Query Results 

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLMIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVVA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------MS----------DQXXXXXXXXXXXXXDSK--TPKQDFQPVKRSCTDVFCCV
LFI----LFIGAYIILGLVAWVHGDPRRVAYPTDSKGHFCGQKGTPNENKTILFYFNLFS
CTSPSVVLNLQCPTTQXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
SLTQILLDDDCPTAIFPSKPXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXTVSKILDARTVGMKVFEDYATTWYWILIGLTIAMLLSWLFVILLRYTAGLIFWLFML
GVISVIGY-GAWHCYREYTHIR-----DKPSSQSDVYNIGLQSDISMYFKLKQAWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

GLMI
VLCVIEVLIIVTLIFLREKIRISIALLKEGSKAIGHIPTTLIYPFLTFIFISICICYWAV
IAXXXXXXXXXXXXXX----XXXXXXXXXX-XXXXXXTF--NATEVTKVCPGAQCNFAFY
G-GKTVYYQYITTFQMFNLFVFLWLVNFIIA-----------LGECALAGAFATYYWTLK
KPDDIPPYPLFTSFGRAIRYHTGSLAFGSLILAAVQFFKVTLEYLDNRLKXXXXXXXXX-
----XXX------XXXXXXXXXX--------------------------------XXXXX
FDRNAYVMIAVYGKNFCRSARDAF-NLLMRNVV-KVAV---IDQLTDFVLIMGKILVSAI
IGVLAFLLFTKKIPVILEGPTTLNYYWVPLMXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
EDLERNDGSTEKPYFIAPTLHGILSKKQLIPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------MGVNYKKEL-HDSISPH------------KIWKP---KKIIWDICVCVCVCI
YIYICICVYIYFLSFLVPAAWVHGDPRRVAYPTDSKGHFCGQKGTPNENKTILFYFNLFS
CTSPSVVINLQCPTT-QICVSKCPEKFLTYMEIQFTYRTNKNYWTYYSQFCKSTFVKPAK
TLTQVLLDDDCPIAIFPSKPFLQRCFPDFSTKNGTLTVGNKTTFEDGSGKTRNAIELRAA
A-NRVNKILDARTIGMKIFEDYATTWYWILLGLIIAMLLSWMFVILLRYIAGLLFWVFMV
GVIGIIGY-GIGHCYQEYCNLQ-----GQPNSHLTVYDIGIQTDISMYFQLKQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

V
ILCLLEVFIILMLIFLRERIRISIALLKEGSKAIGYIPTTLVYPLLTFIFLSICISYWAV
IA-VYLATSGVPVYKVITPEGQCKHENTTC-DPE---IF--NTTEIAKACPGAQCNF---
---------------------------------------------CALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILASIQIFRIVLEYLDRHLKEAQNNISKF-
----LQC------CLKCCFWCLE--------------------------------TVVKF
LNRNAYIMIAIYGKNFCKSAREAF-NLLMRNVE-FAKD----------NLYIIDMFCLSN
VGVLAFLLFTQRLPTIIEGPTSLNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTIFICFC
EDLERNDGSTEKPYFLAPTLHGTLNKMQLVSQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MAWVHGDPRRVAYPTDSNGHFCGQKGTPNENKTILFYFNLFS
CTSPSLLVNLQCPTT-QICVSKCPEKFLTYMEMYFMYRTRENYWSYYSQFCKAASAKPVK
AFTQLLLDDDCPTAIFPSRPFLQRCFPDFSTKNGLLTIGNKTTFNDGSGKTRNVVELRAA
A-NGVNKILDARAIGMKVFEDYATTWYWILIGLTIAMLLSWMFVILLRVTAGFLFWVFIL
GVIGILAY-GIWHCYQEYSKLQ-----GKPNSHLSIYNIGIQTDISMYFQLKQTWFT

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILAILEVIVIVMLIFLRDRIRVSIALLKEGSKAIGYIPSTLIYPVLTFIFLSICISYWAV
TA-VYLATSGTPIYKVIAPEGQCEHENKTC-DPE---IF--NTTEIAKACPGAHCNFAFY
G-GKSLYHQYITTFQIVNLFIFLWLINFVIA-----------LGQCTLAGAFASYYWALK
KPDDIPPHPLFTAFGRAIRYHTGSLAFGSLILATIQMVRLVLQYLDNRLKDAQSNISRF-
----LQC------CLKCCFWCLE--------------------------------HVVKF
LNRHAYVMIAIYGQNFCRSARDAF-NLLMRNVL-KVAV---MDRVTEFVLTLGKILVAGC
IGILAFLLFTERIPMIVEGPTSLNYYWVPLLTVIIGSYLIAHGFFSVYAMCIDTIFICFC
EDLERNDGSAEKPYFIAPTLHGILNKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
------------------MVFGKRAASPTGKLEYGDPRTYNADFKGPVVNRSCTDVVCCM
IFL----VFIMGYILIGLVAWAHGDARRVTYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVMINLQCPTT-QICVSKCPEKFLTYVEMQILYQKDRSYWEYYRQFCKSS-AKPIK
SLPNLIMGDDCPTVVFPSKPFFQRCLPDFTNKNGTLTVGGRVQFEDGSGGMTNVLELREA
V-NGINKILDARDIALKVFEDFATTWYWIIIGLTIAMILSWTFLILLRFVAGCLFWFFMF
GVLQIVGF-GIFYCYQQYNKLQ-----KNPESSLSLYDVLIQTNINTYFQLKQTWFILL

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSVVELIIILLLIFLRKRIRLAIALLKEGSKAIGYIPSTLVYPVLTFILLSICFSYWIV
TA-VSLATSGAPVYKVSAPEGPCVHENETC-DPS---IF--SSTDVPKACPGALCNFAFY
G-GKSLYHQYLAILHLYNLFVFLWLINFVLA-----------LGQCTLAGAFASYYWAMK
KPDDIPALPLFTAFGQAVRYHTGSLAFGSLILVLIQMFKVILEYLDRHLKKTQNVVSKF-
----LKC------CLGCCFWCLE--------------------------------KLIKF
LNKNAYIMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---TDEVTHFVLILGKILISAL
IGILAFLLFTEKMPMVLGGPTSLNYYWVPLLTVILGSYLVAHGCFSVYATCVETIFLCFL
EDLERNEGSAARPFFVSPSLMKILVEQDS---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------ILRSILYFAAWVHGDPRKVIYPTDSYGQFCGQGDTPNKNKTILFYFNILK
CASPVVIINLQCPTT-QLCVSKCPDRFATYSDVQASYRYRPDQWNYFRQFCRPGFNNPRK
SAAQVLRDEDCPSMIVPSRPFLKRCFPDFSTKNGVLTVANQTTFKDGRGKTRNVTDLREA
A-NGINIVLDARSVGMKIFEDYAISWYWILIGLFIAMLLSLLFLVLLRFTAGVLFWIFIF
GVIGIIGYEGIWHCYWEYDHLK-----GIPGSDLTVYDIGFQTDFKVYLQLRQTWLA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILCGVEVIIILMLIFLRNRIRIAIALLEEGSRAIGYIMSTLFYPIVTFLLIAICISYWAV
TA-VFLATSGEPIYKIMANQTLCKYANLTC-DPE---TF--NTTNVTKLCPGAQCTFAFY
G-GESLYHKYIFIFQLANAFVFLWLVNFAIA-----------LGQCTLAGAFASYYWAYR
KPADIPLWPLFSSFGRAIRYHTGSLAFGALIIAIVQLIRVILEYLDHKLKGTQNSFTRF-
----LLG------CLKCCFWLLE--------------------------------KFLKF
VNRNAYIMIAIYGKNFCTSAKDAF-YLLMRNVV-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTHRIPVFSQEVPMLNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTLFLCFC
EDLERNDGSTAKPYFMSASLHRILGKKKLSPKKSVES-------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKPPSSQGDPRRYDPDFQGPTAKRTCTDVICCL
IFL----LFILGYVLLGLLAWAHGDPRKMAYPTDSQGHFCGQKGTPNENKTVLFYFNIFR
CTGPSMMLQLQCSTT-QICVSRCPERFLTYLDMQFLNKEDKNYWEYYRQFCKAK-AKPVE
TLRDLLISGDCPVAVYPSRPFLQRCIPDLSAINGTWTLGSRMKFEDGSGQTRTMVELREA
A-KGISDVINARTIGLKLLEDYSTSWKWILIGLTVAMALSWTFLILLRFTAGFLFWFFIF
GVLGIIGY-GIWYCFLEYSSIQ-----QRPQSTFWMYGFGIQRRVNMFFHLKETWFSMML

PF04515 // ENSGT00550000074521_4_Domain_0 (481, 904)

ILSAIEIIIIIVLIFLRTRIRVAIILLQEGSKAISYLPSALIYPVLTFVLLSICISYWAV
TA-VFLATSGVPIFKVMVPAGQCMYEDETC-DPE---IF--PYTNIPKDCPGASCNFAFY
G-GRSMYHNYILTFQVYNLFAFLWLINFVIA-----------LGQCALAGAFASYYWAMK
KPEDIPPYPLFSAFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRLKKAQNSAAQF-
----LHC------CLQCCFWCLE--------------------------------KMVKF
LNRNAYIMIALYGKNFCESTRDAF-YLLMRNIL-KVTV---TDEVTYFVLLLGKILVSGI
VGVLAFLLFTERLQIIVEGPTTLNYYWVPFLTLVFGSYMIAHGFFSVYSMCVETIFICFL
EDLERNEGSPSRPYFVTPALMNILLEQGKIKKQ-----------------

------------------------------------------------------------
------------------------------------------------------------
--------------------MA--RKGEASAPPYGEPRKFDPKFRGPIHNRHCTDVICCV
IFI----VVILGYIALGIVAWVHGDPRKVIYPTDSYGQFCGQKDTFNENKTILFYFNILK
CASPVVLINLQCPTT-QLCVSKCPDRFATYIDVQASYRYRPDQWNYFKQYCKPGFNNPRK
SVAQVLRDEDCPSMIIPSRPFLKRCFPDFSTKNGVLTVANQTTFKDGRGKTRNVTDLREA
A-NGINNVLDARSVGMKIFEDYAISWYWILIGLFIAMIVSLLFLVLLRFTAGVLFWIFIF
GVIGIIGY-GTWHCYWEYDHLK-----GIPGSDLTVYDIGFQTDFRVYLQLRQTWLAFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCVVEIIIILMLIFLRNRIRIAIALLKEGSRAIGYIMSTLFYPIVTFILIAICISYWAV
TA-VFLATSGEPVYKVMANQTLCKYANLTC-DPE---TF--NTTNVTKLCPGAQCTFAFY
G-GESLYHKYIFIFQLANAFVFLWLVNFAIA-----------LGQCTLAGAFASYYWASR
KPADIPLWPLFSSFGRAIRYHTGSLAFGALILAIVQLIRVVLEYLDHKLKGTQNSFTRF-
----LLC------CLKCCFWCLE--------------------------------KFLKF
INRNAYIMIAIYGKNFCTSAKEAF-FLLMRNVV-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTQRIPVFAQEAPALNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTLFLCFC
EDLERNDGSTAKPYFMSASLHRILGKKELSPKKAIG--------------

------------------------------------------------------------
------------------------------------MNFSLFIFYVYLF-----------
-------AISLAY---------MLRKF--FILNAGTPRAHDPHFRGPVVNRSCTDVLCCM
IFM----LFIMAYILLGLAAWVNGDPRRVAYPTDSQGYFCGQKGTPNENKSILFYFNMLT
CTSPSVVVNLQCPTT-QICVSKCPERFLTFMEIQFKYKNDSEYWTYYSQFCRTTFLKPVE
TLSQVLLDNDCPSAIYPSKPFLQRCFPDFSTKNGTLTVGNKTVFDDGSGKTRNAAELRKA
A-NGINKALDARAIGVKVFEDYATTWYWILIGLTIAMFLSWMFVMLLRFTAGLLFWIFTF
GVIGIIAY-GIWRCYLEYSRLE-----EQPGSHLNAYTIGIQTDISMYFRLKQTWFA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

LMI
ILCLLELFIILMLIFLRTRIRISIALLKEGSKAIGYIPSTLIYPALTFFFLSVCISYWAV
VA-LYLATSGAPIYKVIAPQGQCEHENKTC-DPV---GF--NTTEIAKACPGAQCHFAFY
G-GKSLYHQYITTFQLLNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAIIQMFRLILEYLDKRLQKAQSNISKF-
----LKC------CLRCCFWCLE--------------------------------KAVKF
LNRNAYVMMAIYGKNFCKSARDAF-NLLMRNIL-KIAV---MDRVTDFVLILGKILVAGC
IGVLAFLLFTERLPVIIEGPTSLNYYWVPLLTVIVGSYIIAHGFFSVYAMCIETIFICFL
EDLERNDGSAEKPYYMSQSLMKIMNRRNVETKKQ----------------

------------------------------------------------------------
------------------------------------------------------------
----------MARKRELPSIKEEPPDSPLKEDSFGKARTFDPDFKGPVSKRTCTDVLCCL
IFI----LFIIGYILLGLAAWVHGDPRKLAFPTDSEGHFCGQKNTPNENKSILFYFNFLK
CANPSVMINLQCPTR-QVCVSHCPEKFSTYTEMQINTKKNKTSWEYYKQFCKNGFDKPGK
SLKEILLTEDCPTAIYPSRPFLQRCFPDFSTRNGTLTIGNRTNFDDGRGKNRSVIELRTA
V-NGVSKIIEAKSLGMKVFEDYSTSWYWILIALVIAMVLSWIFLILLRYTAGLLFWIFIL
GVLGVIGY-GIWYCYSEYNNLQ-----KESSSDLTIYDVGIQSDFTIYFQLKQTWFA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILCIIEMLVIVMLIFLRNRIRISIALLKEGSKAIGYIPSTLFYPLLTFTFLSICISYWAV
TA-VFLATSGVPVYKVITPGVQCVHDNKTC-DPE---IF--NTTDIPKACPGSMCSFAFY
G-GNSLYHQYIPTFQIYNLFVFLWLINFVIA-----------LGQCALAGAFAAYYWAMQ
KPDDVPPLPLFTAFGRAIRYHTGTLAFGSLILALVQMFRIVLEYVDRHLKDAKGSLAKF-
----IQF------CLQCCFWCLE--------------------------------KLLKF
LNRNAYIMVAIYGKNFCKSARDAF-NLLMRNVI-KVAV---MDRVTDFVLFLGKILVAGS
IGILAFLFFTQKVPMIVKGPTTLNYYWVPLLTVIAGSYIVAHGFFSVYAMCVDTLFICFL
EDIERNDGSTERPYYMNQTLLKILNKQNVQTKER----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------NRNKSILFYFNLLK
CTSPSVMINLQCPTT-QICVSKCPERFVTYVEMQISTKHNRSHWAYYRQFCKPSFVMPKK
SLTEILLDEDCPTAIFPSKPFLQRCFPAFSTDNGTLTVGNKTTFEDGSGKTRNVMELRAA
A-NGVNRLLKGRSIGTKVFEDYSTSWFWILTGLIIAMVLSWMFLILLRYIAGLLFWIFML
GVLGIIGY-GIWHCYREYQKLQ-----ASSTSELTIYDIGIQTDLSIYFELKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

TFMI
ILCIVEAIITIMLIFLRNRIRLAIALLKEGSKAIGYIPSTLIYPVLTFILISICISYWAV
TA-VFLATSGTPIYKVITPGGQCVHENKTC-DPEVMQIF--NTTEIYKACPGAMCNFAFY
G-GKSLYHQYITIFQLYNLFAFLWLINFVLA-----------LGQCTLAGAFAAYYWATK
KPDDIPPFPLFTAFGRAIRYHTGSLAFGSLILALIQMFRITLEYMDHRLKNAHNKVSKF-
----LQC------CLKCCFWCLE--------------------------------KVVKF
LNRNAYIMIAIYGKNFCKSARDAF-NLLMRNVIHRVAV---MDKVTEFVLMLGKILVAGS
IGILAFLLFTQRIPMILKGPTSLNYYWVPMLTVIFGSFLIAHGFFSVYAMCVDTIFICFC
EDLERNDGSTEKPYFISPSLHGILIKKQLVPREQ----------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------CL
QQL----LLIEFLSFLIPAAWVYGDPRRMAYPTDSQGHFCGQKGTPNENKSILFYFNILS
CTNPSVMITLQCPTT-QICVSKCPDKFLTYVKMQILYKRDKRFWEDYSPFCKAG-AKPVK
SLPQVILDDDCPAAVYPSKPFLQRCLPDFSFTNGSLTIGDHVLFEDGNGRMRNVTELKDA
V-KQINEILNARKLGLKVFQDYSLTWYWILTGLVIAMFLSWIIVILMRYIVGLLFWIFAI
GVLGIIGY-GIWHCYNEYDTLR-----KNPNAPQTLYDIGIQTDITLYFRLKQIWFA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
MLSILEAIVVILMIFLRKRIRVAIFLLQEGSKAIRYIPSTLFYPLLTFTLLSICISYWVV
TA-VFLATSGIPVYKVIDPEGHCEHENETC-NPE---IF--KTSAIAKACPGALCNFVSY
G-GQTLYEQYIPTFHAYNLFVLLWLINFVIA-----------LGQCSLAGAFATYYWAMN
KPKDIPPHPLFTAFGRAIRYHTGSLAFGSLILATIQIFKMFLEYLDRRLKHVHNKFLKL-
----LQH------CLKCCFWCLD--------------------------------KVIKF
LNRNAYIMIAVYGKNFCRSTRDAF-NLLMRNIL-KVAV---TDEVTFFVLFLGKILVAGS
IGVLGFLFFTQRMAMIVEAPRSLNYYWVPLLTVVLGSYLIAHGFFSVYAMCVETIFLCFC
EDLERNDGSTEKPYFVAPKLHEILIKKELVPQKQKR--------------

------------------------------------------------------------
------------------------------------------------------------
--------MSD---------EGELPATYLEGKNCSDPRIHDPHF-GPVVNKSCTDVLCCM
IFI----LFIIAYILLGLVAWVNGDPRRVAYPTDSQGHFCGQKGTPNENKPILFYFNLLS
CTSPSVVVNLQCPTR-QICVSKCPEKFLTYMEIQFMYRKDRNDWTYYSQFCKSAFLKPAK
TLTQVLLDDDCPTAIFPSKPYLQRCFPDFSTKNGTLTVGNKTVFEDGSGKTRNAVELRAA
A-NGINKVLDARAIGVKVFEDYATTWYWILIGLTIAMLLSWMFVILLRFTAGFLFWLFTF
GVIGIIAY-GIWHCYREYSNLQ-----GQPNAHLTVFHIGIQTDISMYFQLKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMI
ILCILEVFIILMLIFLRDRIRISIALLKEGSKAIGYIPTTLIYPVLTFILLSICISYWAV
IA-VYLATSGVPIYKVIAPEGQCKHENKTC-NPE---IF--NTTEIAKACPGAQCRFAFY
G-GATLYHQYITTFQIFNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAVVQMFRLILEYLDKRLKQAQNNISKF-
----LKC------CLRCCFWCLE--------------------------------KAVKF
LNRNAYVMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---MDRVTDFVLILGKILVAGC
IGVLAFLLFTERLPMIIVGPTSLNYYWVPLLTVMIGSYLIAHGFFSVYAMCIETIFICFC
EDLERNDGSTEKPYFITPTLHGILNKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------YARKKKQSEPRTYDPDFQGPTANRRCTDVLCCI
IFI----VFIIGYIVLGLVAWVHGDPRRVAYPTDSQGHFCGQKGTPNEKKPILFYFNLFR
CASPAIMVNLQCPTT-QVCVSKCPEKFLTYLEMQLLSKTDKSYWEYYRQFCKPT-AQPAK
SLTEVLLNGDCPTAVFPSRPFLHRCFPDFSTRNGTLTVGSRILFEDGSGKTRNAVELREA
A-NGINKILDARTVAMKVFEDYATTWYWILIGLTISMILSWVFLMLLRYTAGFLFWFFML
GVLGILGY-GIWYCYREYNKLE-----DNPNSSLSVYDIGIQTNISIYFQLKQTWFSIM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSILEGTIILLLIFFRKRIHVAIILLKEGSKAIGYIPTTLIYPIVTFILLAICISYWAV
TA-IFLATSGVPVYKVVVPEGKCVHENETC-DPE---MF--NTTEVIKSCPGALCNFAFY
G-GMSLYHKYIPTFHIYNLFLFLWLINFVIS-----------LGQCALAGAFATYYWAMR
KPDDIPPHPLFTAFGRAIRYHTGSLAYGSLILAVIQTFKATLEYLDRRIKDAQNIFAKF-
----LQC------CLKCCFWCLE--------------------------------NMVKF
LNRNAYIMQQLYFKHKTT--LSFF-S----LIL-RVAV---TDEVTHFVLLLGKILVSGF
IGLLAFLLFTERLPMVDYEPTSLNYYWIPLLTVIVGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSAEKPYFITPNLHGILTKKQPVPQKQKVSRK-----------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------CCV
IFL----VFIMGYILLGLMGEI----REM---------------YYLLNKTTLFYFNMLR
CTSPSVVINLQCPTT-QICVAKCPEKFLTYVEMQILYKTDSRYWEYYRQFCKPT-AKPVS
SVPALLLNEDCPSMIFPSKPFLQRCFPDFIKENGTLTIGHRMHFEDGRGRMRTVLELREA
A-NGINKILNAREIAFKVFEDYATSCENIFLC-------------LLRPRSDFIFVD---
-SFLKFVF-SMPFCFSDRLKIGQRYLETHPSILITLSAPETNGH----------------
--------------------------VLFYF

PF04515 // ENSGT00550000074521_4_Domain_0 (512, 904)

RAIGYIPSTLVYPAFTFILLLICFSYWVV
TA-VSLATSGVPVYKVSAPEGPCIHENETC-NPT---NF--NATNVPKECPGALCNFAFY
G-GKSLYHQYISTLHWYNIFVFLWLVNFVFA-----------LGQCTXXXXXXXXXXXXK
KPDDIPSLPLFTSFGQAIRYHTGSLAFGSLIIAVVHLFKMILEYLDXHLKNAQSHTSKF-
----LKY------CLTCCFWCLE--------------------------------KMVKF
LNRNAYIMIAIHGKNFCMSARDAF-NLLMRNIL-KVAV---TDEVTHFVLLLGKLLVTSF
IGLLAFLLFTEKTPAILGGPTSLNYYWVPLLTVILGSYLVAHGCFSVYTTCIETIFLCFC
EDLEGNDGSPEKPYFITPSLHEVLVKKQPVLQKQKK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MVPEGKCRYEDEIC-DPE---IF--PKTNIPKLCPGASCNFAFY
G-GRS

PF04515 // ENSGT00550000074521_4_Domain_0 (606, 904)

VYHSYIMTFQIYNLFAFLWLINFVLA-----------LGQCTLAGAFASYYWAMR
KPEDIPKYPLFISFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRLKKKENRVSRF-
----LQ------GCLRCCFWCLE--------------------------------KLVKF
LNRNAYIMISLYGKNFCDSTKDAF-YLLMRNIL-KVAV---TDEVTHFVLLLGKILVSGI
VGVLAFLLFTERLQRIIEGPTTLNYYWVPLLTVVIGSYLVAHGFFSVYSMCVETIFICFC
EDLERNDGSAEKPYFVTPSLHRILTKKHPVSQRQTE--------------

------------------------------------------------------------
------------------------------------------------------------
--------MS---------DKEEQPDTSLDVETYGNPRTFDPNFKGPIAKRNCTDVLCCI
IFV----LFIIAYILLGLVAWVHGDPRRVAYPTDSKGHFCGQKGTPNENKTILFYFNLFS
CTSPSVVVNLQCPTT-QICVSKCPEKFLTYMEIQFSYRKNKHYWTYYSQFCKSPFVKPVK
TLSQVLLDDDCPTAIFPSKPFLQRCFPDFTTKNGTLTVGNKTTFEDGSGKTRNAIELRTA
A-NRVNKILDARAIGMKVFEDYASTWYWILIGLTIAMLLSWMFVILLRFIAGFLFWVFMA
GVIGIIGY-GIWYCYQEYSNLQ-----GRPNSHLSIYDIGIQTDISMYFQLKQTWFA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILCLLEVFIILMLIFLRGRICISIALLKEGSKAIGYLPTTLIYPVLTFIFLFICIAYWAV
TA-IYLATSGVPIYKVISPERTCEHENTTC-DPE---IF--NTTEIAKACPGAQCNFAFY
G-GKSLYHQYVPTFQIFNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILALVQMFKFILEYLDRRLKEAQNNVCKF-
----LQC------CLKCCFWCLE--------------------------------RMVKF
FNRNAYVMIAIYGKNFCRSARDAF-NLLMRNVL-KVAV---MDKVTDFVLILGKILVAGC
IGVLAFLLFTHRLPTMIEGPTSLNYYWVPLLTVIIGSYLVAHGFFSVYAMCIDTIFICFL
EDIERNDGSPERPYYTSQSLLKILNEPNMQTKKH----------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIILGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-ATPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVVELGIA
A-NGINKLLDAKSLGLKVFEDYARTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----ERPSSVLTIYDIGIQTNISMYFELQQTWFAFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPGGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIITLIQMFKIVLEYLNHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKLLVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFVTPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
----------------------------------------------------MS------
--GTEE-----------------PADTPSEEEDFGDPRTYDPDFKGPVGNRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVMLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPAK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSRMVFQDGNERQRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMFLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWYCYQEYTKLQ-----EHPSSVLTIYDIGIQTSISMYFQLQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVTVILMLIFLRNRIRVAIILLKEGSKAIGYIPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEMAKACPGALCSFAFY
G-GKSLYHQYIPTFHVYNLFIFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTSFGRAIRYHTGSLAFGSLIIALIQMFKIILEYLDHRLKRTQNKLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAV---TDEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPTSLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
----------------------------------------------------MT------
--DEEESP--EN--PSEKMVFEKRAASPSRKPEFGDPRMYDPDFKGPVVNRSCTDVVCCM
IFI----VFIMGYILLGLVAWANGDARRVTYPTDSQGHFCGQKGTPNENKTVLFYFNLLR
CASPSVMINLQCPTT-QICVSKCPEKFLTYMEMQILYKKDSSYWEYYRQFCKST-AKPAK
SLPEVLVDDDCPTAVFPSKPFLQRCFPDFINRNGTLTVGDRVLFEDGSGRMRTALELREA
A-NGINKILDAREIALKVFEDYATTWYWIIVGLTIAMILSWTFLILLRFIAGCLFWFFTL
GMLEVVGY-GIVYCFQQYTKLQ-----QHPESSLTIYNIGIQNNISMYFQWKQTWFILM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCVLELTIILLLIFLRKRIHLAIVLLKEGSKAIGYIPSTLVYPVLTFILLSVCFSYWIV
TA-LFLATSGVPVYKVSAPEGQCIHENETC-DPR---IF--NMTDVPKACPGALCNFAFY
G-GKSLYHQYISTLHLYNLFVFLWLINFVVA-----------LGQCTLAGAFASYYWAMK
KPDDIPALPLFTAFGQAVRYHTGSLAFGSLILALIQMFKVILEYLDRRLKNAQNNISKF-
----LKC------CLGCCFWCLE--------------------------------KMVKF
LNKNAYIMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---TDEVTNFVLLLGKILVSGF
IGILAFLLFTEKMPVIFGGPISLNYYWVPLLTVIFGSYLVAHGCFSVYATCVETIFLCFC
EDLERNDGSAEKPYFITPSLHEILVKKQPVPQKEKE--------------

------------------------------------------------------------
------------------------------------------------------------
-----E-----------------PSDTSLEEGDFGEPRTYDSDFKGPVANRSCTDVLCCM
VFL----LFIAGYILLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNMLR
CTSPSVMSTLQCPTT-QICVSKCPEKFLTYMEMQLLYTKDKSYWEDYRQFCKTT-AQPAK
SLPQLLLDDDCPAAIFPSRPFLQRCFPDFSTNNGTLTIGSKVLFQDGNGKTRSVVELRDA
A-NGINKILDARTLGLKVFEDYATTWYWILIALTTAMLLSWMFLILLRLIAGCLFWVFMS
GVLGIIGY-GIWHCYQQYTDLQ-----ERPSSVLSIYDIGIQTNISMYFELKQTWFALM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIVEVTVILMLIFLRNQISVAIIL------AIGYIPSTLIYPLLTFILLSICICYWAV
TA-VFLATSGVPVYKVVTPAGNCVHENQTC-DPE---LF--NSTEIAKVCPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVVA-----------LGQCALAGAFATYYWAMK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLTIALIQTFKMILEYLDHRVKHGENILAKF-
----LQC------CLRCCFWCLE--------------------------------KVVKF
LNKNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAV---TDEVTYFVLFLGKVLVTGS
IGVLAFLFFTERMPTIAAGPTSLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSAEKPYFISPNLHRILVKKQLGPQKQKE--------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLIIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVVA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------AWVHGDPRRVAYPTDSKGHFCGQKGTPNENKTILFYFNLFS
CTSPSVVVNLQCPTT-QICVSKCPEKFLTYMEIQFAYRTNTHYWTYYSQFCKSPFVKPAK
TLTQVLLDDDCPTAIFPSKPFLQRCFPDFTTKNGTLTVGNKTTFEDGNGKTRNAIELRTA
A-NRVNKILDARAIGMKVFEDYATTWYWILIGLTIAMLLSWMFVILLRFIAGFLFWVFMV
GVIGIIGY-GIWHCYQEHSNLQ-----GRPNSHLTIYDIGIQTDISLYFQLKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMI
ILCLLEAFIILMLIFLRERIRISVALLKEGSKAIGYLPTTLIYPVLTFIFLSICIAYWAV
TA-IYLATSGVPVYKVISPEGKCKHENTTC-DPE---IF--NTTEIAKACPGAQCNFAFY
G-GKSLYHQYVPTFQMFNLFVFLWLVNFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILALVQMFKFILEYLDRRLKEAQNNISKF-
----LQC------CLKCCFWCME--------------------------------KMVKF
FNRNAYVMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---MDKVTDFVLILGKILVAGC
IGVLAFLLFTHRLPTMIEGPTSLNYYWIPLLTVIIGSYLVAHGFFSVYAMCIDTIFICFL
EDVERNDGSAERPYYMSQSLLKILNEPSMQTKKH----------------

------------------------------------------------------------
----------------------------------------------------MN------
--DEEE-----------------LQGSTYEKEDFGHARPHDPDFKGPVANRSCTDVLCCM
IFL----LFIIGYILLGLVAWVHGDPRRVAYPTDSQGHFCGQKGTPNENKTILFYFNLLS
CASPSVMVNLQCPTT-QICVSKCPEKFLTYMEMQFLYKKDKSYWEDYRQFCKTS-AKPVK
SLPQLLLDDDCPTAVFPSKPFLQRCFPDFSTRNGNLTIRSRMLFQDGNGRTRSVIELREA
A-NRINKIFEARALGMKVFEDYATTWYWILIGLTIAMVLSWMFLILMRFIAGFLFWIFVF
GVLGIIGY-GIWHCYQEYCNLQ-----DHPNATLSIYDIGIQTNISMYFQLKQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 710)

I
ILSIIEASVILMLIFLRNRIRVAIFLLKEGSKAIGHIPSTLIYPFLTFILLSICISYWVV
TA-IFLATSGVPVYKVIAPEGQCIHENETC-DPE---IF--NTSEIAKACPGALCTFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPPHPLFTAFGRAIRYHTGSLAFGSLILASIQMFKMILQYVDQRL

ENSGT00550000074521_4_Linker_0_4 (710, 789)

K----------
------------------------------------------------------------
--------

PF04515 // ENSGT00550000074521_4_Domain_4 (789, 904)

IAIYGRNFCRSARDAF-NLLMRNIL-KVAV---TDEVTYFVLFLGKILVSGS
MGILAFLFFTQRMPMIAAGPTSLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFLCFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPKKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------------------MD--RDEENYYGKHGEPRKFDPKFRGPIHNRRCTDIICCV
IFI----VVILGYIALGVVAWVHGDPRKVIYPTDSYGQFCGQRDTLNENKTILFYFNILK
CASPVVLINLQCPTT-QLCVSKCPDRFATYIDVQASYRYRPDQWNYFRQFCKPGFNNPRK
SVAQVLRDEDCPSMIIPSRPFLKRCFPDFSTKNGVLTVANQTTFKDGRGKTRNVTDLREA
A-NGINNVLDARSVGMKIFEDYAISWYWILIGLFIAMLLSLLFLVLLRFTAGVLFWIFIF
GVIGIIGY-GIWHCYWEYDHLK-----GIPGSDLTVYDIGFQTDFKVYLQLRQTWLA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILCGVEVIIILMLIFLRNRIRIAIALLKEGSRAIGYIMSTLFYPIVTFLLIAICISYWAV
TA-VFLATSGEPVYKVMANQTLCKYANLTC-DPE---TF--NTTNVTKLCPGAQCTFAFY
G-GESLYHKYIFIFQLANAFVFLWLVNFAIA-----------LGQCTLAGAFASYYWAYR
KPADIPLWPLFSSFGRAIRYHTGSLAFGALILAIVQLIRVILEYLDHKLKGTQNSFTRF-
----LLC------CLKCCFWCLE--------------------------------KFLKF
INRNAYIMIAIYGKNFCTSAKEAF-FLLMRNVV-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTQRIPVFAQEVPMLNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTLFLCFC
EDLERNDGSTAKPYFMSASLHRILGKKKLSPKKA----------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTASEEEDFGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLMIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLNHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEKDFGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SVTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMVLSWTFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYINLQ-----EHPSSVLTIYDIGIQTNISMYFELQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFIVA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPTSLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------MC----------
---------------------------------IEPQSHQPLQIYIYIFCLLCF------
--FLEK-----------------PADTASEEEDFGDPRTYDPDFTGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNPLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLMIAMVLSWIFLILLRFIAGCLFWVFVI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLNHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

MAGERRAERLGGSPSSAPPPCLPPARGKGRPGSQRPQLLLLARRSEAGVCVYLPQASLSR
SFPASRAAWSSGEERGALLLASASAAGAGGGGGSGGGGKGKQAWWPLLSPPPRPRCPRCR
QTRAERRPGPAGRAGAAKPRGTMARKGDPAASPYGEPRKFDPKFSGPIHNRHCTDILCCV
IFV----VVILGYIALGIVAWVHGDPRKVAYPTDSYGQFCGQKDTPNENKTILFYFNILK
CASPIVLINLQCPTT-QLCVSKCPDRFATYIEMQSSYR---NYWEYFRQFCKPGFNKPRK
SVTQVMRDEDCPSMIVPSRPFLQRCFPDFSTKNGVLTVANQTTFRDGRGKTRNVTDLREA
A-NGINNVLDARSVGMKIFEDYASSWYWILIGLFIAMVVSLLFLVLLRFIAGILFWIFIF
GVIGVIGY-GIWHCYWEYHHLH-----GIPGSDLTIYDIGFQTDFRVYLQLRQTWLA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 907)

FMI
LLCIVEVVIILMLIFLRNRIRIAIALLKEGSRAIGYIMSTLFYPIITFILIAICISYWAV
TA-VFLATSGEPVYKVMANQSLCKYANLTC-YPE---TF--NTTNVTKLCPGAQCTFAFY
G-GESLYHRYILVFQIFNVFVFLWLVNFAIA-----------LGQCTLAGAFASYYWAFR
KPSDIPTCPLFASFGRAIRYHTGSLAFGSLILAIVQLIRVILEYLDHKLKGSQNAFAKF-
----LLC------CLKCCFWCLE--------------------------------KFLKF
INRNAYIMIAIYGKNFCASAREAF-FLLMRNVV-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTHRIPIFTHEAPSLNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTLFLCFL
EDLESHDGSPARPYYMSKSLLKILNKKNMQTKKQ----------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------SCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----AHPSSVLTIYDIGIQTNISMYFELQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVVA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RGCTDVLCCM
VFI----LFITGYIILGLIAWVHGDPRRVAYPTDSKGHFCGQKGTPNENKSILFYFNLLS
CTSPSVMINLQCPTT-QICVSKCPEKFLTYLEMQLPFKRDKHSWEYYSQFCKSPIFHSAK
SLSEIVMDDECPAAIFPSKPFLRRCFPDFSTKNGTLTVGNKTTFEDGKGQIRNAVELRAA
A-KNINKVLDAKAFGVKVFEDYATSWYWILIGLTIAMLLSWLFLLLLRFIAGFLFWIFVL
GVLGIIGY-GIWHCYQQYRNLQ-----ERPNSHLTIYDLGIQTDISMYLQLKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMV
ILSILEVLVILLLIFLRDRIRISIALLKEGSKAIGYVPTTLIYPVFTFFLLSICICYWAV
IA-VYLATSGTPIYKVITPEGKCKYENRTC-DPD---IF--NTTEMSRACPGAQCNFAFY
G-GNSLYYQYISTFQIFNLFIFLWLINFVIA-----------LGQCALAGAFASYYWALR
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLLLALIQMFRIALEYLDKRIKDNQNNIAKF-
----LQH------CLKCCFWCLE--------------------------------KVVKF
LNRNAYVMIAIYGKNFCRSAKDAF-DLLIRNIL-KVAV---LDKVTDFVLVLGKILVSGC
IGVLAFLLFTQRISIIIEGPTSLNYYWVPLLTVIAGSYLVAHGFFSVYAMCIDTIFICFC
EDLERNDGSTEKPYFIAPALHGILNKRHLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------------------MSDSESTEFEDQDLGDPRRYDPDFQGPTTKRSSTDVMCCM
IFV----LFIMGYILLGLLAWVHGDPRKMAYPTDSQGQFCGQKGTPNENKTVLFYFNIFR
CTGTSMMLRLQCSTT-QICVSRCPERFLTYVDMQILNKEDKNYWEYYRQFCKAQ-ARPVE
TLADLLSSGDCPLAVYPSRPFLQRCVPDFSAINGNLTLGSRMHFEDGGGQKRTVVELREA
A-SGISDVIDARAIGLKVLEDYSTSWKWILIGLTIAMALSWTFLVLLRFTAGFLFWFFIF
GVLGIIGY-GIWYCFLEYNSIQ-----QKPQSAIWMYGIGIQTRLNMFFHLKETWFSMM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 900)

I
ILSAIEVVIIIVLIFLRTRIQVAIILLKEGSKAIGYLPSALVYPFLTFILLSICISYWAV
TA-VFLATSGVPIFKVMVPEGECIHEDEAC-DPE---IF--PNTDIPKACPGASCNFAFY
G-GRSMYHNYIATFQLYNLFAFLWLINFVIA-----------LGQCALAGAFASYYWAMR
KPEDIPRYPLFTAFGRAVRYHTGSLAFGSLILAFVQMFKVIVEYLDRRLKKAQNSAAQF-
----LHC------CLRCCFWCLE--------------------------------KMVKF
LNRNAYIMIALYGKNFCESTRDAF-YLLMRNIL-KVKV---TDEVTYFVLLLGKVLVSGI
VGVLAFLLFTERLHEIVEGPTSLNYYWVPFLTLVFGSYLIAHGFFSVYSMCVETIFICFS
VYKDADAV------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MWSTVANVHSKIRGCTDVLCCM
IFV----LFVIGYILLGFLAWTHGDPRRVAYPTDSQGHFCGQKGTPNENKTILLYFNLFR
CANPSMILRLQCPTT-QICVSKCPERFLTYLEMQFLTREDKNHWEYYRQFCKTT-ARPAK
SLSELLSRGDCPPAVYPSRPFLQRCLPDFSKINGTLVTESSVHLKDGSGKTRNIMEFREA
T-RGITKILDARNIGLKVFEDYATTWKWILIGLTVAMALSWIFLILLRFTAGFLFCVFMF
GVLGIIGY-GIFYCYLQYIDLQ-----QKPQSSILIYEPGLKATISMFFLLKYTWLSMM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILFIIEAIIIIVLIFLRRLMRVAITLLKEGSKAIGYIPSTLVYPVLTFVLLSLCISYWAV
TA-FFLATSGLPIFKVMVPQGKCIHEDETC-DPE---IF--PKSHIPKVCPGASCNFYSY
G-GKSVCHSYHLIFQIYNLFALLWLVNFVIA-----------LGQCTLAGAFASYYWAMR
KPEDIPKCPLFIAFGRAVRYHTGSLALGSLILASVQVFKVIIEYMSYRLKNLKESLPLL-
----THLASPLVSMILRALWGQGQRAPRHPTNPNAGKRTGLLVWKMAMNCAVLSVVRATN
KSTNHFLQIALYGKNFCESTKESF-SLLMRNIL-KVAV---TDEITCFILLLGKILVSGI
VGLLAFLLFTERLQKIVEGPTTLNYYWVPFLTLVLGSYLIAHGFFSVYSMCVKTIIICFC
EDLERNDGSAEKPYFVTPSLHRVLTKTRPVSQRQRE--------------

------------------------------------------------------------
------------------------------------------------------------
----------------------MAKQEENSKRKPGEPRKFDPKFRGPIHNRHCTDVLCCI
IFI----VVILGYIVLGIVAWIHGDPRKVAYPTDSYGQFCGQKETPNENKTILFYFNILK
CASPIVLINLQCPTT-QLCVSKCPDRFATYIDMQASYRYNKSYWEYYRQFCKPGFNKPWK
SVAQVLRDEDCPSMIIPSRPFLKRCFPDFSTKNGVLTVANRTTFKDGKGKTRNVTDLREA
A-NGINNVLDARSVGMKIFEDYASSWHWILIGLFIAMIVSLLFLVLLRFTAGVLFWIFIF
GVIGIIGY-GIWHCYWEYNHLW-----GKPGSDLTIYDIGFQTDFRVYLQLRQTWLG

PF04515 // ENSGT00550000074521_4_Domain_1 (478, 512)

FMI
LLCIVEVIIILMLIFLRNRIRIAIALLKEGSR----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------MNDKGYPNAYDPNFKGPVAKRSCTDVLCCI
IFI----LFIIAYILLGLVAWIHGDPRRVAYPTDSKGHFCGQKGTSNENKTILFYFNLFS
CTSPSVVVNLQCPTT-QICVSKCPEKFLTYMEIEFAHKTSQNYSTYYSQFCKTPFGKPAK
ALAQLLLDDDCPTAIFPSKPFLQRCFPDFATNNGTLTVGNKTTFEDGSGRTRNAIELRTA
A-NRVNKILDARAVGMKIFEDYATTWYWILIGLTIAMLLSCMFVILLRFIAGILFWVFMV
GVIGIIGY-GIWHCYQEYNNLQ-----GRPNSHLSVYDLGIQTDLSMYFQLKQTWLA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILCILEVFIILMLIFLRERIRISITLLKEGSKAIGCIPTTLIYPILTFIFISICIAYWAV
IA-IYLATSGVPIYKVIAPEGKCKHENTTC-NPE---IF--NTTEIAKACPEAQCNFAFY
G-GKSLYHQYVPTFQMFNLFVFFWLINFVIA-----------LGQCALAGAFASYYWAFR
KPDDIPPHPLFTAFGRAIRYHTGSLAFGSLLLALIQMFKIVLEYLDRRLKDPQNNISKF-
----LQC------CLKCCFWCLE--------------------------------NVIKY
FNRNAYVMIAIYGKNFCRSARDAF-NLLMRNIL-KIAV---MDKVTDFVLILGKILVAGC
IGMLAFLLFTQRLPTIIEGPTSLNYYWVPLLTVIIGSYLVAHGFFSVYAMCIDTIFICFL
EDLERNDGSTERPYYMSQSLLKILKEPTVRTKKH----------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------EPRTYDPNFRGPIYKXXXXXXXXXX
XXX----XXXXXXXXXXXXXLAHGDAKKVAYPTDSNGEFCGQKNTHNEEKNFLFYFNTLQ
CANSVMLTRLWCPTRQXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX
PTPEVFQKEVCPLMIFPSKSXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX
XXXGINMVLNQRTIGLKVFEDFVSSWHWILTXXXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXXXXXXIWICYREYDRLQ-------SKRPSTLYDLGFQYDLRVYLQLQQTWL

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 932)

AFMI
LLSILDVFVLLAILYLRKRIQIAVTLLKEGSRAIGFIPHSLFYPILTFFLISICISYWIM
IA-VLLATSGKAVYKVLNVGANCRYANETC-DPT---TF--HSTNISKECPGADCSFAFY
G-GNQLY-DFVLIFQLFNAFVFFWLVNFSIA-----------LGQCTLAGAFASYYWAFQ
KPQDIPSHPLCASFGRALRYHTGSLAFGSLILSVVQTLRVLLEYLNYRLKGSENACSRF-
----LLC------CFRCCFWCLE--------------------------------KVLKF
LNRNAYIMIAIYGQNFCSAAREAF-KLVMRNVV-RIAV---LDKVTEFLLWMGKLLICTG
IGILGYMFFTKKLPF---TAPTLNYYWVPLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
EDLERNDGSLEKPYYMSPKLLQILGKKQAQKH------------------

------------------------------------------------------------
----------------------------------------------------MS------
--DEEE-----------------PPDSVSEEQDFGEPRPYDPGFKGPIAERNCTVILCCM
VFI----LFVLGYIFLGLAAWVHGDPRRVAYPTDSEGHFCGQKGTPYENKSILFYFNLFS
CASPSVLINLQCPTT-QICVSKCPEKFLTYLEIQTLYKRDESYWEYYRQFCKPS-AKLMK
XXXXXXXXXXXXXXXXXXXXXLQRCFPDFSTKNGTLTVGSRTLFEDGSGKTRNAIELRQA
A-NGVNKILEARSVGLKVFEDYVTTWHWILMGLIIAMILSWMFLILMRFIXXXXXXXXXX
XXXXXXXX-XIWYCYQEYTSLQ-----EQPSSSLTVYDIGIQTNMNMYFHLKQAW

PF04515 // ENSGT00550000074521_4_Domain_0 (476, 933)

FVLTI
LLSITEGSVVLLLIFLRKQIRVAIFLMKEGR-AIGCIPGTLLYPILTFILLSICISYWAV
TA-IFLATSGIPIYKVVIPQGQCIHENKTC-DPX---XX--XXXXXXXXXXXXXX-XXXX
XXXXXXYHQYISTFHVYNLFVFLWLVNFVIA-----------LGQCALSGAFATYYWTGN
KCDDIPPHPLFTSFGRALRYHTGSLAFGSLLIALIQFYRIVLQYMDRHLKNAQNTL-KF-
----FQC------CLKCCFWCLE--------------------------------NVVKF
LNKNAYIMXXXXXXXXXXXXXXXX-XXXXXXXX-XVAV---TDEVTFLILLLGKILVTGI
IGVLAFLLFTERMPIIVEGPTSLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSAEKPYFITPNLHGILFKKQLIPQKQKEQ-------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------SQHFGRPRWVDHEVRSSKPAWSCTDVLCCM
IFL----LCIIGYIILGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVVELGIA
A-NGINKLLDAKSLGLKVFEDYARTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----ERPSSVLTIYDIGIQTNISMYFELQQTWFAFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPGGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLNHRLKRTQNTFSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKLLVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFVTPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
-------------------------------------------------MIQLF------
--FTEE-----------------PPDSPFEEQDFGEPRAYDADFKGPIADRNCTDVLCCL
VFL----LFIFGYILLGLVAWIHGDPRRVAYPTDSQGHFCGQKGTPNENKTILFYFNLFS
CTSPSVMINLQCPTT-QICVSKCPEKFLTYVEMQILYKRDKSYWEYYSQFCKPT-AKPLK
TLPEILLDNDCPTAIFPGKPFLQRCFPDFSTKNGTLTVGSRTLFEDGNGKTRNVIELREA
A-NGINKILDARSVGLKVFEDYATTWHWILIGLTIAMVLSWIFLILMRFIAGFLFWFFMF
GVLGIIGY-GIWYCYQEYRNLQ-----EHPGSTLTIYDIGIQTNINMYFHLKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 908)

ILMV
LLCITEVTITLMLIFLRKQIRVAIILVKEGSRAIGCIPGTLLYPVLTFILLSICISYWAV
TA-VFLATSGIPVYRVVTPQGQCIHENKTC-DPE---TF--NTTDVPKVCPGALCNFAFY
G-GKSLYHQYISTFHVYNLFVFLWLINFVIA-----------LGQCALSGAFATYYWTVN
KPDDIPPHPLFTAFGRAIRYHTGSLAFGSLIIALIQLFRIVLQYMDRHLKNAQNGVSRF-
----LQC------CLKCCFWCLE--------------------------------NVVKF
LNKNAYIMIAVYGENFCTSARDAF-NLLMRNIV-KVAV---TDEVTFFILILGKILVCGI
IGVLAFLLFTERMPTIVEGPTSLNYYWVPLLTVIFGSYLIAHGFFSVYAMCIETIFICFL
EDLERNDGSAARPYFVAQSLMKILTEDSIHNKGR----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MVPQGKCIHEDETC-DPE---IF--PKSHIPKVCPGASCNFYSY
G-G

PF04515 // ENSGT00550000074521_4_Domain_0 (604, 904)

KSVYHSYHLIFQIYNLFALLWLVNFVIA-----------LGQCTLAGAFASYYWAMR
KPEDIPKCPLFIAFGRAVRYHTGSLALGSLILASVQVFKVIIEYMSYRLKKTQNRVSRF-
----LKC------CLRCCFWCL------------------------E--------KLVKY
LNRNAYIMIALYGKNFCESTKESF-SLLMRNIL-KVAV---TDEITCFILLLGKILVSGI
VGLLAFLLFTERLQKIVEGPTTLNYYWVPFLTLVLGSYLIAHGFFSVYSMCVKTIIICFC
EDLERNDGSAEKPYFVTPSLHRVLTKTRPVSQRQRE--------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWLFMI
GVIGIIDY-GIWHCYQQYTNLQ-----ERPSSVLTIYDIGIQTNISMYFELQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGRCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFIFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTFSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVAQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKHPSSQGDPRRYDPDFQGPTAKRTCTDVLCCL
IFL----LFILGYVLLGLLAWAHGDPRKMAYPTDSQGHFCGQKGTPNENKTVLFYFNIFR
CTSPSMMLRLQCSTT-QICVSRCPERFLTYLDMQFLSKEDKNYWEYYRQFCKAK-AKPVE
TLRDLLISGDCPLAVYPSRPFLQRCIPDLSALNGTWTPGSRMKFEDGSGQTRTMLEFREA
A-NGISDLINARTIGLKLLEDYATSWKWILIGLTVAMALSWTFLILLRFTAGFLFWFFIF
GVLGIIGY-GIWYCFLEYSSIQ-----QRPQSTFWMYGFGIQRRVNMFFHLKETWFSMM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSAIEIIIIIVLIFLRTRIQVAIILLQEGSKAISYLPSALIYPVLTFILLSICISYWAV
TA-VFLATSGVPIFKVMVPAGQCIYEDETC-DPE---IF--PYTNIPKDCPGASCNFAFY
G-GRSMYHNYILTFQVYNLFAFLWLINFVIA-----------LGQCALAGAFASYYWAMK
NPDDIPPYPLFTAFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRVKKAQNSAAQF-
----LHC------CLQCCFWCLE--------------------------------KMVKF
LNRNAYIMIALYGKNFCESTRDAF-YLLMRNIL-KVTV---TDEVTYFVLLLGKVLVSGI
VGVLAFLLFTERLQIIVEGPTTLNYYWVPFLTLVFGSYMIAHGFFSVYSMCVETIFICFL
EDLERNEGSPSRPYFVTPALMNILLEQGKIKKQ-----------------

------------------------------------------------------------
------------------------------------------------------------
----------------M-SDKGQPPDTYLENKKYGNPRTFDPNFKGPVANRNCTDVLCCI
IFM----LFIIGYILLGLIAWVHGDPRKVAFPTDSQGHFCGQKGTPTENKSILFYFNLFS
CTSPSVMVNLQCPTT-QICVSKCPEKFLTYVETQFPYKKDKRSWTYFSQFCKSPFSKPEK
TLSQMLMDDDCPTVIFPSKPLLQRCFPDFSYINGTLTVGNKTMFEDGKGRTRNAAELRTA
A-KSINKILDAKAIGVKVFEDYATTWYWILIGLTIAMLLSWIFLILLRFTAGFLFWVFML
GVIGIIGY-EIWYCRYSL---------QDPTSHLTXXXXXXXXXXXXXXXXXXTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

IFMI
ILSILEVFIILTLIFLRNRIRISIALLKEGSKAIGYVPSTLVYPVLTFILLSICISYWAV
TA-VYLATSGVPIYKIIAPDGQCKHENKTC-DPE---IF--NTTEISRACPGAQCIFSFY
G-GKTLYHQYINTLQMFNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPEDIPPYPLFTAFGRAIRYHTGSLAFGSLILALIQMIRIILEYLDKRFKESQNNISKF-
----LQC------CLKCCFWCLE--------------------------------KVVKF
LNRNAYVMIAILGKSFCRSARDAF-NLLIRNIL-KVAI---MDKVTDFVLILGKMLVAGC
IGILAFLLFTQRIPMILEGPTSLNYYWVPLLTVVIGSYLIAHGFFSVYAMCIDTLFICFC
EDLERNDGSTEKPYFIAPTLHGILNKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------VSGEPRKFDPKFKGPIGKRHCTDVLCCI
IFV----VVILGYIALGVVAWIHGDPRKIIYPTDSYGQFCGQKGTPNENKTILMYFNILR
CASPVVLINLQCPTT-QLCVSKCPDRFATYLDMQAN-RFNNSYWEYYKQFCKPGFDKPRK
SITEVLRDEDCPSMIIPSRPFLQRCFPDFSTRNGVLTVANKTEFKDGIGQMRNVTDLRSA
AKSGINNVLDARSVGMKIFEDYASSWYWILIALFIAMVVSLLFLILLRFTAGVFFWIFII
GVIGVVGY-GIWHCFWEYDSLK-----GVPGADLTIYDIGLQTDFRVYLQLRQTWL

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMI
LLCIVEVIIILMLIFLRNRIRIAIALLQEGSRAIGYIMSTLFYPIITFILIAICISYWAV
TA-VFMATSGEPIYKVMANKTLCKYADITC-IPE---TF--NTTNVTRLCPGAQCTFAFY
G-GESFYHQYILIFQLCNVFVFLWLVNFSIA-----------LGQCTLAGAFASYYWAFK
KPADIPACPLFSSFGRAIRWLQRGFYSGHVVEKHCVLSCQL---LSNIVNGKLMVYVTIM
NVTQKYR------CSLCNMLPST--------------------------------KVLNF
C----YYFVFLF---FCDFALTVYTILYLLCVF-RVAV---LDKVTDFLLFLGKVFVTGS
VGVLAFFFFTRKIPVLTDEAPALNYYWVPLLTVLIGSYLIAHGFFSVYAMCVDTLFLCFC
EDLERNNGSSSKPYYMSPNLHRILGKKEILSKKAKR--------------

------------------------------------------------------------
------------------------------------------------------------
----------------MSV-EGSSSDLPSEGGKFGDPKTFEPDFKGPVNTRSCTDVLCCV
FFL----FFVFGYILLGLMAWVHGDPRRLAYPTDSQGHFCGQKGTPNENKSILFYFNLLK
CTTPSVMINLQCPTT-QICVSHCPERFVTYVEMQIRTKSNQTHWAYYKQFCKSSFVKPKK
SLTDILLEEDCPTAIFPSKP----------------------------------------
---GINRLLKVKSLGVKVFEDYSTSWVWILMGLLIGMLLSWMLLILLRYTAGSLSWISML
GVLRLVGY-GIWHCYREYKKLQ-----GKPTSELTIYDIGIQTDLSIYFELKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 899)

AFMI
ILCIVEGFITIMLIFLRNRIRFAVALLKEGSKAVGCIPSTLIYPVLTFILIAICISYWAV
TA-VFLATSGVPIYKVMTPGGQCIHENKTC-DPQ---TF--NTTDISKICPGAMCNFAFY
G-GKSLLHQYITVFQIYNLFAFLWLINFVLA-----------LGQCTLAGAFATYYWATK
KPEDIPPFPLFTAFGRAIRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAQNNISKF-
----LQC------CLRCCFWCLE--------------------------------KMVKF
LNKNAYIMIAIYGKNFCKSAKDAF-NLLMRNVV-RVAV---MDKVTEFVLILGKILVTGS
IGVLAFLFFTQRVPVIIKGPTSLNYYWAPLLTVILGSFLIAHGFFTVYAMCIDTLFICF-
--------------------------------------------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTASEEEDFGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLMIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLNHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKPPSSQGDPRRYDPDFQGPTAKRTCTDVLCCL
IFL----LFILGYVLLGLLAWAHGDPRKMAYPTDSQGHFCGQKGTPNENKTVLFYFNIFR
CTSPSMMLRLQCSTT-QICVSRCPERFLTYLDMQFLNKEDKNYWEYYRQFCKAK-AKPVE
TLRDLLISGDCPLAVYPSRPFLQRCIPDLSALNGTWTPGSRMKFEDGSGQTRTMLEFREA
A-NGISDLINARTIGLKLLEDYATSWKWILIGLTVAMALSWTFLILLRFTAGFLFWFFIF
GVLGIIGY-GIWYCFLEYSSIQ-----QRPQSTFWMYGFGIQRRVNMFFHLKETWFSMM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSAIEIIIIIVLIFLRTRIQVAIILLQEGSKAISYLPSALIYPVLTFILLSICISYWAV
TA-VFLATSGVPIFKVMVPAGQCIYEDETC-DPE---IF--PYTNIPKDCPGASCNFAFY
G-GRSMYHNYILTFQVYNLFAFLWLINFVIA-----------LGQCALAGAFASYYWAMK
KPDDIPPYPLFTAFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRLKKAQNSAAQF-
----LHC------CLQCCFWCLE--------------------------------KMVKF
LNRNAYIMIALYGKNFCESTRDAF-YLLMRNIL-KVTV---TDEVTYFVLLLGKVLVSGI
VGVLAFLLFTERLQIIVDGPTTLNYYWVPFLTLVFGSYMIAHGFFSVYSMCVETIFICFL
EDLERNEGSPSRPYFVTPALMNILLEQGKIKKQ-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--L----LLIAFLSFLVPAAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLMIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFT

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

LMI
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVVA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------DPRTYDPDFKGPVVSRSCTDVVCCM
IFL----VFIMGYILLGLMAWTNGDARRVTYPTDSQGHFCGQKGTPNENKTVLFYFNLLR
CASPSVMINLQCPTT-QICVSKCPETFLTYVEMQILYKKNSSYWEYYRQFCKST-AKPAK
SLPEVLMDDDCPTAVFPSKPFLQRCFPDFVNKNGTLTVGNRILFEDGSGRMRNVLELREA
T-NGINKILDAREIALKVFEDYATTWYWIIVGLTIAMILSWTFLILLKFIAGCLFWFFVL
GVLQVVGY-GILYCFQQYTKLQ-----EHPESSLTLYNIGIETNISMYFQLKQTWFILM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCILEVTIILLLIFLRKRIHLA---------AIGYIPSTLVYPVLTFILLSICFSYWIV
TA-LFLATSGVPVYKVSAPEGQCVHENETC-DPR---IF--NTTDVPKACPGALCNFAFY
G-GKSLYHQYISTLHLYNLFVFLWLINFVLA-----------LGQCTLAGAFASYYWAMK
KPDNIPALPLFKAFGQAVRYHTGSLAFGSLILALIQMFKVILEYLDRRLKSAQNNISKF-
----LKC------CLGCCFWCLE--------------------------------KMVKF
LNKNAYIMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---TDEVTHFVLLLGKILVSAL
IGVLAFLLFTEKMPVILGGPTSLNYYWVPLLTVILGSYLVAHGCFSVYATCVETIFLCFL
DDLERNEGSAARPFFVSSSLMQILLNKDSTKNKW----------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------NPRTYDPDFKGPVVNRSCTDVVCCM
IFL----VFIMGYILVGLVAWAHGDARRVTYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVMINLQCPTT-QICVSKCPEKFLTYVEMQILYKKNSSYWEYYRQFCKAT-AKPAK
SLPELLMDDDCPTALFPSKPFFQRCFPDFTSTNGTLTVGNKVQFEDGSGRVRNVLELKEA
V-NG----------------------------LTIAMVLSWTFLILLRFIAGCLFWLFMF
GVLHVIGY-GILYCYQQYNKLQ-----RNPKSSLSLYDIGIQTDINMYFQLKETWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
TLCILEVTIILLLVFLRKQIRLAIVLLKEGSKAIAYLPSTLVYPVLTFILLSICFAYWIV
TA-VSLATSGVPVYKVSAPEGQCTHENETC-DPM---IF--NTTDVPKTCPGALCNFAFY
G-GKSLYHQYITTLHLYNLFLFLWLVNFVLA-----------LAQCTLAGAFASYYWAMK
KPDDIPRLPLFTAFGQAVRYHTGSLAFGSLILALIQTFKVILEYLDRRLKKAENVVSKF-
----IKC------CLICCFWCLE--------------------------------KLIKF
LNKNAYIMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---TDEVTHFVLILGKILISAL
IGILAFLLFTEKMPVNFGGPTSLNYYWVPLLTVILGSYLVAHGCFSVYATCVETIFLCFL
EDLERNEGSAARPFFVSPSLMKILLEQDSTKDQW----------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMMFQDGNGGTRSVVELGIA
A-NGINKLLDAKSLGLKVFEDYARTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----ERPSSVLTIYDIGIQTNISMYFELQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPGGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKLLVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFVTPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------CCM
IFI----LFIVGYILLGLVAWIHGDPRRVAYPTDSEGHFCGQKGTPNENKPVLFYFNLFR
CTNPSMMLRLHCPTT-QVREGEMV-CFFSYYDFQHLNNVN---------------FLLFQ
SLSEIFMRGDCPTAVFPSRPFLQRCFPDFSSTNASLTVGHKITFEDGSGNVRNVVELREA
S-NGRGLTL-----------SLLGGWAWCD-CLTIAMVLSWIFLILLRYIAGLLFWVFMF
GVLGIIGY-GIWFCFMEYNRLQ-----QKPESTITIYDIGIQADISMFFYLKQTWFILM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSIIEGIIIIVLIFLRKQIRIAIVLLKEGSKAIGYVPCTLAYPLLTFILLSICISYWIV
TA-VFLATSGVPVFKVIAPEGQCAYEDETC-DPE---NF--DNTDVHKVCPEASCNFAFY
G-GTGVYHKLNMTFQIYNLFAFLWLVNFVIA-----------LGQCTLAGAFCTYYWAMR
KPDDIPPHPVFTSFGRAVRYHTGSLAFGALILASVQMFKVIIEYVDRRLKSKHLQGLHV-
----S---------------------------------------------------NKTN
KTIDCLPQIAMYGKSFCESTKDAF-NLLMRNIL-KVAV---TDEVTHFILFLGKILVSGF
VGILAFLLFTERLQKIIEGPTSLNYYWVPLLTIVCGSYLIAHGFFSVYSMCIETIFICFC
DDLERNDGSAEKPYFITPTLHRILTKKRPVPPKYSRKAPSSAAHFEVRVL

------------------------------------------------------------
----------------------------------MAKKR-----------KPPS------
--TQEE-----------------SPDSTSEEEDFGQARPHDPDFKGPVVNRNCTDILCCI
IFL----LFIIGYILLGLVAWVHGDPRRVAYPTDSQGHFCGQKGTPNENKTVLFYFNLLS
CASPSVMVNLQCPTT-QICVSKCPDKFITYLEMQFLYKKDKSYWEDYRQFCKTN-AKPVK
SIPQLLLDDDCPTAVFPSKPFLQRCFPDFSTKNGNLTIRSRMLFEDGYGRTRSAIELREA
V-HRINKIFEARTLGMKVFEDYATTWYWILIGLSIAMVVSWMFLVLMRFIAGLIFWIFMF
GVLGIIGY-GIWYCFQQYSILQ-----EHPNSTLSIYDIGIQTNISLYFQLQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSIIEASVILLLIFLRNRIRIAIFLLKEGSKAIGHIPSTLIYPFLTFILLSICISYWVV
TA-IFLATSGVPIYKVIAPEGQCIHENKTC-DPE---IF--NTSEIAKACPGALCNFAFY
G-GKTLYHQYIPAFHVYNLFVFLWLINFVIA-----------LGQCTLAGAFAAYYWAAK
KPDDIPPHPLLTSFGRATRYHTGSLAFGSLILASIQMLKMVLQYVDKRLKNAQNKFSKL-
----LQC------CLKCCFWCLE--------------------------------KVVKF
LNRNAYIMIAIYGRNFCRSARDAF-NLLMRNIL-KVAV---TDEVTYFVLFLGKILISGS
MGILAFLFFTRKMPMIEVGPTSLNYYWVPLLTVTLGSYLIAHGFFSVYAMCVETIFLCFL
DDLERNDGSTTRPYYVSPSLLKIFQDNYSRTKKR----------------

------------------------------------------------------------
----------------------------------------------------MS------
--NTEK-----------------TADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRATYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVMLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPAK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSRVVFQDGNGKTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMFLSWIFLILLRFIAGCLFWVFII
GVIGIIGY-GIWYCYQEYTKLQ-----EHPSSVLTIYDIGIQTSISMYFQLKQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVTVILMLIFLRNRIRVAIILLKEGSKAIGYIPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTSFGRAIRYHTGSLAFGSLIIALIQMFKIILEYLDHRLKRTQNTLSKF-
----LKC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAV---TDEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPTSLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLIPQKQKE--------------

------------------------------------------------------------
----------------------------------------------------MS------
--DTEE-----------------PAGTPSEEEDFGDSRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVMLNLQCPTT-QICVSKCPQRFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPAK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSRMVFQDGNGKTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMFLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWYCYQEYIKLQ-----EHPSSVLTIYDIGIQTSISLYFQLKQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVTVILMLIFLRNRIRVAIILLKEGSKAIGYIPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCSFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTSFGRAIRYHTGSLAFGSLIIALIQMFKIILEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAV---TDEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPTSLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------ACRHCTDVPCCL
LFM----VFILSYVALGLVAWDQGDAKKVAYAVDSRGDFCGQKNTPNEMKSLLFYFNILL
CSSPVVLLKLHCPTT-TVCVSTCPDRFLTFLEVQGRYTFNRSLWAYYQQYCKPGFDNPLK
PALDVLRDQDCPPMIIPSRPYFKRCFPDLSIQDSILRIGNQTAFLDGSGILRNVSDLQEA
A-KDINLIRSMKILGFKILEDFASAWHWIVLALVLAMFSSFLFLLLLRFCASCILWIFVL
GVIGIVAY-GIGYSYLEYRHLH-----TSQGAQMTILDLGFHSDYKAYLKLEQTWLL

PF04515 // ENSGT00550000074521_4_Domain_2 (478, 546)

FLI
LLSIVELLVLFLLLFLRKSIRIAVILLEEGSRIIGHMPQSLLFPLVTVFLVFVCIGYWIV
IAM-Y

ENSGT00550000074521_4_Linker_2_0 (546, 676)

PSIIPFPSGIL------RQHQNQLLKIPSINDRFVIVTAEKPRKPGPESCSARLT
P-SR-----------SPHWPVILWTLCFLPCAILAVLPPPYPSGIQLLQGRERSITIALK
NKNILVPYFV----L

PF04515 // ENSGT00550000074521_4_Domain_0 (676, 908)

SLTRYHTGSIALGAITLTTVQCLRFFLEYINHHLKDSKRMQSKF-
----ILC------CCRFCLWCLE--------------------------------KFLKY
LNRNAYIMVAIYGDNFCTAAQDAF-HLVMRNVV-RVAM---LDKVTDFLLWLGKMLVSVS
IGALGYLFFTQKLPI---AAPTLNYYWIPLLVMVLGSYIIAHGFFSVFAMCVDTLFLCFC
EDLERNN

PF04515 // ENSGT00550000074521_4_Domain_4 (676, 908)

SLTRYHTGSIALGAITLTTVQCLRFFLEYINHHLKDSKRMQSKF-----ILC------CCRFCLWCLE--------------------------------KFLKYLNRNAYIMVAIYGDNFCTAAQDAF-HLVMRNVV-RVAM---LDKVTDFLLWLGKMLVSVSIGALGYLFFTQKLPI---AAPTLNYYWIPLLVMVLGSYIIAHGFFSVFAMCVDTLFLCFCEDLERNNGSLERPYFMPPTLLKTLGKRQYRKLKKK---------------

------------------------------------------------------------
------------------------------------------------------------
------------------FNKD--MILCYFILNTGEPRKFDPKFRGPIHNRHCTDVICCV
IFI----VVILGYIALGIVAWVHGDPRKVIYPTDSYGQFCGQKDTFNENKTILFYFNILK
CASPVVLINLQCPTTQQLCVSKCPDRFATYIDVQASYRYRPDQWNYFKQYCRPGFNNPRK
SVAQVLRDEDCPSMIIPSRPFLKRCFPDFSTKNGVLTVANQTTFKDGRGKTRNVTDLREA
A-NGINNVLDARSVGMKIFEDYAISWYWILIGLFIAMIVSLLFLVLLRFTAGVLFWIFIF
GVIGIIGY-GIWHCYWEYDHLK-----GIPGSDLTVYDIGFQTDFRVYLQLRQTWL

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMI
LLCVVEIIIILMLIFLRNRIRIAIALLKEGSRAIGYIMSTLFYPIVTFILIAICISYWAV
TA-VFLATSGEPVYKVMANQTLCKYANLTC-DPE---TF--NTTNVTKLCPGAQCTFAFY
G-GESLYHKYIFIFQLANAFVFLWLVNFAIA-----------LGQCTLAGAFASYYWASR
KPADIPLWPLFSSFGRAIRYHTGSLAFGALILAIVQLIRVILEYLDHKLKGTQNSFTRF-
----LLC------CLKCCFWCLE--------------------------------RFLKF
INRNAYIMIAIYGKNFCTSAKEAF-FLLMRNVV-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTQRIPVFAQEAPALNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTLFLCFC
EDLERNDGSTAKPYFMSASLHRILGKKELSPKKA----------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKPPSIQGDPRTYDPDFQGPTSDRSCTDLLCCV
IFT----LFVMGYILLGLVAWIHGDPRRVAYPTDSQGHFCGQKGTPNENKTILFYFNLFR
CTSPSMMLKLQCPTT-QICVSRCPEKFLTYLEMRFLNKKDKTQWEYYRQFCKAT-ASPAK
SLSDLLSRGDCPPAVYPSRPFLQRCLPDFSTINRTLIVGSRMQFDDGSGKSRNIIELREA
A-NGIGKILDARTIGLKVFEDYTTTWKWILIGLTVAMALSWIFLMLLRFTAGFLFWVFMF
GVLGIIGY-GIWYCYVEYIGLQ-----HKPQSAIMIYDIGIQTAINMIFHLKQTWFSMM

PF04515 // ENSGT00550000074521_4_Domain_3 (480, 556)

I
ILCVIEAIIIIVLIFLRRRIRVAIILLKEGSKAIGYIPSTLVYPVVTFVLLSICISYWAV
TA-IFLATSGVPIFK

ENSGT00550000074521_4_Linker_3_4 (556, 789)

VMVPEGGCIHEDETC-DPE---I----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------

PF04515 // ENSGT00550000074521_4_Domain_4 (789, 904)

-ALYGKNFCASTRDAF-YLLMRNIL-KVAV---TDEVTHFILLLGKILVSGI
VGVLAFLLFTERLQEIVEGPTTLNYYWVPFLTLVLGSYLIAHGFFSVYSMCVETIFICFL
EDLERNEGSPSKPYYVTPALKDLLMEPGEEKKNKKR--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKPPNIQGDPRMYDPDFQGPTADRSCTDVLCCM
IFI----LFVVGYILLGLLAWTHGDPRRVAYPTDSQGHFCGQKGTPNENKTVLFYFNLFR
CTSSSVMFRLQCPTT-QICVSRCPEKFLTYVEMQFLNKEDKSHWEYYRQFCKAT-ARPAK
SLSDLLTHGDCPPAVYPSRPFLQRCLPDFSTINGVLTVGSRMQIEDGTGRTRNIVELREA
A-MGISKIFDARTIGLKVFEDYATSWKWILIGLTIAMALSWSFLILLRFIAGFLFWVFMF
GVLGIIGY-GIWYCYQEYYGLE-----QKPQSTILIYDIGVQSSINMFFQLKQTWFSMM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
VLSVIEAVLIIVLIFLRSRIRVAIVMLKEGSKAIGYIPSTLMYPILTFILLSICISYWAV
TA-VFLATSGVPIFKVMVPEGKCIYEDETC-DPD---IF--PETNIPKVCPGASCNFASY
S-GNNEYHNYIMTFQMYNLFAFLWLINFVIA-----------LGQCTLAGAFASYYWAMR
KPQDIPKYPLFIAFGRAVRYHTGSLAFGSLILASVQMFKVILEYLDRRLKKAQNSVSKF-
----LQC------CLRCCFWCLE--------------------------------KMVKF
LNRNAYIMIALYGKNFCESTKDAF-YLLMRNIL-KVAV---TDEVTHFVLLLGKILVTGI
VGILAFLLFTERLERIVEGPTTLNYYWVPFLTLVVGSYLIAHGCFSVYSMCVETIFVCFL
EDLERNEGSPSRPYFVTPTLMKLLMERKTDKKH-----------------

------------------------------------------------------------
------------------------------------------------------------
-------------------MSDEGKSADDYLELFGERKTFDPNFTGPVVDRCCTXXXXXX
XXX----XXXXXXXXXXXXXWEHGDPRRVAYPTDSNGHFCGLKGTPNENKSILFYFNLFS
CTHPAVLINLRCPTT-QICVSKCPNKFFTYTEIQYKYPKDKEYWTYYKQFCKSNISEPSK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXHVNKILEARAIAVKVFEDYAITWHWILIGFTVAMILSWFFVVLLRFIAGLLFWVFML
GLIVVLGY-GIWHCYHEYNSLQ-----EKPVPQLTMYSIGIQTDISMYFHLKETWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 899)

VLMI
ILCIFEVFIIIMLIFLRERIRLSILLLKEGSKAIGYIPTTLFYPFLTYLFLSICICYWAV
IA-IYLATAGIPIYKVVSPDGLCKYENNTC-SPE---VF--NATEIAKVCPGAHCNFAFY
G-GKTLYHQYISSFHIFNLFVFLWLINFIIA-----------LGQCTLAGSFATYYWTLN
KPDDIPSYPVFTSFGRAVRYHTGSLAFGSLILASIQIFKVTLEYLGTQIKDSENKVAKF-
----LQC------CLKCCFWCFE--------------------------------KVVML
LNRNAYIMIAIYGQNFCTSARDAF-NLLMRNAV-KVAV---MDQITDFILLLGKLLVTGC
VXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTVIGSYLIAHGFFSVYIMCIETIFICF-
--------------------------------------------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSQEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPVK
SITQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHSYQQYTNLQ-----ERPSSVLTIYDIGIQTNISMYFELQQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 908)

IFMI
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYIPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--HTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAV---TDEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFL
EDLERNDGSAARPYYVSQPLLKIFQEENPQTRKQ----------------

------------------------------------------------------------
------------------------------------------------------------
------------------MSDEEPPECPLDEDNFGKPRTFDPDFKGPVTKRYCTDVLCCL
IFI----LLIIGYIFLGLAAWVNGDPRRLAFPTDSQGHFCGQKGTPNENKTILFYFNLLK
CSNPSVMLNLQCPTT-QVCVSRCPEKFITYTEMQIKSKKNKTYWEYYKQFCKRHFDKPGT
SLSQIMLTEDCPTVIFPSRPFLQRCFPDFSTRNGTLTIGNKTTFHDGSGKKRNVIELRTA
A-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXALIIAMVLSWIFLILLRFTVGLLFWIFIL
GVLGVLGY-GIWYCYSEYIRLQ-----RDTTSDLSIYDIGIHSDVSLYFQLKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AXXI
ALSIIEILVILMLIFLRNRIRIAIALLKEGSKAIGHIPSTLFYPILTFIFLSICISYWAM
TA-VFLATSGTPVYKVVTPGGKCVHDNKTC-DPE---VF--NTSEIPKACPGSMCNFAFY
G-GTSLYHQYIPTFQIYNLFVFLWVMNFVIA-----------LGQCTLAGAFAAYYWALQ
KPDDIPPFPLFTAFGRAIRYHTGSLAFGSLILALVHMFRIVLEYLDRHLKDGQSSLAKF-
----LQF------CLKCCFWCLD--------------------------------KLIKF
LNRNAYIMIAIYGRNFCKSARDAF-NILMRNAI-KIAV---MDRVTDFVLFLGKILIAGS
IGVLAFLVFTQKIPMII-EPTTLNYYWVPLLTVIIGSYLIAHGFFSVYAMCVDTLFICFC
EDMERNDGSTEKPYFVAPKVHGILNELKLIPQEQKK--------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVVELGIA
A-NGINKLLDAKSLGLKVFEDYARTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----ERPSSVLTIYDIGIQTNISMYFELQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPGGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVTA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKLLVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFVTPNLHRILIKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------

PF04515 // ENSGT00550000074521_4_Domain_4 (788, 876)

MIAIYGKNFCTSAKDAF-FLLMRNVV-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTRRIPLFTQEAPSLNYYWVPLLVSKLFTV----------------------
--------------------------------------------------

------------------------------------------------------------
----------------------------------------------------MN------
--DTEK-----------------PADTPSEEEDFGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSQIVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLMIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----EHPRSVLTVYDIGIQTNISMYFELQQTWFTLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTENTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAVT---DEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
---------------------------------------MPYG-------VYKK------
--QQKD-----------------PSEEAVFVLNAGDPRTYDPDFKGPVSNRSCTDVLCCM
IFL----LCIVGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSVLLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSHWEDYRQFCKTT-AKPVK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSKMVFQDGNGGTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYATTWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMI
GVIGIIGY-GIWHCYQQYTNLQ-----AHPSSVLTIYDIGIQTNISMYFELQQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVV
TA-VFLATSGVPVYKVIAPEGHCIHENQTC-DPE---IF--NTTEIAKACPGALCNFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVVA-----------LGQCALAGAFATYYWAMK
KPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQNTLSKF-
----LQC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KCLKNCFTTKTIFLCKYIIYMFYVFN
VGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVILGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
---------------------------------------------MYLF-----------
-------VISL---------SNMLRKF--FILNAGEPRICDSDFKGPVVNRNCTDVLCCM
IFI----LFIIGYILLGLVAWVNGDPRRVAYPTDSQGHFCGQKDTPNENKTILFYFNLLS
CTSPSVVLNLQCPTT-QICVSKCPEKFLTYMEIQYMYRKDNSYLTYYSQFCKSAFVKPAK
TLTQVLLDNDCPTAIFPSKPFLRRCFPDFSTKNGTLTVGNKTEFEDGSGRRRNAVELRAA
A-NGINKALDARAIGMKVFEDYATTWYWILIGLTIAMFLSWMFVVLLRFTAGFLFWIFTF
GVIGIIAY-GIWNCYQEYNSLQ-----EKPNSHLTIYHIGVQTDISMYFQLRQTWFILM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCILEVFVILVLIFLRNRIRISIALLKEGSKAIGYIPTTLIYPVLTFIFLSICISYWAV
IA-VYLATSGVPVYKVITPKGQCIHENKTC-DPQ---TF--NTTEIAKACPGAQCNFAFY
G-GKSLYHQYITTFQIFNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAGIQMFRLILEYLDKRLKEAQNNISKF-
----LKC------CLRCCFWCLE--------------------------------KAVKF
LNRNAYIMIAIYGKNFCRSAKDAF-NLLMRNIL-KVAV---MDRVTDFVLVLGKILVAGC
IGVLAFLLFTERLPMIIEGPTSLNYYWVPLLTVIIGSYLIAHGFFSIYAMCIETIFICFC
EDLERNDGSTEKPYFIAPTLHGILNKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKPPSSQGDPRRHDPDFQGPTAKRTCTDVTCCM
IFL----LFITGYILLGLLAWAHGDPRKMVYPTDSQGQFCGQKGTPNENKTVLFYFNIFR
CTGPSMMLRLQCSTT-QICVSRCPERFLTYLDMQFLNKDDKNYWEYYRQFCKAK-AKPVE
TLGDLLSSGDCPLAVYPSRPFLQRCIPDLSAINGTWTLGSRMQFEDGSGQTRTMVELREA
A-NGISDVINARTIGLKLLEDYSTSWKWILIGLTIAMALSWTFLILLRFTAGFLFWFFIL
GVLGIIGY-GIWYCFLEYSSIQ-----QRPQSALWLYGFGIQRRVNMFFHLKETWFSMM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILSAVKIIIIIVLIFLRTRIRVAIILLQEGSKAISYLPSALIYPVLTFILLSICISYWAV
TA-VFLATSGVPIFKVMVPEGQCIYEDETC-DPE---IF--PNTNIPKDCPGASCNFAFY
G-GRSTYHNYILTFQFYNLFAFLWLINFVIA-----------LGQCALAGAFASYYWAMK
KPDDIPPYPLFTAFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRLKKAQNSAAQF-
----LHC------CLRCCFWCLE--------------------------------KMVKF
LNRNAYIMIALYGKNFCESTRDAF-YLLMRNIL-KVTV---TDEVTYFVLLLGKILVSGI
VGALAFLLFTERLQLIVEGPTTLNYYWVPFLTLVFGSYMIAHGFFSVYSMCVETIFICFL
EDLERNEGSPSRPYFVTPTLMNIFLEQGKIKKQ-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--M----LLIEFSSFLVPSAWTNGDARRVTYPTDSQGHFCGQKGTPNENKTVLFYFNLLR
CASPSVMINLQCPTT-QICVSKCPETFLTYVEMQILYKKNSSYWEYYRQFCKST-AKPAK
SLPEVLMDDDCPTAVFPSKPFLQRCFPDFVNKNGTLTVGNRILFEDGSGRMRNVLELREA
T-NGINKILDAREIALKVFEDYATTWYWIIVGLTIAMILSWTFLILLKFIAGCLFWFFVL
GVLQVVGY-GILYCFQQYTKLQ-----EHPESSLTLYNIGIETNISMYFQLKQTWFILM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCILEVTIILLLIFLRKRIHLAIVLLKEGSKAIGYIPSTLVYPVLTFILLSICFSYWIV
TA-LFLATSGVPVYKVSAPEGQCVHENETC-DPR---IF--NTTDVPKACPGALCNFAFY
G-GKSLYHQYISTLHLYNLFVFLWLINFVLA-----------LGQCTLAGAFASYYWAMK
KPDNIPALPLFKAFGQAVRYHTGSLAFGSLILALIQMFKVILEYLDRRLKSAQNNISKF-
----LKC------CLGCCFWCLE--------------------------------KMVKF
LNKNAYIMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---TDEVTHFVLLLGKILVSAL
IGVLAFLLFTEKMPVILGGPTSLNYYWVPLLTVILGSYLVAHGCFSVYATCVETIFLCFC
EDLERNDGSAEKPYFITPSLHEILVKKQSVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------RNCTDFVCCV
IFL----VFIMGYILLGLMAWAYGDPRRLTFATDSQGHFCGQKGTPYENKTTLFYFNMLR
CTSPSVVINLQCPTT-QICVAKCPEKFLTYVEMQILYKTDSRYWEYYRQFCKPT-AKPVS
SVPALLLNEDCPSMIFPSKPFLQRCFPDFIKENGTLTIGHRMHFEDGRGRMRTVLELREA
A-NGINKILNAREIAFKVFEDYATSWYWIVIGLTIAMILSWIFLVLLRFIVGFLFWFFVL
GVLHIIAY-GIFYCYQQYNKLQ-----KKPESLITLYNIGIQTNMTMYFQLKQTWFVLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILVILEMIIILLLIFLRRRIRLAIVLLKEGSKAIGYIPSTLVYPAFTFILLLICFSYWVV
TA-VSLATSGVPVYKVSAPEGPCVHENETC-NPT---NF--NATDVPKECPGALCNFAFY
G-GKSLYHQYISTLHWYNIFVFLWLVNFVFA-----------LGQCTLAGAFASYYWAMK
KPDDIPSLPLFTSFGQAIRYHTGSLAFGSLIIAVVHLFKMILEYLDRHLKNAQSHTSKF-
----LKY------CLTCCFWCLE--------------------------------KMVKF
LNRNAYIMIAIHGKNFCMSARDAF-NLLMRNIL-KVAV---TDEVTHFVLLLGKLLVTSF
IGLLAFLLFTEKTPAILGGPTSLNYYWVPLLTVILGSYLVAHGCFSVYTTCIETIFLCFC
EDLEGNDGSPEKPYFITPSLHEVLVKKQPVLQKQKK--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARRRKNPSIKGESKSSEPEFRRPVVERNFTDVLCCI
IFL----LFIMGYIVVGLVAWVHGDPRRVAYPTDSKGHFCGQKGTPNENKTILFYFNLLR
CAKPSILFGLQCPTT-QICVSKCPEKFLTYVEIQISYKGNNSNWLYYSQFCQPT-AEPEK
---------------------LQRCLPDFSTKNGSLTVGNKMLFEDGSGKTRNVLELREA
S-NAVNKILDARSIGSKVFEDYAVTWYWILLGLCTAMILSWTFLILLKFIAGFLFWIFAF
GVLGIVGY-GIWYCYEEYNNLQ-----HHPNSTLTIYDIGIETNISMYFKLKQTWFSFL

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILIIVEVIVIILLIAFRRRIRVAIVLLKEGSKAIGCIPSTLVYPVLTFFLLLICISYWVV
TA-VFLATSGIPMYTVTATDEPCIYSNKIC-EPE---SF--NTTEIPKVCPGAHCNFAFY
GGGKSLYHEYINTFHIYNLFVFIWLVNFVIA-----------LGQCSLAGAFAAYYWAMK
KPDDIPPFPLFTAFGYALRYHTGSLAFGALILSLIQIFKMVLEYMDSQLKKAQNSISKF-
----LQC------CLTCCFWCLE--------------------------------KMVKF
LNRNAYIMIAIYGKNFCISTRDAF-NLLMRNII-KVAV---TDEVTHFILFLGKILISGF
IGILAFLIFTQKIPTIIQGPTSLNYYWVPLLTVIFGSYLIAKGCFSVYSMCVETIFLCFL
DDLERNEGSKIRPYFVSQSLMKILMESDKKNQ------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------MARKRKPPSTQGEPRTYDPDFQGPTVNRRCTDVFCCF
IFL----LFIMAYIVLGLTAWLHGDPRRVAYPTDSQGHFCGQKGTPNENKSILFYFNLFR
CTNPTTMVNLQCPTT-QICVSKCPEKFLTYLEMQLLYYKDKSYWDYYSQFCKST-AQPVK
SLAEILIDDDCPTAIFPSRTFLQRCFPDFSTRSGNLTVGNKMRFEDGSGHMRNVLELREA
A-NGINKILDAKTIGLKVFEDYATTWSWILIGLAIAMVLSWIFLVLLRFIAGCLFWVFMV
GVHSIVGY-GILYCFQEYNRLQ-----QHPDSTLTIYDIGIQTNISMYFRLKQTWFMLM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
VLCIIEFAIIIMLIFLRNRIRLAIILLKEGSKAIGYMPSTLIYPLLTFILLSICISYWVV
TA-VFLATSGVPVYKVIVPEGSCVHANKIC-DPQ---IF--NTTDVPKACPGALCNFAFY
G-GKSFYYQYITTFHVYNLFVFLWLVNFVVA-----------LGQCALAGAFASYYWAMK
KPDDIPPYPLFTAFGRAIRYHTGSLAYGSLILALIQMFKIILEYLDNRLKRAQNSLSKF-
----IQC------CLKCCFWCLE--------------------------------KMVKF
LNRNAYIMIAIYGKNFCRSTRDAF-HLLMRNII-KVAV---TDEVTHFILLLGKLLVSGL
IGLLAFLLFTQRLSVIVEGPTSLNYYWVPLLTVVLGSYLIAHGFFSVYAMCVETIFICFL
DDLERNEGSSSRPYFVSPSLLKILLEQKGEQEHK----------------

------------------------------------------------------------
------------------------------------------------------------
--------------------MV--NERPSFFYARSEPRKFDPKFRGPIHNRHCTDIICCV
IFI----VVILGYIALGIVAWVHGDPRKVIYPTDSYGQFCGQKDTFNENKTILFYFNILK
CASPVVLINLQCPTT-QLCVSKCPDRFATYIDVQASYRYKPDQWNYFKQFCKPGFNNPRK
SVAQVLRDEDCPSMIIPSRPFLKRCFPDFSTKNGVLTVANQTTFRDGRGKTRNVTDLREA
A-NGINNVLDARSVGMKIFEDYAISWYWILIGLFIAMIVSLLFLVLLRFTAGVLFWIFIF
GVIGIIGY-GIWHCYWEYDHLK-----GIPGSDLTVYDIGFQTDFRVYLQLRQTWL

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMI
ILCVVEVIIILMLIFLRNRIRIAIALLKEGSRAIGYIMSTLFYPIVTFILIAICISYWAV
TA-VFLATSGEPVYKVMANQTLCKYANMTC-DPE---TF--NTTNVTKLCPGAQCTFAFY
G-GESLYHKYIFIFQLANAFVFLWLVNFAIA-----------LGQCTLAGAFASYYWASR
KPADIPLWPLFSSFGRAIRYHTGSLAFGALILAIVQLIRVILEYLDHKLKGTQNSFTRF-
----LLC------CLKCCFWCLE--------------------------------KFLKF
INRNAYIMIAIYGKNFCTSAKEAF-FLLMRNVN-RVAV---LDKVTDFLLFLGKILVAGG
VGVLAFFFFTQRIPIFAQEAPALNYYWVPLLTVIIGSYLVAHGFFSVYAMCVDTLFLCFC
EDLERNDGSTAKPYFMSASLHRILGKKELSPKKA----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------WMLSGLILAMISSLLFLMFLKYTAGVILWIFVF
GVVILIAY-GIWACYSEFHHLH-----TKPGT-PTLYEIGFQSDLRAYLKLKHTWL

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 908)

IFMI
LLCILEVIVLLALLFLRKRIQIAVALLKEASKAIGHIPHSLFFPLVTFFLVLMCIAYCTV
IAMSFLGTTGEAIYKVQSTDPNCKYTNEHC-DPE---TF--QSTNISSECPGVQCTFAFY
G-GKAFFYQYVLIFHIFNGFVFLWLVNFSIA-----------LGQCTLAGAFASYYWAFQ
KPNDIPPHPICAAFGRALRYHTGSLALGSLILSVVQFLRLILEYLDRRLKGKRHSCAKF-
----LLC------CLKCCFWCLE--------------------------------KFLKF
INRNTYIMIAIYGENFCASAKDAF-MLVMRNVV-RVAV---LDKVTEFTLWTGKLLISAG
IGILGFLFFTKSLPF---SAPTLNYYWIPLLVTIFGSYLIAHGFFSVFAMCVDTLFLCFC
EDLERNDGSLERPYYMSPKLLQILGKKQVTQEN-----------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------LLLIVLSFLVPTAWVNGDPRRVAYPTDSQGYFCGQKGTPNENKSILFYFNLLT
CTSPSVVVNLQCPTT-QICVSKCPERFLTYMEIQFKYKNDSEYWTYYSQFCRTTFLKPAE
TLSQVLLDNDCPSAIYPSKPFLQRCFPDFSTKNGTLTVGNKTVFDDGSGKTRNAAELRRA
A-NGINKALDARAIGVKVFEDYAMTWYWILIGLTIAMFLSWMFVMLLRFTAGLLFWIFTF
GVIGIIAY-GIWRCYLEYSRLQ-----EQPSSRLNAYTIGIQTDISMYFRLKQTWFA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

LMI
ILCLLELFIILMLIFLRNRIRISIALLKEGSKAIGYLPSTLIYPALTFFFLSVCISYWAV
VA-LYLATSGAPIYKVIAPQGHCEHENKTC-DPVVMQGF--NTTEVAKACPGAQCHFAFY
G-GKSLYHQYITTFQLLNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAIIQMFRLILEYLDKRLQEAQSNISKF-
----LKC------CLRCCFWCLE--------------------------------KAVKF
LNRNAYVMMAIYGKNFCKSARDAF-NLLMRNIL-KIAV---MDRVTDFVLILGKILVAGC
IGVLAFLLFTERLPVIIEGPTSLNYYWVPLLTVIIGSYIIAHGFFSVYAMCIETIFICFC
EDLERNDGSTEKPYFITPTLHGILNKKQLVPQKQKK--------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MKIFEDYASSWHWILIGLVIAMIMSLLFLVLLRFTAGVLFWIFIL
GVIGIIGY-GIWHCYWEYDHLQ-----GTPGSDLTIYDIGFQTDFRVYLQLRQTWLA

PF04515 // ENSGT00550000074521_4_Domain_0 (478, 908)

FMI
ILCIVEVIIILMLIFLRNRIRIAIALLQEGSRAIGYIMSTLFYPIITFILIAICISYWAV
TA-VFLSTSGEPVYKVMANQTLCKYANMTC-DPE---TF--NTTNVTKLCLGAQCTFAFY
G-GESLYHKYILIFQLSNVFVFLWLVNFAIA-----------LGQCTLAGAFASYYWAFR
KPADIPPCPLFSSFGRAIRYHTGSLAFGSLILAIVQLIRIILEYLDHKLKGTQNSFTRF-
----LLC------CLKCCFWCLE--------------------------------KFIKF
INRNAYIMIAIYGKNFCTSAKEAF-FLLMRNVV-RVAV---LDKVTDFLLFLGKLLVAGG
VGVLAFFFFTHRIPVFTQEAPTLNYYWVPLLTVIIGSYLIAHGFFSVYAMCVDTLFLCFC
EDLERNDGSTAKPYYMSASLHRILGKKELSPKKAMG--------------

------------------------------------------------------------
------------------------------------------------------------
--------MSD---------QGGLSDPYSEGKIYGDARTYDPDFKGPVAKRSCTDVLCCI
VFI----LFIIGYIILGLLAWVNGDPRRVAYPTDSQGQFCGQKGTSNENKTILFYFNLLS
CASPSVVVNLQCPTT-QICVSKCPEKFLTYMEIQFTYRRDRNYWAYYSQFCKSAVLKPAK
TLTQVLLDNDCPTAIFPSRPFLQRCFPDFSTQNGTLTVGNKTVFEDGSGRTRNAVELRAA
A-NGVNRVLDARAIGIKVFEDYATTWYWILIGLTIAMLLSWLFVILLRFTAGFLFWVFTL
GVIGIIAY-GIWHCYQEYSDLQ-----GQPNAHLTLYNIGIQTDISMYFQLRQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

AFMI
ILCILEVFVLLMLIFLRNRIRISIALLNEGSKAIGYIPTTLIYPVLTFIFLSICISYWAV
IA-IYLATSGVPIYKVITPEGQCKHENKTC-DPK---IF--NTTEVAKACPGAQCNFAFY
G-GKSLYHQYITTFQIFNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFNAFGRAIRYHTGSLAFGSLILATVQMFRLILEYLDKRLKQAQSNISKF-
----LKC------CLRCCFWCLE--------------------------------KAVRF
LNRNAYVMIAIYGKNFCRSARDAF-NLLMRNIL-KVAV---MDRVTDFVLILGKILVAGC
IGVLAFLLFTQRLPMIIEGPTSLNYYWVPLLTVIIGSYLIAHGFFSVYAMCIETIFICFC
EDLERNDGSTEKPYFIAPTLHGILNKKQLVPQKQKE--------------

------------------------------------------------------------
------------------------------------------------------------
-----------------MSDEEDSTDTSYENQDFGDPRSYDPDFKGPI-SRNCTDVLCCI
IFL----LFIFGYILLGLVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XICVSRCPEKFLTYMEMQILYRTNKSYWDYYRQFCKTT-AKPVK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XIWHCYHQYTILE-----ERPASTLTIYNIGIQIDISLYFQLKQTWF

PF04515 // ENSGT00550000074521_4_Domain_0 (477, 933)

ILMI
ILCIIELIIILMLIFLRKRIRVAIMLMKEGSKAIGYIPSTLIYPLLTFILLSICISYWAV
TA-LXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX---TF--NTTEIAKACPGALCNFASY
G-GKSLYHQYISTFQIYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAKK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILALVQMFKVILEYLDRRLRHAQNNVSKF-
----LQC------CLRCCFWCLE--------------------------------KMVKF
LNRNAYIMIAIYGRNFCRSARDAF-NLLMRNIL-KVAV---TDEVTDFVLILGKILVAGS
IGVLAFLLFTQRMPIITEGPTSLNYYWVPWLTVILGSYLIAHGFFSXXXXXXXXXXXXXX
EDLERNDGSTEKPYFITPNLHGILVKKQLAPKQK----------------

------------------------------------------------------------
----------------------------------------------------MS------
--NTEE-----------------PADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCM
IFL----LCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLR
CTSPSMMLNLQCPTT-QICVSKCPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTT-AKPAK
SLTQLLLDDDCPTAIFPSKPFLQRCFPDFSTKNGTLTIGSSMVFQDGNGKTRSVIELRDA
A-NGINKLLDAKSLGLKVFEDYVTTWYWILIGLTIAMFLSWIFLILLRFIAGCLFWVFII
GVIGIIGY-GIWYCYQEYTKLQ-----EHPSSVLTIYDIGIQTSISMYFELKQTWFTFM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCIIEVTVILMLIFLRNRIRVAIILLKEGSKAIGYIPSTLVYPALTFILLSICICYWVM
TA-VFLATSGVPVYKVIAPEGNCIHENQTC-DPE---MF--NTTEIAKACPGALCSFAFY
G-GKSLYHQYIPTFHVYNLFVFLWLINFVIA-----------LGQCALAGAFATYYWAMR
KPDDIPRYPLFTSFGRAIRYHTGSLAFGSLIIALIQMFKIILEYLDHRLKRTQNTLSKF-
----LKC------CLRCCFWCLE--------------------------------NAIKF
LNRNAYIMIAIYGRNFCRSAKDAF-NLLMRNVL-KVAV---TDEVTYFVLFLGKILVAGS
IGVLAFLFFTQRLPVIAQGPTSLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFC
EDLERNDGSTEKPYFITPNLHGILIKKQLVPQKQKE--------------

------------------------------------------------------------
---------------------------------------------MQKL-----------
-------AISKSQETTR-GDQRSDTRS--EGDKYGTPRAHDPHFRGPVVNRSCTDVLCCM
IFM----LFIMAYILLGLAAWVNGDPRRVAYPTDSQGYFCGQKGTPNENKSILFYFNMLT
CTSPSVVVNLQCPTT-QICVSKCPERFLTFMEIQFKYKNDSEYWTYYSQFCRTTFLKPVE
TLSQVLLDNDCPSAIYPSKPFLQRCFPDFSTKNGTLTVGNKTVFDDGSGKTRNAAELRKA
A-NGINKALDARAIGVKVFEDYATTWYWILIGLTIAMFLSWMFVMLLRFTAGLLFWIFTF
GVIGIIAY-GIWRCYLEYSRLE-----EQPGSHLNAYTIGIQTDISMYFRLKQTWFALM

PF04515 // ENSGT00550000074521_4_Domain_0 (480, 904)

I
ILCLLELFIILMLIFLRTRIRISIALLKEGSKAIGYIPSTLIYPALTFFFLSVCISYWAV
VA-LYLATSGAPIYKVIAPQGQCEHENKTC-DPV---GF--NATEIAKACPGAQCHFAFY
G-GKSLYHQYITTFQLLNLFVFLWLINFVIA-----------LGQCALAGAFASYYWALK
KPDDIPPYPLFTAFGRAIRYHTGSLAFGSLILAVIQMFRLILEYLDKRLQKAQSNISKF-
----LKC------CLRCCFWCLE--------------------------------KAVKF
LNRNAYVMMAIYGKNFCKSARDAF-NLLMRNIL-KIAV---MDRVTDFVLILGKILVAGC
IGVLAFLLFTERLPVIIEGPTSLNYYWVPLLTVIVGSYIIAHGFFSVYAMCIETIFICFL
EDLERNDGSAEKPYYMSQSLMKIMNRRNVETKKQ----------------