Query Results 

------------------------------------------------------------
---------------MAIAASILGCHYGSFVWQLRMMDQARSAFSTLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDNNMRD-NGASVTKPKRFNGFICYGTIAIIL-FFLIG
FMIGYLGYCKRVEAKSECERPAGTESLEV---EGTEPSETEEYFPEAPSHLFWSDLKTML
SEKLSNTEFTSTIRQLNENSYFPREAGSQKDESLAFFIENRFRELQLSKAWHDEHFVKVQ
VKGS---ASNSVTIVG--TNSGMVYLVESPEGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGRLVHANFGTKKDFENL
N---SPVNGSLVIVRAGKITFAEKVANAESFNAIGVLIYMDQA-KFPITN----AEIPFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRATAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
AWETDSS-CRLETS-----RNWNVKLSVNNVLKEIRIF

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NVFG-VIKG----------FEE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLELARILSDMVLKGGFKPSRSIVFASWTAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYSLIEKVM-KDVKHP
VTGQ-SLYR--DS-NWINKVEKFSLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
VYEK

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIQ----KVPQLNKMARAAAEVAGQLIMKLTYDLELNLNYEMYNDKILSFVRDVSR
FRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LNLQWLYSARGDFFRATSRLTTDYRNAERTNRFIMRDINDRIMRVEYHFLS
PYVSPRESP----FRHIFWGTGSHTLSALLEHLKLRQENISAFNETLFRNQLALTTWTIQ
GAANALSGDIWDIDNEL--------

------------------------------------------------------------
---------------------MLGDEQGSFVWQFGMMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENADNNTKA----NGTKPKRCGGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPEEDFPAAP-RLYWDDLKKKL
SEKLDATDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSK

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 407)

AATVTGKLVHANFGTKKDFEGL
D---SPVNGSVVIVRAGKITFAEKVANAESLNAIGVLIYMDRT-KF

ENSGT00550000074421_2_Linker_0_1 (407, 544)

PIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFG--NMEG-DCPS
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKILNIFG-VIKG----------FVE
PDH

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 712)

YVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TD

ENSGT00550000074421_2_Linker_1_2 (712, 789)

YPYLGTSMD
TYKELVE----RIPELNKVARAAAEVAGQFVIKLTHDIELNLDYERYNSQLLLFLRDLNQ
YRADVKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGAHTLSALLENLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAISNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENTDNNMKA----SVRKHRRLNGRLCFGTIAVVI-FFLIG
FMIGYLGYCKRTEQK-DCVRLAETETGNS---EIIQ-----EENIPQSSRLYWADLKKLL
SEKLDAIEFTDTIKQLSQT---SREAGSQKDENLAYYIENQFRDFKLSKVWRDEHYVKIQ
VKGSA--AQNAVTIIN--VNGD-SDLVENPGGYVAYSKATT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VSGKLIHANFGTKKDFEDL
K---YPVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDQT-KFPVVE----AELSLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRKAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFQ--NMET-NCPP
SWNTDSL-CKLESS-----QGINVNLSVNNVLKETRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 732)

NIFG-VIKG----------FEE
PDRYIVVGAQRDAWGPGAA-KSSVGTGLLLKLAQAFSDMVSRGGFKPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTRNFKVSASPLLYTLIEKTM-QDVRHP
IDGK-PLYR--DS-NWISKVEDLSLDNAAFPFLAYSGIPAVSFWFCEN-EDYPYLDTNLD
TYEKLIQ----

ENSGT00550000074421_2_Linker_1_2 (732, 790)

KVPQLNKMVRAAAEVAGQFIIKLTHDIELNLDYDMYNNKILSFVKELNQ
FRADIKAMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAEKTNRFVVREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLTALVENLKLRQKNSSAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----SVAKRKRCNGSIFYGTVAVII-FFVIG
FMIGYLGYCKHVEPKTECQTLAGTESP-----AV---ENPEENVPVVP-QLYWDDLKKKL
SEKLDTTDFTNTIMLLNENPYVPREAGSQKDENLAWYIENQFREYKLSKVWRDEHFVKIQ
VKDS---AQNSVTITG--TNSEFVYLVENPGGYVAYSQSAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTEKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAKSSNAIGVLIYMDKT-KFPIVN----ADVSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAER

ENSGT00550000074421_2_Linker_0_1 (467, 583)

LFE--NMEG-DCPP
DWRTDSS-CRMVTS-----QNKSVKLSVSNVMKEIKILNIFG-VIKG----------FVE
PD----------------------------------------

PF04389 // ENSGT00550000074421_2_Domain_1 (583, 725)

-GFRPSRSIVFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYALIEKTM-QEVKHP
VTGL-SLYQ--DS-NWASKVEKLTFDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----KIPQLNKVARAAAEVAGQFMIKLTHDVELNLDYERYNSELLSFLRNLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFKNSEKTDRFVMKELNDRIMKVEYYFLS
PYVSPRESP----FRHIFWGSGSHTLTALLENLRLRKTNNRAFNETLFRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARATFSNLFGGEPLSYTRFSL
ARHVDGDNSHVEMKLAADEEENADNNMRA----HVKTPRRCTGSICYGAIAVTI-FFLIG
FMIGYLGYCRRVEPKGECERPVDT-EMKG---SEDQELEE-EVVLETPVRLYWDDLKTML
SEKLNPAKFGSTVKQLNQNTYTPREAGSAKDENLAYFVENQFNEYKLSKVWRNEHYVKIQ
VKSST--TPNSVILTS--TNNDLVYLVENPEGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 464)

VTGKLVHANFGTKEDFENL
N---TSVNGSLVIVRAGKITFAEKVANAESLNALGVLIYLDWTK-FPIPK----ADLPVF
GHVHLGTGDPYTPGFPSFNHTQFPPSQSSGLPTIPVQTISRQG

ENSGT00550000074421_2_Linker_0_1 (464, 519)

AEKLFA--NMEG-ECPV
SWRTDSS-CRLQSK-----QNGNVKLTVNNELKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 727)

NIFG-VIKG----------VEE
PDRYVVVGAQRDSWGPGAA-KASVGTALLLELARTFSDMVLNGGFKPCRSIIFVSWSAGD
FGAVGATEWLEGYITSLHLKVVTYINLDKAVLGTTNFKVTGSPMLFKLIEKTM-QEVKHP
LTGM-SLYK--DS-NWVNKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-TDYPYLSTTLD
TYDTLMR----EIPQLNKLMYGAAEVAGQFLIKLTHDFELNLDYEMYNNKMLSFLKELMQ
YKGDVKEMGLSLQWLYSARGDFFRATSRLMTDFHNAERTNRFIMKELNDRIMKMEYHFLS
PYVSPKEFP----FRHIFWGSGPHTLQALLENLKLRKENKAAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------AMDHARAAISNLFSGEPMSYTRFSI
ARQTDGDNSHVEMKLSADDEEGGEAGRPEHLHAHVAQPWRNGKNLCFLLIAAFLLLLIVG
FLIGYLSYRGRMQLAAKCLEGGGKCEVTPTASYLADGDETEEEEVPGPPILYWPDLKNLL
STKLSDRRLEENLRQR-A-NKNSFEAGQSEDENMAIYIHDLFKSFFLNQVWKDKHYIKLQ
VKGST---KNKVSVVE----DGKEEELETPDAYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SETGTVTGKPVYANYGQKEDFQKL
EKSAIELNGTIVIVRAGKITLAEKVVNAKEKGAVGVLMYLDPY---KNT-----DDLVPF
GHAHLGTGDPYTPGFPSFNHTQFPPIESSGLPHIAVQTISSHAASRLFS--KMDGESCLP
QWRGGLLVCKMTVRS---DKQLTVKLEVNNVMVDRKILNIFG-AITG----------FEE
PDRYVVIGAQRDSWGPGAA-KAGVGTAILLELARVISDIVKNEGYKPRRSIIFASWSAGD
YGAVGATEWLEGYSATLHAKAFTYINLDAAVLGTNDIKISASPLLYALLERTM-KGVNDP
LISSRKLYDKVGS-SWVKSIVPFGLDNAAFPFLAYSGIPVVSFGFYNKDEDYPFLGTTQD
TVENLKA-----INSLYAHLRAAAEVAGQIALRLTHDHELFLDFGRYSEELLAF

PF04253 // ENSGT00550000074421_2_Domain_2 (775, 909)

QEKFLV
YDQDVKELGLNLDWLFLARGDFQRAANALRRDIENSDKENKVIRRALNDRIMKVEYDFLS
PFLSPKDAP----LRHIFFGKGSHTLQSLLDHLQLLKTSRSKVDLNMLKEQLALATWTIK
GAANALEGDIWNTDNTF--------

------------------------------------------------------------
-----------------------------------IMDQARSAISNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNMKA----NVRKPRKFNGRLCYAAIAIVI-FFLIG
FMVGYLGYCKRGGQK-DCLRPEDAETDSS---QSFQ----PEEEVPQPSRLFWADLKKML
SEKLDTIEFTDTIRQLSQNTYTPREAGSQKDENLAYYIENQFHDFKLSKVWRDEHYVKIQ
VKGSI--AQNSVSL-N--ESGH-LNLLENPEGYVAYSKAAE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
K---YAVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRT-KFPIVK----ADVPLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPTIPVQTISRETAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFQ--NMEG-NCPS
NWNIDSS-CRLELT-----QNKNVKLAVNNALKETRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 732)

NIFG-VIKG----------FEE
PDRYIVVGAQRDAWGPGAA-KSSVGTGLLLRLAQVFSDMVSRGGFKPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLIGKTM-QDVKHP
INGK-SLYQ--DS-NWINKVEPLSLDNAALPFLAYSGIPAVSFCFCED-EDYPYLGTTLD
TYDQLIA----

ENSGT00550000074421_2_Linker_1_2 (732, 790)

KVPQLNKMVRAAAEVAGQFIIKLTHEIELNLDYEMYNNKILAFVKDLNQ
FRADIKAMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPREFP----FRHIFFGSGSHTLPALVENLKLRQRNISAFDETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENTDNNTKP----NGTKPKRCGGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----AR---EEPEEDFPAAP-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----RIPELNKVARAAAEVAGQFVIKLTHDTELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKRDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEESADNNTKA----NVTKPKRCNGSIFYGTIAVII-FFVIG
FMIGYLGYCKHVEPKIECQRLAGTESP-----AV---ENPEENLPVVP-QLYWDDLKKML
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLAWYIENQFRECKLSKVWRDEHFVKIQ
VKDS---AQNSVTITG--TNSEFVYLVENPGGYVAYSQNAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTEKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESANAIGVLIYMDKT-KFPIVD----ADVSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAER

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFE--NMEG-DCPS
DWKTDSS-CRMVTS-----QNKSVKLSVSNVMKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDRYVVVGAQRDSWGPGAA-KSSVGTALLLELAQTFSDMVLKDGFQPSRSIVFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTFINLDKAVLGTSNFRVSASPLLYALIEKTM-QEVKHP
VTGL-SLYQ--DS-NWASKVEKLTFDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----KIPQLNKVARAAAEVAGQFMIKLTHDVELNLDYERYNSQLLSFLRNLNQ
YRADIREMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFKNSEKTDRFVMKELNDRVMKVEYYFLS
PYVSPRESP----FRHIFWGSGSHTLSALLEHLKLRKTNNRAFNETLFRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

MRHPLDPSRHLQSGAFFLQPHQLPRSSQGLPTPVRAHSWPRGRPFPEVYVRQEVTQSPGG
RRGRDQAINGCWGGGHPTRGCQHLPAAGSFVWQLRMMDQARSAFSSLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDSNTRS-NHIGVAKPKRLNGYVCYGIIAVIT-FFLIG
FMIGYLAYCKRVESKTDCKTLVPTEPSET---EETETFEAE-NFPQTP-RLFWADLKILL
SKGLDTTDFTRTIKMLNE-DYAPREAGSQKDESLGFFIENQFREFKLSKVWHDEHFVKIQ
VKGSN--AENSVTLVN-TDSNSLVYPVESPEGYVAYSKATT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 466)

VTGKLIFANFGTKKDFEDL
K---MPVNGSLVIVRAGKITFAEKVANAQSLDAIGVLIYMDRA-NFPIIN----ADVPVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAE

ENSGT00550000074421_2_Linker_0_1 (466, 519)

KLFG--NMEQ-DCPL
TWRTDFP-CKLVSS-----PSKNVKLTVNNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 743)

NIFG-VIKG----------FEE
PDRYVIVGAQRDAWGPGAA-KSSVGTSLLLNLAQILSDMVIKGQFKPSRSIVFASWSAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYSLIEKMM-QDVKNP
VTGQ-SLYR--DS-NWINKVEKLSFDDAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYDVLSK----RVPQLNRMARA

ENSGT00550000074421_2_Linker_1_2 (743, 790)

AAEVAGHLVIKLTIDFELNLNYEMYNDKILSFVREMNQ
FRVDIREMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTSDYRNVETRDKFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVEHLKLRQKNSSAFNQTLLKNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSTLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEESVDNNVRG-NLASVTKPKRFNGFICYGTIAVIV-FFLIG
FMIGYLGYCKRVEPKAECERLSGTESLGI---VGTEPPEREEYAPETSNRFFWTDLKTML
SKRLNDTEFATTIRQLNENPYVPREAGSQKDDSLAFFIENQFRTYPLTRAWHDEHFVKIQ
VKSSS--AQNSVTIVG--TDSGVVYLVESPEGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKAATVTGRLVHANFGTKKDFENL
N---SPVNGSLVIVRAGKITFAEKVANAQSFNASGVLIYMDQS-RFPIVD----AEVPVF
GHAHFGTGDPYTPGFPSFNHTQFPPSQSSGLPGIPVQTISRAAAEKLFE--NMEG-DCPS
AWEIDSS-CRLETS-----RNRNVKLTVNNVLKEIRIFNVFG-VIKG----------FEE
PDRYVVVGAQRDAWGPGAA-KSSIGTALLLELAQIFSDMVSKGGYRPSRSIVFASWSAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTKNFKVSASPLLYSLIEKTM-KDVKHP
VTGQ-SLYQ--DS-NWINKVEEFSLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
NYENLKR----KIPLLNQMARGAAEVAGQLIMKLTYDFKLNLNYEMYNDKI

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFVRDMNR
FRADMKEMGLNLQWLYSARGDFFRATSRLTTDYKNAESTNRFVMREINDRIMKVEYHFLS
PYVSPRDSP----FRHIFWGSGSHTLSALLEHLKLRQKNNSAFNETLLRNQLALATWTIQ
GAANALSGDIWDIDNEL--------

------------------------------------------------------------
------------------------------------MDHARAALSNLFSVEPMSYTRFSI
ARQTDGDNSHVEMKLSADDEEGGDIERPEHMHVSMAQPQRNGKRLCFLVIAAVL-LLLIG
FLIGYLSYRGRMQLAARCQDGSGGCEITPTASYLVDGEGTVEEEIQGPPVIFWPELKAML
SKKLSAKNLVDNLRWR-V-GVDSFEAGEAEDTNMATYIHEEFRN-FLDKVWNDEHYIKLQ
VRGST---KNQVSISI----NGKEEILETPDAYVAYSESGS

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 403)

VSGKPVYVNYGLKKDFEII
QKVVASLNGTIVIVRAGKITLAEKVANAKEAGAAGVLMYVDS

ENSGT00550000074421_2_Linker_0_1 (403, 519)

L-MYGIT-----DTLIPF
GHAHLGTGDPYTPGFPSFNHTQFPPVESSGLPHIAVQTISSSAAARLFS--KMDGDTCSE
GWKGAIHSCKVTTKH---ESQIMVKLDVNNSMKDRKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 727)

NIFG-AIQG----------FEE
PDRYVVIGAQRDSWGPGVA-KAGTGTAILLELARVISDIVKNEGYKPRRSIIFASWSAGD
YGAVGATEWLEGYSAMLHAKAFTYISLDAPVLGASHVKISASPLLYMLLGSIM-KGVKNP
AAVSESLYNRLGP-DWVKAVVPLGLDNAAFPFLAYSGIPVLSFGFYNKDEEYHFLDTKGD
TLENLR

ENSGT00550000074421_2_Linker_1_2 (727, 791)

K-----IDNLDALLAAAAEVAGQAALRLTHDHELFLDIGRYSEELLAYQEEFLP
YIKEVRELGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 864)

TLDWLFFARGDFQRAVTALRRDIANSDGENRVIRRALNDRMMKVEYDFLS
PYLSPKDVP----FRHIFFGKGPHTLRSLVEHLQLLKTNRSSVDLNLLREQLALATWTIK
GRPMPWE-----VISGILTMNSRHC

------------------------------------------------------------
-----------------------------------MMDQARSALSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEDENTDNNMRA----NVTKPKRFNGSICYSSIAVII-FFLIG
FMIGYLGYCKRVEPKAECERLAGTESS-----VM---EEPNEDFPEIP-RLFWADLKTKL
SEKLDTTEFTSTIKLLNENSYVPREAGSQKDENLAMYVENQFRGFKLSKVWRDEHFVKIQ
VKGS---AQNSVTIVG--TGGEFVYLVENPEGYVAYSKATT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
Q---VPVNGSVVIVRAGKITFAEKVANAESFNAIGVLIYMDQA-KFPIVN----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFE--NMEG-DCPF
GWRTDSS-CKLVSA-----QNRSVKLVVKNVQKEIKIF

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 726)

NIFG-VIKG----------FVE
PDRYIVVGAQRDAWGPGAA-KSSVGTALLLKLAQIISNMVLTDGFQPSRSIIFASWSAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTNNFKVSASPLLYTLIEKTM-QEVKHP
VTGL-SLYQ--DS-NWISKVEKLSFDNAAFPFLAYAGIPAVSFCFCED-TNYPYLGTTMD
TYEEL

ENSGT00550000074421_2_Linker_1_2 (726, 790)

IK----KIPQLNKVARAAAEVAGQFIIKLTHDVELNLDYEMYNNKILAFVRDLNQ
FRSDIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSKLTTDFKNAERTNRFVMREINDRIMRVEYYFLS
PYVSPRESP----FRHIFWGFGSHTLSALVENLKLRQENNGAFNETLLRNQLALATWTLQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
----------------------------------------MPFSPKQFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENTDNNTKA----NGTKPKRCGGNICYGTIAVIL-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----AR---EEPEEDFPAAP-RLYWDDLKKKL
SEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVN--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDRT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----RIPELNKVARAAAEVAGQFVIKLTQDIELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENVENNVRA----NVAKPKRCNGTLCYAMVAIII-FFLIG
FMIGYLGNCKRVEQKAECESVAGTEVEQS---EN---AEPEEDLPVIPPRLYWEDLRTML
SEKLDTTDFTSTIRQLNENSYIPREAGSQNDENLASFVENKFRDFKLSKVWHDEHFVKIQ
VKDS---AQNSVIIVN--KNSEAPDLVENPMGYVAYS

PF02225 // ENSGT00550000074421_2_Domain_0 (338, 421)

KATTVTGKLIHANFGTKKDFEDL
N---SPVNGSIVIVRAGEITFAEKVANAESLNAIGMLIYMDQM-KFPIVK----ADLPLF

ENSGT00550000074421_2_Linker_0_1 (421, 544)

GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISREAAEKLFG--NMEG-ACPS
EWQTDST-CRLQSS-----QNKNVKLTVNNVLKEARILNVFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 707)

YIVVGAQRDAWGPGAA-KSSVGTALLLELARMFSDMVLKGGFKPSRSIIFASWSAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTTNFKVSASPLLYKLIEKTM-QDVKHP
VTGM-SLYQ--DS-NWVNKVEKLSFDNAAFPFLADSGIPSLSFWFC

ENSGT00550000074421_2_Linker_1_2 (707, 789)

ED-TDYPYLGTTFD
TYGMLIQ----KIPQLNKMARAAAEVAGQFMIKLTHDAELNLDYEMYNNKILSFVRELNQ
YRAYIKEL

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLNLQWLYSARGDFFRATSRLTTDFKNAEITNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALLENLNLRQKNNGAFNETLLRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARSAFSNLFSGQSLSYTRFSL
ARQVDGSNSHVEMKIAADEEENADNTMGS-NPANVTKPRRLNSSICYGVIAIII-FFLIG
FMIGYLGYCKRAEPKAGCEGESATAPSAT---EDPEAPEA-DEFPEAPSYLFWGDLKKIL
SQKLNTAEFASTIKRLSESPYVPREAGSEKDENLGYFIENRFREFKLSKVWRDEHYVKTQ
VKASV--ENS-VSIVA--GNGTIVSLVEHPKGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKPATVTGKLVHANFGTITDFENL
N---SPVDGSLVIVRAGKITFAEKTANAESFNATGVLIYMDQA-DFPVVE----ADLPVF
GHAHLGTGDPYTPGFPSFNHTQFPPAQSSGLPNIPVQTISRSGAEQLFDPKNMEQ-LCPG
TWKTKSL-CKMRSV-----EGRNVKLTVNNVLKEARILNIFG-VIKG----------FEE
PDRYVVVGAQRDAWGTGAA-KSGVGTALLLELARIFSDMVLKDGFKPSRSIVFASWSAGE
FGAVGATEWLEGYLSTLHLKAFTYINLDKAVLGTSNFKVSASPLLYLLIEKTM-QDVKHP
ISGQ-SLYQ--DS-NWANKVEKLSYDDAAFPFLAYSGIPALSFCFCED-NDYPYLGTQKD
TYEVLVE----RIPQLDKMARTAAEVAGQLVIRLTLGLELDLDYERYNDKM

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFLKDINQ
FRTDVKEMGLNLQWLYSARGDFFRATSRLTTDFKNAERTNKIIMREMNDRIMKVEYHFLS
PYVSPKDYP----FRHIFWGSGSHTLSALLENLELRQKNRAAFNETLLRNQLALTTWTIQ
GAANALTGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADNNMKA----SVRKPKRFNGRLCFAAIALVI-FFLIG
FMTGYLGYCKRVEQKEECVKLAETEETDK---SETM----ETEDVPTSSRLYWADLKTML
SEKLNSIEFADTIKQLSQNTYTPREAGSQKDENLAYYIENQFHEFKFSKVWRDEHYVKIQ
VKSSI--AQNMVTIVD--SDGN-FESVESPEGYVAFSKPAE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VSGKLVHANFGTKKDFEEL
S---YSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKN-KFPVVE----ADLALF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFR--KMEG-SCPA
RWNIDST-CKLELS-----QNQNVKLTVNNVLKERRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 733)

NIFG-VIKG----------YEE
PDRYVVVGAQRDALGTGVAAKSSVGTGLLLKLAQVFSDMISKDGFTPSRSIIFASWTAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIM-QDVKHP
VDGK-SLYR--DS-NWISKVEKLSFDNAAYPFLAYSGIPAVSFYFCED-ADYPYLGTRLD
TYEALTQ----K

ENSGT00550000074421_2_Linker_1_2 (733, 791)

VPQLNQMVRTAAEVAGQLIIKLTHDIELNLDYETYNSKLLSFMKDLNQ
FKTDIRDMGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 906)

SLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVENLKLRQKNITAFNETLFRNQLALATWTIQ
GVANALSGDIWNIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSSLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDSNVRG-NHASVTKPKRLNGFICYGTIAVVL-FFLIG
FMIGYLGYCKRVEPKAECERPSGTESLSP---EGTEPSETEEYFPETPSRLFWADLKEKL
LERLHNTEFLTTMRQLNEKTYVPREAGSQKDESLAFFIENQFRAFLLSKIWRDEHFVKIQ
VKSSS--AQNSVTIVG--MDSGVVYLVESPEGYVAYSK

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 420)

AATVTGRLVHANFGTKKDFENL
N---SRVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDQS-RFPIIN----ADTPV

ENSGT00550000074421_2_Linker_0_1 (420, 544)

F
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAADKLFE--NMEG-DCPS
AWETDSS-CRLETS-----QNRNVKLTVNNVLKEIRIFNVFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 725)

YVVIGAQRDAWGPGAA-KSSVGTTLLLELAQIFSDMVLKDGFRPSRSIVFASWSAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTNNFKVSASPLLYSLIEKTM-KDVKHP
VTGQ-SLYR--DS-NWFNKVEEFSLDNAAFPFLAYSGIPAVSFCFCED-TYYPYLGTTMD
VFEE

ENSGT00550000074421_2_Linker_1_2 (725, 789)

LEK----KIPQLSKMARGAAEFAAQLIMKLTYDLELNLNYEMYNDKILSFVRDMNR
FRTDIKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLNLQWLYSARGDFFRATSRLTTDYKNTERTNRYVMRKINDRIMKVEYHFLS
PYVSPRDSP----FRHIFWGSGSHTLSALLEHLKLRQKNNSAFNETLLRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADSNMRA----NVPRRRKCNGSICYGTIAVII-FFLIG
FMIGYLGYCKRGEPKAKCDREAEAESSDV--------EEPEENFPEIP-RLYWADLKTML
SKELDAAQFTSTIEWLNGNSYIPREAGSXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX
XXXXXXXAANSVSVVG--PSNDTIHLVENPGGYVAYSKATTVTXXXXXXXXXXXXXXXXX
X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX----XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXQSSGLPNIPVQTISRAGAEALFK--HMEG-ECPS
GWEIDPS-CRLQSS-----ENKRVKLTVNNVLKEMRIINIFG-VIKG----------FEE
PXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXGFKPSRSIVFASWSAGD
FGAIGATEWLEXXXX-XXXRAFTYINLDKAVLXXXXXXXXXXXXXXXXXXX-XXXXVKNP
TT-S-PLLG--TS-NLTHQSEKLSFDNAAFPFLAYSGIPAVSFCFCED-ADYLYLGTTMD
TYDALVR----AVPQLDQMARAAAEVAGQLMIKLTHEIELNLDYEMYNNEI

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFVRGLNQ
FRADIKEMGLNLQWLYSARGDFFRATSRLTTDFHNTEITNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGCGSHTLSALLDNLKLRQRNSGAFNETLLRNQLALATWTIQ
GAANALSGDVWDVDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSTLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDNNMRG-NHASVPKPKRCNGFICYGTIAVVL-FFLIG
FMIGYLGYCKRVEPKAECERPTGTEALGT---EGTEPSETEEYFPETPSRLFWTDLKTML
SERLSNTDFTNTMRWLNENSYVPREAGSQKDESLALLIENRFREFQLSKSWRDEHFVKIQ
VKSSN--AQNTVTIVD--MESDLVYLAESPEGYVAYS

PF02225 // ENSGT00550000074421_2_Domain_0 (338, 422)

KATTVTGRLVHVNFGTKKDFENL
K---SPVNGSLVIARAGKITFAEKVANAQSYNALGVLIYMDQA-RFPIVN----ARIPFF
G

ENSGT00550000074421_2_Linker_0_1 (422, 548)

HAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEKLFE--NMEG-DCPS
AWEIDPS-CRLETS-----SNKNVNLTVNNVLKEIRIFNVFG-VIKG----------FEE
PDRYVVI

PF04389 // ENSGT00550000074421_2_Domain_1 (548, 724)

GAQRDAWGPGAA-KSSVGTALLLELARIFSDMVLKGGFKPSRSIVFASWSAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAILGTSNFKVSASPLLYSLLEKTM-KDVKHP
ITGQ-SLYR--DS-NWINKVEKLSLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
LYE

ENSGT00550000074421_2_Linker_1_2 (724, 790)

NLNQ----KIPQLNKMARGAAEVAGQLIMKLTYDLELNLNYEMYNDRILSFVRDMNQ
FRTDIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 908)

LNLQWLYSARGDFFRATSRLTTDYKNAERTNRFVMREINDRIMKVEHNFLS
PYVSPRDSP----FRHIFWGSGSHTLPALVEHLKLRQKNKSAFNETLLRNQLALATWTIQ
GAANALSGDIWDIDNEL--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------VANAESFKAAGVLIYLDRK-DFALVE----AKAAVF
GHAHLGTGDPFTPGFPSFNHTQFPPSKSSGLPNIPAQTISRSAAETLMR--QMDGEQCPQ
QWEGGPT-CKINSLKGQFEMMVFVRATGSNCWTGGLVINIDS-TMDL----------REE
PHR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 725)

YVVVGAQRDAWGPGIA-KSGVGTSLLLNLARTYSDMVLTGGYKPRRSVVFASWSAGE
FGSVGATEWLEGYLSTLHLKAFTYINLDSAVVGDGNFKVSASPMLYTLLEKTM-QEVKYP
-SGS-SLFR--DT-DWVKDVEPLSLDNAAFPFIAYSGIPAVSFSFCG-DKKYPYLGTQLD
TLDN

ENSGT00550000074421_2_Linker_1_2 (725, 789)

L-K----SFPNLNSLMRAAAEVAGQMMIRLTHDHELYLDYVRYNQELLKFIKAFSP
FQQEIKAL

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLSLQWLYSARGDFVRATTALTTDFQNAESENKFITRLINDRIMKVEYYFLS
PYVSPKETP----FRHIFWGSGSHTLSALIEHLDLLKKKDDAFNETLFRNQLALATWTIQ
GVANALAGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----NVTKPKRCGGSICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPEEDFPAAP-RLYWDDLKKKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGRLVYLVENPGGYVAYSK

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 407)

AATVTGKLVHANFGTKKDFEDL
D---TPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KF

ENSGT00550000074421_2_Linker_0_1 (407, 544)

PIVN----AELSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAEKLFG--NMEG-DCPS
DWKTDST-CRMVTS-----ESKNVKLTVSNVLKEIKILNIFG-VIKG----------FVE
PDH

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 712)

YVVVGAQRDAWGPGAA-KSGVGTALLLKLAEMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QNVKHP
VTGQ-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TD

ENSGT00550000074421_2_Linker_1_2 (712, 789)

YPYLGTTMD
TYKELTE----RIPELNKVARAAAEVAGQFMIKLTHDVELNLDYERYNSQLLSFVRDLNQ
YRADIKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FRHVFWGSGSHTLSALLENLKLRKQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----NVTKPKRCSGSICYGTIAVIV-FFLIG
FMIGYLGYCKGVEPKTECERLAGAESP-----VR---EEPGEDFPAAR-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGRLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---TPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVN----AELSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CRMVTS-----ESKNVKLTVSNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QNVKHP
VTGQ-FLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----RIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSFVRDLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FRHVFWGSGSHTLPALLENLKLRKQNNGAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENGDNNMGD-NHANVTKPKRFGGSICYVTIAVII-FFLIG
FMIGYLGYCKRAERKTECERPAATEAGNT---EETYTPDAEDFFPETP-HLFWGDLKTML
SEKLDNTEFTSIIRQLNENVYVPREAGSQKDENLGFFIENKFREYKLSKVWHDEHFVKIQ
VKGST--NQNSVTIVD--AKGDMLFLVENPEGYVAYSK

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 407)

VTTVTGKLVHANFGTKDDFEKL
N---SPVNGSLVIVRAGKITFAEKVANAESLNAAGVLIYMDHV-YF

ENSGT00550000074421_2_Linker_0_1 (407, 544)

PITK----ANLPLF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAGAEKLFE--NMEG-DCPS
AWKTDPL-CKLLSS-----QNKNVKLVVKNVLKETKILNVFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 710)

YVIVGAQRDAWGSGAA-KSSVGTALLLELARIFSEMVLKGGFKPQRSIVFASWSGGE
FGAVGATEWLEGYLSTLHLKAFTYINLDKAVLGTSNFKVSASPLLYSLIEKTM-QDVKHP
VTGQ-ALYW--DS-NWDKKAEKLSFDNAAFPFLAYSGIPAVSFCFCED-

ENSGT00550000074421_2_Linker_1_2 (710, 789)

TEYLYLGTTMD
TFEMLSQ----KVPELNKVVRAVAEVAGQLMIKLTHDIELNLDYEKYNEKLLSFVKDIVQ
FGADIKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLNLQWLYSARGDFFRATAKLTTDFKNAEKGDKFVMREINDRIMKVEYYFLS
PYVSPKDFP----FRHIFWGSGSHTLSALLENLKLRQKNSSAFNDTLLRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENAESNTKA----NVGKPKRCNGSIFYGTIAVII-FFMIG
FMIGYLGYCKHIEPKTECQTLAGTESP-----AM---ENPEENFPVVP-QLYWDDLKKKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLAWYIENQFRECKLSKVWHDEHFVKIQ
VKDS---AQNSVTITG--TNGEFVYLVENPGGYVAYSQNAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTEKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESSNAIGVLIYMDKA-KFPIVN----ADVSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAER

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFE--NMEG-DCPS
DWKTDSS-CRMVTS-----QNKSVKLSVSNVMKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 695)

NIFG-VIKG----------FVE
PDRYVVVGAQRDSWGPGAA-KSSVGTALLLKLAQTFSDMVLKDGFQPSRSIVFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSDFKVSASPLLYTLIEKTM-QEVKHP
VTGL-SLYQ--DS-NWASKVEKLTFDNAAFPFLAYSGIPAVSFCFCEV-SLKNLK-----
---MM-------------------------------------------------------
-SCSVT--QLGVQWPG--HGSLQPQA----------DCVN------HLVLFSQVEYSFLS
PYVSPRDSP----FRHIFWGSGSHTLSALLGHLKLRKTNHRAFNETLFRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAISNLFGGEPLSYTRFSL
TRQADGDHSHVEMKLSADEEEVTENHTQG-HHATVAKPKRWNGYICYGTIAVII-FFLTG
FMVGYLGYCKRAETKASCEPQVAATKTPA---S----QTDDLLEPRAPSRLFWGDLRAML
SDKLTKTDFIKAIKEMN--THVPGLAGSQKDEELAVLLRDRFHTYKLSDVWLDEHFVKLQ
VKGSS---RNSVTILNADSXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXX
X---XXXXXXXXXXXXXXXXXXXXVANAGKLDAAGVLIYMDHS-RFPVVN----ADLALF
GHAHLGTGDPYTPGFPSFNHTQFPPSPSSGLPDLPVQTISRSDAEKLFXXXXXXX-XXXX
XXXXXXX-XXXXXX-----XXXXXXXXXXXXXXXXXXXXXXX--XXX-------------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFRPSRSIVFASWSAGD
FGAVGATEWLEGYLSSLHLKTFTYINLDKAVLGTKNFKVSASPLLYSLIEKTM-QSXXXX
XXXX-XXXX--XX-XXXXXXEKLSIDNAAYPFLAYSGIPAVSFSFCED-TEYPYLDTPMD
SFDLLIQ----QVPLLDNVTRAAAEVAGQLVVKLTHDVELSLDYEAYWQD-

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

PGVVRDMSQ
FRADVKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVEYSFLS
PYASPRESP----FRHIFWGSGSHTLAALLENFKLRQKNSSTVDDTMLKDQLALATWTIQ
GAANSLSGDIWDIDNEL--------

------------------------------------------------------------
------------------------------------MDHARAAISNLFSGEPTSYTRFSI
ARQTDGDNSHVEMNLAADEEEGGEIGRPEHLHASMPPPRRNGKNLCFIIMAAVL-LLLIG
FLIGYLSYRGRMQRVNRCLDGSGNCEMTPTASYFSD-DGMEGEEAPEQRILYWPDLRKML
SSKLSVSSLEANLRQR-E-GKNSFEAGKVEDESAASHIHEQFTSFRLDDVWNDEHYVRLQ
DKGSS---KNQVFIVE----DAQEE-LESPDAYVAYS

PF02225 // ENSGT00550000074421_2_Domain_0 (338, 429)

KSGTVTGKPIYVNYGRKEDFQKI
RNMRVSMNGTIIIFRAGKITLAEKVANARKEGVVGALMYLGPS-KDQKA-----DSYAPF
GHAHLGTG

ENSGT00550000074421_2_Linker_0_1 (429, 544)

DPFTPGFPSFNHTQFPPVESSGLPHIPVQTISRKAATRLFG--KMDGEKCLE
DWTADIMGCKVTVSN---NSKMKVKLTVNNVMVDRKILNIFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 732)

YVVLGAQRDSWGPGAA-KAGVGTAILLELARVISDMVKNDDYKPRRSIIFASWSAGE
YGAVGATEWLEGYSTTLHAKAFTYINLDTAVLGSRDVKISASPLLYSLLEATM-KRVKDP
TNNLGYLYDKAGS-DWIKKVVPLDLDNAAFPFLAYSGIPVVSFGFYNEGDEYAFLGTTED
TLANLKE----

ENSGT00550000074421_2_Linker_1_2 (732, 789)

KTGQLYPLMYAAAEVAGQIALRLTHDHELFLDFDRYSDELLSFQEKLWH
FNANVKEL

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLTLNWLYFARGDFQRAADTLRRDIENSDRENRIVRRALNDRMMKVEYDFLS
PYLSPKDAP----FRHIFFGRGSHTLHSLLENLEQLAVNKTSVDVNELKEQLALATWTIK
GAANALVGDIWNTDNEI--------

------------------------------------------------------------
-----------------------------------MMNQARATFSNLFGGEPLSYTRFSL
ARHMDGDNSHVEMKLAADEDENTDNNMRA----NVKTPRRCSGSICYSAIAVAV-FFLIG
FMIGYLGYCKRVEPKGECERTEATDVMKG---SDDLEQEE-EEIPQLPSRLYWEDLKTML
SKKLDPAKFGSTVKQLNQNTYIPREAGSANDETLAYFIENQFSEYKLSKVWRNEHYVKIQ
VKSST--APNSVTLIETGGKSDMSYLVENPEGFVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKEDFENL
K---TSVNGSLVIVRAGKITFAEKVSNAASLNALGVLIYLDQA-KFPIIK----ADLPVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPTIPVQTISRQAAEQ

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPT
SWRTDHT-CKLQSK-----QNKNVKLTVQNELKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 724)

NIFG-VIKG----------VEE
PDRYVVVGAQRDSWGPGAA-KSSVGTALLLELARTFSDMVLNGGFKPRRSIIFVSWSAGD
FGAIGATEWLEGYITSLHLKVVTYINLDKAVLGSSNFKVTGSPMLYKLIEKTM-QEVKHP
VTGK-SLYK--DS-NWINKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTLD
TYD

ENSGT00550000074421_2_Linker_1_2 (724, 790)

MLLK----KIPELNQLMYAAAEVAGQFVIKLTHDFELNLDYEIYNNKMLSFLRELMK
YRADIKEIG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRAASRLMTDFHNADRTNRFIMKELNDRIMKVEYHFLS
PYVSPRESP----FRHIFWGYGSHTLQALLENLKLHKDNKATFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAISNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENTDNNMKA----SVRKHRRFNGRLCFGTVAVVI-FFLIG
FMIGYLGYCKRVEQK-DCVRLAETEADNS---EISQ-----TEDIPQSFRLYWADLKKLL
SEKLDAIDFTDPIKQLSQT---SREAGSQKDENLAYYIENQFRDFKLSKVWRDEHYVKIQ
VKGSV--AQNSVTIIN--ANGD-SNLVENPEGYVAYSTAAS

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLFHANFGTKKDFEDL
N---YPVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDQT-KFPVVE----AELSLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRKAAEN

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFR--HMEG-NCPP
SWKTDSL-CRMASS-----QDKKVNLSVSNVLKETRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 727)

NIFG-VIKG----------FEE
PDRYIVVGAQRDAWGPGAA-KSSVGTGLLLKLAQAFSDMVSRGGFKPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
IDGR-PLYR--DS-NWINKVEKLSLDNAAFPFLAHSGIPAVSFWFCED-EDYPYLGTNLD
TYEKLI

ENSGT00550000074421_2_Linker_1_2 (727, 790)

Q----KVPQLNKMVRAAAEVAGQFIIKLTHEIELNLDYDMYNNKILSFVKELNQ
FRVDIKAMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLPALVENLKLRRKNSSAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
----------------------MVRAEGSSVWQFRMMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----NVTKPKRCSGSICYGTIAVIV-FFLIG
FMIGYLGYCKGVEPKTQCERLAGTESP-----VR---EEPGEDFPAAR-HLYWDDLKRKL
SEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGSLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
H---TPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVN----AELSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTVSRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CRMVTS-----ESKNVKLTVSNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QNVKHP
VTGQ-FLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----RIPELNKVARAAAEVAGQFMIKLTHDVELNLDYERYNSQLLSFVRDLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FRHVFWGSGSHTLPALLENLKLRKQNNGAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------------------FGGEPSSYTRFSM
ARQMDGDNSLVEMKLAAEDDESAD-NIRN-HPPRATKPKRFRSNLCYGVIAVIL-FFLIG
FMIGYLGYCKRGEPVANCGGVSVGVTTD------------PDESATCPSHLFWGDLKKLL
SQKLDHTEFTSTIEQLN--SYNPREAGSLKEESLALYMERKFQDFQFSKVWRDEHYVKIQ
VKNSI--ASNVVSIVN--GTGTTLSVVENPQGYVAYSKAATVIGKLVHANFGLKEDFEAL
G---PLENDSLVIVRAGKIPFAEKA-NAERFN-AGVLIYLDFA-DVDIAE----AKLSVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPGIPVQTISRFAAEQLFK--NMEQ-DCPS
EWKADSA-CKRKSR-----PDRNVKLTVNNVLKETKILNIFG-VIKG----------IEE
PDRYVVIGAQRDAWGPGAA-KSSVGSALLLELARIISEMVIKDGFKPSRSIVFASWSAGE
FGAVGATEWLEGYLSNLHLKAVTYINLDKAVVGTNNFKVLASPLLYSLIEKTM-QDVKHP
LTGR-LLYR--DS-NWANKVEPFSLDNAAYPFLAYSGIPAVSFCFCED-QEYPFLGTSGD
TYKELIE----RVPQLNKMARAAAEVAGQLVIKLTLDLELNLDYERYNDKL

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFLRDINQ
YRTDIKEMGLSLQWLYSARGDFFRSTSRLTTDLRNVEKANRFIMREMNDRIMKVEYRFLS
PYVSAKESP----FRHIFWGSGSHTLQALLDTLKLRQKNRNAFNETLLRNQLALATWTIQ
GAANVLARDIWEIDNAF--------

------------------------------------------------------------
-----------------------------------MPPTLLIKARSLFSSEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADSNMRA----NAKKPKRFNGRICYGTIAVII-FFLIG
FMIGYLGYCKRVERKEECERLTGMEADES---ENSQ--TEESDFSRLPSRLYWADLKAML
SEKLNDIDFTKTIKQLNQNIYVPREAGSQKDENLAYFIENQFNAFKLSKVWRDEHYVKIQ
VKGST--AQNSVTILD--SKGTMVYLVEHPEGYVAYSKAAE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLIHANFGTKKDFEDL
S---IPVNGSLVIVRAGKIPIAEKVANAQSFNAIGVLIYLDQA-KFPIAK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRKAAET

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFK--NMVG-ECPR
SWNTDSS-CRLQST-----ENGNVKLAVNNVLKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FEE
PDRYIVVGAQRDSWGPGAV-KSSVGTGLLLELARTFSDMVSKGGFRLSRSIIFASWSAGD
FGAVGATEWLEGYLTSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
LDGQ-PLYR--DS-NWNNKVEKLSLDDAAFPFLAHSGIPAVSFCFCED-SDYPYLSTALD
TYDI

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIQ----KIPQLNKIVRAAAEVAGQFIIKLTHDVELNLDYDMYNNKILSFVKDLNQ
FRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVEHLKLRQKNNGAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARATFSNLFGGEPLSYTRFSL
ARHVDGDTSHVEMKLAADEEENAD-SMRA----NAKAPRRCVKSICYGAIAITI-FFLIG
FLIGYLGYCKRIEPKAECESPAVMDAMNG---SEDPEPGDEEFSSEASPRLYWEDLKKML
SEKLSNAKLSDTVKQLNEDAYVPREAGSEKDENLAYFVENQFNEYKLSKVWRNEHYVKIQ
VKNST--APNSVTVTD---AKGLVYLVENPEGYVAYSKAATV

PF02225 // ENSGT00550000074421_2_Domain_0 (343, 467)

IGKLVHANFGTKKDFEDL
N---TSVNGSLVIVRAGEITFAEKVSNAASLNALGVLIYLDNI-KFPITK----ADLPFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPTIPVQTISREAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFR--NMER-ECPS
NWRTELA-CRLQTS-----QERSVKLVVNNVLKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 727)

NIFG-VIKG----------VEE
PDHYVVVGAQRDSWGPGAA-KASVGTALLLELARTVSDMVLKGGFKPHRSIIFVSWSAGD
FGAVGATEWLEGYITSLHLKAVTYINLDKAVLGTTNFKVTGSPMLYKLIEKTM-QEVKHP
LTGA-SLYK--DS-NWVNKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-MDYPYLSTKLD
SYDMLM

ENSGT00550000074421_2_Linker_1_2 (727, 790)

Q----EIPQLNKVMCAAAEVAGQILIRLTHDFELNLDYEVYNSKMLLFVKELMQ
YATDIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAERTNRFIMKELNDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLQALLENLKLRKENKAVFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDSNMRG-NQTSITKPKRLNGYICYGIIAVII-FFLIG
FMIGYLGYCKRVEPQGDCAKQAGTQPSCP---EETEAFEPEEQLPGVP-RIFWADLKSAL
SDRLDAIDFTRAIKMLNENSYVPREAGSQKDSSLAFYIESQLRDYKLDKVWHDEHFVKIQ
VKGSS--QNSVSIVST-SGDGSQAYSVENPEGYVAYSK

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 422)

AATVTGKLVHANFGTKQDFEDL
N---MPVNGSLVIVRAGKITFAEKVANAESLNAIGVLIYMDHS-KFPIVN----ANLPVF
G

ENSGT00550000074421_2_Linker_0_1 (422, 545)

HAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAERLFQ--NMQG-DCPR
TWGTDSS-CKLVSS-----QDKNVKLSVNNVLKEIRIFNVFG-VIKG----------FEE
LDRY

PF04389 // ENSGT00550000074421_2_Domain_1 (545, 726)

IIVGAQRDAWGPGAA-KSSVGTSLLLTLARILSDMVLKGQFKPSRSIVFASWSGGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKAVVGSTNFKVSASPLLYSLIEKIM-KDVKHP
LTGL-SLYR--DS-NWISKVKKLSLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLDTPMD
TYETL

ENSGT00550000074421_2_Linker_1_2 (726, 789)

NG----EVPQLNRVARAAAEVAGQLVMKLTHGVELDLNYEMYNDEILRFVKEMNL
FRADIRDM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLNMQWLYSARGDFFRATSRLTTDYKNAEKTDRSVMREINDRIMKVEYHLLS
PYVSPREFP----FRHIFWGSGSHTLSALLEHLKLRKKLNGAFNQTLLENQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
------------------------------------MDRARSAVTNFIGRYPLSYTRFSL
TPQTDGDTSQVEMKLADDDEECGDQTLGEPVVK--QRSENNCKRICIKILLGAFLILSHT
KL--LTQFAGVIPLTLKRSSSSV----ILKFWYFFP-------FGRKRIGIIWVKIRA--
------KYFLHLLFVRKI-SKISREAGTSEEESVALMVHEEFGQMSLDKVWNDEHYVKLQ
ELGNS---PNKVTILS----NSNREETLQPSAYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SPAASVNGKLVYCHYGRKEDFQAI
QEKNIDLSENLVLVRSGLISFAEKVKNAELRGARGVLIYPEAS-DFTFPGSQTGSIDSPF
GHAHYGTGDPYTPGFPSFNHTQFPPSKSSGLPSIPVQTISSEDGKKLLE--KLEGADCPK
TWQVPFKLG------PQMKDTQNIKLEVTNVLVEKKIYNVFG-IIQG----------FEQ
SDHYVVVGAQRDSWGPGVA-KTAVGTSILLELAKLLSDMVKTDGFRPRRSIVFASWGAGD
FGSVGATEWLEGYLNNLHLKAFSYINLDSAIQGAGTFQVSASPLMNRVILQTL-KEVSDP
VSTDFTLYTQLGSQAWTKKIVPFSIEDSAYPFLAYSGIPSVSFSFQKENKPYAYLGTKMD
TLENFKQ-----LVDLDRMCRTAANFAAQIIMRLTHEQKLPLDYSSYSDVF

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LNVSIDLQR
QIKEIKELDLTVTWVNSARGDFSRAAASLTKEFAHSDLENALILRSLNDRIMKVEHGMLS
PYVSPKDTP----FRHIIYGAGNHTVAALMDHLSLRKTNKAAFDVDLFKNQLALLTWTLQ
GAANSLAGNIWDIDNNF--------

------------------------------------------------------------
-----------------------------------MMDQARSAISNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEESADNNMKA----GVRKPRRFNGRLCFGTVTVVI-FFLMG
FMIGYLGYCKRVEQK-DCVKLAETDTGYS---ENSE----IEQDIPKSARLYWADVKKLL
SEKLDAIEFTDTIRQLSQTPYIPREAGSQKDEDLAYYVENQFRDFKLSKVWRDEHYVKIQ
VKGSV--AQNSVTIIN--TNGG-VYLLENPEGYVAYSKAAE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEGL
N---YAVNGSLVIVRAGGITFAEKVANAQSFNAIGVLIYMDQT-KFPVVE----ADLSLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPAIPVQTISREAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFQ--NMEG-NCPT
SWNIDSS-CKLKLS-----QDKNVKLSVNNVLKETRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FEE
PDRYIVVGAQRDAWGPGAA-KSSVGTGLLLKLAQVFSDMVSRGGFKPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLIGKTM-QDVKHP
LDGR-SLYR--DT-NWISKVEKFSLDNAALPFLAYSGIPAVSFWFCEN-EDYPYLGTPLD
TYEK

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIT----KIPQLNKMVRAAAEVAGQFIIKLTHEVELNLDYDMYNNKILSFVKDLNQ
FRADIKAMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAEKTNRFFMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVENLKLRQRNISAFNETLFRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADNNMKA----SVRKPKRFNGRLCFAAIALVI-FFLIG
FMSGYLGYCKRVEQKEECVKLAETEETDK---SETM----ETEDVPTSSRLYWADLKTLL
SEKLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFHEFKFSKVWRDEHYVKIQ
VKSSI--DQNMVTIVQ--SNGN-LDPVESPEGYVAFSKPAD

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VSGKLVHANFGTKKDFEEL
S---YSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKN-KFPVVE----ADLALF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--KMEG-SCPA
RWNIDSS-CKLELS-----QNQNVKLTVKNVLKERRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 734)

NIFG-VIKG----------YEE
PDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIM-QDVKHP
VDGK-SLYR--DS-NWISKVEKLSFDNAAYPFLAYSGIPAVSFCFCED-ADYPYLGTRLD
TYEALTQ----KV

ENSGT00550000074421_2_Linker_1_2 (734, 791)

PQLNQMVRTAAEVAGQLIIKLTHDIELNLDYEVYNSKLLSFMKDLNQ
FKTDIRDMGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 906)

SLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVENLKLRQKNITAFNETLFRNQLALATWTIQ
GVANALSGDIWNIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFSGESLSYTRFSL
ARQADGDTSHVEMRAADGGDTDSXXXXXX-XX--------------X-X-XX--------
----X------XXXXXXXELP-AT---------ETVTETPGRGHPE-ALLLFWGDLKKIL
SQKLDTTEFTNTIKQLSEKPYIPREAGSANDESLAYFIENQFRAFKLGPVWHNEHYIKIQ
VKGSA---ENSLSTVT--ENGTSVILLDHSEGYVAYSKATTVTXXXXXXXXXXXXXXXXX
X---XXXXXXXXXXXXXXXXXXXXVANAESFNATGVLIYMDQA-DYPIVE----ADLAIF
GHAHLGTGDPYTPGFPSFNHTQFPPCQSSGLPNIPVQTISRSVAEKLFR--YMEQ-DCPA
TWKTGSL-CKMQSL-----EGKNIKLTVNNVLKEVKVLNVFG-VIKG----------FEE
PGHYVIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVKHP
VTGL-SLYR--DS-NWASKTAELSFDNAAFPFLTYSGIPSVSFWFCEE-KDYPYLNTPKD
TYEVLID----RVPQLNKLARTAAEVAGQLVIRLTLDLETDYE

PF04253 // ENSGT00550000074421_2_Domain_2 (764, 909)

YSR----VLSFKD--II
YRTDIKGMNLNLQWLYSARGDFFRAVSRLTTDLNNADKTNKFVMRELNERIMKVEYHFLS
PYVSPKDSP----FRHIFWGAGSHTLPALLKNLELRQKNSAAFNETQLRNQLALATWTIQ
GAANAIAGDIWDIDNEF--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MIGYLGYCKGVEPKTECERLAGTESP-----AR---EEPEEDFPAAP-RLYWDDLKKKL
SEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDRT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CKMVTS-----GNKSVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----RIPELNKVARAAAEVAGQFVIKLTQDIELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------AMDHARAAISNLFGGEPTSYTRFSI
ARQTDGDNSHVEMNLAADEEEGGEIGKPEHLHASMPPPRRNGKNLCLIIMAAVV-LLLIG
FLIGYLSYRGRMQRVNRCLDGSGNCEMTPTASYFSD-DGMEEEEVPGPRILYWPELRNML
STKLSAPCLEANMRQR-E-GKNSFEAGKAEDESTASYIHDQFTLFRLDDVWNDEHYVRLQ
DRGSS---KNQVWSIE----NGREDLVESPDEYVAYSKNG

PF02225 // ENSGT00550000074421_2_Domain_0 (341, 424)

TVIGRPVYVNYGRKEDFQQI
RIMGIPMNGTIIIFRAGKITLAEKVANARKEGAAGALMFPDFS-KNNKA-----DAYVPF
GHA

ENSGT00550000074421_2_Linker_0_1 (424, 544)

HLGTGDPFTPGFPSFNHTQFPPVESSGLPRIPVQTISRQAATKLFG--KMDGDKCVP
DWTG-IMGCKMTG-----NRNMTVKLTVNNVMVDRKILNIFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 727)

YVVLGAQRDSWGPGAA-RAGVGTAILLELARVISDMVKSDDYKPRRSIIFASWSAGE
YGAVGATEWLEGYTTTLHAKAFTYINLDTAVLGSRDVKISASPLLYSLLETVM-KRVKDP
TKDSGNLYNRVGS-DWIKRVVPLDLDNAAFPFLAYSGIPVVSFGFYDEGDEYSFLGTTED
TLANLK

ENSGT00550000074421_2_Linker_1_2 (727, 789)

E----KTDKLYDLMRAAAEVAGQIALRLTHDHQLFLDFDRYSEELLSFQEKLWH
FEPNVKEL

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLTLNWLYFARGDFQRAADALRRDIANSDRENRIVRRALNDRMMKVEYDFLS
PYLSPKDAP----FRHIFFGKGSHTLQSLLENLMQLKVNVSSVDVDELKEQLALVTWTIK
GAANALVGDIWNTDNEI--------

------------------------------------------------------------
---------------MLAAGCWLLTACGSSVWQLKMMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDSNMRG-NQTSITKPKRLNGYICYGIIAVII-FFLIG
FMIGYLGYCKRVEPQGDCGKEAGTQPSCP---EETEAFEPEEQLPGVP-RIFWADLKSTL
SDRLDAVDFTRAIKMLNENSYVPREAGSQKDSSLAFYIESQLRDYKLDKVWHDEHFVKIQ
VKGSS--QNSVSIVST-SGDGSQAYSVENPEGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKQDFEDL
N---MPVNGSLVIVRAGKITFAEKVANAERLNAIGVLIYMDHS-KFPIVN----ANLPVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAER

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFQ--NMQG-DCPS
TWGTDSS-CKLVSS-----QDKNVKLSVNNVLKEIRIF

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 743)

NVFG-VIKG----------FEE
LDRYIIVGAQRDAWGPGAA-KSSVGTSLLLTLARILSDMVLKGQFKPSRSIVFASWSGGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKAVVGTTNFKVSASPLLYSLIEKIM-KDVKHP
LTGL-SLYR--DS-NWISKVKKLSLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLDTPMD
TYETLNG----QVPQLNRVARA

ENSGT00550000074421_2_Linker_1_2 (743, 790)

AAEVAGQLVMKLTHGVELDLNYEMYNDEILRFVKEMNL
FRADIRDMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LNMQWLYSARGDFFRATSRLTTDYKNAEKTDRSVMREINDRIMKVEYHLLS
PYVSPREFP----FRHIFWGSGSHTLSALLEHLKLRKKLNGAFNQTLLENQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARATISNLFGGEPLSYTRFSL
ARHIDGDNSHVEMKLAADEEENADSNVRA----NVKTPRRCTGSLCYSAIAVAL-FFLIG
FMIGYLGYCKRIEAKGACERPAVTEVTKG---SEDLEQEE-EEMPQLPSRLYWEDLKAML
SKKLDPAKFGSTIKQLNENTYIPRVAGSAQDENLAYFVENQFSEYKLSKVWRNEHYVKIQ
VQNST--APNSVTLT--GANNDLLYLVENPEGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 426)

VTGKLVHANFGTKEDFENL
N---TSVNGSLVIVRAGKIPFAEKVSNAESLNALGVLIYLDQA-KFPIVR----ADTPIF
GHAHL

ENSGT00550000074421_2_Linker_0_1 (426, 519)

GTGDPYTPGFPSFNHTQFPPSQSSGLPAIPVQTISRQGAEKLFE--NMEG-ECPT
SWRTDSS-CKLHSN-----QNRNVKLTVNNELKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 707)

NIFG-VIKG----------VEE
PDRYVVVGAQRDSWGPGAA-KASVGTALLLELARTFSDMVLNGGFKPCRSIIFVSWSAGD
FGAVGATEWLEGYLTSLHLKVVTYINLDKAVLGTTNFKVTGSPMLYKLIEKTM-QEVKHP
LTGM-SLYK--DS-NWVSKVEKLSLDNAAFPFLAHSGIPAVSFCFCED-TDYPFLSTAMD
SYDVLMR----EIPQLNKLMYAAAEVAGQFLIKLTHDFELNLDYEIYSNKMLSFLRELMQ
YRADIKEMGLSLQWLYSARGDFFRAASRLMTDFHNAERTNRFIMKELNDRIMKVEYYLLS
PYVSPRESP----FRHIFWGSGSHTLQALLENLKLPPLSCVAVQSVIFTVFCTGPVFSVA
K------------------------

------------------------------------------------------------
------------------------------------MDNARSAISNLFGSGPLSYTRFSL
TRQMDGDS-HVEMKLSE-EEDGGENGMTDHVHAHVAKPRSSRRNLWCKTAATGL-LFLIG
FLIGYLSYHGRIQATSTCAGERIACANAAT----TPSLEDEYVEPEVERVPYWNDLRTML
FNRLRAVNMNKDT----R-QLLSYEAGSERDDSLANDIHVQLTNAKLDKVWNDEHYVKLQ
VPSSL---PNKVVA----QSSGGSEKLETGDGYVAYSA

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 416)

TGRATGKPVYANYGRAEDFQKL
KDLKIPVNGSVVLVRTGKITFAEKVANAEGLNAVGVLIYCEPA-GSQ--S----T

ENSGT00550000074421_2_Linker_0_1 (416, 544)

KEGLF
GHAHLGTGDPFTPGFPSFNHTQFPPAKSSGLPQIPVQTITSAAVESLFS--KMN-EDPPE
EWKSRVF-INKMT--S---DETTVTLEVNNQMVERRIYNIFG-VIQG----------FDE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 724)

YVVIGAQRDSWGPGAA-KAGVGTTMLLELARAISSMVKTGGYKPKRSIVFASWSAGE
FGAVGATEWLEGYSATLHSKAFAYINLDAAVLGSSKFKVSASPMLYKVVEQTM-MEVKPP
VKKNRPPTR--GS-DWTKEVVPLSMDNAAFPFLAYAGIPAISFSFYDDDEGYPYLGTKMD
SWE

ENSGT00550000074421_2_Linker_1_2 (724, 789)

NLGS----AVTNLEDVLQTATEVAGQMAIRMTYSHELYLDYEQYNQELINFIMKISQ
YKQDIKAM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

NLTLQWLYSARGDFSRATAALREDFRNTDLNNKLICRQMNDRVMKVEYNFLS
PYASPKDTP----LRHIIFGSSSYTLSALLDHLSLRRSNPSAFNADLLKNQLALATWTIQ
GAANALSGDIWNIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSRVEMKLAMEEEENADHSVKA----NVTKPKRRTGTLCCAAIALII-FFLVX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX------XXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXKLNENSYIPREAGSQNDENLAYFIENQFHDFKLNKVWRDEHFVKIQ
VKDSA---QNSVTIQN--KNNEAPFLVENPVGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKATTVTGKLIHANFGTKEDFENL
K---SPVNGSLVIVRAGKITFAEKVANAERLNAIGVLIYMDQA-RFPIVK----ADLPLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISREAAEKLFG--NMEG-NCPS
EWQIDSS-CKLVI------PGKNVKLSVNNALKEIRILNIFG-VIKG----------FEE
PDRYIVVGAQRDSWGPGAA-KASVGTALLLELARIFSDMVLKGGFKPSRSIIFASWSAGD
FEAVAEC----GYLASLHLKAFAYINLDKAVLGTINFKVSASPLLYTLIEKTM-QDVKHP
VTGQ-YLYQ--DS-NWINKVEKFSLDNAAYPFLAYSGIPSVSFWFCEXXXXXXXXXXXXX
XXXXXXX----XXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

XXXXXRLNQ
YRADVKELGLSFQWLYSARGDFFRATTRLTTDFKNAEKTNRFTIREINDRIMKVEYHFLS
PYVSPRDSP----FRHIFYGSGSHTLSALLENLSLRHQNNGAFNETLLRNQLGLATWTIQ
GAANALSGDIWDIDNE---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------FPC--SSFLLSNKKKKL
SSVMLEKSISSSVKTLSE-KYSSHEAGSKEDEMFGYFIYQQFRDLKMDKVWKDKHYVKLQ
FKSRY---VDNQVVAL--KQW-FSTYLMEMNGYVAYSVNSTANVS----KTGLMCSFEQL
KSQ

PF02225 // ENSGT00550000074421_2_Domain_0 (364, 400)

QVTIDGSMVLVRAGKLSFAEKVENAEAYNAVGVLIY

ENSGT00550000074421_2_Linker_0_1 (400, 544)

LARG-DFDIID----ADIVPF
GHAHLGTGDPFTPGFPSFNHTQFPPSQSSGLPTIPVQTISRSQALKLFR---MNGADCPQ
GWDGDSK-CKISSEVN-------VRLTVNNVLEERKLLNIFG-VVKG----------IDE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 707)

YVVIGAQRDAWGPGAA-KSLVGTSLLLEVARAYSDLV-KGGYKPRRSVVFASWSGGE
FGAVGATEWLEGYLSTLHQKAITYINLDTAVLGSSNFKVSASPLLYTLIEKTM-KEVNHP
VTGT-ALFR--DT-NWISEVEPLTLDNAAYPFLAYSGIPSVSFCFC

ENSGT00550000074421_2_Linker_1_2 (707, 789)

E-NKAYKYLGTSLD
SYNELIK----SIPQLKKLMYGAAEVTSQMVIRLTRDHELYLDYERYNEELFSFVKKLVP
YMSNLKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

NLSLQWLFSARGDFSRATRDLTNDLFRTDTANRLVNREINDRIMKVEYSLLS
PYVSPKESP----FRHIFWGSGSHTLSALLDHIKHFNKRDGNFNETLFRNQLALATWTIQ
GAANALAGNIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLVRYFQLYFCIC--
-----------------------------------------KN--VKYTIQLWN-FVSLG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPGEDFRAAP-RLYWDDLKKKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSRVWRDQYFVKIQ
VKDS---AQNSVIIVD--KNGRLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 402)

VTGKLVHANFGTKKDFEDL
D---TPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVN----SELSFF
GHVIVGTTGMLNLGQGTITQN------------L--------RLLSDSR--NMEG-DCPS
DWKTDST-CRMVTS-----ESKNVKLTVSNVLKEIKILNIFG-VIKG----------FVE
PGKDPPP----------------APPLLFFVFFAVLKDVAR------------------E
GGRVG----------------------IDGVSPCYNFKVSASPLLYTLIEKTM-QNVKHP
VTGQ-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKELIE----RIPELNKVARAAAEVAGQLVIKLTHDVELNLDYERYNSQLLSFVRDLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FCHVFWSSGSHTLSALLENLKLCKQNNGAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENVDNNMRG-NHTNVTKPKRLNGYICYGTIAVIV-FFLIG
FMIGYLGYCKRVEPKADCERPAGREPSCT---EETETFETEEQLPETR-RIFWADLKSTL
SKRLDAIDFTSAIKMLNGNSYVPREAGSQKDESLAFYIENQFRELKLSKAWHDEHFVKIQ
VKGSA--HNSVTIVSE-SGSSSTVYLVENPEGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKATTVTGKLVHANFGTKKDFEDL
N---MPVNGSLVIVRAGKITFAEKAANAESLNAIGVLIYMDQT-KFPIVN----ADLPVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAEKLFR--NMEG-DCPP
IWGLDSS-CKLVSS-----QNKNVKLTVNNVLKEIRIFNIFG-VIKG----------FEE
PDRYVIVGAQRDAWGPGAA-KSSVGTSLLLKLAQILSDMVLKGQFKPSRSIVFASWSGGD
FGAIGATEWLEGYLASLHLKAFTYINLDKAVLGTSKFKVSSSPLLYSLIEKTM-QDVKHP
VTGL-SLYR--DS-NWINKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTPMD
TYEVLNQ----NVPQLNKMARAAAEVAGLLVIKLTHDVELNLNYEMYNDKI

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LWFVREMNQ
FRADIKEMGLNLQWLYSARGDFFRATSRLTTDYKNAERTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALLEHLKLRQKNNGAFNETLLKNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARATFSNLFGGEPLSYTRFSL
ARHVDGDNSHVEMKLAADEEENAD-NMRA----NVKAPRRCIRSICYVVIAITI-FFLIG
FMIGYLGYCRRVEPKAECERPAVMDVMKE---SEDLEV--EEVMPEASSHLYWEDLKTML
SEKLSNAKFSDTVKQLNENAYVPREAGSEKDENLAYFVENQFSEYKLSKVWRNEHYVKIQ
VKNST--APNSVTVVS--ANNGMVYLVENPEGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
N---TSVNGSLVIVRAGKITFAEKVSNAAGLNALGVLIYLDNT-QFPITK----ADLPFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPTIPVQTISRQAAEN

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFA--NMER-DCPT
SWRTDVS-CRMQSR-----QDRNVKLIVNNVLKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 727)

NIFG-VIKG----------VEE
PDRYVVVGAQRDSWGPGAA-KASVGTALLLELARTFSDMVLKDGFKPHRSIIFVSWSAGD
FGAVGATEWLEGYITSLHLKAVTYINLDKAVLGTTNFKVTGSPMLYKLIEKTM-QEVKHP
LTGA-SLYK--DS-NWVNKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-KGYPYLSTTLD
NYDMLM

ENSGT00550000074421_2_Linker_1_2 (727, 790)

R----EIPQLNKLMYAAAEVAGQFLIRLTHDLELNLDYEVYNSKMLLFLRELMQ
HTTDIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHSAERTNRFIMKELNDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLQALLDNLKLRKENKAAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADNNMKA----SVRKPKRFNGRLCFAAIALVI-FFLIG
FLSGYLGYCKRVEQKEECVKLAETEETDK---SENM----ETEDVPKSSHLYWADLKTLL
SEKLNSIEFTDTIKQLSQNTYTPREAGSQKDENLAYYIENQFHEFKFSKVWRDEHFVKIQ
VKSSV--VQNMVTIVR--SDGS-LESVESPEGYVAFSKAAE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VSGKLVHANFGTKKDFEEL
T---YSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKN-KFPVVE----ADLALF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--KMEG-SCPA
NWNIDSS-CKLQLS-----QNQNVKLTVNNILKERRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 726)

NIFG-VIKG----------YEE
PDRYVIVGAQRDAWGTGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIM-QDVKHP
IDGK-SLYR--DS-NWINKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-ADYPYLGTRLD
TYEAL

ENSGT00550000074421_2_Linker_1_2 (726, 791)

IQ----KVPQLNQMVRTAAEVAGQFIIKLTHDIELNLDYEMYNSKLLSFMRDLNQ
FKAAIRDMGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 906)

SLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVENLELRQKNITAFNETLFRNQLALATWTIQ
GVANALSGDVWNIDNEF--------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------G
FLTGYLSYRGRMQAEKPCAANPDVTS------YSA--QTDDLAEPVKPVELYWGDLKQKL
EERLKSASFQTNIRK--V-FSTSHEAGSPGDEVLAGEIHSLFEAYRLDKVWNDEHYVRLQ
APGKS---PNVVSL------EGPNEPVETPKAYVAYSE

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 406)

SAEVSGKPVYANYGRDEDFRKL
LENVPNINGTVVLVRAGEIPFAEKAANAKKLGAAGVLIYPDPA-D

ENSGT00550000074421_2_Linker_0_1 (406, 544)

FRNLR----QDASLF
GHAHLGTGDPYTPGFPSFNHTQFPPVESSGLPRIPVQTISSSAARKIFS--VMNGPVCPA
PWTGTTGATYK---FGSTASGRNVKLQVKNELVEKKILNIFG-VIKG----------FVE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 725)

YVVLGAQRDSWGSGAV-KAGVGTALLLELARAFSDMVKKDGYKPRRSVVFASWSAGD
FGAVGATEWLEGYAASLHLKAFAYINLDSAVTGSRDFKFSASPMLKRLLEEAV-TGTEKA
P--PLGLYSGEGP-GWLIFGKPLRLDDASFPFIAYSGIPAISFSFYDGESVYPFLGTEDD
TIDN

ENSGT00550000074421_2_Linker_1_2 (725, 791)

LLSFFGSSSGQLDKMMLAAAEIAGRMALRMTHDHELYLDFTSYNDRLLRLVGKFLA
YRKDLEKIGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 840)

GVQWLMSARGDFNRATQALTLDVANTDLTNTVACRALNDRIMKVGCHFSS
LGCPQKSEKLIVSLLNVMWNVSLQ----------------GSFAKS--------------
-------------------------

------------------------------------------------------------
------------------------------------MDHARAALSSLFSAEPMSYTRFSI
ARQTDGDNSHVEMKLSADDEEGVDIERPEHVHDSMAQPQRNGKKLCFLVIAAVL-LLLIG
FLIGYLSYRGRMQLAARCQDGSGRCEITPTASYLVDGDETVEEEIQGPPVIYWPQLKAML
SDKLLAKNLGDRLRQR-A-GLDSFEAGEAEDTNMATYIHEQFNSFFLDKVWNDEHYIKLQ
IRGST---KNKVSVLI----NDSEEILEMPDAYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SESGSFSGKPVYVNYGLKKDIETI
QKSVTPLNGTIVIVRAGKITLAEKVANAKEAGAVGVLMYMDSF-KYGIT-----GTLTPF
GHAHLGTGDPYTPGFPSFNHTQFPPVESSGLPHIAVQTISSSAAAKLFS--KMDGDSCSE
DWKGGIHSCKVTTKQ---ESKIMVKLDVNNSMKDRKILNIFG-AIQG----------SEE
PDRYVVIGAQRDSWGPGVA-KAGTGTAILLELARVISDIVKNEGYKPRRSIIFASWSAGD
YGAVGATEWLEGYSAMLHAKAFAYINLDAAVLGANHVKISASPLLYMLLERIM-KGVKDP
AQGSRTLLDRVGS-DWVKAVVPLGLDNAAFPFLAYSGIPVVSFGFYNKDEEYHFLNTKDD
TLENLRK-----IDNLDALLRAAAEVAGQVALRLTHDHELFLDFGRYGEELLAY

PF04253 // ENSGT00550000074421_2_Domain_2 (775, 847)

QEKFLP
YVKDVQELGLTLDWLF-ARGDFQRAADALRRDIANSDRENKVIRRALNDRIMKVEYDFLS
PYLSPKEVP---------------------------------------------------
-------------------------

------------------------------------------------------------
-----------------------------------MMDQARSALSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENVDNNVRG-NHACVTKPKRFNRSTFWGTTAVII-FFFIG
FMVGYLGYCKRVEPKGECRE---TEPPKI---EGTESSEIEEYFPEVPSRLFWTDLKAML
SEKLNAADFSNTIRRLNENTFVPREAGSQKDESLAFYLEDQFRKRQLSKVWHDEHFVKIQ
VKGST--RNSV-TIVR--TNGEMVYLVENPVGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKATTVTGKLIHANFGTKKDFEDL
T---SPVNGSLVIVRAGKITFAEKVKNAESLNAIGVLIYMDRT-KFPIVD----AEVPVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRACAEQLFQ--NMEE-DCPS
TWKTDSS-CRLVTS-----QNNNVKLTVTNELKEIRILNVFG-VIKG----------FEE
PXXXXXXXXXXXXXXXXXX-XXXXXXXXXLELAQIFSDMVLKDGFKPSRSIVFASWSAGD
FGAVGATEWLEGYLSSLHSKAFTYINLDNAILGTSNFKVSASPLLYSLLEKVM-QNVKHP
VTGQ-SLYQ--DS-NWISKVEKLSFDNAAFPFLAYSGIPAVSFRFCED-TDYPYLGTSMD
TYQVLYR----EIPQLDKMARAAAEVAGQLIIKLTHEAELNLNYEMYNDEI

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

FSFVRDMNQ
FRADIKEMGLSLQWLYSARGDFFRATSKLTTDYKNAERTDRFVMRGINDRIMKVEYHFLS
PYVSPRDSP----FRHIFWGSGSHTLSALLEHLKLRQKNNSAFNQTLFKNQLALATWTIQ
GAANALAGDIWNIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----NVTKPKRCSGSICYGTIAVIV-FFLIG
FMIGYLGYCKGVEPKTQCERLAGTESP-----VR---EEPGEDFPAAR-RLYWDDLKRKL
SEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGSLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
H---TPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVN----AELSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTVSRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CRMVTS-----ESKNVKLTVSNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSGVGTALLLKLAQMFSVMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QNVKHP
VTGQ-FLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----RIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSFVRDLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FRHVFWGSGSHTLPALLENLKLRKQNNGAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADSNMKA----SVRKPKRFNGRLCFATIAVVI-FFLIG
FMIGYLGYCKRVEQKEECVRLAEAEEADK---SEND----ETEYVPKSSRLFWADLKTLL
SEKLNSIEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQ
VKNSV--SQNLVTIN---SGSN-IDPVEAPEGYVAFSKAGE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEEL
N---YSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRN-TFPVVE----ADLQFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFK--NMEG-NCPP
SWNIDSS-CKLELS-----QNQNVKLTVNNVLKETRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------YEE
PDRYIVVGAQRDAWGPGVA-KSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGD
YGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIM-QDVKHP
IDGK-YLYR--DS-NWISKIEELSLDNAAFPFLAYSGIPAVSFCFCED-EDYPYLGTKLD
TYEI

ENSGT00550000074421_2_Linker_1_2 (725, 791)

LIQ----KVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQ
FKADIKDMGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 906)

SLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQ
GVANALSGDIWNIDNEF--------

------------------------------------------------------------
-----------------------------------------LVAQARFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----NVTKPKRCSGNICYGAIAVIV-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPGEDFRAAP-RLYWDDLKKKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSRVWRDQHFVKIQ
VINSIFSAQNLVIIVDKNKNGRLVYLVENPGSYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---TPVNGSLVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVN----AELSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CRMVTS-----ESKSVKLTVSNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 631)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKA

ENSGT00550000074421_2_Linker_1_2 (631, 790)

VLGMFHVCS-----LFSLIKAHTSQREKHT
AL-R-N--------------------LARSLFRAYDT---IEQGFCRT-WKK-LVTLGNG
RLLLLEF----TIPELNKVARAAAEVAGQLVIKLTHDVELNLDSERYNSQLLCFVRDLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FRHVFWGSGSHTLSALLENLKLRKQNNGAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENTDNNTKA----NGTKPKRCGGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----AR---EEPEEDFPAAP-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----RIPELNKVARAAAEVAGQFVIKLTHDTELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKRDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDSNMRG-NQTSIAKPKRLNGYVCYGIIAVIV-FFLIG
FMIGYVP-------------------------RGDRTFESEEQLPGVP-RIFWADLKSTL
SGKLDAVDFARAIKMLNENSYVPREAGSEKDTSLAFFIENQLQDCKLGKVWHDEHFIKIQ
VKGSS--QNSVSIVST-SGNGSQAYPVESPEGYVAYSK

PF02225 // ENSGT00550000074421_2_Domain_0 (339, 422)

AATVTGKLVHANFGTKQDFEDL
N---MPVNGSLVIVRAGKISFAEKVANAESLNAIGVLIYMDYS-KYPIVN----ANLPVF
G

ENSGT00550000074421_2_Linker_0_1 (422, 544)

HAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTITRAGAEKLFQ--NMEG-DCPR
IWGTDSS-CKLVSS-----QDKNVKLSVNNVLKEIRILNVFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 727)

YVIVGAQRDAWGPGAA-KSSVGTSLLLTLARILSDMVLKGQFKPSRSIVFASWSGGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKAVVGTTNFKVSASPLLYSLIEKIM-KDVKHP
LNGL-SLYR--DS-NWISKVQKLSLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTPMD
TYETLN

ENSGT00550000074421_2_Linker_1_2 (727, 789)

R----EVPQLNRVARAAAEVAGQLVIKLTHGVELNLNYEMYNDEILRFVKEMNL
FRADIRDM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLNMQWLYSARGDFFRATSRLTTDYKNAEKTDRSVMREINDRIMKVEYHLLS
PYVSPREFP----FRHIFWGSGSHTLSALLEHLKLRKKNNGAFNQTLLENQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENTDNNTKA----NGTKPKRCGGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----AR---EEPEEDFPAAP-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 542)

LFG--NMEG-DCPS
DWKTDST-CKV-----------SVKLTVSNCLKETKILNIFG-VIKASLEAYLNSSSFVF
K

PF04389 // ENSGT00550000074421_2_Domain_1 (542, 725)

DHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----RIPELNKVARAAAEVAGQFVIKLTHDTELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADNNTKA----GVAKPKRCNGSI-YGTIAVII-FFTIG
FMIGYLGYCKHVEPKTECQRLAGTESP-----AV---ENPEENFPVAP-QLYWDDLKKKL
SEKLDTTDFTSTIKLLNENLYVPREAGSQKDENLAWYIENQFRECKLSKVWRDEHFVKIQ
VKDS---AQNSVTITG--TNSEFVYLVENPGGYVAYSQNAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTEKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESSNAIGVLIYMDKT-KFPIVN----ADVSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAER

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFE--NMEG-DCPS
DWKTDSS-CRMVTS-----QNKSVKLSVSNVMKQIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDRYVVVGAQRDSWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFRPSRSIVFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYSLIEKTM-QEVKHP
VTGL-SLYQ--DS-NWASKVEKLTFDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----KIPQLNKVARAAAEVAGQLMIKLTHDVELNLDYERYNSQLLLFLRNLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFKNSEKTDRFVMKELNDRIMKVEYYFLS
PYVSPRESP----FRHIFWGSGSHTLSALLENLKLRKTNNRAFNETLFRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------KLINTVRSLSE-KYSSHEAGSKEDEMIGYFIYQQFRDLKMDKVWKDKHYVKLQ
FKSSG---AQNVVTML--NE---SNDPMEMNGYVAYSVNSTANGMLIYVSYGSKNDFEQL
KWQQVTIDASMVLVRAGKLSFAEKVENIEAYNVAGVLIYLARD-DFDIID----ADIVPF
GHVHLGTGDPFTPGFPSFNHTQFPPSQSSGLPTIPVQTISRSQALKLFS---K-----MN
GWDGGNK-CKISSEVN-------VRLIV-NVLEERKLLNIFG-VVKG----------IDE
PDH

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 707)

YVVIGAQRDAWGPGAA-KSLVGASLLLEVAHAYSDLV-KGGYKPRRSVVFASWSGGE
FGAVGATEWLESYLSTLHQKAITYINLDTAVLGSSNFKVSASPLLYTLIEKTM-KEMNHP
VTGT-ALFR--DT-NWISEVEPLTLDNAAYPFLAYSGIPSVSFCFC

ENSGT00550000074421_2_Linker_1_2 (707, 789)

E-NKAYKYLGTGLD
SYNELIK----SIPQLKKTD-------------PNGDHELYLDYERYNEELFSLVKKLVP
YMSNLKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

NLSLQWLFSARGDFSRATRDLTNDLFHTDTANRLVNREINDRIMKVEYSLLS
PYVSPKESP----FRHIFWGSGSHTLLALLDHIKLFNKKDGNFNEKLFRNQLALATWTIQ
GATNALAGNIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDHARSAISNLFSGEPLSYSRFSL
TRQMGGDTSHVEMKLAADEEDSGESSSIENNHPHVTKRKTIGGNICFGIIAITI-FFLIG
FMVGYLGYCKQLETNVKCSDNSNREIGTTTEVETGSPEEPPFLEPQ--PELSWNDLKKML
SRRLDAKNFTDTVSILSK-NYASHEAGSKEDEMFGYFIYQQWKGLKMDKVWKDKHFVKLQ
VKGSG---PQNSVTIL--DESGNSSEVMPTDGYVAYS

PF02225 // ENSGT00550000074421_2_Domain_0 (338, 402)

DNSTANGTLVYANYGTKEDFEQL
KSK-TAVDGSVVLLRAGKLSFAEKVANADAYNAVGVLIYLA

ENSGT00550000074421_2_Linker_0_1 (402, 546)

RS-DFDIVD----AEVVPF
GHAHLGTGDPFTPGFPSFNHTQFPPSQSSGLPNIPVQTISRSQASKLFN--VMDGEDCPT
SWRGDDK-CKMNSKTN-------VRLTVNNVLEEKKLLNIFG-VVKG----------IDE
PDRFV

PF04389 // ENSGT00550000074421_2_Domain_1 (546, 732)

VVGAQRDAWGPGAA-KSLVGTSLLLGIAKAYSDLVSKDGYKPRRSVVFASWSGGE
FGAVGATEWLEGYLSTLHLKAYTYINLDTAVVGSNNFKVSASPLLYTLIERIM-KEVNHP
VRGG-TLFR--DT-NWISEVEPLSLDNAAYPFLTYSGIPSVSFRFCE-TKPYRYLGTKLD
TYDNLSK----

ENSGT00550000074421_2_Linker_1_2 (732, 789)

DIPSLRELMYAAAELTVQMVIRLTRDHELYLDYERYNEELFKFVRKLLP
FKSELKSL

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

NLNFQWLFSARGDFSRATHDLTNDLYRTDTTNILVNREINDRIMKVEYSLLS
PYVSPKETP----FRHIFWGSGSHTLSALLSHLQLLKKKDINFNETLFRNQLALSTWTIQ
GAANALAGNIWDINEF---------

------------------------------------------------------------
--------------------------MTKLCNVLMLFVLLSFSKKYQFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENTDNNMKA----SVRKHRRLNGRLCFGTIAVVI-FFLIG
FMIGYLGYCKRTEQK-DCVRLAETETGNS---EIIQ-----EENIPQSSRLYWADLKKLL
SEKLDAIEFTDTIKQLSQT---SREAGSQKDENLAYYIENQFRDFKLSKVWRDEHYVKIQ
VKGSA--AQNAVTIIN--VNGD-SDLVENPGGYVAYSKATT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VSGKLIHANFGTKKDFEDL
K---YPVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDQT-KFPVVE----AELSLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRKAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFQ--NMET-NCPP
SWNTDSL-CKLESS-----QGINVNLSVNNVLKETRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 732)

NIFG-VIKG----------FEE
PDRYIVVGAQRDAWGPGAA-KSSVGTGLLLKLAQAFSDMVSRGGFKPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTRNFKVSASPLLYTLIEKTM-QDVRHP
IDGK-PLYR--DS-NWISKVEDLSLDNAAFPFLAYSGIPAVSFWFCEN-EDYPYLDTNLD
TYEKLIQ----

ENSGT00550000074421_2_Linker_1_2 (732, 790)

KVPQLNKMVRAAAEVAGQFIIKLTHDIELNLDYDMYNNKILSFVKELNQ
FRADIKAMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHNAEKTNRFVVREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLTALVENLKLRQKNSSAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENADNNTKA----NGTKPKRCNGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPEEGFPAAS-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYIENQLREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNATGVLIYMDRT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPA
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVIVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----KIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLENLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENADNNMKA----SVRKPKRFNGRLCFAAIALVI-FFLIG
FMSGYLGYCKRVEQKEECVKLAETEETDK---SETM----ETEDVPTSSRLYWADLKTLL
SEKLNSIEFADTIKQLSQNTYTPREAGSQKDESLAYYIENQFHEFKFSKVWRDEHYVKIQ
VKSSI--GQNMVTIVQ--SNGN-LDPVESPEGYVAFSKPTE

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VSGKLVHANFGTKKDFEEL
S---YSVNGSLVIVRAGEITFAEKVANAQSFNAIGVLIYMDKN-KFPVVE----ADLALF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--KMEG-SCPA
RWNIDSS-CKLELS-----QNQNVKLIVKNVLKERRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 734)

NIFG-VIKG----------YEE
PDRYVVVGAQRDALGAGVAAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIM-QDVKHP
VDGK-SLYR--DS-NWISKVEKLSFDNAAYPFLAYSGIPAVSFCFCED-ADYPYLGTRLD
TYEALTQ----KV

ENSGT00550000074421_2_Linker_1_2 (734, 791)

PQLNQMVRTAAEVAGQLIIKLTHDVELNLDYEMYNSKLLSFMKDLNQ
FKTDIRDMGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 906)

SLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALVENLKLRQKNITAFNETLFRNQLALATWTIQ
GVANALSGDIWNIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARATFSNLFGGEPLSYTRFSL
ARHVDGDNSHVEMKLAADEEENAD-NMRA----NVKAPRRCIRSICYVVIAITI-FFLIG
FMIGYLGYCRRVEPKAECERPAVMDVMKE---SEDLEV--EEVMPEASSHLYWEDLKTML
SEKLSNAKFSDTVKQLNENAYVPREAGSEKDENLAYFVENQFSEYKLSKVWRNEHYVKIQ
VKNST--APNSVTVVS--ANNGMVYLVENPEGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
N---TSVNGSLVIVRAGKITFAEKVSNAAGLNALGVLIYLDNT-QFPITK----ADLPFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPTIPVQTISRQAAEN

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFA--NMER-DCPT
SWRTDVS-CRMQSR-----QDRNVKLIVNNVLKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 727)

NIFG-VIKG----------VEE
PDRYVVVGAQRDSWGPGAA-KASVGTALLLELARTFSDMVLKDGFKPHRSIIFVSWSAGD
FGAVGATEWLEGYITSLHLKAVTYINLDKAVLGTTNFKVTGSPMLYKLIEKTM-QEVKHP
LTGA-SLYK--DS-NWVNKVEKLSFDNAAFPFLAYSGIPAVSFCFCED-KGYPYLSTTLD
NYDMLM

ENSGT00550000074421_2_Linker_1_2 (727, 790)

R----EIPQLNKLMYAAAEVAGQFLIRLTHDLELNLDYEVYNSKMLLFLRELMQ
HTTDIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFHSAERTNRFIMKELNDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLQALLDNLKLRKENKAAFNETLFRNQLALATWTIQ
GVANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADNNTKA----NVTKPKRCSGSICYGTIAVIV-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPGEDFPAAR-RLYWDDLKRKL
SEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGRLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
Y---TPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQT-KFPIVN----AELSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CRMVTS-----ESKNVKLTVSNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSGVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QNVKHP
VTGQ-FLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LIE----RIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSFVRDLNQ
YRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLS
PYVSPKESP----FRHVFWGSGSHTLPALLENLKLRKQNNGAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSTLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENGDSNMGG-NHANVTKPRRFGGTICYGIIAIII-FFLIG
FMIGYLGYCKRAEAKTKCEKPAVTESSDT---EETENSEAEEYFPETP-HLFWGDLKTML
SQKLDPAAFTSTIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX---XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X---XXXXXXXXXXXXXXXXXXXXVANAESFNAAGVLIYMDHA-MFPIVK----ADLPLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAEKLFG--HMEG-DCPS
IWKTDSS-CKLLSL-----ENKNVKLTVKNVLKETKIFNIFG-VIKG----------FEE
PDRYVVVGAQRDAWGSGAA-KSSVGTALLLELARIFSDMVLKGGFKPKRSIVFASWSAGE
FGAVGATEWLEGYLSTLHLKAFTYINLDKAVLGTGNLKVSASPLLYSLIEKTM-QDVKHP
ITGQ-TVYW--DS-NWINNVEKLSIDNAAFPFLAYSGIPAVSFHFGED-TDYPYLGTTMD
TYEVLSQ----KIPQLNKMACAAAEVAGQLIIKLIHDIELNLDYEKYNDKL

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFLKDIKE
FKANIKEMNLTLQWLYSARGDFFRAVSKLTTDFRNAEKADKFVMREINNRIMKVEYHFLS
PYVSPRDSP----FRHIFWGSGSHTLSALLENLKLHQKNSNAFDETLLRNQLALITWTIQ
DAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLVRYFQLYFCV---
----------------------------------------CKNV-KYT--NSIP-VIEFR
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPEEGFPAAP-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDRT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFG--NMEG-DCPA
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKILNIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSLFP
CCMFAAE----CAEYSKHVVALTWV--NQKVKCTSNFKVSASPLLYTLIEKTM-QDVSIY
LITK---MY--DL-IFLSKVRYRSDNNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKELVE----KIPELNKAARAAAEVAGQLVIKLTHDVELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLEDLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDTDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENADNNTKA----NGTKPKRCNGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----VR---EEPEEGFPAAS-RLYWDDLKRKL
SEKLDTTDFTSTIKLLNENSYVPREAGSQKDENLALYIENQLREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNATGVLIYMDRT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPA
DWKTDST-CKMVTS-----ENKSVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 745)

NIFG-VIKG----------FVE
PDHYVIVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKELVE----KIPELNKVARAVA

ENSGT00550000074421_2_Linker_1_2 (745, 790)

EVAGQFVIKLTHDVELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLENLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEEIVENNVKG-NHASVKKPKRLNGCICYGTIAVII-FFLIX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX------XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXWLGESSYTPREAGSQKDETLAFLIENKFREFKLSQVWHDEHFVKIQ
VKDSS---RNSVTILR--TSGDAPFLLENPDGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKAKTVTGKLVHANFGTKKDFEEL
N---FPVNGSLVIVRAGKITFAEKVANAERFNAIGVLIYMDRA-DFPVVE----AELPLF
GHAHLGTGDPYTPGFPSFNHTQFPPSESSGLPNIPVQTISRACAEKLFK--DMEE-ECPT
SWNAESS-CKLKMI-----KDKIIKLSVNNVLSERRIFNILG-VIKG----------FEE
PDRYVVVGAQRDAWGPGAA-KSSVGTALLLELSRIFSDMVLKGGFKPRRSIVFASWSAGD
LGAIGATEWLEGYLSSLHLKTFTYINLDKAVLGTKNFKVSASPLLYSLIEKTM-KDVKNP
TTGL-SLYQ--DS-NWINKVEKFSLDNAAFPFIAYSGIPAISFYFCDD-KDYPYLDTTMD
TYDVLNK----RIPQLNRMICAAAEVAGQLLIKLTHDAELNLNYEMYNDKI

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 910)

LSFVRDMNQ
FRGVIKEMGLNLQWLYSARGDFVRATSRLTTDLKNAEKANKFVMRAINDRIMKVEYNFLS
PFVSPRDSP----FRHIFWGSGSHTPSALLENYKLRQISGGTFNDTLL-TQLALATWTIQ
GAANAL-GDIWDIDNEL--------

------------------------------------------------------------
-----------------------------------RMAQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENVDNNMRP----IVTKPKKFNGTVCYATIAIII-FFVIA
FQE-SLKFCTFVKCQSNCVFFLPSFSLSP---SF--SFSSLTFFLPLP-FLLYCILKLNL
SSFKKR---FSFSRLLGESSYVPREAGSQKDESLAYYVDNQFNKFKLSKVWRDEHFVKIQ
VKGSN--AENSVTVTD--TSGNVVFMMDNPEGYVAYS

PF02225 // ENSGT00550000074421_2_Domain_0 (338, 421)

KATTVTGKLIHANFGTKKDFEDL
K---TPVNGSLVIVRAGEITFAEKVANAERLNAIGVLIYMDQT-KFPIVN----AELPFF

ENSGT00550000074421_2_Linker_0_1 (421, 544)

GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTITRACAEKLFN--HVEN-DQTL
RWRFNFR-LS--AD-----LSESILVYISNQVTDIKMLALLGGYIKGQ--------VASP
DDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 712)

YIVVGAQRDAWGPGAA-KSSVGTALLLQLAQMLSDMVLKDGFRPSRSIVFASWSGGD
FGAIGATEWLEGYLYSLHLKAFTYINLDKAVLGTKNFKVSASPLLYTLIEKTM-RDVKHP
LTGQ-SLYQ--DS-NWMSKVEMFSYDNAAFPFLAYSGIPAVSFCFCENNAD

ENSGT00550000074421_2_Linker_1_2 (712, 789)

YPYLGTFSD
TYEELIQ----KIPDLNKMARVAAEVAGHFIIKLTYEVELNLDYERYNSKMLSFVKDVSQ
FRADVKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLSLQWLYTARGDYFRATSRLTTDFKNAETTDRFVMREINDRIMKVEYHFLS
PYVSSQDYP----FRHIFWGSGPHTLSALIENLKLRRENSAAFNETLLRNQLALATWTIQ
GAANALSGDIWNIDNEF--------

------------------------------------------------------------
------------------------------------MDQARSAFSNLFGGAPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENVDNNVRS-NHASLTKPKRFNGSFCYAVIAVII-FFLIG
FMIGYLGYCKRVEPKSECGRSGD--SKEI---EGTEPPETEEYFPETPSRLLWTDLRTML
SERLTATEFTNTIKRLNGNSYVPREAGSQKDESLAFFIENQFREFKLNKVWRDEHFVKIQ
VKGSN--AQSSVTVVN--GSGDMISLVENPTGYVAYS

PF02225 // ENSGT00550000074421_2_Domain_0 (338, 422)

KATTVTGKLVHANFGTKEDYEAL
S---YPVNGSLVIVRAGEITFAQKVANAESLNAVGVLIYMDQA-KFPIVN----ANLPVF
G

ENSGT00550000074421_2_Linker_0_1 (422, 544)

HAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEALFA--NMKG-DCPS
SWKTDSS-CRLEFP-----GDKNVKLTVNNELKEIRIFNVFG-VIKG----------FEE
PDR

PF04389 // ENSGT00550000074421_2_Domain_1 (544, 724)

YVVIGAQRDAWGPGAA-KSSVGTALLLELARIFSDMVSKGGFKPSRSIVFASWGAGD
FGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGAKNFKVSASPLLYSLIEKTM-QEVKHP
VTGL-SLYR--DS-NWINKVEKLSFDNAAFPFLAYSGIPALSFCFCED-TEYPYLGTTMD
TYE

ENSGT00550000074421_2_Linker_1_2 (724, 789)

VLSQ----NVPELSRLTRAAAEVAGQLLIKLSYDVELNLNYDMYNDKILSFVKDMNQ
FRADIKEM

PF04253 // ENSGT00550000074421_2_Domain_2 (789, 908)

GLNLQWLYSARGDFFRATSRLTTDYKNAERANRVVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGSGSHTLSALLEHLKLRQKNSGAFNETLLRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSTFSNLFGGEPLSYSRFSL
TRQVDGDNSRVEMKLAAEE-DDIDNNVRG-NRAH-AKRKRLNGLICCGTTAVII-FFLIG
FLIGYLGYCKRVEPKTECEQTESAAVE--------TEEETEEDLPEVSPHLFWSDLKAML
SEKLNSADFTKTIRQLNENSYVPREAGSQKDTNLAFYIEDRFRKLQFSKAWHNEHFVKIQ
VKSSS--DPNSVTVIA--MNNGGPYLLENPQGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKATTVTGKLVHANFGTKQDFEAL
S---TSVNGSLVLVRAGKITIAEKVANAESLNAIGVLIYMDHT-KFPIVD----AELPLF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEKLFDSKNMEG-DCPS
SWKTDSS-CKLVTT-----QNRNVKLTVNNVLKEIRIFNVFG-VIKG----------FEE
PGHYIVVGAQRDAWGPGAA-KSSVGTALLLELAQIFSDLVFKDGFKPRRSIVFASWSAGD
FGAVGATEWLEGYLSSLHIKAFTYINLDKAVLGTSNFKVSASPLLYSLIEETM-QDVKHP
VTGL-SLYR--DS-NWMNKVEKFSLDDAAFPFLAYSGIPAVSFCFCGA-SDYPYLGTTQD
TYEVLNQ----EVPELNKMARAAAEVAGQLMIKLTHNAELNLNYDMYNEKM

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFVRDMNQ
FKTDVKEMGLSLQWLYSARGDFYRATSKLTTDYKNSDTADRLVMREINDRIMRVEYHLLS
PYVSPRDAP----FRHIFWGSGSHTLQALLEHIKLRRQDRSAFNETLFRNQLALATWTIQ
EAANAISGDIWDIDNEF--------

------------------------------------------------------------
------------------------------------PPRRARKLFLNFGGEPLSYTRFSL
ARQVDGDNSHVEMKLGVDEEENTDNNTKA----NGTKPKRCGGNICYGTIAVII-FFLIG
FMIGYLGYCKGVEPKTECERLAGTESP-----AR---EEPEEDFPAAP-RLYWDDLKKKL
SEKLDSTDFTSTIKLLNENLYVPREAGSQKDENLALYIENQFREFKLSKVWRDQHFVKIQ
VKDS---AQNSVIIVD--KNGGLVYLVENPGGYVAYSKAAT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
D---SPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDRT-KFPIVK----ADLSFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAAAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFG--NMEG-DCPS
DWKTDST-CKMVTS-----ENKNVKLTVSNVLKETKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 725)

NIFG-VIKG----------FVE
PDHYVVVGAQRDAWGPGAA-KSSVGTALLLKLAQMFSDMVLKDGFQPSRSIIFASWSAGD
FGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTM-QDVKHP
VTGR-SLYQ--DS-NWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCED-TDYPYLGTTMD
TYKE

ENSGT00550000074421_2_Linker_1_2 (725, 790)

LVE----RIPELNKVARAAAEVAGQFVIKLTHDIELNLDYERYNSQLLLFLRDLNQ
YRADVKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LSLQWLYSARGDFFRATSRLTTDFRNAEKTDKFVMKKLNDRVMRVEYYFLS
PYVSPKESP----FRHVFWGSGSHTLSALLESLKLRRQNNSAFNETLFRNQLALATWTIQ
GAANALSGDVWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMNQARSALSNLFGGEPLSYTRFSL
ARQVDGDSSHVEMKLAVDEEENTDNNMRP----DVRKPKRFNGNICA-IIAVIL-FFFIG
FMIGYLGYCKGVEPKAECERLAATESP-----EM---DEPEEDFPRTPSRLYWADLKTKL
SEKLDTTEFTSTIKLLNENSYVPREAGSQKDENLAFYVENQFNEFKLSKVWRDEHFIKIQ
VKGS---AQNSVTVTD--LNGTMVFTLDYPEGYVAYSKATT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLIHANFGTKKDFEDL
N---SPVNGSLVIVRAGKITFAEKVANAESLNAIGVLIYMDHT-KFPIVE----ADVPFF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRACAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LFE--YMEG-DCPS
DWNIDSS-CKLRSS-----QNKNVKLTVNNMLKEIRIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 732)

NIFG-VIKG----------FVE
PDRYIIVGAQRDAWGPGAA-KSSVGTTLLLKLAQIFSDMVLKDGFKPSRSIVFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKAVLGTKNFKVSASPLLYTLIEKTM-QDVKHP
LTGL-PLYQ--DS-NWVNKVEKLSFDNAAFPFLAYSGIPAVSFCFSED-TDYPYLGTTKD
TYKILTE----

ENSGT00550000074421_2_Linker_1_2 (732, 790)

RVPHLNKMAQVAAEVAGQFMIKLTHDVELNLDYERYNNKMLSIVRDLNQ
FRADIKEMG

PF04253 // ENSGT00550000074421_2_Domain_2 (790, 906)

LNLQWLYSARGDFFRATSRLTTDFRNAEKTDRFVLREINDRIMKVEYNFLS
PYVSPQDYP----FRHIFWGSGPHTLSALIENLKLRQENNGAFNETLLRNQLALATWTIQ
GAANALSGDIWDIDNEF--------

------------------------------------------------------------
-----------------------------------MMDQARSAFSNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAADEEENVDNNTMG-NHTSVTKPRRLNGYICYGTTAIII-FFLIG
FMIGYLGYCRRAETKAQCERPAGTESPAQ--------KEPEEHLPETP-RLFWADLKSML
SERLDTTDFIGTLKMLNGNSYVPREAGS-KDESLAFFIENQFREFKLXXXXXXXXXXXXX
XX---XXAQNSVIIVD-SSSGSLIHSVENPEGYVAY

PF02225 // ENSGT00550000074421_2_Domain_0 (337, 435)

SKTTTVTGKLVHANFGTEKDFEDL
N---TPVNGSLVIVRAGKITFAEKVANAERFSAIGVLIYVDQT-KFPVVN----ANLPVF
GHAHRGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAEKLFE--NMEG-DCPS
SWRTDSS-CKLESS-----ESKSVKLTVNNVLKEIRIFNVFG-VIKG----------FEE
PDRYVVIGAQRDAWGPGAA-KSGVGTGLLLKLAQILSDMVLKXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXX
XXXX-XXXX--XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXX----XXXXXXXXXXXXXXXXXXXXVVELHDVELNLNYEMYNDKI

PF04253 // ENSGT00550000074421_2_Domain_2 (772, 909)

LSFVKDMSQ
FRTDIKEMGLSLQWLYSARGDFFRATSKLTTDYKNAERTNRFVMREINDRIMKVEYHFLS
PYVSPRESP----FRHIFWGFGCHTASALLEHLKLRRKNSGAFNQTLLKNQLALATWTIQ
GAANALSGDIWDIDNDL--------

------------------------------------------------------------
-----------------------------------MMDQARSAISNLFGGEPLSYTRFSL
ARQVDGDNSHVEMKLAVDEEENADSNMRA----SVPKSKRFNGSICYGTIAVII-FFMIG
FMIGYLGYCKRVEPKTDCGKSGTGVEESE-----NS--EAEEDFHETPSRLYWADLKAML
SEKLNTIDFTSTIKQLNQNTYIPREAGSQKDENLAYFIENQFHDFQLSKVWRDEHYVKIQ
VKGSH--AQNSVILLN----NSLAYLLENPKGYVAYSKATT

PF02225 // ENSGT00550000074421_2_Domain_0 (342, 467)

VTGKLVHANFGTKKDFEDL
N---VSVNGSLVIVKAGKITFAEKVANAESANAIGVLIYMDQA-TFPVLK----TDLAVF
GHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRECAEK

ENSGT00550000074421_2_Linker_0_1 (467, 519)

LLA--KMEN-DCS-
GWKTDSS-CKMQFP-----ENMSVKLSVNNVLKEIKIL

PF04389 // ENSGT00550000074421_2_Domain_1 (519, 726)

NIFG-VIKG----------FEE
PDRYIVVGAQRDSWGPGAA-KSSVGTALLLELARTFSDMVLKGGFKPSRSIIFASWSAGD
FGAVGATEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYRLIEKTM-QDVKHP
LTRL-SLYQ--DS-NWINKAEQLSFDNAAFPFLAYSGIPAVSFCFCEN-GNYPYLNTDMD
TYDVL

ENSGT00550000074421_2_Linker_1_2 (726, 791)

IK----EVPQLDKMMRTAAEVAGQFMIKLTHDIELNLDYEMYNNKLFSFVRDLNQ
YRADIKEMGL

PF04253 // ENSGT00550000074421_2_Domain_2 (791, 906)

SLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLS
PYVSPRDSP----FRHIFWGSGSHTVSALLENLKLRQKNNGAFNETLFRNQLALTTWTIQ
GVANALSGDVWNIDNEF--------

------------------------------------------------------------
-----------------------------------MMDHARSAISNLXXXXXXXXXXXXX
XXXMDGDSSHVEMKLAAEDEDSGESNIENN----TTSSKRNGGNICFGIIAITI-FFLIG
FMVGYLGYCKQLETNVKCKFGRTEHSGRDDSPE--------DL--PGAPALSWNDLKKLV
SERIXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXX---XXXXXXX---XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXVANAQAYEAVGVLIYLARS-DFDIIE----ADVVPF
GHAHLGTGDPFTPGFPSFNHTQFPPSQSSGLPNI-VQTFSRXXXXXXXX--EMQGEDCPP
SWIGDSS-CKISSKVN-------VRLTVNNVLEERKLLNVFG-VVKG----------IDE
PDRYVVIGAQRDAWGPGVA-KSLVGTSLLLEIARAYSSLVSKXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXGYLTTLHLKAVTYINLDTAVVGSSNFKVSASPLLYTLMEKIM-KEXXXX
XXXXXXXXX--XX-XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXSKPYRYLDTKLD
TYDRLIN----EIPQLEGLMSAAAEVAVQMVIRLTRDHELYLDYERYNEELFNF

PF04253 // ENSGT00550000074421_2_Domain_2 (775, 909)

VRKLLV
YKSELKSLNLNFQWMFSARGDFSRATHDLTNDLYRSDTANRLVNREINDRIMKVEYSLLS
PYVSPKETP----FRHIFWGSGSHTLSALLNHLQLLKNKDSNFNETLFRNQLALATWTIQ
GAANSLAGNIWDIDNEF--------