Query Results 

---MRVHPRPHSRLVA-------KLAGLEPKTPYPGFE----SSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PIPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGAPEPPPSPPKTT-SPEPQESPTLTSTEGQVVNKLL
----SGPKETPAAQ--SSTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQQA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGRSDT
SSRFSKEQQGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTCTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAS-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MAVAFEERLSQALQEL
QAVAEAGRAAVTQAVDAALATVEPVAQAAEELRAETAALSRRLDTLSRQVEVLSLRLGVP
LVPDLESELEPSELLLAAADPEALFQAAEDAGPPVAHPPAFSTRR-SSSGGPSRRSSLME
PDPAEP-ASVTVEAANGAEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEALMAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDGGSSSSSTTVQT------------------------------
-------K-------------------TFS-------------------------S-SSS
SSKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-SGGPGTPRTAAVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1362)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
K-----------------------------CVYTYIQEFYRCLVQKGLVKTKKS-

---MRVYPRPHSRLAA-------KLAGLEPETPYPGFE----FSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 991)

EIEAATLAGRLYSGRPNSGSREDSK-GLA-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GINQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTPASP-----
------EPPLEPAE-AQCLTAEVPGSPEPPPSPPKTT-SPEPQESSTLPSTEGQVVNKLL
----SGPKETPAAQ--STTRGPSDTKRA--DVAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQQGVAQPLAQLRSCPQEEGPRGRGLAA---RPLENRAGGPVA-----------
---RSEEPGA------LLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTRSTSLME
PEPAEP-LAAAVEAANGAEQT--QVNKAPE

PF12510 // ENSGT00760000118856_3_Domain_2 (991, 1036)

GRCPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
-------------------------LEVTADLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHSQQREAEQRAALARLAGQLESMNDVEE-LTTLLRSAAEYEE
RKLIRAAIRRVRAQEIEAATVAGRLCSGRLNKGVREDSE-GRA-ARRLERREVPEQEEQE
QPAEVLE--PTPTP-E-VSNQDVTTVTLLLRAPGGGSPSSP--ASPDSSPTPVSP-----
------EPPPEPAG-AQGSPAEAPSSPKPPASPPRTTASPEPRESSVPPSTERQVVNQLL
----RGLAEPPAAQ--DSPRGPSNTKRA--XXXXXXXXXXXXXXXXXX--------XXXX
XXXXXXXXXX------------XXXXXXXX--XXXXX----------XXXXXXXXXXXXX
XXXXX-------XX-----XXXXXXXXX--------------------------------
---XXXXXXXXXX------------------XXXXXX----XXXXX-XX-X-------XX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX---XXXXXXXX--X------------
---X-----X------XXXXX--XXXXXXXXXXXX-XXXXXXXXXXXX-XXXXXXXXXXX
--XXXXXXXXX--XXXXX-X-XXXXXXXXXXXXXXXXX-XXXXXXXXXXXX---------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------XXXXXXXXXXXXXXXX-XXXXXXXXXXXXME
PAPAEP-PSVAVEAANGAEQT--RVDKAAEGRTPLSAKELAAIEDEAVLDKMLDQTMDYE
ERKLIRAALRELRQRKRDQRDKEREQRLQEARARPGEGRGNTAT-ETTMRHSQQAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFIRRSENGSGS----T-MVQTKTFSSSS---S
SSKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGG-TGSPGTPRA-AVQRSTSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYAQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRMRGKNV

---MRVYPRPHSRLVA-------KLAGLEPKTFYPGFE----FSELVTGATGTGNLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELRASKMSDDTLAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLYSRHPNGGSREDSK-RQA-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSCSP--ASPYSSPTPASP-----
------EPPLEPAE-AQCPTAEVPGSPEPPTSPPKTT-GPEPQESPTPPSTEGQVTNKLL
----SGRKETPAAQ--SPPRGPSDTKRA--DLARPQPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPQAAL--------------------------------
---GPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQLRVAQPLAQLRSCPQEEGPRGRGLAA---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLTRL-GSVTHVTSFSHASP-G-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTSTARSTSLME
PEPAEP-PSVAVEAANGAEQT--QVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPVEGRGNTAT-ETTMRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFMRRSENGSGS----T-MVQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-ACSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

--------------------------------------------ELVSGAVGTEDLTGR

PF12510 // ENSGT00760000118856_3_Domain_0 (60, 109)

R
RTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 142)

ELEREEEALASK
RFRAERQD----NKENWLHSE

PF12510 // ENSGT00760000118856_3_Domain_1 (142, 195)

QREAEQRAALARLAGQLESMNDVEE-LTTLLRGAAEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 987)

EIEAATVAGRLCSGRPNSGTRDDGQ-GRAAAHRLERREVPERKEQE
QQAEVLE--PTPTP-PEVISQDVTSVTLLLRAPAGGTPSSA--ASPDSSPPTASP-----
------EPPLEPAG-PQCPAAEAPGSPEPPASPPRATASPEPQEPPASSGTERQVTNKLL
----PGPTEPPAAQ--GPARGPSDTKRA--DPAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------EPTPLATGPSPFQRA----------GSVRDRVRKFTSD
SPATA-------RL-----QDGPPQAAL--------------------------------
---GPQTPAKLLG------------------PSLIST----TPASS--SSGYSSRSPGGN
TSSXXXXXXGIARPLAQLQSCPREEGPQGRGLAA---RSLENRAGGPGA-----------
---CSEEPSA------PQPVAVGT-AAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHVSSPGTLTRL-GSVTHVTSLSHASP-G-NRGG
YSFKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSSGPARSSSLME
PEPAEP-PSVAVEAANGTEQT--RMD

PF12510 // ENSGT00760000118856_3_Domain_2 (987, 1036)

KAPEGRTPLSAKELMAIEDEAVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1244)

KRDQRDKEREQRLQEARARPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFMRRSENGGGS----T-MVQTKTFSS--S-S-
-SKKMGSIFDREDQSSPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGAPRA-AVQRSTSFGVPNANSIKQMLLDWCRAKTR

PF11971 // ENSGT00760000118856_3_Domain_3 (1244, 1343)

GYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYAQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 106)

MADEALAGLDEGALRKLVEVTADLAERRRIRSAIREL

ENSGT00760000118856_3_Linker_0_1 (106, 146)

QWQELERKEEALASK
RFGAEQQD----NKENWLHSQHREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAGQLESMNDVEE-LTTLLRSAGEYEE
RKLIQAAICRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATVAGRLCSGRPNGSSRVDSK-RQA-AHRLEPREVPEHKEEE
QQAEVSE--PTPTP-K-VTSQDVTMVTLLLRAPPGNTPSST--ASPDNSPTTASP-----
------EPPLEPSG-VLCAAAEAPGNPEPPSSTPRT---PNLPESLTQPIMEGQVANKLL
----PGSTEPLAAQ--SPTRGPSNKNRT--DLAGPQPRQRSLSVLSPR--------QPAQ
NQ--------------------ESTPLGSSPSPFHWA----------GSVWDRVRKFASD
SPMAA------------RVQDGPTRATL--------------------------------
---GSLTPTRLLG------------------PSFIST----TPASS--SRSSSSRGPSDT
SSKFNKEQRGITQPLAQLQSCPQEEGPRGRGLAA---RSLENRAGSPSA-----------
----------------PLPVA--VGTTEPGGSMKT-TFTIEIKDGRGQASPGRVLLPTGN
QRAELTLRLRTPPTLLSTSSGNKNTITHASSPGTLTRM-GSVTRVTTFSHASP-G-SRGG
CSLKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPTEP--------------------------
-------PSTALKATNGAEQT--QADKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
EWKRIRAALCELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1200)

KRDQRDKERDS-------WPEERRGNTCT-ETTTRHSQRTADGST
VSTITKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS---S
SSKKTGSIFDREDQASPRAESLAAPEKRQAEKKKELMKAQSLPKTSASQACKAMIEKLE

PF00307 // ENSGT00760000118856_3_Domain_3 (1200, 1364)

K
EGN-------------------------------------------------FSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM---------
-------------------DMIMGKKPDPKCVFTYVQSLYNHLRRHELHLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTSDLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQHREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAKQLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATVAGRLCSGRPNSSSREDSK-EQA-AHRLEQCE--------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------LAGPQPCQRSLSVLSPR--------QPTQ
NQ--------------------ESTPLGIGHSPFHRA----------GSVRDRVRKFASD
SPMAA-------RL-----HDGPTRATL--------------------------------
---GSPTPTRLLG------------------SSVIIS----TTPASS-SRSSSSRGPSNT
SSESSKEQRGTTQPLAQLQSCPQEEGPRGRGLAA---RSLENRAGEPVA-----------
---CSEEPSA------PLPVA--VSAAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTSN
QRAELTLGLRTPPTLLNTSSGNKSTITHVSSPGTLTRM-GGVTQVTTFSHASP-G-SRRG
CSTKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPVQP--------------------------
-------PFTAVEAANGAEKT--QVDKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKEREQRLQEARGRPGERRSNTST-EMTTTHSQRAADGSA
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-SGSPGGPRT-GVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1362)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
ETHADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

---MRVYPRPHSRLVA-------KLAGLEPETFYPGFE----FSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADDALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAEQQD----NKENWLHSQQQEA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLYSGRPNSGSREDSK-GRA-AHRLEQCEVPEQEEQE
QQAEVSK--STPTP-E-GTSQDVTTVTLLLQTHPGSTSRSP--ASPYSSPTPASP-----
------EPPLEPAE-AQCPTAEVPGSPEPPASPPKTT-SPEPQESPTPPSTEGQVANKLL
----SGHKETPAAQ--SPPRGPSDTKRA--DLARPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---GPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQHGVAQPLAQLRSCPQEEGPRGRSLAA---RPLENGSGGPVA-----------
---RSEEPGA------PLPVAVGT--AGPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLTRL-GSVTHVTSFSHASP-G-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTSTARSTSLME
PEPAEL-PSGVVEAANGAEQT--QVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1231)

KRDQRDKERERRLQEARARPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFMRRSENGSGS----T-MVQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-ACSPGGPRA-AVQRSTSFGVPNASSI

PF00307 // ENSGT00760000118856_3_Domain_3 (1231, 1364)

KQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADDALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSEQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATLAGRLCSGRPNS-SREDRE-ERV-ARRLDRREVPEQEEQE
QQTKVPE--STPAP-K-DTSQDVTTVTVLLRAPPEDTPSSP--ASPDSTPTVASP-----
------EPLLEPAG-VPCPAAEAPGSPEPPLSPPQA-PSPEPPVSPSPSSPERQPEDKLL
----PGSTEFPATQ--SPTRGPSSTKRA--DLAGPQSCQRSLPVLSPQ--------QPAQ
NQ--------------------VSSPLASGPSPFQRA----------GSVRDRVRKFTSD
SPMSA-------RL-----QDGPPRAAL--------------------------------
---TSLTPTRLLG------------------PSLIST----TSASSS--SSSSSQGPSNT
SSRFSK-ERGTAQPLAQLQSCPQAEGPEGRSLAA---RSLENRAGGPRT-----------
---CSEEPSA------PLPA----STAESGGSMKT-TFTIEIKDGRGQASTGRVLLPAGN
QRAELTLGLRTPSTLLSSSSRSKSTITHVSHPGPQARL-GSVTRVTTFSHASP-G-SRGG
YSIKTE------------------------------------------------------
------------------------------------------------------------
----------------------------PEPVEP--------------------------
-------PSTAVEVANGTKQT--RGDKAA

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSPEELLAIEDESVLDKMLDQATDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGQSQTNTTT-ETTTRRSQRAADGSA
ISTVTKTERLVHTSDGTRTARTTTVESSFVRRSENGGGS----T-TVQTKTYSSSS-SSS
SSKKMGSIFDREDQASARPGSLAALEKRQAEKKKELMKTQSLPKTSASQARKAMIEKLEK
EGT-AGSPGGPRT-PVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRHNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRMRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALTRLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATLAGRLCSRLPSSGPREDSR-RQA-AHTLDPGKVPEPEQQK
QQTEGREPTP----TPEDTSQDVTTVTLLLRAPPGSTPGSP--ASPDNSPTGASP-----
------EPRLEPPG-AQCPTAEAPVSSEPLPHPSEA-PSPEPPMSPVPPSSQGRVISKPL
----PGPTEPSDTL--DSARGSSNTKRA--DPAESKPCQRSLSVLSPR--------QPTP
NQ--------------------EPTPLAG-PSQFRRA----------GSVRDRVRKFTSD
SPVVA-------RL-----QDGPPRIAL--------------------------------
---TSQTPTRLPG------------------PSLIST----TPASSSS-SDSSSLSPSDT
SS--HKKQRELAHSLAQLQSCPQEEGPRGRGLAL---RSLENRAGGPKS-----------
---CSEEPST------PPPVA--IGTGEPGGSMKT-TFTIEIKDGRGQGSTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHISNPGTVTRL-GSVTRVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PSATVEAANGAEQA--RVDKGP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEDLMAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLREARARPGESRSNVAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTQTARTTTVESSFMRRSENGGSSSS-TTTTVQTKTFSSSS-SSS
SSKKMGSIFDREDQTSSRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGGPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQE----NKENWLHAQHQEA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALTRLAGQLESMNDVEE-LTTLLRSAGKYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATVAGRLCSGQSNSGSREHSK-GQA-AHRLEQCEVSEPK-EE
QQAEIPE--PTPTP-E-GTGQDVTTVTLLLRAPPGDTPGST--ASPDNSPTTASP-----
------EPPLEPAG-AQCGAAETPGSPEPPPSTPRT-PTPEPPESLAQPNTEGQVVSKLL
----PGPTELPAAQ--APTRGPSNKNRA--NLAGPQPCQRSLSVLSPR--------QPAQ
NQ--------------------ESTPLASGPSPFQRA----------GSVRDRVRKFASD
SPTAA-------RL-----QDGPTRAAL--------------------------------
---GSLTPTRLLG------------------PSLIST----TSASS-SS-SSSSLGPSDI
SSQFSKEQKGIARPLAQLQSCPQEEGPRGRGLAA---RSLENSAGGPMA-----------
---CSEEPSA------PLPVA--VGTPEPGASMKT-TFTIEIKDGRGQASTGRVLLPTSN
QRAELTLGLRTAPTLLTTSSGNKSTIAHVSSPGTLTRM-GSVTHVTTFSHGSP-G-NRAG
CSVKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPV-E---PP---------------------
--------SAAVEATNGAEQT--QVDKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGERRSNTAT-ETTTRHSQRAADGST
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-SGSPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

LHRMGAPGAAHTTCLSTVSQDALRFLAQRPPP-------------LTPG--GGSTLFPPR
RVSLGSLGNHPIPLLFPLRGQWGGR

PF12510 // ENSGT00760000118856_3_Domain_0 (86, 109)

LEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELEREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

QQREAEQRAALARLAGRLESMSDVEE-LTKLLRSASEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 988)

EIEAATLAGRLCSGHPNSGSTEDSK-GRA-ARRLERCEVPEQKEQE
QQAEVPE--STPTP-E-GTSHDVTTVTLLLSAPAGGTPSSP--ASPNSSPTTVSP-----
------EPPLEPAE-AQCSAAEAPGSPEPPPSPPKAT-STEPQESPASPSTERQVVNKLL
----SGPTEPPAAQ--SSTRDPSNTKRA--DLAGSGPCQRPLSVLKPR--------QPAQ
NR--------------------ESTPLASGSSPFQRA----------GSVRDRVLKFTFD
SPLAA-------RL-----RDGPPHAAL--------------------------------
---GSPISTRLLG------------------PSLTST----TPASS--SSGSSSHGPSDT
PSGFSKEQGRTARSLAQHRSCPPEEGPGGRGLAA---RPLENGAGGPVA-----------
---CSEEPSA------PLPVAVGI--AEPGGNMKT-TFTIEIKDGRGQASTGRVLLPTVN
QRAELTLGLRAPPTLLSTSSRGKNTITHVSGPGTLARP-GSVNHITSFSHASP-G-SQGG
CSIK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAEP-PSAAVETANGTEQT--RVDK

PF12510 // ENSGT00760000118856_3_Domain_2 (988, 1036)

APGGRSPLSTQELMAIEDEGVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1243)

KRDQRDKERERRLQEARARPGENRGNTAT-ETTTRHSQRAANGSA
VSTVTKTERLVHSNDGIRTARTTTVESSFVRRSENGSGS----S-TMQTKTFSSSSSSS-
-SKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-TVQRSTSFGVPNANSIKQMLLDWCRAKT

PF11971 // ENSGT00760000118856_3_Domain_3 (1243, 1343)

RGYQHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

---MRVHPRPHSRLVA-------KLAGLEPKTPYPGF--------LVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHSQQREAEQRAALARLAGQLDCEALVSM-R------------
--SLPSAAYGLRRLRVCAVTLAGRLCSVRPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGTPEPPPSPPKTT-SPEPQESPTLASTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---HSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGSKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKAL

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALAQLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATVAGRLCSGRPNSGSREDSG-GQA-AHRLDPCEVPEREEQE
QQTEVPDRAPTPTP-E-DTSQDMTTVTLLLRAPPGGTPSSP--ASPDSSPTTASP-----
------EPPLEPSG-DQCPATETPGSPEPPPSPSEA-PSPEPPMSSAPPSSEEQVVNKVS
----LDKNPSYV---------------V--SLLQLLPCPIQP----LT--------ALLF
LL--------------------ESIPLASGPSPIHRA----------GSVRDRVRKFVSD
SPVAV-------RL-----QDGPPRTAL--------------------------------
---ASLTPTRLLG------------------PSLIST----TPASS-N--SSSSRKPNDT
SSQFSKEQRGRAQPLAQLQSCPQP-PPAGRGLAP---RSLENQAGGPRA-----------
---CSEDPSV------PLPVA--IGTGEPGGSMKT-TFTIEIKEGRGQASTGRVLLPASN
QRAELTLGLRAPPSLLSSSSGGKSTISHVSTPGTMTRL-GSVTHVTTFSHASP-G-NRGS
CNIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSVAVEAANGAEQT--WVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLRAEELMAIEDEGVLDKMLDQTTSFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGESRSSTAT-ETTTRHTQRAADGSA
VSTVTKTERLVHSNEGTRTARTTTVESIVFSP----------------------------
-----SSIFDREDQTSPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGSPSAPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQHREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATVAGRLCSGRPNNSSREDSK-GLA-AHRLEQCEVPEHKEQE
QQAGVPE--PTPAP-E-DTSQDVTRVTLLLRAPPGDTPSST--ASPDNSPSTASP-----
------EPPLEPAG-APCAAAEAPGDPEPPPSTPRT-PTPDLPESLAQPSMEGQVANK--
---------------------------V--NLAGPQPCQRSLSVLSPQ--------RPAQ
SQGTAYSQRPPAPAVSCPTQPLTSTPLGSGPSPFHRA----------GSVRDRVRKFASD
SPTAA-------RL-----QDGPTRAAL--------------------------------
---GSLTPTRLLG------------------PSLIST----TSASS-SR-SSSSRGPSDT
SSEFNKEQRGTARPLAQLQSCPQEEGPRGRGLAA---RSLENRAGEPVA-----------
---CSEDPSA------PLPVA--VGTAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTSN
QRAELTLGLRTPPTLLSTSSGNKSTITHVNNPGTLTRM-GSVTHVTTFSHASP-G-SRGG
CSVKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSTAVEAANGAEQT--QADKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGERRSNTST-ETTTRHSQRAADGSA
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-S-GPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKDV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEGALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATLAGRLCSRLPSSGSREDSR-RQA-AHTLDPGKVPEEEKQG
QQTEVREPTP----TPEDTSQDVTTVTLLLRAPPGGTPSSP--ASPDSSPTTASP-----
------EPLLEPAG-AQCPAAEAPVSSEPLPHPSEA-PSPEPPMSPAPPSSQGRVISKPL
----LGSTEPSDTV--DSTRGSSNTKRA--DLAEPKPCQRSLSVLSPR--------QPTQ
NQ--------------------EPTPLAG-SSQFRRA----------GSVRDRVRKFTSD
SPVVA-------RL-----QDGPPRTAL--------------------------------
---ASPTPTRLPG------------------PSLMST----TLASSSSSSNSSSPSPSDT
SS--HKKQRELAHSLAQLQSCPQEEGPGGRSLAP---RSLENRAGGPRP-----------
---CSEEPST------PPPVA--VGTGEPGGSMKT-TFTIEIKDGRGQASTGRVVLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHVSSPGTVTRL-GSVTHVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PSATVEAANGTEQTLDKVNKGP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELMAIEDEGILDKMLDQATNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLREARARPGESRSNMATTETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTQTARTTTVESSFVRRSENGSSSSS--STTVQTKTFSSS---SS
SSKKMGSIFDREDQTSSRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-SGSPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1362)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
K-----------------------------CVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQE----NKENWLHAQHQEA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALTRLAGQLESMNDVEE-LTTLLRSAGKYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATVAGRLCSGQSNSGSREHSK-GQA-AHRLEQCEVSEPK-EE
QQAEIPE--PTPTP-E-GTGQDVTTVTLLLRAPPGDTPGST--ASPDNSPTTASP-----
------EPPLEPAG-AQCGAAETPGSPEPPPSTPRT-PTPEPPESLAQPNTEGQVVSKLL
----PGPTELPAAQ--APTRGPSNKNRA--NLAGPQPCQRSLSVLSPR--------QPAQ
NQ--------------------ESTPLASGPSPFQRA----------GSVRDRVRKFASD
SPTAA-------RL-----QDGPTRAAL--------------------------------
---GSLTPTRLLG------------------PSLIST----TSASS-SS-SSSSLGPSDI
SSQFSKEQKGIARPLAQLQSCPQEEGPRGRGLAA---RSLENSAGGPMA-----------
---CSEEPSA------PLPVA--VGTPEPGASMKT-TFTIEIKDGRGQASTGRVLLPTSN
QRAELTLGLRTAPTLLTTSSGNKSTIAHVSSPGTLTRM-GSVTHVTTFSHGSP-G-NRAG
CSVKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPV-E---PP---------------------
--------SAAVEATNGAEQT--QVDKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGERRSNTAT-ETTTRHSQRAADGST
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-SGSPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRTQPTPHSRLETE--------------------------------------CTHQK
GK

PF12510 // ENSGT00760000118856_3_Domain_0 (63, 109)

ELGASEMADEALAGLDEGSLRKLLEVTVDLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRSCC----------LCSSQQQEA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGRLESMSDVEE-LTVLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSRRPNSVSQEDSK-GRG-AHRLEQCEVPEREEQE
QQAEVLK--PTLTP-E-GTSQDVTTVTLLLRAPPGDTPSSP--ASLSSSPTTASP-----
------EPPLEPAK-AQCPAAKAPGSPELPRSPPKA-TSPEPQESPAPCSTEGQ----HL
----PDPTEPSAAQ--GPTRGPCDAKRA--DLAGPQPCQRSL-VLSPR--------QPAQ
NQ--------------------ESAPTASGPSPFQRA----------GSVRDRVRKFTSD
SPMAA-------RL-----QEGPPRAAL--------------------------------
---GPSTPARLLG------------------PSLAGT----TPASS--SKGSTSQGPTDT
SSRFSKEQRGIVQPLAQLRSCPQEEGPRRRGLAA---RPLENGAGGPVA-----------
---CSEEPSA------LLPVA--VGTAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHVSSPGTLARL-GSVTHITSFSHASP-G-SRGG
CSIKVS------------------------------------------------------
------------------------------------------------------------
----------------------------SSSLHQ---PHYPSTSH-RVLKG-VGLGRSME
PEPAEP-PSVAVEAANGAEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLRSEELMAIEDEGVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGEGRSNMAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MVQTKTFSSSSSSSS
SSKKMG------------------------------------------------------
-----SSPGGPRA-GVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1361)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNPLRRHELRLRGKNV

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADETLAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHFQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGRLESMNDVEE-LTALLRGAAEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 991)

EIEAATLAGRLYSGRPNSGSREDGQ-GQA-ARRLELREVPKPEEQK
QQVEVPE--PTPTP-S-STSRDVTTVTLLLRAPPGDTPSPP--ASADSSPTTTSP-----
------EPPLEPAEEAPCPAPEALGSPEPSPSPPRA-SSPEPQEPPATPSTDRQVVDKVS
----G-PHRPLSFLCPAPRGRYRLPTLP--DLADPRPCQRSLSVLSPR--------QPAQ
NR--------------------EPTPIASGPSPFQRA----------GSVRDRVRKFTSD
SPTAA-------GL-----QEGPPRVAL--------------------------------
---GPSTPARLPG------------------PSHTST----TPAAAS-S----SSG----
-----PSSRGTARPLAQLQSCPREEGPRGRGLAV---RSLENRAGGPVA-----------
---RSEEPSA------PLPVA--VGTAEPGASMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPALLSTSSGGKSTFTHISSPGNLARL-GSVTHVTSFSPASL-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSATVKVANGAEQT--RVDKAPG

PF12510 // ENSGT00760000118856_3_Domain_2 (991, 1036)

SRSPLSAEELMAIEDESVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGEGRGNTTT-KTSTRHSQQTADGSA
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGGGS----T-MTQTKTFSSSS----
-SKKMGSIFDREDEASPRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-ASSPGGPRM-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
-------------------------LEVTLDLAERRRIRSAIREIQRQELERDEGALASK
RFRAERLE----NKENWLHSQQQEEEQRVALALLSGKLEAISDVEE-LTTLLRAAGEYEE
RKLIRAAIRRVRAQEIEAATLAGRLSSTHEDSEGR-------A-ARRRARQ---------
---ELP------------------------------------------------------
------------------------------------------------------------
-------------------------------------SPRSLSLLTPR--------RA--
-Q--------------------APEASPASPSPFQRT----------SSVRDRVRKFTSD
PPAAL-------FGSGDRAAPGPLRASQQ--RPGL-------------------------
--TGSVKGEPSLP------------------SSFLIT----SKMSS-S----------TR
TSSW-QGEPQIVRVGARDRDCPKEEGPGGRSLSTSQGRPLENGERGPPP-----------
---GSEEP-S------TLPVT--TGRPELEANMKT-TFTIEIKDSRGQPISSRVLGPVGN
QRAELTLGLGAPPHFGGSST-GVGTIRHISTPGSXXXX-XXXXXXXXXXXXXX-X-XXXX
XXXXMD------------------------------------------------------
------------------------------------------------------------
----------------------------AEAMVE---TPT--------------------
------TVDLEVDTANGMEKS--RP-GNGAPQSKLCPEELATIEDETVLDRMLDQTTDFE
ERRLIRAALRDLRQRKRDQRDRERERRLQEARARPGEGRGSTAT-ETTTQQSQKSADGSA
VRTVTKTERLVHSSDGSQTSRTTTVESSFVKRSEXXXXX----X-XXXXX-XXXXX-XX-
-XXXXXXIFDREDETPSRAGSLAALERRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EG----SPAGSRG-TVQRSSSFGVPNANSIKQMLLDWCRAKTRGYEXXXXXXXXXXXXXX
XX-XXALVHFFPEAFDYGQLNPQNRRHNFEVAFSSAXXXXXXXXXXXXXXX-XXXXXXXX
XVL

PF00307 // ENSGT00760000118856_3_Domain_4 (1324, 1364)

VDC-----VPLVDVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRQKEL

---MRVHPRPHSRLVA-------KLAGLEPKTPYAGFE----SSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSRQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEQEEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASASSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGAPEPPPSPPKTT-SPEPQESPTLTSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGRSDT
SSRFSKEQQGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTCTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------MADETLAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHSQQRKAEQQAALARLAGRLESMSDVEE-LTTLLRGAAEYEE
RKLIRAAIRRVRAQEIEAATLAGRLCSGRPSSGSREDSK-GRA-AHRLDRCEVPKPEEQE
QQAEVPE--PTPTP-N-GTSHDVTTVTLLLRAPPGGTLSSP--ASAGSSPTTTSP-----
------EPPLEPAE-APRPATEALGGPKPPPSPPRA-ASPEPQEPPATPSTEGQVVNKLL
----PGPTEPSAAD--GPTKGLSDTKRA--DLAGPRPCQRSLSVLSPR--------QPVQ
NR--------------------EPTPLASGPSLFQRA----------GSVRDRVRKFTSD
SPMAA-------GL-----QEGPLRAAL--------------------------------
---GPSTPARLPG------------------SSHIST----TPASS-SR-GPSSRGPSDT
SSQFNKDQRGTARPLAQLQSCPREEGPRGRGLAV---RPLENRAGGPMA-----------
---RSEAPSA------PLAVA--VGTAEPGANMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELMLGLRAPPTLLSTSSGGKSTITHISSPGNLARL-GSVTHVTSFSHASP-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSAAVEVANGAEQT--RVDKAPERRSPLSTEELMTIEDESVLDKMLDQTTDFE
ERKLIRAALRELRQRKRDQRDKERERRLQETRARPGEGRGNTAT-KTTTRHSQQTADGSA
VSTVTKTERLVHSNDGRRTARTTTVESSFVRRSENGGGS----T-MMQTKTFSS---SS-
-SKKMGSIFDREDEASPRPGSLAALEKLQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-ACSSGGPRA-AVQRSTSFGVHNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAXXXXXXXXXXXXXXX-XXXXXXXX
XMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRIHPRPHRRLAA-------KLAGLEPETPYPGFE----FSELMTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSGRPNSGSREDSK-GRA-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTPASL-----
------EPPLEPAE-AQCLTAEVPGSPEPLPSPPKTT-SPEPQESPTLPSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTRLAIGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTSRAAL--------------------------------
---SPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRRVAQPLAQLRSCPQEEGPRGRGLAA---RPLENRAGGPVA-----------
---RSEEPGA------PLPVAVGT--TEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTHSTSLME
PEPAEP-LAAAVEAANGAEQT--RVSKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGQNPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTMRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRATSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELQREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

QQQEAEQRAALARLAGRLESMNDVEE-LTALLRGAGEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 985)

EIEAATLAGRLCSGRPNGGSREESK-GRA-AHRLEQCEVPEQEKQE
QHTEVPE--PTPTP-Q-GTSRDVTTVTLLLRAPPGGTPSLP--ASPVSSPTTASP-----
------EPPLEPAE-AQCPAAETVGSPEPPSSPPRAT-SPEPQEPPATPSTERQVVSKLL
----PGPTEPPAVQ--GPTKDPSNTKRA--DLAGSRPCQRSLSVLSPR--------QPAQ
NQ--------------------EPPNPASGPSPFQRA----------GSVRDRVRKFTSD
SPMAA-------GL-----QDGPPRLAL--------------------------------
---GASTPTRLLG------------------PSHINT----TPAS---SNGSSSRAPSDT
SSRFSKEPRGTARPLAQLQSCPREEGPRGRGLAA---RSLENRAGGPGA-----------
---RSEEPSA------PLPVPAGT--AEPGASMKT-TFTIEIKDGRGQASTSRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPATLAQL-GSVTHVTSFSHASP-G-SRRG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSAGPAHSSSLME
PEPAGP-PSAAVEVANGAEQT--Q

PF12510 // ENSGT00760000118856_3_Domain_2 (985, 1036)

VDKAPERRSPLSTEELMAIEDESILDKMLDQTTDFE
ERKLIRAALRELRQK

ENSGT00760000118856_3_Linker_2_3 (1036, 1232)

KRDQRDKERERRLQEARARPGEGRGNTAT-ETTTQHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGGGS----T-MVQTKTFSS--S-S-
-SKKMGSIFDREDEASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANSIK

PF00307 // ENSGT00760000118856_3_Domain_3 (1232, 1363)

QMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIKAATLAGRLCSRLPSSGPREDSR-RQA-AHTLDPGKVPEPEQQE
QQTEVLEPTP----TPEDTSQDVTTVTLLLRAPPGGRPSSP--ASPHSSPTSASP-----
------EPLLEPAG-AQCPAVEAPVSSEPLPHPSEA-PSPEPPMSPVPSSSRGRVISKPL
----PGPTEPSDTL--DSTSGFSSTKRA--DPAEMKPCQRSLSVLSPR--------QPTP
NR--------------------EPTPLAG-PSQFRRV----------GSVRDRVQKFTSD
SPVAA-------RL-----QDGPPRTAL--------------------------------
---ASPTPTRLTG------------------PSLIST----TPASSSSSSNSSSPSPSDT
SS--HKKQRELAHSLAELQSCPQEEGPGGRGLAL---RSLENRAGGPKP-----------
---CSEEPST------PPPVA--VGTGEPGGNMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHISNPGTVTRL-GSVTHVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PSTTVEAANGAEQA--RVDKGP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELTAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLREARARPGESRSNVAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTQTARTTTVESSFMRRLENGSSSST--TTTVQTKTFSSS---SS
SSKKMGSIFDREDQTSSRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGGPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIKAATLAGRLCSRLPSSGPQEDSR-RQA-AHTLDPGKVPEPEQQE
QQTEVLEPTP----TPEDTSQDVTTVTLLLRAPPGGRPSSP--ASPHNSPTSASP-----
------EPLLEPAG-AQCPAVEAPVSSEPLPHPSEA-PSPEPPMSPAPSSSRGRVISKPL
----PGPTEPSDTL--DSTRGFSNTKRA--DPAETKSCQRSLSVLSPR--------QPTP
NR--------------------EPTSLAG-PSQFRRV----------GSVRDRVQKFTSD
SPVVA-------RL-----QDGPPRTAL--------------------------------
---ASPTPTRLPG------------------PSLIST----TPASSS-SSNSSSPSPSDT
SS--HKKQRELAHSLAELQSCPQEEGPGGRGLAL---RSLENRAGGPKP-----------
---CSEEPST------PPPVA--VGTGEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHISNPGTVTRL-GSVTHVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PSTTVEAANGAEQA--RVDKGP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELTAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLREARARPGESRSNVAT-ETTTRHSQRAADGST
VSTVTKTERLVHSNDGTQTARTTTVESSFMRRLENGGSSSST-TTTVQTKSFSSS---SS
SSKKMGSIFDREDQTSSRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGGPGTPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1318)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTSDLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQHREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAKQLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATVAGRLCSGRPNSSSREESK-EQA-AHRLEQCEVPEHKEQE
QQTEVSE--PTPTP-E-DTSQDVTTVTLLLRPPPGDTPSST--ASPDNSPSTASP-----
------EPPLELAG-AQCAAAEAPGDPEPPPRTPRT-PTPELPESLAQPNMERQAANKLL
----PGSTEPPAAQ--SPTRGPSNKNRA--DLAGPQPCQRSLSVLSPR--------QPTQ
NQ--------------------ESTPLGIGHSPFHRA----------GSVRDRVRKFASD
SPMAA-------RL-----HDGPTRATL--------------------------------
---GSPTPTRLLG------------------SSVIIS----TTPASS-SRSSSSRGPSNT
SSESSKEQRGTTQPLAQLQSCPQEEGPRGRGLAA---RSLENRAGEPVA-----------
---CSEEPSA------PLPVA--VSAAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTSN
QRAELTLGLRTPPTLLNTGSGNKSTITHVSSPGTLTRM-GGVTQVTTFSHASP-G-SRRG
CSTKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPVQP--------------------------
-------PFTAVEAANGAEKT--QVDKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKEREQRLQEARGRPGERRSNTST-EMTTTHSQRAADGSA
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-SGSPGGPRT-GVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKDV

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADETLAGLDEGALRKLLEVTTDLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELEREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

QQREAEQRAALARLAGRLESMNDVEE-LTALLRGAAEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 987)

EIEAATLAGRLYSGRPNSGSREDSK-GQA-ARRLEPCEVPKPEEQK
QQVEVPE--PTPTP-S-SSSRDVTTVTLLLRAPPRDTPSPP--ASADGSPTTTSP-----
------EPPLEPAEEALCPAPEALGSPEPPPSPPRA-TSPEPQEPPATPSTDGQVVDKFP
----P-SPTEPPAA-QGPTKGRSDTKRA--DLADPRPCQLSLSVLSPR--------QPAQ
NR--------------------EPTPLASGPSPFQRA----------GSVRDRVRKFTSD
SPMAA-------GL-----QECPPRAAL--------------------------------
---GPSTPARLPG------------------PSHTST----TPAASSSS----SSG----
-----PSSRGTARPLAQLQSCPREEGPRGRGLAV---RSLENRAGGPVA-----------
---GSEEPSA------PLPVA--VGAAEPGASMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLISTSSGGKSTITHISSPGNLARL-GSVTHVTSFSPASL-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSAAVEVANGAEQT--RVD

PF12510 // ENSGT00760000118856_3_Domain_2 (987, 1036)

KAPGSRSPLSAEELMAIEDESVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1244)

KRDQRDKERERRLQEARARPGEGRGNTTT-KTSTRHSQQTADGSA
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGGGS----T-MMQTKTFSSSS----
-SKKMGSIFDREDEASPRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRM-AVQRSTSFGVPNANSIKQMLLDWCRAKTR

PF11971 // ENSGT00760000118856_3_Domain_3 (1244, 1343)

GYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
ETHADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

---MRVYPRPHSRLVA-------KLAGRPD-SCLSPAE----FSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMSDDALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAGQLESMNDVEE-LTVLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLYSGRPNSGSREDSK-GRV-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSRSP--ASPYSSPTPASP-----
------EPPLEPAE-AQCPTAEVPGSPEPPASPPKTT-SPEPQESPTPPSTEGQVANKLL
----SGRKETPAAQ--SPPRGPSDTKRA--DLARPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPIASGCSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---GPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQLGVAQPLAQLRSCPQEEGPRGRGLAA---KPLENRAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLTRL-GSVTHVTSFSHASP-G-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTSTARSTSLME
PEPAEP-PSAAVEAANGAQQT--QVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----STMVQTKTFS---SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-VCSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEGALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEGRCP------GLDP-PLYSDSE-KPW-LHPVGPLQVPKQEQQK
QQTEVPEPTPTPD-----ATQDVTTVTLLLRAPPGGTPSSP--TSPESSPTTASP-----
------EPLLEPAG-AQCPIAEAPDSSEPLPRPSGA-PSPEPPMSPAPPSSQGQIISKPL
----PDPTEPSTTL--GPARGSSDSKRA--DLAELQPCQRSVSVLSPR--------QPTP
NR--------------------ELVSLAR-SSQFQRA----------GSVRDRVRKFTSD
SPVAA-------KL-----QDGPPRAAL--------------------------------
---TSQTPRRLLG------------------SSCIST----TPASSS--SNSSSRGPSDT
SS--HKKQRELAHSLAQLQSCPQEEGPGGCGLAP---RSLENRARGPKP-----------
---CSEEPST------PLPVD--IGTGESGGSMKTTTFTIEIKDGRGQASAGRVLLPTGN
QRAELTLGLRTPPTLLSTSSGGKSTITHVSSPGTVTRL-GSVTHVTTFSHAAP-S-NRGS
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PSATVEAANGTEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELTAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKEREQRLREARARPGESRSNMAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTQTARTTTVESSFVRRSENGSSSSS--STTVQTKTFSSSS-SSS
KKMEVHPTVQR----------------IQGWEKAQLMTF-SWP--------------SSP
RHA-HSSPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1297)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSADPPLQPRHQ-------------SR
GPPPPC-----VPACPESSLHL---------------------------------

---MRVHPRPHSRLVA-------KLAGLEPKTPYPGFE----SSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLAAEVPGAPEPPPSPPKTT-SPEPQESPTLTSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFISD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPAS---SSGSSSRGRSDT
SSRFSKEQQGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTCTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFMRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-ASSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
-------------------------------------------MLIRQSSERDNGKLVCK
---------------------------------------SQDAVGNLVPSLAQEREDLEE
RQKIRAQIHELRSAQNGGSHIAGS----------K-----EIE-SNMLLRLKVPTKEQ--
----------LPSS-T-SSSS----------------------------STSSFT-----
------SFSSEPSSSSHCQATELLSLSAEFEGQPHNNR------------------NEVF
----M---EPSAEDSGTETREQPNTHVA-SHKQNVKSEQKPLPVWTGRADSHIISRLGAD
NK-ESFPE--GVTSASCS----E-PDDQTSMPPFRRA----------YSVRDRVKKFSEE
TSSVTTPALGF-RFGSMRAERAPVRGAHVLQQHSLLSVGQENNQKAAQNARFVTKQEVTR
TVSGPC-TRRLDGIPTAGTQSTN--KIQSFKSPFIPELNNSRSTSLKGSSSLSSTGPCTS
SREVNRGLP-------QSQGS--------FILKQNSGRSQENQLKVPLPMTERGRIDENS
DGANTEGPGSLQSSTHLCKSTKGTREETEDTDMKT-LLTIEIKDGRNQTTSSRVVGQPGN
QRAELMLGLTSSPFRINSGFST---SNDGASSGITTRSIRTETRTTT----QS-GITSSS
NVIKVE------------------------------------------------------
------------------------------------------------------------
----------------------------AETPQ---------------------------
----ETPQQLEVFLPST------TEKAEPENKGKLTAEDLNAIEEEEVLDKMLDKATDFE
ERKLIRAAMRDLRQRKREQREKEREQRLQELKNKERESKLARST-ETSIRQSETTNHGSA
VSTVTKTQRLVQSNDGSKTSSTTTLEASYMKRSENGDT-------IVQTKS-----SFSA
TSKKVGSIFDREDEGLSRANSMTAMERRQAERKKELMKAQSLPKTPATQARKAMIEKMEK
ESGGSSSPAFAKV-ATPRSAAFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCKAKTRGYEHVNIQNFSSSWSDG
MAFCALVHNFFPEAFDYNQLNPQNRRKNFDLAFSAA------------------------
EMLVDC-----VPLVEVEDMMIMGKRPDSKCVFTYVQSLYNHLRRHEMRLRKSEF

------------------------------------------------------------
--------MADEALAGLDEGALRKLLEV--------RIRSAIRELQRQELEREEGALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTILLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSRLPSSDSQEESR-RQA-AHRLDPGKVPEQEQQK
QQTEVPEPTPTPSPTPEDTSQDVTTVTLLLRAPPGGAPSSP--TSPDSSPTTASP-----
------EPLLEPAG-AQCPVAEALDSSEPLPQPSGA-PSPEPPLSPATPSSQGQVISKPL
----PDPTEPSTTL--GPARGSSNTKRA--DLTELQPCQCSVSVLSPR--------QPAP
NR--------------------EPAPLAR-SSQFQRT----------GSVRDRVRKFTSD
SPVAA-------RL-----QDGP-RTAL--------------------------------
---TSLTPTKLLG------------------SSCIGT----TPASS---SNSSSRGPSDT
SS--HKKQRELAHSLAQLQSCPREEGPGGRGLTP---RSLENRAGGPKP-----------
---CSEEPST------PLPVG--IGTGEPGGSMKTTTFTIEIKDGRGQASAGRVLLPTGN
QRAELTLGLRTPPTLLSTSSGGKSTITRVSSPGTVTRL-GSVTHVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PTATVEAANGTEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEERGPLSADELMAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDREREQRLREARARPGESRSNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTQTARTTTVESSFVRRSENGSSS----STTVQTKTFSSSS-SSS
SSKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGSPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRVHPRPHSRLVA-------KLAGLEPKTPYPGFA----EFSTGDGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-CTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGAPEPPPSPPKTT-SPEPQESPTLTSTEGQVVDKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGRSDT
SSRFSKEQQGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTCTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAS-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------MSQESLLG

PF12510 // ENSGT00760000118856_3_Domain_0 (77, 109)

MDEGALRKLLEATLDLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 144)

ELERDEETLASK
RFRPERSSHRQDDKENWPQSRHL

PF12510 // ENSGT00760000118856_3_Domain_1 (144, 195)

EEEQQAALTALSEQLEAITSVEE-LTKLLRAAGEYEE
RKLIRAAIRKLRAE

ENSGT00760000118856_3_Linker_1_2 (195, 986)

EIEAATLAGNLQSSQRDGSKIPPAVPGETKIVQRDNAETPALTGNE
ES--CGER-STKL--------------------PGTDKSGESSQQDDAEPALAGPEESGY
REAVEQSPAQEPKGSVPGPQARGCGG------------------AGACPSWEAGAVQPAS
WR-------SPETQCSGQEGTPSHSGGQGSRVPG-RGCRSRD-AL---------------
QAAAGFPSRASSHPQLWFQGPLCSWSCSQPQSPIQRLRIVP----------GRKGTWAV-
LPAPQSPVWHKAPEGSNSSQPSPVLAA---------------------------SQAV--
---AMPTPARELGARVRGTALAG-------------------------GGCCPSEEPMES
AGSWEDSGGVLPWPVSSQASVPTQEGGGGGGGGGGGGGGGGGGQRGPRTAPPAPAQNARG
SGGA---------EQRPAPRP----AGSRLDAMKT-FFTIEIKDGRVQPLAPRITAAPGS
QRAEVTLGLRSTPIRITTIPSSVSSICNISSVSS------NVTKGMDFGHVFGEPALEGG
YSSEME------------------------------------------------------
------------------------------------------------------------
----------------------------PEVVEQH-------------------------
-----QAPRREPELPNGMEKVQV--

PF12510 // ENSGT00760000118856_3_Domain_2 (986, 1036)

-REVEKRSKLNVEELSKIEDEDVLDKMLDRTTDFE
ERRLIRNAMRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1231)

KRDQREKERDQRLQEARSQSVAGRAGHAT-ETTTRQSTQSADGSA
CSTITKTERLVQSSDGTKTSRTTTMESSYVKRSDNGNST------FVQTKS-----SYSS
SSKKTGSVFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSASQARKAMMEKLQK
ESG-SSNPAASQT-TVQRSSSFGVPNANSI

PF00307 // ENSGT00760000118856_3_Domain_3 (1231, 1363)

KQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPDAFDYSKLTPQNRRQNFEVAFSSA------------------------
ETLVDC-----VPLVEVEDMMIMGKKPDAKCVFTYVQSLYNHLRRHELRMRQKEC

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQE----NKENWLHSQHQEA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALTRLAGQLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATVAGRLCGGRPNSGSREDSK-EQA-AHRLEQCEVSEHKEEE
-QAEVPE--PTPTP-E-GSSQDVTTVTLLLRAPPGDTPSST--ASPDDSPSAASP-----
------EPSLEPAG-AQCAAAEAPGSSEPPPSTPRT-PTPELSESLAQPNTEGQVVNEVS
----LDQG------------------QG--YLAGPQPCQRPLSVLSPQ--------QPP-
---------------------LTSTPLASGPSPFQRA----------GSVRDRVRKFTSD
SPTTA-------RL-----RNSPARAAL--------------------------------
---ASLTPTRLLG------------------PSLIST----TSASS-SS-NSSSRGPSDI
SSQFSKEQKGIARPLAQLQSCPQEEGPRGRGLAA---RSLENRAGGPVA-----------
---CSEEPSA------PLPVA--VGTAEPGGSMKT-TFTIEIKDGRGQASAGRVLLPTSN
QRAELTLGLRTPPTLLSTSGVNKNTITHVSSPGSLTRV-GSVTHVTTFSHASP-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPVQP--------------------------
-------PSAAVEAANGAELS--QVEKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

SQGQSPRSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGERRSDTAT-ETTTRHSQRAADGSA
VSTVTKTERLVQSSDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-SGSPGGPRV-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1319)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRVHPRPHSRLSA-------KLAGLEPETPYPGFE----FSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRAAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLYSGRPNSGSREDSK-GLA-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTPASP-----
------EPPLEPAE-AQCLTAEVPGSPEPPPSPPKTT-SPEPQESPTLPSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSQFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAA---RPLENRAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTSTTRSTSLME
PEPAEP-LAAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGERRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFLRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADDTLAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALAQLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEAATLAGRLYSGRPNGGSREDSK-GQV-AHRLEQCEVSEQVEQE
QQAEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSRSP--ASPYSSPTPASP-----
------EPPLEPAE-AQCPTAEVPGSPEPPASPPKTT-SPEPQESPTLPSTEGQVANKLL
----SGHKETPAAQ--SPPRGPSDTKRA--DLARPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---GPLTPKRLLG------------------PSLIST----TPASS--SSGSSSRGPSDT
SSRFSKEHRGVAQPPAQLQSCPQEEGPRGRGLAA---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQAST-------GN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLTRL-GSVTHVTSFSHASP-G-SRGG
CSIK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
REPAEP-PSAAVETANGAEQT--QVDKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRTPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGEGRSNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MVQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-ACSPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1362)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTVDLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELEREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

QQREAEQRAALAQLAGQLESMSDVEE-LTALLRGAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 985)

EIEAATLAGRLYSGRSNSSSREDSK-GRA-THRLERCEAPEREEQE
QQAEVPE--PTPTP-E-GTSRDVTTVTLLLRVPPGDTPSPP--ASPDSSPTTTSP-----
------EPPLEPAE-AQCPVAEALDSPEPPSSPPRAT-SSEPQEPPVAPSTEGQVVNKLL
----PGPTEPPAAQ--GPTKGPSDTKRA--DLAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------EPTPLASGPPPFQRA----------GSVRDRVRKFTSD
SPMAA-------GL-----QDGPPRAAL--------------------------------
---SSSTPARLLG------------------PSLIST----TPASS--S-SSSSRGPSDT
SSRFSKEQRGTAQPLAQLQSCRREEGPGGRGLAA---RPLENRAGGPVA-----------
---RSEEPSA------PLPVAVGT--AEPGASMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPGTLAQL-GGVTHVTSFSHASP-G-SRGG
YSIK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAEP-PSAAVEVANGTKQT--Q

PF12510 // ENSGT00760000118856_3_Domain_2 (985, 1036)

VDKAPERRSPLRAEELMTIEDESVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1231)

KRDQRDKERERRLQEARARPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERVVHSNDGKQTARTTTVESSFVRRSENGGGS----T-MVQTKTFSS--S-S-
-SKKMGSIFDREDEASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANSI

PF00307 // ENSGT00760000118856_3_Domain_3 (1231, 1363)

KQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKP-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALTRLAGRLESMNDVEE-LTTLLRGAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATVAGRLYSRHSNSGSGEDSK-GRA-AYRLEQHKVSEVKEQE
QQAEVPE--PTPTP-E-GTSQDITTVTLLLRAPPGGTPSSS--ASPNSSPTTASP-----
------EPSLEPAG-TQCPAAEAPGSPEPPPSSSGT-PRPDSPESPATLSTEEQVVTKLL
----PGPTKPPATQ--SPTRGPSNTKRA--DLASPQPCQRSVSVLSPH--------QPAQ
NQ--------------------ESTPLASGPSPFQRA----------GSVRDRVRKLTSN
SPTAA-------RL-----QDGPPRAAL--------------------------------
---GSPTPTKLLG------------------PSFIST----TPAAS-SN-SSSSQGPSDT
SSQFK--QRGTAQPLAQLRSCPQEEGPRGRSLAA---RSLENRAGGPVA-----------
---CSEEPST------QLPVA--VGIAEPGSSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPSTLLSTSSGAKSTITHVSSPGTLSRL-GSVTHVTTFSHSSP-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PETAET--------------------------
-------PSAAVETANGAEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEDLMAIEDEGVLDKMLDQATDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQREKERERRLQEARARPGEARSNTAT-ETTTRHSQRAADGST
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-TGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

-----------------------------------------------AGVKCTGDLTTRG
QTEVGASEMADDALAGLDEGALRKLLEVTVDLAERRHIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHLQQREAEQRAALTQLAGQLDSMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQEIEAATLAGRLCSGRPIGGSREDSK-GRP-AHRRERHEVPEQEEQE
QAG-APE--PAPTP-D-VTSRDVTTVTLLLRAPPGDTPSS---------PTAASP-----
------DPPLEPAE--------APGSPEPPS-PPE-DTSPEPQEPPAPLSTERQVVNKVS
----LDEGQGCQ------AVGYHPLSNL-PDLARPPPRQRSLSVLSPR--------QPAQ
NQ--------------------EPTHLASGPSPFQRA----------SSVQDRVRKFTSD
SPMAA-------GL-----QDGPRRAAL--------------------------------
---STPSPTRILS------------------PSLIST----TPASS--SSSSSLRGPSHT
SSRLIKEQPETARPLAQLQSCPREEGPRGRGLAP---RPLENRAGGPTA-----------
---RSEEPSA------RLPVA--ASTAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTSS
QRAEVTLGLRAPPTLLSTSIGGASTVTHVSSPGTPARL-GSITHVTSFSHAPT-S-NRGG
RSIKGT------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSSCRRHSSTGPAHSGSVME
PEPAQP-PSAGVEAANGTEQA--QVDKAPEQRSSLSAEELMAIEDEGILDKMLDQTTDFE
ERRLIRAALRELRQRKRDQREKERERRLQEARARPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDSTRTSRTTTVESSFVRRSENGSGS----T-MVQTKTFSSSS----
-SKKMGSIFDREDEASQRRSSVAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-TGSPGGPRT-AVQRSTSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
-----------------------------KCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEGALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTILLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSRLPSSDSQEESR-RQA-AHRLDPGKVPEQEQQK
QQTEVPEPTPTPSPTPEDTSQDVTTVTLLLRAPPGGAPSSP--TSPDSSPTTASP-----
------EPLLEPAG-AQCPVAEALDSSEPLPQPSGA-PSPEPPLSPATPSSQGQVISKPL
----PDPTEPSTTL--GPARGSSNTKRA--DLTELQPCQCSVSVLSPR--------QPAP
NR--------------------EPAPLAR-SSQFQRT----------GSVRDRVRKFTSD
SPVAA-------RL-----QDGP-RTAL--------------------------------
---TSLTPTKLLG------------------SSCIGT----TPASS---SNSSSRGPSDT
SS--HKKQRELAHSLAQLQSCPREEGPGGRGLTP---RSLENRAGGPKP-----------
---CSEEPST------PLPVG--IGTGEPGGSMKTTTFTIEIKDGRGQASAGRVLLPTGN
QRAELTLGLRTPPTLLSTSSGGKSTITRVSSPGTVTRL-GSVTHVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PTATVEAANGTEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEERGPLSADELMAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDREREQRLREARARPGESRSNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTQTARTTTVESSFVRRSENGSSS----STTVQTKTFSSSS-SSS
SSKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGSPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------RLAAE-------LARL-----------------ERGTPTLVWCYRHWG
RTELG

PF12510 // ENSGT00760000118856_3_Domain_0 (66, 109)

ALEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRPVSSTT--WPCQRWLRSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGRLESISDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 992)

EIEAATLAGRLCSGHPNSGSRDDSK-GRA-ARRLERREVPEREERE
QQAEVPE--STPTP-E-GTSHDVTTVTLLLRVPPGGTPSSP--ASPNSSPTAASP-----
------EPLLEPAE-AHCPAAEAPGSPEPPPSPPKA-TSPEPQESPAPPSTERPVVNKLL
----SGPTEPPAAQ--SPTRGPSDTKRA--DQAGSRPCQRSLSVLTPR--------QPAQ
NR--------------------ESTPLASGPSPFQRA----------GSVRDRVRKFTSD
SPLAA-------GL-----QDGPVRAAL--------------------------------
---GSLTPTRLLG------------------PSLTST----TPASS-SS-GSSSHSPSDT
SSRSSKEQGGTARPLGQLQSCPREDSPSGRGSAA---RSLENAAGGAVA-----------
---RSEESSA------PLPVA--IGTAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHVSGPGTLARL-GSVTHVTSFSHASP-G-GRGG
SGIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSAGTARSSSLME
PEPAEPS-SAAVEAANGAEQS--RADKAPGG

PF12510 // ENSGT00760000118856_3_Domain_2 (992, 1036)

RSPLSAEELMAIEDEGVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGDSRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSSS--SS-
-SKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

----------------------------MPDSCLSP----AEFSELVTGATGTGDLTR

PF12510 // ENSGT00760000118856_3_Domain_0 (59, 109)

KE
PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELEREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

RQREAEQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 984)

EKEAATLAGRLCGGRPNSGSREDSK-GRA-AHRLEQCEVPEREEQE
QQVEVSK--PTPTP-E-GTSQDVTTVTLLLRALPGSTSSSP--ASPSSSPTPASP-----
------EPPLETAE-AQCLTAEVPGSAEPPPSPPKTT-SPEPQESPALPSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGMPRAAL--------------------------------
---SPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRGGAQPLAQLRSCPQEEGPRGRGLAA---RPLENRAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGGMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSIK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAEP-LAAAVEAANGAEQT--

PF12510 // ENSGT00760000118856_3_Domain_2 (984, 1036)

RVNKAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1231)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
ESA-AGSPGGPRA-AVQRSTSFGVPNANSI

PF00307 // ENSGT00760000118856_3_Domain_3 (1231, 1363)

KQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

--------------------------------------------QLALGATGIGELTRRG

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

RTELGASKMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 142)

ELEREEEALASK
RFRAERQD----NKENWLHSE

PF12510 // ENSGT00760000118856_3_Domain_1 (142, 195)

QREAEQRAALARLARRLESMSDVEE-LTTLLRGAGEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 987)

EIEAATLAGRLCSGRPNRSSREDSK-GRA-AHRLDQSEVPKQEREQ
KVEA-----LKPPATPKATSQDGTTVTLLLRVPSGDTPSLP--ASPATSPTTASP-----
------EPPLEPAQ-AQRPAAEGPDSTES-PSSPGA-SSPEPQELPAPASTEEQVVNKLL
----PGPTEPTAAP--GPTGGPSHTKRT--DLQGARPCQHSLSVLSPR--------QPTQ
NR--------------------EPTPLAGGPSVFQRA----------GSVLDRVRKFTSD
SPMAS-------GL-----QDGPTRTAF--------------------------------
---SAQTPPKLLG------------------PSL--------------------------
------DQREAARPLAQLRSCPREEGPGGRGLAA---RPLENGAGGPAA-----------
---RSEEPSA------PLPVA--AGAAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPAGS
QRAELTLGLRAPPTLFSTSSGGTSTITHVSSPGNLARL-GSVTHVTSFSRASP-G-GRGG
CSIKTSCKGSDTASQRQQSLPLFPPSPHTAPGGTMPGVPGPGPELATALEERLGQALEEL
RAVAEAGRVAVTQAAEAAAAALEPVARAAEELRAETAALGRRLDALGRQVEVLSLRLGVP
L----EQELEPSELLLAAADPEALFEAAEDAGTPVAHPPAFSTCR-RSSAGPSHSGSLME
PEPVES-SSVVVEVANGAEQA--RVD

PF12510 // ENSGT00760000118856_3_Domain_2 (987, 1036)

KAPERRGPLSAEELMAIEDEGVLDKMLDQTTDFE
ERRVIRAVLRELRQK

ENSGT00760000118856_3_Linker_2_3 (1036, 1231)

KRDQRDKERERRLQEARARPGDSRSNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRRGAPRGGR-----------VVGHV-ARP
LSSASGSIFDREDQTSPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIQKLEK
EGP-AGSPGSPRV-AVQRSTSFGVPNANSI

PF00307 // ENSGT00760000118856_3_Domain_3 (1231, 1363)

KQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
K-----------------------------CVYTYIQEFYRCLVQKGLVKTKKS-

---MRVHPRPHSRLVA-------KLAGLEPKTPYPGFE----SSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEATADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSTPPNSGLREDSK-GRV-AHRLEQCEVPEPEEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLTVEVPGAPEPPPSPPKTT-SPEPQESPTLASTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SPTAA-------RL-----QDGTSRAAL--------------------------------
---SPLTPARLMG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRASSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRVHPRPHSRLVA-------KLAGLEPKTPYPGFAEFSKSSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 96)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRGGGG--------------GPLASK
RF----RD----NKENWLHSQQREAEQRAALARLAGQLDCEALVSM-R------------
--SLPSAAYGLRRLRVCAVTLAGRLCSVRPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGTPEPPPSPPKTT-SPEPQESPTLASTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---HSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGSKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKAL

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFMRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

----RAQFRPHSRL-A-------KLAGLEPGTPTLGLE----FRELVSGATSTGDLTRRG
RTEVGASKMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELQREEEALASK
RFRAERQD----NKENWLHSQQQEAEQRAALARLAGQLESMNDMEE-LTALLRGAGEYEE
RKLIRAAIRRVRAQEIEAATLAGRLCSGRPNSGSREETK-GRA-AQRLERCEVPEPETQE
QQAEVPE--PTPTP-Q-GTSRDVTTVTLLLRAPLGGTPSLP--ASPVSSPTTASP-----
------EPPLEPAE-AQCPAAEAAGSPEPPSSPPRAT-SPEPQELPATPSTERQVVSKLL
----PGPTEPPAVQ--GPTKGPSNTKRA--DLPGPRPCQRSLSVLSPH--------QPAQ
NR--------------------EPPTPASGSSPFQRA----------SSVRDRVRKFTSD
SPMAA-------GL-----QDGPPRLAL--------------------------------
---GSSTPTRLLG------------------PSHIST----TPASS--SSGSSSRGPSDT
SSRFSKEPRGTARPLAQLQSCPQEEGPRGRGLAA---RPLENGAGGPVA-----------
---RAEEPSA------PLSVPVGT--AEPGASMKT-TFTIEIKDGRGQASRSRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPGTLTQL-GSVTHITSFSHASP-G-GRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSAGPARSSSLME
PEPAEP-PSAAVEVANGAEQT--RVVRAPERRSPLSAEELMAIEDESILDKMLDQTTDFE
ERKLIRAALRELRQKKRDQRDKERERRLQEARARPGEGRGNTAT-ETTTQHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGGGS----T-MVQTKTFSS--S-S-
-SKKMGSIFDREDESSPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------MEDDAFAGLDEGALRKLLXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXXXXXXX--XXXXXXXXLKQREAEQRAALTRLAGQLESMNDVEE-LTTLLRGASEYEE
RKLIRAAIRRVRAQEIEAATLAGRLLSRRPTGGSKEDSE-GQP-AHRLEEHEXXXXXXXX
XXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX-----
------XXXXXXXX-XXXXXXXXXXXXX--XXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
----XXXXXXXXXX--XXXXXXXXXXXX--XLAGPHPCQRSLSIPSPR--------QPAH
NR--------------------EPTLLASGPSPFQRA----------GSVQDRVRKFTSD
SPMAA-------GL-----QDGPPRAAL--------------------------------
---HTPNPARIPG------------------PSFIST----TPASSSS--GSSLRGPSHT
SARLIKEQPGTARPLAQLQSYPQEEGPGRRGLAA---RPLENRAGGPTA-----------
---RSEDPSA------PLPMA--GSTAAPGASMKT-TFTIEIKDGRGQASTGRVLLPAST
QRAELTLGLRAPPTLLSTSSGGKSTVTHVSSPGTLARL-GSVTHVTSFSRASA-D-SGGG
CSIKIE------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAQL--------------------------
-------TSAAVETANGTQQA--RVDKTPEQRSPLSTEKLMAIEDEAVLDKMLDQTTDFE
ERKLIRAALRELRQRKRDQRDKERERRLQEARARPGEGRGNTTT-ETTTRHSQRAADGST
IGTVTKTERLVQSNDNTRTARTTTVESSFVKRAENGSGS----T-MVQTKTFSSSTSSS-
-SKKMG-IFDREDDTSLRRSSVAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGT-SGSPGSPRT-PVQRATSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VWLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------REQTHSSS-NLT
SVLSPSSIFDREDQTSSRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-SGSPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1304)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETLADCPQHPGYRGHRCALESLNW
KSRVQRTSQEFYPLSGPKGLVKQQKV-----------------------------

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADEAFAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELQREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

QQQEAEQQAALARLAGRLESMNDVEE-LTALLRGAGEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 985)

EIEAATLAGRLCSGHANSGSREESK-GRA-AQRLERCEVPEPEKQE
QQAEVPE--PTPPP-Q-STTRDVTTVTLLLRAPPGGTPSLP--ASPISSPTTASP-----
------EPPLEPAE-AQCPAAEAVGSPEPPSRPPRAT-SPEPQEPPATPSTERQVISKLL
----PGLTEPPAVQ--GPTKGPSNTKRAVLDLAGPRPCQRSLSVLSPC--------QPAQ
NR--------------------EPPTPAGGPSPFQRA----------GSVRDRARKFTSD
SPMAA-------RL-----QDGPSRLAL--------------------------------
---GSSTPARLLG------------------PSHIST----TPASS--SSGSSSRGPSDT
SSRPSKEPRGTARPLAQLQSYPREEGPRGRGLAA---RPLENGAGGPVA-----------
---RSEEPSA------PLPVPVSI--AEPGASMKT-TFTIEIKDGRGQASTSRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPGTLAQL-GSITHVTSFSHASP-G-SRGG
CSIK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAES-PSAAVEVANGTEQS--R

PF12510 // ENSGT00760000118856_3_Domain_2 (985, 1036)

VDKAPERRSPLSAEELMAIEDESILDKMLDQTTDFE
DRKLIRAALRELRQK

ENSGT00760000118856_3_Linker_2_3 (1036, 1244)

KRDQRDKERERRLQEARARPGEGRGNTAT-ETTTQHSQRAADGSA
LSTVTKTERLVHSSDGTRTARTTTVESSFVRRSENGGSS----T-MVQTKTFSS--S-S-
-SKKMGSIFDREDEASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANSIKQMLLDWCRAKTR

PF11971 // ENSGT00760000118856_3_Domain_3 (1244, 1343)

GYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIKAATLAGRLCSRLPSSGPREDSR-RQA-AHTLDPGKVPEPEQQE
QQTEVLEPTP----TPEDTSQDVTTVTLLLRAPPGGRPSSP--ASPHNSPTSASP-----
------EPLLEPAG-AQCPAVEAPVSSEPLPHPSEA-PSPEPPMSPVPSSSRGRVISKPL
----PGPTEPSDTL--DSIRGFSNTKRA--DPSETKSCQRSLSVLSPR--------QPTP
NR--------------------EPTSLAG-PSQFRRV----------GSVRDRVQKFTSD
SPVVA-------RL-----QDGPPRTAL--------------------------------
---ASPTPTRLPG------------------PSLIST----TPASSS-SSNSSSPSPSDT
SS--HKKQRELAHSLAELQSCPQEEGPGGRGLAL---RSLENRAGGPKP-----------
---CSEEPST------PPPVA--VGTGEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHISNPGTVTRL-GSVTHVTTFSHASP-G-NRGG
CNFK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PDPAEP-PSTTVEAANGAEQA--RVDKGP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELTAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLREARARPGESRSNVAT-ETTTRHSQRAADGST
VGTVTKTERLVHSNDGTQTARTTTVESSFMRRLENGSSSSSTTTTTVQTKSFSSSS-SSS
SSKKMGSIFDREDQTSSRPGSLAALERRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGGPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALALK
RFRAERQD----NKENWLHSQHREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTTLLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 990)

EIEGRRPAGEP-----------------W-LHPMGPPQVPEHKEEE
QQAEVSE--PTPTP-K-VTSQDVTTVTLLLRAPPGDTPSST--ASPDNSPTTASP-----
------EPPLEPSG-VLCAAAEAPGDPEPPPSTPRT-PN--LPESLTQPIMEGQVANKVS
----L-------------------QGQG--YLAGPQPRQRSLSVLSPR--------QPAQ
NQALL--------------SLLESTPLGSSPSPFHRA----------GSVRDRVRKFASD
SPMAA-------RV-----QDGPTRAAL--------------------------------
---GSVTSTRLLG------------------PSFIST----TPASS-SR-SSSSQGPSDT
SSEFNKEQRGITQPLAQLQSCPQEEGPRGRGLAA---RSLENRAGEPLA-----------
---CSEEPSA------LLPVA--VGATEPAGSMKT-TFTIEIKDGRGQASPGRVLLPTGN
QRAELTLGLRTPPTPLSTSSGNKNTITHASSPGTLTRM-GSVTRVTTFSHASP-G-SRGG
CSLKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPTEP--------------------------
-------PSTVLKATNGAEQT--QADKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

QGQSPLSTEELMAIEDEGVLDKMLDQSTDFE
ERKRIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPEERRSNTCT-ETTTRHSQRAADGST
VSTITKTERLVQSNDGTRTARTTTVESSFVRRSENGSGS----T-TVQTKTFSSSS-SS-
-SKKTGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-S-SPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1323)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 141)

ELEREEEALASK
RFRAERQD----NKENWLHS

PF12510 // ENSGT00760000118856_3_Domain_1 (141, 195)

QQREAEQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 984)

EIEAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTAASP-----
------EPPLEPAE-AQCLTAEVSGAPEPPRSPPKTT-SPEPQESPTLASTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVIGPRPCQRSLSVLSPH--------PPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSWGRSDT
SSRFSKEQRGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SQGG
CSVK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAEP-PSAAVEAANGAEQT--

PF12510 // ENSGT00760000118856_3_Domain_2 (984, 1036)

RVNKAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1244)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANSIKQMLLDWCRAKTR

PF11971 // ENSGT00760000118856_3_Domain_3 (1244, 1343)

GYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

---MRVHPRPHSRLVA-------KLAGLEPKTPYAGFAEFSKSSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHSRQREAEQRVALARLAGQLESMNDVEE-LTALVRPRLGQGM
G-HLPTTHL-PLAASLPAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASASSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGAPEPPPSPPKTT-SPEPQESPTLTSTEGQVVNKVS
----LGEGQGC----------------Q--DL--GRPCPTQLLT------------ALLF
LL--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SLMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGRSDT
SSRFSKEQQGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTCTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKAP

PF12510 // ENSGT00760000118856_3_Domain_2 (990, 1036)

EGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

-----------MSVPCR-------FLEL-----------------VSG-ATGTRDLTRRG
RTELGAI

PF12510 // ENSGT00760000118856_3_Domain_0 (68, 109)

VMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELQREEEALASK
RFRAERQD----NKENWLHSQQQEA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQQAALARLAGRLESMNDVEE-LTALLRGAGEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSGRPNSGSREESK-GRA-AHRLERCEVPEREKQK
QQAEIPE--PTPTP-Q-GTSRDVTTVTLLVQAPPGGTPSLP--ASPVSSPTTASP-----
------EPPLEPSE-ARCPAAEAVGSPESPSSPPRA-TSPEPQELPATPSTERQVVNKLL
----PGPTEPPAVQ--GPTKGPSDTKRA--DLAGPRPCQRSLSMLSPC--------QPAQ
NR--------------------EPTTLASGPSSFQRA----------GSVRDRVRKFTSD
SPMAA-------GL-----QEGPPRLVL--------------------------------
---GPSTPTRLLG------------------PSHIST----TPASS-SN-SSSSRGPSDT
SSRLSKEPRGTARPLAQLQSCPREEGPGRRGLAA---RPLENGAGGPVA-----------
---RSEEPSA------LLPVP--VGTAEPGASMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPGTLARL-GSVTHVTSFSHASP-D-SRGG
CGIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSAEVEVANGAEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PETRSPLNTEELMAIEDESILDKMLDQTTDFE
ERKLIRAALRELRQK

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGGGR----T-MVQTKTFSS---SS-
-SKKMGSIFDREDEASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-SGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADETLAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 142)

ELEREEEALASK
RFRAERQD----NKENWLHFQ

PF12510 // ENSGT00760000118856_3_Domain_1 (142, 195)

QREAEQRAALARLAGRLESMNDVEE-LTALLRGAAEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 987)

EIEAATLAGRLYSGRPNSGSREDGK-GQA-ARRLELCEVLKPEEQK
QQVEVPE--PTPAP-S-STSRDVTTVTLLLRAPPGDTPSPP--ASADGSPTTTSP-----
------EPPLEPAEEAPCPAPEALGSPEPPPSPPRA-SSPEPQEPPATPSTDRQVVLPAK
WVVVPGRLQHPRVQAL--------------SDTASSHCPRGVP-----------------
----------------------APRPAHSPPPPAQARWVDPLVNLLQGSLSESQGALQAY
SPLASG-----------KISPLPPRCPR--------------------------------
PPPGPPPPT-------HGERSPSPSAGRLWAPFLWPK-----------PSPSSWQCPCHP
----------GVSPRVGGGACERERGPQLSGGV-------AGGAGA--------------
----------------PLPWP--WAPAEPGTSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPGNLARL-GSVTHVTSFSPASL-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------PSATVKVANGAEQT--RVD

PF12510 // ENSGT00760000118856_3_Domain_2 (987, 1036)

KAPGSRSPLSAEELMAIEDESVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1244)

KRDQRDKERERRLQEAPPPPPGG---------GRRHSQQTADGSA
VSTVTKTERLVQSNDGTRTARTTTVESSFVRRSENGGGS----T-MTQTKTFSSSS----
-SKKMGSIFDREDEASPRSGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRM-AVQRSTSFGVPNANSIKQMLLDWCRAKTR

PF11971 // ENSGT00760000118856_3_Domain_3 (1244, 1315)

GYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
-----------------------------KCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------

PF12510 // ENSGT00760000118856_3_Domain_0 (69, 109)

MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALSRLAGRLESMNDVEE-LTTLLRSAAEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATVAGRLCSGRPTSGSREDSK-GRA-AHRLDRCEVLKREERE
QQTELSE--PKPSP-E-NTSQDVTTVTLLLRTPPEGTPSLP--AS----PTTASP-----
------EPLLEPVG-AQCPPAEAPGSPEPPPSPPGA-PSPEPPVPPASAGSERQVTNQLL
----PESTEAPAAP--GPTRGPCNTKRA--DLAGTPSCQRSLSVLSPR--------QPAQ
NQ--------------------ASTPLAGGSSPFLRS----------GSIQDRVRKFAPD
SPMAA-------RL-----QDGPSRAAL--------------------------------
---ASRTPTRLLG------------------PSLIST----TPASS-SSSSSSSRGPSDT
SSRFSKEQRGTAQPLAQLQSCPGEEGPRGRDLAA---GSLENRAGGPRA-----------
---CSEEPSA------LLPVA--VGTAEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGS
QRAELTLGLRTPPALLSTSSGSKNTVTRVSSPGALTRL-GSVTHVTTFSPATP-G-SRGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PEPAEP--------------------------
-------ASAAVEAANGAEQ-------T

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEARSPLSAAELTAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQK

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

K--------------------------------------------
------------------------------------------------------------
------RIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGSPGGPRP-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
--------MADEALAGLDEGALRKLLEATADLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHSQQREAEQQAALARLAGQLESMSDVEE-LTSLLRGAGEYEE
RKLIRAAIRRVRAQEIEAAALAGKLCSGHPNSGSREDSK-GRA-AHRLERYEVLEPERQE
QQTEVPE--PTPTP-E-VTSRDVTTVTFLLQAPPEGTSSSP--ASPNSSPTTASP-----
------EPPLESAK-AQCPASEALGSPKSPPSPPRA-TSPEPQEPPSSPSTEGPEVNKLL
----PGPIEPPAAQ--DPTRGPSNTKRT--DLAGLRPCQRSLSVLSPR--------QPAQ
NQ--------------------EPNPLASGPSPFQRA----------CSVRDRVRKFTSD
SPMAA-------GL-----QDGPPRATL--------------------------------
---GPSTPARLLG------------------PSQVST----TPASSSS--RSSSRGPSDT
SSQFNKEQQRTARPLAQLQSCPREEGPRGRGLAA---MPLENGARGREA-----------
---GSNEPSA------LLPVA--DGTAEPGASMKT-IFTIKIKDGRGQIPTGXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXLP-GDRGGG
CSIKME------------------------------------------------------
------------------------------------------------------------
----------------------------PELAEP--------------------------
-------PSATVEVANGAEQT--RVDKAPERRSPLSAEELMAIEDEGILDKMLDQTTDFE
ERKLIRAALRELRQRKRDQRDKERERRLQEARARPREGRGNMAT-ETTTRHSQQAADGSV
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGGGS----T-MGQTKTFSS---SS-
-SKKMGSIFDREDEASPRAGSLAALEKRQAEKKKELMKSQSLPKTSASQARKAMIEKLEK
EGT-VGSPGGPRP-AVQRSTSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MAAAFEERLSRALQEL
QAVAEAGRAAVTQAADAALATVEPVAQAAEELRAETAALSRRLDTLTRQVEVLSLRLGVP
LLPDLESELEPSELLLAAADPEALFQAAEDAGAPVAHPPAFSTRR-SSSVGPSRSSSLME
PDPAEP-PSVTVEAANGTEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMAIEDEGVLDKMLDQTTNFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDGSSSSTTVQTKT------------------------------
-------F-------------------SSS-------------------------S-SSS
SSKKMGSIFDREDQASPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGS-AGSPGTPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1362)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAETHADCPQLLDTEDM-VRLREPDW
K-----------------------------CVYTYIQEFYRCLVQKGLVKTKKS-

---MRVYPRPHSRLAA-------KLAGLEPETPYPGFE----FSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLYSGRPNSGSREDSK-GLA-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GTNQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTPASP-----
------EPPLEPAE-AQCLTAEVPGSPEPPPSPPKTT-SPEPQESSMLPSTEGQVVNKLL
----SGPKETPAAQ--STTRGPSDTKRA--DVAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAA---RPLENRAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTRSTSLME
PEPAEP-LAAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------VPEREERE
QQPEG----PKPSPAAESTSQNVTTVTVLLQAPHGATPSPP--ASPKTSPASASP-----
------EPPLEPAK-AQTPDAETLGSPELPASLPSA-TSPESQELPAPPSTEERVVNTLL
----PGPPEPPAAH--GPTRSLSDTKRT--XXXXXXXXXXXXXXXXXX--------XXXX
XX--------------------XXXXXXXXXXXXXXA----------GSVRDRVRTFTSD
SPRPA-------GL-----QHGPSRVAP--------------------------------
---GPLTPARLPG------------------SSFGST----TPASSSSGSSSRGTTDTSS
RS--SKEKPGTAQPLAQLQSCPREEGPRGRGLAA---RSLENGAGGARA-----------
---CSEEPST------PLPVA--VGTAEPGGSMKT-TFTIEIKDGRGQTAPSRVLLPTGS
QRAELTMGVRASPAILSTGGKGKSSITQTGNPGTPSRL-GSVTHVTSFSQASP-G-NRRG
CSIK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAEA-PAAAAEVANDTQQT--LGDKAPGRPSPLSAEELMAIEDEGVLDKMLDQATDFE
ERKLIRAALRELRQRKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----
XXXXX--XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXIFDREDETSPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGNAAGSPGTPRA-GVQRSTSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1320)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VLLREPDW
-------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------ER

PF12510 // ENSGT00760000118856_3_Domain_2 (992, 1036)

RSKLNVEELSKIEDEDVLDKMLDRTTDFE
ERRLIRNAMRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1231)

KRDQREKERDQRLQKREAS--CDRKGCHA-TETTTRSTQSADGSA
RSTVTKTERLVQSSDGTKTSRTTTMESSYVKKSDNGNRT------FVQTKS-----SYSS
SSKKTGSIFDREDESASRQSSLAALERRQAEKKKELMKAQSLPKTSASQARKAMMEKLQK
EGG-SSNPAASQT-AVQRSSSFGVPNANSI

PF00307 // ENSGT00760000118856_3_Domain_3 (1231, 1363)

KQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPDAFDYSKLTPQNRRQNFEVAFSSA------------------------
ETLVDC-----VPLVEVEDMMIMGKKPDAKCVFTYVQSLYNHLRRHELRMRQKEC

------------------------------------------------------------
--------M

PF12510 // ENSGT00760000118856_3_Domain_0 (70, 109)

ADETLAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGRLESMSDVEE-LTALLRGAPEYEE
RKLIRAAIRRIRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSGRPNSGSREDSK-GRA-SHRLERCEVLKPQEQE
HQAEVPE--PTPAP-N-GTSRDVTTVTLLLRAPLGSTPSSP--ASPESSPSTTSP-----
------EPPLESAK-AQGPAAEALGSPEPPPSPPRAP-SPEPQEPPATLNSDRQVVNKLL
----HCPTEPTAAQ--GPTKGLSDTKRA--DPAGPRPCQRSLSVLSPR--------QPVQ
NR--------------------EPTPLAGGPSPFQRT----------GSVRDRVRKFTSD
SPMAA-------GL-----QEGPPRGTL--------------------------------
---GPSTPARLPG------------------PSHTRA----TPASF-SSSGPSSRGPSDT
SSRFNKEQQGTA---SQLQSCPREDGPGGRGLAA---RPLENRAGGPVA-----------
---RSEEPSA------PLPVAVGT--AEPGASMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITHISSPGTVARL-GTVTHVTSFSHASP-G-SQGG
CSLK--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
PEPAEP-PSAAVEETNGAEQT--RVDKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PERRSPLRAEELMAIEDEGVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGEDRGNTAT-KTTMRHSQQTADGSA
VSTVTKTERLVHSNDGTRTART-TVESSFVRRSENGGGS----T-MMQTKTFSS--S-S-
-SKKMGSIFDREDEASPRPGSLAALEKRQAEK-KELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1362)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-THADC-----PQLLDTEDMVRL-REPDWKCVYTYIQEFYRCLVQKGLVKTKKS-

------------------------------------------------------------
--------MADEALAGLDEGALRKLLEVTSDLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHAQQREAEQRAALARLAGQLESMSDVEE-LTVLLRSAGEYEE
RKLIRAAIRRVRAQEIEAATMAGRLYSGRPNSGSREDSK-GRA-AHRLERREVPEPEERE
QQAQVPE--PTPTP-E-CTSQDVTTVTLLLRAPSGGTASSP--ASSDSSPTTVSP-----
------EPPPEAAK-ASCPVPEAPGSPEPPPSPHRA-TSPETQESPATPSTEGQVVNKLL
----PGPTEPPAAQ--GPIRGPSDTKRT--DLAGSRPCQDSLSMLSPR--------QPTQ
NR--------------------EPTPIASGPSPFQRA----------GSVRDRVRKFTSD
SPMAA-------RL-----QDGPSRIAL--------------------------------
---GSSTPARTLG------------------SSLTST----SLASSSSSSGSSSRGPSDT
SSRFNKELRGTAQPLAQLQSCPQEEGPRGRGLTA---RPLLNRAGGPPA-----------
---NSEEPSA------LLPVT--VGTAEPGSSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX----------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------XXXXXXXXXXXXME
PEPAEP-LSTAVEVANGAEQTQSRGDKAPEGRSLLSTEELMAIEDEGVLDKMLDQTTDFE
ERKRIRAALRELRQRKRDQRDKEREQRLQEARARPGDGRGNTAT-ETTTRHTQRAADGSA
VSTVTKTERLIHSNDGTRTARTTTVESSFMRRSENGSGS----T-TVQTKTFSSSSSSS-
-SKKMGSIFDREDQTSPRPGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLXX
XXX-XXSPGGPRV-AVQR-TSFGVPNAN

PF00307 // ENSGT00760000118856_3_Domain_3 (1229, 1364)

SIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTEDM-VRLREPDW
KMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRAQPRPHGRLVAE-------LAWL-----------------EPGTPTLVWCHRHWG
RTELG

PF12510 // ENSGT00760000118856_3_Domain_0 (66, 109)

ALEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASK
RFRAERQD----NKENWLHSQQREAEQRAALARLAGRLESISDVEE-LTTLLNTHGLPL-
----TCSCEAVGALSWPPATLAGRLCSGHPNSGLREDSK-GRA-ARRLERCEVPEQEERE
QQAEVPE--STPTP-E-GTSHDVTTVTLLLRAPPGGAPSSS--ASPNSSPTTASP-----
------EPPLEPAK-AHCPAVEAPGSPEPPPSPPKA-TSPDPQESPAPPSTQRQVVNKLL
----PGPTEPPAAQ--SPTRGPSDTKRA--DLAGSRPCQRSLSVLTPR--------QPAQ
NR--------------------ESTPLASGPSPFQRA----------GSVRDRVRKFTSD
SPLAA-------GL-----QDGPPRSAL--------------------------------
---GSLTPTRLLG------------------PSLAST----TPASS-SS-GSSSHSPSDT
SSRFSKEQRGTAQPLAQLQSCPREDSPGGRGLAA---RSLENGAGGAMA-----------
---RSEEPGV------LLPVA--VGTAEPGGNMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKNTITHVSGPGTLARL-GSVTHVTSFSHASP-G-GRGG
CSIKVS------------------------------------------------------
------------------------------------------------------------
----------------------------PSSPHQ---PHHPSTS-----HRPCKGVGLME
PEPAEPPSAAPSEAANGAEQT--RADKAPGG

PF12510 // ENSGT00760000118856_3_Domain_2 (992, 1036)

RSPLSAEELMAIEDEGVLDKMLDQTTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARARPGDSRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSSS--SS-
-SKKMGSIFDREDQASPRPGSLAALEKRQAEKKKEMMKAQSLPKTSASQARKAMIEKLEK
ESA-AGSPGGPRT-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSA------------------------
EMLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRVHPRPHSRLVA-------KLAGLEPKTPYAGFE----SSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSRQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLCSARPNSGLREDSK-GRV-AHRLEQCEVPEREEQE
QQTEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASASSSPTAASP-----
------EPPLEPAE-AQCLTAEVPGAPEPPPSPPKTT-SPEPQESPTLTSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPH--------QPAQ
NR--------------------ESTPLASRPSSFQRA----------GSVRDRVHKFTSD
SLMAA-------RL-----QDGTPRAAL--------------------------------
---SPLTPARLVG------------------PSLTST----TPASS--SSGSSSRGRSDT
SSRFSKEQQGVAQPLAQLRSCSQEEGPRGRGLAP---RPLENGAGGPVA-----------
---RSEEPGA------PLPVAVST--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSVKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTCTTRSTSLME
PEPAEP-PSAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQTSPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV

---MRVHPRPHSRLAA-------KLAGLEPETPYPGFE----FSELVTGATGTGDLTRKE

PF12510 // ENSGT00760000118856_3_Domain_0 (61, 109)

PTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQ

ENSGT00760000118856_3_Linker_0_1 (109, 146)

ELEREEEALASK
RFRAERQD----NKENWLHSQQREA

PF12510 // ENSGT00760000118856_3_Domain_1 (146, 195)

EQRAALARLAGQLESMNDVEE-LTALLRSAGEYEE
RKLIRAAIRRVRAQ

ENSGT00760000118856_3_Linker_1_2 (195, 989)

EIEAATLAGRLYSGRPNSGSREDSK-GLA-AHRLEQCEVPEREEQE
QQAEVSK--PTPTP-E-GTSQDVTTVTLLLRAPPGSTSSSP--ASPSSSPTPASP-----
------EPPLEPAE-AQCLTAEVPGSPEPPPSPPKTT-SPEPQESPTLPSTEGQVVNKLL
----SGPKETPAAQ--SPTRGPSDTKRA--DVAGPRPCQRSLSVLSPR--------QPAQ
NR--------------------ESTPLASGPSSFQRA----------GSVRDRVHKFTSD
SPMAA-------RL-----QDGTPQAAL--------------------------------
---SPLTPARLLG------------------PSLTST----TPASS--SSGSSSRGPSDT
SSRFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAA---RPLENRAGGPVA-----------
---RSEEPGA------PLPVAVGT--AEPGGSMKT-TFTIEIKDGRGQASTGRVLLPTGN
QRAELTLGLRAPPTLLSTSSGGKSTITRVNSPGTLARL-GSVTHVTSFSHAPP-S-SRGG
CSIKAA------------------------------------------------------
------------------------------------------------------------
----------------------------EDAGTPVAHPPAFSTRR-RSSTGTTRSTSLME
AEPAEP-LAAAVEAANGAEQT--RVNKA

PF12510 // ENSGT00760000118856_3_Domain_2 (989, 1036)

PEGRSPLSAEELMTIEDEGVLDKMLDQSTDFE
ERKLIRAALRELRQR

ENSGT00760000118856_3_Linker_2_3 (1036, 1230)

KRDQRDKERERRLQEARGRPGEGRGNTAT-ETTTRHSQRAADGSA
VSTVTKTERLVHSNDGTRTARTTTVESSFVRRSENGSGS----T-MMQTKTFSS--SSS-
-SKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSASQARKAMIEKLEK
EGA-AGSPGGPRA-AVQRSTSFGVPNANS

PF00307 // ENSGT00760000118856_3_Domain_3 (1230, 1364)

IKQMLLDWCRAKTRGYEHVDIQNFSSSWSDG
MAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAE-----------------------
-MLVDC-----VPLVEVDDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV