ENSGT00710000106527 : Linker Region Query Results

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-----------------------------------------------------TSCQDD-
WIGFLGKCFYFSEN--T---TTWASS---QSFCAS-HAATLAVFNTTK-EL--DFLMRYS
D-----YSQYWIGLSRK-P--GQTWQWIDGT---IYS-----DR-----------FKIIG
IGECAYL---HKT--G------IS-----SASGHL-V--RKWICSKPE------------
--------------------------------

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----------------------------------------MTD-------------GVIY
SML----------------------------------EFPTASQAQNDYRPQQEG----S
--------SD--------------------------------------------------
---------------------------------S----TRASC----------PSCPDL-
WMRYGSRCYYFSVE--K---KDWMSS---REFCLA-KDAHLLVFTDTQ-EM--SLLKDFV
N-----KDFHWIGLRNS-----SGWRWEDGS---ALNHSRILS--------------NSL
VQKCGTI---SKD--G------LQ-----ASSCEV-P--LQWICKKPFA-DR-SLF----
--------------------------------

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-----------------------------------MPAA---------------------
----------------------------------------VAP------------KAST-
CMR---G-------------TK--PT------------STDLLQEGE----MGK------
---KLHGKCLRFI-------STE-----CPVKLYCCYAVI-MVLSVA-VVALSVTLSL--
----------------SVRKEKL------------VNKSPG---------PCCATCPRH-
WIGFGSKCFYFSDD--M---GNWTFS---QTSCMA-QEAHLAQFQSLE-EL--NFLKRYK
G-----PSDHWIGLHRDSP--QHPWMWTNNT---EYN-----NL-----------VPIRG
DGGYAYL---SDG--V------IS-----SGRGY-MN--RKWICSK--CYP-LQGPVILK
PG------------------------------

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---------------------------------------------------------FL-
---------------VT--G-----------KKLHKIS-SECL---------EAACPES-
WIGFQRKCFYFSED--I---KNWTFS---QRFCDS-HGADLVQVETTQ-EL--NFLLRYK
G-----PYDHWIGLSRE-Q--GQPWKWINGT---EWT-----SC-----------FPIRG
GGECAYL---NDK--G------AS-----SARHYT-E--RKWICSKPDTYAQTQRQSS--
--------------------------------

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---------------------------------------------------------YI-
---------HLFTKK---------------------------------------------
---------------VKDVNID----------HESCFYS---FLFF-SGLYFSV------
---------------------------------SRLISSESTK---------AMECSEE-
WIGVRRKCFYFSDD--T---RNWTAS---KRFCSS-HGSELAQIDTPE-DM--KFLKKHA
G-----TSMYWIGLSRK-L--GESWKWTNGT---TFN-----AG-----------FEISG
NGHFAFL---NSD--G------VH-----SSRGFV-D--IKWICSKPIS-----------
--------------------------------

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----------------------------M-TVKEPSPRASEMESERIENR---KV-----
----VEQRIKRPGI-V--TKKMLI----MSSMICGGIAF-----LL-W----AV------
---------------LGFPQK-------SKNPVIFNNKTCSED---------SIICPQS-
WNRINNNCFFQSER--E---KTWMDG---QTKCTA-HSGSLAIFNSKN-EV--ESLMPYL
G----P-SCYWIGLKMDST--SKLWIWTNGD---VFS-----NW-----------FSIDG
SGECACM---FQK--G------IS-----SGNCSD-A--KKYTCSRKGFCP---------
--------------------------------

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----------------------------------------MSS-----------E-NC--
-FI--------------TENS-------------SLHP-----------KSKQES----D
ANSPHFSTQREGF----------FQVPVLCAVV---NVVFITILII-TLIALSVGK----
YN----CPGQYT-----------------------FSVPSDSD---------VSSCLDD-
WVGYQRKCYFISTV--K---KSWTSA---QNACSE-HGATLVVIDSEK-DM--NFLKRYA
G-----RGEHWVGLKKE-P--GQTWKWSDGK---EFN-----NW-----------FNFTG
SEKCVFL---NNT--E------VS-----SMECEK-N--LHWICNKPYK-----------
--------------------------------

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----------------------------------------MEPAREP-------------
---PARTRPPPPA-----ARPA-----------------------PAAPRPRS---PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
MGECVFV---EPT--R------LV-----STECLA-T--RPWVCSKMAYT----------
--------------------------------

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----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----A
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCANC----------PSCPDH-
WMKYGNRCYYFSVE--K---KDWNSS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----DAFRWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-P--LQWVCKKVRP-----------
--------------------------------

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-----------------------------------------------------M------
---------------MTKHK--------K------CFIF---GAAL-II--------I--
-------------------TN---------IFTVCVVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

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----------------------------------MIVVS--AVALI-ALIVLAVALGG--
RR----------NTTVL---------------QIP-RSTCVEN---------LITCPKS-
WLRFHKNCFYLSTE--A---RTWEGS---KSFCAS-LEATLSKITTKQ-EL--DLLKKQV
G-----LFNFWIGLSRK-K--DSIWRWTDDN---VFN-----S---------L--FIITG
GGECAYL---DAS--G------VK-----TASCNQ-P--RRHLCSKAGFCRQKRGGIP-H
TTYGVERERT----------------------

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------------------------------------------------LSSLNWKMGI--
KT----VNSMWDNLITL---------------YLL----QRLE---------QSLAQKH-
WKLVEMKCFSLSSE--T---RDWDSS---QENCKG-HKATLAVVSQK--QL--EILTKGV
G-----NSDYWIGLKKK-F---DQWKWDDNT---TFN-----K---------E--FNIRG
AGNCAYL---DSS--S------VN-----SAGCSQ-P--RRWICSRNLT-----------
--------------------------------

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-----------------------------------------------------K------
---KLQGKCLRII-------SPE-----SPARLHCCYAMI-MVLTA-AVIALSVALSL--
----------------SV-RKSE------------DISIK----------NAHGSCPRN-
WIGFGRKCFYFSED--T---SNWTFS---QNFCME-LKAQLARFDNME-EL--NFLRRYK
G-----TFDYWIGLYRESP--EHPWRWMDNT---EYN-----SS-----------IPIRG
VEDYAYL---NNN--G------IS-----SARIY-AD--RRWICSKPNSYILE-CQIPFA
SS------------------------------

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-----------------------------------MGAA---------------------
----------------------------------------KIE------------EACL-
GML---K-------------ID--LT------------AADCPQEGE----MGK------
---KLQAKCLSVV-------SPA--------KLLCCYRVVIVVLIVA-VVALSVALS---
-----------------VRKEKP------------VMESCE---------PCYATCPSG-
WIGFGSKCFYFSED--V---GNWTFS---QSSCMA-LDSHLALFDSLE-EL--NFLKRYK
G-----PSNHWIGLHRAST--EHPWIWTDNT---KYN-----NM-----------VLTRG
GGECAYL---SES--G------IR-----SGRGY-TR--RKWICNKPNSYT-VQCPLVVD
PG------------------------------

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----------------------------------------MTD-------------SVTY
SIL----------------------------------ALSTAPQAQNDCRPQQTA----S
---------SRS------------------P-LSRYVAVA-LGLL--SVILVS--LLL--
FQ-------------GIMCQG--------FKF-S----TCASC----------PSCPDL-
WVRYGDHCYYFSVE--K---KDWNSS---LEFCLA-KDAHLLMLTDNQQQM--XQLPDFL
T-----QDFYWIGLRNN-----SGWRWEDGS---ALNTSRILS--------------NSL
VQKCGTI---SKE--Y------LQ-----ASSCEV-P--LPWICQKWSF-ADEALF----
--------------------------------

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----------------------------------------QTD-------------SSIY
SFL----------------------------------ESPAAPQVQNDFGEQRRA----P
--------SPRS------------------S-L-SYVAIA-LGLL--TAILMS--VLL--
YQ-------------WILCWD--------SND-S----PCASC----------PSCPDR-
WMKYGDHCYYFSGE--K---KDWNSS---LEFCFA-KDSHLLMLQDSH-EM--SLFKTFL
S-----NDFHWVGLRRK-----SDWRWEDGS---VLNFS---------------------
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------------------------------MINP----E------LRDGRPDGF------
---------RRR--TICNFKPNW--------KICLCVCF---VI---IFAACII------
---------------------------------MIVKWPKCDK---------RVACSGD-
WLAVREKCFYFSDD--T---GNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKKYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYSS-------
--------------------------------

---MVRHRASLEEGMAGAEFP-MEPIQNQAQEQEKLGAPEQQVAGEQQPPLEQPELGKKP
DEHPQGPKEQAAGSPA-TTRNPLGEKPLSLRPTFLRVPQPSLGYGSFRCRGSSSSEQLQG
RGDREGTLALVPVPAP-AESQPREGEPSTPGA--ARDPG-EAGSGAWTPVELQVDVRVKP
VGTAVSGLSPSPLPTTR-----FF--------------S--VTVPDSPAFSRHSSISR--
---SGVSLTPSPGSTWGGSPHPLTNWADRYREQEGRASPGLARS--RESPSELPRCRCR-
-------ELGLGDKEWEKLLPG----CG--ADGDKLHQAIARIG-LPTY-----------
---------MKSL-------RWSLVVMAVL--------L--AMAVI-----TLVVL----
--------------------------------ASRTGMKC-------------QPCPEG-
WMWSEEHCYYHSLE--V---QSWEDS---KAFCSA-HQASLPLLSHSK-----KFLS-SQ
I-----YRLYWVGLYRG----PGGWHWIDGA---PLH-----PQL-LPEEDEG--S--LQ
NRNCGGLE---AG--R------LK-----ALECAS-S--RPWICVREAK-----------
--------------------------------

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---------------------------MV-T--P----E------QHDGRHDNW------
---------KPR--TICKLEKCW--------MLYLCMCI---IL---LIV-VIL------
---------------------------------VIAVFFKCPK---------TVECSGE-
WIGVRRKCFYFSSD--T---KNWTAS---EQFCLS-QGSELAHIDTQE-DM--EFLRRHA
G-----TFMHWIGLNRK-Q--GESWKWTNGT---IFN-----PW-----------FEISG
NGSFAFL---NAD--G------VH-----SSRGFI-D--IKWICSKPQF-----------
--------------------------------

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----------------------------------GLAV------------GLGSG-V--D
GW----VLTRFLL-----S------SDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FPISG
LGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

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---------------------------------------------------IGK------
---TLQRKCAAII-------PPV-----TLAKIYCCFSLI-AVLTA-SVIVLSILLA---
-----------------V-GQAT------------SVLEV----------PVSVGCPKQ-
WIGFGSKCFYFSED--A---RNWTFS---QAFCVS-LEADLVQFETLE-EL--NFLKRYK
G-----PSDHWIGLSRESS--YHIWKWTDDS---EYN-----AS-----------YVIKG
VGECAYL---NDN--G------IS-----SARTY-TD--RKWICSKPN------------
--------------------------------

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----------------------------------------------VE-EL--NFLKRYK
A-----PSNHWIGLRRESS--HHIWRWMDNT---EYN-----NT-----------LAIRG
GGESAFL---NDN--G------V--------RIF-ID--RKWICSKPNSYVCS-CQLCPH
WDPT----------------------------

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----------------------------------------MEPAREPPARTR----PP-P
PA---------AR--------------------------------PPPAAPRPRS-PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFRFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTISG
LGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

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-----------------------------------------------------DLCPSG-
WIEFQRKCYYFSED--E---GNWASS---SLYCSS-HNASLAVIDSQE-EM--KFLLRYK
S-----PPDHWIGLR---------------------------------------------
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---------------MK----------IE-NNNQ--------------------------
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--------------------------------ETDKKKQVSYR---------QSFCPDD-
WIGFQDKCYYFSEN--E---GDWKSS---RDNCTT-AHADLTTIDTDK-EM--SFLHRYK
C-----GSDHWIGLKMT-K--NQTGQWVNGS---IFS-----KW-----------FNVKG
SEECAYL---NDN--G------AG-----TARCYT-E--RKWICRKNIH-----------
--------------------------------

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------------------------------------MLKPPDIQHSLP-LK--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKVHPQ
--------------------------------

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----------------------------------------MEPAREPPARAR----PP-P
PIA-A-RPAPA----------------------------------PAPAAPRPRS-PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

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---------------------PLAVL----SLVLNLI-L---ISVI-IVILST--LI---
-------------------------------------TRPAAP---------LAACPDG-
WVGYRGKCYYFSEP--R---ANWTDS---QKNCSA-HGASLAGIDSQQ-EM--DFLRRNK
G-----SSDHWIGLQKE-P--EQAWKWANGT---EFN-----NW-----------FPIAG
REHCAFL---SGN--N------VA-----STGCRS-S--QPWICSKP-------------
--------------------------------

MERV---WEAARGGQAGAELP-MEPVGSLVPGLEQPQVPEK----ARQPEGPESSPSPS-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPPLSLDYGAC-------PEPP--
------------SPGPASVKLPRNGEAPGA----------EPAPGAWAPMELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQADAAH--
---QLLPRASSLSGTWGRGSTLAAAGTESGRDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--EGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYFSVE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHCWVGAWRG----PQGWHWIDEA---PLP-----PRL-LPEDGKD-----NP
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

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-------------------MHE--TSNVD-KDFIPTELL----------ANPGY------
----LPSEKGSYNSILKRVFVSPLVI---CLS----LTI--VLCGM-VTTALVAT-VK--
F----------------------------------HRKPPECL---------EVACPDN-
WIGFQRKCFYFSFD--T---KNWTSS---QRYCDS-QGADLVQVETSQ-EM--EFLLRYK
G-----PSDHWTGLSRE-R--GQPWKWTNGD---EFT-----GL--------V--SHQRR
RRVCLFE-----------------------------------------------------
--------------------------------

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---------------------------------------------------GDY------
---------------LSSKK-HSININQNRILVILILI----LIFL-ILTVLGLITGLL-
---------------VP--R-----------RKLHKISSSECF---------EAACPES-
WIGFQRKCFYFSDD--I---KNWTFS---QRFCDS-YGADLVQIETLL-EL--NFLLRYK
G-----PYDHWIGLSRD-L--GQPWKWVNGT---EWT-----NC-----------FPIRG
GGECAYL---NDK--G------AS-----SARRYT-E--RKWICSKPDIYAQIKRQNSI-
--------------------------------

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----------------------------------------MSS-----------E-NC--
-FV--------------AENS-------------ALHP-----------ESGQEN----D
ATSPHFSARHEGS----------FKVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSTCSED-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDYEK-DM--NFLKRYA
G-----REEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNITG
SEKCVFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

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----------------------------------------NTSDKCL----QSK------
---KHQGKCLRII-------STE-----PPVKLYCCYVVI-MVLTAA-VIALSVALS---
-----------------VRKEKQ------------VMLTPG---------SCYANCPNG-
WIGFGNKCFYFSEE--Q---RNWTVS---QAYCRA-QAAELARFDSLE-EL--NFLKRCA
S-----YPPHWIGLYRESL--QHPWKWTDNT---EYN-----NL-----------ERVFG
GGLIGTL---YDY--I------IA-----NDFSY-SR--EYWICNKFNSRKVSKHL----
--------------------------------

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----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFHWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-S--LQWVCKKV-T-LF--------
--------------------------------

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------MLCRRGLE--E---NDWNSS---REHCSA-HGASLATIGSAE-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADLYVLWKQKAHPQ
--------------------------------

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------------------------------------------MAVF-IVVAII--IYF--
-------------------VV---------QSCVKTSLPCKCS---------QRFCPDD-
WIGFYNNCYYFSEE--E---RDWNSS---RDSCIS-EHADLTIMDTMK-ER--DFLMRHK
G-----SSDHWIGLKLT-G--IQIGKWVNGA---TFS-----KW-----------FNVSG
NEECAYL---SDG--G------VA-----SARCYA-E--RKWICRKNAH--HLE------
--------------------------------

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---------------------------------------------------IGK------
---DLQRKCLAVL-------SPS-----TLPKVFCYLFIS-AVLTA-GVVALSIVLS---
-----------------V-RQEK------------VVSEP----------SLYAACPKS-
WIGFGNKCFHFSED--T---RNWTFS---QTFCAS-LESNLAQFETVE-EL--NFLKRYK
G-----PSDHWIGLSRESA--QDIWKWTDNT---EYT-----LS-----------FGIRG
VGECAYL---NDN--G------IS-----SARIY-TD--RKWICSKPNTYVSS-CR----
--------------------------------

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----------------------------------------MAD-------------NSIY
STL----------------------------------ELPAAPRVQDDSRWKVKA----V
--------LHRP------------------C-VSYLVMVA-LGLL--TV--ILMSLLL--
YQ-------------RTLCCG--------SKG-F----MCSQC----------SRCPNL-
WMRNGSHCYYFSME--K---RDWNSS---LKFCAD-KGSHLLTFPDNQ-GV--NLFQEYV
G-----EDFYWIGLRDI-----DGWRWEDGP---ALS-LSILS--------------NSV
VQKCGTI---HRC--G------LH-----ASSCEV-A--LQWICEKVLP-----------
--------------------------------

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------------------MEFV-----V----PQKELLG---------AAAVSAA-A--V
T-----KRVWRD------V-SHHF-ADTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

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--------------------------------LLNVV-L---VSVV-IILIII--LAA--
WRVD---------------CP------------GWFSNPEALH---------SAACPED-
WVRYRGKCYYFSEL--E---ATWTDS---QKNCSA-HDASLAGIDSQQ-EM--DFLMRYK
G-----SFDHWIGLQRE-P--GQPWKWANGT---KFN-----NL-----------FLVGG
EEHCAFL---NHN--D------VG-----STGCAE-T--GRWICSKPVQ-----------
--------------------------------

MERV---WEAARGGQAGAELP-MEPVGSLVPGLEQPQVPEK----ARQPEGPESSPSLS-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPPLSLDYGVC-------PEPP--
------------SPGPASVKLPRNGEAPGA----------EPAPGAWAPMELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQGDPAH--
---QLLPRASSLSGTWGRGSTLAAAGTESGCDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELGLEKEDAALLPR----TGL--EGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYFSVE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGKD-----NP
DINCGALD---EG--T------LV-----AANCGT-P--RPWVCAKGTQ-----------
--------------------------------

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-------TTTR----------LLL-G---------AIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ESPCPEE-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FAISG
MGECVFV---EPT--R------LV-----STECLA-T--RPWVCSKMAYT----------
--------------------------------

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-------------------------------------------------------CPHG-
WVGSNGVCYYLSRD--S---RSWEQA---QERCSE-LGASLAILK-DE-AM--DLLFRLR
G-----NVDYWIGLRR--------------------------------------------
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--------------------------------

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-MRDMSEEITLTNSGDFQSTE----------------------------SQEFQ------
----------------TRSKRRFY-PSQVTSLRLMIVVF--LSVIV-ALGASLAVE----
------------------------------------KKKFQTD---------HTRCLDD-
WIGYQQKCFLFSEN--T---TTWKMS---QSFCAS-YQATLAVFNSTK-EL--NFLKRYA
D-----HSHYWIGLSRE-E--GTEWQWADGT---IYN-----S---------R--IKITG
NGQYAYL---HKN--G------IS-----SSSSHL-F--QKWICSK--------------
--------------------------------

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-----------------------------------------MR------------I----
---------S------KVTANT--HSDGK-TDLHFLLCEYVGRRTRA----YGK------
---MFHGKCLRIV-------SPE-----SPAKLYCCYGVI-MVLSV-AVVALSVALSV--
----------------K---MTP------------QISTI----------NTYAACPRN-
WIGVGNKCFYFSEY--A---SNWTFS---QTFCKA-QEAELARFDTEE-EL--NFLSRYK
G-----SFDYWIGLHRESS--EHPWKWTDNT---QYN-----YS-----------LSIRG
VERYAYL---NDI--G------IS-----SARVY-AD--KRWSCSKLNSYSLQ-CKTPFS
PM------------------------------

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-----------------------------------MPSS--AHLQDPPPHLSRTLTQD--
------------------------------------EEQTSLR------------QSSS-
CGP---STT-------SASASE--SLSGS------------TKSRIS----QKK------
---LLEGMLPKII-------PTE-----SAAKLLCCYAVF-MALTV-VVIALSIALSV--
----------------K---KTP------------QISAV----------NTYAACQRN-
WIGFGNKCYYFNET--A---RNWTFS---QTLCKE-QEAELARFDNEE-EL--NFLKRYK
G-----SSGYWIGLHRESS--ADPWKWTDNT---AYN-----NL-----------VPIKG
EEKHGFL---SDN--G------LS-----SGKDY-IK--RKSICSKLNSYTSQ-CP----
--------------------------------

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------------------------------------------------------------
------------------------------------------------------------
---------------------R-----G----PEGQLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEATLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------KRR--TICNFKPNW--------KICLCVCF---VIII-IFAACII------
---------------------------------MIVKWPTCDK---------RVACSGD-
WLAVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYSL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MILKLILS-LK--DFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---KFK-----N---------S--FVTKG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRQKIHEVNVLDNRETK
SK-------IIKDETNKVFFQLNKVEVLYLSG

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-EG--
-SV--------------TENS-------------SSHL-----------ERGERD----H
GTHMYFEKHHEGS----------IQVPIPCAVL---VVVIITSLSI-ALVALLVGQ----
YN----CPGLYT-----------------------NLASSDHP---------VASCEDE-
WLAYRRKCYFFSTT--T---NSWASA---QNSCSQ-EGATLAVIDSRK-DM--IFLKRHA
G-----EQEHWIGLKNE-A--NQTWKWANGQ---DFN-----HW-----------FNITG
SERCASL---NNT--D------IT-----TVDCEA-S--LHWVCSKPFR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MLG--E---NDWNSS---REHCNA-HGASLATIGSAE-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDALWTWSNVT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKVHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------KTATPC---------QCLCPVD-
WVNFQNKCYYFSKE--E---RDWNSS---RSNCST-HRVDLTTIDTEE-EM--RFLSGYK
G-----SYDHWIGLKMT-G--DQSGQWVNGT---KFN-----KW-----------FAVKG
NEECAYL---NDD--G------AA-----TARCYT-E--RRWICRKEIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGE-----------G-DQQ-
-E-------------------------------TFSEHK-------ADVSPPTL------
----C----PPGS-WCYGTGRRRSR--VQLIAVCAALGT--LILVL-VV--ISTGE----
---------------------------------------------------------CQ-
E----GKCYYLSKE--E---NDWNSS---REHCNA-HGASLATIGSED-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQNAHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LKFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFHWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-P--LQWVCKKV-R-P---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AKRE------------PGIEK----------TLYATCPKD-
WIGFGSKCFYFSED--T---RNWTFS---QTSCLS-LEAQLAQFDSLE-EL--KFLRRYK
G-----TSDHWIGLHRESS--QHAWRWTDNT---QYT-----NV-----------TFIRG
AGECAYL---NDN--G------IS-----SARVY-TD--RKWICSKSNSFPLQ-GPRVLN
PF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MQTDTSPRLP------------QTS-----
----HERRHHRLMF-D--AKKVLT----LWTLLGGAVAV-----LL-W----GF------
---------------FSFPRK-------FTVTRAARNKTCDDE---------VKLCPKD-
WNKLRQNCFSRIQH--K---NSWLTA---NDTCEL-HDATLAVFIDKT-EV--EILMNQI
Q----EMKTYWIGLHRQNL--LGIWVWTNGS---KYN-----DL-----------HDIQD
HGQCAFV---HQK--G------ID-----STSCED-Q--KEFICTREGHCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MQTESSLRLS------------QS------
-------SHHRLTF-D--LKKVVT----LWILVIGVIAV-----LL-W----GF------
---------------FSFPKK-------FTVTRQTKNEVCSDG---------VKICLHG-
WNKLNRNCFTHFSH--A---NSWFTA---KETCKF-HDATLAVFNDQT-EL--DIVMKQM
E----DIQTFWIGLYKKDF--RGPWVWTNGS---KYN-----NW-----------YEVQD
YGHCAFL---HKS--G------ID-----STNCND-L--KEYICTQEGHCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FV--------------AENS-------------SLHP-----------ESGQEN----D
ATSPHFSTRHEGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSED-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSEK-DM--NFLKRYT
G-----REEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNVTG
SEKCVFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MGLVVG-W--Q
W-----DRRWDVE-----P-LSLL-LDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FNIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------NFLR-RYKGTFDYWIGLY--RESPEH-P-----WRWMDN
TE----------------------------------YNSSYVL-----------------
-------------------------------KIDF---S--HIY-IL----TGK------
---KLQENIFRIV-------SPV-----SPAGLYCCYAVI-IVLTG-AVIALSVALSL--
----------------K----PE------------QVSVK----------TTYNTCPRN-
WTGFGSKCFYFSED--I---STWTFS---QNFCME-LKAQLAGFDNME-EL--NFLRRHT
V-----NFDYWIGLHRESP--EHPWRWMNDT---EYN-----SS-----------VPIRG
VEKHAYL---KNN--K------IS-----SARIY-AE--KRWICSKTNNCILQ-CQIPCA
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MATVQPGE------
----EEVRAQRGS-GCSELRQNRRR--VLCVA---VLCI--LVLAL-VAVI---VL----
--------------------------------QRPSCPPPPPF---------SHVCPNA-
WVGFQGKCYYFSYT--K---SDWNSS---REQCHR-LGASLATVDTEE-EM--GFILQYH
S-----PEDHWIGLHRA-E-GDEHWTWADGS---AFS-----N---------W--FELRG
GGQCVYL---NGD--R------IN-----STLCHS-E--KFWVCSRADSYVLWWKGTNPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DG--
-SV--------------TENS-------------SSHL-----------ERGEKD----H
GTSSYLQNSHEGS----------IQVPIPWAVL---IVVVITSLII-ALVALSVGQ----
YN----CPGLYY-----------------------HLASSDYR---------VASCKDE-
WVAYQRKCYFFSTT--T---NSWASA---QNSCSQ-EGATLAVIDSQK-DM--IFLKRHA
G-----EQEHWIGLKNE-A--NQTWKWANGK---EFN-----SW-----------FNMTG
SESCASL---NNT--D------IT-----TEDCEA-S--LHWVCSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MILKLILS-LK--DFLRRYK
C-----SSDHWIGLKMA----NGTGQWVDGA---KLK-----KS-----------FAVKG
SEGCAYL---SDD--D------PA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MC--LLAPEI-LFTVPLRKKMAA
VE----------------------------------VAEGMLK-----------------
------------------------------TDLTL---RDGMEEGGE----SGK------
---GLQRKCLRIK-------SPI-----TDIKLYCCYFII-AVLTI-SVVALSVVLS---
-----------------V-REEK------------VPLEH----------SVYAACPES-
WIGFGSKCFYFSED--T---RNWTFS---QTFCTS-LEAHLAQFQTPE-EL--DFLKRYK
G-----PSDHWIGLYRKSA--RQSWKWTDNT---EYN-----TS-----------FAIRG
VGECAYL---NDN--G------IS-----SARNY-TD--RKWICSKPNSYVYG-CQ-MRS
PIKYGP--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-NG--
-FV--------------TENS------------SSVHL-----------ERGQND----N
APSVHFQTHHEGS----------LGVPIPCAVM---SVVFITILVI-TLIALSVGQ----
YN----CPGQYE-----------------------LGMPLDSP---------VSLCSAD-
WVGYQGKCYLFSAK--T---ENWMSA---YMACNK-HGATLAVIDSEK-DM--IFLKRYA
G-----GNEHWIGLRYE-A--NQTWKWSNGR---EFS-----NW-----------FNFAK
SENCAFL---NST--E------VS-----STDCEK-E--LHWICSKPSP-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MEELIQ
S-----PSNHWIGLRRESS--HHIWKWMDNT---EYN-----NT-----------LAIRG
GRECAFL---NDN--G------V--------RIF-ID--RKRICSKPNSYVCS-CQLCPH
WDPT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------NISPLL---SHAY-IC--IYT------
---------------------------------YIFMCLKHAK---------PVVCSED-
WVGVRDKCFYFSDD--T---RNWTAS---KMFCSL-QKSELAQIDTQK-DM--EFLKRFA
G-----TDMYWIGLSRK-P--EDSWKWTNGS---TFN-----NW-----------FQITG
NGSYAFL---SAD--G------VH-----SSRGLI-D--IKWICSKCK------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------M---GNWTFS---QSSYMA-LDAHLALFDSLE-EL--NFLKRYK
G-----ASDHWIGLHREST--EHPWIWTDNT---EYN-----NL-----------VLT--
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------K------
---TLQGKCLRVV-------SPE-----YPAKLHCCYGVI-MVLTG-AVVALSVALSV--
----------------R---TTE------------QISIKN---------NTYSACPRK-
WIGFGNKCFYFSEY--S---SNWTFA---QAFCMA-QEAQLARFDNLE-EL--NFLMRFK
G-----NFDCWIGLHRESL--EHPWKWTDNT---EYN-----NX-----------ISIRG
VERCAYL---NNN--G------IS-----SARIY-AD--RSWICSKLNSYSLH-CQTPLF
PF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MTA
AE----------------------------------TSQKMLK-----------------
------------------------------IDLTF---RDGLEE-RE----SGK------
---TLQRKCLALL-------SPV-----TPLKVYCCLFIA-AVLTT-SVVALSIVLSV--
----------------LA-RKEK------------PVIES----------PKYAACPKS-
WIGFGSKCFYFSED--T---RNWTFS---QVFCVS-LEASLAQFATVE-EL--NFLKRYK
G-----PSEHWIGLRRESS--DRIWRWTDNT---EHN-----NT-----------FPIRG
VGECAYL---NDN--G------VG-----SASIY-TD--RKWICSKPNSYVYS-CQ-IRN
SLQNFPMDAS----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------F-FFFFFSV------
---------------------------------LCLISSESAK---------AMECSEE-
WIGVRRKCFYFSDD--T---RNWTAS---KRFCNS-QGSELAQIDTPE-DM--KFLKKHA
G-----TSMYWIGLSRK-L--GESWKWTNGT---TFN-----AG-----------FEISG
NGPFAFL---NSD--G------VH-----SSRGFV-D--IKWICSKPISKT---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-DC--
-SI--------------TENS-------------SSHL-----------ERGQKD----H
GTSIHFEKHHEGS----------IQVSIPLAVL---IVVFITSLII-TLVALNVGK----
YN----CPGLYE-----------------------KLESSDHH---------VATCKNE-
WISYKRKCYFFSTT--T---KSWALA---QHSCSE-DGATLAVIDSEK-DM--TFLKRYS
G-----ELEHWIGLKNE-A--NQTWKWASGK---EFN-----SW-----------FNLTG
SGRCASV---NHK--D------VA-----AVDCEA-N--LHWVCSKPFR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGQ-----------A-AS--
------------------------------------------------SREGSK------
---S--SKSLNGG-YYRKPGHHC--YYRTCTIIL-GVVS--LGLLI-TVAVQAVFLKR--
TSLDVRSFFATCSPDAPFPPS---------SEPLFASFPDSHA---------VPYCPER-
WVGYGGKCYYFSTE--E---KSWDAS---QRFCSS-FNASLAGIDTQQ-EK--DFIMRYA
G-----LVEHWIGLRRE-S--GQPWKWVNGT---QLS-----Q-Q-------L--FEVRA
EGDCAYV---SDI--F------VS-----SSRCYS-V--RNWICSKPDAYT-KAKEDAME
EDLSWQNERLMSKMDNRR--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------S-----
-------------------------NNVE-KDITPSEL----------PANPGC------
---------------LHSKE-HSIKATLIWRLFFLIMF----L----TIIVCG----MV-
---------------A----------GLSAIRANCHQEPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARHYT-E--RKWICSKSDIHV---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SKN---
---------------------------VE-KDIA----P------SELPANPGY------
---------------RHSKEHSS-----KATLIWPLFFL---IMFL-TIIVCGVVV-F--
-------------------SA---------IRANCHQKSSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDAALAQIESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------LVIKE
DGANLYV---AKASQV------LQMNPTPVMVSYP-G--SRRMCLFE-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPVREPPRRSR----PP-P
PPA------PAAA--------------------------------AAASLPRVLS-PGD-
------------------GEGR-----G----QEVLLR------------RSGSG-Y--E
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------DAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEASLTVIQSQK-EL--EFMFKFT
R------KEPWIGLRRV----GDEFHWVNGD---PFH-----P-------D-E--FSVSG
HGECVFV---EPT--R------LV-----TSDCLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREP-------------
---PARARPPPPA-----ARPA-----------------------PAAPRPRS---PAE-
------------------AEAR----------PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
MGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MQTR-----------E-EL--
-SG--------------KENS-------------PLNM-----------ERDIEN----Q
TKSSVMATESDGS----------LQVPIPCAVL---SVVIIVTLII-AIISLSVGQ----
YN----CPGKYVQ---------------ENISPLMTSMPLDLP---------VSTCPDS-
WIGYQGKCYIFSST--T---GSWSTS---QNACSS-YNSTLAQIDSEE-DL--IFLKRYA
G-----NVEHWIGLRNK-T--GQSWQWTDGT---EFS-----GW-----------FTFRG
SGNCVSL---RNT--E------VS-----SVKCQK-E--LHWICSKHTKH----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------SCQED-
WIGFGNQCYYFSDD--I---RNWTSS---QDFCAS-FGANLVKFDSKE-EL--NFLERHR
I-----SYDHWIGLRRKSP--QHSWKWADNT---EFN-----NL-----------AEVRG
TGECAYL---NGV--G------IS-----SGRFY-TE--RKWICSK--------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SA--------------TETS-------------SLHL-----------KRAQQN----N
ATRLHFAAYHEGS----------IQVPIPCAVV---NVVFITTLII-ALVALSVGQ----
YN----CPGQYM-----------------------SSVSPNTH---------VSSCSDD-
WIVYQGKCYLISKK--T---RNWTLA---QNFCSK-HGATLAVIDSEE-DM--IFLKQHV
G-----RTEHWIGLKNE-A--DQMWKWSNGK---KFN-----N-----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------ME-----------------
--------------------------DGR-SD---------------------K------
---DLRKICLAII-------SPV-----TPTKLCCCILII-FILVALNVVTFSTLLAV--
--------------------RSR------------ETDLQ----------VLYVTCPKG-
WIGFGNKCFYFSEE--S---ENWTLS---QISCTS-LEAVLAQFETEE-EL--NFLKRYK
G-----PSDHWIGLSRESS--HHAWKWTDNS---KYN-----AS-----------FIITG
DGERGYL---NDL--G------IS-----SARSY-TD--RKWICSKQITSPCP-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MT----------------------------------TTEVSLK-----------------
--------------------------ILE-TDPTY---RANM-EEWR----SGK------
---DLRKKCPAIA-------SPV-----TPAKLCCCILII-FILVALNVVTLSTLVAV--
--------------------RSR------------ETDVQ----------VLLAACPEG-
WIGFGSKCFYFSED--S---ENWTFS---QTSCTS-VGAVLAQFEMEE-EL--NFLQRYK
G-----PFDHWIGLSRESS--HHAWKWTDNS---KLD-----AS-----------FVIRG
DGEYAFL---NDF--G------IT-----TSINGAIQ--RRWICSKTNSNVSI----PLH
TSRPF---------------------------

----IWWEAALGEEMAGSQFP-MEPIQNQAQEPEKLGVPEQQVAGEQQLQSSRSPAGPKE
--------PAAAASPSRTRDPPGEK--LSLRPSLLRVPQPSLGYGICQLAA---PGPR--
------------GSGLALVAQPREGETSTPG--PVKETG-EAGSGAWAPVELQVDVRVKP
VGAAVSGLTPSPVPTTR-----FF--------------S--VPVPDSPAFSRHSSLP---
----HWPRTPSPGSTWGRTPLPAGP---IGTGSEGRASPAVRGI------SRGFPCRCR-
-------ELGLEDKEWEKLLPGA-W------DGDKLHQAISLIG-LPAY-----------
---------MKSL-------RWALAVLAVL--------L--AVAVV-----AIVAL----
--------------------------------ASRVGAKC-------------RPCPEG-
WIWSEEHCYYHSLE--V---QSWEDS---KAFCSA-HQASLPVLTHTQ-----DFLSRYQ
T-----HRLYWVGLHRG----SEGWHWINGA---PLS-----PQL-LLDEDED--S--LQ
NRNCGGLE---EG--K------LK-----ALECDS-S--RPWICIKGAK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MPSS--AHLQDAPPLLSRTLTQD--
------------------------------------EEQTSLR------------QSSS-
CG------LS------AASASE--SLSGS------------TKSRIP----HSK------
---MLQGNLPRII-------SPE-----SPAKLPCCYGVI-MVLSV-AVVALSVALSV--
----------------K---KTP------------QILTV----------KTYAACPRN-
WIGVGNKCYYFNET--P---SNWTFS---QTLCKA-QEAELARFDTEE-EL--NFLKRHK
G-----SSGYWIGLHRESS--SQPWKWTDNT---AYN-----NL-----------VPIGG
DEKHGFL---SDN--G------FS-----SGRGY-IV--RKSICSKPNSYTSQ-CQ----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------IGK------
---YLQRKCLTVL-------SPS-----TFPRDFCYLFII-AVLTA-GVVALSIVSS---
-----------------V-RREK------------VVSEP----------TLYAVCPKN-
WIGFESKCFYFSED--T---RNWTFS---QTFCAS-LEGNLARFETLE-EL--NFLKRYK
G-----PSDHWIGLSRESA--QDIWKWTDNT---EYT-----LL-----------FGIRG
VGECAYL---NDN--G------IS-----SARTY-TD--RKWICSKPNSYVSS-CQ----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------DAVWS-------P
LV----------------------------------QSKAIVK-----------------
--------------------------KKL-LPREE---KEET-AFLV----SSK------
---DLRKKCLAIA-------SPV-----TPAKVRCCILII-FILVALNVVTLSTLVAV--
--------------------RNR------------ETDVQ----------VLLATCPEG-
WIGFGSKCFYFSED--S---KNWTFS---QTSCTS-LGAVLAQFETEE-EL--NFLERYK
G-----PSDHWIGLSREPS--HHAWKWTDNS---KLD-----AS-----------FVIEG
IGQYAFL---SAY--G------IS-----SGS-GAVG--RNRICSKTNS-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MMEILYRGS------------QTS-----
----HLSGRHRTTF-D--GKKLLT----LWTVLCGGVII-----LL-W----GF------
---------------FSFPKK-------FGATRTVRNKTCEDE---------MKICMNS-
WNKLNQNCFFIFQH--K---NSWLTA---QETCQH-YEGDLVKFNDKI-EL--ETLMHHV
QA---LGSSAWIGLNKRNI--RKSWVWTDGS---KYN-----NL-----------KTIQE
HGDCAFM---HKN--G------ID-----STSCDD-L--KDYICSKIGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SI--------------TENS-------------ALHV-----------ERGQQS----N
ATSPHFATHREGC----------LQVPVPCAVL---NVVIITVLII-SLIALSVGQ----
YN----CPGQHT-----------------------SSRPSESQ---------LSLCSGG-
WIRHQRKCYFASTT--T---GNWTLA---QNACSK-HGATLTLVDSEE-EM--MFLRQYV
R-----RAEHWIRVKNE-T--GHSQKRLNGK---ELN-----NW-----------SNITE
SENCSFL---GSI--D------VG-----RTECDK-N--LHWICSKPSH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------M-WMAKKQRLLRQLPRQLPAED-TVTFRR---------
--------------------RPAILVGAAV--------I--VIFAV-----LIIAL----
--------------------------------AATAAKTCPKI---------GETCPED-
WLQLRKKCYFSSSE--HESKRNWSDS---QEYCRS-QGGDLVVIENKQ-E-----LVFIQ
Q-----FKNFWIGLHRT----NEGFFWVTGA---PLN-----QSL---------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------RVD-NLSS----G------VRDQP---G------
---------QHG--ETPSLL---------------------------KNTKISQ------
---------------------------------VWSTWSKHAK---------PVACSGD-
WLGVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKAELAQIDTQE-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PKYFL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MAQQ------
--------------DSEATNFSLKCLKEKRIPILVIVVI--TALII-TIIALAAKK----
------------------------------TPPCPS--CSLHV---------TAACPDG-
WVGFQGKCSYFSEM--E---RNWTTS---RNHCAS-LNASLATVDSLA-EL--AFMLRYR
G-----LPFHWIGLQRE-QDQGQPWKWTNGT---IFN-------N-------L--FEVRG
EGQCAYL---NER--G------IS-----SSRCHS-E--RHFICSRPDECSQ-RKPSAAR
GGT-------VSKIT-----------------

MERA---KEAAPESQAGAELP-MEPVGSLLPGLEQPQVPAE----TRQPEGPESSPTPA-
--------GTVEEAVGAGWEPSSEKQLPSPRPGPLRVPPLSLGYGVC-------PEPP--
------------SPGPASAETPRNSEAPGA----------EPAPGAWAPIELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRSTAPAH--
---QLLQCAPYPGGTWGRGSPLAAARKESGRDAEGRASPAEGSAGSPSSPTC---CRCK-
-------ELGLEKEGAALLPC----AGL--DRDKKLPRAVTHLG-MSVY-----------
---------MTSL-------RWALAVMAVL--------L--AVSGI-----VIVVL----
--------------------------------ASRAGTSC-------------QPCPPG-
WVLSEEHCYYLSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DLLSRYL
V-----SKHSWVGARRG----PQGWHWIDGT---PLP-----LEL-LPKDGEN-----NP
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------F--------ADSTC----------PGCPDQ-
WLGYRSSCYFFSKM--K---KDWSSS---QDSCSA-EGSHLLVISDAS-KM--DLFKQMY
------TDTYWIGLRNK-N--GTAWTWEDGS---KLNNTKVLS--------------NSP
VQHCGVL---VKG--V------LQ-----ASSCEV-P--LPWICEKSLK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MAEP-------------------------
------------------------------------------------------------
---------------FPAPRGDGA---RGRRRTAVPGSGCSELRQNRRRVLCVALCAVP-
CILV-SVLVAVIDT--E---SDWNSS---REHCHR-LGASLATVDTEE-EM--SCWGTGA
R------QTVGLGCTGQKG--PEHWTWADGS---AFS-----NW-----------FELRG
GGRCVYL---NGD--G------IS-----SALCHK-E--KFWVCSRADSYVCWRKEKYPE
--------------------------------

--------------------------------MEPPQVPAE----APQPRASEDSPRPER
--------TGWEEPDAQPQELP-EKSPSPALSGSPRVPPLSLGYGAFRRLGSCSRELP--
------------SPSPSWAEQPRDGEAE---LEPWTASG-EPAPASWAPVELQVDVRVKP
VGAAGASRAPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPTL--
---QWLPRAPSPGSTWSRGSPLAANA-------TESVSPAEGCMVPPGSPACRC--RCR-
-------EPGLTKEDDALLQR-----AG--IDGKKLPRAITLIG-LPQY-----------
---------MKSL-------RWALVVMAVL--------L--AVCTV-----AVVAL----
--------------------------------ASRGGTKC-------------QPCPQG-
WMWSQEQCYYLSEE--A---QDWEGS---QAFCSA-HHATLPLLSHTQ-----DFLRKYR
I-----TKGSWVGARRG----PEGWHWTDGV---PLP-----SQL-FPADSED-----HP
DFSCGGLE---EG--R------LV-----ALDCSS-P--RPWVCARETK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------DTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSPK-EL--EFMFKFT
R------R----------------------------------------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------F------
---------IHS--LIKKLKHNI--------VHYLCMVA---WICF-QVC-LSI------
---------------------------------VFAVLSKCPQ---------TMECSGK-
WIGVRKKCFYFSSD--T---KNWTAS---KRFCSS-QGSELAHIDTEE-DM--EFLRRHT
G-----TFMHWIGLNRK-Q--GESWKWTNGT---TCN-----PW-----------FEISG
NGSFAFL---NAD--R------VH-----SSRGFI-D--IKWICSKPKF-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MG----SITPTVLFPCFS--
-------------------------------FFKVLPNCCVKIF-FSAGKRKGRL-----
---DFNARGTRAQ-------RWISQNKVLCVSLCINICF--IISTV-----AYFASP---
-------------------------------QPNNNEQPCISS---------PPLCPDD-
SHMHRKRCYYFSEE--E---YNWTSS---EKFCSS-RNSSLAKIEIDE-Q---DFVERNI
Q-----NYPFWVGLYKS-I--DQQWKWIDGE---NAR-----KPA-G--D----------
GGDCAYLHVFKKM--E------AN-----SGRCST-P--HRFICKSEIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-EC--
-PT--------------TETS-------------SLHQ-----------EKGKKN----N
STSLHFETQHEGS----------LQVPIPCAVL---IVVFNTVLVI-ALIALVVGK----
YN----CPSWYE-----------------------LSLPSNSH---------VSPCPDA-
WVLYRRKCYFFSTT--A---KSWTSA---ESSCSE-DGATLAVIDSEK-DL--IFLKRYA
G-----SAEHWIGLKNG-T--GQIWKWSNGK---EFN-----HW-----------FNLTG
FESCASL---SST--E------VG-----SAECGQ-G--LPWICSRASR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------KIIAVI-LGIF--CLLLLGVSVAL--
AIKRKTCN-LWPEPLYVFCDS--------F--------TDHSC----------LGCPDQ-
WVQYRDSCYYFSKV--K---KDWNSS---QEFCST-QDSELLIISDTR-ER--DLFLGIP
------IEAHWIGMTNV-N--GSGWVWEDGS---TFNDIKVHS--------------NSP
VQHCGVL---LKE--A------LQ-----ASSCEV-P--LPWICEKSP------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------L---VSF-----FFS-VMAFK-
T----------------------------------QQSCPPPR---------PDSCADG-
WIGYKGKCYYFTEA--E---GNWTYS---RSRCSA-LGASLAGIDTKQ-DL--DFMLRYK
G-----TTDPWIGLQRG-T--DREWKWVNGT---KFN-----LL-----------FEVRG
DADCAYL---KET--A------VS-----ASRCYI-M--RSWICNKPYASSTEGRFTQTH
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------G-LPMY-----------
---------MKSL-------RWALAVMAIL--------L--AVSTV-----TVVVL----
--------------------------------ASRVGGGC-------------QPCPQG-
WMWSEEYCYYLSVE--A---QTWEAS---QAFCSA-HHATLALLSHTQ-----DFLIQNQ
V-----AKYTWVGARRG----PQGWQWIDGA---LLP-----SQL-LSEEEDD-----NP
DLNCG-LE---KD--R------LL-----ALDCTA-L--RPWLCAKGAK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MLEVFS----
------------------------------------------------------------
-------------------------------------SR-------A--DCVTH------
----ELLSVWLGS-RCSELRQNRRR--VLCVALCAVPCI--LVSAL-VAVI---VL----
--------------------------------QRPSCSPRPPF---------SHVCPNT-
SIGFQGKCYYFSDT--E---SDWNSS---REHCHR-LGASLATIETDE-EM--EFMLRYR
G-----PANCWIGLHRA-E-GDEHWTWADGS---AFT-----N---------W--FELRG
GGQCAYL---NGD--R------IS-----SALCHN-E--KFWVCSTADSYVRWKQKAFPD
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------RSA-------------SDIY
FTL----------------------------------NFPTAFQAQDNYRPQQN------
------------------------------------------GLL--NVLLIS--LLL--
YQ-------------WILCKG--------PGD-S----ACASC----------SSCPDF-
WMRYKNHCYYFSVE--K---KDWNSS---LEFCTA-SDAQLLILTDNQ-EM--SLLQNLI
N-----QDFHWIGLRKN-----SSWRWENGS---PLNFSRISS--------------NSL
VQRCGAI---SKE--G------LH-----GSSCEV-L--LQWICKKARL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------KALAQRCAVL----NLLLVVL-L---ASLV-VILIII--LA---
-------------------------------------ARPAIS---------NGACPDG-
WVGYRGKCYYFSES--E---ATWTDS---QKNCSA-HGASLAGIDSPQ-EM--DFIRRYK
D----PSSRYWIGLRRE-P--GQPWKWTNGT---EFN-----SL-----------FRVRG
ERQCAYL---DDR--E------VS-----SARCYV-E--MHFICSRPDECSRRKLSAA--
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------EPACPSE-
WVGYCNVCYYLSGQQEQ---GNWIWS---QEQCSR-HGASLVVVNKDR-EL--KFLRQFK
D-----NGDSWLGLRRR----GEHLLWVDGS---SFN-----L---------T--FPVQG
SAECICL---NGV--D------MA-----TSSCWQ-S--PPYICSKPLAV----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGE-----------G-DQQ-
-E-------------------------------TFSEHK-------AALQPLGQ------
-----------SS-WCHGTGRRRSR--VQLIAACAALGT--LSLVL-V--VISTAC----
--------------------------------RQVPVPPFPDF---------AHACPNA-
WVGFQGKCYYFSKE--E---NDWNSS---REHCNA-HGASLASIDSED-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKAHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----LQRKCLTVL-------PPL-----TLAKFSYCLFII-AVLTA-GVVALPIVLS---
-----------------V-RQKK------------VVSAP----------SLYAACPES-
WIGFGSKCFYFSKN--A---RNWTFS---QTFCAS-LEANLAQFETLE-EL--NFLERYK
G-----PSDHWIGLSRESA--QDIWKWTDNA---EYT-----LS-----------FDIRG
FGECAYL---NDN--G------IS-----SARIY-TD--KKWICSKPNSYVSS-CQ----
--------------------------------

MERA---REAPAGGPAGAELP-AEPAESRVPELQQPQVPAE----AQQLESPDGSPS-LA
--------RTARDAAGAGPDAPGEKKPSPPRPGLLRVPPLSLGYG-----------PP--
------------SPGPASAEQLRNGEAPG------------PAPGAWAPVELQVDVRVKP
VGAAGGSRAPSPAPSTR-----FL--------------T--VPVPESPGFSRHASPAH--
---PLLQRAPSLSGTWGRGSPLAAAGTDSGRDAEGRASPAEG---SAGSPTC--RCRCK-
-------ELGLEREDA-VLLH---------PGDKKLPRAIGLIG-LPMY-----------
---------LKSL-------RWALAVMAVL--------L--AVSAV-----AIVAL----
--------------------------------ASRAGVRC-------------QPCPQG-
WMWSEEHCYYLSAE--A---KAWEAS---RAFCAA-HGATLPLLSHTQ-----DFLSRHP
V-----TKYSWVGAQRG----PQGWHWIDGS---PLP-----PQL-LAEDDED-----NP
DLSCGGLE---EG--K------LV-----AMDCSS-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------K------
---SLQGKLLAVI-------YPV-----TPIKIYLCFFII-SVLIA-SVIALSIILS---
-----------------A-KKTE------------PIVQN----------LVFATCPED-
WIGFGNKCFYFSED--V---GNWTFS---QTFCAS-LASNLAQFESQE-EL--NFLKRYK
G-----LSDHWIGLNRESS--HHIWRWTDNT---EYK-----AL-----------FSIRG
DGECAYL---NDN--G------IS-----SARHY-TD--RKWICSKPNSYFHK-CQITSS
S-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDPAR--ETLRT--GIYPSIPG---------HPEGA-------
---------------RPGNSHGCQLWKQVACTVALAVVL--VGLIV-AIAVLSVLV----
------------------------------------SKTPPRL---------MPWCPDG-
WLGYQGKCYYFSEA--E---LSWNDS---RMNCSA-FGASLAGIDSKQ-QLLQMFMMRYN
G-----DLEHWIGLWRG----NQQWTWVNGS---NFN-----S-P-------S--LLIRG
GGDCAYL---SAK--S------IS-----SSRCTT-E--RNWVCSQPDAHTVQQSVMLRS
QELQHP--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTS-----------E-DC--
-SI--------------METS-------------SLHL-----------NKERQS----D
APRPHFATHHEGS----------IQVPIPCAVL---NVVFITVLII-ALVALSVGQ----
YN----CPGQYM-----------------------SPVPSNSH---------ASSCSDD-
WIQYQRRYYLISKK--T---RNWTLA---QEFCSK-HGATLALIDSEE-DM--IFLKQHV
G-----RAEHWIGLKNE-A--GQTWKWSNGK---EFN-----NW-----------FNLTG
SENCAFL---NST--E------VG-----SAACEK-N--LHWICSKPAK-----------
--------------------------------

MERA---GELSPGGLPGAEFP-AEPVESQVPDLEQPQIPAE----TQQPESPQGSPT-LA
--------RTAKDAAGAGLDPPGEKKLSPPRPGLQRGPPLSLGYGAFRRLGSAGPEPP--
------------SPGPASAEQPRDGEAPGSELLPWAAPG-EPAPGPWAPMELQVDVRVKP
VGAAGGSRAPSPAPSTR-----FL--------------T--VPVPESPAFPRHASPAH--
---PLLQRTPSPGSTWGRGSPLTTARIESGRDAEGRASPAER---SAGYPTCRCRCRCK-
-------ELGLENEDS-VLLH---------PGNKKLPRAIALLG-LPTY-----------
---------MKSL-------RWALAVMAVL--------L--AVSAV-----TIVAL----
--------------------------------ASRAGVRC-------------QPCPPG-
WVWSEEHCYYLSVE--V---QPWEAS---QAFCSA-HSATLPLLNHTQ-----DFLSRYP
V-----TKYSWVGAQRG----PQGWHWIDGS---PLP-----PQL-LPDDDKD-----TP
GLSCACLE---EG--K------LV-----AMDCSS-P--RPWVCAKGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MMVP----E------LCDSSHDSW------
---------IRG--AICKLIC--------------CVCA---LS----ITVVIL------
---------------------------------LTAKFSKYPQ---------AMECPEK-
WIGARDKCFYFSDD--T---RNWTAS---RRFCSS-QRSELAQIDTPE-DM--KFLKMCT
G-----TSMHWIGLSRA-L--GESWRWTDGA---TFN-----A-----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------IK--DTCKKYSACAFI--LA----ILLVA--N---I-VLIVLVIK-----
--------------------------------------IAQGA---------RHYCPDN-
WIGSKDKCYYFSKE--E---KDWNSS---RYNCTS-QHADLAEIDTAE-KM--EFLMRFK
C-----SWDHWIGQVKT-E--IQTGQSIDGT---VF------K---------N--WDLRR
NEICTYN---ENG-----------------TARYT-E--RKWICQKKIG-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------FPPRSLREVLAKKSA
PPAPLCPQP---------------------------------------------V-PHL-
-HG--------------AKGER--ERR------SPSPPR-------EATAREGD------
----EERQSQRGS-GCSELRQNRHH--VLCVA---VLCI--LVLAL-VAVI---VL----
--------------------------------QRLSCLPPPPF---------SHVCPNA-
SIGFQGKCYYFSYT--K---SDWNSS---REHCHR-LGASLATVDTEE-EM--EFMRGYR
R-----PADRWIGLHRA-E-GDEHWTWGRW----------------------Q--FELRG
GGQCAYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVL--------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------V------
---------------ISRHK--------K------CFIM---GAIL-II--------I--
-------------------SN---------AITVLIGKL---------------------
-----HSIFYFSGY--S---MYWNSS---RYNCST-QHADLTKIDSKE-EM--DFLRWHK
C-----SSDHWIGF------------------------------------------VMKG
SEECTYL---SDD--G------TA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MT-
---------QSPLILTQ----------TD-HRNQ----G------TDE-KKQGL------
---------------KNSYK--------K------ILIC---ILLA-ISFTVI--N----
------------------------------IVITGIGLVCKNT---------QDSCPDD-
WIGFQKKCYYFSKE--E---QDWNSS---RHNCVT-QHADLTMIDTDE-EM--GFLKRYK
C-----TSDHWIGLEMT-E--NQTGRWVKGT---IFN-----KR-----------FPVRG
SEKCAYL---DDN--G------AA-----TARCYT-E--RKWICRRKMH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFII---VGVL-I------------
-------------------TT---------NIITLIVKLTRDS---------QSLCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNIE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---TFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKRIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREP-------------
---PARARPPPPA-----ARPA-----------------------PAAPRPRS---PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
MGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

MERA---KAAAPESQAGAKVP-MEPVGNLLPRLEQPQVPAE----TRQPEGPESSPTPA-
--------GAGEEAAGAGREPSSEKQLPSPRPGPLRVPPLSLGYG-----------PR--
------------SPGPLSAETPRNSEAPGA----------EPASGAWAPIELQVDVLVKP
VGAAGGSSPA--------------------------------------------------
-------------------------------------SPAEGSADSPSSRTC---CRCK-
-------ELGLEKEGAALLPC----AEL--HRDKKLPRAVTHLG-LSMY-----------
---------MKSL-------RRALAVMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYLSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DLLSRYP
V-----SKHSWVGARRG----PQGWHWIDGA---PMP-----PQL-LPEDGEN-----NS
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

--------------------------------MEPPQVPAE----APQPRASEDSPRPER
--------TGWEEPDAQPQELP-EKS--PALSGSPRVPPLSLGYGAFRRLGSCSRELP--
------------SPSPSWAEQPRDGEAE---LEPWTASG-EPAPASWAPVELQVDVRVKP
VGAAGASRAPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPTL--
---QWLPRAPSPGSTWSRGSPLAANA-------TESVSPVEGCMVPPGSPACRC--RCR-
-------EPGLTKEDDALLQR-----AG--IDGKKLPRAITLIG-LPQY-----------
---------MKSL-------RWALVVMAVL--------L--AVCTV-----AVVAL----
--------------------------------ASRGGSKC-------------QPCPQG-
WMWSQEQCYYLSEE--A---QDWEGS---QAFCSA-HHATLPLLSHTQ-----DFLRKYR
I-----TKGSWVGARRG----PEGWHWTDGV---PLP-----SQL-SPADSED-----HP
DFSCGGLE---EG--R------LV-----ALDCSS-P--RPWVCARETK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------PPL--
PRCS---------------CL---------ISASLPGRSPRVP---------GPACPDD-
WVGYRGKCYHFSEA--E---RNWTDS---RSNCSA-LGASLAAIETLK-EM--AFMLRYS
G-----SSDYWIGLCRA-R--GQPWKWTNGT---EFN-----SLC-------LQPFPIAG
DDDCTYL---DGN--R------IN-----SLQCTS-E--RRWICNKPDVLTEA-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-DC--
-SI--------------TENS-------------SSRL-----------ERGQKD----H
GTSIHFEEHHEGS----------IQVSIPWAVL---IVVLITSLII-ALVALNVGK----
YN----CPGLYE-----------------------KLESSDHH---------VATCKNE-
WISYKSKCYFFSTT--T---KSWALA---QHSCSE-DAATLAVIDSEK-DM--TFLKRYS
G-----ELEHWIGLKNE-A--NQTWKWANGK---EFN-----SW-----------FNLTG
SGRCVSV---NHK--N------VT-----TVDCEA-N--FHWVCSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MLTDTSPRLP------------QTS-----
----HELRHRRLMF-D--SKKVLT----LWTLLGGAVAV-----LL-W----GF------
---------------FSFPRK-------FTVTRTARNKTCEDG---------VKLCPKD-
WNKLRRNCFSSIQH--K---SSWLTA---NDTCEL-HDATLAVFIDKT-EL--EILMNQM
Q----EMKTYWIGLHRQNL--LGIWVWTNGS---KYN-----NL-----------HDIQD
HGQCAFV---HQK--G------ID-----STNCED-Q--KEFICTREGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LGS------GD---VGEACTDSLPPDSTVYLCG-LSY-
------------------KLSR-----G----CSVTCKA---------IAEPSCG-L--A
A-----AT----------------------TIII-TII----IIIMAIQTVLGTRT----
--------------------------------FKDPSKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCRT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DTHR--FPISG
LGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKTAYTVQSPLLVTPS
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPAR----------
------ARPPPPP-----TAPAAP---------------------AAPAAPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------XEGRASPADGRSEPPGSPTC--LGRCR-
-------ELELEKKEDAALLHR---AET--GGDEKLPRAVKFIG-LPMY-----------
---------MKSL-------RWALAVMAVF--------L--AVSAV-----AIVAL----
--------------------------------ASRAGTRC-------------RPCPQG-
WMWSEERCYYLSAE--A---QAWEAS---QAFCSA-HQATLPLLSHTQ-----DFLSRYP
V-----TKYSWVGARRG----PQGWHWIDGA---PLS-----PQL-LPEEEED-----QP
DLKCGGLE---GG--K------LV-----ALDCAS-P--RPWVCAKGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MA------EPSPPR-------EAMACEGE------
----EERQSQRGS-GCSELRQNRCC--VLCVALCAVLCI--LVLAL-VAVI---GE----
--------------------------------S---PIPPPGL---------PTWCPKAP
SAPTPGKCYYFSYT--K---SDWNSS---REHCHR-LGASLATVDTEE-EM--GFIMQYH
G-----PEDHWIGLHRA-E-GAEHWTWADGS---AFS-----N---------W--FKPQG
GGQCVYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVLWRNGTNPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------CLT-FVQFLISVC----
--------------------------------RQVPVPPFPDF---------AHVCPNA-
WVGFQGKCYYFSEE--E---NDWNSS---REHCNA-HGASLATIGSAE-EM--DFMMRFQ
G-----PAICWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--SVCLS
SCPGH----------D------FP-----RALFGM-G-TFSWCHSLPFAHLGWR------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------DQIENRG---------TCSDICSRD-
WIGFGSKCFYFSED--M---RNWTSS---QTSCMA-LDAQLARFDNLE-EL--NFLKIYS
E-----TFNHWIGLHRESS--KHPWRWTDDT---KYN-----SL-----------NFIRG
EGKYCYL---SDR--G------IS-----SSRNY-MP--RKYICSKPN------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MA------EPSPPR-------EAMACEGE------
----EERQSQRGS-GCSELRQNRCC--VLCVALCAVLCI--LVLAL-VAVI---VL----
--------------------------------QRPSCPPPPPF---------SHVCPNA-
SIGFQGKCYYFSYT--K---SDWNSS---REHCHR-LGASLATVDTEE-EM--GFIMQYH
G-----PEDHWIGLHRA-E-GAEHWTWADGS---AFS-----N---------WSVFKPQG
GGQCVYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVLWRNGTNPQ
--------------------------------

MELA---GEAPAGGLAGAEFP-TEPTESRVPELEQPQVPAE----AQQPESPDSSPS-LA
--------RTARDAAGAGPDLPGEKKPSPPRPGLLRVPPLSLGYG-----------PP--
------------SPGPASAEQLREGEAPG------------PAPGAWAPMELQVDVRVKP
VGAAGGSRAPSPAPSTR-----FL--------------T--VPVPESPAFSRHASPAH--
---PLLQRTPSLGGTWGRSSQLAAAGTDSGRDAEGRASPAEG---SAGSPTC--RCRCK-
-------ELGLEKEDA-VLLH---------PGDKKLPRAVGLIG-LPTY-----------
---------LKSL-------RWALAVMAVL--------L--AVSAV-----AIVAL----
--------------------------------ASRAGVRC-------------QPCPQG-
WMWSEEHCYYLSAE--A---QAWEAS---RAFCSA-HSATLPLLSHTQ-----DFLSRYP
V-----TKYCWVGAQRG----PQGWHWIDGS---PLP-----PQL-LPEDDED-----NP
DLSCAGLE---EG--K------LV-----AMDCSS-L--RPWVCAKGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------LKSRAL--PLAV--LSLVL-NLILISVII----
--------VMLCSL----------------------STPAADP---------VAACPDG-
WVGYLGKCYYFSEA--E---ANWTDS---QKNCSA-LGASLPGIDTQQ-EM--DFLARNQ
G-----SFDHWIGLHRE-P--DQAWKWANDT---EFN-------N-------W--FPIVG
EAQCAFL---SRN--S------VA-----SSGCSN-ANRTHWILADLCELELWGRLFSPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FI--------------TENS-------------SLHP-----------ESGQEN----D
ANSPRFSTQREGF----------FQVPVLCAVV---NVVFITILII-TLIALSVGK----
YN----CPGQYT-----------------------FSVPSDSN---------ASSCPDD-
WVGYQRKCYFISTA--K---KSWTSA---QNACSE-RGATLAVIDSEK-DM--NFLKRYA
G-----RGEHWVGLKKE-P--GQTWKWSNGK---EFN-----NW-----------FNFTG
SEKCVFL---KNT--E------VS-----SMECEK-N--LHWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------LLTVV-L---FILI-IIIVLA--VTF--
N---------------------------------PS-SADPAA---------AHCCPDG-
WVGYQRQCYYFSEA--E---ESWTDS---QDHCFS-LGASLAGIDTQQ-DL--AFINRYK
G-----LSEHWIGLRRE-P--GQPWKWTNGT---EFN-----HW-----------FEVRA
DGECAYL---NDV--A------VT-----SSWCDT-V--RYWICSKP-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MSAA---------------------
----------------------------------------NVE------------ESSM-
GML---Q------------RTD--LT------------AADCLQEGE----MGK------
---KIQGKCLRII-------STE-----SRAKLYCCYGVI-MVLTIA-VTALSVALS---
-----------------MRNKNP------------VMENRE---------PCYTACPSG-
WIGFGSKCFYFSED--M---GNWTFS---LSSCIA-SSSHLALFDSLE-EL--NFLKRYK
G-----ASDHWIGLHRAST--QHPWIWTDHT---EYN-----NL-----------VLTRG
GGECGFL---SDN--G------IS-----SGRSY-TH--RKWICSKFASSCKSRVGSVPK
PV------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------M-TVKEPTPRASEMESERIENR---KV-----
----VEQRIKRPGI-V--TKKMLI----MSSMICGGIAF-----LL-W----AV------
---------------LGFPQK-------SKNPVIFNNKTCSED---------AIICPQS-
WNQINNNCFFQSER--E---KTWMDG---QTKCTA-HSGSLAIFNSKN-EV--ESLMPYL
G----P-SCYWIGLKMDSK--SKLWIWTNGD---VFS-----NW-----------FSIDG
SGECACM---FQK--G------IS-----SGNCSD-A--RKYTCSRKGFCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MMLENVYRAS------------QTS-----
----HAPGHHRATF-D--GKKLLT----LWTLLCGGVVV-----LV-W----AF------
---------------FTLPRK-------FGNARVIRNKTCDDE---------VKICSST-
WLKINQNCFFLFQH--K---NAWLSA---QENCQH-YEANLAKFTTKM-EL--ETLMRHV
QS---LRSSFWIGLNRRNL--RRFWVWTDES---IYN-----NV-----------KEVQD
HGDCAFM---HKS--G------ID-----STNCDE-L--RDYICSKLGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-HC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSDD-
WVSYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNFTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ME--EMRIY-SGVLGMERN----------KRAGN------
----S-----RGT-CTCQVM----------LA----VLF--TSLFI-TAIAFAVQ-----
-----------------------------------AFQPHPQP---------CFQCPFD-
WIRYRGKCYYFSEV--E---GNWTSS---QDNCSA-LGASLAMLDSAE-DL--SFVMRYK
G-----ISEHWIGLLRA--DEEQPWQWVNRS---PL------SH--------L--FQIHG
SGLCAYL---DDN--G------LS-----SSHCST-E--RSWICNKHELQ----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MT----------------------------------STEVFLK-----------------
--------------------------ILE-TDPTY---RENT-EAWR----SGK------
---GLQKKCLAIT-------SSV-----TPATLCCCILII-LILVALNVVTLSVLLAV--
--------------------RSR------------ETDLQ----------VVYVTCPKG-
WIGFGNKCFYFSED--S---ENWTLS---QISCTS-VGAVLAQFETEE-EL--NFLTRYK
D-----IFDYWIGLSRESS--HHAWKWTDNS---KLN-----VP-----------FVIQG
TGECAYL---TDS--G------VS-----SGKRY-VI--RKRICSKTNSNVSI----SLE
SAVQHM--------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-PC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSDD-
WISYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNFTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYKS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FV--------------AENS-------------SLHP-----------ESGQEN----D
ATSPHFSTRHEGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSED-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSEK-DM--NFLKRYA
G-----REEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNVTG
SEKCVFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------LPLY-----------
---------MKSL-------RWALVVMAVF--------L--AFCTV-----AIVAL----
--------------------------------ASRGGTRC-------------QPCPRD-
WLWSQEHCYYLSEE--A---QDWEVS---QAFCSA-HHATLPLLGHTQ-----DFLRKYQ
I-----TKDSWVGAQRG----PEGWHWIDGV---PLP-----SQL-SPEDSDD-----HP
DFSCGGLE---EG--R------LV-----ALNCSS-P--RPWVCARETK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------RKPE------------EVSIK----------CVCAFCPRD-
WIAFGSKCFNFSEK--V---ENWTSS---QTFCVA-QGAQLARFDSQE-EL--EFLKRYK
G-----EHDHWIGLHRKSS--EHHWMWTDGT---EYN-----NL-----------TSPRG
GGECAYL---SDS--K------VS-----SGRNY-TH--RRWICSKPNSFTA--CDVPKQ
S-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------TIAIYIVKLIQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKVA-K--NRTGQWVNGA---VFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------IQN----NFPCFSDGTVE-----LK-WYTILIP------
-------------------ST--AGIILIVVLIALASKTCPKC---------DETCPDG-
WLQLRNKCYSYNNG--N---INWPKS---KEVCKS-QGANLVVIESHQ-EL--DFSFFPL
QSFVQKFKGHWIGLFRV-------RTWVKGQ---QYEVEEIKVQ-----------FPVTD
PGNCAYI---STN--K------IA-----TNGCNE-S--KPFVCSMSLTVT---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFII---VGVL-I------------
-------------------TT---------NIITLIVKLTRDS---------QSLCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNIE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---TFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKRIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------IRQ--TICNFKPNW--------KICLCVCF---VIII-IYAACII------
---------------------------------MIVKWPKCDK---------RVACSGD-
WLAVREKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYSL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FV--------------AENS-------------SLHP-----------ESGQEN----D
ATSPHFSTRHEGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSED-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSEK-DM--NFLKRYA
G-----REEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNVTG
SDKCVFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MQSDHK-DASKEEA--DE--------------------------KK------
----------RD--VNDKQYKHCKRR--LIFALAISVVI--NVLTN-IVIYFSVK-----
--------------------------------------EDRIA---------QYFCPDN-
WIGFQDKCYYFSEE--E---EDWNSS---RYNCLS-QNASLVMIATTK-EK--RFLMRFK
C-----TSDHWIWQDMT-E--NLTGQWVDEN---IHN-----K---------G--INMTE
NEICFYL---NED--G------VA-----TARCYT-E--RKWICRKKVH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTS-----------SCTSI-
---------HLLEEPPSVEAIRFHQCLCL-QGEQ----Q------ALPASTGGA------
---------PRQ--AVCKLRKDW--------WKKFLICV---LVVV-TGLYFSV------
---------------------------------SRLISSESTK---------AMECSEE-
WIGVRRKCFYFSDD--T---RNWTAS---KRFCSS-HGSELAQIDTPE-DM--KFLKKHA
G-----TSMYWIGLSRK-L--GESWKWTNGT---TFN-----AG-----------FEISG
NGHFAFL---NSD--G------VH-----SSRGFV-D--IKWICSKPISKTENKLGNQQR
ILQ-----FFLIEV------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MQSVQIPILKHKVST----------PAEGERLNHLSEH--KAAPEPPAHQRRRIPTSSD
PQ---LPEED-VH-----ISVLESNT----------STPTMGE-----------G-DQQ-
-E-------------------------------TFSEHK-------AATEPLGQ------
----SGEKPQWGS-WCHGMGRRRSC--VQLIAVHAALGA--FILML-VVLVISTAC----
--------------------------------RQVPVPPFPDF---------AHVCPNA-
WVGFQGKCYYFSEE--E---NDWNSS---REHCNA-HGASLATIGSED-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKVHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MAD-------------SDIY
CTL----------------------------------ELPATPQVQEDSRSKLRA----L
--------FRRL------------------P-LSCLVTVA-LGLL--TV--ILVGLLM--
CQ-------------RIPCCG--------SKD-S----VCAHC----------PSCPNL-
WMRNGSHCYYFSTE--K---KDWNSS---LEFCAD-KGSHLLMFLDDE-EV--IPFQKYL
D-----NDFYWIGLRKT-----DGWRWEGGP---ILS-LRIVS--------------NSL
IQTCGTI---HKD--G------LQ-----ASSCEV-P--LRWICQKTTN-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------MIKENMCTGN---------VSHCLQG-
WNQVSNNCFLQSDH--E---TTWMNS---QENCKV-YSASLARISSQE-EM--ESMILFL
K----P-FSYWIDLSKHNG--NSSWEWEDRS---PIN-----NW-----------FSVQG
NGDCLYI---DKT--G------IS-----ASDCND-L--RRYICSRKSHCL---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------S-----
-------------------------NCVE-KACVPVEL----------LRNPNY------
---------------LPSKK-HSTKVKRNRAFSFIITC----FIL----ILNGIIIYVV-
---------------VT--------------RRKPHQIPPECL---------EAACPEN-
WIGFQRKCFYFSDD--I---KNWTFS---QRFCVS-HGADLVQIETVQ-EL--GFLLRYK
G-----PSDHWIGLSRE-E--GQPWKWINGT---EWT-----SC-----------FPIRG
GGECAYL---NDN--G------AS-----SARHYT-E--RKWICAKEDRS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREP-------------
---PARARPPPPA-----ARPA-----------------------PAAPRPRS---PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
MGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------LIL-------
----------------------------------HFAPAASPA---------GPWCQDG-
WIGYQGRCYYFSEA--E---ATWDTG---QSNCSS-FGANLAVINTAQ-EK--AFLLRYK
G-----LSEHWIGLWRE-E--GQPWRWVDGT---EFN-----TL-----------FEVRA
DGHCAYL---NDD--A------VG-----SSWCHT-R--RNWICTYPDAYAKG-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEEEE--------------
----LENRRKRRAE-V--KRKMII----LSVLLCGGFAI-----LL-W----LM------
---------------LKFPRK-------IGIKI--MNKNCTDD---------MRMCPPD-
WDLIIQKCFFQSEH--E---MTWVEG---QRHCRK-YFASLAKITSWT-EM--ESLADYL
N----S-STYWIGLRKHNS--DNIWRWMDGS---HFN-----NW-----------FTIVD
SGNCASV---DAS--G------VS-----ITSCDG-T--RRYLCSKKSHCA---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SKN---
---------------------------VE-KDIA----P------SELPANPGY------
---------------RHSKEHSS-----KATLIWPLFFL---IMFL-TIIACGVVV-F--
-------------------SA---------IRANCHQKSSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDANLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------LVIKE
DGANLYV---AKVSQV-------PMNPTLVMVSYP-G--SRRVCLFE-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLLS--VLL--
YQ-------------WILCQG--------SNY-S----TCASC----------PSCPDR-
WMKYGNHCYYFSVE--E---KDWNSS---LEFCLA-RDSHLLVITDNQ-EM--SLLQVFL
S-----EAFRWIGLRKN-----SGWRWEDGS---PLNFSRISS--------------NSF
VQTCGAI---NKN--G------LQ-----ASSCEV-P--LHWVCKKCPF-ADQALF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------TRS-------------NAIY
CTL----------------------------------ELPSTVQVQDDCSPQRRA----S
--------SSRP------------------S-LFCLVVIV-LGLL--NVLLAS--LLL--
SQ-------------WILGQG--------PNR-A----TCASC----------PSCPDF-
WMRHANHCYYFSVE--Q---KDWNSS---LEFCTA-RDAHLLMILDNQ-EM--SLLQNLI
D-----QDFRWIGLRKN-----SSWTWEDGS---VLNFSRVYS--------------NSL
VQRCGAL---NRA--G------LQ-----GSSCEV-P--LRWVCKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------AILATS-VIALSVALSE--
----------------KEKKERF---------------SIK---------NICAVCPKD-
WIGFKSKCFYFSED--M---RNWTLS---QTFCMA-QEAHLAQFESKE-EL--NFLMRYK
G-----DSAHWIGLHREST--QHPWRWTDNT---EYN-----NL-----------VPIRG
EGERAYL---SDR--G------IS-----SGKDH-TT--RKWICSKFHSLC-Q-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-NS--
-FI--------------TEDS-------------SLHL-----------ERGQED----T
TTSPHFAKHHEGS----------LQVPIPCAVL---NVVFITILII-TLIALSVGQ----
YN----CPGQSM-----------------------FPMPSDSP---------VSSCSDD-
WVGYQRKCYLIFTS--T---GNWNSA---QNACYE-LGATLAVIDSEK-DM--NFLKQYV
G-----QTEHWIGLKKE-A--GQTWKWSNGK---EFN-----NW-----------FNLTG
SENCAFL---NST--E------IN-----NKECEN-K--LHWICSKPSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MIS---------------EDE--EIAQQ-KNEVFFHHK----------ARDKT------
----DKQRLFRITLIISATL----------LS----VVY--IVAFV-ITADYLLHAEN--
H----------------------------------NKLGHGCV---------CPSCPDD-
WIGYRRKCYYFSLE--K---RNWTSS---QDFCSS-QKAFLLIFNDNK-EK--EFVMQYK
G-----KVPSWIGFRKN-P--DQIWRWTNNE---NA------IK--------L--GVIGK
GGDCAYL---NSEG-T------AT-----ASRCGI-E--LRWICSKHDLCNRST------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MT----------------------------------TTEVSLK-----------------
--------------------------ILE-TDPTY---RANM-EERR----SGK------
---DLRKKCPAIG-------SPV-----TPAKLCCCILII-FILVALNVVTLSTLVAV--
--------------------RSR------------ATDLQ----------VLLAACPEG-
WIGFGSKCFYFSED--S---ENWTFS---QTSCTS-VGAVLAQFETEE-EL--NFLQRYK
G-----PFDHWIGLIGEPS--HHAWKWTDNS---KLD-----AS----------------
------------------------------------------------------------
--------------------------------

MERT---QEASGGGQAEAWSP-EEPLKRPDTEYVEAPPPPP----PPPPEAPDGHPRAER
--------TGREAADAEPREPREEKPQPPAPCGTPRLPPLGLGYGAFRHLGSSSREPP--
------------SPSPS-----RDGEAE---QPPWAASG-EPAPGAWAPVELQVDVRVKP
VGAAGASRSPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPAP--
---PRLPRAPSPGSTWGRGSPLAATPTTTP---SELIGAAEGSAVPPDSPTCRC--RCQ-
-------GSGLTKEDARLLQS-----AG--MDSKKLPRAVTLIG-LPLY-----------
---------MKSL-------RWALVIMAVF--------L--AVCTV-----AIVAL----
--------------------------------ASRGGARC-------------QPCPRG-
WLWSQEHCYYLSEE--A---QDWESS---QAFCSA-HHATLPLLNHTQ-----DFLRKYQ
I-----TKDSWVGAQRG----PEGWHWTDGV---PLP-----PQL-FPEDSED-----HP
DFSCGSLE---EG--R------LV-----ARDCSS-P--KPWVCARRVK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------S--EA---------KADLPASAAVTGN---------APCCPPG-
WIMNVGNCYHALEL--E---GTWEAG---QQHCSS-LGASLAVFDNLE-KL--DDAMNDK
S-----PYNHWIGLLRE-P--EESWKWMDGT---LFN-----N---------L--FEIKG
DGRCAYL---THG--S------VS-----SADCSV-K--KKCLCSQSVKINHGH------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------SQPTFLS----FA-K
GLG-A-KA----Q--------------------------------PHPS--------AL-
------------------APGS-----P----EEGR--------------SSSFR-L--M
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTISG
LGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MPSS--AHLQDPPPLLSRTLTQN--
------------------------------------EGQTSLR------------QSSS-
CGP---CGPS------AASASE--SLSGS------------TESRIP----HSK------
---MLQGKLPRNI-------PLE-----YPAGLYCCYVVI-IVLSV-AVVALSVALSV--
----------------K---KTA------------QISTI----------NTYAACPRN-
WIGVGNKCFYFNEI--P---SNWTLS---QTLCKE-QGAELARFDTEE-EL--NFLRRYK
G-----SSGYWFGLHRESS--AHPWKWTDNT---EYN-----NS-----------VSIGG
DEKHGFL---SDN--G------FS-----SGRGY-IV--RKSICRKPNSYTSQ-CL----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------SPTCRC--RCQ-
-------GSGLTKEDARLLQS-----AG--MDSKKLPRAVTLIG-LPLY-----------
---------MKSL-------RWALVIMAVF--------L--AVCTV-----AIVAL----
--------------------------------ASRGGARC-------------QPCPRG-
WLWSQEHCYYLSEE--A---QDWESS---QAFCSA-HHATLPLLNHTQ-----DFLRKYQ
I-----TKDSWVGAQRG----PEGWHWTDGV---PLP-----PQL-FPEDSED-----HP
DFSCGSLE---EG--R------LV-----ARDCSS-P--KPWVCARRVK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-DC--
-SI--------------TENS-------------SLHL-----------ESDQKD----V
AASYRFAASHEGS----------LQVPVPCAVM---YVVFTTILVI-ALIALSVGR----
YN----CPSQCE-----------------------FSAPAESH---------VSSCSDD-
WIGYQRKCYYISTT--T---YNWTLA---QNFCSK-LGATLAVIDPAK-DM--SFLQRYA
G-----GAGHWIGLRNE-A--GQTWKWSNGK---DLS-----NR-----------FNITE
SESCAYL---NST--G------IG-----STGCDK-S--LHWICSKPSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MGA
DQ----------------------------------PAEAFVG-----------------
-------------------------------MLGT---THRLQE-GE----MGK------
---KLQGQCFRIV-------SVE-----SPVKLYCCYGVI-TVLTV-AVFALSVALS---
-----------------V-RRSE------------QTPDK----------YTYAFCPRN-
WIGFGSKCFYFSEN--T---NDWTFS---QNFCKE-QEAHLAQFDSDE-EL--EFLKRYK
G-----AFDYWIGLRRESP--EHPWMWTDNT---QYN-----SS-----------VSIRG
VEEYAYL---NNN--G------IS-----SARVY-AD--RRWICSKPSSYALQ-CQIPFS
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MI----S------NYIVVMIGF------
---------------MSRHK--------K------CFII---GAIL-I---------I--
-------------------SN---------VITVLIVKPTPDS---------QRFCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHAVLTKIDSNE-EM--DFLRRHK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---KFE-----NS-----------FVVKG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRQKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------ME-----PAREPPAR----------
------ARPPPPP-----PASRPA---------------------PAPAAPRPRS-PAE-
------------------AEGR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCRT-HDAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FSISG
PGECVFV---EPT--R------LA-----STECLM-T--RPWVCSKTAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-DR--
-SV--------------TENS-------------SLNL-----------EQGGRD----N
STSPRFTTHREGS----------LQVPIPCAVV---TVVIITILII-TLIALQVGQ----
YN----CP-----------------------------VPSNSH---------ASSCSDD-
WIGYQRKCYFISTE--K---KNWTSA---QNECSK-HGATLAYVDSEK-DM--MFLMRYV
S-----RTKHWIGLKKE-G--NQTWRWANGR---EFH-----NW-----------FSLSG
SENCVFL---NGT--E------VS-----STECEK-R--LHWICNKPSRE----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-GC--
-SL--------------TENS-------------SLHL-----------ERGQQN----D
ATHSHFTTHHEGS----------LQVPIPCAVM---GVVFTTILII-ALIALSVGK----
YN----CPGQFS-----------------------VPAPEG-A---------ASSCSDD-
WVGYQRKCYYFSAE--T---HSWPLA---LKSCSR-LGATLAVIDSEK-DM--IFLKRYV
G-----RTDHWIGLKKE-A--DQSWKWSNGK---EFN-----NW-----------FNFTG
SENCAFL---NSA--S------IG-----STECER-N--LHWICSKPSKE----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MLKPPDIQHSLP-LK--DFMMRFQ
G-----LANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W---SLRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKAHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------GASPEPPARAR------------------
------------P-----PPPVAA---------------------DPRPRPPLPP-PGR-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHS-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------T--
-------------------TN---------IFTVCVVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MSA
AE----------------------------------PAEATVG-----------------
-------------------------------MLST---TDILQE-GE----LGK------
---KLERKCLRII-------SPV-----SPTRPYCCYAVI-IILTV-AVIALSVALSL--
----------------SV-RRRE------------QDSIK----------KLHAPCPRD-
WIGFGNKCFYFSED--T---SNWTFS---RNFCME-LEAQLARFDNMK-EL--NFLRRYK
G-----TFDYWIGLHRELP--QHRWRWMDNT---EYN-----SS-----------VPIRG
AEEYAYL---NNN--G------IS-----SARIY-AD--RRWICSKPNNYILE-CQIPFA
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------IIAVYVVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------TITVYIVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCFT-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

MERV---WEVAPGGQAGAEVP-MEPVGSLVPGLEQAQVPEK----ARQPEGPESSPSPA-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPPLSLGYGVC-------PEPP--
------------SPGPASVKLPRNGEAPGA----------EPAPGAWAPMELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQADPSQ--
---QLLLRTSSLGGTWGRGSTLAAAGTESGRDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--EGEEKLPRAVTLTG-LPMF-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QACPPG-
WVLSKEHCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGKD-----NL
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MK--EMREY-PGFLGTERS----------QRGGS------
----S-LEMKPGARVACRVT----------MA----VAF--LVLLV-TAIAFAVN-----
-----------------------------------AFQPRPQP---------CARCPFD-
WIGYRGKCYYFSEA--E---RNWTSS---QDNCSA-LGASLAMFDSVE-DL--SFTMRYK
G-----ISEHWVGLSRD--GEEQPWKWVNHS---RP------SP--------L--FQVQG
GGFCAYL---GDT--G------LH-----SSQCST-E--RNWVCTKPALNSPDKGNKTRR
ARN----LCISS--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTASQSQNDYRPQQEA----S
--------SSRL------------------S-LSCRVAIA-LGLL--TAILTS--LLL--
YQ-------------WIRGQG--------KLPRS----TCASC----------PSCPDL-
WMRYGSHCYYFSVE--R---KDWNST----------KDAHLLMFTDTQ-EM--SLLKDFV
D-----KDFHWIGLRDT-----SGWRWEDGS---ALNYSRILS--------------NSL
VQKCGTM---NKN--G------LQ-----ASSCEV-P--LPWICKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SAIY
YTL----------------------------------ELPAAPQVQDESGRKPKA----V
--------LPRP------------------RRLSCLVTVA-LGLL--TMILILMSLLM--
YQ-------------RILCCG--------SKD-S----VCAHC----------PSCPNF-
WMKNGSHCYYFSVE--K---RDWNSS---LEFCAD-KGSHLLTFPDEQ-EV--IPFRELL
G-----TDFYWIGLRNN-----GSWRWEGGP---VLS-LWIAS--------------NSV
IQRCGAI---NRA--G------LQ-----ASSCEV-P--LQWICKKAIH-----------
--------------------------------

MERA---KDAAPESQAGAELP-MEPVGSLLPGLEQPQVPAE----MRQPEGRESSLTPA-
--------GAVEEAAGAGREPSSEKQLPSPLPGPLRVPPLSLGYGAC-------PEPP--
------------SPGPAAAEPSQNSEAPGA----------QPAPGAWAPIELQVDVLVKP
VGAASGSRTPSPRPSTR-----FL--------------K--VPVPESPAFSRSAAPAH--
---QLLQRAPSPGCTWGRGSPLAAARTES--------TPAEGSAGSPSSPTC---CRCK-
-------ELGLEKEGAALLPC----AGL--DRDKKLPRAVTHLG-LSVY-----------
---------MKSL-------HRALAVMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGTRC-------------QPCPPG-
WVLSEEHCYYLSAE--A---QGWEAS---QAFCSA-YHATLPLLSHTQ-----DLLSRYP
V-----SKHSWVGAQRG----PQGWHWIDGA---PLP-----PQL-LPEDGEN-----NP
DINCGALE---EG--T------LV-----AANCST-P--RRWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MPWCPDG-
WLGYQGKCYYFSEA--E---LSWNDS---RTNCSV-FGASLAAIDSEQ-QL--AFMMRYK
G-----ISEHWIGLWKEQE--GKQWKWVNGS---DFD-----SP----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ME-EL--NFRKRYK
A-----PSNHWIGLRRESS--HHIWRWMDNT---EYN-----NT-----------LAIRG
GGECAFL---NDN--G------V--------RIF-ID--RKWICSKPNSYVCS-CQLCPH
WDPT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------LEAAGCLPARPPASRAR----PP-A
A------------------------------------------------PPAPRC-PLP-
------------------ARSP-----G----RWGPWG------------GGGWG-G--A
GR----GGAGHSR-----P--SLS-SDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLFGRKCYFFSEE--P---RDWNTG---RQYCHS-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FSISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------VDVRVKS
VGAAGSSCAPSPAP-TR-----FL--------------T--VPVPESPAISHHASPAH--
---PL-RLTPSPGGTWGRGTPLAAARTERDLDAEGWAGPAEGRAESPGSPTCRCRCKET-
-------PL---------------HAEM--DGDKKLSRVIKLVG-LPMY-----------
---------MRSL-------RWALAVMAVL--------L--AVSTV-----AIVAL----
--------------------------------ASRAXXXX-------------XXXXXX-
XX-XXXXXXXXXSA--A---EAWEAS---QAFCSA-HHATLPLLRHTQ-----DFLSRYP
V-----TKYSWVGARRG----PQGWHWIDGT---PLP-----LQL-LPEEDQQ-----EP
DLNCGGLE---GG--K------FV-----ASDCAS-P--RPWVCARGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------CKLKQNW--------KIGFACFL---ILI---VIILST------
---------------------------------HIVKYSKCPT---------TMACLGD-
WIKVEEKCFNFSDD--T---KNWIEG---KRFCSS-QGSELTHIDIHT-DM--EFLKNRI
G-----IFMHWIGLSRK-P--GKQWK-TNDT---IFN-----G-----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SI--------------TETS-------------SSHL-----------ERGQKD----H
GTSIHFEKHHEGS----------IQVPIPCAVF---TVFIITSLII-ALVALSVGQ----
YN----CPGLYQ-----------------------NLASLDHR---------VASCQDE-
WVAYQRKCYFFSTA--T---SSWALA---QNSCSR-DDATLAVIDSEK-DM--IFLKRHA
G-----RQEHWIGLKNE-V--NQTWKWANGK---EFN-----RW-----------FNLTG
SERCVSL---NST--D------IA-----TEDCEK-N--LHWVCSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRADGF------
---------IHR--IVPKLIQNW--------KIGL-MCF---LSII-ITTVCII------
---------------------------------MIATWSKHAK---------PVACSGD-
WLGVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKAELAQIDTQE-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----GW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PKYFL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MPSS--AHLQDPPPLLSRTLTQN--
------------------------------------EGQTSLR------------QSSS-
CG------LS------AASASE--SLSGS------------TESRIP----HSE------
---MLQEKFHGII-------LPE-----SPAKLLCCCAVI-VVLSV-AVVALSVALSV--
----------------K---KTP------------QISTV----------KTYAACPRN-
WIGVGNKCYYFNET--A---RNWTFS---QTLCKE-QEAELARFDTEE-EL--NFLRRYK
G-----SPGCWIGLHRESS--AHNWTWTDNT---AYN-----KL-----------LPIRG
VEKHGFL---SDN--G------IS-----SSRDY-IK--RNSICSKLNSYTSQ-CQ----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------SCLDD-
WIGYLGKCFYFSEN--T---TTWAAS---QNFCTS-YAATLAVFNTTK-EL--DFLKRYS
D-----HSQYWIGLSRK-P--GQTWKWIDGT---TYS-----GW-----------FKIIG
IGECAYL---HKI--G------IS-----SASTHL-V--RKWICSKPDTHI---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MFLA-----------V-----
-------------------------LCLY-LILKMFFN----------NLFPDY------
---------------LHSKE-HCSKATLNWCLFFLIVF----L----TITLCG----MT-
---------------I----------TLRAIRTNCHQKPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDANLALVENFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--DQPWKWTNGT---EWT-----RP-----------FPITG
EGECAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMIQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------GK------
---VLQGKLLRSI-------SPE-----SRVKLHCCYGVVIVVLTVA-VVALSVALSV--
----------------SVRNKIP------------VMENCE---------PCSATCPSG-
WIGFGSKCFYFSED--V---GNWTFS---QSSCMA-LDSHLALFDSLE-EL--IFLKRYK
G-----PSDHWIGLHRAST--KHPWIWADDT---EYS-----NL-----------VLIRG
GGQCGFL---SDN--G------IS-----SGRDY-TH--RKWICNKSSSYT-SQYPLFVN
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MLRDQRE------
--------------ERRDVGVILEHLKKKWILILVSIVI--IILSI-TIIALAARQ----
------------------------------SPPCPS--CLPPV---------AAACPDG-
WVGFQGKCFYLSET--E---GNWSTS---QNHCAS-LNASLATVDSLP-EL--AFMLRYK
G-----VPFCWIGLQRE-QDQGQPWKWTNGT---IFN-------N-------L--FEIRG
EGQCAYL---DER--G------VS-----SARCYS-D--RHFICSQPDECSR-RKLSAAR
GDT-------MSKIT-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRADGF------
---------IHR--IVPKLIQNW--------KIGL-ICF---LSII-ITTVCII------
---------------------------------MIATWSKHAK---------PVACSGD-
WLGVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKAELAQIDTQE-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PKYFL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-HC--
-YV--------------TENS-------------SLHP-----------ESAQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSVPSDSH---------VSSCSDD-
WVSYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNFTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYKS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPAR----------
------ARAPP-P-----VPARPR---------------------PPHRPRRPRR-PGS-
------------------LARR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------LRIF-------SPE-----SPAKLYCCYAVI-LVLTV-AVVALSVALSV--
----------------K---KTP------------QISNI----------NAYAACPRN-
WIGVGNKCFYFSEY--A---SNWTFS---QDFCKA-QESQLARFDNQE-EL--NFVKRYK
G-----SSNYWIGLHRESS--EHPWKWTDNT---EYN-----NL-----------VSIRG
DELLGFL---SDS--G------IS-----SSRNY-IK--RNWICSKPNNYTSQ-CPQPQP
S-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------S-----
-------------------------NNVE-KDIAPSEL----------PANPGY------
---------------RHSKE-HSSKATLIWPLFFLIMF----L----TIIVCG----MV-
---------------V----------ALSAINANCHQKSSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQQWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMLQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-EC--
-PT--------------TETS-------------SLHQ-----------EKGKK------
-----------------------------------------------------MGK----
YN----CPSWYE-----------------------LSLPSNSH---------VSPCPDA-
WVLYRRKCYFFSTT--A---KSWTSA---ESSCSE-DGATLAVIDSEK-DL--IFLKRYA
G-----SAEHWIGLKNG-T--GQIWKWSNGK---EFN-----HW-----------FNLTG
FESCASL---SST--E------VG-----SAECGQ-G--LPWICSRASR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MTA
TE----------------------------------TSQKMLK-----------------
------------------------------IDLTF---RDGLEE-GE----SGK------
---TLQRKCLALM-------SPV-----TPVKVYCCLFII-AVLTT-SVVALSIVLSV--
----------------LV-REEK------------PVMES----------PKYAACPKS-
WIGFGSKCFYFSED--T---RNWTFS---QVFCVS-LEASLAQFATME-EL--NFLKRYK
G-----PSDHWIGLRRESS--DGIWRWTDNT---EYN-----NT-----------FPIRG
VGQCAYL---NDN--G------VG-----SASIY-TH--RKWICSKPNSYVYS-CQ-IRN
SLPNFPMDVS----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEGEE--------------
----MENRRKRRVQ-V--QRKMII----LSVLLCGGLAV-----LL-W----MM------
---------------LKFPKK-------MGIKI--IKKNCTND---------LRVCPPG-
WELLSQKCFFQSEN--E---GTWSEG---QRHCRK-YLGSLAKIVSQA-EM--KSVAKHL
D----K-STYWIGLRKHLS--DNIWRWMDGS---HFN-----NW-----------FRVSG
SGNCAFV---DTT--G------GS-----VTSCDG-K--RRYLCSRKSECG---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MLD-------------NAIY
SNT----------------------------------EFSTAYRDQNDFRGQQK------
----A---SSRP------------------S-LSCQVAIG-LGLL--TVILVS--LLL--
YQ-------------WILFQG--------SSH-S----ACTNC----------SSCPDL-
WMGYGNHCYYLSVE--K---KAWNSS---VEFCLS-KDSQLLMLRDDQ-EM--NLHKNFL
S-----NDFYWVGLRNN-----SGWKWEDGS---ALK-SRIIT--------------NSL
VQMCGVI---SKT--G------LQ-----ASSCEV-S--LQWICKKARL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MAEPFPAPR-GD----------GARGDEERQSQR-------DPPRSLREVLAMKSA
PPAPLCPQPG-PS-----L-----PL----------SPHTMGA-----------V-PHL-
-HG--------------AMEER--ERR------SPSPPR-------EATTREGD------
----EERQSQRGS-GCSKLRQNRRC--VLCVALCAVLCI--LVSVV-VAVI---VL----
--------------------------------QRPSCPPRPPF---------SHVYPNT-
WVGFHGKCYYFSDT--K---SDWKSS---REQCHR-LGASLATVDREE-EM--EFMRGYR
R-----PADRWIGLHRA-E-GDEHWTWADGS---AFS-----N---------W--FKPQG
GGQCVYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVL--------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREP-------------
---PARARPPPPA-----ARPA-----------------------PAAPRPRS---PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
TGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-VSYQGKCFYFSEG--E---GNWTYS---RSRCSA-LGASLAGIDTLK-EK--DFLLRHE
G-----ERGYWIGLRRD-L--GQSWKWANGT---EFN-----NQ-----------FEIRG
DGDCAYV---NK-N-G------IS-----SWRCTS-E--GHWMCSKSDALTAAKETPEGG
GL------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MQSVQIPVLKHKVST----------PAEGERLNHFSEH--KAAPEPPAHQRRRIPTSSD
PQ---LPEED-VQ-----ISLLESNT----------STHTMGE-----------G-DQQ-
-E-------------------------------TFSEPK-------AAPEPLGQ------
----SGEGPQWGS-RCHVTGRRRSR--VQLIAVCAALGT--LSLVL-VV--ILTAR----
--------------------------------WPVPVPPFPAF---------GHACPNA-
WVGFQGKCYYFSEE--E---NDWNSS---REHCNA-HGASLATIGSAE-EM--DFMMRFQ
G-----PANCRIGLHRE-E-EDAQWTWHDAT---AFT-----N---------W--FELRG
GGRCAYL---NRG--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKVHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MMIENVYRAS------------HTS-----
----HVLGHQRTTF-D--GKKLLT----LWTLLCGGVVV-----LL-W----GF------
---------------FSFPRK-------FGASRVVRNKTCDDE---------TNICTNS-
WLKINQNCFFLFQH--K---NAWLSA---QENCQR-YEANLAKFTTKT-EL--ETLMSHV
QA---LRSSFWIGLNRRNL--RTYWVWTDES---VYN-----NL-----------KKVQD
HGDCAFM---HKN--G------ID-----STNCDD-L--RDYICSKVGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MIE-------------NDIY
SSA----------------------------------QITTAPQTQRDYRPRQND----S
---------LWS------------------P-LFRLVVIP-LWLL--AAVLLS--LLI--
YK-------------WSLCIG--------S--------SCASC----------PSCPDF-
WMKHGNNCYYFSLE--K---KTWNSS---LEFCLA-NDSNLFMLTDSK-EK--QLLKNIL
N-----FNFYWIGLRKN-----LNWRWLDGS---AIDSSRIFT--------------NSL
VQNCGAI---NQD--G------IH-----ASSCEF-P--LQWICKKSFADK---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MNAA---------------------
----------------------------------------KVE------------TSSM-
GML---Q------------RAD--LT------------AADCLQEGE----MGK------
---KIQGKCFRII-------STV-----SPVKLYCCYGVI-MVLTVA-VIALSVALS---
-----------------VRNKIP------------AMEDRE---------PCYTACPSG-
WIGFGSKCFYFSED--M---GNWTFS---QSSCVA-SNSHLALFHSLE-EL--NFLKRYK
G-----TSDHWIGLHRAST--QHPWIWTDNT---EYS-----NL-----------VLTRG
GGECGFL---SDN--G------IS-----SGRSY-TH--RKWICSKFVSSCKSRVGSVPR
HV------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------PSS-------------SAIY
STL----------------------------------ELPTAVQVQDDYRPQRRG----G
GTTEL---NPRP------------------P-LFCLVVIV-LGLL--NILLTS--LLL--
YL-------------WIPGQG--------PSD-S----NRASC----------PSCPDF-
WMRFANHCYYFSVE--K---KDWNSS---LQFCIA-RDAQLLIILDNQ-EM--SLLQNLI
D-----QDFHWIGLRKN-----SSWRWEDGS---ALNFSRVYS--------------NSL
VQRCGAV---NKD--G------LQ-----ASSCEV-P--LRWVCKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------RRR--TICNFKPNW--------KICLCVCF---VI---IFAACII------
---------------------------------MIVKWPKCDK---------RVACSGD-
WLAVREKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DT--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYSS-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-HC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSDD-
WVSYQRKCYFISTV--K---RSWTSA---QSACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNLTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYKS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------PGT------
----HRGRHFSDNL------DGPLLVPVPCAV----LVLI-IIIII-IVPPLLIAVGK--
Y--N--CPGIWE------------------NQEPGKNVKCPAS---------PISCPDD-
WIGFRGKCYLLSNI--P---DTWNAS---KRFCSN-LNATLTKVESEK-DL--DFLKRLT
G-----TSEHWIGSISG-T--IQGLSWTTSN---LL------SN--------R--FLFPC
CSSCHYL---KGT--T------SG-----RKDCQE-S--LLGICSTSST-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------RRPR-A
VGPFELPAPPPPA-----VRPA-----------------------PAPAAPRPRS-PAE-
------------------AEGR-----S----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHS-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FPIAG
PGECVFV---EPT--R------LV-----STDCLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------KRR--TICNFKPNW--------KICLCVCF---VIII-IFAACII------
---------------------------------MIVKWPTCGK---------RVACSGD-
WLALRDKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PRYSL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MID-------------NDIY
SVW----------------------------------QWSTEPQAQNDYRPQPKV----S
--------SGRS------------------P-LSRHVAIA-LGFL--STILVC--FLL--
VQ-------------WILCQG--------SKC-N----TCTSC----------YSCPDL-
WMRYGNHCYYFSVE--K---KDWNSS---LEFCLA-EDSHLLMFTDNQ-EM--SLLKNFL
R-----KDYYWIGLRNS-----SGWRWEDGS---ALNHSSILS--------------NSL
IQKCGTF---SEA--G------LR-----ASSCEV-L--LPWVCERVRR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MWCYNLLP--GA---------AVKPDGADPRPSA---------ASCCPEG-
WIGAGGNCYYFSED--E---RNWETS---QNYCSV-HAASLAANDSLE-TL--NITLHRK
G-----PSNHWVGLRRE-P--GQPWRWVDGA---AFN-----HPLTSPLEPHS--FAIRG
AGLCAYL---ADG--V------VS-----SAGCDT-E--RKWACSKPHGRIGASPEDAEC
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------M--
P---------------------------------PSAVLGSPV---------LLCCPHG-
WVGYKGKCYYFSEG--E---GNWTDS---WSHCSA-LGASLAGINTLQ-EM--AFMHRYK
G-----KPDHWIGLQRD-P--EQPWKWANGS---KFN-----NL-----------FGIRG
GGDCAYL---NDES-G------VS-----SSRCTN-E--RRWICTKPDAFPTSEPRATTP
ASA-----F-----------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------L----
--------------------------------FPAASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FPISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

MEQA---WEAAPGGQAGAELP-MEPVGSLVPRLEQPQVPAK----VRQPEGPESSPSPA-
--------GAVEKAAGAGLEPSSKKKLPSPRPGSPRVPPLSLGYGVC-------PEPP--
------------SPGPALVKLPRNGEAPGA----------EPAPSAWAPMELQVDVRVKP
VGAAGGSSTPSPRPSTR-----FL--------------T--VPVPESPAFSRHADLAH--
---QRLLRAPSQGGTWGRRSPLAAARTESGCDAEGRASPAEGSAGSPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--DGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QQCPPG-
WVLSEERCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWQG----PQGWHWIDEA---PLP-----PQL-LPEDGED-----NL
DINCGALE---EG--M------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------G--------SKY-S----TCAHC----------PSCPDL-
WIRYGDHCYYFSVE--T---KNWTSS---LKFCLG-KDSHLLMFTDKQ-EM--NLLKSFL
N-----EKFYWIGLRNN-----SGWRWEDGS---TLNFSRILS--------------NSL
VQKCGAI---SGN--G------LQ-----ASSCEA-P--LHWVCKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MFSFIRCSL
LQQEEGAEPPSPECSE-----------TGENGPYSMPSS--AHLQDPPPHLSGTLTQD--
------------------------------------EGQTSLR------------QSSS-
CGP---SA---------ASASE--SL------------SGSTESRIP----HSK------
---VRQGKGLRSI-------FPE-----SRVKRYCCYGGVITVVAIAIVVPLSVTLSV--
----------------KQMEQTSINNTFAASINNTSAASIN---------NTSAACPSN-
WTEYGNKCFYFSEY--T---SNWTFS---KDFCAA-QGAELARFDTEE-EL--NFLKRYK
G-----SSGYWIGLHRESS--EHPWKWTDNT---QYN-----NL-----------VPIRG
DGQCGFL---SDQL-N------IS-----SSRVY-VE--RPWICSKPKKYISQSQ-----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------SD-----
-----------------------------------KDIPACPS---------LELCPSD-
WLYFQKKCYYLSER--E---ANWNSS---QNFCSL-RNASLLVIENLQ-EL--SFMVKIT
------KQDPWIGLHKI--NEEF--FWVNGS---TLD-----NK--------L--IEVKG
SGNCAYL---ESK--G------VS-----ASGCYL-T--RKWVCSL--------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------A-----AR-------------------------PALSAPRPRS-PGE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------G-LPMY-----------
---------LKSL-------RWALIVMALL--------L--AVSAV-----AIVAL----
--------------------------------ASRAGARC-------------RPCPQG-
WMWSEEHCYYLSAD--T---QAWEAS---QAFCAA-HHATLPLLSHTQ-----DFLSRYP
V-----TKYSWVGARRG----PQGWHWIDGA---PLP-----PQL-VPVEDED-----EP
DLKCGGLE---RG--K------LV-----ALDCTS-P--RPWVCAKGTE-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------KIMQGC---------ESCCPHN-
WIGYQKKCYYFSEE--E---RDWNSS---SKSCTP--QATLTTIDNKE-EM--QFLMHNK
G-----SSDHWIGLKMT-K--YQTGEWVNGT---IFN-----NW-----------FPVKG
DGGCAYL---SDN--G------VA-----TARCYNAV--RKWICKKNMS--I--------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---PADARAPPPA-----PPPXPPPV-ARPAPA------------PAAPRPRSP---GE-
------------------AEAR-----G----PEVLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EGGYWKVCL-GLR----VVVFFFFQ----FL----
--------------------------------LILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--L---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FSISG
PGECVFV---EPT--R------LM-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----A
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--E---KDWNSS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFRWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAL---NKN--S------LQ-----ASSCEV-P--LQWVCKKVRP-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MVG----SMILNFI-L---------IILLS-ALVRRD
---------------------------------KREEGPLLSP---------GDLCPSG-
WIEFQRKCYYFSED--E---GNWASS---SLYCSS-HNASLAVIDSQE-EM--KFLLRYK
S-----PPDHWIGLRRDNP--EQLWRWINGT---IFH-----VW-----------TTVQG
RGRCAYM---NHK--A------IA-----SSSCSR-E--EHWICSKPAESYQFVTT----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MIAA---------------------
----------------------------------------KSE------------EASK-
GLL---K-------------TD--LI------------TPNSLQKVE----IGK------
---KLQGKCLRII-------FTE-----SPVKLYCCYGVI-AVLTAA-VLSLSVALS---
---------------------LP------------VMGKCG---------PCYNTCPKD-
WIGFGSQCFYFSED--M---RNWTFS---QTSCME-LEAHLAVFESIE-EL--NFLKRYK
G-----PSDHWIGLHRKSA--EQDWMWPDNT---QYN-----NM-----------VPTRG
DGECSYL---SDI--G------IS-----SARVY-TH--RKWICSNSQDFK-WRIGNVPK
PS------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MGTKQG-
WMWSEEHCYYLSTE--A---QAWEAS---QVFCST-HHATLPLLSHTQ-----DFLSRYP
V-----SKHSWVGAWRG----HHGWHWIDGA---PVS-----PQL-LLEDDED-----RP
DPQCGGLE---EG--K------LV-----ALDCAS-P--RPWVCAKGAK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPAR----------
------ARPPPP----------------------------------VAARPAPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGK-----------G-E---
---------------------Q--KTDKP--DNL--LPV------PGDVEKGAK------
---S--KPAFHIF-YTSSPKGTAAVKFSVCILL---LII--LVLVI-SLAVVASRV----
-------------------------------------PEPLLV---------KLTCPDD-
WVGYRGKCYYFSEA--E---ETWDSS---RSHCSA-LGASLAGIDTLQ-DL--VFLMRHK
G-----RDYHWIGLRRE-D-EAQPWKWANGT---EFN-------N-------L--FHVTE
GENCAYL---NDV--A------VY-----SSKCSS-M--KKWVCSKPSLHLRKE------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MT------------------
------------------EEIR--EREGR--NSGSEWLN----PESDDTTHPQ-------
---------VAGAREVTNAALIPKCITDKKYALAAAVVV--TALII-TIISLAVRK----
------------------------------QQPCPV--CPPPV---------DAACPDG-
WVGYQGKCYYRSDS--E---KNWSSS---ANHCST-FGAFLAVFETQQ-VL--AFLVNFT
R-----PLHYWIGLSKT----GDTWRWPNGS---EFK-------K-------Q--SLVRG
DGECAYI---NDI--G------LS-----STRCTA-N--NLFLCSQDDACIRKKKHSTT-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTQ-----------SRQVA-
---------APAQGGPE----------ND-NSNQ----G------KETQKKQGI------
---------------KNMKE--------K---------C---ILIF-IGLVLG--I-V--
-------------------LT---------ILYFSICLKGTET---------QHFCPHD-
WIGFQDKCYYFSKE--E---GDWNSS---RYNCST-QHTDLTMIDTVE-EM--HFLRRHK
C-----TSDHWIGLEMT-E--NQIRKWVNGT---VFN-----KW-----------FTVRG
NEKCAYL---NDD--G------VA-----TARCYT-E--RKWICRKKVH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MRD-------------SVIY
SML----------------------------------ELSTATRARNDYRPQQKA----S
--------SSRS------------------S-ISCLVTVT-LGLL--TAILMS--FLL--
YK-------------WILCQG--------SNY-P----TCARC----------PSCPDL-
WMRYGNHCYYISAE--K---KSWNSS---MEFCLA-KDSHLLMFTDNQ-EM--SLLKNSL
N-----ENFYWIGLRND-----SGWRWADGS---VLNLSRVIS--------------NSL
VQNCGAV---NKD--G------LQ-----ASSCEV-P--LQWVCKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------V------STCGLWGHG------
---------CKQ--WISMLKQNW--------CKCGLVCI---V--------ITI------
---------------------------------VATVCLKHSK---------TTACPSD-
LIGVGEKCFYFSND--T---GDWEAS---KRFCQS-QGSELARVDTQT-DM--EFLKKHT
G-----TAMHWIGLSRR-L--GESWKWTDSS---TFT-----D-----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MEMAD-------------SVIY
SIL----------------------------------ELSTGTQAQSGDRPQQKA-----
--------SSRP------------------S-LSSLVAIA-LGLL--AAVLAS--VLL--
YQ-------------WISCQG--------SNP-S----TCVSC----------SGCPDL-
WMRYGNHCYYFSVE--K---KDWNSS---LRFCLA-EDSHLIMFADDQ-EM--QLLNRFL
N-----QDFHWIGLWKN-----DSWRWEDGS---VLNFSRIIS--------------SSS
VQKCGSV---NMY--G------LQ-----ASSCEV-L--LQWICRKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------K------
---SLKRKCLRII-------SPE-----HPAKLYCCYAVI-IILTV-AVIVLSVALSV--
----------------GE-RSQQ------------QSSIK----------KTYAACPRN-
WIGVRNKCFYFSED--S---STWTLS---QKSCLE-QKAQLARFDNME-EL--NFLKRYK
G-----TSDYWIGLHRESP--EHPWRWMDDT---EYN-----NS-----------VPIRG
VEDYAYL---NNN--G------IS-----SARIY-AD--RRWICSKPHSYILQ-CQIPFV
SF------------------------------

MERA---WEAAPGGQVGAELP-MEPVGSLVPGLEQPQVPAK----APQPEGPESSRSPA-
--------GAVEKAAGAGLEPSSKKKLPSPRPGSPRVPPLSLGYGVC-------PEPP--
------------SPVPALVKLPRNGEAPGA----------EPAPGAWAPMELQVDVRVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRHADPAH--
---QLLRRAQSLGGTWGRGSPLAAARTESGCDAEGRASPAEGSAGSPGSPTC---CRCK-
-------ELGLEKEDAALLPC----AGL--DGDKKLPRAVTLTG-LPMY-----------
---------VKSL-------CWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QQCPPG-
WVLSEEHCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWINEA---PLL-----PQL-LPEDGED-----NL
DINCGALE---EG--M------LV-----AANCST-L--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPSR----------
------ARPPPPP-----LAARPV---------------------PVPAAPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDHGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SNY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWNSS---LEFCLA-RDSHLLVIMDKQ-EM--SLLQVFL
S-----ESFRWIGLRNN-----SGWRWEDGS---PLNFSRISS--------------NSL
XXXCG-------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MMNS-----------E-ND--
-FT--------------TENS-------------SLHL-----------ERGKEN----N
ATSVHFETHHEGS----------LQVPVPCAVM---NVVFITILII-TLIALSVGQ----
YN----CPSQYE-----------------------FR---------------VSSCPDD-
WVGYQKKCYLFPTV--T---KSWTSA---QDACSK-HGATLAVIDSEK-DM--IFLKRHV
G-----GTEHWIGLKNE-A--DQTWKWSDGK---QFN-----NW-----------FNLTG
SGNCAFL---KST--E------VN-----NRECEK-N--LHWICSKPCQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MNAA---------------------
----------------------------------------KVE------------TSSM-
GML---Q------------RAD--LT------------AADCLQEGE----MGK------
---KIQGKCFRII-------STV-----SPVKLYCCYGVI-MVLAVA-VIALSVALS---
-----------------VRNKIP------------VMENRE---------PCYTACPSG-
WIGFGSKCFYFSED--M---GNWTFS---LSSCVA-SNSHLALFHSLE-EL--NFLKRYK
G-----SSDHWIGLHRAST--QHPWIWTDNT---EYN-----NL-----------VLTRG
GGECGFL---SDN--G------IS-----SGRSY-TH--RKWICSKLVSNRKSRVGSVPR
HV------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-HC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------ASSCSDD-
WVSYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNFTG
SEKCAFL---KNM--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MLCRRGLE--E---NDWNSS---REHCSA-HGASLATIGSAE-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADLYVLWKQKAHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------PA-----VSQMAGIT-AVTLRA---GYSFCS---VPPIRLLRLG-LDM-
------------------VVGL-----G----PTAD--------------AVPFV-F--S
L-----DTTTR----------LLL-G---------AIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
MGECVFV---EPT--R------LV-----STECLA-T--RPWVCSKMAYT----------
--------------------------------

MERV---WEAAPGGQAGAELP-MEPVGSLVPGLEQPQVPEK----ARQPEGPESSPSPS-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPPLSLGYGVC-------PEPP--
------------SPGPASVKLPGNGEAPGA----------EPAPGAWAPMELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQADPAH--
---QLLPRASSLSGTWGRGSTLAAAGTESGRDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELGLEKEDAALLPR----VGL--EGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALVFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYFSVE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGKD-----NP
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

--------------------------------LEEPRVPAG----EPQADGPGS------
----------HQEPAGAGQDLAEDKLPPPPRPGPLRAQPLSLGYGAFRHLGSTSREPP--
------------SPGPMSAEQPRDGEGPGAELLPLAALGCEQAAGTWAPVELQVDVRVKP
VGAPGGS--PSPAPSTR-----FL--------------T--VPVPESPAFSRHASPAH--
---PLLQRAASPSAARGRASPLAAAAPTE-RDRTGAESPA------------------T-
-------PPGLEKEDA-----WL-RGAG--MDGQELPRAIKLIG-LPMY-----------
---------IKSL-------RWSLVVLAVF--------L--AVCTI-----TIVVL----
--------------------------------ASRAGAVC-------------QPCPQG-
WMWSEERCYYLSAE--A---QDWKAS---QAFCMA-HNATLPLFSHTQ-----DLLSRYP
V-----TKRSWVGAQRG----PQGWHWIDGV---PLL-----PQL--PKEDLE-----NP
DLSCGGLE---EG--R------LV-----ALNCSS-L--RPWVCVQGKQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DF--
-SA--------------TETS-------------SLHL-----------KREPQS----H
AAGTYSATYHEGS----------IQVPIPCAVV---NVVFITTLII-ALVALSVGQ----
YN----CPGQHV-----------------------SSAPPNIH---------VFPCSDD-
WIGHKGKCYLISKK--T---KNWTLA---QNSCSK-HDATLAVIDSKE-DM--SFLKQYV
S-----RAEHWIGLRNE-A--GQTWKWSNGQ---EFN-----NW-----------FNLTG
SENCAVL---NSA--E------VS-----STECDK-N--LHWICSKPSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MAD-------------RDIY
CTL----------------------------------ELPATPQVQEGSGSKLRA----A
--------LHRL------------------R-LSCLVTVA-LGLL--TV--ILMGLLM--
CQ-------------QILGCG--------SKD-S----VCAQ-------------CPIL-
WMRNGSHCFYFSME--K---KDWNSS---LEFCAY-KGSHLLTFLDDK-EV--IPFQEYL
D-----NDFYWIGLRKT-----DGWRWEDGP---VLS-LRILS--------------NSL
IQTCGTI---HRT--G------LQ-----ASSCEA-P--LRWICKKTIY-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRADGF------
---------IHR--IVPKLIQNW--------KIGL-ICF---LSII-ITTVCII------
---------------------------------MIATWSKHAK---------PVACSGD-
WLGVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKAELAQIDTRE-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PKYFL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------LN---------------VLLRNFSQKEK
SCFFFFPYDK-QR-----KYILC---------------HLLVK-----------YCHRKF
VRYGFERKLGLSFT-HFLIQVV--FR--------------------------FV------
----------SD--VNNKQYKHCKWR--LIFALAISVVI--NVLTN-IVIYFSVK-----
--------------------------------------EDRVA---------QYFCPDN-
WIGFQDKCYYFSEE--E---EDWNSS---RYNCLS-QNASLVMIATTK-EK--RFLKRFK
R-----TSDHWIWQDMT-E--NLTGQWVDEN---IHN-----K---------G--INMTE
NEICFYL---NED--G------VA-----TARCYT-E--RKWICRKKVH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------M---------VLSCPSG-
WVGYEGKCYYFSES--E---TNWNLS---QSNCSA-SGASLVTMENQK-EMLQDFIMQAK
G-----PTEYWIGLKRK-K--GQHWEWVNGT---LFN-----D-C-------Q--LDIGA
DGPCAYL---NDE--K------AS-----STLCGT-R--RNWICGMSA------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPSR----------
------ARPP-PP-----LAARPA---------------------PAPAAPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MGA
DQ----------------------------------PAEAFVG-----------------
-------------------------------MLGT---THRLQE-GE----MGK------
---KLQGQCFRIV-------SVE-----SPVKLYCCYGVI-TVLTV-AVFALSVALS---
-----------------V-RRSE------------QTPDK----------YTYAFCPRN-
WIGFGSKCFYFSEN--T---NDWTFS---QNFCKE-QEAHLAQFDSDE-EL--EFLKRYK
G-----AFDYWIGLRRESP--EHPWMWTDNT---QYN-----SS-----------VLIGG
VEEYAYL---NNN--G------IS-----SARVY-AD--RRWICSKPSSYALQ-CQIPFS
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------LSLPS--------------------------------SWNYRCRPPR-PG--
------------------------------------------------------V-N--G
G-----ILNLSLF-----S------PDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------H-T--FAISG
PGECVFV---EPT--R------LM-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFVV---GTAL-II--------I--
-------------------TN---------IITVYLVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-HC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSDD-
WVSYQRKCYFISTV--K---RSWTSA---QSACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNLTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYKS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------S-----
-------------------------KNVE-KDIAPSEL----------PANPGY------
---------------RHSKE-HSSKATLIWPLFFLIMF----L----TIIVCG----VV-
---------------V-----------FSAIRANCHQKSSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDANLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARCYT-E--RKWICSKPDTYVQMLQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------G-----
-------------------------NQLK-KDSEAVEL-----------TDSSN------
---------------LHPRK-HSITNTLNRLLVLCII------ILL-IIIVIAILVGLL-
---------------VT--G-----------RKLHRIS-SECL---------EAACPES-
WIGFQRKCFYFSDD--F---KNWTFS---QRFCDS-HGADLVQVETIQ-EL--NFLLRYK
G-----PYDHWIGLSRE-L--GQPWKLINGT---EWS-----NC-----------FPIRG
GGECAYL---NDK--G------AS-----SARHYT-E--RKWICSKPDTLFCWPARHHFS
VNT-------TSMFPGKISSPMDRVEI-----

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------IVTLKTPE---------TNPCLG--
-IETKEKCFNLYGE--T---KNWTAS---KEFCHS-KGSELAHIDTKE-EM--ELLKNHT
G-----TAMHWIGLSRE-E--GGPWKWTNGT---TFN-----D-----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-NC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSLPLDSH---------VSSCPDD-
WVGYQRKCYFISTV--K---RSWTSA---QNACSQ-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---DFN-----NW-----------FNFTG
SEKCAFL---KNT--E------IS-----SMECEK-N--VYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNLREF-EIRQ
VT----------T-------------CYTLVGQNWVPRARQHTASSPGGG----------
------VGD--------------------------------------PAVP-APL-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FNIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------TVLTV-AVIVLSVALSL--
--------------------KPE------------DDSNK----------KFFAACPRQ-
WIGIGNQCYYFSDV--M---RNWTFS---QIFCMA-QGAQLAQFDSLE-LL--AFLMRYK
G-----DFDYWIGLLRKSS--QHAWMWTDNT---EYK-----NV-----------TSPRG
QGECAYL---VGN--E------IS-----SGRNY-IQ--RRWICSKPQSFTA--CVVP--
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MEIMD-------------NGIY
FTF----------------------------------PLSTEPQTQNDCRPQQKV----S
---------PRF------------------P-LSHRVAIV-LGVL--NIIFVC--LLL--
VQ-------------WIHCRG--------SSR-A----SCANC----------CSCPDL-
FMKNGNYCYYFSLE--K---KDWNAS---LEFCLD-KDSHLLEFTDRW-EM--SLLLRFL
K-----NDFYWIGLRNK-----SGWRWEDGS---PLKISSIVS--------------NSL
IQKCGAI---NQH--H------LQ-----AASCEA-L--LPWICKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFHWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-S--LQWVCKKV-S-P---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------NVTY
SII----------------------------------KSSAARQALKDDRQQQEA----S
--------SSRS------------------P-RSYHVAIA-LGLL--STILAS--MLL--
LQ-------------WILYRV--------TQC-S----KCAGC----------PHCPDH-
WMGYGDHCYYFSVE--K---KSWNSS---LEFCLA-KDAHLLMFKDSK-EM--IELQNLL
S-----QEFYWIGLRNS-----SGWRWEDGS---ALNISRIAS--------------NSL
VQNCGTI---SKG--G------LL-----ASSCEV-D--FPWVCKKCLF-AELALT----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-DH--
-ST--------------TENS-------------SMHL-----------ETGRQS----N
ATSSHFATYHEGS----------LHVPVPCAVV---NVVFITILIV-ALIALSVGQ----
YN----CPGQYI-----------------------ASVPSDSH---------VSPCPDD-
WIGYQRKCYFISTM--T---SSWTSA---QSFCSK-HGATLALIDSEK-EM--VFLKRYV
G-----RTEHWIGLKNE-T--GHTRKWSNGE---EFN-----NW-----------FNLTG
SKNCAFL---NST--D------VV-----TAECQT-R--LHWICSKPSS-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MEGE------
------------------TELRCNYN--KCIVVLGVTVF---VLLI-AVIVL--------
-------------------------------AVGLSGHSPAAR---------GPCCPDC-
WLGYQGKCFYFSTA--E---GNWTNS---RSRCSA-LGASLAGIDTLQ-EM--AFLLRYK
G-----KPYHWIGLRRD-P--GQPWKWTNGT---KFN-----NL-----------FDIRA
DGDCAYL---NSEN-G------VS-----SSRCTG-E--RYWICSKPDVFTEKMEARNGS
VVE-----LAMGKLD-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------PA-----SRPA-----------------------PAAPRPRS---PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCQT-HEAALAVVQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FSISG
MGECVFV---EPT--R------LV-----STECLA-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNP-----------E-DC--
-SI--------------TETS-------------SLHQ-----------EKRKKN----N
ATSFRFETQHEGS----------LQVPIPCAVL---IVVFITILFI-TVIALFVGK----
YN----CPGQYE-----------------------VSMLSDSD---------VPSCSNE-
WILYHRKCYFFSTT--T---RNWTSA---RDSCSE-DGATLAVIDSEK-DM--IFLQRYA
G-----RAEHWIGLKNE-T--RQTWKWSNGE---VFN-----RW-----------FNLTR
YENCAFL---NST--E------VS-----STECEQ-S--LHWICSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SVI----------------------------------ELSTATQAQNDYGPPQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLTS--VLL--
HQ-------------WILYQG--------FNY-S----TCASC----------PSCPDL-
WMRYGNHCYYFSVE--K---KDWNSS---LQFCLA-RDSHLLIITSNQ-EM--SLVKGFL
S-----EAFCWIGLRNN-----SGWRWEDGS---PLNFSRIAF--------------NSL
VQTCGAI---NKN--V------LQ-----ASSCEV-L--LQWVCKKVRH---QTLF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------MVLSWV-WLGL--APSNLSLLVVPSPG-LPVY-----------
---------MKSL-------RWALAVMAVF--------L--AVSAV-----AIVAL----
--------------------------------ASRAGARC-------------QPCPQG-
WMWSEEHCYYLSTE--A---QAWEAS---QAFCST-HHATLPLLSHTQ-----DFLSRYP
V-----SKHSWVGARRG----RHGWHWIDGA---PVS-----PQL---------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MEQ-------ET----------EKEKKRLQ---VH--------------EDKKKH-
--------EK-QG------------------------KKKMKK-----------KKKEE-
---------EEEEEEEEEEEEE--EMEEE-DQKEENDSNYDAEEEDEGEDKGDEDDYNQE
GESTEEQEE--TES-PGGKSKKLI----FSTLVGGGIIS-----IL-LFVVSLS------
---------------KQ-VEK-------GT-VMNLEEQRCSDD---------STVCPKD-
WIRIFYKCYYLSSD--Q---KTWNAS---QKMCRS-LGASLATFNSIE-EM--EFLMKRI
G----S-SPYWFGLITENG--VSFWTWENGS---SIS-----RW-----------IWIKG
TG-CAHL---SRG--G------IS-----TDSCMS-Q--RNYMCSKVDKCF---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSA-----------E-DF--
-PI--------------TENS-------------SLHP-----------EGGQQN----N
AASPHFAAQHEGS----------LQVPIPCAVV---NVVLITVLII-ALIAISVGQ----
YN----CPGQYI-----------------------SPLPSNSH---------VSSCSDD-
WIGYQRKCYFISTE--K---KGWTLA---QNFCYE-QGATLAFIDSEK-DM--SFLKQYV
G-----TTNHWIGLKTE-D--GQTWKWSNGK---EFN-----NW-----------FNLTG
SENCAFL---NST--G------VS-----STACGK-N--LYSICSKPTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MSDCH----------PQCPQQ-
WVVYRGRCYSFSTE--K---KDWNSS---QESCRA-QGAHLLVISDTW-EM--DLFKRIQ
------AECFWIGLRNS-T--SSGWIWEDGS---VFDDAKVHS--------------NSP
VQNCAVL---MKD--Q------FR-----ASSCEF-L--APWICEKNP------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MPLFFS-------FTPRFLLEVFAKKSD
PLGPVYAQRD-PS-----L-----LL----------SPHTMGA-----------V-PHL-
-GA--------------AKEEK--ERL------SPSPPR-------EATVQPGD------
----EEVRAQRGS-RCSELRQNRRR--VLCVALSAVPCI--LVSAL-VAVI---VL----
--------------------------------QRPSCPPRPPF---------SHVCPNT-
SIGFQGKCYYFSDT--E---SDWNSS---KEHCHH-LGASLATIETEE-EM--EFMLRYR
G-----PANCWIGLHRA-E-GDEHWTWANGS---AFT-----N---------W--FELRG
RGQCAYL---NGD--R------IS-----SALCHN-E--KFWVCSRADSYVRWRKKALLV
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------L------
---------------ISKYS--------G------ILFH---LALN-ICIC---------
---------------------------------SFTVLAFRST---------QDSCPDD-
WIGFRNKCYYFSEE--E---GDWNSS---RHNCVT-QRADLTVIDTEK-EM--EFLIRHK
C-----SSDHWIGLEMT-E--NQTGRWVNGT---IFN-----KL-----------FPLRG
NEKCAYL---DDV--G------AA-----TARCYT-E--RKWICRRKMH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ME--EVREY-PHVLGTEWS----------RREGP------
----S-----RGACVTFQLT----------MA----AVF--TVLLI-TAVAFAVQ-----
-----------------------------------AFQPHPQP---------CAQCPFD-
WIGFRGKCYYFSED--E---SNWTSS---QNNCSA-LGASLAVFDSAE-DL--SFTMRHK
G-----SSPHWVGLSRE--GKEHPWEWVNRS---PL------SH--------L--FQVQG
DGLCAYL---GDA--G------LS-----SSHCSA-R--RNWVCTKPALQKPRKN-----
-------FCIST--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MEGSRAEQSDGTDGMPA-----
----MEQKVTRPGI-V--TKKMLV----ISS-ICGGIAL-----LL-W----VM------
---------------LEFPRK-------FKKPEILNDNTCSED---------ETICPQD-
WNQISNNCFFQSER--A---KTWIEG---QENCIA-YRGSLAIFNSKN-EV--EMLMPHL
G----T-SAYWIGLKKLNA--STPWMWVNGD---AFS-----NW-----------FNIEG
SGMCAFM---LHK--R------IN-----STNCDN-T--MKYICGREPRCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLLS--VLL--
YQ-------------WILCQG--------SNY-S----TCASC----------PSCPDR-
WMKYGNHCYYFSVE--E---KDWNSS---LEFCLA-RDSHLLVITDNQ-EM--SLLQVFL
S-----EAFCWIGLRNN-----SGWRWEDGS---PLNFSRISS--------------NSF
VQTCGAI---NKN--G------LQ-----ASSCEV-P--LHWVCKKVRL-----------
--------------------------------

MEGARAARGASREDRAGAELE-MESLGSQVAELEQQQDSAE----ERRPESPENSLS-LA
--------P-AKEAAGAGQDLSGGKMLPSPRPAPLRLLPPSLGYGAFRRQASTGPEPP--
------------SPDPVAAEQPRDGEMPETELIPKAAPG-EPAPGAWTPVELQVDVRVKS
VGTAGGSRAPSPAPSTR-----FL--------------T--VPVPESPGFSRHASPAH--
---TLLRRTPSPGGTWGRDTPPAAAGTERGLDAEGCARPAEGRAESPSSPVCRCRCR---
--------------EDAVLLPH---AEL--DGDKKMSRIIKRVG-LPMY-----------
---------MRSL-------RWALAVMAVL--------L--AVLAM-----AVVAL----
--------------------------------ASKTGIRC-------------RPCPQG-
WMWSEGHCYYLAAE--A---EAWETS---QAFCSA-HHATLPLLRHTQ-----DFLSRHP
V-----TKYSWVGARRG----PQGWHWIDGT---PLP-----PQL-LPEEDQD-----QP
DLECGRLE---GG--K------LV-----ASDCSS-P--RPWVCAKGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------CPNG-
WIGFQRKCYYFSEA--E---RNWTAS---SLHCSS-HNASLAVIDSQE-EM--AIASSSC
S-----REEHWI------------------------------------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRADGF------
---------IRR--IVRKLIQNW--------KIGL-MCF---LIII-ITTVCII------
---------------------------------MIATCSKHAK---------PVACSGD-
WLGVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKAELAQIDTQE-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------PSNS-
----------------------------------------KWSCNRRLPQWLLLLGPLR-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MC-
------------------------------------TAEASVG-----------------
-------------------------------MLST---TDRLK--------EGK------
---NLQGKCLRII-------SPE-----SPAKLYCCYTVI-ALLTA-AVIALSVALSV--
----------------K----KE------------QVSIK----------NTYAVCPRD-
WIGFGSKCFYFSEN--T---NNWTFS---QTFCME-REAQLARFDSLE-EL--NFLMRYK
G-----TFDYWIGLRRNSP--EPPWRWTDNT---EYN-----NS-----------VPVRG
VEEHAYL---NNN--G------IS-----SARVY-AD--RRWICSKPNSYTLQ-CRIPFS
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------IFTVFVQLLV--
--------------------RRR------------ELDSH----------VLHVPCLKG-
WIGFGSKCFYFSED--T---RNWTFS---QTFCTS-LEAVLAQFETKD-EL--NFLIRYK
G-----PFDHWIGLHRESS--HHVWQWTDNS---KYN-----AS-----------FAITG
DATCGYL---NDL--G------VS-----SARSY-TD--RKWICSKQIMSPCP-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------IG---------------------K------
---DLRKKCLAII-------SPV-----TPAKLCSCILII-FILLALNVVMLSALVAA--
--------------------RSR------------KPELK----------VLYVTCPEG-
WIGFGSKCFYFSEE--S---KNWTFS---QTSCTK-MEAVLAQFEMEE-EL--NFLKRYK
G-----PSDHWIGLSRESS--HHAWKWTDNS---KYN-----AS-----------FVITG
DGERGYL---NDL--G------VS-----SARSY-TD--RKWICSKQIMSLNSSRPF---
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------CFPHFIP--------------------LLA
LL----------------------------------TITGRLS-----------------
--------------------------RGN-IR---------------------K------
---DLRKKCLAII-------SPV-----TPAKLCSCILII-FILLALNVVMLSALVAA--
--------------------RSR------------KPELK----------VLYVTCPEG-
WIGFGSKCFYFSEE--S---KNWTFS---QTSCTK-MEAVLAQFEMEE-EL--NFLKRYK
G-----PSDHWIGLSRESS--HHAWKWTDNS---KYN-----AS-----------FVITG
DGERGYL---NDL--G------VS-----SARSY-TD--RKWICSKQIIYIVNSCSIACS
AK------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------CPP--CVPLSAPV-------TV-SFSVQRAK-----
-----PALAD----------------------------GCPPA---------GPLCPDG-
WVGYRGKCYSFSEG--E---GSWTDS---RSNCSA-LSASLAGIDTLQ-EL--AFMLRYK
G-----KPDHWIGLRKD-S--GQLWKWANGT---EFN-------H-------L--FRIRG
GGDCAYL---NDEN-G------VS-----SLRCTS-E--RRWICSKLDAFT-AAKQAAME
GANHRSVMEISP---GKT--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SAIY
SVL----------------------------------ELPTAPQAQNDFRQQQK------
----A---SSRP------------------S-LSCYVAII-LGLL--TVILVS--LLL--
YQ-------------WIVSQG--------SSY-S----T---C----------ASCPDL-
WMRHGDHCYYFSVE--K---KDWNSS---LEFCLA-KDSQLLMFRDNR-EM--NLCKDFL
S-----NDFYWVGLRNN-----SGWRWEDGS---ALN-FTXXX--------------XXX
XXXXXXX---XXX--XXXXXXXXX-----XXXXXX-X--XXWPFEDKLLLQ---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFHWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-S--LQWVCKKV-S-P---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-EC--
-SI--------------TENS-------------SSHL-----------ERGQRD----H
GTSVHFEKHREGS----------IQVPIPCAVL---VVVLITSLII-ALFALSVGK----
YN----CPGFYE-----------------------NLESFDHH---------AASCKNE-
WFSYNGKCYFFSTT--T---KTWALA---QKSCSE-DDATLAVIDSEK-DM--AFLKRYA
G-----GLKHWIGLRNE-A--SQTWKWANGK---EFN-----SW-----------FNVTG
SKKCVSL---NHT--D------VA-----SVDCEA-N--LHWICSKASL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MV-------------TGSKMHD-----------S-----
-------------------------NNVE-KDIAPSEL----------PANPGY------
---------------RHSKE-HSGKATLIWPLFFLIMF----L----TIIVCG----MV-
---------------V----------ALSAIRANCHQKPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDAALAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMVQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MAD-------------SSIY
STL----------------------------------ELPEAPQVQDESRWKLKA----V
--------LHRP------------------H-LSRFAMVA-LGLL--TV--ILMSLLM--
YQ-------------RILCCG--------SKD-S----TCSHC----------PSCPIL-
WTRNGSHCYYFSME--K---KDWNSS---LKFCAD-KGSHLLTFPDNQ-GV--KLFGEYL
G-----QDFYWIGLRNI-----DGWRWEGGP---ALS-LRILT--------------NSL
IQRCGAI---HRN--G------LQ-----ASSCEV-A--LQWICKKVLY-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------ALYNVF-F---LRSI-CLILLP--LKLQQ
LQFA---------------VR---------ADKRCPDLLPAVL---------ADSCPDG-
WVGYRKKCYYFSLT--E---GNWTVG---NIYCSS-HNASLAVIDSQK-EK--DFLLRYK
S-----PPDHWIGLQKD-S--GQPWRWVNGS---IFT-----GE------------LRME
EGSCAYL---NNK--A------VG-----SSSCRT-R--LYWICSKP-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEGEAIENTDGVEV-----
----VEQEVKRP------------------------------------------------
----------------------------VKNPKIFEDNTCSED---------ETICPKG-
WNQIRNNCFFQSEY--E---KTWIDG---QANCIA-YRGSLAIFNSKN-EV--ESLMPYL
G----P-SSYWIGLKKLNA--STPWMWANED---AFN-----NW-----------FKIEG
NGTCAFM---FKK--G------IS-----STSCDD-A--IKYICSREALCL---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VALFFI-------FPPRPLREVLAKKSA
PPAPLCPQPG-PS-----L-----PL----------SPHT-GA-----------V-PHL-
-HG--------------AKK----KDR------SPSPPR-------EATAREGD------
----EERQSQRGS-GCSELRQNRRR--VLCVALCAVPCI--LVSVL-VAVI---VL----
--------------------------------QRPSCSPRPPF---------SHVCPNA-
WVGFQGKCYYFSDT--E---SDWNSS---REQCHR-LGASLATVDTEE-EM--GFMLQYH
G-----PEDHWIGLHRA-E-GDEHWTWADGS---AFS-----N---------WSVFKPQG
GGQCAYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVLWRKGTNPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MKK-----------GKKEN-
---------AVAWKHNKKKVEH--EVKEE-KQEEEE------EQDDEKGRDGRED-----
---VVEVKV--PPR-ERRISKRLI----YSSVAGVGFII-----VI-ALAIFIS------
---------------KE-VRR-------KSEELIQEQPLCSDN---------SLMCPED-
WIKAFNKCYYISVD--H---KSWHES---QQACAN-LGANLARFKTHQ-EM--DFLMKRV
G----SASDCWFGLINEEG--NSSWKWTDGT---SPP-----EW-----------LQIQG
AG-CARL---SDD--G------IS-----SDSCMS-S--RNYICSKEDRCS---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------NVTY
SII----------------------------------KSPAAPQALKDNRRQQKA----S
--------SSRC------------------P-RSYHVAIA-LGLL--STILAS--MLL--
LQ-------------WILYRG--------SKL-P----TCAGC----------PHCPDL-
WMGHGDHCYYFSVE--K---KSWNSS---LEFCLA-KDAHLLMFKYSK-EM--IWLQNLL
S-----QEFYWIGLRNS-----SGWRWEDGS---ALNVSRIAS--------------NSL
VQKCGTI---SKD--G------LQ-----ASSCEV-P--LPWVCKKVRR-G---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------RRR--TICNFKPNW--------KICLCVYF---VI---IFAACII------
---------------------------------MIVKWPKCDK---------RVACSGD-
WLAVREKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DT--EFLKRCA
G-----TDMHWIGLSRK-H--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYSS-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MEELIQ
S-----PSNHWIGLRRESS--HHIWKWMDNT---EYN-----NT-----------LAIRG
GGECAFL---NDN--G------V--------RIF-ID--RKRICSKPNSYVCS-CQLCPH
WDPT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------E-
------------------AEGR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHS-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FPIAG
PGECVFV---EPT--R------LV-----STDCLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------PTIGE-----------G-DQQ-
-E-------------------------------TFSEHK-------AVTEPLGQ------
----S-------S-WCHGTGRRRSR--VQLIAVCAALGT--LILML-VV--ISTAR----
--------------------------------WPVPVPPFPDF---------AHVCPNA-
W----GKCYYFSKE--E---NDWNSS---REHCNA-HGASLATIGSED-EM--DFMMRFQ
G-----LANCWIGLHRE-E-EDTQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADYYVLWKQNAHPQ
--------------------------------

-------------------------------MTSSPQVPVE----APQAGVPDGNPRPER
--------TGREAADAELQVLSEEKPQPPALSGSPRLPPLSLGYGAFRRLGSCSRELP--
------------SPSPTWAELPQDGEVE---PQPWAATG-EPTPGSWAPVELQVDVRVKP
VGAAGASRAPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPTL--
---PRLPRAPSPGSTWGRGSPLAAPP-------TERIGPTEGSAVSPGSPTCRCRCRCQ-
-------EPGLTKEDAALLQR-----AG--MDSKKLPRAITLIG-LPLY-----------
---------MKSL-------RWALVVMAVF--------L--AVCTV-----VIVAL----
--------------------------------ASRGGARC-------------QPCPQG-
WLWSQEHCYYLSEE--A---QDWAGS---QAFCSA-HHATLPLLSHTQ-----DFLRKYQ
I-----TKGFWVGAQRG----PEGWHWTDGV---PLP-----PQL-LPKDSED-----HP
DFSCGGLE---EG--R------IA-----ALDCSS-P--RPWVCVKGAK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------GLL--TV--ILMSLLL--
YQ-------------QILCCG--------SKG-F----MCSQC----------SRCPNL-
WMRNGSHCYYFSME--K---RDWNSS---LKFCAD-KGSHLLTFPDNQ-GV--NVLQKYL
G-----KDFYWIGLRNK-----NNWRREDGP---ALS-LSILS--------------NSM
VQKCGTI---HRC--G------LH-----ASSCEV-A--LQWICDKCPTCYDTALH----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SI--------------TENS-------------SLHP-----------EGGQQN----N
ASRPHFATQREGC----------LQVPIPCAVM---NVVFITVLII-ALVAISVGQ----
YN----CPGQDM-----------------------SLFPSKSH---------VSSCSDG-
WIGYQRKCYFISTE--K---RGWTLA---QNFCYE-QDATLAFIDSEK-DM--SFLKRYV
G-----ITNHWIGLKTE-D--NQTWKWSDGK---EFN-----NW-----------FNLTG
SENCAYL---NSM--G------VS-----STACGK-N--LHSICSKAAK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------PPPKPPPKPP---PPP-P
K-----TPPPPKT-----PPPP-----------------------PPPPPPPPPH-IAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVVQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FSISG
TGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-M----------------------------------TSLEALK-----------------
--------------------------FLQ-TGHTC---RESM-SEGQ----SGE------
---DLQRKCLSIT-------SLP-----FPKLA--CFIIP-MAVLAAAVIALSTFLAV--
--------------------RGA------------DRQEY----------IRYVTCPKG-
WIGFGSKCFYFSED--A---KNWTVS---QMFCVS-LEAHLAQFETEE-EL--KFLKRYK
G-----PSDHWIGLSRESP--HHVWRWTDNT---EYN-----AS-----------FVIRG
VGECAYL---NDI--G------VS-----SARTY-TD--RNWICTFFLTSFCLTSLLHLQ
FDTKK---------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SNN---
---------------------------VE-KDIA----P------SELPANPGY------
---------------RHSKEHSS-----KATLIWPLFFL---ILFL-TIIVCGIVVAL--
-------------------SA---------INANCHQKSSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----R------------LVIKE
DGANLYV---AKVSQV------PRMNPTPVMVSYP-G--SRRVCLFE-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----A
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--E---KDWNSS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFRWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAL---NKN--S------LQ-----ASSCEV-P--LQWVCKKVRP-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MDSQRGA-KDANLSLRCIK--DKLLPIAG--------TVL-VAALLIAVI----
--------------------------------AL----AAAPH---------LPGCPND-
GIGVGLQCFYFVED--A---ADWDGG---QRFCLS-RGAQLAAVGTPQ-EL--GFVLRYG
R-----SVQYWIGLRRD---RSGPWMWANGS---LFN-----N---------A--YSIEG
SGRCAHT---DGG--G------IG-----SAECSR-P--KRSVCSRPQRGGAEL------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------LSEA---------------------
----------------------------------------KVE------------EASM-
CML---K-------------RD--LI------------TPDSLQEVK----IGK------
---KLQGKCLRNV-------SPE-----SPVKLYCCYVVI-MVLTVA-VIALVIALS---
-----------------VSKENT------------AISGSG---------PYYSTCPND-
WIGFGNKCFYFSED--V---RNWTFS---QTYCMA-LEAHLALYDSLE-EL--NFLKRYK
G-----ASDHWIGLHRESS--EHPWTWTDNT---EYN-----NL-----------VLTQG
SREYAYL---NDS--G------IS-----SAKNY-TP--KKWICSKYSKYT-LQCPEILN
PG------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MR-----------E-EL--
-SG--------------TENS-------------PLHL-----------ERGTQS----Q
NRNSMMTPESDGH----------LQCPIPCAVL---TVVFIVTLII-ALISLSVGQ----
YN----CPGIYTK---------------ENTYPLMTSMPLAPP---------VSSCPDS-
WIGYQGNCYIFSNT--T---GNWSTS---QYACSF-HDSTLAQIASME-DL--IFLQRYA
G-----SVEHWIGLRNE-T--NQEWRWTNDK---EFS-----GW-----------FNLTG
NGNCAYL---RNT--E------VS-----SANCQE-D--LHWICSKPTKH----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MKSF-----
---------------ASPERK---------NEGCPNL-LPAVF---------ADPCPKG-
WLGYQMKCYYFSVN--E---GNWTSG---NSHCSS-HNASLAVVGSQE-TL--DFFLRYK
S-----PPDHWIGLQKD-S--GQPWRWINGS---IFT-----EGF------FT--LPTEK
GRRCAYL---NHK--A------VA-----SSNCTR-E--EFWICSKDMFKSIA-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------LTD-------------DGIY
SEL----------------------------------QLSTEPQVQNDYRPQQTV----S
--------SSRF------------------R-LSRHVAIA-LGLL--NTIFVC--FLL--
VQ-------------WILCQD--------SKC-S----TCASC----------RSCPDL-
WMKYGNHCYYFSVE--K---RDWNSS---QKFCLG-EDSQLLMFTDDQ-EM--SLLKCFL
K-----KEFYWIGLRNN-----SGWRWEDGS---ALNISRILA--------------NSL
IQKCGTF---SEE--G------LR-----ASSCEV-L--LQWICKKWWPFADKAVF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------LI-TVTLFT-SVRWP-
PESN---------------LP---------HVSTSAPQIAKCP---------GACCPDG-
WVGYRGKCYYFSDA--E---GTWNSS---QSFCSS-FNASLAGIDTEK-DL--TFIMRYK
G-----ISEHWIGLKRV-S--DQSWQWVNSK---QFN-----NL-----------FPVRG
KGDCVYL---SDS--F------AT-----SSWCHT-Q--RYWICSKPDGMPREDVMPGG-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------C-P
AL--N-NPSL-TL--------------------------------QPPPPLRPRS-PAE-
------------------AEAR-----G----PEALLR------------RSGSG-Y--E
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCRT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

MEEA---WEAAPGGQAGAELP-MEPVGSLVPTLEQPQVPAK----VRQPEGPESSPSPA-
--------GAVEKAAGAGLEPSSKKKPSSPRPGSPRVPPLSLGYGVC-------PEPP--
------------SPGPALVKLPRNGEAPGA----------EPAPSAWAPMELQVDVRVKP
VGAAGGSSTPSPRPSTR-----FL--------------T--VPVPESPAFSRHADPAH--
---QLLLRAPSQGGTWGRRSPLAAARTESGCDAEGRASPAEGSAGSPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--DGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QQCPPG-
WVLSEEHCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGED-----NL
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------RE----A--------------------------------AEDS--------SL-
--------------------GS-----S----GCGRMV------------GSGEP-L--V
G-----LDSF-LS-----S------SDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ME--EMREY-PNFLGTERS----------RREGP------
----S-----HGACITFQLT----------MA----AVF--TVLLI-TAVAFAVQ-----
-----------------------------------AFQPHPQP---------CAQCPFD-
WVGFRGKCYYFSED--E---SNWTSS---QNNCSA-LGASLAVFDSTE-DL--SFTMRHK
G-----SSPHWVGLSRE--GEEHPWEWMSRS---PS------SH--------P--FQVQG
DGLCAYL---GDL--G------LT-----SSHCSA-H--RNWVCTKPALQNPRKN-----
-------FCIST--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VVL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFL
S-----EAFRWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-P--LQWVCKKIIF-ANQALF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DF--
-SA--------------TETS-------------SLHL-----------KREQQS----H
ATGTYSATYHEGS----------IQVPIPCAVV---NVVFITTLII-ALVALSVGQ----
YN----CPGQYA-----------------------SSAPPNTH---------VFPCSDD-
WIGHKGKYYLISKK--T---KNWTLA---QNFCSK-HGATLAVIDSKE-DM--NFLKQHV
G-----RAEHWIGLKNE-A--GQTWKWSNGQ---EFN-----NW-----------FNLTG
SENCAVL---NSA--E------IS-----STECDK-N--LHWICSKPSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SI--------------TENS-------------SSHL-----------EEGQKN----S
GASMHFEKYHEGS----------IQVPIPCAVL---TVVIITSLII-ALVALNVGH----
YN----CPGLYE-----------------------SSMSSDGR---------VASCSDE-
WVKYQKKCYFFSST--T---QSWTLA---QDSCSK-DGATLAVIDSSK-DL--MFLKRYA
G-----GAKHWIGLRNE-V--NETWKWPNGR---TFN-----NW-----------FNMTG
SEKCAFL---NLT--D------VS-----SADCEK-N--LHWICSKSSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MSA
AE----------------------------------PAETFVS-----------------
-------------------------------ILGT---TPRLQE-GE----MGK------
---KFQGKCLRFV-------CTE-----SPVKLYCCYAVI-MALTV-AVIVLSVALSL--
----------------PA-RSPE------------QTSMK----------NTYAYCPRN-
WIGFGSRCFYFSEN--T---NNWTTS---QTFCKE-QEAQLVHFDSWE-DL--NFLRRYK
G-----TSDYWIGLKRESS--EHPWMWTDNT---EYN-----NL-----------THIQG
VGDYAYL---NKN--G------IS-----SARVY-AD--RRWICSKPSNYTLQ-CQIPLS
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------E---NDWNSS---REHCNA-HGASLVTIGSAE-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKVHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------E-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------RRD-------------SAIY
STV----------------------------------ELPTVVEAQDDCRLQRKA----L
--------PSRS------------------C-FFCLVTIA-MGLL--NILLMS--LLL--
YH-------------QILCHG--------LHG-S----TRASC----------PSCPDF-
WVKYGNHCYYFSVE--K---KDWNSS---LEFCTA-SDAHLLRLMDNQ-EM--SHIQHLI
N-----KDYYWIGLRKN-----SSWRWEDGS---ALNFSRVSS--------------NSF
VQRCGVI---NVH--G------LQ-----SSSCEV-P--LQWICKKLRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------RSTFHEKPSECL----------AACPEN-
WIGFQRNCFHFSDD--T---KNWTFS---QRFCDL-QGADLVQVETLQ-EL--GFLLRYK
G-----PSDHWIGLSRE-Q--GQSWKWINGS---EWI-----RC-----------SPITG
GGECAYL---NDK--G------AS-----SARRYT-E--RKWICSKPDTYT---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-EC--
-SI--------------SENS-------------SLRP-----------KSGEQR----T
AASPHFVTPHEGS----------LQVPVPCAVV---TVVFITCLII-ALVALAVGQ----
YN----CPGQYM-----------------------TSVPSDSL---------ITSCSDE-
WVGYQRKCYFFSPR--K---MNWTLA---QSSCSK-YGATLALIDSEK-DM--IFLKQYV
G-----RTEHWIGLKNE-D--GQTWKWSNGK---VLN-----NW-----------LNLTR
SENCAFL---NST--G------VS-----SEECQN-T--LHWICSKPSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MEELIQ
S-----PSNHWIGLRRESS--HHIWKWMDNT---EYN-----NT-----------LAIRG
GRECAFL---NDN--G------V--------RIF-ID--RKRICSKPNSYVCS-CQLCPH
WDPT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------M-
---------TGSLVVSL----------ID-NSNQ----G------TDA-KKQDV------
---------------KDKSK--------M------TILV---RVLC-VIFFIL--N-I--
------------------------------LLIIVLVLEHRST---------QYSCPDD-
WIGFQNNCYYFSKE--E---RDWTSS---RHNCTT-QQADLTMIDTME-EM--NFLRRYK
C-----TSDHWIGLEMT-E--NKSGRWVNGT---IFK-----KW-----------FLVRG
NEKCAYL---DDD--G------AA-----TARCYA-E--RKWICRRKMH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------IGK------
---DLQRKCLAVL-------SPL-----TLAKVSCYLFII-AVSTA-GVVALSTVLS---
-----------------V-RQEK------------VVSEP----------TLYAVCPKS-
WIGFGSKCFYFSED--T---KNWTVS---QAFCAS-LEANLAQFETLE-EL--NFLKRFK
G-----PSDHWIGLSRESA--QDIWKWTDNT---EYT-----LS-----------FAIGE
DGERAYL---NDN--G------IS-----SARTY-TD--RKWICSKPNSYVNK-CQ-NR-
--------------------------------

MERV---WEAARGGQAGAELP-MEPVGSLVPGLEQPQVPEK----ARQPEGPESSPSPS-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPPLSLDYGAC-------PEPP--
------------SPGPASVKLPRNGEAPGA----------EPAPGAWAPMELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQADPAH--
---QLLPRASSLSGTWGRGSTLAAAGTESGRDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--EGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYFSVE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PRL-LPEDGKD-----NP
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MESAGSHCNCKTHKTVALRVAV-------VV-IFGLLIAVI----
----ALAVLS--------------------------GRSPAAW---------GPCCPDT-
WVGYQGKCYYFSKT--E---GNWPDS---RSNCSA-LGASLAAIDNKQ-EM--FFMQHSK
G-----KFDHWIGLWRH-P--DQLWKWANGT---KFN-------H-------W--FVIQG
GGDCAFL---NDEN-R------IS-----SSRCTS-E--AQWICSKPDEFF-WVIWNCGE
NPG-----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTE-------------SVIY
SMI----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-RSCLVAIA-LGLL--TAVLMS--VLL--
HQ-------------WIPYQG--------SNY-S----TFASC----------PSCPDL-
WMRYGNHCYYFSVE--K---KDWNSS---LQFCLA-RDSQLLIITSNE-DM--SLVQGFL
S-----EAFWWIGLRNN-----SGWRWEDGS---PLNFSRISF--------------NSL
VQTCGAI---NKD--L------LQ-----ASSCEV-L--LQWVVIFAD----QTLF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MV-------------TGGKMHD-----------S-----
-------------------------NNVE-KDIAPSEL----------PANPGY------
---------------RHSKE-HSSKATLIWPLFFLIMF----L----TIIVCG----MV-
---------------V----------ALSAINANCHQKSSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMLQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAPEPAREPPAPRDPS--
REPPARARPPPPA-----AR-------------------------PALSAPRPRS-PGE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MMLENVYRAS------------QTS-----
----HAPGHHRATF-D--GKKLLT----LWTLLCGGVVV-----LV-W----AF------
---------------FTLPRK-------FGNARVIRNKTCDDE---------VKICSST-
WLKINQNCFFLFQH--K---NAWLSA---QENCQH-YEANLAKFTTKM-EL--ETLMRHV
QS---LRSSFWIGLNRRNL--RRFWVWTDES---IYN-----NV-----------KEVQD
HGDCAFM---HKS--G------ID-----STNCDE-L--RDYICSKLGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------CLNG-
WIGYLGKCFYFSEN--T---RTWAAS---QNFCAP-HAATLAVFNTTK-EL--DFLKQYS
N-----HSQYWIGLSPC-S--PNPLPFIFLS---VFC-----FR-----------FKIIG
IGECAYL---HKI--G------IS-----SASSHL-V--RKWICSKPDP-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MLD-----------Q-----
----RPQDIQLPTMGDGVQQTS--ERN------------------------QET------
----------TE--NERGITFRCKVY--LAWIFAIPLVV------I-ALLSYCLV-----
--------------------------------------KAQNA---------PYFCPDN-
WIGFQDKCYYFSKE--E---KNWNSS---KDSCLS-ENADLVLISTPE-EM--QFLKRYK
C-----TSDHWIHPG------SQTKPWTERS---TLN-----H---------W--LTTKE
NEVCPYL---NED--G------IA-----TARCYT-E--RKWICKKKIR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MMNS----E------LRDGRSDGL------
---------ICR--TICKKKI------------CLGICF---PIFI-LC--ISA------
----------------------------------IVICSKLAK---------PVACSED-
WLGVRDKCFYFSDD--T---RNWTAS---KMFCSL-QKSELAQIDTQK-DM--EFLKRFA
G-----TGTYWIGLSRK-P--EDSWKWTNGT---TFS-----NW-----------FEITG
NGSYAFL---SAD--G------VH-----SSRGLI-D--IKWICSRHKF-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------L--ICPTL-SLSV---LQ----
--------------------------------HCELCSPRTGF---------SHVCPNA-
WLGFQGKCFYFSDN--E---SDWNSS---REQCQR-LGASLATVDTEE-ER--VFMLRYL
G-----PANCWIGLHRA-E-GDEHWTWANGS---TFT-----N---------W--FQLRG
GGRCAYL---NGD--R------IS-----SALCHT-E--KLWVCSRADSFVL--------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MPGA---------------------
----------------------------------------ADT------------KDST-
CMP---E-------------TV--SI------------ATDLFQEEE----TGK------
---KLQVQCLRIV-------SPE-----SPAKLYCCYAVI-AVLAAA-VIALSVALS---
--------------------ERP------------VNKTCG---------PCHTTCPRD-
WVGFGSKCFYFSED--L---RSWTFS---QTSCMA-QEAHLARFDSLE-EL--NFLKRHK
G-----DSDHWIDLYRESP--EHSWRWTNNT---EYN-----NL-----------VPIRG
EGECVYL---SDN--G------IS-----SGRGY-TY--RKWICSKPASGFKCRVGNVPK
HA------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MIP-----------E-DS--
-SM--------------TENS-------------SLHP-----------EKGQQX----X
XXXXXXXXXXXXX----------XXXXXXXXXX---XXXXXXXXXX-XXXXXXXGQ----
YN----CPGHST-----------------------ALVPSDSP---------ASPCSAG-
WIGSQKKCYHLSTK--R---SNWTMA---QGYCSE-HGATLALLDSEK-EM--IFLKQYM
S-----GLEHWIGMNNE-T--GQTWKWSNGR---ELN-----NR-----------SSEME
SGNCPFF---NTT--D------VS-----STACQR-R--LHWICSKPSHQ----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSC-----------G-DC--
-PI--------------TETS-------------SLRQ-----------EEGKKN----S
ATTPYFETEHEGC----------LRVPIPCAVL---MVVIITVLII-ALTALTVGK----
YN----CPNQYK-----------------------FSTASESH---------VSSCSDE-
WILYHRKCYFFSTT--T---QSWTSA---QNSCSE-DGATLAVIDSIK-DM--AFLKRYA
G-----RAEHWIGLKNE-T--GQTWKWSNGK---EFK-----HW-----------FNLTR
SGSCAFL---NST--E------VS-----STECEQ-S--LHWICSKPSRS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSL-----------E-DA--
-ST--------------TETN-------------SLHP-----------NRGQPS----N
ATGPHFATHHEGS----------LQVPIPCAVV---NVVFITVLII-ALIALSVGQ----
YN----CPGQYV-----------------------PSVPSNMH---------VSSCPDD-
WIGYQTKCYFISKK--T---KNWTLA---QSFCSKHHGATLALLESKE-DM--VFLKQHV
G-----RAEHWIGLKNE-D--GQTWKWSNGK---EFN-----NW-----------FKLTG
SKNCPFL---NST--E------VG-----SMECEK-N--LHWICSKSSI-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LEFCRA-RDSHLLRITDKQ-EM--SLLQDFL
S-----EAFHWVGLRNN-----SGWRWEDGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-P--LQWVCKKL-F-ANQALF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MEELIQ
S-----PSNHWIGLRRESS--HHIWRWMDNT---EYN-----NT-----------LAIRG
GGECAFL---NDN--G------V--------RIF-ID--RKWICSKPNSYVCS-CQLCPH
WDPT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFII---VGVL-I------------
-------------------TT---------NIITLIVKLTRDS---------QSLCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNIE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---TFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKRIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CVII---GVTL-II--------I--
-------------------TN---------IITVNIVKLTQDS---------QSLCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYSCST-QHADLTIIDNIE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---TFT-----KS-----------FGMRG
SEGCAYL---SED--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FV--------------AENS-------------SLHP-----------ESGQEN----D
ATSPHFSTRHEGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSED-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSEK-DM--NFLKRYA
G-----REEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNVTG
SEKCVFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------ASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQSCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FPVSG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MS----------------------------------ATECMLK-----------------
------------------------------TELTS---PDGLHE-AE----KGK------
---KLQRKCLTLA-------SPV-----TSTKLCLCCLLT-TVLTA-AVVGLSVALLV--
-----------------R-KPEQ------------AISNP----------IYYPSCPRN-
WIGFGNKCYYFSED--T---RNWTHS---ENFCMA-LQAVLAQFENLE-DL--NFLRRYK
G-----PSDHWIGLHRESS--GQPWKWTDNT---EYN-----NT-----------VSIRG
VGEHAYL---NDN--G------IS-----SARVY-AD--RKWICSKPNSYILQ-CQIPST
YF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SDIY
YTL----------------------------------ELPAAPQVPDGSRSKLKA----V
--------LQRP------------------R-LSCLLTVA-LGLL--TV--ILLSLVM--
YQ-------------RILYCG--------HKN-CTSCPSCPSC----------SSCPDL-
WVRNGSHCYYFSVE--K---KDWNSS---LEFCVD-RGSHLLTFLDDQ-EV--IPIRKHL
D-----KTFYWIGLRNK-----DGWRWEDGP---VLS-LRIFS--------------NSL
IQRCGTI---HRT--G------LQ-----ASSCEV-P--LQWICKKAVH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MESEGIENRDGMEV-----
----VEQKVKRPGV-V--TKKMLV----MSSMLCGGIAF-----LL-W----AM------
---------------LGFPRK-------FKNPRIFKDNTCSED---------ETICPQG-
WNQVNNNCFFQSEH--E---KTWIDG---QANCIA-YRGSLAIFNSKN-EV--ESLMPYL
E----P-SSYWIGLKKPNA--SAPWVWANGD---AFD-----NW-----------FNIEG
SGTCAFM---FKN--G------IS-----SASCND-A--IKYICSRESFCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGE-----------G-DQQ-
-E-------------------------------TFSEHK-------ADVSPPTL------
----C----PPGS-WCYGTGRRRSR--VQLIAVCAALGT--LILVL-VV--ISTVC----
--------------------------------RQVPVPPFPDF---------AHVCPNA-
W----GKCYYLSKE--E---NDWNSS---REHCNA-HGASLATIGSED-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQNAHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-DC--
-PI--------------TETS-------------SLHQ-----------EKGGKN----S
ATHLHFETQHEGS----------LQVPIPCAVL---IVVFIIILVM-ALITLSVGK----
YN----CPSQYE-----------------------FSMPSESY---------VSSCSDE-
WVLYHRKCYFFSST--T---KSWTSA---KDSCSE-DGATLAVIDSKK-EM--VFLKRYA
G-----KAEHWIGLKNE-T--GQTWKWSTGK---EFN-----HG-----------FNLTR
SESCAFL---DST--E------VS-----SAECEQ-H--LHWICSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------IRR--TICNFKPNW--------KICFCVCF---VI---ISAACII------
---------------------------------MIVKWPKCDK---------RVACSGD-
WLAVREKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKRYA
G-----TDMHWIGLRRK-Q--GDSWKWTNGT---TFN-----HW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYPL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------IIAVYVVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------A------
---------------MGRHK--------K------TIAT---IALF-IIIVIT--V-I--
-----------------------------------VTINVLYP---------RSFCPDD-
WIGFQDKCYYFSEK--E---GDWESS---RGNCSK-EHADLTTIDSEK-EM--SFLRRFK
C-----TSDHWIGLKMK-E--NRTGRWVNGT---IFT-----EG-----------GKVKG
KEECAYL---DAD--Y------IS-----TARCYT-D--RKWICRKTMY-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MERSD-------------SAIY
STI----------------------------------ELPSAAQARDDCRPQQKA----F
--------SCRS------------------S-LFCFVAIA-LGSL--NILLTS--LLL--
SQ-------------WILCQG--------PCD-S----TCASC----------PSCPDF-
WMRYGNHCYYFSVE--K---KDWNSS---LEFCTA-SDAHLLRLTDNQ-EM--SLLQNLI
D-----QDFYWIGLRKN-----SSWRWEDGS---ALNFSRVSS--------------NSL
IQRCGAI---STY--G------LQ-----SSSCEV-P--LQWICKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MV-------------TGSKMHD-----------S-----
-------------------------NNVE-KDIAPSEL----------PANPGY------
---------------RHSKQ-HSGKATLIWPLFFLIMF----L----TIIVCG----MV-
---------------V----------ALSAIRANCHQKPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDAALAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGEYAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMVQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFII---FGVL-I------------
-------------------TT---------NIITLIVKLTRDS---------QSLCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNIE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---TFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKRIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MAD-------------STIY
CTL----------------------------------EFPATSQGREDCRPQPKA----V
----F---SRRR------------------S-LPCLMAVA-LGLV--TVILLS--ILV--
YQ-------------QILCYG--------SKD-S----TCDRC----------LSCPNL-
WLRNGSNCYYFSVK--K---KNWNSS---LEFCTD-KDSDLLMLKDSQ-EM--YLFQDSL
N-----QEFHWIGLRNN-----SGWKWEDGS---VLN-SRINS--------------NSL
VQKCGAI---NKS--G------LQ-----ASSCEV-P--LQWICKKVIS-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
AV----GMGHNQS-----L--SLS-SDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHS-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FPIAG
PGECVFV---EPT--R------LV-----STDCLM-T--RPWVCSKMAYT----------
--------------------------------

--------------------T-EQPL-----------VVVE----ARPPEVPDGHPRAER
--------AGREAADAELRELLQEKPQPPAASGTPRLPPLSLGYGAFRRLGSCSRELP--
------------PPSPTRAEQPRDGEAE---LQPWAASG-EPAPGSWAPMELQVDVRVKP
VGAAAASRSPSPAPSTR-----FL--------------T--VPVPESPAFARR--PAL--
---PRLPHAPSPGSTWGRGSPLAATPTL-----TERIGAAEGSAVSPDSPTCRCRCRCQ-
-------GPGLSEEDAGLLQS-----AG--VDSKSLPRAVTLIG-LPLY-----------
---------MKSL-------RWALVIMAVF--------L--AVCTV-----TIVAL----
--------------------------------ASRGGARC-------------QSCPQG-
WLWSQEHCYYLSEE--A---QDWEGS---RAFCSA-HQATLPLLNHTQ-----GFLRKYQ
I-----SKDSWVGAQRG----PEGWHWTDGV---PLP-----SQL-LPEDSED-----HP
DFGCGGLE---EG--R------FV-----ARDCSS-L--RPWVCARRAR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MVN---------------NED--NHETE-KGFIPN-------------GDGQP------
----TPEEGIKGLRWRFQHK----------LL----YAF--IVLLI-III-VVLG-----
-----------------------------------ILYGNSRH---------PTSCPTD-
WIRYNNKCHYFSNE--E---RNWTSS---ESFCNQ-FGASLATIDTEF--Q--ELMAHFK
L-----KTINWIGLRRD-PGQPQVWKWTNGE---ISS-----I---------E--VIGSD
GGDCTYL---NDEF-K------PS-----TSVCNQ-E--HRWICSKPTEVVRYIR-----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEGEE--------------
----MENRRKRRVQ-A--RRKMII----LSVLLCGGLAV-----LL-W----VM------
---------------LKFPKK-------AGIKR--TSNNCTDE---------MRVCLPD-
WDLISETCFFQSEH--E---AIWAEG---QKHCRK-YYASLAKIVSRT-EM--ESVVSYL
N----T-STYWIGLRKHPS--DNIWRWMDGS---HFN-----NW-----------FTITG
SGNCAFI---SDR--G------MG-----ISSCNE-T--RRFLCSRRSQCV---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGK-----------G-NQE-
-KN--------------HP-----------------DQE-------EVMNLPRD------
----EEKQCKWGF-SPHGMKKKCRRVKKLLTPLCVVLTV--LVLAL-VVALVVVLL----
--------------------------------Q--SHSSHPQF---------SDVCPDK-
WIGFQSKCYYFSED--E---SNWKTS---LENCKA-MEASLTSIDSQE-ELIKAFIKRFK
G-----QANHWFGLHDE---DNSQWRWTNGA---AFN-----N---------W--FEVRG
GGPCAYI---NQ---E------IS-----SAFCNT-E--KYWICSRPNNYVLWRQKIYP-
--------------------------------

------------MERAGPELP-MEPLRPVGSE---------------------SAPA-R-
---------------------------APPGATGAPELPRSLGLG------SDGSPGP--
------------SPTP-AAEEPRDGESPG------------PEPGTRAPMELQVDVRVTP
VGAASG-RTPSPAPATR-----FL--------------T--VPVPESPACQARAPPL---
---------PSPGATRNPSPPS-----------------GPRNASRPGVPPGCCRCRCR-
-------EPGLKADGAALLPD----------A------GDKLPR-LPTY-----------
---------MRSL-------RWALVIMAFL--------L--AVCTI-----TMVAL----
--------------------------------ASRAGARC-------------RRCPQG-
WMWAEGQCFYLSTD--T---GTWEAS---QAFCSA-HHATLPLLSHTQ-----GFLSKYH
V-----VPRSWVGALRG----PRGWYWTDGT---PLP-----LQL-IPEEEEQ--HENPS
ELSCGGLE---EG--R------LA-----ALDCTA-P--RPWVCACEPQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MTAA---------------------
----------------------------------------KIK------------EAST-
GLL---K-------------TD--VT------------TPDSLKDVE----IGK------
---KVQGKCLRII-------SAE-----SPAKLYCCYGVI-AVLTVT-VLSLSVALSL--
----------------S---GRP------------VTENSG---------PCYATCPKD-
WIGFGNKCYYFSEE--M---RNWTFS---QTSCMA-LEAHLAIHESQE-EL--NFLKRYK
G-----PSDHWIGLHRESP--EDPWMWTDNT---EYN-----NL-----------VLTQG
GGEYAYL---NDS--G------IS-----SAKDY-IH--KKWICRKSKICT-SQCPEILN
PG------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLLS--VLL--
YQ-------------WILCQG--------SNY-S----TCASC----------PSCPDR-
WMKYGNHCYYFSVE--E---KDWNSS---LEFCLA-RDSHLLVITDNQ-EM--SLLQVFL
S-----EAFRWIGLRNN-----SGWRWEDGS---PLNFARISS--------------NSF
VQTCGAI---NKN--G------LQ-----ASSCEV-P--LHWVCKKCPF-ADQALF----
--------------------------------

-----LERGASKEDGAGAEFE-MDSLGNQVPEMEQPQHPAE----ERRPESPENSLS-LA
--------P-AKEAAGAGQDLSGGKMLPSPRPAPLRLLPPSLGYGAFRRQASTGPEPP--
------------SPDPAAAEQPRDGETPETELIPKAAPG-EPAPGAWTPVELQVDVRVKS
VGTAGGSRAPSPAPSTR-----FL--------------T--VPVPESPGFSRHASPAH--
---TLLRRTPSPGGTWGRGTPPAAAGTERGLDVEGCASPAEGRAESSGSPMCRCRCR---
--------------EDSVLLPH---AEL--DGDKKMSRIIKRVG-LPMY-----------
---------MRSL-------RWALAVMAVL--------L--AVLAV-----AVVAL----
--------------------------------ASKTGIRC-------------RPCPQG-
WMWSEGQCYYLAAE--A---EAWETS---QAFCSA-HQATLPLLRHTQ-----DFLSRHP
V-----TRYSWVGARRG----PQGWHWIDGT---PLP-----PQL-LPEEDQD-----QP
DLECGCLE---GG--K------LV-----ASDCAS-P--RPWVCAKGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SNN---
---------------------------VE-KDIT----P------SELPANPGC------
---------------LHSKEHSI-----KATLIWRLFFL---IMFL-TIIVCGMVAAL--
-------------------SA---------IRANCHQEPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------LVMKE
DGANLYV---AKVSQV------PRMNPRPVMGLTL-L--PRLECSSTIVAHCSLDFPGSS
EPP-----ISAS--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MAACK----------NPLETET-----------K-NGN-
-SLNTSEQIALDFSGKTKASER--EQLTQ--TSIPLPAD---------RSPST-------
---------------HILARGPKTKWKKKKNCILMTVL-----------PIASSVV----
------------------------------------TALIATT---------VLSCPSG-
WVGYEGKCYNFSES--E---GTWDSS---QNNCSA-SGASLVVIEDQK-EM--DFIMQHK
R-----ATDYWIGLKRE-K--GQPWKWPNGT---VFN-----G---------W--FEIGA
DGPCAYL---NDE--K------AS-----STLCVT-R--RNWICSMPAHGV---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ME-EL--NFLKRYK
G-----PSDHWIGLRRESS--HHIWKWTDNM---EYN-----NM-----------LAIRG
GGECAFL---NDN--G------VN-----SGRIY-MN--RKWICSKPNNYVYS-CQLCPH
WDTT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MAD-------------SDIY
CTL----------------------------------ELPATPQVQEDSRSKLRA----L
--------FRRL------------------P-LSCLVTVA-LGLL--TV--ILVGLLM--
CQ-------------RIPCCG--------SKD-S----VCAHC----------PSCPNL-
WMRNGSHCYYFSTE--K---KDWNSS---LEFCAD-KGSHLLMFLDDE-EV--IPFQKYL
D-----NDFYWIGLRKT-----DGWRWEGGP---ILS-LRIVS--------------NSL
IQTCGTI---HKD--G------LQ-----ASSCEV-P--LRWICQKTTN-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------XPAAPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------K-----------------
------------------------------QKFS----KSTLSYYSF----TGK------
---NCQGKYLRII-------SAE-----SPVKLYCCYGVI-AVLSG-AVIALSVALLL--
----------------SRAGKPE------------EVSNK----------NIYYDCPRD-
WIGVGSKRFYFSEK--V---ENWTSS---QTFCVA-QGAQLARFDSPE-EL--EFLKRYK
G-----EHDHWIGLHRKSS--EHHWMWTDGT---EYN-----NL-----------TSPRG
GGECAYL---SDS--K------VS-----SGRNY-TH--RRWICSKPNSFTA--CDVPKQ
S-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------L--TCPTL-SLSV----L----
--------------------------------QSPSCSPRPGF---------SHVCPNA-
WLGFQGKCFYFSDT--K---SDWNSS---REQCQH-LGASLATVDTEE-ER--AFMLQYR
G-----PANCWIGLHRA-E-GDEHWTWADGS---AFT-----N---------W--FRLRG
GGRCAYL---NGG--R------IS-----SALCHT-E--KLWVCSRADSFVLWRNGTNPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINS----E------LRDGRSDGL------
---------IRR--T---------------------------------------------
-----------------------------------IICSKRAK---------PVACSEG-
WLGIRDKCFYFSDD--T---RNWTAS---KMFCSL-QKSELAQIDTQK-DM--EFLKRFA
G-----MAMYWIGLSRK-P--EDYWKWTNGT---TFN-----NW-----------FEITG
NGSYAFL---TAD--G------VH-----SSRGFI-D--IKWICSKCK------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------CSSGPPA---------GPGCLDD-
WVGYRGKCYYFSEV--E---GNWTNS---QTNCSG-FRASLVVFDSEQ-EK--V-RERDG
H-----RLNHWLGLRRE-Q--GQPWKRVNGT---EFN-------L-------W--FDIKG
GGDCAYL---SPA--F------VG-----SSRCSS-H--AHWICSKQDAYT-AGKNVTIP
V-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MSAA---------------------
----------------------------------------KVE------------EASI-
GML---K-------------TD--LT------------APDCLQEGE----MGK------
---KLQAKCLRII-------SAA-----SCVKLYCCYGVI-MVLTVA-VAALSVALS---
-----------------VRKKKP------------VMESCE---------PCYAVCPSG-
WIGFGNKCFYFSED--M---GNWTFS---QSSCMA-LDAHLALFDSLE-EL--NFLKRYK
G-----ASDHWIGLHRESS--EHPWIWTNNT---EYN-----NL-----------VLTRG
GGEYAYL---SNG--G------IY-----NSSGD-IH--KKWICNKPNSYT-LQRPLIVN
PG------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------M----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MANT------------ALQQGQ-----------E-KRH-
-NL--------------DPEEQ--KSAGE--KLI--WPE------THGIRVPFR------
---S--EE-SIGL-HHDREVPGCACGKASCLKAFAGIAG--AAVVT-TLIILTVLA----
----SRSYVT--------------------GSPSPATWYPASC---------GPSCPDG-
WVGYRRKCYFFSET--E---GNWTDS---RKQCSA-LNASLALIESEQ-EL--IFMLRFK
V-----RTDPWIGLQKE-P--GQGWKWANGL---EFN-------N-------L--FVIRG
EADCAFL---SED--T------VS-----SSRCYT-E--RNWICSAPEAHA-KGADTSGE
GTREAP---------G----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MVEP----E------LRDGRSDGL------
---------MRQ--TICKMKI------------CLGICV---LIII-VP--IFT------
---------------------------------IIGIRSNCAK---------PVACSED-
WFGVRDKCFYFSND--T---RNWTAS---KMFCSL-QKSELAQIDTQK-DM--EFLKRFA
G-----TDMHWIGLSRK-P--EDSWKWTNGT---TFN-----NW-----------FEITG
NGFYAFL---NVD--G------VY-----SSRGLI-D--IKWICSKRK------------
--------------------------------

--------------------------------MEPPQVPAE----APQPRASEDSPRPER
--------TGREEPDAQPQELP-EKSPSPALSGSPRVPPLSLGYGAFRRLGSCSRELP--
------------SPSPSWTEQPRDGEAE---LEPWTASG-EPAPASWAPVELQVDVRVKP
VGAPGASRAPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPTL--
---QWLPRAPSPGSTWSRGSPLAANA-------TESVSPAEGCTVPPGSPACRC--RCR-
-------EPGLTKEDDALLQR-----AG--IDGRKLPRAITLIG-LPQY-----------
---------MKSL-------RWALVVMAVL--------L--AVCTV-----AIVAL----
--------------------------------ASRGGTKC-------------QPCPQG-
WMWSQEQCYYLSEE--A---QDWEGS---QAFCSA-HHATLPLLSHTQ-----DFLRKYR
I-----TKGSWVGARRG----PEGWHWTDGV---PLP-----SQL-FPADSED-----HP
DFSCGGLE---EG--R------LV-----ALDCSS-P--RPWVCARETK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------RWALAVMAVL--------L--AVSMV-----AIVAL----
--------------------------------ASKTGAVC-------------RPCPHG-
WLWSGEHCYYLSTE--A---QAWEAS---QAFCSA-HHATLPLLSHTQ-PM-EDFLGRYP
V-----TKYSWVGARRG----PQGWHWIDGG---PLP-----PQL-VPEEDKD-----QP
GLKCAGLE---GG--K------LM-----ALDCAS-S--RPWVCAQGT------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FI--------------TENS-------------SLHP-----------ESGQEN----D
ASSPRFSTQREGF----------FQVPVLCAVV---NVVFITILII-TLIALSVGK----
YN----CPGQYT-----------------------FSVSPDSN---------GFSCPDD-
WVGYQRKCYFISTV--K---KSWTSA---QNACSE-HGATLAVIDSEK-DM--NFLKRYA
G-----RGEHWVGLKKE-P--GQTWKWSNGK---EFN-----NW-----------FNFTG
SEKCVFL---KST--E------VS-----SMECEK-N--LHWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-NC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSLPSDSH---------VSSCSDD-
WVGYQRKCYFISAV--K---RSWTSA---QNACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---DFN-----NW-----------FNFTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------ML---------RKKKKAYYNDNVP---------KGCCPDK-
WIGFQRKCYYFSEK--E---ANWTSS---RDNCAT-EDAFLTKIDTQQ-EM--NFLRRYK
G-----NSDHWIGLTMI-N--NQTGNWVDGT---KF--------------------KVRG
REECAYL---NDD--G------AA-----TARCYP-E--RKWICRK--------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-NC--
-SI--------------TENS-------------SSHL-----------ERGQKD----H
GTSIHFEKHHEGS----------IQVSIPWAVL---IVVLITSLII-ALIALNVGK----
YN----CPGLYE-----------------------KLESSDHH---------VATCKNE-
WISYKRTCYFFSTT--T---KSWALA---QRSCSE-DAATLAVIDSEK-DM--TFLKRYS
G-----ELEHWIGLKNE-A--NQTWKWANGK---EFN-----SW-----------FNLTG
SGRCVSV---NHK--N------VT-----AVDCEA-N--FHWVCSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MSAA---------------------
----------------------------------------KVE------------EASM-
GML---K-------------TD--LT------------APDCLQEGE----MGK------
---KLQAKCLGII-------SAA-----SCVKLYCCYGVI-MVLTVA-VVALSVTLS---
-----------------VRKKKP------------VMESCE---------PCYAVCSSG-
WIGFGNKCFYFSED--M---GNWTFS---QSSCIA-LDAHLALFDSLE-EL--NFLKRYK
G-----ASDHWIGLHRESS--EHPWIWTDNT---EYN-----NL-----------VLTRG
GGECAYL---SNR--G------IY-----NSSGD-IH--KKWICNKPNNYT-LQRPLIVN
PG------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------IRR--TICNFKPNW--------KICFCVCF---VI---ISAACII------
---------------------------------MIVKWPKCDK---------RVACSGD-
WLAVREKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKRYA
G-----TDMHWIGLRRK-Q--GDSWKWTNGT---TFN-----HW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYPL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------DTIY
SIL----------------------------------EFSTASRDQSDFRGQQKV----L
---AA---SSRR------------------S-LSCHVAIG-LGLL--TVILMS--LLL--
YQ-------------WILFQG--------CSY-S----ACTNC----------SSCPDL-
WMGYGNHCYYLSVE--K---KTWNSS---MEFCLS-KDSQLLMLRDDQ-EM--NLHKKFL
S-----NDFYWVGLRNN-----SGWKWEDGS---ALK-SR--------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------IFTVCVVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTS-----------E-DY--
-TV--------------TESS-------------SVHL-----------ERGQKR----H
DSGFQFETHHEGS----------LRVPIPCAVL---TVFLITTLII-ALVALLVGQ----
YN----CPDQPK-----------------------FSMSSDVH---------ASSCSDD-
WVAHRRKCYLFSTT--T---NSWTLA---QNSCSK-HGATLAVIDSEK-DM--IFLKRYA
G-----RSDHWIGLQNA-A--GRMWKWSNGK---EYH-----TW-----------LNWTE
SEKCAFL---NNT--D------VN-----SAQCEK-K--LHWICSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPARAR----PP-P
PVA-A-RPAPTPA--------------------------------PAPAAPRPRS-PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MFQR
NP----------------------------------TSGENVE-----------------
--------------------------EGR-SGKLL---QILY-LLSQ----SGR------
---ILQRIRLAII-------SFV-----TSAKFYRFIFIA---SLAANLMLFYPLFPV--
--------------------KRR------------ELDSH----------VLHVPCLKG-
WIGFGSKCFYFSED--T---RNWTFS---QTFCTS-LEAVLAQFETKD-EL--NFLIRYK
G-----PFDHWIGLHRESS--HHVWKWTDNS---KYN-----AS-----------FAITG
DATCGYL---NDL--G------VS-----SARSY-TD--RKWICSKQIMSPCP-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MMNS-----------E-DG--
-CI--------------TENS-------------SLHP-----------EKGQQN----Q
AASPHFATQHEGS----------LQVPIPCAVV---NVVLITVLII-ALIALSVGQ----
YN----CPDPDI-----------------------SLVPSNSR---------VSSCSDD-
WIGYQRKCYFISTE--T---KNWTLA---QKFCYK-QGATLAFIDSEK-DM--IFLKRYV
G-----RVKHWIALKNE-D--GQTWKWSNGR---EFS-----NW-----------LNLTG
FENCTFM---NST--E------VS-----STACEN-N--LHWICSKSSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------V------
---------------MSRHK--------K------CFIM---GAIL-II--------I--
-------------------SN---------AITVLIVKLTPDS---------ERFCPYD-
WIGFQNKCYYFSKE--E---GDWNSS---KYKCST-QHADLTKIDSKE-EM--DFLRRYK
C-----SSDHWIGLKMA-K--NQTGQWVDGA---KFK-----KS-----------FVMKG
SEGCAYL---SDD--G------TA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------S
--------SARP------------------S-LSFLVAIA-LGFL--AAVLAS--LLL--
YQ-------------WIWGQG--------SSR-A----LRIGC----------PGCPDY-
WMRYGNHCYYFSEK--K---KDWNSS---MRFCLA-EGSHLIVLADNQ-EM--RLLTGFL
C-----EDFHWVGLRKD-----HGWRWEDGS---VLNSSRIHS--------------NSM
VQACGSV---NIH--G------FQ-----ASSCEV-P--LRWICKLSFD-N--TLLQ---
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------A------LTSPSLTGW------
---------------LSALKARIRPL----SLGFNFI-C---IIVI-TILIVL--ITR--
PA-K---------------TY------------ELCPAGAPCL---------LAACPFD-
WIGYQGKCYYFSEL--E---ANWTES---QKNCSA-LGASLAGIDLQW-EM--DFLRLHR
G-----SLDYWIGLDRE-R--GQTWKWANGT---DFN-----NW-----------FPIAG
EEQCAYL---SGS--V------VA-----SSSCGN-I--QRWICSKPAHKLEGEMK----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MRR--ADNIE-KDFVPTELI----------KNSGY------
----CPSKRHSGELTNYMW----FIL---C------LTF--MVCVL-V-TFFVTR-AI--
F----------------------------------HQNPSECL---------VPACPEY-
WIGFQRKCFYFSDD--T---KNWTFS---QRFCNS-QGADLVQVETLQ-EL--GFLLRDK
G-----PYDHWIGLSRE-E--GQLWKWINGT---EWN-----SL--------L--VIKEA
SLYVARA---LQAL-T------NP-----KSIM---------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SV--------------TENS-------------SSHL-----------ERGQKD----H
GTSIRFEKHHEGS----------IQVPIPCAVL---TVFFITSLII-ALVALNVGQ----
YN----CPGLYK-----------------------NPASSDRH---------VASCEDE-
WVAYQRKCYFFSTT--T---NSWALA---QNSCSK-DGATVAVIDSEK-DL--VFLKRHA
G-----GQEHWIGLNKE-A--NQTWKWANGK---EFN-----NW-----------FNLTG
SERCVSL---NNT--A------IA-----TVDCEA-N--LHWVCSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPSR----------
------ARPP-PP-----LAARPA---------------------PAPAAPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

--------------------------------MEPPQVPAE----APQPRASEDSPRPER
--------TRREAADAQSQELR-EKSQPPTGSGSPRVPPLSLGYGAFRRLGSCSRELP--
------------SPSHSCTEQPRNGEGE---LEPWTASG-EPAPGSWAPVELQVDVRVKP
VGAAGASRAPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPTP--
---QWLPRAPSPGSTWSRGSPLAATP-------TEPIGPAEGCTVPPGSPPCRCRCPCR-
-------EPGLTKEDDALLQR-----VG--LDGKKLPRAITLIG-LPQY-----------
---------MKSL-------RWALVVMAVL--------L--AVCTV-----AIVAL----
--------------------------------ASRGGAKC-------------QPCPQG-
WMWSQEHCYYLSEE--V---QDWESS---QAFCSA-HQATLPLLNHTQ-----DFLRKYQ
V-----TKGSWVGARRG----PEGWHWTDGV---PLP-----SQL-FLEDSED-----HP
DFSCGGLE---EG--R------LV-----ALDCSS-P--RPWVCAKGTK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SNN---
---------------------------VE-KDIA----P------SELPANPGY------
---------------LHSKEHSI-----KATLIWPLFFL---IMFL-TIIVCGMVAAL--
-------------------SA---------IRANCHQKPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------LVIKE
DGANLYV---ANVSQV------PRMNPKPVMVSYP-G--SRRVCLFE-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SNN---
---------------------------VE-KDIT----P------SELPANPGC------
---------------LHSKEHSI-----KATLIWRLFFL---IMFL-TIIVCGMVAAL--
-------------------SA---------IRANCHQEPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDAALAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------LVMKE
DGANLYV---AKVSQV------PRMNPRPVMGLTL-L--PRLECSSTIVAHCSLDFPGSG
EPP-----ISAS--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------AR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FAISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MI-T--P----E------LRESRHGNR------
---------ICR--QIHKLKKGW--------MLHLCMYL---SL---ILA-IAI------
---------------------------------VATKHSKCSR---------TMACEDE-
WIGLRKKCFYFSSD--T---KNWTAS---KRFCSS-QGSELAHIDTRE-DM--DFLRKHA
G-----TSMHWIGLNRK-Q--GESWKWTNGT---IFN-----TW-----------FEISG
NGSFAFL---NAD--G------VR-----SSRGFI-D--IKWICSKPKF-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MQTR-----------E-EL--
-SG--------------QENS-------------PLHT-----------ERGIQN----Q
TTN----SNPDGS----------LRVPVPCAVL---PVVIIAILII-TIIALSVGQ----
YN----CPGKYVS---------------ENTSPLMTSMSLDLS---------VSSCPDS-
WIGYRGKCYIFSNT--T---ANWT-P---QNACSS-HDSTLAQIDSKE-DL--IFLKRYA
S-----NVEHWIGLKNE-T--DQAWRWTNGK---EFS-----G-----------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MV-------------TGSKMHD-----------S-----
-------------------------NNVE-KDIAPSEL----------PANPGY------
---------------RHSKQ-HSGKATLIWPLFFLIMF----L----TIIVCG----MV-
---------------V----------ALSAIRANCHQKPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDAALAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGEYAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMVQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLMS--VLL--
YQ-------------WILCQG--------SKY-S----TCASC----------PSCPDH-
WMKYGNHCYYFSVE--K---KDWISS---LEFCLA-RDSHLLMITDKQ-EM--SLLQDFV
S-----EAFHWVGLRNN-----SGWRWENGS---PLNFSRIYS--------------NSL
VQTCGAI---NKN--S------LQ-----ASSCEV-P--LQWVCKKV-R-T---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------M------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------TIAVCIVKLIQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYDCST-QHADLAIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKVA-K--NRTGQWVNGA---VFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-EG--
-SV--------------TENS-------------SSHL-----------ERGERD----H
GTHMYFEKHHEGS----------IQVPIPCAVL---VVVIITSLSI-ALVALLVGQ----
YN----CPGLYT-----------------------NLASSDHP---------VASCEDE-
WLAYRRKCYFFSTT--T---NSWASA---QNSCSQ-EGATLAVIDSRK-DM--IFLKRHA
G-----EQEHWIGLKNE-A--NQTWKWANGQ---DFN-----HW-----------FNITG
SERCASL---NNT--D------IT-----TVDCEA-S--LHWVCSKPFR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MQPD------------PLPDSK-----------E-----
-------------------TQR--EQNGE--THVVSIPA------QSGRRRPTG------
---------V----------AGLLAGTQICDPVLCGSLC--VLVLF-SLTLIIIFT----
-------------VTAQSRKT---------SEPCPA--GAACS---------GAICPNS-
WVGYQGKCYYFSKG--E---GNWTDS---QSNCSA-LNASLVGIDSTQ-EL--EFMKRNR
E-----SYDHWIGLWKS-P--GQSWEWSNGT---KFN-----SSD-------R--LFIRG
GGDCAYV---DSE--G------IA-----SSSCSG-Q--LRWVCCR--------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MN-D-----------S-----
-------------------------NNVE-KDIAPSKL----------LANPDY------
---------------LHSKE-HCSKATLNWCLFFLIVF----L----TIILCG----MT-
---------------I----------TLRAIRTNCHQEPPVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDANLALVENFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--DQPWKWTNGT---EWT-----RL-----------FPIMG
GGECAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMI------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------X-----XXXXXXXX-XXXXXX------------RPRSP-------AE-
------------------VEGR-----G----PEGLLR------------RSGSG-Y--E
G-----ST----------------------------------------SW----KA----
--------------------------------ALEASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FPISG
LGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKTAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SAIY
SML----------------------------------ELPTTAQAENDYRSQQKA-----
--------SSRP------------------S-LACLVTIA-LGLL--NAILMS--LLL--
YQ-------------WIHCQG--------SNC-D----TYASC----------PSCPDL-
WMRHGNHCYYFSTK--K---MDWNSS---LHFCLA-EDSDLLMITDNQ-EM--SLLKDFI
D-----ENFHWIGLRNN-----SGWRWEDGS---ALNLSRIIS--------------NSW
IQTCGAI---NED--G------LQ-----ASSCEV-P--LQYICKKVRR-----------
--------------------------------

MERA---KEAAPESQAGAELP-MEPMGSLLPGLEQPQVPAE----TRQPEGPESSPTPA-
--------RTVEEAAAADPEPSSEKQLPLPRPRPLRLPPLSRGYG-----------PP--
------------SPGPSSAEPPRNSEAPGA----------EPAPGAWAPIELQVDVLVKP
VGAAGSSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRSAALAH--
---QLLQRAPSPGGTWSRGSPLAAARTESGCDAEGRASPAEGSAGSPSSATC---CRCK-
-------ELGLEKEGAALLPC----AGL--DRDKKLPRAVTHLG-LSVY-----------
---------MKSL-------RWALAVMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGTRC-------------QPCPPG-
WVLSEEHCYYLSVE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DLLSRYP
V-----SKHSWVGVRRG----PQGWHWIDGV---PLP-----SQL-LPEDGEN-----NL
DINCGALE---EG--T------LV-----AANCSA-P--RPWVCAKWTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------AE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------D-T--FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

MDGT---RKASEDGRAEAEFPQVELLESHDSDPEQPQGPGE----RRQPGSPQSSL----
-----------SEAAGGGQEPSDEKKPPPPRSGPLAMPPHSLGYGA-------SREPP--
------------SPGAAWAEQPRDGEAP---------GA-ELASGSWAPMELQVDVRVKP
MGAAVGSQAPPPSPSSR-----FL--------------T--VPVPESPASLAHP------
-----------LSSTEGQDSPLAVGP-------TERGSDAKGRAGSPGSPTCRCRCKEH-
-------E---VDEEAVQLLR-----AG--WDTKKLPRAMTLIG-LPTY-----------
---------MKSL-------RWALAVMAVL--------L--AVSTV-----VIVIL----
--------------------------------ASKTGGRC-------------QPCPRG-
WIWSEEHCYYLSAE--A---RTWEAS---QAFCSA-HHATLPLLSHTQ-----DFLSRYP
I-----TKQSWLGARRG----PQGWYWTDGV---PLP-----PQL-LPEE--D-----DP
AVSCGSLE---EG--R------LV-----AVNCSS-P--RPWVCTRHAQ-----------
--------------------------------

--------------------------------MEPPQVPAE----VPQPRASEDSPRLEQ
--------TGREVADAQPPEFP-EKFPSPALSGSPRVPPLSLGYGAFRRLGSCSRELP--
------------SPSPSWAEQPRDGEAE---LEPWTASG-ETAPASWAPVELQVDVRVKP
VGTAGASRAPSPAPSTR-----FL--------------T--VPVPESPAFARRSAPTL--
---QWLPRAPSPGSTWSRGSPLAANA-------ADPIGSAEGCTVPPGSPACRCRCRCR-
-------EPGLTKEDDALLQR-----AG--IDGKKLPRAITLIG-LPQY-----------
---------MKSL-------RWALVVMAVL--------L--AVCTV-----AIVAL----
--------------------------------ASRGGAKC-------------QPCPQG-
WMWSQEHCYYLSEE--A---QDWEGS---QAFCSA-HHATLPLLSHTQ-----DFLRKYQ
V-----TKGSWVGARRG----PEGWHWTDGV---PLP-----SQL-FPVDSED-----HP
DFSCGGLE---EG--R------LV-----ALDCSS-P--RPWVCARETK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------ICIFAVLVLV------VV-ALA----------
-------------VTVSLRGT---------HQPCPVC----HY---------SAPCEED-
WIWYRGKCYYFAET--Y---DEWNNS---QSFCVS-HNASLSLIDTQE-EL--DFLRRHK
G-----LYDHWIGLYRD-T-DEPGWVWANGS---MFR-------N-------T--FPIVG
DSPCVYL---NNG--H------VG-----SAACHG-D--RKWICNKMDANSHMTH-----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-DC--
-PV--------------TESS-------------SLHQ-----------EKGKKN----N
AASLHFETQHEGS----------LQVPIPCAVL---IVVFITMLII-ALIALSVGK----
YN----CPGQNE-----------------------FSLPSASH---------VSPCPDA-
WVLYHRKCYFFSTT--T---KSWTSA---KNSCSE-NGATLAVIDSEK-DM--IFLKRHV
G-----GAEHWIGLKNG-T--GQTWKWTNGE---EFN-----HW-----------FNLTG
TESCAFL---NSR--E------VS-----SAECGQ-S--LHWVCSRPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------ICPDN-
WISFQNKCYLFSEN--E---SSWNAS---ISDCLT-QQADLTTIDTDQ-EM--NFLKRHK
G-----SYDHWIRLGTT-N--FSARCPINKT---TFH-----SR-----------VNVSG
TEECTYL---TDDVDC------VA-----IARCYT-D--RRWICRKTYY-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREP-------------
---PARARPPPPA-----ARPA-----------------------PAAPRPRS---PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------ETPCPED-
WLLYGRKCYYFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDDFHWVNGD---PFD-----P------DT----FTISG
MGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MERSA-------------SDIY
FTL----------------------------------NFPTAFQAQDNYRPQQNA----F
--------FSRC------------------S-LFYIVAIV-LGLL--NVLLIS--LLL--
YQ-------------WILCKG--------PGD-S----ACASC----------SSCPDF-
WMRYKNHCYYFSVE--K---KDWNSS---LEFCTA-SDAQLLMLMDNQ-EM--SLLQNLI
N-----QDFHWIGLRKN-----SSWRWEDGS---PLNFSRISS--------------NSL
VQRCGAI---SKE--G------LH-----GSSCEV-L--LQWICKKARL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------VSPHFMSMPA
LL----------------------------------RITGRLS-----------------
--------------------------RGK-IH---------------------K------
---DLRKKCLAII-------SPV-----TPAKFCCCILII-FILVALYLVTLSALLAV--
--------------------RSR------------ETDLL----------ILYVSCPKG-
WIGFGSKCFYFSED--S---KNWTFS---QTSCTS-VGAVLAQFETEE-EL--NFLRRYK
G-----IFDHWIGLSRESS--HHAWKWTDNS---KYN-----AS-----------FIITG
DGERGYL---NDL--G------VS-----SARSY-TD--RKWICSKQITFSIS-CTVPMS
PK------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------IQFILS-LK--DFLKRYK
C-----TADHWIGLEIT-E--NQTLQWVNGT---MSK-----KW-----------FPVRG
NEKCAYL---DND--G------AA-----TARCYT-D--RKWICRMQMH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MGRI-SRGSRQ------------RPRPRAVRT---GW-
------------------VVSR-----S----PCGQNR------------GPGRE-A--A
G-----DTTTR----------LLL-G---------AIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQHCHT-HDAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FPISG
LGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MEGEE--------------
----LENRRKRRAE-V--KRKMII----LSVLLCGCLAV-----LL-W----LM------
---------------LRFPRK-------IGIKM--MSKNCTDD---------MRICPPA-
WDLISQKCFFQSEH--E---TTWVEG---QRHCRK-YLASLAKIVSWN-DM--ELLADYL
N----SSSSYWIGLRKHNV--DNIWRWMDGS---HFS-----NW-----------FSITD
SSNCALV---DVS--G------PS-----TTSCNG-T--RKYLCSKKSHCV---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MGE-----------G-DQQ-
-E-------------------------------TFLEHK-------AATEPL--------
-----------GS-WCHGVGRRRSR--VQLIAACAALGA--LILVL-V--VISTAR----
--------------------------------WPVPVPPFPAF---------AHVCPNA-
WVGFQGKCYYFSKE--E---NDWNSS---REHCNA-HGASLATIGSED-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWTWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKAHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------CPT-FVQFLISAR----
--------------------------------WPVPVPPFPAF---------GHACPNA-
WVGFQGKCYYFSEE--E---NDWNSS---REHCNA-HGASLATIGSAE-EM--DFMMRFQ
G-----PANCRIGLHRE-E-EDAQWTWHDAT---AFT-----N---------W--SVCLS
SC--H----------D------FP-----RALFEM-G-TFSWCHSHGFA-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------DTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSPK-EL--EFMFKFT
R------REPWIGLRR-----GDEFHWVNGE---PFD-----P-------D-T-------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MTAA---------------------
----------------------------------------KIK------------EAST-
GLL---K-------------TD--VT------------TPDSLKDVE----IGK------
---KVQGKCLRII-------SAE-----SPAKLYCCYGVI-AVLTVT-VLSLSVALSL--
----------------S---GRP------------VTENSG---------PCYATCPKD-
WIGFGNKCYYFSEE--M---RNWTFS---QTSCMA-LEAHLAIHESQE-EL--NFLKRYK
G-----PSDHWIGLHRESP--EDPWMWTDNT---EYN-----NL-----------VLTQG
GGEYAYL---NDS--G------IS-----SAKDY-IH--KKWICRKSKICT-SQCPEILN
PG------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------PAAR--------------------------------PRPPRPRPRS-PAE-
------------------AEAR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWKAA-----L--EGK-RDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P-------H-T--FAISG
PGECVFV---EPT--R------LM-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DG--
-SL--------------TENS-------------SLHP-----------ENGEQG----N
ATSSHFVTHPEGS----------LQVPVPCAVV---TVAFITSLII-AVIALTVGQ----
YN----CPGQYM-----------------------SLVPSESH---------VTSCSDE-
WVGYQRKCYFFSTM--K---RSWTSA---QSSCLK-HGATLALIDSEK-DM--IFLKQYV
G-----RTEHWIGLNNE-D--GQTWKWSNGK---VFN-----NW-----------FNLTG
SENCAFL---NST--E------VS-----SEECQN-N--LHWICSKPSE-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MA------EPFPAP-------RGDGARRR------
----RRTAVSESS-GCSELRQNRRC--VLCVALCAVLCI--LVSAL-VAVI---VL----
--------------------------------QRPSCPPPPPF---------SHVCPNA-
SIGFQGKCYYFSYT--K---SDWNSS---REHCHR-LGASLATVDTEE-EM--GFIMQYH
G-----PEDHWIGLHRA-E-GDEHWTWADGS---AFS-----N---------W--FKPQG
GGQCVYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVLWRNGTNPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ME-EL--NFLKRYK
G-----PSDHWIGLRRESS--HHIWEWTDNM---EYN-----NT-----------LAIRG
GGECAFL---NDN--G------VN-----SDRIY-IN--RKWICSKPNSYVYS-CQLCPH
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------ME-----------LHLPNH----D
ATSPHFSTRHEGS----------FQVPVLCAIM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSED-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSEK-DM--NFLKRYT
G-----REEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNVTG
SEKCVFL---KNT--E------VS-----SMECEK-N--LYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------MPS----F----------WS-QKSP----K------CLYFYFSGM------
---------------MTKHK--------K------CFIV---GAAL-II--------I--
-------------------TN---------IIAVYVVKLTQDS---------QSFCPYG-
WIGFQNKCYYFSKE--E---GDWNSS---KYNCST-QHADLTIIDNTE-EM--NFLRRYK
C-----SSDHWIGLKMA-K--NRTGQWVDGA---IFT-----KS-----------FGMRG
SEGCAYL---SDD--G------AA-----TARCYT-E--RKWICRKKIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------R-----
-------------------------NNVE-KDIAPSEL----------PANPGY------
---------------LHSKE-HSIKATLIWRLFFLIMF----L----TIIVCG----MV-
---------------A----------ALSAIRANCHQEPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARHYT-E--RKWICSKSDIHV---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MAEA---------------------------------H-
-II--------ETRMNLNEEEK--GAEIE--EVK--MPL----GRRSCRKAPFK------
------KGSFWNNRWCYKSERGEYVIPATCFHSM-ILTM--TVIII-IIILIPAI-----
---------------LLAERK---------NEVCPDL-FPAVF---------ADPCPKG-
WLGYQMKCYYFSVN--E---GNWTSG---NSHCSS-HNASLAVVGSQE-TL--DFFLRYK
S-----PPDHWIGLQKD-S--GQPWRWINGS---IFT-----EGF------FT--LPTEN
GRRCAYL---NHI--A------VA-----SSSCTR-E--ERWVCSKDMFKSIA-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DF--
-SA--------------TETS-------------SLHL-----------KREPQS----H
ATGTYSATYHEGS----------IQVPIPCAVV---NVVFITTLII-ALVALSVGQ----
YN----CPGQHV-----------------------SSAPPNTH---------VFPCSDD-
WIGHKGKCYLISKK--T---KNWTLA---QNFCSK-HDATLAVIDSKE-DM--NFLKQYM
G-----RAEHWIGLRNE-A--GQTWKWSNGQ---EFN-----NW-----------FNLTG
SENCAVL---NSA--E------VS-----SRECDK-N--LHWICSKPSK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SMI----------------------------------ELSTATQAQNDYGPQQKS----S
--------SSRS------------------S-CSCLVAIA-LGLL--TAVLMSICVLL--
YQ-------------WILCHC--------SNY-S----TCASC----------PSCPDL-
WMRYGNHCYYFSVE--K---KDWNSS---LQFCLA-RDSHLLIIRSNQ-EM--SLVKSFL
S-----EAFCWIGLRNN-----SGWRWEDGS---PLNFSRISF--------------NSL
VQTCGAM---NKN--D------LQ-----ASSCEV-L--LQWVLILADQ----TLF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-HC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSMPSDSH---------VSSCSDD-
WVSYQRKCYFISTV--K---RSWTSA---QSACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---EFN-----NW-----------FNLTG
SEKCAFL---KNT--E------VS-----SMECEK-N--LYWICNKPYKS----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------VE--DLKPSSPPYPSPPL---LV
GE----------------------------------RGGNQQK-----------------
------------------------------ARVE----LSGNFVKGT----VFK------
---NRQGKYLRII-------SAE-----SPVKLHCCYGVI-AFLSV-AVIALFVALLL--
---------------------PK------------EVSNK----------NIYYDCPRD-
WIGVGSKCFYFSEK--V---ENWTSS---QTFCMA-QGVQLARFDSPE-EL--EFLERYK
G-----KHDHWIGLHRKSS--EHHWMWTDGT---EYN-----NL-----------TSPRG
EGECAYL---SGR--D------VS-----SGRNY-TH--RRWICSKPNSFTA--SV----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
TT----PNPE----TDT---------------SLP----STPG---------KAECPPG-
WIEVDGNCFFLSTG--T---KDWEGS---KKACEE-HNALLTKLSVL--QM--EVLKSLV
E-----NSNYWIGLKKS-G--DSGWVWNDNS---AFH-----E---------E--FSIRG
AGDCAYL---DST--S------VN-----SASCSQ-H--RRWICCKPPQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MNNP----E------LRDGRADGF------
---------IHR--IICKLKENR--------KTGL-MCF---LIF--IFTVCII------
---------------------------------MIATWYKHAK---------PVACSGD-
WLGVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKAELAQIDTQE-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VY-----SSRGFI-D--IKWICSK--PKYFLY------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SML----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLLS--VLL--
YQ-------------WILCQG--------SNY-S----TCASC----------PSCPDR-
WMKYGNHCYYFSVE--K---KDWDSS---LEFCLA-RDSHLLVIIDNQ-EM--SLLQVFL
S-----EAFCWIGLRNN-----SGWRWEDGS---PLNFSRISS--------------NSF
VQTCGAI---NKN--G------LQ-----ASSCEV-P--LQWVCKKCPF-ADQALF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MPDCLET--------------GEKLLPQH--SPFPKPPSFWNFSLPKD--
------------------------------------TGIRFVH-----------NMNAQ-
CV-------Q------KPEEGN--GP--------------LGTGGVQ----CCK------
---IVQGKCFRII-------STV-----SPVKLYCCYGVI-MVLTV-AVIALSVALST--
----------------K---KTE------------QIIIN----------KTYAACSKN-
WTGVGNKCFYFSGY--P---RNWTFA---QAFCMA-QEAQLARFDNEE-EL--IFLKRFK
G-----DFDCWIGLHRESS--EHPWKWTNNT---EYN-----NM-----------NPILG
VGRYAYL---SSD--R------IS-----SSRSY-IN--RMWICSKLNNYNLH-CQTPPV
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MTLGNKRGRRT-----
---PARSRPSRTTL-TPALTPPLT----LTPTLTPALPL-----TP-SLTLTPTLTP---
------------TPTLTPPLTPTPTLTLAPTPTPPPSPTPTGS---------KVECSLN-
WLEVLGTCFSFSAG--T---ADWKES---NTSCEV-DGAILAMMT-PQ-QM--EILKTHV
G----S-FTYWFGLNKE-G--DSSWKWVDNS---AFN-----NE-----------FTIHG
TGEFAYL---DAT--G------VK-----SDEWLV-K--KKWICSRSPKH----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------K------
---KLQGKCLTLA-------SPV-----TSTKLFCCCLLT-TVLTA-AVVGLSVALLV--
-----------------R-KPEQ------------AIMNH----------TYYSTCPRK-
WIGYGNKCYYFSED--T---RNWTHC---QNSCRA-LGAELTQFESLE-EL--DFLRRFM
G-----PSDHWIGLQRESS--QPAWKWTDNT---EYS-----NT-----------VSIRG
VGEHAYL---NVN--G------IS-----SARQH-ID--RKWICSKPISYSLQ-CQIPTS
F-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SL--------------TENS-------------SLHV-----------ERGQQN----N
AASPHFATYHEGS----------LQVPIPCAVV---NVVIITVLII-ALISLSXXQ----
YN----CPAQNN-----------------------CPEPSNSH---------VSSCQDD-
WIGYQKKCYFISNI--T---RNWTFA---ENSCSE-HNATLALIDSEK-DM--IFLKRYV
G-----RAEHWIGLKNE-A--EQMWKWSNGK---EFN-----NW-----------FNLTG
SGNCAFL---KST--E------IS-----STKCGK-N--LHWICSRPFK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTISG
PGECVFV---EPT--R------LV-----STECLT-T--RPWVCSKMAYT----------
--------------------------------

MEGS---GEGSGGDQTRTQFP-MEPLESQVPKLEPKQVLAE----ERQPESPGSSPS-LA
--------SAVKEAAGASQDLSSGKKLPSPRPAPLKLLPLSLGYGAFRRQASSGSEPP--
------------SPGPAATEQSRDGETPGAELAPRATPG-EPAPGSWAPMELQVDVRVKP
VGAAGGSRAPSPAPSTR-----FL--------------T--VPVPESPAFSRHASPAQ--
---LLLRQTPSPGSTWGRGVPLAVGRAERGLDGEGWASHPEGRAESPGSPTCRCRCK---
--------------EDAVLLPR---AEV--DGDKKLSRVIKLIG-LPMY-----------
---------MKSL-------RWALAVMALL--------L--ALSAV-----AIVAL----
--------------------------------ASKAGARC-------------RPCPPG-
WVWSDDHCYYFSAE--L---QAWEAS---RAFCSA-HHATLPLLNHTQ-----GFLSRYP
V-----TKYSWVGARRG----PRGWHWIDGT---PLL-----PQL-LPEENQD-----EP
DLDCGGLE---GG--K------LV-----ASGCDS-P--RPWVCAKGTK-----------
--------------------------------

MERV---WEAAPGGQAGAEFP-MEPVGSMVPGLEQPQVPEK----ARQPEGPESSPSPV-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPP---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYLSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLL-----PQL-LPEDGKD-----NL
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPVREPPRRSR----PP-P
PPA--------PA--------------------------------ASAPLPRVLS-PGD-
------------------GEGR-----G----QEVLLR------------RSGSG-Y--D
G-----STSWKAA-----L------EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------DAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEASLTVIQSQK-EL--EFMFKFT
R------KEPWIGLRRV----GDEFHWNKLS---SFS-----P------TN-R--FSVSG
HGECVFV---DPT--R------LV-----TSDCLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAREPPSR----------
------ARPP-PP-----LAARPA---------------------PAPAAPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSRPGAPGAG----------
------PAAATLS-----AARAAP---------------------LRPRRPRPRS-PAE-
------------------AEAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FNIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------PSS-------------SAIY
STL----------------------------------ELPTAVQVQDDYRPQRRG----G
GTTEL---NPRP------------------P-LFCLVVIV-LGLL--NILLTS--LLL--
YL-------------WIPGQG--------PSD-S----NRASC----------PSCPDF-
WMRFANHCYYFSVE--K---KDWNSS---LQFCIA-RDAQLLIILDNQ-EM--SLLQNLI
D-----QDFHWIGLRKN-----SSWRWEDGS---ALNFSRVYS--------------NSL
VQRCGAV---NKD--G------LQ-----ASSCEV-P--LRWVCKKVRL-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MTD-------------SVIY
SMI----------------------------------ELPTATQAQNDYGPQQKS----S
--------SSRP------------------S-CSCLVAIA-LGLL--TAVLTS--VLL--
HQ-------------WILYQG--------SSY-S----TCAGC----------PSCPDL-
WMRYGNHCYYFSVE--K---KDWNSS---LQFCLA-RDSQLLIITSTE-EM--SRVKGFL
S-----EAFCWIGLRNH-----SGWRWEDGS---PLNFSRISF--------------NSL
VQTCGAI---NKN--I------LQ-----ASSCEV-L--LQWVLILAD----QTLF----
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------IKAA---------------------
----------------------------------------KDE------------EASM-
GML---E-------------TD--FT------------TPDCLQEVE----IDK------
---KLQDICLRMV-------SPE-----SPAKLYCSYALN-IILTAA-VIALSVALS---
-----------------VRTEKP------------VISTLG---------PCYPTCPSG-
WIGLGNKCFHFSED--M---RNWTFS---QTSCMA-LGAQLAQFDSLE-EL--NFLKRYV
G-----NSFSWIDLQREST--QHPWKWTDNT---EYN-----NL-----------VPVEG
EEKHAYL---TGS--G------IS-----SSRDY-LK--RHWVCSKSNSYT-SQYSGPSS
F-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MEPAQEPPGGSPA--R----
---PGRRRPPRPR-----RP-------------------------PR----AQAA-PPE-
------------------AGDR-----G----PEGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--Q---RDWNTG---RQYCHT-HEAALAVIQSQK-EM--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MK-
---------TLAKGVTK----------IE-NNSP----G------TDK-KKQGL------
---------------MCRYK--------K------HIVC---TLFI-LT-----------
-------------------IN---------VAVSTIVLSVKCR---------QSFCPDG-
WIGFQDKCYYFSEK--E---RDWASS---RDNCTA-AYADLTTIDTDK-EM--SFLSRYK
C-----GSDHWIGLKMT-K--NQTGQWVNGT---PFS-----KW-----------FNVKG
SEECAYL---NDN--G------AG-----TARCYT-E--RRWICRKNIH-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SI--------------TENS-------------SLRP-----------ERGQQS----T
TASPQFATQHEGS----------LQVPIPCAVL---NVVFITCLII-ALIALSVGE----
YN----CPGQCS-----------------------HSVPSNSP---------VSSCSDD-
WLAYRRKCYFISTV--T---KDWKAA---QNFCSE-HGATLAFVDSEE-DM--IFLKRYV
G-----RAEHWIGLKNE-D--GRTWKWSDGK---VFN-----NR-----------FNLTG
SENCAFL---NST--G------VI-----STECER-N--LYWICSKPFK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------VL---SYLI-PSCLI--------
-------------------------------SVLQSGCSPAAQ---------GPACPDG-
WVGYQGKCFYFSEA--E---GNWTYS---RSRCSA-LGSSLTAIDTLQ-EM--DFLLHHK
D-----KSDYWIGLRRD-Q--GQPWKWTNGT---KFN-----HL-----------FGIEG
GGECAYL---NE-N-R------VG-----SLRCTG-E--GRWICSKPDVFTCGWGAGLEP
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MC------
-VTKASLPMLSP------------------------------------------------
------------------------------------------------------------
---------------------T--GS----------------PQEVE----VGK------
---TLQGKCFKII-------CTE-----SPAKFYCCYGVI-VVLTV-AVIALSVALSA--
----------------I---KTE------------QITIK----------NTYAACPQN-
WFGVGNKCFYFSKY--T---SNWTFA---QNFCMA-QEAQLARFDNEE-EL--KFLMRFK
G-----NVDCWIGLHRESS--EHPWKWTDNT---EYN-----NT-----------IPIRG
EERYAYL---NNN--Q------IS-----STRIY-SL--RMWICSKLNSYSLH-CQTTFF
PS------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MMVENFYRAS------------QTS-----
----HVSGHHRTTF-D--AKKLLT----LWTLLCGGVVV-----LL-W----GF------
---------------FSFPRK-------FGTTRITRNKTCDDE---------AKICMNA-
WHKINQNCFFLIQH--E---NSWPVA---KQNCEN-LEAHLAKFNKQN-EL--EALMSLV
N----EGSSYWLGLNKRNL--DKLWLWTDGT---KYN-----DL-----------KEIHD
YGECAFL---HKR--G------ID-----STTCDD-L--KDYICMKVGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MDS-----------E-DC--
-SI--------------TENS-------------SSHL-----------ERGQKD----H
GTSIHFEEHHEGS----------IQVSIPWAVL---IVVLITSLII-ALVALNVGK----
YN----CPGLYE-----------------------KLESSDHH---------VATCKNE-
WISYKRKCYFFSTT--T---KSWALA---QRSCSE-DAATLAVIDSEK-DM--TFLKRYS
G-----ELEHWIGLKNE-A--NQTWKWANGK---EFN-----SW-----------FNLTG
SGRCVSV---NHK--N------VT-----AVDCGA-N--FHWVCSKPSR-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------ME-EL--NFLKRYK
G-----PFDHWIGLRRESS--HRIWKWTDNM---EYN-----NM-----------LAIRG
GGECAFL---NDN--G------VN-----SGRIY-MN--RKWICSKPNNYVYS-CQLCPH
WDTT----------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MRPS----DAL------------------VS--HAV--
PSL----------------------------APPFASSPASLF---------VSYCPKK-
WVGYGGKCYYFSEE--E---KSWNVS---QHFCSS-FNASLAGIDTLQ-EK--DFIMRYA
G-----LVEHWIGLRRE-S--GQPWKWVNGT---Q--------LK-------QQLFEVRA
EGDCAYL---SDV--F------VS-----SSRCYS-V--RNWICSKPDAYMKAKKNAMEG
E-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MQTDTSPRLP------------QTS-----
----HERRHHRLMF-D--AKKVLT----LWTLLGGAVAV-----LL-W----GF------
---------------FSFPRK-------FTVTRTARNKTCDDE---------VKLCPKD-
WNKLRQNCFSRIQH--K---NSWLTA---NDTCEL-HDATLAVFIDKT-EV--EILMNQI
Q----EMKTYWIGLHRQNL--LGIWVWTNGS---KYN-----NL-----------HEIQD
HGQCAFV---HQK--G------ID-----STSCED-Q--KEFICTREGQCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------E-NC--
-FI--------------TENN-------------SLHP-----------ESGQEN----D
ANSPRFSTQRDGF----------FQVPVLCAVV---NVVFITILII-TLIALSVGK----
YN----CPGQYT-----------------------FSVPSDSN---------VSSCPDD-
WVGYQRKCYFISTA--K---KSWTSA---QNACSE-HGATLAIIDSEK-DM--NFLKRYA
G-----RGEHWVGLKKE-P--DQTWKWSNGK---EFN-----DW-----------FNLTG
SEKCVFL---KNT--E------VS-----SMECEK-N--LHWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------CPHG-
WFGYTGVCYYLSRD--S---RSWEQA---QERCSE-LGASLAIL-KDE-AM--DLLFRLR
G-----NVDYWIGLRRR----GERLHWGDGS---SYS-----S---------W--VPVLG
NSQCVYL---ADD--K------FR-----SENCSN-E--RPYVCSKAQAAL---------
--------------------------------

MERV---WEVAPGGQAGAEVP-MEPVGSLVPGLEQAQVPEK----ARQPEGPESSPSPA-
--------RAMKKAAGAGREPSSEKQLPSPRPGTPRVPPLSLGYGVC-------PEPP--
------------SPGPASVKLPRNGEAPGA----------EPAPGAWAPMELQVDVLVKP
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQADPSQ--
---QLLLRTSSLGGTWGRGSTLAAAGTESGRDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELRLEKENAALLPR----AGL--EGEEKLPRAVTLTG-LPMF-----------
---------MKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QACPPG-
WVLSKEHCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGKD-----NL
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSS-----------D-NC--
-YV--------------TENS-------------SLHP-----------ESGQEN----D
ATSPRFSTHREGS----------FQVPVLCAVM---NVVFITILII-ALIALSVGQ----
YN----CPGQYT-----------------------FSLPLDSH---------VSSCPDD-
WVGYQRKCYFISTV--K---RSWTSA---QNACSE-HGATLAVIDSVK-DM--NFLKRYA
G-----GDEHWVGLKKE-P--GHPWKWSNGK---DFN-----NW-----------FNFTG
SEKCAFL---KNT--E------IS-----SMECEK-N--VYWICNKPYK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------THTRLLLSAIA----VSVR-HLG----GD----
--------------------------------EHLASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MC------
-VTKASLPMLSP------------------------------------------------
------------------------------------------------------------
---------------------T--GS----------------PQEVE----VGK------
---ILQGKRHGTI-------SPE-----SCAKLYCYYGVI-MVLTV-AVIALSVALSA--
----------------T---KTE------------QIPVN----------KTYAACPQN-
WIGVENKCFYFSEY--P---SNWTFA---QAFCMA-QEAQLARFDNQD-EL--NFLMRYK
A-----NFDSWIGLHRESS--EHPWKWTDNT---EYN-----NT-----------IPIRG
EERFAYL---NNN--G------IS-----STRIY-SL--RMWICSKLNSYSLH-CQTPFF
PS------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------SNN---
---------------------------VE-KDIT----P------SELPANPGC------
---------------LHSKEHSI-----KATLIWRLFFL---IMFL-TIIVCGMVAAL--
-------------------SA---------IRANCHQEPSVCL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QDADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------LVMKE
DGANLYV---AKVSQV------PRMNPRPVMVSYP-G--SRRVCLFE-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MA------EPSPPR-------EAMACEGE------
----EERQS-------HELRQNRRC--VLCVALCAVLCI--LVSAL-VAVI---VL----
--------------------------------QRPSCPPPPPF---------SHVCPNA-
SIGFQGKCYYFSYT--K---SDWNSS---REHCHR-LGASLATVDTEE-EM--GFIMQYH
G-----PEDHWIGLHRA-E-GDEHWTWADGS---AFS-----N---------W--FKPQG
GGQCVYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVLWRNGTNPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MINP----E------LRDGRPDGF------
---------KRW--TICNFKPNW--------KICLCVCF---VI---IFAACII------
---------------------------------MIVKWPTCDK---------RVACSGD-
WLAVRDKCFYFSDD--T---RNWTAS---KIFCSL-QKSELAQIDTQK-DM--EFLKRYA
G-----TDMHWIGLSRK-Q--GDSWKWTNGT---TFN-----DW-----------FEIIG
NGSFAFL---SAD--G------VH-----SSRGFI-D--IKWICSK--PQYSL-------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------LER--ESSLQ--SFI--TP-------SEYMATPFK------
---MHLNEHFWKGT-----------------------TV--WPILL-TFWFRKLF-----
---------------LSLEKR---------NETCPVL-LPAAL---------AVPCPKG-
WIGYQRKCYYFSET--E---GNWIFG---SRHCSS-HNASLVVIDSQE-EM--EFLLRYK
S-----PPDHWIGLRKD-S--GQLWSWVNVS---LFP-----EQL------LG--LPTEE
GRRCAYL---NHK--G------IA-----SSSCTR-E--EPWICSRKARIHV--------
--------------------------------

MERV---WEAAPGGQAGAELP-MEPVGSLVPGLEQPQVPEK----AQQPEGPESSPSPS-
--------RAMKKAAGAGREPSSERQLPSPRPGTPRVPPLSLDYGVC-------PEPP--
------------SPGHASVKLPRNGQAPGA----------EPAPGAWAPVELQVDVLVKS
VGAAGGSRTPSPRPSTR-----FL--------------T--VPVPESPAFSRQADPAH--
---QLLPRASSLSGTWGRGSTLAAAGTESGRDAEGRASPVEGS--SPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--EGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QPCPPG-
WVLSEEHCYYFSVE--A---QSWEAS---QAFCSA-YHATLPLLRHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGKD-----NP
DINCGALD---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------MS------
-ATKASLPMLST------------------------------------------------
------------------------------------------------------------
---------------------T--DS----------------PQEGE----MGK------
---TLQGKCLRVV-------SPE-----YPAKLHCCYGVI-MVLTG-AVVALSVALSV--
----------------R---TTE------------QISIKN---------NTYSACPRK-
WIGFGNKCFYFSEY--S---SNWTFA---QAFCMA-QEAQLARFDNLE-EL--NFLMRFK
G-----NFDCWIGLHRESL--EHPWKWTDNT---EYN-----NX-----------ISIRG
VERCAYL---NNN--G------IS-----SARIY-AD--RSWICSKLNSYSLH-CQTPLF
PF------------------------------

MEEA---WEAAPGGQAGAELP-MEPVGSLVPTLEQPQVPAK----VRQPEGPESSPSPA-
--------GAVEKAAGAGLEPSSKKKPSSPRPGSPHVPPLSLAA----------------
------------VAGPALVKLPRNGEAPGA----------EPAPSAWAPMELQVDVRVKP
VGAAGGSSTPSPRPSTR-----FL--------------T--VPVPESPAFSRHADPAH--
---QLLLRAPSQG-----------ARTESGCDAEGRASPAEGSAGSPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--DGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QQCPPG-
WVLSEEHCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGED-----NL
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MHDNVEKGFT-
---------------QS--K----LRANPAIRTNCNQKPSVYL---------EAVCPES-
WIGFQRKCFYFSDD--I---KNWTSS---QIFCDS-QGADLVQVETLQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQTWKWINGT---EWT-----RW-----------FPIRG
GGECAYL---NDK--G------AS-----SARHYT-E--RKWICSKPHTYAQMKQQSLN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNS-----------E-DC--
-SL--------------TENS-------------SL-------------ERGRQN----N
AASLHFASHHEGS----------LQVPIPCAVL---NVVIITVLII-ALIALSVGQ----
YN----CPARYM-----------------------FSEPSNNH---------VSSCSDD-
WIGYQRKCYFISNT--T---RNWTLA---QNSCFK-HGATLAVIDSEK-DM--IFLKRYV
G-----RAEHWIGLKND-A--GQTWKWSNGK---EFN-----NG-----------FSLTG
SENCAFL---NST--E------VS-----STDCGR-N--LHWICNKPFK-----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MQSVQIPILKHKVST----------PAEGERLNHFSEH--KAAPEPPAHQRRRIPTGSD
PQ---LPEED-VH-----ISVLESNT----------STPAMG------------G-DQQ-
-E-------------------------------TFLEHQ-------AAPEPLGQ------
----SGEKTQWGS-WCHGTGRRRSR--VQLIAVCAALGA--LILML-VVVVISTVC----
--------------------------------RQVPVPPFPDF---------AHVCPNA-
WVGFQGKCYYLSKE--E---YDWNSS---REHCNA-HGASLATIGSAE-EM--DFMMRFQ
G-----PANCWIGLHRE-E-EDAQWMWSDGT---AFT-----N---------W--FELRG
GGRCAYL---NGD--R------IS-----SSLCHL-H--KHWVCSRADHYVLWKQKVHPQ
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MLSNCVDCEKSSCFGNPVKNC--RILLSRNITLTEKLKMLQG
NS----------------------------------TSEESVE-----------------
--------------------------EGG-SG---------------------K------
---DLQEKCLAII-------SPV-----TPAKLCSCILII-FILVALNVVTLSALVAA--
--------------------RSR------------KPDLK----------VLYVTCPEG-
WIGFGSKCFYFSEE--S---KNWTFS---QTSCTK-MEAVLAQFEMEE-EL--NFLKRYK
G-----PSDYWIGLSRESS--HHAWKWTDNS---KYN-----AS-----------FVITG
DGERGYL---NDL--G------VS-----SARSY-TD--RKWICSKQIMSLNSSRPY---
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MHD-----------S-----
-------------------------NNME-KDIAPSGL----------PANPGY------
---------------RHSKE-HSSKATLIWPLFFLIMF----L----TIVVCG----MV-
---------------V----------GLSAIRANCHQKSSECL---------QAACPES-
WIGFQRKCFYFSDD--T---KNWTSS---QRFCDS-QNADLAQVESFQ-EL--NFLLRYK
G-----PSDHWIGLSRE-Q--GQPWKWINGT---EWT-----RQ-----------FPILG
AGECAYL---NDK--G------AS-----SARYYT-E--RKWICSKPDTYVQMLQQSPN-
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MLTDTSLRQS------------QTN-----
----HERRHHRLMF-D--AKKVLT----LWTLLGGAVAV-----LL-W----GF------
---------------FSFPRK-------FTVTRTARNKTCDDG---------VKLCLKD-
WNKLRRNCFSYIQH--K---NSWYTA---KHNCEL-RDATLAVFIDKT-EL--EILMNQM
Q----EKKTYWIGLHRKNL--LGIWVWTNGS---KYN-----NL-----------HDIQD
HGQCAFM---HKG--G------ID-----STSCED-Q--KESICTREGRCP---------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MNE-----------RCN---
---------------------------VH-KNPE----A------QELPVNQGF------
---------------LSSKR--------CSDSIWKQVLV---ISIT-ICLVTILCGGF--
-------------------LV---------ARAKTQQKPPECL---------QVACPDS-
WIGFQGKCFYFSVD--V---KNWTSS---QRFCDS-QDADLVQIETSQ-EM--DFLLRYK
G-----PSDHWIGLSRE-H--EQPWKWTNGA---EFT-----TW-----------FQIKG
RGKSAYL---NDK--G------AN-----SASSYT-E--RKWICSKALL--QTNQWPQMR
Q-------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------PCE----------
------ARPPP-P-----VSRAPR---------------------AAPHRPRPP------
------------------PPAR-----G----PE-GLLR---------RS--GSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHT-HEAVLAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTIAG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ME--EMRVY-SGLFGVKRS----------KRAVP------
----L-----RENFVTQQVL----------LA----VLF--TALLI-TATAFAVQ-----
-----------------------------------AFQPHTQP---------CFQCPFD-
WIRYRGKCYYFSEV--E---GNWTSS---QDNCSA-LGASLAMLDSME-DL--SFVMRYK
G-----VSERWIGLLRE--DEGQPWQWVNHS---PL------SH--------P--FLIRG
GGLCAYL---DDN--G------LS-----SSHCST-E--RSWICNKHELQSSGKGNRVRR
PPN----LCVSS--------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------AACPEG-
WVGYGGKCYYFSEK--E---GNWNSS---RNNCSS-FGASLAGIDSLQ-EK--AFLLRYK
G-----LPDHWIRLRRK-Q--DQAWKYPNNNVPITFS-----SR-----------FEVSG
EGECPYL---NQK--T------VG-----SSRCYT-K--RNWIFSKP-------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------FKTMSF
WH----------------------------------MDTDCLK-----------------
-------------------------------GIDV---LIFIF--------SGK------
---KLQGKCLRIV-------YPE-----SPAKLYCCYTVI-AVLAA-AVIALSVALSV--
----------------K----KE------------QISIN----------NTYAACPRD-
WIGFGSKCFYFSEN--T---SNWTFS---QTFCME-REAQLARFDSLE-EL--NFLKRYK
G-----NFDYWIGLRRNSP--EHPWRWTDNT---EYN-----SL-----------VPIRG
VEEHAYL---NNN--G------IS-----SARVY-AD--RRCICSKPNSYTLQ-CRIPFS
SF------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------ILVPL-RG-------------------GSC-------QTLQPTKSVLAKKSA
PPAPLCPQPG-PS-----L-----PL----------SPHTMGA-----------V-PHL-
-HG--------------AKGER--ERR------SPSPPR-------EATAREGD------
----EERQSQRGS-GCSELRQNRHH--VLCVA---VLCI--LVLAL-VAVI---VL----
--------------------------------QRLSCLPPPPF---------SHVW----
------KCYYFSYT--K---SDWNSS---REHCHR-LGASLATVDTEE-EM--EFMRGYR
R-----PADRWIGLHRA-E-GDEHWTWADGS---AFS-----N---------W--FELRG
GGQCAYL---HGD--W------IN-----STLCHS-E--KFWVCSRADSYVL--------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MDSQRGA-KDANLSLRCIK--DKLLPIAG--------TVL-VAALLIAVI----
--------------------------------AL----AAAPH---------LPGCPND-
GIGVGLQCFYFVED--A---ADWDGG---QRFCLS-RGAQLAAVGTPQ-EL--GFVLRYG
R-----SVQYWIGLRRD---RSGPWMWANGS---LFN-----N---------A--FSIEG
SGRCAHT---DGG--G------IG-----SAECSR-P--KRSVCSRPQRGGAEL------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------PAPGAARPRS-PAE-
------------------AQAA-----G----PRGLLR------------RSGSG-Y--E
G-----STSWK----------AAL-EDTTTRLLLGAIA----VLLFAILV----VM----
--------------------------------SILASKGCIKC---------EAPCPED-
WLLYGRKCYFFSEE--P---RDWNTG---RQYCHS-HEAALAVIQSQK-EL--EFMFKFT
R------REPWIGLRRV----GDEFHWVNGD---PFD-----P------DT----FTISG
PGECVFV---EPT--R------LV-----STECLM-T--RPWVCSKMAYT----------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------WFVFFRLL------AFL-VIALCCMLA----
----------------S--E----L----SILEKAKPLPEFPI---------AAPCPDD-
WIGFREKCYYFSED--T---RNWTSS---QSFCSS-RSASLTGIDTQR-EM--DLLLRHK
G-----PSDHWIGLSRE-P--GQDWKWTNGT---KFT-----GW-----------FEVKG
RGECAYL---NDE--R------VS-----SARSYT-D--RRWICSKPGFYA---------
--------------------------------

MEES---WEAAPGGQAGAELP-MEPVGSLVPTLEQPQVPAK----VRQPEGPESSPSPA-
--------GAVEKAAGAGLEPSSKKKPPSPRPGSPRVPPLSLGYGVC-------PEPP--
------------SPGPALVKLPRNGEAPGA----------EPAPSAWAPMELQVDVRVKP
VGAAGGSSTPSPRPSTR-----FL--------------K--VPVPESPAFSRHADPAH--
---QLLLRAPSQGGTWGRRSPLAAARTESGCDAEGRASPAEGSAGSPGSPTC---CRCK-
-------ELGLEKEDAALLPR----AGL--DGDEKLPRAVTLTG-LPMY-----------
---------VKSL-------YWALAFMAVL--------L--AVSGV-----VIVVL----
--------------------------------ASRAGARC-------------QQCPPG-
WVLSEEHCYYFSAE--A---QAWEAS---QAFCSA-YHATLPLLSHTQ-----DFLGRYP
V-----SRHSWVGAWRG----PQGWHWIDEA---PLP-----PQL-LPEDGED-----NL
DINCGALE---EG--T------LV-----AANCST-P--RPWVCAKGTQ-----------
--------------------------------

Query Results

"ENSGT00710000106527"

ENSGT00710000106527