Query Results 

-------MERLQGVRAQLQAWERAFRRRHGRRPDQEDVRA-APQETRALYREYR-ALKEA
LGQAGDVGRRGPVQ--SLPAAAEEIPELGCWGSHLNRAATQSSHPS-PEQSS-RGSAQDY
GERIAN--LGAL-----QAGPALGRIPRPPRRTP-SM-PSTGP-------PDAGVTTVS-
P------KVSDVPSQPPRPQLRPGRLQQLQASLSLRLGSLNPDWLQRCHSGAPDFLGTPE
VCQPV-LGTEKPQ-----PQTSGVLSV--LGPST-----GPGE-----------------
--PLQGPEAPALPAARVSAGSPPLGSSQSKKQRQEGELEE-SPAQ---------------
AQQNSGHAGSLPGGAGAAALSGHCPGAPVQAQPRSPTARR---YHNF-GT-LSARV--ER
ALGTAHLCVPCRPAVCDRGNYVRLNMKRKCHVRGPALRGHLLRKQVYKQKWQKKRECFGG
GQPRT-TAK

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

DSCFRCGQLGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 629)

QTAGE-----------------------------
---------------------------------ENAQPGPPCP-PQPMPPLYQPGCSGQV
A---------ETPAEVFQALKQLGHQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQERAVMQVLSGMSTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPGLKAACVHSGMNRKQRNSALQKAR-A
AQVHVLMLSPEALVGAGAGGPACLA---QLPPVAFACIDEAHCL----SQWSHNFRPCYL
RICKV------------LREHLGVCCFLGLTATATHSTALD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VAQHLGVAKEHVLRGP-VI
IPPNLYLSVSMDRDPDQALVTLLQSDRFRSLDSVIIYCNRREDTERVSALLRTCLREAW-
------APGP

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

RGRVLEAVAEAYHAGMCSRARQRVQQAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLWELRRHVHANATDFLAV
KKLVQRAFPPCACPRQLSGQ--EGGESQDK-----------HSASAFVTESRRED-KQPG
NEHTVRCPGHKRALPVQPTVQALDLPEEVIETLLCYLELHPQHWLELLAPTHARCHLHCP
GGPTQLHALA--RRCPPLAVYLAKQPPEQMGR-GSCAVEFDVVELVDSMGWALGPVRQAL
RQLQWDPEARTGVPRGTGVTVEFRELALHLHSPGDLTVQEKDQICDFLYGRVQAREREAL
ACLNRTFQAFRSMALPNCGPFLEQPDEEHSARLKALLSQYFEEDGLG------GP---GD
EQGPEPEPAR-L--QDWEVQIRRDIRHFLSSWPEQQF----SGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKYL--------HLNFHALMQLATEEVLLWGR------------------
-----------------------------------------------------------

-------MERC

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 71)

REVRALLKAWEMAFLQEHKRKPNKNDVES-APEEMKELYREYR-ALRRD
QESAGLPQPS

ENSGT00550000074520_1_Linker_0_1 (71, 492)

SLGQ--KDAAA-EQAPELGCWGAHLNRKGTKPPPPTQM--APLRVPSKCY
GSTLKANLKADL-----QAGPRLGRIPRLPRRQQPEKCPSPKSRLSVPSAPTEAMPDPCE
ENTARLEPPVSPWGFGPRPVPQPGKLKHLQHTLGQRLSSLDPDWLQRCQVETREKLGRIE
HSSLL-SSPPGSPAETQNPYPEQEKGIELLNGRNLKSAPQGDAISSSPLPSETLETRPLC
GSPPGKEETPSTSKVRTLQRNP------TQKRKRGGSQDR-PPKQQKTGAKRL------G
TEPSGEQSKESEKVAALDNPEEDLLGEIVAQTAKTGTRA---------------------
-------RAPPRTFSKATGNFVRLNLKKKCYVKGFGLRGNRLRKQIWKKKWQMKSEQFGG
GWSRD-QGKDL

PF00098 // ENSGT00550000074520_1_Domain_1 (492, 506)

CFRCGAAGHWASQC

ENSGT00550000074520_1_Linker_1_2 (506, 630)

RATALPCHQPAKEESSETLEEQEEDEEPPLSTLQE
VAQRASSTSCQGPGSEERSRPVSPRGAVS---PRGPVPEPPAL-PPAVEPLYGLGPSGQL
A---------ETPSEVFAALTQFGHRTFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 713)

PGQEAAIMRILSGLSTLVVLPTGMGKSLCYQ
LPALLYARRSRCVTLVVSPLVSLMDDQ-VSGLPRGLRAVCIHSNMTRKQREA

ENSGT00550000074520_1_Linker_2_3 (713, 920)

AMEK----
------------------------------------------------------------
----V------------LRERLGVRSFLGLTATATRATARDVGQHLGIPEGAICGTHSAS
IPPNLHLSVSLDRDKDQALVTLLQGERFRTLGSIIVYCNRRDETVRVAALIRTCLQESPN
LGRSEESPGPRGLLPEAVA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

EAYHAGLPASERRRVQRAFMKGRLRVVVATVAFGMGLDRPD
VRAVLHHGLPGSIESYVQEIGRAGRDGLPAHCHLFLQPQGEDLRELRRHIYTDTVDYLTL
KKLVQRVFPPCTCSSLLQQLQVLNEEVLQEQSPSLHRQEKQEVPSSGGGDA--QEESELA
ASVQRACPGHERALSVQQMVEALDMREEAIETLLCYLELHPKNWLKLLAPTFATCHLKCY
GGPPELQAVA--KRCPPVAVSLTRQQAAKT--KGRSSLEFNVVELADSMGWEAALVRRTL
NQLQWEAAPGTRARRRTGVLVEFGDLSFHMQSPGDLTAFEKDEICDFLYQRIQTREREAL
TQLRATFQAFQRVAFPNCGPCMEHADEERSDQLKSLLTRYFEEGTAALWE---GEFREDS
EQDHDFGQAR-L--QDWESSVCSDIRQLLSIRQEEKF----SGRAVARIFHGIGSPRYPA
EVYGQDRRFWRKYL--------HVSFPSLLCLATREILAWKRT-----------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MKQKRYTRGRTLRGRLLRKQAWKQKWQKKGKCFGG
GGPRA-T-LEACLSCGQLGHWAPQ---CPQPV----------------------------
------------GE--EDTGPAGPELK------------VPHL-APAMLPLYPLGPLGQV
A---------ETPTEVFQGLEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQEHTVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYSQRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTKKQQESVLQKVR-A
AQLHVLMLSPEALVGAG--GPAIL---TQLPPVAFACFDEAHCL----SQWSHNFRPCYL
RICKM------------LRERMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 872)

TARDVAQHLGIVEELGLCG-PAP
VPANLHLSVSMDRDPDQALVTLLQGDRFRAL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSIIVYCNRREDTERVAALLRTCLCAVR-
------GPGPGDRAPEAVAEAYHAGMCSRQRQRVQRAFMQGQLRVVVATVAFGMGLHRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLRPQGEDLWELRRHVHANSTDFLAV
KKLVQRVFPPCTC--AQPPPEEQRGVGRER-----------PVAKCPVQKAEYHSSPQAA
PEPRRACPGHELALPVQPTVQALDLPEEAIETLLCYLELHPRRWLELLPTTYAHCRLRCP
GGPTELQVLA--HRCPPLAVCLARQPPEDTRW-DSRSLEFDMVELADSMGWELASVRRAL
RQLQWDQEPRTGVPRGTGVLVEFQELAFHLRSPGDLTAEERDQICDFLYGRVQARESEAL
TRLHRNFQAFHSMAFPSCGPCLEQPSEEQSTKLKDLLGRYFEEEAEEA----QGPEAMGD
EQGPELGQAM-L--QDWEDQIRRDIRQLLSLWPEEKF----SGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKYL--------HLSFHALMCLATEELLLVGR------------------
-----------------------------------------------------------

------------------------------------------------LYREYR-ALRRG
QVSR-----------------LYSAPELDCWGAHLNRNV-KPPLPTPP--ALLQEPLQCY
RMKLKSNLKAAL-----QAGSSSDRIPRLPRRAAKESSPK----SFVPSAPTEVIPNPCE
DPS------FPGL--------WTGLFQHLQHTLGQRLSSLDPGWLQRCQDGTR-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------DSGNFVRLNLKKKCYVKGFGLRGNLLRKQIWKKKWQMKGEQFGG
GWPRD-RGK

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

ESCFRCGDAGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 629)

GR--------------------------------
-------------GSEEEA---VSTHLVP---PRKPVFDPPLL-PRAVEPLYGLGPSGQV
A---------ETPSEVFETLTQFGHHTF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQEAAIMRILSGLSTLVVLPTGMGKSLCYQ
LPALLYAQRSCCITLVVSPLVSLMDDQ-VSGLPRGLRAVCVHSNMTRKQRETAMEKVM-T
GKAQVLLLSPEAVVGAGAGGFSCLPPAARLPPVAFACIDEAHCL----SQWSHNFRPCYL
RLCKV------------LRERLGVRCFLGLTATATRTTARD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VGQHLGIPEEAIFGVHLAT
IPPNLYLSVSLDRDKDQALVTLLKGERFGSLGSIIVYCNRRDETVRVAALLRTCLQESQ-
------IPGP

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

RGQLPEAVAEAYHAGLSASERRRVQRAFMQGRLRVVVATVAFGMGLDRPD
VRAVLHHGLPGSIESYVQEIGRAGRDGLPAHCHVFLQPQGEDLRELRKHIYADTVDYLTV
KKLVHKVFPPCTCSKVLQKLQEALEKES-------------STPKCPPQEE--GESGPQE
VPVCRACPGHERALSVQQMVEALDMREEAIETLLCYLELHPRNWLKLLAPTFAACHLKCY
GGLPQLQDLA--KRCPPVAVALARQQ---A--PGRSSLDFNVVDLADLMGWEAALVRRTL
NQLLWEVAPGKSGGNGTEGTVEYKDLSFHLQSPGD-TAFELDEICDFLHQRIQAREREAL
AQLRATFQAFQRVAFPNCGPCMEYVDEERSDQLKILLTRYFEEGTERLLR-----VREIN
EQDHDFGQAR-L--QDWESSICSDVRHLLSIREEEQF----SGRAVARIFHGIGSPCYPA
EVYGRDRRFWRKYL--------HVSFPSLLCLATRE------------------------
-----------------------------------------------------------

MERLRDVRERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 73)

DVRERLQAWERAFRRQSGRRPSKEDVEA-APEETRALYREYR-SLKKA
LGQAGGVEPHSSGQ--SLPAAAEQMLEPSCWGNHLNRAATQSPHPP-SRWSP-QESAQDC
GKRLKANLKGSL-----QARSTLGRIPRLAQRSSSKI-PSPEP-------TGTAAAPIS-
PE-----NVNQVLPQPPRPQLRPGRLQQLRASLSLRLGSLDPEWLQRCHNRTPDFLEVSR
TCQPG-LGAEDSQ-----LLTPA-------------------V-----------------
--PLQGPEAPALPAAGVSAGKCQPGDRQGKKRRQSGELEG-SLAQ---------------
TQQGTDQAGPLPEGAGAAGPAEDCPEQPVKTQPPGRTPAS---RYHC-SN-LPAGV--GR
AVGTADLCISSR-SVQDRGNYVRLNMKQRRYVRGRALRGRLLRKQAWKQKWQKKEECFGG
GQPRG-PAQDSCSQHGQLSHWASRCSQP--------------------------------
-------------AGEEDTEPGAPELLVP---TGPSVSRMPCP-PLSVPPLYPPGPSGQV
A---------DTPAEVFQALEQLGHHAFY

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 779)

PGQEPVIMRILSGMSTLLVLPTGAGKSLCYQ
LPALLYFRRSPCLTLVISPLTSLMDDQ-LSGLPPGLKGACIHSGMTKKQRDSALQKAR-A
ARVQVLMLSPEALVGPGAGT--LFS---QLPPVAFACLDEAHCL----SQWSHNFRPC

ENSGT00550000074520_1_Linker_2_3 (779, 873)

YL
RVCQGNVQGWLTAPSQTLRDQMGHCPRRGLAP----------GYH---------------
----------SCQPAPLSLPPSSLHDRFRALD

PF00271 // ENSGT00550000074520_1_Domain_3 (873, 986)

SIIIYCHRREDTERVAALLRTCLHEAR-
------DLGPHGRALEAVAEAYHAGLCSRDRRRVQRAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPSSFENYVQAVGRAGRDGQPAHCHLFLRPQGQDLRELRRHVHANAVDFFAV
KRLVQRVFPPCSCAR--QPPEQEGGRSKEE-----------CLAGAPVAASAQDP-GQPS
VPHTPRCPGHERVLPVQPTVQALDMPEEAIETLLCYLELHPRRWLKLVAPTYARCHLRWP
GGPTQLQALA--RRCPPLALCLAQQHPDTK-G-GCSSVELDLVKLADSMGWKLGPVRRAL
LQLQWEPEPETGVPQGTGVLVEFREMAFHLYSPGDLTAQERDQICNFLHSRVQAREQQAL
AHLHHTFRAFHSVAFPSCGPCLEQPDWERSSRLKALLSHYFEE-S-E------QPGGLET
EDDPELGQDR-LQ--DWEDQIRRDIRQLLSSWPEQRF----SGRAVARVFHGIGSPCYPA
QVFGRDRRFWRKYL--------HLSFPALMHLATQELLLWGR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 64)

DVRERLQAWERAFRRQRGRRPSQDDVEA-APQETRALYREYR-TLKRT
VGQAGG-GPRSSEL---LPVAVEEAPESHCWGPHLNRAATHSPQHT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRSSSKT-PTPNP-------PGTGPVPTF-
AE-----KVSDEPPQPPGPQSRPGQLQHLQASLSQQLASLDLDWLQRRHSEIPDFLGAPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSPDPEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPAQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPPQPCSSLSTPRYHRFSTSSQARA--GK
AEGTAHLHI-SRLARHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWQKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPAGPEPLVP---APQPVPGVPGL-ASTMLPLYPLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLSPATKLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVNEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRAPKTTAEAYHAGMCGRERQRVQQAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGTMGGER-----------PVPKYSSQEAEELGVHQAA
PGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPRHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ARLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDWRFWRKYL--------NLSFHALVRLATEELLRVAC------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 64)

RDLRTQLLAWERAFGKRHGRRPVQADVEE-APEDTRALYREYR-ALKRI
LGQAGG-GPRNPDP--SLPTEAEEALESNCWGPHLNRAAARSPEPE-PARRC-RGLVQDY
GGRLKANLRGAL-----KVGDA-GGQPLPPQRPASRT-TSPKP-------SDPEAILLS-
PN-----EASDVQLKPSGPQPRPGRLQQLQASLNLRLVSLDPGWLQRCHTGASDFLGAPK
ACRSG-LGSEESQ-----TLNFGAVAT--LGPGT--------------------------
--GSEGSEVSGLQATQGVSRSPQPSKRKSNKPRWSEEPWA-SPAQ---------------
VEQDSGQAEPLCDRGGAVALEEDPAGKPAPGQPPLPCISPLAPRYRGFSQGSKGR----V
AEGMSHLHISFRSAVKSKGNYVRLNMKHRRCTRGQALRGRLLRRQARMQKWKKRGECFRT
GESRT-T-VTACLSSGQLGHWAQQ---CPQST----------------------------
------------AE--EDTESARPEPW------------VPRL-VPAVPPLYLPGPSGQV
A---------ETPPEVFHALEELGHQSFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERTVMRVLSGISTLLVLPTGAGKSLCYQ
LPALLYSRRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVQ-A
AQVHVLMLSPEALMGSG--GPASLPHAVQLPPVAFACVDEAHCI----SQWSHNFRPCYL
RICKM------------LREHLDVHCFLGLTATATHS

ENSGT00550000074520_1_Linker_2_3 (818, 920)

TARDVAQHLGVVGELSLLG-PAP
IPANLNLSVSIDKDPDKALVTLLQGDRFRTLDSIIVYCNRREDTERVAALLRTCLCAVQ-
------GLGFGGCAPEAVA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

EAYHAGLCNRERQRVQQAFMRGQLRVVVATVAFGMGLHRPD
VRAVVHLGLPPSFENYVQAVGRAGRDGQPAHCHLFLQPQGQDLQELCRHVYADSTDFLAV
KKLVQCVFPPCTC--AQLPPVQQRGVGGDR-----------PMAKSTLQEAEHCSSSRAA
PGPRRTCPGHELALPVQPTVQALDLPEEAIETLLCYLELHPQHWLELLAITYARCHLCCP
GGPTQLQALA--HKCPPLAVCLARQSPEDTRQ-GSTSMEFDMVELADTMGWKLASVQRAF
RQLQWDQESRTGVRQGTGVLVEFRELAFHLRSPGDLTSEERDQICNFLYGRVQAREREAL
TRLHRNFQTFHSVAFRSCGPCLEQPSEEQSTTLKALLGRYFEEEAEAA----LGPEPVGD
KQGPEQEQAMVL--QDWEDQIRHDIRQLLILHPEEKF----SGRAVARIFHGIGSPCYPA
QVYGRDCRFWRKYL--------HLSFNALMRLATEELLLVGR------------------
-----------------------------------------------------------

-------MERLRDVRGRLQAWEREFARLHGRRPFS----------------AYR-TLKQA
VRQACG-AARSSGP--PLPAVTQEAPEPSCWGPHLNRAATQSPQLT-VAQSRWASSVQDY
GKRLKANLKDTTLQ---VTGGTLGRRFQSSQRPLSKV-PTPRP-------PDAKTTSTH-
AD-----EIGDVFLQPSGPQPMPGRLQRLQASRRLGLGSLDPHWLQRCQNMASDFPEAPS
ACWPG-LGAEESH-----SVASGDLAI--LGPDT-----QAEA-----------------
--SPPGPEASSPQAARVALGSPPLSN-SKKKWKWSKENWG-SPAQ---------------
GHWVSSHTAPEGAVAMASALEKDSSEEQIEVKPPQPHSSSS-----------GVRA--EK
AEVMAHMHTPPRPAGLDRGNYVRLNMKQKRYVQGRTSRGRLLQKQVQKQKWQKKGERFRG
GRLRA-TVEDSCFQCGKLGHWASHCPQPGPST-I------Q-KEGSKDKDGVQPSSALDK
AAQLTGTTYSHPPG--EDTEPTEPQLQAP------------H-PSHSVRPLYPPGPSGQV
A---------ETPLEVFQALKQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 816)

PGQEQAIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYGQRGPCVTLVVSPLLSLMDDQE-SVLKKV------------RRALHTVYSVQ-A
AQVQVLLLSPEALVGVGTRSPGALPQAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LREQLGVRCFLGLTATAT

ENSGT00550000074520_1_Linker_2_3 (816, 871)

RGTARDVAWHLGVSEDLDLVGTSPT
IPANLHLSVSMDRDPEQALVTLLQSDRFRS

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIVYCNRRETTERVAALLRTCLCVER-
------GPGPRGQAPEAVAEAYHAGMCSRERQRVQRAFMKGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLHPQGEDLQELRRHVHAASTDFLVV
KKLVQRVFPPCACPWL-------------------------PVAKS----KARPSGQQAA
RVPGPACPGHERALPVQPTVQALDLPEEAIETLLCYLELHPQRWLELLPAIYAQCHLHCP
GGRTQLAHLA--HKSPLVAACWARWPPEDACG-GSCSLKLDVVELAESMGWELVSVQRAL
YQLQRDPGPRTDTLRDTRVFVEFKELAFHLRSPGDLTAEQKDQICDFLHNCVQARERKAL
ARLRRIFETFHSMAFPSCGPCLEQPDQECNTRLKALISHYFEEEEEE---------GVEE
EQGSEPGQVQ-V--QDWEDQIRRDTRQLLSLWPEQSF----SGRAVARIFHGIGSPRYPA
QVYGQDRRFWRKYL--------HVSFRAVMRLATEELLVRDR------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MKQKRYTRGRALRGRLLRKQAWKQKWQKKGECFGG
DGPRA-T-VKACLSCGQFSHWAPQ---CPQPD----------------------------
-------------E--EDTRPAGPEPK------------VPHL-APAVLPLYPLRPSGQV
A---------ETPTEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQEHTVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYSRRSPCLTLVISPLLSLMDDQ-LSGLPPCLKAACIHSGMTRKRQESVLQKVR-A
AQLHVLMLSPEALMGAG--GPAIL---TQLPPVAFACVDEAHCL----SQWSHNFRPCYL
RVCKM------------LREHIGVQCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 872)

TARDVAQHLGIMEELGPCG-PSP
IPANLHLSVSMDRDPEQALVTLLQGDRFRAL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSIIVYCNRREDTERVAALLRTCLCAVR-
------GPAPGDHAPEAVAEAYHAGMCSRERQRVQRAFMQGQLRVVVATVAFGMGLHRPD
VRAVLHLGLPSSFESYVQAVGRAGRDGQPAHCHLFLRPQGEDLWELRRHVHANSTDFLPV
KKLVQHVFPPCTC--AQPPPEEQGGVGGER-----------PVAKSPIQKAEYHSSPQAA
PGPRRACPGHELALPVQPTVQALDLPEEAIETLLCYLELHPQRWLELLPNTYARCRLRCP
GDPTQLQALA--HRCPPLAVYLARQPPADTRR-DSRSMEFDMVELADSMGWELASVRRAL
RQLQWDQEPRTGVPRSTGVLVEFQELAFHLRSPGDLTAEERDQICDFLYGRVQARESEAL
TRLHRNFQAFHSMAFPNCGPCLEQPSEEQSTKLKALLGRYFEEEAEEA----QGPEAVRD
EQGPELEQAM-L--QDWEDQIRRDIRQLLSLWPEEKF----SGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKYL--------HLSFHTLMCLATEELLLVGR------------------
-----------------------------------------------------------

------------------------------------------------------------
---AGG-GPRSSE---LLPAAVEEAPESHCWGPHLNRAATQSPQPT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRSSSKT-PTPNP-------PGTGPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQASLSQQLASLDLDWLQRCHSEIPDFMGAPK
ACRPG-LGSEESQ-----LLTPGESAV--LGPGA--------------------------
--GSQDPEASALQEVSIGAGSPQPSSSRGKKQRRNKELWG-SPVQ---------------
VQQQSSHAGPPSEGAGAVALEEDPPGKPVQAQPPQPCSSSSIPRYHRLSTSSQARV--GK
AESTAHLHV-SRLARHDRGNYVRLNMKQKRYVRGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDRAGPELLVP---APQPVPGVPSL-ASTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 817)

PGQERAVMRVLSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLPPTTQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATR

ENSGT00550000074520_1_Linker_2_3 (817, 857)

RTAGDVAQHLAVDEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAVLLRTCLHAAQ-
------GPGPGGRAPKTMAEAYHAGMCGRERQRVQQAFMRGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGAMGGER-----------PVPKYPPQEAEQLGVHQAA
PGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPCHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAAWLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFTELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ALLRRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLRRYFEEVEEEA----QGPGGMED
TQGPEPGEAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAR------------------
-----------------------------------------------------------

------------------------------------------------LYREYR-TLKRT
TGQAGG-GPRSSE---SLPAAAEEAPEPHCWGPHLNRAATQSPQPT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRPSSKT-PTPKP-------PGTGPVPSF-
AE-----KASDEPPHPPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPE
ACSPD-LGSEESQ-----LLTPAESAV--LGPGA--------------------------
--GSQGPEASALQEVSFGAGSPQPSSSRGEKRRRNKEPWG-SPAQ---------------
VQQESSQAGPPLEGAGAVALEEDPPGEPIQAQPPQPCSSPSTPRYHRLSPSSQARA--GK
AEGTAHLHIFPRLACHDRGNYVRLNMKQKRHVRGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWLPFHPLLPAPA----------------------------
------------SE--EDTDPVGPGPLVP---APQPVPEVPSL-DPAVLPLYSLGPSGQL
A---------ETPAEVFQALKLLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 734)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYTQRSPCLTLVVSPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GSGGLPPATRLPPVAFALVPQLPALLSAWPGWAGRLTP-LL
PLGQV------------LRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPGLHG-PAP
VPANLHLSVSMDRDTDQALLTLLQGERFRNLDSIIIYCNRREDTERIPGTAA--------
---------------------------------GTAAFMQAQLRVVVPRWLSGWGWTGQM
CGLCCIWGCPQASRAT--CRPWAGPGWHPPNCQFA--LQGEDLRELRRHVHADSTDFLAV
KRLVQRVFPACTCTCTRLPPEQEGAMGGER-----------PVPKYPPQEAEQLGGHQAA
PGPRRACMGHERVLPIQLTVQALDMPEEAIETLLCYLELHPRHWLELLATTYTHCRLNCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVRLVDSMGWELASVRQAL
CQLRWDHKPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCGPCLEQRDEERSTRLKDLLGRYFEEE--EA----QGPGGMED
TQAPEPGQAR-L--QDWEDQVRGDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLNFHALVGLATEELLRVAR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 63)

DLRERLQAWERAFRQQHGRRPSQDDVKA-APEETRALYREYSSLKRTV
RQSGGG-GGPRSPE--SLPAAAEEAPEPHCWGPHLNRAATQSPQPT-PGRSC-QGSFRDY
GQRLKANLKGTL-----QASPALGHRPWPPERSSSKT-PIPKL-------PGTGLVPTF-
AE-----KVSDMPPQPSGPRPRPGRLQHLRASLSLRLGSLDPGWLQRCHSGVPDFLGAPK
PCRPG-LGSEESQ-----LLTTGESAV--LGPGA--------------------------
--RSQGPEASALQEVSIGAGSPQPSSSRGEKRRRNEVPWG-SPTQ---------------
VQQQSSQAGPPSEAAEAIALEEDSPGEPVQAQPPQPCSSRSTPRYHRLSPSSQARA--EK
AEGIAHLHIFPRMAGHDRGNYVRLNMKQKRYVRGRALRGRLLCKQARKQKWRKKGECFGR
GDTTV-TIKESCFLNGQFDHRAPQ---CPQPA----------------------------
------------SE--EDTDPDRPEPLVP---ALQPVPELPGL-APTVLPLYSLGPSGQV
A---------ETPAEVFHALEQLGHQDFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PRQERAVMQILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSRLPPCLKAACIHSGMTSKQRESVLQKVQ-A
GQVHVLLLTPEALV-----GAGGLPPATQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 858)

ASDVAQHLAVAEEPGLHG-PAP
VPANLHLSVSMDRDTDQ

PF00271 // ENSGT00550000074520_1_Domain_3 (858, 986)

ALLTLLQGERFRNLDSIIIYCNRREDTERVAALLRTCLHPAQ-
------GPGPKGRAPKTMAEAYHAGMCSRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGMDFWAV
KRLVQRVFPSCT--CARLPAEQEGARGGDI-----------PVAESPPQEVEQLGGRQAA
PGPRRACVGHERALPVQPTVQALDMPEEAIETLLCYLELHPRHWLELLATTYARCYLHCS
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVELVDSMDWELACVRRAL
YQLQWDHEPRTGLWRSTGVLVEFRELAFHLRTPGDLTAEEKDQICDFLYGRVQAREHQAL
AHLHRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLSRYFEEVEEEA----QGPGALGD
AQGPEPGQAR-L--QDWEDQVRRDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVFGQDRRFWRKYL--------HLSFHALVRLATEELLQVGR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 73)

DVREQLQAWERAFRRQRGRRPSQDDVEA-APEETRALYREYR-TLKRT
TGQTGG-GPRSSE---SLPAAAEEAPEPRCWGPHLNRAATKSPQPT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRSSSKT-STPKP-------PGTGPVPSF-
AE-----KVSDEPPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPK
TCRPD-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSQGPEASALQEVSIRAGSPQPSSSGGKKRRRNEEPWG-SPAQ---------------
VQQESSQAGPPSEGAGAVALEEDLPGEPVQAQPPQPCSSPSNPRYYGLSPSSQARA--GK
AEGTAHLHIFPRLARHDRGNYVRLNMKQKHYVRGRALRGRLLRKQAWKQKWRKKGKCFGG
GGATV-TTKESCFLNEQFDRWAAQ---CPRPA----------------------------
------------SE--EDTDPVGPEPLVP---SPQPVPEVPSL-DPTVLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYTRRSPCLTLVVSPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKIR-A
AQVHVLMLTPEALV-----GAGGLPPAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVAEGPDLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAR-
------VPGSGGHAPKTTAEAYHAGMCIRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFLAV
KRLVQRVFPACTCTCTRPPSEQEGAVGGER-----------PVPKYPPQEAEQLG-HQAA
PGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCRPCLEQQDEERSTKLKDLLGRYFEEEEEQG----QEPGGMED
AQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLSFHALVGLATEELLRVAR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 73)

DVRERLQAWERAFRQQRGRRPTQDDVEA-APEDTRALYREYR-ALKRT
TGQAGG-GPRSSE---SLPAAAEEAPESHCWGPHLNRAATQSPQPT-PGRSC-QGSVPDY
GQRLKANLKGNL-----QAGPALGRRPWPLGRSSSKT-PTPKP-------PGTGPVPSF-
AE-----KASDEPPHPPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPK
ACRPD-LGSEESQ-----LLTPGESAV--LGPGG--------------------------
--GSQGPEISAFQEVSIGAGRPQPSSSRGEKRRRNEEPWG-SPAQ---------------
VQQESSHAGSPSEGAGAVALEEDPPGEPVQAQPPQPCSSPSTPRYHRLSPSSQARA--GK
AEGTAHLHIFPRLARHDRGNYVRLNMKQKHYVRGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-EIKESCFLNEQSDHRAAQ---CPQPA----------------------------
------------SE--EDTHPVGPELLVP---APQPVPEVPSL-DPAVLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYTRRSPCLTLVVSPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLPPAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATHRT

ENSGT00550000074520_1_Linker_2_3 (819, 915)

ASDVAQHLAVAEEPGLHR-PAP
VPANLHLSVSMDRDTDQALLTLLRGERFRDLDSIIIYCNRREDTERIAALLRTCLHAAR-
------VPGSGGRA

PF00271 // ENSGT00550000074520_1_Domain_3 (915, 987)

PKTTAEAYHAGMCSQERRRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFLAV
KRLVQCVFPACT--CTRPPLEQEGAVGGER-----------PVPKYPAEEAEQLGGHQAT
PGPRRACMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELMATTYTHCRLNCP
GGPAQLQALA--HRCPPLAVCLAQQLPEDPEQ-GSSSVEFDMVKLVDTMGWELASVRRAL
CQLQWDHEPRTGVQRGTGVLVEFSGLAFHLRSPGDLTAEEKDQICDFLYGRVQAREHQAL
ARLRRTFQAFRSVAFPSCGPCLEQQDEERSTRLKDLLGRYFEEEE--A----QGPGGMED
AQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLSFHALVGLATEELLRVAR------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 125)

ATVRARLQEWERAFVRLHGRRPAKGDVEA-APEETRALYREYR-NLKQA
VRQADG-RHRVLEQ--SLAETAEEAQEPSCWGSHLNRAATQNTQSM-PKQSP-LSSVQDY
GKRL

ENSGT00550000074520_1_Linker_0_1 (125, 491)

KANLKNTP-----QTGPTLSRKLQPQKRSWSTV-PAPRP-------PGSRTESPC-
PD-----EANDALPLVPEPRPRLGQLQKLRSSLSLRLSSLDPGWLERCHNRVSDLLEAPG
ACGLD-LSAKESQ-----SQMSGKVNV--ADPDI-----QSEV-----------------
--SSQSPEALAQQPAQVLSQSPKSSDSKGRKRKWNE-KGE-DFAQ---------------
A-QPSSQAGPVSEGAGAPAHGKDPPGEPTQVNVPQPCNSSN-----------QART--EK
AKGTTHLHVSPRPASLDRGNYIRLNMKNKCFVRVGANRGRLLRKQVWKQKWKKKQAAFGG
SGPRA-TVKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGSTPTI------Q-EEGDR--DDKQPISTLEK
VAQRTGTTSCHHS--GEETEPVGPELQVP------------HC-PTPMSPLYPPGPLGQV
A---------ETPAEVFQALERLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAIMRILSGISTLLVLPTGAGKSVCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPSCLKAACLHSGMTKKQRESVLKKVR-A
AQVHVLIVSPEALVGCGARGPASLPQAAQLPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAQHLGIAGEFELSG-SAN
IPANLHLSVSMDRDSDQALVTLLQGDRFRT

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIIYCTRRKDTERVAALLRTCLSTVS-
------DSRPRGCGPEAIAEAYHAGMCSQERRRVQQAFMRGHLRMVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFMHPQGEDLWELRRHAHADSTDFLAV
KKLVQRVFPPCTCSQ--------------R-----------LM--SPPEDIREHKGQQRD
PVLGQTCPGHERALPVQSTVQALDMTEEAIETLLCYLELHPRHWLELLPCTYAQCHLHCP
GGSAQLQALA--HRCPPLAACCAKWPPNDTSQ-GRSSLEFDVVELADSMGWKLASVRQAL
HQLKWDPEPKRGAAQSTGVLVKFSELAFHLHSRGDLTDEEKDQICDFLYSRVQTREHKAL
AHLHQMSKAFRSVAFPSCGPCLEQSNEEHSNQVKTLVSYYFEEEEE-E-----EEETMTD
TQGPKPGQTQ-L--QDWEDQIRRDIRQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QVYGLDRRFWRKYL--------HLDFHALRHLATEELLLRGR------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------ARPAVGHQSLSPPGTSSKL-PSPEP-------PHTEAV----
--------VSSGPLQSSRPQPKPVRPQQLRASLSLRLGSLDPDWLQRCDREPDDPGTVTS
QPSIS---A----------------PH--TGPD---------------------------
--AYTDSEAPALQTVT-----SQSCTSEDKKRRQ-----S-EPYR---------------
AQEDQGAVGFPTHSAGPALVDEASPGVPTH-----PF-CTPVPRCHSPSPLRRAWV--NS
TLGKAHLCIPSRPTRHNRGNYVRLNLKHKHYMRGPALRGRFLRRQVWKQKWQKKEGLDR-
VRRRP-MSQ

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

DSCFKCGQLGHWGSECP

ENSGT00550000074520_1_Linker_1_2 (507, 629)

QHEDVETS------N-------------------
-----------------LQCPGSP---------QRHLPEAPC--PSPMLPLYQPAPSGEM
P---------ETPAEVFQALHHLGHQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 687)

RPGQEQAIMRILCGMSTLLVLPTGAGKSLCYQ
LPALLYFQRSPCLTLVVSPLLSLMDDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
--XXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXV------------LREQVGVHTFLGLTATATRSTTLDVAQHLGVAGP---GQGPTA
IPSNLQLSVSMDRDPDQALVTLLQSDRFRALDSVIVYCNRREDTERVAALLRTCLHGAR-
------R--P

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

GGQAPETIAEAYHAGMSSRERRRVQQAFMGGQWW-VVATVAFWMGLDRPD
VRAVLHLGLPSSLESYVQVLGRAGRDGQSAQCHLFLPPQGEDLLFL-THVHAQAFDFLAV
L-----------------------------------------------------------
---------------------------VPIETLLSYLELHPQHWLELQASTYSHCHLHFP
GGPAQLQALA--RRCLALAACVARQTPKSTPG-GGVSLDFDVVALADSMGWELRLVRREL
QQLQWDPELGTGASQGTGVLVEFRQLAFCLRSRGDLSPEETDDICSFLCGRVQAREQEAL
SRLRRTFQTFHSVAFPSCGPCLEQPDQERSSRLKALLSCYFEEEV---------PGVSEE
EQGPEPGQVQ-L--GDWEDQVCRDIRHLLSSWPEQQF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLNFHVLMQLATKEVLAWGR------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 88)

ASVRALLQEWERAFARLHGRRPAQEDVEA-APEETRALYREYR-NLKHA
VRQAGD-GHRSQEQ--SLAEAAEEAQK

ENSGT00550000074520_1_Linker_0_1 (88, 491)

PSCWGPHLNRAATQNTQPV-PRQGP-LSSVQDY
GERLKANLK----NAKLQTRPTLSRKLQPQKRSLSTA-TTPRP-------PGPR---TC-
PD-----ETNDILPRLPEPQPRLGQLQQLQASLSLRLSSLDPGWLERCHARVSDLLEVPD
ACGLD-LDAKESQ-----PQKSGKANV--LDPGI-----HSEK-----------------
--KSQSPDALALQP-----PSPTPSNDEDR--KWSK-DSE-DFAQ---------------
A-RDSSPAGQLSEGARTTAHEKEAPGEPAQVNALQPRSKQA--------------K--TE
AKGTARIHISPRAASLDRGNYVRLNMKQKCYVRVGASRGRLLRKQVWKQKWKKKREQFGG
SGPRA-TTRD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQSGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGSTLTF------Q-EEGGR--EDKQPDSALEE
VAQTTASPSCPLS--GQDTEPDGLKLQMP------------CP-PCPVLPLYPPGLLGQV
A---------ETPAKVFQALQQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPPCLKAACLHSGMTKKQRESVLKKVRRA
AQVQVLIVSPEALVRCGAKGPASLPDASQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 870)

TARDVAQHLGIAEEPELSG-LAP
IPANLHLSVSMDRDSDQALVTLLQGDRFR

PF00271 // ENSGT00550000074520_1_Domain_3 (870, 986)

TLDSIIVYCHRQKDTERVAALLRTCLSMV--
----------RGCGPEAVAEAYHAGMCSQERRRVQQAFMQGHLRVVVATVAFGMGLDRSD
VRAVLHLGLPPNFESYVQAIGRAGRDGKPAHCHLFLQPQGEDLWELRRHAHADGTDFLAV
KKLVQRVFPPCTCTR--------------R-----------------------HNSQQTH
PVLGKACQGHKRALPVQSTVQALDMTEEAIETLLCYLELHPRHWLKLLPYTYAHCRLCCP
GGPAQLQALA--HRCPPLAACWAKWPPKDTSR-GSSSLEFDMVELADLMGWELASVRQAL
LQLQWDQGPRKGAPRGTGVLVEFSELAFHLHSPGDLTDEDKDQICDFLYSRVQAREHKAL
AHLRQIAKAFRSVAFPSCGPCLEQSDEDRSSQLKTLLSHYFEEE-----------ETVKD
EQGPEPGQNQ-L--QDWEDHIRRDIRQLLSVRPEERF----SGRAVARIFHGIASPCYPA
QVYGQDQRFWRKYL--------HLDFHALMRLATEELLLSSR------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------MLSP-RGSAQDY
GKRLKTNLKVIL-----QAEPALGCRHQPPGRLLSKL-PTLKP-------LGPGTPPTF-
PE-----ELIDKLTKPSEPQPRPGRLQQLRESLSLRLSSLDPGWLHRCHNGPLDFLEASE
ACS-----MEESQ-----TLTPGELAV--FGSNT-----CLEA-----------------
--PSQGPDAPVPQATQTRAGSPQLSSHTVKKQRWTKENDS-SPVP---------------
AQWDSNQARLQSEGAGASVL-EDPTEDATQAHPRQLYSGTS----------RPAEV--GK
AEITPRSHTCSQTAIRDKGNYIRLNMKQKRYVRGGALRGRLLRKQAWKQKWQKKREHFGV
GGPRA-MVEE

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQFGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QLGPTLIS------Q-KEGDKDKGDTQTFPTLEE
VTQRINTACCHLPS--KDTEPAGPELQ------------APHT-VSSVLPLYPPGPSGQV
V---------ETPAEVFQALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERTVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVISPLLSLMDDQ-LSSLPPCLKAACLHSGMTRKQRDSVLQKVQ-A
AQVHVLMLSPEALVGAGSGGPVSLPQAAQLPPVAFACIDEAHCI----SQWSHNFRPCYL
RICKV------------LRERMGVQCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 872)

ARDVAQHLGMAEELGPRE-AAA
IPANLHLSVSTDKDPEQALVTLLQGDRFRTL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSVIVYCNRREDTQRVAALLRTCLYAVQ-
------DPKLRGRAPEDVAEAYHAGMCNRERQRVQRAFMKGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPSSFENYVQAVGRAGRDGQPAHCHLFLKPQGEDLQELRRHVHRDGADFLAM
KKLMRCVFPPCTCT--QRERKEGGGDNETK-----------PAAEALPVAAKQPDGCPAA
SGQGRACPGHERALPVQPTVQALDLSEEAIETLLCYLELHPQHWLELLPATYAHCRLYCP
GGTNQLQTLA--HRYPPVAACWARWPPKDTKQ-GSCSMEFNVVELVDSMGWELSSVRRSL
HQLQWDPEPRTGMLQGTGVLVEFGELAFHFRSPGDLTAEERDQVCDFLYSCVQTRECKAL
ARLRRMFQAFHSVAFPSCGPCLEQPDEERSAQLKTLLSHYFEEEEEEE-----DEEGVED
KQSPEPGQAQ-L--QDWEDQVRPNIRQLLSLWPEERF----SGRAVARIFHGIGSPCYPA
EVYGRDQRFWRKYL--------HLNFHGLMLLATEELLLAGR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 62)

DVRERLQAWERAFQRQRGRRPSQDDVEA-APQETRALYREYR-TLKRT
VGQAGG-GPRSSDL---LPVAVEEAPESHCWGPHLNRAATQSPQHT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRRWPLGRSSSKT-PTPNP-------PGTRPVPTF-
AE-----KVSDEPPLPPGPQPRPGQLQHLQASLSQQLASLDLDWLQRCHSEIPDFLGDPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGT--------------------------
--GSQDLEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPAQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPPQPCSSSSTPRYHRLSTSSQARA--GK
AEGTAHLHI-SRLVHHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWQKKGECFGG
GGATV-KIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPAGPELLVP---APQPVQGVPSL-PSTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLPPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LREHMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 915)

ASDVAQHLAVDEEPGLHG-PAP
VPANLHLSVSMDRDTDQALLTLLQGERFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRA

PF00271 // ENSGT00550000074520_1_Domain_3 (915, 987)

PKTTAEAYHAGMCGRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGTMGGAR-----------PVPKYSSQEAEQLGVHQAA
PGPRRTCVGHERALPVQLTVQALDMAEEAIETLLCYLELHPRHWLELLATTYIRCRLSCP
GGPAQLQALAHRHRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSLGDLTAEEKDQICDFLYGRVRARERQAL
ALLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAC------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------M-PSPGP-------PGAGAAPVS-
PE-----EVSEVPLQPPGPRLRPGCLQQLQASLSLRLCSLDPDWLQRCQNGAPDFLGASK
ACQPN-LGVEDSQ-----PLASGVPPV--LGPGT-----GPE------------------
--------TQALQTARVHAESPQPGNSQDKKWTWNGEPEG-SPAQ---------------
AQQDSSHAGPLPEEAGAPEHAEACPAEPVGAQPPSGPTAT--------------------
-----------RPAVRSGGNYVRLNMKQKRYVRGPALRGRLLRKQMWKQKWQKKGECFGG
GQPRA-TVKN

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQLGHWSSQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QSSETSTLEPA--QGAQESRENEDDVQTRLAADE
AVQRIGTAGCQQPVSEKDPEPAGPELLVT---VEQPVPRAPCR-PRPVPPLYPPGPSGQV
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 817)

PGQERVIMQILSGMSTLLVSPTGSGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKVACIHSGMTRKQRESALKKVQ-A
AQVHVLMLSPEALVGAGLGPSGCLP---QLPPVAFACVDEAHCL----SQWSHNFRPCYL
RVCKV------------LREHLGVRCFLGLTATATH

ENSGT00550000074520_1_Linker_2_3 (817, 920)

STSRDVAQHLGVAEELVLSEP-VT
VPANLYLSVSMDRDPEQALVTLLQSDRFRALSSIIVYCNRREDTERVAALLRTCLRASR-
------DPGPRGQIPEAIA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

KAYHAGMCHRERRQVQQAFMDGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPASLETYVQAVGRAGRDGQPAHCHLFLQPQGQDLQELRRHVYADTADFLAV
KKLVQCAFPPCTCAQAQQPPEKDGARGQKT-----------PVA-----GSLRDA-EQPN
SQHAARCPGHQRALPVQPLVQALDMPEEAIETLLCYLELHPRRWLELLAPTFARCHLRCP
GGAPQLLALA--HRCPLLAVCLAQQPPESTGG-GGCSVEFDVVKLADSAGWKLASAQRAL
RQLQWEPEPTTGARRDTGVLVEFRELAFCLRSPGDLTAHERDQICDFLYGHIQAREREAL
AGLRRTFQAFHSVAFPSCGPCLEQPSEEHSARLKALLSCYFKE---E------SPGDTED
DQDPEPGQAG-I--QDWEDQVRRDVRHLLSLWPEQQF----SGRAVARIFHGIGSPRFPA
QVYGRDRRFWRRHL--------CLSFPALMRLATEEILRWGH------------------
-----------------------------------------------------------

-------MEQLRDVRERVQAWGRAFRRRSGRLPGQENVEA-APEETRALHRDYR-TLKEA
LGQAGGVGPHGSEQ--SLPAAAAEEXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXX-X--XX-------XXXXXXXXX-
X------XXXXXXXXXX--XXXXXXX--X--XXXXXXXXXXXXXXX--XXXXXXXXXXXX
XXXXX---XXXXX-----XXXXXXXXX--XXXXX--------------------------
--X--XXXXXXXXXX-X--XXXXXXXXXXXXXXXXXXXXX-XXXX---------------
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X--XXXXX--XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX------X--------XXX-XXXXXXX
XXXXXXXXXX-XXX--XXXXXXXXXXXX-----------XXXX-XXXXXXXXXXXXXXXX
XXXXXXXXXXXTPAEVLQALEQLGHQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

YPLQERVVMRILSGVSTLLVLPTGAGKSLCYQ
LPALLYFRRSPCLTLVISPLMSLMDNQ-VSGLPPGLKAVCIHSGMTKKERASALQKVR-S
AQVQVLMLSPEALVGAG-----GAALLAQLPLVAFACIDEAHCL----SQWSHNFRPCYL
RVCQV------------LRECVGISCFLGLTATATRSSALD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VARHLGVAEESILRG-PGT
IPANLHLSVSSDRDPEQALVTLLQSDRFCALDSVIVYCNRREDTERVAALLRTCLREAQ-
------APGS

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

RGRAPEAVAEAYHAGMGSRERRRVQRAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAQCHVFLRPQXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX--X-XX-----------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXVPQGTGVLVEFRELAFHLHSPGDLTAQERDQICDFLHGRVQACEREAL
ARLHRTFRAFHSVAFPSCGPCLEQPDEARSGRLKALLSHYFEEELE-------APGGVEA
EEDPEPGQAR-L--QDWEDQIRRDIRHLLSSWPEQRF----SGRAVARIFHGIGSPCYPA
QVYGRDKRFWRKYL--------HLSFHALMRLATEEILLWGC------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 73)

DVRERLQAWERAFRRQRGRRPSQDDVEA-APEETRALYREYR-TLKRT
VGQAGG-EPRSSE---LLPAAVEEAPESHCWGPHLNRAETQSKQPT-PGRSS-QGSVPDY
GQRLKANLKSTL-----QAGPALGCRPWLLGRSSSKT-PTPNP-------PGTRPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQASVSQQLASLDLDWLQRCHSEIPDFLGAPK
ACRPG-LDSEESQ-----LLTPGESAV--LGPGA--------------------------
--GSQDPEASALQEVSISAGSPQPSSSRGKKQRWNKEFWG-SPAQ---------------
VQQQSSQAGHPSEGAGAVALEEDPPGEPVQAQPPQPCSSSSIPRYHRLSTSSQARV--GK
AESTAHLHI-SRLACHDRGNYVRLNMKQKRYVRGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPAGPEPLVP---APQPVPGVPSL-ASTMLPLYSLGPSGQL
SASGPEPLLRETPAEVFQALEQLGHQASVPGQERPVLSQAC---RTTLTTCGAGKSLCYQ
PPALLLLGAAPALTLGHLSLAALMDDQVLSGLPPCLK---------RKQRESVLQKPR--
--YTVLMLTPEALVA----GAGGLPQPTQAA---------SSCF----CLGPINFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRTAGDVAQHLAVDEEPGLHG-PAP
VPANLHLSVSMDRDTDQ

PF00271 // ENSGT00550000074520_1_Domain_3 (858, 986)

ALLTLLQGERFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRAPKTMAEAYHAGMCGRERQRVQQAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACTCTCTRPSPEQEGAMGGER-----------LVPKYPPEEAEQLGVHQAA
PGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPCHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAACLAQRLLEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFTELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCGPCLEQQDDERSTRLKDLLGCYFEEVEEEA----QGPGGMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLFLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAR------------------
-----------------------------------------------------------

-------MERY

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 86)

QEVRTLLKTWEKAFFQEHKRKPNKSDVES-APEETKELYREYR-TLRKS
QESVGLSQPSNSGQ--QDPAVEQQT

ENSGT00550000074520_1_Linker_0_1 (86, 491)

PELDFWGAHLNRNMTKPPLPTQT--AILQVPSQCY
GKKLKSNLKAAL-----QVGPSSGRIPRLPCRQQPKTCPSPKSHLSVPFAPPEVIPSSCE
GDVVMLKPSIPTWSCGPKFIPQLGKLKQLQHTLGQRLSSLDPGWLQRCQDEAKEKPERLE
HSSSL-SS-----------------------------------------LSETLTTKPVF
GSLPEKEDAPSMSEVRTLQRNL------TQKRQRDESQDR-TLKHQKIGTKKKKLRSESA
PESNGEHTRESGRVAALEIPKEDLLGEMVVERMAKTVTGAKAPRYCSQVKL--GRQTSNH
SDHFTELWVFFRTFSKANGNFVRLNLKKKCYAKGFVLRGKHLRKQIWKKKWQMKGEQFGG
GWSRG-RGKE

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 506)

SCFRCGGAGHWASQC

ENSGT00550000074520_1_Linker_1_2 (506, 630)

PGR--------------------------------
-------------ESKKWSRQSQPEEPVP---PKGPECKAPEL-PSAVEPLYGLGPSGQV
A---------ETPLEVFETLTRFGYHTFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 817)

PGQEAAIMRILSGLSTLVVLPTGMGKSLCYQ
LPALLYAQRSCCITLVVSPLLSLMDDQ-VSGLPPGLKAVCVHSNMTRKQRETAMEKVM-T
GKVQVLLLSPEAVVG--AGGFSCLPPAARLPPVAFACIDEAHCL----SQWSHNFRPCYL
RLCKV------------LRERLGVRCFLGLTATATC

ENSGT00550000074520_1_Linker_2_3 (817, 920)

ATARDVGEHLGIPEEAIFGTHLAA
IPPNLHLSVSLDRDKDQALVSLLQGERFRDLSSIIVYCNRRDETVRVAALIRTCLQDFP-
------VPF-AGRLPEAVA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

EAYHAGLSASERRRVQRAFMQGRLRVVVATVAFGMGLDRPD
VRAVLHHGLPGSIESYVQEIGRAGRDGLPAHCHLFLQPQGEDLRELRRHIYADTVDYLTL
KKLVQRLFPPCTCSKQLQQPQMQEVPSS-------------GGEGVQEAGP--QEESEVP
ANVLRICPGHERAFSVQQMVETLDMREEAIETLLCYLELHPRSWLKLLAPIFAICHLKCY
GGPPQLQALA--KRCPAVAVGLAQQQSAKD--KGRSSLDFNVVELADSMGWEAALVRRTL
NQLQWEVTPGKGAPRRTGVLVEFRDLSFHMRSPGL-TAFEQDEICDFLHQRIQAREKEAL
AQLRATFQAFQRVAFPNCGPCMEHVDEERSDQLKALLTRYFEEGTAALFE---DQFREES
EQNHDFGQAR-L--QDWESSICSDIRHLLSIRQEEKF----SGRALARIFHGIGSPCYPA
EVYGKDRRFWRKYL--------HVSFPSLLRLATREILAWK-------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------EPPPKPGQFQQLQASLSLRLCSLDPGWLQRCQNGALDFLPASD
PCK-----AEESQ-----PVTAGELPV--LVSST-----CSKA-----------------
--SSQDPYGPVPQAAQTNAGSFQLCNHRSKKQKWTKEKGS-SPMQ---------------
AQQDYSQARLLSEGAGATAL-KDPTRGAVQVQTPQLYSGTS----------SPAEA--GK
AESTPHLHTSPRTAIRDKGNYVRLNMKQRRYVRGGALRGRLLRKQVWKQKWQKKREHFGG
GRPRA-IVEKSHFQSEQFGYWKSQCPQLGST--P------Q-KEGGDDKDDVQSSPTLKE
VTQRIDAACCYLPG--KDPEPTGPELQ------------APNT-VPSVLPLYPLGPSGQV
A---------ETPAEVFQALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERTIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-LSHLSPSLKAACLHSGMTRKQRDSVLQKVQ-A
AQVHVLMLSPEALVRAGSGGPGGLLQAARLPPVAFACIDEAHCL----STWSHNFRPCYL
RICKV------------LRERMGVHCFLGLTATATHS

ENSGT00550000074520_1_Linker_2_3 (818, 872)

TARDVAHHLGITEELSPRK-GSV
IPANLHLSVSMDRNPDQALVTLLQGDRFRSL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSVIVYCNRREDTLRVAALLRTCLPTVQ-
------DPKARGRVPRAVAEAYHAGMCSQERQRVQQAFMKGQLRVVVATVAFGMGLDRLD
VRAVLHLGLPPSFENYIQGVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVYADGADFLTM
KKLMQCVFPPCTCT--RQE----G-------------------VEPPPQEAKQHGGCPAA
FGQGRACRGHERALPIQPIVQALDMPEEAIETLLCYLELHPQHCLELLPPTYTHCRLYCP
GGTD---------QCPPIAACCARWPPKNTRQ-GSCSMEFNVVELVDSMGWELPPVQRAL
YQLQWDQEPRTGVLRSTGVLVEFGELAFHLRSPGDLTAEERDQVCDFLYSCVQTRERKAL
AHLRHMFQAFHSVAFPSCGPCLEQHDKERSAQLKALLSQYFEEEEEEE---EEEEGDVKN
KQSPEPGQAQ-L--QDWEDQVRHDIRQLLSLWPEERF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLNFHALMRLATEELLLAGP------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 109)

ASVRARLQEWERAFARLHGRRPAREDVEA-APEDTRALYREYR-NLKHA
ARQAGD-GHRSLEQ-S-LAETAEEAQEPSCWGPHLNRAATQNTQPT-PRQGP-LGSVQDY
GKRLKANLESNPKTAKLQTRPALSRKCQPRKRALSTV-PTPRP-------PGPR---TC-
PD-----ETNDVLPRVAEPQPRLGHLQQLQASLSLRLSSLDPGWLERCQDRVSDLLEVPS
ACGLD-LDGKESQ-----PQISGKVNV--LDPGT-----RSEG-----------------
--SSQSPGGLATQP-----QSPKPSNKTDRKWTRNE-SSE-DRAQ---------------
A-QDSGQAGLLSEGARASAHEKDPPGEAA--SAPRPHNSSK-----------RART--ET
AKDK--AHASTRPAFLDRGNYIRLNMKHKCYVRVGASRGRLLRKQVWRQKWRKKAGQFGG
GRAGA-EAQDACFRCGQCGHWASQCPQAGSTRTF------Q-EDSGR--DDKRPVPTLEE
EAQMAGTPSCHLP--GQDTDPDGPKLQVP------------CP-PRPVPPLYPPGPLGHT
T---------ETPAEVFQALQQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQEQAIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPACLKAACLHSGMTKKQREAVLKKVK-A
AQVHVLLVSPEALVGCGAKGPASLPQASELPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHLGVHCLLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 873)

TARDVAQHLGVAEELELSG-LAS
IPANLHLSVSMDRDSDQALVTLLQGDRFCALD

PF00271 // ENSGT00550000074520_1_Domain_3 (873, 986)

SVIIYCTRRKDTERVAALLRTRLSMAT-
------EPRPRGCGPEALAEAYHAGMCSQERRRVQQAFMQGHLRVVVATVAFGMGLDRPD
VRAVLHLGLPPNFESYVQAIGRAGRDGKPAHCHLFLQPQGEDLWELRRHAHADGTDFLAV
KKLVQRVFPSCTCTQ--------------R-----------PMSKPLLEETKERDSQQTH
PALRQACPGHTRAFPVQSTVQALDMTEEAIETLLCYLELHPRRWLKLLSCTYAHCHLRCP
GGSAQLQALA--HRCPPLAACLAKYPPKDTSR-GRSSLDFDMVELADSMGWELASVRRAL
HQLRWDQEPKKGAPRGTGVLVEFSELAFHVHSPGDLTDEEKDQICDFLYSRVQTREHKAL
AHLHQISKAFRSVAFPSCGPCLEQADEDRSNQLKTLLSHYFEEEE---------EEAVKD
EQGPEPGQSE-L--QDWEDHIRRDIHQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QIYGKDQRFWRKYL--------HVNFHAVMRLATEELLR-GR------------------
-----------------------------------------------------------

--------------------------------------------------XXXX-XXXXX
XXXAGG-EPRSSE---LLPAAVEEAPESHCWGPHLNRAETQSKQPT-PGRSS-QGSVPDY
GQRLKANLKSTL-----QAGPALGCRPWLLGRSSSKT-PTPNP-------PGTRPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQASVSQQLASLDLDWLQRCHSEISDFLGAPK
ACRPG-LGSEESQ-----LLTPGESAV--LGPGA--------------------------
--GSQDPEASALQEVSISAGSPQPSSSRGKKQRWNKEFWG-SPAQ---------------
VQQQSSQAGHPSEGAGAVALEEDPPGEPVQAQPPQPCSSSSIPRYHRLSTSSQARV--GK
AESTAHLHI-SRLACHDRGNYVRLNMKQKRYVRGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPAGPELLVP---APQPVPGVPSL-ASTMLPLYSLGPSGQL
A---------EPLLRGWCAL------------------NH

PF00270 // ENSGT00550000074520_1_Domain_2 (641, 817)

GGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLPPTTQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATR

ENSGT00550000074520_1_Linker_2_3 (817, 858)

RTAGDVAQHLAVDEEPGLHG-PAP
VPANLHLSVSMDRDTDQ

PF00271 // ENSGT00550000074520_1_Domain_3 (858, 986)

ALLTLLQGERFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRAPKTMAEAYHAGMCGRERQRVQQAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACTCTCTRPSPEQEGAMGGER-----------LVPKYPPEEAEQLGVHQAA
PGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPCHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAACLAQRLLEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFTELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCGPCLEQQDDERSTRLKDLLGCYFEEVEEEA----QGPGGMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLFLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLQVAR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 86)

DVRERLQAWERAFRRQRGRRPSQDDVEA-APEETRALYREYR-TLKRT
TGQAGG-GLRSSE---SLPAAAEEAPEPRCWGPHLNRAATKSPQST-PGRSR-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRASSKA-STPKP-------PGTGPVPSF-
AE-----KVSDEPPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPK
ACRPD-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSQGPEASAFQEVSIRVGSPQPSSSGGEKRRWNEEPWE-SPAQ---------------
VQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPSSQARA--GK
AEGTAPLHIFPRLARHDRGNYVRLNMKQKHYVRGRALRSRLLRKQAWKQKWRKKGECFGG
GGATV-TTKESCFLNEQFDHWAAQ---CPRPA----------------------------
------------SE--EDTDAVGPEPLVP---SPQPVPEVPSL-DPTVLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYSRRSPCLTLVVSPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKIR-A
AQVHVLMLTPEALV-----GAGGLPPAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVAEEPDLHG-PAP
VPTNLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAW-
------VPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFLAV
KRLVQRVFPACTCTCTRPPSEQEGAVGGER-----------PVPKYPPQEAEQLS-HQAA
PGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCP
GGPAQLQALA--HRCPPLAVCLAQQLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLGRYFEEE--EG----QEPGGMED
AQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SSRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLSFHALVGLATEELLQVAR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 112)

DVRARLLAWERAFRRSHGRRPGQGDVEE-APEDTRALYREYR-ALKKG
LTPAGGVPPRSPEQ--APPAAAEEAREPSCWGPHNRAATPS---ASAHPRTP-RGSAQDY
GKRLKANLRNAL-----QAGPALSRTPRPVQSTPSET-P-QGL-------PGAAAAPTS-
PE-----EPREVPLPPPGPQPRPGRLQQLQLSLSLRLSSLDPGWLQRCHGGAPDSLGIPK
ASGPH-LGGQEQR-----SHEQELQPLASPDPSV-----VSEA-----------------
--SSGDPEAPALPATSVPGGSSQPSHRQSKKRRWSGGPRG-VAGQ---------------
AQQDSSQAGPLPGEAGPVEPKGGPVKEPPSQSL-QDPT----------------------
---------SPRPAPQDRGNYVRLNLKHKRYARGPALQGRRLRRQVWKQKWQKKGECFGG
GQSRA-TGEDSCFCCGQPGHWASQCPQPEPAP--------APREDGGDKADTRALPTLEE
VACRTGTASCEPSGERAQEEPDHPAGTTTAQPRAPTPPEPPRM-HPTVPPLYPPRPSGQV
V---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAVMRILSGLSTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VAGLPPGLKAVCVHSGMTPKQRDKVLQKVQ-M
AKVHVLMLSPEALVGVGAGGPACLPRLGQLPPVAFACIDEAHCL----SQWSHNFRPRYL
RVCKV------------LRERLGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 918)

TARDVGQHLGVAEELGPRGLLAT
IPANLHLSVSMDRDPEQALVALLQGDRFRALDSVIIYCNRREDTERVAALLRTCLRDLQ-
--------GHGGGAREA

PF00271 // ENSGT00550000074520_1_Domain_3 (918, 987)

TAEAYHAGMGSRERRRVQQAFMQGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPASFESYVQAVGRAGRDGQPAHCHLFLRPQGEDLCELRRHAHADTPAG---
------------------------------------------------------------
---EHTCPGWEL-----------------------------RPWAGPL------------
--PTHPFLSE--RRCPPLAACLARQPPL--GT-GSSSVEFDVVELADSMGWELAPVRRAL
RQLQWDGEPG------TGVRVEFRELAFHLRCPGDLTAEERDQVCQLLHGRVQAREREAL
ARLRRVFQAFHSVAFPSCGPCLEHPDMERSARLKALLGRYFEEEE-E------PEEGSGG
GQGLEPGQAS-L--QDWEDQARRDVRLLLSLRPEERF----TGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKYL--------HVSFHALVGLATEEILLWGR------------------
-----------------------------------------------------------

------------------------------------------------------------
--------------------AAEEASEPHCWGPHLNRAATQSPQPT-PGRSC-QGSFRDY
GQRLKANLKGTL-----QAGPALGHRPWPPGRSSSKT-PTPKL-------PGTGPVPTF-
AE-----KVSDVSSQSSGPWPRPGRLQHLWASLSLRLGSLDPGWLQRCHSGVPDFLGAPK
PCRPG-LGSEESQ-----LLTAGESAI--LGPGA--------------------------
--RSQGPEASALQELSIGAGSPQPSSSRGEKRRRNEVPWG-SPTQ---------------
VQQPSSQAGPPLEAAEAIALEEDSPGEPVQAQPPQPCSSRSTPRYHRLSPSSQARA--EK
AEGIAPLHIFPRLAGHDRGNYVRLNMKQKRYVRGRALRGRLLRKQAWKQKWQKKGECSGS
GDGTV-TVKESCFLNGQFDHRAPQ---CLQPA----------------------------
------------SE--EDADPAGPGPLVP---EPEPEPEVPGL-APAVPPLYSPEPSGQV
A---------ETPAEVFHALEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAVMRILSGISTLLVLSTGAGKSLCYQ
LPALLYARRSPCLTLVVSPLLSLMDDQ-VSGLPSCLKAACIHSGMTRKQRESVLKKVQ-A
GQVHVLLLTPEALV-----GAGGLPPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATRR

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAQHLAVAEEPGLRG-PAP
VPANLHLSVSMDRDTDQALLTLLQGGRFRN

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSIIIYCNRREDTERVAALLRTCLHPAQ-
------GPGPKGGAPKTMAEAYHAGMCSRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHAAGTDFWAV
KRLVQRIFPPCT--CARLPPEQEGAGGGET-----------PVAGSPAQEVEQLGGRQAA
PGPRRSCVGHERALPVQPTVQALDMPEEAIETLLCYLELHPQHWLELLATTYSHCHLHCS
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVELVDSMGWELACVRRAL
CQLQWDHEPQTGMWQSTGVRVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVQAQEHQAL
ARLHRTFQAFRSVAFPSCGPCLEQPDEERSTRLKELLSRYFEEVEEEA----QGPGGVGD
THGPEPGQAR-L--QDWEDQVRRDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVFGQDRRFWRKYL--------HLSFHALVRLATEELLQVGR------------------
-----------------------------------------------------------

-------MERLWDVRLRLQAWEQAFRRERARRPGQEDVQA-APEEIRALYRQYR-VLKKA
VRQAGG-P----------QAEAQEDPESSCWGSHLNRSVAGSSRPT-SGQKP-LASGQDY
GKRLKANLQVKV-----RXXXXXXXXXXXXXXXXXXX-XXXXX-------XXXXXXXXX-
XX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPDWLQC-HHGSPGVG----
-VSPG-LE-PECQ-----LLTIGQQSS--VDPIA--------------------------
-----GCEASGALAAHTHADDL----QPGQKRSRNEGPGG-SLAC---------------
VQQEGGQEA-----------EKDTVGGPAGGG----------------SLSCGACV--GQ
TVGTAPLCSSPRTGVQERGNYVRLNMKQRRYVRWA--FGRALLRQARKQKWQKKATGLTG
GRPKA-TSR

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

DSCFRCGQPGHWASHCP

ENSGT00550000074520_1_Linker_1_2 (507, 629)

QPGDRD----------------------------
------------------RE--PPELE-------------SPL-PPPVPPLYPMEPSKQM
A---------ETPAEVYQALEELGYQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQERAIMRILSGVSTLLVLPTGAGKSLCYQ
LPALMFARRSPCLSLVISPLLSLMDDQ-VSGLPRSLKAACLHSGMSRKQRDSVLQKVR-A
AQVHVLMLSPEALVG-----AGAIPLTTQLPPVAFVCIDEAHCL----SQWSHNFRPCYL
HVCKV------------LRERVGVRCFLGLTATATRSTARD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VARHLGVADELGLRE-PVA
VPLNLHLSVSMDREPEQALVTLLQGDRFRVLDSIIVYCPRREDTERLAALLRTCLRD---
------TPEA

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

RGRDPEAIAQAYHAGMLSQERRRVQRAFMQGQLRVVVATMAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLRPQGEDLQELRRHVHAHGTDFLAV
KRLVQRVFASCMCP--QLPLDGEG-----------------PTPSEPPPR-------EAP
ASGTRRCPGHERMLPVQQMVQALDMPEEAIETLLCYLELHSQRWLQLLPATYARCRLHCP
GGPTQLQALA--PRCPPLALCLAQWPPGDRRH-SSSSVELDMVELLDLSGWELASLRRAL
RQLEWDLQSGTGAPQRTGVLVEFEELAFHLCSPGDLSAVELDQVCDFLYSCVQAHERKGL
ARLCHVSQAFRSVAFPSCGPCLERADQERSAQLKALLSHYFEEEQKL---------GLEE
QQGPELGLVS-I--QDWEDQVRRDIRLLLSLRPEERF----SGRAVARIFHGIGSPCYPA
QVFGRDQRFWRRYL--------QLSFHSLMRLATEELIRTGH------------------
-----------------------------------------------------------

-------MDRL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 88)

ASVRARLQQWERAFARLHGRRPAQEDVEA-APEETRALYREYR-NLKQA
VRQAQD-GRRRIPEQSLAAEAAEEARE

ENSGT00550000074520_1_Linker_0_1 (88, 491)

PSCWGPHLNRAATQNTQPM-PRQRP-LSSVQDY
GKRLKANLK----KTKLQTRPTLSPKLQPQKRSLSTV-PTLRP-------PDPG---TC-
PD-----ETNDELPRLPEPQPRLGQLQQLQASLSLRLSSLDPGWLERCQDGFS---EAPS
ACGLD-LDAKESQ-----PQIPGKVNV--PDPGI-----HSEG-----------------
--SSQSSEALALQP-----QSPKSSNNKDRKRKWSE-NSE-DFAQ---------------
A-QDSSQAELLSEGARAAAHEKDPPGEHAQGNASQPRESSN-----------QART--EK
AKGTAQLHSSPRPALLDRGNYVRLNMKQKCYVRVGANRGRLLRKQVWKQKWKKKREQFGG
SGPRA-TVKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQSGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGSTQTF------Q-EEGGR--DDKQPVSALEE
VAQMTGATSCHLS--GEDTEPDGPKLQVP------------CP-PRPMLPLYPPGPLGQV
A---------ESPAEVFQALQQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVVSPLLSLMDDQ-VSDLPLCLKAACLHSGMTKKQRESVLKKVK-A
AQVHVLIVSPEALVGCGA----NFPQATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 873)

TARDVAQHLGITEELELSG-LAT
IPANLHLSVSMDRDSDQALVTLLRGDRFCALD

PF00271 // ENSGT00550000074520_1_Domain_3 (873, 986)

SIIVYCTRRKDTERVAALLRTCLSVVT-
------HPRPKGCGPEAVAEAYHAGMCGQERRRVQQAFMQGHLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFLQPQGEDLWELRRHAHADGTDFWAV
KRLVQRVFPPCMCAS--------------R-----------PVTNSLLGEAREHNGQPAT
PGVGPACPGHKRVLPVQSTVQALDMTEEAIETLLCYLELHPRRWLQLLPCTYAHCHLRCP
GGCAQLQALA--HRCPPLAAGWAKWPPKETRQ-GSSSLEFDMVELADSMGWELASVRRAL
HQLQSDQQPKRGAPRGTGVHVEFSELAFSLLSPGDLTDEEKDQICDFLYSRVQARERKAL
AHLRHISKAFRSVAFPSCGPCLEQSDEERSNRLKTLLSHYFEEE-----------ESVAD
EQGPEPGQNE-L--QDWEDHIRRDVRQLLSVRPEERF----SGRAVARIFHGIASPCYPA
QVYGQDRRFWRKYL--------HLNFHTLMRLATEELLLIGR------------------
-----------------------------------------------------------

-------MEPLW

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 61)

NLRAHLQAWERAFARQHGRRPGQEDVEA-APEETRALYRKYR-ALKQA

ENSGT00550000074520_1_Linker_0_1 (61, 491)

VGRRSG-GPCSHNQ--LLSASAQEAPNPTCWGSHLNRAATQSPHRT-PVLSP-QRSAQDY
GKRLKANLKGTL-----QDDPALGHRCQPPGRRLSKK-PTPKP-------LSPGTPSTS-
PE-----ELSDALTKPSEPQPRPGRLQQLRASLNLRLSSLDPGWLQRCHNGALDCLQASE
PSS-----TKESQ-----PMTPGELSV--LVTNT-----YSEA-----------------
--TSQDPVAPVPQAAQTSAGRPQFNSHRGKKQKWTEENGS-IPVQ---------------
AQRDSNQATLQSEGAGATVL-EDPTGGAVQVQTPQLCPGTS----------RSLKA--EK
AESIPHPHTCPQTVIQDKGNYVRLNMKQKRYARVGALRGRLLRKQAWKQKWQKKKEYLRG
GGPRA-TTEK

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFQCGQFGHWKSQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QLGPMQAL------Q-KEGDKDKDDMQSFPTLEE
VTQRIDTAC---PK--QDTESAEPDLQ------------APNT-APSVLPLYPPGPLGQV
A---------ETPAEVFRALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERTIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVISPLLSLMDDQ-LSHLPACLKAACLHSGMTRKQRQSVLQKVQ-A
AQVHVLMLSPEALVGAGSGSPVSLPQASQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVSCFLGLTATATRN

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAHHLGVAEEPSPRE-APV
IPANLYLSVSRDRDPDQALVTLLQGDRFRS

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIVYCNRREDTQRIAALLRTCLCAVQ-
------DPKLRGRGPAAVAEAYHAGLCNRERQRVQQAFMKGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQGVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADGADFLAM
KKLMQCVFPPCTCI--Q------------R-----------PTAESPPLEAKQHGGYPAA
FRQGRACLGHERALPVQPTVQALDMPEEAIETLLCYLELHPQHWLELLPATYAHCRLYCP
GGTSQLQALA--SRCPPVAACWAQWPPENTRH-GSCSLEFNVVELVDSMGWELPSVRRAL
HQLQWDREPKTGVLQSTGVLVEFGELAFHLHSPGDLTAQERDQVCDFLYSCVQTRERKAL
AHLRRMFQAFHSVALPSCGPCLEQPDEERSAQLKTLLSCYFEEEEE-----EEKEGHVKD
KQSTEPGQVQ-L--QDWEDQVRHDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGRDQRFWRKYL--------HLNFHALMRLATEELLLAGP------------------
-----------------------------------------------------------

-------MGRL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 88)

ASVRARLQEWERAFARRHGRRPAREDVEA-APEETRALYREYR-NLKHA
VLQAGD-GHRILEQ-S-LPETAEEAQE

ENSGT00550000074520_1_Linker_0_1 (88, 491)

PSCWGPHLNRAATQNTQPI-PRQGP-SSSVQDY
GKRLKANLENNPKT----TRPNLSRKRQPQKRTSPTV-PTPRP-------PGPR---TC-
PD-----ETNDVLPRLPEPQPRLGQLQQLQASLSLRLSSLDPGWLERCHNRVSDLLEVPS
ACRLD-LDGKGLQ-----PQMSGEVNV--LDPGT-----HSEG-----------------
--SSQSPGALAIQP-----QSPKSSNKKDRKQNWSE-SSE-DFAQ---------------
A-QDSSQEGLLCKGAGATAHEKDHPGEPALVSASRPHNSSK-----------KART--EK
AEGKAHAHTTTRPAFLDRGNYIRLNMKQKCYVRVGANRGRLLRKQVWKQKWKKKGEQFGG
SRPRA-TVQD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFQCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGSTMTF------Q-EEGGG--DDKQPISTLEE
DTQMASTPSCHLST-GEDTDPDGPKLQVP------------CP-PRPVLPFYPPGPSGHI
A---------ETPAEVFQALQQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQEHAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPACLKAARLHSGMTKKQREAVLKKVRRA
AQVHVLLVSPEALVGCWAKGPASLPQATQLPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVHCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 873)

TARDVAQHLGIAEELELSG-LAT
IPANLHLSVSVDRDSDQALVTLLQGDRFCTLD

PF00271 // ENSGT00550000074520_1_Domain_3 (873, 986)

SIIIYCTRRKDTERVAALLRTCLSVVR-
------EPRHGGCGPEAIAEAYHAGMCSQERRRVQQAFMQGHLRVVVATVAFGMGLDRPD
VRAVLHMGLPPNFESYVQAIGRAGRDGKPAHCHLFLQPQGEDLWELRRHAHADGIDFLAV
KKLVQRVFPSCTCTR--------------R-----------PMSKPMLEEAKEHNSQQIH
PVLGQACLGHKRAFPVQSTVQALDMTEEAIETLLCYLELHPRRWLELLPCTYAHCHLHCP
GGSAQLQALA--HRCPPLAACLAKYPPKDTSR-GSSSLDFDMVELADSMGWDLSSVRRAL
YQLQWDQEPKKGAPRGTRVLVEFSELAFHLHSPGDLTDEEKDQICDFLYSCVQAREHKAL
AHLHQISMAFRSVAFPSCGPCLEQADEERSNQLKTLLSHYFEEEE---------EEAVKD
EQSPEPGQTE-L--QDWEDHIRRDIRQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QVYGQDRRFWRKYL--------HMNFHALMRLATEELLLRGR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 60)

DVRERLQAWERAFRQQHGRRPSQDDVKA-APEETRALYREYRTLKRTV
RQSAGG-GGPCSRE--SLPAAAEEAPEPRCWGPHLNRAATQSPQPA-PGRSC-QGSFRDY
GQRLKANLKGTL-----QASPALGHRPWPPGRSSSET-PTPKL-------PGTGPVPTF-
AE-----KVGDMPPQPSGPWPRPGRLQHLRASLSLRLGSLDPGWLQRCHSGVPDFLGAPK
PCRPG-PGSEESQ-----LLTAGESAV--LGPGA--------------------------
--GSQGPEAS---EVSIGVGSSQPSSSRREKRRRNEVPWG-SPTQ---------------
VQHQSSQAGPLSEAAEAIALEEDSPGEPAPAQPPQPCGSQSTPRYHRLSPSSQARA--EK
AEGIAHLHIFPRLAGHDRGNYVRLNMKQKRYVRGRALRGRLLRKQAWKQKWRKKSECFGG
GDATV-TIKESCFLNEQFDHRAAQ---CPQPA----------------------------
------------NE--EDTDPAGPEPLVP---APQPVPEVPGL-APTVLPLYSLGPSGQV
A---------ETPAEVFHALEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLSPCLKAACIHSGMTRKQRESVLQKVQ-A
GQVHVLLLTPEALV-----GTGAFPSATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 858)

ASDVSQHLAVAEEPGLHG-PAP
VPANLHLSVSMDRDTDQ

PF00271 // ENSGT00550000074520_1_Domain_3 (858, 986)

ALLTLLQGERFRNLDSIIIYCNRREDTERVAALLRTCLRPAQ-
------GPGPKGCAPKTTAEAYHAGMCSRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPEGEDLRELRRHVHANGMDFWAV
KRLVQRVFPSCT--CARLPPEQEGARGGEM-----------PVAGSPPQEAEQLAGCQAA
LGPRRACVGHERALPVQPTVQALDMPEEAIETLLCYLELHPQHWLELLATTYTHCHLHCS
GGPAQLQALA--HRCPPLAVCLAQQLPEDPGQ-GSSSVEFDMVKLVDSMGWELACVRRAL
CQLQWDHEPRTGMWQSTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVQAREHQAL
AHLHRAFQAFHSVAFPSCGPCLEQQDDERSTRLKDLLSRYFEEVEEEA----HGPGGMGD
TQEPEPGQAR-L--QDWEDQVRRDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVFGQDRRFWRKYL--------HLSFHTLARLATEELLQVGR------------------
-----------------------------------------------------------

-------MERLRDVRGRLQAWEQKFRRQRGRRPAKSDEGG-DPEAWVSG---NP-ASSGH
-----ILGPGGG-S--DARRVSPQMQEPSCWGPHLSRAATRRPHAAGYAPGS-AGAVADY
GARLKANLRATR-----QAGPALGGIPRPPRRLSSEM-PFPGP-------PDAGAAPVS-
AE------VSEELLQLPGPQPRPGRLQQLQASLSLRLSSLDPGWLERCHSAASDCLRASA
ACQPS-LGVEESQ-----PLTSGVPSV--LGASP-----GPE------------------
--------GRALQRAAVGAGSPEAGNSQGKKRRRTKETGG-GPAQ---------------
AQQDSGQAGPPPEEAGAVGPAEDCPGEPLRVQPASGPTAT-----------R---Y--HS
ALGTTRSYILSSSAVRDQGNYVRLNLKQKRYVRGPAQRGRLLRKQMWKQKWRKKGEHFGG
SQARA-TADD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQLGHWSSQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPKPT--------WGPQTSSEKEEEVQPQLTPEE
GPRRTGTTSCRLPVSEEDTEPAGPERLVT---TERPVLQAPCP-PPTVPPLYPPGPSGQV
A---------ETPAEVFQALEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PRQEQVVMRVLSGMSTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSSLPPCLKGVCIHSGMSQKQRESALQKVH-A
AQVQLLVLSPETLVGAGAGMPGHLP---QLPPVAFACIDEAHCI----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATRSTARDVARHLGVAEELVLRGP-AT
VPSNLHLSVSRDRDPDQALVTLLQSDRFRALSSVIVYCHRRGDTERVAALLRTCLREAW-
------DLRPGGEVSRTVPC-------TRPPTP---------------------------
---------------------PPPAPHSPPHSSVTPFLQSQDLQELRRHVHADATDFLTM
KKLVQRAFPPCTCTHAPRPSEQEGARSQEQ-----------PVA-----PSPTEA-EQPN
SKGTARCPGHTRALPMQALVEALDMPEEAIETLLCYLELHPQRWLQLLPPTYAQCRLHCP
GGPTQLQALA--RRCPLLAVCLAQQPADTTDG-GSSSVEFDVFNLADSLGWKLGRVRQAL
RQLQWDPKPRTGAHGGTGVQVEFGELAFCVHSPGDLTAHERDQICDFLYGHIQAREQEAL
ARLRRTFQAFLSVAFPSCGPCLEQPDEERSTRLKALLSGYFEEEEEE------GPGGSED
EQGLEPGQEK-I--QDWEDQVRQDVHRLLSSWPDQQF----SGRAVARIFHGIGSPRYPA
QVYGRDRRFWRRFL--------HLSFQALMRIATEEILRCGP------------------
-----------------------------------------------------------

-------MERLRDVRERLQAWESTFRRRRGRRPGQEDVAA-APEDTRALYREYR-ALKEA
LKEAEGVGPRGPKQ--SLSVQAEEVPEPSCWGPHLNRAATHSRHPPLSGPSR-PGSVRDY
GERLKANLKGTL-----QAGPALSRIPRTPRRPSSEM-PTPRP-------PGAGAALIS-
PE-----EVSEVPLQPAGPQLRPGCLQQLQASLSLRLGSLDPGWLERCHNGAPDFLGASK
ACQPN-LGVEQSQ-----SLTSCVPSV--PGPST-----SPE------------------
--------AQALQTAGVSAGSPQPGDSQGKRWTRNREPEG-SPAQ---------------
AQQDSGQIGPLPEEAGTAEHAEDPSGKPLWAQRPSGATAS--------------------
-----------RVAVRNEGNYVRLNMKQKRYVRGPALRGRLLRKQMWKQKWQKKEERFVG
GRPRA-TLKN

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQLGHWSSQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPEHTPA-------PQKKGGENEDDTQTLLTLEE
VVQRTGSASCRLPVSEKDPEPAGPELLVT---VEQPVPRVPCL-PPTVPPLYPPGPSGQV
A---------ETPAEVFQALEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 817)

PGQEHAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKERDSALKKVQ-A
AQVHVLMLSPEALVGAAAGTPGSLP---QLPPVAFACVDEAHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATH

ENSGT00550000074520_1_Linker_2_3 (817, 869)

STSRDMAQHLGVAEEHVLRGP-VT
IPTNLYLSVSTDRNPDQALVTLLQSDRF

PF00271 // ENSGT00550000074520_1_Domain_3 (869, 986)

RDLNSVIVYCNRREDTERIAALLRTCLC----
------------QAPEAVAEAYHAGMCARERRRVQQAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGQDLQELRRHVHAEASDFLAV
KKLVQCSFPPCTCTHARQPPEQEGAKSQER-----------PVT-----VSPSEA-EQAS
NKGLAQCLGHERALPVQPLVQALDMPEEAIETLLCYLELHPRRWLELLAPTYAYCHLRCP
GGLPQLQALA--RRCPPLAVWLAQQPQENIGE-GSYSVEFDVVKLADSMGWKLAPAKQAL
RQLQWYPEPRTGALRDTGVLVEFRELAFCLHSPGDLTAHEKDQICDFLYERVQTREQEAL
ARLRRTFQAFHSVAFPSCGPCLEQPDEEHSARLKVLLSGYFEE---E------GPGGMED
EQGPEPGQAR-I--QDWEDQIRQDIRHLLSSWPDQQF----SGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKHL--------HLSFHALMRLATEEILLWGH------------------
-----------------------------------------------------------

-------MDRLW

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 66)

NLRARLQEWERKFTRQHGRRPDQEDVEA-APEETRALYRKYR-ALKQS
VGQRIG-GPHSHNQ--SLSAAAQEAPEPGCWGSHLNRSATQSPQPT-PVLSP-QGSAQNY
GKRLKANLKATL-----QAEPTLGCRRQPPGRFLSKK-PTLKT-------LSPGIPPTS-
PE-----ELSDSLTKPSEPPPKPGQFQQLQASLSLRLCSLDPGWLQRCQNGALDFLPASD
PCK-----AEESQ-----PVTAGELPV--LVSST-----CSKA-----------------
--SSQDPYGPVPQAAQTNAGSFQLCNHRSKKQKWTKEKGS-SPMQ---------------
AQQDYSQARLLSEGAGATAL-KDPTRGAVQVQTPQLYSGTS----------SPAEA--GK
AESTPHLHTSPRTAIRDKGNYVRLNMKQRRYVRGGALRGRLLRKQVWKQKWQKKREHFGG
GRPRA-IVEKSHFQSEQFGYWKSQCPQLGST--P------Q-KEGGDDKDDVQSSPTLKE
VTQRIDAACCYLPG--KDPEPTGPELQ------------APNT-VPSVLPLYPLGPSGQV
A---------ETPAEVFQALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERTIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-LSHLSPSLKAACLHSGMTRKQRDSVLQKVQ-A
AQVHVLMLSPEALVRAGSGGPGGLLQAARLPPVAFACIDEAHCL----STWSHNFRPCYL
RICKV------------LRERMGVHCFLGLTATATHS

ENSGT00550000074520_1_Linker_2_3 (818, 872)

TARDVAHHLGITEELSPRK-GSV
IPANLHLSVSMDRNPDQALVTLLQGDRFRSL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSVIVYCNRREDTLRVAALLRTCLPTVQ-
------DPKARGRVPRAVAEAYHAGMCSQERQRVQQAFMKGQLRVVVATVAFGMGLDRLD
VRAVLHLGLPPSFENYIQGVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVYADGADFLTM
KKLMQCVFPPCTCT--RQE----GGNSGVR-----------SAVEPPPQEAKQHGGCPAA
FGQGRACRGHERALPIQPIVQALDMPEEAIETLLCYLELHPQHCLELLPPTYTHCRLYCP
GGTDQLQALA--QRCPPIAACCARWPPKNTRQ-GSCSMEFNVVELVDSMGWELPPVQQAL
YQLQWDQEPRTGVLRSTGVLVEFGELAFHLRSPGDLTAEERDQVCDFLYSCVQTRERKAL
AHLRHMFQAFHSVAFPSCGPCLEQHDKERSAQLKALLSQYFEEEEEEE---EEEEGDVKN
KQSPEPGQAQ-L--QDWEDQVRHDIRQLLSLWPEERF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLNFHALMRLATEELLLAGP------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 69)

DIRERLQAWERAFRRQRGRRPGQEDVEA-APEETRALYREYR-ALKET
LGQAGDVR

ENSGT00550000074520_1_Linker_0_1 (69, 491)

PNSLGR--SLSAAAEETLEPSCWGPHLNRAATQTPHST-SRLIP-QGSVQDY
GKRLKANLKDSL-----QTGPALGRVPRLERTPFSKK-SSPGS-------PGTAAALIS-
PE-----EVGKVP-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---SQLPRTQLRPAIQDRGNYVRLNMKQKRYVRGLAPRSRLLRRQVWKQKWQKKGESFGG
GQPRA-TAKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQLGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPEP--AP------Q-KEGGKDEDDTGTLPMLEE
VPQRTGTTCCQLPG-EEDTEPAGPELSVP---MQSSMPRAPCPPPPPVPPLYPLGPSGQV
A---------DTPAEVFQALEQLGHQAFN

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 816)

PGQEHVVMRILSGMSTLLVLPTGGGKSLCYQ
LPALLYSRRSPCLTLVISPLMSLMDDQ-VSGLPPGLKAACIHSGMSKKQRNSALQKAR-S
AQVQVLMLSPEALAGAGA---AGLAFLTQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERVGVSCFLGLTATAT

ENSGT00550000074520_1_Linker_2_3 (816, 872)

RSTALDVAQHLGVAEESVLRG-QGT
IPANLHLSVSMDRDPDQALVTLLQSDRFCAL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSIIIYCNRREDTERVAALLRTCLRW---
-------------APEAVAEAYHAGMCSRERRRVQRAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLRPQAEDLWELRRHVHADAIDFLAV
KKLVQHVFPACGHAQ--QPLVPEPGESQES-----------SAATVP-WDA-----DHPH
VELTARCPGHERALPVQPMVQALDVPEEAIETLLCYLELHPQRWLKLLEPTYARCHLRCP
GGPTQLQALA--RRCPPLAACLAQQSPENT-----ASVEFDVVELADSMGWELAPVRRAL
RQLQWDPEPRTGLPRGTGVLVDFKVLAFHLRSPGDLTAQEKDQICDFLHGRVQAREREAL
ARLHHTYWAFHSVAFPSCGPCLEQPDEERSGRLKALLRRYFEEEEA-------GPEG-MD
QQGPEPGQAT-L--QDWEAQIRRDIRHLLSSWPEQQF----SGRAVARVFHGIGEDLG--
------GTAWRKAGAGSQSPQGHISVHRRESPLSSPGVRAGPALLEKIPAPELPRPDAPG
HRGDPAVGPLSGLLGGPCQHSRDEASAARTLCSPSGQSLLPGRGGKEALKQNKRCSRLF

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 64)

DVRERLQAWERAFRRERGRRPSQDDVEA-APQETRALYREYR-TLKRT
VGQAGG-GPRSSEL---LPVAVEEAPESHCWGPHLNRAATHSPQHT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPAPGRRPWPLGRSSSKT-PTPNP-------PGTRPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQACLSQQLASLDLDWLQRCHSEIPDFLGAPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSPDPEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPAQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPPQPCSSLSTPRYHRFSTSSQARA--GK
AEGTAHLHI-SRLARHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQSV----------------------------
------------SE--EDTDPAGPEPLVP---APQPVPGVPGL-ASTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLSPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVNEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRAPKTTAEAYHAGMCGRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGTMGGEK-----------PVPKYSSQEAEQLGVHQAA
LGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPRHWLELLATTYIHCRLSCP
GGSAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ACLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPKEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAY------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 122)

ATVRARLQEWERAFARLHGRRPAKGDVEA-APEETRALYREYR-NLKQA
VRQADD-RHRVLEQ--SLAEAAEEAQEPSCWGPHLSRAATQNTQSM-PKQSL-LSSVQDY
G

ENSGT00550000074520_1_Linker_0_1 (122, 491)

KRLKANLKNTT-----QTGPTQSRKLQLQKRSLSTV-PAPRP-------PGSKTESPC-
PD-----EADDALPRVPEPRPRLGQLQQLRSSLSRRLTSLDPGWLERCHNRVSDLLEVPG
ACGLD-LSAEESQ-----PQMSGKVNI--ADPDI-----QSEV-----------------
--SVQSPEAIAQQPAQVLSQSPKSINSKGRKRKWNE-KGE-DFAQ---------------
D-QPSSGAGPLSEGARATVHGQDPPGEPTQVNVPQPCNSSN-----------QART--EK
AKGTTHLHASPRPASLDRGNYIRLNMKNKRFVRVGANRGRLLRKQVWKQKWKKKQAAFGG
SGPRA-TDKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGPTLTV------Q-EEGDR--DDKQPISTLEE
VAQRTGTASCHHS--GEETQPAAPELQVP------------HC-PTPMSPLYPPGPLGQV
A---------ETPAEVFQALERLGYRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPSCLKAACLHSGMTKKQRESVLKKVR-A
AQVHVLIVSPEALVGCGARGPGSLPQAAQLPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAQHLGIAGEFELSG-SAN
IPANLHLSVSMDRDSDQALVTLLQGDRFRT

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIIYCTRRKDTERVAALLRTCLSMVG-
------DSRPRGCGPEAIAEAYHAGMSSQERRRVQQAFMRGHLRMVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFMHPQGEDLWELRRHAHADSTDFLAV
KRLVQRVFPPCTCSQ--------------R-----------PVSKSSPEEVKEHSGQQTY
PVLGQACLGHERALPVQSTVQALDMTEEAIETLLCYLELHPRHWLELLPWTYAQCHLHCL
GGSAQLQALA--HRCPPLAACQAKWPPKDTSQ-GRSSLEFGVVELADSMGWKLASVRQAL
HQLKWDPEPKKGAAQGTGVLVKFSELAFHLHSRGDLTDEEKDQICDFLYNRVQAREHKAL
AHLHQMSKAFRSVAFPSCGPCLEQSNEEHSNQVKTLVSYYFEEEE--E-----EEETMTD
TQGPKPGQTQ-L--QDWEDQIRRDVRQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QVYGLDRRFWRKYL--------HLDFHALMHLATEELLLRGR------------------
-----------------------------------------------------------

-------PDRSLPLRSNFLRWAACGLRARKRRSSGSRAQKANSRLSRGLCRVLQGTQGSQ
TGRAGE-GPYRRE---G--QGSGGAPEPRCWGPHLNRAATKSPQPT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRASSKA-STPKP-------PGTGPVPFF-
AE-----KVSDEPPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPK
ACRPD-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSQGPEASALQEVSIRAGSPQPSSSGGEKRRWNEEPWE-SPAQ---------------
VQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPSSQARA--GK
AEGTAPLHIFPRLARHDRGNYVRLNMKRKHYVRGQALRSRLLRKQAWKQKWRKKGECFGG
GGATV-TTKESCFLNEQFDHWAAQ---CPLPA----------------------------
------------SE--KDTDPVGPEPLVP---SPQPVSEVPSL-DPTVLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYSRRSPCLTLVVSPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKIR-A
AQVHVLMLTPEALV-----GAGGLPPAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 859)

ASDVAQHLAVAEEPDLHG-PAP
VPTNLHLSVSMDRDTDQA

PF00271 // ENSGT00550000074520_1_Domain_3 (859, 986)

LLMLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHADW-
------VPGSGGHAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATMAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLRPQGEDLRELRRHVHADSTDFLAV
KRLVQRVFPACTCTCTRPPSEQEGAVGGER-----------PVPKYPPQEAEQLG-HQAA
PGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVKFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLGRYFEEE--EG----QEPGGMED
AQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SSRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLSFHALVGLATEELLRVAR------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MKQKRYMRGRALGGRLLRKQAWKQKWQKKRECFGG
GGPRA-SVKESCFPCEQFGHWASQ---CPQPA----------------------------
------------SE--EDTEPAEPELLVP---ASQRVPEVPHL-APTVLPLYPPGPLGQV
A---------EAPAEVFQALEQLGYQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCITLVISPLLSLMEDQ-VSGLPSCLKVACIHSGMTRKQRDSVVQKVQ-T
AQVHVLMLSPEALVGTGVWSPANLPQAAQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKM------------LRERMGVRCFLGLTATATRST

ENSGT00550000074520_1_Linker_2_3 (819, 871)

VRVIAQHLGVAEEVGMRG-PAP
IPANLHLSVSMDRDTDQALVTLLQGDRFRT

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIVYCNRRVDTERVAALLRTCLCATQ-
------GQEPGGHAPKTIAEAYHAGMCSRERQRVQLAFMQGQLRVVVATVAFGMGLNRSD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHIHACGTDFLTV
KKLVQRVFPPCTC--SLPALEEEGAVGRER-----------PVAKSSPQEAKQHNSHQAA
SVPRRACLGHELALPVQPTVQALDMPEEAIETLLCYLELHPRHWLELLATTCARCHLHCP
GGLAQLQTLA--QRCPPLAVYLTRKPPEDIQQ-GSSSVEFDMVKLGDSMGWELASVRKAL
CWLQWNQEPRTGVSRVPGVLVEFGELAFHLRSPGDLTAKERDQICDFLYGRIQTRERQAL
AHLCRTFQTFHSVAFPSCGPCLEQPNEERSTRLKALISDYFEEE--EA----QEPRGLED
EQAPEPGQAR-L--QDWEDQIRRDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVFGQDRRFWRKYL--------HLSFHALMHLATEELLLRGH------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 122)

ATVRARLQEWERAFARLHGRRPAKGDVEA-APEETRALYREYR-NLKQA
VRQADD-KHRVLEQ--SLAEAAEEAQEPSCWGPHLSRAATQNTQSM-PKQSL-LSSVQDY
G

ENSGT00550000074520_1_Linker_0_1 (122, 491)

KRLKANLKNTT-----QTGPTQSRKLQPQKRSLSTV-PAPRP-------PGSKTESPC-
PD-----EADDALPRVPEPRPRLGQLQQLRSSLSRRLTSLDPGWLERCHNRVSDLLEVPG
ACGLD-LSAEESQ-----PQMSGKVNI--ADPDI-----QSEV-----------------
--SAQSPEAIAQQPAQVLSQSPKSINSKGRKRKWNE-KGE-DFAQ---------------
D-QPSGRAGPLSEGAGATAHGQDPPGEPTQVNVPQPCNSSN-----------QART--EK
AKGATHLHDSPRPASLDRGNYIRLNMKNKCFVRVGANRGRLLRKQVWKQKWKKKQAAFGG
SGPRA-TDKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGPTLTV------Q-EEGDR--DDKQPISTLEE
VAQRTGTASCHHS--GEETQPAAPELQVP------------HC-PTPMSPLYPPGPLGQV
A---------ETPAEVFQALERLGYQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 817)

PGQERAIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPSCLKAACLHSGMTKKQRESVLKKVR-A
AQVHVLIVSPEALVGCGARGPGSLPEAAQLPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVCCFLGLTATATR

ENSGT00550000074520_1_Linker_2_3 (817, 871)

STARDVAQHLGIAGEFELSG-SAN
IPANLHLSVSMDRDSDQALVTLLQGDRFRT

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 987)

LDSVIIYCTRRKDTERVAALLRTCLSMVG-
------DSRPRGCGPEAIAEAYHAGMSSQERRRVQQAFMRGHLRMVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFMHPQGEDLWELRRHAHADSTDFLAV
KRLVQRVFPPCTCSQ--------------R-----------PVPKSSPEEVKEHSGQQTY
PVLGQACLGHERALPVQSTVQALDMTEEAIETLLCYLELHPRHWLELLPWTYAQCHLHCP
GGSAQLQALA--HRCPPLAACQAKWPPKDTSQ-GRSSLEFGVVELADSMGWKLASVRQAL
HQLKWDPEPKKGAAQGTGVLVKFSELAFHLHSRGDLTDEEKDQICDFLYNRVQAREHKAL
AHLHQMSKAFRSVAFPSCGPCLEQSNEEHSNQVKTLVSYYFEEEE--E-----EEETMTD
TQGPKPGQTQ-L--QDWEDQIRRDIRQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QVYGLDRRFWRKYL--------HLDFHALMHLATEELLLRGR------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MSGEVNV--LDPGT-----HSEG-----------------
--SSQSPGALAIQP-----QSPKSSNKKDRKQNWSE-SSE-DFAQ---------------
A-QDSSQEGLLCKGAGATAHEKDHPGEPALVSASRPHNSSK-----------KART--EK
AEGKAHAHTTTRPAFLDRGNYIRLNMKQKCYVRVGANRGRLLRKQVWKQKWKKKGEQFGG
SRPRA-TVQD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFQCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGSTMTF------Q-EEGGG--DDKQPISTLEE
DTQMASTPSCHLSS--EDTDPDGPKLQVP------------CP-PRPVLPFYPPGPSGHI
A---------ETPAEVFQALQQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQEHAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPACLKAARLHSGMTKKQREAVLKKVK-A
AQVHVLLVSPEALVGCWAKGPASLPQATQLPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVHCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 873)

TARDVAQHLGIAEELELSG-LAT
IPANLHLSVSVDRDSDQALVTLLQGDRFCTLD

PF00271 // ENSGT00550000074520_1_Domain_3 (873, 986)

SIIIYCTRRKDTERVAALLRTCLSVVR-
------EPRHGGCGPEAIAEAYHAGMCSQERRRVQQAFMQGHLRVVVATVAFGMGLDRPD
VRAVLHMGLPPNFESYVQAIGRAGRDGKPAHCHLFLQPQGEDLWELRRHAHADGIDFLAV
KKLVQRVFPSCTCTR--------------R-----------PMSKPMLEEAKEHNSQQIH
PVLGQACLGHKRAFPVQSTVQALDMTEEAIETLLCYLELHPRRWLELLPCTYAHCHLHCP
GGSAQLQALA--HRCPPLAACLAKYPPKDTSR-GSSSLDFDMVELADSMGWDLSSVRRAL
YQLQWDQEPKKGAPRGTRVLVEFSELAFHLHSPGDLTDEEKDQICDFLYSCVQAREHKAL
AHLHQISMAFRSVAFPSCGPCLEQADEERSNQLKTLLSHYFEEEE---------EEAVKD
EQSPEPGQTE-L--QDWEDHIRRDIRQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QVYGQDRRFWRKYL--------HMNFHALMRLATEELLLRGR------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 139)

ATVRARLQEWERAFVRLHGRRPAKGDVEA-APEETRALYREYR-NLKQA
VRQADD-RHRVLEQ--SLAEAAEEVQEPSCWGPHLSRAATQNTQSM-PKQSL-LSSVQDY
GKRLKANLKNTP-----Q

ENSGT00550000074520_1_Linker_0_1 (139, 491)

TGPTLSRKLQPQKRSLSTV-PTPRP-------PGSKTESAC-
PD-----EANDALPRVPEPRPRLGQLQQLRSSLSRRLTSLDPGWLERCHNRVSDLLEVPG
ACGLD-LSAEQSQ-----PQMSGKVNV--ADPNI-----QSEV-----------------
--SAQSPEAIAQQPAQVLSQSPNSINSKGRKRKWNE-KGE-DFAQ---------------
A-QPSSQAEPLSEGAGATAHGQEPPGEPTQVNVPQPCNSSN-----------QART--EK
AKGATHLHTSPRPASLDRGNYIRLNMKNKCFVRVGANRGRLLRKQVWKQKWKKKQAAFGG
SGPRA-KDKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGPTPTG------Q-EEGDR--DDKQPISTLKE
VAQRTGTASCHHT--GEETEPAAPELQVP------------HC-PTPMSPLYPPGPLGQV
A---------ETPAEVFQALERLGYRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPSCLKAACLHSGMTKKQRESVLKKVR-A
AQVHVLIVSPEALVGCGARGPGSLPQAAQLPPIAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAQHLGIAGEFELSG-STN
IPANLHLSVSMDRDLDQALVTLLQGDRFRT

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIIYCTRRKDTERVAALLRTCLSMVG-
------DSRPRGCGPEAIAEAYHAGMCSQERRRVQQAFMRGHLRMVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFMHPQGEDLWELRRHAHADSTDFLAV
KRLVQRVFPPCTCSQ--------------R-----------PVSKSPPEEVKEHSGQQTY
PVLGQACLGHERALPVQSTVQALDMTEEAIETLLCYLELHPRHWLELLPWTYAQCHLHCP
GGSAQLQALA--HRCPPLAACQAKWPPKDTSQ-GRSSLEFGVVELADSMGWKLASVRQAL
HQLKWDPEPKKGAAQGTGVLVKFSELAFHLHSRGDLTDEEKDQICDFLYNRVQAREHKAL
AHLHQMSKAFRSVAFPSCGPCLEQSNEEHSNQVKTLVSYYFEEEEE-E-----EEETMTD
TQGPKPGQTQ-L--QDWEDQIRRDIRQLLSLRPEERF----SGRAVARIFHGIASPCYPA
QVYGLDRRFWRKYL--------HLDFDALMHLATEELLLRGR------------------
-----------------------------------------------------------

-------MERLW

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 84)

NLRAHLQAWERAFARQHGRRPAQEDVEA-APEETRALYRKYR-ALKQA
MRQRAG-EPCSHKQ--SLSASAQ

ENSGT00550000074520_1_Linker_0_1 (84, 491)

EAPEPSCWGSHLNRAAAQSPQPT-PALSP-QGSAQEY
GKRLKANLKVTL-----QADPALDHRCQPPGRLLSKM-PTLKP-------PGPGTSPTS-
PE-----ELGDALTKPSEPQPRPGRLQQLRASLSLRLGSLDPDWLQRCHSGASDYLQASE
PSS-----TKESQ-----PVTPGDVPV--LVSNT-----CSEA-----------------
--RSQDPHAPVLQAAQTSADSPQLSSHRGKKRKWTKEDGS-SPVP---------------
VQWDNIQARLQSEGAGAAALEEDPAGGAVQAQPPELYSGTS----------RPAEA--GK
AASTPRPRTCPQSAGQDKGNYVRLNMKQKRYVRGGALRGRLLRKQAWKQKWQKKREHFGG
GRPRA-MTEK

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFQCGQLGHWKSQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QLGPTRNP------Q-KEGDEDKDDMQSFPALEQ
TTQRTDAACCHLPG--KDTEPAGPELQ------------APNT-VPSVLPLYPPGPCGQV
A---------ETPAEVFQALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERTIMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRGPCLTLVISPLLSLMDDQ-LSHLPPCLKAACLHSGMTRKQRESVLQKVQ-A
AQVHVLMLSPEALVGAGSGSPVHLPQAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RICKV------------LRECMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAHHLGVAEELSPRE-APA
IPANLYLSVSRDRDPDQALVTLLQGDRFRS

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 986)

LDSVIVYCNRREDTHRVAALLRTCLYAVQ-
------DPKFRGRGPTAVAEAYHAGMCNRERQRVQQAFMKGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFENYVQGVGRAGRDGLPAHCHLFLQPQGEDLRELRRHVHADGADFLAV
KKLMQYVFPPCTCT--KQEGQEGG-NSGTR-----------PAAESPPPKAKERGGCPAA
FGQGRACPGHERALPVQPTVQALDMPEEAIETLLCYLELHPQHWLELLPATYAHCRLYCP
GGTNQLQALA--HRCLPVAACWARWPPENTSQ-GSCSMEFNVVELVDSMGWELPPVRRAL
HQLQWDRESRTGVLQRTGVLVEFGELAFHLRSPGDLTAEERDQVCDFLYSCVQTRERKAL
AHLRRMFQAFHSVAFPSCGPCLEQPDEEHSAQLKALLNHYFEEEEEEEEEEEEEEGDVKD
KQSPEPGQAQ-L--QDWEDQVRHDIRQLLSLRPEERF----SGRAVARIFHGIGSPCYPA
QVYGRDQRFWRKYL--------HLNFHALMRLATEELLLAGP------------------
-----------------------------------------------------------

-------MEPLRDLRARLLAWERAFRRQRGRRPGQADVAA-ASEETQALYREYR-ALKQV
LGQAGRVQPRSPEQ--SAPVATWEEL-EPCWGPHLNRAS-KSPHPT-PAPXXXXXXXXXX
XXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXX----XX-------XXXXXXXXX-
X------XXXXXXXXX---XXX-X-X--XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXXXX---XXXXX-----XXXXXXXXX--XXXXX--------------------------
--X--XXXX-XXXX--XX-XXXXXXXXXXXXXXXXXXXXX-XXXX---------------
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------X--XXXXX--XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX-X------X----XX-XXXXXXXXXXXX
XXXXXXX-----XX-HKHVGRARLELLGP---------SEPQ-PPDAMPPLYPLGPSGQV
A---------ETPPEVYQALEQLGYQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQEQAIMQVLSGVSTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTIVISPLVALMDDQ--SGLPPGLKAACLHSVMTRKQRESVLQKVR-A
AQVHVLMLSPEALVGAGAGSPAHLPPASQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKA------------LREHMGVRCFLGLTATAPRSTALD

ENSGT00550000074520_1_Linker_2_3 (822, 908)

VAQHLGVAQGLGPCGLPAT
IPANLRLSVSTDRNPEQALVTLLQSRRFRSLNSVIVYCHRREDTERVAALLRTCLHETS-
------G

PF00271 // ENSGT00550000074520_1_Domain_3 (908, 987)

PG---GRPKAVAEAYHAGMCGQERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGMPPSLESYVQAVGRAGRDGQPAHCHLFLRPQAEDLQELLRHVHADTVDFLAV
KKLVQSVFPPCSCAHPPLEDSESR------------------GQAAFPPEAGQHNNRDTA
REPRRACRGHTRALPVQPTEQALDMPQEAIETLLCYLELHPQRWLELLAPTYAHCRLHCP
EGATQLSTLA--LRCPPVAVCLARQPPKDPGG-GSTSVEFDVVELADSMGWELARVQRAL
YQLQWDES-------GARVLVEFGELAFHLHCPRDLTAEEKDQL----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------

------------------------------------------------------------
------------------------MLEPSCWGNHLNRAATQSPHPP-SRWSP-QESAQDY
GKRLKANLKGSL-----QARSTLGRIPRLAQRSSSKI-PSPEP-------PGAAAAPIS-
PE-----NVNQVLPQPPRPQLRPGRLQQLRASLSLRLSSLDPEWLQRCHNRTPDFLEVSR
TCQPG-LGAEDSQ-----LLTPAVASV--LSLSA-----GPEV-----------------
--PLQGPEAPALPAAGVSAGKCQPGDRQGKKRRQSGELEG-SLAQ---------------
TQQGTDQAGPMPEGAGAAGPAEDCTEQPVKTQPPGRTPAS---RS---------------
--------------VQDRGNYVRLNMKQRRYVRGRALRGRLLRKQAWKQKWQKKEECFGG
GQPRG-PAQDSCSQHGQLSHWASRCSQPEPLLAPQKE--DVKVDGAQT------QPTLQE
ASLRTGAACCQLSAGEEDAEPGAPELLVP---TGPSVSRMPCP-PLSVPPLYPPGPSGQV
A---------DTPAEVFQALEQLGHHAFY

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 816)

PGQEPVIMRILSGMSTLLVLPTGAGKSLCYQ
LPALLYFRRSPCLTLVISPLMSLMDDQ-LSGLPPGLKGACIHSGMTKKQRDSALQKAR-A
ARVQVLMLSPEAVVGPRAGT--LLS---QLPPVAFACLDEAHCL----SQWSHNFRPCYL
RVCQTL------------RDQMGVHCFLGLTATAT

ENSGT00550000074520_1_Linker_2_3 (816, 920)

RSTALDVAWHLGVTEESVLRGP-AT
IPANLHLSVSSDRDPDQALVTLLQSDRFRALDSIIIYCHRREDTERVAALLRTCLCEAR-
------DPGPHGRALEAVA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

EAYHAGLCSQDRRRVQRAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFENYVQAVGRAGRDGQPAHCHLFLRPQGQDLRELRRHVHANAVDFFTV
KRLVQRVFPPCSCAR--QPPEQEGGRSKEE-----------CLAGAPVAASAQDP-GQPS
VPHTPRCPGHERVLPVQPTVQALDMPEEAIETLLCYLELHPRRWLKLVAPTYARCHLRWP
GGPTQLQALA--RRCPPLALCLAQQHPDTK-G-GCSSVELDLVKLADSMGWELGPVRRAL
LQLQWEPEPKTGVPRGTGVLVEFREMAFHLYSPGDLTAQERDQICDFLHSRVQAREQEAL
AHLHHTFRAFHSMAFPSCGPCLEQPDWERSSRLKALLSHYFEE-S-E------QPGGLET
EDDPELGQDR-VSVRAWRGGGH----TPASCWHHDKPCTTLSRAEERAVEAGLA------
------------------------------------------------------------
-----------------------------------------------------------

------------------------------------DVEA-APEETKELYREYR-VLKRA
LESTALADAGNPEQPSPALEQENKATEPGCWGAHLNRNAVGIREQT-L-----GSSVPYF
GRKLKSNLKAVIRVSV-Q-----GDSSESRSRSQKTA-PSPNV-------LGEVQSAKCT
PP-----SPYSGRPGGVTPNPRPGRLRQVRRSLNRRLSSLDPGWLERCQNGTGERSPGRE
AISAPPPPPPGPQTRPEDPSPPGRC-----------------------------------
-----RPRAPAAKKRQRESGEEEEAAAPKRQRKRPDDPVS-RDRQ---------------
ASDSSGRHGKKPVQMAAPEAEEDLLGEIAGANTPRPLASVSTRRYFLVEGG---------
--GTFEMGGSVGAAPKASGNFVRLNMKKKCYVKASALRGNHLRKQVWKQKWQKKGQQFGG
GGSHGSHEND

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 506)

TCFRCGGRGHWAAQCRRRGAPSHQ------PPEQESSHAQEEPPLPTLEE
VAQRTNTAYSKIPG-DEGTEVTGSELLVP---TERPAHVAPAP-PPAVKPLYGLGPSGQV
K---------ETPAEVFQALSQLGHKTFRPGQEAAVMRILSGESRFPLNPPSPR--RCY-
-PXLFFTSPHQFFEHLPGPLASVSARQ-VSGLP

PF00271 // ENSGT00550000074520_1_Domain_2 (694, 727)

PGLRAACVHSNMSKKQRDLAVEKVK-A
GQVEVL

ENSGT00550000074520_1_Linker_2_3 (727, 920)

LLSPEAV--------GCLPAAAQLPPMAFACIDEAHCL----SQWSHNFRPCYL
RLCKV------------LRERLGVKCFLGLTATATRATARDVAQHLGTHEGVDLGVHLAA
IPPNLHLSVSLDRDKDQALVTLLKGERFRSLGSIIVYCNRREETVRVAALIRTCLQGTP-
------GP-PEGRGQEALA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

EAYHAGLSGSERRRVQRAFMRGRLRVVVATVAFGMGLDRPD
VRAVLHHGLPRSFESFVQEIGRAGRDGQPAHCHLFLQPQGEDLNELRRHIYADTVDYFTI
KKLVQKVFLHCTCSQLFKQQQQQQALPDPR-----------P--------------QEAY
DPRGRVCSGHERAFSVQLSVEALDMREEAIETLLCYLELHPRRWLELLPPTFATCHLRCS
GGPPQLRSLA--RSCPPVAACLARQRPAGTEKPLGDSLEFDVVELADAMGWDVAPVRRVL
RQLQWGPTPEKGGSGRTGVLVEFGDLAFHLRAPGDLTDSERDEICDFLHHRVRARERTAL
AQLRTSFRAFRSVAFPNCGPCTERVDEERSDRLKALLTRYFEEEEEASPDEG--PT-ENE
DDDQHLGQAR-L--QDWEDQIRSDIRQFLSIRQEEKF----SGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKYL--------HVDFHQLIRLATEEILRWK-------------------
-----------------------------------------------------------

-------MDRLRG

PF11719 // ENSGT00550000074520_1_Domain_0 (14, 64)

VRARLQEWERAFARLHGRRPEQADVEV-APEETRALYREYR-TLKQA
VRQ

ENSGT00550000074520_1_Linker_0_1 (64, 491)

AGG-GCLIPEQ--SLTTVAEEAQEPSCWGPHLNRAATQNAQPT-PKQSP-RSSVQDY
GKRLKANLKDTL-----QAGPNLGRKLHPQKRPLSMM-PTPRW-------SSPQTAPTC-
PG-----EANDVLP-----PPRSGRLQQLQASLSQRLSSLDPVWLQRCHNEASDFLEAPG
IYNPG-LSAEESQ-----PLLSGKVMV--LDPGS-----HSEA-----------------
--SSL---------AQVDSWSPHPSKSQGKKQKRNE-NWE-DSAQ---------------
VQQDSSQARHLREVVGATALEKDPRGEPMQVNLSRPCNSSR-----------QTRT--EK
AEGPNQLRISSRPAILDKGNYIRLNMKQKCYVRVGALRGRSLRKQVWKQKWQKKGEHFGG
GRSRA-TVKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFQCGQFGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QLGSTLTF------Q-KKRGK--DDTQPIPTLE-
VAQRTVTTSCHHSG-EKST---EPQLQVP------------YS-PCPVLPLYPPGPLGQV
A---------ETPAEVFQALEQLGYQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQEHAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVVSPLLSLMDDQ-VSDLPPCLKAACLHSGMTKKQRESVIKKVQ-A
AQVHVLILSPEALVGAGARGSASLPQASQLPPVAFACIDEIHCL----SQWSHNFRPCYL
RICKV------------LRECMGVHCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 870)

TARDVAQHLGIAEELDLCG-PAT
IPINLHLSVSMDRDSDQALVTLLQGDRFR

PF00271 // ENSGT00550000074520_1_Domain_3 (870, 986)

TLDSIIVYCNRREDTERVAALLRTCLSAVR-
------DSGQKGRGPEAIAEAYHAGMCSQERRRVQQAFMQGHLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGKPAHCHLFLQPQGEDLQELRRYAHADGTDFLAV
KKLVQRVFPPCTCTW--------------L-----------PP------------GKEGA
PVLAQACLGHKRALPVQSTVQALDMPEEAIETLLCYLELHPQRWLELLPSTYAHCHLHCP
EGHAQLQALA--NRCPPLAACYAKWPPKDTSQ-GSSSLEFDMVDLADSMGWELASVRRYL
HQLQWNQEPRTGAPQSTGVLVEFRELAFHLHSPGDLTAEEKDEICDFLYSRVQAREHKAL
AHLRQISKAFRSVAFPSCGPCLEQPDEERSNQLKMLLSRYFEEEEEAE-----E-----N
EESTEPGQAQ-L--QDWEDHIRRDIRQLLSLRPEERF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLNFHALMRLATEELMLWGR------------------
-----------------------------------------------------------

--------------------------------PPQEDVEA-APEETRALYREYR-ALKGA
LGRAGGIGPHSPKR--SLLATAEEMQEPSCWGPHLNRAATHSPHPTVSGPSP-VGSVPDY
GKRLKANLKATL-----QGGPALGRIPRTPRRPSSKT-PSLGP-------PGGEAVRIF-
PE-----VVSEVLLQPHGPQLRPGRLQQLQASLSLRLSSLDPDWLQRCHNGAPDFLGASK
ACQPN-LGVQESQ-----PLTPGVPSV--LGPST-----GPE------------------
--------TRALQIAGVSAGSPRPGNSQDKKWRWSREPEG-SPAQ---------------
AQQDGGQAGSLPEEAGAAEHTGDCPGEPLWVQPPSAPRAS-----------RRDRV--GQ
ALGMLSSYVLSRSALRSGGNYVRLNMKRKRSVRGPALRGRLLRKQMWKQKWQKKGERFGG
GQPRA-AAKNSCFQCGQLGRWSSQCPQSEPT--------LDPQKSSEDEEDVQTQLTLEE
VVRRTGTASCQLPVSEKDTEPAGPEPLVT---VERPVPQAHCP-SPIVPPLYPPGPSGQV
A---------ETPAEVFQALEELGHQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQERVVMRILSGMSTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-MSGLPPCLKAACIHSGMTRKQQESALKKVQ-A
AQVHVLMLSPEALVGAGAGIPGRLP---QLPPVAFACVDEAHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVHCFLGLTATATRSTARD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VAQHLGVAEELVLRGP-VT
IPTNLYLSVSMDRDPDQALVTLLQSDRFRALSSVIVYCNRREDTERVAALLRTCLREAR-
------DLGR

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

RGQAPKAVAEAYHAGMCSRERRRVQQAFMDGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPASFESYVQAVGRAGRDGQPAHCHLFLQPQGQDLQELRRHVHADATDFLAV
KKLVQCSFPPCTCTHAQRPLEQDGAESQER-----------PVA-----VSPREA-KQPN
SERTARCPGHERALPVQPLVQALDMPEEAIETLLCYLELHPQRWLELLAPTYAHCRLRCP
GGPPQLQALA--HRSPLLALCLAQQPLESTGG-GSYSVEFDVPKLADSVGWKLASVRQAL
RQLQWEPEPGTGAPRETGVLVEFRELAFCLHSPGDLTAPERDQICDFLYSHIRAREQEAL
ARLRRTFQAFHSVAFPSCGPCLEQPDEERSARLKTLLSCYFEE---E------GPGRVGD
EQGPEPGQTG-I--QDWEDQVRQDVRHLLSSWPDQQF----SGRAVARIFHGIGSPRYPA
QVYGRDRRFWRRYL--------HLSFPGLMRLATEEILQWGH------------------
-----------------------------------------------------------

-------MEQLW

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 73)

NLRARLQEWERSFAVQHGRRPGQ-DVEA-APEETRALYRKYR-ALKQT
MSQRGG-GPHRP

ENSGT00550000074520_1_Linker_0_1 (73, 491)

KQ--LLSTAAKEAPESGCWGSHLNRAATQNPQPA-PVLSP-QGTAQEY
GKRLKTNLKVTL-----QVRN--ESRLIPPGRLLSKM-PTLKP-------VGPGTPPAS-
PE-----ELISALTKPSEPQPRPGRLQQLRASLSLRLGSLHPGWLQRCHGRPLDSLETSE
ACG-----TEESQ-----SLTPGELAV--FGSNT-----CPET-----------------
--PSQGPD--VPQATQTSAGRPQLSSHRVKKRRWTKENGS-SPV----------------
---------LQSEGAGAAVF-EDPIGGAIQAQPSQLYCGTS----------RPAKA--EK
AEITSRPHTSQ-TTTLEKGNYVRLNMKQKRYVRGGALRGRLLRKQVWKQKWQKKREHFGG
GGPRA-IVEE

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQFGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QLGPTLPP------Q-KDGDEDKDDTQTFPTVEE
VTQRINTAC-------KDTEPAGPELQ------------VPHT-VSSVLPLYPPGPSGQV
V---------ETPAEVFQALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQEHTIMRILSGISTLLVLPTGAGKSLCFQ
LPALLYAQRSPCLTLVISPLLSLMDDQ-LSSLPPCLKAACLHSGMTKKQRESVLQKVQ-A
AEVHVLMLSPETLVGAGSRGPISLPQGARLPPVAFACIDEAHCI----SQWSHNFRPCYL
RICKV------------LRECMGVQCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 872)

AHDVAQHLGVAKELGPRE-AAV
IPANLHLSVSIDRDPEQALVTLLQGDRFRTL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSIIVYCNRREDTERVAALLRTCLFAGQ-
------DPKLRGRTPTDVAEAYHAGMCSRERQRVQRAFMKGQLRVIVATVAFGMGLDRPD
IRAVLHLGLPPSFENYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHTDGADFLAM
KKLMWCVFPPCTCN------------SETR-----------PAAEALPQEAKQHDGCPAD
SGQGRACPGHERALPMQPTVQALDMSEEAIETLLCYLELHPQHWLELLPATYARCHLYCP
GGANQLQALA--RRCPPVAACWARWPPENTKQ-GSCSMEFNVVELVDSMGWELSSVRQSL
HQLQWDQEPRSGMLQSTGVLVEFGELAFHLRSPGDLTAEERDQICDFLYSCVQTREHKAL
ARLRQIFQAFHSVAFPSCGPCLEQPDEERSARLKALLSCYFEEEEE-------EEEGCVD
RQSPEPGQAQ-L--QDWEDQVRHNIRQLLSLRPEESF----SGRAVARIFHGIGSPCYPA
EVYGRDQRFWRKYL--------HLNFHGLMRLATEELLLAGR------------------
-----------------------------------------------------------

-------MERLRDVRERLQAWERAFRRERGRRPSQDDVEA-APQETRGERAGG-------
-RQVGG-GPGSTLT--PPPARPRSAPESHCWGPHLNRAATHSPQHT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRSSSKT-PTPNP-------PGTRPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQACLSQQLASLDLDWLQRCHSEIPDFLGAPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSPDPEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPAQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPPQPCSSLSTPRYHRFSTSSQARA--GK
AEGTAHLHI-SRLARHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPAGPEPLVP---APQPVPGVPGL-ASTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLSPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVNEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 987)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRAPKTTAEAYHAGMCGRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGTMGGEK-----------PVPKYSSQEAEQLGVHQAA
LGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPRHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ARLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPKEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAC------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 64)

DVRERLQAWERAFRRERGRRPSQDDVEA-APQETRALYREYR-ILKRT
VGQAGG-GPRSSEL---LPVAVEEAPESHCWGPHLNRAATHSPQHT-PGRSC-QGSVPDY
GQRLKANLKRTL-----QAGPALGRRPWPLGRSSSKT-PTPNP-------PGTGPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQASLSQQLASLDLDWLQRCHSEIPDFMGAPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSPDPEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPTQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPLQPCSSLSTPRYHRFSTSSQARA--GK
AEGTAHLHI-SRLARHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPTGPESLVP---APQPVPGVPGL-ASTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLSPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVNEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGCAPKTTAEAYHAGMCGRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHTNGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGTMGGER-----------PVPKYSSQEAEELGVHQAA
PGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPRHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ARLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAC------------------
-----------------------------------------------------------

-------MERLREVRALLQAWERAFRRQRGRRPVQEDVEA-APEETRALYREYR-ALKET
LLPASSAGPRGPVQ--APPEAAEEVPEPSCWGSHLNRAVTQSLPAA-AGPSP-RGSVPDY
GKRLKANLKDAL-----QAGPALRRIPRPPQRPPPTV-PSPGL-------PAAGASPAS-
PE-----EVSEVLPQLPRPQLRPGRLQQLQESLSLRLGSLDPGWLQRCHET-EGFLGTSE
ACQPV-PGTGEPP-----PLTSGVPSD--PGPST-----GPEA-----------------
--PFLGSEAPAMKVPGVSAGNPLLGGSQGKKRRKSGELKGTAAAQ---------------
ARQHSSQEGSPPEGARAVLHAEDCPGEPTQAQLLTGPSAP-----------RLGQG--GD
AMGKAHLYVPSRPAARDRGNYVRLNLKQKRYVWGPALRGRLLRKQAWKQKWKKKAEHLGG
GQSNA-PVK

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

DSCFRCGQLGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 629)

RPGPKPTRV-----PKKEGGEEEDDMQMLPTLEA
VAQRTHTACGQLRG-EEDTDPAGSELLVP---MEAPVPGGPCP-SPAVPPLYLPGPLGQV
A---------ATPVEVLQALEQLGHRAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQEHAVMRILSGMSTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVISPLLSLMDDQ-VSGLPQGLKAACVHSGMTRKQRDSALQRAR-A
GQVHVLMLSPEALVGAGTGSPACLT---QLPPVAFVCIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRESLGVRCFLGLTATATRSTTLD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VAEHLGIAKEGVLRGP-VT
IPANLHLSVSMDRDPDQALVTLLRGDRFRTLDSVIVYCNRREDTERVAALLRTCLPEAR-
------APGP

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

GGQAPEAVAEAYHAGMCSRERRRVQRAFMEGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYIQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANAIDFLAV
KKLVQRAFPPCTCAQRRSEQ--EGGERQEG----------------------CSS-KQPS
HEPTARCPGHKRALPVQPTVQALDMPEEVIETLLCYLELHPQHWLELLAPTYTRCCVRYP
GGPTQLQALA--SRCVPLAACLAQQLPGNTGG-GSSTVEFDVVELVDSMGWELAPVRKAL
HQLQWDPEPRKGVPRGTGVLVEFSELAFYLHSPGDLTAQEKDQICGFLHDRVQAREREAL
ACLRLMFQAFHSVAFPSCGPCLEKPDDDRSTRLKALLSHYFEEEG---------PGGEEE
AQGPEPGQVK-L--QDWEDQIRRDIRHFLSSWPEQQF----SGRAVARIFHGIGSPCFPA
QVYGRDRRFWRKYL--------HLNFHALIKLATEEILLWGR------------------
-----------------------------------------------------------

------------------------------------------------------------
--------------------------EPTCWGPHLNRAVRQSPHPT-PAPST-QRSVPDY
GKRLKANLKGTL-----QAEPALGHVPRAPRRPSSET-PALRL-------PDTGATLTS-
P------GLSQVPPQCPGPQPRPGRLKHLQSSLSLRLGSLDPGWLQRCHDGAPDLLGVPG
ACRPS-LGAEELC-----SPGEGSQPP--TSGVL-----AAPR-----------------
--TCSGSEAPVLEGASDNK----RSIQPNKKQRQSGDAGG-APSQ---------------
AQWDSSYVGPQPKDAGAAEPKEDPLGE----QSPRPPSGPTTPRWVTSE---LSWV--RR
AVGTAHPDISPRSTLQEGGNYVRLNLRQKRYVRGPALRGSQLRKQVWKQKWQKKQECFGG
SHPKS-TFK

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

NSCFRCGQLGHWASQCH

ENSGT00550000074520_1_Linker_1_2 (507, 629)

QPEPAP-A------Q-KKGTR-DEGTQLLSILEE
VAQKTGAAHCKLPD--EDTGSARP-----------------HT-PNVVLPLYLPGPLGQV
A---------ETPPEVFQALGQLGYQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQEQAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTIVISPLLALMDDQ-VSRLPPGLKAACLHSGMNRKQREGVLRKVL-A
AQVHVLMLSPEALVEAGTGGPVCLPPASQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVHCFLGLTATAPRSTALD

ENSGT00550000074520_1_Linker_2_3 (822, 911)

VARHLGVTEGPSPSGLPAT
IPTNLHLSVSMDRDPEQALVTLLQGERFRSLDSAIVYCNRREDTERVAALLRTCLHK---
------TPGP

PF00271 // ENSGT00550000074520_1_Domain_3 (911, 987)

RGGVPEAVAEAYHAGMRAQERRRVQQAFMRGRLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGQPAHCHLFLQPQGEDLQELRRHVHAHTVDFLTV
KRLVQTVFPPCSCAH--PSPEGGG----KR-----------EQ-VTLPPETRQCG-SQDT
PSGSSACLGHTRALPVQPMEQTLDMPQEAIETLLCYLELHPQRWLELLAPTYAHCRLHSP
RGPAQLSALA--LRCPPVAVCLAQQPPEDTGG-GSSSVEFNVVELADSMGWELAPLRRAL
CQLQWDQNPRSGMPQGTGVLVEFGELAFHVHCPRNLTAEEKDQLCEFLHGRVQAREQEAL
ARLRRTFQAFHSVAYPSCGPCLERPNEERSVQLKTLLRCYFEEETL-------GPQGMED
EEGPEPGQAR-L--QDWEDQIRRDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVFGRDRRFWRRYL--------HVSFHALMRLATEELLLRGH------------------
-----------------------------------------------------------

-------MERLRDVRLQLQTWERAFARLHGRRPDVE----AAPEETRALYREYR-TLKQA
VRQANG-GHRIPEQ--SLPAAAQKVPWPLTPA--SNHL----------------------
--TIWPNGRSQE-----QSGLTQSRRLQPLQRPLYKK-PTPRP-------PGSSPACTC-
PD-----EVSDVFPQLSEPQPKPGRLRKLQASLALRLSSLDPDWLERCQNRSSDFLEVPN
TCRPG-LGLEDSQ-----PLISGKLII--FGTSN--------T-----------------
--PSQGPEKAAQ----VALQVSQPGNSQDRKQRWNENT-G-DSAQ---------------
AQQDSSQGRLRSKGTGAAAVGKDPSGEPVQMKL------------LSCSSSSQAKV--GK
AEGTAHQQASPRPAALDRGNYVRLNMKQKHCVQRGALRGRLLRKQVWKQKWKKKGEHFGK
GGPRA-TVKDSCFQSWQFDHLASQCSWLGKAFAL------G-IV----AGYHRLFSTL-E
KAQKTDTACY--HL--SDTEAVGPQV------------QVPYP-PPPVPPLYPPGPSGQI
A---------ETPAEVFEALKQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQECTVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCITLVISPLLSLMEDQ-VSGLPLCLKAACLHSGMTGKQRESVLKKVL-A
AQVHVLILSPEALAE----GGASLPQASQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RICKV------------LRKRMGVRCFLGLTATATLST

ENSGT00550000074520_1_Linker_2_3 (819, 872)

AREVAQHLGVAEELDLRG-SST
IPANLHLSVSMDRDPDQAVVTLLQSDRFQTL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSIIIYCNRREDTERVAALLRTCLPVAR-
------DPGPTGRVFNDVAEAYHAGMCSQERRRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLKPQGEDLRELRRHAHADGTDFLAV
KKLVQRVFPPCACT--------------QR-----------PVAKSPPQETKY-SSHQVA
HMQGPACQGHERALPVQPTVQALDMPMEAIETLLCYMELHSQHWLELLPVTYTHCHLHCP
GGHAQLQALA--HRCPPLAAYLAKWPPEDPNQ-GSSSLEFDMVELADMMGWELASIRRSL
HQLQWDQEPRTSTPRRTGVLVEFRELAFHLHSPGDLTAEEKDQICDFLYTRVQAREHKAL
AHLRQIFKVFRSVAFPSCGPCLEQPDEDRSAQLKTLLSHYFEEEEE----------IMED
DEGPEPGQAQ-L--QDWEDSIRRDIRQLLSLRSEERF----SGRAVARIFHGIGSPCYPA
QIYGQDRRFWRKYL--------HLNFHALMHLATEELLLKG-------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 64)

DVRELLQAWERAFRRQSGRRPGKEDVEA-APEETRALYREYR-SLKKA
LGQAGGVEPHGSGQ--SLPVAAEQMLEPSCWGHHLNRAATQSPHPP-SRWSP-QESAQDY
GKRLKANLKGSL-----QARSTLGRIPRLAQRSSSKI-PSPEP-------SGTAAAPIS-
PE-----NVNEVLPQPPRPQLRPGRLQQLRASLSLRLGSLDPDWLQRCHNRTPDFLEVPR
TCQPG-LGAEDSQ-----LLTPVVESV--LSPSA-----GPEV-----------------
--PLQDPEAPALPAAAVSAGKCQPVDRQGKKRRQSGELEG-RLAQ---------------
TQQGTDQAGPLPEGAGAAGPAEDCPDQPVKAQPPGRTPAS---RS---------------
-------------AIQDRGNYVRLNMKQRRYVRGRALRGRLLRKQAWKQKWQKKGECFGG
GQPRA-PAQDSCSQHGQLSQWASRCPQPEPLLVPQKD--VKVADGAQT------QPTLQE
ASLRTGAACCQVSAGEEDAEPGAPELLVP---TGQSVSRMPCP-PLSVPPLYPPGPSGQV
A---------DTPAEVFQALEQLGHHAFY

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 816)

PGQERVVMRVLSGMSTLLVLPTGAGKSLCYQ
LPALLYFRRSPCLTLVISPLTSLMDDQ-LSGLPPGLKGACIHSGMTKKQRDSALQKAR-A
ARVQVLMLSPEALVGAGAST--LLS---QLPPVAFACLDEAHCL----SQWSHNFRPCYL
RVCQTL------------RDQMGVHCFLGLTATAT

ENSGT00550000074520_1_Linker_2_3 (816, 920)

RSTALDVAWHLGVTEESVLRGP-AT
IPDNLHLSVSSDRDPDQALVTLLRSDRFRALGSVIIYCHRREDTERVAALLRTCLCDAQ-
------DPGPHGRALEAVA

PF00271 // ENSGT00550000074520_1_Domain_3 (920, 987)

EAYHAGLCSRERRRVQRAFMEGRLRMVVATVAFGMGLDRPD
VRAVLHLGLPPSFETYVQAVGRAGRDGQPAHCHLFLRPQGQDLRELRRHVHANAVDFFAV
KRLVQRVFPPCACAR--QPPEQEGSRSEEG-----------HLAGAPVAASAQDS-GQPS
VPHTPRCPGHERVLPVQPTVQALDMPEEAIETLLCYLELHPRRWLKLLAPTYARCHLRWP
GGPTQLQALA--RRCPPLALCLAQQHPDTK-Q-GCSSVELDLVELADSTGWELGPVRRAL
LQLQWDPEPGTGVPQGTGVLVEFRETAFRLHSPGDLTAQERDQICDFLHSRVQAREREAL
ANLHHTFQAFHSVAFPSCGPCLEQPAWERSSRLKALLSHYFEEES-E------QPGGLET
EDDPELGQDR-LQ--DWEDQIRRDIRQLLSSWPEQRF----SGRAVARVFHGIGSPCYPA
QVFGRDRRFWRKYL--------HLSFPALMHLATQELLLWGR------------------
-----------------------------------------------------------

------------------------------------------------------------
MGLRGR-GPRSPKP--LLPAAAKEAPESGCWGSHLNRAATQTPQPT-PMLSP-RGSAQDY
GKRLKTNLKVIL-----QAEPALGCRHQPPGRLLSKL-PTLKP-------LGPGTPPTF-
PE-----ELIDKLTKPSEPQPRPGRLQQLRESLSLRLSSLDPGWLHRCHNGPLDFLEASE
ACS-----MEESQ-----TLTPGELAV--FGSNT-----CLEA-----------------
--PSQGPDAPVPQATQTRAGSPQLSSHTVKKQRWTKENDS-SPVP---------------
AQWDSNQARLQSEGAGASVL-EDPTEDATQAHPRQLYSGTS----------RPAEV--GK
AEITPRSHTCSQTAIRDKGNYIRLNMKQKRYVRGGALRGRLLRKQAWKQKWQKKREHFGV
GGPRA-MVEE

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

SCFRCGQFGHWASQCP

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QLGPTLIS------Q-KEGDKDKGDTQTFPTLEE
VTQRINTACCHLPS--KDTEPAGPELQ------------APHT-VSSVLPLYPPGPSGQV
V---------ETPAEVFQALEQLGHKAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERTVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVISPLLSLMDDQ-LSSLPPCLKAACLHSGMTRKQRDSVLQKVQ-A
AQVHVLMLSPEALVGAGSGGPVSLPQAAQLPPVAFACIDEAHCI----SQWSHNFRPCYL
RICKV------------LRERMGVQCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 872)

ARDVAQHLGMAEELGPRE-AAA
IPANLHLSVSTDKDPEQALVTLLQGDRFRTL

PF00271 // ENSGT00550000074520_1_Domain_3 (872, 986)

DSVIVYCNRREDTQRVAALLRTCLYAVQ-
------DPKLRGRAPEDVAEAYHAGMCNRERQRVQRAFMKGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPSSFENYVQAVGRAGRDGQPAHCHLFLKPQGEDLQELRRHVHRDGADFLAM
KKLMRCVFPPCTCT--QRERKEGGGDNETK-----------PAAEALPVAAKQPDGCPAA
SGQGRACPGHERALPVQPTVQALDLSEEAIETLLCYLELHPQHWLELLPATYAHCRLYCP
GGTNQLQTLA--HRYPPVAACWARWPPKDTKQ-GSCSMEFNVVELVDSMGWELSSVRRSL
HQLQWDPEPRTGMLQGTGVLVEFGELAFHFRSPGDLTAEERDQVCDFLYSCVQTRECKAL
ARLRRMFQAFHSVAFPSCGPCLEQPDEERSAQLKTLLSHYFEEEEEEE-----DEEGVED
KQSPEPGQAQ-L--QDWEDQVRPNIRQLLSLWPEERF----SGRAVARIFHGIGSPCYPA
EVYGRDQRFWRKYL--------HLNFHGLMLLATEELLLAGR------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 66)

DVRERLQAWERAFRRERGRRPSQDDVEA-APQETRALYREYR-TLKRT
VGQAGG-GPRSSEL---LPVAVEEAPESRCWGPHLNRAATHSPQHT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRSSSKT-PTPNP-------PGTRPVPTF-
AE-----KVSDEPPQPPGPQPRPGQLQHLQACLSQQLASLDLDWLQRCHSEIPDFLGAPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSPDPEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPAQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPPQPCSSLSTPRYHRFSTSSQARA--GK
AEGTAHLHI-SRLARHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWASQ---CPQPV----------------------------
------------SE--EDTDPAGPEPLVP---APQPVPGVPGL-ASTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLSPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVNEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGGAPKTTAEAYHAGMCGRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRLSPEQEGTMGGER-----------PVPKYSSQEAEQLGVHQAA
LGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPCHWLELLATTYIHCRLSCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVEFDMVKMVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ARLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPKEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLQVAC------------------
-----------------------------------------------------------

-------MERL

PF11719 // ENSGT00550000074520_1_Domain_0 (12, 114)

ATVRARLQDWERAFVRLHGRRPAKEDVEA-APEETRALYREYR-NLKQA
VSQADD-GHRVQKQ--SLAKAAEEEQEPSCWGSHLNRAATQNTQSI-PKQSP-

ENSGT00550000074520_1_Linker_0_1 (114, 491)

LSSIQDY
GKRLKANLKNTL-----QGGPTLSRKLQHQKRSLSIV-PTSRP-------PGPRTESPC-
PE-----QANDALPQVPVPQPRQGQLQKLQSSLSLRLSSLDPGWLERCQNRVSDPLEVPG
ACGLD-LSAKESQ-----PQMSGKVNV--ISPDI-----LSEV-----------------
--SSQSPQALAQQPAQVLSQIPKSSNSKDRKRKRNE-KGE-DFAQ---------------
A-QPSSQAGPLSEGAGATAHGQGPPGEPTQVTVPQHRCSSN-----------QART--EN
AKSAAHLPMSPRPASLDRGNYVRLNMKTKCFVRVGASRGRLLRKQVWKQKWKKKQEWFGK
SGPRA-TVKD

PF00098 // ENSGT00550000074520_1_Domain_1 (491, 507)

TCFRCGQFGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 630)

QPGSTLTI------Q-PKGDR--NDKHPISTLGG
VAQKTGTTSCNHS--GEETEPAGPVLPVP------------HC-PTPVLPLYPPGPLGQV
A---------DTPAEVFQVLEQLGHHTFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 818)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAKRSPCLTLVVSPLLSLMDDQ-VSDLPSCLKAACLHSGMTKKQRESVLKKVR-A
AQVHVLIVSPEALVGCGAKGPANLPPAAQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCKV------------LREHMGVRCFLGLTATATRS

ENSGT00550000074520_1_Linker_2_3 (818, 871)

TARDVAQHLGIAEELEVSG-SAS
IPANLHLSVSMDRDSDQALVTLLQGDRFRT

PF00271 // ENSGT00550000074520_1_Domain_3 (871, 987)

LDSIIIYCARRKDTERVAALLRTCLSTVR-
------DSKPRGRGPETLAEAYHAGMCSQERKRVQQAFMQGHLRMVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFLHPQGEDLWELSRHVHADSTDFLAV
KKLVQRVFPACSCAQ--------------R-----------PM--SPLEEVKEHSGQQTY
PVLGLACRGHKRALPVQSTVLALDMKEEAIETLLCYLELHPRHWLELLPYTYAHCHLRCP
GGSAQLQALV--HRCPPLAACWAKWPPKDTSQ-GSSALEFDVVELADSMGWELASVRQAL
HQLKWDPEPKKGAPQGTGVLVEFSELAFHLHSRGDLTDEEKDQICDFLYSRVQAREHKAL
AHLHQMSKAFQSVAFPSCGPCLEQSDEGHSNRVKTLVSYYFEEEEEEE-----EEETMKD
TQDPKPGQTQ-L--QDWEDQVRRDVHQLLSLRPEEKF----SGRAVARIFHGIASPCYPA
QVFGQDRRFWRKYL--------HLDFHALMHLATEELLLRGR------------------
-----------------------------------------------------------

------------------------------------------------------------
-----------------LPVAVEEAPESHCWGPHLNRAATHSPQHT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRSSSKT-PTPNP-------PGTGPVPTF-
AE-----KVSDEPPQPPGPQSRPGQLQHLQASLSQQLASLDLDWLQRCHSEIPDFLGAPK
ACRPG-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSPDPEASALQEVSIRAGSPQPSSSRGKKQRRNKELWG-SPAQ---------------
VQQQSSQAGPPSEGAGAVALEEDPPGEPVQAQPPQPCSSLSTPRYHRCSTSSQARA--GK
AEGTAHLHI-SRLARHDRGNYVRLNMKQKRYVQGRALRGRLLRKQAWKQKWRKKGECFGG
GGATV-TIKESCFLNEQFDHWAPQ---CPQPV----------------------------
------------SE--EDTDPAGPEPLVP---APQPVPGVPGL-ASTMLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKVR-A
AQVHVLMLTPEALV-----GAGGLSPATQLPPVAFACIDEVHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASEVAQHLAVNEEPGLRG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHAAQ-
------GPGPGGRAPKTTAEAYHAGMCGRERQRVQQAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHANGTDFLAV
KRLVQRVFPACT--CTRPSPEQEGTMGGER-----------PVPKYSSQEAEELGVHQAA
PGPRRTCVGHERALPVQLTVQALDMPEEAIETLLCYLELHPRHWLELLATTYIHCRLSCP
GGSAQLQALA--HRCPPLAVCLAQQLPKDPRQ-GSSSVEFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRRTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVRARERQAL
ARLRRTFQAFHSIAFPSCGPCLEQQDEERSTRLKDLLGRYFEEVEEEA----QGPGDMED
TQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------NLSFHALVRLATEELLRVAC------------------
-----------------------------------------------------------

-------MERLR

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 73)

DVRERLQAWERAFRRQRGRRPSQEDVES-APEETRALYREYR-TLKRT
TGQAGG-GPRSSE---SLPAAAEEAPEPRCWGPHLNRAATKSPQPT-PGRSC-QGSVPDY
GQRLKANLKGTL-----QAGPALGRRPWPLGRASSKA-STPKP-------PGTGPVPSF-
AE-----KVSDEPPQLSEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPK
ACRPD-LGSEESQ-----LLIPGESAV--LGPGA--------------------------
--GSQGPEASALQEVSIRVGSPQPSSSGGEKRRWNEEPWE-SPAQ---------------
VQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPSSQARA--GK
AEGTAPLHIFPRLARHDRGNYIRLNMKRKHYVRGQALRSRLLRKQAWKQKWRKKGECFGG
GGATV-TTKESCFLNEQFDHWAAQ---CPLPA----------------------------
------------SE--KDTDPVGPEPLVP---SPQPVPEVPSL-DPTVLPLYSLGPSGQL
A---------ETPAEVFQALEQLGHQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYSRRSPCLTLVVSPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKIR-A
AQVHVLMLTPEALV-----GAGGLPPAAQLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVAEEPDLHG-PAP
VPTNLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 986)

QALLTLLQGKRFRNLDSIIIYCNRREDTERIAALLRTCLHADW-
------VPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATMAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLRPQGEDLRELRRHVHADSTDFLAV
KRLVQRVFPACTCTCTRPPSEQEGAVGGER-----------PVPKYPPQEAEQLG-HQAA
PGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCP
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGQ-GSSSVKFDMVKLVDSMGWELASVRRAL
CQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQAL
ARLRRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLGRYFEEE--EG----QEPGGMED
AQGPEPGQAR-L--QDWEDQVRCDIRQFLSLRPEEKF----SSRAVARIFHGIGSPCYPA
QVYGQDRRFWRKYL--------HLSFHALVGLATEELLRVAR------------------
-----------------------------------------------------------

-------MERLL

PF11719 // ENSGT00550000074520_1_Domain_0 (13, 59)

DLRERLQAWERAFRQQHGRRPSQDDVKA-APEETRALYREYRTLKRTV
RPSGGG-GGPCSPE--LLPAAAGEAPEPHCWGPHLNRAATQSPQPT-PGRSC-QGSFQDY
GQRLKANLKGTL-----QASPDLGHRPWPLGRSSSKT-PTPKL-------PGTGPAPTF-
AE-----KVSDTPPQPSGLRPRPGRLQHLRASLSVRLGSLDPGWLQRCHSGVPDILGAPK
PCRSG-LGLEESQ-----LLTAGESAV--LGPGA--------------------------
--GSQGPEASALQEVSIGAGNPQPSGSRGEKRRRNEVPWG-SPTQ---------------
VQQQSSQAGPPSETAEAIALEEDSPGEPVQEQPPQPCSSRSTPRYHRLSPSSQARA--EK
AEGIAHLHIFPRLAGYDRGNYIRLNMKQKRYVRGRVLRGRLLRKQAWKQKWQKKGECFGS
GDATF-TIKDSCFLNGRFDHRAPQ---CPQPG----------------------------
------------NE--EDTDPAWSEPLVP---VPQPVPEVPGL-APTVLPLYSLGPSGQV
A---------ETPAEVFHALEQLGHRAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 819)

PGQERAVMRILSGISTLLVLPTGAGKSLCYQ
LPALLYAQRSPCLTLVISPLLSLMDDQ-VSGLPPCLKAACIHSGMTRKQRESVLQKIQ-A
GQVHMLLLTPEALV-----GAGGLPPATKLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCRV------------LRERMGVHCFLGLTATATRRT

ENSGT00550000074520_1_Linker_2_3 (819, 857)

ASDVAQHLAVAEEPGLHG-PAP
VPANLHLSVSMDRDTD

PF00271 // ENSGT00550000074520_1_Domain_3 (857, 985)

QALLTLLQGKRFRNLDSIIIYCNRREDTERVAALLRTCLHPAQ-
------GPGPKGRAPKTMAEAYHAGMCSRERQRVQRAFMQGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDRQPAHCHLFLQPQGEDLRELRRHVHANGMDFWAV
KRLVQRVFPSCT--CARLLPEKEGARGGEM-----------PVAGSPPQEMEQLGSCQAT
PGPRRACVGHERALPVQATVQALDMPQEAIETLLCYLELHPRHWLELLATTYTHCRLYCS
GGPAQLQALA--HRCPPLAVCLAQRLPEDPGK-GSSSVEFDMVELVDSMGWELACVRRAL
CQLQWDHEPQTGMWQSTGVLVEFRELAFHLRSPGDLTAEEKDQICDFLYGRVQAREHQAL
AHLHRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLSRYFEEVEEEA----QGPGGMGD
TQGPAPGQAR-L--QDWEDQVRCDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
QVFGQDRRFWRKYL--------HLSFHTLVRLATEELLQVGRS-----------------
-----------------------------------------------------------

-------MERLRDVRTRLQEWERAFRQQRGRKPGQEDVAA-APEETRALYREYR-ALKGA
LRHAVS-GP------SSLPAAAEEVSEPSCWGTHLNRAATQSPGPT-PDPG--QKSLQDY
GKRLKANLKGALQXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX-------XXXXXXXXX-
XX-----XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX
XXX-X-XXXXXXX-----XXXXXXXXX--XXXXX--------------------------
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX---------------
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX
XXXXXXXXXXXXXXXXXXXXXXXXXMKRKCYVRGLALPGRFFSKLMWKQKWQKKEEYLGR
RQPRS-TDG

PF00098 // ENSGT00550000074520_1_Domain_1 (490, 507)

NCCFQCGKLGHWASQCS

ENSGT00550000074520_1_Linker_1_2 (507, 629)

QPAD------------------------------
---------------EEGTELMGPKLSVP---MEQPVPEAPCP-PPAVPPLYPLGPSGQV
A---------ETPVEVFQALEHLGHQTF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 822)

RPGQEQVIMRILSGVSTLLVLPTGAGKSLCYQ
LPALLYARRSSCLTLVVSPLLSLMDDQ-VSGLPPGLKAACLHSGMTRKQRDSVLQKVQ-A
AQVHVLLLSPEALVGAGD--------LPQLPPIAFACLDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERLGVRCFLGLTATATRSTARD

ENSGT00550000074520_1_Linker_2_3 (822, 908)

VAHHLGIAEDPSLRE-SAA
IPSNLHLSVSMDRDPDQALVTLLQSDRFRTLNSVIVYCNRREDTERVAALLRTCLRGDR-
------G

PF00271 // ENSGT00550000074520_1_Domain_3 (908, 987)

PGSRG---EAVAEAYHAGMCARERRRVQRAFMEGRLLVVVATVAFGMGLDRPD
VRAVLHLGLPASLESYVQAVGRAGRDRQPAQCHLFLQPQGEDLRELRRHVHAQALDFLTV
KRLVQHAFPPCSCP--RPTPDQEGARGGVR-----------LVPRCSSAEN-------EQ
PSQATPCPGHRRALPVEQMVQALDLPEEAIETLLTYLELHPQHWLELLTPTYAHCCLRCP
GGSTQLQALA--QRCPPLAVHLARQPPEDTDG-RHVSVEFDVVELADSMGWELGPVRRAL
HQLQWNPATRTGAPQGNRMLLEFQELAFHLHSPGDLTAEERDQICSFLYGRVQAREREAL
ARLRRTFQIFHSVAFPSCGPCLEQPDEERSARLKAMLSLYFEEEEK-------GPANLEQ
EQGLEPGQVT--------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------

------------------------------------------------------------
-----------------------QALEPSCWGSHLNRAATQSPHPT-PGPSP-QASVQDY
GKRLKANLKGAL-----QAGPALGHTRRPPRRPSSKM-LSSGL-------PAAGAALIA-
PE-----EVSEVPPQALKPQLRPGRLQQLRASLSLRLNSLDPGWLQRCHNEAPDFQGAPE
ACHPG-LDTDLSQ-----PLTLSVPS---VGPST-----GPEA-----------------
--PLPAPEAPTLQAVRVSAGSPQPSNTRGKKRRRSEEPGG-SPAQ---------------
AQQDSSQPELPPEGAGATAHAEGCLGEPVQAQLPSIPAAP-----------SPA-R--WE
ASGMAHLCVLSRPAIQDRGNYVRLNLKQKRYARGPALRGRLLRKQVWKQKWQKKGERFGG
GKLRA-TVKDSCFWCGQLGHWASQCTHPEP--TLA-----SQKEGGEDEGDTQTLPTLEE
VAQQPGTAYCQLPG-KEDTEPAGPELLAP---TQQPVPRAPSP-PPTMPPLYLREPSGQV
A---------ETPAEVFQALEQLGYQAFR

PF00270 // ENSGT00550000074520_1_Domain_2 (630, 817)

PGQEQAVMRILSGMSTLLVLPTGAGKSLCYQ
LPALLYARRSPCLTLVISPLLSLMDDQ-VSGLPPGLKATCIHSGMTRKQRDTALRKVR-A
AQVHVLMLSPEALAGAGEGGPACLT---QLPPVAFACIDEAHCL----SQWSHNFRPCYL
RVCKV------------LRERMGVHCFLGLTATATR

ENSGT00550000074520_1_Linker_2_3 (817, 919)

STARDVAWHLGVAEEAVLRGP-VT
IPANLHLSVSMDRDPDQALVTLLQSERFRALDSVIVYCNRREDTERVAALLRTCLREAW-
------APGPGGRAPEAV

PF00271 // ENSGT00550000074520_1_Domain_3 (919, 987)

AEAYHAGMCSRERRRVQRAFMEGQLRVVVATVAFGMGLDRPD
VRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQAQGEDLRELRRHVHAKTTDFCAV
KKLVQRAFPPCTCSHTQRSPEEEGDHSQER----------------------GL---ARA
PVTITRCPGHKRALPVQPTVQALDMPEEAIETLLCYLELHPQHWLELLAPTYAHCHLRCP
GGPTQLQALT--HRCPPLAVCLAQQPPENTGQ-GSSSVEFDVVQLADSMGWELVPVRRAL
HQLQWDPEPKTGAPRGTGVLVEFRELAFHLHSPGDLTAQEKDQICDFLYSRVQDREREAL
ACLHHTFRAFHSVAFPSCGPCLEQPDEERSARLKAVLSHYFEEEGGE------GPRGTEA
EQGPEPGLAR-L--QDWEDQTRRDIRHLLSSWPEQQF----SGRAVARIFHGIGSPCYPA
QVYGRDRRFWRKYL--------HLSFHALAHLATEEILLWGR------------------
-----------------------------------------------------------

-------MERLRAVRTRLLTWERDFRRRHGRRPGQADVAV-APEETQALYREYA--LKQV
LGQADGSWLPDSEQ---TPEAAQEXXXXXXXXXXXX------------------------
---XXXXXXXXX------X----X-----------------XX-------XXXXXXXXX-
XX-----XXXXXXXXXXXPQPRPAWLQQLQSPLSRRLASLDPGWLQRCQDGSPELLEATD
ACGPG-LSSEEPGKEPQLPQTSGVLAT--LGN----------------------------
--TGPDPEGPTLQEAGGNKGNPRPSKTPTPG--W--DPQG-APPQ---------------
TQWDQDHVRPWLKDAGATELNEDALE----DQSPRPRISSSTPRYHTPTPSTPVSGLLQV
ESDVETLLVSPRSTFQERGNYVKLNLKQKRYARGPALRGAHLRKQVRKQSGRRRRVCFRS
SYSGT-PAQDS-ASLGHSRHWASQSPQSXXXXXX------X-XXXXXX------------
----------------X-X-------------XXXXXXXXXXXPAPMVPPLYPPGPSKQV
A---------ETPPEVLQALRQLGHQAF

PF00270 // ENSGT00550000074520_1_Domain_2 (629, 775)

RPWQEQAVMRVLSGISTLLVLPTGTGKSLCYQ
LPALLYARRSPCLTLVISPLVALMDDQ-VLGLPPGLKAACLHSGLNRKQRESVLQKAR-T
AQVHLLLLSPEAVVGAGSGGATCLPQASQLPPVPFACID-AHCL----SQWXXX

ENSGT00550000074520_1_Linker_2_3 (775, 916)

XXXXXX
XXXXX------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRREDTERTAARLRTALQE---
------SPRPRGVGT

PF00271 // ENSGT00550000074520_1_Domain_3 (916, 987)

EKVAQAYHAGMCIQERRRVQKAFMQGQLRVVVATVAFGMGLDRPG
VRAVVHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRKHVHADAVDFLAV
KRLVQQVFSACSCASPPQEQARAGXXXXXX-----------XX-----XXXXXXXXXXXX
XXXXXXXXXHTRALLIQPAEQALDMPQEAIQTLLCYLELHPQRWLELLPPTYAQCRVHCP
SGPAQLRALA--LSCPPLAAGLDRRVAGDSEW-GCSSVEFNVVELADAMSWELAPVRRAL
RQLQWDQEPRAGTPRSTGVLVEFGELAFHLRCRGDLTPEEKDQLCEFLHGRVCTREREAL
ARLRCTAQAFRSVAFPSCGPCLEQPSAEQSTRLKALVERYFQEEEEEE-----EMLGSGD
LEGPEPGQDR-L--QDWEDQIRRDIRQLLSLRPEEKF----SGRAVARIFHGIGSPCYPA
LVFGHDRRFWRKYL--------HVSFHALMRVATEELLLWSH------------------
-----------------------------------------------------------