Query Results 

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDTGSQKEES-----------------FIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSKVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHR--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKQ---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLSESP---------------EKQQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGARIPDSV-RDGLAYRGRVFL-ELVTQIKSCQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNIKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLC

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIQTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDTDINKSQVLEEVYENQGRDI
RGAWGPAAIPNTDVNGQPTEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLQL-GPA--EG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLMKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLATWDGDGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPS--------------TFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDY

PF00168 // ENSGT00550000074414_4_Domain_9 (2185, 2230)

IWSLDATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFIWLRSPVQHFCSVF
WKRYRFKLIAFMVISILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTTDHEWKLHPGPTNHLSNIFPELPAPED-

------------------XXIIPLGIFTDMKKKTRVEEGNDPIWNEVHTLWRSWKRTEL-
---LQE--QRAG------------------------LGTKQVPIST--------------
SAFRLPAFALQCTVTLQVAQ---------------IRDQ--------------DTRTTGN
EEFLSSTADKMTQQKLMMPSF-TMHRALASKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 299)

QVRLKVFEARQLLGNNIKPVVKMNI
AGHQHLTRIKTGNNPFFNEIFFQNFYE-VPAKFFEENILIKVVDSAASRSKAEIGRFQVR
KL--YGDPPWV---PGLGLGKSTWHFTQILSWICLPTWRGVEVGDPS-------------
----------------N-----------LLHVLGK-------------------H

PF00168 // ENSGT00550000074414_4_Domain_3 (416, 492)

HSAAP
ALEVELIGDKLRTYPQN-QNDSPIWNQILTFQIQLPCLSSYIKFRVVDCSRRDCWEEIGS
ASLCLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 734)

GEEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKAPFRT-P-EEGTCILDAV-KDGLTYQGRIFL-EIITRMKSQQDSV-IKDL---SREV
AQI---ERQQYRQKYGLCVIFLSCTMMPKFKDLIQFEVSMG-HYGNKMDPNYKPLVSTTQ
---HSPVIFDG--TIYHYVPWYDMKPVVAVTSNWEDVSFRMNCLNLLHITRDHLKTNLDI
LKSI-RNPKD-PA

PF08165 // ENSGT00550000074414_4_Domain_4 (734, 785)

LLQQWEKLLKDLIEDCRRPLPCMDD-QPKANNLDKNKWQLRNYLLQQ
LAWK

ENSGT00550000074414_4_Linker_4_5 (785, 832)

AKGA----KPRNMVVTAEDWLH-----------------RLNSVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VMIWLMSKQQRVAYARVPAHTVLFSPEGPLSSGKFCGKIQNLLLQSPEG---------EG
Q-DTLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVIHSKNLKLLQQGNMVVYAET---YENQAKLRDQWGQQGLHNC
PNFSDVLGRKAVPKTDFKAPLGWHWQGDWIVEPQRRLLLDTDINKSQVLEEVYENQSRNA
TGIWVPAAIPNTDVNGRPVEALENVKCPQGWHFKRSWIVELNRAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHTCRRRRWVRVRFRNHKE----LSQE-QETLSFLQMQGMS--EE-GKG
GWEYGTF-DSKFHLDPKPTSQFRRRCWHRRLVPNKDRGVAPIFFLEGSLAVELE------
-------------------------------NQ-L--KKEGDKTRPWQ--H-WKDSWRHI
--------QEDP-RIPTMPFIFC-ILNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1381)

QLFCYIYGARNLMYN-----QILTFQEP
FIRVVFLNHSLCTQTLRS---SAAPTWAQTLIFQHLLLFENPKDTRENPPLVVLELWQHD

ENSGT00550000074414_4_Linker_6_7 (1381, 1574)

SKG-NKVLWGRSMWPPVVWLNLQG---------------WTFTPLRWHPLVKELGEEEGE
ILASCELILETEKL---------------K-DMSLPILSVPCKNGIYTLPKNIQPTLRMM
AIE---------------------------------------------------------
---------VMAW

PF00168 // ENSGT00550000074414_4_Domain_7 (1574, 1664)

GLRNMKK-----VSYPQLLVGCGEESLRTEPISNYQENPNFPTSNFF
L------TVFMPLEETHALPLVVKVVDNQVYGQEVVVGQANID

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWALN----
---------------YTPIKLPT--LSVKKPD-----TFLDFLYK--KFWFDSRKDEDDY
D--HDVDWWSKFF--WATSDAD---KSLTYKYKSYHTLKVYDCELEAVPDFQGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPDAPIPPRQFSSWPETGNFPQMCM

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYY--PNTLDPIFGTMYELTCNIPLEKD
LEIQLYDFDLITSDDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2126)

LLSGFGARCGLSKSYCKSGP--FRWRDQLTPSH
LLDRYAKQKG-LPPPVFDLENDSVFYNGKDFQLQSFEPTPPTFEGLGPKKERLALYILNT
QGLVPEHVETRTLYSNSQPGIDQGKIQMWVDIFPKKLGPPGSPVNISPRKPK--------
-RYELRCIIWRTTQVDLVRRTLSRE

PF00168 // ENSGT00550000074414_4_Domain_9 (2126, 2235)

KMSDIYV-KGWLFGLEKDMQKTDVHYHSLTGDAIF
NWRFIFTMDYLATERVCVQSQKDYIWSLDPTSMKFPARLIIQIWDNDFFSPDDFLG--VL
ELDLSDMPLPAVKS

ENSGT00550000074414_4_Linker_9_10 (2235, 2278)

KQCSLKMMETDSQWPY-VHQKHISIFKKTNVTGWWPCQVHD-G

PF16165 // ENSGT00550000074414_4_Domain_10 (2278, 2373)

DKW
RLSGKVKMTLEILPEREALIRPAGRGQSEPNQFPKLHPPVRNDSSFLWYQSPIKNFCYVF
CKRYRSKIICLVLILVIGTILFNFIYSAPNYLAMALIKPQLRVKPPIKIV-NIIGSVNTS
SINSSIFKMKG----------SKLYPLKDKRPIFLQGPRNHVKDVIPEI------

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--------------------------APRGRILLLELSTHTRSPDGRQ-QDT--IASEDV
ARVQRL--LPRRRRFGLCGVFYSATMLAPAPELLRFELSIG-NYGDTGDTLSPPVPLPGH
HGGADPAADTG--NRYHYLPWYDAKRW--------------DAANLLQNMAQRLEGNVAA
LWWDVEGNPA-PA-ELHWGNLGGEMGLEGKKRKRHLWG-----GKVTSLGWKSDNSVVNR
----------------HTSGLETWHFGAKRGSSVGKHPRVALQVLEAQIPKTPLDAELRA
ARLHLLRLMAAS

PF08150 // ENSGT00550000074414_4_Domain_5 (853, 887)

ACARVPAHCLVFSPRGRAACGRLCGRTQTLFLGCPINVTS--------
LSLSHPIHVSLCVPSMSPPGHFHIHLC------HSLSHQCHYENQTKLLGKWSGRGLPGR
PGFSDITGKAGLPRHRIRPPKGWRWDGDPALVPVPRLLLDAEANLGEVLEEVYENESRQP
GGAGG-LPAANTDAAGAAVPPKEEVACPQGWHITDSWRVDMAGAVDEAGWEYGASTAPGS
PPLAWHPAEKTYHTHRRRRWLRTRRTPP--------------------------------
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-LRLVVESARIEPPLS

PF00168 // ENSGT00550000074414_4_Domain_0 (17, 109)

PPPRPCLTVYFRDIKKRTRVVEGNDPTWNET-LIWHLWSRPLEN
DSFLQVILRDMGSKKKE-----------------RFIGLATVLLKPLV

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KKPREVLFVKDL
ILLNHSMMPTDCTVSLQVAH---------------VMPR--------------DTEKEGG
GDPLGMTTRELAQGKLMVPGSAGLHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 301)

QVRVKVFEARQLMGNNIRPVVKVTI
AGQQYHTRIKMGNSPFFNEIFFQNFYE-VPAKFFDEIILVQVLNSSVMRSKAEIGRFQTD
IGFVYHSPGHTLLRKWLGLCQPNAPSSGVRGYLKV-TICALGVGDQALVDQKL---PYRA
-DMDIEVFKSTAVPT-TMAYLQLFIYCAEDLRGAE-------------------------
-------RGHP

PF00168 // ENSGT00550000074414_4_Domain_3 (432, 493)

RTNVRP-QTDNPIWNQILTFQIQLPCLSSYIKFRALDCSRSDCWAEIGT
ASLSLGHISSSG

ENSGT00550000074414_4_Linker_3_4 (493, 738)

EEIGG-------------------------HFLGFLPCFGPSFLPLHG
GPKAPLRI-Q-EEGTSVPDAI-RDGLSYRGRVLL-ELITQIKSHQHTM-IKDL---SQEV
ARI---EKHQNRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSSWEDVSFRMHCLNLLQFARDRLKANLDV
LKSM-RNLRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 786)

WEKLRRELVEDCRRPLPCMAD-QPKATNLDRKRWQLRSLLLQD
LARKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KEA----KPRDMVATVEGWLH-----------------CLNSVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--SLPD
VMIWLMAKEQRVAFAQVPAHTILFSRAGPLHCGRFCGKIQTLLLQYPEG---------EG
QQDMLPAHLRVCMWF

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGNMVVYLET---YENQAKFKDQWGQQGLYHC
PNFSDVTGHKALPKSKFKVPSGWHWQDSWKVEPQRRLLLDIDINKSQVLEEVYENQERNF
SGSWVSSAIPNTDVNGQPMEARDTVRCPQGWHFKKNWAVELNHSVDSEGWEYGVGIPPSG
LPRLWTSVEKNYHSCRRRRWVRMRFRDHG----ELGGE-EQTVSFLQMQGLV---SEGEE
GWEYGSF-GSKFHLDPQPQSRFRRRCWHRRLAPNKNTSVAPIFLLEGSLATDLKQ-----
-----------------------------------NPKKEENRALPWAQ---FRDAWKPA
--------QEDP-RLPSMPFIYC-TLDKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSN-----QVLAFQGP
FVRAVFLNYSQCTQRLPS---SVAPIWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1574)

QHLLLHESPQDTRESPPLVVLELWQCD
ALG-KESLWGRSMWPPVVWLDPQD---------------WMLPPLRWHPLVKERGEEEGE
ILASCELILETEKL----------------REKHLPLLSIPWKDGVYTLPKSIQPTMRKT
AIE---------------------------------------------------------
---------ILAW

PF00168 // ENSGT00550000074414_4_Domain_7 (1574, 1664)

GLRNMKQ-----ARHPQLLVEFGGESLRTEPIKDFPTNPNFPESVLL
L------MVFMPKEEVYSEPLVLKVLDNQDFGRQIVLGQASVD

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWARD----
---------------YLSGLLTS--PYLPPAF-----QVLGFLYE--KFWFKSSRPEDEY
E--HEVDWWSKLF--WATGDD----KSLQDKYQDYHTLKVYDCELEAVPDFQGLEDFCQT
FKLYQEQPKVDSPVV-GEFKGLFRIYPFPENPEAPKPPRQFLTWPEREDFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVVLKLGSMKLGSRDAYK--PNTVDPIFGMMFQLTCTIPLEKD
LQIQLYDFDLFSFDDEIGSTFIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPVFDPDGDSVFYRGKKFKLQSFESKAPTMPGLGPKKERLALHILHT
QGLVPEHVETRTLYSESQPGIDQGKVQMWVDIFPQKLGPPGPPVKISTRKPK--------
-RYELRCIVWKTTQVDLVDEALSREKMSDIYI-KGWLFGLEKNMQKTDIHYHSLSGEATF
NWRFIFTMDYLAAEHMCVESQKDYI

PF00168 // ENSGT00550000074414_4_Domain_9 (2186, 2232)

WSLDPTSTKFPARLIIQIWDNDIFSSDDFLG--VL
ELDLSDMPRPA

ENSGT00550000074414_4_Linker_9_10 (2232, 2278)

RHAKQCSLRMLDAKPKWPF-LPHEHFSLFKKKTVTGWWPCQVQD-G

PF16165 // ENSGT00550000074414_4_Domain_10 (2278, 2372)

DKW
RLSGKVKMTLEVLSEKEASARPAGQGQSEPNQYPTLHPPLRAGSSFMWLRSPVRHLCLSL
CRRYRCKILSFSVLLVIAFMLFKFIYSAPNYLAMSWIHPAIRMEPPIKIY-NLITSATAS
TASPAPLATQA----------PSLEPVTDHQLPILQAP-----------------

MLR

PF00168 // ENSGT00550000074414_4_Domain_0 (4, 110)

LIVQSAKISPPLSPPPRPCVSVYFRGKRRVL-----TSPWLPQT-LIWHLWNHPLQK
DSFLQITLRDMGSMKKE-----------------RFIGMATVLLKTLVK

ENSGT00550000074414_4_Linker_0_1 (110, 216)

KPRKILFVNDL
TLLNHSMMPTECTVTLQAAL---------------MTYK--------------DIEKIGD
EDLLAITAQEVAKQKLMFPSA-TVHKALSPKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 283)

QVRVQLFEARQLMGNDIKPVVKVVI
GGHQHHSRIKMGNNPFFNELFFQNFYE-APMKFFDEIILIQVRSQARQRSREDGGNWRLV
SHRPSASPGHTLLRKWLGLCQPNEPNSGVRGYLKV-TICALGVGDQAPVDKKL---IYRV
DDTDTRIFKSSVVPI-SIA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLKK-------------------HYSVSP
ALEVELIGEKVTRTRPS-G---QAPTAPLTCPLQLPCLSSYVKFRVLDCPRNRCNDEIGT
VSLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GAEIEG-------------------------MYSGFLPCFGPSFLTLRG
GKKAPFRM-K-EEDPNIPNIV-KDGLAYRGRVFL-EKKDP--------------------
---------LYLPLYGLCVIFLSCTMMPDFKDLIQFEVSIG-HYGNKMDLSYKPLVSTTQ
---YSPAIYDG--NIYHYVPWYNTKPVVAVTSFWEDVSFRMNCLNLLQFTRDRLKANLDT
LKSM-RNPRD-PALLP

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTS-QPKATDLDKNRWKLRRLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----PPRDMVATAEGWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--NLPD
VMIWLMSREQRVAYAQVPAHSVLFSPDGARHSGRFCGKTQTLFLQYPEG---------EG
EKDTLPGQLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSRDLELLRQGEVVVYAET---YENQAKFKGQWGQQFLQHC
PNFSDVLGHKALPKEDFKEPHGWHWDGPWTVEPQRRLLLDTDINKSQVLEEVYENQRRDA
VGAWVPAAIPNTDVNGEPVEAREIVQCPQGWHVKQTWAVELNHAVDNEGWEYGVGIPPSG
LPKVWNSVEKTYYSRRRRRWARVRYRDHGQ----LSHE-QETLSFLGLQTVTAGTTGWEG
GWEYGVF-GSKFHLNPEPQSRFRRRCWHRRLAPNKVKGIAPIFLLEGSL-----------
----------------------------------------------VKLDR-IMSSRRAP
--------PGIT-QTPSLPFIYC-VFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSSRV-----QTFQGP
FIRLAFLNYSQCTQSLKS---SAAPTWAQTLTFQHLLLYESPQDTRDSPPCVVLELWQRD
PQG-SETLWGRSMWHPVVWLDAQD---------------RILPPMRWHPLVKGLEDEEGE
ILASCELILET----------------------ELPMLSVPWKDGIYILPKSIQPTLRKM
AIE---------------------------------------------------------
---------MLVWGLRNMKQ-----VRSPRLLVECWEECLQTEPIRDFQTNPNFAQSALL
L------TLYMPTEETFALPLVLKVVDSQDFGQETVVGQANVHSLQPYFCDPWAED----
---------------YVPPIL----------K-----SPDGYLCE--KFWFKSSKDEYDQ
E----VDWWSKLF--WATGDAP---QTLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEWPRLDSPVV-GEFKGQFRVYPFPENPEAPKPPRQFPLWPKKEDFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

IRVYM
VRAFHLQPQDLNGLCDPYVILKLGQTMLGNRDKYQ--PNTLDPIFGVMFELSCTIPLEKD
LEIQLYDFDLFSPDDMIGTTVIDLEDRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSL
LLEHHAKRKG-LPPPLFSPEGDSVYYNGKKFELQSFELKPPRARFLGSKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIGPRKPK--------
----------------------------------RWLFGLEKDMQKTDIHYRSVTGEGIF
NWRFTFTLDYLAAEHVCVLSEKVTC-------PGFPGKCL--------LADALSLGSGVL
ELDLSDMPLPAPHSRLCSVRMLEADPKWPHFLQHKHSSLFKMKNVAGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEILTEKEALIKAAGRGQSEPNQYPTLHPPLRTHTLFMWFRSPIGKFIRVV
WRRYRFRIIATAIILLIGLLLFNFIYSAPNYLAMSWIKPELRLNAPIQIYANIINAPNTS
SSLKQLLA-PQ----------N---------------------------------

MLRLIVQSAKISPPL

PF00168 // ENSGT00550000074414_4_Domain_0 (16, 100)

SPPPRPCVSVYFRDVKRTTREVEGNHPVWNET-LIWHLWNHPLQK
DSFLQIALRDMGSMKKE-----------------RFIGM

ENSGT00550000074414_4_Linker_0_1 (100, 218)

ATVLLKPLVKKPRKILFVNDL
TLLNHSMMPTECTVTLQAAL---------------MTYK--------------DIEKIGD
EDLLAITAQEVAKQKLMFPSA-TVHKALSPKPQHFQV

PF00168 // ENSGT00550000074414_4_Domain_1 (218, 297)

RVQLFEARQLMGNDIKPVVKVVI
GGHQHHSRIKMGNNPFFNELFFQNFFE-APMKFFDEIILIQVMNSSVMRFNAEIGR

ENSGT00550000074414_4_Linker_1_2 (297, 300)

FQT

PF08151 // ENSGT00550000074414_4_Domain_2 (300, 358)

D
IGFIYNCPGHTLLRKWLGLCQPNEPNSGVRGYLKV-TICALGVGDQAPVDKKL---I

ENSGT00550000074414_4_Linker_2_3 (358, 382)

YRV
EDTDTRIFKSSVVPI-SIAYL

PF00168 // ENSGT00550000074414_4_Domain_3 (382, 481)

QFFIYCAEDLHLKK-------------------HYSVSP
ALEVELIGEKLKTNVQT-QTESPIWNQILTFRIQLPCLSSYVKFRVLDCPRNRCNDEIGT

ENSGT00550000074414_4_Linker_3_4 (481, 738)

VSLSLNQISSTGAEIEG-------------------------MYSGFLPCFGPSFLTLHG
GKKAPFRM-K-EEDPNIPNIV-KDGLAYRGRVFL-ELITHVKSRQEAK-MKDL---SLDV
ISV---EKHQNRQKYGLCVIFLSCTMMPDFKDLIQFEVSIG-HYGNKTDLSYKPLVSTTQ
---YSPAIYDG--NIYHYVPWYNTKPVVAVTSFWEDVSFRMNCLNLLQFTRDRLKANLDT
LKSM-RNPRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 786)

WERLLRELVEDCKRPLPCMTS-QPKATDLDKNRWKLRRLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----PPRDMVATAEGWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--NLPD
VMIWLMSREQRVAYAQVPAHSVLFSPDGAQHSGRFCGKTQTLFLQYPEG---------EG
EKDTLPSQLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1319)

GNVTDSRDLELLRQGEVVVYAET---YENQAKFKGQWGQQFLQHC
PNFSDVLGHKALPKEDFKEPHGWHWDGPWTVEPQRRLLLDTDINKSQVLEEVYENQRRDA
MGAWVPAAIPNTDVNGVPLEAREIVQCPQGWHVKQTWAVELNHAVDNEGWEYGVGIPPSG
LPKVWNSVEKTYYSRRRRRWARVRYRDHGQ----LSHE-QETLSFLQLHH--PGLAEDEA
GWEYGVF-GSKFHLNPEPQSRFRRRCWHRRLAPNKVKGIAPIFLLEGSWGLHMKE--QAR
REVD-------------------------------------MVSSTRRLDR-VMSSRRAP
--------PGIT-QTPSLPFIYC-VFNRGGGWVRWCQSEERRASLSSSKAPPPQLLPP

PF00168 // ENSGT00550000074414_4_Domain_6 (1319, 1386)

GP
FIRLVFLNHSQCTQTLKS---SAAPTWAQTLIFQHLLLYESPQDTRDSPPCVVLELWQRD
PQG-SETLWGRSMWHPVVWLDAQD---------------RILPPMRWHPLVKGLEDEEGE
ILASCELILETESL-----------------RQQLPMLSVPWKNGIYILPKSIQPTLRKM
AIE---------------------------------------------------------
---------MLVWGLRNMKQ-----ARSPRLLVECWEERLQTEPIRDFQTNPNFAQSALL
L------TLYMPTEETFVLPLVLKVVDNQDFGQETVVGQANVHSLQPYFCDPWAED----
---------------YVPPRPPT--LSVKRYQ-----ELLGYLCE--KFWFKSSKAEE--
--------WSPLAGPWPAAPTS---GV------LRALPQVYDCELEAVPAFQGLQDFCQT
FKLYQERPRLDSPVV-GEFKGQFRVYPFPENPEAPKPPRQFPLWPKKEDFPQQCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYM
VRAFHLQPQDLNGLCDPYVILKLGQTMLGNRDKYQ--PNTLDPIFGVMFELSCTIPLEKD
LEIQLYDFDLFSPDDMIGTTVIDLEDRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSL
LLEHHAKRKG-LPPPLFSPEGDSVYYNGKKFELQSFELKPPRARFLGSKKERLALYLLHT
QGLVPEHVETRTLHSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIGPRKPK--------
-RYELRCVIWKTTLVDPKEKSLSYDRINDIYV-KGWLFGLEKDMQKTDIHYRSVTGEGIF
NWRFTFTLDYLAAEHVCVLSEKDYIWSLDPTVTKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2216)

ARLIIQVWDNNIISMDDFLGSGVL
ELDLSDMPLPAPHSRLCSVRMLEADPKWPHFLQHKHSNLFKMKNVAGWWPCQVLD-GGKW
RLSGKVKMTLEILTEKEALIKAAGRGQSEPNQYPTLHPPLRTHTLFMWFRSPIGKFIRVV
WRRYRFRIIATAIILLIGLLLFNFIYSAPNYLAMSWIKPELRLNAPIQIYANIINAPNTS
SANSSNLTTPQ----------QSLKRTTALRLKHLQGHVTHLRDILPELLAPQN-

MLRLVVQSAKID

PF00168 // ENSGT00550000074414_4_Domain_0 (13, 109)

PPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDMGSQKKE-----------------RFIGLATVLLKPLL

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSNQ--------------DIEKTGA
EDHLGITAREAASQKLMVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILIQVVNSSAMRYKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TIYALGVGDQALIDQKL---LYGT
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQLFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITQIKSYQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIG-HYGNKMDLNYKPLVSSTP
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLY

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLRELAEDCKRPLPCMTY-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPKDMVATAEDWLY-----------------RLNTVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAEM---YENQAKYKDQWGQQGLYHC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDT
RGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QETLSFLQL-GLA--KG-EEE
GWEYDTF-GSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDLKYHAG--KEEDSKTWPWGLDR-Q--FRDPQ
--------RQDT-RPPNLPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1572)

QHLLLYENPQDTKESPPLVVLELWQRD
FWG-KESLWGRSVWPPMVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIE---------------------------------------------------------
---------IL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----TVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YMHPKLPT--LSEKKHQ-----DFLGYLYR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYM
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQ--PNTLDPIFGMMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK--------
-RYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEADF
NWRFIFTMDYLAAERTCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIF
WKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIINSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD-

MLRLV

PF00168 // ENSGT00550000074414_4_Domain_0 (6, 109)

VQSAKIDPPLAPLPRPCVSIDFRDVKKRTSVVEGNEPVWNET-LIWHLWNRPLEN
DSFLQVMLQDMGSQKKE-----------------RFIGLTTVLLKPLL

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAY---------------ISNQ--------------DIEKTGA
EDFLGVTARETARQKLMVPGS-TMHRSLSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLMGNNIKPVVRVSI
GGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILIQVVNSSAMRYKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQLNNPSSGVRGYLKV-TICALGVGDQALADQKL---LYGA
DDTDIQIFRSAAVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGKKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRILDCHRKDCPDEIGT
ASLFLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIEG-------------------------MYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITEIKFHQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIHDG--NIYHYVPWYDTKPVVAVTSNWEDISFRMNCLNLLHFTRDRLKVNLDT
LKSI-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 787)

HQWEKLLRELAEDCKHPLPCMTN-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPRDMVATGEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPEGDLHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAEM---YENQAKHKDQWGQQGLYHC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVDPQRRLLLDIDINKSQVLEEVYENQARDA
RGTWGPATIPNTDVNGQPMEARENVKCPKGWHFKKDWAVELNHAVDSKGWEYGMEIPSLG
QRQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QETLSFLKL-GLA--KG-EEE
GWEYGTF-GSTFHLNPQPQSKFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDVKY-TG--KEEDSKTWPLRLDR-Q--FRDPL
--------RQDT-QPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1390)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQHD
SWG-KESLW

ENSGT00550000074414_4_Linker_6_7 (1390, 1572)

GRSMWPPVVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILETEKL---------------R-EKQLPILSVPWKNGAYTLPKNIQPKIKRM
AIE---------------------------------------------------------
---------IL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPHLLVEFGEESLKTEPIRDFQTNPNFPES--V
LVL----TVLMPTEEAYTLPLVVKVVDNWAFGQQSVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YMHPKLPT--LSE-KHQ-----DFLGYLYE--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSPKYEYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDTYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLKRYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPQTPTLHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIKPRKPK--------
-RYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYYSLTGEADF
NWRFIFTMDYLATERMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDTFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDANPKWPYNLQYEHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2373)

LSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLRSPVQYFCYIF
WKRYRFKFLAFMVILIIALMLFNFIYSAPHYLAMNLIKPHLQLSPPIKIF-NIITSVN--
NASSSILPTQD----------PNLKPTIDHEWKLHPGPRNHLSDIFPELPAPQD-

MLR

PF00168 // ENSGT00550000074414_4_Domain_0 (4, 110)

LVVESAKINPPLSPPPKLCVTVYFRDVKKKTRIQEGNDPIWNET-LIWYLWNQPLEI
DSFLQVTLQDEGSRKKE-----------------RFIGTATVLLKKLVQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

KPDEVLDMKNL
VLLNHSMKPTDCTVNLQLAQ---------------MHDQ--------------HTEMMGH
EELLYSTANKVTQQKLMVPGY-TMHRTLTSKPQQF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 301)

QVRIKVFEARQLLGNNIKPVVKINI
AGHQHITRIKIGNNPFFNEIFFQNFHE-VPAKFFEENILIQVVDSAASRSKAEIGRFQTD
IGFIYHAPGHTLLRKWLGLCQKNKTNSGVRGYLKV-TICALGVGDMALVDQKL---PYET
-GTQVKIFKSAAAPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHFRK-------------------HQSASP
ALEVELIGNKLRTHPQS-QSDSPIWNQILTFQIQLPCLSSYIKFRVVDCSKRDCWEVIGS
ASLCLNQISSTGEEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKAPFRI-P-EDGTCIFDAV-KDGLTYQGRIFV-EIITRMKSQQDSV-IKDL---SREV
TQI---ERQQYRHKYGLCVVFLSCTMMPKFKDLIQFEVSMG-HYGNKMDPNYKPLVSTTQ
---YSPVIYDG--CLYHYVPWYDMKPVVAVTSKWEDVNFRINCLNLLHVTRDHL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------YENQAKVKGQWGQQGLYRC
PNFSDVLGRKAVPKTDFKTPLGWHWKGDWIVEPQRRLLLDTDINKSQVLEEVYENQTRNA
KGIWVPAAVPNTDVNGQPVEAMENVKCPQGWHFKKSWIVDHNYAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSSRRRRWVRVRFRDHQE----LSQE-QETLSFLQTQDIS--EE-GKE
GWEYGTF-DSKFHLDPKPTSRFRRRCWHRRLAPNKERGVAPIFFLEGSLAAELE------
-------------------------------NQ-S--KPEPHRTRS------WWDSWRRM
--------QEDP-WIPNMPFIYC-VFQKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1383)

QLFCYIYRARNLMYN-----QILTFQEP
FIRVVFLNHSLCTQTLHS---SAAPTWAQTLIFQHLLLFENPKDTKENPPFVVLELWQHD
SK

ENSGT00550000074414_4_Linker_6_7 (1383, 1574)

G-KKVLWGRSMWPPVVWLNLQS---------------WTLTPLRWHPIMKELGEEEGE
ILASCELILEVE-----------------K-DVHLPMLSVPFKDGIYSLPKNIQPTVKMM
AIE---------------------------------------------------------
---------ILAW

PF00168 // ENSGT00550000074414_4_Domain_7 (1574, 1664)

GLRNMKK-----VRYPQLRVECGEQSLRTDPISNYQQNPNFPIKNFL
L------TVLMPMEETYALPLMVKVVDNQVYGQEIVVGHANID

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWALN----
---------------YTPVNIPP--LPEKKPD-----TFLDFLYK--KFWFDSRKDEDDY
DYEYDVDWWSKFF--WATDNDD---KSLKYKYKNYHTLKVYDCELEAVPDFQGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPEAPNPPRQFSSWPETDNFPQTCM

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKFGSRDSYY--PNTLNPIFGTMYELKCNIPLEKD
LEIQLYDFDLVTSDDEIGMTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2122)

LLSGFGARCGLSNCYCKSGP--FRWRDQLSPSY
LLDRYAKQKG-LPPPVYDLEKDSVFYNGKMVQLKSFESTPPTLKDLGPKKERLALYILNS
QGLVPEHVETRTLFSNSQPGIDQGKIQMWVDVFPFVLGPPGRPVNISPRKPK--------
-RYELRCIIWSTTQVDLVQQT

PF00168 // ENSGT00550000074414_4_Domain_9 (2122, 2233)

FSRDKTSDIYV-KGWLFGQEKDMQKTDVHYHSLTGDAVF
NWRFIFTIDYLVTERVCVQSQKDYIWSLDPVSMKFPARLIIQIWDNDLFSPDDFLG--VL
ELDLSDMPLPAV

ENSGT00550000074414_4_Linker_9_10 (2233, 2280)

SSKQCSLKMMEPDPKWPH-TQQKRISLFKKTNVTGWWPCQVLD-GDK

PF16165 // ENSGT00550000074414_4_Domain_10 (2280, 2372)

W
RLSGKVKMTLEILTEKEALIRPAGRGQSEPNEFPKLHPPVRHDSPFMWIRSPIKNFCYVF
CKRYRYKIICLLMTLLLAMILFNFIYSAPNYLAMAWIKPELRLNPPIKIV-NLISSANTS
NINSSVYREEG----------S----------------KHHVKDVVPGIPAPQ--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------G

PF08151 // ENSGT00550000074414_4_Domain_2 (310, 372)

HVLLSRWLTLYDPNNLNAGLKGYVKV-NLCVLGAGDRVPPREKETDFVDAK
GDTEAMLLRPA

ENSGT00550000074414_4_Linker_2_3 (372, 381)

AMPSGRLVT

PF00168 // ENSGT00550000074414_4_Domain_3 (381, 479)

LQLYVFQAQDMPHMKGDHVNNVRAE------DPTGTSVDS
SLEVNFAGKVLNTKIVF-GDANPVWNQRMSFPMLMPSICDLIKLSAIDGDQSGDGQIL

ENSGT00550000074414_4_Linker_3_4 (479, 742)

GF
AFLSLSQISCSGTEIENKIKLGA--------SAYIRVGLYSKDFSGFQPCFGPSFLTLYG
NPKEFVAQ---GDALEDFRVGAEEGIAYRGRVLV-ELSIKTEKLVVPK-LENI--PEESV
KRIEKITSRTLPKCLGLCDVFSDDACRSQSGGLLQLADR------NFVNVYCFQMPAEIF
---WHGYFFPG--NRYYYLPWYDTKPMVAITSFWEDVGHRMACMNVMQFIHMRLEEDVDA
LKPSVFGND------SLWR-R

PF08165 // ENSGT00550000074414_4_Domain_4 (742, 788)

LEELSERARRPLPSSGG-QVPATFLDLQLRKLRVRLLHQ
IGKAADK

ENSGT00550000074414_4_Linker_4_5 (788, 833)

TSWKNPLKKLIGKAENWLS-----------------RIAVAITET

PF08150 // ENSGT00550000074414_4_Domain_5 (833, 916)

QI--CIPD
VLIWMLCDENRVAYARVKSHSILFSKASAQARGRLCGKTQTVFMQGPRT---------KE
KPNAIPAVLRVRMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1294)

GQMTDSAEFMKCCEGHILVYAET---YENQKKTHGIWGTRDLLPH
PSFSDVTGQISLPRNKFKPPVGWKWDGEWAVEPQRRLLLDKETNHSELLVEVYENQSREP
RQPWTPASIPFSTASGAPSPPKEDIECPKGWNFMDEWKVELNRAVDDAGWEYGVGIPPAE
FPRTWNVAEKTYHTHRRRRWLRKRCRDLNKET----QE-NNMMSFLRLHSET---KVKPD
TWEYAPMTGWRFHLQQLPGDTFRRRCWRRRLVPVAPSHGAPIFHLEGSLDGVEVE-----
-------------------------------EEGKKKKGEAEKKEGKEVEK---------
-------QPSQSLLKMNTPLLYC-IFKSPVYFQ

PF00168 // ENSGT00550000074414_4_Domain_6 (1294, 1391)

LRCYIYQARDLVGA-----STKGSADP
VAHVSFVHTSQCTKIVHG---TLHPLWDQTLVFENILIYGDPRATEEDPPVVAVEIVDAD
PTSRSEHFMGRCLSIPKVYLDLNL---------------RRMPRLQKLRMMKE-QTEAGE
LLAAFELLLDKKDGS---------------LGKHP---PPAWKDGLYTIPKEIHPILRLM
ALE---------------------------------------------------------
---------ILAWGLRDIKNYNLLAINNPSLIVECGMESLHTPIIKNFQENPNFPINIYL
M------KVYLPVDEDYAPPIELKVIDHREFGYKPVVGHASVQPLRQYYCDPWAEKKAHN
LPPRALWEASLMSPGFTTPKLESVIIQI------------NLL----NDLLASKYMADEE
--DEEVDWWSKFY--VTTGDLA---KSGNYLKLGFDTVKIYNCELEEVPEFHGFQDFCQT
FKLYREAVTVEDPIIGGEFKGLFRIYPIPEDPNIPPPPRQFQELPQ--NICQMCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYI
IRALNLQPKDRNGLCDPYVWIKIGKKIVGERNDYI--PNTLEPLFGRMYELMCCIPLEKD
LKVCLFDFDVFPPDDSIGE

ENSGT00550000074414_4_Linker_8_9 (1940, 2116)

TTIDLENRLLSRFGANCGLPQTFCVTEKKPFSAYTRVRVLL
ILENIWADALYPAPGVLTSASSEERYRGLALSQALGKTQQPLHDYLGPAKERLALYLLRT
CGLVPEHIETRTLYSTAHPGIDQGKVQMWVDIFPESLGEPGPPFDIVPRKPH--------
-KYELRVIIWNTKDV

PF00168 // ENSGT00550000074414_4_Domain_9 (2116, 2175)

DLEDTNIFGDRMSDIYV-KGWLDGLEEDKQKTDVHYRSLSGEGNF
NWRFVFPMDYLPMEQVLILNKKVGAG----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------TALEAARQKLMVPGY-AAHKELFAKPQHFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 298)

VQVKVFEARQLMGNNLKPLVKVVI
GGHQYHTRTKMGNNPFFNEIFFQNFHE-IPAKFFDYTILIQVLNSSVVRAHSEIGRF

ENSGT00550000074414_4_Linker_1_2 (298, 299)

Q

PF08151 // ENSGT00550000074414_4_Domain_2 (299, 373)

TD
IGFIYHSQGHALQRRWLGLCQPNEPNSGVRGYLKV-TICALGVGDQALVDQKL---PYDA
EDTKIHIFKSAM

ENSGT00550000074414_4_Linker_2_3 (373, 381)

VPV-NLAY

PF00168 // ENSGT00550000074414_4_Domain_3 (381, 482)

LQFFIYCAEDLHLSESQ--GGREEKSFNFLFTEKHHLVSP
MLEVELIGEKLKTLVKT-QTENPIWNEILTLQIQLPCLSSYIKFRVWDCPKGKLWSEIGT
VSLVLNQISSTGAEIEGKCLSH---------LAALSPSLLAGMYSGFLPCFGPSFLTLHG
GFRAGTVF-P-GLSSSIPSSV-KDGLEYRGRVFL-ELVTNIKSHPDSR-IKDL---SQEV
TSV---EKHKNRLKYGLCIIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDRNYKPLVSTTQ
---YSPVIYDG--NIYNYVPWYNTKPVVALTSYWEDISFRTDCLNLLHFTRDRLKANLDT
LKSM-RNPRD-PALLPQWRKLLRDLVEDCKRPLPCMTH-QPKATELDGKRWQLRNLLLKE
LAQKAKEV----QPRDMVATVEGWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 918)

PQV--SIPD
VVIWLMAKEQRVAYAQVPAHSVLFSPTGPLHCGKFCGKTQTLLLQHPEG---------EG
RKDSLPAHLRVCMWLGN

ENSGT00550000074414_4_Linker_5_6 (918, 1294)

VTDSWDLQLLREGQVVVYAET---YENQAKYKDQWGQQGLYQC
PNFSDVLGHKALPKEDFKEPLGWHWEGKWTVEPQRRLLLDTDINKSQVLEEVYENQQRDL
AGAWVPAATPNTDVNGQPVEARENVKCPQGWHVKKNWTVELNHAVDNEGWEYGVGIQPSG
LPQVWNSVEKTYYSCRRRRWARVRCRNHGK----LNLE-QETLSFLQLDHPG--PTQEEE
GWEYGTM-GSKFHLNPQPQSRFRRRCWHRRLAPNKDKGIAPIFLLEGSLGKD--------
--------------------------------QKR---QEENRPPSRGLSRTLRGSWKPA
--------PEDTLPPPHLPFIYC-VFNKPHYYQ

PF00168 // ENSGT00550000074414_4_Domain_6 (1294, 1393)

LFCYIYQARNLMGN-----QIQTFQEP
FVRLVFLNHSQCTQTLRS---SAAPTWAQTLIFQHLLLYESPHDTRESPPLVVLELWQRD
SRG-KESFRGRSMWPPVVWLDVQH---------------RVLPPMRWHPFAKELGEEEGE
ILASCELILETESLR-----------------RKLPILSVPWKNGVFTLPKSMQPTLRKM
AVE---------------------------------------------------------
---------VLAWGLRNMNQ-----VRSPQLLVECWEEARQTEPIRDFQTNPNFAQSVLF
L------TLYMPTEEAYALPLVLKVVDNKDFGQQTLVGQANIDSLQPYFCDPWASD----
---------------YVPPRLPKNR-NWAHPPPCPSPT-SDDLRM--KDLCASSKAEDED
E--YEVDWWSKLF--WATGDG----KSLKYKDKDYHTLEVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKSDSPVV-GEFKGLFRVYPFPENPGAPQPPRQFLVWPHKEDFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTKLGNRDMYQ--PNTLNPIFGTMFELSCTIPLEKD
LEIELYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSQSYCLSGP--FRWRDQVPPSF
LLEHHAKRKG-LLPPLFNPDGDSVFYNGKKFKLQRFEPQPPTARYLGPKKERLALYLLHA
QGLVPEHLETRMLYSSSQPGIDQGKIQMWVDIFPKKLGPPGPPVNIRPRQPT--------
-RYELRCIIWKTAHVDLKSVNLSNEKMSDIYV-KGWLFGLEKDMQKTDIHYQSLTGEGIF
NWRFIFTLDYLVAEQMCVLSEKNYIWSLDPLVMKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2221)

ARLIIQIWDNDIFTTDDFLG--VL
ELDLSDMPFPAQHPSLCSIRMMDADPKWPHLLQNKRFSLFKKKTATGWWPCQVLE-DGKW
RLSGKVKMTLEILSEEDALIRAAGRGQSEPNQYPTLHPPPRTNTLLSWFQSPIRNFCYVF
WKRYRFKIIIMSIILIIGLMLFSFMYSAPGYLAMSWIKPEL-------------------
-------------------------------------------------------

------------------------------------------------------------
-----------------------------------FVGMATVLLRPLVDQPSKTLLVKDL
PLLTHSMEPTTXXXXXXXXX------------------------------XXXXXXXXXX
EDPLGTAAQEVEMQKLMIPGY-TVPRALSSKAQDFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 260)

VRVRVFEARQLLGNNLRPLVKVTI
GGKEHRTRIKLGNNPFFNEVSW--------------------------------------
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-----------MIPCGM-----------------RFIGLATVLLKPLLKQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSNQ--------------DIEKTGA
EDLLGIMAREAARQKLMVPGS-TAHRALSSKPQHFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 296)

VRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILIQVVNSSAMRYKAEIG

ENSGT00550000074414_4_Linker_1_2 (296, 300)

RFQT

PF08151 // ENSGT00550000074414_4_Domain_2 (300, 360)

D
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKL---LYG

ENSGT00550000074414_4_Linker_2_3 (360, 382)

A
EDTDIQIFKSVVVPI-NMAYL

PF00168 // ENSGT00550000074414_4_Domain_3 (382, 469)

QFFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRVLDW-----------
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-----------------MKK----

PF00168 // ENSGT00550000074414_4_Domain_7 (1585, 1660)

-ASSPQLLVEFGEESLRTEPIKDFQTNPNFPESESV
LVL----T-LMPTEEAYALPLVVKVVDNWAFGQQTVTGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ANIDFLQPYFCDPWAQD----
---------------YMHPKLPT--LSEKKNK-----DFPGYLYR--KFWFKSSKAEDDY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FRLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQ--PNTLDPIFGMMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK--------
-RYELRCIIWKTANVDLVDDNLSRQKTSDIYI-KGWLYGLEKDMQKTDIHYYSLTGEADF
NWRFIFTMDYLAAERMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2220)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPLPARHAKQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
RLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLRSPVQNFCYIF
WKRYRFKLIAFMVISIMALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIINSLNTS
NASSSILPTQD----------PNLKPTIDHELKLHPGPTNHLSDIFPELPAPGD-

MLRLV

PF00168 // ENSGT00550000074414_4_Domain_0 (6, 106)

VQSAKIDPPLAPLPRPCVSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDTGSQKEES-----------------FIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSKVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHR--------------DIEKTGA
EDLLGITAREAARQKLLVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKQ---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 494)

YLQFFIYCAEDLHLSESL---------------ENQQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRVLDCHRKDCSDEIGS
ASLSLNQISSTGE

ENSGT00550000074414_4_Linker_3_4 (494, 737)

EIEG-------------------------AYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGA---------------------------------------------
-------KHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNIKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLC

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIQTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDI
RGAWGPAAIPNTDVNGQPTEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLQL-GPA--DG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLMKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLATWDGDGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVMGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPS--------------TFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLAKSYCQSGP--FRWRDQMPPSY
LLERHAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAECVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFMWLRSPAQHFCSVF
WKRYRFKLIAFMVVSILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSNIFPELPAPED-

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDMGSRKKE-----------------SFIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHQ--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TTHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 267)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKLFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPSSGVTGYLKV-TICALGVGDQALIDQKL---LYGA
HDTDIEIFKSAVVPT-NMAYLQFFIYCAEDLHLSESP---------------GAGEGAAQ
RVPTR-------------WHPGSSWSFLIPFDT-------KLRFGVGDRVRLECPETCPV
---------------EA-------------------------PWTPFQTGLT--------
------------------------PLAYDD--------------QMQT-QGSL---SPPT
PCH---CKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDI
LKST-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 786)

HQWEKLLRELVEDCKRPLPCMTD-EPKATSLDRKRWQLRSLLLQE
LTQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSILFSRAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYVET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDT
RGAWGPAAIPNTDANGQPMEARENMKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGA----LSRE-QETVSFLQL-GPA--EG-EEE
GWEYDAF-GSRFHLHPQPRSRFRRRCWRRRLAPDEDKGVAPVFLLEGSL-----------
--------------------------AMDLKYRAG--KEEDSKPWPWGLDR-Q--FWDPQ
--------RQDA-WPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----HILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKELPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLAMWDGGGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPR--LSEKKHQ-----DFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-EEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPEDPEAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRATNLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPVFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPDEDAVFYNGKKFKLQSFEPQTPAVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERTCVQSQKEYIWS

PF00168 // ENSGT00550000074414_4_Domain_9 (2188, 2230)

LDATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2295)

PARHAKQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
RLDLAKSLFLSRSR

PF16165 // ENSGT00550000074414_4_Domain_10 (2295, 2372)

EEEALIKPAGRGQSEPNQYPTLHPPLRPHTSFMWLRSPVQHFCSVF
WKRYRFKLIAFVVISITALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSNIFPELPAPED-

MLQLIVESAKVQPPQTP

PF00168 // ENSGT00550000074414_4_Domain_0 (18, 62)

PPSFCVTVYFRDVKKKTRVIEDNNPIWNET-LVWHLGPQLLEI
D

ENSGT00550000074414_4_Linker_0_1 (62, 218)

SYLQVILRDISQKKSE---------------SPRTFGVSTVFLRPLAENPHEPLDLTEL
PLVSHTTYPTKSTITLQITYLPQM-----------------------------AQPKSET
WQSLGIGCKEAEGQEIMVTGH-NVRMPLTFKPQDFQV

PF00168 // ENSGT00550000074414_4_Domain_1 (218, 264)

QVRIFEARQLHGNNIEPVVKILI
GKHEHRTRIKKGNNPFFNEKFFH

ENSGT00550000074414_4_Linker_1_2 (264, 299)

NFHHRYPTDFFEEILSIR-----------------

PF08151 // ENSGT00550000074414_4_Domain_2 (299, 368)

ID
IWIIYQSPGHTLMRKWLGLCHSNKPYLGIRGYLKV-TVSVLGAGDEAPVDHGH---LHET
GEMEKNL

ENSGT00550000074414_4_Linker_2_3 (368, 384)

FMSAIVPI-QLATFCF

PF00168 // ENSGT00550000074414_4_Domain_3 (384, 481)

YIYSAEDLHFSK-----------------EKKSSMNP
LLEVEIAGKILKTNPKL-QTERPRWDETLTFSVQLPCMTNHIKLRVLDWDKKKHNEVIGT

ENSGT00550000074414_4_Linker_3_4 (481, 732)

ASLNITHLCSTGALTKVNSMT-------------LPLPLFSGEFSGFLPCFGPSYLILHG
GEKALSWNFPDEEPFPL-DS-TEEGLIYQGRVLM-ELVCGIQVSFPFPCLPDLGCGSDVC
FIK---QNELNQQNYGLCIIFLSSTMMPAFKSQIHFEVTLG-HYGSKMDQNYKPLASTTQ
---YSQAVIDD--TSYHHLPWHNSKPVVTLTSTWEDVSYRMDSLNVLHMARDRLKSNLEA
LKSF-QNPKN-

PF08165 // ENSGT00550000074414_4_Domain_4 (732, 787)

PALSRVWKKLLEELMEDCKRPLPQISD-QPYSTILDQNLWKLRKLVLQE
LADEAM

ENSGT00550000074414_4_Linker_4_5 (787, 832)

NSK--HKDTEMLPAAENWLY-----------------RLNSVILE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQS--GIPD
IVIWLLCKEHRVAYTRVPIHTILFSQAGPFYGGKFCGKAQTLFMK-------RYFFGAQE
QKGIMAAQLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GSVLNSSDLAKIGYNDFIFYSKT---YENQAMFQGKWGPEGLKNY
PNFSDASGNYILPKENFQVPPGWEWQGSWFVEPQTTFFVDTDINQNQILEEVYENQTRDI
WGSWAPAAIPNTDMIGQPVQAREDMECPEGWSIKKNWNVELNDAVDNEGWEYGVGNPPSD
IPKAWTAVEKTYHSWRRRRWVRQRFQHPGVHKDEQKE------------SPD--LHGEDA
GWEYDSF-GFKFDPNPNPDSVLRRRCWHRRMVPTEDVSMSPIFFLEESLAKDSRYQVPSC
SIPFLCYSSSSKQSTNHRVG--------------NRPQKDSEYPMPI---LAPKSPWRTY
ILGLSFEPDSRQVGNPSTPFISC-IIYKPQYYQLF

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1356)

CYIYQVRNLISN-----HIQTFSDS
FIQVIFLHYGQRTRTLET---SLVPTWSETLIFDHILLDEKPQDIEENPPPMCLELWQLN
SQG-KKSLWGRSICSPVVYLDLQK---------------RVLPPLNWHSISKETGEEEGE
ILASFELILETEIP----------------DNQKSPLMSIPWKNGYFTLPQNIQPSLKKT
AIE---------------------------------------------------------
---------ILAWGLRNIHK-----AYSPWLVVECGEETLNTAQIKDYHSNPNFPQAALL
L------TVFLPQEEAYTPPLVLKVVDQQNFGIQMVIGQAIVYCLRPYFCDPWAED----
---------------YVPPRLPGIWKNTIKKK-----KKKKFFDHKNRKHFKSIHTEEEH
M--HEVDWWSKMF--WATGENS---KMWDY--KDYYALKIYDCELEAVSDFQGLQDFCQT
FNLYSGQKTKDSPIV-GEFKGLFRVYPLPENPKQANPPRQFQNLPEKESCPQQCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1939)

RVYI
IRALGLQPKDNNGLCDPYVILKLGKTVLGSRHHYK--PNTVDPVFGMMFEMNCTIPLEKD
LEITLFDFDLISPDDKIGSTFIDLEDRLLSTFGARCGLPKSYCLSGP--FQWRDQLTPSH
LLEQYAHRKG-LPPPDFSDE-DCIIFSGRLFRLQNFEQQTPPIKHLGSPKERLALYLLQA
QGQVPEHVETRTLYSNTQPGIDQGKLQLWVDIFPLHLGPPGPAVNISLRKAKSRASEYSD
HRYELRCIIWETRNVDLQDVNITGERMSDIYI-KGWMHDMEEDMQKTDIHYRSLTGSASF
NWRFIFTFNYLPTEQVCVLSKK

PF00168 // ENSGT00550000074414_4_Domain_9 (2183, 2216)

EFIWSLDPTVEKIPPRLLIQVWDNDKFLPDDFLG--IL
ELDLCEMPTPARSSHECTLNMIENKPKWPFKFLHKHVSLFRQKTLTGWWPCQVLD-NNKW
RLSGKVKMTLEVLTKKEADERPAGRGRSDPNQYPTLHTPIRPETSFLWFLSPWLSFQHIC
WNRYRWKFTLSILIMSVLLLVLVFIYSTPNYLAMKLIKPEFQLTRPL-------------
-------------------------------------------------------

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-----------------------MTLG-----RGR--PL-CLL----PEGQNDLPCQDEY
E--HEVDWWNKLF--WATGDA----KSLQYKHKDYHTLKVYDCELEAVPAFEGLQDFCQT
FKLYQEEPKLDSPVV-GEFKGLFRVYPFPEDPEAPKPPRQFTVWREKEDFPQECL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYI
VRAINLQPQDANGLCDPYVILKLGQTKIGNRHKYQ--PNTVDPIFGMMFELSCTIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMHPSF
LLERHAKQKG-LPPPLFNPEEDSVFYNGKQFRLQSFEPKPPTVRYLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIKPRKPK--------
-RYELRCIIWKTAQMDLGKSL--SGEISDIYV-KGWLFGLEKDMQKTDIHYYSLTGKSDF
NWRFIFTMDYLAAEHMCVQSQKDYI

PF00168 // ENSGT00550000074414_4_Domain_9 (2186, 2228)

WSLDPTVMKFPARLIIQIWDNDIFSADDFLG--VL
ELDLSDM

ENSGT00550000074414_4_Linker_9_10 (2228, 2282)

PLPARHANMCSIRMMDTDSKWPYFLQYKHVSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEILSEKEALIKPAGRGHSEPNQYPTLHPPLRPNTSFL-FRIPVTTLCHVF
WKRYHFKIIAAAIIFIIALLLFNFIYSAPHYLAMNWIKPGLRLSAPLKIYSNVINPPNTR
IANPSVLTGQH----------LNLNPAADHELKFLQGPMNHLQDIFPELPALQD-

MLQLVVDSATINPPLSPP

PF00168 // ENSGT00550000074414_4_Domain_0 (19, 100)

PRPCVTAYFRDIKRRTHEAEGNNPIWNET-LIWYLWDCPLQN
DSFLQIILRDVGAAKKD-----------------RFIGL

ENSGT00550000074414_4_Linker_0_1 (100, 217)

ATILLQPLVKKPSEVLSLKDL
NLLNHLMQSTDCTVTLHVTL---------------ARKQYA--------------SKLGD
-DLLGPSAQEVARRKLMVPGS-GMPMALSSKPQHFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 296)

VRVKVFEARQLMGNNIKPMVNVVI
GGYQYNTRIKMGNNPFFNEIFFQNFYE-VPAKLFDETILIQVMNSTLMRFNSEIG

ENSGT00550000074414_4_Linker_1_2 (296, 300)

RFQT

PF08151 // ENSGT00550000074414_4_Domain_2 (300, 352)

D
IGFIYYSPGHTLMRKWLGLCQPNEPNSGVRGYLKV-TICVLGVGDQVLVDQ

ENSGT00550000074414_4_Linker_2_3 (352, 382)

EM---PYGA
DDTTTEIFKSTVVPT-NVAYL

PF00168 // ENSGT00550000074414_4_Domain_3 (382, 481)

QFFIYCAEDLHLK-------------------KQHLASP
VLEVELIGEKLKTNVLT-ETENPIWNQILTFQIQLPCLSSYIRFRVLDCPKNSCQDEIGT

ENSGT00550000074414_4_Linker_3_4 (481, 738)

VSLFLNQISSTGAEIEG-------------------------MYSGFLPCFGPSFLTLRG
GKKAPFRI-Q-EENTNIPDSL-KDGLTYRGRIFL-ELSTHVTSHQDLK-RKDL---SSEV
ISI---ERHRHRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPCVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVISQWEDISFRMNCLNLLHFTRDRLKANLDT
LKSI-KNPRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 787)

WEKLLRELVEDCKHPLPCMAH-QPRATELDKKRWQLRSRLLQE
LSQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EV----KPRNMVATVEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--SLPD
VMIWLMSKEQRVAYAQVPTHSILFSPTGALHSGRFCGKTQTLVLQYPEG---------EG
Q-DMLPAHLRVCMWF

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GNISDSKNLQLLREGEVVVYAET---YENQAKYKDQWGQQGLYHC
PNFSDVMGHKALPKEDFQAPQGWHWQGQWRVEPQRRLLLDVDINKSQVLEEVYENQCRDT
TGAWVPAAIPNTDMNGEPVEARENVQCPRGWHVKESWIVELNHAVDSEGWEYGVAIEPSG
QPRVWNSVEKTYYSCRRRRWVRVRCRNHGK----LSLE-EETLSFLQLHHPI--PAKDED
GWEYGTF-GSKFHLNPQPQSQFRRRCWHRRMVPNKDKGIAPIFRLEGSLDMD--------
-----------------------------LKEKGR----KEEMRLTQAPDKTIRSSWRPA
--------QEDI-QLHALPFIYC-IFNKPHYYQLF

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1354)

CYIYQARNLMSN-----QIQTFQVP
FIRLVFLNHSQCTQTLKS---SAAPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1577)

QHLLLYENPEDTKASPPLVVLELWQQN
AQG-KESLWARSMWSPVVWLDVQK---------------RTLPPLRWHPLVKLLGEKEGE
ILVSCELILETESVK-----------------ERPPILSVPWKNGVYTLPKSIQPTLKKM
AVE---------------------------------------------------------
---------ILVWGLR

PF00168 // ENSGT00550000074414_4_Domain_7 (1577, 1660)

NMKQ-----VHSPQLLVECWEESLQTEPIKDFQTNPNFKQSVLF
L------TLFIPTEEAYAPPLTLKVVDNQDFGQQTVVGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ANIHSLQPYFCNPWAED----
---------------YVPPQLPMLSVN-----KYQ--KLLDYFYE--KFWISPSKAQDQY
Q--HEVDWWSKLF--WATGDA----KALQYKYKDYHTLKVYDCELEAVPAFEGLQDFCQT
FRLYQEEPKLDSPVV-GEFKGLFRVYPFPEDPKAPKPPRQFLVWRNKEDFPQECLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYV
VRAINLQPQDSNGLCDPYVILKLGQTTMGNRDKYC--PNTLNPIFGIMFELSCTIPLEKD
LEIQLYDFDLFSSDEKIGTTIIDLENRLLSGFGARCGLSKSYCYAGP--FRWRDQMTPSF
LLERHAKQKG-LPPPLFSPEEDTVFYNGKKFKLQSFEPKPPPVHYLGPKKERLALYLLHT
QGLVPEHVETRTLYSNSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIRPRKPK--------
-RYELRCIVWKTAQVDLRRSL--TTGMSDIYV-KGWLAGLEKDMQKTDIHYYSLTGESNF
NWRFIFTMDYLAAERVCVESQKDYIWSLDPTVMK

PF00168 // ENSGT00550000074414_4_Domain_9 (2195, 2220)

FPARLIIQIWDNNIFSTDDFLG--VL
ELDLFNMPLPTRHANLCSIRMMETNSKWPYFLQYKHFSLFKKKTITGWWPAQVLD-GGTW
HMSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPNTLFI-LRSPVTILCRVF
WKRYHFKIIIGAIIFIIALMLFNFIYSAPNYLAMSWVKPELRLNAPIKTPTNIMNPPSSS
NAHSSILTSQH----------QNLNSTTDHELKLLQGPMNRLQDIFPELPAPQD-

MLR

PF00168 // ENSGT00550000074414_4_Domain_0 (4, 110)

LVVESAKINPPLSPPPKLCVTVYFRDVKKKTRIQEGNDPIWNET-LIWYLWNQPLEI
DSFLQVTLQDEGSRKKE-----------------RFIGTATVLLKKLVQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

KPDEVLDMKNL
VLLNHSMKPTDCTVNLQLAQ---------------MHDQ--------------HTEMMGH
EELLYSTANKVTQQKLMVPGY-TMHRTLTSKPQQF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 301)

QVRIKVFEARQLLGNNIKPVVKINI
AGHQHITRIKIGNNPFFNEIFFQNFHE-VPAKFFEENILIQVVDSAASRSKAEIGRFQTD
IGFIYHAPGHTLLRKWLGLCQKNKTNSGVRGYLKV-TICALGVGDMALVDQKL---PYET
-GTQVKIFKSAAAPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHFRK-------------------HQSASP
ALEVELIGNKLRTHPQS-QSDSPIWNQILTFQIQLPCLSSYIKFRVVDCSKRDCWEVIGS
ASLCLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 734)

GEEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKAPFRI-P-EDGTCIFDAV-KDGLTYQGRIFV-EIITRMKSQQDSV-IKDL---SREV
TQI---ERQQYRHKYGLCVVFLSCTMMPKFKDLIQFEVSMG-HYGNKMDPNYKPLVSTTQ
---YSPVIYDG--CLYHYVPWYDMKPVVAVTSKWEDVNFRINCLNLLHVTRDHLKANLDT
LKSI-QNPKD-PA

PF08165 // ENSGT00550000074414_4_Domain_4 (734, 787)

LFQQWEKLLKDLIQDCLHPLPCMTD-QPKANNLDKKKWQLRNRLLKQ
LAQNAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

DA----KPKNMVVTAEDWLH-----------------RLNSVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQD--SLPD
VMIWLMSKQQRVAYARVPAHTVLFSPEGPLSSGKFCGKIQNLFLQYPEG---------EG
Q-DTLPAYLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVIHSKDLKLLEHGKMVVYAET---YENQAKVKGQWGQQGLYRC
PNFSDVLGRKAVPKTDFKTPLGWHWKGDWIVEPQRRLLLDTDINKSQVLEEVYENQTRNA
KGIWVPAAVPNTDVNGQPVEAMENVKCPQGWHFKKSWIVDHNYAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSSRRRRWVRVRFRDHQE----LSQE-QETLSFLQTQDIS--EE-GKE
GWEYGTF-DSKFHLDPKPTSRFRRRCWHRRLAPNKERGVAPIFFLEGSLAAELE------
-------------------------------NQ-S--KPEPHRTRS------WWDSWRRM
--------QEDP-WIPNMPFIYYFSLPEPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1382)

QLFCYIYRARNLMYN-----QILTFQEP
FIRVVFLNHSLCTQTLHS---SAAPTWAQTLIFQHLLLFENPKDTKENPPFVVLELWQHD
SKG-KKVLWGRSMWPPVVWLNLQS---------------WTLTPLRWHPIMKELGEEEGE
ILASCELIL--E-----------------K-DVHLPMLSVPFKDGIYSLPKNIQPTVKMM
AIE---------------------------------------------------------
---------ILAWGLRNMKK-----VRYPQLRVECGEQSLRTDPISNYQQNPNFPIKNFL
L------TVLMPMEETYALPLMVKVVDNQVYGQEIVVGHANIDFLQPYFCDPWALN----
---------------YTPVNIPP--LPEKKPD-----TFLDFLYK--KFWFDSRKD----
--EYDVDWWSKFF--WATDNDD---KSLKYKYKNYHTLKVYDCELEAVPDFQGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPEAPNPPRQFSSWPETDNFPQTCM

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKFGSRDSYY--PNTLNPIFGTMYELKCNIPLEKD
LEIQLYDFDLVTSDDEIGMTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2122)

LLSGFGARCGLSNCYCKSGP--FRWRDQLSPSY
LLDRYAKQKG-LPPPVYDLEKDSVFYNGKMVQLKSFESTPPTLKDLGPKKERLALYILNS
QGLVPEHVETRTLFSNSQPGIDQGKIQMWVDVFPFVLGPPGRPVNISPRKPK--------
-RYELRCIIWSTTQVDLVQQT

PF00168 // ENSGT00550000074414_4_Domain_9 (2122, 2233)

FSRDKTSDIYV-KGWLFGQEKDMQKTDVHYHSLTGDAVF
NWRFIFTIDYLVTERVCVQSQKDYIWSLDPVSMKFPARLIIQIWDNDLFSPDDFLG--VL
ELDLSDMPLPAV

ENSGT00550000074414_4_Linker_9_10 (2233, 2280)

SSKQCSLKMMEPDPKWPH-TQQKRISLFKKTNVTGWWPCQVLD-GDK

PF16165 // ENSGT00550000074414_4_Domain_10 (2280, 2372)

W
RLSGKVKMTLEILTEKEALIRPAGRGQSEPNEFPKLHPPVRHDSPFMWIRSPIKNFCYVF
CKRYRYKIICLLMTLLLAMILFNFIYSAPNYLAMAWIKPELRLNPPIKIV-NLISSANTS
NINSSVYREEG----------H----------------RNHVKDVVPGIPAP---

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTSVVEGNEPVWNET-LIWHLWNRPLEN
DSFLQVMLQDMGSQKKE-----------------RFIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLLIQPSEVLLVKDL
TLLNHSMKPTDCTVTLQVDY---------------ISNQ--------------DIEKTGA
EDFLGITARETARQKLMVPGS-TVHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 266)

QVRVKVFEARQLMGNNIKPVVRVSI
GGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAEFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPSSGVRGYLKV-TICALGVGDQALVDQKL---LYGA
DDTDIQIFQSAAVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGKKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRILDCHRKDCPDEIGT
ASLFLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITEIKFHQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIHDG--NSYHYVPWYDTKPVVAVTSNWEDISFRMNCLNLLHFTRDRLKVNLDT
LKSI-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 787)

HQWAKLLRELAEDCKHPLPCMTD-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPRDMVATVEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSILFSPAGPLHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAEM---YENQAKHKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVDPQRRFLLDIDINKSQVLEEVYENEVRDA
RGTWGPATIPNTDVNGQPMEARENVKCPPGWHFKKDWAVELNHAVDSKGWEYGMEIPSSG
QRQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QETLSFLKL-GLA--KG-EEE
GWEYGTF-GSTFHLNPQPQSKFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDVKY-AG--KEEDSKTWPLRLDR-Q--FRDPL
--------RQDT-RPPNIPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1390)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQHD
SWG-KESLW

ENSGT00550000074414_4_Linker_6_7 (1390, 1572)

GRSMWPPVVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILETEKL---------------R-EKQLPILSVPWKNGAYTLPKNIQPTIKRM
AIEVLAMWDGNGG----G---LECNAALLVLPDYGIQSSH-PKKDYL-GGGRRQ--E---
-----RNEEIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPHLLVEFGEESLKTEPIRDFQTNPNFPES--V
LVL----RVLMPTEEAYALPLVVKVVDNWAFGQQIVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1900)

LQPYFCNPWAQG----
---------------YMHPKLPT--LSEKQHQ-----DFLGYLYE--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSPKYEYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEALKPPLQFLVWPEREDFPQLCLVRVYV
VRAINLQPQDYNGLTPVR----E-----GGTETWPTASA

PF00168 // ENSGT00550000074414_4_Domain_8 (1900, 1948)

VSNTLIPRMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSH
LLERYAKRKG-LPPPLFNPEEDAVFYNGKKFKLQSFEPQTPTLHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIKPRKPK--------
-RYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYYSLTGEANF
NWRFIFTMDYLATERMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDTFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDANPKWPYSLRYEHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2373)

LSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLHTNTSFMWLQSPVQHFCYIL
WKRYRFKFIAFMVISIIALMLFNFIYSAPHYLAMNLIKPHLQLYPPIKIF-NIITSINTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPRNHLSDIFPELPAPQD-

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 109)

LQLVVESAQIVPSISPTPKPCVIVSFRDVKKRTQMAEGNNPIWNET-LIWHLWNRPLEN
DSFLQVILQDMGSMKKE-----------------RFIGLATVLLKPLM

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KQPNRILFLKNL
VLLNHSMEPTNCTLNLKVAY---------------ISPQ--------------HIEKTGN
KDPLGTTAKKATQQKWMVPGT-VMHRALSSRPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLMGNNIKPVVKVTI
AGHQFNTRIKMGNNPFFNEIFFQNFYE-VPAKVFDEIISIQVLNSSAKRYEAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQPNKPGSGVQGYLKV-TICALGVGDQALVDQKL---PYMA
-ATEVEIFKSTAVPI-NLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLRHN------------------SKSANP
VLEVELIGEKLRTRTWT-KSDKPIWNQILTFQIQLPCLSSYIKFRLLDCSRKDCQEEIGT
ASLFLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------LYSGFLPCFGPSFLVFHG
GKKAPFRI-Q-EEGTCIPDTV-KDGLAYRGRVFL-ELTTQVTSHQDTT-IKDL---SQEV
VRI---EKQQSRQKYGLCVVFLSCTTMPNFKSLIQFEVSMG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDG--NKYHYVPWYNTKPVVAVTSFWEDVTFRMNYINCLHVTRDRLKANLAI
LKSI-RNPKD-PALLR

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLRKELVEDCRYPLPSMID-HPKATILDKNKWKVRSLLLKE
LEQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRNMVATAEHWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--SLPD
VTIWLMANEQRVAFAQVPAHTILFSRAGPLCSGRFCGKIQNLLLQYPEG---------EE
QQNVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLKLLHQGNLVVYAET---YENQAKYKDQWGQKGLDRC
PGFSDVMGHKALSKTNFIEPTGWHWQGNWIVEPQRRLLLDIDINKSQVLEEVYENQIRDA
TGTWIPAAIPNTDLNGQPVKALVDIECPQGWHFEKSWAVEHNLAVDNEGWEYGVGIPPSG
LPQVWNSVEKTYYTCRRRRWVRLRFRNHEE----QGNE-QQTLSFLQLQDLA--KE-GEE
GWEYGTF-GSKFHLDPQPHSRFRRRCWHRRLAPNKDRDIASIFLLEGTLVKPL-------
----W--R------------------TMHEQY------------------K-VTESQKPI
--------QEDS-YLSSLPFIYH-TLNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1381)

QLFCYIYQARNLRSN-----HILTFQGT
FIRVSFLNHSLCTQTLKS---SVAPTWAQTIIFQHLLLYENPKDTKESPPLVVLELWQHD
SKG-KEILCGWSMWPPVVWLDIED---------------RTLPPLRWHPVLKGFEEEEYE
ILSSCEMILETEKL---------------K-QKHMPILSIPWKDKIYTLPKNIQPTLKKM
AIE---------------------------------------------------------
---------VLALGLRNMKE-----VRYPQLLVEFGEQSVGTKAIQDFETNPNFPDSVLF
L------TVFMPTEETYALPLVVKVVDTQQYGQQITVGQANVDFLQPYFCDPWNLD----
---------------YIPPKLPGMSLSAD--------PFLG---R--GFQPDPLPCQDEY
E--HEVDWWSKLF--WATEDDH---KSLTYKHKDYHTLKVYDCELEAVPAFQGLQDFCQT
FRLYQEQPKADSPVV-GEFKGLFCIYPFPENPAEPKPPRQFMTWSETEDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
IRGINLQPQDFNGLCDPYVTLQLGQTKLGNRDSYQ--PNTLDPIFGMMFELTCNIPLEKD
LQIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCHSGP--FRWRDQMLPSY
LLERYAKRKG-LPPPMFDPKDDSVFYNGKIFNLKNFEPKPPDVYGLGPKKERLALYILHT
QGLVPEHVETRTLYSDSQPGIDQGKVQLWVDIFPKKLGPPGPPVNISPRKPK--------
-RYELRCIIWQTNHVDLVHETLSRDKMSDIYV-KGWLFGIEKDMQKTDVHYHSMTGEGNF
NWRFIFTMDYLAAECMCVQSQKD

PF00168 // ENSGT00550000074414_4_Domain_9 (2184, 2228)

YIWSLDPTSMKFPARLIIQIWDNDFFSSDDFIG--VL
ELDLSDM

ENSGT00550000074414_4_Linker_9_10 (2228, 2276)

PFPARTSKQCSLRMMDTNPKWPY-RQHKRFSLFKKMTVTGWWPCQVQD

PF16165 // ENSGT00550000074414_4_Domain_10 (2276, 2373)

-GNKW
RLSGKVKMSLEILTEKDALIRPAGRGQSEPNQYPTLHPPLRSDTAFMWLRSPIKNVCLAC
CKRYRFKILVAFIILVGVFVLFNFIYATPNYLAMSLIKPELRMYPPIKII-NLINSQNTS
RDSFSDLQHPNLQT------TGDQTTT--TLLQEGGNSKNYQSLIFPDFLELVAP

MLRLVVESARIKPPLSPLPRPCLTVYFRGESQL------TSPYLQQT-LIWHLWSRPLEN
DSFLQVILRDMGSKKKD-----------------RFIGLATVLLKPLVKKPREVLFVKDL
ILLNHSMMPTDVSQALKA------------------------------------YVSPGS
GDPLGMTTREAARGKLMVPGSAGMHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 301)

QVRVKVFEARQLMGNNILPVVKVTI
AGQQYHTRIKMGNNPFFNEIFFQNFYE-VPAKFFEEIVL--VLNSSVMRSKAEIGRFQTD
IGFVYHSPAYPVLW-------------------------------SLQVDQKL---PYRA
-GTDIEVFKSTAVPM-TMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLKLFIFCAEDLN-----------------------QPVSP
VLEVELIGEKLRTNVQP-QTDNPIWNQILTFQIQLPCLSSYIKFRALDCSRSDCQAEIGT
ASLSLGHISSS

ENSGT00550000074414_4_Linker_3_4 (492, 738)

GAEIGG-------------------------LYSGFLPCFGPSFLPLHG
GPKARLRI-Q-EQGTGVPDAV-RDGLSYQGRVLL-ELVTQIKSHQHTM-IRDL---SQEV
ARI---EKHQNCQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDG--NIYHYIPWYNTKPVVAVTSSWEDVSFRMHCLNLLHFARDRLKANLDT
LKSM-RNPED-STLLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 787)

WEKLRRELIEDCRRPLPCMAD-QPKATHLDRKRWQLRSLLLQD
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPKNMVATVEGWLH-----------------CLNSVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 900)

PQM--SLPD
VMIWLMAKEQRVAFAQVPAHTILFSPAGPLHSGRFCGKIQTLLLQHPGA---------G

ENSGT00550000074414_4_Linker_5_6 (900, 1293)

L
STEPQSTHLELR--------------LRPNTPRFPLLQ---YENQAKFKDQWGQQGLYHC
PNFSDVMGHKALPKSKFKAPSGWHWQDSWRVEPQRRLLLDIDINKSQVLEEVYENQERNI
TGSWVPSAVPNTDMNGQPSEARDTVRCPQGWHFKKNWAVELNHAVDSEGWEYGVGILPSG
LPRVWTSVEKNYHSRRRRRWVRMRFRNQG----KLDSE-ERTMSFLQMQGLA---SEGEE
GWEYGRF-GSKFHLDQQPQSRFRRRCWHRRLAPNKNTGVAPIFLLEGSLVKLQGL-----
-----------------------------------SGACL-----QPRL---LQEQGRPQ
--------WEDP-RLPSMPFIYC-TLNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSN-----QVLAFQEP
FVRAVFLNYSQCTQRLPN---SMSPTWAQTLIFQHLLLHESPQDTRESPPLVVLELWQCD
ALG-KESLWGRSMWPPVVWLDPQD---------------WMLPPLKWHPLVKELGEEEGE
ILASCELILETEKL----------------REKHLPLLSVPWKDGVYTLPKSIQPVLRKT
AIE---------------------------------------------------------
---------ILAWGLRNMKQ-----ARHPQLLVEFGGETLRTEPIEEFPTNPNFPKSALL
L------MVFMPKEEAYAEPLVLKVLDNQDFGQQTVVGQASVDFLQPYFCDPWARD----
---------------YLPPQLP---------S-----MVLGFLYE--NFWFKSS--RDEY
E--HEVDWWSKLF--WATGDD----KSLQDKYQDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKMDSPVV-GEFKGLFRIYPFPENPEAPKPPRQFLAWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGSLKLGNRDMYK--PNTVDPIFGTMFELTCTIPLEKD
LKIQLYDFDLFLSDDEIGTTVIDLENRLLSGFGACCGLPKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPVFDPEGDSVFYRGKKYKLQSFESKAPTVPGLGPKKERLALYILHT
QGLVPEHVETRTLYSDSQPGIDQGKLQMWVDIFPQKLGPPGPPVKISTRKPK--------
-RYELRCVVWKTAQVDLVDEALSREKMSDIYI-KGWLFGLEKDMQKTDIHYHSLSGEATF
NWRFIFTMDYLAAEHMCIESQKDYIW

PF00168 // ENSGT00550000074414_4_Domain_9 (2187, 2234)

SLDPTSTKFPARLIIQIWDNDIFSSDDFLG--VL
ELDLSDMPSPARH

ENSGT00550000074414_4_Linker_9_10 (2234, 2277)

AKQCSLRMLDAEPKWPYFLPHKRFSLFKKKTVTGWWPCQVQD-

PF16165 // ENSGT00550000074414_4_Domain_10 (2277, 2372)

GDKW
RLSGKVKMTLEVLSEKEALARPAGQGQSEPNQYPMLHPPLRVGSSFMWLRSPVRHLCLGL
CRRYRCKILSFSVLLVIGFMLFKFIYSAPNYLAMSWIHPTLRVQPPIKIY-NLINSATAS
SAS-----------------------------PLLQVPKQHLGDIFPELLAP---

------------------------------------------------------------
-----------------------------------FIGLATVILDPLVKQRTEVLYVKDL
TLLNHSMKPTNCTVTLQVAQ---------------MTSQ--------------YIEKTWD
EDLLGITAREVARQKLMAPSP-ITQRIQCSKPQHFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 260)

VRVKVYEARQLMGNNINPVVKVII
GNQQHNTRIKMGNNPFFNEVG---------------------------------------
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----------------------------------------------T-LIWHLWNRPLEN
DSFLQVMLQDMGSQKKE-----------------RFIGLATVLLKPLLKQPSDVLFVKDL
TLLNHSMKPTDCTVTLQVAY---------------ISNQ--------------NIEKTGA
EDLLGITARETARQKLMVPGS-TGHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLMGNNIKPVVRVSI
GGQQHQTRIKMGNNPFFNEIFFENFHE-VPAKFFDETILIQVVNSSAMRYKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQPNNPSSGVRGYLKV-TICALGVGDQALVDQKL---LYGA
DDSDIQIFKSAAVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGKKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRILDCHRKDCPDEIGT
ASLFLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITEIKFHQDFR-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPSFKDLIQFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIHDG--NIYHYVPWYDIKPVVAVTSNWEDIGFRMNCLNLLHFTRDRLKVNLDT
LKSI-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 787)

HQWEKLLRELAEDCKHPLPCMTD-QPKATSLDRKRWQLRSLLLQE
LTQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPRDMVATVEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTHSKDLQLLRQGDTAVYAEM---YENQAKHKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVDPQRRLLLDIDINKSQVLEEVYENQVRDA
RGTWGPATIPNTDVNGQPMDARENVKCPQGWHFKKDWAVDLNHAVDSKGWEYGMDIPTSG
QHQVWSPVEKTYHSCRRRRWARVRFRNHGD----LSPE-QETLSFLKL-GPA--KG-EEE
GWEYGTF-GSRFHLNPQPQSKFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDVKY-AG--KEEDSKTWPSRLDR-Q--FRDPL
--------RQDT-QPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1390)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQHD
SWG-KKSLW

ENSGT00550000074414_4_Linker_6_7 (1390, 1572)

GRSMWPPVVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILETEKL---------------R-EKQLPILSIPWKNGAYTLPKNIQPTIKRM
AIE---------------------------------------------------------
---------IL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPRLLVEFGEESLKTEPIRDFQTNPNFPES--V
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAPD----
---------------YVHPKLPT--LSEKKHQ-----DFLGYLYE--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSPKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYSFPENPEAPKPPLQFLVWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTQLGNRDTYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FKWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPQTPTLHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIKPRKPK--------
-RYELRCIIWKTANVDLVDENFSKEKTSDIYI-KGWLYGLEKDMQKTDIHYYSLTGEANF
NWRFIFKMDYLATEHMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDTFTPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2279)

PARHAKQCSIRMMDANPKWPYSLRYEHVSLFKKKTVTGWWPCQVLD-GD

PF16165 // ENSGT00550000074414_4_Domain_10 (2279, 2373)

KW
RLSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNISFMWLRSPVQHFCYVF
WKRYRFKFVAFMVISIIALMLFNFIYSAPHYLAMNLIKPHLQLYPPIKIF-NIITSVNTS
NASSSILPTQD----------PNLKPTMHHEWKLHPGPRNHLSDIFPELPAPQD-

------------------------------------------------------------
------------MSLVK---------------NERTFGICTIFLRTLAENPDESLVLNEL
PLVSRTINPTKSTITLQITYLPEG-----------------------------NQ-NLET
WEKFGITCKETERPEIMLGDH-SVRRPLFSMPQDFQV

PF00168 // ENSGT00550000074414_4_Domain_1 (218, 297)

QVKIFGAHQLHGNNIAPVVKILI
GNKLYRTRIKKGINPFFNEKFFHNFHHVSPTEIFEEIIAIRVMDSRARRSKSEIGA

ENSGT00550000074414_4_Linker_1_2 (297, 299)

CQ

PF08151 // ENSGT00550000074414_4_Domain_2 (299, 359)

ID
IGTIYRSPGHTLMRKWLGLCHSSKPTLGIRGYLKV-TISVLGIGDLAPVDHGQ---LH

ENSGT00550000074414_4_Linker_2_3 (359, 388)

ET
GPTEKDLFISATVPI-RLANFEFLIYL

PF00168 // ENSGT00550000074414_4_Domain_3 (388, 481)

AEDLHLKTAV-----TSRLFSHTVREIKGIMNP
ILELEIAGQILKTKPRM-HTEKPRWEQTLKFSVQLPCMTNHIKLRVLDWNKSRHNDVIGT

ENSGT00550000074414_4_Linker_3_4 (481, 734)

ASLNITHISSIGAYS-------------------------RGTFSGFLPCFGPSYIILHG
GEKALSQSFLDEEPFPLLTS-TEEGLIYRGRVLM-ELVTGIQEMKTRF-FPS----RITS
TFI---ESGLSKKDYGLCVIFLSSTMMPAFEDLIHFEVTIG-HYGNKMDLNYKPLASTTP
---YSQAVFDG--TLYHFMPWQDNKPVVSLISTWEDIGYRMSSLNILRIAWDRLKSNLEA
LKSI-QNPKN-PA

PF08165 // ENSGT00550000074414_4_Domain_4 (734, 788)

LPRLWKKLLEELREDCKRPLPNMRKESTFVTILDKNLLKLRHKVLSE
LDYEAKK

ENSGT00550000074414_4_Linker_4_5 (788, 832)

SK--HEVMEMLPTAENWLY-----------------RLNAVLAE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQL--SIPD
VVIWLLCKEQRIAYARVPVHTILFSKAGPFSCGKFCGKAQTLFMQYSKEEMPKPFLKAEE
EKGIMAAQLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GSIFHSSALAETSYNDFIFYSET---YENQAMYKGKWGQQGLKNY
PIFSDVTAQQYLPMKNFQVPQGWRWEGNWFVEPQRRL-LGKDIHQKQILEEVYENQTRDT
WKSWTPAAIPNTDMIGQPVPAKESMECPKGWTIKENWNVELNEAVDDEGWEYGVGIPPSG
IPKAWTAVEKTYHSWRRRRWVRQRYQNTEEQRHEQKQ------------SPA--LSGEEE
GWEYVSF-DSKFGLNPQSDSKFRHRCWHRRMVPIENTNVSPIFYLEKSLEKEKLMAKE--
------------------------------------EKKEKDDPMAL---K---------
--------KTLMEQELRTPFIYC-IIHKPQYYQLL

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1387)

CYIYQARNLMSN-----HDQTFSGS
TIQVVFLHYGQRTRTLET---SLVPTWDQTLIFDHIPLYEKPQDIEENPPLVCLELWQQN
SHG-KQSLCGRSMCSPIVYLDLKN---------------RVLPLLRWHSFNKMPGEDEGE
VLAAFELILETEMV----------------SNQRSPLMSIPWKNGYYTLPQSIQPSLKKT
AIE---------------------------------------------------------
---------ILAWGLRNIKK-----AQSPRLLIECGGETLETAQIEDFYSNPNFPQSALL
L------TLFLPQEEAYAPPLVLKVVDQQYFGIQMVVGQAVVSCLRPYFCDPWAKD----
---------------YVAPRLPAIILKKN--------QVLDWY-------RNSEHDEEEY
I--HEVDWWSKML--WATGESK---KKWDY--SDYYTLKVYDCELEAVPDFQGLQDFCQT
FNLYYEKKTEDSPVV-GQFKGLFRIYPLSENPKQPSPPRQFQNLSEKQSGPQRCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1939)

RVYV
VRAFNLQPKDNNGLCDPYVILKLGKTVLGNRHDYK--PNTVDPIFGRMFELKCTIPLEKD
LKITLFDFDLISPDDKIGSTVIDLENRLLSSFGARCGLPKSYCVSGP--FQWRDQLTPSH
LLERYAHRKG-LPPPDFSTE-GSIIFNGRTFKLPNFEQHTPQLKHLGPPQERLALYLLQA
QGQVPEHVETRTLYSSTQPGIDQGKVQLWVDIFPLHLGPPGPAVNINLRKA---------
KRFELRCIIWETRDVDLQDVNLTGEKMSDIYI-KGWMHEMEKDMQKTDIHYRSLTGNGDF
NWRFIFTFKYVPTEQVCILSKK

PF00168 // ENSGT00550000074414_4_Domain_9 (2183, 2216)

EFIWSLDRTVKKTPPRLIIQVWDNDKFLPDDFLG--II
ELDLCEMPIPARKPSKCTLSMMESKPKWPFKFTYKHVSLFRQKTLAGWWPCQVLD-NGKW
RLSGKVNMTLEVLTKEEAEDKPAGKGRSEPNQYPTLHAPIRPESSFLWFLSPSLSIRYIC
WHHYRWKCAVFMIATSLFIMLLNFLFSIPYYLAMKLFTPEFRLAGTLPETVTKTKSTTTT
TPGGSSTTPGGSSTSPGGSSTLFYSPQTE---ADYQ-NSTNYMDIFF--------

MLRLVVESAKIDPPLTP

PF00168 // ENSGT00550000074414_4_Domain_0 (18, 111)

PPRSCVSINFRDIEKRTHVVEGNDPIWNET-LIWHLWNRPLEN
DSFLQVTLQDMGSKKKE-----------------RFIGLATVVLKPLVKHPSKVHFVKDL
TLLNHSMSQTDVSQAQEGP-----------------------------------LEEWGQ
------------------------------------------------------VVMCST
LG-----------VSFKEQMFFV-----------------------------LMKCNLSN
IGFVYHSPGHSLLRKWLGLCQPNKPGSGVTGYLKV-TISVLGVGDQAPVDRKL---PYRA
EDTDVQIFKSTAVPI-HMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHFKK-------------------HQSVNP
MLEVELIGEKLKTYVPT-STDNPIWNQILTFQIQMPCLSSYIKFRVLDCSRRDCQDEIGT
ASLFINQISST

ENSGT00550000074414_4_Linker_3_4 (492, 733)

GEEIGG-------------------------VSSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGSCISDSV-KDGLAYRGRVFL-EVITQIKSQQDSR-IKDL---SHEV
TMI---EKHQNRQKYGLCVIFLSCTMMPNFNDLIQFEVSIG-HYGNKLDLNYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSSWEDVSFRVNCLNLLHFTRDRLKANLDT
LKSM-RNLKD-P

PF08165 // ENSGT00550000074414_4_Domain_4 (733, 786)

ALLRQWEKLLRELVEDCKRPLPCMTD-QPTATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KHA----KPRDMVATVEGWLY-----------------HLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQI--SLPD
VMIWLMAKEQRVAYARVPAHSVLFSQAGPLYSGRFCGKIQTLLLQYPEG---------EG
QKNTLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDMVVYAETVSGYENQAKYKDQWGMQGLYRC
PNFSDVMGNKALPKTDFQPPPGWHWWDNWRVEPQRRLLLDIDINKSQVLEEVYENQDRDA
RGAWVPAAIPNTDTNGQPMEARENVKCPQGWHFKKNWAVELNRAVDNEGWEYGVGIPPSG
LPQVWNSVEKTYHSCRRRRWVRVRFRNPRE----LSLE-QETLSFLQQHELA--KG-EEE
GWEYGTF-RSKFHLNPQPHSRFRRRCWHRRLAPDKDKGVAPIFLLEGSL-----------
--------------------------AMDLKQHAK--KEEEDKSWL------G--FWRRI
--------PEDT-RPPNMPFIYC-IFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLMFN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1570)

HLLLYENPHDTKESPPLVVLELWQRD
SWG-KENLWGRSMWPPVVWLDFHN---------------RTLPPMRWHPIINELGAEEGE
ILASCELILETEVL---------------GQEKQLPILSVPWKNGIYTLPKSIQPTLKKM
AIEVLGVAGWTGGKHHPEQSG-MCWSSLLVLPDCPIQSLHPKKCYWEMEGDRREMKNREA
LPAPSLFWQ

PF00168 // ENSGT00550000074414_4_Domain_7 (1570, 1665)

ILAWGLRNMKK-----VSSPQLLVEFGEESLRTEPISDFQTNPNFPES--I
LLL----IVYMPTEEAYALPLVVKVVDVWIFGQQTVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVPPRLPT--LCVKQHQ-----DFLGYLYK--KFFFKSSTTKDQY
E--HEVDWWSKLF--WATGDDH---KSPKYKYKDYHTLKVYDCELEAVPVFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPHQFLVWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1949)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGKRDTYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFEARCGLSKSYCLSGP--FRWRDQMSPTH
LLERYAKRKG-LPPPLFNPEEDSVFYNGKNFKLTSFEPKPPTVHGLGPKMERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGLPGPPVNISPRKPK--------
-RYELRCIIWQTANVDLVDSNFSGEKTSDIYV-KGLQQSPCG------------PPVLSF
CWGFPILRE------HLSNSTCDYIWSLDPTSM

PF00168 // ENSGT00550000074414_4_Domain_9 (2194, 2229)

KFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMP

ENSGT00550000074414_4_Linker_9_10 (2229, 2282)

LPARHANQCSIRMMDADSKWPAFLQYKHFSLFKKKTVTGWWPCQVLD-DGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEMLSEKEALIKPAGRGQSEPNQYPTLHPPLRTDSSFKWFRSPVQNICRAC
WKRYHFKIIALVIIVITALLLFNFMYSAPHYLAMHWIKPELRLSPPIKIF-NIITPLNTS
NANSSILRTPD----------SNLKPTIDREFKLLQGPKNHLSDIFPELPVP---

MLRLVVQSAKID

PF00168 // ENSGT00550000074414_4_Domain_0 (13, 109)

PPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDMGSQKKE-----------------RFIGLATVLLKPLL

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSNQ--------------DIEKTGA
EDHLGITAREAASQKLMVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHHTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNKPGSGVTGYLKV-TIYALGVGDQALIDQKL---LYGT
DDTDIQIFKSAVVPM-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQLFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEGKQSLEP-------------TSYAPRVYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITQIKSYQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLY

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLRELAEDCKRPLPCMTY-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPKDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAEM---YENQAKYKDQWGQQGLYHC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDT
RGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVVELNHAVD--SWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QETLSFLQL-GLA--KG-EEE
GWEYDTF-GSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEGGS--V-R
EEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAG--KEEDSKTWPWGLDR-Q--FRDPQ
--------RQDT-RPPNLPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLVSN-----QILTFQAP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1572)

QHLLLYENPQDTKESPPLVVLELWQRD
FWG-KESLWGRSMWPPMVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIE---------------------------------------------------------
---------IL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----TVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YMHPKLPT--LSEKKHQ-----DFLGYLYR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSG
HRYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEADF
NWRFIFTMDYLAAERMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDANPKWPYFVQYKHFSLFKKKTVTGWWPCRVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLRSPVQNFCYIF
WKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIINSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD-

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 110)

LRVVVESASINPPLSTTPKAFVTVYFRDMMKRTRVEEGHDPIWNET-LIWHLWNQPLEN
DSFLKVILQDSVSKKKE-----------------RFIGLATVPLKRLAQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

RPKEVMFVRDL
ILLNHSMKPTNCTVTLHVAQ---------------IYDQ--------------DTEMTGN
EELLGSTVNEVTQKKLMVSGL-PMHRALASKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLLGNNIKPVVKVNI
ADQQHLTRIKMGNNPFFNEIFFQNFHE-VPAKFFEENISIEVVDSAASRSKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQRNKTTSGVRGYLKV-TICALGVGDQALVDQKL---PYEQ
-NTRVQIFKSKEVPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQFFIYCAEDLHFGT-------------------HKSATP
VLEVELIGDKLRTKPQN-PSDNPIWNQILTFQIQLPCLSSYIKFRVMDCSKYKCQDEIGS
ASLCLSQISSTG

ENSGT00550000074414_4_Linker_3_4 (493, 735)

EEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKPPFRT-S-EEGTCIMDAV-QHGLAYRGRIFV-EIVTKIKSQQDSV-MKDL---SQEV
TQV---EMQYYRQKYGLCVIFLSCTMMPKFKDLIQFEVSMG-HYGNKTDPNYKPLVSTTQ
---YSPVIYDG--TTYHYVPWYNTKPVVAVTSNWEDVGFRMNCLNLLHITRDRLKTNLDI
LKSI-RNPRD-PAL

PF08165 // ENSGT00550000074414_4_Domain_4 (735, 787)

LQQWEKLLKELQEDCRRPLPCMTD-QPRANSLDRNKWQLRSQLLQQ
LAQMAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPVNMVGTAKEWLH-----------------RLNAVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VLIWLMSRQQRVAYARVPAHTVLFSPAGPLSSGKFCGKIQNILLQYPEG---------EG
Q-DTFPASLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVKYSKNLKLLQQGSMVVYAET---YENQAKTRDDWGQQGLYHC
PNFSDVMGRKALPKTDFKAPPGWHWKDDWVVEPQRRLLLDIDINKSQVLEEVYENQLRNA
TGAWVPAAIPNTDVNGQPVEALENVKCPQGWHFKKNWIVKLNHAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRVRFRNHKELGQERSQE-QETLSFLQMQDLS--EE-GKE
GWEYGTF-DSRFHLDPQPTSRFRRRCWHRQLAPNKDRGVASIFLLEGSLAVEQK------
-------------------------------DQ-P--RKEMEKTRSWQ--P-WKD-LRHT
--------PEDP-RIPTTPFIYY-ILNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1386)

QLFCYIYQARNLMYN-----QILTFQEP
FIQVVFLNHSLCTQTLRS---SAAPTWSQSIIFQHLLLFEDPKDTRENPPLVVLELWQHD
SRG-N

ENSGT00550000074414_4_Linker_6_7 (1386, 1594)

KILWGRSMWPPVVWLGLQD---------------WVFTPLRWHPLVRELGEEEGE
ILASCELILETQKL---------------K-ELHPPILSIPCKDGIYLLPKNIQPTMKMM
AIE---------------------------------------------------------
---------IMAWGLRNMTK-----VRYPQLLL

PF00168 // ENSGT00550000074414_4_Domain_7 (1594, 1665)

ECGGESLKTEPISNFQENPNFPTSTFF
F------TVFMPLEETHAQPLVVKVVDNQEYGQQIVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWSLN----
---------------YTTVKLPT--LSVKKPD-----TFLDFVYK--KFWFDSSKDEEVY
E--EEVDWWSKLF--WATGDAD---KSLNYNHKSYHTLKVYDCELEAVLTFKGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPEAPKPPRQFSAWPEIEDFPQMCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYY--PNTLDPIFGMMYELTCNIPLEKD
LEIQLFDFDLITADDEIGSTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2128)

LLSGFGARCGLSKSYCKSGP--FKWRDQMTPSY
LLYRYAKQKG-LPPPVFDLEGDSLYYNGETFKLQSFESAPPTYKHLGPKKERLALYILNT
QGLVPEHVETRTLHSNSQPGIDQGKIQMWVDIFPKMLGPPGPQVNISPRKPK--------
-RYQLRCIIWSTAEVDLVQETFSKEKM

PF00168 // ENSGT00550000074414_4_Domain_9 (2128, 2231)

SDIYV-KGWLFGLEEDTQKTDVHYHSLTGEATF
NWRFIFTMDYLTTERACVQSQKDYIWSLDPTSTKFPARLMIQIWDNDFFSPDDFLG--VL
ELDLSDMPLP

ENSGT00550000074414_4_Linker_9_10 (2231, 2279)

AQNIKQCSLKMMETDSKWPF-TPQKRISLFKKTNVTGWWPCQVLD-GD

PF16165 // ENSGT00550000074414_4_Domain_10 (2279, 2371)

KW
RLSGKVKMTLEMLSEREALIRPAGRGQSEPNQFPMLHPPERNDSFLLWYQSPIKNFCYAV
CKRYRSKIICLVVTLVIGFILLNFVYSAPSYFAMNWIKPQLRLSSPIKIV-NLIGTVNTS
NINSSILTMEG----------STYH----------ASH------VFPEAPAP---

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-----------------IQK-----ANSPWLLVECGGETLETAQIKDYHSNPNFPQAALL
L-------TFLPQEEAYAPPLVLKVVDQQNFGIQMVVGQAIVYCLRPYFCDPWAEG----
---------------YVPPRLP-----------------------------------EDH
M--HEVDWWSKMF--WASGESP---KKWNH-KKDYYALKVYDCELEAIPDFQGLQDFCQT
FNLYNGEKTEDSPVV-GEFKGLFRIYPLSENPKQPSPPRQFQNLPERESGPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYV
IRGINLQPKDNNGLCDPYVILKLGKTVLGSRHHYK--PNTVDPVFGTVFELNCTIPLEKD
LEITLFDFDLILPDDKIGSTVIDLENRLLSNFGARCGLPKSYCLSGP--FRWRDQLTPSH
LLERYAHRKG-LPPPDFSTE-NCVTFSGRTFKLHNFERHTPPIKYLGSPKERLALYLLQA
QGQVPEHVETRTLYSNTQPGIDQGKVQLWVDIFPLHLGPPGPAVNISIRTA---------
KRYELRCIIWETRNVDLQDITITGERMSDIYI-KGWMHDMEDDMQKTDIHYRSLTGSGYF
NWRFIFPFNYLXXXXXXXXXXXEYIWSLDPTVEKIPP

PF00168 // ENSGT00550000074414_4_Domain_9 (2198, 2221)

RLLIQVWDNDKFLPDDFLG--IL
ELDLCEMPTPARKSQECTLSMMENKPKLPFKVLHKHVSLFRQKTITGWWPCQVLD-KGKW
RLSGKVKMTLEVLTEREAQERPAGRGRSDPNQYPTLHTPIRPETSFLWLLSPAQR--YIL
WNHYRRKLTYTLFMMGMLFLVIMFVYSTPSYLAMKLIKPEFQLDLYLARLGKSQKDI-NN
YPQRLSTQSQT----------------TH---TSPQ-KSTNFLDIFSALPAPEDN

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEK
DSFLQVTLQDMGSQKKE-----------------SFIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHQ--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 260)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKIGNNPFFNEVAH----S-FSFFFFFETESR-----------------STD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKL---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLSESP---------------EKQQSVNL
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGARIPDSV-RDGLAYRGRVYL-ELITQIKSYQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLVHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 786)

HQWEKLLRELVEDCKRPLPCMTD-QPKATSLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHCGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNITDSKDLQLLRQGDTAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDA
RGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGA----LSRE-QETVSFLQL-GPA--EG-EEE
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLAPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKYRAG--KEEDSKPWPWGLDR-Q--FRDPP
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQN---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLAMWDGGGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----TVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPR--LSEKKHQ-----DFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPEDPEAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRATNLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPVFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPDEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2233)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPLPAQ

ENSGT00550000074414_4_Linker_9_10 (2233, 2295)

HAKQCSIRMMDADPKWPHFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
RLDLAKSLFLSRSR

PF16165 // ENSGT00550000074414_4_Domain_10 (2295, 2372)

EEEALIKPAGRGQSEPNQYPTLHPPLRPHTSFMWLRSPVQHFCSVF
WKRYRFKLIAFVVILIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSNIFPELPAPED-

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 109)

LRLVVESAKISPPLSPPPKPCVTVYFRAMKKRTRVEEGNDPIWNET-LIWYLWNQPLEN
DSFLQVILRDAGSKKKE-----------------RFIGLATVLLKQLV

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KRPNEVLFVKNL
ILLNHSMRPTDCTVTLQVAQ---------------IHVQ--------------DTEMTDD
EELLSSTTNKMTQKKLTVPGL-TMHRALATKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 303)

QVRLKVFEARQLLGNNIKPVVKINI
GGHQHLTRIKMGNNPFFNEMFFQNFHE-VPAKFFEENILIRVVDSAASRSKAEIGRFQID
IGFIYHSPGHTLLRKWLGLCQRNKTTSGVRGYLKV-TIYALGVGDQALVDQKL---PYEA
-DTQVRIFKSAAVPI-SLAYLQFF

PF00168 // ENSGT00550000074414_4_Domain_3 (385, 492)

IYCAEDLHFT------------------------AP
ALEVELIGDKLRTYPQS-QNDSPIWNQILTFQIQLPCLSTYIKFRVVDCSKHDCWDEIGS
ASLCLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKRARFRT-P-EEGTCILDAV-KDGLTYQGRIFV-EIITQLKSQQDSV-IKDL---SREV
TQI---ERQQYRQKYGLCVIFLSCTMMPKFRDLIQFEVSMG-HYGNKMDPTYKPLVSTTQ
---HSPVIYDG--TIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHITRDHLKANLDT
LKSI-RNPKD-PAML

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 787)

QQWEKLLKELMVDCRRPLPCMTD-QPMANSLDRNKWQLRSRLLQQ
LAQRAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRNMVVTAEDWLR-----------------RLNAVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VMIWLMSRQQRVAYARVPAHTVLFSPAGPLSSGKFCGKIQNLLLQYPEG---------EG
Q-DTFPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVLHSKNLKLLQQGNMVVYAET---YENQAKFKDQWGQQGLYHC
PNFSDVMGRKAVPKTDFKAPPGWRWQGDWIVEPQRRLLLDIDINKSQVLEEVYENQIRNA
TGAWVPAAIPTTDVNGQPVEALENVKCPQGWHFKKNWTVELNHAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRVRFRNHKELGQELSQE-QETLSFLQKQDLS--EE-G-E
GWEYGTF-DSKFHLDPQPASRFRRRCWHRRLAPKKERGVAPIFLLEGSLAVTLE------
-------------------------------NE-A--KKEHEKTWSWQ--H-WRDSWRHI
--------PEDP-RIPTMPFIYC-IFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1386)

QLFCYIYQARNLMYN-----QILTFQEP
FIRVVFLNHSLCTQTLQS---SAAPTWSQTLIFQHLLLFENPKDTRENPPLVVLELWQHD
SRG-N

ENSGT00550000074414_4_Linker_6_7 (1386, 1589)

KILWGRSMWPPVVWLNLQG---------------WAVTPLRWHPLVRELGEEEGE
ILASCELILETEKL---------------K-DRHLPILSVSCKNGIYTLPKNIQPAVKMM
AIE---------------------------------------------------------
---------IMAWGLRNMKN-----VHY

PF00168 // ENSGT00550000074414_4_Domain_7 (1589, 1664)

PQLLVECGEACLRTEPISNFQENPNFPKTNFF
L------TVFMPMEETHALPLVVKVVDNQVYGQQIVVGQANID

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWALS----
---------------YTPVKLPT--LSVKKPD-----TLFDFFFK--KFWFDSSKEEDDY
E--HDVDWWSKLF--WATGDTD---KSLQYKYKSYHSLTVYDCELEAVQAFQGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPDAPKPPRQFSSWPETEDFPQTCM

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGNRDLYY--PNTLDPIFGTMYELTCNIPLEKD
LEIQLYDFDLVTADDEIGSTVIDLENRLLSGFGARCGLSTSYCKSGP--FRWRDQLSPSY
LLDRYAKQKG-LPPPVFDLDNDSIVYNGKTFRLQSFESTPPTFEGLGPKKERLALYILNT
QGLVPEHVETRTLYSKSQPGIDQGKIQMWVDIFPKMLGPPGPRVNISPREPK--------
-RYEVRCIIWSTSQVDLVRQTLSREKMSDIYV-KGWLFGLEKDMQKTDVHYHSLTGAADF
NWRFIFTMDYLVTERVCVQSQKDY

PF00168 // ENSGT00550000074414_4_Domain_9 (2185, 2233)

IWSLDPTSQKFPARLIIQIWDNDLFSPDDFLG--VL
ELDLTDMPLPAE

ENSGT00550000074414_4_Linker_9_10 (2233, 2277)

RSKQCSLKMLETDSKRPS-TQQKRFSLFKKTNVTGWWPCQVHD-

PF16165 // ENSGT00550000074414_4_Domain_10 (2277, 2372)

GEKW
RLSGKVKMTLEILPEREALIRPAGRGQSEPNQFPTLHPPIRNDSSLLWYRSPIKNFCYVF
CKRYRYKIICFSVILAVGIILFNFVYSTPNYLAMAWIKPELRLNPPIKIV-NLIGSVNTS
RINSSVFSMEG----------SKLHPLKDHGPTFLQGSRRQMRDVIPEMPAPQG-

MLRLVVQSAKID

PF00168 // ENSGT00550000074414_4_Domain_0 (13, 109)

PPLAPLPRPCMSIDFRDIKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDMGSQKKE-----------------RFIGLATVLLKPLL

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSNQ--------------DIEKTGA
EDHLGITAREAARQKLMVPGS-TAYRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKL---LYGT
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQLFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCRKKDCPDEIGT
ASLSLNHISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEGKQSLEP-------------TSYAPRVYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITQIKSYQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---HSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLY

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLRELAEDCKRPLPCMTY-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPKDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAEM---YENQAKYKDQWGQQGLYHC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDT
RGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVVELNHAVD--SWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSQE-QETLSFLQL-GLA--KG-EEE
GWEYDTF-GSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSLACEAGS--V-R
EEGDWAWARGNRSSTQEPQGRLSWVQAMDLKYHAG--KEEDSKTWPWGLDR-Q--FRDPQ
--------RQDT-QPPNLPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1572)

QHLLLYENPQDTKENPPLVVLELWQRD
FWG-KESLWGRSVWPPMVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIE---------------------------------------------------------
---------IL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----TVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YMHPKLPT--LSEKKHQ-----DFLGYLYR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSG
HRYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHHHSLTGEADF
NWRFIFTMDYLAAERMCVQSQKDY

PF00168 // ENSGT00550000074414_4_Domain_9 (2185, 2230)

IWSLDATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDADPKWPYFVQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLQSPVQNFCYIF
WKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIINSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SDIP
---PMDLCVSG--NIYHYVPWYNTKPVVAVTSHWEDVSFRMNCLNLLHVTRDRLKANLDT
LKSM-RNPKD-PALLLQWEKLLKELLEDSQHPLPCLTD-QPKATELDKKRWELRSRLLQE
LARQAKEAK--FKPKDMVATVEGWLY-----------------RLNSVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 918)

PQM--SLPD
VMIWLVSKGQRVAFAQVPAHAVLFSQAGPLQSGKFCGKTQTLLLQYPEG---------EG
QKDTLPAHLRVCMWLGN

ENSGT00550000074414_4_Linker_5_6 (918, 1294)

VEDSKDLKLLRHGNVVVYAET---YENQAKYKDQWGQQGLRHC
PNFSDVIGHTSLPKEDFQVPPGWHWQGKWMVEPQRRLLLDADINKSQVLEEVYENQRRDI
TGAWVPAAIPNTDVEGNFMEARENMKCPRGWYIQKNWTVELNHAVD--SWEYGAGVPPAG
LPPAWNSVEKTYHSVRRRRWVRMRFRSPQK----LSHE-QETLSFLQLHSPS--VAKEDE
GWEYGTF-GSKFRLNPQPTSQFRRRCWHRRLAPNKDRGVAPIFLLEGSLVPVGGA--CER
RGLMWAWAG-DRKSTQEPQAL-----GMDLTQQAKEKEKEEDRTSLWGINKMLSNIWRPT
--------PENT-QPSNMPFIYC-TFNKPHYYQ

PF00168 // ENSGT00550000074414_4_Domain_6 (1294, 1393)

LFCYIYQARNLKPN-----QIQRFQGP
FIRAVFLNHSQRTRMLSS---STAPTWAQTLVFLHLLLYENPQDTKDSPPLVVLELWQQD
SRG-KESLWGRSMWSPVVWLDLQD---------------RTLPPMRWHPLVKQMGEEEGE
ILASCELILETQSV----------------REKKPPILSVPWKDKVYMLPKDIQPTLKKM
AIE---------------------------------------------------------
---------VLVWGLRNMKN-----VRSPYLLVECGEQSLRTEPIKDFQTNPNFPQSALF
F------TLFMPIEEAYSLPLMVKVVDTQDFGQQTVVGQANIDFLQPYFCDPWADN----
---------------YVPPRLPT--LSMKKHQ-----ELLGYLYE--KLWLNYHKAEDEY
E--HDVDWWSKLS--WATRDAP---KSLKYKDKDYHTLKVYDCELEAVPDFRGLQDFCQT
FRLYKEKPVLDSPVV-GEFKGLFRIYPFPEDPKATKPPRQFLVWPEREGFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYV
VRAFSLQPQDYNGLCDPYVILKLGQKQIGNRDTYQ--PNTLDPIFGTMFELSCNIPLEKD
LEIHLYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSY
LLERHAKLKG-LPPPLFDSEDNSVFYNGKKFKLQSFEPTPPTAQDLGPEKERLALYLLHT
QGLVPEHLETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNISPRKPKSKASGRSG
CRYELRCIIWQVSNVDLQDSNYSGEKTSDIYV-KGWLLGLEKDMQMTDIHYCSTTGKGYF
NWRFIFTMDYLAAEQMCIQSQK

PF00168 // ENSGT00550000074414_4_Domain_9 (2183, 2216)

DYIWSLDPTSLKFPPRLIIQVWDNDILSSDDFLGPGVL
ELDLADMPFPARYAKNCSIRLMDTEPKWPHFHQHKHVSLFKKKIVTGWWPCQVLD-SGKW
RLSGKINMTLEMLTEDEAALKPAGRGQSEPNRYPTLQPPIRLDSTLRWVLLPMQNLWQYI
WKHNRKKILALFVILVILFMLFNFIYATPNYLAMNLIKPGVQDTYEGLRRFWLVCSEITS
NKKGRVV------------------------------------------------

MLRLV

PF00168 // ENSGT00550000074414_4_Domain_0 (6, 109)

VQSAKIDPPLAPLPRPCVSVDFRDVKKRTSVVEGNEPVWNET-LIWHLWNRPLEN
DSFLQVMLQDMGSQKKE-----------------RFIGLATVLLKPLL

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KQPSEVPFVKDL
TLLNHSMKPTDCTVTLQVAY---------------ISNQ--------------DIEKTGA
EDLLGITARETARQKLMVPGS-TVHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVRVSI
GGQKHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILL-----------------QTD
VGFIYHSPGHTLLRKWLGLCQPNNPSSGVRGYLKV-TICALGVGDQALVDQKL---LYGA
DDTDIQIFKSAAVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLKK-------------------HQSMNP
QLEVELIGKKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRILDCHRKDCSDEIGT
ASLFLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITEIKFHQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPSFKDLIQFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIHDG--NIYHYVPWYDTKPVVAVTSNWEDISFRMNCLNLLHFTRDRLKVNLDT
LKSI-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 787)

HQWEKLLRELAEDCKHPLPCMTD-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPRDMVATVEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPAGVLHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKNLQLLRQGDTAVYAEM---YENQAKHKDQWGQQGLYRC
PNFSDVMGKKTLPMTDFQPPLGWHWQDNWTVDPQRRLLLDIDINKSQVLEEVYENQVRDA
RGTWGPATIPNTDVNGQPMEARENVKCPQGWHFKKDWAVELNHAVDSKGWEYGMDIPSLG
QPQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QEALSFLKL-GLV--ED-EEE
GWEYGTF-GSRFHLNPQPQSKFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDVKY-AG--KEEDSKTWPLRLDR-Q--FRDPL
--------RQDT-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1390)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQHD
SWG-KKSLW

ENSGT00550000074414_4_Linker_6_7 (1390, 1572)

GRSMWPPLVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILETEKL---------------R-EKQLPILSIPWKNGAYTLPKNIQPTIKRM
AIEVLAM-AGRGR----G---LECAAVLLVLPDYGIQSLH-PKKDYL-GVGGRQ--E---
-----RNEEIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPHLLVEFGEESLKTEPIRDFQTNPNFPES--V
LVL----TVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1857)

LQPYFCDPWAPD----
---------------YMHPKLPS--M------------FLGYLYE--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSPKYEYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1948)

RVYV
VRAINLQPQDYNGLTPVR----A-----GGTETWPTASAVSNTLIPRMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPQTPTLHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNIKPRKPK--------
-RYELRCIIWKTANVDLVDENLSREKTSDIYI-KGWLYGLEKDMQKTDIHYYSLTGEANF
NWRFIFTMDYLATEHMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDTFTPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDANPKWPYSLRYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2373)

LSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLRSPVQHFCYIF
WKRYRFKFVAFMVILIIALMLFNFIYSAPHYLAMNLIKPHLQLYPPIKIF-NIITSVNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPRIHLSDIFPELPAPQD-

MLRLVVQSAKIDPPLAPLPRPCMSIDFRGESLPGS-----------------TWEREAPR
G-----------------------------------------------------------
------------------------------------------------------------
----------------------------NMHSVKKE

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 265)

VRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNSGSGVTGYLKV-TIYALGVGDQALIDQKL---LYGT
DDTDIQIFKSAVVPM-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQLFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQVCLRS-----VFLSSRKKDCPDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITQIKSYQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLY

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLRELAEDCKHPLPCMTY-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPKDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSILFSPAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAEM---YENQAKYKDQWGQQGLYHC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDT
RGAWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QETLSFLQL-GLA--KG-EEE
GWEYDTF-GSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDLKYHAG--KEEDSKTWPWGLDR-Q--FRDPQ
--------RQDT-RPPNLPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLVSN-----QIVTFQAP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1572)

QHLLLYENPQDTKESPPLVVLELWQRD
FWG-KESLWGRSMWPPLVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLAMWDGDGGQDRRGWSGVRCSLLLVLPDYWIQSSHPEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----TVLMPTEEAYALPLVVKVVDNWAFGQQIVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YMHPKLPT--LSEKKHQ-----DFLGYLYR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK--------
-RYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEADF
NWRFVFTMDYLAAERMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDADPKWPYFVQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLRSPVQNFCYIF
WKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIINSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD-

MLRLVVESARIE

PF00168 // ENSGT00550000074414_4_Domain_0 (13, 110)

PPLSPPPRPCLTVYFRDIKKRTRVVEGNDPTWNET-LIWHLWSRPLEN
DSFLQIILRDMVPKKTE-----------------RFIGLATVLLKPLVQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

KPRKVLFVKDL
TLLNHAMMPTDSTVNLQVAH---------------VTHW--------------DSEKTGG
GDPLGITTKEAVQQKFPIPGSTGMPRILSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLMGNNIQPVVKVTI
AGQQYHTRIKMGNNPFFNEIFFQNFYE-VPAKFFEEIII--VLNSSAMRSKAEIGRFQTD
VGFVYHSPGHTLLRKWLGLCLLNEPGSGVRGYVKV-TICVLGVGDQALVDQKL---LYGA
-DTDVEVIKSAAVQT-TMAYLQLFIYCAEDLRGAG-------------------QEVP--
-------QILK

PF00168 // ENSGT00550000074414_4_Domain_3 (432, 487)

GTKVRH-QTDNPIWNQVLTFQIQLPCLSTT-------DKRNDCLEEIGA
ASLSLS

ENSGT00550000074414_4_Linker_3_4 (487, 737)

HISSTGEEIEG-------------------------LYSGFLPCFGPCFLPLHG
GPQAPMRI-Q-EEAASIPDPV-GDGLSYRGRVLL-ELTTQIKSHQGST-IKDL---SHEV
ARI---EKHQNRLKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSATQ
---YSPVIYDG--NIYYYIPWYNTKPVVAVTSNWEDVSLRMRCLNLLQFARDRLKANLDT
LRSM-RNPRD-PALLP

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLQELMEDCRRPLPCMTD-QPRATDLDRKRWELRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRDMVPTVEGWLR-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQR--SLPD
VMIWLIAKEQRVAFARVPAHTVLFSPAGPLHSGRFCGKIQTLLLQYPEG---------EG
QQNASPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GDVTDSRDLQLLRHGDLVVYAET---YENQAKYKDQWGQQGLYQC
PNFSDVMGHKALPKSEFKAPPGWHWQDSWRVEPQRRFLLDIDINKSQVLEEVYENQDRDS
TGTWVPSATPNTDVNGHSVPARDTVTCPKGWHFKKNWAVELNHAVDSEGWEYGVGIPPSG
LPRVWTSVEKNYHSSRRRRWVRMRFRNHND--DELSLE-EQTVSFLQMQGLA---DAGEE
GWEYGSL-GSRFHLDPQPQSRFRRRCWHRRLALNIDTGVAPIFLLEGSLAMDLKQ-----
-----------------------------------KRKKDESKARAW----------TQA
--------QGDQ-RLPTMPFIYY-TLHKPHCY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLISK-----QIVAFQGP
FVRVVFLNYSQCTQHRPS---SSAPTWAQTLIFQHLLLHESPQDTQKSPPLVVLELWQRD
AQG-KESLWGRSMWPPVVWLDLRD---------------WMLPPLRWHPLVKELGEEECE
IFASCELILETEKL----------------KEKHLPLLSIPWKDGAYTLPKSIQPTMRKT
AIE---------------------------------------------------------
---------VLAWGLRNLKR-----ARYPQLLVECGGESLQTEPIEDFLANPNFPESALL
L------TVYMPMEEAYTQSLVMKVLDNQNFGQQTVVGQASVDFLQPYFCDPWAPD----
---------------YLPG------------L-----QVIGFLYD--KFWFKPGKAEYEY
E--YEVDWWSKLF--WATGDD----KSLKYKYQSYHTLKLYDCELEAVPAFQGLQDFCQT
FKLYQEQPKADSPVV-GEFKGLFRIYPLPENPEAPQPPRQFLAWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYM
VRAINLQPQDYNGLCDPYVILKLGSTKLGSRDKYK--PNTVDPIFGTMFELTCTIPLEKD
LHIQLYDFDLFSHDDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2170)

LLSGFGARCGLSKSYCQSGP--FTWRDQMPPSF
LLERYAKRKG-LSPPVFDPEGDSVLYSGERFTLQNFESEAPTVPGLGPKKERLALYILHT
QGLVPEHVETRTLYSDSQPGVDQGKVQMWVDIFPQKLGPPGPPVIISTREPK--------
-RYELRCIIWKTAQVDLVDEALSREKMSDIYV-KGWLFSLEKDMQKTDIHYHSLTGEAIF
NWRFIFTMD

PF00168 // ENSGT00550000074414_4_Domain_9 (2170, 2228)

YMAAEHVCIESHKDYIWSLDPTSTKFPARLIIQIWDNDTLSSDDFLG--VL
ELDLSDM

ENSGT00550000074414_4_Linker_9_10 (2228, 2282)

PYPARHAKQCSLHMLDTEPKWPHSLPHERISLFKKKIVTGWWPCQVQE-DDKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEVLSEKEALTRPAGQGQSEPNQYPTLHPPLRASSAFMWLRSPIRTLCLGL
CKRYRCKILTFLLLLGIGFLLFKFIYSAPNYLAMNWIRPGLRMQTPIKIY-NLLTSPTVS
NASPSPAATQA----------PSLQPSTNHQLPLLQAPNQHLDDIYPELPTP---

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 110)

LRLVVQSAKINPPLSPSPKPCLTIYFRDMKKRTRVEEGNDPIWNET-LIWHLWNQPLEN
DSFLQVILQDAGSKKKE-----------------RFIGLVTILLKPLVQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

NPNEVLFVNNL
NLLNHSMMPTECTVTLQVAQ---------------IHHQ--------------DIEKTDN
EDLLGITTREMAQQKLMVPGV-IMDKTLSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 301)

QVRLQIFEARQLLGNNIKPVVKITI
AGKQHLTRIKMGNNPFFNEIFFQNFYE-VPAKFFDETILIQVVNSSATRSKAEIGRFQTD
IGFIYYSPDHTLLRKWLGLCQRNKASSGVRGYLKV-TICALGVGDQALVDQKP---PYA-
-GTQIQIFKSTSAPI-KLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQFFIYCAEDLHFRK-------------------QQSVNL
VVEVELIGDKLRTKQQMYSIDNPIWNQILTFQIQLPCLSSFIKFRVLDCSRGDCQEEVGK
VSVCLNHISSTG

ENSGT00550000074414_4_Linker_3_4 (493, 734)

QEIEG-------------------------MYSGFLPCFGPSFLILRG
GKKAPFRI-P-EEGTCISDSI-KDGLAYRGRIFV-EIITQIKSYQGTV-IKDL---SHEV
TKV---ERQQYRQKYGLCVIFLSCTMMPNFKDLIQFEVSMG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAITSNWEDVNFRMNCLNLLHITRDRLKANLDT
LKSI-RNPRD-PA

PF08165 // ENSGT00550000074414_4_Domain_4 (734, 786)

LLQQWKKLLTELTEDCQCPLPCMTD-QPKATQLDKKKWKLRSLLLQE
LAQQA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KEA----QPRNIVATVEGWLH-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VMIWLMAKEQRVAYARVPAHTVLFSPGGAQHSGKFCGKIQNLLFQYPEG---------EG
QKDTLPAHLRICMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLQQGNMVVYAET---YENQAKYKDEWGQQGLHHC
PNFSDVMGRKALPKSDFRAPPGWHWQDNWIVEPQRRLLLDIDINKSKVLEEVYENQSRDA
KGPWVPAAIPNTNVNGQPVEATENVKCPQGWHFKNQWIVELNHAVDSEGWEYGVGIPPLG
LPQIWSSVEKTYHSCRRRRWVRVRFRDHSEL----GLE-QETLSFLQLQGLA--NE-GEE
GWEYGTF-GSKFHLDPQPTSRFRRRCWHRRLAPNKERDVAPIFLLEGSLVK---------
-------------------------------DT-P--TKEPEMRRSWH--Q-FKEFLKRT
--------PEDP-RIPTMPFIYC-ILNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1381)

QLFCYIYQARNLISN-----QILTFQGP
FIRAVFLNHSLCTQTLQN---STAPVWAQTLIFQHLLLFENPQDTKESPPLVMLELWQHD

ENSGT00550000074414_4_Linker_6_7 (1381, 1589)

SRG-KEILWGRSMWPPVVSLDLQG---------------WVLAPLRWHPIVKEFGEEEGE
ILASCELILETEKL---------------T-ETQLPILNIPWKNGIYTLPKDIQPTLKLM
AIE---------------------------------------------------------
---------VLAWGLRNMNK-----VHY

PF00168 // ENSGT00550000074414_4_Domain_7 (1589, 1664)

PQLLVEYGEKSLRTEPISNFQTNPNFPTSIFF
L------MVSMPVEEAFALPLVVKVVDNQDYGQQIVVGQANIN

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWALN----
---------------YRPPKLPS--T------------FLG-YIQ--KFWFKSSKNEDEY
E--HDVDWWSKLF--WATGDAN---KSLKYKYKNYYTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKVDSPVV-GEFKGLFRIYPFPEDPEAPKPPRQFLVWPQNEDFPQMCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
VRAINLQPQDYNGLCDPYVILKLGQMKLGSRDSYQ--PNTLDPIFGMVFEFTCKIPLEKD
LQIQLYDFDLITSDDEIGSTVIDLENRLLSGFGARCGLSKSYCQSGP--FKWRDQMSPSY
LLEHYAKQKG-LPPPVFDQEEDSVLYNGKKFMLQSFESKPPTFQGLGPKKERLALYILHT
QGLVPEHVETRTLYSNSQPGIDQGKVQMWVDIFPKMLGPPGPQVNISPRKPK--------
-RYELRCIIWSTAQVDLVHKTLSRDKMSDIYI-KGWLFGLEKDMQKTDIHYHSLTGEATF
NWRFIFTIDYLAAERMCVQSQKDYIW

PF00168 // ENSGT00550000074414_4_Domain_9 (2187, 2235)

SLDPTSTKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPLPAQST

ENSGT00550000074414_4_Linker_9_10 (2235, 2282)

KQCSLRMLETDSKWPH-LQHKRISLFKKNTVTGWWPCQVQD-KEKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEILSEQEALIRPAGRGQSEPNQYPTLHPPLRNESSFIWFRSPIKNCCYVI
CKRYRSKIICLFLIFILGIILFNFIYSAPNYLAMTWIKPELRLNPPIKIV-NVIGSIKGK
RINSSIFNSEN----------LHRQRVTTHKPS----------------------

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--------------MQT

PF00168 // ENSGT00550000074414_4_Domain_3 (438, 481)

-QTDNPIWNQILTFQIQLPCLSSYIKFRVLDCHRKDCSDEIGT

ENSGT00550000074414_4_Linker_3_4 (481, 738)

ASLSLNQISSTGEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGAHIPDSV-RDGLAYRGRVFL-ELITQIKSCQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNIKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLCQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 786)

WEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAENWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIQTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDT
RGAWGPAAIPNTDVNGQPIEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLQLQGPA--EG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGIAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYYQLF

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1386)

CYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQHLLLYENPKDTKESPPLVVLELWQRD
SWG-K

ENSGT00550000074414_4_Linker_6_7 (1386, 1572)

ESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIE---------------------------------------------------------
---------IL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1660)

AWGLRNMKK-----ASSPQLLVEFGDESLRTEPIRDFQTNPNFPESESV
LVL----LVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ANIDFLQPYFCDPWAQD----
---------------YVHPKLPR--LSGKKHQ-----DFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVDINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIW

PF00168 // ENSGT00550000074414_4_Domain_9 (2187, 2216)

SLDATSMKFPARLIIQVWDNDIFSPDDFLGSGVL
ELDLSDMPLPARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
RLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFMWLRSPVQHFCSVF
WKRYRFKLIAFMIISILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTR--------------------------GPTNHLSNIFPELPAP---

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WEKLGITCKEGGRHEVMVAGH-SVKMPLTSKPQDFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 260)

VQVRIFEARQLHGNNIAPVVKILI
GNHEYRTRIKKGNNPFFSEVG---------------------------------------
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MLRLIVESAKIEPPLSP

PF00168 // ENSGT00550000074414_4_Domain_0 (18, 100)

PPKPCVAVNFRDTKKKTRVVEGNEPIWNET-LIWHLRNRPLEN
DSFLQVVLLDMGSKKKE-----------------RFIGL

ENSGT00550000074414_4_Linker_0_1 (100, 217)

ATVLLEPLVK-RTEVLYVKGL
ILLNHSMKPTDCTVTLQVAQ---------------MTNQ--------------DIEKTWD
EDLLGITAREAARQKLMALSP-TLHRVQCSKPQHFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 297)

VRVKVYEARQLMGNNIRPVVKVII
GSQQHHTRIKMGNNPFFNEEKGTVFLK-SRLEILDEIISIQVMNSSVLRYNAEIGR

ENSGT00550000074414_4_Linker_1_2 (297, 300)

FQT

PF08151 // ENSGT00550000074414_4_Domain_2 (300, 365)

D
IGFIYHSPGHALLRKWLGLCLPNKPISGVRGYLKV-TICVLGVGDQAPVDQKL---PYGA
-EKD

ENSGT00550000074414_4_Linker_2_3 (365, 387)

IQIIKSTRVPI-HAAYLQFFIY

PF00168 // ENSGT00550000074414_4_Domain_3 (387, 481)

CAEDLHLTFPFHLKKKMLKSFNFLFIEKHHLVSP
VLEVELIGEKLQTNMQT-LTDNPIWNQILTFQIQLPCLSSYIKFRVLDCPRNDCQNEIGT

ENSGT00550000074414_4_Linker_3_4 (481, 728)

VSLSLNQISSTGEEIEG-------------------------MYSGFLPCFGPSFLILHG
GKRAAFSM-Q-EKHAKMQGAG-NDGLAYRGRLFM-ELITKIKSQQEFW-IKDI---SREV
ARI---EKHQNRLRYGLCVVFLSCTLMPSFKDLIQFEVSIG-HYGNKTDTNYKPLVSTTQ
---YSPVIYDG--NNYHYVPWYNTKPVVAVTSNWEDISFRMKCLNLLHVTRDRLKANLDT
LKSL-RN

PF08165 // ENSGT00550000074414_4_Domain_4 (728, 788)

LKD-PALLQQWEKLLRELVEDCKRPLPCMTD-QPKANILDKEKWQLRNLLLKE
LAEKAKN

ENSGT00550000074414_4_Linker_4_5 (788, 832)

A----KPRDMVATVEGWLH-----------------RLDAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GFPD
VMIWLMAREQRVAYARVPAHTILFSPAGSLHSGRFCGKIQSLLLQYPEG---------EG
EKDTVPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GNVTDSQHMQLPRQGSIVVYAET---YENQAKYKDQWGPQGLHRC
PNFSDVTGHKALPKTDFKAPIGWHWQDNWKIEPQRRLLLDTDINKSQVLEEVYENQDRDA
TGAWVPAEIPNTDLDGQPVEARENVKCPPGWHFKKNWTVELNHAVDSEGWEYGVGIPPSG
MPRVWSSVEKTYHSQRRRRWVRLRFRDPEK----PSQE-QETLSFLQQQGLA--KE--DE
GWEYGTF-GSKFHLDPQPHSKFRRRCWHRRLVPNHDKGIAPIFLLEGSLF----------
-----------------------------------------------------RNSWRDR
--------PEES-PPANMPFIYC-LINKPHYYQLL

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1390)

CYIYQARNLLSN-----QILTFQGP
FIRVIFLNHSQRTQAAGS---SAAPIWAQTLIFQHLLLYENPQDTKESPPLLVLELWQRD
SQG-KESLW

ENSGT00550000074414_4_Linker_6_7 (1390, 1594)

GRSIWPPVVWLDLQD---------------RILPPLRWHPLVKDLGEEEGE
ILASCELILETEPALAQLSPLR--NLLQKLREKQLPILSVPWKNGVYTLPRSIQPTQRKM
AIE---------------------------------------------------------
---------ILAWGLRGMKK-----MRYPQLLV

PF00168 // ENSGT00550000074414_4_Domain_7 (1594, 1660)

ECGEESLKTEPIQDFQTNPNFPEPILF
L------MVLMPTEEAFALPLTVKVVDNQDYGQQTVVGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ANIDFLQPYFCDPWAQD----
---------------YVPPQLPSPDPVCVYPR-----APLQKVLVQVQQSIPPLPCQDEF
E--HEVDWWSKLF--WATAD-D---KSLSTSTKDYFTIKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKVDSPVV-GEFKGLFRIYPFPENPEAPKPPRQFLVWPSREDFPQQCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYV
VRGINLQPQDYNGLCDPYVMVKLGETKLGSRDSYR--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLVSADDEIGTTVIDLENRLLSGFEARCGLSKSYCQTGP--FRWRDQMPPSY
LLERRAKQKG-LPPPLYSPEEDSVLYNGEKFKLESFEPKPLHVPGLGPKKERLALYILHT
QGLVPEHVETRTLYNESQPGIDQGKVQLWVDIFPKKLGPPGPQVDISSRKPK--------
-WYELRCIIWKTASVDLVDESLTREKMSDIYV-KGWLFGMEKDMQKTDIHYHSITGEGNF
NWRFIFTMDYLAAECMCVQSEKDYIWSLDPTSMK

PF00168 // ENSGT00550000074414_4_Domain_9 (2195, 2216)

LPARLIIQVWDNDTFTSDDFLGAGVL
ELDLSDMPFPAPSAKQCSLRMMDPDPKWPQFLQHKRFSLFKKKIVTGWWPFQVLD-GDKW
HQSGKVKMTLEILSQKEALIKPAGRGQSEPNQYPTLHPPLRPDATFSWLRSPIQNFCIVF
WKRYRYKIIALSVILVMVLLLFHFIYSAPNYLAMNWIKPEMRLYPPIKIV-NVISSPNTS
NASSTLLITEK----------PVLVDTTDQEWQLVQEPKNQMDDIFPELPDTGD-

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 73)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDMG

ENSGT00550000074414_4_Linker_0_1 (73, 216)

SQKEERKKAFPWLGISHLLLVSHVIGLATFLAQPLWKQPSKVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHR--------------DIEKTGA
EDLLGITAREAARQKLLVPGS-TVHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 262)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHK-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTILRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKQ---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 494)

YLQFFIYCAEDLHLSESP---------------ENQQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISSTGE

ENSGT00550000074414_4_Linker_3_4 (494, 737)

EIEG-------------------------AYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGARIPDSV-RDGLAYRGRVFL-ELITQIKSCQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NYPP--------------SSWDY-RHVLPCLTNFCIFHRDRKANLDT
LKST-RNPKD-PALLC

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIHTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDTDINKSQVLEEVYENQGRDI
RGAWGPAAIPNTDVNGQPTEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLQL-GPA--EG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1569)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLMKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLATWDGDGGQGRWGWSGVSH---------------PEKDYLGG-GGRQQR--N---
-----EEV

PF00168 // ENSGT00550000074414_4_Domain_7 (1569, 1665)

VILAWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQASIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPS--------------TFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFMWLRSPVQHFCSVF
WKRYRFKLIAFMVISILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNSS
NASSSILPTQD----------PHLKPTIDHEWKLHPGPTNHLSNIFPELPAPED-

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------------------MK-----VRYPQLLVECGEESLRTEPISDFQTNPNFPESDLF
L-------TFIPMEEAYAMPLVVKVVDDQDYGQQTVVGQASIDFLQPYFCDPWAQD----
---------------YMPPRLPSKTLSVGLPP-----PFLGHIYE--KFWFKASQAEDEY
E--HEVDWWSKLF--WATGNDD---KSLNYKYKSYHTLQVYDCELEAVPAFQGLQDFCQT
FKLYQEQPQVDSPVV-GEFKGNFRIYPVPEDPELPRPPRQFLVSSEYEDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYI
VRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYH--PNTLDPIFGMMFEITCNIPLEKD
LQIQLYDFDLLSSDDEIGTTVIDLENRLLSGFGARCGLSRSYFQSGP--FRWRDQMTPSY
LLERYAKRKG-LPPPVFNLEEDSVLYNGKKFKLQDFETKTPTVHGLGHKKERLALYILHA
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPRVNISPRKPK--------
-RYELRCIIWNTAQVDLVHETLSREKTSDIYI-KGWLFGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAEHMCVQSQKDYI

PF00168 // ENSGT00550000074414_4_Domain_9 (2186, 2233)

WSLDPTSMKFPARLIIQIWDNDIFSSDDFLG--VL
ELDLSDMPLPAR

ENSGT00550000074414_4_Linker_9_10 (2233, 2278)

YARQCSLTMMDHDPKWPY-LQNKHVSLFKKKTITGWWPCQVHD-G

PF16165 // ENSGT00550000074414_4_Domain_10 (2278, 2372)

DKW
RLSGKVKMTLEMLSEKEALIKPAGRGQSEPNQYPTLHPPLRNNPAFMWLRSPIKNFCYVF
CKRYRFRIICTFVILVIMFTLFSFIYSAPNYLAMSWIKPELRLHPPIKIF-NLISSLNTS
NANSSILDTQT----------SDLEPVRDHEPILLKGFKNYLNGVFPELPAQN--

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----------------SMPFIYC-AFNRPHHYQLFCYIYQARNLSSQ------NQTFQGR
RPP--CRGPERCRGRVGTGRKGADPSPKTRD----LGRRPKSHEFQERPLEAPPGPWRRA
GGA-GGPPQ------GAAWVDWTRGSLSGRAPRRRWWGAVQAPQGRWGPRG-GWGAARGA
--------------PPLSEPRPPAPPLQSLREKTPPLLSVPWKDGVHLLPRGIQPTLRKM
AIE---------------------------------------------------------
---------ILVWGLRNLQK-----VRSPQLLVECGEEA

PF00168 // ENSGT00550000074414_4_Domain_7 (1600, 1661)

LRTEPVADFRSNPGFPQSTLF
F------TVFMPMEEAYALPLVIKVLDNRDFGQQSTVGQA

ENSGT00550000074414_4_Linker_7_8 (1661, 1857)

TISSLQPYFCDPWAG-----
---------------YTPPKPPGPGKAAPPPQQ--------------QSPSCPRPRQDEY
E--HDVDWWSKLF--WATDDTH---LSPKFKDKDYHTLKVYDCELEAVPGFQGLQDFCQT
VRLYQERPVLDSPVV-GEFKGLFRIYPFPEDPKALKPPRQLVVWSNREGWPQECLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYV
VRALNLQPQDYNGLCDPYVIVKLGDKTLGNRDKYQ--PNTLDPIFGTMFELSCSIPLEKD
LEIQLYDFDLLSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMHPST
LLERYAKRKG-LPPPLFNSKDDSVVYNGQLFRLQSFGKQRGGPPCARPQSEA-GLCVL--
GGWRPD---------PDQQPPAQGKVQMWVDIFPKALGRPGPPVNISPRTPK--------
-RYELRCIIWKTEDMDLQDINLSGAKSSDIYV-KGWLFGLEKDAQVTDIHYHS-TGEGTF
NWRFIFTMDYLAAEHVCVHSEKAYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2216)

PSTTKFPARLIIQVWDNDIFSPDDFLGAGVL
ELDLSDMPLPARHAKTCSIRTVDPSPRWPYLQPPKHVNLFKMKTVTGWWPCQVLD-GGKW
RLSGKVKMTLEMLTHKDAEVKPAGRGRTEPNQYPKLHPPLRADHSWMRLHSPLRGVCHVL
WKRYRLRILSCFLALFLVIMLFQFIYATPNYMALSWVKPHL-------------------
-------------------------------------------------------

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEK
DSFLQVTLQDMGSQKKE-----------------SFIGLATVLLKPLWKQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHQ--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TAHRALSSKPQHFQVRTLQLSG--LPGACVKWWEKPS-
----------TLPQFSLPQIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKL---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLSESP---------------EKQQSVNL
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 736)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGARIPDSV-RDGLAYRGRVYL-ELITQIKSCQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLVHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIHDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 786)

HQWEKLLRELVEDCKRPLPCMTD-QPKATSLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQV--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHCGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDTAVYAET---YENQAKYKDQWGQQGLYRC
PSFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDIDINKSQVLEEVYENQGRDA
RGAWGPAAIPNTDVVSRAKAAS-----------------GVGGQARPPGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGA----LSRE-QETVSFLQL-GPA--EG-EEE
GWEYGAF-GSKFHLHPQPRSRFRRRCWRRRLAPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKYRAG--KEEDSKPWPWGLDR-Q--FRDPP
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQN---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLAMWDGGGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----TVLMPTEEAYSLPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPR--LSEKKHQ-----DFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPEDPEAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRATNLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPVFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPDEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2233)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPLPAQ

ENSGT00550000074414_4_Linker_9_10 (2233, 2301)

HAKQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
RLSVGAGETAL-----KLPG

PF16165 // ENSGT00550000074414_4_Domain_10 (2301, 2372)

SPAGRGQSEPNQYPTLHPPLRPHTSFMWLRSPVQHFCSVF
WKRYRFKLIAFVVILIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSNIFPELPAPED-

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 110)

LRVVVESASINPPLSTTPKAFVTVYFRDMMKRTRVEEGHDPIWNET-LIWHLWNQPLEN
DSFLKVILQDSVSKKKE-----------------RFIGLATVPLKRLAQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

RPKEVVFVRDL
ILLNHSMKPTNCTVTLQVAQ---------------IYDQ--------------DTEMTGN
EELLGSTVNEVTQKKLMVSGL-PMHRALASKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLLGNNIKPVVKINI
ADQQHLTRIKMGNNPFFNEIFFQNFHE-VPAKFFEENISIEVVDSAASRSKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQRNKTTSGVRGYLKV-TICALGVGDQALVDQKL---PYEQ
-NTRVQIFKSTEVPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQFFIYCAEDLHFGT-------------------HKSATP
VLEVELIGDKLRTKPQN-PSDSPIWNQILTFQIQLPCLSSYIKFRVMDCSKHKCQDEIGS
ASLCLSQISSTG

ENSGT00550000074414_4_Linker_3_4 (493, 735)

EEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKPPFRT-S-EEGTCIMDAV-QHGLAYRGRIFV-EIVTKIKSQQDSV-IKDL---SQEV
TQV---EMQYYRQKYGLCVIFLSCTMMPKFKDLIQFEVSMG-HYGNKTDPNYKPLVSTTQ
---YSPVIYDG--TTYHYVPWYNTKPVVAVTSNWEDVGFRMNCLNLLHITRDRLKTNLDI
LKSI-RNPRD-PAL

PF08165 // ENSGT00550000074414_4_Domain_4 (735, 787)

LQQWEKLLKELQEDCRRPLPCMTD-QPRANSLDRNKWQLRSQLLQQ
LAQMAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPVNMVGTAKEWLH-----------------RLNAVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VLIWLMSRQQRVAYARVPAHTVLFSPAGPLSSGKFCGKIQNLLLQYPEG---------EG
Q-DTFPASLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVKYSKNLKLLQQGSMVVYAET---YENQAKIKDDWGQQGLYHC
PNFSDVMGRKALPKTDFMAPPGWHWKDDWVVEPQRRLLLDIDINKSQVLEEVYENQLRNA
TGAWVPAAIPNMDVNGQPVEALENVKCPQGWHFKKNWIVELNHAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRVRFRNHKELGQELSQE-QETLSFLQMQDLS--EE-GKE
GWEYGTF-DSRFHLDPQPTSRFRRRCWHRQLAPNKDRGVASIFLLEGSLAVEQK------
-------------------------------DQ-P--RKEMEKMRSWQ--P-WKD-LRHT
--------PEDP-RIPTTPFIYY-ILNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1386)

QLFCYIYQARNLMYN-----QILTFQEP
FIQVVFLNHSLCTQTLRS---SAAPTWSQSIIFQHLLLFEDPKDTRENPPLVVLELWQHD
SRG-N

ENSGT00550000074414_4_Linker_6_7 (1386, 1594)

KILWGRSMWPPVVWLDLQD---------------WVFTPLRWHPLVRELGEEEGE
VLASCELILETQKL---------------K-ELHPPILSIPCKDGIYLLPKNIQPTMKMM
AIE---------------------------------------------------------
---------IMAWGLRNMTK-----VRYPQLLL

PF00168 // ENSGT00550000074414_4_Domain_7 (1594, 1665)

ECGGESLKTEPISNFQENPNFPTSTFF
F------TVFMPLEETHAQPLVVKVVDNQEYGQQIVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWSLN----
---------------YTTVKLPT--LSVKKPD-----TFLDFVYK--KFWFDSSKDEDVY
E--EEVDWWSKLF--WATGDAD---KSLNYNHKSYHTLKVYDCELEAVLTFKGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPDAPKPPRQFSAWPEIEDFPQMCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYY--PNTLDPIFGMMYELTCNIPLEKD
LEIQLFDFDLITADDEIGSTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2126)

LLSGFGARCGLSKSYCKSGP--FKWRDQMTPSY
LLYRYAKQKG-LPPPVFDLEGDSLYYNGETFKLQSFESAPPTYKHLGPKKERLALYILNT
QGLVPEHVETRTLHSNSQPGIDQGKIQMWVDIFPKMLGPPGPQVNISPRKPK--------
-RYQLRCIIWSTAEVDLVRETFSKE

PF00168 // ENSGT00550000074414_4_Domain_9 (2126, 2231)

KMSDIYV-KGWLFGLEEDTQKTDVHYHSLTGEATF
NWRFVFTMDYLTTERACVQSQKDYIWSLDPTSTKFPARLMIQIWDNDFFSPDDFLG--VL
ELDLSDMPLP

ENSGT00550000074414_4_Linker_9_10 (2231, 2279)

AQNIKQCSLKMMETDSKWPF-TPQKRISLFKKTNVTGWWPCQVLD-GD

PF16165 // ENSGT00550000074414_4_Domain_10 (2279, 2371)

KW
RLSGKVKMTLEMLSEREALIRPAGRGQSEPNQFPMLHPPERNDSFLLWYKSPIKNFCYAV
CKRYRSKIICLVVTLVIGFILLNFVYSAPSYFAMNWIKPQLRLSSPIKIV-NLIGTVNTS
NINSSILTMEG----------STYH----------ASH------VFPEAPAP---

MLQLVVESAKINPPLSP

PF00168 // ENSGT00550000074414_4_Domain_0 (18, 100)

PPRPCVSAYFRDVKKRTHEVEGNNPTWNET-LIWHLWDRPLQN
DSFLQIILRDLGSTKKD-----------------RFIGL

ENSGT00550000074414_4_Linker_0_1 (100, 218)

ATVMLQPLVKKPSEVLFVKDL
TLLNHLMMSTDCTVTLQVAL---------------MRNQDI--------------EKIGD
GDLLGLSTRETARQELMVPSY-TMPVALSTKPQHFQV

PF00168 // ENSGT00550000074414_4_Domain_1 (218, 264)

RVKVFEGRQLMGNNIKPVVKVVI
GGYQHNTRIKMGNNPFFNEIFFQ

ENSGT00550000074414_4_Linker_1_2 (264, 300)

NFHE-VPAKFFDETILI-----------------QT

PF08151 // ENSGT00550000074414_4_Domain_2 (300, 361)

D
IGFIYHSPGHTLMRKWLGLCQPNEPNNGVRGYLKV-TICVLGVGDQALVDQKP---PYAA

ENSGT00550000074414_4_Linker_2_3 (361, 382)

DDTTTKIFKSMVVPI-NMAYL

PF00168 // ENSGT00550000074414_4_Domain_3 (382, 481)

QFFIYCAEDLHLK-------------------KHHLVSP
MLEVELIGEKLKTNVLS-QTENPIWNQILTFHLQLPCLSSYIKFRILDCPKNSCRDEIGT

ENSGT00550000074414_4_Linker_3_4 (481, 738)

VSLFLNQISSTGAEIEGKQSPS-------------HHHPTPRPYSGFLPSFGPSFLILHG
GKKAPFRI-Q-EEGTNISSSV-KDGLAYRGRVFL-ELFTHVSSHQEFK-R-DL---SSQV
TSV---ERHQNRKKYGLCVIFLSCTMMPDFKDLIQFEVSIG-HYGNKMDLSYKPLVSTTQ
---CSPVIYDG--NIYHYVPWYNSKPVVAVTSFWEDSSFRMNCLNLLYFTRDRLKANLDT
LKSI-RNPRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 788)

WEKLLKELVEDCKHPLPCMTD-KLKATDLDKKRWQLRSRLLQE
LAQKAKQ

ENSGT00550000074414_4_Linker_4_5 (788, 832)

V----KPRNMVATVEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--TLPD
VMIWLMSKEQRVAYAQVPAHSILFSPTGALHSGRFCGKIQTLLLQYPEG---------EG
QKDTLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GNVTDSKDLQLLRQGEVVVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGHKALPKEDFHVPQGWHWQGKWTVEPQRRLLLNIDINKSQVLEEVYENQWRDT
AGAWVPAAIPNTDVNGDPVEARENFKCPQGWHVKENWVVELNHAVDDEGWEYGVGIEPSG
LPQVWNSVEKTYYSCRRRRWVRLRCRNHGK----LSLE-QETLSFLQLHHPS--QAEEEE
GWEYGTF-GSKFHLNPQPQSRFRRRCWRRRLALNRDKGIAPIFLLEGSMVTPLCNPTSQS
QGPAWVWQIVRQAKHPRASGRMSWAQSLDLKEQAR---KEENRRLTQGPDKTIRSYWRPA
--------PEDI-HPYDLPFIYC-IFNRPHYYQLF

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1390)

CYIYQARNIMSY-----QFQTSQVL
FIRLVFLNYSQCTQALRS---SAAPTWAQTLIFQHLLLYEDPEDTKASPPLVVLELWQQD
SQG-KETLW

ENSGT00550000074414_4_Linker_6_7 (1390, 1593)

GRSMWSPVVWLDVQN---------------RILPPLRWHPLVKLPGEEECE
ILVSCELILETESLK-----------------ERPPILSVPWKNGVYTLPKSIQPTLKKM
AVE---------------------------------------------------------
---------ILTWGLRNMKR-----VRSPQLL

PF00168 // ENSGT00550000074414_4_Domain_7 (1593, 1660)

VECLEESLQTEPIRDFQTNPNFTQSVLF
L------TLFMPMEDVYAPSLTLKVVDNQDFGRQTVVGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ANINSLQPYFCDPWADD----
---------------YVPPQLPMLSVK-----KYQ--KLLDYLYE--KFWLSPSKTQDEY
H--HEVDWWSKLF--WATGDV----KSLQYKYKDYHTLKVYDCELEAVPAFKGLQDFCET
FKLYQEEPKLDSPVV-GEFKGLFRVYPFPEDPKVPKPPRQFLVWREKEDFPQECLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1912)

RVYM
VRAINLQPQDSNGLCDPYVILKLGQTKMGNRDKYH--PNTLDPIFGIMFELSCIIPL---
---------LFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMTPSF
LLERHAKQKG-LPPPLFSPEEDTVFYNGKNFKLQSFEPTPPTLHYLGPKKERLALYLLHT
QGMVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIRPRKPRSKASEYSG
YRYELRCIIWKTAQVDLRRTL--TSGISDIYGGGGWMVGLEKDMQKTDIHYYSLTGESTF
NWRFIFSMDYLAAEHMCVQSQKEYIWSLDPTVIKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2216)

ARLIIQIWDNNVFSTDDFLGSGVL
ELDLFDMPLPARHASKCSIRMMETDSKWPYFLQYKHFSLFKKKTVTGWWPSQVLD-GGKW
RMSGKVKMTLEILSEKEALIRPAGRGQSEPNQYPTLHPPLRPNTMFL-LRSPITIFCRIF
WKRYHFKIIIAIIILFLALMLFNFIYSTPNYLAMSWIKPKLRLNAPIKISTNIINQPNLS
NVHSPILTSQH----------LNLNPTIDHELKHLQGPMNHLQDIFPELPAPRD-

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 110)

LRVVVESASINPPLSPTPKACVTVYFRDMKKRTRVEEGNGPIWNET-LIWHLWNQPLEN
DSFLKVILQDTVSKKKE-----------------RFIGLATVPLKRLAQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

RPKEVMFVRDL
ILLNHSMKPTNCTVTLQVAQ---------------IYDQ--------------DTEITGN
EELLGSTVNEVTQKKLMVSGF-PLHRALASKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLLGNNIKPVVKINI
AGQQHLTRIKMGNNPFFNEIFFQNFHE-VPAKFFEENISIEAVDSAASRSTAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQRNKTTSGVRGYLKV-TICALGVGDQALVDQKL---PYEQ
-NTQIQIFKSTEVPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQFFIYCAEDLHSST-------------------YKSATP
VLEVELIGDKLRTNPQS-QSDNPIWNQILTFQIQLPCLSSYIKFRVMDCSKHKCQDEIGS
ASLCLSQISSTG

ENSGT00550000074414_4_Linker_3_4 (493, 735)

EEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKPPFRT-S-EDGTCIMNAV-RDGLDYRGRIFV-EIVTKIKSQQDLI-IKDL---SQEV
TQV---EMQYYRQKYGLCVIFLSCTMMPKFKDLIQFEVSMG-HYGNKMDPNYKPLVSTTH
---HSPVIYDG--TTYHYVPWYNMKPVVAVTSNWEDVGFRMNCLNLLHITRDRLKTNLDI
LKSI-RNPRD-PAL

PF08165 // ENSGT00550000074414_4_Domain_4 (735, 786)

LQQWEKLLKELQEDCRHPLPCITD-QPRANSLDRNKWQLRNQLLQQ
IAQMA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KES----KPVNMVGTAEEWLH-----------------RLNAVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SFPD
VMIWLMSRQQRVAYARVPAHTVLFSPAGPLSSGKFCGKIQNLLLQYPEG---------EG
Q-DTFTAYLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVKYSKNLKLLQQGSMVVYAET---YENQAKIKDDWGQQGLYHC
PNFSDVMGHKALPKTDFKAPPGWHWKDDWVVEPQRRLLLDIDINKSQVLEEVYENQVRNA
TGAWVPAAIPNTDVNGQPTEALKKVKCPQGWHFKKNWIVELNHAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRVRFRNRKELGQELSQE-QETLSFLQMQDLS--EE-GKE
GWEYGTF-DSRFHLDPQPTSRFRRRCWHRQLAPNKDRGVASIFLLEGSLAVEQK------
-------------------------------DQ-P--RKEMEKTRSWQ--P-WKD-WRHT
--------PEDP-RIPTTPFIYS-IFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1386)

QLFCYIYQARNLMYN-----QILTFQEP
FIQVVFLNHSLCTQTLRS---SAAPTWSQTLIFQHLLLFEDPKDTRENPPLVVLELWQHD
SRG-N

ENSGT00550000074414_4_Linker_6_7 (1386, 1593)

KILWGRSMWPPVVWLGLQD---------------WVFTPLRWHPLVRELGEEEGE
ILASCELILETQKL---------------K-ELHPPILSVPCKNGIYLLPKNIEPSMKMM
AVE---------------------------------------------------------
---------IMAWGLRNMTK-----VRYPQLL

PF00168 // ENSGT00550000074414_4_Domain_7 (1593, 1665)

LECGEESLRTEPISNFQENPNFPTSTFF
F------TVFMPLEETHAQPLVVKVVDNQEYGQQIVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWSLN----
---------------YTTVKLPT--LSVKKPD-----TFLDFVYK--KFWFDSSKDEDDY
E-EEEVDWWSKLA--WATGDVD---KSLNYNHKSYHTLKVYDCELEAVLTFKGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPDAPKPPRQFSAWPEIEDFPQICL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYY--PNTLDPIFGTVYELTCNIPLEKD
LEIQLFDFDLITADDEIGSTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2126)

LLSGFGARCGLSKSYCKSGP--FKWRDQMTPSY
LLYRYAKQKG-LPPPVFDLEGDSIYYNGEKFKLQSFESAPPTYKHLGPKKERLALYILNT
QGLVPEHVETRTLHTNSQPGIDQGKIQMWVDIFPKMLGSPGPQVNISPRKPK--------
-RYQLRCIIWSTAEVDLVRETFSRE

PF00168 // ENSGT00550000074414_4_Domain_9 (2126, 2230)

KMSDIYV-KGWLFGLEKDTQKTDVHYHSLTGEATF
NWRFVFTMDYLTTERACVQSEKDYIWSLDPTPTKFPARLMIQIWDNDFFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2279)

PAQNIRQCSLKMMETDSKWPF-TPQKHISLFKKTNVTGWWPCQVLD-GD

PF16165 // ENSGT00550000074414_4_Domain_10 (2279, 2372)

KW
RLSGKVKMTLEMLSEREALIRPAGRGQSEPNQFPTLHPPERND-FLLWCRSPIKSFCYAV
CKRYRSKIICLVVTLVIGFVLFSFVYSAPSYLAMTWIKPQLRLYPPIKIV-NLIGTVNTS
SINSSIFTMEG----------SKLKPLKDHGPTYYASG------IFPEAPAP---

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 101)

LRLVVESATINPPLSPPPRPCVSVYFRDVKRRTHEAEGNNPTWNET-LIWFLWDRPLQN
DSFLQIILRDMAAVKKD-----------------RFIGLA

ENSGT00550000074414_4_Linker_0_1 (101, 217)

TILLHPLVKKPSEVLFVKDL
NLLNHLMLSTDHLADLPIPHPPTLPHLHPSLGTSLHNRQERGNSGDGLEVGWVVRALGGR
SDLLGPSAREAARQKLMVPGF-AMPPALSSKPQHFQ

PF00168 // ENSGT00550000074414_4_Domain_1 (217, 298)

VRVKVFEARQLMGNNIKPMVKVVI
GGYQHNTRIKMGNNPFFNEIFFQNFYE-VPAKLFDETILIQVMNSTLMRFNSEIGRF

ENSGT00550000074414_4_Linker_1_2 (298, 299)

Q

PF08151 // ENSGT00550000074414_4_Domain_2 (299, 360)

TD
IGFIYHSPGHTLMRKWLGLCQPNEPNNGVRGYLKV-TICVLGVGDQALVDQKL---PYG

ENSGT00550000074414_4_Linker_2_3 (360, 381)

A
DDSTTQIFKSTVVPI-NMAY

PF00168 // ENSGT00550000074414_4_Domain_3 (381, 482)

LQFFIYCAEDLHKKKML----LSQKSCNFLFAEKQHLVSP
MLEVELIGEKLKTNVLT-QTENPIWNQILTFQIQLPCLSSYIKFRVLDCPKNSCRDEIGT
VSLLLNQISSTGSEIEVLPLSH--------LALPPSPSLLAGTYSGFLPCFGPSFLTLRG
GKKAPFRI-Q-EEGTNISDSL-KDGLTYRGRVFL-ELFTHVTSHQDFK-RKDL---SSEV
TNI---ERHHHRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDGNRNIYHYVPWYNTKPVVAVTSHWEDVSFRMNCLNLLHFTRDRLKANLDT
LKSI-RNPRD-PALLPHWEKLLRELVEDCKHPLPCMTH-QPRATELDKKRWQLRSLLLQE
LAQKAKEV----KPRNMVATVEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 918)

PQM--SLPD
VMIWLMSKEQRVAYAQVPAHSILFSPTGALHSGRFCGKTQTLILQYPEG---------EG
QKDTLPAHLRVCMWLGN

ENSGT00550000074414_4_Linker_5_6 (918, 1294)

VTDSKDLQLLRQGEVVVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGHKALPKEDFQAPQGWHWQGQWTVEPQRRLLLDVDINKSQVLEEVYENQCRSS
TGAWVRAAVPNTDVNGEPVEARENVKCPQGWHIKENWIVELNHAVDSEGWEYGVGIEPSG
QPRVWNSVEKTYYSCRRRRWVRLRCRNHAG----ERATWAGTPTPRAMHHPS--PAKEEE
GWEYGTF-GSKFHLNPQPQSRFRRRCWHRRMAPNKDKGIAPIFLLEGSLGMD--------
-----------------------------LKEQAW---KEENKRLTQAPDKTTRSSWRPA
--------PEDT-QLHDLPFIYC-IFSKPHYYQ

PF00168 // ENSGT00550000074414_4_Domain_6 (1294, 1375)

LFCYIYQARNLMSS-----QIHTFRVP
FIRLVFLNHSQCTQTLKS---SAAPTWAQTLIFQHLLLYESPEDTKASPPLVVLELWQQD
SQG-KESLWARSMWSPVVWLDVQK---------------RTLPPLRWHPLVKLLGEKEGE
ILVSCELILETESVK-----------------EKPPIFSVPWKNGVYTLPKSIQPTLKKM
AVE---------------------------------------------------------
---------ILVWGLRNMKQ-----VRSPQLLVECWEESLQTEPIKDFQTNPNFTQSVLF
L------TLFMPTEAAYATPLTLKVVDNQDFGQQTVVGQANIHSLQPYFCDPWAED----
---------------YVPPQLPSTALS-----PCPFPGLTFKLAF--KAQVMQAQLQDEY
E--HEVDWWSKLF--WATGDVKGDVKSPRYKYKDHHTLKVYDCELEAVPAFEGLQDFCQT
FKLYQEEPKLDSPVV-GEFKGLFRVYPFPEDPKAPKPPRQFLVWREKEDFPQECL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYM
VRAINLQPQDSNGLCDPYVILKLGQTTMGNRDKYH--PNTLNPIFGIMFELSCTIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCYSGP--FRWRDQMTPSF
LLERHAKQKG-LPPPLFSPEEDTVFYNGKKFKLQSFEPTPPPVHYLGPKKERLALYLLHT
QGLVPEHVETRTLYSNSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIRPRKPK--------
-RYELRCIIWETAQVDLRRNV--TAEMSDIYV-KGWLVGLEKDMQKTDIHYHSLTGESNF
NWRFIFTMDYLAAEHMCVQSQKDYIWSLDPTVMKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2219)

ARLIIQVWDNNIFSTDDFLGSGVL
ELDLFDMPLPARHANLCSIRMMDTDSKWPYFLQYKHFSLFKKKTVTGWWPSQVLD-GGKW
RMSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPNTMFM-LRSPVTIFCRIF
WKRYHFKIIIGAIIFIIALMLFNFIYSTPNYLAMSWIKPEL-------------------
-------------------------------------------------------

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-----------------MKN-----VRSPYLLVECGDKSQRTEPIKNFQTNPNFPQSALF
F------T-FMPTEEAYSLPLTVKVVDTRDFGQQTVVGQANVDFLQPYFCDPWADN----
---------------YVPPKIPT--LSIKKYH-----ELLDYLYK--KLWLNYHKAEDEH
D--YDVDWWSKLS--WTMRDTH---KSLEYKDKDYHTLKVYDCELEAVPEFKGLQDFCQT
FKLYKEKPVLDSPVV-GEFKGLFRIYPFPEDPKATKPPRQFLAWPEREGFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYV
VRAFSLQPQDYNGLCDPYVIVKVGQKQLGNRDAYQ--PNTLDPIFGKMFELSCNIPLEKD
LEIHLYDFDLLSPDDKIGTT

ENSGT00550000074414_4_Linker_8_9 (1941, 2105)

VIDLENRLLSGFGARCGLSKSYCQSGP--FMWRDQIPPSY
LLERHARLKG-LPPPLFNSEDNSVFYNGKQFKLQSFEPKPPTAEDLGPEKERLALYLLHT
QGLVPEHLETRTLYSDSQPGIDQGKVQMWVDIFPKRLGPPGPPVNISPRKPK--------
-RYE

PF00168 // ENSGT00550000074414_4_Domain_9 (2105, 2221)

LRCIIWQVSNVDLQNSSYTGEKTSDIYV-KGWLLGLEKDTQKTDIHYYSTTGKGYF
NWRFVFTMDYLAAEQMCIQSQKEYIWSLDPTSLKFPPRLVIQVWDNDLLSSDDFLG--VL
ELDLSDMPFPARYAKNCSMRIMETESKWPHFHQHKHISLFKKKIVTGWWPCQILD-NGKW
RLSGKVNMTLEILTEEEALLKPAGRGQSEPNQYPTLQAPIS----LKWMLLPLQTFVHYI
WKHNRYRILTVFVILSLLYLLFNFIYATPNYLAMSLIKPGVRVQTPNEVSSNVITSLITN
T-SSSVLGTNL-----------KLQP--AITDHEVQGPMNLLRDLFPGLSIPD--

MLRLV

PF00168 // ENSGT00550000074414_4_Domain_0 (6, 109)

VESAKIEPPLSPPPRPCLTVYFRDVKKRTRVTEGNHPTWNET-LIWHLWSRPLEN
DSFLQLILRDMGSKKKE-----------------RFIGLATVLLKPLV

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KKPREVLFVKDL
NLLNHSMMPTDCTVTLQVAH---------------VIHW--------------DTQKTGG
EDPLGMTTWEAAQQKLLVPSSAGMHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 305)

QVQVKVFEARQLMGNNIHPLVKVTI
AGQQHHTRIKMGNNPFFNEIFFQNFHE-VPAKFFDEIILVQVLNSSVMRSKAEIGRFQVS
P--SSASPGHTLLRKWLGLCQPNVPGSGVRGYLKV-TICALGVGDQALVDQKL---LYRD
-DTDIEVFKSTAVPM-ATA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 487)

YLQLFIYCAEDLLMHK-------------------R--ASP
VLEVELIGEKLRTKVQH-QTDNPIWNQILTFQIQCS----------LRSATSNCQDEIGT
ASLSLS

ENSGT00550000074414_4_Linker_3_4 (487, 738)

HISSTGEEIEG-------------------------LYSGFLPCFGPSFLPLHG
GPQAPSRI-Q-EE--STPGAP-GDGLSYRGRVLL-ELITQIKSHQDSM-IKDL---SQEV
ARI---EKHQNRQKYGLCVVFLSCTMMPNFKDFIQFEVSIG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDG--NIYHYIPWYNTKPVVAVTSSWEDVSFRMHGLNLLQFARDRLKANLDT
LKSI-RNPRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 787)

WEKLRRDFVKDCRRPLPCMTG-QPKATNLDRKRWQLRSLLLQE
LAQRAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRDMVATVEGWLR-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQV--SLPD
VMIWLIAEEQRVAFARVPAHTVIFSPEGPLYSGKFCGKIQTLLLQYPEG---------EG
QQDGPLAHLRVCMWF

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNITDSKDLQLLRQGDMVVYAET---YENQAKYKDQWGQQGLYHC
PHFSDVMGHKALPKSEFKEPPGWHWQDRWIVEPQRRFLLDIDVNKSQVLEEVYENQERNV
TGTWVPSATPNTDVNGQPVKARDNVTCPQGWHFKKKWAVELNRAVDSEGWEYGVGIPPSG
LPRVWTSVEKNYHSRRRRHWVRMRFRNHG----ELGRE-EQTVSFLQMQGLA---REGEE
GWEYGSL-GSTFHLDPQPQSRFRRRCWHRRLAPNKNTEVAPIFLLEGSLVN---------
------------------------------------------------P---VRDSWQPA
--------REDQ-QLPNMPFIYC-TLDKPCYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLIPN-----QILVFQEP
FVRVVFLNYSQCTQHLPS---SSAPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1574)

QHLLLHESPQDTQESPPLVVLELWQRD
AQG-KESLWGRSMWPPVVWLDLRH---------------WMLPPLRWHPLVKELREEAGE
ILAACELILETEKL----------------REKHLPLLSVPWKDGIYMLPKSIQPTMRKT
AIE---------------------------------------------------------
---------ILAW

PF00168 // ENSGT00550000074414_4_Domain_7 (1574, 1664)

GLRNMKQ-----ARHPQLLVECGGESLRTEPIRDFPTNPNFPESALI
L------TVFMPKEEAYVQPLQLKVLDNQDFGRQTVVGHASVD

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLRPYFCDPWAD-----
---------------VRAPVPAL--GW--------------FFYQ--KFWFKSS--KDEY
E--HDADWWSKLF--WATGDD----KSPKYKYQDYHTLKVYNCELEAVPAFQGLQDFCQT
FKLYQEEPKVDSPVV-GEFKGLFRIYPFPENPEAPKPPRQFLAWPEREDLPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGSTKLGSRDAYK--PNTVDPIFGTMFELTCTIPLEKD
LQIQLLDFDLFSLDDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2128)

LLSGFGARCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPRPVFDPEGDSVLYRGKKFNLQNFEPKAPTAPDLGPKKERLALYILHT
QGLVPEHVETRTLYSDSLPGMDQGKVQMWVDIFPQKLGPPGPPVKISTRKPK--------
-RYELRCIVWKTAHVDLVDEALSREKM

PF00168 // ENSGT00550000074414_4_Domain_9 (2128, 2232)

SDIYV-KGWLFGLEKNMQQTDVHYHSLTGEAIF
NWRFIFTMDYLAAERMCIESQKDYVWSLDPTSTKFPARLIIQIWDNDTFTSDDFLG--VL
ELDLSDMPRPA

ENSGT00550000074414_4_Linker_9_10 (2232, 2281)

RHAKQCSLQMLDSEPKWPYFVPHERFSLFKKKTVTGWWPCQVQE-GDKQ

PF16165 // ENSGT00550000074414_4_Domain_10 (2281, 2372)

RLSGKVKMTLEVLLEKEALARPAGRGQSEPNQYPTLYPPLRASSSFMWLRSP-RYLCFGL
CRRYRCKILSFLALLVVAFMLFKFIYSAPNYLALNLIRPGLRMQPPIKIY-NLITWPTVS
NVPSQRLGDIF----------PELLAP----------------------------

------ESARIEPPLSPP

PF00168 // ENSGT00550000074414_4_Domain_0 (19, 109)

PRPCLTVYFRDIKKRTRVVEGNDPTWNET-LIWHLWSRPLEN
DSFLQVILRDMGSKKKE-----------------RFIGLATVLLKPLV

ENSGT00550000074414_4_Linker_0_1 (109, 216)

KKPREVLFVKDL
ILLNHSMMPTDCTVSLQVAH---------------VMPR--------------DTEKEGG
GDPLGMTTRELAQGKLMVPGSAGLHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 301)

QVRVKVFEARQLMGNNIRPVVKVTI
AGQQYHTRIKMGNSPFFNEIFFQNFYE-VPAKFFDEIILVQVLNSSVMRSKAEIGRFQTD
IGFVYHSPGHTLLRKWLGLCQPNAPSSGVRGYLKV-TICALGVGDQALVDQKL---PYRA
-DMDIEVFKSTAVPT-TMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQLFIYCAEDLLLGR-------------------NQSVSL
VLEVELIGEKLRTNVRP-QTDNPIWNQILTFQIQLPCLSSYIKFRALDCSRSDCWAEIGT
ASLSLGHISSSG

ENSGT00550000074414_4_Linker_3_4 (493, 738)

EEIGG-------------------------HFLGFLPCFGPSFLPLYG
GPKAPLRI-Q-EEGTSVPDAI-RDGLSYRGRVLL-ELITQIKSHQHTM-IKDL---SQEV
ARI---EKHQNRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSSWEDVSFRMHCLNLLQFARDRLKANLDV
LKSM-RNLRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 786)

WEKLRRELVEDCRRPLPCMAD-QPKATNLDRKRWQLRSLLLQD
LARKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KEA----KTRDMVATVEGWLH-----------------CLNSVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--SLPD
VMIWLMAKEQRVAFAQVPAHTILFSRAGPLHCGRFCGKIQTLLLQYPEG---------EG
QQDMLPAHLRVCMWF

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGNMVVYLET---YENQAKFKDQWGQQGLYHC
PNFSDVTGHKALPKSKFKVPSGWHWQDSWKVEPQRRLLLDIDINKSQVLEEVYENQERNF
SGSWVSSAIPNTDVNGQPMEARDTVRCPQGWHFKKNWAVELNHSVDSEGWEYGVGIPPSG
LPRLWTSVEKNYHSCRRRRWVRMRFRDHG----ELGGE-EQTVSFLQMQGLV---SEGEE
GWEYGSF-GSKFHLDPQPQSRFRRRCWHRRLAPNKNTSVAPIFLLEGSLATDLKQ-----
-----------------------------------NPKKEENRALPWAQ---FRDAWKPA
--------QEDP-RLPSMPFIYC-TLDKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSN-----QVLAFQGP
FVRAVFLNYSQCTQRLPS---SVAPIWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1574)

QHLLLHESPQDTRESPPLVVLELWQCD
ALG-KESLWGRSMWPPVVWLDPQD---------------WMLPPLRWHPLVKERGEEEGE
ILASCELILETEKL----------------REKHLPLLSIPWKDGVYTLPKSIQPTVRKT
AIE---------------------------------------------------------
---------ILAW

PF00168 // ENSGT00550000074414_4_Domain_7 (1574, 1664)

GLRNMKQ-----ARHPQLLVEFGGESLRTEPIKDFPTNPNFPESVLL
L------MVFMPKEEVYSEPLVLKVLDNQDFGRQIVLGQASVD

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWARD----
---------------YLSGLLTS--PYLPPAF-----QVLGFLYE--KFWFKSSRPEDEY
E--HEVDWWSKLF--WATGDD----KSLQDKYQDYHTLKVYDCELEAVPDFQGLEDFCQT
FKLYQEQPKVDSPVV-GEFKGLFRIYPFPENPEAPKPPRQFLTWPEREDFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVVLKLGSMKLGSRDAYK--PNTVDPIFGMMFQLTCTIPLEKD
LQIQLYDFDLFSFDDEIGSTFIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPVFDPDGDSVFYRGKKFKLQSFESKAPTMPGLGPKKERLALHILHT
QGLVPEHVETRTLYSESQPGIDQGKVQMWVDIFPQKLGPPGPPVKISTRKPK--------
-RYELRCIVWKTTQVDLVDEALSREKMSDIYI-KGWLFGLEKNMQKTDIHYHSLSGEATF
NWRFIFTMDYLAAEHMCVESQKDYI

PF00168 // ENSGT00550000074414_4_Domain_9 (2186, 2232)

WSLDPTSTKFPARLIIQIWDNDIFSSDDFLG--VL
ELDLSDMPRPA

ENSGT00550000074414_4_Linker_9_10 (2232, 2278)

RHAKQCSLRMLDAKPKWPF-LPHEHFSLFKKKTVTGWWPCQVQD-G

PF16165 // ENSGT00550000074414_4_Domain_10 (2278, 2372)

DKW
RLSGKVKMTLEVLSEKEASARPAGQGQSEPNQYPTLHPPLRAGSSFMWLRSPVRHLCLSL
CRRYRCKILSFSVLLVIAFMLFKFIYSAPNYLAMSWIHPAIRMEPPIKIY-NLITSATAS
TASPAPLATQA----------PSLEPVTDHQLPILQAP-----------------

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---------------------------------------------------------DDF
E--HEVDWWSKLF--WAIRD-D---KSLKYKYKDYFTIKVYDCELEAVPDFQGLQDFCQT
FKLYQEQPKVDSPVV-GEFKGLFRIYPFPENPEAPKPPRQFLVWPNREDFPQQCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYI
VRAINLQPQDYNGLCDPYVILKMGQTKLGNRDTYR--PNTLDPIFGMLFELTCNIPLEKD
LEIQILDFDLVSADDEIGST

ENSGT00550000074414_4_Linker_8_9 (1941, 2105)

VIDLENRLLSGFHASCGLAKTYCQTGP--FRWRDQMSPSH
MLERFAKQKG-LPPPLYSLEEDSVLYNGEKFKLQSFEPKPPNVPGLGPKKERLALYILNT
QGLVPEHVETRTLYSNSQPGIDQGKVQLWVDIFPKNLGPPGPHVNISPRKPK--------
-RYE

PF00168 // ENSGT00550000074414_4_Domain_9 (2105, 2221)

LRCIIWKTADVDLVDVSLTSEKMSDIYI-KGWLFGMEKDTQKTDIHYHSLNGEGNF
NWRFIFTMDYLAAECMCVQSQKDYIWSLDPTSMKFPARLIIQVWDNDTFTSDDFLG--VL
ELDLSDMPYPARSAKQCSLRMMEQDPKWPQFLQHKHFSLFKKTTVTGWWPCQVLE-GDKW
RQSGKVKMTLEILSQKEALIKPAGRGQSEPNQYPTLHPP--------WLRSPIQNFCVVF
WKRYRYKIIALSILVSIALLLFHFIYSTPNYLAMNWIKPEMRLYPPIKIV-NIIGSSNTS
NDSSSNLITEK----------PSPETTPEQQWELVQEPRNQMYDIFPELPTPGS-

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDTGSQKEES-----------------FIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSKVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHR--------------DIEKTGA
EDLLGITAREAARQKLLVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKQ---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 494)

YLQFFIYCAEDLHLSESP---------------ENQQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFQIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISSTGE

ENSGT00550000074414_4_Linker_3_4 (494, 737)

EIEG-------------------------AYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGAV-SLSH-QDGLAYRGRVFL-ELITQIKSCQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNIKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLC

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIQTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDTDINKSQVLEEVYENQGRDI
RGAWGPAAIPNTDVNGQPTEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLHL-GPA--EG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLMKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLATWDGDGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEAAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPS--------------TFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFMWLRSPAQHFCSVF
WKRYRFKLIAFMVISILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSNIFPELPAPED-

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-----------------MKE-----VRAPQLLVECWEETLQTEPIKDFPSNPNFAQSVLF
L-------TFMPTEAAYALPLVLKVVDDRDFGQQAVVGQANIDSLQPYFCDPWALD----
---------------YVPPRLPK--LCVNKHQ-------LLYLSE--KFWFKFSKTEDEY
E--HE-DWWSKLF--WATGDD----KSPKHKDRDYHT--VYDCELEAVPAFQGLQDFCQT
FKLYQESPKVDSPVV-GEFKGLFRVYPLPENPEAPKPPRQLSVLPKKEDFPQQCV

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1941)

VRVYV
VRAINLQPQDYNGLCDPYVIL-LGETKLGSRDKYQ--ANTLDPIFGMMFELSCTIPLEKD
LEVQLYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSQSYCQSGP--FRWRDQVLPSF
LLEHHAKRKG-LPPPLFNPNGDSVFYNGRKFKLQRFEPKPPSARYFGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIMPRKPK--------
-RYELRCIIWETAQVDLKNITLSNEMISDIYV-KGWLFGLEKDMQKTDVHYSSLTGEGSF
NWRFIFTLDYLAAEQVCVLSQKDYIWSLDPTVMKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2221)

ARLIIQVWDNDFFSMDDFLG--VL
ELDLSDMPLPARHAKLCSARMMDAEPKWPYFLRHEHFSLFKKKTVTGWWPCQVLE-DGKW
RLSGKVKMTLEILTEKEALIRPAGRGQSEPNQYPTLHPPLRTTTLLSWLQSPIKNILRIF
WKRYRFKITVVSIILIMGLILFNFMYSAPNYLAMDWVKPKLRLNSPITIVNNIINSLNAS
HNNSSVLVTQHLNR------EPTIEPTTNHELKLLQGPINHLQDIFPELPAPRG-

MLRLIMQSAKISPPLSP

PF00168 // ENSGT00550000074414_4_Domain_0 (18, 100)

PPRPCVSVYFRDVKRTTREVEGNHPVWNET-LIWHLWNHPLQK
DSFLQITLRDMGSVKKE-----------------RFIGM

ENSGT00550000074414_4_Linker_0_1 (100, 218)

ATVLLKPLVKKPRKILFVNDL
TLLNHSMMPTECTVTLQAAL---------------MTYK--------------DIEKIGD
EDLLAITAQEVAKQKLMFPSA-TVHKALSPKPQHFQV

PF00168 // ENSGT00550000074414_4_Domain_1 (218, 264)

RVQVFEARQLMGNDIKPVVKVVI
GGHQHHSRIKIGNNPFFNEIFFQ

ENSGT00550000074414_4_Linker_1_2 (264, 300)

NFYE-APMKFFDEIILI-----------------QT

PF08151 // ENSGT00550000074414_4_Domain_2 (300, 357)

D
IGFIYNCPGHTLLRKWLGLCQPNERNSGVRGYLKV-TICALGVGDQAPVDQKL---

ENSGT00550000074414_4_Linker_2_3 (357, 382)

IYRV
DDTDTRIFKSSVVPI-SIAYL

PF00168 // ENSGT00550000074414_4_Domain_3 (382, 481)

QFFIYCAEDLHLKK-------------------HYSVSP
MLEVELIGEKLKTHVQT-QTESPIWNQILTFRIQLPCLSSYIKFRVLDCPRNRCNDEIGT

ENSGT00550000074414_4_Linker_3_4 (481, 738)

VSLSLNQISSTGAEIEGKQA--P-------------CALPPGMYSGFLPCFGPSFLTLRG
GKKAPFRM-K-EEDPNIPNIV-KDGLAYRGRVFL-ELITHIKSRQEAK-MKDL---SLDV
ISI---EKHQNRQKYGLCVIFLSCTMMPDFKDLIQFEVSIG-HYGNKMDLSYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSFWEDVGFRMNCLNLLQFTRDRLKANLDT
LKSM-RNPRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 786)

WEKLLRELVEDCKRPLPCMTS-QPKATDLDKNRWKLHRLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----PPRDMVATAEGWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--NLPD
VMIWLMAREQRAAYAQVPAHSILFSPHGARHSGRFCGKTQTLFLQYPEG---------EG
EKDTLPAQLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GNVTDSRDLELLRQGEVVVYAET---YENQAKFKDQWGQQFLQHR
PNFSDVTGHKALPKEDFREPPGWHWAGPWTVEPQRRLLLDTDINKSQVLEEVYENQRRDA
VGAWVPAAIPNTDVNGEPVEAREIVKCPQGWHVKQTWAVELNHAVDNEGWEYGVGIPPSG
LPQVWNSVEKTYYSRRRRRWARVRYRDHGQ----LSHE-QETLSFLQLHHPG--LAEDEA
GWEYGVF-GSKFHLNPEPQSRFRRRCWHRRLAPNKVKGIAPIFLLEGSLDMLGLW--L-G
RRVTWAWAGGDKKGTQEPQG-LSWAQSTDMKEQAR--RADMVSS-TRRLDR-IMSSRRAP
--------PGIT-QTPSLPFIYC-VFNKPHYYQLF

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1385)

CYIYQARNLMSS-----HVQTFQGP
FIRLVFLNHSQCTQTLKS---STAPTWAQTLIFQHLLLYENPQDTRESPPCVVLELWQRD
PQG-

ENSGT00550000074414_4_Linker_6_7 (1385, 1594)

NETLWGRSIWHPVVWLDAQD---------------RILPPMRWHPLVKGLEDEEGE
ILASCELILETESL---------------R--QQLPMLSVPWKNGIYILPKSIQPTLRKM
AIE---------------------------------------------------------
---------MLVWGLRNMKQ-----VRSPQLLV

PF00168 // ENSGT00550000074414_4_Domain_7 (1594, 1660)

ECWEESLQTEPIRDFQTNPNFAQSALL
L------TLYMPTEETFALPLVLKVVDNQDFGQETVVGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ANVHSLQPYFCDPWAED----
---------------YVPPRPPT--LSVKKYQ-----ELLGYLYE--KFWFKSSKAEDEY
D--QEVDWWSKLF--WATGDAP---QTLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEWPRLDSPVV-GEFKGQFRVYPFPENPEAPKPPRQFPLWPKKEDFPQQCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYI
VRAFHLQPQDFNGLCDPYVILKLGQTMLGNRDKYQ--PNTLDPIFGVMFELSCTIPLEKD
LEIQLYDFDLFSPDDMIGTTVIDLEDRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSL
LLEHHAKRKG-LPPPLFSPEGDSVYYNGKKFELQSFELKPPRARFLGSKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNIGPRKPKSKASDNGG
CRYELRCVIWKTTLVDPKEKSLSYDRINDIYV-KGWLFGLEKDMQKTDVHYRSLTGEGIF
NWRFIFTLDYLAAEHVCVLSEKDYIWSLDPTVTKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2220)

ARLIIQVWDNNIISTDDFIG--VL
ELDLSDMPLPAPHARLCSVRMLEADPKWPHFLQHKHSSLFKMKNVAGWWPCQVLD-GGKW
RLSGKVKMTLEILTEKEALIKAAGRGQSEPNQYPTLHPPLRTHTLFMWFRSPIGKFIRVF
WRRYRFRIIAAAIILLIGLLLFNFIYSAPNYLAMSWIKPELRLNAPIQIYANIINAPNAS
STNSSNLTTPQ----------QSLKPTTALRLKHLQGHVTHLRDILPALPAP---

MLRLVVESARIE

PF00168 // ENSGT00550000074414_4_Domain_0 (13, 54)

PPLSPPPRPCLTVYFRDIKKRTRVVEGNDPTWNET-LIWHL

ENSGT00550000074414_4_Linker_0_1 (54, 216)

WSPGDGG
L-----------------------------------------------------------
----TTSLPLQSTVNLQVAH---------------VTHW--------------DSEKTGG
GDPLGITTKEAVQQKFPIPGSTGMPRILSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLMGNNIQPVVKVTI
AGQQYHTRIKMGNNPFFNEIFFQNFYE-VPAKFFEEIII--VLNSSAMRSKAEIGRFQTD
VGFVYHSPGHTLLRKWLGLCLLNEPGSGVRGYVKV-TICVLGVGDQALVDQKL---LYGA
-DTDVEVIKSAAVQT-TMAYLQLFIYCAEDLRGAG-------------------QEVP--
-------QILK

PF00168 // ENSGT00550000074414_4_Domain_3 (432, 487)

GTKVRH-QTDNPIWNQVLTFQIQLPCLSTT-------DKRNDCLEEIGA
ASLSLS

ENSGT00550000074414_4_Linker_3_4 (487, 737)

HISSTGEEIEG-------------------------LYSGFLPCFGPCFLPLHG
GPQAPMRI-Q-EEAASIPDPV-GDGLSYRGRVLL-ELTTQIKSHQGST-IKDL---SHEV
ARI---EKHQNRLKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLNYKPLVSATQ
---YSPVIYDG--NIYYYIPWYNTKPVVAVTSNWEDVSLRMRCLNLLQFARDRLKANLDT
LRSM-RNPRD-PALLP

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLQELIEDCRRPLPCMTD-QPRATDLDRKRWELRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRDMVPTVEGWLR-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQR--SLPD
VMIWLIAKEQRVAFARVPAHTVLFSPAGPLHSGRFCGKIQTLLLQYPEG---------EG
QQNAPPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GDVTDSRDLQLLRHGDLVVYAET---YENQAKYKDQWGQQGLYQC
PNFSDVMGHKALPKSEFKAPPGWHWQDSWRVEPQRRFLLDIDINKSQVLEEVYENQDRDS
TGTWVPSATPNTDVNGHSVPARDTVTCPKGWHFKKNWAVELNHAVDSEGWEYGVGIPPSG
LPRVWTSVEKNYHSSRRRRWVRMRFRNHND---ELSLE-EQTVSFLQMQGLA---DAGEE
GWEYGSL-GSRFHLDPQPQSRFRRRCWHRRLALNIDTGVAPIFLLEGSLAMDLKQ-----
-----------------------------------KRKKDESKARAW----------TQA
--------QGDQ-RLPTMPFIYY-TLHKPHCY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLISK-----QIVAFQGP
FVRVVFLNYSQCTQHRPS---SSAPTWAQTLIFQHLLLHESPQDTQKSPPLVVLELWQRD
AQG-KESLWGRSMWPPVVWLDLRD---------------WMLPPLRWHPLVKELGEEECE
IFASCELILETEKL----------------KEKHLPLLSIPWKDGAYTLPKSIQPTMRKT
AIE---------------------------------------------------------
---------VLAWGLRNLKR-----ARYPQLLVECGGESLQTEPIEDFLANPNFPESALL
L------TVYMPMEEAYTQSLVMKVLDNQNFGQQTVVGQASVDFLQPYFCDPWAPD----
---------------YLPG------------L-----QVIGFLYD--KFWFKPGKAEYEY
E--YEVDWWSKLF--WATGDD----KSLKYKYQSYHTLKLYDCELEAVPAFQGLQDFCQT
FKLYQEQPKADSPVV-GEFKGLFRIYPLPENPEAPQPPRQFLAWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYM
VRAINLQPQDYNGLCDPYVILKLGSTKLGSRDKYK--PNTVDPIFGTMFELTCTIPLEKD
LHIQLYDFDLFSHDDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2170)

LLSGFGARCGLSKSYCQSGP--FTWRDQMPPSF
LLERYAKRKG-LSPPVFDPEGDSVLYSGERFTLQNFESEAPTVPGLGPKKERLALYILHT
QGLVPEHVETRTLYSDSQPGVDQGKVQMWVDIFPQKLGPPGPPVIISTREPK--------
-RYELRCIIWKTAQVDLVDEALSREKMSDIYV-KGWLFSLEKDMQKTDIHYHSLTGEAIF
NWRFIFTMD

PF00168 // ENSGT00550000074414_4_Domain_9 (2170, 2228)

YMAAEHVCIESHKDYIWSLDPTSTKFPARLIIQIWDNDTLSSDDFLG--VL
ELDLSDM

ENSGT00550000074414_4_Linker_9_10 (2228, 2277)

PYPARHAKQCSLHMLDTEPKWPHSLPHERISLFKKKIVTGWWPCQVQE-

PF16165 // ENSGT00550000074414_4_Domain_10 (2277, 2372)

GDKW
RLSGKVKMTLEVLSEKEALTRPAGQGQSEPNQYPTLHPPLRASSAFMWLRSPIRTLCLGL
CKRYRCKILTFLLLLGIGFLLFKFIYSAPNYLAMNWIRPGLRMQTPIKIY-NLLTSPTVS
NASPSPAATQA----------PSLQPSTNHQLPLLQAPNQHLDDIYPELPTP---

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDTGSQKEES-----------------FIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSKVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHR--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKQ---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLSESP---------------EKQQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGARIPDSV-RDGLAYRGRVFL-ELVTQIKSCQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNIKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLC

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIQTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDTDINKSQVLEEVYENQGRDI
RGAWGPAAIPNTDVNGQPTEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLQL-GPA--EG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLMKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLATWDGDGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YAHPKLPR--LSGKKHQ-----DFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSASQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFIWLQSPVQHFCSVF
WKRYRFKLIAFMVISILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTTDHEWKLHPGPTNHLSNIFPELPAPED-

MLRLVVESAKIDPPLTPP

PF00168 // ENSGT00550000074414_4_Domain_0 (19, 112)

PRTCVYVNFRDTEKRTHVVEGNNPVWNET-LIWYLWKRPLEN
KSFLQVTLQDLGSENKE-----------------RFIGLATVVLKPLVKRP

ENSGT00550000074414_4_Linker_0_1 (112, 216)

RKVHFVKNL
TLLNHSLTQTDCTITLQVAH---------------MTTR--------------DIEKTGD
DDRLGITTREAAKQKMPLPTS-AVQRALCTKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 262)

QVRVRVFEGRQLMGNNIKPLVKLSI
GGQQQQTRIKMGNNPFFNELF

ENSGT00550000074414_4_Linker_1_2 (262, 321)

FQNFYE-IPTKFFDETILI-----------------QTD
IGFVYYSPDHSLLRKWLGLC

PF08151 // ENSGT00550000074414_4_Domain_2 (321, 350)

QPDKPESGVTGYLKV-TISVLGVGDQVPV

ENSGT00550000074414_4_Linker_2_3 (350, 380)

DQKL---PYRV
DDTEVQIFKSTAVPI-HMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 490)

YLQFFIYCAEDLHFKK-------------------HQSVNP
MLEVELIGEKLKTHVPA-PTDNPIWNQILTFQIQVPCLSSYIKFRVLDCSRNDCRDEIGS
ASLFLNQIS

ENSGT00550000074414_4_Linker_3_4 (490, 736)

SAGEQIPGKQS--P-------------GPYLPRVSSGFLPCFGPSFLTLHG
GKKAPFRI-S-EEGACISESV-KDGLAYRGRVFL-ELITQIKSKQDNW-IKDL---SHEV
TMI---EKHQNRHKYGLCVIFLSCTMMPNFNDLIQFEVSIG-HYGNKLDLNYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRVNCLNLLHFTRDRLKANLDT
LKSM-RNPKD-PALL

PF08165 // ENSGT00550000074414_4_Domain_4 (736, 786)

HQWEKLLRELVEDCKRPLPCMTD-QPAATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KHA----KPRDMVATVEGWLY-----------------HLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQI--SLPD
VMIWLMAKEQRVAYARVPAHSVLFSQAGARYSGRFCGKIQTLLLQYPEG---------EG
PKDTLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDIVVYAET---YENQAKYQDQWGMQGLSHC
PNFSDVMGNKALPKKDFQPPPGWHWWDKWRVEPQRRLLLDIDINKSQVLEEVYENQTRDA
RGAWVPAAIPNTDVNGQAVEARDNVKCPQGWHFKKNWIVELNRAVD--SWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRLRFRNHGE----LSLE-QETLSFLEQHNLA--KG-EEE
GWEYGTF-RSKFDLNPQPQSRFRRRCWHRRLAPDKDKGVAPIFLLEGSLVKR--------
-QP--AWE-GCSRSTQEPQRRLSWAQAMDLKQHAK--KEEEDKSWRSSM--------RRI
--------PEDT-RPPNMPFIYC-IFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSN-----QILTFEEP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1588)

QHLPLYENPQDTKESPPLVVLELWQPK
SSG-K-NLWGRSMWPPVVWLDLHN---------------RTLPPMRWHPIVNELGAEDGE
ILASCELILETEVL---------------GQEKQRPILSVPWKNGVYTLPKGIQPTLKKM
AIE---------------------------------------------------------
---------ILAWGLRNMK------VN

PF00168 // ENSGT00550000074414_4_Domain_7 (1588, 1665)

SPQLLVEFGEESLRTEPISDFQTNPNFPESILL
L------IVYMPTEEAYAQPLVVKVVDVRIFGQQTVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAKD----
---------------YRPPRLPS--------------MFLGYLYK--KFFFKSSTAKDGY
E--HDVDWWSKLF--WATGDYH---KSPKYKYKDYYTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPAALKPPHQFLVGPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYM
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDTYQ--PKTLDPIFGTMYELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCLPTS----WAG------
-------NQG-PDPPCLHPC----FHHG-----LSCKLNPPTVHGLGPKMERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNISPRKPKRKASEHSG
YRYELRCIIWQTANVDLVDSNLSGEKTSDIYI-KGWLYGLEDDMQKTDIHYYSLTGEGNF
NWRFIFTMDYLAAECVCIRSQKDYIWSL

PF00168 // ENSGT00550000074414_4_Domain_9 (2189, 2226)

DPTSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLS

ENSGT00550000074414_4_Linker_9_10 (2226, 2282)

DMPFPARHAYQCSLKMMDADSKWPPFLQYKHFSLFKKKTVTGWWPCQVLD-DGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEILSEREALIRPAGRGQSEPNQYPTLHPPLRPESGLKWFRSPVQNLCRGL
WKRYRFKILASLVILITALLLFNFLYSAPHYLAMHWIKPELRLSPPIKVV-NIITPLNTS
NANSSILQTPDLNP----------KPTIDRGFKLSTYPRIT--------------

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-----------------NMK-----ASSPQLLVEFGDESLRTEPISDFQTNPNFPESIYL
LIVLSWGLQYMPTQEAYALPLVVKVVDIWLFGQRTVVGQANIDFLQPYFCDPWAQD----
---------------YVPPQLPK--LSVMKQE-----GFLGQLYK--KFFFKSSTTKDAY
E--HEVDWWSKLF--WAIGDEH---KSPKYKYKDYHTLKVYDCELEAVPAFQGLQDFCET
FKLYQEQPKLDSPVI-GEFKGLFRIYPFPENPEAPKPPHQFVVWPEKENFPQLCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1940)

RVYM
VRAINLQPQDYNGLCDSYVILKLGKTELGNRDKYQ--PNTLDPIFGQMFEFTCNIPLEKD
LEIQLFDFDLFSPDDKIGTTVIDLENRLLSGFGARCGLSKSYCQSGP--FKWRDQLPPSY
LLELHAKRKG-LPPPLFNPEDDSIIYNEKIFKLMHFEPDPPTVPGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKVGPPGPRVDISPRKPK--------
-RYELRCIIWQTSHVDLVDSSLSGQKSSDIYV-KGWLYGLEEDMQKTDIHYHSLAGEGNF
NWRFIFTMDYLAAERVCIHSQKEYI

PF00168 // ENSGT00550000074414_4_Domain_9 (2186, 2215)

WSLDPTSTKFPPRLIIQVWDNDIFSPDDFLDSGVL
ELDLSDMPFPARHAYQCSITVMNPDPKWPSFLQHKSFSLFKKKTVTGWWPCQVLD-EGKW
RLSGKVKMTLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRAENTLLWLRLPVLNFCHAL
CKRYRYKIIAFVVILLIALLLFNFIYSAPHYLAMKWIKPDLRLYPPVKIV-NIITPLNSS
NANSSFLQTSN----------RNLT---DHGLKL---------------------

MLRLVVQSAKIDPPLAPLPRPCMSIDFRAWDGKGRGRMLTSLCPPQT-LIWHLWNRPLEN
DSFLQVTLQDMGSQKKE-----------------RFIGLATVLLKPLLKQPSEVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSNQ--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TVHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 261)

QVRVKVFEARQLMGNNIKPVVKVSI
TGQQHQTRIKMGNNPFFNEIFFQNFHG-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKL---LYGD
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLKK-------------------HQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCPDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGACIPDSV-RDGLAYRGRVFL-ELITQIKSYQDST-IKDL---SHEV
TRI---EKHQNRQKYGLCVIFLSCTMMPNFEDLIHFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNRKD-PALLY

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 787)

QWEKLLRELAEDCKRPLPCMTY-QPKATSLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

QA----KPKDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSPAGALHSGRLCGKIQTLFLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLRQGDMAVYAEM---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTNFQPPLGWHWQDSWTVEPQRRFLLDIDINKSQVLEEVYENQGRDT
RGVWGPAAIPNTDVNGQPMEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNHGE----LSHE-QETLSFLQL-GLA--KG-EEE
GWEYDTF-GSKFHLNPQPQSRFRRRCWRRRLAPNKDKGIAPIFLLEGSL-----------
--------------------------AMDLKYHAG--KEEDSKTWPWGLDR-Q--FRDPQ
--------RQDT-RPPNLPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQHLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLVKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLVMWNADSGQDRRGWSEVRCSLLL--------------------------------
-------VLPDYWIQ-------------------------SSHPEKDYLGGGGRQERNEE
VLA----RAR-------------------------------------APGKPWPRPPLSS
LKS-----------EPMSELWLS--LAHPLLF-----QFLGYLYR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRIYPFPENPEAPKPPLQFLIWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK--------
-RYELRCIIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEADF
NWRFIFTMDYLAAEHMCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFMWLQSPVQNFCYIF
WKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTIDHEWKLHPGPTNHLSDIFPELPAPGD-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DGLAYRGRVFL-EVVTQIKSRQDSR-MKDL---SNEV
TSV---EKQQYRQKYGLCVIFLSCTMMPNFKDLIQFEVSIG-HYGNKMDLSYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSYWEDVSVRMNCLNLLHFTRDRLVSGARG
VHGRIRIPCSMSQVSPVLTRRFSPAASSCPTPHLDPYP-YPQATDLDRKRWQLRSFLLQE
LAQKAREA----KPRDMVATVEGWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQV--SLPD
VMIWLMSKEQRVAYAQVPAHSILFSPTGALYSGRFCGKTQTLLLQYPEG---------EG
PKDTLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1296)

GNVMDSKHLQLLRQGEVVVYAET---YENQAKNKDQWGQQGLSRC
PNFSDVMGRKALPKEDFKAPHGWHWQGQWRVEPQRRLLLDTDINKSQVLEEVYENQYRNT
TGAWVPAAVPNTDMDGHAVEARESMKCPQGWYIKKNWTVELNHAVDNEGWEYGVGIQPSG
LPRVWNSVEKTYYSHRRRRWARVRYRNHGE----LSHE-QETLSFLQL-----------Q
GWEYGTF-GSKFHLNPQPQSQFRRRCWHRRLAPDKDKGIAPIFCLEGSLGRL--------
------------------------------------------------LSKRLGDAWRPA
--------PEDI-QLPNLPFIYC-IFDKPHYYQLF

PF00168 // ENSGT00550000074414_4_Domain_6 (1296, 1354)

CYIYQARNLMSN-----QIHSFQGP
FIRLIFLNHSQCTQTLRS---SAAPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1600)

QHLFLYENPQDTKESPPLVMLELWQRS
SQG-KESLWGRTMWSPVVWLDVQN---------------RILPPMRWHPLVKELGNEEGE
ILASCELILETEPAVPNSTSSGKAGAWEQEHWAWMPILSVPWKNGVYTLPKSIEPTLKKM
AIE---------------------------------------------------------
---------ILVWGLRNMKQ-----VRAPQLLVECWEES

PF00168 // ENSGT00550000074414_4_Domain_7 (1600, 1660)

LQTEPIRGFQTNPNFTESVLF
L------TLFMPTEEAYALPLMLKVVDNWDFGQQTVVGQ

ENSGT00550000074414_4_Linker_7_8 (1660, 1857)

ASIDSLQPYFCDPWAED----
---------------YMPPRPNPDSVGLEKKGQCVFPP-EG--------QNDPLPCQDEY
E--HEVDWWSKLF--WATGDLQ---QPLKYKYKDYHTLKVYDCELEAVPEFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPEAPKPPRQFMVWPQKEDFPQQCLV

PF00168 // ENSGT00550000074414_4_Domain_8 (1857, 1939)

RVYV
VRAINLQPQDLNGLCDPYVILKLGKTTCGNRDKYQ--PNTLDPIFGTMFELSCTIPLEKD
LEIQLYDFDLLSPDDKIGATIIDLENRLLSGFGACCGLSKSYCPSGP--FRWRDQMPPSF
LLERHAKRKG-LPPPLFNTEDDSVFYNGKKFKLQSFEPKPPTAHYLGPKKERLALYLLHT
QGLVPEHVETRTLYTDSQPGIDQGKVQMWVDIFPTELGPPGPPVDIKPRTPK--------
-RYELRCIIWKTAQVDLKDSTFSPENLSDIYV-KGWLFGLEKDMQKTDIHYYSVTGEGNF
NWRFIFTLDYLMAEHVCVLSQKDYIWSLDPTVMKFP

PF00168 // ENSGT00550000074414_4_Domain_9 (2197, 2220)

ARLIIQVWDNDIFTSDDFLG--VL
ELDLSDMPFPARHANLCSIRMMDADPKWPYLLQHKRFSLFKKKTVTGWWPCQVLD-GGKW
RLSGKVKMTLEILSEKEALIRPAGRGQSEPNQYPTLHPPLRNEKWFLWFRSPLQNIFHIF
WKRYRFKMIIFLMIVIIGLLLFNFIYSAPNYLAMSWIKPEL-------------------
-------------------------------------------------------

ML

PF00168 // ENSGT00550000074414_4_Domain_0 (3, 110)

RLVVESAKINPPLSPPPKACVTVYFRDMKKRTRVEEGNDPIWNET-LIWHLWNRPLEN
DSFLQVILQDEGFKKKD-----------------RFIGLSIVLLKQLAQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

RPNEVFFVKNL
TLLNHSMKPTDCTVTLQVAQ---------------IYDQ--------------DTEMTGK
EELLDSTANKVTQQKPMVPSL-TMHRALASKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRLKVFEARQLLGNNIKPVVKINI
AGHQHLTRIKTGNNPFFNETFFQNFHE-VPAKFFEENILIQVVDSAAWRSKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQRNKTVSGVRGYLKV-TICALGMGDQALVDQKL---PYED
GDTQVQIFKSKAVPI-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHFKK-------------------HQSAAT
ALEVELIGDKLRTHTQA-QNDSPVWNQILTFQIQLPCLSSYIKFRVLDCSKRDCREEIGS
ASLCLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 734)

GEEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKAPFRT-P-EKGTCILDAV-KDGLTYRGRIFV-EIITQLKSHQDSV-IMDL---SREV
AQI---ERQQYRQKYGLCVIFLSCTMMPKFKDLIQFEVSMG-HYGNQMDPNYKPLVSTTQ
---HSPVIYDG--TIYHYVPWYNTKPVATVTSQWEDVSFRMNCLNLLHITRDHLKANLDT
LKSI-RNPKD-PA

PF08165 // ENSGT00550000074414_4_Domain_4 (734, 787)

LLQQWEKLLRELIEDCRRPLPCMTA-QPKANNLDKNKWQLRNHLLRQ
LAQRAS

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRKMVVTAEDWLR-----------------RLNAVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VMIWLTSKQQRVAYARVPAHTVLFSPAGPLSSGKFCGKIQNLFLQYPEG---------EG
E-NTLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVVHSKNLKLLQQGNMVVYAET---YENQAKYKDQWGEQGLYYC
PTFSDVMGRKAVPKSDFKAPVGWHWQGDWIVEPQRRLLLDTDINKSQVLEEVYENQSRKA
TGAWVPAAIPNTDVNGQPVEALENVKCPQGWHFKNNWIVELNHAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSYRRRRWVRVRFRNPREQGQELSQE-METLSFLQMQDLS--GE-GKE
GWEYGTF-ESKFNLDPQPTSRFRRRCWHRRLVPKKEKGVASIFLLEGSLAVELE------
-------------------------------SQ-P--KKEQNKTWSLQ--H-WKDSWKHT
--------PENP-RTPTMPFIYC-IFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1386)

QLFCYIYRARNLMYN-----QILTFQEP
FIRVVFLNYSLCTQTLRS---SAAPTWSQTLIFQHLMLFENPKDTRENPPLVVLELWQHD
SRG-N

ENSGT00550000074414_4_Linker_6_7 (1386, 1588)

KILWGRSMWPPVVWLDLQG---------------WALTPLRWHPLVRELGEEEGE
ILASCELILETEKL---------------K-DTPLPILSVPCKNGIYTLPKNIQPEVKMM
AIE---------------------------------------------------------
---------IMAWGLRNMKA------H

PF00168 // ENSGT00550000074414_4_Domain_7 (1588, 1664)

HPQLLVECGEESLRTEPISNFQENPNFPKSNFF
L------TVFMPLEETHALPLVVKVVDNQVYGQQIVVGQANID

ENSGT00550000074414_4_Linker_7_8 (1664, 1856)

FLQPYFCDPWALN----
---------------YTPVKLPG--VILPP----------STLYK--KLWLESSKDEDDY
E--HDVDWWSKLF--WATGDAD---SSVPYKYKSYHTLKVYDCELEAVLAFQGLQDFCQT
FKLYQEKPKVDSPVV-GEFKLGYLSIYSPPDPEAPKPPRQFSSWPETEDFPQPCM

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQMKLGSRDSYY--PNTLDPIFGTMYELTCNIPLEKD
LEIQLYDFDLITADDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2125)

LLSGFGARCGLSKSYCKSGP--FRWRDQLSPSH
LLTRYARQKG-LPPPIFDLENDSVFYNGKRFELQSFESTPPTFEGLGPKKERLALYILNT
QGLVPEHVETRTLYSNSQPGIDQGKIQMWVDIFPKMLGPPGPRVNISPRKPK--------
-RYELRCIIWSTSHVDLVRQTLSK

PF00168 // ENSGT00550000074414_4_Domain_9 (2125, 2233)

EKMSDIYV-KGWLSGLEKDMQKTDVHYHSLTGKAIF
NWRFIFTMDYLATERVCVQSQKDYIWSLDPTSMKFPARLIIQIWDNDFFSPDDFLG--VL
ELNLSDMPLPAV

ENSGT00550000074414_4_Linker_9_10 (2233, 2278)

SSKQCSLKMMETDSKWPS-MQPKRISLFKKSNVTGWWPCQVHD-G

PF16165 // ENSGT00550000074414_4_Domain_10 (2278, 2372)

DKW
RLSGKVKMTLEMLSEREALIRPAGRGQSEPNQFPTLHPPVRNDT--WWYQSPVKNFCYVF
WKRYRTKIICCAVVLVLGIILFNFVYSTPNYLAMAWIKPELRLNPPIKIV-NLIGSVNTS
SINSTVFSMEG----------P----------------RNHMKDVVPEIPGPQG-

MLRLVVQ

PF00168 // ENSGT00550000074414_4_Domain_0 (8, 106)

SAKIDPPLAPLPRPCMSIDFRDVKKRTRVVEGNDPVWNET-LIWHLWNRPLEN
DSFLQVTLQDTGSQKEES-----------------FIGLATVLLK

ENSGT00550000074414_4_Linker_0_1 (106, 216)

PLWKQPSKVLFVKDL
TLLNHSMKPTDCTVTLQVAH---------------MSHR--------------DIEKTGA
EDLLGITAREAARQKLMVPGS-TAHRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 265)

QVRVKVFEARQLMGNNIKPVVKVSI
AGQQHQTRIKMGNNPFFNEIFFQNFHE-VPAKFFDETILI-----------------QTD
IGFIYHSPGHTLLRKWLGLCQPNNPGSGVTGYLKV-TICALGVGDQALIDQKQ---LYGA
DDTDIQIFKSAVVPI-NMA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 492)

YLQFFIYCAEDLHLSESP---------------EKQQSVNP
QLEVELIGEKLRTHMQT-QTDNPIWNQILTFRIQLPCLSSYIKFRVLDCHRKDCSDEIGT
ASLSLNQISST

ENSGT00550000074414_4_Linker_3_4 (492, 737)

GEEIEG-------------------------VYSGFLPCFGPSFLTLHG
GKKAPFRI-Q-EEGARIPDSV-RDGLAYRGRVFL-ELVTQIKSCQDST-IKDL---SHEV
TRI---ELCLPQIYF------LTLI------CMIHFELICIEKRPPRIPQ------TPHP
---SMCLCVSG--NIYHYVPWYNIKPVVAVTSNWEDVSFRMNCLNLLHFTRDRLKANLDT
LKST-RNPKD-PALLC

PF08165 // ENSGT00550000074414_4_Domain_4 (737, 786)

QWEKLLRELVEDCKRPLPCMTD-QPKATNLDRKRWQLRSLLLQE
LAQKA

ENSGT00550000074414_4_Linker_4_5 (786, 832)

KQA----MPRDMVATAEDWLY-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--GLPD
VMIWLVAKEQRVAYAQVPAHSVLFSRAGALHSGRLCGKIQTLLLQYPEG---------EG
QKDVLPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVTDSKDLQLLCQGDMAVYAET---YENQAKYKDQWGQQGLYRC
PNFSDVMGNKTLPMTDFQPPLGWHWQDSWTVEPQRRLLLDTDINKSQVLEEVYENQGRDI
RGAWGPAAIPNTDVNGQPTEARENVKCPQGWHFKKDWVVELNHAVDSKGWEYGVGIPPSG
LPQVWSPVEKTYHSCRRRRWARVRFRNRGE----LSRE-QETVSFLQL-GPA--EG-EED
GWEYDAF-GSKFHLHPQPRSRFRRRCWRRRLVPDKDKGVAPVFLLEGSL-----------
--------------------------AMDLKHRAG--KEEESKPWPWGLDR-Q--FRDPQ
--------RQDA-RPPNMPFIYC-TFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1355)

QLFCYIYQARNLVSN-----QILTFQGP
FIRVVFLNHSQCTQTLRS---SAGPTWAQTLIFQ

ENSGT00550000074414_4_Linker_6_7 (1355, 1572)

HLLLYENPQDTKESPPLVVLELWQRD
SWG-KESLWGRSMWPPVVWLDLQD---------------RILPPMRWHPLMKELGKEEGE
ILASCELILQTEKL---------------G-EKQLPILSVPWKNGAYTLPKSIQPTIKRM
AIEVLATWDGDGGQGRRGWSGVSH---------------PEKDYLGG-GGRQER--N---
-----EEVLIL

PF00168 // ENSGT00550000074414_4_Domain_7 (1572, 1665)

AWGLRNMKK-----ASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESV
LVL----IVLMPTEEAYALPLVVKVVDNWAFGQQTVTGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWAQD----
---------------YVHPKLPS--------------TFLGYLSR--KFWFKSSKAEDEY
E--HEVDWWSKLF--WAT-DEH---KSLKYKYKDYHTLKVYDCELEAVPAFQGLQDFCQT
FKLYQEQPKLDSPVV-GEFKGLFRVYPFPENPDAPKPPLQFLAWPEREDFPQPCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGSRDMYQ--PNTLDPIFGTMFELTCNIPLEKD
LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALHLLHT
QGLVPEHVETRTLYSDSQPGIDQGKVQMWVDIFPKKLGPPGPPVNINPRKPK--------
-RYELRCVIWKTANVDLVDDNLSREKTSDIYI-KGWLYGLEKDMQKTDIHYHSLTGEANF
NWRFIFTMDYLAAERVCVQSQKDYIWSLD

PF00168 // ENSGT00550000074414_4_Domain_9 (2190, 2230)

ATSMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAQQCSIRMMDADPKWPYFLQYKHFSLFKKKTVTGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRPYTSFIWLRSPVQHFCSVF
WKRYRFKLIAFMVISILALLLFNFIYSAPHYLAMSWIKPQLQLYPPIKIF-NIITSLNTS
NASSSILPTQD----------PNLKPTTDHEWKLHPGPTNHLSNIFPELPAPED-

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 110)

LRVVVESASINPPLSTTPKAFVTVYFRDMKKITRVEEGHDPIWNET-LIWHLWNQPLEN
DSFLKVILQDSVSKKKE-----------------RFIGLATVPLKRLAQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

RPKEVVFVRDL
ILLNHSMKPTNCTVTLQVAQ---------------IYDQ--------------DTEMTGN
KELLGSTVNEVTQKKLMVSGL-PMHRALASKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 302)

QVRVKVFEARQLLGNNIKPVVKINI
AGQQHLTRIKMGNNPFFNEIFFQNFHE-VPAKFFEENISIEVVDSAASRSKAEIGRFQTD
IGFIYHSPGHTLLRKWLGLCQRNKTTSGVRGYLKV-TICALGVGDQALVDQKL---PYEQ
-NTQVQIFKSTEVPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQFFIYCAEDLHFGT-------------------HKSATP
VLEVELIGDKLRTKPQS-PSDNPIWNQILTFQIQLPCLSSYIKFRVMDCSRYKCQDEIGS
ASLCLSQISSTG

ENSGT00550000074414_4_Linker_3_4 (493, 735)

EEIQG-------------------------MYSGFLPCFGPSFLTLRG
GKKPPFRT-S-EEGTCIMDAV-QHGLDYRGRIFV-EIVTKIKSQQDSV-MKDL---SQEV
TQV---EMQYYRQKYGLCVIFLSCTMMPKFKDLIQFEVSMG-HYGNKMDPNYKPLVSTTQ
---YSPVIYDG--TTYHYVPWYNTKPVVAVTSNWEDVGFRMNCLNLLHITRDRLKTNLDI
LRSI-RNPGD-PAL

PF08165 // ENSGT00550000074414_4_Domain_4 (735, 787)

LQQWEKLLKELQEDCQRTLPCMTD-QPRANSLDRNKWQLRSQLLQQ
LAQMAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPVNMVGTGKEWLH-----------------RLNAVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VLIWLMSRQQRVAYARVPAHTVLFSPAGPLSSGKFCGKIQNLLLQYPEG---------EG
Q-DTFPASLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVKYSKNLKLLQQGSMVVYAET---YENQAKIKDDWGQQGLYHC
PNFSDVMGRKALPKTDFKAPPGWHWKDDWVVEPQRRLLLDIDINKSQVLEEVYENQLRNA
TGAWVPAAIPNTDVNGQPVEALENMKCPQGWHFKKNWMVELNHAVDSQGWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRVRFRNHKELGQELSQE-QETLSFLQMQDLS--EE-GKE
GWEYGAF-DSRFHLDPQPTSRFRRRCWHRQLAPNKDRGVASIFLLEGSLAVEQK------
-------------------------------DQ-P--RKEMEKTRSWQ--P-WKD-LRHT
--------PEDP-RIPTTPFIYY-ILNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1386)

QLFCYIYQARNLMYN-----QILTFQEP
FIQVVFLNHSLCTQTLRS---SAAPTWSQSIIFQHLLLFEDPKDTRENPPLVVLELWQHD
SRG-N

ENSGT00550000074414_4_Linker_6_7 (1386, 1594)

KILWGRSMWPPVVWLGLQD---------------WVFTPLRWHPLVRELGEEEGE
ILASCELILETQKL---------------K-ELHQPILSIPCKDGIYLLPKNIQPTMKMM
AIE---------------------------------------------------------
---------IMAWGLRNMTK-----VRYPQLLL

PF00168 // ENSGT00550000074414_4_Domain_7 (1594, 1665)

ECGGESLKTEPISNFQENPNFPTSTFF
F------TVFMPLEETHAQPLVVKVVDNQEYGQQIVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWSLN----
---------------YTTVKLPT--LSVKKPD-----TFLDFVYK--KFWFDSSKEEDVY
E--EEVDWWSKLF--WATGDAD---KSLNYNHKSYHTLKVYDCELEAVLTFKGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPDALKPPRQFSAWPEIEDFPQMCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYY--PNTLDPIFGMMYELTCNIPLEKD
LEVQLFDFDLITADDEIGSTVIDLENRLLSGFGARCGLSKSYCKSGP--FKWRDQMTPSY
LLYRYAKQKG-LPPPVFDVEGDSLYYNGETFKLQSFESVPPTYKHLGPKKERLALYILNT
QGLVPEHVETRTLHSNSQPGIDQGKIQMWVDIFPKMLGPPGPQVNISPRKPK--------
-RYQLRCIIWSTAEVDLVRETFSREKMSDIYV-KGWLFGLEEDTQKTDVHYHSLTGEATF
NWRFIFTMDYLTTERACIQSQ

PF00168 // ENSGT00550000074414_4_Domain_9 (2182, 2230)

KDYIWSLDPTSTKFPARLMIQIWDNDFFSPDDFLG--VL
ELDLADMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2280)

PAQNIKQCSLKMMETDSKWPF-TPQKHISLFKKTNVTGWWPCQVLD-GDK

PF16165 // ENSGT00550000074414_4_Domain_10 (2280, 2371)

W
RLSGKVKMTLEMLSEREALIRPAGRGQSEPNQFPMLHPPERNDSLLLWYQSPIKHFCYAV
CKRYRSKIICLVVTLVIGFILLNFVYSAPSYFAMNWIKPQLRLSSPIRIV-NLIGTVNTS
NVNSSILTMEG----------STDH----------SSL------VFPGAPAP---

MLRLVVESAKISPPLSPPPRPSMFVYFRGKSHE----------PQET-LIWHLRNRPLQN
DSFLQVTLQDMGSKKKE-----------------RFIGLATVLLKPLVKKPSEVLFVKDL
TLLNHSMKPTDVSWAPGRVD-------------------DEAQAADEAK-PSLDCVSTGD
EGLLAITAQEVARQKWMFPSP-TVNKTLSPKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 289)

QVRVKVFEARQLLGNDIKAVVKVLI
GGYQHHTRIKMGNNPFFNEIFFQNFYE-VPAKFFDETILIQVRSWFQG

ENSGT00550000074414_4_Linker_1_2 (289, 321)

R-----------
--RMEMGWGHILLRKWLGLC

PF08151 // ENSGT00550000074414_4_Domain_2 (321, 351)

QPNEPSSGVRGYLKV-TICVLGVGDQAPVD

ENSGT00550000074414_4_Linker_2_3 (351, 427)

QKL---AYEA
GDTETQVFKSTVVPV-SMACLQFFVYCAEDLHLTGTD--TA-------------------
-----L

PF00168 // ENSGT00550000074414_4_Domain_3 (427, 469)

GCSQLKTHVQP-QTDTPIWNQILTFRIQV-------------

ENSGT00550000074414_4_Linker_3_4 (469, 738)

LPRNRCQDEIGT
VSLSLNQISSTGAEIEGKQAPAPDLLLLPHLAPPLSPSPPPGMYSGFLPCFGPTFLTLRG
GKKAPFRI-Q-EEDSNIPNAV-KDGLAYRGRVFL-EIITHMKSHQDTI-MKDL---SHDV
IRK---R--YPRRKEPLC--------PPYFRDLIQFEVSIG-HYGNKMDLSYKPLVSTTQ
---YSPVIYDG--NIYHYVPWYNTKPVVAVTSYWEDVSFRMNCLNLLQFTRDRLKANLDT
LKSM-RNPRD-PALLPH

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 787)

WEKLLRELVEDCKRPLPCMTD-QPKATDLDKKRWQLRSLLLRE
LAQNAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

KA----QPRDMVATVESWLC-----------------RLNAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQV--SLPD
VMIWLMSREQRVAYAQVPAHSILFSPAGALHSGRFCGKTQTLLLQYPEG---------EG
EKDTLPAQLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVKDSKDLQLLRQGEVVVYAET---YENQAKYKDQWGQQGLHRC
PNFSDVMGRKAIPKEDFREPHGWHWQGKWTVEPQRRLLLDTDINKSQVLEEVYENQRRDT
TGAWVPATIPNTDVKGEPVEARENMKCPKGWHVNDNWAVELNHAVDNEGWEYGMGIQPSG
LPLVWNSVEKTYYSRRRRRWARVRYRDHGR----LSHE-QETLSFLQLDE---------A
GWEYGIF-GSKFHLNPQPQSQFRRRCWHRRLVPNKVKGIAPIFLLEGSLVKL--------
--------------------------------QGD---GCLL--P---ESCLPKSSWRAP
--------PE-MTQPPTLPFIYY-IFNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSN-----QIQTFQGP
FIRLVFLNHSQCTQTLRS---SAAPTWAQTLIF

ENSGT00550000074414_4_Linker_6_7 (1354, 1575)

QHLLLYENPEDTKESPPFVVLELWQRD
PKG-KESLWGRSMWAPVVWLDVQK---------------RILPPMRWHPLVKGLEDEEGE
ILASCELILETEVLG-----------------ERLPILSVPWKNGIYILPKSIQPTLRKM
AIE---------------------------------------------------------
---------MLAWG

PF00168 // ENSGT00550000074414_4_Domain_7 (1575, 1663)

LRNMKQ-----VRSPQLLVECWDESLQTEPIRDFQTNPNFTQSALF
L------TLHMPTDETFALPLVLKVVDNKDFGQQTLVGQANI

ENSGT00550000074414_4_Linker_7_8 (1663, 1856)

DSLQPYFCDPWAED----
---------------YMPPQPPRMALS---PHPCP--G-LSYLYE--KFWFKSSKAEDDY
E--HEVDWWSKLL--WATGNIP---KTVKYKYKDLHTLEVYDCELEAVPAFRGLQDFCQT
FKLYQERPQLDSPVV-GEFKGLFRVYPFPENPEAPKPPRQFLLWPKKEDFPQQCV

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYM
VRAINLQPQDTNGLCDPYVILKLGDTKVGNRDKYQ--PNTLDPIFGMMFELSCTIPLEKD
LEIQLYDFDLLSPDDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2128)

LLSGFGARCGLSKSYCQSGP--FRWRDQMPPSL
LLEHHAKRKG-LPPPLFSPEEDSVLYNGKKFRLQSFELKPPTARYLGPKKERLALYLLHT
QGLVPEHVETRTLYSNSQPGIDQGKVQMWVDIFPKKLGPPGPPVNISPRKPK--------
-RYELRCIIWKTALVDLKENSLGSEKM

PF00168 // ENSGT00550000074414_4_Domain_9 (2128, 2220)

SDIYV-KGWLFGLEKDMQKTDIHYHSEMGEGIF
NWRFVFTLDYLAAEQMCVLSQKDYIWSLDPTVMKFPARLVIQIWDNNIFSTDDFLG--E

ENSGT00550000074414_4_Linker_9_10 (2220, 2282)

M
QELLLADSFSLG---SGILEMTDADPKWPHFLQYKHFSLFKMKTVTGWWPCQVLN-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2373)

LSGKVKMTLEILTEKEALIKPAGRGQSEPNQYPTLHPPPRSDMLFMWFRSPVTNFIRVV
WRRSRFKIIAIAIILVMGLLLFNFIYSAPNYLAMNVIKPELRLNAPVEFQANIVYSLNTS
DTNPSIPTTHH----------LNM---------------------FPQLPAPQA-

MLRLV

PF00168 // ENSGT00550000074414_4_Domain_0 (6, 108)

VESAKIEPPLSPPPRPCLTVYFRDIKKRTRVVEGNDPTWNET-LIWHLWSRPLEN
DSFLQVILRDMGSKKKE-----------------RFIGLATVLLKPL

ENSGT00550000074414_4_Linker_0_1 (108, 216)

VKRPREVLLVKEL
NLLNHSMMPTDCTVTLQVAH---------------VIHR--------------DTEKTGR
ADPLGMITREATQQKLLVPGSEGMYRALSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 305)

QVRVKVFEARQLMGNNIHPLVKVTI
AGQQHHTRIKMGNNPFFNEIFFQNFNE-VPAKFFDEIILVQVLNSSAMRSKAEIGRFQVS
P--SSASPGHTLLRKWLGLCLPNEPSSGVRGYLKV-TICALGVGDQALVDQKL---LYGA
-DTDIEVFKSAAVPM-TTAY

PF00168 // ENSGT00550000074414_4_Domain_3 (381, 492)

LQLFIYCAEDLHL------------------------TSP
VLEVELIGEKLRTNVQH-QTDNPIWNQILTFQIQLPCLSSYIKFRALDCAASDCLEEIGT
ASLSFSHISST

ENSGT00550000074414_4_Linker_3_4 (492, 738)

GEEIEG-------------------------KPSGPPPAQGSR------
------PD-S-TQ--SIPGAI-GDGLSYRGRVFL-ELITQVKSHQDST-IKDL---SREV
ARI---EKHQNRQKYGLCVIFLSCTMMPNFKDFIQFEVSIG-HYGNKMDLNYKPLVSSTQ
---YSPVIYDG--NIYHYIPWYNTKPVVAITSSWEDVSFRMHCLNLLQFTRDRLKANLDT
LKSI-RNPRD-PALLPQ

PF08165 // ENSGT00550000074414_4_Domain_4 (738, 787)

WEKLRRELAEDCRRPLPCMTG-QPKATKLDRKRWQLRSLLLQE
LAQKAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPRDMVATVEGWLR-----------------RLGAVLPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQM--SLPD
VMIWLMAKERHVAFARVPAHTVVFSPAGPLHSGRFCGKIQTLLLQYPEG---------EG
QQDAPPAHLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNIADSKDLQLLRQGDMVVYAET---YENQAKYKGHWGPQGLYQC
PNFSDVMGHKALPKSEFKAPPGWHWQDSWMVEPQRRFLLDIDINKSQVLEEVYENQERNV
KGTWVPSAIPNTDVNGQPTEARDRVTCPQGWHFKKDWAVELNHAVDSEGWEYGVGIPPSG
LPRVWTSVEKNYHSCRRRRWVRMRFRNHE----ELGRE-EQTVSFLQMQGLA---SEGKE
GWEYGSL-GSTFHLDPQPQSHFRRRCWHRRLAPNKDTGVAPIFLLEGSLAVDLKH-----
-----------------------------------SPKKDESKAWSWAQ---VQDSWRPG
--------REDW-RLPSMPFIYC-TLDKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1354)

QLFCYIYQARNLMSN-----QILVFQEP
FVRVIFLNYSQCTQHLPS---SSVPSWAQTLIFQHLLLHESPQDTRESPPLVVLELWQRD
ARG-KESLWGRSMWPPVVRLDLKN---------------WVLPPLRWHPLVKELEKEEGE
ILASCELILETEKL----------------REKHLPLLSVPWKDGVYTLPKSIQPTMSKT
AIE---------------------------------------------------------
---------ILAWGLRNMKQ-----ARHPQLLVECGGEALRTEPIRDFPTNPNFPESALL
L------TVFMPKEESYVQPLILKVLDNQDFGQQTVVGQAIVDFLQPYFCDPWARD----
---------------YLVPVPAL--GCWP--H-----LVLGFLYE--KFWLKFS--KDEY
E--HEVDWWSKLF--WATGDDQ---KSPKYKYQDYHTLKVYDSELEAVPAFQGLQDFCRT
FKLYQERPKVDSPVA-GEFKGLFRIYPFPENPEAPKPPRQFLAWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGSTKLGSRDAYK--PNTVDPIFGTMFELTCTIPLEKD
LHIQLLDFDLFLLDDEIGTTVIDLENRLLSGFGARCGLSKSYCQSGP--FRWRDQMPPSY
LLERYAKRKG-LPPPVFDPKGDSVLYRGKKFNLQNFEPKAPTVPGLGPKKERLALYILHT
QGLVPEHVETRTLYSDSLPGVDQGKVQMWVDIFPQKLGPPGPPVKISTRKPK--------
-RYELRCVVWKTAHVDLVDEALSREKMSDIYI-KGWLLGLEKDMQQTDIHYHSVTGEAIF
NWRFIFTMDYLAAERMCTESEKDYI

PF00168 // ENSGT00550000074414_4_Domain_9 (2186, 2232)

WSLDPTSTKFPARLIIQIWDNDTFTSDDFLG--ML
ELDLSDMPRPA

ENSGT00550000074414_4_Linker_9_10 (2232, 2282)

RHAKQCSLQMLDAEPKWPYFFPHKRFSLFKKKTVTGWWPCQVQQ-DDKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2373)

LAGKVKMTLEVLSEKEALARPAGRGQSDPNQYPTLYPPLRAGKSFMWLRSPVRYLFFGL
CRRYRCKIISFFILLVIAFMLFKFIYSAPNYLAMSLIRPGLRMQPPIKIY-NLITSPTVS
SANPAPLATQA----------PSLQPVTDHQLPLLQVP-----------------

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-----------------MKK-----ASSPQLRVEFGEESLTTEPIKDFQTNPNFPES--V
LIL----TLYMPTEEAYALPLVVKVVDNWAFGQRTVTGQANIDFLQPYFCDPWAQD----
---------------YVHPKLPI--LSVKKHR-----HFLGYLYE--KFWFKCSKAEDEY
E--HEMDWWSKLF--WATGDDH---KSLKYKYKDYHTLKVYDCELEAVSAFQGLQDFCQT
FKLYQEWPKLDSPVV-GEFKGLFRIYSFPENPEAPKPPHQFMVWPEREDFPQLCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYV
VRAINLQPQDYNGLCDPYVILKLGKTELGNRDTYQ--PNTLDPIFGTMFEFTCNIPLEKD
LEIQLYDFDLLSPDDKIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2120)

LLSGFGAHCGLSKSYFQSGP--FKWRDQMSPSS
LLERYARRKG-LPPPLFSPKEDTVIYNGKKFKLQSFEFKPPNVHGLGSKKERLALYLLHT
QGLVPEHVETRTLYSDAQPGIDQGKVQMWVDIFPKKLGPPGPQVNISPRKPK--------
-RYELRCIVWKTANVDLVD

PF00168 // ENSGT00550000074414_4_Domain_9 (2120, 2230)

VSLSKEKTSDIYV-KGWLYGLEKDMQKTDIHYHSLTGEGNF
NWRFIFPMDYLAAEHVCVQSQKDYIWSLDPTLMKFPARLIIQVWDNDIFSPDDFLG--VL
ELDLSDMPL

ENSGT00550000074414_4_Linker_9_10 (2230, 2282)

PARHAKQCSIRMMNPDPKWPYFLQHKHFSLFKKKTATGWWPCQVLD-GGKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2372)

LSGKVKMTLEVLSEKEALIKPAGRGQSEPNQYPTLHPPLRTDTTLTWLRSPAKHFCRVF
WKRYRFKFIALTVILIIALLLFNFIYSAPHYLAMNWIKPELRLHPPIQIV-NVITSPNTS
NANSSILITQE----------PHLKPTTDHELKLPQGPKNHLSDIFPEFPAP---

M

PF00168 // ENSGT00550000074414_4_Domain_0 (2, 110)

LRVVVESATINPPLSPTPKACVTVYFREMKKRTRVEEGNDPIWNET-LIWHLWNQPLGN
DSFLKVILQDSGSKKKE-----------------RFIGLATVLLKQLVQ

ENSGT00550000074414_4_Linker_0_1 (110, 216)

RPNEVFYVKNL
TLLNHSMNPTDCTITLQVAQ---------------IDDQ--------------GTKMTGH
GELLDSTVSEVTQKNQMVPGF-PTH--LSSKPQHF

PF00168 // ENSGT00550000074414_4_Domain_1 (216, 303)

QVRLKVFEARQLLGNNIKPVVKINI
AGKQHLTRIQMGNNPFFNEIFFQNFHE-VPAKFFEENILIEVVDSAASRSKAEIGRFQID
IGFIYHSPDHTLQRKWLGLCQRNKTTSGIRGYLKV-TICALGVGDEAPVDQKL---PYED
-DSQVKIFKSTQVPV-SLA

PF00168 // ENSGT00550000074414_4_Domain_3 (380, 493)

YLQFFIYCAEDLHFRN-------------------PQSATP
ALEVELIGDKLRTYPKS-QSDSPIWNQILTFQIQLPCLSSYIKFRVLDCSKSNCRDEIGS
ASLCLSQISSTG

ENSGT00550000074414_4_Linker_3_4 (493, 734)

EEIQG-------------------------MYSGFLPCFGPSFLTLRG
GEKPPFRT-T-EEGTCILDAVNKDGLAYRGRIFI-EIVTKIKSQQDSV-MKDL---SQEV
IKV---EMQQYRQKYGLCVVFLSCTMMPKFKDLIQFEVSMG-HYGNKMDPNYKPLVSTTQ
---HSPVIYDG--TSYHYVPWYNTKPVVAVTSNWEDVSFRMNCLNLLHVTRDRLKTNLDI
LKSI-RNPRD-PA

PF08165 // ENSGT00550000074414_4_Domain_4 (734, 787)

LLQQWEKLLKDLQEDCRGPLPCMTD-QPRANNLDKNKWKLRSYLLQQ
LEQRAK

ENSGT00550000074414_4_Linker_4_5 (787, 832)

EA----KPVNMVGTAEDWLR-----------------RLNTVIPE

PF08150 // ENSGT00550000074414_4_Domain_5 (832, 916)

PQE--SLPD
VLIWLMSGQKRVAYARIPAHTVLFSTAGPMSSGKFCGKIQNLLLQYPEG---------EG
Q-NILPAYLRVCMWL

ENSGT00550000074414_4_Linker_5_6 (916, 1293)

GNVKHSKNLKLLQQGTMVVYAET---YENQAKIKDDWGQQGLYYC
PNFSDVMGRKALPKTDFRAPPEWHWKADWVIEPQRRLLLDIDINKSQVLEEVYENQSRNA
TGAWVPAAIPNTDVNGQPVEAPENVKCPQGWHFKKNWIVELNHAVDSEGWEYGVGIPPSG
LPQIWNSVEKTYHSCRRRRWVRVRFRNHREVGQKLSLE-EETLSFLQMQDLS--EE-GKE
GWEYGTF-GSRFHLDPQPTSRFRRRCWHRQLAPNEDRGVAPIFLLEGSLEVEQK------
-------------------------------KQ-P--KKEVERTWAWQ--H-WKD-WRRA
--------PEDP-RIPTMPFIYC-TLNKPHYY

PF00168 // ENSGT00550000074414_4_Domain_6 (1293, 1383)

QLFCYIYQARNLMYN-----QVLTFQES
FIQVVFLNHSLCTQTLKS---SAAPTWSQTLIFQHLLLFEDPKDTRENPPLVALELWQHD
SR

ENSGT00550000074414_4_Linker_6_7 (1383, 1590)

G-NKILWGRSMWPPVVWLGLQD---------------WVFTPLRWHPLVRELGEEEGE
ILASCELILETRKL---------------K-ELHLPILSVPCKNGIYMLPKNIRPNMKMM
AIE---------------------------------------------------------
---------IMAWGLRNMKN-----VRYP

PF00168 // ENSGT00550000074414_4_Domain_7 (1590, 1665)

QLLLECGEKSLRTEPISNFQENPNFPTSTFF
F------TVFMPMEESHAQPLVVKVLDNQAYGQQTVVGQANIDF

ENSGT00550000074414_4_Linker_7_8 (1665, 1856)

LQPYFCDPWSLN----
---------------YTTVKLPT--LSIKKPN-----TFLDLVYK--KFWFDSSKDEGEY
E--QDVDWWSKLS--WATGNED---KSLKYNYKSYHTLKVYDCELETIQAFQGLQDFCQT
FKLYQEKPKVDSPVV-GEFKGLFRIYPFPEDPDAPKPPRQFSAWPEIEDFPQMCL

PF00168 // ENSGT00550000074414_4_Domain_8 (1856, 1948)

VRVYL
IRAINLQPQDYNGLCDPYVILKLGQTKLGSRDSYH--PNTLDPIFGTMYELTCNIPLEKD
LEIQLYDFDLITADDEIGTTVIDLENR

ENSGT00550000074414_4_Linker_8_9 (1948, 2170)

LLSGFGARCGLSKSYCKSGP--FKWRDQMTPSY
LLYRYAKQKG-LPPPVFDLEGDSIYYNGEKFKLQSFEPTPPTYENLGPKKERLALYILNT
QGLVPEHVETRTLHSNSQPGIDQGKIQMWVDIFPKMLGPPGPEVNISPRKPK--------
-RYQLRCIIWSTAEVDLVRETFSRDKMSDIYV-KGWLFGLEKDAQKTDVHYHSLTGEAIF
NWRFIFNMD

PF00168 // ENSGT00550000074414_4_Domain_9 (2170, 2232)

YLMTERVCVQSQKDYIWSLDPTSVKFPARLIIQIWDNDFFYPDDFLG--VL
EMDLSDMPLPA

ENSGT00550000074414_4_Linker_9_10 (2232, 2282)

KNSRQCSLKMMETESKWPF-TPQKHISLFKKTNVTGWWPCQVHE-DDKW
R

PF16165 // ENSGT00550000074414_4_Domain_10 (2282, 2373)

LSGKIKMTLEMLSEKEALIRPAGQGQSEPNQFPTLHAPERNDSFLLWYRSPIKNFCYAV
CKRYRSKIICLVVILVIGFILFKFVYSAPNYLTMNWIKPKLRLYPPIKIV-NVIGSVNTS
SLNSSLFTMEG----------SKLKPLKDHGPTLVKYP------GIT--------