ENSGT00730000110871_1 : Linker Region Query Results

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQVDFDRHPEQ-----REM----------------FTV---SDHPPE---
------------------------------------------------------------
-------------------Q-CGMFTVSDH-PPEQRG------MFTV-SDPHPEQR--GM
FTVSDHPPEQRGMFTVSDHPPEQRGMFTVSDP-HPEQRGMFTVSD----------HPPEQ
REMF--------T--------VS-D--------HPPEQCG-----MFT--ECK-QECELA
IADLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHLAAIEKLREDLQSEHCRCLEDLEFKFKESEKEKR----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--RGRKDHVDELN---------
----PERHKESLPCFQAELEESHRHLLEAPESPLCIQR---EGHISDSCCAE------TS
ALGHGW---H---LEPS--EGCSQELPWVHLQGVQDRALEANTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPT-------AQDGELA
ALHMKEDCALQLILARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KQDSLHQTILTQELEKLKQKHDEELQSERDGLRTAAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKAALHEKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
TDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNINIRKKMAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPAGSP-PEGPEVQLEVTQSALLQRESEVSTEWGH-----G
IISPSGAISAHCNLCLRSLSNSPT-----SASRVARTTG---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSHAGSLQSEL----LCSQA-GG--
---------------------RRGQALQDELEAALEAKEALSRLLADHERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRRVLEQ--------QPLAAG--
AEPPELQRLRVQCARLSRQLHVLHQRFLRCQVELDRRQACRTTAHTW----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMTLEDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEEV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPTDACDASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SMLGSSCHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLRDRVDTSLPQP-QGPGLLCSP
GVST---AALALQWAESPP-----------------------ADD-HCVQRTAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGARLSPGSGGPE----
---------APTAGPVT----PAAISGRFQPLPEAMKEK-GVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVQEDLLCGG-K----------
TQFCFDVPTVCPDWRGELLQVVQEAFE--KEPEIQGVELQPRLSG-SDLGGDSFPLERLE
KVVSEQGD----LQEKSLEQLRLPDRSSLLSEIQALRAQLRMVHLQNQEKLQHLRTALTS
AEARGSQQEHQLRKQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQESERLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELRKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDQVP-GSRLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAMDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
VAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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-----------MEAAESEQRRRKVEAGRAKLAHFRQRKAKGDCANSEKKTSK--------
------RKGSAVDAPVQEEG--PVATDDDDGTRVVGGG--VCKSTACI-------DSPDG
AGGAFA----AQER----------------------------------------------
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------------------------------------------------EQECE-QEREPE
IAELVGRPNE----QQ----------------------------Q---TQTVHSLELEAL
RLSLSNMHTVQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
TREKEE----MALRCSQKTAELKEKLQSEME-KNVQMIETLKQDWESERDL---------
---------------CLEKLRKELSAKHQLEMEDLRSQFQEEL--------AEQKAELEK
IFQAKNQAEST-LENLEAQYEATIKKLREDLQSERCRYLEDLELKFKEKEREKQ----LE
LETLQASYADLKAQSQEEIRRLWSQLD-----STRTNRQELN-ELQEQLLARASHVEELE
HLKRDFKQQ---------QQQEK--TQHESELEQLRIYFEEKLRDAEKTYQEDLTLLQHR
LQEVKEDSLLESVE-------ISSS----RTCLEETPEK--EKTGRLDQLDLQ-------
----PEQHEESLVCFQEALGGDHGRALEALTSPLHTQR---DRHVLDRRLSE------TE
ELEREH---LELEWLPVALSEHSPGLAPGRPPCAQDAALEDDAEVAARVLD-LETENKVK
LSLLQTE------LREEIELLKIENRNLH-EKLQHEIRLKEDLEKVKHNLVEAHQEELNK
TKEKNQQMKQEFKKKEAEWKALSEDLQREAEEKLTLMLRELREKAEAEKQSVVNKFELRE
KEMKQLQDQQAA------------------------------------------------
---QILELERSLTEQQGRLQQLEQGLAADEAA---LCGRCGQEPPAGAG---------EQ
ALRVQEDCALQLMLARNRFLEE----------------------RKEITEKFSAEQDAVL
REAQEKHAREL----Q----LLQDRHQQRLQAVSRELETRHQAELRELAASLESERRALL
DVRVAELQTKHAAEIRALETRHRSSLDSVESCCLAEIQTVRDEHRRAVARLQADFAEQLR
RKDAAHQTVLSQELEKVRLKQDKEPQSAQDGPGADASA--GHGTSLDARSPELLGV----
------------------------------------------------------H-----
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----------------------------QEHQGEFESEKKAALHAKQEACRPESEQAQAL
CRKEKESLS-LQLQEKDAQIRQLEEQVL-SLSQKVEESHSELEMLQQRRDRENQEGENLI
SMLKADADLSHSERRALQDALRRLLALFGETLKAAVALRSQIGERVGLCLDDAGTAGA--
-DQAL---------PAAPTLDESWS--DAAL------LEVDRTVSECA------------
---EMSSAAEVSSHVRESFLMSPDSALGCEQTVRRVYQSLGLAVDGLLEMVLDSTRQLEE
ARQIHSRFEKEFSCKNEETAQVVRKHQELLACWEEQSAAKAGLELELHTAEGILEGLKVE
KADLQEALGRKEESERDLVLELEGLRQQLGQAA------REQASLKEEYALLWSQKEASA
VQAEEREAGTPAT-AAHEDPALLKEVECLTREQLETRKQSEKDRAALLSQMKVLECELEE
QLSQHQGCARQAEE-ITALKQQMASLDKHLRNQRHFMDEQAAEREHEREEFQQEIRRLEA
QLCQA--ARPQPQGLLDSPQ-----HAGLDEEVELLQQKLREKSDGFNELVIKKELADRQ
VLIQEEEI-------KRLEEMNANTRREVVRLQEELEKQKKIVIEL-QDKEALKEQQMTH
LPLESTPQ-SEAGEGRCPWPAPDSP-PAGAEAQREAAQGAPLQHDGEVLDLKGHLEEIKD
DLANKNE-ALYLNLKSDV-QNTQTAVSIRDLEEENANLK---------------------
------------------------------------VVCARSSEVEELKATIENLQENQE
RLQQDKAEEVERLHEVIAKLQQELSLMVPAVQGAGESRVGSLQSEL----LCSQADGP--
----------------------CGQVLQGELQAALLAKEALSQLLADQARGHCQALEALQ
QRLRGAEEAAARQLAEL-----------------GRSEALREAQVEGMASRIREFEAALK
AKEAAIAERDSEIDAVNKWKAAHSTALKAVLAA-VARFRRALEQ--------QPLAGP--
AEPPELQRLRAQCVRLSRQLQVLNQPFLRCQLEPDRQQVHGAAARTR----------PPG
ACRHPGPEGGSEVCRDAEMPEQ-GVSSRWSTPGL----HGRDQDLQ-------GDLPPAR
VSVTLKDTGLHT------QESAEPV-LTVGQRQLQPEP--FSVKN-----ELHSSLEGSG
VAWGRA----------------------QGKEKV-LEDCQLQKVDLIAQVKELQEKLNHL
IYSATFQDVSTADFKFQQPFAS-AFGLENSSS--GGS-----------------------
-HNGEETDTSPPVDAFDADKTM---------------------RDLT-------------
--D-------AVKDENYLIRN-EMPNFPIQETLELQDRPHSSPA----------------
-----------------------------RVLGGARAPRRSDLAEPLKSPVRVLDLSSWS
SPEVLRKDS-ALEPQPS---LLLTPRSDVLSLRSADASLQDGTQASLLLA-SEPGLLCHP
GVSA---AGQAPPWAGSPL-----------------------ADH-PPVERTPVEKDVED
FIITSVDSQETLRSP---------PLRLEGNND-GSEESDGSGFGGKLSPRSGGPE----
---------APAHGPVS----R---RSRSQQLPGAMKGK-DAHAQHVKALLQMVREESRQ
ILALSESCGPLSALSRGE------------PRAPLDPIPREGQGLLEAAP----------
KKGEKELSELCLDWRGEFLQVVQEAFD--KEWKTLKLQLQPGLGS-ADPGGRDCLFERLE
KVVQAQGD----LQEKSLEHLRASDRSSLLSEIQALRAQLRLTHLQNQEKLQQLCAALTS
VEARGSWQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLSEEQ
EKANGVRKLLAVEQSAVKALKSELCECKQENERLLKSLDAVQQEVLQLR-----------
-----------------SMLDGKESDLQA-------------ALRELESE----------
--RGKEHALQSRLEEQQL---------------------RHLQREGQSSKSLE-ELRASL
EKQRAQS--SRLCVALKHEQTA-RDNLQKELRIEH----------SRFEALLAQERGQ--
-LAQLQKDLDAEK-SRSLEL------SEALQHERLLTEQLSRRTQEACAH--QDT-----
-PAPQALLRKLQEEKARVLELQAVLGEAQQQAAHAQQQLEAEAQ-TRCEEVRREK-----
------------------------------------------------------------
--------------ERELELQRQREEHKIRQLQRT---VRELESEEEALRSGGHRGTPRG
----A--------QGAD---GPDQLREQQQELEKIRQQLLCAAGLLTSFVRQTVGRTISD
WTSSNEKAVASLLRTLEELKPELSRSTSL----KKKKAAELQV-QLVDVLLK-DNDSLTK
ALNTAAEEKSELSRAVSRLE---KT--LRHHVQKG--------------CVLSR-SDRPA
GKQDRMVLQSSQ-HLDLGRPPT---------AVGADAN-TCNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKRI--TTSRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAP-GKALR--QGPRA----P-LRLRSP---------
-----------PESRESIPTRDVPSGHTRDPAR-----------------------GPRP
ATAASPSRRGRSTPSPHSRLERSLTASEDPEHSLTEYIHHLETIQQRLGGSPPD--FTS-
KKSCHQKSKQ--------

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-----------MEEDEQEQRRRKVEAGRAKLAHFRQRKTKGDCAHSKKKTAK--------
------RKGLAVHASVQEESPSPVVTQ-EGGLLE-GGD--ICRGTACSS------SSPDW
PGGAFA----TQE-----------------------------------------------
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---------------------------------------------------------QDQ
DCEPGNTPEDKAGWQQ----------------------------Q---PQATHSLELEAL
RLSLSNMHTVQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELVQEQH
TREKEA----MAHCYGQEIAELKEKLRSEVE-KNAQMIETLKQDWESEREL---------
---------------CLENLRKELSARHQSEMENLQNQFQKEL--------AEQRAELEK
VFQGKTQAEVS-LKSLEAEHQAAVRKVREDLQLEHCQYLENLELKFREKEKEKQ----LE
LENLQASYEDLKAQSQEEIKHLWSQLE-----FARTKRDELH-E---PPLAGVLHLEELE
QLWQEFAQQ---------QQRDR--AQHESVPEQLRVYFENKLRDAEK--QEDLSLFQQR
LQEAKEDTDLGSVV-------MSSS----CTFLEDTSD--REGKERPDQLDFQ-------
----LKQK----------------------------------------------------
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--------------------------------------------ELKFSLVEDHQEEVNK
AEEKIQLLKQEFKKKEAEWESSHEDLKREDEEKVTSMLLELQEKAELEKQSIISRFELRE
AEMKNLQDQQAA------------------------------------------------
---QILDLEKSLMEQQRCLRQLEQGLSGDDAP---LCSRCGQDTSSAQ-PG-----EHIT
CL-QKEDCSLQLMLAQNRFLEE----------------------RKKIVEKFATEQDAFL
RDTQEKHTREL----Q----LLQQRHQQRLLSLRTELESKHQTELAELMATLESEWQVLL
ETRVAELQVKHAAEISALEKRHLSNLDALESCYLSEMQIVRDEHRQALELLQADLEEQLR
LRDSSHQVTLTQELEKLKQKHNVELQSTKDSLRTEMST--IHAEQLKVLDR---ELQGAH
QDKFESEQKA---V---VGGQEVWSLECEP---------------VRQL-SQEQD-----
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---------PLQL-QAESQTQQLKDQVL-SLRQEVEECRAELERLQQRRERENQEGATLI
SMLRADVDLSQGERRALHDALRRLLGLFGETLKAAIALKSRIGERVGLLLDHADTTAV--
-DQAP---------S--TALEEVWSDDAAL-------LELDRILPEGA------------
---EMSSVEDISSHVCESFFMSPESTLECEQPIKRVYQSLSVAVDGLLEMALDSSRQLEE
ARQLHSRFEKEFSHKNEETAQVVQKHQELLECLRAEGTAKATLALELHTAEGLLEGLKVE
KAGLQDALARKEASEQQLVLELESLGRQLQQAA------EEQAVLREEHSLLRSQKEAQA
VEAEARVAGTCVT-AAHRDSALQKEVETLTTEHSESRRQAEKDCAALLSQMRVLESELEE
QLLQHQGCAQQIEE-ATILKQQLAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQKLEG
QLRQA--AKLRPPSPHDS--QQCL---QLDEEVELLQEKLREKSDECNELAVKKELADRQ
VLIQEEEI-------KHLEAINAHTRGQVALLQEELEKQKNIVKEL-QVKEALTEPQTSD
LLHVPTSH-SGPNGSRCPVLLLGS----PPEAQPEIIQMARLQDG---------------
------------------------------------------------------------
----------------------------------NEVEYHRSSEVEELKSIIENLQENQE
RLQKDKAEEIEQLHEIIEKLQGELVLLGPVVHELSDHQADSLHS----ELLCFQADGPCG
Q-------------------TLQGQALQGELEAALSAKETLVQLLADQSQGHSKALEALQ
QRLQAAEEAAARQLAEL-----------------GHSVALREAEVEDMTARIQEFEAILK
AKEAIIMQRDLEIDAMNKQKEAHFVELEAILLA-LARFRHTLEQ--------QPP-----
-EPPELQRLRAQCIHLARQLQVLNQWFLRCQVELDKQQARGVLK----------------
THPHPHVDTESGDLLEQGGGS----------RWLA--STPHGWGLQ-------DDLQPAK
VLGTLKDADLHK------PENVVSV-LTFCQRQLEAEL--LLVKN-----EIRLSMEDDT
RAPRRMKFKKGSVLPWRRRVHLCNFRLCRGQGKW-IEDCWLRKVDLIAQVQQLQEKLNCL
SHSMAFQDADLVGSRFQ-PSTL-TYLSENSSS--SSS-----------------------
-CGKAAADLLLPVDTLNNDKTT---------------------WDLT-------------
--D-------VIKNQDSSIID-EMPNSPTQEKIKPKDVSLSLQT----------------
-----------------------------SVHSD---SLRVEEAKPPKDPETVQDLSSWS
SPEVLRKDS-SLEPCTRI---PLTPCSGAMSLCSAEGSPQHTI-SWLLQS-SL-------
GRS---IGEQTPLWT---------------------ATPSS---DHQPVERMAAEKDVED
FT-TSFESRDMLRSP---------PPGLEEKND-ESAKSDGPCCGAMLNLRSGQPA----
---------APTAGPVTAAP----VSRGFLQPPGQMQEK-EVHTKHVKALLQMVCDESHQ
ILALSESRDLPSTLSKGE------------PYAHLAYFLGKGQGLLEVTP----------
KKGEKKPLDLNLDWKEEFPQATQGIFE--REQKMVQAELQPGPCG-SDPGDHSSPCKKLE
KVVQEQ--------EKTCEHLCLPDRSTLLSEIQALRAQLRMTHLQNQEKLQQLCEALTS
TEARSSRREHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLSEEQ
ERARGVRQLLAAEQSTVQDLQSELRECQHENTRLLESLGEAQREVLQLR-----------
-----------------SLLDGKESDLKA-------------ALEELEHE----------
--RGKERILQAQQEEEQL---------------------RHLQKEGQSSKALE-ELKVSL
EKQFAQN--SQLNVALNHERTV-RDNLQQELQIEQ----------SRCEALLAQERGQ--
-LAELQRSLEAEK-KRALEL------SEALQHERLVTEQLSRGAQQPQP-----------
---HHVMLRKLKAEKARVLELQATLQVAQQQALQAQQQLEAQVQ-ERCAALGKE------
------------------------------------------------------------
-------------KERELELQRQRDEHKIEQLQQT---VQELQSKV--EMP-GSGPRLDS
----------------L---ELGSVWEQQQGLEKIRQKLLCVAGLLTSLVSHTMDRTLND
GTLSGEKAVSSLVQTLQGLKSELSMSTSHQK--K--IAAELQV-QLVDVLLR-DNDSLTE
AISTVTKEKAELCRAVSRLE---KT--LRHHVQKGC--------------ILSR-SGRSA
WRQDGTVSQSLPRNSDSGQSTL---------TAREKEN-TYSIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--STSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDQRGTPLLQGKAPH--PG-----PRVPWKQPSP---------
-----------LGARESPPTRDGPSHHTRDST----------------------------
--HHLPSERERCTPSSSSRLERSLTASQDPERSLTEYIHHLEMIQQRLGGAPPD--SNS-
KKSCRQKIKQ--------

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-----------MEGDEQERRRRKVEAGRAKLAHFRQRKTKGDCANSEKKTAK--------
------RKGSAIPAPVQEES--PVAPAEDGVPLG-GGS--VSAGTACT-------DSPDG
VRGVFA----AQSHDGSGL----------------------------PYWEKKKKTGQMS
QQIIPRKKFLL-------------------------------------------------
----------GLGLNSPPSV-YGVGALLIE-PQAPPG------LFTLKNTPFPRHN---F
KSISLLGDSCMGVATVGPGQMSVRSSLGVG----------------------------FS
SGVP--------G--------MS-G--------PWGVERCGVGQTTMMAAEHE-QEHEFE
IIDLMGRPNEQQQ---------------------------------MQLQPAHSLELEAL
RLSLSNMHTVQLELAQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELGLIREEH
AREKEE----MALRCSQETAELKEKLQSEME-KNVQIIETLKQDWESERDL---------
---------------CLEKLHKELSAKHQLEMEDLRKQFQKEL--------GEQRAELEK
SFQAQNQTESAALQNSVGQKGAAVREPCEDLPCDRCCYLEGIQGKLREKEKEKQ----LE
LETLQASYEDLKAQSQEEIRHLWAQLD-----SARANRQELN-EFQEQLQARASRIGELE
LLKQDLEQQ---------QQQER--AQHESDLEQLRVYFEEKLRDAEKSYREDLILLQQR
LQDMKEDSFLEAVE-------ISAS----CTCSEETPE--REKIGCHDQLVLQ-------
----PEQHKESLACPPVELGENHRHELEALQSWLCKITLQTLRHVSGDRQCV------QS
WGGWPW---S---LT---VPPHPVALAVLRLPGAQDAAEEADWEVATRDLG-LETEHKVE
LSLLQTE------LKEEIKLLNIEKRNLY-EKLQHEIRAKEDLEQVKHNLLQAHQEELNE
AKEKSQLMKQEFKQKEAEWRVRSEGLKRDAEEKLALLLLDLREQAAWEQRSLRSCFELRE
AE----------------------------------------------------------
------------------------RLAVDEAP---LCGQCGREPPR-------AR-----
---AQEDCALQLMLARSRFLEE----------------------RKEITEKFKVEQDAFL
REAQEQHAHEL----Q----LLQERHQQQLQSVTQELEARHQAELRELAASMESEQQALL
DARVAELQIKHASEVSALERRHLSNLDSLASRYLSEIETARKEHRWAIVRLRTDFKEQLQ
KKDAFHQMILTQELEKLRLEHDKELQSVKGSLRGGVSA--GHGSSLQALE--LPGV----
------------------------------------------------------H-----
------------------------------------------------------------
----------------------------QAPQGEFDSEKKAALHAEQETYRLESERAQPL
CPEETESLS-LQLQEKNNQIQQLKEQVL-SLSHKVEECHSELETLRQRRERENQEGENLI
SMLKTDADLSHSERRAVQDALKRVLVLFGETLETAIALKSQIGERVGLCLDGAGTTGP--
-GQAL---------WAALAVEETWS--DAVL------PDVDGTLS---------------
----------------------------------GIYQSLSLAVDGLLDMVLDSTRQLEE
ARQIHSCFEKEFRCKSEEAAQVLRKHGELLQLLEEAGVAKAGLQLQLHQAQGILEGLKVE
KVDLQAALDRKEESEQGLVLQLESLREEHALLQGQKEEREAGSFLRDEAQPLWCGAPS--
MSAFFISL------------ALQKEVECLSKEQSETRRQAEKDHAALRAQVQLLESELEE
QLSQHQGCAQQAEE-VAALKQQMASLDKHLRSQRHFMDEQAAEREHEREEFQQEIQRLEE
ELRQA--ARPQPQGPQDSL------NMPFIAEVELLQEKLREKSDGFNELVIKKELADRQ
VLIQEEEI-------KRLEEMNADWRREVVQLQEELETQREIVKELQKHKDTLEEQQTTH
LLPVSTLQ-SELDRGKCPGSSRDSP-PQSPEEQLEATQTSFLQQEGKVITSNAKFQLFLS
LLFSDDNDMQKLNALLGKSNHSHLNISKINTYKNVFYLQ---------------------
------------------------------------GVCARNSEIEELKAIIENLQENQK
QLRKDKAEEIERLHEVIGKLQQELSLMAPRGPEVSDVGLGSLQCEL----LCSQVVGG--
---------------------PCRQALRGELEAALAAKEALSQLLAEQARGHSQALEALQ
QQLRAVEKAAKGQLAEL-----------------GHSTALREVEIESMASQIQEFEAVLK
AKEATIAQRDLEIEAMHRGKAAHAAQLKSVLSA-LARFCHALEQ--------QPLAWP--
AEPPELHRLRVQCVHLSHQLQVLNQQFLRCRMELDRPPLPETQLYPG----------PEG
SNE---PGGASDAEVPEQGVN-------IRQLALG--PHDQDLDPQ-------GGLQPVG
ILVRSEEEALCG------HSSLASL-LTICQRQLRSEL--LLVTS-----EICSSLRNGQ
----------------------------QDKEKI-LKDCQQWKVDLIAQMKQLQEKLNQL
IYSMTFQNVDSADCEFQQPLASSAFRFENSSS--DGS-----------------------
-HNGEETDKLPPIDIFNTNKTM-----------------------DI-------------
--T-------DIKNQDSLIRN-EMPDFPIQEKLELQDGSPLSA-----------------
---------------------------------SVHSSSHRDTAEPLKSQVRVLDLSSWS
SPEVLRKDS-ALEPQPS---LPQTPGSDILSLRIADTPLQDR--TSLLQM-DEPGMLCYP
DMSA---AGQDPPWAASPP-----------------------PEH-HSVARTAVEKDVED
FIITSFDCQETLPSP---------SLRLEGKND-GNDESEGSSFRGKLSPQSGTPK----
---------APADGPV---------SRRSLQPPGAMKGK-DIPALQVKALLQMVREESRQ
ILALSEGHSLPSALSGGE------------PRTALGAPWEGQGLLEAA-P----------
HKGDKGASDVCLDWRGECLQIIREVFD--EARETLMRQLQPGLSG-LDTGSRDYLFERLE
KVVREQGD----PQEKSLEHLRLSDRSSLLGEIQALRAQLRLTHLQNQEKLQQLCAALTS
VEARGSWQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLREEQ
EKANSVRKLLVAEQSSSRDLKAELSECRQESERLLQSLDSVQQEVLQLR-----------
-----------------SMLDSKESDLQA-------------ALQELEHE----------
--RGQERALQSRLEEEQQ---------------------RHLQQEGQSSQSLE-EVRASL
EEQRAQS--SRLRVALKHEQTA-KDNLQKELRIEH----------SRFEALLAQERGR--
-LCELQKDLEAEK-SHALEL------SEALQHERRLTEQLSRRAQED-------S-----
-PAQRALLRRLQEEETHVGELQALLGTL-------QQQLEAEAQ-RRCEELWREKEVSAT
STTAMEALQPQKRELRFCLEREREKPARLQADLEQVHTRWREQGGPEDARSGVETRQSQA
EAGEWSRWHRDKEKLRELELQRQREEHKIQQLQRT---VRELESKEEALRSGGPHQDAPR
----R-------VDNPS---EPDQLREQQQELETIRQQLLCATGLLTSFVRQTVGRTIND
WTSSNEKAVASLLRTLEELRPELSRSTSS----QKKMAAELQI-QLMDVLLK-DNDSLTK
ALSTVTREKSELSRAVSRLE---KI--LKHHVQKG--------------CVLSR-SDRSA
WKQDGMVLQSSPQHSDPRRPPP---------AASMEAN-SCNVKMEKLYLRYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKPDKKI--TSSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRRGALAQ-GKTPR--PDNSGGGPRVLRQQRAP---------
-----------PESRESPPTRDISSGHARDPVL-----------------------GHGP
ATAASP----RSTQSPNSRLERSLTASEDPEHSLTEYIHHLEMIQQRLGGSSPDLDSTS-
KKSCHRKIKQ--------

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------------MEDEQEQRRRKVEAGRAKLANFRQRKTKGDCPNSKKKTAK--------
------RKGSAVHASVQEEG--SVATP-NSELPQ-GGA--VFESPSCS-------NTLEG
IRGASA----AQEQED-----------------CELDVT---------------------
------------------------------------------------------------
-----------------------------------------------------DL-----
------------------------------------------------------------
-------------------------GQQQ----T--QT-QPPQ-----------------
--------------------------------------------------TAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQH
AREKEE----MALHSGQEAAELKEKLRSEME-KNAQMIETLKQDWESEREL---------
---------------CLENLRQELSLKHQSEMDGLQSQFQKEL--------SEQKVELEK
IFQAKYEAEVS-LKNLEAQHQAAITKLQEDLQSEHCQYLQDLEQKFREKEKAKE----LE
LETLQASYEDLKAQSQEEIRLLWSQLE-----SMKTNREELN-GSWDPVLAQASHLEELE
QLRSGFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR
LQEARED-SLESTE-------ISSS----CVLPEETSG--REGKEPPDPLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLGQPKVQDSLVEDCQMKLSK
AEEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRE
SSMRHLQDQQAA------------------------------------------------
---QILDLERSLMEQQGHLRQLEQELTRDD-L---PCSQCGQEPAM------AQEEKDGV
PLREKEDCALQLLMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDAQEKHSHEL----Q----LLQQGHQQQLLALRMELETKHRSELTEQLASLESRQQALL
ETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHKQALELLRAELEEQLQ
KKESCHREMLTQELEKLKLQHAEELQSVRDSLRMEMSA--QDIENGKGPAA---DLQGAH
QQDPAMALHN---EGHLLAEDGDAVLGS---------------VDAEGLL----H-----
------------------------------------------------------------
----------------------------QAGPQELG-----------DAHTAEMQKSQ--
----AELAKPQELQASQDQVAQVRDKVF-LLNRELEECRAELEQLQQRRERENQEGTTLI
CMLRADLELAQGEGKALRDALRRLLDLFGETLKAAVTLKSRISERAGLLLDHEDAADT--
-SDAR---------LAAAALGDMWSD--EGL------LEVDRTLPEGA------------
---ETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTAVEGLLEMALDSSKQLEE
ARQLHHCVEREFRHRKEEMAQAVQKQQELLECLREESAAKDGLALELHTAKGLLEGFKVE
KVDLQEALGKKEESEQQLILELEDLRKQLQQAA------RELLTLKEEKSVLWNQKETLT
NEAKERE------------AALQEEVESLTRAQWESRKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLAEE-VATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEG
QLRQA--ARPRPPGPRDSQ------CVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEEEI-------KRLEETNASIQRQMVQLQEELEKQKKSMEEL-KEKEKLKQEHTGN
LPLTTVSR-SGLDEAGRPMLPQGSS-SRVLEAQPDVTERAVLQHEK--------------
------------------------------------------------------------
-----------------------------------EVVNRRNSEIDELKSLIENLQENQR
QLQKDKAEEIEQLHEVIEKLQSELSLMGPKVHEVSDPQAGSLH----SELACLRAEGLG-
-----------------------GQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQ
QRLQDAEEVAARHLAEL-----------------EHCVALREAEVEAMASQIQEFAATLK
AKEAIIEQRDLEIDAVNKWKVNHSLELEAIILA-LAHFRHALEQ--------QTCATP--
DEPPELRQLRVQCARLSHQLQVLYRPFLKCRMELYQRQSHVASIGC--------------
----ANP------CA------D--------------------------------------
--------DELE------QEGVSNR-LAL---------------------------APHS
L---AA----------------------QAK-EE-LEDCPLGKANLMAQVRQLQEELDHH
VHSVASRDTISETCKLQQ-----PNLSENGPR--NHC-----------------------
-CNGEESKPSPPDDVLNIAKTT---------------------WDVI-------------
--D-------IIKNQDLLVQI-EMPDFPTQEKLTSQGGPFSSQA----------------
-----------------------------GGHSSS--LLPEEAAEPQQDPVRALDLSSWS
SPEVVRKDP-SLEPQHS---LPLTPGVGTVSLHSVDI-SPDWTDP-LLQA-DVSGLLCYP
GKSA---SGQAPLWAVA------------------------PSAGKHHAERTATEKDVED
FIVTSFDSQESLTSP---------SHELARRSD-GSRKSDGPDIAMMLTLGSEGSE----
---------TPTTDLVAA-AAAVPFSRRFVQSPGAMKEK-EIHAKQMKALLQMVFDESHQ
ILALSESQDPSSTLSKGE------------PRDPLDGFPRDSQTLSEVTT----------
DKGEKESLETHLTWSEELLRAIQEVFA--REQE--NAELQPRPYG-SNLGDYNSLVQRLE
KVIQEQGD----PQ-KVQDHLCLSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIANELQKTLSKEQ
ETASDVRKRLVVEQSAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRYGHVTW-----
-----SYCGTSSASAGRAMLDGKEKELKV-------------VLEELESE----------
--RGKGQALQAQQEEQQL---------------------RYLQREGQSSRALE-ELKLSL
EKQLAQN--NQLCVALKHERAA-KDNLQKELQIEA----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SHSLEL------SEALQHERLLTEQLSRNAQEACAR--QET-----
-QAQHALLRKLKAEKTRALELEAMLEKVQRQAA---------------------------
---------------------------------------------HTQQQLEAQAQ----
----ERCVELRREKERELEIQRQRDEHKIEQLQRL---VRELRWKEEAPGGNGPCWGSPG
----RG---------SL---ERDQFQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSMPTSF----QKKMTAELQV-QLMNELLS-DNDALTK
AVGMATREKAELCRTVSRLE---KT--LKHHTQKG--------------CVLNR-QSKSS
LKQDGADLQSSLRHPDPEWHSQ---------TTSGDTN-TCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TMSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALVH-PKSTR--HGH-----RTSQRQRSP---------
-----------SGPRASLPTRDTSSGPTKDSRH-----------------------SPRS
AAAVSLGK-ERSTSTPSSRLERSLTASQDPEHSLTEYIHHLEMIQQRLGGLPPD--S-T-
QKSCHQKNKQ--------

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----------MLKQAESQLAKAKAEIENKPVAEISNPK------LQRLYRKYIRAESFRK
ALV-YQKKYLLLLLGGFQDCEQATLSLIARMGIYPS-ADLQLSGSRSRPFTKFRCAVRAI
IAISRL--KFLVKKWNKVGRKSTQ-GESISHS----------------------------
--------------I---------------------------------------------
------------------------------------------------------------
------------------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSYD-------DTPDG
AGGAFA----AQLEDRDGEKREDLEQLQL----------------KQV---SDHPPEQR-
------------------------------------------------------------
----------------------GIFTVSDP-HQEQRG------MFTV-SDRHPEQR--GM
FTVSDHPPEQRGMFTVSDPHPEQRGMFTVSDH-PPEQRGIFTVSD----------PRQEQ
RGMF--------T--------VS-D--------HPPEQPG-----FFT--ECK-QECELA
IADLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIEKVPRTDSKTHASV---------
---------------YVV--------------------FPFSP--------APTRTLLV-
LIQT--EASRA-L-------------RRKNWRHRHCHQ-EHVDLPFPG------------
---------------GLSVTGGWRREKLKGPQAQLVPAGSGS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KERKDHVDELN---------
----PERHKESLPCFQAELEESHRHLLEAPESPLCIQR---EGHVSDRRCAE------TS
ASGQGW---R---LEPS--EGRSQGLPWVHLQGVQDRALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPT-------AQDGELA
ALHVKEDCALQLILARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTEHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLRTAAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKAALHEKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQTRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPAQEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPVRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
TDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNINIRKKMAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSALLQRESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLDL-KNSQTAVRLGELQEESVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRCVLEQ--------QPLAAG--
AEPPELQRLRTQCARLSRQLHVLHQRFLRCQVELDRRQACRTTAHTR----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMTLEDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLENVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPTDACDASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SILGGSCHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLRDRAETSLPQP-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRTAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGARLSLGSGGPE----
---------APAAGPVT----PAAIPGRSQPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVQEDLLYGG-K----------
TQFCFDVPTVCPDWRGELLQVVQEAFE--KEPEIQGVELQPRLSG-SDLGGHSFPLERLE
KVISEQGD----LQEKSLEQLCLPDRSSLLSEIQALRAQLRMVHLQNQEKLQHLRTALTS
AEARGSQQEHQLRKQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQESERLSRSLCEVQQEVLQLR-----------
-----------------CTLSRLIRCLP--------------------------------
--------------------------------------------------------SCVF
AGQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKASRRSTEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAMDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
VAILRL--RFLVKKWQEVDRKGALAQ-GKVPR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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-----------------------------------------------------MEEDE--
----------------QEQRRRKVEAGRAKLAHFRQRKTKGDCAHSKKKTAK--------
------RKGSAVHAPVQEES--PVAAE-DSGLFG-VRD--VYN--TCC-------ETPDG
ATGAFA----AEDRIYLPV---DQNQLEIKNAQARIT-----------------------
------------------------------------------------------------
---------------------------E-L--E-A-K-------L-L-S-R--Q-E---T
I--D-R---L-G------------------L-E-V-K-D-L-Q-D------------Q-L
-A-Q-R----------------S-G-S-----VP-------------CQQAHD-QEHELE
TAEHSSRQNDEGGRQQ----------------------------R---TQTVPSLELEAL
RLSLSNMHTAQLELTQANLQREKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----MALRSACEAAELKEQLQSEVE-KNVQMMETLKQDWESER-----------
-------------ALCLENLRKELSAKHQSEMEELQNQFQKEL--------AEQKAELEK
IFEAKDQAEFT-LRNLEAQHQEAVEKLRADLQSEHCQYLEDLELKFKEKEKEKQ----LE
LEALQASYEDLKAQSQEEIRRLCSELD-----CMRADRQELTAEFPEQLLVHAAHVEELE
HLKQGFAQE---------QQRQK--TEYESEMEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQEVKEDFPLESVE-------ISSS----CVFFEEMSE--DERKDHLDQLYLQ-------
----PGHDMDNLTRLHVRLEESCRRESATLSSPLHLQR---EEDTEE-------------
LEQEEQ-CHELELLRAAPAKEDSQGHARVCLQTMHDVALQVDMDVATRVLG-LETENKVK
LSLLQTE------LKEEIELLKIENRNLH-EKLQHEVRLKEDLEKVKHNLVADHEEELNK
AKEKIQLMKQDFRKKEAEWKVTSEGLEREAEEKLTMVLLELKEKAESEKRLMIKTFELRE
AEMRRLQDQQAA------------------------------------------------
---QILALERSVVEQQDRLRQLECGLLPGDEAV--PCSQCGRELP-------AAQDREST
VPRLKEDCALQLMLAQNRFLEE----------------------RREMTEKFTAEQAAFL
REAQEKHAHEL----Q----CLRDRHQQQLLSLRMELETRHRAELGELTASLESEQWARL
EARVAELQGKHAADISALETRHLSNLDSLEACYLSEVQAIRAEHRRALELLQADLEEQLR
EKDSSHQTLLTQELEKLRLNHDAELQSAKDSLRAEMSA--GHAESLRALAA---RLQGAH
QEELAAALRD---QRHLLEEERVAALDRVG---------------AEVLLLERQHQAALQ
ELGDAHMAKIQQQEPAKQAESQATQAPL--------------------------------
---------------------------EQVVQGEFGSEKKAALQEPAEAGSCGSEQAQLP
CPKEAAASLRLQLQEKSCQMQQLENQVL-SLNQEVEGYRSELERLQQRHARETQEGTNLI
SMLRADIDLSHSERRALQDVLRKLLGLFGETVKAAIALRSRISERVGLCLDDAGTAEG--
-DGL----------SAASALEETWPDAA-----L---LDLDRALPECAE-----------
----MSSVAEISSHVCESFFLSPESTLECEQPVRRVYQSLSMAVDGLLEMTLDSTRQLEE
ARQIHSRFEKEFSHKNEEMAQVIKKHKELLDCLKEEGAAKTALTLELHKAEGLLEGCKVE
KADLQEALGLKEESEQRLALELDGLRRQLQQEA------QAHMVLKEEYSVLQGLKEAAA
ATAEEREAGAPVT-VAHMDSALRKEVEYLTREQLETRKQAEKDREALLAQMGTLELELEE
QLAQHRGCARQAEE-VAALKQEMAALDKHLRSQRQFMDEQAAEREHEREEFQQEIDRLEL
QLRQA--AKPQPPGPRDS------WRAQLDEEIESLLEKLREKSDGFNELAIKKESADRQ
VLIQGEEI-------KRLEEANASSRRKVLQLQEELERQKKTVKELEQDKEALKEQQTST
CLFVCALH-SEPDAGSRPVPPLCCP-SEQAGLQLEAAQRALLQRESEVLELKEQLEKIKD
DLMSKNEEILHLNLKLDV-QNNRTAASLRERQEENDSLQVILHEEERDGTRG--------
-----------------ASEPPPVQQCGVESEAPSKVVYDRSSEIEELKAIIENLQENQE
RLQKDKAEEIEQLHEVIEKLQSELSLMGPVVHEVSDSQADSLQH----ELLCCQ------
--------------------VEGPAVLQGELEAAHAAKQALSQLLADQERGHSQALEAVQ
QRLRGAEEAAARQLVEL-----------------GRSVALREAEVQSMASRIQEFEAVLK
AKEATIAERNLEIAAMNKWKAFHCTELQAILLA-VARFRHAL-------EQQP-LAAL--
DEPLELQRLRAQCVRLSRQLQALNQRFLRCQRELDKQQAHGAAAWTQ----------VPG
GHPNPCVDTETAYDD----------------DFEQ--LTSVSRGPD-------HDPQHGK
VLVTLKDA---G-LQRQDS--VMSVL-EVCQRQLES--ELLLVKN-----EMCLCVDDSS
KVLGRR----------------------KGKERR-LDGCQLWKVDLVAQVKQLQEKLNRL
VYSLAFQNIDNEAFKLQQASAV-ACACVQEGSLDDGSHSP--------------------
-VGTA------PGDAFDFDKTT---------------------WDLV-------------
--D-------GIKNRDSWIGK-EMPNVPIQEKLGTQDGSLS-------------------
--------------------------LQTRVHSDSCALSHAEEAKPLTETARMLDLSSWS
SPEVLRKDS-TLEPQPSL---PLTPCSGALSLCSAGVSPPERMGASLLQS-HTPGLLSS-
PG---DLAGQPLCWA------------------------ESPSADHNPVERMAAEKDIED
FIITSFDSQNPLRSP---------PLGLEGKSN-GSETGDSSGCGAMLS---AVPGES--
--------EAPTTG-----PEDPAPFPEGLQQPLATMKK-EVHPKQVKALLQMVCDESHQ
ILALSESRDPPSALSRGE------------PHSPLHHLSSEGRGLLEVAP----------
DTGEKESPDPCFDWRGTFLQAVREA---------LAVELQPRLCG-TDPGDPSSLLQRLE
KVIREQGD----LQEKSLEHLRLADRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEARGSRQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLSEEQ
EKTNDVRKLLVTEQNAVKDLKSELCECKQENERLLQSLDDVQKEVIQLR-----------
-----------------SVLDSKENDLQA-------------VLQQLERE----------
--RTRERALQSQLEEEQL---------------------QHLQREAQSSKSLE-ELRLSL
EKQSAQH--SRLCVALKHEQTA-KDNLQKELQIEY----------SRCEALLAQERGQ--
-LAELQKSLDAER-NRTLEL------SEALQHERLLTEQLSRRPQETQA-----------
---HHALLRKLKEEKCRVSELQALLDRVQQQAAHTQRQLEAEVQ-KRCEELGKE------
------------------------------------------------------------
-------------KERELELQRQRDEHKIKQLQQT---VRALESKETLPCAAGSRLS--S
--------PRRAGGS-----ELDCLQERHQELEKIRQQLLGAAVLLTGFINQTVDRTIKD
WTSSNEKAVTSLLHTLEDLKSELST---SPS--SQKTAAELQM-QLVDVLLK-DNDSLTK
ALNTVTREKAELCKAVSRLE---KT--LKHH----L-------HRG-C--TLSK-SDRSA
WKPEGTALQISPARPTP--------------AASQEAN-TCNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKA--SASRPFTKFRTAVRVV
IAISRL--RFLVKKWQEVDRKGTL-TQGKAPR--PG-----RR-----------------
--------------MSRQQQRHFPPETRESSPPQNTSSGPTGD-----------TARGPG
PAAAPPGRRERSTPSPNSRLERSLTASQDPEHSLTEYIHHLEMIQRRLEGVQPD--STS-
KKSCRQKIKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DCALRG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQRGMFTVVEPPSQKQAWD----------------VHS---KGPPSRTA-
------------------------------------------------------------
----------------------VMFTVSDP-PSRTAW------DLHS-RDHHPERV--GI
LQFSDPPSQKRGIFTVSDPIQNSVGRLHISDPHQQKQRGSFTVSD----------PHPRM
TVFS--------C-------------------------EC-----WTTFFECK-QECELA
ITDLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIEKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASADALLDPVE-------VGLS----CVGLEEKPE--KERKDHVDELN---------
----PERHKESLPCFQAELEESHRHLLEAPESPLCIQR---EGHVSDRRCAE------TS
ALGQGW---R---LEPS--EGRSQGLPWVHLQGVQDRALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPT-------AQDGELA
ALHVKEDCALQLILARSRFLEE----------------------RKEITEKFSAEQDAFL
REAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTEHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KQDSLHQTILSQELEKLKQKHDEELQSVRDGLRTAAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------EAHQGEFGSEKKAALHEKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPAQEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHCLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
MDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNINIRKKMAELQEEVEKQKNIVKELVQDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSALLQRESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLDL-KNSQTAVRLGELQEESVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRCVLEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLHVLHQRFLRCQVELDRRQAYRTTAHTR----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMTLEDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPTDACDASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SMLGGSCHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-SLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQP-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRTAVEKDVED
FITTSLDSQETLSSS---------PPGLEGKTD-GSEKSDGSGFGARLSLGSGGPE----
---------APTAGPVT----PAAISGRFQPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVQEDLLYGG-K----------
TQFCFDVPTVCPDWRGELLQVVQEAFE--KEPEIQGVELQPRLSG-SDLGGHSFPLERLE
KVISEQGD----LQEKSLEQLRLPDRSSLLSEIQALRAQLRMVHLQNQEKLQHLRTALTS
AEARGSQQEHQLRKQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQESERLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
EGQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKASRRSMEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIQQLQQT---VRDLEPKDEVP-GSRLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLCAAGLLTGFASQAMDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTCS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
VAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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--------------------------------------------M---QQPVPALELEAL
RLSLSNLHAAQLERTQATLQREKEAALTELRATLNGRHAQELALLQSRQQHEQALAREQH
AQERQE----MELRCRQETAELKEKLQLEME-KNARMLENLKQGCEAEREL---------
---------------CLENLRRELSAKHRLELENLQDQFKNEL--------AEQKAELEK
IFQAKNQAECA-LRTLETQQDAALRQLREDLQSESGRHVRDLEQRLRDQEAAKQ----LE
LESLRASYAALKAQSQEEIRRLWSQLE-----SPGRDSHDPS-AFHDQLPARTPHGEEQE
HRRWDRRQR---------QQREESVPE---------------------------------
-----------SAQ-------VSAP----GLSLEERT---GEGTAHLE-----------G
PRLQPELEENHRSP----------SSLEARQQVGHEGT---P------------------
VSD--------GEQRVGLSEGPREELARAPLPCVPDMALQVEAEVAARVLR-LETEHKLK
LSLLQTE------LKEEIDVLKLENGSLR-EKLQQAISEKEHWERVKCELVEGHQEELKR
AKEKLELMKQESRDREAGWKVAREVLKREAEEERTLALLQLREQAEAETQSLVTRFELRE
LEMRRLQDQQAA------------------------------------------------
---QIRDLEESLLEQQGRLRQLELGLAGEECP---QCG---GEPGG----RPADQGGELA
MLRLKEDCALQLMQAQNRFLKE----------------------RKEITEKFAAEQDALL
REAQEKHSREL----Q----LLQERHQRHVLSLTAELEAVRRAEQEELRASMEGEQRALA
QAREAELQAGHAAALRALEARHSSHLDSLESRHRSEVQALREQHRRALEQLSAELEKQRQ
HKDASCPAVPTGER-------GQELLPADGGVTAQTEA--DPGAAGVALL--YPAL----
------------------------------------------------------P-----
------------------------------------------------------------
----------------------------AGQQGESEGEKKAALHEQEEIPRLECEQAPSP
GQKEEECLF-LQLQEKNDQILRLKDQIL-SLSQEVGECHSELEKLQQRRERENQEGTNLI
SMLKSDVDLSDRERRALRDALRRLLTLFGETLRAAVTLKSRIGERVGLCLEDEGLPDARP
SGQAL---------FAAPVLDETWPASEAAL------LELDRTLPEYA------------
---EESSEAEISSHICESFFMSPESSLECEQPVRKLYRSLGLAVDGLLERALDCTRQLEE
ARQIHSRFEKEFICKNEE---VVRKHQELLERLEEASAARTQLVLELHQAQGIIEGFKVE
KTGLQEALGQKEAAEQGLAVELESLRQQLQRAA------RQQAELEEENSALCAQKEALA
AEAGEREA------------ALRRDVDSLTQEQAEARKQSEKDRAALLSQMAVLEAELEE
QLARQEASAQQAEE-LRALRQQLAALDKQLRSQRQFMDEQAVEREHEREEFQREIERLEE
QLRQA--ARPRPRGSYVCD------QEQLDEEVKLLQEKLQEKSDGFNELAAKKELVDRQ
MLVQDEEI-------RRLEETNACCRREAAVLREELERQRDAVKALQQDKEMLEQ-QTSQ
LLLVSTL---------QPVPPAGSR-PEGPKVQLDAVQSALRQREREVLDLREQLERIKD
DFARKSDEVLQLNAKLGA-QCSRAAAGAQELQEENASLKAFL------------------
--------QSKEEEMVRVSEQLGAQLAGMGSGALGEVPCDRSSEVEELRSIIENLRENQQ
RLQREKVEETERLHEVIERLQRELSLGGPAGSGVESGQ----------------------
-----------------------ALAVPAVGPEALAAAGATGQLLAEQERRHGQALEALQ
QRLRAAEEAAATRLADL-----------------ERCAAHGEAEVRGLAAQIQAFEAALE
AKEAGIAERDSEIDAMKQQKLAQSAELEALLAA-FSHFRLALEQ--------QPLAAETE
GEPPELRRLRVQCVRLGRQLQLLHLRFLSCQGQPDGQQAPRVHLHPH----------VEG
CPQGQSPRAAGASWDEESQPP--------TAPQGR--AGDAQRAAP-------EDLQLAK
APECFHHPALHR------RDSVMSV-LAACQKQLQSEL--LLAEK-----EMHVRTEDGG
PGPGGV----------------------QNKGKV-LEDCQPWKVGLLSQVKELQEKLNHL
LNSVNFQNTETEGFRLQQPVAS-PRAPENSWS--DCS-----------------------
-DNGEGTDKS-LVDASGIGKTT---------------------CDLI-------------
--D-------LSGSQDPLIKN-EMSDVPEQDQVDLQDGSPCLQA----------------
-----------------------------GFHGGSHDLAHPERPGPLKNALRAMDLSSWS
SPEVVRKDS-TLEPAPS---LPLTPCSDSLS---LDASLQDRTSA-SLQA-DQVELLGYL
GGSA---AGKASRWAASPL-----------------AADRAPSAD-RHVQWMSVEKDVED
FIVTSLDAQEKPRTC---------PLGFEGKNN-GSENSDGSGFGELLNQGSGRLD----
---------ASTASPAV----PPPASGRFQQPLEAMKEK-GVHPKQVKALLQMVCDESQH
ILALSERHGPPSTLSKGE------------PSAPLECFPREGSRLLEAVPALRRHETLAL
HKGEKEPPDTCLDWR-EFLQVVQEASG--REWEVLRAELQPQACA-PDPGDHSSLLQRLE
KVVQE--------QEKSLEHLRLSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCGALTS
AEARGSRQEHQLRRQVELLAYKV-------------------EQEKRIASDVQKTLKEEQ
EKAGSARKLLAVEQTAVRDLRAELRECKQDNERLLASLSEAQKEVLQLR-----------
-----------------SVLDGKESSLKA-------------ALQELECE----------
--RGKEHALRGRLEEQRL---------------------RHLREEGQSSKTLE-ELRTAL
EQQCAQS--SRLRVALEHEQTA-TDNLRRELQIEA----------SRCEALLAQEQGQ--
-LCELRRSLEAEK-GRSREL------AAALRHERLLTEQLSRGARD--------P-----
-PAQQAPPRRSRDERARVPEPQARLEQMQQRAA----------------ELE--------
------------------------------------------------------------
-----------RDKERELELQRQRDQHKIRQLQRT---VQALEAKEAA------------
-------------CQAP---EAERLQEERLGLEKVRQQLLCAAGLLTNFVSRTVDRTISD
WTSSNEKAVTSLLCTLEELKSELSTPGSS----QRKMRAELQT-QLVDVLLK-DNDSLTT
ALRTVTQEKAELCRAVSQLE---KS--LKQHLLRR--------------GVCSR-PDKSA
WKQDGAGSQSSARQPDPALPAP---------AAREEAS-SGSVQVEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TPSRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGAIML-GRAPR--PAVAGEGVPV-PRQQAP---------
-----------PKTSTSPPTRDVSSSHAGDRV----------------------------
-PKASPRRRERSTPSLDSRSERSLAASQDPERSLTEYIHHLEMVQQRLAGAPPD--SAS-
KRSCRQKTKQ--------

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------------MEDEQEQRRRKVEAGRAKLANFRQRKTKGDCPNSKKKTAK--------
------RKGSAVHASVQEEG--SVATP-NSELPQ-GGA--VFESQSCS-------NTLEG
ARGASA----AQEQED-----------------CELDVA---------------------
------------------------------------------------------------
-----------------------------------------------------DM-----
------------------------------------------------------------
------------------------QGQQQ----PQPQP-QPPQ-----------------
--------------------------------------------------TAHNLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQH
AREKEEM-AEMALRSGQEAAELKEKLRSEME-KNVQVIETLKQDWESEREL---------
---------------CLENLRRELSLKHQSEMEGLQSQFQKEL--------SEQKVELEK
VFQAKHEAEVS-LKNLEAQHQAAIKKLQEDLQSEHCQYLQDLELRFREKEKAKE----LE
LETLQASYEDLKAQSQEEIRRLWSQLE-----SMKTNSEELN-GSWEPLLAQTSHLEELE
HLRSGFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR
LQEARED-SLESAE-------ISSS----CMFPEETSG--RERKEPPDALDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLGQPKVQDSLVEDCQVKLTK
AEEKIQQMREEFQKKEAEWELSREDLKREAEERLASMFLELREKAESEKLSIISRFEHRE
SSMRHLQDQQAA------------------------------------------------
---QILDLERSLTEQQGHLRQLEQELTRDDGL---PCNQCGQDPAV------VQDGKNGA
LLREKNDCALQLLMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDTQEKHSHEL----Q----LLQQGHQQQLVDLRRELETKHCSELTEQLASLESRRQALL
ETHVAELQVKHNAEISALEKRHLSNLDELESCYVADIQTIRDEHKQALELLRAELEEQLQ
KKESCHREILTQELEKLKLQHAEELQSLRDSLRMEMSA--QHTENGRGLAS---DVQGAH
QQDPAVALHN---EGRLLAEDGGAALGH---------------VDAEGLL----H-----
------------------------------------------------------------
----------------------------QAGPQKLG-----------EAHTVEMQKSQ--
----AELAKPQEQQTSQDQVAQVRDKVF-LLNRELEECRAELEQLQQRRERENQEGTTLI
CMLRADVEQAQGEGKALRDTLRRLLDLFGETLKAAVTLKSRISERAGLLLDHEDATDT--
-SDAR---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTAVEGLLEMALDSSKQLEE
AHQLHRCVEREFRHRNEEMAQAVQKQQELLERLREESAAKDGLALELHTAKGLLEGFKVE
KVDLQEALGRKEESEQQLILELEELRKQLQQAA------RELLTLKEEKSVLWNQKETLT
SEAKERE------------AALQKEVESLTRDQWESRKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLAEE-VATLKQQLAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--ARPRPPGPQDSQ------CVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQ
LLLQEEEI-------KRLVETNASAQRQMAQLQEELGKQRKSMEEL-KKKEMLKQEHMAD
SLLTPASR-ARLDEAGGPMLSQGSS-SRGPEAQPDGTERTLLQHKN--------------
------------------------------------------------------------
-----------------------------------KVVHSRNSEIEELKSLIENLQENQR
QLQKDKAEEIEQLHEVIEKLQSELSLMGPKAHEVSDPQAGSLH----SELACLQAEGLG-
-----------------------GQALRNELQAAQAAKEVFGQLLADQAHGHSQALEALQ
QRLQDAEEVAARHLAEL-----------------EHCVALREAEVEAMTCQIQEFAATLK
AKEAIITQRDLEIDAMNKWKVSHSLELEAILLA-LAHFRHALEQ--------QTRATP--
DEPPELRQLRVQCTRLSHQLQVLYQPFLKCQMELDQHQPHVASIGC--------------
----ANP------CA------D--------------------------------------
--------DELE------QEGGSSR-LAL---------------------------APHS
L---AA----------------------QAKEEE-LEDCPLGKANLMAQVRQSQEELDHQ
VHSVASRDTNMETCKLQQ-----PNLLKNGSS--NHC-----------------------
-YNGDESKPSPSDDVLNIAKNT---------------------WDVI-------------
--D-------IIKNQDLLVQI-EMSEFPTQENLPSQAS----------------------
-----------------------------GHSSGS--LLPEEAAGPQQDPVRALDLSSWS
SPEVVRKDP-SLEPQHS---LPLTPGVGTVSLHSVDI-SPDWTNP-LLQA-DVSGLLCYP
GKSA---SGQAPLWAVA------------------------PSAGKHHAERTATEKDVED
FIVTSFDSQESLTSP---------SHELARRSD-GSGKSDGPDIAMMLTLGSEGSE----
---------TPTTDLVA--AAAVPFSRRSVQSPGAMKEK-EVHAKQMKALLQMVFDESHQ
ILALSESQDPSSALSKGE------------PRDPLDGFLRDSQALLEVTT----------
DRGDKESLETHLTWSEELLRAIQEVFA--REQV--NAELQPRPYG-SNLGDYNSLVKRLE
KVIQEQGD----PQ-KVQEHLCLPDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIANELQKTLSKEQ
ETASDVRKRLMVEQSAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRYGHVTW-----
-----SYCGTSSASTGRAVLDGKENELKI-------------VLEELESE----------
--RGKGQALQAQQEEQQL---------------------RYLQREGQNSRALE-ELRLSL
EKQLAQN--NQLCVALKHERAA-KDNLQKELQIEA----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SHSLEL------SEALQHERLLTEQLSRNAQEAWAR--QET-----
-QVQHALLRKLKAEKTRALELEAMLEKVQKQAA---------------------------
---------------------------------------------HTQQQLEAQAQ----
----ERCVELRREKERELEIQRQRDEHKIEQLQRL---VRELRWKEEAPGGNGPCRGSPG
----RG---------SL---ERDQFQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSMPTSF----QKKMTAELQV-QLMNELLS-DNDALTK
AVGMASREKAELCRTVSRLE---KT--LKHHTQKG--------------CVLSR-QSKSS
LKQDGTDLQSSLRHSDPEWHSQ---------TTSGDTN-TCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TMSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALIH-GKSTR--HGH-----RTSQRQRSP---------
-----------SGTRASLPTRDTSSGPTKDSRH-----------------------SPRS
AAAVSLGK-ERSASTPSSRLERSGTASRDPEHSLTEYIHHLEMIQQRLGGLPPD--S-T-
QKSCHQKIKQ--------

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--------------MR-----------------RP-------------------------
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--------E-DE------------------------------------------------
------------------------VGTQQP-VEMWQVQ-LQTQ-----------------
--------------------------------------------------PVPSLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELGLVREQH
AREQE----AAALRYSRETAELKEKLQSEME-KNVRMIETLKQDWESERGL---------
---------------CLENLRRELSAKHRLELENLQDQFKKEL--------AEQKAELEK
IFQAKNQAEIA-LRTLEAQHDTDMRKLREDLQSERCRHLEDLELRLRDQEMEKQ----RE
VESLRASYEELKAQSQEEIRRLWSQLE-----SVRPDRQDLT-ELPDQLLAHVPHVEGLG
HLKQDFQQQQQQQQQQQQQQREK--TEHESELEQLRIYFEQKLKDAEKSYQEDLILLQQR
LQEANEESFLESVD-------ISA-------FLEERSE--KRRREHVDGPSLQ-------
----SELEAAH------------WRQLAALKSSLE---GRQEVDLAG----P------QV
-ME--------GEQHTGFSEGPDEELARVPLLCAQDTASEVETEVAARVLS-LEAEHKLK
LSFLQSE------LKEEIDVLKLENRNLH-ERLRHEIRLKEDLERVKYNLVEDHQEELKK
AKEKIQLMKQEFKEREEEWKVTSEGLKRKAEEEVTLMLLDLREQAESEKQLIINKFELRE
IKMRQLQDQQAA------------------------------------------------
---QILELEGSLVEQQGRLRQLELGLAGDEFP---QCSQCGREPGGG--LAPVDKDWELA
TLRLKEDCALQLMLAQNRFLEE----------------------RKEITEKFTAEQDALL
REAQEKHAHEL----R----LLRERHQQHVLSLTAELEARHRAQAEELRASMESEHWALS
EARVAELRTKHAAAVSALEASHSSHLDSLESRHRSEMQAVREEHRRALEQLRAHLAEQLQ
EKDASHPAVLAREP-QDELNRGRDLPPVEDSLRTPGST--SCSEDGKALAP--HELWGAP
QSTLVPVEV--EAQGPALRAELHEEEE-----K-----RQLSKS-QSEVVLEQQI-----
------------------------------------------------------------
----------------------------PQPKGEFESEKEVALHEQEKIHRLECEQVQSL
YQKEKESL-FLQLQEKNNQILQLEDQIL-SLRHEVEECHLELEKLQQRHERENQEGTNLI
SMLKSDIDLSDRERRALRDTLRRLLGLFGETLKAAVTLKSRISERVGLCLEDESPHEVRP
SGQGP---------SAVPVLEETWPE--AAL------LELDRTLPECA------------
---EVSSEAEISSHVCESFFMSPENSLECEQPIRRIYRSLGLAVDGLLELALDSTRQLEE
ARQIHSRFEKEFSCKNEETAQVVRKHQELLERLDEENAARTRLTLELHQARGLIEGFKVE
QASLQEALGQKETAEQGLAIELESLRRQLERAT------QQQAELREENSVLWTQKEALA
AEAGERE------------DALRREVECLTQEQLEARKQSEKDRAVLLSQMKVFEAELEE
QLSRHEACAKQAEE-LSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEE
QLRQA--ARP--RGPCVRD------E-QLDEEVELLQEKLREKSDGFDELVIKKELADRQ
VLIQEQEI-------KRLQETNASCRREATELREELEKQRNTVKALRQDKEALQEQR---
-GVVSTLQ-SKLDEGSCPTPPAGTC-PESPEVQLEAVQTALRQRESEVLDLKEQLGKIKD
DLVSKRDEGLHLNVKLDT-QSSRASVSLRELQEENARLKAFL------------------
--------QNKEKEIMCVSEQLEAQLAGMGRGTLGEVPCDRNSEIEELRSVIENLRENQQ
QLQKDKAEEMEQLHEVIERLQRELSLGGPAPLGAQVSE---LPGDPVASP----------
--------------------------------EALVATGPAGRLLSEQERRHGQALEALQ
RRLQAAEEAAARKLAEL-----------------EHSAALREAEVQGMASQIRAFEAALK
AKEAKIAERDLEIDALKQQKLAHSAELETILSA-FSRFRRSLEQ--------QPLTAE--
DEPPELQRLRAQCVRLSRQLQVLNQRFLRCQKELDKKQARGAPLHPR----------VDG
SSQGRGPGGEEASDDKASGQDV-GTAPNSR----V--G-DPQSAVN-------GDLQPAK
APVTPDHPGPHR------QDRVTSV-LAACQKQLESEL--LLVKS-----EMHLRMDDRG
KVPGRM----------------------KNKEKL-LEDCQLQKVGLISQVKELQEKLNRL
MHSVNFQNSETEDFKFQQPLAS-SHALENNLS--DSS-----------------------
-SNGEETDKLPLVDAFHIDKTT---------------------CDLI-------------
--D-------LSGNQDSLVRN-EMPNVPMEDRVDLQDGSLCLQV----------------
-----------------------------SLHSGSHDLTHTQEPGPVKNALRAMDLSSWS
SPEVVRKDS-TLEPAPS---LPLTPCSDALSL---DASGQDRTSA-SLQA-DELDLLWYL
GGSA---AGKASRWAESPL-----------------VVDRAPSTD-HHVQRTAVEKDVED
FIVTSLDTQEKPRSS---------PVGFEGKNS-RSDNGDGSGFGDMLSQGSGRLD----
---------APTASPVV----LLPASGRFPQPLEAMKEK-EVHPKQVKALLQMVCDESHH
ILALSEYRGPPSALSKGE------------PSASLERFPREGPGLLEAIPALRRHPSPTL
LKGEKEFPDMCLDWRGEFLQIVQEAFG--KEREMLRAELQPRPCG-SDPGDHSSLLQRLE
KVVQEQ--------EKSLEHLRLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEARGSRQEHQLRRQVELLAYKV-------------------EQEKRIASDVQKTLNEEQ
EKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLSEAQKEVLQLR-----------
-----------------SVLDSKESNLKA-------------ALQELESE----------
--RGKERALQSRLEEEQL---------------------QHLQREGQSSKTLE-ELRLSL
EKQHAQS--NRLCVALKHEQTA-KDNLQKELRIEA----------SRCEALLAQERSQ--
-LSELQRSLEAEK-DRSLEL------ATALRHERLLTEQLSSRAQEA-------------
-PAHRALLRKLKEEKSRAAELQ--------------------AR-L--EQVQR-------
-------------------------------QLVA------------------DVQ----
----KQRAEIEREKERELELRRQRDEHKIRQLQRT---VQDLEAKEEARQRQ--------
---------------CP---ESARLQEQRLSLEKVRQQLLWAAGLLTSFVSQTVDRTIGD
WTSSNEKAVTSLLHTLEELKSELSAPNFS----QKKMPAELQV-QLVDVLLK-DNDSLTK
ALCTVTQEKAELRLAVSQLE---TS--LKQHLLKG--------------RVRSR-PDRSS
WRQDRAVSQSSPRQPEAGLPAS------------EDAN-PCSMQMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--STSRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGAVVQ-GRAAR--PGFL------MPRQQPP---------
-----------PKTSTSPPTRDASSSHTGDPVP---------------------KASPC-
-------KRERSAPSSNSKSERSLTASQDPEHSLTEYIHHLEMIQQRLGGAPPD--CTS-
KKSCHQKIKP--------

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-----------MEEDEQEQRRRKVEAGRATLAHFRQRKTKGDCVHSKKKTAK--------
------RKGPPVDAPVQEES--PLVTQ-DGGLLQ-GSG--ACRSTAGS-------DSPDR
ARGAFA----TQE-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------QDQ
DCESMGIPEDKAGQQQ----------------------------Q---PQAAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQSELELVREQH
AREKEA----MALRCGQEMAELKEKLQSEVD-KNAQMIETLKQDWESEREL---------
---------------CLENLRKELSARHQSEMEDLQNQFQKEL--------AEQRAELEK
VFQDKTEAEVS-LKSLEAQHQAAVRKVREDLQLEHCQYLENLELKFREKEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLE-----SAKTSREEMH-EPWPPPLAGVLHMEQLE
HLRQEFAQQ---------QQQDR--AQHESELEQLRLYFENKLRDAEKTYQEDLSLFQQR
LQEAKEDSLPGSVE-------ISSS----CAFLEDTSD--REGKEHPDQLNLQ-------
----LEQQEGSVACLQPGPKEKHR-LGSDLCSSLHVLR---EEDESDRGL----------
--VGPE-VLEWEPFRAVLSDQHSQEPAQVQPQCMQDTAVEMDAQVTARVLG-LEAEHKLK
LSLLQTE------LKEEIELLKMENRNLR-EKLQHETRLRGHLESVKFSLVEDHQAELNK
AEEKIKLLKQEFKKKEAEWEITHEDLKREAEEKVTSMLLELQEKAELEKQSIISRFELRE
AEMKSLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLRQLEQGLAGYDAL---LCSRCGREPPVAQ-HG-----GHPI
PL-REEDCALQLILAQNRFLEE----------------------RKEIVEKFAEEQDAFL
RDAQEKHAQEL----Q----LLQQRHQQRLLSLRTELESKHQAELAELMATLESEQQVLL
ETRVAELQMKHAAEISALETRHLSNLDALESCYLSEMHTVRDEHRRALELLQTDLEEQLR
KKDSFHQVILTQELEKLKQKHDAELQSAKDSLRTEMST--IHAEQLEVLAR---ELQGTH
QGKFESEQKA---A---VSEEEVHRLEHES---------------VPGL-SQEQD-----
------------------------------------------------------------
------------------------------------------------------------
---------LPPL-QEDSQTQQLKGQVL-SLSREIEECRTELERLQQRRERENQEGATLI
SMLRADVDLSQGERRALHDALRRLLGLFGETLKAAVALKSRIGERVGFLLDHTGTTAA--
-DQAL---------STAPALEEVWSDDAAL-------LELDRTLPEGA------------
---EMSSLADISSHVCESFFMSPESTLECEQPIRRVYQSLSMAVDGLLEMAVDSSRQVEE
ARQLHSHFEKEFSHKNEETAQVVQKHQQLLECLQAEGAAKAALALELHTAEGLLEGLRVE
KADLQEALARKEASEQQLVLELESLGQQLQQAA------KEQAGLREEHSLLWSQKEAQA
VEAEARA------------AALQKEVESLTREQLEARRQAEKDRAALLSQMQILESELED
QLRQHQGCARQAEQ-AATLKQQLAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQKLEG
QLRQA--ARLRPPGPHDQ--Q-----------VELLREKLREKSDGYNELVIKKELADRQ
VLIQEEEI-------KRLEEINAHTREQMALLQKELEKQKEMVKEL-QDKEALTEPQTSE
LMPAPMSQ-PGPDEGRCPVLPLGSL-CEDPEGWPEAVQRVFLQDG---------------
------------------------------------------------------------
----------------------------------DEVVYHRSSEVEELKSIIENLQENQE
RLQKDKAEEIEQLHEVIEKLQAELTLLGPVVHELSDRQADSLHS----ELLCFQAEGPGG
Q------------------------ALQGELEAALVAKETLAQLLADQAHGHSQALEGLQ
QRLQAAEEAATRQLAEH-----------------GHNMALREAEVKGMTSRIQEFEAVLK
EKEAVIVQRDLEIEAMNKQKEAHFIKLEAVLSA-LARFRHALEQ--------QPPASS--
-EPPELQWLRAQCVCLSRQLQMLNQRFLGCQVDLDKQQARGVPE----------------
THPHPHVDTKSADLLEQGGGS----------KLLA--SDPHGRGSQ-------DDPQPAK
VLAMLKDAEFHK------PESVVSV-LTVCQRQLEAEL--LMVKN-----EMCLSMEDDP
RAPGKR----------------------KGKEKW-MEDGHLQKVDLIAQVQQLQEKLNCL
AHSVALQDMDPIGSRFQQPSAL-TYLSENS------S-----------------------
-HGRAEADTLPPVHSLNSDETT---------------------WDLT-------------
--D-------TTKNQDALSRN-EMPNSLIQEKIEPQDGRLSLQT----------------
-----------------------------SMHDG---SLHAEEAEPLKDPGRVQELSSWS
SPEVFRKDS-SLEYWPSI---PLTPCSGAVSLRNAEASPQDP--SWLLQS-SL-------
GGS---TEEQTPLWT---------------------ATLPS---D-QPVGRIAAEKDVED
YIATSFDSRDVLRSP---------PPGLEGRSD-ESEKSDGLGCGVRLNLGSRGPA----
---------TPTTGAVTPAP----VSRGFQQPPGVVQAK-EIHTRHVKALLQMVCDESHQ
ILALSESRDLPSTLSKGE------------PCTPLTCFPSEGQGLLEVAP----------
KKGEKELLDSRFDWRAEFLEATQ-MFE--KEQNMVQAELQPRPCV-SDPWGHSLLCRKLE
KVAQEQGD----PQEKPWEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEARSSRQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLSEEQ
ERARGVRQLLAVEQSAVQDLQSELRECQQENARLLESLGEAQHEVLQLR-----------
-----------------SLLDGKESDLKA-------------ALEELEQE----------
--RGKERALQARQEEEQL---------------------RHLQREGQSTKALE-ELKVSL
EKQFTEN--NQLCVALKHEQTV-RDNLQQELQIEH----------SRCEALLAQERGR--
-LSELQRSLEAEK-NHAREL------SEALQHERLLTEQLSRGARHPQA-----------
---HHAMLRKLKAEKARVLELQVALQVAQQQVLQAQQQLEAQVQ-EHYTELGRE------
------------------------------------------------------------
-------------KEQELELQRQRNEHKIEQLQQT---VRELQSKE--EVPLGSGPFLDS
----------------L---ELSSIWEQQQGLEKIRQQLLCVAGLLTSFVNRTMDRTLND
WTLPSEKAVSSLVQTLQGLKSELSMSASSQK--K--MAAELQV-QLVDVLLR-DNDSLTK
AISTVTQEKAELCKAMSRLE---KT--LRHHVQKGC--------------ILSR-SSRPA
WRQDRTVSQSWPQHPDSGRPTL---------AASEEAN-TCNIKVEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSRADKKM--STSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGASLLQGKAPH--PG-----PRVPRKQLSL---------
-----------LETRESPPTQDVPSHHARDSA----------------------------
--CRSPSGRERSSPSPSSRLERPLTASQDPEHSLTEYIHHLEMIQQRLGGAPPD--STS-
KKSYRQKIKQ--------

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------------MEAEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAK--------
------RKGSAVDASVQEES--PVTKE-DSALCG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQPEDCDGEKREDLEQLQQ----------------KQV---NDHPPEQR-
-GMFTVSD----------------------------------------------------
---------------HQPEQ-RGMFTVSDH-QPEQRG------MFTV-SDRQPEQR--GM
FTVSDRQPEQRGMFTVSDH--------------PPEQCGMFTISD----------HQPEQ
RGIF--------T--------IS-D--------HPAEQRG-----MF-TKECE-QECEFA
ITDLESSREDEAGLQQ--------------------------------SQAMHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAERA-LRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDSVE-------VGLS----CVGLEEKPE--KGRKDHVDELE---------
----PERHKESLPRFQAELEESHRHQLEVLESPLCIQN---EGHVSDRCCVE------TS
ALGHGW---R---LEPS--EGHSQELPWVHLQGVQDGDLEADTEVAARVLG-LETEHKVQ
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKDDLEKVKHNLIEDHQKELNN
AKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQDLTSDDAL---HCSQCGRETPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHAREL----Q----LLQKRHQQQLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLR
KKDSLHQTILTQELEKLKRKHDGELQSVRDHLRTEAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GVHQGEFGSEKKTALHEEEETLRLQSAQAQPF
HQEEKESLS-LQLQKKTHQVQQLKDQVL-SLSHEIEECRSELEVLQQRRERENQEGANLL
SMLKADVDLSHSERGALQDTLRRLLGLFGETLRAAVTLRSRIGERVGLCLDDAG---A--
-GLAP---------LAAPVLEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLMEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESTAKAELALELHKTQGTLEGFKVE
TADLKEALAGKEDSEHRLVLELESLRWQLQQAA------QEQAALREECTRLWSRGEATA
TDAEAREA------------ALRKEVENLTKEQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--AKPQPWGPRDSQ------QAPLDGEVELLQQKLREKLDEFNELAIQKESADRQ
VLMQEEEI-------KRLEEMNINIRKKVAQLQEEVEKQKNIVKELEQDKEVLKKQQMSS
LLLASTLQ-STLDAGRCPEPPSGSP-PEGPEVQLEVTQSALLRHESEVLDLKERLEKMKG
DLESKNEEILHLNLKLDM-QNSQTAVSLRELEEENTSLK---------------------
------------------------------------VIYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GV--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHSQALEALQ
QRLQGTEEAAERQLAEL-----------------ERNVALREAEVEDMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKAAHSAELEAVLLA-LARIRRALEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATVHTR----------VPG
AHPQPRMDGGAKAQVTGDVEA-------SHDAALE--P--VVPDPQ-------GDLQPV-
-LVTLKDAPLCK------QEGVMSV-LTICQRQLQSEL--LLVKN-----EMRLSLEDGS
----------------------------KGKEKV-LEDCQLPKVDLVAQVKQLQEKLNRL
LYSMTFQNVDAADTKSPWLVAS-AHLLESSWS--DDS-----------------------
-CDGEEPDISPPVDTCDANTATG---------------------GVT-------------
--D-------VIKNWDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SVLGGSRHQSHTAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLGDRADTSLPQT-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HHVQRMAVEKDVED
FITTSFDSQETLSSP---------PPGLEGKAD-RSEKSDGSGFGARLSPGSGGPE----
---------ARTAGPVT----PAPISGRFQPLPEAMKEK-EVHPKHVKALLQMVRDESHQ
ILALSEGLAPPS----GE------------PHPPRKEDEIQDSSLHGE-K----------
TQ---EVPTACPDWRGDLLQVVQEAFE--KEQEMPGVELQPRLSG-SDLGGHSSLLKRLE
EIIREQGD----LQEKFLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALRELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQRDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQ-KHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPA
AAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEAMRQRLLSATWLLTSFASQAVDRTVND
WTSSNEKAVMSLLHTLEELKSDLSRPTSS----QKKMAAELQF-QFVDVLLK-DNVSLTK
ALSTVTQEKLELSRAVSKLE---KL--LKHHPQKG--------------CSPSR-SERSA
WKPDEKAPQSSLRRPDPGRLPP---------AASEEAH-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFTRFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAPR--P-----GARARR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GRRL
AAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPD--STS-
KKSCHQMIKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQLEDRDGEKREDLEQLQQ----------------KQV---SDHPPEQR-
------------------------------------------------------------
----------------------GIFTVSDP-CQEQRG------IFTV-SDRHPEQR--GM
FTVSDHPPEQRGMFTVSDPHPEQRGMFTVSDH-HPEQRGIFTVSD----------PHPEQ
RGIF--------T--------VI-S--------DPHPEQR-----EVITKECK-QEFELA
IADLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIEKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KERKDHVDELN---------
----PERHKESLPCFQAELEESHRHLLEAPESPLCIQR---EGHVSDRRCAE------TS
ALGQGW---R---LEPS--EGRSQGLPWVHLQGVQDRALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPT-------AQDGELA
ALHVKEDCALQLILARSRFLEE----------------------RKEITEKFSAEQDAFL
REAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALRELTASLESKQGALL
AARVAELQTEHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLQTAAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKAALHEKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGANLL
SMLKADVDLSHSERGALQDTLRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPAQEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
TDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QTPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNINIRKKMAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSALLQRESEVLDLKEQLEKMKG
VLESKNEEILHLNLKLDL-KNSQTAVRLGELQEESVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRCVLEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLHVLHQRFLRCQVELDRRQACRTTAHTR----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMTLEDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTLQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPTDACDASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SMLGGSCHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-SLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQP-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRTAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGARLSLGSGGPE----
---------APTAGPVT----PAAISGRFQPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVQEDLLCGG-K----------
TQFCFDVPTVCPDWRGELLQVVQEAFE--KEPEIQGVELQPRLSG-SDLGGHSFPLERLE
KVISEQGD----LQEKSLEQLRLPDRSSLLSEIQALRAQLRMVHLQNQEKLQHLRTALTS
AEARGSQQEHQLRKQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQESERLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENKLKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
EGQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKASRRSTEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAMDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
VAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------LTPDG
AGWASA----AQLEDQDGGKREDLEQLQQ----------------KQI---SDHPPEQR-
-GIFTISD----------------------------------------------------
---------------HHPEQ-CGIFTISDP-HQEQHG------IFTI-SDHPPEQR--EI
ITVSDHPPEQPGIFTVSDPHPEQHEIITKVFFK---------------------------
----------------------------------------------FCVKECE-RECELA
IADLQSSREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARAAHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGYA----KQL----PF--R------GHFV---------
----GDFAPESLPCFQAELEESRGHLLEAPESPLCIQH---EGHVSDRCCAE------TL
ALGQGW---H---LEPS--KGHSQELPWVHLQGVQDGALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKAKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVTKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRK
AEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQELTSDDKQTIVNKFELRKAEMRQLQDQ
QAAQILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGRELPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIRTIREEHRRALELLRADFEEQLQ
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLQTAASR--EL---PGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQVEFGGEKKAALHEKEETLQLQSAQTQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEVLQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKEALAGKEHSEHRLVLELESLRRQLQQAA------QEQAVLREECTRLWSREEATA
TDAEAREA------------ALRKEVEDLTREQSEIRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNISIRKKVAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLSSTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQNALLQRESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLVM-QNSQTAVRLGELQEENVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSQLLADREHRHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRRALEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLQVLHQRFLRCQVELDRRQACRTTAHTW----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMMLEDAPLCK------QEGVMSV-LTICQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPTDACDASTAT---------------------GGVT-------------
--D-------VIQNRDSLIPG-EMPDFPIQEKSECQDRSLSSPA----------------
-----------------------------SMLGGSHHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQT-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRMAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGLGFGARLSPGSGGPE----
---------APTAGPVT----PAAVSGRFQPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPSRKGDEVQEGLLCGG-K----------
TQFYFDVPTVCPDWRGELLQVVQEAFE--KEQERQGVELQPRLSG-SDLGGHSSLLERLE
KAISEQGD----LQERSLEQRRLPDRSSLLSEIQALRAQLRMAHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANSVQKLLVAEQSVVRDLKSELCESRQENERLSRSLCEVQQEVLQLR-----------
-----------------SMLSNKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-FGELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDA-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVDALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAKAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQRT---VRDLELKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAVDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDILLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSVRLERAA
WKPDETAPQSSLRRPDPSRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--P-----GPQVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHIGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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------------MEDEQEQRRRKVEAGRAKLANFRQRKTKGDCPNSKKKTAK--------
------RKGSAVHASVQEEG--SVATP-NSELPQ-GGA--VFESPSCS-------NPLEG
TRGASA----AQEQED-----------------CELDVT---------------------
------------------------------------------------------------
-----------------------------------------------------DL-----
------------------------------------------------------------
------------------------QGQQQ----T--QP-QPPQ-----------------
--------------------------------------------------TAHNLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQH
AREKEE----MALRSGQEAAELKEKLRSEME-KNAQTIETLKQDWESEREL---------
---------------CLENLRQELSLKHQSEMEGLRSQFQKEL--------SEQKVELEK
IFQAKHEAEVS-LKNLETQHQAAIKKLQEDLQSEHCQYLQDLEQKFREKEKAKE----LE
LETLQASYEDLKAQSQEEIRLLWSQLE-----SMKTNREELN-GSWDPVLAQASHLEELE
HLRSGFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR
LQEARED-SLESTE-------ISSS----CVLLEETSG--REGKEPPDPLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLGQPKVQDSLVEDCQVKLSK
AEEKIQQMKEEFQKKEAEWELSREELKKEAEERLASMFLELREKAESEKLSIISRFEHRE
SSMRHLQDQQAA------------------------------------------------
---QILDLERSLMEQQGHLRQLEQELTRDDLL---PCSQCGQEPVM------AQEEKNGT
LLREKEDCALQLLMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDAQEKHSHEL----Q----LLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALL
ETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHKQALELLRAELEEQLQ
KKESCHREMLTQELENLKLQHAEELQSVRDSLRMEMSA--QHIENGKGPAA---DLQGAH
QQDPAMTLHN---EGHLLVEDGDAVLGS---------------VDAEGLL----H-----
------------------------------------------------------------
----------------------------QAGPQELG-----------DAHTVEMQKSQ--
----AELAKPQELQASQDQVAQVRDKVF-LLNRELEECRAELEQLQQRRERENQEGTTLI
CMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADT--
-SDAR---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTAVEGLLEMALDSSKQLEE
ARQLHRCVEREFRHRNEEMAQAMQKQQELLECLREESAAKDGLALELHTAKGLLEGFKVE
KVDLQEALGKKEESEQQLILELEDLRKQLQQAA------RELLTLKEEKSVLWNQKETLT
NEAKERE------------AALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLAEE-VATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEG
QLRQA--ARPRPPGPRDSQ------CVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEEEI-------KRLEETNASIQRQMVQLQEELEKQKKSMEEL-KEKEILKQEHMGD
LLLTTVSR-SGLDEAGCPMLPQGSS-SRGPEAQPDVTERALLQHEN--------------
------------------------------------------------------------
-----------------------------------EVVHRRNSEIDELKSLIENLQENQR
QLQKDKAEEIEQLHEVIEKLQSELSLMGSKVHEVSDPQAGSLH----SELACLRGEGLG-
-----------------------GQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQ
QRLQDAEEVAARHLAEL-----------------EHCVALREAEVEAMASQIQEFAATLK
AKEAIIEQRDLEIDAVNKWKVSHSLELEAILLA-LAHFRHALEQ--------QTCATP--
DEPPELRQLRVQCARLSHQLQVLYRPFLKCRMQLNQHQPHVASIGC--------------
----ANP------RA------D--------------------------------------
--------DELE------QEGVSNR-LAL---------------------------APHS
L---AA----------------------QDK-EE-LEDCPLGKASLMAQVRQLQEELDHR
VHSVASRDTNSETCKLQQ-----PNLLENGPR--NHC-----------------------
-CNGEESKPSPPDDVLNIAKTT---------------------WDVI-------------
--D-------IIKNQDLLVQV-EMPDFPTQEKLTSQGGPFSSQA----------------
-----------------------------SGHSSS--LLPEEAAEPQQDPVRALDLSSWS
SPEVVRKDP-SLEPQHS---LPLTPGVGTVSLHSVDI-SPDWTDP-LLQA-DVSGLLCYP
GKSA---SGQAPLWAVA------------------------PSAGKHHAERTATEKDVED
FIVTSFDSQESLTSP---------SHELARRSD-GSRKSDGPDIAMMLTLGSEGSE----
---------TPTTDLVAA-AAAVPFSRRFVQSPGAMKEK-EIHAKQMKALLQMVFDESHQ
ILALSESQDPSSALSKGE------------PRDPLDGFPRDSQALSEVTT----------
DKGEKDSLETHLTWSEELLQAIQEVFA--REQE--NAELQPRPYG-SNLGDYNSLVQRLE
KVIQEQGD----PQ-KVQDHLCLSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIANELQKTLSKEQ
ETASDVRKRLVVEQSAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRYGHVTW-----
-----SYCGTSSASAGRAVLDGKEKELQV-------------VLEELESE----------
--RGKGQALQAQQEEQQL---------------------RYLQREGQSSRALE-ELKLSL
EKQLAQN--NQLCVALKHERAA-KDNLQKELQIEA----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNSQEACAR--QET-----
-QVQHALLRKLKAEKTRALELEAMLEKVQKQAA---------------------------
---------------------------------------------HTQQQLEAQAQ----
----ERCVELRREKERELEIQRQRDEHKIEQLQRL---VRELRWKEEVSGGNGPCRGSPG
----RG---------SL---ERDQFQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSMPTSF----QKKMTAELQV-QLMNELLS-DNDALTK
AVGMATREKAELCRTVSRLE---KT--LKHHTQKG--------------CVLNR-QSKSS
LKQDGTDLQSSLRHSDPEWHSQ---------TTSGDTN-TCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TMSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALVH-PKSTR--HGH-----RTSQRQRSP---------
-----------SGPRASLPTRDTSSGPTKASRH-----------------------SPRS
AAAGSPGK-ERSTSTPSSRLERSLTASQDPEHSLTEYIHHLEMIQQRLGGLPPD--S-T-
QKSCHQKIKQ--------

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---------------MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTK--------
------RKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLET-------------
-------TTET-----------------------------EKVAVHSAAEYSELDDKMRQ
TRIAELEKRLLEKQQAV-----------GRLTVQMNELQEQLSQHRDSMQLQETTIQEQN
EVIRKLTSCLQQTR----KD-----------------------WDDLQEEASHVADQIHG
LQLQLHEVNV---MLKSKGSG-----KKEVL-EAQ-QQMSLFQSSLQEQNARLEMLHQRA
YDLEVQLESSQKIEELNAEIKDKV-EKQ------KKLEEERVEQLALVKKVHE-REHDRE
ISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEAL
RLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERC
LKEKED----LTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEM---------
---------------RLKYTCEELSKKHKAEIAELQKTLEMEL--------EKVKAELGL
LSLEKEQSEMK-CVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQ----KE
LEKLQVMHEEFKTRSQEEVKQLWSQLG-----STRANRQELS-ELKEQLMARASQVEEIE
HLKQKFEEQ---------QQQTK--SEHEAELEQLRIYFERKLRVTEENYREELTLLHQK
LQELKEYSVSGVDVSHNQAGNISSS----VIVFGEAVEK-ERKDFFLDQLNQQ-------
----LEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKG--DLLKMKMELSDKYIAEIE
EMKRKH-CLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSV-LEEEHKVK
LSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKE
AREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVRE
AQMNQLQDHQAA------------------------------------------------
---KIVELEKLVKEQQNNLKQLEDSLAVAQ-ATRKSQEQYDSDLQAAK--ELMAKEMEKA
ELCLQEECALKLMKAQNKFMEE----------------------HKALTQKFTAEQEILL
QELKKRHVDELELQSQ----QLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQL
EAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLH
EKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELAT--VHMEKLKIMAV---EAEEAH
KDDLKAALQN---QRSLLEEEKRLALDMLR---------------EEVVHMEEKHRKALQ
ELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEA
VKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAA
CQKEKETLS-AQLQEKAARIIQLEKRVE-SLNCEIQETNCELETLIERRDRENQEGGNLV
AMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSM-ASA--
-DSME---------SH-----SIVEEIGFAQYFK---AKEKSHLEKVDELLDETLTEHSQ
LSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEK
THEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAE
KAALEEALNLKEESERRLVVELENMRERFQELT------QEQAILGL-------------
----------------------LKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEE
QLHSNQDLTKQLME-TAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEE
QLKL-S-AKLQTSGEPREYG-----V-------ESLQAEVEEKVDDYNKLLLEKEQKHQE
IAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNN
LIQISALQ-SKLDEVRHGVPVEGTS-DQELKEQLQAEQESLERKEGEIASLLDHLEQHKD
ILTSKNEEILQLKLQLEV-QKNLSTSTINQLQIENAQLK-DLAKLHVKQNRDSDVGDSSA
LSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQE
RLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKG
LIDCQ---GDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILE
KKCQNLQESSRQ------------------------HF----------------------
------------------------AELNTLRLQ-YHALQEE-------------------
-------------------YSLLQTHISQRELEARIASSCVQELKDSMKEREV--SIL-G
KD------SQIQAMAHQREADEGELRYLTEQASDLETELKKRDAS---QAQDVHSPELEV
SRLDLHVQAMNQ--KEVSKQREIDE-LQGSTTKLKDQI--K-------------------
--I--Y-------------------------TKE-LEALHLERDELISQLELYKPKEQCD
KENANCL-------------------ELFCWGQRQGEVL--KEGME-ELESLETHVDQSF
ASPADNLE-------------------------------KVALFDFT-------------
----------------AHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTL--
--------DSPKI--------------------IVNAGCTEGTLKNFQDFIVD--VTSWD
SPEIMRKQDISMELPPAL---NLTPFSEAESTGLEM----AHSR-SSLQG-DNSVLLGFS
HLYENGS----------EEAAGRADVKSPVSS----ESIYSGADRDQDLKKTTLMSGT--
DNLTPSDLQDDVRSG---------ASAIDVMSN-GCDSSTRSNLEAKLKEQLQTSD----
---------HSDAN----FMAYLQYCGMFPDIMESVREK-EILSPQLKTVLKLVYEESHK
ILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSL-------------------
---------K------DYLSKVADRGDKEEQRQMV-------VE----------------
-------------------HLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTS
VEDHGSKQEHQLRRKVELLEYK-------------------LQQEKCIVSDLHSTLSEEQ
KRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKL------------
----------------CFELESKEKDLTA-------------TLQELEAE----------
--RLTETELRVLLEEQQ------------LQHKKAEDEK---------KKALE-DLQAAL
DLQTAQN--RKLSVSLEHEQII-NDNLRKELRIEY----------SRCEALLSQEHD---
KVLELQKNLDAER-NRSLEL------LNSLNHERILTEQLSVQAKEDASC--QRRELLLE
QAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQ-MCCEETQKEKEITNK
LRVMLDSL----------------------------------------------------
---------QSQKQEQNLELQHQRDEQRIKEMQEI---VAILGETERSPPSPSSQQGLLC
TSDKD---QNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVND
WYVSNDEAVASLLQTLKELKSDLLSPASQI------RSTDDSN-PVQELE----------
-------------RAAWQQE---RN-ILQNALKQA-----------------------ES
KLAKATAE-----TENKP-A-----------------MEAFNPKLQRLYRKYLRAESFRK
ALV-YQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAV
IAVSRL--KFLVKKWNKLNRKNAQAE-TVSQN--TGSNTASG----------ARTETLKQ
QQ-------LTAVHVSSPPTWDTGLCHRTS-SA-------------------------RS
VSCSSKSSHRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPG--QV-P
GPPCQRNMKK--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAK--------
------RKGSAVNASVQEES--PVTKE-DSALCG-GGD--ICKGTSCD-------DTPDG
AGGAFA----AQPEDCDGEKREDLEQLQQ----------------KQV---SDHPPEQR-
-GMFT-------------------------------------------------------
------------------------------------------------------------
------------------------------------------VSD----------HQPEQ
RGMF--------T--------IS-D--------HPGEQRG-----MF-TKECE-QECELA
ITDLESGREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAERA-LRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASRVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGAREDALLDSVE-------VGLS----CVGLEEKPE--KGRKDHVDELE---------
----PERHKESLPRFQAELEESHRHQLEALESPLCIQH---EGHVSDRCCVE------TS
ALGHEW---R---LEPS--EGHSQELPWVHLQGVQDGDLEADTEGAARVLG-LETEHKVQ
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKDDLEKVKHNLIEDHQKELNN
AKQKTELMKQEFRRKETDWKVLKEELQREAEEKLTSMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQDLTSDDAL---HCSQCGREPPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHAREL----R----LLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALL
AARVAEMQTKHAADLSALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLQ
KKDSLHQTILTQELEKLKRKHDRELQSVRDHLRTEVST--EL---AGTMA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GVHQGEFGSEKKTALHEKEETLRLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIQECRSELEVLQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAVTLRSRIGERVGLCLDDAG---A--
-GLAP---------SAAPALEETWS--DVAL------LELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLMEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESTAKAELALELHKTQGTLEGFKVE
TADLKEALAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSQGEATA
TDAEAREA------------ALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--AKPQPWGPRDSQ------QAPLDGEVELLRQKLREKLDEFNELALQKESADRQ
VLMQEEEI-------KRLEEMNINIRKKVAQLQEEVEKQKNVVKGLEQDKEVLKKQQMSS
LLLASTLQ-STLDAGRCPEPPSGSP-PEGPEVQLEVTQRALLRHESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLDM-QNSQTAVSLRELEEENTSLK---------------------
------------------------------------VIYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQTLQGELEAALEAKEALSRLLADQERRHSQALEALQ
QRLQGAEEAAELQLAEL-----------------ERNVALREAEVEDMASRIQEFEAALK
AKEAMIAERNLEIDTLNQRKAAHSAELEAVLLA-LARIRRALEQ--------QPLAAG--
AEPPELQWLRAQCARLSRQLQVLHQRFLRCQVELDRRHARRATAHTR----------VPG
AHPQLRMDGGAKTQVTGDVEA-------SHDAALE--P--VVPDPQ-------GDLQPV-
-LVTLKDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDGG
----------------------------KGKEKV-LEDCQLPKVDLVAQVKQLQEKLNHL
LYSMTFQNVDAADTKSPWPMAS-AHLLESSWS--DDS-----------------------
-CDGEEPDISPPIDTCDANTAMGGVTDVIKNQAIDACDANTTTGGVT-------------
--D-------VIKNWDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SVLGGSHHQSHTAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLGDRADTSLPQT-QGPGLLCSP
GVST---AALALQWAESPP-----------------------ADD-HHVQRTAVEKDVED
FITTSFDSQETLSSP---------PPGLEGKAD-RSEKSDGSGFGARLSPGSGGPE----
---------ARTAGPVT----PAPISGRFQPLPEAMKEK-EVHPKHVKALLQMVRDESHQ
ILALSEGLAPPS----GE------------PHPPRKEDEIQDSSLHGG-K----------
TQ---EVPTACPDWRGDLLQVVQEAFE--KEQEMQGVELQPRLSG-SDLGGHSSLLERLE
KIIREQGD----LQEKSLEHLRLLDRSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTS
AQARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQTVVRDLKSDLCESRQKNEQLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQ-KHCEALKREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPA
AAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEAMRQRLLSAARLLTSFTSQAVDRTVND
WTSSNEKAVMSLLHTLEELKSDLSRPTSS----QKKMAAELQF-QFVDVLLK-DNVSLTK
ALSTVTQEKLELSRAVSKLE---KM--LKHHLQKG--------------RSPSR-SERSA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFTRFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAPR--T-----GPRARR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GRRL
AAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPD--STS-
KKSCHQMIKQ--------

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------------MEAQQEQRRRKVEAGRAKLAHFRQRKTKGDGAHSEKKTAK--------
------RKGSAVDAAVQEES--PVAKD-DSEVRG-GGD--IYKSPSCD-------HTPGG
AGGAFA----AQLEDCDGEKREDLEQLHH----------------HSG---CDHHPGQRG
HGAITVSD----------------------------------------------------
---------------HHPEQ-HGAITVSDH-HPGQRG------AITIS--DHPGQH--GA
ITVSDHHPGQRGAITVSDHHPEQRGAITVSDHHPEQR--GA-------------------
---I--------T--------VS-D--------HHPEQ-C-----G-AITECE-QECELV
TADMESPREDEAGPQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELGLLREQH
ALEKEE----VALRCGREAAELKEKLQSEME-KSAQIIKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMKDLQNQFQKEL--------AEQKVELEK
IFQDKNQAEWA-LRNLESQHQAAIEKLREDLQSKHCRYLEDLELKFKENEKEKQ----LE
LENLQASYEDLKAQSQEEIRHLWSQLD-----SARTSRQELS-ELHEQLLACASHVEDLE
QLK----------------QA-E--VQHESELERLRIYFERKLRDAEKAYQ-DLTLLQQR
LQGAREDALLDSVE-------VSSS----CMDVEETLE--KEKKDHLDKPE---------
----PERHKESLPCFQVELEESHRPQLEALESPLCIQH---EGHVSDRRHVE------AA
ALGQAW---R---QEPS--EGHSQELPWVHLQ---DGAVEADTEVAARVLG-LETEHKVK
LSLLHTE------LKEEIELLKIENRNLY-EKLQHEIRLKEDLEKVKHSLVEDHQEELNN
AMQKIQLMKQEFRRKEVDWKVTREELQREAEEKLTLMLLELREKAESEKQSVVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTADEAP---RCSHCGREPPA-------AQDGELA
ALRVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
REAQEQHAREL----Q----LLQEKHQQRLLSVTAELEARHQAALGELTASLENKQGALL
AARVAELQTEHAADLSALENRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KKDSLHRTILTQELEKLKQKHDGELQSVRDGLRAEASP--EL------------EL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQAEFGSEKKATLPEKEETHRLQSAQPQPF
HQEEKESLS-LQLQKKNQQVQQLKDQVF-SLSHEIEECRAELEALQQRRERENQEGANLL
SMLRADADLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---T--
-GLAL---------SAAPALEETWS--DAAV------PELDRTLSECA------------
---EMSSVAEISSHVRESFLMSPESVRECEQPIRRIFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLQKALAGKEDSEHRLVLELESLRRQLQQAV------REQAALREECARLWSQGEAAA
ADAEAREA------------ALRKKAEDLVTEQSETRKQAEKDRSALLAQMKILELELEE
QLSQHLGCAKQAEA-VTALEQQVASLDKHLRSQRQFMDEQATEREHEREEFQQEIQRLEG
QLRQA--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKSDEFNELALQKESADRQ
VSMQEDEL-------ERLEEMNVNMRKRVAQLQEELENQKNIVKELEQDKETLKEQQMSS
LLLASTLQ-STLDTGRYPEPPSGSP-PQGPEAPLEVTQSALLQRESEVLDLKEQLEKIKG
DLVSKNEEIQHLNLKLDL-QNDQTAISLRELQEENVSLK---------------------
------------------------------------VTYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQQELSLMGPVLHEVGHSQAGSLQSEL----LCSQA-GG--
---------------------PGGQALQGKLEAALEAKEAVSRLLAEREHGHSQALQALQ
RRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALR
AKEVMIAERDLEIHALNQRKVAHSAELEAVLSA-LARLRRALEQ--------QPLTAL--
AEPPELQRLRAQCARLSRQLQVLHQRFLRCRVDPDKRQACGAAAHAG----------VPG
VHPQPRADG--------DVEA-------SHDAALE--P--AVPSPW-------DDPPPV-
-LVTLKDAPLCK------QEGMMSV-LSICQRQLQSEL--LLVKN-----EMRLSPEDGS
----------------------------KSQEEV-LADCQLPKVDLIAQVKQLQEKLSCL
LDSMTFQDVDRM--WEPWA-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------REAGPRKAPVRMLDLSSWS
SPEVLRKDW-TLEPH----------------LPSADTSPRDRADVSLLQA-QGPGLLCYP
SASA---AALTPKWAGSPP-----------------------A-D-LHVERTAVEKDVED
FIT-SCDPQETLSS----------SPGLEGKID-GSEKSDGSGFGARLSPGSGGLE----
---------AHTAGPVT----PAPISGGFQPPPEAMKEK-EVHPKHMKALLQMVRDESHQ
ILALSEGLMPP-----SE------------PHPAWKGNEVLDGSLRGG-K----------
TQFYFDLPTTCPDWSGEFLQVVQEAFE--KEQEMQGVELQPQLGG-SDPEGRSSLLERLE
KVIREQGD----LQEKSLEHLRLLDRSSLLSEIQALRAQLRMTRLQNQEKLQHLLMALTS
AEARGSQQEHQLRRQVELLTYKV-------------------EQEKSIAGDLQKTLREEE
EKANGLQKLLAAEQSAVRDLKSELFECRQESERLSGSLHEVQQEVLQLR-----------
-----------------SVLTSKENELKA-------------VRQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQNAKALE-ELRASL
ETQRAQS--SRLRVALKHEQVA-KDNVQKELCIEH----------SRCEALLAQERVQ--
-LSDLQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-RAQHTLLQKLREEKSRVVDLQAMLGK-----VRSQQQLEAEAR-KHSEELRREKEVSAT
LEATVEAPHTPTRELRCFLEREREKPAWLQAELEQLHPRSKEQEAPKAARRSTEAGQSAA
AAEQWREWQRDEEQLRELELQRQRDLHKIRQLQQM---VRDLESKDEAP-GGRLHPDSAR
----K-------ALSSD----VDHLREQQRELEAMRQRLLCAAGLLTSFASQATGRTIND
RTSANEKAVASLLHTLEELKSELSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVAKLE---KM--LKQHLQKG--------------CTPSR-PDRSA
WKPDEMVPESSLRRPDPGRLPP---------AASGEAS-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAEQR---ITSRPVTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGAVAQ-GRAPR--P-----GEAPAT-SPLT---------
-----------PRARESPPTRDVPLGHARDSAR-----------------------GHGL
AAAASPHSGGRATPPPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGAIAD--SIS-
KKSCHQKIKQ--------

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------------MEAQQEQRRRKVEAGRAKLAHFRQRKTKGDCAHSEKKTAK--------
------RKGSAVDAPVQEES--PVAKD-DSEVRG-GGD--VYKSPSCD-------RTPDG
TGGAFA----AQLEDCDGEKREDLEQLHH----------------HSGWWNIDHHPEQH-
-GVITVSD----------------------------------------------------
---------------HHPEQ-CGVVTVSDH-HPEQRE------VVTV-------------
---SDHHPEQRGVVRVSDHHPGQRGVITVSDH----------------------------
----------------------------------HLEQRG-----V-ITKECE-QECELA
IADMESWREDEAGPQQ--------------------------------SQAVHGLELEAL
RLSLSNMHAAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELDLLREQH
AREKEE----VALRCGQEAAELKEKLQSEME-KNAQIIKSLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMKDLQNQFQKEL--------AEQKVELEK
IFQDKKQAEWA-LRNLESQHQAAIEKLREDLQSEHCRYLEDLELKFKENEKEKQ----LE
LENLQASYEDLKAQSQEEIRHLWSQLG-----SARTSRQELS-GLHEQLLARASHVEDLE
QLK----------------QA-K--IQHESELEHLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGAREDALLDSVE-------VSSS----GMGFEETPE--TERKDHLDKRE---------
----PERHKESLLCVQVELEESHRHQLEALESALCIQH---KRHVSDRSHAE------AA
PLGQAW---R---QKPS--EGHSQELPWVHLQ---DGAVESDTEVAARDLG-LETEHKVK
LSLLHTE------LKEEIELLKIENRNLY-EKLQHEIRLKEDLEKVKHSLVEDHQKELNN
AMQKIQLMKQESKKKEVDWKVTREELQQEAEEKLTLMLLELREKAESEKQSMVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELMADEAL---RCSRCGREPPA-------AQDGELA
ALRVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
REAQEQHAREL----Q----LLQEKHQQRLLSVTAELEARHQAALAELTASLENKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KKDSLHRTILTQELEKLKEKHDRELQSLRDDLRAQTSP--EL---ARTVA---YQL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKATLPEKEETHRLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVF-SLSREIEECRAELEALQQRRERENQEGANLL
SMLKADADLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDTG---T--
-GLAL---------LAAPALEETWS--DAAL------PELDRTLSECA------------
---EMSSAAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEENAAKAELTLELHKTQGTLEGFKVE
TADLQKALAAKEDSEHRLVLELESLRQQLQQAE------QEQAALREECACLSSQGEAAA
ADAEARET------------ALRKEVEDLVTEQSETKKQAEKDRSALLAQMKILELELEE
QLSQHLGCAKQAEA-VTALEQQVASLDKHLRSQRQFMDEQAAEREHEREEFQQEIRRLEG
QLRQA--ARPQPWGTHDSQ------QAPLDGEVELLQQKLREKSDGFNELALQKESADRQ
VSMQEDEI-------KRLEEMNVHIRKKVAQLQEELENQKNIVKELEQDKEALKDQQMSS
LLLVSTLQ-STLDAGRYLQPPSGSP-PQGPEAPLEVTQSALLQRESEVLDLKEQLEKIEG
DLVSKNEEILHLNLKLNM-QNNQTAVSLRELQEENTSLK---------------------
------------------------------------VTYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQQELSLMGPELHEVSHSQAGSLQSEL----LCSQA-GG--
---------------------PVGQALQGRLEAALEAKDAMSRLLAEQEHRYSQALQALQ
RRLQGAEEAAERQLAEL-----------------ERSAALREAEAEGMASRIQEFEAALR
AKEVMIAERDLEIHALNQRKVAHSAELEAILSA-LAHLRRALEQ--------QPLTAL--
AEPPELQRLRAQCAHLGRQLQVLHQRFLRCWVELDKQQACGAAAHTG----------VPG
VHPQPCADG--------DVEA-------AHDAALE--P--AVPNPR-------GDLQPI-
-LVTLKDTPLCK------QEGMMSV-LSVCQRQLQAEL--LLVKN-----EMCLSLEDGG
----------------------------KSQEKV-PEDCQLPKGDLIAQVKRLQEKLSCL
LDSMTFQDVDAADMKSPRLVAS-AHLLESHWG--DDS-----------------------
-HDGEEPDRSAPVNVCDASTAT---------------------GELT-------------
--D-------VIKNQGSLIPD-EVPDSPIQEKSECQDGPRSSPT----------------
-----------------------------SLLGSLHLRSRAMEARPPKSPVRMLDLSSWS
SPEVLRKDW-TLEPQPS---LPLTPHSGALSLCSADTSPRDRADASLLQA-QGPGLLCYP
SVSA---AALAPKWAGSPP-----------------------D-D-LHVERVAVEKDVED
FIT-SFDPQETLSSP---------PPGLKGKTD-GSEKSDGSGFGAKLSPGSGGLE----
---------AHTAGPVT----PAPISGRFQPLPEAMKEK-EVHPKHMKALLQMVRDESHQ
ILALSEGLMPP-----SE------------PHPAWKGNEVPDGLL---------------
----HNLPTTFPDWSGEFLQVVQEAFE--KEQEMQGVELH-------------SLLERLE
KVIREQGD----LQEKSLEHLHLLDRSSLLSEIQALRAQLRMTHLQNQEKLQHLHMALTS
AEACGSQQEHQLRRQVELLTYKV-------------------EQEKSIAGDLQKTLREEE
EKAHGLQKLLAAEQSAVRDLKSELCGCRQESERLSGSLHEVQQEVLQLR-----------
-----------------SVLSSKENELKA-------------VRQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREDQNAKALE-ELRASL
ETQRAQS--SRLCVALKHEQVA-KDNLQKELRIEH----------SRCEALLAQERTQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTERLSQRTQEACAQ--QDT-----
-QSQHALLRKLREEKSRVVDLQAMLEKLQQQAVRSQQQLEAEAQ-KHYEELRREKEVSAT
LKATVEALHTPERELRCFLEREREKPAWLQAELEQSHPRSKEQEARQAARRSAEAGQSPG
AMEQWKKQQRDKEKLRELELQRQRDLHKIKQLQQM---VRDLESKDGAP-GGRLHPDSAR
----G-------AASSD----VDHLREQQRELEAMRQRLLCAVGLLTSFTSQAVGRTIND
WTSSNEKAVASLLHTLDELKSELSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVAKLE---KM--LKHHLQKG--------------CTPSR-PDRSA
WKPDETVPESSLRRPDPGWLPP---------AASGEAN-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---IMSRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GRAPR--P-----GPRTRRPQQSP---------
-----------PRTRESPPTRDVPLGHARDPAR-----------------------GHGL
AGAASPHSGGRATPSPNSRLERSLTTSQDPEHSLTEYIHHLEVIQQRLSGAIAD--SIS-
KKSCHQKIKQ--------

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-----------MEEDEQEQRRRKVEAGRAKLASFRQRKTKGDGPNSKKKTAK--------
------RKGPAVNAPVQEEG--PVATP-DSELPD-GGA--ACGSRSCS-------NALEG
ARGAFA----AQEQED-----------------CELDET---------------------
------------------------------------------------------------
-----------------------------------------------------DL-----
------------------------------------------------------------
------------------------QEQQQ-----ELQP-QPPQ-----------------
-------------------------------------------------TTAHNLELEAL
RLSLNNMHTAQLELTQANLQKEKETALKELREMLNGRRAQELALLQSRQQCELELMREQH
AREKEA----VVLRCGQETAELKEKLRSEME-KNVQMIETLKQDWESEREL---------
---------------CLENLRKELSAKHQSEMESLQNQFQKEL--------SQQRAELEK
IFQAKQEAEVS-LKNLETQHQAAVKKLQEDLQSEHCQYLQDLESKFREKEKEKE----LE
LETLQTSYEDLKAQSQEEIRCLWSQLE-----SVKTNREELN-GSWEPLLARDSHLEELE
HLRSDFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLRDAEKTYQEDLTLFQQR
LQEARED-SLESAE-------ISSS----CVFPEETSG--RETKEQPDPLDR--------
------------------------------------------------------------
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---------------------------------------QLEQPQVRHSLVEDHQVKLKT
AEEKIQLLKQEFQKKEAEWEHSHEDLKREAEERLTSMFLELREKAESEKQSIVNRFELRE
SSMRHLQDQQAA------------------------------------------------
---QILDLEKSLMEQQGRLRQLEQELTRDEVL---PCSHCGQEPLV------AQDEEHVM
LLREKEDCALQLMMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDAQEKHIHEL----Q----LLQQGHQQQLQALRMELESKHHSELAQQLASLESKQQVLL
ETHVAELQVKHSAEIRALEMRHLSNLDALESCYLADVQTIRDEHRRALELLRAELEEQLQ
KKDSSHKEILTRELEKLKLKHEEELQSAKDSLRMEMHA--RHTEKVKGLAT---DVQAPQ
QEELAMTLHN---QRYPLEKDGSAALGS---------------VGAEVSL----H-----
------------------------------------------------------------
----------------------------QAVPQELR-----------DTHTVEMQKPQ--
----AELAKPQELQASQEQAAQVS-QVF-SLSREIEECRAELERLQQRRERENQEGATLI
CMLRADADLARSEGKVLRDALRRLLDLFGETLKAAVTLKSRISERAGLLLDHADAAET--
-SDAR---------LAAAALGDMWSD--EGL------LEVDRTLPEGA------------
---ETSSVSEISSHVCESFFMSPENTLECEQPIRKVYQSLSTAVDGLLEMALDSSKQLEE
ARQLHCCVEKEFRHRNEEIAQAVQKQQELLERLRQESAAKDGLALELHTAEGLLEGFKVE
KAELQEALGKKEESEQQLILELENLRKQLQQAA------QELVTLREENSALWSQKETFT
NEAKERE------------AALRKEVESLTRDQWEARKQSEKDRATLLSQMRVLESELED
QLVQQRGCAQLTEE-VATLKQQLAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--ARPRPPGPHDSQ------VG---QPVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEQEI-------KRLEETNVNIQRQMAQLQEELEKQKKNMEEL-KDKEVLKQEHASD
LLLPPVPQ-CRLDEAGCPILPQGGS-SRDPESPAGVTERTLLQHEN--------------
------------------------------------------------------------
-----------------------------------EGVHRRNSEIEELKAIIENLQENQE
QLQKDKAEEIEQLHEVIEKLQSELTLMGPKVHELSDHQASNLH----NELSCLHAEGQR-
-----------------------GQALRNELEAAQAAKEVFGQLLADQAHGHSQALEALQ
QRLQDAEEAAAIRLAEL-----------------ERCVALREAELEDMASRIQEFEATLK
AKEAIIVQRDLEIDTMNKWKVSHSLELENILLA-LTQFCHALEQ--------QTFATP--
DEPPELQQLRRQCAGLSHQLQVLHRRFLRCQVELDQQQAQVASVGC--------------
----SYP------CA------D--------------------------------------
--------AQLE------QDDVSIG-LAL---------------------------APHS
S---AP----------------------QAKEKQ-LEDGQLGSANLIVQMKQLQEKLNHL
VHSMASRDTSLENPKLHQ-----PNLSENGLS--NNC-----------------------
-HNDEGSNVSPPVDVFNTARTT---------------------WDVI-------------
--D-------AIKNQDLLAQI-EMPSFPTQETLTPQGGPLSSQI----------------
-----------------------------SVHSDS--LNTEE-AEPQKDPVRALDLSSWS
SPEVLRKDS-SLEPQHS---LPLTPRTGPVSLHSVDTSSQDWTDS-LLLA-DASGLLCYP
GKSA---TGQAPLWGLA------------------------PSAENHHVERPATEKDVED
FIVTSFDSQELLTSS----------HESA-RSD-GSGKNHGPSSALMLTLGSEGAE----
---------TPTTDLAAA--AALPFSRRFIQSPGAMKEK-EIHAKHMKALLQLVFDESHQ
ILALSESQDLPNSLSKGE------------PHDPLDGLPRDRQALLEVTT----------
SRGEKESSEAQLPWNEELLRAIQEVFA--REQE--NAELQPRAYD-LGLGDYNALFKKLE
RVVQEQGG----LQ-KVQGELCLPDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIAHDLQKTLNQEQ
EKASDVRKLLMVEQSAVQDLKSELHACKQENTRLLESLDQVQQEVLRLRYGHVSH-----
-----SGTS--SASAGQAMLDGKENELKV-------------VLEELECE----------
--RGKERALQAQQEEQQL---------------------RHLQREGQSSRALE-ELKMSL
EKQRAQN--NQLCVALKHERAA-KDNLQKELQIES----------SRCEALLAQEKGQ--
-LCELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNAQEACAR--QET-----
-QVQHALLRKLKAEKARALELETMLEKVQKQAA---------------------------
---------------------------------------------HIQQQLESQAQ----
----ERCVELRKEKERELELQRQRDEHKIEQLQEL---VRELRWKEKVAEGDGPCRSCPR
----LG---------SL---ELDHVQEQQQELENIRQQLLCAAGLLTSFANRTVDRTIKD
WTSSNEKAVSSLMHTLEELKSELSIPTSS----KKKMAAELQV-QLVNELLR-DNDALSK
AVSAATREKAELCRTISRLE---KT--LKHHTQKG--------------CLLSR-QSKSS
WKQDGTVLQSSLRHSDPEWHTS---------TTSVETN-TCNTKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKVDKKI--TTSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALLH-GRSTR--QGH-----RMSRRQHSP---------
-----------SENRASLPTREVSSGHIKDSRH-----------------------SPRS
SAAISLSKVERSPSSPNSRLERSLTASQDPEHSLTEYIHHLEMIQQRLGGLPPD--S-T-
QKSCHQKSKQ--------

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------------MEDEQEQRRRKVEAGRAKLAHFRQRKTKGDCAHSKKKTAK--------
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IGAAAA----A-------------------------------------------------
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RLSLSHAHAAQLERTQAALQREKEAALSELRAALLGRLAQERALLQSGAQRELELVREQH
GRETGTLSF-----YVSLAAELKEKLRSEME-KNVQMIETLKQDWESERDV---------
---------------CLENLRRELLEKHQLELENLQNQFQKEL--------AEQRAELEK
IFQAPSQAECS-PQTPEAQHEAAPRQPHADLPPERCLCLGDVELKFKEKEKENQ----LE
LENLRASYEELQARSQEEIRRLGAQLE-----SARSSRQELS-GEELHLLARASHLEELE
HLKRDFELQ---------QQQER--TKHESELEELRVYFEEKLREAERGHQEDLALLEQR
LQEGKEGFRPQPVE-------TRVL----SGCLCPLSK--PGAREGLG------------
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TEQKIELLKRDLGDREAAWQVTCEELGRAAEERLSRRLLELREQAESEKRSLTNRFELRE
AEMRQLQDRQAA------------------------------------------------
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TLHLQEPSALQPKPAQSRLLGE----------------------CRAVTARLAAEQDAVL
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EARAAELQAEHAAAVGALETSHASHLDSLAARHLSEVQALQGRHRRALQLLRAELEEQLR
E-DASPREVLTRVFKKLKLERDEEPPCAGDGPELPGACQVRCFPGLGSPVP---------
------------------------------------------------------------
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------------------------------AGGEFE------------------------
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AMLRADVSLSLGERRALQDALRRLLGLFGETLKAAVALKSRISEHVGLCLEDESPLDGQP
GAPTP---------PA----GALTPGRMSPP------PELDGTSPDGA------------
---EASSVAEISSHICESFFMSPESTLECEQPVRRVFQSLGLAVDGLLEMVLDSSRQLEE
ARQIHSRFEEEFSCKKEEMAQVVGKQQELLERLDAEHEAKARLELQLHKAEGIIEGFKEE
KASLQEALGQKEASEQGLVVELEGLRQQLQRAA------RQQAELQEANSALWSQKEALA
AAAGDRE------------AALRRDVESLTQEQAEARKQAEKDRSVLLSQMRALEADLEE
QLSRQQACAQQAAE-LCALRQQLEALDQHLRRQRQFMDEQAVEREHEREDFQQEIQRLEE
QLRQA--ARPWPRGPRDSD------RAQLDEEVELLEERLREKSDGLNELIVKKELADRQ
VLTQEEEI-------KRLEEANASSRRELAQLQGELERLRKALRDLEQV----ILSCRGN
LLLVSTLQ-SKVDEGKCPVPPVGGS-SEGPEVQLEAVQRVLLQRED--------------
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-----------------------------------EAAHTRSPEIEELRSVIETLRQNQE
RLQRERAEETEQLHEVIEKLQRELSLAEPAGHEVSDGGAGNLR----SELLGLGAEGAEA
R----------------AA-------LEGELHAALEAKEALSRQLAEQERGHGRALAALQ
QRLRAAEEAAARQLREL-----------------QPSAALLEAEVQGLASQIRAFEAALA
AKGEELAAREAEVAALTAQRSAHASELEALLSA-VARFRRALER--------QPL-----
--PPELQRLRAQCVRLGRQLQALTQCFLRCQKELDEQPARGPACPL--------------
-----------------AGRDV-GSRQLAK----A--PHGQA------------------
------------------------------------------------------------
S---SP----------------------QDKEKL-LEDCHLRKADLITQVKQLQEKLNHL
VCSMSFQKVEMEDFKFQQTLSG-------------SS-----------------------
-SSSEEANGSPPVSVCNDNGTT---------------------WDLT-------------
--D-------VTGNQDALIKN-KMPDDPMAEPVALQDGSGSLQE----------------
-----------------------------SLHGCSHDLANTEGPEPVKNMLRTMDLSSWS
SPEVARKDS-TLEPLPS---LPLTPCSDALSQRSLDTSLWDGPSTWLLQA-DQSGLLCYP
DESA---AGMAPRRAASPL-----------------AADRAPSADR--------------
------------------------------------------------------------
------------------------------------------PAQRVAALLQMVCDESHH
ILALSECHGPSSILSRGE------------PRGPLEAA-----------------STPVP
RKGEKEPSDVALDWRREFLQVVQEAFE--KEREVLKA----RLRG-SDPGGYSSVLERLE
RVVQGQGD----LQERSLEHLRLSDRSSLLSEIQALRAQLRLTHLQNQEKLQQLCAALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKRIASDLQRTLSEEQ
EKASAAQKLLAVERGSVSALRAELCECRADNERLLRSLNDVQKEVLQLR-----------
-----------------SVLDSKEEALQA-------------ALQQLESQ----------
--RGKERALQGRLEEERL---------------------QHLQREGQSAKTVE-ELRASL
EKQQAQS--NQLCVALKHEQTA-KDNLRKELQIEA----------SRCEALLAQERSH--
-LSELQRSLEAEQ-GRSREL------AEALHHERRLTERLSRRTQEK-------------
-QVHEALLQKLKGQEARVLELEA--------------------A-LQ-TALQR-------
-------------------------------------------------ALEAEAR----
----PCREEVKREQERELALQHQRDEHKIRQLRARELRARELQAREAARPCP--------
-------------EPEP---EPESLQEQQQGLETARQQLLCAAGLLTSFINQTVDRTLSD
WTSSNEKAVASLLHTLETLKSDLGSSGSC----HRKTAAALQA-RLVDVLLS-DNESLRR
ALSTVTREKAELCRALSQLE---RSPRASRALQ---------------------------
--------------------------------------ESCTRRMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSQADKKA--PASRPLARFRTAVRVV
VAVLRL--RFLVKKWQQVDGRGALAP-GRAPR--PGT-----LLPRRQRSP---------
-----------PDALESPPTRDVSSSHARDPVR---------------------KASLC-
-------RRDRSSPAPNPRSERSLSASQDPERSLTEYIHHLEMIQQRLGAAPPD--STS-
KKSCQ-KIKQ--------

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-----------------------------------QRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------DTPDG
AGRAFA----VQLENQDREKREDLEQLQQ----------------KQV---SDHAPE---
------------------------------------------------------------
-------------------Q-RGIFTVSDH-HPEQRG------VFTV-SDHHPEQR--EI
FTVSDPHQEQREIFTVSDPHQEQRGIFTVSDP-HPEQRGVFTVSD----------HHPEQ
REII--------T--------KN-N--------PSP---------------QE-EECELT
IADLQSSREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAMEKFREDLQSEHCRRLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KGRKAHVGELS---------
----PERHKESLPCFQAELEESRGHLLEAPESPLCIQH---EGHVSDRCCAE------TS
ASGQGW---H---LEPS--EGHSQELPWVHLQGVQDGALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKAKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVTKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILNLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKLSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLQ
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLQTAASR--EL---TGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGIEKKAALHEKEETLRLQSAQAQPF
QQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQVRP
RLPGSRGEEEA--FLN---------------QILEEG--------ICVSHKGTLEGFKVE
TADLKEALAGKEDSEHRLVLELESLRRQLQQAA------QEQAVLREECTRLWSRGEATA
TDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQVEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNISIRKKVAELQEEVEKQKNIVKELAQDKEFLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSALLQREGEVLDLKEQLEKMKG
DLESKNEEILHLNLKLV-MQNSQTAVRLGELQEENMSSK---------------------
------------------------------------VVYTRSSEIEELKATVENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVGDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSQLLADRERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREA-----------------
------------------------------------------------------------
------------------------------------------------------------
-----------EAQVPGDMEA-------SHDGAME--P--VVPDPQ-------GDLQPV-
-LMTLEDTPLCK------QEGVMSV-LTICQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSLWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPIDACDASTAT---------------------GGVT-------------
--D-------VIKNRDSLIPG-EMPDSPIPEKSECQDRSLSSPT----------------
-----------------------------SMLGSSRHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPQPS---LPVTPHSGALSLCSADTSLRDRADTSLPQT-QGPGLLCPP
AVSA---AALALQWAESPP-----------------------ADD-HRVQRMAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGARLSPGSGGPE----
---------APTAGPVT----PAAISGRFRPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPRRKGDEVQEGLFCGG-K----------
TQFYFDVPTVCPDWRGELLQVVQEAFG--KEQEIQGVELQPRLSG-SDLGGHSSLLERLE
KVISEQGD----LQEKSLEQLRLPDRSSLLSEIQALRAQLRMAHLQNQEKLQHLRTALTS
AEARGRQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQENERLSRSLCEVQQEVLQLR-----------
-----------------SMLSNKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRGSL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDFAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-QHCEALRREKEVSAT
LKSTVDAPHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKATRRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIRQLQQT---VRDLESKDEVP-GSRLHLGSAC
----R-------AAGSD----ADHLREQQRELEAMRQRLLCAAGLLTSFTSQAVDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-LERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALAQ-GKVLR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAAAPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEAIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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----------MLKQAESQLAKANAEIENKPVAETSNPK------LQRLYQKYIRAESFRK
ALV-YQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSRSHSRPFTKFRCAVRAV
IAISRL--KFLVKKWNRVGRKSTQ-GESISHS----------------------------
--------------I---------------------------------------------
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------------------

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----------QLA-------------------DFRQRKAKGQGSNPQKKT----------
----QKRKSSSIH-----SH--DISQA-ESSIEA-AER--SPH--E--------------
--------------LEFTV---QN------------------------------------
------------------------------------------------------------
------------------------------------------------------------
I--Q-K---S-S------------------L-N-L-S-D-Y-H-G------------M-S
-D-V-E----------------E-G-D-----H------------------------MNH
--EVFDLYEEDGTEPE----------------------------I---PQSEHHMEMEAL
RLSLTNMHTAHLELCQANLQREKENALVQLREHLNDKRSQEVAILQGRHQFEVEKLKSQH
LDAMEN----LVVQHSQKLEMLQKEIMQLKEAQ-SQEIFHLQEQYEKKID---G-LKEEY
SQ-------------ELVEQKKKLEEMHQQDLADIKNTILNEMSLQHEEDMENLKMQLHN
ER---AQCEEL-TVQSQNEVSIL----QSELQKLK-EEMRKLLED-RAVEKESK---AGH
TRFHKQEGGYYDTRSSVEVQLLWSQLD-----GNRASRQELI-ELKEQLLARSAQVEEIG
RLKQDFEQQ---------RLQIK--VEHEKEMDELRIYFEQKSRMTEESYREELEMLLQR
LREIKDEDREELTQ-------QSSS----ILALDVPTE--NEQSHLLQQLTDE-------
----LLQHK-------VRHEVKQK-HEVELSN----------------------------
--VVSK-LQQLPKE----------Q--------QHKTELNNC-----------------M
SEL-QQE------HEEV-----IKNRVSE-LQQQHEMEL-------------------NN
RA----------------------------------------------------------
---SEMQQQH--------------------------------------------------
----KTELTNRMSELQQEHEKVIKNCVSELQQ-Q-HEMELNNRVSELQ-Q-LHEEVLKNR
VSELQQQHEMELN---NRVSGLQQLHEEVLKNRVSELQQQHEIELNNHVSDLQREHKEEL
KNLQRQHEEELDHRVS----ELQQI---------------HKEELSNRVSELLQGYKEEL
SKNVSDLQSEHKTQIEQLETTHMTNMDTLESSYLAEIHKIREEHSQALSDLEMCLADRLQ
EKEREMLEKLANAEMHWRDQHQQELHLLRELLGKELAA--VHMDKFQAMSR---ELEAAH
LEEMNEKLDH---QRHVLEQEKIHAFDALQ---------------EELQKIEQQHQIALQ
ELREFHDAEVKKRSLEE-------------------------------------------
------------------------------------------------------------
-----TGKLQLEIRKLKEEIQKLEEKIL-SLTKKMEKSHSQLEELVQRRERENQEGDNLV
AMLQADVSTAQQEKAKLQESCQQLLKLFSDVLKSTLSTEDLICKKIGLCLDSSLPHQ---
-ENV----------DRS----QTWGTFSLLKCGW---DEKNRVSPDC-------ETMTEQ
SLMSSDEGYEVSEYLCDSMLGSLEVGLENEEKILLMSQRLRTAVEQLLEMVAGSTTQLEL
AHEMQQKIQEEFRSSNLEMAQIVIQSQEMKKQLALEIEAKNQLQVELHKAQGLIEGYAAE
KETLEKTLSGKENAERLLVVELEKSREQLKVLC------QEPSLLGEEKEVLLKLQEVLS
GS------------VKNVEAELLKETERLAQEKLELHCQAKKDRSNLLSQMKVLEMELEE
QMSRNQELLRKTND-MSDLQQQIQSLEKQLKNQRHFMDEQAVEREHERDEFQQEIQKLEE
QLKLS--LKNLGD--SRA------YGV-STIEIENLEAQVKEKSDDCNLLLQGRDHLEQQ
ITERNEEI-------DKMLIR---------------------IQELEQAAL---------
---INADAAKKCT-------------------QLEEELQKLHKAQKE-------ILQDKD
ALQKQQYN---------------NALQISALQ---SKLDEARHKVPLAGES---------
-------------ENLLLKEQLQAER-EALLIKEKEPAHSQSSEVDELRSLVEHLRSDLE
RLRKDKEEEVEQLHEVIEKLQQELAQLGPNRHEVSDSQEDVQNL----EEE---------
------------------------------LIMYKGEVESLQQSLEESQAQHLAEIEVLD
QNLHNLQESTRQKVQELNSLQLQQASLQEEHELLRTVLSQRDSEVAILSSQVHKMQDSLR
ENKAFLTEKDLLIQTLQEQRAADVAALEEQLAQKCVSHELAVS-ELQELHTNSEA--L--
KEQEEKHKE---------------------------------------------------
------------EID----------------HLNQ--LLKTWEGKA-------KALTEEI
QTMKLQETEKNQLISRCESDQVLVRLGYLQYEQLSTAKEMLIGKETELHNTHDLLSSMKS
ELE-----------------------------EL-RTECELRETKAQQAIQQF-------
------KNLNQ-----HYPKVT-IC--QAYLS--KGKPPP--------------------
------------KGVLAIVQTE---------------------WIRY-------------
--S-------V---------G----VQKLQKTLESQEVTIASMSEELQK-----------
--------QNVEGRYNI---------------AS----DLRAYTKPRSFTESLTDLSDWD
SPDMVRKQE-EHMHSMRV-FTPFSELSIAYS-TDRDPIPSKSS--EYQKQTIQYDLLGSR
---------TPSLSGSNFS-----------------AQRTSPVSYHQLMEETRTWQLCKK
MLLGSFSMMDVFLASSHCCFFL----LMPRRRP-GHNQKSFLVKGPYSIITIIFYNEGYE
TSLKPEMRQGSLAGLKMDYLTKRG--------TSKNLQD-VWEKKTIQSMLQMIHEESCK
ILALSQRPVDQ-----IPSDPTVADTWLQDKQTLQDAMEKLSKALTE-AA----------
LKQEKDSSDVALDWRKELLQNVQSLLE--SEREYLRLELQSCLGN-HGSMDAGSMSERLE
HLLKEQEE----QKHLVMAHLLASDRSSLLSEIQDLRSQLRMAHLQNQEKLQQLQEALTN
TEEKGSIRDHQLRRQVELLEYKL-------------------QQEASIVADLNASLSREK
ERASEQHKLLLVEQGSVNQLRTQQEEWQLEQEKLVKTQKELQMDISTLR-----------
-----------------EQLESKAQALSV-------------YIEKLHTH----------
--QELES--KR-LEEEKI---------------------LQQQSQEHYEKTLQ-ELSKSL
EELQVQN--NNLSAALQHEQTC-CSNIKKDLQIEQ----------SRFEALLALEQNK--
-LSETQQELAKER-QQSQKL------SSTLTLERNMLDQLRQQHSTELSR--KDQEKLQE
HNTVLTLKSQLEEERSRAKDLAAMMEKTQQQAIHAKRQLEAEQEEERCWMKQKEKD----
------------------------------------------------------------
-------------RKKSLQQQHERDQHRIQELQHM---LAELEEQERAIASRKLQFQKES
FS-------PAKIFS-----DIS--TVYSKGLEKVWQQLFQMVLQVKEWVNKNNERKL-S
SHPDDEAVISMLN-TLSELKTELKLQTCSPV--SLLPSLQPLG--LMDVLQS-ENEELTK
SVTALTKDK--MELKS------QLA--Q-------LKRLQQPSEKQCCYFLLNQ-AERAA
WHRERRHLQIALKEAESELAKMTLE--NHPV-----PD-VPISKMQRLHRKYLRAESFRK
ALV-YQKKYLLLLLGGFQACEKATLSLIARMGVYPSPSDLQIPITQKPALTKFRSAVRAV
IAISRL--KFLVRKWHKINKKAGV-EDPVVQI--SA-----AFKQE-QNIG---------
-----------GVLLNSPPTKDVPLSSLRPSPISTSVQSPKTTHWIHNRISHSPA-----
-----------------LTPEQPQNTSHDPERSISEYIRHLELVQQRLGGLQNG--TSP-
ELSRNKYVRK--------

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-----------MDGDEQEQRRKKVEAGRAKLAHFRQRKTKSDCTHSKKKTSK--------
------RKGSAVDAPVPEED--PVAAQ-DGRPLG-ARD--LGRSTPCS-------RTTDG
ARGALA----AQE-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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---------------------------------------------------------EEQ
DCELASRSEDEAAQQQ----------------------------Q---PQTAPSLELEAL
RLSLSNMHTVQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRLQCELELVREQH
AREKEA----MALRCGQETAELKEKLRSEME-KSVQMVETLKQDWESEKEL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AGQRAELEK
IFQAKNQAEVS-LKNLEAQHQAAIKQLREDLQVERCQCLEDLESRFREREKEKQ----LE
LENLQASYEALKAQSQEEVRRLWSQLE-----SVRTNREELN-GPLEPLLTRASCLEELE
HLRQGFAQQ---------QQRDR--SQHESELEQLRVYFEKKLRDAEKTYQEDLTLFQQR
LQEAKEEPPLGSGE-------VSSS----CTFLEEMSY--GKRKEHSDQLDLR-------
----LERQK----------------MGPAWDSSLHVQH----EDQLDRCL----------
--LGPE-VLELEPLQAVPSDQHSQETEQVHHQCVQDVTLKEDMQVAARVLA-LEAEHKVR
LSLLQTE------LKEQIELLKIENRNLQ-EKLQHETRLKEDLESVKRSLLEDHQEELNK
AEQKVQLLKQEFRNKEVEWELLREDLRREAEENLASMCRELKEKAESEKQSAVSRFERRE
AGMRHLQDQQAA------------------------------------------------
---QILALEKSLAEQQGRLRQLEQALAGDEAL---PCSGCGQDPPVAS-DG-----QRGT
LLQGKEECALQLMQARNRFLEE----------------------RKEIMEKFAADQDAFL
RDAQEKHAHEL----Q----LLQQGHQQQLLTLRTELESRHQVELAELAATLEREQQVLL
EARVAELQMKHTAEISALETRHSSSLDALESCYMSGVQAIQDQHRQALELLRAELEEQLQ
KKDSSHQAVLTQELEKLKLKHEKELQSAKDSLRMEMRA--KHTEQLKALAV---ELQGAH
QAALESEQEP---A---ACEQESEQ--------------------ARSLCQRRSK-----
------------------------------------------------------------
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---------PLQP-QEDSQVQQLKGQVL-SLTQEVEECQAELERLRQRRERENQEGATLV
SMLRADVDLSQNERGVLRDALRRLLGVFGETLKAAVALKSRIDERLGLFLDHAE---A--
-GQAP---------SAAPPLEEVWSD-AAL-------LELDRALPEGA------------
---EMSSVAEISSHVCESFFMSPESTLECEQPIRRVYQSLGMAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFNHKNEETAQVLQKHQELLECLKEQRAARAELALELHRAEGLLEGLKVE
KADLQEALGRKEESEQQLVLELESLGRQLDQAA------QEKAALQEEHSILWSQREAWA
AEAETR------------EAALKKEVESLTREQVEAREQAEKDRAALLSQVRLLELELEE
QLSQHRGCARQAEEEAVALKQQLAALDKQLRSQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--ARLRPLGPFDSQGRQCA---QLDEEIELLQEKLREKSDGFNELVIKKELADRQ
VLIQEEEI-------KHLEETNANTKRQVAQLQEELEKQKKMVKKL-QEEEAVKEQQRSD
VILVPLPQ-SRTPEGRCPMPPRASP-LEGPEVLSEALQRALLQHESQVLDLKEQLEKMKD
DLVGKNEEILHLKLKLDV-QSDPAATSTRGLDEE--------------------------
-------------------------------SAGIQGEYSRSSEVEELKAIIENLQENQE
RLQKDKAEEIEQLHEVIEKLQSELSLMGPVVHELSDSQVGSLHS----ELLCSQAQGPGG
Q------------------------VLQAELEAARAAKEALGQLLADQARGHSEALEALQ
QRLKAAEEAAARQLAEL-----------------GHSVALREAEVQGMASRIQELEALLK
AREATLVQRDSEIGALNRSRAAHSAELEAVLLA-LARFRCTLEQ--------QPRAAP--
EEPPELQRLRVQCVRLSRQLQALSHRFLRCQAELGKQQACVDAE----------------
AV--------CDDRLEQGS------------------GGPHGQGPQ-------DDLQPAK
VLVTLKDTGFHK------PESAMSV-LTVCQRQLEAEL--LLVKE-----GMCLSPEDVG
RVPAGM----------------------QGKNKR-LEDCQLQKFNLIAQVKQLQKKLNRL
VHSMAFQDMDMGGSEPQQPLAV-ASLSENSSS--ESS-----------------------
-CSGEAADALPPVDAFALPMTP---------------------WGLI-------------
--G-------NTKGRDSLVRM-EMPDTEGQ------DEPLSSRT----------------
-----------------------------SDPSE---SCHAKEAEPEKDPLGVLDLSSWS
SPEVLRKDA-TLDPQPSF---PPTPCSAALSLPSVMASPQPGA-DSLLQA-DMSELHCYP
GGS---AAGPALQWA---------------------GALPADHHHHHPMESTAAEKDVED
FIATASNSQDTRRSS---------PLGLAGDCD-GSEHSGSLGCGMMLSPELGRPE----
---------VPTAGPATPAL----VSRGSPQPPGVMKEK-EVHPLHMKALLQMVCDESHQ
ILALSESRGLPSTLSKGE------------PWASLDYFSSEGQGLLEGAP----------
ERGEKESSDMHLDWRGRFLQAMQEALE--REREKLKAELQSRPSG-PDPVDYSFLFERLE
KVVREQGD----LQEKAQKHQRLQDRSSLLSEVQALRAQLRLTHLQNQEKLQQLCAALTS
AEARGSQREHQLRRQVELLAYKV-------------------EQEKCIASDLQRTLSKEQ
ETASDVRRLLALEQSAAQDLKS-------ENARLLQSLDEVQRESLQLR-----------
-----------------SLLDGKESDLKA-------------ALEELERE----------
--RGKERVLQAQQEEQQL---------------------QHLQREGQSAKALE-ELKISL
EKQHAQN--NQLCIALKHERMA-KDNLQQELQIEH----------SRCEALLAQERSQ--
-LSQLQESLEAER-SRSREL------SEALQHERVLTEQLSRSTQEKPM-----------
---QHTLLRKLKEEKARVQELQAVLARVQQQALHTQQQLEAQAQ-EHRVQLQKQ------
------------------------------------------------------------
-------------QERELQLQRQRDAHKMEQLQQV---VRGLRAEEEAAAPQGDGPRPGS
----------------L---ELDLLQGQRQELERIRQQLLCAAGLLASFVSRTVDRTIHD
WTVSNEKAVSSLVQTLQGLKSELSTPTSSQK--K--TAAELQV-QLVDLLLQ-DNNALTS
ALSTAAREEAELRRVVSRLE---RT--LKHHAQKGC--------------VLSR-SGRSA
WKHDRTV----PRYSDPGRPTL---------DASEEAN-ISSVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKG--ASSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGVP-PQGRAPR--PG-----PRVPQQQLSP---------
-----------PETRLTPPTQDEPSGLARDTA-----------------------QGSGP
AAAAFPSRKERSAPSPNSRSERSLAASQDSEHSLTEYIHHLEMIQQRLVGVQPD--STS-
KKSCRQKTKQ--------

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------------------RRRRKVEAGRAKLAHFRRRKTKGDGADSKKKTAE--------
------RKGSAFVAPIQEES--PLASP-DGGLLG-AGV--VCQSAAHS-------DTPDG
ARGSFS----QEQDHE-----------------LVRGPK---------------------
------------------------------------------------------------
-----------------------------------------------------DG-----
------------------------------------------------------------
------------------------AGQQQ-------QQ-QQSL-----------------
-------------------------------------------------QTVPTLELEAL
RLSLNNMHTAQLELTQANLQKEKETALSELREMLNGRRAQELALLQNRQQCELELVREQH
AREKEA----VLLRCGQETAELKEKLQSEME-KNVQMMESLKQDWESERQL---------
---------------CLENLRKELSAKHRSEMEDLQNQFQKEL--------AEQRAEMEK
IFQAKNQAEVS-LKNLEAQHQAAIKKLQETLQLEHCQYLQDLEVKFREKEKEKQ----LE
LENLQASYENLKAQSQEEIRHLWSQLE-----SVRINREELN-D----------------
------------------------------------------------------------
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-------------------------------------------PCVKHTLVEHHKEDLNK
AEEKIQLMKQELKRKEMEWELLQQDLKKEAEERLALMLLELREKAESEKQSVIKRFELRE
KGMKHLQDQQTA------------------------------------------------
---QILGLEKSLRDQQGRLRQLEQELAGDEA----LCSQCGQQSSM------AEEGECTL
LPHDEEDCALQLMLARNRFLEE----------------------RKEIMEKFAAEQDAFL
QDIQGKHAHEL----Q----LLQQEHQQQLLSLRTELEKKQQAELAEQRTSLESEQRVLF
ENHMAELHVKHAAEISALETRHLSNLDALESCYLADIQSVQDEHRKALELLRVELVEQLQ
KKDSCHQAILTQELEKLKLKHDGELQSLKDNLRIAMSA--KHPEPLTAQTI---EVQGVP
QESLASALHH---QRCLLEEDKVASLDR---------------VDTEVLLLE--G-----
------------------------------------------------------------
----------------------------QATPQQLG-----------DIHAVETQKSQ--
----IELAKPPEVQG---QAAQVS-VPFLSLHQEVEQCHAELERLRQRRERENQEGAALI
CMLRADVDQSESEGKVLRDALRRLLGLFGETLKAAVALKSRISERVGLFLDHMGATEA--
-GQAP---------EAAPALDEIWSD--TIL------LGLDRTLPEGA------------
---EMSSVAEISSHVCESFLLNPESTLECEQPIRKFYQSLGMAVDGLLEMALDSSRQLEE
ARQIHSHFEKEFLHKTEETAQLVQKQQEMLERLQEESAAKAELVLELHTAQSLLEGFKVE
KADLQEALGQKEELEQQLVLELESLRQQLQQAA------QDLAAIRQENATLWSQKEALA
AEAEARE------------AALQKEMESLTREQSEARKQSEKDQASLLSQMKILESELED
QLSQHQGCAQQAEE-VATLKQQLLALDKHLRSQRQFMDEQAVEREHEREEFQQEIQRLEE
QLRQS--ARPRLPDNLDSQ------VGCLDEEIELLQEKLREKSDGFNELVIKKELADRQ
LLTQEEEI-------KYLEATHANTQRQMAQLQEELEKQKKTVKEL-QDKEALKRQQVSD
SLLMSMSQ-STLSEGNGPLPPLEHS-PEDLEVQLETTQRKLLQHET--------------
------------------------------------------------------------
-----------------------------------EIGYSRSSEVEELKAIIENLQENQE
RLQKDKTEEIEQLHEVIEKLQHELTLMGPVVHELSDCPADSLH----SELLSLQSKGPG-
-----------------------GQALQAELEATCSAKEVLSQVLAEQVQGHNQALEALQ
QRLQAAEEAATQQLAEL-----------------GRIVTLREAEVEVMASRIQEFEAVLR
AKEAIIVQRDLEIDAMNKQGVAHSVELRSVLLA-LTRFSSVLER--------QPLAAP--
GEPPELQQLQVQCARLSRQLQLLYQRLLGCQGEPDQHQAHGGVSGG--------------
----SPH-------A------H--------------------------------------
--------MDTQ------ADTLHFA-VSH---------------------------CPYS
P---HL----------------------QGKEKQ-VEDCQLHKVSLIAQVKQLQEKLNQL
VCSMAFRNIDTEPPKFQQCSTL-PYLLENGSD--DGF-----------------------
-HNGEETDGLLPVDMFDFDKST---------------------QDLL-------------
--G-------GNKNRDFLVDS-KIPAFPTQENLALQDGPVSSQT----------------
-----------------------------SIHRSS--LLHTEEAEPQKHPVRPVDLSSWS
SPEVLRKDS-TLEPQLS---LPLTPCSGAMSLRSADTTPKDWMDS-PMGA-HASELLCYP
GVSP---QRTA-----A------------------------VS-AEHHHGETAPEKDIED
FVITSFDSQEPLRSP---------PLGLEKRSN-GSGNGDGPGTDVILTPGSVGPE----
---------DLTAGSAAA---ALNF-EGSPQALGTMKEK-EVHGKHVKALLQMVFDESHQ
ILALSENQELPRALSRGE------------PRALLDDCLRERQGLLELAP----------
EKEEKEPSDTCLAWSGGLLQAVQEAFE--K-------ELKPRSCS-SDLQDYSSLFKRLE
KIIQEQGD----LKEKPQEHLFPPDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTS
SEARGSQREHQLRRQVELLAYKV-------------------EQEKCIVSDLQKTLGKEQ
EKVSDVRKRLVAEQSTVQELKLELLEYKQENARLLESLGEMQQEILQLRYDPEHP-----
---SLTWASMLSISPHRSMLDGKENDLKA-------------ALEELECE----------
--HRKEQALQAQREEERQ---------------------RHLQWEGQSSKALE-ELKITL
EKQRSQN--SQLSVALKHERTA-KDNLQKELQIEC----------SRCEALLAQEQSQ--
-LCELQKSLEAEK-SHSSEL------LEALQHERLLTEQLSRSVQEACAR--QET-----
-QGHHNLLRKLKSEKARTLELQVMLEKVQQQAT---------------------------
---------------------------------------------QAQQQLEAQAQ----
----ERCAELRREKERELELQHQRDEHKIKQLQQK---VKELRWKEEVPWGDDS-----R
----LG---------AL---DLGRLQEQQQELEKIRQQLLCVAGLLTSFVNHTVDRTMND
WTSSNEKAVSSLVHTLEELKSELSIPASS----QKKVTAELQV-QLMDVLLK-DNNSLTQ
AVSTATREKAELCRAVSRLE---RT--LKHHVQRG--------------CSLSR-PGRCA
WKQDGAALPISPGHSNLGQPTL---------PVSEDTD-TCHVRMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKV--TASRPFTKFRTAVRVV
IAVLRL--RFLVRKWQEVDRKGALAQ-GKAMR--PGF-----RASRRQQSS---------
-----------SEARESLPTRDVSSGPAKDSAH-----------------------GAGL
AATPS---LKRSTSSPNSRLGRSLTASQDPEHSLTEYIHHLEMIQQRLAGVLPD--SAS-
KKSCHQKIKQ--------

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------------MEDEQEQRRRKVEAGRAKLANFRQRKTKGDCPNSKKKTAK--------
------RKGSAVHASVQEEG--SVATP-NSELPQ-GGA--VFESPSCS-------NTLEG
TRGASA----AQEQED-----------------CELDVT---------------------
------------------------------------------------------------
-----------------------------------------------------DL-----
------------------------------------------------------------
------------------------QGQQQ----T--QP-PPPQ-----------------
--------------------------------------------------TAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLREQH
AREKEE----MALRSGQEAAELKEKLRSEME-KNAQTIETLKQDWESEREL---------
---------------CLENLRQELSLKHQSEMEGLQSQFQKEL--------SEQKVELEK
IFQAKHEAEVS-LKNLEAQHQAAIKKLQEDLQSEHCQYLQDLEQKFREKEKAKE----LE
LETLQASYEDLKAQSQEEIRLLWSQLE-----SMKTNREELN-GSWDPVLAQASHLEELE
HLRSGFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLKDAEKTYQEDLTVFQQR
LQEARED-SLESTE-------ISSS----CVLPEETSG--REGKEPPDPLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLGQPKVQESLVEDCQVKLSK
AEEKIQQMKEEFQKKEAEWELSREELKREAEERLASMFLELREKAESEKLSIISRFEHRE
SSMRHLQDQQAA------------------------------------------------
---QILDLERSLMEQQGHLRQLEQELTRDDLL---PCSQCGQEPAM------AQEEKNGA
LLREKEDCALQLLMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDAQEKHNHEL----Q----LLQQGHQQQLLALRMELETKHRSELTEQLASSESRRQALL
ETHVAELQVKHNAEISALEKRHLSNLDELESCYVADVQTIRDEHQQALELLRAELEEQLQ
KKESCHREMLTQELENLKRQHAEELQSVRDSLRMEMSA--QHIENGKGPAA---DLQGAH
QQDPAMALHN---EGHLLVEDGDAVLRS---------------VDAEGLL----H-----
------------------------------------------------------------
----------------------------QAGPQELG-----------DAHTVEMQKSQ--
----AELAKPQELQASQDQVAQVRDKVF-LLNRELEECRAELEQLQQRRERENQEGTTLI
CMLRADLELAQGEGKALRDALRRLLDLFGDTLKAAVTLKSRISERAGLLLDHEDAADT--
-SDAR---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVCEISSHVCESFFISPENTLDCEQPIRRVYQSLSTAVEGLLEMALDSSKQLEE
ARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVE
KVDLQEALGKKEESEQQLILELEDLRKQLQQAA------RELLTLKEEKSVLWNQKETLT
NEAKERE------------AALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLAEE-VATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEG
QLRQA--ARPRPPGPRDSQ------CVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEEEI-------KRLEETNASIQRQMVQLQEELEKQKKSMEEL-KEKEILKQENMGD
LLLTTVSR-SGLDEAGCPMLPQGSS-SRGPEAQPDVTERALLQHEN--------------
------------------------------------------------------------
-----------------------------------EVVHRRNSEIDELKSLIENLQENQR
QLQKDKAEEIEQLHEVIEKLQSELSLMGPKVHEVSDPQAGSLH----SELACLRGEGLG-
-----------------------GQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQ
QRLQDAEEVAARHLAEL-----------------EHCVALREAEVEAMASQIQEFAATLK
AKEAIIEQRDLEIDAVNKWKVSHSLELEAILLA-LAHFRHALEQ--------QTCATP--
DEPPELRQLRVQCARLSHQLQVLYRPFLKCRMQLDQHQPHVASIGC--------------
----ANP------CA------D--------------------------------------
--------DELE------QEGVSNR-LAL---------------------------APHS
L---AA----------------------QAK-EE-LEDCPLGKANLMAQVRQLQEELDHR
VHSVASRDTNSETCKLQQ-----PNLSENGPR--NHC-----------------------
-CNGEESKPSPPDDVLNIAKTT---------------------WDVI-------------
--D-------IIKNQDLLVQV-EMPDFPTQEKLTSQGGPFSSQA----------------
-----------------------------SGHSGS--LLPEEAAEPQQDPVRALDLSSWS
SPEVVRKDP-SLEPQHS---LPLTPGVGTVSLHSVDI-SPDWTDP-LLQA-DVSGLLCYP
GKSA---SGQAPLWAVA------------------------PSAGKHHAERTATEKDVED
FIVTSFDSQELLTSP---------SHELARRSD-GSRKSDGPDIAMMLTLGSEGSE----
---------TPTTDLVAAAAAAVPFSRRFVQSPGAMKEK-EIHAKQMKALLQMVFDESHQ
ILALSESQDPSSALNKGE------------PRDPLDGFPRDSQALSEVTT----------
DKGEKESLETHLTWSEELLRAIQEVFA--REQE--KAELQPRPYG-SNLGDYNSLVQRLE
KVIQEQGD----PQ-KVQDHLCLSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIANELQKTLSKEQ
ETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRYGHVTW-----
-----SYCGTSSASAGRAVLDGKEKELKV-------------VLEELESE----------
--RGKGQALQAQQEEQQL---------------------RYLQREGQSSRALE-ELKLSL
EKQLAQN--NQLCVALKHERAA-KDNLQKELQIEA----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNSQEACAR--QET-----
-QVQHALLRKLKAEKTRALELEAMLEKVQKQAA---------------------------
---------------------------------------------HTQQQLEAQAQ----
----ERCVELRREKERELEIQRQRDEHKIEQLQRL---VRELRWKEEVSGGNGPCRGSPG
----RG---------SL---ERDQFQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSMPTSF----QKKMTAELQV-QLMNELLS-DNDALTK
AVGMATREKAELCRTVSRLE---KT--LKHHTQKG--------------CVLNR-QSKSS
LKQDGTDLQSSLRHSDPEWHSQ---------TTSGDTN-TCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TMSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALVH-PKSTR--HGH-----RTSQRQRSP---------
-----------SGPRASLPTRDTSSGPTKASRH-----------------------SPRS
AAAGSPGK-ERSTSTPSSRLERSLTASQDPEHSLTEYIHHLEMIQQRLGGLPPD--S-T-
QKSCHQKIKQ--------

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-------------EDEQEQRRKKVEAGRAKLAHFRQRKTKGDCVHSKKKTAK--------
------RKGSSVDAPVQEES--PLVA--KGGLLG-GGD--VCESTSCG-------DTPNG
AGAFAS----QTVADC-----------------CP-------------------------
------------------------------------------------------------
------------------------------------------------------------
--------R-LQ------------------------------------------------
------------------------HLRGH----YTAIP-PPQG-----------------
--------------------------------------------------SAESLHLLWL
R-LTGQLHQAQLELTQANLQKEKETALTELREMLNGRHAQELALLQSRQRLELELIREQH
AREQE----EMALRCAQETAELKEKLQIEME-KNVQMIETLKQDWESERDL---------
---------------CLENLRQELSGKHQSELENLQNQFKKEM--------AEQKAELEE
IFQAKNQAEFS-LKTLEAQHEVALRKLHEDLQSEHCQCLEDLELKFKGKEKEKQ----LE
LETLQALYEDLKAQSQEEIRSLWSQLE-----SARTNRQEPS-GEEFPPLARGSHVEELE
HLRRDFDQQ---------RQRER--TEHESELEQLRIYFEKKLRDAEKNYQEDLTLLQQR
LREVKEDSPVESVE-------ISSS----SALLEEASE--KDGKDQLDQLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLEQPEVKHNLVEAHQEELKK
AKEEIQLMKQEFKERAAEWKVTSEDLKRKAEEKLTLMLLDLRGQAESEKQSIINKFELRE
IEMRQLQDRQAT------------------------------------------------
---QIRDLAGSLAEQQGRLRQLEVGFTGDESL---QCGQCDQEPGGG--LAPTDKDWELA
MLRLKEDCALQLTLAQNRFLEE----------------------RKEIIEKLAAEQDASL
RETQEKHTREL----Q----LLQERHQQHVLSLTAELKTQHQAEMDQLRAAFESEQWALS
EARVAELQTKHAAEISVLETRHLSNLDSLESCYLSEIQAIRDEHRRALELLRVDLEGQLQ
KKNSSHQMILTQELGKLKLKHDKELQSAKDSLRIETSA--KCVGNLKAPAP---ELQGAH
QEELAVALH----EG-LLEEE-----------------RSLTSVCGEVLLLEQQH-----
------------------------------------------------------------
----------------------------QEALQELG-----------DVHV---TELQRA
--ASRASLSLQL-QEKNNQILQLKDQIV-TLSHEIEQRRSDLEKLQQRRERENQEGANLI
SMLKADVDLSHSERIALRDALRRLLGLFGETLKAAVALKSRIGERVGLCLEDQSPLDAQP
GAQVP---------SAAPALDETWPGPDAAL------PELDGTFPECA------------
---EMSSVAEISSHVCESFFMSPESTLECEQPVRRIYRSLGLAVDGLLEMALDSSRQLEE
ARQMHSLFEKEFSCKNEETAQVVRKHQELLERLEEENAARARLVLELHKAEGILEGFKVE
KASLQEALGRKEASEQGLVVELESLREQLQWVT------QQQAELREENATLWSQKEALA
TGAEERE------------AALQKEVEYLTKEQSETRRQFEKDRSALLSQMKVLEAELEE
QLSRHRVCAQQAEE-LSALRQQMGSLDKHLRSQRQFMDEQAVEREQEREDFQQEIQRLEE
QLRQV--ARPQPRGPHDSH------RAQLDEEVELLQEKLREKSDGLNELVIKKELADRQ
VLIQEEEI-------KRLEETNANTRRQVIQLQEELEKQRKTVKELQQDKEALQEQQMSN
LLLVSTLQ-SKLDEGKCPLPSAGSC-PEGPEVQSEAVQRVLLQRET--------------
------------------------------------------------------------
-----------------------------------EVMYSRSSEIEELKSIIENLQENQE
RLQKDKAEEIEQLHEVIEKLQRELSLGGLAVHEVSDCRAEDLQSELERGLLCLQAEGAEA
H----------------AA-------LEGELQAALAAKEALSQLLAEQERRHGQALEALQ
QRLRGAQEAAAGQLVEL-----------------RHGTARREAEVQRLASQIREFEAALK
AKEVKIVERDLEIEAMNKQKSAYSTELQNILSA-LTRFRRALEQ--------QPLAAA--
DEPPELQRLRVQCARLSRQLQTLNQRFLRCQEALDKPQEHGAL-----------------
------------------------------------------------------------
--VGCGHPCLSF------QPEQEGL-QSLPPASLC-------------------------
----------------------------APLEQL-LESCQLQKIDLITQVKQLQEKLNCL
VRSLSA-----EDSESQQPLAF-PRALESSSS--DSS-----------------------
-KNSEQTDRSPPIDAFNIDKTS---------------------CDLI-------------
--D-------IIGNQDSLLRN-ELPKVPVEDKIDLQDGSLCLQA----------------
-----------------------------SLHSSSRDLTHTEGAEPLKNVLRAMELSSWS
SPEVIRKDS-TLEPPPS---LPLTPCSDALSQRSPDASLRDRISTSLLQA-DQSGLLCYP
VRSA---AQTAPRWAEA------------------------PSAD-HHVQRTAVEKDVED
FIITSLDSQEKSGSP---------PLGLEGRSD-GSENSDGSGFGEILNQGSERLK----
---------TPTAGPPV----PPPASRRFRRPLEAMREK-EVHPKQVKALLQMVCDESYH
ILALSEYRGPH--------------------CAPLECFPREGQGPLEAVPALRGHPTPAP
QKGEKEPADVCLDWRGEFLRVIQEAFE--KEREMLKVELQPRVGD-SDPRDCSCLLERLE
KVVQEQGD----LQEKSLEHLRLSDRSSLLSEIQALRAQLRLTHLQNQEKLQQLCTALTS
VEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLNEEQ
EKANDVRKLLVVEQNAVRDLKSELSECKQDNERLLASLNDVQKEVLQLR-----------
-----------------SVLDSKENDLKA-------------VLQELESE----------
--RMKERALQSQLEEEQL---------------------QHLQREGQSSKTLE-ELRISL
EKQYAQS--NRLCVALKHEQTA-KDNLQKELQIEY----------SRCEALLAQERSQ--
-LSELQRSLEVEK-GRSLEL------SEALQHERLLTEQLSRRTQEACAH--QET-----
-QVHHALLRKLKDEKARVVELQ--------------------AM-L--EKVQQ-------
------------------------QAMRSQRQLEA------------------EVH----
----KRCQELQKEKERELELQRQRDGHKITQLQQT---VRELEAKEAA--HL--------
---------------CP---ESQRLREQQQDLEKIRQQLLCAAGLLTTFINQTVDRTISN
WTTSNEKAVTSLLHTLEELKSELSMSSSS----QKKMTAELQI-QLVEVLLK-DNDSLTK
ALGAATQEKAELCRAVSHLE---KT--LKHHLLKG--------------CALRK-SDRSA
WKQDRTVLQSSPRQPDPGLPTP---------AASDEAK-VCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKV--TTSRPFTKFRTAVRVV
IAIFRL--RFLVKKWQEVDRKGALVR-GRAPR--PGFLG--PQQ---QQSP---------
-----------PETS-ESPTRDVSSSHTRD--P---------------------KSSPQS
K-AGNVPVVEVSNPSPNSRSERSLTASEDPEHSLTEYIHHLEMIQQRLAGVQPD--STS-
KKSCRQKIKQ--------

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-----------MDEDEQEERRRKVEAGRAKLASFRQRKTKGDCPNSKKKTAK--------
------RKGSAVNAPVQEEG--SVAPQ-NSELPQ-GGA--GFESTSCS-------NTLEG
TRGAFA----AQERQD-----------------CELDEP---------------------
------------------------------------------------------------
-----------------------------------------------------GL-----
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------------------------QAQQQ---QPQPQP-QPTQ-----------------
--------------------------------------------------TAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELMREQL
AREKEE----VVLRCGQETAELKEKLRSEME-KSVQMIETLKQDWESERQL---------
---------------CLENLRKELSAKHQSEMEGLQNQFQREL--------AEQRAELEK
IFQAKHEAEVS-LK--ETQHQAAVKKLQEDLQSEHCQYLQDLEMKFREKEKEKE----LE
LENLQASYEELKAQSQEEIRCLWSQLE-----SVKTNTEELN-GSWEPCLAQDSHLEELE
HLRSDFAQQQ--------QQERR--AQHELELEHLRVYFEKKLRDAEKTYQEDLTLFQQR
LQEARED-SLESGE-------ISSS----CIFPEETSG--RGRKEQPDPLDL--------
------------------------------------------------------------
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---------------------------------------QLEQLKVKHSLVEDHQVKLNK
AEEKIQLMKQEFQKKEAEWERSHEDFKRDTEGRLTSMFIELREKAESEKQSIISRFEHRE
SGMRHLQEQQAA------------------------------------------------
---QILDLERSLMEQQGRLRQLEQELTRDEVL---PCSRCGQEPLM------AQDEEHIM
LLRVKEDCALQLMMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDTQEKHAHEL----Q----LLQQGHQQQLQALKIELETKHHSELAEQLASLESKQQALV
ETHVAELQVKHNAEISTLQMKHLTDLHAAKSFYLTDIETIRDEHRKALELLQAELEDQLQ
KKDSSHKEILTHELEKLK---HEELQSAKDSLRIKIHA--KHTEEAKGLAT---DMQGTQ
QEELAMAVHN---QRHLLGKDGNAALGS---------------VGAEVLL----H-----
------------------------------------------------------------
----------------------------PAVPQELG-----------DPHAVEMQKPQ--
----AELAKSQELPASQEQAALVRIPVF-SLSREVEECRAELERLQQRRERENQEDTTLI
CMLRADADLAQSKGSVLRDALRRLLGLFGETLKAAVTLKSRISERAGLLLDHVDATDT--
-SDAQ---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVSEISSHVCESFFMSPENTLECEQPIRKVYQSLSTAVDGLLEMALDSSKQLEE
AHQLHCCVEKELRHRNEEMAQAVQKQQELLEHLRQESAAKDGLTLELHMAEGLLEGLRVE
KAELQEALDKKEESEQQLILELESLQKQLQQVA------QELVTLREENSVLWNQKETFT
NEAKERE------------AALQKEVESLSRDQWEARKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLTEE-VATLKQELAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEE
QLRQA--ARPRPPGPRDSQ------VG---QPVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEKEI-------KRLEETNVSLQRQVAQLQEELEKQKKNMEEL-KVK--FWQELTSD
LLLPPVSQ-CRLDEAECPKPSQDSS-SRGPETQPEVTESTHLEPES--------------
------------------------------------------------------------
-----------------------------------EVVPSRNSEIEELKAIIENLRENQE
QLQKDKAEEIEQLHEVIEKLQSELTLMGPKVHELSDHQASSLH----TELSCLRAEGQH-
-----------------------GQALWNELEAAQAAKEVFGQLLADQAHGHSQVLEALQ
QRLQDAEVVAAKRLAEL-----------------EHCVALREAEVEGMASRIQEFEALLK
AKEAIIVQRDLEIDSMNKWKATHSLELETILLP-LAHFRRALEQ--------QTLATS--
DEPPELQQLRIQCARLSHQLQVLHHRFLQCQMEPDQQQAPVAPADC--------------
----SSP------GA------D--------------------------------------
--------AQWQ------QDSVSMG-LAS---------------------------FARS
L---SS----------------------QAKEQQ-LEDCQLGSGDLIIQVQQLQEKLNHL
VHSMASRDTSMENPKSER-----PSLSENGSS--SDC-----------------------
-HNDEDISASLPIDVFSIGKTT---------------------WDVI-------------
--D-------VIKNQDLLAQV-EMPSFPTQEPLTPQGGSLSSQV----------------
-----------------------------SVHSDS--LHPEE-AEPQKDPARALDLSSWS
SPEVLRKDS-TPEPQHS---LPLTPCTGTVSLHSVDTSSQDWTDS-LQLA-DASGLLCYP
GKSA---TAQAPLWVVT------------------------PSAENHHVERPATEKDVED
FIVTSFDSQELLTTS----------PHELTRSD-ATGKSDCPSGGMMLTLGSGGSE----
---------TPRSSPVAA--AVVPFSRRFDQSPGAMKEK-EIHAKHMKALLQMVFDESHQ
ILALSKNQDLPNSLSKGE------------PRDPLDGLPRDRQALLEATA----------
DRGEKEPSETCLTWSGELLRAIQEVFA--REQE--NAELQSRPYG-LDLGDYNVLFKRLE
KVIKEQGD----LQ-KV---QCLPDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLNKEQ
EKASDVRKLLMVEQSAVQDLKSELHACKQENTRLLESLDKVQQEVLRLRYGPSPY-----
-----TALMAARCFPPRAMLDGKENELKG-------------VLQELECE----------
--RGKERALQAQHEEQQL---------------------RHLQREGQSSRALE-ELKMSL
EKQRAQN--NQLCVALKHERAA-KDNLQKELQIES----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNMQEACAR--QET-----
-QIQHALLRKLKAEKARALELESMLEKVKKEAA---------------------------
---------------------------------------------HTQQQLESQAQ----
----ERCVELRKEKERELELQCQRDEHKIEQLQQM---VRELKRKEKVPGGDGACRVSPR
----LG---------SL---DLDHVQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSIPASS----KKKMAAELHV-QLMNELLR-DNDTLTK
AISMATQEKAELCRTVSRLE---KT--LKHHMQKG--------------CILSR-QSKSS
GKQDGMVPQSPLRNSDPEWHTA---------TTSMEAN-TYNTKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TTSRPFTKFRTAVRVV
IAIQRL--RFLVKKWREVDRRGALIH-GKGSR--QGH-----RMSRRQHSL---------
-----------SETRASLPSKEVSSGHTKDARH-----------------------SLRS
LAAVPLGKVERSTSSPNSRLERSLTASQDPEHSLTEYIHHLEMIQQRLGGLPAD--S-T-
QKSCHQKVKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------LTPDG
AGWASA----AQLEDQDGGKREDLEQLQQ----------------KQI---SDHPPEQR-
------------------------------------------------------------
----------------------GIFTISDH-HPEQCG------IFTI-SDPHQEQH--GI
FTISDHPPEQREIITVSDHPPEQPGIF--------------TVSD----------PHPE-
-------------------------------------QHE------IITKECE-RECELA
IADLQSSREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KGRKAHVGELS---------
----PERHKESLPCFQAELEESRGHLLEAPESPLCIQH---EGHVSDRCCAE------TL
ALGQGW---H---LEPS--KGHSQELPWVHLQGVQDGALEADTEVAAIVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKAKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVTKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRK
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGRELPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIRTIREEHRRALELLRADFEEQLQ
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLQTAASR--EL---PGTVA---HEL----
------------------------------------------------------Q-----
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----------------------------GAHQVEFGGEKKAALHEKEETLQLQSAQTQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEVLQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKEALAGKEHSEHRLVLELESLRRQLQQAA------QEQAVLREECTRLWSREEATA
TDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNISIRKKVAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLSSTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSTLLQRESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLVM-QNSQTAVRLGELQEENVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSQLLADREHRHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRHALEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLQVLHQRFLRCQVELDRRQACRTTAHTW----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMMLEDAPLCK------QEGVMSV-LTICQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KSEEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPTDACDASTAT---------------------GGVT-------------
--D-------VIQNRDSLIPG-EMPDFPIQEKSECQDRSLSSPA----------------
-----------------------------SMLGGSRHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQT-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRMAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGLGFGARLSPGSGGPE----
---------APTAGPVT----PAAVSGRFQPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPSRKGDEVQEGLLCGG-K----------
TQ---DVPTVCPDWRGELLQVVQEAFE--KEQEIQGVELQPRLSG-SDLGGHSSLLERLE
KVISEQGD----LQERSLEQRRLPDRSSLLSEIQALRAQLRMAHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANSVQKLLVAEQSVVRDLKSELCESRQENERLSRSLCEVQQEVLQLR-----------
-----------------SMLSNKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LGELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDA-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVDALHTQKRELRCSLEREREKPAWLQAELEQTHPRLKEQEGRKAARRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLELKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEVMRQRLLCAAGLLTSFASQAVDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDILLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-LERAA
WKPDETAPQSSLRRPDPSRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHIGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

MEDDERDERRRKVEAGRAKLAQFRQRKTKGDSPGSKKKASKRKSSTVHEAVQEKEEERAV
EPPEGELPSDVAQSVAGPEPADGVSGAPEAKAERGLSSLGTPKNSITELIVQEPGFEDNT
PSLATEPRAQEATIKMLEEKLVDKQEDIDLLSQEVGELQAQLAQCSEAAQLQQELEMAVQ
ERDRIIVQLTSNLQLVRQNHEDDQQEVLLLASQIQGLQLQLQE--NSELLKSKTPAKGCL
SQSQLQAAASLQGPREPN-----PPSQGWDLEKLPAS--------SQKNFKEKEAAFAQM
EEHGKSASQQPSQVVSEKEGMISSLQDQLGLAGNAGASAQHALSVKSSKVIELKR-----
--EKQDCMEESQVPPPREACGPL-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------LQNLGDELGETCELG
VAEARKAYGDTDGKSWGASPVPGLRGSEQQSLGGLG----------IDFSSQFLELAACA
MPESHRATFQEERNGAEHLENDDHKKRKLPSAEKIVEEALASKGDDEIQ--NLLNFHVRE
SNEKMLQETENSGELRLKHGMTLGQANWEERT----LLGQKAELQGMPRKLCLRPRESDC
HEVGCRDGLQTCCLNSEEENPSLELGEHEDDQLEVGSLQDEVSSEESRMEETRDLMEKYL
VSTERDQSRVSEAPDHFDLETALQRRSERES----L-----DFLSDELIIGLDGNIDSNV
LFEGNSVQVESYAAPWTDRQEPSGFSQGDLSEILELMDKDKAYLMQRCVKLSHLLRE---
KE---LALKTFSQEVEEEVAEERWWEGKHRLLNVLSQEGGGSCDE---------------
------------IVPRLKGEEHIKLGTTAGGITDLAGWASVTHQPHCHVMDEVSQKEEGG
RSGKIASASVGLEALCSQE--------ENR----PP----GQLRVHKPRS--HM-PAGCS
SQKITLEESLLQEVETLKAEMAIKENLFTQVVEEKNTLEEKFTKDRENLE--E-NIL---
ELIEK-IKCLEKGLGHEKVGFAGKSTSVLSEDQKLDAKRKVQESDFLSTENSPIQQTISL
KNAQVE-PEW---LLQEEAQK-----ATCALEDVR-SELSSYHEK---QMSQMKHQH-EQ
ERTELRREHQKEVEATRKEMKEKLEEQQ------QRWEQERREQISAIKKIHE-REHDRE
IAELVSKHKEEMTQLRDELHSKHQQMMEGLQQQMQASHRAEMQQAQLQAQTLHTLELEAL
RLSLSNMHTAQLELTQANLRKEKETALVELREMLNDKRAQELALLQSRLQFELEHVREQH
RKEKEE----MALKHQQERADLGKKLELQVET-QARTLETLRGDWASERDS---------
---------------SLRRLQEELATKHQAEMESLRGALRAQL--------AEQQAELDK
MGHDKSQAEAT-LRSLQAQHQLALQDLRQELQLQHDQYLEDLNLKCREKQ--------TE
LDTLQASYEELKVQSHREIQQLWAQLD-----STRASRHELN-ELKEQLVARTSHVEELE
RLKHGFEQR---------QRQWR--NEHETELEQLRVYFEQKLRDAEESYREDLHLLQQR
LREVREDSFLDSED-------VSLS----VGFVEEEAE--MERKAHLEQLILQ-------
----LEQHKDGIAHLRLQLEGKHREESATLEASLRARHEE--EHSRR------DWM----
-GVEAG-CLGLGILS---QQNHTPDPVWLHLQCAQLAARQVEAEVAERVSV-LEDDHLAR
VAQLQSEEQLISQLREQVDLARRENMELQ-EKVQQEVRLREEAEKMRCRLVKDHQTEIER
MKEEIRQMIQKDQGREDAWRAQSE-------ESLAALALELNGKAEQERQALRQALEAHV
TELEQLRDRQAA------------------------------------------------
---DIARLET--------------SLGEA-------------------------RAQEEA
TGRLREECALELQANRARFLEE----------------------QREMMQKATEKQDVLL
RELQDKHASELQIQKT----ELQAQHQAQLEARETELQAQHQAQLEARETELQAQHQAQL
EARETELQAQHASETSGLEAKHLSNLDSLESCYLSEIQTIQEEHNRELEQLQARLEEQLR
EKDTQYEELLAQE----KEKHQQELQQAQESLKIEMTT--KHIEKLKALTA---QLQDAH
QEDLE-------------------------------------------------------
------------------------------------------------------------
------------------------------------TEKRAALREAEELLALEREKAQAL
CQRE-EALT-LQLQEQSGLILQLKEKVL-SLNSEVSESHEELKKLQERRHREHEEGTNLL
SLLRSDMDHTQNERKTLQETNQWLLSLFGDTLKATIAMRSQISKRIGICLDEDS-LSK--
-ESRP---------MG-----TPG---QLAQGAC---ELQCCTMPECDE----TLLPEC-
-DETLLPGNDISCHVRESFFLSPEVTVECEQPIRRIYQSLGAAVDNLLEMTLDSNKQLEE
TRERHARFEKEFNRKNEETAQVARQHQELMDCLNQESAAKNQLAVELHKAEGLAEGYRAE
KAALEEALAQKEESEHRLAVELENLKAQFQALT------REQAKLKEEQNLLLRQKEMLI
VEAEEKA------------AALRKEVEHLVREQAETRQQSEKDCASLRSHLRALELEVEE
QLPQQQELVRQAAE-IQDLRQQIVSLDKHLRNQRQFMDEQAIEREHERDEFQQEIQKLEE
QLKQ-QPPKSQPWGEPWDSE-----V-------ESLQRQLREKIDELNELVIKKELAERQ
LLAQKDEI-------KNLEDANAEIRKKVSWLEEELEKQKKIGKELRQDKEALQEQQMNN
LIQISTLQ-SKLDEAKHLQPVQGSPSEEDLREQLRAEQTALQLKAREVQNLEDELGELKK
NLTSKSEEIVQLNLELAL-QNRQISGSIQELSAENAD-----------------------
----------------------------------LKVMGDTSAEMEELKAIIDNLCENHE
RFRANKAEEIERLHEVIEKLQKELSVLGPALHELSDSQGDSDGS----QAENLQRELAQG
LSSVQ---AREER------LPLPPDE--------------LG-QRLRDESQFRLRVAALE
QELQDIRDASAQ------------------------QLTLKEAEARKLAALARRWK----
---TAARQKEAEVEALNEERGVLLAELETLVMA-CSRLEKELER--------KRPAGP--
HEPPELQMLRAQCVGLNLKLQALSQRLVTYQLELDQHQACGPQCR-------V--QAL-G
AS----------LMEPGRSAGQR-GRFWATDHWAL--MLPSGPGP---QLPLWESPTVSS
K-------------PSSSKESGLSV-LTVCQEQLESEL--LLMKA-----KMQMGAEDRS
KLI--Q-------------------------QKP-VDVCQLQKGDLITQVRHIQEKLHHL
IRSISCRDSHVQSPPPQGPVSTV---LQHSWTLHDRTESPDPPGQGGPTPTLDKTPDAWL
SSPSDADP-------------------------------STPDFSCS-------------
----------------E-------------DCVAAQRAPPCTETPGS---PPPGGSAR--
--------GSPPSA--R------------SAEEASQDADPLDAVQHFRDTILDMDSSSLG
SPELVRKDS-TLDRLPSV---HLTPLSQAADLQSPD----SAWR-SLGLQ-DSSGCLAFP
ALPGLEASPQPSLTEKARPRAGRATEA-TVSEKDVEDFILTPSNSQEHLEST----AP--
GERGESDGHDNSESG---------RSRLACLGG-GGRDGPGVRAPG----GTPPSG----
---------PPGPRPL-PPVAASSLCPPWR----------------GPALLKMVCDESQQ
ILVLSKCEAPASDLGSALP-APTPDCFQKERQGLLDAEPSD-------------------
---------TGFDWGGEFLQAVQEVLE--KERNMLKIELQSKLC----------------
-------------------SLDSGDERSLLEKLEDVVK-----------------EQVGG
AP---SVGGAALPRDIEYQIFLKGQDYSPPLLSFVGNSSFQQRLNSFLLSSHPKSISHFH
HHDEHHTKLIQ--------TPQMQFETEQELEDLKKQKQKERRGIGGLFTASPSSFSDTR
YKTFFIQLSYWSVGPSPFHLEAPAVPLWGPALANGLGPPPRPSLSTLEPELSPRKPAEWG
APHPKSSGSRALLPPRVSVERPTAFLFGQWSASGPSSAPSPWLPRQVVLRLLE-SLASHP
PSAWARGPLGSLLLPFRGSLLSRQSPYILGLRVIFEPLGGFSSKTCLCRYFFPFENQQDQ
NIVAIVASLSLFLCQHSLPCSSGSNPFSSPASSDLGAVRLEA-RPASPPCSFHRPPLSCP
WAFARAARVPLESLPQA--PGSRLPRQGLQRGWLGRVASGRGPS-GC---------VTRR
----LLVS----------------------------------------------------
---------RSEGWQRELELQRQRDEHKIQQLQQT---ISELQNDKGFVPSRGWQE---C
G---------VGVPLPPNTEK---LKEHQEQLQSVRQQLLHAVALLTSFMNQTVNRTIND
WASSNEKAVTSLLLTLEELKSELMMTLPQK------KNTQAQI-SLIDVLLK-ENGSLTK
ALSTMTQEKVELCKTVSKLE---RT-L-KHHLQKGCGH--------------IV-RAGPG
GLVSRRAAVSGAPDSRLP-SQYKYV------DRIGTLQKVDKTTMRRLYLHFLRAESFPE
GPSFIRKRYLLLLIGGFQDSEQETLSMIAHLGVFPSKLDKRAF--SSRPF-TFRTAVRVV
IAILRL--RFLVKKWQELDRRGITAA-GRLPR--PPSKLRAPHVPW-QTRPMGRMFPLTS
HRASPVVLGNAMEGVSRPRGWGGRF-----------------------------------
----------SPHPLAPPLERPPRRNSQDPEHSLTEYIHHLEIIQQRLGGVQPE--LS-S
KKPGHLKTKK--------

------------------------------------------------------------
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------------------------------------------------------------
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--------------QKVTVRIRRKRRRRGRLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--VCKSTSCD-------DTPDG
AGGAFA----AQVDLLIL---------TQ-------------------------------
------------------------------------------------------------
----------------------------------------------KWQKAGSEQR--GI
FTVSDHPPEQPGFFTVSDPHPEQREVITKVFFKQARATMLMTV-----------------
---F--------------------------------SCEC-----WTTFFECK-QECELA
IADLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKEGEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KGRKDHVDELN---------
----PEQHKESLPCFQAELEESHRHLLEAPESPLCIQH---EGHVSDRRCAE------TS
ALGQGW---H---LEPS--EGRSQELPWVHLQGVQDRALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPA-------AQDGELA
ALHMKEDCALQVILARSRFLEE----------------------RKEITEKFSAEQDAFL
REAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETGHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLQ
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLRTAAST--EL---AGTVG---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKAALREKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGVNLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSAAEISSHMRESFLVSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
TDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNINIRKKMAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSALLQRESEVLYLKEQLEKMKG
DLESKNEEILHLNLKLDL-QNSQTAVRLGELQEENVSLK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LAHIRRVLEQ--------QPLAAG--
VEPPELQRLRAQCARLSRQLHVLHQRFLRCQVELDRRQACRTTAHTR----------VPG
AHPQPRVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMTLEDAPLCK------QEGVMSV-LTICQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DGS-----------------------
-CDGEEPDTSAPIDACDASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SMLGGSCHQSHAAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQP-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRTAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGAKLSPGSGGPE----
---------APTAGPVT----PAAISGRFQPLPEAMKEK-GVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVQEDLLCGR-K----------
TQFCSDVPTVCPDWRGELLQVVQEAFE--KEPEIQGVELQPRLSG-SDLGGHSFPLERLE
KVISEQGD----LQEKSLEQLCLPDRSSLLSEIQALRAQLRMVHLQNQEKLQHLRTALTS
AEARRSQQEHQLRKQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQESERLSRSLCEVQQEVLQLR-----------
-----------------CTLSRLIRCLP--------------------------------
--------------------------------------------------------SCVF
ATQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERGQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDA-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------TAGLD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAMDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
VAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--A-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAK--------
------RKGSAVNASVQEES--PVTKE-DSALCG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQPEDCDGEKREDLEQLQQ----------------KQV---NDHPPEQC-
-GMFT-------------------------------------------------------
------------------------------------------------------------
------------------------------------------VSD----------HQPEQ
RGMF--------T--------IS-D--------HPGEQRG-----MF-TKECE-QECELA
ITDLESGREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAERA-LRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASRVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGAREDAPLDSVE-------VGLS----CVGLEEKPE--KGRKDHVDELE---------
----PERHKESLPRFQAELEESHRHQLEALESPLCIQH---EGHVSDRCCVE------TS
ALGHEW---H---LEPS--EGHSQELPWVHLQGVQDGDLEADTEGAARVLG-LETEHKVQ
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETHLKDDLEKVKHNLIEDHQKELNN
AKQKTELMKQEFQRKETDWKVLKEELQREAEEKLTSMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQDLTSDDAL---HCSQCGREPPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHAREL----R----LLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALL
AARVAEMQTKHAADLSALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLQ
KKDSLHQTILTQELEKLKRKHDRELQSVRDHLRTKVST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GVHQGEFGSEKKTALHEKEETLQLQSAQPQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIQECRSELEVLQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAVTLRSRIGERVGLCLDDAG---A--
-GLAP---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLMEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESTAKAELALELHKTQGTLEGFKVE
TADLKEALAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSQGEATA
TDAEAREA------------ALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--AKPQPWGPRDSQ------QAPLDGEVELLRQKLREKLDEFNELAIQKESADRQ
VLMQEEEI-------KRLEEMNINIRKKVAQLQEEVEKQKNVVKGLEQDKEVLKKQQMSS
LLLASTLQ-STLDAGRCPEPPSGSP-PEGPEVQLEVTQRALLRHESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLDM-QNSQTAVSLRELEEENTSLK---------------------
------------------------------------VIYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERRHSQALEALQ
QRLQGAEEAAELQLAEL-----------------ECNVALREAEVEDMASRIQEFEAALK
AKEAMIAERNLEIDTLNQRKAAHSAELEAVLLA-LARIRRALEQ--------QPLAAG--
VEPPELQWLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATAHTR----------VPG
AHPQLRMDGGAKTQVTGDVEA-------SHDAALE--P--VVPDPQ-------GDLQPV-
-LVTLKDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDGG
----------------------------KGKEKV-LEDCQLPKVDLVAQVKQLQEKLNRL
LYSMTFQNVDAADTKSPWPMAS-AHLLESSWS--DDS-----------------------
-CDGEEPDISPPIDTCDANTAMGGVTDVIKNQAIDACDANTTTGGVT-------------
--D-------VIKNWDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SVLGGSHHQSHTAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLGDRADTSLPQT-QGPGLLCSP
GVST---AALALQWAESPP-----------------------ADD-HHVQRTAVEKDVED
FITTSFDSQETLSSP---------PPGLEGKAD-RSEKSDGSGFGARLSPGSGGPE----
---------ARTAGPVT----PAPISGRFQPLPEAMKEK-EVHPKHVKALLQMVRDESHQ
ILALSEGLAPPS----GE------------PHPPRKEDEIQDSSLHGG-K----------
TQ---EVPTACPDWRGDLLQVVQEAFE--KEQEMQGVELQPRLSG-SDLGGHSSLLERLE
KIIREQGD----LQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKASGVQKLLAAEQTVVRDLKSDLCESRQKNEQLSRSLCEVQQEALQLR-----------
-----------------SMLSGKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACMH--QDT-----
-QAHHALLRKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQ-KHCEALKREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSVEARQSPA
AAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEAMRQRLLSAARLLTSFTSQAVDRTVND
WTSSNEKAVMSLLHTLEELKSDLSRPTSS----QKKMAAELQF-QFVDILLK-DNVSLTK
ALSTVTQEKLELSRAVSKLE---KM--LKHHLQKG--------------RSPSR-SERSA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFTRFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAPR--T-----GPRARR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GRRL
AAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPD--STS-
KKSCHQMIKQ--------

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-----------MEEDEQEERRRKVEAGRAKLASFRQRKAKGDGPNSKKKTAK--------
------RKGSAVNAPVQEEG--SVATQ-NSELPQ-EGA--GFESKSCS-------STLEG
TRGAFA----AQERQD-----------------CELDET---------------------
------------------------------------------------------------
-----------------------------------------------------GL-----
------------------------------------------------------------
------------------------QAQQQQ--QPQLQP-QPPQ-----------------
--------------------------------------------------TAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELMREQH
AREKEA----VM----QETAELKEKLRSEME-KNVQMVETLKQDWESEREL---------
---------------CLENLRKELSAKHQSEMEGLQNQFQKEL--------AEQRAELEK
IFQAKHEAEVS-LKNLETQHQAAVKKLQEDLQSEHCQYLQDLEVKFREKEKEKE----LE
LETLQASYEDLKAQSQEEIRHLWSQLE-----SMKTNREEVN-GSWEPPLARDAHLEELE
HLRADFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLRDAEKTYQEDLTLFQQR
LQETRED-SLECGE-------ISSS----CIFPEETFG--PERKEQPDPLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLEQPQVKRSLVEDHQVKLNK
AEEKIQLLKQEFQRKEAEWERSHEALKREAEERLTSMFLELREKAEREKQSIVSRFELRE
SGMRHLQDQQAA------------------------------------------------
---QILDLERSLMEQQSRLRELEQELTRDEAM---PCSQCGQEPLV------APDEEHAT
LLREKEDCALQLMMAQNRFLEE----------------------RKEIMETFAKEQDAFF
RDAQEKHTHEL----Q----LLQQGHQQQLQALRMELETKHHSELAVQLASLESRQQVLL
ETHVSELQVKHNAEISALEMRHLSSLEALESCYLADIQTIRDEHRKALELLRAELEEQLQ
KKDSSHIELLTRELEKL--KHDEELQSAEDSLRVRMQA--RHTGTGKDPAT---DLPGAQ
QHP-CQAAHN---CLPLLEKDGHAALGS---------------VGAEVLL----H-----
------------------------------------------------------------
----------------------------QAVPEDLG-----------APHTVEMQKPQ--
----AELAKPPELQVSQEQAAQVS-QVF-SLSRELEECRTELERLQQRRERENQEGATLI
CMLRADADLARSEGKVLRDALRRLLDLFGETLKAAVTLKSRISERAGLLLDHVDAADT--
-SDAQ---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVSEISSHVCESFFMSPENTLECEQPIRKVYQSLSSAVDGLLEMALDSTKQLEE
VRQLHRCVEKEFRHRNEEMAQAVQKQQELLERLRQESAAKDGLTLELHTAEGLLEGLKVE
KADLQETLGKKEESEQQLILELENLQNQLQQAA------QELATLREENSVLWNQKETFT
NEAKERE------------AALQKEVESLTRDQWEARKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLTEE-VTTLKQQLTALDKHLRSQRQFMDEQAAEREHEREEFQQEIQKLEE
QLRQA--ARPRPPGSRDRQ------VG---QHVELLQEKLREKLDGFNELVIKKDFAEQQ
LLIQEEEI-------KRLEETNVNIQRQMAQLQEELERQKRHMEEF-KDKEVLKQEHVSD
LPLPPVPQ-CRADEAGFPVPSQDSP-PRGPETQPEVTERALLQDEN--------------
------------------------------------------------------------
-----------------------------------EVVPSRNSEIEELKAVIETLREDQE
QLQKNKAEEIEQLHEVIEKLQSELTLMGPKVHELSDHQANSLH----DELSCLHAEDRR-
-----------------------EKDLQNELEAAQAAKEVFGQLLADQAHGHSQVLEALQ
QRLQDAEEVAARRLAEL-----------------EHCVALKEAEVEGMASRIQEFEAILK
AKEAVIVQRDLEIDTIKKWKVTHSLELETVLLA-LTHFCHALEQ--------QTLATP--
EEPPELQQLRMQCARLSHQLQVLHQRFLSCQVELDQQQTQVASVGC--------------
----SSP------CA------D--------------------------------------
--------TQLE------QDSVSTG-LAL---------------------------VPHS
S---PP----------------------QAKEKH-PEACQLGSATLIAQVKQLQEKLNHL
LHSMAFRDTSMENPKLPQ-----PNLSENGSS--NNC-----------------------
-HNDEEDSVSPPVDGFNIAKTT---------------------WDLI-------------
------------QSQDLLTQS-EMPSFPPQETLTLQGGPLSSQI----------------
-----------------------------SVHTDP--LHTEE-AKPHKDPVRALDLSSWS
SPEVLRKDS-SLEPQHS---LPLTPHTDTVSLHSVDTSSQGWTDS-LLLA-DASGLLCYP
GRSA---ARQAPLWVLA------------------------PSAENRHVERPAAEKDVED
FIVTSFDSQELLTSL----------HELARRSD-GSGKSNGPSSALMLTLGSGGSE----
---------TPTTSLATA--DALPLSGRFVHSPGAMKEK-EIHAKHMKALLQMVFDESHQ
ILALSENQDLPNSLSKGE---------------PLDGLPRDRQALLEVTA----------
DRREKESLETHLTWSQELLRAIQEVFA--REQE--NAGLQSRPYG-LDLGDYNALFKRLE
KVIQERGD----LQ-KVQEHLCLPDRHSLLSEVQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIANDLQETLSKEQ
EKASDVRKLLMVEQSAVQDLKLELHACKQENTRLLESLDKVQQEVLRLRYGHALG-----
------------ALGLRPMLDGKENELRV-------------ALEELECE----------
--RGKERALQAQQEEQQL---------------------RHLQREGQSSRALE-ELKMSL
EKQRAQN--NQLCVALKHERAA-KDNLQKELQIES----------SRCEALLAQEKGQ--
-LYELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNAQEACAR--QEA-----
-QVQHALLRKLKAEKARALELEGMLEKVQRQAA---------------------------
---------------------------------------------QAQKQLESQAQ----
----ERCVELRKEKERELELQRQRDEHKIEQLQRM---VRELRWKEKVPGGDGPCWSAPS
----LG---------SP---EPNHVQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMHTLEELKSELSMPTSS----KKKMAAELQV-QLMNELLR-DNDALTK
AVGIATREKAELCRTVSRLE---KT--LKHHTQKG--------------CLLNR-QSKSS
WKQDGTVLQSSPRHPDPEWHTP---------TASVEAS-SCNTKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKL--TTSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALIH-CRSTR--QGH-----RMSRRQHSP---------
-----------SETRTSLPTREVSSGHIKDSRH-----------------------SPRS
SAAVSLGKEERSTSSPNSRLERSLAASQDAEHSLTEYIHHLEMIQQRLGGLPPD--S-T-
QKSCHQKIKQ--------

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-----------MDEDEQEERRRKVEAGRAKLASFRQRKTKSDCPNSKKKTAK--------
------RKGSAVNAPVQEED--SVATP-NSELPQ-GEA--GFESTSCS-------STLEG
STGEFA----AQERQD-----------------CDLDEP---------------------
------------------------------------------------------------
-----------------------------------------------------GL-----
------------------------------------------------------------
------------------------QPQPQQ--QLQPQ-----------------------
--------------------------------------------------QQPHLELEAL
RLSLNNMHTVQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELMREQH
AREKEE----VALRCGQEAAELKEKLRSEME-KNVQMIETLKQDWESEREL---------
---------------CLENLRKELSAKHRSEMEGLQNQFQREL--------AEQRAELEK
IFQAKHEAEVS-LK--ETQHQAAVKKLQEDLQSEHCQYLQDLEMKFREKEKEKE----LE
LENLQASYEDLKAQSQEEIRRLWSQLE-----SVKTNTEGLN-GEEFCGLFRSLEVKLCE
--------DP--------PC-KR--P----------------------------------
----IGP-PLLQVM-------RSAA----CVLVRMTPG--AGFR----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------GEKQFYLVEDHQVKLSK
AEEKIQLMKEEFHKKEAEWERSQEDLRRDAEGRLTSMFLELREKAESEKQSIISRFELRE
SGMRHLQEQQAA------------------------------------------------
---QILDLERSLMEQQGRLRQLEQELTRDEVL---PCSRCGQEPLA------AQDEEHIT
LLREKEDCALQLMMAQNRFLEE----------------------RKELMEKFAKEQDAFL
RDAQEKHAHEL----Q----LLQQGHQQQLQALRIELETQHHSELAEQLASLESKQQALV
ESHVAELQVKHNAEISTLQMKHLADLHAVESFYLTDIETIRDEHRKALELLRAELEEQLQ
KKDSSHNEILTHELEKLKLKHAEELQSAKDSSRIKMPA--KYTEEAKGLAT---DLQGTQ
QEELAVTVHN---QRHLLGKDGNAALGS---------------VGAKVLL----H-----
------------------------------------------------------------
----------------------------PTVPQELG-----------DPHTAEMQKPQ--
----AELVKPQELPASQEQAALVS-QVF-SLSREVEECRAELERLQQRRERENQEGATLI
CMLRADADLARSEGSVLQDALRRLLDLFGETLKTAVTLKSRISERAGLLLDHVDATDT--
-SDAR---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVCEISSHVCESFFMSPDNTLECEQPIRKVYQSLSRAVDGLLEMALDSSKQLEE
ARQLHCCVEKEFRHRNEEMAQSVQKQQELLEHLRQESAAKDGLALELHTAEGLLEGLKVE
KADLQEALGKKEESEQQLILELESLRKQLQQAA------QELATLREENSVLSSQKETLT
NEAKERE------------AALQKEVESLSRDQWEARKQSEKDRATLLSQMRVLESELED
QLVQHRGCGQLTEE-VATLKQELAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEE
QLRQA--ARPRPPGPRDSQ------VG---QPVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEEEI-------RRLEEKNVNIQRQMAQLQEELEKQKKNLEEL-KDNEVLKQEHTRD
LLLPPVSQ-RRLHEAGCPVPFQDSF-SRGPETQPEVTESTPVQPVH--------------
------------------------------------------------------------
-----------------------------------EVVPRRNSEIEELKAIIENLQENQE
QLQKDKAEEIEQLHEVIEKLQSELILMGPKLHELSDHQGSSLH----TELSCLHAEGQH-
-----------------------GQALRNELEAAQAAKEVFGQLLAEQAHGHSQALEELQ
QRLQDAEEVAARRLAEL-----------------EHCVALREAEAEGMASRIQEFEALLK
AKEAIIVQRDLEIDAINRWKMTHSLELETILLA-LTHFRHALEQ--------QTLATP--
DEPPELQQLRTQCARLSQQLQVLHQRFLRCQMEPDQQQAPVAPADC--------------
----SYL------CA------D--------------------------------------
----------LA------QDSVSME-LAL---------------------------APHS
S---AP----------------------QAKEQR-LEDCQLGSGNLVVQVKQLQEKLHRL
VHSMASRDTSLENPKLQR-----PSLSENGSS--R-------------------------
-HNDEESNASPPV-----AKTT---------------------WDVI-------------
--D-------AIKNQDLLAQV-EMPSFPPQELLTPQGGPL--------------------
-----------------------------GVHSDS--LHTEE-AEPQKDPVRALDLSSWS
SPEVLRKDS-TLEPQHS---FSLTPRTGTVSLRSVDTSSQDWTDS-LLPA-DAAGLLCYP
GKSA---TAQSPLWVVA------------------------PSAEDHRVERPATEKDVKD
FIVTSFDSQELLTSP----------HELARRSD-GSGKSDGPSSGMMPTSGSGGSE----
---------TPPTGPVAA--AALPFSRRFVQSPGAMKEK-EIHAKHMKALLQMVFDESHQ
ILALSESHDLPNPLSKGE------------PRDPLDGLARDRQALLEVTA----------
DRGEKEPSEAHLAWSVELLRAIQEVFT--REQE--NTELQSRSYG-LDLGDYNALFRRLE
KVIQEQGD----LQ-KVQGHLCLPERSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
TESRGSQREHQLRRQVELLAYKV-------------------EQEKCIANDLQKTLNKEQ
EKASDARKLLMVEQSAVQDLKSELHACKQENTRLLESLDKVQQEVLRLRYGHG-------
----------------EAMLDGKENELKV-------------ILEELECE----------
--RGKERALQAQQEEQHL---------------------RHLQREGQSSRALE-ELKMTL
EKQRAQN--NQLCIALKHERVA-KDNLQKELQIES----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNAQEACAR--QET-----
-QVQHALLRKLKAEKARALELESMLEKVQKQAA---------------------------
---------------------------------------------HTQQQLESQAQ----
----ERCVELRKEKERELELQRQRDEHKIEQLQRV---VRELRWKEKVPGGDGPCRSSPR
----LS---------SL---EPDRVQEQQQELERIRQQLLCAAGLLTGFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSIPTSS----KKKMAAELQV-QLMNELLR-DNDALTK
AVSMATQEKAELCRTVSRLE---KT--LKHHTQKG--------------CLLSR-QSKSS
CKQDGSVLQSPLRHSDPEWHTT---------ATSMEAN-TCNTKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKM--STSRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRRGALIH-GRSTR--QGH-----RMSRRQHSP---------
-----------SETRASLPTREVSSGHIKDSRH-----------------------SLRS
SAIVPLGKAERSTSSPNSRLERSLSASQDPEHSLTEYIHHLEMIQQRLGGLPAD--S-T-
QKSCHQKIKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAK--------
------RKGSAVDAPVQEES--PVAKE-DSALRG-GGD--ICKSVSCD-------DTSDG
AGGAFA----AQAEDCDGEKREDLEQLQQ----------------KQV---NDHQPEQR-
-GMFTVSD----------------------------------------------------
---------------HQPEQ-HGIFTMSDD-RLEQRG------MFTV-SDHQPERC--EI
FTMSDDRPEQRGMFTVSDH--------------QPERCGIFTMSD----------DRPEQ
HGMF--------T--------VS-D--------HQPEQRE-----II-TKACE-QECELA
ITDLESGREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVK---------------------
------------------------------EMEDLQNQFHKEL--------AEQRAELEK
IFQDKNQAEWA-LRNLESHHQATIEKLREDLQSEHGRCLEDLEFKFKESEKEKQ----LE
--------------------------------------------LHEELLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDSVE-------VGLS----CVGLEEKPE--KGRKDHIDELE---------
----PEQHKERLPCFQAELEESHRHQLEALESPVCIQH---EGHVSDRCCAE------TS
ALGHGW---C---LEPS--EGHSQELPWVHLQGVQDEDLEANTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKEDLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKAMKEELQREAEEKLTLMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQDLTSDDAL---HCSQCGREPPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHAREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLR
KKDCLHQTILTQELEKLKRKHDGELQSVRDRLRTEAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GTHQGEFGSEKKTALHEKEETLQLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEVLQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGEMLRAAITLRSRIGERVGLCLDDAG---A--
-GLAP---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESTAKAELALELHKTQGTLEGFKVE
TADLKEVLAGKEDSEHRLVLELESLRQQLQQAA------QEQVALREECTRLWSWGEAAA
TDAEVREA------------ALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--ARLQPWGPRDSQ------QTPLNGEVELLQQKLREKLDEFNELAIQKESADRQ
VLMQEEEI-------KRLEEMNINIRKKVAQLQEEVEKQKNIVKELEQDKEVLKKQQMSS
LLLVSTLQ-STLDAGRCPEPPSGSL-PEGPEVQLEVTQSALLQRESEVLDLKEQLEKMKG
DLESKKEEILHLNLKLDM-QNSQTAISLRELQEENTSLK---------------------
------------------------------------VVYTRSSEIEELKATIESLQENQK
RLQKEKAEEIEQLHEVIEKLQHELSVMGPVVHEVSDSQAGSLQSEL----LCSQA-RG--
---------------------PRGQALQGELEAVLEAKEALSRLLADKERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSTALREAEVKGMASRIQEFEAALK
AKEAMIAERNLEIDALNQRKVAHSAELEAVLLA-LACIRRALEQ--------QPLAAG--
AEPPELQQLRAQCGRLSRQLQVLHQRFLRCRVELDRRQASRATVHTR----------VPG
AHPQPRVDGGAKAQVAGDVEA-------SCDAALE--P--VVPDPQ-------GDLQPV-
-LVTLKDAPLCK------QEGIMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDGG
----------------------------KGEEKV-LEDCQLPKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAANTKSPWPLAS-AHPLESSWS--DDS-----------------------
-CDGEEPDISPTIDTCDANTATGGVTDVIRNQAIDACDANTAMGGVT-------------
--D-------VIKNWDSLIPD-EMPESPIQEKSECQDRSLSSPT----------------
-----------------------------SVLGGPHHQSHTAEAGSRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLGDRADTSLPQT-QGPGLLCSP
GVSA---AALAPRWAESPP-----------------------ADD-HHVQRTAVEKDVED
FITTSFDSQETLSSP---------PPGLEGKTD-RSEKSDGSGFGARLSPGSGGPE----
---------AQPAGPVT----PAPVSGRFQPLPEAMK-K-GVHPKHVKALLQMVRDESHQ
ILALSEGLVPPS----GE------------PRPPRKEDEVQDGSLHGG-K----------
TQ---EVPTTCPDWRGDLLQVVQEAFE--KEQE-----LQPRHSG-SDPGDHSSLLERLE
KIIREQGD----LQEKSPEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQTVVRDLKSDLCESRQKNEQLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------TLQELETE----------
--QGKGRVLQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLRVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQKACVH--QDT-----
-QAHHALLRKLKEEKSRVVDLQVMLEKVQQQALHSQQQLEAEAQ-KHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKAAWSQAELEQSHPRLKEQEGRKAARRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSCLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLSAARLLTSFASQAVDRTVND
WTSSSEKAVMSLLHTLEELKSDLSRPISS----QKKMAAELQF-QFVDVLLK-DNVSLTK
ALSTVTQEKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSR-SERSA
WKPDETAPQSSLRRPDPGPLPP---------AASAEAH-TSSVKMEKLYLRYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFSRFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAAR--P-----GPRARR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHRL
AAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPD--STS-
KKSCHQMIKQ--------

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-----------------------------QLAHFRQRKTKGDCAYPKKKTAK--------
------RKGPAVDAPVQEES--PVATED-GGLLGRGGD--VCRDTSCS-------DTPDG
AGAAQA----SR---GQNMLPEDQSQLEILQVDLILTYSDQQVAIYSNS-----------
------------------------------------------------------------
---------------HIKVQYHGLFLVVTF-SPQVNI------YYS--------YK--DR
VAEGLHGKCSRSSH-----LPSQF--PSWQLTEKWQKA---------------------A
FDLP--------V--------MC-QEQRK----MRHLSSKPVTSREFFLQDRE-QDCKLE
IAQPMGRQEDEAGAQ---------------------------------QQPVPSLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELRAMLNGRHAQELALLRSRQQQELELAREQH
AREQEE----MRLRCSQETAKLKEKLQSEME-RNARAVESLKRDWESERGL---------
---------------CLENLRRELSAKHRSELENLQDQFKREL--------SEQKAELEK
IFQAKNQAECA-LRTLEAQHEEALRQLREDLQSERCQYVQDLELRLRDQEVEKQ----LE
LESLRASYAELKAQSQEEIRRLWSQLE-----SPRPDRQDAS-A-------RTPHGEELE
QRERECGVQ---------QQRRGRRAEQESELGQS-------PEGAAERGREDPVLLEQR
LQDATEEPSLESGG-------IGYG----SPFHLKFRPACVKGRDESNVLDPACSPSKST
PTLRAELAENHRCH-LTAWTS----SLEAQ---------------QQAGLVE------TQ
ESEG-------EQREG-LSEGPGQELTQVPVPCAQGTALKVDTEVVARGLG-LEAEHRLK
LLLLQTE------LKEEMDVLKLENRNLH-EKLQHEVCLKEDLERVKHSLVEDHREELKK
ANERLQLVKQELKDKEAEWKVASEDLKRKAEEELTLMLHDLKEQAEAEKQSVINKFELRE
IKMRQLQDQQAA------------------------------------------------
---QILDLEGSLVEQQGRLRQLEHGLEAEECP---RCGHCGQEPAGRV--APADQDWELA
TRRLREDCALQLMQAQSRFLKE----------------------RKELTEKFTAEQDALL
QEAQEKHACDM----R----LLQERHQQHVLSLTAQLEARRRAEVEELKASVESERWALA
EARVAELQTEHAAAISALEARHSALLGSLESRHLSEVQAMREEHRQALEQLRVDLEKQLQ
EKEASHPTPLTQALEKHPLSHGQELPPVEGGLRTQTSS--GQLEGVKAPV--PPEV----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAQQGEFESEKKVALHEK-EIHGLECAQAQSL
YQKEKESLF-LQLQEKNNQILQLKEQIL-SLSHEVEERRRDLEQLQQRRERENQEGTNLI
SMLKSDADLSDRERRALRDALRRLLSLFGEMLKVAIALKSRISERVGLCLEDEDPPGAWP
SGQAL---------SAAPVLEETWPGSEAAL------LELDRSLPECV------------
---EMPSEAEISSHICESFFMSPESSLEYEQPIRRIYQSLGLAVEGLLELALDSTRQLEE
ARQIHSRFEKEFSCKNEETAQVVRKQQQLLERLEEENAARTRLMLELHQAQGIIEGFKEE
KASLQEALCRQETAEHGLAEELEGLRQQLQQAA------QQQAELKEENSALWSQKEASA
AEAEAREA------------ALRREVECLTQEQSEARKQSEKDRAALLSQMKVFEAELEE
QLSRHEACAKQAEE-LSALRQQMAALDKHLRSQRQFMDEQAVEREHEREEFQREIQRLEE
QLRQA--ARPRPHGPRVSD------EEQLDEEVELLQEKLREKSDGFNELVIKKELADRQ
VMIQEEEI-------RRLEETNASCRREAAQLREELERQRDAMKALQQDKEALQEKQMSN
LLLVSTLQ-SKLDEGRCPVPPADSC-PEGPEVQLEAVQRALQQRESEVLDLKEQLGKMKD
DLVSKSDEVLHLNLELDA-QSSRAAVSVRELQEENASLK---------------------
------------------------------------VTYDRSSEIEELRSIIENLRENQQ
RLQKEKAEEMEQLHEVIERLQEELSLGAPAVPAAVDCELPAVP--------------A--
---------------------------PAVGPEALAAAGAASRLFAEQEHRHGQALEALQ
QRLQAAEEAAAGQLAEL-----------------ERSAALREAEVQAMASQIQAFEAALR
AKEARLAERDLEIDAMKRQKLAHSAELETILAA-FSRFRRTLER--------QPLAAE--
DEPPELQRLRVQCVRLSRQLQVLNQRFLRCQKEADKQQARGARLRPR----------GAR
GLQGPGPRAEEASRDEASQQDV-DSRQVASATQGQ--VRDPQNAVN-------DDLQPAE
LPVTSGPPGLLK------QDSVMSV-LAVCQRQLESEL--LLLKN-----EMHLRTEDRG
----------------------------KNKENL-LEDRQLQKVGLISQVKELQEKLNHL
VRSVNFQNIETEDFKSQQPVAC-SRALENSLS--DSS-----------------------
-SNGEETDRSSLVDAFHIDKTT---------------------CDLN-------------
--D-------LSGNQDPLMRN-EMLDVPVEDKVELQEGPRCLQA----------------
-----------------------------NFHGGSPDLTPTEGPGPLKNALRAMDLSSWS
SPEVVRKDL-TLEPVPS---LPLTPCSDALS---LDASLQDRTSA-SLQA-DQLELLWYL
GQSP---AEKASRSAESPL-----------------AADRVPSAD-HHVLQMAVEKDVED
FIVTSLDAQEKPRSS---------PLGFEGKSN-GSENSDGSACGEILNQDLGRLG----
---------APAARPPG----PPAASGRFRRPLEAMKEK-EVHPKQVKALLQMVCDESHH
ILALSECRGLPSALSREG------------RAGTG----RVGGAVGG-------------
-GGSQEPPDPGLDWRGEFLQAVQEAFG--KEREMLRAELQPRPCG-SAPGEHSSLLERLE
KVVQEQGR----LQEKSLEHLRASDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEARGSRQEHQLRRQVELLAYKV-------------------EQEKRIASDVQKTLTEEQ
EKASSVRKLLVVEQTVVRDLRSELRECKQDNERLLASLGEAQKEVLQLR-----------
-----------------SVLDSKESNLRA-------------ALQELESE----------
--RGKERALQSRLEEAQL---------------------QHLQREGQSSKTLE-ELRASL
EKQFAQS--SQLCVALKHEQTA-KDNLQKELQIEA----------SRCEALLAQERGQ--
-LSELQRSLEAEK-GRSLEL------AAALRHERLLTEQLSRGPRE--------S-----
-PAHHALLRKLKEEKSRAAELQARLEQVQRQ-------QEADVQ-KRRAELEREKEVRAA
QAR------EPG---RCLR--REGHASQQQAGLEPLQAGLAAQEGRKDARRA-DVGPGRA
DA--EMRPTGAKEKLRELELQRQRDEHKIRQLQRT---VQALEAKEEA------------
-------------AQRP---EAERLQEERLGLERVRQQLLCAAGLLTSFISRTVDRTISD
WTSSNEKAVTSLLHTLEELKSELSTPSSS----QKKMTAELQT-QLVDVLLK-DNDSLTK
ALRTVTQEKAELCRAVSQLE---KS--LKHHVLRR--------------GVCSK-PDRCA
GKQDGTALPSSARQPDPGLPPA---------AAREDAN-TCGVQMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKT--TTSRPFTRFRTAVRVV
IAILRL--RFLVKKWQEVDRRGAATH-GRAPR--PEGLP----A-PRQQPP---------
-----------PAASRSPPTRDTSCSRSGDRA----------------------------
-PKASPGRRHRSTPSPDSRSQGSPAASQDPERSLTEYIHHLEVIQQRLGGAAAD--SGS-
KKSCCQRMKQ--------

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-----------MEEDEQEQRRRKVEAGRATLAHFRQRKTKGDCVHSKKKTAK--------
------RKGPPVDAPVQEES--PLVTQ-DGGLLQ-GSG--ACRSTAGS-------DSPDR
ARGAFA----TQE-----------------------------------------------
------------------------------------------------------------
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---------------------------------------------------------QDQ
DCESMGIPEDKAGQQQ----------------------------Q---PQAAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQSELELVREQH
AREKEA----MALRCGQEMAELKEKLQSEVD-KNAQMIETLKQDWESEREL---------
---------------CLENLRKELSARHQSEMEDLQNQFQKEL--------AEQRAELEK
VFQDKTEAEVS-LKSLEAQHQAAVRKVREDLQLEHCQYLENLELKFREKEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLE-----SAKTSREEMH-EPWPPPLAGVLHMEQLE
HLRQEFAQQ---------QQQDR--AQHESELEQLRLYFENKLRDAEKTYQEDLSLFQQR
LQEAKEDSLPGSVE-------ISSS----CAFLEDTSD--REGKEHPDQLNLQ-------
----LEQQEGSVACLQPGPKEKHR-LGSDLCSSLHVLR---EEDESDRGL----------
--VGPE-VLEWEPFRAVLSDQHSQEPAQVQPQCMQDTAVEMDAQVTARVLG-LEAEHKLK
LSLLQTE------LKEEIELLKMENRNLR-EKLQHETRLRGHLESVKFSLVEDHQAELNK
AEEKIKLLKQEFKKKEAEWEITHEDLKREAEEKVTSMLLELQEKAELEKQSIISRFELRE
AEMKSLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLRQLEQGLAGYDAL---LCSRCGREPPVAQ-HG-----GHPI
PL-REEDCALQLILAQNRFLEE----------------------RKEIVEKFAEEQDAFL
RDAQEKHAQEL----Q----LLQQRHQQRLLSLRTELESKHQAELAELMATLESEQQVLL
ETRVAELQMKHAAEISALETRHLSNLDALESCYLSEMHTVRDEHRRALELLQTDLEEQLR
KKDSFHQVILTQELEKLKQKHDAELQSAKDSLRTEMST--IHAEQLEVLAR---ELQGTH
QGKFESEQKA---A---VSEEEVHRLEHES---------------VPGL-SQEQD-----
------------------------------------------------------------
------------------------------------------------------------
---------LPPL-QEDSQTQQLKGQVL-SLSREIEECRTELERLQQRRERENQEGATLI
SMLRADVDLSQGERRALHDALRRLLGLFGETLKAAVALKSRIGERVGFLLDHTGTTAA--
-DQAL---------STAPALEEVWSDDAAL-------LELDRTLPEGA------------
---EMSSLADISSHVCESFFMSPESTLECEQPIRRVYQSLSMAVDGLLEMAVDSSRQVEE
ARQLHSHFEKEFSHKNEETAQVVQKHQQLLECLQAEGAAKAALALELHTAEGLLEGLRVE
KADLQEALARKEASEQQLVLELESLGQQLQQAA------KEQAGLREEHSLLWSQKEAQA
VEAEARAAGTRVT-AAHRDSALQKEVESLTREQLEARRQAEKDRAALLSQMQILESELED
QLRQHQGCARQAEQ-AATLKQQLAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQKLEG
QLRQA--ARLRPPGPHDQ--QQYV---WLDEKVELLREKLREKSDGYNELVIKKELADRQ
VLIQEEEI-------KRLEEINAHTREQMALLQKELEKQKEMVKEL-QDKEALTEPQTSE
LMPAPMSQ-PGPDEGRCPVLPLGSL-CEDPEGWPEAVQRVFLQDG---------------
------------------------------------------------------------
----------------------------------DEVVYHRSSEVEELKSIIENLQENQE
RLQKDKAEEIEQLHEVIEKLQAELTLLGPVVHELSDRQADSLHS----ELLCFQAEGPGG
Q------------------------ALQGELEAALVAKETLAQLLADQAHGHSQALEGLQ
QRLQAAEEAATRQLAEH-----------------GHNMALREAEVKGMTSRIQEFEAVLK
EKEAVIVQRDLEIEAMNKQKEAHFIKLEAVLSA-LARFRHALEQ--------QPPASS--
-EPPELQWLRAQCVCLSRQLQMLNQRFLGCQVDLDKQQARGVPE----------------
THPHPHVDTKSADLLEQGGGS----------KLLA--SDPHGRGSQ-------DDPQPAK
VLAMLKDAEFHK------PESVVSV-LTVCQRQLEAEL--LMVKN-----EMCLSMEDDP
RAPGKR----------------------KGKEKW-MEDGHLQKVDLIAQVQQLQEKLNCL
AHSVALQDMDPIGSRFQQPSAL-TYLSENS------S-----------------------
-HGRAEADTLPPVHSLNSDETT---------------------WDLT-------------
--D-------TTKNQDALSRN-EMPNSLIQEKIEPQDGRLSLQT----------------
-----------------------------SMHDG---SLHAEEAEPLKDPGRVQELSSWS
SPEVFRKDS-SLEYWPSI---PLTPCSGAVSLRNAEASPQDP--SWLLQS-SL-------
GGS---TEEQTPLWT---------------------ATLPS---D-QPVGRIAAEKDVED
YIATSFDSRDVLRSP---------PPGLEGRSD-ESEKSDGLGCGVRLNLGSRGPA----
---------TPTTGAVTPAP----VSRGFQQPPGVVQAK-EIHTRHVKALLQMVCDESHQ
ILALSESRDLPSTLSKGE------------PCTPLTCFPSEGQGLLEVAP----------
KKGEKELLDSRFDWRAEFLEATQ-MFE--KEQNMVQAELQPRPCV-SDPWGHSLLCRKLE
KVAQEQGD----PQEKPWEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEARSSRQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLSEEQ
ERARGVRQLLAVEQSAVQDLQSELRECQQENARLLESLGEAQHEVLQLR-----------
-----------------SLLDGKESDLKA-------------ALEELEQE----------
--RGKERALQARQEEEQL---------------------RHLQREGQSTKALE-ELKVSL
EKQFTEN--NQLCVALKHEQTV-RDNLQQELQIEH----------SRCEALLAQERGR--
-LSELQRSLEAEK-NHAREL------SEALQHERLLTEQLSRGAQHPQA-----------
---HHAMLRKLKAEKARVLELQVALQVAQQQVLQAQQQLEAQVQ-EHYTELGRE------
------------------------------------------------------------
-------------KEQELELQRQRNEHKIEQLQQT---VRELQSKE--EVPLGSGPFLDS
----------------L---ELSSIWEQQQGLEKIRQQLLCVAGLLTSFVNRTMDRTLND
WTLPSEKAVSSLVQTLQGLKSELSMSASSQK--K--MAAELQV-QLVDVLLR-DNDSLTK
AISTVTQEKAELCKAMSRLE---KT--LRHHVQKGC--------------ILSR-SSRPA
WRQDRTVSQSWPQHPDSGRPTL---------AASEEAN-TCNIKVEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSRADKKM--STSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGASLLQGKAPH--PG-----PRVPRKQLSL---------
-----------LETRESPPTQDVPSHHARDSA----------------------------
--CRSPSGRERSSPSPSSRLERPLTASQDPEHSLTEYIHHLEMIQQRLGGAPPD--STS-
KKSYRQKIKQ--------

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-----------MEEDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKKTAK--------
------RKGAVVDAPVQEEN--PVAAED-GGLPQ-GGD--VWRSTSCS-------STPDR
AEGEFA----AQACQERRPLTLLKS------TGQLFCIAPINLGLFPDYTQIVHF-----
-------SVLL-------------------------------------------------
----------RYGHSIHSLLVKGVSSGHSW-GRLP-------------------VA--GW
RQDDTRLTRCLRHLIRMLGDDDGE--RKEELENL--------------------------
---------------------------------VQKLDESCPEQTGITTKECE-QGHELE
IASLNSRHKDELDRLR----------------------------A---ELTVHSLELEAL
RLSLNNMHTAQLELTQTNLQKEKETALTELREMLNGRRAQELALLQSRQQCELELLKEQH
TREKEE----MALKCGQETAELKEKLESEME-KNAQILETLKRDWELERDL---------
---------------CLENLRKELSEKHQSEMETLQNQFKNEL--------AEQKAELER
IFQAKNQTEST-LSSLETQHEAAIQKLREELQSEHCQYLEDMEVKFKEKEREKQ----LE
LESLQASYEELKAQSQEEIRRLWSQLD-----SSRTAVQDLN-VFQEQLLARAPHLEELE
HLKRDFQEQ---------QQREK--TAHETELEQLRIYFEKKLKDAERNYQEYLTLLQQR
LQEVKEDSFLASVE-------INSS----PALLEETSE--KERKDYLDQLKVQ-------
----LEQHKESLARLQVQLEEKHQREVKALMWQGEVGV---PSAVPSQGALA------EG
TIGA-------GRSR---HDSIPHALAQMRLQHKQDAAFKVETEVAARVLS-LENEHKVQ
LSLLRTE------LKEENESLKIENRNLR-EKLQHEIELKEDLERVNYNLVEDHQGELKK
TKEKIQLMKQEFKEKEDEWKVTNVHLKRKAEEKLAQMLLELREKAEFEKQSIINKFELRE
TEMRRLQDQQAA------------------------------------------------
---QIQDLEKSLVEQQGRLRQLELGLPGEEPL---RCGHCGQEPGVE--AAPAAQGWALG
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RELQERHNHEL----W----QTQEDHQQHTASLVAELRTKHQAEVDELRTALASEQRALL
ETRTAELQTRHAAEISALETRHLSNLDSLESCYQSEIQTIRDEHRQALEHLRVDLEEQLQ
KKDSFHQMILTQELEKLKLKHDEELQCTKDSLKIEMST--KHMDSLK-AM--AAEL----
------------------------------------------------------Q-----
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----------------------------RAHQSEFERTEKAALHEKEVLLKLEREKAQVL
FQEENAALS-LQLQGKSSQAQQLKDQIL-SLSNEIRECHSELEELQQRRERENQEATNLI
SLLKSDLALSRSERKALQDALRRLLSLFGETLTAALAVKSRISARVGLCLDADGGA----
VGTAS---------QPAYPLDETLPTFDVAP------LDLDQPWPEGS------------
---ETASVTDISSHVRESFFLSPETTLECEQPIRKIYQRLGVAVDSLLDMALGSTRQLEE
AREIHSRFEKEFNYKNEETAQVIKKQKELLESLEEESAAKAKLVLELHKAEGVLEGLKVE
NASLQGALGQKEESEERLVLELEKLRRQLQAAT------LEQAELREECSVLRNEKDTVA
AEAGEREA------------GLRKEVERLAEEQLETRRQSEKDRSALLAQLKVLESELED
QLRQHQGCARHAEE-VLALEQQLASLDKHLRHQRQFMDEQAAEREHERDEFQQEIRRLEE
QLRPA--ARPQPCGPQDHG------SIAPSEEVELLQEKLRQKSDGFNELVIKKELADRQ
LIIQEDEI-------KRLEETNADARRKVALLQEELEKQKKMEKESQQDTEALKAQQMSP
FILGVSGR-ESRTGSAGGAWPAGGC-E-RPTVFQDAFSLVCLNFKGKVLDLKEQLENMKD
NLVSKNEEILHLNLKLDT-QSNCTAASIRELQEENAALK---------------------
------------------------------------VIYNRSSEIEELKSIIENLQENQV
RLQKDRVEEIEQLHEVIEKLQKELSLAGPVIHEISDSQVENLQSELEKGLLCFGEAAA--
---------------------DPGL----LGPRVQALERELSAAF--------AAQESLR
QSLQATEEAAERQLAVL-----------------RGSVALRESEVESMASRIRAFEATLR
EKETAIAEKELEIDALSRQRASRLTELGTILPA-LSRWQRTLEQ--------QPLAAV--
HEPPELQALRVQCAHLTHQLQVLNQWFLQCQEQLDQCPAG-PPAPQRCAEPTSARRPMGG
AFGGHVFNAASPT-----------LSNPFKKNNVL--PLIPQCLVA-------DDLQPAK
GLVTLTDAGLQK------PERVMSV-LTACQKWLESEL--LFVKT-----EMPLSKEDSS
----------------------------KGKEKL-LEDGQLQKIDLITQMKQLQEKLNHL
VCSMTIQDMETEDFEFLHPSA---RPLENSSS--KTF-----------------------
-SNDEHTDGSLPADGFNVSQTT---------------------RNRP-------------
--E-------DLENRDPLMGN-EMSDFPIGNKAELQEGSLPLKT----------------
-----------------------------SLHSSSLDLNCSEVAEPFKIQARTMDLSSWG
SPEVVRRDS-SLQPPPS---LPLTPCSDAAG---LDSSLRGGAPPSLVLA-DESGLLCYS
GVSP---AEKACQWPEPQS-----------------------AGP-PHVERTPVEKDVED
FIITSFESQEHLRSP---------PRVLEGKND-GSEKSDGSGVEEILNQGSGAAE----
---------PPAA-PAV----APRSPGGRPLPPAAMRGK-DVHAKQVKALLQMVCDESHQ
ILALSEFRGPPSVLSGGE------------PSAPLGRFPGEHQGL-L-------------
-GTEQALRDRGLDWRGEFLQAVQDAFE--KEGAMLKVALQAQLCG-AEPGGRSSLLERLE
QAIRKQGD----LQEKSLEHLHLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTS
AEAHGSRQEHQLRRQVELLAYKL-------------------EQEKCIASNLQKTLNEEQ
EKAAAVGKLLVAEENAVKDLKSELREWKQEHERLLKSLSDTQKEVLQLR-----------
-----------------TALDSQEKDLRA-------------ALKELESE----------
--RGKQRALQSQLEEQQL---------------------QHQQREGQSSKTLE-ELRISL
EKQNTHS--NQLCVALKHEQTA-KDNLQKELQIEY----------SRCEALLAQERGK--
-LSELQKSLEAEK-SHSLEL------AEALQHERLLTEQLSRRAPEACLR--PET-----
-QRHHAAVRQLKEEKARAAGLQARLERAQQQALRSKQQLEAEVQ-VRCEDIRKEKEVSAK
RKSRVEALQTQEQELICDVERERERPARLQAELGQSQSRLKEHEAPTETRRRTETRQSHA
DAEEGTKWQRGKERLRELELQRQRDEHKIKQLQQT---VRDLEAKEAARHAAGLRMDAVC
----GSA--HTAPCLSP---EQDQLQQQQEELERIRQQLLRAAAFLTNFINQTVDRTIND
WTSSNEKAVTSLLRTLEELKSELSTSASS----QKKMAAELQI-QLVDVLLK-DNESLTK
ALGTVTQEKVEVCRAVAKLE---RT--LKLHLQKG--------------CALSR-SGRSA
WKQERMALQSSPRNADQGLPAA-----------GEEAA-AHSVKMEKLYLQYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKM--NASRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGTLMQ-GRALH--PGEGAPG--P-RRHHSP---------
-----------VKTRESPPTRDTYASLSRDPV----------------------------
-ATASARRKERSNPSPHSRSERSLNASQDPEHSLTEYIHHLEMIQQRLGGIPPV--RFLF
KNSCHQKIKQ--------

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---------------CLESLRKELSAKHQTEMEDLQNQFQKEL--------AEQKTELER
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LENLQASYEDLKAQSQDEIRRLWSQLD-----STRTNRQELS-ELHEQLLVRTSHVEELE
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AKEKIELMKQAIKKKEADWKVVREDLRREAEEKLTLMLLELREKAESEKHLIINKFELRE
TEMRHLQDQQAA------------------------------------------------
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MLQVKEDCALQLMMARNRFLEE----------------------RKEITEKFSAEQDAFL
REAQKKHAHEL----Q----LLQERQQERLLAVTTELEARHQAELGELAASLESERWTLL
DARVAELQTKHAAEISALETRHLSNLDSLESCYLSEIQTIRDEHRQALELLQADFEEQLQ
KKDSFHHIILTQELEKLMLKHDKELQSAKDSLRMEMST--EHVESLRALA---HKL----
------------------------------------------------------Q-----
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HPEEGASSS-LQLQEKNHQIQQLKDQVL-SLSHEIEACRSELEMLQQRRERENQEGANLI
SMLKADIDLSHGERSALQSILRRLLSLLGEILQAAIALKNRIGECVGLCLDDAG---A--
-GQAL---------SAAPTLEETWS--DAAT------LEQDQTLSGCA------------
---EMSSMADISSHIRESFLMSPESVLECEQPVRRVFQSLALAVDSLLEMALGSSKQLEE
ARQIHSRFEKEFSDKNEETAQVVRKHKELLECLKEESAAKAELTLQLHKTQGILEGFKVE
KADLQEALGCKEESEHQLVLELESLRQQLQEVT------QEQATLREEYARLWSQKEASA
MEMEERET------------ALRKEVEDLTQEQSETRKQAEKDRLSLLSQMKVLESELEE
QLSQHQWCAKQAEE-VTALKQQMASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--AKLQPHGHLDSQ------YTQLDGEIELLQQKLREKSDGFNELAIKKEIADRQ
VLIQEEEI-------KRLEEMNINTRAKVVQFQEELEKQKKIVKELQQDKEALKEQQMNN
LLLVSTLQ-SKLDEGRCPVLPLGSP-PKGSEVQLEATQRALLQCESEVLDLKGQLEKIED
DLVSKNEEILHLNLQLDI-QNKQTAVSLRELQEENANLK---------------------
------------------------------------VVYTRSSEIEELKALVENLQENQE
RLQKDKAEEIEQLHEVIEKLQRELALMGPAVHEVSNSRADSLHSEL----LSSQS-VG--
---------------------PRVQALQAELEAALAAQEALSRLLADRERGHSQALEALQ
QRLRGAEEAAAQQLAEL-----------------GRSTALREAETEGMASRIREFEAALK
AKEAVIAERDLEIDAMTQRTVAHCTELEGVLSA-LAHVRCTLEQ--------LPLATS--
DEPPELQRLRIQCIRLSRQLHVLNQHFLRCQLELDKQQACGAAAHMQ----------MP-
-----LREGCIEPRVPRDAEA-------TCDDMLQ--R--GDPDPR-------VGS----
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----------------------------KGKEKV-LEDCQLQKVNLIAQVKQLQEKLSHL
MYSVTFQDSDTTDVQVQQPLAL-AHVLESSSS--DSS-----------------------
-CDGEETDKLPPVGAFNIDKTT---------------------GDLV-------------
--D-------VTKNQNSLIRN-GIPHLPIQEESESQDEPWSSQT----------------
-----------------------------GVRSGSHGLSGAQEGETLKSPVRVLDLSFWS
SPEVLRKDS-TLEPRPS---LPLTPCSGALSLRSADTSPQDRRETSLLPP-DQLGSLCYP
GVSA---VSLVQQWAESLP-----------------------AVH-HREESTAMEKDVED
FIITSFESQETLSSP---------PLGLEGKNN-GHGKSDGSGFGVILSPGSGDPE----
---------APTAGRVA----PASISRRFQLLPEAMKEK-EVHPKHVQALLQMVCEESRQ
ILALSESHGPPS----E-------------PRTDLD---------C---K----------
VQNGLESSNMCLDWRGEFLQAIQEAFE--KERELLRVERQPRLGG-SDLGGHNSLLERLE
KVVQEQGD----LKEKSLEDLHLSDRSSLLFEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEAQGSRQEHQLRRQVELLAYKV-------------------EQEKCIASDLQRTLREEQ
EKASSVWKLLVAEQSTAKELRAELRECRQDNERLLQSLHDVQQEVVQLR-----------
-----------------SVLDGKENDLKA-------------TLEELESE----------
--RGRERALQSRLEEEQL---------------------RHLQREGQNAKSLE-ELRMSL
EKQRAQS--SRLCVALKHEQTT-KDNLQKELRIEH----------SRCEALLAQEQSQ--
-LSALQKDLEAEQ-SRSLEL------SEALQHERLLTEQLSRRTQEACAH--QDT-----
-QAHSALLRKLKEEKSRVADLQAALEKAERQAAHAQQQLEAEVR-RRCEELLKEKEVSAT
LKSTEEALQTQRQELRCSQERERERPARLQAELEQLHARFQEQEGPEDARRSMGTRQSPA
DGEPWPQWQRDKEMLRELELQRQRDDHKIKQLQQT---VRELEARNTAL-H---SDGSHR
----G-------AASAD----VDCLCKQQQELEEMRQRLLCAAGLLTSFLSQTLDRTIND
WTSSNEKVITSLLSMLEELKSELSRPNSS----QRKMATDLQI-QLVDVLLK-DNDSLTK
ALSIVSREKLELSRAMSKLE---KT--LKHHLQKG--------------CILSR-SDRSA
WKQDGAVLQSSPRHTDPGRLLL---------AAGEETN-TCHIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--IISRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAPR--PV-------RRRQQQSP---------
-----------PKTRESPPTRDVPSGHTRDPTL-----------------------GPGP
LHLSN-----STLF--SPSSERSLTVSQDPEQSLTEYIHHLEMIQQRLEGVPPD--STS-
KKSCYQKIKQ--------

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IAISR-------------------------------------------------------
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---------------------------------------------------LHSLELEAL
RLSLSNMHTAQLELTQANLCKEKETALVELREMLNDKRAQEVALVQSRQQFELEHIKEQH
RKEKED----MALEHQQELAALEKKLELEVEA-HSQTLEALKGDWDSEKGS---------
---------------CLRRLEEELAQKHQAEMESVREALRAQL--------AEQKAELEK
MAHDKAQAEAA-LSSLQAQHQAAMQDLRQELQLQRDQYLEDMDLKVREKQ--------QE
LDTLQASYEELQAQSREEIQQLWSQLD-----STRANRQELN-ELREQLLARASHVEQLE
HLKHDFERR---------QQQRR--SEHERELEQLRLYFEQKLRDAEDSYREDLHLLHQR
LQEVREDSFLDSAD-------VSWS----VEFMEDTAE--VERKAHLEQLMLQ-------
----LEQHKEGIAHLRLQLEEKHKEELDALKASLEVRHKQ--Q-----------SMAEMQ
REKRQH-DLDLEELRTRLTEEHRKEMIKVRLQCAQDTARQVEAEVAQRLSLALEDDHKAR
VAQLQS------QLTEEVGLAQKENEDLQ-EKLQREVALKEEAEKKSCGLVEDHQKEIKK
LREEIQQLIQRNKDKEDEWQVQRGDLSRRAEERLAALALELNGKAEREQRALREAAELRV
VEMERLRDQQAA------------------------------------------------
---DIMRLEESLRQREESRAQEE----------AAWQERAAQDLEAAK--AQMAKELEAA
MRSLREDCALELQTSQARFLEE----------------------QKEMTQKFTGKQEALF
KELQEKHAGELQLQT-----SLQSQHRAQLEARVANLQTQHREDMDALRTSLQSQYRVQL
EARVADLQTQHVAEMSHLEAKHLSNLDSLESGYLSEIQTMQEEHSHALEGLRVRLEEQLQ
AKEAEHKACLAQE----TEKHQRELQQAQESLRIEMTT--NHIEKLKSLAT---ELQDAH
QDTLE-------------------------------------------------------
------------------------------------------------------------
------------------------------------TEKRAAEEQAEELVALEREKAQGV
CQREKEALT-SQLQEQSSLILQLKEKIS-SLNNEVAESHRELEKLQALREREHEEETNLL
SLLQSDMSHTQQERKTLQETNQHLLSLFGDTLKAAIAIKNQISKRIGVCLDEDSLGRE--
--S------------T-----AMGRQEQPTQD-------------TCESQFDQTL-PEC-
-DETLLAETDISCHVRESFFLSPGVTMECEQPIRRIYQSLGVAVDNLLEMMLDSNKQLEE
TRELHARFEKEFNRKNEETAGAVRQQQELMDRLNQESAAKNQLALELHKAEGLAEGYKAE
KAALEESLLQKEKSEHHLAVELENLKAQFQALI------QEQARLKEEQSLLLRQKEKLV
VEAEEKA------------AGLLQEVEHLVKEQSETKQQSEKDCSTLRSQMRALELELEE
QLSHNQELVQQAAE-IQDLKEQIVSLDKHLRNQRQFMDEQAIEREHERDEFQQEIRKLEE
QLEQQQPAKSHPWGEPHDNQ-----PTNLFPHVESLQRKLREKIDELNELVIKKELTERE
LSAQKDEI-------RNLEDANEVIRRKVYWLEDELEKQKKIGKELKQDREALQEQQMNN
LIQISSLQ-SKLDEAKHLTPAQGSPNGDDLKEQLEAEQAALLLKEKQVLSLEEELEQLKD
KLTSKNNEILQLNLELAL-QNSQFNASIQELSAENTD-----------------------
----------------------------------LKVMDDRSSEIEELKAVIENLRENQE
RLRKEKLEEAEQLHEVIEKLQQELSLLGPVVHEVSDSQGDSDSS----QPENLQRELQKG
LFSFR---ATALDEGAREP---------------DPHVEQLRDALREKESQCQLRVEALE
RDLQSVRVASTERLGLL-----------------SHQLSLKEAEAKRVASQAQHWQ----
---AAFLEKEAEADALTEERGAFLAELRALASA-CSHLKRDLEG--------KRAWGS--
GEPPELQMLRTQCVGLNLKLQALSRKLVTYQVALDQHQACGPQCQVQIQKHLKGADAL-G
TH------G---ARAPRR--------------------LLSGAPA---HESLVEEAAFTP
KGLAIRKE---A--GIQRRESVISV-LTVCQKQLESEL--LFMKK-----RMPLSKEHGS
QLLGAL-------------------------KKP-MEGDQLHKGDLMTQVRHILEKLHRL
IKSISSVDRDAD---------GG---KQLLWDLADDAKSHASPGWGRRQFQFDQSPDSFP
SSPRGDPDYAEP---------------------------LTPE-SCYF------------
--E---------------------------ERVAASNVPGQVKSRDS---PPPDGGRFSR
EPSQESAQGSPWDG--S------------TENGSQVDTDALETVEHFRDTILDTDASSLG
SPELVRRDS-TLESLPSF---HLTPLSHTAGLQSPE----AAWR-SLALP-DSSGYLGLP
ALPGLAASPPAC-KDKSQPDA------------------------GQDLKSRILEKDVQD
IILTPKDLQEGRQSK---------TPGSEGDGL-G---DDISELGDKLKQDSYRSG----
---------PPPSRPV-AHLHKAQKSGMVQRPFKPMKDKLEMQSKQMKALLKMVCDESQQ
ILVLSEEGEAGPAGGRAGPQRAP----------LPGVVPSW-------------------
-GQVKEPSDPVFDWG-EFLQAVQEVLE--KERHVLKVELQSKLCN-LESGDERSLLEKLE
DVVKEQGE----LQKRTLENLHLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLYEALTN
VEDHGSKQEYQFRRQIELLEYKV-------------------EQEKGLVGDLQKTLTIEQ
EKGIETQKLLLAAQSAAQGLTAQMEECRRDKEAVSQSLRDAHKDIAHLRSV---------
-------------------LGSREEDLAS-------------ALDGLQAE----------
--KQKVAELQVLLEEERR---------------------QSVQKDELRSKAVE-ELQASL
EQQRSQN--GQLVVSLQHEQAE-KDNLKKELQIEY----------SRCEALLCQERSQ--
-VGELQRSLEAERAR-SAEL------GEALSHERLVTEQLSKRAGEASS----QKEAQLQ
HAFVRKLKE----EKARGAELQALLDEARRQGLAAQKQLELEVQ-MHCEEMKKEKEVSGR
LQASADALQKQKQELLCYVDEERAKQGRLQAELEQLQSRLKDEAGKEARRDKERRHEVQA
EEEKGKRGKKEKERLRELELQRQRDEHKIQQLQQT---ITELEKDKGFAVSRTWQEA---
G---------PGVALPPDAEK---LQEHQEPLENVRQQLLHALGLLTGFMNQTVNRTVSD
WTSLNEKAVTSLLLTLEELKSELMPGLPQK------KTTQAQI-SLIDVLLK-ENGSLTK
ALSTMTQEKVELCRTVSKLE---KT-L-KHHLQKGCGH--------------IK-ADKAT
WK-QQKMALPGSRHSEAGMVKAAFK------GESTHGGSTCRIRMEKLYLHFLRAERFRK
ALI-YQKRYLLLLIGGFQDSEQETLSMIAHLGVFPSKIDKRAF--PSRPFTKFRTAVRVV
IAILRL--RFLVKKWQELDRRATFVQ-SVPEE---AVEISRPQPPL-SSSPS-----LP-
------------ETTSSPPTQDLPLSSLKGRRS-------------------------PS
PACRL---WDSRSLTSPSSSADVYDSSQDPEHSLTEYIHHLEVIQQRLGGVQPA--ELTS
KKPAHQKPKK--------

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------------MEDEQEQRRRKVEAGRAKLANFRQRKTKGDGPNSKKKTAK--------
------RKGSAVHASVQEEG--SVAPP-NSELPQ-GAA--VSERESCG-------NTLEG
TGGAFA----AQEQQD-----------------CELGVT---------------------
------------------------------------------------------------
-----------------------------------------------------DL-----
------------------------------------------------------------
------------------------QGQQQ----PQQQP-QPPQ-----------------
--------------------------------------------------TAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELMREQH
AREKEE----MALRNEQETAELKEKFRSEME-KTVQMMETLKQDWESEREL---------
---------------CLETLRKELSAKHQSEMEGLQNQFQKEL--------SEQKAELEK
IFQAKHEAEVS-LKNLEAQHQAAIRKLQEDLRSEHCQYLQDLELRFREKEKAKE----LE
LETLQASYEDLKAQSQEEIRHLWSQLE-----SMKTNREEQN-GSWEPLLAQASHLEELQ
HLRSDFAQQQ--------QQ-ER--AQHESELEHLRVYFEKKLNDAEKTYQEDLTVFQQR
LQEAREE-SLESAE-------ISSS----CMFPEETSG--RERKEPPDPLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLEQPKAQGSLIEDYQEKLSN
AEEKIELMKQEFQKKEAEWELSREDLKRDAEEKLASMFLELREKAESEKLSIINRFELRE
SSMRHLQDQQAA------------------------------------------------
---QISDLERSLREQQGHLRQLEQELTRDEVL---LCSQCGKEPSV------AQDEKSAI
LLREKEDCALQLLTAQNRFLEE----------------------RKEIMEKFAKEQDAFL
LDTQEKHSHEL----Q----LLQQGHQQQLLALRMELETKHHSELTEQLASLESKQQALL
ETHVAKMQVKHDAEISALEKRHLSNLDELESCYVADIQTIRDEHKKALELLRAELEEQLQ
KKDSCHREILTQELEKLKLKHAEELQSVRNSLRVKMSA--QHTESGKGPAA---DLQGAH
QKAPAMALHN---EGHQLEEDGDAALGG---------------ADTEDLQ----H-----
------------------------------------------------------------
----------------------------HAEPRERE-----------GPHTVEMQTSQ--
----TELAKPQELQASQDQGAQVRDQVF-LLSRELEECRGELEQLQQRRERENQEGATLI
CMLRADVDLAQSEGKALRDALRRLLDLFGETLKAAVTLKSRISERAGLLLDHEDAVDT--
-SGAQ---------LAAAALGEMWPD--EGL------LDIDRTLPEGA------------
---ETSSVCEISSHVCESFFMSPENTQECEQPIRKVYQSLSTAVEGLLDMALDSSKQLED
ARQLHRCVEKEFRHRDEEMAQAVQKQQELLERLREESAAKDRLALELHTAEGLLEGFKVE
KADLQEALGKKEESEQQLIVELEDLRKQLQQAS------RELLTLKEENSVLWNQKETFT
NEAKEREAGTPVS-AGREDAALQKEVESLTRDQWESRKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLAEE-VTTLKQQLATLDKHLRSQRQFMDEQAAEREHEREEFQQEIKWLEG
QLRQA--TRPRPPGPRDSQ------CAKLDEEVELLQEKLREKLDGFNELVIKKDLADQQ
LLIQEEEI-------KHLEETNENIQRQMAQLQEELEKQRRSTEEL--------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------EVVNSRNSEIEELKAIIEHLQENQE
QLQKAKAEEIEQLHEVIEKLQSELSLMGPTVHEMSDLPPGSLH----TELSCLQAEGMG-
-----------------------GQALHNELQAAQAAKGAFGQLLAD--HGHSQALEALQ
ERLQDAEAAAARHLTEL-----------------EHCVALRQAEVEAMASRIQEFEATLK
AKEAIIVQRDLEIDAVNKWKVSHSVELEALLLA-LAHFQHAVEQ--------QTSATP--
DEPPKLQQLLVQCARLSHQLHVLYRRFLRCQVELGQHQPRVASVGC--------------
----ADP------PAEAQGKRD--------------------------------------
--------GELE------QDGVSSG-LAL---------------------------APHS
L---VA----------------------QAKEEQ-PEDCHLGNTSLRAQLRQLEEKLDPQ
AHSVAFRDTSMETCKLQQ-----PNPLENGSS--NHC-----------------------
-HNGEESRPSPPNDVP--AKTT---------------------WDVI-------------
--G-------VIKNQDLLAQI-EMPDSPTPEKLASQGGAFSSQA----------------
-----------------------------SVHGAS--LLPEE-AEPQKDPVRALDLSSWS
SPEVLRKEP-SLEPQHS---LPLTPGVGTVSLHSVDISSPDWTDP-LLQA-DVSGLLCYP
GKSA---TGQAPLWVVA------------------------PSAEKHHVERTATEKDVED
FIVTSFDSQESLTSP---------SHELARRSD-GSGKSDGPDIAAMLTLGSEGSE----
---------TPTTDLVAA--TTGPFSRRFVQSPGAMREK-EVHAKQMKALLQMVFDESHQ
ILALSESQDSSSALSKGE------------PRDPLDGVPRDRQALSEGTS----------
DRGEKEALGTHLTWSEELLQAIQEVFA--REQE--NAELQPRPYS-SDLGDYNSLVKKLE
KVIQEQGD----LQ-KVREHACLPDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIANDLQKTLSKEQ
EAASDVRKRLMVEQGAVQDLKSELHACKQENTNLLESLDKVQQEVLRLR-----------
-----------------AVLDGKENELKV-------------VLEELECE----------
--RGKGQVLQAQQEEQQL---------------------RHLQREGQSSRALE-ELKISL
EKQLAQN--NQLCVALKHERAA-KDNLQKELQIEA----------SRCEALLAQEKGQ--
-LSELRKSLEAER-SRSLEL------SEALQHERLLTEQLSRNAQEACAR--QDT-----
-QAQHALLRKLKAEKARALELEAMLEKVQKQAA---------------------------
---------------------------------------------HTQQQLEAQAQ----
----ERCLELRREKERELELQRQRDEHKIEQLQRL---VRELRWKEEAPGGNGPCRGSPC
----LG---------SL---ERDQFQEQQQELEKIRQQLLCAAGFLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSMPTSF----QKKMAAELQV-QLMNELLS-DNDALTK
AVGMATREKAELCKTVSRLE---KT--LKHHTQKG--------------CILNR-QSKTP
LKQDGMDLQSSLPHSDPEWHPQ---------TTGGDTN-TCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKV--TASRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALIHHSRSTR--HGH-----RTSQRQNSP---------
-----------SGTRASLPTRDVSSGHTKDSRH-----------------------SPKC
S-ATSLGK-GRSTSSTSSRLERSLTASQDPEQSLTEYIHLLEMTQQRLAGLPPD--A-P-
QKACPQKIKQ--------

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-EEECTAIHS---ERRLLEE-KEAALDS---------------VSAEVLP----------
------------------------------------------------------------
-------------------------------PERLR-----------EAPPAEVQKAR--
----VELAEPQELQASQAQAVQVSVSMFLSLSQEIEECRAELERLQQRRERENQEGATLI
RMLRADLDLSQSEGKALRNALRRLLGLFGETLKTAVTLKNQIGERMGLSLDHVDAADA--
-GQTP---------LAAPALDEMWSD--EAL------LELDRTLPEGA------------
---EMSSVAEISSHVCESFFMSPENTLECEQPIRRVYQSLSMAVEGLLDMALDSSKQLEE
ARQLHCQVEKEFHQKDEEMTQAVQKQQELLDLLREESAAKAELALELHTAEGLLEGFKVE
KADLQEALGRKEESEQQLVLELESLQRQLQQAA------QELATLREESSILWSQKETSA
NEAAARE------------AALQKEVESLTREHLEARKQSEKDHTALLSQMRVLESELED
QLSQHQGCAQLAEE-VTTLKQQLAALDKHLRSQRQFMDAQASEREHEREEFQQEIQRLEE
QLRQA--ARPRPAGAHDSQ------CAQLDEEVELLQEKLREKSDGFNELIIKKDLADQQ
LLIKEEEI-------KCLKEANANTQRKVAQLQEELEKQKKTTSES-KDKEALNEQQMSG
LLLVPVSQ-SRLSEDGCPMFLPGTI-SDGPEVQLEVVQRTLLQRES--------------
------------------------------------------------------------
-----------------------------------EVVYSRSSEIEELKSIIENLQENQE
RLQKDKAEEVEQLHEVIEKLQRELTLMGPIVHELSDHQAESLH----SELFCYQAEGLA-
-----------------------GQTLRTELEAALAAKEALGQLLADQAQGHSQALKALQ
QRLQTAEEAAARHLAEL-----------------ESCVAVREAEMKNMVSQIQEFEALLK
AKEAAIVQKDLEIDTMNKRKVAHSLELEVILLA-LAQFRYALEQ--------QPLATP--
DEPPELQQLRLQCARLSRQLQVLHQRFLRCQVELGQHQARGMPGCS--------------
----PHP------GTDA-------------------------------------------
------------------QGTVGRC-PAL---------------------------TSHT
Q---DP----------------------QAEEKG-AQGCQLPTVDLLAQVKVLQEKLRLV
VHAMASQDGSPEDPAFQQ-----PSAS---------L-----------------------
-CVAEETDPSPPVHAFN---------------------------SLI-------------
--D-------VTKNQDSLIQS-EMPGFPTQEKLVSQGGPLSSHT----------------
-----------------------------SVHTDS--LYTEE-AEPRKDPVRGLDLSSWS
SPEVLRKDL-TPEPQPSL--LPLTPSTGTLSLHSASTSPKDWRDS-LLGA-DLPELPCYP
DESA---AGQSPPRVVA------------------------SSALQHQVEETAVEKDVED
DIITSFDSQEQTRCL---------PLQLEGRND-RRGKSD----SAMLTLGSGEPK----
---------APTTGVT-----AAPIPRGAFQPPGAMKEK-EVHGKHMKALLQMVFDESHQ
ILALSESQDLPSALSKGE------------PREPLDGFPRERQVLLEA------------
APGEKVPLDTQLAWSRELLTAVQEVFS--RDQE--STGLQPRSCG-SDLGNDSSLFKRLE
KIIRDQGD----LQEKVQEDLGLPDRSSLLSEIQALRAQLRMTHLQSQEKLHQLCTALTS
AESRGSQREHQLRRQVELLAYKV-------------------EQEKCIASNLQKTLSKEQ
EKASEVQKHLVVEQSTVHDLKSELHESKQENAKLLESLKEAQQEVLQLS-----------
--------------GTGAMLDGKESELKV-------------ALKELECE----------
--RGKERALQAQQEEEQL---------------------RHLQKEGQSSRALE-ELKISL
EKQRAQN--NQLCVALKHERAA-KDNLQKELQIES----------SRCEALLAQEQNQ--
-LSELKKSLEAEK-SHSLEL------SEALRHERLLTEQLSRSAQEACAR--QET-----
-QVQHALLRKLKAEKARALELQAMVEKVQQQAA---------------------------
---------------------------------------------HAQQQLEAQAQ----
----KRFAELRREKERELELQRQRDGHKMEQLQRM---VSELQWKEEVPWRDSSGQGPPH
----PE---------SL---ELDRIRKQQQELEKIRQQLLCVAGLLTTFTSRTVDRTIND
WTSSNEKAVSSLMRTLEDLKSELSKPTSS----QKKIAAELQV-HLVDELMK-DNDSLTR
AVSTAAREKADLSRTVSRLE---KS--LKRHAQRG--------------CALSR-PGKSA
WKQDGTVLQSLPAHSDPEWPTA---------TANEEAN-TCNVKMEKLYLHCLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKT--TMSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRRGALVQ-GRAAR--PGH-----RVSRRHPSP---------
-----------PETRESLPTRDLSSGHSRNPGP-----------------------RPRP
AAAASLSRRERSPSLPNSRLERSLNTSEDPEHSLTEYIHHLEMIQQRLGGPPPD--S-P-
QKSCHQKIKP--------

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--------------MQ----------------------------Q---TEILHNLKLESL
RLSANNIHTSQLELMQSNLRKEKETALMELREMLKDRHAQELAVLQGQYHFELERIKEQN
YKEKEE----MALKHQHDLDNERKEITLKMEEKYVQMLEDLKKECALKADI---------
---------------TLKDMSEELLAKHAIELCEMKRTLE--------VEMEKLRGDLET
LHLQKEQGEME-HKKLENQYHLA----MKKLQVEHEQEVKEMTEQNKKQEKELQQEESWL
PTLQTAEIQKLQAESEEEIKQLWSQLD-----SARASRQELS-ELKEQLLARTSQMEEIE
CLKKDFQLK---------WDKKR--SEHEIELEQLRVYFEQKLKSVEENYREELTILHQR
MEEAKDYSLLEIEN-------SPST----TLL-EEMTE--KERRDIFDQLTQQ-------
----LEHHK-------IKIKLIGD-HTAALRR----------------------------
--NKEK-IQELELLHKAKAEEWKQE--------QEDLNIKNE-----------------M
LSLLHKD------LENK-----TQCEQQA-LQRQLELEK-------------------AE
MT----------------------------------------------------------
---S-LQDKQAA------------------------------------------------
---RIVELEKSLKEQQ-NNVQQLTDS---LTNAQKTLSQYDSELASSR-A-LMTEELEKA
KQVLQEEYNLKLKNAENRSI--EE-----SKAMT---------------EKIKSEHEVLL
QELRVKHVDELELKSK----ELYHKHKEEILSLTLKIQTKHQAEIEALKSALEAKQQTWV
ETYVTGLQNDHKAQIAELEAKHLSELNTLESTYLSEIQLLQDEQKQALEDLQMDLQKQLI
LKDKANQILLAQELDGMKRKYAGDLKVCQDNLKIELAT--IHIEKLRTMAE---ELEEAH
KEDLSIALEN---QRRLLEDDYHKSMDILQ---------------KEVLCIKEQHRNTIE
ELDSLHKLEVKKEK-EK-------------------------------------------
------------------------------------------------------------
-----WQQLQKDMEELNSVRQQLEEKKR-CLSKEIEDASTELQNLRRQQDRENQEGENLI
ALLKSDIELYKNEREKLQESYQQALKLLLKMMKSTKDAEDQICKKIGLCLDYSFASG---
-DSE----------ENQ----NMRARGDLLPILW---LHLR------SPILNIEKDSHDS
L--KPDELSELSEHLCESIFENPDLVFANEERVHQICHCLHLAVEKLLDLVAESTKQLEE
MYNVHLHVEEEFMRKNLEACQVANEHQELVGCLNEESNVKNQLMLELHKTKGLMDGYLAE
THALQEALKLKEESECRLVLELETLKSQIQELK------QKVGRSTEDRKFPISENKVLT
DS------------VGEREVDLIQEIEHLAKAKLEVQCQAEKDCSTLNAQIKMLEIELEE
QISKNQNLTVMSLE-VTDLRQQMQSLERQLKNQRDFMDKQAVEREHERDEFQEEIQKLEM
ELKLT--AKFQASGQSNLVSRMIPWGM---QWVDSLYSEIKEKTEDFNRLFLEKEQIQKD
LDAQKDQI-------KKLEAQ---------------------IRELELKNK---------
---EETNHAN----------------------QLTQELQKMKKMEAE-------LEQDKE
ALQQQNHN-------------NLI--QISALH---SKLDEVKHKLFTEWNT---------
--------------DDILNEQLKVQE-EL-ILRKREILESQALEIQNLKSVVECLHSDKE
QMLKDKTEETEQLRGIIEKLQKELELLTPTCQEANNSQNNINNF----AVVEQN------
----------------DINEIYNQNQLQGQLEAVLADREALQQLLEEKESQFKAETKIFK
QNLQDVLESSRQHFSKMSLAQKD-------------------MEMTKVNICIQELEDKLR
AKETDLLQKGLQLQSMLEQNSEQAVEAQQIKG-KVVQLENEQHTLLQALHLKPSIDKK--
REELEIQRT---------------------------------------------------
------------ERD----------------HFNS--QLKSN--ME-------KDQDNDK
LTF-------HGCLCRCIC----LPSSTV------SSLRILLGQPEQEGDKSPLSRAPSG
SAV-----------------------------LP-SSGCPRRGQRRVHGGGGG-------
------RR---------NGSHE-RC--GSGGN--TMRPQG--------------------
------------PGSASDNTEC---------------------WEKE-------------
--I-------ATSNLNAFSQYLNQQDKHLQSVFCVEEGKLI--NDDEKE-----------
--------QDPQPTFQQ---------RSQLSDLS--RNTQLMQKIPTNFQSMVMDETSWD
SPEILRKEN-SLELHP----GPFSDVGSSFL-GSEGLCSENSVIQGVTQGELEWPVSYS-
NGN--EEVGS-NVPESAYY-----------------HTQMSYLKSDVIMRQDS------R
FVVRSFVYVK----DNNSLLYKSNHELKRTLD---SLEKTKNTCSD---LVLQLNQE---
----ESKARVQQDSSVMTYLQCFGMVPD-ITEPTMKEKD-IFS-QQLKNVLKMVYEESYK
ILVLSEKSRPSYDKEHIQ-KSPSVERWQRERLEEQ--I----------ST----------
MKGNKENASSFFDWRGELLQAIQCVLE--KERLMFQNYLQLHFHN-PGSGNEGTLVLKLE
HIMDQQEQ----QQKAVLEHLLSSDRNSLLTEIQDLEAQLRLMHLQSQEKLQQLQEMLIN
TENHGSNQEHQLRRQVELLEYKL-------------------QQEKSIASDLQASLKSEQ
EKASEIHKLLKQQHTAIFDLKSDLCESKQVNEKLQKSLQELQKEVVKYS-----------
-----------------SDLESKENAITA-------------ILQDLQNE----------
--KLKEKELQNMLDDQQQ---------------------QNTLREDEKSKAIE-ELQAAL
ELQCIQN--NQLSVALEHEQSA-NSNLRKELQIEH----------SRCEALLSQEQNK--
-LLELQKNIEVEK-NRNLEL------LGALNHERLLTEQLSMKINECGSC--KHKGSLQE
------LQAQLYIERSHARELLSVIEKTRQHLD-SKKELD-N------------------
---------------MQMLVAQREKEAEMKREWEQLQLDLRSLRSQEN------------
--------------------------------------------------------RLVQ
LGPCKG--QDNNYTA-----DSIMLYVEQQKLENIREQLLCAATYLSEFISKTIDKTV-N
WPASNNEAVAALL-HILELKAELLA-SSKPM--KKKREKTDCE-IVNDLLSE-HNDHLLN
SIYIPGTSCSKLCLKRN-VL--SAF--YAFHLKDGKQQGGGKSPREFCTKSTPL-STSVW
WRSQESFLA---------------------------TS-FFKIQMQKLYKKYLRAESFRK
ALV-YQKKYLLLLLGGFQECEQATLSLIARMGIYPSLPDINASQSRSHLFIKFRSAVRVS
IAISRL--KFLVKKWHKVNRKNQQ-PTTISPS--T-------------------------
------------GYNSCDATQEAGYGS-RKDLVRLTNSSPKSQHLH---DSCSAQASSDD
FNFS-----------MSKRFSTSQASSKDPEKSLTEYIAHLEVIQQRLGFLMPV--STK-
RSPLNGLKA---------

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-----------MDKDEQEQRRRKVEAGRAKLANFRQRKTKGDGPHSKKKTAK--------
------RKSSAVNAPVPEES--PVATH-NSRLPG-GGI--VCKSKSCS-------DELEG
ARGASA----AQEQQV-----------------DELVET---------------------
------------------------------------------------------------
-----------------------------------------------------DQ-----
------------------------------------------------------------
------------------------Q---------EQLP-LPPS-----------------
-------------------------------------------------QTAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELVREQH
VREKEA----MVIRYGQETAELKEKLRSEME-KNMQMIETLKQDWESEREL---------
---------------CLENLRKELSAKHQSEMEGLQNQFQKEL--------AKQRDELEK
IFQAKQQAEVS-LKNLEAQHQVAIKKLQEDLQSEHCQYLEDLELKFREKEKEKE----LE
LENLQASYEDLKVQSQEEIRCLWSQLE-----SMRTKRGELN-GSWEPLLAQESHLDELE
HLRLDFAQQQ--------QQ-ER--ALHESELEHLRVYFEKKLKDAEKTYQEDLTLFQQR
LQEAREDSPLESAE-------TSSS----CVFPEETSV--RERKEQPDQLDF--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLEQPKVKRSLVEDYLEKLNK
AEEKIQLMKQEFKKKEAEWELSHKDLKREAEERLTSMLLELREKAESEKQTLINRFELRE
SGMRHLQDQQAA------------------------------------------------
---QILDLERSLMEQQGRLRQLEQELTGDESL---PCGQCGQEPLV------AQDGEHTL
LLREKEDYALQLMLARNRFLEE----------------------RKEIMEKFAKEQDTFL
RDAQEKHSCEL----Q----FLHQEHQQQLLSLRTELETKHQSELAEQRASLESKQQVLL
ETHVTELQVKHAAEISALEMRHLSNLDALESCYLADIQTIRDEHRRALELLRSELEEQLQ
KKNSTHKEFLTQELEKLKLKHDEELQSAKNSLRIEMSP--KHTQTLQALVT---HLQGAH
QKELATARHD---QR--LEEDRGTALDS---------------LGAKVCP----H-----
------------------------------------------------------------
----------------------------KAVLQELG-----------DPQTPEEQKPR--
----KELAKPQELQASQEQAAQVS-QVL-SLSQEIEECRAELERLQQRRERENQEGTTLI
CMLRTDVDLSQSEGKALRDALRRLLGLFGETLKTAVTLKSRISERVGLLLDRVGAADT--
-SQTP---------VAAPASDDMWSD--NTL------LEVDRTLPEGA------------
---EMSSVSEISSHVCESFFMSPESTLECEQPIRRVYQSLGMAVNGLLEMALDSSKQLEE
ARQLHCRVEKEFRHKNEEMAQTLQKQQELLEHLMEENTAKAELALELHTAEGLLEGFKVE
KADLQEALGQKEESEQQLVLELENLRQQLQQAA------QELVTLREENSILWNQKETFT
NEAEARE------------AALRKEVESLTRDQWETKKQSEKDRATLLSQMHILESELEE
QLLQHQGCGKLAEE-VTTLKQQLAALDKHLRSQRQFMDEQAAEREHERDEFQQEIQRLEG
QLRQT--SRPRPPGPHDSQ------CAQLDEAMELLEEKLRERLDGFNELVIKKDFADQQ
LLIQEEEI-------KRLEETNVNIQRQMAQLQEELEKQKKTVKEL-QDEEALKGQQMSD
LLLTPISQ-PKLDETGGPMLSQDSS-FRGPEAQLDVTQRTLLHPEN--------------
------------------------------------------------------------
-----------------------------------EAVYSRSSEIEELKAIIENLQENQE
QLQKDKTEEIEQLHEVIEKLQSELTRIGPVVHELSDHRPGSLH----NELYCFQAESLG-
-----------------------GQALQNELEAALAAKDALGQLLTNQAHGHNQALEALQ
QRLQDAEEAAAQRLAEL-----------------EHCVALREAEVEGMASRIQEFEAVLK
TKEAIIMQRDLEIDTMNKKKVAHSLELEAILLA-LVRFRHALEQ--------QTVATP--
NEPPELQQLRVQCVRLSRQLQVLHQRFLTCQMELDQQQALFVPGGC--------------
----PYP------CA------D--------------------------------------
--------IQLQ------QGTVSRG-QTL---------------------------TPNG
Q---CP----------------------Q--EKQ-PEACQLHSVNLIAQVKQLQEKMNHL
VHSMSFQDTNTEDLKFQQ-----PNLSENVLS--NCS-----------------------
-HNAEETDLLPPVNVFNIAQTT---------------------WDVI-------------
--D-------VTENQDSLIQN-ETPDFPTQAKLTSQHGTLSSQT----------------
-----------------------------SVHSGS--LYTEK-AEPQKDPMRALDLSSWS
SPEVLRKDS-AFEPQPS---LSLTPCTGTVSLHSADTSPQDWTDS-LLRA-DTSGLLCYP
GKS----TGQDPLWVVA------------------------PSVEYCHVERTAVEKDVED
FIISSFDSQEPLRSP---------PPEIEGRSD-GSRKSDDPGIGAVLTLDSGGPE----
---------APTARLKAA--TAAPVSGGFVHPPGAMKDKEEVHAKHMKTLLQMVLDEGRQ
ILALSESQDLPSTLSKGE------------PRDPLDGFPRDRQAPLEVTT----------
DRGEKEPSDMHLTCSEEVLWAIQEVFA--REQE--NAELQPRPCG-SDVGNYSSLFKRLE
KVIQEQGD----LQ-KAQEQLCLPDRHSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
AEAHGSQREHQLRKQVELLAYKV-------------------EQEKCIASDLQKTLNKEQ
EKASDVRKRLVVEQSALQNLKSELQECKQENTRLLESLNKVQQEVLRLRYGHWKL-----
-----HNG-TGSAVTGRSMLDGKENELKV-------------ALEELECE----------
--RGKERALQAQQEEEQL---------------------RHLQREGQSSRALE-ELKISL
EKLRAQN--NQLCVALKHERVT-KDNLQKELQIES----------SRCEALLAQEQSQ--
-LSELQRSLEAEK-NRSLEL------SEALQHERLLTEQLSRNAQEACVR--QET-----
-QVQHALLRKLKAEKAHALELQAMLEKMQQQAA---------------------------
---------------------------------------------HAQQQLEAQAQ----
----ERCVELRRDKERELELQCQRDEHKIEQLQRK---VRELRWKEEVPWSDVPCRGSPR
----LA---------SL---EVDRVREQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAMLSLMRTLEELKSELSMPTSS----QKKMAAELQV-QLVDELLR-DNDSLTK
AVSTAAREKTELCRAMSRLE---KT--LKYHTQKG--------------CNLSR-PGKSA
WKQDMTVLNSSPQHSDPGWCTP---------TTSGEAN-TCNIKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TTSRPFTKFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALAQ-SRSTR--PGR-----RVPRRQQSP---------
------------ETRASLPTPDLPSGYIKDSQH-----------------------SPRS
AAAVSLSKAERSTSSPNSRLERSLTASHDPEHSLTEYIHHLEMIQQRLAGVPPG--K-K-
TVFLIVLVKVIGNWRASS

------------------------------------------------------------
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-----------MEEDEQEQRRKKVEAGRAKLAHFRQRKTKGDCAHSKKKTAK--------
------RKGPAVDAPVQEES--SLVTQ-DGGLLD-GGD--ICKSSACS-------NSPDG
PGGTFA----AQE-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------QDQ
DCELVGTPKDKAGQ-Q----------------------------Q---PQAAHSLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQNRQQCELELVREQH
AREKEA----MAFRYGQEMAELKEKLQSELE-KNAQMIETLKQDWESEREL---------
---------------CLENLRKELSARHQSEMEDLQNQFQKEL--------VEQRAELEK
VFQGKTQAEAS-LKSLEAQHQAAVRKVREELQLEHCQYLENLELKFREKEKEKQ----LE
LENLQASYEDLKAQSQEEIRNLWSQLE-----STRTKREELH-ELQQPPPAGVLHLEELE
HLRQEFAQQ---------QQRDR--AQHESVLEQLRLYFENKLRDAEKTYQEDLSLFQQR
LQEAREDPLLGSVE-------ISSS----CAFLEDTSD--REVKEHPDRPDLQ-------
----LEQEEASVVCLQAGLEENHR-PGSELCSSFCVQH---EEDESDRDH----------
--MRLK-VVDLGELRAAVSDQHSQEIAWVQPQCTQDKAVEVEAQVTARVLG-LEAEHKVK
LSLLQTE------LKEEIELLKIENRHLR-EKLQHESRLRGDLESVKFSLVEDHQEELNK
TEEKIQLLKQEFKKKEAEWQISREALKREAEEKVTSMLLELREKADLEKRSIVSRFELRE
AEMKKLQDQQAA------------------------------------------------
---QILDLERSLTEQQGHLRQLEQGLAGDDAA---LCSRCGQEPSAAQ-HG-----EHTM
PL-PDECCALQLMLAQNRFLEE----------------------RKEIVEKFAAEQDAFL
QDAQEKHAREL----Q----LLQQRHQQRLLSLRTELESKHQAELAELMATLQSEHQVLL
ETRVAELQMKHAAEISALETRHLSNLDALESCYLSEMQTVRNEHRRALELLRADLEEQLR
LKDSSHQVILTQELEKLKQKHNIELQSAKDSLRTEMST--IHAKQLAALDR---KLQGAH
QDAVESEQQA---A---VREAEVRSLELEP---------------AQRL-SQEQS-----
------------------------------------------------------------
------------------------------------------------------------
---------PSQL-QEDSQVQQLKDQVL-SLSQEVEECRAELERLQQRRERENQEGATLI
SMLRADMDLSQGERRALHDALRRLLGLFGETLKAAVALKGRISEHVGLLLDHTGTTAA--
-DQAP---------S--TALEEVWSDDVAL-------LELDRTLPEGA------------
---EMSSLEDISSHVCESFFMSPESTLECEQPIRRVYQSLSMAVDGLLEMALDSSRQLEE
ARQLHSRFEKEFSHKNEEMAQVVQKHQELLECLRAEDTAKATLTLELHTAEGLLEGLKVE
KAGLQEALTQKEASEKQLVLDLESLGRQLQQAA------EEQAVLREEHALLKSQKEAQA
VEAEAR------------EAALQKEVETLTREQSEARRQSEKDRAALLSHMRVLESELED
QLVQHQGCARQVEE-AATLKQQLAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEE
QLRQA--TRLRPPSPHDS--QQCL---QLDEEVELLQEKLREKSDGYNELVLKKELADRR
VLIQEEEI-------KRLEEINAHTRGQVALLQEELEKQKNVVKKL-QDKEALTEPQMSD
LLHVPTLQ-SRPIEGRYPVLLLGS----HPEAQPEVVQRALLQDE---------------
------------------------------------------------------------
----------------------------------NEVVYHRSSEVEELKSIIENLQENQE
RLQKDKAEEIEQLHEVIEKLQGELALLGPVVHELSDHQADSLRS----ELLCFQAEGPGG
Q------------------------ALRGELEAALSAKEALAQLLADQAHGHSKALEALQ
QRLRAAEEAAAQQLAEL-----------------EHNMALREAEVEGMTSRIQEFEAVLK
AKETIIEQRDLEIDAMNKRKEAHFAELEAVLLA-VAHFRRTLEQ--------QPPASP--
-EPPELQRLRAQCVRLSRQLQVLNQWFLRCQVELDKQQACGVPE----------------
THPHLPVDTESGNLLEQGGRS----------KRLA--STSRGRGPQ-------GDLQPAK
VLVTLKDADLQK------PESVMSV-LTVCQRQLEAEL--LLVKS-----EMRLSMEDDT
RAPGRM----------------------KGKGKW-MEDCRLRKVDLIAQVQQLQEKLNCL
AHSMAFQDIDLVGSGFQQPSAL-TYLPENSSN--ASS-----------------------
-HGRAEADILPPVDSLNSDKST---------------------WDLT-------------
--D-------VIKNQDSLIGN-EMPNSPTQEKIEPKDGCLSLQI----------------
-----------------------------SVHGG---SLHAEEAEPLKDPGKVLDLSSWS
SPEVLRKDS-SLEPRPSI---PLTPFSGAVSLCSAEASPKDPI-PWLLQS-NL-------
GGS---PGEQTPLWT---------------------ATLPS---DHQPVERMAAEKDVED
FTITSFDSQDMLRSP---------PPGLEGRND-ESEKSDGPGYGAMLNLGSGRPA----
---------APTAGPVTAPP----ISRGFLQPPGVMQ-E-EVHTKHVKALLQMVCDESHQ
ILALSESRDLPSTLSKGE------------PYAALACFPGEGQGLLEVAP----------
EKE-KEPLDSSLSWKGEFLQATQEIFA--REQKMVQAELQPRPCG-SDPGDHSSPCKKLE
KVTQEQGD----LQEKAWEHLSLPDRSSLLLEIQALRAQLRMTHLQNQEKLQQLYAALTS
AEARSSRREHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLNEEQ
ERARGVRQLLAVEQSTVQDLQSELRECQQENTRLLESLGEAQREVLQLR-----------
-----------------SLLDGKESDLKA-------------ALEDLEHE----------
--RGKERTLQAQQEEEQL---------------------RHLQKEGQSSKALE-ELKVSL
EKQFAQN--NQLCVALKHERTV-RGNLQQELQIEQ----------SRCEALLAQERGR--
-LSELQRSLEAEK-SHALEL------SEALQHERLLTEQLSRGAQQPQA-----------
---HHALLRKLKAEKARVLELQATLQVTQQQALQAQQQLEAQVQ-ERCAELGRE------
------------------------------------------------------------
-------------KERELELQRQRDEHKIEQLQQM---VRELQSKV--EVPSGSGPHLDS
----------------L---ELANVWEQRQGLEKTRQQLLCVAGLLTSLVSRTMDRTLND
WTLSSEKAVSSLVQTLQGLKSELSMSTSSQK--K--MAAELQV-QLVDVLLR-DNDSLTE
AISTVTQEKAELCRAVSRLE---KT--LRHHVQKGC--------------TLSR-SGRPA
WKQDGTISQRSPGHSDSGRPTL---------AASEEAY-TCNIKMEKLYLRYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI---TSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDQKRAPLLQGKAPH--PG-----PRVPQKQLSP---------
-----------LETREFPPTQAGPSHRRKDSA----------------------------
--RHIPSRRERSTPSPSSRLERSLNASQDPERSLTEYIHHLEMIQQRLGGTPPD--PTS-
KKSCRQKIKQ--------

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------------MEAQQEQRRRKVEAGRAKLAHFRQRKTKGDGAHSEKKTAK--------
------RKGSAVNAPVQEES--PVAKD-DSEVRG-GGD--IYKSPSCD-------DSPDG
TGGAFA----AQLEDCDGEKREDLEQLHH----------------HSRWWDIDHHPEQRG
RGVITVSD----------------------------------------------------
---------------HHPEQ-RGVITLLDH-HPGQPG------VITL-------------
---SDHHPGQPGVITLSDHHPEQRGVITKVFFNSWAHHDGFL------------------
-VTV--------F--------SC-E--------FWIISFA-----F-FPQEYE-QECELA
IADMESRREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTTQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELDLLREQH
AREKEE----VALRCGQEAAELKEKLQSEME-KNAQIIKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMKDLQNQFQKEL--------AEQKVELEK
IFQDKNQAEWA-LRNLESQHQVAIEKLREDLQSEHCRYLEDLELKFKENEKEKQ----LE
LENLQASYEDLKVQSQEEIRHLWSQLD-----STRTSRQELS-ELHEQLLARTSHVEDLE
QLK----------------QA-K--IQHESELEHLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGAREDALLDSVE-------VGSS----CMGFEETPE--KERKDHLDKLE---------
----PEQYKESLPCFQVELEESHGHQLEALESALCIQQ---EGHVSDRCHAE------AA
VLGQAW---R---QEPS--EGHSQELPWVHLQ---DGAVEADTEVAARVLG-LETEHKVK
LSLLHTE------LKEEIELLKIENRNLH-EKLQREIRLKEDLEKVKHSLVEDHQEELDN
AMQKIQLMKQEFKKKEVDWKVTREELQREAEEKLTLMLLELREKAESEKQSIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLMEQQGRLQQLEQELTADEAL---RCSHCGREPPA-------VQSGELA
ALRVKEDCALQLMLARSRFLEE----------------------RKEITKKFSADQDAFL
REAQEQHAREL----Q----LLEEKHQQQLVSVTAELEARHQAALGELTASLENKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLQ
KKDSLHRTILTQELDKLKQKHDGELQSVRDGLRAQTSP--EL---TRTVA---HQL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKATLPEKEETHRLQSAQAQPF
HQEEKESLS-LQLQEKNHQVQQLKDQVF-SLSHEIEECRAELEALQQRRERENQEGANLL
SMLKADADLSYSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---T--
-GLAL---------SAAPALEETWS--DAAL------PELDRTLSECA------------
---EMSCVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
AVDLQKALAGKEDSEHRLVLELESLRQQLQHAV------QEQAALREECARLWSQGEAAA
ADAEAREA------------ALRKEVEDLVTEQSENKKQAEKDRSALLAQMKILELELEE
QLSQHLGCAKQAEA-VTALEQQVASLDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEG
QLHQA--AKPQPCGPHDSQ------QAPLDGEVELLQQKLREKSDGFNELALQKELADRQ
VSMQEDEI-------KHLEEMNVHIRKKVAQLQEELENQRNIVKELEQDKEALKEQQMSS
LLLVSTLQ-STLDAGRCPEPPAGSP-PQSPETPLEVTQSALLQRESEVLDLKEQLEKIKG
DLVSKNEEILHLNLKLDM-QNNQTAFSLRELQEENASLK---------------------
------------------------------------VTYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQQELSLMGPVLHEVSHSQAGSLQSEL----LCSQA-GG--
---------------------PGGQALQGKLEAALEAKEAVSRLLAEQELGHSQALQALQ
RRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALR
AKEVMIAERDLEIHALNQRKAAHSAELEAVLSA-LARLRRTLEQ--------QPLTAL--
AEPPELQLLRAQCARLGRQLQVLHQRFLRCRVELDKQQACNAAAHTG----------VPG
VHPQPCADG--------DVEA-------AHDAALE--P--AVPNPR-------GDLQPV-
-LVTLKDAPLCK------QEGMMSV-LSICQRQLQSEL--LLVKN-----EMRLSLEDGG
----------------------------KSQEKV-PEDCQLPKGNLIAQVKHLQEKLNCL
LDSMTLQDVDTADMKSPWPVAS-AHLLESRWS--DGS-----------------------
-HDGEEPDKSAPVDVCDANTAT---------------------GELT-------------
--D-------VIKRQDSLVPD-EVPDSPIQEKSECQDRPCSSPT----------------
-----------------------------SLLGGPHQQGRAMEARPWKGPVRMLDLSSWS
SPEVLRKDS-TLEPQPS---LPLTPHSGALSLCSADTSPRDRVDASLLQA-QGPGLLCYP
SVSS-AAALLAPKWARSPP-----------------------G-D-HHVERLAVEKVVED
FIT-SFDPQETLSSS---------PPGLEGKTD-GSEKSDGSGFGARLSPGSGGLE----
---------AHTAGPVT----PAPVSGRFQPLPEAMKEK-EIHPKHMKALLQMVCDESHQ
ILALSEGLTPS-----GE------------PHPAWKANEVPDGSLCGG-R----------
TQFYFDLPTTCPDWSGEFLQVMQEAFE--KEQEMQGVELQLQLGG-SDPGGRSSVLERLE
KVIPEQGY----LQEKSLEHLCLLDRSGLLSEIQALRAQLRVTHLQNQEKLQHLHMALTS
AEACGSQQEHQLRRQVELLTYKV-------------------EQEKSIAGDLQKTLREEE
DKANGLQKFLAAEQSAVRDLKSELCECRQESERLSGSLHEVQQEVLQLR-----------
-----------------SVLSSKENELKA-------------MRQELESE----------
--QGKGHALQSQLEEEQL---------------------RHLQREGQNAKALE-ELRASL
ETQRAQS--SRLCVALKHEQVA-KDNLQKELRIEH----------SRCEALLAQERTQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVQ--QDT-----
-QAHHTLLRKLREEKSRVVDLQAMLEKVQQQAVRSQQQLEAEAQ-KHCEELRREKEVSAT
LKATVEALHTPERELICFLERDREKPAWLQAELEQSHPRSKEQEARKAASRSAEAGQSPA
AMEQWRKWQTDKEKLRELELQRQRDLHKIKQLQQM---VRDLESKDEAP-GGRLHPDSAH
----G-------AATSD----VDHLQEQQRELEAMRQRLLCAAGLLTSFASQAVGRTIND
WTSSNEKAVASLLHTLEELKSELSRPTSS----QVRGEHPQVPNQMAWDLL---------
------------HWLLSLLE---FF--LRRALFCL--------------PGCSR-PDRSA
WKPDETVPESSLRRPDPGRLPP---------AASGEAN-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGAMAQ-GRAPR--P-----GPRARRLQQSP---------
-----------PRTRESPPTRDVPLGHARDPAR-----------------------GRGL
AGAASLQSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLSPR---------
WKSCHQKIKQ--------

------------------------------------------------------------
------------------------------------------------------------
--SELDAKMCQTKIAELEDRLLEKQEAVERLTAQMDELQEQLTQQRDSMQLQ---ETTVQ
ERNEVIRKLTSCLQQAKKDRNDLQEEASHVADQIHDLQLQLHQLLVNEMLKSKSPGKKEV
LEAQQQMSLFQNQFKEQNIRLEMLRQRAHDLEVQLESSQKVKLLEVLLNTKDKENLLVLM
EEGTKDTIQQLYESIGEKEQHIRSLQDLLTSERFNLSVLQHTLSLRDSEITELKNEITLS
KMKEQQCTEELKMNHEKDICKQLENLRVELEKCHRKEIAETKQIYEEEMILKYKNDLEQL
KKELSALNSEEHNQNLNSIIIDLNNSLHESEIHKENLRKKLENQQEKFQREKTEIEVQYK
ILIDVFKTRLSEAEEQVKEAQQYKQEKQHLNEEIQELDSCIHGLHKKPLFEAENSADARQ
EYNEEIVSNKNLMILKEKHTLPDASLSAALVLEEMMNKPCQFKGEEEFVPEELEFQCELG
VDSSRGESKEIMS-----SRIEESEGNEGDYLSEEQLSEPAFFTVDEDMLAKYLV--STE
RPEQ---SYLSGSSEDGSL-----QQNKINNSDVV-------KDDERASHICLLNQLTEQ
-----LHEKESA-LEKSQRETQEAAGKWKKVIAELSLLHKTEKEKELENKISHL-----I
KQQGENGGQPYHAVE-----PVTQTSESSTWQQMLKDLQEEREVLMVQLRTQEQLVKEVQ
EQKTASDSVTSEVQSLFGRQLAVLQ-SQRDQMQTQLDAQKAKNLTITELLGQKAVLEETL
LKEQDLLK-----AEI-----------SNKEQNLALLLKEKTVL---CERLSSMEKDLIK
AENALAANASIIADLEKNICELNTEVQNLKEESFQSAQAVQEAQSEMVKHYKEEMDKMES
QHLVELTKVSLTH-----KK--EVGNT-NNGSFG-IEE--LNN--E--------------
--------------IKDKV---EKQ-----------Q-----------------------
------------------------------------------------------------
--------------------------------------------------K--L-E---E
E--R-K---E-Q------------------L-A-L-I-------K------------K-V
-N-E-K----------------E-G-S-----L------------------------MKS
DASINGLKKKRQNSHF----------------------------S---CQTLHSLELEAL
RLSLNNMHTSQLELTQSNLRKEKETALVELREMLNDKRAQEVAILQSRHQLEWEKIKEQC
LKEKED----LKSKYQQELEDQYSLFTFWCC-NLIGMYFTYISACRLKKENRNGNGRETY
PDIRGEVEGKQLNVFALKNVCKELSEKHQTEMAELQKALE--------MELEKVKVELGH
VSLEKEQSEFI-------------------------------------------------
----------------TEHNQLLED-------------------I---------KMKSQE
KEQNLQKEQ---------RQQRK--NEHETELEQLRLYFEQKLRVAEENYREELTFLQQR
LEELKEYSLSEEAV-------MSQD----Q------------AGGI-RYPSQC-------
----------------LSKKIMSN-SQ---------------------------------
------------L--------------------SRKYNLKNS------------------
----------------------TNN-EKH-LKRE--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MEQQLEDSLASAQAIQKSQEQYESDLQAAK-V-LMEEEMQKA
MLCLQEECALKLTEAQNNLGGKET-----FRTYK---------------WKFTTEQEILL
QELKKKHVDELELQSQ----QLQEKHKQQILSLTTEFQTKHQAEKSKHQIQ---------
----------IEASVAELQTKHQAQIDELESSYLSEIQNIRDEHKQVLEKLQLHHTEQFR
EKDKMDQAHLAQEIERLKLKYAEELQLAQNNLKIELAT--VHMEKRESKRK---------
---LSIE--------------------VI-----------------QSMCMELEE-----
E---LGKLKAQHEH-E--------------------------------------------
------------------------------------------------------------
---------------------------------------QEVRELRIPEPKSVEE-----
KSDDYPCSMYFCSRKKMQESYQHILKLLMELVKAAIAIEDLICSKIGLCLDDSLASG---
-DSR----------ESH----SIMEEMGFAQYFK---AKEKHHLEKLDELLDETLTEHNQ
LSPVTEEGSELSQHLCESVFVKPEMAYENEEMIMKISHRLRTAVEKLLELVVESTKELEK
RHEIHVQFEDELSRQNQETAQVVSQHQELMECLTEESEAKNQLALELHKAEGIIEGYVAE
KAALEEALNLKEESERRLVVELEHMRERFQELT------QEQAILGEECKFGSLNKEV-F
KF------------LSTQWAGLLKEVELLAKEKLELQCQAEKDHSNLRSQMKVLEVELEE
QLHSNQNLAKQLLE-VAELKQQIQVLEKQLKKQRQFMDEQAIEREHERDDFQQEIQKLEE
QLKLT--AKLQTSGELRK------Y------GVDSLQAEIKEKMDDYNKLLLENEEKHQE
IIARDKEI-------EKLVAQ---------------------VQELEQSKL---------
---FCPDGFSKLDEARHRVPTEGTS-DQGLKEQLQAEQEALERKEGEIASLLEQLDQYKD
KLTSKNEEILQLNLQLEL-QKNLSTSSISQLQLENACLKEDLTKLHVKQNQDLRISDTLA
LSFPEAILKEKNQEIDHLNEQMKRLK HELENTLENTVVENQKSEIEELRSLIEHLRSDQE
RLRKDKDEEVEQLHGVIEKLQKELAQFGPVCHEVSDNQSDVYQL----GLEKSAEDLQNE
LKGLTDFQGDTDADRRNALLITNVRELQEKLELVSTAREALQQQ LEDKESQLKMEVEILE
KKCQNAQESSKQHLAELTSLRIQYNALQEEYSLFQKCASQREVEARITTSRIQELEETLK
EREASILEKDTQMKIMTDQREADKNELQYLTK-QAAELETELKK----KDANQAQDVY--
--SLQLQV----------------------------------------------------
------------SRL----------------DFQV--QTLNQ--KE-------AANQREI
NEL-------RGSTAKLKD----QIKAYV------KELEAL-----------QLERDE--
--L-----------------------------I-----------------SQL-------
------KL---------FKSKE-QC--NNEDA--NFLKEK--------------------
------------DEV------M---------------------FDSM-------------
-----------THNTNIKSQI-----KQSQEDISNQETDMM--NRSEEK-----------
--------QNLKKHYCTVLKFLLMLQKSSFVLLASCKVYVMFLFLPFYYRKVSKDRDS-S
TAGLRKMRE-ADNLTP----SD---LGDDIR-S-RGSAT--DV----MSN--EYGSSTSS
NLA--AKLKQELQPSDHLD-----------------ASFMAYMQYRGMFSE---------
-VMES---MR----EK--------EVLSPQLK---DNTGDVPACGRT-DLLIAFLLEVFS
ILIPDAEKQLGLIQKLSHAEKCKGLCTNNISQNNQSELD-LFPEKVFKTVLKMVYEESCK
ILALSEHSFGFKEQKNIHQTTAMMEGWRKEGIALLEAIQSLKDYLSKVAD----------
RGNKQEHSDITADWRAEFLQAVQSVFE--KERNVLQIDLKSHFSS-PGCGDEVSLAERLE
YIMKQQEE----QRQMVVEHLFSSDRNSLLSEIQDLRAQLPDKKPV--------------
---LAEEEDKSVKSKVELLEYKL-------------------QQEKSIVSDLHSSLSEER
KRVSETCELLNQEKAEVSALKSELYEHKQENERLQKSLEEHQREINKFR-----------
-----------------FELENKEKDLTA-------------ALQELQTE----------
--RLRETELRGLLEEQHF---------------------QHKKTEDENKKALE-DLQAAL
ELQSVQN--SQLSVSLEHEQMI-NDNLRKELQIEH----------SRCEALVSQEQKK--
-VSELQRNLEAEK-NRSLEL------LNSLNHERVLTEQLSMRAKEDASC--QHRASLLE
QAFIRELQAKLEEERSRTTELTAILDKTHQKAVHSNRQLEDEVR-MRCKETQKEREVSNQ
LQATMKSLQSQKQEVIHSLETQKEREGKLKADEEQLQLVFETMQEQHNNKKEEKEQRQQT
EMEKETDRQRDQERLKNLELQHQRDEQKIKELQEI---LAVLELRESPSSSNNQRELLCA
LNKDQNAKQPMTKES-----EKLNLQQQQQQLEKIRQQLLFVAACLNEFIYKIVASKL-M
WVMAESPVLKEMS-SV-----------SLPL--LTRPTLSNNE-ALASLLQM-LK-ELKS
DLLSPPASQYSWYNKLPLVSGSSLN--FSFRSTDDA------------DSVQQL-ERDAW
-QQERSILQNALKRAESELAKATAEIENKPVVETSSPK-SDTPKLQKLYRKYLRAESFRK
ALV-YQKKYLLLLLGGFQDCEQATLSLIARMGIYPAPADLQLSVSHSRPFTKFRCAVRAV
IAVSRL--KFLVKKWNKLNIQEVI-QAVLSGF----------------------------
--------------SVSPPTRDTGLCH-RTSSGRFLSHSPRSSHWSHNRSVCSLHSVQLP
YWAVFPKNNARSTPSTSSASEKSFVPTQDPERSLTEYIHHLEVIQQRLGGLQLG--KRN-
HATSQN------------

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-----------MEAAEQKQRRGKVEAGRAKLAHFRQRKTKGDCANSEKKTSK--------
------RKGSAVDAPVQEES--PVATD-DGACLG-GGG--VCESTACV-------DSPDG
ARGAFA----AQVDQLGVDI----------------------------------------
------------------------------------------------------------
---------------------CFQF-----------------------------------
---------------------------------SLAR-------------------HSYF
VATV--------S--------SC-P--------FWAMSFA------FLPQECE-QECEPE
IAELVGR----PDGQQ----------------------------CFSPLQTVHSLELEAL
RLSLSNMHTVQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----MALRCSQETAELKEKLHSEME-KNVQMIETLKQDWESERDL---------
---------------CLEKLRKELSAKHQLEMEDLRSQFQEEL--------AEQKAELEK
IFQAKNQAEST-LENLEAQYEAAIKKLREDLQSERCRYLEDLELKFKEKEKEKQ----LE
LETLQASYEDLKAQSQEEIRRLWSQLD-----STRTDRQELN-ELHEQFLARASHQQ---
-------------------QQEK--TQHESELEQLRIYFEEKLRDAEKTYQEDLTLLQHR
LQEVREDSLLGSVE-------ISLS----CTRLEETPE--KGKTGRLDQLDLQ-------
----PEQHEESPACFQAELVENHTCELEAWKSPLRTQH---ERDVVDRCLLG------TE
VLGREH---L---ELEGHLREPCLQLALVHPPCAQDAALEVDTEVAARVLD-LETEHRVK
LSLLQTE------LREEIELLKIENRNLH-EKLQHEIRLKEDLEKVKHNLVEVHQEELNK
TKEKNQLMKQELKKKEAEWKVLSEDLKREAEEKLTLMLLELRGKAESEKQSVVNKFQLRE
KEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQGLAAEEAP---LCNRCGREPPL-------GDG--ER
ALRVQEDCTLQLMLARNRFLEE----------------------RKEITEKFNAEQDAVL
QEAQEKHAHEL----E----LLQERHQQQLQAVSRELEARHQAELCELAASLESERRALL
DARVAELQTKHAAEIHALEARHRSSLDSMQSCCLAEIQTVRDEHRRAVAHLQADFVEQLQ
RKDAVHQTILSQELEKLKLRHDKELQSAQDGLPGATTL--AG-----T------LG----
------------------------------------------------------S-----
------------------------------------------------------------
----------------------------CRSWGEFESEKKAALHAKQETCGLEGEQAQAL
CRKEKESWS-LQLQEKDDQIQQLEEQVL-SLSHKVEESRSELETLQQRRERENQEGENLI
SMLKADVDLSQSERRALQDALKRLLALFGETLKAAVALRSQIGERVGLCLDDAG---A--
-T------------GAAPTLDETWS--DAAL------LEVDRTVSECA------------
---EMSSAAEVSSHVRESFLMSPDSALGCEQTVRRVYRSLGLAVDGLLEMVLDSTRQLEE
AQQIHSRFEKEFSCKNEETAQVVRKHKELLACLEEQSAAKAGLELELHTAEGILEGLKVE
KADLQEALGRKEESERQLVLELEGLRQQLTQAA------GEQASLREEYALLWSQKEAAA
GEAEEREA------------ALRKEVECLTREQSETRKQSEKDRVALLSQMKVLECELEE
QLSQHQGCARQAEE-VTALKQQMASLDKHLRNQRHFMDEQAAEREHEREEFQQEIQRLEA
QLRHV--ARPQPQGLLDSPQ-----HARLDEEVELLQQKLREKSDGFNELVIKKELADRQ
VLIQEEEI-------KRLEEMNAHTRRKVVQLQEELEKQKKIVKEL-QDKEALKEQQMTH
LPLESTLQ-AGLGEGRCPGPLPDSP-PAGPEVQWESAQRAPLQRDSEVGGSRGAGPALG-
---VGNE--FRLNCVLK---EGNSGVGVLIGLRNVLSLQ---------------------
------------------------------------VVCTRSSEIEELKATIENLRENQE
RLQKDKAEEIERLHEVIEKLQQELSLMAPAAQGASDSRAGSLQSEL----LCSQA-EG--
---------------------PCGQALQGELQAALAAKEALSQLLADQALGHSQALEALR
QRLQGAEEAAARQLAEL-----------------GRSVALREAEVEGMASRIQEFEAALK
AKEATIAERDSEIDAVNKWKAAHSTALKAVLSA-VARFRCALEQ--------QPLAGP--
AEPPELQRLRTQCVRLSRQLQVLNQRFLKCQMELDRQQVHGAAARTR----------PPG
ACRHPGLEGGTEVWMLRDAEH-------LEGPR-----------AH--------------
----QGISPLCG------STALLCV-SPF-----------------------------YL
----------------------------QGKEKV-LEDYQLQKVDLIAQVKQLQEKLNHL
VYSVTFQDVNTADFKFQQPLAS-AFGLENSSS--DGS-----------------------
-HNGEETDKSPPVGAFNIDKTV---------------------RDLT-------------
--V-------AIKDQDYLIRN-EMPNFPIQETLELQDGSHSLPT----------------
-----------------------------CVRGGARALSCSDLPEPLKSPVRVLDLSSWS
SPEVLRKDS-ALEPQPS---LLLTPHSDVLSLCSADASLQDRTPASLLLA-DEPGLPCYL
GVSA---AGQAPPWAESAP-----------------------ADH-RPVERTPVEKDVED
FIITSFDSQETLRSP---------PVGLEENND-GSEDSDGLGFGGKLSPRSEGPE----
---------APADGPI---------SRRSQQPPGAMKGK-DVQAQHVKALLQMVREESRQ
ILALSESRGPPG----E-------------PCAPLDPIPR-EGQAVSL-H----------
GCRSQEPADVCLDWRGEFLQVVQEAFD--KEWKMLKLQLQPGRGG-SDPGGRDCLLERLE
KVVHAQGD----LQEKSLEHLHMSDRSSLLSEIQALRAQLRLTHLQNQEKLQQLCTALTS
VEARGSWQEHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLSEEQ
EKANGVRKLLAVEQSAVKALKSELCECKQENERLLKSLDNVQQEVLQLR-----------
-----------------SMLDGKENDLQA-------------ALQELECE----------
--RGKERVLQSRLEEQQL---------------------RHLQREGQSSKSLE-ELRASL
EKQRAQS--SRLCVALKHEQTA-RDNLQKELRIEH----------SRFEALLAQEQGR--
-LSQLQKDLEAEK-SHSLEL------SEALQHERLLTEQLSRRTQEAGTH--QDA-----
-QAHPAVLRKLKEEKARVLELQAVLEKA-------QQQLEAEAQ-KRCEELRREKEVSAA
LTPTVEALQTQKRELRCCLEREREKPAWLQADLAQSRTRQKEPEGPEDTRSGAETRQSRA
RAGKWRKWQREKEKLRELELQRQREEHKIRQLQQT---VRELESKEEALRSGGLHRGAPR
----G-------APGSD---GPDQLQEQQQELERIRQQLLCAAGLLTSFVRRTVG---SD
WTSSNEKAVASLLRTLEELKRGPPRPVLHSRRPDKKMAAELQI-QLVDVLLK-ENDSLTK
ALNTATEEKAELSRAVSRLE---KT--LKHHVVRI--------------CTFSS-SDRPA
WKQDPVVPQSS-QHSDLGRPPP---------AASVEAN-TCNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKRI--TASRPFTKFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAP-GKAPR--P-----GPRAPRRQRSP---------
-----------PEPRESLPTRDVSSGHTRDPAR-----------------------GPGP
VTAASLSRRGRSTPSPNSRLERSLTASEDPEHSLTEYIHHLETIQQRLGGLPPD--FTS-
KKSCHPKSKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGPAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQLEDRDGEKREDLEQLQQ----------------KQV---SDHPPEQQ-
------------------------------------------------------------
-------------------Q-CEIITVSDH-HPEQRG------MFTV-SDHPPEQR--GM
FTVSDHPPEQHEIFTVSDPHPEQRGMFTVSDC-HPEQREIFTVSD----------HHPEE
REIF--------T--------VS-D--------HPPEQRG-----IFTTKECK-QECELA
IADLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEKE-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEVRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KGRKDHVDELN---------
----PERHKESLPCFQAELEESHRHLLEAPESPLCVQH---EGHVSDRCCAE------TS
ALGQGW---H---LEPS--EGRSQELPWAHLRGVQDRASEADAEVAARVLG-LETERKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKRNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLDLREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPT-------AQDGELA
ALHMKEDCALQLILARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLR
KQDSLHQTILTQELEKLKQKHDEELRSVRDGLRTAAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKAALHEKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKRNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAITLRSRIGERVGLCLDDAG---A--
-GLAL---------LAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSMAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
MDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVELLQQKLREKLDEFNELALQKESADRQ
VLRQEEEI-------KRLEETNINIRKKMAELQEEVEKQKNIVKELAQDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQSALLQRESEVLDLKEQLEKMKG
DLESKHEEILHLNLKLDL-QNSQTAVRLGELQEESVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEVEQLHEVIEKLQQELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHGQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDVLNQRKVAHSAELEAVLLA-LAHIRRALEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLQVLHQRFLRCQVELDRRQASRTTAHTR----------VPG
AHPQPCVDGGAKAQVPGDMEA-------SHDGALE--P--VVPDPQ-------GDLQPV-
-LMTLEDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFPNVDAADATSPWPLAS-AHLSESSWS--DGS-----------------------
-CDGEEPDASAPTDTCDASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SMRGGSHHQSHAAEAGPQKSPVGMLDLSSWS
SPEVLRKDW-PLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQP-QGPGLLCSP
GVSA---AALALRWAESPP-----------------------ADD-HHVRRTAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGARLSPGSGGPE----
---------APTAGPVT----PAAISGRFQPLPEAMKEK-EVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVQEDLLYGG-K----------
MQ---DVPTVCPDWRGELLQVVQEAFE--KEQEIQGIELQPRLSG-SDLGGHSFPLERLE
KVISEQGD----LQEKSLEQLRLPDRSSLLSEIQALRAQLRMAHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQSVVRDLKSELCESRQENERLSRSLSEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLGVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVS-GSRLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAIDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
IAVLRL--RFLVKKWQEVDRKGALAQ-GKVPR--PDNSGEGPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHGL
AAAASPHIGGRATPSPNSRLERSLTASQDPEHSLTEYIHQLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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-----------MEDDEQEQRRRKVEAGTPSLAHFRQRKTKGDCTHSKKTPAK--------
------RKGTTVNAPVAEES--PVAAPGDGGPLG-GLD--IGKNPTCS-------DTPDG
AEAAQI----RQVFFFNLKVLK----LEERGVHCPLPFYPYGR--------GGKPPKQ--
-------DSLK-------------------------------------------------
----------IIQHHHEGNKLQKMFRVETE-PSR--------------ERTPPKLD--GH
C------AEQPGV-------MTKVSVIDQCASQAWPTL----------------------
------------R--------RC-RGQASRLGVSVTVP-APPRVLGVTSMDIEILDTQFW
LDSVHTTYSSEQG--------------------------------LEKWSLMESLELEVL
RLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEA
EIQANTKRLFHVLPCFCLAAELKEKLQSEME-KNAQMIEILKQDWESERDS---------
---------------CLENLRQELLEKHRSELENLQNQFKKEL--------AQQKAELEK
VFQAKNQAECS-LQTQEAQHEASLSKLRADLQLEHCQYLEELERKFQEKEKENQ----LE
LERLRASYEELQARSREEIQCLGAQLE-----SARSSRQELS-ELREQLLARASHVEELE
LLKRDLEQQ---------QQQER--SRHESELEQLRLYFEEKLREAERSYQEDLTLLQRR
LQEGRDDSLLEAMG-------TSFSLNSPSACLEETPE---EERDHPDRLGLQ-------
----REQLEGFSS--SVEENRALGHPLGVLQLPLCPLHPLPASRVCG----Q------LT
GFG--------GAWPSDDSAPGPTELAREPLLCAQSTALDLETEVPAGDLG-LETAHRAQ
LVLLPVE------LKEEIDLLKVENRNLQ-EKLQREICLKEDLEKMKQNLVEAHQEELKS
AEERIEQMKQELREREAEWKVTSEDLRRGAEERLTKMLLDLREQVESEKRSMMNRFELRE
SEMRQLQDQQAA------------------------------------------------
---QILDLEGSLVEQQGRLRQLELGLPGDESL---RCSQCGRELGCG--PAPGAQDQELA
MLHLKEDCALQLKVAQSRFLEE----------------------RRAVTEKLAAEQDAFL
REAQKQHAHEL----R----LLQEGHQRHILSLTAELETRRQAEVDALRSSFERERWALA
EAREAESQVKHVAEVSVLEARHASHLDALRLQYLSELQAVQGRHRRALELLRLDLEERLQ
KEDVAHHGVLTQVLELLELRCAEEPQSAEDSLRGDGSM--EPPEGVRALWL--HG-----
------------------------------------------------------------
------------------------------------------------------------
-----------------------------ARKGEFGSERKAALHEKEEIPKLEHEKAHSL
YEKEKESLS-LQLQEKNNQILQLKDQIL-SLNREIEERHSELEKLQQRRERENQEGTALI
AMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDHSPCMY--
----S---------LAAPALDDVWAGLDVAS------LEPDGTVAECA------------
---ETSSVAEISSHVCESFFLSPERTLDCEQPVRRIFQSLGLAVDGLLDMVLDSAKQLEE
ARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLVLELHKAEGIIEGFKEE
KAGLQEALGQKEASERDLVGELEGLRQQLQRAA------RRQAELREENAELCSQTEALA
VDARERE------------AALRREVESLTQEQSEARRQADKDRAALLSQMRLLEAELEE
QLSHQQACAQQAEE-LAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEE
QLRQA--ARPRSPGLRDSH------PAEVPPEVELLEEKLREKSDGLNELILKKELVDRQ
VLIQGEEI-------RRLEETNASTTRKLLQLQEELETQRRAVQALQQDKEALQEQQMCN
LLQVSALQ-SRLDEGKCPVPPEGSC-HDRAEAQLEAVQGALRQREAEVLDLKDQLENLKD
DLVNKNEEILHLNWKLGL-QDNSTAASIKELQEENARL----------------------
-----------------------------------KVVCSRSSEVEELKSIIETLRENQA
RLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMRLQ----SELLGLPAEGAEA
P----------------AMLA-ARAMLAGELHAALGPRRALTQRLAEQERQHSQALEGLQ
QRLQAAEEAATRQLAEL-----------------G---------PEGLASQILEFEAALR
AREAKIAERDLEIEALRREKSTHSAELEAILAA-VARFRHALEQ--------QLLVAT--
GEPPELQRLRKQCVCLSRQLQALNQRFLKCQKELDERQAHGE-----------------G
GSQGWVPRGEETSCSEESQQAV-DGRQLAQ----A--LDGRGSDPQ-------DDLQPSK
ALPALTCTRPSQ------QDSVISV-LTVCQQQLESEL--LLVKK-----EMCLRAEDGG
R---------------------------EDKGKL-LEDCRLQKVDLIAQVKQLQEKLNHL
VCSMSFQNIEMEDFKYQQAVAS-PCALEDGLS--DGS-----------------------
-DNSEETDKSPPIDTFNIL------------------------WDLA-------------
--E-------VTGNSDSLIRN-E-PDAPAGEPVTLRDRSLCLQG----------------
-----------------------------HLRGRSRGLTRSQGSKPLKSVLRTMDLSPWS
SPEVVREDS-AFEPPPS---LPLTPCSDALSLHSLDTSLWDGTSTHLLQA-AQSGQLCYP
GESA---AGTAPKWVGSPL-----------------AADSAPSAD-HHAQRVPVEKDVED
FIITSLDSQEKSRSP---------PLGLEGKSD-GK--SDGVEFAEPLSQDSGRLG----
---------APAASPAA----PLITPRDCRRPLDAMKEK-EVHPKQVKALLQMVCDESHH
ILALSEYRGPPHILSRSE------------PSAPLEEHPTPGSQKGEKVQA---------
---FKASSNVGLDWSGDFLQAVQGAFE--KEREMLRVELSF--------GSHVSLAQFVL
LTMKSQGD----QQERSLERLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTS
AEARGSRQEHRLRRQVELLAYKV-------------------EQEKCIASDLQKTLNEEQ
EKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQMR-----------
-----------------SMLDSKESDLQA-------------ALQQLEGE----------
--RMKEQALQSQLEEERL---------------------QHLPREGPSAKSLEEELRASL
EQQCAQS--NQLCVVLKHEQTA-KDNLRQELQIEA----------SRCEALLAQERGH--
-MSELQRSLEAER-DRAREL------SEALQHERVLTERLSRRPQER-------------
-PPHQALLQKLRAREGGGRGGAR-----RRHAL------EAEAR-VHREEVEREQEVSAA
PKTPPETLPG-----------TRERPAWGQGQVEQD--------ACKDARMGAELRPSRA
DTQLWSRWQRDKETLRELELQRQRDEHKIQQLQRT---VQELQARVAL---P--------
---------------SA---EPERLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISD
WTSSNEKAVASLLHTLETLKSELGTSSSC----RKKTAAELQI-QLVDVLLK-DNESLSR
ALSTVTREKAELCKALSRLE---RTHRAPRTLQEG--------------CTRKR-SDRSA
WKQDKTVSPGSARHPDPALDAG---------ACSAKVSASPRAVMEKLYLRYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKA--TESRPFTRFRTAVRVV
IAVLRL--RFLVKKWQQVDGRGALAP-GQVLR--PGE-G--FLVPRRQQSP---------
-----------PVTRESPPTRDVSSSQPRDPVS---------------------KASPR-
-------RRERSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGMPPE--STS-
KKSCCQKIKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDGSHSEKKTAK--------
------RKGSAVDAPVQEES--PIAKE-DRALRG-GGD--ICKSTSCD-------DTPDG
AALDLA----LNA-------------SFW----------------PSP---YDHPPEQQ-
------------------------------------------------------------
-------------------Q-RGMFTVSDH-HPEQRG------IFTVISDHHPEQR--GM
FTVSDHHPEQRGMFTVSDHRPEQPGIFTVSDH-RPEQRGMFTVSD----------HHPEQ
RGMF--------T--------VS-D--------PHPEQRE------VITKECK-QECELA
IADLQSSREEEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTVQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAESA-LRNLESQHQAAIEKLREDLQSEHCRCLEDLEFKFKEGEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDPVE-------VGLS----CVGLEEKPE--KGRKDHVDELD---------
----PERHKESLPCFQAELEESHRHLLEAPESPLCIQH---EGHVSDRCCAE------TS
ALGPGW---H---LEPS--EGRSQELPWVHLQGVQDRALEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKENLEKVKHNLVEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIVNKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQELTSDDAL---RCSQCGREPPA-------AQDGELA
ALHMKEDCALQLILARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHTREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEIQTIREEHRRALELLRADFEEQLQ
KQDSLHQTILTQELEKLKQKHDEELQSVRDGLRTAAST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GAHQGEFGSEKKAALHEKEKTLWLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEALQQRRERENREGANLL
SMLKADVDLSHSERGALQDALRRLLGLFGETLRAAIALRSRIGERVGLCLDDAG---A--
-GLAL---------SAAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSAAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKETLAGKEDSEHRLVLELESLRRQLQQAA------QEQAVLREECTRLWSRGEATA
MDAEAREA------------ALRKEVEDLTREQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQV--AKPQPWGPHDSQ------QAPLDGEVSRRHRDGHAL-----------------
---------------------------------------CGRPGSPALDKELLKKQQMSS
LLLASTLQ-STLDAGSCPEPPPGSP-PEGPEVQLEVTQS--------VLDLKEQLEKMKG
DLESKNEEILHLNLKLDL-QNSQTAVRLGELQEESVSSK---------------------
------------------------------------VVYTRSSEIEELKATIENLRENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERGHSQALEALQ
QRLQGAEEAAERQLAEL-----------------ERSAALREAEVEGMASRIQEFEAALK
AKEAMIAERNLEIDTLNQRKVAHSAELEAVLLA-LAHIRRVLEQ--------QPLAAG--
AEPPELQRLRAQCARLSRQLHVLHQRFLRCQVELDRRQTCRTTAHTR----------VPG
AHPQPHVDGGAKAQVPGDIEA-------SHDGALE--P--VVPDPQ-------GDLQTV-
-VMTLEDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDVG
----------------------------KGKEKV-LEDCQLQKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLENSWS--DGS-----------------------
-CDGEEPDTSAPTDACVASAAT---------------------GGVT-------------
--D-------VIKNRDSLIPD-EMPDSPIQEKSECQDRSLSSPT----------------
-----------------------------SMLGGSCRQSHAAEAGPRKSPVGVLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLRDRADTSLPQP-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HRVQRTAVEKDVED
FITTSLDSQETLSSP---------PPGLEGKTD-GSEKSDGSGFGARLSPGSGGPE----
---------APTAGPVT----PAAISGRFQPLPEAMKEK-GVHPQHVKALLQMVCDESHQ
ILALSEGLAPLT----GE------------PHPPRKGDKVREDLLCGG-K----------
TQFCFDVPTVCPDWRGELLQVVQEAFE--KEPEIQGVELQPRLSG-SDLGGHSFPLERLE
KAISEQGD----LQEKSLEQLRLPDRSSLLSEIQALRAQLRMAHLQNQEKLQHLRTALTS
AEARGSQQEHQLRKQVELLVYKV-------------------EQEKCIAGDLQKTLSEEQ
EKAHGVQKLLAAEQSVVRDLKSELCESRQESERLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQREGQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQQELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLRKLKDEKSRVADLQAMLEKVQQQALRSQQQLEAEAQ-EHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEAGQSPA
AAERWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGLD----ADHLREQQRELEAMRQRLLCAAGLLTSFASQAMDRTVND
WTSSNEKAVVSLLHTLEELKSDLSRPTSS----QKKMAAELQL-QFVDVLLK-DNVSLTK
ALSTVTREKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSK-SERAA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-PSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---TTSRPFTRFRTAVRVV
VAVLRL--RFLVKKWQEVDRKGALAQ-GKVLR--P-----GPRVRR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPTR-----------------------GHGL
AAAASPHTGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGALPD--SPS-
KKSCHQKIKQ--------

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------------------------------LASFRQRKTKGDCPNSKKKTAK--------
------RKGSAVNAPVQEEG--SVAPQ-NSELPQ-GGA--GFESTSCS-------NTLEG
TRGAFA----AQERQD-----------------CELDEP---------------------
------------------------------------------------------------
-----------------------------------------------------GL-----
------------------------------------------------------------
------------------------QAQQQ---QPQPQP-QPTQ-----------------
--------------------------------------------------TAHSLELEAL
RLSLNNMHTAQLELTQANLQKEKETALTELREMLNGRRAQELALLQSRQQCELELMREQL
AREKEE----VVLRCGQETAELKEKLRSEME-KSVQMIETLKQDWESERQL---------
---------------CLENLRKELSAKHQSEMEGLQNQFQREL--------AEQRAELEK
IFQAKHEAEVS-LK--ETQHQAAVKKLQEDLQSEHCQYLQDLEMKFREKEKEKE----LE
LENLQASYEELKAQSQEEIRCLWSQLE-----SVKTNTEELN-GSWEPCLAQDSHLEELE
HLRSDFAQQQ--------QQERR--AQHELELEHLRVYFEKKLRDAEKTYQEDLTLFQQR
LQEARED-SLESGE-------ISSS----CIFPEETSG--RGRKEQPDPLDL--------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------QLEQLKVKHSLVEDHQVKLNK
AEEKIQLMKQEFQKKEAEWERSHEDFKRDTEGRLTSMFIELREKAESEKQSIISRFEHRE
SGMRHLQEQQAA------------------------------------------------
---QILDLERSLMEQQGRLRQLEQELTRDEVL---PCSRCGQEPLM------AQDEEHIM
LLRVKEDCALQLMMAQNRFLEE----------------------RKEIMEKFAKEQDAFL
RDTQEKHAHEL----Q----LLQQGHQQQLQALKIELETKHHSELAEQLASLESKQQALV
ETHVAELQVKHNAEISTLQMKHLTDLHAAKSFYLTDIETIRDEHRKALELLQAELEDQLQ
KKDSSHKEILTHELEKLK---HEELQSAKDSLRIKIHA--KHTEEAKGLAT---DMQGTQ
QEELAMAVHN---QRHLLGKDGNAALGS---------------VGAEVLL----H-----
------------------------------------------------------------
----------------------------PAVPQELG-----------DPHAVEMQKPQ--
----AELAKSQELPASQEQAALVRIPVF-SLSREVEECRAELERLQQRRERENQEDTTLI
CMLRADADLAQSKGKVLRDALRRLLGLFGETLKAAVTLKSRISERAGLLLDHVDATDT--
-SDAQ---------LAAAALGDMWSD--EGL------LEIDRTLPEGA------------
---ETSSVSEISSHVCESFFMSPENTLECEQPIRKVYQSLSTAVDGLLEMALDSSKQLEE
AHQLHCCVEKELRHRNEEMAQAVQKQQELLEHLRQESAAKDGLTLELHMAEGLLEGLRVE
KAELQEALDKKEESEQQLILELESLQKQLQQVA------QELVTLREENSVLWNQKETFT
NEAKERE------------AALQKEVESLSRDQWEARKQSEKDRATLLSQMRVLESELED
QLVQHRGCAQLTEE-VATLKQELAALDKHLRSQRQFMDEQAAEREHEREEFQQEIQRLEE
QLRQA--ARPRPPGPRDSQ------VG---QPVELLQEKLREKLDGFNELVIKKDFADQQ
LLIQEKEI-------KRLEETNVSLQRQVAQLQEELEKQKKNMEEL-KVK--FWQELTSD
LLLPPVSQ-CRLDEAECPKPSQDSS-SRGPETQPEVTESTHLEPES--------------
------------------------------------------------------------
-----------------------------------EVVPSRNSEIEELKAIIENLRENQE
QLQKDKAEEIEQLHEVIEKLQSELTLMGPKVHELSDHQASSLH----TELSCLRAEGQH-
-----------------------GQALWNELEAAQAAKEVFGQLLADQAHGHSQVLEALQ
QRLQDAEVVAAKRLAEL-----------------EHCVALREAEVEGMASRIQEFEALLK
AKEAIIVQRDLEIDSMNKWKATHSLELETILLP-LAHFRRALEQ--------QTLATS--
DEPPELQQLRIQCARLSHQLQVLHHRFLQCQMEPDQQQAPVAPADC--------------
----SSP------GA------D--------------------------------------
--------AQWQ------QDSVSMG-LAS---------------------------FARS
L---SS----------------------QAKEQQ-LEDCQLGSGDLIIQVQQLQEKLNHL
VHSMASRDTSMENPKSER-----PSLSENGSS--SDC-----------------------
-HNDEDISASLPIDVFSIGKTT---------------------WDVI-------------
--D-------VIKNQDLLAQV-EMPSFPTQEPLTPQGGSLSSQV----------------
-----------------------------SVHSDS--LHPEE-AEPQKDPARALDLSSWS
SPEVLRKDS-TPEPQHS---LPLTPCTGTVSLHSVDTSSQDWTDS-LQLA-DASGLLCYP
GKSA---TAQAPLWVVT------------------------PSAENHHVERPATEKDVED
FIVTSFDSQELLTTS----------PHELTRSD-ATGKSDCPSGGMMLTLGSGGSE----
---------TPRSSPVAA--AVVPFSRRFDQSPGAMKEK-EIHAKHMKALLQMVFDESHQ
ILALSKNQDLPNSLSKGE------------PRDPLDGLPRDRQALLEATA----------
DRGEKEPSETCLTWSGELLRAIQEVFA--REQE--NAELQSRPYG-LDLGDYNVLFKRLE
KVIKEQGD----LQ-KV---QCLPDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCAALTS
TEARGSQREHQLRRQVELLAYKV-------------------EQEKCIASDLQKTLNKEQ
EKASDVRKLLMVEQSAVQDLKSELHACKQENTRLLESLDKVQQEVLRLRYGPSPY-----
-----TALMAARCFPPRAMLDGKENELKG-------------VLQELECE----------
--RGKERALQAQHEEQQL---------------------RHLQREGQSSRALE-ELKMSL
EKQRAQN--NQLCVALKHERAA-KDNLQKELQIES----------SRCEALLAQEKGQ--
-LSELQKSLEAER-SRSLEL------SEALQHERLLTEQLSRNMQEACAR--QET-----
-QIQHALLRKLKAEKARALELESMLEKVKKEAA---------------------------
---------------------------------------------HTQQQLESQAQ----
----ERCVELRKEKERELELQCQRDEHKIEQLQQM---VRELKRKEKVPGGDGACRVSPR
----LG---------SL---DLDHVQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKD
WTSSNEKAVSSLMRTLEELKSELSIPASS----KKKMAAELHV-QLMNELLR-DNDTLTK
AISMATQEKAELCRTVSRLE---KT--LKHHMQKG--------------CILSR-QSKSS
GKQDGMVPQSPLRNSDPEWHTA---------TTSMEAN-TYNTKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKI--TTSRPFTKFRTAVRVV
IAIQSW--QWL------------------------RH-----RMSRRQHSL---------
-----------SETRASLPSKEVSSGHTKDARH-----------------------SLRS
LAAVPLGKVERSTSSPNSRLERSLTASQDPEHSLTEYIHHLEMIQQRLGGLPAD--S-T-
QKSCHQKVKQ--------

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-------------------SAQKVE--AGRLAHFRQRKTKGDSSHSEKKTAK--------
------RKGSAVNAPVQEES--SVAKE-DSALRG-GGD--ICKSTSCD-------NTPDG
AGGAFA----AQLEDRDGEKREDLEQLQQ----------------KQV---NDHPPEQH-
-GMFTISD----------------------------------------------------
---------------HSPEQ-RGMFTMSDH-PPEQRG------MFTM-SDDRPEQR--GM
FTISDHPPEQRGMFTMSDD--------------RSEQRGMFTVEQ-----------HPEQ
RGMF--------T--------IS-D--------HHPEQCG-----MF-T-ECE-QECELA
ITDLESGREDEAGLQQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELT------------------------QELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAEWA-LRNLESHHQAAIEKLREELQSEHGRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARASHVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGASEDALLDSVE-------VGLS----CVGLEEKPE--KGRKDHVDELE---------
----PERHKESLPCFQAELEESHRHQLEALESPLCIQH---EGHVPDRCCAE------TS
ALEHGW---R---LEPS--KGHSQELPWVRLQGVQDGDLEADTEVAARVLG-LETEHKVK
LSLLQTE------LKEEIELLKIENRNLY-EKLQHETRLKEDLEKVKHNLIEDHQEELNN
AKQKTELMKQEFQKKEMDWKVMKEELQQEAEEKLTLMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQDLTSDDAL---HCSQCGREPPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHAREL----Q----LLQERHQQRLLSVTAELEARHQAALGELTASLESKHGALL
AARVAELQTKHAADLSALETRHLSSLDSLESCYLSEFQTIREEHRRALELLRADFEEQLR
KKDSLHQTILTQELEKLKRKHDGELQSVRDHLQTEAST--EL---AGTVA---HKL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GTHQGEFGSEKKTALHEKEETLQLQSAQAQPF
HQEEKESLS-LQLQKRNHQVQQLKDQVL-SLSHEIEECRSELEVLQQRRERENREGTNLV
SMLKADVDLSHSERGALQDALRA-----------------GSGSAWGFCLDNAG---A--
-GLAL---------SASPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLLEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESTAKAELALELHKTQGTLEGFKVE
TADLKEALAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEAAA
TDAKAREA------------ALWKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEV-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--AKPQPWGPRDSQ------QAPLDGEVELLQQKLREKLDEFNELAIQKESADRQ
VLMQEEEI-------KRLEEMNINIRKKVAQLREEVEKQKNVVKELEQDKEVLKKRQVSS
LLLASTLQ-STPDADRCPEPPSGSP-PEGPEVQLEVTQSPLLQRESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLDM-QNSQTAISLRELQEENTSLK---------------------
------------------------------------VIYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PHGQALQGELEAALEAKEALSRLLADQEHGHSQALEALQ
QRLQSAEEAAERQLAEL-----------------ERSAALREAEVEGVASRIQEFEASLK
AKEAMIAERNLEIDALNQQKAAHSAELEAVLLA-LARIRRALEQ--------QPLAAG--
AEPPELQRLCAQCARLSRQLQVLHQQFPRCQVELDRRQARRATAHTR----------VPG
AHPQPHMDGGAKAQVTGDVEA-------SHDAALE--P--VVPDPQ-------GDLQPV-
-LVTLKDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRVSLEDGG
----------------------------KGREKV-LEDCQLPKVDLIAQVKQLQEKLNRL
LYSMTFQNVDAADAKSPWPLAS-AHLLESSWS--DDS-----------------------
-CDGEEPDTSPPVDTCDANTATGGVTDVIRNQAIDACDANTTTGGVT-------------
--D-------VIKNWDSLITD-EMLESPIQEKSECQDRSLSSPT----------------
-----------------------------SVLGGSRHQSHTAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPRPS---LPVTPHSGALSLCSADTSLGDRADTSLPQT-QGPGLLCSL
GMSA---AALALQWAESPP-----------------------ADD-HHVQRTAVEKDVED
FITTSFDSQETLSSP---------PPGLEGKTD-RSEKSDGLGFGARLSPRSGGPE----
---------AGTAGPVT----PAPISGRFQPLQEAMKEK-EVHPKHVKALLQMVRDESHQ
ILALSEGLAPPS----CE------------PHSPRKEDEVQDSSF---------------
-----EVPTACPDWRGDLLQVVQEAFE--KEQEMQGVGLQPRLSG-SDLGGHRSLLERLE
KIIHEQGD----LQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQHLHTALTS
AESRGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANGVQKLLAAEQIVVRDLKSDLCESRQKNEQLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRSLQSQLEEEQL---------------------RHLQREGQSAKALE-ELQASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLVQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHRALLRKLKEEKTRVVDLQAMLEKVQQQALRSQQQLEAEAQ-KHCEALRREKEVSAT
LKSTVEALHTQKREPRCSLEREREKPVWLQAELEQSHPRLKEQEGRKAARRSAEARQSPA
AAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEAMRQRLLSAARLLTSFASQAVDRTVND
WTSSSEKAAMSLLHTLEELKSDLSRPTSS----QKKMAAELQF-QFVDILLK-DNVSLTK
ALSTVTQEKLELSRAVSKLE---KM--LKHHLQKG--------------CSPSR-SERSA
WKPDETASQSSLRRPDPSRLPP---------AANEEAH-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFTRFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAPR--P-----GPRARR-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GHRL
AAAASPHSGGRATPSPNSRLERSLTASQDQEHSLTEYIHHLEVIQQRLGGVLPD--STS-
KKSCHQTIKQ--------

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-----------MEDDEQEQRRRKVEAGRAKLAHFRQRKTKGDCTHSKKTPAK--------
------RKGTTVNAPVTEES--PVAAPGNTGPLG-GLD--IGKNPTCS-------DTPDG
AEAAQS----RAARGH-----------------DE-------------------------
------------------------------------------------------------
------------------------------------------------------------
--------GELS------------------------------------------------
------------------------LGSLLRLGVSVTVP-APPR-----------------
--------------------------------------------------VVSELELEVL
RLSLSDMHAARLERTQAHLQREKEAALAELHAELTGRHAQERALLQSRARRELELVREEA
GRQPG----GVDRRSWLESSELKEKLQSEIE-KNAQMMEILKQDWESERDS---------
---------------CLENLRQELLEKHRSELENLQNQFKKEL--------AQQKAEFEK
VFQAKNQAECS-LQTQEAQHEASLSKLRADLQLEHCQYLEELERKFRKKEKENQ----LE
LERLRASYEELQAQSREEIQCLGAQLE-----SARSSRQELS-ELREQLLARASHVEELE
LLKRDLEQQ---------QQQER--SRHESELEQLRLYFEEKLREAEQSYQEDLTLLQRR
LQEGRDDSLLEAMG-------TSSV----CWVPPL-------GR---DGLP---------
------------------------------------------------------------
-------------------P----------------------------------------
---------------------------------KPPLLLHVGPRKVKQNLVEAHQEELKS
AEERIEQIKQELREREAEWKVTSEDLRRGAEEKLTKMLLDLREQVESEKRSMMNRFELRE
SEMRQLQDQQAA------------------------------------------------
---QILDLEGSLVEQQGRLRQLELGLTGDESL---RCSHCGRELGCS--PAPGAQDLELA
ILHLKEDCALQLKVAQSRFLEE----------------------RRAITEKLAAEQDAFL
REAQEQHAHEL----R----LLQEGHQRHILSLTAELETRHQAEVDALRSSLERERLALA
EAREAELQVKHAADINVLEARHASHLDALRLQYLSELQAVQGRHRQALELLRLDLEERLQ
KEDMAHHAVLTQVLELLELRCAEEPQPAEDSLRGDGSV--EPQEGVRAVRL--SMAHK--
------------AEDPSLQERNSAHN-S----GPGGPLVLWKAVCPGLHFQ---------
------------------------------------------------------------
-----------------------------GDPKD-------------------WSDAARV
LEKEKESLS-LQLQEKNNQILQLKDQIL-SLNREVEERHSELEKLQERRERENQEGTALI
AMLKSDVDLSHGERRALQDTLRRLLGLFGETLQTAIALKSRIGERVGLCLEDRSPPTTQP
GGQSP---------PTDPALDDMWAGLDVAS------LEPDGTVAECA------------
---ETSSVAEISSHVCESFFLSPERTLDCEQPVRRVFQSLGLAVDGLLEMVLDSARQLEE
ARQIHSRFEKEFSCKNEETAQVVRKHQELLEQLEAESKAKAQLALELHKAEGIIEGFKEE
KAGLQEALGQKEASERGLVGELEGLRQQLQRAA------RRQAELREENAALCSQTEALA
ADARERE------------AALRREVESLTQEQSEARRQADKDRASLLSQMRFLEAELEE
QLSHQQACARQAEE-LAALRQQIDSLDQHLRRQRQFMDEQAVEREREREDFQQEIQRLEE
QLRQA--ARPRSPGLRDSH------VKTIVSEVELLEEKLREKSDGLNELILKKELVDRQ
VLIQGEEI-------RRLEETNASTTRKLLQLQEELETQRRAVRALQQDKEALQEQQMSN
LLQVSALQ-SRLDEGKCPVPPEGGR-PDRAEAQLEAMQGALRQREA--------------
------------------------------------------------------------
-----------------------------------EVVCNRSSEVEELKSIIETLRENQA
RLQKDNAEEIEQLHEVIEKLQRELPLGGPEAPKAGEGGAMSLQ----SELLGLPAEGAEA
P----------------AV-------LAGELHAALEAKEALSQRLAEQERQHSQALEALQ
QRLQAAEEAATRQLAEL-----------------Q---------PEGLASQIREFEAALH
AREAKIAERDLEIQALRREKSTHSAELEAILAA-VARFRHALEQ--------QLLAAS--
GEPPELQRLREQCVCLSRQLQALNQRFLKCQKELDERQACGE-----------------G
GSQGWVPRGKETSCSEELQQDV-DG-----------------------------------
--------------------------------------------R-----QLAQALDSRG
SDP-------------------------QDKGKL-LEDCRLQKVDLIAQVKQLQEKLNHL
VCSMSFQNIEMEDFKYQQALAS-PCALEDGLS--DGS-----------------------
-DNSEETDKSPPIDTFNII------------------------WDLA-------------
--E-------VTGNSDSLIRN-E-PDAPTGEQVTLQDRSLCLQS----------------
-----------------------------HLHGCSQDLTHSQGSKPLKNVLRTMGLSPWS
SPEVVREDS-TLEPLPN---LPLTPCSDALSLHSLDTSLWDGTSTHVLQA-DQSGRLCYP
GESA---AGTAPKWVGSPL-----------------AADGVPSAN-HHAQRVPVEKDVED
FIITSLDSQEKSRSP---------PLGLEGKSD-GKKKSGGVEFAEPLSQGSGRLG----
---------APTASPAA----PPVTPRDCRRPLDTMKEK-EVHPKQVKALLQMVCDESHH
ILALSEYREPPHILSRSE------------PSARLECLPLGGQGLLEAVPAPREHPTPGS
QKGEKASSNVGLDWKGDFLQTVQEAFE--KEREMLRVELWPQLCG-LGPGGCGSLLERLE
KVVHEQGD----QQERSLEHLCLSDRSSLLSEIQALRAQLRMTHLQNQEKLQQLCTALTS
AEARGSRQEHRLRRQVELLAYKV-------------------EQEKCIASDLQKTLNEEQ
EKANNVRKLLVAEQNAVRDLKSELCECRQDNERLLKSLNDVQKEVLQLR-----------
-----------------SMLDSKESDLQA-------------ALQHLEGE----------
--RMKEQALQSQLEEERL---------------------QHMQREGQSAKTLE-ELRASL
EQQCAQS--NQLCVVLKHEQTA-KDNLRQELQIEA----------SRCEALLAQERGH--
-MSELQRSLEAER-DRAREL------SEALQHERILTERLSRRPQER-------------
-PAHQALLQKLRAQEEHVRELE--------------------VA-L--EAAQR-------
------------------------R------ALEA------------------EAH----
----VHREEVEREQERELELQRQRDEHKIQQLQRT---VQELQARVAL---P--------
---------------NT---EPEHLREQQRGLEKVRQQLLCAAGLLTSFINQTVDRTISD
WTSSNEKAVASLLHTLETLKSELGTSSSC----RKKTAAELQI-QLVDVLLK-DNESLSR
ALSTVTREKAELCKALSRLE---RAHRVPRTLQEG--------------CARKR-SDRSA
WKQDKMVSPGSARHPDPALD----------------AG-ACSAKMEKLYLRYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKA--AGPRPLTRFRTAVRVV
IAVLRL--RFLVKKWQQVDGRGALAP-GQALH--PGE-G--FLVPRRQQSP---------
-----------PVTRESPPTRDVSSSQARDPVP---------------------KASPR-
-------RREKSSPPSNPRSERSLTASQDPEHSLTEYIHHLEMIQQRLGGVLPD--STS-
KKSCCQKMKQ--------

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------------MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAK--------
------RKGSAVDASVQEES--PVTKE-DSALCG-GGD--ICKSTSCD-------DTPDG
AGGAFA----AQPEDCDGEKREDLEQLQQ----------------KQV---NDHPPEQC-
-GMFTVSD----------------------------------------------------
---------------HPPEQ-HGMFTVGDH-PPEQRG------MFTV-SDHPPEQH--GM
FTVSDHPPEQRGMFTISDH--------------QPEQRGMFTVSD----------HTPEQ
RGIF--------T--------IS-D--------HPAEQRG-----MF-TKECE-QECELA
ITDLESGREDEAGLHQ--------------------------------SQAVHGLELEAL
RLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH
AREKEE----VVLRCGQEAAELKEKLQSEME-KNAQIVKTLKEDWESEKDL---------
---------------CLENLRKELSAKHQSEMEDLQNQFQKEL--------AEQRAELEK
IFQDKNQAERA-LRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQ----LE
LENLQASYEDLKAQSQEEIRRLWSQLD-----SARTSRQELS-ELHEQLLARTSRVEDLE
QLK----------------QREK--TQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQR
LQGAREDALLDSVE-------VGLS----CVGLEEKPE--KGRKDHVDELE---------
----PERHKESLPRFQAELEESHRHQLEALESPLCIQH---EGHVSDRCCVE------TS
ALGHEW---R---LEPS--EGHSQELPWVHLQGVQDGDLEADTERAARVLG-LETEHKVQ
LSLLQTE------LKEEIELLKIENRNLY-GKLQHETRLKDDLEKVKHNLIEDHQKELNN
AKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIINKFELRE
AEMRQLQDQQAA------------------------------------------------
---QILDLERSLTEQQGRLQQLEQDLTSDDAL---HCSQCGREPPT-------AQDGELA
ALHVKEDCALQLMLARSRFLEE----------------------RKEITEKFSAEQDAFL
QEAQEQHAREL----Q----LLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALL
AARVAELQTKHAADLGALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLW
KKDSLHQTILTQELEKLKRKHEGELQSVRDHLRTEVST--EL---AGTVA---HEL----
------------------------------------------------------Q-----
------------------------------------------------------------
----------------------------GVHQGEFGSEKKTALHEKEETLRLQSAQAQPF
HQEEKESLS-LQLQKKNHQVQQLKDQVL-SLSHEIEECRSELEVLQQRRERENREGANLL
SMLKADVNLSHSERGALQDALRRLLGLFGETLRAAVTLRSRIGERVGLCLDDAG---A--
-GLAL---------STAPALEETWS--DVAL------PELDRTLSECA------------
---EMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLMEMALDSSRQLEE
ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAELALELHKTQGTLEGFKVE
TADLKEVLAGKEDSEHRLVLELESLRRQLQQAA------QEQAALREECTRLWSRGEATA
TDAEAREA------------ALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELEE
QLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEG
QLRQA--AKPQPWGPRDSQ------QAPLDGEVELLQQKLREKLDEFNELAIQKESADRQ
VLMQEEEI-------KRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQMSS
LLLASTLQ-STLDAGRCPEPPSGSP-PEGPEIQLEVTQRALLRRESEVLDLKEQLEKMKG
DLESKNEEILHLNLKLDM-QNSQTAVSLRELEEENTSLK---------------------
------------------------------------VIYTRSSEIEELKATIENLQENQK
RLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSEL----LCSQA-GG--
---------------------PRGQALQGELEAALEAKEALSRLLADQERRHSQALEALQ
QRLQGAEEAAELQLAEL-----------------ERNVALREAEVEDMASRIQEFEAALK
AKEATIAERNLEIDALNQRKAAHSAELEAVLLA-LARIRRALEQ--------QPLAAG--
AAPPELQWLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATAHTR----------VPG
AHPQPRMDGGAKAQVTGDVEA-------SHDAALE--P--VVPDPQ-------GDLQPV-
-LVTLKDAPLCK------QEGVMSV-LTVCQRQLQSEL--LLVKN-----EMRLSLEDGG
----------------------------KGKEKV-LEDCQLPKVDLVAQVKQLQEKLNRL
LYSMTFQNVDAADTKSLWPMAS-AHLLESSWS--DDS-----------------------
-CDGEEPDISPHIDTCDANTATGGVTDVIKNQAIDACDANTTPGGVT-------------
--D-------VIKNWDSLIPD-EMPDSPIQEKSECQDMSLSSPT----------------
-----------------------------SVLGGSRHQSHTAEAGPRKSPVGMLDLSSWS
SPEVLRKDW-TLEPWPS---LPVTPHSGALSLCSADTSLGDRADTSLPQT-QGPGLLCSP
GVSA---AALALQWAESPP-----------------------ADD-HHVQRTAVEKDVED
FITTSFDSQETLSSP---------PPGLEGKAD-RSEKSDGSGFGARLSPGSGGPE----
---------AQTAGPVT----PASISGRFQPLPEAMKEK-EVRPKHVKALLQMVRDESHQ
ILALSEGLAPPS----GE------------PHPPRKEDEIQDISLHGG-K----------
TQ---EVPTACPDWRGDLLQVVQEAFE--KEQEMQGVELQPRLSG-SDLGGHSSLLERLE
KIIREQGD----LQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQHLRTALTS
AEARGSQQEHQLRRQVELLAYKV-------------------EQEKCIAGDLQKTLSEEQ
EKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLR-----------
-----------------SMLSSKENELKA-------------ALQELESE----------
--QGKGRALQSQLEEEQL---------------------RHLQRESQSAKALE-ELRASL
ETQRAQS--SRLCVALKHEQTA-KDNLQKELRIEH----------SRCEALLAQERSQ--
-LSELQKDLAAEK-SRTLEL------SEALRHERLLTEQLSQRTQEACVH--QDT-----
-QAHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQ-KHCEALRREKEVSAT
LKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPA
AAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQT---VRDLESKDEVP-GSRLHLGSAR
----R-------AAGSD----ADHLREQQRELEAMRQRLLSAARLLTSFTSQAVDRTVND
WTSSNEKAVMSLLHTLEELKSDLSRPTSS----QKKMAAELQF-QFVDVLLK-DNVSLTK
ALSTVTQEKLELSRAVSKLE---KL--LKHHLQKG--------------CSPSR-SERSA
WKPDETAPQSSLRRPDPGRLPP---------AASEEAH-TSNVKMEKLYLHYLRAESFRK
ALI-YQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKAERK---ITSRPFTRFRTAVRVV
IAILRL--RFLVKKWQEVDRKGALAQ-GKAPR--P-----GPRARQ-PQSP---------
-----------PRTRESPPTRDVPSGHTRDPAR-----------------------GRRL
AAAASPHSGGRATPSPNSRLERSLTASQDPEHSLTEYIHHLEVIQQRLGGVLPD--STS-
KKSCHPMIKQ--------

------------------------------------------------------------
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------MHTAHLELTQLNLQKEKETALVELRDALNDKHAQDMALLQKRQHVELENIKEQH
LKERED----TFSKHRQEIADLRTRLEVEKE-NHVQIVEALRRDWQLETDL---------
---------------RLKNLREELTEGHQAEIENVQKVLKAEF--------AEQRAELEK
FSRCKDQA----------------------------------------------------
------------------------------------------EQWREQLLLRTSHVEEIK
HLKQDFELQ---------LQQVN--EEHETELEQLRLYFEQKLRDAEGSYSEDLNLLHQR
LQEMKEDSLMECAE-------VSSS----VEFLEETAE--KERKDLHEQLMLQ-------
----LEQNKEGFISLQLQLEEKHKQELESLRSSLALQK---EDLLEMKRALSDRYTLEIE
ALKKKH-CLELERLRAKLSEEHIKEITKIHLQCVQDTAGHVKEEGAENVL---ENDHRAK
LLLLQSEKQHTSELKEEIEHF--KRELQD-IIVQHERHLKEELEKVKGDSVEDNQNKRKE
GQED--------TPQEEEECKEKEDLRSQTEEKLSLMLFKLERKAEFEKQAIRKQFELRE
AEMKQLQDQQAT------------------------------------------------
---QILELEKSLKEQQNSLRQL-EDNLAKEEAVQKFQVQYDRELEAAK-A-LMAKELEDA
KLKLQEDSALKFLATQKRFLEE----------------------GKEMSNQFSAEQEAVI
QELEGKHATELQLQNR----QLQEKQKQDTLALVAELRVKHQSEMDVLQDTLRREHRVHI
EAQLTESQVKHAAEIKELEDRHLANLDSLESSYLSEIQTMQNEHRQALERLRMGLEEQLQ
EKDSVE-KLFAEEMEKLKLKQIEELQLARDDLKVELAS--SHSEKLKAMAA---ELEDVH
KENLNVALQN---QRCLLEEENHKALDKLR---------------EEVLNMEEQHQKALQ
ELQNIHVTETEKQKEEYLE-----------------------------------------
------------------------------------------------------------
-----QLQELSKLREQQGHDQKLHDQIL-SLNAKIEETTSELEKLQQRRKRENQEGANLI
SMLRSDIELSQNERKTLQETNQRLLNLFGETIQAVIAMKSHIHKKIGHCLEGIDSFGE--
-ENYPLLGEGESSQDSCQLLDETLPGSDVVPECKVTTPGGHETLPECGKTLL----EHE-
---QISSVAEISSHLCESFFMNPEGTLECEQPVKKIYQSLGAAVDNLLEMILDSTKQLEE
TREIHSQFEKEFNRKNEEIAQVVKQHKELVECLNEESTAKNQLTVELHKAEGIIEGYRAE
KAALEEMLSQKEKSEHHLVVELENLKEQFQLLT------YERTKLGEERNLLLSQKEALA
AEAEEREVGVPVGSVVQKASGLLKKVECLAKEQTETKKQSEKDRSTLLSQMKVLEVELED
QLSQNQELAKKTAE-IMDLKQQIVSLDKHLRNQRQFMDEQAIEREHERDEFQHEIKKLEE
QLKYT--TKFQSVGEFRPNE-----NFESNTEMESLQRKLRDKSDELNELIIKKELADRQ
LVIQKDEI-------KILEETNAETLRKVSWLQEELDRLKKIEKELKQDREALQEQQLST
LIQISTLQ-SKLDEVKHLGPVESSP-EQDLKEQLKAEQDALHMKEREVLSLEEQLEQLKN
NLLHKNEDMVQLNLQLDL-QNDLMIASVKELREENTHLKAFL------------------
--------QDREQEIVHLNEQIKRLQHEVENAKDNEVVEKKNSEIEELKSLIENLQENQE
RLRRDKVEEVEQLHEVIEKLQKELSVFVPEDHEISDSQDSFNNP----KVENLQSELEKG
LLGFQEKLSDEKITRP----DSRLNELQEELKTVSIAKEALGQLLKEKQDQHKLQVESLK
QSLQNAEDNSTQQLSLL-----------------RTRLSLRDSEVELMTSRIQEFEDILR
AKETIISERELEIDAMSREKIAHFAQLEDVIAA-FSRLHCELEK--------RNTFFQ--
NEPPELQMLRSECVNLHLKLQMLNQKLVTYQMELDKHQACGSQCKAQ----------VQA
SVKQLDAL--STLKM----------------Q-----LRLQFRNED-------DHPEGDN
QILREQFE--AQHI-----------TE-----------EMSQEESEQEARKWPLPAA-SR
LPLDEE----------------------LVKNRP-SEDFQFQKANIIKQVKQLEEKLKHL
VSSATFKTSETQDVNHHQQVSE-SCEEVQV--LKNGLNNI------------SHSFQAIE
RSPLL------KDPILDLDRTS---------------------FNPF-------------
--E-------VVKSQDSASQK-EISSLPIQKRLGSQHAPLVSKTNL--------------
-------------------------------NSVSPIQEHSETSQHFTDAVMDVDLTLWS
SPEVIRKDS-LLGYQSDVRLTPFSDVISSHS---TDLGKRNSA-SSVFQN--IPGLLDCP
HDVIQEKTPQSLKPTPKLG--------------------NSYSADSGDAEAVISEKDDED
SILTPSEFQDDLRSTR--------P-IPERESD-GYDSSNSL------DL-AAKPNRVLK
R-------SEHPDASLEAYLRNCEMVQGFIH---SMKDK-EMQSRRMKTLLKMVHDESHQ
ILALSENEIPPQAARY-NQWNALFERFQRERQGLLEAVKSLRKHLTQ-TP----------
QEGAKDSLDICFDWRGEFLQAVEEVFE--KERDVLKNELQSNTWN-PESGDKKSLFKKLE
NIVKEQGE----EQKKVLEHLHVSDRSSLLSEIQALKAQLRMTHLQNQEKLQQLHEALTN
VEDHGNKQEYQLRRQVELLDYKL-------------------QQETCIANDLQKSLEGER
ERVAEIQELLVTEQTAVKDLKSELCECKQEKESLLKTLRELQKEVIRLR-----------
-----------------SLLESKEKDLFA-------------AIQEVQSE----------
--QLKGQDLQNTLEREQH---------------------QYMQREELKAKTLE-ELKSSL
DIQHTQN--NQLSIALKHEQMA-KENLKKELQIEY----------SRCEALLFQERNK--
-LLELQKTLETEK-NHSAEL------SEALNHERVLTEQLSKRANETCAL--KEAQ----
--SQQTLLRKLKEEKSRTMELQAALEKAQQQAIRSKKKLEAEIQMHR-EEIK--------
------------------------------------------------------------
-----------KEKERQLEVQHQRDEHKIKELQQM---LVKLEEKERNFASTKNCPEAAA
KTSCN---PDSNLGLAF---LPDSERFESQQLEKIRQQLLYVAVLLTNFINQTIDRTIND
WSTSNDKAVFSLLHTLEELKSELCIS----S--TPQKTAQVQI-SLVDSLLK-ENGSLTK
TLTTLTQEKVQLTQTVHKLE---KT--LKHHLQKGCGQMNKYVDRI-DGGPLQK-PEKNV
WKRQKI----SLKHAEPGPVKSVLRNEPSPVV-----R-TSNVKVEKLYLHFLRAESFRK
ALI-YQKRYLLLLIGGFQESEQETLSMISRLGVFPSKADHKA--IPPRPFTKFRTAVRVV
IAILRL--RFLVKKWQAVDRKGVL-TGGTELDTVPG-----EILEVTKQPL---------
-----------PDARDSPPTRDVSLCHTANG-IQVTKPQP--------------------
--APINRFWERSISSPSPVSEKSVACSQDPERSLTEYIHHLEIIQQRLGGAQSE--FAS-
KNPAIKRPKK--------

Query Results

"ENSGT00730000110871_1"

ENSGT00730000110871_1