Query Results 

------------MEASRRFPEAEA-----L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHNQLFEHQKEGIAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEDRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQVTDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYT
CDLSVKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLLSTHHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GK----GTGSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADIGPN-LDQLKDDEILRHCK-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEEPSASSPQYACDFNLFLEDS-ADN
RQNFSSQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSSI---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLM
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQDK-------A-AEATSDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------------------------------------SYL----IYRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEELAEN-------GD-DEFTDVCN
SGLLLYRDLHNQLFEHQK

PF00270 // ENSGT00590000083118_0_Domain_1 (139, 302)

EGIAFLYSLYREGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLISTWVKEFVKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFNGKEFMWDYVILDEAHKIKTSSTKSATCARAIPARNRLLLTGTPIQNN
L

ENSGT00590000083118_0_Linker_1_2 (302, 536)

QELWSLFDFACQGSLLGTLKTFKMEYETPITRAREKDATPG-KALGFKISENLMTIIKP
YFLRRTKEEVQKKKSSNPEIRLSEETPGVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSTRACHLLNLGTVKFSAQDGIEEEDS
SGVDP--IDQIPDDTLMGESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKLLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQIGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELRELFTIEDLQNSVTQLQLQTLHAAQRRSDKNLDEHIAYLHSLGIAGISDHDLIYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNS---TERQRTGYEETWQRAIAF
PSQTKKKLNKEVSKPQSRPSPFITTHYT-------------QEEDISYQMASVTIDDPPE
ESEKQD-LSSIMMNITVQQD-------------GRDPHESAFDADSVTTSSKGSG----S
VEEVWTDSLLGMAKGFATENEAVQKEALQEGPKQETLPEN-------PLGSSAYLLSK--
-ADLGPN-VDLLQDDEILHHCG-------AGSITPIRNENQNT----RSNTSAVEIAD--
DLSASHSAPQD----AQASE---AKL--------EEEPLASSPQYACDFNLFLEDS-ADN
RESPSGQSLELVEQ----------ENSLCGFAAHSRAESVR-----------SKECVTLD
FSEKDNEPEEVVVNV-KTRSKARR-IVSDDEEEEE-DSCKGTWSP---SPFSTSPFQFSS
VKQFDASTPKNDVSLPGNFFSPKGPDSENKSIN-----PRRSLASRRSLVNVVLDYVEDM
EERLGNS---------GEAKVAEEDPEEGAEESSDEASACTEEDPSGEMLSSESKPSRLS
ASKLSA-----SALATSPGDP-E--PLS-GEQVVASPQDK-------A-AEAADDYETLV
MRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLNLYKQLNNT

----------------------MEAY---RGLAEAETLSSEQAAR----YLRYVKEAKEA
TKNGDLEEALKLFSFAKDIFPNEKLMSRIQKLQEALEELEEH-------ED-DEFTDVCN
SGLLLYRELYNQLFEHQKEGVAFLYSLY

PF00176 // ENSGT00590000083118_0_Domain_1 (149, 379)

KDKRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHALLIMPTNLISMWVKEFSKWTPGMRVKTFHGPSKDERTRSLNRVQQRNGVVITTYQ
MLINNWQQLSSCNGQVFVWDYVILDEAHKIKSSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIVRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQKTKSNIP

ENSGT00590000083118_0_Linker_1_2 (379, 503)

EVRPTEKNSGVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSTRVCHLLHLGTAKISGQDGNEE-DS
SDVDA--IAHVTDDTLMEESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLIDLLKRLRDEGHQTLVFSQSRQILNIIERLLRNK
HFKILRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKGSLIRQTTGDKKNPYRYF
NKQELRELFTVEDLQNSATQLQLQSLHAAQRRSDKTLDEHITYLHSLGIAGISDHDLIYT
RDLSVKEEL---DVIEESQYIQQRVQKAQFLVEFESQNT---VEKQRTGNEGAWPTAPLF
FSQTKKKCP-ELKKPQHWPSSLTTTHPT-------------QEGVISFQMANLSIED---
----QD-FSSVKMHMTMLQD-------------SMHSCENTFHTDSVATLTKEFG----S
VEEIWTASLQGTAKSFAVENEALQKKSLQEEPEQEALQEN-------PLGSFNYLASQSV
KADLAPN--LDLQDDKIFDHYS-------IWPSNPITNENQNT----KSNVSVIEISN--
ELSASHSVLQG----AQANE---AKS--------EGEPVASLPQYACDFNLFLEDS-ADN
TQNLSTQSLEYVEK----------ENSLCGSAANCSAESVH-----------S----NLD
SSKKDNDPEEVVVNV-KNRSKARR-IVSDDEDEDD--SFKGTSSI---SPFSTSLYHFSS
VKQFDASTPKDD-SLPGRFFSPKISDSINKSVN-----PRRSLASRRSLINVVLDHVEDM
EERLDNS----------KAEGTGDDLKEGAEESSDKASEHTE-DPSGERPSAENKSGGLT
VSKPLD-----SSLPTSPGSP---DPLS-AGLVVDSPQDK-------A-MEAANDYETLI
TQGKELKQCGKIQEALNCLVKALDIKSSDPEVMLMTLSLYKQLSNT

----------------------MEAS---IALAEAEALSPEQTTC----YLRYVKQAKEA
TKNGNLEEALKLFNLAKHIFPNAKVLSRIKKIQEALEELADP--------GDDEFTDVCN
CGLLLYRELHDQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 418)

HQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLISMWVKEFVKWTPGMRVKVFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPAKNRILLTGTPIQNN
LQELWSLFNFACQGSLLGTLKTFKMEYENPIIKAREKDATPGEKALGFKMSENLMAIIKP
YFLRRTKEEVQEKKSSNPETRLSEK-PNIDALCDMPSLSEN--DIIWIRLLPLQEXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNERAWPREPVS
SSQTKKKCP-ELNKPEFQPSALITTHDT-------------QEDDISFQMASVIIDDRAE
ESEKQD-FSNINMNISVLQD-------------EN-------DAEFAATPPRRYG----S
VGEICTGSLLEVKESFTTDNEALQKEALQE---------S-------PQESFNDLLNKSV
VTDLGPN-LDQLKDDEILQHYS-------LQTTNPTTKK--NI----KLNTSIIEITD--
DSSASHSALQD----AQANE---AKL--------EEEPLPSSPQYACDFNLFLEDS-VDS
EENPSCHSLEHDEK----------HNSFCSSAVNSRAEFVY----------NNNTCLRLD
FSEKDDELEEVV-NV-KTRHKGRR-ILSDDEDEDN--SFKSIPSR---NPFDTSLFSFSS
VKQFDASTPKNDISPPQRFFSPKIAGSGNKTIN-----SRRSLASRTSLINVVLDHVDDM
EERLDNS---------SEEKS---------------------------------------
------------------------------------------------------------
----------------------------------------------

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 502)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTHHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------------GTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
SQNFSDQSLEHVEK----------EKSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-PDN
RQNFSGQSLEHVEK----------EKSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDVD--DSFKDTSST---NSFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

---------------------------------------------------RLVIDAKEA
AGSGDLEQALQLFQQAAAIRPSEKLRGRIQRLEAALAELAA-----AEEEDDGNFVDVCG
SGLLLYGEMHEKLFQ

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQREGVAFLYRLYREGRPGGILADDMGLGKTIQIIAFLSGMFDSE
LIRHVLLIVPTTLISSWLAEFARWTPGLRVKEFHGTSKIERTRNLEKIQRKNGIVITSYQ
MLINNWKQLASCHGQDFIWDYIILDEAHKIKCPSNKTTKCVYAIPAKHRLLLTGTPLQNN
LQEMWSLFDFACQGSLLGTAKTFRMEYENPITRAREKDATVGEKALGLKISENLMTIIKP
YFLRRTKDDIKKNHTEKSDTPLPED-PHEPSAPVMPSLTRKNDFVVWVYLAPVQEKIYRN
FLCLDHVKELLTTTRSPLAELTVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACTQLDLDGQEYLEQDHGSEA-A
VLSGANKIDHLSDESLIQESGKMLFLLGLLERLREEGHRTLVFSQSRKMLDIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

VLSSR
RFKIMRIDGTVTHLTEREKRINAFQSNKDYSVFLLTTQVGGVGITLTAANRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTLEDTRTSTTQIQLQSLHATQRQTDVQLDEHIAYLHSLEMFGISDHDLIFT
REVTHE---EQAESEEAHQYIQQRVQKAHELVQLESQLRDVRMEEIRNAAEETWSRPPEL
ASQSKKRSP-GLNNITNFVSPPAADKCENDKVIDLTEDMEVQVLDVSSKMTNLTI-DEK-
-----------------------------GEQPNIQESEQNLDLNSIPLSPGLSPLDKET
QI-----------------------LKQKRCSLYHVNSDS-LTEAGNGPSEPSQHSCNQS
VMADDLKRLQD---TEMADRVL--DSFA----VSE-TEKNDVSELALSAS--PPDLSD--
VLPEVHAE-----------VQKYHVLET-----SSEGMSVPSLQDQVDFNLVLEES-EGG
LQDA-SNGERSMEHPE---------------------GENGNSG-NPCHTAEEDPNNSLQ
GSEASEEGSAVLVSG-RK-KHMRR-IVSDSEDEDHSVISLEKEQFDKRSSPLNSPL-HQF
IEGISASTPKNDRSIAKAIFSPKLT------NS-----SNRSTASRRSLINKVVDEVEDI
GEIM---GTTDEEENS--HEEQEGFAEEEA-EECSGESAEPEEEPAGETLNSTGESFHTE
GTQS-EGGETESSQEESTGDA----ELQSDEQLEYCTQESF----------STGNYSTLV
DRGKNLKDSGKLQEALNCFLQALDIKSGDPEIMLMTLNLYRQLAQK

----------------------MEVS---RGFSEAGPLSPEQAAS----YLRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFIDVCN
SGLLLYQELHNQLYEYQKEGVAFLYSLYRDGR

PF00176 // ENSGT00590000083118_0_Domain_1 (153, 373)

KGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISIWLREFVKWTPGMRVKTFHGPSKDERTRNLCRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFLWDYVILDEAHKIKTSSTKSAICARAIPASNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLRTFKMEYENPITRAREKDATPEEKALGFKISENLMAIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 502)

KKSSNPEAQLSEKSPDVGAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGAAKFSVQDEIEGEDS
SDVDH--IDHISDDTLMEESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMVFLMDLLKKLRDEGHQTLVFSQSRRILNIIERLLKNR
HFKILRIDGTITHLVEREKRISLFQQNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKNLDEHIAFLHSLRIAGISDHDLMYT
RDLSVKEEL---DVIKDSHYIQQRVQKAQFLVECESQNTELLMERQKMGNEGIWLREPVY
Q--TKKKHP-EVNKPQPQPSSRLPIYHT-------------QEEEISSLMASVIIDDLPK
EGE-KD-LSRTKMNDTIPQD-------------GRHPCVSTFDDDFVTTLPKGCG----D
VEEIFPDSLSGM---------ALQKEASQEGFMQESEQES-------PLGSFNYLPSKSA
SVDLGPN-LDQLEDDEILHHRN-------PSPANPKTKEYQRP----ESNVSVIKIAD-D
DLAAAHSALQG----AQTNE---AKL--------EEEPLASSAQYACDFNLFLEDS-ADN
GQNLSSQFLEHVEK----------ENSLCGSAANSRAESVH-----------SKACLSVD
LSEEDDEPE-I-VNV-KIRRKARR-IDSDDEGDH---TFKDTSST---NPFNTSPFPFLS
VKQFDASTPKNDISPPGSFFSPKVSESINKSVN-----SRRSLASRRSLINVVLDHVEDM
EERLDNS---------SEANVVEDYLEEGAEESGDEAPEHTKEDPSRETLSSENKSSQLS
ASKPGA-----LAQETSPGDP-E--PLS-GGQLVDSPQDE-------T-VEAVNDYDTLV
LHGKELKECGKIQEALDCLVKALDIKSSDPEVMLMTLSLYKQLNKT

----------------------MEAP---SR

PF00176 // ENSGT00590000083118_0_Domain_1 (32, 454)

LAGAEDLSSEQAAR----YLRYVKEAL-A
AKNGDLQEAFKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XX-XXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
MLINNWEQLSRFNGQEFVWDYVILDEAHKIKTSSTKSAICARIIPASNRILLTGTPVQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMTIIKP
YFLRRTKEEVQKKTSCNEEVRLSVKNPTSDTICEMPSLSRKNDLIIWIRLVPVQEEIYRK
FISLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACHLLNLEAGQFSVENER--EDL
TDTGH--LSQVTDTTLMEESGKMIFLMDLLKKLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLRNR
HFKILRIDGTVSHLVEREKRIDLFQKNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSIVRQTTGDKKNPFRYF
SKQELRELFTVEDLQNSATQLQLQTLHAAQRRSDKKLDDHIAFLYSLGIAGISDHDLMFT
HDVSVKEEL---DVIKDSNYIQKRVQKAQFLVESESQNPELLKERQKS--EATCLVESMF
PHTKVKG-H-HSNRPKPASLPPKASSET-------------EEEEMISQLASVIIDDLPD
TSEKDL----TSLNVSDLQK-------------SRHTCESTSHDYSAATFYERCE-----
CEEVGRDSVFGIAEGFVAESKSQQKEAIGEMAAQKALEVK-------PLRSD--LLRVSV
GGDVETN-LDQLKDGESLHHCS-------PWPMNSATNKNQSE----ELNASVTTKSH--
DFSAPHSALQDALQDVQANE---AKL--------MEKTSAFSPQYACDFNLFLEDS-PDN
RQDFSSRSPLHVKK----------ENSLCGSAASSRAELVQ----------NIE------
SLHLKDDETEVVVNA-KSKRKTRR-ITSDSEDEGA--TCQETVST---NLFSASPFEFSS
AKQFDASTPKSD-SSSGRFFSPKISDSIRKSISDSVRKSRSSLASRRSLINVVLDHVEDM
EESLDNN---------SEGEESVEYLEEGEEENSGQIPEGTE-TPTRESLPSESEASCLT
APKPDD-----PAQEPPCGDP---EPLS-GVQSSDVPQEK-------A-VETADDYDSLV
KRGKELKECGKIQEALNCFVKALDIKSADPEIMLMTLSLYKQLNKS

----------------------------------M-ADPGPEE----ERYRRLVIDAKEA
AGSGDLEQALQLFQEAVTIRPSEKLRGRIQRLEAALAELAV--TAEEEEEDDGNFVDVCG
SGLLLYGEMHAKLFQHQREGVAFLYRLHRE

PF00176 // ENSGT00590000083118_0_Domain_1 (151, 378)

GRPGGILADDMGLGKTIQIIAFLSGMFDSE
LIRHVLLIMPTTLVSSWLAEFARWTPGLRVKEFHGTSKTERTRNLEKIQRKNGIVITSYQ
MLINNWKQLASCHGQDFVWDYIILDEAHKIKCPSNKTTKCVYAIPAKHRLLLTGTPLQNN
LQEMWSLFDFACQGSLLGTAKTFRMEYENPITRAREKDATVGEKALGLKISENLMTIIKP
YFLRRTKDDIKKNHAEK

ENSGT00590000083118_0_Linker_1_2 (378, 502)

SDTPLPED-PREPSAPVMPSLTRKNDFVVWVYLAPVQEKIYRN
FLCLDHVKEVLTTTRSPLAELTVLKKLCDHPRLLSARACTQLDLDGQEYLEQDHESEA-A
VLSGANKIDHLSDETLIQESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMLFLVGLLGRLREEGHRTLVFSQSRKMLDIIERVLSSR
QFKIMRIDGTVTHLTEREKRINAFQSNKDYSVFLLTTQVGGVGITLTAANRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTLEDTRTSTTQIQLQSLHATQRQTDVQLDEHIAYLHSLEMFGISDHDLIFT
REVTHE---EQAESEEAHQYIQQRVQKAHELVQLESQLRDVRMEGIRNAAEEMGSRPPEL
ASQPKKRSP-GLNNMNNFVSPPAADKCENDKVIDLTEDMEVQVLDVSSKMTNLTI-ELGE
EKLAQE-TSGMDIELLT-------SGKKMEQPPSIQDSEQNLDLNIIPLSPELGPPDKET
Q--------------------------QKQCSLYDINSDS-LTETGNSLSGPSQHSSNTS
VMADDPKRLED---TEIADEVL--DSFA----VSE-TEKNDVSELALSVP--LPNLSD--
VLPEVHAE-----------VQKSHVLET-----SLEDASVPSLQDQVDFNLVLEES-EGG
LQDA-SNGERSMEHHSEDEDFQLKAESWCKSPAKTCVSENGNSG-NSCHTAEEDPNNSLP
GSEASEEGSAVLVSG-RR-KHMR--IVSDSEDEDYSVINLKEEQFDKRSSPLNSPL-HQF
IEIISASTPKNDRSIGKATFSPTL-------NS-----SNRSTASRRSLINKVVDEVEDI
GEIM---GTTGEEESS--DEEQEDFAEEEA-EECTGESSEPEEEPAGETLNSTGESFHTE
GTQS-EEDESESSQEESTGDA----ELQSDEQLEYCTQESVSTV--QSSSLPSGNYNTLV
DRGKNLKDNGKLQEALNCFLQALDIKSGDPEIMLMTLNLYRQLAQK

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

PF00176 // ENSGT00590000083118_0_Domain_1 (201, 454)

FVRWTPGMRVKAFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSMNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPAKNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITKAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSNPDIRFSENNPDVDAICQMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARAYCLLNLGGSKFSSQNENEREES
SDVSH--LYQVTDDTLMEESGKMIFLMNLLMRLRDEGHQTLVFSQSRQILNFIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKKR
HFKTLRIDGTITHLLEREKRIKLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQSSATQLQLQSLHAAQRRSDEKLDEHIAYLHSLGIAGISDHDLIFM
HDLSV-EEL---DMIEESQYIQQRVEKAQLLVXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXX-------------XXXXXXXXXXXXIIDDVAE
ETEKQD-LSSMKMNVSDQKD-------------DKHTCENRLDSEFTATLSREGA----D
VEEICTDSLLKLARSFTTDTEALQKEAL---------QES-------SLGSYNGSPGKSL
RADTGPN-LDQPKDDEILHHCN-------LWPTNPITSQNENV----ECNSSIIELAD--
DLSASHITLQD----TQTNE---AKS--------EEEPSASSLQYACDFNLVLEDS-ADN
RQNISSQCLEHSEK----------ENNWCSPEANSRAEFVH----------NKTGRFSLG
FSEKDDESEVLVATAK----RVAK-IVPDGRDVDY--SFEGISST---NPFSTSPFPFSS
VEQFDASTPKKDISPSQTFFSPKIAVSGNKTIN-----SRQSLASRRSLINVVLDHVEDM
EERLDNS---------SEAKSTDDYLEEGAEGISGETSENAEEDLSREKQSSQNKSSWLT
LSNPGA-----SVSETPVDDP-E--SLS-GRQLMASTHDE-------E-VEAASDYETLV
IRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNKT

---------------------------------------------------RYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------ED-DEFTDVCN
SGLLLYRELHN

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 297)

QLFEYQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINMWIKEFAKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSLNSQQFVWDYVILDEAHKIKTSSTKSAICARAIPASNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 536)

IQNN
LQELWSLFDFACQGSLLGTLKTFRMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSNPEVRLDEKNPDADAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGAVKFSVQDENEGEDS
SDVDH--LDKITDDTLMEESGKMIFLMDLLQRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTITHLVEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYT
RDLSDKEEL---DVIEESHYIQQRVQKAQFLVGLESQNTE--MERERAGIEGIWLREPVF
PSQTRKKCP-ALNNSQPRPSRLLTTLHS-------------QEEEISSQMASVIIDDLPE
ESEKQD-LSSMKMNVTVLQD-------------GRHPRESTFDADFVATSPKGCG----S
VGEIWSDSLSGM---------ALQKEASREGPTKEALHDN-------PLGSFNYLLSKSV
RADLGPN-LDQVKDDEILNPWS-------RWPVNPITSENQNT----ESNASVLTIAD-D
DLSASHSALQD----AQATE---AQL--------EEQPLASSPQYVCDFNLFLEDS-ADN
GK-LSSHSLEHVEK----------ENSLCGSAADAGAEFVP-----------SKACLSVD
LSEKDDEAEEEVVNV-KVRSKARR-IVSDGEEEHD--TLKDASIT---NPFNLSPFQFSS
VKQFDASTPKNDISPPGKFFSPKIPDSVNKSIN-----SRRSLASRRSLINVVLDHVEDM
EERLDSS---------SEAKVVGDYLEEGAEESSGEASEWTEEDPSGEMLSSEKKSSRLA
PPEPGA-----LAQEP-SSDP-V--PLS-SGQLVDSPQDR-------A-VEAVNDYETLV
RRGKELKECGNLQEALNCLVKALDIKSADPEVMLMTLSLYKQLNKT

----------------------MEAS---QGLAEVETLSPQLAES----YLRYVQEAKEA
AKNGDLEESLKLFNLAKDIFPTKKVMSRIQKLQEALEQLAED--------DDDEFIDVCS
SGLLLYRELYEKLFEHQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGAILADDMGLGKTVQVIAFLSGMFDAS
LVNHVLLIMPTNLINTWVNEFAKWTPGMRVKTFHGSSKSERTRSLTRIQQRNGVVITTYQ
MLLNNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAVCARAIPASNRLLLTGTPVQNN
LQELWSLFDFACQGSLLGTLKTFKMEYEHPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQM

ENSGT00590000083118_0_Linker_1_2 (373, 505)

KKADNPEARLGEKNPAGEAICETFPLARKNDLIVWIRLLPLQEEIYRK
FVSLEHIKELLMETRSPLAELGVLKKLCDHPRLLSARACRLLNLGTATFSAQDENEQEDV
SNMNS--IDHLTDKTLMQESGKMI

PF00271 // ENSGT00590000083118_0_Domain_2 (505, 615)

FLMSLLERLQDEGHQTLVFSQSIKILNIIERLLKNK
HFKTLRIDGTVTHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
TKQELKELFTVGDLQNSATQMQLQCLHAAQRRSDEKLDEHIAYLHLLGIAGISDHDLMFT
CDLSVKEEL---DMLEDSQYIHQRVQKAQFLVESESQDT---VQRQRSGIEETWLKAQEF
PSQQKKKGT-EFKKPQPQPSRLLS-KPT-------------QVEAVSSQMASITICDQSA
ESEPQE-H-SEVHDDVTSLQ-------------GSHHLNSTFDAGTIASLPQEAE----S
IREVSTDSLLSPAKGFAAENDAMQKKGLQASPGQEAPSEN--------LGSFHYLPRESS
KASLGPN--LDLQDSVVLYHRS------------PTANENQNL----ESDVPMIEISD--
DLSAPPSVLEG----AQAIE---AQLELKED-----DPLKSPPQYVCDFNLFLEDS-ADT
RQNLSSKFLEHVEK----------EQSLQSPAANSRAKSAL--------------TLSLD
SS-KSDEESGVIS-V-KTKSKARR-ILSDDEDEDEEDAFKGS-ST---NSINISPFPFSS
VKQFDASTPQSDSNPSRRFFSPKIPGEVNTSLY-----SRRSLASRRSLINVVLDDVEDI
EERLDNS---------SEEESEPGLSEE---SNEEEALACTEEQPSGATLASGNKSSNLT
MSEPTS-----PAPQSSPCAP---EPSS-SDPMPDPPQDP-------A-VEAGNDYESLV
ARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNI-

----------------------MEAS---QKFAEAEALSPGQVAL----YQSYVKAAKEA
TKNGDLEGALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFTDVCD
SGLLLYRELHDQLFEHQKEGVAFLYNLYRDGR

PF00176 // ENSGT00590000083118_0_Domain_1 (153, 373)

KGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFVKWTPGMRVKTFHGPSKDERTRNLTRIQQRNGVIITTYQ
MLINNWQQLSSFNGQEFVWDYVILDEAHKIKTSSTKSAICARAVPASHRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGYKISENLMAIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNAEVRLSETNADVDATCEMPSFSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGTVKFSAQDGNEGEDS
PDMDH--IDQITDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKILRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNTELLMEQQRARNEG--LREPVF
PSQAKKKCP-KLNNPQPQPSPLITTHHT-------------QEEYITSQMSDLIIDDLPQ
EGEKED-LSSIKTNFTILQD-------------GRHPGKSSFDADSIAVLPKGFG----S
LEETRNDSLSGMTRSFATEKEALQKEASQEGPTQEALQEN-------PLGSFNYLLSKSV
KADPKPN-LDQLKDDEILHHCN-------PWPINSITNENQNT----ESSVSVIEIAD--
DLSVSHGAPQD----AQANE---AKL--------EEEPSVSSPQYVCDFNLFLEDS-ADN
GKNPSSQSLKPVEK----------ENSLHGSAADSRAESVH-----------SKPHLSWD
SSEK-DEPEEVVVNV-KIRSKARR-IISDDEDED--TSFKGTSST---NSFNTSPFQFSS
MKQFDASTPKNDISPPARFFSPQISKSVNKSIN-----PRRSLASRRSLINMALDHVEDM
EEILGNS---------SEAKSAKDHPEEEAEESSGEGSGCTEEDHSGETPSSENKSSQLM
MSQPSA-----LAQETSPGEP-E--PPS-G----GSPQDE-------A-VEAVNDYETLV
MRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNT

-------------------------------------------------FYRYVAQAKEE
ARKGNLEESLQFFKLANEIDPSEKLRNRIKRLEETLAELALA------TEEEDGFVDVCN
SGLTIYGEMHNKLFEHQREGVAFLYSLYRDGRQGGI

PF00270 // ENSGT00590000083118_0_Domain_1 (157, 297)

LADDMGLGKTIQIIAFLSGMFDAE
LVQFVLLVMPTTLVSNWRREFAKWTPGLRVKDFHGTSKTERNRNLERVQRKTGVVITTYQ
MVIYNWQQLSSFNEQEFVWDYIILDEAHKIKSSSTKTTKSMYAIPAKNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 537)

VQNN
LREMWSLFDFACQGSLLGTVKTFKMEYENPITRAREKDATPGEKALGLKISENLMTIIKP
YFLRRTKDDIQKYKSDKVETSLPED-QSKNIAPVMPSFTRKNDFIVWVYLTPIQEEIYRN
FLSLDHVKELLMTTRSPLAELNVLKKLCDHPRLLSARACSQLGLEGGVYTED-KENEG-D
AFSGANKIDHLSDKLLIEESGKLLFLMGLLERLQEEGHKTLIFSQSRKMLDILERI

PF00271 // ENSGT00590000083118_0_Domain_2 (537, 615)

LTHR
HFRTMRIDGTVTHLVERERRIAVFQGKKDYSVFLLTTQVGGVGINLTAASRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELRELFTLEDTQTSATQIQLQSLHATQRKTDLELEEHIAYLHSLEMFGISDHDLMYT
REIAQ----EQAENEEAHQYIQQRVQKAQELVQLESQLKDQLMGRIKNNTEGAWLTQPKS
SSQPKKEWP-GFNT--NYISPPVLAEPANEEVAHLIEDE--DVADVSAGMTSLVIVDSGE
N-PEQD-MSNMDIDESL-------SSKALKQ-SNIHEPEQKLDPNVIPSSFGIRSRANKE
TH----SP------------------------------------------EPSRHS----
----------Q---SISDVHVT--SSLH----SQP-YDENENPELAFPVI--SKSLFN--
VTSEFPSR-----------HQKSHVSEA-----SLDSTSVTSFQYQADFNLVLEES-EDG
QQDV-SKMEKILEY-SENAGFQLKAGNHSSSAMNSWVREHDDDFGS--------------
--------PCN---V-AIRKHARR-MVLDSEEEDNSVIILDENLPEKMSSPLNSPL-CPS
LTGISSSTPKCDRSLIGSTFSP----------R-----GNRSTASRKSLINVVMDQVEDF
EETM---GALSQTENS--DEVQEDLVVEEA-EEHSVESVVPEEEPVGETLDTEGTASYLD
DTESVTSEADETDKEESTGDP----ELLSGEQMDCFSKTTVDS------LRAPDNYDALI
ECGKKLKDNGKLQDALNCFLQALDIKNGDPEVMLITLNLYKQLSQR

MRSVGAGEIQSSVEIPGTKLRVMEAS---RGSVEAAALSPEQAAL----YQRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFTDVCN
SGLLLYRELHNQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 453)

HQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAT
LVSHVLLIMPTNLISTWIKEFVKWTPGMRVKTFHGSSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKTSSTKSAICARAVPARNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKIEYENPIMRAREKDATPGEKALGLKISENLMAIIKS
HFLRRTKEEVQKKSSTPEEIRFSEKNPDGDAICKMPSLSRKNDLIIWIRLRPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPR

ENSGT00590000083118_0_Linker_1_2 (453, 536)

LLSARARHLLSLGSVKFSVQGENEGEDA
SDVDH--IDHVTDDTLMEESGKMIFLIELLRRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRVDGTVTHLVEREKRIHLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENIVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKILDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNTELLVEKQRTGNEGTWLREPLF
PSQTKKKCP-EMNKPQPWPSSHLPTYHI-------------QEEVISSQMASVIIDDLPK
ENENQD-ISNIKMNVTVLQD-------------GSHSLVSTSDADSVAILPKGCG----C
VDEIWTNSS-GM---------AIQKEALREGPTQGTLQKN-------PLGNFNYFLSESV
RDDLGPN-PDQLKDDETLPHCS-------PWPINPMTNENQNT----ESHASVIEIAD-E
EWSASRSALQD----AQVHE---AKL--------EEEPLASSSQYACDFNLFLEDS-ADN
EQNFSSQSLQHAEN----------ENSLCGPAANSKAESER-----------GEVRLSLD
LSETQDDPEVVIGNMKKGRRKARR-ILSDGENEDK--TFQDTPGT---NL-FTSPCQFLP
IKQFDASTPKSDISPPGRFFALKIPDSINKSVN-----ARRSLASRRSLVNVVLDHVEDM
EEGPDNS---------SKAEVAEDYLEEGAEESSGEVSEYTE-DPPDETLPSEHKSSWLT
TREPGA-----LVQEASPGDP-E--PLL-GRQLVDSPQDE-------A-VEAVNDYEALV
IRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLNLYKQLNKT

-------------------------------------------------------MEQKT
P--KTRKRS----SKVHKIQPKEHPTEDVQDAEEKLMSLALDK-----DGDGDEFVDVCQ
SGLMICRELHD

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 296)

KLFEHQKEGVAFLYNLYHKKRQGGILADDMGLGKTIQIIAFLSGMFDAG
LVRSVLLIMPVTLVNNWMREFANWVPGIRVKVFHGTSKKEREQNLEQIQRRTGVLLTSYQ
MVLANWEQLSNLDGQPFVWNYVILDEAHKIKSPSAKTTKSVYGIPAVNRILLTGT

ENSGT00590000083118_0_Linker_1_2 (296, 537)

PVQNN
LRELWALFDFACQGSLLGTAKTFKMEYESPIMKAREKDATLGEKALGLKISQNLMAIIKP
YFLRRSKGEILKLNSERS-VCLTGE-ERDYIALEMPSLPRKNDFIVWVYLAPMQEDIYRN
FLSLDHIKELLMTTRSPLAELTVLKKLCDHPRLLSAQACANLGLEVSEYSEPTDQ----S
TLSMTQDIKRVSDKLLIEESGKLVFLVALLEKLQEEGHQTLVFSQSRKMLDIIEHI

PF00271 // ENSGT00590000083118_0_Domain_2 (537, 615)

LTKR
SFRLMRVDGTVTCLAEREKRVRQFQMDKSYSVFLLTTQVGGVGLTLTSATRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIQQSTGDKKNPYRYF
TQQELRELFTLEDTTSSATQLQLQSLHATQRNSDLELDEHIAYLHTLEMFGISDHDLMYT
CETGQEEEEEEAEDDEAHQYIEHRVKKAQELVQLESQLKDKKYQKSRYL-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------

----------------------MEVS---WGLAEAQVLSPEQAAR----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEALADP-------GD-DEFTDVCS
SGLLLYRELHDQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQKE-VAFLYSLYRDGRKSGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISTWVKEFDKWTPGMRVKTFHGPSKDERTRNLRRIQHRNGVIITTYQ
MLINNWQQLSSLDGQEFVWDYVILDEAHKIKTSSTKSALCARAVPASNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGLKISENLMAIIKP
YFLRRTKEEVQKKRPGDPEVRLSEKNPGVDATNEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACHLLNLEDVTFSVEDEGEDKEA
SDVDH--ISQVTDVTLMKESGKMIFLMDLLERLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTITHLVEREKRINLFQQNKDYSVFLITTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRAHRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQRENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFAIEDFQKSATQLQLQSLHAAQRRSDRRLDEHIAYLHTLGIAGVSDHDLMYT
QDLSAKEEL---DVIEESQYIQQRVQKAQFLVECESQNTELLLERERAAHQGLWRREAEF
PSQTKAKRP-ESKKPQAEPSAPPSARLT-------------WEEEISSQMARVALGDLPE
TGDKAG-LPSIETSVVVPQD-------------ARLPRGTELGADFAEAPPAGSD----S
VEEISTDFSLGVAVP----------------PWGQAPPGS-------PTRSSRLSLSTSA
TADLAPN-VDEVRDVAVSQRWD-------PRAAAPTTQEQQST----RSDASGIDTAATS
DLSAPRGA--------PADV---AAA--------GGGSAASSPQYACDFNLFLEDS-ADS
GRDPSSRSSELVEK----------A---GGSAARVGAEFVR-----------SHARLSAG
LSGDDQEPEEVVT-V-KGGRKTRR-IVSDDEDDGD--SFRSASGT---DSLSTSPFRL-P
VKFFDASTPKSDVSPPGRFFSPLLTDSINKSAK-----SRRSLASRRSVVNLVLDHVEDM
EDGLETS---------AEAQGAAPGPRAGAEGSSGEASDSAGEEPSRETLSPENKSSWPT
APQPAA-----LVVEASPGGSGSPEPPT-AAQAVGGPQGE-------A-ARAARD

PF07719 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YESLV
AHGKALREAGRLQEALSCFVEALDIRSADPEVMLMTLSLYKQLNST

------------MEASGRFPEAEAL-------------SPEQAAH----YLRYVKEAKEA
AKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWLKEFGKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFLWDYVILDEAHKIKTSSTKSAICARAVPASNRLLLTGTPIQNN
LRELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 505)

K-TSNLDVKLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGTVTFSAQDENEGEDS
PDMDH--IDQITDDTLMEESGKMI

PF00271 // ENSGT00590000083118_0_Domain_2 (505, 615)

FLMSLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRNRNEGAWLKEPVF
PSSTKKKCP-KLNKPQPQPLPLISTHHT-------------QEEDISSKMANVVIDDLTE
EGEKQD-LSSIKMNATTLQD-------------GRHPCESRCSADSIATLPKGFG----S
VEELFTNSSLGMEKSFATKNEALQKETLQEGPKQEALQED-------PLGSFNYLPSKST
KADLGPN-LDQLKDDEILHHRN-------PWPIISITNESQNA----ELNVSINEIVD--
DFSASHSVLQD----AQANE---AKL--------KEEASASSPQYACDFNLFLEDS-ADN
RQNLASQSSEHVEK----------GNSLGGSAANSRAGFVH-----------SKTCLGWE
FSEKDDEPEEVVVKA-KIRSKAGR-IVSDDEDED--DSFKDTSNT---NPFNTSLFQFSC
VKKFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLSSRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASECAEEDPSGETQSSENKSSWSI
MSKSSA-----LAQETSLGSP-E--PLS-GEQLVGSPQDK-------A-AEAVNDYETLV
KRGKELKECGKLQEALNCLVKALDIKSADPEVMLLTLSLYKQLNT-

----------------------MEAS---QGLAEVEALSPQLAAS----YLRYVQEAKEA
AKNGDLEEALKLFNLAKDIFPTKKVVSRIQKLQEALEQLAEE----EEEDDDDEFIDVCS
SGLLLYRDLYEKLFEHQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNRVLLIMPTSLINTWVKEFAKWTPGMRVKTFHGSSKDERTRNLTRIQQRNGVIITTYQ
MLINNWQQLASFNGQEFVWDYVILDEAHKIKSASTKSAICARAVPASHRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 504)

TKKADNPEAGLSEKNLGVEAICEMPSLTRKNDFIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARVCHLLNLGTATFSVQDENEQEVA
PDVDS--IHHLTDNALMQESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLVALLERLQDEGHQTLVFSQSRQILNIIERLLRNR
HFKTLRIDGTITHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTVGDLQNSATQMQLQSLHAAQRRSDEKLDEHIAYLHSLDIAGISDHDLMFT
RDLSVKEEL---AMVEDSPYIQQRVQKAQYLVESESQNT---MERQRTGTEEAWLKAYSF
PSQQ-KKGP-ALNKPQPQASRLLT-NPT-------------QVEDISSQMASITIYDQSA
ESEPRD-D-SKAHDVTLLQG-------------DQHHCESAFDAGSVATSPQGTA----S
IGGVWTDSLLGPTKCFAAESEAVQEKALQASPGQEALPEN-------LLGSFNDLPTQSI
KADPGPN--LNLEDSVLSCHCS------------PTANENQNI----ESDVHTIEISD--
VLSASPSALQG----AQASE---AQLEVRPQLELEEGLLESPPQYACDFNLLLEDS-TGT
RQSLSSKFLEHVEK----------ENSLQSPAANSRAESAL--------------NLSLD
SSNKSDEEPEVIS-V-KTRSKARR-ILSDDE--GEEDAFKGPSGT---SSFSISPFQFSS
VKQFHVSTPKNDANPSARFFSPKLPGSVNTSFN-----SRRSLASRKSLINVVLDDMEDM
EERLDES---------SEEESARGHSEE---ESSDEAIACTEEDPSGETQASGNKPSSLT
VPEPTS-----LALESSPCAP---EPLS-SDPLVEPPQDP-------A-VEAANDYETLV
ARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNS

-------------------------------------------------

PF00515 // ENSGT00590000083118_0_Domain_0 (50, 83)

FYSYVKKAKQE
ATSGNLEKAIKFFVKASEIHPS

ENSGT00590000083118_0_Linker_0_1 (83, 136)

DKIHRRIEKLKEALEELDLQ------EDADDDFVDVLN
SGLTIYNELYNKLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQKEGVAFLYSLYRDGRKGGILADDMGLGKTIQVIGFLSGMFDSE
LIKYVLLVMPTTLISNWVKEFQKWTPGLRVAEFHGTSKKERTRNLEKIQRMSGIIITTYQ
MLINNWQQLATYNGREFEWDYIILDEAHKIKTSSTKTAKSCHSIPAKNRILLTGTPIQNN
LREMWALYDFACQGTLLGTSKTFKMEYENPITRAREKDATPGEKALGLKISENLMKIIQP
YFLRRTKSDVQNKKTERTRA------QDTSQGPSMPSLTRKNDFIVWVYLSTIQEDVYRK
FISLDQIKELLMTTRSPLAELNILKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACIQLGLEGDDYHSNEE-----G
DHELVTKFDHLSDEILIEESGKLLLLIDLLHKLKEEGHRTLVFSQSRKMLDMIDR

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

ILQNK
NFKVMRIDGTVA-LPEREKRISIFQSNNNYSVLLLTTQVGGVGLTLTAADRVVIFDPSWN
PATDAQAVDRAYRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQQENVVIYRLITCGTVEEKIYRRQIFKESLIRQTTGDKKNPFRYF
SKQELKELFSLEDTRTSSTQIQLQNMHAAERKTDTRLDEHIAYLHTLQIFGISDHDLVYA
NELSSQED--NEYEDEHGQYIEQRVQKAHELVQMESQLNEQLMDQIRKSTEGAWVRQIST
APEKPKK-T-SLPREKQYSSPPVTVDLTE-----------DDVGEVSCHMTSLIINDSSG
EEDVDLPAAPFSIKPLNGNSHSGDTSHAAEKPLKLENSLQQSHEKI---------FDKQE
E---------------------------------IIVSDSSVIETDDDRNTPSLKG---D
W--SKPSP-----------PVTEHISYSH------------------PAEGEPIPIWH--
VEPEVCKKLRHSFGNRTEEFQQSCVTDTDMNDGLEASLSASKSHLPCDFNLVLDDS-MER
DCSKQDFKEYPLEGEEDEKSFHINEVS-------------------------GTDNNELQ
ASVHTDSEDELEYFV-SKKKTARR-IYSDSEGESSVYVDENEKVFS----P---TS-SPS
VKGITASTPKLNKSISDSLFPLRQS------LG-----RRRSIASRRSLVHVAVEEAADV
NDTIVSSSSE------ESGEEEDEFVTSEAKEADEEESVEPEEEPAGETLPQEEIKSSFD
QE------EDDCSSDESTGE-----DLLPGEQIDYLAQENVNIKGGV--SLNEDP

PF07719 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YVTLV
NRGKQLKDAGKVKEALACFLEALDLKPGDPEIMMITLNLYRQQPQ-

----------------------MEAS---QGLAEVETLNPRLAES----YLRYVQEAKEA
AKNGDLEESLKLFNLAKDIFPTKKVISRIQKLQEALEQLAEE-------DGDDEFTDVCN
SGLVLYRELYEKLFEHQKEGIAFLYSLY

PF00176 // ENSGT00590000083118_0_Domain_1 (149, 373)

KDQRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLINTWVKEFAKWTPGMRVKTFHGSSKDERTRNLTRIQQRSGVIITTYQ
MLINNWKQLASFNDQTFVWDYVILDEAHKIKSASTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQM

ENSGT00590000083118_0_Linker_1_2 (373, 503)

KKADKPEARLSEKNPGVEGICEMPSFTRKNDFIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGTATLSAQDENEQGDT
SDVNS--IDHLTDRVLMEESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLMALLERLQDEGHQTVVFSQSRQILNIIERLLKNK
HFKMLRIDGTITHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQIFKDSLIRQSTGDKKNPFRYF
SKQELRELFTVGDLQNSATQLQLQSLHAAQRRSDEKLDEHIAYLHSLNIAGISDHDLMFT
HELSVKEEL---AMLEESPYIQQRVQKAQLLVEFESQNT---MERQKTGNEETWLKAHAF
SSQRNKKGP-ELNKPRPQPSHLLT-NPT-------------QVEAISSQMASISIGDQSS
ESESQD-P-SKSLDVTLLQG-------------DGHHYESTLDADTGATSPQEAG----S
MGGIWTDSSLGPAECFAAGNEAMQKKASQASPGQEALPEN-------LLGSFNYLPRQSM
KADLGSN--LDLQDS------S------------PTADENQNI----ESDAHVIEISD--
VLSASPSALQG----AQVSE---AQLELEEDL--------SESEYACDFNLLLEDS-TDN
RQNLS-KFLGLVEK----------ENSSQSPAANTRAESAV--------------NRSFD
SLNESDEEPDMIS-V-KTRSKARR-ILSDTE--D-EDTFKGTSST---SSFSTSPYQFSS
VKQFDASSPKDDKSPPGRFFSPKIPDSVNVSLD-----SRRSLASRRSLINVVLDDVEDM
EERLESS---------SE-ESAPGHEEEEEEESSEEASVHTEEDPSEEAQASGNKPSSLT
ESEPRP-----LTPKSSPCSP---EPLS-SDALVDPAQEP-------A-VEAADDYETLV
ARGRELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNA

---------------------------------------------------RLVASAKAA
AADGDLEEALRLFRLAAAIRPSEKLQSRMQRVQEVLAAAEQQQQEE--EDDDEGFVDVCG
SGLLIYGEMHRKLFQ

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 451)

HQREGVAFLYRLHRERKPGGILADDMGLGKTIQVIAFLSGMFDAE
LIQHVLLIMPTTLVSSWLAEFARWTPGLRVKEFHGTSKTERTRNLERVQRKNGIVITSYQ
MLINNWKQLASRHEQEFVWDYIILDEAHKIKCPSNKTTKCVYAIPAHYRILLTGTPVQNN
LREMWSLFDFACQGSLLGTAKTFKMEYENPITRAREKDATPGEKALGLKISENLMSIIKP
YFLRRTKEDIKKYHADKADSPLSED-PSENKAPVMPSLTRKNDFVVWVYLAPVQEEIYRN
FLCLDHVKEVLMMNRSPLAELTILKKLCDH

ENSGT00590000083118_0_Linker_1_2 (451, 537)

PRLLSTRACTQLGLEEEEDSEQDYRMEA-I
MFSGKNKIDHLSDETVIEESGKMQFLVGLLERLREEGHRTLVFSQSRKMLDIIELV

PF00271 // ENSGT00590000083118_0_Domain_2 (537, 615)

LSRR
QFQILRIDGTVTHLTERERRINAFQTNTTYSVFLLTTQVGGVGITLTAASRVVIFDPSWN
PATDAQAVDRAYRIG---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------

------------------------------------------------MFYRYVSKGKQE
ARDGNLEESIRLFRQALAIHPSEKLTKNIKKMEEALASLALD------QEEEDSFVDVCQ
SGLMMYGEMYDKLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 376)

HQREGVAFLYGLYRDGKKGGILADDMGLGKTIQIIAFLSGMFDEE
HIKSVLLIVPTTLISNWTKEFASWTPGLRVKVFHGTCIAERNRNLEWIQRRHGILLTTYQ
MVLNNWQQLASFGNKEFVWDYAILDEAHKIKTPSAKTTKSVHAIPSKNRILLTGTPVQNN
LKELWALFDFACQGSLLGTMKTFRMEYENPITRARAKDATPGEKALGLKISENLMSIIKP
YFLRRSKDELKKTVN

ENSGT00590000083118_0_Linker_1_2 (376, 537)

LEQKSNLPAL-QSKDAAPPMPSLPRKNDFIVWVYLAPIQEEIYRK
FISLDHIKELLMTTRSPLAELNILKKLCDHPRLLSARACSQLGLETSSCYDLDGDENE-A
NDVLHQNIEHLSDQVLIEESGKLLFLVALLDRLQEEGHRTLVFSQSRKMLDIIERI

PF00271 // ENSGT00590000083118_0_Domain_2 (537, 615)

LTRR
RFKLMRIDGTVTHLTEREKRIGMFQKNSEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRAYRIGQKANVVIYRLITCGTVEEKIYRRQVFKDSLIRQSTGEKKNPYRYF
SNQELRELFTLEDPRSSSTQLQLQSLHSSQRKTDTQLDEHIAYLHSLEIFGISDHDLMYT
HETVNE---DEAENEEDHRYIEHRVQKAQELVQLESQLKDQLVESMGNTTEGAWLRETEL
STQPKKKTP-RPPQ--NHVSPAPV-QPTSDG----------VVDLVSSKMASLVIEDVDD
EQILQD-ISNMDVSLS---------KKKEDKPARLQAYEQEHDQRTMSPLPRSNSFSNKS
ED----CRS----------------PRLRESKKQSYHPEF----------SPTSH-----
----DPLALDVDNKSDMDISLAKNEECNSPQLQQN-SDSKRMPSFLAALSLSYEPHAN--
NTSK-CSA-----------VQKSEIML-------EEESFTTPSPYQTDFNLVLDDS-EDG
LQVA-LGEEMSLEE-TENEGFQLQLDSHHSSASHSWAGGNEGNGSLQPRLS---------
--DASMDN-SEISLR-YKKKPIRR-IVSDDEEEQHDSVTELDDSEHEKISA------LNN
IGRICMSTPKANESMASLGFSPRLK------VS-----GRRSTASRRSLANLVMDQVEDM
AEVV---EPESEGPPQ--SSLQESLESEMSKSYSDQEPSELEEEPSGETVDSEDTSSYM-
------------------------------------------------------------
----------------------------------------------

----------------------NSVI---CGIFQIVHISPQLILHYLKRNSLYVKEAKEA
AKNGDLEEALKLFNLAKDIFPNEKVMSRIQKLQEALEELAEE-------EN-DEFTDVCN
SGLLLYRELYNQLFEYQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 375)

KKGGILADDMGLGKTVQIIAFLSGMFDAS
FVKHVLLIMPTSLINTWIKEFARWTPGMRVKTFHGPSKDERTRNLRRIQQRNGIVITTYQ
MLINNWQHLASFNGGEFVWDYVILDEAHKIKSSSTKTAICARIVPARNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKIEYENPIVRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKK

ENSGT00590000083118_0_Linker_1_2 (375, 504)

PSDPEVRPNENTPGVNPICEMPSLSRKNDLIVWIRLVPLQEEIYRK
FTSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARVCGLLNLGNIRFSAQDVNEED-P
SEVHN--IDHITDETLMNESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLNRLRDEGHQTLVFSQSRQILNIIERLLKSK
YFKVLRIDGTVTHLWEREKRIQLFQQNKEYSVFLLTTLVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELRELFTIEDLQNSATQLQLQSLHAAQRRSDEKLDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESQYIQQRVQKAQFLVEFESQNT---MGKQRTENEEAWQRASIL
ASQTKKRGP-GLNKPQHQPSPFRTTHYT-------------QEDDISSQMANISLDDQSQ
ESEPQD-LSSVAVNVTMMQD-------------GSHPYENKFDADSASTLPTGVG----S
AERMWTESSLGTAEVCAIEDEAVQKEALQERPRQAALQES-------PLGSL---LSQSV
RAEAEPGPIRDLQDSEILHSCS-------S-----------CQ----ESNTSIIKISD-D
SLSASHSTLQV----AQVNG---ANT--------KEKSLSSSPQYACDFNLFLEDS-ADN
RQNLSDQSLEHVGK----------EEGPCGSAVNSRAESVH----------HS------S
LSSGKDEAEEVVINV-KTRSKARR-IISDDEDEDD--PFKSTSST---SPFSTSPFEFTS
VKQFDASTPKHDTSQSGRLFSPKMPDSGNKSTT-----SRRSLASRRSLINVVLDHVEDM
EEELGNH---------HEAEDAADDPQG-----ETSCDECTEEDLPSETLPSKDKSSELK
MSEPSS-----PVLQTSSGAT--PEPLS-GEPLVASPQEK-------A-VEATDDYETLV
ARGKELKECGKIQEALNCFVKALDIKSADPEVMLMTLSLYKQLSNT

----------------------MEAS---QGSAEAEALSPGQVAL----YQRYVKEAKEA
TKNGDLEGAFKLFNLAKDIFPNEKVMSRIQKIQEALKELAEH-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGVAFLYNLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 451)

RKGGILADDMGLGKTIQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFVKWTPGMRVKTFHGPSKDERSRNLKRIQQRNGVIITTYQ
MLINNWQQLSSFNGQEFVWDYVILDEAHKIKTSSTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSNAEVRLSETNADVDATCEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDH

ENSGT00590000083118_0_Linker_1_2 (451, 504)

PRLLSARACHLLNLGTVKFSAQDGNEGEDS
PDMDH--IDQITDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKMLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRRSDEKLDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNTELLMEQQRARNEGAWLREPVF
LSQAKKKCP-KSNNPQPQPSPLITTHHT-------------QEEHIISQMSNVIIDDLPE
GGE-KD-LSSIKADFTILQD-------------GRHPGESAFDADSIAILPKGFG----G
LEETRNDSLSGMTGSFATEKEALQKETFQEGPTQEALQEN-------PLGSFNYLLSKSI
KADPKPN-LDQLKDDEILHHSN-------PWAINPLTNENQNT----ESSVSVIEIAD--
DLSVSHGALQD----AQANE---AKL--------EEEPSISSPQYACDFNLFLEDS-ADN
GKNPSSQSLKHVEK----------ENSLCGSAANSRAESVH-----------SKPYLSWD
FCEKDDEPEEVVVNV-KIRSKARR-IVSDGEDED--NSFKGISST---NSFNTSPFQFSS
VKQFDASTPKNDISPPARFFSPQVSNSVNKSIN-----PRRSLASRRSLINMVLDHVEDM
EERLDNS---------SEAKSTKDYLEEEAEESSGEGSGCIEEDASGETLSSENKSSQLT
MSKPSA-----LAQETSAGEP-E--SLS-C----GSPQDK-------A-VEAVNDYETLV
TRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNT

---------------------------------------------------RYVKEAKEA
TKNGDLEEAFKLFSLAKDIFPSEKVMSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHD

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 297)

QLFEHQKEGVAFFYSLYRDGRKGGILADDMGLGKTIQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFVKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWRQLSSFNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPAINRLLLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 536)

IQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRARQKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEIQKKKSSNLEVRISEKNPDVGATCEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACQLLNLGTVKFSALDGNEGEDF
PDMDH--IDQITDETLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKTLRIDGTITHLLEREKRINLFQKNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYT
CDLSAKEEL---DVIEEPHYIQQRVQKAQFLVELESQNAGLLMEQQTTRNEGTWLREPVF
PSQTKKKCP-KFNNPQPQPSPLLTTHHI-------------QE-DISSQMANVIIDDPPE
EGEKDD-LSSIKTNITIPQD-------------GWHPCESTFDADSIATFPKGFE----S
LEETWNDSLLGLSKSFATEKEALPKEALQEGPTQEAPQEE-------PPGNFNYSLTKSI
KADLKPN-LDQLKDDEISHQHN-------PWPINPITNGNQNT----ESNVSVIEITD--
DLSASHSALQD----AQANE---ANL--------EEKLSTSSPQYACDFNLFLEDS-ADN
GKNPPSHSLEHMEK----------TNSLCDSAANSRSEFVP-----------RKTCLSWD
FTEKDDEAEEVIVNV-KIRSKARR-IVSDDEDEDDYDSFKGTSST---KSFHTSPFQFSS
VKQFDASTPKNNISPPGRFFSPIMSNSVNKSIN-----SRRSLASRRSLINMVLEHVEDM
EERLDDS---------SEAKSAKDYPEEEAEESSEEASEHTEEDPSGETLSSENKSSWLT
RAKPSA-----LVQETSLTES-E--PLS-S----DSPQDE-------A-VESVNDYETLI
MRGKELKECGKLQEALNCLVKALDIKSADPEVMLMTLSLYKQL---

----------------------MEAS---QGLAEVETLSPQLAES----YLRYVQEAKEA
AKNGDLEESLKLFNLAKDIFPTKKVMSRIQKLQEALEQLAEE-------EDDDEFIDVCS
SGLLLYRELYEKLFEHQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVNEFAKWTPGMRVKTFHGSSKSERTRSLTRIQQRNGVVITTYQ
MLLNNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAVCARAIPASNRLLLTGTPVQNN
LQELWSLFDFACQGSLLGTLKTFKMEYEHPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 505)

TKKADNPEARLGEKNPAGEAICDMFSLARKNDLIVWIRLLPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACRLLNLGTATFSAQDENEQEDV
SNMNS--IDHLPDKTLIQESGKMI

PF00271 // ENSGT00590000083118_0_Domain_2 (505, 615)

FLMSLLERLQDEGHQTLVFSQSIKILNIIERLLKNK
HFKTLRIDGTVTHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
TKQELKELFTVGDLQKSATQMQLQCLHAAQRRSDEKLDEHIAYLHLLGIAGISDHDLMFT
RDLSVKEEL---DMLEDSQYIHQRVQKAQFLVESESQNT---VQRQTTGIEETWLKAQEF
PSQQKKKGT-EFNKPQPQPSRLLT-KPT-------------QVEAISSQMASITICDQSA
ESEPQE-H-SEVHD-VTSLQ-------------GSHHFNSTSDAGTIASLPQGAE----S
IGEVSTDSLLSPAKGFAAENDAMQKKGLQASPGQEAPSEN--------LGSFHYLPRESS
KASLGPN--LDLQDSVVLYHRS------------PTANENQNL----ESDVPMIEISD--
DLSEPPSALQG----AQAIE---AQLELKED-----DPLKSPPQYACDFNLFLEDS-ADT
RQNLSSKFLEHVEK----------EKSLQSPAANSRAKSAL--------------TLSLD
SSPKSDEESEVIS-V-KTKSKTRR-ILSDDEDEDEEDAFKGS-HT---NSINISPFPFSS
VKQFDASTPQSGSNPSRRFFSPKTPGEVNTSLH-----SRRSLASRRSLINVVLDDVEDM
EERLDNS---------SEEESEPGLSEE---NNEEEALACTEEQPSGATLASGNKSSNLT
MSEPTS-----PAPQSSPCAP---EPSS-SDPMPDPPQDL-------A-VEAGNDYESLV
ARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNI-

----------------------MQNY---QGLVEWESLGTEQAAR----YMRYVKEAKEA
TKSGDLEEALKLFSLAKDIFPNKKLTSRIQKLQEAWEQLEAH-------EE-DEFADVCN
SGLLLYRELYNQLFEHQKEGVAFLYGLYRDGR

PF00176 // ENSGT00590000083118_0_Domain_1 (153, 373)

KGGILADDMGLGKTVQVIAFLSGMFDAS
LVTHVLLLMPTHLISMWVKEFAKWTPGMRVKTFHGPSKDERSRSLHRVRQRTGVLITTYQ
MLINNWQQLSSFNGQEFVWDYVILDEAHKIKSSSTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYEIPIIRGREKDATSEEKALGLKMSENLMEIIKP
CFLRRTKEEIQK

ENSGT00590000083118_0_Linker_1_2 (373, 503)

KRSNTPEVRPTEKNPGVDAICKMPSLSRKNDLIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACRLLHLGTVRISAQDGNEE-DS
SDVDS--IAHVTDDTLLEESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLINLLKRLREEGHQTLVFSQSRQILNIIERLLKNK
HFKILRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGAGLTLTAATRVVIFDPSWN
PATDAQAVDRIYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDQKNPFRYF
SKQDLRELFTVEDLQNSATQLQLQSLHAAQRSSDKNLDEHITYLQTLGIAGISDHDLIYT
HDLSVKEEL---DVIEDSQYIQQRVQKAQFLVEFESQNT---VEKQRTGNEGAWPIASLF
PSETKKKCP-ELKKLKPWPLPLITTHLT-------------QEGDISFQMANVSIDD---
----QD-LSNAKMNVTVLQD-------------IIHPCENTLNTDSVATLPKEFG----G
IEEIWTAPLLGTARSFVVENEALQKQALQEEPEQEALQEK-------PLGSFNYLAIQAV
KGDLAPT--LELQEDEILYHCN-------PWPSNPITNKSQNT----KMGASVIEISD--
ESSASRGAVED----TQASE---AK---------SGEPLASSTQYACDFNLFLEDS-ADN
RQNLSTQSLEHVEK----------ENSLCVSAANLSAESVH-----------SKA-----
LSKKDNEPEEVVVNF-KTRRKARR-ILSDDEDEDD--SLKGTSST---SPFSMSLLPLSS
VRQFDASTPKDN-SLRGQFFSPKISGSANKSMN-----SRRSLASRSSLINVILDDVEDI
EERLGNS---------GKAEGTEDDLEEQAEESSDEAAEQIE-DPSGERLPLENKCGRLT
MSKPSG-----CHLQTPLWEA---DPFC-AEPLVDSPQGK-------T-VQAANDYETLI
TRGKELKECGKIQEALNCLVKALDIKSSDPEVMLMTLSLYRQLRNA

----------------------MEAS---QGVAEAQALSPGQTAQ----YQRYVKEAKAA
TKNGDLEEAFKLFSLAKDIFPNEKVMSRIQNIQEALEELAEQ-------GD-EEFTDVCN
SGLLLYRELHDQLFEHQKEGVAFLYSLYRDGRKGG

PF00270 // ENSGT00590000083118_0_Domain_1 (156, 301)

ILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIIPTNLINTWVKEFVEWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWRQLSSFNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPAINRLLLTGTPIQNN

ENSGT00590000083118_0_Linker_1_2 (301, 536)

LQELWSLFDFACQGSLLGTLKTFKMEYENPITRARQKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEIQKKKSSNLEVRISEKNPDVGATCEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACQLLNLGTVKFSALDGNEGEDF
PDMDH--IDQITDETLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKTLRIDGTITHLLEREKRINLFQKNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYT
CDLSAKEEL---DVIEEPHYIQQRVQKAQFLVELESQNAGLLMEQQTTRNEGTWLREPVF
PSQTKKKCP-KFNNPQPQPSPLLTTHHI-------------QE-DISSQMANVIIDDPPE
EGEKDD-LSSIKTNITIPQD-------------GWHPCESTFDADSIATFPKGFE----S
LEETWNDSLLGLSKSFATEKEALPKEALQEGPTQEAPQEE-------PPGNFNYSLTKSI
KADLKPN-LDQLKDDEISHQHN-------PWPINPITNGNQNT----ESNVSVIEITD--
DLSASHSALQD----AQANE---ANL--------EEKLSTSSPQYACDFNLFLEDS-ADN
GKNPPSHSLEHMEK----------TNSLCDSAANSRSEFVP-----------RKTCLSWD
FTEKDDEAEEVIVNV-KIRSKARR-IVSDDEDEDDYDSFKGTSST---KSFHTSPFQFSS
VKQFDASTPKNNISPPGRFFSPIMSNSVNKSIN-----SRRSLASRRSLINMVLEHVEDM
EERLDDS---------SEAKSAKDYPEEEAEESSEEASEHTEEDPSGETLSSENKSSWLT
RAKPSA-----LVQETSLTES-E--PLS-S----DSPQDE-------A-VESVNDYETLI
MRGKELKECGKLQEALNCLVKALDIKSADPEVMLMTLSLYKQLSNS

----------------------MEAS---QGSAEVEALSPQLAAS----YLRYVQEAKEA
AKNGDLEEALKLFNLAKDIFPTKKVISRIQKLEEALEQLAAE-------DEDDEFTDVCN
SGLLLYRELYEKLFEHQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFAKWTPGMRVKTFHGSSKGERTRSLTRIQQRNGVIITTYQ
MLINNWQQLGSCNGQAFVWDYVILDEAHKIKSASTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 502)

TKKADNPEARLGEKNPGVEAICEMPSLTRKNDFIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELSVLKKLCDHPRLLSARACHLLNLETATFCAQDDNEQEGV
SDVDS--IDHLTDNALMQESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMLFLMALLERLHDEGQQTLVFSQSRQILNIIERLLKNK
HFKTLRIDGTITHLWEREKRIQLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFAVGDLQNSATQMQLQSLHAAQRRSDEKLDEHIAYLHSLGIAGISDHDLMFT
RDLSVKEEL---AVLEDSLYIQQRVQKAQFLVESESQNT---MGRQRPGNEEAWLKALAV
PSQQKKKGP-ELNKPQPRPSHMLT-NPT-------------QVEALSSQMANISIYDQSA
ESEPQD-H-STAHDVTLLQG-------------DPHHCESTFDAGTAATSPQEPG----D
TGGVWTDSSLGPAKCFAAENEAVQKKASQVSPGQESLPEN-------LLGSCNYSPRQSI
KADLGAN--LDLQHSVLSSHGS------------PTANENQNV----ESDVHTIEISD--
VLSASSSAPQG----AQASE---AQ------LELEENLLESPPQFACDFNLLLEDS-ADT
RQNLSSKLLEH-EK----------ENSLQSPAANSRAESAL--------------NLSLD
SSNKSDEEPEVIS-V-KTRSKARR-ILSDDE--DEEDALKGISST---SSLNTSPFQFFS
SVKQFASTPQNDTNPPGRFFSPKIPDNVNTSLN-----SRRSLASRRSLIHVVLDDVEDM
EERLGNS---------SEEESAPGHSEE---NNNDEASACTEQGPSGEAQASGNKPSSLS
VSEPGS-----QAPESSACAP---EPSSSSEPLVDPPQDP-------A-AEAADDYETLV
ARGKELKECGQIQEALDCLVKALDIKSADPEVMLMTLSLYKQLNST

------------MEASRRFPEAEA-----L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWIKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDIDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLRT--FSAQDGNEGEDS
PDVDH--IDQITDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVLMLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRIRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTHHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKANVTTLQD-------------GK----GTCSADSIAILPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADIGPN-LDQLKDDEILRHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEEPSASSPQYACDFNLFLEDS-ADN
RQNFSSQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDHPEEGAEESSGEASKYTEEDPSGETPSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQDK-------A-AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------MEASRRFPEAE--A---L--------SPEQAAY----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDGR

PF00176 // ENSGT00590000083118_0_Domain_1 (153, 373)

KGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDVDAICEMPSFSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKKLLMETHSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPK
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLSKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKEALQEGPKQEALQED-------PLESFDYVLSKST
EADLGPN-LDQPKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIKIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSGQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--NSFKDTSST---DPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------MEASRRFPEAEA-----L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHNQLFEHQKEGIAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQVTDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYT
CDLSVKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLLSTHHT-------------QEEDISSKMASVVIDDLPK
EGEKQD-LSSIKVNVTTLQD-------------GK----GTGSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADIGPN-LDQLKDDEILRHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEEPSASSPQYACDFNLFLEDS-ADN
RQNFSSQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSSI---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLM
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQDK-------A-AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------MEASRRFPEAEA-----L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 373)

HQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 536)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGT--FSAQDGNEGEDS
PDVDH--IDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRTRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLLSTHHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GK----GTCSADSIATLPKGFG----S
IEELRTNSLLGIEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADIGPN-LDQLKDDEILRHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEEPSASSPQYACDFNLFLEDS-ADN
RQNFSSQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWQ
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSINKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLM
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQDK-------A-AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

----------------------MEVS---RGFAEAGALSPEQAAS----YLRYVKEAKEA
TKNGDLEQALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFIDVCN
SGLLLYQELHN

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 297)

QLYEYQKEGIAFLYSLYRDGRRGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISTWLREFVKWTPGMRVKTFHGPSKDERTRNLCRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFLWDYVILDEAHKIKSSSTKSAICARAIPASNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 536)

IQNN
LQELWSLFDFACQGSLLGTLRTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSNPEVQLSEKSPDVGAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGAAKFSVQDEIEGEDS
SDVDH--IDQISDDTLMEESGKMLFLMDLLKKLRDEGHQTLVFSQSRRILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTITHLVEREKRISLFQQNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKNLDEHIAFLHSLRIAGISDHDLMYT
RDLSVKEEL---DVIEDSHYIQQRVQKAQFLVESESQNTELLMERQKMGNEGIWLREPVY
Q--TKKKRP-KVNKPQPQPSSHLPVYHT-------------QE-EISSLMASIIIDDLPK
EDE-KD-LSRIKLNDTIPQD-------------GRHPCVITLNDDFVTTLPKGCG----D
VEEIFPDSLSGM---------ALQKEASQEGFMQESEQES-------PLASFNYLPSKSA
RVDLGPN-LDQLEDDEVLHHCN-------PSPANPKTKEYQRP----ESNVSVIKIAD-D
DLTAAHSALQD----AQANE---AKL--------EEEPLASSGQYACDFNLFLEDS-ADN
GQNLSSQFLEHVEK----------ENSLCGSAANSRAESVH-----------SKACLSVD
LSEEDDEPEEV-VNV-KIRRKARR-IDSDNEDEH---TFKDTSST---NPFNTSPFPFLS
VKQFDASTPKNDISLPERFFSPKISDSINKSVN-----SRRSLASRRSLINVVLDHVEDM
EERLDNS---------SEAKVVEDHLEEGAEESGDEAPEHTKEDPSRETLSSENKSSQLS
TSKPGA-----LAQETSPGDP-E--PLS-DGQLVDSPQDE-------A-MEAVNDYDTLV
LHGKELKECGKIQEALDCLVKALDIKSSDPEVMLMTLSLYKQLNKT

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQ

ENSGT00590000083118_0_Linker_1_2 (372, 504)

KRKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVL
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVSTLQD-------------GRHPYEGTCSADSIATLSKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSGQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLI
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

----------------------MEAY---RGLAEAETLSSEQAAR----YLRYVKEAKEA
TKNGDLEEALKLFSFAKDIFPNEKLMSRIQKLQEALEELEEH-------ED-DEFTDVCN
SGLLLYRELYNQLFEHQKEGVAFLYSLY

PF00176 // ENSGT00590000083118_0_Domain_1 (149, 379)

KDKRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHALLIMPTNLISMWVKEFSKWTPGMRVKTFHGPSKDERTRSLNRVQQRNGVVITTYQ
MLINNWQQLSSCNGQVFVWDYVILDEAHKIKSSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIVRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQKTKSNIP

ENSGT00590000083118_0_Linker_1_2 (379, 503)

EVRPTEKNSGVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSTRVCHLLHLGTAKISGQDGNEE-DS
SDVDA--IAHVTDDTLMEESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLIDLLKRLRDEGHQTLVFSQSRQILNIIERLLRNK
HFKILRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKGSLIRQTTGDKKNPYRYF
NKQELRELFTVEDLQNSATQLQLQSLHAAQRRSDKTLDEHITYLHSLGIAGISDHDLIYT
RDLSVKEEL---DVIEESQYIQQRVQKAQFLVEFESQNT---VEKQRTGNEGAWPTAPLF
FSQTKKKCP-ELKKPQHWPSSLTTTHPT-------------QEGVISFQMANLSIED---
----QD-FSSVKMHMTMLQD-------------SMHSCENTFHTDSVATLTKEFG----S
VEEIWTASLQGTAKSFAVENEALQKKSLQEEPEQEALQEN-------PLGSFNYLASQSV
KADLAPN--LDLQDDKIFDHYS-------IWPSNPITNENQNT----KSNVSVIEISN--
ELSASHSVLQG----AQANE---AKS--------EGEPVASLPQYACDFNLFLEDS-ADN
TQNLSTQSLEYVEK----------ENSLCGSAANCSAESVH-----------S----NLD
SSKKDNDPEEVVVNV-KNRSKARR-IVSDDEDEDD--SFKGTSSI---SPFSTSLYHFSS
VKQFDASTPKDD-SLPGRFFSPKISDSINKSVN-----PRRSLASRRSLINVVLDHVEDM
EERLDNS----------KAEGTGDDLKEGAEESSDKASEHTE-DPSGERPSAENKSGGLT
VSKPLD-----SSLPTSPGSP---DPLS-AGLVVDSPQDK-------A-MEAANDYETLI
TQGKELKQCGKIQEALNCLVKALDIKSSDPEVMLMTLSLYKQLSNT

----------------------ME-S---YGLAEAEPLNSKQASL----YMRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPNKKLMSRIQKLQEALEELEKH-------EDDDEFTDVCN
SGLLLYRELYNQLFEHQKEGIAFLYSLY

PF00176 // ENSGT00590000083118_0_Domain_1 (149, 373)

RDERKGGILADDMGLGKTVQIIAFLSGMFDAS
LVHHVLLIMPTNLISMWMKEFSKWTPGIRVKTFHGPSKNERTRSLNRVQQKNGVIITTYQ
MLINNWQQLSSFNGQAFVWDYVILDEAHKIKSSSTKSAICVRAVPARNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIVRAREKDATPGERALGLKISENLMEIIKP
YFLRRTKEVVQK

ENSGT00590000083118_0_Linker_1_2 (373, 503)

KKSDISEVRYTEVNSGVDAICEMPSLSRKNELIIWIRLVPLQVEIYRK
FVSLDHIKELLKETCSPLAEIGVLKKLCDHPRLLSTRACHLLHLETAKTSAQDENKE-NS
LGIDD--ISHVTDDTLMEESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLIDLLKRLRDEGHQTLVFSQSRQILNIIERLLRNK
HFKILRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKGSLIRQTTGDKKNPFRYF
SKQELRELFMIEDLQKSATQLQLQSLHAAQRSSDKTLDEHIVYLHSLGIAGISDHDLIYT
CDLSVKEEL---DVIQESQYIQQRVQKAQFLVESESQNT---LEKQRMGSEGVWPPALLL
SSQIKKKCP-TLKKQQLWSSPLITIHPT-------------QEEAISFQMANVSIDD---
----QE-LSSIKTHMTVLQD-------------GMHSYENTFHTDSVATLPKEFG----S
IEELWTASLQETAKSFAVEHEDLQK-VLQQPPEQETLQEN-------PLRSFDYLASQSV
KAGLAPS--LDLQDDEILHHCN-------PWPSNPITNENENT----KSNVSVIEVSD--
ESSTSHSVLQG----PQANE---AKS--------EEEPLASSPQYACDFNLFLEDS-ADN
IQNLSTQSLEYVEK----------ENSSYGSAANSRTESVH-----------SKACLSLD
FSKEDSDTEEVIVRV-KNRNKARK-IVSDNEDEDA--SFKGTSSI---SPFNMSLFQFS-
EKQFDASTPKDD-SLPR--FSPKIPESVNQSIN-----PRRSLASRRSLINVVLDHVEDM
EERLDNS---------TKAEGTEDDVEEEAEESSDKASENTE-APSGEKLSSENKSFGPT
MSESLG-----FSLHTSSGDP---DPLS-VGPMVNSPQDK-------A-IEAENDYETLV
TRGKELKECGKIQEALNCLVKALDIKSSDPEVMLMTLSLYKQLNNT

----------------------MEAS---RGSAEAAALSPEQAAL----

PF00515 // ENSGT00590000083118_0_Domain_0 (50, 83)

YQRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPN

ENSGT00590000083118_0_Linker_0_1 (83, 136)

EKVMSRIQKIQEALEELAKH-------GD-DEFTDVCN
SGLLLYRELHNQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAT
LVSHVLLIMPTNLISTWIKEFVKWTPGMRVKAFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKTSSTKSAICARAVPARNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKASTPEVRLGEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACHLLNLGSVKFSVQGANEGEDA
SDVDH--IDQITDDTLMEESGKMIFLIELLKRLRDEGHQTLVFSQSRQILNIIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTVTHLVEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKTLDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNTELLVERQRAGNEGIWLREPLF
PSQTKKKCP-ELNKPQPWPSPLLPTYHT-------------QEEEISSQMASIVIDDMPE
ESENPD-VSNTKTDVTVSQD-------------GSHPPDSTSDADSVATLPEGCG----S
VEEIGTDLS-GM---------ALPKEPLREGPTQGTLQEN-------PLGDFNCLPSKAV
RADLGPN-PDQLNDDELLPHCN-------PWPISPVTNENQNT----ESNASVIEVAG-D
DLSASPGALQD----ARAHE---ARS--------EEEQLASSSQYACDFNLFLEDS-ADN
GQSLSRQSVQHVET----------EKSSCGSAANSQVELGC-----------DKARLSVD
LSETNDEPEEVVGNV-KGRRRARR-IVSDGEDEDD--TFKDTSGT---DALDTSPFRFLP
VRQFDASTPKSDISPPGRFFSLNIPDSINKSGN-----PRRSLASRRSLVNVVLDHVEDM
EERPESS---------REAEVATDYLEEGAEESSGEASECTE-EPEAN------KSSWLT
APEPGA-----SAPQAPPGDP-E--PLP-GRQLADSPQDE-------A-AEAAND

PF00515 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YDTLV
IRGKELKERGEIQEALNCLVKALDIKSADPEVMLMTLSLYKQLN--

----------------------MEAS---QGLAEVGTLSPQLAES----YLRYSQEAKEA
AKNGDLEEALKLFNLAKDIFPTKKVISRIQKLQEALEQLAEE--------EDDEFTDVCN
SGLLLYRELYEKLFEHQKEGIAFLYSLYKN

PF00176 // ENSGT00590000083118_0_Domain_1 (151, 373)

GRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFAKWTPGMRVKTFHGSSKNERIRNLTRIQQRNGVVITTYQ
MLLNNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAVCARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGFKMSENLMEIIKP
YFLRRTKEEVHM

ENSGT00590000083118_0_Linker_1_2 (373, 503)

KKADKPEVRPGEKNSGVEDICEMLSLTRKNDLIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGTVTFSAEDENEQEDA
SNMGS--IDHLSDNALMQESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLMALLERLQDEGHQTLVFSQSRQILNIIERLLKNK
HFKTLRIDGTVTHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELKELFTVGDLLNSATQMQLQCLHAAQRKSDEKLDEHIAYLHSLGIAGISDHDLMFT
CDLSVKEEL---DMLEDAQYIQHRVQKAQFLVESESQNT---KERP---SEENWLKAQEF
PSQQRKKG----NKPQPQPSRLLA-NPT-------------QVEAISSQMASISIYDQST
ESEPQE-L-SEAHDVTSLQG-------------DQHHFESTSDAGTIASLPQGAE----S
IGGVWTDSLLSPAKGFAADNEAVQKNELQASPGQEALSEN--------LGSFHYLPRQSS
KADLEPN--LDVQDSVVLYHQS------------PTANENQNL----ESNEPMIEISD--
DLSASPSALQG----AQAME---AQLELKK------DPLESPPQYECDFNLFLEDS-ADT
RQNLSSKFLEHVEK----------ENSLQRPAGNSGEESAH--------------NLSLD
SSNKIDEESEVIT-V-KTKNKARR-ILSDDE--DEEDAFKDT-ST---NSFSVSPLTFSS
VKHFDASTPQNDSNPSRRFFSPKIPDDVNTSLH-----PRRSLASRRSLINVVLDDMEDM
EERLDTS---------SEEESEPELSED---SN-EEAVACTEEQRSGATLASGNKHSSLT
ESEPTS-----PAPQSSPCAP---EPSS-SDPLLDPPQDP-------A-VEAANDYESLV
ARGKELKECGKTQEALNCLVKALDIKSADPEVMRMTLSLYKQLNT-

----------------------MEAS---RGFAEAGALSPEQAAR----

PF00515 // ENSGT00590000083118_0_Domain_0 (50, 83)

YLRYVKEAKAA
TKNGDLEEALKLFNLAKDIFPN

ENSGT00590000083118_0_Linker_0_1 (83, 130)

EKVMSRIQKLQEALEELAEH-------GD-DEFTDVCN
SGLLLYREL

PF04851 // ENSGT00590000083118_0_Domain_1 (130, 298)

HNQLFEYQKEGVAFLYSLYRDGRRGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISTWLKEFVKWTPGMRVKTFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRILLTGTPI

ENSGT00590000083118_0_Linker_1_2 (298, 536)

QNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSNPEVQLSEKSPDVGVICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGAVKFSVQDEIEGEDS
SDVDH--IDQISDDALMEESGKMIFLMDLLNRLRDEGHQTLVFCQS-RIINIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTVTHLVEREKRISLFQKNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQMQLQSLHAAQRRSDKKLDEHIDFLHSLRIAGISDHDLMYT
HDLSVKEEL---DVIEDSHYIQQRVQKAQFLVESESQNTEFLMERQKAGNEGIWLREPVF
LSQTKKKCH-ELNKSQPRPSPLLPTYHT-------------QEEEISHQMASVIIEDLPE
ESEKQD-LARRKMNVTIPQD-------------GRHPCASTFDADFVATLPKGCE----D
VEEIWTDSVSGM---------ALQKEASQEGPMREAQQES-------PQGSFNFLPSKSV
RADLGPN-LDQLEEDEILHHCN-------PWPANPEIKEYQRP----ESNVSVIKIAD-D
DLAAAHSALQD----AQVNE---AKL--------EEEPLASSAQYACDFNLFLEDS-ADN
GQNFSSQSLEHVEK----------ENSLCGSAANSRAESVH-----------SKACLSVD
LSEKDDEPEEVVVNV-KVRRKARC-IDSDDEVEHD-TFITDTSGT---NPFNTSPFPFLS
VKQFDASTPKNDISPPGRFFSPKISDSLNKSIN-----SRRSLASRRSLINVVLDHVEDM
EERLDNS---------SEAKVAEDYLEEGAEESSGEAPEHTEEDPSRETLSSENKSSWLS
TPKPGA-----LAQETFPGDP-E--PLS-GGQLVDSPQDE-------A-LEAADD

PF00515 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YETLV
LRGKELKECGKIQEALDCLVKALDIKSSDSEVMLMTLSLYKQLNKT

----------------------MEVS---HGLAEMETLNPHQAAS----YLRYVKEGKEA
TRNGELEEALKLFNLAKDIFPTKKVLSRIQKLQEALEQLAEE--------EDDEFTDVCN
SGLLLYRELYEQLFEHQKEGIAFLYSLYKG

PF00176 // ENSGT00590000083118_0_Domain_1 (151, 373)

RRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFAKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSDNPEARLNEKNPGADPICEMPSLTRKNDLIIWVRLVSLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLETVRFSAQEGNEEEDS
SDVNS--IAHITDDALMQESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMALLKRLRDEGHQTLVFSQSRQILNIIERLLKNK
HFKTLRIDGTITHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTVEDLQNSVTQLQLQSLHAAQRRSDEELDKHIAYVQSLGIAGISDHDLMYT
HDLSVKEEL---DVIEESQYIQQRVQKAQFLVEFESQNT---MGRQRTGNEE--FRASVF
PSQTKKKGH-ELNKPQSQPSPLLTPSPA-------------QEEDISSHMASVSIYDQSR
ESEPQR-ECSEVKNLSVLQD-------------DRHQPESTFDAGSTATLPQGPG----S
IGGIGTDSVLGIAETFATENEAVQTKALQELPKQETLQET-------LLGSFNYLASQSG
KVDLGPN--LDLQDEESLYYCG-------PQPVNPTVNENQNT----KSDVPIIEVSD--
DFPASPGALQG----AQASE---AKM--------ENDLLALSPQYACDFNLFLEDT-ANA
TQNLSDQSLEHVEK----------KNSLHGSAADSRAESAL--------------NLSVD
SSENDELEEELVI-V-KARSKARR-IISDDE--DENDALKGTSST---SSFSTSPFQFSS
VKQFDASTPKNDTIPHGRFFSPKIPDNVNKSVN-----SRRSLASRRSLINVVLDDIEDM
EEKLDNS---------SDSESAQGRSEE---ESSDEALGCTE-DPSGEPLSSENKPSSLT
MPEPSS-----LAPQSSPDAP---EPLSR-EPSVDCPQDT-------AVEEATNDYDTLV
ARGKELKESGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNN

------------------------MC---FHPCERSQIGKHIDTK----SEKYIKEAKEA
TKNGDLEEALKLFNLAKDICPTQKVMSRIQKLQEALEQLAEE---------GDDFTDVCN
SGLLLYRELHKQLFEHQKEGIAFLYGLYKDGR

PF00176 // ENSGT00590000083118_0_Domain_1 (153, 373)

KGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLISTWIKEFSKWTPGMRVKTFHGPSKDERTRNLRRIQDRNGVIITTYQ
MLINNWQQLSSFKDQKFVWDYVILDEAHKIKSSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGFKISENLMEIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KQSDNPEVGPSEKSPGVVVSCEMPSLTRKNDFIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACQLLNLGTVKFSAQDESEEEDS
STMNS--IDHISDDRLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMALLKRLKYEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVIIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQCLHAAQRRSDEELDDHIAYLHSVGIAGISDHDLMYT
HDLSVKEEL---NVIEESQYIQQRVQKAQFLVEFESHNK---MERPETGNEEAWLRASVL
PSQV-KKCP-EVKKPEHQPLPLITSHLT-------------QEEDISFQMANVSIDNQSR
VSESQD-LPRVEMSGAVPED-------------VRHQHENIFDADS-VTGPKGVE----S
VGGIWTDSSLGTANMFATENETMQKKALQEAPKQADVQEN-------LLGSFSYLPSP-G
KAHLGPN--LDLQDDESLYHYD-----------------AENI----ESNVSVTEIAD--
NLSASHSALQG----AQANE---AKL--------QEGVSASSVQYACDFNLFLEDS-ADS
RYNLCGQSLEHVEN----------ENILSGSAANLRAESVH--------------NLSLD
SSKN-DEPEEVVS-I-KNRNKARR-IVSDDE--DEDDSCKGMSGP---SSFSISPFLFSS
LKQFDASTPKDDTSPSGRFFSPKLADIVSKSVN-----SRRSLASRRSLINVVLDHIEDL
EEKLDDS---------SEAESTQDHSEEE--ESSDEAAEHTQEEPSGEIPTSESKPRSPT
MSEPSL-----QALQASPDAP---EVLS-SEPLVDSPQDK-------A-AEAATDYETLV
ARGKELKERGKIQEALSCLVKALDIKSADPEVMLMTLDLYKQLSNT

---------------------------------------------------RYVKEAKEA
TKNGNLEEALKLFKLAKEVFPNDKVLSRIQRLEEALAEIAKE--------GDDEFIDVCN
SGLMLYRELHD

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 296)

QLFEYQKEGVAFLYSLYKENRKGGILADDMGLGKTIQIIAFLSAMFDAE
LVKYVLLIMPTSLISTWIKEFGKWTPGMRVATFHGSSKSERTRNLNRIQRKNGVAVTTYQ
MVINNWQQLSQLDGNEFVWDYLILDEAHKIKSSSTKSSIAARAIPVKNRLLLTGT

ENSGT00590000083118_0_Linker_1_2 (296, 491)

PVQNN
LYELWSLFDFACQGSLLGTSKTFKMEYENPITRAREKDATSGEKALGLKISENLMTLIKP
YFLRRTKDDVQKKNNTKAQSSLPEKKLGDDVVCEIPSLSRKNELIIWVYLVPLQEEIYRK
FVSLNHIKQLLMETRSPLAELTILKKLCDHPRLLSARACSLLGLKEGIFFNKGKNQEG--
--QSEIQIDQ

PF11496 // ENSGT00590000083118_0_Domain_2 (491, 648)

VPPESLMKESGKVIFLMALLKRLQDEGHQTLVFSQSRRLLDIIEHLLKKE
NFKTLRIDGTVTQLPERQRRIDLFQQSQDASVFLLTSQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDQKNPVRYF
SKQELRELFTIGDFRSSPTQVQLHSLHAGHRKTDKTLEDHIAYLHTLGIAGISDHDLMFT
HDVSVQEES----EAGESQYIQERVQKAQLLVELESQNNKLLLNNGRNRVEEGWPKQFGS
-SKAKKNSS-DSKAAC-LHSPPELVDLT-------------QNDSFSSGMANLSIVQSNE
TTRD---LSAMNLDVSAKES-------------DIDIAENKADHELITV------FSSEE
CLEMETSKVNNSDDSV-----QILSDSNRESKKQLADETK--------------------
AVDIKPNPD-RTAKSEILLPFS--------------------PEKSMEFDTPLICIAD--
SDS---SA-----------VENLP----SNEDKLEEEPLDSSPQYAGDFNLFLEDS-AES
EQNHSKKFLAPSER----ES-------------NIMEFTPIPRGLGS-FKYPQLESL---
-SDQESELEDNILPV-KTRYKTRR-IVSDDDDDDDDAMTE----------GMLPPL-PNS
L-VQFSSTPKASTSQSELLLPEIGSGENTP-AS-----SRRSLASRRSLINVILDHVEDM
EEEASE------------QKNTDKYLEVEM-GEYNQEIEYSEEESAGE------------
------------------------------------------------------------
----------------------------------------------

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------LEEDISSKMASVVIDDLPQ
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAIQKETLQEGPKQEALQED-------PLESFNYVLSKSA
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-PDN
RQNFSGQSLEHVEK----------EKSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDVD--DSFKDTSST---NSFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

----------------------MEAS---RGFTESQALKPEQAAQ----

PF00515 // ENSGT00590000083118_0_Domain_0 (50, 83)

YLRYVKEAKEA
TKNGDLEEALQLFNLAKDIFPN

ENSGT00590000083118_0_Linker_0_1 (83, 136)

EKVMSRIQKIQEALEELAEN--------GDDEFTDVCS
SGLLLYRELHNQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQKEGVAFLYSLYKDGKKGGILADDMGLGKTVQIIAFLSGMFDAS
FVNHVLLIVPTNLISTWIKEFAKWTPGMRVKTFHGSNKDERARNLSRVQQRNGVIITTYQ
MVINNWQQLSSLNGQKFVWDYVILDEAHKVKTSSTKSAMCARAVPASNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKIEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKEKPSNQEAIFSEKNPDVSVSCEMPSLSRKNDLIVWIRLVPLQKELYRK
FVCLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARASSLLNIGAVKFSVQDENEE-DS
SDGGH--INHITDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTVTHLIEREKRIDLFQKNKDYSVFLLTTQVGGVGLTLTAATRVVIYDPSWN
PATDAQAVDRVYRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQATGNKKNPFRYF
SKQELRELFVIGDFQNSATQLQLQSLHAAQRRSDKKXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEPVF
LSNK----P-SHNNPKPWPLLV-GTYDF-------------QEEEISLKASVVIDDDLPR
ESENHD-LSSEKMNESVLQD-------------GTQD-----GTDSVATLPKGCR----S
IEKVCVTSFLGVTESFTTESEALQNKSLRERSVQEALEEN-------PLGRFNSLLSKSV
RSEPNPG---LIKNDEILHHCG-------SWSINPVTKENQNT----ELNAFVIEISD-D
DSSASHSELQD----TQANK---AKL--------EEEPLA-SSQYVCDFNLLLEDS-ADN
RQKFSSQSLEHVKQ----------ENSLCDSTSNSRANFVH-----------SNTYLSLD
LSEKEDNESEALVNL-KVRRKARR-IASDDED----DTCKSSPSM---NTFSASPFQYSS
VKQFDASTPQNNISSPGRFFSHKLPDSFNRSLN-----SRRSLASRRSLANVVLDHVEDM
EERLDNC---------EAEVVEDYLEDEGAEESSGEASECMAKNPSGEMLSTENRPSWLT
IPEPAA-----VAQKISPDDP---KPLF-GEQVVDSPQEK-------A-AETVND

PF00515 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YELLV
TRGKELKECGNVQEALNCLVKALDIKSSDPEVMLMTLNLYKQLNKT

------------------------------------------------------------
------------------IRPSEKLRGRMQRLEEALAQL------------EGRFVDVCG
SGLMLYGELHAKLFQ

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQREGVAFLYSLHRDGRPGGILADDMGLGKTIQIIAFLSGMFDGE
LIQHVLLIMPTTLVSSWLAEFARWTPGLRVKEFHGSSKAERTRNLERVRRRNGIVVTSYQ
MLINNWKQLASCQEQDFVWDYIILDEAHKIKCPSNKTTKCVYAIPARHRVLLTGTPVQNN
LQEMWSLFDFACQGSLLGTAKTFRMEYENPITRAREKDATLGEKALGLKISENLMTIIKP
YFLRRTKEDIKKSHADKPDAPLPED-PSEARAPVMPSLTRKNDFVVWVYLSPTQEKIYRN
FLCLDHVKEVLMTTRSPLAELTVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACIQLGLDGQECSEEDPSSEA-G
VLSGANKIDHLSVETLIQESGKMLFLVGLLERLREEGHRTLVFSQSRKMLDIIEQ

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

VLSRR
QFKIMRIDGTVTHLTEREKRISAFQSNKDYSVFLLTTQVGGVGITLTAANRVVIFDPSWN
PATDAQAVDRAYRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTLEDTRTSTTQIQLQSLHATQRKTDLQLDEHIAYLHSLEMFGISDHDLIFT
REMTHE---EQAESEEAHQYIQKRVQKAHELVQLESQLRDMRMEGIRNAVEETWSRPPEL
ASQAKKRSP-GLNNINNMVSPPVADKK----------DVEVQILDVSSKMTSLTVDELGE
EKLAQV-MPSMDTELLS-------SSKIEEQ-PDTQGSGQNMDSSIISLSPGLRPLDKES
PS----LKQ--------------------------------------KQRSPVPHFADES
GVADHPRKLKD---AEMSVQVL--DLLA----VSE-TEGNDIPEPALAAT--PPNLPN--
VTPEAHAG-----------FQKSRVVEA-----SLEEMSVPSLQDQVDFNLVLEES-EDG
WQDV-SNGERSLEH-PADEGFQLKMGSLCKSPAKTV-------------AAEEDPNNSLQ
GGEASEENSVILVSG-RRKKSVKR-IVSDSEDEDSSVMISEEEQSDKKSSPLNVPL-HQF
LEGITASTPKSNRSLSKNIFSPKLT------NS-----GSRSTASRRSLINKVVDEVEDI
GEIM---GTTDEEENS--DEEQEDLVEDEA-EECSAESVEPEEEPAGETLNSTEESFHVE
GMQS-EADETESSQEESTGDA----ELQSGEQIEYCTQGRASE-------EEDAS

PF07719 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YSTLV
DRGKKLRDDGNLQEALSCFQQALDIKSEDPEVMLMTLNLYKQLAQ-

------------MEASGRFPEAEAL-------------SPEQAAH----YLRYVKEAKEA
AKNGDLEAALKFFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 378)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWLKEFVKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFLWDYVILDEAHKIKTSSTKSAICARAVPASNRLLLTGTPIQNN
LRELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATAGEKALGFKISENLMAIIKP
YFLRRTKEEVQKK-TSN

ENSGT00590000083118_0_Linker_1_2 (378, 506)

PDVKLNENNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETQSPLAELGVLKKLCDHPRLLSTRACGLLNLRTVTFSARDENEGEDS
PDMGH--IDQISDDTLMEESGKMIF

PF00271 // ENSGT00590000083118_0_Domain_2 (506, 615)

LMGLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEKSHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLRERVF
PSSTKKKCP-KLNKPQPQPSPLISTHHT-------------QEEDISSKMASVVIDDLTE
ESEKQD-LSSIKMNATTLQD-------------GRHPCESTCSAYSIATLSKGFG----S
VE-VFMNSSLGMEKSFATKNEALQKETLQEGPKQEALQED-------PLATFNYLPSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DFSASHSVLQD----AQANE---AKL--------KEEASASSPQYACDFNLFLEDS-ADN
RQNLSSQSLEHVEK----------GNRLCGSAANSRAGFVH-----------SKTCLSWE
FSKKDDEPEEVVVKA-KIRSKAGR-IVSDDEDED--DSFKDTSNT---NPFNTSLFQFSC
VKKFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLSSRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASQCTEEDPSGETQSSENKSSWSM
MSKSSA-----LAQETSLGSP-E--PLS-GEQLVGSPQDK-------V-AEAANDYETLV
KRGKELKECGKLQEALNCLVKALDIKSADPEVMLLTLSLYKQLNT-

----------------------MEAS---QGSVEVETLSPQLAES----YRRYVQEAKEA
AKNGDLEESLKLFNLAKDIFPTKKVMSRIQKLQEALKQLAEE----E--EDDDEFIDVCN
SGLLLYRELYEKLFEYQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFAKWTPGMRVKTFHGSSKSERTRNLTRIQQRNGVVITTYQ
MLLNNWQQLASFNGQVFVWDYAILDEAHKIKSASTKSAVCARAVPAKNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 505)

TKKADNPEARLGEQNPAVKAVCEMLSLTRKNDLIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACRLLSLGTATFSAQDENEQEDV
SNMDS--IDHLTDNTLMQESGKMI

PF00271 // ENSGT00590000083118_0_Domain_2 (505, 615)

FLMSLLERLQDEGHQTLVFSQSRQILNIIERLLKNK
HFKTLRIDGTVTQLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
TKQELKELFTVGDLQNSATQMQLQCLHAAQRRSDEKLDEHIAYLHSLGIAGISDHDLMFT
CDLSVKEEL---DMLEDSQYIHQRVQKAQFLVESESQDT---VERQRTGIEKTWLKVQEF
PSQHKKKGT-EFNKRQPQPSRLLT-NPT-------------QVEAVTSQMASITICDQSA
ESEPQE-H-SEVHD-VTSLK-------------GGHHFDSTSDAGTIASLPQGAE----S
IGEVSTDSLLSPAKGFTAENDAMQKKGLQASPEQEAPSEN--------LGSFHYLPRESS
KADLGPN--LDLQDSVFLYHCS------------PTANENQNL----ESDVPMIEISD--
DLSAPRSVLQG----AQAIE---AQLELKED-----DPLESPAQYACDFNLFLEDS-ADT
RQNLSSKFLEHVEK----------ENSLQSPAANSRAKSAL--------------TLSLD
SSK--SDESEVIS-V-KTKNKARR-IFSDDEDEDEQDAFKGS-ST---NSINISPFPFSY
MKQFDASTPQSDSSPSRKFFSSKIPDEVNTSLH-----SRRSLASRRSLINVVLDDVEDM
EERLDNS---------SEEESEPGLSEE---SNEEEALACTEEQPSGATLASGSKSSNLT
MSEPTS-----PAPQSSPCAP---EPSS-SDPMLDPPQDP-------A-VEAGNDYESLV
ARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNI-

------------LKRVRRGPRTESSG---R--------KNTEEML----FYRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEH

PF00270 // ENSGT00590000083118_0_Domain_1 (137, 299)

QKEGIAFLYRLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQ

ENSGT00590000083118_0_Linker_1_2 (299, 536)

NN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQKKKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPISSITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSGQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQV----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

-------------------------QLTPLRFRPLISLERHST----LLSCRYLKEAKDA
TKMGSLEEALRLFNLAGEIFPSDKVKHRIKRIEETLEELAEE--------KDNEFTDVCN
SGLMLYRELHHQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 375)

HQREGVAFLYSLFRDGKKGGILADDMGLGKTIQIIAFLSGMFDAE
LVNYVLLVMPTTLISTWTREFAKWTPGIRVKNFHGASKTERTKNLERIQRKTGVIITTYQ
MLINNWQQLSSLNGREFVWDYLIFDEAHKIKTSASKTAICARSIPAHNRILLTGTPVQNN
LQELWSLFDVACQGSLLGTSTTFKMEYENPITRAREKDATPGEKALGFKISENLMTIIKP
HFLRRTKEDVQKRT

ENSGT00590000083118_0_Linker_1_2 (375, 479)

ASQPKSNLSEKSQDDDLAPEMPSLSRKNDFIIWVRLTSLQEDIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACTLLGLEGGGFSDQDEN-GT

PF11496 // ENSGT00590000083118_0_Domain_2 (479, 647)

-D
HYSDINRIGQLPDQTLMEESGKLMFLMALLKRLQREGHQTLVFSQSRKMLDIIERLLTNT
HFKILRVDGTIAQLGEREKRISLFQKNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLVRQTTGDKKNPFRYF
SKQELRELFVIEDFRLSKTQQQLQSLHSAQRKTDEELDGHIAYLHTLKIAGISDHDLMYT
RDAAAH---EEAQEMEERRYIQQRVQKAQQLVELESQHNELLLERIRTGTEGSWLRPPIF
SSQPKRKPP-ESKTGQPRSLSPVRRPIL------SSETVDLAQDDVSSKMTGLVLDDSDE
EGETAE-RSSGKTPKFG-------AGPSPALPTKKCPRETNRSKDSLMETSTIRIPDSDS
---------------------EVLRDSVMECSRHPSTSAV-V-----------------D
LTESQP-PL---PEAEMSVQAL--DSLASPAGKEAGVRAGASPSIDRP--------AG--
TQSASPSV-----------FRSSGLSEI----KVRGESLVSSLHYTNDFNLVLEDS-VEG
AQKP-SVASL--EG-IQNEDL--LDGSV---------NNSKPDGHHSV--------RSVH
LSDTEGEGESELVVV-MGKKKARRIIVSDSEDGE-------------EPEALMSPL-RNS
GQEFRASTPKWETSKSDPVFSPGAL------GS-----GKKPITPPA-RPDVDLDRVADV
EGLEISRRAERIEDGSESDGPESEFWEEEA-EEGSVEEDDYSEEPAGETLGTESESCNFS
MSESDAGREGPSAGESST-------KMQVED----------DISNHLNSVSETDKYDALV
KRGKELKGRGNLQEALDCLLQALDLKS-DPEIMLLTLGLYKQLNVN

------------MEASRRFPEAEA-----L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHNQLFEHQKEGIAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEDRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQVTDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYT
CDLSVKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLLSTHHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GK----GTGSADCIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADIGPN-LDQLKDDEILRHCK-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEEPSASSPQYACDFNLFLEDS-ADN
RQNFSSQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSSI---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLM
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQDK-------A-AEATSDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

----------------------MEAS---RGFAEAGVLSPEQAAR----YLRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GE-DEFTDVCN
SGLLLYRELHNQLFEYQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RRGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISTWLREFVKWTPGMRVKTFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSLNGREFVWDYVILDEAHKIKTSSTKSAICARAIPARNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 502)

KKSSNPEVRLSEEDPDADAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACQLLNLGAVRFSVQDEIEGEDS
SGVDH--IDQVSDETLMEESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMTFLMDLLKRLRDEGHQTLVFSQSRQILNILERLLKNR
HFKILRIDGTITHLVEREKRISLFQQNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHASQRRSDKNLDEHIAYLHSLRIAGISDHDLMYT
RDLSVKEEL---DVIEDSHYIQQRVQKAQFLVESESQNTELLMERQRTASEGIWLREPVF
PSQTKKKCA-GFNKPQPRPSPLLPTHHI-------------QEEDISSQMASIIIDDLPE
ESEKQD-LFRIKMNDTSPQN-------------GRHPRDSILDANFVDTLPSGGG----K
VEEIWTDSLSGM---------ALQKEALQEGPIQEVLRES-------PLGSFSYLPNKSV
RADIEPN-LDHLEDDEILHPCN-------PWPVNPITKESQNP----ELSVSVIQIVD-D
GLTAAHSTLQD----AQVNE---VKL--------EEEPLASSAQYTCDFNLFLEDS-ADN
GPNLSSQSVEHGEK----------ENSLCGSAANSGVEFVH-----------SKACLSVD
LSEKDEEPEEVVVNV-KVRSKARR-IDSDDEDAND--TFKDTSST---NPFNTSPFPFLS
VKQFDASTPKNDISPPGSFFSPKISDSINKSIN-----SRRSLASRRSLINVVLDHVEDM
EERLDNS---------SEAKVAEDFLEEGAEESINEAPECTEE-SSGETLSSENKSSGLS
TPGPGG-----LAPETSSGDP-E--PSS-GGQLVDSPQDE-------A-VESVNDYETLV
LRGKELKACGKIQEALDCLVKALDIKSSDPEVMLMTLSLYKQLNKT

----------------------MERS---QSLPALQALNPL-ATS----ILRYVKEAKEA
TKNGDLDEALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFTDVCN
CGLLLYRELHN

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 297)

QLFEHQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAA
LVNHVLLIMPTSLISTWVKEFAKWTPGMRVKAFHGPSKDERIRNLSQIQQRNGVIITTYQ
MLINNWQQLSSLNGQVFVWDYVILDEAHKIKTSSTKSAICARAIPANNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 536)

IQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKPDNPVTRHSEDNPDAGAICEMPSLSRKNDFIIWIRLAPLQEKIYRK
FVSLDHIKVLLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGVLGFSSQDENDGKNS
SDVDR--IDQATDDTLMEESGKMIFLLDLLKRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKTLRIDGTITHLLEREKRIHLFQQNKDYSIFLLTTQVGGVGLTLTAATRVIIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYT
HDLSGNEEL---DVIEESNYIQQRVQKAQFLVEFESQNTELLIERQRSGSEEARLREPIF
PSQIKKKCP-ILNKPQPRPSPLITTHYT-------------QQEDISSQMASLNIDYLAE
ESETQG-LSNIQVNLTVLQD-------------GRHTHESKFDAQFAAPLPKECG----S
VEEIWTDSLLEMTKNCATENEVIQKEALGAGLKQEILQEV-------PLGVVNYLPSKSI
RVDLEPN-QSQPEDDESLQHCN-------LWPINPVTSQNENT----ESNTSIIEITN--
DLSASHSGLQD----AQANG---AKL--------EEKSLALSPQYACDFNLFLEDS-ADN
GQNLSIQPLVHADR----------ENSVCSSVTNSREGLVH-----------SKACLNLD
FSEKDNEPEEEIVNV-KIRSKARR-IVSDGEDEGD--SFKDISST---NPFNTSHFHFSS
VKQFDASTPKNDISLPGRFFSPKVSDSGNKSIN-----SRRSLASRRSLINVVLDHVEDM
EERLDNS---------SEAESAGDYLEEGAEESSGEASEYTEEDPSGETLSSENRSSWLT
TSKPDS-----LAQETSIGDP-E--PLP-GKQLVNSPQDK-------A-VEAVNEYETLV
MRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNKT

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSDQSLEHVEK----------EKSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

----------------------METY---RGLSEAETLNTEQAAR----YMRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPNEKLMSRIQKLQEALEELEEH-------EDDDEFIDVCN
SGLLLYRELYNQLFEHQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 379)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLISMWVKEFAKWTPGMRVKTFHGPSKDERTRSLNRVQQRNGVVITTYQ
MLINNWQQLASCSGQAFVWDYVILDEAHKIKSSSTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACHGSLLGTLKTFKTEYENPIVRAREKDATPGEKALGLKMSENLMEIIKP
YFLRRTKEVVQKRKSNIP

ENSGT00590000083118_0_Linker_1_2 (379, 504)

EVRPTEENSGGDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLLETRSPLAELGVLKKLCDHPRLLSTRACHLLHLKTAKISAQDGNED-DS
SDMDD--ISHVTDDTLTEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMALLKRLRDEGHQTLVFSQSRQILNIIEQLLRNK
HFKILRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKGSLIRQTTGDKKNPFRYF
NKQELRELFTIEDLQNSATQLQLQSLHAAQRRSDKTLDEHITYLHSLGIAGISDHDLIYT
HDLSIKEEL---DVIEESQYIQQRVQKAQFLVEFESQNT---VEKQRTGNEGAWPLAPLF
SSQTKKKCP-ELKKPQRWPSSLITTHPT-------------QEEALSFQMANVNIDD---
----QD-LSSVHTHTTMLQD-------------GTRSCENAFHTDSVATLPREFG----S
MEEIWTASLQETAKSFATENKALQE-SLQEESEQEAQQEN-------PLGSFDYLASQSV
RDDRAPS--LDLQDDEDLYHCD-------PWPTNPITNESQAI----KLNVSVIEVSD--
ESPASHSVLQD----AQTNE---AKS--------AGEPLASSLQYACDFNLCLEDS-EGN
TQNLSTQSLECVEK----------ENNLCGSAASSRAESVH-----------SKACLSLD
SSKKDKDPEEVVVGV-KSRSKARR-IVSDDEDEDD--SIKDTSST---SPFHTSLFQFSS
EKQFDASTPKDD-ILPGRFFSPKIPDSVNKSIN-----PRRSLASRRSLINVVLDHVEDM
EERLDSS---------SKAEGTEDDLEEGAEDSSDRASENTG-DPSGERLSSENKSVGLT
TSKPPS-----FNLQTSPGAP---DPLS-AGPMLDSPQDK-------S-VEAADDYETLI
TRGRELKECGKIQEALNCLVKALDIKSSDPEVMLMTLSLYKQLSNT

-----------------------AATATGNAVEK--LLSPGRA----ANYQKYIKEAKEA
TKNGNLEEALKLFYSAKDVFPNDKVLRQIQKLQEALEELSIE--------GEDEFVDVCN
SGLMLYRDLHDR

PF04851 // ENSGT00590000083118_0_Domain_1 (133, 297)

LFEHQKEGVAFLYSLYKERRKGGILADDMGLGKTVQILAFLSAMFDAE
LVRFVLLIMPTSLISTWTKEFDKWTPGMRVATFHGSSKNERIRNLNRIQRNNGVAITTYQ
MLVNNWQQLSQLDGKEFVWDYLILDEAHKIKSSSTKSSIAARAIPVKNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 536)

IQNN
LYELWSLFDFACQGSLLGTSKTFKIEYENPITRAREKDATPGEKVLGLKISENLMALIKP
YFLRRTKEDIQKKSTNKPLRNLPEKNLDDDIIYEIPFLSRKNELIIWVYLVPLQEEIYRK
FLSLNHIKQLLMETHSPLAELTVLKKLCDHPRLLSARACSLLGLKEGNFSGEDESQMA--
--HSNIQIDQVPHESLMQESGKVIFLMALLKRLQDEGHQTLVFSQSRKLLDIIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKKE
NFKTLRIDGTVTHLSERQRRIDLFQQSQDVSVFLLTSQVGGLGLTLTSATRVIIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLISCGTVEEKIYRRQVFKDSLIRQTTGDQKNPARYF
SKQELRELFTIGDFRSSATQLQLHSLHAGHRKTDKKLEEHIAYLHTLGIAGISDHDLMFT
HDVSAHEES----EVGESQYIQERVQKAQLLVALESQNNELLLNNNRTRVEETWVKEPAS
-SKPKKKCS-GFNVVH-HLSPPIIVDLT-------------QKDLIDSEMANLSIENS--
EVHG---LSAMNVDVSVKQC-------------DVHISEHKIDDEFITT------FSNEQ
CHEMEISKTNNPDDSI-----QVLLDNTQESIKQLTNGTA--------------------
KVDFESNSD-QLTNCEILLFIN--------------------PEKSVELSTSLISLAG--
PDP---TA-----------LENSS----PNQDKFEKESVASSLQNAGDFNLFLEDS-LEN
VQNHSKQSLESIER----EN-------------SIWDSAANPKGQSI-FGYPQFENL---
-SDQESDLEEEIVPV-KTRYKTRR-IVSDDED---DFVTE----------RILLPF-PDS
LLTQFNSTPQSNRSQNELFSSEICSSGNNS-AI-----SRRSLASRRSLINVILDNVENM
EEDANE------------YKGTDKYLEEEESAEYSQESEHSEE-PVGEILLSQSELGSLC
VSHSDLVQSA--SGEDSQE---------------------TTAHNPSSA-PMTDEYEALV
KCGKELKKSEKIQEALNCLLKALDLKSTDPEVMLLTLNLYKQLNQT

----------------------MEAS---RGSAEAAALSPEQAAR----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFTDVCN
SGLLLYQELHNQLFEHQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 419)

RKGGILADDMGLGKTVQIIAFLSGMFDAT
LVNHVLLIMPTNLISTWIKEFVKWTPGMRVKTFHGPSKNERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKSSSTKSAICARAIPTRNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATQGEKALGFKISENLMTIIKP
YFLRRTKEEVQKKKSSNPEVRLREKNLDVDAICEMPSLSRKNDFIIWIRLAPLQEEIY

ENSGT00590000083118_0_Linker_1_2 (419, 502)

RK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACLLLNLGSVKFSVPGENEGEDS
SDVDQ--IDQITDDTLMAESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMLFLIELLERLRDEGHQTLVFSQSRQILNIIECLLKNR
HFKILRIDGTITHLVEREKRINLFQQNKDYSVFLLTTQIGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGD-KNPFRYF
TKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNTELLVERQRTGNEGIWQREPVF
PSQTKKKFP-ESRKLQPWPSPLL----T-------------QEEEISSQMASIIIDDLPE
EHGNQD-LSNVKMNVTVLQD-------------GSHPCESTFDADSVATLPKWCG----S
VDEICTDPM-GM---------AIQKETLQEGPTQEAPQED-------PLGNFNYSLSKLV
TADLEPH-LDQLKDNEILLNCS-------PWPMSLMISANQNT----ESSTSVIQIAD-D
DVSASHGALQD----AQGSE---AKL--------EEEPSASSSQYACDFNLFLEDSAADN
GQDLSRQSLQHVEN----------ENSLCGAAANSGAEVEH-----------GKAHLSMD
LSETNDEPEEVIVNV-KVRRKARR-IVSDGEDEDD--TFKDTSST---DPFNTPPFQLLS
VKQFDASTPKSDISPPGTFFSLKMADSINKSVT-----SRRSLASRRSLVNVVLDHVEDM
EERLDNS---------SEAEVAEDYLEEGAEESSGEVSECTE-DPPGKTLPSENKL---M
TPEPHA-----LAQETSPGNP-GQTSLS-GRQLVDSPQDE-------A-MEAVNDYETLV
IRGKELKECGKIQEALNCFVKALDIKSADPEVMLMTLSLYKQLNKP

--------------------------MAAVIIAKT-KSPGRVK----QRQRAVVQMEQKT
P--KTRKRS----SKVHKIQPKEHPTEDVQDAEEKLMSLALDK-----DGDGDEFVDVCQ
SGLMICRELHD

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 296)

KLFEHQKEGVAFLYNLYHKKRQGGILADDMGLGKTIQIIAFLSGMFDAG
LVRSVLLIMPVTLVNNWMREFANWVPGIRVKVFHGTSKKEREQNLEQIQRRTGVLLTSYQ
MVLANWEQLSNLDGQPFVWNYVILDEAHKIKSPSAKTTKSVYGIPAVNRILLTGT

ENSGT00590000083118_0_Linker_1_2 (296, 537)

PVQNN
LRELWALFDFACQGSLLGTAKTFKMEYESPIMKAREKDATLGEKALGLKISQNLMAIIKP
YFLRRSKGEILKLNSERS-VCLTGE-ERDYIALEMPSLPRKNDFIVWVYLAPMQEDIYRN
FLSLDHIKELLMTTRSPLAELTVLKKLCDHPRLLSAQACASLGLEVSEYSEPTDQ----S
TLSMTQDIKRVSDKLLIEESGKLVFLVALLEKLQEEGHQTLVFSQSRKMLDIIEHI

PF00271 // ENSGT00590000083118_0_Domain_2 (537, 615)

LTKR
SFRLMRVDGTVTCLAEREKRVRQFQMDKSYSVFLLTTQVGGVGLTLTSATRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIQQSTGDKKNPYRYF
TQQELRELFTLEDTTSSATQLQLQSLHATQRNSDLELDEHIAYLHTLEMFGISDHDLMYT
CETGQEEEEEEAEDDEAHQYIEHRVKKAQELVQLESQLNDKKYQKSRYS-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------

----------------------DQAG---LELTEIRLLLPP--------ERVPPPPAKEA
AKNGDLEEALKLFILAKDIFPTKKVVSRIQKLQEALEQLAED----G--DEDDEFIDVCN
SGLLLYRELYEKLFEHQKEGIAFLYSLHKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNRVLLIMPTSLINTWVKEFAKWTPGMRVKTFHGSSKDERTRNLTRIQQRNGVIITTYQ
MLINNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 504)

TKRADNPKARLSEKNLGVEAIGEMPSLTRKNDFIVWVRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARVCHLLNLGTATFSVQDENEQEVA
SDVDS--IGHLTDNALMQESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMALLERLQDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTVGDLQNSATQMQLQSLHAAQRRSDEKLDEHIAYLHSLGIAGISDHDLMFT
RDLSVKEEL---AAVEDSPYIQQRVQKAQFLVESESQNT---MERQRTGNEEAWLKAYAF
PSQQ-KKGP-ALHKPQPRPSSLLT-NPT-------------QAEDISSQMASISIYDQSA
ESEPQD-D-SKAHDVTLLQG-------------DQHHREGTFDAGSVATSPQGAG----S
IGGVWNDSLLGPTKCFAAESEAVQKQALQASPGQEALPEN-------LLGSFNYLPTQPI
NADPEPD--VNLEDSVLSYHCS------------PTANENQNI----ESDVHMIEISD--
VLSASPSALQG----AQASE---AQL------GLEEDLLESPPQYACDFNLLLEDS-TGT
RQSLSSKFLEHVEK----------ENSLQSPAANSRAESAL--------------NLSLD
SSNKSDEEPEVIS-V-KTRSKARR-ILSDDE--DEEDAFKGTSGT---SSFSISPFQFSS
VKQFDVSTPKNDANPSARFFSPKIPDSVNTSFN-----SRRSLASRKSLINVVLDDMEDM
EERLDDS---------SEEESARGHSEE---ESSDEASAGTEENPSGETQASENKPSSLT
VSEPSS-----LVLKSSPCTS---EPLS-SDPLVDPPQDP-------A-VETANDYETLV
ARGKELKECGKVQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNT

----------------------MVSFLSLYLQCP--AYSKCLS----LSVYRYVKEAKEA
TKSGNIEEALKLFYLAKAIYPNDKVLSRIQRLQEALEELSVE--------ETDDFVNVCN
SGLMLYGELHD

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 297)

RLFEYQKEGVAFLYSLYKDKRKGGILADDMGLGKTVQIIAFLSAMFDAE
LVRHVLLIMPSSLISTWVKEFAKWTPGMRVATFHGSSKSERTKNLTRIQRKSGVAITTYQ
MLINNWQQLSQMDGKEFVWDYLILDEAHKIKSSSTKSSKIARCIPVKNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 492)

IQNN
LYELWSLFDFACQGSLLGTSKTFKMEYENPIIRAREKDATIGEKALGFKISENLMTLIKP
YFLRRTKEDVQKKSANNKQSSLPEKDPGGADFCEMPSLSRKNELIIWVRLVPLQEEIYRK
FVSLNHIKQLMIETRSPLAELNVLKKLCDHPRLLSARVCSLLGLKGSSLSGGDESQLV--
--HSDIQMDQI

PF11496 // ENSGT00590000083118_0_Domain_2 (492, 647)

PHDSLMQESGKVIFLMALLKRLQDEGHQTLVFSQSRKLLDIIEHLLKAE
HFKTLRIDGTVTHLSERQRRIDLFQQSRGVSVFLLTSQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLVRQTTGDKKNPFRYF
TKQELRELFTLGDFRSSATQLQLHSLHAGHRKTDKKLEEHIAYLHTLGIAGISDHDLMFT
HDIP--EEL----EEGQSQYIQERVQKAQLLVELESQNNELLMSNIKSGIDETWLKEATS
-SRPKKKGP-EFNVLH-HLSPPI-IDLV-------------QEDSLRSGIATLNITEDS-
KTCD---LSGMDVDMSVKQS-------------GVDVPEHKADDELRTT------FSSEE
GHEMEISKTSHPNES------HISIDTTQDSVKQLVQEIA--------------------
KADAEPNPD-Q------IIPIS--------------------PEKSLKLGTSINM--S--
TCP---SA-----------WENSG----PNQSRLGKESLVSSLQNIGDFNLFLEDS-LGS
DQNLSNLPLEPTER----EN-------------ITWELADNPEGKSSSVRSLQLDDC---
-SDRESELEDEIICV-KTRYKANK-IVSDDDD---DSVIE----------GMLSPL-PNP
LLTQFSSTPKSNRSQSELFFSEMCSGGNNS-AI-----ARRSLASRRSLINVVLDHVEDM
EEDACE------------PKKEP----------------------TEETPLFQREACSLP
GAHTDSAPGA--SNKDSQE---------------------MPEHNPSSAAEATDEYETLV
RRGKELKESGKTQEALNCLLKALDIQSTDPQVMLMTLNLYKLLNQ-

------------------------------------------------------------
-----------LFRLAPAIRPSEKLQGRMQRVQEALAAAEQQQQEEQEEEEDEGFVDVCG
SGLLIYGEMHG

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 296)

KLFQHQREGVAFLYRLHRDGKPGGILADDMGLGKTIQVIAFLSGMFDAE
LVQHVLLVMPTTLVSSWLAEFARWTPGLRVKEFHGTSKTERTRNLERVQRKNGIVITSYQ
MLINNWKQLASRHEQEFVWDYVILDEAHKIKCPSNKTTKCVYAIPARHRVLLTGT

ENSGT00590000083118_0_Linker_1_2 (296, 537)

PVQNN
LREMWSLFDFACQGSLLGTAKTFKMEYENPITRAREKDATPGEKALGLKMSENLMAIIKP
YFLRRTKEDIKSNHADKVDTPLPED-PSENKGPVMPSLTRKNDFVVWVYLAPVQEEIYRN
FLCLDHVKEVLTTTRSPLAELTVLKKLCDHPRLLSARACIQLGLEEQEGSEQDDRIEA--
---GMSKIDHLSDETVIQESGKMQFLVGLLERLREEGHRTLVFSQSRKMLDIIELV

PF00271 // ENSGT00590000083118_0_Domain_2 (537, 615)

LCRR
QFRVLRIDGTVTQLTERERRINAFQSNPDYSVFLLTTQVGGVGITLTAASRVVIFDPSWN
PATDAQAVDRAYRIGQKENVVIYRLITCGTVEEKIYRRQVFKDSLIRQSTGDKKNPFRYF
SKQELRELFTLEDPRTSATQIQLQSLHAMQRKSDLQLDEHLAYLHSLAMFGISDHDLIYT
RETAHE---EKVESEEAHQYIQRRVQKAHELVQLESQLRDQRMEGIRNACEENWQRPLGS
VSGPKKLPP-GLNDKNNFVSPPVADAHKKDNVIDLTED-EAQVLDVSTKMTTLTVDDLDE
EELAQD-VSGMETEVLN-------TSKTAEQ-SDIQESEQNPESSITPSSPALESQSLQE
KQ----HSHIHSDSSA-----KARNDLAGHCQKQHIHSDS-SAKARNDLAGHCHNSSEAG
MA-----RLED-------------------------------PRRDAELS--VLSLSN--
VTTEINAE-----------LHKSHMLED-----SLEGTSAPSLQDQVDFNLVLEES-DEG
WQDA-SNREESVEH-PEKESLQLQAESLCKSPDKESPNKALPSEPSSHGTAEEEPNASLQ
GSEPLDESSCLFTFT-RK-RRLNR-IASPSDSEG--------QPEQVPSSPLDSTQ-HGL
PERISASTPKHDTRRAKAIFSPQLN------NS-----GNRSNASRRSFINRLVDEVEDI
GEIM---GTTDEEDSDDGDEEQDGLVEDEA-EECTGESAEPEEEPTGETLDTNS----VE
SEQS-EAEETESSQEESTGDA----ELQSGEHIDYFTQESTSAKGTGQSSSPAADYDTLV
HSGKKLQNDGKLQEALDCFLQALDIKSGDPEVMLLTLNLYRQLAQK

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSGQSLEHVEK----------EKSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

----------------------MEVY---RGLAEAETLSSEQAAR----YLRYVKEAKEA
TKNGDLEEALKLFSFAKDIFPNEKLMSRINKLQEALEELEEH-------ED-DEFTDVCN
SGLLLYRELYNQLFEHQKEGVAFLYSLYK

PF00176 // ENSGT00590000083118_0_Domain_1 (150, 379)

DRRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLISMWVKEFAKWTPGMRVKTFHGPSKDERTRNLNRVQQRNGVVITTYQ
MLINNWQQLSSCNGQAFVWDYVILDEAHKIKSSSTKSAICARAVPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIVRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQKTKSNIP

ENSGT00590000083118_0_Linker_1_2 (379, 503)

KVRPTENNSGIDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSTRVCRLLHLGTAKISGQDGNEE-DS
SDVDA--IAHVTDDTLMKESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLIDLLKRLRDEGHQTLVFSQSRQILNIIERLLRNE
HFKILRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKGSLIRQTTGDKKNPYRYF
SKQELRELFTVEDLQNSVTQLQLQSLHAAQRRSDKTLDEHITYLHSLGIAGISDHDLIYT
RDLSVKEEL---DVIEESQYIQQRVQKAQFLVELESQNT---VEKQRTGNEGTWPVAPLF
FSQAQKKCP-ELKKPQHWPSPLTTTHPT-------------QEGVISFQMANLSTED---
----QD-FSSIKMHMTMIQD-------------SMHSSENTFHTDSVATLPKEFG----T
VEEIWTDSLQGTVKSFAVENEALQKKSLQEEPEQDALQEN-------SLGSLNYLTSQSI
KADLAPN--LDLQDDEILHHNG-------LWPSNPITNENQTT----KSNISVIEISN--
ESSASHSVLQG----AQANE---AKS--------EGEPLASLPQYACDFNLFLEDS-ADN
TQNLSTQSLEYVEK----------ENSLCGSAAKSSAESVH-----------S----NLD
SSKKDNDPEEVVVNV-KNRSKARR-IISDDEGEDD--SFKGTLST---SPFSTSLCQFSS
VKQFDASTPKDD-SLPGRFFSPKISDSINKSVN-----PRRSLASRRSLINVVLDHVEDM
EERLDNS---------SKAEGTGDDLEEGAEESSDKASEHTE-DPSAERLFAENKSGGLT
VSKPLG-----SSLLTSPGAP---DPLS-AGPMVDSPQDN-------A-MEAANDYETLI
TRGKELKQCGKIQEALNCLVKALDIKSSDPEVMLMTLSLYKQLSNT

-----------------------------------------------------MKEAKEA
TKNGYLEEALKLFNLAKDIFPTEKLMSRIQKLQEALEELK-H-------EDDDEFTDVCN
SGLLIYRELHNQLFEHQKEGVAFLYSL

PF00176 // ENSGT00590000083118_0_Domain_1 (148, 372)

YRDRKKGGILADDMGLGKTIQIIAFLSGMFDSS
LVNHVLLIMPTNLISMWIKEFAKWTPGMRVKTFHGPSKNERTRNLYRVQQRKGVVITTYQ
MLINNWQQLSSFNGEAFVWDYVILDEAHKIKSSSTKSALCARAVPAHNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLRTFKMEYENPIVRAREKDATPEEKALGLKISENLMEIIKP
YFLRRTKEVVQ

ENSGT00590000083118_0_Linker_1_2 (372, 502)

RKKSSILEVRPTEENSGGDAICEMPSLSRKNDLIIWVRLVPLQEEIYRK
FVSLDHIKELLLETRSPLAELGVLKKLCDHPRLLSTRACHLLQLRTAKISAQDGNED-HS
SDMDD--ISHVTDDLLMKESG

PF00271 // ENSGT00590000083118_0_Domain_2 (502, 615)

KMMFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLRNK
HFKTLRIDGTVTHLLEREKRINLFQHNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PASDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKGSLIRQTTGDKKNPFRYF
NKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKTLDEHITYLYSLGIAGISDHDLIYT
HDLSVKEEL---DVIEESQYIQQRVQKAQFLVEFESQNT---MEKQRTGNEGVWPTTSLF
YSQTKKKCP-ELKKPQPQLSSL-TTNPT-------------QEEAVSFQVASIHIED---
----QE-CPSVNMHRTTLQD-------------SVHLCGSTVHTDSVATLSKEFG----S
IEEIWAASLLETTKSFAVENESLQK-SLQEEPEQG-------------------------
-ADLALR--VDAQDDEILYH------------SNSITDENKNV----KLNISVIEIAD--
ESAAADSVLQG----AQANE---AKS--------EGEPVASSPQYACDFNLCLEDY-ADN
TRDLSTQSLECVKK----------ENGLCGSTANSRAESVH-----------SEACLSLD
FSKKDNDPEEAVVSI-KSRSKARR-IISDDEDEDA--SFKGPLHA---SPFNTSLFQFSS
EKQFDASTPKDD-NLPGRFFSPKIPASVNQSIK-----PRRSLASRRSLINVVLDHVEDM
EERLDGS----------EAEGSKGDLEEGAEESSDSASEKTE-DASGERLSSENKSVELT
VSEPLG-----SGLQSSPGMP---DPLS-AGPMVDSPQDK-------T-TEAENDYETLI
TRGKELKECGEIQEALKCLVKALDIKSSDPEVMLMTLSLYKQLSNT

--------------------------------------------Y----FYRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------GD-DEFIDVCN
SGLLLYQELHNQLYE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 373)

YQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISIWLREFVKWTPGMRVKTFHGPSKDERTRNLCRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFLWDYVILDEAHKIKTSSTKSAICARAIPASNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLRTFKMEYENPITRAREKDATPQEKALGFKISENLMAIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 536)

KKSSNPEAQLSEKSPDVGAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGAAKFSVQDEIEGEDS
SDVDH--IDQISDDTLMEESGKMVFLMDLLKKLRDEGHQTLVFSQSRRILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTITHLVEREKRISLFQQNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHAAQRRSDKNLDEHIAFLHSLRIAGISDHDLMYT
RDLSVKEEL---DVIKDSHYIQQRVQKAQFLVECESQNTELLMERQKTGNEGIWLREPVY
Q--TKKKHP-EVNKPQPQPSSRLPIYHT-------------QEEEISSLMASVIIDDLPK
EGE-KD-LSRTKMNDTILQD-------------GKHPCVSTFDDDFVTSLPKGCG----D
VEEIFPDSLSGM---------ALQKEASQEGFMQESEQES-------PLGSFNYLPSKSA
SVDLGPN-LDQLEDDEILHHCN-------PSPANPKTKEYQRP----ESNVSVIKIAD-D
DLAAAHSALQD----AQTNE---AKL--------EEEPLASSAQYACDFNLFLEDS-ADN
GQNLSSQFLEHVEK----------ENSLCGSAANSRAESVH-----------SKACLSVD
LSEEDDEPE-I-VYV-KIRRKARR-IDSDDEGEH---TFKDTSST---NPFNTSPFPFLS
VKQFDASTPKNDISPPGSFFSPKISESINKSVN-----SRRSLASRRSLINVVLDHVEDM
EERLDNS---------SEAKVVEDNLEEGAEESGDEAPEHTKEDPSRETLSSENKSSQLS
TSKPGA-----LAQETSPGDP-E--PLS-GGQLVDSPQDE-------A-MEAVNDYDTLV
LHGKELKECGKIQEALDCLVKALDIKSSDPEVMLMTLSLYKQLNKT

----------------------MEAS---QGLAEVGTLSPQLAES----YLRYVQEAKEA
AKNGDLEESLKLFNLAKEIFPTKKVMSRIQKLQEALEQLAEE-------EDDDEFIDVCS
SGLLLYRELYEKLFEHQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVNEFAKWTPGMRVKTFHGSSKSERTRSLTRIQQRNGVVITTYQ
MLLNNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAVCARAIPASNRLLLTGTPVQNN
LQELWSLFDFACQGSLLGTLKTFKMEYEHPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 503)

TKKADNPEARLGEKNPAGEAICEMFSLARKNDLIVWIRLLPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACRLLNLGTATFSAQDENEQEDV
SNMNS--IDHLPDKTLIQESGK

PF00271 // ENSGT00590000083118_0_Domain_2 (503, 615)

MIFLMSLLERLQDEGHQTLVFSQSIKILNIIERLLKNK
HFKTLRIDGTVTHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
TKQELKELFTVGDLQNSATQMQLQCLHAAQRRSDEKLDEHIAYLHLLGIAGISDHDLMFT
RDLSVKEEL---DMLEDSQYIHQRVQKAQFLVESESQNT---VQRQTTGIEETWLKAQEF
PSQQKKKGT-EFNKPQPQPSRLLT-KPT-------------QVEAISSQMASITICDQSA
ESEPQE-H-SEVHD-VTSLQ-------------GCHHFNSTSEAGTIASLPQGAE----S
IGEVSTDSLLSPAKGFAAENDAMQKKGLQASPGQEAPSEN--------LGSFHYLPRESS
KANLGPN--LDLQDSVVLYHHS------------PTANENQNL----ESDVPMIEISD--
DLSEPPSALQG----AQAIE---AQLELKED-----DPLKSPPQYACDFNLFLEDS-ADT
RQNLSSKFLEHVEK----------EKSLQSPAANSRAKSAL--------------TLSLD
SS-KSDEESEVIS-V-KTKSKTRR-ILSDEEDE-DEDAFKGS-HT---NSINISPFPFSS
VKQFDASTPQSGSNPSRRFFSPKIPGEVNTSLH-----SRRSLASRRSLINVVLDDVEDM
EERLDNS---------SEEESEPGLSEE---NNEEEALACTEEQPSGATLASGNKSSNLT
MSEPTS-----PAPQSSPCAP---EPSS-SDPMPDPPQDP-------A-VEAGNDYESLV
ARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNI-

----------------------MEAS---QGLAEVEALSPQLAAS----YLRYVQEAKEA
AKNGDLEEALKLFNLAKDIFPTKKVVSRIQKLQEALEQLAEE----EEEDDDDEFIDVCS
SGLLLYRDLYEKLFEHQKEGIAFLYSLYKDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNRVLLIMPTSLINTWVKEFAKWTPGMRVKTFHGSSKDERTRNLTRIQQRNGVIITTYQ
MLINNWQQLASFNGQEFVWDYVILDEAHKIKSASTKSAICARAVPASHRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPIIRAREKDATPGEKALGLKISENLMEIIKP
YFLRRTKEEVQ

ENSGT00590000083118_0_Linker_1_2 (372, 504)

TKKADNPEAGLSEKNLGVEAICEMPSLTRKNDFIVWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARVCHLLNLGTATFSVQDENEQEVA
PDVDS--IHHLTDNALMQESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLVALLERLQDEGHQTLVFSQSRQILNIIERLLRNR
HFKTLRIDGTITHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTVGDLQNSATQMQLQSLHAAQRRSDEKLDEHIAYLHSLDIAGISDHDLMFT
RDLSVKEEL---AMVEDSPYIQQRVQKAQYLVESESQNT---MERQRTGTEEAWLKAYSF
PSQQ-KKGP-ALNKPQPQASRLLT-NPT-------------QVEDISSQMASITIYDQSA
ESEPRD-D-SKAHDVTLLQG-------------DQHHCESAFDAGSVATSPQGTA----S
IGGVWTDSLLGPTKCFAAESEAVQEKALQASPGQEALPEN-------LLGSFNDLPTQSI
KADPGPN--LNLEDSVLSCHCS------------PTANENQNI----ESDVHTIEISD--
VLSASPSALQG----AQASE---AQLEVRPQLELEEGLLESPPQYACDFNLLLEDS-TGT
RQSLSSKFLEHVEK----------ENSLQSPAANSRAESAL--------------NLSLD
SSNKSDEEPEVIS-V-KTRSKARR-ILSDDE--GEEDAFKGPSGT---SSFSISPFQFSS
VKQFHVSTPKNDANPSARFFSPKLPGSVNTSFN-----SRRSLASRKSLINVVLDDMEDM
EERLDES---------SEEESARGHSEE---ESSDEAIACTEEDPSGETQASGNKPSSLT
VPEPTS-----LALESSPCAP---EPLS-SDPLVEPPQDP-------A-VEAANDYETLV
ARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNNS

----------------------MEAS---RGLVEAEALSPEQAAH----YLRYVKEAKEA
TKNGNLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEELAGN-------GD-DEFTDVCN
SGLLLYRELHNQLFEHQKEGVAFLYNLYKDGR

PF00176 // ENSGT00590000083118_0_Domain_1 (153, 373)

KGGILADDMGLGKTVQIIAFLSGMFDAS
LVNYVLLIMPTNLINTWVKEFVKWTPGMRVKTFHGPSKYERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKMSENLMAIIKP
YFLRRTKEEVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNLEVRLSEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELAVLKKLCDHPRLLSARACHLLNVGTVTFSTQDENDGEDS
PDMDH--IDKITDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNS
HFKTLRIDGTITHLLEREKRINLFQQDKNYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSIIRQTTGEKKNPFRYF
SKQELRELFTVEDLQNSVTQLQLQSLHAAQRRSDKKLDEHIAYLHSLGIAGISDHDLMYS
CDLSVKDEL---DEIEESQYIQHRVQKAQFLVELESQNTGFLVEQQKTRNEGAWLREPVF
PSKTKKKCP-KLNKPQLPLSPLITTCHI-------------QEEDISSQTAGIIVDDLPK
EGEKQD-LASIK-NITVLQD-------------GRHLCKSTFDADSIAALPKGFG----S
MEEIWTDSLLGMAKSFGTKNEALKKEALQERSKQEALQEN-------PPESFNYLLNKSA
KADIGPN-LDQLKDDDILQHCC-------PWPIIPITNENKNT----ELNVSVIEIAD--
NLSASHSALQD----AQANK---AEL--------EEEPSTCLPQYACDFNLFLEDS-ADN
GQNPSSLSSEHVEK----------ENSLCGSAANSKAESVH-----------SKACLSWN
LSEKDDETEEVVANT-KIRRKARR-IVYEDEDED--DSFKGISST---NLFNTSPFQFSS
VKQFDASTPKSNISLPGRFFSPGVSSSVNKSIN-----SRRSLASRRSLINVVFDHVEDM
EEGFDNS---------SEDKGAEDYPEEGAEESSGEASECSEKDPSGEILSEENKSSWLS
MSKPSA-----LAQETSPGDP-E--SLS-GKELVDSPKDK-------A-VEAANEYETLV
IRGKELKECGKLQEALNCLVKALDIKSADPEVMLLTLSLYKQLNT-

----------------------MEVS---TGFAEAQALSPEQTAH----YLRYVKQAKEA
AKNGDLEEAFKLFSLAKDIFPNAKVLSRMKKIQEALEELAEH-------GD-DEFMDVCN
CGLLLYRELHNQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAA
LVNHVLLIMPTNLISTWVKEFVKWTPGMRVKAFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKTSSTKSATCARAIPAKNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMQYENPIIKAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQEKKLSNPEIRHSKKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACCLLNLKGSKFSSQNENEGEGS
SDVGH--IDQVTDATLINESGKMIFLMELLKRLRDEGHQTLVFSQSRQILNFIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

VLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQIFKDSLRRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSATQLQLQSLHADQRRSDKKLDEHIAYLHSLGIAGISDHDLIYT
HDLAVKEEL---VEIEESQYIQQRVQKAQFLVEFESQNTELLMERQRTVNEGAWPREPVF
PPRAKKKCP-ELKKPQFWPS----AHHT-------------QEEDISFQMANVIIDDVAE
GSGKQD-LSSIKDNSSDLQD-------------DRHTCEDNFDAEFAATLPRGYG----G
TEEICADSLLEVTKSFTTDSEALQKEAL---------QEN-------PPGSLNYLLNESV
GTDLEPN-LDQLKDDEILQPIN-------P-----TT--NKNT----DVNTSIIEIND--
DLSASHRPLQD----SQANE---AQS--------EEELSASPPQYACDFNLFLEDS-ADN
GQNFSHQSLKHAEK----------ENSLCSSTANSRAEFVS----------NNKARLSLD
FSERDDGPEEVVVNV-KIRSKARR-IVSDGEDEDN--SFTGISST---NPLDTSLFPFLS
------STPKNGISPPQRFFSPKMADSGNKTIN-----SRISLASRRSLINVALEHVEDM
EERLDNS---------SEEKSIEDYLEEGTEGSSGEASEYTDEDPSREKLSSENKSSCLT
TSKLGT-----TAQETSTDDP-E--PLS-GKQSLDSPQNE-------A-LEDVNEYETLV
MRGKELKECGKIQEALNCLVKALDIKTADPEVMLMTLSLYKQLN--

----------------------MEAS---RGFAEAGALSPEQAAR----

PF00515 // ENSGT00590000083118_0_Domain_0 (50, 83)

YLRYVKEAKEA
TKNGDLEEALKLFNLAKDIFPN

ENSGT00590000083118_0_Linker_0_1 (83, 136)

EKVMSRIQKIQEALEELAEH-------GD-DEFTDVCS
SGLLLYRELHNQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

YQKEGVAFLYSLYRDGRRGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISTWLREFVKWTPGMRVKTFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSSNGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSNPDIQLSEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACHLLNLGAVNFSAADENEGEDT
SDVDH--IAQISDDTLMGESGKMIFLMDLLKRLRDEGHQTLVFSQSRRILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
CFKILRIDGTITHLVEREKRISLFQQNKDYSVFLLTTQVGGVGLTLTAASRVVIFDPSWN
PATDAQAVDRVYRI

ENSGT00590000083118_0_Linker_2_3 (615, 1376)

GQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
SKQELRELFTIGDFQNSATQLQLQSLHAAQRRSDKSLDEHIAYLHSLSIAGISDHDLMYT
HDLSVKEEL---DVIEDSHYIQQRVQKAQFLVETESQNTELLMERQRTGNEGVWLREPIF
PSQTKKKCP-EFNKPRPQPSPFLLTHHT-------------QEEEISSQMASVIIDDLPE
ESKKQD-LSSIKTNVTIPQD-------------GRHPRESTFDADFVASLPKGCG----N
VEEMWTDSSSGT---------ALQKELSREGPSQEAPQES-------PLGSANYLQSKSV
RADLGAN-LDQLEDDEIFHHCT-------SWPANPTTKEYQSR----ESNVSVIKIAD-D
DLSASYHALQD----APENE---AKL--------EEEPLASSPQYACDFNLFLEDS-ADN
AQNLSSQSLERVEK----------ENSLYVSAANSRPESVH-----------SKARLSVD
LSEKDDEPEEEVVNV-KVRSKARR-INSDDEDEGD--TFKDTSSP---NPFSTPPFPSLS
VKQFDASTPKNDLSPPGSFFSHQISNSINKSIN-----SRRSLASRRSLINVVLDHVEDM
EERLDSG---------SEAKAAADYLEEGAEESSSEALEAT-EDPSRETLPSENKSSQLS
SPMPGA-----PGQEASPGDP-E--PLS-GEQLVDSPQDE-------A-VEAAND

PF00515 // ENSGT00590000083118_0_Domain_3 (1376, 1409)

YETLV
LRGKELKECGKIQEALNCLVKALDIESSDPEVMLMTLSLYKQLNKT

------------MEASRRFPEAEA-----L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQVTDDTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYT
CDLSVKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRTRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLLSTHHT-------------QEEDISSKMASVVI-DLPE
EGEKED-LSSIKVNVTTLQD-------------GK----GTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADIGPN-LDQLKDDEILRHCS-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEEPSASSPQYACDFNLFLEDS-ADN
RQNFSSQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSSI---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGPEDYPEEGVEESSGEASKHTEEDPSGETLSSENKSSWLM
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQDK-------A-AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------MGWMTRDPQDLGIN---LGQDVVAYCFLGCGVW----HQRYVKEAKEA
AKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEALAEQ-------GD-DEFTDVCS
SGLLLYRELHDQLFEHQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 379)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWLKEFVKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFLWDYVILDEAHKIKTSSTKSAICARAVPASNRLLLTGTPIQNN
LRELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKK-TSNP

ENSGT00590000083118_0_Linker_1_2 (379, 506)

DVKLNEKNPDVDAIYEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACGLLNLGTVTFSAQDGNEGEDS
SDMDH--IDQITDDTLMEESGKMIF

PF00271 // ENSGT00590000083118_0_Domain_2 (506, 615)

LMGLLKRLRDEGHQTLVFSQSRQILNIIEHLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEF---DVVEESHYIEQRVQKAQFLVEFESQNKEFLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTHYT-------------QEEDISSKMASVVIDDLTE
EGEKQD-FSSIKMNVTTLQD-------------GRHPCESTCSADSIATLPKGFG----S
VEELFTNSSLGMEKSFATKNEALQKETLQEGPKQEALQED-------PLGSFNYLPSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DFSASHSVVQD----AQANE---AKL--------KEEPSASSPQYACDFNLFLEDS-ADN
RHNLSSQSSEHVEK----------GNSLCGSAANSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKAGR-IVSDGEDED--DSFKDTSNT---NPFNTSLFQFSC
VKKFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLSSRRSLINMVLDHVEDM
EERLDDS---------SEAKGDEDYPEEGAEESSGEASECIEEDPSGETQSSENKSSWSM
MSKSSA-----VAQETSLGSP-E--PLS-GEQLVGSPQDK-------A-AEAANDYETLV
KRGKELKECGKLQEALNCLVKALDIKSADPEVMLLTLSLYKQLNT-

----------------------MEAS---GRFVEAAALTPEQAAL----YQRYVKEAKDA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKIQEALEELAEH-------ED-DEFTDVCN
SGLLLYRELHN

PF04851 // ENSGT00590000083118_0_Domain_1 (132, 297)

QLFEHQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAT
LVNHVLLIMPTNLISTWIKEFVKWTPGMRVKTFHGPSKDERTRNLSRIQQRNGVIITTYQ
MLINNWQQLSSLNGQEFVWDYVILDEAHKIKTSSTKSAICARAVPARNRILLTGTP

ENSGT00590000083118_0_Linker_1_2 (297, 536)

IQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKKKSSTPEVRLSAENPDVGAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACHLLNLGSVQFSVQGENEGEDS
SDVGH--IDQITDDALMEESGKMVFLIELLKRLRDEGHQTLVFSQSRQILNIIEH

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTVTHLVEREKRINLFQQNREYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGDKKNPFRYF
TKQELRELFTIEDFQHSATQLQLQSLHAAQRRSDKILDEHIAYLHSLGIAGISDHDLMYT
RDLSVKEEL---DVIEESHYIQQRVQKAQFLVELESQNTELLTGRQRAGNEGTWLTEPLF
SSQMKKKCS-ELNKLQPRHSLLLPTYHT-------------QEEEISSQMASVIIDDLPE
ESENQD-ISSIKMNVTVSQD-------------GSHPPERTSDAGSVAALPEGYG----S
VDEIWTNSL-GM---------VLQTEALQEGPTRGTLQEN-------PLGDFNFLPSKAV
GADLGPD-PKQPNAAETLPHCN-------LWPVSPMTLESQ-T----EPNTSVIRRAD-G
DLSASHSVLQD----TQANV---TKL--------EEERIASSSQYACDFNLFLEDS-ADS
RQNLSRQSSQHAED----------EKSLCGSAAHSQAELEW-----------DKAHLSVD
LLETNDEPEEVVGNV-RGRRKARR-IISDGEDEDD--TFKDTSST---DALTTSPFLFLP
MKQFDASTPKSDISPSGRFFSPNIPDSVSKSLH-----PRRSLASRRSLVNVVLDHVEDM
EKEPDSS---------SGAEAAAGDSKEGAEESSGEASESTE-GPPGE------TL----
PSENES-----SRLTSPPGDP-E--PLS-SGQSRDSPQKE-------A-AESGTDYETLV
IRGKELKERGQIQEALNCFVKALDIKSADPEVMLMTLSLYKQLNKI

------------MEASGRFPEAEAL-------------SSEQAAR----YLRYVKEAKEA
AKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEVL-ELAEQ-------GD-DEFTDVRN
SGLLLYRELHDQLFEHQKEGVAFLYSLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 378)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLMNTWLKEFVKWTPGMRVKTFHGPSKDERTRNLNWIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFLWDYVILDEAHKIKTSSTKSAICARAVPASNRLLLTGTPIQNN
LRELWSLFDFACQGSLLGTLKTFRMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEEVQKK-TSN

ENSGT00590000083118_0_Linker_1_2 (378, 506)

PDVKLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGILKKLCDHPRLLSARACGLLNLGTVTFSAQDGNEGEDS
PDMDH--IDQITDDTLMEESGKMIF

PF00271 // ENSGT00590000083118_0_Domain_2 (506, 615)

LMGLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKILRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRNRNEGAWLREPVF
PSST-KTCP-NLNKPQPQPSPLISTHDT-------------QEEDISSKMASVVIDDLTE
EGEKQD-LSNIKMNATTLQD-------------GRHPCESTCSADSIAALPKGFG----S
VEELFMNSSLGLEKSFASKNEALQKETLQEGPKQEALQED-------PLGSFNYLPSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNISIIEIAD--
DFSASHSVLQD----AQANE---AKL--------KEELSASSPQYACDFNLFLEDS-ADN
RQNLSSQSSEHVEK----------GNSLCGSAANSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKAGR-IVSDSEDED--DSFKDTSNT---NPFNTSLFQFSC
VKKFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----LRRSLSSRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEAAVESSGAVSECTEEDPSGETQSLENKSSWSM
MSKSSA-----PAQETSLSSP-E--PLS-GEQLVGSPQDK-------A-AEAANDYETLV
KHGKELKECGKLQEALNCLVKALDIKNADPEVMLLTLSLYKQLNT-

---------------------------------------------------RYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVMSRIQKLQEALEELAD--------GD-DEFTDVCN
SGLLLYRELHNQLFE

PF00176 // ENSGT00590000083118_0_Domain_1 (136, 454)

HQKEGVAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTSLISTWVKEFVKWTPGMRVKTFHGPSKDERARNLSRIQQRNGVIITTYQ
MLINNWQQLSTLNGQEFVWDYVILDEAHKIKSSSTKSAICARAVPASNRILLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKIEYENPITRAREKDATAGEKALGLKISENLMAIIKP
YFLRRTKEEVQKKKSSNSEVRLSEKNLDVNASYEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRL

ENSGT00590000083118_0_Linker_1_2 (454, 536)

LSARACHLLNLGAVRFSAQDENEGEDS
SDVDHIHIDQITDDTLMKESGKMIFLLDLLNRLRDEGHQTLVFSQSRQILNIIER

PF00271 // ENSGT00590000083118_0_Domain_2 (536, 615)

LLKNR
HFKILRIDGTITHLVEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIYDPSWN
PATDAQAVDRVHRIGQKENVVVYRLITCGTVEEKIYRRQVFKESLVRQTTGDKKNPFRYF
SKQELRELFTIEDFQNSVTQLQLQSLHAAQRRSDKKLDEHIAYLHTLGIAGISDHDLMYT
HDLSVKEEL---DVIEESHYIQQRVQKAQFLVESESQNTELLMERQRSRNEGIWLREPVF
PSQTKEKCP-QVNKPQPQPSSFLTTHYT-------------QEEEISSQMASVIIDDLPE
ESEKYC-LSSVKTNVTIVQD-------------GRHPHESTFDADFIAMLPKGCG----S
VEEICTDSLLGM---------ALQKEAPQEGTTQEA------------LQSFNYLLSKSV
RADRGPN-IDELKDDEILHQCN-------PWPTNPITDENKNT----ESDASVIKIAD-D
VLSASHSALMD----AHPNE---ATL--------EEEPLESSPQYVCDFNLFLEDS-ADN
GQNPSSQSFEHVEK----------ENSLCGSATNSGVEFVH-----------SKAGLSMD
LSEKDDES-EVVVNL-RVRSKTRR-IVSDGEDEHD--TVKDTSST---NPFSTSPFQFLS
VKQFDASTPKNDISPPGRFFSPKIPDSINKSVN-----SRRSLASRRSLINVVLDHVEDM
EERLEYS---------SEAKVAEDSLEERAEESSGEASEGTEEEPFRETLSSESKSSWLS
TPKSGA-----VAQETSPGDP-G--PLS-SGQLVDSPQDK-------A-VEAVNDYETLV
MRGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNTT

------------------------------------------------------------
-----LEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 372)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQ

ENSGT00590000083118_0_Linker_1_2 (372, 504)

KRKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEDS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVL
PSSTKKKCP-KLNKPQPQPSPLISTRHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVSTLQD-------------------GTCSADSIATLSKGFG----S
VEELCTNSSLGMEKSFT----------LQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHRN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSGQSLEHVEK----------ENSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLI
KRGKELKERGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

------------MEASRRFPEAE--A---L--------SPEQAAH----YLRYVKEAKEA
TKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQ-------GD-DEFTDVCN
SGLLLYRELHDQLFEHQKEGIAFLYRLYRDG

PF00176 // ENSGT00590000083118_0_Domain_1 (152, 373)

RKGGILADDMGLGKTVQIIAFLSGMFDAS
LVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQ
MLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNN
LQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKP
YFLRRTKEDVQK

ENSGT00590000083118_0_Linker_1_2 (373, 504)

KKSSNPEVRLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRK
FVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGT--FSAQDGNEGEGS
PDVDH--IDQITDNTLMEESGKM

PF00271 // ENSGT00590000083118_0_Domain_2 (504, 615)

IFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR
HFKTLRIDGTITHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWN
PATDAQAVDRVYRIGQKQNVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYF
SKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDTKLDEHIAYLQSLGIAGISDHDLMYT
CDLSIKEEL---DVVEESHYIQQRVQKAQFLVEFESQNKELLMEQQRNRNEGAWLREPVF
PSSTKKKCP-KLNKPQPQPSPLISTHHT-------------QEEDISSKMASVVIDDLPE
EGEKQD-LSSIKVNVTTLQD-------------GRHPYEGTCSADSIATLPKGFG----S
VEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQED-------PLESFNYVLSKST
KADLGPN-LDQLKDDEILHHCN-------PWPIISITNESQNA----ESNVSIIEIAD--
DLSASHSALQD----AQASE---AKL--------EEERLASSPQYACDFNLFLEDS-ADN
RQNFSDQSLEHVEK----------EKSLCGSAPNSRAGFVH-----------SKTCLSWE
FSEKDDEPEEVVVKA-KIRSKARR-IVSDGEDED--DSFKDTSST---NPFNTSLFQFSS
VKQFDASTPKNDISPPGRFFSSQIPSSVNKSMN-----SRRSLASRRSLINMVLDHVEDM
EERLDDS---------SEAKGAEDYPEEGAEESSGEASKYTEEDPSGETLSSENKSSWLT
TSKPSA-----LAQETSLGAP-E--PLS-GEQLVGSPQA----------AEATNDYETLV
KRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN