Query Results 

---MA---EEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-IYANHVLLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNE
KTQAVVNEKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSGL
LQ-LQGTTSAAAPCSLKMEASCCVLRLLCCAEDVATGL----LPGTVTMETPTKVARPTQ
TSS----QRVPLWPIS-----HFPTSPRSSHGLP--PGIPHTPSFTASQSGSEILYPPTQ
HPPVAILARNSDNSMNPVLNCSLEMEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVYFFFHLLHFQLDMSTYKEAETQ-----NTTLNVYLCQSE
DS---CLE---DSDPSNLGYELISAFVTKGVYMLKAVIYNGFHGTEVELGPYYVEIGHEA
VSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDVIFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRISSVVSEPHVIRVQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECWINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNDVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 751)

TLRKQLFIVCEPCQPPL
VKNMGPGKVQIWRSQPVRLGVTFEAAVFCD

PF02010 // ENSGT00700000104221_7_Domain_2 (751, 1407)

ISQGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTQSFDPD-----NPGATLRYHWECATAGSPAHPCFDSSTAHQLDAMAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYADSAFRFV--HISWVSFKDTFVNW
NDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISESS
QLNLLPTEP----------GTADPD-ATTTPFSREPSPVTLGQPAPSAPR-----GIPTE
PMTGVYWIPPAGDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPDPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPGSGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAEPVLMIDWPKALLGQAVFQGYSSS-GITEQTVTIKPYSLSSGETYVL
QVSVASK--HGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLGFMSAVLILKYTR
ALLAQG---QFSGPFVVDKGVRLELIGLI-SRVWEVSEQENSKE-EVYLHEEGITVISDL
LLGCLSLN-----HVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SLCYISQLILFKKNPYPGSQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGLDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPN
RYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYHRLA-AFALLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG--QGWFFPAQCW
LSASRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGRQEQHQLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGS-ARVEPHS-PLRG--GAQTEAPHDPNS---------WRR-VPDAQEP---C
KQPASAILSGSGRAQRKAAS--------------DNG---TACPA-PK-LQVHGADHSRT
SLMGKS---HCCPPHNQAP--SSGLEGL-MPQWSRALQPWWSSAVWAICGTASLACSLGT
GFLAYRFGQEQCVQWLHLMSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLCEATRDL-DSELAERSWTRL----PFSSSCSIPDCAGEVEKVLAARQQARH
LRW--ANPPSKAQLRGTRQRMRRESRTRAALR--WVAKQLFIFVL---------------
---------ALRNARNSLGGLRNITDWWDWSLTTLLDGLYLGGTPSARVPGAQPGALGGK
CYLIGSSIIRQLKVFPSHLCKPPRPFSALIEDSIPTCSPEV-GGPENPYLIDPENQNVTL
-NGP------GGCG----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2902)

VLSLGRTRT--EAHTALSRLRASMWIDRSTRAVSV
HFTLYNPPTQLFTSVSLRVEILPTGSLIPSSLVESFSIFRSDSALQYHL--------MLP
Q-LVFLALSLIHLCVQLYRVMDKGVLSYWRKPRNWLEFSVVGVSLTYYAVSGHLVTLAGD
VTDQFHRGLCQAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS---M
TRHSLP--SIFVAGLVGALMLAALSHL-HRFLL-SVWVLPP-GTFTDAFPR--LLFHFPR
RSQKDCLLGL---SKSDQRAMACYF--GILLIVSATLCFGMLRGFLMTLPQKR-KSFQSK
SFVRLKDVTAYMWEKVLTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKTSN-----NTGEARTEESPLVDIS-SYQAAEVRPCKIIYVNFLHSNLSSK
GVLE---------------

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PLKSQCTRPVVGSCSVTVGTPSCTMGRQRSAEDVAPDL----LPGTDVTSATVVMGEPVK
VSPDLGSRSACFWAGCSPPVSV----------PPGRPSCSL-KPSFLSLSHDGSLCPLAQ
CLPGAISVQGPADAVDPAVRCFPEADTRAPPSLGFRVQVASEASLCLLLDFGDGCGVQVR
IRNVSEGTAVTAFHQFGKGGWSGVHLEH----GQ--------------------------
----------------RWSFFL---PFPEGVYTLKAVIHSEFRGTEKELGPYYVDIGPAT
VSVSMNSSSIHKDGLLVLTDSHTDQKGTVVTHRFPTGPSWNVSFTSRTRAGGGRAWKPVT
VRFQMQPVSV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 621)

YTNGTVFATDTDITFLAVTKETVPLEFLWYFGEGPPVRTTSRS--VR-KR
LRIPQWYSVTVQASSRLGRV

ENSGT00700000104221_7_Linker_0_1 (621, 639)

ASEPHRIRAQRRIIANRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 704)

ASPSSALLNTSVTFECRLNFGS
DVAFLWDFGDGAVGPGGSSASHSYSREGEFTVQVLAFNDVSTA

ENSGT00700000104221_7_Linker_1_2 (704, 752)

SLRKQLFVVREPCQPPP
VKNMGLGKVQVWRSQPVNLGVTFESAILCDI

PF02010 // ENSGT00700000104221_7_Domain_2 (752, 1383)

SQGLSYTWTFWNSEGARVPLPPAISTHRQ
TLTIPGYFLQPGNYTALAKVQVEGSVVHSSYRVGVEVRARAPVSVISEGTHLFISRA---
PSFIIVLRGSQSYDP-----DSPGAVLRYHWKCTAASAPGHPCFSASSPHSLDAGAPTLS
FPADSLSDTYDQFLVTLTVSSSGRNSSEAQVFLSPRPNSALRFV--HISWVNFRDIFVNW
NEELCLQAECEVCGQVSGLSYSWDLFLVNATEGTSVEVPFCRTVGLLGSAGL-GAISRPP
ESSPPSTEP----------SWPECH-TTGAPFSQEP-PQTRGQPGLSAAG-----KPSSG
PTVSRHWVPATGDAAAPG------VTPQDQ-GS--PGPSSPGGSSPS-------------
-QGLSPSPSDFEVYYGNIQEAE-LSRGRQPADCDL----PGSDPSSS---ADRAR--GDG
DNLLGPLPPTAAAGPPLMVDWPKSPVGRTLFHSYTAS-GITGQTVTIKPFALSPGKTYVL
QASVASK--HNFLGRAQLYVTLRPAPWAMTCQVQPHRGL--EAHTIFSIFCMSGRPDFHY
KFSYRIGNGS-RHTLYRGTDTQYYFALPAGEPLDDYKVMLSTEITDGSGSRAQPCAVAVT
VLPRLHG-----GLCLDEDIYNSSLKHLSTLQLMGSYAEIRNYITMIAR-ILSRWAAEDR
SP-PCGQWSRIQDALISSACRLPSADQEEMLDSVLLFRDLLRFPHKVSFTSAALVLKSTQ
ALLAQS---LLSGRPAVAEGTMLELILLV-SAIWEVSDQETPRN-VGFLQEEGIKVISAL
LL----------LCISAGQMEFCTLLHHDRQGTMQSLGPVRVHLPGGLA-GQRPAAAGMQ
SPCYISQLMLFKKNPYPGRRAPG-QIGPL-VALSLFTCSGRRPISRQRLREPVVVEFGE-
-EDGLGERRNRMTFALLREAVNFHRFT-GRSESPQESLQIRIEFSRPVSRAFPVMVLVR-
FSEKPTPSDFLVKKVYVWDEPMVHVYVPAASLRD-------TSLGYLSLLDADYDRMPRN
KYFAKAVNYTVRFQWLRCVFWE-TREWRSANSSPQPGASPGKVSCSYDRLA-PVSVARRN
LSASFSVEGVSKLQRHPGNLLPSILIAVSVVLYALLVTNTRRVDRHEREKAGYISLQEDT
P-ADHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2043)

YAVVVDTGFRAPAHCSAKVYI---VLCGENGVSEPRELYCSEK-PLFE-----
-RNSRHTFVLSTPALLGPLRRIRLWHDSRGPCPAWYVSHLMVQELGTGPAQHWLFPAECW
LA

ENSGT00700000104221_7_Linker_6_7 (2043, 2665)

AGRGDGHVQRELGCLRRGPGFWKLLYSKFTEYLEDFHVWTSVYSRPSPSGFLRTPRLT
VAFTLLCAYACLA----------LLWALGAPDTA-AGSFQTGLLCTLLASPAAQLLSLLL
RLSQVPTAR-LPG--------PAVQ---GP-P--SPR--------DPCL-----------
---NSHLLPQEPSGPRRV------K-------P---------RLP-PR-RAPMG-AAQGR
C-------------------------------------------AF------KKAGTDGY
SLPGDRFNPTQCAQWLHLLTLSVLCCVFVTQPLLVGL-VALGFAWRKRDDPH--------
---FFTESLREATKDL-GSELEGRVRSPM------------AHRASQMEEMVAARQRARR
LRW--ARPPSAAQLSVTRERMRRETRTRVALR--DVCMHTLMLLLHWFVLCGKVSQD-EY
SLHQAIRNEFTRNARSSSGGLTSVGAWWDWSLTTLLDGLHGQGAHTAGVPHAQPGALGGK
CYLMGALVIKQLRLPSPPSVLTE----DSPPTR----SPQV-GATDTSSVTDPAIQGVAA
-SGP------GDYG----AR--EH

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2903)

WVLSLGSTRA--AAHAALSGLRASRWIDRSTRAVSV
HFTLYNPPTRLLSSVSLRAELLPAGGLALSPLVESVAIFHSNSSQWYRL--------TLP
E-LVFLALNLIGLCLHLSGMAETGVRSYWHSPGLWLELTVVGAGLAYHAASSHLVTLTGE
VADHFQKGLFHEFLDLSLVTSWNQRVSWLQGTLSFVLTLKCICLVGVQTPVASCSF---L
TRRSFA--GVFAAGLAGVLMLAAHSHL-ST--------APP-GTFTDVSRG--LLFRFPG
RRQRDTFPGL---SKSDPRAPAWCC--GAFFIVTSTVWLGTLRGSLMTLVRK-RKSFQSK
SLVSLEDVTACVWGQCLALLGLERPQGEEAETVESQHY-YLD-EVSDLLEELLLKINGLS
DSLRLPRPEQQSC-----DETEARAEGGPLGSIS-A------------------------
-------------------

-----------PAEEAGRVTRCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCDCPRCALKRQAEDRESQSPSSLPSGQKNIWKTTSKVALSVVN-
-------EKTQAPLDCDNSADRIPHKPSIIIVRAWSSGGPRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAASCSLKMEASCCVLRLLCCAEDTAMGL----LPGTVTMETPTKVARPTQ
T--------IPLWPIS-----HFPTSTRSSHSLP--PGTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQNSDNSMNPVLDCSLEMEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVIF-FLLLHFQLDISTYKEAETK-----NMTLKVYLCQSE
NS---CQE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTKVELGPYYVEIGREA
VSAFMNSSSVHEDEVLVFTDSQVNQKSTVVVHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYRMQSVSVYTNGTVFATDTDITFTAITKETIPLEFEWYFGEDPPVRTTLRSIK---KR
LSIPQWYRVMVKASNRISSVVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTIRLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCKPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYTWNLMDSEGLPVSLPAAVDTLRQ
TLILPSHALEYGNYTVLAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDPD-----NPGATLRYHWECTTASSPAHPCFDSSTAYQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLYLVNATEKNKIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTVDPD-ATTTPFSREPSLVTLGQPAPSAPR-----ETPTE
PVTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DAS-FPESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPVLMIDWHKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAYTIFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSMEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIDSVLMLRDLVSFSNKLSLMSAVLIFKYTR
ALLAQG---QSSGPFVVDKGVRLELIGLI-SRIWEVSEQGNSKE-EGYLHEEGITVISDL
LLGCLPLN-----HISTGQMEFRTLFHYNLQSSVQSLGSLQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGPDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ANVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKAERFSPQPGTSPEKVNCSYNRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGFLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYV---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTRLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAQSHC-LPRG--EAQAEAPQGPNS---------YQR-VSDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSRT
TLMGKS---HCCPPCTQAP--SSGLEGL-MPRWSRAPQPWWSSAVWAICGTASLACGLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----PFSSSCSIPDSAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISVDILMLLLLLGIMYGRFSQD-EY
SLNQAIRKEFARNGRNSFGGLRNITDWWDWSLTTFLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPWPFSAPTEDSIPTCSPEG-GGPENPYLIDPENQNVTL
-NGA------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2901)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLVPSCLVESFSIFRSDSALQYHL--------VLL
Q-LVFLALSLIHLCVQLYHMMDKGVFSYWQKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCVYLPGIQNTMASCSS---M
TRHSLP--TIFVAVLAGALVLAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYF--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKALTFLRLETPKREEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENTSN-----STGESRAEESPLVDIS-SKQATEVRPCKIIYVNFLYRNLSSK
GVLE---------------

---MPDPHSLEEHALRAASEQCIRAVCCLSFCGEMPVSTDKSWGLHLCSCS--PPEGGVW
V-EVCANHVLLTTDEQCGCPQHALNGKAEDCDSQSPSALASGEKNTWKTTSQAVSSAVN-
-------EKTRAPLDGDNRADSIPHKPFVILASAWNSSGPRFHRRRLCAAGTTGSTSSGL
LQ-VQGTSSAAAPCSLKMEASRCVLRLLCCVEDAASGL----LPRTVTMETPTKAARPIQ
TST----QGVPLWPVS-----HFPTSPRSSCDLP--PGTSHTPSLTASQPGPESFYPPTQ
HPPVAILAQNPDDSMNPVVDCFLEMETWAPPNLGFRVHMTSGKAVCLMIDFGDSSGVEMR
LHNTSEAMVVTAYHQYAKGKVHSQR----------------HK-----IEFLKVYLYQNE
NS---CQE---NSDP-----KLLYAFVTR--MFLKTVIYNEFHGNEVELGPYYVEISHEA
MSVFLNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISPSQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDITFAAITKETIPLEFEWYFGEDPTVRTTSRSIK---KR
LSIPQWYRVMVKASNGISSVVSEPHVIRMQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 703)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSA

ENSGT00700000104221_7_Linker_1_2 (703, 749)

SILRKQLFIVCKPCQPPL
VKNMGPGKIQIRRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDLSQGLSYTWKLMDSDGLPVSLPAAVDTHRR
TLLLPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVQAQAPVSVISEGTHLFFSRT---
ASSPIVLRGTQSFDPD-----NPGASLRYHWECTAASSPGHPCFSPSTAHQLDAGAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPHPDSAFRFL--HISWVSFKDTVVNW
NDELSLQAICEDCGEMPDLSYSWDLFLVNATDKNRIEVPFCRVVGLLGSLGL-GAVSTSS
QSNLLSTEP----------GTADPD-ATTTPFSWELSPTTLGQPAPSAPR-----GTPTE
PVTGVYWIPAVGDSAVPG-----EAPEE-GLLDLEPEPQSKGSLMTDPL------ERSQP
THNPDPHPSDFEAYYSDIQEAI-PSEGRQPAN--DTS-FPGSGPSLSA--K-ESP--GDG
DNLVDPSLSAGRAKPVLMIDWPKALLGRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--LGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTVFSVFCMSGKPDFQY
EFSYHIGNTS-KHTLYHGRDAQYYFVLPAGEHLDNYKVTVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGIYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSQTQDALISSVCKLAFADQEEMAGSVLMLRDLVSLSSKLSFMSAVLILKYTW
ALLAQG---RFSGPSVVDKGVRLELIGLI-SRVLEVSEQENSKD-EGYLREEGITVITHL
LLGCLSLN-----HVSTGQMEFRTLLHRNLQSSVQSLGSVQVHLPGDLA-GHSPAGAETQ
SPCYISQLILFKKSPYPGGQVPG-QIGGV-VGLSLYNCSSRRPINRQWLRKPVMVEFGE-
-EDGLDNRRNKTTFVLLQDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESVVQIYIPAASQKD-------ANVSYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYNRVA-AFALLRRK
LKASFEVSGISKFQSHPENLLPSIFIMGSMILYGFLVAKSRQVDHHEKKKAGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGRSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKICLWHDSCGPSPSWFISHVMVKELHTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLRGGLGFWKLFHCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVTAGGQEQPQLDVSP----SLESFKVGLLCTLLASPGAQLLSLPF
RLSKEALGP-VQAEPHS-PLRG--GARTEAPQGSNS---------CRR-ISDAQEP---C
KHPASAILSGSGRAQRKAAS--------------DSG---TSCPA-PE-LEAHGADHSGT
ALTGKS---HCCPPQAQAP--SSGLARL-MPQWSRAPLPWWSSAVWAICGTTSLACGLGT
GFLGYRFGQEQCVQWLQLLALSVVCCVFITQPLMVCL-VALGFAWKRRADNH--------
---FFTESLFEATRNL-DSELAERSWTCL----PLSSSYSIPDCAGEVEKVLAARQRARH
LRW--AHPPSKAQLRVTREGMRRQSRTRATLR--NISMDILMLLLLLCMIYARFSKD-EY
SLNQAIRKEFTRNARNSLGGLRNISDWWDWSLTTLLDGLYPRGSPSPRVPGAQPGALGGK
CYLIGGSVIKQLKGFPSHLCKAPRPFSALIEDSLPMCSPEV-GSLEKPCLIDPENQNVTL
-NGP------GGCG----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2895)

VLSLGRTRP--EAHAALSRLRASTWIDCSTRAVSV
HFTLYNPPTRLFTSVSLSVEILPTGSLVPSSRVESFSIFRSDSALQCYL--------VLP
Q-LVFLVLSLIHLYVQLHRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCHAFMDLTLMASWNQRARWLQGILLFLLTLKCAYLPGIQNTVPSCSS---V
MRHSLP--SVFVAGLAGAPMLAAVSHL-CRFLP-STWALPP-GTFTDAFAM--LLFRFPG
RSQKDSFLGL---SKSEQRAMACYF--GALLIVSATFCFGMLRGFLMTLPRKR-QSFPSK
SLVRLKDVTAYMWEKVLTVLRLEAPKLEEAEMVENHNY-YLD-EFANLLDELLMKINDLS
DSLQLPLLEKTSN-----STGEARAEESPLVDIS-SYQATGVRPCKIIYVNFLHSNFSSK
GVFEYLLFQNIRSICINIL

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----------------V

PF02010 // ENSGT00700000104221_7_Domain_2 (798, 1387)

FQVQIKGSMVYSNYCVGVEVRPRAPVSVISEGTHIFIPRA---
TTTPIILRGFQSYDP-----DNPGAALSYHWTCTAASSPRWPCFEDSTLYQMDTHAPSVS
FQARWLSECCDQFLLTLTVSSNGQNSSQALIFLSTHPDPAFRFV--HISWANFRDIHVNW
NEELSLRAVCEDCDNVPDLTYSWDLFLVNATEKNMVEVPFCSTVGLLGSSAF-GALLKLS
QSGLQSN----------------PR-GPLTLHSPQRSPMPLSWTTLPNLG-----STSTE
STAGGHHIPVVGPLAGSG-----EPMEDYGSLSPAPGSSDEQALMMSTP------EGSWP
PSSSSPAFDDFEAYYSDIQEDV-PSLGRQPGS--GTN-FQESGPSMDA--E-ESA--SDG
DNLLGPFLHTGREKPAFMIDWPKTLVSRAVFHGYTSS-GIVGPAVTIKPFSLSSGEMYVL
QASAASK--HALLGKAQLYITINQVPRDMSCQVRPHSGL--EAHTIFSVFCMSGKPDFHY
EFRYQIGNTS-PHTLYRGRDTQYYFLLPAGETLDNYKVIVSTEITDGQGSKVQPCTVEVT
VLPRYHG-----NDCPDKDLYSSTLETLSSLQLVGSYTEIRNYIAMTTA-ILSRLYVESK
NTSMCGLWSQIQDVLISSACKLPSTDQEAMMDSIHILRDLINFPNKLSWLSAMHILKYAQ
MFLRQG---QFSRKLLVNKKLGIELILLI-SGVWEAARED-KRN-GDYLQEEGLKIISDT
LL----------LHISTGQMEFWTVLHHSFQSSVQNLGFIWVHFPGDLA-LHSSALEESH
SPCYISQLMVFMSSPYPAGQAPG-QVGGV-VSPRLYSCKSRRPILRGRLKTPVTVEFGE-
-EDHR-HKRNPTMYTLIRDEINLHQFI-GLSEKPQETLQIQIEFSKPVTRAFPIMLLVR-
FSKKATPADFLVKQVYFWDEQTVQIYVPAVPVKG-------TNVGYLSLLDADYDRRPPN
KYLAGAVNYTVNFQWIQCVFWDK-TGWRSEGPCPHPGSSPEKVNCSYHRLA-PFSILRRK
LNATLEMSSISGFRSHPHNLIPGIFSVFLLVLYGLLMTKSRCVDCHKKKKPGCIFLEEGI
P-PGHQLYA

PF01477 // ENSGT00700000104221_7_Domain_6 (1930, 2045)

VIIDTGFRSPAQFTSKVFI---VLYGENGFSGTKELCCPEM-SLFG-----
-RNSRHTFILSTPNQLGPLQKIRLWHDSSGPSPNWFISHVMVKELHSG--QGWFFLAQCW
LAVS

ENSGT00700000104221_7_Linker_6_7 (2045, 2668)

LCDGRVQRELFCLRRGLGFWKLFYSKFTEYLEDFHIWLSLYSQPTSSSYLHAQRLA
VSFCLLCVYSCLTALVTVGVHEQRSLDVGPT----LESFSLGLLCTILACPATQLLSLLF
RFSKETAGH-LRDAPQ--WPLG--GVKTEAPQGSDHS--------GR---PSLRQP---F
QHPASDILPMTDGDWRMAAS--------------SSG---MVCPS-FL------------
SVSEKS---QHLPPRSQAP--SSGFKGL-VPQRSRVCLLLSRSVAWAICGSASLACSLGT
GFLGYRFVPEQCTWWLHLLLLSVVCCTFVTQPLMICL-AALVFAWKRKHDSQ--------
---FFVESLHDATKDL-DLELEEYSRAHI----LHFRSSCSPDSAEEAERVLAARQRERH
LRW--AQLASRAKFRVTKERLKKESQLQAALR--DISMHSLMLLLLLFITYGRLCPG-EY
SLNQAVRKEFTRNARYSFGKPSSTDDWWDWTVSTLLNGLYPEGPAA-GAWGAQPGALGGQ
CHLIGPSVIKQLKVSSGTACTPPRPVSELMEDALSTSTRDL--D--------LENPNVTH
-GGP------EACG----VKK-ENSMH

PF08016 // ENSGT00700000104221_7_Domain_7 (2668, 2903)

SLGRTRH--EVHSALTALRANRWIDHSTRAMSV
HFTLYNPPMRLFTSVTLGAEFLPMGGLVPSSLVESFSIFYSDSVPQYLL--------MLS
E-LVFLVLNMTHLCFQLWGMATNGVLSYWKKPRHWLELSMIGVALAYYAASGHLTTLAKN
VNDQVHKGLHQMSVDLSLMVSWNQRARWLHGSLLFLWILKCAHLLGFLNTMTSFSE---V
TCSSLS--RAFAPALLGALLLAAHSHL-YRFLL-VTWTPSS-STSTDAFPR--LLLQFLG
RSQRDSLNNH---VEPDHQAMACYR--GALFLLVATLCFRMMRASLLTFFRKG-KSFHRK
SLVILKNVAVYAWRKFLTLLGLETTTLEETGLATDHSY-YLD-EFSSLLDELLVKIDGLS
DNLELSILEEQWR-----RTVEARAVDSPLVCLS-GCQATGVAGSLDAE---------SS
-------------------

---MA---EEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVN-
-------EKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFYHRQLCATGTADSIFSGL
LQ-LQGTTSAAAPCSLKMEASCYVLRLLCCAEDVATGL----LPGTVTMETPTKVARPTQ
TSS----QRVPLWPIS-----HFPTSPKSSHGLP--PGIPRTPSFTASQSGSEILYPPTQ
HPPVAILARNSDNSMNPVLDCSLEMEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMVVTAYHQYSKGN---FFHLLHFQLDMSTYKEAETQ-----NTTLNVYLCQSE
NS---CLE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEVELGPYYVEIGHEA
VSAFMNSSSVHEDEVLVFADSQVHQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYKMQSVSV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDIIFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVTVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHIIRVQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECWINFGT
DVAYLWDFGDGTISLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRQQLFIVCKPCQPPL
VKNMGPGKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISQGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSRIVLRGTQSFDPD-----NPGATLRYHWECATAGSPAHPCFDSSTGHQVDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSAFRFV--HISWVSFKDTFVNW
NDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISESS
QLNLLPTEP----------GTADPD-ATTTPFSQEPSPVTLGQPAPSAPR-----GTPTE
PMTGVYWIPPAGDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPDPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPGSGPSLSA--E-ESP--GDG
DNLLDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSS-GITEQTVTIKPYSLSSGETYVL
QVSVASK--HGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLGFMSAVLILKYTR
ALLAQG---QFSGPFVVDKGVRLELIGLI-SRVWEVSEQENSKE-EVYLHEEGITVISDL
LLGCLSLN-----HVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGSQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGLDNRRNKTTFVLLRDEVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPK
RYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYHRLA-AFALLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKASYIFLQEAS
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG--QAWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQPQLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGS-ARVEPHS-PLRG--GAQTEAPHGPNS---------WGR-IPDTQEP---C
KQPASAILSGSGRAQRKAAS--------------DSG---TACPA-PK-LQVHGADHSRT
SLMGKS---HCCPPHTQAP--SSGLEGL-MSQWSRALQPWWSSAVWAICGTASLACSLGT
GFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCL-MALGFAWKRRADNQ--------
---FFTESLCEATRDL-DSELAERSWTRL----PFSSSCSTPDCAGEVEKVLAARQQARH
LRW--AHPPSKAQLRGTRQRMRRESRTRAALR--DISMDILMLLLLLCVIYGRFSQD-EY
SLNQAIQKEFTRNARNSLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGK
CYLIGSSVIRQLKVFPRHLCKPPRPFAALIEDSIPTCSPEV-GGPEDPYLIDPENQNMTL
-NGP------GGCG----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2903)

VLSLGRTRT--EAHTALSRLRASMWIDRSTRAVSV
HFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------MLP
Q-LVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGD
VTDQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS---M
MRHSLP--SIFVAGLVGALMLAALSHL-YRFLL-SMWVLPP-GTFTDAFPG--LLFHFPR
RSQKDCLLGF---SKSDQRDMACYF--GILLIVSATLCFGMLRGFLMTLPQKR-KSFQSK
SFVRLKDITAYMWENILTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKTSN-----NTGEARTEESPLVDIS-SYQAAEVRPCKIIYVNFLHSNLSSK
GVLE---------------

----P---AENLAQSFKDVTVCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMRDGKCDCPRCALKTKAEDRESQSPSSLPSGQKNIWKTTSKAALSVVNE
KTQAVVNEKTQAPLDCDHSVDRIPHKPSIIIARAWSSGGPRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAAPCSLKMEASCCVLRLLCCAEDTAMGL----LPGTVMMETPTKVARPTT
T--------ITLWSIS-----HFPTSPRSSHSLP--PSTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQNSDNSMNSVLDCSLETEARAPPNLGFRVHMASGAAVCLMTDLGDSSGVEMR
LHNMSEAVAVTAYHQYSKGKVIF-FLLLHFQLDISTYKEAETK-----NMTLKVYLCQSE
NS---CQE---DSDPSNLGYELISAFVIKGVYMLKTVIYNEFHGTKVELGPYYVEIGREA
VSVFMNSSSVHEDEVLVFTDSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSVT
VWYRMQSISV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---QR
LSIPQWYRVMVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCEPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTVLAKVQIEGSVVYSNYCVDLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDP-----DNPGATLRYHWECATASSPARPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTADPD-ATTTPFSWEPSLVTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAEDSVVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPVK--DTS-FPESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPVLMIDWHKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDSQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLAEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCHQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLSFMSAVLIFKYTR
ALLAQG---QSSGSFVVDKGVRLELISLI-CRIWEVSEQGNSKE-EGYLHEEGIMVISDL
LLGCLPLN-----HVSTGQMEFRTLFHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGRQAPG-QIGGV-VGLNLYTCSSRRPVNWQWLRKPVMVEFGE-
-EDGLDNRRNKTAFVLLRDKVNLHQFT-ELSENPRESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------VNVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSELFSPQPGTSPEKVTCSYDRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGFLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQLYA

PF01477 // ENSGT00700000104221_7_Domain_6 (1930, 2047)

VIIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSTPAQLGLLRKICLWHDSRGPSPGWFISHVIVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFTLLCVYACLTALVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAEPHC-PPRG--EAQAEAPQGPNS---------CRR-IPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSGT
ALMGKS---HCCPPCTQAP--NSGLEGL-MPWWSRAPQPWWSSAVWAICGTTSLACSLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----RFSSSCSIPDCAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--WIPWTSYAALL--LVNYGRFSQV-NT
PQS---SYPKFRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPRPFSAPTEDSIPTCSPKG-GGPENPYLIDPENQNKTL
-NGP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2897)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------VLP
Q-LVFLALSLVHLCVQLYHMMDKGFLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCIYLPGIRNTMASCSS---M
TRHSLP--SIFVAVLAGALMLAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYL--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKTLTFLRLETPKLEEAEMVEYHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENISN-----STGEARAEESPLVDIS-SKQATESPPSDLK------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------Q

PF02010 // ENSGT00700000104221_7_Domain_2 (800, 1421)

VQIKGSVVHSNYCVAVEVRSRVPVSVISAGTHLFVPRV---
ALVPIVLSGSQSYDP-----DNRGAVLRYLWACTVASSPGRPCFDNAPPHQLDARAPTVS
FLAGWLSGCCDQFLVTLTVSSGGRNSSEAQVFLSTRDDPAFRFI--HLFWVNFKDIHVNW
NEELSLQAVCELCEDIHDLSYSWDLFLVNATEKNRMEVPFCSTVGLLGASAL-EAVLKSS
ESNLLAAEP----------SMADGN-GRPTLSWLGPS--------LSTLA-----PPIIS
VTENGYYLPAGGDTMAPA-----E-SPEDELQSPETGSLAEG---------------SWP
QPSISPALDDFEAYYSDIQEAV-PSRGRQPGDSSNGQEAEDRRPSSQ---AEGNP--YDG
DNLLGPFLSPSRAGPVLMTDWLKTQVRPAVFQGYTAS-GITGSSVTIKPYSLSSGETYVL
QASVASK--HGLRGRAQLYFTVNPTPQDMACQIWPHHGL--EAQTIFSVFCLSVNPDFHY
EFSYQLGNAS-KHTLYRGRDTHYYFALPAGEPLDSYKVMVSTEITDGKGSRVQPCTATVT
VIPRFHG-----NSCLSQDLYNSSLNSLSTLQLMGSHREARNFITMITG-ILRRLSKENR
ST-SCGQWLQTQDVLISSLCKLVFTDQEEIIDSILLLRDLVSLPHKLSFVSAVHILRYSQ
ILLAHG---QFLERFVVDKGLGLELILLI-AGVWEASTQENLTS-ENYLQEEGMKIISDV
LL--------HQFHMSTGQMEFWILLHHNLQSSVQSLGSVQVHLPGDLA-WHTLAQEEMQ
SPCYISQLLFFKKSPYPRVPDPG-QVGVV-VGITLYSCSSRRPIPRGRLQTPMTVEYGE-
-EDSPDNNRNTTTFVLLRNQVNFHQFT-GLSGNSQGSLQIHIEFSNVKTRAFPVMLLVR-
FFEKPTPSDFLVKQIHLWGEQTVDIYIPKGQWAGRNLFVFRANMGYLSLLDADYDRRPPN
KNFTKAVKYTVCFQWLQCMFWD-KREWKSESFSPQQGASPGNVNCSYHRLA-SFSLLRKK
LNASLEVSDISELQKHPQNLFPSILIVVFVILYGVLITKTRHVDCHNKKKTEYIFLQEDM
P-PGHHL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2045)

YALVLATGFRSPARFTSKVFV---VFCGENGLSETRELYSPEK-PLFQ-----
-RNSKHTFILSVSAQLGPLQKICLWHDCRGHSPSLFISHMMVKNLCSG--QGWFFHAQCW
LAAS

ENSGT00700000104221_7_Linker_6_7 (2045, 2667)

RGDGRVEREFTCLHHGLGFQKLFYSKFTEYLQESHIWLSVYSWLSSSGYLHVPRLA
VSFCLLCVYAYLAALVTSGGHEQPLLVVGPADI-TLRSLGLSLLCTFLAAPAAHLVSLLF
GLKKPARVG-AHQSDCM-QLPI-----------------------GCQ------------
------------------NWL----------------------------YFL--------
---LHN---HVVPELDQVH---------TGSFMSRAYPPWLSSAGWIMCVLVSLACGVGT
GFLGYRFVPAQCVQWLYLLSLSVVCCACVTQPLMICC-MTLAFAWKRKDDKD--------
---FFTGSLCEATRSL-ALGLSLGSGAHL----ALSPG-GAPVCAGEAEKVLAARRRERH
LRW--ARPPSMAKLRSIRERLRRQGQTQAALR--DICMSILTLLLLLLIIYGKVSPA-ER
SLSQAFRKKFMREARNYLGDLRGPDGWWDWCVTALLDGLYPEG----LSAAGQPGALGGK
CYLLGTPVIKQLKVFPCGPCKSPRPFWMFIGGSDPMCRPET-QGLA--------NQSVVS
-CSP------EACG----ARK-EACV

PF08016 // ENSGT00700000104221_7_Domain_7 (2667, 2784)

HSLGRTRP--KAHAALAALRASRWIDQSTRAVSV
HFTLYNPAARLFSSVTLSVEILPTGGLTPSFLVQSFSIFHSDSAPQYYL--------MLL
K-LIFLVLHLAHLCLQLCGTAEEGLLSCWRKPRTWLEVGFHGSSAQ----GEHSTTCATA
PLPVFSSGLLE-----------IGRVQWLQGLLSFFWMWKCIHALGFLNKMVSCSS---R
MCL-----FVIRVFLAGVLLLAAHFHL-LSFLL-FTWVLPS-NPSADPIRR--LPFHFLG
RNQKDFFHSL---PEAGRRSTACFC--VAFFLLMATMSFRMLSSCFQIFFRK-RKSPHRQ
SLVTLKDVAAHVWKEVQTLLGLEKPKVEETEETGEHNY-YLD-ECSLLIDELLRKINGLS
DSLELPGLENQPG-----RTVERRADDSPLAGIS-QY-----------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------VQVEGSVVYSNYCVQVEVRARAPVSVISEGTHLFISRT---
LVSTITLRGSQSHDP-----DYPGAILXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXX-X----------XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX
XXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXX
XXXXXXXXCDFEAYYSDIQEAE-PSRGRQPG----TS-LPGAGPSMSE--A-EYP--GDG
DNLVDPLLLTSQDQPLLLVDWPKSLLSRAIFHSYTSS-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXPHGL--EAH-IFSVFCMSGD-DFRY
EFSYRIGNSP-KHTLYRGRDTQYYFALPGGEPSNNYKXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-----XXXXXXXXYNSSLENLSTLQLMGSSLEIRNYVTMLTK-VLSRWVKEDG
SS-LCVQWPQMQDAFISSVCRLTLTNQXXXXXXXXXXXXXXXXXXXLSFMSGVLILKYAQ
TLLTQS---QSLGKFMMDKSFASELIFLV-SGVLEVSDKEKSRN-VNYLRGEGTKIISDL
LLSCLCLNEEHGFHVSTGQMEFLALLHHNQQSSVQNLGSVQVHLPADVA-GLSPAGTEMQ
SPCYVSHLMFFKKNLYGEGQAPG-QTGQT-VALSLFNCSSRRPISRQRLKKPVTVEFGAF
GEEDLDSQRNKTAFVLLRDKVNFHKFT-GFSEKHLESLQMRIEFSKPIARAFPVLLLVR-
FSEKPTPSDFLVKQIYLWDGHVVHIHIPAALRKD-------TSSGYLSMLDADYDRKPQN
KYFAEAVNYTVHFQWIQCLFWDT-KGWKSERFSPQPGTSPEKVNCSYDRLA-AFTIARRQ
LNASFEVSDISKLQRHPENLLPSTLMVVTVILYALLATKSRQVDLREKKKMGPIFLQENS
P-GDR

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2038)

QLYAVVIDTGFRAPARFTAKVYI---VLCGENGISEPKELYSPEK-PLFE-----
-SNSRHTFILRAPARLGPLRTLRLWHDNCGACPAWYISHVMVEELHVG--RGWFFPA

ENSGT00700000104221_7_Linker_6_7 (2038, 2667)

ECX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXLPLGVDP----TFSSFQMGFLLTLLASPGAQLLSLLF
RLSKXXXXX-XXXXXXX-XXXX--XXXXXXXXXTNS---------PGR-IPDTWET---S
QKPPSSALAGSTGTHRVVAS--------------ADP---VSS---PQ-LDVCRGESS-Q
SPREKS---NRHPQFTQVP--GMSSEGLPTPQKSWAPLPWLGSAAWLICGTVSVACGVGT
GLLGYRFRPEQCVQWLHLLASSMLCCALHSQPLLXXX-XXXXXXXXXXXXXX--------
---XXXXXXXXXXXXX-XXXXXXXXXXXX----XXXXXXXXXXXXXXXXXVLATRQRARR
LRQCKVHPPSEAQLRAPRARMRRQIGAQQALR--SISMYLLMLLLFLVIVYGKLSQG-EY
FLNQAIRNEFTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRALGGK
CSLLGTLTIRQLRHHPESLCKLPSSLSAPTQDSLSTCNPTV-EDPETPLVTDPEAARVG-
---Q------SDLG----SAR-EDCE

PF08016 // ENSGT00700000104221_7_Domain_7 (2667, 2857)

LNLGNTRP--ASRDTLTKLRASGWIDGSTRAVSL
HFSLYNPPTRLFSSVSLNAELLPEGGLTFSPLVESFTIFPSDSSPRYHL--------ILT
E-LLFLVLSVIHFCFECYDMIEKGTCSYWRKPRSWLKVSIVGVSLAYLAASSYRATLAGE
VTDQFQKGCFQGFTDLSHMALWNQRSRWLQGILSFLLMGKCVCLLGIQKTMAPGSF---K
MGNSFS--SIFTPGLIGVLTLAVHHCL-HRFLL-STGALPS-GTLADTFRD--LPFQFPG
RSQNPSFLSL---SRSDQQAAAWCY--GVLSIAVAILWFGM-------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

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-----------------------------GIYMIKVIIFSELHGNEKELGPYYVEISQGD
LGAFMNSSSVHKDEVLLFASSFPRRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXVSIFTNGTMFATDSEVTFFVLTNETSPLEFVWHFGDGSWERTTSRSVK---KR
YSIPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXEGEFTVEVLIFNSVSFATLKKQVFIVPQPCQPPL
VKNMGPGRVQIWRHHPLKLGVTFEAPIQCDISQGLNYSWSIIKSDGSQVLFPTALDNHRQ
AILLPSYFLEYGNYTALAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---
XXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPL--HISWVNFKDNSVNW
NEEFSLQVKCEECTNMLNVSYSWDLFLINATETNGIEVSFCRAPDLLGSSSLTGAMLTIP
KSSPPSTE------------TNDPA-LTTTPFPRDASGQAIRQLALSAPVETSISATSIN
ITIGFHQIPVTGRAAVLE-----DPVQE-GLLYPMQDLLQKKSVIIHPE------RNELP
--QNSSYISDFEAYYSNIKEAIEPGRGRQPGG--SIS-I--------------TE--EDG
YNLIDLSYSTENTAPLLMVDWSKSLISRAIFQSSTSS-XXXXXXXXXXXXXXXXXXXXXX
XXXXXSS--HSPLGKAQLYFTVNDVPKEMACQVQPIHGY--EAYTVFSVFCMSGKVDYQY
EFSYQIGESS-KIPLYRGRDIQYYFTLPAGEAVDRYKXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-----XXXXXXXXYNSSLKNLTTLLLMGNYGEIRNYIIMLTR-ILNRFYTEDQ
SS-TFGLQSQLRNLLISSVCNLSFQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXXXXXXX----X-XXXXXXXXXXXXXX-XXXXXX-XXXXXXXX
XXXXXXXNYVFSNYISTGQLEFQTSLHFTFHSSVERVGSVEVQLPDTLD-EHFSGSMGLH
SQCYISQLIYFKEHPYLEQRLPV-EXXGA-VGPGLYNCTSKRKINIQRLESPLGVVFEN-
-SSAQDDGQNKTIFSLYRDKVNFHYFS-GFPEASQESLQIVVEFSKINIRTFPVMLLVR-
FSEKPTVSTFNMKQICSWDEHVVQIYIPAVSLKD-------ASSGYLALLDADYDQKPTN
KYLANIVNYTVSF

PF01825 // ENSGT00700000104221_7_Domain_5 (1814, 1858)

QWIRCLFWDENRGWMSEGSYPQQGITPQTINCSYNHLT-TFTVVRRK
LNVSFEMNDVSLLKSIPHNLFPSILVVFFMLFFAFLAIASKRRDLHEQKKDGYIFLQENS
QARDEQVYVVIIDTGFRAPAQLTAKXXX---XXXXXXXXXXXXXXXXXXX-XXXX-----
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXLLYSIFTEYLEDFHMWISVYSRPSYSCFTHTERLI
VSFFLTLGYMSINAXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX---X
XXXXX----------XXXXX--------------XXX---XXXXX-XX-XXXX----XXX
XXXXXX---XXXXXXXXXP--CNELEES-APQKLMVFPPWLSYVSWVTCGLISVACGLVT
GLLGYRFGPSKCIQWIHSVFFSVIGCTFVTQPLVIFF-VALALAWKKRDHKG--------
---FFIEALYDATKNL-EYELHHLSKNHA----LYPSYCCTPSTAADFEKILVARQRARY
LQR--VHPPTSAQLKEARGRIRKEVLLQTALX--XXXXXXXXXXXXXXXXXXXX-XX-XX
XXXXXXXXXXXXXNTRNFIEVKNADDWWNWSLTTLLDGLYWS------------GPLGGK
CHLIGTSVIRLLKVSRN--------XXXXXXXXXXXXXXXX-XXXXXXXXXXX--XXXXX
XXXX------XXXXXXXXXXX-XXXXXXXXXXXA--KAYSVLINLRNSGWINKSTKEISM
H

PF08016 // ENSGT00700000104221_7_Domain_7 (2702, 2844)

FSLYNPPTKLFSSVSLLAEVLPTGDFITSSLVESFSIYHSHSARTYSI--------MFS
E-LVFLVFNLIHLCFQVFSMIQKGILNHWRNSWNWLEMCIIGVSLSFFAHSIFHFILVVD
VIDQFHKGFFQVFVDFAPILSWHQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X
XXXXXX--XXXXXXLAGILFAAAYSYL-GRFLF-STHAFPF-RSFADAFQM--LLLCFLG
TNKKGTFFSL---YKSDQYTTVYYY--GTFFIAVIFLWSGIXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXDF-YLD-EFESLLDELLLRVNGLY
YNLHCSSLEKPPS-----DQAGVE------------------------------------
-------------------

------------------------------------------------------------
----------------------------------------------------------AP
----------SILDDQDRCLQAAHQNP----RSAEERGGLHLCSHT--------------
--EVQVGVPAKHVHLLSERKFSCPPGALRGMTGD---------------SATQRPSPPAS
GEQDGKTPVSLDWSTSA----------HSSHSRLPGPC---TTSVSEAQPGPERSCLLTR
RPPGPIPVQDPSHAVNPVLHSFPEAGVQAPLPLGFHVHLASPAAVCLTLDFGDSSGVEIR
LNNASEAAVATAYHQYGTXXXXXXXXXX----XXXXXXXXXXXXXXXXXX-------XXX
X---XXXXXXXXXXXXXXXXXXXXXXXXXGVYMLKAVIYNEFHGAEVELGPYYMEVSQRN
VSVFLNSSSVHKDEALIFTGSSVNPESTVVVHRFSPSSSYNVSFISQTQVGDSQAWLSVT
IRYKMQPVS

PF00801 // ENSGT00700000104221_7_Domain_0 (550, 629)

VYTNGTVFAADTDIVFTAVTKETTPLEFAWYFGDGPPVRTTLRIIK---KR
LSIPQRYHVTVRAASRLSSVVSEPHLIT

ENSGT00700000104221_7_Linker_0_1 (629, 639)

VQKKIIANRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 711)

MSAPSALVNTSVTFECRINFGT
DVAYLWDFGDGTVSPGHS-SSHVYSREGEFTVEVLAFNNVSTAILKKHLFITHEPCLPPL
VKNMGSGKVQIWRSQPMRLGVTFEAAILCDISQGLSYTWSFMDSEGSPVPLPAAVNTHRQ
TIVLPGYLLEYGNYTALAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---
XXXXXXXXXXXXXXX-----XXXXXXXXYYWTCMAASMPGQPCFHDSA-QFLDSGAPTIS
FPVSWLSHSYDQFLVTLTVSSGDRNSSEAQVFLSTRPEPAFRFV--HITWVSFKNIFINW
NEELSLGAVCEDCAELPHLSYSWDLFLVNATERSRTEXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX
XXXXXXXXXXXXXXXXXX------XXXXXX-XX------XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXFEAYYSDIQRAI-PSRGRQPGS--NTS-LPESGPGAN---AEGHPGEGDG
DNLVDPAFSEGRAVPVLMVDWHKTLVSQAVFQGYTSL-GITGQTVTIKPYSLSPGETYVL
QASVGSR--QNLIGRAQLYLTVNRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDFLY
KFSYQIGNVS-KHTLYHGRDAQLYFALPAGEPSDGYKVLVSTEITDREGSKARPCAVAVT
VLPRYRG-----DDCPAGEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXDEMTDSVLMLKGLVNSPNKXXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX-XXXXXXXXXXXXXXX
XX--XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-XX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXHPQNLFPSVFVMVSVIVYGLLVIKCRHADRHEEKKTGYIFLHGDA
L-PDRQLYAVVVDTGFRTPARLTSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
-XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX--XXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXLPMGVTPTAV-TAASFRLALLCSLLASPGAQLLSLLF
QLSKEDSRP-ARAQLHS-PLREAQA---EATL--GPD--------SSGRLSGPQEP---C
QHPPSAVPSGSARARRKAA-D-------------S-SG--MACPH-PE-LEAQEADHCQS
SLREKS---GPHSPCSQAP--SSGLEGLV-AQQLKARLPWSDFAAWAVCGTVSLACGLGT
GFLGYRFGPAQCEQWLCLLSLSLVCCVFVTQPLMICI-VALGFAWKRRDDHH--------
---FFTESLGEATRNL-DSELEGLARMPF----ALSPHRCLPECAGQARQXXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX--DISLHILTLLLFSFIIYGTYPRE-EY
SLNQAIRKEFTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXXXXXX
-XXX------XXXX----XX--XXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXX
XXLAFLVLNLAHLWFQLYNLIEKGGLNYWRKPRNWLELSVAGVGLTYH------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

---MA---EEAAQNISGDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMRDGKCDCPRCALKTKAEDRESQSPSSLPSGQKNIWKTTSKAVLSVVNE
KTQAVVNEKTQAPLDCDHSADRIPHKPSIIIARVWSSGGPRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAAPCSLKMEASCCVLRLLCCAEATAMGL----LPGTVSMETPTEVARPTQ
TSS----KRVPLWLIS-----HFPTSPRSSHSLP--PGTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQNSDNSMNSVLDCSPEMEARAPPNLGFHVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVIF-FLLLHFQLDISTYKE---------------------
-------E---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTKVELGPYYVEIGREA
VSAFMNSSSVHEDEVLVFTDSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSVT
VWYRMQSISV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDITFTAVTKETIPLEFQWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTISLGSSSSSHVYSREGEFTVEVLAFNNISAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCEPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYIWNLMDSEGLPVSFPAAVDTRRQ
TLILPSHTLEYGNYTVLAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDPD-----NPGATLRYHWECTTASSPAHPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFINW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTVHPD-ATTTPFSREPSLVTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPSPHLSDFEDYYSDIQEAI-PSGGRQPAK--DTS-FPESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPALMIDWHKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLAVNPAPRDMVCQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLAEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCHQWSRIQDALISSVCKLAFVDQVWPRGGQEMRPR---------------------
-----G---PASSVPIHGCGLSGQLIYITNECCWFIK-----------------ERMTKS
IIGCLPLN-----HVSTGQMEFRTLFHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGPDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------VNVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVTCSYDRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGLLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNRLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGHVERELTCLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFTLLCIYACLTALVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAKPHC-PPRG--EAQAEAPQVPNS---------CRR-IPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSGT
ALMGKS---HCCPPCTQAP--NSGLEGL-MPRWSRAPQPWWSSAVWAICGTASLACGLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSRTRL----PFSSSCSIPDYAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISMDILMLLLLWGIMYGRFSQD-EY
SLNQAIRKEFTRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPRPFSVPIEDSIPTCSPEG-GGPENPYLIDPENQNVTL
-NGP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2897)

VLSLGRTRS--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSMEILPTGSLVPSSLVESFSIFRSDSALQYHL--------VLP
Q-LVFLALSLVHLCVQLYHMMDKGFLSYWRKPRNWLELSVVGFSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCIYLPGIRNTMASCSS---M
TRHSLP--SIFVAVLAGALMLAALSHL-RRFLL-TMWALPS-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYL--GILLTVSATLCFGMVSKHVPNFQ----------
-----------------------------VMVCKSFNY-YLD-EFANLLDELLMKINGLS
DSLQLPFLENISN-----SIGQARAEESPLVDIS-SKQATEVRPCKIIYVNFLYSNLSSK
GVLEYLLFQIIRSICINIL

-----------NLPPFTLSLRSLPAACSLCLPGQAPESAEERGGLHPCCCSHSPPRGGAG
VE-VRASHVCFMSDEKHGCPPSASQGLEGDQDAQDPRPSASREKNILKTASKGVLS----
-----VNGKTEASLDWDGGANRFPCAPSVTISSVWSGSGPRSCHWRLCAAGKADRTFFGL
LQ-VQGSSSAAALCSSKTEASCCVLGLLCRAEGMARQR----LPGTTTMGNPTTAAGPAR
TST----QRAPLWPISHFPTFPR-----SSHGLP--PGTSHTPSLSESQSGHKRLCPLIP
HPPGAVPAQDPDHAMDCVICHFPETEAQAPPNLGFRVHMASAVALCLTIDFGDGSGVEMR
IHNMSEATVVTAYHQYGTGRYSTL---LDS-----QYFKL----------------CS--
-------------RLQTSQSEIQAVDPSNLFYVLKAVIYHEFPGAEVELGPYYVEIGHEA
LSVFMNSSSVHEDEVLEFLGSHVNQKSTVVMHRFPSIPSYNVSFISQARVGDSQAWLTMT
VWYKMQSISV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 621)

YTNGSVFAADTDIVFAAVSKETTPLEFVWHFGEDPPVRTTSRSIT---KR
LSIPQWYRVTVEASNRLGSV

ENSGT00700000104221_7_Linker_0_1 (621, 643)

VSEPHLIRVQKNIVANRLLSPP

PF00801 // ENSGT00700000104221_7_Domain_1 (643, 704)

SALVNASVAFECRINFGT
DVAYLWDFGDGTFTAGSRSISHVYGREGEFTVEVRAFNNVSTA

ENSGT00700000104221_7_Linker_1_2 (704, 752)

TLRKRLFIVRKPCQPPL
VKNMGPGKVQVWRSQTVRLGVTFETAVLCDI

PF02010 // ENSGT00700000104221_7_Domain_2 (752, 1407)

SQGLSYTWSLVGSEGSPVPLPAAVDTHRQ
TLVLPSHTLEYGSYTALAKVQVGGSVVHSNYCVGLEVRARAPVSVISEGTHLFIPRA---
ASPPVVLRGTQSFDP-----DNPGATLRYHWACTAASSPGRPCFDSSAPHRLDTRAPAIS
FAAKWLSDRYDQFLVTLTVSSGGRNSSEAQVFLSTRPDSAFRFV--HISWVNFKDTVVNW
NEELSLQAACEDCGEIPNLSYSWDLFLVNATEKNRMEVPFCRTAGLLGSLGL-GAILKLP
EPSPLSAGP----------SPADPD-VTTTLFSPELSPKTLGRPALSALG-----RTSAE
HTAGAPQIAVIGDSKVPG-----EAPKE-GPPDPEPGSQGERSPTTSPS------ERSRL
PTSPARPLSDFEAYYSDIQEAI-PSEGRQPGN--SSS-LPGSEPSLSA--EEESP--GKG
DNLVGPSLPQDRAVPVLLIDWPKALVARAVFQGYTSS-GLTERTVTVKPYSLSSGETYVL
QVSVASE--HSLLGKAQLYLTVNRAPEDVACQVQPHRGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYHGRDTQYYFSLPAGDPSDNYKVLVSTEIVDGKGSKVQPCAVAVT
VLPHYHG-----SDCLDQDLYNSSLKSLSVLQLVGSRTEIRNYIAMTTE-ILRRLSEEGG
TA-SCGQWSQIQDALISSVCQLAFADQEEMTDSVLMLRNLISFSNKLSVESALLILEYSR
TLLAQG---WFAGRCVADRGLRLELVLLM-SRVWDVSEQEKSQS-EDYIREEAIITISDL
LLGCLSLT-----HVSTGQMEFQTLLHLNLQGSVQSLGSVQVHFPGDLA-RHSPAGAETQ
SPCYISQLILFKKSPYPAGRAPG-QIGGV-VRLTLYNCSGRRPISRQWLRKPLTLEFEE-
-EDNPDHRRNKTTFVLLRDKVNFHQFI-GLSENSQESLQIEIEFSKPISRAFPIMLLVR-
FSEKPTPSDFLVKQIYFWDEQIVQMYIPAVSRKD-------ANIGYLSLLDADYDRKAPN
KYLTKAVNYTVHFQWIRCLLWDK-KDWKSGSFSPQPGTSPEKVNCSYDRLATAFSVLRRR
PNARFEVSDVSKLQSHTENLLPSIFIVVFMILYGFLVAKSRQVDRYEMKKTGYIFLQDAR
L-PGHEL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2045)

YAVVIDTGFRAPARLTAKVYI---VLCGENGLSETKELYCPEK-PLFE-----
-RNSRHTFILSAPGQLGPLRKIRLWHDSRGPSPDWFLSHVMVKALCTG--QAWFFPAQCW
LAAS

ENSGT00700000104221_7_Linker_6_7 (2045, 2666)

RHDGRVARELTCLQGGLGLRKLFYYKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLA
MTFALLCVYACLAALVTAGGHEQVGASLPYRGF-Q-------------------------
-------------------------------------------------P----------
PDRQCAILSG--DTWRKAAS--------------GDS---AACAA-PE-LGA----CGGT
AASGHS---CLCLPRSQAP--SSGLEGL-TPP-PAARLPWSDSAVLVVCGMASLACGLGT
GFLGYRSGSRLCAGRTQTVRVTVLSCA----SVQIGL-MALGFAWKRRDDNH--------
---FFAESLCEATRNL-DVELEEHSQTYF----PLSSSCAVPGRAGEVEKVLAARQRARH
LRW--AHPPSMAQLKVTRERMRRESRRQAALR--DISMHILMLLVLLCAIYGRFSQD-EY
PLNQAIRKEFTRNARNSLGGLRSVADWWDWSLTALLDGLYPGGASAASKPGTQVGFHS--
------------LFTGDHLGKPPRAFSVLIKDSLPTCSPEA-GGPESPYLTDPEKPNMTL
-GGP------GGCG----AR--EAC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2790)

VLSLGRSRS--EAHAALAGLRASRWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGGLVPSSLVESFSIFRGDSALQHHL--------MLP
E-LVFLVLNLVHLCFQLYGMVEKGVLIYLQKPRHWLEVAPLSFVKNNN----------NK
VPQ----------------------------------------------AVPRSSE---A
VARSVT--RLFSLQLAGALALAARSHL-RRLPL-SSCALPA-GTLAEAVPG--LLFCFPG
RSPKDLFLGL---AQSERRAVACYG--VALCAVTAALCFGMLRGSLMTLTRRR-KSFQSK
CPVRLKDVAAYTWGKALTVLGLEIPKLDETEAVENHNY-YLD-ECENLLDELLMKINCLA
DSLQLPLLEKQSN-----GIREA------RVGIS-SYHAAEVRLCKLIYVSFLYSKVLKF
-------------------

---MPDPHRLEEHALRAASEQCLQDACCLSFCGEMPVSTDKSWGLHLCSCS--PPGGGVW
VCKVCANRVLLMSDEKCGCPQCALNRKAEDRESQSPSSLASGEKNIWKTTSKAMSSVVNE
KTQAVINEKTWAPLDGDNSADSIPHKPFVIIASAWSSSGPRFHHRRLCAAGTTGSTSSGL
LQ-VQGTSSAAAPCSLKMEASCFVLRLLCCAEDLASGL----LPGTVTMETPTKAARPIQ
TST----HL---------------SLSHSSHDLP--PGTSQTPSLTASQPGPESFYLPTQ
CPPVALLAPNPDDSMNPVIDCFLEMETWAPPNLGFRVHMASGKAVCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVHSV--------------------------LIRIYLYQNE
NS---CRE---DSDPSNLGSELLYAFVTR--MFLKAVIYNEFHGNEVELGPYYVEIGHEA
MSVFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISPSQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDITFAAITKETIPLEFEWYFGEDPTVRTTSRSIK---KR
LSIPQWYHVMVKASSRISSVVSEPHIIRVQKKVVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSFSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCKPCQPPL
VKNMGPGKIQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISQGLSYTWKLMDSDGLPVSLPAAVDTRRQ
TLLLPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVQAQAPVSMISEGTHLFFSRT---
ASSPIVLRGTQSFDPD-----NPGASLRYHWECAAASSPGHPCFSPSTAYQLDAGAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPHPDSAFRFL--HISWVSFKDTFVNW
NDELSLQAICEDCGKMPDLSYSWDLFLVNATDKNRIEVPFCRVVGLLGLLGL-GAVSMSS
QSNLLSTEP----------GTADPD-ATTTPFSWEPSPTTRGQPAPSAPR-----GTPTE
PMTGVYWVPAAGDSAVPG-----EAPEE-GSLDPEPGPQSKGSLMTDPS------ERSQL
THNPDPHLSDFEAYYSDIQEAI-PSEGRQPAN--DTS-FPGSGPSLSA--K-ESP--GDG
DNLIDPSLSAGRAKPVLMIDWPKALLGRAVFQGYSTS-GITEQTVTIKPYSLNSGETYVL
QASVASK--LGLLGKAQLYLTVNPAPQDMACQVQPHHGL--EAHTVFSVFCMSGKPDFQY
EFSYQIGNTS-KHTLYHGRDTQYYFVLPAGEHLDNYKVTVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCSQWSQTQDALISSVCKLAFLDQEEMTGSVLMLRDLVSFSSKLSFMSAVLILKYTR
ALLAQS---RFSGPFVVDKGVWLELISLI-SRVWEVSEQENSKD-EGYLREEGITVISHL
LLGCLSLN-----HVSTGQMEFRTRLHRNLQNSLQSLGSVQVHLPGDLA-GHSPAGAGTQ
SPCYISQLILFKKSPYQGGQVPG-QIGGV-VGLNLYNCSSRRPINKQWLRKPVMVEFGQ-
-EDGPDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPIMLLVR-
FSETPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPDKVNCSYDRVA-AFALLRRK
LKANFEVSGISKFQSHPENLLPSIFIMGSMILYGILVTKSKQVDHHEKKKAGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2041)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGRSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKICLWHDSCGPSPSWFISHVMVKELHTG--QGWFFPAQCW

ENSGT00700000104221_7_Linker_6_7 (2041, 2666)

LCAGRCDGRVERELTCLQGGLGFRKLFHCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVTAGGQEQPQLDVSP----SLESFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-VRTEPHS-RLRG--GAQTKAPQGSNS---------CRR-ISDAQEP---C
KHPASAILSGSGRAQRKAAS--------------DNG---TACPA-PE-LEAHGADHSGT
ALMGKS---HCCPTRAQAS--SGGLARL-MPQCSRAPLPWWTSAVWAICGTTSLACGLGT
GFLGYRFGQEQCVQWLQLLSLSVVCCVFITQPLMVCL-VALGFAWKRRADNH--------
---FFTESLFEATRNL-DSELAERSWTCL----LLSSSDSIPDCAGEIEKVLAARQRARH
LRW--ARPPSKAQLRVTRQGMRRDSRTQAALR--DISMDILMLLLLLCIIYARFSQD-EY
SLNQAIRKEFTRNARNSLGGLRNITDWWEWSVTTLLDGLYPGGSPSTRVPGAQPGALGGK
CYLIGSSIIKQLKVFPSHFCKAPRPFSALIEDSLPTCSPKV-GGLEKPCLIDPENQNVTL
-NGP------GGCA----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2895)

VLSLGRTRS--EAHTALSRLRASTWIDRSTRAVSV
HFTLYNPPTRLFTSVSLSVEILPTGSLIPLSRVESFSIFRSDSALQCRL--------VLP
Q-LVFLVLSLIHFYVQLHRMMDKGVLNYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCHAFMDLTLMASWNQRARWLQGILLFLLTLKCTYLPGIQNTMASCSS---M
MRHSLP--SVFVAGLAGAPVLAAISHL-RRFLL-SMWAPPP-GTFTDAFPR--LLFRFPG
RSQKDSFLGL---SKSEQRDMACYF--GTLLIVSATLCFGMLRGFLMTLPRKR-QSFQSK
SLVKLKDVTAYMWEKALTFLRLKAPKLEEAEMVENHNY-YLD-EFANLLDELLMKINDLS
DSLQLPLLEKTSN-----STGEARAEESPLVDIS-RYEANEVRPCKIIDINFLYSNFSSK
GVFEYLLFQNIRSICINIL

-------------------------ACCLSFGGEPSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHMLLMRDGKCDCPRCALKTKAEDRESQSPSSLPSGQKNIWKTTSKAALSVVNE
KTQAVVNEKTQALLDCDHSADRIPHKPSIIIARVWSSGGPRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAAPCSLKMEASCCVLRLLCCAEDTAMGL----LPGTVTMETPTKVARPTT
T--------S-----------------SHSHSLP--PGTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQNSGNSMNSVLDCSLEMEARAPPNLGFRVHMASGEAVCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVIF-FLLLHFQLDISTYKEAETK-----NMTLKVFLCQSE
NS---CQE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTKVELGPYYVEIGREA
VSAFMNSSSVHEDEVLVYTDSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSVT
VWYRMQSISV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDITFTAVTKETIPLEFQWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTISLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCEPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYTWNLMDSEGLPVSLPAAVDTRRQ
NLILPSHTLEYGNYTVLAKVQIEGSVVHSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDP-----DNPGATLRYHWECTTASSPAHPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTVDPD-ATTTPFSREPSLVTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGPLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPESRPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPALMIDWRKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLAEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCHQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLSFMSAVLIFKYTR
ALLAQG---QSSGPFVIDKGVRLELIGLI-CRIWEVSEQGNSKE-EGYLHDEGITVISDL
LLGCLPLN-----HVSTGQMEFRTLFHYNLQSSVHSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGPDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLRIEIEFSKPGTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDEPIVQIYVPAASQKD-------VNVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIQCLFWDK-REWKSERFSPQPGTSPEKVTCSYDRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGFLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSCGPSPGWFISHVMVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSHYLHTPRLT
VSFTLLCVYACLTALVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAKPHC-LPRG--EAQAKAPQGPNS---------CRR-IPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSGT
ALMGKS---HCSPPCTQAP--NSGLEGL-MPRWSRAPQPWWSSAVWAICGTTSLACSLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADSH--------
---FFTESLREATRDL-DSELAERSWTRL----PFSSSCSIPDYAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISMDILMLLLLLGIMYGRFSQD-EY
SLNQAIRKEFTRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPRPFSAPTEDSIPTCSPKG-GGPENPYLIDPENQNMTL
-NAP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2897)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLELEILPTGSLVPHPLVSHSASSAVTQALQYHL--------RAS
Q-LVFLALSLVHLCVQLYHMMDKGFLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCIYLPGIRNTMASCSS---M
TRHSLP--SIFVAVLAGALMLAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYL--GILLTVSATLCFGMLKGFLMTLPQKR-KYFQSK
SLVRLKDITAYMWEKTLTFLRLETPKLEEAEMVEYHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENISN-----STGEARAEESPLVDIS-SKQATEVRPCKIIYVNFLYSNLSSK
GVLEYLFFQIIRSICINIL

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------AVS

PF00801 // ENSGT00700000104221_7_Domain_0 (550, 629)

IVTNGTFFSTETNIIFKAVTSESGPVHFVWNFGDKSLPESTYNSV--ISKK
YSIPNSYNVIVNASSPVGTVVSEVYTIF

ENSGT00700000104221_7_Linker_0_1 (629, 640)

IQKKVIPNRLI

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 711)

ARPSVLINSTVTFECRINSGT
NISYLWNFGDETIRFGKITDTHVYMREGEYTVNVSIFNNVSAAFLTKQIF

ENSGT00700000104221_7_Linker_1_2 (711, 742)

VVRELCLPPP
VKHMGPQKIQIRRYEQLCLGV

PF02010 // ENSGT00700000104221_7_Domain_2 (742, 1255)

TFEAEIMCNISQGLHYFWSFVKSNGNSVILPNYINDRKQ
KITVPGFLLEYENYTAVARVQIVGNVVYSNYTVLLEVLPSDPVSVIAGGTHFLIDKS---
TVTHFKLDGSASFDP-----DYPEASLRFHWKCIPVSLYSDSCFNTAALNPLQTDGSIIH
FPTALLNEKFDQFLISLTVSNGNHRSPVAQTVLSYSENSAFPFWDVQIICIECKGYTVNW
NEKLSVQVVCTECREA-EISYSWELYSINTTEVESSDGPFCSVLEILGSSSL-FGTPLP-
-SVEIFTDPPITQIIS-GDIFDEHRLTEEAYLRLDPCPKTVP----------------SA
PIHGIHVCPRFYSTAHVQNA-RHQGKIDFS-GG------GEGGA-------DLFNLTEVP
THSVDNILADLEVHCIGIQEGKKGSGGRPEDP-EGER-YGSTRPH------E--NEDQKG
DEILNPSKAAAVSPVTSMLDWKTQQISKSTFRGFVTT-DLSSQVLTFKPFSLKPGKMYML
DVSLAAS-RGNEIGKSQLYFTVNEMAPRMTCQVQPNEGM--ELYTVFSIFCTSGKEDLYY
DFSYQVGRRSARKKLYEGRDIQYYFNLPAGDQTDGYQVTLFTQITNMYGSQTKPCPVNVT
VWPSFGKNTS--TDFIAEQLYHHGLKNLSVLLLMENHIEIRNYITLLTV-VLNKLYSEET
KT-PFELQSKIRNALISALCSMSFQDEDEFDEIVSMLIDLLNYTKQVTAKSAILVVNATK
KILKRSVDSEDHSRIYLQRNSVEKIVSLI-SYSMEVSIGYNE---RNFIVLDGMNIISDL
MLGCLSLK--QHLGLSTNLIDFQTSTHMMLQNSIQTIGSTKVYLPQLQS-SH--LETKLS
NRCYISQLVYFKKNPYLWAEISSQLQGEF-AGVSLFNCSNKKKINAREIAAPVMMEFDM-
-KRNHDLELNKNLFSLYWDKVNFHRFH-TVSVNRDEALLITVTFSRPNLRAFPVLLLVR-
YSDKPNTSHFNIKEIYTWEGNSVQIFIPAHSIKD-------GDNPYLAIMDADYNRQPRN
KYLSKMINYTLETQWTKCLYWDYYKQWNSESCFPQKGTLSTNIICRQHNFI-CIVSLCNW
HSNSMQLNALCMIQRTTKNVIPCTFVLLTVFVYTLLAIYYKFKDRHEEKKNGVVFLQDNS
P-NDH

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2057)

QHFAIVVDVGLRSRPKSTAKVYV---VLHGEDGVSETRELYFPDK-PLFE-----
-KNSRQAFVMSVSESLGPIWKIHIWHNNSGYSPSLYLSHIIVKDLQSG--HSYFFLAECW
LAMDEGDGKVERELTS

ENSGT00700000104221_7_Linker_6_7 (2057, 2535)

AVHGLEFKKLFYCKLTELLEDLHLWGSLFSRPSYSCFTYTQRIT
VCLVLLLGYMFLNSVLIHWEEEQHSFEHGLLDV-SPVSMISGFQSTLALYPLAALISLLF
RFSEKKLTSDSGVSRHT-PLKVTHFTQCK----------------ATLLTLGRFASVQNP
EQPRSSFDLYTTSGYSRTGKR------------SKKG------SPSPTIQSSSGFEDCSQ
HLAQKNCSHSSCDTCSEFPTEFSGHRSLF-GNQYKVLPQWCIYLAWCFCAVISIVCAAGT
TLIGFSFGPTKCILWAHSVFFSVIFCTFVVQPSTXYIIIAFFMTWRKKEIID--------
---LFAETVCEATKYF-QRETSTFE-----QISTLHSCPNDLDISTDFEKILAARKRARY
LRL--ARPPSPSQLKVVKDKIRKKTTTEKTFR--ECFMHGIMILIFLFITLGKCSND-DY
LLNQAVRNEFTRHA

PF08016 // ENSGT00700000104221_7_Domain_7 (2535, 2993)

KQSFKNIRTEDDWWNWSFNVLLDGLYWNKMYNITSAKSKTGPIGGK
FFLIGTPIIQKFSLENSSACVVTVIYKSYSNNAANICSTGGYTGIKNHYLHEKSNSLNVL
--AS-----TAVCS----TTVSLISSSDISLIRT--EAYSALLRIQSQQWINHSTTALHV
LFTLYNPPANVFTVVLLQMEFPASGGVITSSLIESFKIYHIATLLDYIT--------MAL
K-LLFLGLILLHSCFQLGVMIQTGIRNYWQEPWNWIELGIIASSLCYYACITYTFLLTMD
MIDRLQKVFFRIFIDCSILAAWEKWNRSLHGIIFFLMVIKFIKLFRIYKVMAPCLTV---
LHLSS-------SKISGIIFSLAFSSLGHVIVL--FNSFHF-SNMIRSLHM--LFMNLLG
VGDRRLFSFLHLRTKSVPLPATCVY--VVLFLFITILWTGMIRGILTSIMKNTSKIHRNK
QLITLTDVASHAKEKVYSVFGRQRMKSTDTTTFPRNNF-YLE-EFEDLIDELLFRLNAIS
NSLHHSLPAKLHC-----YTEEAEEDKRPAFTIKMHM---AVSPFSLALF----------
-------------------

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-----------------------------------SPHSSLSHSGSASWSRPKQLCPLAQ
CHPGAISVQVPADAVDPTICDFPGTDAQAPPSLGFRVQVASQAPLCLAMDFGDSSGVQVT
IRNVSGGMAVTAYHQFGKE-----------------------------------------
-----------------------------GVYALQALVYNEFCGTEKELGPYFVEIGPAT
VSVFMNSSSTHKDELLAFAGARTGQKGTIVSHRFPAGPSCDVSFTSQSGAGGGQAWPRVT
VRYHMQPVSVYTNGTVFATDAHITFLAVTEETTPLEFVWSFGDGLPTQSVPHL--PCPPP
RRPHRRYSVTVRAASRLGSVASEPRRIRAQRRIVASRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 711)

ASPSSALLNSSVAFECRLNFGT
DVTFLWDFGDGTVGLGDSSASHTYSREGQFTVQVLAFNEVSAASLRKQLFVVREPCQPPP
VKNMGLGKVQVWRSQPVTLAVTFESAILCDISQGLSYTWTFWNSQGWPVALPPTVSTHRQ
MVTVPSYFLEPGNYTALARVQVEGSIVHSNYSLAVEVRARAPISVISEGTHLFISRA---
PAFTVVLTGSQSYDP-----DCPGAALSYHWKCTAASSPGHSCFATSSPRSLDAGAPSLA
FPADSLSDSYDQFLVTLTVSSAGRNSSEAQVFLSPRPDSALRFV--HISWVSFKDVFVNW
NEELSFQAECDDCGEGPHLSYSWDLFLVNATERTRMEVPFCRTAGLLGAAGL-GAVSKLP
ESSPPSTEP----------SWLEPH-AMGTPSSREPSPQTQGQPVLSAAR-----KPSSG
PKVGRHWVPAMVEPGPP-------------------------GSSSL-------------
-QSPSPSPSDFEAYYSDIQEAV-PPRGRQPADWANAS-LPEAGSSLS---AAGGH--RDG
DN-------------LLTVDWPKSPVGRTRFHGYTSS-GITGHMVTIKPFSLSPGDTYVL
QASVASP--HRVLGRAQLYVTLNPAPQNVACQVQPHRGL--EAHTIFGIFCMSGRPDFRY
KFSYRIGKAS-KRTLYHGRDSQYYSALPAGERLDGYEVTVSTEITDGTGSQVPLCAVTVT
VLPRFHG-----NLCLDEDTYNSSLKHLSTLQLMGSYTEIRNYITMMTR-VLTRWAAEDR
SP-SCGQWSRVQDALISSASRLPSADQQEMNDSVLMLRDLLRFPHKLSFKSAVLILKAAR
ALLAQN---LLSGRLVVDEGPMLELILLV-SEVLEASDQEKPRS-AGYLQEEGIKVISDL
LL----------LHVSAGHMEFHVLLHRDLQSCVQSLGSVQVHLPADLA-GWDPAGVEMQ
SPCYISQLVLFKKNPYPGGRAPG-QIGQV-VAPSLFSCFSRRPISRWRLREPVTVEFGE-
-DDGLDNI-DKATFVLLRDRVNVHQFF-GRSANPQESLHIRIEFSRPVSRAFPVMVLVR-
FSEKPTPSDFLVRKVYIWGEQTVHVYVPAGPLRD-------TNMGYLSLLDADYDRSPPS
KYSVQAVNYTVRFQGVQCLFWE-ASGWSSASSSPQPGASPEKVTCRYRRAV-ED---KRG
TLRGFTIYSSPFVDRHPENLLPSVLIVIFTILYALLVTKSRCVDRHEKKKAGYIFLQEDA
P-ASR

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2056)

QLYAVVVDTGFRSPARCSAKVYI---VLCGENGFSEPRELYCPEK-PLFE-----
-RNSRHTFVLSAPALLGRLRRIRLWHDSRGPSPAWYVSHVVVGELAPRHGRSWLFPAECW
LAASRRDGRVERELGCLRRGLGFWKLLYSKFTEYLEDFHIWTSMYSQPSPSGFPHTARLT
VAFALLCTYACLAALLTAAGQEQLPWALGDPDAA-TGSFRTGLLCTLLASPGAQLLSLLL
RLSQVPAAC-PH------------------------------------------------
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-------------------

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-----------------------GTMVHSNYSVGVEVLARVP

PF02010 // ENSGT00700000104221_7_Domain_3 (823, 994)

VAVISEGTHLFVPRA---
AREPVVLRGTQSFDP-----DHPGAVLSYHWTCTAARSPGRPCFDDTGPNQPDTRASIFS
FAVERLSTCCDQFLLTLTVASRGQYSSEAQVFLSTRQDPGFRFL--HISWLSFKDVYVNW
NEELSLRAVCDDCGETLSLSYSWELFWVNATEK

ENSGT00700000104221_7_Linker_3_4 (994, 1218)

SSIEVPLCSTVQLLGVAAL-RAFWESP
ESALSAMEP----------SEELPV-GTPTPLPWGTPPEAL--------H-----HTVLG
SSASGRWIPAASDTTAPG-----EA-VEDQPRGPEPVAQAEGAPPTMSP-----SSRSQP
QPSSPPALDDFEDYYGNIQEAE-PAGGRQPGHSTGV------SSADA---AEGSP--GEG
DNLLDPFTSADRASPVL

PF02010 // ENSGT00700000104221_7_Domain_4 (1218, 1389)

TIDWPKARLSRAVLRGYTEA-GITKPTVTLKPYSLSSGETYVL
QASVASAAEPSELGRAQLYVRVPRVPRDAACQVQPQRGL--EALTIFSVFCMSGTPDFHY
EFSYWVGNAS-RHTLYRGRDTQYYFALPAGDPLDNYKVMVSTEITDGQGSRIQPCSVAVT
VLPRYYGNSD---SC-ASSRYNSSLRNLSVLWLMGSDTESRNYIAMLTG-ILSRLAKENT
ST-SCDQWSPLQDALISAVCTLAFADEEEMMDSVHTLRNLVNLPIKLGFLSAARILRFAH
TLLVQDQT-HFSGKFVGAGGRRLELILLI-SGVWEASEHGTWRH-EDYILEEGKRVISDM
LL----------LSVSAGQMEFRVLLHRGLHCSVQSLGSVLVHLPRDLA-GLSPAAEETQ
APCYISQLTLFRRRLHPGGGAAG-QVGGI-LGLSLYSCPSRSPIRRRQLRTPVTVEFGD-
-EDS-GVRMPSSSFVLLREQVHFHQFA-LLSQHPQELLQIHIEFAELETPAFPVLLLFS-
FSKKPSPSDFLVQQTRFQDQQSVRIFAPTALGRA-------ANVGYLSLLDAYYDRRAPS
TFLAKAVSYTAHFQWIRCLFWE-RGEWKSGRFSPQPGTSPDKVNCSYDRLA-PFSTLRRR
LNASFEASDISEVQSPPQNLLPSVCMGVITVLYGLLVMKSNLVDRRKEKGPGYIFLQEAA
P-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2045)

YAVVVDTGFWSPARFTSRVFI---VLFGESGLSETRELCCPER-TLFE-----
-RNSRHTFILSAPAQLGPLWKVRVWHDSSGPAPRWLLSCVMVKELQSG--RAWFFPARCW
LAAGQGDGRVERELPCLRQGLGFWKLFCAKLTEALEGCHVWLSLCGPPRSHGPSRTQRLA
VSLCLLCTHACLTALATAGGRDQLLPDV------VLGDLGLGLLCALAASPVAQLLPLLF
RCSQVPARG-SQARRTP-GSWSLRSALLGVPHAPQPT--------LCWPWPPSRGP---L
PHPG---------SPS---------------------------------LLSWG------
-----------TGSHCPSP--SDGHEGL-EPQGPSACQLPPNTAAWTICGMVTLACGLGT
GFLGYRFLPAQCAQWLLLLSLSVVCCAFITQPLLICC-AALGFAWKRRADSQ--------
---CFAESLREATEHL-GSGLEERPGPHT----R-AS----PGPTAGLAEVLAARQRERH
LRR--ARPPSRAQLRVTRERTKRARRAQAALR--GLAMHGLTLLLLTWLTHGAFSTAAEH
ALNRAIR-------------------------------------------KALPGALGGK
CYLLGASVIQQPQD-------PPRPSPAPLEDSLPLWSPDP-RGLED--------QNLTH
-GGP------------------GHCLLSPGRTRL--EAQALLSTLRARGWAAA-----SM
RLVLYHPPSQLFTSIALRAQPLPAA------WVESFRVFWVAQARLKHVVLLSLSEIPCP
LQLAFLVLSLARLSLHLYSMAEVGALSYWRRPRNWLELPALGAALAYYAACGLLSLHAGD
VAQQLRGGPCQGPLDLSLMALWSQRARWLRGLLLFLWTLRCISLPGLLHTWKLTPPFLST
WGRSSGSWLFSLLQLVGALVLAAHTHL-RHL-LSAAWTLPP-RTFAHSGSRLLLLLGLPG
RSQEDSSPSL---PTSHLI---CLF-----------HSLLQLRVSLLTCFHK-SKSSRGN
PPVRLTDVAALSWQEALAFLGLETPAAGEMEAAVDHVCLGLDTEFSSLLDELLVKVEALS
HGLELPALEEPRP-----------ADDSPAVSIP-AHRAPG-------------------
-------------------

---MA---EEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVN-
-------EKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFYHRQLCATGTADSIFSGL
LQ-LQGTTSAAAPCSLKMEASCYVLRLLCCAEDVATGL----LPGTVTMETPTKVARPTQ
TSS----QRVPLWPIS-----HFPTSPKSSHGLP--PGIPRTPSFTASQSGSEILYPPTQ
HPPVAILARNSDNSMNPVLDCSLEMEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMVVTAYHQYSKGN---FFHLLHFQLDMSTYKEAETQ-----NTTLNVYLCQSE
NS---CLE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEVELGPYYVEIGHEA
VSAFMNSSSVHEDEVLVFADSQVHQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYKMQSVSV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDIIFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVTVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHIIRVQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECWINFGT
DVAYLWDFGDGTISLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRQQLFIVCKPCQPPL
VKNMGPGKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISQGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSRIVLRGTQSFDPD-----NPGATLRYHWECATAGSPAHPCFDSSTGHQVDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSAFRFV--HISWVSFKDTFVNW
NDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISESS
QLNLLPTEP----------GTADPD-ATTTPFSQEPSPVTLGQPAPSAPR-----GTPTE
PMTGVYWIPPAGDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPDPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPGSGPSLSA--E-ESP--GDG
DNLLDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSS-GITEQTVTIKPYSLSSGETYVL
QVSVASK--HGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLGFMSAVLILKYTR
ALLAQG---QFSGPFVVDKGVRLELIGLI-SRVWEVSEQENSKE-EVYLHEEGITVISDL
LLGCLSLN-----HVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGSQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGLDNRRNKTTFVLLRDEVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPK
RYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYHRLA-AFALLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEAS
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG--QAWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQPQLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGS-ARVEPHS-PLRG--GAQTEAPHGPNS---------WGR-IPDTQEP---C
KQPASAILSGSGRAQRKAAS--------------DSG---TACPA-PK-LQVHGADHSRT
SLMGKS---HCCPPHTQAP--SSGLEGL-MSQWSRALQPWWSSAVWAICGTASLACSLGT
GFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCL-MALGFAWKRRADNQ--------
---FFTESLCEATRDL-DSELAERSWTRL----PFSSSCSTPDCAGEVEKVLAARQQARH
LRW--AHPPSKAQLRGTRQRMRRESRTRAALR--DISMDILMLLLLLCVIYGRFSQD-EY
SLNQAIQKEFTRNARNSLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGK
CYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEV-GGPEDPYLIDPENQNMTL
-NGP------GGCG----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2903)

VLSLGRTRT--EAHTALSRLRASMWIDRSTRAVSV
HFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------MLP
Q-LVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGD
VTDQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS---M
MRHSLP--SIFVAGLVGALMLAALSHL-YRFLL-SMWVLPP-GTFTDAFPG--LLFHFPR
RSQKDCLLGF---SKSDQRDMACYF--GILLIVSATLCFGMLRGFLMTLPQKR-KSFQSK
SFVRLKDITAYMWENVLTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKTSN-----NTGEARTEESPLVDIS-SYQAAEVRPCKIIYVNFLHSNLSSK
GVLE---------------

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------YQVMVKASNKISSITSDPHSICVQRKIVP

PF00801 // ENSGT00700000104221_7_Domain_1 (636, 704)

NRLVSGSSVLINSSLSFECRINFGT
NVTHLWNFGDGSIRPGKSTESHVYTREGEYTVEVLVVNKVSSA

ENSGT00700000104221_7_Linker_1_2 (704, 749)

SLRKQIFVVREPCQPPL
LQSMGPGRIQIRRHETVTLQVTFAAPIM

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1384)

CNISRGLRYRWILIKSNGFLMPLPPTTDTHKQ
TVLLPRYFLDYGNYSAIAKVQIGGSMVYSNYTVQMEVLPSDLVSTISEGTHLFVPRT---
ASLIITLNGSESYDP-----DNPGARLQYHWKCAPASRQQQVCFNSSGDPPFNSRAPVIS
FPATLLDNTYDQFLVTLTVSSGHRTSSEAQLFLSVSSGPTLRSV--HISWVSFKGNSGNW
NEELSFKVTCEDCGQILDASYNWNLYLINATEPNDSEGPFCSTVDFLGTSVF-LSQFLTV
PQETSVMLASKTDVDSPGKQMIQPI-PTSMTFSQQISEKSPGSVTTSASS-----DSMSR
PATEVHLVLAADVPTENSSFSDADDLMQFMLPYSEPELFEEEFLD----------LRASQ
NERSSGSLSDFDLYYGNIKEAVEPPRGRQPGYTNSIS---GPVINEE---TNSFSTEEEG
YNLIDSFYSTDSAGSSLMVDWSKSPIDTDVFQSFTSS-GITSQRVTIKPFVLRGGEMYMI
EASVASN--HNLLGKAQLYFAVNEIPQGMTCQVQPSNGS--EADTVFSVFCTSGQADFHY
EFSYSIGNSS-RMPLYRGRDIQYYFTLPAGEPLDDYRVTIYTEVTNGRGSKSQPCAVDVT
VLP

ENSGT00700000104221_7_Linker_2_5 (1384, 1816)

RFHGQYSLS----PLLGYSSGLKNLSTLLLMGSYTEIRNYVTVLTR-VLNRLYAEDR
DT-DPDKPSQIRSALISSVCNLPFQEQEELTDSVLMLTDLISTATEVTFSSAVQIIKYVK
QFTNHN---TFSGIFVLDKELTTKLVFLA-SGVLKISEQEESAH-AEYLMSEGSKVITDV
TLTCYKLS-----YISTGQLELQTTLHSTFQRTKLTVGSTKFHLPDALD-QQVIPRSGLF
QQCFISQIIYFRKNPYFWRTAPVQIAGDA-ADLSLYSCASRRKINIQRLVNPVTVEFER-
-KDT-ENNEKRTIFSLSRDKMNFHQFR-WLPKSSQESLQITVEFSKPTSRTFPVLLLVR-
FLEKPTPLLFNVKQTHFWDHQVVQIFIPAVALKS-------PGSGYLSLLDADYNRKPQN
KYFASIANYAFSVRG

PF01825 // ENSGT00700000104221_7_Domain_5 (1816, 1857)

IQCLLWDIEREWKSGGCHPQQGTILGNINCSCNHLT-TFTV

ENSGT00700000104221_7_Linker_5_6 (1857, 1928)

VSRE
LNTTLETAGVFQDRSTGKNIFPCMFLSSFGILYVVLAIVSKFTDAHEAKKKGYIFLQDNM
S-TDRQQ

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2044)

YAIIVDTGFRSQAQLSAKVHI---VLYGEDGLSETRELSCPEK-PLFE-----
-NNSRHTFILSIPESLGPLWKIHLWHNNSGPSPSWYVSRVTVKDLMTG--AHWVFPAECW
LAV

ENSGT00700000104221_7_Linker_6_7 (2044, 2538)

DKGDGRVERELTCLRRGSVFRKLLYSKFTEYLEEFHIWFSVYSHPSYSSFTQTQRLT
VCFVLALGYMCFDALLTHLEPEELSPDLGLTEI-SALTMMKGTLSTLIIFPMALLLSFLF
RFSERRISD-HGLGGD----------QLSSP--RNPN--------NHGGVLNSLTP----
-----GVPSGTISGRAERESDLT-------SGRSSSGFEACHCDHQPIRKRGHG----HH
PLYSSE---SRSTFRPPVP--RRQME---------QPTTLWRYVAWAICGLVSLTCVVIT
GLLGFGNGSISKSNSIHRCVTSTESCLLITGQANVV---HNLREWENLCHPH--------
---FGLKELSKVGRRV-NMGLSQLLFTTLATKNNFYIPSKGWGPPGQIHSILAIRQRSRH
SRW--ARPPTPAQLKEAKERIRKETVIRETLK--EFFLHTLMLFLLLFMILGNISKE-EY
FLNQAVRNEFTRNTQYT

PF08016 // ENSGT00700000104221_7_Domain_7 (2538, 2979)

FGDLKDADGWWNWSLTTLLDSLYKDKWQNTSGPRTESGPNGDN
CYLIGPAVLQQLKLPGDYACEVSGRFSDDFKDQILGYHPRV-QASNRTRALDNEKQKMCR
-TGRSRLCGQVDCY----EG--SSSAVSLGRTRT--EAYSILVNLKRRRWLDMTVGAVGV
QFVLYNPPTNLFTSVFLLVEFPSTGGLVPSLRIESVDIYHINSVSSYCV--------RVS
E-LLFLGLILLHLCSQFWIMNQMSILSYCQEPWNWLEFSIIGLSFFLYAIHMHHFVLAVD
VIDQLHKGFFQGFVDFSFIASWGQKTRCLQGILSFFLLIKCIRLLGVHKPMASCST---M
LWLSCS--RITKTVLAAVLLTMAYSYL-GRFLL-LSNALAF-DSLIGSIRT--LPLDFLE
ILERETVLLF---YKSNCYVTVCYY--GTFLIVMFFLWDLMMRGVLASFARDAKKSLRNR
QLVRFEEIIAYIQKKMSSLLGLQRQTPDHSGPLEDHTF-YLD-EVEHLMDELLFRITALS
NGLSVSLPEQS-------------------------------------------------
-------------------

------------------------------------------------------------
--ELHAEPLLWRSRGKHGCRSCSLRGTAGSVGSQEPSPPASWEKSVYQSSQQAMLKARGP
AASGVADGAAQAPRDWGGSTDGGPRPPSVPIGSLWSGHSPRSPRRQLCAAGNAGGSLSGL
LKGT---SRGVAPCNWTVATSCRILGGQCSAGDAAEGLEGLPRPGTEAAGSASAPP----
----------------GPPFPLP----TSPSSLCLPPAASHSPSLSVSWSGPRMLCVLTQ
CPPGTVPMRGTDGALDPGLHHFLETDAQAPPVLGLRVHTASGAALCLLMAFGDSAGIETS
LYNVTKAATVTACHQEGKAHACNVAHSF-------SYTEVHGAASSPKTSRGWPRPRSQS
Q---TPRDDGDGRVGNPDMCLL----STQAVHSLRALIDDGVRGGPVELGPYFVEVGREA
VSVFMNSSSVHAGEALAFAGSHANGKGVVVMHRFPSVSSYTVSFASRTQAGLGPAWRSVA
VCYRMQPLSVYTNGTVFAADADIAFEAVTTETIPLEFVWYFGNDPPVQTTSRSVR---RR
LRVPRGYQVTVKASSMVSSVVSKPHLVRVQQRIVANRLLSAAS

PF00801 // ENSGT00700000104221_7_Domain_1 (644, 704)

ALVNTSVAFECRISFGT
DVAYHWDFGDGTVSLGSHRSSHVYSREGEFTVQVLAFNAVSTA

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLQKRLFIVREPCQPPP
VKNMGPGKVQIWRSQPLRLGVTFEAAVL

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1384)

CDISQGLAYTWSFLDAKGSHVPLPAAVNTRRQ
TVVLPGYTLASGNYTATAKVQIRGSVVHSDYCVGVEVRPRAPVSVIAEGTHLFVPRN---
APAPIVLRGSQSYDP-----DHPGATLRYYWTCSAASSPGQPCFEDSLPSLMDTGSPTIA
FSARWLSTCCDQFLMTLTVSSGGRNSSEAQVFLSTRQDPTFRFV--RISWASFRDASVNW
NAELSLRAACEGCGDVPGLSFSWELFLVNATEDGTVAAPSCRAVGLLGVSGL-GAVWKSS
EPIPLSTEP----------STPDPE-GAPMLFPREPSPETLGQPAVSAPG-----SASPE
STAGPRRAPAAGDTVVPG-----ED-PEEGLLGPELASWDEEAPTGSP-SES--------
-GWSPPHPVDFEAYYSDIQEAE-PSRGRQPGG--NTS-PPESGASED---DEGSP--SEG
DNLVGPFLSAGRAQPALLIDWPKTPVSRAVFQSYTSS-GITGPVVTIKPFSLSSGRTYVL
QASVVST--HGLLGKAQLYLVMNRAPQDVACQVQPHQGL--EAHTLFSVFCMSGKRDLEY
EFSYQIGNAP-RRTLYHGRDAQYYFVLPAGEPSDGYKVTVSTEITDGLGSKAQPCAVAVT
VLPRYRG-----MHCPTEDLYNSSLRNLSTLQLMGSYTEIRNYVTMLTG-ILNRLTTEDG
SA-SCGQWPLIRDALISSVCSFAFADEEEVMGVVPALKDLVSFPPKVSSASTLLLLRFAR
VLLTQG---RLRGGLVLGLGLRLELIRML-SRVWEGSGQEEALA-RTPVWEDSLEVVSAL
LLGCLSLHHERELRVSAGPVEFLALLHSGPQQSVQSLGPVQVHLPGDLA-GHSRAGEETQ
SPCYISQLVLFRKNPHPRAGRAAGQVGRA-VGLTLHTCSGTRPIRRHRLASPMTVEFGE-
-DDGPGSRRSKTAFALLRDRVNLHPFA-GLSEDAQESLQIHIEFSTPASRAFPVLLLVRW
FSERPTPSSFLVKQTFLWEGQTVQIYTPAAAWKA-------SRVGYLSLLDADYNRRSPN
KYLAELVNYTVRFQWLRCLMWD-KGEWKSGSFSPQPGTSPEKVSCSYDRLA-LFSVLRRE
LNTSLEVSHVSELRSRPRNLIPSACVVVFTVLYGLLAAKSRGVDHREKEKTGSIFLQEEV
P-PGHQLYAVVVDTGFRAPARFSSKVQWYIVPVWRERDFSETRELHLPAGGPCFEKEF

PF01477 // ENSGT00700000104221_7_Domain_6 (1979, 2044)

QT
HPFSRHTFVLSAPAQLGALRMICLWHDGRGPSPSWFVSHVMVKELRSG--RAWFFPAQCW
LAA

ENSGT00700000104221_7_Linker_6_7 (2044, 2662)

SRRGGRVDRELACLRRGPGFWKLFHAKSTEYLEDFHVWLSVYSRPSGSGFLHTPRLA
VSFCLLCVYACLAALVTTGAHSQLFPAAGPTDL-TLRTSGLGLLCSLLGSPAAQLLSLLF
RLSEEATRP-PQAGPGS-PQRGVQA---RAPQDSGPN--------SCRKTLDAPEP---D
QHPASAALSGHHQ-----AWRKAA----------SSQS--TACPHQG--SGTWGASRSEP
VLGEKS---HCCPARPPAP--GRGPGEL-LLPRPRALLLWSGRAAWAVCGTTSLACALGT
AFLGYRFEPAQCMWWLHLLLLSVVCCVFITQPLMICV-VALGFAWKRRDDSH--------
---FFAESLNEATRDL-DVGLEGRSRTHG--------CPCGPGCVGAVAEVRRPCLQAEQ
LRL--ARGTCHTQLKVTRGRMKRERRTRAALR--DVSVHALRLLLLLCLTSGRFSPE-ES
SLNQALRKQFTSSAAHSWDGPRSPEGWWDWSLTVLLDGLHPAG----PSPGAQPGPLGGR
CHLLGSPVIKQLKVAPQGSCKPPGPSSATVEDSPRSQSPEA-EG--------PENRNRSP
-SCP------GGCG----VS-

PF08016 // ENSGT00700000104221_7_Domain_7 (2662, 2801)

-ADCVHSLGRTRR--EVQAALTGLRASRWIGRSTRAVSV
HFTLFHPPSRLFTSVALGVEILPTGALVPSSQVDSVSVFRSDSALDHGL--------VLS
E-LASLVLSLAHLCFQVYAMVDEDGLSYWHKPGNWLELAVAGTGFTYHVAAGHLATLAGE
VADQFHRGFYQVFVDLSPMVSWNQ------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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-------------------

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----------------------------------------------LSFDSAVLILKYSR
TLLAPG---QLSG-CVVDKGLRLELILLI-ARVWEASEQEKSRE-EDYLREEGIEIISNL
LLSCLSSHPERRLYVRTGRMEFWTLLHQNFQSSVQNLSSIQVHLPGDLT-GHSPEEVKTQ
SPCYISRLILFKKNPYPGRQDAG-QIGGV-VRLTIFSCSSRRPINRQRLKKRVTVESGE-
-EDDRDNSKNKTTFSLLREKVNFHQFI-GLSENSQESLQIRIKFSKPNVKAFPIMLLVR-
FFKKPTPSDFLVKQIYSWDEQTVYISVPAVSWKD-------ADVGYLSLLDADYDRTPPN
KHLAETVNYTVHFQWTRCLFWEQ-REWKSGSFPPQPGSSPGRVSCSYDRLT-AFSVLRRG
LNASVEVSDIATLRRHPQNLFPSVFVMVSVIVYGLLVIKCRHADRHEEKKTGYIFLHGDA
L-PDR

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2056)

QLYAVVVDTGFRTPARLTSKVYL---VLYGENGLSETKELYCPDK-PLFE-----
-RNSRHTFILSTPEQLGPLRKIRLWHDSRGPSPEWFVSHVMVKELHTG--QPWFFPAQCW
LAASRGDGRVMREIT

ENSGT00700000104221_7_Linker_6_7 (2056, 2669)

CLHQGLGFWKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXXXX--XXXX--XXXXXXXXXXXXX--------XX--XXXXXXX---X
XXXXXXXXXXXXXXXXXXXX--------------XXX---XXXXX-XX-XXXXXXXXXXX
XXXXXX---XXXXXXXXXX--XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXFGPAQCEQWLCLLSLSLVCCVFVTQPLMICI-VALGFAWKRRDDHH--------
---FFTESLGEATRNL-DSELEGLARMPF----ALSPHRCLPECAGQARQVLAAQIRARH
LRL--VHPPSTNELKDTRVRLRTSHPTQAALK--DISLHILTLLLFSFIIYGTYPRE-EY
SLNQAIRKEFTRGR--TLGAVRSVEEWWDWSLTTLLDGLYPGGTLAAQEPRAQAGALGGK
CYQIGSLLIEQLKVSPSSECKPPRMSSGLTGDALPACSSKV-GDFEHSYEIFPENQNVTL
-CRP------EGCG----VR--ANCVRS

PF08016 // ENSGT00700000104221_7_Domain_7 (2669, 2768)

LGRTRR--EAHAALSSLRTRRWINHSTRAVSV
HFTLYNPPTRLFTRLTLSVEILPMGSLVPSSLVESFSIFHSNTPLRYYL--------ILS
Q-LAFLVLNLAHLWFQLYNLIEKGGLNYWRKPRNWLELSVAGVGLTYHAACGHLATLAGG
IADQFRQGLCQASLDLSLVATWNQRVQWLQGILTFLLALKCIYPLGLQKTMVSCSS---T
RHRLPT--SIIAPGXXXXXXXXXXXXX-XXXXX-XXXXXXX-XXXXXXXXX--XXXXXXX
XXXXXXXXXX---XXXXXXXXXXXX--XXXXXXXXXXXXXXLRGSLMTFSGKR-KPFQSK
HLLRLRDVAVYAWGKALTYLGLEKPMLKEPETAENQNY-YLD-EFVNLLDELLMKINGLS
DSLQLPLLEEPIR-----STMKEKEEGSSQATV---------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------FSNPP--PGISHTCNLSASWYHPESSSPLTQ
HPPRATLVIQPENAEHFAICCFPETDAQAPPALGIRVHVASRTALCLLLDFGDSCGAQMR
LCTLTGAATVTGYHQYRKGGV---------------------------------------
-------------------------------YKLKA-VVHDFHKV-KELGPYYVDIGHGN
VSVFMNSSSIHDSEALSFADSLPQQRGTVVVHCFSSISSYNVSFISQTQVASRQAWCGVT
VGYKMQSVSVYTNGTVFAADTNITFVAITEETIPLEFAWYFGENPPVMTTSRSIR---RR
LSVPQWYRVKVKATSRIGSVVSEPHLIRVQKRIMANRLVSTAS

PF00801 // ENSGT00700000104221_7_Domain_1 (644, 704)

ALVNANVSFECRLNFGT
DVAYLWNFGDDTIELGSSSSSHVYSREGEFTVEVLAFNNVSSA

ENSGT00700000104221_7_Linker_1_3 (704, 749)

TLRKQLFIVREPCQPPP
VKNMGPAKVQIWRSQPLRLGVTFEAAIL

PF02010 // ENSGT00700000104221_7_Domain_3 (749, 987)

CNISQGLSYTWSFVSAEMTTVTLPAAVNTRRQ
TIMLPSYTLECGNYTAIAKVQIKGSMVYSNYCVGVEVRARAPVSVISEGTHIFISTA---
TSTFIILRGAQSYDP-----DNPGAALRYHWTCTAASSPKWPCFDNSTSYQVDTQAPAIS
FPAKWLSECCDQFLVTLTVSSRGQNSSQALMFLSTRPDLAFRFV--HISWVNFRDISVNW
NEEVSLRAVCEDCGDVPDLTYSWDLF

ENSGT00700000104221_7_Linker_3_4 (987, 1218)

LVNATEKSAVEVPFCSTVGLLGALAL-GASLKSS
KSDLPSN----------------LR-APLAPHSPEPSPTPLGWTALSNLG-----SISAE
STAGGHHVPAPGAVAGSG-----EPMEEYSSLS----SLAEEALMTNSS------EGSWP
SPSSSTDFDDFEAYYSDIQEAV-LSLGRQPGT--STN-FQEAGPSLSA--E-ESA--SYG
DNLLGPFLHTGRAKPTL

PF02010 // ENSGT00700000104221_7_Domain_4 (1218, 1405)

MIEWPKALVSQAAFHGYTTS-GIMGPAVTIKPFSLSSGKTYVL
QASVASK--HVLLGKAQLYLTVNQAPQDMSCQVRPHHGM--EAYTIFSVFCMSGKPDFHY
EFRYRIGNTS-SHTLYRGQDTQHYFLLPAGDSSDNYKVIVSTEITDGHGSKVQPCTVAVT
VLPRYHG-----NDCCDKDLYNSTLESLSTLWLAGSYMEIRNYITMITG-ILSRLYVESR
NTSSCGQWSQIQDVLISSACKVPYTDQEGMMDSIHILRDLISFPNKLSLTSAMCIFKFTK
MFLAEG---QFSRRLLVDKKLRVEFVLLI-SGVWEAAKED-SRD-GDYLQEEGMKIISDM
LL----------IHVSTGQMEFQTLFHRSPQSSIQNLGFVQIHFPSDLASLHSTTQEATQ
SSCYISQLMFFMKSPYLGGQVPG-QVGGV-MIPRLYSCKSRRPILRGQLETPVTMEFGE-
-EDYL-HKRNPAMFVLLRDEVNVHRFT-GLSENSQESLQIHIKFSKPVTRPFPIILLVR-
FSEKATPSDFLVKRVYFWDEQTVQMYVPAAPWKG-------ANVGYLSLLDADYDRKPPN
KYLAGAVNYTVHFQWIQCVFWDK-TEWRSEGPYPQPGSSPEKVNCSYHHLA-PVSVLRRK
LNATLEVSSISEFQSHPHNLLPGIFSAFLLVLYGILVSKSRYVDCHEKKNPGFIFLEEDT
L-PGYQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRSPVRFTSKVFI---VLCGENGCSETKELCCPEK-PLFG-----
-RNSRHTFILSIPNQLGPLQKIRLWHDSSGPSPCWFISHVMVKELCSG--QAWFFSAQCW
LAVSKL

ENSGT00700000104221_7_Linker_6_7 (2047, 2665)

GGHVLREFFCLSHGLGFWKLFYSKFTEYLEDFHIWLSLYSQPPSTSYLHTQQLA
VSFCLLCVYSCLTALVTVRDHQQRPLDVGPTAI-TLEPFCMALLCTLLACPVAQLLSLLF
RCSKEARGD-MQASTQ--WPLR--GVKTETPQGHDSS--------GR---PDSRQP---S
PHPTSDLLPWTDQAWRIAAS--------------SSA---VVCSP-FP-MEACSHKHH--
DLREKS---HYSPPSSQAP--GSGFEEL-GSQKSRVCLLWSSSVAWAISGSASLACGLGT
GFLGYWFVPAQCMWWLYLLLLSLVCCAFITQPLMICL-AALVFAWKRKHDSK--------
---FFTESLQDATKGL-DLELEEHSRTRV----PLSPISYSPDTAEEAERVLATRQRERH
LRW--AQTPSRAKLRVTRERLRRESIMQAALR--DMTTHSIMLLLLLFIAYGRFCPG-EI
SLNHAIGKAFTRKANHSLGDLSSTEDWWDWTLSTLLDELYPERTSA-RAWGAQPGALGGQ
CHLIGPPVVKQLKISAGTACTPPRPFSELVEDVLPMHSNDL--D--------LENQNVSP
-GGP------ETCG----VKK-ES

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2880)

YMHSLGRTRH--EAHAALTALRASKWIDHSTRAMSV
HFTLYNPPTRLFTSVILGTECLPSGGLVPSFLVESFRIFYSDSALKYLL--------MLS
E-LLFLVLNMIHLCFQIWGMTTKGILSYWRKPRHWLELSMVGVALAYYAASGNLTTLAAN
ITDQFHKGLYQRLVDIDLMVSWHQRVRCLQGILLFLWMLKYVHLLSSLSTMTPFSA---V
TCFP-----LFRVLLVGALLLAAHYHS-RWFLL-FTGTLSR-GTSAEAFPG--LLLQFPG
RSKKESWHNC---LKSDHEAVHCYY--GTLFLLLATLGFRMLRATFLAVFQNR-KSSHRK
SLVTLKDIAVYTWHKVLTLLGLETT-LEETEVATDHIY-YLD-EFSSLLDELLMKIDGLS
DSLELSILENQWR-----RALESRAGDSPPVGSS-EYQATGVSGPLAAE---------SE
-------------------

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-----------------------GSVVHSNYSL

PF02010 // ENSGT00700000104221_7_Domain_2 (814, 1407)

GVEVRARAPVAVISEGTHLFVPRA---
AGAPVTLRGTQSYDP-----DHPGAALSYHWTCAAARAPGRPCFDGAAPRQPDPRSPTWS
FAAERLSRCCDQFLVTLTVASGGRSSSEARVFLSTRDDPAFRLL--RIAWLGFEDISVSW
NQALSLRAVCEACGEAQGLSYSWELFRANATEDSGSQVPFCSTSQLLGTMAL-TATGKTP
ESDLPD-------------------VGTPTPSPQEAPPAALHWPVFGVPG-----STSMQ
PTVGGHGTPTAGDSAALG------KPLEGSPRGPEPATKSPS-------------VQSQP
PPSSSPALDGECT-YPFL-----LSGAR----------LPGSGPSAEADAAQGGP--GEG
DSLLGPFVSADGAPPVLTIDWPKAPVRREVFQGYTAA-GITKPTVTVQPYSLRSGETYVL
QASVESG----LQGRAQLYVSVRPAPQDTTCQLQPHRGR--EALTVFSIFCMSGTPDFHY
EFSYRIGNTS-RHTLYRGRDTQYYFALPAGDPLDNYKVVVSTEIADGQGSRVQPCSVEVT
VLPRYHG-----NSCPSEDL--SSLRNLSTLQLMGSDMEIRNYVAMLTW-ILSRLAKDNT
TT-ACDRWSLIQDKLISAVCTLAIADQDERIDSALTLRNLVSLPIKLRFPTAARILRFAR
ALLRD-QA-QLPGRFVGDGGLGLELILLV-CRVWEAAEPGKLGH-EDFVQEEGMKVISEA
LL----------LSVSTGQMEFRILLQHGPRSSVQSLGPVLVHLPGDLA-RLVPAGEETQ
SLCYISQLTLFRKSPYPWGQAAG-QVEDV-VDLALFSCPRRSPVGRRRLETPMTVEFGG-
-EHS------EGPFSLLRGRVNVHRFS-GLSPHPRESLQIHIEFAEPETRAFPVLLLLS-
FSRRPSPADFLVRQTHFWDTRSMQVYTPAAAGPG-------ASVGYLSLLDANYDRSPPG
ERFAEAVNYTVRFQRIRCLFWD-RGEWKLGSFPPRAGTSPDRVNCSYDRLA-PFAILRRT
LNASFEASDVSQLHGHPRNLLPSLCVVVFAILGALAVMHSRLVERHAEKRAGCIFPQGAT
P-PGHQP

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2043)

YAVVVDTSFWSPARFTSRVFI---VLCGENGLSETKELCCPER-TLFE-----
-RNSRHTFILSTPAWLGPLQHVRLWHDSSGPAPSWRLSRVAVKDLRSG--QAWLFPARCW
LA

ENSGT00700000104221_7_Linker_6_7 (2043, 2676)

AGRGDGRVERELPCLHHGLGFRKLFYAKFAESLESGHTWLSLCTPPGSHGPPRTQRLA
LCLCLLCVHACLTALATARGRGQLPLDVGPTDL-TLGALGLGLLCALAASLAAQLLSLLL
RHSKVLGPM-RGPAPRQ-RLHP--GHRLS-------------------------------
---------NQPAGPRP-----------------AKGG--TTCSL---------------
----TH---VCLSHCPTGP--SAGCEGLA-VPGSRAGPPRPSTAAWTACGLVSLACGLGT
GFLGYGFLPAQCARWLLLLSLSVVFCAFVTQPLLICC-SALGFAWRSRGDSQ--------
---CFAESLHEATGSLPGSGREECAGPHI----PAPPGSR----EPGVAGVLAARQRERH
LRR--AQPPSRAQLRATRERMRRERHAQAALRWVDIALHVLALLLLLWMTHGTFSAD-AH
SLSRAIRKEFVRKRKSSCPHATG--------------GVT---SAAPPALFSQPGALEGK
CYLLGAAVIKRPKASTSSLPKLPWLFPALLEDALPLWSSE--------------DQNVTR
-GGP------GGCG----VRR-DARGPSPGQTRSV

PF08016 // ENSGT00700000104221_7_Domain_7 (2676, 2862)

CEASAVLTALTASGWMDGSAGAVSV
HLALYNPATQLFASVTLSVDAPPNGQPLPSAWVESFRVFGGGSASWYHR--------ALP
E-LAFLVLSLVHLSLQLSEMAEGGTPRYWRKPRNWLELPAVGVAFAYYVANGLLAGLAGD
VADQVRQGPCRPSLDLRPMVSWGPRVRWLRGLLFFLWTLKCVSLPGLLGVAMPCCS----
-----RVWLFSLLQLVGALLLAAYVHL-RHLLC-AAWVLPP-HTSAHPDPR-LLPLGFPR
RSQGYLFPAL---STSRCGAKAEHLGALATVVAMLCLGVVGLRVSLLTCFQK-REPCHGK
SPVKLEVVATFAWRKMLAFLGLEEPELEEAEAPMDHSH-HLD-EFSSLLDELLLKINALS
DGLELPAVEGPRA-------TASRAGGSPEACIS-GYKAPR-------------------
-------------------

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---------------------------------MGNFGEIRNYITMLTS-ILNDFYTEDQ
SS-TLSLQSQMRNLLISSVCTLSFQDQEEMADSILMLNELISISKQVTFSSTVLIIKYVR
KLIDHS---NLSGQFVMNKELMSNVIFLV-SRALEVKEKEKSRN-AKYFRE-GIRNIVFL
LLNYVSSGKEFQFNISTGQMAFQTNLHYTFHNSVEHVGSVKVHLPDDLD-EYISKGMGLH
GQCYISQLIYFKEYPYLEEIVPV-QTGGVMVALSLYNCTSKRKISIKRLTSPVTVAFEK-
-SDAQDDEQNKTIFSLFRDKVNLHYFS-GLPETSQESLQIVVEFSKTILRTFPIMLLVR-
FSEKPTISTFNVKQIHSWDEQVVQIYIPAVSLKD-------AASGYLSLLDADYDQKPTN
KYLADIVNYTVSFHWI

PF01825 // ENSGT00700000104221_7_Domain_5 (1817, 1856)

RCLFWDEDREWKSDDSYPQQGTSPQTVNCSYNHFT-TFT

ENSGT00700000104221_7_Linker_5_6 (1856, 1927)

VVRRK
LKANFEINDVSLLRSIPQNLFPSILVLLSLLLFAFLAIASKRRDLHEQKKNGSIFLQGNS
QARDKQ

PF01477 // ENSGT00700000104221_7_Domain_6 (1927, 2044)

VYLVIIDTGFRAPAQLTAKVHI---VFYGEYEFSETRELYCPEK-PLFE-----
-RNSRHTFIVSIPNNLGPLWKIHLWHDNSGCSPRWYISHVIVKDLITG--ASWFFPAECW
LAV

ENSGT00700000104221_7_Linker_6_7 (2044, 2540)

NKWDGKVDRELTPLKSGLGFRKLLYSKFTEYLEDFHMWISVYSCPSYSCFTHTERLT
VCLFLVLGYMSLNAALIAMQQEEYFPEVGLLDV-SVVSLMNGMLSIFIISPVALLLSLLF
RLSEKKEEN-SAAFVRYSRHFGDYSIDLDIPKGS-HAHSKCPS--GHIHSSGQLKI---C
IHLPC----------RALKN--------------QIV---ICCND-FP-TQLS----QRK
MCLNQN---HLSENNSNSK--YDGLEEP-TPRKLMVLPPWLSYVAWATCGLISIACGLMA
GLLGYRFGPSKCIQWIHSVFFSIVGCIFVAQPLMIFF-VALALAWRKRDHKG--------
---FFIEALYDATKNL-EYELHHLSKNHA----LYSSYCSTPNTAADFEKILVARQRARY
LQW--VHPPTLAQLKEARWRIRKEMLLQTAIR--NFLTHILMLFLLIFIIFGKISHH-EY
YLNRAIQNEFTRNARNPFI

PF08016 // ENSGT00700000104221_7_Domain_7 (2540, 2976)

DIKNADDWWNWSLTTLLDGLYWDKENNDDIPRIQSGPLGGK
CHLIGPSIIRQIKFTEQ--------FSIPVEASSLSHQPQN-QDYENILQSESEKPKVIQ
TKRC------LSCGQVENEED-EVSVVNLGRIRA--KAYSILINLRNSGWIDKRTREIAT
HFVLYNPPTNLFTSVSLLAEVLPTGDIITSSLVESFSIYHFHSALSYCI--------LFS
E-LVFLVLSLIHLCFQIFIMIQKGILSYWQNSRNWLEMCIIGMSLSYFAHSIFHFILVVD
VIDQFHRGFFQVFVDFDPILSWHQRNRYLQGSLLFLLLIKCLHLLGIYKAIAPSLT---M
MRLSFS--NIILPLLAGVLFTVVYSYL-GRFLF-STHAFPF-RSFADSFQM--LLLCFLG
TNEKGTFFSL---YKSNQYTTVYYY--GTLFIAVIILWSGILKGVLIAFRQDAKRSCRSQ
PLVRFKEVADHIWEKVLSSLGIQRPLLAVAEIIEDSNF-YLD-EFENVLDELLLRVNSLY
YSLHCSPLEKSPR-----DQEEVDQKDKTLAYYL-SSPSVESNR----------------
-------------------

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----------------------PETDTQAPQSLGFRVQMASKGALCLVVDFGDSSGVRMR
TCNVSEEMAVTASHQYGKE-----------------------------------------
-----------------------------GVYMLRAVIYSEFYGTEVELGPYYVEVGHEA
MSVFMNSSSVHKDELLVFASSHMDQKSTVVRHCFPSFSSYNVSFTSRTHVGDNQAWPSIS
VWYQMQPVSVY

PF00801 // ENSGT00700000104221_7_Domain_0 (552, 621)

TNGTVFATDTDITFVAVTKETTPLEFVWYFGEDPPMRTTSRSVK---KR
LSLPQWYHVMVTASNGISSL

ENSGT00700000104221_7_Linker_0_1 (621, 643)

ASEPHCIRLQRRIVANRLTSTS

PF00801 // ENSGT00700000104221_7_Domain_1 (643, 704)

SALVNASVTFECRINFGT
DVAYLWNFGDGAVGLGNSSASHIYSSEGEFTVQVLAFNNVSSA

ENSGT00700000104221_7_Linker_1_2 (704, 749)

SLKKQLFIVRQPCQPPP
VKNMGPGKVQVWRSQPVKLGVTFEAAIL

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1394)

CDISQGLSYTWSFTNSAGLQVPLPPAVNTHEQ
TVTVPSYFLEPGNYTALAKVQVEGSAVHSNYCVGVEVRARAPVSVISEGTHLFVSRT---
PSTTIILRGFLSYDP-----DKPGAPLRYHWKCTAASAPGRLCFPSSSPHGLHASAPTLS
FAANSLSDTYDQFLVTLTVSSHGRNSSEAQVFLSTRPDSALRFV--HISWVNFRDIFVNW
NEELSLQAECEGCGAISTLSYSWELFLVNATEKHSVEVPFCRTVGLLGSSRF-GDISKLS
GSDL----------------LAAPY-VTTTPSSWKPWPKTPSRPALSALR-----RTSTE
SLVSMYRGSTAGGPAAPR------GTPQHE-GS--PRPSPSGRSSPPQS--PAP---HLP
GKAPSLRLANFEAYYSDIQEAM-PSKGRQPGT--NIN-LPGSGPNVN---ADESH--GDG
DNLLGPFLPTVSARPVLMVDWPKSLVRRAVFHGYTSS-GITEQTVTIKPYSLSPGETYVL
QASVASK--DSFLGKAQLYLTTNQAPRDVACQVQPHRGL--EAHTIFSVFCMSGRRDFRY
EFSYQIGNNA-KRTLYHGRDSQYYFALPAGEPLDDYKVMVSTEITDGEGSQVQPCTVAVT
VLPRFQG-----NHCPGEDVYNSSLKTLSTLQLMGSYTEIRNYVTMITR-VLSRWAKEDR
SP-SCGQWSRIQDALISSVCRLAFADQEEMNDSVLMLRDLIHFPNKLSFTSAVLIIKYAR
VLRARS---PLLGRFVVDKEQMLELILLV-SGVLEASDREKSRN-ADYPQDEGIKVISDL
LL----------LHISTGQMEILTLLHHEPQSSVQSLGPIQVHLPGDLA-GQSPAGPGMQ
SPCYVSQLMLFKKNPYPGGRAG--EMGRV-LHLSLYNCSSRRPFSRHRLRKPVTLEFGE-
-EGGPDNRRNSSTFVLLRDKVNFHQFA-GPSEDPQESLQIRIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDEQIVHIYVPAVSLKD-------TNLGYLSLLDADYDRKPLN
KYLAKSVNYAVHFQWIRCLFWD-TGEWKSESFSPQPGTSPEKVNCSYDRLA-AFSVTRRR
LNASFETSDISKLQGHPENLLPAIFIVVFTILYALLVTKSRRVDRHEKKKTGYIFLQENA
P-PDQQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2044)

YAVVVDTGFRAPAHFTAKVYI---VLCGENGLSEPKELYCPEK-PLFE-----
-RNSRHTFILSAPAPLGPLQKIRLWHDSRGHSPAWYVSHVMVKELCAGQGQSWLFPAECW
LAV

ENSGT00700000104221_7_Linker_6_7 (2044, 2666)

SRWDGRVERELACLCRGPGFWKLWYWKFMEYLEDFHVWTSVLSRPSGSGLLHTPRLT
VAFAVLCAYAGLTALLTTVGQEQLMLDVGPTEV-TLGSFWMGFLCTLLASPGAQLLSLFF
RLSQEARGP-PGEEPHL-PLRAVR--------TEAAQ--------GKLSSGGA-------
--DLSQPAPREESDPCTLSLQGDGT-------AGSKG---AVCTE-AD-PLQAG-SQEGS
HIPAHS---HPTTGKSRCP--GGGFEELTVPRWPRAPLPWSGSAAWVLCGMVSVACGLGT
GFLGYRFSPTQCLQWLRLLALSVVCCVFVTQPLMIGL-AALGFAWRRKDDKH--------
---FFTESLREATKGL-DSELEELSRTRM----PLSSGCSIPDSASEVEKVLAARQRARR
LRW--ACPPSPAQLRVTRERMRREMRTREELR--DICMYILMLLLHLFIIHGKFSGD-EY
SLNRAIQNEFTRSARSSSSSLRSVDEWWDWSLTTLLDGLYQESSFTAGTLGAQPGALGGK
FYLTGPSVIKQMKVPPGSLCELPSP-------------PSA-HIEGSLPTHNPTIQRVAL
-SGP------GGC------R--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2871)

VLSLGRTRP--AARAALTRLRASRWINCSTRAVSV
HFTLYNPPTQLFSSVSLNANMLPTGGLALSSLVESFHIFRSNSAR-YRL--------MLP
E-LLFLVLNLIHLCFQLYGMMEKGVRNYWRKPRNWLELSIVGAALTYSAASGHLGTLAGE
VTDQFHRGLFQEFTDLSHMAAWNQRARWLQGILSFLLILKCIYLPGIRNTMAPID-----
-GTHCH--GFFSLQLAGVLMLAAHTHL-RGFLL-SAWALPS-GAFSDSFHG--LLFHFPG
RSQRDTFLGL---SKSDRRDMACCY--GAFLIAVTTLWFGMLRGFLMTLGRK-RKSFQSK
SLVRLKDMTAYMVGKTLTLLGLERPKLDETEMVENHV-----------------------
------------------------------------------------------------
-------------------

----P---AENLAQSFKDVTVCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANRVLLMRDGKCDCPRCALKTKAEDRESQSPSSLPSGQKNIWKTTSKAALSVVNE
KTQAVVNEKTQAPLDCDHSADRIPHKPSIIIARVWSSGVRRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAAPCSLKMEASCCVLRLLCCAEDTAMGL----LPGTVTMETPTKVARPTT
T--------S-----------------SHSHSLP--PGTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQNSDNSMNSVLDCSLEMEARAPPNLGFRVHMASGAAVCLMTDLGDSSGVEMR
LHNMSEAVAVTAYHQYSKGKVIF-FLLLHFQLDISTYKEAETK-----NMTLKVYLCQSE
NS---CQE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTKVELGPYYVEIGREA
VSVFMNSSSVHEDEVLVFTDSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSVT
VWYRMQSISV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---QR
LSIPQWYRVMVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCEPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDIAHGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTVLAKVQIEGSVVYSNYCVDLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDP-----DNPGATLRYHWECATASSPARPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTKP----------GTADPD-ATTTPFSWEPSLVTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPVLMIDWRKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDSQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLAEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCHQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLSFMSAVLIFKYTR
ALLAQG---QSSGPFVVDKGVRLELIGLI-CRIWEVSEQGNSKE-EGYLHEEGITVISDL
LLGCLPLN-----HVSTGQMEFRTLFHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINWQWLRKPVMVEFGE-
-EDGLDNRRNKTAFVLLRDKVNLHQFT-ELSENPQESLRIEIEFSKPGTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------VNVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVTCSYDRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGFLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSTPAQLGLLRKICLWHDSRGPSPGWFISHVIVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFTLLCVYACLTALVTAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAEPHC-LPRG--EAQAEAPQGPNS---------CRR-IPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSGT
ALMGKS---HCCPPCTQAP--NSGLEGL-MPWWSRAPQPWWSSAVWAICGTTSLACSLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----RFSSSCSIPDCAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISMDILMLLLLLGIMYGRFSQD-EY
SLNQAIRKEFTRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPRPFSAPTEDSIPTCSPKG-GGPENPYLIDPENQNKTL
-NGP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2897)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLVPSSLVESFSIFRSDSALQYHI--------VLP
Q-LVFLALSLVHLCVQLYHMMNKGFLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCIYLPGIRNTMASCSS---M
TRHSLP--SIFVAVLAGALMLAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYL--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKTLTFLRLETPKLEEAEMVEYHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENISN-----STGEARAEESPLVDIS-SKQATEVRPCKIIYVNFLYSNLSSK
GVLEYLFFQIIRSICINIL

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--SPASHPPSFWRQILLKQSEDFTSQF---------------D----PPAPPFYSRVKAN
VLTLPMRP--TGGLSP-----PRLLVVLLHFCNLPPHLQEKMWEAISLSQHLFPVVPPSP
GENPCSDTGQSLALPDAPLSHSDDFSN

PF02010 // ENSGT00700000104221_7_Domain_2 (868, 1407)

RYHWECATASSPARPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTADPD-ATTTPFSWEPSLVTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPVLMIDWRKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDSQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLAEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCHQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLSFMSAVLIFKYTR
ALLAQG---QSSGPFVVDKGVRLELIGLI-CRIWEVSEQGNSKE-EGYLHEEGITVISDL
LLGCLPLN-----HVSTGQMEFRTLFHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINWQWLRKPVMVEFGE-
-EDGLDNRRNKTAFVLLRDKVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------VNVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVTCSYDRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGFLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSTPAQLGLLRKICLWHDSRGPSPGWFISHVIVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFTLLCVYACLTALVAAGGQEQVRLDVSP----TFGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAEPHC-PPRG--EAQAEAPQGPNS---------CRR-IPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSGT
ALMGKS---HCCPPCTQAP--NSGLEGL-MPWWSRAPQPWWSSAVWAICGTTSLACSLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----RFSSSCSIPDCAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISMDILMLLLLLGIMYGRFSQD-EY
SLNQAIRKEFTRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPRPFSAPTEDSIPTCSPKG-GGPENPYLIDPENQNMTL
-NGP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2897)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------VLP
Q-LVFLALSLVHLCVQLYHMMDKGFLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCIYLPGIRNTMASCSS---M
TRHSLP--SIFVAVLAGALMLAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYL--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKTLTFLRLETPKLEEAEMVEYHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENISN-----STGEARAEESPLVDIS-SKQATEVRPCKIIYVNFLYSNLSSK
GVLEYLFFQIIRSICINIL

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----------------------------XFSNPP--PGISHTCNLSASWYHPESSSPLTQ
HPPRATLVTQPENVEHFAICCFPETDAQALPALGIRVHVASGTALCLLLDFGDNCGAQMR
LCTLAGATTVTGYHQYRKEGV---------------------------------------
-------------------------------YELKA-VVHDFHRA-EELGPYYVDISHGN
VSVFMNSSSIHDSEALSFADSLPQQRGTVVVHCFSSISSYNVSFISQTQVASGQAWCGVT
VGYKMQSVSVYTNGTVFAANTNITFVAITEETIPLEFAWYFGENPPVMTTSRSIR---RR
LSVPQWYRVKVKATSRIGSVVSEPHLIRVQKRIMANRLVSTAS

PF00801 // ENSGT00700000104221_7_Domain_1 (644, 704)

ALVNANVSFECRLNFGT
DVAYLWNFGDDTIELGSSSSSHVYSREGEFTVEVLAFNNVSST

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVREPCQPPP
VKNMGPAKVQIWRSQPLRLGVTFEAAIL

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1406)

CNISQGLSYTWSFVSAEMTTVTLPTAVNTRRQ
TIMLPSYTLECGNYTAIAKVQIKGSMVYSNYCVGVEVRARAPVSVISEGTHIFISTA---
TSTFIILRGAQSYDP-----DNPGAALRYHWTCTAASSPRWPCFDNSTSYQVDTQAPAIS
FPAKWLSECCDQFLVTLTVSSRGQNSSQALMFLSTRPDLAFRFV--HISWVNFRDISVNW
NEEVSLRAVCEDCGDVPDLTYSWDLFLVNATEKSAVEVPFCSTVGLLGALAL-GTSLKSS
KSDLPSN----------------LR-APLTPHSPEPSPTPLGWTALSNLG-----SISAE
STAGGHHVPASGAVAGSG-----EPMEEYSSLS----SLAEEALMTNSS------EGSWP
SPSSSTDFDDFEAYYSDIQEAV-LSLGRQPGT--STN-FQEAGPSLSA--E-ESA--SYG
DNLLGPFLHTGRAKPTLMIDWPKALVSQAAFHGYTTS-GIMGPAVTIKPFSLSSGKTYVL
QASVASK--HVLLGKAQLYLTVNQAPQDMSCQVRPHHGM--EAYTIFSVFCMSGKPDFHY
EFRYRIGNTS-SHTLYRGQDTQHYFLLPAGDSSDNYKVIVSTEITDGHGSKVQPCTVAVT
VLPRYHG-----NDCCDKELYNSTLESLSTLRLAGSYMETRNYITMITG-ILSRLYVESR
NTSSCGQWSQIQDVLISSACKVPYTDQEGMMDSIHILRDLISFPNKLSLTSAMCIFKYTK
MFLAQG---QFSRRLLVDKKLRVEFVLLI-SGVWEAAKED-ARD-GDYLQEEGMKIISDM
LL----------IHVSTGQMEFQTLLHRSPQSSIQNLGFVQVHFPSDLASLHSTTQEATQ
SSCYISQLMFFMKSPYLGGQVPG-QVGGV-MIPRLYSCESRRPILRGQLETPVTMEFGE-
-EDYL-HKRNPAMFVLLRDEVNVHRFT-GLSENSQESLQIHIKFSKPVTRPFPIILLVR-
FSEKATPSDFLVKRVYFWDEQTVQMYVPAAPWKG-------ANVGYLSLLDADYDRKPPN
KYLAGAVNYTVHFQWIQCVFWDK-TEWRSEGPYPQPGSSPEKVNCSYHHLA-PVSVLRRK
LNATLEVSSISEFQSHPHNLLPGIFSAFLLVLYGILVSKSRYVDCHEKKNPGFIFLEEDT
L-PGYQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRSPVRFTSKVFI---VLCGENGCSETKELCCPEK-PLFG-----
-RNSRHTFILSIPNQLGPLQKIRLWHDSSGSSPCWFISHVMVKELCSG--QAWFFSAQCW
LAVSKL

ENSGT00700000104221_7_Linker_6_7 (2047, 2665)

GGHVLREFFCLSHGLGFWKLFYSKFTEYLEDFHIWLSLYSQPPSRSYLHTQRLA
VSFCLLCVYSCLTALVTVRDHQQRPLDVGPTAI-TLEPFCMALLCTLLACPVAQLLSLLF
RCSKEARGD-MQASTQ--WPLR--GVKTETPQGHDSS--------GR---PDSRQP---S
PHPTSDLLPWNDQAWRIAAS--------------SSA---VVCSP-FP-MEACSHKHH--
DLREKS---HYSPPSSQAP--GSGFEEL-GSQKSRVCLLWSSSVAWAISGSASLACGLGT
GFLGYWFVPAQCMWWLYLLLLSLVCCAFITQPLMICL-AALVFAWKRKHDSK--------
---FFTESLQDATKGL-DLELEEHSRTRV----PLSPISYSPDTAEEAERVLATRQRERH
LRW--AQTPSKAKLRVTGERLRRESIMQAALR--DMTTHSIMLLLLLFIAYGRFCPG-EI
SLNHAIRKAFTRKANHSLGDLSSTEDWWDWTLSTLLDELYPERTSA-RAWGAQPGALGGQ
CHLIGPPVVKLLKISAGTACTPPRPFSELVEDVLPMHSNDL--D--------LENQNVSP
-GGP------ETCG----VKK-ES

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2880)

YMHSLGKTRH--EAHAALTALRASKWIDHSTRAMSV
HFTLYNPPTQLFTSVILGTECLPSGGLVPSFLVESFRIFYSDSALKYLL--------MLS
E-LLFLVLNVIHLCFQLWGMTTKGILSYWRKPRHWLELSMVGVAIAYYAASGHLTTLAVN
ITDQFHKGLYQRLVDIGLMVSWHQRARCLQGILLFLWMLKYVHLLSSLSTMTPFSA---V
TCFP-----LFRVLLVGALLLAAHYHS-RWFLL-FTGTLSH-GTSAEAFPG--LLLQFPG
RSKKDSWHNC---LKSDHGVMRCYY--GTLFLLLATLGFRMLRATFLTVFQNR-KSSHRK
PLVTLKDIAVYTWHKVLTLLGLETT-LEETEVATDHIY-YLD-EFSSLLDELLMKIDGLS
DSLELSILENQWK-----RALESRAGDSPPVGSS-EYQATGVSGPLAAE---------SE
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------FSDPP--PGIRHTCNLSASWYHPESSSPLTR
YPPRAVLVTQPENAGYFAICCFPETDAQAPPALGIRVHVASGTALCLLLDFGDSCGAQMR
LCTVTGAATVTGYHQYRKEGV---------------------------------------
-------------------------------YKLKA-VIHDFHGA-EELGPYYMDIGHGS
VSVFMNSSSIHESEALSFADSLPQQRGTVVVHCFSSNSSYNVSFISQTQVGSGQAWRGVP
VRYKMQSVSVYTNGTVFAADTNITFVAITEETIPLEFAWYFGENPPVTTTSRGIR---RR
LSIPQWYHVKVKAISRIGSVVSEPHVIRVQKRIVANRLMSTAS

PF00801 // ENSGT00700000104221_7_Domain_1 (644, 704)

ALVNANVSFECRLNFGT
DVAYLWNFGDDTIELGSSSSSHVYSREGEFTVEVLAFNNVSSA

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVGEPCQPPP
VKNLGPAKVQIWRSQPLRLGVTFEAAVL

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1394)

CNISQGLSYSWSFVGAETTTVTLPAAINTHRQ
TIMLPGYTLECGNYTAIAKVQIKGSMVYSNYSVGVEVRARAPVSVISEGTHIFISKA---
TSTFIILRGAQSFDP-----DNPGAALRYHWTCTAASSPRWPCFDNSTSHQVDTQAPAIA
FPARWLSECCDQFLVTLTVSSRGQNSSQALLFLSTRPDLAFRFV--HISWDNFRDISVNW
NEEVSLRAVCEDCGDVPDLTYSWDLFLVNATEKSEVQVPFCSTVGLLGASAL-GASLK--
-SDLPSN----------------LR-ASPTPHSSEPSPMPLGGTALSNLG-----SISAE
STAGGHHIPASGPVAGSG-----EPVEDYGSLS----SLTEEALMMNSP------EGSWP
SPSSSTDFDDFEAYYSDIQEAV-LSLGRQPGT--STN-FQEAGPSLSA--E-ESA--NYG
DNLLGPFLHTDRAKPTLMIDWPKALVNQAVFYGYTTS-GIMGPAVTIKPFSLSSGETYVL
QASVASK--HVLLGKAQLYLTVNQAPQDLSCQVRPHHGM--EAYTIFSVFCMSGKPDFHY
EFRYWIGNTS-SRTLYHGQDTQYYFLLPAGDSLDNYKVIVSTEITDGQGSKVQPCTVAVT
VLPRYHG-----NNFCDKDLYNSILENLSTLQLVGSYMEIRNYITMITG-ILNRLYLESR
NTSSCGQWSQIQDVLISSACQVPYTDQEAMMDSIHILRDLISFPNKLSLTSAMCIFKYAK
MFLAQG---QFSRRLLTNKKLRVDFVLLI-SEVWEAAKED-VRN-GDYLQEEGMKIISDM
LL----------IHISTGHMEFQTVLHHSHESSIQNLGFIQVHFPSDLA-LHSTTQEETQ
SSCYISQLMFFMKSPYLGAQVSG-QVGGV-VIPRLYSCKSRRPILRGQLETPVTMEFGE-
-EDYL-HKRNPAMCVLLRDEVNVHRFT-GLSENSQESLQIHIKFSQPVTRAFPIMLLVR-
FSERATPSDFLVKRVYFWDEQTVQMYVPAAPWKG-------ANVGYLSLLDADYDRKPPN
KYLAGAVNYTVHFQWIQCVFWDK-TEWRSEGLSPQPGSSTEKVNCSYHQLA-PVSVLRRK
LNATLEVSSISEFQSHPHNLLPGIFSVFFLVLYGFLVSKSRCIDCQEKKNPGFIFLEEDA
P-PGYQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2049)

YAVVIDTGFRSPARFTSKVFI---VLCGEKGCSETKELCCPEK-PLFG-----
-RNSRHTFILSTPHQLGPLQKIRLWHDSSGPSPCWFISHVMVKELCSG--QAWFFSAQCW
LAVSKSGG

ENSGT00700000104221_7_Linker_6_7 (2049, 2665)

HVLREFFCRSHGLGFWKLFYSKFTEYLEDFHIWLSLYSQPPSSSYLHTQRLA
VSFCLLCVYSCLTALVTVRGHQQCPLDVGPTAI-TLEPFRLALLCTLLACPAAQLLSLLF
RCNKEARGH-LRASTQ--WPLR--GVKTEIPQGPDSS--------ER---PDSRQP---S
PHPTSDLLPGTDQAWRIAAS--------------SSG---EVCSP-FP-LEACRDKHP--
ELREKS---HYSPPSSQAL--SSGFEEP-GSQQSRFCLLWSSSVAWAISGSASLACGLGT
GLLGYRFVPAQSMWWLHLLLLSLVCCAFITQPLMICL-AALVFAWKRKHDSK--------
---FFTESLQDATKGL-DLELEERSRTRI----PLSPISYSPDTAEEAERVLAARQRERH
LRW--AQTPSRVKLRETRERLRRESLMQAALR--DMTMNSIMLLLLLFMAYGRFCPG-EY
SLNHAIRKAFIRRANHSLGDLSSTEDWWDWTLSTLLDELYPERTSA-RAWGAQLGALGGQ
CHLIGPPVVKQLKASAGTACTPPRPFSELLEDGLSMHSKGL--V--------LEDRNVTP
-GGP------ETCD----VKK-ES

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2915)

YMHSLGRTRH--EAYAALTALRASKWIDHSTRAMSV
HFTLYNPPTRLFTSVILGTECLPTGGLVPSFLVESFSIFYSDSALKYLL--------MLS
E-LLFLALNMIHLCFQLWGMATKGILSYWRKPRHWLELSMVGVALAYCAASGHLSTLAAN
ITDQFHKGLYQRLVDIGLMVSWNQRARCLQGLLLFLWMLKCVHLLSSLSTMTPFSA---V
TCSL-F--RVVVPVLVGALLLAAHYHS-HWFLL-FTGTLSR-GTSAEAFPG--LLLQFPG
RSKKDSWHNR---LKSDHEAVLCSY--GTLFLLLATLGFGMLRATFLTVFQNR-KSFLRK
SLVTLEDIAVYMWHEVLTLLGLGTT-LGETEVATDHIY-YLD-EFSSLLDELLMKIDGLS
DSLELSILENQWR-----RALESRAGDSPPGGIT-EYQTTGVPGPLEAE---------SE
-------------------

--------------------RCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMRHGKCDCPRCALKTKAEDRESQSPSSLPSGQKNIWKTTSKAALSVVNE
KTQAVVNEKTQAPLDCDHSADRILHKPSIIIARVWSSGGPRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAAPCSLKMEASCCVLRLLCCAEATAMGL----LPGTVTMETPTKVARPTQ
TSS----KRVPLWPIS-----HFPTSPRSSHSLP--PGTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQNSDNSMNSVLDCSLEMEARAPPNLGFRVHMASGEAVCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYS--KVFF-FLLLHFHLDISTYKE---------------------
-------E---DSDPSNLGYY---------------------------------------
--------SVHEDEVLVFTDSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSVT
VWYRMQSISV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDITFTAVTKETIPLEFQWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCEPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTVLAKVQIEGSVVYSNYCVGLEVQAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDPD-----NPGATLRYHWECTTASSPAHPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTVDPD-ATTTPFSREPSLVTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGPLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FLESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPALMIDWRKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTVFSVFCMSGKPDFRY
EFSYQIGNAS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLAEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCHQWSRIQDALISSVCKLAFVDQVWPRGGQEMRPR---------------------
-----G---PASSVPIHGCGLSSQLIYITNECCWFVK-----------------ERMTKS
IIGCLPLN-----HVSTGQMEFRTLFHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGMETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGPDNRRNKTTFILLRDKVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLLKQIYFWDEPIVQIYIPAASQKD-------VNVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVTCSYDRLA-AFGLLRRK
LKASFEVSDISKLQSHPENLLPSIFIIGSLILYGFLVAKSRQVDHHEKKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSTPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGRLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFTLLCVYACLTALVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAEPHC-PPRG--EAQAEAPQGPNS---------CRR-IPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSGT
ALMGKS---HCSLPCTQAP--NSGLEGL-MPRWSRALQPWWSSAVWAICGTTSLACSLGT
GFLGYRFGQEQCVWWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----PFSSSCSVPDYAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISMDILMLLLLLGIMYGRFSQD-EY
SLNQAIRKEFTRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVLGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPRPFSAPTEDSIPTCSPKG-GGPENPYLIDPENQNMTL
-NGP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2898)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------VLP
Q-LVFLALSLVHLCVQLYHMMDKGFLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMISWNQRARWLQGILLFLFTLKCVYLPGIRNTMASCSS---M
TRHSLP--SIFVAVLAGALILAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYL--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKTLTFLRLETPKLEEAEMVEYHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENISN-----STGEARAEESPLVDIS-SKQATEVRPCKIIYVNFLYSNLSSK
GVLEYLFFQIIRSICINIL

------MAKEGVKGISDDQERSLPAACSLCLPGQGPASAEDCGGLRLCCCSHSPPHGGAG
VE-VRASHVCFMSDEKHGCPPSASQGQEGDQESQDPSPSAAWEKNILKTASKGVLS----
-----VNGKTEASLDWDDVADRTPHAPSVTIPSVWSGSGPRSCHWWLCATGKADRAFFGL
LQ-VQGTSSAAAPCSSKTEASCCVLGQLCGAEGMARQQ----LPGTVTMGNPTTAAGPAQ
TST----QQPPLWPISRFPTFPR-----SSHGLP--PGASHTPSLSATRSGPKRLCPIIP
RPPGAIPAQDHDNAMNRVICHFPETEAQAPPNLGFRVYVASAVALCLVIDFGDSSRVEMR
VHDMSEATVVTAYHQY--------------------------------------------
--------------------------GTEGVFVLKAVIYYEFPGAEVELGPYYVEIGHEA
LSVFMNSSSVHEDEVLEFLGSHMNQKSTVVVHRFPSIPSHNVSFISQTRVGDSQAWLSVT
VWYKMQSVSVYTNGTVFAADTDIVFAAVTKETAPLEFVWHFGEDPPVRTTSRSIK---KR
LSIPQWYRVTVKASSRLSSVVSKPHLIRVQKNIVANRLLS

PF00801 // ENSGT00700000104221_7_Domain_1 (641, 704)

PSSALVNASVAFECRINFGT
DVAYLWDFGDGTFTPGSSSISHVYRREGEFTVEVRAFNNVSTA

ENSGT00700000104221_7_Linker_1_2 (704, 752)

TLRKRLFIVRKPCQPPL
VKNMGPGKVQVWRSQTVRLGVTFETAVLCDI

PF02010 // ENSGT00700000104221_7_Domain_2 (752, 1407)

SQGLSYTWSLIDSEGSPVPLPAAVDTHRQ
TLVLPSHTLEYGNYTALAKVRIGGSAVHSNYCVGLEVRARAPVSVISEGTHLFVPRT---
ASPPIVLRGTQSFDP-----DDPGATLRYHWGCTAASSPGRPCSDSSTPHRLDTRAPTIS
FAAKWLSDSYDQFLVTLTISSGGRNSSEAQVFLSTRPDSAFRFV--HISWVNFKDTFVNW
NEELSLQAACEDCGEKPNLSYSWDLFLVNATEKNRMEVPFCRAAGLLGSLGL-GAILKLP
EPSPLSTEP----------SPTHPD-VTTTLFSRELSPKTLGRPALSVPG-----RTSAE
PTAGAPRILATVDSEVPG-----EAPKE-GPPDPEPGSQGEGSLMTSPS------ERSWP
PTNTAPYLSDFEAYYSDIQEAI-PSEGRQPGN--KSS-LPGSGPSLSA--EEESP--GEG
DNLVGPSLPKDRAVPVLLIDWPKALVGRAVFQGYTSS-GITEQTVTIKPYSLSSGETYVL
QVSVASE--HSLLGKAQLYLTVNRAPGDVACQVQPHRGL--EAHTVFGVFCMSGKPDFHY
EFGYQIGNTS-KHTLYRGRDAQYYFSLPAGDPSDNYKVLVSTEITDGKGSKVQPCAVVVT
VLPRYRG-----SDCLDEDLYNSSLKSLSILQLMGSYTEMRNYITMTTG-ILSRLSKEDG
TA-SCGQWSRIQDELISSVCKLAFADQEEMTDSVLMLRNLITFSNK--------------
----------FSGRCVADRGLRLELVLLM-SRVWDISKEEKLQS-EGYLREEAIIVISDL
LLGCLSLT-----HVSTGQMEFQTLLHQNLQSSVQSLGSVQVHLPGDLA-GHSPAGAETQ
SSCYISQLILFKKSPYPGGRAPG-QMGGV-VRLALYNCSSRRPIGRQWLRKPLTLEFEE-
-EDNPDHRRNKTTFVLLRNKVNFHQFI-GLSENPQESLQIEIEFSKPITRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDEQIVQMYIPAVSWKD-------ANIGYLSLLDADYDRKAPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSGSFSPQPGASPEKVNCSYDRLATAFSVLRRR
PNASFEVSDISKLQSHTENLLPSIFIVVFMVLYGFLVAKSRQVDRYEMKKTGYIFLQEAP
R-PGREL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGENGLSETKELYCPEK-PLFE-----
-RNSRHTFILSAPDRLGPLRRIRLWHDSRGPSPDWFLSHVMVKALHTG--QGWFFPGQCW
LAASRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFWKLFCCKFIEYLEDFHVWLSAYSRPSPSRYLHTPRLA
VSFSLLCVYACLAALVTAGGQEQLLLAVGPAGV-ALGSFRVGLLCALLASPGAQLLSLLF
RLSKEAPGP-SQAEPG--RPLG--GAHTEATPGPNS---------RRR-TPDAQEP---R
KHPASAVLSG--DTWRKAVS--------------GDS---AACPA-PE-LEARGTAHGGT
AVSRES---HHCLPRSQAP--RSGLEGL-APP-AGAHLPWSDSAALAVCGMASLACGLGT
GFLGYRFGPAQCVQWLHLLFLSVVCCVFVTQPLMICL-MALGFAWKRKDDNH--------
---FFTESLCEATRNL-DVELEEHSRTCL----PLSSSCAVPGCASEVEKVVAARQRARH
LRW--ARPPSMAQLKVTRERMRRESRMQAALR--DISMHILMLLLLLCIIYGRFSRD-EY
SLNQAIRKEFTRNDRNSLGGLRSMADWWDWSLTTLLDGLYPGGASVASRPGAQPGALGGK
CYLIGSSVIKQLKVSPSSLCKPHRAFSVLIEDSLPACSPEV-GGPGNPHLIDPEKQNVTP
-GGP------RGCG----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2895)

VLRLGRTRP--EAHAALAGLRASRWIDRSTSAVSV
HFTLYNPPTQLFTSVSLSVEILPMGGLVPSSLVESFSIFCRDSALRYHL--------MLP
E-LVFLVLNLVHFCFQLYGMMEKGVLNYWRKPRNWLELSVVGVSLAYYAASGYLATLAGD
VTDQFHRGLSQVFMDLTFMASWNQRVRWLQGILLFLLMLKCVHLPAIQETMVSCTS---V
MRCSLP--RAFAPVLAGALTLAAHSHL-RQLLL-STWALPS-STFADAFPG--LLFRFPG
GSPKDLFLGL---SKSDRRAMACYC--VALCAVTAALCSGMLRGSLMTLTQRR-KSFQSK
CLVRLKDVTAYTWGKALTFSGLEMPKLEETEMVENHSS-DIK-DSQ--------------
------------------------------------------------------------
-------------------

---MA---EEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNE
KTQAVVNEKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSAL
LQ-LQGTTSAAAPCSLKMEASCCVLRLLCCAEDVATGL----LPGTVTMETPTKVARPTQ
TSS----QRVPLWPIS-----HFPTSPRSSHGLP--PGIPRTPSFTASQSGSEILYPPTQ
HPPVAILARNSDNFMNPVLNCSLEVEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGI---FFHLLHFQLDMSTYKEAETQ-----NTTLNVYLCQSE
NS---CLE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEVELGPYYVEIGHEA
VSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECWINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 751)

TLRQQLFIVCEPCQPPL
VKNMGPGKVQIWRSQPVRLGVTFEAAVFCD

PF02010 // ENSGT00700000104221_7_Domain_2 (751, 1407)

ISQGLSYTWNLMDSEGLPVSLPAAVDTHRQ
TLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTQSFDPD-----DPGATLRYHWECATAGSPAHPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFV--HISWVSFKDTFVNW
NDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISESS
QLNLLPTEP----------GTADPD-ATTTPFSREPSPVTLGQPATSAPR-----GTPTE
PMTGVYWIPPAGDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGRS------ERSQP
THSPDPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPGSGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSS-GITEQTVTIKPYSLSSGETYVL
QVSVASK--HGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGKGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLVSFSNKLGFMSAVLILKYTR
ALLAQG---QFSGPFVIDKGVRLELIGLI-SRVWEVSEQENSKE-EVYRHEEGITVISDL
LLGCLSLN-----HVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLA-GHSPAGAETQ
SPCYISQLILFKKNPYPGSQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGLDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPN
RYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYHRLA-AFALLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEAS
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQPHLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGS-ARVEPHS-PLRG--GAQTEAPHGPNS---------WGR-IPDAQEP---R
KQPASAILSGSGRAQRKAAS--------------DNG---TACPA-PK-LQVHGADHSRT
SLMGKS---HCCPPHTQAP--SSGLEGL-MPQWSRALQPWWSSAVWAICGTASLACSLGT
GFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLCEATRDL-DSELAERSWTRL----PFSSSCSIPDCAGEVEKVLAARQQARH
LRW--AHPPSKAQLRGTRQRMRRESRTRAALR--DISMDILMLLLLLCVIYGRFSQD-EY
SLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGK
CYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEV-GGPENPYLIDPENQNVTL
-NGP------GGCG----TR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2903)

VLSLGRTRT--EAHTALSRLRASMWIDRSTRAVSV
HFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------MLP
Q-LVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGD
VTNQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS---M
MRHSLP--SIFVAGLVGALMLAALSHL-HRFLL-SMWVLPP-GTFTDAFPG--LLFHFPR
RSQKDCLLGL---SKSDQRAMACYF--GILLIVSATLCFGMLRGFLMTLPQKR-KSFQSK
SFVRLKDVTAYMWEKVLTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKTSN-----NTGEARTEESPLVDIS-SYQAAEPADIKDF------------
-------------------

---MA---EEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNE
KTQAVVNEKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFYHRRLCATGTADSIFSGL
LQ-LQGTTSAAAPCSLKMEASCYVLRLLCCAEDVATGL----LPGTVTMETPTKVARPTQ
TSS----QQVPLWPIS-----HFPTSPRSSHGLP--PGIPRTPSFTASQSGSEILYPPTQ
HPPVAILARNSDNSMNPVLDCSLEMEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMVVTAYHQYSKGN---FFHLLHFQLDMSTYKEAETQ-----NTTLNVYLCQSE
NS---CLE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEVELGPYYVEIGHEA
VSAFMNSSSVHEDEVLVFADSQVHQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDIIFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRISSVVSEPHIIRVQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECWINFGT
DVAYLWDFGDGTISLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 754)

TLRQQLFIVCKPCQPPL
VKNMGPGKVQLIFLV---------EMGFCH--I

PF02010 // ENSGT00700000104221_7_Domain_2 (754, 1412)

GLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSRIVLRGTQSFDPD-----NPGATLRYHWECATAGSPAHPCFDSSTGHQLDATAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSAFRFV--HISWVSFKDTFVNW
NDELSLQAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISESS
QLNLLPTEP----------GTADPD-ATTTPFSREPSPVTLGQPAPSAPR-----GTPTE
PMTGVYWIPPAGDSAVLG-----EAPEE-GSLDLEPGPQNKGSLMTGPS------ERSQP
THRPDPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPGSGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSS-GITEQTVTIKPYSLSSGETYVL
QVSVASK--HGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTIFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLQNLSTLQLMGSYTEIRNYITVITR-ILSHLSKGDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLGFMSAVLILKYTR
ALLAQG---QFSGPFVVDKGVRLELIGLI-SRVWEVSEQENSKE-EVYLHEEGITVISDL
LLGCLSLN-----HVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGSQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDDLDNRRNKTTFVLLRDEVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPN
RYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYHRLA-AFALLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEAS
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQPHLDISP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGS-ARVEPHS-PLRG--GAQTEAPHGPNS---------WGR-IPDAQEP---C
KQPASAILSGSGRAQRKAAS--------------DSG---TACPA-PK-LQVHGADHSRT
SLMGKS---HCCPPHTQAP--SSGLEGL-MPQWSRALQPWWSSAVWAICGTASLACSLGT
GFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCL-MALGFAWKRRADNQ--------
---FFTESLCEATRDL-DSELAERSWTHL----LFSSSCSIPDCAGEVEKVLAARQQARH
LRW--AHPPSKAQLRGTRQRMRRESRTRAALR--DISMDILMLLLLLCVIYGRFSQD-EY
SLNQAIRKEFTRNARNSLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGK
CYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEV-GGPEDPYLIDPENQNMTL
-NGP------GGCG----AR--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2903)

VLSLGRTRT--EAHTALSRLRASMWIDRSTRAVSV
HFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHL--------MLP
Q-LVFLALSLIHLCVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGD
VTDQFHRGLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSS---M
MRHSLP--SIFVAGLVGALMLAALSHL-HRFLL-SMWVLPP-GTFTDAFPG--LLFHFPR
RSQKDCLLGL---SKSDQRAMACYF--GILLIVSATLCFGMLRGFLMTLPQKR-KSFQSK
SFVRLKDITAYMWEKVLTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKTSN-----NTGEARTEESPLVDIS-SYQAAEVRPCKIIYVNFLHSNLSSK
GVLE---------------

---------LVDEGVDIFGGPNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXX
XX----XXXXXXXXXXXXXXXXX----XXSSSLP--LEAVNIHSLSAPQSGPQEPCPCTD
CHYGAIPIRDHAVTIDAAIHGYPETDVWAPKNLGFRLHIASKAACCVVTDFGDGSGVQMR
IHNMSEEMAFTTYHWYRKXXXXXXXXXX----XX-XXXXXXXXXXXXXXXXXXX------
X---XXXXXXXXXXXXXXXXXXXXXXXXXGVYMLKTVIYNECYGTEVELGPYYVEIGHET
ISVFMNSSSIHANEVLIFAGSTLDEKYSVIMHKFPSISSYNVSFASSIQMNDGLRWYSAI
VWYQMQSIS

PF00801 // ENSGT00700000104221_7_Domain_0 (550, 627)

VYTNGTIFATETDITFVAVTKETTLLEFIWYFGEETPVKTTSRNIK---KK
LRMPRWYQVTVRASNGISSVVSEPHH

ENSGT00700000104221_7_Linker_0_1 (627, 638)

IRLQRRIRANR

PF00801 // ENSGT00700000104221_7_Domain_1 (638, 711)

LASSTSALVNASVIFECRINVGT
DVSYLWDFGDGTVDLGNSSASHVYSREGEFTVQVLAFNNVSAASLQKRLFVTLKPCQPPP
IKNMGPRRVQVWRSQPVELGVTFEDTVLCDISQVLSYSWSLRNSTGWPVPLPSTISMHKQ
ILVVPRYFLEPGNYTALAKVQVEGSIVHGNYCVEVEVQGRAPVSVISEGTHLFISRT---
S--VVILRGTQSYDP-----DYPEATLRYYWKCTVTSTREHPCFTASSPHSLDTRTSALI
FTANSLSDSYDQFIVSLTVSSAGRNSSETRVFLSTRSDSALRFV--HISRVNFKDIFVNW
NEELSFQVECEDCSEITNLSYSWDLFLVNATKKNNIEVPFCRTVGLLESLRF-GTVSNIL
ELNSLSVEQ----------KRADLS-ERTMPYSWELL-KTLGKGTSMDPE-----SLSME
PPGSTHQTSASSSTAA-------------------PVSWNKGPLSSQPS----------S
RESPSLHLPDSEAFYSDIQEAV-PSERRQPXXXXXXX-XXXXXXXXX---XXXXX--XXX
XXXXXXXXXXXXX--XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXSK--HHLLGKAQLYLAVNQAPKDVSCQVLPFQGL--EAQTIFSIFCMSGKPDFYY
EFSYQIGNTS-KHTMYHGRDAQYYFALPAGDPTNNYKVLVSTVIRDGQGSQVQ-CAVEVT
VLPYFHG-----TQCP-EDFYNSSLKNLSTLQLMGNYLEIRNYIAMITR-VLSRWAKEDS
-S-SCGQWSQIQDTLISLVCRLEFTNQEEMINSVLMLRDLIGFPNKLSFKTAVHILKYSR
MLLTQN---QYSVKFEVDKRSMSELILLV-AEVLEVSEKEKSK---DYLREEGNKIISDL
--GCLCLNKGSDLYMSSKQVEFRVLLHHEFQSSLQSLGSIQVHLPADIA-THRPSATEME
SLLFISQLMLFRKNPYLEGQAPG-QIGQV-ISFSQYNCSSRRPVRRQRLKNPLTVDFPE-
-ETDLENVRNKMTFILIQDKVNFHKLF-GLSENLLETLQIRIEFSKPITSVFPVMLLVR-
YFEKPTPSDFLMKQIYLWDASVVHIYLPAVLQKX-------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXHPENLLLSIIVVIFILY--FMVIKSKQVDHREKRKMGYIFXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXX

PF01477 // ENSGT00700000104221_7_Domain_6 (1946, 2053)

VYI---VLYGENGLSEPKELYCPDT-PLFE-----
-SNSRHTFILSAP-VLGTLQKIHLWHTSSGSSPAWFVSHVMVKELHRGQGQCWFFPAECW
LSVSQWDGCVER

ENSGT00700000104221_7_Linker_6_7 (2053, 2535)

ELACLCWGLGFWKLFYSKFAEYLEDFHVWVSVYSRPSCSGYLHTQRLT
VAFTVLCTYMCLAALIIAAGLEQLWLDAGSTSG-TWGYFQTGFLCSLLVSPGAQLLSLLF
RLSKEPSGY-FSAEPLL-PLKRVWT---ETAQ--GPN--------SLKRMPDAPET----
------------------------------------------------------------
----------------YKP--QVRLEALTMPRCLRIPWPPLGSVAWTVCGTVSMACGMAT
GLLGFRFGPAQCVQWSCLLTVSIVCCVLLTQPLMIGL-MALSFAWKRKNDKH--------
---FFIESLHAATRHL-DSELVGSPKTCT----PLSSTCSIPNYASEAEKALAARHQARC
LRW--ARPPSIAQLRVTRSRMRREMRARKALR--DIYMHVVMLLLLLFIIYGTFSQD-EY
FLNQAIRNEFTRSV

PF08016 // ENSGT00700000104221_7_Domain_7 (2535, 2963)

RHSMGGLSSMDDWWHWSLTTLLDGLYRENSSAVHTPGPQPMALGGK
CYLVGTLVIKQMKVPQSGLCQLSGSLPMPFQDSFPTLNPRI-RDPTILSTIDPEIQNVAG
-S----------------SR--DDCEFHLGSTRP--AIRETLLDLRARKWTDHRTRAVSI
YFSLYNPPSQLFSSVSLTAEVLPTGRLTLSALVESFTIFHSNSSLQSYR--------MPL
E-LLFLVLSLIQLCTELYDMIESGVYSYWQKPRSWLELSMTGVSLVYHIASSHCLTLTRE
VMDQLHKGLFQGFVDLSHMASWNQRARWIRGILSFLLILKFLCLLGIQKTMTFM------
-RLSLS--FVIAPGLVGVLMLAAYFHL-HGFLL-FTKTLTS-GTFSQSLHG--QLFHFPG
RSQRDSFLGS---SIYDQHYKAWFYGKGAFFILMTPVWFGMLRGSLMTLSHN-RKYFQRK
FLVLLKDVAAYMWGKVLTFS---ESPKEEIQVVENHNC-FLD-EFEDLLDELLLKINGLS
DCLEFPLLEQQSE-----YMLETNAEDIPLVSIF--------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

PF02010 // ENSGT00700000104221_7_Domain_2 (800, 1407)

VQIQGSVVHSNYCVGVEVQSRAPVSVISEGTHLFIPRA---
TLTPIILQGSQSYDP-----DYPGAALRYHWTCTAANSPGQPCFDNSTPHQLDTGAPTIS
FTAKWLSECCDQFLVTLMVSSTGRNSSKAEVFLSISLAFAFRFI--HISWVNFKDIYVNW
NEELSLQAVCEDCGEIQNLSYSWDLFLVNATEKNRIEVPFCSTVGLLGASAL-GTTLKSS
D-------------------------GSPTLSSREPSPMIHGRLALLVTR-----STSTE
STVGGHQIPASGDNTALE-----DPSEDE-PLGPELESLGEGASTVSPS------ERSWS
PPSFSPVLDDFEAYYSDIQEAM-PSRGRQRGN--YTG-LPGSGLSTSA--EEESP--GEG
DNLVGPFLLAGRAEPALVIDWPKALISRAVFQGYTSS-GITEPIVTIKPYSLSSGETYVL
QASVASK--QDLLGKAQLYLTINPAPQDMACHVQPHHGL--EAHTIFSVFCMSGKPDFHY
EFSYQIGNTS-KHTLYYGRDTQYYFALPAGQPSDNYKVMVSTEITDSKGSKALACSVAVT
VLPRFHG-----KDCLSEDLYNSSLK

ENSGT00700000104221_7_Linker_2_5 (1407, 1816)

NLSTLQLMGSYMEMKNYVTMITG-ILNRLVKENR
NT-SCGQWSQIQDALISSVCKLAFADQEEIIHSVLMLRNLISFSNKLSFLSAVHILKYTR
SLLAQG---QLLGRFVVDRQLRLELILLI-SGVWEASAQEKFRN-ENYLQEEGMKIISDN
HL-----------IVNTGQMEFQTLLHHNLRRSIQNLGSVQVYLPGDLT-GHSSAQEGMQ
SLCYISQLVFFKKNPYPEAGAPG-KVGEV-VGLTLYSCSSRRPIHRGRLNTPLTVEFGE-
-EDSPDNKRNKTKFILLREKVNFHQFT-GISPKPQESLQIRIEFSKPITRAFPVMLLVR-
FSKKPTPSDFLVKQIYSWDEQIVQIYIPAVPQKG-------ANVGYLSLLDADYDRRPPN
KYFAKAVNYTVHFQW

PF01825 // ENSGT00700000104221_7_Domain_5 (1816, 1857)

IQCVFWDK-REWKSESFSPQPGTSPEKVNCSYDHLA-VFSV

ENSGT00700000104221_7_Linker_5_6 (1857, 1928)

LRRK
LKAGFEVSDISSLQHHPQNLLPSIFIVIFMILYGFLVTKSRCIDNHEKKKMGYIFLQEYT
P-PGHKL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2045)

YAVVIDTGFRAPARFTSKVFI---VLCGENGLSETKELCSPEK-TLFE-----
-RNSRHTFILSAPAQLGPLRKIRLWHDSRGPSPSWFISHVMVKELYSG--QSWFFPAQCW
LAAD

ENSGT00700000104221_7_Linker_6_7 (2045, 2665)

QWDGHVERELTRLRHGLGFQKLFYSKFTEYLEDFHVWLSVYSRPSSSGYLHTQRLT
VSFCLLCVYAFLAVLVTAGEHEQLSLDVGPTDI-TLRSFSLGFLCTLLASPGSQLLALLF
RLSKVPVDY-LHSPML----LN--GTIVEE---FTIC--------GNI-DLGLSLS---F
QHSVSAIPSGSDR-SRRKAE--------------GNG---TACPS-MD-LEVCRPDHQGT
LQREKS---HHSPPGLQAP--KGGFEGL-MPQWSRAGMPWSNSAAWAICGSASLACGLGT
GLIGYRFVTAQCMRWLHLLSLSVVCCVFVTQPLMICI-MALGFAWKKKDDNQ--------
---FFAESLCEATRNL-DSELEERSRTHV----PLSHSCCISDYAKEVEKVLAARQQERN
LRW--VRPPSKTQLRVIREKIRKKSRTEAALR--DISMYILMLLLLLFIIYGKFCPD-EY
SLNQAIRKEFIRQ---SLEGLRSTDDWWDWCLTTLLDGLHLGGPSA-----AAPGALGGK
CYLIGTSVIKQQKVSLCRIHKPPRPFSALLEDSPPTCSPAI-GG--------FENQNVTP
-GGP------RVWG----LRK-ED

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2896)

FVLSLGRTRP--EAQEALNALRASRWIDHNTRAVSV
HFTLYNPPTRLFTSVTLSAEVLPTGDLVPSSLIESFRIFRGDSALWYSL--------VLP
E-LVFLVLNLIHLCFQLCRMVEEGVLDYWQKPRSWLELSVIGVTLTYYTASSHLTTLAGD
VADQFHKGFCQVYVDLSLMALWNQRTRWLQGILSFLWILKGIYLLGSLNSTVNLVT----
----TT--MLFSLQLMGALLLATHSHL-HWFLV-FTWTLTS-VTFADSFPR--LLFHFPL
RSQKDSFHSL---SESDQEDMAPYC--GALFLLTAMWCFGMLRGSLVTYFQKR-KSSHSK
SLVRFKDITAYTWVKALTFLGLEMPKPEEAQVVADHNY-YWD-EFASLLDELLMKIDGLS
ESLELSLPEKQHR-----STVEARAEESPLVGVS-GYQATE-------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------V

PF02010 // ENSGT00700000104221_7_Domain_2 (798, 1393)

FQVQIKGSMVYSNYCVGVEVRPRAPVSVISEGTHIFIPRA---
TTTPIILRGFQSYDP-----DNPGAALSYHWTCTAASSPRWPCFEDSTLYQMDTHAPSVS
FQARWLSECCDQFLLTLTVSSNGQNSSQALIFLSTHPDPAFRFV--HISWANFRDIHVNW
NEELSLRAVCEDCDNVPDLTYSWDLFLVNATEKNMVEVPFCSTVGLLGSSAF-GALLKLS
QSGLQSN----------------PR-GPLTLHSPQRSPMPLSWTTLPNLG-----STSTE
STAGGHHIPVVGPLAGSG-----EPMEDYGSLSPAPGSSDEQALMMSTP------EGSWP
PSSSSPAFDDFEAYYSDIQEDV-PSLGRQPGS--GTN-FQESGPSMDA--E-ESA--SDG
DNLLGPFLHTGREKPAFMIDWPKTLVSRAVFHGYTSS-GIVGPAVTIKPFSLSSGEMYVL
QASAASK--HALLGKAQLYITINQVPRDMSCQVRPHSGL--EAHTIFSVFCMSGKPDFHY
EFRYQIGNTS-PHTLYRGRDTQYYFLLPAGETLDNYKVIVSTEITDGQGSKVQPCTVEVT
VLPRYHG-----NDCPDKDLYSSTLETLSSLQLVGSYTEIRNYIAMTTA-ILSRLYVESK
NTSMCGLWSQIQDVLISSACKLPSTDQEAMMDSIHILRDLINFPNKLSWLSAMHILKYAQ
MFLRQG---QFSRKLLVNKKLGIELILLI-SGVWEAARED-KRN-GDYLQEEGLKIISDT
LL----------LHISTGQMEFWTVLHHSFQSSVQNLGFIWVHFPGDLA-LHSSALEESH
SPCYISQLMVFMSSPYPAGQAPG-QVGGV-VSPRLYSCKSRRPILRGRLKTPVTVEFGE-
-EDHR-HKRNPTMYTLIRDEINLHQFI-GLSEKPQETLQIQIEFSKPVTRAFPIMLLVR-
FSKKATPADFLVKQVYFWDEQTVQIYVPAVPVKG-------TNVGYLSLLDADYDRRPPN
KYLAGAVNYTVNFQWIQCVFWDK-TGWRSEGPCPHPGSSPEKVNCSYHRLA-PFSILRRK
LNATLEMSSISGFRSHPHNLIPGIFSVFLLVLYGLLMTKSRCVDCHKKKKPGCIFLEEGI
P-PGHQLYA

PF01477 // ENSGT00700000104221_7_Domain_6 (1930, 2045)

VIIDTGFRSPAQFTSKVFI---VLYGENGFSGTKELCCPEM-SLFG-----
-RNSRHTFILSTPNQLGPLQKIRLWHDSSGPSPNWFISHVMVKELHSG--QGWFFLAQCW
LAVS

ENSGT00700000104221_7_Linker_6_7 (2045, 2668)

LCDGRVQRELFCLRRGLGFWKLFYSKFTEYLEDFHIWLSLYSQPTSSSYLHAQRLA
VSFCLLCVYSCLTALVTVGVHEQRSLDVGPT----LESFSLGLLCTILACPATQLLSLLF
RFSKETAGH-LRDAPQ--WPLG--GVKTEAPQGSDHS--------GR---PSLRQP---F
QV----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------LAARQRERH
LRW--AQLASRAKFRVTKERLKKESQLQAALR--DISMHSLMLLLLLFITYGRLCPG-EY
SLNQAVRKEFTRNARYSFGKPSSTDDWWDWTVSTLLNGLYPEGPAA-GAWGAQPGALGGQ
CHLIGPSVIKQLKVSSGTACTPPRPVSELMEDALSTSTRDL--D--------LENPNVTH
-GGP------EACG----VKK-ENSMH

PF08016 // ENSGT00700000104221_7_Domain_7 (2668, 2903)

SLGRTRH--EVHSALTALRANRWIDHSTRAMSV
HFTLYNPPMRLFTSVTLGAEFLPMGGLVPSSLVESFSIFYSDSVPQYLL--------MLS
E-LVFLVLNMTHLCFQLWGMATNGVLSYWKKPRHWLELSMIGVALAYYAASGHLTTLAKN
VNDQVHKGLHQMSVDLSLMVSWNQRARWLHGSLLFLWILKCAHLLGFLNTMTSFSE---V
TCSSLS--RAFAPALLGALLLAAHSHL-YRFLL-VTWTPSS-STSTDAFPR--LLLQFLG
RSQRDSLNNH---VEPDHQAMACYR--GALFLLVATLCFRMMRASLLTFFRKG-KSFHRK
SLVILKNVAVYAWRKFLTLLGLETTTLEETGLATDHSY-YLD-EFSSLLDELLVKIDGLS
DNLELSILEEQWR-----RTVEARAVDSPLVCLS-GCQATGVAGSLDAE---------SS
-------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------PSVTITSFWNSSGPDPCRPRKCAVGPGSSVPCGL
LQELQRSCPPAGPCRLRVRIPSCP-----SADDVPSDV----LPGTDVASTAASPGVPVR
PAVSAPTSSPTA--HPPTLPRS----------CPASPHSSLGHGGSASWPRP-----PTR
CHPGAVSMHSPPDALDAADHGFPDTDARAPLSLGFRVRASPKAALCLQVDFGDSSGVQVT
IYNVSRGIAVTAYHQFRKVMCFLHFFHW----PR-ECARLH--PLGPRAMSERGALCE--
----QELSDARDRGASQRCCTLPASCAWQGVYVLKALIYNDLCGPGRELGPYYVEMGPAT
MSVFMNSSSIRRDELLVFAGSHADQKSTVVTHHFAAGPPCNVSFTCQSCAAGGQAWPSVT
VQYRMQPVSVYTNGTMFATDIDITFLAVMDERHPLPFSGVRGPLPTSDLSDLLLSPPGPV
HGSHCRYSVTVQAASRLGRVASEPRRIRTQRRIVANRLVS

PF00801 // ENSGT00700000104221_7_Domain_1 (641, 704)

PLSALLNASVTFTCRLNFGT
NVAFLWDFGDGTVGPGGSSAHHTYQREGQFTVQVRAFNDVSAV

ENSGT00700000104221_7_Linker_1_2 (704, 749)

SLAKQLFVVREPCQPPP
VKNMGPGKVQVWRSQPVTLGVTFESAIL

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1384)

CDISQGLSYTWTIRTSEGWPVPLPPGVSTRRQ
TITVPGYFLELGNYTALARVQVDGSVVHSNYSVGVEVRARAPVSVISEGTQLFISRA---
PSVTIILSGSQSYDP-----DNPGATLRYHWTCTAAGAPGEPCFTASSPHSLRAGAPSLS
FPASSLSNSYDQFLVTLTVSSAGRNSSEAQVFLSPRPDTALRFV--HISRGSFKDALVNW
NEELSLRAECDACAAGPRLSYSWDLFLVNATEGTRTDGPFCRAVGLLGAAGL-GADSMQL
PSSAPSTAA----------SCPEPR-GTGVASSQKQSPQPRVQPGPSLPG-----TPSLG
PV-DTHPLPDAGDAAFPG------LARRFA-GS--PGTWSPWSPSPSPS--AAW----QM
SPPQGPRASDFEADYGDIQEAV-PPTGRQPAHWSGAS-LPGADPSSS---PGGGQ--GDG
DNLLGPLRPA--AGPALMVDWPKAPVGRALFRSYTAS-GITGHAVTIKPFSLSPGETYVV
QASVAST--RGLLGRAQLYLTLHPAPRDVACQVQPHRGL--EAHTVFSIFCMAMRPDFRY
KFSYRIGNAS-KHTLYHGRDTQYYFVLPAGEPSDNYKVMVSTEITDGVGSRTLPCAVAVT
VLPHFHG-----SLCLDEDTYNSSLKHLSTLQLMGSYTKIRNYITTITR-VLSRWAAEDR
SP-SCGQWSRIQDALISSACGLPVADQEDMTHSVLMLRGLLRFPRKLSFRSAALILKSAR
APLAQS---PLSGRLAVDKGLMLELILLI-SEVLEASDWEKPRN-SGFLQEEGTKIISDL
LLDGLSASTEHQLHVSAGQMEFRTRLHHDLQSSVQSLGSVQVHLPADLA-AQSPVGA-VQ
GPCYISQLMLFKKNLYPWGQGPGQQIGQV-VSASLFGCSSRRPVGGWRLRAPVAVEFGE-
-EGGLDNGRTRTAFVLLRDRVNVHEFT-GA-ATPRESLHIRIEFFRPPSGAFPVMVLVR-
FSEKPTP-AFLVKKVYVWDEQPVHLHIPAGPLRD-------LSLGYLSLLDADYDRSPRN
RYSAKAVNYTVRFHWLQCVVWE-AGEWRPASSSPQPGVSPGKVNCSHDRLA-PVSISRRS
PNATFSASDISKLQRHPENLLPGVLIVVFTILYALLVTKSRRVDCHERKKAGYIFLQEDA
P-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2051)

YAVVVDTGFRSPTRCSAKVYI---VLCGEHGLSGPRELYCPEQ-PLFE-----
-RNSRHTFVLSVPALLGPLRRICLWHDSRGPAPAWYVSHIMVKELAAGPGHSWLFPAECW
LAASGRDGHT

ENSGT00700000104221_7_Linker_6_7 (2051, 2668)

AWELGSLRRGLGFWKLLYCKFTEYLEDFHVWTSVYSRPSPSGFLPTARLT
VAFALLCAYACLTALVTAAGQEQLAWALSAPDAASAGSLWTGLLGTLLASPGAQLLSLLF
RLSQDAGGP-SRVNACQ-SRSPLVG---AA-PKAAPE--------GPWARVGRATH---P
P-AEGSLVSG-SSGACRRAARGDGA-------G---------CPP-PE-REDLG-ADAAQ
RA--RR---EKGSPGAQAA--SSGFGGVAALRWPWALLPWSGSAAWVLCGTVSVACGLGT
AFLGYRFNPTQCVRWLYLLAASVLCCVLVTQPLLVSL-LALGFAWRRRHDPH--------
---FFTEALHAATKDL-GPELEARARPHP------------PHCASQKEEVLAARQRVRH
LRR--ARPPSAAQLSAVRQKLRRQTRTRRALR--DMCMFTLLLLLHLLILCRTGSRD-AH
SLHHAIRTEFTRGASSASGGLGSVADWWSWTLTTLLDGLHGGGAPPARPPGTQPRALGGT
CYLLGSLVIRQLRWPSGSAGQLPSRAPALPEDP----PPEV-GGPDGAPVTEPATPG---
--DS------RGCG----SR--EPWEL

PF08016 // ENSGT00700000104221_7_Domain_7 (2668, 2925)

SLGSTRP--AAHAALSGLRAGGWIDGGTSAVSV
HFVLYNCPTRLLSSVALHAELLPAGGLALAPLVESVAAFHSDSGLWHRL--------ALP
EQLAFLVLSLTQSCLQLHRAAQEGVHSYWGEPGSWLELAIAGAGLARYAASCHLATVAGA
VTDRLHRGHFRGSMDLSLAASWSQRVMWLQGTLSFLLTLKCVHLVSIRGTTASCSF---L
MRRSLA--SAFAAALAGVLALAAHSHL-RA--------VPP-GTLTDFSRG--PRS----
--------RL---SRSNLQAPAWCC--GALFMVMSTAWLGMLRGSFTTLAQR-RKSFQSQ
SVVRLADVTAYVRTEALAWLGLERPQQEEAEMVESHNY-YLD-DVSDLLDELLSKIHALS
DSLQLPLPEQQFC-----DMREARAK----------------------------------
-------------------

-----------PAEEAGRVTRCLQAACCLSFGSELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMNDGKCDCPRCALKRQAADRESQSPSSLPSGQKNIWKTTSKVALSVVN-
-------EKTQAPLDCDNSADRIPHKPSIIIVRAWSSCGPRFHHRRLCATGTTDSTFSGL
LQ-VQGTSSAAASCSLKMEASCCVLRLLCCAEDTAMGL----LPGTVTMETPTKVARPTQ
T--------VPLWPIS-----HFPTSTRSSHSLP--PSTPRTLSFMALQSGSEILYPPTQ
HPPVAILVQNSDNSMNPVLDCSLEMEARAPPNLGFRVHMASGEALCLMMDLGDSSGVEIR
LHNMSEAMAVTAYHQYSKGKVIF-FLLLHFQLDISTYKEAETK-----NMTLKVYLCQSE
NS---CQE---DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGIKVELGPYYVEIGREA
VSAFMNSSSVHEDEVLVFTDSQVNQKSTVVVHHFPPIPSYNVSFISQTQVGDSQAWHSMT
VWYRMQSVSVYTNGTVFATDTDITFTAITKETIPLEFEWYFGEDPPVRTTLRSIK---KR
LSIPQWYRVMVKASNRISSVVSEPHVIKVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTIRLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVCEPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYTWNLMDSEGLPVSLPAAVDTLRQ
TLILPSHTLEYGNYTVLAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDPD-----NPGATLRYHWECATASSPAHPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLYLVNATEKNKIEVPFCRVVGLLGSLGL-GAISKSS
QSNLLPTEP----------GTVDPD-ATTTPFSREPSLVTLGQPAPSTPR-----ETPTE
PVTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
THSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DAS-FPESGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAKPVLMIDWHKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTIFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYRGRDTQYYFVLPAGEHLDNYKVMVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIDSVLMLRDLVSFSNKLSLMSAVLIFKYTR
ALLAQG---QSSGPFVVDKGVRLELIGLI-SRIWEVSEQGNSKE-EGYLHEEGITVISDL
LLGCLPLN-----HISTGQMEFRTLFHYNLQSSVQSLGSLQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQATG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGPDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ASVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKAERFSPQPGTSPEKVNCSYNRLA-AFGLLRRK
LKASFEVSDISRLQRLYPGEEKEVFYYGFSDSLWILVAKSRQVDHHEEKKSGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYV---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTRLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-APAQSHC-LPRG--EAQAEAPQGPNS---------YQR-VSDAQEP---C
KHPASAIVSGSRRAQRKVAS--------------DDG---TACPA-PK-LEAHGGDHSRT
TLMGKS---HCCPPCTQAP--SSGLEGL-MSRWSRAPQPWWSSAVWAICGTASLACGLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----PFSSSCSIPDCAGEVEKVLAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISVDILMLLLLLGIMYGRFSQD-EY
SLNQAIRKEFARNGRNSFGGLRNITDWWDWSLTTLLDSLYPGGSPTTRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHLCKPPWPFSVPTEDSIPTCSPEG-GGPENPYLIDPENQNVTL
-NGA------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2901)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLVPSCLVESFSIFRSDSALQYHL--------VLL
Q-LVFLVLSLIHLCVQLYHMMDKGVFSYWQKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLFTLKCVYLPGIQNTMASCSS---M
TRHSLP--TIFVAVLAGALVLAALSHL-RRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRAMACYF--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKALTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLENTSN-----STGESRAEESPLVDIS-SKQATEVRPCKIIYVNFLYSNLSSK
GVLE---------------

---MA---EEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCGCPCCTLNGKAEDRESQSPSSSASRQKNIWKTTSEAALSVVNE
KTQAVVNEKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRWLCATGTADSTFSGL
LQ-LQGTTSAAAPCSLKMEASCCVLRLLCCVEDVATGL----LPGTVKMETPTKGARPTQ
TSS----QRVPLWPIS-----HFPTSPRSSHGLL--PGTPRSPSFTSSQSGSEILYPPTQ
HPPVAIPARNSDNSMNPVLDYSLEMEARAPPNLGFCVHMASGEALCLMMDFRDSSGVEMR
LHIMSEAMAVTAYHQYSKGKVFF-LLLLHFQLDISTYKEAETQ-----NITLKVYFCQSE
NS---CQE---DSDPTNLGYELVSAFVTKGIYMLKAVIYNEFHGTKVELGPYYVEIGHEA
MSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIT---KR
LSIPQWYRVMVKASSRISSVVSEPHVIRVQKKIVANRLT

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSAS

ENSGT00700000104221_7_Linker_1_2 (704, 751)

TLRKQLFVVCKPCQPPL
VKNMGPGKVQIWRSQPVRLGVTFQAAVFCD

PF02010 // ENSGT00700000104221_7_Domain_2 (751, 1407)

ISQGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTQSFHPD-----NPRATLRYHWECATASSPAHPCFDSSSAHQLDATAPTVS
FEARWLSASYDQFLVMLRVSSGGRNSSEARVFLSPYPDSAFRFV--HISWVSFRDTFVNW
NDELSLQAMCEDCGEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGL-GAISKSS
QLNLLPTEP----------GTADPD-ATTTPFSREPSPMTLGQPAPSAPR-----GTPTE
PMTGVYWIPAAGGSAVLG-----EAPEE-GSLDLEPGPHSKGSLMTGPS------ERSQP
THSPDPHLSDFEAYYSDIQEAI-PSGGRQPEK--DTS-FPGSGPSLSA--E-ESP--GDG
DNLVDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSS-GITEQTVTIKPYSLSSGETYVL
QASVASK--HGLLGKAQLYLTVNPAPRDMACQVQPHHGL--EAHTVFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDTQYYFVLPAGEHLDNYKVAVSTEITDGEGSKIQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIGSVFMLTDLVSFSNKLSFMSAVLILKYTR
ALLAQG---QFSGQFVVDKGVRLELISLI-SRVWEVSEQENSKE-EGYLHEEGITVISDL
LLGCLSLN-----HVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILSKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGK-
-EDGLDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ANVGYLSLLDADYDRKPPN
RYLAKAVNYTVHFQWIRCLFWDK-REWKSEHFSPQPGTSPEKVNCSYHRLA-AFTLLRRK
LKASFEVSEISKLQSHPENLLPSIFIMGSMILYGFLVARSRQVDHHEKKKAGYIFLQEAP
L-PGHQLYAVVIDTGFRAPARLTSKVYI---VLSGDNGLSETKELTCPEK-PLFE-----
-RNSRHTFILSSQSLLR---RSLLNS------QDFAL----LT-----------------
-----EMPHIREHFSCFP-----FQLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQHQLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGS-ARAEPHS-PLRG--GAQTEAPHGKCTLKLSETLRGAER-IPDAQEP---C
KHPASAVLSGSGRAQRNAAS--------------DDG---TACPA-PK-LEAHGADHNGT
ALMGKS---HCCPPRTQAP--SSGLEGL-RPQRSSAPQPWWSFAVWAICGTTSLACSLGT
GFLGYRFGQEQCVQWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLCEATRDL-DSELAERSWTCL----PFSSSCSIPDCAGEIEKVLAARQQARH
LRW--AHPPSKAQLRVTRERMRRESRTWAALR--DISMDILMLLLLLCVVYGRFSQD-EY
SLNQAIRKEFIRNARNSLGGLRNIADWWDWSLTTLLDGLYPGGTPSTRLPGAQPGALGGK
CYLIGSSVIRQLKVFPNHLCKLPRPFSALIEDSIPTCSPEV-GGPENPYLIDPENQNMTL
-NGP------GGCG----AK--EDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2902)

VLSLGRTRP--EAHTALSRLRASTWIDRSTRAVSV
HFTLYNPPTQLFTSVSLSVEILPTGSLIPSSLVESFSIFRSDSALQYHL--------MLP
Q-LVFLALSLIHLCVQLYRMMDKGVLSYWRKPSNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCQAFMDLTLMASWNQRARWLRGILLFLFILKCVYLPGIQNTMASCSS---M
THHSLP--SIFVAGLVGALMLAALSHL-HRFLL-SMWVLPP-GTFTDAFPG--LLFHFPR
RSQKDSLLGL---SKSDQRAMACYF--GILLIVSSTLCFGMLRGFLMTLPQKR-KSFQSK
SFVRLKDVTAYMWEKVLTFLRLKTPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKISN-----STGEARTEESPLVDIS-SYQATEDFTGKEI------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------ALPLAVIHDE-AHRTHQAGPSCVATGREA
VSTSTHAGSAHEGDVA---------FGPVVTHCSPSPASYDVAFTSQTHVGDSQARASRT
VWRPMQXXXXXXXXXXXXXXXDVTFVAVTKETWSLEFAWYFE-DAPVRTTSRSIR---RR
LAAPGRYRVVVQASGAKGSVASEPRCVWAQARVVPSRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 685)

VSTSSALVNTTVAFQCRINFGT
DVAFLWDFGDGTTGLGNSSASHIYSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXVQVRGSVVYANHCVSVEVRARAPVSVISEGTHLLVARR---
PSATVVLRGSLSYDP-----DRPRATLRYHWKCTPASSPGRPCFTGPSPRSLHVGAPTVS
FAADSLSRSYDQFLVTLVVSSDGRNSSEAQVFLSTRLDSALRFV--HVAWVRFRALPVNW
NDELSLRAACADCGDTAGLSYSWDLFVVNATEGSRAEVPFCRAVGLLGSARL-GATSQVS
ESARLSAGP----------SSTGPH-VTPTPSSRELWPQSPGWPDRSAAG-----TASAE
SVVTRHRVPAAGVTTAPG------DAPGEGS------------PGPSPP-----------
ERTPPSAAPDFEAYYSDIEEAA-PSGGRWPGT--SLR-LPGPGPSAS---ADGSL--GDG
DNLVGPVLPTAGARPALLVDWPKALVARAVFRGYTMS-GITGQTVTIKPYSLSPGETYVL
QASVASN--HSFLGKAQLYLTVNRAPRDVACQVQPHQGL--EAHTTFGVFCTSGAQDLRY
EFSYQAGSAP-QRILYRGRDTQRYFTLPAGEPVDGFRXXXXXXXXXXXXXXXXXXXXXXX
XXX-----XXXXXXXXXXXXYNSTLRNLSTLQLTGSHTEARDYVAVVAR-VLSRWAQEDG
SP-ACAWWSPVQDTLIASVCGLAFHDQXXXXXXXXXXXXXXXXXXXLSFASARLILEFAR
TLLAPG---LRAGGFVTDSGRMRELLLLL-SGLLGATAREPSRD-LDRLREEGVKAISDV
LL------------VGAGQAAFHARLHLDHRSAELRLGPVRVHLPAGLA-GQGPAGPETQ
RPCWVSQLLLFGRGLYPAARAPGQXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXYDRLA-AFAVARRS
LNPSFEASDVSAFQRQPENLLPSIVIAVFTILYALSVTKSRRVDRHEKEKTGYVFLQEDT
G-PGH

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2056)

QLYAVVVDTGFRSPAHCSAKVYM---VLCGENGRSGPRELHCPDR-ALFQ-----
-RNSRTTFILSTPAPLGPLRKIRLWHDSRGPSPAWYVSRVMVGELLAGPGRSWLFPAECW
LAADRQDGRVARELA

ENSGT00700000104221_7_Linker_6_7 (2056, 2678)

CLRQGLGFWKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXXXXX-XXXXXXX---XX-X--XXX--------XXXXXXXXXXX---X
X-XXXXXXXXXXX----XXXXXXXX-----------X---XXXXX-XXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXP--GGGSEGRAAPWWPRVPLPWLGSVAWAVCGTVSVACGLGT
GLLGYRFSQTQCVQWLCLLTLSVACCVLVTQPLMIGL-AALGFAWERKDDEH--------
---FFAASLHEATKAL-GAELEGLSRPRR----PRSASCDVPELEEXXXXXXXXXXXXXX
X------XXXXXXXXXXXXXXXXXXXXXXXXX--DACAYALMLMVHLMIVHGRFSQD-ER
ALSHAVRDAFTRRAGSAPGGRGGVDGWWRWSRSTLLDGLFRGS-VPAGLPGAQXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
-XXX------XXXX----XX--XXXXXXXXXXXS--T

PF08016 // ENSGT00700000104221_7_Domain_7 (2678, 2725)

ALAALTQLRARRWIDRGTRAVSV
HFALYNPPTRLLASVSVRAEMRPTGDLALSSLVESVVVFHGDSVWGQLL--------TLL
E-LAFLVLALVRLCSHLCGMAEKGVRGRWRKPGTWLELSVTGMGLACCAASSH-GTLAGE
V-TQFHKGFFXXXXXXXXXXXXXXGTRRLQGALSVLLTLKCAHLLGTRAAVAPCSF---V
TRHALP--GILASGLAGTLLLAAQAHL-RSLLL-CSPAPAS-GTFADAFPR--LLPRLPG
GGHGGALPGP---SEAGGRTAALLC--VTLLAGVSALWSGMLRGSFMTFARK-RKPFQSQ
SLVQLRDAAACVWGTACT-----RPGQEGTEAREGHHP-CLD-EFACLLDELLLKVTGCS
DSPRSPRPESGLGGARPEDQPSARASADPATG----------------------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------SADVF---PGAHHSQGLSVTQPGPRKPCLLSL
CLPWAIATQGPAVVENSVTQQLPETDTWASPYLGFKVQMASEGPLCLVTDFGDSPGVQMK
IQNTSEEITVTAYHQYRKE-----------------------------------------
-----------------------------GVCMLKAVIYNEFSGTEVELEPYYVEIGHEV
VSVFMNSSSVHEGEVLIFARSHIDQKSTVVMHHFPFTSSCNVS-TSQSQVGDSQAWPSVI
VWYKMQPVS

PF00801 // ENSGT00700000104221_7_Domain_0 (550, 629)

VYTNGTVFATDADITFVAVTKEMSPLEFEWHFGEDPLVRTTSRSIK---KR
LGIPQRYDVVVKASNGITSVVSEPHPIT

ENSGT00700000104221_7_Linker_0_1 (629, 639)

VQKKIVANRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 711)

LSTSSALLNTSVTFECRINFGT
DVAYLWNFGDGTVSLGNSTNTHVYSREGAFTVEVLAFNNVSSALLRKQVFIVHTPCQPPP
VKNMGPTKLQVWRSQPVRLAVTFEAAILCDISQGLSYTWSFMKSNGSHVSLPPAVDNHRQ
TITLPSYFLEYGNYTAVAKVQVKGSVVHSNYSVGVDVRDRAPVSVISEGTHLFIPKT---
PSSTIILSGSQSYDP-----DNPGAPLRYHWRCAPAGAPECPCFHAPMPGGLDTTAPVIS
FAATDLSDGFDQFLVTLKVSSGSRTSPEAQVFLSVRSEQTLRFV--HISRVNFKNNFVNW
NEELSLQAVCEDCGDIQNLSYSWDLFLVNATEQNSVEAPLCRVVELLDSSRF-GAILKLS
ESTQLLVEP----------NTTDPG-LTTMSFSQEPLQKTIGQSAPSAMR-----RPSKK
PTVGVYQVFAVDADASGQ-----EDAPREAALSPEPGLLEEGSLV-TSLWKGEWRSGNLR
PQNLSSYLSDFEAYYDDIQEAI-PSKGRQPGN--NMN-FLGSEPSGS---DDKSP--SDG
DNLVGPFHSMGSAMPSLMVDWPKSLIRQAIFQGYTSSVGVIEQTVTIKPFSLRRGETYVI
QASVASK--HTLVGKAQLYLTVNRGPQDIACQVQPHHGH--EAHTIFSVFCMSGKPDFRY
EFSYQIGNAS-KRTLYHGRDAQYYFALPAGEPLDNYRVVVFTEITDGEGSKLQPCAVVVT
VLPRYHGNVASGNYCLGEDLYNSSLKNLSTLLLMGSYLEIRNYITMITR-ILSFLAKEDR
GP-SCGQWSRIQDALISSVCKLEFTDQEEITDSVVMLGDLLSFPNKLTFMSAVLILKYTR
SLLAQS---RLSGRFVIDRRLMLELIFLV-SGVLEASDQEKSRN-ADYLQEEGIKVISDL
LL----------LHVGTGMMEFQVWLHYSLQDTVQSIGSVQVHLPSDLA-GQSPAGTDLQ
NPCYISQLILFKKNPYLKGRAPG-QVDGA-VALSLYDCSSRQPFSRHWLQTPVTVEFGE-
-EDSLDSRRNNTTFVLSRDKTNFHQFI-GPSENSQESLQIRITFSKTITRAFPIMLLVR-
FSKKPTPSDFLVKQVYFWDEQVVQIYIPAVSLED-------ASLGYLALLDADYDRTPSN
KYLAKAVNYTVGFQWIRCLFWD-KREWKSSTFPPQPGTFPEKVNCSYDHLT-AFTLVRRK
LNVSFEMSDISNLQSHPENLIPSVIIVLFMILYMFLVAKSKHVDHHEKKKTGYIFLQENP
S-PDQ

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2054)

QLYAVVIDTGFRAPAQLTAKVYI---VLYGENGLSETRELYCPEK-PLFE-----
-RNSRHTFILSVPGHLGPLWKIRLWHNNCGPSPSWYISHVLVKELRTG--QSWFFSAECW
LAAGRGDGRVDRE

ENSGT00700000104221_7_Linker_6_7 (2054, 2535)

LIPLHRGLGFQKLLYAKFTEYLEDVHIWVSVYTRPSYSCYLHAQRLS
VCFSLLCAYSCLTAMLTAAQHRQLSLDVNLTHI-TPGSFRSGLLCTLVASPGALLLSLLF
RLSQNTTGL-CREKPSC-RLRAVPG---EVTR-AGPN--------SHGRTLGAQKK---Y
KCNTSDILRGKDR-----GWRADP---------ASGG---ALCGD-LPVSFPL---RKSV
TTMEKE---GKSPTSSSAP--SSGLAGLA-PQQQRALLPWLGSAAWALCAMVSVACGLGT
GVLGYSCVPKCCISAVGVRFLSMFSCDLRAHLLKVCH-HIQASPWSRVRLQKKYCANAKD
NCSHYFDSIRHTSHAQ----L-------Q----SLPKKCS-WDRSRLLKQVLANRQQARH
LRW--ARPPSTAQLRATKERMRKEIRARAALR--DFFMYILMLLLLMFMTYGRFSRD-EY
TLNQAIRNEFTRNA

PF08016 // ENSGT00700000104221_7_Domain_7 (2535, 2992)

ENSFKGLRSTDSWWEWSLTRLLDGLYG-----ADVHGAQPGALEGK
CYLTGISVIKQLNISLNSLCKLSSPFSALIKDALPACSPKV-GGPINHYMTDPENQKVTP
-SRP------EGCG----AR--EDCVLPLGRTRP--EAHAILTNLRANRWISRGTRAVSV
HFTLYNPPTQLLTRVSLRMEVTPTGHLLPSSQVESASVFLSDSTLRYPL--------VFT
E-LVFLVLNLVHLCFQLYSMIEKGILNYWRKPSNWLELSVVGLGLAYYAASSHLVILAGD
VIDQFHKGFFQEFVDLSLITSWNQKVRWLQGILLLFLILKSVYLLGTPKTMASCSF---M
LRHSLS--NAIMPGLAGVLMVAIHSHL-CRFLL-SSQALPL-SIFADSSHM--LPFPLLG
RSRREAFSGL---SKSNQWATACYH--GAIFTVMTTLWLTMLRGSFMAFVRK-RKYFQSK
YLVRLKDVAAHTWGQAVTFLGLQRPRLEETQVVENHNY-YLD-EFEELLDELLLKINGLS
ENLHLPLLEKQSD-----STVEAKAEDNPLVGVS-GYQATGVS-----------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---FQCNYSAVVLYSLKMENSGCIIKLLCPTENVVKKL----APGTVKAGACIEAVGPVQ
DSTK--HPALLLWPTSYFLAFLR----STGESP---PCAYHAPGLSATQPGFRNAYFLTT
HPTEAIPTGGPTVVVTPVTQCFPATDTWTTPVLGLRVQMASEGSVFLGIDFGDDSGVQMR
IQNVSGEISATACHQYREXXXXXXXXXX----XX-XXXXXXXXXXXXXXXXXXX------
----XXXXXXXXXXXXXXXXXXXXXXXXXXAVTLKAVLYNESYGTEAELGPYYLEIGCES
ASVFLNSSSVHENEVILFADSHTDQKSTVIMHHFPPLSSYNVSFMCQKPAGDNQAWPGVT
VRYKMQPVS

PF00801 // ENSGT00700000104221_7_Domain_0 (550, 629)

IYTNGTVFATDVDITFVAVTKETSPLEFEWHFGEDPPVRTTSRSIG---KR
LRMPQWYHVVVKASNGITSVVSEPHSIN

ENSGT00700000104221_7_Linker_0_1 (629, 639)

IQKKIIANRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 711)

SSISSALVNASVTFECRINFGT
DVAYLWNFGDGTISPGNSTQTHSYTREGEFSVVVLAFNDVSSASLRKQLF

ENSGT00700000104221_7_Linker_1_3 (711, 769)

IVRTPCQPPP
VKNMGPEQVQVWRSQPVRLGVTFEAAILCDISQGLSYTWSFMRSDGSH

PF02010 // ENSGT00700000104221_7_Domain_3 (769, 873)

VSLPSAVDNHKQ
TIVLPSYALDYGNYTAVAKVQVEGSVVYSNYSVGVDVRARAPVSVISEGTHLFISRT---
PSSTIVLSGSQSYDP-----DDQGTPLRYHWKCAPAVAPSRSCFHAPAPGGLNTTAPIIS
FSAMDLSASYDQFLVTLMVSSSNRTSSVSQVFLSLHSEPASRFI--HLSQVNFKNNFVNW
NEELSLRAVCERCDDMYNLSYSWDLFLVNATEQTSLEVPFCRAVELLDSSRL-GTIMNLS
KSNPQLVKP----------NPRDPG-VTIGPFSWEHPQMTIGQSASSAMV-----RTLRR
PRSIGPRVAAVVEASGQ------EDDIGEAELSQDAEFLEEGSPV-TSPWETKHPSGSSL
PQNISFYLSDFEAYYGDIQEAV-PSSGRQPGT--NMN-FPESEPSQS---DDQNP--EDG
DNLLDPFHSMGSAIPLLMIDWPKSLISRAIFQGYTSTXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX-XXXX--XXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXEEIIDSVLMLRDLISFPNELTFRSGSLIIKYMW
ALLARS---QLLERFVTDRELMLKLIGLV-SGVWQVSEQEKSRT-VDYLREEGIKVISHL
LLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX----
XXXXXXXXXXXXXXXXXXXXXXX-XXXXX-XXXXXXXX-XXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
SSKKPTPSDFLVKQMYLWDEKIIQIYIPAVLLKD-------STSGYLALLDASYDRPSSN
KYLASTVNYTVDF

PF01825 // ENSGT00700000104221_7_Domain_5 (1814, 1861)

QWLQCLFWD-KRRWKSNTLPPQPGTSPDKVNCSYDHLT-AFTLARRK
LNASFEMSDISTLQRHPENLIPSVFIVLFMILYAFLVTKSMHTDHHERKKSGYIFLQGSS
S-PDQQLYAVVIDTGFRAPSQLTAKVYI---VLYGETGLSETRELSCPEK-PLFE-----
-RNSRHTFILXXXXXXXXXXXXXXXXXXRGPSP-WYISHLLVQA-RWGTGQSWFFPAECF
LAAGHGDGKVERELIPLHQGPGFWKLLYAKFTEFLEDFHIWISVYSRPSYSCYLHTQRLT
ISFSLLCMYSCLTAALTAA-QEQLSLDVSPTHI-TSGSFRTSLLCTLVAFPGALLLSLLF
RLSQTNAGP-SRESPAG-A---VSG---EA--TRGPN--------SHGRTLDAQKS---Y
KCNTLDVFSRHNSDRRMAAS----------------RR--RLCSP---------------
-------------LHTHAP--SGGLAA-PAPQWQQMLSPWLSFAGWVLCTFVSIACCLGT
GILGYXXXXXXXXXXXXXXXXXXXXXXXXXXPMALCL-RALGFAWKRKDDKA--------
---FFTESLCDATKEL-ASELEHLSQTCV----PLSASCGVPDCASEFEKILATRQHTRH
LRW--ACPPSIAQLRTTKERMRKEAYAQTVLX--XXXXXXXXXXXXXXXXXXXXXXX-XX
XXXXXXXXXXXXNIENSFGGLKRFDDWWEWSLTKLLDGLYGD-----NMQRAQTGALGGK
CYLIGTVVIKQLNSPPNNFCKLPKSFSAPIKAAPPACSLKV-GGLVNFYGTDPGYQNATI
-SPP------TDGK----TR--ENA

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2737)

ALRLGKTRS--EVHTALINLRAKQWIGKDTKAVSV
HFTFFNPPTQLLTSVSLRAEVLPAGSFLFSSQVESVRIFLSDSATRYLL--------LLP
EXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X
XXXXXX--XXXXXXXXXXXXXXXXXXX-XXXXX-XXX-XXX-XXXXXXXXX--XXXXXXX
XXXXXXXXXX---XXXXXXXXXXXX--XXXXXXXXXXXXXXLRVSLMNLTRK-RNSFQNK
YIVRLKDVTAYTWEKVLVFLGLERPRPEETQGDEHHTY-YLD-EFEDLLDVLLLKIDDLS
NSLHIPALETHTS-----RTREARADESPAVGIP-DSQAAQ-------------------
-------------------

---MPDPHRLEERALRAASEQCLQAACCLSFCGDMPVSTDKSWGLHLYSCS--PPGGGVW
VE-VCANRVLLMSDEKCGCPRCALNRKAEDGESQSPSLLASGEKNIWKTTSKAVSSV---
-----VNEKTWVPLDCDNSANSFPHKPFVIIASVRSSSGPSFHHRRLCATGTTGSASSGC
LQ-VQGTSSAATPCSLKMEASCCVLRLLCCAEDVASGL----LPGTVTMETPTKAARPIQ
T--------IPLWPLSHFPTSPR-----SSHDLP--PGTPHTPSLIASQPGPESFCPPTQ
RPPVAILAQNPDNSINPIIDCFLEMETWAPPNLGFHVHMASGKAICLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVHSV------------------------------------
-------------------------LIRKGVYMLKAVIYNEFHGTEVELALLLESAIEAI
HMIFKNSDALMKDRISI-----PLDLCTVVIHHFPSIPSYNVSFISPSQVGDSQAWHSMT
VWYKMQSVSVYTNGTVFATDTDIAFAAITKETIPLEFEWYFGGDPTVRTTSRSIK---KR
LSIPQWYRVMVKASNRISSVVSEPYVIRV--------------------VVFECRINF

PF00801 // ENSGT00700000104221_7_Domain_1 (659, 703)

GT
DVAYLWDFGMAPSAWGAAPAAMSYSREGEFTVEVLAFNNISASILRKQLFIVCKPCQPPL
VKNMGPGKIQIRRSQPVRLGVTFEAAVFCDISQGLSYTWKLVDSDGLPVSLPASVDTHRQ
TLLLPSHTLEYGNYTALAKVSS------LTYCSTSPVKPMLPITLEQELS--------IC
NSTPQVLAGESRVKL-------------------CGGRPGCQCQNRDPQVKVSAAKELCS
FK-LW-----AQFQL---------------VPYISNQDICFRFL--HISWVSFKDTFVNW
NDELSLQAICEDCGEMPNLSYSWDLFLVNATDKNRIEVPFCRVVGLLDSLGL-GAVSISS
QSNLLSTES----------GTADPD-ATTTPFSREPSPMPLGQPAPSAPR-----GTPTD
PMTGVYWIPAVGDSAVPG-----KAPEE-GLLDPEPGPQSKGSLMTDPS------ERSQP
TLSPDPHLSDFEAYYSDIQEAI-PSEGRQPAN--DTS-FPGSGPSLSA--K-ESP--GDG
DNLMDPSLSAGRAKPVLMIDWPKALLGRAVFQGYSSS-GVNAL---FRPCNCSVSEAVRS
QPSISSE--LFILLDKYLELW--------VCV--------------CVCVCVCVYWDVI-
-----------HMFIYTIFYTQYYFVLPAGERLDNYKGTVSTEITDGEGSKVQPCTVVVT
VLPRYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSQTQDALISSVCKLAFVDQVCIYASYTMKHFIYI------FSLAVLILKYTR
ALLAQG---QFSGPFVVEKGVRLELIGLI-SRVWEVSEQENSKD-EGYLREEGITVISDL
LLGCLSLN-----PVSTGQMEFRTLLHHNLQSSVQSLGSVQVHLPGDLA-GQSPAGVETQ
SPCYISQLMLFKKNPYPGGQVPG-QIGGV-VGLSLYNCSSRRPINRQWLRKPMMVEFGE-
-EEGLDNRRNKTTFVLLRDKVNLHQFT-ELSENPQESLQIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKD-------ANVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKSERFSPQPGTSPEKVNCSYDHVA-AFALLRRK
LKASFEVSAFPSSR-------------------------------GKKLASQYIYYGKLP
C-RRHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2042)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGRSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKICLWHDSCGPSPSWFISHVMVKELHTG--WGWFFPAQCW
L

ENSGT00700000104221_7_Linker_6_7 (2042, 2665)

CAGRRDGRVERELTCLRGGLGFWKVAWHLIFL---------------------------
AFASVLCSYSI-RAVLSAVGLLQPQLDVSP----SLESFRMGLLCTLLASPGAQLLSLLF
RLSKEAPGP-VRVEPHS-PLRG--GAQTEAPQGSNS---------CRR-ISDAQET---C
KHPASAILSGSGRAQRKAAS--------------DNG---TACPA-PE-LEAHGADHSGT
ALTGKS---HCCPPHAQAP--SGGLERL-MPRWSRAPLPWWNSAVWAICGTTSLACGLGT
GFLGYRFGQEQCVQWLQLLSLSVVCCVFITQPLMVRN-TLHGEGMC--------------
---IRDRSLFEATRNL-DSELAERSWSCL----PLSSSDSIPDCAGEVEKVLAARQRARH
LRW--ARPPSKAQLRVTREGMRRESRTRAALR--DISMDILMLLLLLCIIYARFSQD-EY
SLNQAIRKEFTRNARNSLGGLRNITDWWDWSLTTLLDGLYPGGSPSTRVPGAQPGALGGK
CYLIGSSIIKQLKVFPNHLCKAPRPFSVLIEDSLPTCSPEV-GGLEKPCLIDPENQNVTL
-NGP------GGCG----AR--ED

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2895)

YVLSLGRTRP--EAHTALSRLRANTWIDRSTRVVSV
HFTLYNPPTRLFTSVSLSVEILPTGSLIPSSRVESFSIFRSNSALQCHL--------VLP
Q-LVFLVLSLIHLYIQLHRMLDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLATLAGD
VTDQFHRGLCHAFMDLTLMASWNQRARWLQGILLFLLTLKCIYLPGIQNTMASCSS---M
MRHSLP--SVFVAGLAGAPMLAAISHL-HRFLL-SMWAPPP-DTFTDAFPR--LLFRFPG
RSRKDSFLSL---SKSEQQAMACYF--GALLIVSATLCFGMLRGFLMTLPRKR-QSFQSK
SVVRLKDVTAYMWEKALTFLRLKAPKLEEAEMIENHNY-YLD-EFADLLDELLMKINDLS
DSLQLPLLEKTSN-----STGEARAEESPLVDIS-SYQATEVRPCKIIYVNFLYSNFSSK
GVFEYLLF-----------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------AGCWSSGGPGCHHRAMCAVGGLDGAFCEL
---VQCAC-PAGPCSLKVEVPSCAVGPLRSAEDLAPEL----LPRTDATTGVPIQ-AAAS
AQTSIPTSQPAVWPRRSEVVPSP----HSPHGLPPGPPCTLSL--STPRPGHQQLRPHAQ
CPAAAFPALGPEDAADPVAPRFPQADAQALPSLRFRVQITPEAALCLVMDFGDGSGVQMR
THRATGDVTVTTFHRYRRGMCSGSRGCV----IR-CEAKKHGATLSPAVMVLQS-ISTGR
F---TEVSSCPAVGGQ---HLFSFLRLFHGVYALQVVLYSESHGAEVRLGPYYVELGPEA
TSVFLNASSVLRGHMCAFGGSPTDPRSTTVSHRFPPTSSCNVSFALQTHVGGRRAWSSMA
VRYRMQPVSVYTNGTVFATDTDITFVAVTKETIPLEFTWFFGEDLPVRTRRRSIQ---RR
LGAPQWYRVVVQASNGMGSVASEPHRVQAQRRVVASGL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 711)

VAADSALVNAPVTFQCRVSFGT
DVAYRWDFGDGTGGRGNSSASHVYSREGEFTVEVVAFNAVSAVSLRKRLFIVRRPCQPPP
VKNMGPGQVQVWRAQPVTLGVTFEAAILCDISQGLSYSWSLTNSAGSPVPLPPAISTHRQ
TFTVPHYFLEPGNYTALAQVQVRGSPVHSNYCVGVEVCARAPVSVISEGTHLFIPRT---
PLSTMVLRGSLSYDP-----DRPGATLRYHWACTPASAPGRPCFTGPSAHSPDAGAPTLS
FAADSLSSGYDQFLVTLTVSSHGRNSSKAQVFLSTLPDVALRRV--HISWETFRGVPVNW
NEELSLRAACEDCGEA-ALSYSWDLFLVNATGRDREEVPFCRTVGLLGSSGL-GSVSKLP
ESDPWSLGP----------RRAEPH-VTPVQFAQKPWPWTLAQADLSATG-----RASAE
STVPTPQVPAAGDPVAPE------GDPWDE-GS--PGSPTPHPPVSDGTRESQL---SQA
LPTPPPHPADFEAYYSDVQEAV-PSRGRQPAAWTSMH-LSASGPGAS---EDGSR--GDG
DNLVGPFLPTASARPALLVDWPKSPVSRAVFQGHTTS-GITGQTVTVKPYSLRPGETYVL
QAAVASG--HSFLGKAQLYVTVNQAPRDVACQVQPHRGL--EADTVFSVFCMLGRPDFRY
EFGYQIGNAS-KYTLYRGTDAQHYFALPAGEPMDGYRVLVSTVITDGDGSQTQPCAVAVT
VLPRLQG-----DRCPGEDVYNASLRSLSTLQQMGSDTEVRNYVAVTTG-VLSRWAREGG
SP-SCGQWSRIQDAFISSICRLAPRDQEEAADSVLLLRDLLRFPNKMSLASALLILDCAH
TLLAPS---RPPAGCAVEAGQVRELILLV-SGVLEASDHGHSRS-SGRLLEEGAQAIADV
LLGCLSSRGEHRVHVSAGQTEAQAQLYRHPQSSEQSLGPIQVRLPADLA-GREP------
SPCYASQLLLFRRSPFLQGRVPG-QVGAL-LALSLHRCSSRRPLHRPRLRTPVTAEFGE-
-EDGPGDRRNETTFVLLRDRVNVHHFT-GLSAASPEALQIRVEFSQPAARAFPVMLLVR-
FSEKPTPADFLLRQLHLWEGLTAHVSVPAAALEG-------HTQGYLSLLDADYDREPPN
RYLAETVSYVVRFQGVHCLLWD-PRR-EPESLPPQPAASPGKVNCSYDLLA-AYSIARRS
LNASFESRDVAQFRGRPENLLPSIFIVAITILYALLVTKSKRMDRREKKKMGYIFLQDSA
P-PSH

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2056)

QLYAVVVDTGFRAPAHFTAKVYI---VLCGEDGLSEPRELCCPEK-PLFE-----
-RNSRHTFVLSTPAALGPLRKVRLWHDSGGACPAWYVSHVMVKELRQGRG-RWFFPAECW
LAAGRWDGRVERELA

ENSGT00700000104221_7_Linker_6_7 (2056, 2535)

CLRGGLGFRKLLFSRFTEQLEDLHVWASVHSRPAGRGLLHTPRLS
VAFALLCAYACLAALVTTAGHGQLPPSVGPAGV-PLGSFWTGFLCTLLASPGAQLLSLLF
RLSQQAQGG-KGVRSHE-YIWVLWG---TEAPGPVQG--------EGWGGVGSFKE---P
R-SAPAVLCG--------GAQAQSA-------ASGDG---ATQPP-PE-LEACG-AELGQ
WALREK---RDCILGLQAP--SRAFEGHVTTPWPRAPRPWLRSAAWAICGMVSVACGVGT
VFLGYRFGPTQCGQWLCLLTISVTCCVFVTQPFMVGL-VALGFAWKRRDDES--------
---FFTESLREATEGL-GTGLAGLSCTRT----PHSPCCSRPRGPGVVERVLAERQRARR
LRR--AHPPSTAWLRATREKMRRQTRTRAVLR--DTCMSVLMLLLHLLITHAPSTRD-EH
SLNHAIRNTFARGA

PF08016 // ENSGT00700000104221_7_Domain_7 (2535, 2992)

RSSSGSLSSVDAWWDWSLTTLLDGVY-----PVGVPGAQPGALGGT
CYLIGPAVLKQIRLSPGPSCELPRPLSMLPEDSLPTCHPKV-GGSETPSVTNAETQRVAP
-SDP------TAC------R--EHCELSLGRTRP--AARAVLTGLRARRWVDHRTKAVSV
HFVLYNPPTRLFSSVSLRAALLPAGGLTLSPLVESVTVFHSDSAPRYHL--------LLP
Q-LAFLALTLTHLCLQLFRLAEEGVRGYWQKPGAWLELPLAGAGLAWYAASGHLLSLAGE
VTEQLHMGLLRGFVDLSLLCSLPQRARWLQGTLSFLLTLKCLRLLGSHSAVASCIF---A
TRRSLA--GVLAPGLAGVLVLAAHAHL-RGISL-LTVAPPS-GTFADAS------HRFPG
SSQRDTFPGL---SKAEQAT-AGRC--TALLAAVTTLWVGMLRGSLMAFVPK-RKSFQSQ
SLVRLGDVMAYVWGAACSALGLERRPPEEAEPATRHNP-SLD-EFADLLDELLLKIDSLS
ARLPVPLPVQPPR-----DAPQAGAGAEGSPSLG-ASDDQAARPSGIEKP----------
-------------------

------------------------------------------------------------
----------------------------------------------------NILKPTSK
AMLSFVNGRTSAPPDWGNCANRTSPTLSITIGIISSSSGPTSLCQPMCAIEKVSITFFDL
L-EFQCNPSARAPYSLKMEISSCIIKSLRSTEDVVKKL----SPGTIEMGACTEAVSPIQ
VS----SKQSLLWSTSLFLTFPR----SSTDVP---PGICYSQGISATPSGPRKLCLLSS
CLPGAITTEGPAVSVNPVTQWLTKTDTWMSQDLGFKVHIASEGSLCLVMDLEDKSGVQME
IRSMSEEIIVTACHHYRKXXXXXXXXXX----XX-XXXXXXXXXXXXXXXXXXXXXXXXX
X---XXXXXXXXXXXX---XXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXVSVYTNGSVFATDADITFVAVTKEMSALVFEWHFGKESPVRTTSRSIV---KR
LRIPQWYHVVVQASNGITSVVSEPHPISVQKKIVANRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 711)

LSTSSALVNTSVAFECRINFGT
DVAYLWNFGDGVVSLGSNTNTHVYSREGEFTVKVLAFNNVSSALLRKQLFIVYTPCQPPP
VKNMGPRKIQVWRSQPVRLGVTFEAAILCDISQGLSYAWSFMKSNGNHVSLPPAVDSYRQ
TITLPSYFLEYGNYTAVAKVQIKGTVVHSNYSVGVNVQARAPVSVVSEGTHLFIPKT---
RSSTIVLSGSQSYDP-----DNPGMRLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLDSSRF-GATLKLL
ESTPLLMEP----------NTTDSG-SVTMPFSQEPLRKTVGQSTPSAMG-----RPSQE
TRMSIYQVFAADADASGQ-----EDAPGKAALPAEPELLEEGSAVTS-PWEG-----DRP
THRNCPHITDFEAYYEDVQEAI-PSKGRQPGN--NIN-FPGSEPSGN---YHKDP--SDG
DNLVGPFHFPGSAVPSLLVDWPKSLISRTIFQDYTSSXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX--XXX-XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXDFHY
EFSYQIGNTF-KRTLYHGRDAQYYFALPAGEPLDSYRVIVFTEITDGEGSKSQPCAVAVT
VLPRYHGNIVSANYCLGEDLYNSSLKNLSTLLLMKSYTEIRNYIAMIIR-ILSCLAKEDR
VP-SCGQWSKIQDALISSVCKLEFTDQEEVTGSVI-LSDLLSLTNKXXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXSSLSVSSEPQLHVRTREMEFRASLHYSLQNTIQSIGSVQVHLPGDLG-GQSPAGTDGQ
NPCYISQLIFFKKNPYRRGQASGQXXXXX-X-XXXXXXXXXXXXXXXXXXTPVTVEFQE-
-EDDINNRRNN-TFLLNQDKMNFHQFV-GLSENSQESLQIRIKFSKTITKAFPVMLLVXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXX

PF01477 // ENSGT00700000104221_7_Domain_6 (1931, 2053)

XXXXXXXXXXXXXXXVYI---VLYGENGLSETKELYTSEK-PLFE-----
-RNSRHTFILSVAGHLGPLWKIRLWHNNSGPSPSWYISHVLVKQLHTG--QSWFFSAECW
LAAGRGDGKVER

ENSGT00700000104221_7_Linker_6_7 (2053, 2535)

ELIPLHQGLGFRKLLYTKFTEYLEDVHIWGSVYSRPSYSGYLHTPRLT
VCFSLLSVYSCLTSVLTAV-HQQLSFDVGLIHI-TPSNFKTGLLCTFVGSPGALLLSLLF
RLSQDTKGP-SREDPSC-RLRAVSG---ELTQDCSSG-----------RSLGAQKK---T
---TSDICPENNGGRAHPHWDKLRE----------KGD--SSSPTQXXXXXXXX-XXXXX
XX--XX---X---XXXXXX--X--XXX------------X-X--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX--------
---XXXXXXXXXXXXX-XXXXXXXXXXXX--------XX--XXXXXXXXXXXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX--DFSMYIFMLLLLMFITYGKFSRD-EC
AVNKAIRNEFIRNA

PF08016 // ENSGT00700000104221_7_Domain_7 (2535, 2989)

EDSFEALRNTDDWWDWSLTRLLDTLYGA-----DTQGVQPGALGGK
YYLIGISVTKQLNSSPNSLCKLPSPFSAPIKDSLLACNPKV-GRPVNHSVRGPENQKMAP
-SRP------EGCG----ER--EDCALRLGRKRP--EAHAALTNLKATQWIGQGTRAVSV
HFTLYSPPTQLLTSVSLRAEVTPTGLIHPSLHVESANVFLSDVALRYPL--------MVT
E-LVFLVLNLVHLCFQFYSMIEKGILNYWQKPSNWLQVSVIGLSFAYYIASSNLVILDGN
VVDRFHKGLFQEFMDLSLITSWNQRTQWLQGTLLLLVILKTVYLAGSPKMMASGSF---M
LRCSLS--SIVTSGIAGVLMLAIHSHV-ERF-LFSSQALSL-STYTDSSHL--MPFPFLG
RRREEAFSVP---SNSNQWGMACYH--GAIFAAMTVLWLAMLRGAFMAFAR---KPFQSK
YVVRLTDVTAHAWGKVLAFLGLERPKVEDTQVVVNHNYYYLD-EFSELLDELLLRINGLS
DSLHLPVVEKQSD-----SMVVAKPEDSLLVGVF-GYATELS---DLEL-----------
-------------------

------LATVVAEGLSDDGEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXSPHPSPVPITSTWSKGGLGSCRRQPCAAGNEAGGYFSG
LLKQGTAC-EEAHCGPNVTASCLAPGGQSPVGDIAKGT---PVAGFGSTIGV--SG----
-------AQTCXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----X--XXXXX--------XXXXX---X--
----XXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXAGVTHRLPFASAYSVSFVSWARTGGCLAWHSIP
VGYRI

PF00801 // ENSGT00700000104221_7_Domain_0 (546, 628)

ASVSVHTNGTVFATDMEVTFEAVTTEPTPLEFMWLFGNDPPVRTASRSIK---RR
LRKPQGYQVTVEASSRFGSVVSEAHLI

ENSGT00700000104221_7_Linker_0_1 (628, 639)

KVQERIVANRL

PF00801 // ENSGT00700000104221_7_Domain_1 (639, 684)

LSTTSALVNTSVAFECRISFGT
EVSYHWDFGDGTVSLGSSSCSHVYHXXXXXXXXXXXXXXXXXXXXXXQLFIVRH-CS--P
PKNLGPPKVQVWRSQPLRLGVTFEAAVLCDISRGLAYTWIFLDAEGSRVRLPAAVDTHRQ
TIELPGYTLLSGNYTALAKVQIQGSVVYSNYCVGVEVRPRAPVSVIAEGTHLFVPRA---
ASAPLVLRGSQSYDP-----DHPGAVLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFV--HLSWVSFKASAVNQ
NTELSLQAACEGCGDLQDLTFSWELFLVNATEDRRLAVPACSAVGMLGVSAL-GASWESS
EPSSLSTEP----------SAAGPDSGTSVHLPWAPSPLPQGPPALSATW-----STSLE
STAGTHQTPAAV----PG-----ED-LDEGPLGLEVDSWDGGIPTRSPD-ER--------
-SWSSP-YPDFEAYYRDIEEAE-PSRGRQPAG--SAS-PPESGASLD---EEGNP--GEG
DSLVDPFLSSSRAQPTLLVDWPKTPVSRAVFQGYTSS-GITGPAVTIKPYSLSSGETYVL
QASVATK--HGLLGKAQLYLTVNQAPQHVTCQVQPHQGL--EAHTLFSVFCMSGEPDFEY
EFSYQIGDTP-RHILYHGRDTQYYFALPAGEPMDSYQVMVSAEITDGRGSKAQPCAVAVT
VLPQYRG-----MDCPGEDLYNSSLKSLSTLQLMGSHMEARNYITMFTR-ILSRLTTEDG
NA-SCGQWSLIQDALISSLCAFASSDQEELMASVLMLRDLVGLPRRLSSTSMLLILRYAR
GLLARS---RLPAGLVLSRGLRLELVQLL-STVWDASGQEGAMVAQAHVQEEGMELASAL
LLGCLSLN-----RVSARQVEFLTMLHYSLQRSVHSLGPIRVYLPGDLA-GPRATWEETR
SPCYISQLVLFRKNPHPWGGHAPGQVGEA-VGLTLHACSGRRPIRRHRLASPVTVEFGE-
-DGGSDGQGNRMPFVLLRDEVNVHEFALGLSGDARETLQMRVEFSKPASRAFPVLLLVR-
FSERPTPSAFLVKQTHLWEERTLQIYIPAAAWKE-------SQVGFLSLLDADYDKRTPN
KHLAEAVHYTVRFQWLRCLLWD-EGEWESSRSSPEPGTSPDTVXXXXXXXX-XXXXXXXX
XXXXXXXXXXXXXXXHPQNLVPGVCVAVLVVLYGLLAVKSRLVDCREKKKAGCVFLQGSV
P-PGHQLYAIVVDTGFRSPARFSSKVYI---VLCFEDGCSPTRELHCPER-PLFE-----
-RNSRHTFMLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
--XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXPHDL-TFRAFRLGLLCSLLASPGAQLLSLLF
RLSKAPGAA-RVQHT---PLGA------------------------------QMEG---A
QHPASAILERDG--ARRKATSRP-------------G---TARPP--WEPEALGAAQGEP
VLREQS---HRCPSHPPRI--L-----------------EAKLDAWAICSVASLACALAT
AILGYRFETAQCVWWLHLLFLSVVCCCFITQPLMICV-VALSHAWKRRDDSH--------
---FFAESLHKATRNL-DSGLEGCSRTHD----SLPGSPCCAGSAGHIAEVLAARQRARR
LRW--VRPPSRAQLKVTRERTKRESRTWAALR--DVTVLALRLLLLLCVMSGRSSWD-AG
SLNQAVRKWFTRSGA-CLGSLQSVDGWWDWSLAVLLDGLHTAG----PSMAAQPGALGGT
CHLLGTPVIRQRSAAPHGLCKPLRLSAAMFEDTPSTQNPQV-EGPQS-------------
--GN------GSHG----GL--VGCVHS

PF08016 // ENSGT00700000104221_7_Domain_7 (2669, 2740)

LGRTRG--EVQAALSGLRASRWIDHSTRSVSV
CFTLFHTPSRLFTSVSLGVEILPSGALVPSSQVDSVSILRGDSVLGHCL--------MLS
E-LASLALSLAHLCFQLYAMVDKGVLNYWRKPRNWLEXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXRVRWMQGALSFLLLWTSLALLGRLVLPASLSL---M
LGHTLSRARAHAPLLAGILLLAAHAGITRRWQLLSTWAPAS-SAWAGALPC--LLFRFPG
RSRAHLPPAL---SQSNPQATACSC--LVLFTVLATLCFGVLRGALLIAPRR-RASPRRQ
ALRRLEHGRACTWRKALVWLGLGTPQSEETEVAEDHRY-HLD-EFANLVDELLMKVEGLS
SSLHLPPLERPRP------SAESRAEDRPLGGGPSPYQMAG-------------------
-------------------

KTSFP-TADKSVKGLSEHQERNLWTSCLLSLDSLLTVRARKNRGFHLCNCS--PPGVQT-
--GVCADHVLLVSDEGSDWPPCVLKGQAD-VEFKNSSSLASWEKNILKTTSKAMLNC---
-----VHGKTPTSPDWDNS--AGRMHHELSIIEIFSSGPSSIC--QMYAIGEANIIFFNL
L---EFKWNFLALRHLKTEVSNCVIRLLYSAEDVAGM-----LPGTV------KMGSQVK
VALSLLG-------LISHLLALP----RSPDSAPPGTRQTLS--FSASELDPKKLYPITL
CLPGTIPSQAPLSMANPVTLQLPETDTQ---NLGFHIQMASGAALCLAIDFGDDSVVQMR
IRNVSEEIVVTACHQYRKXXXXXXXXXX----XX-XXXXXXXXXXXXXXXXXXX------
X---XXXXXXXXXXXXXXXXXXXXXXXXXGVYVFKADVYDGFYGNNVELGPYYVEIGHGS
ISVFMNSSSIHEDEVLVSADSHIDQKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRKQLFIVREPCQPPL
VRNLGPGKVQIWRSQPLELGVIFEAAILCDISQGISYTWRFVRSDGSPVTLPPAVDCHRQ
AIALSGYFLEYGNYTAVAKVQIEGSVVHSNYSVGVEVRPRAPVSVISEGTHLFISKT---
PSSTIVLSGSQSYDP-----DHPGMTLSYHWRCTPASKPDRPCFNASPPSQLDTMAPIIS
FAAKDLSSSYDQFLVTLIVSNGGWNSSEAQVFLSIRSDSVFXXX--XXXXXXXXXXXXXX
XXXXXXXXMWWNSDGVPNLSYTWDLFLVNATEKNSMEXXXXXXXXXXXXXXX-XXXXXXX
XXXXXXXXX----------XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX-----XXXXX
XXXXXXXXXXXXXXXXXX-----XXXXXXX-XX------XXXXXXXXXXXXXXXSPQGAP
TPSSSSYLSDFEAYYSDIQEAI-PSKGRQPGN--KSH-LPGSEPGES---ANGNP--SDG
DNIIDPFHSTDIAIPSLMVDWSKSLISQATFQGYTSS--TTEQTVTVKPFSLRSGETYVI
QASVASK--HGLLGKAQLYLTVNKVPQDVTCQVQPHRGY--EAHTLFSVFCMSGIPDFHY
EFSYQIGNAS-KRTLFHGRDVQYYFALPAGEPLDNYKVMVSTEITDGEGSKLQPCAVAVT
VLPRYHG-----SGCLGEDLYNFXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XX-XXXXXXXXXXXXXXXXXXXXXXXXKEMVDSVLMLSDLINFPNKXXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXXXXX------------X--XXX-----XXXXXXXXX------
----XXXXXXXXXXXXXXXXXXXXXXXXXPQNSIQSIGPLRVHLPGDLA-RLSPAGTETR
STCYISQLILFRKNPYPGGRAAGQXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-
-XXXXXXXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX-
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------ASPGYLALLDADYDIKPPN
KYLAKAVNYTVHFQWIRCLLWD-KKEWTSESFPPQPGTSPEKVNCSYDRLT-AYAVLRRK
LNASFEMSDIFELQSHTENLLPSIFIVFLMMLYAFLATQSKCVDRHEKQKMGYIFLQENT
P-SDQ

PF01477 // ENSGT00700000104221_7_Domain_6 (1926, 2056)

QLYAVVIDTGFRAPAQLSAKVYI---ILCGENGLSETKELYCPEK-PLFE-----
-RNSRHTFILSVPEHLGPLRKIHLWHNSCGPSPDWYISHVMVRELPTR--HSWFFPAECW
LAVSHGDGRVERELVCLRRGLGFWKLLYSKFTEYLEDVHVWISVYSRPSHSRYLHTPRLT
VSFSLVCVYSCLTAVLTAVEQEQLPWGVGPADV-TLGPFGVGLLCTLLASPGALLLSLLF
RLSKEAIGP-SPE--------------------------------GPWGSPGRVQR---E
ATRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX
XXXXXX---XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXFDPEQCGQWLHLLGLSMVCCVFLTQPLMICF-MALSFAWRRRDDND--------
---FFNESLQDATKNL-ESELEQ-----------LSSNCCIPDCASEFEKXXXXXXXXXX
XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX--DILWSILMLLLLLFIIYGKFSQD-EH
SVNQAIRNEFTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXXXXXX
-XXX------XXXX----XX--XXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--------XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXRTRWLQGILLFLWMFKCIYLLGLRKTMASCSL---T
IHRLIS--SIIAPGLAGVLVLTALSHL-HRLLLFFTQPLPS-SSFVDSVPR--LLSPRLG
RSPGEAFFGL---YESSQRAMACYY--GAFCTVTAILWFGMLKGSLLTFARK-RKSSRSK
DLVSL-DITTYVWEKTLTFLGLERPTLEDTKMVENHKY-YLE-EFSNLLDELLLKINGLS
NSLQLPSLEEPPI-----STAETRTGDDPSVVTS-DYHATG-------------------
-------------------

------------------------------------------------------------
----QASPEPCVSDAQDSCPSYAPKGTAGDPESQTPSSAAPWNKNILNTTSEGRLSFTNR
--------EPQTPPEWDEAT----------------------------------------
------------------------------------------------------------
---------------------------NSFSDPP--PGISQTRNLSASWYHPESSCPLTQ
HPLGAVLATQPENAGHFATCCFPETDAKAPPALGIRVHAASRTALCLLLDFGDNHGAEMK
LSTVTGAATMTGYYQYRTEGV---------------------------------------
-------------------------------YKLKV-VVSDCHGADEELGPYYMDIGHGN
VSVFMNSSSIHNNESLAFANSLPQQEGTVVVHCFSSVSSYNVSFMSQTRVGSSQAWSGVT
VGYTMQSVSVYTNGTVFAADTNITFVAVTEETVPLEFTWYFGENPPVTTTSRSIR---RR
LSIPQWYRVMVKATSRMGSVVSEPHLIRVQKRILANRLVSTAS

PF00801 // ENSGT00700000104221_7_Domain_1 (644, 704)

ALVNANVSFECRLNFGT
DVAYLWNFGDGSIELGSSSSGHVYDREGEFTVEVLAFNNISSA

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQIFIVQEPCQPPP
VKNMGPAKVQIWRSQPLRLGVTFEAAII

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1408)

CNISQGLSYTWSFVGAEATAVTLPAAVNTHRQ
TIMLPSYTLECGNYTAVAKVQIKGSMVYSNYCVGVEVRARAPVSVISEGTHIFLSKA---
TSTSIILSGSQSYDP-----DNPGAALRYHWTCTAASSPIWPCFDDSTSYQMDTQAPAIS
FPAKWLSECCDQFLVTLTVSSSGRNSSQALTFLSTRPDLAFRFI--HVSWVNFRDISVNW
NEEVSLRAVCEDCGDVSDLTYSWDLFLVNATEKNAVEVPFCSTVGLLGASAL-GASLKSF
ESHQPSN----------------VR-ASPTPHSLGPSPTPLGWTALSNLG-----SISAE
SPAGGHHIPAAGPVAGSG-----EPMEDYGSLSPAPSSLAEEALMMSDP------EGSWP
FPSSSTAFDDFEAYYSDIQEAV-PSLGRQPGI--SAN-FQEAGSSLSA--E-ESA--SYG
DNLLGPFLHTGRAKPTLMIDWPKALVSRAVFHGYTTS-GIMGPDVTIKPFSLSSGEMYVL
QASVASK--HVLLGKAQLYLTVNQAPQDMSCQVRPHRGM--EAHTIFSIFCMSGKPDFHY
EFRYRIGNAS-SHTLYRGQDTQYYFLLPAGDSSDSYKVIVSTEVTDGQGSKVQPCTVEVT
VLPRYHG-----NDCHDKDLYNSTLENLSTLQLVGSYTEIRNYIAMITG-ILSRLYVESR
NTSSCGQWSQIQDVLIFSACKVPYTDQETMMDSIHILRDLISFPNKLSLMSAELIYKYAQ
MFLAQG---QVSRRLLVDEKLRVEFILLI-SGVWEAAKED-VRD-GYYLQKEGMKIVSDM
LLACLSLSPKHQIHISTGQMEFQTLVHRSPQSSIQNLGFIRVHLPNDVA-LHSPTQEETQ
SPCYISQLTFFMKSPYSGEQAPG-QLGGV-MSPWLYSCKSRRPILRGRLETPVTIEFGE-
-EDHL-HKKNPAMFVLLRDEVNVHQFT-GLSENSQESLQIHIEFSKPVIRAFPIILLVR-
FSEKATPSDFLMKQVYFWDEQTVQMYVPAAPWRG-------ANVGYLSLLDADYDRKPPN
KYLAGAVNYTVHFQWIQCVFWDK-TEWRSEGPCPQPGTSPEKVNCSYHRLA-PFSVLRRK
LNATFQVSSVSEFQSHPHNLLPSIFSVFFLVLYGFLMSKSSCVDCHKKKDPGCIFLEEEA
L-LGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2045)

YAVVIDTGFRSPARFTSKVFI---VLCGENGHSETKELCCPEK-PLFG-----
-RNSRHTFILSTPHQLGPLQKIRLWHDSSGLSPSWFISHVMVKELCSG--QAWFFSAQCW
LAVS

ENSGT00700000104221_7_Linker_6_7 (2045, 2665)

KRGGQVLGEFFCLSHGLSFWKLFYSKFTEYLEDFHIWFSLYSQPPSSNYLHTQRLA
VSFCLLSVYSCLTALVTVGGHEQRPLGVGPTAI-TLDSFSLALLCTILACPPAQLLSLLF
RCSKEARGH-LRTSRQ--WPLR--GVKTEVPQGPDPG--------GK---PDSRQP---S
PHPISDLLPGTDQAWRMTAS--------------NSG---IVHSS-FP-LEACRDKHL--
ALRERS---HCSPPSSQAP--SSGFEEL-RPQQSRVCLLWSSSVAWAISGTASLACGLGT
GFLGYKFVPAQCVWWLHLLLLSLVCCALITQPLMICL-AASAFAWKRKHDSE--------
---FFTESLQDATKGL-DLELEERSRTHI----PLSPVSYSPDSAEEAERVLAARQRERH
LRW--AQTPSGPKFRVMRERLRRERLMQAALR--DVTMHSVMLLLLLFIAYGRFCPG-EY
SLNQAIRRAFTRNAHHSLGDLSSTEDWWDWTLSTLLDGLHPERMPA-TAWGSQPGALGGQ
CHLIGPSVIKQLKVSAGTACVAPKPFSELVEDVLPMHSHAL--D--------LENRNVTP
-DDP------KTCG----VKK-ES

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2881)

YTHSLGRTRH--EAHAALTALRASRWIDHSTRAVSV
HFTLYNPPTRLFTSVTLGAEFLSTRGLVSSSLIESFSIFYRDSALQCLL--------MLS
E-LLFLVLNMIHLCFQLWEMATKGILSYWRKPRQWLELSMVGVALAYCAASGHLTTLAEN
ITDQFHKGLYQRFVDISLMVSWNQRARCLQGILLFLWMLKCVHLFSSLSTMAPFSA---V
TCSL-----LFRVLLVGALLLAAHSHL-RWFLL-YTSTLSR-GTSAEAFPG--LLLQFPG
RSQKDSQHNH---LESDHRAVNCYY--GTLFLLLATLGFRMLRATSLTLFQDR-KSFHRK
SLVTLKDVAVSMWHRLLTFLRLETTTSGETEVTTDHIY-YLD-EFSSLLDELLMKIDGLS
DSLELSILEKQWR-----RTVESRTGDSPSVGIL-EYQAAGCSTPLFLR---------SE
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------Q

PF02010 // ENSGT00700000104221_7_Domain_2 (800, 1393)

VQIKGSVVYSNYCVGVEVRPRAPVSVISEGTHIFIPRA---
TTTPVVLRGFQSYDP-----DNPGAALRYHWTCTAASSPRWPCFEDSTLYQVDTQAPSIS
FPAKWLSECCDQFLVTLTVSSNGQNSSRALIFLSTRPDPAFRFV--HISWVHFRDTRVNW
NEELSFRAVCEDCGDVPDLTYSWDLFLVNATEKTTVEVPFCSTVGLLGSSAF-GALLKLP
QSGLQSN----------------SR-GSLALHSPQQSPVPPSWTALPNLG-----STSTE
STAADPHIPMADPLAGSG-----ELMEDYGSLN----SLEEQALMMSTP------EGSWP
PSSSSPAFDDFEAYYSDIQEDV-PSQGRQPG----TN-FHESGPSMVA--E-ESA--SDG
DRLLGPSLHTGRAKSALMIDWPKTLVSRAVFHGYTSS-GIVGPAVTIKPFSLSKGEMYVL
QASTASK--HVLLGKAQLYITVNQVPRDMSCQVRPHSGL--EAHTIFSVFCMSGRPDFHY
EFHYQIGNTS-PHTLYRGRDTQYYFLLPAGETSDNYKVIVSTEITDGQGSKVQPCTVEVT
VLPRYHG-----NDCPDKDLYDSALETLSSLQLVGSYTEVRNYIAMATA-ILSRLHAESR
NTSTCGLWSQIQDVLVSSACKVPFTDQEAMMDSIHILRDLINFPNKLSLMSAMHILKYAQ
MFLTQG---QFSRKLLVNKKLGVELILLI-SGVWEAAKED-TTN-EDYLQEEGMMIISDM
LL----------LHISTGQAEFWTLLHHSSQSSVQNLGFIGVRFPRDMA-LHGPAQEESH
SPCYVSQLMVFRSSPYPVGQAPG-QVGAV-VRPRLYSCKSRQPILRGRLEMPVTVEFGE-
-EDHW-HKRNPTMFTLIRDGVNLHRFV-GLSEKPQETLQIRIEFSKPVTRAFPIMLLVR-
FSKKATPSDFLVKQVYFWDEQTVQIYVPAVPLKG-------ANVGYLSLLDADYDRRPPN
KYLAGAVNYTVNFQWIQCVFWDK-TGWRSEGPHPQPGSSPEKVNCSYRRLA-PFSVLRRK
LSATLEVSSISGFRSHPRNLLPGIFSVFLLVVYGFLMTKSRCVDCHKKKKPGCIFLEEDT
P-PGHQLYA

PF01477 // ENSGT00700000104221_7_Domain_6 (1930, 2045)

VIVDTGFRSPAQFTSKVFI---VLCGENGLSETKELCCPQM-SLFG-----
-RNSRHTFVLSTPNQLGPLRKIRLWHDSSGPSPNWFISHMMVKELHSG--QCWFFPAQCW
LAVS

ENSGT00700000104221_7_Linker_6_7 (2045, 2665)

LCDGRVQRELFCQRHGLGFWKLFYSKLTEYLEDFHIWLSLYSQPPSSSYLLTQRLA
VSFCLLCVYACLTALVAVGVGEQRSLDVGPT----VESFSLGLLCTTLACPLAQLLSLLF
RFSKATAGH-GRAAPQ--WPLG--GVKTEAPQGSDHS--------GR---QSWRQP---F
QHPASDILPATDGAWRMVAS--------------GSG---VACPS-FL------------
AVRERN---HQPPPSSQAP--SSGFKGP-VPQRSRVCLLWSRSVAWAICGSVSLSCGLGT
GFLGYRFVPAQCVWWLHLLLLSVVCCMFVTQPLMICL-AALAFAWKRKHDSQ--------
---FFIESLHDATRDL-DLELEEYSRAHI----LHSGSSCSPDSAEEAGRVLAARQRERH
LRW--AQPPSRAKFRVTRERLKKESQMQASLR--DLSMHSLTLLLLLFITYGRFCPG-EY
SLNQAIRKGFTSTSKVLCGA----------------------------------------
---------------GGTMAQPSRALAALPEDS--VLTHDL--D--------LENRNVTP
-GGP------EVCG----EKK-ES

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2759)

FMHSLGRTRH--EAHSALTALRANRWIDHSTRAMYV
HFTLYNPPMRLFTSVTLGAEFLPTGGLVPSSLVESFSIFDSDSVPQSLL--------MLS
E-VSSPALGPLD----------------WHRS--------LGFHTAKYPSRAR-------
-ALWVEQGLVLRKFKTAKAISWGQREEQKVGRILA-----------------ASSG---C
RWERCP--GVFSLQLLGSLLLAAHFHL-YRFLL-FTWTPSPGGTSTDAFPG--LLPQFLG
ISHRDSPHNH---LEPGRQAVSCYR--GALFLLVATLCFRMLRASLLTFFRKR-KSFHRK
SLVTLKNLAVYARHKFLALLGLEATTLEETELATDHSY-YLD-EFSSLLDELLVKIDGLS
DNLELSILEEQWR-----RGVDSRAVDSPSAGLS-GCQATGTFLTDSGP---------QA
GDLKCA-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------LPGTIMRGTPTAAARPAQ
TSA----QGASLWAVSRFPTFPPLLLFHSSQGLP--PGTSLNSSLSTSQSCSRRIYLLIP
CPPAVAQAQD-PDVMNHIICHFWETEAQAPLNLEFHVSMASGLALCLVMGFGDSSRVEMR
LHNTSEAMAVTACHQRETGTFFHA---AFWHFQIAKFFKQHTQ-----NSVECAALCHCT
GHSVECAALCHCTGHEFLKCPVSF-LFPEGVYMLKAVIYSEFSATGVELGPYYVEIGLGA
ISMFTNSSSVNE-DVLVFAGSHMNQKSTVVIYHFSSTSSCDVSFIYHTLVDGNQGWLSIT
VGYKIQSVSVYTNGTVFAADTDIVFAAVTKAMTPLEFAWYFGEDPPVRTTSRSIK---KR
FSVPQWYLVTVKASDRVSSVVSEPHLIRVQKTIVANRLVS

PF00801 // ENSGT00700000104221_7_Domain_1 (641, 704)

PASALVNATVAFECRINFGT
DVAYLWDFGDGTVTLGSSTSSHVYSREGQFAVEVRAFNDISAT

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIVSKPCQPPL
VKNMGPGKVQVWRSQAVRLGVTFEAAVL

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1404)

CDISQGLSYTWSLTDSEGSPVPLLAAVNTHRQ
TLVIPSYTLESGNYTALAKVQIEGSVVHSNYSVGLEVQAQAPVSVISEGTHLFVPRT---
ASPLIVLRGTQSFDP-----DNPEATLRYHWKCTAASLPGQPCFASSTPHRLDTWAPTFS
FVAKWLSGSYDQFLVTLTVSSGLRNSSEAQAFLSTRSDSAFRFI--HISWVNFKDTFVNW
NEELSLQAVCEGCGEIPNLSYSWDLFLVNATEKNRMEVPFCRAAGLLGSSGF-SAILKSS
EPSPLSSEP----------TMPDPD-VTATLSSRELSLETLSQTALSALG-----RPAPE
PTAGVPRIPAAGDSAVPG-----EVPKE-EPPGPEPGPRGEGALMTGPP------ERSGP
PANPAHHLSDFEAYYGDVQEAI-PSRGRQLGN--NAT-LPGSGPSLSV--EEETP--GEG
DNLLGPSASKDRAVSVLLVDWPKALLGRALFQGYAAS-GITEQTVTIKPFSLSSGETYVL
QASVASE--QRLLGKAQLYVTVNQAPGDVACQVQPPRGL--EAHTVFSIFCTSGKPDFLY
EFSYHVGNAS-THTLYRGRDSQYYFSLPSGEPLDDYRVLVSTEITDGKGSKVQPCAVAVT
VLPYYRG-----SDCLDEGLYNSSLKSLITLQLMGNYIETRNYITMTTK-ILSRLSKENR
TA-SCGQWSRIQDALISSVCKLAFANEEEMADSVLMLRNLISFSNKLSRVSAVLILKYSR
ALLAQG---WFSGRYVTDRGLRLDLIHLI-SRVWDISEQEQSRG-QDYLGEEAIAIITDV
LLGCLALT-----HISAGQMEFQTLLHHNLQSSVQSLGSVQVHLPADLT-GHSPAGAETQ
SPCYISQLVLFKKSPYPEPQAPG-QISGV-VGLTLYNCSSKRPINRQWLRKPLALEFEE-
-EVSPDQRRNTTTFVLLRDKVNFHQFT-GLSENPQESLQIEIRFSKPITRAFPIMLLVR-
FSEKPTPSDFLVKQIYFWDENVIQMYVPAVSQKD-------ANIGYLSLLDVDYDRKAPN
KYLVKAVNYTIHFQWIRCLFWDK-KEWKSGSFSPQPGTSPGKVNCSYDRLATAFSVLRRR
LNASYEASDISQLQSHPENLLLGIFIVVFMIFYGFLVAKSRRVDHYEMKKAGYIFLQEAP
P-PGHSL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2044)

YAVVIDTGFRAPARFTSKVYI---VLCGENGLSETKELYCSEK-PLFE-----
-RNSRHTFILSAPDQLGPLRKVRLWHDSSGPSPGWFLSHVMVKALHTR--QGWFFPAQCW
LSA

ENSGT00700000104221_7_Linker_6_7 (2044, 2665)

SWCDGRVERELTCLHGGLGFWKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VTFSLLCVYACLTALITAAGQDQLLLDVGPPGV-MPRPFRTGLLCAFLASPGAQLLSLLF
RLSKAAAGP-SQAEPL--GPMG--GAQTEATRGPNS---------RRR-TPDAQEM---S
RHHASVTVLG--NAWTKAAS--------------SDG---AACPP-PE-LEAHGANHGGT
ALRGES---RLCLPRSQAP--SSGLAGV-APR-RRAPLPWAGSAVWAICVTLSLGCGMGT
GFLGYRFSPAQCVWWLHLLSLSVACCVFVTQPLMICL-MALGFAWKRRDDNQ--------
---FFRESLCDATRNL-DSELEERSRTRL----LLSSSCGFPDCAAEVEQVLAARQQARR
LRW--ACPPSTAQLKVTRERMRRESRMQAALR--DLSTYILMLLLLLCITYGRFSQD-EY
SLNQAIRKEFTRNARNALGGLRSVADWWDWSLTVLLDGLYEGGPAAASGPGAQAGALGGK
CFLIGSPIIQQLKVSPSSSSKPLGTFSALTEDPLPTCNPEV-RGPKSPNLTEPQNQNVTP
-DSP------RGCG----AR--ED

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2872)

CVLSLGRTRR--EAHMALAGLRASRWIDGSTRAVSV
YFTLYNPPTRLFSSLSVSVEILPTGGLAPSYLVESFGIFCSDSAESHLL--------LLL
Q-LVLLVLSLVHFCLRLYSMMEKDVLICWRKPRNWLELSVTGVSLAYYVASSYQVTLARD
VIDQLHQGLSQVCLDLTIMASWNQRVRWLQGILLFLLMLKCIYLPGIHKTMVSCAS---V
KR---P--SVFVPVVAGALLLAAGSHL-RWALP-STGAPPS-GTFTGSFPG--LLLRLPG
RNQRDLFLGL---SESDSG-AARYC--VALSTVTTLLCLGMLKSSLMSLTRKR-KSSQSK
YLVRLKDVAAYTWEKAVTFLGLEIPKLEEVEMAENHNY-YLD-EFANLLDELLMKINCLS
DSLQLPLLERQSS-----SVREGGAEDRRLVGIS-SYQTTEVRTY---------------
-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------GSVV

PF02010 // ENSGT00700000104221_7_Domain_2 (808, 1393)

YSNYCVAVEVRPRAPVSVISEGTHIFIPRA---
TSMPIILRGSQSYDP-----DNPGAALRYYWTCTASSLPGWPCFDDSTPHQVDTRAPAIS
FPAKCLSECCDQFIVTLTVSSNGQNSSQAQVFLSTRPDPAFRFV--HISWVNFKDIGINW
NEELSLQALCEDCGDARDLSYSWDLFLVNATEKSGMQVPFCSTVGLLGTSAL-GAILKFS
EPNLQED----------------PS-GSLAPHSLEPLRMTLDWPAPSILG-----RTSTD
STAASHETPAPGLMAGPD-----EPSGDG-SL----RSLGEEVLTVNTP------EGSWP
FPSSSPAFDEFEAYYSDIQEAL-PSRGRQPGN--STN-LLGSGPSMNA--E-ARP--SDG
DNLLDPFLHTGRAEPALMIDWPKTLVSSAVFYGYTSS-GIMGPVVTIKPYSLSSGETYVL
QASVASK--HGLLGKAQLYLMVNKAPQDMACQVQPHHGL--EAHTIFSVFCMSGKPDFHY
EFRYWIGNAS-SHSLYRGQDTHYYFSLPAGETSDNYKVIISTEITDGQGSKVQPCTAVVT
VLPRYHG-----

ENSGT00700000104221_7_Linker_2_5 (1393, 1816)

NDCPDEDLYHSSLRNLSTLQLMGSYMEIRNYITMVTG-ILNRLAKESR
NT-SCGLWSQIQDALISSACQLPFTDQEAMMDSIWLLRDLISIQNKLSFMSAMCIFKYIR
LFLAQG---QLSGRFVVNRNLSLELVLLI-SGVWEAAKQGKMRN-EDYLQEEAMKLISEA
LL--------HRFHMSTEQMESWTLIHRTLQSSVQNLGCVRVHLPGDLA-WHSSAQEETQ
GQCYISQLMFFTENPYPGGRSPG-QVGGV-LSLMLYSCSSRKPIRRGRLETPVTVEFGE-
-EDH---PRNTTMFTLLRDEVNLHRFV-GLSENPQESLQICIEFSEPVTRAFPIMLLVR-
FSEKPTPSDFLVKEIYFWDKQTVQIYIPAIPRKG-------SNVGYLSLLDADYDRRPPN
KYFARTVNYTVHFQW

PF01825 // ENSGT00700000104221_7_Domain_5 (1816, 1857)

IQCVFWDK-TEWRSEGFSPQPGTS-GKINCSYHRLT-PFSV

ENSGT00700000104221_7_Linker_5_6 (1857, 1928)

LQRK
LNSSFEVNSISKFQSHPQNLLPSILTVVFMVLYGCLVIKSRCVNRHERKKTGCIFLKEDS
P-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAIVIDTGFRSPAQFTSKVFI---VLCGENGLSETKELYCPER-SLFE-----
-RNSRHTFVLSARNHLGPLRKIHLWHDSSGPSPSWFISHVIVKELRSG--QAWFFPAQCW
LAVSQH

ENSGT00700000104221_7_Linker_6_7 (2047, 2665)

DGCVQRELTRLCHGLGFWKLFYSKFMEYLEDFHVWLSPYSQPTSSSYPHTQRLA
VSFCLLCVYACLTALVTVEGHEQHPLDVGPTNI-TLRSFSLGLLCTLLASPGAQLLSLLF
RQSKEALGH-PWADSQ--GRLR--EAKTEAPQGPTLS------------------Q---F
QNPASHILSESDQAWRTAAS--------------GND---VAYPS-LQ-LEACGDEEL--
TLREKI---HHSPPTLQAP--SSDSEGF-WPQQSRAYQPWTSSVAWIICWSVSLACASGT
GFLGYRFVPTQCMWWLHLLALSIICCVFVTQPLMICV-VALAFAWKRKDDSQ--------
---FFTESLCDATKDL-NLELE-YSRIHD----SSSSSYCAPTSAGEAEKILAARQRERH
LRW--AQPPSTAQLRVTRERLRRESHMQAALR--DVCMHSLLLLQLLLLIYGRFCPG-ER
SLNQAIRKEFTRNARRSLEDLSSTDDWWDWTLSTMLDGLYPGGSSA-GAWGAQPDALGGQ
CHLIGTSVIKQLKVSSSPGCKPHRPFSAFMEDSLHIPNPEL--D--------FENRNMTP
-GGP------EACR----MRR-ES

PF08016 // ENSGT00700000104221_7_Domain_7 (2665, 2862)

YMHSLGKTRL--EAHAALTALRTSRWISCSTRAMSV
HFTLYNPSTQLFTSVSLGAEVLPTGGLVPWSLVESFSIFRSDSVCQYHL--------VFS
E-LMFLVLNMTRLCFQLWEMATKGVLSYWRKPRHWLELSVSGVALVYCAASGHLTTLAGD
VTDQFRKGLCPMFVDFSLMALWNQRVRWLQGILLFLWMWKCILLPGFLNTTVSSPV---I
----RP--SLSRLFLVGVLLLATHCRL-CRFLL-FTWMPSS-WTSADVIPG--PLFGFLG
RSQKDSWQDL---WESDQPDMAHYL--GALFLLAATLCFGMLRASVMTFFRKR-KSVYRK
SLVTLKDVAVYLWRKVLTFLRLETPGVEETEVATDHNY-YLD-EFSTLLDELLMKIDDLS
DSLEFSILEEQLR-----RRMETGKNADI-------------------------------
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-----------------------GTMVHSNYSVGVEVLARVP

PF02010 // ENSGT00700000104221_7_Domain_3 (823, 994)

VAVISEGTHLFVPRA---
AREPVVLRGTQSFDP-----DHPGAVLSYHWTCTAARSPGRPCFDDTGPNQPDTRASIFS
FAVERLSTCCDQFLLTLTVASRGQYSSEAQVFLSTRQDPGFRFL--HISWLSFKDVYVNW
NEELSLRAVCDDCGETLSLSYSWELFWVNATEK

ENSGT00700000104221_7_Linker_3_4 (994, 1218)

SSIEVPLCSTVQLLGVAAL-RAFWESP
ESALSAMEP----------SEELPV-GTPTPLPWGTPPEAL--------H-----HTVLG
SSAS-------------G-----EA-VEDQPRGPEPVAQAEGAPPTMSP-----SSRSQP
QPSSPPALDDFEDYYGNIQEAE-PAGGRQPGHSTGV------SSADA---AEGSP--GEG
DNLLDPFTSADRASPVL

PF02010 // ENSGT00700000104221_7_Domain_4 (1218, 1389)

TIDWPKARLSRAVLRGYTEA-GITKPTVTLKPYSLSSGETYVL
QASVASAAEPSELGRAQLYVRVPRVPRDAACQVQPQRGL--EALTIFSVFCMSGTPDFHY
EFSYWVGNAS-RHTLYRGRDTQYYFALPAGDPLDNYKVMVSTEITDGQGSRIQPCSVAVT
VLPRYYGNSD---SC-ASSRYNSSLRNLSVLWLMGSDTESRNYIAMLTG-ILSRLAKENT
ST-SCDQWSPLQDALISAVCTLAFADEEEMMDSVHTLRNLVNLPIKLGFLSAARILRFAH
TLLVQDQT-HFSGKFVGAGGRRLELILLI-SGVWEASEHGTWRH-EDYILEEGKRVISDM
LL----------LSVSAGQMEFRVLLHRGLHCSVQSLGSVLVHLPRDLA-GLSPAAEETQ
APCYISQLTLFRRRLHPGGGAAG-QVGGI-LGLSLYSCPSRSPIRRRQLRTPVTVEFGD-
-EDS-GVRMPSSSFVLLREQVHFHQFA-LLSQHPQELLQIHIEFAELETPAFPVLLLFS-
FSKKPSPSDFLVQQTRFQDQQSVRIFAPTALGRA-------ANVGYLSLLDAYYDRRAPS
TFLAKAVSYTAHFQWIRCLFWE-RGEWKSGRFSPQPGTSPDKVNCSYDRLA-PFSTLRRR
LNASFEASDISEVQSPPQNLLPSVCMGVITVLYGLLVMKSNLVDRRKEKGPGYIFLQEAA
P-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2048)

YAVVVDTGFWSPARFTSRVFI---VLFGESGLSETRELCCPER-TLFE-----
-RNSRHTFILSAPAQLGPLWKVRVWHDSSGPAPRWLLSCVMVKELQSG--RAWFFPARCW
L----GDGRVERELPCLRQGLGFWKLFCAKLTEALEGCHVWLSLCGPPRSHGPSRTQRLA
VSLCLLCTHACLTALATAGGRDQLLPDV------VLGDLGLGLLCALAASPAAQLLPLLF
RCSQVPARG-SQARRTP-GSWSLRSALLGVPHAPQPT--------LCWPWPPSRGP---L
PHPG---------SPS---------------------------------LLSWG------
-----------TGSHCPSP--SDGHEGL-EPQGPSACQPPPNTAAWTICGMVTLACGLGT
GFLGYRFLPAQCAQWLLLLSLSVVCCAFITQPLLICC-AALGFAWKRRADSQ--------
---CFAESLREATEHL-VPFRTLKVSERK----PMQM----SPSTAADAPVLAARQRERH
LRR--ARPPSRAQLRVTRERTKRAHRAQAALR--GLAMHGLTLLLLTWLTHGAFSTAAEH
ALNRAIR-------------------------------------------KALPGALGGK
CYLLGASVIQQPQD-------PPRPSPAPLEDSLPLWSPDP-RGLED--------QNLTH
-GGP------------------GHCLLSPGRTRL--EAQALLSTLRARGWAAA-----SM
RLVLYHPPSQLFTSIALRAQPLPAA------WVESFRVFWVAQARLKHVVLLSLSEIPCP
LQLACLVLSLARLSLHLYSMAEVGALSYWRRPRNWLELPALGAALAYYAACGLLSLHAGD
VAQQLRGGPCQGPLDLSLMALWSQRARWLRGLLLFLWTLRCISLPGLLHTWKLTPPFLST
WGRSSGSWLFSLLQLVGALVLAAHTHL-RHL-LSAAWTLPP-RTFAHSGSRLLLLLGLPG
RSQEDSSPSL---PTSHLI---CLF-----------HSLLQLRVSLLTCFHK-SKSSRGN
PPVRLTDVAALSWQEALAFLGLETPAAGEMEAAVDHVCLGLDTEFSSLLDELLVKVEALS
HGLELPALEEPRP-----------ADDSPAVTPG--------------------------
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------------------------------------------------------GALGGK
CYVLGAVLIRQQREASGDTGEPPGPASALTEDCPPPHGPKA-GGPNAPSATDPATQTVAP
-SGP------GDCG----AR--ESWEL

PF08016 // ENSGT00700000104221_7_Domain_7 (2668, 2982)

SLGHTRP--AAHAALSGLRAHGWIDHSTRAVSV
HFTLYNPPTRLLSSVSLRAELLPTGDLALSPLVQSLAVFGSDSALWSSP--------PLP
E-LAFLLLSLTHVCLQVWSLAEDGVRRYWRKPGNWLKLAILGANFTCHAASSHLATLTED
VMDHFRRGHFQGFTDLSLAASWNQRVTWLQGTLLFLLTLKLAFLVGIQSSTACCSL---L
LRRSRA--G---------------------------------------------------
------------------------------------ICTAGLRGSLATLAQK-RKSFQSQ
SLVSLADLTAYVWGAVLARLEARKPPQEEADVATRRNH-YLD-EVSDLLDELLWKIHGLS
DRPQRPLPRQRSG-----DTGGAGPGGHPLGGVSA-------------------------
-------------------

----------SSLEASQTVFECLQAACCLSFNGELSVSTDKSWGLHLCSCS--PPGGGLW
VE-VYANHVLLMSDGKCDCPRCALKRQAEDRESQSPSSLLSGQKNIWKTTSKAALSVVN-
-------EKTQAPLDCDNSADRIPRKPSIIIVRAWSSGGPRFHHRWLCATGTTDSTFSGL
LQ-VQGTSSAAAPCNLKMEASCCVLRLLCCAEDTATGL----LPGTVTMETPTKVARPTQ
T--------IPLWPIS-----RFPTSPRSSHSLP--PGTPRTPSFMALQSGSEILYPPTQ
HPPVAILAQHSDNSMNPVLDCSLEMEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEMR
LHNMSEAMAVTAYHQYSKGKVIF-FLLLHFQLDISTYKEAETK-----NMTLKVYLCQSE
NS---CQE---DSDPSNLGYELIFAFVTKGVYMLKAVIYNEFHGTKVELGPYYVEIGREA
VSAFMNSSSVHEDEVLVFTDSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT
VWYRMQSVSV

PF00801 // ENSGT00700000104221_7_Domain_0 (551, 620)

YTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIK---KR
LSIPQWYRVMVKASNRISS

ENSGT00700000104221_7_Linker_0_1 (620, 640)

VVSEPHVIRVQKKIVANRLM

PF00801 // ENSGT00700000104221_7_Domain_1 (640, 704)

SPSSALVNASVAFECRINFGT
DVAYLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNISAS

ENSGT00700000104221_7_Linker_1_2 (704, 749)

TLRKQLFIGCKPCQPPL
VKNMGPEKVQIWRSQPVRLGVTFEAAVF

PF02010 // ENSGT00700000104221_7_Domain_2 (749, 1407)

CDISHGLSYTWNLMDSEGLPVSLPAAVDTRRQ
TLILPSHTLEYGNYTVLAKVQIEGSVVYSNYCVGLEVQAQAPVSVISEGTHLFFSRT---
TSSPIVLRGTESFDPD-----NPGATLRYHWECTSASSPAHPCFDSSTAHQLDAAAPTVS
FEAQWLSDSYDQFLVMLRVSSGGRNSSEARVFLSPYPDSALRFI--HISWVSFKDTFVNW
NDELSLQATCEDCGEILNLSYSWDLFLVNATEKNKIEVPFCRVVGLLGSLGL-GAIPKSS
QSNLLPTEP----------GTVDPD-ATTTPFSREPSLVTLGQPAPSAPR-----GTPTE
PVTGVYWIPAAEDSAVLG-----EAPEE-GSLDLEPGPQSKGSLMTGPS------ERSQP
SHSPSPHLSDFEAYYSDIQEAI-PSGGRQPAK--DTS-FPESGPSLSA--K-ESP--GDG
DNLVDPSLSVGRAKPVLMIDWHKALLSRAVFQGYSSS-GITEQTVTIKPYSLNSGETYVL
QASVASK--HGLLGKTQLYLTVNPAPRDMVCQVQPHHGL--EAHTIFSVFCMSGKPDFHY
EFSYQIGNAS-KHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGEGSKVQPCTVVVT
VLPHYHG-----NDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITR-ILSRLSKEDK
TA-SCNQWSRIQDALISSVCKLAFVDQEEMIGSVLMLRDLVSFSNKLSFMSAVLIFKYTR
ALLAQG---QSSGPFVVDKGVRLELIGLI-SRIWEVSEQGNSKE-EGYLHEEGITVISDL
LLGCLPLN-----HVSTGQMEFRTLFHYNLQSSVQSLGSVQVHLPGDLA-GHNPAGAETQ
SPCYISQLILFKKNPYPGGQAPG-QIGGV-VGLNLYTCSSRRPINRQWLRKPVMVEFGE-
-EDGPDNRRNKTAFVLLQDKVNLHQFT-ELSENPQESLRIEIEFSKPVTRAFPVMLLVR-
FSEKPTPSDFLVKQIYLWDESIVQIYIPAASQKD-------ANVGYLSLLDADYDRKPPN
KYLAKAVNYTVHFQWIRCLFWDK-REWKAEHFSPQPGTSPEKVNCSYDRLA-AFALLRRK
LKASFEVSDISKLQSHPENLLPSIFIMGSLILYGFLVTKSRQVDHHEKKKFGYIFLQEAP
L-PGHQL

PF01477 // ENSGT00700000104221_7_Domain_6 (1928, 2047)

YAVVIDTGFRAPARLTSKVYI---VLCGDNGLSETKELSCPEK-PLFE-----
-RNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELRTG--QGWFFPAQCW
LSAGRH

ENSGT00700000104221_7_Linker_6_7 (2047, 2666)

DGRVERELTRLQGGLGFRKLFYCKFTEYLEDFHIWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTAVVAAGGQEQVRLDVSP----TLGSFRVGLLCTLLASPGAQLLSLLF
RLSKEAPGP-ARAESHC-PPRG--EARAEAPQGPNS---------YQR-VPDAQEP---C
KHPASAIVSGSGRAQRKAAS--------------DDG---TACPA-PK-LEAHGADHSRT
TLMGKS---HCCPPCTQAP--SSGLEGL-MPRWSRAPQPWWSSAVWAICGTASLACGLGT
GFLGYRFGQEQCVRWLHLLSLSVVCCVFITQPLMVCL-MALGFAWKRRADNH--------
---FFTESLREATRDL-DSELAERSWTRL----PVSSSCSIPDCAGEVEKVVAARQQARH
LRW--AHPPSKAHLRVTRERMRRESRTQAALR--DISMDILMLLLLLGIMYGRFSRD-EY
SLNQAIRKEFTRNARNSFGGLRNITDWWDWSLTTLLDSLYPGGSPATRVPGAQPGALGGK
CYLIGSSVIKQLKVFPSHVCKPPRPFSAPIEDSIPTCSPEG-GGPENPYLIDPENQNVTL
-NGP------RGYG----AR--KDC

PF08016 // ENSGT00700000104221_7_Domain_7 (2666, 2876)

VLSLGRTRP--EAHTALSRLRASTWIDHSTRAVSV
HFTLYNPPTQFFTSVSLSVEILPTGSLVPSCLVESFSIFRSDSALQYHL--------VLP
Q-LVFLVLSLIHLCVQLYRMMDKGVFSYWRKPRNWLELSVVGVSLTYYAVSGHLAALAGD
VTDQFHRGLCQAFMDLTLMTSWNQRARWLQGILLFLLTLKCVYLPGIRNTKASCSS---M
THHSLP--SISVAVLAGALVLAALSHL-HRFLL-TMWALPP-GTFTDAFPG--LLFHFPR
-SQKDSLLGL---SKSDQRVMACYF--GILLTVSATLCFGMLRGFLMTLPRKR-KYFQSK
SLVRLKDVTAYMWEKALTFLRLETPKLEEAEMVENHNY-YLD-EFANLLDELLMKINGLS
DSLQLPLLEKTSN-----STGEARAEESPLVDIS-SKQATEVRPYFTGKEI---------
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----------------------------------MASSPGHSCFATS

PF02010 // ENSGT00700000104221_7_Domain_3 (888, 990)

SPHSLDAGAPSLA
FPADSLSDSYDQFVVTLTVSSAGRNSSEAQVFLSPRPDLVLRFV--HISWVSFKDVFVNW
NEELSLRAECDECGEGHTLSYSWDLFLVNATKRTRMEGKVTAAFILLTQA----------
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---MGPGKVQVWRSQPLTLAVTFESAIL

PF02010 // ENSGT00700000104221_7_Domain_3 (749, 863)

CDISQGLSYTWTFWNSQGWPVALPPTISTHRQ
TVTVPSYFLAPGNYTALARVRVVGSVVHSSYSVAVEVRARAPVSVISEGTHLFLSRA---
PSFPVVLTGSQSYDP-----DHP-------------------------------------
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