ENSGT00730000110953_1 : Linker Region Query Results

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------------------------------------------MEGCLGEESFQMWELNRR
LEIYL-SRVKALEEQNELLSAELGGLRAQ-SADASWRARANDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEAV--AGRCQQQRLAREQAADEAARSRRAVEAEKCAQTWLST
QAADLEREVE----ALRAAHEEERACLNAQAAC---------------------EVE-EL
AQRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQNQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENTRLQTSGSGPKTSLGFQ---------------------------
--------------------------------------------------DPKPELHFPG
TPEGRRLGHLLPVLSPTPLTSPLPDTLRTPMPALPKRQEFLQACT--PTLASTPISPTPQ
APCPATDTQIRTREAPLTLLQSQGG-KQQAPEPLWAEAKV-AIPASILAGPEEPGGKQQE
ASPGQSPEDDVSLAPP--PN----PDHPSLEAKDGEPS-------------GSGKSSVSQ
EEGKGQTWGLTEEEA----TIEVKVGSSLQKETWQEEGDVDREEIQEPQ--SLLEKETPK
SLEEEIQEPLMSLEKQGHETLRSLEKESQDSLGSLEEENLETP-KTLEKENQELLKTLEE
KGL-EVVRAVEKETLELLTPVEKEDPQTLQSLEKENQERLRSLDDNLETFLFPGKENQE-
LVRSL--EEGNL---------------------ESLRGLEKESQEPLRSQGVEDEEA---
------------------------------------------------------------
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-------------------------------LRHLAKENQEPLRSQEVEDQETLRPLEKE
NEE----------------------PLRSLKNENQ-------------------------
---------------------------ETLKPLEKENQESLKSLED--------------
--------------------------------------------ENQEA---LENMDQEQ
LGSQ--------E---------------------EE----------------------NQ
KTLSSLEKETQEPLG----------------------SLGEEDQKTLK------------
----------PLEK-DNQELLGSLKEDSVEAVKSLEIGNLESLKSAEEKVLGILKLPETQ
EPLRPLEEKNQETTNALEKE-IQEPLGS-------VEETQEILKPLEKEHQEPLRSLGEW
DLENLKSSEEVDKESQRYLEEEGNLEKG--ENKDSLRSLEEEGQELPLSANQQRWEEVVV
GDQEL---NQDPQPGKDEVENENEAEL-GLREQDGLHGKEEIEGQVELRLNA-AGETWNT
GSGHPGSPEPEEQRI---PVEGAEGEGGAEG-----LQDPEGQPDHMGAPGLR--APQGM
PEVVAPMFKDEDVAPGGDPASLQ---VTLGSETAMGES---AVGAE--------------
--ERLEQEAVRLEDPGPL---AREEV-TKPPLGKEDLEAKKVQGLEEPRRDLKEADALES
EVSKLPRE---STDPQKPEESEGWEESESEAAWGTEEG--LPADIL-------CLNG---
------INASQPRPE------EDTKPVLGPASPR----PTEPWVPTSLPEDAPGPQ----
TEGNQEA--SWGLEGSAEGQGKLEGEQ-EM-GSGGIPEG-LQEEG-----EESGEESEAD
ELGETLPDSTPLVLFPGSS-----ASSKWGPAEEERPFPQ--GEARQESWDPTL-QSSEG
----------LEAQPSEEDNR--------DEEEGHSHDSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLRQVPQVL------LEPA-AWDRDEESDGFA--------
------------------GAGQWGAGSSMGSLQTLGGLQRGDLVESE--TTSVS------
---------APMTALE----------TKSQDSAEPSCSEE--------------------
--------------------------------------------ESDLVPLERE-DKVS-
-GPLETPSEVEDTGHQGAGETFGVNGQGPSWEE---ESEHLNGGLVTRLEQPEGGGQGKP
GAPEGDQGSPLEV--EEGGSLKAPWPGVPLRLGQGQFLQFTQK--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELRGHRAQ-SGDSSWRGRADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTAEEAARNRRAVEAEKCAQAWLRT
QAAELERELE----ALRAAHEEERAGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMEMSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLQATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGVSKASLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGPLLPVLSPTSLPSPLPATLETPVPTFLKSQEFLQART--PTLASTPIPPTPQ
APCPATDTEIRPQDTPLSLLQPQGG-KQQAPESLWAEAKV-GIPASVLPGPEEPGGKQQE
AGTGRSPKDQASLAPS--LS----PDNSSLEAKYGEPR-------------GSRVSSMFQ
EESEGQILGLVEKET----AIEGKVVNSLQQEIWQEEGDLDMKETQDYQ--VPLEKESPK
LLAEEIQEPMMSLENQSHET---LEKENQECPRSLE-ENLETL-KSLEKENQELTKSLEE
KDI-KVVKPLEKEALELLKPIGKDDIETLKSPEKENQELIRSLEGDIETFLSPGKENQE-
LVSSL--E-ENL---------------------QSLTALEKENQEPL-------------
------------------------------------------------------------
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-------------------------------------------RSQEVEDQETLRPIMRE
NQE----------------------SLRSPEDENQE----------------------TF
RPLEKENQEQLSSLGE--------EDQKIIRPLEKENQESLR------------------
------------------------------------------------------------
--SL--------E---------------------EE----------------------DQ
ETLRPLEKETQQSPR----------------------SLQEEDQMTLRPPEKVDPELLKS
LGKDQEIT-RPLEK-ENQELLKSLEEESVEAVRYLETENLESQKCA-EENPEISKSLETQ
EPLWSLEEMNQGTMKTIEND-TQEPLGS-------VEENQETMRLLEKKNQEPLRSLGAQ
DLENLRSPEEVDKESQKNLQEEENLEKE--ENQESLKSLEEEGQELPQSADQQRWEDMVV
RDQEL---SQESPPGRAGVENEEEAEL-DQRVQDGFSGEEEAAEQTELQLNA-TGEAWSP
GEGHTGSPEAKEQRG---PAAGASGKGGAEG-----LQDLEGQPEQGVAPGLQ--ASQGM
PEVTEPLLEDEDAVPGGDQASPE---VTLGSEPAMGES---AVGAE--------------
--QELEQEVLGPEDAGHL---ARK-V-MEPPLGEESLEAKRVQGLEGPGKDLEEADALEA
ELSKLPRK---SRDPLEPPK--GWEESELEAPWGAEEA--FPAEIS-------GHHG---
------SEATQPRPLGSEEAEGDIQTVLG----------------PPILEDAPGPQP--Q
AEGSQEA--SWGLEGRAEALGEVEGEQEEL-GSGEISEG-LQEEE----EEESKEESEAD
ELGETLPDSTPLGLYLRSP-----TSSQWDPAGEQGPSPQ--GETREEGWDPVV-LASGG
----------LGGQPSEEEEEE-------DGEEECGHDSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLGQVPQLV------LEPA-AWDRDGESDGFADEEESGEE
AEE------DEEEEGREPGAGQWGPGSSVGSFQALSSSQRGNLQESE--TMGVSV-PWD-
DGLRGVVAGASVATQG----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVPLETE-DQEP-
-GLLETPSEVEDMGP-GAGDTCGVNGQGPSLEE---ESEHMNGGVLNGLEQSEGVGQGKL
GAPERDRGSPLQE--EEGGALKTPWAGAPLHLGPGQFLKFTQR--EGDQDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLGAELRGHRTK-SADTSWRARAHDELAALRALV---DQRWRE
KHAAEVA---RDNLVDELEGV--AARCQQLRLARERTAAEAASYRRAIEGEKCAQSWLST
QAAELARELE----AMRAAHEEERASLNAQ AACAPRCP-VPP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMEVSLVQARERLGRAVQGACEGRLELQQLQAERGGLQ
ERRTALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGNVPKASLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGPLLPVLSPSSLPSLSPATLETPVPAFLKSQEFLQART--PALASTPIPPMPQ
APCPAADPEIRAQDAPLSLLQPQDG-KQQAPEALWAEAKV-AVPVSVLPEPEEPGGKQQE
ASPGQSPKDQASLAPP--LS----PDNSSLEVKGVEPR-------------ASRVPSIFQ
EEGEGQIWGLVEKDT----ARESKMVSSLQQEIWQKEGDLDMKETQDSQ--VPLEKETLK
LLGEEIEEA---LENQSHET---LEKENQESLRSLE-GDLVIL-KSLEKEN---------
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---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SADTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTTEEVARNRRAVEAEKCARARRGS
QAAELERELE----ALRVAHEEERVGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSPAADAEIRAQDAPLSLLQTQGG-RKQAPEPLRAETRV-AIPASVLPGPEEPGGQRQE
ASTGQSPEDHASLAPP--LS----PDHSSLEAKDGESG-------------GSRVFSICQ
GEGEGQIWGLVEKET----AIEGKVVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQECPRSLE-GDLEEL-KSLEKENKELLK----
-DV-EVVRPLEEEAVGQLKPTGKEDTQTLQSLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEAGDEEALRPLTKE
NQE----------------------PLRSLEDENKE----------------------AF
RALEKENQEPLKTL----------------------------------------------
------------------------------------------EEEDHSIVRPLETENHKS
LRSL--------E---------------------EQ----------------------DQ
ETLRTLEKETQQRRR----------------------SLGEEDQMTLRPPEKVDPEPLKS
L--DQEIA-RPLEN-ENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQ
TPLWTPEKINQGTMKPLEKE-IQEPLES-------VEVNQETLRLLEEENQESLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--EYQESLRSLEEEGQELPQSADVQRWEDTVE
KDQEL---AQESPPGMAGVENEDEAEL-NLREQDGVTGKEEVVEQGE--LNA-TEEVWIP
GEGHPESPEPKEQRG---LVEGASVKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLVED-DVAPGGDQASPE---VMLGSEPAMGES---AAGAE--------------
--PGPGQGLGGLEDPGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGT
EFSELPGK---SRDPWEPPK-GG-EESEAEAPRGAEEA--FPAETL-------GHTG---
------SDAPPPWPLGSEEAEEDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPEG-LQEEG-----EESREESEED
ELGETLPDSTPLGFYLRSP-----TSPRWDPTGEQRPPPQ--GETGKEGWDPAV-LASEG
----------LEAPPSEKEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------PLLPGVPGE--VAEPLGQVPQLL------LDPA-AWDRDGESDGFADEEESGEE
GE-------EDQEEGREPGAGRWGPGSSVGSLQALSSSQREEFLESD--SVSVSV-PWD-
DSLRGAVAGAPKTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEIPSGMEDAGP-GA-DIIGVNGQGPNLEG---KSQHVNGGVMNGLEQSEEVGQGMP
LVSEGDRGNPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SADTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTTEEVARNRRAVEAEKCARAWLSS
QAAELERELE----ALRVAHEEERVGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEDRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSPAADAEIRAQDAPLSLLQTQGG-RKQAPEPLRAEARV-AIPASVLPGPEEPGGQQQE
ASTGQSPEDHASLAPP--LS----PDHSSLEAKDGESG-------------GSRVFSICQ
GEGEGQIWGLVEKET----AIEGKVVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQECPRSLE-EDLETL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVGDEEALRPLTKE
NQE----------------------PLRSLEDENKD----------------------AF
RSLEKENQEPLKTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHKS
LRSL--------E---------------------EQ----------------------DQ
ETLRTLEKETQQRRR----------------------SLGEEDQMTLRPPEKVDPEPLKS
L--DQEIA-RPLEN-ENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQ
APLWTPEEINQGTMKPLEKE-IQEPLES-------VEVNQETLRLLEEENQESLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--EYQESLRSLEEEGQELPQSADVQRWEDTVE
KDQEL---AQESPPGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--LNA-TEEVWIP
GEGHPESPEPKEQRG---LVEGASVKGGAEG-----LQDPEGQSQQVVAPGLQ--APQGL
PEAIEPLVED-DVAPGGDQASPE---VMLGSEPAMGES---AAGAE--------------
--PGPGQGVGGLEDPGHL---TRGEV-MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGT
EFSELPGK---SRDPWEPPK--GREESEAEAPRGAEEA--FPAETL-------GHTG---
------SDAPSPWPLGSEEAEEDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPEG-LQEEG-----EESREESEED
ELGETLPDSTPLGFYLRSP-----TSPRWDPTGEQRPPPQ--GETGKEGWDPAV-LASEG
----------LEAPPSEKEEGE-------EGEEECGRDSDMSE-EFED-LGTEA------
------PFLPGVPGE--VAEPLGQVPQLL------LDPA-AWDRDGESDGFADEEESGEE
GE-------EDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESD--SVSVSV-PWD-
DSLRGAVAGAPKTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEIPSGMEDAGP-GA-DIIGVNGQGPNLEG---KSQHVNGGVMNGLEQSEEVGQGMP
LVSEGDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SADTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTTEEVARNRRAVEAEKCARAWLSS
QAAELERELE----ALRVAHEEERVGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSPAADAEIRAQDAPLSLLQTQGG-RKQASEPLRAEARV-AIPASVLPGPEEPGGQRQE
ASTGQSPEDHASLAPP--LS----PDHSSLEAKDGESG-------------GSRVFSICQ
GEGEGQIWGLVEKET----AIEGKVVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQECPRSLE-EDLETL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGQLKPIGKEDTQTLQSLQKENQELMKSLEGKLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
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-------------------------------------------RSPEVGDEEALRPLTKE
NQE----------------------PLRSLEDENQE----------------------AL
RSLEKENQEPLKTLEE--------ED----------------------------------
----------------------------------QSIPLKTLEEEDQSIVRPLETENHKS
LRSL--------E---------------------EQ----------------------DQ
VSLRTLEKETQQRQR----------------------SLGEEDQMTLRPPEKVDPEPLKS
L--DQEIA-RPLEN-ENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQ
APLWSPEEINQGTMKPPEKE-IQEPLES-------VEVNQETLRLLEEENQESLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQELLRSLEEEGRELPQSADVQRWEDTVG
KDQEL---AQESPPGMAGVENEDEAEL-NLKEQDGFTGKEEVVELGE--LNA-TEEVWIP
GEGHPESPEPKEQRG---LVEGASGKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLVEDEDVAPGGDQASPE---VMLGSETATGES---AAGAE--------------
--PGPGQEVGGLEDPGHL---TREEG-MESPLEEESVEAKRVQGLEGPRKDLEEAGGLGT
EFSELPGK---SRDPWEPPK-G-REESEAEAPRGAEEV--FPAETL-------GHAG---
------SDAPPPRPLGSEEAEEDVPPVLVPPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPEG-LQEEG-----EECREESEED
ELGETLPDSTPLGLYLRSP-----TSPTWDPTGEQRPPPQ--GETGKEGWDPAV-LASEG
----------LEAPPSEEEERE-------EGEEECGRGSDLSE-EFED-LGTEA------
------PFLPGVPGE--VAEPLGQVPQML------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEEGREPGAERWGPGSSVGSLQALSSSQRGEFLESD--SVSVSV-PWD-
DSLRGAVADAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEIPSGMEDAGP-GA-DITGVNGQGPNLE----KSQHVNGGVMNGLEQSEEVRQGMP
PVSEGDRGSPFQE--EEGSALKTSWAGAPVHLGQSQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQMWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADDELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELESV--AGRCQQVRLARERTIEEAACSRRALEAEKNARGWLST
QAAELERELE----ALRAAHEEERAHLNAQAACTPRRPPAPA---HVS-PVRAPEVE-EL
ARRLGEVWRGAVRD--YQERVAHMESSLGQARERLGQAVRGARESRLEVQQLQADRDSLQ
ERREALEQRLEGRW--QDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRSSQASLGFP---------------------------
--------------------------------------------------DPKLKLHFLG
IPEDQHLGSVLPVLSPTSFSSPLPNTLETPVTAFLKTQEFLKART--PTLASTPIPPMSE
APYPK-NAEVRAQDVPHSLLQTQGG-RQQAPEPLWAEATV-PSSTGVLPELEEPGGEQ--
--PDHFPDDPTSLAPP---L---NPHHSILEAKDRESS-------------ESRVSSIF-
QEEEGQIWELVKKEA----ATEVKVENSLAQEIQES--GLDTEEIQDSQ--GPLQKETLE
ALGD---EPLMSLKTQNHET---PGKENCNS--SIEE-NSGTV-KSPEKEKQTPLKSLEE
KNV-EAEKTLENGVLELSKPLGEEEP------RMEDQEL-MSPEHTLETVSFLGKENQE-
VVRS-SEEQNLESLITFKEESQYPLGGPEAEDQMLERLVEKDDQRFPRSPEE-DQQAFRP
LEKENQEPLRFEEAEDQVLERLIEKERQESLKSPEEEDQQAFRLLEKESQEPLRFEEAED
QVLERLVEKESQESLK--------------------------------------------
--------------------------------------------SLEDEDQQAFRSLEKE
KQEPLRFEEAEDQVLERLIEKERQESLKSPEEEDQRTGKPLEKENQESLRSLDE-NQETI
VLLESRNQRPLRSLEV------EEEEQRIVKPLEKVSQVSLESLEKENVQSPRYLEEDDH
--MIKSLLEDKTHEILGSLEDRNGENFI-PPENETQGSLRPPEEEDQRIVNHLEKESQEF
LRSPEAE---EEEEQVMVRSLEGENHDPLSSVVKEEQMA-ESKLENESQDSGKFLEDESQ
ETFGSLEKENLESLRSLAGQDQEEQK-LEQETQQPLRAVED-EQMTVNPPEKVDPGLPKP
LRNDQEVV-RSLDK-ENQESLVSLNEGDMETVKSSETENIESLETV-GECLGRRKSADTQ
EPLWSTE-VTSETIEPLEDE-TQEPLGC-------VGENQEVLTPLERESQE-LRSLGKW
NLETVESPGGVED-SQQCLEVEEGPERE--QHQESLRSLGEVEWELPGSGSQQRWEDVV-
EDGEV---GQEASPGATGVETEDKAEL-HLR---GQGGEEKAVEEKELLQDA-VGEAWSL
G-----SSEPKEQRV---PAE---------P-----LDDLEGQPEQTGALEVP--VAQGM
PEAAE---QDEDRAQAGEQDSVE---VTLGLEA-ARAG----------------------
--LELEQEVVGLEDPRHF---AREEA-IHPSLGEESVKAKIDQGLEEPGKEPKEAGALDS
GIPELPKT---SSETLECK---GWEE--SGEGWGEEEA--S-LETS-------DHEG---
------SHAPQPRPPKTEED-EGVQAALTVSGPK----LLEPCSPIPILTDAHELQP--Q
AEGIQEA--GWQPEAGTEALGRVEDEP-EF-GRGEIPEG-LQDWE------EGREDSEAD
ELGETLPDSTPLGLYLKSP-----ASPKWEQAGEQRLFPQ--GEARKEGWSPAV-LAAQG
----------LSDPPEE---------------EQQGHDSDLSSEEFED-LGTEA------
------SLLPGVPKE--VSDHLGQEPPV-------LQPA-CWDQGGESDGFADEEESGEE
GEEED----ADEEEGAESGAQWWGPGPSGGGVKVQDVTQRGDL-EHE--SVGDSG-LWD-
DGLSGAAANVLVTALE----------TVSQDSAEPSGSE---------------------
--------------------------------------------GSESASLEGEEGQAI-
-DHLDAPQE---VVP-GAGDTFDISGQGPNLE-----SEQVNGRMENGVEQAEGQVVL--
-DGDEDQGIPLQE--Q--GTLKAPLVGSPVHLGPSQPLKFTLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQLWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADDELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELEGV--AGRCQQVRLARERTSEEAACSRRALEAEKSAQGWLSS
RVAELEREVE----AVRAAHEEERAHLNAQAACAPRRLPVPP---RGP-PARVPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMESSLGQARERLGRAVRGAREGRLELQQLQAERDGLL
ERREALEQRLEGRW--QDRLQATEKFQLAVDALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRGSQASLGFQGKRRSQLLLEVPPFTLKIPFLSSTNQS
KSLLCGSNHTDVPSLASGGQRKWLVYSGQGEGCSVVRSGHTYSVSYSALPDPKLKLHFLG
TPEDQHLGSVLPVLSPTPLPSPLPDTLETPVTPFLKTQEFLQAQT--PTLASTPIPPMTE
APFPT-KAEVRAQDVPLSLLQTQGG-RHQAPEPLWSEATA-PVSTGVLEQLEEAGGKM--
--EETLPFIGKENEEV--MRSSEEKNLESLTAFKKESQP----PLGCPEEEVQRVERLIE
KEGQESLRSLEEEDQETYRPLEKENGEPLKSVEEEV--QLVERLIE--------------
KEGQ---ESLRSLEEEDQETYRPLEKENGEPLKSVEE-ELQLVERLIEKEGQESLGSLEE
EDQ-ETYRSLEKEEDQLVER------------------L-IEK-EGQESLRFLEEEEQE-
TYRPLEKEEDQETYRPLEKENGEPLKSVEEEVQLVERLIEKEGQESLGSLEEEDQ-----
---------------------------------------ETYRPLEKEDQK---------
--VERLIEK---------------------------------------------------
-------------------------------------EDQESLSCLEEEEQETYRPLEK-
---------EDDQKFERLIEKGDQESLTCLEEEDQRIVKLLERENQESLRSLDE-NQDTI
MPLESKTQKPLKSLEV------E-EEQRIVKPLEKVSQGSIGSLEKENVELLGSLEDNDQ
--MTESLLKKGTQESLGSHEDTNQE---------TQDPQRFLEEEGQGIVKQLEKENQSF
LGSL------EE-EQVVKRSLERENHEPLSSVEKKDQMT-KSLLEKESQDSGKSLEE-DQ
EAFRSLGKEDPESLQSLEEQDQEIQRYLQQETQQILGTLGS-AQMASKLPENVGPELLKS
LGNDQEIV-RSLEE-QNQESLVSLKETSVETVKSSEIENTEPLKNA-EEDLEIINSIEAQ
ESLWSTE-VTRETTKPLEKE-IQESLGF-------VDGNQEMLRPLDRENQE-LRSLGKW
HLETVDSSEGMEE-GRQRLEVEAVLETE--EHQELLGSLEEGEQGLPGCVNQQGWEDMAV
EHAAA---DQGPTLGRAGVESEDEAEL-PLS---GQGEKKEGAEERERQLDA-MGEAWSL
E-----ISEPQEQRV---PSEEG----SPGA-----LQDLEGQPEQVGALEVP--VGEGI
PEVTEPLLQDEDIAQTGEQDSIE---VTLGSENATRAE----------------------
--LVLEQEVVGLGGPTHL---AREEA-NHPSLGEESVEAKIAQDLEGSGKEPTEAGALES
ESSELPRA---SSDTLESK---GCRESEPVVGWAVEEA--S-VETS-------DHEG---
------SGSPQPRPSETEGD-EGTQAALAPPDPK----LVEPCSPTPILEDACEQQP--Q
ADGIQEA--GWQLEGGSEALERVEDEQ-EF-GLGEIPEG-LQDWE------ESREESEAD
ELGETLPDSTPLGLYLRSP-----TSPKWDLAGEQRLSPQ--GEARKEGWGPAV------
----------LSNPSGE---------------EEQGHDSDLSSEEFED-LGTEV------
------SLLPGLPKE---------VPPV-------PEPE-CWDQGGESDGFADEEESGEE
GE-----------EGTESGAQWWGPGSSGGGFKVQHITQRGDLLEHE--SVGVSG-PWD-
DDLRGATANISVTGLE----------TESQDSAEPSGSE---------------------
--------------------------------------------GSESVSSEGE-DQVP-
-DHLGAPQGVTNMVP-VGGDTFGISGQGPRLE-----SEHMNGRMENGLEQSEGQGVL--
-DGHQDQEYPSQE--QEVGALKAPLVGSAVHQGPSQSLEFPLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQLWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-AS-DSWRARADDELAALRALV---DQRWRE
KYAAEVA---RDNLAEELEGV--AGRCQQLRLARERTAEEVARSRRTFEAEKCARGWLSS
QVAELERELE----ALRAAHEEERANLNARATCVPRGP-APP---RAP-PAPAPEVE-EL
AQRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGVRDSRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATENFQLAVEALEQEKQGLQSQIAQILEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTSGCNSKVPLSFH---------------------------
--------------------------------------------------DPKLELHFLG
TPDSRRVGPVLPVLSPAPLPSPLPDSLETPVPAFLKNQEFLQPRA--PTLASTPIPPVLQ
PPCAASKTELRAPEGPVSTLPPQDG-RQQAAQPLWAEAKT-SSPGNILPGPEEPGGEQPE
PSSSQVPENQT---LP--LS----PEQPSSDAKDREPS-------------GSRVDSIFQ
EEEEGHLAGLLEEET----AMEVKVASKLQQETEQDG-ALAMEEIEDSQ--SPLDKASPK
ALGEEILKPWVPLASQSQQV---LEQENQEPLRSLEEGSLDTL-DSPKAESSEPLEHRGE
KDP-EAEGLMGEERPALLQAAWKEDPQTLPCPAMEDQGLIVSLDSNLETLKFPGKENGE-
LVPSP--KEEEVE---------------------VPRTAEDGTWEPLRPEEAQDQQARMA
PREETGESLGSSED----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------ENPEVLRPLGKEEQGALGALEEEGQKIV--------
-----TALE---------------------------------------------RELQEP
LRLG--------E---------------------EE----------------------DQ
EVLRGLENETLQSWR----------------------AL----AETLTPVEKVGPEPLPC
PSADQEEV-RPEEE--ITEFSESQEDEFAKARESSEPEDLEPPKLA-EEGLQVQKSP--E
VPLWSLEATP---------L-ALEPLGP-------VEGHPEALQTLKDRDQETLRSPGEG
CPEEE----EEDEESQRDVAGVEEEEKAEKQVETPLRQLAEEWQKPSPSADEQKWGNVLE
EGQDP---SHECPGEPAGVSGEEEAEL-DPRQPEGSAGQEEAVMSAELQLHA-AEL----
VAEQPGSPEPREQSV---LARTACGMGGTEG-----LQDPEGQVEHLGAPGLR--APQAI
AEATESLWEDD-------QLSPE---VTLESEIATGESAE--------------------
---GTEQADMGLDSLDHL---AREEV-MQPSSGEESLEARRVPGLEAPAQHLQEADALQA
KPSPLGAS---REPPKSPEE--GLKASEPPMLWTAEEE--APANTL-------DHNA---
---------PESRPLESEAAEE-DPLALGPSLM-----------CPPIPEGAYETPP--Q
AEGNQMV--SWGL-------GKVQVEQEDL-DSGEISES-LQEEG-----EESREGSEAD
ELGETLPDSTPLGLYLGSP-----SSPRWGLAGEQRPSPQ--GEAREEGWDTAA-PASEG
----------LEAQPSGKEEEE-------DGEEEHDRGSDLSE-EFED-LGTQV------
------SLLPGLPRE--AAAPPGQVPQL-------LEAA-IWNPDGESDGFADEEESGEE
GEE------EEKEEGRKPGAGQWEPGSPPGSLQALHSPPRGDFLESESETVGVSI-PQDD
DGLRGAKAKA----------------PKSQDSAEPSGSEE--------------------
--------------------------------------------ESDSAPWAGE-DQVP-
---METPGG-DDTSP-GTGDTLAINGQGPNMM-----SEQVNGGVVNGLQRPAGVGQA--
--PAGDRGSPIAEEEEEGATLKTPWAGVPFQVGPSPFLKFTQR--EGEEDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLVEESFQLWELNRR
LEVYL-SRVKALEEQNELLSAELGGLRAQ-SADVSWRARAEDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEAV--AGRCQQQRLARERAAEEAARSRRAVEAEQSSRGWLSS
QAADLERELE----LLRAAHEEERACLNAQAAGAPRGP-APP---RAP-PAPVPEVQ-EL
ALRLGEAWRGAVRG--YQERVEHLETSLGQARERLGRAVQGVREGRLELQQLQAERGGLH
ERRAALEQRLEGRW--QEGLHATEKFQLAVEALEQEKQGLQTQIAQVLEGRQQLAHLKMS
LSLEVASYRTLLEAENTRLQIPGSGPKTSLSFQ---------------------------
--------------------------------------------------DPKPELRFPG
TPEGRRLGPLLPILNLAPVTSPLPDTLKTPMPAFLKSQEFLQACT--PTLASTPIPPTPQ
APRPATDTEIKVQEAPLALLPSQGG-KQQASEPLWTEAKV-AIPASILRRPEEPGGQQRE
ASSGQSPEDQASSAPP--LN----SDPNSLEARDGEPS-------------ASGVSNTAQ
EDSEGQACGLTEEEA----SIEVKAGRSLQQGTWREEGYSDREELQDSV----------K
SLEEELQEPLLSADKQSRETLRGVERERQDGPRAGEEEDSGTP-STPEREDRGQLRSLEE
KSL-EVVGSPAEQTLEPLVPREKEELQTLGSLETETQEPLGSLNESLEAFSFPGKENQE-
LVRSL--EEENG---------------------ESLRALDKDSLEPPPSHEAEDEEVLG-
--KANP------------------------------------------------------
------------------------------------------------------------
----------------------------------------EPLRSLDDAHQEAWRALEQE
KPD---------------------------------------------------------
----------------------------ALKPQGDE-----------HQR----------
----------------------------------------------------LAATDQES
LGLQ--------E--------------------------------------------ETR
ETVRAPEKETQEPQG--------------------------------------------S
LEAEAQKASTPLGA-ESQEQLLSLKADHVEVEKSLELENVESLKSAEEDGLGISKPP---
ELLWPLEEKTQGRPPPMPLEQDQEPLEP-------XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXX---XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXA-TGLAWNT
GGGPPAIPEPNEQKV---PVEGADRARGAEG-----FQDPEGQLEVVRAPDLG--APPGM
PEEVERVLEEEDVVPSRDLASAQ---VALGSDTAVGESGGAA------------------
--EGQEQETVQAQDPDPP---AREEA-MEWPLRDEGLEAEKAPGLGESRRDLKEAETLES
GLAKLPRE---SRDPQRRE---GWAESESERD-SVEEG--FPAETL-------CPDA---
---------PQPRPE------EGAPPELEPSSPR----PTEPWD------DVSGAQP--R
TEGNLEA--GWGLGSGVEALEKLEDRQEQGLDSEGVPG-GLQEEE-----EQSGEESEAD
ELGETLPDSTPLVLFPGSP-----ATSTWDPAGEERPSPQ--GEARQESWGPTASLASEG
----------LGAGPSEAEEE--------GEEEGHSPDSDLSE-EFED-LGTEA------
------SLLPGGPGE--VAEPLRQVPQLL------LEPA-TWDRDEESDGFADEEESGEE
GEDYE----E----EEGRGAGQWGPRSSVGNLQPLSGPQRGDLMKSE--AVGVSV-PWDG
EGPRGVAADAPMPALQ----------PESQDSAEPSSTEAP-------------------
-------------------------------------------VDSDSASLQRE-DAGS-
-GTLETPGGLEGTGHQETGEILGVNGQGPSWGE------HMN----GGLEQSEGGGPGKL
GAPEGGKGNPSEV--EEGDPLEAPWAGIPLRLGQGQFLKFTQR--EEDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SEDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNAQAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQL--------------------------------
------------------------------------------------------------
------------------------------------------------------ELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDAEIRAQDAPVSLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIRGLVEKET----AIEGKMVSSLQQEIWEEQ-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQESPRSLE-EDLDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSLEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHTS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------PLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETLKSPETE
APLWSLEEINQGTMKPL--E-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEERQELPQSADVQRWEDTVG
KDQEL---FQESPAGMAGVENEDEAEL-NLREQDGFAGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPEGQSQPVGAPGLQ--APQGL
PEAIEPLVEDEDVAPRGGQASPE---VTLASEPVTGES---PVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPRK---SRDPWESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPPPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAETLGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEEG
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EG-EECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGRWGPGSSVGSLQALSSSQRGDFLESD--SVGVSV-PWD-
DGLRGAVAGAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------------EESFQMWELNRR
LGGLIWLGSKALEEQNELLSGGSSGVSGRRLGTPPDGARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELESV--AGRCQQLRLARERTAEEAARSRRAVEAEKCARGWLTN
QAAELERELE----ALRAAHEEERASLNAQAA----------------------EVE-EL
AQRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGARESRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATENFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGCRAKASLGFQ---------------------------
--------------------------------------------------DPKLDLRFPG
TPEGRRLGPSLPVLSPTPLPSPLPDTLETPVPAFLKSQEFLQPRA--PTLASTPIPPTPQ
PPIAASDVELRAQDAPVSLLPPQGG-RQQVAEPLWAEAKV-AVPASILPGPEEPGGEQRE
ATSGQAPEDPGPLAPP--LS----PDHPSPEAKDREPS-------------GSRASSLAQ
EEGEGQIDGLVEEAA----AVEVRVVSQVQQAAQ-PAGDLDVEETEDSQ--GPLGEKTQE
ALGEEIPQPLMSPGDQHQEA----PEENQELLGSLGEESSGTL-ASVETENEEPLQPVEE
KDV-EVARPLGGEAPELREPGGREDPRAPQSLEEERQEWGVPLAGGPET--FPGKEDGE-
TVTSP--EEEAA---------------------ESLGAPEEENPELHGSQEGGD------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------PEPQRPLGEESRGSLGSSEEEDLE----------
------------------------------------------------------------
------------------------------------------------------------
-ALRPPQKENQEPPS----------------------PAEEEEQETAPPAAEVDLEPLGS
PGKDQEGVS-PPG--RGRELAKSSEEDNAGAVRAAGAEDLGPLTSA-EGDLEILKSLEMQ
EPQWCLEEVDRGMTTPLGEE-IQERSGS-------LEENQEPLQALEEEEDEGG------
---------------HRDAAEEE-------DEEQSPWCLGEQRQELPRPADQH------T
GSQGL---GQEHP-GKAARASEEEAEL-DPGS----QMAEEEAVQGELQLGA-RGTAWG-
---PPGSPEPREQGV---LAVGASEKEGAEG-----LQEPERQPEQPGAPDLR--APQGV
PEATEPLSEGEAAAPEGDPVSPG---VTLASETAVGEA----------------------
-------AVGAVEDPGHL----AREV-MQPLCGEGGLEVRRVQGLEGPREDPEEADVSEV
EP-----P---KAEPPQPPA--GREASEPETPWGAGEG--SPAETP-------GHTG---
------GEAPECRSLGSEADEDDSQLVLGAPSPR----PPEPRSPTPTLGGAPEPQP--Q
AEGSQEV--SFGLEGRVEATGQVEGEQEEL-GSGEIPEG-LQEEG-----EESREESEAD
ELGETLPDSTPLGLYLGSP-----ASPRWDRAGEQRPSPQ--GYAPEEGWDPAG-LASQS
----------LGAPPPAEEEG--------EGDEECDRDSELSE-EFED-LGTEA------
------SLLPGAPRQ--AAEPLGQVPQL-------LEPA-AWDRDGESDGFAA-------
------------------GAGQWGPGSSAGSL------QRGDFLESE--TVGVSV-PWD-
DGSRAAVADAPVTALE----------TESQDSAKPSGSEE--------------------
--------------------------------------------EFDSVPLERE-DQGP-
-GPVETPRRAEGTSP-GTADTLGINGRGPDLE----ESEHVNGGVVNGLQQPEEVGQGKL
GAPDGDRGSPLAE--EEGAALKTPWAGVPFQLGPSPFLKFMQR--EGEGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SGDTSWRARANDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLAREQTAEEVARNRRAVEAEKCAQAWLSS
QAAELERELE----ALRLAHEEERVGLNA QAACPPRCP-APP---RGP-SAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLESRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTPLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRHLGSLLPVLSPTSLPSPLPATLETPVPAFLKNRELLQART--PALASTPIPPTPQ
APSPAADAEIRAQDAPLSLLQTQGG-RQRAAEPLQAEAKV-AIPASILPGAQEPVGKRQG
AGTGQSPEDHASLAPA--LS----PDHSSLEAKDGETA-------------RSRVFSVCQ
EEGEGQSWGLEEKET----AIEGKVVGSLQQEVCEEE-GMDRKESQDSQ--VPVEKETLT
SLGEEIQDSLKTLESQSHET---LERENQESPRAL--EDLETL-KSLEKENKEPLK----
-EM-EVVRPLEKEGVGLLKPAGKEHTPASQSLPKENPELMKSLEGNLETILSPGKENQE-
LVSSL--QEN-L---------------------ESSTALEKEDQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RP---------------
------------------------------------------------------------
-------------PAV--------EDEEALRPLTKENRELPRSLEDENQEAL--------
-----RPLE-----------------------KENQELPKTPEEEDQSMVRPLETENHES
LRSV--------E---------------------EE----------------------DQ
EALRILEKETQQPRK----------------------SLGEEDQMTLRPPEKGDPEPLQS
LEKDQEIA-RPLEN-ENQELLKSLKEERVEAVKSLEIELLESLKSA-EENLATLTSPGTQ
VPLWSLEEINHGTMIPPEKE-IPEPLGS-------VEVNQETWRLPEEENQEPLRSLGAW
NLENLRSPEEIGKESRSNLAAEESLG----ENRESLRSLEEEGRELPPSADAQSGGDTVA
KDPEL---AQESPPGMAGGENKDEAEQ-NPREQDGFAGKEEVVEQGE--LNA-TGEAWVP
GEGHPGSPEPKEHRG---AAEGASGKGGAEG-----LQDPEGQPQQVGTPGLQ--APQEL
PEAIEPLVEGEDVAPRGDQASPE---VMLGSEPAVGES---AAGAE--------------
--AVPGQEEGRLEGPGHL---TRGEV-MEPPLEEESLEAKRVQGLEGPRKDIGEADALGT
ELSELPGE---SGDPLEPPK--GWEEPEAEAPLGAEEA--FPAETL-------GHNG---
------SDAPPPRPPGSEEAEEAASPVLAPPSPM----Y------TPILEDAPGSQP--Q
AEGSQGA--SWGLEGRSEALGNVESEHEEL-ASGEIPEG-LQEEE-----EQSREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPAGEQSPPHQ--GETGKEGWDPAV-LVSQG
----------LEALPSAEEEGE-------EGEEERGRDSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLGQVPQLL------LEPA-VWDRDGESDGFADEE-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--MGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNA QAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDAEIRAQDAPVSLLQAQGG-RKQAPEPLQAEAKV-AIPANILPGPEEPGGQWQE
AGTGQSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIRGLVEKET----AIEGKMVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQESPRSLE-EDLDTL-KSLEKENKELLK----
-NV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKKNQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSLEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHTS
LRSL--------E---------------------DD----------------------DQ
ETLRTLEKETQQPQR----------------------PLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETLKSPETE
APLWSLEEINQGTMKPL--E-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAW
NPENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRCLEEEGRELPQSADVQRWEDTVG
KDQEL---FQESPAGMAGVENEDEAEL-NLREQDGFAGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLAEDEDVAPRGGQASPE---VTLGSEPATGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPRK---SRDPWESPK-S-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPRPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESDED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGRWGPGSSAGSLQALSSSQRGDFLESD--SVGVSV-PWD-
DSLRSAVAGAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
-----------------------------------------MMESCLGEESVQMWELNRR
LEAYL-SRVKSLEEQNERLRLEIGNLREQ-PGEPSWRSQAEEELGALRALL---DQRWSE
KHAAEVA---RDNLLEEVEGV--ASRCQQQLLARERAKEQVAESRRVLEAEKWAGVCLGN
QAAELEKELE----ALVAAHEQERAGMSAQVARSALGLETFR---RAPDNAPAPDVQ-DL
ARTFGDAWRGAVEG--YQARVACMEASLGQARERLGQAMQGTREGQREAQRLDVERAALQ
GRREMLEQRLEGQW--QEQQEAGEKFQLAVEALEQEKQDLHNQIAQVLEDRQQLTHLKMS
LSLEVATYRTLLEAESSRLNTSNIDSKATIIFP---------------------------
--------------------------------------------------DPKMELCIPV
TPEIRHPGPWPPVLSPTSLP--MVDTPRTPMPAFLKSQGFLPTQT--PTLASTPIPAISQ
AHHPGTGREVQGQ-----------------------------------------------
---------------DKKIVLATDSSIDPLAAKDGEEKDGELNDISSP-QPPAPEPSKYQ
EKVGKEIQGVAEEDE----T-KETIAENLEEKTWQKGGALDKEEIQ--------------
-------ERPGTSDEKVQETFGILSGKIRETLNLPGEEVQKTQ-KLPSEEFQEMQI-LPG
EEIQETQRLPDEKIQET-HIFPGEEIQKSKE---------LPTEEFQEIQILPGKEVQE-
TQKLP--NEEFQE----------IQILPDELI--------QETQ---KLPDEEIQDTHIF
PGEEIQKSKKLPTEEFQDIQILLGEEIQETQKLPSEEGQETQILPDEEIQE---------
------------------------TQILP-------------------------------
---------------------DEEIQETQSL-------------------------PSEK
IQETLILPGEEIQGIQNLQTDENQEILSFPGEDKQEIMMPLEKETQETLRSL-EDNEETL
NSPKEGNLE---------------------------------------------------
-------------------------------IGENQETIGFPGEKKQETLSPLEEGVLE-
------------------------------------------------------------
------KKENQETLGSPKENNQEIVSSPEEGD-----LERENNQEIQGPPEENNEEIPKP
QKGDLERE---------EEKSGSLK-----------------------------------
------------------EE-IQGILCFSEEGNQERGEMQEIPTLPEKEIQESLTSLDEG
NLETEENQE---------IPEEGKGALERKENQEILQSLEVESLDL------QKPEDVAG
IGQDCSIEGDEKAPWETGKDHEETAKR-KPEEQSSLEGNWEVVEEAGLRYGG-SGESQHA
GEEELGSQESEQQRF---PTKETIKEGITTS-----PQVEFR---EVESTEFE--ALNCV
PKMSEQMFEEDGSSRESDGEAPEDNGSITGLEPLEGEE----------------------
---VRNQEQLKKEVSESE---NWEGGLSEPHHREVILEPSLEQSDRETEKDVQETNELNQ
QYSKLLMENETPHPHLETPE--VLEKPEQKNSLGMGEDSRHPSDLLP-AETTIANNVDG-
------GTTTQSS-------------FMGQGGPQE------IKQEVDISEDPLESHF--R
AEGNKELWESWETEGKTEVSEELERLM---------PKT-AQQS------FRGVEESEGD
DLSETL-DSTSLGLYSREP-----DSPSWGMIAKEHPSPQ--EEHNDEPWDPPP-RHTEV
----------SRAQPDEGED------------EDGAPDSDVSE-EFED-LAVDA------
------SLLPGGPGR--LMETVGPGSELV------LDPP-TWDRDRESDGFADEEER---
---------------------------------------E--PEEDR--ERNAHA-PSD-
AGRREGAENFPPAILEVEKETKPLDRPKSLDSDIQSDSEEEHSHVTEDPEDSGP------
------NE---------------------EELETPLPSNQSLFGVSDPTLLDKE-DQASD
SDLIEIPCRVDDSAR---KAGTSLNGGGPTMDQ----PDDIRGDILNGLGKLQEADQGKL
WDLEREGGEGKAP--GEELSSQTLWSGGPLILGQSPFLKFTQT-KEEDRDSWSSGDE---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLQLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNA QAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DAKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PALASTPIPPTPQ
APSLATDAEIRAQDAPLSLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGLSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIWGLVEKET----AIEGKMVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHEA---LERENQESPRSLE-EDLDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPVGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTV----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHKS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------SLGKEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLEKELLQSLKSAGQENLETLKSPDTE
APLWSLEEINQGTMKPL--E-VQEPLES-------VEVNQETLGLLEEENQEPLRSLGAR
NLEDLRSPEEVDRESQRNLEEEENLGKG--ENQESLRSLEEEGRELPQFADVQRWEDTVG
KDQEL---SQESPAGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPEGQSQQVGAPGLQ--ASQRL
PEAIEPLVEDEDVAPRGDQASPE---VTVGSEPATGES---AVGAE--------------
--PGPRQEVGGLKDSSHL---TGEEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPGK---SRDPWESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPRPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQRRAEALGKVESEQEEL-SSGEIPKD-LQEEG-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVLGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGQWGPGSSVGSPQALSSSQRGDFLESD--SVGVSV-PWD-
DSLRGAVAGGPMNTLE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPTLEE---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGASVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNA QAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDAEIRAQDAPVTLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIRGLVEKET----AIEGKMVSSLQQEIWEEQ-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQESPRSLE-EDLDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSLEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHTS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------PLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETLKSPETE
APLWSLEEINQGTMKPL--E-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEERQELPQSADVQRWEDTVG
KDQEL---FQESPAGMAGVENEDEAEL-NLREQDGFAGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLVEDEDVAPRGGQASPE---VTLASEPVTGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPRK---SRDPWESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPPPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGRWGPGSSVGSLQALSSSQRGDFLESD--SVGVSV-PWD-
DGLRGAVAGAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

--------------------------------------------MNSLAPTPDSQSLRLL
LAPPRHCPHP-SPFPFRPKSFESCWPVLVLCVPPPSVGQTSRMEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELKGLRAQ-SGVASWRARADDELAALRALV---DQRWLE
KHAAEVA---RDNLAEEVEGV--AGRCQQLRLARERTSEEVARSRRVVEAEKCAQTWLST
QAAELERELE----ALRAAHEEELAGLNAQ AACAPRGP-APP---RGP-PTPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGHAMQGAREGRLELQQLQAERSGLQ
ERRAALEQRLEGRW--QERLRATEQFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSGSKASLSIL---------------------------
--------------------------------------------------DPKLELHFPG
TPEGRRLGPLLSVLSPTPLSSPLPDTLDTPMPAFLKSQEFLQART--PTSASTPIPPTPQ
APCPAPDAEIRDQDAPLSLLQPRVG-RQQAPEAVQAEAKV-VIPASVLPGPEEPGGKQQE
AGPGQAPEDQAPLAPA--LS----PDRHSLEVKDGEPS-------------ESRESSRFQ
EEGEGQIWGLAEKET----AVEVKAVSSLQREAQQEEGDLDVKEIQDAQ--ELLEKESLK
SPEEEIQEPLVSLEKQSHETMRSLEQENPESLRSLEEENLETL-KPLEEGNQELLASLEE
KEM-EVVRSLEKETLELLKPVEKEDPQTLQSLEKENQETLRSFEGNEETFLCPRKENQE-
LVTSL--EEENLL---------------VRSLEESLRAQEKESQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSQDIENQEALRPLAKE
GQE----------------------PLKSLEE-DQE----------------------TV
RPLEKENHESLWAPED--------ECHETLRPLEKENQKSLRSLEDQE------------
------------------------------------------------TTGSPEKENQEP
LRSP--------E---------------------DE----------------------NQ
DTLRPLEKEAQQPLK----------------------SLGEEDQVTLRPLEEVKPEPLES
LEKAQEID-RPLEK-DNQALLRSLNEESIEAVRCSETETLEALKSI--------------
------GEENQDIAKRLEEE-SQEPLGS-------GEGNQETLSPLEKEHRASLSSLGER
NLENWRSPEEEGKESQRYLEAEENVEKR--ETPEPPRSLEEEEQATPPSAHQQKWDDVGG
VQREL---DQEAPPGKAGVDSEDKADL-DQREQDGIDGKGEAGEQA---GEA-TGEAWST
GGGQPGSLEPEEQSV---PAEGASGEGGTQG-----FQDPEERPGQEGAPGFR--APQGI
SEVIEPVLED-DVPPADGQASPE---VALGLEAAVGESE--SMGAE--------------
--QGPEQEAGSLEESGGL---AREDV-TESPLGEEGLEAKRVQGLEGPRKELAEAVALEP
ELAALPSE---RRDLLEAPG--GWEESKPEAPGEAEEA--FPTETL-------HHSG---
------SDAPQPRPLGSERAEEEAESVLGPPSPR----PAESSSPTPNPEDALGPQC--L
AEGTQET--GWGLEGRAEV---PEGEQEDL-GSGEIPEG-LQEEE----EEESREESEAD
ELGETLPDSTPLGFYLRSP-----ASPKWDLAGEQRPSPQ--GETRKEGWGPAA-LAPEG
----------LGAHPSEEE---------GDEEEERGRDSELSE-EFED-LGTEA------
------SLLPGVPGQ--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEESGEEG
EEE------DEEEEGRKPGAGRCGPGPSAGSLPALSDPQRGSLLGSE--AVDVSV-PWD-
DGSRGVAFDAPMTALE----------TGSQDSAEALGSEE--------------------
--------------------------------------------ESAAAPLERQ-DHIP-
-GPLETLGGVEDMAL-EVGDTFGVNGQGPSLKE---ELEHVNGGVVNGLEQPVGVGQGKA
GALEGVQGTPLEG--EEGGALKTPWAGAPLHLGQSQFLPFTQR--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MESCLGEESVQMWELNRR
LEAYL-SRVKSLEEQNERLRLEIGSLREL-PGEPSWRSRAEEELNALRALL---EQRWSE
KHAAEVA---RDNLLEEVEGV--ATRCQQQRLARERVKEQLVESRRVLEAEQWAGVCLGN
QAAELEKELE----ALVAAHEQERAGMSAQVARSAMSLETFR---RAPDNAPAPDVQ-DL
ARTFGEAWRGAVEG--YQARVACMEASLGQARERLGQVMQGSREEEREAQRLDVERAALQ
GRREMLEQRLEGQW--QEQQEAGEKFQLAVEALEQEKQDLHNQIAQVLEDRQQLMHLKMS
LSLEVATYRTLLEAESSRLHTSKINSKASVIFP---------------------------
--------------------------------------------------DPKVELCIPV
TPEIRRPGPWPPALSPTTLP--MVDTPRTPMPTFLKSQEFLPTQT--PTLASTPIPPISQ
AYHSGTRREVQAQVAPSYLLQGPSF-DGPKPKLPWAKAKV-GIGVDSSPGSEEPGVEKQQ
VPSFPCPAT--------------DSGIDSKETKDYEKENEKLSDFNSP-QAPSTEPNKYQ
-KEEKEIQGMAEEEE----A-KETIVESLEGETWLKGRALDGKEIQENL-----------
SLPDKIQETPEISEEKFPETLRILSGELTETLKLPGEEIQEAQ-KLPSEKFQEVQI-LPG
EEIQEAQKLPVKEIQEA-QKLPGEEIQEAQK---------LPGEEIQEVQKLPSEEFQE-
VQKLS--SEEIQK-------------LPSEEIQEVQKLSSEEIQ---KLPSEEIQEVQKL
PSDDIGETQKLPSEEFQEIQILPGEEIQGIQKLPNEKFQEAQKLLGEEFQK---------
------------------------VQILP-------------------------------
---------------------GEEIQEAQEL-----------------------------
-------LSEKFQETQILPDEEF-------------------QKT---WRSLGEENREIL
SFLKEGNLE---------------------------------------------------
-------------------------------REENQDSLSSPEENKQETISSVE-GVLQ-
------------------------------------------------------------
------KKENQETLEFPEDN-QEMVSFPE-EN-----LEREDNQETTGPPEEENQEIPKP
-----------------------LK-----------------------------------
------------------EE-IQEILYFS-EGNQKREELQEMLALPEKEMQETLKSLDDG
NLEMEEDQE---------VPEEGKGYLERKENQETLQCLEVQSLDL-------ASMDVAT
MDQEHSSREDEKAACELGKDHKEIAEL-KPGEQSGVEENWEVVEGTGSKYGD-PAESWQA
EEEELGSQESEEQKL---PSKETIEEGMTKG-----PQMEFR---EVGSLELG--AV---
---TEYILKEDGAFRESDGVTLGDNGSITGLEPSERKE----------------------
---VRNQEWLEKEVLESE---KWEEGPSEPHFKEVILTSA-EQFEKKTEKDVQETGMGED
--------PGSPSDTLSAET--TIDNTADGKG----TTTQSGLMGHASSQEEIKEEIRAS
-----E--NPQSS------------Q-VEG-DPEQM-----PQSFSSLPKDSLESPF--R
AESNQELWESWETEERPRSI-----------------------F------QEEVEESEED
DLSETLPDSTPLGLYSRNP-----DSPSWGIIGKKQPSLQ--EEPHNAVWDPSP-SHAKA
----------SKVQPCEGEED--------EE---GA---ADCE-EFED-LAADA------
------SFSPRGSEG--LVETEGHGSEMV------LNPP-TWDRDGESDGFADEEENGEE
EEED------DDSDGRGEEIRHWKLGPSLGSPVSYHQEEE--PFENM--DRNADA-PLD-
TEEREGIENPSPEVLEVEKEIKLSGRPKSLNSDIQSDSEGV-------------------
---------------------------------------------SDLTPLDKE-GQVTD
GDLIEIPCKVDDGVR---KSGASLNGGGLSLNQ----PDDIRAEILNGLGKLEEAGQGKL
WDLEREGGEGKAA--GEELSSQTLWSGGPLILEQRPFLKFTQN-KEEDRDSWSSGDE---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SADTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLVRERTTEEVARNRRAVEAEKCARAWLSS
QAAELERELE----ALRVAHEEERVGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEDRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSPAADAEIRAQDAPLSLLQTQGG-RKQAPEPLRAEARV-AIPASVLPGPEEPGGQRQE
ASTGQSPEDHASLAPP--LS----PDHSSLEAKDGESG-------------GSRVFSICQ
GEGEGQIWGLVEKET----AIEGKVVSSLQQEIWEEE-DVNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQECPRSLE-EDLETL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVGDEEALRPLTKE
NQE----------------------PLRSLEDENKE----------------------AF
RSLEKENQEPLKTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHKS
LRSL--------E---------------------QQ----------------------DQ
ETLRTLEKETQQRRR----------------------SLGEEDQMTLRPPEKVDPEPLKS
L--DQEIA-RPLEN-ENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQ
APLWTPEEINQGTMKPLEKE-IQEPLES-------VEVNQETLRLLEEENQESLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--EYQESLRSLEEEGQELPQSADVQRWEDTVE
KDQEL---AQESPPGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--LNA-TEEVWIP
GEGHPESPEPKEQRG---LVEGASVKGGAEG-----LQDPEGQSQQVVAPGLQ--APQGL
PEAIEPLVED-DVAPGGDQASPE---VMLGSEPAMGES---AAGAE--------------
--PGPGQGVGGLEDPGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGT
EFSELPGK---SRDPWEPPK--GREESEAEAPRGAEEA--FPAETL-------GHTG---
------SDAPSPWPLGSEEAEEDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPEG-LQEEG-----EESREESEED
ELGETLPDSTPLGFYLRSP-----TSPRWDPTGEQRPPPQ--GETGKEGWDPAV-LASEG
----------LEAPPSEKEEGE-------EGEEECGCDSDLSE-EFED-LGTEA------
------PFLPGVPGE--VAEPLGQVPQLL------LDPA-AWDRDGESDGFADEEESGEE
GE-------EDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESD--SVSVSV-PWD-
DSLRGAVAGAPKTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEIPSGMEDAGP-GA-DIIGVNGQGPNLEG---KSQHVNGGVMNGLEQSEEVGQGMP
LVSEGDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNA QAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATEAEIRAQDAPVTLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIRGLVEKET----AIEGKMVSSLQQEIWEEQ-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQESPRSLE-EDLDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSLEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNSL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHTS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------PLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETLKSPETE
APLWSLEEINQGTMKPL--E-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEERQELPQSADVQRWEDTVG
KDQEL---FQESPAGMAGVENEDEAEL-NLREQDGFAGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLVEDEDVAPRGGQASPE---VTLASEPVTGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPRK---SRDPWESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPPPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGRWGPGSSVGSLQALSSSQRGDFLESD--SVGVSV-PWD-
DGLRGAVAGAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-AGDASWRARADDELAALRALV---DQRWRE
KHAAEMA---RDNLAEEVEGV--ASRCQQLRLVRERTAEEVARSRRAVEAEKCAQAWLST
QAAELERELE----ALRAAHEEERAGLNAQ AACAPRGP-APP---RGP-PAPAPEVE-EL
AQRLGEAWRGAV RG--YQERVAHMETSLGQARERLGHAMQGAREGRLELQQLQAERSGLQ
ERRAALEQRLEGRW--QERLRTTEQFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSGSKTSLSFL---------------------------
--------------------------------------------------DPKLELHFPG
TPEGRRPGPLLSVLSPTPLSSPLPGTLETPVPTFLKSQEFLQART--PTSASTPIPPTPQ
APCPAVDAEIRAQDAPVSLPQPRVG-RQQVPEVMWAEAKV-AVPASILPGPEEPGGQQQE
PSPSLSPEDRASLAPA--LS----PDHSSLETKGGEAS-------------GSRESSRSQ
EEDEGQLWGLAEKET----VVEVKAVSSLEQETWQEEAGLDRKEIQDAQ--GPLEKEAVN
SLEEEIQKPSIPLGKQSHETVRALEKESLESLRSLEEENLETL-KILEKENQELLKSL--
----EVVRSLEKETLELLKPIGKEDPQTLPSLEKENQEIMRSLEVNGETFLYPGKENQE-
LVRSL--EEENI---------------------ESLRTLEKESQEPLRCQEVENQETLRL
LAKENQEPLGSLEEEDQETSRPLGKENHESLRAPEDENHEALRPLERENPESLSC-----
-----------------LEE-DQE------------------------------------
------------------------------LLRSLEKENQEPLRALEE-DQETMTLS---
------------------------------------------------------------
-PL---------------------------------------------------------
--------EEVKP-----------------------ETLKSL-GKDQEIVRPLEKENQE-
--------------------------------------------------LLRSLNEESI
EAVRSLETEAP----------------------E--------------------------
------LL-KPTED-ENLEILKPLE-----------------------------------
----------------KEKE-SQEPLGS-------VEGNHETLRPPGKENQESLGSLAEW
NTENLQSLEEADKGSLRHLEEEEIVEKE--ESQASLRPLEEQGQELPLSAQQQTWGDAMQ
RDQEL---DQDQPLGRAGVDSGDGAEL-ELEERDSFPAEGEVVEQGQLQLTA-TGEAWGL
GEGQPGSPEPKEQRL---PAEGTGGAGGAGG-----LQDPEEQPEQVGALGLP--AAQGM
SEVMEPELEDEGVAPGGGQASPE---VTLELERAMGRSAG--------------------
VERGLQQEAVRLEDPGSL---AREEA-TEPPLGEGGVEAKKVQGLEGPRKELEEAGTLES
EVSTLPGK---SRDPLETPR--DWEESESGAPGKIEEP--VSAETL-------CHEG---
------SDTPQPRPLGSEGAEEDAKSLLGPPSLR----PTD-----LIPEDAPGPQP--L
AEGNQEA--SWGLEGRAEVLGKAEGEQEDL-GSGGIPEG-LQEEG-----EESREESEAD
ELGETLPDSTPLGLYLRSP-----ASPKWDLPGEQRPSPQ--GEPGKEGWGPAV-PASKG
----------LGAQPSEEEEEE------GAE-EERGRDSELSE-EFED-LGTEA------
------SLLPGVSGEGEGEEPLSQVPQLL------LEPA-AWDPDGESDGFADE-ESGEE
GE---------EEEGREPGPGRWGPAPSVGSPPTPSGPQGGPLLGSE--TVGVSVPPWD-
NVPGGAAPDPPMTALE----------TESQNSTEASGSEE--------------------
--------------------------------------------ESDAAPLEPE-DQAP-
-GPLGTLSGVEDT--------LDGGGPGPSLKE---ELERVNGGVVNGLEQSEGGGQGKP
GAAGGDRGSPSE---EEGASLKAPWAGAPLHLGQGQFLKFSQR--GGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MDGCVGEESFQLWELNRR
LEAYL-TRVKALEEQNAQLSAELGGLRAQ-SRDASWRAGADGELAALRALV---DQRWRE
KHAAEVQ---RDSLADELEGV--AGRYQQLRTARERSVEEAARSRRAVEAEQRAQDWLSA
QAAELERELE----ALRAAHEEERAGLHAQV ACAPRRP-AFP---RGP-PAPAPEVE-EL
AQRLGEAWRGAV RG--YQERVAHLETSLGQARERLGRAMQGAREGRLELQQLRAERGGLQ
QHRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGSSKAFLSFQ---------------------------
--------------------------------------------------DPKLELHFPG
TPEGQHLRP---VLSPTSLPSPLPNTLQTPVPMFLKSQGLLQAHT--PTLASTPIPPTPQ
APCPAANAEVRAQDGPCSLLPQQGG-RQQTPEPLWAEAQAAAVSTSILPGPEEPGGKH--
--PGQFLEDQAPLAPP--LS----PDQPSLEAKDGDPS-------------GPGAPSTLQ
EEGKGQMWGLVEKET----AIEVQVVSNLQQQTWQGE-DLDVKKVQDSQ--DPV-EETQK
PLGEEIQQPLMPLENQSHET---REKEDRESLKSLEEENRETL-KSLEEENQEGLKSLED
NDI-EAEKPLEKEVIELPKSVGKEDSQILQSLERENQELMTSLEGKLETVLFPGKGNKE-
LVRSV--EEENLE--------------------ESLRTLKKETQKPLKSQEAEDQEIWKS
LPTENWESLKSFEDETQETLKDNQ-----EPLTSLE------------------------
--------------------------------------ENEE------------------
--------------------------EDETFVKTLEKKDQESLRSLEAVDQRGVRVLEQQ
NQE----------------------TLRSLEEEEEKTM----------------------
GPLERETQEPLRSLEE--------EEAQTVRTPEKENQESLGSLG--DQETM--------
-----RPLE-----------------------EENLEPLGSLEEKDQKTKRLLEKEDQEQ
LRSL--------E----------------------E----------------------NQ
ETLKILEKETQQSLR----------------------ALRGEGQMTLRLSEKVNLEPLES
LRNEQDIV-GSLEK-EHQELLKSLKGDSTEAVRPSDTQNLEPLISA-EEDLEMLKSLEVQ
ESLWPLEERNRETVKPLEKE-IQETLES-------VEENQGVPSLQEKENQETLKSSGEW
NLENLRSPEEAGKEDHTDLEKGGSLLKE--ENQELLRSPEEDAQELPLSENQQRCEDVAM
GDQGL---GQEAPPRREEVGDKGEAEP-GVREQGGN---------------S-AAEAW--
-----------EQRA---PAEGASGQGGTED-----PQDLEGPAEQVGAPGLR--ASQGM
TDVMEPQQEDEDEGLGGGQASLD---VAWGSETAKAMM----------------------
---ELEQEVGGLEDREDLVRAALEEA-VQPPPGEDNLEAESAEDLEGSGQH-----QVEA
PLPNLPGS---SRDLGEPPK--GLEESEPEAPVGTEEV--SH------------------
------TDAPQPKPKGSGDCP-GTQPVLGPTEP---------HAPTPIPEDSSGPQY--Q
NEGDQEA--GWGLPRRAEDLGKEEEEEE-----------GEEEEKEE--EEESRAESEAD
ELGETLPDSTPLGLYLRSP-----SSPGWDVVGEQRPSPQ--GEARKEGWETGV-Q----
--------------------------------GDRGQDSDLSD-EFED-LETEA------
------SFLPGAPRK--VAEPLGQMAQL-------LEPA-VWDRDGESDGFADEESGEEA
----E----DEEEKGIEPGAPRWGPGSSVGSLQALSSSQRGDLLAPD--SLSINV-PWD-
DGLQGAMAGDPVTAPE----------AESQDSAEPSGSE---------------------
--------------------------------------------ESDSAAWE-K-NQVP-
-GPLETPSGVEDTGL---GDAHSVNG-GPNLEE---ESEHTNGRVVNGLQQSKGGGHGAP
EPPDGDREISQI---EEGVALKTPWAGAPLHLGPSQFLKFTPR--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQMWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADDELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELESV--AGRCQQVRLARERTIEEAACSRRALEAEKNARGWLST
QAAELERELE----ALRASHEEERAHLNAQAACTPRRPPAPA---HAS-PIRAPEVE-EL
ARRLGEVWRGAVRD--YQERVAHMESSLGQARERLGQAVRGARESRLEVQQLQADRDSLQ
ERREALEQRLEGRW--QDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRSSQASLGFP---------------------------
--------------------------------------------------DPKLKLHFLG
IPEDQHLGSVLPVLSPTSFSSPLPNTLETPVTAFLKTQEFLKART--PTLASTPIPPMSE
APYPK-NAEVRAQDVPHSLL--QGG-RQQAPEPLWAEATV-PSSTGVLPELEEPGGEQ--
--PDHFPDDPTSLAPP---L---NPHHSILEAKDRESS-------------ESRVSSIF-
QEEEGQIWELVKKEA----ATEVKVENSLAQEIQES--GLDTEEIQDSQ--GPLQMETLE
ALGD---EPLMSLKTQNHET---PGKENCNS--SIEE-NSGTV-KSPEKEKQTPLKSLEE
KNV-EAEKTLENGVLELSKPLGEEEP------RMEDQEL-MSPEHTLETVSFLGKENQE-
VVRS-SEEQNLESLITFKEESQYPLGGPEAEDQMLERLVEKEDQRFPRSPEE-DQQAFRP
LEKENQEPLRFEEAEDQVLERLIEKERQESLKSPEEEDQQAFRLLEKENQEPLRFEDAED
QVLERLIEKERQESLK--------------------------------------------
--------------------------------------------SPEEEDQQAFRLLEKE
NQEPLRFEEAEDQVLERLVEKESQESLKSPEEEDQRTGKPLEKENQESLRSLDE-NQETI
VLLESKNQRPLRSLEV------EEEEQRIVKPLEKVSQVSLESLEKENVQSPRYLEEDDH
--MIKSLLEDKTHEILGSLEDRNGENFI-PPENETQGSLRPPEEEDQRIVNHLEKESQEF
LRSPEAE---EEEEQVMVRSLEGENHDPLSSVVKEEQMA-ESKLENESQDSRKSLEDESQ
ETFGSLEKENLESLRSLAGQDQEEQK-LEQETQQPLRAVED-EQMTVNPPEKVDPELPKP
LRNDQEVV-RSLDK-ENQESLVSLNEGGMETVKSSETENIESLETV-GECLGRRKSVDTQ
EPLWSTE-VTSETIEPLEDE-TQEPLGC-------VDENQEVLTPLERESQE-LRSLGKW
NPETVESPGGVED-SQQCLEVEEGPERE--QHQESLRSLGEVEWELPGSGSQQRWEDVV-
EDGE----GQEASLGATGVETEDKAEL-HLR---GQGGEEKAVEEGELLQDA-VGEAWSL
G-----SSEPKEQRV---PAE---------P-----LDDLEGQPEQTGTLEVP--VAQGM
PEATE---QDEDRAQAGEQDSVE---VTLGLEA-ARAG----------------------
--LELEQEVVGLEDPRHF---AREEA-IHPSLGEESVKAKIDQGLEEPGKEPKEAGALDS
GIPELPKT---SSETLECK---GWEE--SGEGWGEEEA--S-LETS-------DHEG---
------SHAPQPRPPKTEED-EGLQAALTVPGPK----LLEPCSPIPILTDAHELQP--Q
AEGIQEA--GWQPEAGTEALGRVEDEP-EF-GRGEIPEG-LQDWE------EGREDSEAD
ELGETLPDSTPLGLYLKSP-----ASPKWEQAGEQRLFPQ--GEARKEGWSPAA-LAAQG
----------LSDPPEE---------------EQQGHDSDLSSEEFED-LGTEA------
------SLLPGVPKE--VSDHLGQEPPV-------LQPA-CWDQGGESDGFADEEESGEE
GEEED----ADEEEGAESGTQWWGPGPSGGGVKVQDVTQRGDL-EHE--SVGDSG-LWD-
DGLSGAAANVLVTALE----------TVSQDSAEPSGSE---------------------
--------------------------------------------GSESASLEGEEGQAI-
-DHLDAPQEVTSVVP-GAGDTFDISGQGPNLE-----SEQVNGRMENGLEQAEGQVVL--
-HGDEDQGIPLQE--Q--GTLKAPLVGSPVHLGPSQPLKFTLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MDGCVGEESFQLWELNRR
LEAYL-ARVKALEEQNAQLSAELGGLRSQ-SGDTSWRAGADGKLAALRALV---DQRWRE
KHAAEVQ---RDSLADELEGV--AGRCQQLRMARERSVEEAARSRRAVEAEQRARDWLSA
QAADLERELE----ALRAAHEEERASLHAQV ACTPRRP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAV RG--YQERVAHLESSLGQARERLGRAMQGAREGRLELQQLRAERGGLQ
ERRAALEQRLEDRW--QERLRATEKFQLAVEALEQEKQGLQNQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGSPKTFLSFQ---------------------------
--------------------------------------------------DPKLELHFPV
IPEGQHLGP---VLSPTSFRSPLPNMLQIPVPAFLKSQEFLQART--PTLASTPIPPTPQ
AACPAAIAEARAQDDPCSLLPPQSG-RQQAPEPLWAEAQE-ATTAGILPGPEEPGSKQQE
ASPGQSPEDQASLTQL--LS----PDQPSVEAKDRELR-------------WSRTSSVSQ
EEGKEQMRGLVEKET----TIEVQVVSSLQQQTWQEGEDLDMKEIQDSQ--GPLEKETLK
VLGEEIQQPLMPLENQSHEA---QEKEDQEFLKSLEDENLETL-S-LEKENQE-VRSFEE
KDM-DAERPLEKEITELPESTGKENSQRLQSLEKEHQD-------SLETVLFPGKGNQE-
LVRSL--KEENLE--------------------EALRMCEKETQKPLSSQEVEDQEMWKS
LPDENQESLKYLEDETSKD--------NQEPLTFLEENGKTVKPLEKEKQELL-------
-------------------------------------KSLEE------------------
--------------------------EDKKFVRTLEKEDQESLRSLETADQGNVGALEKE
NQE----------------------SLRSLEEEEEKAMRPSEKESLEQLKYVEE-DENTV
RPLEKEKQEPLGSL----------EDQKTMRPLEKENEERLWSLEE-GQKNV--------
-----RPLE-----------------------KEKQEPWKSLEEQDQKIMRPLEKGDQEL
LNSL--------E----------------------E----------------------DQ
ETLQTLEKETQQSLR----------------------APGEEGQMTMRLLEKMNPEPLKS
LGNEQETV-RSLEK-EDQELFKSLKGESTEAVRSSDIQNLESLKSA-EEDLEMLKSPEAE
ESLQSLEKRNRETVKPLEKE-MQETLGS-------VEENQEMLSPQEKEKQERLRPVGEW
NLQNLRSPEEAGKEVHKDLETEGSLLNG--ENQELLRSLKD-TQELPLSENQQIWEDIAM
EDQDL---AQEAPSSREEVGDEGEAEL-GLREQDGN---------------S-AAEAWSI
G-----TPEPKEQRD---SAEGANRYGNAEG-----PQDLQGPPEEVGAPGLG--ASQEM
AEVAEPRQEDEDEGPESGQGSLG---VTWESETVKSLS---AAGAE--------------
--LGLEQGVGELEDQKDLAHSALQET-GQSPPVEDNLEAESAQGLEGSGQD-----HMES
ALSDPPSR---SMNLGEPPK--GWEELEPEASVGTEEV--SP------------------
------SDAPQPRPLGSEDAQ-DAQPVLGPTEPH---------APTLIVEESSGTQL--Q
NEAGQEA--GWGLKGRTEVLGKVEGEQEEL-GPEEISED-LQEEE-----EESRAESEAD
ELGETLPDSTPLSLYLRSP-----SSPGWDMAGEERPSPQ--GEARKEGCDPAV-PG---
-------------PPSEEE----------DGEDDRGQDSDLSD-EFED-LETEA------
------S-LPGRPKN--VVEPLGQVAQL-------LEPA-VWDRDGESDGFADEESGEEA
----E----EEGEEGQEPGALQWGPGSSVGSLQTLSSSQREALLAPE--PLGINV-PWN-
DSLQGAMVDVPVTAPE----------IESQDSAEPSGSE---------------------
--------------------------------------------ESDSAPWE-E-DQVP-
-GPLETV---EDTGP-GD--NHSING-DPNLEE---KSENTSGRAMNGLEQSRGEGHGTP
EPPNGDQGASSQV--EEGVALKTPWAGAPVHLGPSQFLKFNLR--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SADTSWRAHADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTTEEVARNRRAVEAEKCARAWLSS
QVAELERELE----ALRVAHEEERVGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLL
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPR
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSPAVDAEIRAQDAPLSLLQTQGG-RKQAPEPLRAEARV-AIPASVLPGPEEPGGQRQE
ASTGQSPEDHASLAPP--LS----PDHSSLEAKDGESG-------------GSRVFSICR
GEGEGQIWGLVEKET----AIEGKVVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQECPRSLE-EDLETL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQELMKSLEGNLETFLFPGTENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVGDEEALRPLTKE
NQE----------------------PLRSLEDENKE----------------------AF
RSLEKENQEPLKTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHKS
LRSL--------E---------------------EQ----------------------DQ
ETLRTLEKETQQRRR----------------------SLGEQDQMTLRPPEKVDLEPLKS
L--DQEIA-RPLEN-ENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQ
APLWTPEEINQGAMNPLEKE-IQEPLES-------VEVNQETFRLLEEENQESLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--EYQESLRSLEEEGQELPQSADVQRWEDTVE
KDQEL---AQESPPGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--LNA-TEEVWIP
GEGHPESPEPKEQRG---LVEGASVKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLVED-DVAPGGDQASPE---VMLGSEPAMGES---AAGAE--------------
--PGPGQGVGGLGDPGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGT
EFSELPGK---SRDPWEPPR-EGREESEAEAPRGAEEA--FPAETL-------GHTG---
------SDAPSPWPLGSEEAEEDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPEG-PQEEG-----EESREESEED
ELGETLPDSTPLGFYLRSP-----TSPRWDPTGEQRPPPQ--GETGKEGWDPAV-LASEG
----------LEAPPSEKEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------PFLPGVPGE--VAEPLGQVPQLL------LDPA-AWDRDGESDGFADEEESGEE
GE-------EDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESD--SVSVSV-PWD-
DSLRGAVAGAPKTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEIPSGMEDAGP-GA-DIIGVNGQGPNLEG---KSQHVNGGVMNGLEQSEEVGQGMP
LVSEGDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MDGCVGEESFQLWELNRR
LEAYL-ARVKALEEQNAQLSAELGGLRAQ-SGDNSWRAGADGELAALRALV---DQRWRE
KHAAEVQ---RDSLADELEGV--AGRCQQLRTARERSVEEAARSRRAVEAEQRAQDWLSA
QAAELERELE----ALRAAHEEERASLHAQ AACAPRRP-APP---RGP-PTPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHLETSLGQARERLGRAMQGAREGRLELQQLRSERGGLQ
ERRVALEQRLEDRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSSFKASLSFQ---------------------------
--------------------------------------------------DPKPELYFPG
TPEGQRLGPV--VLSPTSLPSPLPNTLQTPVPAFLKSQEFLQART--PTLASTPIPPTPQ
APCPAANAEARAQDGPCSLLPQQGG-RQQAPEPLWDEAQA-AITASILPGPEEPGGKQQE
ASPGQSPEDQASLAPP--LS----PDEPSLEAKDREPS-------------GSGASSVFQ
EEGKGQSQGLVEKEV----AVEVQIVSSLQQQTWQEGGDLDVKEAEDSQ--GPLEKETLK
AVGET-PKPLMLLENQSHEA---REREDRESLKSLEEENLETL-KSLEKENQEGLRSLEE
KDM-EAERLLEKEVTELPKSVGGEDSQTFQSLETENQGLMLSREGNLETVVLPEKENQE-
LVRSL--EEENLE--------------------ESLSTLKKETQKPLSSQEAEDQEIQKF
LPEENQESLKSLEDESQETFKDN----QEP-LTSVEENEKTVRPLEKEKQELL-------
-------------------------------------KSLEE------------------
--------------------------EEEEFVKTLEKDDQESVRSLEVADQGNVRPLEKE
NQE----------------------SLRSLEEEEEK----------------------TV
RPLEKENQEPLGSL----------EDQETLRPLDKEDQGPLWTQEEEDQKNV--------
-----RPPE-----------------------KENQEPLESLEEEDQKTMSPLEKENQEL
LRSL--------E----------------------E----------------------DQ
ETLKTLEKETQQSLR----------------------ALGGEGQVTLGLLEKVNPEPLES
LGNEQEVV-GSSEK-EHQELFRSLEGERTEAVRSSDTQNLEPLTSA-EEDLEMPTSLEAQ
ESLWSLEERNRETAKPLEKE-IQETQGS-------VEENQETPSPQEKENQETLRPLGEW
NPENLRSPEGAGKEGHKDLEKEGSLLNG--EKQELLRSLEEEAQELPLSENQERCEAVAV
GDQDL---GQEAPSSGEGVGDEGEAEL-GLRKQDGN---------------S-AAEAWST
G-----SAEPEEQRV---PAEGASGREGVEG-----PQDLEGPPEQVGTPGLE--ASQEM
AEVPEPQREDEHEGPWGDQASLE---VTWGAETVKGGSAAGAAGAE--------------
--LGLEQEVGGLEDQEDLAHPALEEA-VQPPSGEDSLEAESAEGLEGPGQD-----HMGA
TLPNLPSR---SRDLGEPPK--GWEESEPEAPVGAEDV--SP------------------
------TDAPQPTPSGSEDAQ-DTQPVLGPTQPQ---------TPTPILEDFPGLQ----
NEGGQEA--VRGLQERTEALRKVEGEQEEF-GPEEIPED-LQEEEEE--EEESRAESEAD
ELGETLPDSTPLGLYLRSP-----SSPGWDVVGEQRPSPQ--GEARKEGWDPAV-PVP--
------------GPHSEEEEKE------ENGEEDRGQDSELSD-EFED-LQTEA------
------SFLPGVPRK--AAEPLGQVAQL-------LEPA-VWDRDGESDGFADEESGEEA
---------EEEEEGREPGSPRWGSGSTVGGLQALSSSQREDHLAPE--ALGISV-PWD-
DGLQGAMADPPVTALE----------TESQDSAEPSGSE---------------------
--------------------------------------------ESDSAPWEKE-DQVL-
-GPLETPGGLEDTGL-GGTH--SVNG-GPNLE----ESEHTSGRVVNGLEQSKGGGHRTP
EPPDGEGGTPSQK--EEGVALKTPWAGTPVHLGPSQFLKFAPR--GGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MDGCAGEESFQLWELNRR
LEAYL-GRVKALEEQNARLSVELGGLRAR-SGDASWRARADGELAALRALV---DQRWRE
KHAAEVQ---RDSLVDELERV--AGRCQQLRTARERSVEEAARGRRAVEAEQRARDWLSA
QAAELERELE----ALRAAHEEERAGLHAQ VACVPHRP-APP---RGP-PAPGPEVE-EL
ARRLGEVWRGAVRG--YQDRVAHLEASLGQARERLGCALQGAREGRLELLQLRAEHGGLQ
ERRAALEQRLEGRW--EERLRTTEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGVSSKASLSFQ---------------------------
--------------------------------------------------DPKLELHFSG
TPEGQHLGP---VLSPTSLPSPLANTLQTPVPAFLRSQEFLQAHT--PTLASTPIPAAPQ
APHPAANAEVRAQDAPHSLVPPQDG-RQQAPEPLWAEAQA-AVPADILPGPEEPGGKH--
--PGQSPEGQASLAPP--LS----PDHPSSETKDGERS-------------GSGASSRFQ
EGGKRPTWGLVEKEA----AIEDQVVSSLQQQIWQEGGELDVKEIQDSQ--DPQERETLK
ALGEEIRKSLMPLENQSHEALE----KDQESLRSLEKENLETL-KILKKENQEVLRSLGE
KDM-EIERLVEKEVTELPQPAGKEDSQTLQSLEGENQELIISLEE---------------
---------------------------------KSLRTPEKETQKPLRSQEAEDQKMWKS
LPKENWESLRSLEDESQETFKLLE--DNQEPLTSLEENEKIVRPLEKEKQELL-------
-------------------------------------TSLEE------------------
--------------------------EDEKVVRMLEKEDQEALRSLEA-DQRNVRSLEEA
DQR----------------------NVRSLEEADQK----------------------NV
RALEKENQEPLGSLED-----------ETMRPLEKEDPDPLRTLEE-DQKNV--------
-----RSLE-----------------------KENQEPLGSLEEEDQETVRPPEKEDQEL
R-----------------------------------------------------------
RTLKTLEKETQQSLR----------------------ALGEEGQMTLRLVEKVNPEPLES
LGNEQEVV-ESLEK-ENRELFKSLKAESTEPLQ-----------ST-EEDLEMLTSLEAQ
ESLWSLEETNRETVKSLEKE-ILETMGS-------VEENQETL-----------RPLGEW
NLENLRSPGEAGKEERQ---------LE--ESQESLRSLEEEARELRLPEKQQIWEKDAG
DRDE------------------------------------------EQDWNA-AAEAWSP
G-----SPEPPEQRG---PAAGDGGQGATEG-----PQGLAGPQEREAAQGVA--E---V
GEVTEAPQEEEEEPPGDGQASLE---VTWGSEMARGGS---AVGAG--------------
--QGHEQE------------PRGLEV-PVPPPGEDSLHGERARGLGGPGS----------
-----------SGDPGEHPK--DWGEWGPEAPVGAEGV--SP------------------
------ADAPQPRPLGMEEDQ-GAPLVLGAPGPT----E--P------------------
----YVA--GWGEQ-------------EE------LPEG-----------EGRAESFEAD
ELGETLPDSTPLGQYLRSP-----SSPGWDQAEEQRPSPQ--GEGSQEGWDPAV-PASRG
----------PGA------------------EEEQGQDSELSE-EFED-LETEA------
------SLPPGAPRK--AAEPLGQAAQL-------LEPA-AWDLDRESDGFADEESGEEA
----------DEEQGREPGAQRWGPGPSGGSLQVLRSPRRGAPLAPE--ALGFSV-PWD-
DGLQGAAADTPVTAVD----------TESQDSAEPSE-----------------------
--------------------------------------------ESDSAPWEKG-D----
------PSGVEDTGP---GDSHSVNG-GPGLEA---ESEHTGGRVLNGA-----------
----GGRGTPSQE--EEGVPPKTPWAGAPLHLGPSQFLKFTPR--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELAGLRAQ-SAEASWRARADDELAALRGLV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQVRLTRERIAEEAARHRRAVETEKCAQGWLSS
QAAELERELE----ALRAAHEEERASLNAQ ASCAPRGP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQSRERLGQAVQGARESRLELQQLQAERGGLQ
ERRAALEQRLESRW--QERLQATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSGSKTSLGFQ---------------------------
--------------------------------------------------DPKLELHFSG
TPEGRRLGPFLPVLSPTPLPSPLPNTLETPVPGFLKSQEFLQTHTPTPTLASTPIPTTPK
APCPATNAEIRAQDAPLSLLQPQDV-RQQAPESLWAEAKA-TFPDSILPRPEEPGGEQQG
VSAGQSPEDQASSVQL--LS----SDYPKLEANDGEPS-------------ETKGSSIFP
E-DKGQVWGLVEKDV----DIEFKAVSSLQQETQQEEGELDMKEIQDFH--GLFEKETAK
VLQEEIQEPPVCLENQ---------------------KNLEAT-KSTEKENQELLKSLEG
KDV-EEERPLDK------------DIQTLESLEKENQELMMSPEHNIERHLSLGK-DQE-
LVRAL--EEENL---------------------ELLRALEKESQQSLRSQEREDQETWSS
VVKENQEFLTPPEDENQEIFRPVEEENPEPLKSQEEEDQEIVRSPEKENQEPL-------
-------------------------------------RLLEE------------------
--------------------------DQRPLKKN-----QEPL---------RFGSPVKE
NQE----------------------SLRSVEEEDQRTVSPLEKENLEPLMSPEE-DQKIM
SPLEKKNQEPSESPE---------EDQKIVSSLEKENQESLKSSEEEDQRIG--------
-----SPFE-----------------------IENQKPLRSPEEEDQKIVSFLEKENQEP
---Q--------E---------------------EE----------------------EQ
EMLRSLDQDTQQPLS----------------------ALGE-DQMILRPPEKENPEPLKS
LGKEQEVD-WSLEK-ENRELFTSMEKESIEVVRSFETENLEPLKTARDEDLEILKSLETQ
EPLGAVEEIGKETMKALEKD-IQDTLGS-------VGENQETLRPPEKENKKPVSSLEEQ
NLETLTSLEVAEKESQRDLGEEE---MG--EKQQSLSSLEEAGQELPQSTNQPRWEDLEM
EDQAL---AQEV------------------------------AQQGQPQLNI-TGESWDS
G-----SLEPKEQRV---PAEGANGMGGSEG-----LQGQ---PEHVA-------TSQGK
PESV-------------------------------------KVGAE--------------
VGLEPEITEVGLEDPEQL---PREEM-SQPLMGEESLETESAQGLEGPRKDLEKADDLEV
ASTDLPRT---SRDPLEPSK--GLEETVPADPWVAE-P--FRAETP-------AHGG---
------SDAPPPTSPGTED--EGAQPVLGLSRPG----PSEHGPPSPIPEDVPGCQL--Q
TEGCQEA--TWGKEGRAEALGKEEGTLEEF-GPRGVPEEGLQEEE-----EESKEESEAD
ELGETLPDSTPLGLYLSSP-----VSPGWSLAGEQRPSPQ--GEAGKESWDSDV-LASKG
----------VGAPLSEEEEEEEEEEEEEEGGEEPGPDSDLSE-EFED-LGAEV------
------SHLAGIPRL--VAEPL--------------------------DGFADEEESGEE
GEE-------EEEERTEPESRRWGQGSSVGSLQALGSSPRGDFLEPE--AVGVSV-PWD-
DGLRGTVADAHVTALE----------T------EPSGLEE--------------------
--------------------------------------------ESDPVPMERE-VKVS-
-GPLETPREVEVMGP-GEGDIF-SNGQEPNLE----ESEHVNGMVVNGLEQSKEVGPGTQ
GTPDGDQELSLQE----GEAQKTPWVGTPVHLAPGRFLKFTPR--EVEGDSWSSEED---
---------------

--------------------------------------------MNSLAPTPDSQSLSLL
PLRPALSLSPSV-FLFSPKTSASRSLLLVPRVCPSSVGQTSRMEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALL---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLAREQTAEEVARNRRAVEAEKCAQAWLSS
QAAELERELE----ALRLAHEEERVGLNAQ AACTPRCP-APP---RGP-SAPAPEVE-EL
ARRLGEAWRGAV RG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
DRRAALEQRLESRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPESRRLGSLLPVLSPTSLPSPLPATLETPVPGFLKNRDLLQARS--PALASTPIPPTPQ
APSPATDAEIRAQDAPLSLLQTQGG-RQWAPEPLQAEAKV-AIPASVQPGPQEPGGKRQG
AGTGQSPEDHASLAQA--LS----PNHSSLEAKDGEAA-------------GSTVFSICQ
EEGEGQIWGLGEKET----AIEGKVVSSLQQEISEQE-DMDRKEIQDSQ--VPLEKETLT
SLGDEIQESLKTLEIQSHET---LERENQESLRAL--EDLETL-KSLEKENKEPLT----
-EV-EVVRPLEREAVGLLKPAGKEDTQTSQSLPREDQEQTKSLEGNLETFLSPGKENQE-
LVISL--QEN-S---------------------ESLTALEKEDQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RAPAAEDEEALRPLMKE
NQE----------------------PLRAPAAEDEE----------------------AL
RPLMKENQEPLRAPAV--------EDEEALRPLMKENRELLRSLEVENQEAL--------
-----RLPE-----------------------KENQELSKTLEEEDQSIVRPLETENHES
LRSL--------E---------------------EE----------------------DQ
KALKILEMETQQPQR----------------------SLGEEDQMTLRPPEEADPEPLQS
LEKDREAA-RPLEN-ENQELSKSLKEESVEAVKSLEIELLESLKSA-EGNLETLKSPETR
VPLWSLEEINHGAMTPPEKE-IQEPLGS-------AEVNQETLRLPEEENQERLRSLGAW
NLENLRSPEEVDKESQSNLAEEENLRKG--EKQESLRSLEEEGRELPQSADAQSGEDTVG
KDPEL---AQESTPGMAGVENEDK-------TEDGFAGKEEVIEQGE--RNA--REAWIP
GEGHPGSPEPKEHRG---PAEGASGKRRAGG-----LQDPEGQPQQLGTPGLQ--APQEL
PEAIEPLVEDEDVARLGDQDSPE---VMLGSEPAVGES---AAGAK--------------
--EVPGQEVGGLEDPGHL---TREEV-TEPLLEEESLEAKSVPGLEGPRKDIGEADALGA
ELSELPGK---SGDPLELPT--GWEEPEAEAILGAEEA--FPAETL-------GYDG---
------SDAPPPQPLGSEEAEEDASPVLAPPSPM----Y------TPILEDAPGSQP--Q
AEGSQEA--SWGLEGRAEALGKVESEHKEL-ASGEIPEG-LQEEE------ESREESEED
ELGETLPDSTPLGLYLRSP-----MSPKWDPAGEQSPDPQ--GETGKEGWDPTI-LASQA
----------LEAPPSGEEDGE-------EGEEERGRDSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLGQVSQLL------LEPA-AWDRDGESDGFADEEESGEE
GEEEE----EDEEEGREPGAGRWGPGSSVGSLQALSSSQRGDFMESD--SVGVNI-PWD-
DSLRGAVAGAPMTALE----------TESQESAEASGSEE--------------------
--------------------------------------------ESDPVFLERE-DKVP-
-GPLEIPSGVEGAGP-GA-DTVAVNGQGPSLEE---KSQHVNGGVINGLEQSDEVGQGML
LVPEGDRGSPFQE--EEGSALKTPWAGASVHLGSGPFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------RELE----ALRVAHE-ERGGLHAQAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAQMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLH
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPSSGSKAALSLQ---------------------------
--------------------------------------------------DPKLELHFPG
TPEGRRLGPLLSVLSPTPLSSSLPDTLETPVPNFLKRQEFLQART--PTLASTPIPPTPQ
PLRSATDAEVRVQDAPLSLLQPKVE-RQQVPEAMWAEAKV-AIPASVLPGPEEPGGKLQE
AGTGQSPEDHASLAPP--LS----PDHPSLEAKDAEPS-------------GSRVSSRFQ
EEGEGQVLGLAEKET----AVEVKGVSSLQQETQQEEGDLDMKEIQDSQ--GPLEKETLK
ALEEEIQEPLMSLGKQSHETLSSLEKENQESLRSLEEENLETL-KSPEKENQELLKSLKG
KDM-EVVRPLEKETVELLKPIGK-DPQTLQSLEKENQELMTSLEDNLETFSYPGEENQE-
LVRSL--EEENF---------------------ESLRALERENQEPLTSQ----------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------EIENQE--------
------------------------------------------------------------
----------------------------TSRPLAKENQELPRSLEDKNHETL--------
-----RLLE-----------------------KENQEPLKSLEDENQEIMRPLEKENQEP
LRSL--------E----------------------E----------------------DQ
ETMRPLEKENQEPLR----------------------PLEKENQMTLGPLEKVEPEPLKF
LGKDQEIL-RPLEK-ENQELLRSLKEESVEAMRSLETENLEPLKST-GEDLEILKSLETQ
EPLWSLEEMNQGTMKPPEKE-IQEPLVS-------VEENQETLRPLEKENQESLRSLGER
NLENLRSPEEVDKESQRYLEEEENVDKG--ENQESPRPLEEEGQELPLSADRQRREDMVV
GDQEL---DQEMPPGRAGMDSEGEAEL-DPRAQDGLAGEEESIEEGEPQLT-------AA
GEGCPGSPEPKEHRI---PAEGASGEGGAKG-----LQDPEGHPEQVGAPGLG--APWGM
SEVIEAVLKEEEEAPRDGRASPE---VTSGLETAVGVGEA-AMETE--------------
--QGPGQEALELEDPGLL---AREEV-MEPLLGEEGLEAKRVQGLEGPGKDLEEAAALEP
ELSTLPGK---SRDPPEPPR--GWEESEPEAPWGAEQV--FPAENM-------CHDG---
------SDTPQPRPLGSEEAVEDAKPVLGTPSPR----PVEPRSPTPICEDAPGPQP--L
AEGSQEA--GWELEGKAEALEKVESEQEEL-GSGGIPEG-LQEEG-----EESREESEAD
ELGETLPDSTPLGLYLRSP-----ASPKWDLAGEQRPSPQ--GETRKEGWDPVV-LASEG
----------LRPHPYPSEERE------GDEEEECGRDSDLSE-EFED-LGTEA------
------SLLPGVPGE--AAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GEEED----EEEEEGREPGAGRWGPGSSVGSLPALSGPQTGKLPESE--TMDVTV-PWD-
DGLRGVVGDAPVTALG----------TVSQDSTEPSGSEE--------------------
--------------------------------------------ESNP-SLQRE-DQVP-
-GPLETLSGEEDTGP-G-------------------------------------------
------------------------------------------------------------
---------------

------------------------------------------------------------
------------------------------------------MDGCVGEESFQLWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADDELAALRVLV---DQRWRE
KHEAEMQ---RDNLAEELEGV--TGRCQQVRLARDRTSEEVACSRRALEAEKSAQGWLST
RVAELERELE----AVRAAHEEERAHLNAQAACAPLRLAAPP---HGP-PARAPEVE-EL
ARRLGEAWRGAVRD--YQERVAHMESSLGQARERLARAMQGAREGRLELLQLQAERDGLQ
ERREALEQRLEGRW--QDRLQATEKLQLAVDALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPARSSQASRGFH---------------------------
--------------------------------------------------DPKLKLHFLG
TPEDQHLGSVLPVLSPTPLPSPMPSTLETPVTAFLKTQEFLQAQT--PTLASTPIPPMPE
APCPI-KAEVRAQDAPLSLLQTQGG-RQQGPELLWTEATV-S-----VSTSEEPGGKQL-
---SHLPKDL--------TS----SAHPVLETKDEESS-------------ESRVSSIFQ
E-DEGQIWELVEKEA----AIEVKGERSSAQETQED--GLDMEEIQDSQ--GPLQKETLE
APEE---EPLMSLKIQNHET---PGKENCNSLRSID-QTLGTL-KSS-EEKQTLLKSLEE
KDV-ESLKTLERGLPELSKPLGKEDP------GIEDDQELISPEGTLETVSSIGKENQE-
VVRSS--EENLEPSTAFEKKSHYPLGCPEEENQIVERLIEKEGQESLRSLEEEDQETYRC
LEKENGELLKSVEKEDQLVERLIEKEGQESLRSLEEEDQSIVKPLETENQESLRS-----
-----------------LDE-IQETIIPPGSKNQKQLKSLEI------------------
-------------------------EEEQRIVKPLVKE-VELLRSLEDNDQMTGS-----
------------------------------------------LETQDPQRSLEEEDQMTG
GLFQNEIQESLRSHKD----------------RDQETQDPQRSLEEEDQMTG--------
-----GLFQNEIQESLRSH---------KDRDQETQDPQRSLEEEGQGIVNYLEKEDQEF
LWSL--------EEQMVKQSLERESHKPLSSVEQKDWVT--ENLDTESQDSGKSFEEENQ
QIFRSLGKETPESLQSPEEWDQEIQRSLQQETGQIVRDVGDE-QLAVRQPELE-------
---------TPFGR-----QSPVSLEGRAETVKSSDTENTEPLKSA-EAGLQTVNAVQVQ
EPLWSPE--------------IQESLGY-------VYGNQETLRPLERENQE-LRSLGKW
NLETVDSLEGMGAAGQ-QLEAEGCLDRN--EQQESARSLAEVGQELPGSEKRQRWEDVV-
EDGAV---NQDPVLWRTGVESKEEAEP-PLTG---QSGKEEAAEDRELQLQV-TGEACSL
G-----SSEPKEQRV---PSEEDSRKGSAEA-----FQDMEGPPEQVEILEVP--VAQGM
PEVTEPLLQDEAIALTGEQDSKE---LALGSEAATRD-----------------------
---GLEQEVIGLGEPKHL---AREEA-IHPSLGEQSVEVKIAQDLEGPEKEPLEAGTLES
EIFELPKT---SRDNLEPKS---FKESEPAVGRGVEEP--S-VEPS-------DHEG---
------SAVPQPRLSETEED-EGAQAVPALPGPK----FMEPSSYIPALEDACELQP--Q
AEEIQEA--GWQLEGGSEALRKVGDEQ-EF-GLGETPEG-LQDWE------ESREESEAD
ELGETLPDSTPLGLYLRSP-----TSPKWDLAREKRLSPQ--GEAREEGWDPPVLSNP--
-----------------------------PGEEEQGPDSDLSSEEFED-LGTEA------
------SFLPGVPKG--VVDHLGQVPSV-------REPE-CWDQGGESDGFADEEESGEE
GEERE--------EEAESGAQWWGPGPSGGGFKVQDITQRGDLLEQG--SVGVSG-PWD-
DGLRGVAANSSVTALD----------TESQDSSEPSGSE---------------------
--------------------------------------------GSESVSLEGE-DHLD-
-APQEVTSTVP-----GVGDTQSPNS----------ELEHMNGRVENGLEQSEGQEGL--
-HGDQDQGRLLQEQEVEVGALKAPLVVSPVHLGPSQSLEFPLS--GVDGDSWSSEED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLAREQTAEEVARNRRAVEAEKCAQAWLSS
QAAELERELE----ALRLAHEEERVGLNAQ AACTPRCP-APP---RGP-SAPAPEVE-EL
ARRLGEAWRGAV RG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ELRAALEQRLESRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQAPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNRELLQART--PALASTPIPPTPQ
ASSPATDAEIRAQDAPLSLLQTQSG-RQRAPEPLQAEAKV-AIPASVLPGPQEPGGKRQG
AGTGQSPGDHASLAPA--LS----PEHSSLEAKDGEAA-------------GSRVFSICQ
EEGEGQIWGLGEKET----AIEGKVVSSLQQERCEEE-GMDRKEIQDSQ--VPLEKETLT
SLGEEIQESLKTLENQSHET---LERENQESPRAL--EDLETL-KSLTKENKEPLK----
-DV-EVVRPLEKEAVGLLEPAGKEDTHTSQSLPKENQELLKSLEGNLETLLSPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RS---------------
------------------------------------------------------------
-------------PAA--------EDEEALSPLTKENQELLRSLEDENQEAL--------
-----RPLE-----------------------KENQELPKTLEEEDQSIVRPLETENYES
LRSL--------E---------------------EA----------------------DQ
EALRILEKKSQQPRR----------------------SLGEEDQMTLRPPEKGNPEPLQS
LEKDQETA-RPLEN-ENQELLKSLKEESVEAVKSLEIELLESLRSA-EENLETLKSPETQ
VPLWSLEEINHETMTPPEKE-IREPLGS-------VEVNQEALRLPEEENQEPLRSLGAW
DLENLRSPEEVDKESQSNLAEEENVGKG--EDREPLRSLEEEERELPQSAGAQSGEDTAG
KDPEL---AQESPPGMAGVENEDEAEQ-NLREQDGFARKEEVVEQGE--LNA-TGQVWIP
AEGHPGSPEPEEHRG---PAEGASGKGGAEG-----FQDPEGQPQ-VGTPGLQ--APQEL
PEALQPLVEDEDVAPRGDQASPE---VTLGSEPAAGES---AAGAE--------------
--EVLGQEVGGLEDPGHL---TREEV-MEPPLEEESLEAKRVQGLEGRRKDVGEADALGA
ELSELPGK---SGDPLEPPK--GWEEPEAEAPLGAEEA--FPAETL-------G------
----------------SEEAEEDASSVLAPLSPM----Y------TPIMEDTPGSQP--Q
AEGSQEV--SWGLEGRAEALGKVESEHEEL-ASREIPEG-LQEEE-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPAGEQSPPPQ--GETGKEGWDPAV-LASQG
----------LEAPPSGGEDGE-------EGEEERGRDSDLSE-EFED-LGTEA------
------SLLPGVPRE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
VEED-------EEEGREPGAGRWGPGSSAGRLQALSSSQRGDFMESD--SVGVNV-PWD-
DGLRGAVADAPVTALE----------TESQESAEASGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEIPSGVEDADP-GA-DTVAVNGQSPSLE----KSEHVNGGVMNGLEQSEEVGQGTL
LVPEGDRGSPFQE--EEGSALKTPWAGAPVHLGSGPFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELRGHRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTAEEAARSRRAVEAEKCAQAWLST
QAAELERELG----ALRAAHEEERAGLNAQ AACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMEMSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLQATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGVSKASLGFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGPLLPVLSPTSLPSPLPATLETPVPAFLKSQEFLQART--PTLASTPIPPTPQ
APCPATDAEIRAQDAPLSLLQPQGG-RQQAPEPLWAEAKV-AIPASVLPGPEEPGGKQKE
ASIDQSPKDQASLAPP--FS----SDNSNLEGKDGEPR-------------GSRVSSMFQ
EEGEGQILGLVEKET----AIEGKVVNSLQQEIWQEEGDLDMKETQDSQ--VPLEKETLK
SLAEEIQEPLMSLENQSHET---LEKENQESLRSLE-ENFSRL-KSVEKENQELMKSLEE
KNV-EVVRPLEKETLELLKPIGKEDIQALKPPEKENQELIRSLEGNIETLLSPAKENQE-
LVSSL--E-ENL---------------------QSLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSQEVEDQETLRPPMKK
NQE----------------------SLSSLEDENQE----------------------TF
RPLEKENQEPLSSLGE--------EDQKIVRPLEKENQESLR------------------
------------------------------------------------------------
--SL--------K---------------------EE----------------------EQ
ETLRPLEKETQQSLK----------------------SLGEEDQMTLRPPERVDPEPLKS
LGKDQEII-RSPEK-ENQELLKSLKEESVEAVRSLETENLESLKSA-EENPETLKSLETQ
EPLWSLEEMNQGTMKPVEND-TQEPLRS-------VEENQETTRLLEKENQEQLRSLGAQ
DLENLRSPEEIDKESQRNMEEEEDLGKG--ENQESLRSLEEEGQELPQSANEQRWEDMVV
GNEEL---SQGSPPGRAGVENEDEAEL-DLRAQDGFAGKEEAAEQRELQLNA-MGEAWSP
GEGHPGSPEPKEQRG---PAAGASGKGGAEG-----LQDPEGQPEQGGAPGLQ--APQGM
PEVTEALLEDEDVVPGDDQASPE---VTLGSEPATGES---AVGAE--------------
--QEPEQEVLGPEDPGHL---ARKEV-IEPPPGEESLEAKSVQGLEGPGKDLEEAGALEA
ELSKLPRK---SRDPLEPPK--GWEESDLKAPWGAEEV--FPAEIS-------GHGG---
------SDAPQPRPLGSEEAEEDVQPELGLPSPT----P------TPILEDAPGPQP--Q
AEGIQEA--SWGLEGRASALGEVEGEQEEL-GSGEISEG-LQEGE------ESKEESEAD
ELGETLPDSTPLGLYLRSP-----TSSQWDPAGEQRPSPQ--GETREEGWDPVV-LASAG
----------LGAQPSEEEEEE------DGGEEECGHDSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLGQVPQLV------LEPA-AWDRDGESDGFADEEESGEE
AEE------EEEEEGREPGAGRWGPGSSVGSFQALSSSQRGDLQESE--TVGVSV-PWD-
DGLRGVVAGASVATPG----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVPLETE-DQDP-
-GLLETPSGVEDMGP-GAGDTCGVNGQGPDLE----ESEHVNGGVMNGLEQSEGVGQGKL
GAPERDRASPLRE--EEGGALKTPWAGAPLHLGPGQFLKFTQR--EGDQDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-AGDASWRARADDELAALRALV---DQRWRE
KHAAEMA---RDNLAEEVEGV--ASRCQQLRLVRERTAEEVALSRRAVEAEKCAQAWLST
QAAELERELE----ALRAAHEEERAGLNAQ AACAPRGP-APP---RGP-PAPAPEVE-EL
AQRLGEAWRGAVRG--YQERVAHMETSLGQARERLGHAMQGAREGRLELQQLQAERSGLQ
ERRAALEQRLEGRW--QERLRTTEQFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSGSKTSLSFL---------------------------
--------------------------------------------------DPKLELHFPG
TPEGRRPGPLLSVLSPTPLSSPLPGTLETPVPTFLKSQEFLQAHT--PTSASTPIPPTPQ
APCPAVDAEIRAQDAPVSLPQPRVG-RQQVPEVMWAEAKV-AVPASILPGPEEPGGQQQE
PSPSQSPEDRASLAPA--LS----HDRSSLETKGGEAS-------------GSRESSRSR
EEDEGQLWGLAEKET----VVEVKAVSSLEQETWQEEAGLDRKEIQDAQ--GPLEKEAVN
SLEEEIQKPSIPLGKQSHETVRALEKESLESLRSLEEENLETL-KILEKENQELLKSLEA
KET-EVVRSLEKETLELLKPIGKEDPQTLPSLEKENQEIMRSLEVNGETFLYPGKENQE-
LVRSL--EEENI---------------------ESLRTLEKESQEPLRCQEVENQETLRL
LAKENQEPLGSLEEEDQETSRPLGKENHESLRAPEDENHEAVRSLERENPESLSC-----
-----------------LEE-DQEAMRPPEKEN---------------------------
----------------------------QELLRSLEKENQEPLRSLEE-DQETVR-----
------------------------------------------------------------
-PL---------------------------------------------------------
--------EKENQEPLRSLEE-------------DQEEIRAL-EEDQETVTPLEKEKQE-
--------------------------------------------------AMRPLEEESQ
EPLRSLEKEKEEAMRS-----------LEN--QN--------------------------
------AV-RPLEE-ENQEPLRSLE-----------------------------------
----------------KEKE-SQESLGS-------VEGNHETLRPPGKENQESLGSLAEW
NTENLQSLEEAAKGSLRRLEEEEILEKE--ESQASLRPLEEQGQELPLSAQQQTWGDAMQ
RDQEL---DQDRPPGRAGVDSGDGAEL-ELEERDSFPAEGEVVEQGQLQLTA-TGEAWGP
GEGQPGSPEPKEQRL---PAEGAGGAGGAAG-----LQDPEEQPEQVGALGLP--AAQGM
SEVMEPELEDEDVAPGSGQASPE---VTLELERAMGRSAG--------------------
VEQGLQQEAIRLEDPGSL---AREET-TEPPLGEGGVEAKKVQGLEGPRKELEEAGTLES
EVSTQPGK---SRDPLGTPR--DWEESESGAPGKTEEP--VSAETL-------CHEA---
------SDTPQPRPLGSEGAEEDAKSLLGPPSLR----PTESCLPSLIPEDTPGPQP--L
AEGNQEA--SWGLESRAEVLGKAEGEQEDL-GSGGIPEG-LQEEG-----EESREESEAD
ELGETLPDSTPLGLYLRSP-----ASPKWDLPGEQRPSPQ--GEPGKEGWGPAV-PASKG
----------LGAQPSEEEEEE------GAE-EERGRDSELSE-EFED-LGTEA------
------SLLPGVSGEGEGEEPLSQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE---------EEEGREPGPGRWGPAPSVGSLPTLSSPQGGPLLGSE--TVGVSVPPWD-
NVPGGAAPDAPMTALE----------TESQNSTEASGSEE--------------------
--------------------------------------------ESDAAPLEPE-DQAP-
-GPLGTLSGVEDT--------LDGGGPGPSLKE---ELERVNGGVVNGLEQSEGGGQGKP
GAAGGDRGSPSE---EEGASLKAPWAGAPLHLGQGQFLKFSQR--GGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNA QAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDAEIRAQDAAVSLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIRGLVEKET----AIEGKMVSSLQQEIWEEQ-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQESPRPLE-EDLDTL-KSLEKENKELLK----
-HV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSLEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHTS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------SLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETSKSPETE
APLWPLEEINQGTMKPL--E-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEEGRELPQSADVQRWEDTVG
KDQEL---FQESPAGMAGVENEDEAEL-NLREQDGFAGKEEVVEQGE--ANA-TEEVWMP
GEGHPGSPEPKEQRG---LAEGASGKGGAEG-----LQDPKGQSQQVGAPGLQ--ALQGL
PEAIEPLVEDEDVAPRGGQASSE---VTLGSEPATGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDSEEAGALGT
ELSELPRK---SRDPWESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPRPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGRWGPGSSVGSLQALSSSQRGDFLESD--SVGVSV-PWD-
DGLRGAVAGAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPNLEG---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MESCLGEESFQMWELNRR
LEVYL-SRVKALEEQNELLSAELGGLRAQ-SADASWRAQAEDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELESV--AGRCQQQRLAREQAAEETARSRRAVEAEKCAQTWLSN
QAADLERELD----ALRAAHEEERACLNAQAACTPRRP-APP---RAP-PAPAPEVE-EL
AERLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAMQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATERFQLAVEALEQEKQGLQNQIAQVLEGRQQLAHLKMS
LSLEVATYXXXXXXXXXXXXXXXXXXXXXXXXX---------------------------
--------------------------------------------------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXX--XX----XXXXXXXXXXXXXX-------------XXXXXXXXX
XXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX-XXXXX
XXXXXXXXXXXXXXXXXXXX---XX-XXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXXPLTPIAKEEPQTLQSVE-ESQEHLKPLDDNLETFLFLGKENQEE
LLRSL--EEENL---------------------GSLRALEKESQEPLKSPEVEDQEALRP
LAKANQEPVRSQEIENQETLRLLEKENEDPLKSLKNENQETLRALEKENQKSLKY-----
-----------------LEN----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ENRD----------
---------------------------------------------------ILENMDQEP
VGSQ--------E-----------------------------------------------
-----------------------------------------EKQKTWRSLEKQTEEPLDS
LGKDDLKMLKPVEK-ETQEPLGSLKEDSVEKMESLELENPESLKFAEEEALGIRKSPEAQ
EPLWCLEEKNQETMKALEKK-IQEPLGT-------MEETQETLKLLEKENPEPLRALGEW
DLENLKSSEEVDKESQRHLEEEGTLEKG--ENEDSLRSLKNDGQGLSLSADQQRWEVAVG
AEQEL---SEDLQPGRDEVEYEDEAEL-GLREQDGLSGKEEVVGQGQLWLSA-AGEAWNT
GEGHSGRPEPEEQRA---PVEGAKGEGGTEG-----LHNPEGQPDLVGAPGLG--APQGM
LEVVGPMLKDKDMAPGSDPASLQ---VTLRSEIATGES---AVQAE--------------
--EGLEQEAVKVEDPGHL---EREEV-MKPLLGKEDLEAKKGDGLEKPGKDLQEGDAKAG
ELSKLPSE---STDPQNPRE--GWEESESEAISGTEEG--LPPEPL-------CLNG---
------TDASQPKRE------EDARPEPGTPSPK----------PTSLPEDGPGPQP--Q
TESNQVA--SWGLESSMEAPEKEEGEQ-EL-GSVGIPEG-LRERG------ESRES--AD
EL-ETXXXXXXXXXXXXSP-----ASSKWGPAEEERPSPQ--GEARQEGWDTTV-QSSEV
----------LGAHPSDEEQQD---------EEVGPSHSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLGQVPQLL------LEPA-VWDRDEESDGFADEEESGEE
EGEGN----DEEEEGRRPGAGQWGPGSFVGNLQTLSDPQRVDLVESE--TVEVNA-----
----------PITALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDLVPLERQ-DKVS-
-GPLEIPSGLEDAGP-G-PETLGVNGQGPSWEE---ESEHLNGRLVTRLEQSDEGGQGKM
GAPEADRDSPLEV--EEGGSLKAPWAGVPLRLGQSQFLKFTQR--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCAGEESFQMWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDVSWRARADDELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELESV--AGRCQQVRLARERTIEEVSCSRRALEAEKNARGWLST
QAAELERELE----ALRAAHEEERAHLNAQAACAPRRPPALA---HAS-PVRAPEVE-EL
ARRLGEVWRGAVRD--YQERVAHMESSLGQARERLGQAVRGARESRLEVQQLQADRDSLQ
ERREALEQRLEGRW--QDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENTRLQTPGRSSQASLGFP---------------------------
--------------------------------------------------DPRLKLHFLG
IPEDQHLGSVLHVLSPTSFPSPLPNTLETPVTAFLKTQEFLKART--PTLASTPIPPMSE
APRPT-NAEVRAQDVPHSLLQIQGG-RQQAPESLWAEATV-PSSTGVLPELEEPGGKQ--
--LDHFPDGPTSLAPP---L---NPHHSILEAKDRESS-------------ESRVSSIF-
QEEEGQIWELVKKEA----AIEVKVENILAQEIQES--GLDTEEIQDSQ--GPLQKETLE
ALGE---EPLMSLKIQSHET---PGKENCNS--SIEE-NPGTL-KSPEKEKQTPLKSLEE
KNV-EAEKTLENGILELSKPLGKEEP------RMEDQEL-VSPEHTLETVSFLGKENQE-
IVRS-SEELNLESLITFKEESQYPLGCPEAEDQMLERLVEKEDQSFPRSPEE-DQQAFRP
LEXXXXXXXXXXXXXXXXXXXXXXXX----------------------------X-----
-XXXXXX-----------------XXX---------XXXXX----XXXXXXX--------
--------XXX-----------X-------X-------------XXXXXXXXXXXXXXXX
XXLRDWFEEAEDQMLERLVEKESQVSLKSPEEEDQRIGKPLERENQESLRSLDE-NQETI
VPLESRNQRPLRSLEV------EEEEQRIVKPLEKVSQDSLESLEKENAQPLRYLEEDDH
DLMIKSLLEDKTHETLGSLEDRNGENFI-PPESETQGSLRPPEEEDQRIVNHLEKESQEF
LRSSETQEEEEEEEQVMERSLEGENYDPLSSVVKEEQMA-ESQLEEESQNSVKSLEDENQ
ETFWSLEKENLESLRSLAGQDQEEQK-LEQETQQPLKAVED-EQRAVSPPEKVDPELSKP
LRNDQEVI-RSLDK-ESQESLVSLNEGGMETVKSSETENIELLETV-GECLGRRKSVDTQ
EPLWSTE-VTSQTVDPLEDE-TQEPLGY-------VDENQEMLTPLERESQE-LGSLGKW
NPETVESPGGLED-SQQCLEVEEGPEWE--QHQESLRSLGEGERELPGSGNRQRWEDVV-
EDGEV---GQEASLGTTGVETEDKAEL-HLR---GQGGEEEELQ-----QDV-V------
-------GEPKEQRV---PAE---------P-----LDDLEGQPEQTGALEIP--VAQEM
PEVTE---QDEDRAQAGEQDSVE---VTFGLEA-ARAG----------------------
--LELEQEVVGLEDPRHL---AREEA-IHPFPGEESVKAKIAQSLEEPGKEPKEAGALDS
GIPELPKT---SSEALECK---GCEE--SGEGWGEEEA--S-LETS-------DHEG---
------SHAPQPRPPETEED-EGVQAALTVPG------------PIPILTDAHELQP--Q
VEGIQEA--GWQPEAGTETLGRV-DEP-EF-GRGETPEG-LQDWE------EEREDSEAD
KLGETLPDSTPLGLYLKSP-----ASPKWELAGEQRLSPQ--GEARKEGWGPAV-LAAQG
----------LSDPPDE---------------EQQGHDPDLSSEEFED-LGTEA------
------SLLSGVPKE--VADHLGQAPPV-------LQPA-CWDQGGESDGFADEEESGEE
GEEED----ADEEEGAEAGAQWWGPGPSGGGVRVQDITQRGDL-EHE--SVGDSG-LWD-
DGLRGAAAGVPITALE----------TVSQDSAEPSGPE---------------------
--------------------------------------------GSESASSEGEEDQAT-
-DHLDAPQEVTSVVP-GAGDTFDISGQGPNLV-----SEQVNGRMENGLEQAEGQVVL--
-DGDEDQGLPLQG--Q--GTLKAPLVGSPVHLGPSQSLKFTLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNAQ ASCAPRCP-APP---RGP-PAPTPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DAKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATVETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDPEIRAQGAPLSLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHDSLAPP--VS----PDHSSLEAKDGESG-------------GSREFSICQ
EEGEGQIWRLVEKET----AIEGKMVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LEREDQESPRSLE-EDVDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTVLEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------E-EDQSIVRPLETENHKS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------SLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETLKSPETE
APLWSLEEINQGTMKPL--K-IQEPLES-------VEVNQETLRLLEEENHEPLRSLGAR
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEEGRELPQSADVQRWEDTVG
KDQEL---SQESPTGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPKGQSQQVGAPGLQ--ASQRL
PEGIEPLVEDEDVAPRGDQASPE---VTLGSEPATGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPGK---SRDRGESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPRPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEED
ELGETLPDSTPLGFYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------FEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPEVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESAEE
GE-------EDEEKRREPEAGRWGPGSSVGSPQALSSSQRGDFLESD--SVGVSV-PWD-
DSLRGAVAGGPMTTLE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLGVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEGGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

MVGLLLWFHSPAPWGSRDRGCCHSLTSKGLRPGSRPSSRPPGGSMNSLAPTPDSQSLRLL
PPRPAPSLSPSVSFLFGPKSSVSRSLFLVPSVCPSSVGQTSRMEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNA QAACAPRCP-APP---RGP-PAPAPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDAEIRAQDAPVSLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHASLAPP--VS----PDHSSLEAKDGESG-------------GSRVFSICQ
EEGEGQIRGLVEKET----AIEGKMVSSLQQEIWEEQ-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENHSHET---LERENQESPRPFE-EDLDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTGLEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSLEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------EEEDQSIVRPLETENHTS
LRSL--------E---------------------EE----------------------DQ
ETLRTLERETQQPQR----------------------PLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLEN-ENQELLKSLKEESVEAVTSLETELLQSLKSAGQENLETLKSPETE
APLWSLEEINQGTMKPV--Q-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEEGRELPQSADVQRWEDTVG
KDQEL---FQESPAGMAGVENEDEAEL-NLREQDGFAGKDEVVEQGE--ANA-TEEVWIP
GEGHPGSPEPKEQRG---LAEGASGKGGAEG-----LQDPEGQSQQVEAPGLQ--APQGL
PEAIEPLVEDEDVAPRGGQASPE---VTLGSEPATGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TRKEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
EVSELPRK---SRDPWESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPRPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDPAA-LASKG
----------LEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GE-------EDEEKGREPEAGRWGPGSSVGSLQALSSSQRGDFLESD--SVGVSV-PWD-
DGLRDAVAGAPMTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLEVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEVGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQLWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADDELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELEGV--AGRCQQVRLARERTSEEVACSRRALEAEKSAQGWLSS
RVAELEREVE----AVRAAHEEERAHLNAQAACAPRRLPAPP---RGP-PAQAPEVE-EL
ARQLGEAWRGAVRD--YQERVAHMESSLGQARERLGRAVRGAREGRLELQQLQAERDGLQ
ERREALEQRLEGRW--QDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRSSQASLGFQ---------------------------
--------------------------------------------------DPKLKLRFLG
TPENQHLGSVLPVLSPTPLPSPLPDTLETPVTAFLKTQEFLQART--PTLASTPIPPMTE
APCLA-KAEVRAQDAPLSLLQTQGE-RQQAPEPLWAKATA-SVSTGVLTELEEAGGQQ--
--PGHFPEDATASAPS--LSPH----HPVLEAKDGDST-------------ESRGSSIF-
QEDEGQIWELVEKEA----AIELKVESSLAQETQED--GLHTEEIQDSQ--GPLQKETLE
ALGE---EPLMSLKIQNHET---PGKENCNSLRSVDE-NQGTL-KSPEEEKQTLLKSLEE
KDV-EVEKTLEKGVPELSKPLGKEDP------RIEDQEL-MSPEGTLETLSFIGKRNEE-
VVRS-SEEENIESLAAFKKESQHPLGCPEEEIQRVERLIEKEGQESLSSPEEEDQETDRP
LEKEN------------------EKEGQESLSSPEEEDQETYRLLEKENGE---------
------------------------------------------------------------
----------------------------------------------------PLKPV-E-
---------EEDQRVERLIEKEDQESLSSLKEEDQRIVKTLERENWESLRSLDE-NLDTV
MPLESKNQKPLKSLEA------E-EEQRIVKPLEKVSQDSIGSLEKENVELLRSLED-DQ
--ITESLLKKGTQESLESHEDRNQE---------TQDPQRFLEEEGQGIVKQLEKENQGF
LGSL------EE-EKVVKRSLERENHEPLSSVEK-DWVT-ESLLERESQDSGKSLE--GQ
EAFRCLGKEDPESLQFPEVQDQEIQRSLQQETQQTLGALGD-EQMASEPPEKVGPELLKF
LGNGQEIV-RSLEE-QNQESLVSVKETSVETAKSSDMEDIEPLKSA-DEDLEIINSAGAQ
ESLWSME-VTRETTRPLEKE-VQESLGF-------VGGNQEILRPLERGNEE-LGSLGKW
NLEAVDSPEAVEE-GRQPLGEEACLEMG--EHQEPPRSLGEVEQGLPGSGNQQKWEDRAV
ENAAA---DQGPTLGRTGIESEDEAEL-PLS---GQGEKEEDAEERELQLDA-MGEAWSL
A-----SSEPQEPRV---PSEGG----SAGA-----PQGLEGQSEQVGVLGVP--VGQGM
PEVTEPLLQ-EDVAQAGKRDPIE---LTLGSDAATRAG----------------------
--LGLEQEVAGSGGSRHL---AREEA-IHPSLGEESVEAKIAHDLEGPGKEPKEAGALES
EISELPRT---SSDVLESK---GCKQSEPVLGWAVEEA--S-VEAS-------DHEG---
------SDAPQPRPSETEGD-EGAQAALAPPGPK----LMEPCSPTPILKDAYEWQP--Q
AEGTRET--GRQLEGGSASLERVEDEQ-EF-GLGGIPEG-LQDWE------ESREESEAD
ELGETLPDSTPLGLYLRSP-----TSPKWDQAGEQRLSPQ--GEARKEGWGPAV-PAAQG
----------LSNPPGE---------------EERGHDSDLSSEEFED-LGTEA------
------SLLPGLPKE--VADHLGQVPPG-------PEPE-CWDQGGESDGFADEEESGEE
GESGEEGEEEEHEDGTESGAQWWGSGP----SKVQHVTQRGDLQEHE--SVGISG-PWD-
DGWRGAAAGISVTGLE----------TESQDSAEPSGSE---------------------
--------------------------------------------VSESVSSEGE-DQAP-
-DHLDTPQGVTNVVP-GAGDTFGISGQAPNLE-----SEHMNGRLENGLEQSEGQGVL--
-DRHQDQGHPSQQ--QEVGALKAPLLGSPVHRGPSQSLEFPLS--GADRDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQMWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDTSWRARADDELASLRILV---DQRWRE
KLEAEVQ---RDNLAEELESV--AGRCQQVRLARERTVQEAACSRRALEAEKNARGWLST
QAAELERELE----ALRAAHEEERAHLNAQ AACAPRRPPAPP---HGS-PVRAPEVE-DL
ARRLGEVWRGAV RD--YQERVAHMESSLGQARERLSQAVRGARECRLEVQQLQADRDSLQ
ERREALEQRLEGRW--QDRLQATDKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRGSQASLGFL---------------------------
--------------------------------------------------DPKLKPNFLG
IPEDQYLGSVLPALSPTSFPSPLPNTLETPVTAFLKTQEFLQART--PTLASTPIPPISE
APCPP-NAEVRAQEVPLSLLQT------QAPEPLWAEATV-PSSSAILPELEEPGGKQ--
--QGHFPDDLTSLATT---L---NPHHPTLEAKDGESS-------------ESRVSSIF-
QEDEGQIWELVEKEA----DIEVKVENSSAQKTQES--GLDTEETQDSQ--GPLQKETLK
ALGE---EPLMSLKIQNYET---AGKENCNS--STEG-HLGTL-EGPEKEKQIPLKSLEE
KNV-ESEKTLENGVPVLSELLGKEDT------RTEDQEL-MSPKGTLKRFSSLGKESQE-
VVRP-SKEGNLESWTAFKEESQHPLGFPGAEDQMLERLVEKEDQSFPRSPEEEDQEACRP
LQKENQEPLGYEEAEGQILERLIEKESQESLRSPEEEDQEAGRSLQKENQEPLGYEEAEG
QILERLIEKESQESLRSAEEEDQEACRSLQKENQEP------------------------
--------------------LGYEEAEDQILERLIEKESQESLRSPEEEDQEAGRSLQKE
NQEPLGYEEAEDQMLERLIEKESQESLKSPE-ENQRIGKPLERENQKSLRYLEE-NQETF
VPLESRNQRPLRSLEV------EEEEQRIVKPLEKVSQDSLGSLAEENVQPLRYLEEDNC
--INKSLLEDKTHKSLGSLEDRNGDSIIIPQESETQVSLRPPEEEDQRIVNHLEKESQEF
SRSS------EEEEQVMERSLEGENHESLSSVEKEDQMV-ESQLEKESQDSGKSLEDESQ
ETFGPLEKENAESLRSLAGQDQEEQK-LEQETQQTLRAVGN-EQMAVSPPEKVDPELPKP
LGNDQEIA-RSLGK-ENQESLVSLKEKGIETVKSLETEIIEPLETA-EEDLERRKSIDTQ
EPLWSTE-VARETVEPPEDE-PPGSLGS-------VDENRETLTSLEKESQE-LSSLGKW
NVET-----RVED-SQQCLQVEEGLQEE--QHQESLRE---VKQELPSSGNQQRWEDVV-
EGKAV---GQEAPLATTGVGTEDKAEL-HLR---GQGGEEEAAAEGELLQDI-VGEAWSL
G-----SSEPKEQRV---PAE---------A-----LDNLEG-----GALEVP--VAQSM
PEVTE---RDEDRAQAGEQDSIE---VTLGLEA-ARTG----------------------
--LELEQEVVGLEDPRHF---AREEA-IPPSLGEESVKAKIAQGLEGPGKEPKEAGALDS
GILELPKT---SSEALECQ---GHEESESMEGWEEEEA--S-LETS-------DHEG---
------SDAPQPRPPETEED-EGAQAALTAPGPK----LLEPCSPIPILTDAHELQP--Q
AEGIQEA--GWQPEAGSEALERVENEP-EF-GLGEIPEG-LQDWE------EGREESEAD
DLGETLPDSTPLGLYLRSP-----ASPKWDLAGEQRLSPQ--GDAGKEDWGPAV-PAAQG
----------LSGPPEE--------------EEEQGHGSDLSSEEFED-LGTEA------
------SLLPGVPKE--VADHVGQVPPV-------LQPA-CWDQGGESDGFADEEESGEE
GEEED----AD-EEGAESGAQWWGSGASGGGCKVQDIAQRGDP-VQE--SVGVSG-LWD-
DGLRGAAANVP--ALE----------MVSQDSAEPSGSE---------------------
--------------------------------------------ESESASLEGEEGQVT-
-DHLDAPQEVTSMVP-GVGDAFDIGGQSPNLD-----SEQVNGKMENGLEQAEGQVVL--
-DGDEDQELLLQG--QEVGALKVPLVASPVHLGPSQPLKFTLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQLWELNRR
LEAYL-SRVKALEEQNELLSGELRGLRAQ-SGDASWRARADDELAALRALV---DERWRE
KHAAEVE---RDNLAEELEGV--AGRCQQLLLARERTAEEAACSRRAVEAEQCAQGWLST
QAADLERELE----AMRAAHEEERAYLHAQV SCAPREPPALP---RGP-PGRVPEVE-EL
ARRLGDEWRGAV RG--YQERVAHMESSLGQARERLGRAVQGARESRRELQQLQAERSGLQ
ERRAALQRRLEGCW--QDRLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGFGSQASLDFQ---------------------------
--------------------------------------------------EPKLQLHFLG
TPEGHRLGPVLPVLSPTPLPSLLPYTLETPEPVFLKTQEFLQAHT--PTLASTPIPPTPQ
ALCPATNAEVRAQDAPLSLLQTQGG-KPQTPEPRWDEAKV-AVPASNLLGLEEPGGKH--
--TGHFPEDQAALAPS--VN----FDQPTLEAKDGEPN-------------GSRVSIIFQ
E-DEGQILELVEKEA----AIEVKVESSLGQETREEGG---LEEIQDFQ--DPLGKETLK
AVGE---EPLISLKIQGHEA---PGKENLKSLRSIE-ENSETL-KSLEKVKQTLLKPLEE
KDM-EAEGILEKEVPELPN-LGKEDL------RIVDQELVTSPEGTLETVSFLGKENQR-
VEGYP--DENIESF----KKSQHLLGYQEAVNHETLRSPTNEDQEPLRSVEEEEQVIVKP
LERENQEPLKSLEEEEQVIVKPLERENQEPLKSLEEEEQVIVRPPEKENRELLGS-----
-----------------AEE-DERIVEPLEVVNKESLGYLKE------------------
--------------------------EEQVIVKPLEKENQEPLRSLEEEEQVIVKPLERE
NQEPLNSLEEQ-VIGRLIEK-ENPEPLRSLEEEEEVIVKPLEKDNQEPLRSLEEEGQVIV
KPLERENQEPLNSLEEQPLRSLEEEEEVIVKPLEKDNQEPLRSLEEEGQVIV--------
-----KPLERENQEPLNSLEEQ---VIGRLIEKENPEPLRSLEEEEEVIVKPLEKENQEP
LRSL--------E--------------------EEEQVT--EMLKKEDQYSLKSLGDEDQ
VIFRPLEKENQESLRSLGEQGQEIQRFLEQAAPQTLSAVEKEDQMAVRSPEKVNPGLLQS
LGNNQEIV-SFLEK-ENQELLTPLK-ESIETVQSLETEDLEPLKIIGEKDLEILNSLEAQ
KSLWSVGEMNRETMKPLENE-IQKPLEY-------VEENEETPHPLEKENQD-LRSLHKW
DLETVQSPEWAEKESQQHLEVEECLEVG--ENLELLRSLEE-GQELLMSAHQLRWKDMV-
EDQAL---GQDLPLGRTGMDSEDQEKL-YLSG---QGGKEEVKEQGGLQLDA-TGEAWRP
G-----SPEPKERRI---PAEEASRKE--------------DQLEQMGTPGLP--TAQGK
PKVTELVLEDEDIARGGDHASLE---VTLGSEATRAG-----------------------
--LGLTQEVVGLGDPGHL---AREEA-IQPPLREECLEVERVQDLEGPGKDRKEAE----
-FLEWPKT---SRDPLEPPK--HCEVPEPVASWGEEEA--LAAEIS-------GHEG---
------SDSSPSRPPETEEN-EVAEPELGLPDSR----PTESHLPTLVLEDALGLQP--Q
GEGSREA--GWGQAE---ALEGVEAEQ-QF-GPGEDSEA-LQDW------EESKEDSEAD
ELGETLPDSTPLGFYLSSP-----TSPPWDLAGQQRLSPQ--GEATKKGWDPAV-LGPQG
----------LGD-----------------VEEEQGHDSDLSE-EFED-LGTET------
------SLLPGVPRE--VAEPLGQVPPL-------LESA-CWDQGGESDGFADEEESGEE
GED------EEHKAGMELGVQWWGPGPTVGGLQAQDRFQRGNIQEHE--AVGVSG-PWD-
DSLSGAEADVSVTALE----------IKSQDAAEPSGSE---------------------
--------------------------------------------ESDSVSLEME-DQMS-
-GREV-----KGIGT-WVGSTSGINGQGPNLE----ESEHVNGRVINGLELSEGQGTH--
--GDQDEGLPLQE--EEGSTLKTPWVGSPVHLVPSQFPKYPPR--EADRDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLAREQTAEEVARNRRAVEAEKCAQVWLSS
QAAELERELE----ALRLAHEEERVGLNAQ AACTPRCP-APP---RGP-SAPAPEVE-EL
ARRLGEAWRGAV RG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLESRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPTTLETPVPAFLKNRELLQART--PALASTPIPPTPQ
APSPAADAEIRAQDAPLSLLQAQGG-RQWAPEPLQAEAKV-AIPASILPGAQEPGGKRQE
AGTGQSPEDQASLAPT--LN----PDHSSLEAKDGEAT-------------GSRVFSICQ
EEGEGQIWGLGEKET----AIEGKVVSTLQQEICEEE-DMDRKEIQDSQ--VPLEKETLT
SLGEEIQESLKTLENQSHET---LERENQESPRAL--EDLEAL-KSLEKETKEPLK----
-HV-EVVRPLEKEAVGLLKPTGKEDTQISQSLPKENQELMKSLEGNLETFLSPGKENQE-
LVSSL--QEN-L---------------------ESLTALEKENQQPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RS---------------
------------------------------------------------------------
-------------PAV--------EDEEALRPLTKENQELLRSLEDENQEAL--------
-----RPPE-----------------------KGNQEPPKTLEEEDESIVRPIETENHES
VRSL--------E---------------------EE----------------------DQ
EALRILEKETQQPQK----------------------SLGEEDQMTLRPPEKGDPEPLQS
LEKDQEIA-TPLEN-ENQELLKSLKEESVEAVKSVEIELLESLKSA-EENLETLKSPETQ
VPLWSLEEINHGTMTPPEKE-IQEPLGP-------VEVNQETLRLPEEENQECLRSLGAW
NMENLRSPEEVDKESQSSLAEEENLGKG--ENQESLRSLEEEGRELPQSADAQSREDTVG
KDPEL---AQESPPGMAGVENEDEAEQ-NLREQDGFAGKEEVVAQGE--LNA-TGEAWVP
GEGHPGSPEPKEHRG---AAEGASGKGGAEG-----LQDPEGQPQQVGTPGLQ--APQEL
PEAIEPLVEDEDVALRGDQASPE---VMLGSEPAMGES---ASGTE--------------
--EVPGQEVGGLEDPGHL---TREEV-MEPPLEEESLKAKRVQDLEGPRKVVGEADALGA
EFSELPGK---SGDPLEPPK--GWEELEAEAPLGAEEA--FPAETL-------GHNR---
------SDAPPPRPLGSEEAEEDASPVLAPPSPM----Y------TPILEDAPGSQP--Q
AEGSQEA--SWELEGRAEALGKVESEHEEL-ASGEIPEG-LQEEE-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPAGEQSPPPQ--GETGKEGWDPAV-LASQG
----------LEAPPSGEEDGE-------EGEEERGHDSDLSE-EFED-LGTEA------
------SLLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESGEE
GEEE-------LEEGREPGAGRWGPGSSVGSLQALSSSQRGDFMESD--SVGVSV-PWD-
DGLRGAVAAAPMTALE----------TESQESAEASGSEE--------------------
--------------------------------------------ESDPVSLERE-DKDP-
-GPLEIPSGVEDADP-GA-DTVTVNGQGPSLE----KSQHVNGGVMNGLEQSEEVGQGTL
LVPEGDRGSPFQE--EEASALKTPWAGAPVHLGSGPFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQLWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KYAAEVE---RDNLAEELEGV--AGRCQQLRLARERASEEAARSRRAVEAEQCARGWLSA
QAAELERELD----ALRAAHDEERASLNAQAACAPRVP-ARP---RGP-PAPAPEVE-EL
ARRLGDAWRGAVRG--YQERVAHMEMSLGQARERLGRAVQGAREGRLELQQLQTERSGLQ
ERRETLEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGSSKASLSFP---------------------------
--------------------------------------------------DPKPELHFPG
TPEGRRLGPLLPVLSPTALPSPLPNALETPVPAFLKSHECLQAPT--PALASTPIPPTPQ
ASCPATNVAARAQDAPVSSVQPQGE-SQQAPELVWAEARG-AVPASILPGPQEPGGKQPE
ASTSQSPENQSSLAPP--LG----LDHPSLEAKDGEPS-------------GSIASSRFQ
EESEGQVWGLVETEA----ATEVHVVRNVQQKTWPEEGDLDMKEIQDR---DPLEKETLK
TGGIEIPEPQMSLENQSHEA---LEKEDQESLRSLEEENLETR-KDLENKNPELLKSLEE
KDL-QLERPLEKEAPELPRLIGKEDSQTLQSLEKENQELMMSLEGNLETVLFAGKEYQE-
SVKSP--EEEKL---------------------ESLGALKEENQQPLGSEEPEDQGSWGS
LPKENQEFLGALENENQETFRPPGKENQEPPKALEEEDQKIVRPLEKENQEPL-------
-------------------------------------RYLEE------------------
--------------------------EDQKTVRPLEKENQEPLRYLEEEDGKTLRPLEKE
NQE----------------------PLRYLEEEDGK----------------------TV
RPLEKENQEPLRYLEE-------EEDQKTVRPLEKEIQEPLWSLEEEDQKVV--------
-----IPLE-----------------------KETQQPQSSLEKDQGSIMPP-EKEDQE-
-CSS--------Q---------------------EE----------------------DQ
ETLRHLEKETQQPSA----------------------ALGEEEQMTWRSLEKVDPESLKS
LGKDQEIV-RSLEK-ENQELSKSPKEESGEAMGSLETKNLEPFESAEEENLEILKCQETQ
EPLWSLEETNKETIKPVEKK-IQEPLAS-------AEENQETPRPLEKETQEPLRSLGEW
DLENPGFPKEAEKESPRDQEEEERLEKG--ETQESLKSLGEEGQEPPWST-NQRWEDRAV
GDQAL---SQEAPPGRLGVGSEDEAEP-DLREQDGEEEVAQ--------PEA-PEPNVTG
GTGSPGSPGPGEQSV---PAEGARGKGDTEG-----LQDAAGPAEPVGAPGLG--ASPGK
PGGTEPPRADEGEASE---GDLE---VAWGPETARGEA---AVGAK--------------
--LAPEQEVMGLEDPGHQ---AGQEG-TWPPLGEEGSGAERAQLFG---KDREE------
--ADVLGT---SRDPPEPPK--DLEGSESEAPWGAEEG--SPVDTS-------GRGT---
---------FQPQAPGSEES-EDVPPALGPPSPR----PPEPWRPTPVLGDAPGPQP--Q
DEGSLAA--GWGLEGGAEALRKVQGEQEEL-GPGDVSED-PQEEG-----EESREESEAD
ELGETLPDSTPLGLYLQSP-----ASPRWDMAGEQRPSPL--GEARKEGWDPTA-LVSKG
----------PGAQPSEEEEEE-------EEEEGQGQDSDLSE-EFED-LVTEA------
------ALLPGDPRE--LAEPLGQVPQM-------PKPE-VWDGDGESDGFADEEEGGEE
GEEEE----EEEEEGRGPGAPRWGPGASVSSLQTLSSSQRGDLLEPE--TVGVSV-PWD-
HGLKA-----SVTALE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDSAPLERE-DPDS-
-GPLQTPRGEEAPGP-RAGDALSVNGGDHSLEE---EPEDGDGRVMNGLQPSQGTGQGTP
EAPDGDREVPLQE--EEGVALKTPRAGAPVHLGPGRFLKFAPR--EGEGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQLWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADDELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELEGV--AGRCQQMRLARERTSEEAACSRRTLEAEKSAQGWLSS
RAAELERELE----ALRAAHEEERAHLNAQAACAPRRLPAPP---RGP-PARAPEVE-EL
ARRLGEAWRGAVRD--YQERVAHMESSLGQARERLGRAVRGAREGRLELQQLQAERDGLQ
ERREALEQRLEGRW--QDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRSSQASLGFQ---------------------------
--------------------------------------------------DPKLKLHFLG
IPEDQHLGSVIPALSPTPLPSPLPGTLETPVTAFLKTQEFLQART--PTLASTPIPAMAE
APCPT-KAEVRAQDAPLSLLQTQGG-EQQGPEPLWAEAAG-SVSTGVLPELEEPGSKQ--
--PGHFPEDPASSVPS--LT----LHHPVLEAKDGEPS-------------ESRVSSIF-
QEDEGQIWEVVEKEA----AIEVKLESSLAQETQED--GLDMEEIQDSQ--GPLQKETLE
ALGE---ETLMSRKIQSHET---PGKENSSSLRSIDA-NLGTL-KNPEKEKQTLLKSLEE
KDV-EEDKTLEKEVPELSKPLGKEDP------RVEEQEL-MSLEGTLETVSFTGKENHE-
VARS-SDEENLESLTALKKESQHPLGYPEEEDQRVERLIEKECLESLRSLDKEDQEAYRP
LEKENQEPLKFVEEEDQMVERLIEKECLESLRSLDEEDQETYRPLEKENQEPLKFVEEED
QMVERLIEK---------------------------------------------------
-------------------------------------ECLESLRSLDEEDQETDRPLEKE
NQELLKSVEEEDQMVERLIEKECLESLRSLDEEDQRTVKPLERENQESLRSFDE-NQETV
IPLES--EKPLKSLEE------E-EEQRIVKPLEKVSQGSMGSLEKENVELLRSLEDNDQ
--MTGGLLKEETQESLWSPEERNQE---------TQDPQRSLEEEDQRIMNHLEKDNRGF
LGSL------EEEEQVVKGSLGRENHEPLSCVEKEDWTT-ESLLDQGSQDSGKSLEDENH
ETFRALKEENPESLQPLEEQDQEIQRSLQQETQQALRSVGD-DQMAVRPPEKVGPEF---
---DQEIA-RALEN-QDQESLVSLEERSVEAVKSSETEDLDPLKNA-TGDLEIMSSIDAQ
EPLWSTE-VSRESTQPLENE-IQERLEY-------VDGHQKTLRPLEGEAQD-LSSLGKW
DLEAVESPEGMEE-GRQQLQVEACLEME--EHQESLRSLEEVGQELPGSGDPQRWEDVVV
ENGAA---EQDPPLGRTGVESEDEAEL-PLS---GQDGKEDAAEERERQLDVTPGEAWGL
G-----SCAPTEQRV-----------------------DLEGQPEQMGALEVP--VAQGM
AEATEPLLQDEDGAQAGGHDSIE---ATLGSGVATRAA----------------------
--LELEQDVVGLEEPRHL---ARGEA-IHPSLGEESVEAKVAQDFEEPEKEPKEVGAVES
EIFELPKT----SDALESK---GCQESEPVVSWGVEEA--S-VGTS-------DHEG---
------SDAPQPRPSETEED-GGTQATLAPPG---------PCSPIPALEDACELQP--Q
AEGIQEA--GWQLEGVSEVLGKVEDEQ-EF-GIGETPEG-LQDWE------DSREESEAD
ALGETLPDSTPLGLYLRSP-----TSPKWDLDGEPRLSPQ--GEAGKEGWDPAV-LTSQG
----------LSNPPGE---------------EEQGQDSDLSSEEFED-LGTEA------
------SLLPGVPQE--AADHLGQVPPV-------LEPE-CWDQGGESDGFADEEESGEE
GEE-----EGEHEGGAESGPQWWGPGPSGGGFKVQDTTQRGDLREHE--SVGVSG-PWD-
DGLRGATANISVAALE----------TESQDSAEPSGSE---------------------
--------------------------------------------GSESVSSEGE-DQVP-
-DHLDAPQEVTSMVP-GAGDTFAIGGQGPSLE-----SEHVNGRMENGLEQAEEQGVL--
-DGGQDQGLLLQE--QEGGTLKAPLVGSPVHLDPSHSLEFPLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCMGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SADTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEELEGV--AGRCQQLRLARERTTEEVARSRRAVEAEKCARAWLIS
QA A-------------------------------------------------------RL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGCGSKTSLSFQ---------------------------
--------------------------------------------------DPKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQART--PTLASTPISPTPQ
APSPAADAEIRAQDAPVSLLQTQGG-RKQAPEPLRAEASV-AIPASILPGPEEPGGQRQE
ASTGQSPEDHASLAPP--LS----PDHSSLEAKDGESG-------------GSRVFSICQ
GEGEGQIWGLVEKET----AIEGKVVSSLQQEIGEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LERENQECPRSLE-EDLETL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGQLKLIGKEDTQTLQSLQEENQELMNSLEGNLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLAALEKESQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVRDEEALRPLTKE
NQE----------------------PLRSLEDENQE----------------------AF
RSLEKENQEPLKTL----------------------------------------------
------------------------------------------EKEDQSIVRPLETENHKS
LRSL--------E---------------------EQ----------------------DQ
ETLRTLEKETQQRRR----------------------SLGEEDQMTLRPPEKADPEPLKS
L--DQEIA-RPFEN-KNQEVLKSLKEESVEAIKSLEAEILESLKSAGQENLETLKSPETQ
APLWSPEEINQGTMKPLEKE-IQEPLES-------VEVNQETLRLLEEENQESLRSLGAW
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEEGREVPQSADVQRWEDTVG
KDQEL---AQESPPGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--LNA-TEEVWIP
GEGHPESPEPKEQRG---LVEGASGKGGAEG-----LQDPEGQSQQVGAPGLQ--APQGL
PEAIEPLVEDEDVAPGGDQASPE---VMLGSEPATGES---AAGAE--------------
--PGPGQEMGGLEDPGYL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGT
EFSELPGK---SRDPWEPPK-G-REESEAEAPGGAEEA--FPAETL-------GHAG---
------SDAPPPWPLGSEEAEEDVPPVLVPPSPM----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQRRAEALEKVESEQEEL-GSGEIPEG-L-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

------------------------------------------------------------
------------------------------------------MEGCMREESVQMWELNRR
LEAYL-SRVKSLEEQNERLRLEIGSLREL-PGEPSWRSQAEEELNSLRALL---DQRWSE
KHAAEVA---RDNLLEEVEGV--ASRCQQQRLARERAKEQMAESRRVLEAEKWAGVCLGN
QAAELEKELE----ALVAAHEQERAGISAQVARR-LCPETFR---RAPDNAPAPDVQ-DL
ARTFGEAWRGAVEG--YQARVACMEASLGQARERLGQAMQGTREGQREVQRLDVERAALQ
GRREMLEQRLEGQW--QQQQESGEKFQLAVEALEQEKQDLHNQIAQVLEDRQQLMHLKMS
LSLEVATYRTLLEAESSRLHTSNIDSKVTVIFP---------------------------
--------------------------------------------------DPKVELCTPV
TPEIRRPGPRPPVLSPTPLP--MVDTPRTPMPTFLKSQGFVPTQT--PTLASTPIPHISQ
APTQ-ALGELQAQVVPAYLLQAKDSEHLTAPKLPWAKAKV-GIGMGSSLGSEEPGIEKQQ
VPSFPCPDELMERVEEGKIVLATDSGVDPLKVKAGEEKREELSGL--------REPSKYQ
KKEEKEIQGVAQKEE----E-VKETIQRLEGEALDREEIQDCQEIQETL-----------
RFPE-----------KFQETLGIMGGEIKETLNLQGEETQETQ-KLPSEDSGD----PEG
GEIQETQKLPSEDSLEA-QILSREEIQETQK---------LPSEDSLEAQILPGEEIQE-
S----------------------------------------------RLPSEDSLEAQIL
PGEEIQETQKLPSEDSLEAQILPGEEIQETQKLPSEDSLEAQILSREEIQE---------
------------------------TQKLP-------------------------------
---------------------SEDSLEAQILVRPGDP-----------EASKSWRPPGEE
IHETVRTPWKEIHETQKLPSEENQKLLSFPGEEKQEILKSPEKET---LRSLGKENGKIL
SSPKEGNGE---------------------------------------------------
-------------------------------RG------ESPEENKQETVSALE-EEKQ-
------------------------------------------------------------
-----------E------------------TR-----GSPEDIQALLGPPEEENQEILKP
-----------------------LK-----------------------------------
------------------EE-IQEIVCFSEEGNQEWEVMQEILGLPEREMQETLRTPDEG
ILEMEENQE---------ILEEGKGDLGRKESQETLQSLEEESALQ-------KPEDVAR
MGQE----LDEKGPCEIGKDHEETAKL-KPGEQSGLERNWEVVEGTGWKYGG-PAESWHA
GEEELGSQESEEQEF---PTKETIEEGMTKD-----LHMESG---RMEPS----------
---------------GKDGVAPGDDPLL------DREE----------------------
---VRN--------PEHL---NWEEGLSEPHYKEVIRVQE-L--ERETRKGVQETDELNQ
QSNKLLMENGSHPH--FEPR--DIEEPEQGKSLGMGEXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X
XXXXXXXXXGKVDVQDSSAA-----------------------F------QEEVEESEED
DLSETLPDSTPLGLYSRDP-----ESPSWGIIGKEHPSPQ--E-EHTDTWDPPP-KHAEV
----------SKAQPYEGEEE--------VEEEEGAPDSEISE-EFED-LAADA------
------SLLPRGPGG--LVDTMGHGSELV------LDPP-TWDRDGESDGFADEEESAED
EED--------DDDERSEGIRHWKLGPSLGQ--SYHQEEK--PKEER--DRNADA-PSD-
VGEREGAEHPSPVVLEIAQG------TKALDSDRQSDSEEE-------------------
---------------------------------------------HDLTSLDKE-DQASD
GDLIEIPCRVDDGSL------ESLSGGGPSLDQ----PDDIRGEILNGLGKLEEADQRKL
WDLEREGGS---P--GEELSSHTQWSGGPLILEQRPFLKFTQS-KEEDGDSWSSGDE---
---------------

MVGLLLWFHSPAHWGSRDRGCCHSLTSKGLRPGSRPFSRPPGGSMNSLAPTPDSQSLRLL
PPRPTPSLSPSVSFLFGPKSSASRSLFLVPRVCPSSVGQTNRMEGCMGEESFQMWELNRR
LEAYL-GRVKALEEQNELLSAELGGLRAQ-SGDTSWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLVEELEGV--VGRCQQLRLARERTAEEVARNRRAVEAEKCARAWLSR
QAAELERELE----ALRLAHEEERIGLNAQ ASCAPRCP-APP---RGP-PAPTPEVE-EL
ARRLGEAWRGAVRG--YQERVAHMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGGGSKTSLSFP---------------------------
--------------------------------------------------DAKLELQFPG
TPEGRRLGSLLPVLSPTSLPSPLPATVETPVPAFLKNQEFLQART--PTLASTPIPPTPQ
APSLATDPEIRAQGAPLSLLQAQGG-RKQAPEPLQAEAKV-AIPASVLPGPEEPGGQWQE
AGTGQSPEDHDSLAPP--VS----PDHSSLEAKDGESG-------------GSREFSICQ
EEGEGQIWRLVEKET----AIEGKMVSSLQQEIWEEE-DLNRKEIQDSQ--VPLEKETLK
SLGEEIQESLKTLENQSHET---LEREDQESPRSLE-EDVDTL-KSLEKENKELLK----
-DV-EVVRPLEKEAVGLLKPIGKEDTQTLQPLQKENQELMKSLEGKLETFLFPGKENQE-
LVSSL--QEN-L---------------------ESLTVLEKENQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RSPEVEDEEALRSLTKV
NQE----------------------PLRSLEDENQE----------------------AF
RPLEKENQEPLNTL----------------------------------------------
------------------------------------------E-EDQSIVRPLETENHKS
LRSL--------E---------------------EE----------------------DQ
ETLRTLEKETQQPQR----------------------SLGEEDQMTLRPPEKVDPEPLKS
F--DQEIA-RPLES-ENQELLKSLKEESVEAVKSLETELLQSLKSAGQENLETLKS-ETE
APLWSLEEINQGTVKPL--K-IQEPLES-------VEVNQETLRLLEEENQEPLRSLGAR
NLENLRSPEEVDKESQRNLEEEENLGKG--ENQESLRSLEEEGRELPQSADVQRWEDTVG
KDQEL---SQESPTGMAGVENEDEAEL-NLREQDGFTGKEEVVEQGE--ANA-TEEVWIP
GEGHPESPEPKEQRG---LAEGASGKGGAEG-----LQDPKGQSQQVGAPGLQ--ASQRL
PEGIEPLVEDEDVAPRGDQASPE---VTLGSEPATGES---AVGAE--------------
--PGPRQEVGGLEDSGHL---TREEV-MEPPLEEESLEAKRVQGLEGPRKDPEEAGALGT
ELSELPGK---SRDRGESPK-G-WEESEAEAPREAEEA--FPAETL-------GHDG---
------SDAPPPRPLGSEEAEKDVPPVLVSPSPT----Y------TPILEDAPGPQP--Q
AEGSQEA--SWGVQGRAEALGKVESEQEEL-GSGEIPKG-LQEEG-----EESREESEED
ELGETLPDSTPLGLYLRSP-----TSPKWDPTGEQRPPPQ--GKTGKEGWDAAA-LASKG
----------FEAPPSEEEEGE-------EGEEECGRDSDLSE-EFED-LGTEA------
------SFLPGVPGE--VAEPLGQVPQLL------LEPA-AWDRDGESDGFADEEESAEE
GE-------EDEEKGREPEAGRWGPGSSVGSPQALSSSQRGDFLESD--SVGVSV-PWD-
DSLRGAVAGGPMTTLE----------TESQDSAEPSGSEE--------------------
--------------------------------------------ESDPVSLERE-DKVP-
-GPLGVPGGMEDSGP-GA-DIIGVNGQGPNLEE---KSQHVNGGVMNGLEQSEEGGQGTL
LVPEEDRGSPFQE--EEGSALKTSWAGAPVHLGQGQFLKFTQR--EGDRESWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCVGEESFQMWELNRR
LEAYL-TRVKTLEEQNQLLSAELGGLRAQ-SGDASWRARADEELAALRVLV---DQRWRE
KHEAEVQ---RDNLAEELESV--AGRCQQVRLARERTIEEAACSRRALEAEKNARGWLST
QAAELERELE----ALRAAHEEERAHLNAQAACAPRRPPAPA---HAS-PVQAPEVE-EL
ARRLGEVWRGAVRD--YQERVAHMESSLGQARERLGQAVRGVRESRLEVQQLQADRDSLQ
ERREALEQRLEGRW--QDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGRCSQASLGFP---------------------------
--------------------------------------------------DPKLKLHFLG
IPEDQHLGSVLPVLSPTSFSSPLPNTLETPVTAFLKTQEFLKART--PTLASTPIPPMSE
APCPK-NAEVRAQDVPHSLLQTQGG-RQQAPEPLWAEATV-PSSTGVLPELEEPGGEQ--
--PDHFPDDPTPLAPP--LL---NPHHSILEDKDRESS-------------ESRVSSIF-
QEEEGQIWELVKKEA----ATEVKVENSLAQEIQES--GLDTEEIQDSQ--GPLQKETLE
ALGD---EPLMSLKTQNHET---PGKENCNS--SIEE-NLGTV-KSPEKEKQTLLKSLEE
KNV-EAEKTLENGVLELSKPLGEEEL------RMEDQEL-MSPEHTLETVSFLGKENQ--
VVRS-SEERNLESLITFKEESQYPLGGPEAEDQMLERLVEKEDQRFPRSPEE-DQQAFRP
LEKENQEPQRFEEAEDQMLERLIEKESQESLKSPEEEDQQAFRPLEKENQEPQRFKEAED
QVLERLIEKESQESLKSPEEEDQQAFRPLEKENQEPXRFXEAEDQVLERLIEKESXESLK
SPEEEDQQAFRPLEKENQEPXRFEEAEDQVLERLIEKESRESLKSPEEEDQQAFRPLEKE
HKEPQRFEEAEDQMLERLIEKESQESLKSPEEEDQRSGKPLEKENQESLRSLDE-NQETI
VPLESRNQRPLRSLEV------EEEEQRIVKPLEKVSQVSLESLEKENVQSPRYLDEDDH
--MIKSLLEDKPHETLGSLEDRNGENFI-PPENETQGSLRPPEEEDQRIVNHLEKESQEF
LRSPEAE---EEEEQVMARSLEGENHDPLSSVVKEERMAAESKLEKESQDSGKSLEDESQ
ETFGSLEKENLESLSSLAGQDQEEQK-LEQETQQPPRAIED-EQMAANPPEKVDPELPKP
LRNDQEVV-RSLDK-ENEESLGSLNEGGMGTVKSSETENIESLETV-EECLGRGKSVDTR
EPLWSTE-VTSETIEPLEDE-AQEPLGC-------VDENQDALTPLERESQE-LRSLGKW
NPETVESPGGVED-SQQCLEVEEGPERE--QHQESLRSLGEVEWELPGSGSQQRWEDVV-
EDGEV---DQEASLGATGVETEDKAEL-HLR---GQGGEEEAAEEGELLQDA-VGEAWSL
G-----SSEPKEQRV---PAE---------P-----LDDLEGQPEQTGALEVP--VAQGM
PEATE---QDEDRAQAGEQDSVE---VTLGLEA-ARAG----------------------
--LELEQEVVGLEDPRHF---AREES-IHPSLGEESVKAKIAQGLEEPGKEPKEAGALDS
GIPELPKT---SSETLECK---GWEE--SGEGWGEEEA--L-LETS-------DHEG---
------SHAPQPRSPKTEED-VGVQAALTVPGPK----LLEPCSPIPILTDAHELQP--Q
AEGIQEA--GWQPEAGTEALGRVEDEP-EF-GRGEIPEG-LQDWE------EGREDSEAD
ELGETLPDSTPLGLYLKSP-----ASPKWEQAGEQRLFPQ--GEARKEGWSPAV-LAAQG
----------LSDPPEE---------------EQQGHDSDLSSEEFED-LGTEA------
------SLLPGLPKE--VSNHLGQAPPV-------LQPA-CWDQGGESDGFADEEESGEE
GEEED----ADEEEGAESGAQWWGPGPSGGGVKVQDITQRGDL-EHE--SVGDSG-LWD-
DGLSGAAANVPVTALE----------TVSQDSAEPSGSE---------------------
--------------------------------------------GSESASLEGEEGQAI-
-DHLDAPQEVTSMVP-GAGDTFDISGQGPSLE-----SEQVNGRMENGLEQAEGQVLL--
-DGDKDQGLPLQG--Q--ATLKAPLVGSPVRLGPSQPLKFTLS--GVDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLGAELGGLRAQ-TGDASWRARADEELAALRALV---EQRWRE
KHAAEVA---RDNLADEVEGV--ASQCQQQRLARERAAAEAARSRRAAEAEKCAQARLGS
RVAELERELK----AVYAAHEEER AGLCARP-LVPSRP-AAP---RGP-PAPAPELE-EL
ARRLGDAWRGAVRD--YQERVARMETSLGQARERLSRAVQGAREGRLELQQLQAERGGLQ
ERRAALEQRLEGRW--QERLRATEKFQLAVDALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSGSNPSLGFQ---------------------------
--------------------------------------------------DPKLELHFPG
TPEGQHLGPLLSALSPTSLSLPLPDTLETPMPGFLKSQKFLQART--PTLASTPIPPTLQ
APCSVRDAKIRAQDAPPSLLQPQIG-RQQVPEAIQAKAKV-AIPTSILPGPEEPGGEQRE
TSTGQSSEDATSLASS--LS----PYHSSLEAKGRELS-------------GSGMASRFQ
EEGKGQIRKLAEEET----AIEVKMVNSLQQETQQEE-GLNMQEIQDSQ--GPLERETLK
SVEEKIQEPSMSLEKQSHETLRSLEREYLESLRSLEEDKLDRP-NSLEKENQELLMSLEE
EDA-EVVRPLEKKTLGLVKSVGKEDPQMLQSLEKENREIMRSLEDGLETFLYPEKENQE-
LVRSL--EEN-F---------------------ESVRDLEKENQEPL-------------
------------------------------------------------------------
-------------------------------------WSLED------------------
--------------------------EKQETLRPLEKDNQEPLRSLEDENQETLRSLEKE
NQ----------------------------------------------------------
------------------------------------------------------------
------------------------------------KSLRPLEEEDQETMRPLEEENQEQ
VKSL--------E--------------------EEE----------------------DQ
ETLRPLEKENQEPMK----------------------SLEGEDQGTLRPLEKENQEPVKS
LEEDLATL-RPLEKNEDQQLLRFLKEESVEAMRSLETENLEQLQSA-RKDLEILKPLKTQ
ESLWSLEETNQETMKPLEKE-SQEPLES-------VEEHQETLRPLEKENPESLNSLGEG
NLEHLRPPEELGKESQRYLAEEETPEHM--ENPESPRSLKEEGQELPLSATQQGWEDMVG
G-QEV---DQKMLPGRAAVGQEAEGKL-DLREWDGSG--KESVGHGELQLAA-TGEVWNP
GKGHPGCPEPKEQRI---PVKGVGGEGGTEG-----FQDLEVQPEQVGAPGLQ--APQGM
SEARQLVSEGGDESPEGGQTSLE---VTLGLETAVEDS---APGSR--------------
--QVPEQEVVGLEDPGHL---AREEV-MVPPIGE-ELEAERMQGLEGPFLGSKEAVALDP
EPSTLLRK---STDPLAPPQ--CWEEVEPEAPWGAEVG--LPVETQ-------GPSHSGN
-----SGGTPQSRPLGSEEAGEDADLMLGPLSPR----PTEPRVPTPIPGDAPGLQL--L
AEGSQEA--GWGLEGRAEALGRVEGEQEEL-GSEGSPED-LQEEG------KNREDSEAD
ELGETLPDSTPLGLYLRSP-----ASPKWDQVGEQRPSPQ--GQAGKEGWDPSA-LASQL
---------------GEEE---------EEEGEECGQDSDLSG-EFED-LETEG------
------SVLPGVPGE--AAERPGQVPQLL------LEPA-AWDRDRESDGFADEEESGEE
GE---------EEEGRESEAGHWGPGLAVGTLPGPGGPQRGSFLGSE--SVDVSV-PWD-
DGSRGMAAASCVSVLE----------TESRDSTEPSGSDE--------------------
--------------------------------------------EADPVPLERG-DQVP-
-GPLGTLTGVEEPGL-GGGDGLGVNSQGPSLKE---ELEHMNGEVVNGLQQSEGGGQGEL
GGPEGSQGSPLEE--DERGALKTPWAGPALHLGPSQFLKFSQR--EGDVDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-SRDTSWRARAEDELAALRALV---DQSWRE
KHAAEVA---RDNLAEELEGV--AGRCQQQRLARERAAEEVARSRRAVEAEKRSQAWLST
QVADLEREVE----ALRAAHEEERALLNA QAACAPRGP-PPP---RGA-PAPAPEVE-EL
AQRLGEAWRGAVRG--YQERVAHMEMSLGQARERLGRAVQGAREGRLALQQLQAERGGLQ
ERRTVLEQRLEGRW--QERLRATEKFQLAVEALEQEKQGLQSQIAQILEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQAPGSGSKTALSFQ---------------------------
--------------------------------------------------DPKSELHFPG
TPECRRLAPLLPALSPTPLISPLPDTLGTPVPAFLKSQEFLQART--PTLASTPIPPTPQ
APYPTTDTEIRAQEAPLSLLQPQDR-GQQVPEPLQTEAKA-TIPASILPSPEEPGGKQQE
ASISQSLEDHVSLAPP--LS----PDHPSLEVEDGEPS-------------GSGVSSIPQ
EEGEGQIWRLTEEKS----VTEVTVVSSLQQKTWQEEVGLNKEEVQDSQGQGHLEKETLK
SLKEEIQEPLMSLEKQTHETLRSLEKENQEFLRSLEEDNLETL-KTLEKKNQDLLTSLEE
KDL-EVARPLEKETLEPLMSIGKEEPHTWQSLEKEDQEHMKSLEDNIETFLFPGRENQE-
LVRSL--EEENL---------------------ESLRALEKETQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RPQEAENQETLRPVPKE
NQE----------------------LLRSPKDENQE----------------------TL
RPLEKETQKSVISLND--------GNQETLRSLENR------------------------
--------------------------------------------------------EQAP
LRSQ--------E---------------------KE------------------------
-NQEIFEKETQESLR----------------------SLEEEDQKALRPLEEVNLEPLKS
LGKDQEIL-RPLEK-ENQELLSSLKEGSIETIQSLETENLEPMKSV-EEDLEILKSTETQ
EPLRSLEGKNQGTMKPMEKE-SQEPLGS-------VKENQETLRPLGKENQEPRRSLGEW
DVDNLRSPEEVNKESQRYLEEERNLEKG--ENQESLRSLGEEGQELPLSADQQRWEDVVM
GDQEL---GEETHPGRAGVGNE-EAEL-GLRGRDGFAGKEEAAEQGELWVNT-VGEAWST
GEGHPGSLEPEEQMV---PAEGAMRQGGPEG-----LQDPEGQPEQVGAPGLG--AAQGK
P-VVEPTLEDEDVAPGGERSSPR---VTLGSETAVGES---DPGSQ--------------
--EGWDREAVGLEDPGPL----AREV-MEPPLGEEGLETKRVEGLESAKKDLEEAEALES
ELSKLPRK---NGDPLEPKGSAAWEKSEPEAPPGAEEV--FPAGTL-------CPEG---
------SSAPPPRPLGSEKAEEDAPSGLGPPSPR----PTAPWEPTPLPEDAPGPQP--Q
AEGDQEA--SGGPEGRAEALGKLEG---EL-GSGGIPEG-LQDEG-----KESGEESEAD
ELGETLPDSTPLGLYPQSP-----ASPKQGLAGEERPSPQ--GQDGKEGWGPAA-PAAEG
----------LGTQPSEEEEG--------DEEEGQHPDSDLSE-EFED-LATEA------
------SLLPGVPRE--AAAPVGPAPPLL------LEPP-AWDQGGESDGFADEEESGDE
GEEDE----DDEEEGRGPGAGRWGAGPSVGSLQALGDPQGASPLQPD--PVGFRV-PWD-
DGLRGAVADAPVTVLE----------TESQDSAEPSGSEE--------------------
--------------------------------------------GSEPVPLEGE-DHGP-
-GPLEPPSVAEDMGR-GAGATLDVNGQGPSVEE--EESEPANRGVMNGLEQPEGVGQGKL
GAPEGDRGSPLEG--DEGTALKTPWE---------------QR--EGDGDSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLGAELGGLRAQ-TGDASWRARADDELAALRALV---DQRWRE
KHAAEVA---RDNLAEEVAGV--AGQCQ--------------------------------
------------------------------------------------------------
------AWRGAVRG--YQERVARMETSLGQARERLGRAVQGAREGRLELQQLQAERGGLR
ERRAALEQRLEGRW--QERLRATEKFQSAVEALEQEKLGLQGQIAQVLEGRQQLAQLKMS
LSLEVATYRTLLEAENSRLQTPGGVSKASLCFQ---------------------------
--------------------------------------------------DPKLELHFPG
TPEGRHLGPLLSALSPTSLSLPLPDTLETPVPGFLKSREFLQART--PTLASTPIPPTLP
APCAVIDAEIGAQDAPLSLLQPQIG-REQAPEAMQA----LAIPSSILPGPEEPGGEQQE
AGTGQSSEDHTSLAPS--LS----PDPCSLEAKGREPR-------------GSRMVSRFQ
DEGEGQIWGLAEKET----AIEVKMVNSLQQETRQEDGALNMKEIQDSQ--GPLEEETLK
SVEEEIQESLISLEKQSHETLRSLE-ANPESLRSLEEERLDAS-KDLEKENQELLTSLEE
KDV-EVLRPLEKETQGLLKPVGKEDPQTLQSVEKENGELMGSLEGNGETFLYPEKENHV-
LERCL--EENF----------------------ESMRDSEKETQEPLRSLEDENLENLRL
LEKENQESLNSPEDEKHKTLRPPEKENQEPVRCLEKDDQGTLRPLEKENQESLRS-----
-----------------LEE----------------------------------------
--------------------------EDQESVRPLEEEYQEPERSVGDENQETLGSLEKE
KQRSLGSLEEE-DQKIVIPVEENQEAVRSLE-EDQETLNPLEEEYQEPVKSVEDENQETL
GSLEKETQRSLRSLE---------EDRETVRPLENEHQEPMVSLVEEDQAIL--------
-----RLLE-----------------------KENHESMKSLEDENQETLGSLEKENQRS
LGSL--------E-------------------------------------------EEGQ
ETVSPLEKENQEPVECLEEEGQETLRSLEKENQDPVGCLVEEDQATLRSLEKVKPEPPMS
LGKDQEIF-RSLEN-ENQQLLWFLKEESSKARRSSESENLEPPKSA-GSDWGILKSLETQ
EPLWSPEEMSQKTTKPLDKE-IQEPLES-------VEDSQEMPRPLEKEARESLGRVGEW
NLENQGPPEELGQESQRSPTEEETPAQT--GDLEPPRSLKEAGRQSPARAHQQGREDTL-
GCGEQ---DQDSPPGRAAVGQEAEAKPIIVRESGGFAGKEEPEGCGQLWLAA-AGEAWSA
GEGHPGSPEPREQSA---PVEGASGEGGIEG-----FRDPEGPPEQVRAPGIQ--PAQEV
SEARELVLEGGQESPGGDQASPE---VTLGLGTAVGES---AAGSW--------------
--QGPEREVGGPEDPGCP---AREEG-TTPPTGKEGLEGERRQGSEGSREDPEEADALDP
ELSTLSRR---SMDPLEPSR--GWEEAELEAPWGAESG--LPAETE-------GPSPGGS
-----SRGAPWPGPLALEEAG-EAELVLGPTE---------PRAPTPVPGDAPGLQL--L
AEGSREA--GWGLDGRAEALAGLEGEQEGL-GSEGSAED-LRE-------GENREDSEAD
ELGETLPDPTPLGLYLQSQ-----ASPRWDPVGEPRPSPQ--GEARKEGWSPPV-PTSEG
----------CGAQRGGGEDQ--------DEEEECGQDSDLSE-EFED-LEAEA------
------SRLPGVPRE--AVEPLGRAP----------EPA-AWAGEGESDGFADEEESGEE
GEEDK-----EEEDGGQPGAGPWGPGSSVRPLPALNGPPRGTFPGFE--ATDGTV-AWV-
DGPRDAAAGVRRTALE----------TESQDSSEPSGSDG--------------------
--------------------------------------------ESGPVSLERE-DQVP-
-DPLGTLGGV--------GDSLGVPGQGPSLKE---ELERVSGGAVNGLQQSDRGEQGTL
GGPAGDPGSPLEEEDNEGGALKSPWAGPPLHLGVGQFLKFTPR--D-DVGSWSSGED---
---------------

------------------------------------------------------------
------------------------------------------MEGCLGEESFQMWELNRR
LEAYL-ARVKALEEQNELLSAELGGLRAQ-AGDASWRARADDELAALRALV---DQRWRE
KRAAEVA---RDNLEEEVEGV--ATRCQQLRLARERTAEETARSRRAVEAEKCAQAWLST
QAAELERELE----ALRAAHEEERAGLNAQAACAPRGP-APP---RGP-PVPAPEVE-EL
ALRLGEAWRGAVRG--YQERVAHMETSLGQARERLGHALQGAREGRLKLQQLQAERSGLQ
ERRAALEQRLEGRW--QERLRATEQFQLSVEALEQEKQGLQSQIAQVLEGRQQLAHLKMS
LSLEVATYRTLLEAENSRLQTPGSGSKASLSFL---------------------------
--------------------------------------------------DPKLELHFPG
TPEGRRLGPLLSVLSPTPLSSPLPDTLETPVPGFLKSQELLQGHA--PTSASTPIPPTPQ
APRPATDAKIRAQDAPLSLPQPQVG-MQQVPEAVWAEAKV-AIPASVLPGPEEPGGKEQE
PSPGQSSEDHASLAPA--LS----PDHPSLEAKDGEPS-------------GSRGSSRFQ
EEGEGQIWGLAEKET----AVEVKVISSLQQETWQEEGDLDMKEIQDSP--GPLEKETLK
SLEEEIQEPLISLEKQRHETMRSLEKENQESLRSLEEENLEIL-KTLEKENQELLQSLEG
KEM-EVMRPLEKETLELLKPIGKEDPQTLQSLEKESQEIMRSLQGNVGAFLSPGKENQE-
LVRSL--EEENF---------------------ESLRALEKERQEPL-------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------RCQEVENQETLRPLAKE
TLQ----------------------PLGSLEEKDQE----------------------TP
RPLGKEN-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------QPLR----------------------SLEKEDQMTLSPLEQVKPEELKS
LGKDQEIV-RLLEK-ENQDLLRSLNEESVEAVRSLGTETLEPLKPT--------------
------GEENLEMLKPLEKE-SQEPLGS-------VEGNQETLRPLEEETQKSLSSLGGQ
SVEDMRSPEEVDKGSQRYLXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX---XXXXX-XXXXXXXX-XXXX-XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXX---X--XX---XXXXXXXXXXXXX-----XXXXX----XXXXXXXX--XXXXX
XXXXXXXXXXXXXXXXX-XXXXX---XXXXXXXXXXXX---XXXXX--------------
----XXXXXXXXXXXXXX---XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX---XXXXXXXLP--GWEESEPEGPEEAEET--FPAETS-------CCDG---
------SDTPQPRPLSSEGAKEDAKAVLGPPSPR----P------TPIPEDAPGPQP--L
AEGSQEA--SWGLAGRAEVLGKVEGEQEEM-GSGGIPED-LSEEG-----EESREESEAD
ELGETLPDSTPLGLYLGSP-----ASPKWDLAGEQRPSPQ--EETGKEGWGPAV-LASEG
----------LGAHPSEEEE--------GGDEEERGHDSELSE-EFED-LGTEA------
------SLLPGVPGE--VAEPPGQVPPLL------LEPA-VWDPDGESDGFADEEESGEE
GEE------EDEEGERGRGAGRWGAGPSVGSLPALSGPQRGNLLGSE--TMDVSV-PWD-
DGLRGAASDAPMTALE----------TESQDSTEASGSED--------------------
--------------------------------------------ESDAIPLERE-GQVP-
-GPLGTLSAVEDTGL-EVGDTLGVNGQGPSLKE---ELEHVNGGVVNGLEQSEGVRQGKP
GPPEGDQGSPLEE-EEEGGALKTPWAGAPLHLGQGQLLKFSQR--EGDRDSWSSGED---
---------------

Query Results

"ENSGT00730000110953_1"

ENSGT00730000110953_1