ENSGT00620000087961_1 : Linker Region Query Results

----------------------------------------------------RAGKSALG
GGQLAAAAR-----------------------AAAGPQVL--------------------
--PGPGSVSRRLDPKEPLGSQRAASPTPKQAP---ATAPGHESPRETR-AQGPAGQEADG
PR RTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLP SSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCL-CQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKGEPERP-RGQG----GP-------------------------QPSPHQAE--------
---PSRATSVLGP-AQAAAPLEVGRVSPQPSL-PTKPSTAEPRPPIGEALAKSATAVPSG
SGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADSQGQPSPSKGQPKIVFSDASK
EAGSRPPGSGTGPG------PAP--GAKTEPG----AR----------------------
------------TGPG----SGPGALARTAGTTSPKHG-----KTEHHA-VPKAAAKPKT
MPKEKA-TCPLCQAEL-NVGGKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRL LEGSLGEPTPPPPVPTSQQPAAGAPHRAAGTAPL-QKGPPAPGQPSGPLPAKASP
LPAKAS---------------------PLPAKTSPQAKPPRVSEPSR TPS---------S
AQEKKAGVPTKAEPVQKPPPETTQPP---GT--PKAKSGARRTEPATPVSK-AVP-EAP-
--------------------------------------------------KGGEAEELVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVVVQHEVEQLDSAGVTGPRPASSSELH
KVRS-GMRPLLEAQGLAPSGE-QSKPLTS---SSSEEQKRRPHSLSIMPEAFDSDEELED
ILEE-EEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQAPARA-AEL
TDEEFMRRQILEMSAEEDNLEEE-DAVT---SGHGLAKHSTQKGG---RPRAEPSQEPV-
-TLPKRRLPHNATTGYEELLSEVGPAEAPD-GSVALQGGLRRFKTIDLNSTGSYGHELDL
GQGPDPGLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLX-----------SRLYKSGSEYNLPTFMSLYSPTEMPSSGSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPQAGF-SQPMGP----RGQGSFEYQDTPDRDYS-R
AAQPASDSTSAG--LGTAVYEEILQTSQSIARMRQASSHDLPFAEDK---------KEKQ
FLNAESAYMDPMKHNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LRLHSSPVSPSS-APKEVGMPLSQGPGAP-ATTALAPCPSSLPHGYMTPSSP
PGSERSPLPSAIVHSYGQTPTTANYGSQTEELPPTPSGPAAGGRAAREKSFVS------D
AQSSRAYSYFAGSSPPLSPSSPSESPTFSPGRL--G----PRATAEFSTQTPSPAPASDM
PRTPSASTPTPMVAQGTQTPNRPSTPRQAWQQSPQEAPFMVITLGSDASSQTRMVHASAS
TSPVCSPTGSQP--TAHSYSQTTPPSVAQLPSDPPGP-SGLPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TVASSVLMAQPKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLANQVAPLARRDVLITPMGTAQSVGLKPG-LVPEPSAEP
HRATPAELRPHG---VPGARKPHTVVVQVGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSASEKSAADG--APPGQSTSPFYGHRDPEHPEPPSY
RAQGLVGPGPHEEQRPYPQALPG-LYSSMSDTNLAE-GLNYHAHRLGQLFQGPSRDSAVD
LSSLH-SYSL-FADGRFLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RRDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GGGPDLMQY-QPQP
GPGL-----SAPQGLAPLRPDLLGNPTFPEGHSSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASLLRPMVRG-SMYRPYASGGVTAVPLTSLTRL
PVIAPRIPLGPTGLYRYPAPSRFPPVSSVQPVEGPVYLGKPAAAKAPRAGGPP-------
----------RPELLSGAPREEPLATATPA-AIKEAAAAP----------TPLTAQKPPG
DAA-PGPGGGALSRPAQEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKHRQKAPFPAAC-EAPGRGAPPT--------AAELAQNGQYWPPLTHT
AFI-AVAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRS-GMKKRHSMPRLRDA
CEPEPGP-EPCMVKRIADSSVQTDDEDGESRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSSSDSKHDATASSATT--------ATALRATSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGHGESLACQTEPDAQ-APGVAGPQL
VGPAAISPYLPGIQIXXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EVHLPLASQP-PPQMYAASLLQWLAGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX----X------XXXXXXXXXXXXX----X-XX---------XXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXX----XXXXXXXXXXXX-XXXX-XXXXXXXXXXXXXXX
XXXXX-------XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXGG----HHRGMESNGRP--------ASAHYYSDNDYRH
GARAEKYGPGPVGPKHPSKGLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--SAVSSSLGSRGRKFQDSITYGLKKNVYEQQKYYGLSSRDSAEDDDRIYGGGSR-S
RAASAYSGEKLSSHDVSGRGKGYERE------------------REAVERFQKAGPKPTS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----QAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHMYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSSS--SSQKRGSARHSYHDYD-EPPEEGLWPHDEGGPGRHTSTKEHRH
HSDHGRHS-----GRHSSE-------------------EPGRRAAKPHVRDSGRHEARPH
PQPGPAPAMQKK--------GQPG Y--------PSSAEYSQPSRTPSAYHHASDSKKGS-
RQAHPGPSAL------QPKPEPQ--PQP-QGRQAPPGSQQSQPPLSRQGPSVAASRQPQT
QQQQQQ---------------------LP---SQQAPSQARLQQQG--------------
QPAARGPTPAA-SQPAGKPQ-P GPTAAAGPQP--------AGP-----------------
----PRAEQANGSQ-GSA--------------KAPPQGKPPQAQPPQGPGPAGVKA---G
ARSGGTPGAPAGQTGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGP------GP--GPGAGQPPSALA----G
GGQLPAAGVA-------RAAGPLAPGLGQVPGPGP----G--------------------
--PGPGSVSRRLDPKEPLGSQRATSPTPKQASAASATAPGRESPRETR-AQGPPGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----AT-------------------------QSGPRQAE--------
---TARATSVPGP-TQATGPPEVGRVSPQPPV-STKPSTAEPRPPVGEAQGKSATTVPSG
LGAGEQP-QEGLTGKLFGLGASLLTQASTLMSV-QPEADSQGQPSPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PAP--GAKTEPG----AR----------------------
------------TGPG----PGPGALAKTGGTASPKHG-----RAEHQA-ASKAAAKPKT
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLAEKTEWLCLNC
QTKRLLEGSLGEPAPM-PLPTSQQPPAGVPHRAAGPAPPKQKGPQGLGHPQAT---KASP
QAAKASPQAA-------K-------ASPQATKASPQAKPLRASEPSKTSS---------S
AQEKKTGIPVKAEPVPKPPPETTVPP---GT--PKAKSGVKRTEPATSVIK-PVP-EAS-
--------------------------------------------------KGGEAEEPGS
KPHSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQDVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLETQAVAPSGE-WSKPPRS---SAAEDQKRRPHSLSIMPEAYDSDEELGD
ILEE-EDDSLAWGHQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--EL
TDEEFMRRQILEMSAEEDNLEED-EAAV---SGRSLAKHSTQKGSA--RARPESSQESV-
-AVPKRRLPHNATTGYEELLSEEGPAEPTD-ASGALQGGLRRFKTIELNSTGSYGHELDL
SQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSETETLD-GGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEDMMRKAELLQ-RQQGQVAGARGPHGGP-AQPTGP----RGQGSFEYQDTQDHDYG-R
AAQPAAESTPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPVSSSL-ASKEVGMTFSQGPGTP-ATTIMAPCPSSLPRGYMTPPSP
AGTERILSPSSTAHSYGQTPTTANYGSQTEELPQAPSGPPAGGRAPREKPVSGADAEAGA
PQSSRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----PRATAEFSTQTPSLTPSPDT
PRSPGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRTVHASAS
TSPLCSPTDTQP--TSHSYSQTTPPSASQMPSEAAGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDILITQVGTAQSVSLKPG-PVPEPGGEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVADA--TLPSQSSGPFYSPRDPEPPEPLTF
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRIGQLFQGPGRESAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPSDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GGAPDLVQY-QPQH
GPGL-----SAPQALAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQG-TTVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLSSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPVASSIPPAEGPVYLGKPAAAKTSGAGGPP-------
----------RPELPAGAAREEPLSTTAP-AVIKEAPVAPTPV--------PAPGQKPPG
DVAAAGGGGGVLSRPGAEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPPTC-EAPSRGPPPA--------ATELAQNGQYWPPLTHP
AFI-AMAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWDAGRS-SIKKRHSMPRLRDA
CEAESGP-EPCTVRRIADSSVQTDEEEGEGRYILTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASS--A-------AATSARAMSSIGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
IGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFMPDSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHQDYLSDSELNQLR
LQGC----T------TPAGQYVDYPAST----A-VP---------ATPSGPTAFQQPRFP
PAAPQYPA-GGSGPTQNGFPAHQ----VPTYTGPSTYPA-PTFPPGTSYPAESGLPSQQA
FHPTG-------HYAAPSPMPTTQSTLYPAQADSRAPHQKPRQTSLADLEQKVPTNYEVI
TSPAVTMSSAPSETSYSSPAV-SS-SYEQGKAPELPRGSDRSTVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTATDSQRLEPLGPGGVSGRPGKE-PGEPAAIEGSTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP--------AGTHYYSDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPT--PTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDDRMYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSTAHGRARPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREESYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDMGRHETRPH
PQASPAPAMQKK--------GQPGY--------PSSADYSQPSRAPSAYHHASESKKGS-
RQTHSGPTAM------QPKAEPQSQPQM-QARQAAPGPQQTQSPSSRQMPPGTASRQSQM
QQQ------------QQPQQQQGVVQQA----PQQTPSQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPTTAPGPQP--------AGL-----------------
----PRVEQASSSK-AAA--------------KAPQQGRAPQAQPAPGPGPTGVKP---G
SRPGGTPGAPTGQTGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SVPRRLDPKEPLGSQRAL-PPPRQPS---PPTPGRESPREPR-AQGPEGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------GLSPAHSPAKQPL
GKPEQERA-RGPG----GP-------------------------QPGPRQAE--------
---TARATSVPGP-APAAATPEVGKVSPQPSL-PIKPSTAEPRPPAGEAPAKSATAAPSG
PGAAEPT-QEGLTGKLFGLGASLLTQASTLMSA-QPEVDSQGQPAPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PGPTTGAKTEP-----------------------------
---------------G----SGPRAQ-RTGGTTSPKHG-----RTEHQAT-SKAAAKPKT
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLP-LPTSQQPPAGAPHHTAGTAPPKQKGAWGLSQPSGPPPAKATP
LPTKAS---------------------PLPTKASPQAKPARASEPSRTPS---------S
AQEKKTGVPAAAEPVPKPPPETTLPP---GT--PKAKAGVRRTEPTTPITK-AVP-EAP-
--------------------------------------------------KGGETEEPGG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGIV-RQEMEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQGPAPSGE-RSRPPS----GSAEEQKRRPRSLSIMPEAFNSDEELEE
ILEE-EEDSTEWGRRGEQQDAAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-ADL
TDEEFMRRQILEMSAEEDNLEED-EAAP---AGPGLAKHASQKGGP----RPPPE-----
-CLPKRRLPHNATTGYEELLSEGGPVEDVDGTAGALQGGLRRFKTIELNSTGSYSHELDM
GPGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSPEEVS--
-DPRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEAPE-GAPSRLYKSGSEYNLPTFMALYSPTETPSGSATTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPHGGP-PQPTAP----RAQGSFEHQDSPDRDYGG-
VAQPAAEGTPAG--LGAAVYQEILQTSQSIARMHQASSRDLAFAEDKK--------KEKQ
FLDAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFATSS--TSDSSGGRVIPDVRVTQ-HF
AKEPQDP-VKLHSTPASPSS-TSKEVGIGFAQGLGAS-ASMAVTAGPAGLPRGYMAPTSP
AASERSPSPSFTGHGYEQSPATANYGSQTEELPQAPRGPAVSGRAAREKPLGMSEGESGP
PQTSRGYPYFVSSSPPLSPSSPSESPTFSPGKL--G----PRATVEFSTQTPSPTPASDT
PRSPGAPAPTPTVAQGTQTPHRPSTPRLVWQQPSQDAPFMVITLASDASSQTKMVHASAS
TSPVCSPVDTQP--TTHSYSQTTPPSGSQ-PPEPPGP-PGFPRA----------------
--PNAGADGPLAVYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTTPYRGGPRG--
----------RPRETKFARYNLSNQVAPLARRDVLITQVGPGQSVGLKSG-PVPEPGTEP
HRAAPTELRSHA---LPGARKPHTVVVQVGEGAAGTVSTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGSFRAAPSAPERSVAEV--APPGQSSGPFYSPRDPEPPEPPTY
RAQVIGGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRFGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLMQY---QP
QPGL-----SAPQGLAPLRPGLLGNPTFPEGQGSPGNLAQYRPTAGQA-AAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYPPGGVAAVPLASLTRM
PVIAPRIPLGPTGLYRYPVPSRFPTPASVPPTEGPVYLGKPAAAKASGTGGPP-------
----------RPELPAGAAREEPLSTAPPAAA-KEMGA----------APALGAGQKPLG
EA-TPGGGGGALGRPGLEKEDALPEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTLKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQ----QQLEEQKQRQKPPFPMAC-EAPGRGPPPA--------VPELAQNGQYWPPLTHA
AFI-AV--PEGSGQPR-EPMPHRGLPSSASDMSLQTEEPWEGGRSGGLKKRHSMPRLRDV
CEPESAP-EPCGVRRIADSSVQTDEEDGEGRYLLTR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASS-AA--------APATRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAVTDPKVEIVRYISAPP---------------------------
-----TSPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQLLV
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSAFRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFPLYQHQGGLGSQVSAPPPNGLVRKVKRTLPSPPPE
EAHLPLAGQAAPPQLYAASLLQRGLVGPTAVPTTKASLLRELDRDLRLGEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-SGRDYPPLRGLSEHRDYLSDSELNQLR
LQGC----A------TPAGQYAEIPVTAA---AAPP-------------------PSPLP
PPAPLSPA-GSAGPTQNGFAAHQ----APTYPGPSTYPA-PAFPPGASYPSEPGLPSQQA
FRPPG-------HYTAQTPLPTTQTTLFPAQADSRAPHQKPRQTSLADLEQKVSTNYEVI
ASPVVAMSSAPSETSYSSPGPTASSSYEQGKAPELPRASDRSAVSLSPAPIYSSDSHYTS
LEQTVPRNYVMIDDISELTKDSASAAPES-QLEPLGPS-SSGRPAKE-PGEPGILEGSAL
PCCYTRGEEESEEDSYEPRGKSGH-----HRGVESNGRP--------ASTHYYSDSDYRH
GTRADKYSPGPAGPKHPSKSLAPAAVPSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--SAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPAEEDDRVYGGSSR-S
RGAPAYSGEKLSSHDFGGRAKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRTRPPMRSQASEEESPVSPLGRPR----PAA----PP-GGASPPFCPS-HSMPD
VQEHV-KEGPRSHSYKRDEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHAGE-------------------EPSRRAAKPHVRDVGRHEARPH
PQPSPAPAVQKK--------GQPGY--------PSSAEYSQPSRAQSAYHHSSESKKGS-
RQAHPGPVAL------QPKLES--QPQP-QGRQAAPGPQPSQPPPSRQMPSATASRQPQT
QPQPERRPSDSHR---------------P---PAVRTRHMEALQGGC-------WDSSLD
RPWVQGWAE--------RMD-S----SSPVFC--------VL------------------
---QPRAEQANSSK-GTA--------------KAPQQGRPPQAQPPPGPGPAGVKA---G
AKPGGTPGAPAGQPGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------DPKEPSGSQRAASPTPKQAS---ATAPSRESSRETR-PQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVTT-LCAACLCVSASKR----------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------L-------------------------
---------------------------------------------------E--------
------ALSL------------IEA---------------------------------VG
LADA----------------------CG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PV-RSPLCAGLA-PVGP--------------------------RLLE--MFTCA--
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------SVP-----
------------------------------------------------------------
----------------DGWV----------------------------SCTEWHQSSKLH
KVGS-SMQPLLEAQAVAPSAE-WSKLPCR---ITSEEQKQRPHSLSIMPEAFDSDEELED
ILEE-DEDSLEWGHQQEQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPLRA-AEL
TDEEFMRQQILEMSAEEDNLEED-DTAA---SGHGLAKHGTQKGSSGTRPRPES------
----ARRLPHNATTGYEELLTEGGPTESTDSGGGVLQGGLRRFKTIELNSSGSYSHELDL
GQGPDASLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-SGPSRLYKSGSEYNLPTFMSLYSPTEMPLGSSTPPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVGGGHGPHGGP-SQPTDP----RSQGSFEYQKAPDHDYG-K
TAQPVPEGTAAS--LGTAVYQEILQTSQSIARMQXXXXXXXXXXXXXX--------XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXRGYSYFTGSSPPLSPSSPSESPTFSTAKL--G----PRATVEFSTQTPSPTPSLDM
PWSPGTPTSTSMVAQGTQTPHRPSTPHLVWQQTSHEAPFMVITLASDASSQTGVVHASAS
TSPLCSPTDSQP--TPRSYSQTMPPSVSQLPSE----PPDFPRA----------------
--PSAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRSGSRG--
----------RPXXXXXXXYNLPNQVAPLARRDVLITQMGTTQSISLKPG-PVSEPSAEP
HRAIPAELRAHA---LPSARKPHAVVVQMGEGTAGTVTTLLPEE-PASALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSAPAKSMADT--ALPGQSSGPLYSSRDPETSEPPTY
P-QGIVGPRPHEEQRPYPQGLPGRLYSSMSDTNLAEVGVNYQAHRLGHLFQGPRRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLIHPLPMRRYSSVSNIYSDHRFGP
RGEAGGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHASG--GTGPDLVQY-QPQH
GPGL-----SAPQGLDPLRPGLLGNPTFPEGHPSPRNLAQYAPVASQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRS-GIYRPYVSGGATAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPISSSVPPAEGPVYLGKPA-AKAPGSGPPA-------
----------RPELPAGAAREEPQSTAPPA-VVKESVAAA--------ASAPLPGQKPPG
DGAAAGGGSVVLGRPGHEKEEASQEERQRKQQEQLLQLERERVELEKLRQMRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPGRGPPPA--------ASELAQNGQYWPPLTHT
AFL-AVAGPEGPGQSR-EPMLHRSLPSSASDMSLQTEEPWEAGRS-GIKKRHSMPRLRDA
CEPESAP-EPCVVRRIADSSVQTDDEDGEGRYLLTR-RRRTRRSTDCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------ASTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDGQ-VQGMAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPLESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTTDSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPTTIPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRECSPLRSLGAHRDYLSDSELNQLR
LQGC----T------TPAGQYSGFPASA----A-AP---------ATTSAPTAFQQPRFP
PPAPQYTA-GNIGPTQNELLAHQ----APTYSGPSMYPT-PAFPPSSTYPTEPGLPNQQA
FCPSG-------HYAAPTPMPTTQSTLMPIPADSRA-SQKPRQTSLADLEQKVPTNYEVI
TSPVVAMSSAPSETSYSGPAV-SS-SYEQGKTPELPRASDRGNVSQSPVPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDS--TVPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYTRGEEESEEDSYDSRGKAGH----HHRSMESNGRP--------TSSHYYSDSDYRH
GARVEKYGPGPVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--SAVSSNLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGGSSR-S
RIASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGSKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PTGGT-LPP-GDTCAQFCSS-HSMPD
VQEHV-KDGPRAHSYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWSHDEVGPGRHAPAKEHRH
HSEHGRHT-----GRHAGE-------------------EPGRRTAKSHVRDSGRHEGRPH
SQPSSAQAMLKK--------GQPGY--------PSPTDYSQPSRAPTAYHHTSDSKKGS-
RQAHSGPVVL------QPKPEPQAL--P-QGRQAAPGLQQSQPPPSRQMASGAALRQPQM
QQQQQQQ--------QQQQQQPGLGQQP----PQQALSQARPQQQS--------------
QPAARGPASGA-SQPTGKPQ----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------VSRRLDPKEPLGSQRTTSPTPKQAS---ATAPGRESPRETR-AQGPSGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----AT-------------------------QSGPHQAE--------
---TARATSVPAP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPVGEAQGKSATTVPSG
LGAGEQP-QEGLTGKLFGLGASLLTQASTLISV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRLPGSGPGPE------PTS--GAKTEPG----AR----------------------
------------TGPG----SGPGALAKTGGTASPKHG-----RAEHQVAASKAAAKPKT
TPKERA-TCPLCQAEL-NVGSRGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPM-PLPTSQQPPAGVPHRAAGAAPLKPKGPQGLGQPSGSLPAKASP
QAAKASPQAA-------K-------ASPQAAKASPQAKPLRASEPSKTSS---------S
AQEKKTGIPVKAEPVPKPPPETTVPP---GT--PKAKSVVKRTEPATPVTK-PVP-EAP-
--------------------------------------------------KGGEAEESAS
KPYTQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQDVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQAVAPSAE-WGKPPRS---SAVEDQKRRPHSLSIMPEAFDSEEELGD
ILEE-EDDSLAWGHQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPART--EM
TDEEFMRRQILEMSAEEDNLEED-DTAV---PGRGLAKHSTQKGSA--RPRPESSQES--
----ARRLPHNATTGYEELLSEGGPAEPTD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEQSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEEMREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPPRLYKSGSEYNLPAFMSLYSPTEDPSGSSTTPSSGRPLKSAEE
AYEDMMRKAELLQ-RQQGQVAGARGAHGGP-SQPAGS----RAQGSFDYQDTQDRDYG-R
ASQPAAEGTPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
YLNAESTYMDPMKQNGGPLTPGTSPTQLAAPVSFAPAT--SSDSGGGRVIPDVRVTQ-HF
AKEPQDS-LKLHSSPVSPSL-ASKEVGMTFSQGPGTP-ATTVIAP-------WYMAPTSS
AGSERSPSPSSAVHSYGQTPTTANYGSQTEELPQAPSGPTVGGRAPREK---GTDAEVGA
PQASRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----TRATAEFSTQTPSLTPSSDI
PRSPGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASAS
TSPLCSPTDTQP--TSHSYSQTTPPSASQMPSEPGGP-PGFPRA----------------
--PSAGADGPLALYGWGSLPPENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPMP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPRESKFSRYNLPNQVAPLARRDILITQMGTAQSVSLKPG-PVPEPGGEP
HRAVPAELRSHA---LPGVRKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVADA--ALPGQSSGPFYSPRDPEAPEPLTF
RAQGVVGPGSHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRLGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GGGPDLVQY-QPQH
GPGL-----NAPQGLAPLRSGLLGNPTFPEGQASPGNLAQYGPAASQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPIASSIPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEPPAGAAREEPLSTTAP-AVIKEAPAAPAP--------APPPGQKPSG
DAAAAGGGSGVLSRPGVEKEEASQEDGQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AMAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDV
CEPESGP-EPCTVRRIADSSVQTDDEEGEGRYFLTR-RRRTRRSADCSVQTDDEDNADWE
QPVRRRRSRLSRHSDSGSDSKHDATASS--A-------AATAARATSSIGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKPFMADSTLRQQTLPRPV
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYTA-GSTGPTQNGFPAHQ----ASTYTGPSTYPA-PTFPAGTSYPAEPGLPSQQA
FHPTG-------HYAAPTPMPTTQSTPFPVQADSRALHQKPRQTSLADLEQKAPTNYEVI
TSPAVTMSSGPSEASYSGPAV-SS-SYEQGKAPEHLRGSDRSSVSQSPAPTYPSDSHYTS
LEQSVPRNYVMIDDISELTKDSTPTAADSQQLEPLGPSGVSGRPGKE-PGEPAVFEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----YRSMESNGRP--------ASTHYYSDSDYRH
GARAEKYGPGPMGSKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPT--PTVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSR-S
RGASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDAGRHETRPH
PQASPAPAMQKK--------GQPGY--------PGSADYSQSSRTPSAYHHASDSKKGS-
RQAHAGPTAL------QPKPEPQSQPQM-QGRQAAPGPQQSQSPSSRQMASASRQ----P
Q-QQQQQQQQQ--QQQQQQQQQGVGQQA----PQQAPSQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPSTAPGPQP--------AGL-----------------
----PRTEQASSSK-AAA--------------KAPQQGRAPQAQPAPGPGPTGVKP---G
ARPGGTPGGPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

MPYQLALNSLASRWPSDGGSK-L-RIFSCQSDPGALRQKLPGQSPAQARPPH-------C
SQQVMPAFTPMTDC--LRC---------------ISNSHF--------------------
--QCHFSTSRRLDPKESLGSQRAASPTPKQAS---ATTPGQESPRETR-AQGPAGQEADG
PHRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSHQGE--------
---MARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
---------------------LPTKASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGHGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTSP----RGLGSFEYQDTADRDYG-R
AAQPVAEGTPAS--LGAAMYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
SGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPIGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMIHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAIGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAVREEPLPTTTPA-AIKEAAGAPAP--------APLAGRKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESVA-EPCMVRRITDSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTSVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FHPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGSAV-SS-SYEQGKVPEVPRASERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
QQQ--------------QQQQQGLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG-PLPPGG--AGPSPGPGPGPGPGAGKPPSAPA----G
GGQLPAAGAA-------RGTAGP---PVPD--PGPGPGPG--------------------
--PGPGSTSRRLDPKEPLGSQRAPSPTLKQAS---ATTPGHESLQETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSMLCPICKTSDLTSTPSQ
PNFNTCTQCHSKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPQ
GKPEQERS-RGPG----GP-------------------------QPGSSQAE--------
---TARATSVPGS-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATTVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFSDASK
EAGPKPSGSVPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALAKTGGTTSPKHG-----KAEHQVASKAAA-KPKT
MPKERA-TCPLCQAEL-NMGSKSPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVRAPHHASGTTPLKQKGPQGLAQPSGPLPAKASP
LPTKASPLPTKASLLPTKASPLPTKASPLPTKASPQAKPLRASEPSKTPS---------N
ALEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVIK-AIP-EAP-
--------------------------------------------------KGGEVEDLVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPCPPSPSEIH
KVGS-SMRPLLEAQGLAPSGE-RSKPPCS---GTGEEQKQRPHSLSITPEAFDSDEELED
ILEE-EEGSVEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DAAT---SGHGLAKRGTHKGGP--RPRPEPSQEPV-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAPGARGPHGGP-SQPTGP----RGPGSFEYQDTADRDYG-R
ATQPATEGTPAS--LGAAVYEEILQTSQSIVLMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTS--TSLDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEAGMPLSQGLGTP-ATTAVAPCPARLPRGYMTPASP
AGSERSPSPSSTGHSYGHSPTTANYGSQTEDLPQVPSGLAAAGWAAREKPLSASDGEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKL--G----QRATAEFSTQTPSLAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHSYSQTTPPSVSQLPPEPPGL-PGFPRA----------------
--PSAGVDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKLARYNLPNQVAPLARRDVLITQMGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PTGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSAPEKSMADA--APPGQSSGPFYGPRDPEPPEPLTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPIPIRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QSQH
GPGL-----SAPQSLAPLRPGILGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPVEGPLYLGKPAVAKASGAGGPS-------
----------RPEMPAGAAREEPLPTTTPA-AIKEAAGAPAP--------VPLTGQKPPA
DA-APGGGTGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWETSRS-SIKKRHSMPRLRDA
CEPESAP-EPCVVRRIADSSVQTDDEDGEGRYLLTR-RRRARRSTDCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATALSST--------AAATARAMSSVGIQTISDCSVQ
TEPDQMPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGIAGPQL
VGPTAISPYLPGIQIVTPGPL----------SRFEKKKPDPLEIGYQAHLPPESLSQL-M
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-APQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPSGQYVDFPATAA---A--P---------TTPSGPTAFQQPRFQ
PLAPQYTA-GSGGPAQNGFPAHQ----APTYPDPSTYPAAPAFPPGTSYPAEPGLPNQQA
FRPTG-------HYVGQTPMPTTQSTLFPVPTDSRAPPQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPTV-SS-GYEQGKVPELPRAGDRGSVSQSPAPTYPSDSHYTN
LEQNVPRNYVMIDDISELTKDSTSTVPDSQRLEPMGPG-SSGRSGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----HRSMESNGRP--------ASTHYYGDSDYRH
GARTEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPL--PAVSSSLVSRSRKFQDEITYGLKKNVYEQQRYYGMSSRDAVEEDDRIYGGSSR-S
RAPSTYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPSRHSYHDYD-EPLEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAP------QSKAEPQAQPQL-QGRQAAPGPQQSQPPSSRQIPSGAASRQPQM
QQQQ-----------QQQQQQQSLGLQP----PQQAPTQARLQQQS--------------
QPTTRGSAPVA-SQPAGKPQ-PGPTTATGPQP--------AGL-----------------
----PRAEQTNGSK-GTT--------------KAPQQGRAPQAQSTPGSGPAGVKA---G
ARPGGTPGAPASQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

MPYQLVPKSFGKQMAFRWGQQS---------DPMRTGGHWGRRSQGSLLH---------R
QLWSGLC-------GALRESALP---PVH----------F--------------------
--QCHFSISRRLDTKEPPGSQRAASPTPKQAS---ATAPGRGSPRETR-AQGPAAQEADG
PRRTLQVDSKTQRSGRSPSVSPDRSSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPA----GP-------------------------QPGPRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPL-PSKPSTAEPRPPAGEALAKSATAVPSG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQPAPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PAP--GAKTEPG----TR----------------------
------------TGLG----SGPGALPKTGGATSPKHG-----RAEHQVASKT-AAKPKT
MPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPMPLPTSQ-QPPAGAPHRAAGTAPLKQKGPQGMGQPSGPLPAKAS-
--------------------PLPTKASPLPTKTSPQAKPPKASEPSRTPS---------S
AQEKKTGVPAKAEPVPKPPPEATPPP---GT--PKVKSGGKKAEPATPVIK-AVP-EAP-
--------------------------------------------------KGGESEELVG
KPYSQDVSRSPQSLSDTGYSSDGVSSSQSEITGVV-QHEVEQLDSAGVTGPRPPSPSEIH
KVGS-SMRPLLEAPGLAASGE-RSKPPCS---SANEEQTRRPHSLSITPEAFDSEEELED
ILEE-EEDSLNWGRRREQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLSEEGPAEATS-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-SGPGRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSVRPLKSAEE
AYEEMMRKAELLQ-RQQGQVAGARGPHGGP-SQPTGP----RVQGSFEYQGAPDPDYG-R
TAQPASEGTPSS--LEAAVYQEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
YLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTS--TSSDSSGGRVIPDVRVTQ-HF
AKEPQEP-LKLHSSPASPSP-APKEVGTSFSHGPGTP-ATTAVAPGPAGLPRGYMTPTSP
AGSERSPSPSSAGHSYGQSPTTANYGSQTEELPKAPSGPAAGGRAAREKALSGSDSEGAT
PQPSRAYSYFAGSSPPLSPSSPSESPTFSLGKL--G----PRATAEFSTQTPSPALASDM
PRSPGTSTPTPMVAQGTQTPHRPSTPRLVWQQSSQESPFLVITLASDASSQTRMVHASAS
TSPLCSPTDAQT--TTHSYSQTIPPGVSQLPPEPPGP-PGFPRV----------------
--PSAGTDGPLALYGWSALPAENISLCRISSVPGTSRVEPGPRLPGSAVVDLRTAGKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTTPHRGGPRG--
----------RPREPKFARYNLPNQVVPLARRDVLITQMGTAQSVGLKPG-PVPEPAAES
HRATPAELRSHA---LPGARKPHTAVVQMGEGTAGTVTTLLPEE-PVGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSVPEKSMADV--VPPGQGSGPFYGPRDPEPPEAPTY
RAQGVVGPGPPEEQRPYPQALPGRLYSSMSDTNLAEAGLNYHAHRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGQ
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGS--GGPDLVQY-QPQH
RPGI-----SAPQGLAPLRPGLLGNPTFPEGHPSPGNLTQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPTSVLRPMVHG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYHAPSRFPIASSVPPAEGPVYLGKPAAAKAPGTGGPP-------
----------KPELPAGAAREESLSTTTPA-AGKEAAGAPAP--------SPLTAQKPPV
DA-APGGGSGALSRPGLEKEEASQDERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPSRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AVAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-EPCVVRRIADSSVQTDDEDGESRYFLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSST--------ATATARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGRGESLACQTEPDGQ-TQGVVGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-PQQLYAASLLQRGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGHDYPPLRGLGEHRDYLSDSELNQLR
LQSC----T------TPAGQYVDFPATAA---A--A---------ATPSGPAVFQQPRFP
PPAPQYTA-GSGGPTQNGFPAHQ----PPTYPGPSTYPG-PAFPPGTSYPAEPSLSNQQG
FRPTG-------HYAAQTPMPTTQSTLFPVPADSRVPHQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-SYEQGKAPELPRASDRSSVSQSPAPTYPSDSHYSS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPS-SSGRPGKE-PGEPGVLEGSTL
PCCYVRGEEESEEDSYDPRGKIGH-----HRSMESNGRP--------ASAHYYSDSDYRH
GARAEKYGPGPVGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSTRDTVEEDDRMYGGSSR-S
RVSSVYSGEKLPSHDFSGRGKGYDRE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPMGRPR----PAGGP-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKRE-EYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----SRHTGE-------------------EPGRRAAKPHVRDPGRHEARPH
PQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRVPSAYHHASDSKKGS-
RQAHSGPAAL------QPKPEPQAQPQL-QGRQAAPGPQQPQPPSSRQMPSGAQQQQQQ-
--------------Q--QQQQQGLGLQP----PQQALSQARLQQQS--------------
QPTARGPAPAASQQPVGKPQ-PGPTTAAGPQP--------AGP-----------------
----PRAEQTNGSK-GMA--------------KAPQQGRAPQAQPTPGPGPAGTKA---G
ARPGGPAGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------KPPSAPA----G
GGQLLTASA-------ARATAGP---PVPG--PVPGPGPG--------------------
--PGPGSISRRLDPKEPPGSQRAASPTPKQAS---TTAPGRESPRDTR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------GLSPAHSPAKQPL
GKPEQERS-RGPG----VP-------------------------QPSPRQAE--------
---TARATSVPGP-AQAAAPSEVGRVSPQPPL-STKPSTAEPRPPAGEAPGKSATAVPSG
LAAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADSQGQPAPSKGAPKIVFSDASK
EAGPRPPGSGPGPG------PAP--GAKTEPG----AR----------------------
------------TG---PGP-GPGALTKTGGTTSPKHG-----RAEQQVASKA-AAKPKT
MPKERA-TCPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPMPQPTLQ-QPPAGAPHRAAGTAPPKQKGPQGLGQPSGPLPAKASP
LP---------------------TKASPLPTKASPQAKPLRASELSKTPS---------S
AQEKKTGGPTKSEPVLKPTPETTPPP---GT--TKVKSGVRRAEPATPVVK-AVP-EAPA
--------------------------------------------------KGGEAEELVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEMEQLDSAGVTGPCPPSHSEIH
KVGS-SMRPLLETQGLAPGSE-RSKPHCS---STAEEQKQRPHSLSITPEAFDSDEELED
ILED-EEDSLEWRHRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARG-AEL
TDEEFMRRQILEMSAEEDNLEEE-DTAT---SGHSLTKHGTQKGGP--RPRPESSQELA-
-ALPKRRLPHNATTGYEELLSEGGPEEATD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQDPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEGLD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVAVSRGPHSGP-TQPTGH----RGQGSFEYQDTADPDYS-R
ASQPASEGTPTS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTS--TSSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEVGMSFPQVPGTP-ATTAVAPCPARLPRGYMTPTS-
TGSERSSSPSSTSRSYGQSPTTAHYGSQTEELPQAPSGPAAAGRVAREKPLGGGDGEGST
PQPSRAYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPASDM
PRSPSAPTPSPMVAQGTQTPHRPSTPRLVWQESSLEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTDTQP--TTHSYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREPKFARYNLPNQVAPLARRDVLITQMGTAQNVGFKPG-PVPDPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLIPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSMADA--APPGKSSSPFYGPRDSEPPEPPTF
RAQGVVGPGPHEEQRPYPQSLPGRLYSSMSDTNLAEAGLNYHAHRIGQLLQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYSS
RGDAVGFQETSLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QSQH
GPGL-----SAPQGLLPLRPGHLGNPTFPEGHPSPGNLAQYGPAAGQG-PAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRM
PVIAPRVPLGPTGMYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPP-------
----------RPELPAGPAQEEPLSTTTPA-AIKEVAGAPAP--------APPAGQKPLG
DA-APGGGSGVLSRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPPA--------ATELAQNGQYWPPLTHA
AFI-AVAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEHWEAGRS-VIKKRHSMPRLRDA
CEPEAGP-EPCVVKRIADSSVQTDDEDGEGRYLLPR-RRRPRRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDTTVSS-T--------ATAAVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-AQGVAGPQL
VGPTAIGPYLPGIQIITPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNNLVRKVKRTLPSPPPE
EAHLPLTGQA-PSQLYAASLLQRGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-SGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPTGQYVDFPAAAA---A--P---------ATPSGPTAFQQPRFP
PPASQYTA-GSAGPTQNGFPAHQ----APTYPGPSMYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAAQTPMPTTQSTLFPATADSRAPHQKPRQTSLVDLEQKVPTNYEVI
ASPIVAMSSAPSETSYSGPAV-SS-SYEQGKPPELPRASDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSAVPENQRLEPLGPG-SSGRPGKE-PGEPGALEGPTL
PCCYARGEEESEEDSYDPRGKVGH-----HRSMESNGRP--------TSAHYYSDSDYRH
GARAEKYGPGSVGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAVEEDDRMYGGSSR-S
RTASAYGGEKLSSHEYSGRGKGYERE------------------REAVERLQKVGPKPSS
LSMAHSRGRPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHVSAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDMGRHETRPH
PQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRVPSAYHHASDSKKGS-
RQAHSGPAAQ------QPKPEPQAQQQL-QGRQAAPGPQQSQPPPSRQIPSGAQQQ----
-------Q------QQQQQQQQGLGLQH----PQQAQSQARLQQQS--------------
QPTLRGPASAA-SQPAGKPQ-TGPTTAAGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPLAQPTPGPGPAGMKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------ESPREMR-GRG----QAEG
PRRTLQVDPHSQRARRSPSASPERGSTPTSPYSLPQIAPLPSSTLCPICKTTELTSAPSQ
PNFNACTQCHSKVCNQCGFNPNPHLTEVTNWGSVGCQKPRVVGGFAMHLVEL--------
------DLS------------------------------------KWK------------
------------------------------------------------------------
--------------------------------ERIYAP---------A-FPSHCPALCIP
NRMSCCINSLPGVCQSWNEQP-CVCKQ----STAP-NPAQPL-LCPHVVLL--GPWHPLS
-------ELKDGA-PR--HPPE----------------------AVGEKSA---GFDPHG
KQENGST-SWGSTALLFGRGESWHLPSPAVLLQHQVFASTKQHRDPNKGTGHLVHSEDSP
KIG--VSAQIHPVL--------PGSGL---------------------------------
-----GLEQAPAHASPCAHPRGAGALRSPAGPRAARGAAEGESCCVCSP-QTEPAPMQRH
---AAA-PRARCAFQL-AVHSLMPPNYNACTSCRQQVCNMCGFNP-PHLAEKNEWLCLNC
QTQRLLEGSLADPAPMPLP-APKQPVSGSPRHQPTAASQRALAPAEPVAPP---------
---------------------------E--RQP-SPARSLRAPEQSRAPS---------P
APEKKPLVQAEEKPLPKAAPEPSVPAPKGKSVSPKLEGESKEGRAAP---------ET--
-------------------------------------------------QKAKELEGQAP
APFPRDVLTAPQSLSDTGYSSDGISSSQSEITGLV-QQEEEKLSGTGLAGQSPPSPSELT
KLES-SMRPLLEARGA-PAETGK-GSE----AREEQRQRQRPRYLSITPEAFDSDEELED
ILEE-DEDSLEWENQREQRESVESSDEFGSKLRHDYVEDSSEGGFSPVPGHPKGRE-EVA
-DEEFMRRQILEMSAEEDNLEEEEE------EGYGRSKCSAPK------AEVEKGKEP--
-SSAKRRLPHGPGGLYKEERKELEAAESD--DISTTQGGLRRFKTIELNSTTGYGREMEV
SQEADAGLEREPELEMESLMGSPEERSRGEYSSTLPATTPSYTSGTSPTSISSLEEDSDS
SPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
P--SIDSEAESFD-AVTSKLYKSGSEYNLPTFMSLYSPTEKVES--VQPT--RPLKSAEE
AYEEMMRKAEMMQK-QQVQQAQQDISYGGSTYQQVGY-RSTEGQNGFQYQYADKYGYDSG
PTRPSQPDYSSSLSKPGAVYEEILQTSQSIARMHQSSSFDLALEKGDKKKGQEEAYQEKH
FLNAESAYAELMKQNGGPLTPGTSPTQLSAPVSFT-------S-EGNKAVPDVRVTQ-HF
AKEGQDL-AKLQSTPAAPSP-APKPITAPYTYSKGTS-MVTTAVASPTSTPRIYSSAE--
-------AVSTPARSYVPSKSTISYGSQTEDITRSKVGVETSVQMAREKLQGVSDGKPP-
--PAKTYSLFKSSSPPLSPTSPTQSPTRAAPRAAVSSGPTAKSTAEFSTQTQSPLLAYDV
PTTTGPSASSPMVAQGTQTPHQAGSPRLTRQQSSQDAPFMLITLAADAASQTKPPTS--S
GSPASSPTRISRQVITHGYGQEPEQPLGTFIRAQHV--K-DPAQKVPVT-----------
----SGPDGITGLYSWGALPAENISLCRISSIPGTSRVEPGPKVPSSSAVDLRTALKSAP
IIITDQGMDLTSLATEARKYCLTLDQIPSRQSTAIQPLIINLNAQEQPHAIIAASSTAGL
AIASPMLISQPKQPVVYGDPFQSRMDFGQGAGSPVCLAQVKQVEQGVQTGAGRASGAAGP
APTSKPEPPA-SPQAKFSRYNLPSQM---VKKDVLITQTSVAHSVSGLQQPFQQEQGSEL
YRAVPVELKTQSPLLALGGKKSQVMMVQVEDVTAGPVTKVLKEEPPANVLDLTGVKAESQ
VACCDVVYKFPFGSSCTGAFNPTSKVPEKKAADT--VPSRKASGPLYGSREQEVPETFPY
REQP--APALYEEHKFYPTGTFGRLYSSMSDTNLSEIGMNYYPLKGDQPFHE----AAVD
LSTMKHSYSIGFAEGGYLGQGLQYGSYSDLRQPADLLGHPLPMRRYSSASNIYSDYRYSP
RGDLASFQESSLAHYSATTAREISRMCAALNSMDHQYGARHA-----NGPDTLSYG-PGG
RGLP-----AQPGVPVAPKPSGMFNPSVPETRQGFSSLAQYNV-PGVRLGAVRQMFPSSA
TVRAADGMIYSTINTPIASTLPITTQPASVLRPMLR--GLYRPYGPTGMAAVPLASLARV
PVVAPRVPLAPQGLYRYPAPSRLPASS---MMETPVYLGKAVSAAPGTGPAAKAPPAPA-
------TGMQRAEASGAAPRTE----P------------------------PAVGSKEGG
QA-APVPKP--ASESVQREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERE
RAELQRHREKRP------------------------------------------------
------------------SSPPPG-AEPASRPPEGPT----EVPRGPMHNGHGWTPAGQA
LP----GGPETASGPR-YPAPQRPLSSSASDMSLQAEETWEPGRG--IKKRNSMPRLRDA
YEKET-------ARKTADSSVQTDEEDGEERYMLSR-RRRSRRSTDCSVQTDEEDSGEWE
QPVRRRRSRPSRHADASTEGKADG---T--------------ARGVASIGIQTISDCSVQ
TEPDQLLRVSPSIHITT-HDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIVVPQL
TVPTTITPYSTNLQMVSTGPLDPHAVRQQTLGKFEKKKPDPLEIGYQSHLPADSLSQL-V
TRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFT-DSAQRQQTLPRPI
KTMQRSLSDPKPISPTSEEAGKDRFSLYQHSLLPGTQVGTLQSSPLARKVKRTLPSPPPE
EPHVALGSPA-TQQLYLGSLAPKAPAAAP---VTKASLLKELDRDLKLVEHESTKL----
---------LDAKLKYLELGITQRKESLLKDR-GTRDHPYLRSLADRRDYLSDSELHSLR
LATYDSAGLRP----APAAQYPDFTAASYGA------YPY-----AAPPGPPTFPATRPQ
PP--QFPA-ASTT--QDGLPPAP----LPAFASPAAFPA-PG-----SAYPELSAPDQPG
FRPQN-PYQAQGTFAGTAGVPAAQPVLYQSPSD---AHQKPRQTSLAELEQKIPTNYEVI
SVATSSSAVPD--VTLGAAAVS--SSYEQYKAPEA-RLADRTSITQGPSTSFSSESLYTS
LEQNIPRNYVMIEDISELTKESPVV--DGQKAEPAGTG-ANGRHSKE-KSEMLDGEGPSR
PCCYSKAEDESEEDIYDHHGPDHRGKNSYHRES--NGRVSGSS---ASSSYYYGDSEYRH
SSRADKHGSGTALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSGRDLVDEEERVYSSSGRT-
-RSSTYGLEKSSGRDAGGRSKSF--E------------------REGAERSQKGGSKPSS
LGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSVV--PPQSAGDPCSQFCSS-HSLPD
VQEHI-KDVPRNHLYKHEEGYGMDDSHCVVSDS---EGQRHMNLHNTSRDITKTPC---R
RSMAKHDGDILVYLISWNRLNKPWAMKMHHGRKAPPTGEGTWGHVRSIT----------A
HGASQKLCAAQGNHRHNWSARLPLPSEIAKARPSSRKDTQLQQSTAQNDAASADALRSAP
ANP--ADQTSSPCPDECGLYHQASYVRQGRAQTPSEPVYTQPHKK------------PPS
APQSLGCNCYKRCNEAPPQDPPVLLHQVTA----SSAPA--SVLTTTPHCLAL----LTE
LM-QPGPEQSHK------QQH--SGRPRQ-----------EQAPNP------AR-SD---
--------------------RRGSPQHWETYP--ALARPGAPPAPVPCSIPGHVPRQ---
--VPLKSEQTDTAKPAAK--------------VPQQPGRAPA--AQ-PPGAADSKLGPRA
AGTRGPTGTAMGQPGAEGESVF-KILPGGAAEQAGKLTEAVSAF--GKKFTSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGL------GP--GPGAGKPPSALA----G
GGQLPVAGAA-------RAAGPPTPGLGPVPGPGP----G--------------------
--PGPGSVPRRLDPKEPLGSQRTTSPTPKQAS---ATAPGRESPRETR-AQGPSGQEAES
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERSPRGPG----AT-------------------------QSGPRQAE--------
---AARATSVPGP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPAGEAQGKSATTVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPSPSKGQPKIVFSDASK
EAGPRPPGSGPGPG------PTP--GAKTEPG----AR----------------------
------------MGPG----SGPGALAKTGGTASPKHG-----RAEHQA-ASKAAAKPKT
MPKERASACPLCQAEL-NMGSRGPANYNTCTACKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPL-PLPTPQQPPAGVPHRAAGAAPLKQKGPQGLGQPSGSLPAKASP
QATKASPQAT-------KASPQATKASPQTTKASPQAKPLRATEPSKTSS---------S
AQEKKTVTSAKAEPVPKPPPETTVPP---GT--PKAKSGVKRTDPATPVVK-PVP-EAP-
--------------------------------------------------KGGEAEEPVP
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SLRPSLEAQAVAPSAE-WSKPPRSS-SSAVEDQKRRPHSLSITPEAFDSDEELGD
ILEE--DDSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--DM
TDEEFMRRQILEMSAEEDNLEED-DTAV---SGRGLAKHSAQKASA--RPRPESSQE---
---PKRRLPHNATTGYEELLSEAGPAEPTD-SSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEDMMRKAEMLQ-RQQGQVAGARGPHGGP-SQPTGP----RSQGSFEYQDTQDHDYGGR
ASQPVAESTPAG--LGAAVYEEILQTSQSIARMRQASSRDLGFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPVSSTL-TSKEVGMTFSQGPGSP-ATTAS------PTRGYMTPTSP
AGSERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPPGSGRAPREKPLSGGDSEVGA
PQPSRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----PRATAEFSTQTPSLTLSSDI
PRSPGP--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPIMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--TSHSYSQTTPPSASQMPSEPAGP-PGFPRA----------------
--PSAGTDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVSGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVTPLARRDILITQMGTAQGVGLKPG-PVPEPGAEP
HRATPAELRSHA---PPGTRKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVTDT--ALPGQSSGPFYSPRDPEPPEPLTF
RTQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPLRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--SGGPDLVQY-QPQH
GPGL-----SAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQA-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAP-RFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPELPAGVAREEPFSTTAP-AVIKEAPVAPAPGPAP----APPPGQKPAG
EAV-AGSGSGVLSRPASEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQLQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHA
AFI-AVAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-DPSTVRRIADSSVQTDDEEGEGRYLVTR-RRRTRRSADCSVQTDDEDNADWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTT-------AAATARAMSSVGIQTISDCSVQ
TEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
IGPTAISPYLPGIQIVTPGAL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKQFIADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYTA-GSSGPTQNGFPAHQ----APTYTGPSTYPA-PTYPPGTGYPAEPGLPSQPA
FHPTG-------HYAAPTPMPTTQSAPFPVQADSRAAHQKPRQTSLADLEQKVPTNYEVI
GSPAVTMSSAPPETGYSGPAV-SG-SYEQGKAPEHPRGSDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTASESQRLEPLGPGGVSGRPGKD-PGEPAVLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP---------STHYYGDSDYRH
GARADKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGSSSR-S
RMASAYSGEKLSSHDYSSRGKGYERE------------------RDTAERLQKAGSKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYMLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHTVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDMGRHEARPH
PQASPAPAMQKK--------GQPGY--------PSSADYSQSSRAPSAYHHASESKKGS-
RQAHTGPSAL------QPKADTQAQPQM-QGRQAAPGPQQSQPPSSRQTPSGTASRQPQT
QQQQQ-----------QQQQQQGLGQQA----PQQAPSQARLQPQS--------------
QPTTRGTAPAA-SQPAGKPQ-PGPTTAPGPQP--------AGP-----------------
----PRAEQASSSKPPAA--------------KAPQQGRAPQAQTTPGPGPAGAKP---G
ARPGGTPGAPASQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------MGNEASLEGGAGDGPLPPG--G--------AGPSAGKPPSAPSGGGQL-
-PAAAATRAT-------AG------PPGPG--PGPGPGPR--------------------
--LGPDSISWRLDPKEPLGSQRTASPTPKQAS---ATALGHERPRETR-AQGPAGQEADG
PCRTLQVDSRMQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQEHS-WGPG----GP-------------------------QLGSRQAE--------
---TSRATSVLGP-AQAAAPLEVGKVSPQPSL-PTKPSTAEPRPPAGEAPAKSATTVPSG
LSASEQT-QEGLTGKLFGLGASLLTQASTLISV-QPEADPQGQPSPSKGPPKIVFSDASK
EAAPRPPSSGP--G------PAP--GTKTEPG----AR----------------------
------------MGLG----SGPGTLAKTVGMTSPKHG-----KAEHQA-APKTAAKPKT
IPKEKA-TCPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGR-------------------APHHAAVSAPLKQKGPQGLGQPSGPLPTKASP
LPTK--------------ASPLSPKSTPLPNKASPQAKPVKAPESSKTPS---------S
AQEKKTGVPAKAEPIPKPPPETTLPP---GT--PKVKSGVRRIDRATPVVK-AVP-EAS-
--------------------------------------------------KSGEAEESVG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SVWPLLEAQAVAPSAE-QSKPPCS---SAGEKQKRRPLSLSIMPEAFDSDEELED
ILEE-DEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSESGLSPLPPQPPLRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAA---SGRGLTKHSTQKGST--RPRPEPGQEP--
----ARRLPHNATTGYEELLSEGGPAESTD-SGGALQGGLRRFKTIELNSSDSYSHELDL
GQGPDAILDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTEIPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVVGAHGPHGVP-SQPTGP----GGQGIFEYQDAPDRDYG-R
GAQPAPESTAAS--LGTAVYEEILQTSQSIARMRQASSQDLAFPEDKK--------KERQ
FLNADSTYMDPMKQNGGPLTPGTSPTQLAAPMSFTTST--SSDSSGGRVIPDVHVTQ-HF
AKEPQNS-LKLHSSPATPSS-ASKEVGTSFSQGLGTP-ATTAVAP-------WYITSTSP
DGSERTLSPSSTAYSYGQSLTTANYGSQTEELPEASSGSAVGSRAAREKALRRTDGEAGP
PRASWGYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPIPSLEM
PRSPGTPTSTSMVAQGTQTPHRPSTPRLVWQQTSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--ITHSYSQTTPPSVSQLPSQPPGPPPGFPRV----------------
--PSAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRHPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGNATTVSI
TMASSVLMAQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRSGSRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTTQSVSLKSG-PVSEPSAEP
HRAIPAELQSHA---LPGARKPHAVVVQMGEGTAGTVTTLLPEE-SASALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVADT--ALPGQSSGPFYSPQDPEPSEPPTY
RAQGVMGPGPHEEQRSYPQGFPGRLYSSMSDTNLAEAGLNYHAHRVGQLFQGPARDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPIRRYSSVSNIYSDHRYGP
QGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GTGPDLVQY-QPQH
EPGL-----SAPQGLAPLRPGLLGNPTFPESHPGPRNLAQYGPAPGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGPTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPIPNRFPISSSVPPAEGPVYLGKPA-AKAPGVGGYP-------
----------RPELQAGAAREEPYSTAAPA-AVKESVAAPTP------PPALPSGQKPPG
DAAAAGGGSVTLGRPGLEKED----------------LERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQ----QQLEEQKQRQKAPFPATC-DAPGRGPPPA--------APELAQNGQYWPPLTHT
AFL-AVAGPEGSGQSR-EPVLHRGLPSSASDLSLQTEEPWEAGRS-SLKKQHSMPRLRDA
CEPESAP-EPYVVKRIADSSVQTDDEDGEARYLLTR-RRRTRRSTDCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------TTTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKVHVSPQKHFTTDSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EGHLPLAGQA-PPQLYAASLLQRGLAGLTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
EELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRECSPLHGLGVHRDYLSDSELNQLR
LQGC----I------TPARQYAGFPATA----V-AP---------ATPSVPTAFQQPRFL
PPAPQYTV-GNIGPAQNELPAHQ----APTYPGPNTYPA-PAFPPSTSYSAEPSLPNQQA
FCPSG-------HYASQTPMPTTQSTLLPVPADSHAPHQKPRQTSLADLEQKVPTNYEVI
PSPVVAMSSAPSETSYSGPVV-SS-SYEQGKAPELPQASDCGSVSQSPVPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTVPDSQRLESLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEE-SEEDSYDSRGKAGH----HHRTMESNGRP--------ASTHYYSDSGYKH
GARVEKYGPGPVGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--TAVISSPASRGRKFQDEITYGLKKNVYEQQRYYGVSTRDIAEEDDRMYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------REAVDRLQKAGPKPSS
LSMVHGRARPPMRSQASEEESPVSPLGRPR----PTGGT-LPP-GDTCSQFCSS-HSMPD
VQEHV-KEGPRAHSYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHGPAKEHRH
HSEHGRHT-----GRHAGE-------------------EPGRRTAKSHARDLGRYEARPH
PQPSLTPAMLKK--------GQPGY--------PGPTDYSQPCRGPVAYHHASDSKKGS-
RQAHSGPAAL------QPKPEPQAPPQL-QGRQAAPGPQQSQPPTSRQMPSGAALRQPQM
QQ---------------QQQQPGLGQHP----PQQASSQARPQ-QS--------------
QPTARGPASSA-SQLAGKPH-PGSTTAPGPQP--------AGS-----------------
----PRAEQADGSK-VAA--------------KTPQQGRASQAQPTPGPGPAGTKP---G
ARPGGTPGATPGQPGADGESVLSKILTGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-------------------NT-I-EV-------ATFLRRLA-------QPGE-------G
WGPQPIHIPLQADS--LRC---------------ISNSHF--------------------
--QCHFSTSRRLDPKEPLGSQRAASPTPKQAS---ATTPGQESPQETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSRQGE--------
---MARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGTLPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGNKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
LPTKAS--------------PLS-------TKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTADRDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPIGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPGTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAVREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESAA-EPCMVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGSAV-SS-GYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSPAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPISPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
QQQQ-----------QQQQQQQGLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

--------------PTSRLLNLF--------------------------GKLMAS----D
GGS-KLRII--------P----------CQ--SDPGPGQP--------------------
--PPQAGTSRRLDPKEPLGSQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPQ
GKPEQERP-RGPG----GP-------------------------QPGSCQAE--------
---TARATSVPGS-AQAAAPPEVGRVSPQPPQ-PTKPSTVEPRPPAGEAPAKSATAVPTG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFSDASK
EAGPKPLGSVPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALAKTGGTTSPKHG-----KAEHQVASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPPPLPTSQ-QPPVGAPHRASGTSPLKQKGPQGLAQPSGPLPAKASP
LPTK---------------------ASPLPTKASPQAKPLRASEPSKTPS---------S
ALEKKTGAPTKAEPMPKPPPETTPTP---GA--PKVKSGVRRAEPATPVIK-AIP-EAP-
--------------------------------------------------KGGEVEDLVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPCPPSPSEIH
KVGS-SMRPLLEAQGLAPSGE-RSKPPCS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-EEGSVEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGHGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGTAEATD-GSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAPGARGPHGGP-SQPTGP----RGPGSFEYQDTADRDYG-R
AAQPATEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSLDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEAGMPLSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTGHSYGHSPTTANYGSQTEDLPQVPSGLAAAGWAAREKPLSASDSEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSLGKL--G----QRATAEFSTQTPSLAPASDR
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHANAS
TSPLCSPTETQP--TTHSYSQTTPPSVSQLPPEPPGL-PGFPRA----------------
--PSAGVDGHLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKLARYNLPNQVAPLARRDVLITQIGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGVRKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSAPEKSMADA--APPGQSSGPFYGPQDPEPPEPLTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDTVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QSQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGHG-TAIRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPVASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEMPAGAAREEPLPTTTPA-AIKE-AGAPAP--------APLAGQKPPA
DA-APGGGTGALSRPGLEKEEVSQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWETSRS-GIKKRHSMPRLRDA
CEPESAP-EPCMVRRIADSSVQTDDEDGEGRYLLTR-RRRARRSTDCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSST--------AAATARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAQLPPESLSQL-M
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-TPQLYAASLLQRGLTGPTAVPTTKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPSGQYVDFSATAA---A--P---------TTPSGPTAFQQPRFQ
PLAPQYTA-GSGGPAQNGFPAHQ----APSYPGPSTYPAAPAFPPGTSYPAEPGLPNQQA
FRPTG-------HYVGQTPMQTTQSTLFPVPADSRAPPQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETGYSGPTV-SS-GYEQGKVPELPRAGDRGSVSHSPAPTYPSDSHYTN
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRSKGGH-----HRSMESNGRP--------TSTHYYGDSDYRH
GARTEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSSLVSRSRKFQDEITYGLKKNVYEQQRYYGMSSRDAVEEDDRIYGGSSR-P
RAPSTYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPSRHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----GRHTGE-------------------EPGRRAAKPHTRDLGRHEARPH
SQPSSAPAMPKK--------SQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAP------QSKAEPQAQPQL-QCRQAAPGPQQSQPPSSRQIPSGAMQQQ--Q
QQQQ---------------QQQGLGLQP----PQQAPTQARLQQQS--------------
QPTTRGSAPVA-SQPAGKPQ-PGPTTATGPQP--------AGL-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQSTPGPGPAGVKA---G
ARPGGTPGAPASQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------ADKQLDCQVSPTATVLVR----------AHASGPGAGSPCRTDF----A
-----------------------------GPQKALFAYDF--------------------
--QCHFSVSRRLDPKEPPGSQRAASPTPKQAS---ATAPGRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAQSPAKQPL
GKPEQERS-QGPG----AP-------------------------QPGLRQAE--------
---TSRATSVPGS-AQAAAPPEVGRASPQPPL-PIKPSTADPRPPAGEALAKSATTVPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQVAPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PAP--GAKTEPG----AR----------------------
------------PGPG----SGPGALARTGGTTSPKHG-----RVEHQA-ATKATAKPKT
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-PLPTSQQPPSGAPLRAAGAAPLKQKGPQGLGQPSGPLPAKASP
----------------------------LPTKASPQAKPLKASEPSRTLS---------S
AQEKKTGIPAKAEPGPKPPPETTLPP---GT--PKAKTGTRRTEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEELAG
KTYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SLRPSLEAQGPAPRGE-QSKPPR----SSGEEQKRRPHSLSIMPEAYDSDEELED
ILEE-EEDSLEWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DVAP---SGHGLAKHGTQKGGP--RPRPEPSQDPA-
-VLPKRRLPHNATTGYEELLSEGGPAEASD-GTGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLEREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPTRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSSRPLKSAEE
AYEEMMRKAELLQ-RQQGQVAG------GP-SQPTGT----RSQGAFEYQDTPDQDYG-R
AAQPAPEGTPAS--LGTAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEVGISFSQGPGTP-ATTAVAPCPASLSRGYMTPTSP
AGSERSPSPSAVGHSYGQSPATANYGSQTEEIPQALSGATASGRAARDKPLSVSDGESGP
HKASRGYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPASDM
PRSPGAPTPTPMVAQGTQTPHRPSTPRLVWQQPSQEAPFMVITLASDASSQTRMVHASAS
TSPVCSPTDTQP--TTHSYSQTTPPSMSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLAVYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPRETKFARYNLPNQVAPLARRDVLITQMGSAQSVGLKSG-PVAEPGAEP
HRAAPAELRSHA---APGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
MACCDMVYKFPFGSSCTGTFHPTPSAPEKSVSDV--ALPGQSSGPFYSPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLHGRLYSSMSDTNLAEASLNYHAHRIGQLFQGPGRDSAVD
LSSLKHSYSLGFVDGRYLGQGLQYGSYTDLRHPTDVLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG-G-GGPDLMQY-QPQP
GPGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPGNLAQYRPTVGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRR-GMYRPYVSGGVTAVPLTSLTRM
PVIAPRIPLGPTGLYRYPAPSRFPAASSIPPAEGPVYLGKPAAAKAPGAGGPP-------
----------RPELPTGAAREEPLSTATPA-AAKEAVAAPP--P----APAPLASQKPQV
DAA-PGGGSGALSRPGLEKEEAAQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKTPFPVAC-EAPGRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AVAGPEGPGQPR-EPGLHRGLPSSASDMSLQTEEPWEAGRS-GLKKRHSMPRLRDA
CEPESGP-EPCAVRRIADSSVQTDEEDGEGRYLLSR-RRRVRRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAAASSSPA--------TAAARATSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-AQGVVGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAQLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESTKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQHGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGHDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYADFPVTA----A-AP---------ATPSGPTAFQQPRFP
PPAPQYTA-GSGGPTQNGFPAHQ----PPTYPGPGTYPA-PAFPPGTSYPAEPSLPSQQA
FRPTG-------HYTAQTPMPTTQSTLFPVPADSRAPHQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPPETSYSGPAV-SS-SYDQGKAAELPRAGDRSGVSLSSASTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSISTTPDSQRLEPLGPS-SSGRPGKE-PGEPSILEGTAL
PCCYTRGEEESEEDSYDPRGKSGH-----HRNLESNGRP--------ASAHYYSDSDYRH
GTRAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPVEEDDRMYGGSGR-S
RVASAYSGEKLSGHDFSSRGKGYERE------------------REAMERLQKAGPKPSS
LSMAHGRSRPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPSRHTSAKEHRH
HSDHGRHS-----GRHTGE-------------------EPGRRAAKPHTRDLGRHEARPH
PQPSPAPAMQKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPTAP------QPKPEP--QLQS-QGRQAAPGPQQSQPPPSRQTPSATASRQPQT
QQQQ-------------QQQ-QQQQLQP----PQQAPAQARLQQQG--------------
QQATRGPASAA-SQPAGKAQ-PGPPTVTGSQP--------AGP-----------------
----PRAEQANGSK-GTA--------------KAPQQGRPPQAQPPPGPGPAGMKA---G
ARPGGTPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------TSRRLDPKEPLGSQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQDADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPQ
GKPEQERS-QGPG----GP-------------------------QPGFCQAE--------
---IARATSVPGS-AQAAAPPEVGRVSPQAPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAETQGQPAPSKGTPKIVFSDASK
EAGPKPSGSVPGPG------PAP--GAKTEPG----AR----------------------
------------I---GPGS-GPGALAKTGGTTSPKHG-----KAEHQVASKAAA-KPKT
MPKERA-TCPLCQAEL-NMGSKSPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLAQPSGPPPAKSSP
LPTK---------------------ASPLPTKASPQAKPLRASDPSKTPS---------S
ALEKKTGVPTKAEPMPKPPPETTPTP---GA--PKVKSGVRRAEPATPVIK-TIP-EAP-
--------------------------------------------------KGGEVEDLVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPCPPSPSEIH
KVGS-SMRPLLEAQDLAPSGE-RSKPPCS---STGEEQKQRPHSLSITPEAFDSDEEMED
ILEE-DEGSVEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGHGLAKHGTQKGSP--RTRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTAPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAPGARGPHGSP-SQPTGP----RGPGSFEYQDTADRDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSLDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEAGMPLSQGPGTP-ATTAVAPGPAGLPRGYMTPASP
AGSERSPSPSSTGHSYGHSPTTANYGSQTEDLPQVPSGLAAAGWAVREKPLSASDSEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKL--G----QRATAEFSTQTPSLAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TAHSYSQTTPPSVSQLPPEPPGL-PGFPRA----------------
--PSGGVDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSAVCLTQVKQVEQAVQTAPYRSGPRG--
----------RPREAKLARYNLPNQVAPLARRDVLITQMGTAQSVGLKPG-PVPEPGAEP
HRVSPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSAPEKSMADA--APPGQSSGPFFGPRDPEPPEPLTY
RAQGLVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAFGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QSQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGHG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPLYLGKPAAAKASGAGGPP-------
----------RPEMPAGAAREEPLPTTTPA-AIKEAAGAQAP--------APLAGQKPPA
DA-APGGGTGALSRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWETSRS-GIKKRHSMPRLRDA
CEPESAP-EPCVVRRIADSSVQTDDEDGEGRYLLTR-RRRARRSTDCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSST--------AAATARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-M
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-TPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPSGQYVDFPATAA---A--P---------TTPSGPTAFQQPRFQ
PLAPQYTA-GSGGPAQNGFPAHQ----APSYPGPSTYPAAPAFPPGTSYPAEPGLPNQQA
FRPTG-------HYVGQTPMPTTQSTLFPVPADSRAPPQKPRQTSLADLEQKVPTNYEVI
ASPIVAMSSAPSETSYSGPTV-SS-GYEQGKVPELPRAGDRGSVSQSPAPTFPSDSHYTN
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----HRSLESNGRP--------ASTHYYGDSDYRH
GARTEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRSRKFQDEITYGLKKNVYEQQRYYGVSSRDAVEEDDRIYGGSSR-P
RAPSTYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPSRHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAP------QSKAEPQAQPQL-QGRQAAPGPQQSQPPSSRQIPSGA-------
---------------------------P----PQQAPTQARLQQQS--------------
QPTTRGSAPVA-SQPAGKPQ-PGPTTATGPQP--------AGL-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG-PLPPGGSGL------GPGPGPGAGKPPSAPA----G
GGQLPAAGAA-------RAAAGPPA---SGPGPGPGPGPG--------------------
--AGPGSVSRRVDPKEPLSSQRAASSTLKQAS---ATAPGRESPRETR-VQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHSKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LYSP---------ALSPAHSPAKQPL
GKPEPERS-RGSG----GP-------------------------QPSPRQAE--------
---TARATSVPGP-AQATGPPEVGRVSPQPPL-PTKPSTAEPRPPSGEASGKSATTVTSG
LGAGEQT-QEGLTGKILGLGASILTQASTLMSV-QPEAEPQSQPSPSKGPPKIVFSDASK
EIGPRPPGSGP--G------QAP--GAKTEPG----VK----------------------
------------TGPG----SGPGAMAKPGGA-SPKPG-----KAEHPV-ASKAAAKPKT
TLKERV-LCPLCQAEL-NVGGKDPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGGLGEPTPL-PLPTPQQPPTGTPPRAAGTAPLKQKGPPTVAQPSGPLTAKTSP
LPTKASPQ---------------------PTKASVQAKPPRASEPSKTSS---------S
AQEKKTGVPAKAEPVPKPPPEPTMPP---GT--PKGKSGVRRTEPVSTVIK-AGL-EAP-
--------------------------------------------------KGGEAEEPVS
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVSGPRPPSPSELH
KVES-SMRPLLEAKAVAPSGK-PSKPPSG---STVEEQKRRPHSLSIMPEAFDSDEELGD
ILEE-EEDSLEWGHQRDQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-TEL
TDEEFMRRQILEMSAEEDNLEEEEDTAI---SRPGLAKHGTQKGSS--RPRPEPSQEPAA
AAPPKRRLPHNATTGYEELLSEGDPAEATD-G--TLQGGLRRFKTIELNSTGSYGHELDL
GQGPDASLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPSRLYKSGSEYNLPTFMSLYSPTEMPSGSAATPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQLSAARGPHGGP-PQSTGP----RGPGSFEYQDTPDRDYG-R
ATPSASEGTAAN--LGATVYEEILQTSQSITRMRQASSRDLAFAEDKK--------KEKQ
FLNADSAYLDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDTTGGRVIPDVRVTQ-HF
AKEPQDP-LKLYSSPASPSL-ASKEVGMS-SQGPGTP-ATTAVAPCPPTLPRGFVTPPTP
ADLDHSASPSSTAHSYGQTPTTANYGSQTEELSQAPSGPVLGGWATREKPASGIDGEVGT
HQPSRAYSYFAGSSPPLSPSSPSDSPTFSPGKL--G-----RATAEFSTQTPSPTPASDM
PRSPGAPTSSPMVPQGTQTPHRPSTPRLVWQQSSQEAPIMVITLASDASSQTKMVHASAS
TSPLCSPTDTQP--TSHSYSQTTPPTGSQLPPEPPGP-PGFPRA----------------
--PSTGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGHRLPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTTVQPLVINLNAQEQTHTFLGTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVSLKPG-SVPEPGAEP
HRATPAELRPHA---LPGARKPHTMVVQMGEGTAGTVTTLLPEE-PVSALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHHPPSAPEKSVADA--APPGQSSGPFYTPRDPEPDEHPSY
RA--------REEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRIGQLFPGHGRESAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGPG--SGGPDLVQY-QPQH
GPGP-----SAPQGLAPLRPGLLSNPTFPEGHPSPGSLAQYAPTAGQG-AAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRS-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPIASGVPPAEGPVYLGKPAAAKAPVTGSAS-------
----------RPELPAGAAREEPLSTPAST-STKEAPVAPTP--------APPAGQKPPA
VDA---AVAGASSRPGLEKEEGSQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPPAC-EAPSRGPPPA--------ATELAQNGQYWPPLTHA
AFI-AVAGTEGPGQPR-EPMPHRGLPSSASDMSLQTEEPWEASRS-GIKKRHSMPRLRDV
CEPESGP-EPSTVKRIADSSVQTDDEDGEGRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRKSRLSRHSDSSADSKHEATASSSTA--------ATAARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIRITAATDPKVEIVRYISAPEKTGRGESLACQTEPDAQ-AQGLAGTQL
VGPTAISPYLPGIQIITPGAL----------GRFEKKKPDPLEIGYQTHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTTDSALRQQTLPRPM
KILQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGGQVSALPPNGLARKVKRTLPSPPPE
EAHLPLAGQA-PPPLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLSEHRDYLSDSELNQLR
LQGC----P------TPTGQYVDFAATV----A-AP---------VTPSGPAAFQQSRFP
PPTPQYTAPGGSRPAQNGFPAHQ----TPTYSGTSPYPA-PAFPPGTGYSAEPSLPTQQA
FRPTG-------HYATPTPMPTTQSPGFPVAT-----AAKPRQTSLADLEQKAPTNYEVT
---MVTMSSASSEMGYGVPAV-SSSGYEQSKAAELPR----ASVSQSPAPTYPSDSHYTN
LEQNVPRNYVMIDDISELTKDSTPTGPDSQRLEPLGPGGAG-RPGKEPGGEPSVLEGPTL
PCCYGRGEEESEEDSYDPRGKVAH-----HRSMESNGRS--------TSTHYYGDSDYRP
GARAEKYGPGSVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YLS--PAVSSSLASRGRKFQEEITYGLKKNVYEQQRYYGASSRDAAEEDDRMYSGSSR-S
QMASAYSGEKLSSHDFRGRSKGYERE------------------RETAERLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRSHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SERFRHHGGHPVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDLGRHEVRPH
PQPSSAPAMPKK--------GQPGY--------PSSAEYSQSSRAPSTYHHASDSKKGS-
RQAHAGPAAP------QPKPEPQAQPQL-QGRQPAPGSQQSQLPPSRQMPSGAASRQLQQ
QQQ----------------QQQALGQPPP---SQQAPPQARSQQQS--------------
QPTTRASAPAA-SQPIGKPQQPGPTATPGPQP--------AGPVSNVWEGP------TLG
SMLQPRAEQANGLK-GTA--------------KGAQQGRAPQAQPTPGPGAAG-------
ARPGGTPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------------------------KREVATFLR-------RLAHPGE-------G
WGPQPIHIPLQADS--LRC---------------ISNSHF--------------------
--QCHFSTSRRLDPKEPLGSQRAASPALKQAS---ATTPGQESPRETG-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSRQGE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKLLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKVAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
LPTKA---------------------SPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKSGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVKRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPART-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGS-SQPTGP----RDLGSFEYQDTADRDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGVRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLLRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPVSDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLHNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMSPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLSYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAAREEPLPTATPA-AIKEAAGAPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESGA-EPCVVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPDSLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPTGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPTDSRAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETIYSGSAV-SS-GYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------AGTHYYADSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEDGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQSQL-QGRQAAPGPQQSQSPSSRQMPSGAPQ-----
------QQ-------QQQQQQQGLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTAAGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MILPPQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAQSPAKQPL
GKPEQERS-QGPG----GP-------------------------QPGPRQAE--------
---TARATSVPGP-AQAAAPSEVGRASPQPSL-PIKPSTVEPRPPAGEGLAKSATTVPPG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQAAPSKGPPKIVFSDASK
EAGPRPPGSGP--G------PLP--GAKTEPG----AR----------------------
------------TGPG----PGPGALARTGGTTSPKHG-----RTEHQA-ATRATAKPKT
MPKEKA-TCPLCQAEL-NVGGKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-PLPTSQQPPTGAPLRVAGTAPLKQKGPQGLGQPSGPLPAKASP
----------------------------LPAKASPQAKPLKAAEPSRAVS---------S
AQEKKTGIPAKPEPGPKPPPETTLPP---GT--PKGKTGARRTEPATPVVK-SVP-EAP-
--------------------------------------------------KGGESEELAG
KSYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQGPAPRGE-QSKPPR----SSGEELKRRPHSLSIMPEAYDSDEELED
ILEE-EEDSVEWGHQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DATT---SGPSLAKHGTQKGGP--RPRPEPSQDPA-
-APPKRRLPHNATTGYEELLSEGGPDEASD-GTGALQGGLRRFKTIELNSTGSYGHELDM
GQGPDTSLEREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPTRLYKSGSEYNLPTFMSLYSPTETPSGSSATPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQGAG------GP-SQPTGP----RSQGTIEYQDTPDQDYG-R
PAQPVSEGTPAS--LGAAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLNADTVYMDPMKQNGGPLTPGTSPTQLAAPVSFSTSS--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPVSPSS-ASKEVGISFSQGPGAP-ATTAVAPCLASLSRGYMTPTSP
AGSECSPSPSSVGYSYGQSPATANYGSQTEELPQALSGPPVSGRAARDKPLSVSDGESGP
HMASRGYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTSASEV
PRSPGAPSPAPMVAQGTQTPHRPGTPRLVWQQSSQEAPFMVITLASDASSQTRMVHASAS
TSPVCSPTDIQP--TTHSYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSASADGPLAVYGWGTLPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTSTTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGLKSG-PAPEPGAEP
HRAAPTELRSHA---MPGARKPHTVVVQMGEGTAGTVTTLLPEE-PSGALDLTGMRPESQ
MACCDMVYKFPFGSSCTGTFHPTPNAPEKSVADI--APPGQSGGPFYSPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLHGRLYSSMSDTNLAEAGLNYHAHKMGQLFQGPGRDSAMD
LSSLKHSYSLGFVDGRYLGQGLQYGSYTDLRHPTDILTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG-G-GGPDLMQY-QPQP
GSGL-----SAPQGVAPLRPGLLGNPTFPEGHPSSGNLAQYRPTGGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRR-GIYRPYVSAGVTAVPLTSLTRM
PVIAPRIPLGPTGLYRYPAPSRFPTASSVPPAEGPLYLGKPAAAKAPGAGGPL-------
----------RPELPAGAAREEPLSTATPA-AAKEAVAA----------PAPLAGQKPPI
DTA-SGGGSGALGRPGLEKEDATQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPGRGPPPA--------ATELAQNGQYWPPLSHT
AFI-AVAGPEGPGQPR-EPGLHRGLPSSASDMSLQTEEPWEASRS-SIKKRHSMPRLRDA
CEPESGP-EPCSVRRIADSSVQTDDEEGEGRYLLTR-RRRVRRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAAASSSPAAA------AAAVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAVTDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-AQGVAGPQL
MGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAQLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVWAQG---LVQGGAGVSF-----
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
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-------------------------------------

------------------------------------------------------------
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------STLRRPEQLEQAAGQRSPSP---SLA---QSAPSSQSPREMR-GRGQPGPAAEG
PRRTLQVDARSQGSGRSPSVSPDRSSTPTSPYSVPQIAPLPSSTLCPICKTTELTSSPGQ
PNFNACTQCHSKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLHSP---------SPSPSQSPAKHPQ
PPAADKTPPAPRPLPQEQP-------------------------KPQPAAPQREPHGQGQ
PKPQEAARSSPQH-QPRSSPQHQPRSSPQH-Q-QAKPSPSEQRKTLGDAGAKPA-APAPG
AGAPEQP-QEGLTGKLFGFGASLLTQASTLMSA-QPEAPAPSQPSPGKVPPKIVFSDASK
EAGPRAPGAQGRAG------AAP--AAKP-------------------------------
-------------------------------------G-----------K-PEQGVKPKE
VPKARV-SCPLCKAEI-NVGSSEPPNYNTCTTCRQQVCNMCGFNPTPHLVEKNEWLCLNC
QTQRLLEGSLGDPAPMPLP-TAKPAPSGSPRHQPPGPGQQQRAPAPAEPAAPPE-QQP--
-------------------PPPPPPPPPPPPPPPSPARSLRAAEQSRTPSPAPAEKKPPA
PAEKKPPVPAEEKPLPKAALEPSRAP---ESVAAKGKSVTPKAEAEGKESQ-ALP-EAP-
---------------------------------------------------RAKEQEDSS
KPYPPDLSRSPQSLSDTGYSSDGISSSQSEITGLV-QQEEEKLSSTGLAGQSPPSPSELT
KLES-SMRPLLEGRGAPTESPERSKSRTE--PQEDQRQQQRPRYLSITPEAFDSDEELED
ILEE-DE---EWDNQRERRESAESSDEFGSKLRHDYVEDSSEGGFSPVPPRSKGQE-AEV
TDEEFMRRQILEMSAEEDNLEEDEE-GY---GR---TKYSVTKAGQ--KTEAEKGKEP--
-APAKRRLPHGASSMYTEDSKEVEAVEGDD--LSTAQGGLRRFKTIELNSTTGYGREMEI
GQEPDTSVDREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSISSLEEDSDS
SPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEEMREEEELLREQEKMREVEQ-QRI
RSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
P--SIDSEAESFD-AVASKLYKSGSEYNLPTFMSLYSPTEKVESGASQP-TSKPLKSAEE
AYEEMMRKAEMMQK-QQVQQAQPAFSSGST-YQQVGYHSTE-DQNGFDYQYGEEYRYDGG
LVHPSQPDYPSALPKAGAVYEEILQTSQSISRMHQSSSFDLAFKQGEKVKGQEGAYQEKR
FLNAESAYADLLKQNGGPLTPGTSPTQLSAPVSFA-----SSDSSTGKTIPDVRVTQ-HF
AKEGQDL-AKLQSAAAAPSP-VSKATTTPYAYSKGTS-TVTTAAGSPGIVLQSYSSSSPE
TPSIAGR-------SYTPSKSTVSYGSQTEDTTRTRT-VEISVQTAREKIPAVSDS---K
PSVPKTYTFFKSSSPPLSPTSPTQSPTRT-----------TKATAEFSTQTQSPVLSYEG
PAAAGPDTSSPMVAQGTQTPHQAGSPRLTRQASSQDSPFMVITLAADAASQTKPVSSGGL
TSPTSSPTRPSRQLLAHGYTQTPEPE--------QPT-GAYIRA-----QPVKDHAQK-A
PAVTSAADGITGLYSWGALPAENISLCRISSIPGTSRVEPGPKVPTSNAVDLRTALKSAP
IIITDQGMDLTSLATEARKYCLTLDHIPSRQSTAIQPLIINLNAQEQPHAIIAAASTASL
AIASPMILSQSKQPVVYGDPFQSRVDFGQGAGSPVCLAQVKQVEQGVQTATVRAGGVA--
--SGKPEPTA-APQTKFARYGMPGQMA---KKDVLLTQTGGAQNASGLPQSFPPEPGSEV
YRAVPVELKSQSPLLAMGGKKSQVMMVHMEEAATGPVTKVLKEEVPANVLDLTGMKPESQ
VACCDMVYKFPFGGSCTGAFNPTSKMPEKKSGETAAVPGRKAGGPMYGSREPELPDTFPY
REQPAPAPALYEEQKFYPASAFGRLYSSMSDTNLSEIGMGYYHTKGDQPFPGPAGDAAVD
LSTMKHSYSVGFAEGGYLGQGLQYGSFSDLRQPGEMLSHPFPMRRYSSASNIYSDYRFSH
RGDLASFQESSLAHYSATTAREISRMCAALNSMD-QYGGRHA-----NGPDVLPYG-PST
GQGATGGLAAQQQGPVPPKPSGMYNPTFPEGRQGFSNLAQYNVPGVRL-GTIRQMLPSTA
TVRAADGMIYSTINTPIASTLPITTQPASVLRPMLR--GLYRPYGPGGVAAVPLASLARL
PVVTPRVPLAAQGLYRFPAPSRPAP--AASMMETPVYLGKPVTSTAPAAVGAA-PA----
-AKAPAVPAAPPAPATGLQRAEPPPAAPRAEAP----AAPAAPKESGPVP--------PA
PK-PP------LDGA-QREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERE
RAELQRHREKRPSSPLPWSPPP--------------------------------------
----------AHP-RGPLRCHGCC-HTMGRHGPRR-AEGPAEAPRVLPHNGQAWPPPGQT
P-------PEGPAGPR-YPMPQRPLSSSASDMSLQVEESWEPSR--GIKKRNSMPRLRDA
YEKE-----TFAARKMADSSVQTDEEDGEERFMLSR-RRRTRRSADCSVQTDEEDSGEWE
QPVRRRRSRASRHAEASTEGKADGA------------------ARTASVGIQTISDCSVQ
TEPDQLLRVSPSIHITT-HDPRVEIVKYISAPEKTQRGESLACQTEPEPAPQPGVVVPQL
TVPTTIPPYSTNLQIVSTGPLDPHTVRQQTLGKFEKKKPDPLEIGYQSHLPAESLSQL-V
TRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFTTDLAQRQQTLPRPI
KTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPSSQVGGLQSSSLARKVKRTLPSPPPE
EPHVPLASPA-ASQLYLSSL-----APKATAPVTKASLLKELDRDLRLVEHEATKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLLKDRVGGRDHPYLRYPGDRRDYLSDSELHSLR
LAAYDSAGL------RPAGQYPDYTAAAA---ASYGAYPY-----PAPQGPAAFPPPRLQ
HP--QYP---TASTSQDGLPAAP----LPTFTSPGGFSAPGTAYPELGTPAQPGFQPQNP
YQTPS-------AFAGAATVPAAQPALYQSPADIAGGHQKPRQTSLADLEQKIPTNYEVI
GAATSS--SAVPDVTFSTA--PASSGYEQYKAPET-RPAERTSTAPGPSASYSSESLYTS
LEQNIPRNYVMIEDISELTKESP--AVDGQKAEPVGTSTDSR-HSRE-KSDLGDTESSSR
PCCYTKAEEESEEDIYDHHGPDHRGKNSYYRGTESNGRVSGSS---ISSSYYYGDSEYRH
SSRMDKHSSGTPLPKHSSKNLAPAVISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YSTTTSIGSSNVASRAKKMQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSSR-T
R-SSGYGVEKSSSREMGGRSKSYERE--------------------SMERSQKVSSKPSS
LSMSQSRGRAPMRSQPSEEESPVSPMGKSMGGSRTAGGPGPQSVGDPCSQFCSS-HSLPD
VQKHI-KDVPRSHSYKHEEGYGMDDAHCVVSDSEVSEAYHLGQEE---TDWFDKPR-EAR
AERVRHYSGHS------SSQKRPPVKHTYHDYD-EPPDEDPWQHDDYPQ-----HREHRH
HREYDRHS---GSSRHTSD-------------------EPPRRSSKQHPRESGRHEPRGH
GPSAGPK---KA--------QQPESR---APYGPSSADYAPSSR-PAAHHHGAETPKAQK
PSQPHGSATP------APKPEPLAHPQQAAARQQQAGQ-----PAARQQPAARQAAQPAS
----------------------------------------------------------SA
QPETRGRTPGPASS-RPPQQQPGPAQAAGKAPTTLHAQPGGHPAPAAWATP------GRC
STGRTKAEPTDTSKPAAK--------------VPQQPGRAPSAQPLGAAA--DSKAGPRA
AGPRGPAGMATGQPGGEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFTSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SVSRRLDPKEPPGSQRAASPTPKQAS---ATAPGRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHSKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAQSPAKQPL
GKPEQERS-QGPG----GP-------------------------QPGPRQAE--------
---TARATSVPGP-AQAAAPPEVGRASPQPPL-PVKPSTAEPRPPAGEALAKSATTVPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQAAPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PAP--GAKTEPG----AR----------------------
------------TGPG----PGPAAQARTGGTTSPKHG-----RAEHQA-ATKATAKPKT
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGELTPL-PLPASQQPPAGAPLRATGAAPPKQKGPQGPGQPSGPPPAKASP
----------------------------LSTKASPQAKPVRASEPGKTLS---------S
AQEKKTGILAKAEPGPKPPPETTVPP---GT--PKGKTVPRRTEPATPVVK-AVP-EAP-
--------------------------------------------------KAGESEELAG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMQPSLEAQGPAPRAE-PSKPPR----SSGGEQKRRPHSLSIMPEAYDSDEELEE
ILEEEEEDSLEWGPQREQPDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEEE-DTAP---SGRGPAKHAAQKGGP--RPRPEPSQDQG-
-APPKRRLPHNATTGYEELLSEEGPAEAGD-GTAALQGGLRRFKTIELNSTGSYAHELDL
GQGPDPGLEREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPTRLYKSGSEYNLPTFMSLYSPTEAPAGSSAPPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQVAG------GP-SQPGGP----RSQGTFEYQDTPDQDYG-R
AAQPASEGPAAS--LGAAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFSGST--SSDSGGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEVGVSFSQGPGAP-ATSAMAPCPAGLPRGYMTPTSP
AGSEHSPSPSSVGHSYGQSPATANYGSQTEELPQALSGPTISGRAVRDKSLSVSDGEGGP
HKASRGYSYFTGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPASDM
PRTPGAPSPAPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASAS
TSPVCSPTDTQP--TAHSYSQMTPPSASQQPPEPPGP-PGFPRA----------------
--PSAGTEGPLAVYGWGALPAENISLCRISSVPGTSRVEPGPRPLGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLSTSTTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDLLITQMGTAQSVGLKSG-PMPEPGTDP
HRAAPAELRSHA---LPGARKPHTVVVQMGEGAAGTVTTLLPEE-PAGALDLTGMRPESQ
MACCDMVYKFPFGSSCTGTFHPTPSAPEKSVADI--APPGQSGGPFYSPRDPEPPEPHTY
RAQGVAGPGPPEEQRPYPQGLHGRLYSSMSDTNLAEAGLNYHAHRMGQLFPGPGRDSAVD
LSSLKHSYSLGFVDGRYLGQGLQYGSYTDLRHPTDVLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGGGGG-GGPDLMQY-QPQP
GPGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPGSLAQYRPAVGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRR-GMYRPYVSGGVTAVPLTSLTRM
PVIAPRIPLGPTGVYRYPAPSRFPAASSVPPAEGPVYLGKPAAAKAPGAGGTP-------
----------RPELPAGVAREEPLSTATPA-AAKEALAAPA--P----APAPLATQKPPG
DAA-LGGGIGAPSRPGLEKEDTAQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPGRGPPPA--------APELAQNGQYWPPLSHT
AFI-AVAGPEGP-------GLHRGLPSSASDMSLQTEEPWEAGRG-GIKKRHSMPRLRDA
CEQESGP-EPCTVRRIADSSVQTDDEEGEGRYLLTR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAAASPSPA--------AATARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-PQGVAGPQL
VGPTAISPYLPGIQIVAPGPL----------GRFEKKKPDPLEIGYQAQLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQHGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYADFPVTA----A-AP---------ATPSGPTAFQQPRFP
-PAPQYPA-GSGGPTQNGFPAHQ----APTYAG-STYPA-PAFPPGTSYPAEPGLPGQQP
FRPTG-------HYTAQTPMPTTQSALFSVPADSRAPHQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSSPAV-SS-SYEQGKAAELPRAGDRSSVSLSSASTYPADSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPESQRLEPLGPS-SGGRPGKE-PAEPGLLEGPVL
PCCYTRGEEESEEDSYDPRGKSSH-----HRSMETNGRP--------TSTHYYGDSDYRH
GTRAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGMSSRDPVEEDDRMYGGSSR-S
RGASAYSGEKLSSHDFGGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRARPPMRSQTSEEESPVSPLGRPR----PAGGT-LPP-GDSCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPSRHASAKEHRH
HGDHGRHS-----GRHAGE-------------------EPGRRAAKPHTRDLGRHEARPH
PQPGPGPAMQKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPTAP------QPKPEP--QPQP-QGRQAAPGPQPSQPPPSRQTPSATVSRQPQT
QQQP-------------Q-QQQGLGVQP----PQQAPAQARLQQQG--------------
QQAARGPAPAT-SQPAGKAQ-PGPTTATGPQP--------AGP-----------------
----PRAEQVNGAK-GTA--------------KAPQQGRPPQAQPPPGPGPAGMKA---G
ARPGGTPGAPAGQPGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG-PLPPGGAGPGP--GP--GPGPGAGKPPSAPA----G
GGQLPAAG-------AARSTAVP---PVPG--PGPGPGPG--------------------
--PGPGSTSRRLDPKEPLGNQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPDQERS-RGPG----GP-------------------------QPGSRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPAG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFNDASK
EAGPKPLGSGPGPG------PAP--GAKTEPG----AR----------------------
------------M---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-ICPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP
LSTKA---------------------SPLPSKASPQAKPLRASEPSKTPS---------S
VQEKKTRVPTKAEPMPKPPPETTPTP---AT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMWPLLQAQGLAPS-E-RSKPLSS---GTGEEQKQRPHSLSIMPEAFDSDEELED
ILEE-DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHEMDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTTDREYG-Q
AAQPATEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSS-ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKM--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPCLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRV----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQ--EHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGVKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QPQH
GPGL-----SAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPEMPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EASGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGLGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRS-GIKKRHSMPRLRDA
CEPEPGT-EPCVVRRIADSSVQTDDEDGESRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQFVDFPATAA---A--P---------ATPCGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGASYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-GYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLDGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASTHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVE-DDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRVRPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHR-
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRASSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQIPSGAASRQPQT
QQ------------QQQQQQQQGLGLQP----PQQALTQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPSTATGPQP--------AGP-----------------
----PRAEQTNGPK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------DPKEPLGSQRAASPTPKQAS---ATAPSRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----SP-------------------------QLGSRQAE--------
---TSRATSVPGP-AQAAAPLEVGKVSPQPSF-PTKPSTAEPRPPAGEAPAKSATAVPSG
LGASEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQGQPSPSKGPPKIVFSDASK
EAGPRPPSSGP--G------PAP--GAKTEPG----AK----------------------
------------MGPG----SGPGTLAKTGGTTSPKHG-----KAEHQA-APKAAAKPKT
TPKEKA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEQTPL-PLPTSQQPPIGSPHHAAGSVPQKQKGAQGLGQPSGPMPAKASP
LPTKASPQPT-------KASPLPTKASPLPTKASPQAKPFKASESSKTPS---------S
AQEKKTGVPAKAEPVSKPPPETTLPP---GT--PKVKSGIRRIERASPAVK-AVP-EAS-
--------------------------------------------------KSGEAEEPVG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPLLEAQAAAPSAE-RSKPPGS---TTSEEQKRRPHSLSIMPEAFDSDEELED
ILEE-DEDSVQWGRQQEQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPLRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAA---PGRGLAKHGTQKGGT--RPRAEPGQEP--
----ARRLPHNATTGYEELLSEGGPAEPTD-SGGALQGGLRRFKTIELNSSGSYSHELDL
GQGPDASLDREPELEMESLTGSPEDRSRGEQSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTEMPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVGGAHGPHSGP-SQPTGP----RSQGSFEYQKASDHDYG-R
AAQPAPEGTAAS--LGTAVYEEILQTSQSIARMRQASSQDMAFPEDKK--------QEKQ
FLHADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFTTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPAFPSS-ASKEVGTSFSRA-----------PCPASLPRGYMTPTSP
AGSERTPSPSSTTYSYGQSPTTANYGSQTEELPEASSGPAAGSRAAREKALSGTDGEAGP
PHASRGYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPSLEM
PRSPGTPTSTSMVAQGTQTPHRPSTPRLVWQQTSEEAPFMVITLASEASSQTRMVHASAS
TSPLCSPTDSLP--TTHGYSQTTPPSVSQLPPE----PPGFPRA----------------
--PSAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASTVLMAQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGSRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTTQSVSLKSG-PVSEPSADP
HRAIPAELRSHA---LPGARKPHAVVVQMGEGTAGAVTTLLPEE-PANALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVADT--ALPGQSSGPFYSSRDPEPSEPPTY
RAQGVLGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRLGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDPRYGP
RGDAGSLQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GTGPDLAQY-QPQH
GPGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPRNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYMSGGATAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPNRFPISSSVPPVEGPVYLGKPA-AKAPGVGGTP-------
----------RPELPSGAAREEPHSTAAPA-AVKESVAAPTP------A--PPPGQKPPG
DGAAAGGGSVALARPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAAGRGPPPA--------APELAQNGQYWPPLTHT
AFL-AVAGPEGTGQSR-EPMLHRSLPSSASDLSLQTEEPWEAGRS-GIKKRHSMPRLRDA
CEPESAP-EPYVVRRIADSSVQTDDEDGEGRYLLTR-RRRTRRSTDCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATAASSTA--------AATARATSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDGQ-AQGVAAPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPLESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTTFASSERLNKAHVSPQKHFTTDSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPTTVPATKASLLQELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRECSPLRSLGAHRDYLSDSELNQLR
LQGS----T------TPAGQYSGFPATA----A-AP---------ATPSAPTAFQQPRFS
PPAPQYPA-GSIGPAQNELPAPQ----VPTYPGPSTYPA-PAFPSSTTYPAEPGLPNQQA
FCPSG-------HYAAQTPMPTTQSTLLPIPADSRAPHQKPRQTSLADLEQKVPTNYEVV
ASPVVAMSSAPSETSYSGPAV-SS-SYEQGKTPELPRASDRGSVSQSPVPAYPSDSHYTS
LEQSVPRNYVMIDDISELTKDS--TVADSQRMEPLGPG-SGGRPGKE-PGEPGVLEGPAL
PCCYARGEEESEEDSYDSRGKAGH----HHRGVESNGRP--------ASTHYYSDSDYRH
GARGERYGPGPVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDDRIYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYER--------------------EAVERLQKAGSKPSS
LSMAHGRVRPPMRSQASEEESPVSPMGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHLYKREEGYVLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEVGPGRHAPAKEHRH
HSEHGRHA-----GRHAGE-------------------EPGRRAAKSHVRDPGRHEARPH
PQPSSASAMLKK--------GQPGY--------PGPTDYSQPSRAPAAYHHTSDSKKGS-
RQAHSGPAAL------QPKPEPQALPQL-QGRQAAPGPQQSQPPPSRQMASGAALRQPQM
QQQQQQ----------QQQQQPGLGQQP----PQQAPSQARPQQQS--------------
QPTARGPASAA-SQPAGKPQ-AGSTTATGPQP--------AGP-----------------
----PRAEQADGSK-VTT--------------KTPQQGRAPQAQPTPGPGPAGTKA---G
ARPGGPPGAAPGQPGADGESVLSKILPGGAAEQAGKLTEGMHCLWLGLWWAALW------
-------------------------------------

-----------------------------------------------------QA----G
GGQLPAS-------GAARATAVP---PGPGPGPGPGPGPG--------------------
--PGPGSVSRRLDPKEPLSSQRAASPTPKQAS---ATAPGRESPRETR-AQGPAGQEADG
PRRTLQVDGRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQXXXXXXXXXXXXXXXXXXXXXX-----------
------XXXX-----------------------XX----------XXX------------
----------------------------------------X---------------X---
----------------------------------XXXX---------XXXXXXXXXXXXX
XXXXXXXX-XXXX----X-----------------------------XXXXX--------
---XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSATTVPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQGQPAPTKGPPKIVFSDASK
EAGPRTPGSGP--G------PAL--GAKTELA----AR----------------------
------------TGPG----SGPGAPVRTGGTTSPKHG-----RAEHQAVSKA-TAKPKT
MPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPLPTSQQQPPVGASQRAAGTASPKQKGPQGLGQPSGPLPAKASP
---------------------LPTKASPLPTKASPQAKPLRASEPSRTLS---------S
AQEKKTGIPAKAEPVPKPPPDTTLPP---GT--PKAKTGVRRTEPATSVVK-AVP-EAP-
--------------------------------------------------KGGEAEEPVG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSQLH
KVGS-SVRPSLQAQGLAPGGE-RSKPPRS---SSGEEQKRRPHSLSIMPEAFDSDEELED
ILEE-EEGSVEWRRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPPPPARA-AEM
TDEEFMRRQILEMSAEEDNLEED-DEAA---SRHGLAKHGAQKSGP--RPKPEPSQEPA-
-APPKRRLPHNATTGYEELPSEGGPAEAAD-GTGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPGLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYSLPTFMSLYSPTEVPVGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPHGGP-SQPTGP----RSQSSFEYQEPPDHDYG-R
AAQPAPDGAPAG--LGAAVYEEILQTSQNIARMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPASFPTSTSTSSDGSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEVGTAFAQGPGTP-ATTAVAPGPPGLPRGYVTLTSP
AGSERSPSPSSTAHSYGQSPTTANYGSQTEELPQAPSGPAASGRAAREKLPSVSDSKSGT
P---QGFSYFPGASPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGGPASTPMVAQGTQTPQRPSTPRLVWQQSSREAPFMVITLASDASSQTRMVHASAS
TSPVCSPTDTQP--TTHSYSQTTPPSASQLSSEPPGP-PGFPRA----------------
--PSAGADGPLAVYGWGALPAENISLCRISSIPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITPMGTAQSVGLKSG-LVPEPGAEP
HRAVPAELRSHA---LPGARKPHTVLVQVGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHAAPSVPEKSVVDV--APPGQGSSPFYNPRDPEPPEPPTY
RAQGVVGPGPHEEQRPCPQGLPGRLYSSMSDTNLAEAGLNYHAHRMGQLFQGPGRDSAVD
LSSLKQSYSLGFADGRCLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGEAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG-GGGPDLMQY-QPQP
GPGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPGTLAQYRPTAAQG-AAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPGSVLRPMVRG-GMYRPYASGGVTAVPLASLTRV
PIIAPRVPLGPTALYRYPAPSRFPTASSVPPAEGPVYLGKPAAAKVPGAGGPP-------
----------RPELXXXXXXXXXXXXXXXX-XXKEAVAAPAP--------APIAVQKLPV
DA-APGGGSGALGRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKTPFPVAC-EGPGRGPPPA--------GTELAQNGQYWPPLTHA
AFI-AVAGPEGPGQPR-EPILHRGLPSSASDMSLQTEEQWEAGRS-GLKKRHSMPRLRDA
CEPESGP-EPCVVRRIADSSVQTDDEDGESRYLLTR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAPASSST--------AASTVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVKYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPAAISPYLPGIQIVTPGTL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDASFASSERLNKAHVSPQKHFAADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYADFPVTAA---A--P---------ATPSGPTAFQQPRFP
PPAPQYIA-GSSGPTLNGFPAHQ----APTYPGPSTYPA-PAFTPGTSYPAEPGLPSQQT
FRPTG-------LYAAQTPMPTTQGTLFPVTADGRGPHQKPRQTSLVDLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SN-SYEQGKAPELPRATDRSSVSLSPAPTYPSDSHYAS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLESLGPS-SSGRPGKE-PVEPDVLEGPPL
PCCYARGEEESEEDSYDSRGKSGH-----HRSIESDGRP--------ASAHYYSDSDYRH
GARAEKYGPGPVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSGLVSRGRKFQDEITYGLKKNVYEQQRSYGVSSRDQVEEDDRVYSGSSR-S
RVTSAYSGEKLSSRDFGGRGKGFERE------------------REAVERLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPMGRPH----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDAHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----GRHAGE-------------------EPSRRAAKPHGRDLGRHEARPH
PQPSPAPAMQKK--------SQPGY--------PSSAEYSQPSRVPSAYHHASDSKKGS-
RQAHAGPAAP------QPKPEPPSQPQP-QGRQAPPGPQQSQPPPSRQTPSATSSRQPQT
-----------------QQQQQGHGLQH----PQQTPSQARLPQQG--------------
QPTARGLASAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQANGSK-GAA--------------KAPQQGRPPQAQPPPGPGPTGVKA---G
ARPGGTPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------------------------------------GPGIREVETGRGPE----G
KGQNPMGPYGPLPPQAASLSCI-------------SNSHF--------------------
--QCHFSTSRRLDPKEPLGNQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPDQERS-RGPG----GP-------------------------QPGSRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPAG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFNDASK
EAGPKPLGSGPGPG------PAP--GAKTEPG----AR----------------------
------------M---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-ICPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGELTPLPPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP
LSTKA---------------------SPLPSKASPQAKPLRASEPSKTPS---------S
VQEKKTRVPTKAEPMPKPPPETTPTP---AT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPS-E-RSKPLSS---GTGEEQKQRPHSLSIMPEAFDSDEELED
ILEE-DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHEMDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTTDREYG-Q
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSS-ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT
SQPSRAYSYFASSSPPLSPSSPSESPTFSPGKM--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPCLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRV----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQ--EHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QPQH
GPGL-----SAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPEMPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EASGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGLGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRS-GIKKRHSMPRLRDA
CEPEPGT-EPCVVRRIADSSVQTDDEDGESRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGLQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQFVDFPATAA---A--P---------ATRCGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGASYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-GYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLDGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASTHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVE-DDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRVRPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHR-
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRASSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQIPSGAPQT----
-Q------------QQQQQQQQGLGLQP----PQQALTQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPSTATGPQP--------AGP-----------------
----PRAEQTNGPK-GTA--------------KAPQQGRAPQAQPTPGPRPAGVKA---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGP------GPGPGPGAGKPPSALA----G
GGQLPAAGAA-------RAAGPPAPGLGLVPGPGPGPGPG--------------------
--PGPGSVSRRLDPKEPLGSQRAPSPTPKQAS---AAAPGRESPRETR-AQGPSGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----AT-------------------------QSGPRQAE--------
---AARATSVPGP-TQATAPPEVGRVSPQPPL-SSKPSTAEPRPPVGEAQGKSATTVPSG
LGAGEQP-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGSRPPAPGSAPG------PAP--GAKAEPG----AR----------------------
------------TGPG----PGPGAPAKSGGTASPKHG-----RADHQA-ASKAAAKPKT
TPKERA-TCPLCQAEL-NVGARGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPM-PLPTSQQPPAGAPHHAPGAAPQKQKGPQGLGQPSGSLPAKASP
QAAKAS---------------------PQATKASPQAKPLRASEPSKTSS---------S
AQEKKTGIPVKAEPVPKPPPETTVPP---GT--PKAKSGVKRTEPVTPVIK-PVP-EAP-
--------------------------------------------------KGGEAEEPVS
KPYTQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQAAAPSGE-WGKPPRS---RAVEDQKRRPHSLSIMPEAFDSDEELGD
ILEE-EDDSLAWGHQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--EM
TDEEFMRRQILEMSAEEDNLEED-DTAV---PGRGLARHSTQKGSA--RPRPESSQEPV-
-AAPKRRLPHNATTGYEELLSEGGPAEPTD-GSGALQGGLRRFKTIELNSTGTYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQQRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPARLYKSGSEYNLPAFMSLYSPTEPPSGSSTTPSSGRPLKSAEE
AYEDMMRKAELLQ-RQQGQVPGARGPHGGP-PQPTGP----RGQGSFDYQDTQDHDFG-R
ASQPAAEGTAAG--LGAAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYLDPMKQNGGPLTPGTSPTQLAAPVSFSTAT--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPLSPSL-ASKEVGMTFSQGPGTP-ATTVMAPGPASLPRGYMTPTSP
VGSERSPSPSSTVHSYGQTPTTANYGSQTEELPQAPSGPTAGGRAPREKPLSGADAEVGT
PQPSRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----SRATAEFSTQTPSATPSSDI
PRSPGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDAASQTRMVHASAS
TSPLCSPTDTQP--TSHSYSQTTPPSASQMPSEPAGP-PGFPRA----------------
--PSAGADGPLALYGWGALPDENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTQTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREPKFARYNLPNQVAPLARRDILITQMGTAQSVSLKPG-PVPEPGGEP
HRAPPAELRSQA---LPGARKPHTVVVQMGEGIAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSGPDKSVADA--ALPGQSSGPFYSPRDPEPPDPLTF
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLSYHAQRIGQLFQGPGRESAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--SGGPDLVQY-QPQH
G---------APQGLAPLRSGLLGNPTFPEGQPSPGSLPQYGPAASQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLARV
PVIAPRVPLGPAGLYRYPAPSRFPIASSIPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPELPAGSAREEPLSTAAP-AAVKEAPAAPAPAPAP----PPPPGQKPPG
DAA--AGGSGVLSRPGVEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPSRGPPPA--------APELAQNGQYWPPLTHT
AFI-AMAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEAESGP-DPGPVRRIADSSVQTDDEEGEGRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASA--A-------AAAAARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------SRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDASFASSERLNKAHVSPQKHFMTDSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHHDYLSDSELNQLR
LQGC----A------TPAGQYVDYPASA----A-VP---------ATPSGPAAFQQPRFP
PAAPQYAA-GSSGPTQNGFPAHQ----APAYTGPSTYPA-PAFPPGTSYPAEPGLPGQQA
FHPTG-------HYAAATPMPTTQSTHFPVQADSRAPHQKPRQTSLADLEQKVPTNYEVI
TSPAVTMSSAPSETSYSSPAV-SS-SYDQGKAPEHPRGGDRSSVSQSPAPAYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTAAESQRLEPLGPGGVSGRPGKE-PGEPAGLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRGLESNGRP--------ASTHYYGDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPT--PSVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPAEEDDRVYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPPFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDMGRHETRPH
PQASPAPAMQKK--------GQPGY--------PSSADYSQPSRAPSAYHHASDSKKGS-
RQAHSGSTAM------QPKPEPQSQPQM-QGRQAAPGPQQSQPQSSRQMPSGTASRQSQP
QQQQQQQQQQQ--QQQQQQQQQGVGQQA----PQQAPSQARLQQQS--------------
QPTPRGSAPAA-SQPAGKPQ-PGPTTAPGPQP--------AGL-----------------
----PRAEQASASK-AAA--------------KAPQQGRAPQAQPAPGPGPAGVKP---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEGLP-AAGGPSPSPGPGPSPGPGPAVGKAPSAPGGGQL-
----PSSGAARTVA------AQQP--PGPGPGPGPGPGPT--------------------
--ADTASMSRRLDPKDHLDSQRATSPTLKQAS---AH-SHEGRRREMR-THGQAGPQVDG
PHRTLQVDSRMQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTTDLTSSPNQ
PNFNTCTQCHNKVCNQCGFNPNPHLTEVKEWLCLNCQMQRALGMDM---TTA--------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLYSP---------SLSPAHSPAKQPQ
PQPQPQPQPQPQPQPQPKPQPPAQAQGKPEPEKIPGTTQPRLQQAPGVQQAEV-PRTPGV
LGQRE--TQSQGQ-ARPAGPQETGRISPH----------------PSPAKG---VTPTSG
PGAQEQA-QEGLTGKLFGFGASLLTQASTLMSV-QPEASPQSQPSPSKGPPKIVFSDASK
EAGPKPLGTGPGPGTARGPGPAPGSGPGAGPGPGPGSGVGPGTSPKAGPGSGPGPRPGAG
AGSKTGPGPGPAAGSKAEPGPGPGALSRPAGAPSPK-----QSKAEHQT-APKAVPKPKE
VPKEKI-TCPLCQAEL-NVGSREPPNYNTCTTCKRQVCNLCGFNPTPHLVEKNEWLCLNC
QTQRLLEGSLGDPAPVPLP-TPKQTPTSSPRHQAGPSPQKQKGPSAPGPGQQP-------
-------------------------TGPPHTSPSLQTKHLRASEPSKPPS---------V
PPEKKPSGPAEAKQVPKPSPLPTTIT-----EAPKTKDGPKRAEPLPADSKAVSIAEAP-
--------------------------------------------------RG-SEQEDPS
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGLV-QQDEEQLNTAGVVKPSPPSPSELN
KLES-SMRPLLEAQGGAPGEQAKARPP----LREEPKQRQRPRSLSITPEAFDSGEELED
ILEE-DEDSLEWENQRDPRDTAESSDDFGSKLRHDYVEDSSEGGLSPLPTRPVGRD-TEG
PDEDFMRRQILEMSAEEDNLEEDD-------TEYDRAKYSLRKTSS--KPGSEQGQEP--
-APPKRRLPHNATTGYEEELKDTGAPEPE--DVAALQGGLRRFKTIELNSTNSYGREMEM
SQEADISLDREPELEMESLTGSPEDRSRGEYSSTLPATTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEGFE-IGTSKLYKSGSEYNLPTFMSLYSPTEKVSSSASYSS-GKPLKSAEE
AYEEMMKKAELLQK-QQGQQAQPSGTYGSSR-------GTDRGQGSFEYQYIEDYDYVSS
QLGSSQPHYEPEAADAGAVYEEILQTSQSIARMHQASSQDLAFQE--EKKAAEGTYQEKQ
FLNTESAYSELMRQNGGPLTPGTSPTQLAAPMSFSS------DGGGSRLIPDVRVTQ-HF
AKEPQDA-LKLLNSPASPNA-ALKGVTTPFTYSKGTP-SITTVASSTASRPRVYTAVT--
-------AP---AGPEPPLPTTASYGSQTEEMPQAQGLPDTSGLPSRDRLQSVSDGKIIA
P-SSKGYSGFKSSSPPLSPASPMEGLPSVISR------MGPKSTSEFSTQTHSPLLPSD-
-RSPISSTPSSMVAQGTQTPHRSSSPRLTRQQSSQESPFMVITLASDAASQTKLVNAGSS
MSPDSSPTRQ--QPTVHSYSQSVQVNGTQFQQEQPL--HGFPKSERTPTSSAIIPMNAAK
GHVAPAMDGAAALYGWGSLPAENISLCRISSVPGTSRVEPGPKPPTSSAVDLRTAMKSTP
IIITDQGMDLTSLAAEARKYCLTLDQSPGRQSTTVQPLIINLNAQEHTHTFIGTSTTVSI
TVASSMLVSQPKQPVIYGDPFQNRLDFGQGTGTPVCLTQVKHVEQAVQTGPYQGGPRGKP
-----KEAGS-PQQTKFARYNLPNQMAPLVKKDILVTQMSAAQNVS--IKPYPAEPSADA
YRGVPAELKAHSMPTHLAGKKPHMMMVQMDDMTAGAVTKLVKEEP-TNALDLTGIKPESQ
VACCDVVYKFPFSSSCTGTFHPSSKMPEKNVVDT--AQPSQGALPFYGPREQDLPEPAPY
REQAMAGPRLYEEQKLYSHGLMGRLYSSMSDTNLAEAGMNYYPHKSDQFFHPPGGDSAMD
LTTMKHSYSIGFD-GRYLAQGMQYGSFTDLRQPPDLMGHPFPMRRYSSASNIYSDYRYSP
RGDLSGFQESSLAQYSATTAREISRMCAALNSMD-QYGGRHS-----SSPELLQYG-PRP
GPGA-----GAQQGLAALKPNMMVNPNFPEGRQSFGKLAQYNPAAGQGGGAIRQLFPSTA
TVRAADGMIYSTINTPIASTLPITTQPASVLRPMVR--GIYRPYGPGSITPVPLASLTRV
PVVAPRVPLMPQGLYRYPPPGRFPALTTAPGMEGPLYLGKAGPATSIAGSSVPPGPTGKP
AVAAAAGGLQRTEQPVGSAREE----PPAA--------ASGTAKEAGPAPVHLPGQKQPE
AS-PA--VL--LGKAGGAEKEEKEEERQRKQQEHMLQMERERVELEKLRQLRLHEELERE
RVELQRHREKEQMLVQREIQELQTIKHQVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQK-RQKAPFPPVC-DPSGRLPPQAVTEITLEMQRTMAPNGQYWPPINQA
FMATAAVGIE--GQPR-EPGPPRPLTNSASDMSLQTDEHWEAGRG--LKKRHSMPRLRDA
YEMEEAHEQPYVVKKITDSSVQTDEEDGEERYFMSR-RRRTRRSTDCSVQTDDEDNAEWE
QPVRRRRTRFSRHSDSTSDSKHEASSSS--------------PRGKSSVGIQTISDCSVQ
TEPDQLLRVSPSIHITT-PDPKVEIIKYISAPEKTQKGESLACQTEPEAQ-TQGIVVPQL
TGPAAITPYTPSIQIVTTEP------RQQGLGKFEKKKPDPLEIGYQSHLPTESLSQL-V
TRQPPKSPQVLYSPVSPLSPHRLLESSFASSERLNKAHVTPQKHFTADSTQRQQTVPRPM
KTMQRSLSDPKPISPTAEESAKERFSLYQQQVLQGSQMSAFQANTLIRKVKRTLPSPPPE
EAHMPLPSQA-HSQMYLAGLLQKGLAGPP-VQVTKASLLKELDRDLKLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKGSLMKDR-VGRDYPYLQCLGENRDYMSDSELNNLR
LAGYESGAVHVRPSTAPTNQYSDFAATQYTSASSYPPYQYPPGQGPPPPPPTAFQHTRFQ
PP--QYPV-GVAGPAQNGFQASQ----VAAYPPQSTYPA-PAYPPSAGYPAEHSLPGQQN
FRPAPPHYQPQTTYPGQMAHPPPQNALYPDPADSHASHQKPRQTSLADLEQKVPTNYEVI
ANPPTVMSSAPSEPTYSAPAVT--STYDQYKAPEPPRAGDRSGVSQSPGPAYSSESLYTN
LEQNIPRNYVMIDDISELTKDSTPSAVESQKPEPRPQG-SNGRHVKD-KSDLGEPEGPGV
PCCYSKGEEESEEDVYDHHGTDHRGKSSYHRGSESNGRMSGSG---GGSSYYYGESDYRH
SSRPEKHGSSMGGPKHSSKNLAPAVISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPTTTSVSS-SMSSRGKKFQDEITYGLKKNVYEQQKYYGVSSRDLVEEDDRPYGGGRSRS
--STSYSSD-KSSHDMSSRSKSYERER----------------ERDSMERLQKTSSKPSS
LSMSQSRGRPPMRSQASEEESPISPLGRSVGGPRSSGGPLPPGAGDGCSPFCSS-HSLPD
VQEHI-KDVPRTHSYKHEEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-EAR
SERLRHHGGHSSS--S-SSQKRPPVKHTYHDYD-EPPEEDLWPHDEGPQGRHS-SKEHRH
HGDYGRHSSGSSSSRHQGE-------------------EPSRRVSKPHPRDSGRHEGRPH
SQPSSQKKAQQADPR-----GQPSYP-------SSQSEYSQPSRQPAAYHHPSEPKKAQR
SM---QSGPSA----QPPKSETLAHSQPQQARQPQSGPSQQQLPPQSS------------
------RQQQSRQPPSQQQQQMSHGPQPT-----QSQ--TQQTP--------SQARLQ--
---QQQGMPGQPSSRGQQPP--SGQQ-----A--G------------KAMPGHPPSASAQ
PAGPLKAEQLDSSKPTAKVQQQQQQQQQQQQQQQQQQGRVPHAQPQ-GATTTGTKVGAKP
GGVPPASGAPTGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGVGDG-LLPPGGPGP------GPGPGPGAGKPPSAPV----G
GGQLPVAG-------AARVTPGP---PVSGPGPGLGPGPG--------------------
--PGSGSISRSLDSKEPVDSQRAASPTPKQAS---TAAPGRESPRETR-AQGSAGQEADG
PC KALQVDSRTQRTGRSPSVSFSAE---GRPCNDPQIAPLP SSTLCPICKTSDLTSTPSQ
PNFNTCTQCHSKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GP-------------------------QPVPRQAE--------
---TARATSVPGP-APAAAPPEMGRASPQPSL-PTKPSTAEPRPPPGEATAKSATVAPSG
AGAAEPT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQPAPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PAP--AAKTEPG----AR----------------------
------------TGPG----SGPGALAKTEGTTSPKHG-----RAEHQAASKA-TAKPKT
TPKERA-ICPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTE-LCLNC
QTKRLMEVREREPPQLFCFSWEFW--GAAPRAAVGSPRNRP-------------------
------QWPSSSGFLV---------EVSLQTFKASALVPTRASDTSLTPS---------S
AQVKKPGAPAKATTVPKLPPEATPPT---GT--PKVKSGVRRNDPATPVAK-AVP-EAP-
--------------------------------------------------KGGEAEEPVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPVELH
KVGS-SVRPQLEAQGLAPSGSERSKLLSS---SVSEEQKRRPHSLSIMPEAFDSDEELED
ILEE--EDSLQWQRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPVPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEDD-DTAT---PGHSLAKHGAQKGSS--RTRPEPGQEVA-
-ALPKRRLPHNATTGYEELLSEGGPPEDTE-SSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GAPSRLYKSGSEYNLPTFMSLYSPTETPVGSATTPSTGRPL KSAEE
AYEEMMRKAELLQ-RQQGQGMAAKGPHG GP-SQTPGP----RGQGSFEYQDTPD RDYG-R
ATQPAPEGSPAG--LGKAVYEEILQTSQSIARMRQASSRDLAFAEDKR--------KEKQ
FLNAESAYIDPMKQNGGPLTPGTSPTQLAAPVSFSAS--TTSDSGGGRVIPDVRVTQ-HF
AKEPQDT-LRLHSSSASPSS-APKEVGMSVSQGPGAP-ATTAAAPCPAGLPRGYMTPASP
AGSERSPSPSSAGHAYGTSPSTANYGSQTEELPPAPSGPAASGRAAREKPLSGTESEGGA
PQPSRGYSYFAGSSPPISPS SPSESPTFSPGRL--G----HRATAEFSTQTPSPAPALDM
PRSPSAPTPTPMVAQGTQTPHRSSTPRLVWQQSSQEAPIMVITLASDASSQTRMVHASAS
TSPPSSPTDTQS--TAHSYSQTTPPNGSQMPPEPPGP-PGFPRG----------------
--PSAGTDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAAEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMSSSVLMGQQKQPGVYGDPFQNRLDFGQGAGSPVCLGQGKQVEQAVQTAPYRGGARG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGLKAG-PVPEPGAEP
HRVTPAELRSHA---LPGARKPHTVVVQMGEGPAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFSSSCTGAFHPTPSAPEKSGSET--VPPGQGSGPFYGPRDSELPEPPIY
RAQGIMGPGPHEDQRPYPQGLPGRLYSSMSDTNLAEAGLGYHAHRIGQLLQGSGRDSALD
LSSLKHSYSLGFADGRYVGQGLQYGSFTDLRHPTDL-THPLPMRRYSSVSNIYSDHRYGA
RGDTVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGGVG--SSPDLAQYHQPQH
GPGL-----SAPQGLAPLT--LLGNPTFPDSHPSPGNXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAAKALGTGG-H-------
----------PPEPPAGTAREEPVPTTTPA-AIKEAAPAPAP--------APLAGQKPPG
DAAAPGAGSTTLSRPGPEKEELSQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPSRGPPPT--------APELAQNGQYWPPLSHT
AFI-AVAGPEVPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRG-GIKKRHSMPRLRDA
CESEPGP-EPGTVRRITDSSVQTDDEDGEGRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRARASRHSDSTSDSKHDTTASTSTAST-----ATAAARATSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIKYISAPEKTGRGESLACQTEPDAQ-VQSVTGTQL
VGPTAISPYLPGIQIVTPGSL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-M
GRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFAAESTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PQQLYAASLLQRGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAAPYVDFPTAAA---APTP---------TTASGPTAFQQPQFP
PPTTQYTS-VSSGLTQNGFPAHQ----APSYPGPNTYPT-SAFPPGTNYPPEPGLSIQQA
FRPTG-------HHTAQTTMPTTQSTHFPISAESRVPHQKPRQTSLADLEQKLPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-SYEQGKGPELPRASDRSSVSQSPVPAYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTAPESQRLDPMGPG-SSGRPGKE-PGEPGALEGPTL
PCCYGRGEEESEEDSYDPRGKAGH-----HRSVESNGRP--------ASTHYYSDSDYRH
GTRAEKYGPGPLGPKHPA KSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEARDVESDLAS
YPP--SAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDDRVYAGSSR-S
RVASAYSGERLSSHDFSSRSKGYERE------------------RETAERLQKAGPKPSS
LSMAHSRGRPPMRSQVSEEESPVSPMGRPR----PAGGP-LPP-GDSCPQFCSS-HSMPD
VQEHI-KDGPRAHTYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVS----SSQKRGPARHSYHDYD-EPPEEGLWPPDEGGPGRHASAKEHRH
HSEHGRHS-----GRHAGE-------------------EPGRRAAKSHGRDMGRHEA RPH
PQPSTAPAMPKK--------GQPA Y--------PSSAEYSQPPRTPSAYHHAPDSKKGS-
RQAHSGPSAL------QPKPEPQAQPQL-P-RQTTPGPQQSQPLPSRQLPSGAAARQPQV
QQAPPPQQ------PLQQQ------QQT----PQQAPSQARQQQQS--------------
QPSARGPGPAA-SQPAGKPQ-P GPTIAAGPQT--------AGL-----------------
----PRADQANGSK-ATA--------------KAPPQGRAPQAQATPGPAPAGVKS---G
ARPGGTTTTPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------TSRRLDPKEPLGSQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPDQERS-RGPG----GP-------------------------QPGSRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPAG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFNDASK
EAGPKPLGSGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAVSKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLLPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP
L----------------------------STKASPQTKPLRASEPSKTPS---------S
AQEKKTRVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLAG
KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPS-E-LSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQTPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGHGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RSPGSFEYQDTADREYG-Q
AAQPAAEGTPAG--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPNEA--------KCPTQLAAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSKRSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKM--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRV----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTTVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVTPLARRDVLITQMGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMER-----------------------------
------------------------------------------------------------
------------------------------------------------------------
AHSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG---GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPEMPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKPPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEPSRS-GIKKRHSMPRLRDA
CEPESGA-EPCVVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATVSSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGIAGSQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SLSPLSPHRERLXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXSASKTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQFVDFPAPAA---A--P---------ATPSGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGASYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-GYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGETGVLEGPTL
SCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASTHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSSRDAVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKVGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSTYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQIPSGAQQ-----
QQ------------QQQQQQQQGLGLQP----PQQALTQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPAGQPGADGESMFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------------------------------MRKNLQKRLER-----CGQA----G
GGNSGEGGIPEADS--LRC---------------ISNSHF--------------------
--QCHFSTSRRLDPKETLGSQRTASPTPKQAS---ATTPGQESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSRQGE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKVAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGASPLKQKGSQGLSQPSGPLPAKASP
LS---------------------TKASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRKAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDAVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGDP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGS-SQPTGP----RGLGSFEYQDTTDRDYG-R
AAQPAAEGTPTS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSRGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLLRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESGA-EPCVVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPTDSHAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETIYSGSAV-SS-GYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------AGTHYYADSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTLEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEDGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQSQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
QQQQQQQQ------QQQQQQQQGLGLQP----P------------H--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPARQPGADGESMFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------MGNEASLEGGAGDGPLPPG--G--------AGPSAGKPPSAPSGGGQL-
-PAAAATRAT-------AG------PPGPG--PGPGPGPR--------------------
--LGPDSISWRLDPKEPLGSQRTASPTPKQAS---ATALGHERPRETR-AQGPAGQEADG
PCRTLQVDSRMQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQEHS-WGPG----GP-------------------------QLGSRQAE--------
---TSRATSVLGP-AQAAAPLEVGKVSPQPSL-PTKPSTAEPRPPAGEAPAKSATTVPSG
LSASEQT-QEGLTGKLFGLGASLLTQASTLISV-QPEADPQGQPSPSKGPPKIVFSDASK
EAAPRPPSSGP--G------PAP--GTKTEPG----AR----------------------
------------MGLG----SGPGTLAKTVGMTSPKHG-----KAEHQA-APKTAAKPKT
IPKEKA-TCPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEQTPL-PLPTSQQPPIGAPHHAAVSAPLKQKGPQGLGQPSGPLPTKASP
LPTK--------------ASPLSPKSTPLPNKASPQAKPVKAPESSKTPS---------S
AQEKKTGVPAKAEPIPKPPPETTLPP---GT--PKVKSGVRRIDRATPVVK-AVP-EAS-
--------------------------------------------------KSGEAEESVG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SVWPLLEAQAVAPSAE-QSKPPCS---SAGEKQKRRPLSLSIMPEAFDSDEELED
ILEE-DEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSESGLSPLPPQPPLRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAA---SGRGLTKHSTQKGST--RPRPEPGQEP--
----ARRLPHNATTGYEELLSEGGPAESTD-SGGALQGGLRRFKTIELNSSDSYSHELDL
GQGPDAILDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTEIPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVVGAHGPHGVP-SQPTGP----GGQGIFEYQDAPDRDYG-R
GAQPAPESTAAS--LGTAVYEEILQTSQSIARMRQASSQDLAFPEDKK--------KERQ
FLNADSTYMDPMKQNGGPLTPGTSPTQLAAPMSFTTST--SSDSSGGRVIPDVHVTQ-HF
AKEPQNS-LKLHSSPATPSS-ASKEVGTSFSQGLGTP-ATTAVAP-------WYITSTSP
DGSERTLSPSSTAYSYGQSLTTANYGSQTEELPEASSGSAVGSRAAREKALRRTDGEAGP
PRASWGYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPIPSLEM
PRSPGTPTSTSMVAQGTQTPHRPSTPRLVWQQTSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--ITHSYSQTTPPSVSQLPSQPPGPPPGFPRV----------------
--PSAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRHPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGNATTVSI
TMASSVLMAQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRSGSRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTTQSVSLKSG-PVSEPSAEP
HRAIPAELQSHA---LPGARKPHAVVVQMGEGTAGTVTTLLPEE-SASALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVADT--ALPGQSSGPFYSPQDPEPSEPPTY
RAQGVMGPGPHEEQRSYPQGFPGRLYSSMSDTNLAEAGLNYHAHRVGQLFQGPARDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPIRRYSSVSNIYSDHRYGP
QGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GTGPDLVQY-QPQH
EPGL-----SAPQGLAPLRPGLLGNPTFPESHPGPRNLAQYGPAPGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGPTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPIPNRFPISSSVPPAEGPVYLGKPA-AKAPGVGGYP-------
----------RPELQAGAAREEPYSTAAPA-AVKESVAAPTP------TPALPSGQKPPG
DAAAAGGGSVTLGRPGLEKEDASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-DAPGRGPPPA--------APELAQNGQYWPPLTHT
AFL-AVAGPEGSGQSR-EPVLHRGLPSSASDLSLQTEEPWEAGRS-SLKKQHSMPRLRDA
CEPESAP-EPYVVKRIADSSVQTDDEDGEARYLLTR-RRRTRRSTDCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------TTTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKVHVSPQKHFTTDSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EGHLPLAGQA-PPQLYAASLLQRGLAGLTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
EELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRECSPLHGLGVHRDYLSDSELNQLR
LQGC----I------TPARQYAGFPATA----V-AP---------ATPSVPTAFQQPRFL
PPAPQYTV-GNIGPAQNELPAHQ----APTYPGPNTYPA-PAFPPSTSYSAEPSLPNQQA
FCPSG-------HYASQTPMPTTQSTLLPVPADSHAPHQKPRQTSLADLEQKVPTNYEVI
PSPVVAMSSAPSETSYSGPVV-SS-SYEQGKAPELPQASDCGSVSQSPVPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTVPDSQRLESLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEE-SEEDSYDSRGKAGH----HHRTMESNGRP--------ASTHYYSDSGYKH
GARVEKYGPGPVGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--TAVISSPASRGRKFQDEITYGLKKNVYEQQRYYGVSTRDIAEEDDRMYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------REAVDRLQKAGPKPSS
LSMVHGRARPPMRSQASEEESPVSPLGRPR----PTGGT-LPP-GDTCSQFCSS-HSMPD
VQEHV-KEGPRAHSYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHGPAKEHRH
HSEHGRHT-----GRHAGE-------------------EPGRRTAKSHARDLGRYEARPH
PQPSLTPAMLKK--------GQPGY--------PGPTDYSQPCRGPVAYHHASDSKKGS-
RQAHSGPAAL------QPKPEPQAPPQL-QGRQAAPGPQQSQPPTSRQMPSGAALRQPQM
QQ---------------QQQQPGLGQHP----PQQASSQARPQ-QS--------------
QPTARGPASSA-SQLAGKPH-PGSTTAPGPQP--------AGS-----------------
----PRAEQADGSK-VAA--------------KTPQQGRASQAQPTPGPGPAGTKP---G
ARPGGTPGATPGQPGADGESVLSKILTGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SVSRRLDTKEPLGSQRAASPTPTQAS---ATAPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPERGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKGEPERS-RGQG----GP-------------------------QPSPRQAE--------
---PARATSVPGTA-PAAAPLEVGRVSPQPSL-PIKPSTAEPRPPAGEAPAKSATAVPSG
SGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADSQGQPSPSKGQPKIILSDASK
EAGSRPPGSGTRPG------PVP--GAKTEPG----AR----------------------
------------TAPG----SGPGALARTGGTTSPKHG-----KAEHQAVSKA-AAKPKT
MPKERA-TCPLCQAEL-NVGSKAPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTERLLEGSLGELTPLPVPTSQ-QPPVGAPHRTAGTAPLKPKGLPALGQPSGPLPTKAGP
---------------------LPAKASPLPAKASPQAKPPRVSEPSRTPS---------S
AQEKKAGIPTKAEPVPKPPPETTPPP---GT--PKAKSGTRRTEPATPVSK-AVP-EAP-
--------------------------------------------------KGGEAEELVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPRPPSSSELH
KVRS-SMRPLLEAQGLAPSGK-QSKPLSR---SNGKEQKRRPHSLSIMPEAFDSDEELED
ILEE-EEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQAPAQV-AEL
TDEEFMRRQILEMSAEEDNLEEE-DAAT---SGHGLAKHSTQKG-D--RPRAEPTQESV-
-ALPKRRLPHNATTGYEELLSEVGPAEATE-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDSGLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTEMPSGGSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQVAGAQGPLGGS-SQPTGP----RGQGSFEYQDTLDHDYG-R
AAQPASESTSAS--LGAAVYEEILQTSQSIARMRQASSRDLTFAENK---------KEKQ
FLNAESAYMDPMRQNGGPLTPGTSPTQLAAPVSFSTSTSTSSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKIHSSPVSPSS-ASREVGVPFSQGSGVP-ATTALAPCPASLPRGYVTPTSP
AGSGRSPSPSSTGHSYGQSPTTANYGSQTEELPQAPSGPAAGGRAAREKPLISG-GQSSI
SQSSWGYSYFVGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSTTPASDM
PRIPSASTATPMVAQGTQTPHRPSTPRQAWQQSPQEAPFMVITLASDASSQTRMVHASAS
TSPVCSPTGSQP--TTHSYSQTTPPSVAQLPPEPPGP-PGLPRA----------------
--PSAGTDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAAEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQPKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKHVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLVRRDVLITQMGTAQGVGLKPG-LVSEPGAEP
HQATPADLRPHA---LPGARKPHTVVVQLGEGTAGTVTTLLPEE-PASALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSAPEKGVADA--APPGQSSGPFYGPRDPEPPEPPSY
RAQGVVGPGPHEEQRPYPQTLPGRLYSSMSDTNLAEAGLNYHAHRLGQLFQGPRRDSAVD
LSSLKHSYSLGFADRSYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDVAGFQDASLAQYSATTAREISRMCAALNSMD-QYGGRHGSSG--GGPDLMQY-QPQP
GPGL-----SVPQGLAPLRPDLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPTSVLRPMVRGGGMYRPYASGGVTAVPLTSLARM
PLIAPRIPLGPTGLYRYPAPSRFPTASSVQPAEGPVYLGKPAAAKAPRAGGPP-------
----------RPELPSGPAREEPLSTATPA-AVKEAAAAPAP--------ALLTAQKPPG
DA-APGPGSGALSRPGHEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREE--------------------------------------------------
-----------------APFPVAC-EAPGRGAPPA--------AAELAQNGQYWPPLTHA
AFI-AVAGPEGPGQPR-EPVLHRGLSSSASDMSLQTEEQWEASRS-GIKKRHSMPRLRDA
CEPESGP-EPGMVKRIADSSMQTDDEDGESRYLLTR-RRRTRRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDASASSST--------TAAASRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDAQ-AQGAAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLASQA-PPQLYAASLLQRGLAGPTAVPATKVSLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPTGQYADFPAAA----L--P---------TAPSGSTAFQQPRFP
PSAPQYSA-GTSEPTQNGFPSQQ----APTFPGPGTYPA-PAYPAGTSYPAEPGLPSQQA
FRPTG-------HYAAQTPMATTQSTHFPVPADSHTPHQKPRQTSLADLEQKVPTNYEVI
PSPVVAMSSAPSDTSYSGAAV-SS-NYEQGKAPELPRASERSSVSQSPATTYPSDSHYTS
LEQNVPRNYVMIEDISELTKDSTSTAPDNQRLEPLGPG-GSGRPGKE-PGEPGVLEGPAL
SCCYARGEDESEEDAYEPRGKGGH-----HRSMDSNGRP--------ANAHYYSDSDYRH
GARAEKYGPSPMGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLGSRGRKFQEDITYGLKKNVYEQQRYYGASSRDSVEDDDRMYGGGSR-S
RAVSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDSHCVVSDSEGNGSLGSLKHI----TGPDKPRGCPA
LDRFRHHGGHAVSSSS-SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSTKEHRH
HSDHGRHS-----GRHTSE-------------------EPGRRAAKPHVRDPGRHEARPH
PQPGPAPAMQKK--------GQPGY--------PSSAEYSQPSRTPSAYHHAPDSKKGS-
RQAHPGPPAL------QPKPEPQLQPQS---RQAPLGSQQSQPLLSR-------------
-------------------------PGP----SQQAPSQARLQQQG--------------
QPAARSPAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRTEQASGSK-GTA--------------KAPQQGKPPQAQLPPGPGPAGMKA---G
ARSGGTPG-PAGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGD---------GPLPPGGPGPGPGPGTGKPPSAPA----G
SGQLPTS-------GTARATPGL---QVSG------------------------------
--AGPGSVSRRLDPKEPLGSQRAASPTPKQAS---ATTPGHESPRETK------AQEVDG
PSRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQEKS-RGPG----GP-------------------------QPGLHQVE--------
---TSRATSAPGP-AQAASSSEVGRVSPQPPL-PTKPSTAEPRPSAGEALAKSATTVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQSQPSPNKGPPKIVFSDASK
EAGPRPPGSWPGPG------PAP--GAKTEPG----AR----------------------
------------ASPG----SGPGALVKTGGTTSPKHG-----RAEHQAASKA-TAKPKT
TPKEKA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLMEGSLGEQTPLPLPTSQ-QPSAGVPHRAT-AVPLKQKGPQGLSQPSGPLPAKASP
PLTK--------------ASPLPTKASALPTKASPQAKPLKASEPSKTPS---------S
AQEKKTGVPAKAEPMPKPPPETTQIP---GT--PKLKSGVKRTEPATPVIK-AVP-EAP-
--------------------------------------------------KGGEAEEPVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGN-SMRPLLEAQTVPSSGE-QSKPPSS---STGEEQKRRPRSLSILPEAFDSDEELED
ILEE-EENSLEWGRQREQRDTAESSDDFGSQLRHDYVEDSSESGLSPLPPQPPVRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTST---SGHSLAKHGTQKIGI--RPRPEPSQEPV-
-ALPKRRLPHNATTGYEELLSEGGPAEATD-GNGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPTRLYKSGSEYNLPTFMSLYSPTELPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVAGARGPDGGP-PQPTGP----RGQGSFEYQDTPDRDYG-R
AAQPATEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFTEDKR--------KEKQ
FLNAESAYIDPMKQNEGPLTPGTSPTQLAAPVSFSTS--TSSDSSGGRVIPDVRVTQ-HF
AKEPQEP-LKLHSSAASPSS-A-SEVGMSFSQGPGTP-ATTAMASCPASLPRGYMTSTSP
ASSERSPSPSSTVHSYGQSLTTANYGSQTEELSQAPSGPAAGGRTTREKPLSGSDIEAGT
PQPSRIYSYFAGSSPPLSPSSPSESPTFFQGKL--G----SRTTAEFSTQTPSPTPAPDM
PRSPGAPTSTPMVAQGTQTPHRPSTPRMVWQQSSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTDTLP--TAHSYSQTTPPSVSQLPPEP----PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAMEARKYGLALDPVPGRQSTTVQPLVINLNSQEQTHAFLGTTTTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDILITQMGTTQSISLKPG-PVPEPGAES
HRATPAELRSHA---LPGARKPHTLVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVADA--APPGQSSSPFYSHRDLEAPEPPTY
RAQGVVGSGPHEEQRPYPQSLPGRLYSSMSDTNLAEAGLNYHA-RLGQLFQGPGRDTAMD
LNSLKHSYSLGFIDGRYIGQGLQYGSFTDLRHPTELLTHPLPMRRYSSVSNIYSDHRYGP
RGDTVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--SGPDLVQY-QPQH
GHGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPGNLAQYGPTAGQG-TAVRQLMPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIVSSVPPAEGPVYLGKPAATKAPGAGGPP-------
----------KPELPAGAAREDPLSTTAPT-AVKEAVIAPAS--------APPPGQKPPG
ES-ATGGSSGVLSRTVLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQMLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPSRGPSTG--------TTELAQNGQYWPPLTHT
AFI-AVGGPEGPGQPH-EPVLHRGLASSASDMSLQTEEQWEAARS-SIKKRHSMPRLRDI
CEPESGP-EPCVVRRIADSSVQTDDEDGEGRYLLTR-RRRPRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATAVSST--------AATTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAVTDPKVEIIRYISAPEKTGRGESLACQTEPDGQ-AQSMPGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESSKERFSLYQHQGVLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLTGPTTIPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LPSS----T------IPAGQYVDFPATAA---V--P---------ATPSGPAAFQQPRFP
PPAPQYTP-GGSGPTQNGFPAHQ----TPIYPVPSTYPA-PTFPPSTSYPAEPGLPNQQA
FRPTS-------HYAAQTPMPTTQSTLFPVPTDSRAPLQKPRQTSLADLEQKVPTNYEVI
TSPVVAMSSAPSETSYSGSTV-SS-SYEQGKVTELSRTSDRSSVSQSPAPTYPPDSHYTS
LEQNVPRNYVMIDDISELTKDNTPTVPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDTRGKVGH-----HRSMENNGRP--------ASTHYYSDSDYRH
GARAEKYGPGPVGPKHPSKSLAPAAIPSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--SAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQTSEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----TQKRGSARHSYHDYD-EPPEEGLWPHDEGGSGRHASAKEHRH
HSEHGRHS-----GRHAGE-------------------EQGRRAAKPHVRDMGRHEARPH
PQPSPAPAMPKK--------GQPGY--------PGSGEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAQ------QPKPESQAQP---QGRQVAPGPQQSQPPASRQTPSGAASRQPQ-
--------------T---QQQQGLGQQP----PQQAPSQTRLQQQS--------------
QPITRGPASA-SSQPTGKPQ-PSSMTAPAPQP--------GGL-----------------
----PRAEQTNGSK-VTA--------------KAPQPGRAPQAQPTPGPGPTGMKT---G
ARPGGTPGASAGQPGTDGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SMSRRLDPKDHLDGQRSTSPTPKQAS---AH-SHEGRRREMR-THGQAGPQVDG
PHRTLQVDSRMQRTGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTTDLTSSPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTEVKEWLCLNCQMQRALGMDM---TTA--------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLYSP---------SLSPAHSPAKQSQ
PQPH---------------------------QPQP-QPQPPAQQGPGVRQAEV-PRSPVV
PGQRE--AQSQSQ-ARPAVPQDSGRVSPHT--------------HPSPAKG---ATPTPG
SGAQEQA-QEGLTGKLFGFGASLLTQASTLMSV-QPEAGPQGQPSPSKGPPKIVFSDASK
EAGPKPSGTGPASA--------PGTGA---------------------------------
-----GRGPGPK----SEPGSGPGALGRPAGAASPK-----QSKAEHQT-TPKAVPKPKE
VPKEKV-TCPLCQAEL-NVGSREPSNYNTCTTCKLRVCNLCGFNPTPHLVEKNEWLCLNC
QTQRLLEGSLGDPAPVPLP-TPKQTPTSSPRHQASPSPQKQKGPPAPGPGQ---------
---------------------------TPHTSPSLQTKHLRTSEPSKPPG---------G
PQEKKPSGPAEAKQVPKPSPLPSTLT-----ESPKMKDGPKRAEPPPADSKVPLPPERS-
-------------------------------------------------LNGLFALQDPS
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGLV-QQEEEQLNTAGVGKPGPPSPSELN
KLES-SMRPLLEAPGGAPGEPAKARPQ----QREEPKQRQRPRSLSITPEAFDSDEELED
ILEE-DEDSLEWEKQRDARDTAESSDDFGSKLRHDYVEDSSEGGLSPLPARPAGGD-AEG
-DEDFMRRQILEMSAEEDNLEEDNLEEEEEGADYERAEFGLRKGGA--KAGPEQGPEA--
-AAPKRRLPHNATTCYEEELKEAGAPEPE--DVAALQGGLRRFKTIELNSTNNYSREMEL
SQEADISLDREPELEMESLTGSPEDRSRGEYSSTLPATTPSYTSGTSPTSLSSLAEDSDS
SPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEGFE-MGPSKLYKSGSEYNLPTFMSLYSPTEKAAGGPSYPS-SKPLKSAEE
AYEEMMRKAELLQK-QQGQQAP----------------PSGRGQGSFEYQYIEDYEYASG
Q---SQPRYEPEAADAGAVYEEILQTSQSIARMHQASSRDLAYQE--EKKEREDAYQEKQ
FLNAESAYSELMRQNGGPLTPGTSPTQLAAPLSFSS------DSGGSRLIPDVRVTQ-HF
AKEPQDA-LKLLSSPASPSS-ALKGVTAPLTYSKGTP-SVTTVASSTAGRPRVYTAAT--
-------SP---AGQEPSLPTTASYGAQTDEMLQAQVLPDTCGLPSRDRLQSVSDGKPSA
PLSSKSYPGFKSASPPLSPTSPMEGLPSAIGR------MGPKSTAEFSTQTHGPLLPSDV
PRSPVGPAPSSMVAQGTQTPHRSSSPRLTRQQSSQESPFMVITLASDAASQTKLVNASSS
TSPASSPTRH--QPTIHSYSQSVQVNGAQLLQEQSL--HSFPKGERTPT-----------
----STMDGTAALYGWGSLPAENISLCRISSVPGTSRVEPGPKPPTSSAVDLRTAMKSTP
IIITDRGMDLTSLAAEARKYCLTLDQSPGRQSTTVQPLIINLNAQEHTHTFIGTSTTVSI
TVASSMLVSQPKQPVVYGDPFQNRLDFGQGTGSPVCLTQVKHVEQAVQTGPYQGGPRAKP
-----KEAGS-PQQTKFARYNLPNQMAPLVKKDILITQMSPAQNVS--IKPYPAEPSSDA
YRGVPAELKAHSVPPQLGGKKPHMMMVQMDDMATGAVTKLVKEEP-ASALDLTGIKPESQ
VACCDVVYKFPFSSSCTGTFHPSSKMPEKNVADT--AQPSQSTLPFYGPREQDLPEPSQY
REQA-VGPRLYEEQKLYSHGLMGRLYSSMSDTNLAEAGLNYYPHKSDQFFQPAGGDSAMD
LTTMKHSYSIGFD-SRYLAQGMQYGSFTDLRQPPDLMGHPLPMRRYSSASNIYSDYRYSP
RADLAGFQESNLAQYSATTAREISRMCAALNSMD-QYGGRHS-----SSPELLQYG-SRP
GPGA-----GAQQGLAAIKPNMMINPNFPEGRQSFGKLAQYSPAAGQGAAAIRQLFPSTA
TVRAADGMIYSTINTPIASTLPITTQPASVLRPMVR--GIYRPYGPGTITPVPLASLTRV
PVVAPRVPLMPQGLYRYPPPSRFPAITTAPGIDGPLYLGKAGPATTVAGSSLTPGP----
------AGKPVAGAAGPAPA-------------------------------HLPGQKQPG
EA-PPVAVL--A-KAGGAEKEEKEEERQRKQQEHLLQMERERVELEKLRQLRLHEELERE
RVELQRHREKEQMLVQREIQELQTIKHQVLQQQQEERQAQFALQREQLAQQRLQLEQI-Q
LQQQLQQQLEEQK-RQKTPFPPVC-DPSGRLPPQAVTEIALEMQRTMAPNGQYWPPINQA
FMATAAMGMEGTGQQR-EPGPPRPLPSSASDMSLQTEDHWEAGRG--LKKRHSMPRLRDA
YEMEESHE-PYVVKKITDSSVQTDEEDGEERYFMSR-RRRTRRSTDCSVQTDDEDNADWE
QPVRRRRTRFSRHADSVSDSKHDS--SS--------------PRSKSSVGIQTISDCSVQ
TEPDQLLRVSPSIHITT-PDPKVEIIKYISAPEKTQKGESLACQTEPEAQ-AQGIVVPQL
PGPAAITPYTPSIQIVTTGPLEP---RQQGLGKFEKKKPDPLEIGYQTHLPTESLSQL-V
TRQPPKSPQVLYSPVSPLSPHRLLESSFASSERLNKAHVTPQKHFTADSAQRQQTVPRPM
KTMQRSLSDPKPISPTAEESAKERFSLYQQQVLQGSQMSAFQANTLIRKVKRTLPSPPPE
EAHMPLPSQA-HSQMYMASLLQKGLAGPP-VQVTKASLLKELDRDLKLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKGSLMKDR-VGRDYPYLRCLGENRDYMSDSELNNLR
LTGYESGAVHY----PPG---------------------Q-----GPPPAPPAFQHSRFQ
PP--QYPV-GSAGPPPNAFQPTQ----VPAYPAQSTYPA-PAFPPSAGYPPEHGLQGQQN
FHPAP-HYQPQTTYPGQIPHPAPQNALFPEPADSHAAHQKPRQTSLADLEQKVPTNYEVI
TAPPTAMSSAPSEPTYSAPAVT--SSYDQYKAPEPPRPSDRSGVSQSPGPPYSSESLYTN
LEQNIPRNYVMIDDISELTKDSAPSAGEGPKPEPRPPG-VNGRHLKD-KSDLGEPEGPGV
PCCYSKGEEESEEDVYDHHGTDHRGKSSYHRSSESEGRISGSA---GGSSYYYGDSDYRH
SSRPEKHGSGLGGPKHSSKSLAPAVISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPPAPSVSS-SMSSRGKKFQDEITYGLKKNVYEQQKYYGVSSRDLMEDEDRAYGGRSR--
---AGYGSDK-AGHDMSTRAKAYERE------------------RDGMERLPKGSSKPSS
LSMSQSRGRPPMRSQASEEESPISPLGRSVGGGRSSGGPLPPGAGDGCSPFCSS-HSLPD
VQEHI-KDVPRTHSYKHEEGYNLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-ESR
SERLRHHGGHSS-----SSQKRPPVKHTYHDYD-EPPEEDLWPHDEGPQGRHS-SKEHRH
HGDYGRHSVGPSSSRHQGE-------------------EPSRRGSKPHPRDSGRHEGRPH
SQPSSQKKAQQADLR-----GQPSYP-------SSQSEYSQPSRQSVAYHHPSEPKKAQR
---PMQSGPLA----QPSKAEPLAHRRLLL----NMGPQRQAVWMRERHLAGRQGRLKAE
QLDSSKPPAKVQQP-QQQQQQ--PGRAQP-----QGATAAGVHLES------RVGRDH--
---KQTRLPLQKVAQGRNPKVLSGSFTWSSYS--MSSSPHL-------------------
--VRFGN----TEPFVRV--------------VPNIRGASPS--QG-GKRERGAKVGAKP
GGVPLASGAPTGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
-----------TGDGYSRLTSM-------------VSHHF--------------------
--QCHFSTSRRLDPKEPLGNQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPDQERS-RGPG----GP-------------------------QPGSRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPAG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFNDASK
EAGPKPLGSGPGPG------PAP--GAKTEPG----AR----------------------
------------M---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-ICPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP
LST----------------------------KASPQAKPLRASEPSKTPS---------S
VQEKKTRVPTKAEPMPKPPPETTPTP---AT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEVEDLVG
KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPS-E-RSKPLSS---GTGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDASLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQEAGARGPHGGP-SQPTGP----RGLGSFEYQDTTDREYG-Q
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSS-ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKM--G----PRATAEFSTQTPSPAPASDM
PRSAGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRV----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTTVQPLVINLNAQ--EHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRTGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PVGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QPQH
GPGL-----SAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPEMPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGLGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRS-GIKKRHSMPRLRDA
CEPESGT-EPCVVRRIADSSVQTDDEDGESRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIITPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQFVDFPATAA---A--P---------ATPSGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGASYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-GYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLESLGPG-SSGRPGKE-PGEPGVLDGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASTHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLGPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSSRDAVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRVRPPMRSQTSEEESPVSPLGRPR----PAGGP-LPPGGDACPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHR-
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRASSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQIPSGAQQQ----
-Q------------QQQQQQQQGLGLQP----PQQALTQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPSTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGD---------GPLPPGGSGPGPGPGAGKPPSAPA----G
GGQLPAA-------GAARAVGVP---PVPG----PGPGPG--------------------
--PGPGSISRRLDTKEPSGSQRAASPTPNQAS---ATAPGRESPREMR-AQGPSGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRSSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQDRS-QGPV----GP-------------------------QPGPRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPL-PSKPSTAEPRPPAGEALAKSATAVPSG
VGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQPAPSKGPPKIVFSDASK
EAGPRPPGSGPRPG------PAP--GAKTEPG----AR----------------------
------------TGLG----SGPGALPKTGGTISPKHG-----RAEHQAASKA-TAKPKT
MPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGGLGEPTPMPLPTSQ-QSPAGAPHRAAGTAPLKQKDPQGMGQPSGPLPAKAS-
--------------------PLPTKASPLPTKGSPQAKPLKASEPSKTPS---------S
AQEKKTGVPAKAEPMPKPPPEATPPP---GT--PKVKSGGKKSEPATPVVK-AVP-EAP-
--------------------------------------------------KGGESEELVG
KPYSQDVSRSPQSLSDTGYSSDGVSSSQSEITGVV-QHEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMQPLLEAPILAPSGE-RSKPPCS---STGEEQTRRPHSLSVTPEAFDSEEELED
ILEE-EEDSLNWGRRKEQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPG-
-ALPKRRLPHNATTGYEELLSEEGPAEATG-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PTPSLDSEAEALD-SGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSVRPLKSAEE
AYEEMMRKAELLQ-RQQGQVAGARGPPGGP-SQPTGP----QGQGSFEYQGAPDADYG-R
TAQPASEGTPAS--LEAAVYEEILQTSQSIVRMRQASSRDLAFAEEKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTC--TSSDSSGGRVIPDVRVTQ-HF
AKDPQEP-LKLHSSPVSPSP-ASKEVGTSFSHGPGTP-ATTAVAPGPAGLPRGYMTPTSP
AGSERSPSPSSTGHSYGQTPTTANYGSQTEELPKAPCGPAAGGRAAREKPLSGSDSEGAT
PQPSRAYSYFAGSSPPLSPSSPSESPTFSLGKL--G----PRATAEFSTQTPSPTPASDM
PRSPGASTPTPMVAQGTQTPHRPSTPRLVWQQSSQEPPFMVITLASDASSQTRMVHASAS
TSPLCSPTDTQP--TTHSYSQTTPPSVSQLPPEPPGP-SGFPRV----------------
--PSAGADGALALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAGKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTTPYRGGPRG--
----------RPREAKFARYNLPNQVVPLARRDVLITQMGTTQSVGLKPG-PVPEPAAEA
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PVGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAHSMPEKSMADA--ASPGQVSGPFYGPRDPEPPEPPTY
RAQGVVGPGPLEEQRPYLQGLPGRLYSSMSDTNLAEAGLNYHAHRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGHYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGQ
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--SGPDLVQY-QPQH
RPGI-----SAPQGLAPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGPYRYHTPSRFPVASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPELPAGAAREESLSTTTPA-AVKEAAGAPAP--------SPLTAQKPPG
DA-APGGGSGALSRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQ-KPFPAAC-EAPSRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AVAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAVRS-GIKKRHSMPRLRDA
CEPESGP-EPCVIRRIADSSVQTDDEDGESRYFLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAIASSST--------ATATARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVVGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-PQQLYAASLLQRGLVGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESMAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPSGQYVDFPATAA---A--A---------VTPSGPAVFQQPRFP
PPAPQYTA-GSGGPTQNGFPAHQ----PPTYPGPSTYPA-PAFPPGTSYPAEPGLPNQSA
FHPTG-------HYAAQTPMPTTQSTLFPVPADSRAPHQKPRQTSLADLEQKVPTNYEVI
TSPVVAMSSAPSETSYSGPAV-SS-SYEQGKAPELPRASDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTVPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGSTL
PCCYGRGEEESEEDSYDPRGKVGH-----HRSMESNGRP--------ASAHYYSDSDYRH
GARAEKYGLGPVGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSTRDTVEEDDRMYGGSSR-S
RVSSVYSGEKLPSHDFSGRGKGYERE------------------REAVERLQKVGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKRE-EYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----SRHTGE-------------------EPGRRAAKPHVRDVGRHDARPH
PQPSPAPAMPKK--------GQPGY--------PSSAEYSQPSRVSSAYHHASDSKKGS-
RQVHSGPAAL------QPKPEPQAQPQL-QGRQAAPGPQQPQPPSSRQMPSGAASRQPQ-
--------------T--QQQQQGLGLQP----PQQALSQARLQQQS--------------
QPTTRGPAPSASQQPVGKPQ-PGPTTAAGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGMKT---G
ARPGGPAGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGSSGP------GP--GPGAGKPPSALA----G
GGQLPAAGAA-------R-AGPPAPGLGLGPGPGPGPG----------------------
--PGPGPGPGRLDPKEPLGSQRTTSPTPKQAS---ATAPGRESPRETR-AQGPSGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----AT-------------------------QSGPHQAE--------
---TARATSVPAP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPVGEAQGKSATTVPSG
LGAGEQP-QEGLTGKLFGLGASLLTQASTLISV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRLPGSGPGPE------PTS--GAKTEPG----AR----------------------
------------TGPG----SGPGALAKTGGTASPKHG-----RAEHQVAASKAAAKPKT
TPKERA-TCPLCQAEL-NVGSRGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPM-PLPTSQQPPAGVPHRAAGAAPLKPKGPQGLGQPSGSLPAKASP
QAAKASPQAA-------K-------ASPQAAKASPQAKPLRASEPSKTSS---------S
AQEKKTGIPVKAEPVPKPPPETTVPP---GT--PKAKSVVKRTEPATPVTK-PVP-EAP-
--------------------------------------------------KGGEAEESAS
KPYTQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQDVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQAVAPSAE-WGKPPRS---SAVEDQKRRPHSLSIMPEAFDSEEELGD
ILEE-EDDSLAWGHQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPART--EM
TDEEFMRRQILEMSAEEDNLEED-DTAV---PGRGLAKHSTQKGSA--RPRPESSQES--
----ARRLPHNATTGYEELLSEGGPAEPTD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEQSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEEMREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPPRLYKSGSEYNLPAFMSLYSPTEDPSGSSTTPSSGRPLKSAEE
AYEDMMRKAELLQ-RQQGQVAGARGAHGGP-SQPAGS----RAQGSFDYQDTQDRDYG-R
ASQPAAEGTPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
YLNAESTYMDPMKQNGGPLTPGTSPTQLAAPVSFAPAT--SSDSGGGRVIPDVRVTQ-HF
AKEPQDS-LKLHSSPVSPSL-ASKEVGMTFSQGPGTP-ATTVIAP-------WYMAPTSS
AGSERSPSPSSAVHSYGQTPTTANYGSQTEELPQAPSGPTVGGRAPREK---GTDAEVGA
PQASRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----TRATAEFSTQTPSLTPSSDI
PRSPGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASAS
TSPLCSPTDTQP--TSHSYSQTTPPSASQMPSEPGGP-PGFPRA----------------
--PSAGADGPLALYGWGSLPPENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPMP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPRESKFSRYNLPNQVAPLARRDILITQMGTAQSVSLKPG-PVPEPGGEP
HRAVPAELRSHA---LPGVRKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVADA--ALPGQSSGPFYSPRDPEAPEPLTF
RAQGVVGPGSHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRLGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GGGPDLVQY-QPQH
GPGL-----NAPQGLAPLRSGLLGNPTFPEGQASPGNLAQYGPAASQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPIASSIPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEPPAGAAREEPLSTTAP-AVIKEAPAAPAP--------APPPGQKPSG
DAAAAGGGSGVLSRPGVEKEEASQEDGQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AMAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDV
CEPESGP-EPCTVRRIADSSVQTDDEEGEGRYFLTR-RRRTRRSADCSVQTDDEDNADWE
QPVRRRRSRLSRHSDSGSDSKHDATASS--A-------AATAARATSSIGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKPFMADSTLRQQTLPRPV
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYTA-GSTGPTQNGFPAHQ----ASTYTGPSTYPA-PTFPAGTSYPAEPGLPSQQA
FHPTG-------HYAAPTPMPTTQSTPFPVQADSRALHQKPRQTSLADLEQKAPTNYEVI
TSPAVTMSSGPSEASYSGPAV-SS-SYEQGKAPEHLRGSDRSSVSQSPAPTYPSDSHYTS
LEQSVPRNYVMIDDISELTKDSTPTAADSQQLEPLGPSGVSGRPGKE-PGEPAVFEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----YRSMESNGRP--------ASTHYYSDSDYRH
GARAEKYGPGPMGSKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPT--PTVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSR-S
RGASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDAGRHETRPH
PQASPAPAMQKK--------GQPGY--------PGSADYSQSSRTPSAYHHASDSKKGS-
RQAHAGPTAL------QPKPEPQSQPQM-QGRQAAPGPQQSQSPSSRQMASASRQ----P
Q-QQQQQQQQQ--QQQQQQQQQGVGQQA----PQQAPSQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPSTAPGPQP--------AGL-----------------
----PRTEQASSSK-AAA--------------KAPQQGRAPQAQPAPGPGPTGVKP---G
ARPGGTPGGPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SVSRRLDPKEPLGSQRTASPIPKQAS---ATAAGRESPQETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYFVPQIAPLPSSTLCPICKTSDLTSSPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQEKS-RGPG----GP-------------------------QPGPRQAE--------
---TARASSVPGP-IQAAAPPEVGRVPPQPPL-PIKPSTSETRPPAGEAMAKSATTVPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQGQSAPSKGPPKIVFSDASK
EAGPRPPGSGSGPG------SAP--GAKTEPG----AR----------------------
------------TGPG----PGPGAPARTGGTTSPKHG-----RAEHQA-VSKATAKPKT
MPKERA-ICPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-PLPTSQQPPVGAPHRTAGTAPLKQKGPQGLGQPSGSLPAKTSP
----------------------------MPTKASPQAKPLRASEPSRTPS---------S
AQEKKTGVPAKAEPVPKPPPETSLPP---GT--PKAKTGARRTEPAT---S-ALP-EAP-
--------------------------------------------------RGGEAEELGG
KAYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEMEQLDSAGVTGPRPPSPSELH
KPH--STRPSLEAQGPAPSGE-RSKPPCS---SSGEEQKRRPHSLSIMPETFDSDEELED
ILEE-EEDSLKWGRQSEQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DAAT---SGHSMAKHGTQKGGP--RPKPEPSQEPI-
-ALPKRRLPHNATTGYEELLSEGGPAEATD-GTGALQGGLRRFKTIELNSTGSYGHELDL
GPGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEAPD-GGPTRLYKSGSEYNLPTFMSLYSPTETPLGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPHGGL-SQPIGP----RGQGSFEYQDTPDHDYG-R
AAQPASEDTPAG--LGAAVYEEILQTSQSIARMHQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTSTSSSSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEIGISFSQGPGTP-ATTAVAPCPAGLPRGYMTPTSP
AGSERSPSPSSTGHSYGQSPTTANYGSQTEELPQAPSSPTASGQAAREKPLSVSDGESSA
PQPARGYSYFVGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPASDM
PRSPGAPTPTPMVAQGTQTPHRPSMPRLVWQQSSQEAPFTVVTLASDASSHTRMVHASAS
TSPVCSPTDTQP--TTHSYSQTMPPSVSQLTPEPPGP-PSFPRA----------------
--PSAGADGSLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAPQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITHMGTAQSVGLKSG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSASEKSVADV--APPGQSSGPFYSPRDPEPPEAPTY
RAQ--VGPGPHEEQRPYPQGLPGRLYASMSDTNLAEAGLNYHAHRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAVFQEASLAQYSATTAREISRMCAALNSMD-HYGGRHGSG-G-SGPDLMQY-QPQA
GPGL-----SAQQGLTPLRPGLLGNPTFPEGHPSPGNLAHYRPTAGQG-TTVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPPPSRFPTASSIPPAEGPVYLGKPVA-KAPGAGGPL-------
----------R---PAGAAREEPLSTATPA-AIKEAVA------------APMAGQKPPV
DAA-PGGSSGALSRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EVPGRGPPPA--------ATELAQNGQYWPPLTNT
AFI-AVAGPEGPGQPR-EPMMHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPEAGP-EPSGARRIADSSVQTDDEDGEGRYLLTR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------TTTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQI
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQGHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGY----A------APAGQYADFPVTA----A-AP---------ATPSGPTALQQPQFP
PPAPQYTA-GSSGPTQNGFPAHQ----APTYPGPSPYPA-PAFPPGASYPAEPGLPSQQA
FHPTG-------HYAAQTAMPTTQSTLFPVSADSRTPPQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-SYEQSKAPELSRASDRSSVSLSPAPTYPSDSNYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPMGPS-SSGRPGKE-PGEPGVLEGPTL
SCCYARGEEESEEDSYDPRGKSSH-----HRSVESNGRP--------ASTHYYSDSDYRH
GARAEKYSPGPMGPKHPSKSLAPAAVSSKRSKHRKQAMEQKISKFSPIEEAKDVESDLAS
YPT--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSGRDPVEEDDRMYGGSSR-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------RE--ERLQKAGPKPSS
LSMAHGRVRPPIQSQASEEDSPVSPLGRPR----PTGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGSARHSYHDYD-EPPEEGLWPHDEGGSGRHASAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHVRDLGRHEARPH
PQPSPSTVVQKK--------GQPGY--------PSPAEYSQPSRTPSAYHHASDSKKGS-
RQAHSGPAAL------QPKPEPQPQPQP-QGRQAAPGPQQSQPPPSRQMPSVTASRQLQT
QQ-----------------QQQGLGLQP----PQQASSQARLQQQG--------------
QPTARGSAPAA-SQPSGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQANGSK-GTT--------------KAPQQGRPPQAQPPPGPGPAGLKA---G
ARPGGTPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SVSRRLDPKEPPGSQRAASPTPKQAS---ATAPGRESPRETR-AQGPAGQEADG
PR RTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLP SSTLCPICKTSDLTSTPSQ
PNFNTCTQCRNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRA LGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAQSPAKQPL
GKPEQERL-QGPG----AP-------------------------QPGPRQAE--------
---TARATSVPGP-AQAAAPPEVGRASPQLPP-PVKPSTAEPRPPAGEALAKSATAVPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEAEPQGQAAPSKGTPKIVFSDASK
EAGPR PPSSGPGPG------PAP--GAKTEPG----AR----------------------
------------TGPG----LGPGALARTGGTTSPKHG-----RAEHQA-ATKATAKPKT
MPK ERA-TCPLCQAEL-NVGSKGPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-PLPASQQPPSGAPLRATGAAPPKQKGPQGPGQPSGPLPAKASP
----------------------------LPTKASPQAKPLRASEPSKTPS---------S
AQEKKPGIPAKAEPGPKPPPEATLPP---GT--PKGKTGARRTEPATPVVK-AFP-EAP-
--------------------------------------------------KGGESEELAG
KPYSQDLSRSPQSLSDTGYSSDGVSSSHSEITGVV-HQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQGPAPRSE-QSKPPR----SSGVEQKRRPHSLSIMPEAYDSDEELED
ILEE-GEDSLEWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEEE-DATP---VGPGLAKHGAQKGGP--RPRPEPSQDPA-
-ALPKRRLPHNATTGYEELLSEGGPAEASE-ATGALQGGLRRFKTIELNSTGSYGHELDM
GQGPDPSLEREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPTRLYKSGSEYNLPTFMSLYSPTETPSGSSAAPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQGVG------GP-SQPTGP----RSQGTFEYQDAPDQDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLDADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--PSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSAASPSS-ASKEVGVSFSQGPGTP-ATTAVAPCPAGLSRGYMTPTSP
GGSERSPSPSSVGYSYGQSPATANYGSQTEELPQAPSGPTASGRAARDKPLSVSDGESGP
HKASQGYSYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPALDM
PRSPGAPTPAPMVAQGTQTPHRPSTPRLVWQQSSQE-AFMVITLASEASSQTRMVHASAS
TSPVCSPTDTQP--TTHSYSQTTPPSASQLPPEPPGP-HGFPRA----------------
--PSAGAEGPLAVYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGWQSTAVQPLVINLNAQEQTHAFLSTSTTMSI
TMASSVLLAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGLKSG-PVPEPGAEP
HRAAPADLRSHA---MPGARKPHTVVVQMGEGAAGTVTTLLPEE-PTGALDLTGMRPESQ
MACCDMVYKLPFGSSCTGTFHPTPSAPEKNVADI--APPGQGGGPFYSPRDSEPPEPPAY
RAQGVAGPGPHEEQRPYPQGLHGRLYSSMSDTNLAEAGLNYHAHRTGQLFQGPGRDSAVD
LSSLKHSYSLGFVDGRYLGQGLQYGSYTDLRHPTDVLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYAGRHGGG-G-GGPDLMQY-QPQP
GPGL-----GAPQGLAPLRPGLLGNPTFPEGHPSPGNLAQYRPTVGPG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRR-GMYRPYVSGGVTAVPLTSLTRM
PVIAPRIPLGPTGLYRYPAPSRFPTASSVPPAEGPVYLGKPAAAKAAGVGGPP-------
----------RPELPAGAAREEPLSTATPA-AAKEVLAAP--------APAPLAGQKPPV
DAA-PGGGSGALSRPGLEKEDAVQEERQRQQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPPA--------APELAQNGQYWPPLSHT
AFI-AVAGPEGPGQPR-EPGLHRGLPSSASDMSLQTEEPWEVGRG-GIKKRHSMPRLRDA
CEPESGP-EPCGVRRIADSSVQTDDEEGEGRYLLTR-RRRVRRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAAASSSPAAAAPPPPAAAAARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITTVTDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAQLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQHGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-VGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYADFPVTA----A-AP---------ATPSGPTAFQQPRFP
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGTSYPAEPGLPGQQA
FRPTG-------HYAAQTPMPTTQSTLFPVPADSRAPHQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-SYEQGKAAELPRASDRSSVSLSSASTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPESQRLEPLGPS-SSGRPGKE-PGEPGILEGPVL
PCCYTRGEEESEEDSYDPRGKSGH-----HRSMESNGRP--------TSAHYYSDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSGRDPVDEDDRTYGGSSR-S
RVASAYGGEKLSGHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRARPPMRSQTSEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWLHDEGGPSRHASAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHTRDLGRHEARPH
PQPSPAPAMQKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKSS-
RQAHAGPTTP------QPKPEP--QPQP-QGRQAAPGPQQSQTPPSRQTPSATASRQPQT
QQQQ-------------QQQQPGLGMQP----PQAAPAQARLQQQG--------------
QPAARGPAPAA-SQPAGKAQ-PGPTTATGPQP--------AGP-----------------
----PRAEQANGSK-GTA--------------KAPQQGRPPQAQPPPGPGPAGMKA---G
ARPGGTPGAPAGQPGTDGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MSV-QPDAEPQGQPAPSKGPPKIVFSDASK
EASPKPPGSGPGPG------PAP--GAKTEPG----AR----------------------
------------TGPG----SGPGGVARTAGTPSPKHG-----KTEPQA-VSKAAAKPKT
MPKERA-SCPLCQAEL-TLGGKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPP-ASPQPPAGAP-RASGTAPLKQKGPPGLGQPSSPQPAKASP
QPAKASPQPA--------------KASPQPAKASPQAKPLRAAELSRTPS---------G
AQEKKAGAPAKAEPTSKPPPETTPPP---GP--PKAKSGARRTEPAPPVSK-AVP-EAP-
--------------------------------------------------KGGEAEELAG
KPYPQDLSRSPQSLSDTGYSSDGISSSQSEITGTV-QQEGEQLDSAGVAGPRPPSPAELR
KVGG-GQRPLLEAQGLVPRGE-RG--------SGGDEQKRRPRSLSIMPEAFDSDEELED
ILEE-EEHALEWGRQREPRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEEEDEAAP---ARPGLTKSSPQKGTG--WPRPEPGQEPV-
-ALPKRRLPHNATTGYEELLPEGGPAEAPD-AGGALQGGLRRFKTIELNSTGSYGPELDL
GAGPDPGLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGASPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPGRLYKSGSEYNLPTFMSLYSPTEAPSGG--TPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQ-----------SP-SQPPGP----RGQGPPDYQDTADPGYG-R
AAQPA------E--GTQAVYEEILQTSQSIARMRQASSRDLALAEDKR--------KEKQ
FLNAESAYLDPMKQNGGPLTPGTSPTQLAAPVSFSPST--TSDSSGARVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPGS-APQQVAAPFSRGPGVP-ATPAAAPGPAGLPHGYMAPASP
AGTEHSPSPSSVGRGYGHSPTTANYASQTEELPQTP-----GVRAAREKALGTGDGESSA
PQPARGYSYFVGSSPPLSPSSPSESPVFSPGKR--G----PRATAEFSTQTPI--PVSDV
LRSPGVPTPTPTVAQGTQTPHRPSTPRLAWQQPPREAPFMVITLASDAASQTQMVHASAS
TSPVCSPTDTQP--TAHSYSQIAPPAA---PPEPPGP-PGFPRA----------------
--PGAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAMEARKYGLALDPMPGRQSTAVQPLVINLNAQEQSHAFLGSATTVSI
TVASSVLVAQPKQPVVYGDPFQSRLDFGQGTGSPICLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARREVLITQMGTAQSAGLKPG-PGLEPGAEP
HRATPAELRAHA---LPGARKPHTVVVQVGEGPAGAVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVADA--APPRQSGGPFYGPRNPELPEPPAY
RAQGLVGPGPHEEQRPYLPGPPGRLYSSMSDTNLAEAGLSYHAHRIGQLLQGPGRDSAVD
LSSLKHSYSLGFTDGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDPRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-HYGGRRGS----GGPDLLQY-QPPP
GPGL-----SGPQGLAPLRPGLLGNPTFPDGHPGPGNLAQYGPAAGQG-AAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYATGGVPAVPLASLPRL
PAIAPRVPLGPPGLFRYPAPSRFPTAPSIPPAEGPVYLGKPAAAKVPGAGGPA-------
----------RPELPAGAAREDSLSTATPA-AIKEAVAA------------PGASQKPPG
DV-APGAGSGAPGRPGPEKEDASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRHKAPFPAAG-EAPGRGPPAA--------ATELAQNGQYWPPLTHA
AFI-AVAGPEGPGQPR-EPAPHRGLPSSTSDLSLQTEEPWEAGRG-GLKKRHSMPRLRDA
CEPEPGP-KPCTARRLADSSVQTDDEDGEGRYFLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDAAASSSATAA-----AATTAKATSSVGIQTTSDCSVQ
TEPDQLPRVSPAIRITAAADPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQAVAAPQL
VGPAALAPYLPSIQLVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVGPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLMGPAAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPAAAA---A-AP---------ATPSGPAAFQQPRFL
PPAPQYAA-GSGAPTQNGFPAHQAPHQAPSYPGPSAYPA-PAFPPGTTYPAEPGLSGQPA
FRPTG-------HYAAQAPMPATQSTLFPGPADSHAPHQKPRQTSLADLEQKVPTNYEVI
ASPGVAMSSAPSETSCSGPTV-SS-SYEQSKSPEQPRASDRSSVSQSAVPTYSSDAHYAS
LEQNVPRNYVMIDDISELTKDSPSTAPESQRLEPLGPG-SGGRPGKE-PGEPGLLEGPTM
PCCYARGEEESEEDAYDPRGKGGH-----HRSMEGNGRP--------ASTHYYGDSDYRH
GPRAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAAGGSLASRGRKFQDEITYGLRKNVYEQQRHYGVAGRDPADEEDRGNGGSGR-A
RAAVAYRGEKLSSHDFGGRGKGYERE------------------REAAERLPRAGPKPSS
LSMAHGRARPPVRSQASEEESPVSPLGRPR----PAGGA-LPA-GDTCPQFCSS-HSMPD
VQEHV-KEGPRAHTYKREEGYILDDPHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSSS--SSQKRGPARHSYHDYD-EPPEEGMWPHDEGGPGRHAAAKEHRH
HSDHGRHS-----GRHAGE-------------------DPGRRATKPHVRDPGRHEGRSQ
PQLSPAPAAQKK--------GPPGY--------PSPAEYAQQPRVPSAYHHAPDSKKGS-
RQAHAGPPAP------QPKPEPQPQPQP-PGRQPPPGPQQSQPPLSRQPPSAAAPRQPQP
PQQ----------------QQPSLGPQH----PQQAPPQGRLQPQS--------------
QPAARGLAPAT-SQQAGKPQ-PGPAMATGPPP--------AGA-----------------
----PRAEQANGSK-GTA--------------KAPQQGRPPQAQPPPGPGPAGTKA---G
ARPAGTPGAPAGQPGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-----------MGNEASLEGGAGDGPLPPG--G--------VGPSAGKPPSAPAGGGQLP
AAALTRPTAG-------QPG----PGPGTG--PGPGPGPG--------------------
--QGPDSVSRRLDPKEPLGSQRAASPTLKQTS---ATAPGRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPERG-TPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEKEQS-RGPG----SP-------------------------QLGSRQAE--------
---TSRATSVPGP-AQAAAPPEVGKVSPQPSF-PTKPSTAESRPSSGEATVKSATTLPAG
LGASEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPETDPQGHSSPSKGPPKIVFSDASK
EAGPRPPSSGP--G------PAP--GAKTEPG----AR----------------------
------------TGPG----SGPGTPAKTGGTTSPKHG-----KAEHQA-APKAMAKPKT
TPKEKA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEQTPL-PLPTSQHPPTGAPHHAAGAAPLKQKGAQGLVQPSGPLPA----
-------------------SPLPTKASSQPTKASPQAKTFKASESSKTTS---------S
AQEKKTGVPAKAEPIPKPPPETTLPP---GT--PKVKSGIRRIERASPAVK-AVP-EAA-
--------------------------------------------------KSGETEEPLG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPLLETQAAAPSVE-RSKPPCS---MTSEEQKRRPHSLSIMPEAFDSDEELED
ILEE-DEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPLRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAA---SGRGLVKHGTQKGGT--RPRPEPGQEPAS
--LPKRRLPHNATTGYEELLSEGGPAEPTD-SGGTLQGGLRRFKTIELNSSGSYSHELDL
SQGSDASLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTEMPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQGVGVHGPHSGP-SQPTGP----RSQASFEYQKASDHEYG-R
AAQSAPEGTAAS--LGTAVYEEILQTSQSIARMRQASSQDMAFPEDKK--------QEKQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFTTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPTFPGS-ASKEVGTSFSQGPGTP-ATTAVAPGPASLPQGYMTPTSP
AGSEHTPSPSSTTYSYGQSPTTANYGSQTEELPEASSGPAAGSRAAREKALGGTDGEAGP
PHASREYSYFAEPSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPSLEM
PRSPGTPTSTSMVAQGTQTPHRPSTPRLVWQQTSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--TTHSYSQTTPPSGSQLPPE----PPGFPRA----------------
--PNAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASTVLMTQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVRQVEQAVQTAPYRGGSRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTTQSVSLKSG-PVSEPSAEP
HRAIPTELRSHA---LPGARKPHAVLVQMGEGTAGTVTTLLPEE-PTSALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVADP--ALPGQSSGPFYSSRDPEPSEPPTY
RAQGVVGPAPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRLGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPIRRYSSVSNIYSDHRYGP
RGEAGGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--GTGSDLVQY-QPQH
GPGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPRSLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GIYRPYMSGGATAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPISSSVPPAEGPVYLGKPA-AKAPGVGGTP-------
----------RPELPAGAAREEPHSTAAPA-A-KESATAPAP------A--PPPGQKPPG
DGAAGGGGSVVPGRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAVC-EAPGRGPTPA--------APEVAQNGQYWPPLTHT
AFL-AVAGPEGSGQSR-EPILQRGLPSSASDLSLQTEEPWEATRS-GIKKRHSMPRLRDA
CEPESAP-EPYVVRRIADSSVQTDDEDGEGRYLLTR-RRRTRRSTDCSVQTDDEDNAEWE
QPVRRRRSRVSRHSDSGSDSKHDATASSSTA--------ATTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGSL----------GRFEKKKPDPLEIGYQAHLPLESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTTDSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRECSPLRSLGAHRDYLSDSELNQLR
LQGC----T------TPAGQYSGFPATA----A-AP---------ATPSAPTAFQQPRFS
PPAPQYTA-GNIGPTQNELLAHQ----APTYPGPSTYPA-PAFPASTTYPAEPGLPNQQA
FCPSG-------HYTAQTPMPTTQSTLLPIPADSRAPHQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-SYEQGRTPELPRASDRGSVSQSPVPTYPSDSHYTS
LEQNVPRNYVMINDISELTKDS--TVPDSQRMESLGPG-SSGRSGKE-SGEPGALEGPTL
PCCYARGEEESEEDSYDSRGKPSH----HHRSVESNGRP--------ASTHYYSDSDYRH
GTRGEKYGPGLMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDDRMYGGSSR-S
RVGSAYSGEKLSSHDYSGRGKGYERE------------------REAVERLQKAGSKPSS
LSMTHGRMRPPMRSQASEEESPVSPMGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHI-KDGPRAHLYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHTVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEVGPGRHGPAKEHRH
HSEHGRHA-----GRHAGE-------------------EPGRRAAKSHVRDPGRHEARPH
AQPSSASAMLKK--------GQPGY--------PSPTDYSQPSRAPAAYHHTSDSKKGS-
RQAHSGPAAL------QPKPEPQALPQL-QGRQAAPGPQQSQPPSSRQMASGAALRQPQI
QQQQQQQQQQQQQPQQQQQQQPGLGQQP----PQQASSQARPQQQS--------------
QATARGPATAA-SQPAGKPQ-PGSTTATGPQP--------AGL-----------------
----PRAEQADGSK-VTT--------------KTPQQGRAPQAQPTPGPGPT--------
ARPGGPPGAAPGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSRQGE--------
---TARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPGPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------TGPTGPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
LPTKAS--------------PLSTKASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMSKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-PLPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTADHDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPIGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--R----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADT--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAVREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESAA-EPCMVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQARFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPTDSRAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGSAV-SS-GYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHPGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
QQQQ-----------QQQQQQQGLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRGPQAQPTPGPGPAGVKA---G
ARPGGTPGAPTSQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

----MQMYLLRIQSMLSMVLGP-------G--Y-----------AARSKPDTSSCGAPI-
-KQLFEKRNG-------RA------QIAVL--PTPLHLNC--------------------
--APLESISRRLDPKEPLGSQRTASPTPKQAS---ATAPARESPRETR-AQGPAGQEADG
PHRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQEPS-RVPG----GP-------------------------QLGSRQAD--------
---TSRATPVPRP-AQAAAPPEVGKVSPQPSV-PTKPSTAEPRLPTGEAPAKSATTVPSG
LSASEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQGQPSPSKGPPKIVFSDARK
EAGPRPPTSRP--G------PIP--GTKTEPE----AR----------------------
------------MGPG----SGPGTLAKTGGITSPKHG-----KAEHQA-VSKTAAKPKT
TPKEKA-SCPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEQTPL-PLPTSQQPPIGAPHHAAGSAPLKQKGPQGLGQPSSPLPTKASP
---------------------LPPKPTPFPNKASPQAKPFKAPESSKIPS---------S
AHEKKTGIPAKAEPIPKPPPETTLPP---GT--PKVKSGVRRIERASPVVK-AVP-EAS-
--------------------------------------------------KSGDAEEPVG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-GVRPLLEAQPAASSAE-QSKPPCS---GTGEEQKRRPHSLSIMPEAFDSDEELED
ILEE-DEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPLRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAV---SGCGLAKY-----ST--RPRPESSQEP--
----ARRLPHNATTGYEELLSEEGPTESTD-SGGALQGGLRRFKTIELNSSGSYSHELDL
GQGPDASLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTEMPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVVGAHGSPGGP-SQPIGP----RGQGTFEYRDAPDRDYG-R
AAQPAPEGTAAS--LGTAVYEEILQTSQSIARMRQASSQDLAFPEDKK--------KERQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFTTST--SSDSSGGRVIPDVHVTQ-HF
AKEPQDS-LKLHSSPSSPSS-ASKEVGTSVSQGPGTP-ATTAVAP-------WYIAPTSP
AGSERTPSPSSTAYSYGQSPTTANYGSQTDELPEASSGSAAGSWAAREKPLSRTDGEAGP
PHASWGYSYLAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPRPLSSLEM
PRSPGTPTCTSMVAQGTQTPHRPSTPCLVWQQTSQEAPFVVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--TTHSYSQTTPPSVSQLSSETPGP-PGFPRA----------------
--PSAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
VILTDQGMDLTSLAMEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYKSGSRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGATQSVSLKSG-PVSEPSAEP
HRAIPSELRSHA---VLGARKPHTVVVQMGEGTAGTVTTLLPEE-PASALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPNAPEKSVADT--SLPGQSSGPFYSPRDPELSEPPTY
QAQRVMGPGLHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGSGRDSAMD
LSSLKHSYSLGFADGRYIGQGLQYGSFTDLRHPTDHLTHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--STGPDLVQY-QPQH
EPGL-----SAPQGLAPLRPGLLGNPTFPEGHPGPRNLAQYGPAAGQG-TVVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGVATAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPISSSVPPSEGPVYLGKPA-AKAPGVGGQP-------
----------RPELQAGAAREEPHSTAAPA-AVKESVAAPAP------P----PGQKPPG
DA-AAGGGSVALGRPGLEKENASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPSRGPPPA--------APELAQNGQYWPPLTHT
TFL-AVAGPEGPGQPR-EPVLHRGLPSSASDLSLQTEEPWEAGRS-GIKKRHSMPRLRDV
CEPESAP-EPYVIKRIADSSVQTDDEDGEGRYLLTR-RRRTRRSTDCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------TTTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGHGESLACQTEPDGQ-AQGMAGPQL
VGPTAISPYLPGIQIITPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKVHVSPQKHFTTDSMLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EGHLPLAGQA-PPQLYAASLLQRGLVGPTTIPATKASLLRELDRDLRLVEHESTKLRKKQ
EELDEEEKEIDAKLKYLELGITQRKESLAKDR-GDRECSPLRGLGVHRDYLSDSELNQLR
LQGC----T------TPSGQYAGFPATA----V-AP---------ATPAAPTAFQQSRFL
PPAPQYTA-GNIGPAQNELPAHQ----APTYPGPNTYPA-PAFPPSTSYSAEPSLPNQQA
FCPSG-------HYAAQTPMPTTQSTLLPVPADSRAPHQKPRQTSLADLEQKVPTNYEVI
PSPVVAMSSAPSESSYSGPAV-SS-SYEQGKAPELPRASDRGSVSQSPVPTYTSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTVPDSQRLEPLGPG-ISGRPGKE-PGEPGVLEGATL
PCCYARGEEESEEDSYDFRGKAGH----HHRSMESNGRP--------ASTHYYSDSDYRH
GARVEKYGPGPVGPKHPSKSLAPAAISSKRSKHRKQGIEQKISKFSPIEEAKDVESDLAS
YPS--PAVSSSLASRSRKFQDEITYGLKKNVYEQQRYYGVSSRDVTEEDDRMYGGSSW-S
RVASAYSGEKLSSHDFSGRGKGYERE------------------REAVDRLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHSYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRLRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHGPAKEHRH
HSEHGRHA-----GRHAGE-------------------EPGRRTAKSHARDLGRHETRPH
PQPSPTPAMLKK--------GQPGY--------PGPTDYPQPSRAPAAHHHASDSKKGS-
RQAHSGPASL------QPKPEPQAPPQP-QSRQAAPGPPQSQPPPSRQMPSGASLRQPQM
QQQPS------PPPPQQQQQQPGLGQQP----PQQASSQARPQQQS--------------
QPTARGPASAA-GQPAGKPH-PGSTTAPGPQP--------VGP-----------------
----PRAEQADGSK-VTA--------------KTPQQGRVPQAQPTPGPGPAGTKP---G
ARPGGPPGTTPGQPGVDGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGSSGP------GP--GPGAGKPPSALA----G
GGQLSAAGAA-------R-AGPQAPGLGLGP----SPGPG--------------------
--PGPGSVSRRLDPKESLGSQRTTSPTPKQTS---ATAPGRESPRETR-AQGPSGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----AT-------------------------QSGPHQAE--------
---TARATSVPAP-TQATAPPEVGRVSPQPPF-STKPSTAEPRPPIGEAQGKSATTVPSG
LGAGEQP-QEGLTGKLFGLGASLLTQASTLISV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRPPGSGPRPG------PIP--GAKTEPG----AR----------------------
------------TGPG----SGPGALTKPGGVASPKHG-----RAEHQA-ASKAAAKPKT
TPKERA-TCPLCQAEL-NVGSRGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPM-PLPTSQQPPAGGPHQAAGAAPLKQKGPQGLGHPQA--------
--TKASPQAT-------K-------ASPQATKASPQAKPLRASEPSKTSS---------S
AQEKKTGVPVKAEPVPKPPPETTVPP---GT--PKAKSAVKRTEPATSVTK-PIP-EAP-
--------------------------------------------------KGGEAEEPIS
KPYTQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQDLEQLDSAGVPGPRPPSPSELR
KVGSSSLRPSLEGQAVAPSAE-WSKPPRS---SAVEDQKRRPHSLSIMPEAFDSDEELGD
VLEE-EDDSLAWGHQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--EM
TDEDFMRRQILEMSAEEDNLEED-DTAV---PRRGLAKHSAQKGSA--RPRTESSQESA-
-AVPKRRLPHNATTGYEELLSEEGPAEPTD-GSGALQGGLRRFKTIELNSTGGYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEEMREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPTRLYKSGSEYNLPAFMSLYSPTEAPSGSSSTPSSGRPLKSAEE
AYEDMMRKAELLQ-RQQGQVAGARGPHGGP-SQPTGS----RGQGAFEYQDAQDHDYG-R
ASQPAAEGTPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
YLNAESAFVDPMKQNGGPLTPGTSPTQLAAPVSFSAST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDS-LKLHSSPASPSL-ASKEVGMASSQGPGTP-ATTV------SLPRGYMAPASP
AGSERSPSPSSTVRSYGQTPTTANYGSQTEELPQAPSGPTASGRGPRER---GADAEAGA
PQASRGYSYFTGSSPPLSPSTPSESPTFSPSKL--G----SRATAEFSTQTPSLTPSSDV
PRSPGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQPRMVHASAS
TSPLCSPTDTQP--TSHSYSQTTPPSASQMPSEPAGP-PGFPRA----------------
--PSAGADGPLALYGWGALPPENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQGVQTAPYRGGPRG--
----------RPREAKFARYNLPNQAAPLARRDILITQMGTAQSVSLKPG-PVPEPGGEP
HRAAPTEIRSHA---LPGARKPHTVVVQMGEGPAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGGSCTGTFHPAPSAPDKSVADA--ALPGQSSGPFYSPRDPEPPEPLTF
RAQGVVGPGPHEEQRPYPQSLPGRLYSSMSDTNLAEAGLNYHAHRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSME-QYGGRHGTG--SGGADLVQY-QPQH
TPVL-----SAPQGLAPLRSGLLGNPTFPEGQPSPGNLAQYGPAASQG-AAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLARV
PMIAPRVPLGPAGLYRYPAPSRFPIASGVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPELPAGAAREETLPTTAP-AVIKEAPAAPAPA--------PPPGQKPPG
DAAAAGGGSGVLSRPGVEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPSRGPPPA--------AAELAQNGQYWPPLTHA
AFI-AVAGAEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDV
CEPESGP-DPCTVRRIADSSVQTDEEEGEGRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASS--A-------AATAARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFMTDSTLRQQPLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLSAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYPA-GSSGPTQNGFAAHQ----APTYTGPSTYPA-PTFPPGTSYPAEPGLPSQQG
FHPTG-------HYAAPTPMPTTQSTPFPVQADSRAPHQKPRQTSLADLEQKVPTNYEVI
TSPAVTMSSAPSETSYSGPAV-SS-GYEQGKAPEHLRGSDRSSVSQSPAPAYPSDSHYTS
LEQSVPRNYVMIDDISELTKDSTPTASDSQRLEPLGPSGVSGRPGKE-PGEPAVLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP--------ASTHYYSDSDYRY
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAA
YPT--PTVGSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDT-EEEDRMYGGSSR-S
RVASSYSGEKLSSHDFSSRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHSYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDMGRHETRPH
PQASPAPAMQKK--------GQPGY--------PGSADYSQSSRAPSAYHHASDSKKGS-
RQTHSGPAAP------QPKPEPQPQPQM-QGRQAAPGPQQSQSPSSRQMPPASRPPQTQQ
QQQQQ-QQQQQ--QQQQQQQQQGVGQQA----PQQAPSQARLQQQN--------------
QPSTRGSAPA--------------------------------------------------
----PRAEQASSSK-VAA--------------KAPQQGRAPQAQPAPGPGPTGVKP---G
ARPGGAPGGPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

-------MGNEASLEGGAGDGPL-PPGGAGPGP----GPGPGPSPGAGKPPSAPA----G
GGQLPAAGAARSTA--VPPVPGP----------GPG--PG--------------------
--PGPGSTSRRLDPKESLGSQRAASPTPKQAS---ATTPGQESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSHQGE--------
---IARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----TR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
LPTK---------------------ASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AIP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTADRDYG-R
AAQPVAEGTPAS--LGAAMYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASASL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPIGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPIPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAIGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAVREEPLPTTTPA-AIKEAAGAPAP--------APLAGRKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESAA-EPCMVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTSVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGSAV-SS-SYEQGKVPEVPRASERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RVPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
-----------------QQQQQSLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
-------------------SG---KCLNRLPVVNRQTKVF--------------------
--DNTLGISRRLDPKETLGSQRAASPTPRQAS---ATAPGRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQKSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPSHSPAKQPL
GKPEQERS-RGPG----GP-------------------------QPGPRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPL-STKPSTAEPRPPAGEALGKSATTVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSA-QPDPDAQSQPSPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PIP--GAKTEPG----AR----------------------
------------TGPG----SGPGALAKTGGTTSPKHG-----RGDHQA-APKAAAKPKT
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKSEWLCLNC
QTKRLLEGGLGEPTPL-PLPTSQQPPAGGPHRAAGAAPTKQKGPQGLGQPSGPLPAKASP
L----------------------------PSKASPQAKPLRASEPSKTPS---------S
AQEKKTGAPAKTEPVPKPPPETTVPP---GT--PKAKSGLRKTEPATPVAK-SVP-EAP-
--------------------------------------------------KGGEAEEPVG
KPYTQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPLLESQAVAPSGE-RSKPPG----STVEEQKRRPHSLSIMPEAYDSDEELGD
ILEE-EEDSLEWGRQREQRDTAESSDDFSSQLRHDYVEDSSEGGLSPLPPQPPARA--EL
ADEEFMRRQILEMSAEEDNLEED-DTAV---PGRGPAKP--KGGGS--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLSDGVPPEATE-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPGLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEAPDGGGPSRLYKSGSEYNLPTFMSLYSPTEAPSGSSPAPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGPAAGTQGPHGGP-SALAGP----RAQGTPGYQDAPDY---GR
APQPVPDGVPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTTA--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSF-ASKEVGVA-PQGPGTP-AVTAGAPCPASLPRGYMTPASP
AGSERSPSPSSIVHSYGQTPTTANYGSQTEELPQAPSGPVAGGRAIRERPVSGSDGDVGA
PQPSRAYSYFAGSSPPLSPSTPSEGPTFSPVKL--G----SRATAEFSTQTPSLTPASDM
PRSPSA----PTVAQGTQTPHRPSTPRLVWQQSSQEAPIMVITIASDASSQTRMVHASAS
TSPLCSPTDSQP--TSHSYSQTTPPSVSQLSSEPPGP-SGFPRA----------------
--PSAGTDGPLALYSWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLSQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVTPLARRDILITQMGTAQSVSLKPG-PVPEPGAEA
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PGSALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSAPEKSVADA--APLGQSSGPFYSPRDPEPPEPLTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRLGQLLQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGGG--GGAPDLMQY-QPQP
GPGL-----SAPQALAPLRPGLLGNPTFPEGQPSPGNLAQYGPAASQG-TTVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLASLTRV
PMIAPRVPLGPAGLYRYPAPSRFPIASSVPPAEGPVYLGKPATAKAPGAGGPP-------
----------RPEPPAGVAREEPLPTTAP-AAVKEAPVAPTPAP------GAPPGQKPPG
DAV-AGGGGGVLSRPGIEKEEGSQEERQRKQQEQLLQLERERVELEKLRQQRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKATFPAAC-EAPGRVPPPA--------AMELAQNGQYWPPLTHT
AFI-AVAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEHWEAGRG-GIKKRHSMPRLRDA
CEQESGP-EPCTVKRIADSSVQTDDEDGEGRYLMTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSSSDSKHDATASPSTAAAS----AAAAARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPAESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTTDSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEDSAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PSQLYAASLLQRGLQGSTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGREYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAAQYVDFPATA----A-VP---------ATPSAPTAYQQPRFP
PPAPQYTV-SSSGPTQNGFPAHQ----APTYAGPSTYPA-PAFPPGTSYPAEPALPNQQS
FQSTG-------HYAAQTPMPTTQSTLYPVQADSRAPYQKPRQTSLADLEQKVPTNYEVI
ASPGVTMSSASSETSYSGPAV-SS-SYEQGKAPEPPRSSDRSSVSHSPAPTYPADSHYTS
LEQNVPRNYVMIDDISELTKDSAPAAPDSQRLESLGPG-SSGRPGKE-PAEPGMHEGSTL
PCCYGRGEEESEEDSYDPRMKAGH-----HRSMEGNGRP--------ASSHYYSDSDYRH
GARAEKYGPGPVGPKHPSKSLAPAAISSKRSKHRKQGIEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGLSSREAAEEDDRMYGGSGR-S
RVSSAYSGEKLSSHEFSSRSKGYERE------------------REAVERLQKAGPKPSS
LSMTHGRARPPMRSQASEEESPVSPLGRPR----PAGGS-IPP-GDSCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDLGRHEARPH
PQSSPAPAMQKK--------GQPGY--------PSTAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAQ------QPKPDPQAQQQP-QGRQAAPGPQPSQPPPSRQMPSGAASRQPQM
QQQ--------------PQQQQGLGQQP----PHQVPSQARMQQQS--------------
QPTSRGPAPAA-SQPAGKPQ-AGPTTAPGPQA--------SAI----------------G
SVLQPRAEQANGSK-PTV--------------KAPQQGRTPQTQPTSGPGPAGVKT---G
ARPGGTPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------AQAGVQRHDLCSLQ-PLPPGS--SDS--------------PISASQ----E
AGI-TAASL--------K----------CV--SNS---HL--------------------
--QCHFSTSRRLDPKEPLGSQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPQ
GKPEQERS-RGPG----GP-------------------------QPGSSQAE--------
---TARATSGPGS-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFSDASK
ETGPKPSGSVPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALAKTGGTTSPKHG-----KAEHQVASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGELTPLPPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLAQPSGPLPAKASP
LPTK---------------------ASPLPTKASPQAKPLRASEPSKTPS---------S
ALEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVIK-AIP-EAP-
--------------------------------------------------KGGEVEDLVG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPCPPSPSEIH
KVGS-SMRPLLEAQGLAPSGE-RSKPPCS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-EEGSVEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGHGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-SSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAPGARGPHGGP-SQPIGP----RAPGSFEYQDTADHDYG-R
AAQPATEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSLDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEAGMPLSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTGHSYGHSPTTANYGSQTEDLPQVPSGLSTAGWAAREKPLSASDGEGGT
PQPSRAYSYFASSSSPVSPSSPSESLTFSPGKL--G----QRATAEFSTQTPSLAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSP-ETQP--TTHSYSQTTPPSVSQLPLEPPGL-PGFPRA----------------
--PSAGVDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTVPYRSGPRG--
----------RPREAKLARYNLPNQVTPLARRDILITQMGTAQSVSLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSAPEKSMADA--APPGQSSGPFYGPRDAEPPEPLTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QSQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNLAQYGPTAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPVASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEMPAGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGTGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWETSRS-GIKKRHSMPRLRDA
CEPESAP-EPCMVRRIADSSVQTDDEDGEGRYLLTR-RRRARRSTDCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSST--------AAATARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-M
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-APQLYAASLLQRGLTGPTAVPATKASMLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPSGQYVDFPATAA---A--P---------TTPSGPTAFQQPRFQ
PLAPQYTA-GSGGPAQNGFPAHQ----APSYPGPSTYPAAPAFPPGTSYPAEPGLPNQQA
FRPTG-------HYVGQTPMPTTQSTLFPVPADSRAPPQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPTV-SS-GYEQGKVPELPRAGDRGSVSQSPAPTYPSDSHYTN
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----HRSMESNGRP--------ASTHYYGDSDYRH
GARTEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRSRKFQDEITYGLKKNVYEQQRYYGMSSRDAVEEDDRIYGGSSR-S
RAPSTYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKVGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPSRHSYHDYD-EPPEEGLWPQDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRVAKPHARDLGRHEARPH
SQPSSAPVMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAP------QSKAEPQAQPQL-QGRQAAPGPQQSQPPSSRQIPSGATSRQPQM
QQQQ---------------QQQGLGLQP----PQQAPTQARLQQQS--------------
QPTTRGSAPVA-SQPAGKPQ-PGPTTATGPQP--------AGL-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPTSQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEVSLEGGAGDG-PLPPGGAGPGP--GP--GPGPGAGKPPSAPA----G
GGQLPAAG-------AARSTAVP---PVPG--PGPGPGPG--------------------
--PGPGSTSRRLDPKEPLGNQRAASPTPKQAS---ATTPGHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPDQERS-RGPG----GP-------------------------QPGSRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPAG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFNDASK
EAGPKPLGSGPGPG------PAP--GAKTEPG----AR----------------------
------------M---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-ICPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP
LSTKA---------------------SPLPSKASPQAKPLRASEPSKTPS---------S
VQEKKTRVPTKAEPMPKPPPETTPTP---AT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPS-E-RSKPLSS---GTGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEDFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTTDREYG-Q
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSS-ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKM--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRV----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQ--EHTFLATATTVSI
TMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSSPFYGPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QPQH
GPGL-----SAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPEMPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGLGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRS-GIKKRHSMPRLRDA
CELESGT-EPCVVRRIADSSVQTDDEDGESRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQFVDFPATAA---A--P---------ATPSGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGASYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI
ASPVVPMSSAPSETSYSGPAV-SS-GYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLDGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASTHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVE-DDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGWGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRVRPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHR-
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRASSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQIPSGAASRQPQT
QQ-----------------QQQGLGLQP----PQQALTQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPSTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPAPGPGPAGVKA---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

MPYQLALNSLASRWPSDGGSK-L-RIFSCQSDPGALRQKLPGQSPAQARPPH-------C
SQQVMPAFTPMTDS--LRC---------------ISNSHF--------------------
--QCHFSTSRRLDPKEPLGSQRAASPTPKQAS---ATTPGQESPQETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSRQGE--------
---MARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPRRASGASPLKQKGSQGLGQPSGPLPAKASP
---------------------LSTKASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGLAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTADRDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPTGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYIASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
QAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAVAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGTGGPP-------
----------RPEIPVGAVREEPLPTTTPA-AIKEAAGVPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESVA-EPCMVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSAFRQQTLPRPM
KTLQRSLSDPKPLSPTAEDSAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGSAV-SS-SYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDGDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
QPQQQQQQ-------QQQQQQQGLGLQP----P------------H--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------VSRRMDPKEPLGSQRAASAAQKPAS---ATAPGRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHSKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDM---TTA--------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLHSP---------ALSPAHSPAKPPL
GKTEQER------------------------GRGPGG------STPGARQAETA------
-----RATSVPGA-AHAAAPPEGGRVSPQPPH-PTKPSSAESRPPAGE------------
-ALAKSA-TXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX--XX-XXXXXXXXXX
XXX--XXXXXXXXX--------XXXXX---------------------------------
-----------XXXX-XX----XX---XXXXXXX-XXXX--XXXXXXXX-XXX-XXXXXX
---XXX-XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX----------------------XX-----XXXX---------
---------------------------X--XXXXXXXXXXXXXXX---------------
---------XXXXXX-X---XXXXXX-----XXXXXXXX-XXXXXXX---------XXX-
-------------------------------------------------XXXXXXXXXXX
XXXXXXXX-----XXXXXXXXXXX----XXXXXXX-XXXXXXXXXXXX----------XX
XXXX-XXXXXXXXXXX--------X--------XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXXREQRETGESSDIFGNQMRQ-YV-ESSEGSLSPVPPQPPERG-EMT
-VEEFMRRQILEMSAEEDNLEEEEAAPS----GHGLAKHGTQKGGP--RSRSEPSQEPV-
-ALPKRRLPHNATTGYEELLGEGGPAEAAD-GSGALQGGLRRFKTIELNSSGSYGHELDL
GQGPDPGLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
LSPSLDSEAEALE-GGPGRLYKSGSEYNLPTFMSLYSPTEISLGSAATSSTGGPLK-STE
AYEEMMKAELLRQQ-GQAAEGR-GLPTGPS-----QA-AAPRGQELFEPQDTA---QDSG
R-------AVQPAPDGTTVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KERQ
FLNAESACMDPMKQNGGPLTPGTSPTQLAAPVSFTSA---SSDSGGGRVIPDVRVTQ-HF
AKEPQDT-VRLHISPASPSP-TSKEVGTSFAQGPGVP-ATTTMT-PLAGLPRGYAAPASL
AS-----SPSSTSLGYGQTPTTANYGSQTEELPPTP-----SGRAAREKPLGVSDE----
--PSRGYSYYAGSSPPLSPSSPSESPTFSPGK------LGPRPTAEFSTQTPSPTPSSDL
PRSPSAPTQMPMVAQGTQTPHRPSTPRQAWQQSSQEAPLMVITLASEASSQTRMVHASAX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX--XXXXXX---
----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X----XXXXXXXXXXXXX-XXXXX
XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRHPTELLAPPLPMRRYSSVSNIYSDHRYGS
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGASG--GGPDLMQYQ-PQP
QPGP-----SAPQGLTPLRPGLLGNPTFPEGHPAPGSLAQYQPTAGQGP-AVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGAVTAVPIASLTRM
PVIAPRVPLGPPGIYRYPAPSRFPAAPSVPPPEGPLYLGKPAAAKAPG------------
-----AGAPPRPELPAGAAREEALSTAPAA--------TGKEAAVAGPAPVPLAGQKPPG
EA-VPGGVSGALGRPGLEKEEPSQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAGGDAPGRGPPPAPGE--------LAQNGQYWPPLTHA
TFI-AVAGPEGPAQPR-EPTLHRGLPSSASDMSLQTEEHWEAGRS-AIKKRHSMPRLRDI
CEPESAP-EPCVVKRIADSSVQTDDEEGEGRYLLTR-RRRTRRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDASGSSAATA------AAAAARPMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGRGESLACQTEPDSQ-AQGVAGPQL
IGPSAISPYLPGIQMVTPGA----------LGRFERKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDASFASSDRLNKAHVSPQKLFTADSTLRLQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLLQHQGGLGSQXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXX--X---XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX----XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-----XXXXXX-XXXXXX---------XXXXXXXXXXXXXXXXXXXPRFQ
LR--AQSC-RTERRGQNGFPAHQ----APTYPGSSTYPAAPAFPPCTSYPTEPTPPSQQA
FRPTG-------HYTAQTPMPSTQSTHYPVPADSRAPHQKPRQTSLADLEQKVPTNYEVI
ASPAVAMSSAPSETSYSGPAV----SYEQGKAPDMARAGDHGSVSLGPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLDPLGPS-SSGRPGKE-PGEPGGLEGPVL
PCCYTRGEEESEEDSYDPR-----GKSGHHRGVDSNGRS--------TSTHYYSDSDHRH
GARADKYGPGPVGPKHPSKSLAPAAVPSKRSKHRKQGIEQKISKFSPIEEAKDVESDLAS
YPSSAA--SGSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPVEEDDRMYSGSSR-S
RVSSAYSGEKLSSHEFSGRAKGYERE------------------REVMDRHQKGGSKPSS
LGMAHGRARPPMRSQTSEEESPVSPLGRP----RPAGGALPP--GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHTYKREEGYILDDSHCVVSDS---EAYHLGQEE---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

MPYQLALNSLASRWPSDGGSK-L-RIFSCQSDPGALRQKLPGQSPAQARPPH-------C
SQQVMPAFTPMTDS--LRC---------------ISNSHF--------------------
--QCHFSTSRRLDPKEPLGSQRAASPTPKQAS---ATTPGQESPQETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GL-------------------------QPGSRQGE--------
---MARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
---------------------LSTKASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RGLGSFEYQDTADRDYG-R
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPTGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMTDA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESVMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAVREEPLPPTTPA-AIKEAAGAPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESAA-EPCMVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTFFPVPADSRAQLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGSAV-SS-GYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAQQQ---Q
QQQ--------------QQQQQGLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGL------GP--GPGAGKPPSALA----G
GGQLPVAGAA-------RAAGPPTPGLGLVPGPGP----G--------------------
--PGPGSVSRRLDPKEPLGSQRATSPTPKQAS---ATAPGRESPRETR-AQGLSGQEAEG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RSPG----AT-------------------------QSGPRQAE--------
---AARATSVPGP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPAGEAQGKSATTVPSG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PTP--GAKTEPG----PR----------------------
------------TGPG----SGPGALAKTGGTPSPKHG-----RADHQA-ASKAAAKPKT
MPKERA-ACPLCQAEL-NVGSRGPANYNTCTACKLRVCTLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPL-PLPTPQQPPAGVPQRAAGASPLKQKGPQGPGQPSGSLPPKASP
QAAKAS---------------------PQAAKASPQAKPLRASEPSKTSS---------S
APEKKTGIPVKAEPVPKPPPETAVPP---GT--PKAKSGVKRTDPATPVVK-PVP-EAP-
--------------------------------------------------KSGEAEEPVP
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQAVAPSGE-WSKPPS---GSAVEDQKRRPHSLSIMPEAFDSDEELGD
ILEE--DDSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--DM
TDEEFMRRQILEMSAEEDNLEED-DTAV---SGRGLAKHGAQKASA--RPRPESSQESV-
-ALPKRRLPHNATTGYEELLSEEGPAEPTD-G--ALQGGLRRFKTIELNSTGSYGHELDL
GQGSDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPTRLYKSGSEYNLPAFMSLCSPTETPSGSSTTPSSGRPLKSAEE
AYEDMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTGP----RSQGSFEYQDTQDHDYGGR
ASQPAADGTPAG--LGATVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFPTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQEP-LKLHSSPASPSL-ASKEVGMTFSQGPGTP-ATTAMAPCPASLPRGYMTP---
AGPERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPAGSGRASREKPLSGGDGEVGP
PQPSRGYSYFTGSSPPLSPSTPSESPTFSPSKL--G----PRATAEFSTQTPSLTPSSDI
PRSPGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--ASHSYSQTTPPSASQMPSEPAGP-PGFPRA----------------
--PSAGVDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVTPLARRDILITQMGTAQSVSLKPG-PVPEPGAEP
HRATPAELRAHA---LPGTRKPHTVVVQMGEGAAGTVTTLLPEE-PAGALDLTGMRPESR
LACCDMAYKFPFGSSCTGTFHPAPSAPDKSVTDA--ALPGQSSGPFYSPRDPEPPEPLTF
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGGG--SGGPDLVPY-QPQH
GPGL-----NAPQGLASLRSGLLGNPTYPEGQPSPGNLAQYGPAASQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYGSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPIASTIPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPELPAGGAREEPLSTTAPPAVIKEAPVAQAP--------APPPGQKPAG
DAA-AGSGSGVLGRPVMEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AVAGTEGPGQAR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-DPSTVRRIADSSVQTDDEEGEGRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHEASASSS-A-------AAAAARAMSSVGIQTISDCSVQ
TEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
IGPTAISPYLPGIQIVTPGAL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKQFIADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-VGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAATQYTA-GSSGPTQNGFLAHQ----APTYTGPSTYPA-PTYPPGTSYPAEPGLPSQPA
FHPTG-------HYAAPTPMPTTQSAPFPVQADSHAAHQKPRQTSLADLEQKVPTNYEVI
SSPAVTVSSTPSETGYSGPAV-SS-SYEHGKAPEHPRGGDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTASDSQRPEPLGPGGVSGRPGKD-PGEPAVLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP--------ASTHYYSDSDYRH
GARADKYGPGPMGPKHPSKNLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PTVSSSLTSRSRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSR-S
RVASAYSGEKLSSHDFSSRSKGYERE------------------RETAERLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHTVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HGDHGRHS-----GRHAGE-------------------EPGRRAARPHARDMGRHETRPH
PQASPAPAMQKK--------GQPGY--------PSSADYSQPSRAPSAYHHASDSKKGS-
RQAHSGPTVL------QPKPEAQAQPQM-QGRQAVPGPQQSQPPSSRQTPSGTASRQPQT
QQQQQQQQQQQ--QQQQQQQQQGLGQQA----PQQAPSQARLQQQS--------------
QPTTRSTAPAA-SHPAGKPQ-PGPTTAPGPQP--------AGL-----------------
----PRAEQAGSSK-PAA--------------KAPQQGRAPQAQSA--PGPAGAKT---G
ARPGGTPGAPAGQPAAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGL------GP--GPGAGKPPSALA----G
GGQLPVAGAA-------RAAGPPTPGLGPVPGPGP----G--------------------
--PGPGSVPRRLDPKEPLGSQRTTSPTPKQAS---AAAPGRESPRETR-AQGPSGQEAES
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERSPRGPG----AT-------------------------QSGPRQAE--------
---AARATSVPGP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPAGEAQGKSATMVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PTP--GAKTEPG----AK----------------------
------------TGPG----SGPGALAKTGGTASPKQG-----KAEHQA-VSKAAAKPKT
MPKERA-ACPLCQAEL-NVGSRGPANYNTCTACKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPP-PLPTPQQPPAGVPHRAAGAAPLKQKGPQGLSQPSGSLPAKASP
QATKASPQAT-------KASPQATKASPQTTKASPQAKPLRASEPSKTSS---------S
TQEKKAGTPAKAEPVPKPPPETTVPP---GT--PKAKSGVKRTDPATPVVK-PVP-EAP-
--------------------------------------------------KGREAEEPVP
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SLRPSLEAQAVAPSAE-WSKPPRSS-SSAVEDQKRRPHSLSIMPEAFDSDEELGD
ILEE--DDSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--DM
TDEEFMRRQILEMSAEEDNLDED-DTAV---SGRGLPKHSAQKASA--RPRPESSQE---
---PKRRLPHNATTGYEELLSEAGPAEPTD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEDMMRKAEMLQ-RQQGQVAGARGPHGGP-SQPTGP----RSQGSFEYQDTQDQGYGGR
ASQPAAESTPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPVSSTL-ASKEVGMTFSQGPGSP-ATTAS------PTRGYMTPTPP
GGSERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPPGSGRAPREKPLSAGDSEVGA
PQPSRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----SRATAEFSTQTPSLTPSSDI
PRSPGP--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPLMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--TSHSYSQTTPPSASQMPSEPAGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVTPLARRDILITQMGTAQGVGLKPG-PVPEPGAES
HRATPVELRSHA---PPGTRKPHTVVVQMGEGAAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVTNA--ALPGQSSGPFYSPRDPEPPEPLTF
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPLRRYSSVSNIYSDHRYSS
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--SGGPDLVQY-QPQH
GPGL-----SAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQA-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAP-RFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPELPAGAAREEPLPTTAP-AVIKEAPVAPVPAP------APPPGQKPAG
EAA-AGSGSGVLGRPATEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQLQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHA
AFI-AVAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEDQWEAGRS-GIKKRHSMPRLRDI
CEPESGP-DPSTVRRIADSSVQTDDEEGEGRYLVTR-RRRTRRSADCSVQTDDEDNADWE
QPVRRRRSRLSRHSDSGSDSKHDAAASSS-T-------AAATARAMSSVGIQTISDCSVQ
TEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
IGPTAISPYLPGIQMITPGAL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKQFIADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYTA-GSSGPTQNGFPAHQ----APTYTGPSTYPA-PTYPPGTGYPAEPGLPSQPA
FHPTG-------HYAAPTPMPTTQSAPFPVQADSRAAHQKPRQTSLADLEQKVPTNYEVI
GSPAVTMSSAPPETGYSGPAV-SS-SYEQGKAPEHPRGGDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTASESQRLEPLGPGGVSGRPGKD-LGEPAVLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP---------STHYYGDSDYRH
GARADKYGPGPMGPKHPSKSLAPAALSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGSSSR-S
RMASAYSGEKLSSHDYSSRGKGYERE------------------RDTAERLQKAGSKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYMLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHTVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDMGRHEARPH
PQASPAPAVQKK--------GQPGYP---SGY-PSSADYSQPSRAPSAYHHASESKKGS-
RQAHTGPSAL------QPKADTQAQPQM-QGRQAAPGPQQSQPPSSRQTPSGTASRQPQT
QQQQQQ--------QQQQQQQQGLGQQA----PQQAPSQARLQPQS--------------
QPTTRGAAPAT-SQPAGKPQ-PGPTTAPGPQP--------AGP-----------------
----PRAEQASSSKPPAA--------------KAPQQGRAPQAQPTPGPGPAGVKP---G
ARPGGTPGAPAGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG-PLPPGGAGPGP--GPGPGPGPGAGKPPSAPA----G
GGQLPAAGA-------ARSTAVP---PVPG--PGPGPGPG--------------------
--PGPGSTSRRLDPKEPLGSQRAASPTLKQAS---ATTPGHESPQETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQAL
GKPDQERS-RGPG----GP-------------------------QPGSRQAE--------
---TARATSVPGP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEASAKSATAVPAG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGTPKIVFNDASK
EAGPKPLGSGPGPG------PAP--GAKTEPG----AR----------------------
------------M---GPGS-GPGALPKTGGTISPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRVSGTSPLKQKGPQGLGQPSGPLPAKASP
----------------------------LPTKASPQAKPLRASEPSKTPS---------S
AQEKKTRVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGPAPS-E-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEEE-DTAT---SGRGLAKHGTQKGGP--RHRPEASQEPA-
-ALPKRRLPHNATTGYEELLPEGGSAEATD-GSGTLQGGLRRF-TIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGSP-SQPTGP----RSPGSFEYQDTADREYG-Q
AAQPAAEGTPAS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPTSPSS-ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHRYGHSPTTANYGSQTEDLPQAPSGLAAAAQAAREKPLSASDGEGGT
PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKM--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTETQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRV----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQ--EHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAQYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGHG-TAIRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-------
----------RPEMPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPA
DA-APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRS-GIKKRHSMPRLRDA
CELESGA-EPCVVRRIADSSVQTDDEDGEGRYLLSR-RRRVRRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADGALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQFMDFTATAA---A--P---------ATPSGPTAFQQPRFQ
PPAPQYSA-GSGGPTQNGFPAHQ----APTYPGPSMYPA-PAFPPGASYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPAV-SS-SYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASTHYYGDSDYRH
GARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSSRDAVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHR-
HGDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAVTKK--------GQPGY--------PSSAEYSQPSRAPSTYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQIPSGAASRQPQT
QQ------------QQQQQQQQGLGLQP----PQQALTQARLQQQS--------------
QPTTRGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KALQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG---------PLPPGGSGPGPGPGAGKPPSALA----G
GGQLPATGGA-------RATAGP-----AGPGPGPGGGPGRP------------------
SPGSRAPVPRRLDPKEPLGSQRAASPTPKQPS---ATTPGRESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------GLSPSHSPAKQPL
GKPEQERA-RGPG----GP-------------------------QPGPRQAE--------
---TARATSVPGP-APAAAPPEVGKVSPQPSL-PIKPSTAEPRPPAGEAPAKSATAAPSG
PGAAEPT-QEGLTGKLFGLGASLLTQASTLMSA-QPEADSQGQPAPSKGPPKIVFSDASK
EAGPRPPGSGPG--------PGPTTGAKTEP-----------------------------
---------------G----SGPRAQARTGGTTSPKHG-----RTEHQAA-SKAAAKPKT
TTKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLP-LPSSQQPPAGAPHRTAGTAPPKQKGPQGLGQPSGPPPAKATP
LPTKAS--------------PLPTKASPLPTKASPQAKPSRASEPSRTPS---------S
AQEKKIGVPAKAEPVPKPPPETTLPP---GT--PKAKAGVRRTEPTTPITK-AVP-EAP-
--------------------------------------------------KGGETEAGEC
G--------------------EGFSSLR--------------------------------
-------------------------------------------DW---------------
--DI-EPGTALWAREDSRA----------TLLRH--------------------------
-------------------------------GGPGA------------------------
-------------CGFSSLL------------------------PLDL--VTLLFENLDM
EP----------------V---------------------SYAS----------------
-------------------------------PEQWSGWWALIQLLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEAPE-GGPGRLYKSGSEYNLPTFMSLYSPTETPSGSATTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAVGRGPHSGP-SQPVAP----RAQGSFEYQDSPDRDYSG-
VAQPAAEGTPAG--LGAAVYQEILQTSQSIARMHQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFATST--TSDSSGGRVIPDVRVTQ-HF
AKEPQDP-VKLHSTPASPSS-TSKEVGIGFAQGLGAS-ASMAVTPSPAGLPRGYMAPTSP
AASERSLSPSFAGHGYGQSPATANYGSQTEELPQAPRGPAVSGRATREKPLGMSEGESGP
PQTSGGYPYFAGSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSLTPASDT
PRSPGAPAPTPTVAQGTQTPHRPSTPHLVWQQSSQDAPFMVITLASDASSQTKMVHASAS
TSPVCSPVDTQP--ITHSYSQTTPPSESQ-PPEPPGP-PGFPRA----------------
--PSAGADGPLAVYGWGALPAENISLCRISSVPGTSRVEPGPRAPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPRETKFARYNLSNQVAPLARRDVLITQVGPAQSVGLKSG-PVPEPGTEP
HRAAPTELRSHA---LPGARKPHTVVVQVGEGAAGTVSTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGSFRATPSAPERSVAEV--APPGQSSGPFYSPRDPEPPEPPTY
RAQVIGAPGPHDEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRFGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGV--GGPDLMQY---QP
QPGL-----SAPQGLAPLRPGLLGNPTFPEGQGSPGSLAQYRPTAGQA-ASVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYPPGGVAAVPLASLTRM
PVIAPRVPLGPTGLYRYPVPSRFPTPASVPPTEGPVYLGKPAAAKGPGTGGPP-------
----------RPELPAGAAREEPLSTAPPAAA-KETGA----------APALGAGQKPLG
EA-TPGGGGGALGRPGLEKEDALPEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTLKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKPPFPMAC-EAPGRGPPPA--------APEMAQNGQYWPPLTHA
AFI-AV--PEGSGQPR-EPMPHRGLPSSASDMSLQTEEPWEVGRSGGLKKRHSMPRLRDA
CEPESGP-EPCGVRRIADSSVQTDEEDGEGRYLLTR-RRRARRSTDCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSAA--------APTTRATSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAVTDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-AQGVAGPQL
MGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSAFRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFPLYQHQGGLGSQVSAPPPNGLVRKVKRTLPSPPPE
EAHLPLAGQAAPPQLYAASLLQRGLVGPAAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLSEHRDYLSDSELNQLR
LQGC----A------TPAGQYAEFPVTA-----AAP---------ATPSGSAAFQPPRFP
PPAPLYPA-GSAGPTQNGFAAHQ----APTYPGPSTYPA-PAFPPGTSYPAEPGLPSQQA
FRPPG-------HYTAQTPLPTTQTTLFPAPADSRAPHQKPRQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETSYSGPGPAASSSYEQGKAPELPRVSDRSGVSLSPAPIYSSDSHYTS
LEQTVPRNYVMIDDISELTKDSTSTAPESQRLEPLGPS-SSGRPAKE-PGEPGVLEGSAL
PCCYTRGEEESEEDSYEPRGKSGH-----HRGVESNGRP--------ASTHYYSDSDYRH
STRADKYSPGPAGPKHPSKSLAPAAVPSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--SAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPAEEDDRMYGGSSR-S
RGAPAYSGEKLSSHDFGGRAKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRTRPPMRSQASEEESPVSPLGRPR----PAGGP-LPP-GDTCPPFCSS-HSMPD
VQEHV-KEGPRSHSYKRDEGYILDDAHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHGYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHAGE-------------------EPSRRAAKPHVRDVGRHEARPH
PQPSPAPAVQKK--------GQPGY--------PSSAEYSQPSRAPSAYHHSSESKKSS-
RQAHPGPAAL------QPKLES--QPQP-QGRQAAPGPQPSQPPPSRQMPSATASRQPQT
QPQPQQGLGLQ-----------------P---PQQAPSQARLQQQG--------------
QPAARGPASAA-SQSAGKPQ-AGPPTATGPQP--------SG------------------
---PPRAEQANSSK-GTA--------------KAPQQGRPPQAQPPPGPGPAGVKA---G
AKPGGTPGAPAGQPGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGVGEG-PLPPGGSGP------GPGPGPGVGKPPSAPA----G
GGQLLAAGGA-------RATAGP-----PGPGPGPGPGPG--------------------
--PGPGSVSRRLDPKEPLASQKAASPTLKQPS---ATAPSHESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPERGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-QGPG----GP-------------------------HPGPRQAE--------
---TARATSVPGP-AQASAPPEVGRVSPQPSL-PIKPSTADPRPPAGEVPAKSATTVPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSA-QPEADSQGQPAPSKGPPKIVFSDASK
ESGPRPPGSGPGPG------PAP--GAKTEPG----AK----------------------
------------TGPG----SGPGALARTGGTTSPKHG-----RAEHQA-VSKATAKPKT
MPKERA-TCPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-PLLTSQQPPGGAPHRATGTAPPKQKGPQGLGQPSGPSPAKASP
LPTKASPLPT--------------KASPLPTKASPLPKPLRASEPSRIPS---------N
AQEKKIGVPAKAEPVPKPPPETPLPP---GT--PKAKAAVRRTEPASPAVR-AVP-EVP-
--------------------------------------------------KGGEVEEPVG
KPYSQELSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVSGQRPPSPSELH
KVGS-SMQPSLEAQGPVPSGE-RSKPPCS---S-SEEQKRRPHSLSIMPEAFNSDEELED
ILEE-EEDSLEWGHQREQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTTT---PGPGLAKHGSQKGGQ--RPRSEPGQEPG-
-TLTKKRLPHNATTGYEELLSEGGPAEVTD-GPGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEQSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPTRLYKSGSEYNLPTFMSLYSPTETPLGSTTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPQGGP-SQPIGP----RSQGSFEYQDTPDHDYG-R
AMQPASEDTSAS--LGAAVYEEILQTSQSIARMHQASSQDLAFVEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKESQDP-LKLHSSPAAPSS-ASKEVGISFSQGPGTP-ASTAVAPCPAGLPRGYVTLTSP
AGSERSLSPSSTGHSYGQSPTTANYGSQTEELPQALSSPAMSGWASREKPLSVSDGESGT
PQTSRGYSYFAGPSPPLSPSSPTESPTFSPGRL--G----PRATAEFSTQTPSPTPASDM
PRSPGAPALTPTVAQGTQTPHRPSTPRLVWQQPSQEAPFMVITLASDASSQTKMVHASAS
TSPVCSPTDSQP--TTHSYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--SSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAIKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSSATSVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRA--
----------RPREAKFARYNLPNQVASLARRDVLITQVGATQSVGLKSG-SVLEPGAEP
HRAAPAELRSHT---LSSARKPHTVVVQMGEGTAGTVTTLVPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSVPEKSVADV--APPGQGSSPFYGPRDPEPPEPPTY
RAQVVGGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRIGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDTAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGSGGSGPDLMQY-QPQ-
-PGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPGNLAQYRPTAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-SMYRPYASSGIAAVPLASLTRM
PMIAPRVPFGPAGPYRYPVPSRFPTASSIPPAEGPVYLGKPAAAKAPGA-GPP-------
----------RPELPAGAAREESLSTATPA-AVKEAMAAPAPAP----VPAPLAGQKPPV
DAA-SGGGGGALSRPGLEKEEVSQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPSRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AVAGPEGPGQPR-EAVLHRGLPSSASDMSLQTEEQWEAGRS-SIKKRHSMPRLRDV
CEQESGP-EPCVVKRIADSSVQTDDEDGEGRYVLTPRRRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSSSDSKHDATASSSTA--------TPTMRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGHGESLACQTEPDGQ-AQGVPGSQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----A------TPAGQYADFPVTA----A-AP---------ATPSGPTAFQQPRFP
PPAPQYAV-GSSGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAVQTPMPTTQSTLFPVPADSCAPHQKPRQTSLAELEQKVPTNYEVI
ASPVMAMSSAASETSYSSPAV-SS-SYEQGKAPELPRASDRSSVSLSPAPTYPSDSHYAS
LEQNVPRNYVMIDDISELTKDSASTAPDSQRLEHLGPS-SSRHPGKE-PGEPGVLEGPAL
PCCYARGEEESEEDSYDPRGKSGH-----HRNVESNGRS--------ASTHYYSDSDYRH
GARAEKYSPGPVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
SPS--PAVSSSLASRSRKFQDEITYGLKKNVCEQQRYYGMSSRDPMEEDDRMYGGSSR-A
RVASAYGGEKLSSHDFS-RGKGFERE------------------REAVERLQKVGPKPSS
LSMAHGRPRPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGPWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHAGE-------------------EPGRRAAKPHVRDVGRHEARPH
SQPSPGPAMQKK--------GQPVY--------PSSTEYSQPSRVLSAYHQASESKKGS-
RQAHSGPTTL------QPKPEP--QPQP-QGRQAAPGPQQSQPPPSRQMPSATASRQPQT
QQQQQQ----------QQQQQQGLGPQP----PQQALSQARLQQQG--------------
QPASRGLAPAA-SQPVGKPQ-PGPSTATGPQP--------AGP-----------------
----PRAEQVNGSK-GTA--------------KAPQQGRAPHAQPPPGPGPAGVKA---G
AKLGGNPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGL------GP--GPGAGKPPSALA----G
GGQLPVAGAA-------RAAGPPTPGLGPVPGPGP--GPG--------------------
--PGPGSVPRRLDPKEPLGSQRTTSPTPKQAS---ATAPGRESPRETR-AQGPSGQEAES
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERSPRGPG----AT-------------------------QSGPRQAE--------
---AARATSVPGP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPAGEAQGKSATTVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PTP--GAKTEPG----AR----------------------
------------TGPG----SGPGALAKTGGTASPKHG-----RAEHQA-ASKAAAKPKT
MPKERAAACPLCQAEL-NVGSRGPANYNTCTACKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGGPAPL-PLPTPQQPPAGVPHRAAGAAPLKQKGPQGLGQPSGSLPAKASP
QATKASPQ--------------ATKASPQTTKASPQAKPLRATEPSKTSS---------S
AQEKKTATPAKAEPVPKPPPETTVPP---GT--PKAKSGVKRTDPATPVVK-PVP-EAP-
--------------------------------------------------KGGEAEEPVP
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSDLH
KVGS-SLRPSLEAQAVAPSAE-WSKPPRSSSSSAVEDQKRRPHSLSIMPEAFDSDEELGD
ILEE--DDSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--DM
TDEEFMRRQILEMSAEEDNLEED-DTAV---SGRGLAKHSAQKASA--RSRAESSQE---
---PKRRLPHNATTGYEELLSEAGPAEPTD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEDMMRKAEMLQ-RQQGQVAGARGPHGGP-SQPTGP----RSQGSFEYQDTQDHDYGGR
ASQPVAESTPAG--LGAAVYEEILQTSQSIARMRQASSRDLAFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPVSSTL-ASKEVGMTFSQGPGSP-ATTAS------PTRGYMTPTSP
AGSERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPPGSGRVPREKPLSGGDSEVGV
PQPSRGYSYFTGSSPPLSPSTPSESPTFSPGKL--G----SRATAEFSTQTPSLTLSSDI
PRSPGP--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPIMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--TSHSYSQTTPPSASQMPSEPAGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREPKFARYNLPNQVTPLARRDILITQMGTAQSVGLKPG-PVPEPGAEP
HRATPAELRSHA---PPGTRKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVTDA--ALPGQSSGPFYSPRDPEPPEPLTF
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPLRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--SGGPDLVQY-QPQH
GPGL-----SAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQA-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAP-RFPIASSVPPAEGPVYLGKPAAAKSSGAGGPP-------
----------RPELPAGAAPEEPLSTTAP-AVIKEAPVAPAPGPAP----APPPGQKPAG
EAA-AGSGSGVLGRPAAEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQLQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHA
AFI-AVAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-DPSTVRRIADSSVQTDDEEGEGRYLVTR-RRRTRRSADCSVQTDDEDNADWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTT--------AATARAMSSVGIQTISDCSVQ
TEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
IGPTAISPYLPGIQIVTPGAL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-M
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKQFIADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDYPASA----A-VP---------ATPSGATAFQQPRFP
PAAPQYTA-GSSGPTQNGFPAHQ----APTYTGPSTYPA-PTYPPGTGYPAEPGLPSQPA
FHPTG-------HYAAPTPMPTTQSAPFPVQADSRAAHQKPRQTSLADLEQKVPTNYEVI
GSPAVTMSSAPPETSYSGPAV-SG-SYEQGKAPEHPRGSDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTASESQRLEPLGPGGVSGRPGKD-PGEPAVLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP---------STHYYGDSDYRH
GARADKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGSSSR-S
RMASAYSGEKLSSHDYSSRGKGYERE------------------RDTAERLQKAGSKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYMLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHTVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHTRDMGRHEARPH
PQASPAPAMQKK--------GQPGY--------PSSADYSQPSRAPSAYHHASESKKGS-
RQAHTGPSAL------QPKADTQAQPQM-QGRQAAPGPQQSQPPSSRQTPSGTASRQPQT
QQQQQ-----------QQQQQQGLGQQA----PQQAPPQARLQPQS--------------
QPTTRGAAPAA-SQPAGKPQ-PGPTTAPGPQP--------AGP-----------------
----PRAEQASSSKPPAA--------------KAPQQGRAPQAQPTPGPGPAGAKP---G
ARPGGTPGAPAGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SISRRLDPKEPPSSQRAASPTPKQAS---ATAPGRESPRETRAAQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRSSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------VLSPAHSPAKQPL
GKPEQERS-RGSG----VS-------------------------QPGSRQAE--------
---TARATSVPGP-AQVTAPPEVGRVSPQPSV-PTKPSVAEPRPPSAEAPAKSATAVPSG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADSQGQPAPSKGPPKIVFSDASK
DAGPRSLGSG----------PAP--GAKTEPG----AR----------------------
------------TGLG----SGPGALPKTGGTTSPKHG-----RAEHQAASKA-AAKPKT
MLKEKA-TCPLCQTEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLPLPTSQ-QPPMGAPHRVAGTTPLKQKGPQGMGPPSGPLPAKAS-
--------------------PLPTKASPLPTKASPQAKPLKASEPSRTPS---------S
AQEKKIGVPTKAEPVPKPPPETTPSP---GM--PKIKSVGRKAESATPVVK-AVP-ETP-
--------------------------------------------------KGGEAEEPVG
KPYSQDVSRSPQSLSDTGYSSDGVSSSQSEITGVV-QHEVEQLDSAGVTGPRPASPSEIH
KVGS-SMRPLPEAPGLASTVE-QSKPPCS---STGEEQTRRPHSLSITPEAFDSEEELED
ILEE-EEDSLNWRHRKEQQDAAESSDDYGSQLRHDYVEDSSEGGLSPLPPKPPART-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGHGLAKYGTQKGAP--RPRPEPNQEPA-
-ALPKKRLPHNATTGYEELLSEGGPAEATE-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDTNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-SGPSRLYKSGSEYNLPTFMSLYSPTEMPSGSSTAPSSIRPLKSAEE
AYEEMMRKAELLQ-RQQGQVSGTWGPQGGP-SQPTGP----RGQGSFEYQGAPDHEYG-P
AAQSASEGTPAS--LGTATYEEILQTSQSIARMRQTSSQDLGFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTS--TSSDSSGGRVIPDVCVTQ-HF
AKEPQEP-LKLHSSPASPSS-ASKEVGMSFSHGPETP-ATTAMAPCPASLPRGYISPTSP
AVSERSPSPSSIGRNYGPSPATANYGSQTEELPRTPSSPAAGGRAAREKTLSESD-EGAT
SQPSRAYSYFAGPSPPLSPNSPSESPAFSLGKL--G----PRATAEFSTQTPSPTPASDM
PWSPGTPTPTPMVAQGTQTPHQPSTPRLVWQQSSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTDTQP--TTHSYSQTTPPSVSQLSSEPPGP-SGFPRM----------------
--PSVGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGSAVVDLRTAIKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHALLGTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQGVQTAPYRGGSRG--
----------RPKEAKFARYNLPNQVVPLARRDVLIT-----QSVGLKPG-PVPEPAAEP
HRAIPAELRSHA---LPGVRKPHAVVVQMGEGTAGTVTTLLPEE-PTGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSVPEKSMADA--APPGQSSGPFYGPQDPEPLEPPTY
QAQGPVGPGPAEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRVGQLFQGPGRDSAVD
LSSLKHSYRLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPMRRYSSVSNIYSDYRYGQ
RGDVVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGTDLVQY-QPQH
RPRI-----TASQSLAPPRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPTGLYRYHVPSRFPIASSVPSAEGPVYLGKPAAAKSTGAGGPP-------
----------RGELPTAAAREESLSITTPA-AVKEAVGAPAS--------SPLTSQKPPG
DA-PLGGGSGVLNRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPGRGPPPA--------ATELAQNGQYWPPLTHT
AFI-AVAGPEGPGQPRGEPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-EPCMVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSST--------ATAAARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHIIAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVIGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQTHLPAESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTTDSTLHQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQG-PPQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----S------TPAGQYMDFPATAV---A--P---------ATPSGPTVFQQSRFP
PPASQYTA-GSGGPTQNGFPAHQ----PLTYPGPSTYPA-SAFPPGTSYAAEPGLPNQQS
FHPTG-------HCAAQTPMPTTQSTLFPVPAESRAPHQKPRQTSLADLEQKLPTNYEVI
ASPVVAISSAPSETSYSGPAV-SS-GYEQGKAPELPRATDRGSVSQSPAPTYPSDSHYTN
LEQNVPRNYVMIDDISELTKDSTSTASDSQRLEPLAPG-SSGRPGKE-PGEPGVLEGSAL
PCCYGRGEEESEEDSYDPRGKVSH-----HRNMESNGRP--------ASTHYYSDSDYRH
GTRAEKYSPGPIGPKHPSKSVAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSTRDLVEEDDRMYGGSSR-S
RISSAYSGEKLPSHDFSGRGKGYERE------------------REAVERLQKTSPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDSEVSEAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HSDHGRHS-----SRHTGE-------------------EPGRRAAKPHARELGRHEARPH
PQPSPAPVMPKK--------GQSGY--------PSSAEYSQPSRVPSAYHHASDSKKGS-
RQAHSGQAAL------QPKQEPQVQPQL-QGRQATPGPQQSQPLSSRQMPSGAASRQPQ-
--------------TQQQQQQQGLGLQQ----SQQALSQARLQQQS--------------
QPATRGPAPTAS-QPVGKPQ-PGPTTAAGPQP--------AGL-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGSGPAGLKA---G
ARPGGPPGAPAGQPGTEGESMFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG---------PLPPGGPGPGPGPGAGKPPSAPA----G
GGQLPTAGAA-------RATAGP---PGPGPGPGPGPGPS--------------------
--SGSGSASRRLDPKEPVGSQRAASPTPKQAS---TTAPGRESPRETR-AQGPAGQEADG
PRRTLQ------------------------------IAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVRVYICMRCCGCGMCGLRELLEAVPALSTPQPL
PPDSLRPRTFAELVLLKQQSRSRDENPAQNASFWTKRSVNSEPLAKSPVLLQGLPAPFQP
SIFHAVTQPLPLLPTSLSFPERARAPDGPGVVLKYPPLFSQRWKRPSSVSTSSRPRQTKF
PAQSRTPEALEGDNRKVTEAFQPQGSHPEPQEAETHFPGPPSGSLISGQTAGVRETKQPL
GKPEQERS-RGPG----GP-------------------------QPGPRQAE--------
---AARATSVPGP-AQAAAPPEVGRASPQPPH-PTKPSTTEPRPPAGEAPAKSATAAPSG
PGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQGQAAPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PVS--GAKTEPG----AR----------------------
------------TGPG----SGPGALAKTGGTTSPKHG-----RAEHQAA-SKAAAKPKT
MPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGGLGEPTPLPLP-TSQQPLRGP--LTVPLEPPKQKGPQGPSQPPGPLPAKASP
LPTK---------------------TSPLPTKASTQSKPLRASEPSKTPS---------S
AQEKKTGVPAKAESVPKPPPETTPPP---GA--PKVKSGVRRIEPAPPVVK-AAP-EAPK
GGEAEVSPFIPMSPTCQIGTVSGGACLPGRLKMQAWARPCGATEEGRVAPAEGKPEEPVG
KPYPQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-RQEVEQLDSAGVTGPRPPSPSELH
KVGS-SMRPLLETQGLAPSGGERSKAPSS---STGKEQKRRPHSLSIMPEAFDSDEELED
ILEE-EEGSLQWQRQREQRDAAESSDDFGSQLRHDYVEDSSEGGLSPVPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEDD-DTAT---SGHGLAKPGTQKGGP--RTRPEPGQEPV-
-ALPKRRLPHNATTGYEELLSEAGPSEDTD-GSGSLQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEE-LREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPVGSAPTPSAARPLKSAEE
AYEEMMRKAELLQ-RQQGQGPGARGPHAG--------------QGAFDYQDTPDRDYG-R
AAQPAPEGPPAG--VGTAVYEEILQTSQSIARMRQASSRDLAFAEDKK--------KEKQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--PSDSSGGRVIPDVRVTQ-HF
AKEPQEP-LRLHSSAASPSS-ASKEAGVSVSQGPGAP-ATPAVAPCPAGLPRGYITPAPA
AGSERIPPPSSAGHGYGPSPSTANYASQTEELPQAPGGTAAGGRASREKSLSGGDGDIGT
PQTSRGYSYFVGSSPPVSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSAVPALDM
PRSPGAPTYTPGSPVVNIHTST-QFTSPGGSSPLRRQPIMVITLASDASSQTRMVHASAS
TSPLSSPTDTQP--TAHSYSQTTPPSGSQMPPEPPGPLAS-HGH----------------
--PVLGQTGPWPCMA-GAPSLLRTSPCAGSPLSLEHPVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAAEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLGTATTVSI
TMSSSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQMAPLARRDVLITQMGTAQSVGLKAG-PVPEPGAEP
HRVTPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPEKSVSDA--APPGPSSGPFYGPR----------
-------------------GLPGRLYSSMSDTNLAEAGLNYHAHRIGQLLQGAGRDSAMD
LSSLKHSYSLGFTDGRYTTGM-AHGEMQLV------------------------------
------------------------------------------------------------
----------------------SKRPVWPS-----------------T-VPPRPVRSAAS
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLTSLTRM
PIIAPRVPLGPPGLFRYPAPGRFPIASSVPPAEGPVYLGKPAAAKAPGTGGPP-------
----------RPELPAGAAREEPLSTTTPA-AVKEAVAAPAS--------APLAGQKLPG
DA-APGAGSAALSRPGPEKE----------------------------------------
-----------------------EIKHHVLQQQQEERQAQFALQREQL------------
-----------------APFPAAC-EAPGRGPPPA--------APELAQNGQYWPPLSHT
AFI-AVAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWETSRA-GIKKRHSMPRLRDA
CESEPGP-EPGAVRRIADSSVQTDDEDGEGRYLLPR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRTRLSRHSDSSSDSKHEATASAPPA--------AAAARAVSSVGIQTISDCSVQ
TEPDPLPRVSPAIHITAATDPKVEIVKYISAPEKTGRGESLACQTEPDAQ-AQAVAGTQL
VGPT-----------------------------FEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFAADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLAGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------APAGQYGDFPATAA---A--P---------ATPSGPTAFQQPRFP
PPAPQYTA-GSAGMTQNGVPAHQ----APTYPGSSTYPA-PAFPPGTSYPTEPGLTNQQA
FRPTG-------HYTAQTSMPATQSTHFPVPADSRALHQKPRQTSLADLEQKVPTNYEVI
TSPVVAVSSATSETSYSGPAVS--SSYEQGKVPELPRASDRSGVSQSPAPTYPPDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPESQRLDPSGPGG-SGRPGKE-PGEPGILEGSAL
PCCYARGEEESEEDSYEPRGKVGH-----HRSVESNGRP--------ASAHYYSDSDYRH
GARAEKYGPGPSGPKHPSKSLAPAAIPSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--SAVSSSLASRGRKFQDDITYGLKKNVYEQQRYYGVSSRDAVEEDDRMYGGSSR-S
RGASAYSGEKLSSHDFSGRGKGYERE------------------RETVERLQKAGPKPSS
LSMAHSRGRPPMRSQASEEESPVSPLGRPR----PAGGT-LPP-GDSCPAVSAPATPLPD
VQGARQRTGLGPTRISVKEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPSEEGLWAPDEGGPGRHASAKEHRH
HSDHGRHS-----SRHTGE-------------------EPGRRATKPHARDMGRHEARPH
PQPSPAPAMPKK--------GQPGY--------PSSAEYSQPPRVPSAYHHASDSKKGS-
RQAHSGPAAL------QPKPEPQAQPQAAPGRQTTPGPQQSQPPPSRQLPSGAATRQPQP
QPQQQ-----------QQQQQQGLGQQP----PQQAPPQARLQQQS--------------
QPSARGPAPAS-SQPAGKPQ-PGPTPAAGPPP--------AGP-----------------
----PRAEQANGSK-ATA--------------KAPQQGRAPQAQPTPGPGSAGLKT---G
ARPGGAPGAPAGQPGADGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG-PLPPG--------------GPGAGKPPSALA----S
GGQLPAAGAA-------RAVGPPQVS-DLVPG--PGSGPD--------------------
--PGPGSSSQRLDPKEPLGSQRAASPAPKQAS---ATAPGRESPRETK-TQGPSGQEADG
PRRTLQVDSRTQQSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERS-RGPG----GQ-------------------------QPGPRQAE--------
---TARATSVPGP-TQATAPPELGRVSPQPPF-STKPSTAEPRPPAGEAQGKSATTVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPETETQSQPSPSKGPPKIVFSDASK
EAGPRPPVSGPGSG------PTP--GAKTEPG----AR----------------------
------------TGPG----PGSGALAKTGGIASTKHG-----RAEHQA-ASKAAAKPKI
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPDLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-PMPTSQQPPAGARHRAVGPAPPKQKGPQGLGQPSGPLPAKASP
L----------------------------PTKASPQAKPSRASEPSKTSS---------S
AQEKKTGVPTKAEPVPKPPPETT------GT--PKAKSGVRRTEP---VTK-PVP-EAP-
--------------------------------------------------KGGEAEEPIS
KPYTQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGHRPPSPSELH
KVGS-SMQPLLEAQAVAPGGE-RSKPPSS---SAVEDQKRRPHSLSIMPEVFDSDEELGD
ILEE-DEDSLGWGHQKEQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--EM
TDEEFMRRQILEMSAEEDNLEEN-DSAV---SGRGLAKHGTQKGST--RSRTEPSQEPT-
-ALPKRRLPHNATTGYEEPLSEGGPTEATD-SSVALQGGLRRFKTIELNSTGSYSHELDL
GQGPDSSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSDSSTTPSSGRPLKSAEE
AYEEMMRKAEMLQ-RQQGQVAGVHGPHGGP-SQPTGP----QGQGSFDYQDSPDHDYG-R
ASQPGAEGTPVG--LGANVYEEILQTSQSIARMRQASTRDLAFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHTSPASPSL-ASKELGMSFSQGPSTP-ATTAMAPSPASLPRGYMTPTSP
AGSERSPSPFSTVHSYGQTPTTANYGSQTEEPPQVPSGSIVGGRVTREKPLSGNDGEVGT
PQPSRGYSYYSGSSPPLSPTTPSESPAYSPGKL--G----PRATAEFSTQTPILTLASDM
PRSPSTPTPSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASAS
TSPLCSPTDTQP--TTHTYSQTTPPSGSQLPSEPSGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRLPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSMLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGSRG--
----------RPREAKFARYNLPNQVTPLARRDILITQMGTSQSVSLKPG-PVPETGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PVGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFPPAPSAPEKNMADA--VPPGQSTGPFYSARDPEPSEHLTY
RAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRIGQLFQGPGRDSAVD
LSSLKHSYSLGFADERYLGQGLQYGSFTDLRHPTDILTHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHVSG--GGGPDLVQY-Q--H
APGL-----SAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAGSQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GVYRPYASGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRYPIASSVLPAEGPVYLGKPAAAKAPGAGGPP-------
----------RPELPSGAAREEPLSTTAP-APIKEAPVASAPAPL--------PSQKPPG
DAA-AGGGSGVLNRPGMEKEETSQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPATC-EAPGRGPLPA--------ATELAQNGQYWPPLTHT
AFI-AVAGTEGPGQPR-EPMLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-EPCTVRRIADSSVQTDDEDVEGRYLLTR-RRRTRRSADCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSS-A-------ATTTVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDAQ-AQGVAGPQL
VGSTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVTPQKHFMADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PSQLYAASLLQRGLVGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------MPTGQYVDFPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYTA-GSSGPTQNGFPAHQ----APTYTGPSTYPE-PSFPSGTSYPAELGLPNQQG
FHPTG-------HYAAQTPMPTTQSTLFPVQADSRAPHQKPHQTLLADLEQKVPTNYEVI
TSPAVTMSSVPSETSYSGPAV-SS-SYEQGKAPELPRSSDQSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTAHDSQRLEPLGPSGVSGRPGKE-PGEPGVLEGSTL
PCCYGRGEEESEEDSYDPRGKASH-----HRSMESNGRP--------ASTHYYSDSDYKH
GSRTEKYGPGPMGPKHPSKSPGPAVISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--TAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYSGSSR-S
RVASAYAGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRTRPPMRNQASEEESPVSPLGRPR----TAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KEGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHVSAKEHRH
HSDHGRHS-----VRHVGE-------------------EPGRRAAKPHARDLGRHETRPH
PQASPAPSMQKK--------GQPGY--------LSSAEYSQPSRAPSTYHHASDSKKGS-
RQAHSGPATL------QPKPEPQAQPQM-QGRQAAPGPQQSQPPPSRQMPSGTTSRQPQI
QQ---------------QQQQQGLGQQL----PQQAPSQARLQQQS--------------
QPNTRGSAPAA-SQPAGKPQ-PGPMTAPGPQP--------AGL-----------------
----PRAEQANGSK-ATA--------------KTPQQGRAPQTQPTPGPGPTGLKA---G
ARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------MSRRLDPKDHPDGQRVTSPIPKQAA---AH-SHEGRRREM------GGPQVDG
PHRTLQVDSRMQRTGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTTDLTSSPNQ
PNFNTCTQCHNKVCNQCGFNPNPHLTEXXXXXXXXXXXXXXXXXXX---XXX--------
------XXX------------------------------------XXX------------
------------------------------------------------------------
--------------------------------XXXXXX---------XXXXXXXXXXXXX
XXXX------------------XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXX--XXXXXX-XX-----XXXXXX---------------------XXX---XXXXXX
-XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX-------XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX---------XX------XXXXXXXXXXXXX-X------XXXX
XXXXXXX----XXXXXXX----XXXXXXXXXX---X-----XXXXXXXX-XXXXXXXXXX
XXXXXX-XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKNEWLCLNC
QTQRLLEGSLGDPVPTPLP-TPKQTPTSSPRHQPGPSPQKQKGPPAPGPGQPA-------
-------------------------GP---TPLSLQTKHLRASEPSKPPS---------G
PQEKKPSGPAEAKQVPKPSPLPTTLT-----EAPKTKDGPKRAEPPLADSKGISIAEAP-
--------------------------------------------------RG-SEQEDPS
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGLV-QQEEEQLNTAGVVKPSPPSPSELN
KLES-TMRPLLEAQGGAPAEQAKAPPS------TGGKQRQRPRSLSITPEAFDSDEELED
ILEE-DEDSLEWENQRDARDAAESSDDFGSKLRHDYVEDSSEGGLSPLPTRPAGRD-AEG
PDEDFMRRQILEMSAEEDNLEDDD-------AEYDRAKYSLRKAAS--KPGPEQGQEP--
-APPKRRLPHNAS-TYEEELKDVGAPEPE--DVAALQGGLRRFKTIELNSTNNYGREMEI
SQEADISLDREPELEMESLTGSPEDRSRGEYSSTLPATTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEVKQQMNARHRSHGPLLPTIEDSSEEEXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEGFE-IGPSKLYKSGSEYNLPTFMSLYSPTEKTSSST-TTS-SKPLKSAEE
AYEEMMRKAELLQK-QQAAQL--SSSYG-GS-------GPRRGQGSFEYQYIEDY--VSS
QLGSSQTM---SLRLAGAVYEEILQTSQSIARMHQASSRDLAFQE--NEK------KEKQ
FLNAESAYSELMRQNGGALTPGTSPTQLAAPVSFSS------DSGGSRVIPDVRVTQ-HF
AKETQDA-LKLLSSPASPSS-ALKGVTAAFTYSKGAP-LVTTVASSIASRPRVYTAAM--
-------SP---GGPEP-HPTTASYGSQTEEMPQAQVLPDTGGLPGRERLQSMSDSKTGA
PLSSKGYPGFKSASPPLSPTSPMEGLPPAIGR------MGPKSTAEFSTQTHSPLLPSDI
PRSPISSTPSSMVAQGTQTPHRSSSPRLTRQQSSQESPFMVITLASDAASQTKLVNASSS
TSPASSPTRH--QPTIHSYSQSVQVNGTQFQQEQPL--HSFPRV-----SSAIVPMNAAK
GHMA--------PYGWGSLPAENISLCRISSVPGTSRVEPGPKPPTSSAVDLRTAMKSTP
IIITDRGMDLTSLAAEARKYCLTLDQSPGRQSTTVQPLIINLNAQEHTHTFIGTSTTVSI
TVASSMLVSQPKQPVVYGDPFQNRLDFGQGAGSPVCLAPVKHVEQAVQTGPYQGGPRGKP
-----KE-------AKFARYNLPNQMAPLVKKDILVTQMSATQNIS--IKPYPMEPSSDA
YRGTPAELKAHSVPTHVSGKKPHMMMVQMDDMTAGAVTKLVKEEP-TSALDLTGIKPESQ
VACCDVVYKFPFSSSCTGTFHPSPKMPEKNVVDA--AQPSQSSLPFYGSREQDLPEPSPY
REQAAVGPRLYEEQKLYSHGLMGRLYSSMSDTNLAEAGLSYYPHKSDQFFQPPGGDSAMD
LTTMKHSYSIGFD-GRYLPQGMQYGSFTDLRQAPDLMGHPLPMRRYSSASNIYSDYRYSP
RGDLSGFQESNLAQYSATTAREISRMCAALNSMD-QYGGRHS-----SSPELLQYPQPGP
GPSA-----SAQQGLAAIKPNMMMNPNFPEGRQSFGKLAQYSPAIGQGA-AGRELGPSTA
TVRAADGMIYSTINTPIASTLPITTQPASVLRPMVR--GIYRPYGPGSITPVPLASLTRV
PVVAPRVPLMPQGLYRYPAPSRFPAITTAPGIDGPLYLGKAGPAT---------------
--APGAGGLQRTEQPLGSTREE----PPAA--------ASVGPKEAVPAPSQLPGQKQPG
E-------V--TPEQGGAEKEEKEEERQRKQQEHLLQMERERVELEKLRQLRLHEELERE
RVELQRHREKEQMLVQREIQELQTIKHQVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQHQLEEQK-RQKAPFPPVC-DPSGRLPPQAVTE--------MAPNGQYWPPINQA
FMATAAMGMEGTGQPR-EPGPPRPLPSSASDMSLQTDERWEAGRG--LQKRHSMPRLRDA
YEMEEAHE-PYVVRKITDSSVQTDEEDGEERYFMSR-RRRTRRSTDCSVQTDDEDNADWE
QPVRRRRTRFSRHSDSVSDSKHDSSSSS--------------PRSKSSVGIQTISDCSVQ
TEPDQLLRVSPSIHITT-PDPKVEIIKYISAPEKTQKGESLACQTEPEAQ-VQGIVVPQL
PGPAAISPYTPSIQIVTTGP----------LGKFEKKKPDPLEIGYQSHLPTESLSQL-V
TRQPPKSPQVLYSPVSPLSPHRLLESSFASSERLNKAHVTPQKHFTADSAQRQQTVPRPM
KTMQRSLSDPKPISPTAEESAKERFSLYQQQVLQGSQMSAFQANTLIRKVKRTLPSPPPE
EAHMPLPSQA-HSQMYMASLLQKGLAGPP-VQVTKASLLKELDRDLKLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKGSLMKDR-AGRDYPYLRCLGENRDYMSDSELNNLR
LWGC----------TAPANQYSDFAATQYTSASSP----------ITPPAPTAFQHTRFQ
PP--QYPV-GSAGPTQNGFQANQ----VAAYPAQSTYPA-PTFPPSAGYPPEHGLQGQQN
FRPTP-------HYPGQMPHPPPQNALFPEPSDSHASHQKPRQTSLADLEQKVPTNYEVI
TT-PTVMSSAPSEPTYSAPAVT--TSYDQYKAPEPPRPSDRSSVSPSPAPAYSSESLYTN
LEQNIPRNYVMIDDISELTKESTPSAVESQKPEPRPQV-SEGRHTKD-KSDLTEPGGPSV
PCCYSKGEE-SEEDVYDPHSADHRGKGSYHRSSESNGRMPGSG---GSSSYYYGDSDYRH
SSRPEKHGSSTGGPKHSSKNLAPAVISSKRSKHRKQGIEQKISKFSPIEEARDVESDLAS
CPTTPSVSG-SMSSRGKTFQDEITYGLKKNVYEQQKYYGVSSRDLIEEDDRAYSSR---S
RSSVSYGSE-RSSHDMSSRGKSYERE------------------RESMERLQKASSKPSS
LSMSQSRGRPPMRSQASEEESPISPLGRSMGGPRSSGGPLPPGAGDSCSPFCSS-HSLPD
VQEHI-KDVPRTHSYKHEEGYNLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-ESR
SERLRHHGGHSSS--SSSSQKRPSVKHTYHDYD-EPPEEDLWLHDDGPQGRHS-SKEHRH
HGDYGRHSSGS-SSRHQGE-------------------EPSRRVSKPHPRDSGRHEGRPH
SQPSPIP---ALSXR-----SQPSYP-------SSQSEYSQPSRQSAAYHHPPEPKKAQR
PM---QSGPSA----QPHKS------EPQQTRQPPSGPSQQPLPPQSS------------
------RAASRQPP--PQQQQMSHGTQPT-----QSQ--TQQMP--------SQARLQ--
---QQQQPA------SRGPA--AGQQ-----A--G------------KSVPGHTPSAGAQ
PAGPLKADQLDSSKPTAKVQQQ-----------QQQQGRVPHAQPQ-GATTAGTKMGAKT
GGVPPASGAPTGQPGADGDSVFSKILPGGAAEQAGKLTE---------------------
-------------------------------------

---------MGNEASLEGGAGDG-PLPPGGSGP----------GPGAGKPPSAPA----G
GGQLPASGGA-------RATAGP-----PGPGPG----PG--------------------
--AGPGTVSRRLDPKEPLGSQRAASPTPKQPS---APAPSRESPQETR-AQGPAGQEADG
PR RTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLP SSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPVHSPAKQPL
GKPEQEKS-WGPG----GP-------------------------QPGPHQAE--------
---TARATSVPGP-AQAAAPLEVGRVSPQPPL-PIKRSTAEPRPPAGEAPAKSATTAPSG
PGAAEPT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADPQGQAAPSKGPPKIVFSDASK
QAGPRPPGSGPGSG------PAP--GAKTEPG----AK----------------------
------------TGPG----SGPGALARTGGTTSPKHG-----RAEHQA-VAKAAAKPKT
MPKERA-TCPLCQAEL-NVDSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPL-TLPTSQQPPVGAPHRAAGTAPPKQKGPPGLGQPSGPPPAKASP
LPTKAS---------------------PLPTKASPQAKPLRASEPIRTPS---------S
AQEKKTGVPAKAEPVLKPPPETTLPP---GI--PKAKAGVRRTEPATPVVKAGVP-EAP-
--------------------------------------------------KGGEAEEPVG
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGIV-QQEVEQLDSAGATGPCPPSPSELH
KVGS-SMRPSLEAQGPVPSGE-RRKPRY----GSGEEQKRRPHSLSIMPEAFNSDEELED
ILE--EEDSLEWGRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPSRA-AEL
TDEEFMRRQILEMSAEEDNLEED-DAAP---PRHGPVKHGSQKGSP--RPRPEPSQEQG-
-ALPKRRLPHNATTGYEELLSEGGPAEAAD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPPRLYKSGSEYNLPTFMSLYSPTETPLGSTTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPHGGP-SQPVGP----RGQGSFEYQDTPDHDYG-G
AAQPALEGTPAS--LGAAVYQEILQTSQSIARMHQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSS-ASKEVGITFAQGPGTP-ASAAAAPCPAGLPRGYMTPTSP
AGSERSPLLSSTGHSYGQSPTTANYGSQXXXXPQAPR--DLAAWTAREKP-SVSDGESGT
PQTSRGY-YFAGSSPPLSPSSPSESPTFS-GKL--G----PRATAEFSTQTPSPTPA-DM
PRSPGAPSPAPTVAQGTQTPHRPSTPHLVRQQSPQDAPFMVITLGSDASSQTKMVHASAS
TSPVCSPIETQP--TDHSYSQTTP----QLPPEPPGP-PGFPRA----------------
--ASAGADGPLALYSWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAIKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQVGTAQSVGLKSG-PVPEPGSEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSAPEKSVADV--APPGQSSGPFYSPRDPEPPEAPTY
RAQVVGGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHTHRIGHLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRRGS--GGGGPDLMQY-QPQ-
-PGL-----SAPQGLAPLRPGLLGNPTFPEGHPSPGNLAQYRPTAGQG-TAIRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGVTAVPLASLTRM
PMIAPRVPLGPTGLYRYPVPSRFPTASSVPPAEGPVYLGKPAAARAPGAGGPP-------
----------RPELPAGAAREEPLSTATPA-AVKEAVAAPAPA------PAPAAGQKPPV
DAA-PGGGSGALSRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPGRGPPPA--------ATELAQNGQYWSPLTHA
AFI-AVL--EGPGQPR-EPLLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDV
CEPESGP-EPCVVRRIADSSVQTDDEDGEGRYLLTR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------APAVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPAAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLARDR-GGRDYPPLRGXXXXXXXXXXXXXXXXX
XXXX----X------XXXXXXXXXXXXX----X-XX---------XXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXX----XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXX
XXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHYTS
LEQNVPRNYVMIDDISELTKDSASTAPDSQKLEPLGPS-SSGRPGKE-PGEPGVLEGPTL
PCCYTRGEEESEEDSYDPRGKSGH-----HRSVESNGRL--------ASTHYYSDSDYRH
GARGEKYSPGPVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--SAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPVEEDDRVYSGSSR-S
RVASAYSGEKLSSHDVSGRAKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRPRPPMRSQASEEESPVSPLGRPH----PAGGT-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAHKCEEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHGYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHVRDLSRHEARPH
PQPSPAPTVQKK--------GQPGY--------PSSGEYSQPSRVPSAYHHASESKKGS-
RQAHSGPAAL------QPKPEPQL--QP-QGRQAAPGPQQSQPPPSRQTPSATASRQPQT
QQ-----------------QQQGLGLQP----LQQAPSQARLQEQG--------------
QPAARGPAPAA-SQP-AKPQ-PGPSTATGPQP--------SGP-----------------
----PRAEQANGSK-GTA--------------KAPQQGRLPQAQPPPGPGPA--------
------------------------------------------------------------
-------------------------------------

------------------------------------------PGSSAGKESACNA----G
D--P----------------SSI-----PGSKRSPGEGKGYPLQYSWASLVAQMVKNGLE
FITILLLVPRRLDPKEPLGSQRAASPTPKQPS---ATTPGRESPREPR-AQGPEGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------GLSPAHSPAKQPL
GKPEQERA-RGPG----GP-------------------------QPGPRQAE--------
---TARATSVPGP-APAAAPPEVGKVSPQPSL-PIKPSTAEPRPPAGEAPAKSATAAPSG
PGAAEPT-QEGLTGKLFGLGASLLTQASTLMSA-QPEVDSQGQPAPSKGPPKIVFSDASK
EAGPRPPGSGPG--------PGPATGAKTEP-----------------------------
---------------G----SGPRAQARTGGTTSPKHG-----RTEHQAA-SKAAAKPKT
TPKERA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPLP-LPTSQQPPAGAPHHTAGTAPPKQKGPQGLSQPSGPPPAKATP
LPTKAS---------------------PLPTKASPHAKPARASEPSRTPS---------S
AQEKKTGVPAKAEPVPKPPPETTLPP---GT--PKAKAGVRRTEPTTPITK-AVP-EAP-
--------------------------------------------------KGGETEEPGG
KPYSQDLSRSPQSLSDTGYSSDGISSSQSEITGIV-RQEMEHLDSAGVTGPRPPSPSELH
KVGS-SMRPSLEAQGPAPSGE-RSRPPS----GSAEEQKRRPRSLSIMPEAFNSDEELEE
ILEE-EEDSTEWGRRGEQQDAAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-ADL
TDEEFMRRQILEMSAEEDNLEED-EAAP---AGPGLAKHASQKGGP----QPRPESSQEP
GALPKRRLPHNATTGYEELLSEGGPAEDVDGTAGALQGGLRRFKTIELNSTGSYSHELDM
GPGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEAPE-GAPSRLYKSGSEYNLPTFMSLYSPTETPLGSATTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGGRGPHSGP-PQPTAP----RAQGSFEYQDSPDRDYGG-
VAQPAAEGTPAG--LGAAVYQEILQTSQSIARMHQASSRDLAFAEDKK--------KEKQ
FLDAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFATSS--TSDSSGGRVIPDVRVTQ-HF
AKEPQDP-VKLHSTPASPSS-TSKEVGIGFAQGLGAS-ASMAVTPGPAGLPRGYMAPTSP
AASERSPSPSFTGHGYGQSPATANYGSQTEELPQAPRGPAVSGRAAREKPLGVSEGESGP
PQTSRGYPYFVSSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPTPASDT
PRSPGAPAPTPTVAQGTQTPHRPSTPRLVWQQPSQDAPFMVITLASDASSQTKMVHASAS
TSPVCSPVDTQP--TTHSYSQTTPPSGSQ-PPEPPGP-PGFPRA----------------
--PSAGADGPLAVYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAIKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPRETKFARYNLSNQVAPLARRDVLITQVGPAQSVGLKSG-PVPEPGTEP
HRAAPTELRSHA---LPGARKPHTVVVQVGEGAAGTVSTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGSFRTAPSAPERSVAEV--APHGQSSGPFYSPRDPEPPEPPTY
RAQVIGGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAHRFGQLFQGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLTHPLPMRRYSSVSNIYSDHRYGP
RGDAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSGG--GGPDLMQY---QP
QPGL-----SAPQGLAPLRPGLLGNPTFPEGQGSPGNLAQYRPTAGQA-AAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYPPGGVAAVPLASLTRM
PVIAPRIPLGPTGLYRYPVPSRFPTPASVPPTEGPVYLGKPAAAKAPGTGGPS-------
----------RPELPAGAAREEPLSTAPPAAA-KETGA----------APALGAGQKPLG
EA-TPGGGGGALGRPGLEKEDALPEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTLKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKPPFPMAC-EAPGRGPPPA--------VPELAQNGQYWPPLTHA
AFI-AV--PEGSGQPR-EPMLHRGLPSSASDMSLQTEEPWEGGRSGGLKKRHSMPRLRDV
CEPESAP-EPCGVRRIADSSVQTDEEDGEGRYLLTR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSAA--------APTTRATSSVGIQTISDCSVQ
TEPDQLSRVSPAIHITAVTDPKVEIVRYISAPEKTGRGESLACQTEPEGQ-AQGVAGPQL
MGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSAFRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFPLYQHQGGLGSQVSAPPPNGLVRKVKRTLPSPPPE
EAHLPLAGQAAPPQLYAASLLQRGLVGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-SGRDYPPLRGLSEHRDYLSDSELNQLR
LQGC----A------TAAGQYAEIPVTAA---AAAP---------ATPSGSAAFQPPRFP
PPVPLYPA-GSAGPTQNGFAAHQ----APTYPGPSTYPS-PALPPSASYPAEPGLPSQQA
FRPPG-------HYAAQTPLPTTQTTLFPAPADSRAPHQKPRQTSLADLEQKVSTNYEVI
ASPVVAMSSAPSETSYSGPGPTASSSYEQGKVPELPRASDRGGVSLSPAPIYSSDSHYTS
LEQTVPRNYVMIDDISELTKDSASTAPESQRLEPLGPS-SSGRPAKE-PGEPGILEGSAL
PCCYTRGEEESEEDSYEPRGKSGH-----HRGVESNGRP--------ASTHYYSDSDYRH
GTRADKYSPGPAGPKHPSKSLAPAAVPSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPS--SAVSSSLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDPAEEDDRVYGGSSR-S
RGAPAYSGEKLSSHDFGGRAKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRPRPPMRSQASEEESPVSPLGRPR----PAGGP-LPP-GDTCPPFCSS-HSMPD
VQEHV-KEGPRSHSYKRDEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHASE-------------------EPSRRAAKPHVRDVGRHEARPH
PQPSPAQAVQKK--------GQPGY--------PSSAEYSQPSRAQSAYHHSSESKKGS-
RQAHPGPVAL------QPKLES--QPQP-QGRQAAPGPQPSQPPPSRQMPSATASRQPQT
QPQPQQGLGLQ-----------------P---PQQAPSQARLQQQG--------------
QPAARGPASAA-SQPAGKPQ-AGPPTATGPQP--------SG------------------
---PPRAEQANSSK-GTA--------------KAPQQGRPPQAQPPPGPG---VKA---G
AKPGGTPGAPAGQPGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGEG-PLPPGGSGL------GP--GPGAGKPPSALA----G
GGQLPVAGAA-------RAAGPPTPGLGPVPGPGP----G--------------------
--PGPGSVPRRLDPKEPLGSQRTTSPTPKQAS---ATAPGRESPRETR-AQGPSGQEAES
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSAPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQERSPRGPG----AT-------------------------QSGPRQAE--------
---VARATPVPGP-TQATAPPEVGRVSPQPPL-STKPSTAEPRPPAGEAQGKSATTVPSG
LGAGEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPSPSKGPPKIVFSDASK
EAGPRPPGSGPGPG------PTP--GAKTEPG----AR----------------------
------------TGPG----SGPGALAKTGGTASPKHG-----RAEHQA-ASKAAAKPKT
MPKERAAACPLCQAEL-NVGSRGPANYNTCTACKLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPAPL-PLPTPQQPPAGVPHRAAGAAPLKQKGPQGLGQPSGSLPAKASP
QATKASPQAT-------KASPQATKASPQTTKASPQAKPLRATEPSKTSI---------S
AQEKKTATPAKAEPVPKPPPETTVPP---GT--PKAKSGVKRTDPATPVVK-PVP-EAP-
--------------------------------------------------KGGEAEEPVP
KPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVV-QQEVEQLDSAGVTGPRPPSPSELH
KVGS-SLRPSLEAQAVAPSAE-WSKPPRSS-SSAVEDQKRRPHSLSIMPEAFDSDEELGD
ILEE--DDSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA--DM
TDEEFMRRQILEMSAEEDNLEED-DTAV---SGRGLAKHSAQKASA--RPRPESSQE---
---PKRRLPHNATTGYEELLSEAGPAEPTD-GSGALQGGLRRFKTIELNSTGSYGHELDL
GQGPDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAETLD-GGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEDMMRKAEMLQ-RQQGQVAGARGPHGGP-SQPTGP----RSQGSFEYQDTQDHDYGGR
ASQPVAESTPAG--LGAAVYEEILQTSQSIAWMRQASSRDLGFTEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTST--SSDSSGGRVIPDVRVTQ-HF
AKEPQDP-LKLHSSPVSSTL-ASKEVGMTFSQGPGSP-ATTAS------PTRGYMTPTSP
AGSERSPSTSSTIHSYGQPPNTANYGSQTEELPHAPSGPPGSGRAPREKPLSGGDSEVGA
PQSSRGYSYFTGSSPPISPSTPSESPTFSPGKL--G----PRATAEFSTQTPSLTLSSDI
PRSPGP--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPIMVITLASDASSQTRMVHASAS
TSPLCSPTDSQP--TSHSYSQTTPPSASQMPSEPAGP-PVFPRA----------------
--PSAGTDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVSGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPREAKFARYNLPNQVTPLARRDILITQMGTAQGVGLKPG-PVPEPGAEP
HRATPAELRSHA---PPGTRKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPAPSAPDKSVTDT--ALPGQSSGPFYSPRDPEPPEPLTF
RTQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGPGRDSAVD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPLRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGSG--SGGPDLVQY-QPQH
GPGL-----SAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQA-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYVSGGVTAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAP-RFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPELPAGVAREEPFSTTAP-AVIKEAPVAPAPGPAPAPAPAPPPAQKPAG
EAA-AGSGSGVLSRPASEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQLQLEEQKQRQKAPFPATC-EAPSRGPPPA--------ATELAQNGQYWPPLTHA
AFI-AVAGTEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEAGRS-GIKKRHSMPRLRDA
CEPESGP-DPSTVRRIADSSVQTDDEEGEGRYLVTR-RRRTRRSADCSVQTDDEDNADWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTT--------AATARAMSSVGIQTISDCSVQ
TEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
IGPTAISPYLPGIQIVTPGAL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKQFIADSTLRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQV-PSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDYPASA----A-VP---------ATPSGPTAFQQPRFP
PAAPQYTA-GSSGPTQNGFPAHQ----APTYTGPSTYPA-PTYPPGTGYPAEPGLPSQPA
FHPTG-------HYAAPTPMPTTQSAPFPVQADSRAAHQKPRQTSLADLEQKVPTNYEVI
GSPAVTMSSAPPETGYSGPAV-SG-SYEQGKAPEHPRGSDRSSVSQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTPTALESQRLEPLGPGGVSGRPGKD-PGEPAVLEGPTL
PCCYGRGEEESEEDSYDPRGKSGH-----HRSMESNGRP---------STHYYGDSDYRH
GARADKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGSSSR-S
RMASAYSGEKLSSHDYSSRGKGYERE------------------RDTAERLQKAGSKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PAGGA-LPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYMLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHTVSS----SQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHTSAKEHRH
HSDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDMGRHEARPH
PQASPAPAMQKK--------GQPGY--------PSSADYSQSSRAPSAYHHASESKKGS-
RQAHTGPSAL------QPKADTQAQPQM-QGRQVAPGPQQSQPPSSRQTPSGTTSRQPQT
QQQQQ-----------QQQQQQGLGQQA----PQQAPSQARLQPQS--------------
QPTTRGAAPAA-SQPAGKPQ-PGPTTAPGPQP--------AGP-----------------
----PRAEQASSSKPPAA--------------KAPQQGRAPQAQTTPGPGPAGAKP---G
ARPGGTPGAPAGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------SVSRRLDPKEPLGSQRAASPTPKQAP---GAVPGHEGARETG-AQGPAGQEAGG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHSKVCNQCGFNPNPHLTQVQEWLCLNCQMQRA LGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHAPAKPPL
GKPEQERP-RGPG----GP-------------------------QPGPRPAE--------
---TAKATTVPGP-AQAAAPPERGKVSPQPPH-PVKPSTAEPRPPAGEAPGRSATAVPPG
PGAAEQA-QEGLTGKLFGLGASLLTQASTLMSV-QPEADAQGQPAPSKGPPKIVFSDASK
EAGPR PPGSGPGPG------PAA--GAKAEPA----AR----------------------
------------AGAA----SGPGAPARTGGTPSPKHG-----RAEQQA-VPKAAAKPKA
MPK DRP-TCPLCQAEL-NVGSKGPANYNTCTACKLQVCNLCGFNPT-HLVEKSEWLCLNC
QTKRLLEGSLGEPAPCP-PPASPQPPAGAPHRAAGTAPPKQKGPQGPGQPSGPLPAKASP
L----------------------------PTKASPQAKPLRASEPSRTPS---------G
AQEKKTGPPAKAEPVPKPPPETALPP---GT--PKAKAGARRTEPATPAVK-AAP-EAP-
--------------------------------------------------KGGEAE----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------VRRPLRKMREVEQ-QRI
RSTVRKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPARLYKSGSEYSLPTFMSLYSPTEPPAGSSGIPSAGRPLKSAEE
AYEEMMRKAELLQQRQQGQVAGGRGPQGGP-SQPTGP----RAQGSFEFQEAPDRDYS-R
AAPLPAEGTPAG--LGAAMYEETLQTSQSLARGRQASSRDLAFAEDKK--------KEKQ
FLNAESAYVDPMKQNGGPLTPGTSPTQLAAPVPFSTSTSTSSDGSGGRVIPDVRVTQ-HF
AKEPQDP-RKLHSSPASPSP-APQEASTSFPQGPGAPAT----------TARGYGTLASP
AGSERSPSPSATAHGYGQSPTTANYGSQTEEMPQAPSGPA----AAREKPLRVSDGKGGP
APPSQGYAYFPGSSPPLSPSSPSESPTFSPGKP--G----PRATAEFSTQTPSLAPASDM
PRSPGAPTPSPMVAQGTQTPHGPGAPRLAWQQSPREAPFMVITLASAASSQTRMVHASAS
TSPV-SPTDTQP--TPHGYSQTTPLSASPLPSEPPGP-PGFPRA----------------
--ASAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALEPGPGRQSTAVQPLVINLNAQEQTQAFIGTATTVSI
TVASSVLLAQQKQPVVYGDPFQSRLDFGQGTGSPVCLAQVRQVEQAVQTAPYRGGPRG--
----------RPREAKVARYNLPNQVAPLARRDVLITQMGTAQSTGLKAG-PVPEL----
-----------------GARKPHTVLVQMAEGAAGTVTTLLPEE-PAGAVDLTGMRPESQ
LACCDVSTPPS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------A-----------------------------
------------------------------------------------------------
------------------------------AAQREERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVVC-DGPGRGPPPA--------ATELAQNGQYWPPLTHA
AFI-ALAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEPWEAGRS-GLRKRHSMPRLRDT
YEAEPGP-EPSPVRRIADSSVQTDDEDGEGRYFLSR-RRRTRRSADCSVQTDEEDNAEWE
QPVRRRRPRLSRHSDSGSDSKHDAVASSSTA---------APARATSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGGAGPQL
VGPAAISPYLPGIQIVTPGPL----------GRFEKKKPDPLELGYQAHLPPESLSQL-V
SGQPPKSPQVLYSPVSPLSPHRLLDAPFASSERLSKAHVSPQKHFAADGALRQQTLPRPV
KTLQRSLSDPKPLSPTAEESAKERFSLYQLQGGLGSQVSALPPNGLVRKVKRTLPSPPPE
EAHLPLAGQP-PPQLYAASLLQRGLPAA---VPAKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYAPLRGLGEHRDYLSDSELNQLR
LQGC----A------TP-GQYADFPIAA----A-AP---------ATPSGPAAFQQPRLP
APAPQYSA-GSAGPTPNGFPAHQ----APAYPGPSTYPA-PAFPPGTSYPAEPGLQSQQA
FRPTG-------HYAAQTPMPTTQSALYPVPADSRAPHPKPRQTSLADLEQKVPTNYEVI
ASPAVAMSSAPSETSYSGPVI-SS-SYEQSKTPELPRASDRSS--TGPAPTYPSDSHYAS
LEQNVPRNYVMIDDISELTKVSTSTALDSQRLELLGPSG-GGRPGKE-PGEPGALEGPTL
PCCYARGEEESEEDAYDPRGKSGP-----HRGMESDGRA--------ASTHYYGDSDYRQ
GARADKYGPGPTGPKHPSKSLAPAAIS-KRSKHRKQGMEQKVSKFSPIEEARDVESDLAS
YPP--AAGSSGLASRGRRFQDEITYGLKKNVYEQQRHYGVASRDAAEEDDRMYSGSSR-A
RGPAAYGGEKLSSHDVGSRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PTGDA-LPP-GDTCPQFCSS-HSMPD
VQEHV-RNGPRAHTYKREEGYLLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAASS----SQKRGPARHSYHDYD-EPPEEGLWPHEEGGPGRHAVAKEHRH
HGDHGRHS-----GRHAGE-------------------EPGRRAAKPHARDLGRHEARPA
PQPSPAPATQKK--------GQPGY--------PSSAEYTQPPRVPSAYHHASDSKKGS-
RQA--------------PQPKPEPQPQP-QGRQAPPGPQPSQQPAARQTPSAAAAAAARA
PQPQP------------QPQLQGPGP--Q---PPQQTPQARTQQQG--------------
QPAARGPAAAT-SQPAGKPQ-PGPAATAGSQP--------AGA-----------------
----PRTEQTTASK-GAA--------------KAAQQGRPPQAQPPPGPGPAGMKA---G
ARPGGTPGAPAGQPGAEGDSVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------VSRRLDPKEPPGSQRAASPTPKQAS---ATAPGSESPREPR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHSKVCNQCGFNPNPFSPSVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLHSP---------ALSPAHSPAKQPL
GKPEQERSRGPG-----GP-------------------------QPGPRQPETA------
-----RATSVPGP-APAAAPPEVGRVSPQPPL-PTKPSTAEPRPPAGEAPAKSATTVPSG
LGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPDADAQGQPAPSKGPPKIVFSDASK
EAGPRPLGSGPGPG------PAP--GAKTEPG----AK----------------------
------------TGPS----SGPGALAKTGGTSSPKHG-----RAEHQAA-AKAAAKPKA
TPKEKA-TCPLCQAEL-NVGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTEWLCLNP
-TKRLLEGSLGEPTPLPVP-TPQQPPAGAPPRAAGTSPLKQKGPQGL--------GQP--
-------------------SGPPAKAS--RPKASPQAKSLLASEFSKAPS---------S
AQEKKKGLPIKAEPVPKPPAYTAPSP---GT--PKVKSGVRRTXXXXXXXX-XXX-XXX-
---------------------------------------------------XXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXX-XXXXXX
XXXX-XXXXXXXXXXXX---XXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX---XXXXXXXXXX--XXXXXXXXX---
--XXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X--XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXVSFSTA-----TSDSSGGRVFPDVRVTQ-HF
AKEPQDP-LKLHSSPASPSP-ASKEVAMSFPQGPGTP-ATTAVATGPAGLPRGYVAPTSP
AA-SERSPSPSTSHGYGQGPATANYGSQTEELPQAPSGPAVGRRASRDKPP--SDSEGGP
PQPSRSYSYFASSSPPLSPSSPSEGPTFSPSKR--G----PRATAEFSTQTPSPAPASDK
PRSPVAPSSTPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLGSDASSQTRMVHASAS
TSPLCSPTDTQP--TAHSYSQTTPPSAAQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAIKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQPKQPVVYGDPFQSRLDFGQGAGSPVCLAQVKQVEQAVQTAPYRGGPRG--
----------RPRETKFARYNLPNQVAPLARRDILITQMDSAQSVGLKPG-PVPEPGAEP
HRASAPELRSHA---MPGARKPHAVVVQMGEGAAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKFLFGSSCTGTFHPALNMPEKSVAEA--PLPGPSGGPFYGPRDAEPPEL-AY
RAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXX-----XXXXXXXXX-XXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXPRPPGPYRYPASRLP-LAPSAPPAEGPVYLGKPAAAQAPGAGGVP-------
----------RPELPAGAVREEPPSTTTPAAV---------KEAAAAPAPALLAGQKPPG
DA-APGGGSGALGRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREKQ-LLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKVPFPTAC-EAPGRG--------PVPAPTELAQNGQYWPPLTHA
AFI-AVAGPEGPGQPR-ESLLHRGLPSSASDMSLQTEEAWEAGRS-GIKKRHSMPRLRDA
CEPESAP-EPGAVRRIADSSVQTDDEDGEGRYILSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLSRHSDSGSDSKHEATTSSSVA--------TAAMRAMSSVGIQTISDCSVQ
TEPDPLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPAAISPYLPGIQIVTPGPL----------GRFDKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFAADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX------XXXXXXXXXXXXXX---XXXXXXXX-----XXXXXXXXX---XXX
XX--XXX---XXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXX-X--XXX-XXX
XXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX--XXXXXXXXXXX--XXXXXXXXXXXXXX-X-XXXXXXX--XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX-XXXX-XXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXYPSPAASSSLVSRVRKFQDEITYGLKKNVCEQRRHFGMSGRDTAEEDDRMYGASSR-S
RAASAYGGEKLSSHDYGGRGKGYERD------------------REAAERLQKAGPKPSS
LSMAHGRPRPPMRSQASEEESPVSPLGRPR----PAG--GALPPGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYVLDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDWFR-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLHSP---------ALSPAHSPAKQPL
GKPEQEKS-GGPA----GP-------------------------SPGPHQAE--------
---AARATSVPGR-AQADVPPEVGRASPQPPQ-PTKPSTAEPRPPAGEALAKSATTVPSG
SGAAEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEPDPQGQPALSKGPPKIVFSDASK
ETGPRHPSSGPGLG------PAP--GAKTEPG----AR----------------------
------------TGPG----PGPGAQARTGGTPSPKHG-----RAEQQA-IPKATAKPKT
VPKERA-ACPLCQAEL-NVGSKGPANY-TCTTCKLQVCNLCGFNT-PHLVEXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XX-----X---XXX--------XXXXXXXXXXXXXXXXXXXXXXXXXX---------X
XXXXXXXXXXXXXXXX-----XXX-----XX--XXXXXXXXXXXXXXXXXXXXXX-XXX-
---XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX-X----------XXXXXXXXXX
XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX-----------XX
XXXX-XXXXXXXXXXX----X-XXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------X-XXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXX---XXXXXXXX--XXXXX--XXXXXX-XX-X-
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLDL
DPGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPARLYKSGSEYNLPTFMSLYSPTETPAGSTSAPGSGRPLKSAEE
AYEEMMREAELLQ-RQQGRAASGRGSHDGP-SQPVGP----RGQGSFQYQDSAEHNYGGA
T-QTAWE-GSAG--LGAVVYWEILQTSQSIARMRQASXXXXXXXXXXX--------XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX--X-XXXXXXXXXXX--X----XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQEPFFVITLRVKSFILDRTVHASPL
TSAGCSLTDSQP--THLSYSQTTPPSASQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSIPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPAPGCQSTAVQPLVINLNAQEQTHTFLSTATTVSI
TMASSVLMAQQKQPVVYGDPFQSRLDFGQGTGSPVCLAQAKQVEQAVQTAPYRGGPRG--
----------RPRETKFARYNLPNQVAPLARGDVLITQMGPTQNVGLKSG-PVPESGTDP
HRATPPELRSHA---LPGARKPHTVVVQMGEGAAGTVTTLLPEE-PAGALDLTGIRPESQ
PACCDMVYKLPFGSSCTGTFHPTPSAPEKSMADAV-GPPGQSGGPFYSSRDPEPPEPPSY
RAQGVMGPGTQEEQRPYPQGLPGRLYSSMSDTNLAEAGLSFHVQRLGQLFHGPGRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAAGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRRGSS---GGPDLMQY-QAQP
GPG--------------LRPGLLGNPTFPEGHPSPGNLAQYRPTAGQA-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRS-GMYRPYASGGVAAVPLTSLARM
PMIAPRVPLGPPGMYRYPAPGRFPAAPSVPPADGPVYLGKPATAKAPGAGGPA-------
----------RPELPAGAAREEPLSTTTPAA-VKEAP---AP------APAQLTGPKPPG
EA-APGVISGALSRPGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAG-EAPXXXXXXX--------XXXXXXXXXXXXXXXXX
XXX-XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXX-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDSGQWE
QPARRRRSRLSRHSDSGSDSKHEASSA------------TAALRAMSSVGIQTISDCSVQ
TEPDQLPRASPAIRITAATDPKVEIIRYISAPEKTGRGESLACQTEPDGQ-PQGVVGPQL
AGPAAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSAQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERVSLYQQQGGLGSQVSALPPNDRVRKVKRTLXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXKDR-TGRDYLRLRGLGQHRDYLSDSELNQLR
PQSC----A------T-AGQYADFPVTAS--------------------VPTALLQPQFP
PPAPQNAA-SSGGPTQNGFPAHQ----APTYPGPSTYPA-PAFPPGTSYPADPSMPSQQA
FRPTG-------HYAAQTPVSTTQSTLYPTPADSRAPHQKPSQTTLADLEQKVPTNYEVI
ASPVVATSAAPSETSYSGPAVS--SSYEPGRAPDLARASDRSGVSLGPAPSYTPDSHYTS
LEQNTPRNYVMIDDISELTKDSASAASESQRLEPMGPSG-SGRPAKE-PGESGVLEGPTL
PCFYSRGEEESEEDSYDPRGKSGH-----HRGVESNGRP--------PTTHYYGDSDYRH
GARAEKYGPGPAGPKQPSKSLAPAAVPSKRSKHRKQGLEQKVSKFSPIEEAKDVESDLAS
YPS--PAVSSSLSSRGRKFQEEVTYGLKKNVREQQRYYGVSSRDPVEEGDRAHNGSSR-S
RVAAAYSGEKLSSHDFSGRSKGYERE------------------REAVERHPKGGPKPSS
LGTAHSRARPPMRSQASEEESPVSPLGRPR----PAGGT-IPP-GDTCPQFCSS-HSMPD
VQEHV-KDGPRTHAYKREEGYILDDPHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRLRHHGGHAGSS---SSQKRSPARHSYHDYD-ELPEEGAWPHEEGGPSRHASAKEHRH
HSEHGRHS-----SRHTGE-------------------EPGRRVAKPHVRDVGRHEARPH
PQSSPAPAMQKK--------GQAGY--------PSSAEYSQPSRVPSAYHHASDSKKGS-
RQAHSGPAAL------QPKPEPQPQP---QGRQAAPGPQQSQPPPSRQTPSTTTSRQPQM
QQQQ-----------------QSLGPP-H---PQHPPSQARLQQQXX-------XXXXXX
XXXXXXXXXXXXXXX-------------------------XXX-----------------
----XXXXXXXXXX-XX-------------------------------------------
X--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXTEAVSAF--GKKFSSFW------
-------------------------------------

--------------------------------------------PGAGKPPSAPA----G
GGQLPAAGAA-------RSTAVP---PVPG--PGPGPGPG--------------------
--PGPGSTSRRLDPKETLGSQRTASPTPKQAS---ATTPGQESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVTTS-----AWQRALGWHENHA-----------
------PKVV-----------------------AP----------RSQ------------
----------------------------------------Q---------------R---
----------------------------------CLPQ---------PCPPAHSPAKQPL
GKPEVRPA-RAT------------------------------------------------
--------SVRGALPKQLPLPEVGRVSPQSPLNPPKPSQLSPGPCQERPSQKCHWQCPLG
WCREQNPGGPSLVKALRPRRITGLTQASTLMSV-HLKADTQGSLPPARGHPKIVFSDASK
EAAQKPLGLGPGPG------QHL--S-QTEPG----AR----------------------
------------T---GPGFWTLEALPKTGGTTSPKHG-----KSQKLKAANRGLLQAKD
HAEGKG-HNAHCAKPSSMWAARAQPTYNTCTDL--------------QGSKKTEWLCLNC
QTKRLLEGSLGEPTPLPPPTSQ-QPPVGAPHRASGASPLKQKGSQGLSQPSGPLPAKASP
LST---------------------KASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRKAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDAVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGDP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGS-SQPTGP----RGLGSFEYQDTADRDYG-R
AAQPAAEGTPTS--LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSRGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLLRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDNGTCQ--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------CL-----------------------
-------------------------------------------------------HLPTP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGDAVGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAAREEPLPTTTPA-AIKEAAGAPAP--------APLAGQKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESGA-EPCVVRRIADSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTAVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPAPQYSA-GSAGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FRPTG-------HYAGQTPMPTTQSTLFPVPTDSHAPLQKPHQTSLADLEQKVPTNYEVI
ASPVVAMSSAPSETIYSGSAV-SS-GYEQGKVPEVPRAGERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------AGTHYYADSDYRH
GARAEKYDPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTLEDDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPGGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEDGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQSQL-QGRQAAPGPQQSQSPSSRQMPSGAASRQPQP
QQQQQQ--------QQQQQQQQGLGLQP----P------------H--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPARQPGADGESMFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MR-GRG----QAEG
PRRTLQVDPHGQRAGRSPSASPERGSTPTSPYSLPQIAPLPSSTLCPICKTTELTSAPSQ
PNFNACTQCHSKVCNQCGFNPNPHLTEVKEWLCLNCQMQRALGMDM---TTA--------
------PRS------------------------------------KSQ------------
------------------------------------------------------------
--------------------------------QQLHSP---------SPSPSHSPAKLPA
G-------------------------Q----EKTP-APTQPS-ARPGTAATAVPPPEPPK
AQSAAPQREQHGQ-PKAAAPPEAARASPQHQQ-AK-PSSSEQRKALGDPKP---AAPAPG
AGAAEQP-QEGLTGKLFGFGASLLTQASTLMS-VQP-------EAP------------AP
SPQ--ASGKVPPKI--------VFS-----------------------------------
------------DAS------------KEAGPKA--GGAQGRVGAAKAS-KAEPGVKPKE
VPKARV-LCPLCKAEI-NVGSAEPPNYNACTSCRQQVCNMCGFNPAPHLVEKNEWLCLNC
QTQRLLEGSLADPAPMPLP-APKQPTSGSPRHQPTAATQRAAAPAEPAAPP---------
---------------------------K--QQP-SPARSLWAPEQSRAPS---------P
APEKKPPVPAEEKPLPKAAPEPSVPVPKGKSVSPKPEGESKEGRAAP---------EA--
-------------------------------------------------QRAKELED-AG
KPYPPDLSRSPQSLSDTGYSSDGISSSQSEITGLV-QQEEEKLSGTGLAGQSPPSPSELT
KLES-SMRPLLEVRGT-PAEPSK-GSE----TREEQRQRQRPRYLSITPEAFDSDEELED
ILEE-DEDSLEWENQREQRESVESSDEFGSKLRHDYVEDSSEGGFSPVPGRPKGRE-EVA
-DEEFMRRQILEMSAEEDNLEEEEE------EGYGRSKYSVQK------AEAEKGKEP--
-SPAKRRLPHGPGGLYKEERKELEAAESE--DMSTTQGGLRRFKTIELNSTTGYGREMEV
SQEADAGLEREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSISSLEEDSDS
SPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
P--SIDSEAESFD-AVTSKLYKSGSEYNLPTFMSLYSPTEKVES--VQPA-SKPLKSAEE
AYEEMMRKAEMMQK-QQVQQAQQDVSYG-STYQQVGY-RSTEGQNGFQYQYADEYGYDSG
PTRSSQPDYSSSLSKPGAVYEEILQTSQSIARMHQSSSFDLALEKGDKKKGQEEPYQEKH
FLNAESAYAELMKQNGGPLTPGTSPTQLSAPVSFST------S-EGSKVVPDVRVTQ-HF
AKEGQDL-AKLQSTPSAPSP-TSKPITAPYTYSKGTS-AVTMAAASPASTPRIYSSAE--
-------AASTPARSYSPAKSTISYGSQTEDITRSKVGVETSVQTAREKLQAVSDGKPP-
--PAKTYSFFKSSSPPLSPTSPTQSPTHAAPRAAAPSGPTAKSTAEFSTQTQSPLLAYDV
PTTTGPSASSPMVAQGTQTPHRAGSPRLTRQQSSQDAPFMLITLAADAASQTKPPSS--S
ASPVSSPTRISRQVIAHGYGQEPEQPLATFIRAQHV--K-DPAQKVPVT-----------
----SGPDGITGLYSWGALPAENISLCRISSIPGTSRVEPGPKVPSSSAVDLRTALKSAP
IIITDQGMDLTSLATEARKYCLTLDQIPSRQSTAIQPLIINLNAQEQPHAIIAASSTTSL
AIASPMLISQPKQPVVYGDPFQSRMDFGQGAGSPVCLAQVKQVEQGVQTGAGRASGTAGP
APTSKPEPPA-PPQAKFSRYSLPSQM---VKKDVLITQTSVAHSVSGLQQPFQQEQGSEL
YRAVPVELKTQSPLLALGGKKSQVMMVQVEDVAAGPVTKVLKEEPPANVLDLTGVKAESQ
VACCDVVYKFPFGSSCTGAFNPTSKVPEKKAADT--VPSRKASGPLYGSREPEMPETFPY
REQP--APALYEENKFYPTGAFGRLYSSMSDTNLSEIGMNYYPPKGDQPFHE----AAVD
LSTMKHSYSIGFAEGGYLGQGLQYGSFSDLRQPADLLGHPLPMRRYSSASNIYSDYRYSP
RGDLASFQESSLAHYSATTAREISRMCAALNSMDHQYGARHA-----NGPDTMSYG-PGG
GGLP-----AQPGGAAAPKPSGMFNPSVPETRQGFSGLAQYNV-PGVRLGAVRQMFPSSA
TVRAADGMIYSTINTPIASTLPITTQPASVLRPMLR--GLYRPYGPPGMAAVPLASLARV
PVVAPRVPLAPQGLYRYPAPSRLPASS---LMETPVYLGKAVSAAPGTGPAAKAPAAPA-
------TGVQRAEVSGAAPRTE----P------------------------PAAGSKEGG
QA-APAPKL--ASESVQREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERE
RAELQRHREKEQLLVQRELQELQCIKQQVLQQQQEERHAQLALQREQLAQQRLQLEHIHQ
LQHQLQQQLEEQK-RQKTIFPAAG-AEPTSRPPEGPA----EVPRGPMHNGHGWTPAGQV
LP----GGPEGAGGPR-YPAPQRPLSSSASDMSLQAEESWEPGRG--IKKRNSMPRLRDA
YEKET-------VRKTADSSVQTDEEDGEERYMLSR-RRRSRRSTDCSVQTDEEDSGEWE
QPVRRRRSRPSRHADASTEGKADS---T--------------ARGVASVGIQTISDCSVQ
TEPDQLLRVSPSIHITT-HDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIVVPQL
TVPTTITPYSTNMQMVSTGPLDPHAVRQQTLGKFEKKKPDPLEIGYQSHLPADSLSQL-V
TRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFT-DSAQRQQTLPRPI
KTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPGTQVGTLQSSPLARKVKRTLPSPPPE
EPHVALGSPA-TQQLYLGSLAPKAPAAAP---VTKASLLKELDRDLKLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLLKDR-GTRDHPYLRGLADRRDYLSDSELHSLR
LATYDSTGLRP----APTAQYPDFTAASYGA------YPY-----AAPPGPPAFPATRPQ
PP--QFPT-ASTT--QDGLPPAP----LPAFASPATFPA-PG-----TAYPELSAPAQPG
FRPQN-PYQAQGTFAGTASVPAAQPALYQSPSD---AHQKPRQTSLAELEQKIPTNYEVI
SAATSSSAVPD--VTLGAAAVS--SSYEQYKAPEA-RLADRTSVTQGPSASFSSESLYTS
LEQNIPRNYVMIEDISELTKESPAV--DGQKVEPVGTG-ANGRHGKE-KSELLDAEGPSR
PCCYSKAEEESEEDIYDHHGPDHRGKNSYHRE--SNGRVSGSS---AGSSYYYGDSEYRH
SSRADKHGSGMALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSGRT-
-RSSGYGLEKSSGRDTGGRSKSF--E------------------REGVERSQKGSSKPSS
LGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSMGGPGPQSAGDPCSQFCSS-HSLPD
VQEHI-KDVPRNHSYKHEEGYGMDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-EAR
SERVRHYGGHS------SSQKRPPAKHTYHDY-DEPPDEDPWQHDDYPQH-----REHRH
HGDYGRHA------------------------ASSRHDEQPRRSAKQHPRESGRHEPRGH
TTPAAAKKAQQPEPRASAPYG------------PGASEYAPPSRH-----HGAEPQKVPK
TPQPHGAPS-------PAQKP--------E----PSAPA--Q------------------
-------QAAGR------QPQ--AGQQAA-----------RQQPAA------RQGAQ---
--------------------PAGTAQPRAQGP--AAARPAQQ-------QPG--------
-------TGQPTGKAAAT--------------LHAQPGGHPA--PQ-VS---PGLLRPLA
AAGEGLGTGACAAPGAHGRG---------------------HPY--APDSFGVWSLAPAV
LGGCPREAKCTRRGGPEGCSAMPTRRARADRHPLPRS

-------MGNEPAWDGGAGDGPL-PPGGAGPGP----GPGPGPSPGAGKPPSAPA----G
GGQLPAAGAARSTA--VPPVPGP----------GPGPGPG--------------------
--PGPGSTSRRLDPKESLGSQRAASPTPKQAS---ATTPGQESPRETR-AQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKSEQERS-RGPG----GL-------------------------QPGSHQGE--------
---MARATSVPEP-AQAAAPPEVGRVSPQPPQ-PTKPSTAEPRPPAGEAPAKSATAVPTG
LGATEQT-QEGLTGKLFGLGASLLTQASTLMSV-QPEADTQGQPAPSKGSPKIVFSDASK
EAGPKPLGLGPGPG------PAP--GAKTEPG----AR----------------------
------------T---GPGS-GPGALPKTGGTTSPKHG-----RAEHQAASKAAA-KPKT
MPKERA-TCPLCQAEL-NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC
QTKRLLEGSLGEPTPVLPPTSQ-QPPVGAPHRASGASPLKQKGSQGLGQPSGPLPAKASP
LPTK---------------------ASPLPTKASPQAKPLRASEPSKTPS---------S
AQEKKTGVPTKAEPMPKPPPETTPTP---GT--PKVKSGVRRAEPATPVVK-AVP-EAP-
--------------------------------------------------KGGEAEDLVG
KPYSQDMSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPHPPSPSEIH
KVGS-SMRPLLQAQGLAPSGE-RSKPLSS---STGEEQKQRPHSLSITPEAFDSDEELED
ILEE-DEDSVEWRRRREKQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARA-AEL
TDEEFMRRQILEMSAEEDNLEED-DTAT---SGRGLAKHGTQKGGP--RPRPEPSQEPA-
-ALPKRRLPHNATTGYEELLPEGGPAEATD-GSGALQGGLRRFKTIELNSTGSYSHELDL
GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQGQAAGARGPHGGP-SQPTSP----RGLGSFEYQDTADRDYG-R
AAQPVAEGTPAS--LGAAMYEEILQTSQSIVRMRQASSRDLAFAEDKK--------KEKQ
FLNAESAYMDPMKQNGGPLTPGTSPTQLTAPVSFSTP--TSSDSSGGRVIPDVRVTQ-HF
AKETQDP-LKLHSSPASPSL-TSKEVGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPASP
AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPIGLAAAGQAAREKPLSASDGEGGT
PQPSRAYSYVASSSPPLSPSSPSESPTFSPGKL--G----PRATAEFSTQTPSPAPASDM
PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS
TSPLCSPTEIQP--TTHGYSQTTPPSVSQLPPEPPGP-PGFPRA----------------
--PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
TMASSVLMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPG-PVPELGAEP
HRATPAELRSHA---LPGARKPHTVVVQMGEGTAGTVTTLLPEE-PAGALDLTGMRPESQ
LACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADA--APPGQSSGPFYGPRDPEPPEPPTY
RAQGAVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRESAMD
LSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGP
RGEAIGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHGIGG--GGPDLVQY-QPQH
GPGL-----SAPQSLAPLRPGLLGNPTFPEGHPSPGNFAQYGPAAGQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPYASGGITAVPLTSLTRV
PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKASGAGGPP-------
----------RPEIPVGAVREEPLPTTTPA-AIKEAAGAPAP--------APLAGRKPPV
DA-APGGGSGALSRSGLEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPAAC-EAPGRGPPLA--------AAELAQNGQYWPPLTHA
AFI-AMAGPEGPGQPR-EPVLHRGLPSSASDMSLQTEEQWEASRG-GIKKRHSMPRLRDA
CEPESAA-EPCMVRRITDSSVQTDDEDGEGRYLLSR-RRRARRSADCSVQTDDEDSAEWE
QPVRRRRSRLPRHSDSGSDSKHDATASSSS--------AAATVRAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIIRYISAPEKTGRGESLACQTEPDGQ-AQGVAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPPESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE
EAHLPLAGQA-SPQLYAASLLQRGLTGPTSVPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRDYPPLRGLGEHRDYLSDSELNQLR
LQGC----T------TPAGQYVDFPATAT---A--P---------AAPSGPTAFQQPRFQ
PPTPQYSA-GSGGPTQNGFPAHQ----APTYPGPNTYPA-PAFPPGTSYPAEPGLPNQQA
FHPTG-------HYAGQTPMPTTQSTLFPVPADSRAPLQKPHQTSLADLEQKVPTNYEVI
TSPVVAMSSAPSETSYSGSAV-SS-SYEQGKVPEVPRASERGSASQSPAPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDSASTAPDSQRLEPLGPG-SSGRPGKE-LGEPGVLEGPTL
PCCYARGEEESEEDSYDPRGKGGH-----LRSMESNGRP--------ASSHYYGDSDYRH
GARAEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--PAVSSSLVSRGRKFQDEITYGLKKNVYEQQRYYGMSTRDTVEEDDRIYGGSSR-S
RAPSAYSGEKLSSHDFSGRVKGYERE------------------REAVERLQKAGPKPSS
LSMAHSRARPPMRSQASEEESPVSPLGRPR----PAGGP-LPPSGDTCPQFCSS-HSMPD
VQEHV-KDGPRAHAYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS---SSQKRGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRH
HGDHGRHS-----GRHTGE-------------------EPGRRAAKPHARDLGRHEARPH
SQPSSAPAMPKK--------GQPGY--------PSSAEYSQPSRAPSAYHHASDSKKGS-
RQAHSGPAAL------QSKAEPQAQPQL-QGRQAAPGPQQSQSPSSRQMPSGAQQQQ-QQ
-----------------QQQQQGLGLQP----PQQAPTQARLQQQS--------------
QPTARGSAPAA-SQPAGKPQ-PGPTTATGPQP--------AGP-----------------
----PRAEQTNGSK-GTA--------------KAPQQGRAPQAQPTPGPGPAGVKA---G
ARPGGTPGAPASQPGADGESVFSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

---------MGNEASLEGGAGDG-PLSPGGAG------------PSSGRPPSAP----SG
GGQLPAAAVA-------TRATSGP----PGPGPGPGPGPG--------------------
--PGLGPRPDRLDPKEPSGSQRAASPTPKQAS---ATAPSRESSRETR-PQGPAGQEADG
PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ
PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA-----------
------PRS------------------------------------KSQ------------
----------------------------------------Q---------------Q---
----------------------------------LHSP---------ALSPAHSPAKQPL
GKPEQEQS-RGPG----AP-------------------------QLGSRQAE--------
---TFRATSVLGP-AQASALPEVEKVSPQPSF-PTKPSTAEHRPPVGETPAKSATTMPCG
LGDTEQT-QEGLTGKLFGLGASLLTQHG--------------------------------
------------------------------------------------------------
-------------------------------------------KVEHQA-APKTAAKPKT
MPKEKA-TCPLCQAEL-NMGSKGPANYNTCTTCKLQVCNLCGFNPTPHLVEKTDWLCLNC
QTKRLLEGSLGEQSPL-PLPTSQQPPIGVPHRAAGSAPLKSKGTQGLGQPSGPLPAKASP
QPTKASPQPT-------K-------ASPLSTKASPQAKPFKASESGKTPI---------S
AQERKTGVPAKAEPIPKPPPETTLPP---GT--PKVKSGMKKIERASPAVK-AVP-EAS-
--------------------------------------------------KSGEAEEPMG
KSYSQDLSRSPQSLSDTGYSSDGISSSQSEITGVV-QQEVEQLDSAGVTGPCPPSPSELH
KVGS-SMQPLLEAQAVAPSAE-WSKLPCR---ITSEEQKQRPHSLSIMPEAFDSDEELED
ILEE-DEDSLEWGHQQEQRDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPLRA-AEL
TDEEFMRQQILEMSAEEDNLEED-DTAA---SGHGLAKHGTQKGSSGTRPRPESGQE---
---PARRLPHNATTGYEELLTEGGPTESTDSGGGVLQGGLRRFKTIELNSSGSYSHELDL
GQGPDASLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDS
SPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ-QRI
RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
PSPSLDSEAEALD-SGPSRLYKSGSEYNLPTFMSLYSPTEMPLGSSTPPSSGRPLKSAEE
AYEEMMRKAELLQ-RQQSQVGGGHGPHGGP-SQPTDP----RSQGSFEYQKAPDHDYG-K
TAQPVPEGTAAS--LGTAVYQEILQTSQSIARMQQASSQDVAFPEDKK--------PEKQ
FLNADSAYMDPMKQNGGPLTPGTSPTQLAAPVSFTTSTSSD-SSGGRVI-PDVRVTQ-HF
AKEPQDP-LKLHSSPAFPSSG-SKEVGTSFSQGP-GTPAITA------V-APWYMTPTIP
AASESTPSLSSTTYSYGQSPSTANYGSQTEELPKASSGPAAGSRAAREKALSRTDGEAGP
PHVSRGYSYFTGSSPPLSPSSPSESPTFSTAKL--G----PRATVEFSTQTPSPTPSLDM
PWSPGTPTSTSMVAQGTQTPHRPSTPHLVWQQTSHEAPFMVITLASDASSQTGVVHASAS
TSPLCSPTDSQP--TPRSYSQTMPPSVSQLPSE----PPDFPRA----------------
--PSAGVEGPLALYSWGTLPAENISLCRISSVPGTSRVEPGPRPPGSAVVDLRTAVKPTP
IILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHAFLGTATTVSI
TMASSVLMAQQKQPMVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRSGSRG--
----------RPREAKFARYNLPNQVAPLARRDVLITQMGTTQSISLKPG-PVSEPSAEP
HRAIPAELRAHA---LPSARKPHAVVVQMGEGTAGTVTTLLPEE-PASALDLTGMRPESQ
LACCDMVYKFPFGSSCTGTFHPTPSAPAKSMADT--ALPGQSSGPLYSSRDPETSEPPTY
P-QGIVGPRPHEEQRPYPQGLPGRLYSSMSDTNLAEVGVNYQAHRLGHLFQGPRRDSAMD
LSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLIHPLPMRRYSSVSNIYSDHRFGP
RGEAGGFQEASLAQYSATTAREISRMCAALNSMD-QYGGRHASG--GTGPDLVQY-QPQH
GPGL-----SAPQGLDPLRPGLLGNPTFPEGHPSPRNLAQYAPVASQG-TAVRQLLPSTA
TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRS-GIYRPYVSGGATAVPLTSLTRV
PMIAPRVPLGPAGLYRYPAPSRFPISSSVPPAEGPVYLGKPA-AKAPGSGPPA-------
----------RPELPAGAAREEPQSTAPPA-VVKESVAAA--------ASAPLPGQKPPG
DGAAAGGGSVVLGRPGHEKEEASQEERQRKQQEQLLQLERERVELEKLRQMRLQEELERE
RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQ
LQQQLQQQLEEQKQRQKAPFPVAC-EAPGRGPPPA--------ASELAQNGQYWPPLTHT
AFL-AVAGPEGPGQSR-EPMLHRSLPSSASDMSLQTEEPWEAGRS-GIKKRHSMPRLRDA
CEPESAP-EPCVVRRIADSSVQTDDEDGEGRYLLTR-RRRTRRSTDCSVQTDDEDNAEWE
QPVRRRRSRLSRHSDSGSDSKHDATASSSTA--------ASTARAMSSVGIQTISDCSVQ
TEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGHGESLACQTEPDGQ-VQGMAGPQL
VGPTAISPYLPGIQIVTPGPL----------GRFEKKKPDPLEIGYQAHLPLESLSQL-V
SRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTTDSALRQQTLPRPM
KTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLARKVKRTLPSPPPE
EAHLPLAGQA-PPQLYAASLLQRGLVGPTTIPATKASLLRELDRDLRLVEHESTKLRKKQ
AELDEEEKEIDAKLKYLELGITQRKESLAKDR-GGRECSPLRSLGAHRDYLSDSELNQLR
LQGC----T------TPAGQYSGFPASA----A-AP---------ATTSAPTAFQQPRFP
PPAPQYTA-GNIGPTQNELLAHQ----APTYSGPSMYPT-PAFPPSSTYPTEPGLPNQQA
FCPSG-------HYAAPTPMPTTQSTLMPIPADSRA-SQKPRQTSLADLEQKVPTNYEVI
TTPVVAMSSAPSETSYSGPAV-SS-SYEQGKTPELPRASDRGNVSQSPVPTYPSDSHYTS
LEQNVPRNYVMIDDISELTKDS--TVPDSQRLEPLGPG-SSGRPGKE-PGEPGVLEGPTL
PCCYTRGEEESEEDSYDSRGKAGH----HHRSMESNGRP--------TSSHYYSDSDYRH
GARVEKYGPGPVGPKHPSKSLAPAAVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLAS
YPP--SAVSSNLASRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGGSSR-S
RIASAYSGEKLSSHDFSGRGKGYERE------------------REAVERLQKAGSKPSS
LSMAHGRARPPMRSQASEEESPVSPLGRPR----PIGGT-LPP-GDTCAQFCSS-HSMPD
VQEHV-KDGPRAHSYKREEGYILDDSHCVVSDS---EAYHLGQEE---TDWFDKPR-DAR
SDRFRHHGGHAVSS----SQKRGPARHSYHDYD-EPPEEGLWSHDEVGPGRHAPAKEHRH
HSEHGRHT-----GRHAGE-------------------EPGRRTAKSHVRDSGRHEGRPH
SQPSSAQAMLKK--------GQPGY--------PSPTDYSQPSRAPTAYHHTSDSKKGS-
RQAHSGPVVL------QPKPEPQAL--P-QGRQAAPGLQQSQPPPSRQMASGAALRQPQM
QQQQQQQ--------QQQQQQPGLGQQP----PQQALSQARPQQQS--------------
QPAARGPASGA-SQPTGKPQ-PGSMTATGSQP--------AGP-----------------
----PRAEQADGSK-VTT--------------KPPQQGRAPQAQPTPGPGPAGMKA---G
ARPGGPPGAAPGQPGAEGESVLSKILPGGAAEQAGKLTEAVSAF--GKKFSSFW------
-------------------------------------

Query Results

"ENSGT00620000087961_1"

ENSGT00620000087961_1