Query Results 

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----------------------------------------------------CS-PGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHWDCAQGEDEDQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CSFEDGFCGWSQGTLSP-HAPQWQVKTLK-EARFQDRQGHALLLNTTEVPTSAS
AT-VTSSTFPA-PMKNSP-CELRMSWLIQGVLRGNVSLVLVENRTGKEQSRMVWHVAT--
--NEGLSLWQWTVLPLLDVTDRFWLQIAAWWERGSRATVAFDNISISLDCYLTISGEDKM
LQ-----NTAPKSRNLFER-----NPNKEMKLWENT------PRETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNTNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGR
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGYS-GAAGKAVKLGLRMGTLWPSQQ---------HSRRVIRAWSSSTRTGF
GGGGGGCSSGGGGGGYIGGNAASDNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEGDECHLDPESHQVICFCDHGTVLAEDGVSCVVSPT-PEP--RL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFATIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSPPAGK
GGDRQDPA---ALAPLPST-SSGKAVRKPPA-------PE-VNVPVARGPAVGGGHINMA
FAQSNP-PSELHKVQRSRNKPTSLWNPTYGSWFTEKPARKARPPAQK---EPER---GGP
GPGGP--VPPSA--AAGRVPG----ASLLLEPSSLTASVKEVPLFRLRHFPCGTVNYGYQ
QQGLPLEATA----P-GAGHYEDTALQSQPGP-----

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------------------------------------------------WTRRLICCRSPI
LICFVIRVFQHNLSQLKCFWFRQK------------------------------------
---------------------------------------------------MAAIHKLL-
MPPSSSFSYIPLPLES---LDKLR-CRYHLEFHPLVPMKNVGPEIC--------------
--------------TGAGPLCRLDLLLITV----------FL------------------
--CSSSLLSNATSWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSL
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQAEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENGFCGWTQSSLSR-HMPQWQVKALQ-DAQTQDHQGHALVLSTTDAPTSAS
AT-VTSAAFPP-PMKSSP-CELRMSWLIRGVLQGNVSLVLVENKTGKEQSRMIWQVAT--
--IEGLNLWQWTVLPLLDVADRFWLQIVAWWGQGSRATVAFDNISVSLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKL
PQN----T-APKSRNLFER-----NPNKEPKAWEN------TPGETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1064)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFI

ENSGT00760000118818_8_Linker_5_6 (1064, 1236)

N-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPQL
PLSLILSVVTSALVAALVLAFSGVMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPMRPKDPEGIPPLLVAAPQPR
REEGP---EPAAPPPPPAA-SSGKAGKKAAAAEL-------AVRG-PRGAAADGGHVNMA
FAPSSA-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTPKNSPPA--KREPPGR---GSL
GREGS--CGGPSAAAPGRLPG----AALLLEPSSLTADVKDVPLFRLRHFPCGTVHYGYQ
QQGFPPEAAP----G--RSPDP--ALKG-----QAAP

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-------------------------------------------LQRKSLTVDFIVPS-LF
RIXXXXXXXXXXXXX----XXXXX--------XXXXXXXXXXXXPFLSQRSRYGFECNF-
DFPCELEYSPPVQEDR---NHHWSWRHITSEEASQMNLFSGGPEVIQSEEMPRGSFLLLN
TSENTKHTILSPWMRSNSEHCTMEVSVYRDLQTSGRYMAQLLPHNEARRE----------
--IVLVPNPEKYGWTVLHGRIGYLQSPFRVSLEYISSANRSLSVVDSLSLKNCS-EGMPP
ISKMALKSSFTCWNGTTIHLG------------------QACNFQRDCSEGEDEGELCXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXX
XX-XXXXXXXX-XXXXXXXXX

PF00629 // ENSGT00760000118818_8_Domain_2 (622, 712)

LQFSWLIHGVLEGNISLMLMENKTGKEQSRTIWYFAN--
--SEGLGIWHRMVLPLSDTSDRFWLQIVTWWEEGSGALIAFDNISLSLDCYLTINGEERI
SR-----DEAPNSRNLFEN-----IYKKSPQE---PRSLENGHGENLNFDPTVHWLFTTC
GASGPQGPTQTQCNNAYRNSNLSVVVGSEGALKGVQIWRVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGVFDLEKDDFLYILVGQQGGDACPSTNEIIQKVCIG------ENNVIE
EEIRANQSVTEWAGGGGGGGGATYIFKMKNGIPVPLIIAAGGGGRAYGAKTDTFHPEKLE
NNSSVLGLNGIS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAVNNDPE--V---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKLYLNCSHCEMDECRIDPESHKVICFCEHGTVLAEDEVSCIVSPT---SEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ISLIRGLGHGAFGEVYEGQVSGSPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCS
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHLPEDRPNFATIL
ERIEYCTQ-DPDV--VNTALPVEYGPVTE-----EEEKVPMRPEDPDRIPPLLVSPQQEK
KEDVCPPS---VPPPLPTT-SSGKPLKKAMA-------LE-PPVRITRGIPVEGGHVNMA
YSQSNP-PTELHKGRGSRNKPT--------------------------------------
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-------------------------------------

MGA---IGLMWLLLLLSPA----------A-SGSGTGTETGQRVGSPAMGSALQPREPLS
YSRLQRKSLTVDFVVPSLFRVYARDLLLPPL----SPSEPRAGRLEARGSLALDCAPLLR
LVGPPPGAS----SP--APARAWTLSRVLKEGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EATAGLLQFNLTELFSWWIRHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFATGTGQSSLESPANLPSLPPDSLA------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHNLG---NQSWSWRRVPAEEASQMDLL-DGPEEEHAKEMPRGAFLLLN
TSMNSRHSILSPWVRSSSEHCRLAVSVHRHLQPSGRYVARLLPHSEA-GR-------EIP
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CNFEDGFCGWTQSSLSP-HTPQWQVRTLK-DARFQDHQGHALLLSTTDAPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLQGNVSLVLVENKTGKEQSRMIWHVAT--
--TEGLSLWQWTALPLLDVADRFWLQIVAWWEQGSRATVAFNNISISLDCYLTIGGEDKM
LQN----T-APKSRNLFEG-----NPNKETKPWES------TPKENPVFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDVLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNKSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAVKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIN-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHRVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF00069 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPMRPKDPEGIPPLLVSAPQAK
REEGR-EPAAR--TALPST-SSGKAGKKPVAA--------EASARGARALAVKGGHVNMA
FSQSNP-PSELHQVQGSRNKPTSLWNPTYGSWFTEKPTKKSNPPA--KKEQRER---GNP
GGEGGRAILP-P-AAAGHRPG----TSLLLEPSSLTTSLRDVPLFRLRHFPCGTVHYGYQ
QQGFPPEAA-----APGPGRYEDPGKSQ------PAP

---MGAIGLLWLLLPLLSKAASG----------SGTGTETGQRVRSPATGPALQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLQPP----FPSEPRAGQLEAHGSLALDCAPLVR
LVGPPPGVSWTTGGGSPAPAPAQTLSRVLKGGSVRKLRRAKQLVLELGEEAIFEGCIGPP
D-EATVGLLQFNLSELFSWWIRHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSVESPTNVPSLSPNS------FAWNLTWIMKDSFPFLSHRSRYGLECIF-
DFPCELENSPPLHXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXSFLLLN
TSANSKHTILSPWMRSSSEHCRLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSK
LPAGFF

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CNFEDGFCGWTQNSLLP-HTPQWQVKTLK-DAQFWDHQGHALLLSTTDTPTSES
AA-VTSATFPA-PLKNSP-CELRMSWLIRGVLQGNVSLVLVENKTGKEQSRIIWHVAT--
--IEGLSLWQWTVLPLLDVADRFWLQIVAWWGPGSRATVAFDNVSISLDCYLTISGEDKL
PQN----T-APKSRNLFER-----NPNKEPKPWEN------TPRETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXX
XXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXGGGGWSDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIXXXXXXXXXXX--X---XXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXX-XX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXVCSEQDELDFLMEALIIXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXXXXXXS

PF07714 // ENSGT00760000118818_8_Domain_7 (1337, 1368)

QPSSLAMLDLLHVA-DIACGCQYLEENHFIH

ENSGT00760000118818_8_Linker_7_8 (1368, 1434)

RXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF07714 // ENSGT00760000118818_8_Domain_8 (1434, 1503)

SFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPTRPKDPEGLPPLLVSAPPAR
REEGREP---AAPPALPSA-PCGKAGKKVLAAA-------EGSGRAPPGPAAEGGHVNMA
FAQSSL-PSEPHKVQGSRNKPTSLWNPTYGSWLTEKPTKKTNPPA--TAEPHGR---GHP
GREGGR-----ADAAAGRLPG----ASLLLEPSSLTATIKDVPLFRLRHFPCGNVNYGYQ
QQGLPLEAA-----GPGPGRYEDPGLKSQ-----PGP

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-----SPKPGEVNWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHRDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLNLWQWTVLPLLDVSERFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 829)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGET------SPRQTPIFDPTVHWLFTTC
GAQL----------------------GEKNPFLQGLIWGRT-LRPRRI

PF12810 // ENSGT00760000118818_8_Domain_5 (829, 1066)

SGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1338)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHQVICFCDHGTVLAEDGISCIVSPT---PEPHL
PLSLILSVVTSALV------------------VHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPND
PSPLSGSL----------------------------------------------------
-------------LSLQ

PF07714 // ENSGT00760000118818_8_Domain_6 (1338, 1502)

PSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLAE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
EEER--S--PAAPPPLPTT-SSGKAAKKPT-AA-------GVSVRVPRGPAMEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKK--------KEPHER---GNL
GLEGSCTVPPNV--ATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

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-VP----FTPKHIWTVLQGRVGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCSQGEDEGQLCSN
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENDFCGWSQGILSP-HTPRWQVRSIK-DSRYQEHQGHSLMLSTTDVPTSEN
AT-VTSTTFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRRIWHVTT--
--DEGLSLWQWTVLPLLDVTDRFWLQIVAWWGQGSRATVAFDNISVSLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDRM
FQN----AEEPKSRNLFDR-----NSHKEPKAEEN------ASRETHTFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSANQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKIKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPKSHKVICYCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTVM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLTMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GTGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLLE-----EEEKVPMRPKDPEGMPPLLVSPQQAK
QEER--GPAAPAP--LSTA-SSGKAVKKPTAS--------EVSVRVPRGLPMEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPAKKNNPPT--KKEPHEK---RSL
GREGGCTVPA-N-VATGRLPG----ASLLLEPSALTASMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA----APGASQYEDTILKSKSNVNQPGP

---MGALGLLWLLSLLLLA------------AASDSGAATDQRSGFLAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PPSPSEPGASGLEARGSLALDCAPLLR
LLGPPPGVSWADAASSPSPEVGSTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCIGPP
EEATAVGILQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSTAIRASQPRLLF
QIFGT--GRSSLESPSGMPSPPDN-------FVWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRRVPSEEASQMDLL-NGPEAERSKGTPRGSFLLLN
ASADSKHAILSPWMRSNSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAGRE----------
--ILLVPTPGKHGWTILHGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGPLLP-HLPRWQVRTLK-DAHSRDQQGHVLLLSTTDVPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIHGVLNGNVSLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQWTVLSLLDVTDRFWLQIVTWWGPGSGATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
PSN----A-APKSRNLFEK-----NPNKDPKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
HEEVP---AAPQPAALVA---PGPLVKKPPGAGAGAG--AGAGAGRAPRGAADRGHVNMA
FSQPNPP-PELHKSAGSRNKPTSLWNPTYGSWFTEKPAKKTHPP------PGAE---PQ-
ARAGAAEGGWTGPGAGPRRPG----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAT-----AAP----GDTVLKSKNKVTQPGP

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-------GHSSFESPTSMPSPHLDSFA------WNLTWVMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHEHG---NHSWSWRQVPSEEASQMDLL-DGPEAEYSKEMPRGSFLLLN
TSANSKHTILSPWMRSSSENCTLAVAVHRHLQPSGRYVAQLLPHNEA-GR-------EIL
LLP----TPSAISWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
ASKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSN
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CDFEDGFCGWTQGTLLT-HTPRWLVRTLK-DARVQGYQGQSLLLSTTDVPMSES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNISLVLVENKTGKEEGRMVWHVAT--
--NEGLSLWQWMVLPLLNVSDRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEDKM
PQN----T-APKSRNLFER-----NPNKELKPWEN------TPRETQIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVMVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTSQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPMPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLPWSGKSLLEGAIGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKI--------SSISDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGMPND
PGPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLME-----EEEKVPMRPKDPEGIPPLLVSPQQAK
REGEH-CPTAPPP--LPST-SSGRAGKKAAGA--------EVCVRGPRGPAGEGGHVNMA
FSQSNP-PTEVHKVQGSRNKPTSLWNPTYGSWFAEKPAAKKNDPVAARKQQREQ---GKA
GREGGCTAPP-S-AAAGRLAG----ASLLLEPSSLTASIKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA----APGTSNYKDSILKNKNV-TQPGP

------------------------------------------------------------
------------------FRAYVRDLLLPP--------EPRAGLTEARGVLALDCAPLLR
LLGPPSGVSWA--------SPVPALSRVLKGGSVRKLRRAKQLVLELGEESILEGCLGPP
R-EAAAGLLQFTLSELFSWGIRHGRGRLRIRLMPEKKASEGGREGRLSTAIRASQPRLLF
QILGAXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXLECSF-
DFPCELEYFPPLHDRG---NQSWSWRRVPPEEASQMDFL-DGPEAERAKDMPRGSFLLLN
TSAESKHTILSPWMRSSSEHCTLAVSVHRHLQPTGRYVAQLLPHNEPGRE----------
--ILLVPTPGKHGWVLRKI----------------------------EPEHHRV-AEYIS
GRSSAVDSRLDCSEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXK
LPTGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CKFEDGLCGWTQDTLSS-QGPRWQVRTMK-DARSQAHQDHALLLSTTEVATSES
AT-VTSATFPA-PMKNSP-CELRMT-LVRGALRGNVSLLLVEK-TGKE-QRMLWHVPP--
--SNGLSL-QWVVLPLLDVSDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTISGEDKM
PL-----NAEPKSRNLFEG-----ISNKDLKP-------REPTPGTPTFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNQSVVVGSEGPLKGIQIWTVPATDTYXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGEDACPATNQLIQKVCIG------ENKVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXGNAASNNDPE--M---DGEDGISFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEIDECHMDPETHKVICFCDHGTVLAQDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQLELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGMPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDIAARNCLLTCP
GTGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTS-TDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPMRPKDPEGVPPLLVSPAQAT
REEVPAPA---APPALPATSSA--RVAKKPA-------AAEVPARGPRGSAMEGGHVNMA
FAQSTV-PSELPKGQASRNKPTSLWNPTYGSWFTEKPARKNNALAKKE--PQDR---GHQ
GHEGSCTVSPGV--AAGSPPAASRGAPLLLEPAA--------------------------
-------------------------------------

MGP---IGLLWLLPLLLST------------AALGSGTGAGQRLGSPAAGLQLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-S----SPSELKAERPEARGSLALDCAPLLR
LLGPPPGVSWTMGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGSP
G-EAAAGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPRNMPSPSPDHFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDFL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDSPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESHMCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQIRTLK-DARFQDHQDHALLLSTTDVATSES
AT-VTSATFPA-PMKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEHGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PQK----T-APKSRNLFER-----NPNKELKPGEN------SARQNPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSHQVKR
GEEER-GPAAPPP--LPTT-SSGKATKKPTAA--------EVSVRVPRGPTVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTLLKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------S-AGLPL
SSKMALQS

PF00057 // ENSGT00760000118818_8_Domain_1 (489, 538)

SFNCWNGMTIKLG------------------QVCDFTRDCAEGEDEGQQ

ENSGT00760000118818_8_Linker_1_2 (538, 547)

CKN
LPPGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFENGDCGWTQSSPTSQEIHFWHIGNPK-NKHFCLLKECALLLNTSETPVTEA
VV-MTSAVFPA-PMKNSP-CELRMAWFLHGILLGDVSLFLVENKTGKEHSRKLWHFEN--
--RKGLGVWQKMVRPLIDVSDRFWLQIITSWKVGSEAIIAFDNVSLSLDCYLTKRGFISG
HSNPYLQNGSNKTSQIHKR-----NSHNIELD--LGRPGIKSPQTRPAMCPQDNWLFTTC
GASGPHGPTQTQCNDAYRNVNLSVLLGAEEGFPGVQIWKVPATDTYSISTYGAAGGKG-K
NTIMRSNGVNVAGIFKLQKNESLYILVGQQGEDACPSANHIIQKVCLG------ENNVVE
EEIKANKSIYEWAGGGGGGGGATYIFKMENGKPVPLIIAAGGGGRAYRAKTYTFNFERLE
NDTSVPGLNGRP-GAAGGGGGWNDNTSFLWSGKSLLEGATGGKSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAENNDPE--M---DGEDGVSFLNIQYGTL-FTPALKVTE
GHGEVNIKLYVNCSHCAHDLCYRDVKTQEIVCTCLYGYVLAENGISCSAEM--VQPTKNP
PLSLVLSVVTSALVASLILAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKNIS

PF00069 // ENSGT00760000118818_8_Domain_6 (1237, 1501)

LIRGLGHGAFGEVYEGQVVGIPSD
PNPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSHPSSLVMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCK
GPGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--IHTVLPVEYGPCIE-----EEEKVPVRPEDPEAVPPLLVLPQQEK
RGAQQLLP---SPLSLALAIPPGKPLMKVAG-------IEQPPVRGNTQAPLEGGHVNMA
YAQSNS-ATELHKGGGSRNKPTNLWNPTYGSWFSEKPVVKNTSQVEKE--ATEG---EGS
GHEGNSTLGSSI--VTGRLPS----SSLLLEPSSLTASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAPA----PPLCQQLRGSSP-----------

MGA---IGLLWLLPLLLST------------AAVGSGMGTGQRAGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SSSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPGAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNHSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQDTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLRMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
-EEER-SPAAPPP--LPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVSYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------CL-PGTTP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEEGFCGWTPGTLSP-HTPQWQVRTLK-DALFQDQKGHALLLSTTDVPAAES
AT-VTSTTFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTINGEDKV
PQN----A-APKSRNLFER-----NPNKEPTPWEN------APRQTPIFDPTVHWLFTTC
GASGPYGPTQAQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGLFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNTASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---SEPHL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF00069 // ENSGT00760000118818_8_Domain_6 (1236, 1501)

TLLRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQQDPDV--INTALPVEYGPLIE-----EEEKVPMRPKDPEGIPPLLVSPQQAK
RGDEERRPAAP--PPPPAS-ASGKAGRKPP-TA-------EGSARGARAPAAEGGCVNMA
FSQSNP-PTELHKVHGSRNKPTSLWNPTYGSWFTEKPAKKNNPLA--KKEPQER---GSL
GREGGCTVPPSV-AATGRLPG----ASLLLEPSALTANMKDVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGTGHYEDTILKSKNSVTQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
LPSGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFEEGDCGWMPGSSAS-HPSPWRIGSAE-HKRFPSIEGCALLLNTSKAPAVAK
TV-MTSTAFPA-PLRNSPFCDLRMSWLIQGVLLGNVSLVLVENKTGKEQSWTFWHSEN--
--SKGLGIWQWMILPLPEILDRFWFQITASWEEGSDAIIAFDNVSLSLDCYLTSLCQKSL
CL-----GREPHSARLMQK-----PVSATSVA------LFELNTSKPLLQSEYQWLFTTC
GASGPYGPTQSQCNDAYRNSKLRVVVGAEGILQGIQIWRVPATNTYSISGYGAAGGKGGK
NTMVRSHGVSVLGIFDLQKDDTLYILVGQQGEDACPSTNDVIQKVCIG------ENNVIE
EEIRVNRSVNEWAGGGGGGGGATYIFKMENGEPIPLIIAAGGGGRAYRAKTDTFHPERLE
NDSSIPGLNGNS-GAAGGGGGWNDNTSFLWSGKSLLEGATGGRSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAVDNDPE--M---DGEDGVSFIN-PIGTL-YTPALKGIH
TGAQSSITRFASYSCAAVRAGHPRVKSMVILFFCLDYMHLGDDILQSSSCFC-SEPVVRL
PFSLVLSVVTSALVAALILAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKNIS

PF00069 // ENSGT00760000118818_8_Domain_6 (1237, 1501)

LIRGLGHGAFGEVYEGQVTGIPSD
PTPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLSMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCR
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPSAE-----EEEKVAMRPDDPEGIPPLLVSTHQDR
KDEKQTLP---SPPPLPSAVTAGKSLGKVGA-------LE-QPAPGKVSSATAGGHINMA
YAQSNP-PSELHKSRGSRNKPTNLWNPTYGSWFAEKQASKNSSLLEKE--RSER---ENL
GQEGNCTVGPNI--VTGRLPG----SSLLLEPSSLTASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLENST----PP---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------CA-PGSSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CDFEDGFCGWTQSSPSP-HTTQWQVRTLK-DARFQDHQGHALLLSITDAPTSEN
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLQGNVSLMLVENKTGKEQSRMIWRVAT--
--LEGLSLWQWTVLPLLEVADRFWLQIVAWWGQGSRATVAFDNISVSLDCYLTISGEDKI
PQN----T-APKSRNLFER-----NLNNELKPWVN------PSKETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRVNKSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWSDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIN-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKIICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF00069 // ENSGT00760000118818_8_Domain_6 (1236, 1501)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLVMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTRP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPMRPQDPEGIPPLLVSAAQAK
REEGR---EPAAPAALPSA-PPGKAGKKPAVAEA-------CVRGGARPPAVEGGHVNMA
FSQSNP-PSELPQVQGSRNKPTSLWNPTYGSWFTEKPTKKNTPPA--KKEQRER---GPP
GGEGA--RAVPAPAPAARHPG----ASLLLEPSALTASLRDVPLFRLRHFPCGTVNYGYQ
QQGFPPEAAP----GPGRYEDP--APKS-----QPAP

---MGAFGFLWLLPPLLLA------------AASYSGAATDQRSGSPASGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PPSPSEPEAGGLEARGSLALDCDPLLR
LLGPLPGISWPEGASSPSPEAGPTLSRVLKGGSVRKLRRAKQLVLELGEETILEGCIGPP
EEAAAVGILQFNLSELFSWWILHGEGRLRIRLMPEKKASEVGREGRLSSAIRASQPRLLF
QIFGT--GHSSLESPSEMPSSPGN-------FIWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRHVPSEEASRMNLL-DGPEAERSQEMPRGSFLLLN
TSADSKHTILSPWMRSSSDHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLAPTPGKHGWTVLQGRVGRPANPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENGFCGWTQSPLSP-HIPRWQVRTLR-DAHSQGHQGRALLLSTTDIPASEG
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRTVWHVAT--
--DEGLSLWQRTVLSLLNVTDRFWLQIVTWWGPGSRATVGFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEEKM
PLN----S-VPKSRNLFEK-----NPNKEPKSWQN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTEMFHPERLE
SNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCEHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
HEETS---AAPQPAALTA---PGPLVKKPPGAGAGA--GAGAGAGPVPRGAADRGHVNMA
FSQPNLP-PELHKGPGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP------GAE---PQ-
ARAGAAEGGWTGPGAGPRRAE----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATV-----AP----GDTMLKSKNKITQPGP

---MGAAGFLWLLPPLLLA------------AASYSGAATDQRAGSPASGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PRSPSEPEAGGLEARGSLALDCEPLLR
LLGPLPGISWADGASSPSPEAGPTLSRVLKGGSVRKLRRAKQLVLELGEETILEGCIGPP
EEVAAVGILQFNLSELFSWWILHGEGRLRIRLMPEKKASEVGREGRLSSAIRASQPRLLF
QIFGT--GHSSMESPSETPSPPGT-------FMWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRHVPSEEASRMNLL-DGPEAEHSQEMPRGSFLLLN
TSADSKHTILSPWMRSSSDHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLQGRVGRPANPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENGFCGWTQSPLSP-HMPRWQVRTLR-DAHSQGHQGRALLLSTTDILASEG
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRTVWHVAT--
--DEGLSLWQHTVLSLLDVTDRFWLQIVTWWGPGSRATVGFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEEKM
SLN----S-VPKSRNLFEK-----NPNKESKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTETFHPERLE
SNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
HEEAS---AAPQPAALTA---PGPSVKKPPGAGAGA--GAGAGAGPVPRGAADRGHVNMA
FSQPNPP-PELHKGPGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP------GAE---PQ-
ARAGAAEGGWTGPGAGPRRAE----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA-----AP----GDTMLKSKNKVTQPGP

MGT---IGLLWLLPLLLST------------AALGSGTGTGQRTGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDAPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDAFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPSYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------FGEYYLWPLDQKWTLTFTNQPSFLFLA------------
-----------------------------------------GQEGSKV-------YM-LH
SGSPPSAPPGVPVNPEPRGHCRST----------------TLSAGEACFS-------SLF
LCPFPPLISNAPSWTVLHGRVGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFACWNGTVVQLG------------------QACDFHRDCAQGEDEGQLCNQ
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HAPQWQVGTLK-DARSWDHQDHALLLSTTDVPSPES
AT-VTSATFPA-PIKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHEAT--
--NEGLSLWQRTVLPLLNVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKV
PQT----E-EPKSRNLFER-----NISKEPKSWEN------IPRQTPIFDPTVHWLFTTC
GASGPHGPTQTQCHNAYQNSNLSVTVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISCYGAAGGKGGK
NTMIRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQRVCIG------ESNVIE
EEIRVNRSVREWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWDDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGVL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHLDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKVRAAK-SLTFSVKFGCTPLPRSKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPPVE-----EEEKVPVRPEDPEGMPPLLLSPGQRV
-------PVPAVPPPAPAS-SSGKAVRKPAA---------------TRGPAAGGGHVNMA
FSQANP-PPELRRIQGSRNKPTSLWNPTYGSWFTEKPAKKNSAPA--KKEPHQR---GGL
GSEGSCTVPAAS-SAAGRLPG----ASLLLEPSSLPASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEVTT----APGDAI-----LKNKSNASQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MQMELQSPEYKLSKLCTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPMRPQDPEGIPPLLVSPPQAK
R-EEGQDPAAP--PPLPST-SSGKASKKPT-AA-------ELSVRVTRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPA--KKEHHER---GNL
GREGSCTVPPNV--ATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGTSHYEDTILKNQP-----GP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MPTPPDYFL------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLH

PF00629 // ENSGT00760000118818_8_Domain_0 (314, 473)

DLG---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEYCTLAVSVHRHLQPSGRYIAQLLPHNEA-GR-------EIL
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSQ
LPASFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTEGTFSP-HVPRWQVRTLK-DAWSQDHQDHALSLSTTDVPGPES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMIWHVAT--
--NEGLSLWQWAVLPLLNVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTIGGEDKM
PQS----E-EPKSRNLFER-----NTNKEPKSLDS------RPRHLPVFNPTVHWLFTTC
GASGPHGPTQTQCNNAYQNSNLSVIVGSEGPLKGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISCYGAAGGKGGK
NTMIRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ESNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHSERLE
NNSLVLGLNGNS-GAAGGGGGWDDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--I---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHLDPQSHKIICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYSFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMTG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPPME-----EEEKVPVRPKDPEGMPPLLVSPQQAK
PEVER-VPAPAVPLALPTA-ASSGKAVKKPAA--------GVSVQVPRGPAVEGGHINMA
FSQSNP-PPALHRVQGSRNKPTNLWNPTYGSWFTEKPAKKNNPPA--NKEPHQK---GSA
GREGSCTVPP-S-AAAGRLPG----ASLLLEPSSLTASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGAGHYEDTTLKNKSSAGQPGP

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------M---DGEDGVSFIN-PIGTL-YTPALKVTE
GHGEVDIRLHLNCSHCEMDECRVDLETQKVICFCEPGTDLAEDGVSCIA-----EPTVHL
PLSLVLSVVTSALVAALILAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1485)

SLIRGLGHGAFGEVYEGQVAGIPSD
PTPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQLSSLSMLDLLHVAHDIACGCQYLEENHFIHRDIAARNCLLTCR
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMDPPKNCPGPVYEILTSMYSCK-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

---MGALGLLWLLPLLLLA------------AASDSGAATDQRAGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PPSPSEPGASGLEARGSLALDCAPLLR
LLGPPPGVSWTEGASSPSPAVGSTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
EEATAVGILQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSTAIRASQPRLLF
QIFGI--GHNSLESPSVMPSPPDN-------FVWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRRVPSEEASQMDLL-NGPEAERSKGTPRGSFLLLN
ASADSKHAILSPWMRSNSEHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLHGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCS-
--------------------------------------------

PF00629 // ENSGT00760000118818_8_Domain_2 (585, 710)

-HVLLLSTTDAPTSKS
AT-VTSVTFPA-PMKNSP-CELRMSWLIHGVLKGNVSLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQWTVLSLLDVTDRFWLQIVTWWGPGSGATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PSN----E-APKSRNLFEK-----NPNKEPKSWAN------ISGSTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
HEEAP---AGPQPAALAA---PGPLVKKPPGAGTGA----GAGAGRLPRGAADRGHVNMA
FSQPNPA-PELHKSAGSRNKPTSLWNPTYGSWFTEKPAKKTHPP------QGAE---PQ-
ARAGAAEGGWTGPGAGPRRPG----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAT-----AAP----GDTVLKSK--VTQPGP

---MEARRLLWRLLLLA---------------ALGTSMGTGQRAGSLPGGPALQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPPP-PPVRSEVKASRPEARGSLA-DCVPLLG
LLAPPGF--------SASPAPARTLSRVLKGXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX---XXXX
XX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLECSF-
DFPCELEYSPPLHNLR---NQTWSWRRVSSEEASQIDLL-DGPEAEHSKEMPRGSFLLFN
TSANSKHTILSPWMRSSSEHCRLAVSVHRHLQPTGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVNFFALKNCS-EGTSP
GSKMALQSSFTCRNGTVLQLG------------------QACNFHQDCAQGEDEXXXXXN
LPDGFY

PF00629 // ENSGT00760000118818_8_Domain_3 (547, 620)

CNFENGFCGWMQGPLSP-PIPRWQVRTLK-DARFQNHPGHVLLLNTNDVPTFKR
AT-VTSVTFPA-PMRNSP-CEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX----X-XXXXXXXXXX-----XXXXXXXXXXX------XXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSXXXXXXXXXXXXXXXXXXXXX--
----XXXXXXXXXXXXXXXXXXXXXXXMKDGVPVPLIIAAGGGGRAYGAKTDTFHQERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASSNDPE--M---DGEDGVSFIS-PLGVL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHLDPESHKVICFCDHGTVLAEDGVSCVXXXX---XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX

PF07714 // ENSGT00760000118818_8_Domain_6 (1284, 1503)

XXXXXXXXKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPMRPKDPEGITPLLVAPPQGK
QGEVQG---SAAQAPLQAT-SSGKAPKKPAA---------GSSVRVPRGPAVDGGHVNMA
FSQSNP-PSELHKAQGSRNKPTSLWNPTYGSWFTEKPAKKNNPPV--KKEQLER---GSS
GREGNDPVPPSV--ATGRLTG----ASLLLEPSSLTANMKEVPLFRLRHFPCGTVNYGYQ
QQGLPLETAMVPGSGPGSGPYEDAMLKLQ-----PGP

------------------------------------------------------------
------------------------------------------------------------
----------------STPAPARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGTP
E-EEAAGLLQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIIGT--GRSSLESPTNMPSPPPDSSA------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDHG---NHSWSWRRVPSEEASQMDLL-DGPEAERANEMPRXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX------------XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXWTVLQGRVGRPENPFRVALEYISSGNRSLSAVDFFALKNCSEXXXXX
XXXXXXXXXXXXXXXXXX-XX------------------XXXX-XXXXXXXXXXXXXXXX
KLPAFYCNXXXXXXXXXXXXXXX-XXXXXXXXXXX-XXXXXXXXX

PF00629 // ENSGT00760000118818_8_Domain_2 (586, 670)

HALWLSTTDAPTSES
AT-LTSATFPA-PMKNSP-CELRMSWLISGDLRGNLSLVLVENKTGKEQSRMVWHVAT--
--NEGLSLWQWTVLPLLNVSDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX----------XXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGVQIWRVPATDTYXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXX
XXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXGGGGWNDNTSLLWSGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIXXXXXXXXXXX--X---XXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX

PF00069 // ENSGT00760000118818_8_Domain_6 (1275, 1503)

XXXXXXXXXXXXXXXXXKFNHQNIVRCIGVSLQALPRFILLELMTG
GDLKSFLRET-RPRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--IHTALPVEYGPPVEYGPPLEEEKVPVRPEDPERAPPLLVSPQQGK
REEARA---PAAPAPLPAA-ASDKAGKKPPAAA-------ERSARGPGGPALEGGHVNLA
FSQAHP-PPELRRAQGSRNKPTSLWNPTYGSWFTEKPAKKNSPLA--KKEPPER---GRA
GREGSCTVPP----------G----ASLLLEPSSLTASMKGVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAA----APGTGHYDAALLKTKRSGSQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------MSLKLVEERKYETIQVIS----ICHMK
LFVCCMCIHLYIHKHNFMSIRIYVYTHIGVE----KYTL-DVPDRCKNVHL---AYSLF-
--SDGVSVLDCRWMQSSPFD--------------------LLPSSSVCTFLQSLLILITV
FLCFSPLLSYASSWTVLHGRIGRPEHPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSQ
LPASFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CHFEDGFCGWTQGTFSP-DVPRWQVRTLK-DAWSQDHQDHALLLSTTEIPGPES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGALRGNVSLVLVENKTGKEQSRMVWHVAT--
--NKDLSLWQWTVLPLLNVSDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTISGEDKL
LQG----E-EPKSRNLYDR-----PPDKEP-PSEI------VPRQTATFDPTVHWLFTTC
GASGPHGPTQTQCNNAYQNSNLSVMVGSEGPLKGVQIWKVPATDTYRCPYAGAGT-----
----------QVGRSFLSKDDVLYILVGQQGEDRLPSTNHLIQKVCVG------ESNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWDDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGILLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPPVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
QE-EARIPAPALPPPLSTV-ASSDKAVKKPTAA-------GVSVQGPRGPATAGGHVNMA
FAQSNP-PPELRRVQGSRNKPTSLWNPTYGSWFTEKPAKKNNPPP--KKEPQPR---GST
GRAESCTVPPNATTSTGRLPG----ASLLLEPSSLTASMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGAGHYEDTILKNKSNTGQPGP

MGT---TWLLWLLPLLLSA------------AALGSRTPTEQRAGSQAVGAPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPP----SPSEPRAGRLEARGSLALDCAPLVR
LLGPPAASS-----L--SPAADPTLSRVLKGGSIRKLRRAKQLVLELGEEAILEGCVGPP
E-EAAVGLLQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGI--GHSSLESPTNMPSSPPDHFV------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLH

PF00629 // ENSGT00760000118818_8_Domain_0 (314, 473)

DLG---NQSWSWRRVSPEEASQVDLM-DGPEAEFSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNEA-GR-------EIL
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHHDCAQGEDEGHLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEHGFCGWTQGTPSP-HVPQWQVRTLK-DARSQDQPGHALSLSTTDVSTSES
AT-VTSATFPA-PIKNSP-CELRMSWLIRGVLRGNVSLMLVENKTGKEQSRMIWHVAT--
--NEGWSLWRWTVLPLLDVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----A-EPKSRNLFER-----NPNKDQKTLKN------TSEQPPTFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNQSVVVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSANQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWKDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

SLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPMRPKDPEGMPPLLVSPQQAK
RGEDR-APAAPPA--LPAP-SSGKAVKKPGAA--------EASARVPRGPAAEGGHVNMA
FSQSNP-PAELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPA--KRESQER---GR-
-----CTVPAGG-AAPGRLAG----ASLLLEPSSLTATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGASHYEDSVLQTKNKANHPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------CS-PGTSL
GSKMALQSSFTCWNGTVLQLG------------------QACDFHLDCTQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQSTLSP-NTPRWQVRTLR-DGQSQDHQGRALWLSTTDAPTSAS
AT-LTSATFPM-PMKNSP-CELRMSWLIRGVLRGNISLVLVENKTGKEQSRMVWHVAT--
--DEGLSLWQWTVLPLLNVTDRFWLQIVAWWGEGSRATVAFDNISVSLDCYLTISGEDTV
PQN----A-APKSRNLFDR-----NPNKEPKPWES------TPRETPIFDPTVHWLFTTC
GASGPQGPTQAQCNNAYRNSNLSVVVGSEGPLKGVQIWRVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFPLEKDDILYILVGQQGEDACPSANQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKGGVPVPLIIAAGGGGRAYGAKTDTLHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--V---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHRVICFCDHGTVLAEDGVSCIVSPT---REPRL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTVM
TDYNPNYCFAGKT--------SSISDLKEVPRKHI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPMRPKDPEGVPPLLVSPQPAQ
REEAP---APAAPAPVPAP-ASARAVKKPAAQVS---------ARVLRGPAVGGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPAKKTNPPA--KKEHGER---GGA
GRQGA--CTVPPGAATGRLPG----ASLLLEPSSLPASVKGVPLFRLRHFPCGNVNYGYQ
QQGLPAEASA----APGTSPYDEAILKKKSRASQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------LHGRIGRLENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSQ
FPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWMQGTLSP-HVPWWQVRTLK-DARSQDHQDHALSLSTTDVPGPES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENRTGKEQSRTVWHQAA--
--SEGLSLWQRAVLPLFNVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
PQT----E-EPKSRNLFER-----DTNKEPKSWEN------IPRQTPIFDPTVHWLFTTC
GASGPQGPTQTQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1061)

TDTYSISCYGAAGGKGGK
NTMTRSHGVSVLGTFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCVG------ESTVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGLGTHGEQAD---------------------KRQEGV

ENSGT00760000118818_8_Linker_5_6 (1061, 1236)

AWGC-GPRLRPTPSLLLVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGISCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
SDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPPVE-----EEEKVPMRPKDPEGMPPLLVSPQPSK
GQEER-VPQQGLPLEAAAP-GAGHCEDAVLK---------------SKGSASQPGP----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

---MGALGSPWLLLLLQSLV----------ASASGSGTRTSQRTGSLAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPP----FPSERRAGRPEARGSLALDCAPLLR
LLGPPAGVSWSAEAGS--PAPARALSRVLKGGSVRKLRRAKQLVLELGEEAVLEGCVGPP
G-EAVAGLLQFNLSELFSWWILHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QILGT--GPSSLESPTSXXXXXXXXXXX------XXXXXXXXXXXXXXXXXXXXLKCSF-
DFPCELEYSPPLHDPR---NHSWSWRRVPSEEASRLDLL-NGPEAERSKEMPRGSFLLLN
TSANSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPSPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSA
GSKMALQSSFTCWNGTVLRLG------------------QACDFHQDCAQGEDEGQLCGR
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CDFQDDFCGWTPSTLSP-YTPQWQIRTLK-DAEGYQXXXXXXXXXXXXXXXXX-
---XXXXXXXXXXXXXXX-XXLRMSWLIRGVLKGNISLVLVENKTGKEQSRLVWHGAA--
--NEGLDLWQCILLPLLDVSDRFWLQILAWWGKGTRATVAFDNISISLDCYLTISGEDKN
A--------APKSRNLFER-----NPNKELTPWRN------PPRETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRHSNLSVVVGSHGPLKGIQIWKVPATDTYXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTSQLIQKVCVG------ENNVIE
EELRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHAERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSQLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIXXXXXXXXXXX--X---XXXXXXX-XX-XXXXXXXXXXXXXME
GHGEVNIKHYLNCSHCEIDECHLDPESHKVICFCDHGTVLAEDGVSCIXXXX---XXXXX
XXSLILSVVTSALVAALILAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF00069 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGMPND
PGPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDIAARNCLLTCP
GAGRVAKIGDFGMARDIYRASYYRKGGCAMLPXXXXXXXXXXXXXXXXXXXXXSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

MGSLELVGLLLLLLLSVAASGSGTGIETETGTGTGTGTGTGQLVGSPAMGPALQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPLS----SWSESRAGRTEARGSLALDCAPLLR
LVGPPPTVSWTEGPSSAAPAPARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
-EEVTAGLLQFNLSELFSWWIHHGEGRLRIRLMPEKKSSEVGREGRLSAAIRASQPRLLF
QILGT--GHSSLESPTSLSSPPPDPFA------WNLTWIMKDSFPFLSHRSRYGLECSF-
NFPCELEYSPPLHDLG---

PF00629 // ENSGT00760000118818_8_Domain_0 (320, 474)

NQSWSWRRVPSEEASQMDLL-DGPDTEHSKEMPRGSFLLLN
TSANSKHTILSPWMRSSSEHCRLAVSVHRHLQPSGRYVAQLLPHNEP-GR-------EIL
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSS-HNPRWQVRTLK-DARDQDHGGHALLLSTTDSPTYES
AT-VTSVTFPA-PMKNSP-CELRMSWLIRGVLQGNVSLVLVENKTGKEQSRMVWHVAT--
--NEGLSLWQWTVLPLLDVTDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTISGEDKM
PQN----T-APKSRNLFER-----NPSKEPKAWEN------T-RETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGTL-YTPALKVME
GHGEVNIKHYLNCSHCEGDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGAPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPMRPQDPEDMPPLLVSPPPAK
R-EEGQDPAGP--PPRPST-SSGKAVKKPA-AA-------ELSVQVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPA--KEELRER---AHL
GREGGCTVPPNV--AAGRLPG----ASLLLEPSSLTASMQDVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA----APGAAHYEDALLKSQP-----GP

MGA---IGLLWLLLPLLSV------------AASSSGTRTGQRVDLPAIGPVLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARELLLPPPSL----------SPEARGSLALDCAPLLR
LVGPPPGVSWTAGAS--SPAPAQTLSRVLKGGSIRKLRRAKQLVLELGEEAILEGCIGPP
E-EATAGLLQFNLTELFSWWIHHGEGRLRIRLMPEKKPSEVGREGRLSAAIRASQPRLLF
QIFGS--GHSSLESPTDLPSLPPDSFA------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDLG---NQSWSWRRVPSEEASKMDLL-DGPEAEHSKEIPRGSFLLLN
TSANSKHTILSPWMRSSSEHCRLAVSVHRHLQPSGKYVAHLLPHNEA-GR-------EIL
LVP----TPGKHGWTVLEGKIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSL
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CNFEDGFCGWTQGTLSP-HTPRWQVKTLK-EARFQDHQGQALLLSTTEVPTSKS
AT-VTSATFPA-PMKNSP-CELRMSWLVRGVLRGNISLVLVENKTGKEQSRMVWHVAT--
--SEGLSLWQWTVLPLLDVADRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEDKM
PQN----T-APKSRNLFER-----SPNKEVKLCEN------TPRETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGR
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRMNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGLSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALILAFSGIMI--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--------XXXSDLKEVPRGN

PF00069 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLLRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLME-----EEEKVPMRPKCPEGIPPLLVSPPPTK
RETGP-DPAAPPPP--PSA-PSGKAVKKA-TAA-------EVPVRVTRGPAVEGGHINMA
FAQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPA--KKGQHDR---GNV
GREGSCIVPP-N-IATGILPR----DSLLLEPSSLT------------------------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------F
LCLCP--GHSSLESPSEMPSPPGN-------FLWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHTHG---NQSWSWRRVPSEEASRMNLL-DGPEAEHLKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLHGRVGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQNCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQSPLSP-RVPRWQVKTLK-DTHSQGHQGHALLLSTTDDPTSES
AT-VTSATFPA-PMKSSP-CELRMSWLIRGVLKGNVSLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQWTVLSLLDVTDRFWLQIVTWWGPGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEEKM
SLN----A-VPKSRNLFEK-----NPNKEPKPWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTETFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQSAK
HEEAS---SAPQPSALAA---PGPLVKKPSGAG------AGAGAGPVPRGAADRGHVNMA
FSQPNPP-PELHKGPGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP------GAE---PQ-
ARAGAAEGGWTGPGAGPRRAE----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA-----AP----GDTVLKSKTKVTQPGP

MRA---IGLLWLLPPLLSA------------AASSSGAAVGQRAGSPAVGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPPSPPPSPPEPRAGQAEEHGSLALDCAPLLR
LLGPPPGVSW--------APASPTLSRVLKGGSVRKLRRAKQLVLELSEEAILEGCLGPP
E-EAAAGLLQFNLSELFSWWIRHGEGRLRVRLMPEKKASEGGREGRLLQGVQLQPVESTW
QFLCP--GPSSLESPTNRPSPPPDYFS------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDLR---

PF00629 // ENSGT00760000118818_8_Domain_0 (320, 474)

NQSWSWRRVPSEEASQMDFL-DGPEAERSKERPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNKT-GR-------EIL
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------RACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGLCGWTQGVLSS-RVPRWQVRTLK-DAWSQDHQGHALLLSTTDAPSSES
AT-MTSVTFPA-PMKNSP-CELRMAWLIRGVLRGNVSLVLVENKTGREQSRILWHGAP--
--GDGLSLWQWAVLPLLDVSDRFWLQMVAWWEQGSRATVAFDNISISLDCYLTISGEDKT
LQS----T-EPRSRNLFDG-----SPNKESKPREA------TPR-TPTFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNQSVVVGSEGPLKGIQIWTVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGISFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPETHKVICFCDHGTVLAQDGVSCVVSPT---AEPHL
PLSLILSVVTSALVAALVLAFSGIMV--VYRRKHQELQAMQMELQSPEYKLSKLRTATIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFPRGDPALRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GTGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPMRPKDPEGVPPLLVAPAQAK
REEA---PVAAAPAALPAA-SSGKAVKKPEAAA-------QAPARARRGPAVGGGHVNVA
FAQSNP-PSEMHKDQGSRNKPTSLWNPTYGSWITENPARKNMP-----------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------GLSSQFGEYYLWPLDQKWTLTFTNQPSFLFLA------------
-----------------------------------------GQEGSKV-------YM-LH
SGSPPSAPPGVPVNPEPRGHCRST----------------TLSAGEACFS-------SLF
LCPFPPLISNAPSWTVLHGRVGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFACWNGTVVQLG------------------QACDFHRDCAQGEDEGQLCNQ
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HAPQWQVGTLK-DARSWDHQDHALLLSTTDVPSPES
AT-VTSATFPA-PIKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHEAT--
--NEGLSLWQRTVLPLLNVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKV
PQT----E-EPKSRNLFER-----NISKEPKSWEN------IPRQTPIFDPTVHWLFTTC
GASGPHGPTQTQCHNAYQNSNLSVTVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISCYGAAGGKGGK
NTMIRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQRVCIG------ESNVIE
EEIRVNRSVREWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWDDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGVL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHLDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKVRAAK-SLTFSVKFGCTPLPRSKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPPVE-----EEEKVPVRPEDPEGMPPLLLSPGQRV
-------PVPAVPPPAPAS-SSGKAVRKPAA---------------TRGPAAGGGHVNMA
FSQANP-PPELRRIQGSRNKPTSLWNPTYGSWFTEKPAKKNSAPA--KKEPHQR---GGL
GSEGSCTVPAAS-SAAGRLPG----ASLLLEPSSLPASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEVTT----APGDAI-----LKNKSNASQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MVLEKTL-
ESPLDCKEIQPVHSEG---DQPWDFFGRNDGSTSLYGMENMGPEVR--------------
--------------AGMGPLCGIGLLLITV----------FL------------------
--CFSPLPSNATSWTVLQGRIGRPENPFRVALEYISNGNRSLSAVDFFALKNCS-EGSSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CDFEDGFCGWTQTSPSP-HMPQWQVRTLK-DAQFQDHQGHALLLSITDAPTSEN
AT-VTSTTFPA-PMKNSP-CELRMSWLIRGVLQGNVSLMLVENKTGKEQSRMIWHVAT--
--LEGLSLWQWTVLPLLEVADRFWLQIVAWWGQGSRAVVAFDNISVSLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PQN----T-APKSRNLFER-----NLNNELKPWVN------PSKETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1064)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSANRLIQKVCIG------ENNVIE
EEIRVNKSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWSDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFI

ENSGT00760000118818_8_Linker_5_6 (1064, 1236)

N-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKIICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKSI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLVMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPMRPQDPEGIPPLLVSAAQAK
REEGR---EPAAPAALPSA-PPGKAGKKPAAAEA-------CVRGGARPPAVDGGHVNMA
FSQSNP-PSELPQVQGSRNKPTSLWNPTYGSWFTEKPTKKNTPPA--KKEQRER---GPP
GGEGA--RAVPAPAPAARRPG----ASLLLEPSALTASLRDVPLFRLRHFPCGTVNYGYQ
QQGFPPEAAP----GPGRYEDP--APKS-----QPAP

MGA---IGLLWLLPLLLST------------AALGPGTGAGQRLGSPAAGLQLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPPPGVSWTTGSP--AQAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAAGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGI--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHHSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDFL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDSPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQIRTLK-DARLQDHQDYALLLSTTDVPTSES
AT-VTSATFPA-PMKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PQK----T-APKSRNLFER-----NPNKELKPGEN------SARQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGMPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGVNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTTLPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSHQVKR
GEEER-GPAAPPP--LPTT-SSGKATKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------S-LGAAS
VSKMALEGSFSCWNGTSISLG------------------QTCDFIRDCTEGEDEGAMCRE
LPSGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CSFEEGDCGWMEGSSAS-RASPWRIGSVE-YNRFPSVEDYALILDTSKAPAGAS
TV-MTSATFPT-PLRNSP-CELRMSWLIRGVLLGNISLVLVENKTGKELSRTFWHSAN--
--SEGLGIWQWLILPLPDILDRFWFQIIASWERGSNAIIAFDNVSLSLDCFLTINGE-KI
PR-----STTPDSSNLLTS-----RRGPNNFGWEQKLLGNLQLGTAPISGPADHWLFTTC
GASGAYGPTQSQCNDAYRNSNLSVIVGAEGILQGIQIWRVPATNTYSISGYGAAGGKGGK
NTMVRSHGVSVLGIFDLQKDDTLYILVGQQGEDACPSTNDVIQKVCIG------ENNVIE
EEIRVNRSVNEWAGGGGGGGGATYIFKMENGEPVPLIIAAGGGGRAYRAKTDTFHPERLE
NDSSVPGLNGNS-GAAGGGGGWNDNTSFLWSGKSLLEGATGGRSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAEDNDPE--M---DGEDGVSFIN-PIGTL-YTPALKVTE
GHGEVDIRLHLNCSHCEMDECRVDLETQKVICFCEPGTDLAEDGVSCIA-----EPTVHL
PLSLVLSVVTSALVAALILAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ISLIRGLGHGAFGEVYEGQVAGIPSD
PTPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQLSSLSMLDLLHVAHDIACGCQYLEENHFIHRDIAARNCLLTCR
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPSVE-----EEEKVAIRPEDPEGIPPLLVSSHQDR
KDDKQTLP---SPPPLPSAITAGKALGKAGS-------LE-SSVPGKVQAASGGGHINMA
YAQSNP-PSELHKGRGSRNKPTNLWNPTYGSWFAEKQASKNKPLLEKE--MPER---ENL
GHEGNCTVGPNI--VTGRLPG----SSLLLEPSSLTASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAST----PPCASSYEDPTLRNKSHISQQGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MG---GQCF---------LKKFMQNWRQNTIDRKTYNISVIF-
GEKCLIQS-HQANEGQ---SQNWNWRSLQGRDPVHMLRL-----------------IL--
-----------------------------------------IT-----VS-------LCF
SPL----LSNATSWTVLQGRIGRPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVSTLK-DARFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVTA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGGRQ-EGF
RRGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--LPTT-SSSKAAKKPIAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA---KEPHEK---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------PNATSWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALRNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------HACDFHRDCAQGEDEGPLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDDFCGWTQSILSP-HMPQWQVRNLK-NAQSQGRQGHALLLSTTDVPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHVATND
ASNEGLSLWQWTVLSLLDVSDRFWLQIVVWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
PLN----A-APKSRNLFER-----NSHKDSKA--N------VSGTTPIFDPTVHWLFTTC
GASGPYGPTQAQCNNAYQNSNLSVVVGNEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATFVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGTPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCA
GTGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPPAKH
EDAPA-APQQQSAQAAP----AKAVKKAPAAG--------AGSSRVPRGPAAEGGHVNMA
FAQSNP-PAELHKAPGSRNKPTSLWNPTYGSWFAEKPAKKHAPRAAA--EPQGR---AGA
GCEGGWTRPG---VPGPRGAG----AALLLEPSALTASMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA------GAGHLEDSVLKNKSSATQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------CA-PGSSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCRK
LPDGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CDFEDGFCGWTQTSPSP-HTPQWQVQTLK-DAQFQDHQGHALLLSITDAPTSEN
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLQGNVSLMLVENKTGKEQSRMIWRVAT--
--LEGLSLWQRTVLPLLEVADRFWLQIVAWWRQGSRAVVAFDNISVSLDCYLTISREDKI
PQN----T-APKSRNLFER-----NLNSELKPWVN------PSKETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSANRLIQKVCIG------ENNVIE
EEIRVNKSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWSDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGG-
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIN-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKIICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKSI

PF00069 // ENSGT00760000118818_8_Domain_6 (1236, 1501)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLVMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLVE-----EEEKVPMRPQDPEGIPPLLVSGAQAK
REEGR-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

---MGALGLLWLLSLLLLA------------AASDSGAATDQRSGFLAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PPSPSEPGASGLEARGSLALDCAPLLR
LLGPPPGVSWADAASSPSPEVGSTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCIGPP
EEATAVGILQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSTAIRASQPRLLF
QIFGT--GRSSLESPSGMPSPPDN-------FVWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRRVPSEEASQMDLL-NGPEAERSKGTPRGSFLLLN
ASADSKHAILSPWMRSNSEHCTLAVSVHRHLQPSGRYIAQLLPHNEAGRE----------
--ILLVPTPGKHGWTILHGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGPLLP-HLPRWQVRTLK-DAHSRDQQGHVLLLSTTDVPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIHGVLNGNVSLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQWTVLSLLDVTDRFWLQIVTWWGPGSGATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
PSN----A-APKSRNLFEK-----NPNKDPKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKALLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
HEEVP---AAPQPAALVA---PGPLVKKPPGAGAGAG--AGAGAGRAPRGAG--------
------------------------------------------------------------
----------------------------------------------------GNVNYGDQ
QQGLPMEAT-----AAP----GDTVLKSKNKVTQPGP

MGT---IGLLWLLPLLLST------------AALGSGTGTGQRTGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQNHQDHALLLSTTDAPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDAFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

MGT---IGLLWLLPLLLST------------AALGSGTGTGQRTGSPAEGLPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPTEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSTSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICWK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVSTLK-DARFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQIVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQASSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPKFAIIL
ERIEYCTQ----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MLLASTAEGSGWVVLRGRIGRPEKPFRISLDYISSENRSLSAVDSFALKNCS-EGMSP
GSKMALQSFFTCWNGTVIALG------------------QACDLRRDCVHGEDEGELCRK
LPTGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFEEGGCGWTQDPPAP-HAPQWQIGKLD-GAQFSAQQGTVPQQTTDCISGSPG
MTPSSAPPFPGPPQENSA-TKVQMSWLIHGFLGGNVSLLLVENKTGKEQSRMVWHFAN--
--GEGLSTWQRMVLPLAEVSDRFWLQIVTWWEEGSDAVIAFDNVTLSLDCYLTIRGEDTT
PLD----S-TPNSSNLFNERNMYKKAVTETKTWET------AHGEVPISDPTAHWLFTTC
GASGPRGPTQTQCNNAYRNSNLTVEVGAEGSLKGVQIWRVPVTDTYRISGYGAAGGKGGK
NTMMRSYGVSVLGIFDLQKGDTLYILVGQQGEDACPHTNHVIQKVCIG------ESNVIE
EEIQVNRSVNEWAGGGGGGGGATYIFKILDGEPVPLIVAAGGGGRAYRAKTNPLHPERLE
NDSSVPGLNGHS-GAAGGGGGWNDKTSLLWSGKSLLEGATGGKSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGDAAMDNDPE--V---DGEDGVSYIS-PLGIL-YTPALKVME
GHGEVNIMQHLNCSHCEVDECHLDPETHKIICYCDHGTVLAEDGVSCVASPT---TSPHL
PLSLILSVVTSALVAALVLAFSGIMI--GFIQQHNQVLTGIRSCPSPQGRINESWLLTCL
SVYIPLYHGKPLI--------LPISQLRDASSSNSILF

PF00069 // ENSGT00760000118818_8_Domain_6 (1239, 1501)

RGLGHGAFGEVYEGQVSGIPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLGMLDLLNVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKSCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLIE-----EEEKVPMRPEDPEGIPPLLVSPQQEK
KEEGRAP---PAPPPLPTS-AASRKAMTRA-------AVAEPPPRVRKGPALEGGHVNMA
YSQSNP-PSELHKGRGSRNKPTSLWNPTYGSWFTEKPATKHNPPAEK-EQPPER---GSA
GHEGNCPVPPNV--VTGRLPG----SSLLLEPSSLTASLKDVPLFRLRHFPCGNVNYGYQ
QQGLPLEATS----GSGTGNYEDSLLRNKSSGSQPGP

---MGAVGFLWLLPPLLLA------------AASYSGAATDQRAGSPASGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PRSPSESEAGGLEARGSLALDCEPLLR
LLGPLPGISWAEGASSPSPEAGPTLSRVLKGGSVRKLRRAKQLVLELGEETILEGCIGPP
EEAAAVGILQFNLSELFSWWILHGEGRLRIRLMPEKKASEVGREGRLSSAIRASQPRLLF
QIFGT--GHSSLESPSETPSPPGT-------FMWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHR---NQSWSWRHVPSEEASRMNLL-DGPEAEHSQEMPRGSFLLLN
TSADSKHTILSPWMRSSSDHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLQGRVGRPANPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENGFCGWTQSPLSP-HMPRWQVRTLR-DAHSQGHQGRALLLSTTDILASEG
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNISLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQHTVLSLLDVTDRFWLQIVTWWGPGSRATVGFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEEKM
SLN----S-VPKSRNLFEK-----NPNKESKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTETFHPERLE
SNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAADGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
HEEAS---AAPQPAALTA---PGPSVKKPPGAGVGAGAGAGAGAGPVPRGAADRGHVNMA
FSQPNPP-PELHKGPGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP------GAE---PQ-
ARAGAAEGGWTGPGAGPRRAE----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA-----AP----GDTMLKSKNKVTQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------LPSPSWTVLHGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGASP
GSKMALQSSFTCWNGTALQLG------------------QACDFHQDCAQGEDEGQLCRQ
LPASFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFEDGFCGWTQGTFSP-HVPQWQVRTLK-DAWSQDNQDHALLLSTSDFPGPES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLMENKTGKEQSRMVWHVAT--
--NEGLSLWQWTVLPLLNVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PQS----E-EPKSRNLFER-----NTNKEPKPWEN------MPRQTPVFDPTVHWLFTTC
GASGPHGPTQTQCNNAYQNSNLSVMVGSEGPLKGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISCYGAAGGKGGK
NTMTRSHGVSVLGIFNLEKDDVLYILVGQQGEDACPSTNQLIQKVCIG------ESNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDMFHPERLE
NNSSVLGLNGNS-GAAGGGGGWDDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEIDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKVRGGFLSS---LALALGLSGDHDLQLKNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPPME-----EEEKVPMRPKDPEGMPPLLVSPQQAK
QEEER-VPGPALPPAPSSA-ASGKAVRKPTAAL-------GLSVQGPRGPATEGGHVNMA
FSQSNP-PPELHRVQGSRNKPTSLWNPTYGSWFAEKPAKKNNPAA--KKEPHQK---GT-
-GAQSCSVPP-N-AAASRLPG----ASLLLEPSSLTASMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGAGHYEDTVLKTKGNTGQPGP

---MGAVGFLWLLPPLLLA------------AASYSGAATDQRAGSPASGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PRSPSEPEAGGLEARGSLALDCEPLLR
LLGPLPGISWAEGASSPSPESGPTLSRVLKGGSVRKLRRAKQLVLELGEETILEGCIGPP
EEAAAVGILQFNLSELFSWWILHGEGRLRIRLMPEKKASEVGREGRLSSAIRASQPRLLF
QIFGT--GHSSLESPSETPSPPGS-------FMWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRHVPSEEASRMNLL-DGPEAERSQEMPRGSFLLLN
TSADSKHTILSPWMRSSSDHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLQGRVGRPANPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENGFCGWTQSPLSP-HVPRWQVRTLR-DAHSQGHQGRALLLSTTDIPASEG
VT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRTVWHVAT--
--NEGLSLWQRTVLSLLDVTDRFWLQIVTWWGPGSRATVGFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEEKM
SLN----S-VPKSRNLFEK-----NPNKESKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTETFHPERLE
SNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
QEEAS---AAPQPAALTA---PGPLVKKPPGAGAGA--GAGAGAGPVPRGAADRGHVNMA
FSQPNPL-PELHKGPGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP------GAE---PQ-
ARAGAAEGGWTGPGAGPRRAE----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA-----AP----GDTMLKSKNKVTQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------WLFTTC
GASGPQGPTQTQCNNAYRNSNLSVVVGSEGALKGVQIWRVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGVFDLEKDDFLYILVGQQGEDACPSTNEIIQKVCIG------ENNVIE
EEIRANQSVNEWAGGGGGGGGATYIFKMKNGIPVPLIIAAGGGGRAYGAKTDKFHPERLE
NNSSVLGLNGIS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGKDASRSRCQFPSFSHRGQHQDLMWFLIPLPVP-PAQALL---
GE-------EAPTSPCDSEHPSRRQRGPRAA--ALGGTAAHREKIL---SRTNWKDNSHL
SISLERQ--ASEM-----GSWKPVPA-VPIHKAQCQFKA-LLKSRLPI-FLLKIRCSFNK
TNAYRRICFCKTPGLPLQSFINLDVKISSLNSNRL

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

SLSRGLGHGAFGEVYEGQVSGIPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHLPEDRPNFGTIL
ERIEYCTQ-DPDV--VNTALPIEYGPVAE-----EEEKVPMRPEDPDRIPPLLVSPQQEK
KEDVCPSP---GPPPLPTTSS-GK------------------------------------
-------------PLKSRNKPTSLWNPTYGS-----------------------------
------------------------------------------------------------
-------------------------------------

---IGAMGLLWLLLPLLSA------------TAFGSGTGTGHRAGSPALGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPAP----SPSEPRAGRPEARGSLALDCAPLLR
LLGPQPGVSWTSGASSPAPTTARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCGSPE
--ESTSGLLQFNLSELFSWWIRHG-GRLRIRLMPEKKASEVGREERLSAAIRASQPRLLF
QIFWTD--HKFLETPADTPSPPPDSFV------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDPR---NQSWSWRRVPSEEASQMDLL-DGSEAERSKEMPRGSFLLLN
TSANSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPMPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTPP
GSKMALQSSFTCWDGTVLRLG------------------QACDFHRDCAQGEDEGHLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_4 (547, 620)

CNFENGFCGWTQDTLSP-HAPQWQIRTPK-DVQFQDHKGHALLLSTTDVPTFKS
AT-VTSATFPA-PMKNSP-CEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXX--X-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXX----XXXXXXXXXXXX-----XXXXXXXXXXX------XXXXXXXXXXXXHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPATNTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGQDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGLPVPLIIAAGGGGRAYGAKTETFHSEKLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIXXXXXXXXXXX--X---XXXXXXXXXX-XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF00069 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYXXXXXXXXXXXXXXXEWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLIE-----EEEKVPMRPKDPEGIPPLLVSPQQAK
REEERKA----APPPLPAP-CSGKAAKKPAVA--------EVSARVPAGLAAEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPASKDRPPARKEH-----------
RDRGGCPVPPSAAAAPGRLPG----TSLLLEPSSLTASVKEVPLFRLRHFPCGTVNYGYQ
QQGLPLEATA----APGTGLHEDSI-KTKSSVGHAGP

MGA---IGLLWLLPLLLST------------AALGSGMGVGQRLGSPAAGLQLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPPPGVSWTWGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAAGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDFL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCMLAVSVHRHLQPSGRYVAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDSPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFEDGFCGWTQGTLSP-HTPQWQVRTLK-DAQFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PQK----A-APKSRNLFER-----NPNKELKPGEN------SARQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWRVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSHQVKR
GEEER-GPAAPPP--LPTT-TFGKAAKKPTAA--------GVSVRVPRGPAMEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KEEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGAGHYEDTILKSKNSMNQPGS

MGT---IGLLWLLPLLLST------------AALGSRTGTGQRTGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDAPTLES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1237)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNIA

PF07714 // ENSGT00760000118818_8_Domain_6 (1237, 1502)

LIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KEEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

MGA---IGLLWLLPLLLST------------AAVGSGMGTGQRAGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SSSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRIPSEEASQMDLL-DGPGAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDVPASES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWMVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
-EEER-SPAAPPP--LPTT-SSGKAAKKPTAA--------EISVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIA--KKEPHDR---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

MGA---IGLLWLLPLLLST------------AAVGSGMGTGQRAGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SSSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDLR---

PF00629 // ENSGT00760000118818_8_Domain_0 (320, 474)

NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIP
LMP----TPGKHGWTVLQGRIGHPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCTQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDYQDRALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKI
PQN----T-APKSRNLFER-----NPNKELKPGET------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVASEGPLKGIQIWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPRTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKP
-EEER-SPAAPPP--LPTT-SSGKAAKKPTAA--------EVSVRLPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

MEAAVLLW---LLLPLLSTAAL------------GSGTGTGPRAGSPAVGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPS-----PSELRAGRPEARGSLALDCAPLLR
LLGP-PGVSGTAGSSPPAPAAARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
-EEPAVGLLQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPHLLF
QIFGT--GHSYLESPTNMPSPPPDYFV------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDLK---NQSWSWRHVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSERCTLAVSVHRHLQPSGRYVARLLPHNEA-GR-------EIV
LVP----TPGKH---------------------------------------------TTP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DAPFQDHQGRALLLSTTDVPAAES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGREQSRMVWQVAA--
--SEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
SQN----A-APKSRNLFER-----NPNKEPKPTEN------IPRQTHIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGLFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPEKLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGVL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHRVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLLRGLGHGAFGEVYEGQVSGMPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLLE-----EDEKVPMRPKDPEGIPPLLVSPQQAK
R-EEERGPAAP--PPPPPT-SSGKAVKKPT-VA-------EVSVRVPRGPAAEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEQHER---GNL
GREGSCTVPPSA--ATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGTSHYEDTILKSKNSVNQPGP

MGA---IGLLWLLPLLLST------------AAVGSGMGTGQRAGSPAAGPALQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SSSELKAGRPEARGSLALDCAPLIR
LLGPAPGVSWTAGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPGAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDVPASES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLRMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
PQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIGYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
-EEER-SSAAPPP--LPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---G--
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APAAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------WLFTTC
GASGPQGPTQTQCNDAYRNSNLSVIVGAEGILQGVQIWRVPATNTYSISGYGAAGGKGGK
NTMVRSHGVSVLGIFDLQKDDALYILVGHQGEDACPSTNHVIQKVCIG------ENNVIE
EEIRMNRSVHEWAGGGGGGGGATYIFKMENGEPVPLIIAAGGGGRAYRAKTDTFHPERLE
NDSSVPGLNGNS-GAAGGGGGWNDNTSFLWSGKSLLEGATGGKSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAADNDPE--I---DGEDGVSFIS-PLGTL-YTPALKVTE
GHGEVAIKLHLNCSHCELDECRVDLETQKVICFCEPGTDLAADGVSCVADP-----GAHL
PLPLVLSVIAFMS-----ASMTHCAPFVVYRRKHQELQAMQLELQSPEYKLSRLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

SLIRGLGHGAFGEVYEGQVVGILSD
PNSLQVAVKTLPEMCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLSMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCQ
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPIKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMNPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--VTTALPVEYGPSIE-----EQEKVPMPEK----------------
------------------------PLAKVAA-------PE-PPVP--ARPSLEGGHINMA
YAQSTP-ASELQKGRGSRNKPTNLWNPTYGSWFSEKPVDKNSSLLEKA--VSER---ENL
SGIQ--------------------------------------------------------
-------------------------------------

MGT---IGLLWLLPLLLST------------AALGSGTGTGQRTGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DAQFQDHQDHALLLSTTDAPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----TSLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------GNLS
GLKMALDGVFNCRNGMAIKLR------------------QVCNFIPDCEEEEDEGDLCRN
LPPGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CMFEEGSCGWALDHL----NSRWQVGSVGKSPEFQSHSGSVLYLNVSNSKSAAR
DV-LSSVLFPA-PLKNSS-CELRMSFLLKGFLLGNISVLLVDNKTGKVRTRPLWSFEN--
--GEGLGVWQHIVLYLKDVMERFWLEIHTSWAQESDSIIAFDNVSLSLGCYLTSNGELPL
QTVSYLSSNL------LME-----SSNQRLNDT------EGDEQHTEILLSTGYWHFTTC
GATGPYGPSQKLCDDTYKNFSV---VYGNGGLKGVQMWRVPETNTYRISGYGAAGGNGGK
TPT-LAQGISLIGIFELQKDEILYILVGQKGEDACPRANSVLQMVCIG------ENTEIE
DELRINGSVSEWAGGGGGGGGATYVFKMESGKPVPLLIAAGGGGRAYRSKASVIPPERLE
SNYTIPGMNGKS-GAAGGGGGWNDHTALPWAGKSLMEGAIGGESCPQAVKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAEGNSAE--M---DGLEGVSFIS-PRGVV-YTPPLKVIE
GHGEVEIKLHLNCSHCEMDECLLDPESKRIVCLCERGTVLAEDGVSCIDEALAPAQETHL
PLSLVLSIVTSALVAALILAFSGIMI--VYRKKHQELQAIQMELQSPDYKLSKVRTSTIM
TDYNPNYCFAGKV--------TSIGDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1510)

ISLIRGLGHGAFGEVYEGQVLGTPSD
PNPLKVAVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRQT-RPRLNQPSSITMLDLLNVSCDIAHGCKYLEENHFIHRDIAARNCLLTCQ
GSGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYNLIRGLLRKSNSDLLRFSSVV
SL-------EPHKIHISSLLRTSYGDLRF-----S----SVVSLEPHTVISLLRTSYSDL
RFSSVV-----SLEPHTVMTSYSDFLRTLS-------------------VVSLGTCLTKT
YSVAVL-K----------------ILISFLRSFTGKTVVKTPGPPDKP--TPEKENPPSS
VTEGNCTAANRV--AGSRLPG----SSLLLEPSTLTSNVQEVPLFRLRHFPCGTVNYGYQ
QQGLPIEPPM----APPPCPQKDSAPRSTSSSAQEKL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------HSPSEAPTDTPSPPPDHFT------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLH

PF00629 // ENSGT00760000118818_8_Domain_0 (314, 473)

DLG---NQSWSWRRVPSEEASQMDLL-DGPEAERSQEMPRGAFLLLN
TSADSKHTILSPWMRSSSERCTLAVSVHRHPQPSGKYAAQLLPHNEA-GR-------EIL
LTP----TPGKHGWTVLQGRIGRPENPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSR
GSKMALQSTFTCRDRTVLQLG------------------RACDFHWDCAQGEDEGQLCRR
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFEDGFCGWTQDTLSP-HAPQWQVGTLK-DVQLRDHQGHALQLSTTDGPAAQS
AT-VTSATFPA-PMKNSP-CELRMSWLVRGVLRGNVSLVLVENRTGRAHDRTVWHVGA--
--SEGLGLWQWTVLPLLDVSDRFWLHTVVWWERGSRATVAMDNVSLSLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDRT
PPD----I-APKSRNLFER-----NPNKEWKPGEA------APQHTPIFDPTAHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVRVGGEGPLRGVQIWRVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMVRSHGVSVLGIFPLQKGDSLYILVGQQGEDACPRTNQLIQKVCIG------ENNVIE
EEIHANGSVHEWAGGGGGGGGATYVFQMKDGVPVPLLVAAGGGGRAYGAKSDTFHPERLE
NSSSVRGLNGHS-GASGGGGGWSDNTSLLWSGKSLLEGATGGHSCPQATKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGDAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHVDPESHKVICFCDHGTVLAEDGVSCVASPT---PEPRL
PLSLILSVVTSALVAALVLTFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRRHI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLLRGLGHGAFGEVYEGQVSGGPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGVFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTGGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIDYCTQ-DPDV--INTALPVEYGPPVE-----EEQKVPTRPKDPEGAPPLLVSPQQAR
RGEHG--PAAP--PPLPTT-APGKAGRKA-PAG-------EPPSHPPGGPAVEGGHVNMA
FTQSNP-PSELHTAQGSRNKPTSLWNPTYGSWFTEKPAKKNSPPA--EKGQLER---AGP
GREGGHPIPP-S-VAAGRLPG----ASLLLEPSSLTATMKEVPLFRLRHFPCGTVNYGYQ
QQGLPLEAPA----APGAGRYEDTVLKSQRGTGQPEP

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------------------------------------------------------------
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--MLFSLPSTVSSWTVLHGRIGRPENPFRVALEYISSAI------LLFSINLCSGHRPSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGPLSP-HIPRWQVRTLK-DAHSQDHQGHVLLLSTTDALTSES
AT-MTSATFPA-PMKNSP-CELRMSWLIHGALRGNVSLVLVENKTGKEQSRTVWHVAA--
--DEGLSLWQWTVLSLLDVTDRFWLQIVTWWGPGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEEKM
PSN----A-VPKSRNLFEK-----NPNKEPKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPEGMPPLLVSPQPTK
QEEAP---AAPQPAALAA---P-------------AG--AGAAASRVPRGAADRGHVNMA
FSQPNPP-PELHKSTGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP------SAE---PQ-
ARAGAAEGGWTRPGEGPRRPG----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA-----AP----GDPVMKSKNKVTQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------TSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGVMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF00069 // ENSGT00760000118818_8_Domain_6 (1236, 1501)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRLSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTVA--------EVSVRVPRGLAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-IATGRLPG----ASLLLEPSSLTTNMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

MEA---IGFLWLLLTLQSL----------LSVASGFGTGSSRGTGSLPGGPPVQPREPLS
YSRLQRKRLAVDFVVPSLFRVYTRDLLLPPF----SPSDLRSGRPEARSSLALDCSPLLA
LLGRLPTVSRTGGATS-SPAPARTLSRVLKGGSVRKLRRAKQLVLELGEEAIIEGCVGLP
E-ETAEGLLQFNLSELFNWWILHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIIGTGH--SSSGSPTST---ASD------SFAWNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHEHG---NHSWSWRRVPSEEASQTDLL-DGPEAEHYKEMPKGSFLLLN
TSANSKHTI-SPWMRSSSEHCTLAVAVHRHLQPSGRYVAQLLPHSEA-GR-------EIL
LAP----SPGKHGWTVLQGRIGRPANPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHPDCSQGEDEGRLCSN
LPPGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CDFEDGFCGWTQSTLLP-HTPRWQINKLQ-DARFQDYQGQALLLSTNDAPTSES
AT-MTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLMLVENKTGKEQDKMVWHIAT--
--NEGLSLWQWMVLPLLNVSDRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEDKV
SQN----T-APKSRNLFDR-----NPSKELKPWEN------TPRDTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVMVGNEGPLKGIQIWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTSQVIQKVCVG------ENHVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPDSHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF00069 // ENSGT00760000118818_8_Domain_6 (1235, 1725)

ITLIRGLGHGAFGEVYEGQVSGMPND
PGPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQSSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-DPDV--INTALPIEYGPVTE-----EEEKVPMRPKDPEGIRPLLVSPQQAQ
REGER-SPGAPPPPPN--P-ASGSAGKKA-AAA-------VVPGRGPRGLAREGGHVNMA
FSQSNP-PSAVHTVQASRNKPTSLWNPTYGSWFTEKPARKNTPVARR----DDR---ESP
GREGGCAAPP-S-AAPGRLAG----ASLLLEPSSLSARVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEPTA----SPGTSSYKDSVLKSKNSGTQQGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MDTPHLLQGRIGRPDSPFRVALEYISSGNRSLSAVDFFALKNCS-EGTTP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTHSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDVPASES
AT-VTSATFPA-PMKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKI
PQK----T-APKSRNLFER-----NPNKELKPGEN------SARQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQMWKVPATDTYRCGRWGEGGSH---
-VVGRGGGGGGEGRGGLEKGRRQ--GQAQRSLEGGISTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGG------QDDTFHPERLE
NNSSVLGLNGNSEGLVGNGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKGSP
SEN------W---------------------CDCQ-----WPPGTCLPVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSHQVKR
G-EEERGPAAP--PPLPTT-SSSKAAKKPT-AA-------EVSVRVPRGPAVEGGHVNMA
FSQSNQ-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPPNV--ATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--FLL--------------------------------------------IFSFS-LGSAS
LSKMALEGSFSCWNGTVIRLG------------------QACDFIQDCAEGEDEGDMCRK
LPSGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CSFEEEDCGWMPGSSVS-HPSPWRIGRPE-HNRFPSIEGCALLLNTSKAPAVAK
TV-MTSMAFPA-PLRNSP-CELRMSWLIHGVLLGNVSLVLVENKTGKEQSWSFWHSEN--
--REGLGIWQWTILPLPEILDRFWFQIIASWEEGSDAIIAFDNVSLSLDCYLTISGE-KI
PR-----GTPPDSSNLLTI-----RGGQKKFGWEQKLLGNLQLSSAPFSDPADQWLFTTC
GASGPYGPTQSQCNDAYRNSKLRVVVGAEGILQGIQIWRVPATNTYSISGYGAAGGKGGK
NTMVRSHGVSVLGIFDLQKDDTLYILVGQQGEDACPSTNDVIQKVCIG------ENNVIE
EEIRVNRSVSEWAGGGGGGGGATYIFKMENGEPVPLIIAAGGGGRAYRAKTDTFHPERLE
NDSSIPGLNGNS-GAAGGGGGWNDNTSFLWSGKSLLEGATGGRSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAVDNDPE--M---DGEDGVSFIN-PIGTL-YTPALKVTE
GHGEVEIRLHLNCSHCEMDECHVDLETQKVICFCEPGTELAEDGVSCTD--A-AEPVVRL
PFSLVLSVVTSALVAALILAFSGIMIGLVYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKNIS

PF00069 // ENSGT00760000118818_8_Domain_6 (1237, 1501)

LIRGLGHGAFGEVYEGQVTGIPSD
PTPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLSMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCR
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPSAE-----EEEKVAMCPDEPEGIPPLLVSTHQDR
KDDKQSLP---SPPPLPSAVTAGKALGKVGA-------LE-QPVPGKVQSGTVGGHINMA
YAQSNP-PSELHKSRGSRNKPTNLWNPTYGSWFAEKQAGKNTSLLEKE--RPER---ESL
GQEGNCTVGPNI--VTGRLPG----SSLLLEPSSLTASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLESST----PPCASGYEDPVLRNKSHITQQGP

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MSL--------------------------------------------CVSAL-PGMPP
ISKMALKSSFTCWNGTAIHLG------------------QACNFQRDCSEGEDEGELCKA
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CDFEDGDCGWIQGMTMP-QTPQWQVGILT-DAPFPNHQGYTMLFNTSKASPAET
VV-LTSNMFPA-PMKNSP-CELQMLWLIHGSLEGNVSLMLMENKTGKEQSQTIWYFAN--
--REGLGIWQRMVLPLPDVSDRFWLQIVTWWEEGSGAIIAFDNISLSLDCYLTINGEEKI
SK-----DEAPNSSNLFDI-----NSYKKPLQDPRS--KKTSHGEILNFDPTVQWLFTTC
GASGPQGPTQTQCNNAYRNSNLSVVVGSEGVLKGVQIWRVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGVFDLEKDDFLYILVGQQGEDACPSTSEIIQKVCIG------ENNVIE
EEIRANQSVNEWAGGGGGGGGATYIFKMKNGIPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAVNNDPE--V---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKLYLNCSHCEVDECHIDPESHKVICFCEHGTVLAEDGVSCIVSPP-SEP--HL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

SLIRGLGHGAFGEVYEGQVSGIPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCS
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQCWQHLPEDRPNFATVL
ERIEYCTQ-DPDV--INTALPIEYGPVTE-----EEEKVPMRPEDPDRIPPLLVSPQQEK
KEAACAPS---APPPL-ATTSSGKPLKKALA-------LE-PPVRITRGAPVEGGHINMA
YSQSNP-PSELHKGRGSRNKPTSLWNPTYGSWFTEKSAPKNSPRAEPE--QPER---GKA
GPEGHCTPGP-----PGRLPG----SSLLLEPSSLTSSMTEVPLFRLRHFPCGNVHYGYQ
QQGLPLEAGA----TPAAAGYGDSALRNPSGGSQAGP

MGSVGLLG---LLLLRLSVTASGSGAGTGSGTGSGTGTGTGQLVGSPATGPALQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPW----SSSEPRAGWTEARGSLALDCAPLLR
LLGPPPGVSWAEGASSPAPAQARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPS
PEEVTAGLLQFNLSELFSWWIRHGEGRLRIRLMPEKKASAVGREGRLSAAIRASQPRLLF
QILGT--GHSSLESPTSLPSPPPDPFA------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHDLG---

PF00629 // ENSGT00760000118818_8_Domain_0 (320, 474)

NQSWSWRRVPSEEASQMDLL-DGPETEHSKEMPRGSFLLLN
TSANSKHTILSPWMRSSSEHCKLAVSVHRHLQPSGRYVAQLLPHNEP-GR-------EIL
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSQ
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFENGFCGWSQGILTP-HNPRWQVRTLK-DARVQDHRGHALSLSTTDVPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIHGVLRGNVSLVLVENKTGKEQSRMVWHVAT--
--NEGLSLWQWTVLPLLDVADRFWLQIVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 825)

CYLTISGEEKM
LQN----T-APKSRNLFER-----NPNKDPRPWEN------T-RETPVFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATD

PF12810 // ENSGT00760000118818_8_Domain_5 (825, 1064)

TYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFI

ENSGT00760000118818_8_Linker_5_6 (1064, 1236)

S-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEGDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPSD
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPLME-----EEEKVPMRPQDPEGIPPLLVSPPQAK
R-EEGPDPAAP--PPLPST-SSGKAAKKPT-AA-------ELSGRVTRGPAVEGGHVNMA
FSQSNP-ASELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPA--TKGHHDR---GNL
GREGSCTVPPNV--AAGRLPG----ASLLLEPSSLTASMKEVPLFRLRHFPCGNVNYGYQ
QQGLPFEGTT----APGSSQYEDALLKT---------

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-------------WTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCARGEDEDQLCKK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWSQSTLSP-HIPKWQVNTLK-DTRSLDHQGGALLLSTTDAPTAES
AA-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMLWHVAT--
--DEGLSLWQWTVLPLLNVSDRFWLQLVTWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----P-APKSRNLFER-----NTHTETKPKGN------GPEQVPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGVQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TNTYSISGYGAAGGKGGK
NAMTRSHGVSVLGVFNLEKDDALYILVGQQGADACPSTNQLIQKVCIG------ENNVIE
EELRANRSVREWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAALNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPETHKVICFCDHGTVLAEDGVSCIASPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMAND
PNPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLVMLDLLRVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-VQMS--FSP------------------------------------------
------------------------------------------------------------
-----------------ESKPPSLW-----------------------------------
------------------------------------QTTGDVPLFRLRHFPCGNVNYGYQ
PRAVPPEPGL----RAKAKA---------KAASPPAP

MGT---IGLLWLLPLLLST------------AALGSGTGTGQRTGSPAAGLPLQPREPLS
YSRLQRKSLAVDFVMPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDAPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGNEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTAA--------EVSVRVPRGLAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGAGHYEDTILKSKNSMNQPGP

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-----------------------------------------------------GSFLLLN
TSANSKHTILSPWVKSSSEHCRLAVSVHRHLQPSGRYVAQLLPHNEP-GR-------EIL
LVP----TPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHRDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CNFEDGFCGWTQGTLAP-HNPQWQIRTLK-DVRGQDHRGHALLLSTTDVPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHVAT--
--NEGLSLWQWTVLPLLDVADRFWLQIVAWWGPGSRATVAFDNISISLDCYLTISGEDKM
PQN----T-APKSRNLFER-----NPNKEPKVWEN------T-RETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGK
HTMMRSHGVSVLGIFNLEKGDTLYILVGQQGEDACPSTNRLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHAERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--I---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEGDECHMDPESHKVICFCDHGTVLADDGVSCIVSPT---PEPHL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQLELQSPEYKLSKLRTSTIV
TDYNPNYCFAGKT--------SSISDLKEVPRKN

PF07714 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ITLIRGLGHGAFGEVYEGQVSGVPSD
PXXLPFCAQTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--IHTALPVEYGPLLE-----EEEKVPVRPQDPEGIPPLLVSAPQAK
R-EERQEAAAP--PPLPSV-SSGKAVKKPA-AA-------ELSVRGARGPAAEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPAKKNNPPA--KKERHER---GTP
GREGSCTVAAPV--APG-APG----ASVLLEPSSLTASVKEVPLFRLRHFPCGTVNYGYQ
-------------------------------------

MGT---IGLLWLLPLLLST------------AALGSGTGTGQRTGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SPSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--TPAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNIPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPL

PF00629 // ENSGT00760000118818_8_Domain_0 (313, 473)

HDLR---NQSWSWRRVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLN-DARFQDHQDHALLLSTTDASTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDAFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EEEKVPVRPKDPEGVPPLLVSQQAKR
GE-ER-SPAAPPP--VPTT-SSGKAAKKPTAA--------EVSVRVPRGPAVEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPLA--KKEPHER---GNL
GLEGSCTVPP-N-VATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAAT----APGAGHYEDTILKSKNSMNQPGP

MEASVLLW---LLLPLLSTAAL------------GSGTGTGPRSGLQAVGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPPS-----PSELRAGRPEARGSLALDCAPLLR
LLGPPPGVSGTVGSSSPAPAAARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
-EEPAAGLLQFNLSELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSTAIRASQPRLLF
QIFGT--VHSYLESPTNMPSPPPDYFA------WNLTWIMKDSFPFLSHRSRYGLECSF-
DFPCELEYSPPLHNLR--

PF00629 // ENSGT00760000118818_8_Domain_0 (319, 473)

-NQSWSWRHVPSEEASQMDLL-DGPEAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSERCTLAVSVHRHLQPSGRYVARLLPHNEA-GR-------EIV
LVP----TPGKHGWTVLHGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCS-EGTTP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCRK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTPK-DAPFQDHQGRALLLSTTDVPTAES
AM-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLLLVENKTGREQSRLVWQVAA--
--SEGLSLWQWTVLPLLDVSDRFWLQIVAWWGQGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
SQN----A-APKSRNLFDR-----NPNVELKPLEN------IPRQTPDFDPTVQWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGLFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENHVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDAFHPEKLE
NNSSVLGLNGNS-GAAGGGGGWHDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGVL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHRVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLVLSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLLRGLGHGAFGEVYEGQVSGMPSD
PSPQQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLME-----EEEKVPVRPKDPEGIPPLLVSPQQAK
R-EEERGPAAP--PPPPTT-SSGKAVKKPT-AA-------EVSVRVPRGPVAEGGHVNMA
FSQSNP-PSELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPVA--KKQQQER---GNL
GREGSCTVPPNV--ATGRLPG----ASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGTSHYEDTILKNKNSVNQPGP

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----SWTRRKHGWTVLHGRIGRPEHPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFRRDCAQGEDEGQLCSQ
LPASFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CHFEDGFCGWTQGTFSP-DVPRWQVRTLK-DAWSQDHQDHALLLSTTEIPGPES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGALRGNVSLVLVENKTGKEQSRMVWHVAT--
--NKDLSLWQWTVLPLLNVSDRFWLQMVAWWGQGSRATVAFDNISISLDCYLTISGEDKL
LQG----E-EPKSRNLYDR-----PPDNEP-PSEN------VPRQTATFDPTVHWLFTTC
GASGPHGPTQTQCNNAYQNSNLSVMVGSEGPLKGVQIWKVPATDTYRCPYAGAGT-----
----------QVGRSFLSKDDVLYILVGQQGEDASP-TNHLIQKVCVG------ESNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWDDNTSLLWAGKSLLEGATGGHACPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GSGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPPVE-----EEEKVPMRPKDPEGMPPLLVSPQPAK
QE-EARIPAPALPPPLSTV-ASSDKAVKKPAAA-------GVSVQGPRGPATAGGHVNMA
FAQSNP-PPELRRVQGSRNKPTSLWNPTYGSWFTEKPAKKNNPPP--KKEPQPQ---GST
GRAESCTVPPNATTSTGRLPG----ASLLLEPSSLTASMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATT----APGAGHYEDTILKNKNNTGQPGP

MGA---IGLLWLLPLLLST------------AAVGSGMGTGQRAGSPAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLP-P----SSSELKAGRPEARGSLALDCAPLLR
LLGPAPGVSWTAGSP--APAEARTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPP
G-EAAVGLLQFNLSELFSWWIRQGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLF
QIFGT--GHSSLESPTNMPSPSPDYFT------WNLTWIMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHDLR---NQSWSWRRVPSEEASQMDLL-DGPGAERSKEMPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGRYIAQLLPHNEA-AR-------EIL
LMP----TPGKHGWTVLQGRIGRPDNPFRVALEYISSGNHSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQMCRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVRTLK-DARFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLRMVAWWGKGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLQEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1431)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDT--------
------------------------------------------------------------
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-------------------------------------

---MGALELLWLLPLLLSA------------AASDSGAATDQRAGSLAAGPPLQPREPLS
YSRLQRKSLAVDFVVPSLFRVYARDLLLPQ---PPSPSEPGAGGLEARGSLALDCAPLLR
LLGPPPGVSWVEGASSPSPEVGSTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCIGPP
EEATAVGILQFNLSELFSWWIHHGEGRLRIRLMPEKKASEAGREGRLSTAIRASQPRLLF
QIFGT--GHSSLKSPSGMPSPPDN-------FVWNLTWTMKDSFPFLSHRSRYGLE

PF00629 // ENSGT00760000118818_8_Domain_0 (297, 473)

CSF-
DFPCELEYSPPLHNHG---NQSWSWRRVPSEEASQMDLL-DGPEADRSKETPRGSFLLLN
TSADSKHTILSPWMRSSSEHCTLSVSVHRHLQPSGRYVAQLLPHNEAGRE----------
--ILLVPTPGKHGWTVLHGRIGRPENPFRVALEYISSGNHSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDEGQLCSK
LPAGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGPLSP-HMPRWQVRTLK-NAHFQDYQGQALLLSTTDVPTSES
AT-VTSATFPA-PMKNSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQSRTVWHVTT--
--DEGLSLWQWTVLSLLDVTDRFWLQIVTWWGPGSRATVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKM
SSN----A-APKSRNLFEK-----NPNKEPKSWAN------ISGPTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLRGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDEMLYILVGQQGEDACPRANQLIQKVCVG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGAAGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCEHGTVLAEDGVSCIVSAT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPVVE-----EEEKVPMRPKDPDGIPPLLVSPQPVK
HEEAP---AAPQPAALAA---PGPLVKKPPGAGAGAG--VGAGTVRVPRGAADRGHVNMA
FSQPNPPPPELHKSAGSRNKPTSLWNPTYGSWFTEKPAKKTHPPP--PPPPGAE---PQ-
ARAGAAEGGWTGPGAGPRRPG----AALLLEPSALSATMKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEATA----AAP----GDTALKSKNKVTQPGP

------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
-----------------------------------------------------------M
PQN----T-APKSRNLFER-----NSNKESKPWEN------TPGETPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSVSAQSRAWFLAQWAALEQGAALS
KSEGVGGGARRWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASDNDPE--M---DGEDGVSFIS-PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDPESHKIICFCDHGTVLAEDGVSCIVLLK----PPHL
PLSLILSVVTSALVAALVLAFSGIMI--GE-WRWQHLQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPIEYGPLVE-----EE------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
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-----------------------------------------------------S-LGSAS
VSKMALEGSFICWNGTSIRLG------------------QACDFIRDCLEGEDEGDMCKN
LPPGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 712)

CSFEEGDCGWIHSSSAS-RASPWRIGSPD-YDRFPSIEGCGLIFDTSKAPAAAN
TA-ITSTAFPA-PLRNSP-CELRMSWLIHGVLLGNISLVLVENKTGKEQSRTLWHSAN--
--SKGLGIWQWLILPLPDILDRFWFQIIASWEEGSDAIIAFDNVSLSLDCYLTINGE-KI
PR-----STTPDSSNLLTS-----RGGKKKFGWEQKLLGNLQLSTAPISGPADHWLFTTC
GASGPYGPTQSQCNNAYRNSNLSVVVGAEGILQGIQIWRVPATNTYSISGYGAAGGKGGK
NTMVRSHGVSVLGIFDLQKDDTLYILVGQQGEDACPSTNDVIQKVCIG------ENNVIE
EEIRVNRSVNEWAGGGGGGGGATYIFKMENGEPVPLIIAAGGGGRAYRAKTDTFHPERLE
NDSSVPGLNGNS-GAAGGGGGWNDNTSFLWSGKSLLEGATGGRSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAAEDNDPE--M---DGEDGVSFIN-PIGTL-YTPALKVTE
GHGEVDIRLHLNCSHCEMDECRVDPETQKVICFCEPGTELAEDGVSCVASVT-AEPVVHL
PLSLVLSVVTSALVAALILAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------TSISDLKEVPRKN

PF00069 // ENSGT00760000118818_8_Domain_6 (1235, 1503)

ISLIRGLGHGAFGEVYEGQVAGIPSD
PTPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPNQPSSLSMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCR
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ-DPDV--INTALPVEYGPSVE-----EEEKVAIHPEDPEGIPPLLVSAHQDR
KDDKQTLP---SPPPLPSAITAGKALGKAGA-------LE-PPVPGKVQSASAGGHINMA
YTQSNP-PSELHKGRGSRNKPTNLWNPTYGSWFAEKQASRNNPLLEKE--MPER---ENL
GHEGNCTVGPNI--VTGRLPG----SSLLLEPSSLTASVKEVPLFRLRHFPCGNVNYGYQ
QQGLPLEAST----PPCASSYEDPALRNKSHITQHGP

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-MP----TPGKHGWTVLQGRIGRPDNPFRVALEYVSSGNRSLSAVDFFALKNCS-EGTSP
GSKMALQSSFTCWNGTVLQLG------------------QACDFHQDCAQGEDESQICRK
LPVGFY

PF00629 // ENSGT00760000118818_8_Domain_2 (547, 710)

CNFEDGFCGWTQGTLSP-HTPQWQVSTLK-DARFQDHQDHALLLSTTDVPTSES
AT-VTSATFPA-PIKSSP-CELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAA--
--YEGLSLWQWTVLPLLDVSDRFWLQMVAWWGQGSRAIVAFDNISISLD

ENSGT00760000118818_8_Linker_2_5 (710, 823)

CYLTISGEDKI
LQN----T-APKSRNLFER-----NPNKELKPGEN------SPRQTPIFDPTVHWLFTTC
GASGPHGPTQAQCNNAYQNSNLSVEVGSEGPLKGIQIWKVPA

PF12810 // ENSGT00760000118818_8_Domain_5 (823, 1066)

TDTYSISGYGAAGGKGGK
NTMMRSHGVSVLGIFNLEKDDTLYILVGQQGEDACPSTNQLIQKVCIG------ENNVIE
EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLE
NNSSVLGLNGNS-GAAGGGGGWNDNTSLLWAGKSLLEGATGGHSCPQAMKKWGWETRGGF
GGGGGGCSSGGGGGGYIGGNAASNNDPE--M---DGEDGVSFIS-

ENSGT00760000118818_8_Linker_5_6 (1066, 1236)

PLGIL-YTPALKVME
GHGEVNIKHYLNCSHCEVDECHMDTESHKVICFCDHGTVLAEDGVSCIVSPT---PEPHL
PLSLILSVVTSALVAALVLAFSGIMI--VYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKT--------SSISDLKEVPRKNI

PF07714 // ENSGT00760000118818_8_Domain_6 (1236, 1502)

TLIRGLGHGAFGEVYEGQVSGVPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAG
GDLKSFLRET-RPRPSQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIIL
ERIEYCTQ----------------------------------------------------
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