Query Results 

------------------------------------------------------------
-------------MADSQEEDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVREKAVLETEKRLQFTEENQ----EEDECRTTVNKTRISPPQAP
--AKNADT-NSXXXLASMEKDAKERAKRRKENTVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

AEALKEKGKEALVRGDYETAILRYS
EGLEKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLY-NRAQAYIKLGDYQKALVDCDWALKXXXX------

ENSGT00730000110724_0_Linker_1_3 (289, 313)

XXXXXXXXXXXX
XXXXXXXX--SR

PF00515 // ENSGT00730000110724_0_Domain_3 (313, 325)

ECYQKILEINPQLQTQVKD---YLNQVNLQEKADLQEKEAQESLDSGK
NTAVTAKNLLETLSKPDQIPLFYAGGIEVLTEMMKDSTER--TLFRTH------NGFRII
SE----NEVLRRCFSTAGKDAVEETVCVSVLRLWQAVCS-ENXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXX--XFQVWFQASLP-GALPALTG-VLKRDPRV--TDTSALCQCIAIMGNL
SAEAATRRQMSASEEFGDACLDILAKCEED---VDLFREVIYTLLGLLMNLCLQSPVVSE
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXX-XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XX--XXXXXXXXXXXXXX--------X------XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXEPAK--------SNRLC-FEGGAAAPEVRSSGRWREMFYTP---VSISSV
EPAPSDRLQ--------------------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----TLIQELNSDDPIIQQKAVQQTEERLMLMEEA--R--EEDECRTTLNKTMISPPQAA
----NSDEINPEVFMASVENDAKERAERRRENKVLADALKENGNKAFAKGNYEMAILHYS
EGLDKMKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGEYQKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSM--SRQCYQKISEINPKLQTQVKE---YLHQVDLQEKTDFQEKEAHELLNTGK
NTAVTTKNLLETLSKPDQTPLFYAGGMEILTDVMKDCTEQ--TLFRTH------NGFSII
SN----NEVIRRCLSMAEKDMIEETVCVTVLKLWQAVCS-ENEENQRLLVLHPNTARLLP
SLLTSKVMAIQQQSLSLLL-QVTQTEHGRSLVISHLDMTRLLEALLSFLDFSDN-KASTA
IGLLTDLALEE--RFQVWFRANLP-GALPALTG-VLKRDPMV--TNSSALCRCIVIIGNL
SAEAAARRHMSSCEEFRDACLGLLAKCEDN---MDLYREVTYTVLGLVMNLCLQVPFASE
VWAVELSRRCLSLLNSQDGGILTRAAGVLSRTLSSSQ-KIIEEAVRAGVVKKMIKFLKIG
GQTASHYAIKILAICTNSCCEAREEVIKLDRKFSVLLKLLSSEDEVLMGNTAL-CLGNCV
EL--PNVASSLLKTDLVQ---------------VLLKLAGGDSQK--------TAVQLNA
GIALGKLCTVEPRFAAQLRE-----LHGLEILNSTMKYINDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKDKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------DGFSII
SD----NEVIRRCFSTAGKDAIEETVCVSVLKLWQAVCC-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPAVTS-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEEN---VALFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAVCPHRWE-MFHML--VFSLPRV
DPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MADDQERDLQRFLKNVDEIT---------------------------
----NLIQEMNSDDPVIQQKAVVETEKRLLLMEED--R--EEEGCRTTLNKTMISPPQAP
---ENTDEINPGSFLAAVEKDAKERAKKRRENKVLADALKEQGNEAFGKGDYEAAILHYT
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYQKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRECYRKILEINPKLQTQVKE---YLNQVTLREKADLQEKEAHEALESGK
NAAMTTKKLLETLSMPGQTPLFYAGGIEILTEMMKDCTER--TLFRTH------GGFHAI
SD----NEVIRRCLFAVGKDAVEEILCVAVLKLWQAVCS-ENEENQHLLVTHPDMPRLLP
SLLNSRVLLIQQQSLDLLS-QLTQTENGRNQVISHLDLTRLSEALLLFLDFSDK-KANIA
IRVLTDLVLEE--RFQGWFQANLP-GVLPALTG-VLKREIKL--TSPSALCQCIALLGNL
SAEPAARRHMMACEEFGDACLNLLVRCEED---MDLFREITYTLLGLIMNLCLQVSFISE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KTVEVALKAGVVKKMIKFLKMG
GETASRYAIKILAICTNSYHEAREEVMRLDKKFSILMLLLSSEDEVLVGNAAL-CLGNCM
EV--PNAAPCLLKTDIVQ---------------VLLKLAGSDSQK--------AAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIEILNSAMKHMSNS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEVT---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLQLMEEDQ----EVDECWTTLNKTVISPPQAP
--MKNVKEINSEAFLASVEKDAKERAKRRRENKVLADALKEEGNEAFVKGDYETAVLRYT
EGLQKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 323)

KAYFHMGKAH
LALKNYSM--SRECYKKILEINPMLQTQVKD---YLCQVDLREKAHLQEKEAHELLDSGE
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMMKDCTEQ--TLFRTH------NGFSTI
SD----NEVIRRCFSTAGKDAVEETVCVSVLKLWQAVCC-GNEENQRMLVMHPDRGRLLP
SLLASGVPAVEQQSLALLL-QLAQTENGRSLILGHLDLTRLLEALVSFLDFSDK-KANTA
MALLTDLALEK--RFQVWFQASLP-GVLPALTG-VLKRDPKV--TSSSALCQCIAIMGNL
SAEPATRAHMSACEDFGDACLGLMARCEED---VDLFREVIYTLLGLLMNLCLQAPFFSE
AWAVEVSRRCISLLNGQDGGILTRAAGVLSRTLSSSL-KIIEEAQRAGVVKKMIKFLKTG
GHTASRYAIKTLAICTNSHHEAREEVIRLDKKLSILMKLLHSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLVQ---------------VLLKLSGGDAKN--------TAVQLNA
GIALGKLCTAEPRYAAQSSLLR-----RGSA---ALEVLP----EETFHRL--VFSVSSV
EPP---------PPPPQSCNL--------------------

------------------------------------------------------------
-------------MAEEREKDLQKFLKDVDEIT---------------------------
----SLIQGMNSDDPDVQQKAVLETERRLLHTENGQ----GEDACRTTLNKTVISPPHPA
--TQNADDLNSXXXXXXXXXXXXXXXXXXXXXXXX

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

XXXLKEKGNEAFAEGDYETAVLHYS
EGLKKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF07719 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLGDYQKALVDCDWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAH
LALKNYGQ--SRECYQKILEIDPKLQPQVKD---CLHHVGLQEKAELQEKEAHESLASGN
NTAVTTRNLLETLSKPDQIPLFYAGGIEILTEMMAEGTER--TLFRTH------SGFSII
V--------TMRCFSSAGKDAVEETVCLSVLRLWQAVCR-ENEENQRLLLTCPGLGGLLP
CLLASGVVTLRQQSLALLL-QLAQTETGRSLILSHLDLTRLLTALLSFLDFSDK-KANTA
MGLLTDLALER--XXXXXXXXXXX-XXXXXXXX-XXXXXXXX--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXAKCEED---ADVFRDVMYTFLGLLMNLCVHAPFVSE
AWAMEVTRRCVVLLDSQDGGILTRAAGVLSRTLPTSL-KIVQEALQAGVLRKMIKFLKAG
GQTAPRYAIKTLAVCTNSCHEAREEVVRLDKKFHVLMKLLSSGDEILVGNAAL-CLGNCM
EV--PNAAAALLKTEVVK---------------VLFNTSGGDAQE--------TAVQVNA
GIALGKLCTADP------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----SLIQEMNSDDPFIQQKAVLDSEKKLLLMERE--Q--EEDGCRTTLNKTMISPSQTP
---ENADEMSPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAFIKLGDYQKALVDCDWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSK--AKECYQKIGEISPKLKAQVKE---HLNQVTLREKADLQEKEAQESLDSGK
NTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMADCTER--TLFRTY------GGFSTI
GD----HEVIRRCLFLTGKDAVEEVLCVSVLKLWQEVCV-DNEENQRLLVTHPDMARLLP
SFMTSRILVIQQQSLDLLL-QLTQTENGRNQVIKHLDMTQLCEALLSFLAFSDK-KANTA
IGILTDLALEE--RFQVWFQTNLP-DVLPALTG-ALNREPKI--TSPSALCQCIALLGNI
SAEPTARKHMIAHEEFGNACLDLLVKCEED---MDLFREITYTLLGLIMNLCLEITFLSE
MWVVKMSRKCLSLLNSKDGGILTRAAGVLSRTLSSSQ-TIVEEALTAGVVKKMIKFLRMG
GQTASRYAIKILAIFTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNAAL-CLGNCM
EV--PSAAPSLLKTDIVR---------------VLLKLAGSDSKE--------TGVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIQVLNSTMKHLNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDEWRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDEKCTKAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------NGFSII
SD----NEVIRRCFSTAGKDAVEETVCVSVLKLWQAVCC-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDRKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRKCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRFAAQLRK-----LHGLEILNSTMKYISDS------------------
-----------------------------------------

------------------------------------------------------------
------------MAKEKEERDLEKFLKNVDEIS---------------------------
----TLVQDLNSDDFDVCERAMDEAEKRLQLQEDQ-----EEDECRTILNKTMISPPQTK
--QVDVDDTNPDGFMKILEKDARERAKRRKENKSLANAFKEKGNEAFLKGDYEMAVHYYT
EGLKKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEEYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

NST

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSM--ARQCYQKILEINPKLQVQVKD---SLNKVDQKEKAELQEKLALQELKSGK
EAAVTTKNLLEALSNPEQIPLFYAGGVQLLTELMEDCTEK--TLFRTH------NGFSII
ND----NKVIKRCFATEEKDEIEEILCIAVLKLWHAVCT-GNEENQHLLLAHSDMDILLP
AFLTSKVPSIQQHTLSLLL-LFCQTENGRILVLSHMDLARLLQALVLFVNISEEKESRTA
MQLLTDLALEESNRFKTLVQTNLP-ALLTLISI-LLKNIPEI--AYPSTLLQCVAIMGNL
STDATIRKQMSDCEECWDACFRLMAKCEEN---VTLFRETLYATLGFMMNLSLESVSITE
VLAEQVSRKCVSLLNSEDGGILTRAAGVLSRVLSASM-KAVEEAVQAGLMKVMIKFLKAG
GQTASRYAIKILAVCTNINYLAREEVTRLDKKFCLLIKLLEAEDEIIAGNAAL-CIGNCV
EV--PGASSAVLKSDIVK---------------ILLKLAGGDAKE--------ASVQLNA
GIALGKLCTAEPRHTAHLEE-----LHGIEILNSTMKYIQKS------------------
-----------------------------------------

------------------------------------------------------------
--------------AQDTEADFQRFLRRVDDVA---------------------------
----NLLQGLKSPDSAVQEKAIAEAEKRLGEQGASREEEEEEEETRTTVNRTLINTSVR-
---AFPSEIKSALSLASIALEMDGREFDVLKALCCSAALKEQGNEAFRAGDFALAIQSYS
EGLQKLRDKQE

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAYLKLHEYEKAISDCEWAL------KCNRN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CI

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFLLGKAH
LALQHFAE--SRQCYEKMLQIDPQKEKLVKD---CVEEARLEEKRLRDEERAAREAQAGS
AAAFSIQELLQRLSSPGHDILYYTGGIRLLAEVVSSGTGQ--TLFRTN------NGFSLL
RS-----DAVRGALCAEEKSPAEEELCVSLLLLWRAACA-GNEENQRLLLAQPEVSAQLA
ELLSSGTARIQREALALISALYSEQQRGRRLLLR-QDLSRWLHILMAFVKCTDA-RAESA
INILSDLAGEE--RFQTQCRAMLSTD---------V--CAGQ--VELAQLARAVAVLGNL
CADVELRAQLARSGQCWQACLQLLVRLCCE--HTPGYQQCVFAVLGLMMNLLLESNGTIQ
DFAVPISGRCLALLNHQDGRIITRALGVLSRALPASP-AAVQEAVQGGAVRKMLKVLKAG
GQLTSSYAIKTLSTCIQSSRRAQEELQKRDK-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDEEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSADPAVQQKAVLETEKRLALAEVVH----NEDECRTALNKTMISPAQAP
--TKSADERNSXXXXXXXXXXXXXXXXXXXXXXXX

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

XXXLKERGNDAFVRGDYEAAILCYS
EGLKKLKDMKVLYTNRAQXXXXXXXXXXXXXXXXX------XXXCDEKC

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAH
LALKNYSE--SRECFQKILEISPKLQTQVKX---XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXX
XX----XXXXXXCFSTAGNHSGEEMVCVAVLQLWKAVCI-DNXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXLLEALVSFLNFSDK-KANSA
MGLFTDLALEE--RFQAWFQTNLF-GVLPALKS-VLKRDPKV--GSPTALCQCIAIMGNL
SAEAAIGKQLCASEEFGEACLGLMDRCEED---VDVFREVIYTLLGLLMNLCLQSPIISE
VWASKVSRRCLSLLNSQDGGLMTRAAGVLSRTLSSSL-IITGEALRAGVVKKMMKFLKTG
GQKASRYAVKILAVCTNSYHEAREEVVRLDKNFSILMKLLNSEDEILVGNAAL-CLGNCA
EV--PYTATSLLKTNIVQ---------------VLLKQAASDTQK--------TAVQLNA
GIALGKLCTVEPRAPAESSSVLC---SGGGFA--GPEPSPAHGWKVLN------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------ENVLEHLEKDAKERAERRKENTAM

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ANALKELGNKAFSKGDYETAVKCYS
EGVEKLRD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

QVLYTNRAQAFIKLEKYENAISDCQWAL------KCNEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF07719 // ENSGT00730000110724_0_Domain_2 (290, 325)

AKAYVHMGKAY
LGLKEYSE--ARKCYLKLLDVDPNLEKLVKD---YINTVDLQEANFKQEQVALEELKVAK
EDAVSVTQLLQKLSKADQIALYYSGGIRLLTEVVKDCTGQ--TLFRMN------SGFSII
GE----NKIILRSLDTVQAEADQIDLCESSLNLWKTVCC-GNAENQRLFFNNNSVVEKIP
SLLSSQVPEIQSKTLALVG-VFTDSDYGRSLLVQSMNPHSLLQILLECVRLSDG-RASTA
MEILQSLSQDENPKCKGKYDACDP-TTLPCFILILLKRTSKV--VNREVVLHCIGLLGHL
IEDGNIRGQVSESPECWDACMLFLDECSLL-AAEEEQRQVLSAILGLMFNLSLEINSAIQ
ERGIAITNKCMNLLNIKDGQVLMRCVGILSRVVPQCP-AAVEQVVQRGIIKKLVKLLKAG
GKRTSVFAAKVLAVCTKVDSVAKKDMIKYDKQFSTLLSLLHSEDETIVGNISL-CLGNCF
EV--PGAAASLLQTDILK---------------LLLTHAGGDAQT--------TKVQQNA
AIALGKLCTAEPRYMTQLRQ-----LNGIEILHSCMKYMKSL------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----SLIQEMNSDDPFIQQKAVLDSEKKLLLMERE--Q--EEDGCRTTLNKTMISPPQTP
---ENADEMSPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAFIKLGDYQKALVDCDWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSK--AKECYQKIGEINPKLKAQVKE---HLNQVTLREKADLQEKEAQESLDSGK
NTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMTDCTER--TLFRTY------GGFSTI
SD----HEIIRRCLFLTGKDAVEEVLCVSVLKLWQEVCV-DNEENQRLLVTHPDMARLLP
SFMTSRILVIQQQSLDLLL-QLTQTENGRNQVIKHLDMTQLCEALLSFLDFSDK-KANTA
IGILTDLALEE--RFRVWFQTNLP-DVLPALTG-ALKREPKI--SSPSALCQCIALLGNI
SAEPTTRKHMIAHEEFGNACLDLLVKCEED---MDLFRGITYTLLGLIMNLCLEITFLSE
MWVVKMSRKCLSLLNSKDGGILTRTAGVLSRTLSSSQ-TIVEEALTAGVVKKMIKFLRMG
GQTASRYAIKILAICTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNAAL-CLGNSM
EV--PSAAPSLLKTDIVR---------------VLLKLAGSDSKE--------TGVQLNA
GIALGKLCTAEPRFTAQLRE-----LHGIQVLNSAMKHLNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADYQEEDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQEKAVLETEKRLKFTEEDQ----EEDECRTTVNKTMISPPQAP
--TKNTDEINTEAFLASVEKDAKERAKRRRENKVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKEKGNEAFVKGDYETAILCYS
EGLEKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLGDYQKALVDCDWAL------KCDEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF07719 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAH
LALKNYSV--SRECYQKILEINPQLQTQVKD---YLNQVDLREKADLQEKEAQEALDSGT
NTAVTTKNLLEILSKPDQIPLFYAGGIEILTDMMKDCTER--TLFRTH------NGFSXX
XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXENQRLLVLCPDTGQLLP
SLLASRVPNIRQQTLALLL-QLAQTENGRSLIMGHLDLTGLLEALVSFLDFSDK-KANSA
MGLLTDLALEE--RFQVWFQASLP-DVLLALTG-VLRRDPKV--TNTSALCQCIAIMGNL
SAEAATRRQMSASEEFRDACLGLMAKCEEG---VNLFREVMYTLLGLMMNLCLQSPFVSE
VWAMEVSRKCLSLLNSQDGGILTRAAGVLSRTLVSSP-KIVEEALRAGVVKKMVKFLKAG
GQTASRYAVKILAICTNSYHEAREELIRLDKKLGVLMQLLGSEDEILVGNATL-CLGNCM
EV--PHVASSLLTTDIVL---------------VLLKLAGGDAQK--------TAVQLNA
GIALGKLCTAEPREPAKGSH-----LCFGG-GSAAPEVPSSRRWREMFTLV--SVAA---
EPP---------PPRHL------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----NLIQEMNSDDPAVQQKAVLETEKRLLLLERE--Q--EEDGCRTTLNKTMISPPRAP
---ENADDMNPEAFLASVEKDAKERAKRRRESRVLADALKEKGNEAYVKGDYETAIFYYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 287)

LYTNRAQAYIKLGDYEKALVDCEWAL------KCD

ENSGT00730000110724_0_Linker_1_2 (287, 291)

ERCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LAMKNYSK--SRECYQKIGEINPKLQTQVKE---SLNQVTLQEKADLQEKEARESLDSGK
NTAMTTKNLLETLSKPDQTPLFYAGGIEILTEMMTDCTER--TLFRTY------GGFSTI
SD----HEVIRKCLFSAGMDAVEEVLCVAVLKLWQAVCS-DNEENQRQLVIHPDMARLLP
SFMTSRILVIQQQSLALLL-QLTQTENGRNQVIKQLDMIRLCEALLSFLDFSDK-KSNTA
IGVLTDLALEE--RFQVWLQANLP-GVLPALTG-ALKREPKL--TSPSALCQCIALMGNI
SAEPTARRHMMSCEEFGDACLELLVKCEED---VDLFREVTYTLLGLIMNLCLEVPFISE
MWAMEMSRKCLALLNSQDGGILTRAAGVLSRTLSSSP-TIVEEALTAGVVKKMIKFLRMG
GQTASHYAIKTLAVCTNSCHPAREEVMRLDKKFSILILLLESEDEILAGNAAL-CLGNCM
EV--PSAASSLLKTNIIQ---------------ILLKLAGNDSQR--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIEILNSTMKHMNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADKEKDLQKFLKNVDEIS---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDECRTTLNKTMISPPQTA
--MKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 278)

LYTNRAQAYMKLEDYEKALVDCEWAL

ENSGT00730000110724_0_Linker_1_2 (278, 291)

KSFSFMQCDEKCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKG---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQ--TLFRMH------NGFSII
SD----NEVIRRCFSTAGNDAVEEMVCVSVLKLWQAVCS-RNEENQRVLVIHHDRARLLA
ALLSSKVLAIRQQSFALLL-HLAQTESGRSLIINHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPTTRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLKLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRFAAQLRK-----LHGLEILNSTMKYISDS------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------EGFLAALEKDAKERAKQRKRNERLANALKEKGNDAFRKGDYNTAAQRYT
DGLQKLKDV

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

PELYTNRAQAYLKMHEYGKAIGDCEWAL------KCNAK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF07719 // ENSGT00730000110724_0_Domain_2 (290, 325)

IKAYFLMGKAH
LALKHYDE--SRQCYQKLLQLDPQKKSLFKD---CMNEVNLEEKRMQEEDRAMKAFQSGK
DAALSIKDLLQKLNRPDQNILYYTGGIQVLIGVVKECECLMQSLFPWG------VVTRVD
ENNCTIRLCFVRGFCAGRKSTAEVDLCVSLLSLWQAVCA-GNEENQRLLLTHPDVNAQLL
ELLCSGVLEIQKETLALIA-LYSDNENGRRLLIRHQDLSRWLQILMMFVNSTDA-RASSA
MSILSDLIQEE--KFKAQCRLTFSTSVLPLFIQLLQ-ASAKL--VDQTALSCCIGIMGNL
CADAAIRVHMAECKECWQACLQLVDGCADV--GTPKYRECVFAVLGLMMNLLLESNSVIQ
CLAVDISGRCMSLLRDQDGRTVTRAIGVLSRILAASS-LAVEEAVKGGVVKKMIKFLKAG
GQTTSSYAIKTLSICTRSSRQAQEEVVKSDKKFSVLLKLLDSENEMIVGNAAF-CLGQCL
VV--PGAATSLLNSNIVM---------------ALLKHAGGDAAR--------TSVQENA
AIALGKLCVAEPRHIFQLRE-----LNGMAILNSSMKYVHSS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADYQEEDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVREKAVLETEKRLQFTEGDQ----VEDECRTTVNKTMISPPQAP
--MKDADEINTAAFLASLEKDAKERAKRRRENKVLADALKEKGNEAFVRGDYETAILCYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYRKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRECYQKILEINPQLQTQVKE---YLNQVDLREKADLQEKEAQESLDSGK
NSAMTTKNLLETLSKPDQIPLFYAGGIEILTEMMKDCTER--TLFRTN------NGFSII
SE----NEVIRRCFSTAGKDAVEETVCLSVLRLWQAVCS-ENEENQRLLVLRPDTGPLLP
SLLASSVPAIQQQSLALLL-QLAQTENGRNLIIGHLDLPRLLEALVSFLDFSDK-KANSA
MGLLTDLALQE--RFQVWFQTSLP-DILPVLTG-VLKRDPKV--TNISALCQCLAIMGNF
SAETAAQRQMSASEDFGAACLGLMAKCEED---ADLFRDVTYALLGLVMNLCLRSPFVSE
VWAVEVSRKCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMIKFLKAG
GQTASRYAVKILAICTNSYQEAREEVVRLDKKLGVLMQLLDSEDEILVGNAAL-CLGNCM
EV--PHAASSLLSTDIVP---------------ILLKLAGSGAPQ--------TAPPLNG
GPQAEASEGTQHG-TGVFPGTSSHRLLSAQLLQSPLSSPPPSPRTSPTSLS--CLSISSA
FPE---------TSL--------------------------

------------------------------------------------------------
------------MAKEEEERDLEKFLKNVDEIX---------------------------
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXGFMEVLEKDARERAKRRKENKSL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ANALKEKGNEAFLKGDYRMAVKHYS
EGLGKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLEDYEKALVDCDWAL------KXXXXXXXXXXXXXXXX
XXXXXXXX--SRQCYQKILEINPKLQTQVNX---XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXX--XXXXXXXXXXXXXXXXXX
XX----XXXXXXCFVTEGKGEIEEALCVAVLKLWQAVCN-GNEENQRLLLTHSDMDVLLP
FFLTSKVPSIQQYSLSLLL-LLCQTQNGRILVLNHVDLTRLLQAFVAFVSNSEEEEARMA
MQLLTDLALED--RFKTWVQTNLC-ALLTLIRI-LXXXXXXXX-XXXXXX--XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXVKCEENENKNELFQENLYATLGLMMNLSLESLSITE
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXAG
GQTASRYAIKILAVCTNIYYEAREEVTRLDKRFSLLVKLLEAEDEIIVGNAAL-CIGNCV
EV--PGAASSLLKSDIVK---------------ILLKLAGGDVKE--------GSVQLNA
GIALGKLCTAEPRAPAESHHLLCFREEGSVSAPEEF----SFHWEDRLDPAHSIFSAGRA
GPPSSRYLQ--------------------------------

------------------------------------------------------------
-------------MADYQEEDLQKFLKDVDEIT---------------------------
----NLIQDMNSDDPVAQEKAVLKTEKRLLLTEEDQ----EEDGCRTTLNKTMISPPQAL
--TKNADEINSEAFLAFVEKDAKERAKRRRENRVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

TDALKEKGNEAFVRGDYETAILCYS
EGLEKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLGDYQKALVDCDWALKXXX------XXXXXXXXXXXXX
XXXXXXXX--SRECFQKILEINPQLQTQVKD---YLNQVDLRQKADLQEKEAHELLDSGK
NTAVTTKNLLETLSKPDQNPLFYAGGIEILTEMMKDCTER--TLFRTQ------NGFSII
SG----NEIIRRCFSTAGKDAMEETVCVSVLRLWQAVCS-ENXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXLLEALVSFLKFSDK-KANSA
MGLLIDLALEE--RFQVWFQANLP-SVLPALTG-VLKRDPRV--TNTLALSQCIALMGNL
SAEAATRRQMSASEEFGNACLSLMARCEED---VDLFREVIYALLGLMMNLCLQSPFVSE
IWTMEASRRCMSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMIKFLKTG
GQTASRYAVKTLAICTNSYHEAREEVTRLDKKFSVLKELLSSEDEILVGNAAL-CLGNCM
EV--PQAASSLLKTDIVQ---------------VLLKLAGSDAQK--------TAVQLNA
GIALGKLCTAEPRVPAESSNLL----CFGGF--AAPEAPSSCRWEMF--YI--VFSIPSA
EPTPKSRRF--------------------------------

------------------------------------------------------------
-------------MADDHEKDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPLVQQKAILETEKRLRFTEEVR----EEDGCRTTLNKTVISPPQAS
--TKNADEINSEAFLASMELDAKERARRRRENKVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKEKGNEAFARGDYKAAIVCYS
EGLDKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYLKLGDYQKAVVDCEWAL------KCDEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAH
LALKNYSV--ARECYQKILEIKPRLQTQVKD---YLNQVNLQEKADLQEKEAHRSLDSGK
NTAVTVRNLLETLCKPDQTPLFYAGGIEILTEMMKDDTER--TLFRTH------NGFSLI
SE----NEVLRRCFSRARKDAVEEMVCLSVLRLWQAVCT-GNEENQRLLLECPDVGRLLP
SLLATRALSVRQQSLALLL-QLAQTDHGRSLVISHLDLTRLLEALVSFLDFSDK-EANSA
MGLLTDLALEE--RFQVWFQANLP-GVLLALTG-VLKRDPLV--TNASALCRCIAIMGNL
SAEAAVRRQMSACEEFREACLGLMARCEED---VDLFREVLYTLLGLVMNLCLQSPIVCE
VWALEVSRRCMFLLNSQDGGILTRAAGVLSRTLSSSQ-KIVEEALRAGVVKKMIKFLKTG
GQTASRYATKTLAVCTNSCHEAREEVIRLDKKFGILMKLLSSEDEIVVGNAAL-CLGNCM
EV--PYAAPPLLKTDIVQ---------------VLLRHAGSDAQK--------TAVQLNA
GIALAKLCTAEPRFAAQLQE-----LHGLEILSSTMKYIVD-------------------
-----------------------------------------

------------------------------------------------------------
-------------MAEYQDEDLQKFLKKVDEIT---------------------------
----NLIQDMNSDDPEVQQKAVLETERHLQLLEGDLEE--EEDACRIAMDKTLISPPQAP
--KENEDGINPEAFLASMEKDAKERAKRRMENKVLADALRVKGNEAFSKGDYNLAIQHYS
EGLEKMKDMKVLYTNRAQAYSKLGDYQKVLADCDWAL------KCDEAYT

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYRE--ARECYEKILEINPKLQTQVKE---YLMQVNLQEKVDLQEKEAHEILALGK
NTAVTTKNLLETLSRPDQAPLFYAGGMEILTEMMKQCTER--TLFRTH------SGFSII
ND----NEVLRRCLLAEKKDAVEETVCVSVLKLWQAVCY-ENEENQRFLVMHPDRAGLLL
SFLTSPVLAIRQQSLTLIL-QLAQTENGRSLIISHLDLTQLLEALLLFLEFSDK-KANTA
MGLLTDLFLEE--RFQAWFQASLP-DVLPMLTG-VLKRDPML--TSTSAFCQCVSMMGNL
SAKPAARRHMWAYEKFPDACLGLLVTCEED-----LFRDIIYTLLGLVMNLCLQVPFVSE
AWAMEVSRKCLSLLNSQDGGILTRAAGVLSRTLPSSL-KIVQEALKAGIVKKMIKFLKTG
GQSASRYAMKILAVCTNSFHEAREEIMKLDRKFSVLVKVLNSKDEIVVGNAAL-CLGNCM
EV--PSAASCLLKTDLVP---------------ILLRLTASDTQR--------PSVQLNA
GIALGKLCTAEPRFAIQLKE-----HHGIEILNSVMKYINNS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADYQEEDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVREKAVLETEKRLQFTEGGR----EEDECRTTVNKTVISPPQAP
--TKDTDEINTEAFLASLEKDAKERAKRRRENKVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 244)

ADALKEKGNAAFVRGDYETAILCYS
EGL

ENSGT00730000110724_0_Linker_0_1 (244, 252)

EKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYRKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRECYQKILEINPQLQTQVKE---YLNQVDLREKADVQEKEAQESLDSGK
NSAVTTKNLLETLSKPDQIPLFYAGGIEILTEMMKDCTER--TLFRTN------NGFNII
SE----NEVIRRCFSTAGKDAVEETVCLSVLRLWQAVCS-ENEENQRLLVLRPDTGPLLP
SLLASRVPAIRQQSLALLL-QLAQTENGRSLIIGHLDLIRLLEALVSFLDFSDK-KANSA
MGLLTDLALQE--RFQAWFQTSLP-DVLPVLTG-VLKRDPKV--TNISALCQCLAIMGNF
SAEAAAQRQMSASEDFGAACLGLMAKCEED---ADLFRDVMYALLGLVMNLCLQSPFVSE
VWAMEVSKKCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMIKFLKAG
GQTASRYAVKILAICTNSYQEAREEVLRLDKKLGVLMQLLDSEDEILVGNAAL-CLGNCM
EV--PRAASSLLSTDIVP---------------VLLKLAGSDAQQ--------TAVQLNA
GIALGKLCTAEPRFAALLRE-----LHGMEILNSTMKYVESS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADREKDLQKFLKNVDEIT---------------------------
----NLIQKMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDDCRTTLNKTMISPPQTT
--MKSAEEIDSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAKGDYETAILCYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADHQEKEAHTLLDSGK
NTAVTTRNLLETLSKPDQIPLFYAGGIEILTEIIKECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTARKDAAEETVCVSVLKLWQTVCS-GNEENQRVLVMDPDRARLLA
ALLSSRILAIRQQSLALVL-QLAQTESGRSLVISHLDLTRLLEALVSFLDFSDK-EADTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKRDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMTACEEFGNGCLSLMARCEED---VDLFREVIYTLLGLLMNLCLQAPFGSE
VWTVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMIKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDNKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLVQ---------------VLLRLSGSDTQK--------TAVQVNA
GIALGKLCTAEPRYVVD-----------WEP-----GSLSSRRWEEMFHML--VFSLSRV
DPP--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MITCVL
---QNADEMNPDAFLACVEKDAQERAKRRRENRILADALKEKGNEAFAKGDYETAILHYS
KGLEKLKDMQV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 286)

LYTNRAQAYIKLGDYQKALVDCDWAL------KC

ENSGT00730000110724_0_Linker_1_2 (286, 291)

DDKCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRECYQKILEINPKLQSQVKE---YLNQVDLQEKVDLQEKEALESLDSGK
NTAMATKNLLETLSKPGQTPLFYAGGIEILTEMMKDCKPE--TCVVS-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

----------------------------------------------MATP---------Q
TLRNLRPPAMAALPDPQQEADFQRFLRRVDDISECGSGVGETDGRGKGKWKTPRSPLPYR
VSPGRLVQGLSSADSAVRDAAIAETDRRLRERQGSE-------QSAAAADRTVINTRDPV
RGSVNAEAVHTEGFLAALEKDAKERAKRRKRNERLANALKEKGNDAFRKGDYSTAAQRYT
DGLQKLKDMP

PF00515 // ENSGT00730000110724_0_Domain_1 (251, 285)

ELYTNRAQAYLKMHEYGKAIDDCKWAL------KVRSVCCSVVRWSVCVQ
LSVWKWHGNGSGNMLG---DI---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLVEEDQ----EEDDCRTTLNKTMISPPQTT
--MKSTEEIDSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAKGDYETAILRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADHQEKEAHKLLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEIIKECTEQ--TLFRIH------NGFSII
SD----NEVIRRCFSTAGKDAAEETVCVSVLKLWQTVCS-GNEENQRVLVMDRDRARLLA
ALLSSRVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EADTA
MGLFTDLALEE--RFQVWYQANLP-GVLPALTG-VLKRDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMTACEEFGDGCLSLMARCEED---VDLFREVIYTLLGLLMNLCLQSPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVIKKMIKFLKTG
GETASRYAVKILAICTNSYHEAREEVVRLDNKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLVQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAESSH-----LRFGGR-----CSLSSHRWEEMFHM----FSLYSV
DPP---------CHCPNFVTS--------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----TLIQELNSDDPVIQQKAVHQTEKRLMLMEEA--Q--EEDECRTTLNKTMISPPQAA
----NADELKPEAFLASVEKDAKERAKRRRENKVLADALKEQGNKAFAKGDYETAILHYN
EGLDKMKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYQKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSM--SRQCYQKISEINSKLQTQVKE---YLHQVDLQEKADFQEKEAHELLDLGK
NTAVTTKNLLETLSKPDQTPLFYAGGMEILTDVMKDCTEQ--TLFRTH------NGFSII
SD----NEVIRRCLSIAEKDMIEETVCVTVLKLWQAVCS-ENEENQRLLVLHPNIVRLLP
SLLTSKVMAIQQQSLALLL-QVTQTEHGRSLVISHLDMTRLLEALLSFLDFSDK-KASTA
IGLLTDLALEE--RFQVWFQANLP-DALFAFTG-VLKRDPMV--TNSSALCRCIAIMGNL
SAEPATRRHMLACDEFRDACLGLLARCKDD---MDLYREVTYTLLGLMMNLCLQVPFVSE
VWAVELSRRCLSLLNSQDGGILTRAAGVLSRTLSSSQ-KIIKEAVRAGVVKKMIKFLKTG
GQTASHYAIKILAVCTNSYCEAREEVIRLDKSK---------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----SLIQEMNSDDPFIQQKAVLDSEKKLLLMERE--Q--EEDGCRTTLNKTMISPPQTP
---ENADEMSPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAFIKLGDYQKALVDCDWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
VALKNYSK--AKECYQKIEEINPKLKAQVKE---HLNQVTLREKADLQEKEAQESLDSGK
NTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMADCTER--TLFRTY------GGFSTI
SD----HEVIRRCLFLTGKDAVEEVLCVSVLKLWQEVCV-DNEENQRLLVTHPDMARLLP
SFMTSRILVIQQQSLDLLL-QLTQTENGRNQVIKHLDMTQLCEALLSFLAFSDK-KANTA
IGILTDLALEE--RFQVWFQTNLP-DVLPALTG-ALNREPKI--TSPSALCQCIALLGNI
SAEPTARKHMIAHEEFGNACLDLLVKCEED---MDLFREITYTLLGLIMNLCLEITFLSE
MWVVKMSRKCLSLLNSKDGGILTRAAGVLSRTLSSSQ-TIVEEALTAGVVKKMIKFLRMG
GQTASRYAIKILAICTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNAAL-CLGNCM
EV--PSAAPSLLKTDIVR---------------VLLKLAGSDSKE--------TGVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIQVLNSTMKHLNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPETA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------NGFSII
SD----NEVIRRCFSTAGKDAVEETVCVSVLKLWQAVCC-RNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLIRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTD-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAGSPHRWEEMFHML--VFSLSSV
DPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIS---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDECRTTLNKTMISPPQTA
--MKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILCYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDEKCTKAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEARELLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRTH------NGFSII
SD----NKVIRRCFSTAGKDAVEETVCVSVLKLWQAVCS-GNEENQHVLVMHHDRARLLA
ALLSSKVLAIRQQSLALLL-QLTQTESGRSLIINHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLDLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGMVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSMMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLKLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRFVAQLRK-----LHGLEILNSTMKYISDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLTEEDQ----EEDECRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------NGFSII
SD----NEVIRRCFSTAGKDAVEETVCVSVLKLWQAVCC-GNEENQRVLVMDPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVAKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAVSPHRWEEMFHML--VFSLSSV
VPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIS---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDECRTTLNKTMISPPQTA
--MKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTAGNDAVEEMVCVSVLKLWQAVCS-GNEENQRVLVMHHDRARLLA
ALLSSKVLAIQQQSFALLL-QLAQTESGRSLIINHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPTARRHMAACEEFGDGCLSLLARCEKD---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLKLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAESSH-----LQFGGESA-APEALSPHRWEEMFHML--VFSLSSV
DPP---------PPPPQTCYP--------------------

------------------------------------------------------------
-------------MDADQEKDLRKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQIQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDRIPLFYAGGIEILTEMIKECTEQ--TLFRMH------DGFSII
SD----NEVIRRCFSTAGKDAIEETVCVSVLKLWQAVCC-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEEN---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDKKLSMMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSR-----LQFGGESTA-PEAVSRHRWEEMFHVL--VFSLPRV
DPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----TLIQEMNSDDPVVQQKAVLETEKKLLLLEEH--Q--EEDGCKTTLNKTMISPPQAP
--AENADELSPEAFLASVEKDAKERAKRRRENKVLADALKEEGNEAFVKGDYETAILHYS
QGLEKLKDMKV

PF13181 // ENSGT00730000110724_0_Domain_1 (252, 269)

LYTNRAQAYIKLGDYQK

ENSGT00730000110724_0_Linker_1_2 (269, 291)

ALGDCDWAL------KCDEKCT

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSA--SRECYQKILEINPKLQTQMKE---YLNQVHLQEKADLQEKEAHELLDSGK
DTAVTTKNLLESLSKPDQMPLFYAGGMEILTEMMKDCTER--TLFRIH------GGFRII
SD----NEVIRRCFSMTGKDVVEETICVSVLKLWQAVCS-ENEENQRLLMMYPDWARLVP
SLLTSRVLAIQQESLALLV-QLAQTENGRSLVISHLDLTRLLEALLSFLDFLDK-KANIA
MGLLTDLALDE--RFQVRFQANLP-DALPALIG-VLKRDPKV--TNASALCQCIAIMGNL
SAEPATRKHMAACEDFGDACLGFLARCEED---LDLFREITYTLLGLIMNVCLQVPFVSE
VWAMEVSRRCLTLLHCQDGGILTRAAGVLSRTLSSSL-NIIEEAVRTGVVKKMIKFLKTG
GQTASHYAIKTLAICTNSYHEAREEVIRLDKKFNILMKLLSSDDEILVGNAAL-CLGNCM
EV--PKIASSLLKTDLVL---------------VLLKLAGSDSQN--------SAVQLNA
GIALGKLCTAEPRFTAQLRE-----LHGMEILNSTMKYIQDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDEESDLQRFLENVDEIT---------------------------
----NLIQEMNSDDPIIQQKAVLETEKRLLLMERD--P--EEDGCRTTLNKTTISPPQAP
---ENTDEMNPEAFLASVEKDAKERAKRRRESRILADALKEKGNEAFIKGDYETAILYYS
EGLGKLKDMQV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGEYEKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSK--SRECYQKITEINPKLQTQVKE---YLNQVILREKADLEEKEARESLDSGK
NTAMTTRNLLETLSKPDQTPLFYAGGIEILTEMMTDCTER--TLFRTH------DGFSTI
ID----HEIIRRCLFSEGKDAVEEVLCVAVLKLWQAVCG-DNEENQRLLVTHPDMARLLP
SFMTSSITVLRQQSLALLL-QLTQTENGRTQVIRHLDLTRLCEALLSFLDFSDK-KANTA
IGLLTDLALEE--RFQVWFRANLP-GVLPALTG-VLKREPML--TSPSALCQCIALMGNI
SAEPTARRHMVACEEFRDACLNLLAKCEED---MDLFKEVIYTLLGLIMNLCLEGPFISE
MWAVKMSQKCMSLLNSQDGGILTRAAGVLSRTLSSSL-TIVEEALRAGVLKKMIKFLKMG
GQTASRHAIKTLAVCTNNYHPAREEVMRLDKKFNILIMLLDSEDEILVGNAAL-CLGNCM
EV--PRAASSLLKTDIVQ---------------TLLKLAGSDSQK--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIEILSSTMKHMNDS------------------
-----------------------------------------

------------------------------------------------------------
------------MKTGSVDNDLKKFNCEREEKA---------------------------
----NLIQGMNSDDPVVRQKAVQETEKRLLLTEKDQ----EEDECRTTLNKTMISPPQAF
--AKNADEINSAAFLVSLEKDAKERARRRRENKVF

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKEKGNEAFAKGDYETAVLCYS
EGLKKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLGDYQKALVDCDWAL------KCDEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAN
LALRNYSA--SRECYQRILEIDPKLQTQVKD---CLNQVDLQEKAELQEKEAHELLNLGK
NTALMTKNLLETLSKPDQLPLFYAGGIEILTEVMKECKPV--WVRELTRWQWFFFFLNLI
LL----SLLYSRCFSTAGNDAVEETVCVSVLRLWQAVCG-GNEENQRLLVTCPDMGELLP
SLLDSRVMTIQQQSLALLL-QIAQTENGRSLILSHLDLTQLLEALVSFLDFPDK-KANTA
MELLTDLALEK--RFQVWFQANLP-GVLPTFIG-VLKRNAKI--TNPSALCQCIAVMGNL
STDAPTRRQMASCEEFGDACLGLMAKCEED---MDLFREVMYTLLGLLMNLCLDSPFVSE
AWAVEVSRRCMALLNSQDGGILTRAAGTLSRTLPSSL-KIVEEALRAGVVKKMMTFLKTG
GQTASHYAIKTLAICSNSCHEAREEVIRLDKKFSVLMKLLSSEDDILVGNAAL-CLGNCM
EV--PNAASSLLKTEIVK---------------ILLKHAGGDAQK--------TAVQLNA
GVALGKLCTAEPRYAAQLGE-----LHGLEILSSTVKHIKD-------------------
-----------------------------------------

------------------------------------------------------------
-------------GDAGQ---ELGIQKAVTSLS---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDECRTTLNKTMISPPQTA
--MKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 278)

LYTNRAQAYMKLEDYEKALVDCEWAL

ENSGT00730000110724_0_Linker_1_2 (278, 291)

KSFSFMQCDEKCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTAGNDAVEEMVCVSVLKLWQAVCS-GNEENQRVLVMHHDRARLLA
ALLSSEVLAIRQQSFALLL-QLAQTESGRSLIINHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCITVMGNL
SAEPTTRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDVLQ---------------VLLKLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRFAAQLRK-----LHGLEILNSTMKYVSDS------------------
-----------------------------------------

------------------------------------------------------------
---------------MADEEDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPRIQQKAILETEQRLLYTEEVP----EEDGCRTTLNKTTINRSQAP
--MENADEINSEAFLASMELDAKERARRRRENRV

PF13414 // ENSGT00730000110724_0_Domain_1 (215, 286)

LADALKDKGNKAFARGDYNAAVLCYS
EGLNKVKDMKVLYTNRAQAYLKLGDYQKAIVDCEWAL------KC

ENSGT00730000110724_0_Linker_1_2 (286, 291)

DEKCT

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYNM--SRECYQKILEISPKLQTQVKD---SLNQVNLQEKADLQEKEAQRLLDSGK
HAAVTVKNLLETLCKPDQNPLFYAGGIEILTEMMKDCTEQ--TLFRTH------NGFSII
SE----NEVVRRCFSATGKDVVGETVCVSVLRLWQAVCS-GNEENQRLLLLCPNLGRLLP
SLLATRLLTVRQQSFALLL-QLTQTDYGRSLVISHLDLTRLLEALVSFLDFSDK-EANSA
MALLTDLALDE--RFRVWFQANLP-GVLPVLTG-VLERDPMV--TSPSALCRCIALMGNL
SAEAAVRRQMFASEEFREACLGLMARCEED---MDFFREVMYTLLGLVMNLCLQSPFVYE
VWAVEVSRKCMFLLNSQDGGILTRAAGVLSRTLSSSR-KMVEEALRAGVVKKMIKFLKTG
GQTASRYAIKTLAVCTNSHYEAREEVIRLDKKFGILMKLLSSEDEMVVGNAAL-CLGNCM
EV--PYAASSLLKTDVVQ---------------VLLKHAGGDAQE--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIEILNSTMKYVADP------------------
-----------------------------------------

------------------------------------------------------------
-------------MADYQEEDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVREKAVLETEKRLQFTEGDQ----VEDECRTTVNKTMISPPQAP
--MKDADEINTEAFLASLEKDAKERAKRRRENKVLADALKEKGNEAFVRGDYETAILCYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYRKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRECYQKILEINPQLQTQVKE---YLNQVDLREKADLQEKEAQESLDSGK
NSAMTTKNLLETLSKPDQIPLFYAGGIEILTEMMKDCTER--TLFRTN------NGFSII
SE----NEVIRRCFSTAGKDAVEETVCLSVLRLWQAVCS-ENEENQRLLVLRPDTGPLLP
SLLASRVPAIQQQSLALLL-QLAQTENGRNLIIGHLDLPRLLEALVSFLDFSDK-KANSA
MGLLTDLALQE--RFQVWFQTSLP-DILPVLTG-VLKRDPKV--TNISALCQCLAIMGNF
SAETAAQRQMSASEDFGAACLGLMAKCEED---ADLFRDVTYALLGLMMNLCLRSPFVSE
VWALEVSRKCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMIKFLKAG
GQTASRYAVKILAICTNSYQEAREEVVRLDKKLGILMQLLDSEDEILVGNAAL-CLGNCM
EV--PHAASSLLSTDIVP---------------ILLKLAGSDAQQ--------TAVQLNA
GIALGKLCTAEPRFAAVLRE-----LHGMEILNSTMKYVENS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADNQDKDLQRFLKNVDEIA---------------------------
----NLIQEMNSDDLAVQQKAFVETEKRLLHMKEEE----EEDGCRTALNKTMISPPQAP
--TENTDELNAXXXXXXXXXXXXXXXXXXXXXXXXXXXLKEQGNEAFGKGDYDTAVLRYS
EGLEKLKDM

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLGNYQKALVDCDWAL------RCDDK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF07719 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFLMGKAH
LALKNYST--SRECYQKILEINSKLQTQVKG---YLHQVDLREKADLQEKEAHEHLDSGR
NTAVSTKNLLVTLSKPGQTPLFYAGGIEILTEMMQGCTEQ--TLFRTH------NGFSVI
SD----NEVLRRCIFVAEKDAIEETACVSVLKLWQAVCR-WNEENQRLLVSHPEWARLLP
SFLASRILVIRQQSLALLL-QIAQTGNGRDLIISHLDLTXXXXXXXXXXXFPDK-KATNA
TRLLTELALEE--RLQDWLRVNLP-GVLPALTS-ILXXXXXX--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXAKCEEG---EIRFREVTYMLLGLMMNLCLQTPYVSE
SWAAEVSTQCLSLLKSQDGGILTRAAGVLSRTLPSSL-KVTEAALRAGVVKKMIKFLKTG
GPTASHYAIKILAICTNTCHSAREELVRLDKHFSILLQLLNSEDEVLAGNAAL-CLGNCM
EV--PQVATSLLQTDLVQ---------------VLLKLAGGDAQQ--------TAVQLXX
XXXXXXXXXXXXXLGGGSA---------------APELLYPHRWKRPTPHF--PYF----
-----------------------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----SLIQEMNSDDPFVQQKAVLDSERKLLMLERE--Q--EEDGCRTTLNKTMISPPQAP
---ENAGEMSPDAFLASVEKDAKERAKRRQENRVLADALKEKGNEAFVKGDYETAIFFYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAFIKLGDYQKALVDCDWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSK--SKECYQKIGEINPKLKAQVKE---HLNQVTLREKADLQEKEAQESLDSGK
NTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMTDCTER--TLFRTY------GGFSTI
SD----HEVIRRCLFLTGKDAVEEVLCVSVLKLWQEVCV-DNEENQRLLVTHPDMARLLP
SFMMSRILVIQQQSLALLL-QLTQTENGRNQVIKHLDMTQLCKALLSFLDFSDK-KANTA
IGILTDLALEE--RVQVWFQTNLP-DVLPALTG-ALKREPKL--SSPSALCQCIALLGNI
SAEPTARRHMIAHEEFGNACLDLLVKCEED---MDLFREITYTLLGLIMNLCLEVPFSSE
MWFMKMSRKCLSLLNSKDGGILTRAAGVLSRTLSSSQ-TIVEEALAAGVVKKMIKFLRMG
GQTASRYAIKILAICTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNAAL-CLGNCM
EV--PSAALSLLKTDIVR---------------VLLKLASSDSQK--------TGIQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIQVLNSTMKHLKDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADYQEKDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVQEKAVLETEKRLQFMEQDR----EEDECRTTVNRTVISPPQAP
--AKNADEISSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFGKGDYETAISCYS
EGLEKLKDMKV

PF13181 // ENSGT00730000110724_0_Domain_1 (252, 284)

LYTNRAQAYIKLGDYRKALTDCDWAL------

ENSGT00730000110724_0_Linker_1_2 (284, 291)

KCDEKCT

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSE--SRECYQKILEINPQLQTQVKG---YLNQVDLREKADLQEKEAQDLLDSGK
DTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMMKDCAER--TLFRTH------NGFSII
SD----NEVIRRCLSTAGKDAVEETVCVSVLRLWQAVCS-ENEENQRLLVMHPTRGQLLP
ALLASRVPTIQEQSLALLL-QLAQTENGRGLIISHLDLTRLLEALVSFLDFSEK-KANSA
MALLTDLALEE--RFHVWFQASLP-GALPALAA-VLKRDPRV--TSTSALCQCIAILGNL
SAEPAARRQLFASEEFGDACLGLMAKCEED---MDLFREVMYTLLGLMMNLCLQPSLVSE
VWAMEVSRKCLSLLNSPDGGILTRAAGVLSRTLSSSL-TIVEEALRAGVVKKMIKFLKAG
GQTASRYAIKILAICTNSYHEAREEVIRLDKKLSVLMQLLGSEDEILVGNAAL-CLGNCM
EV--PLVASSLLTTDIVQ---------------VLLRLAGGDAQK--------TAVQLNA
GIALGKLCTAEPRFAALLRE-----LHGMEILNSTMKHVDRS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----NLIQEMNSDDPAVQQKAVLETEKRLLLLERE--Q--EEDGCRTTLNKTMISPPRAP
---ENADDMNPEAFLASVEKDAKERAKRRRESRVLADALKEKGNEAYVKGDYETAIFYYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 287)

LYTNRAQAYIKLGDYEKALVDCEWAL------KCD

ENSGT00730000110724_0_Linker_1_2 (287, 291)

ERCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LAMKNYSK--SRECYQKIGEINPKLQTQVKE---SLNQVTLQEKADLQEKEARESLDSGK
NTAMTTKNLLETLSKPDQTPLFYAGGIEILTEMMTDCTER--TLFRTY------GGFSTI
SD----HEVIRKCLFSAGMDAVEEVLCVAVLKLWQAVCS-DNEENQRQLVIHPDMARLLP
SFMTSRILVIQQQSLALLL-QLTQTENGRNQVIKQLDMIRLCEALLSFLDFSDK-KSNTA
IGVLTDLALEE--RFQVWLQANLP-GVLPALTG-ALKREPKL--TSPSALCQCIALMGNI
SAEPTARRHMMSCEEFGDACLELLVKCEED---VDLFREVTYTLLGLIMNLCLEVPFISE
MWAMEMSRKCLALLNSQDGGILTRAAGVLSRTLSSSP-TIVEEALTAGVVKKMIKFLRMG
GQTASHYAIKTLAVCTNSCHPAREEVMRLDKKFSILILLLESEDEILAGNAAL-CLGNCM
EV--PSAASSLLKTNIIQ---------------ILLKLAGNDSQR--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIEILNSTMKHMNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADNQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQKAVLKTEKKLLLMEEDQ----EDDECRTTLNKTMISPPQAT
--VKSAEEINSEAFLASVEKDAKERAKRRRENRVLADALREKGNQAFMEGDYETAVLHYS
EGLAKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYEKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRECYWKILELNPKLQTQVKD---YLNQVDLREKADLQEKEAHELLNSGK
NMAVTTRNLLETLAKLDQIPLFYAGGIEILTEMMKDCTEQ--TLFRTH------NGFSVI
SD----NEVIRRCFSTSEKDIVEETVCVSVLKLWQAVCS-GNEENQRVLVMHPDRGRLLP
SLMASRVLAIRQQSLALLL-QLAQTENGRSLIISHLDLTRLLEALVSFLDFSDK-KANTA
MGLLTDLALEE--RFRVWFQASLP-GVLPALIG-VLKKDPKV--TNSSALCQCIAIMGDL
SAEPAIRRHMSACEEFGDACLGLMARCEED---VDLSRDIIYTLLGLMMNLCLQAPVVSE
VWAMEVSRRCMTLLNSQDGGILTRAAGVLSRILPSSL-RIVEEALRAGMVKKMMKFLKTG
GQTASRYAIKTLAICTNSYHEAREEVIRLDTKLSILMKLLRSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLVQ---------------VLLKLAGSDTKK--------TAVQVNA
GIALGKLCTAEPRFTAQLRD-----LHGIEILNSTMKHINDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MAEDQEKDLQKFLKNVDEIT---------------------------
----NLIQGMNSDDPAAQQKAVLETERRLLLTEKDQ----DEDSCRTALDKTLINPPK--
----STDEINSEAFLASLEKDAKERAKRRRENKVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKEKGNEAFAKGDYETAVLRYS
EGLEKLND

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 291)

KVLY-NRAQAYIKLGDYQKALVDCDWAL------KC--DCTKAYFHMGXXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXX-----XXXXXXX
XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXENQRLLVVCPDMGRLLP
SLVASS-MTIRQQVLVLLL-QLAXXXXXXXXXXXXXXXXXLLEALVSFLDFSDK-SANTA
MGLLTDLALEE--XXXXXXXXXXX-XXXXXXXX-XXXXXXXX--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXARCEED---VDLFREVIYTLLGLMMNLCLQSPLVSE
VWAMEVSRRCMSLLNSQDGGLLTRAAGVLSRTLPSSL-KIMEEALRGGVVKKMIKFLKTG
GQTASHYAIKTLAVCTNSVHQAREEVISLDKXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPAESNNL-----
------LCF------------------GGRPAAPGDFLAGSRRWEEMFYTL--GFSICPV
ELRPLS-----------------------------------

------------------------------------------------------------
-------------MDADREKDLQKFLKNVDEIS---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDECRTTLNKTMISPPQTA
--MKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKG---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTAGNDAVEEMVCVSVLKLWQAVCS-GNEENQRVLVMHHDRARLLA
ALLSSEVLAIRQQSFALLL-QLAQTESGRSLIINHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCITVMGNL
SAEPTTRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLKLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAESSH-----LQFGGESA-APEALSPRRWEEMFHML--VFSLSSV
DPP---------PPLPQTCYP--------------------

MCHPFYFHNPALHLHSHAHPARAASGASPRQRCRGFESGPGGSRCPLAVPRCPPVSPGVP
SLSPRCP--PAMLRDEDTEADFQRFLRRVDDVT---------------------------
----NLLQGLSSPDSAVREKAIAETEKKLQEQGGSREEEE--EESRTTLNRTLINTSGS-
---ARAEAVDADGFLAALEKDAKERAQRRRRNEQLANALKEQGNEAFRAGDFALAIQRYS
QGLEKLRDKQE

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAYLKLHEYEKAISDCEWAL------KCNKN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CL

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFLMGKAH
LALQRFPE--CRQCYEKMLQIDPQKENLFKD---CVNEARLEEKRVRDEERAEREAQAGS
VAASSIQELLQRISSPGQDILYYTGGIRLLAEAVHSCTGQ--TFFRTN------NGFSIL
RN-----ETVRGAFCAESKSPAEVELCVSLLLLFQAACA-GNEENQRLLLAQPEVSAQLA
ELLSSGTAQLQRETLALIS-LYSEHETGRRLLLR-QDLSRWLQILMAFVKSTDA-RADSA
MNILSDLIGEE--RFQTQCRAMFSTGVLPLFTQLLV--CARQ--VNQAALARAVGVLGSL
CADVGLRAQLARSRECWQACLQLLDGCPDA--SSPGYQLCVFAVLGLMMNLLLESNGTIQ
DLAVPISGRCLALLSHQDGRIVTRSIGVLSRVLPASP-SAVEEVVRAGVVKKMLKFLKAG
GQLTCSYAIKTLSICTKSSRRAQEELLKWDKRLQVLLKLLEAGDELLVGNAAF-CLSQCL
LL--PGAASALLGSSVVQ---------------LLLRQAGGDAHR--------TSVQQNS
AIALGRLCVAEPRHIQQLRK-----LNGLAILNSSMKYLPSS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKDKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------DGFSII
SD----NEVIRRCFSTAGKDAIEETVCVSVLKLWQAVCC-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPAVTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEEN---VALFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAVCPQRWEEMFHML--VFSLPRV
DPP---------PPLPQPCYR--------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPETA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------NGFSII
SD----NEVIRRCFSTAGKDAVEETVCVSVLKLWQAVCC-RNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLIRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAIKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAGSPHRWEEMFHML--VFSLSSV
DPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MADDHEKDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVQQRAVLETEKRLLFTEEVQ----EEDGCRTTLNKTMISPPQAS
--PENTDEINSEAFLASVELDAKERARRRRENKVLADALKQKGNEAFARGDYEAAILCYS
EGLEKLRDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDFQKAVVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYNV--SRECYQKILEINPQLQTQVKE---YLNQVNLREKADLQEKEAHELLDSGK
NTAVTVKNVLETLCKPDQTPLFYAGGIEILTEMIKDCPEQ--TLFRTH------NGFSVI
GE----NEVIRRCFSTAGKDAMEETVCVSVLRLWQAVCA-GNEENQRLLLLRPEMGGLLP
SLLTSRVLGLRKQSLALLL-QLARTDHGRSLVVGHLDLTRLLEALVSFLDFSDK-KANSA
MELLTDLALEE--RFQVWFQANLP-GVLPALTG-VLRREPTI--TNTSALCQCIALVGNL
SAEAAVRRQMCASEEFGDACLGLMARCEEA---VDLFRDVLYTLLGLVMNLCLQSPFICE
VWAVEVSRRCMFLLNSQDGGILTRAAGVLSRTLSSSR-KIIEEALRAGVVKKMIKFLKTG
GQTASRYAVKILAICTNSQHEAREEVIRLDQKFGILLKLLSSEDEIVVANAAL-CLGNCM
EV--PRAASSLLQTDIVQ---------------VLLRHAGGDAQK--------TAVQLNA
GIALGKLCTAEPRLQKKLMV-----LIHQDT---ARGYRPPPTP----------------
----ATFSECPGKGVTADNRL------QQEVSRGPAVAWHL

------------------------------------------------------------
-------------MADEQEKDLEKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVQEKAIFKTEKRLLVTEEDQ----DEDGCRTTLNKTTISPPQAP
--GKNADEMNAEAFLASVEKDAKERAKRRKENRAL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKGKGNEAFVRGDYETAILCYS
EGLEKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYMKLGDYQKALVDCDWAL------KCDEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAH
LALKNYSV--SRECFQKILEINPQLQTQVKD---YVDQVDLREKADLQEKEAQQLLDSGK
STAVTTRHLLGTLSKPDQNPLFYTGGIEILTELMEDCTER--TLFRTH------NGFSII
SE----NEVIRRCFSMAGKDAVAETLCVSVLRLWQAVCR-GNEENERQLVAHPGSGRLLP
SLLASGVLPIRQQSLALLL-QLAQTKTGRSLVISHLDLTRLLEALVSFLDFSDE-RATSA
MGLLTDLALEE--RFQVWFRANLA-GVLPALRA-VLKRDPKE--VNTSALSQCVAIMGNL
STDAATRRQMSASEEFGDACLGLMARCEED---VDLSRDVIYALLGLMMNLCLQSPFVSE
VWAAEVSRRCMLLLNSQDGGILTRAAGVLSRTLPSSV-EIVAEALRAGVVKKMIKFLKAG
GQTASRYAVKTLAICTNSCHEAREEVIRLDKNFSVLMTLLGSEDEILVGNAAL-CLGNCM
EV--PQVASSLLKTDIVQ---------------VLLKLAARDVGE--------RAVSLNA
GIALGKLCTAEPRFAAQLRE-----LHGLEILNSTVKHIQDS------------------
-----------------------------------------

------------------------------------------------------------
------------MSNPQEEQDLQKFLRDVDEVT---------------------------
----NLIQGLNSADPSIQVKAIAETEKRLSSTKPKD-----GSKKKPQVDRTVVNTRAPD
-LPNHEEMMNRDGFMAALEKDAEERARRRKENEAFANALKDKGNDAFSKGDYEAAIEKYT
EGLKKQKDMPM

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLQKYDQAIEDCDWAL------RCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCI

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KALFHMGKAY
LAQEQYRK--SRECFLKILEIDPQKEKLCKG---CIDEVDAEEKRQREEQSAKEAFESGK
SAAVSVSQLLEKLSAPDKTPLYYAGGMRLLTEAVQDGTEQ--TLFRTN------NGFSVI
ND----NEVIRRSFRKRITERDWQHISTAVLKTAEVVRSVGNEASGVYILKHGQTSALPA
SVLDFNSHNSWPQA----L---FFPHSATAAVVDHNGLVLWLQLFLSFLKLSDN-RARYA
MNLLTSLIAED--KFKIQCRIKLSTEALPLFTQLLTVLDPQISQVQSSLLCRCLILVVSR
NKVPSSQVNPCGC--------VFEDECWVE-GKITRYPKCLHAVLGLMMNLSLQHSLVIQ
EFAEEITQKCMSLVNSKEGRIVTRAIGLLSHILPVSL-VALEEAMKQGVVKKMIKFLKTG
EEATSGYALKTLAACVRNSRQAQEQIVKSDKKCSTFLKLLRSQNDVVVGNAAF-CLGKCL
EV--PGMATNLLDTNVVK---------------ILLKVAGREAEK--------TQAQENA
AIALGKLCNADARHTSRLRE-----LNGMAVLNAVMKHVQH-------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDHEKDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPLVQQKAILETEKRLLFTEEVQ----EEDGCRTTLNKTMISPLQAP
--LENADGISSEAFLASMELDARERARRRRENKVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 243)

ADALKEKGNEAFARGDYEAAIVCYS
KG

ENSGT00730000110724_0_Linker_0_1 (243, 252)

LDKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYLKLGDYQKAVVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--ARECYQKISEINPQLQAQVKD---YLNQVNLREKADLQEKEAHRLLDAGK
NTAVTVRNLLETLCKPDQTPLFYAGGIEILTEMMKDCTEQ--TLFRTH------NGFRLI
SE----NAVLRRCFSTAEKDAAEEMVCVCVLRLWQAVCT-GNEENQRLLLESPDLGRLLP
SLLAARALTVRQQSLALLL-QLTQTDHGRGLIISHLDLTRFLEALVSFLDFSDK-EANSA
MGLLTDLALEE--RFQVWFQANLP-GALLVLTG-VLKRDPMI--TNPSALRCCIALMGNL
SAEAAIRRQMSASEEFREACLGLMVQCEED---VDLFREILYTLLGLVMNLCLQSPILYE
VWASEVSKRCIFLLNSQDGGILTRAAGVLSRTLSSSR-KIVEEALRAGVVKKMIKFLKTG
GQTASRYAIKTLAVCTNSSHEAREEVMRLDKKFGILMTLLRSEDEVVVGNAAL-CLGNCM
EV--PGAAPSLLKTDVVQ---------------VLLRHAGGDAQK--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGLEILSSTMKYIAH-------------------
-----------------------------------------

------------------------------------------------------------
----MEG--FWSTMADNQDKDLQRFLKNVDEVA---------------------------
----NLIQEMNSDDPAVQQKAVLETEKRLLLMEGAR-E--EEDGCRTTLNKTTISPPQAP
--TENTEEINPEAFLASVEKDAKERARRRRENKALADALKEKGNEAFGRGDYNTAVLHYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAYIKLGDYQKALEDCDWAL------KCDENYTKAYFHMGKAH
LALRNYGA--SRDSYRKILEINPKLQTQVKE---YLNQVDLREKADLQEQEARGLLDAGR
STAVSTRNLLETLSKPGRTPLFYAGGIEILTEMMQDCTER--TLFRTH------NGFSII
SD----NEVLRRCFSTAEKDAVEETACLSVLKLWQAVCS-GNEENQRLLVSHPDRAALLP
SLLASRVLAIRQQSLALLL-QLAQTENGRNLIASHLDLARLLEALVSFLDFSDK-KATSA
MQLLTDLAIEQ--RLQVWFQANLP-AVLPALTG-ILKHDPRT--TNYTAFCQCLAILGNL
SAEPATRRHMAACEEFGDACLGLLARCEED---AAGFREVTYTLLGLLMNLCLQTPFVSE
VWAAELSAQCLSLLNSQDGGILTRAAGVLSRTLPSSP-RITQEALRAGVVKKMMKFLKTG
GQTASRYAIKILAACTNSCHGAREEVVRLDKQFGVLLQLLGSEDEVLVGNAAL-CLGNCM
EV--PHVAASLLKTDLVQ---------------VLLKLAGGDAQK--------TAVQLNA
GIALGKLCTAEPRFATQLRE-----LHGIEILSSTMKYITDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----TLIQELNSDDPVIQQKAVHQTEKRLMLMEEA--Q--EEDECRTTLNKTMISPPQAA
----NADELKPEAFLASVEKDAKERAKRRRENKVLADALKEQGNKAFAKGDYETAILHYN
EGLDKMKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYQKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSM--SRQCYQKISEINSKLQTQVKE---YLHQVDLQEKADFQEKEAHELLDLGK
NTAVTTKNLLETLSKPDQTPLFYAGGMEILTDVMKDCTEQ--TLFRTH------NGFSII
SD----NEVIRRCLSIAEKDMIEETVCVTVLKLWQAVCS-ENEENQRLLVLHPNIVRLLP
SLLTSKVMAIQQQSLALLL-QVTQTEHGRSLVISHLDMTRLLEALLSFLDFSDK-KASTA
IGLLTDLALEE--RFQVWFQANLP-DALFAFTG-VLKRDPMV--TNSSALCRCIAIMGNL
SAEPATRRHMLACDEFRDACLGLLARCKDD---MDLYREVTYTLLGLMMNLCLQVPFVSE
VWAVELSRRCLSLLNSQDGGILTRAAGVLSRTLSSSQ-KIIKEAVRAGVVKKMIKFLKTG
GQTASHYAIKILAVCTNSYCEAREEVIRLDKKFSVLLKLLTSEDEILMGNAAL-CLGNCM
EV--PNVASSLLKTDVVQ---------------VLLKLAGGDSRE--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGLEILSSTMKYINNS------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MGNEAFAKGNYEMAIQHYS
KGLEKLKDMQV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYLKLREYPKALLDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 290)

KC

PF07719 // ENSGT00730000110724_0_Domain_2 (290, 324)

PKAHFLMAKAH
LALGDYNK--SRQCYRKMLESNPSLEKQVAG---YLEHVALQEKAAMQEQEAQEELASRK
STAVATKTLLQTLTQPDQLPFFYAGGTEALAELMRDCTEQ--TLFRTN------NGFSII
ND----NKVIKRCLSTVGDSGPEEAVCLSVTKLWHAVCR-GNEVNQHRLVTHPGLGALLP
SLLLGRGRPVQQQILALLT-LLAETETGRNLLLSHMDLPSLLQALVTFVNSSDV-RAGEA
MRLLTDLALED--RFKAWFRNHLS-TALPILVG-TL-RNPAL--ANQATLSQCLAIVGNL
SADVTIRSQLAACPDLWDVCLEFLLGWEED---LVPVRGTVYAALGLLMNLLLEPTRVPK
GRAAVVNQRCLALLGCEDGGILTRAAGALSRSLAASPPDAMEEVVAGGVVKKMIQFLKAG
GQTAPRYAMKTLAICTKSSLRAREEVVRLDKRFGVLSRLLDSEDGVVVGNAAL-CLGACV
EV--AGVAASLLHSDIVD---------------LLLRHVANAGP---------ATVSHNA
AIALGKLCTAEPRHVVRLRE-----LHGVEILHGAMKHVSGS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQEKDLQRFLENVDEIT---------------------------
----NLIQEMNSDDPIIQQKAVLETEKKLLLMERE--Q--DEDRCRTTLNKTIISPPRAP
---ENAGEMNPEAFLASVEKDAKERAKRRRESRVLADALKEKGNEAFAKGDYETAILCYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYEKALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LAMKNYSK--SRECYQKMGEINPKLQTQVKE---YLNQVTLQEKADLQEKEARESLHSGK
NTAMTTKNLLETLSKPGQTPLFYAGGIEILTEMMTNCTER--TLFRTY------GGFSTI
SD----HKLIRRCLFSAGKDAAEEVLCVAVLKLWQAVCS-DNEENQRRLVTHPDMASLLP
SFMTSRILIIQQQSLALLL-QLTQTENGRNQVIKHLDLIRLCEALLSFLDFSDK-KANTA
IGLLTDLTLEE--RFQVWLQANLP-GVLPALTG-VLKREPKL--TSPSALCQCIALMGNI
SAEPTARGHMMACEEFGDACLELLVKCEED---MDLFREVTYTLLGLIMNLCLEVPFLSE
MWASEMSRKCLSLLNSQDGGILTRAAGVLSRTLSSSL-TIMEEALTAGVVKKMIKFLRTG
GQTASRYAIKTLAICTNSCHPAREEVMRLDKKFNILISLLDSEDEIVVGNAAL-CLGNCM
EV--PSAASSLLKTDIVQ---------------VLLKLAGSDSQR--------TAVQLNA
GIALGKLCTAEPRFVGQLRE-----LHGIEILNSTMKYMKDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPQTV
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------NGFSII
SD----NEVIRRCFSTAGKDAIEETVCVSVLKLWQAVCC-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEEN---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDKKLSMMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAVSPHRREEMFHVL--VFSLPRV
DPP---------PPLPQPCYP--------------------

------------------------------------------------------------
------------MLHGQQEEDFQRFLRRVDDIT---------------------------
----NLLQDLNSPDPAVKENAIAETEKRLREQEAGKE-----EESKTTVNRTVINTRASD
--VSTAEAVNPDGFLAALEKDAKERAKRRKRNERL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ANALKEKGNDAFRKGDYDTAIQRYT
EGLEKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

K

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

QELYTNRAQAYLKTHEYEKAIGDCEWAL------KCSEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF07719 // ENSGT00730000110724_0_Domain_2 (290, 325)

IKAYFLMGKAH
LALKHYSE--SRQCYQKMLEIDPQKESLFKDCQDCINEVNLEEKRMKEEDRAMKEFLSGK
LAALSVKELLQKLDRPDQNILFYAGGIKALTGAVKDCTEQ--TLFRTN------NGFSII
N----DNEVVRRGFCAERKHIAEVDLSVSLLLLWQAVCA-GNEENQRLLLTHPDVNAQLS
KLLASGVLEIQKETLALIM-LYSENENGRRLLVRHQDLSRWLQILVMFVKNTDA-RATSA
MNILSDLTQEE--KFKTQCRIMFSTGVLPVFTQLLEETSAKM--VNQAALAQCIGIMGNL
CADTVIRMQMADCKECWQACIKLVDEYFDV--NTPKYQECLFAVLGLMMNLLLESNAIIQ
CLAVDISGRCMSLLGDKDGRIVTRAIGVLSRVLPASS-LAVEAVVKEGVVKKMIKFLKAG
GQITSNYAIKTLSICTRSNRQAQEEVVKSDKRFSVLLKLLDSENEIIVGNAAF-CLGQCL
VV--PGAATSLLNSNVVM---------------TLLKHAGGDATR--------TSVQENA
AIALGKLCVAEPRHIVQLRE-----LNGMAILNSSMKYVHSI------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----TLIQEMNSDDPVIQQRAVQQTEERLMLMEEA--G--EEDGCRTALNKTTISPPQAA
--AQNTNEINPEAFLASLEKDAKERAKRRRENKVLADALKEKGNKAFAKGDYAAAILSYS
EGLDKMKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGEYQKALADCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKKYSV--SRQCYQKMSEINPKLQTQVKE---YLHQVDLQEKADLQEKKARELLDSKN
STAVTTKNLLETLSKPGQAPLFYAGGIEILTDLMKDDAEQ--TLFRMH------NGFSSI
SD----NEVIRRCLSAAEKDVIEETVCVTILKLWQAVCR-GNEENQRLLVLHPDTARLVP
SLLTSKVMAIQQQSLALLL-QLSQTEHGRSLVISHLDLTRFLEALLSFLDFSDK-KASTA
IRLLTDLALEE--RFQVWFQANLP-GVLPILTG-VLKRDPMV--TDSSALSRCIAIMGNL
SADAASRRHMAACEEFGDACLSLLAKCEDD---RDLYREITYTLLGLVMNLCLQVPFSSE
VWAMELSRRCLSLLNSQDGGILTRAAGVLSRTLSCSQ-KTIKEAVRAGVVRKMIKFLKTG
GQTASHYAIKILAICTNTCCDAREEIVRLDKKFSVLLNLLSSEDEILMGNAAL-CLGNCM
EV--PSIASSMLKTDLVQ---------------VLLKLAGGDSQR--------TAVQLNA
GIALGKLCTAEPRFTAQLRE-----LHGLEILNSTMKYLNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EVDGCRTTLNKTMISPPQAP
--TKNVEEINSEAFLASVEKDAKERAERRRENKVLADALKEKGNEEFVKGDYEAAIRCYT
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALADCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 323)

KAYFHMGKAH
LALKNYSM--SRECYKKILEITPSLQAQVKD---YLNQVDLQEKADLQEKEAWAMIDSGK
NTAVTTKNLLESLSKPDQIPLFYAGGIEILTEMMKDCTER--TLFRIY------NGFSTI
SD----NEVIRRCFSMVVKDAVEETVCVSVLKLWHAVCD-GNEENQRVLVTHPDRARLLP
ALLACRVPAIEQQSLALLL-QLAQTEDGRSLIIGHLDLTGLLGALLSFLDFSDK-RANTA
MALLTDLALEK--RFQAWFQASLP-DILPELTG-VLKRDPKV--TNLSALCQCVAVMGNL
SPEPATRAAMSACEDFGDACLDLLARCEED---MDLFREVIYSLLGLMMNLCLQAPFFSE
DWALVASRRCMFLLHSRDGGLLTRAAGVLSRTLSSSL-RIIEEAQAAGVVKKMIKFLKTG
GQTASRYAIKILAVCTNSYHEARAEVIRLDKNFSILRKLLYSADEVLVGNAAL-CLGNCM
EV--PRVASSLLKTDIVQ---------------VLLKLSGGDSKN--------TAVQLNA
GIALGKLCTAEPRFTDQLRELH-----GL-------EILN----STT--------KYLSD
S----------------------------------------

------------------------------------------------------------
-------------MADNQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPAVREKAVLETEKRLLFTGEDQ----EEDECRTTLNKTMISPPKAP
--TKSADEINSEAFLASMEKDAKERAKRRRENKVLADALKEKGNEAFVRGDYETAILLYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYQRALVDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF00515 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--ARECYQKILEINPQLQTQVKD---YLNQVDLREKADLQEKEAHELLDSGR
STAETTKNLLETLSKPDQMPLFYAGGVEILTEMMKDCTER--TLFRTH------NGFSII
SE----NEVIRRCFSTAGKDAVEETVCVSVLRLWQAVCA-GNEENQRLLVVHPGTGGLLP
SLLASSVLTIRQQSLALLL-QLAETENGRSLIISHLDLTRLLEALLSFLDFSDK-KADSA
MRLLTDLALEE--RFQVWFEANLP-GVLLALTG-VLKRDPKV--TNTSALCQCIALMGNL
SAEAAIRRQMSASEEFGDACLGLMARCEED---VDLFREVMYTLLGLVMNLCLQSPFVSE
VWAMEVSRRCMSLLNSQDGGILTRAAGVLSRTLSSSL-KIIEEALRAGVVKKMMKFLKTG
GQTASRYAVKTLAVCTNSNHEAREEVIRLDKKFGVLMKLLSSEDEILVGNAAL-CLGNCM
EV--PHVASSLLKTDIVQ---------------VLLKHAGGDAQK--------TAVQLNA
GIALGKLCTAEPRFAAQLRE-----LHGIEILSSTMKHISGS------------------
-----------------------------------------

------------------------------------------------------------
------------MAKEEEERDLQKFLKNVDEIS---------------------------
----NLIQDLSSDDIAVRDRAMTEAENRLQVPKDQ-----EEEECRTILNKTVISPPQAP
--TKNVDDTNQDGFMEVLEKDARERAQRRKENKSLANALKEKGNEAFLKGDYRTAVQLYS
QGLKKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAYIKLEEYEQALVDCEWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYRM--ARQCYQKILEINPKLQSQVKD---SLNKVDQKEKVELQEKIALEELESGK
ESAVTTKNLLKSLSKPDQTALFYAGGLQLLTELMKDCTEQ--TLFRTH------NGFCII
ND----NKIIKRCFVAEGKNGVEEALCVSVLKLWQAICD-GNEENQRLLLTNSDMDLLLP
FLLISKVVSIQQQSLRLLL-LLCQTQNGRVLVLNHMDLTRLLQVFVAFVNSSEEKDAQTV
TQLLNGLALEE--RFKTRLQSNLS-ALLTLISM-L--KNPEN--AYPSILCQCVAIMGNL
STDATIRKQMSDCGECWDACLDLMVKCEKN---VTQFRETLYATLGLMMNLSLEFLSITE
ILAEEVSRRCVSLLSCEDGGILTRAAGVLSRVLSASS-KAIEETVKADVMKTMIRFLKAG
GQTASRYAIKIIAVCTNSCYEAREEVARLDKKFSILIKLLDSEDEIIVGNAAL-CIGNCA
EV--PGIAFILLKSDIVK---------------ILLKLAGGDSKE--------TSVQLNA
GIALGKLCTAEPRHTVQLEE-----LHGIEILNSTMKYIKKT------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----SLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKDKGNEAFAEGNYETAILHYS
EGLEKLKDVKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLKNYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------DGFSII
SD----NEVIRRCFSTAGKDAIEETVCVSVLKLWKAVCC-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPAVTS-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEEN---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFEGESAA-PEAVSPHRWEEMFHML--VFSLPRV
DPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MADDQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSKDPIIQQKAIQETEKRLRFAEEVPE----EXXXXXXXXXXXXXXXXXX
--XXNTDDMSPEGFLASIEKDAKFRAKRRQENKVL

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKEKGNEAFVKGDYKAAILCYS
EGLEKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

RVLYTNRAQAYIKLGDYEKAVTDCDWAL------KCDEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAH
MALKNYSQ--SRECFQKILEISPDLQREVKD---CLRQVDLQEKADVQEQEAQELLASGR
STAVSTKALLETLSKPGQMPLFYAGGIEILTELMEDSAER--TLFRTH------KGFSII
RE----NATVRXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXLLEALASFLDISDK-RASSA
MGLLTDLAQEE--RFQVWFRQRA--DILP-L-T-GLRRDPTA--TSPSALYQCVAVMANL
SMDVASRREMAASEELGDACLELLTRCEED---MEAFRDVIYTLLGLLMNLCLHTPFVSE
VWATEVSRRCFSLLNSKDGGILTXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXAG
GQTASRYAIKTLVICTNSAHEAREEVLRLDKKLSLITELLHSEDEILAGNAAL-CLGNCM
EV--PR-APGLLSSDIVR---------------VLLRLAGSDSQP--------SAVQLNA
GIALGKLCTAEP------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQNAVLETEKRLLLMEEDQ----EEDECRTTLNKTVISPPQTA
--VKSAEEVNSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILHYS
EGLEKLKDVKVLYTNRAQAYMKLKNYEKTLVDCEWAL------KCDEKCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKVN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDSGK
NTAVNTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRMH------DGFSII
GD----NEVIRRCFSTAGKDAIEETVCVSVLKLWQAVCR-GNEENQRVLVMHPDRARLLA
TLLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALTG-ILKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEEN---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALQAGVVKKMMKFLKTG
GETASRYAVKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLR-AGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAKSSH-----LQFGGESAA-PEAVSPHRWGEMFHVL--VFSLPRV
EPP---------PPLPQPCYP--------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPGVQQKAVLETEKRLLLMEEDQ----EEDGCRITLNKTLISPPQTT
--VKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAKGDYETAVLRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSA--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADRQEKEAHALLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEIIKECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTAGKDAAEETVCVSVLKLWQTVCS-GNEENQRVLVMDPDRARLLA
ALLSSRVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EAVTA
MGLFTDLALEE--RFQVWFQASLP-GVLPALAG-VLKRDPKV--SSSSALCQCIAIMGNL
SAEPATRRQMTACEEFGDGCLSLMARCEED---VDLFREVIYTLLGLLMNMCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMIKFLKTG
GKTASRYAIKILAICTNRCHEAREEVIRLDNKLSIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLVQ---------------VLLRLAGSDMQK--------TAVQVNA
GIALGKLCTAEPRVPAESSH-----LRFGGK-----CSLFSRRWEGMFHML--VFSLSSV
DPP--------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIS---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDECRTTLNKTMISPPQTA
--MKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILYYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADLQEKEAHELLDLGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMIKECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTAGKDAVEEMVCVSVLKLWQAACS-ENEENQRVLVMHHDRARLLD
ALLSSKVLAIRQQSLALLL-QLAQTESGRSLIISHLDLTRLLEALVSFLDFSDK-EANTA
MGLFTDLALEE--RFQVWFQANLP-GVLPALIG-VLKTDPKV--SSSSALCQCIAIMGNL
SAEPATRRHMAACEEFGDGCLSLLARCEED---VDLFREVIYTLLGLMMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSL-KIVEEALRAGVVKKMMKFLKTG
GETASRFAIKILAICTNSYHEAREEVIRLDKKLSIMMKLLSSEDEILVGNAAL-CLGNCM
EV--PNVASSLLKTDLLQ---------------VLLKLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRVPAESSH-----LQFGGESA-VPEALSPRRWEEMFHML--VFSLPSV
DPP---------PPLPQTCYP--------------------

------------------------------------------------------------
-------------MADDEEKDFQKFLKNVDEIT---------------------------
----TLIQEMNSDDPVIQQKAVHQTEKRLMLMEEA--Q--EEDECRTTLNKTVISPPQAA
----SADEINPEAFLASLEKDAKERAKRRQENKVLADALKEEGNKAFARGDYETAILNYS
EGLDKMKDMTVLYTNRAQALIKLGEYQKALVDCDWAL------KCDEKCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSV--SRQCYQKISEINPKLQTQVKE---YVHQVDLREKADLQEKEAHELLDSGK
NTAVTTKNLLETLSKPDQTPLFYAGGMEILTDVMKDCTEQ--TLFRTH------NGFSII
SD----NETIRRCLSAAEKDVIEETVCVTVLKLWQAVCS-ENEENQRLLVLHPDVARLVP
SLLASKLMAVQQQSLTLLL-QLTQTERGRSLVISHLDMPRLLEALLSFLDFSDK-KASTA
IGLLTDLALEE--RFQVWFQANLS-GILPVLTG-VLKRDPMV--TNPSALCKCIAIMGNL
SAQADARRHMSACEEFGDACLGLLAKCEDD---VDLYREVIYTLLGFMMNLCLQVPFASE
FWAEELSRRCLSLLNSQDGGILTRAAGVLSRTLCCSQ-KIIKEAVRAGVVKKMIKFLKTG
GQTASHYAIKILAICTNSCCEAREEVVRLDKKFSVLLKLLSSEDEILMGNAAL-CLGNCM
EV--PSVASSLLNTDVVQ---------------VLLKLAGGDSQK--------TAVQLNA
GIALGKLCTAEPRYTVASTE-----TGRGQGPDSAFKRMPTVT-----------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----NLIQEMNSDDPFIQQKAVLDTEKKLLLMERE--Q--EEDGCRTTLNKTMISPPQAP
---ENANEMNPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVKGDYETAIFFYS
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 289)

LYTNRAQAYIKLGDYQKALVDCDWAL------KCDEN

ENSGT00730000110724_0_Linker_1_2 (289, 291)

CT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKNYSK--SKECYQKIGEINPKLKAQVKE---HLNQVTLREKADLQEKKARESLDSGK
NTAMTTRNLLETLSKPGQTPLFYAGGIEILTEMMTDCTER--TLFRTY------GGFSII
ND----HEVIKRCLFLAGKDAVEEIVCVSVLKLWQEVCI-DNEENQRLLLSHPDMAKLLP
SFMDSRILVIQQQSLALLL-QLTQTDNGRNQVIKHLDMTRLCEALLSFLDFSDK-KANTA
IGLFTDLALEE--RFQVWFHANLP-DVLPALTG-ALKREPKL--TSPSALCQCIALMGNI
SAEPTARRHMLAYEEFGDACLDLLVKCEED---MDLYREVTYTLLGLIMNLCLEVPFLSE
SWAMKISRKCLSLLNSQDGGILTRAAGVLSRTLSSSQ-TIVEEALTAGVVKKMIKFLKTG
GPTASRYAMKTLAVCTNSYHAAREEVMRLDKKFNVLMTLLASEDEVVVGNAAL-CLGNCM
EV--PSAASSLLKTDIMR---------------VLLKLAGGDSQE--------TAVQLNA
GIALGKLCTAEPRFAVQLQE-----LHGIQILNSTMKHLNDS------------------
-----------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----NLIQGMNSDDPDVRQKAVQETEKRLLLQEKD--Q--DEDECRTTLNKTMISPLEAS
--SKDAEEMDSETFLVSLEKDAKERARRRQENKVF

PF00515 // ENSGT00730000110724_0_Domain_0 (216, 249)

ADALKEKGNEAFAKGDYETAVVCYS
EGLKKLKD

ENSGT00730000110724_0_Linker_0_1 (249, 250)

M

PF00515 // ENSGT00730000110724_0_Domain_1 (250, 289)

KVLYTNRAQAYIKLGDYEKALVDCDWAL------KCDEK

ENSGT00730000110724_0_Linker_1_2 (289, 290)

C

PF00515 // ENSGT00730000110724_0_Domain_2 (290, 325)

TKAYFHMGKAN
LALKNYSV--SRECYQKILEIDPKLQTQVKD---CLNQVDLQEKAELQEKKAHELLDLGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMMTECTER--TLFRTH------NGFSII
GD----NEVIRRCFSAVGKDAVEETVCVSVLRLWQAVCS-GNEENQRLLVTYPNMAELLP
SLLDCRVMTIQQQSLVLLL-QIAQTENGRSLILSHLDLTRXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXX--XFQVWFQAKLP-GVLPTFIG-VLKRDPKT--TNPSALCQCIAIMGNL
SAEAATRRQMAGSEEFRNACLGFMAKCAEG---AAPLREVLYALLGLLMNVCLHSPFASE
AWAMEVSRRCMVLLNSQDGGILTXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPAESGHLPHFGG
GFAASKSRWAEMVYILV--------FSASEELPSLFCYI---------------------
-----------------------------------------

------------------------------------------------------------
-------------MADDQEKDLRKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLQLMEEDQ----EVDECWTTLNKTVISPPQAP
--MKNAEEMDSEAFLTSVEKDAKERAKRRRENQVLADALKEEGNEAFVKGDYATAVLRYT
EGLQKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLEDYERALEDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 323)

KAYFHMGKAH
LALKNYSM--SRECYKKILEINPMLQTQVKD---YLNQVDIRERADLQEKEAHEMLESGE
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTELMKDCTEQ--TLFRTH------NGFSTI
SD----NEVIRRCFSTAGKDAIEETVCVSVLKLWQAVCR-ENEENQRVLVMHPDTGGLLP
SLLASGVPAIQHQSLALLL-QLAETENGRSLILSHLDLTRLLEALVSFLDFSDK-KANTA
MALLTDLALEK--RFQVWFQASLP-GVLPALIG-VLKRDPRV--TSSSALCQCIAIMGNL
SAEPATRAHMAACEDFGDACLGLMARCEED---VDLFREVIYTLLGLLMNLCLQAPFFSE
DWAAEVSRRCISLLNGQDGGILTRAAGVLSRTLSSSL-KIIEEAQRAGVVKKMIKFLKTG
GQTASRYAIKTLAVCTNSYHEAREEVMRLDKKFSILMKLLHSDDEILVGNAAL-CLGNCM
EV--PNAASSLLKTDLVQ---------------VLLKLSGGDAKN--------TAVQLNA
GITLGKLCTAEPRYAASFLPS------LSPL---PLPLPP----SPLLPPL--FFLYFSK
NRPPLDFIFLPGPKQMKGCPVRATCPCQREQ-SGEAE----

------------------------------------------------------------
------------------------------------------------------------
----TLIQEMNSDDPVIQQRAVQQTEERLMLMEEA--G--EEDGCRTALNKTTISPPQ--
----NTNEINPEAFLASLEKDAKERAKRRRENKVLADALKEKGNKAFAKGDYATAILSYS
EGLDKMKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGEYQKALADCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LALKKYSV--SRQCYQKMSEINPKLQTQVKE---YLHQVDLQEKADLQEKKARELLDSKN
STAVTTKNLLETLSKPGQAPLFYAGGIEILIDLMKD--EQ--TLFRMH------NGFSII
SD----NEVIRRCLSAAEKDVIEETVCVTVLKLWQAVCR-GNEENQRLLVLHPDTARLVP
SLLTSKVMAIQQQSLALLL-QLSQTEHGRSLVVSHLDLTRMFLPT---------------
---------SW--VVILWFQANLP-G----------KRDPMV--TDSSALSRCIAIMGNL
SADAAARRHMAACEEFGDACLSLLAKCEDD---RDLYREITYTLLGLVMNLCLQVPFSSE
VWAVELSRRCLSLLNSQDG-----AAGVLSRTLSCSQ-KTIKEAVRAGVVRKMIKFLKTG
GQTASHYAIKILAICTNTCCDAREEIVRLDKKFSVLLNLLSSEDEILMGNAAL-CLGNCM
EV--PSIASSMLKTDLVQ---------------VLLKLAGGDSQR--------TAVQLNA
GIALGKLCTAEPRFTAQLRE-----LHGLEILNSTMKYLNDS------------------
-----------------------------------------

------------------------------------------------------------
-------------MDADQEKDLQKFLKNVDEIT---------------------------
----NLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQ----EEDDCRTTLNKTVISPPQTT
--MKSAEETDSEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAKGDYETAILRYS
EGLEKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYMKLEDYEKALVDCEWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF13181 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAN
LALKNYSV--SRECYKKILEINPKLQTQVKD---YLNQVDLQEKADHQEKEAHKLLDSGK
NTAVTTKNLLETLSKPDQIPLFYAGGIEILTEIIKECTEQ--TLFRTH------NGFSII
SD----NEVIRRCFSTAGKDAAEETVCVSVLKLWQTVCS-GNEENQRVLVMDPDRARLLA
ALLSSRVLAIRQQSLALLL-QLAQTESGQSLIISHLDLTRLLEALVSFLDFSDK-EADTA
MGLFTDLALEA--RFQVWFQANLP-GVLPALTG-VLKRDPKV--GSSSALCQCIAIMGNL
SAEPATRRHMTACEEFGDGCLSLMARCEED---VDLFREVIYTLLGLLMNLCLQAPFVSE
VWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLASSL-KVVEEALRAGVVKKMIKFLKAG
GETASRYAVKILAICTNSYHEAREEVLRLDNKLGIMMKLLSSEDEVLVGNAAL-CLGNCM
EV--PNVASSLLKTDLVQ---------------VLLRLAGSDTQK--------TAVQVNA
GIALGKLCTAEPRAVISDLE------EGAAP-----EALSSRRWEEMFHML--VFSLSSV
DPP---------ATAPTLFP---------------------

------------------------------------------------------------
-------------MADDQERDLQRFLENVDEIT---------------------------
----NLIQEMNSDDPVIQQKAVLETEKKLQLMERD--Q--EEDGCRTTLNKTMISPPRAP
---ENADEMNPEAFLASVEKDAKERAKRRRESRVLADALKERGNEAFVKGDYEAAILCYT
EGLGKLKDMKV

PF00515 // ENSGT00730000110724_0_Domain_1 (252, 288)

LYTNRAQAYIKLGDYEKALMDCDWAL------KCDE

ENSGT00730000110724_0_Linker_1_2 (288, 291)

KCT

PF07719 // ENSGT00730000110724_0_Domain_2 (291, 324)

KAYFHMGKAH
LAMKNYNK--SRECYQKIGEINPKLQTQVKE---YLNQVTLREKADLQEKEARESLDSGK
KTAMTTRNLLETLSKPDQTPLFYAGGIEILTEMMTDCTER--TLFRTC------GGFNTI
SD----HEVIRRCLFSAGKDAVEEVLCVAVLKLWQAVCS-DNEENQRLLVTHPDMATLLP
SFMTSRVLVMQQQSLALLL-QLTQTENGRNQVIKHLDLIRLCEALLSFLDFSDK-KANTA
IGLLTDLALEE--RFQVWFQANLP-GVLPALTG-VLKREPKL--TNLSALCQCIALMGNI
SAEPTARRHMIACEEFGDACLDLLVKCEEE---MDVFREVAYTLLGLTMNLCLEGPFLSQ
MWAVDMSQKCLSLLNSQDGGILTRAAGVLSRTLCSSL-AIMEEALAAGVVKKMIKFLQMG
GQTASRYAIKTLAICTNSCHPAREEVMRLDKKFKILISLLDSEDEILVGNAAL-CLGNCM
EV--PSAASSLLKTDIVQ---------------VLLKLAGSDSQR--------TGVQLNA
GIALGKLCTAEPRFAARLRE-----LHGLEILNSTMKYMNDS------------------
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