Query Results 

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTD
VRGSA-------LQSLE-------------------------G-RA-----L-PHAA---
-VSSQVSY-L----------------------------------Y---------------
----LAMGPA-----------GGHGIKTPTGF-QGP----E---FSPV-------FEIQL
T----KDLICFFDSSVEL------SQQRIRMMEELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 353)

ICSPKFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSVLFYR
CRKAGSAVSKHYKVYKRPNCGRCHC--KITACRFGENNRMTYFCPHCQKENPRHV-DIC-
---------WTSSRVDH-LMDTVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCGVCTLINKPSSKSCDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIAL--
-LCCS------------------YF-----------------------------------
------------------------------------------------------------
-----------------------V-TC------------HYSKLQINMTDGPCTLNTGRP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PLCSHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHRLV--SPFVGQKVVK
TGGSSKKLNPASFQSLW--LQDARVHGKQLFLWFDPEEEM--ELLG-----SSPQP----
VQGVW--QKEAQDPELAL---GPHAQETSA-GPSG---SGEPV-PSGSDD-PCDP---RG
HNLL-AVAQRWLEVR--FG-LFGSIWVNNFSRAKKANKRGDWRDPVPR-------LVL--
-HFDGGGFLAFYSCQMSWS-------PPPEVEPTCDILS

PF06831 // ENSGT00730000110955_0_Domain_1 (280, 354)

DKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALFRAGI--HPLSLGS--LLSSSSLEALVNHVVEFSSDWLR
DKLQGK--EQHTQIYKKEQCPSGHQVMKESFGPPGRLQRLTWWCPQCQPRLPSEEP----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 259)

PEGPSVRKFHHLT--SPFVGQQVVK
TGGSSKKLNPASFQSLW--LQDTQVHGKKLFLRFDPDEET--KSPG-----NNPLPE-PL
GKGER--KKEAGDQKQTL---GPDSQKISD--QSS-------QSDSGDNG-SACL---GG
DSPA-GGAERWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPIPR-------LVL--
-HFGGGGFLAFYNCQMSW

ENSGT00730000110955_0_Linker_0_1 (259, 276)

S-------SSPVVQPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 363)

DILSEKFHRGQALEAL--GREQPVC
YTLLDQRCFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPRQLEILVDHVVEFSTDWLQ
DKFQGR--QNHTQIYQKEQCPAGHQVRKEAFGPPGGFQRLTWWCPQCQPRLPPDEPEQVQ
L----------------------------------------P------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRAQVLPGQAVTE
VRGSA-------LRSLA-------------------------A-RG-----L-PLEA---
-PGVVDAA-QAA-AQN----NKDSSQNVLQ--------LFNGYAYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSVMVNPRGSRNTK----G---LSPV-------FEVQL
T----KDLICFFDSSVELRNS-MESQQRIRMME

PF06831 // ENSGT00730000110955_0_Domain_1 (274, 355)

GLDVCSPKFSFSRAQSQVKKQQGRMLC
DVLLDQRVLPGVGNIIKNEALFDTGL--HPAVK----QLTDEQIVHLVKMIRDF

ENSGT00730000110955_0_Linker_1_2 (355, 447)

SILFYR
CNKTGSAVSKHYKVYKRPNCGQCCC--KIIVCRLGENNRMTYICPQCQKENPQLV-DVSK
LPTRNTIIGWTRWRAD--VMGSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWSCVRCTLINKPSSKVCDACLTLRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

ADS--
-VPKNEE-NSIAF-NSLVKYPCNNFGKPSTEVKINRKTAFGTTTLVLTDWSSKSSTLKGK
KSPNQIIDGEFHNSSPSNVCFM-GTRYPSNETTDY---ITQLSNKE--NRSPVGSSQSKL
FSPVHKKLKTTH-SSPDLK-SCVP-GL------------SNSELAMNVTDGPCALNAGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 700)

P
RCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFQ--------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTD
VRGSA-------LQSLG-------------------------G-RA-----P-SHAA---
-ASAPVSY-QAATLNN----NK

PF01149 // ENSGT00730000110955_0_Domain_0 (143, 249)

DSSQNFLK--------LLNGYVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSIMINPLEYKNRN----G---ISPV-------FEIQL
S----KDL

ENSGT00730000110955_0_Linker_0_1 (249, 280)

ICFFDSSVELRNS-MESQQRIRMMGEVDVCS

PF06831 // ENSGT00730000110955_0_Domain_1 (280, 352)

PKFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIRNEALFDSGL--HPAVKAC--QLTDEQTHHLVKMV

ENSGT00730000110955_0_Linker_1_2 (352, 448)

RDFSILFYR
CHKAGSAISKHYKVYKRPNCGQCHC--KITVCRFGENNRMTYFCPQCQKENPQHV-DICN
LPARNTIISWISSKVDH-LMDTVARRS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEEWTCGVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PMGK--
-MFKSEE-NLIDF-NNLVKFPCNSFRKPDREVKINRKTAFGTTTLVLSDFSNKSSTLERK
TSQSQIPEGEFSNSLPTNVCFS-DTQHPSKERTNR---LPQLSSKV--NISPAVCPESKL
FSPAHKKLKTTHYSSPDLK-SCNP-GF------------YKSELQIKMTDGPCTSNSGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHNRLCLLRVVRKDGKNKGRQFYACPLRGEAQCGFFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCSHGKRSIMRTV
LKIGPNNGKNFFVCPLAKEKQCNFFQWEENG-GIKIISGC-

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTD
MRGRA-------LQSPG-------------------------G-PG-----S-PPSA---
-SGAAGSS-QAAALNN----NKDSSQNFLR--------LFNGHIYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGFLVINPVKSKNKN----G---LPPV-------FEVQL
T----KDLICFFDSSVEIRNS-AESQQRIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPNFSFPRAESEVKKQRGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIRDF

ENSGT00730000110955_0_Linker_1_2 (355, 447)

SLLFYR
CHKAGSAVSNHYKVYKRPNCGQCCC--KITVCRLGENKRMTYFCPQCQKENAQHV-DICR
LPARNTTVSWPSSRGGH-LMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWTCEVCTLINKPSSEACDACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

TDS--
-VPKNEE-NPIAF-NSLVKYPCNSFGKPRTEVKINRKTAFGTTTLVLTDFSNKSSALGRE
ESQNQILDGEFPNP-PTNVCFSD-TVHSSKERTNY---RTQLSNKV--NISSMVCSPSKL
FSPAYKRLKTTHCSSRDLK-SGNP-GF------------SNRERQSNTPGGPRSLNACS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHDRPCVLQVVRKDGENKGRHFYACPLPREAQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCSFFQWAENGPGINIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 256)

PEGPSVRKFQLLT--SPFVGQVVVK
VGGSSQKLNVNDLNALR--LQDSQVHGKNLYLAFVAAEG--------PLGAAAGE---TA
PQREA--DCWAHCPAQ-----GQQGQAGAPQPRCQHEELQQ-PQHS-------RS---EA
PEAA-EGRGSWLRIH--FG-MFGSVRANEFSRASRANKRGDWKDPVPR-------LVL--
-HFGSGGFLVFYNCR

ENSGT00730000110955_0_Linker_0_1 (256, 297)

MLW--C-----SSPRADPASDILSVEFHRGRALRAL--CAP

PF06831 // ENSGT00730000110955_0_Domain_1 (297, 355)

DPIC
YTLLDQRHFSGLGNIIKNEILYLARI--HPLTPGS--LLAPSDLEHLLDRAIQFSSEWLH
NKLRGQ--GLHPQVYQKEQCPLGHPLRKGTFGPSGGFKRLTWWCPQCQPAVLPGDGDSSP
V-P-----E---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVKD
VRGSA-------LQSLG-------------------------G-PV-----L-PHAA---
-SLAVVST-QAAAPTN----NKDSSQNFLR--------LFSGYVYSGVQT----L----G
KELFLYFGPKALRIH--FG-MKGSIQINPFECKNKN----G---VSPV-------FEVQL
T----EDRICFFDSSVELRNS-TESQQRVRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPKFSFSRAESEVKKQKGRMLC
DVLMDQIVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHYLVKMIRDFSILFYR
CHKTGSVISKHYKVYKRPNCCQCCC--KITVCRLGENNRMTYFCPRCQKENPQHV-DIRT
LPARNTTIRRPSSRGEH-----VGRKCEEQWTCVVCLLINRPSSKTCDACT-SRPTDS--
-VIKNEE-QSTAC-NNVVKYPCNSFGKPSTELKVNRKTAFGTSTLVLSDFSNKPCALERK
TSQNQILDGEFQNPPLTNVCFR-DPLHPSEERADH---ITQPSNRV--NVSPTVFSQSKL
FSPAYKKLKTAHSSSPDLK-SGNP-RF------------SNSELGINMTDGTCALYAGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCNKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFQWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKAKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTD
LRGSA-------LQSLG-------------------------------------------
----VGSS-QAAALNN----NKDSSRNFSR--------LFNGHVYSGVQT----L----G
KELFMYFGPKALRIH--FG-MKGSIMINPLEYKNKN----G---VSPV-------LEVQL
T----EDLICFFDSSVEFRNS-TESQQRIRMMEEL

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DVCSPKFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--NPAVKAC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKTGSVVSKHYKVYKRPNCCQCCC--KITVCRLGESNRMTYFCPRCQKENPQHV-DICT
LPRRSTTDTWPSSRGDH-----VARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINRPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 662)

PPDS--
-VINNED-NSIAF-DSLVKYPCNSFGKPSTEVKVNRRTVFGTTTLVLTDFSNKSSALEGK
TSQSGMLDREFQNSPPTDVCFR-DPLHPSKERANH---RTQPSNRV--NGSPTACSQSKL
FSPAYKKLKTTHSSSPDLK-SRSP-GF------------SNSELGINMTDGTCALNAGSP
R

PF06839 // ENSGT00730000110955_0_Domain_3 (662, 704)

CGKHKLLCVLRVVQKDGENKGRQFYACPLPRQAQCGFFQWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGRRTIMRTV
LKIGPNNGKNFFVCPLGKAKQCNFFQWAENGPGIKMIPGC-

----------------------------------MVEGPGCALNGEKIRARVRPGQAVMA
VQGSA-------PQSPR-------------------------G-PG-----S-PHAA---
-SAAAVPP-QAATQNN----DSGSGGVSLR--------LLHGHVYSG-ET----L----G
KELFLYFGPKALRIH--FG-MKGYVRINPLEYKNKN----G---ISPV-------LEVQL
S----KDLICFFDSSVELRDS-TESQQRIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 360)

LDVCSPKFNFSRAEREVCKQQGRMLC
DVLMDQRVLPGVGNIIKNEALFDSGL--HPAVRVC--QLTEEQIQHLVKMTRDFSLLFY

ENSGT00730000110955_0_Linker_1_2 (360, 446)

R
CRKAGLAVSKHYKVYGRPHCGRCRS--RITVCRLGENSRMTYFCPHCQSEDARRA-DRGR
PPSRNTAVGPT-PHPDH-LGDHVAR

PF00641 // ENSGT00730000110955_0_Domain_2 (446, 476)

KWEETWACGVCTLINMPSAQACDACLAPRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

ADS--
-RLENEE-NSAAL-SDVVKYPCNGFGKPSSEVKINRKTAFGTTTLVLTDFSNKSRPLGRK
KGPHGILDGEFQSPLPTSVCLS-DTPRPSEERANN---AAQPPNTT--SLSPTV---SRL
RSPACKRQKTAHGSCPGSG-SRSP-GL------------SNRDPQMDTTDGACAPLAPV

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSQHHRLCVLRVVSKSGENKGRLFYTCPLPREAQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 752)

PLCNHGKRSILRTV
LKMGPNNGKKFFVCPLGKETQCNFFQWAT-GPGVNTTPGS-

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EAPG-----SSPPPE-PP
QKEAQ--KEGAADPKQAG---EPSGQKTPD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPPALPAVILTVRL------TKS------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLHPAAFQSLW--LQDAQVHGKKLFLRFDPDEEM--EPLN-----SNPQP----
IQGML--QKEAVDRELPL---GPSAQEPSA-GSSG---SGEPV-PSRSDE-TYNL---G-
KIPS-ADAQRWLEVR--FG-LFGSIWVNDFSRAKKANKKGDWRDPVPR-------LVL--
-HFSGGGFLVFYNCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 355)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--CLSSSSREALVDRVVEFSKDWLR
DKFQGK--ERHTQIYQKEQCPSGHQVMKETFGPPDGLQRLTWWCPQCQPQLSSKGPQNLP
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRRGQAVTD
LRGSA-------LQSLG-------------------------V-PG-----S-PPAA---
-SGAVISR-QAAALNS----NRDSSQSFLR--------LFDGLVYSGVET----L----G
KELFMYFGPKAFRXXXXXXXXXXXXXXXXXXXXXXX----------XX-------XXXXX
X----XXXXXXXXXXXXXXSS-TES-QQRTMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPKFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVRMIRDF

ENSGT00730000110955_0_Linker_1_2 (355, 447)

SILFYR
CHKAGSAISKHYKVYKRPNCGQCCS--RITVCRLGEN--TTYFCPHCQKKILQTVEHICT
LPTRNTTVNWTFSRGDP-LMDCVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWTCEVCTLINKPSSEACDACLASRH

ENSGT00730000110955_0_Linker_2_3 (476, 660)

ADS--
-VLKNEE-NPTAL-NYLVKYPCNRFGKPSTEVKINRRTAFGTTTLVLTDFSNMSRALGKE
ESQNQTPAGEFPES-PPAVCFSD-TPPPSKERTNY---KTQLSNEV--NLSPTVCSQSQL
FSPANKKMKTTQSSSPDHK-RCNP-GF------------SISELQVHVTDGPSTSNAGQ

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCRGHGRPCVLRVVRKDGENKGRHFYACPLPREAQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRCIMRTV
LKIGPNNGRNFFVCPLGKEKQCNFFQWAENGPGINIIPGC-

----------------------------------MVKGPGCTLNGEKMLARVLPGQVVTD
LQGSA-------LHDSG-------------------------S-PE-----L-PLTA---
-L--VVSC-QTAALNN----NEDSSLNFLR--------LLNGYVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSVRINPLGYENRS----G---ISPV-------FEAQL
T----KDLICFFDSSVELRNS-MESQQRIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPKFSFSRAESEIKKQKGQMLC
DVLMDQKVLPGVGNIIKNEALFDSSL--HPGVNVC--QLTDEQTHHLVKMIRNF

ENSGT00730000110955_0_Linker_1_2 (355, 447)

SILFYR
XXXAGSAISKHYKVYKRPTCCQCHC--KITVCRLGKNNRMTYFCPHCQKENPQHV-DVSK
LPIRNTIISWTPSRGHH-VMESVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWTCVVCTLINRPSSKECDACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

EXX--
-XXXXXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX---XXXXXXXX--XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXX-XX------------XXXELQINMTDGTCTLNAGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFKWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGRNFFVCPLGKEKQCNFFQWAENGPGVKSIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLHPAAFQSLW--LQDAQVHGKKLFLRFDPDEEM--EPLN-----SSPQP----
IQGMW--QKEAVDRELAL---GPSAQEPSA-GPSG---SGEPV-PSRSAE-TYNL---G-
KIPS-ADAQRWLEVR--FG-LFGSICVNDFSRAKKANKKGDWRDPVPR-------LVL--
-HFSGGGFLVFYNCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 356)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--CLSSSSREALVDHVVEFSKDWLQ
DKFEGK--ERHTQIYQKEQCPSGHQVMKETFGPPDGLQRLTWWCPQCQPQLSSKGPQNLP
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RG-----L-PPAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSVMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLVCFFDSSVELRNS-MESQRRIGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 352)

SPEFSFLRAENEVKKQKGRMLG
DVLLDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMV

ENSGT00730000110955_0_Linker_1_2 (352, 447)

RDFSILFYR
CRKAGLPVSKHYNVYKRPNCGQCRS--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICR
LPTRNTIISWTSGRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
TKQNQTLDEEFQNSPPTNVCLKD-TQHPSKKRTNN---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHSSSPDLK-SCNP-GY------------SSSERQINMTDGSRTFNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSVMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKMIPGC-

------------------------------------------------------------
------------------------VHGKKLFLRFHPHEEM--RTPG-----NNPLSE-PV
QKGAR--KAEAADKHSF----ASDGP-------HL---RSTELVPNGEDS-SCCC---GG
DATA-GAPEKWLHVS--FD-LVSSIQVNEFSRAKKANKRGNWKDPVPR-------LVL--
-NFDGGGFLTFYNCQMSW--S-----SFLVVKPNS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 371)

DILSEKFHRGQAVEAL--GQAQPVC
YILLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--LLSRPCLESLMDHVVEFSNNWLQ
GKFQDK--RQHTQIYQKKQCPVGHQTMMDMFGPPGGFRRLTWWCPQCQPRLPPEELEQLS
K-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 259)

PEGPSVRKFHHLV--SPFVGQEVVK
TGGSSKKLNPASFQSLW--LQDTQVHGKKLFLRFDPDEEF--GSLG-----NISLPE-SL
EKGER--KEEASDQKQAS---GPSSQKISH-SSSQ---SLELVAPRGDHG-LERL---CG
DTPA-EGAERWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPIPR-------LVL--
-YFGGGGFLAFYNCQMSW

ENSGT00730000110955_0_Linker_0_1 (259, 276)

S-------SSPVVRPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 363)

DILSEKFDRGQALEAL--GQEQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPQHLEALVDHAVEFSADWLQ
GKFQGK--QQHTQIYQKEQCPGGHRVMKEAFGPPGGFQRLTWWCPQCQPRLPPD------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRTRVLPGQAVTE
VRGTA-------LPSLQ-------------------------G-AA-----L-PLAA---
-SAAVVSS-QDSALND----NNYYIQNVSR--------QFHGYVYSGVET----L----G
KELFLYFGPKAVRIH--FG-MKGFIKINPLEYKNKN----G---VPPV-------FEVQL
T----KDLICFFDSSVELRNS-MESQQRIRMMEELDVCSPKFSFSRAE

PF06831 // ENSGT00730000110955_0_Domain_1 (289, 352)

TEIIKQKGRMLC
DVLLDQKVLPGVGNIIKNEALFDSGV--HPAVKVC--QLTDKQTHHLVKMV

ENSGT00730000110955_0_Linker_1_2 (352, 448)

RDFSILFYK
CLKTGLAISKHYKVYKRHNCGQCHC--KITVCRLGENNRMTYFCPHCQKENPQLI-DICK
LPTRNTVVGWKSSREDH-LMDSVAQKS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEQWVCVACTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-LFKNEE-NSVAF-NSLVKYPCNSFGKPHTELKINRKTAFGTTTLVLTDLSNKSSTLERT
KSPNQILDGEFQNLPSTNISLSE-AQYPSKERTNY---VAQPSNKV--KIAPTVFSQSKL
FSPAHKKLKTTHYSSLDLQ-SCKP-GF------------SNSELQINMTDGPCTLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHNRLCILRVVRKDGENKGRQFYACPLPGEAQCGFFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PLCNHGKRSIMRTV
LKIGPNNGRNFFVCPLGKEKQCDFFQWAENRPGN-------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVVD
VRGSA-------VPNLE-------------------------S-PA-----L-LQAA---
-SRVQISS-QAVALNS----NKDSRQNFLR--------LFNGCVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSIMINPLECKRKN----G---VSPV-------FEVQL
T----KDLICFFDSSVELRNS-MESQQKIRMMAELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 351)

ICSPKFSFSRAESEVKKQTGRMLC
DVLLDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDQQTHHLVKM

ENSGT00730000110955_0_Linker_1_2 (351, 447)

TRDFSIFFYR
CCKTGSGVFKHCKVYRRPNCGHCHC--KIIVCRFGENNRITYFCPQCQKENPQHV-DICK
LPTRNTVVSWTSSRRDH-LIGLVAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCSVCTLINKPSAKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NTIVF-SNLIKYPCNSFGNTHTEVKINRKTVFGTTTLVLTDFSNKSSTLERK
RSQNQVLDGEFQNSLPTNVCLS-DTQHPSKERTNY---ITQLSNKV--NISPLVCSQSEL
FSPVHKKLKTTRHSEPDLK-SCNP-GF------------SNSELQTNMTAGPCTLNNGGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNLRCVLRVVRKDGTNKGRQFYACPLPGETKCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGRRSIMRTV
LKIGPNNGKNFFVCPFEKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLHPAAFQSLW--LQDAQVHGKKLFLRFDPDEEM--EPLN-----SSPQP----
IQGMW--QKEAVDRELAL---GPSAQEPSA-GPSG---SGEPV-PSRSAE-TYNL---G-
KIPS-ADAQRWLEVR--FG-LFGSIWVNDFSRAKKANKKGDWRDPVPR-------LVL--
-HFSGGGFLVFYNCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 355)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--CLSSSSREALVDHVVEFSKDWLR
DKFQGK--ERHTQIYQKEQCPSGHQVMKETFGPPDGLQRLTWWCPQCQPQLSSKGPQNLP
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHRLV--SPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDTQVHGKKLFLRFDPDEAM--GPPG-----SSPPPE-PP
QKEAQ--NEGAADPMQVG---EPSGQKTPD-GSSQ---SAE-LGPQGEDD-SEYL---ER
DAPA-GDAGRWLCVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-HFGGGGFVAFYNCQMSW--S-----SSPVVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--VLSASRREVLVDHVVEFSTAWLQ
GKFEGK--PQHTQVYQKEQCPAGHQVMKEAFGPQNGLQRLTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTG
VRGRA-------LQSLV-------------------------G-PA-----L-PPAA---
-SQVEVSS-QAA-TVN----TKDCGWEFLR--------LFNGYVYSGVET----L----G
KELFMYFGPIALRIH--FG-MKGFISINPGECENRG----G---VSPT-------FQVQL
T----RDLICFFDSSVELRNS-TESQQRVRMMEELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSLSRAESEVKQQKDRMLC
DVVLDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--ELSEEQTHHLVKMIRDFSILFYR
CHKAGSAISKHYKVYKRPNCGQCHC--KITVCRLGENSRMTYFCPHCQKENPQHV-QLCK
LPTRKAVISWTSGREDC-LMDSVARKFEEQWSCVVCTLINKPSAEACDACLTVRPVDS--
-VLKNEE-NNIAA-SNLVKYPCNNFGNTHTEVKINRKAVFGSTTLVLTDFSNKSSTSARK
KSPNQIIGGGFQNFLPTDVCFS-DLQHPSKEGANY---ITQPSNRV--NISPTVCAQSKL
FSSAHKKLKTAHSSEADPK-YYNP-GL------------SNSERQTSTTDGPRSVNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCKKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PLCKHGKRSIMRTV
LKIGPNNGKNFFVCPLEKEKQCNFFQWAESGPGMEIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLHPATFQSLW--LQDAQVHGKKLFLQFDPDEEM--EPLS-----RSPQP----
VQGMW--QKEAGNPEPAL---GPSAQETSV-GPCG---SGEPG-PSTSDG-PYDL---RG
KKPL-AEAQRWLEVR--FG-LFGSIWVNDFSRAKKANKRGDWIDPVPR-------LVL--
-HFSGGGFLAFYNCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--FLSPSSLEALVDHVVEFSTDWLR
DKFQGK--ERHTQIYQKEQCPSGHQVMKETFGPPDGLQRLTWWCPQCQPQLSSEGPQNLL
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGTA-------LQSLL-------------------------G-PA-----T-SPAA---
-SPADVAT-SAA-PIN----AKDSGWKLLR--------LFNGYVYSGVET----L----G
KELFMYFGPRALRIH--FG-MKGSILINPREGENRG----G---ASPA-------LAVQL
T----RDLICFYDSSVELRNS-MESQQRVRVMEEL

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 351)

DVCSPKFSFSRAESEVKKQRDRMLC
DVLLDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLSDKQARHLVKM

ENSGT00730000110955_0_Linker_1_2 (351, 447)

TRDFSILFYR
CCKAGSAISKHYKVYKRPNCGQCHS--KITVCRFGENSRMTYFCPHCQKENPQHV-QVCQ
LPTRNAEISWTPRGENC-FTDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWSCAVCTLINRPSAKACDACLTTR

ENSGT00730000110955_0_Linker_2_3 (475, 660)

PLDS--
-VLKNRE-NSIAF-NNLVKYPCNNFENTHTEVKINRKTAFGNTTLVLTDLSNKSSALARK
KRVNHTIDGESQMFLPTDIGFS-DSQHPSKEGINY---ITQPSNKV--NISPTVCAQSKL
FSSAHKKFKPAHSSATELK-SFNS-GL------------SNSELQTNRTHGHHSKSDGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 704)

P
LCKMHHRHCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCRHGKRSIMKTV
LKIGPNNGKNFFVCPLEKGKQCNFFQWAENGPGMEIVPGC-

----------------------------------MPEGPLVRKFHHLV--TPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDAQVHGKKLFLRFDPDEEM--GPPG-----NSPPPE-PP
QKDMQ--KEEAADPRQAW---EPNGRKTPD-GSSW---SEE-LVP-------QCL---AG
AAPA-GGAGSWLRIC--FG-LFGSIWANEFSRAKKANKRGDWRDPAPR-------LVL--
-HFGGGGFLAFYNCQMSW--S-----SSPAVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 353)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQKYFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSASRREALVDGVVEFSAAWLQ
GKLQGH--PQHTQVYQKERCPAGHQLLKEAFGPPGGFQRLTWWCPQCQPQLSEE-LEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRKRVRPGQVVTG
MRGSA-------LLSLE-------------------------G-PA-----W-PRAA---
-SVAGVSL-QAAAMSN----K----KNSLS--------LLNGCVYSGVET----L----G
KELFLYFGTKALRIH--FG-VKGSILINPHLHKNNT----G---TAPV-------FEVQL
T----NDMICIFDSSVEVRNS-KESQHRVKTMEEL

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 351)

DVCSPKFSFSRAESEMKKQKGRMLC
DVLLDQKVLPGVGNIIKNEALFDSGF--HPAVKVC--QLSDEQTHYLVKMTRDFSILFYR
CHKSGSAISKHYKVYKRPNCGQCHC--KITVCRLGENNRMTYFCSHCQKENPQHV-DICT
LPIRNLLIHWTSSKEEL-LMDTMAQKSEEQWACVVCTLINKPSAKACEACLTSRPVDS--
-LLKNEE-DSVAF-NSLVKYPCNSFGKTHAEVKINRKTVFGNTTLLLTDFSNKSSNLERR
KSQNQILHGEFQNILSSNECLYD-TQHHSKERTNC---VMQQPNKV--NISPALCSPSEL
FSPAHKKLKIAYHSPTDPT-SYNS-GF------------TNSGLQINMADHPSSLNARVP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

HCSKHKRLCVLRVVKKDGENKGRQFYACPLPQEAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCSHGKRSIMRTV
LKIGPNNGRKFFVCPFEKEKQCNFFQWAENGPGINIIPEC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LPH----------------------------------------AA---
-RGAAASS-QAAE-LN----NKDCSWNFSG--------LLNGYVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSIVINPPHYKSKN----G---VSPV-------LEVQL
T----KDLICFFDSSIEFRSS-KESQQKIRMMEELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 353)

VCSPKFSFPRAESEVKKQKDRMLC
DVLMDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKVGSAVSKRYKVYKRPNCGQCHC--KITVCRFGENNRMTYFCPYCQKENPQHV-DICK
LPTRNTIVSWTSRGVNP-HTDCVAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLASR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDA--
-VLKNEE-NSIAF-NNLVKYPCNSFGKPHTEVKFNRKTAFGTTTLVLTDFSNKFSILEGK
KKPNQILDEAFQNSPSTNVCFS-DALHPSKEKTNY---ITQLPSKV--NISPTICSESKL
FSPAHKKLKTTHFSSPDFK-SCNP-GF------------SNSALQINTTDGSCTLNTGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCVLRVVWKDGENKGRRFHACSLPREARCGFFQWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGLKTIPGC-

------------------------------------------------------------
------------------------VHGKELFLRFDLDEET--GSPG-----NNPLPE-PL
EK-----KEEAGDQKQTF---GCDSQKISD-QPSR---SLNPVVPSGDNG-SECL---GG
DSPA-GGTERWLQVR--FG-LFGSVRANEFSRAKKPNKRGDWKDPIPR-------LVL--
-HFGGGGFLAFYNCQMSWH-------SSPVLRPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 355)

DILSEKFHRGRA-EAL--GQEQPVC
YTLLDQRYFSGLRNIIKNE-LYRAGI--HPLSLGS--LLSPPQLEILVDQVVEFSAHWLQ
GKMQGT--QQHTEIYQKEQCPAGHQVMKEAFGPPGGFQRLTWWCPQCQPRLPPDEPEQVQ
L----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRRFHHLV--SPFVGQQVVK
TGGSSKKLNPAGLQLLW--LQDAQVHGKKLFLRFDPDEEI--VCPR-----SSPLSE-PL
HDEEH--MEEARHHQEVS---DLPS-------QSA---GGAHVVPSGDDGPPQCV---GG
DSPA-GGAERWLQVS--FG-LFGSVWVNEFSRAKKANKKGDWKDPIPR-------LVL--
-HFGGGGFLAFYNCQMAWS-C-----SSPVVSPAS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DILSEKFHRGQALEAL--GRDQPVC
YTLLDQRYFSGLGNIIKNEALFRAGI--HPLTPGS--LLGALRLEALVDHVVAFSAGWLE
GKFQGR--QQHTQIYQKDRCPAGHQVVKEALGPPGGLQRLTWWCPQCQPRLPAAGPEQVQ
P----------------------------------------P------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPLVRKFHHLV--SPFVGQQVVK
TGGSSKKLQPASLQCLW--LQDTQVNGKKLFLRFDPDEEM--GPPG-----SSPPPE-PP
QKEAQ--KEGAADPKQVG---EPSGQKTPD-GSSQ---SAE-LVPQGEDD-SEYL---ER
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKQANKRGDWRDPSPR-------LVL--
-HFGGGGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 293)

CQMSW--S-----SSPVVTPTCDILSEKFHRGQALEAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 356)

-GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--VLSASRREVLVDHVVEFSTAWLQ
GKFQGR--PQRTQVYQREQCPAGHQVMKEAFGPQDGLQRLTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 255)

PEGPSVRKFQLLA--SRFVGQVVAK
VGGSTRKINVDDLKSLR--LQGAQVHGKNLFLAFVAAGC--------PLGPNTDN---PV
LQGEA--ASGTSS----------PAQVCAAWTHPEEEELQE-LLCS-------RP---DV
P----GGPGSWLRVH--FG-LFGSIRANEFSRASQANKRGDWKDPTPR-------LVL--
-HFESGGFLVFYNC

ENSGT00730000110955_0_Linker_0_1 (255, 276)

RMQW--C-----SSPVADPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 369)

DILSADFHRGQALDAL--RAPRPVC
YTLLDQRYFSGLGNIIKNEILYLAKI--HPLTQGS--LLVSSDLEHLLDCAIQFSLDWLQ
SKLRDE--GLHFQIYQKEQCPLGHAVMKGTFGPSGGYKRLTWWCPQCQPAVLSGVLSGGD
R-R-----RFC-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHRLV--SPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDTQVHGKKLFLRFDLDEEM--GPPG-----SSPTPE-PP
QKEVQ--KEGAADPKQVG---EPSGQKTLD-GSSQ---SAE-LVPQGEDD-SEYL---ER
DAPA-GDAGRWLRVS--FG-LFGSIWVNDFSRAKKANKRGDWRDPSPR-------LVL--
-HFSGGGFLAFYNCQLSW--S-----SSPVVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--VLSASRREVLVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEE-PEQCQ
F-S-----EGAGGAPHG-------------------TLP-LGEPDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--STFVGQQVLK
TGGSSKKLCPATLQSLW--LQDTQVHGKKLFLRFDADAEG--EGEGGAPGGSHQHLE-PL
RKTAR--KEAAGDPAPEA---S--GQKTAADGSFQ---SME-LLPRGPGD-SSDL---AG
DSPL-PGAQQWLQVS--FG-LFGSIWANEFSRAKKANKRGDWRDPVPR-------LVL--
-YFDGGGFLAFYNCQMSWS-------PTPVVEPHRDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEEFHRGQALEAL--GQPQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--LLTSPCLETLVDHVVAFSAEWLQ
GKFQGQ--PRHTQVYQKEQCPSGHQVLREVLGPPGGLQRLTWWCPQCQPRVPPEETPQHQ
S-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSIMINPLECKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRVGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPRCQKENPQHV-DICR
LPTRNTIISWTSSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-MLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
KKQNQTLDKEFQNSPPTNVCLKD-TQHPSKKRTNN---ITQLSSKV--NIAPTISSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSELQINVTDGPRTLNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVMG
VRGSA-------VQSLA-------------------------G-PA-----A-PPAA---
-LAAEASA-QDTPLHN----NNDPSRNFLR--------LFDGCVYSGVET----L----G
KELFMYFGPKALXXX--XX-XXXXXXXXXXXXXXXX----X---XXXX-------XXXXX
X----XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXVC--QLTDEQIHHLVKMTRDFSTLFYK
CCKVGSAISKHYKVYKRPNCGRCSR--KITICRLGENNRMTYFCPHCQKENPQHA-NIRQ
LPPGTSIISGTFKRRDQFQEDCVAR

PF00641 // ENSGT00730000110955_0_Domain_2 (446, 476)

RSEEHWTCVACTLINTPSSRTCDACLTCRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

IDS--
-ILKNEE-NSVPF-TSLVKYPSNNFGKPNTEVKINRRTAFGTTTLVLTDFSNKSNTLERK
QSQNNRLDVEFQSSCIN-AGLC-DLPLTSKKRTSS---RIQPSNKV--NASPTVCSQSKS
LTPAYKRLKTTHDSSPDLP-SPYP-GH------------SERELQASMTDGPCTLNAGT

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRVVRKDGENRGRQFYACPLLGELQCGFF-WADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGKKFFVCPLGKEKQCNFFQWAENGPGIKILPGC-

------------------------------------------------------------
------------------------------------------------------------
----------AAAMKD----SND-------------------------------------
---------SSQKIH--FG-MKGSIMINLLPCKNKN----G---DSSV-------FELQL
T----NDLICFFDSSVELRNS-VEIQQRIRMMRELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSFLGAESEVKKQRDRMLC
DVLLDQKVLPGVGNIIKNEALFDSGL--HPALKVF--QLTDEQIHHLVKMVR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKTGSAISKHYKVYKRPNCGQCHC--KITVCRLGENNRMTYFCPHCQKENPQHT-DICK
LPTRNTIINWRSSSGNH-LTDSVGRK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCLVCTLINKPSAETCDACFTSK

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-VFKNEE-NSIVF-HNLVKYPCNTFRKAHAEVKINRKTAFGTTTLVLTDFSNKSNTLKRK
ESQTQTPDGEFQNSLPTNICFSD-TRHPSKERTNY---ITQVSNKV--NTSPTVCSQSEL
FSSAHKKLKTTHYSTPDLK-SCNT-GF------------SNSQLRASMTDGPCTSNAGGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCRKHNRLCVLRVVRKRGENRGRQFYACPLPGDAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCSHGKRSIMRTV
LKIGPNNGRNFFVCPLEKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGTA-------LQSLL-------------------------G-PA-----M-SPAA---
-SLADVAT-SAA-PMN----AKDSGWKLLR--------LFNGYVYSGVET----L----G
KELFMYFGPRALRIH--FG-MKGSILINPREGENRA----G---ASPA-------LAVQL
T----RDLICFYDSSVELRNS-VESQQRVRVMEELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 349)

ICSPKFSFSRAESEVKKQGDRMLC
DVLLDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLSDKQACHLV

ENSGT00730000110955_0_Linker_1_2 (349, 447)

KMTRDFSILFYR
CCKAGSAISKHCKVYKRPNCDQCHS--KITVCRFGENSRMTYFCPHCQKENPQCV-QVCQ
LPTRNTEISWTPRGEDC-FTDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWSCVVCTLINRPSAKACDACLTTR

ENSGT00730000110955_0_Linker_2_3 (475, 660)

PLDS--
-VLKNRE-NSIAF-NNLVKYPCNNFENTHTEVKINRKTAFGNTTLVLTDLSNKSSALARK
KRANHTIDGESQMFLPTDIGFS-DSQHPSKEGINY---ITQPSNKV--NISPTVCAQSKL
FSSAHKKFKPAHTSATELK-SYNS-GL------------SNSELQTNRTRGHHSKSDGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 704)

P
LCKMHHRRCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCRHGKRSIMKTV
LKIGPNNGKNFFVCPLEKKKQCNFFQWAENGPGMEIVPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STTVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSVMINPLECKYKN----G---AFPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRVGMMKELDVCSPE

PF06831 // ENSGT00730000110955_0_Domain_1 (282, 353)

FSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 448)

DFSILFYR
CHKAGLAVSKHYKVYKRSNCGQCRC--RITVCRFGDHNRMTYFCPRCQKENPQHV-DIRR
LPTRNTIISWTSSRMDH-VLDSVARKS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
-KQNQTLDKEFQNSPPTNVCLKD-TQHPSKKSTNN---ITQLSSKV--NISPTISSASKL
FSPAHKKLKTAHCSSPDLK-SCNP-VY------------SSSELQINVTDGPHTLNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHSRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKMIPGC-

----------------------------------MPEGPSVRKFHHLV--STFVGQQVLK
TGGSSKKLCPATLQSLW--LQDTQVHGKKLFLRFDADAEG--EGEGGAPGGT--------
-----------GDPAPEA---S--GQKTAADGSFQ---SME-LLPRGPGD-SSDL---AG
DSPA-PGAQRWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPVPR-------LVL--
-YFDGGGFLAFYNCQMSWS-------PTPVIEPHRDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEEFHRGQALEAL--GQPQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--LLTSPCLETLVDHVVAFSAEWLQ
GKFQGQ--PRHTQVYQKEQCPSGHQVLREVLGPPGGLQRLTWWCPQCQPRVPPEETPQHQ
S-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTS
VRGSA-------LRSLQ-------------------------G-RA-----L-RLAA---
-STAVVSP-QVSYSCN----R-PCSQQGGN----------GIKTPSGFQD----L----K
CHLFVSWGPTFHRVYRHFTVGRSFIMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQQRIRMMKELDV

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 353)

CSSEFSFLRAESEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQIHHLMKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLALSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNTIISWTSSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEHWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKSEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERK
TKQNQILDEEFQNSTPTNVCLND-IQHPSKKTTND---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHYSSAELK-SCNP-GY------------SNSELQINITDGPHTLNPDSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRNLR-------------------------G-RA-----L-RRAA---
-SSAVVSP-QAAVLNN----N-DSSQNVLS--------LFNGYVYNGVET----L----G
KELFMYFGPKALRIH--FG-MKGSVMINPLEYKYKN----G---TSPV-------LEMQL
T----KDLICFFDSSVELRNS-MESQQRIRMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPTFSFLRAESEVKKQKGQMLG
DVLMDQSVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDGQIHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHCKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNSVISWTPSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-V-KNEE-NSAAF-SNLVKYPCNTFGKPHAEVKINRKTTFGATTLVLTDFSNKCSSLERK
TKQNQTLDEEFQISPPNNVCLSD-TQHPSKKRTNA---ITQLSSKA--NVSPTISSESKL
FSPTHKKLKIAHYSSPDLK-SCNP-GY------------SNSELQINVTDGPRTLNPGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNHLCILRVVRKDGENKGRHFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
MRGSA-------LRSLQ-------------------------G-RA-----L-RLAA---
-STAVVSP-QAAALNN----N-DSGQNVLS--------LFNGYVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSIMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-VESQQRIRMMKELDV

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 353)

CSPEFSFLRAESELKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVF--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLALSKHYKVYKRPNCGQCHC--RVTVCRFGDNNRMTYFCPHCQKENPQHV-DVCN
LPPRNTIISWTSSKVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-ALKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERK
TKQNQILDEEFQNSPPTNVCLND-TQHPSKKRTNN---ITQLSSKV--NISPTISSESQL
FSPAHKKLKTAHYSSPELK-SCNP-TY------------SNSELQINVTDGPRTLNPDSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNHLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPRIKIIPGC-

------------------------------------------------------------
------------------------------------------------------------
------------AASE----ER---TSSHD-------

PF01149 // ENSGT00730000110955_0_Domain_0 (158, 210)

-FLSGQVFRGVET----L----G
KEFFMYFDQKALRIH--FG-MNGSMRINP

ENSGT00730000110955_0_Linker_0_1 (210, 275)

DRSKDRN----G---ALPV-------LEIQL
I----EDTICFFEVTAEYRNV-AECEQKVRMMES

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 360)

LDVCSPKFSFLRAESEVKQQKTQMLC
DVLLDQTVLPGVGNIIKNEALFDSGL--HPAAKVC--QLTDEHIRHLVKMTRDFTLLFY

ENSGT00730000110955_0_Linker_1_2 (360, 447)

K
CRKTGSPLYKHYKVYRRQTCGQCNE--KITVCRLGENNRMTYFCSRCQKADPQLV-SVSK
LPTRNSLIGWACGRGSC-SNEHIAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEEWTCMRCTLINKPSAEACDACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

EVSSS
LKTEKVE-DSTDFNINLIKYPCNDFRKPSREIKINRKAAFGTTTLVLTDLGNKAVL----
KDDIQLSDGCSEYVAPKGNLSQNQNNVYHSGTGIDKYCSTNVTS-----VASSSCQDASL
FKPEKKKQKTHHVSS-VHQHNVMI-GK------------ENSKPQVNSADDIHTLSTGP

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
HCSKHGHLCKLRIVRKDGENKGRMFYSCPLPSETQCNYFQWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

NF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCHHGKRCVMKMV
LKLGPNNGRNFFVCPLRKEKQCGFFQWAENKPVTQSTP---

----------------------------------MVEGPGCTLNGEKIRAKVGRGQAVTA
VRGSA-------LQSLE-------------------------S-RA-----L-PHAA---
-SVAVTSS-QXXXXXX----XXXXXXXXXX--------XXX----XXXXX----X----X
XXXXXXXXXXXXXXXIHFG-MKGSIMINPLERKNKN----G---VSSV-------FELQL
T----KDLICFFDSSIELRNS-MESQQRIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 348)

LDVCSPKFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSSL--HPAVKXX--XXXXXXXXXXXXXXXXXXXXXXX
CRKSGSAISKHYKVYKRSNCGQCHC--KITVCRLGENSRMTYFCPHCQKENPQHVN-IXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXS--
-TPQNEE-N--LS-PPFLMCPCNNFG-PHTEMKINRK-AFGTTTLVLTDFSNKSSTVERK
KSPNQILDEEFQNSPPTNICFSDNTQHPSEERTNY---IAQLSNKV--NISPAVCSQSKV
FGPTHKKFKTTHYSSPDLK-RYNP-GF------------SNSELQINMTDDPSTFNAGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRVVRKDGENKGRQFYACPLPKEAQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHHLV--SSFVGQQVVK
TGGSSKKLHPDGFQALW--LQDAQV-----------------------------------
------------------------------------------------------------
-----------------------------------------------R-------LIL--
-HFGGGGFLVFYNCQMSWS-------SSPVVTPTCD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 354)

ILSEKFHRGQALEAL--GQAQPVC
YTLLDQRHFSGLGNIIKNEALYKAGI--HPLALGS--LLSPSRLEALVDHVVEFSTDWLQ
GKLQGK--QKHTQIYQKEHCPAGHQVMKKALGPPSGFQRLTWWCPHCQPQLSSEGPEQSQ
L----------------------------------------SE-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTRNGEKIRARVRPGQAVTD
VRGRA-------LQGLG-------------------------G-PG------SPPAA---
-SRPAGPS-QAAALTN----NQNSSQDFLR--------LFNGHVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSLIINPVESKNKN----G---VSPD-------FEVQL
T----KDLICFFDSSVEIRNS-TESQQRIRVMEELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 353)

VCSPRFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPSVKVC--QLTDEQIHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKVGSALSQHYKVYKRPNCGQCCC--KITVCRLGENNRMTYFCPHCQKENPQHV-DICM
LPVRNTTVSWPSSREGH-LIDCVAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCEVCTLINKPSSKTCDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PADS--
-VFRNEG-NPAVF-NNLVKYPCNSFGKPKAKVKINRKTAFGTTTLVLTDFSNKYSALERE
ESHNHIPDGEFPSP-PPNMCGSD-TLNTSKERTNY---RSQPSNKI--NISPIVYSQYKL
FSPAHKKLKTTYYSSPDLK-SCNP-GF------------SNSELQSNMTDGPRLLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHGRPCALRVVRKSGENKGRHFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 710)

LSFPFY

PF06839 // ENSGT00730000110955_0_Domain_4 (710, 750)

NHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAQNGPGINIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLPPATLQSLW--FQDAQVHGKKLFLQFDPDEEM--ALPG-----SNPLAE-LV
GEGKL--EKEAMGPEPTL---GPSTQEPSA-G-SQ---CVELV--SGD---SSGQ---RG
HSPA-AGAQRWLEIR--FG-LFGSIWVNNFSRAKKANKRGDWSDPVPR-------LVL--
-YFGGGDFLAFYNCQMSWS-------PPPMVEPTCD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 354)

ILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--LLSSSHLETLVDQVVKFSTDWLQ
GKFQGK--GWHKQIYQKEQCPAGHQVMKEALGPTGGFQRLTWWCPECQPRLPQEEPQKLQ
N----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCALNAEKIRARVRPGQAVTG
VRGSA-------LXXXX-------------------------X-XX-----X-XXXX---
-XXXXXXXXXXXXXXX--------XXXXXX--------XXXXXXXXXXXX----X----X
XXXXXXXXXXXXXIH--FG-MNGAVQINPLKSKYQT----R---APSV-------FEVQL
T----KDLICFYDSSVEFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXVS--QLKDEQTCHLVKMIRDFTILFYR
CCKTGSALYRHYKVYKRSDCGQCRS--KITVCRLGENNRMTYFCPRCQKENPQSI-DIXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXINKPSVKHCDACMTSRPNSR--
-CKS--RGNSVAYDNNLMKYPCNSFVRHHPEVKINRKTAFGMTTLVLTDLSNNSSSLENI
RNQNTKPSGDFQNSSVGNICFS-DVHHPSKEKGKY---MALPSGKV--S---GFDSQSSL
LSPVYKKLKTNH-SFPELN-CCSP-GF------------SRIELQVNMTDSTCTKNING

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRVVRKDGESKGRQFYACPLPRESQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 752)

PFCNHGKRSIMRTV
LKVGPNNGRNFFVCPLRKEKQCDFFQWAP-GLGIEIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDTQVHGKKLFLRFDPDEEM--EAPG-----SSPLPE-PP
QKEAQ--KEGAADPKQAG---EPSGQKTPD-GSSQ---SAE-LNPQGEDA-SECL---EG
DAPA-GDAGKWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 294)

CQMSW--S-----SSPVVTPACDILSEQFHRGRALEAV--

PF06831 // ENSGT00730000110955_0_Domain_1 (294, 356)

GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHPVMKEAFGPPGGFQRLTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-RLAA---
-STAVVSP-QAAALNN----N-DSSQNVLS--------LFNGCVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGFIMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQQRIRMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAESEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQIHHLMKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLALSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNTIISWTSSRVDH-VMDSVAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEHWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKSEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERK
TKQNQILDEEFQNSPPTDVCLND-IQHPSKKTTND---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHYSSPELK-SCNP-GY------------SNS--------GPCTLNPDSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILQVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 255)

PEGPSLRKFHQLV--APFVGQLVVT
VGGNSKKINPNMLEMLR--LQDSQVHGKNLYLNFGLTEDL--GLPE-----SFLLPK-HL
QKKVR--LPKEKSDHKLETTSRLDGQEVPG-SSLA---IK--ALELGEEE-KETV-MPWW
LNTS-QNSGLWLCFH--FG-LFGSVRASELSRATKANKRGDWKDPIPR-------LVL--
-HFAK-GFLAFYNC

ENSGT00730000110955_0_Linker_0_1 (255, 276)

RIYW--C-----LGPTVKPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 352)

DILSEEFDRRQALEAL--KQASPVS
YTLLDQRYFAGLGNIIKNEVLYLARI--HPLSLGS--CLTPLNLESLLDHVVSFSVGWLQ
KKLEGK--PLHHLIYQKEQCPAGHQVMKDSFGPPGSFQRLTWWCPHCQPKAEEKVEVTQE
Q-L---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SAFMGQQVVR
TGGSSKKLCPASLQSLW--LQDTQVHGKKLFLRFDADVDT--DEEVGAPG-SSPRPE-PL
QKRAR--REATVGPAPE-----PNAQNTCD-GSSL---SAG-LLPRGPGG-PDGL---VG
DSLT-AGAPRWLQVH--FG-LFGSVWVNDFSRAKKPNKRGDWRDPMPR-------LVL--
-HFGGGGFLAFYSCQMSWS-------LAPAIEPCRD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 354)

ILSEEFHRGQALEAL--GRPQPVC
YTLLDQRYFSGLGNIIKNEALYKARI--HPLSLGS--LLSASCLETLVEHVVEFSTDWLR
GKFQGQ--QRRTQVYQKEQCPAGHQVLKEAFGPPGGLQRLTWWCPQCQPRLPPEEPQQLQ
S-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MRGSALLQIGASSSSSNGAC--QLTDEQVHHLVKMTRDFTLLFYK
CRKTGSALYKHYKVYKRPNCGQCGA--KITVCRLGENNRMTYFCPQCQKDNPQRV-DPSK
LPGRNSLIGWAYGRGSC-SKEQVAQKSEEEWSCMLCTLIIKPSVKICDACLTPRPEVP--
-RWQNNE-DLSGFNSDLVKYPCNNFEKPRTEIKINRKTAFGITTLVLTDFASISTQPRPN
GSENLTSDGSCLRGSSQND-YNTTFHFGVNKPGTFPYQAIEVIS-----IKINFIKLICC
LQDLLWSFQSRHLST-KERESYFP-GD------------ANRTPPDNMTDGSCPLSAAS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 703)

P
RCNKHSRFCVLRVVRKDGENKGRQFYACPLPKEARCDYFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLHF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRCIMRTV
LKIGPNNGKNFFVCPLGKDKQCDFFQWAENGPAMKIIPGC-

----------------------------------MVEGPGCTVNGEKIRARVLPGQAVTD
VRGRA-------LQSPQ-------------------------G-PG-----S-SLAA---
-PVAEVSF-QAAAMKD----SNDSSQNFLR--------LLNGYLYSGVET----L----G
KELFMFFGPKALRIH--FG-MKGSIMINLLPCKNKN----G---DSSV-------FELQL
T----NDLICFFDSSVELRNS-VEIQQRIRMMRELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSFLGAESEVKKQRDRMLC
DVLLDQKVLPGVGNIIKNEALFDSGL--HPALKVF--QLTDEQIHHLVKMVR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKTGSAISKHYKVYKRPNCGQCHC--KITVCRLGENNRMTYFCPHCQKENPQHT-DICK
LPTRNTIINWRPSSGDH-LTDSVGRK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCLVCTLINKPSAETCDACFTSK

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-VFKNEE-NSIVF-HNLVKYPCNTFRKAHAEVKINRKTAFGTTTLVLTDFSNKSNTLKRK
ESQTQTPDGEFQNSLPANVCFSD-TRHPSKERTNY---ITQVSNKV--NTSPTVCSQSEL
FSSAHKKLKTTHYSTPDLK-SCNT-GF------------SNSQLQASMTDGPCTSNAGGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCRKHNRLCVLRVVRKHGENRGRQFYACPLPGDAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCSHGKRSIMRTV
LKIGPNNGRNFFVCPLEKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHHLI--SPFVGQQVVK
TEGSSKKLQPAGLQSLW--LQDSQVHGKKLFLRFDPDEEM--EPPG-----SSPPPE-PP
QKEAH--KEGAADPKRDG---EPSGQKTLD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKDQCPAGHQVMKEAFGPPGGFQRLTWWCPQCQPQLPEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------LVL--
-HFGGGGFLAFYNCQMSW--S-----CSPVVRPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 363)

DILSEKFHRGQALKAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRARV--HPLSLGS--LLSPTHLEALVDHVVEFSTNWLQ
DKLQGK--QQHTQIYQKEQCPAGHPVMKDEFGPPGGFQRLTWWCPQCQPQFPPEGPHQPQ
L-C---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHHLV--SPFVGQQVVK
TGGSSRKLQPAGLQSLW--LQDAQVHGKRLFLRFDPDEEM--GPLG-----NSPPPE-PP
QKDTQ--KEGAADPRQAR---EPSGWKTPD-GSSQ---SAG-LVPQGEGD-SQCL---AG
AIPA-EGAGRWLRVC--FG-LFGSIWVNEFSRAKKANKRGDWRDPAPR-------LVL--
-HFGGGGFLAFYNCQMSW--S-----SSPAVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 353)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQKHFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSASRREALVDGVVEFSAAWLQ
GKLQGH--PQHTQVYQKERCPAGHQLLKEAFGPPGGFQRLTWWCPQCQPQLSEE-LEQRQ
V-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSVMINPLECKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRVGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIRDFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPRCQKENPQHV-DICR
LPTRNTIISWPSSRVDH-VMDSVARKSEEQWACVVCTLINKPSSKACDACLTSRPIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
KKQNQTLDKEFQNSPPTNICLKD-TQHPSKKRTNN---ITQLSSKV--NVSPTIRSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSELQINVTDGPGTLNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDKEM--EAPG-----SSPPPE-PP
QKEAQ--KEGAADPKQAG---EPSGQKTPD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPPGGFQRVTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHRLA--SAFVGQQVLK
TGGSSKKLCPATLQSLW--LQDAQVHGKKLFLRFDAVVGADADEEAGAPG-SSQPPE-PL
QKRAR--REAAVDPAPE-----PSEQKTGD-GSSR---SSE-LLPRGP----GGL---VG
DSPT-AGAQRWLQVH--FG-LFGSVWVNEFSRAKNANKRGDWRDPVPR-------LVL--
-HFGSGGFLAFYNCQMSWS-------PAPAIEPRCDIL

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 354)

SEEFHRGQALEAL--GQPQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--LLSPSCLETLVDHVVEFSADWLR
GKIQGQ--RQHTQENRI-----------------------FFL---CSPRDPGKRKKQQD
K-R-----TGSASCLAL-------------------SLG-MEMPGRPATFLEC-PLAF--
-------------REKLFV-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCALNGEKIRAKVRPGQAVLD
VRGSA-------LQSLG-------------------------G-PA-----L-PRAA---
-SLAVVSS-QAAALND----NK

PF01149 // ENSGT00730000110955_0_Domain_0 (143, 248)

DSSQNFSR--------LLNGCVYCGVQT----L----G
KELLMYFGPKALRIH--FG-MKGSIMINPLENKNKN----G---VSPV-------LEIQL
T----KD

ENSGT00730000110955_0_Linker_0_1 (248, 281)

LICFFDSSVEFRNS-AESQQRVRMMEELDVCSP

PF06831 // ENSGT00730000110955_0_Domain_1 (281, 353)

KFSFSRAESEVKKQKGRMLC
DVLMDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHYLVKMIRDFSILFYR
CRKTGSVISKHYKVYKRPNCCQCCC--KITVCRLGENNRMTYFCPRCQKENPQQV-DICS
LPRRDTTIRWPSSRGDH-----VARKSEEQWACVVCTLLNRPSSKTCDACLTSRPTDL--
-AIKNED-NSIDF-TNLVKYPCNSFGKPSTEVKINRKTAFGTTTLVMVDFSNKSSGLERK
TSQNQILDGEFQNPPRTNVCSSDDPLHPSKERTNR---TPQPSDKV--NVSPAVCAQSKL
FSPAYKKLKTTHPSSLDLK-SAHP-GF------------SNSEPGINMTDGACVLNADSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHNRLCALRIVRKDGDNKGRRFYACSLPREAQCGFFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PLCDHGKRSVMRTV
LKIGPNNGKNFFVCPLEKAKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLHPASLQSLW--LQDTQVHGKKLFLRFDPDEET--GPPG-----DGPSLE-PP
QKGAW--KEGAADPKPK---------APEG--PSG---PEQPVVPCGEDA-PGRL---GA
DLPA-EGAERWLQVS--FG-LFGSVWVNEFSRAKKANKRGDWKDPSPR-------LVL--
-HFGGGGFLAFYNCQMSWG-------SSPVVQPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--ALSPSSLEALVDCVVQFSTDWLR
DKFQGR--QQHTQIYQKEQCPAGHRVTKEALGPPGGFQRFTWWCPQCQPRSPPEGPEQCL
P-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTS
VRGSA-------LRSLQ-------------------------G-RA-----L-PPAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSVMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRIGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLLDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHYKVYKRPNCSQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICR
LPTRNTMISWTSGRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVLCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFRKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
KKQNQTLDEEFQNSPPTNVCLKD-TQNPSKKRTNN---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSERQINMTD--------GP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

MGRRAGKSPPPAVAAVRAAQRCWVGPTCHPHGAGMPEGPLVRKFHRLV--SPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDTQVHGKKLFLRFDLDEEM--GPPG-----SSPTPE-PP
QKEVQ--KEGAADPKQVG---EPSGQKTLD-GSSQ---SAE-LIPQGEDD-SEYL---ER
DAPA-GDAGRWLRVS--FG-LFGSIWVNDFSRAKKANKRGDWRDPSPR-------LVL--
-HFSGGGFLAFYNCQLSW--S-----SSPVVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--VLSASRREVLVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEE-PEQCQ
F-S-----EGAGGAPHG-------------------TLP-LGEPDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 244)

PEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLNPAGFQSLW--LQDTQVHGKKLFVRFDPDEEI--VSPG-----NNPLSE-PL
QKEWK---EEAGDHQEVS---EQSSRFP--------------GVPSGGDG-LRCL---WG
DTPA-GGAERWLQVS--FG-LFGSVWGNEFSRAKKANKRGDWRDPVPR-------LVL--
-HF

ENSGT00730000110955_0_Linker_0_1 (244, 276)

GGGGFL-FYNCRVGG--S-----SSRVVRPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 355)

DILSEKFHRGQALEAL--CREQPVC
YTLLDQRYFSGLGNIIKNEVLFKAGI--HPLSPGS--LLGLPRLEALVDHVVAFSAGWLR
GKFQGR--QQHTQIYQKEWCPAGHQVVKEALGPPGGFQRLTWWCPQCQPRLSLDEPEQVP
P----------------------------------------SS-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRTRVLRGQAVTD
VRGKA-------LQSLE-------------------------G-LL-----S-SHTA---
-SVAEVSF-QAAAPKE----GKDSTQNFLR--------LFNGYVYSGVET----L----G
KELFMFFGPKALRIH--FG-MKGSIMINPLAYKNKN----G---VSPV-------FELQL
T----NDLICH-------RNS-MESQQRIRMMEELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 352)

VCSPKFSFLRAENEIKKQKGRMLC
DVLLDQKVLPGVGNIIKNEALFDSGL--HPAVKIF--QLTDEQTHHLVKMVRDFSILFYR
CCRTGSAISKHCKVYKRPNCGQCQG--KIIICRLGENNRMTYFCPHCQKQNPQHT-DVCK
LPTRNTAINWTCSRGDH-LTDSVGWKSEEQWTCLVCALVNKPSAETCDACLTSKPVDS--
-MLETEE-NSIVF-HNLVKYPCNSFGKAHTEVKINRKTVFGTTTLVLTDFSNKSNTLKRK
ESQIQTPDGEFQNSLPTNVCFSD-TRHPSKERTNC---ITQVSNKV--NISRTVCSQSEL
FSSVHKKLKTSLYSTPDLK-SCNT-GF------------SNSEPQVSVAGGPCALNVGRP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCVLRVVRKDGENKGRHFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCSFEKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQQV-K
TGGSSKKLNPADLQSCAPGHQDVQVHGKKLFLRFHPDEEV--RPPG-----NNPLSE-PL
QKGAR--KEVATDQKQTL---GPDGPKISD-QSLR---STE-LAPNGEDS-SHCS---GG
SAPA-GDVERWLHVS--FG-LFGSIWANEFSRAKKANKRGDWRDPVPR-------LVL--
-NFGGGGFLAFYNCQMSW--S-----SSSVVTPNS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 369)

DILSEKFHRGQALEAL--GQAQPVC
YILLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--LLSPSSLESLVDHVVEFSTNWLQ
DKFQDK--RQHTQIYQKEQCPVGHQIMKDMFGPPGGFQRLTWWCPQCQPRLPPKEPEQLQ
L-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLHPPDLQSLW--LQDTQVHGKKLFLRFDPDEEL--RLRG-----NDPLPE-PL
RKGAQ--EVEAADQEQAV---GPSRQTASD-KSSQ---AAALAVPPGDEG-PKCL---GA
DCLT-PGAERWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPAPR-------LVL--
-YFGGGGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 293)

CQMSW--S-----SSPVVRPTSDILSEKFHRGQALEAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 355)

-GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGV--HPLSLGS--LLSPSCLEALVDHVVEFSTHWLQ
DKLQGR--QQHPQIYQKEQCPAGHQVLKQELGPPGGFQRLTWWCPQCQPRLPAEGPEQHQ
R-A---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 255)

PEGPTVRRFCSLV--SPFVGQNVVK
VGGSTKKIALQDLQGKQ--FHYCQVHGKNLYLEFTTKAVGN--ILSG----TEDAKE---
----H--IDQAGGSQKD----------YSIIQPTSEEHSE-------------SL---QD
ADYSEIHMSRWLRFH--FG-LYGSVRSNEFARAKQANKRGDWRDPTPR-------LILNF
---ESGGFLVFYNC

ENSGT00730000110955_0_Linker_0_1 (255, 276)

RMAW--C-----SSPASKPNC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 356)

DVLSPEFDTEQAVRAL--SASQPVC
FTLMDQKCFSGVGNIIKNEILFLEQV--HPLCLGS--LLPIEKLHSLVSHTLHFTSDWLS
SKMKKE--ALHYHIYMKEYCDKGHKVIKEKLGPPYGIKRLTYFCPVCQPQVKCDPSSSSL
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LPSLE-------------------------G-RA-----L-PHAA---
-ASS-----Q-AAALN----K-DANQNFLK--------LFDGYVYSGVET----L----G
KELFMYFGQKAFRIH--FG-MKGSVMINPLGYENRN----G---VSPV-------LEIQL
T----KDLICFFDSSVELRNS-MESQQRIRMMEELD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 353)

ICSPKFSFSRAESEVKKQRGRMLC
DVLMDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIRDFSILFYR
CRKAGSAISKHYKVYKRPNCGQCHC--KITVCRFGENNRMTYFCPHCQKENPRHV-DICK
LPTRNTIISWTSSRVDH-LMDTVARKSEEQWTCGVCTLINKPSSKSCDACLTARPVDS--
-MLKNEE-NPIAF-NNLVKYPCNSFGKPDTEVKINRKTAFGTTTLVLTDFSNKSSTLERK
KSQNQILDGEFPNPPPPHVCFSD-TQHPSKERTNY---ITQLSSKV--NTSPTVCSESKL
FSPAHKKLKTTHYSSPDLK-SCNP-GF------------SKSELQINMADGPCAFNTGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCTFRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCSHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCSFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSVMINPLECKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRVGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIRDFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPRCQKENPQHV-DVCR
LPTRNTIISWTSSRVDH-VMDSVARKSEEQWACVVCTLINKPSSKACDACLTSRPIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
KKQNQTLDKEFQNSPPTNVCLKD-TQHPSKKRTNN---ITQLSSKV--NVSPTISSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSELQINVTDGPGALNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKSFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRNLQ-------------------------G-RA-----L-PLAA---
-SSAVVSP-QAAILNN----N-DSSQNVLS--------LFNGYVYNGVET----L----G
KELFMYFGPKALRIH--FG-MKGSVMINPLEYKYKN----G---TSPV-------LEMQL
T----KDLICFFDSSVELRNS-MESQQRIRMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPTFSFLRAESEVKKQKGRMLG
DVLMDQSVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDGQIHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHCKVYKRPNCGQCHC--RITVCRFRDNNRMTYFCPHCQKENPQHV-DICK
LPTRNSVISWTPSRVDH-IMDSVAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VVKNEE-NSTAF-SNLVKYPCNTFGKPHTEVKINRKTTFGTTTLVLTDFSNKSSTLERK
TKQNQILDEEFQIFPPPTVCLSD-TQHPSKKRTND---ITQLSSKA--NVSPTISSESKL
FSPTHKKLKTAHYSSPDLK-SYNP-GY------------SNSELQITMTDGPRTLYPGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCNKHNRLCILRVVRKDGENKGRHFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 253)

PEGPSVKRFQLLT--APFVGQVVAK
VGGSSRQSSLQDLKAMR--LQDSQVSGKNLFLAFCAALEA--QPMKGSPSPVEEG---PT
PQGKA--DSGACSLRQ-----AREREVDDVSLRSSEEHS-V-QRKQ-------EP---EG
S-EAPGDAWKWLRFH--FG-LFGSIRANEFARANKANKRGDWKDPVPR-------LVL--
-HFDTTGFLVFY

ENSGT00730000110955_0_Linker_0_1 (253, 293)

NCQIRW--C-----TSPAVEPAADILSPEFHRGQALAAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 354)

-RQPTPIC
CTLLDQRYFSGLGNIIKNEILYLARI--HPLSQGS--LLAVSDLESLLDHAVQFSTDWLH
KKLAGK--GLHYQIYLKEKCPLGHEVMKGTFGPPDGFQRLSWWCPQCQPQVPPEGNKSTH
P-K-----SPSAE-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EAPG-----SSPPPE-PP
QKEAQ--KEGAADPKQAG---EPSGQKTPD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPPGGFQRVTWWCPQCQPQLSEE-LEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MYFGPKALRIH--FG-MKGSIMINPLEHKNKN----G---VSPV-------FELQL
T----KDLICFFDSSVEFRNS-TESQQRVRMMEELDVCS

PF06831 // ENSGT00730000110955_0_Domain_1 (280, 353)

PKFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIRNEALFDSGL--HPAVKVC--QLTDEQTHYLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 448)

DFSILFYR
CHKTGSVISKHYKVYKRPHCCQCCC--KITVCRLGENNRMTYFCPRCQKENPQHV-DICK
LPTRNTTIRWPCSRGEH-----VARKW

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 476)

EEQWACVVCTLINSPSSKTCAACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 661)

PDS--
-VIENEE-HSIAF-TDLVRYPCNSFGKPSKEVKINRKTAFGTTTLVLADFSNKSSALERK
TSQNQTLDGEFQNRSPTHVCFN-DPLHRSEDRANH---GSQPSDKA--NVSPSLCPQSEL
FSPAYKKLKTTHSSSPDLR-SGKP-GF------------PASELGIKLTDGTWALHADRP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHSRRCVLRVVRKDGENKNRQFYACPLPREEQCGFFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKAKQCNFFQWAENGPGVKFIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-RLAA---
-STAVVSP-QAAALNN----N-DSSQNVLS--------LFNGYVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGFIMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQQRIRMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAESEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQIHHLVKMIRDFSILFYR
CRKAGLALSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNTIISWTSSRVDH-VMDSVARKSEEHWTCVVCTLINKPSSKACGACLTSRPIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERK
TKQNQILDEEFQNSPPTNVCLND-IQHPSKKTTND---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHYSSPELK-SCNP-GY------------SNSELQINMTDGPRTLNPDSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSIMINPLECKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQQRVGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRITYFCPRCQKENPQHV-DICR
LPTRNTIISWTSSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCAVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSSKSSTLEIK
KKQNQTLDKEFQNSPPTNVCLKD-TQHPSKKRTNN---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSELQINVTDGPGTLNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLCPDSFQSLW--LQDAQVHGKKLFLRFDPDEEM--ELLG-----SSPQP----
VQGVQ--QKEAMDPELAL---LPNAQETSA-GPSG---SGEPV-PSGSDG-PYDL---GG
HNLL-AVAQRWLEVR--FG-LFGSVWVNDFSRAKQANKRGDWRDPVPR-------LVL--
-HFDGGGFLAFYSCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSSSSLEALVDHVVEFSSDWLR
DKFQGK--GRRTLIYQKDQCPSGHQVMKETFGPPCGLQRLTWWCPQCQPQLSSEGPQNML
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-RGAA-------LQSES-------------------------P-PQ-----RDPGSA---
-SDPLYPT-EAAALNN----NK

PF01149 // ENSGT00730000110955_0_Domain_0 (143, 216)

NSSQDFLR--------LFNGHVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSLIINPVESKNK

ENSGT00730000110955_0_Linker_0_1 (216, 282)

N----G---VSPD-------FEVQL
T----KDLICFFDSSVEIRNA-TESQQRIRVMEELDVCSPR

PF06831 // ENSGT00730000110955_0_Domain_1 (282, 353)

FSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPSVKVC--QLTDEQIHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 448)

DFSILFYR
CCKVGSALSQHYKVYKRPNCGQCCC--KITVCRLGENNRMTYFCPHCQKENPQHV-DICM
LPVRNTTVSWPSSREGH-LIDCVAQKS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEQWTCEVCTLINKPSSKTCDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PADS--
-VFRNEG-NPTVF-NNLVKYPCNSFGKPKAKVKINRKTAFGTTTLVLTDFSNKYSALERE
ESHNHIPDGEFPSP-PPNMCGSD-TLTTSKERTNY---RSQPSDKI--NTSPIVYSQYKL
FSPAHKKLKTTHYSSPDLK-SCNP-GF------------SNSELQSNMTDGPRLLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHGRPCALRVVRKSGENKGRHFYACPLPREAQCGFFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAQNGPGINIIPGC-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MFFGPKALRIH--FG-MKGSILINPLAYKNKN----G---VSPV-------FELQL
T----NDLICFFDSSVELRNS-MESQQRIRMMEELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSFLRAESEVKKQKGRMLC
DVLLDQKVLPGVGNIIKNEALFDSGL--HPAVKIF--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKTGSAISKHYKVYKRPNCGQCHC--KIIVCRLGENNRMTYFCSHCQKENPQHI-DICK
LPSRNTIINWTSSRGNR-LIDSVGRK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 477)

SEEQWTCLVCTLVNKPSAETCDACLTSKP-

ENSGT00730000110955_0_Linker_2_3 (477, 661)

DS--
-VLETQE-NSIVF-HNLVKYPCNSFGKAHTEVKINRKTVFGTTTLVLTDFTSKSSTLKRK
ESQIQTPDGEFQNSLPTNVCFSD-TRHPSKERTNY---ITQVSNKV--NISPTVCSQSEL
FSSVHKKLKTTLYSMPDLK-SCKT-GF------------SNSEPQLSVADSPCTLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCVVRVVRKDGENKGRRFYACPLPREAQCGFFKWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPFEKEKQCNFFQWAENGPGIKIIPGC-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MIRDFTLLFYK
CRKTGSALYKHYKVYKRPNCGQCTG--KIIVCRLGENNRMTYFCPQCQKDKPHLV-DVSK
LPTRNSLIGWAYSKGSC-SNEHVAQKS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEEWICTLCTLINKPSAQICDVCLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PEVS--
-KVQLDE-GSTASNSSLVKYPCNLFGKPNTEIKVNRQTAFGMTTLVLTDLSSELTPLKNG
RSDSQTPDGNSQCDSPRNNSYCQNN-SHQSSGKNYEFHSADLFTA--VNTASHFYHQSDS
SNPVQKKQKIDHLSS-DFKS--NK-SL------------SNSEHRVNMTDGICTLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHNRLCSLRVVRKEGENKGRQFYTCPLPRGTQCEYFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLQF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 749)

PLCNHGKRCIMRTV
LKIGPNNGKNFFVCPLGKDRQCDFFKWADIGPGMKIIPGC-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MFFGPKALRIH--FG-MKGSILINPLAYKNKN----G---VSPV-------FELQL
T----NDLICFFDSSVELRNS-MESQQRIRMMEELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSFLRAESEVKKQKGRMLC
DVLLDQKVLPGVGNIIKNEALFDSGL--HPAVKIF--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKTGSAISKHYKVYKRPNCGQCHC--KIIVCRLGENNRMTYFCSHCQKENPQHI-DICK
LPSRNTIINWTSSRGNR-LIDSVGRK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 477)

SEEQWTCLVCTLVNKPSAETCDACLTSKP-

ENSGT00730000110955_0_Linker_2_3 (477, 661)

DS--
-VLETQE-NSIVF-HNLVKYPCNSFGKAHTEVKINRKTVFGTTTLVLTDFTSKSSTLKRK
ESQIQTPDGEFQNSLPTNVCFSD-TRHPSKERTNY---ITQVSNKV--NISPTVCSQSEL
FSSVHKKLKTTLYSMPDLK-SCKT-GF------------SNSEPQLSVADSPCTLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCVVRVVRKDGENKGRRFYACPLPREAQCGFFKWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPFEKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCKLNGEKIRTQVRPGQVVTG
IRGGA-------PQPPR-------------------------V-P------C-PAVC---
-PGASGSLSWTAPLNS----NKDSCWNFPG--------LLNGCVYSGVET----L----G
KELFMYFGLKALRIH--FG-MNGFVLINPLKSKNQT----K---TPPV-------FEVQL
T----KDLICFYDSSVEFRNA-MESKQKIRMMEDLDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFNFSRAENEVKKQKDRMLC
DVLMDQNVLPGIGNIIKNEALFDSGL--HPAVKVS--QLKDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 449)

DFTIFFYE
CRKTGAALYRHYKVYKRSDCGQCSS--KITVCRLGENNRMTYFCPRCQKENPHSI-DISK
LPTRNNLIGWAYSRGLY-SNECVALRAE

PF00641 // ENSGT00730000110955_0_Domain_2 (449, 476)

EEWSCAVCTLINKPSAKECDACMTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

NDT--
-KKAEDDNNSVAYDNNLMKYPCNNFVKHHTEVKINRKTAFGMTTLVLTDLSNKSSSLESV
RKPNEKPNGGVQNSPVGHICFN-DAQHPSTEKGKA---TILPLDEV--NGSSTFDSQSSL
LSPAHKKMKTNH-TSPELK-SYGT-EFSSMWNASNSRAKSGSELQVNMTDGTCTKNTDS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 700)

P
RCNKHNRLCVLRVVRKDGESKGRQFYACPLPKGSQCGFFKVSISI---------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIQAQVPRGQAVTE
VRGTA-------LRSLR-------------------------S-HA-----S--PAA---
-SAAAVSS-QXXXXXX----XXXXXXXXXX--------X----XXXXXXX----X----X
XXXXXXXXXXXXXXXIHFG-MKGFIRINPLEHKTKN----G---GCPV-------LEVRL
T----KDLICFFDSSVELRNS-MECQQKIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 360)

LDVCSPKFSFSRAENEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDKQIHHLVKMTHDFSILFY

ENSGT00730000110955_0_Linker_1_2 (360, 447)

R
XXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWPCAACTLINMPSSKACDACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

VDS--
-LFRNEE-NSTAF-NSLVKYPCNSFGKSHSEIKINRKTAFGATTLVLTDLTSKSNTFERT
KSPNQILHGEFQNMLSTNVSFSE-ARHPSKERTNY---ITQPSDKV--NIAPVVFSQSKL
FSSAHKKLKTTQYVSRDLQ-SCNP-GF------------SSXXXXXXXXXGPCMLNASS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRIVRKDGENKGRRFYACPLPREAQCDFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PLCNHGKRTIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGINMIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VQGTA-------LQSLV-------------------------G-PA-----T-SPAA---
-SPADVAT-SAA-PMN----AKDSDWKLLR--------LFNGYVYSGVET----L----G
KELLMYFGPRALRIH--FG-MKGSVLINPREGENRS----G---APPA-------FALQL
T----RDLICFYDSSVELRSS-MESQQRVRMMEEL

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 351)

DVCSPKFSFSRAESEVKKQRGRMLC
DVLLDQRVLPGVGNIIKNEALFESGL--HPAVKVC--QLSDEQAHHLVKM

ENSGT00730000110955_0_Linker_1_2 (351, 447)

TRDFSILFYR
CCKAGSAISKHYKVYKRPSCGQCHG--KITVCRFGENSRMTYFCPHCQKESPQHV-QVCK
LPTRNTEINWTPRRKDC-FMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWSCVVCTLINRPSAKACDACLTTR

ENSGT00730000110955_0_Linker_2_3 (475, 660)

PLDS--
-VPKNGE-NSIAF-NNLVKYPFNNFENTHTEIKINRKTAFGNTTLVLTDLSNKSSALARK
KRPNHTIDGESQNFLPTDICFS-DLQHPSKEGINY---IAQPSNKA--NISPTVCAQSKL
FSSAHKKFKTAHSSATELK-SYNS-GL------------SNSELQANRTRGHCSESDGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 704)

P
LCKMHSRRCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 749)

PLCRHGKRSIMKTV
LKIGPNNGKNFFVCPLEKEKQCNFFQWAKNGPGMEIIPGC-

------------------------------------------------------------
------------------------VHGKNLYLNFGLGKDL--EPPN-----SLQLPK-HL
QKEVN--LPKKTNNHKFESTSRLGGQEVPS-SSSD---IK--ASELGEKE-KDSVNEPWW
LNTP-INSEPWLCFH--FG-LFGSVRANELSRATKANKRGDWKDPSPR-------LVL--
-HFEK-GFLAFYNCQMYW--C-----LGPVVKPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 352)

DILSEQFDRRQALEAL--KQANPVC
YTLLDQRYFSGLGNIIKNEVLYLARI--HPLSLGS--CLTSLNLESLLDHVVSFSVGWLQ
KKLEGK--PQHYLIYQKEQCPAGHQIMKDSFGPPNGFQRLTWWCPNCQLKVVSEEPNEVQ
I-T---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SPFVGQQVVR
TGGSSKKLHPDGLQALW--LQDTQV-----------------------------------
------------------------------------------------------------
-----------------------------------------------R-------LVL--
-HFGGGGFLAFYNCQMSWS-------SSPVVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GRAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLALGS--LLSPSRLEALVDHVVEFSADWLQ
GKFQGK--QQHTQIYQKEQCPAGHQVTKEALGPPGGFQRLTWWCPHCQPQLAPKGPEQSQ
V----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 256)

PEGPSVRKFQLLT--SPFVGQVVAK
VGGSSRKLSVNDLNALR--LQDSQVHGKNLYLAFVAAEG--------PVGPTAQE---TA
LQGEA--ACGAHCPAQ----------DGAPHPHSQDEELQE-AQHS-------KS---EA
PEAA-EGQGNWLRIH--FG-MFGSVRANEFSRASRANKRGDWKDPVPR-------LVL--
-HFESGGFLVFYNCR

ENSGT00730000110955_0_Linker_0_1 (256, 297)

MLW--C-----SSPRADPASDILSVEFHRGRALRAL--CAP

PF06831 // ENSGT00730000110955_0_Domain_1 (297, 354)

EPVC
YTLLNQRYFSGLGNIIKNEILYLARI--HPLTPGS--LLARSDLERLLDCAVQFSSEWLH
NKLRGH--GLHPQVYQKEQCPQGHPLMKGTFGPLGGFKRLTWWCPQCQPEV---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQTVTD
VRGRA-------LHSLG-------------------------G-PV-----S-PRAA---
-SVAEVAF-QAAALKD----SEDCSGNFLR--------LFNGCVYSGVET----L----G
KELFMFFGPKALRIH--FG-MKGSIMINPLSYKSKG----E---VSPV-------LELQL
T----SDLICFFDSSVELRNS-VEIQQRIRMMEELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSFLRAESEVKKQQGRMLC
DVLLDQKVLPGVGNIIKNEALFDSGL--HPAVKVF--QLTEEQTHHLVKMVR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKTGSAISIHYKVYKRPSCGQCCH--KITVCRLGENNRMTYFCPRCQKENPQHI-DICK
LPTRSTIIHWTSSKRDP-LTDSVSRK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCLVCTLINKPSAETCDACFASK

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-VFKNEE-NSVVF-HNLVKYPCNSFGKAHTEVKINRKSVFGTTTLVLTDFSNKSSTLKRR
ESQTQTPDGEFQNSLPTNVCFSG-TRHPSKERTNY---ITQVSSKV--NTSPTVCSQSEL
FSSAHKKLKTTHYSTADLK-SCNT-GF------------SNSELQTGITDGPCALSASSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCRKHNRLCVLRVVKKHGENKGRRFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PYCNHGKRSVMRTV
LKIGPNNGKNFFVCPFEKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCALNAEKIRARVRPGQAVTS
VRGSA-------IQPPG-------------------------P-PR-----S-PAAF---
-PGTSASSPWIAPMNS----EKD

PF01149 // ENSGT00730000110955_0_Domain_0 (144, 216)

SCWNFPE--------LLNGCVYSGVET----L----G
KELFMFFGLKALRIH--FG-MNGSVLINPPKSKDQ

ENSGT00730000110955_0_Linker_0_1 (216, 281)

A----R---APPA-------FEVLL
T----KDLICFCDSTVELRNS-LESKQRIRMMEDLDVCSP

PF06831 // ENSGT00730000110955_0_Domain_1 (281, 353)

KFNFSRAESEVKKQKDRMLC
DVLLDQNVLPGVGNIIKNEALFDSGL--HPAVKVS--QLNDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 449)

DFTILFYR
CRKTGSALYRHYKVYKRSDCGQCCS--KITVCRLGENNRMTYFCPRCQKENPQFL-NISK
LSTRNSIIGWAYSRGLY-PNEHVAQKME

PF00641 // ENSGT00730000110955_0_Domain_2 (449, 476)

EEWTCAVCTLINKSSAKECDACMTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

NDA--
-KAEEDANNSITYDNSLMKYPCNNFVKRHPEVKINRKTTFGMTTLVLTDLSNKFSSLENI
RNQNLEPSGDFQNSSVGNICFS-NAEHTSKEKDKY---MTLISDKV--NGSPVFDSQSN-
LSPAQKKLKTNH-SFPEPK-NCSL-NFSSMYNASNNGLPSFSEFQVNMTDSTCTKTTDS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 703)

P
RCNVHKRLCVLRVVRKDGENKGRQFYACPLPRGSQCGFFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 748)

PFCNHGKRSIMRTV
LKVGPNNGRNFFVCPLGKDKQCNFFQWAPNGPGIEIIPRC-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------IH--FG-MKGSVMINPHGHKNKN----G---VSPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQQRIRRMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPKFSFTRAQNEVKKQQGRMLC
DVLLDQKVLPGVGNIIRNEALFDSGL--HPAVKVC--QLADEQILHLVKMIRNF

ENSGT00730000110955_0_Linker_1_2 (355, 447)

SILFYR
CNKTGSAVSKHYKVYQRPNCGQCCC--KIIWCRLGENNRMTYFCPRCQKENPQHI-DISK
LPIRNTVMNWTCSRRDV--LDLVAQK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWACVVCTLINKPSSNACDACMSSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

SDL--
-LHKNKE-NSIAF-SNLMKYLYNNFGKPNTEVKINRKTAFGTTTXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX----XX-XXXXXX---XXXXXXXX--XX--X----X--
XXXXXXXXXXXXXXXXXXX-XXXX-XXXXXXXXXXXXXXXXXELQINGTDGTCALNTGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSEHNRLCVLRIVRKDGENKGRQFYACPLPRETQCGFFKWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 752)

PFCNHGKRCIMRTV
LKIGPNNGRNFFVCPLGKEKQCSFFQWAE-NPGIKVIAGC-

----------------------------------MPEGPLVRKFHHLV--SPFVGQQVVK
TGGSSKKLNPTSFQSLW--LQDTQVHGKKLFLRFDPDEET--VSLR-----NSPLSE-PL
RKGEQ--KNKARHHQEAS---DPSSRSL----------GGDSAVPSGDDG-LQCL---RG
DTPA-GGAERWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPIPRCFWHHPVLVL--
-HFSGSGFLAFYNCQMAWR-F-----SSPVVSPTSDILSEKFHRGQALEAL--GR

PF06831 // ENSGT00730000110955_0_Domain_1 (296, 353)

ELPVC
YTLLDQRYFSGLGNIIKNEALFRARI--HPLSPGS--LLGLPRLEALVDHVVAFSADWLQ
GKFQGT--QQHTQIYQKEQCPGGHQVVKESLGPPGGFQRLTWWCPQCQPRLSADEPKQVQ
P----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EPPG-----SSPPPE-PP
QKEAH--KEGAVDPKQDG---EPSGQKTLD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSETFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKDQCPAGHQVMKEAFGPPGGFRRLTWWCPQCQPQLSEE-PERRQ
V-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPSVRKFHRLV--SPFVGQQVVK
TGGSSQKLTPASLQSLW--LQDTQVHGKKLFLRFEPDEEL--GSLD-----NISLPE-SL
EKGER--KEEAQDQKQAS---GPSSQKTSQ-PPSQ---SLEHVAPSGDSG-LEGL---RG
DAAV-GAAERWLQVS--FG-MFGSIWVNEFSRAKKANKRGDWRDPIPR-------LVL--
-YFGGGGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 276)

CQMSWS-------SSPVVRPAS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DILSEKFDRRQALEAL--SQEQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSHQHLEALVDHVVEFSVDWLQ
GKFEGR--QQHPQIYQKEQCPGGHRVMREAFGPPGGFQRLTWWCPQCQPRLSPDEQGQVQ
L----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MYFDQKALRIH--FG-MNGSMHINPDGSKDRN----G---AQPV-------LEIQF
M----EETVCFWDVTVEYRNA-AECEQKVRMMESLDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 351)

SPKFSFSRAEHEIKQQKARMLC
HVLLDQAVLPGVGNIIKNEALFDSGL--HPALKVC--QLTDEHIRHLVKMTRDFTLLFYK
CRKTGSPLYKHYKVYKRPACSECSG--SITVCRLGDHDRMTYFCSRCQKADPKLV-NLSK
LPARNSLIGWACGRGSC-SNEQVARKSEEEWTCMQCTLINKPSAEICDACLTSRPEVP--
-KMESSE-DSAAFNTNLMKYPCNEFRKPSTEIKINRKTAFGTTTLVLTDLGNKTVL----
RNDPQGSDGRSQCVVPTSNCKQIQSNACQSGGSTEEECSTHVTA-----LALSSCQQPIT
FKHIQKKQKTDHVPL-VHPHNIPI-S----------------TPRTNVTDDTQMLSMGHP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHSRLCSLRVVRKDGENKGRQFYCCPLPRETRCDYFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLDF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 748)

PFCNHGKRSVMKTV
LKIGPNNGKNFFVCPLGKEKQCGFFQWAANGPGMQIFP---

----------------------------------MVEGPCCALF

PF01149 // ENSGT00730000110955_0_Domain_0 (45, 211)

AERLRARVHRGQVVRS
ARGSA-------LSTE--------------------------------------------
-------ARAATVASE----ER---TSSHD--------FLTGQVFRGVET----L----G
KELFMYFDQKALRIH--FG-MNGSMRINPD

ENSGT00730000110955_0_Linker_0_1 (211, 279)

GRQDRS----G---ALPV-------LEIRL
T----EDTICFFEVTAEYRNV-TECEQRVRMMESLDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 351)

SPKFSFLRAESEVKQQKTRMLC
DVLLDQRVLPGVGNIIKNEALFDSGL--HPAAKVC--QLTDEHIRHLVKMTRDFTLLFYK
CRKTGSPLYKHYKVYRRQTCSQCNE--KITVCRLGENNRMTYFCSRCQKADPQLV-NVSK
LPTRNSLIGWACGRGSC-SNEHIAQKCEEEWTCMRCTLINKPSAEACDACLTSRPEVSSS
LKTENVE-DSADFNINLIKYPCNEFRKPSTEIKINRKAAFGNTTLVLTDLGNKAVL----
KGDIQVSDGCSDYVAPKGNFSHNQSNVYHSVISIDKYCSTDVTS-----AASSSCQEPLS
FKHIKKKQKTHHVPS-VHQYNVTI-G----------------KPQVNLTDDIHTPSTGPP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

HCSKHGHLCKLRIVRKDGENKGRMFYSCPLPPETQCNYFQWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCHHGKRCVMKMV
LKLGPNNGRNFFVCPLQKEKQCGFFQWAENKPVTPSIP---

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGTA-------LQSLL-------------------------G-PA-----T-SPAA---
-SPADVAT-SAA-PMN----AKDSGWKLLR--------LFNGYVYSGVET----L----G
KELFMYFGPRALRIH--FG-MKGSILINPREGENRG----G---ASPA-------LAVQL
T----SDLICFYDSSVELRNS-VESQQRVRMMEEL

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 351)

DVCSPKFSFSRAESEVKKQRDRMLC
DVLLDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--QLSDKQARHVVKM

ENSGT00730000110955_0_Linker_1_2 (351, 447)

TRDFSILFYR
CCKAGSAISKHYKVYKRPNCGQCHS--KITVCRFGENSRMTYFCPHCQKENPQHV-QVCK
LPTRNAEISWTPRGEDC-FTDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWSCAVCTLINRPSAKACDACLTTR

ENSGT00730000110955_0_Linker_2_3 (475, 660)

PLDS--
-VLKNGE-NSIAF-NNLVKYPCNNFENTHTEIKINRKAAFGNTTLVLTDLSNKSSALARK
KRANHTIDGESHMFLPTDICFS-DSQHPSKEGMNS---IAQPSNKV--NISPTACAQSKL
FSSAHKKFKPAHSSATELK-SYNS-GL------------SNSELQTNRTRGHHSESDGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 704)

P
LCKMHHRRCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 749)

PFCRHGKRSIMKTV
LKIGPNNGKNFFVCPLEKEKQCNFFQWAKNGPGMEIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPLVRKFHHLV--SPFVGQQVVK
TGGSSKKLNPTSFQSLW--LQDTQVHGKKLFLRFDPDEET--VSLH-----NSPLSE-PL
RKGEQ--KDKARNHQEAS---DPSSRSP----------GGDSAVPSGDDG-LQCM---GG
DTPA-GGAERWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPIPR-------LVL--
-HFSGSGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 296)

CQMAWR-F-----SSPVVRPTSDILSEKFHRGQALEAL--GR

PF06831 // ENSGT00730000110955_0_Domain_1 (296, 354)

ELPVC
YTLLDQRYFSGLGNIIKNEALFRARI--HPLSPGS--LLGLPRLEALVDHVVAFSADWLQ
GKFQGT--QQHTQIYQKEQCPAGHQVVKESLGPPGGFQRLTWWCPQCQPRLSADEPKQVQ
P----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFQLLT--SRFVGQVVAK
VGGSSKKINVNDLNALR--LQDSQVHGKNLFLAFVAASS--------PLGPNVEE---TV
LQEEA--ATGASSLVQ-----GKQEQVCAPLTPPQEEELQD-LQNS-------RP---GA
PSAPTEGPGSWLRFH--FG-LFGSIRANEFSRASRANKRGDWKDPAPR-------LVL--
-YFESGGFLVFYNCRMHW--C-----SSLVADPTSDILSAEFHRGQALDAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 354)

-RTSRPIC
YTLLDQRYFSGLGNIIKNEVLYLVKI--HPLTQGS--LLAQSDLEHLLDCAIQFTSNWLQ
SKLQGK--GLHLQIYQKEQCPLGHVVMKGALGPPGGWKRLTWWCPQCQPAVLSGDGGPTL
G-I-----E---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------

PF06831 // ENSGT00730000110955_0_Domain_1 (313, 353)

GNIIKNEILYLAKI--HPLTQGS--LLASSDLEHLLDCAIQFSLDWLQ
SKLRDE--GLHFQIYQKEQCPLGHAVLKGTFGPSGGYKRLTWWCPQCQPAVLCPDSLRKV
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFQLLT--LSFVGQVVAK
VGGSSKKINVNDLNALR--LQDSQVHGKNLFLAFVAASS--------PLGPSVDE---TE
LQKEA--ATGPSSLVQ-----GKQEQVCAPLTPPQEEELQE-LQNS-------RP---GA
A----GGPGSWLRFH--FG-LFGSIRANEFSRASRANKRGDWKDPIPR-------LVL--
-YFESGGFLVFYNCRMHW--C-----SSPVADPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 363)

DILSAEFHRGRALDAL--RTSHPIC
YTLLDQRYFSGLGNIIKNEVLYLVKI--HPLTQGS--LLAQSDLEHLLDCAIQFTSDWLQ
SKLQGK--GLHLQIYQKEQCPLGHVVMKGALGPPGGWKRLTWWCPQCQPAVLSGDGDLTL
G-I-----E---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTD
VRGSA-------LQGLE-------------------------G-RG-----L-PHAA---
-SVAAGAS-QAAALNN----NKDSSWNFLR--------LFNGYTYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSIMINPLGHKNKN----G---VSPV-------FEVQL
T----KDLICFFDSSVELSKTHWKVQQRIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPKFSFLRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTLHLVKMIRNF

ENSGT00730000110955_0_Linker_1_2 (355, 446)

SILFYR
CNKAGSAVSKHYKVYKH----QCYC--KITVCRLGENNRMTYFCPQCQKEDPQHV-DISK
VPTRNTVISWPCSRMD--VLDSVAR

PF00641 // ENSGT00730000110955_0_Domain_2 (446, 476)

KAEEQWACGVCTLINKPSAKACDACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

NDS--
-VLKDEE-NSIAF-SNLVKYPCNNFGKPNTEVKINRKTAFGTATLVLTDFSNKSSTLEGK
KSQNQILDGEFHTSAPTGFCFG-DTQHPSEERTNY---VTQLSSKV--NISPTVGPRSKL
FSPAHKKLKTVH-SSPDLK-SRKP-GF------------SNSELQIHGTDGTWALNAGS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGRNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLCPDSFQSLW--LQDAQVHGKKLFLRFDPDEEM--ELLG-----SSPQP----
VQGVQ--QKEAMDPELAL---LPNAQETSA-GPSG---SGEPV-PSGSDG-PYDL---GG
HNLL-AVAQRWLEVR--FG-LFGSVWVNDFSRAKQANKRGDWRDPVPR-------LVL--
-HFDGGGFLAFYSCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSSSSLEALVDHVVEFSSDWLR
DKFQGK--GRRTLIYQKDQCPSGHQVMKETFGPPCGLQRLTWWCPQCQPQLSSEGPQNML
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 255)

PEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLNPTSFQSLW--LQDSQVHGKKLFLRFDPDEEA--VSLG-----NSLLSE-PL
REGEQ--KDKARHHQEAS---DPSSWSP----------GGDSAVPSGDDG-LQCL---GG
DTPA-GGAERWLQVS--FG-LFGSIRVNEFSRAKKANKRGDWRDPVPR-------LVL--
-HFSGSGFLAFYNC

ENSGT00730000110955_0_Linker_0_1 (255, 278)

QMTWR-F-----SSPVVSPASDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GREQPIC
YTLLDQRYFSGLGNIIKNEALFRAGI--HPLSPGS--LLGLPRLEALVDHVVAFSADWLQ
GKFQGT--RQHTQIYQKEQCPAGHQVVRESLGPPGGFQRLTWWCPQCQPRLSADEPKQLQ
P----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHRLV--SPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDTQVHGKKLFLRFDLDEEM--GPPG-----SSPTPE-PP
QKEVQ--KEGAADPKQVG---EPSGQKTLD-GSSR---SAE-LVPQGEDD-SEYL---ER
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-HFGGGGFLAFYNCQLSW--S-----SSPVVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--VLSASRREVLVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEE-PEQCQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTD
VQGSA-------LQSLG-------------------------V-SG-----F-PHAA---
-SVAAFSS-QAT-QNN----HKDSSQNSLR--------LFNGHLYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSIMINPLEYKNKN----R---NSPV-------LKVQL
T----KDLICFFDSSVELRNS-TESQQRIRMMEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 355)

LDVCSPKFSFSSAEREVKKQTGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAIKVC--QLTDEQIHHLVKMIHDF

ENSGT00730000110955_0_Linker_1_2 (355, 446)

SILFYR
CRKAGSIVSKHFKVYKRPNCGRCCC--KITVCRLGENNRMTYFCPHCQKENPQHV-DVRK
LPTRNTTISWTSSSGDH--VDEVAR

PF00641 // ENSGT00730000110955_0_Domain_2 (446, 476)

RCEEQWTCLVCTLINRPSSKACDACLTARP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

IDS--
-TLENAE-SSIAC-NNLVKYPYNSFGKPSTEIKINRKTAFGATTLVLTDFSNKSITSKRK
KSQNQTPNGEFQNSSPTNVGFS-DTPDPLEERANN---MAQPSNTV--NLSPMVCSQSKL
CSSAYKKLKRTHYSSPGLE-SCNP-GL------------SNSELQINMTDGTCTLTAHS

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

SF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRSIMRTV
LKIGPNNGKNFFACPLGKDKQCNFFQWAENGPGINILPC--

----------------------------------MPEGPLVRKFHHLV--SPFVGQQVVR
TGGSSRKLEPASVQSLW--LQDAQVHGKKLFLRFDPDEET--GPPG-----NSPPPE-PP
QKDAQ--KEGAADPRQAQ---EPCGQKTSD-GSSR---SAE-LVPQGEGD-SQCL---AG
AAPA-GGAGRWLCVC--FG-LFGSIWVNEFSRAKKANKRGDWRDPAPR-------LVL--
-HFGGGGFLAFYNCQMSW--S-----SSPAVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 353)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQKHFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSASQREALVDGVVEFSAAWLQ
DKLQGH--PQHTQVYQKEWCPAGHQLLKEAFGPPGGFQRLTWWCPQCQPQLSEE-LEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAMTG
VRGTA-------LQGLL-------------------------G-SA-----L-SPAA---
-SLAEVTS-SAA-PMN----AKDSGWKVLR--------LFNGCVYSGVET----L----G
KELFMYFGPRALRIH--FG-MKGSILINPPKCENRG----G---VSPA-------FEVQL
T----NDLICFFDSSVKLRNS-VESQQRVRMME

PF06831 // ENSGT00730000110955_0_Domain_1 (274, 351)

GLDVCSPKFSLSRAESEVKKQRDRMLC
DVLLDQRVLPGVGNIIKNEALFDSGL--HPTVKVC--QLSDKQAHHLVKM

ENSGT00730000110955_0_Linker_1_2 (351, 447)

TRDFSILFYR
CRKAGSAISKHYKVYKRPNCAQCHC--KIRVCRLGENSRMTYFCPHCQKENPQHV-QICS
LPFRNAEISWTPKGQDC-FTDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWSCMVCTLINKPSATACDACLTTR

ENSGT00730000110955_0_Linker_2_3 (475, 660)

PVDS--
-VLKNEE-NSIAF-SNLVKYPFNNFENTHTEIKINRKTVFGNTTLVLTDLSNKSSALARK
SSPSQTIDGESQIFLPTDICFS-DPQHISKEGVNY---ITQPSNKV--NMSSTVGAQSKL
FTSAHKKLKTAHSLATELK-SYNS-GL------------SNSELQTNIRSDPCSLHASR

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 704)

P
QCKTHSRPCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCGHGKRSIMKTV
LKIGPNNGKNFFVCPLEKEKQCNFFQWAESGPEMEIIPGC-

----------------------------------MVEGPGCTLNGEMIRARVLPGQAVTG
VRGSA-------LRNPQ-------------------------G-RA-----L-PLAA---
-SSAVVSP-QAAALNN----N-DSSQNVLS--------LFNGYVYNGVET----L----G
KELFMYFGPKALWIH--FGMK---------AINLKN----G---TSPY-------FVNIV
T----R-LMVMCVYIPFYRNS-TESQQRIRMMKELDVCSPTFSFLRAESEVKKQKGRMRV
A---------WSREIIKNEALFDSGL--HPAVKVC--QLTDGQIHHLVKMIRDFSILFYR
CRKAGLAVSKHCKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNCVISWTPSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VVKNEE-NSPAF-SNLVKYPCNTFGKPHTEVKINRKTTFGTTTLVLTDFSNKSSTLERK
TEQNQILDEEFQISPPTNVCLSD-TQQPSKKRRND---ITQPSSKA--NISPTVSSESKL
FSPTHKKLKTAHYSSPDLK-SCNP-GY------------SNSELQINMTDGPRTLNPGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVRKDGENKGRHFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFGCPLGKEKQCNFFQWAENRPGIKIIPGC-

----------------------------------MPEGLLVRTFHHSV--SPFVGKQVVK
TGSNSKN-----LQSLW--LQDTQVHGKKLFLRFDPDEEM--GPAG-----NSSPPE-PP
QKEAQ--MEGTVD---------SNGQKTLD-ASSR---SAE----------LECL---KG
DTPT-GDAGRRLRVS--SC-LFGSVWVNDFSRAKKANKRGDWRDPAPR-------LVL--
-YFGGGSFLALYNCQMPW--S-----SSPEVTPTS------------LEAL--GQA

PF06831 // ENSGT00730000110955_0_Domain_1 (297, 353)

QPVS
YTPLNQKYFSGLGNVIKNEVLYRTGI--HPLSLGS--VLS----EALVDHVVEFSTAWLQ
GKFQGK--PQHMQVYQKEQCPAGHQVMKKPFGPSGGFQRLTWWCPQCQSQLLEEPEQ---
---------WTQGALHG-------------------TLP-LGEPDV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRNLQ-------------------------G-RA-----L-FLAA---
-PSAVVSP-QAAVLNN----K-DSSQNALS--------LFNGYVYDGVET----L----G
KELFMYFGPKALRIH--FG-MKGCVMINPLEYKYKN----G---ASPV-------LEMQL
T----KDLICFFDSSVELRNS-MDSQQRIRMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPTFSFLRAESEVKKQKGRMLG
DVLMDQSVLPGVGNIIKNEALFDSAL--HPAVKVC--QLTDGQIHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHCKVYKRSNCGQCLG--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNSVISWTPSRVDH-VMESVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINEPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VVKNEE-NSTAF-SNLVKYPCNTFGKPHTEVKINRKTTFGTTTLVLTDFSNKSSTLERK
AKQNQILDEEFQISPPTNVCLSD-TQHPSKKRTND---ITQLSSKA--NVSPTVSSESKL
FSPTHKKLKTAHYSSPDLK-SCNP-GY------------SNSELQINMTDGPRTLNPDTP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILQVVRKDGENKGRHFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFGCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 255)

PEGPSVKKFQLLC--SPFVGQTVIK
VGGSTKQMTPNDVKTLV--LSDAQVHGKKLFLAFGPPQKGTTGSRIEH--SESPA-----
GQGLT-----------DS---GSSSFLMRQEGKVADTHDLKDHLQEEHDVDWPSL---A-
-EDNADGPRKWLRFQ--FG-LYGSIRANEFARANKANKRGDWRDPVPR-------LIL--
-NFEGGGFLVFYNC

ENSGT00730000110955_0_Linker_0_1 (255, 295)

RIQP--C-----SSPSNEPSTDILSPEFDRGKALEAL--C

PF06831 // ENSGT00730000110955_0_Domain_1 (295, 355)

KPTPVC
YTLLNQTYFSGLGNRIKNEALYLARI--HPLSLGS--QLPSCDLESLLDSAVQFSLEWLQ
SKLQKK--SVQVHIYMRDKCPAGHEVKKEALGPPDGLKRLTWWCPQCQPQVSQGEMDMPS
T-E-----SN--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 206)

PEGPSVRVFHQRV--SPFVGQRVAS
AGGSTRKLEPAALQGLR--LVETQVHGKILFLRFDPDEET--GGQ--------SAPE-PG
AAGPR--E-------------GPGGQ---------------------------EG---PA
RCPG-GTAGMWLQVR--FG-LFGSIRRNEFSRATQANKRGDWRDPTPR-------LLL--
-RFVGGSFLTFYACQLTC--C-----PGPMGTATSDILSQMFQRGQALEAL--RQARPVC
YTLMEQRHFSGL------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHQLV--SPFGGQRWSR
QGAAARSYTHV-TFNLW--LQDTQVHGKKLFIRFDPDEEL--ETHG-----NDPLPE-TL
HK------VEAVDQQQTV---GPSRQLLTS-PPGL---SLPIQWRQGT------------
QMSR-GGSPHVATSQ--LH-LFGSIWVNQFSRVKKANKSGNWRDPAPR-------LVL--
-YLGSGSFLVFYDCQMSW--S-----SSLVVRATSDILSEKFHGGQALEAL--DWVH

PF06831 // ENSGT00730000110955_0_Domain_1 (298, 346)

PVC
YTLLDQRYFSGLGNV-KNKVLYRARV--HLLSLKL--LLSPSHLEA-MDHMVEFSTNWLH
DKLQDR--QQ--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EAPG-----SSPPPE-PP
QKEAQ--KEGAADPKQAG---EPSGQKTPD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
ITLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPPGGFQRVTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLHPASFQALW--LQDAQVHGKKLFLQFDPDEEM--ELLG-----SGPQP----
GQGVQ--QKEAMNPELIL---GPNAQEMSA-GPSG---SEEPF-PSGSDG-PYGL---GG
HNLL-AVAQRWLEVR--FG-LFGSIWVNDFSRAKKANKRGDWRDPVPR-------LVL--
-HFDGGGFLAFYNCQMSWS-------PPPVVEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DILSEKFHRGQALEAL--RQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSSSSLEALVDHVVEFSSDWLR
DKFQGK--KQHTQIYQKQQCPSGHQKLLSS------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTG
VRGRA-------LQSLV-------------------------G-PA-----L-PPAA---
-SQVEVSS-QAA-TVN----TKDCGWEFLR--------LFNGYVYSGVET----L----G
KELFMYFGPIALRIH--FG-MKGFISINPGECENRG----G---VSPT-------FQVQL
T----RDLICFFDSSVELRNS-TESQQRVRMMEELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSLSRAESEVKQQKDRMLC
DVVLDQRVLPGVGNIIKNEALFDSGL--HPAVKVC--ELSEEQTHHLVKMIRDFSILFYR
CHKAGSAISKHYKVYKRPNCGQCHC--KITVCRLGENSRMTYFCPHCQKENPQHV-QLCK
LPTRKAVISWTSGREDC-LMDSVARKFEEQWSCVVCTLINKPSAEACDACLTVRPVDS--
-VLKNEE-NNIAA-SNLVKYPCNNFGNTHTEVKINRKAVFGSTTLVLTDFSNKSSTSARK
KSPNQIIGGGFQNFLPTDVCFS-DLQHPSKEGANY---ITQPSNRV--NISPTVCAQSKL
FSSAHKKLKTAHSSEADPK-YYNP-GL------------SNSERQTSTTDGPRSVNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCKKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PLCKHGKRSIMRTV
LKIGPNNGKNFFVCPLEKEKQCNFFQWAESGPGMEIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSIMINPLECKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRVGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPRCQKENPQHV-DICR
LPTRNTIISWTSSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEMK
KKQNQTLDKEFQNSPPTNVCLKD-TQHPSKKRTNN---ITQLSSKV--NIAPTISSEPKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSELQINVTDGPRTLNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNIGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-PLAA---
-STAVVSP-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSIMINPLECKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRVGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPRCQKENPQHV-DICR
LPTRNTIISWTSSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-MLKNEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
KKQNQTLDKEFQNSPPTNVCLKD-TQHPSKKRTNN---ITQLSSKV--NIAPTISSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSELQINVTDGPRTLNPDGP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHSRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTD
VRGSA-------LQNAG-------------------------G-PG-----L-PLSA---
-SETVVPS-QAIALNN----NKLCSQNSLR--------LLNGHVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSLAINPLESKSKN----G---VSPV-------FEVQL
T----KDLICFFDSSVEIRNT-AESQQRIRMMEEL

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DVCSPKFSFSRAEREVKKQGGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIH

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKAGSAVSKHYKVYKRPNCGQCFC--KITVCRLGENNRMTYFCPHCQKENPQHV-DICL
LPARNTFVPWPSSRENH-FTDCVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCEVCTLINKPSSQACDACLSSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-VLENKE-NPTAL-NNLVKYPCNSFGKPRTEVKINRKTAFGTTTLVLTDFSNKSSALKRE
ESQKQILDGEFPNP-L-----------SSPERANY---ITQLSNKV--NVLPMICTQSKI
FSPAYTNLKTTHYSSPDHK-TCNP-GF------------SNSELQINTTDGPHTLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHGRPCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGINIIPGC-

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLNPASFQFLW--LQDAQVHGKKLFLRFDPDEEL--GSLG-----NVSLPE-PL
QKGER--EEEDQDQKQAL---RPSSQNISN-EPSQ---PLELVIPSGDSG-LECL---QG
DTSAGGGAERWLQVS--FG-LFGSIWVNEFSRAKKANKRGDWRDPIPR-------LVL--
-YLSGGSFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 293)

CQMSWR-------SSALVQPTSDILSEKFHRGQALEAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 354)

-GREQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPRHLEALVDHVVEFSADWLQ
GKFQGK--QQHTQIYQKEQCPFGHPVMKDAFGPPGGFQRLTWWCPQCQPRLPPNEQEQAQ
H----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKFCPTGLQALW--LQDTQVHGKKLYLRFDPDEVG--PPGN-----NNPLPE-HP
QKGAQ--REEALGSSRQ--------GTCDE--ALH---SSELVAPQGADG-SDCL---RR
DPPA-EGPERWLQIR--FG-LFGSVWANEFSRAKKANKKGDWQDPSPR-------LVL--
-HFGAGGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 290)

CQMAWR-------SSPVVEPTCDILSDEFHRGQALE

PF06831 // ENSGT00730000110955_0_Domain_1 (290, 353)

AL--GQARPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLALGS--LLSPSRLEALVDYVVEFSTGWLQ
GKLQGI--SQHKQIYQKEHCPAGHQVMKEALGPPGRFQRLTWWCPHCQPQLSIEKPEESQ
L----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------M

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 254)

PEGPSVRKFHHLV--SPFVGQQVVR
TGGSSKKLNPASFQSLW--LQDTQVHGKKLFLRFDPDEEI--GSSG-----NNPLPE-SL
QKGER--KEEAGDQKQAL---GPNSQNTDQ--PSQ---SREVVVPGGEDA-LECL---GG
DGPA-GGAERWLQVR--FG-LFGSIWVNEFSRAKKANKRGDWRDPVPR-------LVL--
-HFGGGGFLAFYN

ENSGT00730000110955_0_Linker_0_1 (254, 290)

CQMSWS-------SSPVVRPTSDILSEKFHRGQALE

PF06831 // ENSGT00730000110955_0_Domain_1 (290, 354)

AL--GQEQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPPRLEVLLDHVVEFSADWLQ
GKFQGK--QQHTQIYQKEQCPAGHQVMKEAFGPPGGFQRLTWWCPQCQPRLPPSQPEQVQ
L----------------------------------------P------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------VHGKKLFLRFDSDEEI--ELPG-----SRSPPE-PL
QKR----KKEARDQKQVL---GPKCRKISD-TSPR---SPECPVPSGDSS-GSCV---GG
DAPA-NSAEKWLQLS--FG-MFGSIWVNEFSRAKKANKRGDWRDPIPR-------LVL--
-HFGGGGFLAFYNCQMSW--G-----SCPVVTPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 355)

DILSEHFHRGQALEAL--GQAQPVC
YTLLDQRHFSGLGNIIKNEVLFRAGI--HPLSLGS--TLSPPRLEALLDQVLDFSACWLQ
GKLQSQ--PQHTQIYQKESCPAGHRVQKEALGPAGGLKRLTWWCPQCQPQEPSEESQCTD
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHYLV--TPFVGQQVVK
TGGSSKKLHPPDLQSLW--LLDTQVHGKKLFLRFDPDEET--ETPD-----HNPLPE-PL
GEGLQ--KEDASCQKQAI---GPNGLKISD-------GSSELVVPKADDG-SEYS---QG
DAPA-GGAERWLKVR--FG-LFGSIWVNVS--REKANKRGDWRDPVPXXXXXXXXXXX--
-----XXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXX
XXXXXXXXXXXXX

PF06831 // ENSGT00730000110955_0_Domain_1 (314, 353)

NIIKNEALYRAGV--HPLSLGS--HLSPSRLEALVDHVVEFSTNWLQ
DKLQGE--QQHTQVYQKEQCPSGHQVMKEAFGPPGGFQRLTWWCPQCQPRVPPEEPEQLL
F-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVVK
TGGSSKKLHPDSFQSLW--LQDAQVHGKKLFLRFDPDEE---ELHG-----SSPPP----
VQGVQ--QREAMNPELAL---RPSAQETFT-GPSG---SGEPV-PSGSDG-PSGL---GG
HNLL-VVAQRWLEVR--FG-LFGSVWVNDFSRAKQANKRGDWRDPVPR-------LVL--
-HFDGGGFLAFYSCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 353)

DILSEKFHRGKALEAL--SQAQPVC
YTLLDQKYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSSSSLEALVDHVVEFSSDWLR
DKFQGK--GRHTLIYQKEQCPSGHQVMKETFGPPCGLQRLTWWCPQCQPQLSSEGP----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTD
VRGRA-------LQGLG-------------------------G-PG-----S-PPAA---
-PGPMGTS-QAAALNN----NK

PF01149 // ENSGT00730000110955_0_Domain_0 (143, 215)

NSSQDFLR--------LFNGHGYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGSLVINPLESKN

ENSGT00730000110955_0_Linker_0_1 (215, 282)

KN----G---VSPV-------FEVQL
T----KDLICFFDSSVEIRNS-TESQQRIRVMEELDVCSPR

PF06831 // ENSGT00730000110955_0_Domain_1 (282, 353)

FSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGF--HPSVKVC--QLTDEQIHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 448)

NFSILFYR
CCKVGSALSKHYKVYKRPNCGQCCC--KITVCRLGENNRMTYFCPHCQKENPQHV-DIRM
LPVRNTTVNWPSSRERH-LMDCVAQKS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEQWTCEVCTLINKLSSKTCDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PADS--
-VLRNEG-NPIVF-NNLMKYPCNSFGKSKAKVKINRKTAFGTTTLVLTDFSNKHSALERE
ESHSHIPDGEFPSP-PPNVCGSD-TLNTSKERTNC---RSQPSDKV--NISPVVCSQYKL
FSPAHKKLKTTHYSSPDLK-SCNP-GF------------SNSELQSSMTDGPCLLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHGRPCALRVVRKSGENKGRHFYACPLAREAQCGFFEWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAQNGPGINIIPGC-

----------------------------------MPEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLHPAELQSLW--LQDTQXXXXXXXXXXXXXXXX--XXXX-----XXXXXX-XX
XXXXX--XXXXXXXXXXX---XXXXXXXXX--XXX---XXXXXXXXXXXX-XXXX---XX
XXXX-XXXXXXXXXX--XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX-------LVL--
-HFGGGGFLAFYNCQMSWS-------SSPEVKPSS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 361)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGV--HPLSPGS--LLSPSSLESLVDHVVAFSTDWLQ
GKFQGK--QQHTQVYQKEQCPVGHQVKKDTFGPPGRFQRLTWWCPQCQPRLPAEEPEQLQ
P-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------VHGKKLFLRFDPDEEM--GPSG-----NIPLLQ-PL
QKGVR--KEETGAQTCTL---EPSGQ-ISD-QSSR---AMELVVTNGEDS-AEFG---GG
DTPA-GNAERWLQVR--FG-LFGSIWMNEFSRAKKANKRGDWRDPAPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SYPVVKPTS

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 361)

DILSEKFHRGQACKAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPSSLESLVAHVVEFSTDWLQ
GKFQGK--QQHTQIYQKEQCPAGHQVRKEAFGPPGGLQRLTWWCPECQPRVPAEEPEQVQ
L-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVRPGQAVTA
VRGSA-------LQSLG-------------------------G-PA-----W-GAA----
-AGAVVPA-QAAA

PF01149 // ENSGT00730000110955_0_Domain_0 (134, 226)

LKN----KEDSSQNVSR--------LFDGYVYSGVET----L----G
KELFMYFGPKALWIH--FG-MKGSIIINPPEDKKKD----G---V

ENSGT00730000110955_0_Linker_0_1 (226, 281)

SPV-------FEVQL
T----KDLICFFDSSVELRNS-TESQQRIRIMGELDICSP

PF06831 // ENSGT00730000110955_0_Domain_1 (281, 353)

KFSFSRAESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 448)

DCSILFYK
CRKAGCAISRHYKVYKRPNCGQCCC--KITVCRLGENHRMTYFCPHCQKENPQHV-DICK
LPTRNSTISWTSSRDNH-LMDHVARKS

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEQWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-ILKNED-SSIAY-SHLVKYPCNSFGNPNTEVKINRKTAFGTTTLVLTDFSNKSNALERK
TSQNQTLDGEFQNSSPTNVCLR-DTPHPSKERKNC---VTQLSNEV--SVTPAVCSPSKL
FSPAYKKLKRAPSSSPDLK-SHNR-GF------------PNRELQIKMTDGPCAGNASSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSQHHRLCALRVVRKDGENKGRQFYACPLPREAQCGFFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCDHGKRSIMRTV
LKIGPNNGRNFFVCPLGKEKQCSFFQWAENGPGIKILPGC-

----------------------------------MPEGPLVRKFHHLV--SQFVGQQVVK
TGGSSRKLQPASLQSLW--LQDAQVHGKKLFLRFDPDKEM--GPPG-----NSPPPE-PA
QKDAQ--EEGAADPRQAR---EPSGWKIPD-GSSR---SAE-LVPQGEGD-SQCL---AG
AAPA-EGAGRWLRVC--FG-LFGSIWVNEFSRAKKANKRGDWRDPAPR-------LVL--
-HFGSGGFLAFYNCQMSW--S-----SSPAVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 353)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQKHFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSASRREALVDGVVEFSATWLQ
GKLQGH--PQHTQVYQKEWCPAGHQLLKDAFGPPGGFQRLTWWCPQCQPQLSEE-LEQRQ
Y-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTS
VRGSA-------LRSLQ-------------------------G-RA-----L-PPAA---
-STAVVSR-QASALNN----N-DA----SS--------LFNGYVYSGVET----L----G
KELFMYFGPKAFRIH--FG-MKGSVMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQRRIGMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAENEVKKQKGRMLG
DVLLDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQTHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLAVSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICR
LPTRNTMISWTSGRVDH-VMGSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCVLCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKNEE-NSTVF-SHLMKYPCNTFRKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLEIK
KKQNQTLDEEFQNSPPTNVCLKD-TQNPSKKRTNN---ITQLSSKV--NISPTISSESKL
FSPAHKKLKTAHCSSPDLK-SCNP-GY------------SSSERQINMTD--------GP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGMKIIPGC-

----------------------------------MPEGPSVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EAPG-----SSPLAE-PP
QKEAQ--KEGAADPKQAG---EPSGQKTPD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPPGGFQRVTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGLLVRTFHHSV--SPFVGKQVVK
TGSNSKN-----LQSLW--LQDTQVHGKKLFLRFDPDEEM--GPAG-----NSSPPE-PP
QKEAQ--KEGTVD---------SNGQKTLD-ASSR---SAE----------LECL---KG
DTPT-GDAGRRLRVS--SC-LFGSVWVNDFSRAKKANKRGDWRDPAPR-------LVL--
-YFGGGSFLALYNCQMPW--S-----SSPEVTPTS------------LEAL--GQA

PF06831 // ENSGT00730000110955_0_Domain_1 (297, 353)

QPVS
YTPLNQKYFSGLGNVIKNEVLYRTGI--HPLSLGS--VLS----EALVDHVVEFSTAWLQ
GKFQGK--PQHMQVYQKEQCPAGHQVMKKPFGPSGGFQRLTWWCPQCQSQLLEEPEQ---
---------CQFF-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EAPG-----SSPPPE-PP
QKEAQ--KEGAVDPKQAG---EPSGQKTPD-GSSQ---SAE-LNPPGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--ALSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPPGGFQRVTWWCPQCQPQLSEE-PEQRQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SAFMGQQVVR
TGGSSKKLCPASLQSLW--LQDTQVHGKKLFLRFDADVDT--DEEVGAPG-SSPRPE-PL
QKRAR--REATVGPAPE-----PNAQNTCD-GSSL---SAG-LLPRGPGG-PDGL---VG
DSLT-AGAPRWLQVH--FG-LFGSVWVNDFSRAKKPNKRGDWRDPMPR-------LVL--
-HFGGGGFLAFYSCQMSWS-------LAPAIEPCRD

PF06831 // ENSGT00730000110955_0_Domain_1 (277, 354)

ILSEEFHRGQALEAL--GRPQPVC
YTLLDQRYFSGLGNIIKNEALYKARI--HPLSLGS--LLSASCLETLVEHVVEFSTDWLR
GKFQGQ--QRRTQVYQKEQCPAGHQVLKEAFGPPGGLQRLTWWCPQCQPRLPPEEPQQLQ
S-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SAFVGQQVVR
TGGSSKKLCPATLQSLW--LKDTQVQGKKLFLRFDA------DEEVGAPD-NSPLPQ-PG
QKGRR--RETAVGPAPA-----PSAQKACD-GSPQ---PME-LLP---------------
---G-AGAPRWLQVR--FG-LFGSVWVNEFSRAKKANKRGDWRDPVPR-------LVL--
-HFGRGGFLVFYNCQMSWS-------PAPTIEPRCDILSEEFHRGQALEAL--GR

PF06831 // ENSGT00730000110955_0_Domain_1 (296, 354)

PQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--LLSAPSLETLVDHVVEFSADWLQ
GKFQGQ--QQHTQVYQKEQCPAGHQVLKEAFGPPGGLQRLTWWCPQCQPRLPPEEPQQLQ
S-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MYFGPKALRIH--FG-MKGSIRINPLEDKNKS----G---VSPV-------FEVQL
T----KDLICFFDSSVELRNS-LESHQRIRRMEELDVCS

PF06831 // ENSGT00730000110955_0_Domain_1 (280, 353)

PKFSFSRAESEVKKQKGQMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQNHHLVKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 448)

NFSILFYR
CHKAGSAISTHYKVYKRPNCGLCCC--KITVCRLGKNNRMTYFCPHCQKENPQHV-DVSK
LPTRNTIIRWPPSRGAH-VMESVARKC

PF00641 // ENSGT00730000110955_0_Domain_2 (448, 475)

EEQWTCVVCTLINKPSSRACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PNDL--
-LHKSEE-NPITF-NNLVKFPCNNFGKSNKEVKLNRKTAFGTTTLVLTDFSNKSSSLERQ
KTKNQILDGEYQNSS-TNACFSD-TQQPSKERANY---ITQLSNKV--NISPMVCSQSEL
FSPAHKKLKTTQ-SSPDPE-SCNP-GF------------SNSELQVNMTDGTCTLNVGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCSKHNRLCVLRVVRKDGENKGRQFYACPLPREAQCGFFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSIMRTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGVKIIPEC-

----------------------------------MPEGPSVRKFHHLI--SPFVGQQVVR
TGGSSKKMPPATLQSLW--LQDTQVHGKKLFLRFNPNEEM--EPPG-----RNPPPE-PL
EGGAW--LEEAVCTEPVS---VPNAQETST-RPSG---SGE-PIPRGSDS-PDDL---GG
HSPA-AGAQKWLEVR--FG-LFGSIWVNEFSRAKKANKRGDWRDPVPR-------LVL--
-HFGGGGFLAFYNCQMSWS-------PPPVVEPTCDILSAEFHRGQALEAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 353)

-SRAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSSSRLVALVDHVVEFSVDWLR
DKFQGK--ERHTQIYQKDQCPAGHQVMKEMFGPPGGFQRLTWWCPQCQPQLPSEEYS---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------IHFG-MKGSIIINPHKYKNKN----E---MSPV-------FEVQL
T----KDLICFFDSSVELRNS-TESQQRIRMMGE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 348)

LDVCSPKFSFSRVESEVKKQKGRMLC
DVLMDQKVLPGVGNIIKNEALFDSGL--HPAVKXX--XXXXXXXXXX

ENSGT00730000110955_0_Linker_1_2 (348, 447)

XXXXXXXXXXXXX
CHKAHSAISTHYKVYKRPNCGQCYC--KITVCRLGENNRMTYFCSHCQKENPQHV-DISK
LPTRNTTVSWTSSRRDH-LLDLVAKK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

SEEQWTCVTCTLINKPSSEICDACLSPKP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

FDS--
-VLKNKE-NSVVF-TSLVKYPCNNFGKPSAEVKINQKTTFGTATLVLTDFSNKSNTLKRK
KSQNQILDGELQDS-PANICFSD-KLHPSVERRNH---VTQIPSRANINVSSVVDSQYKL
FNTTHKKLKTNHHSSLDIQ-SCNP-GF------------SSSELQRNMTDGTCTINAGA

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 700)

P
RCSKHNRLCILRVVRKDGENKARQFYACPLPQEAQCGFFE--------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------I--MPYLQVC--QLTDEQIHHLVKMIRDFTLLFYK
CRKTGSPLYKHYKVYRSRSCGQCNG--KITVCRLGENDRMTYFCSQCQNADPQLV-NVSK
LPARNSLIGWAYGRGSC-SNEHIAQ

PF00641 // ENSGT00730000110955_0_Domain_2 (446, 476)

KCEEEWTCMCCTLINKPSAEVCDACLTSRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

EGIER
LKTQNAG-DSAAFNTKLMKYPCNEFGKPSTEIKINRRAAFGTTTLVLTDLGNKVVL----
KNDNQISDGCSEYAAPESNCDQTHNNVYHSGRNMDKHSSTNVTA-----VASPSYQEPFS
LKPIKKKRKTHHVPS-VHQYDV---TS------------HYSKPQVNITDDN-RIKMGH

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
RCSKHSRLCSLRVVRKDGENKGRQFYTCPLPMETRCDYFQWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

HF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRCVMKTV
LKIGPNNGKNFFICPFGKEKQCSFFQWAENESAMQVIP---

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LTGHVYRGVET----L----G
KELFMYFDQKALRIH--FG-MNGSMRINPDGSKDRN----G---ALPV-------LEIQL
T----EDTICFFGVTTEYRKA-AESEQKVRMMESLDVCSPKFSFLRAESEIKQQKTRMLC
DV

PF06831 // ENSGT00730000110955_0_Domain_1 (303, 326)

LLDQTVLPGVGNIIKNEALFDSGL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCALCAERLRARLRRGQRVRA
ARGGG-------ASRAG-------------------------A-AG-----L-PRTG---
-LAAGA-PSGATAASK----ER---ISG

PF01149 // ENSGT00730000110955_0_Domain_0 (149, 247)

HD--------FLVGHVYRGVET----L----G
KELFMYFDQKALRIH--FG-MNGSMHINPDGSKDRN----G---AQPI-------LEIQL
M----E

ENSGT00730000110955_0_Linker_0_1 (247, 278)

DTVCFWDVTVEYRNA-AECEQKVRMMESLDV

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 351)

CSPKFSFSRAENEIKQQSTRMLC
DVLLDQTVLPGVGNIIKNEALFDSGL--HPALKVC--QLRDEHIRHLVKMTRDFTLLFYK
CRKTGSPLYRHYKVYKRPACRECSG--SITVCRLGDHNRMTYFCSRCQKADPQLV-NLSK
LPARNSLIGWAYGRGSC-SNEHVARKSEEEWTCMCCTLINKPSAEICDACLTSRPEVP--
-KMESFE-DSAAFNTNLMKYPCNDFRKPSTEIKINRKTAFGTTTLVLTDLGNKTVL----
RNYIQVSGGHSQCVFPKSNCKQIQSNACQSGGRKDKDCSTPVTA-----LPLSSCQQPVS
FKHIQKKQKTDHVPS-PVLLSHFV-TC------------HYSAPQSNVTDDTGMLSMGHP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 703)

RCTKHRRLCSLRVVRKDGENKGRQFYCCSLSRETRCEYFQWA

ENSGT00730000110955_0_Linker_3_4 (703, 707)

DLDF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRCVMKTV
LKIGPNNGKNFFVCPLVKEKQCGFFQWAENGPGMQILP---

----------------------------------MPEGPSLRKFHHLV--SPFVGQQVVK
TGGSSKKLCPAVLQSLW--LLDAQVHGKKLFLRFDPSEEL--EPPG-----SHLLPE-SL
QKGAE--KDDAVDPTLAS---GPSNEHTCA-GAAC---SLEPG-PSR-ASSAECP---GG
HSPA-AGAQTWLQVR--FG-LFGSVWVNNFSRAKKANKSGDWRDPVPR-------LVL--
-HFGGGGFLAFYSCQMSWS-------PPPELSPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 360)

LSEAFHRGQALEAL--GRAQPVC
YTLMDQRFFSGLGNIIKNEALYRAGI--HPLTPGA--LLTPSQLEALVDHVVQFSAEWLK
DKFQGT--RRHTQIYRKEQCPAGHQVLKEALGPPAGLQRLTWWCPQCQPPLPPEEPQ---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVEKGQSVVE
LRGSA-------VSGTV-------------------------S-SK-----H-PPPP---
-HHASISYCGRLNLSF----PL---ISHTS--------VKLGHHYVGLLT----A----G
YQTFSYYASGPLSVH--FG-MNGSIRLNQAVKKGQENSRPM---PVAV-------LEVQL
E----KDLICFYESTVDVRNV-SECQEKIRFLEE

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 360)

LDVCSSKFSFSRAECEIKKQKARMLC
DILLDQMILPGVGNIIKNEALFDSGL--HPGVQVCAGLLTDMQVSHLVKMTRDFTLLFY

ENSGT00730000110955_0_Linker_1_2 (360, 447)

K
CRKSGSALYKHYKVYKRPNCGQCDK--KITVCRLGENNRMTYFCPKCQNDKPQHV-DVSK
LPKRNSLIGWVQRIPPH-SNEHVATS

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 476)

KEEHWACTVCTLINKPSDKQCDACLTQRP

ENSGT00730000110955_0_Linker_2_3 (476, 660)

EVS--
-SLAESD-KAAELDADLVKYPCNNFAKLLPELKLNRRTAFGNTTLVLTDFGAKEDLSDKN
--IQQHSLNSSTFDVPLSKHFNGKNSSNK--RSNENEHWTNTLNA--LNG--GSGTSNNV
FNHPQKKLKTVHQTPNKTNIRSTISNL------------RCSSSQSTMARD-AATNTGG

PF06839 // ENSGT00730000110955_0_Domain_3 (660, 705)

P
NCSTHNVPCALQVVRKEGENKGRSFYTCSLPRERCCQFFEWADL

ENSGT00730000110955_0_Linker_3_4 (705, 707)

HF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 751)

PFCNHGKRCIVRTV
LKLGPNNGKNFYVCPMGKDKQCNFFEWAKRGPGVSNAIAST

----------------------------------MPEGPSVRKFHHLV--SPFVGQQVVK
TGGSSKKLNPASFQSLW--LLDNQVHGKKLFLRFDPDEEL--GSLG-----NNSLPE-PL
QEGEK--KEEAEDQKQAL---GPSSREINR--SSQ---SLERVVPSGDNG-LECL---RG
DTPA-EGAERWLQVS--FG-LFGSIWMNEFSRAKKANKRGDWRDPIPR-------LVL--
-YFGGGGFLAFYNCQMAWS-------PSPVVIPA

PF06831 // ENSGT00730000110955_0_Domain_1 (275, 353)

SDILSEKFHRARALEAL--SQEQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPPHLEALVDHVVEFSADWLR
GKFQGK--QQHTQVYQKEQCPVGHQVMKEAFGPPGGFQRLTWWCPQCQPRLPPDEQEQGR
L----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

-----------------------------MTQGGM

PF01149 // ENSGT00730000110955_0_Domain_0 (36, 248)

PEGPSVRKFHRLV--TPFVGQQVAK
TGGSSRKLCPADLQALW--LRDVQVHGKKLFLRFDTGDET--GRPG-----NSPLPE-PL
QKEEA--GTWELGG-----------QEIPV-LPPG---AAVRV-AAG----SEGE---GA
DAS-AGHAERWLQVG--FG-LFGSVWVNEFSRAKKANKRGDWRDPVPR-------LVL--
-YFGDGG

ENSGT00730000110955_0_Linker_0_1 (248, 293)

FLALYNCQMSWR-------PHPVVRPACDILSEKFHRGQALQAL-

PF06831 // ENSGT00730000110955_0_Domain_1 (293, 353)

-GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--LLSPARLESLVDQVVEFSAGWLQ
GKFRGQ--RQHPQIYQKERCPAGHQAVRAALGPPGGFQRLTWWCPQCQPRLPPEEPGSLL
P----------------------------------------PGPGAPPGIVASGELDA--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MVEGPGCTLNGEKIRARVLPGQAVTG
VRGSA-------LRSLQ-------------------------G-RA-----L-RLAA---
-STVVVSP-QAAALN-----N-DSSQNVLS--------LFNGYVYSGVET----L----G
KELFMYFGPKALRIH--FG-MKGFIMINPLEYKYKN----G---ASPV-------LEVQL
T----KDLICFFDSSVELRNS-MESQQRIRMMKELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPEFSFLRAESEVKKQKGRMLG
DVLMDQNVLPGVGNIIKNEALFDSGL--HPAVKVC--QLTDEQIHHLMKMIR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CRKAGLALSKHYKVYKRPNCGQCHC--RITVCRFGDNNRMTYFCPHCQKENPQHV-DICK
LPTRNTIISWTSSRVDH-VMDSVARK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEHWTCVVCTLINKPSSKACDACLTSR

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PIDS--
-VLKSEE-NSTVF-SHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERK
TKQNQILDEEFQNSPPASVCLND-IQHPSKKTTND---ITQPSSKV--NISPTISSESKL
FSPAHKKPKTAQYSSPELK-SCNP-GY------------SNSELQINMTDGPRTLNPDSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCSKHNRLCILRVVGKDGENKGRQFYACPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PFCNHGKRSTMKTV
LKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC-

----------------------------------MVEGPGCALNGEKIRARVRPGQAVAA
VRGRA-------LQSRP-------------------------G-PV-----P-PPAA---
-PAAEGAF-QAAALQD----SKDPSQNFLR--------LFNGYVYSGVET----L----G
KELFMFFGPRALRIH--FG-MNGSIRINPLPYKNKN----E---ISPV-------FELQL
T----SDLICFFDSSVELRNS-TEIQQRIRRMEELDVC

PF06831 // ENSGT00730000110955_0_Domain_1 (279, 353)

SPKFSFLRAESEVKKQRGRMLC
DVLLDQKVLPGVGNIIKTEALFDSGL--HPAVKVF--QLTDEQTHHLVKMVR

ENSGT00730000110955_0_Linker_1_2 (353, 447)

DFSILFYR
CCKTGSAISKHYKIYKRPNCGQCRC--KVTVCRLGENNRMTYFCPRCQKENPQHM-DICK
LPTRNLMISWTSSRRDH-LTDSVSRK

PF00641 // ENSGT00730000110955_0_Domain_2 (447, 475)

SEEQWTCLVCTLVNKPSAETCDACSTSK

ENSGT00730000110955_0_Linker_2_3 (475, 661)

PVDS--
-VFKNEE-NSVVF-DNLVKYPCNSFGKVHTEVKINKKTVFGTTTLVLTDFSNKSSTLKRK
ESQTQTPDGEFQNSLPTNVCFSD-TRHPSKERTNY---ITQVSNKV--NISPTVCSQSEL
FSSAHKKLKTTHYPTPDRK-SCNT-GF------------SNSELQTSTTVGPCTLNAGSP

PF06839 // ENSGT00730000110955_0_Domain_3 (661, 704)

RCRKHNRLCVLRVVKKSGENKGRQFYTCPLPREAQCGFFEWAD

ENSGT00730000110955_0_Linker_3_4 (704, 707)

LSF

PF06839 // ENSGT00730000110955_0_Domain_4 (707, 750)

PLCNHGKRSIMRTV
LKTGPNNGKNFFVCPLEKEKQCNFFQWAENGSGMKIIPGC-

----------------------------------MPEGPLVRKFHHLI--SPFVGQQVVK
TGGSSKKLQPAGLQSLW--LQDTQVHGKKLFLRFDPDEEM--EPPG-----SSPPPE-PP
QKEAH--KEGAVDPKQDG---EPSGQKTLD-GSSQ---SAE-LNPQGEDE-SECL---EG
DAPA-GDAGRWLRVS--FG-LFGSVWVNEFSRAKKANKRGDWRDPSPR-------LVL--
-YFGGGGFLAFYNCQMSW--S-----SSPVVTPAC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 354)

DILSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEVLYRAGI--HPLSLGS--VLSAPRREALVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKDQCPAGHQVMKEAFGPPGGFRRLTWWCPQCQPQLSEE-PERRQ
V-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPSVRKFHHLV--SPFVGQKVIK
TGGSSRKVYPATFQSLW--LQDAQVHGKKLFLRFDPDEEM--EPLN-----SSPQP----
VQGMW--QKEAVDPELGL---GSSAQEPSA-GPSG---SGEPV-PSRSDE-TFDL---GG
KIPS-AGARKWLEVR--FG-LFGSIWVNDFSRAKKANKKGDWRDPVPR-------LVL--
-HFSGSGFLVFYNCQMSWS-------PPPVIEPTC

PF06831 // ENSGT00730000110955_0_Domain_1 (276, 355)

DILSEKFHRGQALEAL--SQAQPVC
YTLLDQRYFSGLGNIIKNEALYRARI--HPLSLGS--SLSSFSREALVDHVVEFSKDWLQ
DKFQGK--ERHTQIYQKERCPSGHQVMKETFGPPDGLQRLTWWCPQCQPQLSSEGPQTLP
S----------------------------------------S------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------MPEGPLVRKFHHLV--SPFVGQQVVK
TGGSSKKLQPASLQSLW--LQDTQVHGKKLFLRFDLDEEM--GPPG-----SSPTPE-PP
QKEVQ--KEGAADPKQVG---EPSGQKTLD-GSSR---SAE-LVPQGEDD-SEYL---ER
DAPA-GDAGRWLRVS--FG-LFGSVWVNDFSRAKKANKRGDWRDPSPR-------LVL--
-HFGGGGFLAFYNCQLSW--S-----SSPVVTPTCDI

PF06831 // ENSGT00730000110955_0_Domain_1 (278, 354)

LSEKFHRGQALEAL--GQAQPVC
YTLLDQRYFSGLGNIIKNEALYRAGI--HPLSLGS--VLSASRREVLVDHVVEFSTAWLQ
GKFQGR--PQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEE-PEQCQ
F-S---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------