEAQLPSH
GGPKP-SAESDMVSRRDYIV-AKYVEHRFARRS-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDTQ----VPGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL
HCAALHNQPDCLKLLLKGRASLS--TVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGNSMEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPLKLQ--AQARWATGRLDISNKIYETTASLGAATPQ----------------------
------------------------------------SQSEDCPPPLPAKTCARAVIQGST
RHTS----------------------------GDRSEVPNLSSEPPEVPES--LSS--PV
SSS--SSLMSPMEAGGPSQGP-PG------------------------SEEGLREPPGIS
RPSLTPGTTLSE---MYLPVRF---------------SSESTRSYRRGGRSLED--GPSA
RQ-PP---------------PR--------------------------------------
-RNVPVG--FTEGDGSRSRVLPASSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAREEVLEGDQAILQRIKKAVRAIHSSGLGHV-ETEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDNLMKGHLRDGRHDSKKHLEKAWKDYETK
VVKLKRER--ERERIPGLYS-----ETLSQNTQEEKTAFQLHAWK-KLRKATKATRRQGP
GFGPSSRKKDQKRHHSFTQFWGASQALYPLVSGNSATLHSYPQSHTMALHLYWGWRDGLQ
RYNHLVSRD-------------PMPSSKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MVNRPPVKLALLTCQVRPNPEDKRCFDLVTHN
RTYHFHAEDELECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFHGEPSG-GQWSWG--TRLDTEPHDLTNM
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

VAE------------------VKSRP-------GND---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRYSRIQSLTLDLLGPSELLL--ALNIGNSHFNEVMEAHLPSH
GSPKP-SAESDMSSRRNYIV-AKYVEHKFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-TPEPQKLRTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASQASLPIVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLKGRAPMG--AVNNAGETALDVARNKQHKDCEELLEQAQAGTLAF
PLPMDYHWGHSMDHGFDSEEEEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPVKPP--AQACWSSGRLDISNRTYETVANPGPTSSQ----------------------
------------------------------------SQSEDSPPPLPIKNSSRTILLGRA
GDSS----------------------------RDRSDIPSLRSESPEASEN--RSS--PA
SSS--SSFTSSVEPGGLSQAL-PS------------------------PEESLQEPPGTS
RPGLASGTTPAE---VYLPVRF---------------SSESTRSYRRGGRNLED--GPAA
RL-PLC---------------R--------------------------------------
-RNIPVG--LMEGDGSKIGVLPASSLQLSHD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAREEMLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDTLLKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVIGGST-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGLKAAQSLSPFIEKLAVSVHTLRQAQEEELQKLTQLRDSLR
GTLQLESRE-------------ESLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGS-GPGPWG-AAGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-SAESDMSARRDYIV-AKYVEHRFARRS-TPEPQRLCTAICNRDLLSVLEAFANG
QDFGQPLPGPEGQ----APGELALHLAVRVANQASLPLVDFIIQNGGHLDAKAA

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 743)

DGNSAL
HCAVFYNQLDCLKLLLKGRASVA--TVNEAGETALDIARRKQHKECENLLEQAQAGTLTF
PLHLDYAWGISTEPGSDSEEDEEEK-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------Q
RCALKPP--AQARWTSGRLDISNKTYETITSLGPAAPK----------------------
------------------------------------SQSEDCPPPLPVKNLSRTMAQGRV
GHAS----------------------------GDRSEIPSLSSESLGASEN--LSS--PA
SSS--SSLTSPVEPGGPNETL-PS------------------------SEEGPCEPQGPS
RPSLTSGISPAE---MYPPVRF---------------SSESTRSYRRGRSLEE---CRSA
RQ-PV---------------PG--------------------------------------
-RNVMVG--FPEGDGSRTGVLLPSSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSAAGAAAFA----ARMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 290)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAR
VARLEKER--ERARVTGGLP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GSLQLESRE-----------GQEHLRRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECDAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGG-GPGSAA-GSGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGTKP-SAESDMSTRRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 703)

RS-ACEPQKLRAAIYNRDLLSVLEAFASG
QDFGQPLPGPDGQ----APGELALHLAVRVANQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 757)

IQNGGHLDDKAANGNTAL
HYAALHGQPDCLKLLLKGRASVG--TVNEAGETALDIVRKKQHKECEELLEQAQAGTLTF
PLHLDYSWGISMEPGSDSEDDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPPRPP--AQARWASGRLDISNKTYETIGSLGPATLQ----------------------
------------------------------------SQSEDCPPPLPVKASSRTMVHGRT
AHAS----------------------------GDRSEVSSLSSEPPEASEG--LGS--PA
SSS--SSLTSPVEPGGPSQAL-PT------------------------SEEGLREPPGTS
RAGLTSGTTPVD---GYLPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PL---------------PR--------------------------------------
-RNTPIG--FTEGEGSKTSVLPASSL----------------------------------
--------------------------

---------MKGFGEHVSLAPSLGI-------------------TEMPMF----------
PLLAFVLEGDQAILQR

PF16746 // ENSGT00760000118874_5_Domain_0 (77, 290)

IKKAVRAIHSSGLGHV-DNEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSRKQLEKAWKDYEAK
VARLEKER--ERARVTGGLP-----GEAAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GSLQLESRE-------------EHLRRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 434)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLFTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHEC

ENSGT00760000118874_5_Linker_2_3 (434, 525)

EALEGKGR---------------------------------------
-----------------------------------AC---ALQL

PF01412 // ENSGT00760000118874_5_Domain_3 (525, 632)

CSS----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGTKP-SAESDMSTRRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_4 (632, 644)

RS-ACEAQKLQA

PF12796 // ENSGT00760000118874_5_Domain_4 (644, 742)

AIYNRDLLSVLEAFASG
QDFGQPLPGLDGQ----APGELALHLAVRVANQASLPLVDFIIQNGGHLDAKAADGNTAL
HCAALHGQSDCLKLLLKGRASVG--TVNEAGETALDIVRKKQHKECEELLEQAQAGTLTFPLHLDYAWGISVEPGTDSEEDEEE-----------------------------------------------------------------------------------------------------------------------------------------------------------KHCSLKPP--AQARWASRRLDISNKTYETIGSLGPATLQ----------------------------------------------------------SQSEDCPPPLPVKASSRTVVQGRVDYAT----------------------------GDRSEVSSLSSEPPEASEG--LGS--PASSS--SSLTSPVESGGPSQTL-PS------------------------SEEGLQEPPGTSRATVTSGTTPAE---VHLPVRF---------------SSESTRSYRRGARSLED--GPSARQ-PL---------------PR--------------------------

PF12796 // ENSGT00760000118874_5_Domain_5 (644, 742)

AIYNRDLLSVLEAFASGQDFGQPLPGLDGQ----APGELALHLAVRVANQASLPLVDFIIQNGGHLDAKAADGNTALHCAALHGQSDCLKLLLKGRASVG--TVNEAGETALDIVRKKQHKECEELLEQAQAGTLTF
PLHLDYAWGISVEPGTDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCSLKPP--AQARWASRRLDISNKTYETIGSLGPATLQ----------------------
------------------------------------SQSEDCPPPLPVKASSRTVVQGRV
DYAT----------------------------GDRSEVSSLSSEPPEASEG--LGS--PA
SSS--SSLTSPVESGGPSQTL-PS------------------------SEEGLQEPPGTS
RATVTSGTTPAE---VHLPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PL---------------PR--------------------------------------
-RNTPVG--FTEGDGSKTGVLPANSL----------------------------------
--------------------------

-------------------------------DP-SASASQSAGINR-------------C
EPLRPILEGDQAILQRIKKA

PF16746 // ENSGT00760000118874_5_Domain_0 (81, 289)

VRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAVSVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-----------GQEHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALCNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEVLETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---VYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

-------------KKRCRQKAFLG-------RASGHDLVL----PSVVFCIGRKLRPRTR
VVYLCVLEGDQAILQRIKKSVRAIHSSGLGHV-ENEEHYREAVEALGNSHLS

PF16746 // ENSGT00760000118874_5_Domain_0 (113, 289)

QNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLESLMKGQLRDGRHDSKKHLEKAWKDYETK
VAKLEKER--DRARVTGGGH-----GEMSQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHELRQTQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GMLHLESRE-------------EHPNRKNSG---VGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEEKTCFDLVTHN
RTYHFHAEDELECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSSAFNGEPSG-GPWSWG-GTRLDAEPQDLTKM

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

LIAE------------------VKSRP-------GNG---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLSSSELLL--ALNIGNSRFNEVMEAHLPCH
RSPKP-SAESDMSSRRNYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

QS-TPEPQKLWTAICNRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAIRVASQASLPLVDFLIQNGGHLDAKAADGNTAL
HLAALHGQLDCLKLLLKGRAPVG--TVNDAGETALDIARKKCHKECEELLEQAQAGTLTF
PLHMDYPWGHSMEHGFDSEEDEDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPVKPP--AKACWSSGRLDISNKTYETIASPGPATSQ----------------------
------------------------------------SQNENSPPPLPVKNSSRTILPGRA
GHSS----------------------------GDCSDTPSLRSESPEASEN--PSS--PA
SSS--SSLTSFVEAGGLSQAP-SS------------------------PEEGLQELPGTS
RPGPAPGTTPIE---VYHPVKF---------------SSESTRSYRRGGRSLED--SPCA
RQ-PL---------------SR--------------------------------------
-RNILVC--LTEGDGSKTGVQPASSLQLLHD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTTEDLSSPTGAA-AFAAKMSRC---------RGAA
LAREEILEGDQAILQ

PF16746 // ENSGT00760000118874_5_Domain_0 (76, 289)

RIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKVEKER--DRARVTGGIH-----GEVTQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLDSRE-------------EHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFHAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-AAGQDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNVGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRREYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQHLGEAPEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDARAVDGSTAV
HYAALYNQPDCIKLLLKGRALLG--IVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGISTEPGSESEEDEDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKPP--AQAHWASGRLDISNKTYETVASLGAATLQ----------------------
------------------------------------GESEDCPPPLPIKNSSRTVVQGCA
RHAS----------------------------GDHSEVPSLSSDAPEAPES--LGS--PA
SSS-SSSLMSPTDPGGPSQAP-PS------------------------SEDGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSLED--GSSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FTEGDGSRTGTLPASSMQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----TKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 290)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRHDSKKHLEKAWKDYETK
VAKLEKER--DRARVTGGSH-----GELSHDTQRERRVFQLHMCE-YLVKAGESQVRQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHELRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GMLHLESRE-------------EHPNRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEDKRCFDLVTHN
RTYHFHAEDELECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSSAFNGEPSGGH-WSWG-SARLDAEPQDLTKM

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

LIAE------------------VKSRP-------GNG---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPCELLL--ALNIGNSHFNEVMEARLPSH
GSPKP-SAESDMSSRRNYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

QS-TPEPQRLWTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVRVASQASLPLVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLKGRAPVG--AVNDAGETALDIAKKKQHKECEELLEQAQAGTLTF
PLHMDYPWGHSLEHGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPVKPP--AQACWGSGRLDISNKTYETVASPGPAPSQ----------------------
------------------------------------SQSEDSPPPLPAKNSSRTTLPGRA
GHCS----------------------------GDRSDTPSLRSESPEVSEN--PNS--PA
SSS--SSLTSSVEPGGLSLAP-PS------------------------PEEGLQEPPGTC
RPGLASGTTPTE---VHLPVKF---------------SSESTRSYRRGGRSLEE--SPSA
RQ-PL---------------SR--------------------------------------
-RNILVG--LTEGDGSKPGVLPAGSLQLLHD-----------------------------
--------------------------

------------------------------------------------------------
-----VLEGDQAILQRIKKXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAR
VARLEKER--ERARVTGGGP-----GEVAQDAQRERRVFQLHMCE-YLLKAGESQVKQGP
DFLQSLIKFFHAQHNSR--DW--AAQLSPFIEKLAASVHALRQAQEEELQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---GGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 437)

TEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXX------------------XXXXX-------XXXX--XXXXXXX----XXXXXXXXX
XXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX-XXXXXXSIRRDYIV-AKYVGHRFARRS-TPEPQRLRTAIYNKDLLSVLEAFASG
QDFGQPLPGPEGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAVKVANQASLPLVDFIIQNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNTAL
HYAALCNQPDCLRLLLKGRASTG--TVNEAGETALDIARQKPHKECEELLEQAQAGTLVF
PLHVDYSWVVSTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AQARWAPGRVNLNNKTYETVASLGLATPQ----------------------
------------------------------------SQSEDCPPPLPVKNSSRAVSQGRA
GPAS----------------------------GDRPDGPSLSPEAPETPEG--LDS--PA
SSS-SSSLTSPTEPGGLQAPS--S------------------------SEEGLRQPLGTS
RPSP--GPTPAE---MYPPVRF---------------SSESTRSYRRGARSLED--GPSA
RQPP----------------SR--------------------------------------
-RNVPTG--VTEGDVSRTGALPASSVQLLQD-----------------------------
--------------------------

MPPAPFPALGAWIPPHTSAQQSCSLSRGQLGWG--SG-SR----AWLISSVCF------L
SLLLQNLDGDQAVLQRIRKYVKAIHISGLAHV-ENEEQYSEALENFGNNHLSQNNHELST
GFLNLAVFTREVTALFKNLVQNLNNIVSFPMDSLLKGQLKDGRLDSKKQIEKAWKDYETK
VGKMEKEK--ERARLAGAAQAEPAAAEVAEDVQRERRLLQLHMCE-YLLKASESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQNLSPFVEKLALSLHRLRQAQEEQLKQLAQTRDALR
SVLQLDSREVF---------FQENMSRKNSG---SGYSIHQHQGNKQYGM

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKSGFLYKKS
DGIRKV--WQKRKCGVKYGCLTISHS--TINRPPVKLNLLTCQVRPHTEEKKCFDLVTHN
RTYHFQAEDEQECVVWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSNAFRGDGGG-------------GSMQELTRL

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

VISE------------------VKNMP-------GNK---QCCDCGA----PDPTWLSTN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLL--AVSIGNTRFNEIMEATLPTQ
DCPKP-SASSDMAARKEYIM-AKYMERRFAHRSGQDNPHGLWEAIRDRDLLALLKAFVEG
HDLTKPLASPDGQ----DAGELPLHVAVRHADRSSLPLVDFIIQNGGTLDQVTQ

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 740)

DGNTAL
HYGALYNQPNCLKLLLKGKATFT--TVNAAGETALDVARRLKYSECEELLEQAQAGKLSL
QIHVDYDWEPPSEFPYDSEDELEDKVSPLQ------------RSFNGTSALAASPLPT--
------------------------------------------------------------
------------------------------------------------------------
--------CPQSRWSCVGMDITNKTYESILVPLPPPPPPPPPPPPPPPPPPPPPPPPPPP
PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPLPLKNPTRGSSRPKA
SLSPSGEPECGATAGLCLPPETTAIVPIVCVPPERPELPRQASEPPCPGPAEALAARSLP
CAGSTAAPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP
PPPPPPPPPPPHNDS----DFLEKHQDPLLQVIIFTPSSESTRSYRRVSAMVGRMGVAGS
PQSPGGPEDPPLGKVPPVPMPRRFAPAKGRQK

PF07653 // ENSGT00760000118874_5_Domain_7 (1293, 1346)

RVKAVADCKGDKARELTFSKGEVIVVTR
EEDEQIWVGFIEGDGSRTGVFPASFVHLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGATAFA----AKMSRCRGAALA----
--REEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXVQNLNNIVSFPLDSMLKGQLRDGRQDSKKQLEKAWKDYETK
MARLEKER--ERAKVTGGSP-----SEVAQDTQRERHVFQLHMCE-YLLKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAATVHTLRQAQEEELQKLTQLRDSLR
GTLQLENRE-------------ENLSRKNSG---GGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQVEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSS-CPAPWGGATGLDGEPQDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAE------------------VKSRP-------GNG---QCCDCGA----TDPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSN
GGAKP-SAESDMSTRRDYIVVAKYVEHRFARRA-XXX

ENSGT00760000118874_5_Linker_3_4 (638, 679)

XXXXXXXXXXXXXXXXXXX---X
XXXXXXXXXXXXXXXXXA

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAIRVADQTSLPLVDFIIQNGGHPDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNSAL
HCAALYNQLDCLKLLLKGRASAG--TVNEAGETALDIARKKQHKECELLLEQAQAGTLAF
PLHLDYSWGVSPEAGSDSEEEEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RC-PLPP--TQTRWASGRLDISNKTYETIASVGPVTPQ----------------------
------------------------------------SQNENCPPPLPVKNPSRTVIPARA
GYGS----------------------------GDRSEAPTLSSEPHGPPES--LAS--SA
SSS--SSLTSPLEHGGPSQTL-PG------------------------SEEGLWESPGLS
RPGLMSGTAPVX---XXXXXXX---------------XSESTRSYRRGARNLED--SPSA
RQPL----------------LR--------------------------------------
-RNTPAG--FTDGDGSRTGVLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGA-AAFAAKM-------

PF16746 // ENSGT00760000118874_5_Domain_0 (52, 288)

PR--YRGAA
LAREEILEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLGVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKLEKER--DRARVTGGIP-----GEVAQDMQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQED

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELQKLTQLRDSLR
GTLQLESRE-----------GQEHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-SAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIM-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQTSLPLVDFIIQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTFAF
PLHVDYSWVISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--AQAHWASGRLDISNKTYETVASLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTLVQGCA
RHAS----------------------------GDRSEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPLEPGDPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-LL---------------PR--------------------------------------
-RNVPVG--ITEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

-------------------------------------------MPRCRGA---------A
LAREEILEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEELQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-VAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNASFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFARRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFIIQNGGHLDAKAA

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 740)

DGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTALE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSP-AGAAAFAAKMPRCRGA---------A
LAREEILEGDQA

PF16746 // ENSGT00760000118874_5_Domain_0 (73, 289)

ILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLLVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------------------------------------------------------
----QVLEGDQALLQRVKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVTGGSP-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEELQKLTQLRDSLR
GTLQLESRE-------------ENLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 438)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWV

ENSGT00760000118874_5_Linker_2_3 (438, 483)

SV-QNSKDEALSSAFLGEPGV-GPGPWG-GAGWTGSPKDLTKL
LI

PF01412 // ENSGT00760000118874_5_Domain_3 (483, 632)

AE------------------C-------------------------------------
---------S-GHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-SAESDMSARRDYIV-AKYVEHRFARRS-TPEPQRLWMAICNRDLLSVLEAFANG
QDFGQLLPGPEGQ----APGELALHLAVRVASQASLPLVDFIIQNGGHLDAKAA

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 738)

DGNSAL
HYAALYNQPDCLKLLLKGRAAAG--SVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYPWGISPEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCSLKPP--AQVRWASGRLDISNKTYETFASLGPA-PQ----------------------
------------------------------------SQSEDCPPPLPVKNPSRTVVQGRA
GHAS----------------------------GDRSEVPSLSSEAPGASES--LSS--PA
SSS--SSLTSPVEPGGPSQSP-HG------------------------SEEGLWEPSGAS
RPSLTSGTTPAE---MYPPVRF---------------SSESTRSYRRGARSPED--CPTA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FTEGEGSRTGVLPASSVQLLQD-----------------------------
--------------------------

--------------------------------------------------RGF------V
PLLSQSLDGDQAVLQRIRKYVKAIHVSGLTHV-DNEEQYSEALENFGNNHLSQNNHELST
GFLNLAVFTREVTALFKNLVQNLNNIVSFPLDSLLKGQLKDGRLDSKKQIEKAWKDYETK
LELGRLPLCSSPKTFRGGGR-EEAGIQVRTGPGPHHLTRCLLPPQ-YLLKASESQMKQGP
DFLQSLIKFFHAQHSFFQDGWKAAQNLYPFIEKLAVSLHALHQAQEEEVKQLAQTRDSLR
SILQLDTKE-------------ENLSRKNSG---SGYSIHQHQGNKQYG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 449)

TEKSGFLYKKS
DGIRKV--WQKRKCGVKYGCLTISHRNTQINRPPVKLNLLTCQVRPHAEEKKCFDLGRTN
PARRWLPRAPD--KRWQQGV----GRAM

ENSGT00760000118874_5_Linker_2_3 (449, 523)

RSDFLAKK-------------------KXGAF
PTRL------------------CSPCP-------GGF---RC

PF01412 // ENSGT00760000118874_5_Domain_3 (523, 660)

CRTATPLRPADPTWLSTN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLL--AVSVGNTRFNEIMEATLPTQ
DCPKPSASS-D----------------------MCPPPHRLWDAIRTRDLLALLQAFAEG
HDXRSSLGGVLGS----L-GSVVLSPSCRQDAAGVTPLVAAAAAHRGTLDRVTQ

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 740)

DGNTAL
HYGALYNQPNCLKLLLKGKAAFT--AG---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAREEALEGDQVILQRIK

PF16746 // ENSGT00760000118874_5_Domain_0 (79, 288)

KAVRAIHSSGLGHV-ETEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGHLRDGRHDSKKHLEKAWKDYETK
VAKLEKER--DRARFPGGSH----HGVMSQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEE

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELHKLTQLRDSLR
GMLHLESRE-------------DHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRKV--WQKRKCGVKYGCLTISHS--MINRPPVKLALLTCQVRPNPEEKRCFDLVTHN
RTYHFHAEDEQECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFHGEPSG-GQWSWG--TRLDTEPHDLTNM
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

VAE------------------VKSRP-------GND---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNSHFNEVMEARLPSH
GSPKP-SAESDMSCRRNYIV-AKYVEHKFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RSS-TPDPQKLRTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASHASLPIVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLRGRAPVG--AVNDAGETALDLARNRQHKECEELLEQAQAGTLAF
PLHMDYHWGHSMEHGFDSEEEEEEE-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCSSKPP--AQACWGSGRLDISNKTYETVATPGPATAQ----------------------
------------------------------------SQSEDSPPPLPVKNSSRTIVLGRA
GHSS----------------------------GDRSDLPSLRSESPEALEN--RSS--PA
SSS--SSLTSSVEAGGLSQAP-FS------------------------PEEGLQEPASIS
RP---SGTTPAE---VYLPVKF---------------SSESTRSYRRGGRSLED--SPSA
RQ-PPC--------------R---------------------------------------
-RNIPAG--LMEGDGSKIGVLPASSLQLLHD-----------------------------
--------------------------

------------MPEQISVSEFLAVTSEDLNSPAAST-FS----SKMQKCRGA------V
AALEESLDGDQAILQRIRKYVKAIHSSGLAHV-ENEEQYSESLENFGNNHLSQNNHELST
GFLNLAVFTREVTALLKNMVQNLNNIVSFPLDSLLKGQLKDGRLDYKKQIEKAWKDYETK
VAKMEKER--ERARAAGVIQVEPSPADIAEETQKERRMFQLQMCE-YLLKANESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQNLYPFIEKLSASLHVLHQAQEEEVKELTQIRDSLR
GILQLENKEGVGEIQGGYTPPWENLHRKNSG---SGYSIHQHQGNKQYGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKSGFLSKKS
DGLGAKPDLESAKCG---SCLTISHS--TINRPPVKLNLLTCQVRPHPEEKKCFDLVTHN
RTYHFQAEDEQECVVWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 502)

SKDEALSNAFKGDPSSCVAS-A--GGVTDGGLQELTRL
VMGE-----------------

PF01412 // ENSGT00760000118874_5_Domain_3 (502, 632)

-VKGMP-------GNR---QCCDCGA----PDPTWLSIN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLL--AVSIGNVRFNEISSLGMGSS
SLPPT-----RRSARKEYIV-AKYMERKYVQKDGRDESHRLWEAIRSRDLLALLQAFAEG
HDLAKPLASPDSQ----DQGELALHLAVRYADKSSLPLVDFIIQNGGNLDRATQ

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 748)

DGNTAL
HYSAQYNQPNCLKLLLKGKAATN--TVNAAGETALDVARRHKHTECEELLEQAQAGKLNL
QVPLDYDWEVPQEYTYDSEDDQEEKVPLPSVACMCPWSPLGQGSLRGRGSLAVSALLMPP
ATQAFPSGLFAWQAEISGLAQQCAGPSAEKEPCSWMGGKAKGWRSLASGSRESIKPSGGA
MSLNAWWAPSPRPLQPQASLPSSPRTGGAALAWTSATRPTRPSWFPPGPSGSCKAASTSS
PTTGQPALFPQNRWSCSGMDISNKTYETILVPSRPVQRRSH-------------------
--------------------------------------SEEIPPPLPVKNPTRGGSRTKP
GQSP----------------------------ADRPELPRQASEPQASTLSEAPALRHLS
TSSAPSTLDSSA-----------------------------------------------S
RPLSTSRSPPEARRT----VCWETHAEAESGSA---------------------ISLPSS
EELPSSKAPSSVPNAAPVPMPRRFAPAKGRQKR

PF07653 // ENSGT00760000118874_5_Domain_8 (1294, 1346)

VMALMDCKGERARELSFSKGEVIVVTR
EEDEQSWVGFIEGDGSRTGVFPASFVHLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSAAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 289)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAR
VARLEKER--ERARVTGGVP-----GEGAQDTQRERRIFQLQMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGLKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLSQLRDSLR
GSLQLESRE-------------EHLRRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGG-GPGSRA-GSGLDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSLP-------GNG---QCCDCAA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLLAN
GGTKP-SAESDMSTRRDYVV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 703)

RT-AYEPQKLQAAIYNRDLLSVLEAFASG
QDFGQPLPGPDGQ----APGELALHLAIRVANQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 757)

IQNGGHLDNKAANGNTAL
HYAALHGQPDCLKLLLKGRASVG--IVNEAGETALDIVRKKQHKECEELLEQAQAGTLTF
PLHLDYSWGISMEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCTLKPP--AQARWASGRLDISNKTYEPIGSLGTAILQ----------------------
------------------------------------GQSEDCPPPLPVKASSRTMIQGRV
SHAS----------------------------ADRSEVSSLSSEPPEASEG--F-S--PA
SSS--SSLTSPVEPWGPSQAL-SS------------------------SEEGLREPAGTF
RAGLTSGTTPAD---VYLPVRF---------------SSESTRSYRRGARSLED--GPSV
RQ-PL---------------SR--------------------------------------
-KNMPVG--FTEGDGSKTGVLPASSLFLQDL-----------------------------
--------------------------

------------VPEQLSVAEYLAVTAKDLSSPAGATAFT----AKMPWCWGGVAP----
--AQEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXVTALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLERAWKDYEAK
ILRLEKER--DRARAAAGSF-----GEVAQDTQRERRTFQLHMCE-YLLKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLAPFIEKLAASVHTLRQAQEEELQKLAQLRDSLR
GTLQLESKE-------------ESLGRKNSG---GGYNIQQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVKPHPEEKKCFDLVTHN
RIYHFQTEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGETGG-GPGPCGGGAGQDGE----T

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 631)

RL
LLAE------------------VKSRP-------GNG---QCCDCGA----PDPTWLSTN
LGVLTCIRCSGVHRELGVRFSRMHSLTLDLLGPSELLI--ALNMGNARFNEVMEAQLPSH
GCPKP-SAESDXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX--XXXXXXXXXXX---X
XXXXXXXXXXXXXXXXXATGGLALHWAVRVANQASLPLVDFIIQNGXXXXXXXX

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNTAL
HCAAFYNQPDCLKLLLKGRASPG--TVNEAGESALDVARRKQHKECEELLEQAQAGTLTF
PLHVDYPWGIPAEPASDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RYPPKPP--AQACWGSGRLDISNRTYETLASLGPAALW----------------------
------------------------------------S-SNDCPPPLPVKNPSRVLGQARV
GPTS----------------------------GDCPEVPSLSLEPPGTPES--LDS--PA
SSS--SSLTSPLEPRAPSQAP-PS------------------------WEDHLQEPSSTT
LPSLLSGTTPGE---MYPPVRF---------------SSESTRSYRRGARRLEE--GTSA
QQLL----------------SG--------------------------------------
-RNVPAG--CPEEDGSRPGLLPGSSVQLWQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 288)

EEALEGDQAILQRIKKAVRAIHSSGLGHV-ETEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGHLRDGRHDSKKHLEKAWKDYESK
VAKLEKER--DRARFPGGS-----HGVMSQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEE

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELHKLTQLRDSLR
GMLHLESRE-------------DHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLPLLTCQVRPNPEEKRCFDLVTHN
RTYHFHAEDEQECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSNAFHGEPSG-GQWSWG--TRLDTEPHDLTNM
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

VAE------------------VKSRP-------GND---RCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNSHFNEVMEAHLPSH
GSPKP-SAESDMSSRRNYIV-AKYVEHKFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RHS-TPDPQKLRTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAIRVASHASLPIVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLRGRAPVG--AVNDAGETALDIARNRQHKECEELLEQAQAGTLAF
PLHMDYHWGHSMEHGFDSEEEEEEE-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPSKPP--AQACWGSVRLDISNKTYETVATPGPATTQ----------------------
------------------------------------SQSEDSPPPLPIKNSSRTIVLGRA
GHCS----------------------------GDRSDLPSLRSESPEALEN--RSS--PA
SSS--SSLTSSVEPGGLSQAP-SS------------------------PEEGLQESASIS
RPGLASGTTSAE---VYLPVKF---------------SSESTRSYRRGGRSLED--SPSA
RQ-PLC--------------SR--------------------------------------
-RHIPVG--LVEGDGSKIGVLPDS-LQLLHD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 288)

EEALEGDQAILQRIKKAVRAIHSSGLGHV-ETEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGHLRDGRHDSKKHLEKAWKDYESK
VAKLEKER--DRARFPGGS-----HGVMSQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEE

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELHKLTQLRDSLR
GMLHLESRE-------------DHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLPLLTCQVRPNPEERRCFDLVTHN
RTYHFHAEDEQECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSNAFHGEPSG-GQWSWG--TRLDTEPHDLTNM
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

VAE------------------VKSRP-------GND---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNSHFNEVMEAHLPSH
GSPKP-SAESDMSSRRNYIV-AKYVEHKFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RHS-TPDPQKLRTAICNRDLLSILEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASHASLSIVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLRGRAPVG--AVNDAGETALDIARNRQHKECEELLEQAQAGTLAF
PLHMDYHWGHSMEHGFDSEEEEEEE-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPSKPP--AQACWGSGRLDISNKTYETVATPGPATAQ----------------------
------------------------------------SQSEDSPPPLPIKNSSRTIVLGRA
GHCS----------------------------GDRSDLPSLRSESPEALEN--RSS--PA
SSS--SSLTSSVEPGGLSQAP-SS------------------------PEEGLQEPAGIS
RPGLASGTTPAE---VYLPVRF---------------SSESTRSYRRGGRSLED--SPSA
RQ-PLC--------------SR--------------------------------------
-RNIPVG--LVEGDGSKIGVLPDS-LQLLHD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPLGAAAFA----AKMPRCRGA------A
LAREEXXXXXXXXXXXXXXXXXXXXXXXXXHV-ENEDQYREAVEALGNSHLSQSSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSRKHLEKAWKDYETK
VTRLEKER--DRTRMTGGSP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHXXXXXXXXXXXXXXXXXXXXXXXXXXLRQAQEEELQKLSQLRDSLR
GTLQLENRE-------------EHLNRKNSG---GGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEEKKCFDLVTHS
RTYHFQAEDEQECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSG-SPRPWA-GAGPDTEPQELT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAK------------------VKSQP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFTRMQSLTLDLLGPAELLLA---LIGNTRFNEIMDAQLPSH
HGPKP-TAESDMSTRRDYIV-AKYVEHKFARRS-TPD

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQKLRTAICNRDLLAVLEAFASG
QDFGQPLPGPEGQ----M

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGEFALHLAVQVASQASLPLVEFIIHNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNTAL
HYAALANQPDCLKLLLKGRAVAG--TVN

ENSGT00760000118874_5_Linker_5_6 (749, 750)

E

PF00023 // ENSGT00760000118874_5_Domain_6 (750, 770)

AGETALDIARRKQHKECEELLEQAQAGTLSF
PLHVDYSWGIPAEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCSLKPS--AQARWTSGRLDISNKTYEPFPSLGPALPQ----------------------
------------------------------------SQSDTCPPPLPAKHSSRSVGQGRA
GPGS----------------------------GDHSEAPNLNLEPPEAPEN--LGS--PA
SSS--SSLTSLVEIGGLSAAS--T------------------------SSENVREAPGSS
RTSVTSGTSPAE---PHLPVRF---------------SSESTRSYRRGGRSVED--GPSA
RH-SL---------------PR--------------------------------------
-RNAPAS--CPEGDGSRTGVLSASSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAITAEDLSSPAGAVAFA----AKMPRCRGA------A
LAREESLEGDQAILQRIKKSVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLDKAWKDYEAK
TAFYQMER--VSTRFPEGGL-----SIHSMGTCKDHCVFSLCGCPYYLLKAGESQVKQGP
DFLQSLVKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLRQAQEEELQKLTQLRDSLR
GTLQLQNRE-----------EQETVGRKNSG---GGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
PRIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQTEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSS-GPGPCG-GAGLDGEPRDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAE------------------VKSRP-------GNG---QCCDCGA----PDPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTHFNEIMEAQLPSH
GGSKP-SAESDMSPRRDYIV-AKYVEHRFARRS-TLE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQRLWTAIYNRDLLSVLEAFANG
QDFGQTLPGPDGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAVRVANQASLPLVDFIIQNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

P

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNTAL
HYAALHNQPDCLKLLLKGRASVS--AVN

ENSGT00760000118874_5_Linker_5_6 (749, 750)

E

PF00023 // ENSGT00760000118874_5_Domain_6 (750, 770)

AGETALDVARKKQHKECQELLEQAQAGTLTF
PLHVDYSWGISVEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RYPLKLP--AQARWSSGRQDISNKTYEAIASLGSATPR----------------------
------------------------------------SQNEDFPPPLPVKNPSRTMVQGRV
GHAS----------------------------GDCSEAPSLSSEPPGTPES--LRS--PA
SSS--SSLTSPVEPGGPSQAL-PG------------------------SEESLQEPLGTT
RPSLLPGNTPAE---MYPPVRF---------------SSESTRSYRRGGRNLED--SPSA
RR-PL---------------PR--------------------------------------
-RNMPVG--FTEGDGSRTGVLPASSVQLLQD-----------------------------
--------------------------

----------------TFIEHLLCARHEDLSS----------------------------
RDFGNLFGNYQAILQR

PF16746 // ENSGT00760000118874_5_Domain_0 (77, 289)

IKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKVEKER--DRARVTGGIH-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFHDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLDSRE-----------GQEHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFHAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-AAGQDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDARAADGSTAV
HYAALYNQPDCIKLLLKGRALVG--TVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGISTEPGSESEEDEDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKPP--AQAHWASGRLDISNKTYETIASLGAATLQ----------------------
------------------------------------GESEDCPPPLPIKNSSRTMVQGCA
RRAS----------------------------GDRSEGPSLSSDASEAPES--LGS--PA
SSSSSSSLMSPTDPGGPSQAP-PS------------------------SEDGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSLED--GSSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FTEGDGSRTGTLPASSMQLLQD-----------------------------
--------------------------

------------MPERLSVAEFLAVTEEDLSSPAGAVAFA----AKMPRCRGA------A
LAWEEILEGDQAILQRIKKSVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIXXXXXXXXXXXXXXXXXXDSKKQLEKAWKDYEAK
VARLEKER--DRARVTGGSP-----GEVTQDTQRERRIFQLHMCE-YLLKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLRQAQEEELQKLTQLRDSLR
GTLQLESRE-------------ENVGRKNSG---GGYSIHQHQGNKQFGTEKVGFLYKKS
DGXXXX--XXXXXXXXXXXXXXXXXX--XIN

PF00169 // ENSGT00760000118874_5_Domain_2 (392, 445)

RPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQTEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSG-GPGSCG-GAGLDGEARDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAE------------------VKSRP-------GNG---QCCDCGA----PDPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDMLGPSELLL--ALNIGNMRFNEVMEAQLPSH
SGPKP-SAESDMSPRRDYIV-AKYVEHRFAHRY-PLE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQRLWRAVYNHDLLAVLEAFANG
QDFGQPLPGPDGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAVRVANQTSLPLVDFIIQNGGHLDTKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

P

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DENTAL
HYAALYNQANCLKLLLKGRASTS--AVNEAGETALDVARKKQHKECEELLEQAQAGILTF
PLHVDYPWGIFLEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AQARWGSGRMDISNKTYETITSMGSASPR----------------------
------------------------------------SHNENIPPPLPIKNPSRTMIQGRA
GHAS----------------------------GDCSEVSSLSSEPPEVPET--LGS--PT
SSS--SSLISPVDPGGLSQSP-PS------------------------CEKSLQEPLGPT
RPSLPSGTTPAE---IYLPVRF---------------SSESTRSYRRGGRSLED--SPSA
RR-PL---------------PR--------------------------------------
-RNMP-------------------------------------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGA-AAFAAKM-------

PF16746 // ENSGT00760000118874_5_Domain_0 (52, 288)

PR--YRGAA
LAREEILEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKLEKER--DRARVTGGIP-----GEVAQDMQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQED

ENSGT00760000118874_5_Linker_0_2 (288, 351)

ELQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSA-GPGSWG-SAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIM-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELV

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTFAF
PLHVDYSWVISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--AQAHWASGRLDISNKTYETVASLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTLVQGCA
RHAS----------------------------GDRSEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPLEPGDPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNVPVG--ITEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGA-AAFAAKM-------

PF16746 // ENSGT00760000118874_5_Domain_0 (52, 289)

PR--YRGAA
LVREEILEGDQAILQRIKKAVRAIHNSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKLEKER--DRAKVTGGIP-----GEVAQDMQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNVGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIM-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTDPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--AQAHWASGRLDISNKTYETVASLGAATPQ----------------------
------------------------------------GDSEDCPPPLPVKNSSRTLVQECA
RRAS----------------------------GDRCEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPLEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--ISEGDGSRTGSLPASSVQLLQE-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSAAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 289)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-DNEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAR
VARLEKER--ERARVTGGLP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GSLQLESRE-------------EHLRRKNSG---AGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLFTCQVRPNSEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGG-GPGSGT-GPGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNR---QCCDCGA----TDPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEIMEAQLPSH
GGTKP-SAESDMSTRRDYIV-AKYVEHKFAR

ENSGT00760000118874_5_Linker_3_5 (632, 703)

RS-ACEPQKLQAAIYNRDLLSVLEAFASG
QDFGQPLPGPDGQ----APGELALHLAIRVANQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 757)

IQNGGHLDAKAADGNTAL
HYAALHGQSDCLKLLLKGRASVG--TVNEAGETALDIVRKKQHKECEELLEQAQVGTLTF
PLHLDHSWGISVEPGSDSEDDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPLKPP--AQARWASGRLDISNKIYETIGSLGSASPQ----------------------
------------------------------------SQSEDCPPPLPVKASSRTMVQGRT
GHAS----------------------------GDRSEVSSLRSEPPEAPEG--LGS--PA
SSS--SSLTSPVESGVASQAL-PS------------------------SEEGLQEPPGTS
RAGLTSGITPSE---VYLPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMLVG--FTEGDRSKTGVLPANSL----------------------------------
--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------ESSEEAERERKVFQLHLCE-YLIKLGEAQIKQGP
DFLQCLIKFFQAQLNFFQDGLNAAQSLLPFIEKLSGTLHNIHHTRDEELKQLSEHRDNLQ
KQLQIDNKE-------------DGLSRKDSG---TGYSLHQPQGDKQYG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKSGFLYKKS
EGIRKV--WQKRKCGVKYGNLTISHS--TINRPPAKIKLLTCHVRPNVEDKRNFDLITHN
RTYHFQAEDENEALVWISVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DESMNAAFGGDGGFI------------DSPHQIN

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 637)

KQ
IINE------------------IRSLP-------GNQ---VCCDCGA----PEPSWVSTN
LGILICIECSGIHRDLGVRYSRVQSLTLDLLSTSELLL--AVSVGNTKLNEVLEATLPAF
NTKP--NPTSDMITRKDYIS-AKYVEHSFVSKDRTD

ENSGT00760000118874_5_Linker_3_4 (637, 679)

SFHRVRAAIQSCDLTALLQCMASG
ADLSKPIPSMDSQ----D

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

LSESPLHFAIRMSDRSSLPVVDFIIQNGGALDKVT

ENSGT00760000118874_5_Linker_4_5 (714, 715)

T

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGHTAL
HYGVKYNKLDCIRLLLRAKASLT--AGN

ENSGT00760000118874_5_Linker_5_6 (749, 750)

N

PF00023 // ENSGT00760000118874_5_Domain_6 (750, 786)

DGLTPLMLAQSMKHTDCEELLEKAATGCFVC
--DVDFDWFHQDEEESNSEDDEGEKIGKKLLPHTSPAQ----------------------
------------------------------------------------------------
--------------------------------------------------------SPKS
HTLIHAPIKLPPRHSSMGLDISNKTYETINIPQRGPPPHRSRSLETPPP-----------
---------------------------------------------LPAKTHPRS------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSPAGAN-AFAAKMSRC---------RGAA
LAREEILEGDQAILQ

PF16746 // ENSGT00760000118874_5_Domain_0 (76, 289)

RIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNMNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKVEKER--DRARVTGGIH-----GEVAQDMQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLNSRE-----------GQEHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFHAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-AAGQDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSG------VRFSRMQSLTLDLLGPSELLL--ALNIGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGHLDARAADGSTAV
HYAALYNQPDCIKLLLKGRALVG--TVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGISTEPGSESEEDEDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKPP--AQAHWASGRLDISNKTYETIASLGAATLQ----------------------
------------------------------------GESEDCPPPLPIKNSSRTMVQGCA
RRAS----------------------------GDRSEVHSLSSDAPEAPVS--LGS--PA
SSSSSSSLMSPTDPGHSSQAP-SS------------------------SEDGLQEPPGTS
RPSLTSGTTPSE---MHLPVRF---------------SSESTRSYRRGARSLED--GSSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FTEGDSSRTGTLPASSMQLLQD-----------------------------
--------------------------

------------------------------------------------------------
------LEGDQAILQRIKKSVRTIHSSGLAHV-ENEEQYSEALETFGNSHLSQNNHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSRKQVEKAWRDYETK
MARLEKEK--ERSRMAGGGP-----GEAAQDTQRERRVFQLHMCE-YLLKASENQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHSVSYIAW---------RDG--
-QLSLWSEE-----------D---IRVKGSSRW-QNGSQEEEGKRWRFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKSGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPSTEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFQGESGGGLQGSPV-GPGLDGDLRDLTRL
I

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------IKSRP-------GNS---QCCDCGA----SDPTWLSTN
LGILTCIQCSGVHRELGVRFSRIQSLTLDVLGPTELLL--AVGIGNTHFNEIMEAQLTLN
GAVKP-SSESDMSTRRNYIV-AKYVEHRFARRG-GYEPHRLWTAICNRDLPAVLEAFANG
LDFGQPLPRPDGQ----PSGELALHLAVRLADQTSLPLVDFIIQNGGHVDAKAL

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNTAL
HLGALHNQADCIKLLLKGRASVG--TVNDAGETALEVARKTRHKECEDLLEQAQAGTLIL
PLHIDYPWGVSPDPASESEEEEED------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPIKLPAPARPRWGCSGLDISNKTYETIVSLGPTQTNNRK-------------------
------------------------------------AHTEELPPPLPVKSPSRASSQGRI
GHGS----------------------------GDGPEVLSSGSEPPGSLES--PSVFSPS
TSSIPSPTE---SPRGPGQTE-AC------------------------SEENLWEASGTA
HPLPSSGTTSPE---QLPPVRF---------------SSESTRSYRRGGRGLED--TPVA
RQLPPG--------------PL--------------------------------------
-ARRAVSDGVTEADGSKTGLLLASSVKLSQD-----------------------------
--------------------------

MDGALFC--ALRLPHHVTLGKGL-------LSL-GFSFLIYGPFPALTFC---------A
FQVNCILEGDQAILQRIKKA

PF16746 // ENSGT00760000118874_5_Domain_0 (81, 289)

VRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVIGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGS----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTVEDLNSPAGAAAFA----AKMPRCRGA------A
LVREEMLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEHYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKHLEKAWKDYEAK
MARLEKER--DRARVTGGSH-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEELQKLTQLRDSLR
GTLQLENRE-------------ENMSRKNSG---GGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKN
PRIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFQGEPSG-ILGPWG-AAGLDGELQDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLCPSELLLQLALNIGNTRFNEVMEAQLPSH
GGPKP-SADSDMSARRDYIV-AKYVEHRFARRS-TPE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQRLWMAICNQDLLSVLEAFANG
QDFGQLLPGPEGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAVRVANQASLPLVDFIIQNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGNSAL
HYAALYNQPDCLKLLLKGRASVG--PVN

ENSGT00760000118874_5_Linker_5_6 (749, 750)

E

PF00023 // ENSGT00760000118874_5_Domain_6 (750, 770)

EGETALDIARKKQHKECEELLEQAKAGTLAF
PLHVHYSWGVSTEPGSDSEEDEEEK-----------------------------------
------------------------------------------------------------
-----------------------------------------------------------Q
HCPLKPP--AQVHWASGRMDISNKTYETITNLGSAAPQ----------------------
------------------------------------SQSEDCPPPLPVKNPSRTTVQGRA
GHTS----------------------------GDHPEVPSLSSESPGAPES--QNS--PT
SSS--SSLTSPVELGGTNQTP-PS------------------------SEEGLCEPPGTS
RPSLTSGRLSREGGDIGLSLLS---------------SSESTRSYRRGQNLE---DCPSA
TQ-PP---------------PR--------------------------------------
-RNMLVG--FTEGEGSRTGVLPASSVLLLQD-----------------------------
--------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MKGHLRDGRQDSRKHLEKAWKDYEAK
VTRLEKER--DRTRMTGGSP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLHQAQEEELQKLTQLRDSLR
GSLQLDSRE-------------EHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEDKKCFDLVTHS
RTYHFHAEDEQECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSS-GPGPWA-GAGLDAEPQELTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNG---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNMRFNEVMEAQLPSH
RSPKP-TAESDMSTRRDYIV-AKYVEHKFARRC-TPEPQRLRTAICNRDLLSVLEAFANR
QDFGQPLPGPDGQ----APGELALHLAVQVASPASLPLVEFIIQNGGHLDAKAA

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 737)

DGNTAL
HYAALANQPDCLKLLLKGRAVAG--TVNEAGETALDIARRKQHKECEELLEQAQAGTLTF
PLHVDYSWGISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCSLKPS--AQAHCAGGRLDITNKMYETLGSLGAAPPQ----------------------
------------------------------------SQSEACPPPLPVKHSARSTLQGRA
GPGV----------------------------ADHSEVPSLSVEHPESPES--PGS--PA
SSC-SSSLTSPVDPGGPSQAP--L------------------------SSENLREALGAS
RFSLIPGTTPTE---THLPVRFRHHGD---FGLSLPSSSESTRSYRRGGRSLED--SPSA
RQ-PV---------------PR--------------------------------------
-RNAPAG--CTEGDGSRPGVLPASSVQLLQD-----------------------------
--------------------------

------------MPEQFSVAEFLAVTAEDLSSP-AGAATFAAKMPRCRGA---------A
LAREEILEGDQ

PF16746 // ENSGT00760000118874_5_Domain_0 (72, 291)

AILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVIGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEELQ

ENSGT00760000118874_5_Linker_0_2 (291, 351)

KLTQLRDSLR
GTLQLESRE-----------GQEHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNMSFNEVMEAQLPSH
GGPKP-SPESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVDYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RRAS----------------------------GDHSEVSSLSSEAPETPEN--LGS--PA
SS---SSLMSPVEPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---MYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

--------------------------------------ME----SGTPPSWA---SLNSI
HICFQILEGDQAILQRIK

PF16746 // ENSGT00760000118874_5_Domain_0 (79, 290)

KAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDHEAK
MARLEKER--DRARVTGGSP-----GEVAQDTQRERRVFQLHMCE-YLLRAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GTLQLESRE-------------ENLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNAEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGPWG-GAGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-SAESDMSSRRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-APEPQRLRTAICNRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVATQASLPLVDFIIQNGGHLDTKAADGNSPV
HCAALYNQPDCLKLLLKGRASVG--TVNEAGETALDIARKKQHKECEELLEKAQAGTLAF
PLHVDYSWGLSTEPGSDSDEEEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AQTRWASGRVDLSNKTYEAIATLGAAAPQ----------------------
------------------------------------SESEACPPPLPVKNPSRTMVQGRV
GHTS----------------------------ADRSEVPSLSLEPSGAPES--LGS--PA
STP--SSLTSPGEAGGPSQTPPPS------------------------SEEGLWEPPGPS
RPSLTSGATPTE---MYPPVKF---------------SSESTRSYRRGGPEPGRLSLSQT
AS-V--------------------------------------------------------
-QKEH------------AGWLH--------------------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSAAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 289)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-DNEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAR
VARLEKER--ERARVTGGLP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GSLQLESRE-------------EHLRRKNSG---AGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLFTCQVRPNSEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGG-GPGSGT-GPGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNR---QCCDCGA----TDPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEIMEAQLPSH
GGSKP-SAESDMSTRRDYIV-AKYVEHKFAR

ENSGT00760000118874_5_Linker_3_5 (632, 703)

RS-ACEPQKLQAAIYNRDLLSVLEAFASG
QDFGQPLPGPDGQ----APGELALHLAIRVANQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 757)

IQNGGHLDAKAADGNTAL
HYAALHGQSDCLKLLLKGRASVG--TVNEAGETALDIVRKKQHKECEELLEQAQVGTLTF
PLHLDHSWGISVEPGSDSEDDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPLKPP--AQARWASGRLDISNKIYETIGSLGSASPQ----------------------
------------------------------------SQSEDCPPPLPVKASSRTMVQGRT
GHAS----------------------------GDRSEVSSLRSEPPEAPEG--LGS--PA
SSS--SSLTSPVESGVASQAL-PS------------------------SEEGLQEPPGTS
RAGLTSGITPSE---VYLPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMLVG--FTEGDRSKTGVLPANSL----------------------------------
--------------------------

--SGLTA----------------ALTSPGSGDPPTSASQVAGTIGRCHHMEMG--FWQVV
QAGLEILEGDQAILQRIK

PF16746 // ENSGT00760000118874_5_Domain_0 (79, 289)

KAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYETK
MAKLEKER--DRARVTGGIP-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLESRE-------------EHLSRKNSG---CGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GLGSWG-AAGHDGEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNMGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 703)

RRC-TPEPRRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDAQ----APEELALHLAIKVASQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 758)

IQNGGHLDAKAADGNTAL
HYAALYNQPDCLKLLLKGRALVG--TVNEAGETALDIARKKHHKECEELLEQAQAGTLAF
PLHVAYSWVISTEPGFDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCLLKLP--VQAHWASGRLDISNKTYETVTSLGAATPQ----------------------
------------------------------------GESEDCPPPLPVKNSSRTVVQGCA
RHAS----------------------------GDHSEVSSLSSEAPETPES--LGS--PA
SS---SSLMSPVGPGGPSQAP-PN------------------------SEEGLREPPGTS
RPSLTSGTTPLE---VYLPVRF---------------SSESTRSYRRGARSPED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--VTEGDGSRTGSLPASSVQLLQD-----------------------------
--------------------------

-----------------------------------MWMVDSGFLEKVPPTQPS--IPEPL
SICFQSLEGDQVILQKIKKSVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREMAALFKNLVQNLNNIVSFPLDSLLKAQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVTGGSP-----GEVAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHTLRQAQEEELQKLAQLRDSLR
GTLQIESRE-------------ENLSRKNSG---GSYNIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNLEEKKCFDLVTHN
RTYHFQTEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 532)

SKDEALSSAFLGEPGG-GPGPWA-GAALDGEQPGPRQA
AHRRGEEPARERPMLRLRSCRSVGPGPEGGWERRGGGRTPRHELLYL----

PF01412 // ENSGT00760000118874_5_Domain_3 (532, 632)

ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMHSLTLDLLGPAELLL--ALNIGNARFNEVMEAQLPSH
GGPKP-SVESDMSTRREYIV-AKYVERRFARRS-TPEPQRLWTDICNRDLLSVLEAFANG
QDFGQPLPAPDGQ----APGELALHLAVRVANQASLPLVDFIIQNG--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 290)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGPLRDGRQDSKKQLEKAWKDYEAR
MARLEKER--DRARVTGGSP-----GEVTQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLAQLRDSLR
GTLQLENRE-------------EHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFHLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSS-GPASWV-GAGLDGESQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTGFNEVMEAQLPSH
GGPKP-SAESDMNARRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-TPEPQRLWTAICNRDLLAVLEAFANG
QDFGQPLPGPDGQ----VPGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 770)

LHLAIKVASQASLPLVDFIIQNGGHLDAKAEDGNTAL
HCAALHGQADCIKLLLRGRAAVG--TVNEAGETALDVARKKQHKECEELLDQAQAGTLTF
PLHVDYPWAMSMEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AQARWASGRLDISNKTYETFTSLGPAAQQ----------------------
------------------------------------SQSEDCPPPLPIKSSSRTTVQGRA
GHAN----------------------------GD-PEVPSLSSEPPEASES--LGS--LA
TSS--SSLTSPMEPGGASQGL-LS------------------------SEEGLQETPGTS
RPSLAPGATPAE---VYLPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PV---------------PR--------------------------------------
-RSTQVG--FPEGDGAKTGVLPASSVRLLQD-----------------------------
--------------------------

-----------------------------------------------------------L
SLLLQSLDGDQAVLQRIRKYVKAIHISGLTHV-ENEEQYSEALENFGNNHLSQNNHELST
GFLNLAVFTREVTALFKNLVQNLNNIVSFPLDSLLKGQLKDGRLDSKKQIEKAWKDYETK
VGKMEKEK--ERARLAGVIQAEPAAAEMAEDMQKERRLLQLHMCE-YLLKARESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQNLYPFIEKLAVSLHALRQAQEEEVKQLTQTRDSLR
SILQLESKE-------------ENLNRKNSG---SGYSIHQHQGNKQYGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKSGFLYKKS
DGIRKV--WQKRKCGVKYGCLTISHS--TINRPPVKLNLLTCQVRPHAEEKKCFDLVTHN
RTYHFQAEDEQDCVVWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSNAFKGDGR---------STGADSGMQELTRL

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

VISE------------------VKNMP-------GNK---QCCDCSA----PDPTWLSTN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLL--AVSIGNTRFNEIMEAALPTQ
DCPKP-AASSDMAARKEYIM-AKYMERRYVQKSSQDNPHSLWEAIQARDLLALLKAFADG
HDLTKPLASPEGQ----DAGELPLHMAVRHADRSSLPLVDFIIQNGGTLDRVTQ

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 740)

NGNTAL
HYGALYNQPNCLKLLLKGKATFT--TVNAAGETALDVARRLKYSECEELLEQAQAGKLSL
QIHVDYDWEPASEFPYDSDDELEEK-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------------------------------------------------------
----QTLDGDQAILQRIRKYVKAIHVSGLTHV-ENEEQYSEILENFGNNHLSQNNHELST
GFLNLAVFTREVTALFKNLVQNLNNIVSFPLDSLLKGQLKDARSESKKQIEKAWKDYETK
VAKLEKEK--ERSKISSVIQTELSAAEIAEDLQKERRTFQLQMCE-YLLKANESQMKQGP
DFLQSLIKFYHAQHNFFQDGWKASQNLYPFIEKLATSLHALRQAKEEEVKQLTHIRDSLR
GLLQMENKG-------------ENLNRKNSG---SGYSIHQHQGNKQYGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKSGFLYKKS
DGIRKV--WQKRKCGVKYGFLTISHS--TINRPPVKLNLLTCQVRPHSEDKKSFDLVTHS
RTYHFQAEDEQECVVWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDESLSKAFKGDPGSCVSS-A--AGVADTGLQELTKL

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

IIAE------------------VKNLP-------GNR---HCCDCGA----PDPTWLSTN
LGILTCIECSGIHRELGVHYSRIQSLTLDVLSTSELLV--SDSIGNPKFNDVMEALCGTR
QLKPPRPATCCRVARKEFIM-AKYMERKYVHKSAKDEPHRVWEAVRSRDLLATLQAFAEG
HDLAKPLASPDGQ----EPGERALHLAVRWANRSSLPLVDFIIQNGGNLDSPAP

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 748)

DGNTAL
HYGAQCNQPNCIKLLLKGKASTS--AVNAAGETPLDVAKKYKHTECEDLLEQAQMGRMVA
PIHVDYDWEAPQEFSYDSEDELDEKQPS--------------------------ALLL--
------------------------------------------------------------
------------------------------------------------------------
--------PLADRWSCSGMDITNKTYESLLVPSRPGSEETPPPLPLKKPTR---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPTGAAAFA----AKMPRCRGA------A
LAREEVLEGDQAI

PF16746 // ENSGT00760000118874_5_Domain_0 (74, 291)

LQRIKKAVRAIHSSGLGHV-ENEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRHDSKKHLEKAWKDYEAK
VAKLEKER--DRARVTGGSH-----GELSQDTQRERRVFQLHMCE-YLVKARESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHVLRQAQEEELH

ENSGT00760000118874_5_Linker_0_2 (291, 351)

KLTQLRDSLR
GMLHLESRE-------------EHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--MINRPPVKLTLLTCQVRPNPEEKTCFDLVTHN
RTYHFHAEDELECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFNGEPGGGQ-GSWG-SARLDSEPQDLTKM
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

VAE------------------VKSRP-------GND---HCCDCGA----SDPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLGPSELLL--ALNIGNSHFNEIMEARLPSH
GSPKP-SAESDMSSRRNYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

QS-TPDPQRLRTAICSRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASQASLPLVDFLIQNGGHLDAKAADGNTAL
HCAALHGQLDCLKLLLKGRAPVG--AVNDAGETALDIARKKQHKGCEELLEQAQAGTLAF
HLHVDYPWGHSMGHGFDSEEEEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
HCPVKPP--AQACWGSGRLDISNKTYETLASPEPATSQ----------------------
------------------------------------SQSEDSPPPLPMKSSSRTMHPGRA
GHSN----------------------------GDRSDTPSLRSESPEASEN--PSS--PA
SSL--SSLTSSMEPGGLSQAP-PS------------------------PEEGLQETPGTS
RPGPASGTTPPE---LYLPVKF---------------SSESTRSYRRGGRILED--SPSA
RH-PL---------------SR--------------------------------------
-RNIPVV--LGEGDGSKTGALAASSLQLLHD-----------------------------
--------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MKGQLRDGRQDSKKQLEKAWKDYEAK
VARLEKER--DRARVPGGSP-----GEMAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEELQKLTQLRDSLR
GTLQLEGRE-------------EHLGRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-STGQDSEPHDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTSFNEVMEAQLPSH
GGPKP-SAESDMSTRRDYIV-AKYVEHRFARRS-TPEPQRLRTAICNRDLLSILEAFANG
QDFGQPLPGSDTQ----VPGELALHLAVKVTNQASLPLVDFIIQNGGHLDAKAT

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 742)

DGNTAL
HYAALCNQPDCLKLLLKGRASVGTDTVNEAGETALDIARKKQHKECEELLEQAQAGTLTF
PLHLDYPWGISTEPGSDSEEDEEEKVGPPASQASRWPKE---------------------
------------------------------------------------------------
------------------------------------------------------RARVGL
RCPLKPP--AHARWVSGRLDISNKTYETITSLGSATPQ----------------------
------------------------------------SQSEDCPPPLPVKNTSRTTVQGCV
RHAS----------------------------GDRSEVPSLSSETSEAPES--LGS--PA
SSS--SSLASPVEPGGPSQLP-PS------------------------SEESLREPPGTC
RHSLTSGTTASE---MYLPVKF---------------SSESTRSYRRGGRSLED--GSSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FPEGDSSRTGVLPTSSVQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAVTAEDLNSPAGAAAFA----AKMPRCRGA------A
LAREEILEGDQA

PF16746 // ENSGT00760000118874_5_Domain_0 (73, 290)

ILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVTGGSP-----GETAQDTQRERRVFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GTLQLEGRE-------------EHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDERECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-SPGSCG-GTGQDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTSFNEVMEAQLPSH
GGPKP-SAESDMSARRDYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

RS-TPEPQRLWTAICNRDLLSVLEAFANG
QDFGQPLPGPDTQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNAGHLDAKAADGSTAL
HCAALHSQPDCLKLLLKARAPVG--AVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGIATEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AHARWVGGRLDISNKTYETVASLGPATLQ----------------------
------------------------------------SQSEDCPPPLPVKNSSRTMVQGCA
RLAS----------------------------GDHSEVPSLSSEPSEAPES--LGS--PA
SSS--SSLTSPMEPGSPSQAP-PS------------------------SEEGLREPPGTS
RPSPTAGTTASE---TYPPVRF---------------SSESTRSYRRGGRSLED--GPSA
RQ-PL---------------PK--------------------------------------
-RNMPVG--APGLWFEGQWWQGAWEAELLRSRCVGVGDLSPRLE----------------
--------------------------

------------MPEQLSVAEFLAVTAEDLSSPAGANAFA----AKIPRCRGA------A
LAREEMLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAR
MARLEKER--DRARVTGGTP-----GEVAQDTQRERRVFQLHMCE-YLLRAGESQLKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEELQKLIRLRDSLR
GTLQLDSRE-------------ETLSRKNSGGGGGGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLAEPSGGGPGPWG-GAGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPAQ
GGPKP-SAESDMSTRRDYIV-AKYVEHRFARRS-TPEPQRLRTAICNRDLLSVLEAFANG
QDFGQLLPGPEGQ----APGELALHLAIRVASPASLPLVDFIIQNGGHPDAKAA

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 746)

DGNSAL
HWAALYNQPDCLKLLLKGRASLG--TVNEAGETALDIARKKQHKECEELLEQAQAGTLTF
PLHVDYNWGISPEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RSPLKPP--AQARWASGRVDLSNKTYETIANLGSAAPQ----------------------
------------------------------------SQSEACPPPLPVKNPSRTMVQGRA
GHAS----------------------------GDRSEVPSLSCEPSGAPES--LGR--PA
STS--STLTNPVDAAGPSQTP-PS------------------------SEEG------PS
RPSLTSGGTPAE---MYPPVRF---------------SSESTRSYRRGGLEPGRLSLSQ-
---AA---------------SA--------------------------------------
-HKEHAG--MSSGTVVRGVVAGHVGGRVGQQSMGGVGSWGPLPMARVYRRLGGHSSASPL
RWCAPFPLQPGTHEAGESPGLEGRQR

------------MPEQLSIAEFLAVTAEDLSSPAGAATFA----SKMPRCRGA------A
LAREEVLEGDQAI

PF16746 // ENSGT00760000118874_5_Domain_0 (74, 290)

LQRIKKAVRAIHSSGLGHV-ENEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLESLMKGQLRDGRHDSKKHLEKAWKDYETK
MAKLEKER--DRARVTGGGH-----GEMLQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GMLHLESRE-------------EHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKHGCLTISHS--MVNRPPVKLTLLTCQVRPNPEEKTCFDLVTHN
RTYHFHAEDELECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSSAFNGEPSGGQWSWGG-TPRLDAEPQDLTKM

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

LIAE------------------VKSRP-------GNG---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLSPSELLL--ALNMGNSRFNEVMEAHLPAL
GSPKP-CAESDMSSRRNYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

QS-TPEPQKLWTAIRNRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASRASLPLVEFLIQNGGHLDAKTVDGNTAL
HCAALHGQLDCLKLLLKGRAPVG--AVNDAGETALDIARKKQHKGCEELLEQAQAGTLTF
PLHMDYPWGHSMEHGCDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
YCPGKPP--ARDCWGNGRLDI-NKTYETIIVPGPATSQ----------------------
------------------------------------SHKEDRPPPLPAKNS-RTTLPGRA
GHSS----------------------------GDRSDTPSLRSESPEASEN--PSS--PA
SSS--SSLTSSVEPGGLSLAP-PS------------------------PKEGLQEPSGTS
RPRPESGTTPIE---VYLPVKF---------------SSESTRSYRRGGRSLED--SPSA
WQ-PL---------------SR--------------------------------------
-RNIPVC--LTEGDGSKTGVLPASSLQ-LLHD----------------------------
--------------------------

------------MPEQFSIAEFLAATAEDISSPAGAA-AFATKMSRC---------RGAA
LAREEILEGDQAILQ

PF16746 // ENSGT00760000118874_5_Domain_0 (76, 289)

RIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAK
MAKVEKER--DRARVTGGIH-----GEVAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEE

ENSGT00760000118874_5_Linker_0_2 (289, 351)

LQKLTQLRDSLR
GTLQLDSRE-------------EHLSRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFHAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPSG-GPGSWG-TAGQDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 631)

IAE------------------VKSRP-------GNS---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNVGNTSFNEVMEAQLPSH
GGPKP-SAESDMGTRRDYIV-AKYVEHRFA

ENSGT00760000118874_5_Linker_3_5 (631, 684)

RRC-TPEPQRLWTAICNRDLLLVLEAFANG
QDFGQPLPGPDAQ----APEELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 771)

LHLAVKVANQASLPLVDFIIQNGGPLDARAADGSTAV
HYAALYNQPDCIKLLLKGRALVG--TVNGAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYSWGISTEPGSESEEDDDE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RYLLKPP--AQAHWASGRLDISNKTYETIASLGAANLQ----------------------
------------------------------------GESEECPPPLPIKNSSRTMVQGCA
RRAS----------------------------GDRSEVPSLSSDASEAPES--LGS--PA
SSSSSSSLMSPTDPGGPSQAP-PS------------------------SEDDLREPPGTS
RPSLTSGTTPSE---MYLPVRF---------------SSESTRSYRRGARSLED--GSSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FTEGDGSRTGTLPASSMQLLQD-----------------------------
--------------------------

------------MPEQLSVAEFLAITAEDLSSAAGAAAFA----AKMPRCRGA------A
LAR

PF16746 // ENSGT00760000118874_5_Domain_0 (64, 290)

EEVLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVESLGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAR
VARLEKER--ERARVTGGFP-----GEAAQDTQRERRIFQLHMCE-YLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GSLQLENRE-----------GQEHLRRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 482)

SKDEALSSAFLGEPGG-GPGSGT-GPGLDGEPQDLTKL
L

PF01412 // ENSGT00760000118874_5_Domain_3 (482, 632)

IAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSEMLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-SAESDMSTRRDYIV-AKYVEHKFAR

ENSGT00760000118874_5_Linker_3_5 (632, 703)

RS-SWEPQKLQAAISNRDLLSVLEAFASG
QDFGQPLPGPDGQ----APGELALHLAIRVANQASLPLVDFI

PF13857 // ENSGT00760000118874_5_Domain_5 (703, 757)

IQNGGHLDAKAANGNTAL
HYAALHGQLDCLKLLLKGRASVG--TVNEAGETALDIVRKKQHKECEELLEQAQAGTLTF
PLHLDYSWGISMEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
PCPLKPP--AQARWTSGRLDISNKTYETIGSLGPATLQ----------------------
------------------------------------SQSEDCPPPLPVKASSRTVVQGRA
GHVS----------------------------GDRSEASSLSSEPPEASES--LGS--PA
SSS--SSLTSPVEPGGPSQAL-PS------------------------SEEGLREPPSTS
RAGLTSGTIPAD---MYPPVRF---------------SSESTRSYRRGARSLED--GPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FPEGDGSKTGILPASSL----------------------------------
--------------------------

------------------------------------------------------------
----QTLEGDQAILQRIKKAVRAIHSSGLGHV-ENEEQYREAVX-LPPSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAK
MARLEKER--DRARVPGGSP-----GEVAQDTQRERRVFQLHMCE-YLLRAGESHMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALRQAQEGELQKLTRLRDSLR
GALQLESRE-------------ESLSRKNSG-GGGGYSIHQHQGNKHFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
SRIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 475)

DEALSSAFLAEPSGGGPGPCG-GAGLDGEP

PF01412 // ENSGT00760000118874_5_Domain_3 (475, 638)

QDLTKL
LIAE------------------VK----------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-SAESDMSTRRDYIV-AKYVEHRFARRS-TPE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PQRLRTAICNRDLLSVLEAFANG
QDFGQLLPGPEGQ----A

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

PGELALHLAIRVASPTSLPLVDFIIQNGGHLDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

A

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DRNSAL
HWAALYNQADCLKLLLKGRASIG--TVNEAGETALDIARKKQHKECEELLEQAQAGTLAF
PLHVDYNWGLSTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RSPLKPP--AQARWASGRVDLSNKTYETIASLGSAAPQ----------------------
------------------------------------SQSEACPPPLPVKNTSRTMVQGRA
GHAS----------------------------GDRSEVPSLSSELSAAPES--LGS--PA
ST--PSSLTSPVDAAGPTQTP-PS------------------------SEEG------PS
RPSLPSGTTPAE---TYPPVRF---------------SSESTRSYRRGGSLE---DCPSA
RQ-PL---------------PT--------------------------------------
-RNMPLV--GEPGSGHRTGPVGGSPGSSVQPLQG--------------------------
--------------------------

------------------------------------------------------------
-----TLEGDQAILQRIKKSVRTIHSSGLAHV-ENEEQYSEALETFGNSHLSQNNHELST
GFLNLAVFTREVAALFKNLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XVRLEKEK--ERSRMPGGGP-----GEAAQDPQRERRVFQLHMCEXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXFFQDGWKAAQSLSPFIEKLAASVHSLHQAHEEDIQKLTQIRDSLR
GALQLESRE-------------ETSSRKNSG---SGYSIHQHQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKSGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPSMEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFHGEAGGGSRE----PAGLDGDLRDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

RL
VIAE------------------IKSRP-------GNG---QCCDCGA----SDPTWLSTN
LGILTCIQCSGVHRELGVRFSRIQSLTLDVLGPAELLL--AVGIGNTQFNEIMEAQLSAN
GASKP-SSESDMSTRRNYIV-AKYVEHRFARRA-GYE

ENSGT00760000118874_5_Linker_3_4 (638, 679)

PHKLWTAICNRDLPAVLEAFANG
LDFGQPLPRPDGQ----T

PF00023 // ENSGT00760000118874_5_Domain_4 (679, 714)

SGELALHLAIRLADQTSLPLVDFIIQNGGHVDAKA

ENSGT00760000118874_5_Linker_4_5 (714, 715)

P

PF00023 // ENSGT00760000118874_5_Domain_5 (715, 749)

DGSTAL
HLGALHNQPDCLKLLLKGRASVG--TVNDAGDTALEVARKNQHKECEDLLEQAQAGTLIL
PFHINYPWGVSVDPGSESEDEEED------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPIKLPAPARPRWGCTGLDISNKTYETIVSLGPTQASNRR-------------------
------------------------------------SHTEELPPPLPVKSPSRASSQGRI
GHGS----------------------------GXXXXXXXXXXXXXXXXXX--XXXXXXX
XXX--XXXXXXXXXXXXXXXX--X------------------------XXXXXXX---XX
XXXXXXXXXXXX---XXXXXXX---------------XX-XXXXXX--XXXXXX--XXXX
XXXXXX--------------XX--------------------------------------
-XXXXXXDGITEVDSSKAELHLASSGKLSQD-----------------------------
--------------------------

------------------------------------------------------------
-----MLEGDQAILQRIKKAVRAIHSFGLXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXVQNLNNIVSFPLDSLLKGQLRDGRQDSKKQLEKAWKDYEAK
XXXXXXXX--XXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXYLLKAGESQMKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIEKLAASVHALHQAQEEELQKLTQLRDSLR
GTLQLESRE-------------ETLSRKNSG---GGYSIHQQQGNKQFG

PF00169 // ENSGT00760000118874_5_Domain_2 (350, 445)

TEKVGFLYKKS
DGIRRV--WQKRKCGVKYGCLTISHS--TINRPPVKLTLLTCQVRPNPEEKKCFDLVTHN
RTYHFQAEDEHECEAWVSVLQNSK

ENSGT00760000118874_5_Linker_2_3 (445, 479)

DEALSSAFLGEPSG-GPGPWG-GAGLDGEPQDLT

PF01412 // ENSGT00760000118874_5_Domain_3 (479, 638)

KL
LIAE------------------VKSRP-------GNG---QCCDCGA----ADPTWLSTN
LGVLTCIRCSGVHRELGVRFSRMQSLTLDLLGPSELLL--ALNIGNTRFNEVMEAQLPSH
GGPKP-STESDMSTRRDYIV-AKYVEHRFARRS-TPEPQRLWMAICNRDLLSVLEAFANG
QDFGQPLPGPEGQ----APGELALHLAVRVTNQASLPLVDFIIQN---------------
---------------------------NEAGETALDIARKKQHKECEDLLEQAHAGTLAF
PLHLDYPWGISTEPGSDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
RCPLKPP--AQVRWASGRLDISNKTYETIASLGPAAPK----------------------
------------------------------------IQSEDCPPPLPVKNPSRTMAQGRA
GHAS----------------------------GDRSEVPSLSSESAGVPES--LSS--PA
SSS--CSLTSPVEPGGPNQTL-PS------------------------SEEGLWEPPGPS
RPSLTSGTTPSE---MYPPVRF---------------SSESTRSYRRGGRSLED--CPSA
RQ-PL---------------PR--------------------------------------
-RNMPVG--FTEGDGSRTGVLPASSVQLLQD-----------------------------
--------------------------

------------MPEQLSIAEFLAVTAEDLSSPAGAATFA----SKMPRCRGA------A
LAREEVLEGDQAI

PF16746 // ENSGT00760000118874_5_Domain_0 (74, 290)

LQRIKKAVRAIHSSGLGHV-ENEEHYREAVEALGNSHLSQNSHELST
GFLNLAVFTREVAALFKNLVQNLNNIVSFPLESLMKGQLRDGRHDSKKHLEKAWKDYETK
MAKLEKER--DRARVTGGGH-----GEMLQDTQRERRVFQLHMCE-YLVKAGESQVKQGP
DFLQSLIKFFHAQHNFFQDGWKAAQSLSPFIDKLAASVHGLRQAQEEEL

ENSGT00760000118874_5_Linker_0_2 (290, 351)

QKLTQLRDSLR
GMLHLESRE-------------EHPNRKNSG---GGYSIHQHQGNKQFGT

PF00169 // ENSGT00760000118874_5_Domain_2 (351, 443)

EKVGFLYKKS
DGIRRV--WQKRKCGVKHGCLTISHS--MVNRPPVKLTLLTCQVRPNPEEKTCFDLVTHN
RTYHFHAEDELECEAWVSVLQN

ENSGT00760000118874_5_Linker_2_3 (443, 481)

SKDEALSSAFNGEPSGGQWSWGG-TPRLDAEPQDLTKM

PF01412 // ENSGT00760000118874_5_Domain_3 (481, 632)

LIAE------------------VKSRP-------GNG---HCCDCGA----ADPTWLSTN
LGVLTCIQCSGVHRELGVRFSRIQSLTLDLLSPSELLL--ALNMGNSRFNEVMEAHLPAL
GSPKP-CAESDMSSRRNYIV-AKYVEHRFAR

ENSGT00760000118874_5_Linker_3_5 (632, 684)

QS-TPEPQKLWTAIRNRDLLSVLEAFANG
QDFGQLLPGPDGQ----APGELA

PF12796 // ENSGT00760000118874_5_Domain_5 (684, 772)

LHLAIRVASRASLPLVEFLIQNGGHLDAKTVDGNTAL
HCAALHGQLDCLKLLLKGRAPVG--AVNDAGETALDIARKKQHKGCEELLEQAQAGTLTF
PLHMDYPWGHSMEHGCDSEEDEEE------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
YCPGKPP--ARDCWGNGRLDI-NKTYETIIVPGPATSQ----------------------
------------------------------------SHKEDRPPPLPAKNS-RTTLPGRA
GHSS----------------------------GDRSDTPSLRSESPEASEN--PSS--PA
SSS--SSLTSSVEPGGLSLAP-PS------------------------PKEGLQEPSGTS
RPRPESGTTPIE---VYLPVKF---------------SSESTRSYRRGGRSLED--SPSA
WQ-PL---------------SR--------------------------------------
-RNIPVC--LTEGDGSKTGVLPKPSGLGEVRDQERKEELGR-------------------
--------------------------