Query Results 

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PALQQSPHV
KRVPLTQQ-EPASQQGPGLGKESTTQQEPALRERHVAQPGSGPGEPPPVQQEAESTPEAQ
AKPGAKREPSDPTESTSQETPEQSD-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSMQRSALEWKALSAWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QVSPLHLV
AP------GLAYNMWSALSDSANSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EAIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--SDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPIDR----GLGVNAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IPAR-------------RIRA-----
----------ARGD-----------------GGCGGRH----------------------
----------------------

----------------MEPGSKSVSRSDWQPEPHQRPITPPEPGPEKTPI-AQPESKTLQ
GSNTQQKPASNQRPLT-QQETPAQHDAESQKEPRAQQKSASQEEFLAPQK-PAPQQSPHI
QRVPLTQQ-EAASQQGPGLGKESTTQQEPALRQRHVGQPGPGPGEPPPAQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSNQGSLTELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPAT-MGGMVAQGVKLGFKRKSGYKV
MSGY--GGTSPHEKT------------SARNHRHYQD----TASRLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLIKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSRSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRWDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLENLTLRDLSLRGNSETS--SDTPEMSLSAETLSPSTPSDVNF
LLPPEDAG-EEAEAKN------ELSPMDR----GLGVRAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDNMLKSLPPVHIVACALDPMLDDSV--MLARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPP--AGAGPSGETGA-----
----------AGVD-----------------GGCGGRH----------------------
----------------------

----------------VDPGSKSVSSPDWEPEPHQIPITQPEPGPEKTPT-AQPESTTQQ
GPNTQQEPASQQRPLT-QQESLAQPEAESQQETRAQQKSALQQELLAPQE-PAPQQSPPI
QRVPFTPE-GAASQQGPGTEKESRTQQEPEVEEEHVAQPGSGPVEPPLAQQEAGSTPPSQ
------------TEPMSQEKAGQSDP--NGQQTAP---DKSQRGSLSEWGFL----SKLH
ELSIQRPASEWKTFLEWITDFDSESDPGYPLEMDSPAM-KDGTTAQGMKLDLKEKPGDEE
MSGS--GGTSAQETKT-----------SNQNHRHSWD----TALQLIHN

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSSVFAGVREQALGLEPA-LGRLLGVAHLFDLD
AET--PANGYRSLVHTARCCMAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALT-YYAQRLLATNRPGGLFFEGDEGLTTDFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVAASSLFTGGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTTD
PKLTVTIPPPLAHMGPAPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_6 (695, 728)

SEELNSLVKSEGPRTLELWPRPQQA-
-PRSRYL

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 1150)

VVHIHGGGFVAQTSKSHEPYL-KTWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-IKNCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQPTASPSRLLSLMDPLLPLSVLSKCVS---------AYAGGE---TEEPSNSDQKALGM
MGLVQRDTALLFRDLRLGASSWLNSFLELSGRKSPRDS------------VPIAESMRRS
VSEAALDQPEDPQGTDSLKNLTLHDLSLKSSSET---SGTSELSLSAETLGPSKSSDVNF
LLRREDTS-EEAEAQD------ELSPEDR----GRGIRATFPKGFRPRRSSQGPTQMPIY
SSPIAKNPFMSPLLAPESMLQTLPPVHIVACALDPMLDDSV--MFARRLRSLGKPVTLRV
VEDLPHGFLSLAALCRETRQAAALCVER------IRLVLTPPGTTAPAAPV---------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLTGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQHLLTTNQPGRLFFEGDERVIADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGISVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIQVLSS-LANMASTTVRV-SRLLSLPP---------------VAFEMPLTSD
PELTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKELSSFVKSEGPRSLELRLRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 892)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHP

ENSGT00730000111056_0_Linker_5_7 (892, 1082)

DSDQKALGV
MGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVPK------------TEPMRRS
VSEAALTQPEGPLGTDSLKSLKLHDLGLRNSSDT---TDTPELSLSAEILGSSAPSTVNF
LLGSEDES-EVSEAPE------ELNSK-DR---IRGVGSAFPEGFHPRRCSQGAMWMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

APIVKNPFMSPLLAPDSMLQTLPPVHIVACALDPMLDDSV--MFARRLRGLGQPVTLRV
VEDLPHGFLSLAALCRETRQAAALCVER------IRLILNLPSPPV--------------
------------------------------------------------------------
----------------------

-MKPRRPTSFTREISTVEPDSTSVSR----------PIIQPDPGSETTLT-DHLGSKMLQ
EFGTSQKPS------L-PHEPTAQNEAEFQQKPRVPQKSALLQ-ILSPLASPAPQQSPPS
QKVLLDQQ-EATSHWGPEAGKMSTTPQESQPRKAHVGMTGSGPTEPPLAPHEVEATSTTE
AGPGPPKKSPAQIYSPSQERLEQSDP--TTQQTPEVQETKSKQGSVRESGFL----TRLH
ELSIQRKAQEWKTFFDWITESDTEGHLSSSSQSNLPEP-KSGMVIPGMPLSFKEKPDCEK
VPGY--GRKSPHRMKA-----------SLQPHKHFWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGQLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAEMEAYLAALTQLR
ALS-YYAQRLLAINRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKALNSLVKSEGPR-LELRPRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VIHIHGGGFVAQTSKSHEPYL-KTWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQPSVSPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSDSDQKALGV
MGLVQRDTSLFFRDLRLGASSWLNSFLELSGRKPQKTSAPTAEAVRPQ------ESMRRS
VSEAALAQPESLLNTDSLKTLTITDLSFKGNSET---SDTPEMSLSMETLGPSTPSDVNF
FLRPENSQ-EEAEAKD------DLGTMDR----GPRVRAAFPEGFRPRRSSQGILRMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKTLPPVHMVACALDPMLDDSV--MFARRLRDLGQPVTLNV
VEDLPHGFLSLAALCRETRQAAELCVQR------IRLVLTPPSTPLI-------------
------------------------------------------------------------
----------------------

-MKPGRSISPVRE-ITMEPGSKSVSRSDWQPEPHQRPITPPEPGSEKTPI-AQPESKTLQ
GSNTQQKPASNQRPLT-QQETPAQHDAESQKEPRAQQKSASQEEFLAPQK-PAPQQSPHI
QRVPLTQQ-EAASQQGPGLGKESTTQQEPALRRRHVAQPGPGPGEPPPAQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSRQGSLTELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPAT-MGGMVAQGVKLGFKRKSGYKV
MSGY--GGTSPHEKT------------SARNHRHYQD----TASRFIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PRLTVTISPPLAHTGPGPVLFRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSRSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETS--SDTPEISLSAETLGPSTPSDVNF
LLLPEDAG-EEAEAKN------ELSPMDG----GLGVRAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MLARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPT--AGAGPSGETGA-----
----------AGVD-----------------EGCGGRH----------------------
----------------------

-MKPRRPISFPGEITTMDPSSPSVSRPEWKPETQERPIIKPDPGPETTLT-DHPGSKMLQ
ESGTPQKQS------L-PNEPTAQQEAEFQQEQ-GIQQSALLQKFLTPFAFPAPQQSSPS
QKVHLDQQ-EAISPNGPGAGKVYTTPQEPQLGEEHMGMTKSGPAEPPPA-TEAETTSTVQ
AVSGPDKKPSTQTNLVSQEGPEQSDP--TAQQTPLVQGAKSKQGSLTESGFL----TRLH
DLSIQLTSPEWKSFFDCVTESDIEKCLSSSSKSNPPKP-SYGTAIPEMALLSKKKPEFEK
LSGY--GGKLPHGKKT-----------SLQKHIHYWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGQLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRKSIFFRASHNLAELEAYLAALTQLR
AMA-YYAQRLLTINRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PRLTVTISPPLAHTGPAPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKVLNSLAKSEGPR-LELRPRPHQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 889)

VVHIHGGGFVAQTSKSHEPYL-KNWAQELGVPIFSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQSSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---AE

ENSGT00730000111056_0_Linker_5_7 (889, 1084)

DHFDSDQKALGV
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTTSPTAESVRPT------ESMRRS
VSEAALAQPEGLLGTDTLKKLTIKDLS---NSEP---SDSPEMSQSMETLGPSTPSDVNF
FLRPGNSQ-EEAEAKD------EVRPMDG----VPRVRAAFPEGFHPRRSSQGVLHMPLY
TSP

PF07859 // ENSGT00730000111056_0_Domain_7 (1084, 1149)

IVKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSV--MFARRLRDLGQPVTLKV
VEDLPHGFLSLAALCRETRQATEFCVQR------IRLILTPPAAPLN-------------
------------------------------------------------------------
----------------------

---------------------------------------------------------EEQ
GPRSQQEPISKQGPVS-------WQETSLEQ-----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------EETVTEN-ESVYQQSSASEQ
TP-IAQLGTAPEQIPI-------AHLGPCAP----EQTPV-PXXXXHG-

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRAM-TQSL
V-ALSED-N-A--YFASQGPGDT-ARRLAGAF-GIREQALGLEPA-LGQLLGVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKARYVTTSRKSIFFRAGHNLAELEAYLAALTQLR
ALA-YYAQRLLAVNRPGGLFFEGDGGLSADFLKEYGTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNESGIGVAASSLFTGGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSXXXXXXXXXXXXX------------XXXXXXXXX---XXXXXXXX--
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

ENSGT00730000111056_0_Linker_0_6 (695, 728)

XXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXX

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 1141)

XXHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FFAYCWA-LKNCRLLGSTGERVCLAGDSAGGNLCFTVSLRAAAYGVRIPDGIMAAYPATM
LQASASPSRLMSLMDPLLPLSVLSKCLS---------AYAGVE---PEIQEDQEQQALGV
MGLVKRDTALLLRDLRLGASSWLNTFLELGG------------------------TMRRS
VSEAALQES-SSLPKDSPKSLTLQDLSLVGGS-P---PG---LSSSEETL-SSAPQDVNF
FLPPSGTEDEVLEE-Q-------EESQE----NVDHLGSTFPDGFQPRRSSQGRANLSLQ
TSPIVKNPFMSPLLAHDSMLQSLPPVHIVACALDPMLDDSV--MFARRLRGLGRPVTLRV
V-----------------------------------------------------------
------------------------------------------------------------
----------------------

-----------MTEVTVEPDSKSVSGPDWKPELHKKPITQAEPEPEKTPT-------AQP
EWETQQGPNTQQKPLT-QQEPLAQHEADSQQEPRAQHESASQQESLAPQE-PAPQQSPHI
KRVFTLQ--ETASQKAPGLGKDSTTQQEPELGERRVAQPGLGPGEPPQAQQEAEPTPTAQ
VKPGPQKGPTAQAESTSQETPEQADPVPTAHQTTPVQGAKSKQGSLTDRGFL----TKLQ
ELSIQRSALEWKTLFEWVTDSDSESDVGS-SETDSPAM-ESGTVAQGVRQAFRRKSDNEV
MPEY--SGTSPHRKKT-----------STKNHRHYKN----TASRLIHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-AQRLSSVFAGVREQALGLEPA-LVCLLSVAHLFDLD
AET--PANGFRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALT-YYAQRLLATNQPGRLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERVIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVKV-SRLLSLPP---------------KAFEMPLIAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKAEGQRSLELWPRPHQV-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VIHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIVSIDYSLAPEAPFPRALEEC
FFAYCWA-IKNCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGIRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHSNSDQKALGM
MGLVRRDTALLLRDLRLGASSWLNSFLELSGRKSQKTSEPM------------AEPMRRS
VSEAALAQPEGPLGTDSLKNLTLKDLSLRGSSETSGT---PEMSLSAETLGPSTHSDVNF
LLRPEDAP-EEAVAGN------ELSTKDR----GPGVQATFPTGFHPRRSSQAATQMPLY
SSPIVKNPFMSPLLAPDSMLKGLPPVHIVQCSCMPPRLCSYQNTFFSSLAP---PAP---
----------------------------------------PRSSSNPPPNPFLTKTTPKI
AYPGLLPPLHTPPINVCPLL----------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHI
KRVPLTQQ-EPASQQGPGLGKESTTQQEPALRERHVAQPGSGPGEPPPVQQEAESTPKAQ
AKPGAKREPSDPTESTSQETPEQSD-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 535)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QV

ENSGT00730000111056_0_Linker_0_3 (535, 563)

SPLPRL
SA---------------LSDSA

PF06350 // ENSGT00730000111056_0_Domain_3 (563, 694)

NSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_3_5 (694, 728)

DSEELSILVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--SDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPIDR----GLGVNAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLILTPPAAPTPA-PPLV-------
------------------------------------------------------------
----------------------

MINPGRSTSPLREVKREEPGSKSVSRPDWEPEPHQELTTQPDP-----------ESKTQQ
GSNTQQKPVSQQRPLT-PQELLPQHEAESQQELRAQQKCASQQEFLAPQE-AVPHQSPPI
KSPHFTQQ-EATSQQGPGPGKESTTKQESELRERHVVQPEPGRVEPPLTQQETESALTAQ
ANPGPKMGTPAQIESTGQERPEQSNP--TAQKTTPIRGA--RQGCLTERGFL----TKLQ
ELSTQRSSLDWKTFFDWVTDTDSESNMWSSS------K-KDGTVAQGVKLAFRKKSRYEG
TSGY--CGTLPHVKKT-----------SAQNHRHYQD----TASRLIHN

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLHTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFAGVREQALGLEPV-LGRLLGVAHHFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALT-YYAQRLLATNRPGRLFFEGEEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGS-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SEELSTLLKCEGQRNLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCELLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---IED

ENSGT00730000111056_0_Linker_5_7 (890, 1084)

HSDPDQKALGV
MGLVRRDTALFLRDLRLGASSWLNSFLELSGRKSQKTSEPMAGWVQPTDPALLTEPMRRS
VSEAALAQPEGPMGTDSLKT--LKDFSLRSSSDT---SDTPEMSLSAETLGPSKPSDINF
LVGPADAS-EEAEARN------EVGTRDS----GQGVHAAFPEGFHPRRTSQGATQMPLF
SSP

PF07859 // ENSGT00730000111056_0_Domain_7 (1084, 1149)

IVKNPFMSPLLAPDSMLKTLPPVHIVACALDPMLDDSV--MFARRLRGLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLIITPPASPPV-------------
------------------------------------------------------------
----------------------

----------------VEPDSKSLSRPDWEPKPHQTPITQPEPEPKVTATAQAV-SKTHQ
GPNTQQEPTLQQRPLT-QQEPLAQHDAESQQEPSTHQNSALQKELLAPQE-PAPQQSPPI
HQVPFSQQ-EVASQQAPGSGKEPETQWEPELREAKVAQPGPGPEQKPPAKQKDGTTPPIQ
PRP--KIRSPAQIESISQERMGHS--DPKAQQTDPAQGAKSQQRSLIKWGFL----SKLH
QLSTQGPASEWRTLFEWVTDSDSESDLRSPLKSNFPAK-RSGTVAQGMKLASKGKHE--V
ALGH--GGTTAH------GKKTG-----SQSQRHYRD----TASRLTQN

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLVALTQLR
ALA-YYAQRLLATNRPGGLFFEGDEGLIAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PKLTVTISPPLAHSGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SEELSSLVKSEGPRSLELRPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPIVSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLTKCVS---------AYAGGE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

RSDSDQKALGM
MGLVRRDTALLFRDLRLGASSWLHSFLDLSGHKSHTNSVPT------------AEPMRRS
VSEAALAQPEGLLGTDSLKSLTLHDLSLKGSSDT---SETPELSLSAETLGSSTPSNVNF
LVGPEEAP-EEAAKTQ------ELSAKDR----GCGARAAFPEGFHPRRSSQGCTWMPVC
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLASDSMLQSLPPVHIVACALDPMLDDSV--MFARRLRGLGKPVTLRV
VEDLPHGFLSLAALCRETRHAAALCVER------IRLVLTQPA-----------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MDLHTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLTSVFAGVREQALGLEPA-LVRLLGVAHLFDLD
SET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLVALTQLR
ALA-YYAQHLLATNQPGGLFFEGDERLTAEFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASVTVRI-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLIRL-ISYELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEAISNLVKSEGPWSLELRPRHQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHSGSDEKALGM
MGIVRRDTSLLLRDIRLGASSWLNSFLELSGHKSQKKPVPV------------AEPIRRS
VSEAALAQQESPLDTDSLKGL--KNLSLKGYSESSDTSKLSEMSQSLEALAPSKPSEVNL
FLRPEDAL-EEAEANE------ALSTKDR----GPGSPATFPEGFHPRRSSQGPIHMPLY
SAPIVKNPFMSPFLFTGKKLRYVRSK----C-SEPLFTDKR--SVRHS------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------TSPERTEE-----SDNQATPTQEPKSQQGSLAQLGFL----SKLQ
GIAMPPPPPEWKAFIDWVTDSDSESDLDTSLGTNWSAL-RIGT-------SFGEASGYEM
KSGY--DEPSAHRKNS-----------STQNLRHYRD----TTWLVIRS

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 696)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFSGIREQALGLEPA-LASLLGVAHNFDLD
PET--PANGYRSLVHTARCCLAHLLHKARYVASNRRSIFFRTSHNLAELEAYLVALTQLR
ALDTDYAQHLLTTNRPGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXX-XXXX---X---------------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLIDPLLPLSVLSKCVS---------AYAGGE---TDDQSNSEEKALGM
MGLVRRDTALLFRDLRLGASSWLNSFLELSGQKPHKTP--------------KTESMRRS
VSEAALAQPEGPLGTDSLKNLNLHDLSLRGSSES---SDNPELSMSAEALGPSKPSDINF
LLGPEDSRQEMNE---------MSSLKD----SPQGMNAAFPKGFYPKISNLASMQIPIY
S-PIVK

PF07859 // ENSGT00730000111056_0_Domain_7 (1087, 1150)

NPFMSPLLAPDSMLQTLPPVHIVACALDPMLDDSV--MFARRLRGLDRPVTLRV
VEDLPHGFLSLASLCRETRQAAALCVER------IRAVLAPPG-----------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
MGLVKRDTAQLFRDLQLGASAWLQTFLELGGRAGKQGAPAT------------ADSMRRS
VSEAALREPHASASRESHKSLTCQDLSSIGSADPGAGG-----------PPAPPRQDVSF
FLNQPPEPPAAPAAEE------PLEP------EAPGPGLTFPPGFEPRRSDQGEAR

PF07859 // ENSGT00730000111056_0_Domain_7 (1077, 1149)

LALQ
TSPIVKNPFMSPLLAPDSMLRGLPPVHIVACALDPLLDDSV--MFARRLRAVGRPVTLQV
VEDLPHGFLSLAALCRETRQAAALCVDR------IRHILVPSPTSRSSTASWSA------
AAPTPVPPRAPG-PRLCPNRPPPS----PTLHPVEPPVPPRPWGGGAAKH----------
----------------------

----------------MEPGSQSVSRPDWEPEPHLRPITLPEPRPEETPT-AQPESKTPK
GSNTQQEPASKQRPLT-QQEPPAQHDAKSQNEPRAQHISALQEEFLAPQK-PAPQQSPHI
KRVPLTQQ-ETASQQGPGLEKESTTQQEPALRQRQVAQPGPGPGKPTPTQQEAESIPAAQ
TKPGAQRKPPAPTESISQETSEQSDP--TTQRTTPVQGAKSKQGSLTEPGFL----KKLQ
ELSIQQSALEWKAYFEWVTDSESESDMGSSSDIDSSAM-TAGMVAPGVKLALKRKSGYKA
MSGY--GGTSPHEKT------------SARNHRHYQD----TASKLLHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-ARRLSSVFEGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLIRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYTGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

HSNSDQKALGM
MGLVRRDTAMLLRDFRLGASSWLNSFLELSGRKSQKIS------------EPTAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSET---PDTPEISLSAETLGPSMPSNVDF
LLPPEDAG-EEAEAKN------ELSPMDK----GLGVSATFPQGFHPRRSSQGPTQMPLY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLDRPVTLHV
VEDLPHGFLTLASLCRETRQAAELCVER------IRLVLTPPAAPTPASREDEGC-----
----------RGK--------------------H--------------------------
----------------------

----------------VEPGSNTVSRPDWESEPHKRPTTQSEP-----------ESKMQQ
GSNTQQKPASQPRPLT-QQELLTQSKAESQQEPRTQQKSVSQQEFLAPQG-PVPQQSPPI
RRVCFTQQ-EAVSQQGTGSGKGSTTKPEPELREGHIAQPGPGPVEPPLAQQETESTPTAQ
AKPGPKKGTPAQIESTCQERLEQSDP--TVQQTTPTQGAKSRQEYSTEQGFL----TKLQ
ELSTQPSALEWKAFFEWVTDFNSESDVQSSSETDPLAT-RDGTVAQGVKLAFKKKPSYEV
ISRY--GGTSPHGRKS-----------SAQNHRPYQD----TASRLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFASQGPGET-ARRLSGVFAGVREQALGLEPA-LGSLLGVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKARYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQSLLATNRPGRLFFEGDEGLTAEFLQEYVTLHKGCFYGRCLGF--QFTPSIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERVIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTTD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSEGQWTRELWQRAQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 887)

VVHFHGGGFVAQTSKSHEPYL-KGWAQELGAPILSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICVAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYSGAE---

ENSGT00730000111056_0_Linker_5_7 (887, 1085)

TEDNSDSDQQALGV
MTLVRRDTAVLFRDLRLGASSWLNSFLELSGRKTQKMA------------QPVAEPMRRS
VSEAALAQPEGPLGTDSLKNLTLKDLSMRSSSDT---SDTAEMSLSAETLGPSKPSNVNF
LVGSENAR-GPVEARS------ELSPKDR----GLGAQAAFPEGFHPRRSSQGPTQMPLY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFVSPLLAPDSMLKTLPPVHIVACALDPMLDDSV--MFARRLRSLGQPVTLRV
VEDLPHGFLTLASLCRETRQATELCVEH------IRLILTPPAARRAG------------
-------------D-----------------GGCGGRH----------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHI
KRVPLTQQ-EPASQQGPGLGKESTTQQEPALRERHVAQPGSGPGEPPPVQQEAESTPEAQ
AKPGAKREPSDPTESTSQETPEQSD-----QQTTPVQGAKSKQRSLIELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYNMDLHTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEMEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1074)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSHKIS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--SDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPMDR----GLGVNAAFPEGFHPRRSSQG

PF07859 // ENSGT00730000111056_0_Domain_7 (1074, 1149)

ATQMPLY
SSPVVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPPAAPAPA-P--PLV-----
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHI
KRVPLTQQ-EPASQQGPGLGKESTTQQEPALRERHVAQPGSGPGEPPPVQQEAESTPEAQ
AKPGAKREPSDPTESTSQETPEQSD-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYNMDLHTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEMEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TEDHSNSDQKALGM
IGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--SDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPMDR----GLGVNAAFPEGFHPRRSSQGATQMPLY
SSPVVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDARM--VPARRMRTCQRCARTPV
VERIARPNR-------------------------LRAAGRRPT--SVE-PARRES-----
----------AARG-----------------TGCRGEL----------------------
----------------------

----------------MEPGSKSVPRPDWQPEPHQRPIIPPEPGPEKTPT-AQPESKTLQ
GSNTQRKPASNQRPLT-QQETPVQHDAESQKEPRAQQKSASQEEFLAPQK-TAPQQSPHI
QRVPLTQQ-EAASQQGPGLGKESTTQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQ
AKPAAKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSKQGSLTELRFL----TKLQ
ELSIQRSALEWKALAEWVTDSESESDVGSSSDTDSPAT-MGGMVAQGVKLGFKRKSGYKV
MSGY--GGTSPHEKT------------SARNHRHYQD----TASRLIHN

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHIARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 698)

SEE

PF10340 // ENSGT00730000111056_0_Domain_5 (698, 820)

LSSLVKSNGQRSLELWPRPQQA-
-PRSRSLIVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVAL

ENSGT00730000111056_0_Linker_5_7 (820, 1084)

RAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TEDHSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGADSLKNLTLRDFSLRGNSETS--SDTPEMSLSAETLGPSTPSDVNF
LLPPEDAG-EEAEAKN------ELSPMDR----GLGVRAAFPEGFHPRRSSQGATQMPLY
SSP

PF07859 // ENSGT00730000111056_0_Domain_7 (1084, 1149)

IVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MLARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPP--AGDGG-----------
---------------------------------CGGRRGPRG------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M-ESAG-GSGPAGARVSKNK---
---------KEGLKSR-----------TRRRWRWLKL----KASRLMHTMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQTL
V-TLAED---NMAFFSSQGPGET-ARRLTSVFAGVREQALGLEPA-LIHLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLVALIQLR
ALT-YYAQHLLATNRPGGLFFEGDEGLTAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNVTEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLIRL-ISHELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSEGPWNLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 888)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-LKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATT
LQSAASPSRLLSLIDPLLPLSVLSKCVS---------AYAGAE---TEDQSTSDQKALGM
MGLVRRDTSLLLRDLRLGASSWLNSFLELSGHKSQKTQVPVPPL-------T-HPPIRRS
VSDAALAQPESPLGTDSLKAL--KDLN---------THKMSEMSQSLETLGPSTPSDVNF
FLRPEDAQ-EEAEAKE------GLSTKDR----ALGSRATFPEGFHPRRSSQGATHMPLY
SAPIVKNPFMSPLLAPDHMLRTLPPVHIVVRAAREDAHTGG-------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M-ESAG-GSGPTGALASKNE---
---------KEELKSR-----------SRRRWRKAKA----KASRLMHTMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLTSVFAGVREQALGLEPA-LVRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAAITQLR
ALA-YYAQHLLATNRPGVLFFEGDEGLTAEFLSEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERVIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVKV-SRLLSLPP---------------EAFEMPLTSD
PRLTVTISPPLAHTGPGPVLIRL-ISYELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEALSSLVKSEGPWNLDLRPWPQHA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 883)

VVHFHGGGFVAQTSKSHEPYL-KGWAQELGVPIISIDYSLAPEAPFPRALEEC
FYAYCWA-VKNCALLGSTGEQICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQTAASPSRLLSLMDPLLPLSVLSKCVT---------AYAGA

ENSGT00730000111056_0_Linker_5_7 (883, 1085)

E---TEDYSSSDQKALGM
MGIMRRDTSLLLRDLRVGASSWLNSFLELSGHKSQKKPVPVTDPD------PPTESIRRS
VSEAALAQLDSPVGTDSLK----------GCSESSDVAKMPEVSQSLETLGPSQASDVNF
FLLPEDAL-EEAEAKE------GVSTRDT----GPSNRAAFPEGFQPRRSSQGPTHMPLY
SAPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDHMLKTLPPVHIVACALDPMLDDSV--MFARRLRALGQPVTLRV
VEDLPHGFLSLASLCRETRQAAQLCVER------IRLVLT-------PPAAPQP------
------------------------------------------------------------
----------------------

----------------VEPGAETVSRLDQEPEPHQTPITQPEPGPEEAPTAQP-ASKTQQ
GPNTQQEPASQQMPFT-QQESLAEHEAESQQEPRTQQKNALLQEFLAPQE-PAAQQSPPT
QRVRFAQQ-EAALQRRPGPGLESRSQKEPHLREGCAAQTGSGPGEPPLAQREAGSTPPDQ
PRHGPQNGPPAQIESMSQETPGQSVP--TAQPTAPVQGAKSQQGSFMEWGFL----SEWN
QMSSQQPASGWKTRFEWVTDLDSESDSGSQSGSDSPST-RGGTVAQEMKLVFKGKSGYGV
MSGY--GGTSAPGKNS-----------PSKKHRHYRH----TGQSFIQSGVLRAT-STSV
S-PGARD---AVDFCSAFGAGAQKALRRGGDTAALREQSSGLPEMATPSLLTVGSVRDRE
KEQ--HSDIHRNTAETSSAILAGSVTPSSLHEGLGSSLFPTTLHKLLVLSKVIRA-TEKN
GAV-YIPERPMRSTKANRLARQG

PF06350 // ENSGT00730000111056_0_Domain_0 (504, 620)

VHGLTEGNISHYLTLYGMSLFAYCLGISPQFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSGKTS-LQAAPFPA-PLLGSEPS---------------SGSSLSLSPQ
PPLPSPTTQPSATCLPPPLPLSS-ISASALS-PTAPLLTQLSISTTSSCASCSPTPALML
HPLHLSISSDLGRATPVALLCCQPEPWPSISWPWMPLPPEMALSLSFPP-TLLASDLQPC
KLPQSFLISGPLHVLSS

PF07859 // ENSGT00730000111056_0_Domain_5 (798, 891)

TGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLSKCVS---------AYAGGE---TEDH

ENSGT00730000111056_0_Linker_5_7 (891, 1068)

SDSDQKALGM
MGLVRRDTALLLRDLRLNASSWLNSFLELSKHKAHTNLVPV------------VEPMRRS
VSEAALAQPEGPLGTDSLKSLTLHDLSLKGSSET---SENPELSLSAETLASSTPSDVNF
LLQSEGTV-EAAKAQE------EMSTKDR----SRGVGAAFPEGFHP

PF07859 // ENSGT00730000111056_0_Domain_7 (1068, 1149)

RRSSQGATRMPLY
SSPIAKNPFMSPLLAPDSMLQSLPPVHIVACALDPMLDDSV--MFARRLRSLGQPVTLRV
VEDLPHGFLSLAALCRETRQAAALCVER------IRLILAPP------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPA-LGSLLSVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQRLLATNRPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPSIRP
FLQTISIGLVSFGEHYKRNESGLGVTASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLISLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLIRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELNSMVKSEGPRILELRPRPQQT-
-SRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 891)

VVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEEH

ENSGT00730000111056_0_Linker_5_7 (891, 1067)

PNSDEKALGM
MGLVRRDTSLLLRDLRLGASSWLNSFLEFSGQKSQKTS------------APTVESMRRS
VSEAALAQPEGPVGTDSLKILTLKDLNLKSSSET---SETPEMSLSVETLGPSTPSDVNF
FLRPEDAR-EEAEAKE------GLSANDG----SSRVSNAFPEGFH

PF07859 // ENSGT00730000111056_0_Domain_7 (1067, 1149)

PRRTSQGATQMPLY
SSPIVKNPFMSPLLAPDNMLKTLPPVHIVACALDPMLDDSV--MFARRLRALGQPVTLRV
VEDLPHGFLSLASLCRETRQAAELCVER------IRLILTPPAAAAAAAPPPL-------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M-ESTG-ESGPAGARASKNE---
---------KEGLKSR-----------SRRRWRKAKA----KASRLMHTMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQTL
V-TLAED---NMAFFSSQGPGET-ARRLTSVFAGVREQALGLEPA-LVRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRHSIFFRTSHNLAELEAYLVALTQLR
ALT-YYAQHLLATNRPGGLFFEGDEGLTAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLVRL-ISYELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSEGPWSLELRPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KTWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1083)

HSNSDQKALGM
MGLVRRDTSLLLRDLRLGASSWLNSFLELRGHKSQKTQVPVAAA-------SPTETMRRS
VSDAALAQPESPLGTDSLKAL--TDLSLKSSSESSDTPKMSEMSQSLETLGPSTPSDVNF
FLRSEDAQ-EEAGAKE------GASTKDR----GLGSRATFPEGFHPRRSSQGVIHMPLY
SV

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDHMLKTLPPVHIVACALDPMLDDSV--MFARRLREVGQPVTLHV
VEDLPHGFLSLASLCRETQQAAQLCVER------IRLILT-------PPAAPLS------
------------------------------------------------------------
----------------------

-MKPGKSTPPMREITTVEPGSKSVPRTDGRPAQEQTPTTQPEPKPEKIPKIAKPRTKTQQ
ESTAQQEPASQQRPST-QQEPQAQHEAEHQQEPRTQQKSTLQQALLASQE-SVPQQSSPI
KRLPLTQQ-EAPSQQGPSPRKESTTQQKSVLREGQAARPGLGPVEPPLAQQEAESKPRAQ
AKLASKIGPPAQIQSTSQERAQQSDA--MAQQTTPVQRAKSRHESLTEDRNLQETSTTPQ
EISTEPSPQEWRTLLEWITDSDSESDVGSSSETDAVAM-RGVTAINRAKTAFKEKSGHEG
MSGH--GGPSFGKK---------------TSTRHYRD----TPSRLVHS

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSSVFAGVREQALGLEPA-LGRLLGVAHLFDLD
AET--PANGFRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQRLLATNRPGGLFFEGDERLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMTSANVRV-SRLISLPP---------------EAFNMPLTSD
PKLTVTISPPLAHTGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SEELNILAKSEGPRSLELRPRGQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 891)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPARAGGV
LLRPTAGPSSTAPSLAQQESGFALRGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATL
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAQ---TEDH

ENSGT00730000111056_0_Linker_5_7 (891, 1086)

SNSDQKALGM
MGLMRRDTALLLKDLRLGASSWLNSFLELSGRKAKSS-------------APMSEPMRRS
VSEAALAQPEGPLGTDSLKSLTLKDLSVKGSSEA---TDTPEMSLSAETLGPSSASDVNF
FLRPEDSV-EEAEARE------ERGAKDR----GQGVRAAFPEGFHPRISSQGATHMPLF
SSPIV

PF07859 // ENSGT00730000111056_0_Domain_7 (1086, 1149)

KNPFMSPLLAPDNMLKTLPPVHIVACALDPMLDDSV--MFARRLRCLGQPVTLRV
VEDLPHGFLSLAALCRETREATELCVER------IRLVLTHPAPAAQPPLL---------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M-ESTG-ESGPAGARASKNE---
---------KEGLKSR-----------SRRRWRKAKA----KASRLMHTMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQTL
V-TLAED---NMAFFSSQGPGET-ARRLTSVFAGVREQALGLEPA-LVRLLGVAHLFDLD
PET--PANG---LVHTARCCLAHLLHKSRYVASNRHSIFFRTSHNLAELEAYLVALTQLR
ALT-YYAQHLLATNRPGGLFFEGDEGLTAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLVRL-ISYELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSEGPWSLELRPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KTWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1083)

HSNSDQKALGM
MGLVRRDTSLLLRDLRLGASSWLNSFLELRGHKSQKTQVPVA------------ETMRRS
VSDAALAQPESPLGTDSLKAL--TDLSLKSSSESSDTPKMSEMSQSLETLGPSTPSDVNF
FLRSEDAQ-EEAGAKE------GASTKDR----GLGSRATFPEGFHPRRSSQGVIHMPLY
SV

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDHMLKTLPPVHIVACALDPMLDDSV--MFARRLREVGQPVTLHV
VEDLPHGFLSLASLCRETQQAAQLCVER------IRLILT-------PPAAPQP------
------------------------------------------------------------
----------------------

---------------TMEPDSKLVSRPDWEPEPHQTPITQSESGPEKTPTAQPA-SKAQQ
GPDTQQKRTAQ-------QRPLAQHGAESQQEPRAQQKSALQQECLAPQE-PAPQQSPPI
QRVPFRKQ-EAASQHRPGPGKDSRTQQEPELREGAGAQVGPGKM----------------
--------PPAQTELRSQERRRQS--DPTAQHAAPAQGAKSQEGSLAEWQFL----SKPN
EPSMQQPASEHKTFLERVVDSGADSDLGFTLETNSPAQ-RGGTVAQGMKPVFKGKPGYEV
MSGF--GGTSLPSKKT-----------SSQNPRRYRN----PASRLSHR

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLHTV-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFAGVREQALGLEPT-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLVHLLHKSRYVASNRRSIFFRTSHNLAELEAYLTALTQLR
ALA-YYAQHLLATNQPGKLFFEGDERVIADFLHEYITLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIVQNLDVHFW
KTFWNITEIQVLSS-LANMTSATVRV-SRLLSLPP---------------ITFEMPLTAD
PKVMVTISPPLAHTGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_6 (695, 728)

SEELSSLGRSEGPRSLELRSRPQQA-
-PRSRCL

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 1150)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGAPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQATASPSRLLSLMDPLLPLSMLSKCVN---------AYAGGE---TEDHCDSDQKALGM
VGLVQRDTALLFRDLRLGASSWLNSFLELSGQKSHPNLVPI------------AEPMRCS
VSETALAQPESPKGTDSLKGLTLHDLSLRGSSET---PDTPELSLSVEARGHSTPSAINF
LLRPEDAS-EESEAGD------ELSTKDR-------VYAAFPEGFHPRRSSHDVKRVTLY
SSPILKNPFMSPLLAPDSMLQTLPPVHIVACALDPILDDSV--MFARRLRSLSQPVTLRV
VEDLPHGFLSLAALCQETRQAAALCVER------IRLVLNAGPAGLSRG-TE--------
--------------------------ATSGEGGC--------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------ME--S
DWGS--GAARADGALASKRAKEGSKSRSRRRWRKSKT----KASRLTHS

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAYFSSQGPGET-ARRLSGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLVALTQLR
ALA-YYAQGLLATNQPGGLFFEGDDGLIAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KSFWNITEIEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PKFTVTISPPLAHSGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SEELSNLVKSEGPRSLELRPRPQQA-
-PRAQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 889)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSIMDPLLPLSVLTKCVS---------AYAGGE---TE

ENSGT00730000111056_0_Linker_5_7 (889, 1086)

DPSNSDQKALGM
MGLVRRDTALLFRDLRVGASSWLHSFLDLSGNKSHRNSVPT------------AEPMRRS
VSEAALVQPEGPLGTDSLKSLTLHDLSLKGSSDT---SDTPELSLSAETLGPPTPSDINF
FVGPDDAP-D------------ELSTKDR----GCSASAAFPEGFHPRRSSHSTTRMPLC
SLPIV

PF07859 // ENSGT00730000111056_0_Domain_7 (1086, 1149)

KNPFMSPLLASDSMLQSLPPVHIVACALDPMLDDSV--MFARRLRGLGKPVTLRV
VEDLPHGFLSLAALCQETRQAAEQCVEC------IRLILAPPAAPRV-------------
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETHAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHV
KRVPLTQQ-EPASQQGPGLGKESTTQQELALRERHVAQPGSGPGEPPPVQQEAESTPETQ
AKPGAKREPSDPTESTSQETPEQSD-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-IGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKA------------SAQNHRHYQD----TASKLIYNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QVSPLHLV
AP------GLAYNMWSALSDSANSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--SDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPIDR----GLGVNAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IPAR-------------RIRA-----
----------ARGD-----------------GGCGGRH----------------------
----------------------

-MKAGRPTSLTRETATTEPGSTSVSRPHWEPELHQRPTVQPEPGPEKILT-AQLGSKTLQ
EFSSQQKQG------L-QHEPTAQHKAEFQQEPRAQYKFALLQKFLAPLASPAPQQSSSN
HSMHMDQP-EATSHQGPGPV--TTTPPVPQLKEGLEALPTSRPVEPSLAQQEAESTSTAQ
VTPESKVRPPTQTESTSQETPEQSAP--TAQPTPPVQGTQSKNRSLNEWEFL----TRLH
ELSIQRTAQEWKTFFDWVTDSDTED-LNSSSESDSSAQ-KSGTVTPG---AFKKKPDYQT
VSGY--GGTSPYGKEN-----------SIQSHKHYQG----TASAFSHGMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSSIFAGVREQALGLEPI-LGRLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQRLLTTNRPGVLFFEGDERITADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRI-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKMLNNLVKSEGPR-LELRPRPQQV-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VIHIHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGEQICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQPAASPSRLLSLIDPLLPLSVLSKCVS---------AYSGTE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1066)

HSDSDQKALGM
MGLVRRDTSLLLRDLRLGASSWLNSFLELSGRKSQKTPVPTA----ASDFAPPTEPMRRS
VSEAALAQPEGPLGTDSLKNLTVKDLSENSSSET---SDSTELSHSAETLGPTTPSDVNF
FLRPEDSQ-EEAEASD------EMSTMDR----SPSVHKAFPEGF

PF07859 // ENSGT00730000111056_0_Domain_7 (1066, 1149)

HPRRSSQGILRMPLY
SSPIVKNPFMSPLLAPDSMLKTLPPVHIVACALDPMLDDSV--MLARRLRDLDQPVTLNV
VEDLPHGFLSLAALCRETRQAAELCVER------IRLVLTPPAAPTPAPTAPPK------
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESK---
---TQQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PTPQQSPHV
KRVPLTQQ-EPASQQGPGLGKESTTQQEPVLRERHVAQPGSGPGEPPPVQQEAESTPAAQ
AKPRAKREPSAPTESTSQETPEQSH-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSKQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGMSPHKKT------------SAQNHRHYQD----TASKLIYNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 850)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSNNWIFSRPWAPHIYSAGAK---TEDHSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAGDQVWW
QA--------------------------------------PVI-----------------
---P--AT-QEAEAGE------SLE-----------------------------------
--------------------------------------------------------PRRR
GCNLPHGFLTLAALCRETRQAAELCVER------IRLVLTPPPPAGSGLRGEKGL-----
----------RGRH----------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MKSKPSGEDWRPGDPAGE-----------------------ERDQAVDIPQRN------
-------------------REAARLEAPGGGRSDSSA----TASRLTHSMDLHTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQHLLATNQPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRKETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMTSTTVRV-SRLLSLPP---------------EAFEMPLTAD
PKLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKELNSLVKSEGPRSLELRPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 891)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGTPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTMSLRAAAFGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLTKCVS---------AYAGGE---IEDH

ENSGT00730000111056_0_Linker_5_7 (891, 1085)

SDPNQKALGM
MGLVQRDTALLFRDLRLGASSWLHSFLDLSGHKSHTNSVPM------------AEPMRRS
VSEAALAQPEGPLGTDSFKSLTLHDLSLKGNSDT---SGSPELSLSAETLGPSMPSNVNF
LPGPDVRK-DAKA-PG------ELRAKDR----GQGVLANFPEGFHPRRASQGPTRMPIY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDSMLQSLPPVHIVACALDPMLDDSV--MFARRLRGLGKPVTLCV
VEDLPHGFL---------------------------------------------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MDLHSI-T

PF06350 // ENSGT00730000111056_0_Domain_0 (358, 694)

QSL
V-TLAED---NMAFFSSQGPGET-ARRLSSVFAGVREQALGLEPA-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKCRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYGQRLLAINRPGGLFFEGDEKITAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRI-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLIRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELNSLVKSEGPRGLELRPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 887)

VIHIHGGGFVAQTSRSHEPYL-KGWAQELGAPIVSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPVTT
LQSAASPSRLLSIMDPLLPLSVLSKCVS---------AYSGAE---

ENSGT00730000111056_0_Linker_5_7 (887, 1065)

TEDQSDSDQKALGM
MGLVRRDTSLLLRDLRLGASSWLNSFLELSGRKSQKSSIAPV----VPDSAPPTESMRRS
VSEAALAQPECPL--------TLKELSLKGSSEA---TDTPEMSLSVETLGPNTPSDVNF
FLRPEHPR-EEDEVKE------ELNPKDR----SQGVSNAFPEG

PF07859 // ENSGT00730000111056_0_Domain_7 (1065, 1149)

FHPRRSSQGAIRMPLY
SAPIVKNPFMSPLLAPDSMLKTLPPVHMVACALDPMLDDSV--MFARRLRGLGQPVTLRV
VEGLPHGFLSLAALCRETRQATELCVER------IRLVLSPPPAAPPP------------
------------------------------------------------------------
----------------------

----------------VEPTSNSVSKSN---EPEPRQPTQPDPGPEKTLMTQP-GAKTQQ
ESNSQQEPASQQRPLLSPQEPLAQHEAESQQEPGTPQE-------------PASQQSPSI
QEEPFTQQ-EAASNQ---GGKDLTLHPAPELRDEPTAQPGPRSLKSPLAQLATESPPRIQ
PRPAPKRGSSAQSESTTQNTPYQP--------QTSTFSARSQQRAFNEWGFL----TKLQ
ELSLQRSAAEWKTFFEWATDSDSESDRVSSVDTDLSKM-QEDLTTQGRRPSFKGKPGYKG
KSGY--SGTSPPKKTNQ-------------KYSYYQGTXXXXXXXXXXXXXXXXX-XXXX
X-XXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXX-XXX----X---------------XXXXXXXXXX
XXXXXXXXXXXXXXXX--XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXX-XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTFRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYSGVE---TEEHSDSNQKALGV
MGLVRRDTALLLRDLRIGASSWLNSFLEFSGRKSHKTSAPMAE----------PIPMRRS
VSEAALAQPEGPLGPDPIKSLTVQDLSLKGSSEV---SHACNTSLSAETLGPSKPSDVNF
LLGPEEVSEEAEEVSEEAETINKLHSPDRSLGSGPCASAAFPEGFHPRRSSQAVTQMPLY
FSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1150)

AKNPFMSPLLAPDCMLEGLPPVHLVACALDPMLDDSV--MFARRLRSLGQPVTLHV
VEDLPHGFLSLATLCRETREAAALCVER------IRQVLAPPAPPSAPGAGR--------
-------------------------------GRGGGRH----------------------
----------------------

----------------MEPGSKSVSRSDWQPEPHQRPITPPEPGPEKTPI-AQPESKTLQ
GSNTQQKPASNQRPLT-QQETPAQHDAESQKEPRAQQKSASQEEFLAPQK-PAPQQSPHI
QRVPLTQQ-EAASQQGPGLGKESTTQQEPALRQRHVGQPGPGPGEPPPAQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSNQGSLTELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPAT-MGGMVAQGVKLGFKRKSGYKV
MSGY--GGTSPHEKT------------SARNHRHYQD----TASRLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSCYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLIKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSRSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLENLTLRDLSLRGNSETS--SDTPEMSLSAETLSPSTPSDVNF
LLPPEDAG-EEAEAKN------ELSPMDR----GLGVRAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDNMLKSLPPVHIVACALDPMLDDSV--MLARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPP--AGAGPSGETGA-----
----------AGVD-----------------GGCGGRH----------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M-ESTG-GSGPTGAQASKNE---
---------KEELKSR-----------SRRRWRKAKA----KASRFMHTMDLHTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLTSVFAGVREQALGLEPA-LVRLLGVAHLFDLD
SET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLVALTQLR
ALA-YYAQHLLATNQPGGLFFEGDERLTAEFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASVTVRI-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLIRL-ISYELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEAISNLVKSEGPWSLELRPRHQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

HSGSDEKALGM
MGIVRRDTSLLLRDIRLGASSWLNSFLELSGHKSQKKPVPV------------AEPIRRS
VSEAALAQQESPLDTDSLKGL--KNLSLKGYSESSDTSKLSEMSQSLEALAPSKPSEVNL
FLRPEDAL-EEAEANE------ALSTKDR----GPGSPATFPEGFHPRRSSQGPIHMPLY
SAPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDHMLKTLPPVHIVACALDPMLDDSV--MFARRLRALGQPVTLRV
VEDLPHGFLSLASLCRETRQAAQLCVER------IRLILT-------PPAAPAHP-----
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHV
KRVPLTQQ-EPASQQGSGPGKEFTTQQETALRERHVAQPGSGPGEPPPVQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSH-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSKQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLIKSNSQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 966)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYA--------------------
------------------------------------------------------EPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--LDTPEMSLSAETLGPSTPSDVNFLLPPEDAE-EEAEAKN------KL

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 966)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYA--------------------------------------------------------------------------EPMRRSVSEAA

ENSGT00730000111056_0_Linker_6_7 (966, 1082)

LAQPQGPLGTDSLKNLTLRDLSQRGNSETL--LDTPEMSLSAETLGPSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPMDR----GLGVNAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLA------------------------------------------------
------------------------------------------------------------
----------------------

-----------------EPDSALASRPEWKPETQQRPIIQPDRGPETTPT-EHPGPKMLP
EFDTPQKQS------L-PQEPAAQHGAGFQQEPRVPQKSPVLQKILAPFASPAPQQSAAS
QKPPLDQQ-GAASLGGPEAEKVSTAQQEPQLREEHVWMRGPGPAKPPEEPHEAEAASAAQ
AGPGPQQNPPAQIYSASQETLEHTDP--TAPQTPLVPEAKPKQGSLMESGFL----TRLH
ELSIQRTTQEWKTFFDWITESDTEEHVSSSSKANLPEP-KAGMVILGMPLPSKKKADCEK
TFH--------------------------------LS----TASSFSHGMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_1 (357, 426)

TQSL
V-TLTED---NMAFFSSQGPGET-ARRLSSVFAGIREQALGLEPT-LGHLLGVAHHFDLD
TET--

ENSGT00730000111056_0_Linker_1_2 (426, 540)

P------------------------------------------------------
-----------------------------------------------------------

PF06350 // ENSGT00730000111056_0_Domain_2 (540, 693)

P
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EASEMPLTSD
PKLTVTISPPLAHTGPGPVLARL-ISYDLREG

ENSGT00730000111056_0_Linker_2_5 (693, 794)

QVSPCLSLALSSLSSA-STL--------
----------------M---WASPATHL-PSWPCHLCPRLVSP---LLPSCPPP-ALLRC
QSA--MS-GPFSP

PF07859 // ENSGT00730000111056_0_Domain_5 (794, 890)

QLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQPSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---TEDHSDSDQKALGM
MGLVQRDTSLFLRDLRLGASLWLNSFLELSGRKPQKTSVSTADTVR------STESMRRS
VSEAALAQPEGLLNADTLKTLTINDLS---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQAESKT--
----QQEPDSRQRPLS-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHV
KRVPLTQQ-EPASQQGPGLGKESTTQQEPALRERHVAQPGSGPGEPPPVQQEAESTPEAQ
AKPGAKREPSDLTESTSQETPEQSD-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGAKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYN

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLHTM-TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 698)

SEE

PF10340 // ENSGT00730000111056_0_Domain_5 (698, 820)

LSSLVKSNGQRSLELWPRPQQA-
-PRSRSLIVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVAL

ENSGT00730000111056_0_Linker_5_7 (820, 1083)

RAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TEDHSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--WDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPMDR----GLGVNAAFPEGFHPRRSSQGATQMPLY
SS

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPPAAPAPP-PAGSGL-----
----------RGGD-----------------GGCGGRH----------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 536)

MDLRAM-TQSL
V-VLAED-NAT--YFASQGPGET-ARRLAVAFTGIREQAMGLEPA-LGQLLGVAHLFDLD
PETPTPANGYRSLGHTARCCLAHLLHKARYVAGSRKSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQRLLAANRPGGLFFEGDGGLSADFLREYGTLHKGCFYGRCLGF--QISSGRCP
LPSTGSSGAVPCPPHTSFGSRGQPRLSRPQRTQGRH------------------------
AQSWGLGPARVCQGQHSNSGIPALTSPPRSGSLPLLLSKTSSTLLSGSPGLLCSFPARPC
P-SASSLSPPFLCFPPRAPFSSLSNAPPRDGGRDSEELNILARAEGPRNLELRPRTHHA-
-PRSKSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 892)

VIHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-LKNCRLLGSTGERVCLAGDSAGGNLCFTVSLRAAAYGVRLPDGIMAAYPATM
LQASASPSRLMSLMDPLLPLSVLSKCLS---------AYAGVE---PEAQE

ENSGT00730000111056_0_Linker_5_7 (892, 1058)

DQEQQALGV
MGLVKRDTALLLRDLRLGASSWLNTFLELGGRRGIDGPHG---------PPSVTETMRRS
VSEAALQEP-TDFSKESPKSLTLQDLSLVGGPTP---PG---LSSSDDTL-NS-PPEVSF
FLPSSPDEEGTEEDYE-------EEGRD----SQDRL

PF07859 // ENSGT00730000111056_0_Domain_7 (1058, 1133)

ASTFPDGFQPRRSSQGRANLSLQ
TSPIVKNPFMSPLLAHDSMLQTLPPVHIVACALDPMLDDSV--MFARRLRGLGRP-----
------------------------------------------------------------
------------------------------------------------------------
----------------------

----------------VEPGSNTVSGPDWESEPHKRPTTQPEP-----------ESKMQQ
GSNTQQKPASQPRPLT-QQELLTQHEAESQQEPRTQQKSVSQHELLAPQG-PVPQQSPPT
QRVRFTQQ-EAASQQGPGPGKDSTAKQEPELREGHVAQPGPGPVEPPLAQQETESTLTAQ
AKPGPKKGTPAQTESTCQERLEQSNP--IAQQTILIQGTKSRQEYLTEQGFL----TKLK
ELSTQQSTIEWKAFFEWVTDFDSESDVRSSSETDPLAM-RDGTVAQGVKLAFKKKPSYEV
ISGY--GGTSPHGKKT-----------SAKNHKHNQD----TASRLTHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLLGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
AET--PGNGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
AVA-YYAQRLLATNQPGRLFFEGEEGLTAEFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTTD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSRLAKSEGQWTRELWQRTQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPILSIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICVAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLTKCVS---------AYSGAE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1069)

HSDSDQKALGM
MGLVRRDTALLLRDLRLGASSWLNSFLELSGRKSQKTS------------QPVAEPMRRS
VSEAALAQPDGPLGTDSLKNLTLKDLSLRSSSDT---SDTPEMSLSAETLGSSKPSDTNF
LEGSEAAL-EEAEARN------ELRAEDR----GRGALAAFPEGFHPR

PF07859 // ENSGT00730000111056_0_Domain_7 (1069, 1149)

RSSQGATQMPLS
SSPIVKNPFMSPLLAPDSMLRTLPPVHIVACALDPMLDDSV--MFARRLRSLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLILTPPAAPRV-------------
------------------------------------------------------------
----------------------

----------------MEPGSQLVSRPDWEPEPHQRPITLPEPGPEETPT-AQPESKTPQ
GSNTQQEPASKQRPLT-RQEPPAQHDAESQKEPRAQQISALQEEFLAPQK-PAPQQSPHI
KRVPLTQQ-EAASQQGPGLGKESTTQQEPALRERHIAQPGPGPGKPPPTQQEAESIPAAQ
AKPRAKRKPPAPTECTSQETSEQSDP--ITQRTTPVQGAKSKQGSLTEPGFL----KKLQ
ELSIQPPHL---------------------------------------------------
------------------------------------P----TASRLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-ARRLSGVFEGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLIRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWTRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHFHGGGFVAQTSKSHEPYL-KSWALELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYTGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

HSNSDQKALGM
MGLVRRDTAMLLRDFRLGASSWLNSFLELSGRKSQKIS------------EPTAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSET---SDTPEMSLSAETLGPSTPSDINF
LLPPEDAG-EEAEAKN------ELSPMDR----GLGVSATFPQGFHPRRSSQGPTQMPLY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRHLDRPVTLHV
VEDLPHGFLTLASLCRETRQAAELCVER------IRLVLTPPAAPAARGDEGCGG-----
----------QH------------------------------------------------
----------------------

----------------VEPDSKLVSRPDWEPEPPQIPITQPASEPENTPTAQPA-SKAQQ
APDLPQNLTAQQR-------PLAQQETEGQQEPPAQQKSTLHQEFRAPQA-SALKPSPPI
QRVPFSKQ-EAASHPRPEPGKESRTQQTPELREGSRAQRQPEPQN---------------
-------EPPAQTEPMSQERQQQS--------DLAAQGVKSGEESLAEWQFL----SKPN
EPSEQPSTSEWKTFLEWVTDSGTKPDVGFTLDIDSPAT-QGRMAAPGKKLAFKDQPDYET
MSGF--GGMPTPRKKI-----------SSQNPRQYLY----TASRLLQR

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGEM-ARRLTGVFVGIREQALGLEPA-LGRLLSVAHLFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYV-------------NLAELEAYLAALTQLR
ALA-YYAQHLLTTNQPGRLFFEGDERVIADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGIGVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIQVLSS-LANMASTTVRV-SRLLSLPP---------------VAFEMPLTSD
PELTVTISPPLAHTGPGPVLVRL-ISYDLREGQN

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SKELSSFVTSEGPRSLELRLRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATL
LPAPASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHSDSDQKALGV
MGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVPK------------TEPMRRS
VSEAALTQPEGPLGTNSLKSLKLHDLGLRNSSDT---TDTPELSLSAEILSSSAPSTVNF
LLGSEDES-EVSEA-----------------------------------PSQGAMWMPLY
SAPIVKNPFMSPLLAPDSMLQTLPPVHIVVSA----------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

---------------IVEPGSKSVSRPGWEAELPQRPNTQPEPKPEKTPTTQSGSSKTQQ
EYNVQQEPVLQQRPLT-QQEPFAQQEAESQQETRVQQKSSS------QQE-PAPPQSPST
QRETFIQL-EAASQQ---EGKGSTSQKEPQLKAGHVVQPEPGSRKPHLVQKAAESISMAQ
PSPDLKRGPPTQIESTSRERPEQD-PDTTTQQNPLAQGAKSQQGSLTEWGFT----VKPP
EQSLQRSAAEWKTFFEWATDSESESDQKSLSETDSLVT-KEETVAQGRNLRFKRKPGYKV
MSGY--GRTSPSEM---------------KTKSHYKD----TVSRLTHG

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLHTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLLHVFAGVREQALGLEPA-LGRLLGVAHLFDLD
SET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRSSHNLAELEAYLAALTQLR
ALA-YYAQLLLSTNQPGELFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVAASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASVTVRV-SRLLSLPP---------------KAFEMPLTTD
PKLTVTISPPLAHTGPGPVLVRL-ISFDLREGQD

ENSGT00730000111056_0_Linker_0_6 (695, 728)

SEELSSLVKSEGPRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 1150)

VVHIHGGGFVAQTSKSHEPYL--SWAQELGAPILSIDYSLTPE-PIPRALK-C
F-YYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVTLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYSGGE---TEDHSDSEQKALGM
MGLVRRDTALLLRDLRVGASSWLNSFLELSGRKSHKSLVPI------------AVPIRRS
VSEAALAQPESPLGGDPIKSLTVQDLSLKTSSEV---SDASELSLSGETLGPSKPSDVNF
LLGPADAS-QESVAPD------KWRTQDRSRSTGSRASAAFPEGFHPRRSSQGATRMPLY
SSPIVKNPFMSPLLAPDCMLQTLPPVHIVACALDPMLDDSV--MFARRLRSLGQPVTLRV
VEELPHGFLSLAALCRETREAAALCVER------IRLILTPPAGPRRPGAPG--------
--------------------------AARGDGRE-GRH----------------------
----------------------

----------------MEPGSQSVSRPDWEPEPHQRPITLPEPGPEETPT-AQPESKALQ
GSNTQQEPASKQRPLT-QQEPPAQHDAESQKEPRAQQISVLREEFLAPQK-PAPQQSPHI
KSVPLTQQ-EAASQQGPGLGKESTTQQEPALRERHVVQPGPWPGNPPPTQQEAESIPAAQ
AKPGAKRKPPAPTEATSQETSEQSGP--TTQRTTPVQGVKSTQGSLTEPGFL----KKLQ
ELSIQRSALEWKAYFEMLTDSESESDMGSSSDTDSSAM-TAGMVAPGVKLALKRKSGYKV
MSGY--GGMSPHEKT------------SAQNHRHYQD----TASKLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-ARRLSGVFEGVREQALGLEPA-LGHLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPQTAN
PTLTVTISPPLAHTGPGPVLIRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYTGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

HSNSDQKALGM
MGLVRRDTAMLLRDFRLGASSWLNSFLELSGRKSQKTS------------EPTAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSET---SDTPEMSLSAETLGPSTPSDVDF
LLLPEDAG-EETEAKN------KLSPMDR----GLGVSATFPQGFHPRRSSQGPTQMPLY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLDRPVTLHV
VEDLPHGFLTLASLCRETRQAAELCVER------IRLVLTAPAPAPAPPRGETRA-----
----------AGVG-----------------GATL-------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLTGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQRLLTTNQPGRLFFEGDERVIADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGISVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIQVLSS-LANMASTTVRV-SRLLSLPP---------------VAFEMPLTSD
PELTVTISPPLAHTGPGPVLVRL-ISYDLREGQDSKELSSFVRSEGPRSLELRLRPQQA--PRSRALVVHIHGGGFVAQTSKSHEPYL-KSWAQELGAPILSIDYSLAPEAPFPRALEECFYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATMLQSTASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHPDSDQKALGVMGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVSK------------TEPMRRSVSEAALTRPEGPLGTDSLKSLKLHDLGLRNSSDT---TDTPELSLSAETLGPSAPSTINFLLGSEDGS-EMSEAPE------ELNNK-DR---VRGVGAAFPEGFHPRRCSQGAMWMPLYSAPIVKNPFMSPLLAPNSMLQTLPPVHIVACALDPMLDDSV--MFARRLRGLGQPVTLRVVEDLPHGFLSLAALCRETRQAAALCVER------IRLILNLPGPPV-----------------------------------------------------------------------------------

PF10340 // ENSGT00730000111056_0_Domain_5 (682, 819)

RL-ISYDLREGQDSKELSSFVRSEGPRSLELRLRPQQA-
-PRSRALVVHIHGGGFVAQTSKSHEPYL-KSWAQELGAPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVS

ENSGT00730000111056_0_Linker_5_7 (819, 1084)

LRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHPDSDQKALGV
MGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVSK------------TEPMRRS
VSEAALTRPEGPLGTDSLKSLKLHDLGLRNSSDT---TDTPELSLSAETLGPSAPSTINF
LLGSEDGS-EMSEAPE------ELNNK-DR---VRGVGAAFPEGFHPRRCSQGAMWMPLY
SAP

PF07859 // ENSGT00730000111056_0_Domain_7 (1084, 1149)

IVKNPFMSPLLAPNSMLQTLPPVHIVACALDPMLDDSV--MFARRLRGLGQPVTLRV
VEDLPHGFLSLAALCRETRQAAALCVER------IRLILNLPGPPV--------------
------------------------------------------------------------
----------------------

-MKPRRPTSFTREIPTAEPDST-----------------SPDPEPETTLT-DHPGAKMLQ
EFDTPKPVV------Q-LNE------AEFQQVPRVPQKSALLQKILAPLASPAPQQSSPS
QKVHLDQQ-EATSHRGPGTGKVSTTQQEPQLREEHVGMTGSGPAEPPLAPHEVEATSTSQ
AAPGPQKKSPAETHSSFQERLEQSDP--TAQQTPLVQEAKSNQGSLMESGFL----TKLH
ELSIQHTAHEWKTFFNWVTVSDTEEHLSSSSKSNLSEP-KSGTVIPEMLLPFEKKPDCEK
LPGY--GGKSPHGMKA-----------SLQNHKHYWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGHLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQRLLATNRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKMLNSLVKSEGPR-LELRPRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KNWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQPSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1083)

HSDSDQKALGM
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTSLPTPEAVRPT------ESMRRS
VSEAALAQPEGLLGTDSLKTLTMKDLSFKGNSET---SDTPEMSMSMETLGPSTPSDVNF
FLRPENFH-EEGEAKD------DVGTMDR----APRVRAAFPEGFHPRRSSQGILHMPLY
SS

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDSMLKTLPPVHIVACALDPMLDDSV--MFARRLRDLGQPVTLNV
VEDLPHGFLSLAALCRETRQATELCVQR------IRLVLTPPAAPLS-------------
------------------------------------------------------------
----------------------

-MKPRRPISFTREITTMEPSSTSVSRPEWRPEAQ------------QTLT-DYPGSRELQ
EFGIPQKQS------L-PNEATAQQGAEFQQEQ-GVQQSTLLQKLLTPLAFPVPQQSFPS
HKVHSDQQ-EATSQNGPGAGKVHTTQKELEHRDEHVGTAESGPAEPPPA-TEVEATSIAQ
AVSGPDKKLPTQTDLVSQERAEQSDP--TAQQTPLVQGVKSDQGSLIESGIL----ARLQ
KLAIQQPSQEWKTFLDCVTESDMEKYLNSSSKSNPPEP-SGGTVIPGT-LPSKQKPDCGK
MSGY--GGKLPHGKKG-----------ILQKHKHYWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-ALAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGQLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQRLLTINRPGVLFFEGDEGLSADFLQDYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKMLNSLAKSEGPR-LELRPRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KNWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCELLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQSSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1083)

HFDSDQKALGV
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPHKTPLPATETLRPTDSGRLTESMRRS
VSEAALAQPEGLLGTDSLKKLTIKDLSFKGNSEP---SDSPEMSQSMETLGPSTPSDVNF
FLRSGNSQ-EEAETRD------DISPMDG----IPRVRAAFPDGFHPRRSSQGVLHMPLY
SS

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDVMLKTLPPVHLVACALDPMLDDSV--MFARRLKDLGQPVTLKV
VEDLPHGFLSLAALCRETRQAAELCVQR------IRLILTPPAAPLT-------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------P---------------A

PF06350 // ENSGT00730000111056_0_Domain_4 (652, 695)

LFDLPLVAD
PTLTVTITPP-AHTGPGPVQMRL-ISHELREGQD

ENSGT00730000111056_0_Linker_4_5 (695, 722)

SEELLQLLLPEGTLALELRWKARPA-
-

PF10340 // ENSGT00730000111056_0_Domain_5 (722, 819)

PPSPFLVVHFHGGGFVAQTSKSHEPYL-KAWAQELGAPVLSIDYSLAPEAPFPRALEEF
TLCQNWL-ICFLPSAGSTAQKVCLAGDSAGGNLCLTVSMRAAAFGIQMPDGIMAAYPATL
MQAAASPSRLLTLLDPLLPLSVLCKCLS---------AYAGVQGMEPDPPEDPSVEKLGP
VNLVCRDTALLFRDLRLGASSLFGSLMNGKGNGAR-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

-MKPRRPTSFTREIPTAEPDSALASRPEWKPETQQRPIIQPDRGPETTPT-EHPGPKMLP
EFDTPQKQS------L-PQEPAAQHGAGFQQEPRVPQKSPVLQKILAPFASPAPQQSAAS
QKPPLDQQ-GAASLGGPEAEKVSTAQQEPQLREEHVWMRGPGPAKPPEEPHEAEAASAAQ
AGPGPQQNPPAQIYSASQETLEHTDP--TAPQTPLVPEAKPKQGSLMESGFL----TRLH
ELSIQRTTQEWKTFFDWITESDTEEHVSSSSKANLPEP-KAGMVILGMPLPFKKKADCEK
VPGY--GGKSPQGKKG-----------SLQNHKQYWD----TASSFSHGMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLTED---NMAFFSSQGPGET-ARRLSSVFAGIREQALGLEPT-LGHLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQRLLAINRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PKLTVTISPPLAHTGPGPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKMLNSLVKSEGPR-LELRPRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KTWAQELGVPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQPSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1083)

HSDSDQKALGM
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTSVSTADTVR------STESMRRS
VSEAALAQPEGLLNADTLKTLTINDLNGN--T-ET--SGTPEMSLSMETLGPSTPSEVNF
FLRPEK---EEADAKD------GVGSVDR----GPRVRAAFPDGFHPRRSSQGVLHMPLY
SS

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSV--MFARRLRDLGQPVTLNV
VEDLPHGFLSLAALCRETRQAAELCVQR------IRLVLTPPAAPLV-------------
------------------------------------------------------------
----------------------

----------------VEPGSKSVSRPDLELKPPQTPITQPEPGPKVTATAQPA-SKTHQ
RPSTPHEAAPQQRPLT-QQETLAQHGAESQQEISTQQNSPLQQKLLAPQE-PAPQQSPPM
HREPSSQE-EAASQKGPGPGKESETQQEPEMREAHVAQPGPGPAQQPPAQQEAGSTPPAQ
PRPGPKNGSPPQTESIFQERLRQS--DPIAQQRAPARGAKSQLRSLTEWGFL----SKLH
QISTQQPASEWRTFYEWVTDSDSEPDVGSPLKRSSSAK-RGGTVAQGMKLAFKGKHE--V
ASGY--GGTSAHGKK------TG-----SQNHRHYRD----TASRLTHS

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQRLLATNRPGGLFFEGDEGLITEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTTD
PKLTVTISPPVAHSGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_6 (695, 728)

SEELSSLMKSEGPRSLDLRPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 1150)

VVHIHGGGFVAQTSRSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSTASPSRLLSLMDPLLPLSVLTKCVS---------AYAGGE---TEDHSDSDQKALGM
MGLVRRDTALLFRDLRVGASSWLHSFLDLSGHKSHANSVPT------------AEPMRRS
VSEAALAQPEGPLGTDSLKSLTLHDLSLKGSSDT---SDTPELSLSAETLGPSTPSDVNF
LVGPEDAP-EAKAR-D------ELSTKDQ----GCGARAAFPEGFHPRRSSQGATRMPLC
SSPIVKNPFMSPLLASDSMLQSLPPVHIVAGSRGGRAQVHL--GKARRLRGLGKPVSLRV
VEDLPHGFLSLAALCRETRQAAAQCVEC------IRLIFALPAPPAAPRV----------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MSRWSKW----PHPG
-------------------------------------Q-AG------------PSPGLSP
QAAT---GTS-HSRQS-----------QPWGALKRPG----RASRLTHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSGQGPGET-ARRLSGVFAGIREQALGLEPA-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQRLLAINRPGKLFFEGDEGVTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------KAFEMPLTAD
PKLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVRSEGPRGLELRPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCGLLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGGE---MED

ENSGT00730000111056_0_Linker_5_7 (890, 1065)

HSDSDQKALGM
MGLVRRDTALLFRDLRLGASSWLNSFLELSGHKSRPNLVPT------------EEPMRRS
VSEAALAQPEGPLGTDSLKYLTLHDLSLS--SET---QDTPELSLSAETLGPTTPSAVNF
LFRPEDAP-EEAEARD------EISTKEEK---VYSVRAAFPEG

PF07859 // ENSGT00730000111056_0_Domain_7 (1065, 1149)

FHPRRSSQGAIQMPLY
SAPIVKNPFMSPLLAPDSMLQTLPPVHIVACALDPMLDDSV--MFARRLRSLGQPVTLHV
VEDLPHGFLSLAALCRETRQAAALCVDR------IRFILNPPGPATPAG-PT--------
--------------------------TPPV------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------

PF06350 // ENSGT00730000111056_0_Domain_0 (379, 695)

GPGET-ARRLLGVFTGVREQALALEPA-LGHLLGVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLATLTQLR
ALT-YCAQRLLT------SFFEGDEGLAADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-SX-----------------P---------------PEAFMPLTAD
PKLTVTISPPLAHTGPGPVLVRL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_6 (695, 728)

SEQLNSLVKSEGSRSLELWPRPQQA-
-PRSPSL

PF07859 // ENSGT00730000111056_0_Domain_6 (728, 1150)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGVPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQFTASPSRLLSLMDPLLPLSVLSKCVS---------AYAGGE---TEDHSNSDQKALGM
MGLVRRDTALLLRDLRLGASSWLNSFLELSGHKSHPKSVPV------------AEPVRRS
VSEAALAQPEDPVGTDPLKSLTVHDLSLRGNSET---SDTPELSLSDETLGPSTPSDVNF
LLGPEDAP-EKVGSQE------ELSTKDRS---SSCLSATFPEDFLPRRSSQGPTQIPLY
SSPIAKNPFMSPLLAPDSMLQTLPPVHIVACALDPILDDSV--MFARRLRSLGKPVTLRV
VEDLPHGFLSLASLCRETRQAAALCVER------IRQILTPPGPAAAGLSRQ--------
--------------------------PEPAAGGCGGRH----------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITQPEPGPEKTPI-AQPESKTLQ
GSNTQREPASNQRPLT-QQETPAQHDAESQKEPRAQQKSASQEEFLAPQK-PAPQQSPHI
QRVLLTQQ-EAASQQAPGLGKESTTQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSKQGSLTELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPAT-MGGMVAQGVKLGFKRKSGYKV
MSGH--GGTSLHEKT------------SARNHRHYQD----TASRLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAN
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIVSIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCTLLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLRNLTLRDLSLRGNSETS--SDTPEMSLSAETLGPSTPSDVNF
LLPPEDAG-EEAEAKN------ELSPMDR----GLGVHAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MLARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPPPPAGAGPRGETGL-----
----------RGAT-----------------L----------------------------
----------------------

-MKPRRPISFPGEITTMDPSSPSVSRPEWKPETQERPIIKPDPGPETTLR-DYPGSKMLQ
ESGTPQKQS------L-PNEPTAQQEAEFQQEQ-GIQQSALLQKFLTPFAFPAPQQSSPS
QKVHLDQPEEAISPNGPGAGKVYTTPKEPQLGEEHMGMTKSGPAEPPPA-TEAETTSTAQ
AVSGSDKKPSTQTNLVSQEGAEQSDP--TAQQTPLVQGAKSKQGSLTESGFL----TRLH
DLSIQQTSPEWKSFFDCVTESDIEKCLSSSSKSNPPKP-SYGTAILETALLSKKKPDFEK
LSGY--GGKLPHGKKG-----------ILQKHKHYWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGQLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRKSIFFRASHNLAELEAYLAALTQLR
AMA-YYAQRLLTINRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PRLTVTISPPLAHTGPAPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKVLNSLAKSEGPR-LELRPRPHQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 889)

VVHIHGGGFVAQTSKSHEPYL-KNWAQELGVPIFSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQSSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---AE

ENSGT00730000111056_0_Linker_5_7 (889, 1083)

DHFDSDQKALGV
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTTSPTTESVRPT------ESMRRS
VSEAALAQPEGLLGTDTLKKLTIKDLS---NSEP---SDSPEMSQSMETLGPSTPSDVNF
FLRPGNSQ-EEAEAKD------EVKPMDG----VPRVRAAFPEGFHPRRSSQGVLHMPLY
SS

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSV--MFARRLRDLGQPVTLKV
VEDLPHGFLSLAALCRETRQATEFCVQR------IRLILTPPAAPLN-------------
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTSI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PTPQQSPHV
KRVPLTQQ-EPASQQGPGLGKESTTQQEPVLRERHVAQPGSGPGEPPPVQQEAESTPAAQ
AKPRAKRGPSAPTESTSQETPEQSH-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSKQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGMSPHKKT------------SAQNHRHYQD----TASKLIYNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1076)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSEML--SDTPEMSLSAETLGPSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPMDR----GLGVNAAFPEGFHPRRSSQGAT

PF07859 // ENSGT00730000111056_0_Domain_7 (1076, 1149)

QMPLY
SSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPPAAPAPP-PV---------
------------------------------------------------------------
----------------------

-MKPRRPTSFRREIPTAEPDSTSVSRPEWKPETQQRPI-------------------MLQ
EFGTPQKQS------L-LQEPIAQHGVECQQEPRVPQKSPLLQQVLAPLASPAPQQPSPV
QKVHLDQQ-EATSHWGPEAEKVSTTQQDPQLTEDHVWMPGSGPAEPLQAPGEMEATPTAQ
AGPGPQQKSSTQIYSPSQERPEQTAP--TTQQTPPVHEVKSKQGSLTESGLL----TRLH
ELSIHRTAQEWKTFFDWITESDTEEHLSSSSKSSLPEP-KSGTVILGMPLPFKKKPDCEK
MPGY--GGKTPHGMKT-----------SLQNHKHYWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLTED---NMAFFSSQGPGET-ARRLSNVFAGIREQALGLEPT-LGHLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQRLLAINRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRKETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------DAFEMPLTSD
PKLTVTISPPMAHTGPGPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKMLNSLVKSEGPR-LELRPRPQQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KTWAQELGVPIFSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERVCLAGDSAGGNLCVTVSLRAAAYGVRVPDGIMAAYPVTT
LQPSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

HSDSDQKALGM
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTSPVSA---LPLEAVRPTETMRRS
VSEAALAQPEGLLGTDTLKTLTIKDLNSKDNSET---SDTPEMSLSMETLGPSTPSDVNF
FLRPENSQ-EETESKD------DVGSLGR----SPRVRAAFPEGFHPRRSSQGILHIPLY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSV--MFARRLRDLGQPVTLNV
VEDLPHGFLSLAALCRETRQAAELCVQR------IRLVLTPPAAR---------------
------------------------------------------------------------
----------------------

----------------VEPGSKSVSRPDGKLEPQQMLITQPEPKAEKTPTAQT-GLNTQQ
ESSTQQNPASQQTLLT-QQEPSVQHETESQQEPRALQKFASGQECLAPQN-PEPQQLPPM
QWVPFTQQ-KVASQQGPGPKKASTTQHKPELREDHRVQPGL---RTPLTQQETKSIPTTQ
ANPGPKKEPPAQIESISQEESKQSDV--TAQQESPVQEAKYEQGSLTKQEFL----AKPH
---EQQSTPKWKTLFEWVTHSDPELDMGSPSDTESPLTRKSGTVALEVKLGYIGKSGYEV
ASGY--SGISSYRNKA-----------GSQNHRHYRDTXXXXXXX

PF06350 // ENSGT00730000111056_0_Domain_0 (346, 695)

XXXXXXXXXX-XXXX
X-XXXXX---XXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTSGRFAIDPELRGA-EFDRITQNLDVNFW
KGFNI--DIELLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTTD
PKLTVTISPPLAHTGPGPVLVRL-ISYDLRDGQD

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SKELSRLAKSEGPRSLELRPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 794)

VIHIHGGGFVAQTSKSHEPYL-KTWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKNCALLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-------XXXXXX--XXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXKALGI
MGLVRRDLALLLRDFGMGASSWLNSFLELSGRKPPKPTVPTA------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

----------------EETETKSVPSANWEPESHQTPRTKPQLEPEKIPEASP-ACETQQ
GPNITQEPASLQRALP-------RQEYESPQEPKTQSNSAGQQKCLSPEE-PVRQQSPSX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX----
---X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-----------------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX------XXXXXXXXX----XXXXXXXXXXXXXXXXXXXXX

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 695)

XXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXETPANEYRSV-HTARCCA--HLHKSRYVVSNRRSI-FRTQHNLAELEAYLAAATQLR
VVA-YYAQQLLATNQTGGLFFEGEEEVLSEFLREYVRLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYRRNDTGLGGAASSLFTSRRFVIDPXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXXXXXXX-XXXXXXXX--
X-XXXXXXXXXXXX--X--XXXXXX--XXXXXXX

ENSGT00730000111056_0_Linker_0_6 (695, 732)

XXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXX

PF07859 // ENSGT00730000111056_0_Domain_6 (732, 1150)

HGGGFVAQTSKSHEPYL-KSWAQELGAPIVSIDYSLAPEAPFPRALEEC
FYAY-----------GSTGERICLAGDSAGGNLCLTVSLRAASYGVRVPDGIMAAYPATM
LQTTASPSRLLSLIDPLLPISVLSKCAS---------AYAGGE---AEKSS-SSEEALGM
MGLMRRDTARFLRDFRLVTSSWLNSFLELSEQMVRKT------------EDNKAEPMRRS
VSEAALAQQHDPLGTDSLKNLTLHDLSHKGSSET---SDTSELSLSAETLGPSKPSEVNF
LLGSEDASLDAKE--G-------PQLAD----RATGVNSAFPPGFQPRFSSQGAPQMPLD
SSPIAKNPFMSPLLAPDSMLQTLPPVHIVXXXXDPLLDDSV--MLARRLRGLNRPVTLRV
VEDL--GFLSLGALCQETRKAAALCVER------IRRIITLPASSATRPSRTSE------
------------------------------PAGAGGRH----------------------
----------------------

-MKPGRPSSSLREITTEKPSSKSTSGPEWETEPNQRPITQPEPQPEKIPAAQPG-PKTQQ
GSNTQQEPASYQRPLA-QQEFPAQ--YESQQKPRAQQKSALQQEFRAPQK-HAPQQSPPI
QRVTFVQQ-EAASQQGSGTEKEPKTQQEPELREGHVTQTGPGPVEPPVAQEGAESIPTAQ
PEPGPEKAPPAQIESTSQEKPGQD-PDHTAQQTSPAQGAKSQQGLFTEWGFL----AKLQ
DLACQRSAPEWKKAFEWVTDSATELDLGSRFGKDSLAM-SRGMVAQGMKLAFKGKPGYEM
LSGY--GGTSPHGKTI-----------NSQNHSHHQD----TASQLIQG

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLHTV-THLL
V-ALAED---NMAFFSSQGPGET-ARKLVRVFAGVQEQALGLEPA-LGRLLGVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKCRYVAANRRSIFFRTSHNLAELEAYLAALTQLR
ALA-YYAQRLLTTNQPGGLFFEGDERITAEFLSEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISVGLVSFGEHYRRNETGLSVTASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EPLEMPLTAD
PKLKVTISPPVAHTGPGPILARL-ISYDLREGQD

ENSGT00730000111056_0_Linker_0_5 (695, 728)

SEELIKLVKSEGPRGLELWPRH-QV-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 888)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGAPILSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSFRAAAYGVRVPDGIMAAYPATM
LQPTASPSRLMSLMDPLLPLSVLSKCVS---------AYAGEE---T

ENSGT00730000111056_0_Linker_5_7 (888, 1086)

ENPSNPDQKALGM
MGLVQRDTAVLFRDLCLGASSWLNSFLELSGQKSRKTPVPG------------AEPMRRS
VSEAALAQPDDTVGTNLFKSMPLQVLSPTGSSET---SEPPTLSLSAETLGPSKPSDVNF
LLRPEDAV-EDEA-----------RAQAGRLGLGHCASSAFPEDFHPRLSNQGATRIPLY
SAPIV

PF07859 // ENSGT00730000111056_0_Domain_7 (1086, 1149)

KNPFMSPLLAPDSMLQSLPPPPPQACALDPMLDDSV--MFARRLRSLDQMVTLRV
VEDLPHGFLSLAPLCRETRQAAALCVER------IRLVLNPPSSSMST------------
------------------------------------------------------------
----------------------

----------------MEPGSKSASRPDWQPEPHQRPITTPEP--EKTPI-AQPESKT--
----QQEPDSRQRPLT-QQETPAQHDAESQKDPRAQQKSASQEEFLAPQK-PAPQQSPHI
KRVPLTQQ-EPASQQGPGLGKESTTQQEPALRERHVAQPGSGPGEPPPVQQEAESTPEAQ
AKPGAKREPSDPTESTSQETPEQSD-----QQTTPVQGAKSKQGSLIELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESEVGSSSDTESLAT-MGGMVAQGVKLPFKRKSGYKV
MSGY--GGTSPHKKT------------SAQNHRHYQD----TASKLIYNMDLHTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCVAHLLHKSRYVASNRRSIFFRTNHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEMEVLSS-LANMTSATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1074)

HSNSDQKALGM
IGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSQRGNSETL--SDTPEMSLSAETLSSSTPSDVNF
LLPPEDAE-EEAEAKN------KLSPMDR----GLGVNAAFPEGFHPRRSSQG

PF07859 // ENSGT00730000111056_0_Domain_7 (1074, 1149)

ATQMPLY
SSPVVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPPAAPAPA-PAPPLV-----
------------------------------------------------------------
----------------------

-MKPRRPISFPREMTTMDPSSTSVSRPEWKPETQERPVTKPDPGPETTLT-DHPASKMLQ
GSGTPQKQN------L-PNEPTAQQEAEFQQEQ-GSQQSTLLQKFLTPLAFSAPQQSSPN
QKVHLDPP-EAIPPNGPGTGKVCTTQKEPQLREEHMGMTKSGPAEPPLA-TEVETASTAQ
AVSGQDKKPSTQTNLVSQEGPEQSDP--TAQQTPLVQGAKFKQGSLTESGFL----TRLQ
ELSIQQTSPEWKSFFDCVTESDTEKHLSSSSQSNAPKP-SCGTVIPEMALLSKKKPEFEK
MSGY--GGKIPHGKKA-----------ILQKHKHYWD----TASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGQLLSVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRKSIFFRASHNLAELEAYLAALTQLR
AMA-YYAQRLLTINRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPFTSD
PRLTVTISPPLAHTGPGPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKVLNSLAKPEGPR-LELRPRPHQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHIHGGGFVAQTSKSHEPYL-KNWAQELGVPIFSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQSSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---AED

ENSGT00730000111056_0_Linker_5_7 (890, 1083)

HVDSDQKALGV
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGHKPQKTTSPTAESVRPA------ESMRRS
VSEAALAQPEGLLGTDTLKKLTIKDLS---NSEP---SDSPEMSQSMETLGPSTPSDVNF
FLRPGNSQ-EEAEAKD------EVRPMDG----VPRVRAAFPEGFHPRRSSQGVLHMPLY
SA

PF07859 // ENSGT00730000111056_0_Domain_7 (1083, 1149)

PIVKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSV--MFARRLRDLGQPVTLKV
VEDLPHGFLSLAALCRETRQATEFCVQR------IRLILTPPAAPLN-------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MEPAVES
APVG--AQASKQGKEG-----------SKNRSRRRWRKGKIKASAFSHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSNVFAGVREQALGLEPT-LGQLLGVAHHFDLD
TET--PANGYRSLVHTARCCLAHLLHKSRYVASNRKSIFFRASHNLAELEAYLAALTQLR
AMA-YYAQRLLTINRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMASTTVRV-SRLLSLPP---------------EAFEMPLTSD
PRLTVTISPPLAHTGPAPVLARL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKVLNSLAKSEGPR-LELRPRPHQA-
-PRSRAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 889)

VVHIHGGGFVAQTSKSHEPYL-KNWAQELGVPIFSIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTT
LQSSASPSRLLSLMDPLLPLSVLSKCVS---------AYSGTE---AE

ENSGT00730000111056_0_Linker_5_7 (889, 1084)

DHFDSDQKALGV
MGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTTSPTAESVRPT------ESMRRS
VSEAALAQPEGLLGTDTLKKLTIKDLS---NSEP---SDSPEMSQSMETLGPSTPSDVNF
FLRPGNSQ-EEAEAKD------EVRPMDG----VPRVRAAFPEGFHPRRSSQGVLHMPLY
TSP

PF07859 // ENSGT00730000111056_0_Domain_7 (1084, 1149)

IVKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSV--MFARRLRDLGQPVTLKV
VEDLPHGFLSLAALCRETRQATEFCVQR------IRLILTPPAAPLN-------------
------------------------------------------------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
LRGT--GNIGATGAQALKR----AKEGTGIRSRRRWRKGKAKASRLTHG

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 695)

MDLRTM-TQSL
V-TLAED---NIAFFSSQGPGET-ARRLLGVFAGVREQALGLEPT-LGRLLGMAHLFDLD
SET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRSGHNLAELEAYLAALTQLR
ALA-YYAQRLLITSQPGRLFLEGDEGLTADFLREYVTLHKGCFYGRCLGF--QVSLLGPR
CRHLVAPNVSFFSNHCRLSS-TLHPPETTLRDAVHLSTESEARPESPQTHAGSGLRTQRI
GGFWAIGSEQRPNMALSGISAGSASP-QHLREPQQ---------------EYLELGVCSL
ESLTAPILPHISVLACGPACPQQ-PSPGIPRNLS

ENSGT00730000111056_0_Linker_0_6 (695, 726)

SPGLNSQTLSS-QPGIPLSASPHLC-
-PLSA

PF07859 // ENSGT00730000111056_0_Domain_6 (726, 1150)

ALCTYDRAWRVAPIKHRSNQPSL-SGWC-----PSXSIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATM
LQSSASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAE---TEDHSDSDQKALGM
MGLVRRDTALLLRDLRMGASSWLNSFLELSGRKSHKTSVPIAE--------PVPVPMRRS
VSEAALAQPEGPLGGDPVKSLTMQDLSLRSSSEA---SDTPKLSLSGETLGPSKPSDVNF
LLGPEDVP-EAAVAMD------EVRTQDH----CRGTSTAFPEGFHPRRSSQGATRMPLD
SSPIVKNPFMSPLLAPDYMLQSLPPVHIVACALDPMLDDSV--MFARRLRSLGQPVTLRV
VEDLPHGFLSLAALCRETREAAALCVER------IRLVLTPPGTSAP-------------
------------------------------------------------------------
----------------------

----------------VEPGSKTVSRPDWEP--HQTPITWPESGPEKTPTATA--SEAQQ
GPNTQEEPASQQGPIT-QQEPFAQHEAEAQQEPQDQQKSALQQEFLAPQE-PAAEQSPPT
QRVPFTKQ-EAASQHRPRQGKEPRTQQEPELRKGPGTQPGH-------------------
---GLKNELPGQTEPMSQQRWQQSDP--TAQHIAPAQGVKSPKGSLAQWHFL----SKPK
EPFIQRSSLELKTLLEWVTDSGTESDLRSSLETDSSAK-RDGTVAQGMKLAFRGKPGYEV
MSGF--GGTPVPRKKT-----------SSQNPRHYRN----TASRLTHSM-

PF06350 // ENSGT00730000111056_0_Domain_0 (352, 698)

LRTM-TQSL
V-TLAED---NMAFFSSQGPGET-ARRLSGVFAGVREQALGLEPA-LGHLLSVAHLFDLD
AET--PANGYRSLVHTARCCLVHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQHLLATNRPGRLFFEGDEGVTADFLREYVTLHKGCFYGRCLGFQXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXX-XX-----X---------------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XX--XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-------XXXXXXXXXXXXXXXXXXX---------XXXXXX---XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPMRRS
VSEAALAQPEGLLGMDSLKSLTLHDLSLRGSSET---ADTPELSLSAETLGPSTPSAVNF
LLGPEDAP-EEAEARDE---PRELSTKDR----VCSVGSAFPEGFHPRRSSQGSIRMPLY
SLPIVKNPFMSPLLAPDSMLQTLPPVHIV-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

----------------MEPGSQSVSRPDWETEPHQRPKTLPEPGPEETPT-AQPESKTPQ
GANTQQEPASKQRPLI-QQEPPAQHDAESQKEPRAQQISALQEEFLAPQK-PAPQQSPHI
KGVPLTQQ-EAASQQGPGLGKESTTQQEPALRERQVAQPGPGPGKPPPTQQEAESIPAAQ
AKPGAKRKPPAPTESTSQETSEQSDP--TTQRTTPVQGAKSKQGSLTEPGFL----KKLQ
ELSIQRSALEWKAYFEWVTDSESESDMGSSSDIDSSAM-TAGMVVPGVKMALKRKSGYKA
MSGY--GGTSPHEKT------------SAQNHRHYQD----TASKLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-ARRLSGVFEGVREQALGLEPA-LGRLLSVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTGHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNQPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEIEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLIRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLVKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

VVHFHGGGFVAQTSKSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-VKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYTGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1085)

HSNSDQKALGM
MGLVRRDTAMLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPTAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSET---PDTPEMSLSAETLGPSTPSNVDF
LLPPEDAG-EEAEARN------ELSPMDR----GLGVSATFPQGFHPRRSSQGPTQMPLY
SSPI

PF07859 // ENSGT00730000111056_0_Domain_7 (1085, 1149)

VKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MFARRLRNLDRPVTLQV
VEDLPHGFLTLASLCRETRQAAELCVER------IRLVLTPPAAPAPAPETRAAG-----
----------ATL-----------------------------------------------
----------------------

----------------MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPI-AQPESKTLQ
GSNTQQKPASNQRPLT-QQETPAQHDAESQKEPRAQQKSASQEEFLAPQK-PAPQQSPYI
QRVLLTQQ-EAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSKQGSLTELGFL----TKLQ
ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPAT-MGGMVAQGVKLGFKGKSGYKV
MSGY--SGTSPHEKT------------SARNHRHYQD----TASRLIHNMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NIAFFSSQGPGET-AQRLSGVFAGVREQALGLEPA-LGRLLGVAHLFDLD
PET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLR
ALV-YYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGA-EFERITQNLDVHFW
KAFWNITEMEVLSS-LANMASATVRV-SRLLSLPP---------------EAFEMPLTAD
PTLTVTISPPLAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEELSSLIKSNGQRSLELWPRPQQA-
-PRSRSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 890)

IVHFHGGGFVAQTSRSHEPYL-KSWAQELGAPIISIDYSLAPEAPFPRALEEC
FFAYCWA-IKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATM
LQPAASPSRLLSLMDPLLPLSVLSKCVS---------AYAGAK---TED

ENSGT00730000111056_0_Linker_5_7 (890, 1082)

HSNSDQKALGM
MGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMS------------EPIAEPMRRS
VSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETS--SDTPEMSLSAETLSPSTPSDVNF
LLPPEDAG-EEAEAKN------ELSPMDR----GLGVRAAFPEGFHPRRSSQGATQMPLY
S

PF07859 // ENSGT00730000111056_0_Domain_7 (1082, 1149)

SPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSV--MLARRLRNLGQPVTLRV
VEDLPHGFLTLAALCRETRQAAELCVER------IRLVLTPP--AGAGPSGETGA-----
----------AGVD-----------------GGCGGRH----------------------
----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQSL
V-TLAED---NMAFFSSQGPGET-ARRLTNVFAGVREQALGLEPA-LVRLLGVAHLFDLD
PET--PGNGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAAITQLR
ALA-YYAQHLLATNQPGVLFFEGDERLTAEFLREYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFTGGRFAIDPELRGA-EFERIIQNLDVHFW
KAFWNITEIEVLSS-LANMTSATVKV-SRLLSLPP---------------EPFEMPLTSD
PKLTVTISPPLAHTGPGPVLIRL-ISYELREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSEALSSLVKSEGPWSLDLRPRPQHA-
-PRSQSL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 888)

VVHFHGGGFVAQTSKSHEPYL-KIWAQELGVPIISIDYSLAPEAPFPRALEEC
FYAYCWA-VKHCALLGSTGEQICLAGDSAGGNLCFTVSFRAAAYGVRVPDGIMAAYPATM
LQTAASPSRLLSLMDPLLPLSVLSKCVT---------AYAGAE---TEEDSSSNQKALGM
MGIMRRDTSLLLRDLRVGASSWLNSFLELSGHKSQKKPVPL------------SEPMRRS
VSEAALAQLESPLGTDSLKTL--KDLCLKGSSELSDTPKMAEMSQSLETLGPSKPSDVNF
FLPPEDAL-EEVEAKE------GLSAMDK----GRSNRGTFPEGFHPRRSSQGPTQMPLY
SAPIVKNPFMSPLLAPDYMLKTLPPVHFVVSVDQETAVRRA--VLL----SAGDQVVRGE
AKTGPSKGGKLALWAEEAEQRAGVWLNALPPFFHLHLFIHPKSPISPPPRSPPPVAAAAM
TLPCAPPP--RGPAGMCTRPHAGRLGHVRSATACAGPAGDTARGGGSAPRLPEPGFAVPR
DSTSCPAVRGAHPPHPHSACHA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------METAGEPGSAE
AL------DLNKTNDG-----------SKAHGRRRWRKGKIKAAAFPHSMDLRTM-

PF06350 // ENSGT00730000111056_0_Domain_0 (357, 694)

TQTL
V-TLTED---NMAFFASQGPGET-ARRLSTVFAGVREQAIGLEPT-LGRLLSVAHLFDLD
AET--PANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLR
ALA-YYAQHLLATNRPGGLFFEGDEGITADFLSEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTLSIGLVSFGEHYKRNETGLGVAASSLFTSGRFAIDPELRGA-EFERIIQNLDVQFW
KAFWNITEIEVLSS-LASMASATVRV-SRLLSLPS---------------EAFEMPLASD
PNLTVTISPPVAHTGPGPVLVRL-ISYDLREGQ

ENSGT00730000111056_0_Linker_0_5 (694, 728)

DSKFLNSLVKSEGPR-LELRPRPQQA-
-ARSPAL

PF07859 // ENSGT00730000111056_0_Domain_5 (728, 900)

VVHIHGGGFVAQTSKSHEPYL-KSWAQELGAPIVSVDYSLAPEAPFPRALEEC
FFAYCWA-IKNCAML---------------------------------------------
----------------------------------------GVE---TEDQQDCDQKALGM
MGLMQRDTSLLLRDLRLGASSWLNSFLELSGRKSQKTSAPTTH---------HSEAMRRS
VSEAALAQSDSPHGTDSLKTLTMKDLNQKSSSES---SDTPEMSMSAEALGPSTPSNINF
FLRPEETPEEESEAKD------ELSPKDR----GPGAQTAFPKGFHPRRSSQGVLRMPLY
SSPIVKNPFMSPLLAPDSMLKTLPPLHIV-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

---------------TLEPGSKSVPKTDQTPESEQTPRTPPQPHPEKTAK---PRTKILQ
ESSARQEPPSQQRTAT-QQEALAQPEAKPQQQPGPQPKPTVPQQGPAASQ-ESTQPSPPI
QRLSLTPQ-EATSRQGLSPRKESTTPRKSELREDHVIKAVFEPVEFPVAQHSK-------
--HASTKGPPAQAEPASQDRRQL--PESLAQQTTPGQGANSRRESLTEXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX----------X-XX-XXXXXXX-XXXXXXXX-X
XXX-----XXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXSRLVHS

PF06350 // ENSGT00730000111056_0_Domain_0 (350, 708)

MDLHTM-TQSL
V-TVAED---NMAFFSSQGPGET-ARRLSAVFAGVREQALGLEPA-LARLLSVAHIFDLD
AET--PANGFRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTGHNLAELEAYLAALTQLR
ALA-YYAQRLLATNQPGGLFFEGDERLTADFLSEYVTLHKGCFYGRCLGF--QFTPAIRP
FLQTISIGLVSFGEHYKRNETGLGVTASSLFASGRFALNGELRGA-EL-EIIQNLGVHFW
KAFKNTES-EVRSA-LEKEAASKGKV-NPLL--PP---------------AGAXXXXXXX
XXXXXXXXXXXXX-----------XXXXXX--XXXXXXXXXXXXX-XX-XXXXXXXXXX-
-----XXXXXXXXXXXXXXXXXXXXXXX--XXXXXX--XXXXXXXXXX--XXXXXXXXXX
XXXXXXX-XXXXXXXXXXX-XXXXX-----XXXXXXXX----XXXXXX--XXXXXX----
---------XXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXGQMEEQPDSDQKALGM
MGLMRRDTALLLKDLRMSASSWLNSFLELSGRKTQKSSAPV------------PEPMRRS
VSDAALAQPEGPLGTDSLKNLTVKDLSLRSSSED-----SPEMSLSAEALGPSSPSDVNF
FLRPEDGV-QEAEARE------EQSPKNR----DQGVRAAFPEGFHPRISSQGPTQMPFY
SSPIVKNPFMSPLLAPDSMLRTLPPVHIV-------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------