Query Results 

------------------------------------------------------------
--MPLPSHLLPALVLFL------AGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCG
YHGASPT----------------LGAPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHQGKEASTAALRSPTLREAASSCKLRLWYHAASG--
-----DVAELRVELTHGAETLTLWQSTGPW-GPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

NCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDENPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPQRPSWPRRDHSRNSAQGSFLVSVAKP----GTPAILSS
PEFQASGTSNCSLVFYQYLRGSEAGCLQLFLQTLGPSAPRAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVSEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWRRVSAQESQGSSAAA-------AGHFLSLQRAW
GQLGAEARVLTPLLGPSGPSCELYLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGIWKVDKVLLGARRRPFRLEFVGLVDLDGPDQQGAGVDNVTLRDCSPTVTTERDREISC
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNY

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSPGGQGLWRR
QANASG-HAAW--GPPADHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLRSP-GTLR--VYLEERRR---HQVLSLSAYGGLAWHLGSVDVQA
ERAWRVVFEAVAAGVAHSYVALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1343)

CDFESGLCGWSHLAWPGLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGGQPALGPIALDDVEYLAGQCCQQPAPSPGNTAV-P---GSVPAVVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNEDGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--MPLPGHLLPILVLFL------GGSPGWAWVPNHCRSPSQALCNFVCDCGDCSDEAQCG
YHGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFERDPCGWRDISTSGYSWLRDRAGAM-LE
GPGPRSDHTLGTDL--GWYMAVGTHRGKEAATAALRSPTLREAAPSCELRLWYHTASG--
-----DVAELRLELTHGAETLTLWQSTGPW-GPGWQELAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWGCGLPAPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKACVEPQQLCDGEDNCGDLSDEDPRT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGQHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGLWSRS-----------
----------EGWARNHSAGSPGHPAWPCRDHSRNSAQGSFLVSVAEP----GNPAALSS
PELQASGASSCSLVFYYYLHGSEAGCLQLFLQTLGSSTPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSEHCRPVLEVST--PQPLPP-
---GPWAPAPGP------LSPSSRLRDFCQQGHLACGD-LCVPPEQLCDFEQQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWRRLSAQESQGAGAAA-------TGHFLSLQRAW
GQLGAEARVLTPLLGPSGPSCELHLAYHLQSRPRGFLALLVVD--SGSRELAWQALSS-S
AGGWKVDKVLLGARHRPFRLEFVGLLDLDGPDQQAAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPMVTTTRDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDAHWRRVESRGPERDHTTGR---GYFMLLDPTDPPARGHSAHLLS
RPQVPAVPTECLSFWYHLHGPQIGTLRLAMRREGE-DTHLWSRSGTHGNRWHQAWATLSH
QPGSRAPYQLLFEGLRDGYHGTMALDDVAMRPGPCWAPDYCSFEDSDCGFSPGGQSLWRR
QANASG-HDAW--GPPADHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLLSP-GALQ--VHLEEGRR---HQVFSLSAHEGLAWRLGSVDVQA
EQAWRVVFEAVGAGVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGGYSW
DWGGGAAPS-RYLQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELRVLLRSAQGQLAVWGAGGHRRHQWLEAQVEVASVKEFQIVFEA
TLGGQPALGPIGLDDVEYLAGQHCQQPVPSPGDTAT-P---VSVPAVVGGALLLL-MFLV
-LLGLGGRRWLQKSG----SCPFQSN-----TEATAHGFHNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--MCLPSHLLSTWVLFM-VTLPAAQSLGKTQVPNHCRSPIKAVCNFVCDCGDCSDETQCG
FHGASTIP----------------STSFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CNFEQDSCGWQDISTSGYRWLRDRAGAV-LH
GPGPHSDHTHGTDL--GWYMAVGTHSGKEPSTATLRSPVMREAAPTCEMRLWYHIASR--
-----DVAELRLDLTHGVETLTLWQTSGPW-GPGWQELAVNTGRIQGDFKV---------
-------------------TFSATRNATHRGAVALDDVEFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPIPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

RCPLGHH
HCQNKACVEPHQLCDGEDNCGDRSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQL-----------
----------EGWTRNHSAGSMVSPAWPHRDHSLNSAYGFFLVSMAKP----GTTAVLYS
PEFKGSVSYNCTFTFYYYLHGSEASHFQLFLQAQGLNTPQAP-----VLLRSRHGELGTA
WVRDRVDIQSAHPFRI--LLAGETGP--GGVVGLDDLIMSSHCMLVPAMST--LQSSLS-
---GPVPLALYP------QTSIKLPQQTCEPGHLSCGD-LCVPPEQLCDFQKHCAEGEDE
HKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFESA-SAGGWEDISVGKLQWQWVEAQK-SKPA-------GDAPGHFLSLQKAW
GQLRSEARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVE--NGFRELLWQAPGG-S
SGSWTVEKIILGARHRPFQLEFVSLVDLDGPGQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CNPMVTTESDQELS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQ---GFFMFLDPTDPPARGQGALLLT
RPQVPVVLKECLSFWYRLYGPQIGTLCLAMRREGEEDILLWSRSGTHGNRWHQAWVTLHH
QPEASTKYQLLFEGLRNGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTH
QSNASG-LASW--GPWIDHTTGTAQ--------GHYMVVDTSPNVLPKGHVASLTSEVHQ
PLSQPACLTFWYHMSFPNP-GTLR--VHVEESTR---RQELSISAHGRSAWRLGSVNVQA
EQAWKVVFEAVAAGVEYSYMALDDISLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1344)

CDFESGLCGWSHLPWPSLGGYSW
DWSSGATPS-RYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATT--ASCL
RFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGYLRDQWLQVQIEVSNSEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCEQPSPSQGEVAA-P---VSVPVAVGGALLFF-MFLV
-LMGLGGWHWLQK-Q----HCPGQRS-----TDAAASGFDNILFNADHVTL-PESITSNP
QSPADLA-------------

------------------------------------------------------------
--LCLPSGGSSTH--PA-AVLPAGGSPG-QGVPSRCRSPSEAVCNFACDCLGCSDEAWCG
YHGAPL-----------------QGAPFS

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 341)

CDFEQDSCGWRDISTSGYRWLRDRAGAV-LA
GLGLHTDHTHGTDL--GWYMAVGTHPGKEASTATLRSPVLRQAAPACELRLWYLTASG--
-----GVAELRLELTHGTETLTLWQSSGPW-RPSWQELAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGTVALDDVAF

ENSGT00720000108445_1_Linker_0_1 (341, 354)

WNCALPSPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

RCPPGHH
HCRNGACVAPDSVCDGEDGCGDSSDEDPAT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHLMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGLWSRS-----------
----------EGWTRNHSAGGPQSLAWPLRDHSQNSAHGTFLASVAKP----GTPAVLSS
PVFQASDPYNCSLIFYYYLHGSEAGHLQLLLQTRGPGAPQAP-----SPLRRRHGELGAA
WVRDRVDIWSTHPFQI--LLAGETGP--GGVVGLDDLILSSHCRAAPGDLE--SM-----
---GPWPEPP-P------QPPWP-RPQDCEPGHLPCQD-LCVPPEQLCDFQPQCAEGEDE
QDCGEPGPGDP-CPEG-------QDPWLT-----------------S

PF00629 // ENSGT00720000108445_1_Domain_4 (708, 826)

LPLGHFLSLEKAW
GQLKAEARARTPALGPSGPHCELRMAYYFHGHPRGFLALVVVE--RGFRELVWQAPGS-G
SGSWTVDRVLLGARHRPFRLEFVGLLDLDGPGQQGAGVDNVTLKDCSPTVTTRKDQEVSC
NFERDACTWHTGHLTDAHWRRVESHGPGYDHTTGRAQPCFYMLLNPTDPPAQGQGAHLLT
GPQVPAAPEECFSFWYHLYGPQIGTLRLALRRDGEQDVQLWSRSGTHGNRWHQAWATLHH
QPGLSTKYQLLFEGLRDGYHGTMALDDMTVRPGPCWAPRS

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSACGFSSGGQGLWRR
QAHVTG-HVPW--GPWADHTTETAQ--------GHYMVVDTSPGALSQGQVAPLTSARHP
PLAQPSCLTFWYHLSPQNP-GTLR--VHVEDGER---RQVLSLSAHGGLAWRLGRVDMQA
EKTWRVVFEAVAAGVERSYMALDDLALHDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

ARPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHCTRASPGRYSW
DWSGASIPS-RYPQPTVDHTLGTQAGHFVLFETGVLGTGGRAAWLCSEPLPATA--ASCL
RFWYHMGFPEHFYKGELRVLLSSAQGQLAVWGEGGRLRQQWLQAQVELASTEEFQIVFEA
TLSGQPAEGPIALDDVEYLAGQHCQQPTPSQGDTTM-P-VPVPVPAAVGGALVFL-LLLV
-LLGLGARHWLQR------GCYFPRG-----TGAAAPGFDNILFNADRVTL-PESTTPDM
A-------------------

------------------------------------------------------------
--MCLPSHLLSTWVLFM-VTLPAAQSLGKTWLPNHCRSPIKAVCNFVCDCGDCSDETQCG
FHGASTIP----------------STSFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CNFEQDSCGWQDISTSGYRWLRDRAGAV-LH
GPGPHSDHTHGTDL--GWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHIASR--
-----DVAELRLDLTHGVETLTLWQTSGPW-GPGWQELAVNTGRIQGDFKV---------
-------------------TFSATRNATHRGAVALDDVEFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPIPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

RCPLGHH
HCQNKACVEPHQLCDGEDNCGDRSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQL-----------
----------EGWTRNHSAGSMVSPAWPHRDHSRNSAYGFFLISVAKP----GTTAVLYS
PEFQGSVSNNCSFTFYYYLHGSEASHFQLFLQAQGVNTPQAP-----VLLRSRHGELGTA
WVRDRVDIQSAHPFRI--LLAGETGP--GGVVGLDDLIMSSHCMLVPAMST--LQSSLS-
---GPVPLALYP------QTSIKLPQQTCEPGHLSCGD-LCVPPEQLCDFQKHCAEGEDE
HKCGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESA-SAGGWEDISVGKLQWQWVEAQEKSKPAGDA---DRDAPGHFLSLQKAW
GQLRSEARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVE--NGFRELLWQAPGG-S
SGSWTEEKIILGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CNPMMTTESDQELS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQ---GFFMFLDPTDPPARGQGALLLT
RPQVPVVPKECLSFWYRLYGPQIGTLCLAMRREGEETILLWSRSGTHGNRWHQAWVTLHH
QPEASTKYQLLFEGLRNGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTH
QSNASG-LVSW--GPWIDHTTGTAQ--------GHYMVVDTSPNVLPKGHVAALTSEEHQ
PLSQPACLTFWYHMSVPNP-GTLR--VHVEESTR---RQELSINAHGRSAWRLGSVNVQA
EQAWKVVFEAVAAGVEYSYMALDDISLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLPWPSLGGYSW
DWSSGATPS-RYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATT--VSCL
RFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGHLRDQWLQVQIEVSNSEEFQIVFEA
TLGGQPALGPIAIDDVQYLAGQQCKQPSPSQGEVTA-P---VSVPVAVGGALLFF-MFLV
-LMGLGGWHWLQK-Q----HCPGQRS-----TDAAASGFANILFNADHVTL-PESITSNP
QSPPDLA-------------

------------------------------------------------------------
--MPLPSHLLPA---L---VLLLVGSPGWAWVPNHCATPSDTLCDFVCDCGDCSDETHCG
YHATPSAL----------------GVPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFEQDTCGWRDISTSGYSWLRDRAGAA-RG
GPGPGSDHTRGTDL--GWYVAVGTHRGKAASTAALRSPVLREAAPACELRLWYHVASG--
-----DAAELRLELTHGTETLTLWQSSGPW-GPGWQELVVATGRIQGDFRV---------
-------------------TFSATRNATHRGAVTLDDMAFSGCG

ENSGT00720000108445_1_Linker_0_1 (345, 353)

LPSPQ---

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

ARCPLGQH
QCQNKACVEAQQLCDREDDCGDSSDEDVPS

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CRHHMS

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 578)

TDFETGLGLWNHS-----------
----------EGWTRNRSAGGPEHPAWPRRDHSRNSAQGYFLASVAEP----SAPATLYS
PELQASGPHNCSLTFYHYLHGSEATCLQLFLQTQRPGAPQAP-----VLLRRRRGELGAA
WVRDRVDIQSDHPFQI--LLAGYTGP--GGVVGXXXXXXXXXX-----XXXXXVSRPPL-
---ELWAPAPWL------QASGQQPQGFCELGHLSCGD-LCVPPEQLCDFQQQCEGGEDE
QQCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 836)

TDFETP-TAAGWEDASVGRLQWGRRQAQESGSSG--------ATAGHFLSLQRAW
GQLTAEARVLTAPLGPSGPHCELHLAYYFQSRS---------------------------
-------------------------------------------------------PEVSC
NFERDTCGWHTGHFTDAHWHRTESRGPGYDHTTGR---GYFMVLDPADPLARGPGAHLLT
RPQTPATGPECLSFWFHLHGPQAGTLRLVMRQDGKADTRLWSRSGSHGNRWHEAWATLSH
QVDSGAQYQLLFEGLRDGFHGTMALDDVAVRPGPCWAPEL

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CSFEDSACGFSTS--GLWTL
QTNATG-HAAW--GPGADHTTETAQ--------GHYMVVDTSPQALPQGRVASLTSEEHR
PLAQPACLTFWYHLSAQKP-GTLQ--VHVEEAGR---RQVLSISGHGGLAWSLGSVDVQA
QRAWRVVFEAVAAGVEHTYIALDDLFLQDGPCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

RPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFEMGLCGWSHLPSAGLGGYSW
DWSSGATPS-RYPQPPVDHTLGTDAGHFALFETGVLGPGGRAAWLRSQPLPATK--ASCL
RFWYYMGFPEHFYQGQLRVLQSSARGQLAVWGAGGRLRHQWLEGQVEVASAEEFQIVFDA
SLGGQPVLGPIGLDDIEYLAGQPCQLSAPSQGDTAGAT----LVPAAVGGALLVL-MLLV
-LLGVLGRHWLRKKG----GCPFRSR-----AEAKATGFDNVLFNADQVTL-PTSVTNDP
--------------------

------------------------------------------------------------
--MSLPGHLLPSLVLLV------AGFPGWAWVPNHCRSPGEAVCNFVCDCSDCSDEAQCG
HHGASAA----------------LGAPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEHDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPRSDHTLGTDL--GWYLAVGTHQGKEAATAVLRSPVLHEAAPTCELRLWYHLASG--
-----DAAELRLQLTHGAETLTLWRSSGPW-GPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVGLDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FRGCGLPSPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPPGHH
HCQNKACVEPHQLCDGEDNCGDLSDEDSPT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNHS-----------
----------EGWARNHSAGSPEHPAWPRRDHSWNSAKGYFLVSLAEP----GTPTVLSS
PKFQASSPHNCSLVFYRYLHGSEASCLQLFLQTLQPGAPPAP-----ILLRRHCRELGAA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVALDDLILSDRCKPVLEPAG--LQMLPP-
---APWAPAPET------PPSSLVPQNFCDPGHLSCGD-LCVPPEQLCDFQQQCAGAEDE
QDCGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-TAGGWEDASMGRLQWQLLAQE--------------AAGGRFLSLQRAW
GQLRPEARVLSPALGPSGPSCELHLAYHFQSQPRGFLALVVVD--GSSRELVWQAPGS-S
TGGWKVDKALLGARRRPFRLEFVGLVDLDGPGQQGAGVDNVTLRN

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTETTERDGEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYTGHLTDAHWHRVQSHGPGYDHTTGQ---GHFMLLDPTDPPARGYGAHLLC
RPQVPAAPVECLSFWYQLHGPQIGTLRLAMRREGE-DMLLWSRSGTHGNRWQEAWATLHH
QPSSRTRYQLLFEGLRDGYHGSMALDDVAVRPGPCWAPKRCSFEDSACGFSTGGQGLWKR
QTNASG-HAAW--GPRTDHTTETAQ--------GHYMVVDLSPDALPQGHVASLTSEEYR
PLAQPACLTFWYHLSLRSP-GTLR--VHVEEGGR---HPVLSISAHGGAAWRLGSVDVQA
RRAWRVVFEAVAAGVEPSYMALDDLFLQDGPCPKPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1344)

CDFESGLCGWSHLAWPGLGGYSW
DWSGGATPS-RYPHPAVDHSLGTEAGHFAFFETGVLGPGGQAAWLRSEPLPATQ--ASCL
RFWYHMGFPEHFYKGELRVLLVSTQGQLAVWSQGGHRRHQWLEAQVEVASAEEFQVVFEA
TLSGQPALGPIALDDIEYQAEQRCQQPAPSQGHMAT-P---VSVPAAVGGALLLL-MLLV
-LLGLGGRRCLRERG----GCPFWSG-----REAATPSFDNVLFNADHVTL-PESVTSDP
QATT----------------

------------------------------------------------------------
--MHLPA----LLPTL---ALLAAGSLGGAWVPGRCRRPREAECDFVCDCADCSDEAQCG
YRAAAPAP----------------GAPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEWDLCGWRDISTSGYSWLRDRAGAA-PE
GSGPRADHTRGTDL--GWYVAVGAHRGKEASRAVLRSPDLREAAPSCEIRLWYHTGSA--
-----DVAELRLELTHGAETLTLWQSPGPW-GPGWQELAVATGRIRGPFWV---------
-------------------TFSAIRNATHRGAMALDDVAFWDCGLPSKTPPASSPGR---
-------------------------------------GVRL-------------------
------------------------------------GQGLA-------------------
--LPTTTPPAPQ

PF00629 // ENSGT00720000108445_1_Domain_2 (493, 584)

LVFYHYLHGSEAGSLQLFLQPQSPGAPQAP-----VLLRSRRGELGAA
WVRDRVDVQSAHPFRI--LLAGHTGP--GGVVGLDDLILSDHCALVPEAPAQRVLPP---
-----------A------PPRPLPPRGACAPGHLSCGD-ACVPPEQLCDFQRQCDGGEDE
RQCGST

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 756)

DFEA--TAGGWEDASVGRLQWR-LARQKSGRPGSNA---VRVAAGHFLSLQRAW
GQLAAAARALTPPLGPSGPRCELHLSYYLQSRPRG

ENSGT00720000108445_1_Linker_4_5 (756, 812)

TTW---------------PLGGGGS
GGGGGEPRAPLRPHHRPR------LVRPAQP

PF00629 // ENSGT00720000108445_1_Domain_5 (812, 996)

GPPG-------------------------
------------------------PAALQLHLALS---GHFVLLNPTEPQARGPAAQLLS
RAQVPAAPTECLSFWYHLYGPQIGTLRLVMRRQGEGDVQLWARSGTHGNRWHQAWATLHH
RPDSSGKYQLLFEGLRDGYHGTMALDDIAVRPGPCWAPRRCSFEDSSCGFTAGGQSVWHR
AS-AGS-QASQ--GPRTDHTTETAQ--------GHYMVVDTSPEALPPGHVATLTSEEHR
PLAQPSCLTFWYHLSLRQP-GVLR--VHMEEGAR---RQLLSIRAHGGLAWRLASVDVQA
EQAWRVVFEAEATGVEHSYVAVDDLLLQDRPCAQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CAFESGLCGWSHMPWPGLGGYSW
DWSSGATPS-RYPQPSVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATT--AACL
HFWYHMGFPEHFYKGELRVLLSSARGQLAVWGAGAHQRHQWLEGQVEVASSEEFQIVFEA
TLGGQPALGPIALDDVEYLPGQHCPRPATSQGELAVPV----SVPAVVGGALLVL-ALLV
-ALGSAARCWLWRGR----GFPFQKD-----QAAAPPGFDNILFNSDHVTI-PEPVPSDQ
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAVCNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLRDAAPSCQLRLWYHAASG--
-----DVAELRLEVTHGSETLILWQSTGPW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPELPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVLEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAV-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTERDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAVPTECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGTRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHHCSFEDSDCGFSSGGQGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWRLGSVDVQA
QRGWRVVFEAVAAGVAHSYVALDDLLLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGA-PS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--VSCL
RFWYHMGFPEHFYKGELRVLLSSAQGQLAVWSTGGHRRHQWLEAQVEVASTNEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAV-P---VSVPTVVGSALLLL-MLLV
-LLGLGGRRWLK-RG----SCPFQSN-----TEATAPSFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
-----------MISHLV-VALPATLSPGKTWIPSNCRSPCEAMCNFVCDCRDCSDESQCG
FHGALPTP----------------GAPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 296)

CSFEQDACGWRDISTSGYSWLRDRAGAV-LG
GPRPHFDHTQGTDL--GWYMAVGTHRGKEASTATLRSPVLREAAATCELRLWYHAASGGA
WEGSLYVAELRLELTHGVETLTLWQSSGPW-GPGWQELAVNTGRIQGDFQVSWIG

ENSGT00720000108445_1_Linker_0_1 (296, 354)

WTAQP
G-------------------------------------AVRRC--EIPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKACVATHQLCDGEDSCGDSSDEGPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHVVT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNHS-----------
----------DGWTLNHNAGGSVGPAWPSRDHSHNSAQGSFLVSMAKP----GNLAVLSS
PEFQASDPYNCSLIFYYYLHGSEASRLQLLVQALGSSDSQAP-----VLLRSRHGELGAA
WVRDQVDIRSPHPFQI--LLVGETGP--GGVIGLDDLILSNYCRLVPEVSV--PQSLLP-
---GPNTLVPWT------QPSIQEPQNVCKPGHLSCGE-LCVPPEQLCDFQQQCTEGEDE
RECGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFESA-SAGGWEDASVGRLQWQRLEAKDSREPSRDT---SRASDGHFLSLQKAW
GQLRPEARTHTPTLGPSGPSCELHMAYYFHSHPQGFLALVVVE--RGSRELLWQAPSS-S
SGKWTVNKVLLGARPRPFQLEFIGLVDFDSPGQQGAGVDNVTLRNCNPTVTADNDQEVSC
NFERDECSWHTGHLTDAHWHRIKSFGPGYDHTTGQ---GFFMFMDPMDPLARGQGAHLLT
RPQIPAVPKECLSFWYHMYGPQIGTLRLVLRRDGEEGTQLWTRSGTHGNRWHQAWVTLHH
QLEPSTKYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPKR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSPGGQSLWMR
QGNASG-QAPW--GPWSDHTTETVQ--------GYYMVVDTSPNALPKGHVASLTSEEHQ
PLAQPACLTFWYHLSLHKT-GTLR--VHVEEGTR---RQVLSISAHGGFAWRLGSVNVQA
ERAWRVVFEAVAMGVEHSYVALDDLFLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

TQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGSYSW
DWSSGATPS-RYLQPTVDHTLGTEAGHFAFFETSVLGPGGRAAWLRSEPLPATE--ASCI
RFWYYMGFPEHFYKGELRVLLSSARGQLAVWGEGGRLQHQWLQVQIEVASTEEFQIVFEA
TLGGQPALGPIALDDVEYLAEQHCQQPTPSQGDVAP-P---LSVPAAVGGALLFL-VLLM
-LLGLGGWHWLQR-M----GCPFRRG-----ADTATSGFDNILFNADQVTL-PAPASATS
NP------------------

------------------------------------------------------------
--MHLPRHFLPTLVLLV-VTLPATWSPCKAWVPNHCRSPSKAVCNFVCDCRDCSDESQCG
FHSAL--PT--------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CNFEQDPCGWQDISTSGYSWLRDRAGAV-FD
GPGPHSDHTHGSDL--GWYMAVGTHRGKETSTATLRSPVLHEAAPTCELRLWYHAVSR--
-----DVAELRLELTHGVETLNLWQSSGPW-GSGWQELAVNTGRIRGDFRV---------
-------------------TFSVTRNATHRGAVAVDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWNCGLPIPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

SCPMGHH
HCQNKACVEPHQLCDNEDNCGDGSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDLLICSHHMLT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGLWNHS-----------
----------QGWAWNHSAVSSVIPAWPHRDHSQNSAHGSFLVSLAKP----GTPAVLFS
PEFQASGSFNCSLTFYYYLHGSEAGRLQLLLQAQGSKTPKVP-----ILLRSRHGELGAA
WVRDRVDIQSAHPFQI--LLTGETGP--GGIVGLDDLILSNHCRPVPEVST--LQLSLP-
---GPGAPVLFP------QPSTQSLRNVCEPGHLSCGD-LCVPPEHLCDFQQQCTEGEDE
RECGA

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFEST-SAGGWEDISVGQLQWKLVEAHESREPARDA---NRAAAGHFLSLKKAW
GQLRAEARALTPALGPSGPHCELHMAYYFHSHPQGFLSLMVVE--NGFRELLWQAPSS-S
SGGWTANKVLLGAHHRPFQLEFVSLVDLDGPGQQGAGVDNVTMKN

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CNPMVTTENDQDIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDECSWHTGHLTDAHWQRIKSHGPGYDHTTGQ---GFFMFLDPMDPPAHGQAAHLLT
RPQVPAIPKECLSFWYHLYGPQIGTLRLAMRRDK-EDILLWSRSGTHGNRWRQAWVTLHH
QPEASTKYQLLFEGLRDGYHGTMALDDMAVRPGPCWAPKSCSFEDTACGFSPGGSGLWIH
QGNASG-HAPW--GPWTDHTTETPQ--------GHYMVVDTSPHALPKGHVASLTSEQHQ
PLARPACLTFWYHMSLRNP-GTLR--VHVEEGTS---RQELSISAHGGFAWHLGSVNVQA
KEAWRVVIEAVAAGVEHSYMALDDLFLQDGPCAQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGRYSW
DWSSGATPS-RYPQPTVDHTLGTEAGHFAFFETSVLGPGSQAAWLRSEPLPATT--ASCL
CFWYYMGFPEHFYKGELRVLLSSAQGQLAVWGEGGRLRHQWLQVQIEVASSEEFQIVFEA
TLGGQPALGPIAIDDVEYLPGQHCQQPTPSQGDMAA-P---LSVPAAVGGALLFL-VLLV
-LLGLGSWHWLHK-W----GCPFQRS-----TETAASSFDNILFNADQVTL-PASVTSNP
VTAGKAW-------------

MLGPSHTQAPHPDSLSKARHALLGPDRDPRGQFSVGSWPPPCTASWPGAQMSQGAWLLGV
SGLRNSGASLPLATWL---SLLAAGSPGWAWVPNHCRAPREAACNFVCDCRGCPDEAQCG
YHGVSPSP----------------GAPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFERDSCGWQDISTAGYRWLRDRAGAS-PQ
GPRLRSDHTLGTDL--GWYVAVGTHRGRETATAALRSPVLHEAAPTCELRLWYHVASG--
-----DVAELRLELTHGAETLTLWRSPGPW-GPDWQELVVPTGRIQGAFRV---------
-------------------TFSATRNATHRGTVALDDVA

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWRCGLPTSQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 389)

HCPLGHH
HCRNEACVEHPQLCDGEDNCGDRSDEDA

ENSGT00720000108445_1_Linker_1_2 (389, 398)

ALCRHYVAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFEMGLGLWNHS-----------
----------EGWTRNRSAGSPGLPAWPRGDHTWNSAQGSFLASVAEP----SAPAVLSS
PKFQASAPHNCSLVFYHYLHGSEAGCLQVFLQTASPAAPQTP-----ILLRRRHGELGAA
WVRDRVDIQSRHPFRI--LLAGQTGP--GGVVGLDDLILSDHCKPIP-----ELASPPP-
---GCWAPGPWP------QPSSLRPRSFCEPGHFFCGD-LCVPPEQLCDFQQQCPGGEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 824)

DFESP-SGGGWEDASVGRLQWARLPAPDRGGPGPDA---RR-AAGHFLAVQRAW
GQLAEEARVLTPTLGPSGPRCELRLVYYLQSHPQGFLELVVVE--GSRRELVWQALGSTA
GG-WKVDRVLLGARRRPFRLELVGLVDVDGPGQQGAGVDDVTL

ENSGT00720000108445_1_Linker_4_5 (824, 840)

MGCSPAAATEEDSEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERGACGWHTGHLTDAHWQRVESRGPRYDHTTGQ---GHFVLLDPTDPPAWGPAAHLLT
QPRVPSAPQECLSFWFHLFGPQIGTLRLVMRREGEAEAHLWSRSGTHGNRWHEAWATLHH
QPDAGAKYQLLFEGLRDGYHGSMALDDVTLRPGPCWAPRRCSFEDSACGFSVGGRGLWTR
LAN-----ASW--GPHADHTTETAQ--------GHYMVVDTSPQALPRGHAALLTSEEQR
PLVQPTCLSFWYHLSLRNP-GTLR--VHVEEAGR---QQVLSVSSRGGATWRLGSVDLQA
RQAWRVVFEAVAAGVEHSYMALDDLLLQDGPCPLPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWNHVPRPGLGGYSW
DWSSGASPS-RYLQPPVDHTLGTEAGHFALFETSVLGPGSRAAGLISQPLPPTA--ASCL
RFWYHVGFPEHFYQGELRVVLSSAQGQLAVWGAGGRRRHQWLEGQVDVASAAEFQIVFEA
TLGGQPALGPIALDDIEYLAGQRCQLPTPSQGGGAAAA----AVPAAVGGTLLLLLLLLL
-LLGVAGRRWLQK-A----GCPSRGE-----VDAVAPGFENILFSADRVTL-PASVTNDQ
--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MSSPPP-
---GLWAPAPGP------QLSSLRPQDFCEPGHLSCGD-LCVPPEQLCDFQHQCEAGEDE
QECGTS

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 827)

DFEPP-AAGGWEDASVGRLQWGRLQAQESGGPGAGG---SGAAAGHFLSLQRAW
GQLTPEARVLTPPLGPSGPRCKLRMAYYFHGDPQGFLALVVVE--GGRREPVWQAPSS-S
GD-WKADTVLIGARRRPFRLEFVSLVDLDGPGQQGAAVDDVTLEDCSPVTATEKDSEVSC
NFERDTCGWHSGHLTDAHWRRIESRGPGYDHTTGQ---GYYLLLDPTDPPARGPGAHLLT
QPQAPAATQECLSFWYHLHGPQIGTLRLAVRREGEAETLLWSRSGTHGNCWHKAWATLHH
QAGSGAKYQLLFQGLRDGYHGTMALDDVAVRPGPCWASRR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSACGFSSSGQGLWTR
QTNATG-HASW--GPRTDHTTETAQ--------GHYMVVDMSPHALPRGHVASLTSEEHQ
PLTQPACLTFWYHLSLRNP-GTLQ--VHVEEAGR---QQVLSLSAHGGFAWRLGSVDVQA
ERAWRVVFEAVAAGVERSYIALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PRPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWSHLPWPSLGGFSW
DWSSGATPS-RYPQPPVDHTLGTEAGHFVLFETGVLGPGGRAAWLRSQPLPATE--SSCL
RFWYHVGFPEHFYKGELRVILSSAQGQLAVWSAGAHRRHQWLEGHVEVVSAEEFQIVFEA
TLSGQPALGPIALDDVEYLAGQPCQRLTSSQGDTALAA----SVPTIVGSALLVL-IVLV
-LIGLGGWRWLQKER----SCPSRAE-----TAAVAPGFDNIVFNADHVTL-PASLTDPQ
--------------------

------------------------------------------------------------
--MPLPGHLLPILVLFL------AGSPGWAWVPNHCRSPSQAMCNFVCDCRDCSDEAQCG
HHGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFERDPCGWRDISTSGYSWLRDRAGAV-LE
GPGPRADHTLGTDL--GWYMAVGTHRGKEAATAALRSPTLREAAPSCKLRLWYHMASG--
-----DVAELRLELTHGAETLTLWQSTGPW-CPGWQELAVTTGRIRGDFRV---------
-------------------IFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLSTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLEHH
HCHNKACVEPQQLCDGEDNCGDLSDEDPRT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGQHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

NFETGLGLWSRS-----------
----------EGWARNHSAGGTEHPAWPCRDHSRNSAQGSFLVSVAEP----GNPAVLSS
PELQASGTSSCSLIFYYYLHGSEASCLQLFLQTLGSSNPQAP-----VLLRRHRGELGTA
WVRDRVDIQSAYPFQI--LLAGQTGP--GGVVGLDDLILSEHCRPVLEVST--PQPLPP-
---GPWVPAPGP------LPPSSRLQDFCQQGHLACGD-LCVAPEQLCDFEQQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWRRLSARE----GAAA-------AGHFLSLQRAW
GQLGAEARVRTPPLGPSGPSCELHLAYHLQSQPRGFLALVVVD--SGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRDCSSMVTTKRDTEVSC
NFERDTCSWYPGHLSDTHWRRVESRGPEHDHTTGQ---GYFMLLDPTDPLARGHSAHLLS
RPQIPAVPTECLSFWYHLHGPQIGTLRLAMRREGE-DTHLWSRSGTHGNRWHQAWATLSH
QPGSRAPYQLLFEGLRDGYHGTMALDDVAMRPGPCWAPDY

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CTFEDSDCGFSPGGQSLWKR
QANASG-HAAW--GPPADHTTETAQ--------GHYMMVDTSPDALPRGQTASLTSREHR
PLAQPACLTFWYHGSLLSP-GALQ--VHLEEGRR---HQVLSLSAHEGLAWHLGSVDVQA
EQAWRVVFEAVGTGVAHSYMALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PQPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLARPGLGGYSW
DWGGGATPS-RYLQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELRVLLCSAQGQLAVWSTGGHRRHQWLEAQVEVASTKEFQIVFEA
TLGGQPALGPIGLDDVEYLAGQHCQQPAPSPGDTAT-P---VPVPAVVGGALLFL-MLLV
-LLGLGGQRWLEKRG----SCPFRSD-----TEATAPGFDNILFNADGVTL-PASVTSDL
--------------------

------------------------------------------------------------
--MPLSSHLLPALVLFL------AGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCG
YHGASPT----------------LGAPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASG--
-----DVAELRVELTHGAETLTLWQSTGPW-GPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

NCPPGHH
HCQNKVCVEPQQLCDGEDNCGDLSDENPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAP-----VLLRRRRGELGTA
WVRDRVDIQSAYPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVSEVST--LQPLPP-
---GPRAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 753)

DFESP-EAGGWEDASVGRLQWRRVSAQESQGSSAAA-------AGHFLSLQRAW
GQLGAEARVLTPLLGPSGPSCELHLAYYLQSQ

ENSGT00720000108445_1_Linker_4_5 (753, 840)

PR--------------------------
--------------------------------------------------------EVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRR
QANASG-HAAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLRSP-GTLR--VYLEERGR---HQVLSLSAHGGLAWRLGSMDVQA
ERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAA-P---GSVPAVVGSALLLL-MLLV
-LLGLGGRRWLQKKG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--MPLPGHLLPILVLFL------AGSPGWAWVPSHCRSPSQAVCNFVCDCGDCSDEAQCG
YHGASPA----------------PGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFERDACGWRDISTSGYSWLRDRAGAA-LE
GPGPRSDHTLGTDL--GWYMAVGTHQGKEAATAALRSPTLREAAPSCKLRLWYHMASG--
-----DVAELRLELTHGAETLTLWQSTGSW-GPGWQELAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCWLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKACVEPQQLCDGEDNCGDLSDEDPRT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGQHTVT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGLWSRS-----------
----------EGWARNHSAGGLEHPAWPCRDHSRNSAQGYFLVSVAEP----GNPAVLSS
PELQASGASSCSLVFYYYLHGSEAGCLQLFLQTLGSSTPQAP-----VLLRRRRGELGTA
WVRDRIDIQSAHPFQI--LLTGQTGP--GGVVGLDDLILSEHCRPVPEVST--PQPLPP-
---GPWAPAPGP------LPPSSRLQDFCQQGHLACGD-LCVPPEQLCDFQQQCAGNEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWQRLSAQESQGAGAAA-------TGHFLSLQRAW
GQLGAEARVLTPLLGPSGPSCELHLAYHLQSQPQGFLALVVVD--SGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFRLEFVGLVDLDSPYQQGAGVDNVTLRDCSPMVTTKRDREVSC
NFERDTCSWYPSHLSDAHWHRVESRGPKHDHTTGQ---GYFMLLDPTDPLARGHSAHLLS
RPQVPAAPTECLSFWYHLHGPQIGTLRLDMRREGE-DTHLWSRSGTHGNRWHQAWATLSH
QPGSRAPYQLLFEGLRDGYHGTMALDDVAMRPGPCWAPDY

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSPGGQSLWRR
QTNASG-HAAW--GPPADHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSREHR
PLAQPACLTFWYHGSLFSP-GALQ--VHLEEGRR---YQVLSLSAHEGLAWRLGSVDVQA
EQAWRVMFEAVGTGVAHSYVAVDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWNHLARPGLGGYSW
DWGGGAAPS-RYLQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--VSCL
RFWYHMGFPEHFYKGELRVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGGQPALGPIGLDDVEYLAGQHCQQPAPSPGDTAT-P---VPVPAVVGGALLFL-MFLV
-LLGLGGRRWLQKRG----SCPFQSS-----TETTAPNFDNILFNVSVTSD-L-------
--------------------

------------------------------------------------------------
--MWLPAYLLPALVLLM-GEWAAAQALGRAWASSPCQSPVEAQCDFLCNCRDCSDETQCG
YRVASPS----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWQDISTSGYSWVRDRAGAQ-PE
GPVAHADHTRGTDL--GWYMAVGTHLGTEASIAALRSPVLREAGPACELRLWYQAASG--
-----DVAELQLELTHRAETLTLWRSSGPW-RPGWQALAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

TCPVGHH
HCQNAACIESHQLCDREDNCGDGSDEDLLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGLWTHS-----------
----------EGPAWNHSTGSPKGSAWPSRDHSRNSAQGSFLVSTAKP----GSPAVLLS
PQLQASGSHNCSLIFYHYLHGSEDGRLQLLLHTQGPRASQAP-----VLLRQRQGELGAA
WVRDQVDVRSAQPFWI--LLTGETGP--GGVVGLDDLILSDHCTVA-----------PG-
---DPWPKAPWP------QQSS--LQGSCQPGQLACGD-LCVPLEQLCDFQPQCAQGEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESA-TAGGWEDASVGRLQWVRLAAQERGGP-------GRTAAGHFLSVQRAW
GQLRAEARALTPVLGPSGPHCELHMAYYFHSRPRGFLALAVVD--SGSRELVWQAPGG-S
SWDWTLDKVLLGAHRRPFQLELVALLDLDGPGQQGAGVDNVTMRN

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTEKDREVT

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDACGWHLSHLTDVHWHRVESHSSGYDHTTGQ---GFFMLLDPTNPLSRDHHAHLLT
EPQVPAALDQCLGFWFLLHGPQIGTLRLAMRRNKEEEVQLWSGSGTHGNRWHQAWATLNH
QLEPSTKYQLLFQGLRDGYHGIMALDDVTLQPGTCPAPQRCSFEESACSFSSGGQGLWRR
QASAWG-HAAR--GPWTDHTTETAQ--------GHYMVVDTSPDVLPRGHMASLTSEEHW
ALPRPACLTFWYHLSLQSP-GTLQ--VRVEEGGR---HQTLSISEHGALAWRLGSMDVHA
EQAWRVVFEAVAAGVEHSYIALDDVFLQDGPCPQPGGR-----LCGLWPHSWGSTGPR--
---------------GHSLHLLLF

PF00629 // ENSGT00720000108445_1_Domain_8 (1225, 1345)

PGHFAFFETGVLGAGGRAAWLRSEPLPATA--ASCL
RFWYLMGFPEHFYKGELHVLLASSRGRLEVWAAGGRLRHQWLEAQVEVASDEEFQVVFEA
TLGGQPVQGPIALDDIEYLAGQHCQWPAPSPGEHWDTA-AHVSVLAAVSGALVFL-VLLV
-LLGLAGRHWLQKSG--GWGWPFQRD-----KDLAAPGFDNILFSADQVTL-PAAVTSDP
--------------------

------------------------------------------------------------
--------KCQGQSLSGWATLMALLSMSRAAAINSCGSVAEQHCDFVCHCGDCSDENQCG
YLGISTVL----------------RSPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFEDDDCGWRDVSTSTYRWVRGRASLD-SW
GTGPHSDHTMGTDR--GWFMVTMSPPAKATATAWLQSPVMQEATAMCEIWASYHLSGSGL
--NQTACPVLRLTAAFGNTVVELWRSSEH-RAEGWHQLVAYPGRIKGQFQL---------
-------------------TFALTQQPTCGAVLALDDIVFRNCG

ENSGT00720000108445_1_Linker_0_1 (345, 353)

LP---AGQ

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

QSCEAEES
NCSKGSCLALDRFCDGTDDCGDGSDEDAEQ

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CQLFTF

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 585)

CSFEED------------------
LCSWEAEAGQPAWGRNTSMGLGTTSGVPTRDHSTNSATGYFLHTITASSV-----ARLSS
PTFQA--TNSCSLVLYCHLHGSAISSLSISYVINST----------EHLVRERTGDTGSC
WVRERVDFNLTESFKV--LITGEAGS--GGTVAVDDLVLSPGCV

ENSGT00720000108445_1_Linker_2_3 (585, 627)

LQQVPPSSPGLLPS--
--------EPAP-----MELPGWARA

PF00057 // ENSGT00720000108445_1_Domain_3 (627, 663)

SPCAAEEFSCDDGGCVSAELACDFAKACADGSDE
NN

ENSGT00720000108445_1_Linker_3_4 (663, 666)

CGA

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 828)

TTFEE--GAGGWHDTSVGQLRWAWVEECPRGRGRGDGNRGLFPCPGAFLALQRGE
GQMVAPAKVRTPLLGPSGLACAMEMSYILHSGPQGFLAVAVMEHSTDMTHLAWHMRGH-G
STTWEHVHVPLGERTRPFQVELLGMAELQDP--AEIAIDNVTFVQCD

ENSGT00720000108445_1_Linker_4_5 (828, 840)

PGTEPLGAAELS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 997)

C
NFEADLCGWYQDRGSDFQWVRSTGQGQGSDHTTGS---GYFLAADPSAPWSRGQCAQLIT
YSQEPAAAPRCLTFWYRLAGPQIGTLSLKLQLQGAEETVLWTQRGSQGSVWHRGLATLPA
TGQQHYRRQLAFEALRDGFVGDVALDDVALTAGACGAELSCSFEAGACGLAGSGQ--WWW
QSGGTG-I-TT--GPVADHTTGTTT--------GHYMVVNTSKHSLPMGHVATLSSALYR
RSVPAQCLAFWYQLSAAAPAGTLH--VLVEENGE--QRKLFSISAMEGDTWHRGHVTVQA
DTDWKVVFEAVGAGNEHSYMALDDLHVSDGACPEPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1266)

CDFEWDTCGWSSPSDERLHGFAW
GWKSGVPLA-KYPGPKQDHTLGTEDGHYMHFDTRVLGAGGTAARLESQHLPATT--AGCL
HFWYHMDIPEHL------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

------------------------------------------------------------
--MPLPGHLLP--ALV---LLL-AGSLGWAWVPNRCRAPREAVCNFVCDCRGCPDEAQCG
YHGAPPAP----------------GTPFS

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEQDFCGWRDISTSGYSWLRERAGAA-PG
GPGPRSDHTLGTDL--GWYAAVGTHRGKEAATAALRSPVLHEAAPTCELRLWYHAASG--
-----DVAELRLELTHGAETLTLWQSSGPW-RPGWQELLVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDMAFGR

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

RCPLGHH
HCQNKACVQPHQLCDGEDNCGDRSDEDTPT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHLAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 569)

DFEMGLGLWNHS-----------
----------EGWARNHSTGRPQHPAWPRGDHSRNSAQGSFLVSTAEP----SDPAILSS
PEFQASAPHNCSLVFYHYLHGSEAGCLQVFLQARSSGAPQTP-----VLLRGRRGELGAA
WVRDRVDIQSGRPFRV--RLVGAVGG--EGMQGQA-----EPCPPDPSSAPTEGSGPPP-
---G-----PWP------QPFSLQPRNFCEPGHLFCED-LCVPPEQLCDFQQQCLGGEDE
QECGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFEDP-SAGGWEDASVGRLQWMRVSAQASRIPGADA---AGNVAGHFLSLQRAW
GQLTEEARVLTPLLGPSGPRCELHLAYYFQSQPQGFLELVVVE--GSRRELVWQAPVHSP
VG-WKMDTILLGARHRPFRLEFVGLVDLDGPGQQGAGVDHVTLKDCSPTVATEKDAEVSC
NFERDTCSWHTDHLTDAHWRRVESQGPRFDHTTGR---GYFMLLDPTEPPAQGPSAHLLT
QPQAPTAPQECLSFWYHLHGPQIGTLRLAMRREGEADTHLWLRSGTHGNRWHEAWATLHH
PQDTSAKYQLLFEGLRDGYHGTMALDDVAVRPGPCSAPKR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSACGFSTGGQGLWTR
QTNATG-HAAW--GPHADHTTETAQ--------GHYMVVDMSPQALPRGHVASLTSEAHR
PLAQPACLTFWYHLSLRNP-GTLR--VHVEEAKR---RQVLSISTHGGFAWRLGSVDVQA
ERAWRVVFEAVAAGVERAYIALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PRPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWHHLPWPGLGGYSW
DWSSGATPS-RYRQPPVDHTLGTEKGHFALFETGVLGPGGRAAWLRSQPLPATE--VSCL
RFWYHMGFPEHFYKGELRVLLSSAQGQLAVWGTGGHLRHQWLEGRVQVASAEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQQPAPSQGDRAVAT----SVPAMVGSALLLL-AVLV
-LLGLVGRRWLRKRA----GCPSGGE-----SEAPAPGFDNILFNADGITL-PASVTTEQ
--------------------

------------------------------------------------------------
--MPPPSHLLPAVVLLL------ARSPGWAWVPSHCRSPGQAACNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGSW-DLGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHGGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSWNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPAPQP------LPPSSRFQDSCKQGHFACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDTSVGRLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGAHRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRDCSPTVTTKRDREVSC
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYYLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHH

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSSGGRGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWRLGSVDVQA
EQAWRVVFEAVAAGVAHSYVALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTKAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYYVGFPEHFYKGELRVLLRSAQGQLAVWGTGGHRRHQWLEAQVEVASTKEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQAAPSPGDTAA-P---VSVPTAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSEP
--------------------

---------------------------------------IVMGERWRGTQN---------
-------QLL--------AFSSLANTFVQSVLASHSSSPRKTTCNFVCDFWDCSDESQCG
YHQEYSSL----------------HSPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 342)

CDFEEDTCGWQDISTSGYRWLRDQAGST-FG
SPELRSDHTFGTDL--GWFMVVGTHQGKEPATAILRSPVLHEAAPTCEIRLRYHGNIQ--
-----DVVNLQIELTHNSETLMLWQSLGRVGGSGWQELVVTTGRIQGDFWI---------
-------------------TISATRNATHRGAMALDDMEFW

ENSGT00720000108445_1_Linker_0_1 (342, 354)

NCGLPSPQ---S

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCTSSQQ
HCNNYACVALTQLCDGEDNCGDASDENQVS

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CINHKIT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFENGLGEWENT-----------
----------TGWVITRGSEASVASAEPVRDHSKNSASGSFLLTKADQ----GTPAVLVS
PGFHPSTTNSCVFTFYYYLHGSEAGSLQLFLQSQDPESHQMN------LIRTRQGDLGAA
WVRDKVTLYSKNPFWI--LLKGETGP--GGVVGLDDLILNQHCKQVSKVEDIRP-PATS-
-----APDMPQH-HQGTKTGPRTPADIFCEPGQFSCGE-LCLSPEQLCDFVPQCAGGVDE
ENCGGT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 827)

NFE--SGPGGWRDASVGSLQWQRIRAQDSSDPKTDA---LGNEAGYFLSVQRAW
GQLMGVARVRTPVLGPSGPGCTLKMAYYLQGNPQGILSLGVIE--DGTHKLAWSIQRN-S
NATWTWVTVPLGERMRPFQLELLGLVVFSAPGTKGIAVDEITFVNCNPTVTTEKDTELSC
NFERDSCGWYPEHKTDALWRRTSVQGPGYDHTTSQ---GHFMYLDPTSPPARGMGARLLT
APQVSPAHNECLSFWYHLYGPQIGTLSLTLRRTGEADTHLWARTGTHGNRWHQAWATLSH
PSDSSEKYQLAFEAHRNGYHGNIAVDDITVRPGPCWAPRR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CSFENSDCGFLSSGQGAWQR
RGNATG-STIK--GPRADHTTETRE--------GHYMIVDTSPSALPQGQTALLTSEEYS
PLAQPGCLTFWYHLSLQNP-GTFR--VHVDEGKR---RQVFSVNAPGGFAWRLGSVDVQP
EKAWKVVFEAVGAGVEHTYMAVDDLYLKDGLCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

QPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESDMCSWSHTAWTDLGGYSW
DWSSGAIPS-RYPQPSVDHTLGTETGHFAFFDTSVLGPGGRAAWLQSEPLPPTPTGGSCL
RFWYYMGFPEHFYKGELKVLLLSSQGLLILWGTEAYLRQQWLEGHVQVTSPVEFQIIFEA
TLGGQPVLGPIALDDIVYQAGRSCEPPVPTRED-SKSA----TIPVVTV--TLLAALLLG
-LLAFGMWRRMKKG-----DHPFKKQEE----TTAASGFDNVVFNSDHVTL-PPITGDQT
TTPDAV--------------

------------------------------------------------------------
--MRPPGPLLPALVLL-----VAAWSPGWAWLLDYCRSPSKATCNFVCDYRDCSDEAQCG
YHGALPIP----------------GTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CGFEQDTCGWQDISTSGYSWLRDRAGAM-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPVLQEAAPTCELRLWYHAASG--
-----DVAELRLELTHGTETLTLWKSAGPW-GPSWQELVVTTGRIQGDFQV---------
-------------------TFSATRNATHKGAVAVDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWGCGLPVPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
QCQNKACIEPHQLCDREDNCGDGSDEDLLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFESGLGSWNHS-----------
----------EGWTRNHSAGGPEDRAWPNRDHSWNSAQGMFLVSMAKS----GTPAVLSS
PEFQASGSHNCSLIFYYYLHGSEVGCLQLLLQMQGPSAPQNP-----VLLRRHCGELGAV
WVRDRVDIRSAHPFQI--LLAGETGP--GGVVGLDDLILSDHCRTAPGRSD--LQSLPT-
---RPWVQALQP------QPSSFYPQEVCELGYLSCGD-LCVPPEQLCDFQEQCPEGEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFEAA-TAGGWEDASVGQLQWQRAAAQESRGPGRDA---RGAAAGHFLSLQKAW
GQLRPEARALTSPLGPSGPNCELHMAYYFHSHPQGFLALVVLQ--GSSRELVWQAPSS-S
TGDWTVDKVLLGARHRPFRLEFVSLVDWDIPGQQGAGVDNVTMRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSLTATTEKDQEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERNTCGWHMGHFTDAHWRRIQSHGPGYDHTTGQ---GFFMLLDPTNPPARGRAAHLLT
RPQTPATPKECLSFWYHLYGPQIGTLRLIMRRDGEEDMLLWSRSGTHGNRWHQAWATLHH
QLEPSTKYQLLFEGLRDGYHGTMGLDDVAVRPGPCWAPRHCSFEDSACGFSTGGQGLWKR
QANA-----SW--GPQTDHTTETAQ--------GHYMVVDTSPVALPQGHVASLTSEEHQ
PLAQPTCLSFWYHLSLHNP-GTLR--VHVEEGKR---RQVFSVYGHGGLAWRLGSVDVQA
GQAWRVVFEALAAGMEHSYIALDDLSLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGRYSW
DWSGGDTPS-RYPLPTVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATT--ASCL
RFWYHMGFPEHFYKGELRVLLSSAQGQLAVWGKGGHLRHQWLEVQVEVTSTEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQRPALSQGGMTA-S---MMVPALVGGALLFL-ILLV
-LLGLGGRHWLQK-G----GCPFRSN-----KDVAAPGFDNILFNADGVTL-PAPATSSS
TIPDKDLAR-----------

------------------------------------------------------------
----RCLGSCSLQPCCCWLGGLGGTPLSGSWRSNSCSSTAEHLCNFVCYCSDCSDENQCG
YLGVSTVL----------------GTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFEEGDCGWQDVSTTAYRWVRGQASLD-KW
GTGLHSDHTVGTDR--GWFMVTVSPPAKATATAWLRSPVMQDVAATCEIWASYHLSGS--
-----TCPTLRLTMASRDKVVELWQSPQH-GAEGWHQLVAYTGRITEQFQL---------
-------------------TFALTQPPACGAVLALDDIVFRNCGLQTPAPGQQVCGAEES
RCSQGSYLAPNRFCDGTDDCGDSSDETAQHCQNFNN

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 586)

CSFENG------------------
FCNWV-EAGQMTWERNTSMKLGDTYGIPTRDHSTNSAAGYFLHISSASAAGSSSTASMST
SIISS--NSSCYLVLYCHLHGSATNSLSISYMTNST----------EQLVRQRTGDTGNC
WVRERVDFNVTESFKV--LIKGVARS--GGTVAIDDLILSPGCTP

ENSGT00720000108445_1_Linker_2_3 (586, 627)

HLVLHSSLGLSPS--
--------DPSP-----TALPRQDRA

PF00057 // ENSGT00720000108445_1_Domain_3 (627, 663)

STCMAGEFTCDDGSCISSELACDFAKTCTDGSDE
KL

ENSGT00720000108445_1_Linker_3_4 (663, 666)

CGA

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 828)

TTFEE--GDGGWHDVSVGRLRWAIQRAT----EPGAIALVLFPCPGAFLALQEGE
GQMVAPAKARTPLLGPSGLACSMEMSYHIQSGPQGFLAVSVVDHTTGMSHLAWHVRGH-G
SMAWGHVHILLGERARPFQVELLGLVDLQDQ--ADAAIDNVTFVQCDPNVVPPGATELSC
NFETGLCGWYQDQASDFQWVHSTGQGQGSDHTTGS---GYFLAANPSAPWSRGQRAQLIT
YDQEPAATPRCLTFWYRLAGPQIGTLNLKLQLEGAEETVLWTQRGTQGSLWHRGLATLPA
TGQKRYR--LAFEALRDGFVGDAALDDLLVTEGTCGAELS

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CSFEADTCGLTGSTQPTWLR
QSNSTG-T-IA--GPSADHTTGTAA--------GHYMVVSTSKGSLPMGHKATLTSAPYQ
PSAPAQCLAFWYQLSTGDP-GSLS--ILVEDSGV--LRKLFSMSTMEGDTWHRSQATVQA
DGDWKAIFEVVGAGGDHGYIALDDLHVSDGACP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

EPVS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFELDMCGWSSPVDEHLHSFAW
GWKSGVPLA-KYPGPEQDHTLGTKNGHYVHFDTRVLGAGGTTAQLESQHLPATA--DSCL
RFWYHMDIPEHLSDGELRVRLQSASGQRTAWTMAGHSSRGWQNGTVPVQSPSEFQIIFEI
TTRIWPMEGTVALDDIEYSTTGGCDSSPDTQGKAAEAG-CRLPLAQCNGGIILLVIIILA
-LAVASGWYLLKRRGQ---GSRMSA------ESSTPQGFDNITFRDDKVIIPPVQKESNP
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLFL------AGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCG
YHGASPT----------------LGAPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASG--
-----DVAELRVELIHGAETLTLWQSTGPW-GPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

NCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDENPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSWNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGTSNCSLVFYQYLRGSEAGCLQLFLQTLGPSAPRAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVSEVST--LQPLPP-
---GPRAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWRRVSAQESQGSSAAA-------AGHFLSLQRAW
GQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--SGSRELAWQALSS-S
AGIWKVDKVLLGARRRPFRLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTERDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPMECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRR
QANASG-HAAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLRSP-GTLR--VYLEERGK---HQVLSLSAHGGLAWRLGSVDVQA
ERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAA-P---GSLPAVVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEVTAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--------------WL---SLLAAGFPGWAWVPNHCKTPSEAVCNFVCDCRDCSDEAQCG
YQGASPTV----------------GAPFV

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAV-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEVSTAALRSPILHEAGPACELRLWYHTASG--
-----DVAELRLELTHSMETLTLWQSSGPW-GPGWQELVVATGRIRGNFQV---------
-------------------TFSATRNATHRGTVALDDLA

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWGCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 387)

RCLPGHH
HCQNKACVEPHQLCDGDDNCGDGSDE

ENSGT00720000108445_1_Linker_1_2 (387, 398)

DTPLCSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

NFETGLGLWDNL-----------
----------EGWARNHSTSSPERPAWPRRDHSWNSAQGSFLVSVAEP----SAPAILSS
PEFQASGPHNCSLVFYHYLHGSEAGSLQLLLQTGGPGAPQAP-----VLLRRRHGELGAM
WVRDRVDIQSKHPFRI--VLAGQTGP--GGIVGLDDLILSDHCKPVL-----VVSGPPP-
---GLWAPVPWP------QPSSLQPWDFCEPGHLSCGD-LCVPPEQLCDFQQQCMGGEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFETP-MAGGWEDASVGRLQWGRHLAQESRVPSTHA---SGAAAGYFLSVQRAW
GQLTAEARVLTPALGPSGPRCELHMAYYFQSHPQGFLALVVVE--DGNRELVWQVPSSSS
GG-WKVDTVLLGARHRPFWLEFVGLVDLDGPGHQGAGVDNLIMKD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTATSETDTEIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCGWHISHLTDSHWHRMESHGPGYDHTTGR---GYFMLLDPTDPPARGPGAQLLT
QPQVPAGSRECLSFWYHLHGPQIGTLRLVMRRDGEVDTHLWSRSGTHGNRWHEAWATLHH
QLDSGTKYQLLFEGLRNGYHGTMALDDVAVRPGPCWAPKRCSFEDSACGFSTRGQGLWMR
QTNATG-HTAW--GPRADHTTETAQ--------GHYMVVNTSPQALPRGHIASLTSEEHR
PLAQPACLTFWYHLSLQNP-GTLQ--VHVEEARR---RQVLSISAHGGFAWRLGSVDVQA
EQAWRVVFEAVAAGVEHSYIALDDLLLQDGPCPRPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWSHLPWPSLGGYSW
DWSSGDTPS-RYPQPSVDHTLGTEAGHFALFETGVLGPGGRAAWLRSQPLPPTV--VSCL
RFWYHMGFPEHFYKGELRVLLSSAQGQLVLWGAGGHLRHQWLESRLEVASTEEFQIVFEA
TLGGQPALGPIALDDIEYLAGQRCQLPAPSQGQTAATH----SMPAVVGGALLLL-VLLV
-LLALVGRHWLWKKG----DCAFGAK-----RAAAAPGFDNILFNADGVIL-PVSVTNDQ
--------------------

------------------------------------------------------------
---------------MC-LLIRAAQSLGKTWVPSHCRSPIEAVCNFVCDCGDCSDEAQCG
FHGASTTPS--------------MSIPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CSFEQDPCGWQDISTSGYSWLRDRAGAV-LD
GPGPRSDHTHGTDL--GWYMAVGTHNGKEASTATLRSPVMREAAPTCELRLWYHTASR--
-----DVAELRLELTHGVETLTLWQSSGPW-GPGWQELAVNTGRVQGDFKV---------
-------------------TFSATRNATHRGAVALDDVEFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPRPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

SCPLGQH
HCQNKACVEPHQLCDGEDNCGDRSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGLWNQL-----------
----------EGWTRNHSAGSMVSPAWPHRDHSRNSAYGFFLVSMAKP----GTTAVLFS
PEFQASVPYNCSLTFYYYLHGSEASCFQLFLQVQGLNTPPDP-----VLLRSHHGELGTA
WVRDRVDIQSAQPFRI--LLAGETGP--GGIVGLDDLIMSNYCKLVPDVST--VQS-CS-
---GSEALALCP------QTSMELPLEACEPGHLSCGE-LCVPPEQFCDFQQQCAEGEDE
HKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFESA-SAGGWEDTSIGRLQWQRVAAQN-RKLARDA---DRDVPGHFLSLQKAW
GQLRSEARARTPALGPSGPRCELHMTYRFHSHPQGFLALVVVE--NGFRELVWQAPSSSS
SKGWTVEKVLLGARHRPFQLEFVGLVDLDGPGQQWAEVDNVTMRDCNPTVTTESDREVSC
NFERDSCSWHTGHLTDAHWHRVKSHSSKYDHTTGQ---GFLMFLDPTDPPARGQGALLLT
RPQVPLVPKECLSFWYHLYGPQIGTLRLAMRKDGEEDTLLWSRSGTHGNRWHQAWVTLHH
QLEASTKYQLLFEGLRDGYRGTMALDDMAVRPGPCWAPKS

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSPGGLGLWKR
QSNASG-QAPW--GPWTDHTTETAQ--------GHYMVVDTSPDLLPKGHVASLTSEEHQ
PLTQPACLTFWYHLSLRNP-GTLR--VHLEASTR---RQELSISAHGGFAWRLGSVNVQA
GQAWRVVFEAVAAGVEHSYMALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

AQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAGPSLGAYSW
DWSRGATPS-RYPKPTVDHTLGTEAGHFAFFETSVLGPGGQKAWLRSEPLPATT--ASCL
HFWYFMGFPEHFYKGELRVLLSSAQGQLAVWAQGGHLRHQWIQVQIEVSNPEEFQIVFEA
TLGGQPALGPIALDDVEYLAGRHCQQPLPSQGER-A-P---MSVPIAVGGALLFF-MFLV
-LLGLGGRHWLQK-Q----PCPFQRS-----TDAATSGFDNILFNAVGT---PRSLNSPL
QPAVRGTEGAGPHPC-----

------------------------------------------------------------
--MPLHGH---LLPAV---VMLLAGSPGWAWVPNHCRTPREAVCNFVCDCRGCPDEAQCG
YHGTSPSL----------------GTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 341)

CDFERDSCGWRDISTAGYRWLRDRAGAS-PE
RPGLRADHTLGTDL--GWYVAVGTHRGRETATAALRSPVLHEAAPTCELRLWYHVASG--
-----DVAELRLELTHGVETLTLWQSAGPW-DPDWQELAVPTGRIRGAFRV---------
-------------------TFSATRNATHRGTVALDDVAF

ENSGT00720000108445_1_Linker_0_1 (341, 354)

WRCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 389)

HCPRGHH
RCQNEACVEPAQLCDGEDNCGDHSDEDA

ENSGT00720000108445_1_Linker_1_2 (389, 398)

APCRHYIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFEMGLGLWNHS-----------
----------EGWTRNHSAGGPRYPAWPRGDHTWNSAQGSFLASVAEP----STPAVLSS
PEFQASAPHNCSLVFYHYLHGSEAGCLQVFLQTASPAAPQTP-----VLLRRRHGELGAA
WVRDRVDIQSEHPFRI--LLAGQTGP--GGVVGLDDLILSNHCKPIP-----ELAGPPP-
---GCWAPGPWP------QPPSLRPRSFCEPGHFFCGD-LCVPPEQLCDFQQQCPGGEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 752)

DFESL-SGGGWEDASVGRLQWVRLPAPDRGMPSPDA---HG-AAGHFLAVQRAW
GQLAEEARALTPTLGPSGPRCELRLVYYLQS

ENSGT00720000108445_1_Linker_4_5 (752, 840)

HPR--------------------------
--------------------------------------------------------EVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERGACGWHTGHLTDAHWHRVESRGPRYDHTTGQ---GHFVLLDPVDPPARGPAAHLLT
QPRVPSAPQECLSFWFHLFGPQIGTLRLAMRREGEAETHLWSRSGTHGNCWHEAWATLHH
QPDSGAKYQLLFEGLRDGYHGSMALDDVTLRPGPCWAPRRCSFEDSACGFSVGGRGLWTR
QAN-----ASW--GPHADHTTETAQ--------GHYMVVDMSPQALPRGHAALLTSEEQR
PLVQPTCLTFWYHLSLRNP-GTLR--VHVEEAGR---QQVLSVSSRGGAAWRLGSVDLQA
GQAWRVVFEAVAAGVEHSYVALDDLLLQDGPCPLPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWNHVPRPGLGGYSW
DWSSGASPS-RYPQPPVDHTLGTEAGHFALFETSVLGPGGRAAGLISQPLPPTT--ASCL
RFWYHMGFPEHFYQGELRVLLSSAQGQLAVWGAGGRHRHQWLEGQVDVASAREFQIVFEA
TLGGQPALGPIALDDVEYLAGQRCQLSTPSQGDGAAAA----VVPAAVGGTLLLLV-LLM
-LLGVAGRRWLQK-G----GCPSWGK-----ADTVTPGFDNILFSADRVTL-PASVPHDQ
--------------------

------------------------------------------------------------
-------------------------------------NPRKTTCNFVCDFWDCFDESHCG
YHKESPAL----------------GAPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEEDSCGWQDISTSGYRWLRDRAGSA-FR
NPEPHTDHTFGTDL--GWYMAVGTHQGKEPATATLRSPVLHEAAPTCEIRLWYHGNIQ--
-----DVADLRMELTHNSETLILWQSIGQLGGSNWQELVVATGRIQGDFWV---------
-------------------TISATRNATHRGAMALDDVEFWN

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPSPQ---N

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCTRYQH
HCDNYACVELTELCDGEDNCGDASDEDKDS

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CIDYKVT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFENGLNHWTNT-----------
----------TGWVITRGSEASVASAEPVRDHSKNSASGSFLLSKAEQ----ENPAILVS
PEFYPSSTNNCLFTFYYYLHGSEDGNLQLFLQSLDPDSPQTE------LIRTRHGELGTA
WVRDRVDIYKKHPFRI--LLKGHTGP--GGVVGLDDLILNQHCKPANNASPPEASPLGP-
-----LAALPLHLQHLTKTGSRLQRDSFCEPGHFSCGD-FCLPPEQLCDFVPQCEGGVDE
QNCGKEWVLSNQA

PF00629 // ENSGT00720000108445_1_Domain_4 (674, 826)

LGGWEDASVG-LQWKRLNVQENSDPKTDA---TGNETGHFLSVKRAW
GQLTGMARARTPVLGPSGPSCTLKMAYYLQGQPEGFLALRVVE--DGVHELAWKIQGN-S
NDTWRWVTVPLGERERPFQLELLGKMDLKVPGTKGVGVDEITFVNCDPTVTTEKDTELSC
NFERDSCGWYPEHKTDALWQRASRPGPGYDHTTSQ---GHFMYLDPTMPPARGRGARLLT
ALQVPPTHNECLSFWYHLYGPQIGTLSLTLKRAGEPDRHLWARTGTHGNKWHQAWATLAH
PPDPITKYQLVFEAHRNGYHGNIAVDDITVRPGSCWAPRH

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CSFENSACGFLSSGQGTWQW
QGNATD-SVIR--GPRADHTTETSE--------GHYMMVDTSPSALPQGQRAVLTSEEYS
PLAQPGCFTFWYHLSLRNP-GTLH--VYVEEDKR---RRIFSVSAHGGFTWRLGSVDVQP
EKAWKVIFEAIGAGVEHTYIAVDDLHLKDGPCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

QPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESDMCSWSHTPWPGLGGYSW
DWSSGATPS-RYPQPPVDHTLGTNTGHFAFFDTSVLGPGGRAAWLRSEPLPPTPVGGSCL
QFWYHMGFPEHFYKGELKVLLLSSQGLLTLWGTGAYLRHQWLEGYVHVTSPVEFQIVFEA
TLGSQPVLGPIALDDIVYQTGQSCEPLVPNQEESSKPL----TIPVVMI--TFLVALILG
-LLAFGVWHRLKKG-----GYPFKREKE----NNTASGFDNVVFNSDHVTL-PSITSDQ-
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLFL------AGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCG
YHGASPT----------------LGAPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWQDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASG--
-----DVAELRVELIHGAETLTLWQSTGPW-GPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

NCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDENPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSWNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGTSNCSLVFYQYLRGSEAGCLQLFLQTLGPSTPRAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVSEVST--LQPLPP-
---GPRAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWRRVSAQESQGSSAAA-------AGHFLSLQRAW
GQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--SGSRELAWQALSS-S
AGIWKVDKVLLGARRRPFRLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTERDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPMECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRR
QANASG-HAAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLRSP-GTLR--VYLEERGK---HQVLSLSAHGGLAWRLGSVDVQA
ERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAA-P---GSLPAVVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
------------------------------------------------------------
----------------YSRPASTLGSTFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFERDPCGWQDISTSGYSWLRDRAGAA-PR
GAGIRSDHTLGTDL--GWYMAVGVHRGKEPATAVLRTPVLREAAPTCELKLWFHAVAG--
-----DVAELRLELTHSTETLTLWQSEGPW-GPGWQELVVVTGRVRGDFQV---------
-------------------TFAAVRNATHRGAVALDDVEFRDCGLPTPQ---ASCPLGHH
RCGNQACVEP-QLCDAEDNCGDSDEXXXXXXXXXXXXXXXXXXXXXXXX-----------
----------XXXXXXXXXXXXXXXX----XX-XX-XXXXXXXXXXXX----XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXX
XXXXXXXXXXXXXXXI--LLAAHTGP--GGVVGLDDLILSESCKPAAETTPPAT---P--
-----------S------PPWGPQPRGLCEAGQLACED-LCIPPEQLCDFEQQCPEGEDE
RGCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 753)

TDFESP-KMGGWEDTSVGRLQWQWLMAQESPGPGVDA-------SGHFLSLQTAW
GQLRAAARLLSPTLGPSGPHCEFQLAYYFQSHP---------------------------
-------------------------------------------------------QEISC
NFERDACGWYPGHLADAHWQRVQSRGPGYDHTTGQ---GFFMLLDPADPPARGQGAHLLT
GLQTPTAPVQCLSFWYHLYGPQIGTLRLALRRAGEEDTELWSRSGTHGNRWXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXX
XXXXXX-XXXX--XXXXXXXXXXXXXX

PF00629 // ENSGT00720000108445_1_Domain_6 (1048, 1174)

XXXXXXXHYMLVDTRPGALARGQVATLTSGEHR
ALTQTGCLTFWYQLSPRSP--SLR--VYVEEGGR---QQVFSVSAHGGFAWRLGSVDVQA
KWAWRVVFEAMATGEKHSYVALDDLLLQDGPCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

QPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFESGLCGWSHLAWPSLGRPSW
DWSSAATPS-RYPQPRTDHTLGTAEGHFAFFETGVLGAGGRTAWLRSEPLPPTQ--AACF
RFWYYLGLPEHFYKGELRVLLSSSQGQLAVWSQGGPAQ-HWQEAQLNVTSTQEFQMVFEV
TADGQPALGPIAVDDIQYLEGEPCQQPALNQGNRATRA----LVPAVVGGILFL--LLLV
-LLGLGGLHWLCKKG----ICPFGGHAEATGSAAAASNFDNILFNE--------------
--------------------

------------------------------------------------------------
--MSLPGHLLPSLVLLV------AGFPGWAWVPNHCRSPSEAECNFVCDCSDCSDETQCG
HHGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEHDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPRSDHTLGTDL--GWYLAVGTHQGKEASTAVLRSPVLREAAPTCELRLWYHSSSG--
-----DAAELRLQLTHGAETLTLWRSSGPW-GPGWQELAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWGCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKACIESHELCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 582)

DFETGLGPWNHS-----------
----------EGWARNHSAGSPEHPAWPQRDHSRNSAKGAFLVSLAEP----GNPAVLFS
PKFQASGPDNCSLVFYRFLHGSEASCLQLFLQTLQPGVPPAT-----VLLRRHCGELGAA
WIRDRVDIQSAHPFQI--LLTGQTGP--GGVMALDDLILTD

ENSGT00720000108445_1_Linker_2_4 (582, 659)

GCKPVPEPAA--PQVLPP-
---APQAPAPET------PPSSLRPQNFCDPGHLSCGD-LCVPPEQLCDFQQQCAGAE

PF00629 // ENSGT00720000108445_1_Domain_4 (659, 826)

DE
QDCGTTDFESP-TAGGWEDASVGPLQWQLSAQE--------------AAVGRFLSLQRAW
GQLRPEARALSPALGPSGPGCELHLAYYFQSQPRGFLALVVEA--GSSRELVWQAPGS-T
AGGWKVDKTLLGARRRPFRLELMGLVDLDGPGQQGAGVDNVTLRNCSPMATTERDREVSC
NFERDTCSWYPGHLTDAHWHRVQTHGPGYDHTTGQ---GHFMLLDPTDPPARGCGAHLLS
RPQVPAAPVECLSFWYQLHGPQIGTLRLAMRREGEEDTLLWSRSGTHGNRWQEAWATLHH
QPSSRTRYQLLFEGLRDGYHGSMALDDVAVRPGPCWAPRR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSACGFSTGGQGLWKR
QTNASG-HAAW--GPQTDHTTETAR--------GHYMMVDLSPNALPRGQVASLTSEEYR
PLAQPTCLTFWYHLSLRSP-GTLR--VHVEEGGR---HPVLSIRARGGAAWRLGSVDVQA
RWAWRVVFEAVAAGVEASYVALDDLFLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PPPGF

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGRYSW
DWSGGATPS-RYPHPAADHTLGTEAGHFAFFETGVLGPGGQAAWLRSEPLPATQ--ASCL
RFWYHMGFPEHFYKGELRVLLASAQGQLAVWGQGGHRRHQWLEAQVEVASAEEFQVVFEA
TLSGQPALGPIALDDIEYLAGQRCQQPAPSQGHMAI-P---VAVPATVGGALLLL-MLLM
-LLGLGGRRWLRKRG----GCPFWSD-----REAATPSFDNVLFNADCVTL-PESVTSDP
Q-------------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAACNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGPW-DPGWQELAVTTGRIWGDFRV---------
-------------------TFSATRNATHRGAVALDDLA

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PAFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPVPQP------LPPSSRLQDSCKQGHFACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTKRDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYYLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHHCSFEDSDCGFSSGGRGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYS
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGRK---HQVLSLSAHGGLAWRLGSVDVQA
EQAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTKAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELRVLLRSTQGQLAVWGTGGHRRHQWLEAQVEVASTKEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--MRLLGYLLPSLLLLI------AGALGWAWVPSHCRPPSEAVCNFLCDCSSCSDEEQCG
HHGASPA----------------LGTPFS

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWQDISTSGYSWIRDRAGAT-LE
GPGPHSDHTLGTDL--GWHMAVGTHRGKEVSTAVLRSPTLREAAPTCELRLWYHVASG--
-----DVAELSLQLTHNTETLTLWWSSGPW-GPGWQELAVTIGRIRGDFRV---------
-------------------TFSATRNATHRGTVGLDDIE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWGCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPPGHH
HCQNKACIEPHQLCDGEDSCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHMVT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

NFETGLGPWNHL-----------
----------EGWVRNHSNASPEHPAWPHRDHSQNSVRGSFLVSLAEP----SRPAALFS
PKLQASGPYNCSLVFYHYLHGSEASCLRLFLQTLLPSSSPAP-----VLLQSRCGELGAA
WVRDRVDIQSAHPFQI--LLAAQTGP--GGVVGLDDLILSNHCQLVPELAA--LQMLPP-
---TPWAPAPES------PPSGPWFQNVCSPGHLSCGD-LCVPPEQLCDFQQQCTGAEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 827)

DFESP-TAGGWEDASVGRLQWQLSAQR--------------AATGHFLSLQKAW
GQLRPEARVLSPALGPSGPRCELHLAYYFLSQPRGFLALVVVD--GSSRELVWQAPSS-S
TGGWKVDKTLLGARRRPFRLEFIGLLDLDGPGQQGAGVDNVTLRNC

ENSGT00720000108445_1_Linker_4_5 (827, 840)

SPTETTERDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYTGHFTDAHWHRVQSHGPGYDHTTGR---GHFMLLDPTEPPARDHGAYLLS
QPQVPVAPIECLSFWYHLYGPQIGTLRLLLRREGEEDTPLWSRSGTHGNRWHEAWATLHH
QPHFHTQYQLLFEGLRDGYHGTMALDDVALRPDPCWAPKHCSFEDSGCGFFTGDQGLWKC
QTNASG-QAAW--GPPTDHTTETAQ--------GHYMVVDMSPNALPQGHVATLTSEEYR
PLAQSACLTFWYHLSPRNP-GTLR--VHMEQSGR---RQVLSISAQGGAVWRLGSVGIQA
GQAWRVVFEAVAAGVQPSYVALDDLFLQDGACPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFETGLCGWSHLAWPGLSGYSW
DWSSGTTPS-RYPHPSVDHTLGTEAGHFAFFETGVLGPGGQVAWLRSEPLPATQ--ASCL
RFWYHMGFPEHFYKGELRVLLASTQGQLAVWGQGGHRRHQWLEAQVEVASTEEFQIVFEA
TLSGQPALGPIALDDVEYQAGHHCQVPTPSQGHAAM-P---GSVPAAVSGALLLF-MLLV
-LLGLGGWLWLQKTG----GCPFWSN-----REPVTSGFDNILFNADHVTL-PASVTNDP
--------------------

------------------------------------------------------------
--MQLPTDLLPALVLFT-GKLSAAQSLGRAWVPGPCRSPTEAQCNFLCDCGDCSDETQCG
YNGALPG----------------LGTSFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWQDISTSGYSWVRDRAGAQ-PE
RPVAHTDHTRGTDL--GWYMSVGAHRGMEASTAALRSPVLREAGPACELRLWYHAASG--
-----DVAGLQLELTHSAEALTLWQSSGPW-GPGWQELAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

TCPLSQH
HCTNAACIEPHQLCDGEDNCGDGSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHTGT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGLWNHS-----------
----------EGPAWNLSTGGPKGSAWPHRDHSRNSAQGSFLVSTAKP----GNPAILLS
PQLQASGSRNCSLIFYHYLHGSKDARLELLLQMQGPGAPQAP-----ALLRQRHGELGAA
WVRDRVDIWSAHPFRI--LLAGETGP--GGIVGLDDLILSDHCKIIPGDVT--WAPLSP-
---VPWPKAPHP------QQST--LQGSCEAGQLACGD-LCVPPEQLCDFQPHCAQGEDE
HECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFEAA-AAGGWEDASVGRLQWGRQAAQESRGM-------GRAAAGYFLSLQRAW
GQLRAEARALTPILGPSGPHCELHMAYYFHSHPRGFLALAVVD--SSSRELVWQAPRS-S
SRDWRVDKVLLGAHHRPFRLELVALVDLEGPGQEGAGVDNVTMRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTEKDREVT

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFEWDTCGWHLGHLTDVHWRRVESHSSGYDHTTGQ---GFFMLLDPAEPPTRGYHAHLLT
GPLVPAAPEQCLSFWFQLHGPQTGTLRLAMRRDSGEDVQLWSASGTHGNRWHQAWATLHH
QLGPSSKYQLLFQGLRDGYDGIMALDDVTVRPGTCPAPWRCSFEDSACSFSSGGQGLWRR
QTSTSG-PAIP--GPWADHTTETAQ--------GHYMVVDTSPDMLPRGHVASLTSEEHW
PLLHPACLTFWYHLSLRSP-GTLK--VRVEEGGW---HQTLSISEHGGLAWHLGSMDVQA
KQAWRVVFEAVAAGVENSYIALDDILLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGGYSW
DWSSGATPS-RYPRPPVDHTLGTAAGHFAFFETSVLGPGGRAAWLRSEPLLATE--ASCL
RFWYHMGFPEHFYKGELRVLLVSAAGQLAVWVGGGRLRHQWLEAQVEVTSTQEFQIVFEA
TLGGQPVQGPIALDDIEYLPGQRCQWPALSPGEHWA---VNVSVAAAVSGALLFL-VLLV
-LLILAGWHWLQKG----RGWPFRRS-----TDSAAPGFDNILFNADQVTL-PAAVTSDP
--------------------

------------------------------------------------------------
--MPLPGHLLPILVLLL------AGSPGWAWVPNHCRIPSQAMCNFVCDCGDCLDEAQCG
YHGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFELDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPRSDHTLGTDL--GWYMAVGTHRGKETATAALRSPTLREAAPSCKLRLWYHTASG--
-----DVAELRLELTHGAETLTLWQSTGPW-GPGWQELAVTAGRIQGDFRV---------
-------------------TFSATRNATHRGTVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKACVELQQLCDGEDNCGDLSDEDPRT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGQHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETDLGLWSRS-----------
----------EGWARNHSAGSPDHPAWPCRDHSRNSAQGSFLVSVAEP----GNLAALSS
PELQASGASSCSLVFYYYLHGSEAGCLQLFLQTLGSSTPQAP-----VLLRRRRGELGTT
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSEHCRPVLEVST--PQPLPP-
---GPRVPVLGS------LPPSSRLQDFCQQGHLACGD-LCVPPEQLCDFEQQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWQRLSAQESQGAGAAA-------TGHFLSLQRAW
GQLGTEARVLTPMLGPSGPSCELHLAYHLQSQPRGFLALVVVD--SSSRELAWQALSS-S
AGGWKVDKVLLGARRRPFRLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPMVITKRDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDAHWRRVESHGPEHDHTTGQ---GYFMLLDPTDPLARGHSAHLLS
RPQVPAVSTECLSFWYYLYGPQIGTLRLAMRREGE-DTHLWSRSGTHGNRWHQAWATLSH
QPGSQAPYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPDYCSFEDSDCGFSPGGQSLWRR
QANASG-HTAW--GPPADHTTETAQ--------GHYMVVDTSPDALPWGQTASLTSKEHR
PLAQSACLTFWYHGSLLSP-GALQ--VHLEEGRR---HQVLSLSAHEGLAWQLGSVEVQA
EQAWRVVFEAVGTGVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHRAWPGLGGYSW
DWGGGAAPS-RYLQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELRVLLRSAQGQLAVWGTGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGSQPALGPIGLDDVEYLAGQHCQQPAPSLGDTAT-P---VSVPAVVGGALLFL-MLLV
-LLGLGGRRWLQKRR----SCPFQSN-----TEATAPGFDNILFNAASVTS-DP------
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPSQAACNFVCDCRDCSDEAQCG
YRGASLA----------------LGTPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGSW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHGGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSWNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCKQGHFACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGAHRRPFQLEFVGLVDLDGPDQQGAGVDNVTLKDCSPTVTTERDREVSC
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYYLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHH

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSSGGRGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLISKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWRLGSVDVQA
EQAWRVVFEAVAAGVAHSYVALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTKAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELRVLLCSAQGQLAVWGTGGHWRHQWLEAQVEVASTKEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSKP
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLFL------AGSSGWAWVPNHCRSPGQAVCNFLCDCRDCSDEAQCG
YHGAWPT----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASG--
-----DVAELRLELTHGAETLTLWQSTGPW-GPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCENKVCVEPQQLCDAEDNCGDQSDENPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSQNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PKFQASGTSNCSLVFYHYLHGSEAGCLQLFLQTLGPSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLTGQTGP--GGVVGLDDLILSDHCRPVSEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCERGHLACGD-LCVPPEQLCDFEEQCAAGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESP-EAGGWEDASVGRLQWRRLSAQEGQGSSAAA-------AGHFLSLQRAW
GQLSAEARVLTPLLGPSGPNCELHLAYYLQSQPRGFLALVVVD--NGNRELAWQALSS-S
AGSWKVDKVLLGARRRRFRLEFVSLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTERDREIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESHGPDHDHTTDQ---GHFVLLDPTDPLAWGHSAHLFS
RPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGE-EIHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNDCSFEDSDCGFSPGGQGLWRR
QANASG-HAAW--GPPTDHTTETAR--------GHYMLVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLHSP-GTLR--VYLEESGR---HQVLSLSAHGGLAWRLGSVDVQA
KQAWRVVFEAVAADVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGRYSW
DWGGGATPS-RYPQPRVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSELLPATP--ASCL
RFWYHMDFPEHFYKGELKVLLHSAQGQLAVWGTGGHRRHQWLEAQVEVASTKEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQQPAPSPGDTAA-P---VSVPAAVGSTLLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPSFDNILFNA--------------
--------------------

------------------------------------------------------------
--MRLPTRLLSVLVLLM-GELAAVQSLGRAWVSNPCASPVEAQCDFLCDCRDCSDETQCG
YNVASPS----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDPCGWQDISTSGYNWVRDRAGAQ-PE
GPVAHTDHTRGTDL--GWYMAVGTHHGTQASIAALRSPVIREAGPACELHLWCHVTSG--
-----DVAELQLELTHRAETLTLWQSSGPW-RPGWQELVVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWNCGLPAPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

TCPLGHH
HCQNAACIESHQLCDGEDNCGDGSDEDLLS

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSQHMIT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGLWTYS-----------
----------EGSAWNHSTGGPKGSAWPHRDHSRNSPQGSFLVSMAMP----GNPAMLLS
PQLQASGSHNCSLIFYHYLHGSEDGRLELLLQTQSPGTSQAP-----VLLRQRHGELGTS
WVRDRVDIRSTHPFWI--LLTGDTGP--GGVVGLDDLILSDHCTVTP-------------
---GSVPAAPRP------QQSS--LQGPCQPGQLACRD-LCVPPEQLCDFQPQCAQGEDE
HECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESA-AARGWEDVSIGQLQWVRLAAQESGGP-------SKAAAGHFLSVQRAW
GQLRAEARALTPVLGPSGPHCELHMAYHFHSQPQGFLALAVVE--SGSRELVWQAPGS-S
SRDWTVDKVLLGAHHRPFRLELVALVDLDGPGQQGAGVDNMTMRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTEKDREVT

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFEWDACGWHLGHLTDVHWHRVESHSSGHDHTTGQ---GFFMLLDPAEPRSHGRQAHLLT
EPQVPVAREQCLSFWFHLHGPQIGTLRLAMWRDGEEEVPLWSGSGTHGNRWHQAWATLHH
QLEPSTKYQLLFQGLRDGYHGIMALDDVTMQPGACPAPQRCSFEDSTCSFSSGGQGLWRR
QASALG-HAAS--GPWTDHTTETAQ--------GHYMVVDTSPDALPRGHVASLTSEEHW
PLPQPACLTFWYHLSQHNP-GTLQ--VRVEEGDH---HQTLSISEHGGLVWRLGSMAVQA
KQAWRVVFEAVAAGVEHSYMAVDDVLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWSHLAWPGLGGYSW
DWSSGATPS-PYLRPTVDHTLGTEAGHFAFFETGVLGDGSRAAWLRSEPLPATE--ASCL
RFWYHMGFPEHFYKGELQVLLVSVRGQLVVWAEGGRLRHQWLKAQVEVASAEEFQVVFEA
TLGGQPVQGPIALDDIEYLAGQHCQRPTVSPGVW---A-AHVSVLAAVGGALVFL-TLLV
-LLGFAGRHWLHKKG--GWGWPFQRD-----KDSAAHSFDNILFNADQVTL-PAAVTSNP
--------------------

------------------------------------------------------------
--MPLPSHLLPTLVLLL------ARSPGWAWVPSHCRSPGQAVCNFVCDCRDCSDEAQCG
YRGASPA----------------LDTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCQLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGPW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDIQFGD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSDHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPAPQP------LSPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAV-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRDCSPTVTTERDREVSC
NFERDTCSWYPGHLSDTHWRWVESHGPDHDHTTGQ---GHFVLLDPTDPMAWGHSAHLLS
RPQVPAVPTECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHH

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSSGGQGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPEALPRGHTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWHLGSVDVQA
ERAWRVVFEAVAAGVAHSYVALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--VSCL
RFWYHMGFPEHFYKGELRVLLRSARGQLAVWSTGGHRRHQWLEAQVEVASTNEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTVVGSALLLL-MLLV
-LLGLGGRRWLK-RG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

PF00629 // ENSGT00720000108445_1_Domain_0 (200, 343)

MAVGTHQGKEASTAVLRSPTLREAASSCKLRLWYHAASG--
-----DVAELRLELTHGPETLTLWQSTGPW-GPGWQELAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDLEFWD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDENPHT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGTSKCSLVFYHYLHGSEAGCLQLFLQTLGPGAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSTHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVLEVST--LQPLPP-
---GPWAPAPQP------LLPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 760)

DFESP-EAGGWEDASVGRLQWRRLSAQESQGSSAAA---AGEAQGHFLSLQRAW
GQLSAEARVLTPLLGPSGPRCELHLAYYLQSQLRGFLAL

ENSGT00720000108445_1_Linker_4_5 (760, 880)

V--------------------
------------------------------------------------------------
---------------------------------------

PF00629 // ENSGT00720000108445_1_Domain_5 (880, 996)

HFVLLDPTDPLAWGHSAHLLS
RPQVPTAPTECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRR
QASASG-HAAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEHR
PLAQPACLTFWYHGSLRSP-GTLR--VYLEERGR---HQVLNLSAHGGLAWRLGSVDVQA
ERAWRVVFEAVATDVAHSYVALDDLLLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEA
TLGSQPALGPIALDDVEYLAGQRCQQPAPSPGDTAT-P---VSVPAAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----REATAPGFDNILFNVDGVSL-PASVTSDP
--------------------

------------------------------------------------------------
--MSLPGHLLPV---L---VLLLARSPGWAWGPSRCRPPREAVCNFVCDCRGCPDEAQCX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXXXXXXXX---
----XXXXXXXX-X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
-----X

PF00629 // ENSGT00720000108445_1_Domain_0 (247, 345)

VAELRLELTHGVETLTLWRSSGPW-VPGWQELVVPTGRIQGDFRV---------
-------------------TFSATRNATRRGAVALDDVAFWSCG

ENSGT00720000108445_1_Linker_0_1 (345, 353)

LPTPQ---

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

AHCPLGHH
HCQNKACVEPHQLCDGEDNCGDGSDEDTPT

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CNHHTA

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 585)

TDFERGLGLWNRS-----------
----------EGWARNHSAGGPQHPAWPHRDHSRNSAQGSFLVAVAEP----SAPAILSS
PEFQASAPEKCSLTFYHYLHGSQAGCLQVFLQTRSAGAPHAA-----VLLRRRHRELGAA
WVRDRVDIQSKHPFRI--LLAGQTGP--GGVVGLDDLILSDHCKPVP-----EVAGPPP-
---GLWAPGPRS------QLSSLQPWNFCEPGHLLCGE-LCVPPEQLCDFQQQCPGGEDE
QECGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 753)

TDFESP-SAGGWEDASVGRLQWVRLPAQDSGSPGMDA---SG-AAGHFLSVQRAW
GQLAEQARVLTPTLGPSGPRCELHMAYYFQSH

ENSGT00720000108445_1_Linker_4_5 (753, 840)

P---------------------------
-------------------------------------------------------QEIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 997)

C
NFERDTCGWHTGHLTDAHWHRVESRGPGYDHTTGQ---GHFMLLDPTEPPAQGPGAHLLT
WPQSPAAAQECLSFWYHLYGPQIGTLRLAMRREGERERHLWSRSGTHGNRWHEAWATLHH
PQDSSAKYQLLFEGLRDGYHGTMALDDMTVRPGPCWAPKRCSFEDSACGFSTGGRGLWTR
QTNATG-QAAR--GPPADHTTETAQ--------GHYMVVDMSPQ-QPRGHVASLISEEHR
PLAQAACLTFWYHLSLRNP-GTLR--VHVEEAER---RQVLSIGTDGGFAWRLGSVDLQA
ERAWRVVFEAVAAGVERSYIALDDLLLQDGPCPRPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFEAGLCGWNHLPWPGLGGYSW
DWSSGAAPS-RYPQPPVDHTLGTEAGHFALFETGVLGPGGRAAWLRSQPLPATE--ASCL
RFWYHMGFPEHFYKGELRVLLSSARGQLAVWGAGGRLRHQWLEGQVEVASAEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQRCQLPTPSQGDTAVAT----SVPAVVGGTLLLL-MLLV
-LLGLAGRRWLQNRG----GCPFWGE-----TDTVAPSFDNILFNAGHVTL-PASVTNDQ
--------------------

------------------------------------------------------------
--MCLPSCLLSIWVLFM-A----AQSLGKTWVPDHCRSPTEATCNFVCDCGDCSDEAQCG
FHGASTTP----------------NTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CNFEQDPCGWQDISTSGYRWLRDRAGAG-LD
SSGPHSDHTRGTDL--GWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHTDSR--
-----DVAELRLDLTHGMETLTLWQSSGPW-GPGWQELAVNTGRIQGDFKV---------
-------------------TFSATRNATHRGAVALDDME

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPIPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

RCPLGHH
HCQNKACVEPHQLCDGEDNCGDSSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWTQL-----------
----------EGWTRNFSAGSMVSPAWPHRDHSRNSAYGFFLVSVAKP----GTTAVLYS
PEFQGSVSYNCSFTFYYYLHGSEANQFQLFVQAQGLNTTQPP-----VLLRSRHGELGTA
WVRDRVNIQSAHPFRI--LLAGETGP--GGFVGLDDLIMSNHCILVPGMST--LQSSLS-
---GPVPLALYP------QTSIK---RTCEPGHLSCDE-LCVPPEQLCDFQQHCAEGEDE
EKCGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESA-SAGGWEDISIGKLQWQRAEAQESGKPARDT---NRNAPGHFLSLRKAW
GQLRSEARALTPALGPSGPHCELHMTYYFHSHPQGFLALAVVE--NGFRELLWQAPSS-S
SGGWTLQKILLGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CNPMVTTESDQEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDSCSWHTGHLTDAHWHRVKSHGSQYDHTTGQ---GFFMFLDPMDPPARGQGALLLT
RPQVPVVPKECLSFWYHLHGPQIGTLCLAMRREGEEDTLLWSRSGTHGNRWHQAWVTLHH
QLQPSTKYQLLFEGLRDGYHGTMGLDDMAVRPGPCWAAKRCSFEDSDCGFSPGGWGLWTR
QNNASG-LGPW--GPWIDHTTGTAQ--------GHYMVVDTSPNLLPKGHVASLTSEEHP
PLSRPACLTFWYHLSFHNP-GTLR--VFVEESTR---RQELSISGHGGFAWRLGSVNVQA
EQAWKVVFEAMASGVEHSYMALDDISLQDGPCAQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLPWPGLGGYSW
DWSSGATPS-RYPRPSVDHTVGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATA--VSCL
HFWYYMGFPAHFYKGELRVLLSSTQGQLAVWHRGGHLRDQWLQVQIEVSSSEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCKQPTPSQGGVAA-P---VSVPVAVGGALLLF---LL
-LLGLGGWHWLQK-Q----HLPCQ-S-----TDAAASGFDNILFNADQVTL-PESITSNP
--------------------

------------------------------------------------------------
--MWLPAYLLPALVLLM-GEWAAAQALGRAWASSPCQSPVEAQCDFLCNCRDCSDETQCG
YRVASPS----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWQDISTSGYSWVRDRAGAQ-PE
GPVAHADHTRGTDL--GWYMAVGTHLGTEASIAALRSPVLREAGPACELRLWYQAASG--
-----DVAELQLELTHRAETLTLWRSSGPW-RPGWQALAVTTGRIQGDFRV---------
-------------------TFSATRNATHRGAVALDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

TCPVGHH
HCQNAACIESHQLCDREDNCGDGSDEDLLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGLWTHS-----------
----------EGPAWNHSTGSPKGSAWPSRDHSRNSAQGSFLVSTAKP----GSPAVLLS
PQLQASGSHNCSLIFYHYLHGSEDGRLQLLLHTQGPRASQAP-----VLLRQRQGELGAA
WVRDQVDVRSAQPFWI--LLTGETGP--GGVVGLDDLILSDHCTHSAP---------QG-
---RSWPKAPWP------QQSS--LQGSCQPGQLACGD-LCVPLEQLCDFQPQCAQGEDD
SVLGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESA-TAGGWEDASVGRLQWVRLAAQERGGP-------GRTAAGHFLSVQRAW
GQLRAEARALTPVLGPSGPHCELHMAYYFHSRPRGFLALAVVD--SGSRELVWQAPGG-S
SWDWTLDKVLLGAHRRPFQLELVALLDLDGPGQQGAGVDNVTMRNCSPTVTTEKDREVTC
NFERDACGWHLSHLTDVHWHRVESHSSGYDHTTGQ---GFFMLLDPTNPLSRDHHAHLLT
EPQVPAALDQCLGFWFLLHGPQIGTLRLAMRRNKEEEVQLWSGSGTHGNRWHQAWATLNH
QLEPSTKYQLLFQGLRDGYHGIMALDDVTLQPGTCPAPQR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEESACSFSSGGQGLWRR
QASAWG-HAAR--GPWTDHTTETAQ--------GHYMVVDTSPDVLPRGHMASLTSEEHW
ALPRPACLTFWYHLSLQSP-GTLQ--VRVEEGGR---HQTLSISEHGALAWRLGSMDVHA
EQAWRVVFEAVAAGVEHSYIALDDVFLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGGYSW
DWSSGAAPS-PYARPPVDHTLGTEAGHFAFFETGVLGAGGRAAWLRSEPLPATA--ASCL
RFWYLMGFPEHFYKGELHVLLASSRGRLEVWAAGGRLRHQWLEAQVEVASDDEFQVVFEA
TLGGQPVQGPIALDDIEYLAGQHCQWPAPSPGEHWDTA-AHVSVLAAVSGALVFL-VLLV
-LLGLAGRHWLQKSG--GWGWPFQRD-----KDLAAPGFDNILFSADQVTL-PAAVTSDP
--------------------

------------------------------------------------------------
--MPLPGHLLP--ALV---LLLAAGSPGRAWTPSTCRAPGEATCNFVCDCPGCSDETQCG
YHAASPAL----------------GVPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEQDSCGWRDISTSGYSWLRDRAGAT-LE
ALGPRSDHTLGTDLGPGWYMVVGIHRGKEAAGATLRSPVLWNAAPTCELRLWYHVAAG--
-----AVAELRLELTHRAETLTLWQSSGPW-GTGWQELVVTTGRIQDDFRV---------
-------------------TFFATRNATHRGSVALDDLVFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPAPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

HCPLGHH
HCQNLACVAPHQLCDGEDNCGDRSDEDAYS

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CRHHIAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFEMGLGLWNHL-----------
----------EGWARNHSTGA-WHPAWPHRDHSQNSAQGFFLVSVAEP----SSPAVLSS
PIFQASGAHNCSLVFYYYLHGSEHGSLQLFLQMENPGSPQVS-----ILLRRRCGELGAA
WVRDRVDIQSEHPFRI--LLTGHTGP--GGVLSLDDLILSEHCQ--PVPAPTELSSPPR-
---GLWALALQP------QPSSLPPQDFCEPGHLSCGE-LCIPPEQHCDFQQQCEGGEDE
QECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 827)

DFEAP-AAGGWEDASVGRLQWRRLQAQESGGPGTDA---GGVAAGHVLSLQRAW
GQLAAEARVLTPALGPSGPRCELRVAYYFHGHPQGFLALVVVE--GDSRELVWQAPSG-D
RG-WKVDTILLGARRRPFRLELVGLVDLDGPGQQGAGVDDVTLKDC

ENSGT00720000108445_1_Linker_4_5 (827, 840)

SPAAA-MQDSEIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCGWHTGHLTDAHWRRVQSRGHGYDHTTGQ---GYFLLLDPTDPPARGPGAHLLT
QPQAPSGPQECLSFWYHLHGPQIGTLRLAVRREGEAEVLLWSRTSTQGNRWHKAWTTLHH
QLGSGTKYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPRQCSFEDSACGFSSGGQGLWTR
QANATG-LASR--GPHTDHTTETAQ--------GHYMVVDMSPQALPRGQVASLTSEVHQ
PLAQPACLTFWYHLSLRNP-GTLQ--VHVEEAQR---YQVLSISARGGFAWRLGSVDVQA
ERAWRVVFEAVAAGTEHSYIALDDLLLQDGPCPQPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1344)

CDFEAGLCGWSHMPWPGLGSYSW
DWSSGATPS-RYPQPPVDHTLGTEAGHFVLFETGVLGPGGRAAWLRSQPLPATE--ASCL
RFWYHVGFPEHFYKGELRVLLSSVRGQLAVWGTSGHLRHQWLEGQVEVASAEEFQIVFEA
TLSGQPALGPIALDDVEYLAEQHCWLPAPTQGDTLLAA----SVPTMVGSALLIL-VLLV
-LLGLVGRCWLQKKG----GCPSQGE-----MAAEASGFDNIVFNADCVTL-PASLTDNQ
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAACNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAT-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGSW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHGGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPSPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCHNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGHHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSWSHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCKQGHFACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLESQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGAHRRPFQLEFVGLVDLDGPDQQGAGVDNVTLKDCSPTVTTERDREVSC
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYYLHGPQIGTLRLAMRREGE-ETHLWSQSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHH

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSLGGRGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLISKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWRLGSVDVQA
EQAWRVVFEAVAAGVAHSYVALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

PRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTKAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHVGFPEHFYKGELRVLLRSAQGQLAVWGTGGHRRHQWLEAQVEVASTKEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSEP
--------------------

------------------------------------------------------------
------PPLAP--HLG---APGAAGPPGRAWVPNDCRAPSEAACNFVCDCPDCSDEAQCG
ELGPGGVTTGSRPETPAAGGTSAPQATGGCETGQDLWGRAQTTLSAQTSVRPRRGP----
----R--------AGPSQQA-AGS-SGAQA---A--------PGP-------PAPPLT--
-----DV

PF00629 // ENSGT00720000108445_1_Domain_0 (248, 340)

AELRLELTHRAETLTLWQSSGPW-GPGWQELVVATGRIRGDFWV---------
-------------------TFSATRNATHRGTVALDDVV

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FRGCGLPSPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 389)

RCPLGYH
HCGNMACVEPHQLCDGEDNCGDGSDEDT

ENSGT00720000108445_1_Linker_1_2 (389, 398)

PACRH-TAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNHS-----------
----------EGWARNHSAG-PRPPAWPRRDHSRNSAQGSFLVSVAEP----SAPAVLSS
PEFQASGPHNCSLIFYHYLHGSEGGCLQLFLQIQSPGSPQGP-----VLLRRRHGELGAA
WVRDRVDIQSEHPFRI--LLTGHTGP--GGVVSLDDLILSDH

ENSGT00720000108445_1_Linker_2_4 (583, 662)

CQP--------ASGSPP-
---GLWAAAPWR------QPSSLRPRDFCEPGHLSCGD-LCVPPEQLCDFQQQCEGGEDE
Q

PF00629 // ENSGT00720000108445_1_Domain_4 (662, 826)

DCGTTDFEPL-TGGGWEDASVGRLQWGRLLAQESRGPG----------AGHFLALQRAW
GQFAAEARVLTPPLGPSGPRCELHMAYYFQSHPQGFLALVVVE--DSNRELVWQAPGS-S
QG-WRMDRVFLGARRRPFRLEFVGLVDLDGPGRQGAGVDDVTLKD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPVTATEKDSEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCGWYIGHLTDAHWRRIQSHGPGYDHTTGR---GYFLLLDPTDPPARGPGAHLLT
QPQVPTAPQECLSFWYHLHGPQIGTLRLVLRREGEADTLLWSRTGTHGNHWHEAWATLHH
QPGSGTKYQLLFEGSRDGYHGTMGLDDVALRPGPCWAPRRCSFEDSACGFSSGGQGLWTR
QPNATG-HAAW--G--------------------HYMVVDTSPQALPPGHVASLTSEEHQ
PLARPACLTFWYHLSLRNP-GALQ--VHVGEAER---QQVLSISAHGGSAWRLGSVDVQA
ERAWRVVFEAVATGVEHSYIALDDLLLQDGPCPRPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFEAGLCGWSHLAWPGLGGYSW
DWSSGAAPS-RYPQPLVDHTLGTETGHFVLFETHMLGPGGQAAWLHSQPLPATE--ASCL
RFWYHMGFPEHFYKGQLRVLLNSARGQLAVWSMGGRLRHQWLLGQVEVASAEEFQIVFEA
TLSGQPAVGPIALDDVEYLDGRHCQLSAPGRGQPAPPQIRDSVRLAAVGGALVVL-VLLV
-LLGLAGRRWLQK-G----GCPSRGE-----TAAVAPGFDNIVFNADGVTL-PASLTDSQ
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAACNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEQDSCGWQDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGPW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLEFWD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPAPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 827)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRDC

ENSGT00720000108445_1_Linker_4_5 (827, 840)

SPTVTTERDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRRVESRGPDHDHTTGQ---GHFVLLDPTDPLVWGHSAHLLS
RPQVPAAPMECLSFWYYLHGPQIGTLRLAMRQEGE-DTHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAMRPGPCWAPHHCSFEDSDCGFSSGGWGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWRLGSVDVQA
ERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHVGFPEHFYKGELRVLLRSAQGELAVWGTGGHRRHQWLEAQVEVASTNEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTAVGGALLLL-MLLV
-LLGLGGRCWLQKRE----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--CPRASHFTS----PG-LGLLICGALGQSEAINRCGSPAPSVCNFVCDCRDCSDENHCG
YHKESPAL----------------GAPFACDLEQNSCGWRDVSTSAYRWLRDRAGAAVVG
GPAPRSDHTWGTDLGKG------GHSGRGAGGPRARTPALTACGAPARSP-------EPC
REERPDPGELRVELTHGRETLILWQSAGPV-GDFWKELVVPTGRVPGSFWVRQRESGR--
---GEERS---------------------RGA--GDRERPGGTCLPTLL---QLGPAGRK
DLASKPGFATRPLCDLGQI-------AALLCTS-VPSSVEWGLRPGAPR-----------
----------GTWTASDPTSSPEGKA-PGRGLGRDLGLG----AGALA----SRTPVLLS
----------PQ

PF00629 // ENSGT00720000108445_1_Domain_2 (493, 584)

LTFYYYLHGSEGGSLLLFQQPLTPVPPSAPKAPARFPLRSRAGDLGVA
WVRDVVQIRSDLPFQI--ILEGKTGP--GGVVGLDDLILSQGCRELPEPRFPPTETPSPR
TAGTPAPVSPGP------ARSFSSAEDPCGPGQFACDD-RCLRDEQRCDFIAQCTDGTDE
EGCAGGPP----VCGPGEAGSPGRGQTLTC----IGRPP------VSASAGHFLSLQKAP
GKLLGLARARTLPLGPSGPDCTLHLAYFLQSGP---------------------------
-------------------------------------------------------GELS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFEKGPCGWYPERRSDAVWSRSRIHGPGYDHTTGR---GYFMYLDPTAPPARGPRAHLLT
APQVPATSIQCLSFWYHLYGPQIGTLSLLLRRPGQPDARLWARAGTHGNRWHEGWATLHH
-PDPTGRFQLVFEAERNAFHGNMALDDITVRPGPC

ENSGT00720000108445_1_Linker_5_7 (996, 1112)

WAPRRCSFEDSDCGFSSDGPGGWKR
RGDIAG-GAAVGPGPGTDHTTETAQGRGRRA---------------------GGSGRRER
QLSTAAVSVAW-PLGTVAA-GALAFPLGGLG

PF00629 // ENSGT00720000108445_1_Domain_7 (1112, 1174)

GRK---HQVFRVSDRGGFTWRLGSIDVRA
DGAWKVVFEAVGTGREHSYVAVDDLHLQDGPCP

ENSGT00720000108445_1_Linker_7_8 (1174, 1178)

QPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESNMCGWSHRPWPGLGGYSW
DWSGSATPS-RYPLPPVDHTLGTAAGHSAFFDTGVLGPGGRAAWLLSEPLPATE--VSCL
RFWYHVGFPEHFYKGELRVLLGNARGQLGVWGAGAQLRHQWLEAEVEVASPEEFQIVFEA
TLGGQPVTGAIALDDITYQAGRRCRTPAPVEEETPRVS----SVAVGVAGAILAT-VLLG
-LVAVGGRRWIKQKK----GGPFARKSV---EGVVAPGFENVVFNEDRVTL-PSVTGDQ-
--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------GPPPPR

PF00057 // ENSGT00720000108445_1_Domain_1 (350, 391)

TQGPDIDLGQH
HCRNKACVEPHQLCDGEDNCGDRSDEDPDT

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CSHHTA

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 585)

TDFETGLGLWNQS-----------
----------EGWSWDHSTGGLEHPAWPRRDHSQNSAKGSFLISVAKP----SAPAILSS
PEFQASGTYHCTLVFYYYLHGSEAGSLQLFLQSQDPGAPQTP-----ILLRSRRGDLGDI
WVRDQVDVQSMHPFRI--LLIGQTGP--GGVVGLDDLILSDRCAPVLGEPT---SRSPY-
---QLIAP----------PTLPPQPQDSCEPEHLSCGD-LCVPLEQLCDFQQQCAGGEDE
LQCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 828)

TDFES--TAGGWEDASVGQLQWQRLAAQESGSPAEEC---SSCPSGHFLSLQKAW
GQLVAAASVLTPPLGPSGPACELHMAYYFQSHPQGLLALVTVE--DGSRELVWRAPGSSN
GS-WTVHTVPLGEHRRPFRLEFVGLVDLDGPGQQGAGVDNVTLRGCS

ENSGT00720000108445_1_Linker_4_5 (828, 840)

PTVTTEKDREIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 997)

C
NFERDMCGWHAGHLAGTRWHRVKSSGPGYDHTTGQ---GHFMLLDPAEPLARGPSAQLLT
GFQMPAGPTECLSFWYHLHGPQIGTLLLAMRQEGAVEMALWSRSGSHGNRWHQAWATLTH
QP--GFKYQLLFEGLRDGFQGTMGLDDVTVRPGPCWAPRRCSFEDSACGFSTGGQGLWRR
QTNATG-QAVR--GPWADHTTETPQ--------GHYMVVNMSPQALSHGHVATLTSEEHG
PLAQPACLTFWYHLSLQSP-GTLR--VHVEEGER---HQVLSISAHGGLAWRLGSIDVQA
ERAWRVVFEAEAAGVEHAYIAVDDLFLEDGPCPRPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFESGLCGWSHLPWPSLGGYSW
DWSSGATPS-RYLQPSVDHTLGTEAGHFAFFETSVLGPGGRAAWLRSEPLPATE--GSCL
RFWYHMGFPEHFYKGELRVLLSSARGQLAVWGADRHQRHQWLQGQVEVANPEEFQVIFEA
TLGGQPTLGPIALDDVEFLAGQPCHVPAPSQGDRPVPV----SVPVVVSGALLFL-LLLG
-LLGLVGRRWLQKRG----CCPLLGRRE---TGAAPPGFDNVLFNADCVTL-PTPPITSD
P-------------------

------------------------------------------------------------
--MYLPSHLLSTLVLL--MSLPAAQSLGKTWVPSHCRSPIEAVCNFVCDCGDCSDEAQCG
FHGALTTL----------------STPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CNFEQDPCGWQDISTSGYRWLRDRAGAV-LD
SPGPRSDHTHGTDL--GWYMAVGTHHGKEASTATLRSPVMREAAPTCELRLWYHTASR--
-----DIAELRLELTHGVETLTLWQSSGPW-GPGWQELVVNTGRVQGDFKV---------
-------------------TFSATRNATHRGAVALDDVEFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

SCPLGHH
HCQNKVCVESHQLCDGEDNCGDRSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQL-----------
----------EGWTRNYSAGSMVTPAWPHRDHSRNSAYGFFLISVAKP----GTTAVLFS
PEFQASISDNCSFTFYYYLHGSEASRFQLFLQAQGLNTPQEP-----VLLRSHHGELGTA
WVRDRVDIQSVHPFRI--LLAGKTGP--GGIMGLDDLIMSNSCRLVPDMST--LQSSRS-
---GPEALALSP------QTFIKLPQEACKPGHLSCGE-LCVPPEQLCDFQQQCAEGEDE
QKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFEST-SAGGWEDISVGKLQWQRLGAQN-GKPAKDA---HQDIPGHFLSLQKAW
GQLRSEARALTPALGPSGPRCELHMAYYFHSHPQGFLALVVVE--NGFRELVWQAPSS-S
SGGWTVEKVLLGARHRPFQLEFVGLVDLDGPGQQRAEVDNVTMRDCNPTVTTESDQEVSC
NFERDSCSWHTVHLTDAHWHRVKGHGSEYDHTTGQ---GFFMFLDPTDPPARGQAAVLLT
RPQVPLVPKECLSFWYHLYGPQIGTLHLAMRKDGEEDTLLWSRSGTHGNHWHQAWVTLHH
QLEVNTKYQLLFEGLRNGYHGTMALDDVAVRPGPCWAPRS

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSPGGLGLWKR
QGNASG-YVPW--GPWTDHTTETAQ--------GHYMVVDTSPNVLPKGQVASLTSEEHQ
PLTQPACLTFWYHLSLHNP-GTLR--VHVEESTR---RQELSISAHGGFTWRLGSVNVQA
TQAWRVVFEAVAAGVEHSYMALDDLLLRDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

AQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWSSGATPS-RYPRPTVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATT--ASCL
HFWYYMGFPEHFYKGKLRVLLSSAQGQLAVWEQGSHLRHQWIQVQIKVSNSEEFQIVFEA
TLGGQPALGPIALDDVQYLAGQHCQKPPSSQGEMAA-P---VSVPVAVGGALLFF-VFLV
-LLGLGSWHWLQK-Q----RCPFQRS-----TDTATSSFDNILFNADQVTL-PESITSSS
PDKAW---------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAVCNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLRDAAPSCQLRLWYHAASG--
-----DVAELRLEVTHGSETLILWQSTGPW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPELPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQPP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVLEVST--LQPLPP-
---GPWAPAPQP------LPPSSRLQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGRLQWRRLSAQESQGSSAAV-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTERDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAVPTECLSFWYHLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGTRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHHCSFEDSDCGFSSGGQGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGGK---HQVLSLSAHGGLAWRLGSVDVQA
QRGWRVVFEAVAAGVAHSYVALDDLLLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATP--VSCL
RFWYHMGFPEHFYKGELRVLLSSAQGQLAVWSTGGHRRHQWLEAQVEVASTNEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAV-P---VSVPTVVGSALLLL-MLLV
-LLGLGGRRWLK-RG----SCPFQSN-----TEATAPSFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------FLALAVVDG-GGSWELAWQAGSS-S
ARDWKVASVLLGERSRPFRLEFVSLVDLDGPDHQGAGVDNVTLKDCSPAVTTDRDKEIS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCGWYPSHLTDTHWRRVESHGPGYDHTTGR---GHFVLLDPVAPPARGRSACLLS
RPQEPAAPEECVSFWYHLHGPQIGTLRLAMRQEGK-DTPLWSRSGTHGNRWHQAWATLAH
QPGSGAQYQLLFEGLRDGYHGTMALDDLALRPGPCWAPRRCSFEDSACGFSTGGQGLWRR
QTNASG-HAAW--GPPADHTTETAQ--------GHYMVVDTSPSALPRGRGASLTSEEHR
PLTQPACLTFWYHLSVRSP-GTLR--VHLEETER---RQVFSVSTHGGLAWRLGSVDVRV
ERAWRVVFEAVAAGVERSYVALDDLFLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPGLGAYSW
DWGGGATPS-RYPQPPVDHTLGTEAGHFAFFETGVLGPGGQAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGALRVLLSSAQGQLAVWGADGRMRHQWLKAEVEVASTEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAASQGAAAP-R---VSAPAAAGGAILFI-TLLV
-LLGLGRRCWLQRKR----GCPCWSN-----TETTATGFDNILFSARVTSD-P-------
--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MAPMTVGICQMSPPRELTLSYPHSAPLNLP

PF00057 // ENSGT00720000108445_1_Domain_1 (355, 391)

CGPDKW
RCNRGSCVHLEQLCDGTDDCGDLSDESTPA

ENSGT00720000108445_1_Linker_1_2 (391, 415)

CRSFTVCSFEEDWCGWGGLWSFTV

PF00629 // ENSGT00720000108445_1_Domain_2 (415, 583)

CSFEED
WCGWSAGPNGPSWLRNSSLHLTPGARRPSRGHSTNSRTGFFLYVSTAPPDLSSGAARLIS
PTFQATTTNSCSLVFYSYLYGSATSSLNIYYQTNST----------MGLVHTWAADRGDY
WFRNKVDFSVTERFQI--LLEAVIGAGHKGSVALDDLVLSPG

ENSGT00720000108445_1_Linker_2_3 (583, 628)

CLQATGN---LTITPG--
--------PAS-----------PGPTT

PF00057 // ENSGT00720000108445_1_Domain_3 (628, 663)

PCAPEEFACDNEKCIRPELACDFTDTCEDGSDE
TS

ENSGT00720000108445_1_Linker_3_4 (663, 667)

CGAS

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

TFEA--GAGGWKDISVGQLQWVRENGSTASEPRA--DHTTNSSAGHYLGVGLAP
GQMLSVARARTPPLGSSGLACSLEMHYWLHSDPQGFLALSILDPGLGTHRLAWHMQGT-D
STAWKHVTVPLGKRVRPFQLELTALVKLRGLVMQSAAVDDIVFVN

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CDPHFTPPDASELS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERGLCGWYQDQSDDFEWMR----GLGSDHTTGT---GYFLAVDLAAQSARGLSARLIT
YPQDCPTREQCLSFWYRLDGPQSGTLSLKIQHDEEPETVLWTRTGAHGSTWHLGFATLRC
QALQGYR--LVFEALRSGYLGDIALDDVTMRAGACGPQESCSFEANACGFSSSWQYLWAR
QSNATG-TATA--GPPTDHTLGTAR--------GYYMIVDTSKGSLPHGQTATLSSGQYR
PLTHPRCLCFWYQLSPSDP-GSLT--VHVEEKGL--QRSLFSVSSVHGDAWHRGQVTVQT
AEAWKVVFKAVGAGGQLSYIALDDLHLQASSCPEPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1271)

CDFESDTCGWTSPSDPTVGSYAW
GWRSGISL-----GPEVDHTLGTTAGHYAYFDASVLAPGGHVAWLLSEHLPATA--GACL
WFWYHMDFQEHFGAPCQPLQV-PAFGSGTTWTFRSTSTAAS-------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

------------------------------------------------------------
--MCRPGHLLAT---L---ALLTAGSLGGAWDPSYCRSPREAVCNFVCDCRDCSDEQRCG
FHGAAPAP----------------GTPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFEQDPCGWHDISTSGYSWLWDRAGAG-L-
--AAHTDHTLGTDL--GWFVAVDTHRGKEPSTAALRSPLLRQAAASCQIQLWFHAFSG--
-----DVAELRLELTHGTETLSLWRSSGPW-DRGWQELMVATGRIRGDFQV---------
-------------------TFSATRNATHRGAVALDDVAFWDCG

ENSGT00720000108445_1_Linker_0_1 (345, 353)

LPTPR---

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

TSCSLGQH
RCQNKACVEPHQLCDGEDNCGDRSDEDLDT

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CGRHTA

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 585)

ADFETGLGLWDSS-----------
----------EGWSRNNSTGGHGHPAWPHRDHSLNSAKGFFLI-VADP----VAPAVLSS
PKLRASGAAPCTFVLYHYLHGSEAGSLQLSLQSQDPAAPWTS-----ILLRSRRGELG-D
WVRDQVDIQSAHPFQI--LLVGQTGP--EGVVGLDDLILSEHCTPELEPSVL--------
------------------QTLPPQRQDSCEPGHLSCGE-LCVPPEQLCDFQQQCPGAEDE
QQCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 744)

TDFES--SAGGWEDASVGRLQWQRLAPQESG------------TAGHFLSLQRAW
GQLETAARVLTPALGPSGPACELHLACCFQSQP---------------------------
-------------------------------------------------------QEVSC
NFERDMCGWHIGHLTDVHWHRVKSSGPDYDHTTGR---GHFVLLNPTEPLARGPGAQLLT
GLQMPAAPTECLSFWYYLHGPQIGTLLLAVKPEGAEETVLWSRSGSHGNQWHQAWATLSH
KP--GSKYQLLFEGLRDGFQGTMGLDDVTMRPGPCWAPRR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CSFEDSACGFSTDGQGLWQR
QSNASG-QAAW--GPQADHTTETAQ--------GHYMVVNMSPQALPHGHVASLTSEEHA
PLAQPACLAFWYHLSLGNP-GTLR--VHVEEGGR---QQVLSISTHGGLAWSLGSVEVQA
ERPWRVVFEAEAAGVEHSYIAVDDLSLQDGPCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

RPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFESGLCGWSRLAWPGLGRYSW
DWSSGATPS-RYLQPPVDHTLGTAAGHFTFFETGVLGPGGRAAWLRSEPLPATE--GSCL
RFWYHMGFPEHFYKGELRVLLGSARGQLAVWAAGGRQRHQWLQGQVEVASPEEFQVLFEA
TLGGQPALGPIALDDIEYLAGQACRMLAPSQGGGYMHA----SVPIVISGAFLFL-LLLG
-LLALGGRHWLRKRG----DCPIVGSRE---AG-AALGFDNVLFNA--------------
--------------------

------------------------------------------------------------
----------------------------------------EKLCNFVCDQWDCSDEKHCG
YHKESSLL----------------GRAFS

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFEQDDCGWTDVSTSSYRWVRERRTFS-RW
GTRPHGDHTLRNRW--GWFMATGGHTGKAAATASLQSPILRNAAATCEIHLHYHIWAPDA
---TTINGTLSVQLTDKTQTYNLWVGPKSS-VLGWRQTVIYPGRIRGQFQL---------
-------------------IVVSSRDPSSQGDIAIDDLEFRHCG

ENSGT00720000108445_1_Linker_0_1 (345, 353)

LSAPQ---

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

LACPAGYH
QCPLGPCVMPESLCDGTDDCGDNSDES--N

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CTGHRF

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 569)

CNFETDSCQWDST-----------
----------APNSWHRANGI---GSKPSRDHTSANRNGEYLTAMVEN----GSSAELSL
PTQPS--NEPCSVVLYYLMDGSDGNRLLISSQKGN---------EAKKVLAERQGQRGQV
WLREKVTLQLPDPEHTSDLLSGVQTS--RGN--APTLTLRQRAHPIPRPTVPPYPSAN--
-VSHPIPRPTCPTL-TLGQRAHPNPRPT-------CPT-LTLGQR---------AHPNPR
PTCP-TRFLFNNNAANWTDLSIGKLKWGADNGALPGGD-------TRSKGGQYLGVQQAQ
GNLLVGAETRSPTLCAVGPTCAVKMTYYFNSGPAGSLSLSLWDPESGAHSHIWGSQGE-S
RPEWRSVVIPVGERKQQFQLVLVGSVEPLPRGDWGAAVEEIQFIDCGIKQLTVDEAPVTC
NFESGTCGWYQDPTDDMDWI----MGAQGDHTTGK---GNFIYVDGGSRTDRGMKARLLT
YAQSSAGDSQCLSFYYRVWGPDAGTLILSSIIDGK-ETLLWTGTGTHGNRWHHESVTLTI
--PTAGKYQLALDAVRDGSVGNMAVDDITLRPGACAAPTR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CTFEAGTCRFKSEGQYRWKL
NQNQNANPSGPQPGPFFDHTLQSIA--------GHYMVVDTSSTALPRRASAVLTSDTYG
ALPAPGCVSFWSQFGGDQS-GTLN--VYVVEGKKKEMRKLLSASRTHGDNWAYRSATIHP
GGTWELRFEAVGAGGDRGHVALDDIHISHHPCH

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

EPAA

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFESGFCAWSNVRFPLVDTYDW
DSTNGAGQFLKKTAINEDHTLGTKEGHYAFVDTGSLHTEGSSAWLTSEQLPATS--GSCF
SFWYRTDAGDHYHAGELVLFMSSAQGLRPVWVLHGQHSNAWQEQQLQLDSTVDFQFVFEA
SKGSRPHSATVALDDLKYVTGRSCDAKQEQEGEHGRGGKTNAGT----ILAVLLG-VLLG
LLCGAIGYLIYRKRKKNQAGAP-----SGFGPGDGVEGFDNVAFEDGPEVFSPPEITSVP
--------------------

------------------------------------------------------------
--MPIKMHLLRGLVLMEELVLALPPSWAQPAFVNRCRTASQKLCNFVCDCWDCSDENQCG
FQRDSVVL----------------GRPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CDFEGSLCGWEDISPSAFQWVPVQASLS-NW
DQEPPFDHTRGTDL--GWYLAPTKQQVKPSATARLRSPPMREASAACEIHAWFHLSGAAL
--S--------LELSAENYTVTLWRSPLPSSASPWRELVAFTGRIQGAFQL---------
-------------------IFSATQNFSTSVQVALDDLEFRN

ENSGT00720000108445_1_Linker_0_1 (343, 353)

CGLPDPGSRP

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 389)

PRCGPDEL
LCGNSTCLAEDRFCDGSEDCLEGDDEDP

ENSGT00720000108445_1_Linker_1_2 (389, 398)

AVCASFSAS

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 582)

RFEEGWGHWRPE-----------
------LDQGLLWTRNSSLHVAS--TSPLRDHSTNSPEGEFGNHGDLGPKQ--RRGWLLS
PTLAASKTEPCYLVLYLYLHGSDTNSLEVYYRTEEK----------MELVRSRTGDLGNF
WFRDKVAFDVKEKFQI--VIEGAFGTGDKGSIALDDLILSPGC-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

------------------------------------------------------------
--MHLPSHLLSTVALF-----MAAQSLGKTWVPGHCRSPVEAVCNFVCDCGDCSDEAQCG
FHGASTSP----------------SSPFS

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CSFEQDSCGWRDISTSGYSWLRDRAGAV-LG
GPGPHSDHTQGTDL--GWYMAVGTHHGKEAATATLRSPVMREAAPTCELRLWYHTASR--
-----DAAELRLELIHGVETLTLWQSSGPW-GPGWQRLAVNTGRVQGDFKV---------
-------------------TFSATRNATHRGAVALDDVEFRDCGLPVPQ---ASCPLGQH
HCQNKACVEPHQLCDSEDNCGDRSDEDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQL-----------
----------ENWTRNCSAGSVVSPAWPHRDHSQNSAYGFFLVSEAKP----GTAAVLFS
PEFQASVLYNCSLTFYYYLHGSEASRLQLFLQAQGLNATQAP-----VLLRSHRGELGTA
WVRDRVDIQSAHPFRI--LLAGETGP--GGIVGLDDLIISNYCRLAPGPPL--A------
----------------------CPGKNACEPGHLSCGE-LCVPPEQLCDFQQQCAEGEDE
WKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFESA-SAGGWEDISIGKLQWQRVEVQN-RKPARDA---NWDVPGHFLSLQKAW
GQLRSEARALTPALGPSGPHCELHMAYCFHSHPQGFLALVVVQ--NGFREMVWQAPSS-S
SGRWTVEKVLLGARHRPFQLEFVSLVDLDGPGQQRAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CDPTVTTKSDQEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDSCSWHTSHLTDAHWHRVRSHGSEYDHTTGQ---GFFMFLDPTDPPARGQGALLLT
RPQVPLAPKECLSFWYHLYGPQIGTLRLAMRKDGEEDTLLWSRLGTHGNRWHQAWVTLHH
QLEARTKYQLLFEGLRDGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGLGLWKR
QSNASG-HAPW--GPWIDHTTETAQ--------GYYMVVDTSPNVLPKGHVAFLTSEEHQ
PLTQPACLTFWYHFSLHNP-GTLR--VHVEEDTR---RQELSISAHGGFAWRLGSVNVQA
EQAWRVVFEAVAAGVERSYMALDDLLLRDGPCAQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSYQAWPSLGGYSW
DWSSGATPS-RYPRPTVDHTLGTEAGHFSFFETSVLGPGGQAAWLRSEPLPATT--ASCL
RFWYYMGFPEHFYKGELRVLLSSARGQLAVWSQGGRLRHQWIRAQIQVSSSEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQQPAPSQGEMAA-A---VSVPVAVGGALLFF-VFLV
-LLGLGGWRWLQK------RFPFHRS-----TDTASSGFDNILFNADQVTL-PESITSSS
PTRQGLAPHANSHSIQPSDA

------------------------------------------------------------
--MPLPGHLLP--ALV---LLLAAGSPGWAWVPNNCRAPREATCNFVCDCPGCSDETQCG
YHGASPTP----------------GAPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 357)

CDFEQDSCGWQDISTSGYSWLRDRAGAT-LE
ALGPRADHTLGTDLGPGWYMAVGTHRGKEASTAALRSPVLHNAAPSCELRLWYHAASG--
-----DVAELRLELTHRAETLTLWQSSGPW-GPGWQELVVATGRIQDDFRV---------
-------------------SWGGLGAGASREGFRVA-VMGCPSSISAPQ---AHCPLGHHHCQNMACVEPHQLCDGEDDCGDGSDEDAPACRHHTVTDFETGLGLWNHS---------------------EGWARNHSAGT-RPPAWPRRDHSRNSAHGSFLVSVAEP----SAPAVLSSPEFQASDTRNCSLVFYHYLHGSEDGSLQLFLQTQSPGSPQGP-----VLLRRRHGDLGAAWVRDRVDIQSERPFRI--LLTGHTGP--GGVVSLDDLILSDHCQ--PVPAPTEVSSPPP----GLWAPAPWT------QLSSLLPQDFCEPGHLSCGD-LCVPPEQLCDFQQQCEGGEDERECGTTDFESP-AAGGWEDASVGRLQWGRLQAQESRGPGTEA---GRAAAGHFLSLQRAWGQLAAEARVLTPPLGPSGPRCELRMAYYFHSDPQGFLALAVVG--GGSRELVWQAPSS-SKG-WKVDTVLLGARRRPFRLEFVGLVDLDGPGEQGAGVDDVTLKDCSPVTATDKDSEVSCNFERDTCGWHTGHLTDSHWRRIQSRGPGYDHTTGQ---GYFLLLDPTDPPARGPGAHLLTQPQAPAAPQECLSFWYHLHGPQIGTLRLAVRREGEAETLLWSRTGTHGNRWHEAWATLHHQLGSGAKYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPRRCSFEDSACGFSSGGQGLWTRQANATG-HASW--GPRTDHTTETAQ--------GHYMVVDTSPQALPRGHVASLTSEEHRPLAQPACLTFWYHLSLRNP-GTLQ--VHVEEAGR---RQVLSISAHGGFAWRLGSVDVQAERAWRXXXXXVAAGVEHSYVALDDLLLQDGPCPRPASCDFEAGLCGWSHLPWPGLGGYSWDWSSGATPS-RYPQPPVDHTLGTETGHFVLFETGVLGPGGRAAWLRSQPLPATK--ASCLHFWYRMGFPEHFYKGELRVLLNSERGQLTVWSTGGHLRHQWLEGQVEVASAEEFQIVFEATLSGQPALGPIALDDVEYLAGQHCRLPASSQGDTALAT----SVPTVVGSALLAL-VLLV-LLGLLGRRWLQKKG----GCPSRGE-----TTAVAPGFDNIVFNADCVTL-PASLTDHQ----------------

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

AHCPLGHH
HCQNMACVEPHQLCDGEDDCGDGSDEDAPA

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CRHHTV

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 587)

TDFETGLGLWNHS-----------
----------EGWARNHSAGT-RPPAWPRRDHSRNSAHGSFLVSVAEP----SAPAVLSS
PEFQASDTRNCSLVFYHYLHGSEDGSLQLFLQTQSPGSPQGP-----VLLRRRHGDLGAA
WVRDRVDIQSERPFRI--LLTGHTGP--GGVVSLDDLILSDHCQ--PVPAPTEVSSPPP-
---GLWAPAPWT------QLSSLLPQDFCEPGHLSCGD-LCVPPEQLCDFQQQCEGGEDE
RECGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 828)

TDFESP-AAGGWEDASVGRLQWGRLQAQESRGPGTEA---GRAAAGHFLSLQRAW
GQLAAEARVLTPPLGPSGPRCELRMAYYFHSDPQGFLALAVVG--GGSRELVWQAPSS-S
KG-WKVDTVLLGARRRPFRLEFVGLVDLDGPGEQGAGVDDVTLKDCSPVTATDKDSEVSC
NFERDTCGWHTGHLTDSHWRRIQSRGPGYDHTTGQ---GYFLLLDPTDPPARGPGAHLLT
QPQAPAAPQECLSFWYHLHGPQIGTLRLAVRREGEAETLLWSRTGTHGNRWHEAWATLHH
QLGSGAKYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPRR

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1174)

CSFEDSACGFSSGGQGLWTR
QANATG-HASW--GPRTDHTTETAQ--------GHYMVVDTSPQALPRGHVASLTSEEHR
PLAQPACLTFWYHLSLRNP-GTLQ--VHVEEAGR---RQVLSISAHGGFAWRLGSVDVQA
ERAWRXXXXXVAAGVEHSYVALDDLLLQDGPCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

RPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFEAGLCGWSHLPWPGLGGYSW
DWSSGATPS-RYPQPPVDHTLGTETGHFVLFETGVLGPGGRAAWLRSQPLPATK--ASCL
HFWYRMGFPEHFYKGELRVLLNSERGQLTVWSTGGHLRHQWLEGQVEVASAEEFQIVFEA
TLSGQPALGPIALDDVEYLAGQHCRLPASSQGDTALAT----SVPTVVGSALLAL-VLLV
-LLGLLGRRWLQKKG----GCPSRGE-----TTAVAPGFDNIVFNADCVTL-PASLTDHQ
--------------------

------------------------------------------------------------
--MCLPSHLLSTWVLFM-VTLPAAQSLGKTWLPNHCRSPIKAVCNFVCDCGDCSDETQCG
FHGASTIP----------------STSFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CNFEQDSCGWQDISTSGYRWLRDRAGAV-LH
GPGPHSDHTHGTDL--GWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHIASR--
-----DVAELRLDLTHGVETLTLWQTSGPW-GPGWQELAVNTGRIQGDFKV---------
-------------------TFSATRNATHRGAVALDDVEFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPIPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

RCPLGHH
HCQNKACVEPHQLCDGEDNCGDRSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQL-----------
----------EGWTRNHSAGSMVSPAWPHRDHSRNSAYGFFLISVAKP----GTTAVLYS
PEFQGSVSNNCSFTFYYYLHGSEASHFQLFLQAQGLNTPQVP-----VLLRSRHGELGTA
WVRDRVDIQSAHPFRI--LLAGETGP--GGVVGLDDLIMSSHCMLVPAMST--LQSSLS-
---GPVPLALYP------QTSIKLPQQTCEPGHLSCGD-LCVPPEQLCDFQKHCAEGEDE
HKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFESA-SAGGWEDISVGKLQWQWVEAQEKSKPAGDA---NRDAPGHFLSLQKAW
GQLRSEARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVE--NGFRELLWQAPGG-G
SGSWTEEKIILGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CNPMVTTESDQELS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQ---GFFMFLDPTDPPARGQGALLLT
RPQVPVVPKECLSFWYRLYGPQIGTLCLAMRREREEDILLWSRSGTHGNRWHQAWVTLHH
QPEASTKYQLLFEGLRNGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTH
QSNASG-LASW--GPWIDHTTGTAQ--------GHYMVVDTSPNVLPKGHVAALTSEEHQ
PLSQPACLTFWYHMSVPNP-GTLR--VHVEESTR---RQELSISAHGRSAWRLGSVNVQA
EQAWKVVFEAVAAGVEYSYMALDDISLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFETGLCGWSHLPWPSLGGYSW
DWSSGATPS-RYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATT--VSCL
RFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGHLRDQWLQVQIELSNSEEFQIVFEA
TLGGQPALGPIAIDDVQYLAGQQCKQPSPSQGEVAA-P---VSVPVAVGGALLFF-MFLV
-LMGLGGWHWLQK-Q----HCPGQRS-----TDAAASGFANILFNADHVTL-PESITSNP
QSPPDLA-------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAACNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGKEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLILWQSTGPW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLA

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPVPQP------LPPSSRLQDSCKQGHFACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-EAGGWEDASVGQLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGARRRPFQLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTKRDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYYLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHHCSFEDSDCGFSSGGRGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGRK---HQVLSLSAHGGLAWRLGSVDVQA
EQAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGATPS-RYPQPPVDHTLGTKAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHMGFPEHFYKGELRVLLRSTQGQLAVWGTGGHRRHQWLEAQVEVASTKEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFNADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
--MPLPSHLLPALVLLL------ARSPGWAWVPSHCRSPGQAACNFVCDCRDCSDEAQCG
YRGASPA----------------LGTPFA

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDSCGWRDISTSGYSWLRDRAGAA-LE
GPGPHSDHTLGTDL--GWYMAVGTHRGEEASTAALRSPTLREAAPSCKLRLWYHAASG--
-----DVAELRLEVTHGSETLTLWQSTGPW-DPGWQELAVTTGRIRGDFRV---------
-------------------TFSATRNATHRGAVALDDLA

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCPLGHH
HCQNKVCVEPQQLCDGEDNCGDLSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CGRHTAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 584)

DFETGLGPWNRS-----------
----------EGWSRNHSAGGPERPSWPRRDHSRNSAQGSFLVSVAEP----GTPAILSS
PEFQASGASNCSLIFYHYLHGSEAGCLQLFLQTLGSSAPQAP-----VLLRRRRGELGTA
WVRDRVDIQSAHPFQI--LLAGQTGP--GGVVGLDDLILSDHCRPVPEVST--LQPLPP-
---GPWAPVPQP------LPPSSRLQDSCKQGHFACGD-LCVPPEQLCDFEEQCAGGEDE
QACGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFESL-KAGGWEDASVGRLQWRRLSAQESQGSSAAA-------AGHFLSLQRAW
GQLSTEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVD--NGSRELAWQALSS-S
AGGWKVDKVLLGAHHRPFQLEFVGLVDLDGPDQQGAGVDNVTLRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTKRDREVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQ---GHFVLLDPTDPLAWGHSAHLLS
RPQVPAAPTECLSFWYYLHGPQIGTLRLAMRREGE-ETHLWSRSGTQGNRWHEAWATLSH
QPGSRAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPHHCSFEDSDCGFSSGGRGLWRR
QANASG-HTAW--GPPTDHTTETAQ--------GHYMVVDTSPDALPRGQTASLTSKEYR
PPAQPACLTFWYHGSLHNP-GTLR--VHLEKGRK---HQVLSLSAHGGLAWRLGSVDVQA
EQAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPRPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWGGGGTPS-RYPQPPVDHTLGTKAGHFAFFETGVLGPGGRAAWLRSEPLPATP--ASCL
RFWYHVGFPEHFYKGELRVLLLSTQGQLAVWGTGGHRRHQWLEAQVEVASTKEFQVVFEA
TLGGQPALGPIALDDVEYLAGQRCQQPAPSPGDTAA-P---VSVPTAVGSALLLL-MLLV
-LLGLGGRRWLQKRG----SCPFQSN-----TEATAPGFDNILFDADGVTL-PASVTSDP
--------------------

------------------------------------------------------------
------------------------GSPSRSWVPNYCRTPSEAICNFVCDCWGCTDEAHCG
YHGTSNSL----------------GAPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CNFEQDTCGWRDISTSGYSWLRDRAGAT-PE
GPGPHSDHTLGTDM--GWFMAVGTHRGKEAATAALRSAVMHEAVPTCELRFWYHAGSG--
-----DVAELRLELTHGVETMVLWQSAGPW-HPGWQELMVTTGRIRGSFWV---------
-------------------TLSATRNATHRSAVALDDLAFQGCG

ENSGT00720000108445_1_Linker_0_1 (345, 353)

LPVPQ---

PF00057 // ENSGT00720000108445_1_Domain_1 (353, 391)

ASCPLGHY
HCTNQACVEPHQLCDREDNCGDGSDEDADF

ENSGT00720000108445_1_Linker_1_2 (391, 397)

CSQHTV

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 585)

TDFETGLGPWNHS-----------
----------DGWTKNHSTDGPPFSAWPRQDHSQNSAHGSFLVSKADP----SDPAVLFS
PKFQASDPQNCSLVFYHFLHGSEAGQLRLFLQTQGPGNPEGP-----VLLRRRRGELRAA
WVRDRVDIQSKHPFQI--VLVGETGP--GGVVGLDDLILSAYCRPVPDQSGQPLG-----
-----------L------PILSPQPQDFCEPGHLACGD-LCIPTXXXXXXXXXXXXXXXX
XXXXXXXXXXX-XXXXXX-----XX--XXXXXXX-X-----X------XXXXXXXXXXX-
--XXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXX-----------------
---XXXXXXXXX-----X--XXX-XXXX-----------XXXXX-----XX-XXXXXXXX
XXXX----------X---------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00629 // ENSGT00720000108445_1_Domain_5 (895, 997)

XXXXXX
QLQATAVAQECLSFWYHLHEPQIGTLRLALRR-GEVDELLWSRSGTQGNRWHQAWATLHH
QLDSGTKYQLLFEGLRDGFHGTMALDDVAVRPGPCWAPKQCSFEDSDCGFSSGAQGLWRR
QNNATG-QVAW--GPHTDHTTQTPQ--------GSYMVVDMSPKSLPRGHKASLTSKEHR
PLAQPACLTFWYHLSLQNP-GTLR--VLVEEAER---QQVLSVSAQGGFAWRLGSVNVQA
EQAWRVVFEVVATGQEHSYVALDDLLLQDGPCPQPAS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFEAGLCGWNHLPWPSLGGYSW
DWSGGDIPS-RYPQPPEDHTLGTKAGHFALFETGVLGPGGRAAWLRSEPLPPTT--ASCL
HFWYHMGFPEHFYKGELRVLLHSAQGQLTVWGAGGHRRHQWLEGQVEVASTEEFQIMFEA
TLGGQPVLGPIALDDVEYLPGQRCQLPAPIQGDKAVDT----LVPAAVGGALFL--LLLV
-LLGLAVRHWLRKKG----GWPFQGE------TAPTSSFDNILFNSDQVTL-PATVTSDV
PSNQ----------------

------------------------------------------------------------
--MYLPSHLLSPLVLLM-VTLPAAQSLGKTWVPSHCRSPIEAVCNFVCDCRDCSDEAQCG
FHGASTTP----------------STPFS

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 343)

CSFEQDPCGWQDISTSGYSWLRDRAGAA-LD
GPGPRSDHTHGTDL--GWYMAVGTHSGKEASTATLRSPVMREAAPPCELRLWYHIPSR--
-----DVAELRLELTHGVETLTLWQSSGPW-GPGWQELAVNTGRVQGDFKV---------
-------------------TFSATRNATHRGAMALDDVEFRD

ENSGT00720000108445_1_Linker_0_1 (343, 354)

CGLPTSQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

SCPLGHH
QCQNKACVEGHQLCDGEDNCGDSSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQF-----------
----------EGWTRNYSAGSMVTPAWPQRDHSRNSAYGFFLVSVAKP----GTTAVLFS
PEFQASVSYNCSLTFYYYLHGSEASRLQLFLQAQGLSTPQDP-----VLMRSHHGELGTG
WVRDRVDIQSVHPFRI--LLVGETGP--GGVIGLDDLIVSNYCRLVPDVST--PQSSRS-
---VPEALALSP------QTSTKPPWEACKPGHLSCGE-VCVPPEQLCDFQQQCAEGEDE
QKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFESA-SAGGWEDISVGKLRWQQVEAQN-RKAAKDA---HRDIPGHFLSLQKAW
GQLRSEARALTPALGPSGPRCELHMAYSFHSHPQGFLALVVVE--NGFRELVWEAPSS-S
SGGWTVEKVLLGARHRPFQLELVGLVDLDGPGQQWAGVDNVTMRDCNPIVTTESDQEVSC
NFERDSCSWHTDHLTDAHWHRVKSQGSEYDHTTGQ---GFFMFLDPTDPPARGQAAILLT
RPQVPLVPKECLSFWYRLYGPQIGTLRLAMRKDGEEDTLLWSRSGTHGNRWHQAWVTLHH
QLEANTKHQLLFEGLRNGYHGTMALDDMAVRPGPCWAPKS

PF00629 // ENSGT00720000108445_1_Domain_6 (1001, 1173)

CSFEDSDCGFSPGGLGLWKR
QDNVSG-HAPW--GPWTDHTTETAQ--------GYYMVVDTSPNVLPKGHVASLTSEEHQ
PLTQPACLTFWYHLSLRNP-GILR--VHVQESTR---RQELSISAHGGFTWRLGSVNVQA
GEAWRVVFEAVASGVENSYMALDDLLLQDGPC

ENSGT00720000108445_1_Linker_6_8 (1173, 1178)

AQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPNLSRYSW
DWSSGATPS-RYPKPTVDHTLGTEAGHFAFFETSVLGPGGRAAWLRSEPLPATT--ASCL
HFWYYMGFPEHFYKGELRVLLSSAQGQLAVWEQGSHLRHQWVQVQIQVSNSEEFQIVFEA
TLGGQPALGPIALDDVEYLAGQHCQRPASSQGEMAA-S---VSVPAAVGGALLLF-MVLV
-LLGLGSRHWLQK-Q----RCPFQS------TDTATSSFDNILFNADQVTL-PESITSSS
PDKAW---------------

------------------------------------------------------------
------------------------------------------------------------
YHQESPSL----------------HAPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 345)

CDFEQDTCGWQDISTSGYRWLRDQAGSI-FG
NPELHSDHTFGTDL--GWYMAVGTHQGKEPAIAALRSPVLHEAAPTCEIRLWYH------
-----DVAELRMELTHNSETLVLWQSLGRLGGSGWQELVVATGRVQGDFWV---------
-------------------TISAKRNATHRGTVALDDVEFWNCGLPSPQ---NSCTRCQH
HCANFACVALTELCDREDNCGDASDEEGESC-GHKV

PF00629 // ENSGT00720000108445_1_Domain_2 (397, 585)

TDFENGLGEWTNE-----------
----------TGWMITQGSEASVL--SPVRDHSKNSASGFFLLSKADQ----GTPAVLVS
PAFHPLSTNSCLLTFYYYLHGSEAGSLQVFLQSQDPDSPQKD------LIRTRQGELGTA
WVRDKVTIHSKHPFRI--LLKGETGP--GGIVGLDDLNLSQHCQQVTDASPPKASVPGP-
-----LAGVPQPFQSS-------RFQDSCQPGYFSCGK-SCLFPEQLCDFVPQCAGGLDE
QNCXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------X---XX-X----
-----XXXXXX------------XXXXXX-------XXXXXXX--X---X----------
-------------XXX------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXLS

PF00629 // ENSGT00720000108445_1_Domain_6 (840, 1174)

C
NFERDSCGWYPEHQTDALWQRASKQGPGYDHTTNQ---GYFMYLDPTRPPARGKGSRLLT
ALQVSPAHNECLSFWYHLYGPQIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XXXX--XXXXXXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXX-XTLR--VHVEEDKR---RQVFIVSAHGGFTWRLGSVDVQP
ERAWKVVFEAVGAGVEHTYIAVDDLHLKDGPCP

ENSGT00720000108445_1_Linker_6_8 (1174, 1178)

QPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1346)

CDFESDMCSWSHTPWPGLGGYSW
DWSSGATPS-RYLQPSVDHTLGTETGHFAFFDTSVLGPGGQAAWLRSEPLPPTPMGGSCL
RFWYHMGFPEHFYKGELKVLLISSQGLLTLWGTGGHLRHQWLEGSVQVTSLVEFQIVFEA
TLGGQPVLGPIALDDIMYQTGQSCEPPMPVR-----------------------------
------------------------------------------------------------
--------------------

------------------------------------------------------------
--MQLPTHLLPVLVLLS-GELDAAQPLGRALVPGPCKSPIETQCNFLCDCTDCSDEAQCG
YSRASPG----------------LGTPVT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 340)

CDFEQDNCGWQDISTSGYRWVRDRARAQ-PE
GPVAHTDHTQGTDL--GWYMGVGTHRGTEAAVAALRSPVLREAGPTCELRLWYHAVSG--
-----DVAGLQLELTHSAETLTLWQSSGPW-SSGWQELAVTTGRIPGDFRV---------
-------------------TFSATRNATHKGAVALDDVE

ENSGT00720000108445_1_Linker_0_1 (340, 354)

FWDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 391)

SCALAHH
RCRNAACIEPHQLCDGEDNCGDRSDEDPLT

ENSGT00720000108445_1_Linker_1_2 (391, 398)

CSHHTGT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

NFETGLGLWSHT-----------
----------EGPAWNLSTSGPKGSAWPRRDHSRNSAQGSFLVSTAKP----GNPAVLLS
PQLQASGSRNCSLIFYHYLHGSKDAHLELLLWMQGPGAPQAP-----VLLRHRHGELGAA
WVRDQVDIRSAHPFRI--LLTGETGP--GGIVGLDDLILSDHCTVIPG------APLSP-
---VPWPEAPHP------QQSS--LQGSCEPGQLACGD-LCVPPEQLCDFQPQCAQGEDE
RECGTT

PF00629 // ENSGT00720000108445_1_Domain_4 (667, 826)

DFEAA-AAGGWQDSSIGRLQWGRQEAQGIRATAGEASLSSCSCPGHFLSLQRAW
GQLRAEARALTPVLGPSGPHCELHLAYYFHSHPRGFLALALVE--SGSRELVWQAPGD-S
SGAWTVVRVLLGAHRRPFQLELVALVDVEAPGLQGAGIDNVTMRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CSPTVTTETDREVT

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFEWGMCGWHLGHLTDVHWRRVESHSSGNDHTTGQ---GFFMLLDPAEPPARGRHANLLT
GPQVPAVPEQCLSFWFQLHGPRIGTLRLAMQRDGEEEIQLWSGSGTHGNRWHQAWATLRH
QLGPSSKYQLLFQGLRDGYDGIMALDDVTVRPGTCPAPQRCSFEESTCSFSTGGQGLWKR
QNSASG-TATK--GPWADHTTETAQGTLTLPPPGHYMIVATSPDMLPQGHVASLTSEEHQ
PLLHPTC--------------TLR--VRVEEGRQ---HQTLSISEHGGPAWRLGSMDVWA
EQAWKVVFEAVAAGVEHSYVALDDILLQDGPCPQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSQVAWPGLGGYSW
DWSSGATPS-RYSQPAMDHTLGTETGHFAFFETSVLGSGGRAAWLRSEPLPATK--ASCL
RFWYHMGFPEHFYKGELRVLLVSTRGQLVAWAQGGQLRHQWLEAQVEVVSSEEFQVVFEA
TLSGQPVQGPIALDDIEYLPRQHCQWPAPSPGEHLAEA-----SPPAVSGALVFL-TLLV
-LLGLTGWCWLRKGG----GWPFWRN-----RHSAAPGFDNILFNAVGAQD-GC------
--------------------

------------------------------------------------------------
--MYLPSHLLSTLVLL--M---AAQSLGKTWVPSHCRSPIEAVCNFVCDCGDCSDEAQCG
FHGALTTL----------------STPFT

PF00629 // ENSGT00720000108445_1_Domain_0 (150, 296)

CNFEQDPCGWQDISTSGYRWLRDRAGAV-LD
SPGPRSDHTHGTDL--GWYMAVGTHHGKEASTATLRSPVMREAAPTCELRLWYHTASR--
-----DIAELRLELTHGVETLTLWQSSGPW-GPGWQELVVNTGRVQGDFKVSWMV

ENSGT00720000108445_1_Linker_0_1 (296, 354)

FQAGD
NGEGLGTHPGPKDPSSFQVTFSATRNATHRGAVALDDVEFRDCGLPTPQ---A

PF00057 // ENSGT00720000108445_1_Domain_1 (354, 386)

SCPLGHH
HCQNKVCVESHQLCDGEDNCGDRSD

ENSGT00720000108445_1_Linker_1_2 (386, 398)

EDPLICSHHMAT

PF00629 // ENSGT00720000108445_1_Domain_2 (398, 583)

DFETGLGPWNQL-----------
----------EGWTRNYSAGSMVTPAWPHRDHSRNSAYGFFLISVAKP----GTTAVLFS
PEFQASISDNCSFTFYYYLHGSEASRFQLFLQAQGLNTPQEP-----VLLRSHHGELGTA
WVRDRVDIQSVHPFRI--LLAGKTGP--GGIMGLDDLIMSNSCRLVPDMST--LQSSRS-
---GPEALALSP------QTFIKLPQEACKPGHLSCGE-LCVPPEQLCDFQQQCAEGEDE
QKCGT

PF00629 // ENSGT00720000108445_1_Domain_4 (666, 826)

TDFEST-SAGGWEDISVGKLQWQRLGAQN-GKPAKDA---HQDIPGHFLSLQKAW
GQLRSEARALTPALGPSGPRCELHMAYYFHSHPQGFLALVVVE--NGFRELVWQAPSS-S
SGGWTVEKVLLGARHRPFQLEFVGLVDLDGPGQQRAEVDNVTMRD

ENSGT00720000108445_1_Linker_4_5 (826, 840)

CNPTVTTESDQEVS

PF00629 // ENSGT00720000108445_1_Domain_5 (840, 996)

C
NFERDSCSWHTVHLTDAHWHRVKGHGSEYDHTTGQ---GFFMFLDPTDPPARGQAAVLLT
RPQVPLVPKECLSFWYHLYGPQIGTLHLAMRKDGEEDTLLWSRSGTHGNHWHQAWVTLHH
QLEVNTKYQLLFEGLRNGYHGTMALDDVAVRPGPCWAPRSCSFEDSDCGFSPGGLGLWKR
QGNASG-YVPW--GPWTDHTTETAQ--------GHYMVVDTSPNVLPKGQVASLTSEEHQ
PLTQPACLTFWYHLSLHNP-GTLR--VHVEESTR---RQELSISAHGGFTWRLGSVNVQA
TQAWRVVFEAVAAGVEHSYMALDDLLLRDGPCAQPGS

PF00629 // ENSGT00720000108445_1_Domain_8 (1178, 1345)

CDFESGLCGWSHLAWPSLGGYSW
DWSSGATPS-RYPRPTVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATT--ASCL
HFWYYMGFPEHFYKGKLRVLLSSAQGQLAVWEQGSHLRHQWIQVQIKVSNSEEFQIVFEA
TLGGQPALGPIALDDVQYLAGQHCQKPPSSQGEMAA-P---VSVPVAVGGALLFF-VFLV
-LLGLGSWHWLQK-Q----RCPFQRS-----TDTATSSFDNILFNADQVTL-PESITSSL
--------------------