Query Results 

-------------------------------------------------MQAKYSSTRDM
RGMLDDDEDTTLSLHSQASATTW-------QP--------EP-------RPTEL-RTP--
---LSTWRPVALTLLTLCLVLLTGLA--ALGLVFFQFYQLSNTQQAIIVQKEE-------
---------------------------RLGNLSQQLQSLQGKNKKLAESLHRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGPKCSPCPEKWKWLGDKCYQ
FYRD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCNAENSTMLKINTQEVL-------------------DFAMHQS
YSEF---FYSYWTGLS-RNGSG--KTWLWMDG----T---PYSFELFEI--IIDTS----
----LLRSRDCVTILNGKAF--------------SKDCRELRR---CACERTAGRVD-PE
KLH-----------------------------------------------------

-------------------------------------------------MQAKHSSAR--
-DMLEDDADTATSLYSRASTALQ--------A--------ES-------GRSDA-RTP--
---SSAWRPVALTLLTLCLVLLVGLV--VLGLLFFQFYHLSNTQQDSISQQEE-------
---------------------------SLRNLSRQLRSLQVQNGEL-------AE-----
------------------------------------------------------------
---------RLCR-ELYNRS-------------------GEHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYLCIAENSTMLKINSQEKL-------------------DFAMPHS
YSEF---FYSYWMGLS-RNSSG--KAWLWTDG----T---PRSSELFEI--MIDAS----
----TSRHRDCVTILNGRAF--------------SKDCRELRR---CACEKKAGSVV-AE
HLL-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLGVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSTG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------MEYP--
-LDVDEDGYTKLNFHSRGATRR-------------------PVGSKKG------S-----
PVASPPWKLIAMILGILCLVILVIAV--VLSSL---AFWRSN----------S-------
----------------------RSNPLEKDNSLSRNKE------HQTQPTKSSLEE----
------------------------------------------------------------
---------NVVS-TKALKT---------------T-GA---VPSNCPPNWIVHEKSCYL
LAIS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWYGSKRRCSQLGSHLLKIDTLKEF-------------------DFIVEQM
SSY---AIHSFWIGLS-RNQTE--ELWLWDDGS-------TFSYNLFQ---------ISS
TATQENTAHNCVWIHVGNAY--------------DQPCNIPSF---SMCERLLSG-----
--------------------------------------------------------

---------------------------------------------------MDYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEK-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------GV---LSSPCPPNWIIYEKSCYL
FSPS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDQSKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
--MQEEETYTSLQWDNLTQN-----------IYQ------------KH-------QS--S
TKYSGTWCLLIAVLCIVFIGSSAASI--FLGFKWFQLSAITVEQHEKLIQQDMMLLNF--
--------T-------RWKKKFDF-----------------QMKYCLNLTGNLSSA----
------------------------------------------------------------
-----------------------------------------QTQNPCPENWTHNGKSCYF
VFEQ--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WKSWNTSKDQCLKEDANLLQIDSQEEM-------------------VFVTRSL
RTI--KHEFGYWVGLS-QEGLS--QPWVWQDG----S---SPPHDLLPK-----------
-QRSQSGDLMCGYLSRNLLS--------------SSNCTNWKY---FICEKNMFSYF-F-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTQKPSLIS------------------------V------GHAS--
---SSWWRVMALILLILCVGMVIGLV--ALGIWSAM------------------------
------------------QQ-------------N---YLQDENENLSEALQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQA----------EQKGT--F-KDHKCSPCDTNWRYYGGSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEDSKQYCIDMNSTLLKIDNQNIQ-------------------EYI----
KTRT---RLIRWVGLS-RQKSD--EVWKWEDG----S---VLSQNM----FE-----L--
-LEDGKENMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGKAN-VD
ELP-----------------------------------------------------

---------------------------------------------------MKYHSHI--
-ENLDEDGYTQLDFSTQGIHKR-------------------PVRSEKG------SRAP--
---SSPWRPIAVGLGILCFVAVVVAA--VLGAL---GEYGHN----------S-------
----------------------GRNPEEKDNFPSRNKE------NH-KPTESSLDE----
------------------------------------------------------------
---------KVAP-SKASQT---------------T-GV---FSQPCHPNWIMHGKSCYL
FSFS---G

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWYGSKRHCSQLGAHLLKIDNSKEF-------------------EFIESQT
SSH---HINAFWIGLF-RNQSE--GPWFWEDG----S---AFSPNSFQ---------VRN
TAPQDSLLHNCVWIHGSEVY--------------NQICNTSSY---SICEKEL-------
--------------------------------------------------------

------------------------------------------------------------
--MQEEETYTSLQWDNPTPN-----------HYE------------KI-------LP--S
TKCSGTWCLVVVISCIFCIGSFASSI--FLGIKLFQVSAIVKQQQEKLIQQDTALLNF--
--------T-------QCRRGHDL-----------------QEKELQTLMQNSVS-----
------------------------------------------------------------
----------------------------------------AHNCSPCPTNWIQHRGSCYR
VFEN---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KIWNSSKEDCWKESSRLLQIDSKEEM-------------------DFITGTL
KKI--KRDNSYWVGLS-QNGLN--GPWLWQDG----S---SPSPDLWSF-----------
-QKTQSTNNVCGYLKDKELF--------------QANCSNWKY---FICEKYALRSL-V-
--------------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVRSNWDGNNLRKG--------E------HVAQ--
---SSIWRGAALSLMTLCLLLVAGLV--TLGIIFLQMSND----------ITS-------
---DSEKLNQLQKIIHPQQDNLSEPLNISRNGPSEE-YLQSQISALLERQEQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHT-------------------SDHKCNPCPKSWQWHGNSCYY
FTIH--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWSDSRKDCTDKNATLVKIDSFRER-------------------NFL----
QSQPSLPLSFFWLGLSWNSTG---RHWVWEDG----S---TPSPTLFSYQEQ---ARF--
-----NGSRGCAYFERGNVY--------------ISRCSAEIS---WICEKTASLVK-IE
DLV-----------------------------------------------------

-------------------------------------ALKCC-VNQELSRTMESRSEV--
-ENLDEDGYTQLDFHSQGITGR-------------------PVILKKV------TWAT--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 154)

SPRWRPIAVTLGILCLLILVIAV--VLGTM

ENSGT00700000104266_Linker_0_2 (154, 367)

VYEAIWRSN----------S-------
----------------------GSNPLKNDNFPSRNKE------NHSQPTQSSLED----
------------------------------------------------------------
---------RVAP-TKAPTT---------------T-GA---FSSSCPPNWIIHKNSCYL
FSTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LASWNRSKRQCSQLHSNLLKIDSAEEL-------------------EFIERQM
SSQ---PDNSFWIGLS-RQQTE--GPWLWEDG----S---VFSSNLFQ---------IRS
TEAQENSSHNCVWIHLSIIY--------------DQLCSMPSY---SICEKTL-------
--------------------------------------------------------

------------------------------------------------------------
------MTLD-------DLKSNS----MKDQPDE-------KSNGDKAEGPRSL------
---STRWRPAALILGLLCLGLLVTVI--LLIIQLSQVSDLLKQQKVKLTHQEDILEGQAL
AQRQAEKSS--QESQREL-EMIETLAHKLDEKSKKLMELQQQNLNLQKALEKAAN-----
------------------------------------------------------------
------------------------------------------FSGPCPQDWLWHEENCYK
FSSG---PF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWEKSRENCLSLDAQLLKINSTDDL-------------------EFIQQTI
A----HSSFPFWMGLS-LRKPN--NSWLWEDG----T---PLMPHLFR---------LQG
AASQMYPSGTCAYIHRGIVF--------------AENCILNAF---SICQKRANLLR-AQ
--------------------------------------------------------

---------------------------------------------------MEYQSPL--
-ENVDEDGYTQLDFSSHNLTRR-------------------SVVSEKG------PCAA--
---SPYWRPITVTLGILCLLMLVIAV--VLGT---MAIWRSS----------S-------
----------------------GNNMLKNDSFPSRNKN------NQSQPTQSSLEE----
------------------------------------------------------------
---------GEDT-TKALPT---------------T-GV---LSSSCPPNWITHENSCYL
FSTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWNRSKRQCSQLGSYLLKIDSSKEL-------------------EFISRHV
SSQ---PDHSFWIGLS-HSQTE--GPWLWEDG----S---MLLSNLFQ---------IRS
TVTQKESSHNCVWIHVSDFY--------------DQLCSVPSY---SICEKKLSI-----
--------------------------------------------------------

-------------------------------------------------MQTKFSSTR--
-DMLDADGDTTMSLHPRTSTTTQ-------RP--------EP-------GHPEH-RPP--
---SSAWRPVALTLLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDSISQKEE-------
---------------------------RLGNLSQQLQSLQTQNRKLAETLHHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RSSSS--KAWLWMDG----A---PYSSELFEI--IIDIT----
----SLRNRDCVTILNGKAF--------------SKDCRELRR---CACERTAAAVK-LQ
RL------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQASATTR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--ALGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNTSQELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------EFAASQS
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFTSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCKELKR---CVCERRAGMVK-PE
SFHVPPETLGEGD-------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRDGNNLRKR--------G------HPAP--
---SPIWRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYC
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWANSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGS-KCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DSD-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLADD-DTTISLYSGASTANR-------CA--------EP-------RHSEN-ETP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNTQQDSIAEQEG-------
---------------------------RLGNLSRQLQSLQSQNRRLVDTLQNVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCLTDNATMLKISTQEEL-------------------DFGMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERMAGRVV-PE
VLQQVA--------------------------------------------------

-------------------------------------------------MWTDFFTYS--
-SMSEEVTYA-------DLQFQNSSEKEKIPE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLTLLCLLLLIGLG--VLASMFH----------VT---LKI-------
---EMKKMNKLQNISEELQRNVSLQLMSNMNISN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------KLCR-ELYSKE-------------------QEHECKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

HTWQESKMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--RSYDYWLGLS-PEEDS--THGMRVDN----I---INSSAW----VIRNAPDL-N
N-------MYCGYISRLYVQ--------------YYHCTYKQR---MICEKMANPVQ-LG
SIYFREA-------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNLKPQKPVLTS------------------------A------DPAS--
---PSWWRVTALVLLVLSIGMGVGLV--SLGIISVT------------------------
------------------QQ-------------H---YLLAEKENLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-DLILDL----------EQKTK--SRSEHRCSPCAANWRFWGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESQRYCSQRNATLVKTASQSVL-------------------EYI----
KDRT---ISIRWIGLS-RQNSN--KVWMWEDG----S---VFLPNM----FD-----L--
-SSDRRENMNCAYFHNGKIY--------------PASCEDRHF---LMCEKKAGVMK-VD
QLL-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIKT----MKDHPDE-------KSNGKKA---KGLPFLY--
---SPWWCPVAVTLGVLCLGSVVIII--KLGVELSQVSDLLTQQQANLTHQKNKLERQIS
ARQQAEEAS--QESQKELKEIIETLAQKLNEKSKEQMELHQQNLNLQETLKRAANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHKESCYL
FSSG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LDWKKSQENCLSLDAKLLKINSTADL-------------------DFILQAA
S----HSSFPFWIGLS-RRNPH--YPWLWEDG----S---PLMPYLFR---------LRG
AISQTYSLGTCAYIQQGTVF--------------AENCALVAF---RICQKKANLLR-AQ
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-D----------TYQ------------KC-------LS--S
NKCSGACCLVMVISCVFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSCAL-----------------QMKYCQAFMQNSLSS-A--
------------------------------------------------------------
-----------------------------------------HNSSPCPNNWIQNRESCYY
VSEI---WSI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--KGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERSQSANQVCGYMKSNSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MHEEELYSSLQWDIPTSE-----------ASQ------------KC-------LC--S
SKCSGTWCVMTVISCVFCVGLLATSI--FLGIKFFQVSSLAMSQQERLIQQDIALLNL--
--------T-------EWQRNYIL-----------------EMKNCQALQQRSPRS----
------------------------------------------------------------
----------------------------------------DCNCSHCPHNWTQNGKSCYY
VFQI---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QKKWNGSKEICLNEDARLLQIDSKEEM-------------------NFILHSI
RM---TKEFGYWVGMF-QDELS--QSWFWQDG----S---SPLPDFLPT-----------
-ERQLSASQICGYLKDHSLF--------------SDTCNNWKY---FICEKNALRSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MSNEVTYA-------TLTFQDSAVAGNNQDGNNLRKR--------G------YPAP--
---SPIWRQAALSLLTLCLMLLIGLV--TLGIKFLQTSNE----------INS-------
---DSEKLSQLQNIIHQQQENLSQQLDNYRNFPMEEEFLKSQIADLLRRQGEMAI-----
------------------------------------------------------------
---------KLCQ-ELVIHN-------------------SGHKCNPCPRTWQWYQNSCYY
FTTN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWVNSRKDCMDRNSTLVKIDSLEEK-------------------NFL----
ISQPLPKLSFFWLGLFWDPIA---RSWFWEDG----S---IPSPSLFNTQER---IQI--
-----NGSKECAYFQKGNIY--------------ISRCSAEIF---WICEKTAALVK-IE
DLD-----------------------------------------------------

---------------------------------------------------MEYQSSV--
-ENLDEDGYTQLDFSSRNITRR-------------------SVVSEKG------LCAA--
---SSHWRLIAVTLGILCSVMLVITV--VLST---SGIWRSS----------S-------
----------------------GNNLLKSDSFPSRNKD------NQSQPTQSSLED----
------------------------------------------------------------
---------SVIP-TKALTT---------------T-GV---FSSSCPPNWITHEDSCYL
FSTL---LD

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWDGSKRQCFQLGSHLLKIDSSKEL-------------------EFISRQV
SSQ---PDHSFWIGLS-RRQTE--EPWLWEDS----S---TLLSNLFQ---------IRS
TVTEKDSSHNCAWIHVSDIY--------------DQLCSVHSY---SICEKKLSV-----
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------LQISNE----------INS-------
---DSEKLSQLQKIIHQQQDNLSQQLGNDNNFPVEEQFLKSQISNLLKRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELISHI-------------------SDHRCN-----LQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWTNSRKNCIDKNSTLVKIDSLEEK-------------------DFL----
KSQPLPMFSFFWLGLSWDPSG---RSWLWEDG----S---IPSPSLFSTKEL---AQI--
-----NGSRGCAYFQKGNIY--------------ISCCSAEIS---WICEKTAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLAFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPI

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFTTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DLD-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGASTVTR-------RA--------EP-------RHSEN-ETP--
---SSVWRPVALTLLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDSIAEQEE-------
---------------------------RLGNLSRQLQSLQSQNRRLVDTLQNVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCLTDNATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERLAGRVV-PE
VLQQ----------------------------------------------------

-------------------------------------------------MHAKYSSTK--
-DMLDDDGDTTISLHSRASTTTR-------RP--------GP-------EHTEH-QAP--
---SSVWRPLTLTVLTLCLVLLIGLA--ALGILFFQFYQLSITQQDSISQKEE-------
---------------------------RLGNLSQQLQSLEAQNRKLAATLQRMAE-----
------------------------------------------------------------
---------NLCR-ELYNKT-------------------GEHRCSPCPGKWKWRGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SRSWQGCEYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNSSG--KDWLWMDG----T---HYSSELFDI--VIDFT----
----SIRSRDCVTILNGKAF--------------SKDCRELRR---CACERTAAAVR-PE
WLY-----------------------------------------------------

-------------------------------------------------TELTCSPRK--
-AMQDEDGYVTLNIKTQKPALTSEY---------------KPMP--TV------EPAP--
---SPLWRVMALTLLVLCVGMVVGLV--ALGLMLSLYFEQNKNEYSGIT-----------
-----WKHNNRGH-SPVMQQ-------------N---YLQAENENLSGTMKLL-VK----
------------------------------------------------------------
---------KVCQ-DLIQLS----------GQK-Q-----SHKCNPCDTHWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWEESKKYCIDVNATLVKISSKSILVE---------SICQFYSEQYF----
NSRT---GLIRWIGLS-RQKSS--DVWRWEDG----S---VLSKTI-HR-LK-----L--
-SGTGTENMNCAYFHNGNIH--------------PTFCENRHY---LMCERKAGVVK-VE
HL------------------------------------------------------

-----------------------------------------------------FFRYL--
-SMSEEVTYA-------DLKFQNSTETENIQE---MDK-----FGEKA------PPAP--
---SRVWRPAALFLTLLCLLLLIGLG--VLGSIFY----------IT---LKI-------
---EMEKVNELKNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTTAT-----
------------------------------------------------------------
---------KLCR-ELYREK-------------------KEHKCKPCPKGWMWHEDSCYF
LSDN---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKTACADQNASLLKINNKSAL-------------------EFI----
KSQN--KLYQYWLGLS-PQSYY--TSGKSIDD----I---INSSDW----VIRNASDL-T
N-------MYCGYLNGLYVQ--------------YHFCTYKTR---MICEKVADPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPSLIS------------------------V------GHAS--
---SSWWRVMALILLILCVGMVIGLV--ALGIWSAM------------------------
------------------QQ-------------N---YLQDENENLSEALQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQA----------EQKGT--F-KDHKCSPCDTNWRYYGGSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCIDMNSTLLKIDNQNVQ-------------------EYI----
KART---RLIRWVGLS-RQKSD--EVWKWEDG----S---VLSQNM----FE-----L--
-LEDGKENMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMAN-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MSEDVTYA-------TLTFQDSVAAGNNQDRNNLRKR--------G------YPAP--
---SSIWRQAALGLLTLCVMLLIGLV--TLGIMFLQMSSE----------INS-------
---DSDKLTQLQKIIHQQQDNLSQQLSKYRNFPVEEEFLKSQISSLLKRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHKCNPCPKTWKWYQTSCYY
FAVN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWPNSRKNCMDKNSTLVKIDSLEEK-------------------DFL----
RSQPLPKFPFFWLGLSWDPSG---RSWLWEDS----S---RPSPSLFSAYEY---AQI--
-----NESKGCAYFQNGNIY--------------ISRCSAEIS---WICEKTAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVAYA-------HLKFPESRKTETVQE---LHR-----VGTKA------CPAH--
---SHTWRQTAFTLTLICLLLLIGLG--ILGSIFY----------TT---LKI-------
---ETEKLNKLENFKEELQRNISLQLIANMNKSE-------NIRNLSIALQDLAT-----
------------------------------------------------------------
---------KLCR-ELNREE-------------------PGHKCKPCPNSWMWYKNNCYF
LSET---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQEGEISCSAQNASLLQIEENSTL-------------------EFI----
KSKK---LYSYWLGLP-PKQDD--KNSEEVDE----N---IISSDK----LKRN---MDK
--------MHCRYIYGTKFF--------------YASCTEKYK---VACEKKANSVK-VE
SVITSEDTDGRI--------------------------------------------

-----MKVHLFYSLNTNIVSHYCENVTNFSSFTNLLQTTRGVICSSLLCGLLSYQSTS--
-DMHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--S
NKCSGAWCLVMVISCIFCMGLLTASI--FLGVKLLQMSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSQENCLKEGSTLLQIESEEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERSQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DSAS--
---SSWWRVMALILMILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGA--V-KGHKCSPCDTNWRYYGDNCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSTG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKN-LRA-Q-
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKSKT----VKDQPEQ-------KPDGEKA---KGLQFLS--
---SRWWCPVSVTLGILCLGLLVTTI--MLIMQLSQVSDDLQQQQANLTQQEHILEGQIL
ARRQAEKSS--QESQRELKDMIETLAHKLDEKSKELRELRLQNLNLQEALKKAAN-----
------------------------------------------------------------
------------------------------------------FSGPCPQDWLWHEENCYL
FSSG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LNWEKSQENCLSLDGQMLRINSTDDL-------------------EFIKQAS
A----HSSSPFWMGLS-RRKPS--HPWLWEDG----S---PLKPHLFR---------LRG
AVSQEYPSGTCAYIQGGAVF--------------AENCILTAF---SICQKKANLLR-AQ
--------------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSQSNTRI-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRSN----------S-------
----------------------GSNTLENGYFLSRNKE------NHSQPTQSSLED----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCWQLGSNLLKIDSSNEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

-------------------------------------------------MQPKYSSTR--
-DMLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMEE-------
---------------------------RLGNTSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTDQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWEDCKYFCLSENCTMLKINKQEDL-------------------DFAMFQS
RSPF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPETLGEGD-------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

---------------------------------------------------MEFHSGL--
-ENVDEDGYTQLVFNSRVTTRT-------------------CVLSEKG------TR-T--
--VSPPWRLMAVTLGVLCLVILVVAV--VLSAL-GEYWLRSN----------S-------
----------------------GSQPLKNDNFPSRSRE------NHNQPTKSSLEE----
------------------------------------------------------------
---------NVAP-TTALKT---------------T-GF---FSSSCPPNWIMHETSCYL
FRTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DTWNGSKRQCSQLASHLLKIDSSEEL-------------------EFIEREM
SFQ---PVHSFWIGLS-RSQSG--SPWLWEDG----S---TFSSNLFQ---------IRS
TATRESSSHNCVWIHMSVVY--------------DQLCNVPSY---SICEKQLSL-----
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTQKPALTS------------------------G------DPAS--
---SSLWRVMALILLILSMGIAAGLV--ALGIM---------------------------
---------------SVTQQ-------------K---YLQAENEHLSGTLKQL-AR----
------------------------------------------------------------
---------KFCQ-DLLQQS----------RQKEK-----GHKCSPCDINWRYYGDSCYG
FFRH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NLTWKDSKKYCADVNATLLKITREDTL-------------------QYI----
SSRT---GLIRWVGLS-RQKPS--DVWMWEDG----S---VPSKNX-XX-X---------
-XXDCNRNMNCAYFHNGKIH--------------PTFCENKHY---LMCERKAGMAK-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPIWRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAV-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
TSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKAQKPALT------------------------SV------EPAS--
---SPLWRVMALALLVLCVGMVVGLV--ALGLM---------------------------
---------------SVMQQ-------------N---YLQAENENLSGTLKML-VK----
------------------------------------------------------------
---------KVCQ-DLIQLS----------GQK-E-----SHKCNPCDTHWRYYGDSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKKYCIDVNATLVKITSKSIL-------------------QYL----
NSRT---GLIRWIGLS-RQKSS--DVWRWEDG----S---VPSETV----LK-----L--
-SGTGTEHMNCAYFHNGKIH--------------PTFCENRHY---LMCERKAGTVK-VE
QLL-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRDGNNLRKR--------A------HPAP--
---SP

PF08391 // ENSGT00700000104266_Domain_2 (126, 361)

MWRHTALGLLTLCLMLLIGLV--TLGIMFLQISNE----------INS-------
---GSEILSQLQKTVDQQQDNLSQQLGNSNNLSTKEEFLKSHISSLLNRLEQMAV-----
------------------------------------------------------------
---------KLCQ-ELIVHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLRFSFFWLGLSWNSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKRCAYFQKGNIH--------------ISRCSAEIF---WICEKTAVPVK-IE
DLD-----------------------------------------------------

--------------------------------------------------------ME--
-CNLDEDGYTQLDFNSRGVTRR-------------------PLVSEKG------NCAA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 161)

SPCWRPCAVTLGILCLVILVIAV--VLGTV---VIRR

ENSGT00700000104266_Linker_0_2 (161, 367)

SN----------S-------
----------------------ESNPLQNGNFTSRNKK------NHSQTTQSSLEE----
------------------------------------------------------------
---------SVVP-TKKPTK---------------APTTTKVFSSLCPPNWITYEKSCYI
FQTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 465)

-PQSWRRSKRQCSQMGSNLVKIDSSEEL-------------------EFIVKQV
SSQ---PDNSFWIGLS-RNQTE--GPWLWEDG----S---TFSSD---------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNVKTEKPALTS------------------------G------APAA--
---SSLWRVMALILLVLCIGMVFGLV--ALGIL---------------------------
---------------SITQQ-------------H---NLRAENEHLSGTLKQL-AR----
------------------------------------------------------------
---------KVCQ-DLIKQS----------GQE-E-----RHQCSPCEKNWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKKYCIDTSATLLKIPSQNIL-------------------QYL----
TSRT---GLIRWVGLS-RQNSK--EAWMWEDG----S---VPSKNV----IK-----F--
-SGNGTENMNCAYFHNGKIH--------------PTFCENKHY---LMCERKAGMPK-VD
QLL-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLAAATLGVLCLGLVVTIM--VLGMQLSQVSDLLTQEQANLTHQKKKLEGQIS
ARQQAEEAS--QESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHGENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------VRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLTFQDSVGARNNRDRNNLRKR--------G------CPAP--
---SP

PF08391 // ENSGT00700000104266_Domain_2 (126, 361)

IWRQAALSLLTLCLMLLIGLV--TLGIMLLQTSHE----------INS-------
---DSERLSQLQKTIHQQQDNFSQQLSDYRNFPTGEEHLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIRT-------------------SDHKCNPCPKMWQWYQNSCYY
FATN--EENTWVNSRNNCLDQNSTLVKIESLEEK-------------------DFL----
KSQPLPKFSFFWLGLSWDPSG---KSWLWEDG----S---IPSPSLFSPREY---TQI--
-----NGSRGCAYFQKGKIY--------------LSRCSAEIS---WICEKTATLVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPIWRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAV-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 464)

EKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
TSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLYVSNY---------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
---MDEDGYTQLDFGTRNIHKR-------------------PVKSEKG------SPAP--
---SSRWRSIAVALGILCLLTVVVAA--VLGAL---AFRRFN----------S-------
----------------------GRYPEEKDNFPSRNKE------NH-KPTEPSLDE----
------------------------------------------------------------
---------KVAP-SKASQT---------------T-GV---FSGPCLPNWIMHAKSCYL
FSFS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

ENSWYGSRRHCSQLGAHLLKIDNAKEF-------------------EFIESQT
SSH---RVNSFWIGLS-RNQSE--GPWFWEDG----S---AFTPNSFQ---------VRN
TAPQESLPHNCVWIHGSEVY--------------NQMCIASSF---TICEKEL-------
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIHT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSHLLKQQQANLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLTRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAQLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--S
NKCSGAWCLVMVISCIFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSLSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-EISQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MNSEMTFD-------DFKNKT----MDDQPDQ-------EPNGKKA---KGLHFLS--
---SRWWCPTAVTLGILCLGLLVTLI--ILTMQFLQVSDLLKQQQANLTNQEIILEGQIL
AQHQTEKAS--QESERELKKKIETLTQKLDENSKKQMELHQQNLNLQEALRKAAN-----
------------------------------------------------------------
------------------------------------------FSGPCPQDWLWHEENCYR
FSSG---PF

PF00059 // ENSGT00700000104266_Domain_2 (370, 530)

NWEKSQENCLSLDAQMLKINSTDDL-------------------EFIRQAS
A----HSNFPFWMGLS-LRKPS--SSWLWEDG----S---PLTPHLFR---------LQG
PVSQIYPAGSCAYLQRGAVF--------------ADNCILTAF---SICQKKANLLR-PQ
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSGQTEDIQR---FDT-----LGEKA------TPAP--
---SRVWRQTALALTLLCLLLLIGLG--VLGSMFY----------IA---LKT-------
---EMEKVNKLQNIKEELERNVSLQLVSNLNISQ-------KIMNLSSTMQEIAT-----
------------------------------------------------------------
---------KLCY-ELYRRQ-------------------AEHKCNPCPKKWLWLENNCYR
LSDD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SVTWQKSKELCSAEKASLLMIKNKSIL-------------------EFL----
KFN---RLRGYWLGLS-PRNDS--PSYQTLDD----I---FVSSKR----DMRNTDYISN
G-------IYCGYLDNVYLY--------------FTTCAGQKK---FICEKSANPVK-IE
STLMIKVPEESV--------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPALIS------------------------V------GSAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QR-------------N---YLQGENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVVKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTDMNATLLKIDNRNIV-------------------EYI----
KART---HLIRWVGLS-RQKSN--EVWKWEDG----S---VISENM----FE-----F--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

----------------------------------------------------KCHNLT--
-LLLLTNQWS-------A--------RTGKYHDQNM-------TASSS------SSAH--
---SHIWRLLSLLVLILCLLKLIGLA--LFGIRWIMVTNDVRGQEGMDEWLTV--RGT--
--TVHFKIDN-LTGKKGSHKAFTGRLEHL----------SSQNSNLSAALREMST-----
------------------------------------------------------------
---------KLCQ-GITRNQ-------------------PEYNYEPYPERWICARDNCYY
LSMV---

PF00059 // ENSGT00700000104266_Domain_2 (368, 463)

TKKWGESRKSCEALNSTLVKIDNKEEL-------------------DFV----
SSNL---QFCHWVGLL-RKKDS--NQWKWVDG----S---TLSPEL--------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKP---TLS---------------------SA------DS-A--
---SSWWRVIALILLMSSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------R---YLLTEKESLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIWQI----------ELKTK--NTYEHKCSPCASRWRYYGDSCYG
FFRQ---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

NRTWEESKQYCAEQNATLVKAANQRTV-------------------EYL----
TNRT---TSVRWIGLS-RQNSN--KDWMWEDG----S---ILPKNM----ID-----L--
-SGNPGENMNCAYLYNGKIY--------------PASCEDRHY---LMCERKAGLTR-MD
QLL-----------------------------------------------------

------------------------------------------------------------
--MQEEDAYASLQWDPPTPS-----------PYQ------------KH-------LS--S
IKYSGAWCLVVVISCVLCVGSVTTSV--FLGIKLFQVSTIAMKQQEKLIHQDRELSNF--
--------T-------QWKRNHNL-----------------QMKCCQTLRQKSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCNPCPDNWIQNGGSCYR
VFEN---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KFWHTSKEDCLKEGSNLLQIDSKEEM-------------------DFITDSL
SNV--KKGYDYWVELS-HDGLS--RPWLWKDG----S---PPSPSLSPV-----------
-QTLQSTDQLCGYLKDKFLS--------------STNCSNWKY---FICEKYVLRSS-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DHAS--
---SSWWRVMALILLILCMGMVIGLV--ALGIWSAM------------------------
------------------QQ-------------N---YLQDENENLSEALQQL-AT----
------------------------------------------------------------
---------RFCQ-YVIKQA----------EQKGT--F-KDHKCSPCDANWRYYGGSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCIDMNSTLLKIDNQSVQ-------------------EYI----
KART---RLIRWVGLS-RQKSD--EVWKWEDG----S---VLSQNM----FE-----L--
-LEDGKENMNCAYFHNGKML--------------PTFCENKHY---LICEKKAGKAN-VD
QLP-----------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GSNSLENGYFPSRNKE------NHSQPTQSSLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GL---LSSPCPPNWIIYEKSCYL
FSLS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQVGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--APWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLGVLCLGLVVTIM--ALGMQLSQVSDLLTQQQANLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLARKLNEKSKEQMELHYQNLNLQETLKRVANCS---
------------------------------------------------------------
-------------------------------------------

PF05473 // ENSGT00700000104266_Domain_2 (344, 533)

-APCPQDWIWHEENCYL
FSSG---SFNWEKSQEKCLSLDAKLLKINNTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------VRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAT-N----------TYQ------------KC-------LS--S
NKCSGAWCLVMVISCIFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSLSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 482)

IWHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKM--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPAEVCW-----------
-ERSKS----------SAFF--------------SSNCST--------------------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPW

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WCLAAATLGVLCLGLVVTIM--VLGMQLSQVSDLLTQEQANLTHQKKKLEGQIS
ARQQAEEAS--QESQNELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHGENCYL
FSSG---SFNWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------VRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

---------------------------------------------MTAQVTAASGFWE--
-FLNLEMTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSTG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DPKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGHIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQEALKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSMG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

FNWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
------MIFD-------DFKSKT----MKDQPDQ-------WTDGGKA---KGLRCLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 173)

SQRWCPVAVTLGILCLGLLVTIV--MLAVQLSQVSDLLKQQQANLTHQE

ENSGT00700000104266_Linker_0_2 (173, 367)

NILEGQSL
AQKQEEKAF--RELQRKLKEMNENLTQELEEQSKKQMELHHQNLNLQEALKKAAN-----
------------------------------------------------------------
------------------------------------------FSGPCPQDWLWHEKNCYQ
FSPS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LFNWEKSRENCLSLDAQMLIINSTYDL-------------------DFIKQLT
A----HSSAPFWTGLS-KRKPS--SSWSWEDG----S---PLMPNVFR---------FRA
-LSQRNPSDTCVYIQKGNAF--------------AESCILTAN---SICQKKATLLR-AQ
--------------------------------------------------------

-------------------------------------------------MQTKYSSERDV
RDMLDDDEDTTMSLHSRASTLTW-------RP--------EP-------RHTEL-RTP--
---LSTWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNIQQAIITEKEE-------
---------------------------RLGNLSQQLQSLQVKNKKLVDTLQRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGPRCSPCPEKWKWHGDKCYQ
FYRE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCSAENSTMLKINAQEVL-------------------DFSMLQS
YSEF---FYSYWTGLS-RNGSG--EAWLWMDG----T---PYSFQLFEI--IIDAS----
----NLRSRDCVTILNGKAF--------------SKDCRELRR---CACERTAGRVD-PE
KLH-----------------------------------------------------

-----MKVHLFYSLNTNIVSHYCENVTNFSSFTNLLQTTRGVICSSLLCGLLSYQSTS--
-DMHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--S
NKCSGAWCLVTVISCIFCMGLLTASV--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSQENCLKEGSTLLQIESEEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-EISQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQNSSETEKIQE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLTVLCLLMLIGLG--VLGSM---------------------------
---SMKKMNKLQNVNEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---F

PF00059 // ENSGT00700000104266_Domain_2 (369, 447)

RTWQESRMACVAQNASLLKINNKNAL-------------------EFI----
KSQS--MSYSYWLGLS-PKKDD--SYSMSVDN----I---IDSSAW--------------
------------------------------------------------------------
--------------------------------------------------------

-------------------------------------------------MQPKYSSTR--
-DMLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMEE-------
---------------------------RLGNTSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTDQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWEDCKYFCLSENCTMLKINKQEDL-------------------DFAMFQS
RSPF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPEKLGEGD-------------------------------------------

------------------------------------------------------------
------MMCD-------DFKMKT----MKDQPDQ-------KLNGEKSKGC---HLL---
---SRFWRPAAVILGIICLALLTTTV--LLG-VLSQVSALLKQQQGNLTRQEHVPEGQMS
AQRQVEGAS--QES--ELNEMIEFLAQKLEESSRKQMELHHQNLNFQEALKKAANFS---
------------------------------------------------------------
--------------------------------------------GPCPQDWIWHEENCYQ
FSSS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-PSSWEKSQESCRSLDAQLLKINSSADL-------------------EFIQQAS
A----HSSFPFWMGLF-LRKLS--NSWLWEDG----S---PWMSSLFK---------LRG
AVSQMYPSGTCAYIQRGVAY--------------AESCNLSAF---CICQKKANLLR-A-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPQKPAVSS------------------------A------DPAS--
---SSWWRVMALILLILSMGMVVALV--ALGFMSIT------------------------
------------------QQ-------------N---NLQAENENLSGTVQKL-AK----
------------------------------------------------------------
---------NFCQ-HIIQQL----------EENQK--RSADHKCSPCDPNWRYHGDSCYG
FFRK---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKRFCFNQNATLVKTTSKNTL-------------------DYI----
KDRT---VFIRWIGLS-RQNSD--KVWLWEDG----S---VLSENM----LE-----Y--
-FEDGEENMDCAYFHNGKIH--------------PTFCKNRHD---LICERKAGTMN-VY
LLL-----------------------------------------------------

------------------------------------------------------------
------MTFD-------G-KMKS----VNEQPDQ-------KSCHKKA---KGLLFLL--
---SPWWCPAAMVLIIVCLGLSVTLI--LQWMQLLQVSDLLKQYQANLTHQEHILEGQIL
AQQQATNAS--E---KKLKETIDTLTLELQEKSKEQEKLLQQNVNLQEALQRAENFSE--
------------------------------------------------KKL---------
----KETIDTLTW-ELQEKSKEQEKLLQQNVNLQEALQRAENFSGPCPEDWLWHKENCYL
FSSE---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

SYWTKSQETCLSLDAQMLQINSVDDL-------------------NFISQAT
S----HSTSPFWMGLH-RKKQN--EPWLWENG----S---PLRPHLFK---------IRG
IPSQTHPSGTCVYIQEGAVF--------------ADNCILTAF---SICQKQAKLLP-MH
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPALVS------------------------V------GPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENHTGALQQL-AK----
------------------------------------------------------------
---------RFCQ-YVVKQS----------ELKGT--F-S-HKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEDSKQYCTDMNATLLKIDNRNIV-------------------EYI----
KART---RLIRWVGLS-RQKSN--EVWKWEDG----S---VISENM----FE-----F--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPQKPAISS------------------------V------DRAS--
---SSWWRAMALILLFLSTGMVCGLV--TMGLMSVM------------------------
------------------QR-------------H---NLQVENENLSGKVQKL-AK----
------------------------------------------------------------
---------NFCQ-HIIKQL----------EENQK--RSANHKCSPCETNWRYHGDSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQFCFNWNASLVKTASKNTL-------------------DYI----
KDRT---VFIRWVGLS-RQNSD--KVWLWEDG----S---ALSKNM----LD-----F--
-IGDGRENMDCAYFHKGKIY--------------PTFCENRHF---LICEKKAGMMN-VD
ILL-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DILDADGDTTMSLHSQASTTTQ-------RP--------EP-------GNTEH-QPS--
---SSAWRPMALTLLTLCLLLLIGLA--ALGLLFFQFYQLSNTQKDSISEKEE-------
---------------------------RLGNLSQQLQSLQAQNRRLAETLQRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPQKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 530)

-SKSWKGCEYFCISENSTMLTINTRQVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSG--EAWLWMDG----A---HYSPELFEI--IIDFT----
----SLRNRDCVTILHGKAF--------------SKDCRELRR---CACERMAATVE-PE
RLH-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDEDTTMSLYSQASATTR-------QP--------EP-------RCTGH-RAP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLLFFQYYQLSNTHQDTISHMEE-------
---------------------------RFGNISQQFQSLQVQNTKLTESLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCPEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCRSENSTMLKIDTKEEL-------------------EFAMSQS
YSEF---FYFYWIGLF-RPGGG--KVWLWMDG----T---PYTSELFHV--MIDVT----
----SPRSRDCVAILNKMIF--------------SKDCQELKR---CVCERRAAMVK-PE
SLHFLPETSGEGD-------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNVKTRKPALTA------------------------V------EPAS--
---SPWWRAVALILLILCMGMVVGMV--ALGIMSVT------------------------
------------------QQ-------------N---YLQAQNENLSGTLQRL-AK----
------------------------------------------------------------
---------HVCQ-NLLKQL----------EKEGT--F-IGHKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTDMNATLLKIANQNIL-------------------QYL----
KTRT---SLIRWIGLS-RQNSD--DVWRWEDG----S---VLSKNM----FE-----L--
-SGDGKENMNCAYFHNGKIY--------------PTFCKNKLY---LMCERKAGMAK-FD
QLL-----------------------------------------------------

------------------------------------------------------------
------MIFD-------D-KMKP----VNEQPDQ-------KLCHNKA---KGLRFLF--
---SPWWCPVAMTLVILCVGLSVTLI--IQWMQLLQVSDLLKKYQANLTHQEHTLEGQIL
AQQQAANTS--Q---KKLKETIDTLTWELNEKTKEQEELLQQNQNLQKALQRAADFSGTG
EEERDN---LTLQRRNG-------------------------------------------
-----------------------------EMHLLRTHLFYYHYLGPCPQNWLWHKEHCYL
FSSA---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QSSWAKSQENCLSLDAQLLQINSIDDL-------------------SFILQAT
S----HSTSPFWMGLH-RKKKN--DPWLWENG----S---PLRPHLFR---------IRG
IPSQTHPSGTCVYIQGGGIF--------------ADHCILTAF---SICEKQ--------
--------------------------------------------------------

----------------------------------------------------MEYPDL--
-ENLDEDGYTQLRFSSQNNTRI-------------------SVVSEKG------SCAA--
---SPPWRLIAVILGILCLVTVVTAV--VL---GTTAIWRSH----------S-------
----------------------GSNPLKDGHFPPRNKE------NHSQPTQSSLEE----
------------------------------------------------------------
---------SVTP-TKAIKT---------------T-GD---RSSPCPPNWIIHENSCYL
FSTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLDSNLLKIDNSKEL-------------------GFILKQV
SSQ---PDNSFWIGLS-RTQTE--GPWLWEDG----S---TFSPNLFQ---------IRT
TATQENSSLNCVWIHVSIIY--------------DQLCSVPSY---SICEKKFAM-----
--------------------------------------------------------

------------------------------------------------------------
--MSEEITYA-------NLKFQDFDKKDNIQE---LDI-----CGPKV------PPAP--
---SHLWNKTVLALSFLCLLLLIGLG--VLGGMFY----------AT---LQA-------
---HMAELSRLQNAEEELQRNVSAQMLHNSNSSA-------EISKLSSSLQRLAT-----
------------------------------------------------------------
---------SLCR-ELYKKE-------------------PEHKCKPCPKSSVWYKGSCYF
QLSD---A

PF00059 // ENSGT00700000104266_Domain_2 (369, 529)

HAWQASERLCSAQNASLLTIEDKSTL-------------------EFI----
KSSN---LYHVWLGLS-PTYNY--IDHVTIDE----K---IFS----------SKCNLSE
--------LYCGYVNGNYVS--------------YSACSRKKS---VMCLKTASEVK-VM
NMLMSNSLEGSM--------------------------------------------

------------------------------------------------------------
--MSEEVMYA-------DLKFQDSSKGENIHE---FDT-----VGIKG------------
---------------------------------VY----------TT---LKI-------
---EMGKLNKLQNFKEELQRNVSLQLIHNMNSSK-------MIRDLSITLQEIAT-----
------------------------------------------------------------
---------KLCH-ELYKRE-------------------PEHKCKPCPKTWMWHEDNCYI
LIDN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-YETWQESVMFCSAQNASLLTIKNKSVL-------------------EFI----
KSKR---LRNYWLGLT-TGKYP--TNYQRLDE----T---IFSSNW----LLRNRNDVND
R-------TYCGYVDSMYVY--------------YTDCTSKMS---FMCEKLANPVK-IE
STLMSEIPDGKYS-------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLAAVTLGVLCGGLVVTIM--VLGVQSSQVSDLLTQQQANLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------VRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKP---TLS---------------------SA------DS-A--
---SSWWRVMALILLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------R---YPLAEKESLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIKQS----------ELKTK--NTAEHKCSPCASRWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWEESKQYCAEQNATLVKAASQGTV-------------------EYL----
TSRI---TSVRWIGLS-RQNSN--KDWMWEDS----S---VLPKNM----ID-----L--
-SGNPRENMNCAYLYNGKIH--------------PASCEDRHY---LMCERKAGLPR-VD
QLL-----------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCVA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GSNSLENGYFPSRNKE------NHSQPTQSPLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSPS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHMSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQASATTR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNMSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------DFALSQS
YSEF---FYSYWTGLL-RPDSG--KTWLWMDG----T---PFPSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CVCERRAGMVK-TE
SLHFPPETLGEGDWFS----LCNYK-------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAVAGNNRNGNNLRKR--------G------YPAP--
---SPIWRQAALCLLILCLMLLIGLV--TLGIMFLQTSNE----------INS-------
---DSEKLSQLQKIIHQQQVNSSQQLDNYKNFPMEEKFLKSQIADLLKRQGQMSI-----
------------------------------------------------------------
---------KLCQ-ELIIRI-------------------SDHKCNPCPRTWHWYQNSCYY
FTTN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 457)

EEKTWINSRKDCKDKNSTLVKIDNLEEK-------------------DFL----
KSQPLPKFSFFWLGLSWDPSA---RSWLWEDG----S---IPSPSL--------------
------------------------------------------------------------
--------------------------------------------------------

-------------------------------------------------MQAKYYSTN--
-NMLDEEWGTTLSLHSQASTPAQ-------RP--------KH-------GHTEQ-PPP--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 159)

SSAWRPVALILIILCLVLLIGLA--ILGFVFFQFY

ENSGT00700000104266_Linker_0_2 (159, 367)

QFSNTQKDSINKLEE-------
---------------------------RSGNLSQHLQSLQAQNRKLVETLQQVVE-----
------------------------------------------------------------
---------KYCR-ELYNKT-------------------GEHRCSPCPENWKWHGDKCYQ
FYKK--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQDCDSFCIAENSTMLKINTQEVL-------------------QFAMPQS
YSEF---FYSYWIGLS-RNGSD--KPWLWVDG----A---PYTSELFKI--KTDFT----
----SPGDGDCVTILSGMFF--------------SKNCEELRR---CACETVATPVK-LE
RLP-----------------------------------------------------

------------------------------------------------------------
--MSDEATYT-------TLMLQDSAGVRGNQDANNLRKE--------E------CPAQ--
---SPLWRGAALSLMTLCLMLVTGLV--TLATMFLQVSND----------INS-------
---DSEKLSELQKIIHPQQDNLSESLNNSRKGLTEE-SLQSQISALLERQGQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHA-------------------SDHKCNPCPKTWQWHGNSCYY
FSAN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKSWRDSRKDCTDKNATLVKIDSIEER-------------------DLL----
QSQLSLTFSFFWLGLSWDSSS---RNWLWEDG----S---LPPPTLFNEKEL---ASF--
-----NGSRECAYFERGNIY--------------VSRCSAEIS---WICEKTASLVK-IE
DLE-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPIWRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGPKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MQEEEVYTSLQWDTPPPN-----------LYQ------------KH-------LS--S
TKYSGTWCLVMVILCIFCVGSLATSI--FLGIKLFQVSTIAKKQQENLFQQDTALSNF--
--------T-------QGKGNRDL-----------------QMEYCQNLMQNSFS-----
------------------------------------------------------------
---------------------------------------LCHNCNPCPDNWIQNGERCYH
VFET--

PF00059 // ENSGT00700000104266_Domain_2 (367, 461)

-WKIWQISKQDCLKKGSNLLQIDSKEEM-------------------DFITGSL
RMI--KSDYDYWVGLS-QEELG--QSLFWQDG----S---SPSPN---------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNVKTRKPALTS------------------------V------EPAP--
---SPCWRVVALILLVLCMGMVVGMV--ALGITSVT------------------------
------------------QQ-------------N---YLQAQNENLSGTLQQL-AK----
------------------------------------------------------------
---------HVCQ-NLLKQL----------EKEGT--F--SHKCSPCDTNWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCADVNATLLKIPNWNIL-------------------QYL----
KART---SLIRWIGLS-RQNSH--GAWMWEDG----S---VLSKNM----FE-----L--
-SGDGKENMNCAYFHNGKIY--------------PTFCKNKLY---LMCERKAGMAK-LD
QLL-----------------------------------------------------

------------------------------------------------------------
------ATFD-------DLKNKT----MKDQLDQ-------KPNGQKA---KG-HFLY--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 173)

SPWWCPVAVTLGILCLGLLVTII--VLIMQVSQVSDLLKQQQANLTHQE

ENSGT00700000104266_Linker_0_2 (173, 367)

NILEGQIL
AQKEEEKAS--QESQRELKEMIETLTQKLNEKSKKQMELFHQNLNLQEALKKAAN-----
------------------------------------------------------------
------------------------------------------FSGPCPQDWLWHEEHCYL
FSSN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SFNWEKSQKDCLSLDAQMLIINSTDDL-------------------EFIKRAS
A----HSSSPFWTGLS-LRKPS--HSWLWED-----S---PLMPHVFR---------LQG
AVSQRYPSGTCVYLQRGAVF--------------ADNCILNAF---SICQKKATLLR-AQ
--------------------------------------------------------

-----------------------------------------------MWLHAKDSSTR--
-DMLDEDEDTRMSLRSLASITTG-------RP--------EP-------QRAAH-RAP--
---CSAWRPVALALLTLCLILLTGLA--ALGLVFFQFYQLSNAQQDSISEKEE-------
---------------------------RLGNLSRELHSLQVQKGKLEDTLQLVAE-----
------------------------------------------------------------
---------KLCR-ELYDKT-------------------GEHRCSPCPEKWKWHGDKCYQ
FYRE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 530)

-SKSWQDCGYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGST--MAWLWMDG----T---PYSSELFEI--VIDFT----
----SLRSRDCVTILNGKAL--------------SKDCKELRR---CACQSPAARVR-PE
CLR-----------------------------------------------------

------------------------------------------------------------
--MSLEMTFG-------DLKKKS----MKDQPDK-------KSFGKKV---KGRRFLS--
---YPC

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WCPAAMTLGILCLGLLTTII--MLKKQIFQISDLLEQYQANFTHQENALEGQLL
AYRQAENDS--QSSQ---------------------------------------------
------------------------------------------------KELREIIANLQQ
KLD--------------EGHKEQKELHQLNLNLQDALARKENCSGPCPQDWIWHGENCYL
FSSG---LFNWEASRKNCSALGAQLLKINNTSDL-------------------DFIKQVI
S----HSNLPFWTGLS-LRKPD--NSWIWEDG----S---PLRPHLLK---------FRG
AFSHMYPSGTCAYIQWGDVF--------------ADNCILVAA---RICQKAADLLH-IQ
--------------------------------------------------------

------------------------------------------------------------
------MTFE-------DLRSTT----VKDQPDQ-------KPNGEKA---KGLHHLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 156)

SRRWCPVAVTLGTLCLGLLVTVI--MLIIQLSQVTDLLKQQQANFTHQEDILEGQIS
AQRQAQKSS--EESQKELREMIEILAHKLDEKSQKLTELQQRKMNLQEALKQAANFSXXX
XXXXXXXXXXXXXXX---------------------------------------------
--------------------------------------------XXX-------------
--------XXXXXXXXXXXXXXXXXXXXXXXXXS------------------

PF00059 // ENSGT00700000104266_Domain_2 (413, 463)

-EFIQQAT
A----HSSFPFWMGLS-LRKPS--NSWLWEDG----S---PLMPHLFR---------IQG
AFSQMYPSGTCAYIQRGIVF--------------AENCILTAF---SICQKKANLLR-AQ
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDEDTTMSLYSQASATAR-------RP--------EP-------RCTGH-KAP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLLFFQYYQLSNTHQATISHMEE-------
---------------------------RFGNISRQFQSLQVQNTKLAESLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCNPCPEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKIDTKEEL-------------------EFAMSQS
YSEF---FYFYWIGLF-RPGGG--KVWLWMDG----T---PYTSELFHV--MIDVT----
----SPRNRDCVAILNRMIF--------------SKDCRELKR---CVCERRAAMVK-PE
SLRFLPETSGEGD-------------------------------------------

---------------------------------------------------MEYRSEP--
-ENLDENGYTQLDFSSRNIARR-------------------PVFSEKG------TYRA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 152)

SPHWRCIAVTLGILCLVMLVIAV--VLG

ENSGT00700000104266_Linker_0_2 (152, 367)

TT---GIWRFN----------S-------
----------------------GSNPLKNNNFPSRNKE------NHSRPTQSSLEA----
------------------------------------------------------------
---------SVAP-TKALTT---------------T-GV---LSSSCPSNWIIHETSCYL
FSTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-TDSWESSKRQCSRLGSNLLKIDSSKEL-------------------EFVRKQV
SSQ---PDNSFWIGLS-RHQTE--GPWLWEDG----S---MFSSNLFQ---------IRS
TVSQENSSHNCVWIHMSIIY--------------DQLCSVPSY---SICEKQLSI-----
--------------------------------------------------------

---------------------------------------------------MEYRSSL--
-ENLDEDGYTQLDFSSRHITRR-------------------SVDSKKG------PCAP--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 156)

SPCWRPVAVTVGILCLVMLVTAV--VLGT---

ENSGT00700000104266_Linker_0_2 (156, 367)

MAIWRSS----------S-------
----------------------GNNPLKNDNFPSRNKE------HRSQPTQSSLEE----
------------------------------------------------------------
---------SMAP-TKAL-----------------T-GI---LPSSCPPHWITHENSCYL
FRTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LDSWDGSKRQCSQLGSHLLKIDSSKEL-------------------EFISWQV
SSQ---PDHSFWIGLA-RRQTE--GPWLWEDG----S---MFLPDVFQ---------IRS
TVTQEDSSHNCVWIHVSDTY--------------DQRCSVLSY---SICEKKLSI-----
--------------------------------------------------------

------------------------------------------------------------
-------------------------------------------------------HRP--
---SPAWRPVALVLLTLCLVLLTGLA--ALGLVFFQFYQLSNAQQDSISQKEE-------
---------------------------RLGNLSRQLQSLQTQNRKLAETLHHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEMWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SRSWQGCEYFCIAENSTMLKINTQEVL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSR--KAWLWMDG----A---PYSSELFEI--IIDFS----
----SLRSRDCVTILNGKAF--------------SKDCRELRR---CACERRAARVE-LQ
ELHSLSE-------------------------------------------------

------------------------------------------------------------
--MSEETVYA-------NLKFQDSDKKENTQK---SKR-----CGRKV------PSSP--
---SHSQHNAVLILTLLCFLLLIGLG--VLGGLFY----------TT---LKT-------
---EMIKSNQLQNIKEELQKNVSLQLMHNFNSSK-------KIRNLSAMLQKTAI-----
------------------------------------------------------------
---------QLCR-ELYTKE-------------------PEHKCKPCPKGSKWFKDSCYS
KLDG---FG

PF00059 // ENSGT00700000104266_Domain_2 (370, 530)

TWQKSEMLCSARNASLLKIKNRNEL-------------------EFV----
KSEG---LNGYWLGLS-PRKNY--IRSEILNE----N---MFLSVG----FERSTFDLRK
--------MYCGYIEGIYVH--------------YTYCTLEKS---IICEETAGNVQ-VE
SVLNDLPQESG---------------------------------------------

-------------------------------------------------SKSKKNKGK--
-DMQDEDGYITLNFKSRTTAVTSEH---------------E-EPYYLV------ESAA--
---SPVWRPMALTLLFVCLGMAAGLV--TLGIMFIKFIQFFSIKMKSFD-----------
-----SSSFILGL-FHRILQ-------------V---ERTMKIENLSEILQKV-AK----
------------------------------------------------------------
---------NFCQ-ELIQK-------------------SVGHKCNPCDVNWRYHGDKCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWTESKQYCAKRNATLPNILSNDVL-------------------DFI----
KGRI---SSTRWIGLS-R-NSD--GNWVWEDG----S---PLSKDL----FE-----L--
-LGNG-ENQNCAYFQRGKIY--------------TSVCENIHY---LMCEQSKFRTP-PG
EYQ-----------------------------------------------------

------------------------------------------------------------
-----------------------------MHVSTLCPC-----WFSTE------HPAR--
---SPAWRWSALGLLTLCVLLLLGLA--SLGILYWHHPL---GLVAKKNI----------
--------E----QLTGVEKNLSLQLDISANISK---EKDLIQSNHSFALKKVAT-----
------------------------------------------------------------
---------KLCR-ELTSIK-------------------QDHACKPCPENWHWHRDSCYW
KTS----VL

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NLDESRKVCAERNSSLVKIENKEEL-------------------VYV----
ASKL---KAYHWLGLT-RNISS--DQWVWEDG----S---TLSPDLIEIFPERN------
-----QRNWKCAFAYLHKFL--------------LDNCNGNHP---SICEKAAGPVK-MS
W-------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPI

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQGNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DLD-----------------------------------------------------

-------------------------------------------------MQPKYSSTR--
-DMLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMEE-------
---------------------------RLGNTSRELQSLQVQNIRLSGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTDQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWEDCKYFCLSENCTMLKINKQEDL-------------------DFAMFQS
RSPF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPETLGEGD-------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNFKSRTSIVTSV--------------------------------DP--
---VFSWRPMALTLLFVCLGLTAGLV--TLGIMFFKQQDYLPT-----------------
-----------------------------------------QNGNLSEILQKV-AK----
------------------------------------------------------------
---------IFCQ-G--SK-------------------VVDHKCYLCDNNWRYHGDKCYG
FFRH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NLTWAESKRYCTERNATLLKITSQDTL-------------------DFI----
KGRT---SYIRWIGLS-RRNSD--GIWFWEDG----S---SLSKSV----FN-----L--
-LGNE-KDQHCAYFLKGKIY--------------TSLCEDKHY---LMCERKTNIVR-ID
QL------------------------------------------------------

------------------------------------------------------------
--MQVEEVYTSLQWDSSPPN-----------HYE------------KP-------LF--S
NKCAGMWRVMVMVSCILCLGSLAASF--YLAIKLFQISTIAAKQQENLIQQERELLNF--
--------T-------QWKRKQDR-----------------LMKCCQTLMGNSVSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPDNWIQNGERCYY
FSRQ--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WQVWRRSKELCFKEDAKLLQIDNKEEM-------------------DFITSIL
K-N--KNGDQYWVGLS-QEKRS--GLWFWQDG----S---SPPPALWSI-----------
-QKLQSVNQGCGYLKDKALF--------------NADCSNWKY---FICEMTLSTV----
--------------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSSRVRSKQDGNNLRKE--------E------HPAQ--
---SSIWRGAALSLMTLCLLLVTGLV--TLGIIFLQMSND----------INL-------
---DSEKLNQLQKVIYPQQDNLSEPLNISRKGPSEE-YLQSQISALLERQWQMAT-----
------------------------------------------------------------
---------KLCK-EFLTHT-------------------SDHKCNPCPKTWQWHGNSCYY
FTTH--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKSWSDSRKDCTDKNATLVKIDSFKER-------------------DFL----
QSQPSLTLSFFWLGLSWNSTV---RHWLWEDG----S---SPSLTLFSYQEH---ARF--
-----NRSRGCAYFERGNIY--------------ISRCSAEIF---WICEKTASLVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQNSSETEKIQE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLTLLCLLMLIGLG--VLASVFR----------IT---LKI-------
---EMKKINKLQNISEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQIVAT-----
------------------------------------------------------------
---------KLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKMACAAQNASLLKINNRNAL-------------------EFI----
KAQS--RSRDYWLGLS-PERDY--ISAESVDN----I---INSSAW----VIRNAPDL-N
N-------MYCGYINFSYVQ--------------YYYCTYKKR---MICEKMANPVQ-LD
FIHFREA-------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQASATTR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--ALGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNTSQELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------EFAASQS
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFTSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCKELKR---CVCERRAGMVK-PE
SLHVPPETLGEGISPR--KEICPHLRFISELPSPIFPSERLKTRKKQRISTHTSHR

---------------------------------------------------ME---YQ--
-ETLDEDGYTQLDFRTRGILKR-------------------PVESEKG------SRSS--
---SLPWRPIAVALGILCLVALVVAV--VLGVL---GE--FN----------S-------
----------------------GRNPEEKENFPSRNKE------NH-KPTKSSLDE----
------------------------------------------------------------
---------KVAP-SKASQT---------------T-GL---YSGPCPPNWIIHEKSCYL
FKTS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QNSWAGSKRYCSQLGAHLLKIDNSEEF-------------------EFIESQT
SSH---HINAFWIGLS-RKQTE--GPWLWEDG----S---PFIPNSFQ---------IRD
TASQESLLHNCVWIHGSEVY--------------NQVCNISSF---SICEKQL-------
--------------------------------------------------------

-----MSPALYWLQDLAVI-----------SGAERTELPNAM-SIHGLSRTMDYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCVA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GRNSLENGYFPSRNKE------NHSQPTQSPLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSPS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
------MTCE-------DLKIKT----MKDQPDQ-------KPNAE---KARGPHFLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 173)

SPWWFPATVTLGILCLVLLVIIT--MQRMQLSQMSGPQKQQQANLTHQE

ENSGT00700000104266_Linker_0_2 (173, 367)

NTSEGQML
TQQQ-EEAS--QDSKTKLQEMIKTLVEKLDDKSKMLMEFQHQNLKLQEALKKAA------
------------------------------------------------------------
-----------------------------------------HFSGPCPQDWIWHEEDCYL
FSPS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-PYDWEKSQADCLSLDARLLKISSMEDL-------------------KFIKKAS
A----HSGFPFWIGLS-LRKPS--DSWFWEDG----S---PWKPQLFS---------IQD
G-SKTYSSGTCAYLQRGIVY--------------ADNCILVAF---SICQKKANLTA-QG
--------------------------------------------------------

------------------------------------------------------------
--MSEDVTYA-------TLKVQDSSGTRNNLDGNNLRKT--------G------FPAP--
---SPTWRHAALGLLTLCLMLLIGLV--TLGIMFLQISNE----------VNS-------
---DSEKLSQLQKIIHQQQDNLSQQLGNDNNFPVEEEFLKSQISSLLKRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELISHT-------------------SDHRCNPCPKTWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWFNSKKNCRDKNSTLVKIDSLEEK-------------------NFL----
KSQPLPMFSFFWLGLSWDPSG---RSWLWEDG----S---IPSPSLFSTKEL---AQI--
-----NESRGCAYFQKGNIY--------------ISRCSAEIS---WICEKTAAPVK-IE
DLD-----------------------------------------------------

---------------------------------------------------MHSKNNL--
-EILDEDGYTQLNFNLRDITRR-------------------PMVSKKG------IQAA--
---SPPWRLIAVIAGTLCLVLLVVAA--VLGAL---GEYGSN----------S-------
----------------------GRRPVESDSFPSRSHE------NY-KPTKSSLSK----
------------------------------------------------------------
---------TVAP-SKVPQT---------------T-GY---FSPSCPPNWTVHERSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWNGSRRQCSQLGSSLLKIENSKEF-------------------DFIKNQL
SLH---GAHSFWIGLS-RLPPE--GPWLWVDS----S---AFSSGLFP---------IRS
TETEKNSLHNCAWIHGSEVY--------------NQVCNVASF---SICKKQLS------
--------------------------------------------------------

-------------------------------------------------VWIDFFTYS--
-SMSEEVTYA-------DLKFQNSSETEKVQE---IGK-----FGEKA------PPAP--
---SHVWRPAALFLTLLCLLMLIGLG--VLGSMFH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSRS--TSYPYWLGLS-PEKDY--SYGTIMDN----I---INSSAW----VIRNASDL-S
S-------MFCGYINRIYVH--------------YDYCTYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPI

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQQQDNLSQQLGNSNNLSIEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHA-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWTNSRKDCIDKNSTLVKIDTLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-TE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQNSSETEKIQE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLTVLCLLMLIGLG--VLGSM---------------------------
---SMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWQESRMACAAQNASLLKINNKNALLGCEVTETLYTYLKIIIGKEFI----
KSQS--TSYPYWLGLS-PEKDY--SYGMSVDD----I---INSSAW----VIRNASDL-N
N-------MFCGYINRIYVH--------------YDYCIHRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
------MTFE-------DLKAKP----MKDHPDE-------QSNRKKG---KGLGCLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 158)

SPWWCLAAVSLGIVCLGLLVTIA--MLGMQLLQV

ENSGT00700000104266_Linker_0_2 (158, 367)

SDLLKQQQANLTLQESMLEEQLL
AQQQREAAS--QESQKELKNMIGTLAKQLQEKTEAETELNRQYLTLQEALKRMENFS---
------------------------------------------------------------
--------------------------------------------GPCPQDWLWHEKNCYL
FSSG--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SYNWEKSKERCLSLDAQLLTINSTEDL-------------------DFIQQTI
S----HSNFPFWLGLS-QRKPN--YSWLWEDG----S---PLMPHLFR---------FQG
AVSQRYPSGTCAYIQRGNIF--------------AENCILVAY---SICQKKAELLT---
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSP-VPN--------TY--Q------------KC-------LS--S
NRCSGAWCLVMVISCIFCLGLLTTSI--FLTIKLLQVSTIVIQQQEKLIQQERALLNC--
--------T-------QWNRSHAL-----------------QMKHCQTFMQNFLSS-A--
------------------------------------------------------------
-----------------------------------------HNCNPCPDNWIQNGESCYY
VSEK---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

YWHTSQENCLKEDSRLLQIDSKEEM-------------------DFITGSL
RKI--ERGHKYWVGLS-QNGHS--ARWLWQDG----S---SLSPGLLPV-----------
-ERSQSTNQVCGYVKNHSLL--------------SSNCSSWKH---FICEKYALRPS-I-
--------------------------------------------------------

---------MPFSALLPEL--------AHSSQAAWGNLITSSLHPCRNVMQAKFSSTR--
-DMLDDDGDTTMSLHSRASAETR-------RP--------EP-------GHTEH-GTP--
---SSAWRPVGLTLLTLCLVLLIGLA--VLGLVFFQFYQLSNTQQDSISQKEE-------
---------------------------RLGNLSRQLQSLQAQNRKLAETLQHMAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GGHRCSPCPEKWKWHEDKCYQ
FYKE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SRSWQGCEHFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGRD--KAWLWMDG----S---PYSLELFDI--VIDVT----
----TPRNRDCVTILNGKAF--------------SKDCRELRR---CACERVAALVK-PE
RLH-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGTSTVTR-------RA--------EP-------RHSEN-GTP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNIQQDSITEKDE-------
---------------------------KLGNVSRQLQSLQTQNRKLIETLQQVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKNWQSCEYFCLADNATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACEKVAGRVV-PE
ELQ-----------------------------------------------------

---------------------------------------------------MEYHSGV--
-ENLDEDGYTQLNFHSQGITGR-------------------PVVLEKV------TCAT--
---SPRWRPIAVTLGILCLLMLVIAV--ILGTT---AFWRFN----------S-------
----------------------GSNPLKNDNFPSRNKE------NHSQPTQSSLED----
------------------------------------------------------------
---------HVAP-TKALTT---------------T-GA---FSSSCPPNWITHKNNCYL
FSTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

ASWNRSKRHCSQLHSNLLKIDTAEEL-------------------EFIVRQV
SSQ---PDNSFWIGLS-RHQTE--GPLLWEDG----S---VFSSNLFQ---------IRS
TDTQENSSHNCVWIHLSIIY--------------DQLCSVPSY---SICEKKMS------
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDIPTSE-----------SSQ------------NC-------PS--P
SKCSGTLCVVTMISCVVCVGLLATSI--FLGIKFFQVSSLVMEQQERLNQQNTTLLNL--
--------T-------QQQRKHTL-----------------E--YCQALLQRSLHP-GTD
ASTGPVLQTY-------------PQMVPQ-------------------------------
ILDSK---------ER------------------------GNDCSPCPHNWIQNGKSCYY
VFER---WG

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

TWNNSTKNCLKEGDGLLQIDSKEEM-------------------EFISHSM
GKL--KRGDEYWVGMF-QDGLS--GSWFWEDG----S---SPLSDLLPT-----------
-ERRPSASQICGYLKDHTLI--------------SDKCSSWKY---FICEKKAFGSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKQ---ALS---------------------SA------EP-A--
---SSWWRVAALVLLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLAEKENLSDTLHQL-AK----
------------------------------------------------------------
---------KFCQ-ELIRQS----------EIKTK--NTFEHKCSPCATKWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESREYCNEQNATLVKSASQSTL-------------------DYI----
AERI---TSVRWIGLS-RQNSK--KDWMWEDS----S---VLRKNS----ID-----L--
-SGNTEENMNCAYLHNGKIH--------------PASCKERHF---LICERNAGMTR-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MSEDVTYA-------TLMFQDSVSAGNNQDRNNLRKR--------G------YPAP--
---SSIRCQAALGLLTLCLMLLIGLV--TLGIMFLQMSSE----------INS-------
---DSDKLTQLQKITHQQQDNLSQRLSEYRNFPMEEEFLKSQISSLLNRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHKCNPCPKTWKWYQTGCYY
FAIN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWPNSRKNCMDKNSTLVKTDSLEEK-------------------DFL----
RSQPLPEFPFFWLGLSWDPSG---RSWLWEDS----S---RPSPSLFSANEY---AQI--
-----NESKGCAYFQNGNIY--------------ISRCSAEIS---WICEKTAALVK-IE
DLD-----------------------------------------------------

-------------------------------------------------VWIDFFTYS--
-SMSEEVTYA-------DLKFQNSSETEKVQE---IGK-----FGEKA------PPAP--
---SHVWRPAALFLTLLCLLMLIGLG--VLGSMFH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSRS--TSYPYWLGLS-PEKDY--SYATIMDN----I---INSSAW----VIRNAPDL-S
N-------MFCGYINRIYVH--------------YDYCTYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MNLETIFD-------DLKMKS----MKDQPDQ-------KSFGKKV---KGLRFLS--
---SPCWCPAAMTLGILCLGLLVTVI--MLKKQIFQISDFLEQYQANVTHQENILEGQLL
DYQQAKKDS--QNSQ---------------------------------------------
------------------------------------------------KELREIIDTLYQ
KLD--------------EGYKEKEELLQQNLDLQEALSRKENYSGPCPQDWIWHRESCYL
FSSG---LF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWESSRKNCSALGAQLLKIKNMNDL-------------------NFIHQMI
S----HSNLPFWMGLT-LRMPN--YSWMWEDG----S---PLRPHLFK---------LRG
AFAHMYPSGTCAYIQWGDIF--------------ADNCILVAA---HICQKAAYLL----
--------------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVRSNQDGNNLRKE--------G------HPAP--
---SSIWRGAALSLMTLCLLLVTGLV--TLGIMFLQMSND----------TNS-------
---DSEKLSQLQKFIHPQQNNLSEILNISWKDPTEE-SLQSQISALLERQKQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHT-------------------SDHKCNPCPKTWQWHGNSCYY
FTTH--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKSWSDSRKDCIGKSATLVKIDSIKER-------------------DFL----
RSQPSLTPSFFWLGLSRNSTG---KHWLWEDG----S---SPSPTLFSNQEH---ARF--
-----NGSRGCAYFERGNVY--------------ISRCSAEIS---WICEKTASLVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPPSE-----------SSQ------------KC-------LS--F
TRISGTSCTVMMISCIFCMGLLTTSI--FLGIK---------------------------
---------------------------------------------------------S--
------------------------------------------------------------
-----------------------------------------HNCSPCPYNWIQNGESCYH
VFEN---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QKIWHSSKEDCLKDGSSLLQIDSKEEM-------------------DFINSIL
QKV--KAGSEYWVELS-QDGLR--GQWLSQDG----S---SPSPELLQI-----------
-KRTQSISQVCRYIRDSSLF--------------STNCSYLKY---FICEKEALRSP-V-
--------------------------------------------------------

------------------------------------------------------------
------KTFD-------NLKMKP----VKDHPDQ-------KSSSKKA---KGLRFLS--
---SPWWCPVAMTLGILCLGLSVTMI--MLGMQLFQVSDLLRQYQANLTRQEHSLEGQIL
AQQQAEHAS--QKSQRELKEMIETLTRKLEEKSKREEELRQQNLDLQDALQSAVN-----
------------------------------------------------------------
------------------------------------------SSGPCPQDWIWHGDKCYL
FSSG---QFG

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WEKSQENCLSLDGQLLGINSTDDL-------------------DFIRRAT
S----HSSSPFWMGLS-RKKPS--HPWLWEDG----S---HLKPYLFR---------FQG
AVSQTYPSGTCAYIQRGSIF--------------AENCVLAAF---SICQKKANLWR-TQ
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DFKTKT----MKDQPVE-------KSNGQKA---KGLQCLS--
---SPWWCLAAVTLGILCLGSLVTIV--LLGIQLSQVSDLLKQQQANLTHQEDILEGQSL
AQRQTEEAS--KESQRELKEMIETLARKLDEKSKEQMELRHQNLNLQEALKRAANFS---
------------------------------------------------------------
--------------------------------------------VPCPQDWIWHGENCYL
FSSG---P

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

SDWEKSRENCLSLDAQLLKINSTGDL-------------------DFIRQAI
S----HSSYPFWTGLS-LRKPN--YIWLWEDG----S---PLVPHLFR---------LQG
AVSQRYPAGTCAYIQRGAVF--------------AENCILVAF---SMCQKAANLLT-AQ
--------------------------------------------------------

-------------------------------------------------MQAKYRSTS--
-DMWDDDCGTTLSLHSQVSTASR-------RP--------EP-------RPTEPRRTP--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 159)

SSAWRPAALTLLALCLVLLVGLA--ALGLVFFQYY

ENSGT00700000104266_Linker_0_2 (159, 367)

QLSDTQQDRLAEKEE-------
---------------------------RLGNLSRETQSLQARNRKLAETLLRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GGHRCSPCPEKWRWHEDRCYQ
FYTE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-GRSWQGCKSFCLSENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNSSG--EAWLWTDG----A---PFNFQLFEV--AIDVT----
----NLRSRDCVTILNGKAF--------------SKDCRELRR---CACERPAEVVR-PE
SCCRIPGAPDGSDS------------------------------------------

---------MQREGAGFIF--------D-----TNMGFILSIESPAGIRMQTKYSSDRDV
RDMLDDDEDTTMSLHSRASTITG-------QP--------EP-------RHTEL-STP--
---LSAWRPVALTLLTLCLVLLAGLA--ALGLVFFQFYQLSNIQQALITEKEV-------
---------------------------RLGNLSQQLQSLQLKNKKLAETLQRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGPRCSPCPEKWKWRGDKCYQ
FYRD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCNAENSTMLKINTQEIL-------------------DFSMLQS
YSEF---FYSYWTGLS-RNGSG--KAWLWMDG----T---PYSFELFEI--IIDAS----
----SLRNRDCVTILNGKAF--------------SKDCRELRR---CACERTAARVD-PE
KLL-----------------------------------------------------

------------------------------------------------------------
--MHQEEIYCSLQWDSPTTE-----------GSQ------------KC-------LS--P
SKCSGTWCVVTVASCVLCVGLLATSI--FLGIKFFQVSSLAMNQQERLIQQNRQLLNL--
--------T-------QWQRNYTL-----------------QMKNCQAFQQRCPRS----
------------------------------------------------------------
----------------------------------------GSNCSPCPHNWIQNGKSCYY
FFQI---WNM

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WNGSKENCLKEDASLLQIDSKEEM-------------------DFLIRSL
RKL--K-EVGYWVGVY-QDELS--GSWFWLDG----S---SPLSDFVPT-----------
-ERLLSDSQICGYLKDQTLF--------------SDNCSSWKY---FICEKNALGSC-I-
--------------------------------------------------------

---------------------------------------------------MEYYSNT--
-ENLDEDGYTQLDFNSRDNSRR-------------------PIVSKKG------TCAA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 153)

SPRWCVIAVILGILFLITLVIAV--VLGT

ENSGT00700000104266_Linker_0_2 (153, 367)

K-DEAVWRSY----------S-------
----------------------GSNPLEN-NFSSRSNQ------NQSQPTQSSLEE----
------------------------------------------------------------
---------SMSP-TKALTT---------------R-GV---FSSPCPPNWIIHEKSCYL
FRKS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-QDSWDKSKKQCSQQGSSLLKIDSSEEL-------------------EFIRKQV
SSQ---PDNSFWIGLS-RPQTE--GPWLWEDG----S---TFSSNLFQ---------IRS
TVNLESLSHNCVWIHLSIIY--------------NQLCNVHSY---SICEKTI-------
--------------------------------------------------------

------------------------------------------------------------
--MSHEVTYA-------TLTFQDSSRARNNQDRNNLKKR--------G------NPAP--
---SPAWRQVALSLLTLCLLLLIGLV--TLGVMLLQMSRE----------MNS-------
---DSEKLSQLPKVIHHQQDNLSQQLDNNRTFSMEKEFLKSQVSKLLKRQEQLAV-----
------------------------------------------------------------
---------QLCR-ELITHT-------------------SDHKCKPCPKAWQWHGNSCYH
FTVN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

DKTWSNSRKDCRERNSTLAKIDDLREK-------------------DFI----
KSQPLAMTSFFWLGLSWLPSG---RNWLWEDE----S---VPSPSLFSNKEL---DQI--
-----NGSKGCAYFQRGNIY--------------VSRCSAEIP---WICEKTATPVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQNSAETGNNRNQNNRRKR--------G------YPAP--
---SPIWRQASLSLLTLCLILLIGLV--TLGILYLQASNE----------INS-------
---DSEKLSRLQKTVHQKQDNSSQQLGNYGNFSMEEDFLKSQISNLLKKQGQMAI-----
------------------------------------------------------------
---------KLCQ-QLIIHN-------------------SDHECNPCPKMWQWYQNSCYY
FTTN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWINSRKDCMDKNSTLLKIDSLEEK-------------------DFL----
KSQPLPKLSFFWLGLSWDPFG---RSWLWEDG----S---TPSASIFSTKEL---TQF--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIS---WICEKTAALVK-TE
DLK-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRNGNNLRKG--------G------QPAP--
---SPMWRHTALGLLTLCLMLLIGLV--TLGIMFLQISNE----------VNS-------
---GSEILSQLQKTVDQQQDNLSQPLGNSNNLSMEEGFLKSQISSLLNRLEQMAV-----
------------------------------------------------------------
---------KLCQ-ELIVHT-------------------SDHRCNPCPKMWQWYQNSCYY
FATN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLRFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKRCAYFQKGNIH--------------ISRCSAEIF---WICEKTATPVK-ME
DLD-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKHKSPAPSS------------------------V------DPAS--
---SSWWRVMALILLILSTGMVVALV--ALGIMSVT------------------------
------------------QQ-------------N---NFQAEKENLSGTVQNL-AK----
------------------------------------------------------------
---------NFCQ-HIIQQL----------EENQK--RSADHKCSPCETNWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKSYCSNRNATLVKTASKGTL-------------------DYI----
KDRT---VLIRWVGLS-RQNAE--KVWMWDDG----S---VLSKNM----LE-----V--
-LEDGGENMDCAYFHKGEIH--------------PTFCKNRHY---LMCERKAGMTK-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLSFQDSVGAGNHQNRNNLRKK--------G------L-----
---SHTWRWAALSLLTLCLLLLTGLV--TLGIMFLQTSKE----------INS-------
---DSENLSQLQKTIHHQQDNLSQQLSNYRNFPTEEELLKSQISNLLKKQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELVIHT-------------------SDHKCNPCPKMWQWHQNSCYY
FATN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 461)

EEKTWSSSRRNCMDKNSTLVKIDSLEEK-------------------HFL----
KSQPLPKLSFFWLGLSWDPSG---RSWLWEDG----S---SPSPALFSAY----------
------------------------------------------------------------
--------------------------------------------------------

---------------------------------------------------MEYHPDL--
-DMVDEDGYTKLNFSTRGATRR-------------------TVSLEKG------T-----
SAVSPPWRLIAVLLGILCTVMLVIAV--ALGFL---SEYLSN----------S-------
----------------------GSSSLEKDNSLSRNKE------YQNQPTKSSLEE----
------------------------------------------------------------
---------NAAL-TKALKT---------------T-GV---FSSTCPPNWIAHEKSCYH
VIIS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QDSWHGSKRRCSQLGSHLIKIDTLKEF-------------------EFIVGEV
SSY---TTNSFWIGLS-RNQTE--APWLWEDGS-------TFS-NLFQ---------IRS
TATEESTTHNCVWIHMGNAY--------------DQSCNIFSF---TICEKL--------
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDEDTTMSLYSQVSATTR-------RP--------EP-------RCTGH-RAP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLLFFQYYQLSNTHQATVSHMEE-------
---------------------------RLRNISQQFQSLQVQNTKLVESLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCNPCPEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKNWEDCKYFCLSQNSTMLKIDTKEEL-------------------EFAMSQS
YSEF---FYFYWIGLF-RPGGG--KVWLWMDG----T---PYTSELFHV--MIDVT----
----SPRSRDCVAILNRMIF--------------SKDCQELKR---CVCERRAARGK-PE
SLRFLPETSDFKTSFSYHPRNTPAVG------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDNPASN-----------SSQ------------KC-------LS--S
TKISGTWRTLMVISCIFCVCLLTTSV--FLGIKLFQASTTIMKLQEKLIRQDRELWNF--
--------T-------QWNKTHAL-----------------QRKCCQP----SFSS-A--
------------------------------------------------------------
-----------------------------------------HNHSPCPHNWIQHGESCYY
VFEN---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWQYSQEDCLKEGSSLLQIDSKEEM-------------------DFISSSL
QKV--KASSEYWVGLS-QDGVS--GPWLWQDG----S---SPPPELLPI-----------
-KTAQSISQVCGYLRDNSLF--------------SASCSNWKY---FICEKEALRLC-V-
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------PPAP--
---SRVWRPAALFLTLLCLLLLIGLG--VLASMFH----------VT---LKI-------
---EMKKMNKLQNISEELQRNVSLQLMSNMNISN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------KLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--RSYDYWLGLS-PEEDS--THGMRVDN----I---INSSAW----VIRNAPDL-N
N-------MYCGYINRLYVQ--------------YYHCTYKQR---MICEKMANPVQ-LG
SIYFREA-------------------------------------------------

-------------------------------------------------MQPKYSRTR--
-DMLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMEE-------
---------------------------RLGNTSRELQSLQAQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNRA-------------------GAHRCSPCTDQWKWHGDKCYQ
FYKD---G

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

KSWEDCKYFCLSENCTMLKINKQEDL-------------------EFAKSQS
RSPF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPETLGKGD-------------------------------------------

------------------------------------------------------------
------MNCE-------DLKIKT----MKGQPDQ-------KVPCGKDRNCLGPNCLS--
---SPWWCPVTMTLGILCLGLLVAII--MQRMQLSQVSDLLKQQQANLTHQENIQEGQVL
AQHQAEEAS--QESQKELQEIINTLIEKLDEKSKKQLELQHQILNLQEALKRAANFSGTL
GSVLPHQFKLS-QWSISNC--SKQKILQLLA--CTNISVS---------------NSKYE
KLIKNNKKYVYCW-KMYQMTKKE--LQNFLLRHNSLIKFILHFLGPCPQDWFWHEENCYL
FSSS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-PYNWEKSQETCLSLDAHLLKINSTDDL-------------------EFIQKAS
A----HSNFPFWMGLS-FRKPK--NSWFWEDG----S---PWRSHLFR---------LQG
A-SKTYSSGTCAYIQRGIVY--------------AENCILVAF---SICQKKANLLT-TQ
--------------------------------------------------------

------------------------------------------------------MEYP--
-SDVDEDGYTKLNFHSRDATRR-------------------PVDSEKG------SPAS--
PVAGSPWKLIAVILGTLCLVILVVAV--VLGS----------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------L-GV---VPSTCPPDWIVHEKSCYL
LILS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWYGSKRRCSQLGSHLLKIDTLKEF-------------------DFIVGQM
SSY---PINSFWIGLS-RKQTE--ELWLWDDGS-------TFSYNLFQ---------IRS
TATQENTTHNCVWIHMGNAY--------------DQACNIPSF---SICEKLLSG-----
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSSQTENIQK---FDK-----FEKED------PPVP--
---SHVWRQGALALTLLCLLLLIGLG--VFGAIC--------------------------
----MEKLNKLQNFKEELQRNMSLQLMQNTNSSQ-------KIRNLSIKLEEIAT-----
------------------------------------------------------------
---------KLCR-ELYTKN-------------------KEHKCKPCPEEWMWHDDKCYL
L-HAYQR

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QETWQKSDEICSGYNASLLTIKSKSVL-------------------EFI----
KSLK---LNNYWLRLS-PRKDN--TKYGNLD-----T---IFPLNW----FTRNTSVIND
Q-------MYCGYVYYATFY--------------YIKCTETKN---IICEKLAQPVK-TE
SILMSEILDGRK--------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDFDGDTFMSEWSRTSSTTQ-------RP--------EA-------GHTGR-RPP--
---SSVWRPVALTLLTSCSVLLIGLI--ALGIVFFQFYQLSNTQRDSISHKEE-------
---------------------------RLGNLSRQLQSLQTKHRKLAETLQRVAE-----
------------------------------------------------------------
---------KLCR-EHYNKS-------------------GEHRCSPCPEEWKWHGDKCYR
FCKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCIAENATMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----A---PYSSELFEI--IIDFT----
----SLRSRDCVTILNGKAF--------------SKDCKELRR---CACERRAATVK-PE
SLH-----------------------------------------------------

----------------------------------------ML-SIQGLPRAMEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GSNSLENGYFPSRNKE------NHSQPTQSTLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GL---LSSPCPPNWIIYEKSCYL
FSLS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQVGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQASATTR-------HP--------EP-------WRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--ALGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNASQELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------EFAASQS
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFTSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCKELKR---CVCERRAGMVK-PE
SLHVPPETLGEGD-------------------------------------------

------------------------------------------------------------
--TSDQVTYA-------TLMFQDSTGARHNQNGENLRKR--------G------HPVA--
---SPIWRTVAVSLLTLCLILLMGLV--TLGIMFLQMYND----------INS-------
---DSENLNQLQKVIHQRQDNLSQQLKNSKKISTDD-DLQSQISKLLQKQGQMAT-----
------------------------------------------------------------
---------KLCK-ELLIHT-------------------SDHKCNPCPKSWQWHENSCYY
FTIN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWRDSRKDCADRNATMVKIDSIREK-------------------DFL----
QSQLLPTFSFFWLGLSWNQSD---RNWLWEDG----S---VLSPSLLSNKER---DQM--
-----TGSAGCADFERGNIY--------------ISHCSAEIS---WICEKTASLVK-TE
DLD-----------------------------------------------------

--------------------------------------------------PCALSGYP--
-SMSEEVTYA-------DLKFQNSSERENIQV---FYK-----LEEKA------PPAP--
---SYVWRQRALCLTLLCLLLLTALG--VLASMFY----------VT---LKI-------
---EMEKTNELQNVKEELQSNVSLHLMNITDSSQ-------KIRNLSITLQNIAT-----
------------------------------------------------------------
---------RLCY-ELYKKE-------------------PEHKCKPCPKNWRWHKDMCYG
LHNE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LQTWQKSEVICSGQNASLLTIKDKSVL-------------------EFI----
KSL---NLYDYWLGLS-PRKDY--IHSKTVDG----L---INSSDW----FIRNTDDS-N
K-------KFCGFIYGINVY--------------YNKCMDTKR---YICEKMADSVK-T-
--------------------------------------------------------

-------------------------------------------------MLAKYSSTR--
-DMLDADGDTTMSLHSQASATSQ-------RP--------EL-------GHTEH-QRP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDSILQKEE-------
---------------------------KLGNLSRQLQSLRSQNRKLAETLHHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWMDG----T---PYSSELFEL--MIDLT----
----SLRSRDCVTILNGKAF--------------SKDCRELRR---CACEKAAATVK-VQ
SLHEPLSRRWR---------------------------------------------

---------------------------------------------------MEYHSHV--
-ENLDEDGYTQLDFRTPGILKK-------------------AVGSEKG------SRSP--
---SPHWRPLAVTLGILCLVALVVAV--VLGFL---GEYGFN----------S-------
----------------------GKNPEEKENFPSRNKE------NH-KPTKSSLDE----
------------------------------------------------------------
----------MAP-SKASQT---------------T-GL---FSGPCPPNWIMHDKSCYL
FKMS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QNSWAGSKRHCSQLGSHLLKIDNPKEF-------------------EFIESQT
SSH---HINSFWIGLS-RKQNE--GPWLWEDG----S---LFTPNSFQ---------IRD
TASQESLLHNCVWIHGSQVY--------------NQVCNISSF---SICEKQL-------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKP---TLS---------------------SA------DS-A--
---SSWWRVMTLILLISSVGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLADKASLSATLQQL-AK----
------------------------------------------------------------
---------KVCQ-ELIKQS----------ELKTK--NAVEHKCSPCATKWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWDESKQFCTEQNATLVKAASQKTV-------------------EYI----
TNRI---TSARWIGLS-RQNSD--KDWMWEDS----S---IFPKNM----IG-----L--
-SGNTGENMNCAYLYNGKIH--------------PASCEDRNY---LMCERKAGLTR-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--C
NKCSGACCLVMVTSCIFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKGSHVL-----------------QMKFCQTFMQNSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WRI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPDLWPV-----------
-ERAQSTNQVCGYIKNGSLL--------------PSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

---------------------------------------------------IFLFLLS--
-SMSEEVTYA-------DLKFQDSNKRDNTVA---FEK-----LEIKA------CPAP--
---SRVWHLRV--LTFLCLLLLIGLG--VLGGMFY----------VT---FKQ-------
---HVEEVNKLQKVKDELQRNVSLQMMNNMSNTM-------VIRKLSRDLQEMAR-----
------------------------------------------------------------
---------KLCR-ELYKKD-------------------QEHKCQPCPKRWSWIDDKCYL
FSVD--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

TSETWQDSKKKCWNQNATLLTISSKRVL-------------------EFL----
KSQK--KINEVWLNLLLPEHRA--SSYPKRLD----S---ITSSDW----FINNADTLNE
K-------IYCGSSDGNYLY--------------FGGCRYKHH---FICEKMASPVK-I-
--------------------------------------------------------

---------------------------------------------------MEYHSHL--
-ENMDEDGYTQLNFNSKGNFRR-------------------PMDPEKG------QRTP--
---SPPWRLIAVAFGILCLVTLVIAT--VLGAL---GERS-S----------S-------
----------------------GRNPEEKDNFLSRNKE------NH-KPTKSSLDE----
------------------------------------------------------------
---------KVAP-SKAPKT---------------T-GF---FSGPCSPNWIMHQKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

ESWHTSKRRCSQLGSNLLKIDNANEL-------------------EFIESQV
SSH---PANSFWIGLS-RNQSE--GAWLWEDG----S---ILSPDLFQ---------IRN
TPTQENSLHNCVWIHLSEVY--------------DQICSTASF---SICEKQLQ------
--------------------------------------------------------

---------------------------------------------------MKYHSHI--
-ENLDEDGYTQLDFSTQDIHKR-------------------PRGSEKG------SQAP--
---SSPWRPIAVGLGILCFVVVVVAA--VLGAL---GG----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------FSQPCLPNWIMHGKSCYL
FSFS---G

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWYGSKRHCSQLGAHLLKIDNSKEF-------------------EFIESQT
SSH---RINAFWIGLS-RNQSE--GPWFWEDG----S---AFFPNSFQ---------VRN
TAPQESLLHNCVWIHGSEVY--------------NQICNTSSY---SICEKEL-------
--------------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFNSQSNTRI-------------------AVVSEKG------SCAA--
---SLPWRLIAVILGILCLVILVIAV--VLGTV---AIWRSN----------S-------
----------------------GSNTLENGYFPSRNKE------NHSQPTQASLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWMIYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLLKIDSSNEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATNENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
------MTCD-------DLKIKT----MKDQPDE-------KINGKKA---KGLHFFS--
---SPWWCLAAVTLGIFCLVSLVTIT--VLAMQLSQVSQLLKQQQTNLTHQESKLEGQIL
ARRQAEEAS--QESQKELKEMIETLARKLNEKSKEQMELHQQNLALQEALKRAGNFS---
------------------------------------------------------------
--------------------------------------------APCPQDWFWHEENCYL
FSSD---PF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQKNCLSLDAQLLKINSTADL-------------------DFIQKVI
S----HSSSAFWMGLS-KRKPN--NTWLWEDG----S---PLMPQLFR---------LQG
AVSQKYPSGTCAYIQRGAVF--------------GENCALVAF---SVCQKKANLLK-AY
--------------------------------------------------------

-------------------------------------------------MQPKYSSTR--
-DMLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMAE-------
---------------------------RLGNTSRELQSLQVQNRKLSGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GVHRCSPCTDQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWEDCKYFCLSENCTMLKINKQEDL-------------------DFAMFQS
RSPF---FYSYWTGLL-RPDSG--KAWMWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPETLGEGD-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------A

PF00059 // ENSGT00700000104266_Domain_2 (415, 531)

FIQRAA
S----HSSSPCWIGLS-PPEPS--HSWLWEDG----S---PLPALLFR---------LQG
AFSQKYPSGTCVYIQHGAFF--------------AENCILAAF---SICQRKAYSWG-TR
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPI

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQYNLSQQLGNSNNLSMEEDFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHI-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSNKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKMAAPVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRDGNNLRKR--------G------HPAP--
---SPI

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSKISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTKN--EEKTWANSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDS----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DSD-----------------------------------------------------

-----MKVHLFYSLNTNIVSHYCENVTNFSSFTNLLQTTRGVICSSLLCGLLSYQSTS--
-DMHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--C
NKCSGAWCLVMVISCIFCMGLLTASI--FLGIKLLQVSTTAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQNSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WRI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERAQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYVLRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MNLEMTFD-------DLKMKS----MMDQPDQ-------KSFGKKA---KGLRLLS--
---SPCWCPAAVTLGILSLGLLVSLV--LLREQLFQVSDLLKQYQANLTHQANILKGQLL
AQQQAEKHC--QNSQRELKNTINSLYQKVDEEAKEKMELHKQNLHLQEALERMENYSVFQ
VSDLLKQYQANLTHQANIL---KGQLLA--------QQQAEKHCQNSQRELKNTINSLYQ
KVD--------------EEAKEKMELHKQNLHLQEALERMENYSGPCPQDWIWHGENCYL
FSSG---MF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSSKNCSALGAQLLKINNKGDL-------------------DFIREAT
S----HSNLPFWMGLR-LQKPR--NSWLWEDG----S---PLRPHLFK---------LQG
AFPNMYSPDTCAYLQRGDVF--------------HENCILVAA---PICQKAADLLW-TQ
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSTKTANTKG---LDK-----FGKKA------PPAP--
---SRVWRQTTLTLSLLCLLLLVGLV--VLGITFY----------LT---LKI-------
---EMGKLNKLQNIEEELQRNVSVQLLNNQNSSE-------KIRNLSIALQNVAT-----
------------------------------------------------------------
---------RLCR-ELCRKD-------------------PEHKCKPCPESWIWHKDHCYL
LRDD---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESDRFCSALNASLLTMRNKSEL-------------------EFI----
RSK---ELFHYWLGLF-PRKDY--KLSEKIEN----L---VFSSAG----FKRNTGDL-K
Y-------MYCGYIYRTSVY--------------YIRCSEIKK---ILCQKMANPSLNIE
SILTSDFPDGGM--------------------------------------------

-------------------------------------------------MQAKYNSTL--
-DMLDDDGETTLSLRSQALTITP-------RP--------ES-------KNTGY-LAI--
---SPHWRPVALTLLTLCLLLLIGLG--VLGLEFFQLNQLSITQSHILNQKEE-------
---------------------------KLGNFSRQLHSLQAQNRKLTDTLQHLAK-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPKKWKWHKDSCFC
FSKE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

SNTWQGCEHFCTVENSTLLKIETQDIL-------------------EFVMPQS
YSQF---FYSYWTGLT-RNGSG--NPWLWLDG----S---LHSSDLFDI--VIDFS----
----SLKSWDCVTILNGRAF--------------AKDCKELRR---CACQRTAAMVM-PE
LLE-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDNPTPN-----------SCQ------------KC-------LP--S
TRCSGTWCLVMVISCIFCMGLLATSI--FLGIKLFQVTTIAMQQQEKLMQQHTALLNC--
--------T-------QWKRSHAH-----------------QMKHCQALRQSSFSR-A--
------------------------------------------------------------
-----------------------------------------NNCSPCPDNWIHNGESCYH
IFQI---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

VWHHSKENCLKEGSMLLQIDSKEEM-------------------DFIIGSL
RKA--KESNDYWVGLT-QDGLS--KPWLWQDG----S---TPSPGLLPT-----------
-DKSQSTNQFCGYLRNTALF--------------SANCSNWKY---FICEKYALRVS-I-
--------------------------------------------------------

------------------------------------------------------------
--MHAEEIYTSLQWDIPTSE-----------ASQ------------KC-------QS--P
SKCSGAWCVVTMISCVVCMGLLATSI--FLGIKFFQVSSLVLEQQERLIQQDTALVNL--
--------T-------QWQRKYTL-----------------E--YCQALLQRSLHS-GTD
ASTGPVLLTS-------------PQMVPQ-------------------------------
TLDSK---------ET------------------------GSDCSPCPHNWIQNGKSCYY
VFER---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

MWNISKKSCLKEGASLLQIDSKEEM-------------------EFIS-SI
GKL--KGGNKYWVGVF-QDGIS--GSWFWEDG----S---SPLSDLLPT-----------
-ERQRSAGQICGYLKDSTLI--------------SDKCDSWKH---FICEKKAFGSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDIPTSE-----------ASQ------------KC-------PS--P
SKCSGAWCVVTMISCVVCVGLLATSI--FLGIKFFQVSSLVLEQQERLKQQDTALVNL--
--------T-------QWQRKYTL-----------------E--YCQALLQRSVHS-GTD
ASTGPVLLTS-------------PQMVPQ-------------------------------
ALDSK---------ETANSPKTGPASPSPLPWFPRDTASQSSDCSPCPHNWIQNGKSCYY
VFER---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

RWNISKKSCLKEGDSLLQIESKEEM-------------------EFIS-SM
GKL--KGGNEYWVGAF-QDGLS--GSWFWEDG----S---SPLSDLLPT-----------
-ERHRSASQICGYLKDFTLI--------------SDKCNAWKY---FICEKKAFGSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKQ---ALS---------------------SA------EP-A--
---SSWWRVVALVLLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLAEKENLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIRQS----------EIKTK--STFEHKCSPCATKWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTEQNATLVKTASQSTL-------------------DYI----
AERI---TSVRWIGLS-RQNSK--KDWMWEDS----S---VLRKNG----IN-----L--
-SGNTEENMNCAYLHNGKIH--------------PASCKERHY---LICERNAGMTR-VD
QLL-----------------------------------------------------

-------------------------------------------------MQAKYSSSR--
-DMLDEDGDTTMSLYSQASTITR-------QL--------EP-------RQAEQ-RTP--
---SSAWRPVALTLLTLCLVLLLGLA--ALGFVFFQFYQLSSTQQDSISEKEE-------
---------------------------RLANLSQHLQSVQVRNRKLAETLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHKCNPCPEKWRWHGDQCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCTGENATMLKIDTQEVL-------------------EFAMPQS
YSEF---FYSYWIGLS-RNSSG--KAWLWMDG----A---PYSFELFEI--IIDVS----
----SLRSRDCVTILNGKAF--------------SKDCRELRR---CACQRMAARVE-PE
NLHSSP--------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVRGNQDGNNLRKE--------G------HPAQ--
---SSLWRVAALSLMTLCLVLVTGLV--TLATMFLQVSND----------VNS-------
---DSEKLSQLPEITHPQQDNLSEPPNSSRKSLTEE-SLQSQISALLERQEQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHA-------------------SDHKCNPCPKTWQWYGNSCYY
FSIN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKSWSDSRKDCTDKNATLVKIDSTEER-------------------DLL----
QSQLSLTFSFFWLGLSWNSSG---RNWLWEDG----S---FPPPTLFSDKEL---ASF--
-----NGSRECAYFEKGNIY--------------VSRCSAEIS---WICEKRASLVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------NLKIQDSDKKEETQK---SDK-----CGGKV------SSAA--
---SHSQQKTVLILILLCLLLLIGMG--VLGGIFY----------TT---LAT-------
---ETIKSNRLQSVKEELQENISLQLMHNLNNSK-------KIMNLSAMLQSIAT-----
------------------------------------------------------------
---------QLCR-ELYSKE-------------------PEHKCKPCPKGSEWYKDSCYS
QLNV---YA

PF00059 // ENSGT00700000104266_Domain_2 (370, 530)

TWQESVTACSARNASLLKVKNKDVL-------------------EFI----
KYKK---LRYFWLALL-PRKDR--TQYP-LSE----K---MFLSEE----SERSTNDIDK
--------KYCGYIDRVNVL--------------YTYCTDQYY---IMCEETASKVQ-VE
SVLNGLPEDST---------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGTSTVTR-------RA--------EP-------RHSEN-GTP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNIQQDSITEKDE-------
---------------------------KLGNMSRQLQSLQTQNRKLIETLQQVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWYGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKNWQGCEYFCLADNATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERIAGRVV-PG
ELQ-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKQ---ALS---------------------SA------EP-A--
---SSWWRVAALVLLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLAEKENLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIRQS----------EIKTK--STFEHKCSPCATKWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTEQNATLVKTASQSTL-------------------DYI----
AERI---TSVRWIGLS-RQNSK--KDWMWEDS----S---VLRKNG----IN-----L--
-SGNTEENMNCAYLHNGKIH--------------PASCKERHY---LICERNAGMTR-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MNLEMAFD-------D-KMKP----VNGQPDQ-------KSCGKKP---KGLHLLS--
---STWWCPAAVTLAILCLVLSVTLI--VQQTQLLQVSDLLKQYQANLTQQDHILEGQMS
AQKKAENAS--QESKRELKEQIDTLTWKLNEKSKEQEKLLQQNQNLQEALQRAVNASEES
KWELKEQI-DILNWKLNGISKEQKELLQQNQNLQEALQKAEKYSEESQREL---------
----KEQIDTLSW-KLNEKSKEQEELLQQNQNLQEALQRAANSSGPCPQDWIWHKENCYL
FHGP----F

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSRENCLSLDAQLLQISTTDDL-------------------NFVLQAT
S----HSTSPFWMGLH-RKNPN--HPWLWENG----S---PLSFQFFR---------TRG
VSLQMYSSGTCAYIQGGVVF--------------AENCILTAF---SICQKKANLLL-TQ
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIKT----MKDHPDE-------KSNGKKA---KGLPFLY--
---SPWWCLVAVTLGVLCLGSVVIII--KLGVELSQVSDLLTQQQANLTHQKNKLEGQIS
ARQQAEEAS--QESQKELKEIIETLAQKLNEKSKEQMELHQQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHQENCYL
FSSG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LDWKKSQENCLSLDAKLLKINSTADL-------------------DFIVQAV
S----HSSFPFWIGLS-RRNPR--YPWLWEDG----S---PLMPYLFR---------LRG
AVSQTYSLGSCAYIQQGTVF--------------AENCALVAF---RICQKKANLLR-AQ
--------------------------------------------------------

------------------------------------------------------------
--MHEEEVYTALQWDSPTPH-----------SSQ------------KC-------LS--S
TKISGSWCTLMVISCIFCIGLLSTSI--FLGIKLFQATTTIMKQKEKLIQQDRELSNC--
--------T-------QWEKKHVL-----------------QKKYCQNLPQSFNSS-A--
------------------------------------------------------------
-----------------------------------------RNCGPCPHNWIQNGGSCYY
VFET---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHSGKENCLEEGSRLLQIDSKEEM-------------------DFVSRSL
QKV--KANTDYWVGAS-WDGPP--GPWLWQDG----S---APPPDLLPI-----------
-TRPQSINQVCAYLRNNSLF--------------SASCTSWKY---FICEKDARSSI---
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------QVSIMAMEQQEKLSQQDRALLNL--
--------T-------RWKSNPLL-----------------QRQHCQALIQNCLNS-V--
------------------------------------------------------------
---------------------------------------KVEKCSACPENWIKNGESCYY
VFTN---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

KTWLASQEYCWKTGSSLLHIDNKEEM-------------------DFITS--
-KI--ERSMGYWVGLS-QDEVR--RTWLWEDG----S---PPSSDLLPR-----------
-HQPQSTNQVCGYLKSNSLF--------------SSNCSSWKY---LICERRA-------
--------------------------------------------------------

---------------------------------------------------MEYRSEV--
-ENLDEDGYTRLDFSSQGVTGR-------------------HAVSEKG------TCAT--
---SPYWRPIAVTLGILCLVILVTAV--VLGTT---AIWRPN----------S-------
----------------------ESNPLKNDNFPSRNKE------NYSQPTQSSLED----
------------------------------------------------------------
---------SVAP-TKALTT---------------T-GV---FSNSCPPNWIIHENNCYL
FRTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

ASWNSSKKQCSQLHSNLLKIDSEKEL-------------------EFIMKQA
SSQ---PDNSFWIGLS-RHHTE--GPWLWEDG----S---RFSSDLFQ---------IRS
TEIQENSSHDCVWIHLSIIY--------------DQLCSLPSY---SICEKKLSIK----
--------------------------------------------------------

------------------------------------------------------------
--MQEEETYTSLRWDSPTPS-----------FYQ------------KH-------LS--S
TKYSGAWCLVTVITCILCVGSIATSV--FLGLKLFQVSTIAMKQREKLILQDRALLNF--
--------T-------QWERNHNL-----------------QMKYCQTLMQNSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPDNWIQNGESCYH
VFEN---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KIWHTSKEDCLKEGSNLLQIDSKEEM-------------------DFITGSL
KKV--KSGFDYWVGLS-QDGLS--KPWLWQDG----S---SPSPDLSPV-----------
-QTLQSTNQLCGYLKDKFLS--------------SANCSIWKY---FICEKYALRSS-N-
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDPDWDTTMSLHSYTSATTR-------RP--------EP-------GHSEH-PPS--
---SSAWRPVALTLLTLILVLLIGLA--VLGLVFFQFYQLSNTQQDSISQKEE-------
---------------------------RLGNLSRQLQSLQARNRKLTEMLQHVAE-----
------------------------------------------------------------
---------KLCW-ELYNKT-------------------GEHRCSPCPDTWKWHGDKCYQ
FSKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYLCIAANSTMLKINTAEVL-------------------EFVMPQS
FSEF---FYSYWTGLS-RNGSG--KAWLWLDG----V---PHSSELFEI--IIDLN----
----SLRNRDCVTILNGKAF--------------SKDCKELRR---CACERMATVVE-LE
RLIVAESLGAVDS-------------------------------------------

---------------------------------------------------MDYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCVA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GRNSLENGYFPSRNKE------NHSQPTQSPLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSPS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDASKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

MCPNSHGPTLPEREDHRLT------------DTNIYKSGHHN-FAKSLNPELTYSPKE--
-AMLDEDGYITLNIKTRKSALTS------------------------V------DSDN--
---SSLWRVMALILLILCVGLIVGLV--TLGIMSVT------------------------
------------------EQ-------------N---YQQVENKNVSGTLNQL-AK----
------------------------------------------------------------
---------QFCQ-YLIKQS----------EQKSN----VRHKCSPCDRNWRYYGDSCYG
FFKH---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

NLTWEESKQYCINVNATLLKITSQKVL-------------------KYI----
KSRT---GFIRWVGLS-RKNPN--EIWMWEDG----S---VPSKDV----FE-----L--
-SGNERENMNCAYFYNGKIY--------------PTVCKNKHY---LICERKAGMVN-VD
ALL-----------------------------------------------------

------------------------------------------------------------
---KKDTSWQ-------AFLLNLSPRVEGENTNVNMRR-----EGVPE------HPAP--
---SPARRCSVLGLLTLCLLLLIGLA--SLGILYLCCS----EQVRKTNT----------
--------E----QLNGLEKNLSLQLETIANISK---EKEMIQSNLTDALQEMAT-----
------------------------------------------------------------
---------KLCR-ELSSSK------------------PDNHACKPCPKDWDWHENSCYS
LERK---

PF00059 // ENSGT00700000104266_Domain_2 (368, 463)

QQTWEDSSKACNNRNSSLVKIDSKEEW-------------------CMLSSFI
SLQY---NQYIWVGLS-RNSSS--SQWKWEDG----S---ALSPDL--------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MEDEDGYMMLHIKSSRIHYSSKS---------------P-----SG------PRTP--
---SSLWRPVALALLVLCLLSLSGVV--TLGTMIIR------------------------
------------------QP-------------N---HVAIQDGNVSETLQQL-AR----
------------------------------------------------------------
---------RLCQ-ELVSKT----------KDALV--PSPGHKCNPCSS-LKYHQGNCYL
LSHR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

RTWEDSRTYCASKNYVMLKVDNQEEL-------------------AYI----
NRNT---NKIRWIGLS-RRAID--SPWMWEDG----S---VLATDL----FQ-----I--
-SGDGEANRHCAFFHNGKIQ--------------AADCQESYP---TLCESVGGNIK-ID
LLL-----------------------------------------------------

------------------------------------------------------------
--MSEEVIYA-------HLKFPESRKTENIQE---LDR-----FEIKA------PPVS--
---SHVWRQIALTLTFLCLLLLIGLG--PLGSIFY----------TT---LKR-------
---ETERLNTLQNVKEELQGNISLLLMTNLNKSE-------NIRNLSITVQNLAT-----
------------------------------------------------------------
---------KLCR-ELNRKE-------------------PGHKCKPCPNHWLWYKNNCYL
FSET---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

RQTWQDSATSCSSQNASLLQIKEKSTL-------------------EFV----
KSQK---LYYYWLGLS-PRQDD--KNSG---E----N---IISSAR----LKRYMNDINK
--------MFCGYIYATNIF--------------YVPCTERHL---LACEKKANPVK-AE
SVLMSEDPDREM--------------------------------------------

----------------------------------------------------MEYPDL--
-ENLDEDGYTQLRFSSRNNTRI-------------------SVVSEKG------SCAS--
---SLPWRLIAVILGILCLVILVTAV--VL---GTTATWRSN----------S-------
----------------------GSNPLKNGNFPSRNKE------NHSQPPQSSLEE----
------------------------------------------------------------
---------SVTP-TKAIKT---------------T-GD---LSSPCPSNWIMYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLDSNLLKIDSSKEL-------------------GFILKQV
SSQ---PDNSFWIGLS-RTQTE--GPWLWEDG----S---TFSSNLFQ---------IRT
TATQENSSSNCVWIHMSIVY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKSRKPPLSS------------------------A------DPTS--
---SPWWRVMALVLMILSVGMVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLQAEKENLSGTLQQL-AK----
------------------------------------------------------------
---------NFCQ-NLIKQL----------EQKQK--GSFYHKCSPCDTKWRYYGNSCYG
FFRQ---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

NLTWEESKQYCMDMNATLVKIASQNIL-------------------EYI----
KTRT---VLIRWVGLS-NQNSN--KVWMWEDG----S---IFSKNM----LD-----L--
-SGDETENMNCAYFHNGKIR--------------PALCKDRHY---LMCEKKAGLAK-VE
QLL-----------------------------------------------------

---------------------------------------------------MEYHSNT--
-DNLDEEGYTRLDFHSRGISQK-------------------PIISEKG------KCAS--
---SSRWCFIAVTLGILFLITLGIAV--VLGIL---AIWSSN----------S-------
----------------------GRNPLENTSFPTRRNP------SQSQPTKSSLEE----
------------------------------------------------------------
---------SVTS-TKSLRT---------------R-G----RADSCPPRWILYEKSCYL
FRLS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 464)

-LDSWDMSKEKCSLEHSSLLKIDDLREL-------------------DFITSQT
SLQ---PYHSFWIGLS-RPQAE--RGWLWEDG----S---AFSN----------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLTLQDSTGARNNRHANNLREQ------RXX------XXXX--
---XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX----------XXX-------
---X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQLA-----
------------------------------------------------------------
---------ILCE-ELILHT-------------------SDHRCNPCPETWQWHQDSCYY
FMAN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWTDSRKDCMDKNSTLAKIDSWEEK-------------------NYL----
KSHPLPTSSFFWLGLSWDHSG---RNWLWEDG----S---IPSPSLFNTKEL---AQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIS---WICEKTAAPVK-VD
NLD-----------------------------------------------------

------------------------------------------------------------
------MNCD-------DLKVKT----MKDQPEQ-------KLNAR---KARGPPFLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 173)

SPWWCLTTVTLGILCLGLLVTLI--IQKMQLSQVSDLLKQQQENITHQE

ENSGT00700000104266_Linker_0_2 (173, 367)

NILEGQML
AQQQAEEAS--QESQKELKDIIKVLADKLDEKSMKLTEVQNLNLNLQEALKRAA------
------------------------------------------------------------
-----------------------------------------NFSGPCPEYWLWHGENCYL
LSSS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-TFNWEKSKENCLSLNAHLLKINNTSDL-------------------EFIQKAS
A----HSSFPFWMGLS-HKKPS--NSWSWEDG----S---PWMPGVFR---------LQG
AVSKTYSAGTCAYIQRGIVY--------------ADNCILVAF---SVCQKKANLLR-VL
S-------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKMKS----MMDQPDQ-------KSFGKKA---KGLRLLS--
---SPCWCPAAVTLGILSLGLLVSLV--LLREQLFQVSDLLKQYQANLTHQANILKGQLL
AQQQAEKHC--QNSQ---------------------------------------------
------------------------------------------------RELKNTINSLYQ
KVD--------------EEAKEKMELHKQNLHLQEALERMENYSGPCPQDWIWHGENCYL
FSSG---MF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSSKNCSALGAQLLKINNKGDL-------------------DFIREAT
S----HSNLPFWMGLR-LQKPR--NSWLWEDG----S---PLRPHLFK---------LQG
AFPNMYSPDTCAYLQRGDVF--------------HENCILVAA---PICQKAADLLW-TQ
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDNQTSH-----------SSQ------------KC-------LS--S
TKISGIWCTLMVISCIFCVGLLTTSI--FLGIKVFQATTTIMKQEEKLIQRDRELLNC--
--------T-------QWEKKYTL-----------------QRKYYQTLLQNVFSS-A--
------------------------------------------------------------
-----------------------------------------HNCGPCPQNWIQNGKSCYH
VFKI---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KTWDSGKENCLKEGSRLLQIDSKEEM-------------------DFVSGSL
QKV--KASYEYWVGAS-QDGPH--GPWLWQDG----S---TPPPDLFPI-----------
-SRPPSVSQVCRYLRDNSLF--------------SANCTNWKY---FICEKDALRAS-I-
--------------------------------------------------------

---------------------------------------------------MKYHSHI--
-ENLDEDGYTQLDFSTQDIHKR-------------------PGGSEKG------SRAP--
---SSPWRPIAVGLGILCFVVVVVAA--VLGAL---GEYGHN----------S-------
----------------------GRNPEEKDNFPSRNKE------NH-KPTESSLDE----
------------------------------------------------------------
---------KVAP-SKASQT---------------T-GV---FSQPCLPNWIMHGKSCYL
FSFS---G

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWYGSKRHCSQLGAHLLKIDNSKEF-------------------EFIESQT
SSH---RINAFWIGLS-RNQSE--GPWFWEDG----S---AFFPNSFQ---------VRN
TAPQESLLHNCVWIHGSEVY--------------NQICNTSSY---SICEKEL-------
--------------------------------------------------------

------------------------------------------------------------
------MTFA-------DLKSQS----MKGQLDQ-------KPNGERD---KGLRFLS--
---

PF08391 // ENSGT00700000104266_Domain_2 (124, 361)

SRRWYPAVMALGILCLGLLVTVI--LLIIQLSQVSDL-KQQQANLTHQEDILKGQIS
AQPQTEKSS--QESQGELKEMIETLAHKLDEKSKKLMELHHQNLNLQEALKKAAN-----
------------------------------------------------------------
------------------------------------------YSGPCPQDWLWHEENCYQ
FSSG---PFNWEKSRENCLSLDAHMLKINSSDDL-------------------EFIQQAI
V----HSSFPFWMGLS-LKKPN--YSWLWEDG----S---PLMPHLFR---------LQG
AAFQMYSSGTCAYIQRGAVF--------------AENCILTAF---SICQKKANLLR-VQ
--------------------------------------------------------

-----------------------------------------------------FFTYL--
-SMSEEVTYA-------DLKFQNSTETENIRD---IDK-----LGGKA------APAP--
---SRVWRPAALFLTLLCLLLLIALG--VLGSTFY----------IT---LKI-------
---EMEKVNELQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTTAT-----
------------------------------------------------------------
---------KLCR-ELYREK-------------------KEHNCKPCPERWVWHEDSCYF
LSDD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKTWQESRMACAAQNASLLKINSKSAL-------------------EFI----
KSPN--KLYGYWLGLS-PEKDY--TNGKSVEN----I---INSSDW----VITNASDL-T
N-------MYCGYIGGLYVN--------------YYDCTYEQR---RICEKMANPVQ-LG
FIHFREASGIN---------------------------------------------

------------------------------------------------------------
--MHEEEIYCSLQWDSPPEE-----------GSQ------------KC-------LS--P
CKCSGTWCVVTVISCVFCVGLLATSI--FLGIKFFQVSSLAMNQQERLIQQDKQLLNL--
--------T-------QWQRNYTL-----------------QMKNCQALQQRSPRS----
------------------------------------------------------------
----------------------------------------GSNCSPCPHNWIQNGRSCYY
FFQI---WEI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WNRSKENCLKEGASLLQIDSKEEM-------------------DFLIQSL
WKF--K--DGYWVGVY-HDEPS--RSWFWLDG----S---SPLSDLLPT-----------
-ERQLPSSQICGYLKDQSLF--------------SDNCSSWKY---FICEKNALGSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKGRKPALTS------------------------V------DSAS--
---SPLWRVMALILLTLCVGLVIGLV--ALWMMSAT------------------------
------------------ER-------------N---YLQVENKNFSGTLHRL-AQ----
------------------------------------------------------------
---------QFCQ-YIIKQS----------EQKS------GHKCSPCDRNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCVNVNATLLKITSQKVL-------------------EYM----
KSRT---GFIRWVGLS-RKNTN--EVWRWEDG----S---VPSKDV----FE-----L--
-SGNGGDNMNCAYFYNGKIY--------------PTFCNDKHY---LMCERKAGMTK-VD
TLL-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRDGNNLRKR--------G------HPAP--
---SPI

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWANSRKDCIDKNSTLVKTDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISHCSTEIF---WICEKTAAPVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNVKTRKPVLSS------------------------V------DSAS--
---SSWWPVIALILLILCMGMVVGLT--ALGIMSVT------------------------
------------------QQ-------------N---YLQVENENLSGMLHQL-AK----
------------------------------------------------------------
---------RFCQ-YLIKQS----------EQKNN--F-ESHKCSPCDTNWRYYGDSCYG
FFKR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQFCTGMNATLLKIADQNIL-------------------EYI----
KTRT---SLIRWVGLS-RQNSN--EVWMWEDG----S---VLSKNM----FE-----F--
-SGDGRENMNCAYFYNGKIH--------------PTSCKDKHF---LMCERKAGMTK-VD
QLL-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------FQVSTLAMKQQEKLMQQDRALLNF--
--------T-------QWKRNPVL-----------------QMNYCQTLMQNSFS-----
------------------------------------------------------------
---------------------------------------SACNCSPCPDNWIHNGESCYY
VFEQ---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWHTSKEKCSKAGSTLLQIGSKEEM-------------------DFITGGL
KKI--KGSHPYWVGLS-QGGPS--SPSLWQDG----S---APSLDLLQR-----------
-ERFQSTDKVCGYLKDNSLL--------------SANCSSWKY---FICEKYALRSS-T-
--------------------------------------------------------

------------------------------------------------------------
--MNLETTCD-------DLKINT----MKDQPDQ-------KLNGEQPKGP---RIL---
---SRFWRPAAAILAIICLALLITVL--LMAVQLSQVSALIRQQRANLTHQEHRLEGQIL
AQRQVEEAS--QESQKELKEMIELLAQKLEVNSEKLMELHHLNLNLQEALKRAANFT---
------------------------------------------------------------
-------------------------------------------

PF05473 // ENSGT00700000104266_Domain_2 (344, 533)

-GPCPQDWIWHEENCYL
FASG---PFNWEKSQEDCLSLDAQLLKINNSADL-------------------EFIRQAT
A----HSSFPFWMGLS-LRKSS--HTWLWEDN----S---SWNPRLFK---------LQG
AVSQLYPSGTCAYIQRGSAF--------------AENCILVAF---GICQKKANLLR-PL
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTVSLYSGASTVTR-------RA--------EP-------RHSEN-ETP--
---SSVWRPVALTLLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDTITEKDE-------
---------------------------RLGNISRQLQSLQIQNRKLIETLQQVAV-----
------------------------------------------------------------
---------KLCR-ELYNRS-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCLAENATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---SYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERTAGRVV-PE
VLQ-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGTSTVTR-------RA--------EP-------RHSEN-GTP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNTQQDSITEKDE-------
---------------------------RLGNMSRQLQSLQTQNRKLTETLQQVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWHGNKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKTWQSCEYFCLADNATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRSRDCMTIFNGKAY--------------SKDCKELRR---CACERVAGRVV-PE
ELQ-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--C
NKCSGAWCLVMVISCIFCMGLLTASI--FLGIKLLQVSTTAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQNSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WRI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERAQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYVLRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-D----------TYQ------------KC-------LS--S
NKCSGACCLVMVISCVFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSCAL-----------------QMKYCQAFMQNSLSS-A--
------------------------------------------------------------
-----------------------------------------HNSSPCPNNWIQNRESCYY
VSEI---WSI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--KGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPA-----------
-ERSQSANQVCGYVKSNSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

---------------------------------------------------MKYHSHI--
-ENLDEDGYTQLDFSTRDIHKR-------------------PMISDKG------SRAP--
---SSPWRPIAVGLGILCFVAVVVAA--VLGAL---GEYEHN----------S-------
----------------------GRNPEEKDNFLSRNKE------NH-KPTESSLDE----
------------------------------------------------------------
---------KVAPPSKASQT---------------T-GV---FSRPCLPNWIMHAKSCYL
FSFS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWYGSKRHCSQLGAHLLKIDDSKEF-------------------EFIESQT
SSH---HINSFWIGLS-RNQSE--GPWFWEDG----S---AFSPNSFQ---------VRN
TAPQESLLHNCVWIHGSEVY--------------NQICNTSSY---SICEKEL-------
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLGDDGDTTMSLHSQASATTR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNMSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------DFALSQS
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFASELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CVCERRAGMVK-TE
SLHFPPETLGEGDWFS----LCNYK-------------------------------

------------------------------------------------------------
--MQEEGTYNSLQWDNPTPS-----------PYQ------------KH-------LS--S
TKCSGTWCLLVVISCIFCVGSVTTSV--FLGIKLFQVSTIAMKQQEKLIHQERTMWNF--
--------T-------RWQKNHNL-----------------QMKYCQTLMQNSFVS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNGGSCYH
VFEN---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSKEDCLKEGSNLLQIDSKEEM-------------------DFITGSL
RKI--KSGYDYWVGLS-QDGLS--RSWLWQDG----S---APPPDLSPV-----------
-KTLQSTNQLCGYLKDKSLS--------------SANCSIWKY---FICEKYAL------
--------------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------NLKFQDSDKKENLQT---SDK-----CGGKV------PSAP--
---SYSQHKAVLILTVLCLLLLIGLG--VLGGLFR----------TT---LGT-------
---EMIKSNQLQNIREELQRNVSLQLMHNMNSSK-------RIRKLSAMLQKTAT-----
------------------------------------------------------------
---------QLCR-ELCKNK-------------------PEHKCKPCPKGSQWFEDSCYS
KLGM---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

SETWQVSEMLCSSRNGSLLKIKNRNVL-------------------EFI----
KSKK---LKGYWLGLM-PRTKK--PPYEELNE----N---MFLSAG----FEGSTYDLSN
--------MYCGYINGGYVY--------------YSSCTSENY---VMCVETARTVQ-VE
SVLDDLPEGRN---------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTSISLYSGASTVTR-------RA--------DP-------RHSEN-ETP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNIQQDSIAEKDE-------
---------------------------RLGNVSRQLQSLQMQNRRLIETLQHVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPETWKWHKDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKNWQGCEYFCLAENATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAF--------------SKDCKELRR---CACERMAGRVV-PE
VLQ-----------------------------------------------------

------------------------------------------------------------
--MQEEETYTSLQWDNPTPN-----------PYQ------------KH-------LS--S
TKNSGTWCLVTVVLCIFCIGSLATSI--FLGVKLFQVSTTAMKQQQKLIQQDRALLNI--
--------T-------QWKRNHGL-----------------QMKYCQMLMQKSFS-----
------------------------------------------------------------
---------------------------------------SAHNCSPCPDNWIRNGESCYR
VFES--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WTIWRTSREDCLKQGSKLLQIDSKEEM-------------------DFITGSL
RKI--KRDYDYWVGLS-QDGSS--QPWLWQDG----S---SPSPDL-SI-----------
-QGPQSTIQVCGYLRKNSLS---------------PDCSTWKY---FICEKYALRSS-T-
--------------------------------------------------------

------------------------------------------------------------
--MSHEMTDA-------TLTFEDSSGTRNNQDKNNLKNR--------G------NSVP--
---SPVWRQVALGLLTLCLVLLLGLV--VLGIMFLQMSSE----------MNS-------
---DSEKSSQLPEVIHHQQNNLSQQLGNYKIIPREMEFLNSQVSNLLKRQEQMAI-----
------------------------------------------------------------
---------RLCK-ELIIHT-------------------SDHKCNPCPKTWQWYQNSCYY
FTIN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

DKTWSNSRNDCRDKNSTLVKIDNLEEK-------------------DFL----
TSQPLSTLSYFWLGLSWHPSD---RNWLWEDE----S---IPSPSLFSSKEL---AQI--
-----NGSKGCAYFQRGNIY--------------VSRCSAEIS---WICEKTAALVK-AE
DLD-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYCSLQWDSPPEE-----------GSQ------------KC-------LS--P
CKCSGTWCVVTVISCVFCVGLLATSI--FLGIKFFQVSSLAMNQQERLIQQDKQLLNL--
--------T-------QWQRNYTL-----------------QMKNCQALQQRSPRS----
------------------------------------------------------------
----------------------------------------GSNCSPCPHNWIQNGRSCYY
FFQI---WEI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WNRSKENCLKEGASLLQIDSKEEM-------------------DFLIQSL
WKF--K--DGYWVGVY-HDEPS--RSWFWLDG----S---SPLSDLLPT-----------
-ERQLPSSQICGYLKDQSLF--------------SDNCSSWKY---FICEKNALGSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPALIS------------------------V------GPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QR-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVVKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTDMNATLLKIDNRNIV-------------------EYI----
TART---RLIRWVGLS-RQKSN--EVWKWEDG----S---VISENM----FE-----F--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
------MIFD-------DLKSTT----MKDQPDQ-------KPNGEKA---KGLYFLS--
---SRWWCPAAVLLGVLCLGLLVTLI--MLIMQVSQVSGLLKQHQANLTHQEIILEGQIL
AQQQAEKAS--QESEKELKEMIKNLTQKLDEKSKKQMELHHQNLNLQEALREAAN-----
------------------------------------------------------------
------------------------------------------FSAPCPQDWLWHEANCYL
YSSG---PF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQNHCLSLDAHMLKINSTDDL-------------------EFIQRAS
A----HSSFPFWMGLS-LRKPS--SSWLWEDG----S---PLMPHLFR---------FQG
SLSQRYPSGTCAYIQRGAVF--------------ADNCILTAF---TICQKKATLVR-AR
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS---
SKCSGACCLVMVISCTFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHAL-----------------QMKYCQTFMQNSLSS-A--
------------------------------------------------------------
-----------------------------------------YNSSPCPNNWIQNRESCYY
VSEI---WSI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--QGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERSPSTNQVCGYMKNNSLL--------------SSNCSTWKY---FICEKYALRST-A-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKP---ALT---------------------SV------DT-A--
---SSSWRVMALILLVLSMGLFVGLV--ALGIMYVT------------------------
------------------QQ-------------N---YLLAEKKNLSETLQQL-TN----
------------------------------------------------------------
---------KACQ-DLIKLS----------ELKTK--RSFEHTCSPCETKWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCAEQNATLVKTASQRTV-------------------EYI----
TDRT---SSIRWIGLS-SQNAN--KLWTWEDG----S---VLSKNM----ID-----L--
-SGNTRENKNCAFLHNGKIH--------------STSCKDRHY---LMCERKAGLAK-LD
QLL-----------------------------------------------------

-------------------------------------------------MWTDFFTYS--
-SMSEEVTYA-------DLQFQNSSEKEKIPE---IGK-----FGEKA------PPAP--
---SCVWRPAALFLTLLCLLLLIGLG--VLASMFH----------VT---LKI-------
---EMKKMNKLQNISEELQRNVSLQLMSNMNISN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------KLCR-ELYSKE-------------------QEHECKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

HTWQESKMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--RSYDYWLGLS-PEEDS--THGMRVDN----I---INSSAW----VIRNAPDL-N
N-------MYCGYINRLYVQ--------------YYHCTYKQR---MICEKMANPVQ-LG
SIYFREA-------------------------------------------------

-------------------------------------------------MQPKYSSTR--
-DMLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMAE-------
---------------------------RLGNTSRELQSLQVQNRKLSGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GVHRCSPCTDQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWEDCKYFCLSENCTMLKINKQEDL-------------------DFAIFQS
HSPF---FYSYWTGLL-RPDSG--KAWMWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPETLGEGD-------------------------------------------

-----MKVHLFYSLNTNIVSHYCENVTNFSSFTNLLQTTRGVICSSLLCGLLSYQSTS--
-DMHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--S
NKCSGAWCLVTVISCIFCMGLLTASV--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSQENCLKEGSTLLQIESEEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-EISQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------HLKLRDSVKKENMQK---SEK-----HRGEV------PSAP--
---SCSQHKTVLILILLCLLMLVGLG--VLGGLFH----------TT---LET-------
---EIIKSNELQGIKEELQRNISLQLMLNHNSSK-------IIGNLSAMLQKTAT-----
------------------------------------------------------------
---------QLCR-ELYKKE-------------------PEHKCKPCPKGSKWYKDSCYF
KLGG---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

RTWQKSEIQCSVQNASLLKIKNKSVL-------------------EFV----
KSER---LNNYWLGLS-PRKDQ--AKSEKLTE----T---IFLSAG----FEGSMPDLSK
--------MYCGHIQGMYVY--------------YSPCIWEKN---VMCEGTASNVQ-VE
SVLNDLPEESL---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------MLLIGLV--TLGIMFLQTSNE----------INS-------
---DSEKLSQLQKIIHQQQDNLSEQLNSYRNIPTQEEFLKSQISSLLKRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHKCNPCPKMWQWYQNSCYY
FATN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

ERTWTNSRKNCMDRNSTLVKIDSLEEK-------------------DFL----
KSQPLPTFSFFWLGLSWDPSR---RSWVWEDG----S---GPSPSLFSTKEY---AQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIS---WICEKMAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSHEVTDM-------TLTFQDSSGASNNRDRNNLKTR--------G------NSAP--
---CPAWRQAALGLLTLCLALLIGLV--TLGMMFLRTSSE----------MNS-------
---DSKKLSQLPKVVHPQQDNLSQQLCNYQVIPREMEFLKSQVANLLKRQEKMAI-----
------------------------------------------------------------
---------KLCK-ELIIHD-------------------SDHRCNPCPKTWQWHQNSCYY
LTMK--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWSNSRNDCRDRNSTLVKIDDLEEK-------------------HFL----
TSPPISLSSFFWLGLSWHPSE---GNWLWEDN----V---IPSPSLFSSTEL---AHL--
-----NGSKGCAYFQRGNIY--------------VSRCSAEIS---WICEKTAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------YR
VFQQ---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

LKTWNDSRDFCIARNSTLLHVENMEEL-------------------EFIQTKL
Q-------EFSWIGLT-RQRPT--SPWMWVNG----S---ALSSALNI---------LEP
---NQKLENSCGILSNDSLQ--------------AKACQDISH---FVCEKKSC------
--------------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTV---AIWRPN----------S-------
----------------------GSNSLENGYFPSRNKE------NHSQPTQSSLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GL---LSSPCPPNWIIYEKSCYL
FSLS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCLQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

-----------------------------------------MTAPPGARMQAKYSSTRDM
RDMLDDDEDTTMSLHSRASTTTW-------QP--------EP-------RRAEL-RNP--
---LSRWRPVALTLLALCLVLLTGLA--ALGLVFFQFYQLSNAQQAVIAQREE-------
---------------------------RLGNLSQELQSLQVKNKKLAESLHRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGPQCSPCPEKWKWHGDKCYQ
FYRD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCNADNSTMLKINTQEVL-------------------DFAMHQS
YSEF---FYSYWTGLS-RNGGG--KTWLWMDG----T---PYSFELFEI--IIDSS----
----VLRSRDCVTILNGKAF--------------SKDCRELRR---CACERLAGRVD-PE
RLH-----------------------------------------------------

------------------------------------------------------------
--MSEDVTYS-------TLTLQDSAGTGNCQDRNNFRTK--------D------SSVS--
---PTNWRQAALGLLALCLLLLIGLV--TMGILYFQTENK----------VNS-------
---GSEKLTQLLQVIEQQRANSSRQQTTTRDLLEKEKSLKSQISELLRWQKKIAT-----
------------------------------------------------------------
---------KLCQ-ELVTHT-------------------SDHKCNPCPKTWHWYQDSCYY
FVTT--

PF00059 // ENSGT00700000104266_Domain_2 (367, 457)

EEKNWDNSRDDCVGKESSLVKIETQEEK-------------------DYL----
KSRPLPKYSFFWLGLSLDPST---STWLWEDG----S---IPSPSMVCW-----------
------------------------------------------------------------
--------------------------------------------------------

-------------------------------------------------VWIDFFTYS--
-SMSEEVTYA-------DLKFQNSSETEKIQE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLTVLCLLTLIGLG--VLGSMFH----------IT---LKT-------
---AMKKMSKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--TSYPYWLGLS-PEKDY--SYGTSVDN----I---INSSAW----VIRNASDL-N
N-------IFCGYINRIYVH--------------YDYCIYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MSEDITYA-------SLKLPESRKTENIQE---LDR-----SGTKA------LPAS--
---SRIWRQTTLILTLICLLLLIGLG--ILGSMLY----------TT---WKI-------
---ETGKLNKLQNVKEELQRNISIQLITNMNKSE-------NIRNLSITLQNLAT-----
------------------------------------------------------------
---------KLCR-ELNREE-------------------PGHKCKPCPNGWMWYKNNCYL
LSEM---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWKESEISCSAQNASLLKIKESTTL-------------------EFV----
KSKN---LYSYWLGLP-PEKDR--RNSEEVDK----I---IVSSAR----IMRNVNDINK
--------MYCGYIYRSMVV--------------YNHCTTKYY---SACEKKANPVN-VE
SVVMSEDPVRRI--------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------LCTA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRSN----------S-------
----------------------GSNTLENGYFLSRNKE------NHSQPTQSSLED----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLLKIDSSNEL-------------------GFIVQQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQMCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------YPAP--
---SPIWRQAALSLLTLCLMLLXXXX--XXXXXXXXXXXX----------XXX-------
---XXXXXXXXXXXIHQQQNLFQQ--GHYR-NPMEEEFFKSQIADLLRRQGEMAI-----
------------------------------------------------------------
---------KLCQ-ELVIHN-------------------SGHKCNPCPRTWQWYQNSCYY
FTTN--

PF00059 // ENSGT00700000104266_Domain_1 (367, 393)

EEKTWVNSRKDCMDRNSTLVKIDSLEEK--------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSSQTENIQK---FDK-----FEKEE------PPVP--
---SHVWRQRALALTVLCLLLLIGLG--VLGGIC--------------------------
----MEKLNKLQNFKEELQRNMSLQLMQNTNSSQ-------KIRNLSIKLEEIAT-----
------------------------------------------------------------
---------KLCR-ELYIKN-------------------KGNKCKPCPEEWMWHDDNCYL
LLSGYQH

PF00059 // ENSGT00700000104266_Domain_2 (368, 451)

RKTWQKSDEICSDYNASLLTIKSKRVL-------------------EFI----
KSLQ---LNHYWLGLS-PRKDD--KKYGNLD-----T---SIPFDW----FTRNTSVISD
K-------MYCGYIQYIEYY--------------YHVSHMPNL---SLLHIWKR------
--------------------------------------------------------

------------------------------------------------------------
--MSEDMTYA-------TLTFQDSISAGNNQDRNNLRKR--------G------YPAP--
---SSIWRQAALGLLT--LMLLIGLV--TLGIMFLQMSSE----------INS-------
---DSDKLTQLQQITHQQQDNLSQQLSEYRNFPVEEEFLKSQISSLLNRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHKCNPCPKTWKWYQTNCYY
FAIN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWPNSRKNCMDKNSTLVKINSLEEK-------------------DFL----
RSQPLPKFPFFWLGLSWDPSG---RSWLWEDS----S---RPSPSLFSANEY---AQI--
-----NESKGCAYFQNGNTY--------------ISCCSAEIS---WICEKTAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------DLKFQDSDKKEESQK---SDK-----CGRKV------PSAG--
---SYSQHKTVLILILLCLLLFIGVV--ALGCIFY----------TT---LET-------
---EMIKSNQLQRVKEELQENVSLQLMHNLNNSK-------KIKTLSAMLQNIAT-----
------------------------------------------------------------
---------QLCQ-ELSKKE-------------------PGHKCKPCPKASDWYKDSCYS
RFQK---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 436)

ATWQESVEFCSARNASLLKVKNKDEL-------------------EFI----
KSKE---LYNYWLALP-PSKMY--RSYELLSE----K---MFLSEG--------------
------------------------------------------------------------
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDFDRDTIMSVPSRASSTTQ-------QP--------EA-------GHTGR-RPP--
---SSVWRPVALTLLTLCLVLLIGLL--ALGLVFFQFYQLSNTQQDSISHKEE-------
---------------------------RLGNLSRQLQSLQTRNRKLAEILQRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GEHRCSPCPEEWKWHGDKCYR
FYRE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 530)

-SKNWQGCEYFCIAENATMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSG--KVWLWTDG----A---LYFPELFEI--TIDFT----
----SLRSRDCVTILNGKAF--------------SKDCKELRR---CACERKAAMVK-PE
SFH-----------------------------------------------------

------------------------------------------------------------
-MMSEEVTYA-------TLMFQDSVGERNNRDRNYLRNR--------E------YPAP--
---SPIWRQAALSLLTLCLLLLIGLV--TLGIMFLQTSNE----------INS-------
---DSEKLSQLQKIIHYQQNNLSQQLSNYRSFPTEEKFLKSQISSLLRRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHKCNPCPKMWQWYQHSCYY
FATN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

ENTWTNSRKYCMDKNSTLMKIDSLEEK-------------------DFL----
KSQPLPTLSFFWLGLSWDPSG---RNWLWEDG----S---VPSPSLFSTKEY---AQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIS---WICEKMAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSEDVTYA-------TLTLQDSAGTKNNQDGNNLRKK--------G------HPAR--
---SPIWRHATLSLLTLSLMLLIGLV--TLGIMFLQISNE----------INS-------
---ESEKLSQLQKTIHQQQDNLSQQLGNYNNFPLEEGFLRSQISSLLKRQGQMAI-----
------------------------------------------------------------
---------KLCQ-ELISHI-------------------SDHRCNPCPKTWQWYQNSCYY
FTTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWTSSRKDCIEKNSTLVKIDSLEEK-------------------DFL----
KSQPLPMFSLFWLGLSWHQSG---KSWLWEDG----S---VPSPSLFSTKEL---AQI--
-----NGSRGCAYFQKGNIY--------------ISRCGAEIS---WICEKTAALVK-IE
DLE-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKCKT----MQDQLGQ-------KPNEEKA---KGLHCLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 150)

SWWWCPAAVTLGILCLGLLVTTA--M

ENSGT00700000104266_Linker_0_2 (150, 367)

LILQXXXXXXXXXXXXXXXXXXXXXXXXXXX
X---------------XX-XXXXXXXXXXXX-------XXX-XXXXXXXXXXXXXXX---
------------------------------------------------------------
----------------------XXXXXXXXXXXXXXXXXXXXXXXPCPQDWLWHAESCYL
FSSA--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-PSNWEKSHENCLSLDAQMLTINSTDDL-------------------EFMRQAS
A----HSSFPFWMGLS-LKKPK--NSWLWEDG----S---PLKTHVFS---------LQG
AASPTHLSGTCAYIQRGKVF--------------ADNCILTAF---HICQKKANLLR-VQ
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSTG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKN-LRA-Q-
--------------------------------------------------------

-----------------------------------------M-SIQGLSRTMEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCVA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GSNSLENGYFPSRNKE------NHSQPTQSPLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSPS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

-------------------------------------------------MQTKYSSERDV
RDMLDDDEDTTMSLHSRASTLTW-------RP--------EP-------RHT--------
---------------------------------VFQFYQLSNIQQAIITEKEE-------
---------------------------RLGNLSQQLQSLQVKNKKLADTLQRVAE-----
------------------------------------------------------------
---------KLCR-EL

PF00059 // ENSGT00700000104266_Domain_2 (317, 531)

YNKS-------------------G--------------------
---------------YFCSAENSTMLKINAQEVL-------------------DFSMLQS
YSEF---FYSYWTGLS-RNGSG--EAWLWMDG----T---PYSFQLFEI--IIDAS----
----NLRSRDCVTILNGKAF--------------SKDCRELRR---CACERTAGRVD-PE
KLH-----------------------------------------------------

------------------------------------------------------------
--MQEEEMYTSLQWDNPTSN-----------PYQ------------KN-------LP---
SKCSGTRCLVIVISCIFCMGLLTTSI--FLGIKLFQVSAIAVKQQEKLIQQERTLLNF--
--------T-------QCNRNHDF-----------------QMKCCQILGKMFIFK-A--
------------------------------------------------------------
-----------------------------------------HHCSPCPDNWIQNGESCYY
VFEN---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

HKTWHTSKQVCLKEGSNLLQIDNKEEM-------------------DFITGSL
KRI--KSSYDYWVGLS-QDGLS--GPWLWQDG----S---SLSPDLWPV-----------
-QRPQSPNLVCGYLKNKILF--------------SANCSSWKH---FICEKYALRSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVALNIKTRRSAFTS------------------------A------DPVS--
----SLWRVMAFVLLILCTGMVVGLV--ALRIMSVT------------------------
------------------QQ-------------N---LLQAENENLSGTLQRI-LR----
------------------------------------------------------------
---------SA-----------------------G--NTECHKCSPCDKNWRYYGDSCYG
FFKH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NLTWEESKQYCSGVNATLPKIASQNIL-------------------EYI----
KART---GLIRWVGLS-RQNSN--GVWMWEDG----SVGSVFSKNM----PE-----L--
-PGDGRENMNCAYFHNGKIH--------------PSFCKNKHY---LICERKAGMAK-VD
KLL-----------------------------------------------------

---------------------------------------------------MDPHPDF--
-ENVDEDGYTKLNFNTQDATRS-------------------PVGSKKG------LSGI--
PAASPAWRLIAVILGILCLIILVIAV--VLGSL---------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------GV---FSSTCPPNWIAHEKSCYL
FSIS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWYGSKRRCSQLGSHLLKIDTLKEF-------------------DFIVGQM
SSY---PNNSFWIGLS-RNQTE--SLWVWDDGS-------TFSYNFLQ---------IRS
TATQENTPHNCVWLHVGNAY--------------DQPCNILSF---SVCERLLSG-----
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------MLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNFSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWTNSRKDCTDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSIFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DLN-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---SSLWRVMALILLVLCIGLVVGLV--ALGIMSFPFALIS-FQHSFIH-----------
-----ISKKKIFS-NSVTQQ-------------N---YLQIENKNFSGILQQLLAN----
------------------------------------------------------------
---------QFCQ-DLMKPS----------EQKDS----FSHKESPCDKNWRYYEGNCYG
FFRH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NLTWEESKQYCANMNATLLKIASQNIL-------------PFFMNKEYI----
KSRT---GLIRWVGLS-RQNAN--KVWKWEDG----S---VPSKNM----FE-----L--
-SENAKENMNCAYFHNGKIH--------------PSFCKNKHY---LMCDKKAGMAK-VA
KLL-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MGLLVTII--MLGMQLFQVSDLLKQYQANLTHQEIIREGQIL
AQQQAKNAS--QKSQEELKEMIEILALKLDEKSRKQMELHQQNLDLQEALKRVENFS---
------------------------------------------------------------
--------------------------------------------GPCPQDWIWHEESCYL
FPSG---LF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQENCLSLGAQLLKINNTDDL-------------------NFIQQAI
S----HSSFPFWMGLS-LRKPN--YTWLWEDG----S---PLMPHLFR---------LQG
AVSQMYASGTCAYIQRGAVF--------------AENCILVAY---SICQKKAVLLK-AL
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--S
NKCSGAWCLVTVISCIFCMGLLTASV--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WR

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-EISQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQNSTETENIRE---IDK-----FGEKA------PPSP--
---SRVWHPAALFLTLLCLLLLIGLG--VLGSTFY----------IT---LKT-------
---EMEKVKELQNINEELQRNVSLQVMSNINSSN-------KIRNLSTTLQTTAT-----
------------------------------------------------------------
---------KLCR-ELYREK-------------------KDHKCKPCPKRWMWHEDSCYF
LSDD---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKMACAAQNASLLKINNKSAL-------------------EFI----
KSPN--RLYGYWLGLS-PEKYY--IYSKSIDN----I---IN-SDW----VIRNSSDL-T
N-------MYCGYIDGSYVT--------------YCLCTYQKR---TICEKMANPVQ-LD
FIHFTEA-------------------------------------------------

------------------------------------------------------------
--MSDQVTYA-------TLTLQDSAGARNNRNGNNLRKR--------G------HPAP--
---APAWRQAALGLFILCLMLLIGLV--TLGIMFLQMSNE----------MNS-------
---DSEKRNQLQKIIHQQQDNLSQQLDNHRNLPAQEESLKSQISDLLKRQGQLAI-----
------------------------------------------------------------
---------RLCE-ELIIHM-------------------SDHRCNPCPETWQWYQNSCYY
FITN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWTSSRKHCMDKNSTLVKIDSVEEK-------------------NFL----
KSRPLPVSSLFWLGLSWDHSG---RDWLWEDG----S---IPSPSLFNTKEL---AQI--
-----NGSKGCAYLQKGNIY--------------ISRCSAEIS---WICEKTAALVK-ID
DLD-----------------------------------------------------

---------------------------------------------------MEKVSDL--
-GNLDEEGYTQLDFSTQCTTRK-------------------PVFSEKG------IHAA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 153)

PLHWRCIAVILGILCLALMVIAV--VLGT

ENSGT00700000104266_Linker_0_2 (153, 367)

M---AIWRSR----------Q-------
----------------------GRSPFEEGGLISRNTE------SHTQPLAHSLDK----
------------------------------------------------------------
---------NXXX-XXXXXX--------------------XXXXXSCPPNWITYKNSCYL
LGTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-MDSWEGSKRQCSLLGSNLLKIDNSEEL-------------------EFIRRQV
SLR---PHHSFWIGLS-RSQTE--GPWLWEDG----S---PVFPNLFQ---------VQN
TVPQGSTSHYCVWIHVSIIY--------------DQLCSIPSF---RICEKKLPV-----
--------------------------------------------------------

------------------------------------------------------------
--MNLEMTFD-------D-KMKP----VNEQPDQ-------KLCHKKA---KGLRFLS--
---SQWWCPVAMTLVILCVGLLVIVI--IQWMQLLQVSDLLKQYQANLTRQEHTIEGQIL
AQQQTANAS--Q---QKLKETIDTLTWELKEKTKEQEGLLQQNLNLQKALQRAANFSVL-
----QV---SDLLRKYQANLTHQER------ILERQILAQQQAANASQQKL---------
----KETIDTLTW-ELKEKTKDQEELLQQNLNLQKALQKVANFSGPCPQDWLWHKENCYL
FSSA---QS

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

YWAKSQENCRALDAQLLQINSIDNL-------------------NFILQAT
S----HSTSPFWMGLH-RKKKN--DPWLWENG----S---PLRPHLLK---------IRG
IPSQAHPSGTCVYIQEGGIF--------------ADHCILNAF---SICEKQAQLLP-TE
--------------------------------------------------------

---------------------------------------------------ME---YQ--
-ETLDEDGYTQLDFRTRGILKR-------------------PVESEKG------SRSS--
---SLPWRPIAVALGILCLVALVVAV--VLGVL---GEYGFN----------S-------
----------------------GRNPEEKENFPSRNKE------NH-KPTKSSLDE----
------------------------------------------------------------
---------KVAP-SKASQT---------------T-GL---YSGPCPPNWIIHEKSCYL
FKTS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

QNSWAGSKRYCSQLGAHLLKIDNSEEF-------------------EFIESQT
SSH---HINAFWIGLS-RKQTE--GPWLWEDG----S---PFIPNSFQ---------IRD
TASQESLLHNCVWIHGSEVY--------------NQVCNISSF---SICEKQLQ------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPQKPAPSS------------------------V------DPAS--
---SSWWRVMSLILLILSLGMVAALV--ALGIMSVT------------------------
------------------QQ-------------N---NLQAEKENLSGTVQNL-AK----
------------------------------------------------------------
---------NFCQ-HIIQQL----------EENQK--RSADHKCSPCDTNWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKRYCSNRNATLTKTASKNIL-------------------DYI----
KDRT---VFIRWVGLS-RQNAD--KVWMWDDG----S---VLSKNM----LE-----F--
-FEDGGENMDCAYFHKGKIY--------------PTFCKNRHY---LMCERKAGMTN-VD
QLL-----------------------------------------------------

-----------MTHTEHLC------------QTAIVEKS----TCGDGVRLVFLCLKP--
-SMSEEITYA-------DLKFQDSSEKENIYE---FDG-----VGIKA------PPVP--
---SHGWRRRTLALTFLCLLLLVGLG--VLGSIFY----------TT---LKI-------
---ETGKLNKMQIFKEELQKNVSLQLIHNKNSSK-------MIRDLSITLQEIAT-----
------------------------------------------------------------
---------KLCH-ELYKRE-------------------PEHKCKPCPKAWMWHEDSCYV
LSDH---D

PF00059 // ENSGT00700000104266_Domain_2 (369, 461)

ETWQESVMSCSAQNASLLTIKSKSVL-------------------EFI----
KSKK---LRGYWLGLS-SEEY---QGYQKLDE----T---IISSNW----TISSTWCLLE
EVKKRKIRDVCGGRSLNLVTTCIDHATGAASVKFSETCTTPSDQQCCICSVCLKK-----
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPIWRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNLSQQLGNSNNLSMEEEFLKSQISSLLKRQEQMAV-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 464)

EKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLYVSNY---------
------------------------------------------------------------
--------------------------------------------------------

-------------------------------------------------VWIDFFTYS--
-SMSEEVTYA-------DLKFQNSSETEKIQE---IAK-----FGGKA------PPAP--
---SRVWRPAALFLTVLCLLMLIGLG--VLGSMFH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--TSYPYWLGLS-PEKDY--SYGTSVDD----I---INSSAW----VIRNASDL-N
N-------MFCGYINRIYVH--------------YDYCIYRKK---MICEKMASPVQ-LG
FIHFRDA-------------------------------------------------

-------------------------------------------------MQAKYSSTRDM
RGMLDDDEDTTLSLHSQASATTW-------QP--------EP-------RPTEL-RTP--
---LSTWRPVALTLLTLCLVLLTGLA--ALGLVFFQFYQLSNTQQAIIL-----------
------------------------------------QSLQGKNKKLAESLHRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGPKCSPCPEKWKWHGDKCYQ
FYRD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCNAENSTMLKINTQEVL-------------------DFAMHQS
YSEF---FYSYWTGLS-RNGSG--KTWLWMDG----T---PYSFELFEI--IIDTS----
----LLRSRDCVTILNGKAF--------------SKDCRELRR---CACERTAGRVD-PE
KLH-----------------------------------------------------

------------------------------------------------------------
--MSEEITYA-------DLKFQNSNEMEKIEE---IGK-----FGEKA------PPSR--
---SRVWRPAALFLTLLCLLMLIGLG--VLASMFH----------IT---LKI-------
---EMKKMNKLQNINEELQRNFSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------KLCR-ELYSKE-------------------QEHKCKPCPGRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--RSRDYWLGLS-PENGY--TPDMRVDN----I---INSSAW----VIRNAPNL-N
N-------LHCGYINRLYVY--------------YSYCTYEKR---MICEKMANPVQ-LG
FIHFMEA-------------------------------------------------

------------------------------------------------------------
--MHEEEMYSSLQWDSPAP-D----------TYQ------------KC-------LS--S
NKCSGACCLVMVISCIFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHAL-----------------QMKYCQAFMQNSLSS-A--
------------------------------------------------------------
-----------------------------------------HNSSPCPNNWIQNRESCYY
VSEI---WSI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--KGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERSQSTNQVCGYMKNNSLL--------------SSNCSTWKY---FICEKYALRSS-A-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPALVS------------------------V------GPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWQESKQYCTDMNATLLKIDNQNIV-------------------EYI----
KART---SLIRWVGLS-RQKSN--EVWKWEDG----S---GISENM----YE-----F--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENRHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRM-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRSN----------S-------
----------------------GSNTLENGYFPSRNKE------NHSQHTQSSLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLLKIDSSNEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQASATTR-------RP--------EP-------RCTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--ALGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNMSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------DFAVSES
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFTSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CVCERRAGMVK-PE
NLHFPPEILGESD-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----TWCLVTVISCIFCMGSLATSI--FLAIKLFQISTIVMQQQEKLIQHDRTLLNL--
--------T-------QWRRSHDL-----------------QEKCLQNFMQNSFS-----
------------------------------------------------------------
----------------------------------------AHNCSPCPENWIQNGESCYR
FVEN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WKIWHTSREDCWKEGSKLLQIDSKEEM-------------------EFITGTL
KTT--KRGHDYWVGLS-QNGLG--EPWLWQDG----S---SPSPNLWSN-----------
-QRPQSTDNICGYLKDKLLL--------------PANCSSWKY---FICEKYSLRST-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNLKSRKPALTS------------------------V------DPAS--
---SSLWRMMTLALLVLCVGMVVGLV--ALGILTVT------------------------
------------------QQ-------------R---YLQDENVKVSGTLWQL-AR----
------------------------------------------------------------
---------KVCQ-DLIKEL----------EKKEPKSTRKGHKCSPCDKNWRYYGDSCYG
FFKH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NFTWKGAQKYCADKDSSLVKITSKNVL-------------------EYL----
KDRT---SLIRWAGLS-RQNSN--EDWEWEDG----S---VVSKNI----FE-----L--
-SGNARENMNCAYFHNGKLY--------------PAFCENDYY---LICEKKSGMAK-VD
ELL-----------------------------------------------------

----------------------------------------------------MEYPDL--
-ENLDEDGYTQLRFNSRNNTRI-------------------SVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVTAV--VL---GTTAFWRSN----------S-------
----------------------GSNPLKNGNFPSRNKE------NHSQPTQSSLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GD---LSSPCPPNWIIYEKSCYL
FSTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLDSNLLKIDSSKEL-------------------GFILKQV
SSQ---PDNSFWIGLS-RTQTE--GPWLWEDG----S---TFSSNLFQ---------IRT
TATQENSSSNCVWIHVSIIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
--MQEDETYTSLQWDTPTSN-----------PYQ------------RH-------LS--S
TKNSGVWCLVTVILCIFCIGSLATSI--FLGIKLFQMSTAIMQQQEKLIQQERALLNF--
--------S-------QWKRNPNL-----------------QMTYCQTLMQKSFS-----
------------------------------------------------------------
---------------------------------------SAYNCSPCPNNWIQNGESCYY
VFES---WKF

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSREDCWKKESDLLQIESKEEM-------------------DFITGSL
TKI--KRNYDYWVGLS-QNGSN--QPWLWQDG----S---SPSADLLPR-----------
-QAPQSTDQVCGYLRDNGLS--------------SANCSVWKY---FICEKYALRSS-T-
--------------------------------------------------------

---------------------------------------------------MEYHSDV--
-ENVDEDGYTQLHFNSPGISRI-------------------PMVSEKG------TCGA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 212)

SLPWRPIAVALGILCLIILVIAV--VLGTM---AIWRSN----------S-------
----------------------KSNSLENDN

ENSGT00700000104266_Linker_0_2 (212, 369)

FPPRNKE------NHSHPTQSSLEE----
------------------------------------------------------------
---------SVAP-TKALKT---------------T-GVPEIPSSSCPPNWIRHEKSCYL
FRTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DTWNRSKRQCSQLSSNLLKIDSSKEL-------------------EFIIRQV
SSQ---PDYSFWIGLS-RPQPE--GQWLWEDG----S---TFSSNLFQ---------LRS
TATQENSSPGCVWIHVSIIY--------------DQLCSVPSY---SICEKKLSV-----
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------CPENWFPHGEKCYH
FSTE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

TRSWLESQKACCSSGSRLLLIENKEEL---------------------VEQDF
ISP---LAHSHWIGLS-RDRTD--KPWMWGNG----T---AFSTDHSL-----------T
GLQKGYMDGDCAFIIGGDLT--------------SGPCNDAKR---YICEQLVL------
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSGKKENTQE---FGN-----FGIKV------PPAP--
---PHTWRQRALVLTLLCVLLLIGLG--VLGGIL--------------------------
----VEKLNKLQNFNEELQRNVSLQVIHDMNSAK-------KIGNLSITLQEIAT-----
------------------------------------------------------------
---------KLCH-QLSIEK-------------------PEHKCKPCPKNWMWHEDSCYI
VIKL---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

PETWQKSDMLCSAQNASLLKIKNKSVL-------------------EFI----
KSRK---IYASWLGLS-PRKTH--TVSRKLDE----T---IISSDW----FTRNTNDLND
S-------MYCGYLYNNRVN--------------YADCTETKR---IICEKLADPMK-IE
DILTSEEPAGRM--------------------------------------------

----------------------------------------------------MEYPDL--
-ENLDEDGYTQLRFNSRNNTRI-------------------SIVSEKG------IYIYMI
LCCISSLAFICCVLGILCLVILVTAV--VL--VPRVTIWRSN----------S-------
----------------------GSNPLKNGNFPSRNKE------NHSQPTQSSLEE----
------------------------------------------------------------
---------SVTP-TKAIKT---------------T-GD---LSSPCPPNWIIYEKSCYL
FSTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLDSNLLKIDSSKEL-------------------RFILKQV
SSQ---PDNSFWIGLS-RTQTD--GPWLWEDG----S---TFSSNLFQ---------IRT
TATQENSSPNCVWIHISIIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------NLKIQDPDKKEETQK---SDK-----CGGKV------SADA--
---SHSQQKTVLILILLCLLLFIGMG--VLGGIFY----------TT---LAT-------
---EMIKSNQLQRAKEELQENVSLQLKHNLNSSK-------KIKNLSAMLQSTAT-----
------------------------------------------------------------
---------QLCR-ELYSKE-------------------PEHKCKPCPKGSEWYKDSCYS
QLNQ---YG

PF00059 // ENSGT00700000104266_Domain_2 (370, 530)

TWQESVMACSARNASLLKVKNKDVL-------------------EFI----
KYKK---LRYFWLALL-PRKDR--TQYP-LSE----K---MFLSEE----SERSTDDIDK
--------KYCGYIDRVNVY--------------YTYCTDENN---IICEETASKVQ-LE
SVLNGLPEDSR---------------------------------------------

-----------------------------------------------------FFTYL--
-SMSEEVTYA-------DLKFQNSTETENIQE---TDK-----FGRKA------PPAP--
---SRVWRPAALFLTLLCLLLLIGLG--VLGSIFY----------IT---LKI-------
---EMEKVNELQNINEELQRNVSLQLMSNMNSSD-------KIRNLSTTLQTTAT-----
------------------------------------------------------------
---------KLCR-ELYRGK-------------------KEHKCKPCPERWMWHGDSCYF
LSDD---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 451)

QTWQESQKACAAHNASLLEINNKSAL-------------------EFI----
KSQN--KLYGYWLGLS-PKKDQ--TNHKIVDD----I---INSSDW--------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------D-KMKP----ANDEPVQ-------KSCGKKP---KGLHLLS--
---SPWWFPAAMTLVILCLVLSVTLI--VQWTQLHQVSDLLKQYQANLTQQDRILEGQML
AQQKVENAS--QESKKELKGKIDTLTQKLNEKFKEQEECLQKNQNLQEALQRAANSSEES
QRELKGKI-DTITQKLNEKSKEQEELLQMIQNLQEALQRAANSSEESQREL---------
----KGKIDTLTL-KLNEKSKEQEELLQKNQNLQETLQRAANFSGPCPQDWLWHKENCYL
FHGP----F

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWEKNRQTCQSLGGQLLQINGADDL-------------------TFILQAI
S----HTTSPFWIGLH-RKKPD--QPWLWENG----T---PLNFQFFK---------TRG
ISLQLYSSGNCAYLQDGAVF--------------AENCILIAF---SICQKKTNLLQ-I-
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------SPAL--
---APLWRPAALSLLTLCLMLLIGLV--TLGIMXXXXXXX----------XXX-------
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
------------------------------------------------------------
---------XXXX-XXXXXX-------------------XXHRCNPCPKSWRWYQNSCYY
FTTD--

PF00059 // ENSGT00700000104266_Domain_2 (367, 457)

TEKTWTNSRKDCTEKNSTLVKVDSLEEK-------------------EFL----
KSQPLAKFSFFWLGLSWEPFS---RNWLWEDG----S---IPSPSLVSAW----------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYIMLDFKSRIHATSK------------------------G------APGL--
---PPSWRWMTLALLILCLGMLIGLT--VLGSMLANIHSP--------------------
--------------------------------------ASPTDSRQQALLQQI-TQ----
------------------------------------------------------------
---------KYCQ-ELSSKP----------GGKII----KCHKCSSCDHNWRFHGGKCYG
SFKN---

PF00059 // ENSGT00700000104266_Domain_2 (368, 484)

NKTWEESKKYCDDRNSTLLKIDTQEAW-------------------NFI----
QGRP---DFTRWIGLS-RPSSG--GRWTWMDH----S---ALTDNL----RE-----K--
-HEAQKGGVTHLWLHN--------------------------------------------
--------------------------------------------------------

-------------------------------------------------MWIDFFTYS--
-SMSEEVTYA-------DLQFQNSSEMEKIPE---IGK-----FGEKA------PPAP--
---SHVWRPAALFLTLLCLLLLIGLG--VLASMFH----------VT---LKI-------
---EMKKMNKLQNISEELQRNISLQLMSNMNISN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------KLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--RSYDYWLGLS-PEEDS--TRGMRVDN----I---INSSAW----VIRNAPDL-N
N-------MYCGYINRLYVQ--------------YYHCTYKKR---MICEKMANPVQ-LG
STYFREA-------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQASATTR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNMSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------DFALSQS
YSEF---FYSYWTGLL-RPDSG--KTWLWMDG----T---PFPSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CVCERRAGMVK-TE
SLHFPPETLGEGDWFS----LCNYK-------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLAAATLGVLCLGLVVTIM--VLGMQ---------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------PPCPQDWIWHGENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------VRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNVKSQKPGLTS------------------------G------ESAS--
---SSWWRMLALILLVLCMGMVVGMV--ALGIISVT------------------------
------------------QQ-------------N---YLQTENEHLSGALEQL-AK----
------------------------------------------------------------
---------NFCQ-HLSKQL----------EPKSK--YGLGHKCSPCDANWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWEESKQYCTDRNAILLKIANQNIL-------------------EYL----
KGRT---GLIRWIGLS-RQNSN--GTWMWEDG----L---VLSKNM----SV-----L--
-PEDRRENMNCAYFHNGKIH--------------PTSCKNKHY---LMCERKAGRVK-LD
QLL-----------------------------------------------------

------------------------------------------------------------
------MTFD-------D-KMKP----ANDEPVQ-------KSYGKKP---KGLHLLS--
---SPWWFPAAMTLVILCLVLSVTLI--VQWTQLRQVSDLLKEYQVNLTEQDHILEGQML
AQQKAENAS--QESRKELKGKIDTLTQKLNEKSKEQEELLQKNQNLQEALQRAADSSEES
QRELKGKI-DTITRKLNEKSKEQEELLQMIQNLQEALQRAANSSEESQREL---------
----KGKIDTLTR-KLNEKSKEQEELLQKNQNLQEALQR-----GPCPQDWLWHKENCYF
FHGP----F

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWEKSQQTCLSLGGQLLQINGADDL-------------------TFILQAI
S----HTTSPFWIGLH-RKKPD--QPWLWVNG----T---PLNFQFFK---------TRG
ISLQLYSSGNCAYLQDGVVF--------------AENCILTAF---SICQKKTKLLQ-I-
--------------------------------------------------------

-------------------------------------------------VWIDFFTYS--
-SMSEEVTYA-------DLKFQNSSETEKIQE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLTLLCLLMLIGLG--VLGSMFH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---G

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--TSYPYWLGLS-PEKDY--SYGMSVDD----I---INSSAW----VIRNASDL-N
N-------KFCGYINRIYVH--------------YDYCIYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------HLKLRDSVKKENMQK---SEK-----HRGEV------PSAP--
---SCSQHKTVLILILLCLLMLVGLG--VLGGLFH----------TT---LET-------
---EIIKSNELQGIKEELQRNISLQLMLNHNSSK-------IIGNLSAMLQKTAT-----
------------------------------------------------------------
---------QLCR-ELYKKE-------------------PEHKCKPCPKGSKWYKDSCYF
KLGG---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

RTWQKSEIQCSVQNASLLKIKNKSVL-------------------EFV----
KSER---LNNYWLGLS-PRKDQ--AKSEKLTE----T---IFLSAG----FEGSMPDLSK
--------MYCGHIQGMYVY--------------YSPCIWEKN---VMCEGTASNVQ-VE
SVLNDLPEESL---------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGTSTVTR-------RA--------EP-------RHSEN-GTP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNIQQDSITEKDE-------
---------------------------KLGNMSRQLQSLQTQNRKLIETLQQVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWYGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKNWQSCEYFCLADNATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERIAGRVV-PG
ELQ-----------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVRGNQDGNNLRKE--------G------HPAQ--
---SSLWRGAALSLMTLCLVLVTGLV--TLATMFLQVSND----------INS-------
---DSEKLSQLQKSIHPQQDNLSESLNSSRKSLTEE-SLQSQISALLERQEQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHA-------------------SDHKCNPCPKTWQWYGNSCYY
FSIN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKSWSDSRKDCIDKNATLVKIDSTEER-------------------DLL----
QSQLSLTFSFFWLGLSWNSSG---RNWLWEDG----S---FPPPTLLSDKEL---ASF--
-----NGSRQCAYFERGNIY--------------ASRCRAEIP---WICEKRASLVK-IE
DLD-----------------------------------------------------

-------------------------------------------------MLAKYSSTR--
-DMLDADGDTTMSLHSQASATSQ-------RP--------EL-------GHTEH-QRP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDSILQKEE-------
---------------------------KLGNLSRQLQSLRTQNRKLAETLHHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNSSG--KAWLWMDG----T---PYSSELFDV--MIDLT----
----SLRSRDCVTILNGKAF--------------SKDCRELRR---CACEKAAAMVK-VQ
SLHEPLSRRWR---------------------------------------------

---------------------------------------------------MEYHSGL--
-ENLDEDGYTQLDFSSRDITRR-------------------PVVSEKG------TCAA--
---SPRWCPI

PF05473 // ENSGT00700000104266_Domain_2 (131, 530)

AVTLGILCLVILVIAV--VLGTM---------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------GV---LVSSCPPNWIMHENSCYL
FSTS---LDSWDRSKRQCSQLGSTLLKIDSSEEL-------------------EFIARQV
SSQ---PDNSFWIGLS-RHQKE--GPWLWEDG----S---IFSSNLFQ---------IRS
TVMEENSSHNCVWIHLSIIY--------------DQLCSVLSY---SICEKKL-------
--------------------------------------------------------

------------------------------------------------------------
------MTSD-------DLQSKT----MRSQPDQ-------ESHEEKA---KGLYFHS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 175)

PGRWYAATVTLGILGLGLLVTIL--VLVVQLYQVSDLLKQQQANLTCQENMSEGQFL
AQQGTEKSS--KESQTELKEMIETLSQMLDEKSKILTDLQQQNLNLQEALKKAANYS---
------------------------------------------------------------
--------------------------------------------GPCPQDWIWHEKSCYF
FSSG---PFNWETSQENCLSLGAQLLKINSTEDL-------------------EFISQAX
X----XXXXXXXXXXX-XXXXX--XXXXXXXX----X---XXXXXXFR---------LRG
AVTQKYPSDTCAYIQRGTVF--------------ADNCILSAF---SICQKRAILLQ-AQ
--------------------------------------------------------

-------------------------------------------------PELTCSPRE--
-AMLDEDGYITLNIKNRKPALTSEK---------------SPLGKDRF------DPAS--
---SPLWRVTALILLVLCMGLVVGLV--ALGMMPSGYQDILNNGE-LLL-----------
-----FLLTQIDS-STEIEL-------------N---HHQVENKNVSGTLHQV-AK----
------------------------------------------------------------
---------KFCQ-YLIKQL----------EQKNS----VSHKCSPCDRNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWEESKQFCINMNATLLKIASQNVL-------------------EYM----
KSRT---GLIRWVGLS-RKNST--EVWMWEDG----S---VPSKNVLFQ-FE-----L--
-SGNERENMNCAYFYDGKIY--------------PTFCKNKHY---LMCERNASMIP-PH
PFFIYPLLLRQGD-------------------------------------------

---------MPAPEERLLM--------DSSSPAAWGKRST--PHAAGIRMQAKYSSTR--
-DMLDDDWDATMSLHSQAPSTPR-------RP--------EP-------RQAEP-KTS--
---SSAWRPVALTLLTLCLVLLIGLA--ALGLVFFQYYQLSNNQQDSISRKEE-------
---------------------------RLGNFSKEVQSLQAQNRKLAETLLHVAV-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GGHQCNPCPEKWKWHGDRCYQ
FYKE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

SRSWQGCEYFCFSENSTMLKINTQEVL-------------------EFAMPQS
HSEF---FYSYWTGLS-RNSSG--KMWLWTDG----A---PFNFELFEI--VVDVT----
----SLRSRDCVTILNGRAF--------------SKDCRELRR---CACERTAGTVR-PE
KLLQNS--------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKTDNQNIL-------------------EYI----
KART---GLIRWVGLS-RQKSS--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------LPSQPCPRSWSRHGASCYR
LVWS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWNGSRRRCSRLDSALLAIESPEEF-------------------DFVRSQT
SLH---PANAFWLGLS-RRGAQ--GPWLWEDG----S---ALSPDIFP---------VRS
AATQEGAPDSCAWIHGSDIY--------------AQLCHTPAF---SICKRLS-------
--------------------------------------------------------

---------------------------------------------------MGSHAEV--
-ENLDEDGYTQLDFHYQGITGR-------------------RVVLEKV------TCAT--
---SPRWRSIALTLGILCLLKLVIAV--ILGTM---AIWKSN----------S-------
----------------------GSNPLKNDTFPSRNKE------NHSLPTQSSLED----
------------------------------------------------------------
---------HVTP-TKSLRT---------------T-GD---F

PF05473 // ENSGT00700000104266_Domain_2 (344, 531)

SSSCPPNWIIHKNNCYL
FSTS---LTSWNRSKSQCSQLYSNLLKIDSAEEL-------------------EFVVRHM
SSQ---PDNSFWIGLS-RHQTE--GPWLWEDG----S---VFSSNLFQ---------IRS
TETQESSSHSCVWIHLSIIY--------------DQLCSVPSY---SICEKKLSIK----
--------------------------------------------------------

------------------------------------------------------------
--------MT-------VDDHKS----MRDQLDQ-------KPNGERAK---GLHFVS--
---SRKWYPAAVTLGVLCLGLLVTVI--LLILQLSQVSDLLKQQQANITHQENILEGQIL
AQRQSEKSS--QESQEELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAAN-----
------------------------------------------------------------
------------------------------------------YSGPCPQDWLWHEENCYQ
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQENCLSLDAHLLKINSTDEL-------------------EFIQQMI
A----HSSFPFWTGLS-MRKPS--YSWLWEDG----T---PLMPHLFR---------IQG
AVSHMYPSGTCAYIQRRTVF--------------AENCILTAF---SICQKKANILR-AQ
--------------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVRSNWDGNNLRKG--------E------HVAQ--
---SSIWRGAALSLMTLCLLLVAGLV--TLGIIFLQMSND----------ITS-------
---DSEKLNQLQKIIHPQQDNLSEPLNISRNGPSEE-YLQSQISALLERQEQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHT-------------------SDHKCNPCPKSWQWHGNSCYY
FTIH--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWSDSRKDCTDKNATLVKIDSFRER-------------------NFL----
QSQPSLPLSFFWLGLSWNSTG---RHWVWEDG----S---TPSPTLFSYQEQ---ARF--
-----NGSRGCAYFERGNVY--------------ISRCSAEIS---WICEKTASLVK-IE
DLV-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDNPTSE-----------TSQ------------KC-------LT--S
TKLSGTCCVVMAISWIFCIGLLTTSI--FLGIKFFQVSTISMQQQEKLIHQERALLNF--
--------T-------QWKKNHDL-----------------QMKYCQTLMQNSFSL-A--
------------------------------------------------------------
-----------------------------------------CDCSPCPENWIQNGKSCYY
VSDI---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KSWPASKEACLKEGSSLLQIDNEEEM-------------------VFITKNL
QKL--KAGYEYWVEIS-QDGLQ--APLLWQDG----S---SPSPDLLPT-----------
-KRPQSTNQLCRFLKDNVLS--------------SDNCNNWKY---FICEKCSLRCS-I-
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-D----------TYQ------------KC-------LS--S
NKCSGACCLVMVISCVFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSCAL-----------------QMKYCQAFMQNSLSS-A--
------------------------------------------------------------
-----------------------------------------HNSSPCPNNWIQNRESCYY
VSEI---WSI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--KGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERSQSANQVCGYMKSNSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPQKPAPSS------------------------V------DPAS--
---SSWWRVMSLILLILSLGMVAALV--ALGIMSVT------------------------
------------------QQ-------------N---NLQAEKENLSGTVQNL-AK----
------------------------------------------------------------
---------NFCQ-HIIQQL----------EENQK--RSADHKCSPCDTNWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKRYCSNRNATLTKTASKNIL-------------------DYI----
KDRT---VFIRWVGLS-RQNAD--KVWMWDDG----S---VLSKNM----LE-----F--
-FEDGGENMDCAYFHKGKIY--------------PTFCKNRHY---LMCERKAGMTN-VD
QLL-----------------------------------------------------

------------------------------------------------------------
---------------------------------------------------------LAF
SSVKSHWRSVAISLGIFCLVLLGTAG--TLGFMVMQASQRVS----------S-------
----------------------QN------------------------------------
------------------------------------------------------------
---------------ENLTL---------------QKGR---QCSPCPEKWLQRGDNCYF
FSTK---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 461)

NTWEEGKSQCITLNSRFLKIESKEEL-------------------EFILES-
-AQ---SYNSYWIGLF-RSRAG--GPWLWDDN----S---TFITDL--------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DSAS--
---SSWWRVMALILMILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGA--V-KGHKCSPCDTNWRYYGDNCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

-------------------------------------------------MQAKFSSTR--
-DMLDDDGDTTISLYSRASAATR-------RS--------EP-------GHTEH-RTP--
---SPAWRPVGLTLLTLCLVLLIGLA--VLGFLFFQFYQLSNTQQDTISQKEE-------
---------------------------RLGNLSRQLQSLQAQNRKLAETLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

SRSWQGCEHFCIAENSTMLKISTQEML-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSD--KAWLWMDG----S---PYSLELFDI--IIDVT----
----IPRSRDCVTILNGKAF--------------SKDCRELRR---CACERRAALVK-PE
RVL-----------------------------------------------------

---------------------------------------------------MAYRSEL--
-ENLDEDGYTQLQFSSRGINKR-------------------PVSSEKG------PCAA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 153)

SLPWRSIAVTLGILCLVILVIAI--VLGT

ENSGT00700000104266_Linker_0_2 (153, 367)

M---GIWRSN----------S-------
----------------------GSNSLKNDNFPSR------------KPTQSSLEE----
------------------------------------------------------------
---------SVDS-PKALTT---------------T----RVLSSSCPPNWIAHEKSCYL
FGTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LNSWNESKRQCSQLDSYLLKIDSSKEL-------------------EFIERDK
FSY---PFSEKLAGLE-GGGAM--GGWLWENTDHQGA---APVFNRFE---------IRS
TVTQENSSHNCVWIHVSIIY--------------DQLCSMPSY---GICEKKLSM-----
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYMTLNIETRKPTLTS------------------------V------DPAS--
---SSLWRVMALILLVLCAAMVVGLV--ALGIMSVT------------------------
------------------QQ-------------N---YLQAENENLSRTLQQL-AK----
------------------------------------------------------------
---------KFCQ-NLIRQL----------EKKDN----LSHKCSPCDTNWRYYGDNCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWEDSKWYCIDQNATLVKIANQSIL-------------------EYI----
KSRT---SLIRWVGLS-RQNSN--NMWLWEDG----S---VPSENV----FE-----H--
-SGNEGENMDCAYFHSGKIH--------------PTFCKNKYY---LMCERKAGLAK-VD
ELL-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPSLIS------------------------V------GHAS--
---SSWWRVMALILLILCVGMVIGLV--ALGIWSAV------------------------
------------------QQ-------------N---YLQDENENLSAALQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQA----------EQKGT--F-KDHKCSPCDTNWRYYGGSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCIDMNSTLLKIDNQNVQ-------------------EYI----
KART---RLIRWVGLS-RQKSD--EVWKWEDG----S---VLSQNM----FE-----L--
-LEDGKENMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGKAN-VD
QLP-----------------------------------------------------

-------------------------------------------------MLAKYNSTR--
-DMLDDD-DTTISLYSRAS---R-------QP--------EP-------RHSEN-GTP--
---SSVWRPVALTLLTLCLVLLIGLA--ALGLVFFQFYQLSNIQQDNISEKDE-------
---------------------------KLGNFSRQLQLLQIQNRKIAETLQHVAV-----
------------------------------------------------------------
---------KLCR-EMYNKS-------------------GGHRCSPCPENWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKNWQSCEYFCLAENATMLKISSQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWMDG----T---PYSFELFEI--IIDPT----
----NIRNRDCMTIFNGKAY--------------SKDCKELRR---CACERMAGRVV-PE
QLY-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRDGNNLRKR--------G------HPAP--
---SP

PF08391 // ENSGT00700000104266_Domain_2 (126, 361)

MWRHTALGLLTLCLVLLIGLV--TLGIMFLQISNE----------INS-------
---GSEILSQLQKTVDQQQDNLSQQLGNSNNLSTEEEFLKSRISSLLNRLEQMAV-----
------------------------------------------------------------
---------KLCQ-ELITHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--EEKTWTNSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLRFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKRCAYFQKGNIH--------------ISRCSAEIF---WICEKTAVPVK-TE
DL------------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRSN----------S-------
----------------------GSNTLENGYFPSRNKE------NHSQPTQSSLED----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-EV---LSSPCPPNWIIYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLLKIDSSNEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPDCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
--MLDEDGYITLNVKNRKPALTS------------------------V------DPAS--
---SPLWRVTALILLILCMGLAVGLV--ALGVMSIT------------------------
------------------EQ-------------N---YQQAENKNASGTLHQL-AK----
------------------------------------------------------------
---------KFCQ-NLIKQL----------EQKNI----VSHKCSPCDRNWRYYGDSCYG
FFRH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NLTWEEGKQFCISMNSTLLKVASQSVL-------------------EYM----
KSRT---GLIRWVGLS-RKNPN--EVWMWEDG----S---VPSKNV----FE-----L--
-SGNERENMNCAYFYDGKIY--------------PTFCKNKHY---LTCERKAGMVN-VD
TLL-----------------------------------------------------

------------------------------------------------------------
--MQEEETYASLQWDNPTPS-----------PYQ------------KH-------LS--S
TKFSGSWCLVMVISCILCVGSVTTSI--FLGIKLFQVSTIAIKQQEKLIHQDIALLNF--
--------T-------RWKKNYNL-----------------QMKYCQTLMQNSFSS-VTI
QSSILCFIQS-------------LKLIGV-------------------------------
-SLI--------------------------------IVLNSSICNPCPENWIQNGGSCYR
VFEN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WKFWNTSKEDCLKEGSNLLQIDSKEEM-------------------DFITGIL
RKV--QRGYDYWVGLS-QDGLS--RPWLWEDG----S---SPSPDLLPI-----------
-QTFQSTDQLCGYLKDKLLS--------------SANCNIWKY---FICEKYALRSS-I-
--------------------------------------------------------

-----------------------------------------M-SIQGLSRTMEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCVA--
---SPPWRLIAVILGILCLVILVIAV--VLGTMGYEAIWRPN----------S-------
----------------------GRNSLENGYFPSRNKE------NHSQPTQSPLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---L

PF05473 // ENSGT00700000104266_Domain_2 (344, 531)

SSPCPPNWIIYEKSCYL
FSPS---LNSWDGSKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFPSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSLPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
------MTSD-------DPKTKS----TKDCPVG-------RSDAERA---KGLAFLS--
---SPWWFPVAMTLGVICLGLLVTII--VLETRLFQVSNLLKQYGGNLTQQENVLQGQIL
AQRQAENAS--QMSQRELRDAIETLSQQLHEKSQKQMELHQHNLHLQEALQKVANFS---
------------------------------------------------------------
--------------------------------------------GPCPQGWIWHGEDCYA
FSSG---P

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LDWGKSRENCLLLNAQLLKINSTDDL-------------------DFIQRAI
A----HSSSPFWVGLS-LRKPN--RSWLWEDG----S---PLKPRLFR---------LQG
GSSQT-HSRTCAYLQQGVVF--------------AENCILAAF---SICQKKADLWR-SQ
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------PCPQDWFWHGESCYI
FSSH---F

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

KNWKMSQENCASQGSQLLKVDDQDEL-------------------EFVYRAM
A----HSRNPFWLGLR-RSDAR--SRWVWEDG----S---TPFVGLLQ---------AWR
YLSHTYSSGTCGCIFQGNII--------------AESCIITAS---SICERKANL-----
--------------------------------------------------------

---------------------------------------------------MESHPDF--
-ENVDEDGYTKLNFNTQDATRS-------------------PV----G------LSGI--
PAASPAWRLIAVILGILCLIILVIAV--VLGSL---AFWRSN----------S-------
----------------------GSNLLEKDNSLSRNKE------YQNQPTKSSLQE----
------------------------------------------------------------
---------NAAS-TKAFKT---------------T-GV---FSSTCPPNWIAHEKSCYL
FSIS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWYGSKRRCSQLGSHLLKIDTLKEF-------------------DFIVGQM
SSY---PNNSFWIGLS-RNQTE--SLWYYFGCDNYIT---VFYFNSLQ---------IRS
TATQENTPHNCVWLHVGNAY--------------DQPCNILSF---SVCERLL-------
--------------------------------------------------------

---------------------------------------------------MKYHSHP--
-ENLDEDGYTQLDFRTRGIHKR-------------------PEGSEKG------SQAS--
---SPPWRPIVVALGILCLVALVVAS--VLGVL---GEYGFN----------S-------
----------------------GRNPEEKENFPSRNKE------NH-KPTKSSLDE----
------------------------------------------------------------
---------KLAP-SKASQT---------------T-EH---FSGPCPPNWVIHEKSCYL
FKMS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

RNSWAGSKRHCSQLGAHLLKIDNSKEF-------------------EFIESQT
SSH---HINSFWIGLS-RNQTE--GPWFWEDG----S---PFIPNSFQ---------VRD
TASKESLLHNCVWIHGSEVF--------------NQICNISTF---SICEKQL-------
--------------------------------------------------------

---------------------------------------------------MEYHSHL--
-ENLDEDGYTQLDFRTQGIHKR-------------------PVGSEKG------SQVP--
---SPPWRLIVTALGILCLVAIVVAT--VLGVL---GEYGFN----------S-------
----------------------GRNPEEKENFPSRNKE------NH-KPTKSSLDE----
------------------------------------------------------------
---------KVAP-SKASQT---------------T-GL---SSGPCPPNWIIHEKSCYL
FKMS---ID

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWAGSKRHCSQLGAHLLKIDNSKEF-------------------EFIESQT
SSQ---RMNSFWIGLS-RRQTE--GPWLWEDG----S---QFIPNLFQ---------VRD
TASQESLLHNCVWIHGSEVY--------------NQICNISSF---SICEKQL-------
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------VT------------------------
------------------QQ-------------N---LQKAENGNLSETLNQL-AK----
------------------------------------------------------------
---------YFCQ-DLIKQS----------EQKGI--H-KDHQCSPCDTNWRYYGNSCYG
FFKH--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-NLTWDESKQYCSEMKAKLVKIASQEIL-------------------KYI----
KGRT---GLIRWVGLS-RQNSD--GVWMWEDG----S---VFSKNM----IT-----L--
-SGDARENMNCAYFYNGKIV--------------PSSCESKQY---LMCERKAGVAK-VA
ELLQ----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDNPASK-----------ASQ------------KC-------LT--P
IKYSGTWCVVTVISCVFCVALLATSI--FLGIKFFQVSALAMKQQEMLIQQDKALQNF--
--------T-------QWQGNHTL-----------------QMKHCQAVVQSSPQS----
------------------------------------------------------------
----------------------------------------GNNCSPCPQNWIQNGESCYY
VFES---WRI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WNNGKEGCLMEDSSLLQIDSKEEM-------------------SFITYSL
QKF--KGGFDYWVGMS-QDGLG--GPWLWQNG----S---SPPSDLLPT-----------
-ERHQSTNQLCGYLKNHSLF--------------SANCNASKY---FICEKNAFKSC-I-
--------------------------------------------------------

-----------------------------------------------MNEWID--GWI--
-NKSNEGVYH-------LLLFVNF-----------ALI-----FLSTA------PPPP--
---SHVWRHTALFLTLLCLLLLVGLG--VLGSKFY----------RT---LKI-------
---DMEKLDKLQNMNEELQRNVSLQLMNNISSSN-------KIRNFSITLQKIAT-----
------------------------------------------------------------
---------KLCY-ELYRKE-------------------QEHKCKPCPKKWLWHEDNCYL
PYDN---I

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQKSEKQCASQNARLLKINSKSAL-------------------DFI----
KSR---DLYDYWLGLS-PREDY--IYF-KLDE----I---VNSPDW----EIRNTTDF-N
N-------KYCGYLSGQYVY--------------YYKCDIRKK---IICEKMANPVK-IE
SALASEVPD-----------------------------------------------

------------------------------------------------------------
--MSDQVSYA-------TLTFQDPAGARNNQDGNNLRKR--------G------HLAP--
---AHLWRRAALGTLVLCLLLLTGLV--TAGVMVLQMSKE----------INS-------
---DSEQLKWLQETFHQKQDNLSEQLSNCRKAPTGEEFLKAQIAELLQRQQEMAT-----
------------------------------------------------------------
---------ELCK-DLVTHK-------------------SDHKCNPCPKTWQWYQHSCYH
FTTG--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKAWGDSRKDCADQNATLVKIDSMKEK-------------------DFL----
QSQPLSSLAFFWLGLSRNPSHH--QSWLWEDG----S---MPSPSILSDKER---TQM--
-----NGSQGCAYFQRGNIY--------------VSRCSAEIS---WICEKTAPLVK-IE
DLY-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLRFQGSNKTENTQE---FDE-----LKKKA------AATP--
---SHVWRHAVLPLGFLCLLLFIGMG--VLGVFFI----------LLLNKVKI-------
---EKEKFGKLQNINEELERNVSLQLMNNTSSSN-------ELRNLSNTLQKIAT-----
------------------------------------------------------------
---------KLCY-ELYRQK-------------------SEHKCKPCPTRWLWHEKSCYL
LDQE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

ERTWQDSKTACAAQNASLLKINNKSAL-------------------DFI----
KPW---KLYDYWLGLS-PETENTKPHFKKLDD----I---LNSSACFSFRIIENINDL-N
N-------MYCGYMHGTYVY--------------YRACGYKSK---AICQKMANPVK-IE
STL-----------------------------------------------------

------------------------------------------------------------
--MQDEDLYTSLQWDTPTPH-----------PSQ------------KH-------QS--S
TKCSGTWCLMMVISCIFCVGSLTASI--FLGIKFFQVSAIAKKQQEKLMQQDRALLNF--
--------T-------QWQKNHGL-----------------QIKYCQTLMQNFSRS-DTD
HQGADAQCRS-------------CPLVVS-------------------------------
-TLP--------------------------------LGELGSATTPCPDNWIQNGKSCYH
VFES--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WNNWETSKEDCLKEGSSLLQIDSKEEM-------------------EFITDSL
RKI--KSAHDYWVGLS-QDGPS--QPWFWQDG----S---TPSPDLLPT-----------
-KRPQSTHQLCGYFRNKVLS--------------SANCTVWKY---FICEKYTLRSP-D-
--------------------------------------------------------

-----------------------------------------------------LFAYS--
-SMSEEITYA-------DLKFQDSCKTEHIQV---LDK-----FGKKA------PPAP--
---SHTWHLATVALILICLLLLIGLG--TLGSLFG----------IT---LKT-------
---EVEKVNKLQNINEELQKNVSLQLMNNMNSSN-------KIRNLSIVLQKIAT-----
------------------------------------------------------------
---------NLCY-ELYRKN-------------------PEHKCIPCPNGWRWHEVSCYL
LSDD---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQESKMMCAAQNASLLKINNMSEL-------------------QFI----
KSQ---LLYDYWLGSP-LKTKR--TYAEKLDD----I---INFSTW----DLREINDL-N
K-------TYCGYIYGTYVY--------------YTPCTNNKK---MLCEKIVNPVK-IE
STLMSEVSD-----------------------------------------------

------------------------------------------------------------
------MTFD-------DLNIKT----MRDHPDE-------KSNGRKA---KGLPFLY--
---SPWWCLVAVTLGVLCLGSVVIII--KLGVELSQVSDLLTQQQVNLTHQKNKLERQIS
ARQQAEEAS--QESQKELKEIIETLAQKLNEKSKEQMELHQQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHKENCYL
FPSG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LDWKKSQENCLSLDAKLLKINSTEDL-------------------DFILQAI
S----HSSFPFWTGLS-RRNPR--YPWLWEDG----S---PLMPYLFR---------LRG
AISQTYSLGTCAYIQQGAVF--------------AENCALVAF---RICQKEANLLR-AQ
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTVVSVHSRASSPSQ-------QP--------EA-------GRKGH-RPP--
---SSVWRPVALTLLTLCLVLLLGLL--ALGLVFFQFYQLSNTQQDSISDKEE-------
---------------------------RLANLSRQLQSLQTKNRKLAEILQRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEKWKWHGDKCYR
FCRD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCIAENATMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSR--QAWLWTDG----T---PYSSELFEI--RIDFT----
----SLRSRDCVTILNGKAF--------------SKDCKELRR---CACERRAAAVK-PE
SLH-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGASTVTR-------RA--------EP-------RHSEN-ETP--
---SSVWRPVALTLLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDSIAEQEE-------
---------------------------RLGNLSRQLQSLQSQNRRLVDTLQNVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCLTDNATMLKIITQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERLAGV-V-PE
VLQQ----------------------------------------------------

------------------------------------------------------------
--MQDEDGYVILNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPALVS------------------------V------GPAS--
---SSWWRVTALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWQESKQYCTDMNATLLKIDNQNIV-------------------EYI----
KART---SLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEGGKGNMNCAYFRNGKMY--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
------MTFD-------D-KMKP----ANDQPDQ-------KSYGRKP---KGLCLLS--
---SPWWFPAAMTLVILCLVLSVTLI--VQWTQLLQVSDLLKQYQANLTQQDHVLEGQML
AQQKAENAS--QESKKELKGKIDTLTQKLNKKSKEQEELLQKNQNLQEALQRAANSSEES
LREHKGKI-DTLTWKLNEKSKEQEELLQKIQDLQEALQRAANSSEESLREH---------
----KGKIDTLTW-KLNEKSKEQEELLQKIQDLQEALQ-----RGPCPQDWLWHKENCYL
FHGP----F

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWEKSREICLSLGAQLLQISSADDL-------------------TFILQAI
S----HSTSPFWMGLH-RKKPD--HPWLWENG----T---PLSFQFFR---------TRG
ISLQLYSSGNCAYLQDRVVF--------------AENCILTAF---SICQKKANLLQ-I-
--------------------------------------------------------

-------------------------------------------------MQTKYSSERDV
RGMLDEDGDTTMSLHSRASTVSR-------QP--------ET-------RHTEP-RTA--
---LSAWRPVALTLLTLCLVLLAGLA--ALGLGFFQFYQLSSVQQAIISENEE-------
---------------------------RLGNLSQQLQSLQVKNKKLAETLQRVAE-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGPRCSPCPGKWKWHGDKCYQ
FYQA---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCNAENSTMLKIDTQEVL-------------------DFSMLQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----A---PYSFELFEI--IIDAS----
----SVRSRDCVTILNGKAF--------------SKDCRELRR---CACERVAGRVD-PE
KLQ-----------------------------------------------------

-------------------------------------------------MQAKYNSTL--
-DMLDDDGETTLSLRSQALTIAP-------RP--------ES-------KNSGY-PTT--
---SPTWRPVALILLTLCLLLLIGLG--VLGLEFFQIIQLSNTQKDILTQKEE-------
---------------------------KLGNFSRQLHSLQTQNRKLTDTLQHLAK-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPKKWKWHKDNCYC
FFKE---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

SNTWQGCEHFCTAENSTLLKIETQDVL-------------------EFVMPHS
YSQF---FYSYWTGLS-RNGTG--NPWLWMDG----S---LHSSNLFDI--VVDLS----
----SLRSWDCVTILNGRAF--------------SKDCMELRR---CACQRMAAMVM-PE
WLE-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNFKSRASAGTSRL---------------------TV------KPAV--
---SPAWRPVALSLLFLCLGMAVGLV--TLGIMLFIQQDYLHI-----------------
-----------------------------------------ENGNLSEILQQV-AK----
------------------------------------------------------------
---------NFCN-ELIQK-------------------TVGHKCNPCDTNWRYHGDRCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWAESKEYCAERNATLVMILNKDIL-------------------DFV----
KGRT---SFIRWIGLS-RQKSD--GIWIWEDG----S---ALSKNV----FE-----L--
-LGNGRNDQQCAYFHKGKIY--------------TSLCEDTHY---LICEQKANPVR-ID
QLI-----------------------------------------------------

---------------------------------------------------MEYHPGL--
-ENLDEDGYTQLDFNSRGITRK-------------------PVFSEKG------ICSS--
---SPCWRAIAVTLGILCLVILGIVV--VLGTS---VTWRSN----------S-------
----------------------ESNSLEKGNFTSRNKE------THSPTTQESLF-----
------------------------------------------------------------
------------P-TKTPTA-------------------PGIFSSPCAPNWIMREKSCYL
FGTS---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EQSWNNSKTKCSQEGSTLLKIDSPKEL-------------------EFIERQM
SSQ---PHASFWIGLS-RASAK--GPWLWEDG----S---LFSSNLFQ---------IRS
TDTQGRSSHNCVWIHASIIY--------------DQLCSVPSY---SICEKKLST-----
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYSSLQWDSPPSE-----------AAQ------------KC-------LS--S
SKCSGICCVTTVISCVFCVGLLATSI--FLGIKFFQVSSLAMSQQERLIQQDRALQNL--
--------T-------EWQRNYAL-----------------QMKNCQALQQRSPPS----
------------------------------------------------------------
----------------------------------------GSNCSPCPHNWIQNGQSCYY
VSQI---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWNGSKENCSKEGARLLQIDSKEEM-------------------DFIVCSL
WKL--RRGVEYWVGVY-QEGLS--RSWIWQDG----S---SPPSDWLPT-----------
-ESQSSVSQTCGYLKDRSLF--------------SANCSSRRY---FICEKNVFRSC-I-
--------------------------------------------------------

------------------------------------------------------------
------MTFN-------G-KMTP----VNEQPDE-------KSYHKKA---KGLHFLS--
---SPWWCPAAMTLVILCLGLSVTLI--IQRMQFLQVSNLLKQYQANLTHQEHILEGQIL
AQQQAANTS--Q---K--------------------------------------------
-------------------------------------------------KL---------
----KEMIDTLTW-ELKEKSKEQEGLLQQNLDLQQALQRAENFTGPCPQDWLWHKENCYL
FSSE---Q

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

SYWAKSQEICLSLDAQLLQINSIDDL-------------------NFISQTT
S----HSTSPFWMGLR-RKKQN--DPWLWENG----S---PLRPHLFT---------IRG
IPPQTHPSGTCVYIQEGVVF--------------ADNCILTAF---SLCQKRAKLLL-MQ
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSP-VPN--------TY--Q------------KC-------LP--S
SKCSGTRCLVMVISCIFCMGLLTTSI--FLAIKLLQVSTIVIQQQEKLIQQERALLNC--
--------T-------QWNRSHAL-----------------QMKYYQTFMQNFLSS-A--
------------------------------------------------------------
-----------------------------------------RNCKPCPDNWIQNGESCYY
VSEK---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

YWHTSQKNCLKEGSMLLQIDSKEEM-------------------DFITGSL
RTI--EGGHEYWVGLS-QNGHS--GHWLWQDG----S---SPSPGLLPV-----------
-ERSQSTKQVCGYVKNHSLL--------------SSNCSSWKH---FICEKHALRPS-I-
--------------------------------------------------------

-------------------------------------------------VWIDFFTYS--
-SMSEEVTYA-------DLKFQNSSETEKIQE---IAK-----FGEKA------PPAP--
---SCVWRPAALFLTVLCLLMLIGLG--VLGSMFH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSQS--TSYPYWLGLS-PEKDY--SYGTSVDD----I---INSSAW----VTRNASDL-N
N-------MFCGYINRIYVH--------------YDYCIYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQNSSETEKIQE---IAK-----FGEK-------------
---------------------------------VH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNMNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSDD---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWQESRMACAAQNASLLKINNKNAL-------------------EFI----
KSRS--TSYPYWLGLS-PEKDY--SYGTSVDD----I---INSSAW----VTRNASDL-N
N-------MFCGYINRIYVH--------------YDYCIYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSVAAG-NRDTNNLRKR--------G------HPAS--
---SSIWRQAALGLLTFCLMLLIGLV--TLGIMFLQTSNE----------INS-------
---DSEKLSQLQKIIHQQQDNLSQQLSYYRNFPTEEE-LKSQISNLLKRQRQMAV-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHKCKPCPKTWHWHRNSCYY
FATN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWPNSRKSCMDKNSTLVKIDSLEEK-------------------VFL----
KSQPLPKFSFFWLGLSWDPSG---QRWLWEDG----T---LLSPSLLSTNEY---AQM--
-----NRSRGCAYFQKGSIY--------------VSRCSAETS---WICEKTAASVT-IE
DLD-----------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLTFQDSSGARNNQDGNNLRKR--------G------HPAP--
---SPIWRQAAQGLLTLCLMLLIGLV--TLGIMFLQMSNK----------INS-------
---DSETLNRLQKIIHHQQENLSQQLSNHRNLPMEEEFLKSQISNLLKRQGQIAI-----
------------------------------------------------------------
---------KLCR-ELIIHT-------------------SDHKCNPCPKTWQWYQESCYY
FTIN--K

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWSNSREDCIEKNSTLLKIDSLEEK-------------------NFL----
TSQPLPMISFFWLGLSWHPSD---GNWLWEDG----S---VPSPYLFSNNEL---SQI--
-----NGSKGCAYFQRGNIY--------------VSRCSAEIS---WICEKTAKLVK-IE
DLY-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDGDTTMSLHSQGSATTR-------HP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--ALGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNTSQELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCTEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------EFAASQS
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFTSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCKELKR---CVCERRAGMVK-PE
SLHVPPETLGEGD-------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQNSSEMENIQE---FDQ-----VGVKA------PPAP--
---SHVWRRRALALILLCLLLLIGLG--VLGSIFY----------LT---LKI-------
---EMEKLEKLQNFKDKLQSNVSLQLIHNMDSLE-------KIRNLSNTLQEMAT-----
------------------------------------------------------------
---------KLCY-ELCRKE-------------------PEHKCKPCPEKWEWHEDSCYR
EFKA--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SETWQQSDSTCSAHNASLVKIKNKSVS-------------------EFI----
KSKE---LYGYWLGLS-PRKDK--KTQNILDE----T---IISSDW----FTGNTSDLNG
V-------MYCGYIQYTYVY--------------YGLCTWRKN---AICEKLANPVK-IE
SILMNEEPSERM--------------------------------------------

---------------------------------------------------MECHSSL--
-ENVDEDGYTQLNFHSRVTNRT-------------------HVLPQKG------TQRT--
--APP

PF08391 // ENSGT00700000104266_Domain_0 (126, 161)

SWRLIAVILGVLCLVILVVAV--VLAAL-T--FQR

ENSGT00700000104266_Linker_0_2 (161, 367)

SN----------S-------
----------------------GSQPLENDNFPSRNKE------NHNQPTKSSLEE----
------------------------------------------------------------
---------KVAP-TKALKT---------------T-GF---FPSSCPPNWIMHETSCYL
FSTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LDSWNESRRRCSQLDSNLLKMDSSKEL-------------------GFINREV
SSQ---AAHSFWIGLS-RSQSE--EPWLWEDG----S---MFSPHIFE---------VRS
TATQENSSHNCAWIHMSVVY--------------DQLCHVPSY---SICEKKLSL-----
--------------------------------------------------------

------------------------------------------------------------
--------MT-------VDDPKG----MKDQLDQ-------KPNGKTAKGTTG--FVS--
---SWRWYPAAVTLGVLCLGLLVTVI--LLILQLSQVSDLIKKQQANITHQEDILEGQIL
AQRRSEKSA--QESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAAN-----
------------------------------------------------------------
------------------------------------------Y

PF05473 // ENSGT00700000104266_Domain_2 (344, 533)

SGPCPQDWLWHEENCYQ
FSSG---SFNWEKSQENCLSLDAHLLKINSTDEL-------------------EFIQQTI
A----HSSFPFWMGLS-MRKPN--YSWLWEDG----T---PLTPHLFR---------IQG
AVSRMYPSGTCAYIQRGTVF--------------AENCILTAF---SICQKKANLLR-AQ
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKAQKPALT------------------------SV------EPAS--
---SPLWRVMALALLVLCVGMVVGLV--ALGLM---------------------------
---------------SVMQQ-------------N---YLQAENENLSGTLKML-VK----
------------------------------------------------------------
---------KVCQ-DLIQLS----------GQK-E-----SHKCNPCDTHWRYYGDSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWEESKKYCIDVNATLVKITSKSIL-------------------QYL----
NSRT---GLIRWIGLS-RQKSS--DVWRWEDG----S---VPSKTV----LK-----L--
-SGTGTENMNCAYFHNGKIH--------------PTFCENRHY---LMCERKAGIVK-VE
QLL-----------------------------------------------------

-----------------MFSQGREKVANFSSCINLFLTTKGEFVSASHVDCLIHQSIP--
-DMQEDETYTSLQWDTPTSN-----------PYQ------------RH-------LS--S
TKNSGVWCLVTVILCIFCIGSLATSI--FLGIKLFQMSTTIMQQQEKLTQQERALLNF--
--------S-------QWKRNPNL-----------------QMTYCQTLMQKSFS-----
------------------------------------------------------------
---------------------------------------SAYNCSPCPNNWIQNGESCYY
VFES---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KFWHTSREDCWKKGSDLLQIESKEEM-------------------DFITGSL
KKI--KRNYDYWVGLS-QNGSN--QPWLWQDG----S---SPSADLLPR-----------
-QGPQPTDQACGYLRDNDLS--------------SANCSVWKY---FICEKYALRSS-T-
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSTG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKAT------
--------------------------------------------------------

-------------------------------------------------MLAKYSSTR--
-DMLDADGDTTMSLHSQASATSQ-------RP--------EL-------GHTEH-QRP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLVFFQFYQLSNTQQDSILQKEE-------
---------------------------KLGNLSRQLQSLRSQNRKLAETLHHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEKWKWHGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWMDG----T---PYSSELFEL--MIDLT----
----SLRSRDCVTILNGKAF--------------SKDCRELRR---CACEKAAATVK-VQ
SLHEPLSRRWR---------------------------------------------

------------------------------------------------------------
--------MT-------VDDHKS----MRDQLDQ-------KPNGETAKGTQGLRFVS--
---SWKWYPAAVTLGVLCLGLLVTVI--LLILQLSQVSDLLKQQQANITHQENILEGQIL
AQRQSEKSS--QESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAAN-----
------------------------------------------------------------
------------------------------------------Y

PF05473 // ENSGT00700000104266_Domain_2 (344, 532)

SGPCPQDWLWHEENCYQ
FSSG---SFNWEKSQENCLSLDAHLLKINSTDEL-------------------EFIQQMI
A----HSSFPFWTGLS-MRKPS--YSWLWEDG----T---PLMPHLFR---------IQG
AVSHMYPSGTCAYIQRRTVF--------------AENCILTAF---SICQKKANILR-AQ
--------------------------------------------------------

-------------------------------------SCPCC-YNNELSRTMEYQSSV--
-ENLDEDGYTQLDFSSRSITRR-------------------SVVSEKG------LCAA--
---SSRWRLIAVTLGILCSVLLVITV--VLSTLVYEGIWRSS----------S-------
-----------------------VELLKSDSFPSRNKD------NQSQPTQSSLED----
------------------------------------------------------------
---------SVIP-TKALTT---------------T-GV---FSSACPPNWITREDSCYL
FNTL---LD

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWDGSKRRCFQLGSNLLKIDSSKEL-------------------EFISRRV
SSQ---PDHSFWIGLS-RRRTE--EPWLWEDG----S---TLLSNLFQ---------IRS
TVTEKDSSHNCAWIHVSDIY--------------NQLCSVHSY---SICEKKLSI-----
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSRKGENIHE---FDT-----VGIKA------PPAP--
---SHGWCQRVLA--LLCLLLLIGLG--VLGSIFY----------TT---LKI-------
---EMRKLNKLQNFKEELQRNISLQLMSNMNSSK-------MIRNLSVTLQVTAT-----
------------------------------------------------------------
---------KLCH-ELYKRE-------------------PEHKCKPCPKTWMWHEDSCYI
LKNS---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

ETWQESVMFCSAQNASLLTIKNKSVL-------------------EFI----
KSNR---LYNYWLGLS--PKYD--RDYQKLDE----T---IFSSNW----FMRNTNDVNG
L-------MYCGYVDIPFVY--------------YIKCTARQR---VICKKLADPVK-IE
SMLMNEIPNEKYS-------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNVKTRKPALIS------------------------V------DSAS--
---SSWWRVMALILMILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGA--F-KGHKCSPCDTNWRYYGDNCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFLNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-D----------TYQ------------KC-------LS--S
NKCSGACCLVMVISCIFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSRVL-----------------QMKYCQAFMQNSLSS-A--
------------------------------------------------------------
-----------------------------------------HNSSPCPNNWIQNRESCYY
VSEI---WSI

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHASQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKI--KGSYDYWVGLS-QDGHS--GRWLWQDG----S---SPSPGLLPV-----------
-ERSQSANQVCGYMKSNSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDDEDTTMSLYSQASATTR-------RP--------EP-------RCTGH-RAP--
---SSAWRPVALILLTLCLVLLIGLA--ALGLLFFQYYQLSNTHQATISHMEE-------
---------------------------RFGNISRQFQSLQVQNTKLAESLQHVAK-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------GAHRCSPCPEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKNWEDCKYFCLSENSTMLKIDTKEEL-------------------EFAMSQS
YSEF---FYFYWMGLF-RPGGG--KVWLWMDG----T---PYTSELFHV--MIDVT----
----SPRSRDCVAILNRMIF--------------SKDCQELKR---CACERRAAMVK-PE
SLRFLPETSGEGD-------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVGSHQDGNNLRRD------DKR------HPAQ--
---FSIWRGAALSLMILCLLLVMGLV--ILGIMFLQMSND----------INS-------
---GAEKLSQLQKIIHPQQNNLSEPLNISTKDPTEE-SLQSQISALLERQGQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHT-------------------SDHKCNPCPKTWQWHGNSCYY
FTNH--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKSWSDSRKDCADKNSTLVKIDSIKER-------------------DFL----
QAQPSLTLSFFWLGLSWNSTG---RHWLWEDG----S---SPSPTLFSDQEH---SRF--
-----NGSRGCAYFERGNVY--------------ISHCSAEIY---WICEKTASLVK-TE
DLDFSKSIKK----------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWKESKQYCTDLNATLLKIDNHNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYVTLNIKTRKPALIS------------------------V------DPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGTLQQL-AK----
------------------------------------------------------------
---------RFCQ-YVIKQS----------ELKGT--F-KGHKCSPCDTNWRYYGDNCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWKESKQYCTDLNATLLKTDNQNIL-------------------EYI----
KART---GLIRWVGLS-RQKSN--EVWKWEDG----S---VLSENM----FE-----L--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSSQTENIQK---FDK-----FEKEE------PPVP--
---SHVWRQRALALTLLCLLLLIGLG--VLGGIC--------------------------
----MEKLNTLRNFKEELQRNMSLQLMQNTNSSQ-------KIRSLSIKLEEIAT-----
------------------------------------------------------------
---------KLCR-ELYIKN-------------------KGNKCKPCPEGWMWHDDNCYL
LLSGYQR

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

RKTWQKSDEICSDYNASLLTIKSKSVL-------------------EFI----
KSLK---LINYWLGLS-PRKDT--TKYNNLD-----T---IISFNW----FTRNTSVISD
E-------MYCGYIYYPSFF--------------YTECTDTKN---IICEKLAQSVK-IE
SILMSEVLDRRK--------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLMFQDSVGERNNLDRNDLRKR--------G------YPAS--
---SPTWRQAALSLLTLCLMLLIGLV--TLGIMFLQTSNE----------INS-------
---DSQKLSQLQKSIHQQQDNLSEQLSIYRNYPTEEEFLKSQIAGLLKRQGQMAV-----
------------------------------------------------------------
---------RLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FATN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEKTWTNSRKNCMDRNSTLVKIDSLEEK-------------------DFL----
KSQPLPTFSFFWLGLSWDPSG---RSWLWEDG----S---GPSPSLFSTKEY---AQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIS---WICEKTAALVK-IE
DLD-----------------------------------------------------

------------------------------------------------------MEYP--
-LDVDEDGYTKLNFHSRGATRR-------------------PVGSKKG------S-----
PVASP

PF08391 // ENSGT00700000104266_Domain_2 (126, 320)

PWKLIAMILGILCLVILVIAV--VLSSL---AFWRSN----------S-------
----------------------RSNPLEKDNSLSRNKE------HQTQPTKSSLEE----
------------------------------------------------------------
---------NVVS-TKALKT---------------T-GA---VPSNCPPNWIVHEKSCYL
LAIS---LDSWYGSKRRCSQLGSHLLKIDTLKEF-------------------DFIVEQM
SSY---AIHSFWIGLS-RNQTE--ELWLWDDGS-------TFSYNLFQ---------ISS
TATQENTAHNCVWIHVGNAY--------------DQPCNIPSF---SMCERLLSG-----
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKMNS---

PF05473 // ENSGT00700000104266_Domain_2 (87, 534)

-MKDQPDQ-------KSFGKKA---KGLRLLS--
---SPCWCPAAITLGILSLGLLVTLI--LLRK----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------QRPCPQDWIWHGENCYL
FSSG---MFNWQKSSKNCSALGAQLLKINNKGDL-------------------VIFLPTF
-----ISD------LR-F------------KQ----G---QVSDGRFK---------LQG
AFPNMYSSDTCAYIQRGDVF--------------RENCILIAT---PICQKSADLL----
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSP-VPD--------TY--Q------------KC-------LS--S
NKCSGTWCLVMVISCIFCLGLLTTSI--FLAIKLLQVSTIVIQQQEKLIQQERALLNC--
--------T-------QWNRSHAL-----------------QMIHCQTFMQNFLSS-A--
------------------------------------------------------------
-----------------------------------------RNCNPCPDNWIQNGESCYY
VSEK---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

YWHTSQENCLKEGSTLLQIDSKEEM-------------------DFITGSL
RKI--EGGHEYWVGLS-QNGHS--GHWLWQDG----S---SLSPSLLPV-----------
-ERSQSTNQVCGYIKNHSLL--------------SSNCSSWKY---FICEKYALRPS-I-
--------------------------------------------------------

-------------------------------------------------MQPKYSSTR--
-DVLDDDGDTTMSLHSQASATAR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--VLGLLFFQYYQLSNTGQGTISQMAE-------
---------------------------RLGNTSRELQSLQVQNRKLSGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GVHRCSPCTDQWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

GKSWEDCKYFCLSENCTMLKINKQEDL-------------------DFAMFQS
RSPF---FYSYWTGLL-RPDSG--KAWMWMDG----T---PFASELFEI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CICERRAGMVK-TE
SLHFPPETLGEGD-------------------------------------------

------------------------------------------------------------
--LSRAAAMQ-------N--------TEGDT-KPNIPRRPSSKGFGNK------DVPV--
---HSVWRLLSLLLLILCLIQLIGLV--GFGIRTSLNHSTYQLSLSNNNNISHIFSAL--
--RFHLLLEW-F---------SSLQKEFL----------LSQNSKLSADLREVTT-----
------------------------------------------------------------
---------KFCR-KLMENK-------------------TDHPCKPCPEHWYWHGNNCYK
IMME---

PF00059 // ENSGT00700000104266_Domain_2 (368, 464)

NLTWSESREACAFQNSSLVKIDNKEEW-------------------YFV----
TAKI---ERYHWVGLS-RNARD--LPLKWEDG----S---EVNSEV--------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLNFQDSGRKKSIQE---FGT-----VGIKA------PAAT--
---SHVWHQRALALILLCLLLLIGLG--ILGSVFY----------IT---LKK-------
---EMRKLNKLQNIKEELQRNVSVQLMHSMNSSQ-------MIRNLSLTLQEIAT-----
------------------------------------------------------------
---------KLCH-ELYQRE-------------------PEHKCKPCPKKWIWHEDSCYL
VTKN---YV

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

TWQKNAMFCSAQNASLLVIKNKSVL-------------------EFV----
KSRN---LRKYWLGLS-PRKYY--ADYKIVDE----T---IFSSDW----FVGNTKDVDD
T-------MFCGYIDTIYVS--------------YTLCSDSKN---IICEKLANPVK-IE
NTLMSEIPYEKYD-------------------------------------------

------------------------------------------------------------
-MSEEEVTYT-------TLVFQDPARSGNYRDRNNLKKR--------G------YQFL--
---SPIWRQTSLVLLVLCLMMLIGLV--TLGXXXLQASNE----------INS-------
---DSEKLSQLQKVLHPGQDNSSQEVNIYRNFPTEEEFLKAQISKLLKRQHQMAI-----
------------------------------------------------------------
---------KLCQ-ELITHK-------------------SDHKCNPCPKAWQWYQDSCYY
FITN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 457)

EEKTWINSREDCLEKNSTLVKIDSMAEK-------------------DFL----
KSQSSPRYSFFWLGLSWDPSC---RSWLWEDG----S---LPSPFLVFNY----------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----VKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLAAATLGVLCLGLVVTIM--VLGMQLSQVSDLLTQEQANLTHQKKKLEGQIS
ARQQAEEAS--QESQNELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHGENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLNAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------VRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPQKPAVSS------------------------A------D--S--
---SSWWRVMALILLILSVGMVVALV--VLGFMSVT------------------------
------------------QQ-------------N---NLQAENENLSGTVQKL-AR----
------------------------------------------------------------
---------NFCQ-YIIQQT----------EEKQK--RSADHKCSPCETNWRYHRDSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEEGKRFCSNWNATLVKIASRSTL-------------------DYF----
KERT---VFIRWVGLS-RQNSD--KVWLWEDG----S---VLSDNV----LD-----F--
-FTDGRENMNCAYFQNGKIH--------------PAFCNNRHY---LMCERKAGMPR-AD
LLL-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLEIKT----MKDQADQ-------KSNGKKA---QGPRLLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 158)

SPCWCPAAVTLGVLCLGLLVTIV--MLGLQLSQA

ENSGT00700000104266_Linker_0_2 (158, 367)

SDLLKRQQVNLTHQENILERQTL
ALQQAEEAS--QESQRKLKKMVETLAQRLDEETKKQMELEHQNLNLKEALKRAAN-----
------------------------------------------------------------
------------------------------------------FSGPCPQDWLWHEENCYL
FSSG--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-PFSWEKSQENCLSLDAHLLKINNTSDL-------------------DFIQQAT
S----HSNFPFWMGLS-LRKPS--SSWLWEDG----S---PWMSHLFS---------LRG
SVSQMFPSGTCAYIQRRAVF--------------AENCILAAF---SICQKRANLLR-VQ
--------------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCAA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRSN----------S-------
----------------------GSNTLENGYFPSRNKE------NHSQPTQSSLED----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSMS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLLKIDSSNEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPDCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
------MTSD-------DFKSKT----MRDQPDQ-------KPNGKKA---KGLHFLS--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 170)

SQWWCPTAVTLGILCLGLLVILI--ILTMQLLQVSDLLKQQQANLT

ENSGT00700000104266_Linker_0_2 (170, 367)

NQEIILEGQIS
AQQQAEQAS--QESERELKETIETLTQKLDENSKKQMELHQQTLNLQEALRKAANFSVRK
KYKGPRKSVYRRRIELLSESR---RQVET---------VASLREIKSMSGPSSTVSQRFQ
AWAIKNINLRLCS-LKNKKQKT----TSKHPSLLSFVMDMLHFLGPCPQDWLWHEENCYL
FSSG--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-PFNWEKSQENCLSLDAQMLKINSTDDL-------------------EFIQQAS
A----HSNFPFWMGLS-LRKPR--SSWLWEDG----S---PLMPHLFR---------LQG
PVSHIYPSGSCAYIQRGAVF--------------ADNCILTAF---SICQKKANLLT-A-
--------------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDIPTSE-----------ASQ------------KC-------PS--L
SKCPGTWCIVTVISCVVCVGLLAASI--FLGIKFSQVSSLVMEQRERLIRQDTALLNL--
--------T-------EWQRNHTL-----------------QLKSCQASLQRSLRS----
------------------------------------------------------------
----------------------------------------GSNCNPCPPNWIQNGKSCYY
AFDR---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

ETWNNSKKSCLKEGDSLLQIDSKEEM-------------------EFINLSI
WKL--KGGYEYWVGVF-QDGPS--GSWFWEDG----S---SPLSDLLPT-----------
-DRQLSASQICGYLKDHTLI--------------SDNCSNWKY---FICEKKAFGSC-I-
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------D-KMKP----VNEQPDQ-------KLCHKKA---KGLRFLS--
---SQWWCPVAMTLVILCVGLLVIVI--IQWMQLLQVSDLLKQYQANLTRQEHTIEGQIL
AQQQTANAS--Q---QKLKETIDTLTWELKEKTKEQEGLLQQNLNLQKALQRAANFSGTE
EGRRLV---SDLLRKYQANLTHQER------ILERQILAQQQAANASQQKL---------
----KETIDTLTW-ELKEKTKDQEELLQQNLNLQKALQKVANFSGPCPQDWLWHKENCYL
FSSA---QS

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

YWAKSQENCRALDAQLLQINSIDNL-------------------NFILQAT
S----HSTSPFWMGLH-RKKKN--DPWLWENG----S---PLRPHLLK---------IRG
IPSQAHPSGTCVYIQEGGIF--------------ADHCILNAF---SICEKQAQLL----
--------------------------------------------------------

------------------------------------------------------------
--MQGDEIYTSLQWDDPSPN-----------YYE------------KP-------LS--P
NKCSGTWCLVTVISCIFCMGSLTASI--FLGIKLFQVSTIAMEQQEKLTQQDRALLNF--
--------T-------QWKGKHDL-----------------LMKCCQALMQKSFSS-A--
------------------------------------------------------------
-----------------------------------------RNCSPCPDNWIWNGESCYY
IFEK--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WQGWRQSKEDCSKEDSKLLQIDTKEEM-------------------DFITRIL
WKT--KKDFHFWVGLS-QEGLS--GPWLWQDG----S---SLSPDLGSI-----------
-QRFQSINEDCGYLRDKSLF--------------SANCSSWKY---FICEKYPVSST-L-
--------------------------------------------------------

------------------------------------------------------------
--MHAEEIYTSLQWDIPTSE-----------ASQ------------KC-------QS--P
SKCSGAWCVVTMISCVVCMGLLATSI--FLGIKFFQVSSLVLEQQERLIQQDTALVNL--
--------T-------QWQRKYTL-----------------E--YCQALLQRSLHS-GTD
ASTGPVLLTS-------------PQMVPQ-------------------------------
TLDSK---------ET------------------------GSDCSPCPHNWIQNGKSCYY
VFER---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

MWNISKKSCLKEGASLFQIDSKEEM-------------------EFIS-SI
GKL--KGGNKYWVGVF-QDGIS--GSWFWEDG----S---SPLSDLLPA-----------
-ERQRSAGQICGYLKDSTLI--------------SDKCDSWKY---FICEKKAFGSC-I-
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKQ---ALS---------------------SA------EP-A--
---SSWWRLTALILLISTMGLVAGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLAEKENLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIRQS----------EIKTK--SSFEHKCSPCATKWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEDSKLFCSEQNATLVKTASQSTL-------------------KYI----
TDRI---TSVRWIGLS-RQNSK--KDWMWEDS----S---VLHNNS----ID-----L--
-SRNTEENMNCAYLHNGKIH--------------PASCTERHY---LICERNAALTR-VE
QLL-----------------------------------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDADGDTMMSLHSRASTATQ-------RP--------EP-------GHTEP-RRP--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 168)

SSAWRPVALILLTLCLVLLISLA--ALGLVFFQFYQLSNTQQEN

ENSGT00700000104266_Linker_0_2 (168, 367)

ISQKEE-------
---------------------------RLGNLSRQLQSLQTQKRKLAETLHHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GEHRCSPCPEKWKWHGDKCYK
FYEE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKSWQGCEYFCIAENSTMLKINTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RNGNG--KAWLWMDG----A---PYSHELFEI--IIDFT----
----SLRSRDCVTILNGKAF--------------SKDCRELRR---CACERAAATVK-LQ
RLREPLAGHGGQW-------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDNQTSH-----------SSQ------------KC-------LS--S
TKISGIWCTLMVISCIFCVGLLTTSI--FLGIKVFQATTTIMKQEEKLIQWDRELLNC--
--------T-------QWEKKYTL-----------------QRKYYQTLLQNVFSS-A--
------------------------------------------------------------
-----------------------------------------HNCGPCPQNWIQNGKSCYH
VFKI---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

KTWDSGKENCLKEGSRLLQIDSKEEM-------------------DFVSGSL
QKV--KASYEYWVGAS-QDGPH--GPWLWQDG----S---TPPPDLFPI-----------
-SRPPSVSQVCRYLRDNSLF--------------SANCTNWKY---FICEKDALRAS-I-
--------------------------------------------------------

------------------------------------------------------------
--MQEDEIYTSLQWDTPTSN-----------PYQ------------KH-------LS--S
TKNSGVWCLVMVILCIFCIGSLATSI--FLGIKLFQMSTTIMKQQEKLIQQERALLNF--
--------T-------QWKRNPNL-----------------QMTYCQTLMQKSLSS-DKF
YKTGETLYQS-------------PKITPQ-------------------------------
GTQN--------------------------------NKQTTYNCSPCPDNWIQNGESCYH
VFES---WTF

PF00059 // ENSGT00700000104266_Domain_2 (371, 531)

WHTSRKDCWKKGSDLLQIESKEEM-------------------DFITGSL
KKI--KRNYDYWVGLS-QNGSN--QPWLWQDG----S---SPSADLLPR-----------
-QGPQSTNQVCGYLRDNDLS--------------SANCSVWKY---FICEKYALRSS-T-
--------------------------------------------------------

---------------------------------------------------MECQSSV--
-ENLDEDGYTQLDFSSRSITRR-------------------SVVSEKG------LCAA--
---SSRWRLIAVTLGILCSVLLVITV--VLSTL---GIWRSS----------S-------
----------------------GNNPLKSDSFPSRNKD------NQSQPTQSSLED----
------------------------------------------------------------
---------SVIP-TKALTT---------------T-GV---FSSACPPNWITREDSCYL
FNTL---LD

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWDGSKRRCFQLGSNLLKIDSSKEL-------------------EFISRRV
SSQ---PDHSFWIGLS-RRRTE--EPWLWEDG----S---TLLSNLFQ---------IRS
TVTEKDSSHNCAWIHVSDIY--------------DQLCSVHSY---SICEKKLSI-----
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------SIFAGSGGLFWVLFQVIQASELIGKQ---EEI-------------L-------
----------------------ANLSLQQRVCSERLQVCQVQIQMSTSPGKDRAGD----
------------------------------------------------------------
---------RSSPKTLYYTL---------------GENDTKSNCSLCLEPWVMNGESCYL
FFDG---W

PF00059 // ENSGT00700000104266_Domain_2 (369, 457)

KNWASSSEFCVQEKSELLKIGSKEEL-------------------AFINRNI
ERKKTGSSWSYWVGLT-QDKCY--GDWRWRDS----T---VPSSDL--------------
------------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDYAGARNNRHGNNLRKK--------G------HPAP--
---SPIWRHAALGLLTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIHQRQDNLSQQLGNSNNLSIEEEFLKSQISSLLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHA-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWTNSRKDCIDKNSTLVKIDTLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-IE
DLD-----------------------------------------------------

---------------------------------------------MSLCPELTQNSSE--
-AMQDEDGYIALNVETRKPTLSSGL---------------------SA------DPAS--
---SSLWRMMALILLILCVGMVIGLV--TLGIVSVT------------------------
------------------QQ-------------N---RLR-QNENVLRTQQQL-VK----
------------------------------------------------------------
---------HFCQ-YLRKQE----------DEG-----SFSHKNISCDTNWRPYGNRCYG
FFKQ---

PF00059 // ENSGT00700000104266_Domain_2 (368, 530)

NLTWEESKQYCTDRNASLLKIANQNIL-------------------EFI----
KSRT---SLTRWVGLS-RQKSS--GIWMWEDG----S---VFCKTP----ID-----L--
-SGSGKENMNCAYFHNGKIH--------------PSFCNNKLY---LMCEQMPGRTK---
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------T-----
PATSP

PF08391 // ENSGT00700000104266_Domain_2 (126, 320)

PWRLIVVILGILCSVILVIAV--VLGSL---GEYLSN----------S-------
----------------------GSNPLKKDNSLSRNKE------YQNQPTKSSLQE----
------------------------------------------------------------
---------NAVS-TKALKT---------------T-GV---FSSTCPPNWIAHEKSCYL
FIIS---QDSWYGSKRRCSQLGSHLVKIDTLKEF-------------------DFIVGEM
SSY---PINSFWIGLS-RNQTD--SLWVWDDGS-------IFSYNLFE---------IRS
TATQEHATHNCVWIHMGNAY--------------DQPCNISSF---SICEKLLS------
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYT-------TLTFRDSVGAGNNQDRHNVRKR--------E------YSAL--
---APIWRWAALSLLTLCLMLLIGLV--TLGVMFLQTSNE----------INS-------
---DSEKLSRLQKTIHQRQDNLSQQLSNYRNLSTEEEFLKSQISDLLKRQGQMAI-----
------------------------------------------------------------
---------RLCQ-ELVIHT-------------------SDHKCNPCPKMWQWYQNSCYS
FATN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

EEETWTNSRKICMNKNSTLVKIDSLEEK-------------------DFL----
KSQLLPQFFFFWLGLSWDPSS---RSWLWEDG----S---IPSPSLFSTKEH---AQI--
-----NGSKGCAYFQKGHIY--------------ISRCSAEIS---WICEKTAALVK-IE
DLV-----------------------------------------------------

------------------------------------------------------------
--MS-TLIPSFTQFQSILVPSV-----LTVFSNS------------VS-------FF--P
VPWLGTWCLVMVISCIFCLGLLTTSI--FLAIKLLQVSTIVIQQQEKLIQQERALLNC--
--------T-------QWNRSYAL-----------------QMKHCQTFMQNFLSS-A--
------------------------------------------------------------
-----------------------------------------HNCNPCPDNWTQNGESCYY
VSEK---WE

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

YWHTSQENCLKEGSTLLQIDSKEEM-------------------DFITGSL
RKI--KGGHEYWVGLS-QNGHS--GHWLWQDG----S---SLSPGLLPV-----------
-ARSQSTNQVCGYIKNNSLL--------------SSNCSSWKY---FICEKYALRLS-I-
--------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----AWCLVVVILCIFCTGSLTTSI--FLGVKLFQVSTVSRKQQEELIQQDRTLLNC--
--------T-------RWNGNHRL-----------------QMKCCQTLTQNSFHS-A--
------------------------------------------------------------
-----------------------------------------HKHGPCPDNWIQNGESCYH
VFEN--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WKVWHASQEACFEECSKLLQIDTKEEM-------------------DFIAGSL
RKT--KSNYDYWVGLS-QAGPS--QPWLWQDG----S----PAPDLSPA-----------
-QGPPSTNRVCGYLKDKILS--------------SANCSSWKY---FICEKYALRST---
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKTRKPALVS------------------------V------GPAS--
---SSWWRVMALILLILCVGMVVGLV--ALGIWSVM------------------------
------------------QH-------------N---YLQDENENRTGALQQL-AK----
------------------------------------------------------------
---------RFCQ-YVVKQS----------ELKGT--F-S-HKCSPCDTNWRYYGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTDMNATLLKIDNRNIV-------------------EYI----
KART---RLIRWVGLS-RQKSN--EVWKWEDG----S---VISENM----FE-----F--
-LEDGKGNMNCAYFHNGKMH--------------PTFCENKHY---LMCERKAGMTK-VD
QLP-----------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIKT----MKDHPDE-------KSNGKKA---KGLPFLY--
---SPWWCPVAVTLGVLCLGSMVIII--KLGMELSQVSDLLTQQQANLTHQKNKLERQIS
ARQQAEETS--QESQKELKEIIETLAQKLNEKSKEQMELHQQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHKENCYL
FSLG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LDWKKSQENCLSLDAKLLKINSTADL-------------------DFILQAV
S----HSSFPFWIGLP-QKNPH--YPWLWEDS----S---PLMPYLFR---------LRG
AISQTYSLGTCAYIQQGAVF--------------AENCALVAF---RICQKKANLLR-AQ
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTTM--VLGMQLSQVSHLLKQQQANLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNSS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

-----------------------------------------------VYSIRTFFKEV--
-SMSEEVTYA-------DLKFPDSLKTENIEA---FEN-----FEIKE------TPVT--
---SDVSHHRVLALTVLCSLLLIGLG--ILGSMFY----------VT---SKK-------
---QMEKLDELQNVNEELQGNLSQLLMDNMNNSM-------KINNLSHTLQEITT-----
------------------------------------------------------------
---------KFCH-ELYRKN-------------------KDHKCKPCPEKWLWHENSCYL
LTTT--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-MKSWQESKMECSAQNASLLKINNKSIS-------------------NYI----
KSK---KLYNFWLGLS-PRYSS--MSDKNLDS----L---IDSPDW----NINKTNKSND
K-------LYCGYLYGYNVY--------------YSHCKTEIY---SICMQLAGPVKI--
--------------------------------------------------------

----------------------------------------------------MEHHSI--
-ENLDEDGYTQLDFSSCNIIRK-------------------PVVSEKG------FCAA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 156)

SPRWRPIAVTLGILCLVMLVITV--VLCT---

ENSGT00700000104266_Linker_0_2 (156, 367)

MAIWRPS----------S-------
----------------------GNNLLKDNSFQSRNKE------NHSQP---SLED----
------------------------------------------------------------
---------NVAP-TKALTT---------------T-GV---LSSSCPPNWITHQNSCYL
FSTS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-LDSWDTSKRRCLQLGSNLLKIDSLNEL-------------------EFISRQV
SSQ---LDHSFWIGLS-RRQTE--EPWLWDDG----S---MLLSNLFQ---------IRR
TVTKQDSSHSCVWIHVSVIY--------------DQLCSVPSY---SICEKKLST-----
--------------------------------------------------------

---------------------------------------------------MEYRSDL--
-ENIDEDGYTRLHFNSQNITRI-------------------PVISNKG------TCAA--
---SPPWRLVAVILGVLCLITLVIAV--VLGTM-------------------S-------
----------------------GSNPLKNDYFPSRNKE------NHSQTTQSSLED----
------------------------------------------------------------
---------SVSP-TKALKT---------------T-GV---LNSPCPPNWIIHENSCYL
FSTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

DSWNGSKKRCSQLDSNLLKIDNSKEL-------------------EFIQRKV
SSL---PDNSFWMGLS-RSRTE--EPWLWEDG----S---TFSSNLFQ---------IRS
TATQENLSPNCVWIHASIIY--------------DQLCSVPSY---SICEKKLSV-----
--------------------------------------------------------

-------------------------------------------------MQAKYSSTK--
-DMLDDDGDTTMSLHSQASATTR-------RP--------EP-------RRTEH-RAP--
---SSTWRPVALTLLTLCLVLLIGLA--ALGLLFFQYYQLSNTGQDTISQMEE-------
---------------------------RLGNMSRELQSLQVQNIKLAGSLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKA-------------------RAHRCSPCTEQWKWHGDNCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWEDCKYFCLSENSTMLKINKQEDL-------------------DFAVSES
YSEF---FYSYWTGLL-RPDSG--KAWLWMDG----T---PFTSELFHI--IIDVT----
----SPRSRDCVAILNGMIF--------------SKDCQELKR---CVCERRAGMVK-PE
SLHFPPETLGEGD-------------------------------------------

-------------------------------------------------MHAKYSSTR--
-DMLDDEWDTTMSLHSQASVTTQ-------QP--------KP-------RHTEH-GAP--
---SSAWRPAALTLLTLCLVLLIGLA--ILGFVFFQYYQLSNSQQDSISQKEE-------
---------------------------RLGNFSQQVQSLQAQNRKLAKTLQHVAE-----
------------------------------------------------------------
---------KLCR-ELYNKT-------------------GGHRCSPCPEKWKWHGDKCYQ
FYKD---

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

SKSWQGCEYFCFAENSTMLKISTQEVL-------------------EFAMPQS
YSEF---FYSYWTGLS-RSGND--KTWLWMDG----S---PYSFELFDI--IIDVT----
----TPRSRDCVTILNGKAF--------------SKDCRELRR---CACERRAAIVN-PE
IKKR----RWVFLIPVPNHQH-----F-----------------------------

-------------------------------------------------MQAKYSSTR--
-DMLDDD-DTTISLYSGTSTVTR-------RA--------EP-------RHSEN-GTP--
---SSVWRPVALTLLTLCLVLLVGLA--ALGLVFFQFYQLSNIQQDSITEKDE-------
---------------------------KLGNMSRQLQSLQAQNRKLIETLQQVAV-----
------------------------------------------------------------
---------KLCR-ELYNKS-------------------GGHRCSPCPEKWKWYGDKCYQ
FYKE--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-SKNWQSCEYFCLADNATMLKISTQEEL-------------------DFAMPQS
YSEF---FYSYWTGLS-RNGSG--KAWLWTDG----T---PYSFELFEI--IIDPT----
----NLRNRDCMTIFNGKAY--------------SKDCKELRR---CACERIAGRVV-PG
ELQ-----------------------------------------------------

------------------------------------------------------------
--MHEEEIYTSLQWDSPAP-N----------TYQ------------KC-------LS--S
NKCSGAWCLVMVISCIFCMGLLTASI--FLGVKLLQVSTIAMQQQEKLIQQERALLNF--
--------T-------EWKRSHVL-----------------QMKFCQTFMQSSFSS-A--
------------------------------------------------------------
-----------------------------------------HNCSPCPNNWIQNRESCYY
VSEH---WK

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

IWHTSQENCLKEGSTLLQIESKEEM-------------------DFITGSL
RKM--RGSYDYWVGLS-QDGHS--GRWLWQDG----S---PPSPGLLPV-----------
-EISQSTNQVCGYIKNSSLL--------------SSNCSTWKY---FICEKYALRSS-V-
--------------------------------------------------------

---------------------------------------------------MAYHSDL--
-ENLDEDGYTQLYFNSQGITRK-------------------TVVLEKG------TRAA--
---SP

PF08391 // ENSGT00700000104266_Domain_0 (126, 210)

PWRLIAVTLGILCLIILVIAV--VLGTMVYEAIWRSN----------S-------
----------------------ENNSLKN

ENSGT00700000104266_Linker_0_2 (210, 369)

DNSLPRHKE------NHSHPTQSSLEE----
------------------------------------------------------------
---------SVAP-TKALKT---------------T-GVPEVPSSSCPPNWIIHEKSCYL
FRTS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

ESWKSSKIQCSQLNSNLLKIDSPKEL-------------------EFIIKQV
SSQ---PNNSFWIGLS-RTQPE--RPWLWEDG----S---TFSSNLFQ---------IRS
TATQENPSSNCVWIHLSIIY--------------DQLCNVSSY---SICEKQLLK-----
--------------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------NLKIQDPDKKEETQK---SDK-----CGGKV------SADA--
---SHSQQKTVLILILLCLLLFIGMG--VLGGIFY----------TT---LAT-------
---EMIKLNQLQSVKEELQENVSLQLKHNLNSSK-------KIKNLSAMLQSTAT-----
------------------------------------------------------------
---------QLCR-ELYSKE-------------------PEHKCKPCPKGSEWYKDSCYS
QLNQ---Y

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

ATWQESVMACSARNASLLKVKNKDVL-------------------EFI----
KYKK---LRYFWLALL-PRKDR--TQYP-LSE----K---MFLSEE----SERSTDDIDK
--------KYCGYIDRVNVY--------------YTYCTDENN---IICEETASKVQ-LE
SVLNGLPEDSR---------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKMAWLSSLSHL---------------------HS------DS-A--
---SSWWRLMALILLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLAEKESLSATLQQL-AK----
------------------------------------------------------------
---------KVCQ-DLIKQS----------ELKTK--NTFEHKCSPCATNWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQFCAEQNATLVKAASQRTV-------------------EYI----
KNRI---TSVRWLGLS-RQNSS--KDWMWEDN----S---VLPKHM----ID-----L--
-SGNTRENMNCAYLYNGKIH--------------PASCTDRHF---LMCERKAGMTR-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKQ---ALS---------------------SA------EP-A--
---SSWWRVMALVLLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------K---YLLAEKENLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIRQS----------EIKTK--STFEHKCSPCATKWRYHGDSCYG
FFRR---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

LTWEESKQYCTEQNATLVKTASQSTL-------------------DYI----
AERI---TSVRWIGLS-RQNSK--KDWMWEDS----S---VLRKNG----IN-----L--
-SGNTEENMNCAYLHNGKIH--------------PASCKERHY---LICERNAGMTR-VD
QLL-----------------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSARVRGNRDGNNLRKE--------G------HPAQ--
---SS

PF08391 // ENSGT00700000104266_Domain_2 (126, 361)

LWRGAALSLMTLCLVLVTGLV--TLATMFLQVSND----------INS-------
---DSEKLSQLQKSIHPQQDNLSESLNSSRKSLTEE-SLQSQISALLERQEQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHA-------------------SDHKCNPCPKTWQWYGNSCYY
FSIN--EEKSWSDSRKDCIDKNATLVKIDSTEER-------------------DLL----
QSQLSLTFSFFWLGLSWNSSG---RNWLWEDG----S---FPPPTLLSDKEL---ASF--
-----NGSRECAYFERGNIY--------------TSRCRAEIP---WICEKRASLVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
------MTFD-------D-KMKP----ANDEPDQ-------KSCGKKP---KGLHLLS--
---SPWWFPAAMTLVILCLVLSVTLI--VQWTQLRQVSDLLKQYQANLTQQDRILEGQML
AQQKAENTS--QESKKELKGKIDTLTQKLNEKSKEQEELLQKNQNLQEALQRAANSSEES
QRELKGKI-DTITRKLDEKSKEQEELLQMIQNLQEALQRAANSSEESQREL---------
----KGKIDTLTL-KLNEKSKEQEELLQKNQNLQEALQRAANFSGPCPQDWLWHKENCYL
FHGP----F

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

SWEKNRQTCQSLGGQLLQINGADDL-------------------TFILQAI
S----HTTSPFWIGLH-RKKPG--QPWLWENG----T---PLNFQFFK---------TRG
VSLQLYSSGNCAYLQDGAVF--------------AENCILIAF---SICQKKTNHLQ-I-
--------------------------------------------------------

---------------------------------------------------MESNSNA--
-ENVDEDGYTQLDFSSRYRARR-------------------PVVSRKG------ISAT--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 158)

SPHWRLIAVTLGSLCLIILVIAV--VLGMT---V

ENSGT00700000104266_Linker_0_2 (158, 367)

FWRSN----------S-------
----------------------GRNLMEDINFPSGSNQ------NHSQPPQSSLEE----
------------------------------------------------------------
---------GVSP-TNVLTT---------------R-GV---YSSPCPPNWIIHEKSCYL
FRKS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-QDSWNSSKKQCSQLDSTLLKIDSAKEL-------------------DFIIKQV
SSQ---PDNSFWIGLS-RSQTK--GPWLWEDG----A---AFPSNLFQ---------IRS
TVTQESLSHNCVWIHMSVIY--------------DQLCSVPSY---SICEKTTAK-----
--------------------------------------------------------

------------------------------------------------------------
--MQDEDGYITLNIKPRKP---TLS---------------------SA------DS-A--
---SSWWRVMALILLISSMGLVVGLV--ALGIMSVT------------------------
------------------QQ-------------R---YPLAEKESLSATLQQL-AK----
------------------------------------------------------------
---------KFCQ-ELIKQS----------ELKTK--NTAEHKCSPCASRWRYHGDSCYG
FFRH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

RTWEESKQYCAEQNATLVKAASQGTV-------------------EYL----
TSRI---TSVRWIGLS-RQNSN--KDWMWEDS----S---VLPKNM----ID-----L--
-SGNPRENMNCAYLYNGKIH--------------PASCEDRHY---LMCERKAGLPR-VD
QLL-----------------------------------------------------

------------------------------------------------------------
------ITFD-------DLKTKT----MKDQADE-------KSNGKKA---KGLQFLS--
---SPCWCPVAVTLGIICLGSLVTIV--MLGVQLSQVSTLLKQQQANLTHQKNTLEGQSL
ARQQGGEAS--EESQRELKEMIETLARKLDEKSKEQMELQHQNMNLQGALRRAANCS---
------------------------------------------------------------
-------------------------------------------

PF05473 // ENSGT00700000104266_Domain_2 (344, 533)

-VPCPQDWIWHGVNCYL
FSSG---PFNWEKSQENCLSLDAQLLKINSTGDL-------------------DFIKQAI
S----HSNFPFWIGLS-LRKPS--NLWLWEDG----S---PLVPHLFR---------LQG
AISQVYPTGTCAYIQRGVVF--------------AENCILAAF---SICQKKANPLT-AQ
--------------------------------------------------------

-----------------------------------------------------FFTYS--
-SMSEEVTYA-------DLKFQNSSETEKVQE---IGK-----FGEKA------PPAP--
---SRVWRPAALFLALLCLLMLIGLG--VLGSTFH----------IT---LKT-------
---AMKKMNKLQNINEELQRNVSLQLMSNTNSSN-------KIRNLSTTLQTIAT-----
------------------------------------------------------------
---------RLCR-ELYSKE-------------------QEHKCKPCPRRWIWHKDSCYF
LSND---V

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QTWQDSRMACAAQNASLLKINNKNAL-------------------EFI----
KSRS--MLYHYWLGLS-PEKDY--SYHMIGDN----I---INSSAW----VIRNAPDL-S
N-------IFCGHINGIYVY--------------YDYCTYRKK---MICEKMANPVQ-LG
FIHFREA-------------------------------------------------

---------------------------------------------MTAQVTAASGFWE--
-FLNLEMTFD-------DLKIQT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSNLLKQQQTNLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSTG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAKLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLKA-Q-
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DLKIHT----MKDQPDE-------KSNGKKA---KGLQFLY--
---SPWWCLVAVTLAVLCLGLVVTIM--VLGMQLSQVSHLLKQQQANLTHQKNKLEGQIS
ARQQAEEAS--QESQNELKEMIETLAWKLNEKSKEQMELHHQNLNLQETLKRVANCS---
------------------------------------------------------------
--------------------------------------------APCPQDWIWHEENCYL
FSSG---SF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQEKCLSLDAQLLKINSTADL-------------------DFIQQAI
S----YSSFPFWMGLS-RRNPS--YPWLWEDG----S---PLMPHLFR---------IRG
AVSQTYPSGTCAYIQRGAVY--------------AENCILAAF---SICQKKANLRA-Q-
--------------------------------------------------------

------------------------------------------------------------
--MSEEIVYA-------NLKIQDSDKKEETQK---SDK-----CGAKV------SSAA--
---SHSQPKIVWILILLCLLLFIGMG--ILGGIFY----------TT---LAT-------
---ETIKSNQLQSVKEELQENVSLQLVHNLNNSK-------KIKTLSAMLQNIAT-----
------------------------------------------------------------
---------QLCR-ELYNKE-------------------PEHKCKPCPKGSEWYKDSCYS
QLSR---YA

PF00059 // ENSGT00700000104266_Domain_2 (370, 530)

TWQESVMVCSARNASLLKLTNKDVL-------------------EFI----
KYKK---LRYVWLALS-PRKNP--IQYP-LSE----K---IFLSEE----FERSTDDIDK
--------MYCGYIGRVNIY--------------YTYCSNQNN---IICEETASKVQ-VE
SVLSGLPEGGMYL-------------------------------------------

------------------------------------------------------------
--MSDEVTYA-------TLMLQDSAGVRGNQDGNNLRKE--------G------HPAQ--
---SS

PF08391 // ENSGT00700000104266_Domain_2 (126, 361)

LWRGAALSLMTLCLVLVTGLV--TLATMFLQVSNN----------INS-------
---DSEKLSQLQKITHPQQDNLSEPLNNSRKILTEE-SLQSQISALLEMREQMAT-----
------------------------------------------------------------
---------KLCK-EFLIHT-------------------SDHKCNPCPKTWQWYGNSCYY
FSIN--EEKSWPDSRKDCMDKNATLVKIDSTEER-------------------DLL----
QSQLSLTFSFFWLGLSWNTSG---RNWLWEDG----S---FPSPTLFSDKEL---ASF--
-----NGSRDCAYFERGNIY--------------VSRCSAEIS---WICEKRASLVK-IE
DLD-----------------------------------------------------

------------------------------------------------------------
------MTFG-------DLKKKS----MKDQPDK-------KSF----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------GKKVKGPCPQDWIWHGENCYL
FSSG---LF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEASRKNCSALGAQLLKIN------------------------DFIKQVI
S----HSNLPFWTGLS-LRKPD--NSWIWEDG----S---PLRPHLLK---------FRG
AFSHMYPSGTCAYIQWGDVF--------------ADNCILVAA---RICQKAADLLH-IQ
--------------------------------------------------------

------------------------------------------------------------
--MNLEMAVD-------DLKVKP----MKDQPDQ-------KSNGKKP---KGLRFLS--
---SPWWCPAAVALGVLCLGSLVTII--MLGMQLLQVSDLLKQQQANLTLQENILEGQVL
AQQQAEAAS--QESQRELKEMIETLAKRLDEKSKKQMELNHQYLNLQEALKRMDNFSGIP
SLNFMGEKIE-TQIQLNDKNNDKQPDLEQVS--RKNLQEAALRCLKQTNKQK--------
-TERKGALLSLCL-KIGRHSLSTHYSKMGKENAKQEVIFCTKIRSPCPEDWLWHGKNCYL
FSSG---S

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

FNWESSQEKCLSLDAQLLKINSTEDL-------------------GFIQQAT
S----HSSFPFWMGLS-RRKPD--YSWLWEDG----S---PLMPHLFR---------FQG
AVSQRYPSGTCAYIQKGNVF--------------AENCILVAY---SICQKKADLLR-SE
--------------------------------------------------------

------------------------------------------------------------
--MQAEDGYMTLNIKTQKPAVTS------------------------D------DPTA--
---SSWWRVMALTLLTLCMGMVVGLV--ALGIMSVT------------------------
------------------QQ-------------N---YLQAEKEKLSGTLQRL-AR----
------------------------------------------------------------
---------HFCQ-DLLKQA----------EKKGS----VNHKCNPCDPNWRYYGDSCYG
FFKH---N

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

LTWQEGKQYCSDVNATLLKITSRNIL-------------------EYL----
KGRT---GLIRWVGLS-RQNSS--EGWMWEDG----S---VLSKNV----FE-----L--
-SGEATENMNCAYFHNGKIY--------------PTLCKNKHY---LMCERKAGMVK-LD
QLL-----------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---SPRWRLAAVTLGIVCLGLLGAIG--ILVF---QALRPVN------------------
-----------------------------GPCSSEMSK------NHIQPSKSPPVR----
------------------------------------------------------------
---------KRDS-TKAPET---------------ITMVPEPRSRICPPNWNRNGDSCYL
FRYT---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 530)

DNWNRSKMFCESQRSHLLRINSHEEL-------------------VFIQHLT
SNN---SQMSVWIDLT-S-RSD--GSWMWGDG----S---VFSPHLFD---------IRQ
T----NSLNRCAWIHENLVF--------------DALCSSLAY---SICEEKVPH-----
--------------------------------------------------------

------------------------------------------------------------
------MTFD-------DFKTKP----MEDQADE-------KSNGQKA------------
---KPW

PF08391 // ENSGT00700000104266_Domain_2 (127, 361)

WCLAAVTFGILCLGSLVTIV--LLGIQLSQVSDLLKQQQANLTHQENILEGQSL
AQRQAEEAS--KESQRELKEMIETLARKLDEKSKEQMELRHQNLNLQEALKRAANFS---
------------------------------------------------------------
--------------------------------------------VPCPQDWIWHGENCYL
FSSG---PFDWEKSGENCLSLDAQLLKINSTGDL-------------------DFIRQAI
S----HSNFPFWIGLS-LRKPN--YTWLWEDG----S---PLVPHLFR---------LQG
AVSQRYAEGTCAYIQRGTVF--------------AENCILVAF---SICQKAANLLT-AQ
--------------------------------------------------------

---------------------------------------------------MEYHPDL--
-ENLDEDGYTQLHFDSRSNTRI-------------------AVVSEKG------SCVA--
---SPPWRLIAVILGILCLVILVIAV--VLGTM---AIWRPN----------S-------
----------------------GSNSLENGYFPSRNKE------NHSQPTQSPLEE----
------------------------------------------------------------
---------SVTP-TKAVKT---------------T-GV---LSSPCPPNWIIYEKSCYL
FSPS---L

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

NSWDGSKRQCSQLGSNLIKIDSSKEL-------------------GFIVKQV
SSQ---PDNSFWIGLS-RPQTE--VPWLWEDG----S---TFSSNLFQ---------IRT
TATQENPSPNCVWIHVSVIY--------------DQLCSVPSY---SICEKKFSM-----
--------------------------------------------------------

------------------------------------------------------------
--MNLEMTFD-------DFKSKT----MKDKPDQ-------KPNGKKA---KGLHFLS--
---SRWWCPAAVTLGILCLGLLVTLI--LLAMQLSQVSNLLKQQQANLTHQEIILEGQIL
AQQQAEKTS--QESERELKKTIETLTQKLDEKSKKQMELHHQNLNLQEALRKAAN-----
------------------------------------------------------------
------------------------------------------FSGHCPQDWLWHEENCYL
FSSG---PF

PF00059 // ENSGT00700000104266_Domain_2 (370, 531)

NWEKSQENCLSLDAQMLIINSTEDL-------------------EFIQQAS
A----HSNFPFWMGLS-LRKPS--SSWLWEDG----S---PLMPHLFR---------LQG
PVSHVYPSGSCAYLQRGAVF--------------ADNCILSAF---TICQKKANLLR-AP
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------DLKFQDSSKTENIQE---LDK-----FGNKG------KILM--
---SD-------------------IG--IIRFEFL----------IDLS---I-------
---F----------N-----------------------------------QRYPNK----
------------------------------------------------------------
---------MIIK-GFVKTL-------------------FKHKCKPCPKRWMWHEDSCYL
LCND---T

PF00059 // ENSGT00700000104266_Domain_2 (369, 531)

QPWQESKMACAAQNASLLKINNKSTL-------------------DFI----
KSQ---RLYDYWLGLS-PRKDYVYSY-YELDK----I---FNSSDW----EIRNTTDL-N
E-------RYCGYLRGIYVD--------------YDDCVKGKK---MICEKMANPVK---
--------------------------------------------------------

---------------------------------------------------MEYHSDL--
-ENVDEDGYTQLNFHSQGITRR-------------------PVISEKG------TPAA--
---

PF08391 // ENSGT00700000104266_Domain_0 (124, 152)

SPPWRLIVLTLGILCLIMLVIAV--VLG

ENSGT00700000104266_Linker_0_2 (152, 367)

TTX----XLRS----------S-------
----------------------GSNSLKNDNFPSRNKK------NLSQPTRSPLEE----
------------------------------------------------------------
---------SVAS-KALKTT---------------G------RADPCPPDWIFHEKSCYL
LSMS--

PF00059 // ENSGT00700000104266_Domain_2 (367, 486)

-LDSWTGSKSRCSQLGSNLLKIDSAEEL-------------------TFIGRQV
SSH---PDNSFWIGLS-RTQTE--QPWLWEDG----S---TFSSNLFE---------IRS
TAIQEN------------------------------------------------------
--------------------------------------------------------

------------------------------------------------------------
--MSEEVTYA-------TLTFQDSAGARNNRDGNNLRKR--------G------HPAP--
---SPIWRHAALGLVTLCLMLLIGLV--TLGMMFLQISND----------INS-------
---DSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAI-----
------------------------------------------------------------
---------KLCQ-ELIIHT-------------------SDHRCNPCPKMWQWYQNSCYY
FTTN--E

PF00059 // ENSGT00700000104266_Domain_2 (368, 531)

EKTWANSRKDCIDKNSTLVKIDSLEEK-------------------DFL----
MSQPLLMFSFFWLGLSWDSSG---RSWFWEDG----S---VPSPSLFSTKEL---DQI--
-----NGSKGCAYFQKGNIY--------------ISRCSAEIF---WICEKTAAPVK-TE
DLD-----------------------------------------------------

------------------------------------------------------------
--MHEDEVYTSLQWNDPPSN-----------SSQ------------KC-------GC--F
RTC

PF08391 // ENSGT00700000104266_Domain_0 (124, 173)

SGAWHVVMVILCISCMGLLATSI--FLGVKLFQVSSMAMKQQEKLNQQD

ENSGT00700000104266_Linker_0_2 (173, 367)

KALLNF--
--------T-------RWQRNYVL-----------------QTRHCQPSMATFSSP-D--
------------------------------------------------------------
-----------------------------------------HYCRPCPDNWIQNGESCYY
VSDK--

PF00059 // ENSGT00700000104266_Domain_2 (367, 531)

-WQTWDAGKEACLKECSRLLQIDSQEER-------------------DFIISSL
RKI--KKDYDYWVGLS-RDALN--RTWLWQDG----S---SPFPDLLPG-----------
-ETSQSTSQVCGYLRNKSLF--------------SANCSNWKF---FICEKYALRSS-I-
--------------------------------------------------------