ENSGT00700000104221_0 : Linker Region Query Results

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HRQNNCYQFNRIHCSFEEAEH
YCQGQ-RGFLADIWKQEVQDLIRDFLEEGKKWWIGQNVMPLKKHQDEKYPAD----VAAH
GAPKPPSCTYLSRNVNRISSKEGKCFLRHYFICQTDG-IL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRPE------K
TKR---------------------------------------------------------
--GVEIARG---------------K-----------TPPGPGPL----------------
-----------------------STSCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEPSSQPLPVITQLTTPVSVTHAGQSMAETTSSPK
EAAHLNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VV
DETAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFVKP--------AQVNLINSLIY
LSEELLRIPF-LNNSSLDFKVHATVCPFHSFNDVIKAEEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQN
RSSESSVTLTSS-----IASLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSVGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNISME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VVTLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSPLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
VQASCLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDITKLVKLLSSLISSHLEGQS-CH-QQTERHLAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGLTQGHQPCDFLDAASQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKLISNG--LSKWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPGKVVFFTFLY----------SL-----MISRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIWKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPGLYGDYRGKSAVLK
PSHCK------------YGVQL--IFQIPCTTIYEKVKEGQL-VFSDMAVPVGIPRAC--
---------SVTSVH------PGPRGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------SLESFTSLQMS-KKGFAWSVI-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCRLKWQKWRFFTGRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYRDDQDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSQA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTGVLDE-LP-----------------

-----MFLKGGSWLWLYIRTSIILG----SELNSPAP--HGQNNCYQLNRFQCSFEEAEH
YCHVQ-RGFLAHIWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPAD----VAAN
GPPKPLSCTYLSRNFIRISSKGDECLLKYYFICQTGD-FL-------DGDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRHK------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGHL----------------
-----------------------PTTCHYP------------------------------
------------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CPPISPFPSVPP--------------------------
----------------SV-----------------------------------TSQV---
---------------------TSAASEPSSQPLPVITQLSTPVSVTHAGQSLAETTSSPK
EEAHPNTFTSYLQVSLQKASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFSKP--------AQVNLINSLIY
LSEELLRIPF-QNNNSLDFKVPPTVCPFHSFNNVTKAGEGSWLESKRHTEPV--------
--------------------------------ED-ILEMSLVEFGNIGEAFL-----EQN
QSPESSVTLTSA-----IATLLLSRQNISTLPLSSYTLGHPAPVRL--GFPSALALKELL
NKHPGVNV--------------------QITGLAFNPFKDLDNRNIVGSIGSVL------
---LSANRKLL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSLNMSTHQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYYITAVLSEREEGAQQTPSLVSVITAVTQCY-------YWEIHNQTW---SSA
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTIKLFLRVTNNPVGVSLLASL
LGFYVITVLWARKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTWTSLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--MRPFAVAWSELLVSIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
VQASYLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---WDITKLVKLLSSLVSSHLEGQG-CH-QQGERHWAR--VVPE
NHHHFCCY---LHRVLQRLKSHLGTLGLTQGHQSCDFLDAASQLQK-LQ--ELLESHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPISNG--LSKWLT-----SVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPVKVVFFTFLY----------SL-----MMSRMPRLNK-----------
-ENEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLE
PSHCK------------CGVQL--IFQIPCTKTYEKVDEGQL-AFCDNGHTCGRPKSLFP
G----LHLRRFSYIR------SPRPMVLIPTDELHKRLTSKNENGFSYIMR---GAFFTS
V----------RLESFTSLQMS-KKGCVWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCQLKQQKWRFFTGKRNI
LDTSIILISFILLGLDMKSISLHKKNMARYHDDQDRFISFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVIGRTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEAALIDTLLQKLSNLLGISWPQKT
SSEQ-----AA----T-------TAMGSDTEVLDE-LP-----------------

LIMSLPEWTWWILLWLCIGQNVLRG----GRLNY--QKQHRKSDCYQLNRVHCSFEGARN
YCHRQ-GGQLLTTWNQDIKNHLKDYLEKGKKWWIRSQYFLVK--KER---DVAGSM----
-AEKNNRCTYVIRNLDLVSSKVDLCSKEHFFICQGGNFIS-------NQFYSPLQRPLFK
KLNLMQMKNKVKGYSGGEISRLMGG--PAT-----FG-----------------------
------------------------------------------------------------
--------------FPKSNKL---------------------------------------
-------------YNE------YPST----------------------------------
------------------------------------------------------------
---------------------LSTTL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------CQEIS-NILISS-------A------------------
-----------------------------------------------------MPQ----
----------------TTEQILLAISPFARPPLPMTTMFNKPVS----EKPVSKVPATPR
EAPAVSISTTDPQISFQNISDQTLTEETD-------------------------------
------------------------------------------------------------
--GKELLCTPNLDLN-LVPKLQRACEILQQLTQFASPFSKT--------VQTNASSSLPN
LSEQLLKVQF-LSGNPFKLKAPATFCPFDSFNSETEASGENEVVIPQ--DF---------
------------------------------LKMEDMLQTSLLALGKIQETLL-----QDS
QPS---MIVTSS-----LATVMLKRQNISTLSSSSFTLHYPAPIHL--GFPSASALDNLL
RKNQSLNI--------------------QVTGLAFNPYEHFDKQNIVGSIGNVL------
---LTSDHESL---QIQDLLEEAEIIVWRDGSIE--------------------------
-----------------------TYPTTFNMSTDHFVITINITSLKESLIVLVEPENPLS
I--TLYLGFQYQPNITHFQ---LNITLPKEQ--LW-EKDEKYSWVLSPENL---------
-RHGTGTYHITAMVNESKKEPKQTSLGFSVTTATTQCF-------FWDLHNKTW---KSN
GCRVGPQSTITKTQCLCSHLTSVGSF FMALPRTVNIQ-DTVMLFHRVVHNPVGVALLASL
LGFYIIFIVWAWRKDREDRKKIKVTILADNSPSSQSY YL------IQVFTGYRRRAATTA
KV-----------------------ILILYGSEGRSDPHHL-SDPHKVVFEKGAQDVFLL
TTRSPLG-ELHSIRLWHDNSGTSPSW--------YVN------QVIVSDLATKKKW----
---------YFLCNCWLAVDLGDCRQDQVFTSVS-------KKELLSFRH--LFSSMIV-
--EKF-TQEHLWLSVVTCSPWNQVTRVQRLSCCMTILICNMVI-------NI-MFWKLNS
M-EDR---DMEDKVGPFAVTWSELLISIQTSSILFPINLIIGRIFPLIQRQEKIPPHFIP
IQASSISDTTLVSVTTQKITEEL-----KETVGFLHLK----------------------
-NSCSPSEWEGSNWNS---DSVPDLFKQLSSLIHSHLDRQGGRW-QQTGSLFAN--EVPE
NLHNLNHY---LLRVLERLQSQCRTLLTSPSTKSHDFLDSASQLQS-LR--ELVETHIL-
-------SKARDLCSDIT-SFPILDSEEEKPALSSY--LPKWSI-----YICWLLLGVTS
LVS-----AFF--TALYSLKLNKDQ--AT-------SWVI-----------------SMV
LSVLQNIFIIQPVKVTILTVFL----------SL-----LLTRISWHNK-----------
-EKEQQMRKIL-ALLARCPSLSSPGLRDENNPIYKVPAVTSPVIIPERTMKEKQLFQLAR
EIF-VQILFLVMLM-----ISAHSERTYNKFYLNQAIQKRINNPFEEIKRIKHFYQWT--
----------------------------------------NKTLIPNLYGKYRGKTHMVG
TGYQ---------------------------------EDQKN-YGVNW----TPLDLNST
-----NQESIWCYQN--EEVLGGYPIQ----------GQFAVYSE--MFTC---MMLYTI
RVSCL-IKTASKLLVGPPTEAS--------------THQHF--LKVMFFLAKRAFFNSIK
VNSLQITQ-THRSFIWFTASNVIYFLLLFYY-------IFIQVSRLRQQGWKYFTKKGNI
LDTSIILITFIMLVLQVKGVFLHKRVMDRYRHNKSRFISFHEVVQVAFALTYLLGFLVLL
TTIRLWSLLRLNPRLQIISTTLRRA---WDEVVGFLLIILILLTGYSI------------
----------AF--NILFGWSIADYKTFFNSAVTIVGLLMGIFDYHEVITLDPVLGSFLI
-ITSVILLVLVIVNLFVSAIMLTFRKERKSIM---KEAPLTEILLQKLSNLLGIRRPQKA
PEQRVP-------------------------------------------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HGQNNCYQFNRFHCSFEEADN
YCHGQ-RGFLAHIWNQEVQDLIRDFLEEGEKWWIGQNVMPLRKHQDEKYPAN----VAAH
GAPKPPSCTYLSRNFNRILSKEDKCFLRHYFICQTDG-VL-------DRDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YERPE------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPSGPGAL----------------
-----------------------SATCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEASSQPLPVITQLTMPVSVTRAGQSLAETTSSPK
EAAHVNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFFKP--------AQVNLINSLIY
LSEELLRIPF-LNSSSLDFKVPATVCPFNSFNDVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQD
QFPESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGTGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSS
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKAVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDIAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPH-FPP
IQASCLSDASAEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQLPWSS---CDITKLVKLLSSLISSHLEGQS-YH-QQAERHWAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGVTQGHQPCDFLDAVSRLQK-LQ--ELLETHLL-
-------PTEQEPSREVT-SFAILSSEEGRKPISNG--LSRWLT-----AACWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPGKVCAGREE-----------PL-----ELQKLG---------------
---------------KLRSLG-VRGQKQINNP--------------------NHFEKITK
NLK-LQILFLTLLM-----TAICSVKNSNRFYLHQAIRKTFSPRFSEIQLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PIHCK------------YGVQF--IFQIPCTTIYEKVEEGQL-VFSDMAVPVGIPRAC--
---------SVTSVH------PGPWGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCRLKRQKWRFFTGRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYRDDRDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVNSRTLSRV---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HRQNNCYQFNRIHCSFEEAEH
YCQGQ-RGFLAHIWNQEVQDLIQDFLEEGKKWWIGQNVMPLKKHQHEKYPAD----VATH
GAPKPPSCTYLSRNLNRISSKEGKCFLKHYFICQTDG-VL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRPE------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGPL----------------
-----------------------STTCHHP--------L---------------------
-----P------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CHPISLFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEPSSQPLPVITQLTTPVSVTRAGPSLAEATSSPK
EAAHLNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VV
DEIAGNFSRAVHGLQ-AHSKLQEACEFLQKLTALTPRFFKP--------AQVNLINSLIY
LSEELLRIPF-LNSSSLDFKVPATVCPFHSFNDVTKAEEGNWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQN
QSPESSVTLTSS-----VASLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVIGSVGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLI
M--TLYLGFQYQPNCTHFH---LNITLPKEK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VVTLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSPLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFR-----------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------FLLRR----------------------
-NTYLLSKCEQLPWSS---CDITKLVKLLSSLISSHLEGQS-CH-QQAERQWAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGLTQGHQPCDFLDAASQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGRKLISNG--LSKWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SFI
LSVLQNVFISQPGKVVFFTFLY----------SL-----MISRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDNNNPVYVAPAMNNPTKHPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIWKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PSHCK------------YGVQL--IFQIPCTMIYEKVKEGQL--------------SLFP
G----LHLRRFSYIC------SPRPMG----------LTSKNDSGFSYIMRINWSAFFTS
V----------RLESFTSLQMS-KKGFAWSVI-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCRLKQQKWRFFTGRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYRDDQDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLVILILLTGCAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVIDLDPVLGTFLI
-LTSIILMVLVVINLFVSAILMAFGKERKLLK---KEVALTDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

-----MFFRRRTWFWLYIRTSIFLG----RELNSPKQ--HGKINCYQLNRFYCSFGEAEN
YCRAQ-GGHLAYAWNQEVQDLIWNFLEEGKKWWIGQNLMLLRKYQEKNNPTA----VTAQ
WAPKPTDCTYMSRKSNWISSKVDLCSLEHYFICQADA-FS-------DQDADYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------HWRPK------K
AER---------------------------------------------------------
--EVAILRN---------------R-----------MTSGTTHL----------------
-----------------------STTCRQP------------------------------
------------------------------------------------------------
---------A--------------------------------------------------
--HA-NLSK-TL----------CHSVSPFSSVLP--------------------------
----------------KV-----------------------------------TQQG---
---------------------ISVTSVPTSQPLPVIAELTRPASVTHAEKALTEITSSPK
EDPHPNVFTTHLLASFQNASAQ--------------------------------------
----------------------------------------------------------VV
DEISGNFSKAIHGSQ-MHNKLQKACEALQKLTAFILGFSES--------VQXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXV--------
--------------------------------EN-ILKMSLLS---RGEAFV-----QQN
QFSESLVTLTSS-----VATLMLSSRNISTLPLSSYTLGYPAPVRL--GFPSAAALEKLL
NKHPGVTV--------------------QVTGLAFNPFRDFDDKHIVGSIGSVL------
---LSSSHGLL---QVQDLVEDIEITLWRNASME--------------------------
-----------------------THPTSLNVSTDRFTVTVNITSLEKSLIVCIEPESPLS
M--TLYLGFQYQPHHTYFH---LNITLPKNQ--VW-QKDEEYTWVLTPESL---------
-QHGTGIYYIAAVLXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXX---XXX
XXXVGPQSTVLRTQCLCNHLTYFGSE FFIVPRTVNVE-DTVKLFLRITNNPVGVSLLASL
LGFYMLILVWAWRKDQADMQKVKVTVLADNDPSSQ FHYL------IQVSTGYRRKASTTA
KV-----------------------VITLYGSEGQSEPHHL-CDSQKVVFERGGLDVFLL
STQSSLG-ELHSLRLWHDNSGVSPSW--------YVN------EVIVSDMAGKRKW----
---------HFLCDCWLAVDLGDCERDRVFIPVS-------KQELFSFRH--LFSSMIV-
--EKF-TQDNLWLSIATRQPWNQFTRVQRLTCCMTLLLCNMVI-------NV-MFWKMSS
TPAXX---XXX--XGPFAVTWSELLVSIQTAAILFPINLVIGRLFPLIQPQEPLPL-FPT
VLASCPSDAAFEPLSLTKVVEEL-----KGTVGFLLRR----------------------
-NTYLLSECEQSSWDS---YNINQLVKLLSSLVCSHVEHQG-YR-QQAGSCWAN--AVPE
NHRHVSCY---LLRVLQRLQSHLSTLGPTQVGLPCDFLDAASQLQK-LQ--ELLETCIL-
-------PTEQGPSREAT-SFPILSPEEGKKSTSNG--LPTWLT-----YICWLLLGVTS
LAA-----AFF--TVLYSLQLNKDQ--AT-------SWVI-----------------SMI
LSVLQNVFIIQPVKVIFLTLFF----------SL-----ILNRMPWLAR-----------
-EKEQQ--RIL-ALSAKCSSS-SPGSRDKKNPIYVAPAMNSPLKCPQRTLKEKKLFKLTG
DVL-VQIFFLILLM-----TAVNSTQNPSRFYFHQALQKSFSHRFSEIKLLKHFYTWA--
----------------------------------------SHILLPKLYGDDRGKAVLPR
GV-----------------------FSHTVTMTHTLV-KG---QLFQYGHTCGHPEDPLP
G----PHLSRFSYVS------SVRPMGLIPTDEFHKRLIN-NENVFTYRMK---SAFFTS
V----------RLDTLTSLQIS-KEDSTWSVV-SQV------------------------
----------------------IYYLLVCYY-------GFIQGRRLKQQRWKFFTMKKNI
LDMGIILTSFVILGLDMKLISLYKKNMAQYHYDRERFIRFSEAVTVNSAIIYLMSFLVLL
ATVQLWNLLHHNPRLRVIDRTLSKA---RDEVMGFLLVILILLTGYAI------------
----------AF--NLLFGGSISDYRTFISSAVTFVGLLMGISDHKEIIALAPVLGSFLI
-ISSVILLVLVIINLFVSAILMSFGKERKSFK---KEATLTDMLLQKLSSLLGIQRHRNT
CE-------TA----M-------TAMGTDTKVLKDELS-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------RATATSLPQSSFEVPEPRPVSV--TFPSSPALETLM
GPESYVQV--------------------RVASFALNPFRQLNGKPIRSVASVALA----A
EENETAEEQAL---HVQGLTEEIEIVLGGEADGGEASA----------------------
-----------------------MSSSMAGLGAGLFSLEVNITSLEDALLVSVRPQVPLQ
ITLNLLGPPGSKGNGSGSL---LNTTFPEGQPE-E-APETASVWVIPPESL---------
-RCGLGTYFISGEVTPVANA----SWNLSVGILSSGCY-------YWNSQDQAW---KTD
GCRVGPQSSLLRTQCLCNHLSFF GRFSLVLPHVIDLR-RTGLLLSRVGQNPAGVALLSSL
LLGYLAALIWARWRQRADARTVRVLALADNDPGAQF LYL------VQVFTGYRFGAGTSA
QA-----------------------VLTLYGAEGRSRPHLLQCSEASRGLERGGMDAFLL
ATRRPLG-NLHAARLWHNQTGSSPSW--------FVR------HLVVRDLNVRRRW----
---------YFLCNCWLASDMDDGQVDKVFVAAS-------QEELLSRRH--LFWAGLV-
--GKL-TQEHLWLSVLTCSVWSPFTRVQRLSCCLALLLCSMLI-------NI-MFWKEAP
RDDEP-----SSEAEPFVVTWKELMVSAQVAVLMVPVNLMVVHVFKLVHSPLG-PQHPPS
TRPPCPPLPASPVDPLTHLQQEL-----IETLGFLLKN------------ILWQHRE---
----------AGGFPG-ALQQVPELVASLCALVRSHLQALEDP----GGLL--QLLLIPE
RSRSLHSY---ICLVVKDLEAQLRNLDWCSLPKPYDYLHAADQLHK-LW--KNLEQHLPP
FV-----------------EVPLAPPPSLTFPDYSRWRLPSRWG-----FLCWGLVGTLS
LAS-----AFF--TVLYSLQMSRER--AS-------RWAL-----------------SVL
LSVLQNVLLMQPLKVLVLTALF----------SL-----MRKKQLWEDE-----------
-GQERRLHQALGALLAERQ-HYPPTFQHYTGPLPRPPALKSTARATDRTLREKKLYSWLW
EIV-GQLVFLAVLM-----TLSYIERSPEDFYLNAALQRRLTTGLAEVQTTTQFYFWA--
----------------------------------------SKTLVPAIYEDDESQGAGGD
PATVQGGLSSIFGV----------------------------------------------
-------------------------------------LGFALYPGSGYVAHLGTNASHAQ
RSGISPSLHPQSLSTNSSPRT----I-------HQD----AGVPSSAPLSTAGALQSKAE
LRLLRL-LASGRTLLHLALARAAFLVLLVGQ-------AFVQGRRMIWQKWGYFGNKRNL
LDTSALLVGLVAFGLQFKRAFLAYQILTQYRQNRRRFISLYEMAEVDAAITYLIAFLLAL
ATVKLWNLLRLNARMQIITQTLQAA---WEDLLGFLLVLLVLLAGYSM------------
----------AC--NLLFGWSILDYRTVLDSAVTIVGLLMGIFDYQEVVALDPVLGSLLV
-ISSIFSMVFVTINLLVSVLLIVFGRKMKAAKAS-KEESMLQLIQLKISLLFGI------
-------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------G--LPRWLA-----YLCWLLLGITS
LAS-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SLV
LSVLQNTFISQPVKVLKTTFHP----------RL-----VLRTVHK--------------
-----------------------------------------------RETLA-PLVPTHL
SAL-VQILFLTLLM-----TTIYSAKNSNRFYLHQAIQKSFSHHFSEIKLLKDFYPWA--
----------------------------------------ICTLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRNADTALFPRRVSPQEQMKASHQDQEDTEN-YGVNW----GPPDTNTT
-----QSDSIWHYQS--QETLCGYPIQ---G-----E--FATYSGGGYVVRLGRNSSTAL
RVL-------QHLKQNHWLDQHTKSLFVEFVVFNANVNLFCVVTLILECSKLGAFFTSVR
LDSLISLWTSKNSFAWPIISQVIYYLLVCYY-------TFIQGCRLKQQRWRFFSRKRNI
LDTSIILISFVTLGLDMKRTSLHKKNLARYRHNRDGYYAIIMLNNQTTLPCY--RFVS--
----FYEAVKMNSAV---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

-----MFFKGGSWLWLYIRTSIILG----SELNRPAP--HGQNNCYQLNRFHCSFEEAEH
YCHVQ-RGFLAHIWNKEVQDLIQAYLEEGKKWWIGQNVMPLKKHQDNKYPAD----VAAH
GPPKPPSCTYLSRNFHQISSKGDECLLRYYFICQTGD-FL-------DGDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRHK------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPAPGHV----------------
-----------------------PTTCHYP------------------------------
------------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CHPISPFPSVLP--------------------------
----------------SI-----------------------------------TSQV---
---------------------TSATSEPSSQPLPVITQLTTPVSVTHAGQSLAETTASPK
EEAHPNTFTSYLQMSLQNTSGQ--------------------------------------
----------------------------------------------------------VI
DEI-GNFSRADHGLQKAHNKLQEACEFLQKLRVLTPRFSKP--------VQVNLINSLIY
LSEELLRIPF-ENNNSLSFKVPATVCPFHSFNDATKAGERSWLESKSDTEQV--------
--------------------------------ED-ILEMSLVEFGNIGEAFL-----EQN
QSPESSVTLTSS-----IATLLLSRQNISTLPLSSYTLGHPAPVRL--GFPSVSALKKLL
NKHPGVTV--------------------QITGLAFNPFKDLDNRNIVGSIGSVL------
---LSANRKLL---QVHDLMEDIEIMLWRNVSVE--------------------------
-----------------------THPTSLNMSTHQLTITVNITSLEKSLIVSIDPDTPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-EHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCY-------YWEIHNQTW---SST
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTIELFLRVTNNPVGVSLLASL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTWSSLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KKELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--MGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
VQASCLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQLRQEN-----------------CLNPGGRG-C------SELRL--LVPE
NHHHFCCY---LRRVLQRLKSHLGTLGLTQGHQSCDFLDAASQLQK-LQ--ELLETHIL-
-------PMQQEPSREVT-SFAILSSEEGKKPISNA--LSKWLT-----SVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMT-----------------SII
LSVLQNVFIGQPVKVVFLTFLY----------SL-----MMSRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPIYVAPAMNSPTKRPERTLKNKKLFKLTG
DIL-VQILFLTLLM-----TAIYSAKNSNRFYLHQALQKTFSHQFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLE
PSHCK------------CGVQL--IFQIPHTKTYEKVEEGQL-A-------------LFS
G----LHLRRFSYIC------SPRPMALIPTDELHKRLTSKNENGFSYIMR---SAFFTS
V----------RLETFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQVCRLKRQKWRFFTGKRNI
LDTSIILISFIILGLDMKSISLQKKNMARYRDDQDRFISFYEAVKANSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSQA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYQTFFSSAVTVVGFLMGISHQEEVFALDPVLGTFLI
-LTSVTLMVLVVINLFISAILMAFGKERKSLK---KEAALIDTLLQKLSNLLAISQPQKT
SSEQ-----AA----V-------TAMGSDTEVLDE-LP-----------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPAP--HGQNNCYQLNRFQCSFEEAQH
YCHVQ-RGFLAHIWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPAD----VAAN
GPPKPLSCTYLSRNFIRISSKGDKCLLKYYFICQTGD-FL-------DGDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRHK------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGHL----------------
-----------------------PTTCHYP------------------------------
------------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CHPISQFPSVLS--------------------------
----------------SI-----------------------------------TSQV---
---------------------TSAASEPSSQPLPVITQLTMPVSVTHAGQSLAETTSSPK
EEGHPNTFTSYLQVSLQKASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-ALNKLQEACEFLQKLTALTPRFSKP--------AQVNLINSLIY
LSEELLRIPF-QNNNSLGFKVPPTVCPFHSLNNVTKAGEGSWLESKRHTEPV--------
--------------------------------ED-ILEMSLVEFGNIGEAFL-----EQN
QSPESSVTLTSA-----NATLLLSRQNISTLPLSSYTLGHPAPVRL--GFPSALALKELL
NKHPGVNV--------------------QITGLAFNPFKDLDNRNIVGSIGSVL------
---LSANRKLL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSLNMSTHQLTITVNVTSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLNPEHL---------
-QHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCY-------YWEIHNQTW---SSA
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTIKLFLRVTNNPVGVSLLASL
LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRSAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTWTSLG-NLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--MRPFAVAWSELLVSIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
IQASCLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---WDITKLVKLLSSLVSSHLEGQG-CH-QQGERHWAR--VVPE
NHHHFCCY---LHRVLQRLKSHLGTLGLTQGHQSCDFLDAASQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPISNG--LSKWLT-----SVCWLLLGFTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPVKVVFFTFLY----------SL-----MMSRMPRLNK-----------
-ENEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLE
PSHCK------------CGVQL--IFQIPRTKTYEKVDEGQL-AFCDNGHTCGRPKSLFP
G----LHLRRFSYIC------SPRPMVLIPTDELHERLTSKNENGFSYIMR---GAFFTS
L----------RLESFTSLQMS-KKGCVWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCQLKQQKWRFFTGKRNI
LDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEAALIDTLLQKLSNLLGISWPQKT
SSEQ-----AA----T-------TAVGSDTEVLDE-LP-----------------

-----MLFRGRTWVWLYIRTSIILG----SKLHSSEP--QEKNLCYQLNRFKCSFEKAEN
YCRAH-GGHLAHTWNKEVEDSLRNFLDEGKKWWVGKDID-LRKHHEENHPAD----VTAA
HPPKPVGCTHLSRNLNRISSEEDACLLRYYFICQTDS-FP-------DQDASHERNENNS
SL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------CQRPK------K
IER---------------------------------------------------------
--EVAVPRN---------------D-----------MKPGVVHH----------------
-----------------------DPPCHH-------------------------------
------------------------------------------------------------
------------------------------------------------------------
--PG-LPER-PL----------CPPIHPFPLIQP--------------------------
----------------KV-----------------------------------TRRI---
---------------------LSVASVLTSQPLPVTTELTRP--VAHAGKSLAEITSSPK
EDSQSDVFTS-IRASFQNASDQ--------------------------------------
------------------------------------------------------------
---------------------------------------------------VSVIDALTY
LSRQLLEIPF-QNSSSLGVRFPVTVCLFHSLNNVMEAGEEGRQNSEQDTEQV--------
--------------------------------ED-MLEMSLVALGNIQEAFL-----QQN
QFPASSVTLTSS-----IATLMLSSQNISTLPLSSYTLGHPAPVRL--CFPSASALEELL
NKHPGVHV--------------------QMAGLALNPFKDFGDGNIVGSVGSVK------
---LSSNRTLL---QVRDLMEDIEIILWRNVSME--------------------------
-----------------------THPISLNTSTDRFVITVNITSLEKTLIVSIEPESPLL
M--TLYLGFQCQPNHTHFH---LNITLPKDQ--VW-QKDEEYTWVLTPESL---------
-RYGTGTYCITAVWNGSQDGAQLTAPLVSVITAITQCY-------FWDSQNWTW---SSN
GCQVGPQSTILRTQCLCNHLTFF SSDFFIVPRTVHVE-DTIKLFLRVTSNPVGVSLLASL
LGFYMIIVVWAWRKDQADVQKVKVTVLADNDPDSQFR YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-WDPQKTVFERGGLDVFLL
TTRASLG-ELHGLRLWHDNSGVGPSW--------YVS------QVIVSDVAVERKW----
---------HFLCDCWLAADLGDCEQDRVFVPAS-------QRELFSFRH--TFSSMIV-
--EKF-TQDHLWLSVATRHPWNQFTRVQRLSCCVTLLLCDMVT-------NI-MFWKRSG
TSAKG---DEH-MLSPFAVTWSELLISVQTAVILFPINLVIEQLFPLIQPQETLPP-LPP
VQASCLSDASVQPLSLTKVVEEL-----KETVGFLLRR----------------------
-NPYLLSKCDQSSWSS---YDINKLVALLSSLIYSHLVGQG-CH-QQTEPPWAN--VVSE
NHRHFCCY---LLRVLQRLKSHVGTLRLTRLHQPCDSLDAASQLQK-LQ--ELLETHIL-
-------PTEEEPSREVT-SFPILSPAEGKNPIASG--LPRWLT-----YICWLLLGVTS
LTS-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SII
LSVLQNIFISQPVKVIVLTFFL----------SL-----VMNRVPWLNK-----------
-EKDRQTRRVL-ALSAKCSSP-LPSSKDKNNPIYVAPAMNSPMKHPERTLKEKKLFRLTG
DIL-VQILFLILLM-----TTVYSARNSNRFYLHQAIRKSFSHHFSEIKLLEDFYPWA--
----------------------------------------NRTLLPNLYGDYRGKSHSPG
AQPCK------------CGVQL--KLEKGQ--------WASSIWLQPCGHP----EGLFP
G----PHLSRFSYIC------SPRPMGMAPTAVSYKRLT---------------------
-------------------HKN-GNGFSYSTK-SNWSN----------------------
----------------------PWDSITCSKAGIRSNWKGVCDCVCITCRWRFFTRKRNS
LVTSIILISFTILGLDMKSISLHKKNMAQYRHDRDRFISFSEAVKVNSAAIHLTGFLVLL
ATVQLWNLLHRDARLQVIGRTLSKA---WGEVVGFLLIILILLTSYAT------------
----------AF--NLLFGWSISDYQTFVSSAMTVVGLLMGISHHKEVIALDPVLGSFLI
-LTSVILIVLVIINLFVSAILMAFRKERKSPK---REATLVDMLLQKFSSLLGIQLHQNP
SSKQ-----EA----T-------TAMANDTAVLEDELP-----------------

-----MFFKGGSWLWLYIRTSIILG----SKLNSPGP--HGQNNCYQFNRFHCSFEEAEN
YCHGQ-RGFLARIWNQEVEDLIRDFLEEREKWWIGQNVMPLRKHQGENYPAD----VAAH
GAPKPPSCTYLSRNLNRILSKEDKCFLRHYFICQTDG-VL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YERPE------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGAL----------------
-----------------------SATCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEASSQPLPVITQLTTPVSVTRAGQSLAETTSSPK
EAAHVNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFFKP--------AQVNLINSLIY
LSEELLRIPF-LNSSSLDFKVPATVCPFHSFNNVTKAGEGSWLESKSDTEQV--------
--------------------------------ED-ILEMSLAELGNIGKAFL-----EQD
QSAESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRMTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------SV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINVVIGRLFPLIEPQETLPL-FPP
VQASCLSDASAEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDVTKLVKLLSSLISSHLEGQS-CH-QQAERHWAR--VVPE
NHHHFCRY---LRRALQRLQSHLGTLGLARGHQPCDFLDAASQLQT-LQ--QLLETHIL-
-------PMEQEPSREVT-SFAILSSEEGKKPISNG--LSRWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLEMSKDQ--AT-------SWMI-----------------SII
LSVLQNVFISQPGKVVFFTFLH----------SL-----MMSRMPQLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIRKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PIHCK------------YGVQF--IFQIPCTTIYEKVEEGQL-VFSDKAVPVGIPRAF--
-----------TSVH------PGPWGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYS-------AFKLGCRLKRQKWRFFTGRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYHDDQDRFISFREAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDSLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

------MFWRRSWLWLYIRVGVLLG----HKLSN--PEQQGKNNCYQLNRLSCNFQEAET
YCHNQ-RGHLAHTWIPELQAFIQGSPNKETMWWVGRNLLLLNT-GFPGIQT-------VV
ADLKIGKCTSVVIRSNDVIPTKDQCSNKHHFICQADA-FP-------QHGASNGKNEHGK
NEHGPRR---PKTKRGAQTQTNVTSGNP--------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
IQPLPL-------HTLCFPIHPFSSVLPKATPQMII--TSPTRSSKVTSATPAL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------SSSSQVTSATPALSSSSQVTSATPALSSPSQVT-------------SAT
PALSS-PSQVTSATPALSSPSQVTSATPA-------------------------------
-----------LSSPPQVTSATPALSSSSQVTSATPALSSSSQVTSATPALSSSSQVTSA
TPALS-----------SSSQVTSATPVPNSPPWLVMTEVTRPESTITAGRSSADITSSPN
EDSHPEVISAHPQMSFQSTANQVSLETEDMPLPTEPSLQP--------------------
--------------------------------------------------DKIFSSQQVT
DQTAGKLIPEIPAVQ-AHSEFQKACDILQRVRNLPPTFPTS--------A----------
-----------QKNDSWNFKTPAVTCPLQDLGSAITTNQ---KILQQDPQQVSVLHAGAY
TAFGMAAGGSEILSYI--------WQRVSLKSVEDMLEMSLMALGEIHKAFC-----QQS
LSPELAVTLTSP-----VATLVLSSQNVSSLPLSTYTLGDPAPLRL--GFPSAEALKELL
SKHPGVNL--------------------QVTGLAFNPFETLDDRNIVGSIGNVL------
---LSSGYQSL---QVRDLIEDIEIMLWRNASME--------------------------
-----------------------TQPTSLNTSTDHFTITVNITSVEKTLIVTIEPESPLL
M--TLHLGFQDKPDHTLFY---LNTSLPRDQ--VW-QKDEEYTWVLTPKSL---------
-QYGIGTYYIMAVVNKSTEATQYTPIPVSVVTAVTQCY-------FWDQNNRTW---RSN
GCQVGLQSTILKTQCLCNHLTFF SSDFFIVPRTVDVE-NTIKLLLHVTKNPVGVSLLASL
LGFYILLVTWAWRKDRADLQKVKVTILADNDPSSAFH YL------IQVYTGYRRRAATTA
QV-----------------------VITLYGSEGHSEPHHL-CDPQKTVFERGALDVFLL
STGFWLG-DLHGLRLWHDNS------------------------VIVSDMTVKKKW----
---------HFQCNCWLAVDLGNCERDGVFTPAS-------RRQLSSFRH--LFSSTII-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCDMVI-------NV-MFWKTGG
ATAKR--------VGPFAVTWSEIAISVQTAIILFPIHLVFGRLFQLIHPPETLTP-LPP
IQATCPSGLAWESPSPTQVVTEL-----KETLGFLLRR----------------------
-NTYLLSECEQSWWCS---CDINELVKLFSGLIYSHLEDQG-CH-QQRESPRED--VVSE
NHHHFCRY---LLHVLQRLKSHLSALSAAQVQQPCDFSEAVSQLQN-LQ--ELLETQTL-
-------PREQGPCRYST-SFPILSPEEGKKSMLFC--LFKWLK-----YSCWLFLGVIS
LAS-----AFF--ITLYSLELNKDQ--AT-------SWVI-----------------SMM
LSVLQDIFVNQPIKVIFLTFLF----------SL-----MSNQMPWLNK-----------
-DKEQHAKRIV-ALWAKCSSS-APGLRDKNNPIYTAPVMTSSAKPPKGAWKK-HLFKLTG
GTL-VQILFLSLLM-----ATVYSARDSSQFLLHQAIRKRFSHRFSEIKLLEDFYPWA--
----------------------------------------KHSLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRIPKSMLFPA--SLHDQVNSHPQHQEDRGN-HGVGW----GPPDTNIT
-----ETDSIWHYQS--QELLGGYPTQ----------GEFATYSGGGYVVRLGRNSSAAA
RVL-------RHLEQRHWLDQSTKVLFVELTVFNANVNLLCAVTLILESNSVGTFFTSLQ
LDSLTSLQS-ERSFAWI-TSQVSYYLLVCYY-------TFIQGCRLKRQRWGFLTRKRNL
LDTSIILISFIILGLNMQRLSLLHKNMLQYRRDQDRFISFCEALKVNSAVTHLMGFLVLL
ATVQLWDLLRHNAQLQVISKTLNKA---WDEVVGFILTIMILLSSYAM------------
----------TF--NLLFGWSISDYRSFFSSTVTVVGLLMGISNHKEVIALYPILGSFLV
-LTGIILMGLVIINLFVSAILIVFGKERKALK---KEATLTDILLQKLSSLLGIHQHQKP
SSEKQVDNTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKLL

-----MFFRGRTWLWLCIRTGIILG----SELNRPEQ--HEKNHCYQLNMFHCTFEDAEN
YCSIQ-GGQLAFTWNQEIQDLLLDFLKEGSKWWIGKNLVPLGKQRQGKNN----------
-----------------------------------TAAFS-------DQDTSYERNGNNS
HS----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------HWRPK------K
TKR---------------------------------------------------------
--EVTILRN---------------K-----------VTSVATHL----------------
-----------------------STTCHQP------------------------------
------------------------------------------------------------
---------A--------------------------------------------------
--GA-NLSK-TL----------CHSISPFPAVPP--------------------------
----------------RV-----------------------------------TQQG---
---------------------VSAMPVPSSQ----TPELTRPASVTHAEKALVEVTSSSK
EDSHPDVFTPRPQESFQNTTDQ--------------------------------------
----------------------------------------------------------AI
DEITRNFSKVIRGLQ-AHDKLQQACEVLQNLAAFIPRFSES--------SQVSVMDSLVY
LNEQLLKT-----SSSLDSGMPVTVCLFXXALSNAVKAEASQ-RRSKHIEQV--------
--------------------------------EN-ILKMSLLSLGRIQEAFL-----PQN
RCSESAVTLTSS-----AATLMLSRQNISTLPRSSYTLGSPAPVRL--GFPSVSALEELL
NKHPGVSV--------------------QVTGLAFNPFRDFDNKKIVGSIGSVL------
---LSSNHKLL---QVHDLMEDFEITLWRNESME--------------------------
-----------------------THPTNLNVSTDHFIIMVNVTSLEKSLIVHVAPESPLL
M--TLYLGFQYQPNHTCSH---LNITLPKDK--VS-QKDEAYTWVLTPESL---------
-RFGVGTYYVTAVVNKSKAGAQRTPTLFWVVTAATQCY-------FWDSHSDTW---RSS
GCQVGPQSTLLRTQCLCNHLTYFGSE FFIVPRTVNIE-DTVELFLRVTRNPVGVSLLASL
LGFYMFTFVWAWRKDQTDMQKVKVTVLADNDPSSQ FHYL------IEVSTGYRRRAATTA
KV-----------------------VITLYGSEGRSKPHHL-CDSQKAVFERGGLDVFLL
GTPSSLG-ELHSLRLWHDNSGVSPSW--------YIN------QVIVSDIAGKRKW----
---------HFLCNCWLAMDLGDCERDRVFSPVS-------KKELFSFXX--XXXXXXX-
--XKF-T--DLWLSVATRHPWNQ-TRVQRLTCCVTLFLCNMVI-------NI-MFWKIND
TTAKR---DVQ--VGPLAVTWSELLISVQSAVILFPINVVIGQLFPLIQSQEPLPF-FPP
IQASCPSGASFEPLPLTEVAEEL-----KETVGFLLRR----------------------
-NTYLLSECEQSSWSS---YNINQLVKLFSSLICSHLEGQG-SH-QQAGPYWEN--AVPE
NHHHFCNY---LLRVLQKLQSHLRTLGPTQADQPCDFLDAVTQLQK-LQ--ELLETHTL-
-------PTERGPCREAN-SFPILNPEEGKQSISNS--PPRWLT-----YLCWLLLGTTS
LAA-----AFF--TVLYSLKLNKDQ--AT-------SWVI-----------------SLI
LSVLQNIFIIQPVKVIFLTLFF----------SL-----MLNRMPWLRK-----------
-EKGQQ--RIL-ALLAKCPSS-LPGSRDKNNPIYVAPAMNRPVKCPERALKEKKLLKLTG
DIL-VQILFLILLM-----TTVYSTQSSNRFYLHQAIQKSFSHGFSEIKLLKHFYTWA--
----------------------------------------NRILLPNLYGDYRGKNTVLG
S-SCK------------CGVQL--VFQTPTGTHTL--EEGPL---FHCGHPCG-PKGPLP
G----PRLSKSSYV-------PPRVMGLIPTDEPHKRLINKTENLFTYSME---SAFFTS
V----------KLDVLTSLQTS--KDFAWSII-SQV------------------------
----------------------IYYLLVCYY-------VFIQGRQLKQQRWRFFTRKRNI
LDMSIILISFVILGLDMKFISLHKENMAQYHCDPDRFINFYEAVKVNSAVIHLMGFLVLL
ATVQLWNLLRQNLRLQVIGRTLSKA---WDEVLGFLLVILILLSGYAI------------
----------AF--NLLFGWSISDYRTLFSSAVTVVGLLMGISHYKE-------------
------------INLFVSAILMSFGKERKSLK---KEAALTDMLLQKLSSLLGIQRPQNT
CKQ------IA----V-------TAIGIDNEVLKDGLS-----------------

-----MFFKGGSWLWLYIRTSIILG----SKLNSPGP--HGQNNCYQFNRFHCSFEEAEN
YCHGQ-RGFLARIWNQEVEDLIRDFLEEREKWWIGQNVMPLRKHQGENYPAD----VAAH
GAPKPPSCTYLSRNLNRILSKEDKCFLRHYFICQTDG-VL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YERPE------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGAL----------------
-----------------------SATCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEASSQPLPVITQLTTPVSVTRAGQSLAETTSSPK
EAAHVNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRLFKP--------AQVNLINSLIY
LSEELLRIPF-LNSSSLDFKVPATVCPFHSFNDVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQD
QSPESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------SV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINIVIGRLFPLIEPQETLPL-FPP
VQASCLSDASAEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDVTKLVKLLSSLISSHLEGQS-CH-QQAERHWAR--VVPE
NHHHFCRY---LHRALQRLQSHLGTLGLARGHQPCDFLDAASQLQT-LQ--QLLETHIL-
-------PMEQEPSREVT-SFAILSSEEGKKPISNG--LSRWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLEMSKDQ--AT-------SWMI-----------------SII
LSVLQNVFISQPGKVVFFTFLH----------SL-----MMSRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIRKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PIHCK------------YGVQF--IFQIPCTTIYEKVEEGQL-VFSDKAVPVGIPRAC--
---------SVTSVH------PGPWGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYY-------AFKLGCRLKRQKWRFFTGRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYHDDRDRFISFREAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HGQNNCYQFNRFHCSFEEAEN
YCHGQ-RGFLAHIWNQEVQDLIRDFLEEGEKWWIGQNVMPLRKHQDEKYPAD----VAAH
GAPKPPSCTYLSRNFNRILSKEDKCFLGHYFICQTDD-VL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YERPE------K
TKR---------------------------------------------------------
--RVAIARD---------------K-----------MPSGPGAL----------------
-----------------------SATCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSRV---
---------------------T-ATSEASSQPLPVITQLTTPVSVTRAGQSLAETTSSPK
EAAHVNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLAALTPRFFKP--------AQVNLINSIIY
LSEELLRISF-LNNSSLGFKVPATVCPFHSFNDVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQD
QSPESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQCQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQMPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRKAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIQPQETLPL-FPP
VQASCLSDASAEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDVTKLVKLLSSLISSHLEGQS-CH-QQAERHWAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGVTQGHQPCDFLDAVSRLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPVSNG--LSRWLT-----AACWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWTI-----------------SII
LSVLQNVFISQPGKVVFFTFLY----------SL-----MMSRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVPPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHEAIRKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PIHCK------------YGVQF--IFQIPCTTIYEKVEEGQL-VFSDMAIPVGIPGAC--
---------SVTSVH------PGPWGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYY-------AFKQGCRLKRQKWRFFTRRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYHDDRDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHKEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

-----MFFQRSTWPWLYMTVGVILG----HKQSKSEQ--DGKSQCFQFNRVHCSFEEAKA
YCHKQ-GGRLAQAWKQEIKAVIQSSLEEGSWWWVEQNPK-QRKHQGTSHPGN----GIPW
GVSKYGKCTSVFKSSEDMSSKQDQCAQKHYFICQAGRQDLFGLNVQADTDVHHVQEGEAA
GHFT--------S-------TARKQRERWMLVLTRFL-----SFIQSRTPVHQMVPPASV
A-----------------------------------------------------------
---------------PPRHYLGD------------------------VSWHADNQYKPSH
IVQRVSKKLFFLFNIMCDSN------HPSSIPPQTT---AVTPVTQVTSVIPVSRNPSQV
TLITTIPRR---------------PSQVTSFTPASSSPPQVTSVTPASRNPSQV------
-------TLVTTIPSSPPQVTSVTPAARSPPQVTSVTPA---------------------
-----ASSPPQVTLVTPVSRNPSQVMSVTPAASSPPQVMLVTPVSRNPSQVTLVTTISSS
PSQVTSVTPAASSPPQVMSVTPAASSPPQVTSVTPAASSPPQVM-------------LVT
PLSR-NPSQVTLVTTIPSSPSQVMSVTPPSSSPPQVTSVTPAAS-SPPQVTSVTPA----
-----------SSSPPQVTSVTPASSSPPQVMSVTPAASSPPQVTSVTPAASSPPQE---
---------------------MSDLPAPNSLPQSVITEPTRPVSAAPAGRPLVDITSRSK
EDSHPSVITTHPQASFQNASNQ--------------------------------------
----------------------------------------------------------VL
NETAGKFGGAIPGLQ-AHSRLKKACDILQKRRHFTPTFPAP--------DQ---------
------------ENSSWSSKTPARICLFSPLNSEAQGKKESQ-QPKQDTEKVGVLYVNSQ
-----------LCPET--------LSLSRYHTLEDMLETSLMALGEIQEAFL-----QQS
PFAESSVTLTSS-----VATLVFSSQNISTLPLSSYTLGDPAPVRL--GFPSAAALKALW
NNHLGINV--------------------QVTGLAFNPFKTLDNRSIAGSVGSVL------
---LSSGHETL---QVHDLMEDVEIMLWRNSSME--------------------------
-----------------------IHPTTFRTSTDRFIITMNVTSLEKSLIVTIDPESPLL
M--TLYLGFQYQPDHTHFH---LNITLPKDH--VW-QKDEEYTWVLTPESL---------
-QYGIGTYYITAMVNKRMEATLQTPVLVSVVTGITQCY-------FWDKYNRTW---NSN
GCQVGSQSTVWKTQCLCNHLTFF SSDFFIVPRTVDIE-DTVKLFLHVTNNPVGVSLLASL
LGFYMILVVWAWRKDQLDMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSDPHHL-CDPQKTVFERGALDVFLL
TTESSLG-ELHGLRLWHDNSGSSPSW--------FVS------QVVVSDMALKRKW----
---------HFLCNCWLAEDLGDCEHDGVFMPAT-------KRDLLSFRH--LFSSMII-
--EKF-TQDYLWLSVATRHPWNQLTRVKRLTCCMTLLLCDMVI-------NV-MFWKMGG
TAAKR---DEQ--IGPFTVTWSELLISIQTTVILLPVHLVIERLFLLIQPQEALPP-LPP
MQASCPSSAAGEPPSLTVVVEEL-----KETVGFLLRR----------------------
-NIRLLSECDLSLWSS---CNINKLVKLLSSLIYSHLEDQG-RY-QQAESHWAN--VVSE
THHHFCCY---LLKVLLRLKSHLGTLGLGQVHQPCNFSEAASQLQK-LQ--ELLETQIL-
-------PREQRPCRNTT-SFPILSPEEGKQPISTR--LLRWLT-----YISWLLLSVIS
LAS-----AFF--TALYSLELNKDQ--AA-------SWVI-----------------SMI
LSVLQDIFISQPVKVTFFTFLF----------SL-----MVSWMPWLHK-----------
-DKEQQTKKIV-ALWAKCSSS-LPGLRDKNNPIYTAPTMSSPAKRPKKAWTKKKLFKLTG
DIL-VQIIFLILLM-----TAVYSAKNSNKFFLHQAIWKSFSRSFSDIKLLEDFYPWA--
----------------------------------------NQTLLPNLYGDYRGFITDGN
NFLLGNVLLRQIRITNATFFPV--SFQNPVKPYYHHQEDMKN-YRVGW----GPPDTNST
-----KSDSIWHYQN--QESLGGNPI---QG-----EFAT--YSGGGYVVRLGRTSSTAT
RIL-------QHLEQMHWLDHCTKALFVEFVVFNANVNLFCV------------------
----------------------VTLILESNNVGMKISSLALTGCRLKRQKWKFLTRRRNI
LDTSIILISFSILGLDMKRISLHHKNMMQYHLDQDRFISFHETLKVSSAVTHLMGFLVLL
ATVQLWDLLRHNPRFQVINKTLSKA---WDEVMGFLLIILILLTSYAM------------
----------TF--NLLFGWSISDYQSFFSSAVNVIGLLMGISPHKEVIALYPVLGPLLI
-LTSVILMGLTIINLFISAILIAFGKERKSLK---KEAALTDMLLQKLSDLLGIQQHKNQ
PSPE-----NS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKLS

-----MFFKGRSWLWLYVRTSIILG----SELNSPER--GGQNNCYQLNSFHCSFEEAEH
YCHAQ-GGFLAHIRNQEVPDRIRDFLEEGKKWWIGRNVMPLKKHQDEKYPAD----TAAY
GDTKPSSCTYLSRNFSQISFKGDKCSLGHYFICQTGGVQG-------R------NLSSAT
SA----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------SWVPV------I
LLP---------------------------------------------------------
--QCLKYWF---------------L-----------FSIGAA-------HL---------
-----------------------STTCHHP------------------------------
------------------------------------------------------------
---------P--------------------------------------------------
--HA-HLSK-TL----------CHPISPFSSVLP--------------------------
----------------KI-----------------------------------TAQA---
---------------------TPVTSEPSSQPLPARTEPTSPASVTYAGQSRTETASSSE
EDAHPNSFTSHHPASLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIVGNFSRAVDGLQ-AHNKLQEACELLQKLTALTLRFSKP--------AQVHLINSLIY
LSEQFLRIPF-QNNSSLGFKVPVTVCLFDSFNNVIKAEEGSWQGSKHDPQQV--------
--------------------------------ED-MLEMSLVVLGNIGEAFL-----EQK
QPPESSVTLTSS-----IASLLLSRQNLSTLPLSSYMLGHPAPVRL--GFPSASALKELL
NKHPGVNV--------------------QVTGLAFNPFKDLDNRNIVGSIGSVL------
---LSANHKLL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSVNMSTDHFTITVNVTSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYYITAVLSESQEGAQQV----SVVTAVTQCY-------YWDSHNRTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFLVVPRTVNVE-DTIILFLRVTSNPVGVSLLASL
FGFYMITVVWAWRKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTHSSLG-ELHSLRLWHDNSGLSPSW--------YVT------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------QRELSSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNLFTRVQRLSCCMTLLLCNMVI-------SI-MFWKING
TTGKR---DEQ--MGTFAVAWSELLISIHTALILFPINLVIGQLFPLIQPRETVPL-FPP
IQVSCLLDASVESLSVTMVVEEL-----RETVQFLLRR----------------------
-HTYLLSECEQLSWSS---CNITKLVELLSSLLSSHLEGQG-CH-Q-AEHHWAH--VVPE
NHHHFCCY---LCRVLQRLKSHLGTLGLTQGHQTCDLLAAASHLQK-LQ--ELLETHML-
-------PTEQEPFREVT-SFAILSSEEGKRPISNG--LSKWLS-----SFCWLLLGLTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWMI-----------------SII
LSVLQNILISQPVKVVVFTFVH----------SL-----MMSRVPRLHK-----------
-EKEQQTKRIL-ALSAKCSSS-VPGSRDKNNPIYVAPTMNSPTKHPERTLKKKTLFKLTG
DIL-VQIFFLTLLM-----TTIYSAKNSNRFYLHQAIRRTFAHRFSEIKLLQDFYPWA--
----------------------------------------NHILLPNLYGDYRGKNAVLE
LSHCK------------CGIQL--IFQIPATKTHEKVRKVSW-LLL--------------
----------------------------IRPYLWRVQLYLFTQNGFSDIMRRNWSAFFTS
V----------RLESFTSLQMS-KKGFVWSVI-SQV------------------------
----------------------MYYLLICYY-------AFIQGCRLKRQKWRFFTRKTNI
LDTSIILISFIILGLDMKSISLHKKNMARYHHDRDRFISFYEAVKVNSATTHLVGFLVLL
ATVQLWNLLRHSPRLWVISRTLSQA---WDEVVGFLLIILILLTGYAI------------
----------AL--WFFD------------MAET------VLLLPSQVIALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---RQVALIDTLLLKLSNLLGIRQPQKT
SSEQ-----AA----T-------TSMGIDSEVLEDELP-----------------

------MFWRRSWLWLYIRVGVLLG----HKLSN--PEQQGKNNCYQLNRLSCNFQEAET
YCHNQ-RGHLAHTWIPELQAFIQGSPNKETMWWVGRNLLLLNT-GFPGIQT-------VV
ADLKIGKCTSVVIRSNDVIPTKDQCSNKHHFICQADA-FP-------QHGASNGKNEHGK
NEHGPRR---PKTKRGAQTQTNVTSVCDPDLPGGFWGSPKFPPLSTGVTGLRKSVPPGTV
FHGFSPPNSGTSSVDQAGLELRDPPASASASQVLGLKACATTTQPSLLSNEYFINSLRIP
YSVFWSYSFSSLPPVPPRSTLASLCTLNYIPFVLFFITHQVPFVLSTYSWEKHTLELGRP
IRPLPLHVFIFQSKTLCFPIHPFSSVLPKATPQMII--TSPTRSSKVTSATPAL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------SSSSQVTSATPALSSSSQVTSATPALSSSSQVT-------------SAT
------------------------------------------------------------
----------------------PALSSSSQVTSATPALSSSSQVTSATPALSSSSQVTSA
TPALS-----------SSSQVTSATPVPNSPPWLVMTEVTRPESTITAGRSSADITSSPN
EDSHPEVISAHPQMSFQSTANQ--------------------------------------
----------------------------------------------------------VT
DQTAGKLIPEIPAVQ-AHSEFQKACDILQRVRNLPPTFPTS--------A----------
-----------QKNDSWNFKTPAVTCPLQDLGSAITTNQ---KILQQDPQQVSVLHAGAY
TAFGMAAGGSEILSYI--------WQRVSLKSVEDMLEMSLMALGEIHKAFC-----QQS
LSPELAVTLTSP-----VATLVLSSQNVSSLPLSTYTLGDPAPLRL--GFPSAEALKELL
SKHPGVNL--------------------QVTGLAFNPFETLDDRNIVGSIGNVL------
---LSSGYQSL---QVRDLIEDIEIMLWRNASME--------------------------
-----------------------TQPTSLNTSTDHFTITVNITSVEKTLIVTIEPESPLL
M--TLHLGFQDKPDHTLFY---LNTSLPRDQ--VW-QKDEEYTWVLTPKSL---------
-QYGIGTYYIMAVVNKSTEATQYTPIPVSVVTAVTQCY-------FWDQNNRTW---RSN
GCQVGLQSTILKTQCLCNHLTFF SSDFFIVPRTVDVE-NTIKLLLHVTKNPVGVSLLASL
LGFYILLVTWAWRKDRADLQKVKVTILADNDPSSAFH YL------IQVYTGYRRRAATTA
QV-----------------------VITLYGSEGHSEPHHL-CDPQKTVFERGALDVFLL
STGFWLG-DLHGLRLWHDNS------------------------VIVSDMTVKKKW----
---------HFQCNCWLAVDLGNCERDGVFTPAS-------RRQLSSFRH--LFSSTII-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCDMVI-------NV-MFWKTGG
ATAKR--------VGPFAVTWSEIAISVQTAIILFPIHLVFGRLFQLIHPPETLTP-LPP
IQATCPSGLAWESPSPTQVVTEL-----KETLGFLLRR----------------------
-NTYLLSECEQSWWCS---CDINELVKLFSGLIYSHLEDQG-CH-QQRESPRED--VVSE
NHHHFCRY---LLHVLQRLKSHLSALSAAQVQQPCDFSEAVSQLQN-LQ--ELLETQTL-
-------PREQGPCRYST-SFPILSPEEGKKSMLFC--LFKWLK-----YSCWLFLGVIS
LAS-----AFF--ITLYSLELNKDQ--AT-------SWVI-----------------SMM
LSVLQDIFVNQPIKVIFLTFLF----------SL-----MSNQMPWLNK-----------
-DKEQHAKRIV-ALWAKCSSS-APGLRDKNNPIYTAPVMTSSAKPPKGAWKK-HLFKLTG
GTL-VQILFLSLLM-----ATVYSARDSSQFLLHQAIRKRFSHRFSEIKLLEDFYPWA--
----------------------------------------KHSLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRIPKSMLFPA--SLHDQVNSHPQHQEDRGN-HGVGW----GPPDTNIT
-----ETDSIWHYQS--QELLGGYPTQ----------GEFATYSGGGYVVRLGRNSSAAQ
QLG-------L-----------------------------------LYEKEKRTFFTSLQ
LDSLTSLQS-ERSFAWI-TSQVSYYLLVCYY-------TFIQGCRLKRQRWGFLTRKRNL
LDTSIILISFIILGLNMQRLSLLHKNMLQYRRDQDRFISFCEALKVNSAVTHLMGFLVLL
ATVQLWDLLRHNAQLQVISKTLNKA---WDEVVGFILTIMILLSSYAM------------
----------TF--NLLFGWSISDYRSFFSSTVTVVGLLMGISNHKEVIALYPILGSFLV
-LTGIILMGLVIINLFVSAILIVFGKERKALK---KEATLTDILLQKLSSLLGIHQHQKP
SSEKQVDNTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKLL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------PSASALNDLL
NKHPGINV--------------------QVMGLAFNPFKYLDQRNIVGSIGSVV------
---LTSNYQAL---QVSNLREDVELMLWRDDNSD--------------------------
-----------------------TSPTRFNMSTDSFVITVNITSLEESLIVQVEPENPLE
I--TLYLGFLFQPNSTHFI---LNITLPKDK-----FKDEEYTWVLSPASL---------
-QYGMGTYYVTVEIAQPKEFKLQTPMVFSVITAATQCC-------FWDHYNKTW---KSD
GCQVGPQSTITRTQCLCDHLTFFGST FFIVPRMVNVR-DTVQLFLGVTSNPVGVSLLASL
LGFYVIIVMWAWRRDKEDLQKAKLTILADNDPVAQ FCYL------IQVFTGYRRRAATTA
KV-----------------------ILTLYGTEGRSEPHHL-SDPQKTVFERGGLDVFLL
TTRSPLG-ELHSIRLWHDNSGPSPSW--------YVS------QVIVSDVAAKKKW----
---------HFLCNSWLAVDIGDCLHDRVFSSAS-------KKQLFSFRH--LYSSKII-
--EGF-TQDYLWLSVLTRCPWNPFSRVQRLSCCVTLLLCNMVI-------NI-MFWKERN
TGNTRVQQDMGKVLGPFAVTWSELFNSVQTTAILFPINLVIGRIFQLVRPKDLTPP-SIP
IQASPPLGTSSRVAPVTQIVEPIHLPTVKLTVGLRLET----------LHLLWALLLNAL
FLTDLFSKCLCQVWER---ENKHNLNFLLGS---SEIKSQGSCPGQQRGPHPA-------
-NALLSQC---LLKMLERLQSRLRSLDPSQSDSPNNLLPSANLLQK-LR--ERLERQIL-
-------SAERPP---------------------RY--LPYWFV-----YVCWFFVAATG
LLS-----AFF--TALYSLQLDRER--AT-------SWVV-----------------SMM
LSILQSIFIIQPVKIISLTLLL----------SL-----VLRRVLGNNK-----------
-EKEQEMKMIL-ALVVRCPSSALPGSRDESDPIYRPPAESSPARPKGRTSREKKLFKFTR
EVV-GFVIFLAMLI-----FLMHSEKSYNEFYFNQAIRKSFTHQFTKIRLLKHFYKWA--
----------------------------------------DRTLLPNLFGNYKGFITEGH
ALLLGTAIIRQIRLPAFASLPKRAFPQTPVPSYYYAQEDRED-YGTNW----SPLDQNST
-----IQESIWHYQS--EEELGRYPIQ----------GQFAIYSGGGYVVNLGQSSSDAR
SIL-------KHLKQGHWLDRRTKSLFVEFTVYNANVNLFCVVTLIMESSEVGAFSTSVE
LDTLHF--HSQKGFTQENAAQVIFCLLLLYY-------IFLQGRRLKQQRKSYFFKKSNI
LDLSIILISFIVVGLHMKRDFLHKRDMKRYFRDRSRNISFYQTIKVNSALTYVTGFLL-L
TIIRLWTLMRLSARLYVITRTLKRA---WDEVLGFLLIITILLAGYSI------------
----------TF--NLLFGWSISDYRTIFDSTVAIIGLLMGIFNYNEVIDLDPVLGSFLI
-ITIVVLMVLVVINLFISAILLIFRTERQLIGAL-KEAGLMEVLLQKLSSLLGIR-----
-------------------------------------------------------

-----MFFKGGSWLWLYIRTSIILG----SKLNSPGP--HGQNNCYQFNRFHCSFEEAEN
YCHGQ-RGFLARIWNQEVEDLIRDFLEEREKWWIGQNVMPLRKHQGENYPAD----VAAH
RAPKPPSCTYLSRNLNRIFSKEDKCFLRHYFICQTDG-VL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YERPE------K
AKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGAL----------------
-----------------------SATCHHP--------L---------------------
-----RSS----------------------------------------------------
----RKLLPL--------------------------------------------------
--TT-YISK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------ASQV---
---------------------T-ATSEASSQPLPVITQLTTPVSVTRAGQSLAETTSSPK
EAAHVNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFFKP--------AQVNLINSLIY
LSEELLRIPF-LNSSSLDFKVPATVCPFHSFNDVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQD
QSPESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------SV-MFWKINS
TTAKR---DEQ--LGL-LLSWSELLISIHTLSILFPINLVIGRLFPLIEPQETLPS-FLP
PGLLPLR-LLLLSFSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDVTKLVKLLSSLISSHLEGQS-CH-QQAKCHWAR--VVPE
NHHHFCRY---LRTSLQRLRSHLGTLGLARGRQPCDFLDAASQLQT-LQ--ELLETHIL-
-------PMEQEPSREVT-SFAILSSEEGKKPISNG--LSRWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLEMSKDQ--AT-------SWMI-----------------SVI
LSVLQNVFISQPGKVVFFTFLH----------SL-----MMSRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIRKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PIHCK------------YGVQF--IFQIPCTTIYEKVEEGQL-VFSDMAVPVGIPRAC--
---------SVTSVH------PGPWGR-FPADELHKRLTSKNDSGFSYIVR---SACFTS
V----------RLESFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYY-------AFKQGCRLKRQKWRFFTGRRNI
LGTSIILISFIILGLDMKSISLLRKNMARYHDDRDRFISFREAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILIAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDK-LP-----------------

-----MFFKGRSWLWLYVRTSIILG----SKLNSPER--RGQNNCYQLNSFHCSFEEAEH
YCHAQ-GGFLAHIRNQEVTDGSWDFLEEGKKWWIGQKVMPLKKHQDEKYPAD----IAAH
GDAKPPSCTYLSRNFSRISFKGDKCSLGHYFICQTVDAFL-------DRDARYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PWRPK------K
TKR---------------------------------------------------------
--EVEIPRN---------------R-----------MPPGAAHL----------------
-----------------------STTCHHP------------------------------
------------------------------------------------------------
---------P--------------------------------------------------
--HA-HLSK-TL----------CHPISPFSSVLP--------------------------
----------------KI-----------------------------------TTQV---
---------------------TPVTSEPSSQPLPARTEPTSPVSVTHAGQSQTEMASSPE
EDAHPHSFTSHPPASLQNASGQ--------------------------------------
----------------------------------------------------------VI
DETVGNFSRAIHGLQ-AHNKLQEACEVLQTLTALTPRFSKP--------AQVHLINSLIY
LSEQLLRIPF-QNNSSLGFKVPATLCLFHSFNNVIKAGEGSWQGSKHDPEQV--------
--------------------------------ED-MLEMSLVALGNIGEALL-----EQK
QPPESSVTLTSS-----IASLLLSRQNLSTLPLSSYTLGHPAPVRL--GFPSASALMELL
NKHPGVNV--------------------QVTGLAFNPFKDLDNRNVVGSIGSVL------
---LSANHKVL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSVNMSTDQFTITVNITSLEKSLIVSIDSDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDN--VW-QKDEEYTWVLTPERL---------
-QHGIGTYYVTAVLSESQEGAQQMPSLVSVITAVTQCY-------YWDSHNRTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFLVVPRTVNVE-DTIILFLRVTSNPVGVSLLASL
LGFYVITVVWAWRKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKRVFERGGLDVFLL
TTHSSLG-ELHSLRLWHDNSGLSPSW--------YVT------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCEIDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQEYLWLSVATRHPWNLFTRVQRLSCCLTLLLCNMVI-------SI-MFWKING
TTGKR---DEQ--MGTFAVAWSELLISIHTAVILFPINLVIGRLFPLIQPQETVPL-FPP
VQVSCLLDASVEPLSVTMVVEEL-----RETVRFLLRR----------------------
-HTYLLSECEQPSWNS---CNITKLVELLSSLLSSHLEGQG-GH-QQAERHRAC--VVPE
NHHHFCCY---LCRVLQRLKSHLGTLGLTQGHQTCDLLAAASHLQK-LQ--ELLETHML-
-------PTEQESFREVT-SFAILSSEKGKRPLSNG--LSKWLS-----LFCWFLLGLTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWMI-----------------SVI
LSVLQNVLISQPVKVVVFTFFH----------SV-----MMSRVPRLHK-----------
-EEEQQTRRIL-ALLAKCSSS-VPGSRDKNNPVYVAPTMNSPTKRPERTLEKKKLFKLTG
DIL-VQIFFLTLLM-----TTIYSAKNSNRFYLHRAIQRTFAHRFSEIKLLQDFYPWA--
----------------------------------------NHILLPNLYGDYRGKNAVLE
LSHCK------------CGIQL--IFQIPATKTHEKVRKVSW-LLL--------------
----------------------------IRPYLWN-------ENGFSDIMRRNWSAFFTS
V----------RLESFTSLQMS-KKGFVWSVI-SQV------------------------
----------------------IYYLLICYY-------AFIQGCRLKRQKWRFFTRKRNI
LDTSIILISFIILGLDMKSISLHKKNMARYHHDRDRFISFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLWVISRTLSRA---WDEVLGFLLIILILLTGYAI------------
----------AF--NLLFGCNVSDYQTFFSSAVTIVGLLTGISHQEEVIALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---RQVALIDMLLQKLSSLLGIRQPQKT
SSEQ-----AA----T-------TSMGIDTEVLEDELP-----------------

------LFPRRSWLWLYIRVGVLLG----HEPSNVFPEPPGKNSCYRLHRLLCSFEEAET
YCRGSPGGRLAHTWNPALQTFFQSSLRNEIVWWVGENLMLPRKRQETSHPG-------AV
IGFRAPKCPSVVTRSNESFSTRDECSNRHHFICQTEA-FP-------QHGASRGRNEHSL
GRLR--------KNRGVRRQTHMPSGDVP---------------------------PPAT
CHQ---------------------------------------------------------
------------------------------------------------------------
------HAPTDLPKPLCFPILPFFSLPSKVIPQMII--TSPTRSSQVTSATPAPSSPPQV
TSATPTSNSSL---------------QVTSTT----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------PA-------------------------------
-----------PSSSPQVTSATPTSNSSLQVTSATPTSNSSLQVTSATPTSNSSLQVTSA
TSAPS-----------SPPRVTSATPVPSSPPWRVMTEVTRPESTIPAGRSLADITSSAK
EDTSPAVISTHPQRSFPSPAYQ--------------------------------------
----------------------------------------------------------VT
DQTAGNLILDIPAFQ-ADSEFQKACDILQRLRNSPPTSPTP--------A----------
-----------QQNDSRNLKTPAVVCPLQPLGSTITTKKGSQQILQQDTEL-AEHPTDAY
TAFGIGAGGSEILSDI--------WLQSAF-EVADMLEMSLMALGEIHKAFC-----QQS
LSPESAVTLTSP-----DAALLLSSQNVSSLPLSTYTLGDPAPLRL--GFPSAEALKELL
NKHPGVNL--------------------QVTGLAFNPFETSDDKNIVGSIGNVL------
---LSSGYHSL---QVHDLIEDIEIVLWRNASME--------------------------
-----------------------TQPTNLNTSTDRFTVTVNITSVEKTLIVTIEPESPLL
M--TLYLGFQDEPDHTHFY---LNVSLPRDQ--VW-QKDEEYTWVLTPESL---------
-QYGTGTYYIMAVVNKSTEAMQCTPILVSVVTAVTQCY-------FWDQNNRTW---KSD
GCQAGPQSTIWKTQCLCNHLTFF SSDFFILPRTVDVE-NTIKLLLRVTNNPVGVSLLASL
LGFYSLLVTWAWRKDRADMQKVKVTVLADNDPSSAFH YL------IQVYTGYRRRAATTA
QV-----------------------VITLYGSEGHSEPHHL-CDPQKAVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGDNPSW--------YVS------QVIVSDMTVKKKW----
---------HFQCNCWLAVDLGNCERDRVFTPAS-------RKELSSFRH--LFSSTII-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCDMVI-------NV-MFWKMGG
TTAKR---------GPFAVTWSEILISVQTAIILFPIHLVFGRLFQLIHPPEPLPR-LPP
TQAAYPLGLAYESPSPTQVVTEL-----KETVGFLLRR----------------------
-NTHLLSECEQSSWSS---CDINKLVTLFSSLIYSHLEDQG-RH-QQTESRWED--VVSE
SHHHFCRY---LLQVLQRLKSHLSELSAAPVHQPCDFSEAVSQLQK-LQ--EFLETQLL-
-------PRERGPCRQST-SFPILSPEERKTPVSFG--LFKWLK-----YICWLLLGVIS
LAS-----AFF--VTLYSLELNKDQ--AT-------SWVI-----------------SMM
LSVLQDIFVSQPLKVTFLTFLF----------SL-----TANQMPWLNR-----------
-DKEQHAKRIV-ALWAKCSSS-APGLRDKNNPIYTAPAMTSSAKHPKTAWKK-QLFKLTG
GPL-VQILFLSLLM-----ATVYSARDSSQFFLHQAIWKRFSHRLSEIKLLEDFYPWA--
----------------------------------------NHTLLPSLYGDYRGFITDGN
SFLLGNVLLRQIRIPNDTLLPV--SLHEQVTSHPQHQEDREN-YGVGW----GSPDTNIT
-----ETDSIWHYQN--QESLGGYPTQ----------GEFATYSGGGYIVRLGRNSSAAA
RVL-------QHLEQRRWLDHCTKALLVELTVFNANVNLLCAVTLLLESNSVGTFFTSLR
LD-LTSLRSSERGFAWI-ISQVTYYLLVCYY-------AFKQGCRLKRQGWGFLTRKRNL
LDTSIILISFSILGLNMQRRSLLHENMLQYRRDRDRFISFSEALKVNAAVTHLMGFLVLL
VTVQLWDLLRQNAQLQVISKTLNKA---WDEVVGFLLIIIILLSSYAM------------
----------TF--NLLFGWSISDYQSFFSSTVTVVGLLTGISNHKEVIALYPVLGSFLV
-LTSIILMGLVIINLFVSAILIVFGKERKALE---KEATLTDMLLQKLSSLLGIRKHQNP
ASEKPADNTGS----SNLRERSSKSMSSDAEVLAPAEAVGSVSGTDGNSGSTKLL

-----MLFRGRTWVWLYIRTSIILG----SELGSPELPERKKNLCYQFNRFNCSFEEAEN
YCRAH-QGQLAHTWNKGVEGFLSHILDEGKKWWIRENFK-ASKHRGENHPDV----AGPA
HPPKPSGCTYLSEDLRGISSKKDKCSRKYYFICQTDF-IP-------DQNASHERNEGNF
PL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------CQRPK------K
TEG---------------------------------------------------------
--DVAIPRN---------------D-----------MNPGNPGH----------------
-----------------------LPAAPRS------------------------------
------------------------------------------------------------
------------------------------------------------------------
--SQ-YAKS-PL----------CYSINPFPLRQP--------------------------
----------------NV-----------------------------------TPGG---
---------------------SSVGSVTTSQPLPVTTELTRP--VTHAGKVLAEMTSSPK
EDSQTDVFTY-IQASFQNASDQ--------------------------------------
----------------------------------------------------------FI
NGIAEKFSRAVHGLQ-AHDKLQEACKILRTLTAFAPQLSKP--------AQVSVINSLIY
LSEQLLKMPF-QNSSSRGFKNSVTVSLFHSVNNVMEAGEEVWQNSEQEAEQV--------
--------------------------------ED-MLEMSLAALRNIQEAFL-----QQN
HFLASPLTVTSS-----VSTLMLSSQNISTLPLSSYTLGHPAPMRL--CFPSAWALEKLL
NKCPRVNV--------------------QVAGLALNPFKHFGDGNIVGSIGSVK------
---LSYNNTLL---QVQDLMEDIEIILWRNVSVE--------------------------
-----------------------THPISLNTSTDRFAITVNVTSSEKALIVSIEPESPLL
M--TLYLGYQYQPNHTHFH---LNITLPKDQ--VW-QKDEEYTWVLTQESL---------
-RYGPGTYYITATWNGSQDGAQLTPPLVSVVTASTQCY-------FWDSQNRTW---RSN
GCQVGPRSTILRTQCFCNHLTFF SSDFVVVPRTVHVE-DTIKLFLRVTSNPVGVSLLASL
FGFYLIIVVWAWRKDQADVQKVKVTVLADNDPDCQFR YL------VQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-WDPQKMVFERGGLDVFLL
TTRSSLG-QLHGLRLWHDNSGASPSW--------YVS------QVIVSDVAVKRKW----
---------HFLCNCWLAVDIGDCEQDRVFVPAS-------ERELLSFRYQ-PISSVIV-
--EKF-TQDYLWLSVAKLGHQRLSLGCATCSCCNT-----RSQ-------RR-MFWKGPP
P---A---RER-PRPPFALTWSELLVSVQTAVILFPVNLVPRET--------LPPP-LPS
SQASCLSDASIQPLSLTKVVEEL-----KETVGFLLRR----------------------
-NPYLLSECDQSSWSS---HDINKLATLLSSLIYSHLEGQG-CH-Q-AEPPWANGKVAPE
NHRHFCCY---LLRVLQRLKCHIGTLGLTQGHQPWDSLDTASQLQK-LQ--ELLKTHTL-
-------PSEEEPSREIT-SFPMLSSGEGKNPISGS--LPTWLP-----YICWLLLGVTS
LAS-----AFF--TALYSLELNRDQ--AT-------SWVV-----------------SII
LSVLQNIFLSQPVKVIVLTFLL----------SL-----MTNRMPWLNK-----------
-EKEQQTRRVL-ALLAKCSSP-LPGLRDKNNPITVAPAMNSPTKHPERTLKGKRLFRLTG
DIL-VQILFLILLM-----TTVYSARNSNRFYLRQAIWKSFSQHFSEIKLLEDFYPWA--
----------------------------------------NRTLLPNLYGDYRGKSHNPG
ALVIQ-------------------------------------MWSNENGFRYSTESAFFT
S----VRLDSL------------------PS-------L---------------------
-------------------QTS-KKGFAWSVI-AQV------------------------
----------------------VYYLLVCYY-------AFVQGRRLKRQRWKFFSRKRNI
LVTGIILISFTILGLDVKSISLHKKYMAQYRRDRDRFVSFYEAVKVNSAAIHLAGFLVLL
ATVQLWNLLHPNARLQVIGRTLSKA---WGEVVGFLLIILILLTSYAI------------
----------AF--NLLFGWSISDYQTFVSSAMTVVGLLMGISHHKEVIALDPVLGSFLI
-LTSVILIVLVIINLFVSAILMAFRKERKSPK---KEATVVDMLLQKFSSLLGIQRYQNP
SSKQ-----EA----M-------TAMGKDIEVVENELP-----------------

-----MLPTPRSWLWFCIRTALVLG-----------N--QWKRECYQLYRSQATLEGAQN
YCRNH-DGYLPNDWNQNIPDFIQDSLEEGTKWWIRQKSMPMSEPQEKRPXXX----XXXX
XXXXXXXXXXXX----------------------XXX-XX-------XXXXXXXXXXXXX
XXXX--------XXXX----------------X---------------------------
X-----------------------------------------------------------
------------------------------------------------XXXXX-X----X
XXX-----------XXXXX---------------XX------------------------
--XXXXXXX---------------X-XX--------XXXXXXX-----------------
-------------------LTRPSPGGHCP------------------------------
------------------------------------------------------------
------------------------------------------------------------
------PLQ---------LKILCQPISPSPVMEI--------------------------
-----------------------------------------------------TPQVTAG
-----------------------------TSP---HPELTSSGAIAGTGQSTARRPPRPK
TPSKE------GCATFTSTLDQ--------------------------------------
----------------------------------------------------------IT
NNTARNVSRAAQGVP-APRELQEACQVLQGLRTLGSRVFQP--------AQARIIHALID
LHKQLLADPDPFQNSSLDVSMPVTSCPFQQE--MREAGEGSWQGHGQL------------
--------------------------------VEDVLELSLMALGKLQQAFV-----QRN
QVSGSSVTVTSS-----SAVVMLSSQNASTLPLSSFAVGGPAPVRL--GFPSATALEELL
KRHPGVSV--------------------QVTGLAFNPFEDLDDKNIVGSVGTVL------
---LSSDHKLL---HVHGLMEDIEIMLWRNSSLD--------------------------
-----------------------THPTSLNLSTSRFVIALNVTSADKTLLVSLQPEAPLS
V--TLHLGFQQPPEPTSSP---HNITLPRDQ--VW-QKDEEYTWVLTPESL---------
-QYGTGTYYITAVLEGDT------QTPVSVVTAVTQCY-------FWNSHERAW---KSN
GCQVGARSTVRRTQCLCNHLTFFGSD FFILPRTVNVE-DTVQLFLRVSSNPVGVSLLASL
LAFYATLALWAWRKDQADAQKVKVTMLADSDPGGR FHYL------IQVYTGYRRRAATTA
KV-----------------------VLTLYGSEGRSEPHHL-ADPHKPVFERGALDVFLL
ATRSPLG-QLHSLRLWHDNSGASPAW--------YVT------RVVVSDLTLQRKW----
---------HFLCHCWLAVDLGDCERDRIFLPAS-------HGELLSFRH--LFPSVMV-
--EKF-TQDYLWLSVATRHPWSPFTRVQRLSCCVTLLLCNMLI-------NV-MFWKANA
AVAGQ-----EAPMGPLAVTWSELRISLQTAVILFPINLVVGRLFLLTQPQEALPP-IPQ
AW-ACLSDAXXXXXXXXXXXXXX-----XXXXXXXXXX----------------------
-XXXXXXXXXXXX--X---XXXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXAPE
NQRLLSCY---LLGVVERLQSRLGALSPSQVPSPGDVQEAASQLRR-LR--DLLRTQTV-
-------PVEQDVSREVT-CFPLLSPEAERNSSIAG--WCQRLS-----YASWTLLSAAG
LAA-----AFF--TALYSLDLNRDQ--AS-------SWVV-----------------SMM
LSLLQNICISQPVKVVILTFGL----------SL-----LMKRVPWLNR-----------
-ESEQR--RIL-ALAAKCSSS-PPASRDRNNPVYVAPTMHGPARCPAGAVGRRRLCRIAA
GIM-VQTLFLVLLM-----TRTYSAQNSNRFYLHQAIRKSLAPGFAKIRLLEEFYPWA--
----------------------------------------RHSLLPHLFGDGRGEAL---
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------FSSVS
VDSLPALQASQMGIGWDVISQVLYHLLVCYY-------TFVQGWRLKRQGWRFLTQKRNV
LDTSVVLISFVILALDMTRISLHQKHMAQHRQDPDGFVSFSEALSVNCATTYLVGILVLL
ATLQLWHLLHHDARLQVISRTLSKA---WDEVTGFLLIILVLLTGYAI------------
----------AF--NLLFGWSISNYRTFINSAVTVVGLLVGVSHHKEVIALDPVLGGFLT
-LTSVVLMVLVIINLFVSAILMAFGRERKSLK---RETTLIDVLLHKLSGLLGIRRHAAP
PPAAAGVPEGK----PP--------------------------------------

-----MLWQRRSWLWLYIRIGVLLGVILGHEPSI--PEQHGKNSCYQFNRFFCDFQEADK
YCQAQ-RGRLAHTWNPKLRGWLKSVPKEETVWWVRGNLKLPGKHLGINQTGG----ADIL
KNQKPGECPTVVTHSNAVFSRWDQCIRKHHFICQA-------------------------
-------------------------GDGPPLAM---------------------------
CHQPAP------------------------------------------------------
------------------------------------------------------------
---------PELVTSN--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------TPASSSPPNMTSDTPASSSPPQVT-------------SDT
PGFS-SPPQVTSDISASSSPPNMTSDTPASSSPPQVTSETPASS-SPPQVTSDISAS-SS
PPNMTSDTPA-SSSPPQVTSDTPASSSPPQVTSDISASSSPPNMTSDTPASSRPPNMTSD
TPASS-----------XPPQVTSDTPG-----------FSRPESTIPAGRSLADITSKAQ
EDSSPGVISTHPQMSFQNSTNQ--------------------------------------
----------------------------------------------------------DT
DETAGELVPTIPDSQ-AHSGLQKACAILQRLRDFLPTSSTS--------A----------
-----------QKNNSWSSQTPIVSCPFQPLGSLITTKGDSRQMVQQDTE----------
-------------------------------QVEDMLETSLMALGEIHRAFC-----QQS
LCPQSAVTLASP-----SATLMLSSQNVSTLPLSTYTLGEPAPLRL--GFPSAEALKELL
NKHPGVNL--------------------QVTGLAFNPFETSDDRNIVGSIGNVQ------
---LSSAYQSI---RVHDLIEDIEIVLWRNASME--------------------------
-----------------------TQPTSLNTSTDHFTISVNITSLEKTLIVTIEPESPLL
M--TLHLGFQDQPAHTHFY---LNISLPRGQ--VW-QKDEEYTWVLTPENL---------
-WYGTGTYYIMVVENTSTETAQRTPVLVSVVTAVTQCY-------FWDRYNRTW---KSD
GCQVGPKSTILKTQCLCDHLTF FGSDFFIVPRMVDVE-NTIKLLLHVTDNPVGVSLLASL
LGFYILLAMWAWRKDRADMQKVKVTILADNVPSAASH YL------IQVYTGYRRRAATTA
KV-----------------------IITLYGSEGHSEPHHL-CDPEKTVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGDSPSW--------YVS------QVIVSDVTARKKW----
---------HFQCDCWLAVDLGNCERDRVFTPAS-------RSELSSFRH--LFSSTIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVI-------NV-MFWKMGG
TTAKR---GTE-QVGPLAVTLSELLISIQTTIILFPVHLIFGRLFQLIHPPEALPQ-LPL
IQAAWPSTLVCESPSLTQVVKEL-----KETVGFLLRR----------------------
-NTQLLSECEQSSWSS---CDINKLAELLSRLIYSHLEGEG-CH-QQTESHWED--AVSE
NHYHFCRY---LLQLLRGLKAHLDALGATQDHQPCDFSKAVGQLQT-LQ--ELLETQTL-
-------PRGPGPGRHST-SFPILSPEEGKKPMSFC--LFRWLK-----YSCWLFLGVIS
LAS-----AFF--IMLYSLELDKDQ--AT-------SWVI-----------------SMM
LSVLQDIFISQPIKVIFLTLLF----------SL-----MANHMPWLNK-----------
-DKEQHTRRIL-ALWAKCPSS-APGLRDKNNPIYTAPAMNNLAKQTKKAWKK-QFFKLTG
GTL-VQILFLSLLM-----TTVYSAKDSSRFFLHQAIWKRFSHHFSEIKTVEDFYPWA--
----------------------------------------NRTLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRIPNAILFPG--SLHKQMKSSPQHQEDREN-YGAGW----VPPDTNIT
-----KADSIWHYQS--QASLGGYPMQ----------GELATYSGGGYVVRLGRNHSAAT
RIL-------QHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILESSGVGTFLPTLR
LDSLTSLQSSERGFAWI-VSQVVYYLLVCYY-------AFIQGCRLKRQRLAFFTSKRNL
LDTSIVLISFSILGLSTQSLSLLHNKMRQYHCDRDRFISFCEALRVNSAVTHLRGFLLLF
ATVRVWDLLRHHAQLQVINKTLSKA---WDEVLGFILIIVVLLSSYAM------------
----------TS--NLLFGWSISDYQSFFRSIVTVVGLLMGISKHKEVIALYPILGSFLV
-LSSIILMGLVIINLFVSAILIVFGKERKVCE---KEATLTDMLLQKLSSLLGIRQHQNP
S-EEHADHTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKVL

-----MFFKGRTWLWLYITTGFVLG----SELHGPEQ--RGGNNCFQLNSFRCSFEGAER
YCHAQ-GGHLAFTWNQEVQDLLWDFLEK-EKWWVGGNLTLPRKHQEKNHPAD----VTAR
PATKPARCVYLTRSHNQTSSKEGSCSAKHYFICQAD-SFS-------DQDANCERNGNNS
HS----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------RGKLK------R
TKK---------------------------------------------------------
--EVIRPRS---------------K-----------VTSGDTHL----------------
-----------------------STTCHQP------------------------------
------------------------------------------------------------
---------A--------------------------------------------------
--QA-NMSK-TL----------CHHLSPFPSVPP--------------------------
----------------EV-----------------------------------TPQG---
---------------------VSVTPAPTSKPLPLTPELPGPGSVTHAGKALEEITSSPK
EDSHPSVFTSHPQVPFQNAPDQ--------------------------------------
----------------------------------------------------------VI
DEITGNFSKAVLGLR-THNKLQKACEILEGLAAFIPGFSES--------AQVRVINTLTD
LNEQLLQSPL-LNSNNPGSRTPVTVCLFHSLNNVMKAGEASRPRHGHSVEQV--------
--------------------------------EN-MLKMSLLSLGRIQETFL-----QQN
RCAEPEVTLTSS-----TAALMLSRQNISTLPLSSYTLGDPAPVRL--GFPSASALEELL
KKHPGVDV--------------------QVTGLAFNPFRDFDKKKIVGSVGSVL------
---LSSNHKLL---QVHDLMEDIEIMLWRNASME--------------------------
-----------------------THPTSLNMSTDHFTITVNVTSLEKSLIVCVEPEGPLS
L--TLYLGFQHQPNHTPHQPNHTHFRLPKER--VS-QKDEEYTWVLRPEKL---------
-RYGVGTYYITAVLDKSKEGARQTPTLLSVVTAVTQCY-------FWDSLNSMW---KSS
GCQVGLQSTLVRTQCLCNHLTYFGS DFFLVPRMVNVE-DVAELFLRVTSNPVGVSLLASL
VGIYMLIFVWAWRKDQADAQKVKVTILADNDPSSQ FHYL------IAVSTGYRRRAATTA
SV-----------------------VITLYGSEGRSQPHHL-CDSQKAVFERGGLDVFLL
GTPSSLG-ELHSLRLWHDNSGASPAW--------YVS------QVTVADIAGKRKW----
---------HFLCNCWLAVNLGDCERDRVFMPVS-------KRELFSFRH--LFSSMII-
--EKF-TQDCLWLSVATRHPWNEFTRVQRLTCYMTLLLCNMVI-------NV-MFWKVNS
TTTKR---DEQARVGPFAVTWSELLVSIQTAVIFFPISLVIGRLFPLIQPQEPLPV-FPP
IQASCPSDASSEPLSLTEVVEEL-----KETVGFLLRR----------------------
-NMYLLSECEPSSWHS---DSINELLKLLSGLVCSYLEHPG-CP-QQAGPYWAN--VVPE
NHHHFCSY---LLRVLQRLQSHLQTLGPTQADHPSDFLDAVHQLQK-LQ--ELLETHVL-
-------PTEQGLSREAT-SFPILSPEEGKQRLSKG--WHRWLT-----YFCWLLLGVTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SMI
LSLLQNTFISQPAKVIFLTLFY----------SL-----MLNRLPQLHK-----------
-EKEHQTRRIL-ALWARCPSS-LPGSRDKNNSIYVAPTMNTPVKRPERALKEKKFFKLTG
DVL-AQILFLTLLM-----TTVYSTQNSNRFYLRQAIHKSFSHRFSEIKLLKHFYTWA--
----------------------------------------NSTLLPNLYGDYRGKNTVQG
P-SCK------------CGIQL--VFHMPLHFAGCVNMTAPL-WAPK---------GLPP
G----THLSSFRFMSVHPRVIGPRGLVPTEE---FHRGINKVENLFTYSMR---SAFFTS
M----------RLDILTSLQIS--KNFAWSVM-SQV------------------------
----------------------SYYLLVCYY-------AFAQGRQLKQQRWRFFMRKRNL
LDMSIILLSFVILGLDLTVISLHKKHMVQYHYDRDRFINFYEAVKVNSAVIHLMGFLVLL
ATVQLWSLLYQNPRLQVIDRTLSKA---WDEVVGFLLVILILLTGYAI------------
----------AF--NLLFGWSISDYQTFLSSAVTVVSFLMGISHHEEVTAVNPVLGSFLI
-FTYVVLMVLMIINLFVSAILMAFGKERKSLKQTERGATLMDMLLLKLSSLLGIQQHQST
CEHT-----AL------------TATATDKLYFV-NFP-----------------

-----MMFQTGIWLWLCIGQNVLRG----AGLNL--QKEHRKSDCYQLNRIHCSFRGAQH
YCHRQ-GGQLMSTWNQDIRNHLKDYLEEGKKWWIEPDSHPLIKREKRCPAEVSANLFTRS
GLFPSNRCTYMIRNWDLVSSKVDLCSKEHFFICQGXXXXX-------XXXXXXXXXXXXX
XXXXXXXXXXXXXXX--------------------XX-----------------------
------------------------------------------------------------
--------------XXXXXXX---------------------------------------
-------------XXXXXXXXXXXXX----------------------------------
------------------------------------------------------------
---------------------XPTTL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------CQEMSTNILVLF-------V------------------
-----------------------------------------------------MAQ----
----------------TPEQMLLAISPPS-SPLPVKTKFGKPVA----ETSSEKPLSE--
-AL----------AVFR----EAMG-----------------------------------
------------------------------------------------------------
-----NVSRSIQDVQ-LVQKVQRACEILQHLKHFASQFSKTI-----------QINSLLY
PSEQLLKVQS-PSGNPFSRKAPIALCSFDSFSYDMESVGMSRVGAQQ--DS---------
------------------------------MQMEDTLETSLIALGNIQEALL-----LAS
QPSESSMIVTSS-----LATLMLRSQNISTLSSSSYTLGYPAPLRL--GLPSASAFHNLL
SKHQNVNI--------------------QVTGLAFNPFKHFDERDIVGSIGNVL------
---LTSNHKSL---RIQDLLEEAEIILWRDGSIE--------------------------
-----------------------TYPTSFNMSTDCFVITINITSLKESLIVWVEPENSLS
I--TLYLGFQYQPNVTHFH---LNITLPKEQ--IW-EKXXKYSWVLSPESL---------
-QHGAGTYYITAVVNESKKAPNRTSQRFSVTMAATQCY-------FWDHRNKTW---KSN
GCRVGPQSTVTKTQCLCSHLPSISSS FKTVARTVNIQ-DTVKLFHGVSRNPIGVSLLASL
FGFYIIFIVWAWRKDGEDMKKMKVTILADNCPNSQ SHYL------VQVFTGYRRKAATTA
KV-----------------------ILILYGSEGRSDPHHL-SDPHKVLFEQGAQDVLLL
TTRFPLG-ELHSIRLWHDNSGTSPSW--------YVN------QVIVSDLTTSKKW----
---------HFLCNCWLAVDLGDCRQDQVFTSVS-------KKELFSFRN--LYSSMIV-
--EKF-TQEHLWLSVVTCSPWNQVTRVQGLSCCMTLLICSMLI-------NI-MFWKLNG
E--------------SFAVTSSELLISIQTASILFPINLIIGRIFPLIQLQEKIPPHFIP
IQASSTLDTSFGPVTTQKIIEEL-----KEIVGFLHMK----------------------
-NACLPSQWAPG--SS---DSITDLIKGLSSLINSHLERQGSQW-QQTGSHLKN--EVPE
NLRNLNHY---LLRVLERLQFQCSTLKL---FQPHDFLHSAGQLQS-LR--ELMETQIL-
-------TMAQGPCSDIM-SFPMLDSEEEKSTILNY--LPKWSI-----YVCWLLLGVTS
LVS-----AFF--TALYSLKLNKDQ--AT-------SWVI-----------------SML
LSVLQNIFIIQPVKXXXXXXXX----------XX-----XXXXXXXXXX-----------
-XXXXXXXXXX-XXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-XQILFLVMLM-----ISTHSERILSRFYLNQAIHKKINNHFEEIKRIEDFYQWT--
----------------------------------------NNTFIPNLYGEYRGKGXXXX
XXXX---------------------------------XXXXX-XXXXX------------
-----------------------------------------XXXX--XX-----------
------------------XXX---------------------------------------
--------------------XXXXXXXXXXX-------XXXXGNR-MKQRWEYFTKKSNA
LDTSILLLTFTMLLLQLKCFFLHRRDMEQYRQNKSRFISFHESVQVSCALTYLLGVLVLL
TTIRLWSLLQLNTRLQVISTTLKRA---WDEAAGFLLIILILLTGYSI------------
----------TF--NLLFGWSISDYRTFFNSAITTVCLLKGIFDYHEVITLDPVLGSFLI
-TISVIFLVLVIINLFASAIILTFRKERKSIM----------------------------
-------------------------------------------------------

-----MMFQTGIWLWLCMGQTFLRG----GRSS---QKQTRKSDCYQLNRFHCSFRRAQR
YCHGQ-GAQLISSWSQDIQDHLKDYLEEGKKWWIEPNSHPLIKQKGK---DNPGKLFTRS
GLSPSTSCTYVIRNLDKVSSKVDLCSKEHFFICQGDVFRD-------HPHANYESHGRNT
HVNPR------TKKKKREISTMRSEIKEPD-----FP-----------------------
------------------------------------------------------------
--------------FHDSHVF---------------------------------------
-------------LNSCLLFLPLTDH----------------------------------
------------------------------------------------------------
---------------------HLSSR----------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------CHHFT-DIYQVS-------A------------------
-----------------------------------------------------SS-----
------------------------ICSGVDTSLPLTKINQLELN----GRAGN-------
EGH-------SETYSY------PVGRGHK-------------------------------
------------------------------------------------------------
--SKRF-----IYLA-LLPLSGTFWRQRGGWWQHTGPFGILAWLQLLSGSVANSSLPLLY
LSEQLLMGHS-WNRNSSSLKAPIALCLNY----KIEGFGNSEFQAPFP-MQ---------
------------------------------VRMEDMLETSLIALGKIQESFL-----QDS
QPSESSLIVTSS-----FATMMLRSQNISTLSLSSYTIQYPAPVHL--SFPSASALDNLL
NKHQSVNI--------------------HVTGLAFNPFKNFDKRDIVGSIANVL------
---LTANHKSL---QVQDLLEEAEIMLWRDSSIE--------------------------
-----------------------TYPTSFNMSTNCFVITVNITSLEESLVVSVEPENPLS
I--TLYLGFQYQPNITHFY---LNTTLPKDQ--LQ-EKDELYTWVLSPESL---------
-QHGTGTYYITAVVNKSETDPKAPFLGFSVTTATTQCY-------SWDPHNKTW---MSE
GCQAGPQSSLAKTQCFCNLLATI GSSWRSLPRTVNVQ-DTVKLFSRVTHNPIGVSLLAGL
LGFYILFAAWAWRKDREDRKKMKVTILADNYPNSQS HYL------IQVFTGYRRRAATTA
KV-----------------------VLILYGSEGRSDPHHL-SDPQKVVFERGAQDVFLL
TTRIPLG-ELHSIRLWHDNSGTSPSWQVFSFLFRYVN------QVIVSDLVTRKKW----
---------YFLCNCWLAVDLGECQKDQVFTSIS-------KKELFSFRN--LYSSMIV-
--EKF-TQDHLWLSMVTLSPWNQVTRVQRLSCCMTLLICNMVI-------NI-MFWKLRS
TKEDR---TGQDRVGPFAVTLSELFISIQTASILFPINLIIGRIFPLILPQEKLPLHLFP
PEASFTSDTSLGSVTTQKIIEEL-----KETVGFLHMK----------------------
-NACLPTEWEGSSWSS---DSVTELIKLLSSLIRCHLERRGGQW-QQTGSSLEN--EVPE
NLRNLNHY---LLKVLERLQFLCSTLVASPTRKAPDVLYSVSQLER-LR--ELVETQIL-
-------SMAQGSSSDIT-SFPMLDSEEEKPAFMNS--LSKWSI-----YICWLLLGVTS
LVS-----AFF--TALYSLDLNRDQ--AT-------SWVI-----------------SMV
LSILQNIFIIQPVKVMILTLFL----------SL-----LMTRLSWHNK-----------
-EKDQQMRKIL-ALLARCPSLSPPGLRDENNPIYRAPAINCSVKAPERTRKEKQLFRMTR
DIC-VQILFLVVLM-----ISTYSERNYNSFYFNQAIRKRINKHFEEIKLIKHFYRWT--
----------------------------------------NNTLIPNLYGDYRGVRGESS
SSKH---------------------------------NQLS-------------------
-----LMVYMMCYIP--RLLFSPL---------------FHLCKEREKRTL---SPLFLE
TKRDY-IYNPNPIPINPCDQAG--------------ESQTC--LLKLPMFSLGAFFSSIK
VNSLQITQ-TQKSFICFSALSIIYFLLLFYY-------TFVQGNRLKQQGWKYFTKKSNA
LDTCIIFISFIMMALQLKRVFLHKRYMQQYRHK-KRFTNLHEIVQVTAALTYLIGFLVLL
TTIRLWSLLRLNPRLHIISTTLKRA---WDEVVGFLLIILILLTGYSI------------
----------AF--NILFGWSISDYRTFSNSAVTIVGLLMGIFDSCEVITLDPVLGSFLI
-ITSVILLVLVIINLFVSAILLTFCKERKSIM---KEAPLTEILMQKLSNLLGIQRPQKA
ALPEQPVPVAAGTNMENFRE-----------------------------------

------LFRRRSWLWLYIIVGVIVGVSLGHELSN--SQPHGEKSCYRLYMLNCNFDEAND
YCKTQ-GEHLTLTWNQGLQTHIQRSYQKETTWWDCGLGLHPRIL--LVPLG-------DA
ADSEDRKCNSVTIYPNGILPKPDQCSETHHFICQIVG-PA-------ESGPGTILER---
------------KAQG--------------------------------------------
------------------------------------------------------------
-RSYW-------------------------------------------------------
--------------PLCFS-----LEIPKAMPWMIS--MAPNRSSQVTSATPASSSPPQV
TTATPAPSSSP---------------HVTPVTPV-------------SSSPPQVTPAT--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------PISNRSPW--------PESTIPAGRSLADTTSSPK
GDSHSEVLSTRPQTSFPSTAYWVSLGNRRQLGSFMILEGTCRPGDVAQWQNIGLRKPWEQ
ARKQHPSTASA-----SAPASTLLPCLSSDPPYLTQHLQSAQNVLQNRNKQLTSLQPDKI
FPSQQKLVPEIPAFQ-AHSELQKAYDILQRVRNSPLTSPTP--------A----------
-----------QNNSSRNFKTP--TSPLQPLGSTITTTEGSQQVLLPDTEQVRVLHAG--
-AFGIEAGGFETLSDL--------WLQSSF-KVEDMLEMSLMALGEIHKAFS-----QQS
LPLESAVTLTSP-----VATVVLSSHNVTSLPLSTYTLGGPAPLRL--GFPSAEALKELL
NKYTGVNL--------------------QVTGLAFNPFETSDDRNIVGSIGNVL------
---LSSDYQSL---HVHDLIEDIEIVLWRNASMK--------------------------
-----------------------IQPTNLNTSTDCFTITVNITSVEKTLIVTIEPESPLL
M--TLYLGFQDKQNHTHFY---HNTSLPRDQ--VW-QKDEEYTWVLTPEKL---------
-QYGTGTYYIMAVVNKSTEATQHTPILVSVVTAVTQCY-------FWDQNNRTW---RSD
GCQVGLQSTMLKTQCLCNHLTFF SSDFFILPRTVDVE-NTLKLLLHVTSNPVGVSLLASL
LGFYLLLGTWAWRKDRADLQKVKLTILADNDPGSAFH YL------IQVYTGYRRRAATTA
QV-----------------------VITLYGSEGHSEPHHL-CDPQKGVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGDNPSW--------YVS------QVIVSDMTVKKKW----
---------HFRCSCWLAVDLGHCERDRVFTPAS-------RRELSSFSH--LFSSTIV-
--EKF-TQDYLWLSVATRHPWSQFTRVQRLSCCMTLLLCDMVI-------NV-MFWKMGA
TTAKR---GSP-FVGPLAVTWSEIVISFQTAIILFPIHLVFGRLFQLIHPPETLPP-LPP
TQAACPSGLVCESPSPTQVVMEL-----KQTVGFLLRR----------------------
-NAHLLLEREQSSWSS---CDIDTLVTLLSSLICSHLEEQG-CH-QQTEARREA----AE
NHHHFCCY---LLQVLQRLKSHLNALGAAQAHHPCDFSGAVSQLQN-LQ--ELLQTQIL-
-------PREGGPCRHTT-SFPVLSPEEGKKRTSLC--LVRWLK-----YSCWLLLGVVS
LAS-----AFF--TTLYSLKLSKDQ--AT-------SWVI-----------------SML
LSVLQDIFVSQPMKVIILSFLF----------SL-----TANQMPWLNK-----------
-DKEQHDKRIV-ALWAKCSSS-APGLRDKNNPVYTAPAVTSSARHSGRAWKK-QLFKLTG
GSL-VQILFLGLLM-----ATVYSARDSSQFLLHQAISKRFSHRFSEIKLLKDFYPWA--
----------------------------------------NHTLLPNLYGDYSGFITDGN
SFLLGNVLLRQLRVPNSTLFPV--SLHEPETSQPQHQEDREN-YGVGW----APPDTNIT
-----ETDSIWHYQN--QELVGGYPIQ----------GEFATYSGGGYVVRLGRNASAAA
RVL-------RHLEQRRWLDHGTKVLFVELTVFNANVNLLCAVTLILESNSMGTFFTSLR
LDSLTSLQSSERSFAWI-ITQVSYYLLVCYY-------TFIQGCRLKRQRWKFLTRKRNL
LDTSIILISFSILGLNIQSLSLLHKNMLQYRRDRDRFISFHETLKVNSAVTHLMGFLVLL
ATVQLWDILRHNAQFQLISKTLNKA---WDEVVGFILLIVTLLSSYAM------------
----------TF--NLLFGWSISDYQSFFSSTVTVVGLLMGISSHKEVIALYPVLGSFLV
-LTSIILMGLVIINLFVSAILIVFGKERKAFE---KEPTLTDILLQKLSSLLGIGQQQNP
SSEKHADNTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKLL

-----MLSKGRTWLWLYLIAGIILG----RELSIISPELHGQKSCYQLNRFHCSFEEAQR
YCFAQ-GGHLAYPWNPEVQGLIWNSLKKGEKWWIGQNLPP-SKHHEGDHPAN----VAA-
--TTPASCTYMSRDSNQFSPKEDACSQGHYFICQSXXXXXXXXXXXXXXXXXX-------
XX----------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------XXX------X
XXX---------------------------------------------------------
--X--XXXX---------------X-------------XXXXXX----------------
---------------------------XXX------------------------------
------------------------------------------------------------
------------------------------------------------------------
---X-XXXXXXXXXXXXXSQILCHSISPFPSLPPKV------------------------
-----------------------------------------------------TGQL---
---------------------TAVTTVPASQPHPGVTPLARSESVTHTEKSTAEITSSPE
KDSRPDILTTHLQATFQNSSEE--------------------------------------
----------------------------------------------------------VI
EEISGNVSQANYDLQ-AYSKLQRACEILQGLTAFTPRSSKP--------AQVSAINSLIH
LKEQFLKIPF-QNSTSLGFKTAVIDCLFHSSNNGLQGKD-SPQGPKRDTEQV--------
---------------------------------EDTLEMSLVALGKIQEAFL-----QQN
QSSESSVTLTSS-----VAAVMLCSQNKSTLPLSSYTLGYPAPVRL--DLPSASALEELL
NKHPGVNV--------------------QVTGLAFNPFKDVDNRIIVGSIGSVV------
---LSSNSKSL---HVRDLMEDIEIMLWRNTSME--------------------------
-----------------------IHPTRLNMSTDLFMLTVDITSLEKSLIVSIEPESPLL
M--TLYLGFQYQPNLTHFH---LNITLPKDQ--VW-QKDEEYTWVLTPESL---------
-QHGVGTYYITALLNRSKEGGEQTPALVSVVTAVTQCY-------FWDDHNRMW---KST
GCQVGPHSTILRTQCLCNHLTFFGSD FFIVPRTVNVG-DTIKLFLRVTNNPVGVSLLASL
LGCYLILVVWAWRKDQADIPKVKVTVLADNDPSSQ LRYL------IQVYTGYRRRAATTA
QV-----------------------VITLYGSEGKSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-XXXXXXXXXXXXXXXXXX--------YVN------QVIVSDMAVQRKW----
---------HFLCNCWLSMDLGDGQRDQVFLPVS-------KKELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVITRHPWNQFTRIQRLTCCMTLLLYNMVI-------NV-MFWKMNS
PAART---GTP--VGPFAVTGSELLFSIQAAVILFPVNLVIGQLFPLIQSQETLCL-LPP
AQATCASDASFEPLSLAEVAEEL-----KETMGFLLRR----------------------
-NAYQLSECDQSLWNS---SDINKLVKLLYSLVYSHLEGQG-CH-QQEELCWAN--VAPE
NHRHFCRY---LLKVLQMLKSQVGSLALTQVHQLCDVRDVVSQLQK-LQ--ELVETHIV-
-------PIDRGPSREET-SFPILSPQEGKKVISNR--LPRWLP-----YICWLLLGVTS
LAS-----AFF--TXXXXXXXXXXX--XX-------XXXX-----------------XXX
XXXXXXXXXXXXXXXXXXXXXX----------XX-----XXXKMPWLSK-----------
-EKEQQTKRIL-MLLTKCS-S-TPGSRDKNNPIYVAPAINGPTKCPERTWEEKKFFKLTG
DIL-VQILFLILLM-----TAVYPANNTNRFYFHQAIQKSFSHRFSEIKLLKDFYPWA--
----------------------------------------NRTLLPNLYGDDRGKNLVLG
P-GCK------------CGVQL--VFQIPTKISEKLEKGLTF-----------CDTSWHP
R----PHISRFSFCSP----RGDQLMGLIPTGETQKRLTNENENS-TWSMK---STVFTS
V----------RLDSLTSLQTS-KKAFAWTVI-SQV------------------------
----------------------TYYLLVSYY-------TLKQVRRLKQQKWRFFTRKRNI
LDTSIIFISFVILGLDMKLISLHKKYMAQYHRDQDXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXX------------
----------XF--NLLFGWSLSDYQTLFSSAMTVVGLLMGISHYNEVITLDPVLGSFLI
-LTSVILMVLVIINLFVSAILMAFGKERKSLK---KEAALIDVLLQKLSSLLGIQRHTNT
SSEQ-----VA----T---------MGTDTEVLELT-------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MFGEGEQEVGQF---------KPPY
ESFEVPDPT--V-AQV----L-----------VEHNTSHVYTTPGEYSLTLLVST-AFEN
L TQQVPVSVRAA--LPAVAV AVGSQVLVAGQPVAFFPRPLPSPGGVLYTWDFGDGSPAVT
QPQPEVNHTFALRGMYHVRLEVNNTVSHV VAAISVRVFEELRGLT--VSV SSAVEQGVPV
--------------VVSAALDSGDNVTWTFDMGD--------------------GTVLMG
PEAT VEHVWARTGPGTVGASSPAGH-LARSLPMHVFV----------LEVLWIDPVAC IA
SQLHARLTAHVTGDPAHYV---FDWTFGDGSPNVSIQGDPTVTHS---------------
-FMNSGTFPLALVLSSRVNR----------------------------------------
-------------------AHYFSSVC-VEPVLGNVTLQPE RQFVRLGD---EVRLVAHA
WPPFPYRYTWDF--GTEDAAA------RVGGPEATFTYQLAGSYLVTVTAANNISAA NDS
ALVEVQEPVEVTGISVNS SHALEAAAAYLFSALGRGHPASFLWELGDGRQLQGPTVT---
HAYSSTGCFRVRVAGWNEVS RGEARLDVTV--QQRVRGLSVNASRTVVPLNGSVSFSTAL
EAG------SDVRYCWVLCDR--CTP----IPGG-------PTISYTFRSVGTFNIIVTA
ENEVGAAQDSIFVYVLQHI---EGLQVV GGGCCFPTNRTLQLQAVVRDGTNISYSWAAQR
D------------GGPSLAGSG----------KAFSLTVLEAGTYHVQ-LR--ATNMLGS
AS ANCTVDF-------------------VEPVGWLA VTASPNPAAVNTSVTLWAELAGGS
S------------------------------VSYSWS--------LEEGLRWET--QEPS
TTLSFPSPGLCLVTVVA--ENQLGSAN-----ASVE---VVVQ---------------VP
VSGLSIHA------RELDG GF-----------VVAGSTVPFWGQLAAGTDVSWRWAMPGG
SRQGQHVTVVLPDPGPVSVQLNASN--AV-------SW VMATHNLTVQEPIV-----SLV
L--WASRKVVEPGQPVHFQILLAAGSAVRFFLQVSGGGLEVLPVPHFSRSFPRVGDYTVS
VHAENRVSRAQ----AQVRVSVLEAVGGLQVPDCCGP AIAT-------------------
-----------------------------------GAERNFSARVQR--GSRVAYAWYFS
LQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFNELGGV NRTLLVEVQDAIQHVALRGP
----------------R CFANRSAHFEAAT-------SPSARRVSYRWDFGDGAPAEDT-
-------EVPWAAHS--YLQPGDYPVQVNASNL------------VSFFVA---------
------------------------------------------------------------
------------------QATVTVHVLACREPEVDV--ALPPQVLMRR-------SQRNY
LEAHVDLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXG------------------
---------------------ASRPG----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------YWKRQAIFLLRGIEWRKKLT-LSFCFP
RVP-------QHLGQSHWLEHCTKSLSVESVVFGANVNLFCVVTLILESNNAGAFFPSLR
LDTLTSLQASKKDFAWSLILQVIYYLLVCYS-------AFVQGHRLKQQRWRFFSRKRNI
LDVSIILISFVLLDLDRKRTSLHKKNMAQYRYERDRFISFYEAVQVNSAIVHLMGFLVLL
ATVQLWNLLHHNLRLQVIGRTRQSLGRGGGLLAGHLDPAHRLCHCCKPSFPKAAALESHC
FPRKHYTANHQFKLAMNFGK-KKEYENWFLVGSSTLHQQYGLKSD-------------IC
LLTSAH-------NVM--------------------------------------------
-------------------------------------------------------

-----MFFKGRTWLWLYITTGFVLG----SELHGSEQ--RGGNNCFQLSSFRCSFEGAEQ
HCHAL-GGHLAFTWNQEVQDLLWNFLEK-EKWWVGGNLTLPEKHQGKNHPAE----VTTR
PATKPTRCIYLTRSHNQTSSKEGSCLAKHYFICQAD-AFS-------DQDANYERNGNNS
HS----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------CGKPK------R
TKR---------------------------------------------------------
--EVIRPRS---------------K-----------VTSGDTRL----------------
-----------------------STMRHQP------------------------------
------------------------------------------------------------
---------A--------------------------------------------------
--EA-SMSK-TL----------CHRLSPFPSLPP--------------------------
----------------EV-----------------------------------TPQG---
---------------------VSVTPAPTSQPLPLTPGLPRPGSVTRAGKALVEITSSPK
EDSHPGVFTSHPQVSLQNASDQ--------------------------------------
----------------------------------------------------------II
DEITGNFSKAVLGFR-AHNKLQKACEILEGLAAFIPGFSES--------AQVRVINTLTD
LNEQLLQSPF-LNSSNPGSRTPVTICLLHSLNNVMKAGEASRPRHGHRVEQV--------
--------------------------------EN-MLKMSLLSLGRIQEAFL-----QQN
RCAEPEVTLTSS-----TAVLMLSRQNISTLPLSSYTLGDPAPVRL--GFPSASALEELL
KKHPGVDV--------------------QVTGLAFNPFRDFDEKKIVGSIGSVL------
---LSSNHKLL---QVHDLMEDIEIMLWRNTSVE--------------------------
-----------------------THRTSLNMSTDHFTITVNVTSLEKSLMVCIEPEGPLS
L--TLHLGFQHQP-------NLTHFHLPKEK--VS-QKDEEYTWVLTPEKL---------
-RYGVGTYYITAVLDKSKEGTQRTPTLLSVVTAVTQCY-------FWDSLNSMW---KSS
GCQVGPQSTLVRTQCLCNHLTYFGS DFFLVPRTVNVE-DVAELFLRVTSNPVGVSLLASL
VGIYMLIFVWAWRKDQADAQKVKVTILADNDPSSQ FHYL------IEVSTGHRRRASTTA
NV-----------------------VITLYGSEGRSEPHHL-CDSQKAVFERGGLDVFLL
GTPSSLG-ELHSLRLWHDNSGTSPAW--------YVS------QVTVTDIAGKRKW----
---------HFLCNCWLAMDLGDSERDRVFMPVS-------KKELFSFRH--LFSSMII-
--EKF-TQDCLWLSVATRHPWNQFTRVQRLTCYMTLLLCNMVT-------NV-MFWKVNS
TTTKR---DQQARVGPFAVTWSELLVSIQTAVIFFPISLVIGRLFPLIQPQEPLPV-FPP
IQASCPSDASSEPLSLTEVVEKL-----KETVGFLLRR----------------------
-NTYLLSECEPSSWRS---DSINELLKLLSSLICSYLEHPG-CP-QQAGHYWAN--VVAE
NHRHFCSY---LLRVLQRLQSHLQTPGPTQADHPSDFLDAVHQLQK-LQ--ELLETHVL-
-------PTEQGLSREAT-SFPILSPEEGKQRVSKG--WHRWLT-----YFCWLLLGVTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SMI
LSLLQNTFISQPAKVIFLTLFY----------SL-----MLNRLPQLHR-----------
-EKEHQTRRIL-ALWARCPSS-LPGSRDKNSSIYVAPTINSPVKRPERTLKEKKFFKLTG
DVL-AQILFLTLLM-----TTVYSTQNSNRFYLRQAIHKSFSQRFSEIKLLKHFYTWA--
----------------------------------------NSTLLPNLYGDYRGKTTVQG
P-SCK------------CGIQL--VFHMPLQEPLEHWR-KFR-WLCQYDCTSVGTQSSTP
R----DPSKQFQVYVC-----SPKACVLLNVYMVHQKLNHLSENKCSFLFS---GAFFTS
M----------RLDVLTSLQIS--RNFAWSVT-SQV------------------------
----------------------IYYLLVCYY-------AFAQGRQLKQQRWRFFMRKRNL
LDMSIILLSFVILGLDLTLISLHKKHMVQYHYDRDRFINFYEAVKVNSAVIHLMGFLVLL
ATVQLWSLLYQNPRVRVIGRTLSRA---WDEVVGFLLVILILLTGYAI------------
----------VF--NLLFGWSISDYRTFLSSAVTVVSLLMGISHHKEVTAVNPVLGSFLI
-FTYVVLMVLVIINLFVSAILMAFGKERKSLKQTEREATLMDMLLLKLSSLLGIRQHQSA
CKQT-----AL------------TATAMDKLYFV-NFP-----------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPAP--HGQNNCYQLNRFQCSFEEAEH
YCHVQ-RGFLAHIWNKEVQDLIRDYLEEGKKWWIGQNIMPLKKHQDNKYPAD----VAAN
GPPKPPSCTYLSRNFIRISSKGDKCLLKYYFICQTGD-FL-------DGDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRHK------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGHL----------------
-----------------------PTTCHYP------------------------------
------------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CHPISPFPSVLP--------------------------
----------------SI-----------------------------------TSQV---
---------------------TSAASEPSSQPLPVITQLTTPVSVTHAGQSLAETTSSPK
EEAHPNTFTSYLQVSLQKASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFSKP--------AQVNLINSLIY
LSEELLRIPF-QNNNSLGFNVPATVCPFHSFNNVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLVEFGNIGEAFL-----EQN
QSPESSVTLTSS-----IATLLLSRQNISTLPLSSYTLGHPAPVRL--GFPSALALKELL
NKHPGVNV--------------------QITGLAFNPFKDLDNRNIVGSIGSVL------
---LSANRKLL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSLNMSTHQLTITVNMTSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYYITAVLSERQEGAQQTPGSVSVITAVTQCY-------YWEIHNQTW---SST
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTIELFLRVTNNPVGVSLLASL
LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTWTSLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--MGPFAVAWSELLISIHTAVILLPINLVIGRVFPLVEPQETLPF-FPP
VQASCLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---WDITKLVKLLSSLVSSHLEGQG-CH-QQGERHWAL--VVPE
NHRHFCCY---LHRVLQRLKSHLGTLGLTQGHQSFDFLDAASQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPISNG--LSKWLT-----SVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPVKVVFFTFLY----------SL-----MMSRMPRLNK-----------
-ENEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKHPERTLKKKKLFKLTG
DIL-VQILFLTLLI-----TAIYSAKNSNRFYLHQAIWKTFSHQFSEIKRLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNVVLE
PSHCK------------CGVQL--IFQIPHTKTYEKVEEGQL-AFCDNGHTCGRPKSLFP
G----LHLRRFSYIS------SPRPMVLIPTDELHKRLTSKNENGFSYIMR---GAFFTS
V----------RLESFTSLQMS-KKGCVWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCQLKQQKWRFFTGKRNI
LDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLHHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEAALIDTLLQKLSNLLGISWPQKT
SSEQ-----AT----T-------TAMGNDTEVLDE-LP-----------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HRQNNCYQFNRIHCSFEEAEH
YCQGQ-RGFLADIWKQEVQDLIRDFLEEGKKWWIGQNVMPLKKHQDEKYPAD----VAAH
GAPKPPSCTYLSRNVNRISSKEGKCFLRHYFICQTDG-IL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRPE------K
TKR---------------------------------------------------------
--GVEIARD---------------K-----------TPPGPGPL----------------
-----------------------STSCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEPSSQPLPVITQLTTPVSVTHAGQSMAETTSSPK
EAAHLNTVTSHLQVSLHNASGQ--------------------------------------
----------------------------------------------------------VV
DETAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFVKP--------AQVNLINSLIY
LSEELLRIPF-LNNSSLDFKVHATVCPFHSCNDVIKAEEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQN
RSSESSVTLTSS-----IASLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSVGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNISME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VVTLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSPLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
VQASCLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDITKLVKLLSSLISSHLEGQS-CH-QQTERHLAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGLTQGHQPCDFLDAASQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKFISNG--LSKWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPGKVVFFTFLY----------SL-----MISRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKDSNRFYLHQAIWKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPGLYGDYRGKSAVLK
PSHCK------------YGVQL--IFQIPCTTIYEKVKEGQL-VFSDMAVPVGIPRAC--
---------SVTSVH------PGPRGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------SLESFTSLQMS-KKGFAWSVI-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCRLKWQKWRFFTGRRNI
LDTSIILISFIILGLDMKSISLLRKNMARYRDDQDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSQA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTGVLDE-LP-----------------

-----MFFKGRTWLWLYITTGFVLG----SELHGPEQ--RGGNNCFQLNSFRCSFEGAER
YCHAQ-GGHLAFTWNQEVQDLLWDFLEK-EKWWVGGNLTLPKKHQEKNHPAD----VTAR
PATKPARCVYLTRSHNQTSSKEGSCSAKHYFICQAD-AFS-------DQDANYERNGNNS
HS----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------RGKLK------R
TKK---------------------------------------------------------
--EVIRPRS---------------K-----------VTSGNVTS----------------
-----------------------V------------------------------------
------------------------------------------------------------
---------A--------------------------------------------------
--AL-MDSK-TL----------CHHLSLFPSVPP--------------------------
----------------EV-----------------------------------TPQG---
---------------------VSVTAAPTSKPLPLTPELPGPGSVTRAGKALEEITSSPK
EDSHPSVFTSHPQVPLQNAPDQ--------------------------------------
----------------------------------------------------------VI
DEITGNFSKAVLGLR-THNKLQKACEILEGLAAFIPGFSES--------AQVRVINTLTD
LNEQLLQSPF-LNSSNPGSRTPVTVCLFHSLNNVMKAGESSRPRHGHSV-----------
--------------------------------EN-MLKMSLLSLGRIQETFL-----QQN
RCAEPEVTLTSS-----TAALMLSRQNISTLPLSSYTLGDPAPVRL--GFPSASALEELL
KKHPGVDV--------------------QVTGLAFNPFRDFDKKKIVGSIGSVL------
---LSSNHKLL---QVHDLMEDIEIMLWRNASME--------------------------
-----------------------THPTSLNMSTDHFTITVNVTSLEKSLIVCIEPEGPLS
L--TLYLGFQHQP-------NHTHFHLPKEK--VS-QKDEKYTWVLRPEKL---------
-WYGVGTYYITAVLDKSKEGTRQTPTLLSVVTAVTQCY-------FWDSLNSMW---KSS
GCQVGPQSTLVRTQCLCNHLTY FGSDFFLVPRTVNVE-DVAELFLRVTSNPVGVSLLASL
VGIYMLIFVWAWRKDQADAQKVKVTILADNDPSSQFH YL------IEVSTGYRRRAATTA
SV-----------------------VITLYGSEGRSQPHHL-CDSQKVVFERGGLDVFLL
GTPSSLG-ELHSLRLWHDNSGASPAW--------YVS------QVTVTDIAGKRKW----
---------HFLCNCWLAVNLGDCERDRVFMPVS-------KRELFSFRH--LFSSMII-
--EKF-TQDCLWLSVATRHPWNQFTRVQRLTCYMTLLLCNMVI-------NV-MFWKVNS
TTTKR---DEQARVGPFAVTWSELLVSIQTAVIFFPISLVIGRLFPLIQPQEPLPV-FPP
IQASCLSDASSEPLSLTEVVEEL-----KETVGFLLRR----------------------
-NMYLLSECEPSSWRS---DSINELLKLLSGLICSYLEHPG-CP-QQAGPYWAN--VVPE
NHHHFCSY---LLRVLQRLQSHLQTLSPTQADHPSDFLDAVHQLQK-LQ--ELLETHVL-
-------PTEQGLSREAT-SFPILSPEEGKQRLSKG--WHRWLT-----YFCWLLLGVTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SMI
LSLLQNTFVSQPAKVIFLTLFY----------SL-----MLNRLPQLHK-----------
-EKEHQTRRIL-ALWARCPSS-LPGSRDKNNSIYVAPTMNTPVKCPGRALEEKKFFKLTG
DVL-AQILFLTLLM-----TTVYSTQNSNRFYLRQAIHKSFSHRFSEIKLLKHFYTWA--
----------------------------------------NSTLLPNLYGDYRGKNTVQG
P-SPA------------NVGYS--WFSIC---PYKTQE-NWK-WMVQEHLGLSERELE--
---------------------------------GQKANLKALNSRCSFFLS---GAFFTS
V----------RLDILTFLQIS--KNFAWSVM-SQV------------------------
----------------------IYYLLVCYY-------AFAQGRQLKQQRWRFFMRKRNL
LDMSIILLSFVILGLDLTVISLLKKHMVQYHYDRDRFINFYEAVKVNSAVIHLMGFLVLL
ATVQLWSLLYQNPRLQVIDRTLSKA---WDEVVGFLLVILILLTGYAI------------
----------AF--NLLFGWSISDYQTFLSSAVTVVSLLMGISHHKEVTAVNPVLGSFLI
-FTYVVLMVLMIINLFVSAILMAFGKERKSLK---RGATLMDMLLLKLSSLLGIQQHQST
CQQT-----AL------------TATATDK-------------------------

-----------SWLWVCIRVGVLLG----RERSN--PEQHGKNNCYQFNRLSCNFQEAET
YCSNQ-KGRLAHTWNPELQAIIQRFPNKETMWWVGGSLPPLRNHQEASYSG-------VV
PDLGTPKCTSVVTGSNDIISTRDQCSNKHHFICQADA-FP-------QRGASNGKNEHGS
S-NGKNE---PKKKRGAQSENRILPPMMPHLPLPLHSRT---------------------
------------------------------------------------------------
------------------------------------------------------------
---------------LCFPISSYSSVLPKATPPMIV--TSPTRSSNVTSGTPASTSSSQV
TSATPASTSSS---------------QVTSATPA-------------STSPPQVTSATPA
SSSSPQVTSAT-------------PASTXXXXXXXXXXXXXXXXXXXXXXXXXX------
XX-------XXXXXXXX-------XXXXXXXXXXXXXXXX-------------XXXXXXX
XXXXXXXXXXXXXXXXVTSATPALSSSSQVTSATPASTSPPQVT-------------SAT
PALSS-SSQVTSATPASSSSSQVTSVTPA-------------------------------
-----------STSPPQVTSATPAPASSPQVTSATPASSSSPQVTSATPALNSSSQVTSA
TPAST-----------SSSQVTSATPVPNNPPWTVMTEVTRSESTIPAGRSLADITSSPK
EDSHPEVISAHPQMSFQSTANQVSLETEDK------------------------------
------------------------------------------------------------
----------TPAFQ-AHSDFQKACDILQRVRNFPPTSPTP--------AQVSVANLLMN
LSEQLLMIPF-QKNDSWNFKTPAATCPLQYFGSTATTNDASQKILQQEP-----------
------------------------------EQVEDMLEMSLMALGEIHKAFC-----QQS
LSPELAVTLTSP-----VATLVLSSQNVSSLPLSTHILGDPAPLRL--GFPSAEALKDLL
SKHPGVNL--------------------QVTGLAFNPFETSDDRNIVGSIGNVL------
---LSSGYQSL---QVHDLIEDIEIMLWRNASME--------------------------
-----------------------TQSTSLNTSTDHFTITVNITSMEKTLIVTIEPESPLL
M--TLYLGFQDKPDHTLFY---LNTSLPREQ--VW-QKDEEYTWVLTPESL---------
-RHGIGTYYIMVVVNKSTEATQYTPIPVSVVTAVTQCY-------FWDQNNRTW---RSD
GCQVGLQSTILKTQCLCNHLTFF SSDFFIVPRTVDVE-NTIQLLLHVTKNPVGVSLLASL
LGFYILLATWAWRKDRADMQKVKVTVLADNDPSSAFH YL------IQVYTGYRRRAATTA
QV-----------------------VITLYGSEGHSEPHHL-CDPQKTVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGDNPSW--------YVS------QVIVSDMTVKKKW----
---------HFQCNCWLAVDLGNCERDGVFTPAS-------KRELSSFRH--VFSATIL-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCDMVI-------NV-MFWKMGG
TTAKR---GEP--IGPFAVTWSEIVISVQTAIILFPIHLVFGRLFQLIHPPETLPP-LPP
TQAACPSGLACESPSPTQVVTEL-----KETVGFLLRR----------------------
-NTHLLSEREQSWWSS---CDINKLVKLFSSLISSHLEDQG-SH-QQTESRQND--VVSE
NHHHFCRY---LLHVLRRLKSHFSSLSAALVQQPCDFSETVSQLQN-LQ--ELLETQTL-
-------PKE-RPCRHST-SFPVLSPEEGKKPVLFI--LFKWLK-----YSCWLLLGVIS
LAS-----AFF--ITLYSLELNKDQ--AT-------SWVI-----------------SMM
LSVLQDIFINQPIKVIFLTFLF----------SL-----TANQMPWLNK-----------
-DKEQHSKRIV-ALWAKCSSS-APGLRDENNPIYTAPVMTSSAKHPKGAWKK-QLFKLTG
GTL-VQILFLSLLM-----AMVYSARDSSQFLLHQAIRKRFSHRFSEIKLLEDFYPWA--
----------------------------------------NHTLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRIPKGMLFPA--SLYDQMNAHPQHQEDIEN-YGVGW----SPPDTNIT
-----ETDSIWHYQS--QESLGSYPTQ----------GEFATYSGGGYVARLGRNSSAAA
RVL-------QHLEQRRWLDHGTKVLFVELTVFNANVNLLCAVTLILESNNVGTFFTSLQ
LDSLTSFQSAERSSARI-TSQVSYYLLVCYY-------TFIQGCRLKRQRWGFLTRKRNL
LDTSIILISFSILGLNMQRLSLLHKSMLLYRHDRDRFISFCEALKVNSAVTHLMGFLVLL
ATVQLWELLRHNAQLRVISKTLNKA---WGEVAGFILIIMILLSSYAM------------
----------TF--NLLFGWSISDYRSFFSSTVTVVGLLMGISNHKEVIALYPILGSILV
-LTSIILMGLVIINLFVSAILIVFGKERKALK---KEATLTDVLLQKLSNLLGIRQYQNP
SSEKQADSTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKLL

-----MLLQRPSWLWLYLRISVVLGVLLGREPSI--PEQHGKNSCYQLNRLYCSFHEAEM
YCHAQ-RGHLANTWNPKLQDFLQNSPQKETVWWVGINLKLPRKQPGITQTGR----ALVL
SVGKPDECTSVVKRSNAFFPRWDQCLKKHHFICQAVA-VP-------PQGANIWRNELD-
----PWK---PMKKRGAELERHMIPGDGPPLSM---------------------------
CHPPAP------------------------------------------------------
------------------------------------------------------------
---------PELSEILCFPIDPVSSVLPKATHKMTI--TSPTRSSQVTSVVTASSSPPQV
TSDTPASSSSPPQVTSDTPASSSSPPQVTSDTPS------------SSSSPPQVTSDTPA
SSSLPQVTSDTPASSSPPQVTSDTPASSSPPQVT-------------SDTPASSSPPQVT
SDTPASSSPPQVTSDTSASSSPPQVTSDTPASSSPPQVTSDTPASSITPQVTTDTPVSSS
PPQVTSDTPASSSPPQVTSDTPASSSPLQVTSDTTASSSPPQVT-------------SDT
PASSSSPLQVTSDTPASSITPQVTSDTPVSSSPPQVTSDTPASSSSPPQVTSDTPASSSS
PPQVTSDTPSSSSSPPQVTSDTPASSSLPQVTSDTPASSSPPQVTSDTPASSSPPQVTSD
TPASSS----------SPLQVTSDTPVPNSPPWPVITEVTRLESTIPTGRSLADITLNAK
EDSPPGVISTHPQMSFQSSTNQ--------------------------------------
----------------------------------------------------------VI
EETAGKLILANPASQ-AHSEFQKACSILQRLRDFLPTSSTS--------A----------
-----------QRNNSWSSHTPAVSCPFQPLGSLLTTKKNSHQMAQQDTEQRP--IDEAY
TAFGINSEGPTFTSDV--------RLQSEF-EVEDMLETSLMALGEIHRTFC-----QQS
LCPQSAVTLASP-----TATLVLSSQNVSSLPLSTYTLGEPAPLRL--GFPSAEALKELL
DKHPGVNL--------------------QVTGLAFNPFETSDDSNIVGSIGNVL------
---LSSEYQLI---RVHDLIEDIEIVLWRNASME--------------------------
-----------------------TQPTSLNTSTDCFTISVNITSLEKTLIVTIEPESPLL
M--TLHLGFQDKPGHTHFY---LNISLPRGQ--VW-QKDEEYTWVLTPESL---------
-WYGTGTYYIMAVENKSAETAQHTPVLVSVVTAVTQCY-------FWDRYNRTW---KSD
GCQVGPKSTILKTQCLCDHLTFF SSDFFIVPRTVDVE-NTIKLLLHVSNNPVGVSLLASL
LGFYILLATWAWRKDQADTQKVKVTVLADNDPSSAFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGHSEPHHL-CDPQKTVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGNSPSW--------YVS------QVVVSDMTVKKKC----
---------HFQCNCWLAMDLGNCERDRVFTPAS-------RSELSSFRH--LFSSTIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCDMVI-------NV-MFWKMGG
STAKR---G-E-RLGPLAVTLSELLVSIQTSVILFPIHLVFGRLFQLVHPPEVLPP-LPL
SQAACPSVLVRETPSLTQVVKEL-----KETVGFLLRR----------------------
-NTHLLSECEQSSWSS---CDINTLVKLLSGLVYSHLEDQG-CH-QQTESRWED--GVSE
SHSHFCRY---LLRVLQSLKLRLGALAAVQEHQPYDFSEAVSQLQN-LQ--ELLRTQTL-
-------PKEPRPCRHST-SFPILNTEGGKKPVPFC--LFRWLR-----YSCWLLLGVIS
LTS-----AFF--ITLYSLELSRDQ--AT-------SWVI-----------------SMM
LSVLQDIFICQPIKIYFMTLLF----------SL-----MANHMPWLTK-----------
-DKEHHARRIV-ALWAKCPSS-APGLRDKNNPIYTAPAMNHLDRRTKKVWRK-RLFLLTA
GSL-VQILFLTLLM-----TTVYSAKDSSRFFLHRAVWKRFSHGFSEIKAVEDFYPWA--
----------------------------------------NRTLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRIPNDTHSPV--SLHEHMNSYPQHQEDREN-YGAGW----VPPDTNIT
-----KADSIWHYQS--PESLGGYPIQ----------GEVTTYSGGGYVVRLGRNHSAAT
RVL-------QHLEQRHWLDHYTKALFVEFTVFNANVNLLCMVTLILESSGVGTFFTSLR
LDSLTSLQSSERGFAWI-ISQVAYYLLVCYY-------AFVQGCRLKRQGLAFFTRRRNI
LDTSIILTSFSILGLNMQSLSLLHTNMQQYRRDPDGFISFSEALRVNSVATHLMGFLLLF
ATVRVWDLLRHHARLQVINKTLTKA---WDEVLGFIMIIMILLSSYAM------------
----------TF--NLLFGWSISDYQSFFSSVVTVVGLLVGIPKHKEVVALSPVLGSFLV
-LSNIILMGLVIINLFVSAILIVFGKERKACE---KEATLTDMLLQKLSSLLGIRQHQKP
ASEKHADSTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKVL

-----MFFKGRTWLWLYSTTGIVLG----NELDSP--EQHGEHNCYQLNRFHCSFQEAED
YCRAQ-RGHPACTWNQEVQDLLRDFLEEGKK-WVGENLTLLGKHQEKNNPAD----VTAH
WAPMP-TCIYLF-NPSRISSKVDLCSLG-HFICQADA-FS-------DQDASYERNGNNS
HSHRKPK---RTK-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--R---------------------------------------------------------
--EVTIPRNKM--------------------------TSVA-------------------
--------------------AHLSTTCHQPAR----------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------ATLXXXXCHSISPFPSIPPGVTQQ---------------------
------------------------------------------------------------
--------------------GVSVMPVPTSQPLPVPPELTRPASVTHAGKAPVEITSSRK
EDSHPGVFTTHPQASFHNTSDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
----------------------------------------------------------XX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXX--------X----------
------XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
--------X----------------------XXXXXXXXXXXXXXXXXXXXX-----XXX
XXXXXXXXXXXX-----XXXXXX---XX------XXXXXXXXXXXX--XX--XXXXXXXX
XXXXXXXX--------------------XXXXXXXXXXXXXXXXXXXXXXXXX-------
------XXXXX---XXXXXXXXXXXXXXXXXXXX--------------------------
--------------------------------XXXXXXXXXXX-XXXXXXXXX--XXXXX
X--XXXXXXXXXXXXXXXX---XXXXXXXXXXXXX-XXXEQYTRVLTPESL---------
-QYGVGTYYVTALLNRSKEGAQQMPALFPMVTAVTQCY-------FWD----TW---RSS
GCQLGPQSPLLRTQCLCNHLTYLGGD FFIVPRAVKAE-DTAELFPRVTSNTIGVPLLASL
IGVYMLIFVWAWRKDQADMQKVRVTVLADNDPSSQ FHYL------IEVSTGYRRRAATTA
NV-----------------------VITLHGSEGQSEPHHL-CDSQKAVFERGGLDVFLL
GTPSSLQ-ELHSLQLWHDSSGVSPSW--------Y---------VIVTDMAGKRKW----
---------HFLCNCWLAMDLGE-ERDWSFIPVS-------EKELFSFRH--LFSSMIV-
--ENL-TQDCLWLSVT-THPWTQFTRVQRLTCCMTLLLCNMVT-------YV-TF-KMNG
TTTKR---H---EHGPFAVTWSELLVSIPTAVILFPISLGIGRLFLLIQPQEPLPL-FPP
IQASCLSDASFEPLSLTEIDEXX-----XXXXXXLLRR----------------------
-NTYL-LECEQSSWSSFFSYNINQLVKLLSSLVCCYLEGQG-RH-QRAEPYWAN--VVPE
NHHHFHSY---LLRVLRKLQSHLGTLGPAQAHQPCDFLDAVSQLQE-LQ--ELLEMHIL-
-------PTEQGPSRDAARAFPILSP-DGKQPISNG--QLRWLT-----YFCWL-LGVTS
LAS-----AFF--AALYNLELNKDQ--AT-------SWII-----------------SI-
LSLLQNIFI-QPVKVIFLTLFH----------SL-----LLNRMLL-HK-----------
-EKEH--QRIL-AVLARCPSS-LPGSRDENNPICVAPAMNGPXXXXXXXXXXXXXXXXXX
X-XXXQILFLILLM-----TAVYSAHNSNRFYLRQAIHKSFPYRFSEIKLLKHFYPWA--
----------------------------------------SSTVLPNLYRDYRGKNTVLG
PS-CK------------CGVQL--VFQTPAVTHKLE--KGPL-FQN--DCT-CGPKGPLP
G----PHLSRFRYVC------SPRPMRLIPTDEFHKRLINKIETLFTNNMKXXXXXXXXX
XXX-------XXXXXXXXXXXXXXXXXXXXXX-XXX----------------X-------
----------XXXXXXX-----XXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX-XXXXXXXXXX-X
X---XXXXXXXXXX--XXXXX-XXX---XXXXXX----XXXXXXXXXX------------
----------XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVIALNPVLGSFLI
LLTSVVLMVFVIINLFVSAILMTFGKERKSFK---KEAALMDMLLLKLSSLLGIQQHQNT
LSKQTAV----------------TAMATDNEVSKD--------------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPAP--HGQNNCYQLNRFQCSFEEAEH
YCHVQ-RGFLAHIWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPAD----VAAN
GPPKPLSCTYLSRNFIRISSKGDECLLKYYFICQTGD-FL-------DGDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YQRHK------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGHL----------------
-----------------------PTTCHYP------------------------------
------------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CPPISPFPSVPP--------------------------
----------------SV-----------------------------------TSQV---
---------------------TSAASEPSSQPLPVITQLSTPVSVTHAGQSLAETTSSPK
EEAHPNTFTSYLQVSLQKASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFSKP--------AQVNLINSLIY
LSEELLRIPF-QNNNSLGFKVPPTVCPFHSFNNVTKAGEGSWLESKRHTEPV--------
--------------------------------ED-ILEMSLVEFGNIGEAFL-----EQN
QSPESSVTLTSA-----IATLLLSRQNISTLPLSSYTLGHPAPVRL--GFPSALALKELL
NKHPGVNV--------------------QITGLAFNPFKDLDNRNIVGSIGSVL------
---LSANRKLL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSLNMSTHQLTITVNITSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYYITAVLSEREEGAQQTPSLVSVITAVTQCY-------YWEIHNQTW---SSA
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTIKLFLRVTNNPVGVSLLASL
LGFYVITVLWARKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTWTSLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSIATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--MRPFAVAWSELLVSIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
VQASYLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---WDITKLVKLLSSLVSSHLEGQG-CR-QQGERHWAR--VVPE
NHHHFCCY---LHRVLQRLKSHLGTLGLTQGHQSCDFLDAASQLQK-LQ--ELLESHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPISNG--LSKWLT-----SVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNIFISQPVKVVFFTFLY----------SL-----MMSRMPRLNK-----------
-ENEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLE
PSHCK------------CGVQL--IFQIPCTKTYEKVDEGQL-AFCDNGHTCGRPKSLFP
G----LHLRRFSYIR------SPRPMVLIPTDELHKRLTSKNENGFSYIMR---GAFFTS
V----------RLESFTSLQMS-KKGCVWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCQLKQQKWRFFTGKRNI
LDTSIILISFILLGLDMKSISLHKKNMARYHDDQDRFISFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVIGRTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEAALIDTLLQKLSNLLGISWPQKT
SSEQ-----AA----T-------TAMGSDTEVLDE-LP-----------------

-----MLLQRRSWLWLYIRIGVILGDILGRKPSI--REQHGGNSCYQLNRLFCDFQEADN
YCHAQ-RGRLAHTWNPKLRGFLKSFLNEETVWWVRGNLTLPGSHPGINQTGG----DDVL
RNQKPGECPSVVTHSNAVFSRWNLCIEKHHFICQAAA-FP-------PQGASIWRNEFGP
---GPLL---PMKRRGAETERHMIPGNGPPLAM---------------------------
CHQPAP------------------------------------------------------
------------------------------------------------------------
---------PELFETLCFPIDPASSAPPKATHRMTI--TSLTGRPQVTSDTLASSSPPQG
TSDTPASSS-PPQVTSATSAS-SSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPA
SSSPPQVTSATSASSSPPQGTSDTPASSSPPQVTSATSASSSPPQGTSDTPASSSPPQGT
LDTPSSSSPPQGTSDTPASSSPPQGTSETPASNSPPQGTSETPGFSSPPQVTTATLVSSS
PPQVTSETPASSSPTQVTSETPASSSPTQVTSDTPASNSPPQGT-------------SDT
PGFS-SPTQVTTATLVSSSPPQVTSDTPASSSPPQVTSDTPASS-SPPQVTSETPAS-SS
PPQVTSDTSA-SISPPQVISDTPASSSPPQVTSETPASSSPTNMTSDTPASSSPTNMTSD
TPASS-----------SPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQ
EDSPLGVISTHPQMSFQSSTSQ--------------------------------------
----------------------------------------------------------AL
DETAGERVPTIPDFQ-AHSEFQKACAILQRLRDFLPTSPTS--------A----------
-----------QKNNSWSSQTPAVSCPFQPLGRLTTTEKSSHQMAQQDMEQHP--MDGAH
NAFGISAGGSEIQSDI--------QLRSEF-EVEDMLETSLMALGEIHRAFC-----QQS
LCPQSAVTLASP-----SATLMLSSQNVSTLPLSTYTLGEPAPLTL--GFPSAEALKELL
NKHPGVNL--------------------QVTGLAFNPFKTLDDKNIVGSIGNVQ------
---LSSAYQSI---RVHDLIEDIEIMLWRNASME--------------------------
-----------------------TQPTSLNTSTDHFTISVNITSLEKTLIVTIEPESPLL
M--TLHLGFQDQLAHTHFY---LNISLPRDQ--VW-QKDEEYTWVLTPENL---------
-WYGTGTYYIMAVENKSTEAAQHTPVLVSVVTAVTQCY-------FWDRYNRTW---KSD
GCQVGPKSTILKTQCLCDHLTFF SSDFFIVPRTVDVE-NTIKLLLHVTNNPVGVSLLSSL
LGFYILLAMWASRKDREDMQKVKVTVLADNDPSSASH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGHSEPHHL-CDPEKTVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGDSPSW--------YVS------QVIVSDMTTRKKW----
---------HFQCNCWLAVDLGNCERDRVFTPAS-------RSELSSFRH--LFSSTIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVI-------NI-MFWKMGG
TTAKR---GTE-QLGPLAVTLSELLVSIQTSIILFPIHLIFGRLFQLIHPPEALPQ-LPF
IQAAWPPALVCESPSLTQVVKEL-----KETVGFLLRR----------------------
-NTQLLSECEPSSCSS---CDINKLAKLLSGLIYCHLEDEG-CH-QQTESHWED--AVSE
NHYHFCRY---LLQLLRRLKAHLEALGATQDHQSCDFSEAVSQLQN-LQ--ELLETQTL-
-------RRGPGPCRHST-SFPILSPGEGKKPMSFC--LFRWLK-----CSCWLLLGVIS
LAS-----AFF--ITLYSLELDKDQ--AT-------SWVI-----------------SMM
LSVLQDIFISQPIKVIFLTLLF----------SL-----MANHMPWLNK-----------
-DKEQHARRIV-ALWAKCPWS-APGLRDKNNPIYTAPAMNNLAKPTRKAWKK-QLSKLTG
GTL-VQILFLTLLM-----TTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWA--
----------------------------------------NGTLLPNLYGDYRGFITDGN
SFLLGNVLIRQTRIPNDIFFPG--SLHKQMKSPPQHQEDREN-YGAGW----VPPDTNIT
-----KVDSIWHYQN--QESLGGYPIQ----------GELATYSGGGYVVRLGRNHSAAT
RVL-------QHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILESSGVGTFLTSLQ
LDSLTSLQSSERGFAWI-VSQVVYYLLVCYY-------AFIQGCRLKRQRLAFFTRKRNL
LDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLF
ATVRVWDLLRHHAQLQVINKTLSKA---WDEVLGFILIIVVLLSSYAM------------
----------TF--NLLFGWSISDYQSFFRSIVTVVGLLMGTSKHKEVIALYPILGSLLV
-LSSIILMGLVIINLFVSAILIAFGKERKACE---KEATLTDMLLQKLSSLLGIRLHQNP
S-EEHADNTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKVL

-----MFFKGRSWLWLYVRTSIILG----SELNSPER--RGQNNCYQLNSFHCSFEEAEH
YCHAQ-GGFLAHIRNQEVPDHIWDFLEEGKKWWIGQNVMPLKKHQDEKYPAD----IVAH
GDTKPPSCTYLSRNFSRISFKGDKCSLGHYFICQTVDAFL-------DGDARYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PWRPE------K
TKR---------------------------------------------------------
--EAEIPRN---------------K-----------MPPGGAHL----------------
-----------------------STTCHHP------------------------------
------------------------------------------------------------
---------P--------------------------------------------------
--HA-HLSK-ML----------CHPISPFSSVLP--------------------------
----------------KI-----------------------------------TAQV---
---------------------TPVTSEPSSQPLPARTEPTSPVSVTRAGQSQMETASSPE
EDTHPNSFTSHRPASLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIVGNFSRAVHGLQ-AHNKLQEACEVLQKLTALTPRFSKP--------AQVHLINSLIY
LSEQFLRIPF-QNNSSLGFKVPATICLFHYFNNVIKAGEGSWQGSKRDPEQV--------
--------------------------------ED-MLEMSLVALGNIGEAFL-----EQK
QPPESSVTLTSS-----IASLLLSRQNLSTLPLSSYTLGHPAPVRL--GFPSASALKELL
NKHPGVNV--------------------QVSVKLIVI------GMKMGSYG---------
-------------------HVGIGIMLWRNVSLE--------------------------
-----------------------THPTSVNMSTDQFTITVNVTSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYIWVLTPEHL---------
-QHGIGTYYITAVLRESQEGVQQMPSLVSVITAVTQCY-------YWDSHNQTW---SSH
GCQVGPQSTILRTQCLCNHLTFF ASDFLVVPRTVNVE-DTIILFLHVTSNPVGVSLLASL
LGFYMIIVVWAWRKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGQSEPHHL-CDPQKTVFERGGLDVFLL
TTHSSLG-ELHSLRLWHDNSGLSPSW--------YVT------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELLSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNLFTRVQRLSCCMTLLLCNMVI-------SI-MFWKISG
TTGKR---DEQ--MGTFAVAWSELLISIHTAVILFPINLVIGRLFPLIQPQETVPL-FPP
IQVSCLLDASVEPLSVTMVVEEL-----RETVRFLLRR----------------------
-HTYLLSECKQPSWSS---CNITKLVELLSSLLSSHLEGQG-CH-QQAERHRAR--VVPE
NHHHFCCY---LCRVLQRLKSHLGTLGLTQGHQTCDLLAAASHLQK-LQ--ELLETHML-
-------PTEQEPFREVT-SFAILSSEEGKRPISNG--LSKWLS-----SFCWLLLGLTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWMI-----------------SVI
LSVLQNVLISQPVKVVIFTFFH----------SL-----MMSRVPRLHK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPTMNSPTKHPERTLKKKKLFQLTG
DIL-VQIFFLTLLM-----TTIYSAKNSNRFYLHQAIRRTFAHRFSEIKLLQDFYPWA--
----------------------------------------NHILLPNLYGDYRGKNAVLE
LSHCK------------CGIQL--IFQIPATKTHEKVRKVSW-LLL--------------
----------------------------IRPYLWN-------ENGFSDIMRRNWSAFFTS
V----------RLESFTSLQMS-KKGFVWSVI-SQV------------------------
----------------------IYYLLICYY-------AFIQGCRLKRQKWRFFTRKRNI
LDTSIILISFIILGLDMKSISLHKKNMEQYHHDRDRFISFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLWVISRTLSRA---WDEVSGFLLIILILLTGYAI------------
----------AV--SPHIAVSPSIWAV--------------CLLSSQVIALDPVLGTFLV
-LTSVILLVLVIINLFVSAILMAFGKERKSLK---RQVALIDMLLLKLSNLLGIRQPQKT
SSEQ-----AA----T-------TSMGIDTEVLEDELP-----------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HGQNNCYQFNRFHCSFEEAEH
YCHGQ-RGFLAHIWNQEVQDLIQDFLEEGKKWWIGQNVMPLRKHQDENYPAD----VAAP
GAPKPPSCTYLSRNLSRILSKEDNCFLRHYFICQTDG-VL-------DRDAHYERNENNS
RL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------CQRTE------K
IKR---------------------------------------------------------
--GVAIARD---------------K-----------MPPGPGPL----------------
-----------------------STTCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NT-----------------------------------TSQI---
---------------------T-ATSEASSQPLPVITQLTTPVSVTRAGQSLAETTSSPK
KAAHLNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLTALTPRFFKP--------AQVNLINSLIY
LSEELLRIPF-LNNSGLDFKVPATVCPFHSFNDVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQD
QSPESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QITGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNVTSLEKSLIVSIDPDSLLL
M--TLYLGFQYQPNYTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QYGIGTYCIRAVLSESQKGAQQTPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFFAS DFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQ FHYL------IQVYTGYRRRAATTA
KV-----------------------VVTLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DKQ--LGPFGVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
VQASCLSDASVEPVSAAIVVEEL-----KETVRFLLRR----------------------
-DTYLLSKCEQPPWSS---CDVTKLVKLLSSLISSHLEGQS-CH-QQAERHWAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGLTQGHQPCDFLDAARQLQK-LQ--ELLEIHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPISNG--LSKWLT-----AVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNVFISQPGKVVFFTFLY----------SL-----MMSRMPQLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPIYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIQKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGEYRGKNAVLK
PIHCK------------YGVQL--IFQIPCTTIYEKVEEGQL-VFSDGRTC-GHPKSLFP
G----LHLRRFSYIC------SPRPMR-FPTDELHKRLTSKNDSGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFAWSII-SQV------------------------
----------------------IYYLLVCYH-------AFIQGCRLKRQKWRFFTERRNI
LDTSIILISFIILGLDMKSISLLRKDMARYRDDRDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHQEEVINLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KEVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------VI
DEIAGNFSKAVHGSP-AHSALQKACEVMRTLKAFMPGSSES--------AQVSVIDSLVY
LKGHLLKSPF-QNSSSLGFHVPVTVCLFHSPNDVVQAGEAGQQRSKPDVEQV--------
--------------------------------EN-VLKTSLLALGRMQEEFL-----QQN
NFSESSVTLTSS-----IATLMLSSQNISTLPLSSYTLGYPAPVRL--GFPSASALEELL
NEHPEVNV--------------------QVTGLAFNPFKDFDDKNIVGSVGSVL------
---LSSNHKLL---QVRDLVEDIEITLWRNVSTE--------------------------
-----------------------THPSSLNTSTEHFLITVNVTSLEKSLIVCIEPEHPLS
M--TLYLGFQYQPNHTHFH---LSITLPKDQ--VW-QKDEEYTWVLTPESL---------
-QYGIGSYYITGVLKESKESAQQPPTLFSVVTAVTQCY-------FWDSRNSTW---KSD
GCQVGPQSTILRTQCLCNHLTYFGS DFFIVPRTVNVE-DTIKLFLRVTNNPVGVSLLASL
LGFYMLIFVWAWRKDQADMQKVKVTVLADNDPSYQ FHYL------IEVSTGYRRRATTTA
KV-----------------------VITLYGSEGQSEPHHL-CDSQKAVFERGGLDVFLL
SARSSLG-DLHSLRLWHDNSGVSPSW--------YVN------QVIVSDVAGKRKW----
---------HFLCNCWLAMDLGDCECDRVFIPVS-------KKELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLTCCMTLLLCNMVI-------NV-MFWKING
TTAKR---DEQ--VGPFAVTWSELLISLQTAVILFPINLVIGQLFPLIQPQEPLPP-FPP
IQASCLSDASLEPLSLAKVVEEL-----KETVGFLLRR----------------------
-NTYLLSECEPSLWCS---YNINKLVKLLSSLIYSHLEAQG-CH-QQAGSYWAN--AVPE
NDRHFRYY---LLRVLQRLQCHLSTLGPTQLDQPCDLLDVASQLQK-LQ--ELLETHLL-
-------PAEQGSSRETT-SFPILSPAEGKKSISTG--LPRWLT-----SICWLFLGVTS
LAA-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SMI
LSVLQNIFISQPVKVVFLTLLS----------SL-----MLNRMPWLHK-----------
-EKEQQTKRIL-ALWAKCSSS-LPGSRDKNNPIYVAPAMNSPVKRLERPLKDKQLLKLTG
DIV-VQILFLILLT-----TVAYSAQNPSRFYLHQAIQKSFSHGFSEIKLPEHFYPWA--
----------------------------------------NRTLLPNLYGDYSGENTVPG
P-SCK------------CGVQL--VFQDPSTTHSTLEML--A-GFSIWLHLGGHPKGPLR
G----PHLSRFRFVC------SPKGSVMPPAFELTSRVTDRHEDMCSLLFS---GAFFTS
V----------RLDTLRSLQTS-KKDFAWSVV-SQV------------------------
----------------------IYYLLVCYY-------AFMQGRRLKQHRWRCFTRKRNI
LDMSIILISFVVLGLDVKLIALHKKNMAQYRYDRDRFISFNKAVKLNSTVIHLMGFLVLL
ATVQLWNLLHHNPRLQVIGRTLSKA---WDEVVGFLLVILILLTGYAI------------
----------AF--NLLFGWSISDYRTFFSSAVTTVGLLMGISHHKEVIALDPVLGFFLI
-LTSVILMVLVIINLFVSAILMAFGKERKSLK---VEATLIDTLLQKLSSLLG---PAKT
EHEQ-----TA----M-------TTMGIDTEVLKDELS-----------------

-----MFFKGRSWLWLYIRTSIILG----SGLNR--QEQHGKNNCYQLNMFQCTFKEAEN
YCLTH-RRYLAYTWNRKVQYLIKNYLEEGTKWWIGQKSILIKHQ--QSNPAS----VAAH
RAGKDTNCTYISRISDLVSSEEDNCLQRHYFICQSDA-FXXXXXXXXXXXXXXXXXXXXX
XXXX----------X---------------------------XX----------------
------------------------------------------------------------
-XXXXXXXXXTAPP----------------------------------------------
------------------------------------------------------------
-----I------------------------------------------------------
------------------------PSCHPVAHINVXXXXXXX------------------
------------------------------------------------------------
------XXXX-------------------------------------------------X
-XXX-XXXX-XX----------X----XX---XX--------------------------
----------------XX-----------------------------------XXXX---
---------------------XXXXXXXXXXX---X-----XXXXXXXXX------XXXX
XXXX-X-----XXX----XXXX--------------------------------------
--------------------------------------------XXXXXXXXXXXXXXVL
NELVRNFSKAIYDLQ-THSE-QQACEVLQKLTAFIPRISKP--------AKTSVVDSLVY
LSEQFQKIQF-HNSSSLHFRVPVTVCLLDSLKNIMNTAEAGWQRSDGDVEWA--------
---------------------------------DNMLERSLQALRKIQEAFL-----QQS
SFLEYSVTLTSS-----VATLMLSSQNVSTLPLRCYTLGDPAPVRL--DFPSASALEELL
NENPGVNV--------------------QVTGLAFNPFKNFDNKNIVGSIGNVL------
---LSSNNKLL---QVRDLMEDIEXXXXXXXXXX--------------------------
----------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX--
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXEEYTWVLTPESL---------
-KYGTGTYYITAVLNKSMEDAQWMPTLLSVITATTQCY-------FWDSHNRMW---RSN
GCRVGPQSTVSRTQCLCNHMTYFTSD FFVVPRTVNVE-DTIRLFLQVTSNPVGVSLLASI
LGFYMVIVVWAWRKDQADIQKVKVTVLADNDPSSQ FYYL------IQVYTGYRRRAGTTA
KV-----------------------IITLYGSEGSSEPHHL-CDSQKAVFERGGLDVFLL
TTQSSLG-ELHSLRLWHDNSGISPSX--------XXX------XXXXXXXXXXXXX----
---------XXXXXXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXH--LFSSMIV-
--EKF-TQDHLWLSVATRHPWNQFTRVQRLTCCMTLLLCNMVI-------NV-MFWQINR
TTASR---DEQ--VGPFAVT--KLLISIQTAVMLFPIXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXEL-----KETVGFLLRR----------------------
-NTYLLSECEQSSWSS---NDINKLVTLLSSLVCSHLEAQG-SH-QQAESVSAN--VVPE
NHRHFCHY---LLQVLRRLQSHLGSLAITKADQPCDCFDAGSQLQN-LQ--EILEKHIL-
-------PVDQGPTREVT-SFPLLISEEGKKPLSNG--LSRGLA-----YLCWLLLGVTS
LAS-----AYF--TALYTLELNKDE--AT-------SWVI-----------------SLV
LSVLQNTFISQPIKVVVLTFIF----------SL-----ILNRVPWLNK-----------
-EKEQQ--RIL-AVLAKCPSS-LPGTRDKNNPIYRAPAMNNPMRPPERTLKDKKLFRLAG
DIL-VQILFLILLM-----TTVYSANNSDRFYLNQAIRKRFSHCFSEVKLLKDFYPWA--
----------------------------------------IHTLLPNLYGDYRGRNTVLG
SSHCK------------CGVLVPKI------PAVIHQKPGK--LAFSDDYVYGHPKAFLP
G----PPLSRFSSVC------SPKIMGPIPTG------ENKNEN-LSYI-----------
--------------------------------------------------MESALFTSVK
LDSLTSHETSKNSFVWSVISQVIYYLLVCYY-------TFIQGRQLKQQRWSYFSRKRNI
LDMSIILISFIILGLDMKCLSLHKKNLAQYHHDRDXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXX------------
----------XF--NLLFGWSISDYRTFLSSTVTTVGLLMGISHHKEVIALDPILGSFLI
-LTIVILMVLVIINLFVAATLMAFGKEMKSLK-------------KELSSLLGIQQHRNT
PLSKQTIMTAV----STG-----------TEVSV-----------DGLS------

-----MFLRGSLWLWLSLRASVILG----QQQWSPEP--RGQNNCYQLNRFHCSFEEAEN
YCHSL-GGELAYTWNQEVQELIWDSLEKGKKWWTGQNIMLQEKHRERNKTAD----VATG
--PPPKSCMYVSRTSSGLWSHKDLCSQRHYFICQTDDLFS-------NQDASYKRNGNGS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YWRPE------K
TKR---------------------------------------------------------
--KVTIPGD---------------K-----------GNTGP--------HL---------
-----------------------STVCQRS------------------------------
------------------------------------------------------------
-------APA--------------------------------------------------
--HA-NHSK-TL----------CHSSGPPAPVPP--------------------------
----------------TV-----------------------------------LQPG---
---------------------VPETAAPRRGPDLRTPEPPGEAPEDP---------APVP
QAPRPGPLTALPEASFQNVSDQ--------------------------------------
----------------------------------------------------------VL
AELAGNLSQTIRGLQ-THSHLKKACEDLQRLTAFLPRFSES--------TQVSVINSFIH
LNKQLLLSPS-ENGSS------LTVCLFHSLHEAKEAGQERWQNPGQSSEQV--------
--------------------------------ADNRPDMPWPAHGKTPEAFL-----PQN
QFSGSSMALTSS-----IATLMLSSRNISTLPLSSYTLGYPAPVRL--GFPSATALEELL
NKHPGVDV--------------------QVTGLAFNPFKDFDDTNIVGSIGNVL------
---LSSNRKLL---QLHDLVEDIEITLWRNASIE--------------------------
-----------------------THPTSLNMSTDHFVISVNITTLEKSLIVCIEAENPLL
M--TLYLGFQYQPNHTHFH---QKITLPKGQ---A-PKDEEYTWVLTPRRL---------
-QYGMGTYYVTAVLNRSDEGAQQSPTTFSVVTALTQCY-------FWDSHNNTW---TSD
GCQVGLQSTVLKTQCLCDHLTYFGSD FFIVPRTVDVA-DTVKLFLRVTNNPVGVSLLASL
LGLYMLLFIWAWRKDQDDRRKVKITVLADNEPGWQ FHYL------VQVHTGYRRRAATTA
KV-----------------------VITLYGSEGRSNPHHL-WDSQKAVFERGGLDVFLL
CTQSSLG-DLHSLRLWHDNSGASPSW--------YVS------QVIVIDMMAKKKW----
---------HFLCNCWLAVDLGDGTRDRVFLPVS-------EKELFSFRH--LFSSTIV-
--EKF-TQDCLWLSVATRHPWSPASRVQRLACGAALLLCNMLT-------NT-MFWRTSG
AAAQR---GQQ--VGPFMVTWSELCVSIQSAVILFPINLVIGWLFQMLQPQAPPPL-SPP
-QSSSPAEASLEPLSLPRVAEEL-----KETVGFLLRR----------------------
-NAHLLSECEQSSWSS---HNINKLVKLFSDLVCSHLEGPG-CH-QRAEPPQEN--AAPE
NHLHFRRY---LLRVLQRLQGPLRMLGDAQAT--QDFLAVAGQLQR-VQ--ELLETHIP-
-------PADPGPGRAST-SFPILSSEEGKSFLSKG--LPGWVT-----YISWLLLSVTS
LVA-----AFF--TALYSLELNKDQ--AT-------SWVI-----------------SMI
LSFLQNIFISQPVKVVFVTLWF----------SL-----TMNRMPRFDK-----------
-EKEQQ--RIL-ALLASCPPS-LPGSRNRNDPIYVAPAVDSPVKRPERTWKGKKLLKQTG
EIL-VQILFLALLL-----TTVYSAQNPNRFHLHQTLRKSFSRRFSQIKLLKHFYPWA--
----------------------------------------HHTLLPSLYGEYRGENLGS-
---C---------------------FRRPSHGAGNLERGLP--------PGSCPPYGPHP
G----PQLSLFAYVC-----------------------------------P---RTFSAS
M----------RLESLTPLPAS-KEDLAWFII-PQS------------------------
----------------------IYYLLICYY-------TFIQGRQLKQQRWRFFTRKSNI
VDLSVILLSFVTLGLDIRRISLYQKSLARYRSDPDRFISFYEALKVNSAVLYLVGFLVLL
ATIQLWSLLHRNPALQVIGRSLSRA---WDEVVGFLLVILILLTGYAI------------
----------AF--NLLFGWSISDYRTFFSSIVAVVGLLMGITQHEKVIALDPVLGSFLI
-FTSVLLMVLVIINLFVSAILMAFGKERKLLK---KAATLTDILLQKLSSLLGIQKQQKT
KIAR-----PA----A-------DTKGVSKGE-----------------------

-----MFF-RGTWLWLYIRIGIILG----RELNTPDQ--RGKNNCYQLNRFHCSYEEAED
YCRMQ-GGHLAYTWNPEVQHLLWDFLEEGHKWWIGQNLKLLGKHQENNNLAG----VMPP
WAPGPISCIYVSRNSNWISSNVDFCSLGHSFICQAGK-FL-------DHPDQHERHGNNP
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------HWRPE------E
TRG---------------------------------------------------------
--EMAVPRN---------------K-----------KTPEHGAI-----HP---------
-----------------------APPCHHP------------------------------
------------------------------------------------------------
---------A--------------------------------------------------
--HA-DLSK-TL----------CHSISPFPSALP--------------------------
----------------RV-----------------------------------TWQV---
---------------------LSVTWVPTSHPLSVTPALPRPAPKEQSGQALVEVTSSPK
ENTHTEVVTTHLQTSFQDASDQ--------------------------------------
----------------------------------------------------------VV
YETARNLNKAIHGLQ-TNSKLQTACEMLQKLTALIPEFSKS--------AQVSVISPLVD
LNEQLPDSVS-QSNGIRGFENPVTVCLIHSLDDVVEAGKASLQRSKHDIKQV--------
--------------------------------EN-TLEMALLALGKIQEVFL-----QQN
RFSESLVTLTSS-----VATLVLSSQNMSTWPLSSYTLGSPALVRL--GFLSASALEEVL
NRHPGVNV--------------------QVTGLAFNPFKDFDDKNIVGNIGSVL------
---LSSNQKLF---QVHDLMGDIEIMLWRNVSME--------------------------
-----------------------THPTSLNVTSDHFIIIMNITSLEKSLIVCVEPESPLL
M--TLYLGFQYQPNHTRFD---LNITLPKDQKCIF-QKDEEYTWVLTPESL---------
-QYRIGTYHITATLNKSKESAQQTPTLFSVVTAVTQCY-------FWDSHNSTW---KST
GCHVGPRSTVLRTQCLCNRLAYFGS DFFIAPRTVNVE-DTIKLFLRVTTNPVGVSLLISL
LGFYMLTCVWAWRKDQADMQKVKVTVLADNDPSSQFH YL------LQVSTGYRRKAATTA
KV-----------------------VITLYGSERRSEPHHL-CDSQKAVFERGGLDVFLL
STKSSLG-ELHSMRLWHDNSGTSPSW--------YVN------QVIVSDMASKRKW----
---------CFLCNCWLAVDLGECQRDRVFMPVS-------KKELFSFRH--LFSSIIV-
--EKL-TQDYLWLSVLTRHPWNRFTRVQRLTCYMTLLLCNMVI-------NV-MFWRTSS
TTAKR---DEQ--VGPFAVTWSQVIISVQTAVLLFPVNLVIGRLFPLIQPQEPRPL-FPP
SQASCLSDATFEPLSLTEVAEEL-----KETVGFLLRR----------------------
-NTYLLSECEQSLWTS---YSINKLVQLLSSLIYSHLERHG-SH-QQAGPHRAN--VVPD
SHHHLCCY---LLGVVQRLHSHLSAVGPTQVDQPCDVLDATNQLQK-LQ--KLLETRVL-
-------HLEQGPSREVT-SFPLLSPEEGKEPIAYS--LPRGVT-----YICWLCLGVTS
LVA-----AFF--TALYSLELTKDQ--AT-------SWVM-----------------SVI
LSVLQNIVISQPIKAIFLALFD----------SL-----MLSRMPWLTK-----------
-EKEQQTRRIL-ALVAKCS-P-LPGSRDKNNPIYVAPAANSPVKRPERTMKEKKLFKLTG
DIL-VQVLFLILLM-----TTVYSAQNSNRFYLHQALRKSFSRHFSEIRLLKHFYLWA--
----------------------------------------NHTLLPSLYGDYRDREALQE
QQPCL------------CSCPS--SFHLPHRIVFKHKSDRSGFVCLCDKNLCHCIFGNIP
G----AHDFTFSQFL------TKLPLCLVPRIYIHKFLSSRGINA-LY---LLLGTFFTS
L----------RLDTLTSFQA--KKDFAWSVI-SQV------------------------
----------------------VYYLLVCYC-------AFIQGHRLKQQRWRFFTRKRNI
LDMSIILISFVLLGLEVKLTSLCKKNMAQYHYDRDRFISFREAIKVNSAAIHLMGFLVLL
ATVRLWNLMHHIPRLQVIGTTLSKA---WDEVVGFLLVILILLTGYAI------------
----------AF--NLLFGWSISDYRTFFSSAVTVVGLLMGISHHEEVIALDPILGSFLI
-ITSVFLMVLVIINLFVSVILMAFGKERKSLKTL-KEGTLIDMVLQKLSSLLGIQQHQNT
-------------------------------------------------------

-----MFFKGGSWLWLYIRTSIILG----SELNSPSP--HGQNNCYQLNRFQCSFEEAER
YCHVQ-RGFLAHIGNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPAD----VAAH
GPPKPPSCTYLSRNFIRISSKEDKCLLKYYFICQTGD-FL-------DGDAHYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YPRHK------K
TKK---------------------------------------------------------
--GVAIARD---------------K-----------MPPEPGHP----------------
-----------------------PTTCHYP------------------------------
------------------------------------------------------------
---------L--------------------------------------------------
--PA-HLSK-TL----------CHPISPFPSVLP--------------------------
----------------SI-----------------------------------TSQV---
---------------------TSATSEPSSQPLPVITQLTTPMSVTHAGQSLAETTSSPK
EEAHPNTFTSYLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSRAVHGLQ-AHNKLQEACEFLQKLIALTPRFSKP--------AQVNLINSLVY
LSEELLRIPF-QNNDSLGFKVPATVCPFHSFNNVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLVEFGNIGEAFL-----EQN
QSPESSVTLTSS-----IATLLLSRQNISTLPMSSYTLGHPAPVRL--GFPSVSALKELL
NKHPGVNV--------------------QITGLAFNPFKDLDNRNIVGSIGSVL------
---LSADRKLL---QVHDLMEDIEIMLWRNVSVE--------------------------
-----------------------TYPTSLNMSTRQLTITVNLTSLEKSLIVSIDPDSPLL
M--TLYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEQL---------
-QHGIGTYYITAVLNERQEGAQQTPSLVSVITAVTQCY-------YWEIHNQTW---SNT
GCQVGPQSTILRTQCLCNHLTFFAS DFFVVPRTVNVE-DTIELFLRVTNNPVGVSLLASL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQ FHYL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKAVFERGGLDVFLL
TTWSSLG-DLHSLRLWHDNSGVSPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKRNS
TTAKR---DEQ--MGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
IQASCLSDASVEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---RDITKLVKLLSNLISSHLEGQG-CH-QQGERHWAR--VVPE
NHHHFCCY---LRRVLQRLKPHLGMLGLTQGHQSCDFLDAASQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPMSNG--LSKWLT-----SVCWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWMI-----------------SII
LSVLQNVFISQPVK----------------------------------------------
----------------KCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLE
PSHCK------------CGVQL--IFQIPHTKTYEKVEEGQL-AFS-DGHTCGHPKSLFP
G----LHLRRFSYIC------SPRPMALIPTDGLHKSLTSKNENGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFVWSII-SQV------------------------
----------------------IYYLLVCYY-------AFIQGCRLKQQKWRFFTGKRNI
LDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFINFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLHHSPRLRVISSTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLI
-LTSVILMVLVVINLFVSAILTAFGKERKSLK---KEAALIDMLLQKLSNFLGISRPQKT
SSEQ-----AA----A-------TAMSSDTEALDE-LP-----------------

-----MLLQRRSWLWLYIRIGVFLGDILGHKPSI--PEQHGGNSCYQLNRLFCDFQEADN
YCHAQ-RGRLAHTWNPKLRGFLKSFLNEEIVWWVRGNLTLPGSHPGINQTGG----DDVL
RNQKPGECPSVVTHSNAVFSRWNLCKEKHHFICQTVA-FP-------PQGASIWRNEFGP
---GPLL---PMKRRGAETERHMIPGNGPPLAM---------------------------
CHQPAP------------------------------------------------------
------------------------------------------------------------
---------SELFETLCFPIDPASSAPPKATHRMTI--TSLTGRPQMTSDTLASSSPPQG
TS----------------------------------------------------------
------------------------------------------------------------
----------------------------------------DTPGFSSPPQVTTATLVFSS
PPQVTSDTPASSSPTNMTSDTPASSSPTNMTSDTPASSSPPQMI-------------SDT
PGFN-SPPQVTTATLASSSPQ---------------------------------------
--QVTSATSA-SISPPQVISDTPASSSPPQVTSETPASS---------------------
----------------SPTNMTSDTPASSSPPWPVITEVTRPESTIPAGRSLANITSKAQ
EDSPLGVISTHPQMSFQSSTSQ--------------------------------------
----------------------------------------------------------AV
DETAGEQVPTIPDFQ-AHSEFQKACAILQRLRDFLPTSPTS--------A----------
-----------QKNNSWSSQTPAVSCPFQPLGRLTTTEESSRQMAQQDTEQHP--MDGAH
NAFGISAGRSEIQSDI--------QLRSEF-EVEDMLETSLMALGEIHRAFC-----QQS
LCPQSAVTLASP-----SATLMLSSQNVSTLPLSTYTLGEPAPLTL--AFPSAEALKELL
NKHPGVNL--------------------QVTGLAFNPFKTLDDKNIVGSIGNVQ------
---LSSAYQSI---RVHDLIEDIEIVLWRNASME--------------------------
-----------------------TQPTSLNTSTDHFTISVNITSLEKTLIVTIEPESPLL
M--TLHLGFQDQPAHTHFY---LNISLPRDQ--VW-QRDEEYTWVLTPENL---------
-WYGTGTYYIMAVENKSTEAAQRTPILVSVVTAVTQCY-------FWDRYNRTW---KSD
GCQVGPKSTILKTQCLCDHLTFF SSDFFIVPRTVDVE-NTIKLLLHVTNNPVGVSLLSSL
LGFYILLAMWASRKDRADMQKVKVTVLADNDPSSASH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGHSEPHHL-CDPEKTVFERGALDVFLL
STGSWLG-DLHGLRLWHDNSGDSPSW--------YVS------QVIVSDMTSRKKW----
---------HFQCNCWLAVDLGNCERDRVFTPAS-------RSELSSFRH--LFSSTIV-
--EQF-TQDYLWLSVATRHPWNQFTRVQRLSCCMALLLCDMVI-------NI-MFWKMGG
TTATR---GTE-QLGPLAVTLSELLVSIQTSSILFPIHLIFGRLFQLIHPPEALPQ-LPF
IQAAWPPTLLWESPSLTQVVQEL-----KETVGFLLRR----------------------
-NTQLLSECEPSSWSS---CDINKLAKLLSCLIYCHLEDEG-CH-QQTESHWED--AVSE
NHYHFCRY---LLQLLRRLKAHLEALGATQDHQSCDFSEAVSQLQN-LQ--ELLETQTL-
-------RRGPGPCRHST-SFPILSPEEGKKPMSFC--LFRWLK-----CSCWLLLGVIS
LAS-----AFF--ITLYSLELDKDQ--AT-------SWVI-----------------SMM
LSVLQDIFISQPIKVIFLTLLL----------SL-----MANHKPWLNK-----------
-DKEQHARRIV-ALWAKCPSS-APGLRDKNNPIYTAPAMNNLAKPTRKAWKK-QLSKLTG
GTL-VQIIFLTLLM-----TTVYSAKDSSRFFLHRAIWKRFSHRFSEIKTVEDFYPWA--
----------------------------------------NGTLLPNLYGDYRGFITDGN
SFLLGNVLIRQTRIPNDIFFPG--SLHKQMKSPPQQQEDREN-YGAGW----APPDTNIT
-----KADSIWHYQS--QESLGGYPIQ----------GELATYSGGGYVVRLGRNHSAAT
RVL-------QHLEQRRWLDHCTKALFVEFTVFNANVNLLCAVTLILESSGVGTFLTSLQ
LDSLTSLQSSERGFAWI-VSQVVYYLLVCYY-------AFIQGCRLKRQRLAFFTRKRNL
LDTSIVLISFSILGLSMQSLSLLHKKMQQYHCDRDRFISFYEALRVNSAVTHLRGFLLLF
ATVRVWDLLRHHAQLQVINKTLSKA---WDEVLGFILIIVVLLSSYAM------------
----------TF--NLLFGWSISDYQSFFRSIVTVVGLLMGTSKYKEVIALYPILGSLLV
-LSSIILMGLVIINLFVSAILIAFGKERKACE---KEATLTDMLLQKLSSLLGIRLHQNP
S-EEHADNTGS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGSTKVL

-----MFSLGRGWLWLCIRTAVLLG----NPLNAPGQ--QGKRHCYQLHRLQYSLPEAEK
HCHDR-GGHLLNPWNQTVQGFIQKSLEEGTTWWIGQKRRLERKHSAPQRRKP----PDVI
SQLPHFSCTLVSRNAGQTTTQEDSCSNKHFFICQTGKDFLI------SQDAIYKRNENNS
NPQT--------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RPMPQ----R
NEK-ASG-----------------------------------------------------
--NLSLLRS---------------HSP---FI------P---------------------
----------------------LPLVCSYS------------------------------
------------------------------------------------------------
------------------------------------------------------------
-WSS-SFSK-----------NLCQPVSSCPLTE---------------------------
----------------------------------------------------VTPLV---
---------------------TKATSAPPSPSLPGISELTLPAAATHAAGSVVRSPPRPA
QDAQPGALTTLPQASPWTTADQ--------------------------------------
----------------------------------------------------------TT
DETAGNLRGVTDDVQ-AHRELQRACKVLQELSGFTSRLSTP--------AQVNAINSLIS
LSEQLLQMPF-QN-SSLAFRMPVTSCLTDPLSNVLSTTEESWQRPTGGPEQV--------
---------------------------------EDVLEMALVALGRIHEAGV-----QQN
PASGSSVTLSSA-----LAVTMLSSRNASTLPLSSYTLGHPAPVSL--GFPSAAALEELL
SKHPGVNV--------------------QVAGLAFNPFKDFDNRDIVGSIGTVL------
---LSSNLESL---QVHDLMEDIEIVLWRSESLD--------------------------
----------------------PAQPSSLSLSTEQLVITLNITSSEESLILSVQPDIRLP
V--TLYLAFQHQPEPADCH---LNITLPKDQ--VW-QKDEEYTWVLTPESL---------
-RYGIGTYYVTAVLNGDA----ERPALVSVVTAVTQCY-------FWDSHNRTW---RSD
GCQVGPRSTVSRTQCLCNHLTFFGS DFFILPRTVNVK-DTIRLLLRVTSNPVGVSLLASL
LGCYVVLAAWAWRKDRADTQKVKVSVLADNDPSCQ FHYL------VQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKAVFERGALDVFLL
TTKHPLG-ELHSLRLWHDNSGVSPSW--------YVN------QVVVSDMTVKKKW----
---------HFLCNCWLAVDLGDCQRDRIFLPAS-------QRELLSFRH--LFSCMIV-
--ENF-TQDYLWLSVATRHPWNRFTRVQRLSCCATLLLCNMLI-------NV-MFWKAGG
SAGRR------APVGLLAVTWSELHVSIQTAVILFPINLVIARLFPAAQPPETQPP-FPP
TQASSLSDAPVAPLSRAKVLEEL-----QETVGFLLRR----------------------
-RSCLLSECEQPSGSS---CDLGQLVKLLCSLVCAHIEEGG-CR-QQPGPPRVR--VAPE
SQRHLCCY---LLGVARRLESDLGALSLSPVPHPWDFADAASRLHE-LQ--ELLQTCVL-
-------PTEQEPSREVT-CFPLLSPGEWRKPLANG--WHRWLP-----FTCWILLGAIS
LAS-----AFF--TALYSLDLNTDQ--AT-------SWLV-----------------SMV
LSVLQNIFISQPIKVVVLTFML----------SL-----LMKRIPWLSR-----------
-EREQQTRRIL-ALAAKCSPS-PPGSRDQNNPIYRAPAT--------HAVKGKKLFKLTG
DIVAVQILFLGLLL-----STVYSGKNSNRFHLHQAVRKSFSHRFSEIKLLEDFYPWA--
----------------------------------------RHSLLPNLYGNYTGLEAEAE
PGRRP------------DGKQL--IRILPQLNVFSCKKGKE----------VICALGNVS
FTHGESFTSLFKYLDLI---CSSYPIVLAKVNAHSSSLLSFKKKLLEWYMRR--WTLIGS
V----------RVGSLPSPQ--TLEGLGWAVI-SQV------------------------
----------------------VYHLLVCYY-------AFVQGRRLRQQGWRFLTHKRNA
LDTSVVLVSFVILVLDLRQIFLHRTYMAQRRQDRDRFINFHEAVQVDSAVTHLVGILVLL
ATVQLWNLLHHDARLQVISRTLSRA---WDEVTGFLLIILLLLTGYAT------------
----------VF--HVLFGWKISDYRTFVNSVVTVVGLLMGISHYKEVIALDPVLGCFLI
-LASAILMVLVVINLFVSAILMAFGKERKSLK---TETTLLDMLLQKLSSLLGIRWHQNP
SPEK---------------------------------------------------

-----MFFQERAWLWLFIRVCIILG----HEHKVPDQ--HGKNNCYQLNRLCSSFQEAEQ
HCRGQ-GGHLANTWTQESKALIWSSLKEGTKWWVAQNLPKSDL-----PLGD----AAGS
RNLKSNHCNSVFRYSKDILLRKERCSQKHHFICQADH-FS-------NPDASNGRIEHNP
FPRR--------PKRGAKTQQKETSGNVFLLQMCVFS-----K----TTPQKT-VTS---
------------------------------------------------------------
---------------APRDPLQV------------------------TSASSAPRHSP--
-------------HVISDTS------APRNAPQMTSVTSTNRHSPQVTSVTSAPRDLPQV
TSVTSVPRD---------------PPQVTSVTSTPTHSPQATSVTSAPRDPPQVTSVTST
PRQSPQATSVTSAPTDPPQVTSVTSTHRHSPQVTSVTSIH---------------SPQVT
SHTSAPRYSPQVTSVTSVPRDPPQVTSVTSIPTHSPQATSVTSAPRDPPQVTSVTSVPRD
PPQVTSVTSTHRHSPQVTSVTSAPRDPPQVTSVTSVPRDPPQVT-------------SVT
STHR-HSPQVTSVTSAPRHSPQVTSVTSTPRQSPQVTTVTPAPR-DPPQVTLVTST----
-----------PRHSPQATSVTSVPRDPPQVTSVISALRHSPQVTSDTSAPRDQPQVTSV
TSAPRDLPQVTVTSAPRHSPQVTVPPVHGSPPGPLMTRLTSPVSTSPAGRSLADTTWSPK
EDSHSGGDTTHPQTSFQNASSQ--------------------------------------
----------------------------------------------------------VS
LE-TGSLRPTVPGLQ-AHSELQNACNILQRLKDFLPTSPTP--------AQVSVVDLLID
LSEQLLNITF-QKNKSWSFKTPSTTCFFQPVEGTVKSGKESQQTSLKNTEQV--------
---------------------------------EDMLEMFLIALGEIQKAFF-----QQS
LSPESSVTLTSS-----IATLMLSSQNTSTLPLSTYTLGGPAPLRL--RFPSAAALKELL
DKHPGMNL--------------------QIMGLAFNPFEMLDGRNTVGVIGNVL------
---LSSNYRSL---QVHDLMEDIEIMFWRNASME--------------------------
-----------------------THPTSLNASTDRFTITVNITSLEKSLIVTIEPEKPLL
M--TLYLGFQDQPDHAHFH---LDITLPRGQ--VW-QKDEEYTWLLSPESL---------
-QYGTGTYNITAVVNQSSETTLQTPFLVSVVTAVTQCY-------FWDTYNRTW---RSD
GCQVGPQSTALKTQCLCNHLTFF SADFFIVPRTVRVE-DTIKLFLHVTNNPVGVSLLASL
LGLYVILVMWAWRKDQADEQKVKVTVLADNDPSSQFH YV------VQVYTGYRRQAATTA
KV-----------------------VITLYGSEGHSEPHHL-WDPQKMVFERGALDVFLL
STRSSLG-ELHGLRLWHDNSGGSPAW--------YVS------QVIVSDMAAKRKW----
---------HFLCSCWLATDLGDCERDVVFRPAS-------RKELSSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLTCCMTLLLCDMVI-------NV-MFWKMGG
TPAKR---GRQ--KDPFTVTWSELFISVQTAAILFPIHLVIGRLFPLSQPQEILPP-LPP
IQASCPLSVACEPPSLTKVVEEL-----KETVGFLLRR----------------------
-NTHLLSEYELSSWSS---CDTNKLVKLLSSLIYSHVEDRG-CY-RLAGSHWVS-----E
NHRHFCRY---LLQVLQRLKSHLDVLGLARVHQSCDFLEAASHLQN-LQ--KLLEAQIL-
-------SREQG---DTT-SFPILSPEEGKKLESVY--LFTWLT-----STCWLLLGVIS
LAS-----AFF--IALYTLELSKDQ--AT-------SWVV-----------------SMM
LSVLQDIFISQPMKVIFLTFFF----------SV-----MMNQVPQLNK-----------
-DKEQQTKRIV-ALWAKCSSL-LPSVRDENNPIYRAPAMTSPAKRPEREWKK-NLLKLTG
DVL-VQTLFLVLLM-----TTIYSAKNSNQFFLHQAIWKSFSHHFSEIKLLEDFYPWA--
----------------------------------------NHTLLPNLYGDYRGFITDGN
SFLLGNVLLRQIRIPNAILSPV--SVQEQVKPYPQHQEDTAN-YGVGW----GPPDPNTT
-----QSDSIWHYQN--QESLGGSPIQ---G-----E--FAAYSGGGYVVRLGRKSSTAT
RVL-------QHLQQTHWLDHCTKVLFVEFVVFNANVNLFCVVTLILESTGVGPFFTSLR
LDSLTSLQIAERGFAWI-VSQVIYYLLICYY-------TFIQGRRLKRQRWRFFTRKRNI
LDTSIILISFNILGLDLWCISLHHKNMLRYHHDRDRFVNFHEALQVSSAVIYLMGFLVLL
ATVQLWDLLRHNPQFQVISKTMNKA---WDEVVGFLLIILILLTSYAM------------
----------TF--NLLFGWSISDYQSFFSSAVTVVGSLMGISNHKEVISLHPVLGFFLI
-LTSVILMGLVIINLFVSAILIAFGEERKSLK---KEAALTDMLLQKLSSLLAIRQHNPS
AEKQ---NNSS----SNLRERSSKSMSSDAEVLAPADAVGSVSGTDGNSGNTK--

-----MFFKGGSWLWLYIRTSIILG----SELNSPGP--HGQNNCYQFNRFHCSFEEAKN
YCHGQ-RGFLADIWNQEVEDLIRDFLEEGEKWWIGQNVMPLRKHQDKNYPAD----VAAH
GAPKPPSCTYLSRNLNRILSKEDKCFLRHYFICQTDD-VL-------DRDAHYERNGNDS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------YERPE------K
TKR---------------------------------------------------------
--GVAIARD---------------K-----------MPSGPGAL----------------
-----------------------SATCHHP--------L---------------------
-----P------------------------------------------------------
------------------------------------------------------------
---A-HLSK-TL----------CHPISPFPSVLQ--------------------------
----------------NI-----------------------------------TSQV---
---------------------T-ATSEASSQPLPVITQLTTPVSVTRAGQSLAETTSSPK
EAAHVNTVTSHLQVSLQNASGQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSQAVHGLQ-AHNKLQEACEFLQKLTALTPRFFKP--------AQVNLINSIIY
LSEELLRISF-LNNSGLSFKVPVTVCPFHSFNDVTKAGEGSWLESKRDTEQV--------
--------------------------------ED-ILEMSLAELGNIGEAFL-----EQD
QSPESSVTLTSS-----VATLLLSRQNTSTLPLSSYTLGHPAPVRL--GFPSALALKELL
NQHPGVNV--------------------QVTGLAFNPFKDLDHRNVVGSIGSVL------
---LSANRKLL---QVHDLVEDIEIMLWRNVSME--------------------------
-----------------------THPTSFNMSTDQLTITVNITSLEKSLIVSIDPDSPLL
M--TVYLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPEHL---------
-QHGIGTYCIRAVLSESQKGAQQMPSLVSVITAVTQCY-------YWESHNQTW---SSN
GCQVGPQSTILRTQCLCNHLTFF ASDFFVVPRTVNVE-DTVELFLRVTNNPVGVSLLAGL
LGFYVITVVWAWKKDQADMQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TTRSSLG-DLHSLRLWHDNSGISPSW--------YVS------QVIVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRQLFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKINS
TTAKR---DEQ--LGPFAVAWSELLISIHTAVILFPINLVIGRLFPLIEPQETLPL-FPP
IQASCLSDASAEPLSATMVVEEL-----KETVRFLLRR----------------------
-NTYLLSKCEQPPWSS---CDITKLVKLLSSLISSHLEGQS-CH-QQAERHWAR--VVPE
NHHHFCCY---LRRVLQRLKSHLGTLGLTQGHQPCDFLDAVSQLQK-LQ--ELLETHIL-
-------PTEQEPSREVT-SFAILSSEEGKKPISNG--LSRWLT-----AACWLLLGLTS
LAS-----AFF--TALYSLELSKDQ--AT-------SWTI-----------------SII
LSVLQNVFISQPGKVVFFTFLY----------SL-----MMSRMPRLNK-----------
-EKEQQTKRIL-ALLAKCSSS-VPGSRDKNNPVYVAPAMNSPTKRPERTLKKKKLFKLTG
DIL-VQILFLTLLM-----TAICSVKNSNRFYLHQAIRKTFSPRFSEIKLLQDFYPWA--
----------------------------------------NHILLPSLYGDYRGKNAVLK
PIHCK------------YGVQF--IFQIPCTTIYEKVEEGQL-VFSDMAVPVGIPRAC--
---------SVTSVH------PGPWGR-FPADELHKRLTSKNDSGFSYIMR---SAFFTS
V----------RLESFTSLQMS-KKGFTWSII-SQV------------------------
----------------------IYYLLVCYY-------AFKQGCRLKRQKWRFFTGRRNV
LDTSIILISFIILGLDMKSISLLRKNMARYHDDRDRFISFHEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLRVISRTLSRA---WDEVVGFLLIILILLTGYAV------------
----------AF--NLLFGCSISDYRTFFSSAVTVVGLLIGISHQEEVIDLDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---KDVALIDMLLQKLSNLLGISRPQKT
SSEQ-----AA----T-------TAMGTDTEVLDE-LP-----------------

-----MFFKGRSWLWLYMRTSILLG----SELNSPEP--RGQNNCYQLNSFHCSFEEAEH
YCHAQ-GGFLAHIRSQRVPDRIWDFLEEGKKWWIGQNVMPLKKHQDEKYPGE----TAGL
VLPLIRLCSKGDVIFPR-------------THLKLIDAFV-------DGDARYERNGNNS
HL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------PWRPK------K
TKR---------------------------------------------------------
--EVEIPRN---------------K-----------MPPGNMLLPQDLLIF---------
-----------------------FNTCHHP------------------------------
------------------------------------------------------------
---------P--------------------------------------------------
--HA-HLSK-TL----------CYPISPFSSVLP--------------------------
----------------KI-----------------------------------TAQV---
---------------------TPVTSEPSSQPLPVRTEPTSPVSVTQAGQSQTETASSPE
EGAHPNSFTSHRPASLQNASGQ--------------------------------------
----------------------------------------------------------VI
DETVGNLSRAVHGLQ-AHNKLQEACEVLQKLTALISRFSKP--------AQVHLINSLIY
LSEQFLRIPF-QSNSSLGFKVPAAICLFHSFNNVIKAGEGSWQGSKRDPEQV--------
--------------------------------ED-MLEMSLVALGNIGEAFL-----EQK
QPPESSVTLTSS-----VASLLLSRQNLSTLPLSSYTLGHPAPVRL--GFPSASALKELL
NKHPGVNV--------------------QVTGLTFNPFKDLDNRNVVGSIGSVL------
---LSANHKLL---QVHDLMEDIEIMLWRNVSLE--------------------------
-----------------------THPTSINMSTDQFTITVNVTSLEKSLIVSIDSDSPLL
M--TLFLGFQYQPNCTHFH---LNITLPKDK--VW-QKDEEYTWVLTPERL---------
-QHGIGTYYITAVLSEGQEAAQQMPSLVSVITAVTQCY-------YWDSHNRTW---SSS
GCQVGPQSTILRTQCLCNHLTFF ASDFLVVPRTVNVE-DTIILFLRVTSNPVGVSLLASL
LGFYMITVVWAWRKDQADKQKVKVTVLADNDPSAQFH YL------IQVYTGYRRRAATTA
KV-----------------------VIILYGSEGRSEPHHL-CDPQKTVFERGGLDVFLL
TSHSSLG-ELHSLRLWHDNSGLSPSW--------YVT------QVTVCDMAVKRKW----
---------HFLCNCWLAVDLGDCELDRVFIPVS-------KRELFSFRH--LFSSMIV-
--EKF-TQDYLWLSVATRHPWNLFTRVQRLSCCMTLLLCNMVI-------SI-MFWKING
NTGKR---DEQ--MGTFAVAWSELLISIHTAVILFPINLVIGRLFPLTQPQETVPR-FPP
NQVSCLLDASVEPLSVTMVVEEL-----RETVQFLLRR----------------------
-HTYLLSECEQPSWSS---CSITKLVELLSSLLSSHLEGQG-CH-QQAEHHCAL--VVPE
NHHHFCCY---LCRVLQRLKSHLGTLGLTQGHQTCDLLAAASHLQK-LQ--EFLETHML-
-------PTEQEPFREVT-SFAILSSEEGKRPISNG--LSKWLS-----SFCWVLLGLTS
LAS-----AFF--TALYSLELNKDQ--AT-------SWMI-----------------SII
LSVLQDVLISQPVKLQKFGKLR----------SL-----GVNP-----------------
-------KNRQ-TRLSKCSSS-VPGSRDKNNPVYVAPTMNSPTKHPERTLKKKKLFKLTG
DIL-VQIFFLTLLM-----TTIYSAKNSNRFYLHQAIQRTFAHRFSDIKLLQDFYPWA--
----------------------------------------NHILLPNLYGDYRGKNAVLE
LSHCK------------CRIQL--IFQIPATKTHEKVGKFYL-LTQ--------------
----------------------------AYGADKN-------ENGFSDIMRRNWSAFFTS
V----------RLESFTSLQMS-QKGFVWSVI-SQV------------------------
----------------------IYYLLICYY-------AFIQGCRLKRQKWRFFTRKRNI
LDTSIILISFIILGLDMKSISLHKKNMARYRHDRDRFISFYEAVKVNSAATHLVGFLVLL
ATVQLWNLLRHSPRLWVISRTLSRA---WDEVVGFLLIILILLTGYAI------------
----------AF--NLLFGCSVSDYRTFFSSSVTVVGLLTGISHQEEVIALDPVLGTFLI
-LTSVILMVLVVINLFVSAILMAFGKERKSLK---RQVALIDMLLQKLSNLLGIRQPQKT
SSEQ-----AA----T-------TSVGTDTEVLEDELP-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------SFS
DQHVSYG-----NNSHIHKRTKNEK--RKVEIA------RNRMT-------------SX-
--XXXXXXXXXXXXXXXXSKILCHSITPPPSVPPTITQQIP-------------------
------------------------------------------------------------
----------------------PVSSAPVSLPHSVTSEPTRSASITHAGKSLLKITSSHK
EDVHPDIFATLLQESFQNISEQ--------------------------------------
----------------------------------------------------------VI
DEIAGNFSKAIHNFQ-ARNKLQKACEVLQKLTAFLPRLSES--------TQVSLINSFXX
XXXXXXXXXXXXXXXXXXXXXXXXX--------XXXXXX----XXX--------------
--------XXXXXXXX--------XXXXXXXXAEHVLEKPFVPSGKIQETFL-----QQN
QYSGISVTLTSS-----VATLMLSSQNISTLPLSSYTLGYPAPVQL--GFPSASALEQLL
NKHPGVNV--------------------QVTGLAYNPFKDFDDKSIVGSVGNVI------
---LSSNHKLL---QVNDLKEDIEIMLWRNVSME--------------------------
-----------------------NYTTSLNMSSDNFIITVNITSPEKSLILSIEPEIPLL
M--TLYLGFQYLPNHTDFH---LNITLPKDQ--QC-QKDEEYTWVLTPEHL---------
-HYGTGTYYLRVVLDKGQEGAQQMSILFSVVTALTQCY-------FWDSYNSTW---SSE
GCQVGLQSTVLKTQCLCDHLTYFGSD FFIVPRTVDVG-DTIKLFLHVTNNPVGVSLLASL
LGFYMLTFVWAWRKDQADMQKVKVTVLADNDPDYQ FSYI------IQVYTGYRRRAATTA
KV-----------------------VITLYGSEERSEPHHL-CDL-KTVFERGGLDVFLL
RTKSSLG-ELHSLRLWHDNSGVSPSX--------XXX------XXXXXXXXXXXXX----
---------XXXXXXXXXXX-XXXXXXXXXXXXX-------XXXXXXXXXQ-LFSSMMV-
--QKF-TQDYLWLSIVTRHPWNQFTRVQRLSCCMTLLLCNMVI-------NV-MFWKISD
STAKR---DEQ--VGLLAVSRSELLTSIETGGIVFPVNLIIGHL-QMVQPQKPLPL-YSP
TQASRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------
---XX-XXXXX--X-X---XXXXXXXXXXXXX--XXXXXXX-XXXXXXXXXXXXXXXIPE
TNHHLCHY---LLRILQRLQRHLSTQDLTQADQSCNFLDAASRLQK-LQ--ELLETHIL-
-------PTEQQPGRXXX-XXXXXXXXXXXXX----------------------------
------------------------------------------------------------
-----------------------------------------------XX-----------
-XXXXXXXXXX-XXXXKCSS--VSGSRDKNNPIYIAPNMYRPVKHPERTLKKKKLFMLTG
DILXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXX-------X-XXXXXXXX--
----------------------------------------XXXXXXXXXXXXXXXXXXXX
XXXXX----------XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXPL--LSRYLCS-TKVVELDPKGLIPTGESRERLI---------------------
---------------------------------NKN------------ENLFTSLFTSLR
LDSLTSLQTSKKDIASSVISQVIYYLLVCYY-------AFVQGHRLKQQSWRFFTKRKNI
LDINIILISFV-IGLDIKRISLHKKIMAQYQADPGRFVSFYEVIKVNSAAIYLMGFLVLF
AKGQLWNLLHHNPRLQXXXXXXXXX---XXXXXXXXXXXXXXXXXXXX------------
----------XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVIALDPILGSFLI
-LTSVILLVLVIINLFVSAILMAFDKERKLLK---KEATLINILLQKFSSLLGIQLHQCK
LTSMIITGIGT----AI-KGKL---------------------------------

Query Results

"ENSGT00700000104221_0"

ENSGT00700000104221_0