Query Results 

MAGHLAPDFAFSPPPGGGGEGPAGPEAAAGWVDPRAWLGFQGPPGGPGAGPGAGPGAEVW
GLPPCPPPYDFCGGAAFCGPQVGVGLLPQGGLELAPAEGAAGAEGSPDGASPEPHAADPG
AAKLDKEKLEQNPEEAQDIK

PF00157 // ENSGT00710000106841_0_Domain_0 (141, 212)

ALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS
QTTICRFEALQLSFKNMCKLRPLLQKWVEEA

ENSGT00710000106841_0_Linker_0_1 (212, 232)

DSNENLQEICKTETLLQQAR

PF00046 // ENSGT00710000106841_0_Domain_1 (232, 330)

KRKRTSIEN
RVRGNLESMFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGK-------------
-----------------------------

ENSGT00710000106841_0_Linker_1_3 (330, 426)

RSSSDCPQ--REEFEAAGSPFPGAPGIMDSW
RQTLEPSHTAGMFRPSG---------------------------STRLIPPSHFQARPFP
PVPRL

PF07111 // ENSGT00710000106841_0_Domain_3 (426, 728)

APTWVSDSPPVQSPAHQE--------VPER-RLDNQ--RLQVGMWERA-------
AP-GDGQEPARRDRSLDLQ-------GSQALSQQAELIFRQLQELRRLEEEVRLLRETSL
QQKKRLEAQALELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAELVRKNLEEGSQRELEEVRRL
HQEQLSRLTEAHQ---EALSSLTSKAEGLEK-SLSSLEARKAEDV-EELAMA--RKEAEL
LQKQLSLLRSS---------------------DRIAAQLQQGQ-----RGERMHGA----
--ALAGTWVSARTVRLRQGQRSQRTHGAAPAGAEGSGRGTGVSVHLAQLRQGQRAQRAHG
AAPAGAEGS----ACARRSSGRGRGVSACTAQLRQG--------QG-FSARTAQLQQGQR
GQRTHSAAPAGA-----EGSAHAQRSSGRGRGVS---ACTAQLRQGQRVGGSLSPLGMRR
ARASATVSPSSQVWLLSTVAKVDEAASRIPSLSARLSYATRRVLTIQGLMARKVALAQLR
QE----XPPPPPP---------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSVVA--QQLEQELQRA-------QESLASVGLQLEAARQGQQESTAEAA
SLRHELTQQQEIYGKALQEKVT-EVE---------TRLREQLSETERRLS----EARREH
TKAVVSLRQIQRKSAREKERNQELRHLQDEARKEEGLRLTRRLQELERDKN-LML-----
-----------------ATLRQEGLLSRYKQQRLLAVLPSL--LDKR-TLTPSPRPLGSP
-----------------PTVADSTRESKRG-SLFALLDDLQGLSE---AI----------
--------SREDGPSEADGPSHPLSGCS--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFPPSG---------------------------STGLIPPSHFQTRPLS
TLPK

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLADIPLVQPPGYQD--------VSER-RTDTQ--RPQVTMWERD-------
VA-SNRQEPGQRGRCRELE-------GSQALSQQAELISRQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNMEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRSGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQDDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWVPERQKLLETVQHLQEDRDGLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQMASLQEQVT
AQSQEQAILQRSLQ-DKAAEAEVERMGAKALQLELSRAQEARRWWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLESTMAKVEQAAARLPSLSNRLSYAVRKVHTIQGLMARKLAVAQLR
QE----SCPLPP--PA------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLDVARQGQQESTKEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRKAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LDKKKSVVSSSRPLGCS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICQGHNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------STLIGKDP-----GVMAWWCLDGLPPGLTEPW-KEIWTFG
S--------------RPLHHVPPFSPL-ARSSRDYRNLRR-------------RGNINDW
RQNLESSNNVKMFPSSG---------------------------STGLIPPSHFQARPLS
AVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1401)

MAPNWVSDIPLVQPPTHQD--------VSER-QLDNQ--RPQVATWERN-------
VS-GDRQEPGRRGRSLELE-------GSQALSQQAELISWQLQELRRLEEEARVLRETSL
QQKMRLETQAMELEALA----R------------------AEKASQAEAEGLRAAL----
------------------------------------TGAEVVRKNMEEGSQRELEEVQKL
HQEQLSSLTQAHQ---EALSSLTNKAEGLEK-SLNNLKTKRAEET-KELALA--QSEAEL
LRKQL-----------------------SKTQEDLEAQVILVENLRKYVGERVPPE----
--VHSQAWEPEQQKLLETIRHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCRSLLNRWREKVFALMVQLKAQELEHRDTVKQ-LKGQVAKLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGAKALQMELSRDREAKHRWQQQ-----TAMAEEQ
LRLVTNAVSSSQVWLQSTMAKVEQAATQLPSLSNRLSYAVRKVHTIQGLMARKLALAQLR
QE----SCPPLPSVPV------PDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSQVA--QQLEQELQQT-------QESLASLGLQLEAARQGQEESTEEAA
SLRQELTQQQEIYGKALQEKVT-EVE---------TRLREQLSDTEKRLN----EAQREH
AKAVVSLRQIQHKATREKERNQELRRLQDEARKEEGQRLTRRVQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LAKEKPAESSSRPPGSS
ASIP-------------PEATLSTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEGVCQGDNPKRSVPAPPLSC-----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------LQHSP-----QT------KHIPSLP-----TSRWAIH
S-------------GIPLCCWRAFISC-LINFHSHLPL---------CQVLSRWGNIDGW
RQNLEPSNNVKMFPPSG---------------------------STGLIPPSRFQAWPLS
TLPK

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

IAPTWLADIPLVQPPGHRD--------VSER-RTDTQ--RPQVMMWERD-------
VS-SDRQEPGQRGRCR---------------DQQAELISWQLQELQRLEEKVRLLRETSL
QQKMRLEAQATELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGTEVVRKNLEEGSQRELEEVQRR
HQKQLSSLTLAHQ---EALSSVTSKAEGLEK-SLSSLETRRSGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQDDSEAQVTLVENLRKCVGEQVPPE----
--VHSQTWEPERQKLLETVQHLQEDLDGLHATAELLQVRVQSLTHILALQEEELT---RK
IQPSDSL------KCQSLLNHWREKVFALMVQLKAQELEHSNSVKQ-LKRQVASLQEQVT
AQSQEQAMLQRSLQ-DKAAEAEVEQMGAKALQLELSRAQE------QQ-----TASAEEQ
LRLVVNAVSSSQIWLESTMAKVEQAAARLPNLSNRLSYAVRKVHTIRGLMAQKLAVAQLH
QE----SCPLPPPV--------TDVTLELQQLREERNHLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLAILGLQLDVACQGQQESTKEAA
SLRQELTQQQELCGQALQEKVA-EVE---------TRLWEQLSDTERRLN----EARREH
AKAVVSLSQIQCKAAQEKEWSQELRRLQEEAWKEEGQRLAWRLQELERDKN-CML-----
-------------------------------QRLLAVLPSL--LDKKKSVVSSSRPLGCS
ASVP-------------IAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICQGHNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MASLGSMASR
RWNLDPPAAFGVTQ---------------------------AAGSRELVPPSHFQARPP-
----

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1155)

AAPSWARAGVQL------E--------VLEL-RRENQ--QLRAAMWGWG-------
GGRAAAEDPGSGARFRDQE-------RSQGLSQQAQLVSPQPQELPRLEAEA--------
QQGAKLEAQAEELEAL----------------------------GRAEVEELRASL----
------------------------------------ARAEEARLRLEEGGQQELEAARRQ
HEEEVAHLTQAHL---EALSTLRGQVQELHE-TVQELEARRGQEA-MALAAA--QAEADT
LQEQL-----------------------KKSREELEARDSLVRQLRRHVSEQGVAQ----
--SRCQAWEQERGELQQAVKRLQEERAALSSTSELLQVRVQSLTDILTLQERELA---QK
APNVNILEPESARKARALLSRWREKVFSLMVQLKAQELSHAKHTCQ-LQKEVAELEKEVA
SQRQQEALLLHSLK-GKEAEIQMEQVNSKVLQGELSRSQDSKQQLQDQ-----VQAAEEQ
VQLLSESVHSSQQGLLARMAEVEVALAQLPGLSTRLSYAARQVRILQGLVARKVALAQIR
QEE---SAPAPA--------EAEALDTELRQLREERSRQDAELRFSARLLQQEVARA---
RDQGREERQRLAEAS--QRLERELRES-------REALGEAEARLEAALAGQRDSQDQAA
SLRRELGKQQEVYERGRGGPRAGAAGRGGX------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------RPGPRALVGKDP-----GAMAWWRLDGLPPGLPELW-RELRRLG
S--------------GPLRWGPPPCPP-ARSRRDPRNLRRLK--------RLLGGNVDDW
RQNLELSSTREMLPPSG---------------------------LSGLVPPSHFQARPFP
AQSRAAPPWVSDIPPSQPRAHQD--------VSER----HQ--RPPVTAWEQG-------
VS-GAGHGPCRRGRSLELA-------GSQALSEQAELISRQLQELRRLEEEVRGLRETSL
KQKMRLEAQAVELEALA----R------------------AEKASQVEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGTQRELEEVQRL
HQEQLSSLMQAHQ---EALASLTSKTEGLEK-SLRSLEARRAGEA-KELAEA--LNEAEL
LRKQL-----------------------SKTQEDLEAQVVLVENLRKYVGEQVPPE----
--AGSQAWEPERQELLDTVQRLQEDRAGLHTTAELLQVRVQSLVCVLALQEEELT---RK
LPPSDSLEPECVRKHQSLLSRWREKVFALLVQLRSQELEHRDSPSV-L-HQVAELQEQLI
AQSQERAILQRSLQ-DRAAEVEVERMGTQVLQQELSRAQEARQVAE-------------G
GGSVSCALSSCQIALQSTTAKLEQAVARLPSLGNRLSYAVRKVHTIQGRPGGAASGRG--
-------EPG----------------------------------------KAERAPL---
LRP

PF07111 // ENSGT00710000106841_0_Domain_6 (1084, 1285)

GEEERQQLSKVA--QQLEQELQRA-------QEALAGVGLQLEAARQGQQESTEEAA
SLRQELAQQQETYARALQEKVA-EVE---------TGLREQLSDAERRLN----EARREQ
AKAVVSLRQTQRKAAGEKERNQELRRLQEEARKEEGQRLSRRLQELERDKN-LML-----
-----------------VGTAGAG

ENSGT00710000106841_0_Linker_6_8 (1285, 1347)

LGSPEE------------------------------
------------------P-SGPIPV

PF07111 // ENSGT00710000106841_0_Domain_8 (1347, 1400)

SSPG-SLSLLLDSLQGLSE---AIAEE-------
-----------EAVCQGDSHPRL---------------------SS--------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------PCDSSGSTGLIPPSHFQARSLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWVADIPLVQSPAHQD--------VSER-RLDNL--RPQVPMWERD-------
AS-GDGQEPGRRVRS--LE-------GSQALTQQAELISRQLQELRQFEEEIRLLRETSL
QQKIRLESQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVIRKNLEEGTQRELEEVQRL
HQEQLSCLTVAHQ---EALSSLTSKAEGLEK-SLNNLEARRAEEA-KELATS--QRETEL
LQKQL-----------------------SKTKEDLEAQVTLVENLRKYVGEQVPQE----
--VRSQAWAQERQELLETMQCLQEDRDTLHSTAELLQVRVQSLTYILTLQEEELA---RK
IQPSDSLEPELSKKFQSLLTCWREKVFALMVQLKAQELGHREYAEQ-LKRQVAELEERVA
SQSQEQAILQRSLQ-DKAAELEVERVGAKALQGELSRALEARRQQQQQ-----TALVEEQ
LKLVANSVCSSQIWLQNTMAKVEQAVTRLPSLSNRLSYAARKVHTIQGLVARKVALAQLR
QE----SCPPPPPPPA------TDVSLELQQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERQQLSEVQ--QLEQGAATNP-------KESLASVGLQLEAARQGQ-ESTEEAV
TLRRELTQQQELYGQALQEKVA-EVE---------TRLREQLSETERRLN----EARREH
AKAVVSLRQIQRKAAREKERNQELRQLQDEARREEGLRLTRRLQELERDKN-LML-----
-----------------ATLRQEGLLSRYKQQRLLAVLPSL--LDKGSSAPSAPLE----
-SSS-------------PAVAPSSRDPIKG-SLSALLDDLQGLTE---AI----------
--------AKEEGLCQGDNQNSPAP-----------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1412)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWKQD-------
VS-SDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRQLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSTGARPWASTLTGKDP-----RGMAWWCLDGLPSGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLRMRVKA----LPRILKLSIGWT
WLICEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

IAPTWLSDIPLVQPPGHQD--------VSER-RPDTQ--RPRVTMWERD-------
VS-GDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEDGSQRELEEVQRL
HQEQLSSLTQAHE---EALSSLTSKAEGLEK-SLSSLEARRAGEA-KELAEA--QTEAEL
LRKQL-----------------------SKTQEDLEAQMTLVENLRKYVGAQVPSE----
--VHSQIWELERQKLLETTQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEQVT
SQSQEQAILQQSLQ-DKAAEVEVERMGAKGLQLELSRAQEARHRWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLIARKLALAQLL
G-------------TL------RWMGLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLAWRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLFTVLPSL--LDKKKSVVSSPRPPECS
ASAP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARGSR----DQRNLR---------RRGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
ALRRMAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWEQD-------
VS-NDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLEN

PF07111 // ENSGT00710000106841_0_Domain_2 (799, 1009)

MQ----------------------------------------
---------------------------------------------------VTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVS---------------------------------------

ENSGT00710000106841_0_Linker_2_5 (1009, 1009)

PF07111 // ENSGT00710000106841_0_Domain_5 (1009, 1403)

LTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQELHRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAVQEKERSQELRRLQEEARKEEAQRLAWRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVASSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------X

PF07111 // ENSGT00710000106841_0_Domain_2 (494, 1403)

RSLELG-------VSGALSQQAELISRQLQELRLLEEEVRTLRETSL
QQKMRLESQAVELDALA----V------------------AEKAGQAEAEGLRTAL----
------------------------------------AGAEMVRKNLEEAKQKELEEIQSL
HQEQLSSLTQAHQ---KALDSLTSKAEDLEK-SLNSLEMKQAGEA-KQLTMA--QKEAEL
LRNQL-----------------------SKTQEELEAQVTLVENLRKYVGEQVPPE----
--VPSQARELEQKELLDTLKHLKEDRTNLQATVELLQVRVQSLTHMLALQEEELT---RK
IHPLDPLEPEFPKKCRSLLRGWREKVFALMVQLKAQDLQHRDSTKQ-LRDQVAELQEQVT
AQSQEQAILQRALQ-DKTAQVEVERMSTKTLKMELSQAQEARWRQEQQ-----AASAEEQ
LKFVVSAMNSTQARLQSTMTRVDQAVARIPSLCNRLSYAVRKVHTIKGLMARKLALVQLR
LE----SCPPPEPA----PPPDTDLSLELEQLREERNRLDAELQLSAHLIQQEVGRV---
REQGEAEHRHLTEVA--QQLEQELQRA-------QESLASVGQQLEAARQGQQESTEEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------SRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHKATLEKERNQELRRLQDEARKEEGQRLTRRVQELERDKN-LML-----
-----------------ATLKQEGLLSRYKQQRLLAVLPSG--VSK----KCSSQPVE--
PPES--------------AAASPCKESMKG-SLTVLLDNLQGLSE---AI----------
--------SRDDAICLEDNQNTKSP---PSNPLLG------------RSCQEEE------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGARPWANSLIGNDS-----ESMARWCLDGLPNGSTIPW-RGLWRVG
SLY-------------------CV-QR-VLSCRDRRLLRR-------------KGNTGDW
RQDLEDAYNREMLPPSG---------------------------FAGLVPPSHFQARPLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWASDVPLVQSPASQD--------VLESRRLNAQ--RSTVTTWGQD-------
FC-GDGQGLGQRGRSLELG-------FSGALSQQAELISRQLQELRRLEEEVRSLRETSL
QQKMRLETQAVELDALA----V------------------AEKAGQAEAEGLRTAL----
------------------------------------SGAEMVRKNLEETKQKELEEIQNL
HQEQLSSMTQAHQ---KALDSLTSKAEGLEK-SLNSLETKRAGEA-KQLATA--QKEADM
LRSQL-----------------------SKTQEELEAQVTLVESLRKYVGEQVPPE----
--VPSQEWELERKELLDTLKHLKEDRANLQATVELLQVRVQSLTHMLALQEEELT---RK
IQPLDPLEPEFPKRCRSLLRNWREKVFALMVQLKAQELQHRDSTTQ-LRDQVAELQEQVT
AQSQEQAILQRALQ-DKTAQVEVEQMSTKSLQMELNQAQEARRRQEQQ-----IASAEEQ
LKFVVSAMNSTQAKLQSTMTRMDQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLR
LE----SSPPSEAA----PPLDIDLSVELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERRQLIEVA--QQLEQELQRA-------QESLASVGQQLEAARQSQQESTEEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHKATQAKERNQELRRLQDEARKEEGQRLTRRVQELERDKN-LML-----
-----------------ATLKQEGLLFRYKQQRLLAVLPSG--VNK----KCSPQSVKSL
SPES--------------PAASSCKESVKG-SLTVLLDNLQGLSE---AI----------
--------SRDEDICVEGNQNTKKTKDPATDPLL--------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---ML--------QSSG---------------------------LSGLMPPSHFQTRPPP
GMSRITSVQSPPLPQVLPSSHLG--------HYK

PF07111 // ENSGT00710000106841_0_Domain_2 (455, 1410)

SDHRWEQ--NRLQILREQD-------
GA-GDSDDPKRRTRSLDHV-------GPQSLNSQTELVSQQLEEIWRLEKESQALRLASV
HQKTRLATQAEELEVLG----Q------------------AEQAMQVEIEELRAAL----
------------------------------------AGAELIRQKLEEGNKREMEEIQKL
HKEQISHMTTAHQ---EALAALANKTHELEE-KVKTMESKREEET-KELAVV--QREARM
LREEL-----------------------SKTHAELNTQVALVDQLRKYVGDQISPE----
--SKNQMWEQERKQLLETVQHLQEDRDALCATLELLQVRVQSLQDILVLQEEELG---WK
VQPTDPLKSESAKKAQALLNRWREKVFALMVQLKAQELEHTHHTQK-LKGKVAELEGEVA
SWGQESTILHRSLQ-DKAAEVEVERVNSKVLQGELSRAQDARLWQQQQ-----TETAEEH
MKLVANAVSSSHNWLQDRVAKVAEAVAQLPSLNNRLGYASRQVRTIQGLVARKIALAQLH
QE----QSPPPPP--------SEEMGLELQQLREERNRLDEELQLSARLIQQEVGRA---
REQGEAERIRLNEEA--RQLEQELQKT-------QESLVEVGIQLKAARLSQKESTEEAA
CLRRELTQQQETYGKDLQEKVA-EVE---------SRLREQLLEMERRLN----EARREH
AKAVVSLHQAQCQAARDKERSQELGRLQEEVQREEGFRLRQRLQELERDKN-LML-----
-----------------ATLKQEGLLSQYKQQRLFAILPPL-SLEPGS------EILHPT
KQLL---------KVSTPSHFSPNIHSFSGSYLSALLENLQEMSE---VITRE-------
-----------E---EGDNDSFCPSSGPRRES----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPRLSATRSWASAFIGKDP-----GVMAWWCLNGLPQGLAEPW-RELWRLG
S--------------QPLHSVPPLSPHMCRTSRDSRNLRR-------------RGIMDGW
RQNLEPSDNVEMFRPSG---------------------------STRLIPPSHFQARPLP
TVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1402)

MAPTWVSDIPLVQSLAHQD--------ISER-RLDNQ--RLQVGMWERD-------
AS-GDGQEPARRDXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX----X------------------XXXXXXXXXXXXXXXX----
------------------------------------XXXXXXXXXXXXXXXXXXXXXXXX
XXEQXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXEAGKAKEA-KELVMA--QKENEM
SQRQL-----------------------SKTQEHLEAPGALVENIRK--GEQVPPE----
--VHSQTWKLEGQELLKTLKHLQEDWDALCSTTELLQVQVQNFTYILALEEDLAR-----
-----SWEPESI-REVSLLNCWQEKVFALMMQPKAQDLRHVAELEG-----------RVA
AQN-QEAILQGSLQ-DKAAEVEMEQT---AQQRELRRAQEARCRQQQ------TAVAEEQ
LKLVVNSG-SSQIWA-STMAKVEA-ASQFPSLSNQLSYAAHESHTIQP------------
--------PLP---------PPTKVSLELQQPLEEHSCLVAELQLSPHLIQKEVDQAW--
-----------------ELLEQELQQT-------QESLANMGLQLEVARRGQQESMEEAA
SLWQELTQPQEIYGLVLQENVA-EVE---------TQLRKQPSEMEKRLK----EAWREH
TQA-VSLLQIWHKTAQEKEQNQEHRHLEDEAQKEEGLQLIRLLKELERDQKTVML-----
-----------------AILQQEGLLSHYKQQWLLAVPPPL-LVER--KKESSPRPPGSS
PPSV----------------SLAPSLPAGG-SLCTRLDDLQGLSE---AI----------
--------SRKEDICPEDNLSCFGC-----------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFRPSG---------------------------STGLIPPSHFQARPLP
AMPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1412)

MAPSWVSDIPLA----HRG--------VSER-WPDFQ--RPPGNVWEQD-------
IS-GDGQEPGWRDRSVELQ-------GSQALRQQAELISRQLQEVRRLEEEVRVLQENSL
EQKMKLETQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTRAHQ---EALSSLTSKAEGLEK-SLTGLETSRAGEA-KELAMA--QREAEL
LREQL-----------------------SKTQQDLEAQVTLVEKLRRYVGEQVPPE----
--IHDQAWESERLKLLETVQHLQEDRDGLHTTAELLQVRVQSLTYILSMQEEELA---RK
VQPSDSLEPEFSRKSQALLKHWREKVFALMVQLKAQELEHGACVQQ-LKGQVAEFQERVA
AQSQEQAILQRSLE-DKAAQVEVERMGAKSLQMELSRAQEACRRGQQQ-----TASAEEQ
LKRVAKAINSFQTWIQNPMAEVEQAAARLPSLSSRVSYAVRKVHTIQGLMARKLVLAQLR
QL----SGKLPWKVLELP----------STQVASTLHRGDAPPCLPTEDPQEKCLT---P
RKGGQSCDERLHRPSAPRPSPRSRPRS-------PATLAPLHTPPDTFLRGQCPI-----
--------SLNAIATLMKMYICWTKSNTRFISSFPSGLREGSVLFSWSLATSGQPHTFPC
FPTVVSLGQMQRKATREKERNQELRRLQEEARKEEGLRLTQRLQELQRDKN-LLL-----
-----------------ATLQQEGLLSRYKQQRLLAVL------DKGGSVRPSPRPAGPS
APAP-------------PAAALGPRAATKE-SLSVLLDDLQSLSE---AI----------
--------SKEEAVSQGDNQNSPAARGSECLG----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-----ARGSRDHRNLRRRVKALPRILKGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPSHQD--------VSER-RLDTQ--RPQVTMWKQD-------
VS-SDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEQ-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRG------------
------ACPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGARPWASALIGKDP-----GVMAWWCLDGLPEGLAEPW-RELWRLG
S--------------QPLHCTPPFSPP-TRSGRDCRNLRR-------------RGNIDGW
TESLETSNHVEMFRPSG---------------------------STGLIPPSHFQARPLP
TVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1399)

MAPTWASHIPLVQPPTHRD--------VSER-RPDNQ--RPQVIMWEQN-------
VS-GNGQEPGRRGRSVELE-------GSHALSQQAELISRQLQELRRLEEEVRALRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVKRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLNSLETRRAGEA-KELVVA--QREAAV
LQKQL-----------------------SKTQEDLEAQVTLVENLRRYVGEQVPPE----
--VHSQTWESERQELLETVQHLREDRDGLHTTAELLQVRVQSLVHILAIQEEELT---RQ
VQPSDSLEPEFSRKCQSLLKRWREKVFALMVQLKAQELEHRGHVEQ-LKGQVAELQERAV
AQSQEQAILQRSLQ-DKVAEVEVERMGAKALQVELSRAREAQRRRQQH-----TAAAEEQ
LKLVANSVSSFQTWLQSTVAEVERAVTQLPSLSSRVSYAVRRVHTIQGLMARKLALAQLR
QE----SCPPPLPA--------TDVSLELEQLREERNRLDAEVQLSAHIIQQEVGRA---
REQGDAERQRLSEVA--QQLEQELQRT-------QESLANVGLQLEAARQGQRESTQEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLLETERRLN----EARREH
GKAVVSLRQMQRKATREKERNQELRRLQDEARKEEGLRLTQRLQELERDKN-FML-----
-----------------ATLQQEGLLSRYKQQRLLAVFPSL--LDKGRSVESSPQAPGSS
VPVP-------------PAAAPTTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVSQGDN-----------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLPPSG---------------------------FAGLVPPSHFQARPLP
TQPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1400)

VAPTWISDVTLLPPLDHQD--------VSQR----HQ--RPRVTAWERD-------
VC-GDWHGPGRRGRSLELA-------GSQALSQQAELISRQLQELRRLEEEVRGLRETSL
QQKMRLEAQATELEALA----R------------------AERAGQAEAEGLRTAL----
------------------------------------AGAEAVRKKLEEGSQRELEEVQRL
HQEQLSSLAQAHQ---EALASLTSKAKGLEK-SLSGLEARRAGEA-KELATA--QNEAEL
LRQQL-----------------------SKTQEDLEAQGALVESLRKYVGEQVPPE----
--GRGQAWEPERQELLDAVQHLQEDRASLRATAELLQVRVQSLVHVLALQEEELT---RK
ASPPGSLEPEFVAKHQSLLSRWREKVFALLVQLKSQELEHGDLVKA-LRGQVAELQEQVT
VQSQEQAILQRSLQ-DRAVEVEVERVGVKALQTELGRAQEAQRRQQQQ-----TAVVEEQ
LKLVAGTVSRCQMGFQSTMTKLEQAVARLPGLSNRLSYAARKVHTVQGLMARKLALAQLR
LE----SCPAPTP------PANTSESLELQQLREERNRLGAELQLSARLIQQEVGRA---
REQGEEERQQLSKLA--QQLEQELQRT-------QESLASVGLQLEAARQGQQESTEEAA
SLRQELSQQQEAYARALQEKVA-EVE---------TRLREQLSDAERRLN----EARREQ
AKAVVSLRQMQRTAAREKERNQELRRLQDEARKEEGQRLSRRLQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--VDEGKPVESSSRPPGPP
AAALPTRKSGRGRVAAGPPSGAVLGVCSPG-SLSALLDDLQGLSE---AIAEE-------
-----------DAACQGDSSAVH---------------------S---------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGARPWASALIGKDP-----GVMAWWCLDGLPQGLGEPW-RELWRLG
S--------------RPLHRIPQLSPS-SRNCRDHRNLRR-------------RGGIDGC
TPTLETSNNVEMFRPSG---------------------------STGLIPPSHFQVRPLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1401)

MAPTWASDTPLVQRPTHQD--------VLER-RPDNQ--RPQVTMWEQE-------
VS-GKGQEPEWRGRCTELA-------GSQALSQQAELISRQLRELRRLEEEVRVLRETSL
QQKLRLEAQAVELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAGSLEK-SLNNLETRRSGEA-KELAAA--QREAEL
LRKQL-----------------------IKTQEDLEAQMTLVENLRRYVGEQVPPE----
--VRSQAWESERQELLETVQHLQEDRDSLHTTTELLQVRVQSLTHILCMQEEELA---RK
VQPSDCLEPEFTKKCQSLLKRWREKVFALMVQLKAQELEHRECVER-LKGQVAELQERVE
TQCQEQAILQRSLQ-DKAAEAEVERMGAKALQMELSRVQEARRRRKQQ-----AAPAEEQ
LRLVANAVSSFQTWLQGTVAEVERAAAQLPSLSSRVSYAVRKVHTIRGLMARKVALAQLR
QE----SCPPPPPT--------TDMSLELEQLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERQKLSEVA--QQLEQELQRT-------QESLASLGLQLEAARQGQQESTAEAA
SLRKELTQQQEIYGQALQEKVA-EVE---------GRLREQLSESERRLN----EARREH
TKAVVSLRQIQRKATREKERNQELRRLQDEARKEEGQRLTQRLKELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSP--SDKGVPVEPSPKPSESS
APTP-------------PAAAVCTKESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICEGDSQTSS-SVCL--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSTGARPWASALIGKDP-----RVMAWWCLDGLPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLR--------------RGNIDRW
RQNLEPSNNVKMFPPSG---------------------------STGLIPPSHFQARPLS
TLPK

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLADIPLVQPPGHQD--------ASER-QTDTQ--RPQVTMWEWD-------
VS-SDRQEPGRRSRCRELD-------GSQALSQQAELISRQLQELRRLEEEVQLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVIRKNLEEGSQRELEEAQRL
HQEQLSSLTQAHQ---EALSSLTSKAESLEK-SLSSLETRRSGEA-KELAEA--QREAEV
LRKQL-----------------------SKTQDDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKLLETMQHLQEDRDGLHATAELLQVRVQSLTHILTLQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEQVT
AQSQEQAILQQSLQ-DKAAEAEVERMGAKALQLELSRAHEARRWWQQQ-----TASAEEQ
LRLVVDAVSSSQIWLESTMAKVEQAAAQLPSLSNRLSYAVRKVHTIRGLMARKLAVARLR
QE----SCPLPP--PV------TDESLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLDVARQGQQESTKEAA
NLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRKAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVIPSL--LDKKKSVVSSSRPLGCS
ASVP-------------VAAAVPTKESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICQGHDLDRCSSSNPQKSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLTGKDP-----RVMAWWCLDGLPSGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLRRRVEA----LPRILKGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWERD-------
VS-SDRQEPGRRGRSWGLE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHE---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPSE----
--VHSQTWELERQKLLETMQHLQEDRDSLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEKVT
SQSQEQAILQRSLQ-DKAAEVEVERMGAKGLQLELSRAQEARRRWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLETTMAKVEEAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLR
QE----SCPLPP--PV------ADVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLERELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLTVLPSL--LDKKKSVVSSPRPPECS
ASAP-------------IAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWTHCPGALSGPGAMIGKDP-----EVTAWWCLDGLPQSPGEPW-RELWRLA
R-----------------------------NSRDHRNLPR-----------RVKGKIDGW
RQNLESSNKVEMLPPSG---------------------------FTGLMPPSHFQARPFS
NPPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 841)

MAPTWASDFPTVRSPLHG----------SER-RIDTQ--RPPVTMWEQD-------
LS-VNMQGPGWTGRSVELE-------GSQALSQQAQLISRQLRELRRLEDEVRTLRETSL
QQKMRLETQAMELEALA----Q------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEIIRKNLEEGSQRDLEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-TLNSLESRRAAEA-KELAMA--QKEAEL
LRKQL-----------------------TKTQEDLAAQVTLVENLRKYVGEQVPLE----
--VCHQAWEPERKELLDTVQHLEEERTSLRATTEMLQVRVESLMHMLTLQEEELT---RK
VWFSLGSHHLTL---------------RLLP-----GLPVRPCCN--TCLLVAELQEQVT
VQSQEQAILEGSLR-DKAAEVEVERMGAKSLQIELNRAQEARRRQQQQ-----TALAEEQ
LKLVTSAVSSSQMCFQSNMIKVEQAVARLPSLANRLSYAVRKVHTIRGLMARKLALAQLR
KE----SCPPPLP----PTSVDSDMNLELQQLREERNRLDAELQLSAHLIQQEVGRV---
REQGEAECQQLNKVA--QELEQELQRT-------QESLASVGLQLEAARQSQQESTKEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------SRLREQLSDTERRLN----EARREQ
AKAVVSLRQIQRKATREKERNQELRRLQDEARKEEGERLTRRVQELERDKN-LMM-----
-----------------ATLQQEGLLSHYKQQRLLAVFPSI--LDKK-FVESSPWPLGST
ASAP-------------SATALPTRGSIKG-SLSLLLDNLQGLSE---SI----------
--------SKEEAICEGDKQNSPAPVHG--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------IWPRSSGARPWAGAFTAKDP-----RVMAWWCLDGLPRGLAEPW-REFWRLG
L--------------QPLESIPSMSR----TRRDSRS-------------LRKRGNMDGW
RQNLESLNNAETLRPSG---------------------------YTGLVPPSHFQARSLP
SLPK

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1405)

TAPTWVADTTLVQSSAYQD--------VSER-LLENL--RPQVAIWERN-------
AS-GDGQQPGRRVRP--LE-------TSQALTQQAELISRQLHELRQLEEEVRLLRETSL
QQKMRLESQAMELEAVA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSHRELEEVKRL
HQEQLSCLTAAHQ---EALSALTSKAEDLER-SLNSLEARRAEEA-KELAGS--QRETEL
LQKQL-----------------------SKTKEDLAAQVTLVENLRKYVGDQVPQE----
--VCSQAWELERQQLLETMQRLQEDRDTLCSTAELLQVRVQSLTYILTLQEEELA---RK
IQPSDSLEPELTKKFQSLLTCWREKVFALMVQLKAQELSHRDYAEQ-LKGQXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSRALEARCRQQQQ-----TTVAQEQ
LKLMADSVCSSQIWLQNIMAKVEQSVTRLPSLSNRLSYAARKVHTIQGLVARKVVLAQLR
QE----SCPPPPPA--------PDLSLELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEEERQQLSKVA--QQLEQELQVT-------HESLASVGLQLEAARQVQQESTEEAA
NLRRELTQQQELYGQL-QEKVA-XXX---------XXXXXXXXXXXXXXX----XXXXXX
XXXXVSLRQVQRKAAREKERNQELRQLQDEARREEGLRLTRRLQELERDKN-LML-----
-----------------ATLRQEGLLSRYKQQRLLAVLPSL--LDKGKSVESSPKPPGPS
APSAPLAPS-------SPAVAPSSKDPIKG-SLSALLDDLQGLTE---AI----------
--------VREEALCQGDNQNSCTC-----------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------ILQTSSGAKQYADSLMGREI------SVEWWG-GGDPRGHPEPS--------
-----------------WSCFPPFNSVRAHSPSDHNKKS----------SPKGREKMDGW
RKNLE--------PPST---------------------------FGMFQSSIDLSSRPLP
S

PF07111 // ENSGT00710000106841_0_Domain_2 (422, 1409)

MSSTTSVPSPPLPIVLPSPHHG--------IVDGS-------HRLQILREQD-------
GA-GDSEDPKRRTRSLDYV-------GPQGLNSRTEMISQQLEEIRRLEIESQALRLASV
HQKAHLASQGEELEVLG----Q------------------AKQAMRVEVEELRAAL----
------------------------------------AGAELIRKKLEEGNRQELEETQRV
HKEQISQMTAAHQ---EALATLANKAHELEE-KLKTMESKREKET-KELAVV--QREAKM
LREEL-----------------------SKAHSDLKAQVALVEQLRRYVGDQVPPE----
--SKNQTWEHERKQLLETVHHLQEDRDALCTTLELLQVRVQSLQDILALQEEELG---RK
VQPTDPLESEAARKAQALLSRWREKVFALMVQLKAQELEHTQHTQK-LKGKXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX----XXSHPPP--------LLEIGLELQQLREEKNRLDEELQLSARLIQQEVRRA---
REQGEAERIRLSEEA--RQLEQELQKT-------QESLAEVGIQLKAARLSQKESTEEAA
CLRRELNQQQETYGRDLQEKVA-EVE---------SRLRDQLSELEKRLN----EARREH
AKAVVSLRQAQRQAARDKERSQELGRLQEEAQREEGFRLRQKLQELERDKN-LML-----
-----------------ATLKQEGLLSRYKQQRLFAVLSSP-SLEPGS------GTSQ--
--------------------TLVPKQLLKGSCLSALLDDLQEMSE---VITRE-------
-----------E---EGDN-GRCNCGILLL------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---IS--------SYSG---------------------------LGGLIPPSHFQTRPLP
GMSRMTSVQSPP

PF07111 // ENSGT00710000106841_0_Domain_2 (433, 1396)

LPLILPSSHH----------SNHNHRWEN--HRLQILRQQD-------
GA-GDSEEPKRRGRSLDHV-------GPQHMRSQTEIISQHLEEMRRLEMESQALRVASA
HQKAQLATQAEELEVLG----Q------------------AEQAMRVEVEELRTAL----
------------------------------------AGAELIRQKLEEANKRELEETQKL
HKEQISHMTAAHQ---EVLNTLANKAHELEE-KLKAMESKREEDT-KELTLV--QREATM
LREEL-----------------------SKAHAELETQMALVEQLRRYIGDQFPSE----
--NKNLIWEQERKQLLETVQHLQEDRDTLCATLELLQVRVQSLQDILALQEEELG---QK
VQPTDPLQSEEAKKAQAMLSRWREKVFALMVQLKAQELEHTQHTQK-LKGKVAELEGEVA
SRNQESAILHRSLQ-DKAAEAGVEKANSKMLQGELIRAQDARLWQQQQ-----TKVAEEH
VKLVAHAVNSSHNWLQNRVAKVEEAVSQLPRLNNRLGYATRQIRTIQGLVARKIALAQLH
QE----QSSPAPL--------SEEMGLELQQLKEERKRLDEELQLSARLIQQEVGRA---
REQGEAERIRLNEEA--RQLEQELQKT-------QESLAEVGIQLQAARMSQKESTEEAA
CLRRELTQQQEAYGRALQDKVA-EVE---------TRLREQLSEMERRLN----EARREH
AKAVVSLRQAQRQAVRDKERNQELGRLQEEAQREEGVRLRQRLQELERDKN-LML-----
-----------------ATLKQEGLLSQYKQQRLFAILPSP-SLEPSP------GT----
-----------------SGTLLPTRELLKGSSLSDLLEDLQEMSE---VITRE-------
-----------E---EEGDNGRCSVVGSPSYHT---------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLTGKDP-----RVMAWWCLDGLPSGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLRRRVEA----LPRILKGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 895)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWERD-------
VS-SDRQEPGRRGRSWGLE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHE---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPSE----
--VHSQTWELERQKLLETMQHLQEDRDSLHATVELLQVRVQSLTHILALQEEELT---RK
VQPTDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTALS----
-------------------FLPVERMGAKGLQLELSRAQEARRRWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLETTMAKVEEAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLR
QE----SCPLPP--PV------ADVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLTVLPSL--LDKKKSVVSSPRPPECS
ASAP-------------IAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-AR----GSRDHRNLRR---------RGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGRQD--------VSER-RLDTQ--RPQVTMWKQD-------
VS-SDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEQ-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMHHLQEDRDGLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSREQAILQRSLQ-DKAAEVEVERMGSKGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPNLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLTE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MAWWCLDGLPHGSTTPW-RDLWRLG
P----------------LHCVGALSPP-----RDRRQLQR-------------KGNIDGW
RQNLDPLNNVEMLPPSG---------------------------FAGLVPPSHFQTRPLP
TLPRMAPTWASDIPLVQSTARQD--------VLERREPDEW-------------------
WC-GCRLPAPASALSLEPG-------SSHALSQQAELISRQLQELRRLEEEVRLLRETSL
QQKLRLEAQTMELEALT----V------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEMVRKNLEEESQRELEEIQSL
HQE

PF07111 // ENSGT00710000106841_0_Domain_2 (664, 1403)

QLATA----------------------------------------------QKEAEL
LRKQLRSVGRA--------G-------LFHTQEDLEAQVTLVESLRKYVGEQVPPE----
--VHSQAWEPERQELIDTVQHLEHNRADLQAKVELLEVRVQSLTHMLALQEEELT---RK
IQPADALEPEFPKKCQSLLRRWREKVFVLMVQLKAQDLEHRNSMER-LRDQVAELQEQVT
AQSQKQTLLQHALQ-DKAAEVEVERMSTKAVHMELSRAQEAKRQQQHQ-----MVSAEEQ
LKFVVSAVNSSHISLHSTMTRVDQAIARLPSLSNRLSYAIRKVHTVGGLMARKLALAQLR
LE----SCPPPPPP------PDAELSLELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERRQLKEVA--QQLEQELQQA-------QESLASVGQQLEATRQYQQASTEEAA
SLRQELTQQQEIYRQGVGGKAS-PDT---------PTLSPALL--------------TCS
CLLVVSLRQIQRKATQEKERNQELRRLQDEARKEEGQRLTRRLHELERDKN-LML-----
-----------------ATLQQEGLLFHYKQQRLLSVLPSG--MVK--SLESSPQPPEFS
APGS-------------PAAALRSRESIKG-SLSALLDSLQGLSE---AI----------
--------SKEEAVCQGVNQNT

PF07111 // ENSGT00710000106841_0_Domain_5 (664, 1403)

QLATA----------------------------------------------QKEAELLRKQLRSVGRA--------G-------LFHTQEDLEAQVTLVESLRKYVGEQVPPE------VHSQAWEPERQELIDTVQHLEHNRADLQAKVELLEVRVQSLTHMLALQEEELT---RKIQPADALEPEFPKKCQSLLRRWREKVFVLMVQLKAQDLEHRNSMER-LRDQVAELQEQVTAQSQKQTLLQHALQ-DKAAEVEVERMSTKAVHMELSRAQEAKRQQQHQ-----MVSAEEQLKFVVSAVNSSHISLHSTMTRVDQAIARLPSLSNRLSYAIRKVHTVGGLMARKLALAQLRLE----SCPPPPPP------PDAELSLELEQLREERNRLDAELQLSAHLIQQEVGRA---REQGEAERRQLKEVA--QQLEQELQQA-------QESLASVGQQLEATRQYQQASTEEAASLRQELTQQQEIYRQGVGGKAS-PDT---------PTLSPALL--------------TCSCLLVVSLRQIQRKATQEKERNQELRRLQDEARKEEGQRLTRRLHELERDKN-LML----------------------ATLQQEGLLFHYKQQRLLSVLPSG--MVK--SLESSPQPPEFSAPGS-------------PAAALRSRESIKG-SLSALLDSLQGLSE---AI------------------SKEEAVCQGVNQNTQNTPASVPS-----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGARHWASALIGKDP-----GVMAWWCLDGLPQGLGEPW-RELWRLG
S--------------QPLYYIRPFSPP-SREGRDCRNLRR-------------TGSIDGW
TQTLETSNNVEMFRPSG---------------------------STGLIPPSHFQVRPFP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1412)

MAPRWVSDIPLVQPPAHQD--------VLER-RPDNQ--RPQVTMWGQE-------
VS-GKGQEPGWRGRSVELA-------GSQALSQQAELISRQLRELRRLEEEVRVLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEDVRRL
HQEQLSSLTQAHV---EALSSLTSKAGLVXX-XXXXXXXXXXXXX-XXXXXX--XX-XXX
XXXXX-----------------------XXXXXXXXXXXXXXXXXRRYVGEQVPPE----
--VHSQMWESERQELLETVQHLREDRAGLHTTTELLQVRVQSLTHILCMQEEELA---RR
VQPSDCLEPEFTKKRQSLLKRWREKVFSLMVQLKAQELEHRDRVGQ-LKGQVAELQEGVK
TQCQEQAILQRSLQ-DKAAEVEVERMGAKALQTELSRTQEARRREQQQ-----TATAEEQ
LKLVANAVSSFETWLQGAVAEVTRAAARLPGLSSRVSYAVRKVHTIRGLMARKLALAQLR
QE----SCPRPPPA--------TDMSLELEQLREERNRLDTELQLSAHIIQQEVGRA---
REQGEAERQKLSEVA--QQLEQELQRT-------QESLASLGLQLEAARQGQQESTAEAA
SLRQELTQQQEVYGQALQEKVA-EVE---------TRLREQLSESERRLN----EARREH
TKAVVSLRQIQRKATREKERNQELRRLQDEARKEEGQRLTQRLKELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSP--SDKGLPVESSLRPSESS
APAP-------------PAPALCTKESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICEGDIDL---FFCLSLSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MHTEGRRPGPKRGVGGV-A----------------KGLRGLSSSGKKDGQ
RKNVEPSANEEMLPPSGQWGQARGPLVAFSWETNDHLCSCDSSGFTGLIPPSHFQAKPLP
TLSR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1402)

MAPTWVSDIPQVQPPAHQD--------VSER-RLDIQ--RSPVTTWEQG-------
VS-GNGQGLGRRGRSLEQQ-------GSHALSQQAELIFQQLQELRQLEDEVQVLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------TGAEIVRKKLEEESQQELEEVQRL
HQEQLSSLTQAHQ---EALFSLTNKAEGLEK-SLNSLETRRAMEV-KELTVA--QKEAEL
LRKEL-----------------------SKTQEDLTAQVTLVENLRKYVGEQGPLE----
--TPSQAWETERQELLDTVQNLEEDRDGLHATVELMQVRVQSLMHMLTLQEEELL---RK
VQPSDLLEPEFTKKCQSLLNRWREKVFSLMVQLKAQELEHRDCVKQ-LKGQMAELQEKVT
AQSQEQAILQRALQ-DKTAEVEVERTGAKALQLELSRAQEARRRCQQQ-----AASAEEQ
LKLVAGAVGSSQICFQNTLTKVEQAIARLPSLSNRLSYAVRKVHTIQGLMARKLILAQLR
LE----SCPPPPPPPPPPPPPDIDLNLELEQLREERNRLDSELQLSAHVIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLANLGLQLEAARQSQQESTEEAA
SLRKELTQQQKIYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARKEQ
AKAEVSLRQIQRKATREKERNQELRRLQDEARKEEGQRLTRRVQDLERDKN-IML-----
-----------------ATLQQAGLLSHYKQQRLLAVLPSI--LDKEKSVESSPRPPGS-
-SIP-------------PAAALSSRGPTKE-SLSVLLDSLQGLSE---AI----------
--------SKEEVICQGDNQNSAPVHT---------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------QGNIDGW
RQNLEPSKNVEMFPPSG---------------------------SKGLIPPSHFQARPLS
TSPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1399)

MAPTWMSDISLVPPPAHQD--------ISER-WLDTQ--RSQMTVREQD-------
VS-GDRQEPGWRGRSLELE-------GSQALSQQAALISRQLQELHRLEEEVRVLQETSM
QQNMRLEAQTVELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSKRELEEFQRL
HKEQLSSLTQAHQ---EALSILNNKAEGLEK-SLSSLETRRAGEV-KELAVA--QGEAEQ
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQFPTK----
--GHSQAWEPERQELLKTVQHLQEDRDGLHSTAELLQVRVQSLTHILALQEEELN---RK
VQPSDSLKPEFTRKWQSLLNRWREKVFALMVQLKTQELEHRDSVKQ-LKGQLAELQEQVT
AQSQEQAILQRSLQ-DRATEVEVERMGAKALQMDLSRAQEARRRCQQQ-----TAVAEEQ
LKLVANAVSSSQIWVQSTVAKMEQAAAQLPSLNNRLSYAVRKVHTIQGLMARKLALAQLR
QE----SCPPLPPPPA------TDLSLELQQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERQQLSKVA--QQLELELQQT-------QESLANVGLQLEAARQGQQESTEEAA
SLRQELTQQQEIYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EAWREH
AKAVVSLRQIQHKATREKERNQELRRLQEEARKEEAQRLTRRVQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LDKEKSVESSPRPPV--
-PGP-------------PVAAQPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAILQGDN-----------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLTGKDP-----RVMACWCLDGLPSGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLRR-------------RGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWERD-------
VS-SDRQEPGRRGRSWGLE-------GSQALSQQAEVIVRQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHE---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPSE----
--VHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEKVT
SQSQEQAILQRSLQ-DKAAEVEVERMGAKGLQLELSRAQEARRRWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLTVLPSL--LDKKKSVVSSPRPPECS
ASAP-------------VAAAVPTRESIKG-SLSVLLDDLQDLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----

PF07111 // ENSGT00710000106841_0_Domain_2 (426, 1203)

APSRVADIPLLQLPAHQD--------GSER----HQ--RPRVTAWERD-------
VS-DGDRGPGWRGRSQEQV-------GSQALSQQAELISRQLQEVRRLEEEVRGLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLASLRQAHQ---QALASLTSKAEVLEK-SLSSLEARRAREA-EELATT--QKEAEL
LRGQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--ARSQVWEPERQELLDAVQHLKEDRASLRATAELLQVRVQSLVHMLTLQEEELT---RK
APPPGCLEPEFAVKHQSLLNLWREKVFALLVQLKSQELEHRDSEKL-LRGQVAELQEQVT
AQSQEQAILQRALE-DRAAEVEVERVGAKALHMELNRAQEAQRRQQQQ-----TASAEDQ
LKLVVAIVSSCQMGLQSTMTKLEQAVARLPSLSHRLSYATRKVHTIQGLMARKLALAQLR
LE----SCPAPAP------PADTSQCLELQQLREERNRLGAELQLSARLIQQEVGRA---
REQGEEERQQLSKVA--QQLEQELQCA-------QESLASVGLQLEAARQGQQESMLEAT
SLRQELTQQQETYARALQEKVA-EVE---------ARLREQLSDAERRLK----EARREQ
AKA---------------------------------GRLGRRLQELERDKN-LMLVGTLG
RGCPGAGPRLGWVKVWKATLQQEGLLSRYKQQRLLAVLPTP-PPEEGKPVESSSRPPGAM
AAEPSPRKPGKG-------------------SLAVLLDNLQGLGE---TITK---E----
-----------EAVCQ-------------------------GDSHPRLG-----------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPRSSGSSPWASTLIGKDP-----GVMAWWCLDGLPPGLAEPW-RELWRLG
S-----------------GPLPPFSPP-ARSSRDYRNLRR-------------RGNIDGW
RQNLEPSKNVEMFPPSG---------------------------SMGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1401)

MAPSWVSDIPLVQPPAHQD--------ISER-WRDTQ--RPQVTTRERD-------
VS-GDRQERGWRGRSLELE-------GSQALSQQAELISRQLQELRRLEEEVRALRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSKRELEEVQRL
HQEQLSSLTEAHE---EALSSLTDKAKGLEK-SLSSLEASQAGEA-KELVMA--QGEAEQ
LRKQL-----------------------RKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQAWEPERQELLETVQNLQEDRDGLRATAELLQVRVQSLTHILALQEEELT---RR
VQPSDSLKPEFTRKCQSLLKRWREKVFALMVQLKAQELEHRDSVKQ-LKGQMAELQEQVT
AQSQEQAILQRSLQ-DKATEVEVERMGAKALQMELSRTQEARRRWQQQ-----TAVAEEQ
LRLVANAVSSSQIWVQSTVAKMEQAAARLPSLSNRLSYAVRKVHTIQGLMARKLALAQLR
QE----SCPPRPPPPV------TDLSLELQQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERQQLSKVA--QQLEKELQQT-------QESLASVGLQLETARRGQQESTQEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRKATREKERNQELRRLQEEARKEEAQRLTRRVQELERDKN-LML-----
-----------------ATLRQEGLLSHYKQQRLLAVLPSL--LGKEKAVGSGPRPAGSS
APVT-------------PAAAQPTRESIKG-SLSVLLDDLQDLSE---AI----------
--------SKEEAICQGDNQNCSSSPTTTLSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSTGARPWASALIGKDP-----RVMAWWYLDGLPPGLAEPW-REFWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLRR-------------RGNIDGW
GQNLEPSNNMKMFPPSG---------------------------STGLIPPSHFQARPVS
TLPK

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLADIPLVQPPSHQD--------VSER-RTDTQ--RPQVTMWERD-------
VS-SDRQEPGRRGRCRELE-------GSQALSQQAELISRQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEQAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRLGEA-KELAEA--QREAEL
LRNQL-----------------------SKTQDDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWEPERQKLLETVQHLQEDRDGLHATAELLQVRVQSLTQILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEQVT
TQSQEQAILQRSLQ-DKAAEAEVERMGAKALQLELSRAQEARRWWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLESTMAKVEQAVTRLPSLSNRLSYAVRKVHTIRGLMARKLAVAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLDVARQGQQESTKEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRKAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LDKKKSVVSNGRPLGCS
ASAP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICQGNNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------GTAGGW
RL--QLSEAVEMLPPSG---------------------------FSGLVPPSHFQVRPLP
TQPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1305)

VAPAWVSDPLLLPPPAHQV--------GTER----HQ--RPLVSAWEPD-------
VP-GDWHGPGRRGRSLELV-------GSQALSQQAELISRQLQELRRLEEEVRALRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGHAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRQLEEVQRL
HREQLSSLTQTHQ---EALDSLTSKAQGLEK-SLSGLEARRAGEA-EELAAA--QNEAEL
LRQQL-----------------------SKAQEDLEGQVALVENLRKYVGEQVPPE----
--ARSQAWEPERQELLAAVQHLQEDRASLRATTELLQVRVQSLVHVLTLQEEELT---RK
ALPPGSLEPECAAKHQSLLSRWREKVFALLVQLKSQELEHSDSVKA-LRGQVAELQEQVT
VQSQEQAILQRSLQ-DRAAEVEVERVGAKALQMELGRTQEAQWRQQQQ-----TALAEEQ
LKLVVGAVSSCQIGLQSTVTKLEQAVARLPSLNNRLSYAARKVHTIQGLMARKLALAQLR
LE----SCPAPAPPP--PPPPDTSDSLELQQLREERNRLGAELQLSARLIQQEVGRA---
REQGEEERRQLSKVA--QQLEQELQHA-------QEALASVGLQLEAARQGQQESTEEAA
SLRRELTQQQETYARALQEKVA-EVE---------ARLREQLSDAERRLN----EARREQ
TKAVASLHQMQRTAAREKERNQELRRLQDEARKEEGQRLSRRLQELEREKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPAL--LDEG-------------
-------------------------------SLSALLDNLQGLSE---AIAEE-------
-----------DAAGQGDS-----------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLPPSG---------------------------FTGLVPPSHFQARSLP
TLPRS

PF07111 // ENSGT00710000106841_0_Domain_2 (426, 1401)

APTWASDIPLIQSRTGQD--------VLER-RLDTQ--RPTVTVWEQD-------
VC-GDAQGPGRRGRSLELG-------VSSALSQQAELISWQLQELRRLEEEVRTLRETSL
QQKMRLEAQALELDALA----V------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEMVRKNLEEGNQRDLQEIQSL
HQEQLSSLTEAHE---KALASLTSKAEDLEK-SLSSLEMKRAGET-RQLAAA--QKEVEL
LRSQL-----------------------SKTQGELEAQVALVESLRKYVGEQVPPE----
--VHCQTWEPERKELLDTLQHLREDRADLQATVELLQVRVQSLSHMLALQEEELT---RK
IQPSDALESEFPKKCHLLLRRWRERVFVLMVQLKAQDLEHRNSMKG-LRDQVAELQEQVK
TQSQKQAILQRALQ-DKTAELEMERISTKTLQLELTRAQEGRQRQEQL-----SASAEEQ
LKSVVSAVNSTQTNLHNTMTRVDQAVARIPSLSNRLSYAVRKIHTIKGLVARKLSLAQLR
LE----SCPPPPP------PPDADLCLELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERRQLNEVA--QQLEQELQRA-------QESLASVGQQLEAARQGQQESTEEAA
SLRQELTQQQQIYGQALQEKVV-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHKAIREKERNQELRRLQDEARKEEGQRLARRVQELERDKN-LML-----
-------------------------------QRLLAVLPSG--KEKS-SVGCSARAVESP
EPKC--------------PAAAPSREPPKG-SLTVLFENLQCLSE---AI----------
--------SREEDVCPEDNPSTSPL----LSW----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------VMSPVG---------------------------PRGLIPPSHFQSRSAP
PLAATG---------PAPWTAEP-PSWQPQ

PF07111 // ENSGT00710000106841_0_Domain_2 (451, 1025)

ELTAL-RQENQCLRDALQRWTAGGARAPRG
KAAGEREEPGARTRSLDREAEPPAARHALAISQQAELISHQLQEIRRLEAELTGLRATAL
QQEATAAARESTLACLQGELEQLRGRSQAEGEALRVELEEQKRRGQAEAAALKAELEEQK
RRSLLSPQLSR-------------------------------------------------
----------LHQAHGAEVSSLWQQSLQLEQ-ELSRLHQAHGAELEQEVEAR--RQASQS
LQEQL-----------------------SMAQAELASQQTLLQQLRTYVGEQGSAL----
--G------SERQQLLGQVQRLEGEREALKTTTELLQLRLASLSDVLALQELELS---KK
SQPGDPLQPEPAQKSQSLLSRWREKVFALMVQLRSQELGHTDATKA-LQRQVSELQGEVQ
ARDQKVALLLHPLQ-DKTAEAEMERVKNTTLQAELSHQKDSGQRLQHQ-----AEAAEDR
QQ---VPLGRLHQQIGGQEAELKAAASRLAGLGNRVTFAAKRVDTIQGLVSRKMALARLR
REEQP-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFLSL-ARG----SRDHRNLRR---------RGNIDGW
RQNLEPSNNVEMFPPSD---------------------------STGLIPPSHFQARPLS
TLRR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWEQD-------
VS-NDRQEPGRRGRSWELQ-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAISSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLTARKLALAQLH
QE----SCPLPP--PV------TDMSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTKEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLAWRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLPPSG---------------------------FAGLVPPSHFQARPLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWASDVPLVQSPASQD--------VLE-RRLDAQ--RSTVTTWGQD-------
FC-GDGQGLGRRGRSLELG-------FSSALSQQAELISRQLQELRRLEEEVRSLRETSL
QQKMRLETQAVELDALA----V------------------AEKAGQAEAEGLRTAL----
------------------------------------AGAEMVRKNLEEAKHKELEEIQSL
HQEQLSSLTQAHQ---KALDSLASKAEGLEK-SLNSLETKRAGEA-KQLAMA--QKEADM
LRNQL-----------------------SKTQEELEAQVTLVESLRKYVGEQVLPE----
--FPSQEWELERKELLDTLKHLKEDRADLQATVELLQVRVQSLTHMLALQEEELT---RK
IQPLDPLEPEFPKKCRSLLRNWREKVFALMVQLKAQDLQHRDSTSQ-LRIQVAELQEQVT
SQSQEQAILQRALQ-DKTAQVEVERMSTKSLQMELDQAQEARRRQEQQ-----IASAEEQ
LKFVVGAMNSTQAKLQSTMTRMDQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLR
VE----SSPPSEAA----PPLDTDLSVELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEVERRRLIEVA--QQLEQELQRA-------QESLASVGQQLEAARRGQQESTEEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHKATQEKERNQELRRLQDEARKEEGQRLTRRVQELERDKN-LML-----
-------------------------------QRLLAVLPSG--VNK----KCSPRSVESS
SSES--------------PAAASCKESVKG-SLTVLLDNLQGLSE---AI----------
--------SRDEDICVEDNQNTKKTKNPPSDPLLS-------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGTRPWANSLIGNDS-----EILARWCLDGLPNGPTIPW-QGLWRVG
SLY-------------------CV-QR-VLSCRDRRHLRR-------------KGNRGDW
RQDLQDSYNRKMLPPSG---------------------------FAGLVPPSHFQARPLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWASEVPLVQSPASQD--------VLE-RRLDAQ--RSTVTTWGQD-------
FC-GDGQGLGRRGRSLELG-------FSSALSQQAELISRQLQELRRLEEEVRSLRETSL
QQKMRLETQAVELDALV----V------------------AEKAGQAEAEGLRTAL----
------------------------------------AGAEMVRKNLEEAKHKELEEIQSL
HQEQLSSLTQAHQ---KALDNLASKAEGLEK-SLNSLEAKRAGEA-KQLAMA--QQEADM
LRNQL-----------------------SKTQEELEAQVTLVENLRKYVGEQVLPE----
--VPSQEWELERKELLDTLKHLKEDRADLQATVELLQVRVQSLTHMLALQEEELT---RK
IQPLDPLEPEFPKKCRSLLRNWREKVFALMVQLKAQDLQHRDSTTQ-LRVQVAELQEQVT
SQSQEQAILQRALQ-DKTAQVEVERMSIKSLQMELNQAQEARRRQEQQ-----MASAEEQ
LKFVVGAMNSSQAKLQSTMTRMDQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLR
ME----SSPPSEAA----PPLDTDLSVELEQLREERNRLDAELQLSAHLIQQEVGRA---
RDQGEVERRRLIEVA--QQLEQELQRA-------QESLASVGQQLEAARRGQQESTEEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHKATQEKERNQELRRLQDEARKEEGQRLARRVQELERDKN-LML-----
-----------------ATLKQEGLLFCYKQQRLLAVLPSG--VNK----KCSPRSVESS
SSES--------------PAAASCKESVKG-SLTILLDNLQGLSE---AI----------
--------SRDEDICVEDNQNTKNTKHPPSDPLLS-------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------QPWWPGLGRDP-----GIMAWWRPAGLPPALPEPW-RELWRLG
S--------------GALRWGPSLCPP-ARSPGDPRNRRSRV--------KTLIG-----
-----------TSERSG---------------------------FSGLVPPSHFQARPFP
LQPRVAPTWGSDVPLTQPPAHQV--------VSER----QQ--RPLVAPWEQD-------
VS-GDCRGPGRRGRSLELV-------GSQALSEQAELISRQLQELRRLEEEVRGLRETLL
QQKMRLEAQAVELEALA----W------------------AEKASQVEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLCCLTQAHQ---EALAGLTGRAEGLEK-SLSGMEARRAEEA-KELAAA--RSEADL
LRRQL-----------------------SKTQEDLEAQVALVENLRKYVGEQVPPE----
--AGSQAWEPQRQALLDAVQHLQEDRASLRATAELLQVRVQSLTCVLALQEEELT---RK
LPPSDSLEPECVKKHQSLLSRWREKVFALLVQLRSQELEHRDSQKLPVLHQVAELQEQVT
AQSQERAILHRCLQ-DRAAEVDVERMGAKVGCVEVDGARPCA---REQ-----DPAGEEG
GGSVTCALSSCQIGLQSTTAKLEQAAARLPGLSNRLSYAVRKVHTIQGLMARKLALAQLP
AG----AWGGAAQLP--AAGR---------------------------------------
-----------------------RPCG-------AESLP--------SRQGT--------
-------------------------------------------GASRLAD---

PF07111 // ENSGT00710000106841_0_Domain_7 (1194, 1400)

-RTHRAG
FSTVVSLRQIQRSAAREKERNQELRRLQEEARKEEGQRLSRRLQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL-LDEE-KSAKSSSRPCLP-
---------------------ALPPCWAHR-SLSVLLGNLQGLSE---AIAKE-------
-----------EAVCQGDSQGSPAPVHS--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFRPSG---------------------------STGLIPPSHFQVRPLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1027)

MAPTWASDTPLVQRPTHQD--------VLER-RPDNQ--RPQVTMWEQE-------
VS-GKGQEPEWRGRCTELA-------GSQALSQQAELISRQLRELRRLEEEVRVLRETSL
QQKLRLEAQAVELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAGGLEK-SLNNLETRRSGET-KELAAA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRRYVGEQVPPE----
--VRSQAWESERQELLETVQHLQEDRDSLHTTTELLQVRVQSLTHILCMQEEELA---RK
VQPSDCLEPEFTKKCQSLLKRWREKVFALMVQLKAQELEHRECVER-LKGQVAELQERVE
TQCQEQVILQRSLQ-DKAAEVEVERMGAKALQMELNRTQEARRRRKQQ-----AAPAEEQ
LRLVASAV----------------------------------------------------
-S----SCPPPPPT--------TDMSLELEQLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERQKLSEVA--QQLEQELQRT-------QESLASLGLQLEAARQGQQESTAEAA
SLRKELTQQQEIYGQALQEKVA-EVE---------GRLREQLSESERRLN----EARREH
TKAVVSLRQIQRKATREKERNQELRRLQDEARKEEGQRLTQRLKELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSP--SDKGVPAEPSPKPSESS
APTP-------------PAAALCTKESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICEGDSQTSS-SVCL--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLPPSG---------------------------FAGLVPPSHFQALPHS
TQPRA

PF07111 // ENSGT00710000106841_0_Domain_2 (426, 1318)

APSRVADIPLLQLPAHQD--------VSER----HQ--RPRVTAWERD-------
VS-DGDRGPGWRGRSQEQV-------GSQALSQQAELISRQLQEVRRLEEEVRGLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLASLRQAHQ---QALASLTSKAEVLEK-SLSSLEARRAREA-EELATT--QKEAEL
LRGQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--ARSQVWEPERQELLDAVQHLKEDRASLRATAELLQVRVQSLVHMLALQEEELT---RK
APPPGCLEPEFAVKHQSLLNLWREKVFALLVQLKSQELEHRDSEKL-LRGQVAELQEQVT
AQSQEQAILQRALE-DRAAEVEVERVGAKALHMELNRAQEAQRRQQQQ-----TASAEDQ
LKLVVAIVSSCQMGLQSTMTKLEQAVARLPSLSHRLSYATRKVHTIQGLMARKLALAQLR
LE----SCPAPAP------PADTSQCLELQQLREERNRLGAELQLSARLIQQEVGRA---
REQGEEERQQLSKVA--QQLEQELQCA-------QESLASVGLQLEAARQGQQESMLEAT
SLRQELTQQQETYARALQEKVA-EVE---------ARLREQLSDAERRLK----EARREQ
AKAVVSLRQMQCTAAREKERNQELRRLQEEARKEEGQRLGRRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPTP-PPEEGKPVESSSRPPGAV
AAEPSPRKPGKG-------------------DGLSAG---WGLGA---PAWGALQDPSHL
RSHHPWHLLPRVTGCAARQPAGPRRDHYQGRGCLPGGQPASSCSSPRLGSWGREGPWPGG
WVPR---GGAGEWDGPCCVRFQPLLDLSCAPIKRLQWRGQGTRESGSPQSPPRPLWRGSE
KHLFFLIL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLTGKDP-----RVMAWWCLDGLPSGLAEPW-RELWRWC
S--------------RPLHCVPPFSPL-ARSSRDHRNLRR-------------RGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGHQD--------VSER-QLDTQ--RPQVTMWERD-------
VS-SDRQEPGRRGRSWGLE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHK---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPSE----
--VHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEKVT
SQSQEQAILQQSLQ-DKAAEVEVERMGAKGLQLELSRAQEARCRWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLTVLPSL--LDKKKSVVSSPRPPECS
ASAS-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSSL-ARG----SRDHRNLRR---------RGNIDGW
RQNLEPSNNVEMFPPSD---------------------------STGLIPPSHFQARPLS
TLRR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWEQD-------
VS-NDRQEPGRRGRSWELQ-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRQWQQQ-----TTSAEEQ
LRLVVNAISSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDMSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLAWRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGARPWVSALIGKDP-----GVMAWWCLDGLPQGLGEPW-RELWRLG
S--------------RPLHRIPQLSPS-SRNCRDHRNLRR-------------RGGIDGC
TLTLETSNNVEMFRPSG---------------------------STGLIPPSHFQVRPLP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1402)

MAPTWASDAPLVQRPTHQD--------VLER-RPDNQ--RPQVTMWEQE-------
VS-GKGQEPEWRGRCTELA-------GSQALSQQAELISRQLRELRRLEEEVRVLRETSL
QQKLRLEAQAVELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSGLTSKAGSLEK-SLNNLETRRSGEA-KELAAA--QREAEL
LRKQL-----------------------SKTQEDLEAQMTLVENLRRYVGEQVPPE----
--VHSQAWESERQELLETVQHLQEDRDSLHTTTELLQVRVQSLTHILCMQEEELA---RK
VQPSDCLEPEFTKKCQSLLKRWREKVFALMVQLKAQELEHRECVER-LKGQVAELQERVE
TQCQEQAILQRSLQ-DKAAEAEVERMGAKALQMELSRVQEARRRRKQQ-----AAPAEEQ
LRLVASAVSSFQTWLQGTVAEVERAAAQLPSLSSRVSYAVRKVHTIRGLMARKVALAQLR
QE----SCPPPPPT--------TDMSLELEQLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERQKLSEVA--QQLEQELQRT-------QESLASLGLQLEAARQGQQESTAEAA
SLRKELTQQQEIYGQALQEKVA-EVE---------GRLREQLSESERRLN----EARREH
TKAVVSLRQIQRKATREKERNQELRRLQDEARKEEGQRLTQRLKELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSP--SDKGVPVEPSPKPSESS
APTP-------------PAVAVCTKESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICEGDSQTSS-SVCL--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------ME
KKSLVQPSMFSADKQPG---------------------------LGGLIPPSHFETRRRV
S

PF07111 // ENSGT00710000106841_0_Domain_2 (422, 1401)

VPPPSVSVTSHPPICEPWTDLA------RELVSL-RQANEELRKKQ-------------
----EMEKEVIQSRSLHRQPS----EGTPSESRALEIIAHQIQEIRRLEIALADAHEK--
---------EEQLLKLEQEVKEMDQRQKENVEA-------EQRRHVAKEAAAR------Q
REAELETALQHQKMEAE---------------------------KLRSRV----------
-QELEVELKEDQEQKGQEVVCLKNNL-----------------------QTA--MQEREI
LADQF-----------------------SQSQKALDSQNSLVQQLKTYIGELVPDN----
--KMMEEQNRERMELSNTVQALEKERNVLQTTLSLLQTRLSSLTNILSLQENEIC---KK
GVPQD------YEKFQHLLSRWREKVFCLMVQLKSEEINKEDDHRK-SREKILSLEKALQ
EKDQEQILLLHTLQ-DRTAELEMERVHSKCLLDELSAAKAKSDHLASK-----VEMTDKA
VLNLKQLVDSFVQALSAQEITLKGALSRLVTLGQRVSFASKRVDTTQGLVAQRFALLRLA
KDKGT---RQPSTHCEISQPSYEDLEAEVKLLNEERDRLSAELKRSAHLIESRVAET---
RERLEAEIAEYQQTA--SFLRHSLDENEKSRSELKEQLGVTERELQESCE-------NTA
ELREQLLGTKAEYEKELQRKVN-ELA---------DHHVQQLAQMEKHLN----EARREH
TKAVVALRQSERQMQREKTRNQETLRSLEDASRTREEQLSQQLREAERDKN-LMI-----
-----------------ATLRQEGLLNTYQKNRTAAAQILRTEVEKAHNLNV--KH----
------------------ASLPGSTYCTTE-SISSMVANLQSLGS---TLLDDD------
------------DDQEEED-G---------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLSPSG---------------------------FAGLVPPSHFQARP--
---R

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWASDIPQFQSTFDQD--------VLERRQLDSQ--RPTVTMREQD-------
VY-GDGQGPGQRGRSLELR-------VSGALSQQAELISRQLQELRRLEEEVRMLRETSL
QQKMRLEAQAMEMDALA----V------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEMVRKNLEEGNQRELQEIQTL
HQEQLSSMTQAHE---MALASLTSKAEGLER-ALNSLEMKRAGEI-KQLSVA--QKETEL
LRGQL-----------------------SKTQEELEAQVTLVESLRKYVGEQVPPE----
--VHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELT---RK
IQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKG-LRDQVAELQEQVM
AQSQEQAILQQALQ-DKAAELEVERMSIKTLQMELNRAQEARRRQKQR-----TDSVEEQ
LKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLR
LQ----SCPPPPPA----PPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERLQLNEVA--QQLEQELQRA-------QESLVNVGQQLESALQGQQESTEEAA
NLRQELTQQQQIYGQALQEKVA-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKN-LML-----
-----------------ATLRQEGLLSRYKQQRLLAMLPLG--TDKK-TVRFSPQPEVSP
EHGC--------------PAASPPRECTKE-SLTALFENLQGLSE---AI----------
--------SREEATCPEDKQYTQCPPSDCC------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGPRPWASALIGKDP-----GVMAWWCLDGLPEGLAEPW-RKLWRLG
S--------------QPLHCVPPFSPP-ARKGRGRRNLKK-------------RGNIDGW
TQNLETSDNVEMFQPSG---------------------------STGLIPPSHFQAHPLP
TVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1399)

MAPTWVSDIPLVQTSAHQD--------VSER-RPDNQ--RPQVITWEQD-------
VS-GNGQELGRRGRSVEIE-------GSQALSQQAELISRQLQELRRLEEEVRVLRETSL
QQKMKLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEIKRL
HQEQLLSLTQAHQ---EALSSLTSKAEGLEK-SLNSLETRRAGEA-KELAVA--QREAEL
LQKQL-----------------------SKTEEDLEAQVTLVENLRRYVGEQVPPE----
--VHSQTWESERQELLETVQHLREDRDGLHTTAELLQVRVQSLMHILAMQEEELT---RK
VQPADSLEPEFSRKCQALLKRWREKVFALMVQLKAQELEHRGCVAQ-LKGQVAELQEGAV
AQSQEQAILQRSLQ-DKAAEVEVERMSTKALQLELSRAQEAQRRRQQH-----TATAEEQ
LRLVANFVSSFQTWLQSTMAEVEGAAARLPCLSSRVSYAVRRVHTIRGLMARKLALAQLR
QE----SCPPAPPA--------THMSLELEQLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERQQLSEVA--QQLEQELQRT-------QESLASVGLQLEAARQGQQESTEEAA
NLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLLETERRLN----EARREH
GKAVVSLRQMQRKATWEKERNQELRRLQDEARKEEGLRLTQRLQELERDKN-VML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKGKSVESSPRDPGSS
AAVP--------------LAAPTTRESIKG-SLSVLLSDLQGLSE---AI----------
--------SKEEAISQGGN-----------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------

PF07111 // ENSGT00710000106841_0_Domain_2 (495, 1409)

SLGLQ-------GSQALSQQAELISRQLQELRRLEDEVRVLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLNGLESRRAGEA-KELAAA--QREVEL
LRKQL-----------------------SKTQEDLEAQVTLVESLRKYVGEQAPPE----
--VHSKTWEPERQELLETVQHLQEDRAGLSTATELLQVRVQSLTHILALQEEELT---RK
VQPSDALEPEFTQKCQSLLNRWREKVFTLMVQLKAQELEHRDAVKQ-LEGQVAELQEQVT
VQSQELAILQHSLQ-DRATEVEVERVGAKALQAELSRAQEAQRRQQQQ-----AALAEEQ
LKLVIHVVSSSQVWLQSTVAKMEEAAARLPSLSNRLSYAVRKVHTIQGLMARKLALAQLR
QE----SCPAPPSQL----PPAPDMSLELQQLREERNRLDAELQLSAHLIQQEVGRV---
RXXXXXXXXXXXXXX--XXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXX---------XXXXXXXXXXXXXXX----XXXXXX
XXXXVSLRQVQRKATREKQRDQELRRLQDEARKEEGQRLTRRVQELEKDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--PGKEKSVESSPQPPESS
ASVP-------------PTPAVLTRASLKG-SLSVLLDDLQGLSE---AI----------
--------AKEEAICQGSSNSCCGLLLSRQ------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MDRKKDS
DKQLEPPAAFGVPRSTE---------------------------PRGLIPPSHFQSRSAP
PLPGPV---------GLPWGATSLSNWE---AAEL-KQENQRLKDELQRWRKKGEK----
-----LEEAGNRKRSLDREAEPLSACHTMAMSQQAEIISHQLHEIQRLEAELASLRVASV
QQEAVAVARENTLVNLQGELAELKSQSQAEATALKTELEEVKKGS

PF07111 // ENSGT00710000106841_0_Domain_2 (586, 1401)

RLETEALREELEELR
RRSRLEADSLRQELELAKERHALELGLAQGELQGALEKAEAERKRYEERAQ---EGLQTL
HKEHQTELLRLSEVYGAEVASLKNQVCVLQQ-DLETHH--------KETVQL--REKKDD
LQNQL-----------------------SMAKAELASQNALMLQLKTYVGEQESRQ----
--P-----TSELEHLRNRVQQLEDEKEALKITAELLQVRLASLTDILTLQETELS---KK
VQLQDPLQSDSSQKLQGLLTCWREKVFSLLVQLKSQELSHRNAIKQ-LDWKVKDLEEEVE
SREQKVALLSHSLE-DKTAEANMEQVRNKTLQAEALRSKELAQKLQIR-----AEAAENA
LKGLGDLASRVNQHLLGQEETWKATLSRLAGLGNRVAFAAKRVDTIQGLVCQKIALAKLQ
QEDKV---SI-MKLTEKIQPSYEDLQAELQMLHEERDQLSMELKRGAQLIERKVAEA---
REKVESDLQDLREKS--QSLQEALEAKAMMEQALRQQQEDTERQLEKVCQDLQKSEESEE
GLRHELGQMRAEYEKALQEKVT-EVE---------MQLRKDLSEMEKCLN----EARREH
TQAVVALRQTERQAARDKARSEELAKLQESATQQEVARLEKRMQELERDKN-LLM-----
-----------------VTLKEEGLLAQHKQNRRLAIRGPEES-----------------
------------------TGKTGHKPPSKE-SLFAVLDDLQALGA---AILNEE------
------------EADRDSN-TSAET-----------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPRSSGSRPWA--------------IMAWWCLDGLPPGLAEPW-RELQTLG
S-----------------GPLPPFSPP-ARSSRDYRNLRR-------------KGNIDGW
RQNLECSKNVEMFPPSG---------------------------SMGLIPPSHFQARPLS
TLPRMAPSWVSDIPPVQPPAHQD--------ISER-RRDTQ--RPQVTMREQD-------
VS-GDRQEPGWRGRSLELA-------GSQALSQQAELISRQLQELRRLEDEVRALRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSKRELEEIQRL
HQEQLSSLTQAHQ---EALSSLTNKAKGLEK-SLGSLEARQAGEA-KELAVA--QGEAEQ
LREQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQAWEPERQELLETVQHLQEDRDGLHATAELLQVRVQSLTHILALQEEELT---RR
VQPSDSLKPEFTRKCQSLLKRWREKVFALMVQLKAQELEHRDSVKQ-LKGQVA-LQEQMT
THSQEQAILQRSLQ-DKATEVEVERMGAKALQMELSRAQEARCRWQQQ-----TAVAEEQ
LRLLANVVSSSQIWVQSTVAKMEQAAARLPSLSNRLSYAIRKGSL---------------
----------PP

PF07111 // ENSGT00710000106841_0_Domain_5 (1033, 1401)

PRQD------LTLFFLLQQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERQQLSKVA--QQLEKELQQT-------QESLASVGLQLETARQGQQESTEEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRKATREKERNQELRCLQEEARKEEVQRLTWHVQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LGKEKAVGPSARPPAAS
APPP-------------PAAAQPTRGSVRG-SLSVLLDNLQGLSE---AI----------
--------SKEEAICQGDNQNSPAPVPQQR------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-----ARGSRDHRNLRRRVKALPRILKGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPSHQD--------VSER-RLDTQ--RPQVTMWKQD-------
VS-SDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEQ-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSSGASPWANTLTGKDP-----GVLSWWRLDGLPQGLAEPW-RELWRLG
S--------------PPLHCTSLFSPP-TN-DRDCRNLKRTXXXXXXXXXXXXXXXXXXX
XXX----XXXXXXXXXX---------XXXX--------------XXXXXXX

PF07111 // ENSGT00710000106841_0_Domain_2 (412, 1410)

XXXXXX-XX
XX--XXXXXXXXX------------------XXXX-XXXXX--XXXXXXXXXX-------
XX-XXXXXXXXXXXSMELQ-------GSQALSQQAELISRQLQELRRLEEEVRALRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRTEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLSNKAEGLEK-SLNSLETRRAGEA-KELAVA--QREVEL
LQKQL-----------------------SKTQEELEVQVTLAENLKRYVGEQVPPE----
--VHSQTWELEQQELLETVQHLQEDRDGLHTTAELLQVRVQSLTHILSMQEEELA---RK
VQPSDSLEPEFTRKCQSLLKCWREKVFALMVQLKAQELEHRACVEQ-LKGQVAELQERTA
AQSQEQAILQRSLE-DKAAEVEVERMGAKALQLELSRAQEGGRRRQQQ-----TAMAEEQ
LKLVANAVSSFQTWLQSTMAEVERAAARLPSLSSRASYAVRKVHTIRGLMARKLTLAQLR
QE----SCPPPPPT--------MDVNLELEQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSEVT--QQLEQELQRT-------QESLASVGLQLEAARQGQQESTEEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLLETEKRLN----EARREH
AKAVVSLHQIQRKATREKERNQELRRLQDEAQKEEGLRLTQRLQELERDKN-LML-----
-----------------ATLQQEGLLFRYKQQRLLAVLPSL--LDKGKSVESSPRPSGSS
APLP-------------PAAAL-SRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAISQGDNKLSCSHLPLSS------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFRPSG---------------------------STGLIPPSHFQARPLP
AVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1399)

MAPTWISDIPLVQPLAHQD--------VLER-RPDNQ--RPQVIMWERG-------
VS-GNGQEPRQRGRS--LE-------GSQALSQQAELISRQLQELWRLEEEVRALRETSL
QQKMRLEAQAMELEAVA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTHKAEGLEK-SLNSLETKRAGEA-KELAVA--QREAEL
LRKQLRNRMGRE---------------------------VAKGRCGRYVGEQVPE-----
--VQSRTWESERQELLETVQHLQEDRDGLHTTAELLQVRVQSLTHILSMQEEELA---RK
VQPSDSLEPEFTRKCQSLLKGWREKVFALMVQLKAQELEHRGCKEQ-LKGQVAELQERAA
AQSQEQAILQRSLQ-DKAAEVEVERMGAKALQVELSRVQEAQRRRQQQ-----TAMAEEQ
LKLVANAVSRGAGELSAGVCKAEVGS-PVQVLVFVFSWGTPSTFTPGSLVMTP-TAHFVG
GE----ATPPAPPS-----AVDVGV------LRGIHIKILAQ-CLACCLYSAEVCCSHEA
LLDGSHNSFWFSKVR--SAVDRVLLQY-------QDITAMVLINDFIARKSPRLKTTQTW
FVARFVTSQRHVQGRAGEVRMSWRLG---------SRTALIFATVESRLN-----ERREH
AKAVVSLRQIQRKAVREKERNQELRRLQDEARKEEGLRLTQRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--MEKGKSVESSPRPPESS
APAP-------------PAAAFSTRQATKG-SLCVLLDDLQGLSE---TI----------
--------CKEQAIPQGDN-----------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------GSTGLIPTSHFQSQLFP
ILPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1203)

MAPTWLSDMLLVQLSAHHN--------VSER-WPGNQ--EPQVVLCEWD-------
VS-GDGWERGRRGRSVELP-------GSQALSQQAELISRQLQELRRLEEEVRVLRETSL
QQKMRLESQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLMQAHQ---EALSSLTNKAGGLEK-SLSSLETRRSGEA-KELAAA--QRETEL
LRKQLXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXX----
--XXXXXXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
XXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XX-XXXXXXXXX-XXX
X---XXXXXXXXXX---XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXFQTWFLSTVAEVERATARLPSITARVSYAVRKVHTIQGRRAGKLAVAQLR
QE----SCPPPPAR----------DMSELEQLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERQQLSEVA--KQLEQELQRT-------QESLASLGLQLEAARQGQQESMAEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLSESERRLN----EARREH
AKA---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLTGKDP-----RVMAWWCLDGLPSGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARSSRDHRNLRR-------------RGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLL
TLPRMAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWERD-------
VS-SNRQEPGWRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRTEAEGLRAAL----
------------------------------------AGAEVIRKNLEEGSQRELEEVQRL
HQEQVNAGVERIQIHNGELTLASKQRTGIAEKTLHDDE--TFGEK-KHTWPREMENLCTL
ILIQV-----------------------ALFPQDSGGLPSLEALLPFLVGSSLPLYFTPG
TNSSGVLWR-------AVR

PF07111 // ENSGT00710000106841_0_Domain_2 (800, 1412)

KHLQEDRDSLHATAELLQVRVQSLTHILTLQEEELA---RK
VQPSDSLEPEFTRKCQFLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASIQPIDT
EHASKQIMLTNYIE-TQVVRNKLNRLLKKII-IDGSCAFFVYTRHSKS-----FGNEGRH
GGSVTCALFSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLIARKLALAQLR
QE----SCPLPPPV--------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAV
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSRELRHLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLFRYKQQRLLTVLPSL--LDKKKSVVSSPRPPECS
ASAP-------------VAPAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMS

PF07111 // ENSGT00710000106841_0_Domain_5 (800, 1412)

KHLQEDRDSLHATAELLQVRVQSLTHILTLQEEELA---RKVQPSDSLEPEFTRKCQFLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASIQPIDTEHASKQIMLTNYIE-TQVVRNKLNRLLKKII-IDGSCAFFVYTRHSKS-----FGNEGRHGGSVTCALFSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLIARKLALAQLRQE----SCPLPPPV--------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAVSLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREHAKAVVSLRQIQRRAAQEKERSRELRHLQEEARKEEGQRLARRLQELERDKN-LML----------------------ATLQQEGLLFRYKQQRLLTVLPSL--LDKKKSVVSSPRPPECSASAP-------------VAPAVPTRESIKG-SLSVLLDDLQGLSE---AI------------------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-----ARGSRDHRNLRR---------RGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPGHQD--------VSER-RLDTQ--RPQVTMWKQD-------
VS-SDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEQ-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARHRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLADTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------

PF07111 // ENSGT00710000106841_0_Domain_2 (495, 1411)

SLELG-------GSQALSQQAELISRQLQDLRRLEEEVRVLRETSL
QQKMRLEAQAMELEALA----R------------------AE-AGRAEAEGLRTAL----
------------------------------------AGAEVIRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALASLTQKAEGLEK-SLCSLEARRAGEA-KELAGT--QREAKL
LREQL-----------------------SNTQKDLEAHVTLVENLRKYVGEQVPPE----
--TCSQAWEQEREELLETMQNLQQDRDSLRTTAELLQVRVQSLMHILTLQEEELA---RK
VQPSDSLEPEFTKKCQSLLNRWREKVFDLMVQLKAQELEHRDSVKQ-LKSQVAELQEQVT
TQCQEHAILQRSLQ-DRAAEVEVERMGAKTLKLELSRAQEAKHRRQQQ-----TASVEEQ
LKLVANAISSSQVCLQSTMAKVEQAVARLPSLSNRLSYAVRKVHTVHGLMARKLALAQLR
LE----SCPPPPPAPQ----LIEDTSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSEVA--QQLERELQQT-------QESLASVGLQLEAARQGQQESTQEAA
SLRQELTQQQEVYGQALQEKVA-EVE---------TRLREQLTDTERRLN----EARREH
AKAVVSLRQHCN-TDQEKERKQELRRLQDEARKEEGQRLAQRVQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LNKEKSSECRLRPTGSS
ASTP-------------PAALSCTKTSTKA-SISVLLDNLQGLSE---AI----------
--------AREETVCQGDKPEASSSSSLLNS-----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFRPSG---------------------------STGLIPPSHFQARPLS
TVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1408)

MAPTWASDIF--PAPDHED--------VSKR-LPDNQ--RPPVVVWEQD-------
VS-GTGQKPGWRGXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX----XXXXXXX----X------------------XX-XXXXXXXXXXXXX----
------------------------------------XXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXX---XXX-XXXXXXXXXXX-XXXXX---XXXXX-XXXXXX--XXXXXX
XXXXX---XXX--------X---XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX----
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VQSSDGLEPDFTRKCQSLLQGWRDKVFALMVQLKAQDLEHRALVEQ-LKGQV-DLQEKAT
AQSQEQTILQSSFQ-DRTVVVEVERLGAKALQMELNRAQEAKRRRKQQ-----TAETEEQ
LKLVVSAVNSFQTWLLGTMTEVELAVARLPGLSNRVSYAVRKVHTIQGLMARKMALVQLR
QEREQQSCPPPP--------PDTDMSLELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXX----XXXXX-XXXXXXX
XXX--XX-XXXXXXXXXXXXXX-XXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXVSLRQMQRKAVREKERNQELRRLQDEAWKEEGLRLTQRVRELEKDKN-IML-----
-----------------ATLQQEGLLSRYKQQRLLTVLPSL--LDKETPVESSLEPPGSP
VPVR-------------PEAVLSTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAISQGDNEFCSHLPLS--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MFRPSD---------------------------TTRLIPPSHFQAPP--
---R

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1405)

KTSTWVSNNPLAPSPIHQD--------VLER-RSDNQ--RP-SGMWEQD-------
VS-GDGQEPQRRSRTVDLQ-------GSHALSQQAELISRQLQELRRLEDEVRVLQESSL
QQKLRLEAQSLELEALA----R------------------AEKAGRVEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HREQXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXX-XXXXXX----XXXX
XXXXX----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHVPPE----
--VQSQSWESERQELLETMQHLQEDRDGLRTTAELLQVRVESLLHILSIQEEELA---RK
VQPSDALEPDFTRKCHSLLKNWREKVFALMGQLKAQELEHRAHVQQ-LKAQXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--XX---XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXFQTWLQSTVADVDLALARLPSLSNRISFAVRKVHTIQGLMARKLAXXXXX
XX----XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX---
--XXXXXXXXXXXXX-----XXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXQQQEIYEQALQEKVA-EVE---------TRLREQLLETERRLN----EARREH
AKAVVTLRQMQRKAAREKERNQELRRLHDEAQKEEGLRLTQRVQELEKDKN-IML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LDKGAPPEPSPTPLRPS
ASVP-------------SAATLYTRESIRG-SLSVLLDDLQGLSE---AI----------
--------SKEEAISQGDNQNLCSR-----------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLPPSG---------------------------LSGLVPPSHFQARPFP
AQSRA

PF07111 // ENSGT00710000106841_0_Domain_2 (426, 1071)

APPWVSDIPPSQPRAHQD--------VSER----HQ--RPPVTAWEQG-------
VS-GAGHGPCRRGRSLELA-------GSQALSEQAELISRQLQELRRLEEEVRGLRETSL
KQKMRLEAQAVELEALA----R------------------AEKASQVEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGTQRELEEVQRL
HQEQLSSLMQAHQ---EALASLTSKTEGLEK-SLRSLEARRAGEA-KELAEA--LNEAEL
LRKQL-----------------------SKTQEDLEAQVVLVENLRKYVGEQVPPE----
--AGSQAWEPERQELLDTVQRLQEDRAGLHTTAELLQVRVQSLVCVLALQEEELT---RK
LPPSDSLEPECVRKHQSLLSRWREKVFALLVQLRSQELEHRDSVKA-LQGQVAELQEQLI
AQSQERAILQRSLQ-DRAAEVEVERMGTQVLQQELSRAQEARQRQQQQ-----TARAEEQ
LKLVAGAVCSCQIALQSTTAKLEQAVARLPSLGNRLSYAVRKVHTIQGLMARKLALAELH
LE----SCPPLAPPA--D--------------------------------TEEVGRA---
REQGEEERQQLSKVA--QQLEQELQRA-------QEALAGVGLQLEAARQGQQESTEEAA
SLRQELAQQQETYARALQEKVA-EVE---------TGLREQLSDAERRLN----EARREQ
AKAVVSLRQTQRKAAGEKERNQELRRLQEEARKEEGQRLSRRLQELERDKN-LML-----
-----------------VTLQQEGLLSHYKQQRLLAVLPSL--LDEGRPAESSSRPPGSA
APVLPAAAPST-------------RKSGRG-SLSLLLDSLQGLSE---AIAEE-------
-----------EAVCQGDSQRCP---------------------APVHG-----------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MAWWCLDGLPEGLAEPW-RELWRLG
S--------------QPLHCIPPSSPL-TRTNRDCRNLRR-------------RENIDDW
TQNLETSSDVEMSRPSG---------------------------STGLIPPSHFQARPLP
TLSR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1401)

MAPTWVSDIPLVQPPAHQD--------VSER-RPD-Q--RPQMIMWEQD-------
VS-GNVQEPGRRGRSVELE-------GSQALSQQAELISRQLQELRRLEEEVRVLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRDLEEVKRL
HQEQLSSLTQAHQ---EALSSLTNKAEGLEK-SLNSLETRRAGEA-KELAVA--QKEAEL
LQKQL-----------------------SKTQEDLEAQVTLVENLRRYVGEQVPPE----
--VQSQTWESERQELLETVQHLQEDRDGLHTTMELLQVRVQSLMHILAMQEEELA---RK
VQPSDSLEPEFTRKCQSLLKRWRDKVFALMVQLKAQELEHRGCVEQ-LKGQVAELQERVV
AQSQEQAILQRSLQ-DRAAEVEVERMGAKALQIELNRAQEAQRRRQQH-----TATAEEQ
LKLVANSVSSFQTWLQSTVADMERATTRLPSLSSRVSYAVRRVHTIRGLMARKLAPVQLR
QE----SCPQPPLA--------TDVSLELEQLREERNRLDTELQLSAHIIQREVGQA---
REQGEAERQQLSKVA--QQLEQELQRT-------QESLASVGLQLEAARQGQQESTQEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLLETERRLN----EARREH
GKAVVSLRQMQRKATREKERNQELRRLQDEARKEEGLRLTQRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKGKSVESGPRAPGSL
ARVP-------------PAVAPTSRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVSQGDNQNYPPPVCL--------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPHSTGARPWARALIGKDP-----RVMAWWCLDGLPPD-------------
----------------PLHCVPPFSPL-ARGSRDHRNLRR-------------RGNIAGW
RQNLEPSNNVKMFPPSG---------------------------STGLIPPSHFQARPLS
TLPKT

PF07111 // ENSGT00710000106841_0_Domain_2 (426, 1403)

SPTWLADIPLVQLPGHQD--------VSER-RTDTQ--RPQVTMWERD-------
VS-SDRQEPGRRDRCRELE-------GSQALSQQAELISRQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEK-SLSSLETRRSEEA-KELTEA--QREAEL
LRKQL-----------------------SKTQDDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWEPERQKLLETVQHLQEDRDGLHATAELLQARVQSLTHILALQEEELT---RK
VQSSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVASLQEQVT
AQSQEQAILQQSLQ-DKATEAEVERMGAKALQLELSRAQEARRWWQQQ-----TASAEEQ
LRLVVNAVSSSQIWLESTMAKVEQAAARLPNLSNRLSYAVRKVHTIRGLIARKLAVAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGETERQQLSKVA--QQLEQELQQT-------QESLASLGLQLDVARQGQQESTKEAA
SLRQELTQQQELYGQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRKAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSHYKQQRLLAVLPSL--LDKK-SVVSSSRPLGCS
ASLP-------------VAAAVPSRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAICQGHNLDKCSSSNPQMSS----------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------PSG---------------------------FAGLVPPSHFQARP--
---R

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWASDIPQFQSTFDQD--------VLERRQLDSQ--RPTVTMREQD-------
VY-GDGQGPGQRGRSLELR-------VSGALSQQAELISRQLQELRRLEEEVRMLRETSL
QQKMRLEAQAMEMDALA----V------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEMVRKNLEEGNQRELQEIQTL
HQEQLSSMTQAHE---MALASLTSKAEGLER-ALNSLEMKRAGEI-KQLSVA--QKETEL
LRGQL-----------------------SKTQEELEAQVTLVESLRKYVGEQVPPE----
--VHRQAWEPEREELLDTVQHLREDRADLQATVELLQVRVQSLTHMLALQEEELT---RK
IQPSDVLEPEYPKKCRSLLSSWREKVFVLMVQLKAQDLEHRDSMKG-LRDQVAELQEQVM
AQSQEQAILQQALQ-DKAAELEVERMSIKTLQMELNRAQEARRRQKQR-----TDSVEEQ
LKFVVSAMKSTQDSIHGTMTRLNQTVARIPSLSNRLSYAIRKVHTIKGLMARKVSLAQLR
LQ----SCPPPPPA----PPVDADLSLELEHLREERNRLDAELQLSAHIIQQEVGRA---
REQGEAERLQLNEVA--QQLEQELQRA-------QESLVNVGQQLESARQGQQESTEEAA
NLRQELTQQQQIYGQALQEKVA-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVVSLRQIQHRATREKERNQELRRLQDEARKEEAQRVARRVQELERDKN-LML-----
-------------------------------QRLLAMLPLG--TDKK-TCP--------G
QHGA--------------CSSYPATPSVLE-SLTALFENLQGLSE---AI----------
--------SREEATCPEDKQYTQCPPSDCC------------------------------
------------------------------------------------------------
--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MWPPSSGARPWANALIGNDP-----EIMARWCLDGLPSVPTAPW-REPWRRG
SLR-------------------SRSPP-SLSCRDRRHLRR-------------KGKVRAW
GQDLEASESRAMLPPSG---------------------------FAGLIPPSHFQARPHP
TLPRK

PF07111 // ENSGT00710000106841_0_Domain_2 (426, 1403)

APTWASDIPLAQSSPGQD--------VLQRQPLDSQ--RPTATTWEQD-------
VC-GDGQRPGRRDRSLELG-------VSNALSQQAELISRQLQELRRLEEEVRTLRETSL
QQKMRLEAQAMELDALA----A------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEMVRKNLEEGNQRELQEIQSL
HQEQLSSLTQAHQ---KALASLTSKAEGLEK-SLNSLEVKRAGET-KQLSLA--QKEAEL
LRGQL-----------------------SKTQEELEAQVTLVDSLRKYVGEQVPPE----
--VHRQAWEPERKELLDTVQCLTQERADLQATVELLQVRVQSLTHMLALQEEELT---RK
IQPSDVLESEYPKRCRSLLCRWREKVFVLMVQLKAQDLEHRDSMKG-LRDQVAELQEQVM
AQSQEHAILQRALQ-DKAAELEVERLSTKTLQVELNRAREARRRQEQR-----AASAEEH
LKSLVGAMNSTQENFHSTMTRVNQAVARIPSLSSRLSYAVRKVHTIKGLMARKLSLAQLR
LE----SCPPPPPPPA--RPPDADLSLELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERRQLNEVA--QQLEQELQRA-------QESLASVGQQLEAARQGQQESTEEAA
NLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLSDTKRRLN----EARREQ
AKAVASLRQIQHKATREKERNQELRRLQDEARKEEGQRLARRVQELERDKN-LML-----
-----------------ATLKQEGLLSRYKQQRLLAVLPLG--TDKK-SMGRSPPPVECP
KHES--------------PAAAPSREPMKG-SLTALFENLQGLSE---AI----------
--------SREEAICPEDNQKTQCPPSPLLSR----------------------------
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--------

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----------------------------------------MGGRQQGLVETLLIPAWNFN
HPGAKLPCLLLTLEAVVFQADPPIITP-GLGVQFGVDPRDEARLLLGPQSHITQGNIDGW
RQNLEPSNNVEMFPPSG---------------------------STGLIPPSHFQARPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSDIPLVQPPSHQD--------VSER-RLDTQ--RPQVTTWKQD-------
VS-SDRQEPGRRGRSWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEQ-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATAELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKEQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPSLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLSE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
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----------------------MQKADPPVITPALSVQLCVDSRDEA--------GFLL-
-------------------------GL-QRHITQVRPTAQ-------------AGSIDGC
TQNLETSYNVEMFRPPG---------------------------STGLIPPSHFQARPLP
TVPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1350)

MAPTWVSDIPLVQPPTHHD--------ISER-RPDNK--RPPVMLWEQD-------
VS-GNGKEPGRRGRSVELA-------GSHALSQQAELISRQLQELRRLEEEVRVLRETSL
QQKMRLEAQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVKRL
HQEQLSSLTQAHQ---EALSSLTNKAEGLEK-SLSSLETRRAGEA-KELAVA--QREAEV
LQKQL-----------------------SKAQEDLEAQVTLVENLRRYVGEQVPPE----
--VHRQTWESERQELLETVQHLQEDRDGLHTTAELLQVRVQSLMHILTIQEEELS---RK
VQPSDSLEPEFTRKCQSLLKRWREKVFALMVQLKAQELGHRGCVEQ-LKGQVAELQDQAV
AQSQEQAILQRSLQ-DKAAEVEVERMGAKALQLELSRAQEAQRRRQQH-----AATAEEQ
LKLVANSVSSFQTWLQSTMAEVERATTQLPCLSSRVSYAVRRVHTIQGLMARKLALAQLR
QE----SCPPLLPV--------TDVSLELEQLREERNRLDAELQLSAHIIQKEVGRA---
REQGEAERQQLSEVA--QQLEQELQRT-------QESLASLGLQLEAARQGQKESTEEAA
SLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLLETERRLN----EARREH
GKAVVSLRQMQRKATREKERNQELRRLQDEARKEEGLRLTQRLQELERDKN-FML-----
-----------------ATLQQEGLLSRYKQQRLLAVFPSL--LDKGKSAESSPWAPGSS
LPVP-------------PGAAPISKESIRG-MKGGRPCDYRDDRHLDSVYPQLR-GPG--
--------DSHDAHLEAAGDPGPLPVCRRHLRQWR------------APPSPTHRGWRGG
GLPNIASGAPNPW-----------------------------------------------
--------

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-----------MLPPSG---------------------------FAGLVPPSHFQARPLP
TLPRMAPTWASDIPLVQSRAGQG--------VVER-RLDTQ--RPTVTMWEQD-------
VC-GDGQGTGRRGRSLELG-------VSSALSQQAELISWQLQDLRRLEEEVRSLRETSL
QQKMRLEAQALELDALA----V------------------AEKAGQAEAEGLRAAL----
------------------------------------AGAEMVRKNLEEGSQRELQEMQSL
HQ

PF07111 // ENSGT00710000106841_0_Domain_4 (663, 726)

EQ----------------------------SLSSLEMKRAEET-KQLAVA--QKEVEL
LRSQL

ENSGT00710000106841_0_Linker_4_2 (726, 749)

RSGAGATGKGLAGDGLSRFCLHP

PF07111 // ENSGT00710000106841_0_Domain_2 (749, 1401)

SKTQEELEAQVTLVESLRKYVGEQVPPE----
--VQSQAWELERKELLDTVQRLTEDRTDLQATVELLQVRVQSLMHMLALQEEELT---RK
IQPSDAVEPEFPKKYRSLLRCWREKVFVLLVQLKAQDLEHRNSMKG-LRDQVAELQEQVK
SQSQEQAILHRALQ-DKAAELEVERMSTKTLQMELNRAQEARQRQEQL-----TASAEEQ
LKFLVRAMSSTQANLHSTMTRVNQAVARIPSLSNRLSYAVRKVHTIKGLMARKLSLAQLR
LE----SYPPPPPPP----SLDADLSLELEQLREERNRLDAELQLSAHLIQQEVGRA---
REQGEAERRQLNEVA--QQLEQELRHA-------QESLASVGQQLEAARQGQQESTEEAA
SLRQELTQQQRIYGQALQEKVT-EVE---------TRLREQLSDAKRRLN----EARREQ
AKAVISLRQIQHKAAREKERNQELRRLQDEARKEEGQRLARRVQELERDKN-LML-----
-------------------------------QRLLAVLPSG--MNKK-SAGCSSQLVGSP
DPES--------------PAAAPSGESVKG-SLTVLLDNLQGLSE---AI----------
--------SREEAICQEDVP

PF07111 // ENSGT00710000106841_0_Domain_5 (749, 1401)

SKTQEELEAQVTLVESLRKYVGEQVPPE------VQSQAWELERKELLDTVQRLTEDRTDLQATVELLQVRVQSLMHMLALQEEELT---RKIQPSDAVEPEFPKKYRSLLRCWREKVFVLLVQLKAQDLEHRNSMKG-LRDQVAELQEQVKSQSQEQAILHRALQ-DKAAELEVERMSTKTLQMELNRAQEARQRQEQL-----TASAEEQLKFLVRAMSSTQANLHSTMTRVNQAVARIPSLSNRLSYAVRKVHTIKGLMARKLSLAQLRLE----SYPPPPPPP----SLDADLSLELEQLREERNRLDAELQLSAHLIQQEVGRA---REQGEAERRQLNEVA--QQLEQELRHA-------QESLASVGQQLEAARQGQQESTEEAASLRQELTQQQRIYGQALQEKVT-EVE---------TRLREQLSDAKRRLN----EARREQAKAVISLRQIQHKAAREKERNQELRRLQDEARKEEGQRLARRVQELERDKN-LML------------------------------------QRLLAVLPSG--MNKK-SAGCSSQLVGSPDPES--------------PAAAPSGESVKG-SLTVLLDNLQGLSE---AI------------------SREEAICQEDVPNTTCCPSDPCCG-------------------EEQ------
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--------MWPHSAGARPWASTLIGKDP-----RVMAWWCLDGIPPGLAEPW-RELWRWR
S--------------RPLHCVPPFSPL-ARGSRDHRNLK----------RRVKALNIDGW
RQNLEPSTNNVSGPDQG---------------------------SGGCL------SRPLS
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1403)

MAPTWLSRHSLVQPKAIKM--------S--------R--EPQVPCGKRD-------
VS-RDRA--GPGGESWELE-------GSQALSQQAEVIARQLQELRRLEEEVRLLRETSL
QQKMRLEAQAMELEALA----Q------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEQLSSLTQAHQ---EALSSLTSKAEGLEQ-SLSSLETRRAGEA-KELAEA--QREAEL
LRKQL-----------------------SKTQEDLEAQVTLVENLRKYVGEQVPPE----
--VHSQTWELERQKFLENMQHLQEDRDGLHATVELLQVRVQSLTHILALQEEELT---RK
VQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQ-LKGQVTSLQEQVT
AQSQEQAILQRSLQ-DKAAEVEVERMGSRGLQLELSRAQEARRRWQQQ-----TTSAEEQ
LRLVVNAVSSSQIWLESTMAKVEEAAARLPNLNNRLSYAVRKVHTIRGLTARKLALAQLR
QE----SCPLPP--PV------TDVSLELQQLREERNRLDAELQLSARLIQQEVGRA---
REQGEAERQQLSKVA--QQLEQELQQT-------QESLASLGLQLEVARQGQQESTEEAA
SLRQELTQQQDLYRQALQEKVA-EVE---------TRLREQLSDTERRLN----EARREH
AKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKKKSVVSSPRPPECS
ASVP-------------VAAAVPTRESIKG-SLSVLLDDLQGLTE---AI----------
--------SKEEAVCQGDNLDRCSSSNPQMSS----------------------------
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-----------------------------------MAWWCLDGLPQGLAEPW-RELRRLG
S--------------QPLHRTPSSSPS--RNSRDCRNLRR-------------RENIDDW
TQNLETSDDMEMFRRSG---------------------------STRLIPPSHFQARPHP
TLPR

PF07111 // ENSGT00710000106841_0_Domain_2 (425, 1401)

MAPPWVSDIPLVQPPAHQD--------VLER-LSDNQ--RPQVTMWEKE-------
VS-GKGQEPGWRGRSVELA-------GSQALSQQAELISRQLQELRRLEEEVRVLRETSL
QQKMRLESQAMELEALA----R------------------AEKAGRAEAEGLRAAL----
------------------------------------AGAEVVRKNLEEGSQRELEEVQRL
HQEELSSLTQAHQ---EALSSLTHKAGGLEK-SLSSLETRRSEEA-KELAAA--QREAEL
LRQQL-----------------------SKTQEALEAQVTLAENLRRYVGEQVPPE----
--VHSQTWESERQELLETVQQLQEDRDGLHTTAELLQVRVQSLTHILCIQEEELA---RK
VQPSDCLEPEFTRKCQALLKRWREKVFALMVQLKAQELEHRGCVEQ-LKGQVAELQERAE
TQGQERAILERSLQ-DKAAEVEVERMSAKALQIELSRAQEARRRRQQQ-----TAEAEEQ
LKLVANAVSSFQAWLQSTMAEVERATARLPSLSARLSYAVRKVHTIRGLMARKLALAQLR
QE----SCPPPPPA--------TEMNLELEQLREERNRLDAELQLSAHIIQQEVGRA---
REQGEVERQKLSEVA--QQLEQELQHT-------QESLASLGLQLEAARQGQQESTAEAA
GLRQELTQQQEIYGQALQEKVA-EVE---------TRLREQLSESERRLN----EARREH
TKAVVSLRQMQRKATREKERNQELRRLQEEARKEEGQRLTQRLKELERDKN-LML-----
-----------------ATLQQEGLLSRYKQQRLLAVLPSL--LDKGKPVESGPGNPESS
APAP-------------LAVARCTKESIRG-SLSDLLDDLQGLSE---AI----------
--------SKEEALCEGENQTSSTSVCL--------------------------------
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