Query Results 

MKSICWLTLKP-----VNFVVFGCIIWISVAQGTVLSSCLTSCVTNLGRQLDSGTRYN--
-LSEACIHGCQFWNSVDQETCALKCNDTYATIC--ERESCEVGCSNAEGSYEEEVLENTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGVTLRWNPANISGVKYIIQWKYAQLPGSWTYTETVSKLSYTVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APLILNMESWSPDTVE
VSWAPPRFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESTITT-PSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIHHN
I---TGISVYAQQQVV-----YFSEGTVIWMKGAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YQGSGLVSSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RIYFIMDKLVYVCDLKNCSNLEEITPFSL
IAPQKVVVDSYNGYVFYLLRDGIYRVNLPLPS---GRDTKAVRIVESGTLKDFAV----K
PQS----KRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLV-TVKSFAYENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSVQSYPLPGYPQEVSVL
FGSREALIQWKPPALAIGA------------------------SPSAWQNWTYEVKVYSQ
DILEITQVFSNISRTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWS-GGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSK
FLIIE--------QQSLPIFTVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPES-VPS
APENPRIFILSSGRYTKKNE-VVVEFRWNKPKHENGVLTKFEIFYHISKQS---------
---GTNRSTEDWMSASV---TPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSK
TSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSPEGDVSTVGYT----TDDEMGYF----
AQGDTLFLLNLHNHSS---SKLFQDALVSDIR-VIAVDWIARHLYFALKASQNGTQIFNV
DLEHKVKSPRKVK--TCKGHTTIISFSIYPLLS--RLYWTEVSDLGHQMFYCNISNHTSQ
HVVQPKASN-QHGRSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKR-QEIWAMDLEGCQ
CWKVIMVPAI-P-GKRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKH
ILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTW-HGITHPTSTY
LIYYMEANRA-NSSD---RRHKM-----LESQENVARIEGLQPFSMYVIQIAVKNYYSEP
LEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSY
LAPIPETPLRQGEFPSARLSLLVTKLSGGQLYVMK--VLACHPEEMWCTESHPVSVNMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2247)

TPEKPSALVPENTSLQLDWKAPSNVNLTGFWFELQKWKY--NEFYHVKASCS-QGPVYVC
NITDLQPYTSYN-IRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSIPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSRLM----YYTLEV--RKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNL
KGTFQFRAVAANEIGLGEYSEISEDITLV--EDGVWITETSF--ILTIIV--GIFLVATV
PLTFVWHRSLKSHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIEN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAIDILGMGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTF-HGPSLTLLD
LVELCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQL-FRN
VFLNNVSHCGEAAPISGVINKGFEGEDDE-MVAFNSD-DTMPVALMETKNQEGLNYMVLA
TKCSQGEGSYEGPLGPKELGSCDL-KKDKKQSQADKDFCQEPQVAYGS-PGLSEGLNYAC
LAHSEHGDVSE-

MKNIYCLIPKL-----VNFATLGC-LWIFVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSASFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVESLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSTAAVNEV
GEGPEAQSSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKRLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNVSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVYVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIDRADLPVPS---GRCAEAVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPHIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVRWKPPALAIGANV----------ILTSDIIEPFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFSNISGTMLNVPELQSATKYKVSVRASSPKRPGPWSESSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIRNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHADIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDATIA
EFAAWSISEISQNALMYYSGRLFWINGFRIITTQEIDQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------RHSLPVFTVEGLEPHALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPEHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVNV---TPSVMSFQLEGMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINRTLH
RILQPPATNQQNKRNQCSCNVTEFELTGAMAIDTSNLEKPLIYFAKA-QEIWATDLEGCH
CWRVITVPAMLAG-KTLASLTVDGDFIYWIITAKDSTWIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKVFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVFYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMMQIAVKNYYSDP
LEHLPPGKKMWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPSKPGTPKLLEGSENS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGVFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLIITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINESFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECSQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LTHTGYGDGSD-

MKNICWLILKS-----VNFATLGC-IWISVIQCTVLNSCLKSCVTNLGWQLDIGTPFN--
-LSEPCIQGCHFWNSVDQENCALKCNDTYDTVC--ERESCEVGCSSAEGAFEAEVLENAD
F

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWKSANISGVKYIIQWKYTQLPGSWTYTEAVSKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

AWIFTAQLQLYSLPSPSYRTH-P------SGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APSIRNIESSSPDTVE
VSWTPPQFPGGPILGYNIRLVSKNQQLDSGTQSTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-LSSAVQEEEQWLFLSRKASLRKRSLKHLVDEAHCLQ----SGAIHHD
I---TGISVNVHQQVI-----YFSEGMLIWLKEAANMSDGS-------------------
------------------------------------------------------------
-----------------------------------------------D-----L-----R
-----V------F-----Y-----R------G-----S-----G-----L----------
---------------------------------ISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDALVYVCDLGNCSNTEEITPPSI
TAPQKIVVDPYNGYVFYLLKDGIYRVDLPVPS---GRDSEALRIVESPTLKDFAV----K
PQS----KRIIYFNDTAHVFMSTFLDGSASHLVLAPVSFA-DVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVILGSYAQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQQLSVL
FGSHQALVQWKPPALAIGA------------------------SPSAWQNWIYEVKVSTQ
DFPEITHIFSNISGTMLNVPELQSATKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGELISSDIGNVSDMDWYNNSLYYSDVK
GDVYVWLLNGT-DISENYHIPNISGAGALAFDWLGQFLYWAGKTYVIQRQSLLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYAAVLRGQS-TGETNIT
EFAAWSTSEISQNTVMYYSGRLFWINGFRIITAQEIGQRASVSILEPAKFNQFTIIQTSL
KPLP--GNFSVTPKVIPDSVPESSFRIEGNASSFQILWNAPPAVDWGVIFYSVEFSSHSK
FLASE--------QQLLPVFTVEGLEPYALYNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APRNPRMFVLPSGKYYKQNE-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1523, 1614)

VVEFRWNKPKHENGVLTRSEIFYHITNQT---------
---DTNETFQDWIAVNT---TPSEMSFQLEGMSPGCTVAFQVRVFTSKGPGPFSDIVKSK
TSEINQFPILITLFDNKIVLLDMDQSHIVWMFSAERVINTMGYT----ADDGMGYY----
AQGDSLCLLNMHNRST---SEIFRDALVSDIT-IITTDWISRHLYFVRKESQNGMQIFDV
DLEHKVKYPRKLK--ICNRNSTIVSFSVYPLLS--RLYWTEVSDFGSQMFYYSIINQTLS
HILPSRPTNHSNGKKQCFCGVTEFEFSGTMTIDTSDLKKPWIYFVKG-QEIWATDLEGCQ
CWQVIMVPTP--LGKTLESLTVDGEFLYWISSTKDSTEIYQAKKSNGAILSQMKAQRSKR
ILAYSSVLQPFPDKALLCLASDTAEPILLNTTNTSLTIRLPPARTNLPWLSGITPPTPTY
LVYYKEVNGRKTSPE---LKYKM-----LEFQERIVLIDGLQPFSTYVIQTAVKNYYSDP
MEQLPVGKEIWGKTKSGVPEAVRLINTTVQSDTSVLISWRESHKPNGPRESVRYQLAISH
LALVPETPLRQRDYPDGRLALLVTRLSGGKLYVFK--VLACHAEEMWCAESHPVTVKMFD
TPEKPYALVPENTSVQLDWTAPSDVNLIRFWFELQKWKY--NEFFSVNASCF-QGPTYVC
NITDLQPFTAYN-VHVVVI-YETGENSTSLPESFKT----KAGVPSQPGIPEVLEGSKDS
IQWGKAEDNGSRLL----YYILEV--RKGISNDSQNQNLMWKMAFNGSCSSICTWKSKNL
KGTFQFRVIAANDLGFGDYSGISENIILAG--DVFWMPETSF--ILTIII--GIFLVVTV
PLVFVWHRKLKNQKAPKEGLTGLINEDKELAELRGLAAGVGLANACYAIHTLPTQAEIES
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGTGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKTGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPTHSNLDVLNYVQTGGRLEPPKNCPDDLWNLLTQCWAQEPDQRPTFHKIQDQLQL-FRN
VSLNGISQCREEADHSGVINEGFEDEDGS-VICLNSG-DITSIALTETKNQEGLNYMVLA
TECSQGEENSEGPLGSKESGSCGL-TKEEKEPHADKDPCQEKQVAYCP-PGNPEGLNYAC
LTHSGYRDGSD-

MKNIYWLILNP-----FNFATLGY-LWISVVQCTV-NNCLKSCVTSLGQQLDVGAPYN--
-LSEVXXXXXXXXXX---------XXXXXXXXX--XRESCEVGCSGAEGAYEEEVLENAG
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 204)

PLA-PFASSIGTHHVTLRWKSANISGVKYIIQWKYTQLLGSWKYTEAVSNLSYVVKDLH
PFTEYVFRVVWIFTAQLQLYSQP

ENSGT00760000118818_6_Linker_0_1 (204, 218)

SPSYRTH-P-----

PF00041 // ENSGT00760000118818_6_Domain_1 (218, 306)

-YGVPETAPFISNIESSSPDTVE
ISWVPPQFPGGPILGYNLRLMSETQKFHSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESSITT-SSSAXXXXXXXXXXXXXXXXKKRSLKHWVDEALCLQ----SDAIHHN
I---TGISINVHQQVV-----YFSEGTLIWVKQAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISTDWLNQ----------------
------------------------------------------------------------
-------------------------------RIYFIMDELVWVCDLENCSNIEEITPHSF
TAPQKIVADSYNGYVFYLLRDGIYRVNISTPP---GRDSEAVRIVESHTLKDFAV----K
SQS----KRIIYFNDTARVFMSTFLDGSATHLVLPHASFAADVKSFACESNNFLVTDGKA
VFQQ-----DSMSFNEFIVGCDLNH----IEEFGFGNLVIFGSYSQPYPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGRPQKLSVL
FGSNKAFLQWKPPALPIGVNVI-----------LVRIIVFFWLGTSSWQNWTYEVKVLNQ
HLPEITHVFSNISETMLNISQLQSATKYKVSVRASSPKGPGPWSEPLVG--TTLVPX---
------XXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXMDWYNNSLYYSDTK
GDVYMWLLNGK-DTSESYHIPNIAGAVAVAFEWLGHYLYWAGKKYVXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX----------
------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGNTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIDQRTSVSVLEPDKIKLFTIIQTSL
KPLP--GNFSFTPKVIPDSVKESSFRIEGTASKFQIQWDAPPAVDWGTTFYSVELRSHSK
FLASE--------RQSLPVFVVEGLEPYALFNLSVIPY-YWGKGPXXXXXXXXXXX-X

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1609)

PS
APENPRIFILPNEKHSTMNE-VVVEFRWNKPKHENGVLTKFEILYQISNQN---------
---DTNITLEDWIAVNV---TPSVMAFQLKGMSPGYTVAFQXXXXXXX

ENSGT00760000118818_6_Linker_4_5 (1609, 1940)

XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXILLLDMDQNQVLWTFVAEREINAMSYT----ADNAMGYY----
AQGDSLFLLNMHNQSS---SEIFRNALVFDIT-IITIDWISRHLFFVLKESKNGMQIFDV
DLEHKVKYPRKLK--FCNRNSSIISFSVYPFLS--RLYWTEVSNLGSQMFYCCMINRTLH
RILQPTATDQSSKRSQCSCSVTEHELSGIMTVDTSDLKKPQIYFIKG-QEIWATDLEGCQ
CQHIILMPDLL-VGKKLASLTVDGEFLYWIVTAKNSTLIYQARKSNATVLSQVPAQQSKH
IVAYSSVVQPFPDKAFLSL

PF00041 // ENSGT00760000118818_6_Domain_5 (1940, 2038)

ASDIAEPTILNNTNTSLMIGLPPARTKLLW-HGITNPTPTY
LVYYQEVNGGKNGSK---LQYKM-----LEFQESTALIEGLQPFSTYMIQIAVKNYY

ENSGT00760000118818_6_Linker_5_6 (2038, 2059)

SDP
LEQLPLGKEIWGKTKSGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2146)

PEAVELINATVQSDTSLFISWRESLKPHGPKELIRYQLAISH
LALIPETPLRQSEYPNRRLALLLPGLTGGKSYVLK--VLACHSEEMWCSESLAVTAETFE
SPERPSALVPENTSLHLNWKPPSNVNLIKFWFELQKXXX--XXXXXXXXXXX-XXXXXXX
XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX-XXXGVPSKPGIPKLLEGSKNS
IQWDKAEDNGSRLL----YYILEV-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGFWIPETSF--VLTIII--GIFLVTTV
LLIFVWYRRLKKKKPPKEGLSVLINEDKELNELRGLAAGAGLANACYAVHTLPTQEEIES
LPVFPRDK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LTLRLLLGSGAFGEVYEGTAVDILGIGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTS-HGPLLTLVD
LIDLCIDISRGCVYLEQMHFIHR-DLAARNCLVSVKDYTSRLRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGNQP
YPALSNLDVLNYVQTGGRLEPPKNCPDDLWNLMNQCWAQEADERPAFQKIQDQLQL-FRT
VSLNSISQCIPEANANGVINEGFEDEDGC-MTCLKSD-DVISVALMEIKNQDGLNYMVLA
TERSQGEENSEGMLSSTEPESCGL-GKEEMEPQADKDIRQI-TVAYC-------------
------------

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTETVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTMYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAETVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTRIFSNISGTRLNVPELQSATKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYNVEFSAHSK
FLASE--------RHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVDV---TPSVMSFQLEGMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSAYPLLS--RLYWTEVSSFGYQMFYYSIINCTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCH
CWRVITVPAML-G-KTLASLTVDGDFIYWIITAKDSTRIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-YGITSPTPTY
LVCYAEVNDRKNNSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
APEKPYSLVPENTSLQFNWKAPSNVNLIRFWTELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGENSTSLPESFKT----KAGVPGKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEI
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VVCLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

------------------------------------------------------------
-----CIQGCQFWNVTVQTDCLLKCSSVSMKRC--NTVSCKFGCSCAEDAYGVEALSYLN

PF00041 // ENSGT00760000118818_6_Domain_0 (121, 190)

KPSA-PFASVIGNHSVTLGWKAANISGVKYVIQWKFNKLPGDWRYTEVVSATSFTVKDLQ
AFTEYVFQV

ENSGT00760000118818_6_Linker_0_1 (190, 231)

VWIVTSQLQLHSPPSPSYRTHA-------FGVPATAPVIKD

PF00041 // ENSGT00760000118818_6_Domain_1 (231, 305)

IQSSSPNTVE
VSWSPPLFPNGLIIGYNLHLTSENHELLRASRGHSFQFYSTFPNTTYR---FSIVAVNEV
GAGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

PTEANITTPASKV-KEKGAWLFLSRKESLRKRYTGHFLEAAQCLP----DGIIHHN
I---TGISVNIYQQVV-----YFSEGNSIWVKGVANMSDVSDLMLF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YAGWGNIVSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RIYFVMNEKIHVCHLENCTVAEDVTPLYV
TSPRKVIADPYNGYIFCLLEDGIYRANLPLLP---GTASAASLVVRSNALRTFTI----N
FQS----KRLIFFNKTEQAFVSGFLDGSEFHTLRSHVPFN-DMESFVYKDNTFTVTDGSA
VFHEEVSPVGSSSFNEYIVDCNLVY----PEYFGIGNLVFYGPSTQPSPLPT

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

APRLVTAL
FGSDRAVISWRPPEHSIGTS------------------------LSAWQNWTYNVKVSPQ
HPFEEDWVVSNISNTRLIVKGLASFTAYEVSVRAVSPAGAGPWSESFRG--TTLEE----
--------AEEEPYILAVGPEGLWKQQLDSYRQGELLYPHIRNVSDLDWYNNTLYWINSM
GEVQTWTLNKRKGINENTYVSDVRNARMLAFDWLGQYLYWAGKANTIYRKSLWGGHIDVV
AHVVFPVKDLVVDSINGYLYWATMYSVESTRLNGEEYFMLQEQLQFSGKQ----------
------------------VVGVTLDLTYGFLYWLVQDSLCLNLYRASLCKEG-CSNAIIT
EFAAWSTSEISQGALEYYSGRLFWINRLQFITVQEVNQSLSIPFSQPAQFTAFTLVQATL
KPLP--GNFSSMPKVIPDSVPESSFRIKGNSTSFHITWSPSTKVEWGTVFYCVGSKAL--
----QSEGCLHPHNLTVPSYRVDWLEPFALFDFTVTPYTYWGKAPMTSVSLRAPEG-VPS
APRNPRIYVLQNSLHRSDSK-VL

PF00041 // ENSGT00760000118818_6_Domain_4 (1524, 1614)

VEFRWDRPERDNGILMQFRVYYQIVNQS---------
---STAGTFTEWIESNV---KPTQMQFSLKDVLPSLTVRFQVQAFTSVGPGPMSDMAERN
SSDLSPIPTLITISANKLFLTDIDSGHTIWELSAKTNVKDICYT----ANDDKAYH----
VTEDSLFILNIQNASM---FQFFKDVHLHNVT-AITVDWIARHLFVALKTPQNETQIFLI
DLELKEKSLKALNKQLSKSNSTVSSLLSYPFLS--RLYWMEEFDHGSHMFYYDILNNTIH
HILGHSLVE-KQTRNYCTCNVTEAELGRPMSIDLSDSKNPQLLFIRGGDEIWASDVDGCH
CWRTIKIPSIQ--GNKIGSLTADKTFIYWTIETKEYAEIWLANKESRRHFLHKRANHTLK
ILAYSSAAQSYPDKRCLILLPDTEKPTILAMTNTSFTLSLPSVTPQQLC-PGISQTTPTY
LVFSRQMTNICRNSR---QLS----LKIIEYQGPIAVLENLQPFSSYAIQVAVKNYYSDE
E-VLPVGEGTVGTTLYGVPEAVNTIKTLVLSDTTINISWSEPLKPNGPLESIRYQISVNL
LPPVPATPLRKSEFSNGMLAWSVSGLQSGTNNSFK--VLAFHPDENWFSESVPVIAKTFE
TPAAPMNIVPRNTSFQLEWRAPLHISETSFWFELCKWPTKSDWFSPANTTCV-GNLVYKC
NLTGTQPWTNYF-VRVTVV-YVTGVKSTSSSTSFKTT----VGVPSKPGVPKRAEDPKNS
LQWEKADDNGSKLT----YYILESRKQS---GNSSDVKSMWEVVYNGSCGNICTWKAKNL
QGTFQFRAAAANVLGLGEYSDISMDIILSE--GMSY-I-R--ITSSLQTEFVVLCLAVVM
LLGFVWKKRLKSRKSALPGQIVFIKEDKELAQLRGMAETVGLANACYAVRTLPSQAEIES
LPAFPRNKLN

PF00069 // ENSGT00760000118818_6_Domain_9 (2471, 2750)

LHKLLGSGAFGEVYEGTAVDILADGSGESKVAVKTLKKGATDHEKSEFLK
EAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKKKL-QSPLLRVTD
LLDICLDVCKGCVYLEKMHFIHR-DLAARNCLVSEKEYECSSRVVKIGDFG--LARDVYK
NDYYRKRGEGLLPVRWMAPESLIDGVFTSHS----------DVWAFGILVWETLTLGQQP
YPGFSNTEVLHHVRSGGRLESPNNCPDDLCDLMTRCWSQEPHNRPTFSYIHDKLQE-IRH
SPLSFMHCLEDKKASIGVINEAFEAEDND-IPCADSD-SILSATLMETRNQEGLNYLVLV
KE----------------------------------------------------------
------------

MKSICWLTPKP-----VNFVVLGCIIWISVAQGTVLSSCLTSCVTNLGKQLNSDSRYN--
-LSDACIHGCQFWNSVDQEKCAAKCNDTYTTIC--ERESCEVGCSNAEGSYEEEVLESTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGVTLRWNPAKVSGVKYIIQWKYAQLPGSWTYTETVSKLSYTVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIVTTESWSPDTVE
VSWAPPRFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESTITT-PSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIHHN
I---TGISVNAQQQVV-----YFSEGTVIWMKGAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YQGSGLVSSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVYVCDLKNCSNFEEITPFSL
IAPQKVVVDSYNGYVFYLLRDGIYRVNLPLPS---GRDTKAVRIVESGTLKDFAV----K
PQS----KRIIYFNDSMQLFMSTFLDGSAFHRVLPWVPLV-NVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSIQSYPLPGHPQEVSVL
FGSREALIQWKPPALAIGA------------------------SPSAWQNWTYEVRVHSE
DILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSVVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWS-GGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTAL
KPLP--GNFSSTPKVIPDSVQESSFRIEGHTSSFQILWKEPPAVDWGVIFYSVEFSTHSK
FLVIE---------QSLPIFTVEGLEPYTVFNLSVTPYTYWGKGQKTSLSFRAPES-VPS
APENPRIFILSSGRYSRKKE-VVVEFRWNKPKHENGVLTKFEIFYHISKQS---------
---GTNRSTEDWMSASV---TPPVMSFQLEAVSPGCTVAFQVRVFTSKGPGPFSDIVMSK
TSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSPEGDVSTVGYT----ADDEMGYF----
AQGDALFLLNVRNHSS---SKLFQDALVSDIR-VIAVDWIARHLYFALKASQNGTQIFDV
DLEHKVKSPREVK--ACKGHTTIISFSIYPLLS--RLYWTEVSDLGHQMFYCNISNHTTQ
HVLQPKASN-QHGRSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKK-QEIWAMDLEGCQ
CWKVIMVPAI-P-GKRIISLTVDGEFIYWIMKTKDDAQIYQARKGSGAILSQVKASRSKH
ILAYSSALQPFPDKAYLSLASDMVEATILNATNTSLTLKLPPVKTNLTW-HGITSPTSTY
LIYYMEANKA-KSSD---RKHKM-----LESQENVAQIEGLQPFSMYVIQIAVKNYYSEP
LEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSY
LAPIPETPLRQGEFPSARLSLLVTKLSGGQLYVMK--VLACHPEEMWCTESHPVSVNMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2247)

TPEKPSALVPENTSLQLDWKAPSNVNLTRFWFELQKWKY--NEFYHVKASCS-QGPVYVC
NITDLQPYTSYN-IRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSIPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWDKAEDNGSRLM----YYTLEI--RKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNL
KGTFQFRAVAANEIGLGEYSEISKDITLV--EDGVWITETSF--ILTIIV--GIFLVATV
PLTFVWHRSLKSHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIEN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTF-HGPSLTLLD
LVELCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQDQLQL-FRN
VSLNNVSHCGEAAPISGVINKGFEGEDDE-MVALNSD-DTMPVALMETKNQEGLNYMVLA
TKCSQGEGSYEGPLGPKEPGSCDL-KKDKKQSQADKGFCQEPRVAFGS-PGQSEGLNYAC
LAHSGHGDVSE-

------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MWCTESHRITVKMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2248)

SPERPRAVALEDTSLQLRWKAPSNGNLIRFWFELQKGKY--SEFSHIEASCS-QGPAYVC
NISDLQPYTSYS-VRVVVQ-YETGDRS

ENSGT00760000118818_6_Linker_7_9 (2248, 2471)

PSRSESFWT----RAGVPSKPGIPKLLEGSKNA
IQWEKAEDNGSSLM----YYLLEI--RKITSNDSQNQDLRWKMAFNGSCSSICMWKSKNL
KGMFQFRVVAVNLVGFGDYSGVSDGIILVG--DDLWIPETSF--ILTTII--GVFLVIII
PFAFVWHKGLKNLKTSKEGLTVPMHEDQELEELRGPAAGVGLANACYAVHTLPTQEEIEK
LPAFPRERLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRILLGSGAFGEVYEGMAMDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFDHPNILKQLGVCLFNEPQYLILELMEGGDLLTYLRKARMTMF-HGTLLTLAD
LVDVCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRTVKIGDFG--LARDIYK
HDYYRKRGEGLLPVRWMAPESLMDGLFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQAGGRLAPPRNCPDDLWNLMAQCWAQEPDQRPTFHRIRVQLQL-FRK
LLVNNISPWRGEANTHGATNEGIEGDNDN-MISLNSD-GVTPVAFMETKNQEGLNYMVLA
TEHSQSEDNSEGPLCSKEFESCGL-RKREKEPEVDQDFWQEKQVACCL-PGNSTGLNYAC
LTHSGSGDGSDS

MKNIYRLFLKL-----VIFVTLGC-LWISVLQCTVLNSCLKSCVTNLXXXXXXXXXXX--
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXX---XXXXXXXXXXXXXX
XXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAVSDLSYVVKSLH
PFTEYVFRVVWIYTAQLQLYSPPSPSYRTH-P------YGV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPFIKNIESASPDTVE
VSWAPPQFPGGPVLGYNLRLVSRNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESSITT-SSPAVQEEEQWLFLSRKTSLRKRSLKHVVDEAHCLQ----SDAVHSN
I---TGISVNIHQHTV-----YFSEGTFIWMKKAVNMSDVSDLSAF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGPGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------KMYFIMDELVYVCDLESCSNVKEITPSSI
IAPKKIVVDSYNGYVFYLLRDGIYRVDLPVSP---GQDSEAVRVVESCTLKDFAV----K
PQA----KRIIFFNNTAQGFMSTFLDGSASYFVLPQVLFA-DVKSFACENNDFLVTDGKA
VFHQ-----DSLSFYQFIVGCDLSH----IEEFGFGNLVIFGSSTQPHPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGRPQQLSVL
FGSHQALVQWKSPDLAIGANVI----------LVSNV--VLFLGPAAWQNWTYEVKVSNQ
DFPEITHVFSNISGSMLNVPELQSATKYSVSVRASSPKGPGPWSEPSVG--TTLMPX---
------XXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXMDWYNNSLYYSDAK
GDVYVWLLNGT-EISENHHIPNIAGAGALAFEWLGHFLYWAGKTYVXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXX--X
XXXXXXX-----------XXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX--X-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
FLASG--------QHPLPAFTVEGWKPYTLFNLSVTPYTYWGKGPKTSLSLRTPET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRIFILPSGKYSHKSETVKVEFRWNKPKHENGLLTRFEIFYQISNQS---------
---NINKTYEDWIAVTV---TPSEFSFRLEDLNPRHTVAFKVRVFTSKGPGPFSDIAKSQ
TSEINPFPYLMTLFSNKIVLLDMDQNQAVWTFLAEREISAMGYT----ADNAMGYY----
TQGDSLFILNMRDKSS---SEIFRNAAYFMVTVSIAIDWISRHLYFMLEESQNWMQVLDV
DLELKVKYPRMLK--LCSRNSTIISFSVYPFLS--RLYWTEVSNFGCQMSYYSISNQTLH
HILPPVTPHHATGENLRSCNVSEFELSGEMTLDTSDIKKPRIYFVKG-KEIWITDLEGYQ
CWQVVVEPTLL-AGRTLTSLTVDGVFLYWIATAQDSAQIYQARKSSGTILSQVKALQSKQ
ILAYSSVLQSFPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXXX---XXXXX-----XEFQESVALVEGLQPFSTYIIQIAVKNYYSDP
MEQLPLGKEIWGKTKNGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGRY--NEFCHVKASCS-QGPISVC
TITELQPSTSYG-VRVVVV-YRTGENSTSLPESFKT----KAGVPSKPGIPKLLVGNKNS
IQWERAEDNGSPLL----YYILEF-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXX--XXXXXXXX
XXXXXWHRRIKKKTAPKEGLTVFINEDKELNELRGRAAGVGLANACYAVHTLPTQEEIES
LPVFPREK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2756)

LTLRLLLGSGAFGEVYEGTAIDILGVGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTKF-HGPLLTLTD
LVDLCVDISKGCVYLEQLHFIHR-DLAARNCLVSVKDYSSPSRIVKIGDFG--LARDVYK
NDYYRKRGEGLLPVRWMAPESLVDGIFTTQS----------DVW-FGXXTWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTHCWAQEPDQRPTFHRIQDQLQL-FRN
VSLNSLSQSRQEESITGVINEGFE------------------------------------
------------------------------------------------------------
------------

MKNIYWLILKL-----VNFATLGC-IWISAVQCTVLNSCLKSCVMNMGRQLDSGTPHN--
-LSEPCIQGCHFWNSVDQESCALKCNDTYAAVC--ERESCEVGCSSAEGAYEEEVLENAD
F

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGVTLRWKSANISGVKYIIQWKYAQLPGSWTYTEAVSELSYMVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIFTAQLQLYSPPSPTYRTH-P------SGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNKKLDSGTQRTSFQFYSTLPNTTYR---FFITAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAEANITT-SSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLH----SGATHHN
I---TGISVHVHEQVV-----YFSEGTRIW------------------------------
-------------------------------------V-----K------K-----A---
--A------N-----M-----S------D-----V-----S------D-----L-----R
-----I------F-----Y-----G------G-----S-----G-----L------I---
--S-----S------I-----S-----I-----D------W-----L-----Y------Q
-----R-----M------Y-----F-----------------------------------
-----------------------------------IMGEQVCVCDLENCSNIEEITPPSI
IAPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---GRHSEAMHIVESCTLKDFVV----K
PHS----KRIIYFNDTAKGFMSTFLDGSASHLVLPHVPFA-DVKSFACENNDFLVTDGKA
VFQQ-----DLLSFNEFIVGCDLSH----IEEFGFGNLVIFGSYTQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQQLSVL
FGSHQALVQWKPPALAIGAS------------------------PSAWQNWTYEVKVSTQ
DFPEITHVFSNVSGTMLNVPELQSATKYKVSVRASSPTGPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVYVWLLNGT-DISENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGENPLVLQAKPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-VGNPIIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPRVIPDSVQESSFRIEGNASSFQILWNAPPAVDWGVIFYSVEFSAPSK
FLASE--------QQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLQAPET-VPS
APENPRIFILPSGKYHDK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1614)

NE-VVVEFRWNKPKHENGALTGFEIFYQISNQS---------
---DENKTFEDWISVNV---TPSVMSFQLEAMSPGYTVAFQVRVFTSKGPGPFSDIVKSK
TSEINPFPYLIILFGNKIVLSDMDQNQDVWKFSAERDISAMGYT----ADDAMGYY----
AQGDSLFLLNMHNLST---SEIFRDALVFDIT-IITIDWISRHLYFVLKESQNGMQIFDV
DLEHKVKYPRKLK--ICKGNSTIISFSVYPFLS--RLYWTEVSDFGSQMFYYSIINQTFH
RILQPVATNHPDERGQCSCNVTEFELSGAMTIDTSDLKNPQIYFVKG-QEIWAMDLEGCQ
CWQVIVMPALL--GQMFVSLTVDGEFIYWIATAKDSTQIYQAKKSNGAILSRGQALRSKH
ILAYSSVLQPFPDRAFLSLASDIAEPTILNATNTSLTIRLPPARTNLTE-YAITSPTPTY
LVYYKEVNGRENSSE---LKYRM-----LEFQESIALIEGLQPFSTYVIQIAVKNYYSDP
LEQLPRGKEILGKTKSGVPEAVWPVNTTVRSDTSLLVSWGESCKPNGPKESVRYQLAISH
LGLIPKTPLRQSEYANGRLAVLVTSLSGGKLYMLK--VLACHAEEMWCAESHLVTVETFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2245)

PEKPYALVPGNTSLQLDWKAPSNVNLTRFWFELQKWKY--NEFYNVKASCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YKTG

ENSGT00760000118818_6_Linker_7_9 (2245, 2474)

ENSISLPESFKT----KAGVPSKPGIPKLLDGSKNS
IQWEKADDNGSRLM----YYILEV--RKGTSNDSQKQNLMWTMAFNGSCSSICTWKSKNL
KGTFQFRVVAANTLGFGEYSGISENIPLAG--DGFWIPETSF--ILTIII--GIFLVFII
PLTFVWHRRLKKLKTPKEGLTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIES
LPAFPREKLTLRL

PF00069 // ENSGT00760000118818_6_Domain_9 (2474, 2752)

LLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILRQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTAF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYSNPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLVDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLHYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHKIQEQLQL-FRN
LSLNNISHCREEANPTGVINEGFEDEDGN-VISLTSD-DNRSIALMETKNQEGLNYMVLA
TECSQGEENSEGPLGSKESESCGL-RKEEKEPHADKDICQEKQVAYCP-PGKPEGLNYAC
LTHSGYGDGSD-

MKSVCWLTLKP-----VNFVVLGCIIWISVAQGTVLSSCLTSCVTSLGRQLDSGTQYN--
-LSEACIHGCQFWNSVDQEKCALKCR-----------ESCEVGCSNSEGSYEEEVLESTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGVTLRWNPANISGVKYIIQWKYAQLPGSWTYTETVPKLSYTVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APLILNMESWSPDTVE
VSWVPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESNITT-PSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIHHN
I---TGISVYAQQQVV-----YFSEGTVIWMKGAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YQGSGLVSSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVYVCDLKNCSNLEEITPLSL
IAPQKVVVDSYNGYVFYLLRDGIYRVNLPLPS---GRDTKAVRIVESGTLKDFAV----K
PQS----KRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLV-NVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSVQSYPLPGHPQEVSVL
FGSREALIQWKPPVLAIGA------------------------SPSAWQNWTYEVKVYSQ
DILETTQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWS-GGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSK
FLVIE--------QQSLPIFTVERLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPES-VPS
APENPRIFILSSGRYTKKNE-VVVEFRWNKPKHENGVLTKFEIFYHISKQS---------
---GTNRSSEGWMSASV---TPPVMSFQLEAVSPGYTVAFQVRVFTSKGPGPFSDIVMSK
TSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSPEGDVSTVGYT----TDDEMGYF----
AQGDSLFLLNLRNHSS---SKLFQDALVSDIR-VIAVDWIARHLYFALKASQNGTQIFNV
DLEHKVKSPREVK--TCKGHTTIISFSIYPLLS--RLYWTEVSDLGHQMFYCNISNHTSQ
HVLQPKASN-QHGRSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKR-QEIWAMDLEGCQ
CWKVIMVPAI-P-GKRIISLTVDGEFIYWIMKTKNDAQIYQAKKGSGAILSQVKASRSKH
ILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTW-HGITHPTSTY
LIYYMEANRA-NSSD---RRHKM-----LESQENVARIEGLKPFSMYVIQIAVKNYYSEP
LEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHQPNGPKESVRYQLVMSY
LAPIPETPLRQGEFPSARLSLLVTKLSGGQLYVMK--VLACHPEEMWCTESHPVSVNMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2247)

PEKPSALIPGNTSLQFDWKAPSNVNLTGFWFELQKWKY--NEFYHVKASCS-QGPVYVC
NITDLQPYTSYN-IRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSIPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSRLM----YYTLEV--RKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNL
KGTFQFRAVAANEIGLGEYSEISEDITIV--EDGVWITETGF--ILTIIV--GIVLVATV
PLTFVWHRSLKNHKASKEGLLVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIDN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAIDILGMGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTF-HGPSLTLVD
LVELCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQDQLQL-FRN
VFLNNVSHCGEAAPTGGVINKGFEGEDDE-MVTLNSD-DTMPVALMETKNQEGLNYMVLA
TKCSQGEGSYEGPLGPKELGSCDL-KKDKKQSQADKDFFQEPQVAYGS-PGLSEGLNYAC
LAHSEHGDVSE-

MKSKGGLTPKP-----LHAVILGC-VWVSAVQCTVLSSCLTSCVSNLGRQLDTGTPYN--
-LSEACIQGCQFWNSEDQETCALKCNDTYATLC--ERESCEVGCSTAEGTYEEEVLESTE
F

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PSA-PFASSIGSHSVTLRWNPANISGVKYIIQWKYDQLPGSWTYTETVSKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIMKIESSSPDTVE
VSWAPPHFPGGPVLGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 954)

EAVSVITT-PCPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDTIHHN
I---TGIAVDVQQQVV-----YFSEGTLIWMKKAANMSDMSDLRTF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGVISSISIDWLYR----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVYVCDLENCSNFEEITLLSI
VAPQKIVVDSYNGYVFYLLRDGIYRVSLPLPS---GRHAEAVHIVESGTLKDFAV----K
PQS----KRIIYFNDTMQVFMSTFLDGSAFHRVLPWVPLK-DVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSIQSYPLPGH

PF00041 // ENSGT00760000118818_6_Domain_2 (954, 1064)

PQELSVL
FGSQEALVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DLPKVTQVFSNLSGTILNVPKLQSATKYMVSVRASSPKGPGPWSDPSVG--TTLVP----
--------D--PYFLTNSYADTILYGHQCDYSSCFFLLA--RMRINMDWYNNSLYYSDTT
GNVYVRPLNAM-DISESYHIPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
AHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGRSRAGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIIIAQEIGQRTSVSVSEPAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSVPESSFRIEGHASNFQILWNEPPAVDWGIVFYSVEFSAQSK
FLAIE--------QQSLPMFTVEGMEPYALFNLSVTPYTYWGKGQKTSVSLRAPES-VPS
EPENPRIFILSCGRHVNKEE-VVVEFRWNKPKHENGVLTKFEIVYHTSKQS---------
---DTNKTTEDWISVNV---MPPVMSFQLEAMTPGYIVAFQVRVFTSKGPGPFSNVVMSK
TSEIKPFPYLISLLSNKIMFLDMDQNQVVWTFSTEGDISTVGYT----ADDEMGYF----
VQGDSLFLLNLHNRSS---SKLLQDALLSGVA-VTSVDWIARRLYCARKTSQGGTQIFHI
DLEHKVKSPRDLK--ICKRHSTIVSFSMYALLS--RLYWTEVSDLGHQMFYCSIKNHTLH
HILQPKASN-QRGRRQCSCNVTESELGGAMTVDTSEPKRPWIYFTKG-QGIWAMDLEGCQ
CWKVTMVPHI-L-GNRIVSLTVDREFVYWIITTKDNTQIYQAEKGSGGVVSQVKAPGSKH
ILAYSSALQPLPDKAYLSLASDMVEATILNATNTSLTLKLSPAKTNLTW-HDITSPTPTY
LVYYTEANRT-NSHN---RKHRI-----LESQENIARIEGLQPFSAYVIQVAVKNYYSDP
LGHLPLGKEIQGKTTSGVPGAVCHINSTVLSDTSLHVIWTESDRPNGPQESVRYQLLMSH
LAPIPETPLRQDEFPSARLALLVTKLSGGQLYVLK--VLACHSEEMWCTESHPVTVNMFD
TPEKPSTLVPDNTSLQLNWKAPSNVNLTRFWFELQKWKY--NEFYHVEASCS-QGLVYVC
NIADLQPYTPYN-VRVVVV-YMTGENSSSSPESFKT----KAGVPSKPGVPKLLEGSKNS
IQWERAEDNGSRLM----YYILEI--RKGISNDSQNQSLRWKMVFNGSCNSICTWKSKNL
RGTFQFRAVAANNIGFGEYSGISEDITLV--EDGFWITETSF--ILAVIV--GIFLVASL
PLTFVWYRGLKTRKAPKEGLSVLNEDDKELAELRGLAAGVGLANACYAVHTLPTQEEIEN
LPTFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2673)

RLLLGSGAFGEVYEGTAVDILGVGSGETKVAVKVMCI------------
--SELYHFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTF-HGPLLTLVD
LVEVCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDV--------CTLH---------------
----LKLEVLT--------------YFCQWNLMSQCWAQEPDQRPTFHNIQDQLQL-FRN
VSLNNVSQCGEEAHASGVINKGFEGKLDSSVFPPQWD-RARL----Q-------GRRKPP
KECCHGNPKYSVPLVKEGVGECCRISQTSRGTHASYG-----------------------
------------

MKRIRWLTPKP-----ATFVVLGC-VWISVAQGTILSSCLTSCVTNLGRQLDSGTRYN--
-LSEACIQGCQFWNSIDQEKCALKCNDTYVTIC--ERESCEVGCSNAEGSYEEEVLDNTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSNGVTLRWNPANISGVKYIIQWKYAQLPGSWAYTETVSKLSYMVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFITNIESSSPDTVE
VSWAPPYFPGGPILGYNLRLISKTQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESMITT-PSPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIRHN
I---TGISVNTQQEVV-----YFSEGTIIWMKGAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSALVSSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDNRVHVCDLKHCSNLEEITPFSI
VAPQKVVVDSYNGYVFYLLRDGIYRVHLPLPS---VRDTKAVRIVESGTLKDFAV----K
PQS----KRIIYFNGTMQVFMSTFLDGSAFHRVLPWVPLA-DVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSVQSYPLPGHPQEVSVL
FGSREALIQWKPPILAIGA------------------------SPSAWQNWTYEVKVSSQ
DILETTQVFLNISRTVLNVPKLQSSTKYMVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DISENYHISSIAGACALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDPVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWS-GADATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPGKFNQFTIIQTSL
KPLP--GNFSSTPTVIPDSVQESSFRIEGHTSSFRILWNEPPAVDWGIVFYSVEFSAHSK
FLAIE--------QQSLPVFTVEGLEPYALFNLSVTPYTYWGKGQKTSLSFRAPES-VPS
APENPRIFILSLGRYTRKNE-VVVEFRWNKPKHENGVLTKSEIFYHISKQS---------
---GTNKSTEDWVSVSV---TPPVMSFQLEAMSPGYIVSFQVRVFTSKGPGPFSDIVMSK
TSEIKPCPYLISLLGNKIEFLDMDQNQVVWTFSLEGAVSTVGYT----ADDEMGYF----
AQGDALFLLNLHNHSS---SKLFQDVLASDIA-VIAVDWIARHLYFALKASQDGTQIFDV
DLEHKVKSPREVK--ICKSHTAIISFSMYPLLS--RLYWTEVSDLGYQMFYCNISSHTLH
HVLQPKASN-QHGRRQCSCNVTESELSGAMTVDTSDPDRPWIYFTKQ-QEIWAMDLEGCQ
CWKVIMVPAT-P-GKRIISLTVDGEFIYWITTMKDDTEIYQAKKGSGAILSQVKAPRSKH
ILAYSSALQPFPDKAYLSVASNMVEASILNATNTSLILKLPPVKTNLTW-HGITTPTSTY
LVYYMEANRA-NSSD---RKHNM-----LESQENVARIEGLQPFSTYVIQIAVKNYYSDP
LEHLSLGKEIQGKTKSGVPGAVCHINATVLSDTSLLVFWTESHKPNGPKELVRYQLVMSY
LAPIPETPLRQDEFPSARLSLLVTKLSGGQQYVLK--ILACHSEEMWCTESHPVSVNMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2247)

TPEKPSALVPENTSLLLDWKAPSNANLTRFWFELQKWKY--SEFYHVKASCS-QGPVYVC
NIANLQPYTPYN-IRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSIPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGNRLM----YYTLEV--RKSISNDSRDQSLRWTAVFNGSCSSICTWRSKNL
KGTFQFRAVASNAIGFGEYSEISEDITLV--EDGFWITETSF--ILTIIV--GIFLVATV
PLTFVWHRSLKNHKATKEGLSVLNDNDQELAELRGLAAGVGLANACYAVHTLPTQEEIES
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAVDILGRGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTL-SGPLLTLAD
LVELCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
HDYYRKRGEGLLPVRWMAPENLMDGIFTSQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQL-FRN
VSLNNVSHCGQAAPAGGVINKGFEGEDNE-MATLNSD-DTMPVALMETRNQEGLNYMVLA
TKCSQSEDRYEGPLGSKESGLHDL-KKDERQ-PADKDFCQQPQVAYGS-PGHSEGLNYAC
LAHSGHGDVSE-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RS-SGEPHIT
EFAAWSTSEISQNTLMYYSGRLFWINGFRIITAQEIGQRASVSVLEPARFNQFTIIQPSL
KPLP--GNFSVTPKVIPDTVQESSFRIEGNASSFQILWNAPPAVDWGVIFYSVEFSSHSK
LLASE--------QQLLPVFTVEGLEPYAFFNLSVTPYTYWGKGPKTSLSLRAPET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APQNPRIFVLPSGKYHNQKE-VVVEFRWNKPKHENGVLTRFEILYRISNQT---------
---DTNETFEDWITVNA---APSEMSFQLEGMSPGYTIAFQVRVFTSKGPGPFSDIVKSK
TSEINPFPYLITLFDSKIVLLDMDQNQIVWTFSTERDINSVGYT----ADDGMGYY----
AQGDSLCLLNMHNRST---SEIFRDALVFDVT-IIAVDWISRHLYFVRKASQNGMQIFDV
DLEHKVKYPRKLK--ICNRNSTIVSFSVYPLLS--RLYWTEVSDFGSQMFYYSIINETLS
HILPPIATNHSNGRRQCFCGVTQFEFNGTMTVDTSDLKKPQIYFVKG-QEIWAMDLEGCQ
CWQVIILPGFSRAGKTLESLTVDGEFLYWIFSAKDSTQIYQAKKSNGAILSQVKAQRSKR
ILAYSSALQPFPDKALLRLASDIAEPIILNTTNTSLTIRLPPTRTNLSW-PGFTSPTPTY
LVYYKEVNGRKTSSE---LKYKM-----LEFQDSVVLIDGLQPFSTYVIQTAVKNYYSDP
VERLPLGKEIWGKTKTGVPEAVRLINATVHSDTSLLVSWRESHKPNGPKESVRYQLVISH
LALIPETPLRQSEYPNGRLALLVTRLSGGKLYVLKEKVLACHAEELWCAESHPVTVHM

PF00041 // ENSGT00760000118818_6_Domain_7 (2159, 2253)

FD
TPERPFSLVPGNTSLQLDWKAPSDVHLIRFWFELQKGKD--NEFSRVNTSCV-HGPAYVC
NITDLQAYTRYA-VRVVVV-YRTGENSTSLPE

ENSGT00760000118818_6_Linker_7_9 (2253, 2469)

SFKT----QAGVPSKPGIPKVLEGSKDS
IQWEKAEDNGSRLL----YYVLEI-SRTGISNDSQNQNLKWKMAFNGSCSSICTWKSKNL
KGTFQFRVVAANNLGFGDYSGISENIILVG-VDGFWIPETSF--VLTIII--GIFLVVTI
PVVFVWHRKLKNQKTPKEGLTGLINEDKELAELRGLAVGVGLANACYAVHTLPTQEEIER
LPAFPREK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LTLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSRFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLAD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSMKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKTGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPTHSNLDVLNYVQTGGRLEPPRNCPDDLWNLLTQCWAQEPDQRPTFHKIQDQLEL-FRN
VSLNSISQCREEADPSGIINEGFEDEDGG-VICLNSG-DVMPIALTETKNQEGLNYMVLA
TGCSQGKENSEGPLGSKESESCGL-RKEEKQPHADKDVCQEKQVAYCP-PGKTEGLNYAR
LTHSGYRDGSD-

MKNSYWLILKL-----VNFVTLGC-LWISVSQCTVLNSCLKSCVTNLGRHLDSGTPYN--
-LSEPCIQGCHFWNSADQEKCAFKCNDTYATIC--ERESCEVGCSSSEGAYEEEVLEN

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

VD
LPTA-PFASSIGNQSVTLRWKSANISGIKYIIQWKYAQHPGSWTYTEAVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPP

ENSGT00760000118818_6_Linker_0_1 (204, 218)

SPSYRTH-P-----

PF00041 // ENSGT00760000118818_6_Domain_1 (218, 306)

-YGAPETAPLIRNIESSSPDTVA
VSWAPPQFPCGPILGYNLRLISKNQKLHSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AGSSITT-SSPAVQEEEQWLFLSRKSSLRKRSLKHLVDEAQCLQ----SDAAHHN
I---TGISVHVQRQVV-----YFSEGTLIW------------------------------
-------------------------------------A-----K------E-----A---
--S------N-----M-----S------D-----V-----S------D-----L-----R
-----I------V-----Y-----R------G-----S-----G-----L------I---
--T-----S------I-----S-----I-----D------W-----L-----Y------Q
-----R-----M------Y-----F-----------------------------------
-----------------------------------IMDELVYVCDLENCSNIEEITPPSV
IAPQKIVADSYNGYVFYLLRDGIYRVALQVPP---GRDSEAMRIVESCTLKDFAV----K
PQS----KRIIYFNDTTQVFMSTFLDGSASHLVLPHVPFA-DVKSFDFENNHFLVTDGKA
VFQQ-----DALSFNEFIVGCDLRH----IEEFGFGNLVMFSRYTQPYPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PARPQQLSVL
FGSYQALVQWKPPALAIGAS------------------------PSSWQNWTYEVKISTQ
DFPGNTRVFSNIRGTVLNVPGLQSATQYEVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIKNVSDMDWYNNRLYYSDMK
GDVHVWLLNGT-NISKNDHIPNIAGAGALAYEWLGHFLYWAGRTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESPLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYRAVLRGQG-VGEPTIT
EFAAWSTSDISQNALMYYSGRLFWINGFKIITAQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWHAVPAVDWGAIFYSVEFSAPLK
FLASE--------KQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRIFILSSGKYHNKNE-VVVEFRWNKPKHENGVLTRFEIFYQISNQS---------
---ATNKTFEDWIAVNV---TPSVMSFQLEGMSPGYIVECEVRVFTSKGPGPF

ENSGT00760000118818_6_Linker_4_5 (1614, 1940)

SDLVQSQ
TSEVNPFPRLITLLGNKMILLDMDQNQVVWMFSAERDISAMGYT----ADDAMAYY----
AQGDSLFLLNMHNQSS---SEIFQDALVFDIT-IITIDWISRHLYFVMKESQNGMQIFDV
DLEHKVKYPRKLK--ICNRNSTIISFFVYPLLS-SRLYWTEVSDLGSQMFYYSIINQTLH
RILQPTATSHPNGRSQCSCNVTESELSGVMTIDTAHLKKPQIYFVKG-QEIWATDLEGCQ
CWQVITRPALLETGKTLVSLTVDGEYLYWVSAAKDGTEIYQVKKCRGAIPSQVKAPRSER
ILAYSSVLQPFPDKAFLSL

PF00041 // ENSGT00760000118818_6_Domain_5 (1940, 2038)

ASDIAEPIILNTTNTSLTIRLPSSRTNLTW-YGITSPTPTY
LVYYKEVNDGKNGSE---PKYRM-----LEFQESIALIEGLQPFSTYMIQIAVRNYY

ENSGT00760000118818_6_Linker_5_6 (2038, 2059)

SDP
LEQLPLGKEIWGKTKSGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2151)

PEAVWLINTTVQSDTSLVISWRESPKPNGPKESVRYQLAIAH
LARVPETPLRQSEYPHGKLALLVTGLSGGKLYVLK--VLACHAEEMWCAE

ENSGT00760000118818_6_Linker_6_7 (2151, 2159)

SHPVTVEM

PF00041 // ENSGT00760000118818_6_Domain_7 (2159, 2247)

FD
TPEKPYALVPGNTSLQLDWEAPSNVNLIRFWFELQKWKY--SEFYHVKASCS-QGPAYVC
NITDLQPYTSYH-VRVVVV-YRTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2469)

STSLSESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKADDNGSRLI----YYIIKI-NNISQYN-ILKNKIKWKMAFNGSCSSICTWKSKNL
KGTFQFRVVAANNLGFGEYSGISENILLAG-VDGFWIPETSF--ILTVVI--GIFLVVII
PLTFVWHRRLKNQKTPKEGLTVLINEDKELAELRGLAAAVGLAHGCCAIRTLPTQEEIES
LPAFPRAN

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2756)

LTLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAYLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQLHFIHRLNIAARNCLVSVKDYSNPSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQSGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHKIQDQLQL-FRK
ISLNSISQCREEADPGGVINEGFDDEDGN-MVCVNLD-DSVPIALMETKNQEGLNYMVLA
TECSQGEDHSEGPLGSKESESCGL-RKEEKEPHADKGIRQEKHVAYCP-PGKPEGLNYAC
LTHSGHGDGSD-

MKNIYWLILKL-----ADFATLGC-LWISVVQCTVLNSCLKSCVTNLGRQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKC-----------WESCEVGCSSAEGAYEEEVLENAG
LPTA-PFASSIGSYNMTLRWKSANFSGVKYIIQWKYAQFLGSWTYTKTVSKLSYVVEALH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIG

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKHQKLDAGTQRTSFQFYSTLPNTVYR---FSIAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTFIWVKKATNMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLKNCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRVDLPVPS---GQCAEAVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHIILPHIPIA-DVKSFACENNDFLVTNGKV
VFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQPHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIVELFELGPSAWQNWTYEVKVSTQ
DHPEVTYISLNVSGTMLNVPELQSATKYKVSVRASSLKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTNVIQRQSMLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VTALALDLSDGLLYWLVQDSQYIHLYTAVLRGQS-AEDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGLRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFHIRWNGPPAVDWGVVFYSVEFSAQSK
FLTSE--------QQSSPVFTMEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENSRIFILPSGKCCN

PF00041 // ENSGT00760000118818_6_Domain_4 (1518, 1614)

KNE-VVVEFRWNKPRHENGVLTRFEIFYKISSQS---------
---ITNKTFEDWIAVNV---TPSVMSFQLEGMTPGCFVAFQVQAFTSKGPGPFSDILKST
TSEIKPFPYLITLLDNKIVFLDMDQNQVVWMFSAERVISAMGYT----ADNEMGYY----
AEGDSLFLLNLHNRSS---SELFRDSLISEIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEDKVKYLREVK--ICNRNSTIISFSVYPLLS--RLYWTEVSDFGYQMFYYSVINHTLH
RILQPTATNQQSKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAADLEGCQ
CWRVITVPAMLA-GKTLISLTVDGDFVYWIITAKDNTQIYQAKKGNGAIVSQVNALRSKH
ILAYSSIMQPFPDRVFLSLASDTVEPIILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQGSIALIEDLQPFSTYMIQITIKNYYSDP
LEHLPPRKEIWGKTKSGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAILH
LALIPETPVRQGEFPNGSLTLLVTRLSGGNIYVLKV--LACHSEEMWCTESHPVTVEMFD
TPEKPYPLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWFELQKWKY--NEFYHVKTSCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLSESFIT----KAGVPSKPGIPKSLEGNKNS
IQWEKAEDNGSRII----YYILEI--RKGTSNNSQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISGNIILVG-D-DFWIPETSF--ILTIIV--GIFLIVTI
SLTFAWHRRLKNQKSAREGPTVLINEDQELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSRFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LIDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTHS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTNGVINEGFEGEDGN-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECSQGKEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LTHSGYGDGSD-

MKNISWLGPKL-----VSFVSLGC-IWISVVQCTVLNSCLKSCVTNLGRQLDIGMPYN--
-LSEPMYQRKQFL----------GCTDW--------YESCEVGCSGAEGAYEEEVLENAG
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWKSANISGVKYIIQWKYAQLPGSWTYTEAVSKLSYTVESLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWILTAQLQLSSLPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APSIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQQLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESSITT-PSSAVQEEEQWLFLSRKSSLRKRSLKHLVDEAHCLH----SDAIYSN
I---TGIAINVHQQVV-----YFSEGTLIWVKQVANMSDVS-------------------
------------------------------------------------------------
-----------------------------------------------D-----L-----R
-----I------F-----Y-----K------G-----S-----G-----L----------
---------------------------------ISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDERVYTCDLENCSNTEEITPPSI
TTPQKIVADSYNGYAFYLLKDGIYRVDLPVPS---GRDSEALRIVESCTLKDFAV----K
PQS----KRIIYFNDTARVFMSTFLDGSASHPVLAHVSFA-DVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSNAQPHPMPGRPQQLSVL
FGSHQALVQWKPPALAIGANEFTGNFLFAL-------VYVILVSPSAWQNWTYEVKVSTE
DFPEITRIFSNISGTVLNVPELQSAARYKVSVRAGSPKGPGPWSEPLVG--TTLVP----
--------ASEPPFIMALKEDGLWRMPLNSFGPGEFLSSDTGNVSDMDWYNNSLYYSDTK
GDVHVWLLNGT-DISENYRIPNIAGAGALAFDWLGQFLYWAGRTYVIQRQSLLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTLHSVESTRLNGESSLVIQAQPWFSGKK----------
------------------VVALTLDLSDGLLYWLVQDSQCIHLYTAVLRGRS-AGDINIT
EFAAWSTSEISQNTLMYYSGRLFWINGFRVITAQEISQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSVTPKVIPDSVQESSFRIEGNASSFQILWNAPPAVDWGIIFYSVDFSSHSK
FLASE--------QQLSPVFTVEGLEPYALFNLSVTPYTYWGKGPQTSLSLRAPET-VPS
APQNPRIFILPSGKYH

PF00041 // ENSGT00760000118818_6_Domain_4 (1517, 1614)

NQNE-VVVEFRWNKPTHENGVLTRFEMFYQISSQR---------
---DTHKTFEDWMAVNA---TPSEMSFQLEGMSPGYTVAFQVRAFTSKGPGPFSDTVNSR
TSEINPFPYLMTLFDSKIVLLDMDQNHVVWTFSAEGDISTMGYT----ADNGMGYY----
AQGDSLCLLNMHNRSS---SEIFRDALVFDIT-IITIDWISRHLYFVLEESQNGMQIFDV
DLEHKVKYPRKLD--ICNRNSTIISFSVYPFLS--RLYWTEVSDLGPQMFYYSIINQTLS
HILPPTATNHSNGRKQCFCSITQFEFSGAMTIDTSDLERPQIYFVKG-QEIWAMDLEGCR
CWRVIMVPTLL-AGEMLESLTVDGEFLYWISSAKDSTQIYQAKKSNGAILSQVKAQGSKH
ILAYSSVLQPFPDKALLCLASDVAEPTILNTTNSSLTIRLPPTRANLAW-HSITCPTPTY
LVYYQEVNGGKNSSG---LKYKM-----LEFQERIACIEGLQPFSTYVIQTAVKNYYSDA
VEQLPLGKEIWGKTRSGVPEAVRLINTTVQSDTRLLVSWEESHKPNGPMESVRYQLEISH
LALIPETPLRQSEYPNGKLSLLVTRLSGGKPYVLK--VLACHAEEMWCAESHPVTVKMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2246)

PEKPCALVPENTSLQLEWKAPSNVNLIRFWFELQKWKY--NEFYRVNTSCI-QGPTYVC
SITDLQPYMSYN-IRVVVV-YRTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPSKPGIPKLLEGSKDS
IQWEKAEDNGSRNNTYIVSYIFYI-DHFGTSNDSQNQNLMWKMAYNGSCGSICTWKSKNL
KGTFQFRVVAANNLGFGDYSGISENIILVG--DGFWISERSF--ILIIII--GIFLVVII
SLIFVWHRKLKKQKTPTEGLTGLIHEDKELAELRGLAAGVGLANACYAIHTLPTQEEIES
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTKF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLQPPRNCPDDLWNLLTQCWAQEPDQRPTFHKIQDQLQL-FKN
VSLNSISQRREETDPRGVINEGFEYEDGS-VICLNSG-DVTSVALMETKNQEGLNYMVLA
TECSQGEGNSEGPLGSKESESCGL-RKEEMEPHADKDICQEKQVAYCP-PGKPEGLNYAC
LTHSGYRDGSD-

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCNDTYATIC--ERESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTMYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAETVRIVDSCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPHIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DPPEVTRIFSNISGTRLNVPELQSAMKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWQLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVDV---TPSVMSFQLEDMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIVFLDMDQNQVVWTFSAERVVSAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINCTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFTKA-QEIWAMDLEGCH
CWRVITVPAML-G-KTLASLTVDGDFIYWIITAKDSTRIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-YGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
APEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPGKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

MKNIHWFILKL-----VNFTTLGF-IWISVVQSTVLNNCLKSCVTNLGRQFDIGSPSN--
-LSVPCIQGCHFWNSVDQENCTLMCR-----------ESCDVGCSIAEGAHEDQVLE---
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PSA-PFASSIGSHSVALRWKPANISGVKYIIQWKYAQLPGSWTYTETVSKLSYMVESLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLQLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIYNIESSSPDTVE
VSWAPPQFPAGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNGV
GEGPEAESNITT-SSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLW----SDIIYHN
I---TGISVNVQQETV-----YFSEGFLIWVKEVANMSDMSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNFEEITLPSV
MAPQKVVADSYNGYVFYLLRDGIYRVDLPAPS---GRPAPAVRIVESWTLKDFAI----K
PQS----KRIIYFNNTAQAFMSTFLDGSASHLILPHVPFA-AVKSFACENNDFLVTDGKA
VFQQ-----DSQSFNEFIVGCDLSH----IEEFGFGNLVIFGSSVQPHPLPGRPQELSVL
LGSHQALVQWKPPALAIGASE----------------------CPSAWQNWTYEVKVSTQ
DHPEITQVFSNISGTMLNVPELQSATKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------AIEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMN
GDVYVWPLNGT-DASEYYHIPSITGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTFYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDQLLYWLVQDNQCIHLYTSILRGQS-TEDVHIT
EFAAWSTSEISQNALMYYSGRLFWIDGFSIITAQEISQRTSVSVSEVAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSIQESSFRVEGNGSSFQVLWNPPPVVDWGTVFYSIEFSAHSK
FLATE---------QSLSMFTVEDLQPYALFNLSVTPYTYWGKGPKTSLSFRAPET-VPS
APENPRIFILPSGHKLNHSK-VVVEFRWNKPKHENGVLRIFEIFYHISNQS---------
---DTKKIFQDWTAVNV---TPWDMSFQLASMDPGYIVAFQVRVFTSKGPGPFSDIVKTK
TSDINPLPYLITLADNKVEFLDMDQNQVMWTFSVEGDLSALGYT----ADNHMGYY----
AQGDTIFLLNLHNHSS---SELFQDTLVSDIT-VIAVDWIARHLYFVLKGSQNGTQIFAV
DLEHKVKCPMEVK--TCNTDSTIISFSVYPFLS--RLYWTEISDLGYQMFYCSVINHTLH
RILKSTATIPQNARSQCSCNVTEVELGAAMTVDASNLAEPRIYFTKG-QEIWATDLEGCQ
CWSIVMVPDILV-GKPLDSLTVDGEFIYWTTKAKDSTQIYQAKKRNGAILSQVKTQRSKH
ILAYSLVMQPFPDNAYLTLASDVGEPIILNATNTSLTIRLPPVKTKLTL-HGIISPTPTF
LVYYKEVNDIITSSE---LNYRV-----LESQEDIVLIGGLQPFSTYMIQIAVKNYYSDP
LESLPLGKEVFGKTKRGVPGAVCVINATVLSDTRLLISWRESQKPNGPKDSVRYQLTISH
LAPIPETPLRQSEFPNTQLSLLVTKLSGGQLYVLKV--LACHPEEMWCAESHAVTVKMFN
TPEKPYGLIPDNTSLQFDWMAPPNTNLIRFWFELQQWKH--NEFYHAKASCS-QGPAYVC
NITDLQPYTFYH-VRVVVV-YMTGENSTSLSEGFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGNRIL----YYILEI--RKGISNDAQNHNLRWKMAFNGSCNSICTWKSKNL
KGTFQFRVVAANNLGFGEHSEVSEDIIL-A-EDGFWTAETSF--ILSIIL--GIFLIVTV
PLTFVWLRRAKNQKPSKEALTVLINEDKELSELRGVAAGVGLANACYAIHTLPTQEEIER
LPTFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRVLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKASTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARKSKF-HGPLLNLVD
LVDLCVDISKGCVYLEQLHFIHR-DLAARNCLVSVKDYTRPSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPEQRPTFDKIQEQLQL-FRN
FSLRSIPQCPNEAINGGVINEGFEGEDDN-VISLNSD-DTMPVALVETKNQEGLNYMVLA
TECNQVEERSEGPLGAKESESCGL-RKEEKEPHADEDFCQEKQVACCP-PGKPGGLNYAC
LTHSGYRDASD-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1609)

PS
APENPRVFVLPSEKYHNKNE-VVVEFRWNKPKHENGVLTRFEMFYQLSKES---------
---DTNKTFEDWIVVNV---TPSVMSFQLQGMSPGYTVAFQXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXX----
XXXXXXXXXXXXXXXX---XXIFRDALVFDIT-MITVDWLSRHLYFVLKDLHNGMQIFDL
DLENKVKYPRKLK--ICNRNSTIISFSVYPFLS--RLYWTEVSNFGSQMFYYCIINQTLH
QILQPTAINHPSGRSQCSCNVTELELSGAMTIDTSDLKKPQIYFVKG-QEIWAMDLEGCQ
CWQVTMMPALL-AGKTLVSLTVDGEFLYWIATAKDSTQIYQVKKSNGVILSQVEAPRSKR
ILVYSSVLQPFPDRAFLSLASDIAEPTILNATNTSLTIRLPPARTNLTW-YGITSPTPTY
LVYYKEVNGRKNSSE---LEDRM-----LEFQKSIALIEGLQPFSTYMIQIAVKNYYSDP
LELLPLGKEIWGKTKSGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2151)

PEAVWLISTTVQSDTSLVISWRESPKPNGPKESVRYQVAISH
LAPIPETPLRQSEYPNGRLSLLVTRLSGGKLYVVK--VLACHAEDMWCAE

ENSGT00760000118818_6_Linker_6_7 (2151, 2162)

SRPVTVEMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2253)

PEEPYALVPENTSLQLDWKAPSNVDLIRFWFELQKWKH--NEFYHVTASCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YRTGENSTSLPE

ENSGT00760000118818_6_Linker_7_8 (2253, 2469)

SFKT----KPGVPSKPGIPKLLEGSKNS
IQWEKSDDNGSRLM----YYILEI--RKGTSNDSQKENLMWKVAFNGSCSSICTWKSKNL
KGTFQFRVVAVNNLGFGDYSGISEDIVLVG--DGFWIPETSF--ILTIII--GILLVITI
PLTFVWHRRLKYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLPTQEEIES
LPAFPRER

PF00069 // ENSGT00760000118818_6_Domain_8 (2469, 2563)

LSLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTX-XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXXXXX--XXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXW

PF07714 // ENSGT00760000118818_6_Domain_10 (2731, 2754)

TLMTQCWAQEPDQRPTFHKIQDQLQL-FRN
FSLNGISQCREAAKSSGVINEGFEDEDGH-VICLNSDEV-----TSEAKNQEGLNYMVLA
TEFSQGEANSEGPVDSKESDSRGL-RKEEKEPRADKDICQEKQVAYCP-PGKPEGLNYVC
LTHSGYGDGSD-

MRNACLL---L-----NRLGAFYF-IWISAAYCSFSKNCQDLCTSNLEGELGIANLCNVS
DINVACTQGCQFWNATEQVNCPLKCNKTYTREC--ETVSCKFGCSRAEDAYGVEAQNCLN

PF00041 // ENSGT00760000118818_6_Domain_0 (121, 190)

KPGA-PFASSIGSHNITLGWKPANISEVKYIIQWKFHQLPGDWRYTEVVSETSYTVKDLQ
AFTEYEFRV

ENSGT00760000118818_6_Linker_0_1 (190, 232)

VWIITSQLQLHSPPSPSYRTHA-------SGVPTTAPIIKDI

PF00041 // ENSGT00760000118818_6_Domain_1 (232, 305)

QSSSPNTVE
VSWFPPLFPNGLIVGYNLVLTSENHELLRASRGHSFQFYSTFPNSTYR---FSIVAVNEA
GAGP

ENSGT00760000118818_6_Linker_1_2 (305, 954)

PAEANITTPESKV-KEKAKWLFLSRNQSLRKRYMEHFLEAAHCLQ----NGIIHHN
I---TGISVNVYQQVV-----YFSEGNSIWVKGVVDMSDVSDLTLF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YTGWGNITSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFVMNEKIHVCQLENCTAAEDITPPYV
TSPRKIVADPYNGYIFCLLEDGIYRANLPLFP---DTASAASLVVKSHTLRDFMI----N
FQS----KRLIFFNKTEQAFVSGFLDGSEFHTLRAHVPLD-DMESFVYEDNIFTVTDGRA
VFHEEISQVGSSSFNEYVVDCSLEY----PEYFGFGNLLFYAASTQPYPLPTL

PF00041 // ENSGT00760000118818_6_Domain_2 (954, 1064)

PRLVTVL
FGSDQAVISWSPPEYTIGTS------------------------RSAWQNWTYDVKVSSQ
STFEEEWVVSNITDTRFAVKNLVSFTEYEMSVRAVSPAGEGPWSEPFRG--MTFEE----
--------AEEEPYILAVGAEGLWKQRLDSYGPGEFLYPHIRNISDLDWYNDTLYWSNSM
GKVQTWSMNKKEGTTENSYVPDIKNARMLAFDWLGQCLYWAGKANTIYRKSLLGDHMDVV
AHVVYVVKDLAVDSVNGYLYWATTYTVESARLNGEEYLILQEHLQFSGKQ----------
------------------VVGLALDLTSGFLYWLVQDGLCLNLYRISICKES-CGNIMVT
EISAWSVSEVSQNALQYYSGRLFWINRLKFITTQELNQSISIPFSEPAEFAAFTLVHTSL
KPLP--GNFSFTPKVIPSSVPESSFKIKGNSSSFHIIWNASTDVQWGTVFYCVGSNALQ-
MRTLESERCLHPHDLTVPSYKVDWLEPFTLFDFSVTPYTYWGKAPTTSVYLRAPEG-VPS
APANPRIYVLHSNTHEGEEK-VLVELRWDKPERDNGVLTQFRVYYQLLYES---------
---GAADTLMEWNVSDV---KPTALLFSIRDVHPRLTVRFQVQAFTSVGPGPMSDVAQRN
SSDIFPVPTLITFSSNKLFLTDIDSNHTIWEVLTNRNIKDICYT----ADDDKVYY----
ILEDSLFLLNVQSTSE---SQLFEDVFLRNVT-AITVDWIARHLFVAMKTSWNETQVFFI
DLELKTKSLKALNIQLGKRNSTISSLLSYPFLS--RLYWIEELDYGSRMFYYDILNNTMY
HILGYESVE-EKMRNYCNCNVAEAELGRPISIDVTDIKKPQLLFIRGRDEIWASDVDGCH
CWRITKIPSFQ--GTKIGSLTVDKQFIYWTIEKKEYTEICLADKESTRHSLQRKANHELK
ILAYSSAMQSYPDKKCLTPLLDTEKPTILDTTNTSFTLSLPSVTTQQLC-PSISQPTPTY
LVFFREITSNHENST---YHFSTLLQKTLEIQEPIAVINNLKPFSSYAIQVAVKNYYSNQ
N-QLAVGRETISTTLYGVPEGVDSIKTVVLSDTTINISWSEPLEPNGPLESIRYQISVNL
LSLFPEAPLRKSEFPNGTLSWSVSDLQSGTNNLFK--VLAFHPNENWFSESVPVIAKTFE
TPLSPSNIIPRNTSFQLEWRAPLHINGTSFWFELRKWQTRSDWFSPASTTCT-VGPVYTC
NLTGTLPSANYL-VRATVV-YVTGMKSTSSPTSFKTT----AGVPSKPGTPKRAEDSKNS
VQWEKAEDNGSNLT----YYILESRKQS---GNTNKVKSLWVVVYNGSCDSICTWKAENL
EGTFQFRAAAANMLGLGEYSDTSKDIVLAK--DTVTSPDI--TAIVAVIGAVVLGLTIII
LFGFVWHQRWKSRKPASTGQIVLVKEDKELAQLRGMAETVGLANACYAVSTLPSQAEIES
LPAFPRDK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLK
EAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKF-QSPLLTLTD
LLDICLDICKGCVYLEKMRFIHR-DLAARNCLVSEKQYGSCSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLIDGVFTNHS----------DVWAFGVLVWETLTLGQQP
YPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQE-IRH
SPLCFSYFLGDKESVAGFINQAFE--DID-VPPADSD-SILSTTLMEARDQEGLNYLVVV
KESNQDQGSIS-------SAELTS-V----------------------------------
------------

MKSKGWLALKP-----LNTVILGC-VWVSAVQCTVLSSCLASCVTNLGRPLDIGTPYN--
-LSEACIQGCQFWNSQDQEKCALKCNDTYATIC--ERESCEIGCSTAEGTYEEEVLESTE
F

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWNPANISGVKYIIQWKYDQLPGSWTYTETVPKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRT-HP------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIMKIESSSPDTVE
VSWAPPHFPGGPVLGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 954)

EAESIITT-PSPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDTIHHN
I---TGIAVDVQQQVV-----YFSEGTVIWMKKAANMSDMSDLRAF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YGGSGVISSISIDWLYR----------------
------------------------------------------------------------
-------------------------------RMYFIIDKLVYVCDLENCSNFEEITPLSI
VAPQKVVVDSYNGYVFYLLRDGIYRVSLPLPS---GRHTEAVHIVESSTLKDFAV----K
PQS----KRIIYFNDTVQVFMSTFLDGSAFHQVLPWVPLK-DVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSIQSYPLPGH

PF00041 // ENSGT00760000118818_6_Domain_2 (954, 1064)

PQELSVL
FGSQEALVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DLPQVTQVFSNLSGTMLNVPELQSATKYMVSVRASSPKGPGPWSDPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DASENYHIPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
AHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGRG-AGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSESAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSVQESSFRIEGDTSNFQILWTEPPAVDWGIVFYSVEFSAQSK
FLAIE--------QQSLPMFTVEGLEPYALFNLSVTPYTYWGKGQKTSLSLRTPES-VPS
APENPRIFILSCGRYVNKNE-VVVEFRWSKPKHANGVLTKFEIIYRISEQS---------
---GTNKTTEDWISVNV---IPPVMSFQLEAMSPGYIVAFQVRVFTSKGPGPFSDMVVSK
TSEIKPFPYLISLLGNKIVFLDMDQKKVLWTFSTEGDISTVGYT----ADDEMGYF----
VQGDSLFLLNLHNRSS---SKLLQGALVSDVA-VTAVDWIARRLYFALKTSQDGTQMFDV
DLEHKVKSPRELK--ICKRHSAIISFSVYPLLS--RLYWTEVSDLGHQMFYCSISNHTLH
HIVQPKASS-PHGRRQCFCNVTESELGGAMTADTSEPKRPRIYFTKG-QEIWAMDLEGCQ
CWKVTMAPAI-L-GKRIASLTVDREFVYWIITTKDNTQIYQAEKGSGAVVSQVKAPGSKH
ILAYSSALQPLPDKAYLSLASDMVEATILNATNTSLTLKLPPAKTNLTW-HGITSPTPTY
LVYYTEANNT-NSHN---RKHRI-----LESQETVAHIEDLRPFSAYVIQVAVKNYYSDP
LGHLPLGKEIQGKTTSGVPGAVCHINATVLSDTSLHVIWTESDRPNGPQESVRYQLVMSH
LAPIPETPLRQGEFPSARLALLVTKLSGGQLYVLK--VLACHSEEMWCTESHPVTVNMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2247)

TPEKPSALVPDNSSLRLNWKAPSNVNLTRFWFELQKWKY--NEFYHVEASCS-QGPVYVC
NIADLQPYTPYN-VRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSSPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSRLM----YYILEI--RKGISNDSQNQSLRWKMVFNGSCNSLCTWKSKNL
RGTFQFRAVAANNIGFGEYSGISEDITLV--EDGFWITETSF--VLAVIV--GIFLVATV
SLTFVWYRSMKNRKISKEGLSVLNEDDKELAELRGLEAGVGLANACYAVHTLPTQEEIEN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTF-HGPLLTLVD
LVEVCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS--------DV--WSFGILVWEILTLGHQP
YPAHSNLDVLNYVQEGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFRNIQDKLQL-FRH
VSLNNVSQCGEEAYASGVINKGFEGEEDKT-VVLNSD-DVVPVALMETKNQEGLSYMVLA
TKCSQGEENPEGPLGPKESLSHGL-KKDEKQSHADKDFCQEPQVAFCS-PSRSEGLNYVC
LTHSGHGDVSD-

MKNVYWLNLKL-----VNFATLGC-LWISLGQCTVLNNCLKSCVTNLGRQLDIGTPYN--
-LSEPCIQGCHFWNSVDQENCALKCNDTYATVC--ERESCEIGCSSAEGAYEEEVLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWKSTNISGVKYIIQWKYTQLLGSWTYTETVSKPSYVAEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLQLHSPPSPSYRTH-P------YGVPEA

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESNITT-PSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----SDAIHHN
I---TGISVDVHQQAV-----YFSAGTLIWVKEAADMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDQLVYVCDLENCLNIEEITPLSL
IAPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---GGEAQAMRIVESCTLKDFTV----K
PQS----KRIIYFNDTTQVFMSTFLDGSASHFVLPHVPFA-NVKSFACENNDFLVTDGKA
VFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGLSTQLHPLPGRPQELSVL
FGSHQALVQWKRPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DLHEITRVFSNISGTMLNVPQLQSATKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMK
GDVYVWLLNGT-DISENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHADIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAILRGQS-VGNTIIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIAQRTSVSVLEAAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQVSSFRIEGNASSFQVLWDAPPAVDWGAVFYSVEFSAPSK
FLASE--------RQPLPAFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFALLSGKYH

PF00041 // ENSGT00760000118818_6_Domain_4 (1517, 1614)

NRNE-VVVEFRWDKPKHANGVLTRFEIFYQISNQS---------
---DTNRTFDDWIAVNV---TPSMMSLQLEGMSPRCLVAFQVRVFTSKGPGPFSDIIKST
ISEINPFPYLITLLGNKIVFLDMDQNQVVWTFSGERDISAVGYT----ADNEMGYY----
AEGNSLFLLDLHNHSS---SELLRDALVFDIT-VITIDWISRHLYFALKEPQNGMQIFDV
DLEHKVKYPRELK--ICNRNSTIISFSVYPLLS--RLYWTEVSDLGYQMSYYSIINHTLH
HILQPTATNHQNGRNQCSCNVTEFELSGAMTIDTSDLEKPLIYFVKA-QEIWAMDLEGCQ
CWRVIMVPAMI--GKTLVSLTVDGEFIYWIITAKTSTQIYQAKKRNGAILSQVKTLRSKH
ILAYSSVMQPFPDKALLSLASDIEEPTILNATNISLTIKLPLAKTNLTG-YGITSPTPTY
LVYYTEVNGKRNSSN---LKYRM-----LEFQDSIALIEELQPFSTYMIQIAVKNYYSDS
LEHLPLGKEIWGKTKSGVPEAVWLINTTVRSDTSLIISWRESPKPNGPKESVRYQLAILH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNLYML--KVLACHSEEMWCAESHPVTVETFG
TPEKPYAL

PF00041 // ENSGT00760000118818_6_Domain_7 (2169, 2246)

VPENTSLQLHWKAPSNVNLIRFWFELQKWKY--NEFYHIKASCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YVTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSFPESFKT----KAGVPSKPGIPKLLEGSKNS
VQWEKAEDNGNRLM----YYILEI--RKFTSNDSQDPNLSWKMTFNGSCSGICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG--DGFGIPETSF--ILTVIV--GILLIVTI
PLTFVWHGRLKNQKAPKEGLAVLVNEDKELAELQGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFSHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTPF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMIHCWAQEPDQRPTFHKIQDQLQL-FRN
FSLNSVSQCRDEANTRGVINEGFEGEGGN-MICVNSG-DAMSIALMETKNQEGLNYMVLA
TDCSRGEENSEGLPGSQESESCGL-REEEKEPHADKDFCQEKQVAYCP-PGKPGGLNYAC
LTHSGCGDGSD-

MKNIYCLIPKL-----VNFAALGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLENAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYGQLLGSWTYTKTVSRLSCVVKPLH
PFTEYIFRVVWIFTTQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPEAESIITT-SSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---GRCAEAVHIVESCTLKDFAI----K
PQA----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQALVQWKPPAFAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQKTSVSVLEPARFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYNISNQS---------
---ITNKTCEDWIAVNV---TPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAFCYT----ADNEMGYY----
AEGDSLFLLHLHNRSS---SELFQDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSNFGYQMFYYSIINHTLH
RILQLTTTNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCR
CWRVITVPAMLAG-KTLVSLTVDGDFIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVYYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPLNVNLIRFWVELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGIPNKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-D-DFWIPETRF--ILTIIV--GIFLVVTI
PLTFVWHRRLKNQKSAEEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANNSGVINESFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-SGKTEGLNYAC
LTHSGYGDGSD-

MKNIYWLILKL-----VNFTTLRC-IWISMVQCTVLNSCLKLCVTNLGRQFDIGIPYN--
-LSEPCIQGCHFWNTVNQENCALKCNDTYGTVC--ERESCEIGCSSAEGAYEEEVLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PYVSSIGSHSVALRWKPVNISGVKYIVQWKYAQLLGSWTYTKTVSKLSYVVKPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIFTAQLQLYSPPSPSYRTH-P------YGAPETAPVIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQGTSFQFYCTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-SSPAVQEAEQWLFLSRKSSLRKRSLKHLVDEAHCLQ----SDTIHHN
I---TGISADVHQQVV-----YFSEGTLIWVKEAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RLYFIMDELVCVCDLENCSNIEEITPSSI
SAPKKIVADAYNGYVFYLLCDGIYRTDLPVPS---SRDTHTMHIVESYTLKDFAV----K
PQA----KRIIYFNDTTKVFMSTFLDGSASHLILPHALFA-DMKSFAWENNDFLVTDGKA
VFQQ-----DTLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSTQLHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

PPLELSVL
FGSHQALVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DLPEIAHVFSNIHGTTLNIPELESATKYKVSVRASSPKGPGPWSEPMVG--TTLVP----
--------AMEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIRNVSDMDWYNNSLYYSNMK
GDVYVWLLNGK-DISENYHIPRIAGAGTLAFEWLGHFLYWAGKTYVIQRLSVLTGHTDIV
THVKLLVNDMVVDSIGGYLYWTTLYSVESTRLNGESSLILQALPLLSGKK----------
------------------VVALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-FGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPTVIPNSVQESSFRIKGNASSFQILWNAPPAVDWGVVFYSVEFSAHSK
FLTSE--------QQSLPIFTVEGLEAYTLFNFSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRTFILPSGKYYNK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1614)

NE-VVVEFRWNKPKHENGVLTRFEILYQMSNQS---------
---DTNKTFKDWIAVNV---TPSVMSFQLEGMSPGCFIAFQIRAFTFKGPGPFSDIVKST
TSEINPFPYLMILLGNKIVFLDMDQNEVVWTFSAEGDISAMGYT----ADNEMGYY----
SEGGSLFLLNLHNRSS---SELFRDAKFSEIT-VITIDWIARHLYFALRVSQNGMQIFDV
DLEHKATYPRKLK--ICNRNSTIISFSVYPLLS--RLYWTEVSDFGYQMFYYSITNHTLH
RILQPTATNQQNGRNQCSCNVTESELSGVMAIDTSDLKKPLIYFAKA-QEIWAVDLEGCQ
CWRVIMVPAMF--GKTLISLTVDGEFIYWIITAEDNTQIYQAKKRNGDVFSQLKARRSKH
ILAYSSVMQPFPDKAFLSLASDIAEPTILNATNTSLTIKLPPAKTNLTW-YGITRPTPTY
LVYFTEVNDRKNS--------RM-----LEFQDTIVLIEDLQPFSTYMIQIAVKNYYSDP
LEHLPLGKEIWGKTRSG-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------

MKDIYWLILKR-----VNFVTVGC-IWISVVQCTVLNSCLKSCIINLDKQSDIGTPYN--
-LSEVCIQGCHFWNSVDQENCTLKCR-----------ESCEVGCSSAEGAYEEEVLENAD
LPTP-PFASSIGNHSVTLGWKAANISGVKYVIQWKYTQHPGSWTYTEXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X------XXX

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPFIKNMESSSPDTVE
VSWSPPQFPGGPILGYNLRLTCKNQNLAAGTQRTSFQFYSTLPSTTYR---FSIAAVNEV
GEGPEAESNITT-TSPEVQEEEQWLFLSRKTSVRKRSLKYLVDEAHCLQ----SDVILHN
I---TGISVNIHQQVV-----YFSEGNLIWVKETANMSDVSNLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YNGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RLYFIMDKLVFVCDLENCSTAEEITPPSI
DAPQKIVADSYNGYVFYLLRDGIYRVQLPLSS---AQDSKAVQVVESGTLKDFVV----K
PQS----KRIIYFNDTAHAFVSTFLDGSASHLVQPHVSLT-DVKSFACENSDFLVTDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLLIFGSSAQLHPLPGRPQQVSVL
FGSHQALVQWRPPALAIGANII----------LVSNII---IKYGPSAQNWTYEVEVSTE
DFXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXX--XXXXXX---
------XXXTEPPFIMAVKEDGLWSKPLNSFGPGQFLSSDIRNVSXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIQRQSLLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTPYSVESTRLNGQSSITLQAQTWLSGKK----------
------------------VIALTLDLSDRLLYWLVQDSECIHLYTAVLRGQS-VGDTIIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSRTPKVIPDSVQESSFRIQGNASSFQILWDAPPLVDWGMVFYSVELSAHSK
FLASE--------QWSLPVFTVEGLDPCTSFNLSVTPYTFWGKGPKTSLSLRAPET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRIFVLPSGKYSKKNE-VVVEFRWNKPKHANGVLTSFEILYQISNQS---------
---DTNKILKNWIAVSG---IPSVMSFQLEGVKPESIVCFQVRAFTSKGPGPFSDIAKSN
TSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXX----
XXXXXXXXXXXXXXXX---XXIFRDALVCDIA-VITVDWISRHLYFVLKESQNGTQIFDV
DLEHKVKYPRVLE--TCNRNSTIISFSVYPLLS--RLYWTEISSLGCQILYCSIANRTLH
HILQSTTTDYQNGRSQCSCNVTESELSGAMTIDSSDLKQPCIYFVKG-QEIWAMDLEGCQ
CWRVIMVSAML-AGSALVSLTVDGEFIYWIVMAKDNTQIYQAKKRNGTVPFQVKAPRSKH
ILAYSPVMQPFPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXXX---XXXXX-----XEFQGSI-VLEQLQPFSTYVIQIAVKNYYSDS
LKQLPLGKEIWGKTKSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX-XXX-XXX
XXXXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX-XXESTPNDLQNSNLKWKVAFNGSCDSICTWKSKNL
IGTFQFRVVAASNLGFGQYSGISENVVLI---RDFWLPETSF--ILAITV--GILI-LTM
SLSFVWHTRLKNQKSSKEGLAVLIDEDKDLPEPRGTATGVGLANACYAIHTLPTQDEIES
LPAFPREK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2756)

LTLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTKI-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLVDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFRKIQNQLQL-FRN
FSLNNISHCHDEANTSGVVNKGFEDEDNS-KICLNSK-DITPIALIETKNQEGLNYMVLA
TECSRGGQHSEGPLGSKESESCGL-RKEEKEPHADKDNCQEKQVAYCP-PGKPEGLNYAC
LTHSGYGDGSD-

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---------GFS-VPVIAPGLRSQLISLSPVH--SW----VTGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSGLI----YYILET--RKITSGDSQNQNLRWKMAFNGSCSSICMWKSKNL
KGTFQFRVVAVNHLGFGDYSGVSENIILAG--DDLRIPETSF--ILTIIV--GVFLVITI
PLAFVWHKGLKNQKTSEEGLTVLIGEDKELAELRGPVAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRVLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFDHPNILKQLGVCLLNEPQYLILELMEGGDLLTYLRKARMTTF-HGPLLTLAD
LVDLCVDVSKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMAQCWAQEPIQRPTFHEIQDQLQL-FRK
FPLNTISQCRGEVNTTEVINKGFEDDDDS-TIRLNSD-DATPVAFMVTRNQEGLNYMVLA
TELSPSRDNSEGPLCFKDPKSCAL-RKGEKELQADQDFCQEEQVAGCL-PGASPGLNYAC
LTHGGSGERSDP

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCNFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTMYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAETVRIVDSCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTRIFSNISGTRLNVPELQSAMKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWQLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPVVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVDV---TPSVMSFQLEDMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIVLLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINCTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCH
CWRVITVPAVL-G-KTLASLTVDGDFIYWIITAKDSTRIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-HGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
APEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPGKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFMVITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATTYYGYLFDFWN
FIVV--------VIIIKYNFCHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEILENAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSRLSYVVKPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 304)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPGAESSITT-SSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAEAVRIVESCTLKDFAI----K
PQA----KRIIYFNDTAQVFTSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYIYWTTLYSVESTRLNGESSLVLQTQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQKTSVSVLEPARFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFILPSGKCCN

PF00041 // ENSGT00760000118818_6_Domain_4 (1518, 1613)

KNE-VVVEFRWNKPKHENGVLTKFEIFYNISNQS---------
---TTNKTCEDWIAVNV---TPSVMSFQVEGMSPRCFIAFQVRAFTSKGPGPFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYT----ADNEMGYY----
AEGDSLFLLHLHNRSS---SELFQDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSNFGYQMFYYSIINHTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCQ
CWRVITVPAMLAG-KTLVSLTVDEDFIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSPASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVYYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKKIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPLNVNLIRFWVELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPNKPGIPKLLEGSKNS
IQWEKAEDNGCRIT----YYILEI--RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-D-DFWIPETSF--ILTIIV--GIFLVVTI
PLTFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLERMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANNSGVINESFEGEDGD-VICLNSD-DLMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-SGKTEGLNYAC
LTHSGYGDGSD-

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCQ-----------ESCEVGCSSAEGAYEEEVLENAD
LPAA-PFASSIS--PMTLRWKSANFSGV-YIIQW-YAQLLGSWTYTKTVSRLSYVVELLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPEAESSITT-SSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----LGAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAEAEHIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNISGTMLNVPELQSATKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYCSDMK
GDVFVWLLNGT-DISENYHLSSIAGAGALAFEWLGRFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRMITTQEIGQKTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAYSK
FT-SE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGK-PKTSLSLRAPET-VPS
APENPRIFILPSGKCCNK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1612)

NE-VVVEFRWNKPKHENGVLTKFEIFYNISNQS---------
---ITNKTCEDWIAVNV---TPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVAWTFSAERVISAICYT----ADNEMGYY----
AEGDSLFLLNLHNRSS---SELFQDSLIFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSNFGYQMFYYSIINHTLH
RILQPIATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCQ
CWRVITVPAMLAG-KTLVSLTVDGDFIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNAANTSLTIRLPLAKTNLTW-YGITSPTPTY
LVYYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCKESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPLNVNLIRFWVELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPETFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNL
KGIFQFRVVAANNLGSGEYSGISEKIILVG-D-DFWIPETSF--ILTIIV--GIFLVVTV
PLTFVWHRRLKNQKSAKEGVTVLINEDKQLAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNRIYQCRDEANTSGVINEGFKGEDGD-VICLNSD-DIMPVALRETKNQEGLNYMVLA
TECGQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-SGKPEGLNYAC
LTHSGYGDGSD-

MKNTHLWVFPL-----KRLLAFCC-LWISAAHCAFSRNCYNLCTSNLEGELGITNLCNVS
DITGACIQGCQFWNATAQTDCPLKCNETYTRAC--ETVSCKFGCSCAEDAYGAEALNYLN

PF00041 // ENSGT00760000118818_6_Domain_0 (121, 190)

KPSA-PFASLIGNHSITLGWKAANISGVKYVIQWKFNKLPGDWKYTEVVSETSYTVKDLQ
AFTEYVFQVVWIVTSQLQLHSPPSPSYRTQA-------FGAPATAPVIKDIQSSSPNTVE
VSWSPPVFPNGLIIGYNLLLTSENHELLRASRGHSFQFYSTFPNTTYRCTRFSIVAVNEV
GAGPRAEANITTPPSKV-KEKAAWLFLSRKESLRKRYTGHFLEAAQCLP----DGNIHHN
I---TGISVNIYQQVI-----YFSEGNSIWVKGVANMSDVSDLLLF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YAGWGNIVSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RIYFVMDGKIHVCHLENCTVAEDITPLYV
MSPRKVIADPYNGYIFCLLEDGIYRASLPLFP---GTASAASPVVRSSALRTFTI----N
FQS----KRLIFFNKTEQAFVSGFLDGSEFHTLRSRVPLD-DTESFVYEDNTFTVTDGSA
VFHEEVSPEGSSSFNEYIVDCNLDY----PEYFGIGNLVFYRPSTQPFPLPTA

PF00041 // ENSGT00760000118818_6_Domain_2 (954, 1064)

PHLVTAL
FGVDRAVISWRPPEHTIGTS------------------------LSAWQNWTYDVKVSPQ
LPSEEEWVVSNISNTRLTVKGLASFTAYEVSVRAVSPAGAGPWSEPFRG--TTLEE----
--------AEEEPYMLAVGPEGLWKQRLDSYRPGELLYPHIRNVSDLDWYNNSLYWINSM
GEVQTWPLNKRKGTTESTYVSDVRNARMLAFDWLGQCLYWAGKANTIYRKSLWGGHIDVV
AHVVFPVKDLVVDSVNGYLYWATMYSVESTRLNGEEYLVLQEQLQFSGKQ----------
------------------VVGVTLDLIHGFLYWLVQDNLCLNLYRASLCKEG-CGNAIIT
EFAAWSTSEISQGALEYYSGRLFWINRLQILTVQEVNQSISIPFSQPAQFTAFTLVQASL
KPLP--GNFSSTPKVIPDSVPESSFRIKGNSSSFHITWSPSTKVEWGTVFYCVGSKALQ-
LQSLESEGCLHPHNLTVPSYRVDWLEPFALFDFTVTPYTYWGKAPMTSVSLRAPEG-VPS
APRNPRIYVLQNNLHGSDGR-IL

PF00041 // ENSGT00760000118818_6_Domain_4 (1524, 1614)

VEFRWDRPERDNGILTQFKVYYQLLNQS---------
---STAGSSMEWTESNV---KPTQTQFSLKDVLPSLTVRFQVQAFTSVGPGPLSDMAERN
SSDLFPIPTLITISASKLFLTNIDSGQTIWELSAKTNVKDICYT----ADDDKAYH----
ITGDSLFVLNVQNASM---FQFFKDAYLHNVT-AITVDWIARHLFVALKTPQDETQIFVI
DLELKKKSLKALNIQLGKSNSTVSSLLSYPFLS--RLYWMEELDNGSHMFYYDILNSTLH
HVLGQGLVE-KQMRN-CTCNVTEAELGRPMSIDLSDSKNPQLLFIRGREEIWASDVDGCH
CWKIIKIPNIQ--GNKIGSLTADKKFIYWTAETKEYTEIWLANKESRRHFLHKRANHTLK
ILAYSSAAQSYPDKRCLTLLPDAEKPTILAKTNTSFTLSLPSVTPQQPC-PGISQPTPTY
LVFSRQMTNICKSSR---QCLSAPQQTTLEYQGPIAVLENLQPFSSYVIQVAVKNYYSDE
G-VLPVGEGTVGTTLYGVPEAVDTIKALVLSDTTINISWSEPLKPNGPLESIRYQISVNL
LPPVPATPLRKSEFSNGMLAWSVSGLQPGTNNSFK--VLAFHPDENWFSESVPVIAKTFE
SPAAPINIVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2248)

RNTSFQLEWRAPLDINGTSFWFELRKWPTKSDWFSPANTTCT-GNLVYTC
NLTGTLPWTNYF-VRVSVV-YVTGVKS

ENSGT00760000118818_6_Linker_7_9 (2248, 2469)

TSSSTSFKTS----AGVPGKPGVPKRAEDSKTS
LQWEKADDNGSKLT----YYILESRKQS---GNSSDVKSMWEVVYNGSCGSICTWKAKNS
EGTFQFRAAAANMLGLGEYSDISMDIILSE--DKMTSIGT--IIAISSVIGVVLCLALFM
LLGFVWKQRLKPRKPALPGQIVFIKEDKELAQLRGMAEVVGLANACYAVRTLPSQAEIES
LPAFPRDK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LNLHKLLGSGAFGEVYEGTAVDILADGSGESKVAVKTLKKGATDQEKSEFLK
EAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKKKL-QSPLLRITD
LLDICLDVCKGCVYLEKMHFIHR-DLAARNCLVSEKEYGRSSRIVKIGDFG--LARDVYK
NDYYRKRGEGLLPVRWMAPESLIDGVFTSRS----------DVWAFGVLVWETLTLGQQP
YPGFSNTEVLHHVRSGGRLESPNNCPDDLCDLMTRCWSQEPHNRPTFSNIHDKLQE-IRH
SPLSFIHCLEGKEGSTGVINEAFE--DNE-IPCADSD-SILSATLMETRNQEGLNYLVLV
KEGNPDEESIN-------SAEIRC-V----------------------------------
------------

MKNVYCLIPKL-----VHFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCYFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLENAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSRLSYVVEPLH
PFTEYMFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPEAESSITT-SSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAVYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNVEEISPPSI
SAPQKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAEAVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKI
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNVSGTVLNVPELQSATKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGELLSSDIGNVSDMDWYNNSLYYSDMK
GDIFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDMV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGKS-TGDTTIT
EFAAWSTSEISQNALVYYSGRLFWINGFRIITTQEIGQKTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYTLFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFILPSGKCCN

PF00041 // ENSGT00760000118818_6_Domain_4 (1518, 1613)

KNE-VVVEFRWNKPKHENGVLTKFEIFYNISNQS---------
---ITNKTCEDWIAVNV---TPSVMSFQLEGMSPGCFVAFQVRAFTSKGPGPFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWAFSAARIISAICYT----ADNEMGYY----
AEGNSLFLLNLHNRSS---SKLFQDSLVFDIT-VITIDWISRHLYFALKESQHGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINHTLH
QIVQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCQ
CWRVITVPAMLAG-KTLVSLTVDGDFIYWIITANDSTQIYQAKKGNGAIISQVKALRSRH
IVAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LIYYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMVQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPRESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPLNVNLIRFWVELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-D-DFWIPETSF--ILTIIV--GIFLVVTI
PLTFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATY-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDHRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINEGFEGEDGD-VICLNSD-DIMPVALMETKNPEGLNYMVLA
TQCGQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-SGKPEGLNYAC
LTHSGYGDGSD-

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLSSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAERAYEEEVLGNAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTETVSKLSYVVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTMYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIVDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAETVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTRIFSNISGTRLNVPELQSATKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------RHSLPVFTVEGLEPYALFNLSVTPYTYWGKGSKTALSLRAPET-GTG
ESL--IILIMQERK--------------RKP---SG--CPNKIFNQISNQSLLQMLVNDR
NLCKANTGFGRWEELNK---YR----------YPFPIAFFTVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFGIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQIKKCKIFIL---
------------------------------------------F-----------------
----FIFLTFLTSGKTLASLTVDGDFIYWIITAKDSTRIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-YGITSPTPTY
LVCYAEVNDRKNNSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLKV-HSY--------------------
------------------------------SLIEKNWKY--NEFYRVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGENSTSLPESFKT----KAGVPGKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

MKNVYRLILKL-----FNFVTLSC-LWISLGQCTVLNSCLKLCVTNLGRQLDIGTPHN--
-MSEPCIQGCHFWNSVDQENCALKCNDTYATVC--ERESCEVGCSSAEGAYEEVVLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHNVTLRWKSANISGVKYIIQWKYAQLPGSWTYTKTVSKPSYVAEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLQLYSPPSSSYRTH-P------YGVPEAA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNVESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-SSLAVQEEEQWLFLSRKTSLRKRSLKHLVDEAQCLQ----SDDIHHN
I---TGISVDVHLQVV-----YFSEGTLIWMKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMNELVCVCDLENCLNLEEITPPSI
VAPQKIVVDSYNGYVFYLLRDGIYRVDLPVPS---GWDAQAMRIVDSHTLKDFAV----K
PQS----KRVIYFNHTTQVFMSTFLDGSAFHLVQPHVPFA-SVKSFACENNDFLVTDGKA
VFQQ-----DALSFNEFIVGCELSH----IEEFGFGNLVIFGLSTQLHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQALSVL
FGSHRALVQWKPPALAIGA------------------------SPSAWQNWTYEVELSTQ
DLPEITHVFSNISGTMLNVPELQSATKYKVSVRASSPKGPGPWSEPLVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNRLYYSDVK
GDVYVWLLNGT-DISENYHIPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHADIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESALILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-AGDPVIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEAAKFSQFTIIQTSL
KPLP--GNFSFTPKVIPDSVPVSSFRIEGNASSFQILWDAPPAVDWGAVFYSVEFSAHSK
FLASE--------QQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPQTSLSLRAPET-VPS
VPENPRMFTLPSGKHHN-DE-VV

PF00041 // ENSGT00760000118818_6_Domain_4 (1524, 1614)

VEFRWNKPKQENGVLIRFEIFYQVSNQS---------
---DASETFENWIAVMV---SPSVMSFQLEGLSPRCSVAFQVQAFTSKGPGPFSDIVKST
VSEINPFPYLITLGDSKIQFLDMDQNQAVWTFSGERGISAVGYT----ADNEMGYY----
TEGNSIFLLDLHNHSS---SEVLRDALVFDIT-VIAIDWISRHLYFALKEAQNGIQIFDV
DLERKMKYPKELK--ICGRNSTIISFSVYPLLS--RLYWTEVSNLGYQMFYYSIINRTEH
RLLQPTAKNQQNGRNQCSCNVPEFELSGAMTIDTSDLEKPLIYFAKT-QEIWAMDLEGCQ
CWSIVMVPTVL--GKKLLSLTVDGEFIYWIFTAKASTQIYQAKKRNGTILSHVKTIRTKC
ILAYSSVMQPFPGKSYLSLASEIAEPTILNATNTSLTIKLPPAKTNLTG-YGITSPTATY
LVYYTEVNGGKNSSG---SKDRM-----LELQDSIALIEDLQPFSTYMIQIAVKNYYSAS
LEHLPLGKEIWGKTKSGVPEAVRLINTTVRSDTSLLISWRESYKPNGPKESVRYQLAISH
LALIPETPQRQSEFPNGRLTLLVTRLSGGNLYLLKKKVLACHSEERWCSESHPVPVEMFD
TPEKPYALVPENTSLELHWKAPSNVNLIRFWFELQKWRY--NEFYHIKASCS-QGPAYVC
NITDLQPHTSYN-IRAVVV-YMTGENSTSLPESFKT----KAGVPSKPGIPKLLEGTKNS
IQWEKAEDNGNRLI----YHILEI--RKGTSYDSQDPNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENITLVG-VDGFGIPETSF--ILTIIV--GIFLTVTI
PSAFVWH-RLKNQKTPKEGLAVLVNEDKELAELRGPAAGVGLANACYAIHTRPTQEEIEN
LPTFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLNYLRKARMTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGVLIWEILTLGHQP
YPAHSNLDVLNFVQTGGRLEPPRNCPDDLWNLMIHCWAQDPDRRPTFHRIQEQLQL-FRN
FSLNSISQCKDEANTSGVINEGFEGEVGN-MICLNSG-DIMSIALMETKNQEGLNYMVLA
TECSQHEENSEGLLGSQESEPYGP-KKEEKEPHADKDFCQEKQVAYYP-PGMPEGLNYAC
LTHSGCGDGSD-

MKSKGWLALKP-----LNTVILGC-VWVSAVQCTVLSSCLASCVTNLGRPLDIGTPYN--
-LSEACIQGCQFWNSQDQEKCALKCNDTYATIC--ERESCEIGCSTAEGTYEEEVLESTE
F

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWNPANISGVKYIIQWKYDQLPGSWTYTETVPKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRT-HP------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIMKIESSSPDTVE
VSWAPPHFPGGPVLGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 954)

EAESIITT-PSPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDTIHHN
I---TGIAVDVQQQVV-----YFSEGTVIWMKKAANMSDMSDLRAF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YGGSGVISSISIDWLYR----------------
------------------------------------------------------------
-------------------------------RMYFIIDKLVYVCDLENCSNFEEITPLSI
VAPQKVVVDSYNGYVFYLLRDGIYRVSLPLPS---GRHTEAVHIVESSTLKDFAV----K
PQS----KRIIYFNDTVQVFMSTFLDGSAFHQVLPWVPLK-DVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSIQSYPLPGH

PF00041 // ENSGT00760000118818_6_Domain_2 (954, 1064)

PQELSVL
FGSQEALVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DLPQVTQVFSNLSGTMLNVPELQSATKYMVSVRASSPKGPGPWSDPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DASENYHIPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
AHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGRG-AGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSESAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSVQESSFRIEGDTSNFQILWTEPPAVDWGIVFYSVEFSAQSK
FLAIE--------QQSLPMFTVEGLEPYALFNLSVTPYTYWGKGQKTSLSLRTPES-VPS
APENPRIFILSCGRYVNKNE-VVVEFRWSKPKHANGVLTKFEIIYRISEQS---------
---GTNKTTEDWISVNV---IPPVMSFQLEAMSPGYIVAFQVRVFTSKGPGPFSDMVVSK
TSEIKPFPYLISLLGNKIVFLDMDQKKVLWTFSTEGDISTVGYT----ADDEMGYF----
VQGDSLFLLNLHNRSS---SKLLQGALVSDVA-VTAVDWIARRLYFALKTSQDGTQMFDV
DLEHKVKSPRELK--ICKRHSAIISFSVYPLLS--RLYWTEVSDLGHQMFYCSISNHTLH
HIVQPKASS-PHGRRQCFCNVTESELGGAMTADTSEPKRPRIYFTKG-QEIWAMDLEGCQ
CWKVTMAPAI-L-GKRIASLTVDREFVYWIITTKDNTQIYQAEKGSGAVVSQVKAPGSKH
ILAYSSALQPLPDKAYLSLASDMVEATILNATNTSLTLKLPPAKTNLTW-HGITSPTPTY
LVYYTEANNT-NSHN---RKHRI-----LESQETVAHIEDLRPFSAYVIQVAVKNYYSDP
LGHLPLGKEIQGKTTSGVPGAVCHINATVLSDTSLHVIWTESDRPNGPQESVRYQLVMSH
LAPIPETPLRQGEFPSARLALLVTKLSGGQLYVLK--VLACHSEEMWCTESHPVTVNMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2247)

TPEKPSALVPDNSSLRLNWKAPSNVNLTRFWFELQKWKY--NEFYHVEASCS-QGPVYVC
NIADLQPYTPYN-VRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSSPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSRLM----YYILEI--RKGISNDSQNQSLRWKMVFNGSCNSLCTWKSKNL
RGTFQFRAVAANNIGFGEYSGISEDITLV--EDGFWITETSF--VLAVIV--GIFLVATV
SLTFVWYRSMKNRKISKEGLSVLNEDDKELAELRGLEAGVGLANACYAVHTLPTQEEIEN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTF-HGPLLTLVD
LVEVCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS--------DV--WSFGILVWEILTLGHQP
YPAHSNLDVLNYVQEGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFRNIQDKLQL-FRH
VSLNNVSQCGEEAYASGVINKGFEGEEDKT-VVLNSD-DVVPVALMETKNQEGLSYMVLA
TKCSQGEENPEGPLGPKESLSHGL-KKDEKQSHADKDFCQEPQVAFCS-PSRSEGLNYVC
LTHSGHGDVSD-

MKNIYCLILKL-----VNFATLGC-LWIFVVQCTVLNSCLKSCVTNLGQQLDLDTPHN--
-LSETCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSTAAVNEV
GEGPEAQSSITT-SSSAGQEEEQWLFLSRKTSLRKRSLKHLVDEAYCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GQCAEAVRIVESCMLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASRLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGANV----------ILTGDIIEPFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFSNISGTMLNVPELQSATKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------RHSLPVFTVEGLEPHALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPEHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVNV---TPSVMSFQLEGMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINRTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCH
CWRVITVPAMLGKMKTLASLTVDRDFIYWIITAKDSTQIYQAKKGNGVIVSQVKALRSRH
ILAYSSVMQPFPDKVFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVLYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYRIQIAVKNYYSDP
LEHLPPGREIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPSKPGIPKLLEENKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSRNL
KGVFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINESFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECSQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LTHTGYGDGSD-

MKNLYWLSLKL-----VNFATLGC-VWISVGQCTVLNSCLKSCVTNLGRQLDVGTPHN--
-LSEPCIQGCHFWNSADQENCALKCV------------------------------KNAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGMTLRWKSANISGVKYIIQWKYTQLPGSWTYTEAVSKLSYVVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLHLYSLPSPSYRTH-P------YGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-PSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----SDATHHN
I---TGISVNVHQQVV-----YFSEGTLIW------------------------------
-------------------------------------V-----K------D-----A---
--A------N-----M-----S------D-----V-----S------G-----L-----R
-----I------F-----Y-----R------G-----S-----G-----L------I---
--S-----S------I-----S-----I-----D------W-----L-----Y------Q
-----K-----M------Y-----F-----------------------------------
-----------------------------------IMDELVCVCDLENCSNIETITPPSI
IAPQKIVADSYNGYVFYLLRDGIYRVNLPVPS---GGGSEAMRIVQSGTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHIILPHVPFT-NVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSYTQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQQLSVL
FGSHQALVQWKPPTLAIGASE----------F--------PVPRPSAWQDWTYEVKVSTQ
DLPETTHVFSNISGTILNVHDLQSATKYEVSVRASSPKGPGPWSEPSVG--TTLVP----
--------AAEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMK
GDVYVWLLNGT-DISENYQIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGRTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESPLVLQAQPWFSGKK----------
------------------VIALTLDLSDGFLYWLVQDSQCIHLYTAVLRGQS-AGDTTIT
EFAAWSTSDISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIVQTSL
KPLP--GNFSFTPKVIPDAIPESSFMIEGNASGFHILWNAPAAVDWGVIFYSVEFSAHSK
FLASE--------QQSKPVFTVEGLEPYALFNLSVIPYTYWGKGPKTSLSLRTPET-VPS
APENPRIFILPGEKHCNK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1614)

NE-VVVEFRWNKPQHENGVLTRFEIFYQIANQN---------
---DTNRTVEDWLAVNV---TPSVMSFQLEGVSPGYSVAFQVRVFTSKGPGPFSDIVKSK
TSEINPFPYLITLADNKITLLDMDRNQVTWTFSAEGDVAAMGYT----ADDAVGYC----
AQGDSLFLLRMDNRSS---TKIFRDPLVFDIT-FITIDWISRHLYFVLKESQSGMQIFDM
DLENKVKYPRKLK--VCNRNSTITSFSVYPFLS--RLYWTEVFDSGSQMFYYSIMNQTVH
RILQPPVINHPN-GSQCSCNVTESELSGAMTIDTSDLKKPQIYFVKG-QEIWATDLEACQ
CWQVIILPAPL-AGKMLVSLTVDGEFLYWISKAEDSTQIYQAKKSNGAILSQVEAPRSKH
ILVYSSVLQPFPDRAFLSLASDIAEPTILNTTNTSLTIRLPPARTKLTW-DGITCPTPTY
LVYYKEVIDMKNSSE---LRDKM-----LEFQESIAFIEGLQPFSTYMIQIAVKNYYSDP
LEQIPLGKEIWGKTKSGVPEAVWLINTTAQSDTSLVISWRESHKPNGPRESVRYQVAISH
LAPIPEIPLRQSEYPDGSLSLLVTRLSGGKLYVLK--VLACHAEEMWCAESHPVTVETFD
SPEKPYAFLPENTSLQLHWNAPSNVHLIRFWFELQKWKH--NEFYHVKASCS-QGPDYAC
NITDLQPYTSYN-VRAVVV-YRTGANSTSLPGSFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKADDNGSRLM----YYILEI--RKSTSNDSRNQNLTWKMAFNGSCNSICTWKSKNL
KGTFQFRVVAVNNLGFGEYSGISEDIILVG--DGFWIPETSF--ILTSII--GIFLVISI
PLIFVWH-RLKNQSTPKEGLTVLINEDKELAELRSLATGVGLANACYAIHTLPTQEEIES
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAIDILGAGSGETEVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTPF-HGPLLTLVD
LVDLCVEISKGCVYLEQMHFIHR-DLAARNCLVSMKDYTSPSRTVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEADQRPTFHKVQEQLQL-FRN
FSLNSISQCRGEANPSGVINEGFEDEDGH-PICLNSD-DVTSVALMETKNQEGLNYMVLA
TEYRQGETNSEGPLGSKESESCGL-RKEEKEPHADIAICQEKQVAYCP-PGKPGGLNYAC
LTHSGYGDGFE-

MKNVYWLILKL-----VNFVTLVC-VWISVVQCTVLNSCLKSCVTNLGRQLDVGTPYN--
-LSEPCIQGCHFWNSANQENCALKCNDTYTAVC--ERESCEVGCSSGEGAYEEEVLENAD

PF00041 // ENSGT00760000118818_6_Domain_0 (121, 190)

VPTA-PFASSIGSHSVTLRWKSANISGVKYIVQWKYAQLPGSWTYTEAVSKLSYVVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLQLYSPPSSSYRTH-P------YGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNIESASPDTVE
VSWAPPQFPGGPILGYNLRLISKNQQLDSGTQRTSFQFYSTLANTTYR---FSVAAVNEV
GEGPEAESSITT-SSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----ADAVRHN
I---TGISVNVHQQVV-----YFSEGAVIW------------------------------
-------------------------------------M-----K------E-----A---
--A------D-----M-----S------D-----V-----S------D-----L-----K
-----I------F-----Y-----R------G-----S-----G-----L------I---
--S-----S------I-----S-----V-----D------W-----L-----Y------Q
-----R-----M------Y-----F-----------------------------------
-----------------------------------IMDELVCVCDLDNCSNTEEITPPSI
IAPQKIVADSYNGYIFYLLRDGIYRVDLPGPS---GWDLEAVRVVQSSMLKDFAV----K
PQS----KRIIYFNDTLQVFMSTFLDGSASHLVLPQVPFM-DVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFDNLVIFGSYTQPHPLPSRPQQLSVL
FGSHQALVQWKAPALAIGAS------------------------PSAWQNWTYEVKVSTQ
DFPETTYVFCNISGTILNVHDLQSATKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVYMWLLNGM-DISENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VTALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-AGDTTIT
EFAAWSTSDISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPARFNQFTIIQTSL
KPLP--GNFSFTPKVIPDAIPESSFMIEGNASSFQILWSAPPAVDWGVIFYSVEFSAHSK
FLTSE--------QQPFPVFTVEGLEPYVLFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APEDPRIFVLPSEKYHNKNE-VVVEFRWSKPKHENGVLTRSEIFYQISNQS---------
---DTNSTLEDWIAVNV---TPSVMSFQLEGMSPGYIVAFQVRVFTSKGPGPLSDLVKSR
TSEINPFPFLITLFDNKIVLLDMDQNRVAWTFSAEGDFRAVGYT----ADDATGYC----
AQSDALLLLNMRNGSS---SEIFRDTLVFDIT-VITIDWISRHLYFVLKESQNRMQIFDI
DLENKVKYPRKLK--ICDRNSTIISFFVYPFLS--RLYWTEVSDFGSQMFYYSIINQTLH
RVLQPTAITRARGRSQCSCNVTEFELGGAMTIDTSDLKKPRIYFVKG-QEIWAMDLEGCQ
CWQVIIMPALL-AGQNLVSLAVDGAFLYWISTAKDSTQIYQAKKSNGAILSHVEALRSKH
ILVYSSVLQPFPDRAYLSLASDISEPTILNTTNTSLTIRLPPARTNLTW-DGITSPTPTY
LVYYKEVDGKKNSSR---LKDRM-----LEFQESIALIEGLQPFSTYMIQIAVKNYYSDP
LEQLPLGKEIWGKTKSGVPEAVELINTTVQSDTSLVISWRESHKPNGPKELVRYQVAISH
LASVPETPLRPSEYPNGRLSLLVTRLSGGKLYVLK--VLACHAEEMWCAESQPVTVETFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2246)

PEKPYALAPENTSLQLGWKAPSNVNLISFWFELQKWKH--NEFYHVKALCS-QGPAYIC
NITALQPYTSYN-VRVVVV-YSTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KPGVPSKPGIPKLLEGSKNS
IQWEKADDNGSRLM----YYVLDI--RKGTSNVSQNQNLMWRMAFNGSCSSLCIWKSKNL
KGTFQFRVVAVNNLGFGEYSGISDDIILVG--DDFWRPETSF--ILTIAI--GIFLVVTI
PLTFVWLRRLKNQKIPKEGLTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIES
LSAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARRTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHKIQDQLQL-FRN
FSLNSISQCREEASPSGVINEGFEAEDGH-MICLNSD-DVRSAALMETKNEEGLNYMMLA
TGCSQGEANSEGPLGFKESESCGL-RKEEKEPHADKDICQEKQVAYCP-PGKPQGLNYAC
LTHSGYGDGSD-

-------------MRRVGFTALGS-IWISAAQCAILNTCLKSCVTNLGEQPDLGTPHN--
-LSGPCIQGCHFWSSIHQENCAVKCNDTYAAVY--EREACEVGCSSAEGAYEEEVLENTN
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 191)

PTA-PFASSIGSHSVTLRWKSANISEVKYIIQWKYAQLPGSWTYTETVSELSYMTQALH
PFTEYVFRVV

ENSGT00760000118818_6_Linker_0_1 (191, 226)

WVFTAQLQLSSPPSPSYRTH-P------HGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIKNIESSGPDTVE
VSWTPPQFPGGPILGYNLRLISKNNKFDSGTQRTSFQFYSTLPNTTYR---FFVAAVNEV
GEGPEAESSITT-LSLAVQEEEQWLFLSRKTSLRKRSLKHLVEEAHCLW----SDGIQHN
I---TGISADVHRQVV-----YFSEGAVIWMKEVAHMSNVSDLRVF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISTDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMNELVYVCDLENCSNFEEITPPSI
IAPQKLVADAYNGYIFYLLRDGIYKVDLPRPS---GRDAKPVHIVESCTLKDFAI----K
PQS----KRIIYFNDTTQVFMSTFLDGSASRPVLPQFPFA-DVQSFACENNDFLVTDGKA
IFQQ-----DSMSFNEFIVGCDLSH----IEEFGFGNLVIFGSSTQPYPVPHRPKDISVL
FGSHQALVQWKPPALPIGAS------------------------PSAWQNWTYEVQVSTQ
DLPEFTQTFSNIHGVMLNIPGLQSAVKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTR
GEVHVRLLNGS-GVSESHRIPSIAGAGALTFEWLGRFLYWAGKTYVIQRQSVLTGHSDMV
THVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESALVLQAQPWFSGKKMYPSAMNYFH
SSDRRKHSQPFLIERHDYVIALTLDITDGLLYWLVQDSQCIHLYTAVLRGQS-TGDISIT
EFAAWSTSEISQNALMYYSGRLFWINGFRMITAQEIGQRTSVSVSEPAKFNQFTIIQMSL
KPLP--RNFSSTPKVIPDSVPESSFWIEGNASAFQVLWSSPPAVDWGVVFYSVEVSADSK
FLASE--------KQLLPVFTVEGLEPYALFNLSVTPYTYWGKGPRTSLSLRAPDT-VPS
TPENPRIFVLPSERSLNK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1614)

NE-VVVEFRWDTPRHENGMLIRFEIFYHISNQS---------
---DARRTSEGWTAVNV---TSSVTSFQLEGLRPGYTVAFQVRVYTSKGPGPFSDIVKSK
TSEISPCPYLMSFLGNEIVLLDVDQNQVVWTFLAQEDISALGYT----ADDDMGYF----
AQGDSLFLLNLHNRSG---SKLFQDARISGVT-LITVNWISRHLYFVLKESQNGTQIFDV
DLEHKMKRLRELK--ICNRNSTIVSFSVYPFLS--RLYWTEVSDLGCQMFYYSIINHTLH
HVLQPTATNQQNGRVQCSCNVTEFDLSGTMTIDTCDLEKPWIYFAKR-QEIWAMDLDGCQ
CWRVIVVPAVH-AGKALVSLTVDKEFIYWIITAKDSTQIYQAKKRDGAAVSQVKTLRSRC
ILAYSSAVQPFPDKAFLFLASDIAEPAILNATNTSLTIALPLARTNRTW-KGLASPTATY
LVYYAELHGRTNSSY---LKYKI-----LESQERIALIEGLHPFSTYIIKMAIKNYYSHS
REHLPLGQAILGKTKSGVPGAVGFINTTVLSDTSLLVSWRESHQPNGPGELVRYQLAISN
LPLIPKAPLRQSQFPNARLTLLLGTLSGGQLYVLK--VLACHSEEMWCAESHPVTVKMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2246)

PEKPYALAPDNTSLQLDWKAPSNGNLTRFWFELQKWKY--NEFFHVKASCS-QGPAYAC
SIADLQPYTFYR-VRVVVV-YVTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

RSLSPPESFQT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSGLM----YYILET--RKIISGGSQNQNLRWKMAFNGSCSSICMWKPKTL
KGTFQFRVVAVNRLGLGDYSGVSENIILTG--DDLWIPETSF--ILTSIV--GVFLVITI
PLAFVWHKGLKNQKNSKEGLAVLMREDKELAELRGPVAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRVLLGSGAFGEVYEGTAVDILGVGSGAVKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFDHPNILKQLGVCLLNEPQYLILELMEGGDLLTYLRKARMTMF-HGPLLTLAD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQAGGRLQPPTNCPDDLWNLMAQCWAQEPDQRPTFHKIQDQLQL-FRN
FPLNNISQCRGEANASEIVNEGFEDDNDN-RSSLNAD-GVTPIAFMVTRNQEGLNYMVLA
TEPSQSKDNSEGPPCSKESKSCSL-RKGEKELQGDQDFCQEKQVACCL-PGTAPGLNYAC
LTHGGSGDGSDS

------------RRRHVDFAALGS-IWISVAQCTILSTCLKSCVTNLGEQPDLGTPHN--
-LSGPCIQGCRFWRSTDQESCAVQCNDSYAAVC--EREACEVGCSSAEGAYEEEMLENTN
LPTA-PFAAAIASHSISLRWKSANISKVKYIVQWKYAQIPGSWTYTETVSRLSYVARALH
PFTEYIFRVVWVFTAQLQLFSPSSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISRSHKLDSGTQRTSFQFYSTLPNTTYR---FFIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESDIAT-PGLAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIRHN
I---TGISADVHRRVV-----YFSEGALIWMKEAAHMSNESDLRVF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISTDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMNELVYVCDLENCSHFEEVTPPSI
ISPQKLVADAYNGYIFYLLRDGIYRGDLPVPP---GRGTQPAHVVESRTLKDFAI----K
PQS----KRIIYFNETTRGFMSTFLDGSASHPVPPQFPFA-DVQSFACENSDFLVTDGKA
IFQQ-----DAMSFNEFIVGCDLRH----IEEFGFGNLVIFGSSTQPHPVPH

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

QPRDVSVL
FGSHQALVQWKPPALPIGAG------------------------PSAWQNWTYEVQVSTQ
DLPELTRTFSNIQGVMLDIPGLQSAMKYKVSVRAGSPQGQGPWSEPSVG--TTLVP----
--------AAEPPLIMAVKEDGLWSKPLHMFGPGVFLSSDIGNVSDMDWYNSSLYYSDTR
GDVHVRLLNGS-GVSEGRRIPSIAGAGALTFEWLGRSLYWAGKTYVIHRQSVLTGHADMV
TRVKLLVNDMAVDSLGGYLYWTSLYSVESARLNGESALVLQAQPWFSGRK----------
------------------VIALTLDLSDGLLYWLVQDSQCMHLYTALLRGQS-TGDISIM
EFAAWSTSEISQNALMYYSGRLFWINGLRMITAQEIGQRTSVSVSEPTKFDQFTIIQTSL
KPLP--GNFSSAPKVVPDPVPKSSFRVEGNASAFQVLWSSPPEVDWGEVFYSVELRAHSK
FLASE--------KQPLPVFTVEGLEPHAWFNLSVTPYTYWGKGSRTSLSLRAPTT-APS
TPENPRIFVLPSERPFSKNT-

PF00041 // ENSGT00760000118818_6_Domain_4 (1522, 1614)

AVVEFRWDKPKHENGTLARFEISYHTSNQS---------
---DANRTSEGWIAVNV---SGTVTSFQLKGMSPGYTVAFQVRVYTSKGPGPFSDIVKAN
TSEINPCPYLMSFLCNELVLFDVDQNQVVWTFLAEGDIGALGYT----ADDNIGYF----
SQGDSLFLLNLSNHSG---SKLLQDARISGIT-LLTVDWISRHLYFVLKESQNGTQIFDV
DLEHKVKHPSELK--ICNRNSTIVSFSVYPLLS--RLYWTEVSSLGCQMFYYSVAHRTLH
RILQPPATDRPNGRAQCFCSVTEFDLSGAMAIDTCELEKPWIYFSKR-GEIWATDLDGCQ
CWRVLRVPAVH--GKVLVSLTVDKEFIYWIITAKDNTEIYRAKKRDGASVSQVTTLRSQR
ILAYGSAVQPFPDKDFLLLASDTAEPAILGATNTSLAVALPPARTIRMW-KGLTGPTATY
LVYYAELDGRTNSSY---LKYKI-----LESQEKIALIEGLKPFSTYIIKMAIKNYYSDT
REHSPLGRAIWGKTTSGVPGAVGSINTTVLSDTRLLVSWRESHQPNGPGESVRYQLAISD
LPLIPEAPIRQSQFPNARLTVLLAALSGGQLYVLK--VLACHAVEMWCAESRPVAAKMF

PF00041 // ENSGT00760000118818_6_Domain_7 (2160, 2246)

D
PPEKPYALAPESTTVQLGWKAPANGNLTRFWFELQKWKY--SVFFHVKASCS-QGPAYAC
SISGLQPSTFYR-VRVVVV-YTTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

RSLSPPNGFQT----AAGVPSKPGTPKLLEGSRNS
VQWEKADDNGSGLM----YYVLET--RKIISGDPQNQQLRWEMAFNGSCSSICMWKSKNL
KGKFQFRVVAVNRLGFGDYSGASETITFPG--DDSWIPEMSL--TLLIIV--GVFLVITI
SLAFVWRKGFTNREAFKGALAVLACEDKELAELRGPMAGVGLANACYAVHTLPTQEEIQN
LPAFPREKLS

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRVLLGSGAFGEVYEGTAIDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFDHPNILKQLGVCLLNEPQYLILELMEGGDLLTYLRKARMTTL-RGPLLSLAH
LVDLCVDVSKGCVYLEQMRFIHR-DLAARNCLVSVKDYTSASRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPQGLWNLMAQCWAQDPDQRPAFRKIQTQLQL-FRN
FTLNDISQYRGDAGAHEVINEGFEDDDVR-ASSLSSD-GVMPVAFMVTTNQEGLNYMVLA
AEPSQSREHSEGPLCSKEPESCHL-RKAEKALPAGQDLCQEKRETGCR-SGTSPRLHYAF
LAHGGSGDGSDS

MKNIYWLILQL-----ANFATLGC-LWISMVECTVLNSCLKLCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKC-----------WESCEVGCSNAEGAYEEEVLENAD
LPTA-PFASSIGSYNMTLRWKSANFSGVKYIIQWKYAQFLGSWTYTKTVSKLSYVVKALH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIG

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKHQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----LDAIYYN
I---TGISVDVHQQIV-----YFSEGTFIWVKKATNMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLKNCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---GQCAEAVRIVESCTLKDFAI----N
PQS----KRIIYFNDTAQVFMSTFLDGSASHIILPHIPIA-DVKSFACENNDFLVTNGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGLSSQPHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIVELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNVSGTVMNVPELQSATKYKVSVRASSPKGPGPWSEPSTG--TTLVP----
--------ATEPPFIMAMKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISETYHLPGIAGAGVLAFEWLGHFLYWAGKTYVIQRQSMLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VAALTLDLSDGLLYWLVQDSQYIHLYTAVLRGQS-AEDTTIT
EFTAWSTSEISQNALIYYSGRLFWINGLKIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFHIRWNGPPAVDWGVVFYSVEFSAHSK
FLTSE--------QQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPKISLSLRAPET-VPS
APENSRIFILPSGKCCN

PF00041 // ENSGT00760000118818_6_Domain_4 (1518, 1614)

KNE-VVVEFRWNKPRHENGVLTRFKIFYKISSQS---------
---ITNETFEDWIAVNV---TPSVMSFQLEGMTPGCFVAFQVQAFTSKGPGPFSDILKST
TSEIKTFPYLITLLDNKIVFLDMDQNQVVWMFSAERVISAMGYT----ADNEMAYY----
AEGDSLFLLNLHNRSS---SELFRDSLISEIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYLREVK--ICNRNSTIISFSVYPLLS--RLYWTEVSDFGYQMFYYSIINHTLH
RILKPTATNQQSKSNQCSCNMTEFELSGPMAIDTSNLEKPLIYFAKA-QEIWATDLEGCQ
CWRVIMVPAMLA-GKTLVSLTVDGDFVYWIITAKDSTQIFQAKKGNGAIISQVKALRSKH
ILAYSSVMQPFPDKVFLSLASDTVEPTILNTTNTSLTIGLPLAKTNLTW-YGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQGSIALIEDLQPFSTYVIQIAVKNYYSDP
LEHLPPRKEIWGKTKSGVPEAVQLINTTVRSDSSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGSLTLLVTRLSGGNIYVLKV--LACHSEEMWCTESHPVTVKMFD
TPEKPDSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2249)

ENTSLQFNWKAPSNVNLIRFWFELQKWKY--NEFYNVKTSCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YKTGESST

ENSGT00760000118818_6_Linker_7_9 (2249, 2471)

SLPESFIT----KAGVPSKPGIPKLLEGNKNS
IQWEKAEDNGSRII----YYILEI--RKSTSNNSQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENILFVG-D-DFWIPETSF--ILTIVV--GIFLIVTI
LLTFVWHRRLKNQKRAREGPTVLINEDQELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSRFNHPNILKQLGVCLLNEPRYIILELMEGGDLLTYLRKARMAMF-YGPLLTLVD
LIDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLTDGIFTTHS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDNLWNLMIQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINKGFEGEDGN-VICLNSD-DIMPVALVETKNREGLNYMVLA
TECSQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPAGLNYAC
LTHSGYGDGSD-

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLENAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSRLSYVVKPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 304)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPGAESSITT-SSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAEAVRIVESCTLKDFAI----K
PQA----KRIIYFNDTAQVFTSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQTQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQKTSVSVLEPARFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYNISNQS---------
---ITNKTCEDWIAVNV---TPSVMSFQVEGMSPRCFIAFQVRAFTSKGPGPFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYT----ADNEMGYY----
AEGDSLFLLHLHNRSS---SELFQDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSNFGYQMFYYSIINHTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCQ
CWRVITVPAMLAG-KTLVSLTVDEDFIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSPASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVYYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKKIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPLNVNLIRFWVELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPNKPGIPKLLEGSKNS
IQWEKAEDNGCRIT----YYILEI--RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-D-DFWIPETSF--ILTIIV--GIFLVVTI
PLTFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLERMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANNSGVINESFEGEDGD-VICLNSD-DLMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-SGKTEGLNYAC
LTHSGYGDGSD-

MKNIYWLILKL-----ANFATLGC-LWISVVQCTVLNSCLKSCVTNLGRQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCNDTYTTVC--EWESCEVGCSSAEGAYEEEVLENAD
RPTA-PFASSIGSYNMTLRWKSANFSGVKYIIQWKYAQFLGSWTYTKTVSKLSCVVKALH
PFTEYIFRVAWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIG

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPNTVE
VSWDPPQFPGGPILGYNLRLISKHQKLDAGTQRTSFQFYSTLPNTIYR---FSVAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTFIWVKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVCVCDLKNCSNIEEITPPSI
STPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---TQCAEAVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHIILPHIPIA-NVKSFACENNDFLVTNGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQELSLL
FGSHQALVQWKTPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DPPEVTHIFLNVSGTMLNVPELQSATKYRVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYRLPSIAGAGALAFEWLGHFLYWAGKTNVIQRQSMLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSEKK----------
------------------VTALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-AEDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGLRIITTQEIGQRTSVSVLEPAKFNHFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFHIRWHGPPAVDWGVVFYSVEFSAQSK
FLTSE--------QQSSPVFTVEGLEPYASFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENSRIFVLPSGKCCN

PF00041 // ENSGT00760000118818_6_Domain_4 (1518, 1614)

KNE-VVVEFRWNKPRHENGVLTRFEIFYKISSQS---------
---ITNKTFEDWIAANV---TPSVMSFQLEGMTPGCFVAFQVQAFTSKGPGPFSDILKST
TSEIKSFPYLITLLDNKIAFLDMDQNQVVWMFSAERVISAMGYT----ADNEMGYY----
AEGDSLFLLNLHNRSS---SELFRDSVISEIT-VITIDWISRHLYFALKESQNGLQIFDV
DLEYKVKYLRKVK--ICNKNSTIISFSVYPLLS--RLYWTEVSDFGYQMFYYSIINHTLH
RILQPTATNQQSKRNQCSCNVTEFELTGAMAIDTSDLEKPLIYFAKA-QEIWVTDLEGCQ
CWRVITVPAML--GKTLVSLTVDGDFVYWIITAKDSTQIYQAKKGTGAIVSQVNALRSQH
ILAYSSVMQPFPDKVLLSLASDTVEPTILNTTNTSLTIRLRLVKTNLTW-YDITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQGSIALIEDLQPFSTYMIQTAVKNYYSDP
LEHLPPRKEIWGKTESGVPEAVQLINTTVRSDTILIISWRESHKPNGPKESVRYQLAVSH
LALIPETPLRQSEFPNGSLTLLVTGLSGGNIYVLKV--LACHSEKMWCTESHPVTVEMFD
TPEKPYSLLPE

PF00041 // ENSGT00760000118818_6_Domain_7 (2172, 2249)

NTSLQFNWKAPSNVNLLRLWFELQKWKY--NEFYHVKTSCS-QAPAYVC
NITDLQPYTSYN-VRVVVV-YKTGESST

ENSGT00760000118818_6_Linker_7_9 (2249, 2471)

SLPESFIT----KAGVPSKPGIPKLLEGNKNS
IQWEKAEDNGSRII----YYILEI--RKSTSNNSQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-V-DFWIPETSF--ILSIIV--GIFLTVTI
SLTFVWHRRLKNQKSAREGPTVLINEDQELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSRFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LIDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RTVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTHS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMIQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEAN-NGVINEGFEGDDGN-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECSQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LTHSGYGDGSD-

MKNIHWLILKP-----ASFVTLGC-IWISVVQCIVLKSCLKSCIMNLGLQLDIDTPFN--
-LSEACIQGCQFWSFVDQENCALKCR-----------ESCKAGCSSAEGAYEEEMLE---
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PVASSIGSHSVTLQWKSANISGVKYIIQWKYVQLQGSWTYTETMSKLLYVVKPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFRAQLQLYSPPSRTYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APSISNIESSSPNTVE
VSWVPPQFQGGPILGYNLRLISKNQKLHSGTQRTSFQFYSTLPNTTYR---FSVAAVNEV
GEGPEAVSGITT-PSTAVQEEEHWLFLSRKSSVRKRSLKHLVDEAHCLW----SDAIHHN
I---TGISVNFHQQIV-----YFSEGTLIWVKEVANMSDVSDLRIS--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSELISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMNELVYVCDLENCSNLEEITPLSL
ISPQKVVADSYNGYVFYLLRGGIYRVNLPGPA---GRDTNPVCIVESCTLKDFVV----K
PQS----KRIIYFNDTIQVFMSTFLDGSDSYFVLPEVPPA-NVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFTVGCDLSH----IEELGFGNLVIFGSSTQPHPLPGRPQELSVL
FGSHQALVQWKPLALAIGT------------------------SLSAWQNWTYEVKVSTQ
GIPEIIQVFSNISGTKLNVPDLQSATKYRVSVRASSPKGPGPWSEPSVG--TTLVS----
--------AAEPPLIMAVKEDGLWSKLLDSFDPAEFLSSDIGNVSDMDWYNNSLYYSDMK
GDVYVRLLNGI-DISTSYTPLNISGVGAFAFEWLGHFLYWAGKTYMIQRQSVLTGHTDIV
THVKLLVNDIVVDSIGGYLYWTTLYSVESTRLNGENPLVLQEQPWLSGQK----------
------------------VIALTLDLSDGLLYWMVQDSHCIHLYTAILRGQSTV-GVTIT
EIAFWSTSEISQNALMYYSGRLFWINGFKIITAQEIGQKSSVSISEPAGFNQFIIIQRSL
KPLP--GNFSSTLKVIPGSVQESSFRIEGRASSFQILWNAPSEVDWGIVLYSVEFSAHSK
VYSTT--------ISNTE------------------------------------------
------------------------------------------HLYQSIY-----------
------------------------------------------------------------
---------------NELYF-----------------------------------F----
HYP-TALLIHF-------------------------------------------------
---------NCWK--YC-----------SSPYS--RLYWTEVSNLGHQMFYCSIINHTLH
QVLQPMSANQQNGRRQCYCNVTEAELSGAMAIDTSDLEKPWIYFTKG-QEIWVMDLEGCQ
CWTVIIVPVL----KTLESLTVDGDFIYWIITGKDNTEIYQAKKSNGAILSQVKTLRSKH
ILAYSPVIQPFPDKAYLLLASDIIEPMILNASNTSLTLRLPPVKTNLTW-HCITSSTPTY
LVYYSEVNGSTHSSG---LKYRV-----LESQENIALIGGLQPFSTYIMQIAVKNYYSSP
LEHLPLGKKIWGKTKSGVPGAVGLINTTVLSDTSLHVSWKESQEPNGPKESVRYQLRLSH
LTPIPETPVRQSEFPSSRLAVIVTRLSGGQLYVLK--VLACHSEEMWYAESFPVTVKMFD
MPMKPYILVPGNTSLQLGWKAPLNVNLIRFWFELQKGKY--NEFYHVEASCS-QGPAYVC
NITDLQPYISYS-VQVVVV-YMTGESSASLPESFKT----KVGVPSKPGIPKLLERSKNS
IQWAKAEDNGSRLT----YYILEI--RKVISNDSWNQNLRWKMAFNGSCNSICTWKSKTL
KGTFQFRVVAANNIGFGEYSGVSENLILV--EDDLWIPETSF--IFTIVV--GIFLVAII
PLTFVWHRRLKSQKHSKEGLTVLINEDRELAKLQSLAAGVGLANACCAVHTVPTQEEIEN
LPIFPRENLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2753)

LHLLLGSGAFGEVYKGIAVDILGGGSGDIKVAVKTLKKGSTEQEKVEFLK
EAHMMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLSYLRKARRTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DIWSFRILAWEILTLGHQP
YPAHSNLVVLNYVQAGGRLEPPRRCPHHLWNLLTQCWAQEPDQRPTFHKIQDQFQL-FSN
VSLNTIPKSTEETNTMGVINEDFGDD---NMASMNSG-DFLQVALMETKNPEGLSYMVLA
TEGRQGEENSEGPLGSKESGSYGL-RKEKKEPDADQDFCQE-QVAYCP-SDRTKGLNYAC
LTHSGHGDGSD-

------------------------------------------------------------
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------------------------------------------------------------
--------------------YT-----SNISITISSFH-LIAGVPSKPGTPKLLEGSENS
IHWEQAEDNGSRLL----YYILEI--REGTANDSQKQNVRWKMAFNGSCSSICTWKSKNL
KGTFQFRVAAANNLGFGEYSGISENILLAGALDGFWIPETSF--ILVIIV--GIFLVVII
PLAFVWHRRLKNQKTSKEGLTILINEDKELAELRGLGTGVGLANACYAIHTLPTQEEIEN
LPTFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LVDMCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMTQCWAQESDQRPSFHKIQDQLQL-FKK
FSLNCISQCRDEGNIGGVINEGFEGEDVS-MICLSSDDDVRPIALMETKNQEGLNYMVLA
TECSQREENSEGPLGSKESESCGM-RKEEKEPHADRDFCQEKQVAYCP-PGKAEGLNYAC
LTHSVYGDGSD-

MKNIYWLILKL-----VKFATLGC-IWISVMHCTVLNSCLKSCVVNLGRQLEIGTPYN--
-LSEPXXXXXXXXXX---------XXXXXXXXX--XRESCEVGCSSAEGAYEEEVLEN

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

AD
LPTA-PFASSIGSHHVTLRWNAANISGIKYIIQWKYTQLPGSWTYTKAVSKLSYVVEPLH
PFTEYIFRVVWIFMAQQQLYSPP

ENSGT00760000118818_6_Linker_0_1 (204, 222)

SPSYRTH-P------HGV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKTQKLDSGTQSTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESSITT-SSPAVQEEEQWLFLSRKSSLRKRSLKHLVEEAHCLH----SDAIRYN
I---TXXXXXXXXXXXXXXXXX--------------------------------------
--------------------------------------------------------X---
---------X-----X-----X------X-----X-----X------X-----X-----X
-----X------X-----XX----X------XX----X-----X-----X------X---
--X-----X------X-----X-----X-----X------XX----X-------------
------------------------------------------------------------
-------------------------XXXXXXXXXXXXXXXVCVCDLENCSTIEEISLPSN
IAPQKIEADSYNGYVFYLQRDGIYRADLPLPP---GRDFETVRIVASYTLKDFVV----K
PQS----KRIIYFNDTARVFMSTFLDGSASHLVLPHVPFA-EVKSFACENSHFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSR----IEEFGFGNLVIFGSSNQPHPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGRPQQLSVL
FGSHQALVQWKPPALAIGANVVLF-------------YIALFLGPSAWQNWTYEVKVSTQ
DLPEITHFFSNISGTMLNVPKLQSSTKYKVSVRASSPKGPGPW

ENSGT00760000118818_6_Linker_2_3 (1064, 1397)

SEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSEIGNVSDMDWYNNSLYYSDMK
GDVYVWLLNGT-DVSENYHISNIAGAGALAFEWLGHYLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLTLQAQPWFSGKK----------
------------------VXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXIGDTTIT
AFAAWSTSEISQNALMYYSGRLFWINGVRIITAQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFAPKVI

PF00041 // ENSGT00760000118818_6_Domain_3 (1397, 1487)

PDSVQESSFRIEGNASSFQILWNAPPAVGWGVIFYSVEFSAYSK
FLATE--------QQPLPEFTVEGLEPYALFNLSVTPYTYWGKGPKTSLLLRAPEA-VPS
APENPRIFILPSGKYSNKNE-VVVE-IWNKPKHENGVLTRFEIFLSXXXXX---------
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIRVFTSKGPGPFSDIAKSK
TSAIDPFPYLITLFGNKIAVLDMDRNQVVWTFSAERDISVVGYT----ADNEMGYY----
AQGDSIFLLNLHSHSS---SEXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXQ
CWRVIMVPVML-AGKTPVSLTVGGNFLYWIVTEKDSTQIYQAKKKNGAIPSQVKAPKSEH
ILSYP-LMHPFPYKAFLSPASDAEEPTILNATNTSLTIELPPVRTKLTW-SGITSPTPTY
LVYYREVNSKKNSSD---LKYGM-----LEFQERIAFFEGLQPFSTYMIQIAVKNYYSDP
LEQLPLGEEIWGKTKSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX-XXXXXXX
XXXXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXXXXXX-XXXGVPSKPGIPKLVEGSKNS
IQWEKAEDHGSRIM----YYILEI--RKGTSNDSQNQNSQWKVAYNGSCSSICTWKSKNL
KGTFQFRVIAANKLGFGEHSGISENIVLVG--DAFWVPETSF--IFTIII--GIFLIFTI
LLTFVCHRRLKNQKTPKEGLSVLINEDKELAELRDLA-TVGLASACYAIHTLPTQDEIES
LPTFPREK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LTLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFDHPNILRQLGVCLLNEPQYIILELMEGGDLLTYLRRARKTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLTYVQTGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHKIQDQLQL-FRN
FSLNSISQCSDKANTCGVVNEGFEDEDVN-VKCLNSD-DVIPIALVETKNQEGLNYMVPA
TECHQGEQNSEGPLGSKGSEPCGL-GKEEKEPHADKDICQEKQVAPCPSPGTPGGLNYAR
LTHSGNGEGSD-

MKNIYCLILKL-----VNFATLGC-LWIFVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSTAAVNEV
GEGPEAQSSITT-SSSAGQEEEQWLFLSRKTSLRKRSLKHLVDEAYCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GQCAEAVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASRLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGANV----------ILTGDIIEPFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFSNISGTMLNVPELQSATKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------RHSLPVFTVEGLEPHALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPEHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVNV---TPSVMSFQLEGMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKKSQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINRTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAIDLEGCH
CWRVITVPAMLAG-KTLASLTVDGDFIYWIITAKDSTQIYQAKKGNGVIVSQVKALRSRH
ILAYSSVMQPFPDKVFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVFYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYRIQIAVKNYYSDP
LEHLPPGREIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPSKPGIPKLLEGNKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSRNL
KGVFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLVDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINESFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECSQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LTHTGYGDGSD-

MKNIYWLILKL-----ASFATLGC-LWISVVQCTVLNSCLKSCVTNLGRQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKC-----------WESCEVGCGSAKGAYEEEVLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSYNMTLRWKSANISGVKYIIQWKYAQFLGSWTYTKTVSKLSYVVKPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIFTEQLQLYSPPSPSYRTH-P------HGVPETAPLIG

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKHQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTFIWVKKGTNMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLKNCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---GQCAEAVRIVESCMLKDFAI----K
PQS----KQIIYFNDTAQVFMSTFLDGSASHIILPHIPVA-DVKSFACENNDFLVTNGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQPHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILTSDIVELFELGPSAWQNWTYEVKVSTP
DPPEVTHIFLNVSGTMLNIPELQSATKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIVNVTDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSMLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VTALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-AEDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGLRMITTQEIDQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFHIWWNGPPAVDWGVVFYSVKFSAHSK
FLTSE--------QQSSPVLTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-V--
------------------------------------------------------------
------------------------------------------QAFTSKGPGPFSDFLKST
TSEIKPFPYLITLLDNKIVFLDMDQNQVVWMFSAERVISAMGYT----ADNEMGYY----
AEGDSLFLLNLHNRSS---SELFRDSLISEIT-VITIDWISRHLYFALKESQNGMRIFDV
DLEHKVKYLREVK--ICNRNSTIISFSVYPLLS--RLYWTEVSGFGYQMFYYSIINHTLH
RILQPTATNQQSKRNQCSCNVTEFELSGAMAMDTSNLEKPLIYFAKA-QEIWATDLEGCQ
CWRVITVPAMPA-GKTLVSLTVDGDFVYWIITAKDNTQIFQAKKGNGAIVSQVKALRSKH
ILAYSSVMQPFPDKLFLSLALDTVEPTILNTTNASLTIRLPLAKTNLTS-YGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQGSIALIEDLQPFSTYMIQIAVKNYYSDP
LQHLPPRKEILGKTKSGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAILN
LALIPEAPLRQSEFPNGSLTLLVTRLSGGNTYMLKV--LACHSEEMWCTESHPVTVEMFD
TPEKLYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2249)

ENTSLQFNWKTPSNVNLIRFWFELQKWKY--NEFYHVKTSCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YKTGESST

ENSGT00760000118818_6_Linker_7_9 (2249, 2471)

SLPESFTT----KAGVPSKPGIPKLLEGNKNS
IQWEKAEDNGSRII----YYILEI--RKSTSNNSQNQDLRWKMTFNGSCSSICTWKPKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-D-DFWIPETSF--ILTIIV--GIFLIVTI
SLTFVWHRRLKTRKSAREGPTVLINEDQELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSRFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-YGPLLTLVD
LIDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTHS----------DVWSFGILIWEILTLGRQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMIQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTNGVTNEGFEGEDGN-VICLNSD-DIMPVALMETKNREGLNYMVLA
TERSQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKSEGLNYAC
LTHSGYGDGSD-

MKNLHWLSLKL-----VSFATLGC-IWISVGQCTVLNSCLKSCVTNLGRQLDVGTPHN--
-LSEPCIQGCHFWNSADQENCALKCNETYAAVC--ERESCEVGCSSGEGAYEEEVLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGMTLRWKSANISGVKYIIQWKYTQLPGSWTYTEAVSKLSYVVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-PSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----SDATHHN
I---TGISVNVHQQVV-----YFSEGTLIW------------------------------
-------------------------------------V-----K------D-----A---
--A------N-----M-----S------D-----V-----S------G-----L-----R
-----I------F-----Y-----R------G-----S-----G-----L------I---
--S-----S------I-----S-----I-----D------W-----L-----Y------Q
-----K-----M------Y-----F-----------------------------------
-----------------------------------IMDELVCVCDLENCSNIETITPPSI
IAPQKIVADSYNGYVFYLLRDGIYRVNLPVPS---GGGSEAMRIVQSGTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHIILPHVPFT-NVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSYTQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQQLSVL
FGSHQALVQWKPPTLAIGAS------------------------PSAWQDWTYEVKVSTQ
DLPETTHVFSNISGTILNVHDLQSATKYEVSVRASSPKGPGPWSEPSVG--TTLVPD---
------QTAAEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMK
GDVYVWLLNGT-DISENYQIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGCTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESPLVLQAQPWFSGKK----------
------------------VIALTLDLSDGFLYWLVQDSQCIHLYTAVLRGQSSAGDTTIT
EFAAWSTSDISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIVQTSL
KPLP--GNFSFTPKVIPDAIPESSFMIEGNASRFHILWNAPAAVDWGVIFYSVEFSAHSK
FLASD--------QQSKPVFTVEGLEPYALFNLSVIPYTYWGKGPKTSLSLRTPET-VPS
APENPRIFILPGEKHCNK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1614)

NE-VVVEFRWNKPQHENGVLTRFEIFYQISNQN---------
---DTNRTVEDWLAVNV---TPSVMSFQLEGVSPGYSVAFQVRVFTSKGPGPFSDIVKSK
TSEINPFPYLITLADNKITLLDMDRNQVAWTFLAEGDVAAMGYT----ADDAVGYC----
AQGDSLFLLRMDNRSS---TKIFSDALVFDIT-FITIDWISRHLYFVLKESQSEMQIFDM
DLENKVKYPRKLK--VCNRNSTITSFSVYPFLS--RLYWTEVFDSGSQMFYYSIMNQTVH
RILQPPVINHPN-GSQCSCNVTESELSGAMTIDTSDLKKPQIYFVKG-QEIWATDLESCQ
CWQVIILPAPL-AGKMLVSLTVDGEFLYWISKAEDSTQIYQAKKSNGAILSQVEAPRSKH
ILVYSSVLQPFPDRAFLSLASDIAEPTILNTTNTSLTIRLPPARTKLTW-DGITGPTPTY
LVYYKEVIDMKNSSE---LRDKM-----LEFQESIAFIEGLQPFSTYMIQIAVKNYYSDP
LEQIPLGKEIWGKTKSGVPEAVWLINTTVQSDTSLVISWRESHKPNGPRESVRYQVAISH
LAPIPEIPLRQSEYPDGSLSLLVTRLSGGKLYVLK--VLACHAEEMWCAESHPVTVETFD
SPEKPYAFLPENTSLQLHWNAPSNVHLIRFWFELQKWKH--NEFYHVKASCS-RGPAYVC
NVTDLQPYASYN-VRAVVM-YRTGANSTSLPGSFKTKV-SKAGVPSKPGIPKLLEGSKNS
IQWEKADDNGSRLM----YYILEI-SRKSTSNDSQNQNLTWKMAFNGSCNSICTWKSKNL
KGTFQFRVVAVNNLGFGEYSGISEDIILVG-VDGFWIPETSF--ILTIII--GIFLVISI
PLIFVWH-RLKNQSTPKEGLTVLINEDKELAELRSLATGVGLANACYAIHTLPTQEEIES
LPAFPREKLTLRL

PF00069 // ENSGT00760000118818_6_Domain_9 (2474, 2752)

LLGSGAFGEVYEGTAIDILGAGSGETEVAVKTLKKGSTDREKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTPF-HGPLLTLVD
LVDLCVEISKGCVYLEQMHFIHR-DLAARNCLVSMKDYTSPSRTVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHKVQEQLQL-FRK
FSLNSISQCRGEANPSGVINEGFEDEDGH-PICLNSD-DVTSVALMETKNQEGLNYMVLA
TECRQGETNSEGPLGSKESESCGL-RKEEKEPHADIAICQEKQVAYCP-PGKPGGLNYAC
LTHSGYGDGFE-

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCNDTYATIC--ERESCEVGCSSAEGAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTMYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAETVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQPHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DPPEVTRIFSNISGTRLNVPELQSAMKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWQLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVDV---TPSVMSFQLEDMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINCTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFTKA-QEIWAMDLEGCH
CWRVITVPAML-G-KTLASLTVDGDFIYWIITAKDSTRIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-YGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
APEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPGKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECSQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

MKNVYWLSLKL-----VNFATLGC-VWISVVQCTVLNSCLKSCVTNLGRQLDVGTPHN--
-LSEPCIQGCHFWNSADQENCALKCNETYAAVC--ERGGCQGNCLSSKGSYSLLFFKNAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGMTLRWKSANISGVKYIIQWKYTQLPGSWTYTEAVSKLSYVVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNIESSSPDSVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-PSPAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLQ----SEATHHN
I---TGISVNVHQQAV-----YFSEGTLIW------------------------------
-------------------------------------V-----K------D-----V---
--A------N-----M-----S------D-----V-----S------G-----L-----R
-----I------F-----Y-----R------G-----S-----G-----L------I---
--S-----S------I-----S-----I-----D------W-----L-----Y------Q
-----K-----M------Y-----F-----------------------------------
-----------------------------------IMDELVCVCDLENCSNIETIAPPSI
IAPQKIVADSYNGYVFYLLRDGIYRVDLPVPS---GGGSEAMRIVQSGTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHIILPHVPFT-NVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSYTQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQQLSVL
FGSHQALVQWKPPTLAIGAS------------------------PSAWQDWTYEVKVSTQ
DLPETTHVFSNISGTVLNVHDLQSATKYEVSVRASSPKGPGPWSEPSVG--TTLVPD---
------QTAAEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMK
GDVYVWLLNGT-DVSENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESPLVLQAQPWFSGKK----------
------------------VIALTLDLSDGFLYWLVQDSQCIHLYTAVLRGQSSAGDTTIT
EFAAWSTSDISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIVQTSL
KPLP--GNFSFTPKVIPDAIPESSFMIEGNASRFHILWNAPPAVDWGIIFYSVEFSAHSK
LLASE--------QQSKPGFTVEGLEPYALFNLSVIPYTYWGKGPKTSLSLRTPET-VPS
APENPRIFILPSEKHRNKNV-VV

PF00041 // ENSGT00760000118818_6_Domain_4 (1524, 1614)

VEFRWNKPQYENGVLTRFEIFYQISNQN---------
---DTNKTVEDWIAVSV---TPSVMSFQLEGMSPGYSVAFQVRVFTSKGPGPFSDIVKSK
TSEINPFPYLITLVDNKIALLDMDRNQVTWTFSAEGDVGAMGYT----ADDAVGYC----
AQGDSLFLLRMDNRSS---TEIFRDALVFNIT-FITIDWISRHLYFVLKESQNRMQIFDM
DLENKVKYPRKLK--VCNRNSTITSFSVYPFLS-SRLYWTEVFDSGSQMFYYSIINKTVH
RILQPPVINHPN-GSQCSCNVTESELSGAMTIDTSDLKKPQIYFVKG-LEMWATDLEACQ
CWQVFILPVPL-AGKMLVSLTVDGEFLYWISKVEDSTQIYQAKKSNGAILSQVEAPRSKH
ILVYSSVLQPFPDRAFLSLASDIAEPTILNTTNTSLTIRLPPARTKLTW-DGIISPTPTY
LVYYKEVIDMKNSSE---LREKM-----LEFQGSIALIEGLQPFSTYMIQIAVKNYYSDP
LEQIPLGKEIWGKTKSGVPEAVWLINTTVQSDTSLVISWRESHKPNGPRESVRYQVAISH
LAPIPEIPLRQSEYPDGSLSLLVTRLSGRKLYVLK--VLACHAEEMWCAESHPVSVETFD
SPEKPYAFLPENTSLQLHWKAPSNVHPIRFWFELQKWKH--SEFYHVKASCS-QGPAYVC
NITDLQPYASYN-VRAVVV-YRTGANSTSLPGSFKTKV-SKAGLPSKPGIPKLLEGSKNS
IQWEKSDDNGSRLM----YYILKV-NRKSTSNDSRNQNLTWKMAFNGSCNSICTWKSKNL
KGTFQFRVAAVNHLGFGEYSGISEDITLVG-VDGFWIPETSF--ILTIII--GIFLVITI
PLIFVWH-RLKNQSTPKEGLTVLINEDKELAELRSLATGVGLANACYAIHTLPTQEEIES
LPAFPRGKLTLRL

PF00069 // ENSGT00760000118818_6_Domain_9 (2474, 2684)

LLGSGAFGEVYEGTAVDILGVGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTPF-HGLLLTLVD
LVDLCVEISKGCVYLEQMHFIHR-DLAARNCLVSMKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGDGLLPVRWMAPESLMDGIFTTQS----------DVW----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------

MKNIYWLILKLVSLQLVSFATLGC-IWISVVQCTVLNSCLKSCVTNLGRQLDIGMPYN--
-LSEPCIQGCHFWNFVDQENCALKCR-----------ESCEVGCSSSEGAYEEEVLEN

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

SD
LPTA-PFASSIGNRSVTLRWKSANISGIKYIIQWKYTHLLGSWTYTEAVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPP

ENSGT00760000118818_6_Linker_0_1 (204, 222)

SPSYRTH-P------YGV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESNITT-SSSAVQEEEQWLFLSRRTSLRKRSLKHLVDEAQCLQ----SDVIHRN
I---TGISVNVHQQVV-----YFSEGTLIW------------------------------
-------------------------------------M-----K------E-----A---
--A------N-----M-----S------D-----M-----S------D-----L-----R
-----I------F-----Y-----R------G-----S-----G-----L------I---
--S-----S------I-----S-----I-----D------W-----L-----Y------Q
-----R-----M------Y-----F-----------------------------------
-----------------------------------IMDELVCVCDLENCSNIEEITPPSI
IAPQKIVADSYNGYVFYLLRDGIYRVDLPVPF---GQDSEAVRIVESCTLKDFAV----K
PQS----KRIIYFNDTAQVFTSTFLDGSASHLVLPHVPFA-DVKSFACENNDFLVTDGKA
VFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFSTYTQPHPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGRPQQLSVL
FGSHQALVQWKPPDLAIGANI----------ILLSNII--LFLGPSAWQNWTYEVKVSTQ
DFPEITRVFSNISGTMLNVPKLQSATKYRVYVRASSPKGPGPWSEPSVG--TTLVP----
--------AIEPPFIMAVKEDGLWRKPLNSFGPGEFLSSDIGNVSDMDWYNSSFYYSDMK
GDVYVWLLNGT-DISENDRIPNIAGAGALAYEWLGHFLYWAGRTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VVALTLDLSDGLLYWLVQDSQCMHLYTAVLRGQN-AGDITIT
EFAAWSTSEISQNALMYYSGRLFWINGYRIITAQEIGQRTSVSVLEPAKFNQFTIVQTSL
KPLP--GNFSFTPKVIPDSIQESSFKIEGNASSFQILWNAPPAVDWGVIFYSVEFSAHPK
FLASE--------QQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRVFILPSGKYRNKNK-VVVEFRWNKPKYENGVLTRFEIFYQISKQN---------
---DTNKTFEDWIAVNV---TPSVMSFQLESVSPGYIVAFQVRVFTSKGPGPFSDIVKSK
TSEISPFPYLMTLFGNNIVLLDMDQNQVVWMFSAERNISAVGYT----ADNAMGYY----
AQGDSLFLLNMDNQSS---SEIFRGALIFDIT-TITIDWISRHLYFVRKESQNGMQIFDV
DLERKVKYPRKLK--ICNRNSTIISFFIYPLLS--RLYWTEVSDLGSQMFYYSIINQTLH
HILKHTAINHSNGRNQCSCNVTEFELSGVMTIDTSDVRKPRIYFVKG-QEIWATDLEGCH
CWQVIVVPVLF-AGKSLVSLTVDGEFLYWISVVKDSTQIYQAKKSHGAILSQAKALRSEC
ILAYSSVLQSFPDKAFLSLASDIAEPTIVNTTNTSLTIRLPPTRTKLTW-YGITSPTPTY
LVYYKEIGSRNNSSE---LKYRM-----LEFQENIALVEGLQPFSTYVIQIAIKNYYSDP
LERLPLGKEILGKTKSGVPEAVWLINTTVQSDTSLIISWRESHKPNGPKESVRYQLAISH
VALIPKTPLRRSEYPNGRLSLLVTRLSGGKLYVLK--VLACHAEEMWCAESHPVTVEMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2253)

PEKPYALVPENTSLRLDWKAPSNVNLIRFWFELQKWRY--NEFYYVNASCG-QGSAYVC
NITDLQPYTSYN-IRVVVL-YRTGENSTSLPE

ENSGT00760000118818_6_Linker_7_9 (2253, 2469)

SFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAYDNGSRLK----YYILEI--RKYTSNDSQNQNLMWKMAFNGSCNSICTWRSKNL
KGTFQFRVVAANNLGFGEYSGISENIMLAG--DGFWIPETSF--ILSIII--GIFLVVIM
PLIFV-HRRLKNQKTPKERLTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIES
LPAFPREK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2756)

LTLRLLLGSGAFGEVYEGTAVDILGVGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMKAF-RGPLLTLVD
LVDLCVDISKGCVYLEQLHFIHR-DLAARNCLVSVKDYSSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLIDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRHCPDDLWNLMTQCWAQEPDQRPTFQKIQDQLQL-FRN
FLLNSISQYREEANPSGVLNEGFEDENGN-MICLNLD-DGTSIALMETKNQEGLNYMVLA
TECSQGEDNSEGPLGSKESESCGL-RKEEKEPHADKGICQEKQVAYCP-PGKPESLNYAC
LTHSGYGDGSD-

MRNTCLWDYPL-----NRLATFYF-VWISAVYCTFSKNCQNLCTSNLEGELGIANLCNVS
DINGACTQGCQFWNATVQLSCPLKCNKTYTRAC--ETISCKFGCSRAEDAYGVEAQEY

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

LN
NPGA-PFASTIGSHNVTLGWKPANISEVKYIIQWKFNQLPGDWRYTEVVSETSYTVKDLQ
AFTEYVFRVVWIITSQLQLHSPP

ENSGT00760000118818_6_Linker_0_1 (204, 219)

SPSYRTHA-------

PF00041 // ENSGT00760000118818_6_Domain_1 (219, 306)

FGAPTTAPIIKDIQSSSPNTVE
VSWSPPLFPNGLIIGYNLLLTSENHKLLRASRGHSFQFYSTFPNSTYR---FSIVAVNEA
GAGPP

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AEANITTPESKVVKEKAKWLFLSRNQSLRKRYMEHFLEAAQCLP----SGIIHHN
I---TGISVNVYQQVV-----YFSEGNSIWVKGAADMSDTSDVMLF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YAGRGNITSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RIYFVMNEKIHVCHLENCTAAEDITPLYV
TSPRKVVADPYNGYIFCLLEDGIYRANLPPFP---DTASAASLVVKSSALRDFVI----N
FQS----KRLIFFNKTEQAFVSGFLDGSEFHMLRSHVTLD-DMESFVYEDNMFTVTDGWA
VFQEEVSPDGKSSFNEYVVDCSLDF----PEYSGFGNLLFYGASTQPFPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PTPPRFVTVL
FGLHQAVISWRSPEHTIGTS------------------------PSAWQNWTYDVKVSSQ
NPSEEEQVISNISDTRFMVKKLASFTAYEMSVRAVSPAGEGPWSESFRG--MTLDE----
--------AEEEAYILAVGAEGLWRQWLDTYGPGEFLSPNIRNISDLDWYNGTLYWSNSM
GKVQAWSLNKRESTAENPYISDIRNARMLAFDWLGQCLYWAGKANTIYRKSLLGGHMDVV
AHVVYLVKDLVVDSVNGYLYWATMYSVESARLNGEEYLLLQEQLQFSGKQ----------
------------------VVGLALDVSHGFLYWLVQESLCLNLYRISLCKEG-CGNVIVT
EFAAWSISETSQSTLEYYSGRLFWINNLQFITTQEVNQSISIPFSEPAKFAAFTLVHTSL
KPLP--GNFSFTPKVIPNAVPVSSFRIKGNSSSFTIVWSASANVEWGTVFYCVGSKALQ-
SQSLENEQCLQPHNLTVPSYQVDWLEPFELFDFSVTPYTYWGKAPTTSVFLRAPEGAV

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APTNPRIYVLHNNLHEGEEK-IHVEFRWNKPERDNGVLTHFRVYYQQLCQN---------
---DTADTLMEWNVSNV---KHNVLLFSLRDVLPHLTVRFQVQAFTSVGPGPLSDIVQRN
SSDLFPVPTLITVSANKLFLTDIDNNHTIWELLAKTNIKDICYT----ANDDTMYY----
ILEDSLFLLNIQTTSV---FQFFKDAFLHNVT-AITVDWIARHLFVALKTSWNETQIFVI
DLELKKKSLQALNVQLGKHNSTVSSLLSYPLLS--RLYWMEELDYGSRMFYYDILNNTVQ
HILGYISAE-EQMRNYCSCNVTEAELGRSMSMDVSDSKNPQLLFIRGRDEIWASDVDGCH
CWRLTRIPSIQ--DKKIGSLTVDKQFLYWSIETKKYTEIYLANKETTRHSLQMKTNHELK
ILAYSTAMQSYPDKSCLIPLLDTEKPSILDITNTSFTVSLPSVTPQQLC-PGISQPTPTY
LVFLREMTNNTRNSS---YRLSTLQQKTLEFQGPIDVIDNLQPFSSYVIQVAVKNYYSDH
E-ELAMGKETIGTTLYGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2146)

PEAVDSVKAVVLSDTTINISWSEPLKPNGPLESIRYQISVNF
LSPFPATPLRKSEFPNGTLAWSVTGLQSGTNNLFK--VLAFHPNE

ENSGT00760000118818_6_Linker_6_7 (2146, 2162)

NWFSESVPVTAKTFE
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2250)

PPAPVNIFPRNTSFQLEWQAPLHVNGTSFWFELRKWQ-KSDWFSPASTTCSTAGLIYTC
NLTGTLPSTNYL-VRATVV-YVTGVKSTS

ENSGT00760000118818_6_Linker_7_9 (2250, 2469)

SSTIFKTTGLVKAGVPSKPGTPKRAENTQNS
VQWEKAEDNGSNLT----YYILESRKQT---DSTNKMKSLWVVVYNGSCASICTWKAKNL
EGTFQFRAAAANMLGLGEYSDTSKDIVLSK--DTVTYPDI--IDTVAVIGAVVLGLCMVM
LFGFVWYQRRKSTKPSLIGQIVLVKEDKELAQLRGMAEAVGLANACYAVSILPSQAEIDL
LPAFPRDK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LNLHKLLGSGAFGEVYEGTAVDILADGSGETKVAVKTLKKGATDQEKSEFLK
EAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLGYLRGARKQKL-QSSLLTVTD
LLDICLDICKGCVYLEKMHFIHR-DLAARNCLVSEKGYESCSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLIDGVFTNRS----------DVWSFGVLMWETLTLGQQP
YPGLSNMEVLHHVQSGGRLESPSNCPDDLCDLITRCWAQEPQNRPTFFYIQDKLQE-IRH
SPLCFNHCLEDKEAATGIINQAFE--GDV-VPKADSD-SILSTTLMETRDQEGLNYLVVV
KDSDQDQGSIN-------SEELSS-V----------------------------------
------------

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCR-----------ESCEVGCSSAEGAYEEEVLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHNMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSRPSYVVKPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSIAAVNEV
GEGPEAESSITT-SSSAVQQEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPQKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAEAVRIVESCTLKDFAI----K
PQA----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQALVQWKPPALAIGANV----------ILISDIIELFELGPSAWQNWTYEVKVSTQ
DPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGT-DISENYHLPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQTQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQKTSVSVLEPARFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYNISNQS---------
---ITNKTCEDWIAVNV---TPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGPYADVVKST
TSEINPFPHLITLLGNKIVFLDMDQNQVVWTFSAERVISAVCYT----ADNEMGYY----
AEGDSLFLLHLHNRSS---SELFQDSLVFDIT-VITIDWISRHLYFALKESQNGMQVFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSNFGYQMFYYSIISHTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCQ
CWRVITVPAMLAG-KTLVSLTVDGDLIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTNLTW-YGITSPTPTY
LVYYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPLNVNLIRFWVELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPYTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPNKPGIPKLLEGSKNS
IQWEKAEDNGCRIT----YYILEI--RKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG-D-DFWIPETSF--ILTIIV--GIFLVVTI
PLTFVWHRRLKNQKSAKEGVTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLERMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYKSRDEANNSGVINESFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-SGKPEGLNYAC
LTHSGYGDGSD-

MKNVYWLILKL-----FTFATLGC-IWISVVHCTVLNSCLKSCVNNLGRQLETGTPYN--
-LSEPCIQGCHFWNSVDQEKCALKCNDTFATIC--ERESCEVGCSSAEGAYEEQTLENAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHHVTLRWNAANISGIKYIIQWKYTQLPGSWTYTEAVSKLSYVVEPLH
PFTAYTFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLQLYSPPSPSYRTH-A------HGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLTSKTQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSITT-SSLAVQEEEQWLFLSRNSSLRKRSLKHLVDEAHCLP----SNATHHD
I---TGISVNVQKQVV-----YFSERNLIWVKAAANMSDVADLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSTVEEITLPSI
IAPQKIVADSYNGYVFYLLRDGIYRADLPVPS---ERGSEAVRVVESCTLKDFVV----K
PQS----KRIIYFNSTAQAFMSTFLDGSASHLVLPHVRFA-DVKSFACENSHFLATDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSTTQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQELSVL
FGSHQALVQWQPPALAIGA------------------------SPSAWQNWTYEVKMSTQ
DFLETTQFFSNISGTMLNVPELQSSTKYKVSVRAISPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLFYSDMK
GDVYVWLLNGT-DVSENYHISNIAGAGALAFEWLGHYLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLTLQEQPWLSGKK----------
------------------VIALTLDFSDGLLYWLVQDSQCIHLYTAVLRGQN-IGDTTIT
AFAAWSTSEISQNALMYYSGRLFWINGLRIITAQEIGQRTSVSVLEPARFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASRFQILWNAPPAVEWGVIFYSVEFSAPSK
FLASE--------QQSLPVLTVEGLEPYALLTLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFILPSGKYG

PF00041 // ENSGT00760000118818_6_Domain_4 (1517, 1614)

NKNE-TVVEFRWNKPKHENGVLTRFEIFYQISNQS---------
---DTNKTFKDWIAVNV---TPSVMSFQLEGMSPGYIICFQVRVFTSKGSGPFSNIEKAN
TSVINPVPYLITLFGNKITFLDMDQNQVVWMFSGERDIRAVGYT----ADNEMGYY----
AQGDSLFLLNMQSHSS---SELFRDALVFDIT-VMTVDWISRHLYFVLQESQNGMQIFDV
DLECKVKYPRLLK--IGNRNSTIISFSVYPFLS--RLYWTEVSNFGCQMFYYSIINQTLH
QILQTITTNHQNGRGQCSCNVTEFELSGAMTIDTSDLKKPCIYFVKG-QEIWAMDLEGCM
CWRVIMVPAML--GKT-TSLTVDRKFLYWIVTEKDSTQLYQAKKRNGAIPSQVKASMSEH
IVAYSPVMQPFPDKVFLSPASNTEEPTILNATNTSLTIGLPPVSPRLPW-FGISNPTPTY
LVYYREVNGTKNGSD---LPYRM-----LEFQDRRALIEGLQPFSTYMIQIAVKNYYSDL
LEQLPLGKEICGTTKSGVPGAVWLINTTVWSDTSLIISWREPHKPNGPKESIRYQLAISH
LPLIPATPLRQSEFPSGRLTLHVTGLSGGKLYALKKKVLACHSEEMWCAESRLVTVEMFD
TPE

PF00041 // ENSGT00760000118818_6_Domain_7 (2164, 2246)

KPYALVPENTTLQLEWKAPSNVNLIRFWFELQKWKY--TEFYRINGSCS-PGPVYMC
NITDLQPHTSYN-VRIVVV-YVTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2474)

NSTSLPESFKTKV-SKAGVPSKPGIPKLLEGSKNS
IQWEKAEDHGSRIM----YYILEM--RKGTSNDSKNSSLWWKTAFNGSCSSICTWKSKNL
KGTFQFRVVAANNLGFGEHSGISDNIIL-A-EDAFWVPEISF--IFGIII--GIFLIVTI
LLAFLWHRRLKNQKTPKEGLAVLINEDKELAELRGLAAGVGLASACYAIHTLPTQDEIES
LPTFPREKLTLRL

PF00069 // ENSGT00760000118818_6_Domain_9 (2474, 2752)

LLGSGAFGEVYEGTAVDILGVGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFDHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRRARKTTF-HGPLLTLVD
LVDMCVDISKGCVYLEQMPFIPR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLTYVQTGGRLEPPRNCPNDLWTLMSQCWTQEPDQRPTFHKIQDQLQL-LRN
FSLNSISQCSDKAKTLGVINEGFEGEDDN-VICLNSD-DVTSVAFMETKNQEGLSYMVVA
TERGRGEQSSEGPLGSKESESCGL-RKEEKEPHADKDICQEQQVASCPSPGKPEGLNYAC
LSHSGDGDGSD-

------------------------------------------------------------
------------------------------------------------------------
-

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGAHAVTLGWKPANVAGVKYVVQWQFSRLPGSWSYTEPVSEPVYTAQPLH
AFTEYTFRV

ENSGT00760000118818_6_Linker_0_1 (190, 233)

VWIVTAQLHLSSPPSTSYRTLA-------TGVPETAPLIRELC

PF00041 // ENSGT00760000118818_6_Domain_1 (233, 305)

SVSPDVVE
VGWSLPLFPGGPVTGYNLRLASDHQTLDAGTQATSFQFSSVLPNTTYR---FSIRAVGQV
DQGPEAEANVTTAPSSTVQEQAQWLFLSRENSLRKRFLEHFVEEAHCLP----TDGRSQR
ITDETGIAVNVQQQLV-----YFCEGNVIWVKDATDMGDASGLHVF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YNGSGTVSSVSVDWLYG----------------
------------------------------------------------------------
-------------------------------KIYFIMSERVWNCDLALCSVPEDITPPSI
VSPKKLVVDPYNGRVLCRPQDSSLQSDFLFFVILYDSTSNADIVFASISLADHFRSDCTS
PLSMVLGTKQAFYRLCIFTFNYSLLGGFFPSAFRPAYLYSTNLYSNKERKSLLTVHVGR-
---V-----GETDNNTTIIICHLSSKLAGETIFGMNWVRINTRDVQSFTLHITGPILNLR
SSRERVFVSFLPPVLPLSRT------------------------VESWGHWQANRSLASQ
SCSLCDGVS-----------VLG-QCGDRSHGNQRSSHSPGVWAVEWKIFFQLIIPSDFA
IWGSDMEEAQDKGRGVGVGARGMWDVGATDYKTWFFTSPQLNPLSEKEWSGNLLKKEKDK
SPPPSPS--KA-RTGEPPQFPS-STPSTLPHFWVSDCVHYYNEMNEIQRRSFRTGRRDTV
VRARFSVNDLAVDSSRGYLYWTTARSVESTRLNGEDSLVLQLQPPFSDKQCLGSTKQK--
---------------------LAHSLTTGSLYSNRPTLLYSTLYRIRIVTE-SFKNIIII
NIIIWSLSAISQPALTYYSGRLFWIDGLGFLTSQEVAQNTAVPVSDPAEFSRLTLVHQSL
RPLPATGNVSSRPEVIPSSVPASSFRIDGNASSFRVLWSAPPPLGWGAIFYCAEIGAHPG
RTGSAGESCTA--PLSEPVLILEGLAPYSPFLLSVTPYSYWGKGPQTTVTLRAPQS-VPS
APENPRIFTVSRRGDKHLRE

PF00041 // ENSGT00760000118818_6_Domain_4 (1521, 1614)

-AGLEFRWDKPRQDNGALENFEIFYQLSGPK---------
---DANEITRGWVVANV---SSPGTTFRLEDVGPEHIIRFQVRAFTCVGPGPFSEVAEFN
TSETHLVPHLVTVHGDQLALLDTDQHQTMWSVQAKEAIGTVGYL----ADKETVFV----
TCGGSLLLLHVHNNVTSEPKKLFEGALVHDTT-ALAVDWISRHLFLAWKTVRNETQIWAI
DLERRVKSLRDLEIRLGSKNSTVVSFSVYPFLSFSRLYWTEASELGHQMFYHDIARGTQH
RILGHPVGTPAPG----RCRVAAPELGGALAIDSSDPLQPLIYFIRGRHEVWATDPEGGR
CQEVARGLAL--PEQAISSVTVDEQFLYWTVEVPDGTVIYQADKRGGTLRSHLATPGWQR
ILASSPALQPLPEKACVDLVPSLKKPTVLSTTNTSLKLLLPPAVARRPC-PGITGPTPTY
LVHYGLVTDNQQPEPRTQYSFFFLTHKLQEFQEPIALLEGLNPFSNYTIRVTVMNYFSDP
HEEPPLGEEIQGTTQQGVPGAVDSVRAAALSDTSIGVSWGAPRLPNGPRASVRYQIAVDR
LPPSPEIPLNRSLLPGGRLTWAIRHLSSGRRYQLK--VLACHPEEPWCTESPVVAAETAR
APERPLLLL

PF00041 // ENSGT00760000118818_6_Domain_7 (2170, 2238)

LGNTSLQLAWKAPA-ANLTAFWFELQKWEY--QERFRANAMCS-PGPEHTC
TITGLRPSTGYG-LRVF

ENSGT00760000118818_6_Linker_7_9 (2238, 2474)

VE-FVGGAKSASPSASFKT-----TGKPAPGTLCGRAEDSRSE
ITNSISSSSGSSNQ----WYLLSQRKDMGESRKGSRSHAAWAVVFNGSCQGICTWKSQHR
SGVFQFRAAAANRLGLGEYSGISEDISLVK--DAFGVPGESV--IIVAVI--SGLLGAVF
LLTFAWHRKGRSRKLPPSNPMVLVQEDKELADLRGRD-NVGLAKACYAIQTLPTRHEIEC
LPAFPRDQLTLKL

PF00069 // ENSGT00760000118818_6_Domain_9 (2474, 2750)

LLGSGAFGEVYEGTALDILGEGSGETKVAVKTLKKGATDQEKMEFLK
EAHLMSKFDHPNILKQLGVCLFNEPQYLILELMEGGDLLTYLRRARVPTF-QAPLLSLVD
LVELCVDISEGCVYLEKMHFIHR-DLAARNCLMSVKDYGSLSRKVKIGDFG--LARDVYK
QDYYRKRGEGLLPIRWMAPESLVDGIFTTRS----------DVWAFGVLVWEILTLGHQP
YPGQSNLEVLHLVQTGGRLEKPRACPSSLWDLLSQCWADDPSQRPSFGHLRDSLRN-LQA
SPLDQPSRGGDTGAPRGVANEAFE------------------------------------
------------------------------------------------------------
------------

MKNIYCLIPKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALKCNDTYATIC--ERESCEVGCSSVERAYEEEVLGNAD
LPTA-PFASSIGSHNMTLRWKSANFSGIKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQIV-----YFSEGTLIWAKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRCAETVRIVESCTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGASSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DPPEVTRIFPNISGTRLNVPELQSATKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-TGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVRESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------RHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNKNE-VVVEFRWNKPKHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVDV---TPSVMSFQLEGMSPRCFIAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIVFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINCTLH
RILQPTVTNQQHKRNQCSCNVTEFELSGAMAIDTSNLEKPLIYFAKA-QEIWAMDLEGCH
CWRVITVPAML-G-KTLASLTVDGDFIYWIITAKDSTQIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-YGITSPTPTY
LVCYAEVNDRKNNSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLK--VLACHFEEMWCTESHPVTVEMFN
APEKPYSLVP

PF00041 // ENSGT00760000118818_6_Domain_7 (2171, 2246)

ENTSLQFNWKAPSNVNLIRFWAELQKWKY--NEFYHVKTSCS-QGPAYVC
NITNLQPHTSYN-VRVVVV-YKTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2471)

NSTSLPESFKT----KAGVPGKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWHRRLKNQKSAKEGLTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLAD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

MKNICWLTLKL-----VKFVVLGCIIWISVAQSTVLSSCLTSCVTNLGRQLDSGTRYN--
-LSEACIHGCQFWNSVDQETCALKCNDTYATIC--ERESCEVGCSNAEGSYEEEVLESTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGVTLRWNPANISGVKYIIQWKYAQLPGSWTFTETVSKLSYTVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APLILNMESWSPDTVE
VSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESTVTT-PSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIHHN
I---TGISVYAQQQVV-----YFSEGTVIWMKGAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YQGSGLVSSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVYVCELKNCSNLEEITPFSL
IAPQKVVVDSYNGYLFYLLRDGIYRVNLPLPS---GRDTKAVRIVESGTLKDFAV----K
PQS----KRIIYFNDTMQLFMSTFLDGSAFHRVLPWVPLV-TVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSVQSYPLPGHPQEVSVL
FGSREALIQWTPPALAIGA------------------------SPSAWQNWTYEVKVYSQ
DILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNGM-DISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDNQCIHLYTAVLRGWS-GGDATIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDPVQESSFRIEGHTSSFQILWNEPPAVDWGIVFYSVEFSTHSK
FLIIE--------QQSLPIFTVEGLEPYTLFNLSVTPYTYWGKGQKTSLSFRAPES-VPS
APENPRIFILSSGRYTKKNE-VVVEFRWNKPKHENGVLTKFEIFYHISKQS---------
---GTNRSTEDWMSASV---IPPVMSFQLEAVSPEYTVAFQVRVFTSKGPGPFSDIVMSK
TSEIKPCPYLISLLGNKIVFLDMDQNQVLWTFSLEGDVSTVGYT----TDDEMGYF----
AQGDTLFLLNLRNHSS---SKLFQDALVSDIR-VIAVDWIARHLYFALKASQNGTQIFNV
DLEHKVKSPREVK--TCKAHTTIISFSIYPLLS--RLYWTEVSDLGHQMFYCNISNHTSQ
HVLQPKASN-QHGRSQCSCNVTESELSGAMTVDTSDPDRPWIYFTKR-QEIWAMDLEGCQ
CWKVIMVPTI-P-GKRIISLTVDGEFIYWIMKTKDDAQIYQAKKGSGAILSQVKASRSKH
ILAYSSALQPFPDKAYLSLASDMVEATILYATNTSLTLKLPPVKTNLTW-HGITHPTSTY
LIYYMEANRA-NSSD---RRHKM-----LESQENVARIEGLQPFSMYMIQIAVKNYYSEP
LEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTESHKPNGPKESVRYQLVMSY
LAPIPETPLRQGEFPSAKLSLLITKLSGGQLYVMK--VLACHPEEMWCTESHPVSVNMFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2247)

TPEKPSALVPENTSLQLDWKARSNVNLTGFWFELQKWKY--NEFYHVKASCS-QGPVYVC
NITDLQPYTSYN-IRVVVV-YTTGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2472)

SSSIPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSRLM----YYTLEV--RKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNL
KGTFQFRAVAANEIGLGEYSEISEDITLV--EDGVWITETSF--ILTIIV--GIFLVATV
PLTFVWHRSLKSHKASKEGLSVLNDNDKELAELRGLAAGVGLANACYAVHTVPTQEEIEN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTF-HGPSLTLLD
LVELCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQL-FRN
VFLNNVSHCGEAAPTGGVINKGFEGEDDE-MVTLNSD-DTMPVALMETKNQEGLNYMVLA
TKCSQGEGSYEGPLGPKELGSCDL-KKDKKQPQADKDFCQEPQVAYGS-PGLSEGLNYAC
LAHSEHGDVSE-

MKNIYWFILNLVNLL------LGC-I-ISGIQCTVLNSCLQSCVTNLGRQLDSGTPCN--
-LSELXXXXXXXXX---------XXXXXXXXXX--XRESCEIGCSSAEGAYEEEVLXXXX
XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAVSKLSYMVAPLH
PFTGYIFRVVWIFTAQLQLYSPPSPSYRTH-P------YGV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPLIRNIESSSPDTVE
VSWTPPQFPGGPILGYNLRLTSKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AEXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXX
X---XXXXXXXXXXXX-----XXXXXXXIW------------------------------
-------------------------------------M-----K------K-----S---
--A------S-----M-----F------D-----M-----S------D-----L-----R
-----I------F-----Y-----R------G-----S-----G-----F------I---
--S-----S------I-----S-----T-----D------W-----L-----Y------Q
-----R-----M------Y-----F-----------------------------------
-----------------------------------IMDELVCVCDLENCSNIEEITPRSI
SAPQKLVADSYNGYIFYLLRDGIYRVDLPVPS---GRDTQAVRIVEGFMLNDFAV----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLILPHVSFT-GVKSFACENNDFLVTNGKA
VXXX-----XXXXXXXXXXXXXXSH----IEEFGFGNLVIFGSSAQPYPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGHPQELSVL
FGSHQALVQWKPPALAIGANV----------FLVSDIIE-LFLGPSAWQNWTYEVKVSTQ
DLSEITHVFSNISGTMMNVPALQSATKYKVSVRASSPKGTGPWSEPSVG--TTLMPX---
------XXXXXXXXXX---XXXXXXXXXXXXXXGEFLSSDIG-VSDMDWYNNSLYYSDTK
GDVYVWLLNGT-HISEDYHIPNIAGAGALAFEWLGHFLYWAGKTYVXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXVESTRLNWESLLVLQAPALFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-AGDTTIT
EFAAWSTSEISQNALVYYSGRLFWINGFRVITAQEIGQRTSVSVSEPAKFTQFTIIQTSL
TPLP--XXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------X-X
---------------------------XXXXXXXXXXXXXXXXXXXXXXXXXASET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRIFILPSGKYH-KNK-VVVEFRWTKPKHENGVLTRFEIFYQISNQS---------
---DTNKTFKDWIAVNV---TPSVMSFQLEDMSPGYTVAFQVRVFTSKGPGPFSDIVKSK
TSEINPFPYLITLLGNKIIFLDMDRHQVVWTFSVERDISAVGYT----IDNEMGYY----
AQGDSLFLLNLHNHSS---SELFRDAVVSNVT-AITIDWISRHLYFALKESQNGIQIFDV
DLEHKVKRPRELK--IFNRNSTIISFYVYPLLS--RLYWTEVSDFGYQMFYYSIINHTLH
RILQPTATNQQTGRSQCFCNVTEFELSGAMTVDTSDLEKPQIYFAKG-QEIWATDLEGCQ
CWRVIMMPGVL-AEQTLVSLTVDGEFIYWIITVKDSTEICQAKKRNGAILSQVKALGSKQ
ILAYSSVMQPFPDKAFLSLASTIGEPTLLNATNSSLTIRLPPATTNLTW-NSITSPTPTY
LVYYTAVNGRKNSSD----RCRM-----LEFQERIALIEDLQPFSTYMIQIAVKNYYSDP
SEHLLLGKEIWGKTKSGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2151)

PEAVWLINTTVQSDTSLTISWRESHKPNGPKELVRYQLAISH
LGLIPETPRRQSEFPNGRLALFVTVLSGGQLYVLK--VLACHSEEMWCAE

ENSGT00760000118818_6_Linker_6_7 (2151, 2162)

SHPVTVKMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2253)

PEKPYALVPENTSLQLEWKAPSNVNLIKFWFELQKWKY--NEFYHAKASCS-QNPAYVC
NISNLQPYTSYN-VRVVVV-YETGENSTSLPE

ENSGT00760000118818_6_Linker_7_9 (2253, 2469)

SFKT----KAGVPSKPGIPKLLEGSKNS
VQWEKAEDNGSRLM----YYLLEI--RKGTSNDSKNQSLKWRMTFNSSCSSICIWKSNNL
KGTFQFRVAAANNLGFGEYSDISENITLVG--DGFWIPETSF--ILTIII--GIFLVVII
PLALVWHRGLKNKKTSKEGLSVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LTLRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNHVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFYSIQDQLQL-FRN
VSLNSISQCRSETNTSGIINEGFEGEDAN-VICSNSD-GVTPIALMEAKNQEGLNYMVLA
TESSQGEESSEGPLGSKESESCGL-RKEEKKQHADKDFCQEKQVAYCP-PGKPEGLNYAC
LTHSGYGDGSD-

MKSPGWLTPKP-----ANAVILGC-IWVSVAQGTVLSSCLTSCVTNLGKQLDIGPPYN--
-LNEACIQGCQFWSSVDQEKCALKCNDAYTTIS--EREACEVGCSTAEGTYEEEVLESID
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGTHSVTLRWDPASISGVKYIIQWKYDRLPGSWTYTETVLKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPSYRT-HP------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIMKIESSSPDTVE
VSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 954)

EAESVITT-PSPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDTILHN
I---TGIAVNVQQQVV-----YFSEGTSIWMKEAANMSDMSDLRSF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISLDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVYACDLENCSNFEEITPLSI
IAPRKVVVDSYNGYVFYLLRDGIYRVNLPLPS---GRHTEAVHIVESSTLKDFAV----K
PQS----KRIIYFNDTMQVFMSTFLDGSAFHQVLPSAPLK-DVKSFACENNDFLITDGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEYGFGNLVIFGSSIQSYPLPGH

PF00041 // ENSGT00760000118818_6_Domain_2 (954, 1064)

PQELSVL
FGSQEALVQWRPPALAIGA------------------------SPSAWQNWTYEVQVSTQ
DLPKATRVFSNISGTTLNVPELQSATQYTVSVRASSPKGPGPWSEPSVG--TTLVP----
--------AAEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLNRM-DVSENYHIPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
AHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESPLVLQAQPWLSGKK----------
------------------VIALTLDLSDGFLYWLVQGNQCIHLYTAVLRGRS-AGDSTIT
EFAAWSPSEISQNALVYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIIQASL
KPLP--GNFSSTPKVIPDSVQESSFRIEGHTSNFQVLWNEPPAVDWGIVFYSVELSAHSK
FLAIE--------QQSLPVFTVEGLEPYALFNFSVTPYTYWGKGQKTSLSLRAPES-APS
APENPRIFVLPSGRYGNKNE-VTVEFRWNKPKRENGVLTKFEIFYHVSKEN---------
---NANKTTEDWTSVIV---KPSVLSFQLEARNLGYIVAFQVRVFTSKGPGPFSDTVMSK
TSEIKPFPYLISLLGNKIVFLDIDQNQVAWTFSTEGDVSTVGYT----ADDEMGYF----
AQGDSLFLLNLHNHSS---SKLFQGALVSDVA-VIAVDWIARHLYFALKASQDGTRIFRV
DLEYKVKSPRELT--ICKRRSAIISFSVYPLLS--RLYWTEVSDLGHRMFYCSISNHTLH
HILQPKASN-PSGRSQCSCNVIESELGGAMTVDTSDPNRPRIFFTKG-QEIWAMDLEGCQ
CWKITMVPAI-L-GKRIVSLTVDGEFVYWIITTKDNTQIYQAEKGSGAVISQVKAPGSKH
ILAYSSVLQPFPDKAYLSLASDVVEATILNASNTSLTLKLPPVKTKLTW-HGITSSTPTY
LVYYTEANRT-NNHS---RKHRM-----LESQENVARIEGLQPFSTYVIQVAVKNYYSDP
LEHLLLGKEIQGKTKSGVPGAVCHINATVLSDTSLHVLWTESPRSNGPKESVRYQLLMSH
LAPIPEKPLRQGDFPNARLALLVTKLSGGQLYVLK--VLACHSEEMWCTESHAVTVNMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2245)

PEKPFALVPDNTSLQLDWKAPSNVNLTRFWFELQKWKY--NEFFHVEASCS-PGPVYVC
NIAGLQPYTPYN-IRVVVV-YMTG

ENSGT00760000118818_6_Linker_7_9 (2245, 2472)

ENSSSSPESFKT----KAGVPSKPGIPTLLEGSKNS
IQWEKAEDNGSRLM----YHILEI--RKGTSSDSQNQSLRWKMVFNGSCSSICTWKSTNL
SGPFQFRAVAANNIGFGEYSGISEDIMLV--EDGFWITETSF--ILTALV--GILLVTTV
PLTFVWYRSLKNHKASKEGLSVLNEDDKELAELRGLAAGVGLANACYAVHTLPTQEEIEN
LPAFPREKLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTI-HGPLLTLVD
LVEVCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RVVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSQS--------DV--WSFGILVWEILTLGHQP
YPAHSNLDVLNYVQEGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQDQLQL-FRN
FSLNITSQCGEEAHASGVINKGFEGEDDKM-VALNSD-DTMPVALMETKNQEGLSYMVLA
TKCSQGEDNSESPLGPKESGSCGL-KQDEKQLDADKDFGQEPQVASCP-PGRSGGLNYAR
LAHTGQGDVSD-

MRNVCLL---L-----NRLGTFYF-IWISAAYCSFSKHCQDLCTSNLEGELGIANLCNVS
DINVACTQGCQFWNATMQVNCPLKCNKTYTKEC--ETVSCKFGCSRAEDAYGVEAQNY

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

LN
KPGA-PFASTIGSHHITLGWKPANISEVKYIIQWKFHQLPGDWRYTEVVSETSYTVKDLQ
AFTEYEFRVVWIITSQLQLHSPS

ENSGT00760000118818_6_Linker_0_1 (204, 219)

SPSYRTHA-------

PF00041 // ENSGT00760000118818_6_Domain_1 (219, 306)

SGVPTTAPIIKDIQSSSPNTVE
VSWSPPLFPNGLIVGYNLILTSENHELLRASRGHSFQFYSTFPNSTYR---FSIVAVNEA
GAGPP

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AEANITTPESKV-KEKAKWLFLSRNQSLRKRYMEQFLEASHCLQ----NGTIQHN
I---TGISVNVYQQVV-----YFSEGNSIWMKGVVDMSDISDLTLF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YTGWGNITSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RIYFVMNEKIHVCQLENCTAAEDVTPLYV
TSPRKIVADPYNGYIFCLLEDGIYRANLPLFP---ETASAASLVVRSHTLRDFMI----N
FQS----KRLIFFNKTEQAFVSGFLDGSEFHTLRSHVPLD-YMESFVYEDNIFTVTDGRA
VFHEEISQVESSSFNEYVVDCSLEY----PEYFGFGNLLFYAASTQPFPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PTLPRLVTVL
FGLDQAVISWSPPEHAIGTS------------------------WSAWQNWTYDVKVSSQ
SPSEEEWVVSNITNTRFTVKDLVNFTEYEMSVRAVSPAGEGPWSEPFRG--KTFEE----
-------EAEEEPYILAVGTEGLWKQRLDSYGQGEFLHPDIRNISDLDWYNDTLYWSNSM
GKVQTWLMNKKEGTIENACVPDIKNARMLAFDWLGQCLYWAGKANTIYRKPLLGGHMDVV
AHVVYVVKDLVVDSVNGYLYWATTYTVESARLNGEEYLILQEHLQFSGKQ----------
------------------VVGLALDLTSGFLYWLVQDSLCLNLYRISICKES-CGNVIVT
EFSGWSISEVSQNALQYYSGRLFWINRLKFITTQEVNQSVSIPFSEPAEFAAFTLVHTSL
KPLP--GNFSFTPKVIPNSVPESSFKIKGNSSSFHIIWSASTDVQWGTVFYCVGSNVLQ-
MRSLESERCLHPHDLTVPSYKVDWLEPFALFDFSVTPYTYWGKAPTTSVYLRAPEG-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APANPRIYVLHNNIHEGEEK-VLVEFRWDKPEMDNGVLTQFRVYYQLLYQS---------
---GAADTLMEWNVSDV---KPTVLLFSIRDVLPRLTVRFQVQAFTSVGPGPMSDVVQRN
SSEFFPVPNLITSSFNKLFLTDIDNNHTIWEVLTNTNIKDICYT----ANDDKVYY----
ILEDSLFLLSVQSTSE---SQFFEDVFLHNVT-AITVDWIARHLFVALKTSWNETQVFFI
DLELKTKSLKALNIQLSKRNSTISSLQSYPFLS--RLYWIEELDHGSRMFYYDILNNTMY
HILGYESVE-EKMRNYCNCNMAEAELGRPMSIDVSDIKEPQLLFIRGRDEIWASDVDGCH
CWRITKIPSFQ--GTKIGSLTVDHQFIYWTVETKEYTEIFLANKESTRHSLQKKANHVLK
ILAYSSAMQSYPDKRCLTPLLDNEKPTILDTTNTSFTLSLPSVTTQQLC-PRISQPTPTY
LVFFREMTNNHENLT---YHFSTIQQKTLEIQEPIAVISNLKPFSSYAIQVAVKNYYSDQ
N-QLALGGETIGTTLCGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2146)

PEEVDSIKAVVLSDTTINISWSEPLEPNGPLESIRYQISVNL
LSLFPEAPLRKSEFPNGMLSWSVSDLQSGTNNLFK--VLAFHPNE

ENSGT00760000118818_6_Linker_6_7 (2146, 2162)

NWFSESVPVTAKTFE
S

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2247)

PLSPSKIIPRNTSFQLEWRAPLHINGTSFWFELSKWETRSDWFSPASTTCT-IGPVYTC
NLTGTLPSANYL-VRATVV-YITGMK

ENSGT00760000118818_6_Linker_7_9 (2247, 2469)

STSFPTSFKTT----AGVPSKPGTPKRAEDSKNS
VQWEKAEDNGSNLT----YYILESREQS---GNTNKVNSLWVVVYNGSCDSICTWKAENL
EGTFQFRVAAANMLGLGEYSDTSKDIVLAK--DTVTSPDI--TAIVAVIGAVVLGLTMII
LFGFVWHQRWKSRKPTLTGQIVLVKEDKELAQLRGMAETVGLANACYAVSTLPSQAEIES
LPAFPRDK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LNLHKLLGSGAFGEVYEGTALDILADGRGESKVAVKTLKRGATDQEKSEFLK
EAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKF-QSPLLTLTD
LLDICLDICKGCVYLEKMRFIHR-DLAARNCLVSEKQYGSCSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLIDGVFTNRS----------DVWAFGVLVWETLTLGQQP
YPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQE-IRH
SPLCFSYFLEDKESVTGFINQAFE--DID-VPPADSD-SILSTTLMEARDQEGLNYLVVV
KESNQDQGSVS-------SAELTS-V----------------------------------
------------

MKNIYCLILKL-----VNFATLGC-LWISVVQCTVLNSCLKSCVTNLGQQLDLGTPHN--
-LSEPCIQGCHFWNSVDQKNCALQCNDTYATIC--ERESCEVGCSSAEGAYEEEVLGNAD
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHDMTLRWKSANFSGVKYIIQWKYAQLLGSWTYTKTVSKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIFTAQLQLYSPPSPSYRTH-P------HGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPDTVE
VSWDPPQFPGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTMYR---FSTAAVNEV
GEGPEAESSITT-SSSAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLR----LDAIYHN
I---TGISVDVHQQTV-----YFSEGTLIWVKKAVNMSDVSDLKIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMEELVCVCDLENCSNIEEITPPSI
SAPRKIVADSYNGYVFYLLRDGIYRADLPVPS---GRRAETVRIVESCTLKDFAI----K
PQS----KRIVYFNDTAQVFMSTFLDGSASHLILPRIPFA-DVKSFACENNDFLVTDGKV
IFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGSSSQLHPLPGRPQELSVL
FGSHQAFVQWKPPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DPPEVTRIFSNISGTMLNVPELQSATKYKVSVRASSPKRPGPWTEPSVG--TTLVP----
--------ASEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDTK
GDVFVWLLNGM-DISENYHLPGIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQSSTGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSK
FLASE--------RHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTALSLRAPET-VPS
APENPRIFILPSGKCCNK

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1611)

NE-VVVEFRWNKPKHENGVLTKFEIFYKISNQS---------
---ITNKTFEDWIAVDV---TPSVMSFQLEGMSPRCFVAFQVRAFTSKGPGSFADVVKST
TSEINPFPHLITLLGNEIAFLDMDQNQVVWTFSAERVISAICYT----ADNELGYY----
AEGDSLFLLNLHNRSS---SELFRDSLVFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPREVK--IHNRNSTIISFSVYPLLS--RLYWTEVSSFGYQMFYYSIINCTLH
RILQPTATNQQNKRNQCSCNVTEFELSGAMAIDTSNLEKSLIYFAKT-QEIWAMDLEGCH
CWRVITVPAMLAG-KTLASLTVDGDFIYWIITAKDSTRIYQAKKGNGAIVSQVKALRSRH
ILAYSSVMQPFPDKAFLSLASDTVEPTILNATNTSLTIRLPLAKTTLTW-YGITSPTPTY
LVCYAEVNDRKNSSD---LKYRI-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWKESHKPNGPQESVRYQLAISH
LAPIPETPLRQSEFPNGRLTLLVTGLSGGNIYVLKK-VLACHSEEMWCTESHPVTVEMFN
TPEKPYSLVPENTSLQFNWKAPLNVNLIRFWAELQKWKY--NEFYHVKTSCN-QGPAYVC
NITNLQPHTSYNNVRVVVV-YKTGENSTSLPESFKTK--AKAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGCRII----YYILEI--RKSTS-NLQNQNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENTILVG-D-DFWIPETSF--ILSIIV--GIFLVITI
PLTFVWLRRLKNQKSAKEGLTVLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGAGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATF-YGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQL-FRN
FFLNSIYQCRDEANTSGVINENFEGEDGD-VICLNSD-DIMPVALMETKNREGLNYMVLA
TECGQGEEKSEGPLGSQESKSCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LSHTGYGDGAD-

MRNINLWKPKL-----LTLLSVYC-LWISTVYCTFLINCQNLCTSGLSQSINIDT---GN
RVSAPCAQGCQFWNTTVQKSCPLQCR-----------VSCKFGCSCAEEAYGAEVQGYLN
T

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHNMTLRWKSANISGVTYIIQWKYNQLPGDWRYTEVISEHSYTVGNLQ
PFTQYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 232)

VWIITSQIQLYSLSSPSYRTHA-------FGVPLTAPIIKDI

PF00041 // ENSGT00760000118818_6_Domain_1 (232, 305)

QSAGPDTVE
VRWSPPLFPRGLIVGYNLLLTSEKQELRTASRGHSFQFYSTFPNTTYR---FTIVAVNEV
GDGPPAEANITTPEPTV-KEKVKWLFLARKQSLRKRSMEFFLEAACYTTEFYSHLGAQQN
F---TGISVNIYQQVV-----YFSEGNSIWVKGAASMSDVSDLKLF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YAGLGKITSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFVINGKVCVCNLENCTVVEDLTSPSI
TSPKKIVADPYNGYVFYLLEDGIYRACLPVYP---GQVPEALPIVRISALKDFVI----N
SQS----KRLIYFNKTDQSFVSSFLDGSEFNILRPQVSFK-DIESFIYENKTFIVTDGRA
VFREELSPAGIKAFNEFMVDCDFTH----VDYFGYNNLLSYGAATQPYPLPAHPQLVTVL
FGSDHAVICWRPPELTIGTILP----------FMQQCDYLHPSGSSAWQNWTYIVKVSDQ
HQAREALVVSNISGTRFTMKELVFSTAFEVSVRAVSPAGEGPWTEPFRG--TTLKE----
--------VEEEPYILAVGDGGLWKQPLDNFGPGVFLSPDIRNASDIDWYNDTLYWSNST
GEVHMWSLSRTTGAIEMSHISDIRKARIVAFDWLGQYLYWAGKANMIYRKSLLVGHVDVV
VHAAFPVKDLVVDAINGYLYWATTCSVESTRLNGENYRMLQEQPRFSGKQ----------
------------------VIALTLDLSDGFLYWLVQDSLCLNLYRVSLCGES-CGDAIVT
EFAGWSSSEVSYSALLYYSGRLFWINGYRFLTIQEINQSINIPFSQPAEFATFTLVQRSL
KPLP--GNFSSPPRVIPELILESSFRIEGNSSHFHILWNASIPVEWGTVFYCVESKVL--
------QRCLPPQSLTVPSYKVEGLEPYILFDFTVTPYTYWGEGPSTSIFLRAPEKTVPS
APANPRIYVSHGAY-EGKHR-A

PF00041 // ENSGT00760000118818_6_Domain_4 (1523, 1614)

SVEFRWNKPKTENGVLTKFRIYYQILNQS---------
---GTNETFTEWNISDV---TPSLMSFSLQDVLPRLTVRFQVQAFTSAGPGPLSNIVEAN
SSDLFPVPTLITISANTLVITDIDRNQTIQSLSAKGGIKVVCYT----ADDETMYY----
IQEDSLFLLNVQNNSR---LQLFRHGFLRNVT-AITIDWIARHLFFSLKTSQKGTQILLM
DLELKAKSLKTLNVQSSNQYLTISSLSTYPFLS--RLYWMETFDSSSRIFYDDIVNNTMH
HILGHEI-----RRSHCSCNVTKTELGRAMTIDMSDSKKSQIFFIKGRDEIWVSDIDGCH
CWKVINVPNLQ--DMTIGSLTVDRLFIYWTVVAKDYTAIYQANKESKILFFQERTQEQVQ
ILAYSTAMQPYPDKGCLTLASHAEKPTILNITNTSFTVCLPPIKTQLHC-TGITLPTPTY
LVYYGKVTNDLRSSA---RCMSGLHCTVMELQENTALIEGLQPFSSYVIQAAVKNYYSDS
SEQPPLGKETIGKTLYGVPEAVNIIETVVLSDNTIKISWNESSQPNGPIDSVRYQIAINF
LPPIPATPLRKNEFPNGTLAWSISSLHGGTCNVFK--VLAFHPEKNWFSESALVLAETFE
TP

PF00041 // ENSGT00760000118818_6_Domain_7 (2163, 2243)

PVPVNITASNTSCELEWRSPLQGNITSFWFELQKWQTKNDWFCPVNITCT-TGPLYKC
HLMGVRPNTNYF-VRVGVV-YI

ENSGT00760000118818_6_Linker_7_9 (2243, 2470)

TGAKSTSTPGSFKTRVCKIAGVPGKPGIPKIAEENKNS
IEWGKAEDNGSSLT----YHILESRKGS---NNTSKMKPSWKVVYNGSCSSVCMWKAKNL
EGTYQFRAAAANMLGLGEYSGISGDIVLIK--ADSTSEGEATIIIAAVTGAIAFILMVTA
LFAFGWHRRWKLRKSAQHGQTVLVREDKELDQLRGLADVVGLSNACYAVSTLPTRAEIDS
LPAFPRDKL

PF07714 // ENSGT00760000118818_6_Domain_9 (2470, 2754)

NLHNLLGSGAFGEVYEGTAVDITGAGSGESKVAVKTLKKGATDYEKSEFLK
EAHLMSKFDHLHILKLLGVCLMNEPQYIILELMEGGDLLSYLRGARGQKF-QGSLLKVAD
LLTICLDICKGCVYLETMHFIHR-DLAARNCLVSVKEYTSLFRIVKIGDFG--LARDVYK
NDYYRKRGEGLLPVRWMAPESLIDGVFTNRS----------DVWAFGVLVWETLTLGHQP
YPGYSNLDVLHHVRSGGRLELPKNCPDDLWDLMTRCWAQEPLHRPTFCCIQDQLQE-LSN
SPMFFTPQLEES-MSSGVLNQAFEDADGD-APSTGSQ-STISATLMESRNVEGLNYLVLA
TESSQDQENRD-------SNELNL-RKEEKAPRADEEISKGKYPALCHTFSDPEGVNYA-
------------

MKNIYWLVLKL-----VNFVTLGC-IWTSVLQCTILNSCLKSCVTNLGRQLDVSTPYN--
-MSAPCIQGCHFWTSADQENCTLKCR-----------ESCEVGCSSGEGAYEEEVLENTD
LSTA-PFASI--SHSVTLRWKSANISG-KYIIQWKYAXXXXXXXXXXAVSKLSYVVEPLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------YGV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPLIKNIESSSPDTVE
ISWAPPQFPGGPILGYNLRLINKNQKLDSGTQRTSFQFYSTLPNTTYR---FSVAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESSIS---SPAVQEEERWLFLSRKTSLRKRSLKHLVDEAHCLQ----PGATHRN
I---TGISVNVHQQVV-----YFSEGTLIWVKGAANMSDVSDLR----------------
------------------------------------------------------------
------------------------------------------------------------
-----I------F-----Y-----S------G----------------------------
------------------------------SGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMAQLVRVCDLENCSNIEEVTPPSI
IAPQKVVADSYNGYLFYLLRDGIYRVDLPVAS---GRGSEVVRIVQSGTLKDFAI----K
PQS----KRIIYFNDTAQVFMSTFLDGSTSHLVLPHVPFT-DVKSFACENNDFLITDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGLYTQPHPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGCPQQLSVL
FGSHQALVQWKPPVLAIGAXXXX----------ISNIV--LFQLGLPWQNW-YEVKVS-T
DFPEATHVFSNISGTIHNVHDLQSATKYKVFVRASSPKGPGPWSEPSVG--TTLVP----
--------AAEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDMGNVSDMDWYNNSLYYSDMK
GDVYVWLLSGT-DISENYHIPNIAGAGALAFEWLGHFLYWAGKTYMIQRQSLSTGHTDIV
THVKSLVNDMMVDSVAGYLY-TTLYSVESTRLNGESSLILQ-QPWISGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-AGDTTIT
EFAAWSTSDISQNTLMYYSGRLFWINGFRIITAQEIDQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDAIPESSFMIEGNASSFQILWNASPAVDWGVIFYSVEFSAHSK
FLASE--------QHSLPVFTVEGLVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRIFILPSDKYHNKNE-VVVEFRWNKPKHENGVLTRFEIFYQISNQS---------
---DTNKTFKDWIAVNV---TSSVMSFQLEGMSLGYSVAFQVRVFTSKGPGPFSDIVKSK
TSEISAFPCLITFFDNKIVLLDMDRNQVVWTLLAEGDVGAMGYT----ADDAVAYY----
AQGDSLLLLNMHNQSS---SEIFRDALVFDIT-IITIDWISRHLYFVLKESQNGMQIFDV
DLENKVKYPRKLK--ICNRNSTIISFSVYPFLS--RLYWTEVSDFGSQMFYYSIINQTLH
RILQPPARNHPNGRSQCSCNVTEFELSGAMTIDTSDLKKPRIYFVKG-QEIWAMDLEGCQ
CWQVIIMPALL-AGKMLVSLTVDGQFLYWISTAKDSTQIYHAKKSNGAILSHMEALSSKH
ILIYSSVLQPFPDRAFLSLASDIAEPTILNTTNTSLTIRLPPVQTNHMW-DGITSPTPTY
LLYYKEVNDRKNSSE---LKDRM-----LXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2146)

PEAVWLINTSVQSDTSLVISWRESHKPNGPKEAVRYQVATSQ
LAPIPETPLRQSDYPNGRLSLLVTRLSGGKLYVLK--VLACHAEE

ENSGT00760000118818_6_Linker_6_7 (2146, 2159)

MWCTESHPVTVET

PF00041 // ENSGT00760000118818_6_Domain_7 (2159, 2253)

FD
TPEKPHALVPGSTSLQLDWKAPSNVHLIRFWFELQKWKH--NEFYHVKVSCS-QGPAYVC
NITGLQPYTFYN-VRVVVV-YRTGENSTSLPE

ENSGT00760000118818_6_Linker_7_9 (2253, 2469)

SFKT----KAGVPSKPGIPKLSEGSKNS
IQWEKAEDNGGRLM----YYILEI--SKGTSKNSQNQNLMWKMAFNGSCSSICTWKPKNL
KGTFQFRVVAVNNLGFGEYSGISEDIIFVG--DGFWISETSF--ILTTII--GIFVVVTI
LLTFVWHRRLKNQKTPKEGLTGLINEDKELADLRGLAAGVGLANACYAIHTLPTQEEIDS
LPAFPREK

PF00069 // ENSGT00760000118818_6_Domain_9 (2469, 2756)

LTLHLLLGSGAFGEVYEGTAVDILGAGSAETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTSF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLAHQS
YPAHSNLDVLSYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHKIQEQLQL-FRN
FSLNSVSQCRGETNPSGVINEAFEDEDGH-RICLNSD-DIMSTALLETKNQEGLNYVVLA
TECRQGEANSEGPLSSKASESCGL-RKEEKESHADKDICQEKQVAYCP-PGKPEGLNYAC
LTHSGCGDGSD-

MRSPCWLTLKP-----VSSVTLGC-IWISVVHSTVLNSCLKSCVTNLGRQLDSGTPYN--
-LSEVCIQGCWFWSSVNQENCALKC-----------RESCEVGCSRAEGAYEEEVLENTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWKPANISGVKYIIQWKYSQLQGSWVYTETVSKLSYMVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 230)

VWIITAQLQLYSPPSPSYRTH-P------YGVPETAPLIR

PF00041 // ENSGT00760000118818_6_Domain_1 (230, 305)

NIESSSPNTVE
VSWAPPHFPGGPILGYNLRLISKNQKSDSGTQRTSFQFCSTLPNTTYR---FSIAAVNEV
GEGPEAESIITT-PSPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDAIHHN
I---TGISVNVHQQVV-----YFSEGTLIWRKEIANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDKLVYVCDLEKCSDFEEITPLSI
IAPQKVVVDSYNGYVFYLLRDGIYRVNLPVPS---ARDTRAVHIVESGTLKDFAI----K
PQS----KRIIYFNDTTQVFMSTFLDGSAPHHVLPWVPFA-DVKSFACENNDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLIIFGSSIQSHPLPGRPQELSVL
FGSHEALVQWKPPVLPIGASE----------CLVPGV----ATGPSAWQNWTYEVKVSTQ
DLSEITQVFSNISGTTLNVPELQSATKYKISVRASSPKGPGPWSDSSVG--TTLVP----
--------AAEPPFIMAVKEDGLWSKPLGSFGPVEFLSSDIGNVSDMDWYNNSLYYSDMK
GNVYVWPLNGM-DISESYHIPSIAGAGALAFEWLGYFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMAVDSVGGYLYWTTQYSVESTRLNGESALILQAQPWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAILRGQSRVGDITIT
EFAAWSTSEISQNALMYYSGRLFWINGFKIITAQEIGQRTSVSVSEPARFNQFTIVQTTL
KPLP--GNFSSAPKVIPDSVQESSFKIEGHASSFQILWNAPPEVDWGIVFYSIEFSAYSK
FLAIE--------QQTLPVFTVEGLEPYALFNLSVTPYTYWGKGHKTSLSFHAPES-VPS
APENPRIFILSRGKYFNKNE-VVMEFRWNKPKHENGVLTKFEIFYCISKQS---------
---STNKTTEDWISVNV---TSSVMAFQLEGMSHGYTVAFQVRVFTSKGPGPFSDIVTSK
TSEINPFPYLLSLLGNKIMLLDMDQNQVVWKFSAEGDVSTMGYI----ANDEMGYF----
TQGDSLFLLNLHNRSS---TRLFQDALISDVA-VITIDWISRHLYFVLKQSQHGTQIFDV
DLELKVKSPRKMK--ICKRNSTIISFFIYPLLS--RLYWTEASNLGHQMFYCSITNNTLH
RVLQPKASN-QHGKSQCSCNVTESELSGAMTVDTSGPERSWIYFTKG-QEIWTMDLEGCQ
CWKVIMMPATLA-GKVIVSLTVDGKFIYWIITTKDSTQIYQAKKRNGAIVSQVKAPRSRH
ILAYSSVLQPFPDKAYLYLASAIVEPTLLNGTNTSLTLRLPPAKTNLTR-HNIFSPTPTY
VVYYTEANGSIQSSD---RKYRM-----LESQENIALIESLQPFSTYMIQVAVKNYYSDP
SEHLPLGKEIWGKTKSGVPGAVCYINATVLSDTSFHIFWRESQKPNGPKESVRYQLLVSH
LAPIPETPLRQSEFPSSRLALLVPRLSGGQLYVLK--VLACHSEEMWCAESHPVIVKMFD
TPEKP-ALVPQNTSLQLDWKAPSNVNLIRFWFELQKWKY--NEFYCIKASCS-QGPAYVC
NITDLQPSTSYN-VRVVVV-YVTGENSSSSPESFRT----RAGVPSKPGIPELLEGSKNS
IQWEKAEDNGSRLM----YYILEI--RKGISNDSQNQGLKWKMAFNGSCGSICTWKSKNL
KGTFQFRVVAANTIGFGEYSGISENVVLL--EDGFWIPET-I--ILTIII--GVFLVVTI
PLTFVWHRRLKSQKASKEGLSVLINDDKELTELRGLPAGVGLANACYAVHSLPTQEEIEN
LPSFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARRTTL-HGPLLTLVD
LVDLCVDISEGCVYLEQMHFIHR-DLAARNCLVSVKDYTNPSRIVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPESLVDGIFTTQS----------DVWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMCQCWAQEPDQRPTFCKIQDQLQLFFRN
ISLSDISQCSYEPNASGAVNEGFEGNDDS-VVALNSN-DVTPVALMETKNREGLNYMVLA
TECSQGDENSEGPLGSKESESCGL-RKDEKQPHADEDFCQE-QVAYCP-PGMPEGLNYAC
LSHSGLGDGSD-

MKGLHRLTPAP-----VNAVILGC-VWISVVQGTVLSSCFTSCVTNLGRQLDTGTPYN--
-LSEACMQGCQFWNSVDQESCALKCAALTHATCLPQRESCEVGCSAAEGAYEEEVLERTE
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHSVTLRWNPANISGVKYIIQWKYDQLPGSWTYTETVSKLSYVVEPLH
PFTEYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLHLYSPPSPKMYTFHPHPVIFLSPVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APFIMKIESSSPDTVE
VSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESLIST-PSPSVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLW----SDTIHQN
I---TGIAVNVQQQVV-----YFSEGPFIWMKEAANMSDTSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGVISSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RLYFIMDKLVYVCDLQNCSNFEEITPLSI
IEPQKVVVDSYNGYVFYLLRDGIYRINLPLPP---GRHAEAVRIVESSTLKDFAV----K
PQS----KRIIYFNDTTQVFMSTFLDGSAFHRVLPWVPLK-EVRSFACESNDFLITNGKA
IFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSIQSYPLPDHPQELSVL
FGSREALVQWKSPALAIGA------------------------SPSAWQNWTYEVKVSTQ
DLPKVTQVFSNISGTMLNVPELQSATKYSVSVRASSPKGPGPWSDPSEG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYYSDTK
GNVYVRPLSGM-EISEKHHIPSIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
AHVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWVSGKK----------
------------------VIALTLDLSDGLLYWLVQGNQCIHLYTAVLRGRS-AGDTAIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSVQESSFRIQGHTSNFQILWNEPPAVDWGIVFYSVEFSAHSK
FLAIE--------QQSLPMFTVEGLEPYALFNLSVTPYTYWGKGQKTTLSLRAPES-VPS
APENPRIFILSSGRHVNKNE-VVVEFRWNRPKHENGVLTKFEIFYHISKQS---------
---GANKTSEDWSSITV---TLPVMSFQLEAMSPGYIVAFQVRVFTSKGPGPFSDTVMSK
TSEIKPFPYLISLAGNKIVLLDMDRNQVVWTFSTERDISTVGYT----ADDEMGYF----
VQGDSLFLLNLHNRSS---SKLFQDALVANVA-AIAVDWIARHLYFALKTSRDGTQIFDV
DLEHKVKSPRELE--ICKSHSAIISFSIYPLLS--RLYWTEVSDLGHQMFYCSISNHTLH
HVPQPKASD-QHGRSQCSCNVMESELGGAMAVDTSDPKRPCIYFTKG-HEIWAMDLEGCQ
CWEVTMEPAV-L-GKRIVSLTVDGEFVYWVITTKDNTQIYQAKKGGGAVVSQVKAPGSKH
LVAYSLALQPFPDKAYLSLASDMVEATILNATNTSLTLKFPPAKTNLTW-HGITSPTPTY
LVYYTEANGT-KNYS---RNHRM-----LESQENVVCIEGLQPFSTYVIQVAVKNYYSDP
LEHLPLGKEIQGKTNSGVPGAVCHINATVLSDTRLHVSWTESHRPNGLRESVRYQLVMSH
LAPMPETPLRQGEFPQARLALLVTKLSGGQLYVLK--VLACHSEEMWCTESHLVTVNTFD

PF00041 // ENSGT00760000118818_6_Domain_7 (2161, 2245)

TPEKPSALVPGNTSLQLDWKAPSNVNLSRFWFELQKWKY--NEFYHVEASCS-QGPVYVC
NIADLQPYTPYN-VRVVVV-YMTG

ENSGT00760000118818_6_Linker_7_9 (2245, 2472)

ENSSSSPESFKT----KAGVPSKPGIPKLLEGSKNS
IQWEKAEDNGSRLM----YYILEI--RKGISNDSQNQSLRWKMAFNGTCSSICTWKSKNL
KGTFQFRTVAVNNIGFGEYSGISEDITLV--EDGFWITETSF--ILTIIV--GIFLVAAV
PLTIVWHRSLKNRKASKEELSVLNEDDKELADLRGLAAGVGLANACYAVHTLPTQEEIES
LPAFPREQLSL

PF07714 // ENSGT00760000118818_6_Domain_9 (2472, 2754)

RLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDREKIEFLK
EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTF-HGPLLTLVD
LVELCVDISKGCVYLEEMRFIHR-DLAARNCLVSVKDYTSP-RIVKIGDFG--LAREIYK
NDYYRKRGEGLLPVRWMAPENLMDGIFTSHIVATLKNQSSPCSFGLNVGKWKQLRLCNMP
FPGLLVMTSW-------HTCFPIFSPMSRWNLMSQCWAQEPDQRPTFHNIHDKLQL-FRN
FSLNHVSQCGEEAHASGVINKGFEGEDNKKMVALNSD-DVMPVALMETKNQEGLSYMVLA
TKCSQGKANPKGPLGPKESGSRGL-KKDEKQPHADKDFCQEPQVADCS-PGGSEGLNYAC
LTHSGHGDVSD-

------------------------------------------------------------
------------------------------------REACEVGCSSAEGAYEEEVLGEDH
I-----------SHSITLRWKSANISEVKYIIQWKYAQLPGSWIYTETVSKLSYIMQALH
PFTEYVFRVVWVFTAQLQLSSPPSPSYRTH-P------RGVPETAPFIRNIESSGPDTVE
VSWTPPQFPGGPILGYNLRLISKYNKFDSGTQRTSFQFYSTLPNTTYS---GAEIIRIC-
---VSVHTVCKL-CCFSVQEEEQWLFLSRKMSLRKRSLKHLVDEAHCLW----SNAIHHN
I---TGEFH---RNI---------------------------------------------
------------------------------------------------------------
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-----------------------------FSRMYFIMNDLVIIK----------------
--VFALLPALYKKYIFFLLRNGIHRVDLPTPS---GRGVKPVHIVESYTLKDFAI----K
PQS----KRIIYFNDTTQVFMSTFLDGSASHPVVPQFPFA-DVQSFACENNDFLVTDGKA
IFQQ-----DSMSFNEFIVGCDLTH----IEEFGFGNLVIFGSSTQPYPVPRCPRDVSVL
FGSHQALVQWKPPALPIGASETMK--------------------------------KS--
------------------------------------------------------------
---------------------------GNNFS---------FFFEDMDWYNNSLYYSDTR
GEVHVWLLNGS-GVSESHRISSIAGAGALTFEWLGRFLYWAGKTYVIHRLSMLTGHSDMV
THVKLLVNDMAVDSVGGFLYWTTLCSVESTRLNGESALVLQAQPWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAGLRGQS-SGAISIT
EFAAWSTSEISQNALMYYSGRLFWINGFSVITAQEIEQRTSVSVSEPARFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSVPESSFRTEGNASAFQVLWSAPPAVDWGVVFYSVEFNAHSK
SLASE--------KQLLPVFTVEGLEPYTLFNLSVTPYTYWGKGPRTSVSLRAPDT-VPS
TPGNPRIFVLPSERSLTKDE-VIVEFRWDKPKHENGVLTRSEIFYHISNHS---------
---DAGRASKGWIAVNV---SSSVTSFQLKAMSPGYTVAFQVRVYASKGPGPLSDIVKSQ
TSGICYLKYVVTLGKQEGA-LEPDICNLLQTYHLLGLRPPASYLTLWLSSSLPGFLILQI
KKINPIFLP--MFSTN---AKLFQDAHISGIT-LLTVNWISRHLYFVRKESQNGTQIFDV
DLEHKVKRPSELK--ICNRNSTIISLSVYPLLS--RLYWTENSNLGCXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXNVTEFDLSGTMTIDTCDLEKPWIYFAKR-QEIWAMDLDGCQ
CWRVIKVPAVHGKTLALVSLTVDKEFIYWIITAKDSSQIYQAKKRGGAAVSRVRAPQSQR
VLTYSCVVQPFPDKAFLFLASNIAEPAILNXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
LVYYAALDDGTNSSY---LEYKILVRLKLESQERTALIEGLQPFSTYIIKMAVKNYYSDS
REHLPLGEAIWGKTKSGVPGAVWFINTTVLSDARLLVSWRGSHQPNGPAELVRYQLAISN
LPLIPKAPLRQSQFPNARFAVLLATLSGGQLYVLK--VLACHPEELWCAESLPVSVKMFD
TPEKPYALAPENTSLRLDWKAPSHGNLSRFWFELQKSNL--EAFS------------Y--
---------------------------------------ICSGVPSKPGVPKLLEGSKNS
IQWEKAEDNGSGLI----YYILEA-RHYFFQSSSVI------------------------
-----PRVLIHK--------------------HLKWINISKE--NKS-----N---ILLS
FSFIVWHKGLKNQKTSEEGLTVLIGEDKELAELRGPVAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_8 (2471, 2551)

LRVLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMRYQSSSEILL---------------

ENSGT00760000118818_6_Linker_8_9 (2551, 2575)

LFWA-----------GGFYIFHGP

PF07714 // ENSGT00760000118818_6_Domain_9 (2575, 2725)

LLTLAD
LVDLCVDVSKGCVYLEQMHFIHRYSYILDTKLLCRVRVLTTGRS-ASGTCGPSLVAEIS-
---------TVLQTRREA----------SEGTPDLPSSSSADLWSFGILVWEILTLGHQP
YPAHSNLDVLNYVQAGGRLEPPRNFVM------L--------------------------
---------ACEVNTTEVINKGFEDDDDS-TIRLNSD-DATPVAFMVTRNQEGLNYMVLA
TELSPSRDNSEGPLCFKDPKSCAL-RKGEKELQADQDLCQEEQVAGCL-PGASPGLNYAC
LTHGGSGE----

MKNIRWLILKL-----VNVATLGS-IWISLVQCTVLNHCLKLCVTNLGRQLDIGTTYN--
-LSEPCIQGCHFWNSVEQENCALKCNDTYAPVC--ERESCEVGCSSAEGAFEEEVLENAN
F

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 190)

PTA-PFASSIGSHGVTLRWKPANISGVKYIIQWKYAQLPGSWTYTEAVSKLSYVVEPLH
PFTEYIFRV

ENSGT00760000118818_6_Linker_0_1 (190, 225)

VWIFTAQLQLYSPPSPSYRTH-P------YGVPET

PF00041 // ENSGT00760000118818_6_Domain_1 (225, 305)

APSIRNIESSSPNTVE
VSWAPPQFPGGPILGYNLRLISKNQQLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGP

ENSGT00760000118818_6_Linker_1_2 (305, 953)

EAESSIST-LSSAVQEEEQWLFLSRKASVRKRSLKHLVDEAHCLQ----SEAIHHN
I---TGISVNGHQQAI-----YFSEGTLIWMKGVANMSDVS-------------------
------------------------------------------------------------
-----------------------------------------------D-----L-----R
-----I------F-----Y-----R------G-----S-----G-----L----------
---------------------------------ISSISVDWLFQ----------------
------------------------------------------------------------
-------------------------------KMYFIMDELVYVCDLGNCSNIEEITPPSI
TAPQKIVADSYNGYVFYLLKDGIYRAALPVPS---GQDSEVLRIVESCTLKDFAV----K
PQS----KRIIYFNDTTRVFMSTFLDGSASHLVLAHVSFA-DVKSFACENYDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVISGSYAQPHPLPG

PF00041 // ENSGT00760000118818_6_Domain_2 (953, 1064)

RPQQLSVL
FGSHQALVQWKPPALAIGT------------------------SPSAWQNWIYEVKVSTQ
DFPEITHVFSNISGTTLHVPKLQSATKYEVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ASEPPFIMAVREDGLWSKPLNSFGPGKFLSSDIGNVSDMDWYNNSLYYSDMK
GDVYVWLLNGT-DISENYHISNIAGAGALAFDWLGQFLYWAGKTYVIQRQSLLTGNTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQSWISGRK----------
------------------VIALTLDLSDGLLYWLVQDSQCIHLYTAVLRGQS-SGETNIT
EFAAWSTSEISQNTLMYYSGRLFWINGFKIITAQEIGQRASVSVLEPAPFNQFTIIQSSL
KPLP--GNFSITPKVIPDSVQESSFRIEGNASSFQILWNAPRAVDWGVIFYSVEFSSLSK
FLASE--------QQLSPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APQNPRIFVLPTGKYHNL

PF00041 // ENSGT00760000118818_6_Domain_4 (1519, 1614)

NE-VVVEFRWNKPKHENGVLTRFEIFYQISNQT---------
---DTNETFEDWIAVNT---TPSKMSFQLEGMSPGYTVAFQVRVFTSKGPGPFSDIVKSK
TAEINPFPYLITLFDSKIVLLDMDQNQIVWTFSTEGDISSMGYT----ADDGMGYY----
VQGDSLYLLNMHNRST---SEIFRGTLVFDIT-IITIDWISRHLYFVQKASQNGMQIFDV
DLEHKVKYPRKLK--ICNRNSTIVSFSVYPLLS--RLYWTEVSDFGSELFYYSIINQTLH
RILPPIATNHSNGRGQCFCGITQFEFSGTMTIDTSDLKKPQIYFVKG-QEIWAVDLEGCR
CWQVVMVPTL--LGRTLESLTVDGEFLYWISSAKDSTQIHQAKKSNGAILSQVKVQRTKH
ILAYSSVLQPFPDKALLHLGSDLAEPTILNTSNTSLTIRLPPARTNLSL-LGITNPTPTY
LVYYKEVNSRKTSSG---LKYKM-----LEFQERIILLDGLRPFSTYVIQTAVKNYYSDP
LEQLPLGKEIWGKTKSGVPEAVRLINTTVQSDTSLTISWRGSQKPNGPQESVRYQLAISH
LALIPETPLRQSEYPNGRLALLVTRLSSGKLYVLK--VLACHAEEMWCSESHPVTVKMFD
TPE

PF00041 // ENSGT00760000118818_6_Domain_7 (2164, 2246)

KPYALVPENTSLQLDWKAPADVNLTRFWFELQKWKD--NEFSRVNASCI-QGPDYVC
NITDLQPYTSYA-VRVVVV-YRTGE

ENSGT00760000118818_6_Linker_7_9 (2246, 2474)

NSTSLPESFKT----KAGVPSKPGIPKVLEGSKDS
IQWEKAEDNGSRLV----YYILEI--RKGISNDSRKQNLMWKMAFNGSCSNICLWKTKNL
KGTFQFRVVAANNLGFGDYSGISENIVLVG--DGFWIPETSI--VLTIII--GIFMVVII
PVVFVWHRKLKSQKTPREGLTGLINEDKELAELRGLAAGVGLANACYAIHTLPTQEEIES
LPAFPRERLTLRL

PF00069 // ENSGT00760000118818_6_Domain_9 (2474, 2751)

LLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTKF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKTGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPTHSNLDVLNYVQTGGRLEPPRNCPDDLWNLLTQCWAQEPDQRPAFHKIQDQLQL-FRN
VSLSSISQCREEADHSGVINEGFEDEDGG-AICLNSG-DVMSIALMETKNQEGLNYMVLA
TGCSQGEENSEGPLGSKESESCGL-RKEEKEPHADKALCQEKQVAYCP-PGKPEGLNYAR
LTHSGYRAGSD-

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----------------------------------SVSAGFCSTSFMWGK-----------
---------------HLPWRAFSSRETKT-VRPLFNWT-----F-------------YME
HVSDDLEY----------L-YL------KHINWYFYFF-SKAGVPSKPGIPKLLEGSTNS
IQWEKAEDNGSRIM----YYILEI--RKGMSDDSQHQNLRWKMTFNGSCSSLCTWKSKNL
KGIFQFRVVAVNNLGFGEYSGISENIILVG--DDFWIPETSF--TLTIIV--GIFLIVTI
SLTFVWHRRLRNQNTPKEGLRILVNEDKELTELCGLAAGVGLANACYATHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARM-TF-HGPLLTMVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLTDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPPFHRIQDQLQL-FRS
FSLNSISQCRDEANTSGVINKDFEGKDGN-MICLNSD-DIMPVALMETKNQEGLNYMVLA
TECSQGEENSKGPLGSQESESCGL-RKEEKEPHADKDFCQEQQVAYCP-PGKSGDLNYAC
LSHSGYGDGSD-

MKIVLWWIWKL-----VYFATLGC-IWISPARCTALNGCVKSYVTNVXXXXXXXXXXX--
-XXXXFIQGCHFWNSVDQENCALKCR-----------EFCEVGCSSAKGAYEEEVLEN

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

AD
LPTA-PFASSIGNHSVTLRWVSTNISGVKYIVQWKYAQLPGSWAYTEAVSKLSYVVESLH
PFTEYVFRVVWIFTAQLQLYSPP

ENSGT00760000118818_6_Linker_0_1 (204, 218)

SPAYRTH-P-----

PF00041 // ENSGT00760000118818_6_Domain_1 (218, 306)

-YGVPETAPVITNIESSSPNTVE
VSWVPPQFPGGPILGYNLRLINKNQKLDSGTQRTSFQFYSTLPNTTYR---FSVAAVNEV
GEGPEAKSTITT-SSPAVQEEEQWLFLSRKISLRKRSLKHLVDEAHCLR----SNAIHHN
I---TGISVNVPQHAV-----YFSEGMLIWVKEAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGRISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMEERICVCDLENCSSIKENPLPTN
NVPQKIVVDSYNGYIFYLLNDGIYRVDLPLPS---AWCATAVRIVESCTLKDFAV----K
PQS----KRIIYFNSTAQVFMSTFLDGSASHLVLPHAPFT-DVKSFACENNDFIVTXXXX
XXXX-----XXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX---------XXXXXXX---X-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXX---
------XXXTEPPFIMAVKEDGLWSKPLNNFGPGEFLSSNIGNVSDMDWYNNSLYYSDMK
GDVYVWLMNGT-DVSENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDVV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPRFSGKK----------
------------------VIALTLDLRDGLLYWLVQDSQCIHLYTAVLRGQXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXVSVSEPAKFNQLLIIQTSL
KPLP--GNFSFTPKVIPDSVQESSFRIKGNASNFQILWAAPPAVDWGIIFYSVEFSAPSK
FLESE--------QQPLPLLTVEGLEPYTLLNISVTPYTYWGKGPKTSVLLRAPEA-XXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX--
---XXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX--XXXXXX
XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXX----
XXXXXXXXXXXXXXXX---XXLFRDAPAHDIK-IITLDWISRHLYFVWKDSQNGIQIFDV
DLEHKVKHPKELK--ICNRNSTIASFSVYPLLS--RLYWTEVSDFGYQMFYCSIINHSLH
RILQPTATN-QDGRSQCTCNVTAYELSASMTLDTSDLKYPKIYFTKE-QEIWATDLEGCQ
CWRVIMVPSMQ-AGKTIVSLTVDGEFLYWIIPEKDSSQIHQARKSSGDILSHTKVPRGTH
ILAYSSAVQPFPDKAFLSLASDLAAPTLLNATNTSITIRLPAAKTKLTL-HGITNPTPTY
LVYYTEVKDETNSSE---LRYRV-----LEFQDRIARIEGLQPFSTYIMRIAMKNYYSDP
MEELPMGKEIWGKTESGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2146)

PEAVFLINATVRSDTSLIISWREAHRPNGPKESVRYQLVISH
LARIPETPLRQSEFPSGRLTLLVPGLSGGQLYVLK--VLACHSEE

ENSGT00760000118818_6_Linker_6_7 (2146, 2162)

MWCTESRPITVKMFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2252)

PEKPYALCPENTSLQLEWKAPSSVKLVRFWFELQKWRD--NGFYHVKTSCT-HSHAYVC
NISDLQPYTSYN-VRVVVV-YTTGENSTSPP

ENSGT00760000118818_6_Linker_7_9 (2252, 2469)

ESFKT----KAGVPSKPGTPKLLEGSENS
IQWEKAEDRGSRLL----YYILEI--RQGISNDSQNQNLSWKMAFNGSCSSICTWKSKNL
KGTFQFRVVAASNLGFGEYSGISEDILLAR--DGFWIPEVNF--VLIIMV--GIFLVVII
PLIFVWQRRLKNQKTSKEGLAIFTNEDKELAELRDLGAGVGLANACYAIHTLPTQEEIKN
LPTFPREK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LTLRVLLGSGAFGEVYEGTALDILGVGSGEIKVAVKTLKKASTHQEKTEFLK
E-HLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LTNVCVDVSKGCVYLEQLHFIHR-DLAARNCLVSVKDYTNPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTESDVXXXXXXXXXXXXXXXX----------X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXWNLMSQCWAQEPDQRPSFHKIHDQLQL-FKL
CCLNSISQHQDERATSGAINESFE------------------------------------
------------------------------------------------------------
------------

MKDIYWLILKL-----VNFVTVGC-IWISVVQCTVLNSCLKSCVINLGRQFDIGTPYN--
-LSEPCIQGCHFWNSVDQENCALKCNDTYATIC--ERESCEVGCSSAEGAYEEEVLEN

PF00041 // ENSGT00760000118818_6_Domain_0 (119, 204)

AD
LPTS-PFASSIGNHSVTLGWKSANISGVKYIIQWKYTQLPGSWTYTEAVSKLTYVVEPLH
PFTEYVFRVVWIFTAQLQLYSPA

ENSGT00760000118818_6_Linker_0_1 (204, 222)

SQSYRTH-P------YGV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PETAPFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLTSKNQNLDSGTQRTSFQFYSTLPSTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESNITT-SSPAVQEEEQWLFLSRKTSLRKRSLKYLVDEAHCLQ----SDIILHN
I---TGISVNVHQQVV-----YFSEGNLIWVKEAANMSDISDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLISSISVDWLYQ----------------
------------------------------------------------------------
-------------------------------RLYFIMDELVCVCGLENCSTIEEITHPSI
VTPQKIVADSYNGYVFYLLRDGIYRVPLPVPS---GQDSEAVRIVESFTLKDFVV----K
PQS----KRIIYFNDTAHAFVSIFLDGSASHLVLPHVSLA-DVKSFACENSDFLVTDGKA
VFQQ-----DSLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSAQLHPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGRPQQLSVL
FGSHQALVQWRPPALAIGA------------------------SPSAWQNWTYEVKISTQ
DFPGTTRFFSNISGTTLNVPELQSATKYKVAVRASSLKGPGPW

ENSGT00760000118818_6_Linker_2_3 (1064, 1397)

SEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMK
GNVYVWLLNGT-DISENYSIPNIAGAGALAFEWLGRYLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLTLQAQTWLSGKK----------
------------------VIALTLDLSDGLLYWLVQDSECIHLYTAVLRGQS-VGDTTIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVLEPAKFNQFTIIQTSL
KPLP--GNFSFTPKVI

PF00041 // ENSGT00760000118818_6_Domain_3 (1397, 1487)

PDSVQESSFRIEGNASSFQILWDAPPAVDWGVIFYSVEFSAHSK
FLASE--------QQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPK

ENSGT00760000118818_6_Linker_3_4 (1487, 1499)

TSLSLRAPET-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRVFVLPSGKHSKKNE-MVVEFRWNKPKHENGVLTRFEIFYQISNQS---------
---DTNKIFKDWIAVNV---TPSMMSFQLEGMKPESIVCFQVRAFTSKGPGPF

ENSGT00760000118818_6_Linker_4_5 (1614, 1940)

SDIVKSK
TSAINPFPYLITLFGNKIHFLDMDQNQVMWTFSSERNISAVSYT----ADNEMGYY----
AQGDSLFFLNVHSLSR---SEIFRDALVFDIT-VITVDWISRHLYFALKESQNGMQIFDV
DLEQKVKYPRALK--NCNRNSTIISFSVYPFLS--RLYWTEVSNFGCQIFYYSIINHTLH
HILQPTATNYQTGRSQCSCNVTEFELSGAMTIDSSDLKQPCIYFVKG-QEIWAMDLEGCQ
CWKVIIVPAVL--GKTLVSLTVDGEFIYWIVTARDSTQIYQAKKRNGAIPSKAKAPRSKH
ILAYSPVMQPFPDEAFLSL

PF00041 // ENSGT00760000118818_6_Domain_5 (1940, 2043)

ASNIEEPTILKVTNTSLTIRLPAAKTNLTS-YGITSPTPTY
LVYCREVNGRKNSSD---QKYRM-----LEFQESIALLEGLQPFSTYIIQIAVKNYYSDS
LERLPLAKEIWGKTKSGVPEAVCLINTTMRSDTSFIISWGESLKPNGPKESVRYQLAISH
LPLIPETPLRQSEFPGGRLSLLVTELSGGKRYVLKKKVLACHPEEMWCAESQPVTVETFD
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2253)

PAKPYALVPENTSLQLDWKAPSNVNLIRFWFELQKWKY--NEFCHVKASCS-QGPAYVC
DITGLQPYTSYN-VRVVVV-YITGENSTSLPE

ENSGT00760000118818_6_Linker_7_9 (2253, 2469)

SFKT----KAGVPSKPGVPKLLEGSKNS
IQWEKAEDNGSRLM----YYILEL--RKSTSNDSQNQNLKWEVAFNGSCNSICTWNSKNL
KGTFQFRVVAANNLGIGEYSGISENIILVG-VDALWLPETSF--ILAITV--GIFLILTI
PLSFVWHTRLKNQKSSKEGLTVLINEDKELAELRGVAAGVGLANACYAIHTLPTQDEIES
LPAFPREK

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LSLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPRYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHEIQDQLQL-FRN
FSLNNISQFRDEANTSGVINEGFEDEDDS-MICLNSD-DITPVALMETKNQEGLNYMVLA
TECSQSEQNSESSLGSKASESCGL-RKEEKEPHADKDNRQEKQVAYCP-SGKPEGLNYAC
LTHSGCGDGSD-

MKDIAWLVLES-----VRVAAIVS-IWMSVLQGTVLNGCLKSCVINLGRQLDSGTPYN--
-LSESCIQGCHFWTSVDQENCPLKCR-----------ESCEIGCSSAEGAYEEEVLENSY
L

PF00041 // ENSGT00760000118818_6_Domain_0 (122, 204)

PTP-PFAASIGNHSVALRWKSANISGVKYIIQWKYTKLPGSWTFTEAVSKLSYVVEPLH
PFTEYVFRVVWIFTAQLQLYSAA

ENSGT00760000118818_6_Linker_0_1 (204, 222)

SPSYRTH--------SHV

PF00041 // ENSGT00760000118818_6_Domain_1 (222, 306)

PESAPFIKNIESSSPDTVE
VSWTPPQFPGGPILGYNLRLTSKNQNFASGTQRTSFQFYSTLPRTTYR---FSIAAVNEV
GEGPE

ENSGT00760000118818_6_Linker_1_2 (306, 951)

AESNITT-SFPAVQEEEQWLFLSRKRSLRKRSLKYVVEEAHCLQ----SDGIHHN
I---TGVSVNVHQQVV-----YFSEGNLIWVKEAANMSDVSDLRIF--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------YRGSGLITSISIDWLYQ----------------
------------------------------------------------------------
-------------------------------RMYFIMDEQVYFCDLENCSAI-EITLPSI
AAPQKLIADSYNGYVFYLLSDGIYRVPLPEPS---GQDSAAVRIVESCGLKDFVV----K
PRS----KRIIYFNDTALAFVSTFLDGSASHLVLPHVPFA-DVKSFACENGDFLVTDGKA
VFQQ-----DALSFNEFIVGCDLNH----IEEFGFGNLAIFASSMQLHPL

PF00041 // ENSGT00760000118818_6_Domain_2 (951, 1064)

PGRPRQLSVL
FGSYKALVQWRPPALAIGANV----------ILVSDIALLFQLGPSAWQNWTYEVKISSQ
DFSETTHFFSNISGTMLNVPELKSATKYQVAVRASSGKGPGPWSEPSVG--TTLMP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDVK
GDVYVWLLNGT-EIAESYLIPNIAGAGALAFEWLGHYLYWAGKTYVIQRQSLLTGHTDMV
TPVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESPLTLQAQTWFSGKK----------
------------------VIALTLDLSDGLLYWLVQDSECIHLYTAVLREQN-MGNTTIT
EFAAWSTSEISQNALMYYSGRLFWIN-FRIITAEG--QR-SVSVXXXXXX-XXXXXXXXX
XXXX--XNFSFTPKVIPDSVPESSFRIEGNALRFQIRWDAPPAVDWGLIFYSVEFSTHSK
FLASE--------QQPLPVFTVEGLAPYALFNLSVTPYTYWGKGPKASVSLRAPEA-V

PF00041 // ENSGT00760000118818_6_Domain_4 (1499, 1614)

PS
APENPRIFVLPSGNYANNNE-VVVEFRWNKPKHENGVLTKFEIFYQIFNRS---------
---MANTTFEDWIAVDV---TPSTMSFQLEGMRPQYIVLFQVRVFTSKGPGPFSDTVKSQ
ISAINPFTYLITLFGNKIHFLDMDLNQVVWTFSSEKDIRAMGYT----ADNKIGYY----
AQRDSLFLLNMNNLSR---VEIFRDALGFDIT-VMTVDWIAKHLYFATKDSQNRTQIFDI
DLEYKXXXXXXXX--XXXXXXXXXXXXXXXXXX--RLYWTEVASLGCQIFYYNIINHTLH
HVLLSSATSHQNGGNHCSCNVTEFEFNGVMAIDNSDLKQPYIYFVKG-QEIWVMDLEGCE
CWSVIPVPAMLA-GQTLVSLTVDGEFIYWIVTTKDSRQIYQAKKSSGATPFQVTAPASQH
VLAYSAAVQPFPDKAFLTLATFIEEPAIVNITNTSLTIRLPAAETNLTW-YGMTSPTPTY
LVCYREASDGKNSSN---QKDRM-----LAFQEHIALIEGLQPFSTYMIQIAVKNYYS--
LEQLPLGKEIWGKTNSGV

PF00041 // ENSGT00760000118818_6_Domain_6 (2059, 2145)

PEAVRLIHTAVRSDTSLIVTWGASHKPNGPRESVRYQLAVSH
LPLIPDTPLRESEFPGGRLTLLVTDLSGGKRYVLK--VLACHPE

ENSGT00760000118818_6_Linker_6_7 (2145, 2162)

EMWCTESHSVTVETFG
T

PF00041 // ENSGT00760000118818_6_Domain_7 (2162, 2247)

PEKPYALLPVNTSLQLHWKAPSNANLTRFWLELQKWKY--SEFYHVKASCS-QGPAYVC
NITDLQPYTSYN-VRVVVV-YITGEN

ENSGT00760000118818_6_Linker_7_9 (2247, 2469)

STSLPQSFKT----KAGIPSKPGISKILEGSENS
IQWEKAEDNGSRLL----YYILEL--RMGAND--RDRNLKWKIVFNGSCSSICTWKSK-L
KGTFQFRVAAANKLGLGEYSGISESIVLA--GDTPWLPETSF--ILAIIV--GIFLIVTI
PLSFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTLPTQDEIEN
LPAFPREQ

PF07714 // ENSGT00760000118818_6_Domain_9 (2469, 2754)

LSLRLLLGSGAFGEVYEGTAVDILGAGSGETKVAVKTLKKGSTDQEKIEFLK
EAHLMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXFCGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRVVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAYSNLDVLNYVQTGGRLEPPRNCPDDLWNLMIQCWAQDPDQRPTFNKIQDQLQL-FRN
FSLKNISQCREQASTRGVINEGFEHEDDT-LMCLNSD-EVLPMALMETKNQEGLNYML-A
TESSQGEPNAEGPLGSQESESCGL-GKEEKEPH---PACQEKQVACCP-SGKPEGLNYAC
LAHSVCGDGSN-

MKNIYWLNLKL-----VNFATLGC-LWISLGQCTVLNNCLKSCVTNLGRQLDTGTPYN--
-LSEPCIQGCHFWNSVHQENCALKCVM-------------------ADGKWK-EELKNAD

PF00041 // ENSGT00760000118818_6_Domain_0 (121, 190)

VPTA-PFASSIGSHSVTLRWKSANISGVKYIVQWKYAQLLGSWTYTETVSKPSYMAEPLH
PFTTYVFRV

ENSGT00760000118818_6_Linker_0_1 (190, 226)

VWIFTAQLQLYSPPSPSYRTH-P------YGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIRNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSVAAVNEV
GEGPEAESSITT-PSPAVQEEEQWLFLSRKTSLRKRSLQHLVDEAHCLQ----SDAVHHN
V---TGQCIREMIPWCEKKDPEFPEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPPSL
IAPQKIVVDSYNGYVFYLLRDGIYRADLPVPS---GREAQAMRIVESCTLKDFAV----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLVLPHVPFA-NVKSFTCENNDFLVTDGKA
VFQQ-----DALSFNEFIVGCDLSH----IEEFGFGNLVIFGLSTQLHPLPGCPQELSVL
FGSHQALVQWKPPALAIGASE----------CAIP---R-VVTGPSAWQNWTYEVKVSTQ
DLPEISHVFSNISGTTLNVPELQSATKYKVSVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDGLWSKPLNSFGPGEFLSSDIGNVSDMDWYNNSLYYSDMK
GDIYVWLLNGT-DISENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESFLILQAQPC---------------
----------------------------------------------------SVGDTIIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITTQEIGQRTSVSVLEAAKFNQFTIIQTSL
KPLP--GNFSFTPKVIPDSVQVSSFRIEGNASSFQVLWDAPPVVDWGAVFYSVEFSAHSK
FLASE--------QQPLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPET-VPS
APENPRIFALPSGKYHKKNE

PF00041 // ENSGT00760000118818_6_Domain_4 (1521, 1614)

-VVVEFRWDKPKHENGVLTRFEIFYQISNQS---------
---DTNKTFEDWIAVNV---TPSVMSFQLEGMSPRCLVAFQVRVFTSKGPGPFSDIVKST
ISEINPFPYLITLLGNKIVFLDMDQNQVVWTFSGEREISAVGYT----ADDEMGYY----
AEGNSLFLLDVHNRSS---SELLRDALAFDIT-VITIDWISRHLYFALKESQNGMQIFDV
DLEHKVKYPRELK--ICNRNSTIISFSVYPLLS--RLYWTEVSDLGYQMSYYSIINHTLH
RILQPTATNHQNGRSQCSCNVTEFELSGAMTIDTSDLEKPLIYFAKA-QEIWAMDLEGCQ
CWRVIMVPAVL-AGKTLVSLTVDGEFIYWIITAKASTQIYQAKKRNGAILSQVKTLRSKH
ILAYSSFMQPFPDKAFLSLASDIEEPTILNATNISLTIKLPLAKTNLTG-YGITSPTPTY
LVYYTEVNEKRNSSD---LKYRM-----LEFQDSIALIEDLQPFSTYMIQIAVKNYYSDP
LEHFPLGKEIWGKTKSGVPEAVWLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAILH
LALIPETPLRQSEFPNERLTLLVTRLSGGNLYVLK--VLACHSEEMWCAESHPVTVETFD
TPEKPYTLVPENTSLQLHWKAPSNVNLIRFWFELQKWKY--SEFYHTEASCS-QGPAYVC
NITDLQPYTSYS-VRVVVV-YVTGENSTSLPESFKT----QAGVPTKPGIPKLLEGSKNS
IQWEKAEDSGNRLM----YYILEI--RYVTSNDSQDLNLRWKMTFNGSCSSICTWKSKNL
KGIFQFRVVAANNLGFGEYSGISENIILVG--DGFGIPETSF--IFTIIV--GIFLIVTI
PLTFVWHRRLKNQKPPKEGPAVLVNEDKEMAELQGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGVGSGELKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTF-HGPLLTLVD
LVDLCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGILIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMIHCWAQEPDQRPTFHRIQDQLQL-FRN
FSLNSVSQCRDEANTSGVINEGFEGEGGN-MICVNSS-DVMSIALMETKNQEGLNYMVLA
TECSQGEKNSEGLPGSQESESCGL-RKEEKEPHADKDFCQEKQVAYCP-PGKPEGLNYAC
LAHSGCGDGSD-

MKNIHWLFLKF-----VNFVTLGC-IWISVVQCTVLNSCLKSCVSSLARQLDIGTPYN--
-LSEPCIQGCHFWNSVEQENCALKCR-----------EFCEVGCSSAEGAYEEEVLGKKM
HLTIISYLY----QLVTCSYQSIVKSF-----------LKYQDFYISAVSKLSFEVESLH
PFTEYIFRVVWIFTAQLQLYSPPSPSYRTH-P------YGVPETA

PF00041 // ENSGT00760000118818_6_Domain_1 (226, 305)

PFIKNIESSSPDTVE
VSWAPPQFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYR---FSIAAVNEV
GEGPEAESSITT-SSLAVQEEEQWLFLSRKTSLRKRSLKHLVDEAHCLW----SDAIHHN
I---TGISVNVHQQVV-----YFSEGALIWVKEAAN------------------------
------------------------------------------------------------
---------------M-----S------D-----V-----S------D-----L-----R
-----I------F-----Y-----R------G-----S-----G-----L------I---
--S-----S------I---------------------SIDWLYQ----------------
------------------------------------------------------------
-------------------------------RIYFIMDGLVCVCDLENCSNFEEITPPSI
IAPQKIVADSYNGYVFYLLRDGLYRVDLPEPP---GRDAKAVHIVASSTLKDFAV----K
PQS----KRIIYFNDTAQVFMSTFLDGSASHLVLPQVPFD-DVKSFACENNDFLVTDGKA
IFQQ-----DTLSFNEFIVGCDLSH----IEEFGFGNLVIFGSSAQPHPLPGRPQEISVL
FGSHQALVQWKPPALAIGELTDNSWFALIVVILVNDIVELFLLGPSAWQNWTYEVKVSSQ
DLHEVTHIFSNISGTMLNVPRLQSATKYKVYVRASSPKGPGPWSEPSVG--TTLVP----
--------ATEPPFIMAVKEDRLWSKPLNNFGPGEFLSSDIGNVSDMDWYNNSLYYSDVK
GDVYVRLLNGT-VISENYHIPNIAGAGALAFEWLGHFLYWAGKTYVIQRQSMLTGHTDIV
THVKLLVNDMVVDSVGGYLYWTTLYSVESTRLNGESSLILQAQPWFSGKK----------
------------------VTILACTSSSSTA------DACTN-----LHCFSRTEDVIIT
EFAAWSTSEISQNALMYYSGRLFWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSL
KPLP--GNFSSTPKVIPDSVQESSFRIEGNASNFQILWEAPPPLDWGIVFYSVEFSAHSK
FLASE--------QLPLPVFTVEGLEPYALFNLSVTPYTYWGKGLKTSLLLRAPET-VPS
APENPRIFILPSGKHLNKNE-VVIEFRWNKPKHENGVLTRFEIFYHISNQS---------
---DLNNTFKQWIAVNV---IPSVMSFRLEGMSPGYIVAFQVRVFTSKGPGPFSDIVKSY
TSEINPFPYLITLLGNKLVLLDMDQNQVVWTFSAEGNISAVGYT----ADNEMGYY----
VQGDSLFLLNLQNRSS---SELFRDALVSDIT-VITIDWISRHLYFV-KESQDGIQIFDM
DLEHKVKYPRELK--NCKRNSTIISFSVSPLLS--RLYWTEVSDLGSQMFYYSIINHTLH
RILQPAATNKQNGRSQCSCNVTEFELSGVMTIDTSKLEKPRIYFAKG-QEIWAMDLEGCQ
CWRIVMVPAIL-AEKTLASLTVGGEFIYWIITTKENTQIYQAKKRTGAILSLVEARRSKC
ILAYSSVMQPFPDKAFLSIASDISGPTILNATNTSLTIRLPPAKTNLTW-YGITSPTPTY
LVYYTEVNGRKKSSD---LVYKI-----LESQESIAVIENLQPFSTYTIHTAIRNYYLDP
LEHLPLGKKILGKTKSGVPEAVWLINTTVLSDTSLLVSWRESHKPNGPEESVRYQLEISN
LALIPKTPLRQSEYPNARLALLVTTLSGGQQYVLK--VLACHSKKMWCAESHSVTVKMFD
TPEKPYALVPENTSLQLDWKAPPDVSLIRFWFELQKWRY--NEFYHVEASCS-KGPAYVC
NITDLQPHTSYD-VRVVVV-YMTGENSTSLPENFKT----KAGVPSKPGVPKLLEGSKDS
IQWEKAEDNGSRLM----YYILEI--RENTSNDSKNQNLRWKMVFNGSCSSLCTWKSKNL
KGTFQFRVVAANSLGFGEYSGISENIILVG--DGFWIPEASF--VLITVV--GVFLVVTI
PLTFVWHRKFKNPKTSKEGLTVLLNEDKELAELRGLAAGVGLANACYAIHTLPTQEEIEN
LPAFPREKLT

PF07714 // ENSGT00760000118818_6_Domain_9 (2471, 2754)

LRLLLGSGAFGEVYEGTAVDILGDGSGEIKVAVKTLKKGSTDQEKIEFLK
EAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMTTL-HGPLLNLVD
LVDVCVDISKGCVYLEQMHFIHR-DLAARNCLVSVKDYTSPSRIVKIGDFG--LARDIYK
NDYYRKRGEGLLPVRWMAPESLMDGIFTTQS----------DVWSFGVLIWEILTLGHQP
YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQESEERPTFQKIQDQLQL-FRN
FSLSSISQCREEANSSGVLNEGFEGEDGN-IISLNSD-DVMPVALMETKNQEGLNYMVLA
TESSQGAENSEGPFCPKESESCSL-RKEEKEPHADKDFCQEKQVAYCP-PGKLEGLNYAC
LAHSGYGDGSD-