Query Results 

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAAS--------------------
-----P-PKPGKDPAPPS-PTSTSPAVQPG--EEAQGDDLSPDSLSEQ--GKQQPPSSA

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
SRSGTRPLSQQRQQPAA---------AE-----A---KD-----------------TEDN
DPSLS--V-----------A--AVAETDR---LQASSE----VQFH---TPTKPPLPSKP
--------QELAS-PPVGRPTPAPRKASESSALTPP----TPRPRSSLQQDGTVEQSV--
SSGLVNG---------RLQ--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERMA--ASRKDPPWITLVQTEP-KKKPAPQPP-SSGPGP--LSQAY
RQVEDGGLEERTQKSP----GTEPEPKPYNPFEEEEEEEGEPAPAVPSP-----------
----------------SPAPPV------------------PSPSPAPPVPSPAP-TPSEA
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LATHA---SRLSHSEPPSATP-------SPALS--MESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPAVHVPGTPGTSG
NSV---------------TPSANSSLSSSGELGQPS------GEQMLQ---A-------R
TKGSA-GT---HSTKPF---SGATPTPFLLAGDR--NPASPVG-SASPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDNIERQLDALEHSGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEFELRCLLNK--PEKDWTDEDRAREKVL
MQELMTLIEQRDAIVNCLDEDR-QREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTIK
VLKFLGNKREAKSKAPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 119)

RA---ALQAWCRRQ-------------CEGYQGV
EIRDLSGSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVYENNRLVSEFPEA-LGR
GARAKGEALLRLQIPAVPARLLPL------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSVEPE--DVVQGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLTE----DA------KDVPGGS------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TLKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEEDEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYGGV
EIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPSYAGISTSRKDL--V--------T-S
S-----------------PPSAAPSPAEPD---DTQSEELSSGSLSER--GAQQAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 291)

C
AACQQHVHLVQRYLAEGRLYHRHCFRCRQCSSTLLPGAYKSGPETGTFVC

ENSGT00760000118856_7_Linker_1_2 (291, 1290)

AERCTRLGPG
GQAGARPVPPSQPK---SQQLAE----AA------RDGEGGS------------------
-PSPSVA---------------A-----G---HKAISE----ARPH---VPTKPPLPGKP
QELS---------SPISGRPTPAPRKASDGMALTP----PTPRPRCSLQQDSTAEQGG--
SGGLVNG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERT--PPPRKEPPWIALVQAEH-KKKPAPLPP-SS-PKPPSRA--S
RQVENGGV-EEVPLR-SPAAGASWEPKPYNPFEEEEEEAEEPSPAA--------------
---------------------------------------------PSPAPSPAQAP-PES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPSASPL------
----ALHT---SRLSHSEPPSATP-------SPALS--VESLASESCS------------
---------------------QTAAGALL---EPP----AVPKSSSEPAVHAPGT---PG
T------------PGNSASLSAHSSLSSSGELVQPS------MEQTPQ---VRT-R----
--GS-PAP---QPVKLC---SGAAPTPLLLVGD--KSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPTV-----------
-------------------------------------------------K----------
------KA----TKG-------PKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIERQLDVLEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGCEDDLLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDKSREKVL
MQEFMTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRRKEFQKEAEPEGKKKGKFKTMK
MLKMLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMKVPDCLSIMTYVSQYYNHFTNPNQARVP--------------------
-----PPMRHP--AAASSPPLPAHKKPVPAVESPPAPQDDVAEGLAER--SQCNTLSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACHKHVHLVQRYLAEGKLYHRQCFRCKECSSTLLPGSYKPGPESGTFVCTQH

ENSGT00760000118856_7_Linker_1_2 (294, 1283)

WGKLGLS
GRTGGRPSPDLEHLSKRIEARAATVGEDVSSSEAEERKEDHVQTPQAIASESHPPEEEEK
GRAPNGAE---M----AASS--VRAENKTPCSEPCSQTP---PRPP---LPSKPLMLSQD
------KASPLDGRLKDTRPTPAPRRSTDAAAPSPPSSNPVPRPRSSMQSEAS---EP--
GLGLVNG---------RVPDPGP-------------------------------------
-------------------------PVPKPRG----------------------------
---------RPTSSDRSGAAVRPKDPPWIALVQAEP-KRKPAPPAP-GSGLGTPT--KAS
EEEEEGKER------EGDSGSVSSESKLYNPFEEEEEEEDEGAASKNTP-----------
-----------------------------------------------------KQDQSES
TTKPIHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
---VHHPI---SRLSHSEPSSSAP-------SPALS--LESINSECSA------------
---------------------KAAGDL-----DEA----SVPKSSSEPMVHVPAASKISC
TDTPLASVSSSESPAAPASLSTNSSS-SSSELVSSSGEAQWGTQQASK---S---FSSSN
LKTSP-SR---LPPKPP---AGASPTPLLLASDM-GEG--SPKDSPSPKPHLKSSCKENP
FN------------------------------------RKS----SPVT-----------
---------------------------------------------SPSAQ----------
------KT----PKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YVPVEDIYGEMDTIEQQLDELEHRGVELEEKLRSVE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NDTPEDSLLVDWFKLI
HEKHMLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PAKDWTADDRERDKVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFHKD--SEGKKKGKFKPMK
VLKLLGNKHESKSKSPKEKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAAS--------------------
-----P-PKPGKDPAPPS-PTSTSPAVQPG--EEAQGDDLSPDSLSEQ--GKQQPPSSA

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
SRSGTRLLSQQRQQPAA---------AE-----A---KD-----------------AEDN
DPSLS--V-----------A--AVAEADR---LQASSE----VQFH---TPTKPPLPSKP
--------QELAS-PPGGRPTPAPRKASESSALTPP----TPRPRSSLQQDGTVEQSV--
SSGLVNG---------RLQ--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERMA--APRKDPPWITLVQTEP-KKKPAPQPP-SSGPGP--LSQAY
RQVEDGGLEEQTQKSS----GTEPEPKPYNPFEEEEEEEGEPAPPVPSP-----------
----------------SLAPPV------------------PSPSPAPPVPSPAP-APSEA
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LAIHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPAVHVPGTPGTSG
NSV---------------TPSANSSLSSSGELGQPS------GEQMLQ---A-------R
TKGSA-GT---HSTKPF---SGATPTPFLLAGDR--NPAPPVG-SASPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDNIERQLDALEHSGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEFELRCLLNK--PEKDWTDEDRAREKVL
MQELMTLIEQRDAIVNCLDEDR-QREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTIK
VLKFLGNKREAKSKAPGDKS-------------

------------------------------------------------------------
---------------------------------

PF00307 // ENSGT00760000118856_7_Domain_0 (94, 152)

DFDSLSKDNVFENNKLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQA-AV--------------------
-----SPPRKD--PAPSSPPSEALTPAEPG--PEAEDKEFPSSSLSER--GAHQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 299)

C
AACHQHVHLVQRYLAEGKLYHRHCFRCRQCSSTLLPGAYRNGPEEGTFVCAEQCARLAPG
ARLGPKSGLPPQP---KQQQLP----EE-----A---RD-----------------TEGD
GRCPGLAE---------------EPEVDV---AKANPE----SRPR---IPTKPRIPSKP
--------QELAS-PPAGRPTPAPRRASESTVLTPP----TPRPRSSLQQESS--EPG--
GSSLATG---------RLH--EP-------------------------------------
-------------------------PIPKPRG----------------------------
---------TPKLSERTP--SPRKEPPWITLVQVEP-KKKPAPLPP-SSSLAP------T
RRIENGSDDGGA---QQNPSAAGLELKPYNPFEEDEEER----PVALSP-----------
------------------------------------------------ATGPAPT-PPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSEGSS------------
---------------------QVPGGTLL---EPP----AVPKSSSEPAVHAPGTSGAS-
--A---------------SLSTNSSLSSSGELVQPS------VDRTSQ---ASP-RLTPS
LRASP-GP---QPAKPC---IGASPTPLLLAGDK--SPVPSPG-TSSPQLQMKSSCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPATK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDIHGEMDTIERQLDALEHRGVQLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------TEGREDALLVDWFRLI
HEKHLLVRRESELIYIFKQQNLE---QHQADVEFELRCLLNK--PEKDWTEEDWGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKK--------------------
---------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMSVPDCLSIMTYVSQYYNHFASPGQADVSPPRKDL--A--------P-C
S-----------------PPSVAPTPAEPG--DGVQGEELS-GSLSEQ--GAHQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACRQHVHLVQRYLVEGRLYHRHCFRCQQCSSTLVPGAYRSGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
VRLGARPGPAQQPKQQHQQQLAE----EA------KDVLGGG------------------
-PSPSVA---------------AGAEADG---PKASPK----ARPQ---IPTKPRVPGKD
PELA---------SPPASRPTPAPRKAPESTAPTP----PTPRPRSSLQQDNSVEQPA--
GSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TLKPSEGT--QAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSGD--S
GQVENGGVVAEVAQP-SPAA--SLEPKPYNPFEEEEEEEEEEESP---------------
-------------------------------------------AAPSLPTSSAPA-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGRELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------SA----ASSLSSSGELVPPS------AAQTPR---DSP-GLAPK
SGDSP-AP---PPAKPC---SGATATPLLLVGD--KCPAPPP-ATSSPQLQLKSSCKENP
FN------------------------------------RKPSPAASPTT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPR-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERQLDALEHRGVLLEEKLRGGS--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDNMLVDWFKLI
HEKHLLVRRESELIYVFKQQSLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMMRKKEFQKEAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

----------------------MSGPRS---ALQAWCRRQ-------------CE

PF11971 // ENSGT00760000118856_7_Domain_0 (56, 132)

GYPGV
EVRDLSSSFRDGLAFCAILHR------HRPDLLDFNSLSKENVYENNRLAFEVAEQELGI
PALLDPSDMVS

ENSGT00760000118856_7_Linker_0_1 (132, 240)

MKVPDCLSIMTYVSQYYNHFNSPSQARIP--------------------
-----PSLKRPAGASAPTLPTHEST---ATSDTTSAPQDDVAEGLAEQ--SQHTTLSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 280)

C
AACQQHVHLVQRYLADGKLYHRQCFRCKECSSTLLPGSY

ENSGT00760000118856_7_Linker_1_2 (280, 1283)

KPGPELGTFVCTQHRGKLGLS
GRAERRPSPDLQYVKESKEPGIVTAGAEEENGI----------------LETHPSAIEER
DKGGKVVDRVEIKIEVPLVQPKNETLASAPDSEPSSQMP---LKPP---VPAKPPMFIQD
------KAK-----LMEPRPTPAPRKSIDTTTVSPPNSHPVPRPRANIQTESCS--EP--
GSGVVNG---------RPSDPCP-------------------------------------
-------------------------PVPKPRG----------------------------
---------RPASSDRTGETPKPKDPPWIALVQGEP-KRKPAPPPP-GGSKESPP--RAS
EEDEDV--AEEGKAQGRESRPTTRKSKPYNPFEDEEEEEIGEEEGSATP-----------
------------------------------------------------QNAPKPEQTEAE
TSRAAHPWYGITPTSS--------------------P-KTKKRPAPRAPNASPL------
---AHHSI---SRISRSEPSSSTP-------SPALS--LESIASECLV------------
---------------------KAAENL-----EEI----SVPKSSSEPMVHDPPASSFN-
--PPLASISSGEGTAALPSGSTVSSLSSSSELADSGNEVPVGNLQTTN---S---CSAGN
LKTSS-EQ---TSPKPL---AGATPTPVLLVSDL-NSGA--ARNSPSPKAQPKSSCKENP
FN------------------------------------RKP----SPVA-----------
---------------------------------------------SPSIK----------
------KN----PKG-------PKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----SDQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YVPVEDIYGEMDSIEQQLDELEHRGVELERKLRSMENV
RER---------------------------------------------------------
---------------------------------------------------------LNC
SS-------------LKRWE---------QDISFISQLHSLGEVMEAPEDGLLVDWFKLI
HEKHMLVRRESELIYIFKQQNLE---QRQADVEFELRCLLNK--PEKEWTDDDRVREKVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFHKETDADNKKKGKFKPMK
VLKLLGNKNESKSKSPKEKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPGQAAAS--------------------
-----P-PKPGKDPAPPS-PTSTPPAVQPG--EEAQGDDLSPDSLSEQ--GNQQPPSSS

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
GRSGTRSLSQQRQQPAAVAAAA----AE-----A---KD-----------------AQDS
DPSLS--V-----------A--AVAEADG---LQASSE----GRLH---TLSKPPLPSKP
--------QELTS-PPVGRPTPAPRKASESSALTPP----TPRPRSSLQQDGAVEQSV--
SSGLVNG---------RLQ--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERMA--TPRKDPPWITLVQTEP-KKKPAPLPP-SSGPGP--VSQAC
RQVEDGGLEERTQKSP----GAEPEPKPYNPFEEEEEEEGEPAPAVPSSAPAPAVPS---
------------------------------------------PAPAPAVPSPVP-ASLET
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LAIHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPAVHVPSTPGISG
NSV---------------PPSANSSPSSSGELGQPS------GEQRPQ---A-------R
TEGSA-GT---HSTKPF---SGATPTPFLLAGDL--NPAPPVG-SASPQPQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------TKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQHIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDNIERQLDALEHSGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQGDVEFELRCLLNK--PEKDWTDEDRAREKVL
MQELMTLIEQRDAIVNCLDEDR-QREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTMK
VLKLLGNKREAKSKAPGDKS-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------GEELSSPSSLSEQ--GTHRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 298)

C
AACRQHVHLVQRYLADGRLYHRHCFRCRQCSSTLLPGAYTNGPEEGTFVCAERCARLGPG
GRLGPRCAPATQSKPLR----------------L---PD-----------------EDAG
DTSPAEGA---G------------AKADD---AKAVPE----ARPQ---LAAKPRLPSKP
--------QELTS-PPGSRPTPAPRKASESSAPTPP----TPRPRSSLQQDSLAEQAG--
GSNLVNG---------RLH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSEXXX--XXXXXXXXXXXXXXXX-XXXXXXXXX-XXXXXX--XXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXX-XX-X-XXXXXX-----------
------------------------------------------------XXXXXXXXXXXX
XXXXXXXXXXXXXXXX--------------------X-XXXXXXXXXXXXXXXX------
---XXLHA---SRLSHSEPPSATP-------SPALS--VESLPSESCS------------
---------------------QAASTQLL---EPP----AVPKSSSEPAVHAPGTPSNS-
--A---------------SLSANSSLSSSGELAQPG-----------------P-SLAPR
TPASP-GP---QPAKPS---SRAAPIPPLPVGDK--NTVPAPG-TSSPQLQVKSSCKENP
FN------------------------------------RKP----SPAA-----------
---------------------------------------------SPATK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDIHGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDLLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRVRDKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQRETESEGKKKGKFKTMK
VLKLLGNKREARSKAPGDRS-------------

------------------------------------------------------------
---------------------------------

PF00307 // ENSGT00760000118856_7_Domain_0 (94, 152)

DFDSLSKDNVYENNRLAFEVAERELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSSQGGGQ--------------------
-----Y------------------------------------ESLAE-----QGIPSSS

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 299)

C
TACQLHVHLVQRYLVEGKLYHRQCFRCKECSSTLLPGAYKNGPEAGTFVCTRHRGKLTSL
GWTEGRPRTAPQHPEQMGQRQLAEDGEDF-------------------------------
---PG--D----------------RE------EPKPSSK---PLPQ---TVSKPPLPSKP
--------QELAS-PPAIRPTPAPRKVSETSASSAP----IPRPRSSVQGESPGEQ----
GGCLVNG---------RVHETSP-------------------------------------
-------------------------PVPTPRG----------------------------
---------TPKASERMS--SSRKDPPWITLVQAEP-KKKPAPLPP-GSRPQTPL--RAS
EEEESR------NRAWPWSQRAGQEPKPYNPFEDEEEDKEAA---AP-------------
-----------------------------------------------------PPSPAEQ
TPKTLHPWYGITPTSS--------------------P-RTKKRPAPRAPSASPL------
----ALHV---SRLSHSEPPSSTP-------SPALS--VESLSSEGSV------------
---------------------LAPGEL-----EPP----SVPKSSSEPTVHGPGAPA---
------------------SLSATSSLSSSEEIAQPSLDQPAS-------------PSASC
AQVTP-GP---QPAKPC---VGAAPTPLLLVAER-S--------PPSPQLQVKSSCKENP
FN------------------------------------RKA----SPMS-----------
---------------------------------------------SPTVK----------
------KT----QRG-------GKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDLYGEMDVIERQLDQLEHRGVALEERLRSGQNX
XXX---------------------------------------------------------
---------------------------------------------------------XX-
---------------------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXFKQQNLE---QRQADVEYELRCLLNK--PDKDWTEEDHGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFHKEADPSMKKKGKFKTMK
VLKMLGNKHDSKSKSPKEKS-------------

------------------------------------------------------------
------------LGLCLQVSR------RRRA

PF00307 // ENSGT00760000118856_7_Domain_0 (92, 151)

LLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHFAGSGPAAGV--------------------
-----SSPRKG--LALSSPPSEASTPADPG--DRAQGEECSPGSLSKQ--GSHRTPSSTC
AACQQHVHLVQRYLVDGKLFHRHCFRKRRCSSTLLPGAYRNGPEEGTFVCAEHCARLGPS
GRSGAMP-----------XQLT----EE-----T---KE-----------------VEGG
SPSPKATA---G------------AEADV---PKASPE----GRPQ---VPPKPRVPGRP
--------QELAS-PPASRPTPAPRKASESTAPTPP----TPRPRSSLQQENLVEQGG--
GSGLVNG---------KLQ--EP-------------------------------------
-------------------------PIPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPP-PGQEG
RQVENGGVDKAA---P-----QGPEPKPYNPFEEEE--EE-P-PAAPSP-----------
------------------------------------------------APGPASTP-LES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSTSPL------
----ALHA---SRLSRSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QPPSEELL---EPP----VVPKSSSEPAVHAPGTPGTS-
--A---------------SLSANSSLSSSGELVQAS------VDRMPQ---ASP-GLAPN
ARGSP-GP---PPAKPC---GDTAPSPLVLVGDK--SPAPSPG-ASSPQLQVKSSCKENP
FN------------------------------------RKP----SPTA-----------
---------------------------------------------SPSVK----------
------KA----TRG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----SDQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEIDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQKEAESEGKKKGKFKTMK
VLKLLGNKRDTKSKCPGDRS-------------

------------------------------------------------------------
---------------------------------DFDSLSKD

PF00307 // ENSGT00760000118856_7_Domain_0 (102, 151)

NIFENNRLAFDVAERELGI
PALLDPSDMVSMRVPDSLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FAAPGQGGGTAGASSP--GSLGVRKVSGGC
LEPAWVAAVPGPCVCLRSPPGASQPSPSPF--KVPGGRQVP-SPPGAAPGDVGLPAGST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 279)

C
AACRQHVHLVQRYLVEGRLYHRHCFRCRQCSSTLLPGA

ENSGT00760000118856_7_Linker_1_2 (279, 1284)

YRSGPEEGTFECAEHCARLGPG
GRLGPRSGPPTQPRPPQ----TT---EET------QDGEAGS------------------
-PGTCVA---------------AGAEADE---PKASPE----ARPQ---ITAKPRVPSKS
QELT---------SPLAGRPTPAPRKAPESPAPTP----PTPRPRSSLQQDGSVEQAG--
SSGLVNGKTLESESGGSLPGPPWGTEALRGLRMGRESWACIPSPASPRFPSPLPWSAAPG
VGAATLEPLPLRGPHWKVLEKRTWFPVPQSQAPTSQPSPGACSPAGGAVLPACLGGGESR
RPLSSLHEWLPLLPPPCRTPAPRKDPPWITLVQAEP-KKKPAPLPP-SGSPAPPRRG--G
QQGESGGAQA-------------LQPLPRRPPAL--------------------------
-------------------------------------------ALPTQ------R-----
----PHPSPCIPGTAS--------------------PPPAAPRPRSALPRERP-------
-----ARPRSASRLSHSEPPSATP-------SPALS--VESLSSESCS------------
---------------------QSGRAQLL---EPP----AVPKSSSEPAVHAPGA-----
-------------PGNSANLSADSSLSSSGELAQPS------VEQTPQ---AGP-SLAPR
TRGGP-GP---QPAKPS---SGVTPTPLSVAGD--RSPAPSP-GTSSPQLQLKAHLGSIS
PP------------------------------------SAAPPPGSTIR-----------
-------------------------------------------------T----------
------PI----HPGQALARVTLRPCPRPPAQSAQGDRQHKCSRRWSDVASGGLPSGG--
--AALWEANTLPALL----HPSH

PF12130 // ENSGT00760000118856_7_Domain_2 (1284, 1594)

IPEEDIHGEMDTIERQLDALEHRGVALEERLRGGG--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEGCEDDMLVDWFRLI
HEKHLLVRRESELIYVFKQQHLE---QRQADVEYELRCLLNK--PEKDWTEEDQLREKVL
MQELVTLIEQRNAIVNCFGRGPAEVEEEEDKMLEAMIRKKG-------------------
---------------------------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFESLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKDL--A--------P-C
S-----------------PPSVAPTPAEPG--DGAQGEELS-GSLSEQ--GAHQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACRQHVHLVQRYLVEGRLYHRHCFRCRQCSSTLVPGAYRNGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
ARLGARPGPPQQPKQQHQQQLAE----ET------KDVLGGS------------------
-PSPSVA---------------AGEEADG---PKASPK----ARPQ---IPTKPRVPGKP
LELA---------SPPASRPTPAPRKASESTAPMP----PTPRPRSSLQQENSVEQPV--
GSGLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPGRD--S
RQVENGGV-AEVAQP-SPAA--SLEPKPYNPFEEEEE---EEESP---------------
-------------------------------------------SGPSLATSPAPA-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------SASLSANSSLSSSGELVQPS------VAQMPP---ASP-GLAPK
TGGGL-AP---LPAKPC---SGATATPLLLVGD--TCPAPPP-GTSSPQLQLKSSCKENP
FN------------------------------------RKPSPAASPTT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQSLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIRKKEFQKEAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
---------------------------------

PF00307 // ENSGT00760000118856_7_Domain_0 (94, 152)

DFDSLSKENVYENNRLAFELAERELGI
PALLDPNDMVSMKVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

NNPSQARVP--------------------
-----P-PMKRP-AAASSPPLLSH-----K--KPVAAAESSSTPQGEG--KGESPSRST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 298)

C
AACQQHVHLVQRYLAEGKLYHRQCFRCKECSSTLLPGSYKPGSEAGTFVCTHHRGKLAVS
GKMDRRASPERSRGGKGQQHCC----G-----------------------------ERGG
DPDACREA---G-------Q--PGGEGQH---LQQSPDS---DAPP---LPSKPSAPSQD
------KASPLDARLRDTRPTPAPRRQGEGSDCAPG----LVNERLSMCRSGVVTVCP--
SVFLGRG---------PEP--SP-------------------------------------
-------------------------PVPKPRG----------------------------
---------RPCSSDRAGAAARAKDPPWMALVQAEP-KKKPAPPPP-PPPGSGHEPP---
---SMGK-AK-----SEESKPDAAEPKPYNPSAQKSTPEQ--------------------
-------------------------------------------------------EQGEA
AAKSLHPWYGITPTSS--------------------P-KAKKRPAPRAPTHQPF------
-----------SRLSHSEPSSSAP-------SPALS--LESIHSESSS------------
---------------------PDTPLASVSSSESP----AAP------------------
--A---------------SLSTTSELAGCGGEAQPG------APHASR---SI---SAGS
LKTSP-SR---LPPKPPAXRETGEPTPNLSSWDA--VPLPDPHTSSPFVLSLQSSCKENP
FN------------------------------------RKP----SPAA-----------
---------------------------------------------SPSAK----------
------KP----PKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----TDQYIPEEDIYGEMDAIEHQLDQLEHRGVALEEKLRSAE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NDSPEDSLLVDWFKLI
HEKHMLVRHESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRVREQVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFHKETEAEGKKKGKFKPMK
VLKLLGNKHDSKSKSPKEKS-------------

---------------------------------------R-------------DGGY

PF00307 // ENSGT00760000118856_7_Domain_0 (58, 152)

RGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSVEPE--DVVQGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLTE----DA------KDVPGGS------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TLKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEEDEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

------------------------------------------------------------
---------------------------------

PF00307 // ENSGT00760000118856_7_Domain_0 (94, 152)

DFDSLSKDNIFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

CSPGQA-GM--------------------
-----SSPRKG--LAPSSPPSEAVTPVEPG--DEAQDEKLSTGSLSEQ--GTQQAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 298)

C
AACQQHVHLVQRYLADGKLYHRHCFRCRQCSSTLLPGAYKKGPEEGTFVCAEHCARLGPG
SWLGTRPGPPSQSKHQHQPPPA----EE-----A---KD-----------------VEGS
YPSPHVAA---V------------AEADG---PKDSPE----ARPH---MPSRPRVPSKP
--------QELAS-PPASRPTPAPRKTSENTPPTPP----TPRPRSSLQHENVVEQGG--
SGSLVNG---------RPH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERTP--AHRKDPPWITLVQAEP-KKKPAPLPP-SSSPELPG----R
RQVENGGIEDVAPKSP----VAILEPKPYNPFEEEEEEES---LAASSL-----------
------------------------------------------------ATGPSP-VHPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPGASPL------
----APHT---SRLSHSEPPSSSP-------SPALS--VESLSSEGSS------------
---------------------QTTGRELR---KPP----V--KSSSEPGVHAPGPPGRP-
--A---------------ALSASPV--ISGELGQPS------TDRPPQ---ASR-SS-AS
ARGSP-SP---QTAKPP---SGTAPTPLLLVGDR--SPAPSSG-TSSPQLQVKSSCKENP
FN------------------------------------RKA----SPAA-----------
---------------------------------------------SPTTR----------
------KA----TKG-------PKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDIYGEMDTIERQLDALEHRGVQLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NESREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QXXXXXXXXXXXXXXXXXFQKEAESESKKKGKFKTMK
VLKLLGNKRDTKSKSSGHKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYSGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMNVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAVA--------------------
-----P-PTPAKDPAPPS-PTSASPAVKPG--EDTQGDDLSSDSLSEQ--GKQQPPSSV

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLLPGSYISGLEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
GRSGTRPLPQQKQQQVAE---------E-----A---KD-----------------GEES
DPSPSVAE---V------------AKADG---LQPSSE----VQPQ---TLNKPPLPSKP
--------QEVAS-PPVGRPTPAPRKASENSALTPP----TPRPRSSLQQDGLVEQGV--
STGLVNG---------RLQ--EP-------------------------------------
-------------------------PIPRPRG----------------------------
---------TPKLSERMP--APRKDPPWITLVQTEP-KKKPAPLPP-S-----NSPGPLS
RHVENGGLEERTQKSP----VSEPDPKPYNPFEEEEEEEES-APAVP-------------
------------------------------------------------GPVPAP-APPES
TPKPLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LVLHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPAVHMPGTPGTSG
NSV---------------TPSANSSLSPSGEQGQPS------GEQMPQ---A-------R
TRGSP-ST---QATKPC---SGATPTPFLLAGDR--SPAPSLG-SSSPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPM-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDNMLVDWFKLI
HEKHLLVRRESELIYVVKQQNLE---QRQADVEFELRCLLNK--PEKDWTEEDRAREKVL
LQEFMTLIDQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQREAESEGKKKGKFKTMK
MLKLLGNKRDTKSKVPGDKS-------------

--------------------------------MCGWCLPRLTDEKMGPEGPLTCAGHRAL
PGRDLLLSDFSPAPLPPLLTNLP----LFASRRDFDSL

PF00307 // ENSGT00760000118856_7_Domain_0 (99, 152)

SKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPSQASVSPPRKDL--A--------A-S
S-----------------PPSEAPIPAEPG--DETQNEELSSGSLSER--GAQRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 290)

C
AACQKHVHLVQRYLAEGKLYHRHCFRCRQCSSTLLPGAYRSGPEEGTFV

ENSGT00760000118856_7_Linker_1_2 (290, 1290)

CVERCTRLGLG
GQAGARPGPPSQPK---PQQLTE----EA------RDGEGGG------------------
-PSPSVA---------------A-----G---PKAITE----ARPH---VPTKPPLPGKP
QELV---------SPPSSRPTPAPRKTSDCVASTA----PTPRPRSSLQQDSTAEQGG--
SGGLANG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERM--PPPRKDPPWITLVQAEP-KKKPAPLPP-GS-PGPPSRA--S
RQVENGGV-EEMPQC-GPAAGASLEAKPYNPFEEEE-ETEEPSPAV--------------
---------------------------------------------PSPASSPAQAP-PEC
TPKSLHPWYGITPTSS--------------------P-KAKKRPAPRAPSTTPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLASESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAP------G
T------------PGNSASLSAHSSLSLSGELVQPS------VERTPQ---ARI-R----
--DS-PGP---PPAKPY---SGATPTPLLLVAD--RSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPTA-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEGHEDDMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDKNREKVL
MEELMTLIEQRNAIVSCLDEDR-QREEEEDKMLEAMIKRKEFQKEAEPEGKKKGKFKTMK
MLKMLGNKRDTKSKSPGDKS-------------

-------------------SPQLQGHMGIQPSEATWPAH---------------------
------ASARLSLVVRAAV--FS----HRRAR

PF00307 // ENSGT00760000118856_7_Domain_0 (93, 152)

LDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSIPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPAEPE--DVAEGEELSSGSLLEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACHQHVHLVQRHLAEGRLYHRHCFRCRRCSSTLLPGAYKNGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
ARSGTRPGSFPQPKQQHQQQLAE----DA------KDAPGGG------------------
-PSSSAP---------------AGAEADG---PKASPD----ARPQ---IPTKPRVPGKP
QELS---------SPPAGRPTPAPRKASESTTPAP----PTPRPRSSLQQENLVEQAS--
SSSLMNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWIMLVQAEP-KKKPAPLPP-SSSSGPPSQD--S
RQVDNGGT-EEVAQP-SPAA--SLEPKPYNPFEDEEN-EEEEAPAA--------------
---------------------------------------------PDLATRPAVA-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPGASPL------
----GLHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVGLSANSSLASSEELVQPR------VEQMPQ---ASP-GLAPR
SRGSP-GP---QLAKPC---SGATPTPLLLVGE--RSPVPSP-GSLSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGM--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPRDKS-------------

------------------------------------------------------------
-----------------MPVQ------SFRQERDFDSLSK

PF00307 // ENSGT00760000118856_7_Domain_0 (101, 151)

DNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYHH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FASPGQ-AGV--------------------
-----SSPGKA--QAPSSPPSEAPTPAEPG--DRAQGEELSSGSLSEQ--GAQRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACQQHVHLVQRSLVEGKLYHRHCFRCRQCSSTLLPGAYKSGPEEGTFVCAE

ENSGT00760000118856_7_Linker_1_2 (293, 1283)

HCARLGPG
GRSGATSGPPLQP---KQQQLA----EE-----V---KD-----------------VDGG
GVGRSAPA---G------------AEADV---PKASPE----ARPQ---IPTKPPLPSKA
--------QELGSSSPAGRPTPAPRKAPESPALTPP----TPRPRSSLQHENLAEQGG--
SSGLVNG---------RLH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-RKKPAPLPP-SSSPGP--PSREG
RRVVNGGTEESQGQEEQSQVPAGPEPKPYNPFEEEEEEEE-S-PAAPSP-----------
------------------------------------------------AAGPALAHSAEV
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHT---ARLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTPSGELL---EPP----AVPKSSSEPAVHAPGTPGTS-
--A---------------SLSTHSSLSSSGELVQPS------ADQIPQ---AGP-GLAPS
TRGSP-GP---QPAKPC---SGAAPTPLLLVGDK--SPVPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPTTK----------
------KT----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTDEDRGREKVL
MQELMALIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRRKEFQKEAEPEGKKKGKFKTMK
D--------------------------------

--------------------XXXXX--X---XXXXXXXXX-------------XXXXXXX
XXXXXXXXXXXXXXXXXXX--XX----XXXXXXDFDSL

PF00307 // ENSGT00760000118856_7_Domain_0 (99, 152)

SKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPDQAGVSPPRKDL--A--------P-C
S-----------------LPSVAPTPVEPG--DGAQAEELSPGSLSEQ--GTHRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLAEGKLYHRHCFRCRRCSSTLVPGAYRSGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
VRSGTRSGPHLQLKQQHQQQLAE-----A------EEVPGGG------------------
-PSSSAP---------------VGAEADG---PKASPE----ARPQ---IPTKPLVLGKP
QELA---------SPPAGRPTPAPRKASESTAPTP----PTPRPRSSLQQENLVEQAG--
GSGLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSEGT--PAPRKDPPWISLVQAEP-KKKPAPLPP-SSSPGPPRRD--S
ERVEDRGV-EEGAPC-SPAA--GLEPKPYNPFEEEEE--EESSTAV--------------
---------------------------------------------PSLATSPALV-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHT---SRLSHSEPPSATP-------SPALS--VESLSSDSPS------------
---------------------QTAGGKLL---EPP----AVPKSSSEPAVHAPDT---PG
N---------------PASLSADSSLSSSGELVQPS------VERTPQ---ASP-GLAPR
TRGSP-GP---PPAKPC---SGATPTPLLLVGD--RSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPTT-----------
-------------------------------------------------K----------
------KA----TKG-------SRPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFQKEAELEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

-------------------------PRG--

PF00307 // ENSGT00760000118856_7_Domain_0 (31, 151)

-ALKAWCRRQ-------------CEGYRGV
EIRDLSTSFRDGLDFCAILHR------HRPDLLDFDSLSKDDVYENNRLAFELAERELGI
PALLDPNDMVSMKVPDRLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FNNPSQASVPLPMKRP--AAA-SPPL----
----LSQKTPVAAIESPSAPQ----------------DDP------PSERSQRSTLSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACQQHVHLVQRYLAEGKLYHRQCFRCKECSSTLLPGSYKPGSEAGTFVCTQ

ENSGT00760000118856_7_Linker_1_2 (293, 1283)

HRGKLAVS
GKAERRPSLDRQSPEE--------------------------------------SVAETS
TPAEGLAGPAE------KDSTASKAETPTPPAHAGSGP----PVSQ---TPPRPPIPSKP
AGLTQDKASSLDGR----RPTPAPRKATDGSALSPPTSHPVPRPRSTLQGEGSEC-----
GPGMVNG---------RLPETSP-------------------------------------
-------------------------PVPKPRG----------------------------
---------RPCSSDRGGAAARAKDPPWMALVQAEP-KKKPAPPPPPGNSHETPSRTSEE
EDGEEVRK----ARS-EESRSDSAEPKPYNPFEEEDEEEVESADTQK-------------
-------------------------------------------------STPE-QEQSET
AAKPLHPWYGITPTSS--------------------P-KAKKRPAPRAPNASPL------
----AHHP--ISRLSHSEPSSSTP-------SPALS--LESINSESSA------------
---------------------KVLGD--T---DEA----SVPKSSSEPTVHMPA------
-----------ESPAVPASLSTNSSFSSSSELASLS------GETQPSTLHTSR-SISTG
SLKASPSQ---LPPKPP---AGASPTPILLASDGGA---GSPKTSSSPKPQLKSSCKENP
FN------------------------------------RKPSPAASPSA-----------
-------------------------------------------------K----------
------KP----PKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----TDQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEENIYGEMDAIEHQLDELEHRGVALEEKLRSAE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NDNPEDSLLVDWFKLI
HEKHMLVRHESELIYIFKQQNLE---QRQSDVEYELRCLLNKP-VEKDWTDEDRGREKVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFHKETETESKKKGKFKPMK
VLKLLGNKHDSKSKSPKEKS-------------

-----------------MAAFQLQGVGH---LNRRWRRGA-------------WVSLPS-
------CGV--GDGGCEN---FQ----LSGALGDFDSL

PF00307 // ENSGT00760000118856_7_Domain_0 (99, 152)

SKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSAEPE--DVAQGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGSRPGPFSQPKQQHQQQLAE----DA------KDVPGGS------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPQVPGKP
QELA---------TTPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLESKPYNPFEEEEEDEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVGLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------I------VEQTPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 151)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FCSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPVEPE--DVAQGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGG------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKL
QELA---------SPPAGRPTPAPRKASESTTPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEL---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPTA--SLESKPYNPFEEEEEDKEEEAPAA--------------
---------------------------------------------PSLATSPALG-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESAS------------
---------------------QTAGAELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSS-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 151)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FCSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPVEPE--DVAQGEDLSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGG------------------
-PSSSAP---------------AGAEADG---PKARPE----ARPQ---IPTKPRVPGKL
QELA---------SPPAGRPTPAPRKASENTTPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEL---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TLKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--G
RQVENGGT-EEVAQP-SPAA--SLESKPYNPFEEEEEDKEEEAPAA--------------
---------------------------------------------PSLATSPALG-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESAS------------
---------------------QTAGAELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSS-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------HCGPSG---RVL----GQ-------------CSE----
--------FSWHLAIISFFFDLF----LPASCRDFDS

PF00307 // ENSGT00760000118856_7_Domain_0 (98, 152)

LSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMRVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPGQAGVSPPRKDL--P--------SSP
S-----------------SPPMAPTAVEPE--DDAQGEELS-GSLAEQ--GLHRVPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
MACGKHVHLVQRYLAEGRLYHRHCFRCCQCSSTLLPGAYRNGLEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CTRLGPG
ARAGSRPGSLLQTKQPQ----ST----EA------KENDGGG------------------
-SSPRAP---------------AGAAADA---PKVSTE----ARPQ---VPTKPLIPGKS
QELA---------SPPVARPTPAPRKASESIAATP----PTPRPRSSLQQDGSAEQSGS-
SGGLVNG---------RLQDP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSERS--PAPRKDPPWITLVQTEP-KKKPAPLPP-SSSPGPPGQA--S
RQVENGSV-EDGAQQ-SPAA--GPEPKPYNPFEEEEEEEEVPAPVV--------------
---------------------------------------------PSSAPSPAPA-PSES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLASESCS------------
---------------------HTASTELL---ETP----AVPKSSSEPAVHAPSA---PG
T------------PANSASPSANSSLS-SGELTPPG------GERAPQ---ART-S----
-----PGS---QLAKPC---IGATPTPLVLAGD--KSPVPS-LGSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------TKPC-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDSIERQLDALEHHGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------PEGHEDDMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---KRQADVEYELRCLLNK--PEKDWTEEDWGREKVL
MQEIVTLIEQRNAIINCLDEDR-QREEEEDKMVAAMMKKKEFQKEAEPEGKKKGKFKSMK
MLRLLGNKRDAKSKSPRDKS-------------

----------------------MSGPRG--

PF00307 // ENSGT00760000118856_7_Domain_0 (31, 152)

-ALQAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVYENNRLAFELAERELGI
PALLDPNDMVSMKVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

NNPDQARVPPPMKRP--AAAASPPL----
----LAHKKPVATGEQLVAPTLSSP-------RVPSQDDAPVEP-VE--PSQRTTLSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACQQHVHLVQRYLAEGKLYHRQCFRCKECCSTLLPGSYKPGSEAGTFVCTQ

ENSGT00760000118856_7_Linker_1_2 (293, 1290)

HRGKLVMS
GKMDRRPSLDQQSPELRTEAGASSVGEDTLPAGAEVGKDNGSV--EE-TVAET------Q
MPAEVPTSPEE------KDGTPSRAETAIP--HAESGA----PISQ---IPPRPPLPSKP
SVPSQDKAGSLDGQHRHTRPTPAPRRSTD--ALSPPASHPVPRPRSTIQGEASDS-----
GPGMVNG---------YLNP-VP-------------------------------------
-------------------------LSQNPEG---DPAP----LIGSLSFRVCKEFG---
---------GFRKAEGAGAAARAKDPPWMALVQAEP-KKKPAPP-PPGSSHETPSRTLEE
EDGEEVGK----ARS-EENRSDATEPKSYNPFEEEDDEEEESTAPQK-------------
-------------------------------------------------STPE-QEQSET
AAKPLHPWYGITPTSS--------------------P-KVKKRPAPRAPNASPL------
----AQHP--VSRLSHSEPSSSTP-------SPALS--LESINSESSA------------
---------------------KVLGD--T---DEA----SVPKSSSEPTVHTPTATKTSH
TDTPLTSISSSKSPAAPASLSTNSSFSSSSELASFS------GEVQNSTPHASR-SISAG
SLKTSPSR---LPPKPP---AGTSPTPILLASEGGT---GSPKPSSSPKPQLKSSCKENP
FN------------------------------------RKPSPVASPSA-----------
-------------------------------------------------K----------
------KP----PKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----TDQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIEHQLDQLEHRGVILEEKLRSSE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NDSPEDSLLVDWFKLI
HEKHMLVRHESELIYIFKQQNLE---QRQADVEYELRCLLNKP--EKDWTEEDRVREKVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFHKEAETESKKKGKFKPMK
VLKLLGNKHDSKSKSPKEKS-------------

-----------------------------------------------------------I
AGADF---------ELSILHLHFHLPGIIGKAGDFDSL

PF00307 // ENSGT00760000118856_7_Domain_0 (99, 152)

SKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNYF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

ASPGQGGISPPRKDL--A--------P-S
P-----------------PPSATPTVAEPG--DKGQGKELPPGSLSEQ--APQRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACQQHVHLVQRYLAEGRLYHRHCFRCRRCSSTLLPGAYRSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
GWPGTRPGPPSQPK---QQQLPE---EAK------HGGEGGC------------------
-LSPSVA---------------AGPEAEG---PKASPE----ARPQ---IPTKPPVPGKP
QELA---------SPPASRPTPAPRKSSESTALTP----PTPRPRSSLQQDSPVEQGD--
-SGLVNG---------RLQDP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLIDRT--PAPRKDPPWITLVQAET-KKKPAPLPP-SSSPGPPSLALAS
RQAENGAMVE------------GPEPRPYNPFEEDEEEEESLP-AV--------------
---------------------------------------------PSPVPGPALA-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPSSSPL------
----TLHA---SCLSRSEPPSATP-------SPALS--VESLSSQSSG------------
---------------------QAASAELL---EPP----AVPKSSSEPAVHAPDT---PG
T------------PGSSASLSADSSLSSSGETVQPS------TERTPQ---ART-R----
--GS-PSP---LPAKPC---SGATPTPLLLVGD--RSPAPSP-GSASPQLQVKVSVHPHS
------------------------------------------PSASSPG-----------
------------------------------------------------------------
-------------------------I-SLS-----------------------RGGHG--
-----VW----GQVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMSIPDCLSIMTYVSQYYHHFSSPGQAGISPPRKGL--A--------P-C
S-----------------PPSVAPTPAEPE--DVAEGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACHQHVHLVQRHLAEGRLYHRHCFRCRRCSSTLLPGAYKNGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
VRSGTRPGSFPQPKQQHQQQLME----DA------KDAPGGG------------------
-PSSSAP---------------AGAEADG---PKASPG----ARPQ---IPTKPRVPGKP
QELA---------SPPAGRPTPAPRKASESTAPAP----PTPRPRSSLQQENPAEQASSS
SSSLMNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EAVAQP-SPVA--SLEPKPYNPFEDEEN-EEEEAPSA--------------
---------------------------------------------PDLAPSPALA-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------RTAGGELL---EPP----AVPKSSSEPAVHVPGT---PG
N---------------PAGLSANSSLASSEELVQPR------VEQMPQ---ASP-GLAPR
TRASP-GP---QLAKPC---SGATPTPLLLVGE--RSPMPCP-GSLSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGM--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGHEDGMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPRDKS-------------

GRRPGTSRDPTPESEPAGPARVMAGPWG---ALLAWCRRQ-------------C

PF11971 // ENSGT00760000118856_7_Domain_0 (55, 132)

EGYRGV
EIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVS

ENSGT00760000118856_7_Linker_0_1 (132, 240)

MSVPDCLSIMTYLSQYYNHFASPSQAGAPQQYESS--------------
-------------------------KEGSS--QKPEGKKLSSGSLSEQ--GAHQAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLAEGRLYHRHCFRCQQCSSTLVPGSYRSGPEEGTFVCAEHCARLGPG
TRA---------------------------------------------------------
----------------------AGAEEDG---PKGSPE----ARPQ---IPMKPRVPDKP
PELA---------SPPAGRPTPAPRKAIESAAPAP----PTPRPRSSLQQENLGEQAG--
NSGLVNGEPGSRPR--RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSEGY--VN---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAAS--------------------
-----P-PKPGKDPAAPS-PTSTSPAVQPG--EEAQGDDLSPDSLSEQ--GKPQPPSSA

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGLG
GRSGTRPLSLQKQQPAAAA--------E-----A---KD-----------------GEDS
DLSKS--V---V-------V--VAAEADG---LQASSE----VQPH---TLTKPPLPSKP
--------QDLAS-PPVSRPTPAPRKASESSALTPP----TPRPRSSLQQDGMVEQSV--
SGDLVNG---------RLQ--EL-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERMT--APRKDPPWITLVQTEP-KKKPAPLPP-SSGPGP--LSQAS
RQVENGGLEEKTQKSP----AAEPEPKPYNPFEEEEEEEEASVPAV--------------
-------------------------------------------------PSPAP-APPET
TPKSLHPWYNITPTSS--------------------P-KTKKRPAPKAPSASP-------
---LVLHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANTEPS---EPP----AVPKSSSDPAVHVPGTPGTSA
NSV---------------TPSAHSSLSSSGELGQPS------GEQMPQ---A-------R
TRGSP-GT---HSTKPF---SGATPTPFLLAGDQ-KSPAPPMG-SSSPQMLIKSSCKENP
FN------------------------------------RKP----SPST-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDSIERQLDALEHSGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEFELRCLLNK--PEKDWTDDDRAREKVL
MQELMTLIEQRDAIVNCLDEDR-QREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTMK
VLKLLGNKRDAKSKAPTGKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAVS--------------------
-----PSPSPGKDPALSS-PPSASPAVQPG--EEAQGDDLSSASLSEQ--GKQQPPSSA

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLLPGSYNSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
GRSGTRPLSQRKQQQLAE---------------A---KD-----------------GEES
DL--SVSA---V------------AEADG---FQASSE----VQPQ---TPNKPLLPSKP
--------QELAS-PPAGRPTPAPRKASESSALTPP----TPRPRSSLQQDGLVEQGT--
SSSLVNG---------RLQ--EP-------------------------------------
-------------------------PVPRPRG----------------------------
---------TPKLSERMP--APRKDPPWIALVQTEP-KKKPAPPPP-S-----SSPGSPS
RQVENGGLEERTQKSP----VAGPEPKPYNPFEEEEEEEET-APAVP-------------
------------------------------------------------GPA--P-APPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LVLHT---SRLSHSEPPSATP-------SPALS--VESLASESSS------------
---------------------HTASAEPL---ETP----AVPKSSSDPAVHVPGTPGIAG
NSV---------------TPSANSSLSSSGELGQPG------GEQVPQ---A-------R
TRGSP-GT---QATKPF---SGATPTPFLLAGDR--SPAPSRG-SSSPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPAVR----------
------KA----TKG-------AKPM-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDNMLVDWFKLI
HEKHLLLRRESELIYVVKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMMRKKEFQRETESEGKKKGKFKTMK
VLKLLGNKRDTKSKVPGDKS-------------

------------------------------------------------------------
---------------------------------DFDSLS

PF00307 // ENSGT00760000118856_7_Domain_0 (100, 151)

KDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FCSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPVEPE--DVAQGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGG------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKL
QELA---------SPAAGRPTPAPRKASESTTPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEL---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-GSSPGPPNQD--G
RQVENGGT-EEVAQP-SPAA--SLESKPYNPFEEEEEDKEEEAPAA--------------
---------------------------------------------PSLATSPALG-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESAS------------
---------------------QTAGAELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSS-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1613)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--P---------------
----------------------------------------EFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

-------------------------------------R

PF00307 // ENSGT00760000118856_7_Domain_0 (39, 151)

RQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FCSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPVEPE--DVAQGEDLSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGG------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKL
QELA---------SPPAGRPTPAPRKASENTTPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEL---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TLKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQN--G
RQVENGGT-EEVAQP-SPAA--SLESKPYNPFEEEEEDKEEEAPAA--------------
---------------------------------------------PSLATSPALG-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESAS------------
---------------------QTAGAELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQMPQ---ASP-GLAPR
TRGSS-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYGGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPSQASVSPPRKDL--A--------A-S
S-----------------PPSEAPIPAEPG--DETQNEELSSGSLSER--GAQRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 290)

C
AACQKHVHLVQRYLAEGKLYHRHCFRCRQCSSTLLPGAYRSGPEEGTFV

ENSGT00760000118856_7_Linker_1_2 (290, 1290)

CVERCTRLGLG
GQAGARPGPPSQPK---PQQLTE----EA------RDGEGGG------------------
-PSPSVA---------------A-----G---PKAITE----ARPH---VPTKPPLPGKP
QELV---------SPPSGRPTPAPRKTSDSVASTA----PTPRPRSSLQQDSTAEQGG--
SGGLANG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERM--PPPRKDPPWITLVQAEP-KKKPAPLPP-GS-PGPPSRA--S
RQVENGGV-EEMPQC-GPAAGASLEAKPYNPFEEEE-ETEEPSPAV--------------
---------------------------------------------PSPASSPAQAP-PEC
TPKSLHPWYGITPTSS--------------------P-KAKKRPAPRAPSTTPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLASESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAP------G
T------------PGNSASLSAHSSLSLSGELVQPS------VERTPQ---ARI-R----
--DS-PGP---PPAKPY---SGATPTPLLLVAD--RSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPTA-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEGHEDDMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDKNREKVL
MEELMTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFQKEAEPEGKKKGKFKTMK
MLKMLGNKRDTKSKSPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYGGV
EIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPSQGGVSPSRKDL--A--------T-S
P-----------------PPSAVPSPAEPG--DDTQSKELSSGSLSEQ--GTQRAPSSI

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 291)

C
AACQQHVHLVQRYLAEGRLYHRHCFRCRQCSSTLLPGAYKSGPETGTFVC

ENSGT00760000118856_7_Linker_1_2 (291, 1290)

AERCTRLGPG
GQAGTRPGPPSQPK---PQQLAE----EP------RDGEEGG------------------
-STPSVA---------------T-----G---RPAIPE----ARPH---VPTKPPLPGKP
QELS---------SPVSGRPTPAPRKASDSMAPTP----PTPRPRSSLQQDSTADQGG--
SGGLVNG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERT--PPSRKEPPWIALVQAEP-KKKPAPLPP-SS-PRPPSRA--G
RQVENGGL-EEAPQH-SPAAGASCEPKPYNPFEDEEEEAEEPSPAA--------------
---------------------------------------------PSPAPSAAQAPPPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPSASPL------
----VLHA---SRLSHSEPPSATP-------SPALS--IESLASESCS------------
---------------------QTAAGELL---EPP----AVPKSSSEPAVHAPGT-----
-------------PGNSASLSAHSSLSSSGELVQPS------TERVPQ---TRT-T----
--GS-SGS---QPAKPC---SGAAPTPLLLVGD--KSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAA-----------
-------------------------------------------------K----------
------KA----TKG-------PKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIERQLDALEHRGVLLEGKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------HEGREDDMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRSREKEL
MRELMTLIEQRNAIVTCLDEDR-QREEEEDKMLEAMIRRKEFQKEAEPEGKKKGKFKTMK
MLKMLGNKRDTKSKSPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 112)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLVS

ENSGT00760000118856_7_Linker_0_1 (112, 240)

SWTDGSPR-
-------------SSVCVCV--------WPLSHLLAAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSAEPE--DVAQGEELSSGSLSEQ--ATGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLPE----DA------RDVPGGS------------------
-PSSSAS---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEEDEQEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----VWPE---SISSPSL---SCS-------LNVLS--IGVLSA-ARG------------
---------------------SRKGGVCL---NPN----SVTVAA------VPER---PG
L------------SPGPQRRLACLLLASPWEL--SR------NKRLKA---TAL-ALPPG
TRGMPRSP---SQAKPC---SGATPTTPLSVGLGDRSPCAFPWKSRSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MA

PF00307 // ENSGT00760000118856_7_Domain_0 (25, 152)

GPRV---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLXXXXXXXXXXXXXXXXAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHFASPGQ-XXX--------------------
-----XXXXXX--XXXXXXXXXXXXXXXXX--XXXXGDECSSGSLSEQ--GAHRTPSSTC
AACQQHVHLVQRYLADGKLYHRHCFRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX----XX-----X---XX-----------------XXXX
XXXXXXXX---X------------XXXXX---XXXXXX----XXXX---XXXXXXXXXXX
--------XXXXX-XXXXXXXPAPRKASESTALTLP----TPRPRSSLQQENLVEQGG--
GSGLVNG---------KLH--EP-------------------------------------
-------------------------PIPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPPPGRDS
RQVENGGVHEV----------AGPEPKPYNPFEEEQ--EE-P-PAAPRA-----------
------------------------------------------------ATGPAPT-HPES
TPKSLHPWYGITPTSS--------------------P-RTKKRPAPRAPSASPL------
----ALHT---SRLSHSEPPSATP-------SPALS--VESLSSESSG------------
---------------------QPPSGEPL---EPP----VVPKSSSEPAVHAPGSPGTS-
--A---------------SLSANSSLSSSGELVQPS------VDRTPQ---ASP-GLAPN
TRGSP-GP---PPAKPC---SGAAPTPLVLVGDK--SPAPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPTVK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDIHGEMDTIERQLDTLEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------DEGREDDMLVDWFRLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRVREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQKEAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

-------------------------------GSQLSCPPE-------------CWGFRCV
SP------------WPPLLNRPP----LFASHRDFDS

PF00307 // ENSGT00760000118856_7_Domain_0 (98, 152)

LSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPGQAGVSPSRKEL--T--------A-S
S-----------------PPLVAPSPAEPG--DETQSEELSSGSLSEQ--GAQRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 291)

C
AACQQHVHLVQRYLAEGRLYHRHCFRCRQCSGTLLPGAYKSGPEAGTFVC

ENSGT00760000118856_7_Linker_1_2 (291, 1290)

AERCTRLGPG
GQAGARPGPPSQPK---PQQLAE----EA------RDGEEGG------------------
-PSSSVA---------------A-----G---RKAVPE----ARPH---VPTKPPLPGKP
QELS---------SPVSGRPTPAPRKASDSMAPTP----PTPRPRSSLQQDSTAEQGG--
SGGLVNG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERT--PPARKDPPWITLVQAEP-KKKPAPLPP-GS-PRPPSRG--S
RQEENGTV-EEVTPR-GPAAGS--EPRTYNPFEDEE-EVEEPSPAA--------------
---------------------------------------------PSPAPSPAQAP-SEC
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLASESCS------------
---------------------QMAAGELL---EPP----AVPKSSSEPAVHAP------G
T------------PGNSASLSAHSSLPSSGELVQPS------VEQTPQ---ART-S----
--GS-PGP---QPAKPC---SGAAAPP-LLVGD--RSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPTA-----------
-------------------------------------------------K----------
------KA----TKG-------PKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEGREDAMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDKSREKVL
LQELMTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFQKEAESEGKKKGKFKTIK
VLKMLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
---------------------------------DF

PF00307 // ENSGT00760000118856_7_Domain_0 (96, 152)

QSLSKDNVFENNRLAFEVAERELGI
PALLDPTDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SGPGHAGVS--------------------
-----P-PRKD--LAPPPSPPEAAIPVEPG--DSTQDGEHSSGSLAEQ--GAHRPPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 298)

C
AACQQHVHLVQRYLAEGKLYHRHCFRCRQCSSTLVPGAYKSGPEEGTFVCTEHCARLGPG
ARSGAKPGPLEPPKQLQP-QLG----EE--------------------------------
------------------------------------------------------------
-------------------------------------------------------ASG--
VRGGHPS---------RLQ--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPQPP-SSSPEPPS----R
RRVENGATEEC---------PTSLEPKPYNPFEEEEGGEQEP-PAVPSP-----------
----------------------------------------------------AP-AHKES
TPKSLHPWYGITPTNS--------------------P-KTKKRLAPRAPSTSPL------
----VVHT---SRLSHSEPPSSAP-------SPALS--VESLTSEGSS------------
---------------------QTTGGELP---EPP----LVPKSSSEPAVHAPSTPGSS-
--A---------------SPSAHSSLSSSGELAQPS------AEQMPQ---AGP-SLTTD
TRGSP-GA---QAAKPC---TGAAPTPLVLVGDR--SPALTPR-TSSPQLQVKSSCKENP
FN------------------------------------RKA----APTA-----------
---------------------------------------------SPSTR----------
------RA----AKS-------PKPA-RPP-----------------------APRHS--
--FPLIK----RKVQ----ADRYIPEEDIHGEVDAIERQLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDAMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQAEVEYELRCLLNK--PXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX---------X---------------------------X
XXXXXXXXXXXXXXXPGDKS-------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMSVPDCLSIMTYVSQYYNHFASPGQ-AGV--------------------
-----SPPRKG--LALSSPPSETPALSEPG--GGAQAEELSSGSLSEQ--GACRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACHQHVHLVQRYLAEGKLYHRHCFRCRQCSSTLLPGAYRSGPEEGTFVCAE

ENSGT00760000118856_7_Linker_1_2 (293, 1283)

HCTRLGPA
GRLGAKRGLPPQP---KQQQLT----EE-----A---ND-----------------VEGS
SSHPSAAA---G------------AEVDE---PKASPE----ARPQ---IPTKPQLPGKP
--------QELAS-PPASRPTPAPRKASENTAPTPP----TPRPRSSLQHENL-EQGS--
SSGLVNG---------RLH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERVP--APRKDPPWITLVQAEP-KKKPAPLPP-SSSPRP--PRRDS
RQGENGGPEEAA---QGSPAAACPEPKPYNPFEEEE--EE-P-PATPSL-----------
------------------------------------------------APGPGLAP-AES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTPTGELL---EPP----VVPKSSSEPAVHAPGTPGTS-
--T---------------SISANSSLSSSGELVQPS------VARMPQ---ASP-GLAPS
ATGSP-GP---QPAKPC---SGAAPTPLLLVGDK--SPVPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPTTK----------
------KV----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIYGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQHLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRRKEFQKEAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSIPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPAEPE--DVAEGEKLSSGSLSEQ--GTGQTPSSM

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACHQHVHLVQRHLAEGRLYHRHCFRCRRCSSTLLPGAYKNGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
VRSGTRPGSFPQPKQQHQQQLEE----DA------KDPPGGS------------------
-PSSSAP---------------AGAEADG---PKTSPD----SRPQ---IPTKPRVSGKP
QELA---------SPPAGRPTPAPRKASESTAPAP----PTPRPRSSLQQENPVEQAS--
SSSLMNG---------RLHEP---------------------------------------
-------------------------PIPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEDEE-NAEEEAPAA--------------
---------------------------------------------PDLATSPALA-HPES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESCS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PAGLSANSSLASSEELVQPR------VEQMPQ---ASP-GLAPR
TRGSP-GP---QLAKPC---SAATPTPLLLVGE--SSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGM--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NESREDDMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
VLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMRVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

ASPGQ-AGV--------------------
-----SPPRKG--LAPSSPASEAAASVEPG--DRAQDEERSSGSLAEQ--GAHRAPSSI

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGKLYHRHCFRCHRCSSTLLPGSYQDGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
GRSGARPGPPPQP---KQQQLA----GE-----A---KD-----------------VEAV
GPSPNAAA---G-------A--AEAEADM---PKASPE----ARPQ---IPTKPRVPGKP
--------QELAS-PPASRPTPAPRRASESTAPTPP----TPRPRSSLQHENLAEPGG--
SSVLVNG---------KLH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERTP--PPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPPPP--H
RQVENGGVAEVA---PRGLEVATLESKPYNPFEDEEE-EP-P-AATG-------------
---------------------------------------------------S-ALAHPES
TAKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
---VTLHA---SRLSHSEPPSATP-------SPALS--VESLASESSS------------
---------------------QPPSTELL---EPP----VVPKSCSEPAVHAPGTPGTS-
--A---------------SLSANSSLSSSGELAQPS------VDRTPQ---ASP-GLAPS
ARGSP-GP---PPAKPC---SGAAPTPLLLVEDK--SPAPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKP----SPTA-----------
---------------------------------------------SPTIK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEVDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFRLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFQKEAESEGKKKGKFKTMK
VLKLLGNKRDPKSKASVDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 151)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FSSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSAEPE--DVAQGEELSSGSLSEQ--ATGQTPSSR

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAE

ENSGT00760000118856_7_Linker_1_2 (293, 1283)

HCARLGPG
TGSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGN------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STSAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEEDEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVGLPTNSSLASSGELVEPR------VEQTPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAVS--------------------
-----P-PTSAKDPATPS-PTSASPAVQPG--EEAQDDELSSDRLAEQ--GRQQPPSSV

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRYCSSTLLPGSYSSGLEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCARLGPG
GGAGTRPLSQRRQQQVAE---------A-----A---KD-----------------GEDS
DPSPSVAG---V------------AEADG---LQASSE----VQPQ---ILNKPPLPSKP
--------QEVAS-PPVGRPTPAPRKASENSALTPP----TPRPRSSLQQDGLVDQGV--
SSGLVNG---------ELK--LP-------------------------------------
-------------------------SRQKADP----------------------------
---------LPWPPCRMP--APRKDPPWITLVQTEP-KKKPAPLPP-S-----SSPGPPS
RQVENGGLEERTQKSP----VAEPEPKPYNPFEEEE---ES-APAVP-------------
------------------------------------------------GPA--P-APPES
TPKALHPWYGITPTSS--------------------P-KTKKRPAPRAPSSCPPLQCFCC
SVATVLHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPTVHMPGTLGTSG
NSV---------------TPLADSSLSPSGELGQPS------GEQTPQ---T-------R
TRGNP-ST---QTTKPC---SGATPTPFLLAGDG--SPAPSPG-SSSPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQHIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDNMLVDWFKLI
HEKHLLVRRESELIYVVKQQNLE---QRQADVEFELRCLLNK--PEKDWTEEDRAREKVL
LQEFMTLVDQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQREAESEGKKKGRLKTMK
MLKLLGNKRDTKSKAPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYGGV
DIRDLSGSFRDGLAFCAILHR------HRPDLLKNAAP---VNLLPERPAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPGQA-AI--------------------
-----SPPRND--SKPPSSPSAAPTVSEPG--DNAQGKELSSGSLLEQ--GAPQPPSSM

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRFLAEGRLYHRHCFRCRQCSSTLLPGSYICGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCPRLGPG
GRLAGRPLSQ-----RKPQQVA----GE-----A---KD-----------------GEGG
DPSPSVAS---G------------AEAER---SQAGPE----ARPQ---IPSKPVVPGKP
--------QELAG-PAGGRPTPAPRKASESSAVTPP----TPRPRSSLQQDGSLEQGT--
GSGLVNG---------RLQ--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERKP--APRKEPPWITLVQAEP-KKKPAPLPP-GSSSGL--PSQAS
KQVENGGVDEGTRQSP----AAGSEPKPYNPFEDDEEEEESS-PAVPSP-----------
------------------------------------------------APV-----PSES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----AVHA---SRLSHSEPPSATP-------SPALS--VESLSSESCS------------
---------------------QAAGGELL---EPP----AVPKSSSEPAVHAPGTPGNS-
--A---------------SPSANSSLSSSGELVQPG------GERVPQ---A-------R
TRGSP-GA---LATRPC---TGATPTPLLVAPGR--SPAPAPGGGSSPQLQVKSSCKENP
FN------------------------------------RKP----SPAA-----------
---------------------------------------------SPTAK----------
------KA----TKG-------AKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDSLEHRGVVLEEKLRGGT--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGHEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQREAEPEGKKKGTFKTMK
VLRLLGNKRDTKSKSPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAAS--------------------
-----P-PKPGKDPAPPS-PTSTSPAVQPG--EEAQGDDLSPDSLSEQ--GKQQPPSSA

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
TACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
SRSGTRLLSQQRQQPAA---------TE-----A---KD-----------------AEDN
DPSLS--V----------------AEPDR---LQASSE----VQFH---TPTKPPLPSKP
--------QELAS-PPVGRPTPAPRKASESSALTPP----TPRPRSSLQQDGTVEQSV--
SSGLVNG---------RLQ--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERMA--APRKDPPWITLVQTEP-KKKPAPQPP-SSGPGP--LSQAY
RQMEDGGLEEQTQKSS----GTEPEPKPYNPFEEEEEEEGEPAPAVPSPSPAPAVPSPSL
APAVPSPSPAPPVPSPSLAPPVPSPSPAPPVPSPSPAPPVPSPSLAPPVPSPVP-APSEA
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LAIHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPAVHVPGTPGTSG
NSV---------------TPSANSSLSSSGELGQPS------GEQMLQ---A-------R
TKGSA-GT---HSTKPF---SGATPTPFLLAGDR--NPAPPVG-SASPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDNIERQLDALEHSGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEFELRCLLNK--PEKDWTDEDRAREKVL
MQELMTLIEQRDAIVNCLDEDR-QREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTIK
VLKFLGNKREAKSKAPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLSWCRRQ-------------CEGYGGV
EIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSPGQAGVSPSRKEL--T--------A-S
S-----------------PPLVAPSPAEPG--DETQSEELSSGSLSEQ--GAQRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 291)

C
AACQQHVHLVQRYLAEGRLYHRHCFRCRQCSGTLLPGAYKSGPEAGTFVC

ENSGT00760000118856_7_Linker_1_2 (291, 1290)

AERCTRLGPG
GQAGARPGPPSQPK---PQQLAE----EA------RDGEEGG------------------
-PSSSVA---------------A-----G---RKAVPE----ARPH---VPTKPPLPGKP
QELS---------SPVSGRPTPAPRKASDSMAPTP----PTPRPRSSLQQDSTAEQGG--
SGGLVNG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERT--PPARKDPPWITLVQAEP-KKKPAPLPP-GS-PRPPSRG--S
RQEENGTV-EEVTPR-GPAAGS--EPRTYNPFEDEE-EVEEPSPAA--------------
---------------------------------------------PSPAPSPAQAP-SEC
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLASESCS------------
---------------------QMAAGELL---EPP----AVPKSSSEPAVHAP------G
T------------PGNSASLSAHSSLSSSGELVQPS------VEQTPQ---ART-R----
--GS-PGP---QPAKPC---SGAAATP-LLVGD--RSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPTA-----------
-------------------------------------------------K----------
------KA----TKG-------PKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDAIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEGREDAMLVDWFKLI
HEKHLLVRRESELIYIFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDKSREKVL
LQELMTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFQKEAESEGKKKGKFKTIK
VLKMLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LPSESSS------------
---------------------QIASGKLL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------SASLSANSSLSSSGEVVQPS------VVQTPQ---ASP-GLAPK
TRGSP-GP---QPAKPC---SGATSTPLLLVGD--KCPASPP-ESSSPQLQLKSSCKENP
FN------------------------------------RKPSPAASPTT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEVDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGGEDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRSREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQKEAESESKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

------------------------GP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSAEPE--DVAQGEELSSGSLSEQ--ATGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGS------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEEDEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQTPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

--------------------------M

PF00307 // ENSGT00760000118856_7_Domain_0 (28, 152)

SASRNLQQWCSRQ-------------CEGYPGI
LIYDLSSSFRDGLAFCALIHR------HRPDLIDFDSLSKENVFENNRLAFEVAERELGI
PALLDPEDMVSMKVPDRLSIMTYLSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

RNSSPGEHSARV-G---------------
------------------KPQLKETSESPS--KEPSGGSLPQGSPNAQTSLIRSSISST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 299)

C
ALCQQHVHLVQRYLVEGKLYHRQCFRCKECSSTLVPGAYRPGTDAGTLVCTHHCHRPPTS
SPESEEDGT---------------------------------------------------
---------------------------------KQ-------KAVQ---TPPKPCVPEKP
ASSNKPPTELHPDPFPNMRPVPAPRRTSDVA--------PQPLPRSRAAAES----SPVR
PTSLINGEQ-------QSPAP---------------------------------------
-------------------------PIPKP--------------RS--------------
---------RQRSSEREDEEKQKKNPPWLSLVPATEPKRRAAPPPP-PLAQKPELGDEKS
QKSL-----N----D-TEKQSLSSKPTAYNPFEDEDEEEEAET-----------------
-----------------------------------------------------------S
SLKPGHPWYGITPTSS--------------------P-KSRKRLAPKAPNASPL------
----AHHSNLVSRLSHSEPPSGSP-------SPALS--TESLPTDAST------------
--------------------------KGQ---DPE----SVPKSSSEPTIHSPNKPEPSD
RDTT------TYLSTGVPSTSTNTSLSSSSELANTS------EAQVPT---ISI-PSTVA
SDSTPPE------K-----------KPLAKVSDRAGLPH---MTLLRSALSFQQICKQNP
FN------------------------------------RKSSPATSPIN-----------
-------------------------------------------------K----------
------RN----QKG-------PKPS-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADDYIPEDEIQMEMETIELRLDELERRGVELEHRLRKLE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NESDEDSLLVDWFKLI
QEKHTLVRRESELVYTTKQQSLE---QRQADVEYELRCLLNK--PEKDWLEEDKEREQVL
MQELVTLIEQRNAIVKCLDEDR-QREKEEDKIIEAMILKKDFHT--DPQKKKKGKFKPIK
VLKLLSPKQEPKVKSPKDKN-------------

------------------------------------------------------------
---------------------------------DF

PF00307 // ENSGT00760000118856_7_Domain_0 (96, 152)

NSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

ASPGQVLPSGGFHVSKPSSLSTKLFSGGP
AF-RGPVRREGKAQALSSPPLEAPTPTEPGER-AQEGRQRRQMSLSEQ--GAQRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 298)

C
AACQQHVHLVQRYLAEGKLYHRHCFRCRQCSSTLLPGAYRSGPEEGTFVCAEHCARLGPV
QPKQ--------------QQLA----EE--------VKD-----------------VDGG
GVGASAPA---------------GAEVDV---PKASPE----ARPQ---IPTKPWLPSKP
--------QELGS-SPAGHPTPAPRKAPESPALTPP----TPRPRSSLQHENSAEQGG--
SSGLDTS-----------------------------------------------------
------------------------------------------------------------
-------------------------------PQAEP-KKKPAPLPP-SSSPGPP--SRDS
RQVENGGAEEAAQQS---QVTAGPEPKPYNPFEEEEEDEPRAAPSL--------------
------------------------------------------------AAGPALAPSVES
APKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPLEPTSWK
LVVV------------GQPPGAVPPSTYHALSPMLFVSMVSITHMRIKAAQGGAWPGPAT
VGAAGSPPLLLVRGRGQASLDSVCPPLPLAASPPPLGFALGQIRQGRPAVHAPGTPGTS-
--A---------------SLSADSSLSSSGELVQPS------ADQIPQ---ASP-GLAPG
TRGSP-SP---QPAKPC---SGAAPTPHLLVGDK--SPVPSPG-SSSPQLQVKPSEGPRL
VRPWVEGGRTG----RVG------WLSS---RSDDLMEGKSGERGEPLVSEHRRLHSTSL
LSLPGSLSYIVISFLEWQRRRKGCHESAGARGMEGLGPSPQWPLPTPGSRTWPRWGAGQS
PGPGSGEASAGQRNG-------KAPG-SRQ-----------------------VGGVGCP
SGDRGIV----GQVQ----ADQYIPEEDIYGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELMTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRRKG-------------------
---------------------------------

------------------------------------------------------------
---------------------------------DF

PF00307 // ENSGT00760000118856_7_Domain_0 (96, 143)

NSLSKDNVFENNRLAFEVAEKELGI
PALLDPRDMVSMRVPELLNILTYTPIYR--IPSDGQXGVSPPRKDL--A--------P-S
S-----------------PPTVASPPMEPR--DKAQXXXXXXXXXXXX--XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX---XXX------XXXXXXX------------------
-XXXXXX---------------XXXXXXX---XXXXXX----XXXX---XXXXXXXXXXX
XXXX---------XXXXXX-X--XXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXX
XXXXXXX---------XXXXX---------------------------------------
-------------------------XXXXX--------------XX--------------
---------XXXXXXXT--PAPRKDPPWITLVQAEP-KKKLAPLPP-SSSPGPPSQD--S
RTVENGGV-EESAQQ-SPVA--GPEPKPYNPFEEEEGEEEES-PAA--------------
---------------------------------------------PSLATSPALA-HSEA
TSKTLHPWYGITPTSS--------------------P-KTKKRPAPRAPSTSPL------
----XXXX---XXXXXXXXXXXXX-------XXXXX--XXXXXXXXXX------------
---------------------XXXXXXXX---XXX----XXXXXXXX-XXXXXXX----X
X------------XXXXXXXXXXXXXXXXXXXXXXX------XXXXXX---XXX-XXX-X
--XX--XX---XXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSCKEDP
FN------------------------------------RKPSPAASPTT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDIHGEMDAIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------TEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQEIVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQKEAEPEGKKKGKFKTMK
VLKLLGNKRDAKSKSPGDKS-------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------GV--------------------
-----SPARKG--LASSSPPSEASPPVEPG--YRAQGEELSSSCLSEQ--GAHRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 299)

C
AACQQHVHLVQRYLAEGKLYHRHCFRCRQCSNTLLRGAYRSGPNVGTFVCAEPCARLASR
RWLGAKPGLPPQPKSKSKKQTA----EA-----A---KD-----------------VNGG
GPSPNAAA---G------------AEVDV---PKASPE----ARPQ---IPAKPQVPDKP
--------PELAS-PPASCPTPAPRKVSESTALTPP----TPRPRSSLQPENSMEQGG--
SSGLVNG---------RLH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPLPP-SGSPGP--PRQHS
GRAENGGVEEGT---PRSPAVPGPEPKPYNPFEEEE--EE-P-PAAPSL-----------
------------------------------------------------ATGPAQ-AHLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
---XXXXX---XXXXXXXX-XXXX-------XXXXX--XESLSS-EIS------------
---------------------QTPSGELL---EPP----VVPKSSSEPVVHAPGTPGTS-
--A---------------SLSANSSLSSSGELVQPS------MDQTPQ---ANP-GLAPS
TRGSP-GS---QPAKPC---SGAAPTPLLLVGEK--SLVPSSG-TSSPQLQVK-SCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPATK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEDDIHREVDTIERQLDALEHRGVLLEEKLRGGM--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NESREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQEIVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQKEAELEGRRKGKFKTMK
VLKLLGNKRDTKSKSPGDRS-------------

------------------------------------------------------------
---------------------------------

PF00307 // ENSGT00760000118856_7_Domain_0 (94, 152)

DFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMRVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSLGQAGVSPPRKGL--P--------P-A
S-----------------PPSEAATPVEPG--DKAQGEELSSDSLSEQ--GTHQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 298)

C
AACQQHVHLVQRYLAEGKLYHRHCFRCRHCSSTLLPGAYRSGPEEGTFVCAERCARLGPG
GRLGTRPGSLSQSKTQHQPQLAE----GA------KDVEGGC------------------
-SGPRVA---------------AVADADE---PKAGPE----ARAH---IPTKPRVPSKP
QELA---------SPPPSRPTPAPRKASESTALTP----PTPRPRSSLQHENMVEQGG--
SGGLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERP--PAPRKDPPWITLVQAEP-KKKPAPPPP-SSSPEPPGRR---
-RGEN-GNMEEVAPQ-SPVA--ALEPKPYNPFEEEEEESLAA------------------
---------------------------------------------SSLATGPSLA-HLES
TAKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----VLHT---SRLSHSEPPSSTP-------SPALS--VESLSSESSS------------
---------------------QTTSQELL---EPP----PVPKSSSEPVVHAPGP---PG
T---------------SAARSADSSLSSLGELGQPN------ADQMPQ---ASP-GLTTN
TRVSL-DP---QAAKPC---SGATPTPLLLVGDGSPAPS---AGASSPQLQVKSSCKENP
FN------------------------------------RKASPTASPAT-----------
-------------------------------------------------R----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDIHGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NESREDDMLVDWFKLI
HEKHLLVRRESELIYVSSSSK--NLEQRQADVEYELRCLSQQAGTEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQKEAETEGKKKGKFKTMK
MLKLLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
---------------------------------DFDSLS

PF00307 // ENSGT00760000118856_7_Domain_0 (100, 152)

KDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSAEPE--DVAQGEELSSGSLSEQ--ATGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------RDVPGGS------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
GSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEE--EEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QIAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVGLSTNSSLASSGELVEPR------VEQTPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1606)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR------------------QFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKCPRDKS-------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMSVPDCLSVMTYVSQYYNHFASPGQAGASSPKKGP--A--------P-S
S-----------------PPSEAPTPVQPE--DGAQDAELSPGSLSEQ--GPRRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 290)

C
AACRQHVHLVQRFLAEGKLYHRHCFRCRQCSSTLLPGAYRSGPEEGTFV

ENSGT00760000118856_7_Linker_1_2 (290, 1283)

CAEPCTRLGAG
GPSGARPQRPPQPRQQPPQQLAG---EDA------NAVEGGG------------------
-PGPGAA---------------A------------GAE----ARPQ---VPTKPRLPSRP
QELG---------SPPPGRPRPAPRKVSEGSAPTA----PTPRPRSSLQQENLAEQG---
SGGLVNG---------RLHET---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPEPPGWR--V
-----NGEVGEGAQQ-SPAA--RPEPKPSNPFEEDGEEEPPAA-----------------
---------------------------------------------PSPATSPAPA-HPEP
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPNASPL------
----ALHA---SRLSHSEPSSSTP-------SPALS--VESLSSESSS------------
---------------------QTTSGDLL---EPP----AVPKSSSEPAVHAPGT-----
-------------PSTTASLSTNSSLSSSGELGQPS------VDRTPQ---ASP-GPATS
AGGSP-GP---QPAKPC---SGAAPTPLSLVGD--RSPAPSP-GTSSPQLQVKSSCKENP
FN------------------------------------RKASPAASPAT-----------
-------------------------------------------------K----------
------KA----AKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEMDTIERQLDALEHRGVLLEEKLRGGM--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------HEGREDDMLVDWFRLI
HEKHLLVRRESELIYTFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDQGREKVL
MKELVMLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKVYLGPASAFP-------ECS
HICLSPD----PSQNPGRGVWPHPVDEETRGSK

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHFSSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSEEPE--DVAQGEELSSGSLSEQ--ATGQTPSSTC
AACQQHVHLVQRYLADGRLYHRHCVGGAP--APLLPG----------LMRMEHCARLGRD
TVRGPGLG-LSHSKAAAPAALAE----DA------KDVPGGS------------------
-PTSSAP---------------AGAEADD---QG-SPE----ARPR---SLPNPG-SWQP
QELA---------STLQAAPPPAPGGLR-EHRPAP----PTPGPLQSAAGEPGGAGWQ--
QRASWNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWIMLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEEEDEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVSLSTNSSLASSGELVEPR------VEQTPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAIL--HR----HRPDLIDFKSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TGPGQAAVSSPGKDP--T--------S-P
S-----------------PTSTSP-AAHPG--AEVQGEELSSDSLSEQ--GAQQPPSSV

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLLPGSYRSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRPGPG
GRLGTRPLSQ-------QQQQVT----EA------KDEEEGD------------------
-LSRSTA---------------ATAEADG---PQASPE----AQLQ---ILTKPPLPTKP
QELA---------SPPVGRPTPAPRRASESSVLTP----PTPRPRSSLQQDSLVEQGS--
GSGLVNG---------RLQEP---------------------------------------
-------------------------PIPKP--------------RG--------------
---------TPKLSERT--TAPKKDPPWITLVQAEP-KKKPAPLPP-SS-PALSSRA--S
RQVENGGM-EEGLQQ-NPVA--VREPKPYNPFEEEEEEEESAPPVPSPAPA---------
-----------------------------------------ASSLAPAAPSPASV-SLES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPSASPL------
----VLHA---SRLSHSEPPSATP-------SPALS--VESLSSESCS------------
---------------------QTANQGLL---EPP----AVPKSSSEPAVHAPGA---HG
T------------PGNSASPSANSSLSSSGELVQPG------GEQLPQ---ART------
-----RGS---PGTKPC---SGATPNPLLLAGD--RSPAPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPSASPTP-----------
-------------------------------------------------R----------
------KA----TKG-------AKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRVREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQRETEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

------------------------------------------------------------
---------------------------------

PF00307 // ENSGT00760000118856_7_Domain_0 (94, 152)

DFDSLSKDNVYENNRLAFELAERELGI
PALLDPNDMVSMKVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

NNPNQARVPPPMKRP--AAAASPPL----
----LAHKKPVAAVESSSE----------------PQDDAPVEP-AELSQSQRTMLSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 337)

C
TACQQHVHLVQRYLAEGKLYHRQCFRCKECSSTLLPGSYKPGSEAGTFVCTQHRG-----
---------------------------------AEVGKDNDSV--EE-TVAET------Q
MPAEVPTNPEE------KDSTPSRAETAIP--CAGSGA----PISQ---IPPRPPLPSKP
LVPSQDKAGSLDGQHRQTRPTPAPRRSTD--ALSPPASHPVPRPRSTIQGEASDS-----
GPGMVNG---------RVPEPSP-------------------------------------
-------------------------PVPKPRG----------------------------
---------RPCSSDRAGGAARAKDPPWMALVQAEP-KKKPAPP-PPGSGQETPSRTLEE
EDGEEVGK----ARS-EESRSDATEPKSYNPFEEEGDEEEESTAAQK-------------
-------------------------------------------------STPE-QEQSET
AARPLHPWYGITPTSS--------------------P-KVKKRPAPRAPNASPL------
----AHHP--ISRLSHSEPSSSTP-------SPALS--LESINSESSA------------
---------------------KVLGD--T---DEA----SVPKSSSEPTVHTPTATKTSH
TDTPLTSVSSSESPAAPASLSTNSSFSSSSELASFS------AEVQNSTLHASR-SVSTG
SLKTSPSR---LPPKPP---AGASPTSMLLASEGGT---GSPKPSSSPKPQLKSSCKENP
FN------------------------------------RKPSPVASPSA-----------
-------------------------------------------------K----------
------KP----PKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----TDQYIPEEDIYGEMDAIEHQLDQLEHRGVILEEKLRSSE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NDSPEDSLLVDWFKLI
HEKHMLVRHESELIYIFKQQNLE---QRQADVEYELRCLLNKP-VEKDWTEEDRVREKVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFHKEAETETKKKGKFKPMK
VLKLLGNKHDSKSKSPKEKS-------------

------------------------------------------------------------
---------------------------------DFDSLSKDNVFENNRLAFKVDEKELGI
PALLDRNDMICMSVPDCLSIMTYVSQYYNHFASPGQ-AGV--------------------
-----SSPRKA--QAPSSPPSEASTPAEPG--DRAQGEELSLGSLSEQ--GTQRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYWAEGKLSHRHCFRCRQCSSTLLPGAYRSGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1283)

CARLGPG
GRSGTRPGPPLQP---KQQQLG----EE-----V---KD-----------------VDGG
GPGRTAPA---G------------AEAEG---SQASPE----ARPQ---ITTKPRLPNKP
--------QELGG-SPAGRPTPAPRRAPESPAPTPP----TPRPRSSLQHENLAEQGG--
SSGLVNG---------RLH--EP-------------------------------------
-------------------------PVPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPLPP-SSSPGP--PSRDS
RRVENGGTEEVG---QQSQGPAGLEPKPYNPFEEEEE-EE-P-PAAPSL-----------
------------------------------------------------ATGPALVPSVES
TPKSLHPWYGITPS-S--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTPSGELL---EPP----AVPKSSSEPTVHAPGTPGTS-
--A---------------SLSANSSLSSSGELVQPG------ADQIPQ---AGP-GLAPG
SRGSP-GP---QPPKPC---GGAAPTPLLLVGDK--SPAPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPTTK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRRKEFQKEAEPEGRKKGKFKTMK
VLKLLAHKRDTKSKPPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 151)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNH

ENSGT00760000118856_7_Linker_0_1 (151, 240)

FAGSGPA-GV--------------------
-----SSPRKG--LVLSSPPSEASTPADPG--DRAQGEECSSGSLSKQ--GSHRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACQQHVHLVQRYLADGKLYHRHCFRCRRCSSTLLPGAYRNGPEEGTFVCAE

ENSGT00760000118856_7_Linker_1_2 (293, 1283)

HCARLGPS
GRSGARPGTPPQP---KQQQLT----EE-----A---KE-----------------VEGG
SPSPKATA---G------------AEADV---PKASPE----GRPQ---VPTKPRVPGRP
--------QELAS-PPASRPTPAPRKASESTAPTPP----TPRPRSSLQQENLVEQGG--
GSGLVNG---------KLQ--EP-------------------------------------
-------------------------PIPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPP-PGQEG
RQVENGGVDKAA---P-----RGPEPKPYNPFEEEE--EE-P-PAAPSP-----------
------------------------------------------------APGPAPTP-PES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSTSPL------
----TLHA---SRLSRSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QAPSEELL---EPP----VVPKSSSEPAVHAPGTPGTS-
--A---------------SLSANSSLSSSGELVQPS------MDRTPQ---ASP-GLAPN
SRGSP-GP---PPAKPC---SGTAPTPLVLVGDK--SPAPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKP----SPTA-----------
---------------------------------------------SPSVK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----SDQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIHGEIDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQKETEPEGKKKGKFKTMK
VLKLLGNKRDTKSKCPGDRS-------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMSVPDCLSIMTYVSQYYHHFTGPSQAGISPPRKDL--A--------S-S
T-----------------PPSAVPIPAEPG--DEAQNEKLSSGSLSER--GAQRAPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACQKHVHLVQRYLAEGKLYHRHCFRCQQCSSTLLPGAYKSGPEEGTFVCT

ENSGT00760000118856_7_Linker_1_2 (292, 1289)

ERCTRLGPG
GQAGARPGPPSQPK---SQQLEE----EA------RDGEGGG------------------
-PSPGVA---------------A-----A---PKAIPE----ARPH---IPTKPPLPGKP
QELA---------SFPSSRPTPAPRKTSDSVASTP----PTPRPRSSLQQDSSAEQGG--
SGGLANG---------RLQEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKLSERM--PPPRKEPPWITLVQAEP-KKKPAPPPP-GS-PGPPSRA--S
RQVENGGV-EEMPQC-SLVAGTSREPKPYNPFENEE-EPEEPSQAA--------------
---------------------------------------------PSSAPSPAQAP-PEC
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRVPSVTPH------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLASESSS------------
---------------------QIGGGELL---EPP----AVPKSSSEPAVHDPGTSGTPG
T------------PGNSASLSAHSSLSSSGELVQPS------VEQTPP---AGI-K----
--DS-PGP---QPARPC---SGAIPTPFLLVGN--RSPAPSP-GSSSPQPQVKSSCKENP
FN------------------------------------RKPSPAASPTA-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYVPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

ICGEMDAIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SEGCEDDMLVDWFKLI
HEKHLLVRRESELIYILKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDKSREKVL
MQELMTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKEFQKEAEPEGKKKGKFKTMK
MLKMLGNKRDTKSKSPGDKS-------------

-------------------------------MALLFTEEH-------------SDGTE--
----KEPGRRKTLGQLTATNL------Q

PF00307 // ENSGT00760000118856_7_Domain_0 (89, 152)

RPEGKDFQSLSKENVFENNRLAFEVAEKELGI
PALLDPNDMVSMNVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAVA--------------------
-----P-PTPAKDPAPPS-PTSASPAVKPG--EDTQGDDLSSDSLSEQ--GKQQPPSSV

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLLPGSYISGLEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

ERCTRLGPG
GRSGTRPLPQQKQQQVAE---------E-----A---KD-----------------GEES
DPSPSVAE---V------------AKADG---LQPSSE----VQPQ---TLNKPPLPSKP
--------QEVAS-PPVGRPTPAPRKASENSALTPP----TPRPRSSLQQDGLVEQGV--
STGLVNG---------RLQ--EP-------------------------------------
-------------------------PIPRPRG----------------------------
---------TPKLSERMP--APRKDPPWITLVQTEP-KKKPAPLPP-S-----NSPGPLS
RHVENGGLEERTQKSP----VSEPDPKPYNPFEEEEEEEES-APAVP-------------
------------------------------------------------GPVPAP-APPES
TPKPLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASP-------
---LVLHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------HTANAEPL---EPP----AVPKSSSDPAVHMPGTPGTSG
NSV---------------TPSANSSLSPSGEQGQPS------GEQMPQ---A-------R
TRGSP-ST---QATKPC---SGATPTPFLLAGDR--SPAPSLG-SSSPQLQIKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPTVR----------
------KA----TKG-------AKPM-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

YGEMDTIERQLDALEHRGVLLEEKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDNMLVDWFKLI
HEKHLLVRRESELIYVVKQQNLE---QRQADVEFELRCLLNK--PEKDWTEEDRAREKVL
LQEFMTLIDQRNAIVNCLDEDR-QREEEEDKMLEAMIRKKEFQREAESEGKKKGKFKTMK
MLKLLGNKRDTKSKVPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTSAEPE--DVAQGEELSSGSLSEQ--ATGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
TRSGTRPGPFSQPKQQHQQQLAE----DA------KDVPGGS------------------
-PSSSAP---------------AGAEADG---PKASPE----ARPQ---IPTKPRVPGKP
QELA---------STPAGRPTPAPRKASESIAPAP----PTPRPRSSLQQENLVEQAG--
SSSLVNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGT--PAPRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPAA--SLEPKPYNPFEEEE-DEEEEAPAA--------------
---------------------------------------------PSLATSPALG-HLES
TLKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QTAGGELL---EPP----AVPKSSSEPAVHAPGT---PG
N---------------PVGLSTNSSLASSGELVEPR------VEQTPQ---ASP-GLAPR
TRGSP-GP---QPAKPC---SGATPTPLLLVGD--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPVT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGL--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRAREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
MLKLLGNKRDAKSKSPRDKS-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------M---ICP-GLAPD
TRGGP-GP---QPAKPC---GGAAPTPLLLVGDK--SPVPSPG-TSSPQLQVKSSCKENP
FN------------------------------------RKA----SPTA-----------
---------------------------------------------SPTTK----------
------KA----TKG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQSLE---QRQADVEFELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIRRKEFQREAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPGDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
EIRDLSSSFRDGLAFCAIL--HR----HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSIPDCLSIMTYVSQYYHHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

SSPGQAGVSPPRKGL--A--------P-C
S-----------------PPSVAPTPAEPE--DVAEGEELSSGSLSEQ--GTGQTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACHQHVHLVQRHLAEGRLYHRHCFRCRRCSSTLLPGAYKNGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPG
VRSGTRPGSFPQPKQQHQQQLTE----DA------KDAPGGG------------------
-PSSSAP---------------AGAEADG---PKASPD----SQPQ---IPTRPRVPGKP
QELA---------SPPAGRPTPAPRKTSESTALAP----PTPRPRSSLQQENPVEQAS--
SSSLMNG---------RLHEP---------------------------------------
-------------------------PVPKP--------------RG--------------
---------TPKPSEGI--PAPRKDPPWITLVQAEP-KKKLAPLPP-SSSPGPPSQD--S
RQVENGGT-EEVAQP-SPVA--SLEPKPYNPFEDEEN-EEEEAPAA--------------
---------------------------------------------PDLAASPALA-HPET
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPCAPSASPL------
----ALHA---SRLSHSEPPSATP-------SPALS--VESLSSESSG------------
---------------------QTAGGELL---EPL----AVPKSSSEPAVHAPGT---PA
N---------------PA----NSSLASSEELVQPR------VEQMSQ---ASP-GLAPR
TRGSP-GP---QLAKPC---SGATPTPLLLVGE--RSPVPSP-GSSSPQLQVKSSCKENP
FN------------------------------------RKPSPAASPAT-----------
-------------------------------------------------K----------
------KA----TKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEMDTIERRLDALEHRGVLLEEKLRGGM--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGHEDDMLVDWFKLI
HEKHLLVRRESELIYIPRQNLSSLQPLPLADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIINCLDEDR-QREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMK
VLKLLGNKRDTKSKSPRDKS-------------

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLLDFDSLSKDNVFENNRLAFEVAEKELGI
PALLDPNDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

AGSGPA-GV--------------------
-----SSPRKG--LALSSPPSEASTPADPG--DRAQGEECSPGSLSKQ--GSHRTPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 294)

C
AACQQHVHLVQRYLADGKLYHRHCFRCRRCSSTLLPGAYRNGPEEGTFVCAEH

ENSGT00760000118856_7_Linker_1_2 (294, 1289)

CARLGPS
GRSGARPGTPLQP---KQQQLT----EE-----T---KE-----------------VEGG
SPSPKATA---G------------AEVDV---PKASPE----GRPQ---VPTKPRVPGRP
--------QELAS-PPASRPTPAPRKASESTAPTPP----TPRPRSSLQQENLVEQGG--
GSGLVNG---------KLQ--EP-------------------------------------
-------------------------PIPKPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQAEP-KKKPAPLPP-SSSPGPP-PGQEG
RQVENGGVDKAA---P-----QGPEPKPYNPFEEEE--EE-P-PAAPSP-----------
------------------------------------------------APGPASTP-PES
TPKSLHPWYGITPTSS--------------------P-KTKKRPAPRAPSTSPL------
----ALHA---SRLSRSEPPSATP-------SPALS--VESLSSESSS------------
---------------------QPPGEELL---EPP----VVPKSSSEPAVHAPGTPGTS-
--A---------------SLSANSSLSSSGELVQAS------VDRMPQ---ASP-GLAPN
ARGSP-GP---PPAKPC---GDTAPSPLVLVGDK--SPVPSPG-ASSPQLQVKSSCKENP
FN------------------------------------RKP----SPTA-----------
---------------------------------------------SPSVK----------
------KA----TRG-------SKPA-RPP-----------------------APGHG--
--FPLIK----RKVQ----SDQYIPEED

PF12130 // ENSGT00760000118856_7_Domain_2 (1289, 1592)

IHGEIDTIERQLDALEHRGVLLEEKLRGGV--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGREDDMLVDWFKLI
HEKHLLVRRESELIYVFKQQNLE---QRQADVEYELRCLLNK--PEKDWTEEDRGREKVL
MQELVTLIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKKKEFQKEAESESKKKGKFKTMK
VLKLLGNKRDTKSKCPGDRS-------------

------------------------------------------------------------
------------------------------------------------------------
--------MVSMKVPDCLSIMTYVSQYYNHFNNPSQASVPPPMKRP--AAASSPPL----
----LSRKTPVAAVESPSAPQ----------------EDV------PSERRQRGALSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 293)

C
AACQQHVHLVQRYLAEGRLYHRQCFRCKECSSTLLPGSYKPGAEAGTFVCTQ

ENSGT00760000118856_7_Linker_1_2 (293, 1283)

HRGKLAVS
GKAERRHSPERQSAELRTETGAGSMEENALQAAAEVGKDDGDS--QE-SVAETPALTESP
APAESPAGPAE------KDSTASKAETPTPPAHAGSGA----PASQ---TPPRPPIPSKP
AGLAQDKASTLDGRLRDPRPTPAPRKATDVSALSAPPSHPVPRPRSTLQGEGSEC-----
GPAMVNG---------RVPEPSP-------------------------------------
-------------------------PVPKPRG----------------------------
---------RPCSSDRGGAAARAKDPPWMALVQAEP-KKKPAPPPPPGNNHETPSRTSEE
EDGEELGK----ARS-EESRSDTTEPKPYNPFEEEDEEEVESADTQK-------------
-------------------------------------------------STPE-QEQSET
AAKPLHPWYGITPTSS--------------------P-KAKKRPAPRAPNASPL------
----AHHP--ISRLSHSEPSSSTP-------SPALS--LESINSESSA------------
---------------------KVLGD--T---DEA----SVPKSSSEPTVHLPTAAKTSS
ADAPLASVSSSESPAVPASLSTNSSFSSSSELASLS------GEIQPSTLHASR-SISTS
NLKTSPSR---LPPKPP---AGASPTPILLASDGGA---GSPKTSSSPKPQLKSSCKENP
FN------------------------------------RKPSPAASPSA-----------
-------------------------------------------------K----------
------KP----PKG-------SKPV-RPP-----------------------APGHG--
--FPLIK----RKVQ----TDQ

PF12130 // ENSGT00760000118856_7_Domain_2 (1283, 1594)

YIPEEDIYGEMDAIEHQLDELEHRGVALEEKLRSAE--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NDNPEDSLLVDWFKLI
HEKHMLVRHESELIYIFKQQNLE---QRQSDVEYELRCLLNKP--EKDWTDEDRGREKVL
MQELVTIIEQRNAIVNCLDEDR-QREEEEDKMLEAMIKRKALTGMTSTMWRRMRAWRTWR
TRRRRDRR--TWRFCPRESGSRQTRSGSPPPT-

----------------------MAGP

PF00307 // ENSGT00760000118856_7_Domain_0 (27, 152)

RG---ALLAWCRRQ-------------CEGYRGV
DIRDLSSSFRDGLAFCAILHR------HRPDLIDFQSLSKENVFENNRLAFDVAEKELGI
PALLDPSDMVSMSVPDCLSIMTYVSQYYNHF

ENSGT00760000118856_7_Linker_0_1 (152, 240)

TSSGQAAVS--------------------
-----PHSTPGKDPASPS-PTSASPAVPPG--EEAQGDDLSSDSLSEQ--GRQRPPSST

PF00412 // ENSGT00760000118856_7_Domain_1 (240, 292)

C
AACGQRVHLVQRYLAEGKLYHRHCFRCRQCSSTLLPGSYSSGPEEGTFVCA

ENSGT00760000118856_7_Linker_1_2 (292, 1290)

KRCARLGPG
GRSGARPFSQREQQQVAE---------E-----A---KD-----------------GEES
DLSPSVAA---V-------A--AAAEGDG---LQASSE----VPPQ---TQSKPPLPSKP
--------QELAS-PPVGRPTPAPRKASESSALTPP----TPRPRSSLQQDGLVEPSV--
STGLVNG---------RLP--EP-------------------------------------
-------------------------PVPRPRG----------------------------
---------TPKLSERTP--APRKDPPWITLVQTEP-KKKPAPLPP-SGSSSSSSPGPPG
RQVENGGLEGRTQKSP----VAGPEPKPYNPFEEDEEGEE---PASA-------------
------------------------------------------------GPSPAP-APPES
TPKSLHPWYGITSTSS--------------------P-KTKKRPAPRAPSASP-------
---LVLHA---ARLSHSEPPSATP-------SPALS--VESLSSESSS------------
---------------------PAAKAGPS---EAP----AVPKSSSDPAVHVPGAPGTSG
NSA---------------APSAHSSLSSSGELGQPA------GEQVPQ---A-------R
TRGSP-GT---QATKPC---SGATPTPFRLAGDR--SPAPSPG-SSSPQLQVKSSCKENP
FN------------------------------------RKP----SPSA-----------
---------------------------------------------SPAVR----------
------KA----TKG-------AKPM-RPP-----------------------APGHG--
--FPLIK----RKVQ----ADQYIPLEDI

PF12130 // ENSGT00760000118856_7_Domain_2 (1290, 1592)

NTMMDNIERQLDALEYRGILLEDKLRGGA--
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------NEGSEDDILVDWFKLI
HEKHLLLRQESELNYVVRQQDLE---QRQADVEYEVRCLLNK--PEKDWTKEDRDREDAL
MKEFMTLIEQRNAIVTCLDEDR-QRDEEEDKMVEAMIRNKEFQKEAESEGKKKGKFKTMK
MLKLLGNKRATKSKAPGDKS-------------