Query Results 

------------------------------------------------------------
-----------------MEAGEEMQLVGTS-HMEQKATAPE----------APSPPSTDV
SSPPP--PPTPTSPGGPK-EL----EG--QEP-----EPRPMEEEPGSPW--------SG
PDELEPVVQ-DGQRR------------------VRARLSLAMGLSWGPFHGSVQTGASSP
----GQAE-PSPALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPRSTPDHPVKK-EPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPAAAAADEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTTLHGPLASADLGLAPTP-------SPGLDRKALAEATNGEARAV--PQ------NG
GSSGPPAAPRSIKL----EAVE-EPEAA----------RAPGTGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPVSSPVPGELS---LAGALFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAGAGAGG---AQTGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARRPKAP--RRPVPRR-----------PRSSGPG------ARE
DGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYSVHKRYYCAS-RHDPPPRRPAAPPG-TPGPAVPPAPAPVAPVRTR-RRRKLYE
LH-AAGAPPP--------------------PPPGHAPAPESPRPGSGSGSGPGTAP-ARS
PGPAADGPIDLSKKPRRPPAGA-----------SAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PAPAASPQPEPRGPRDGLGPELQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAGEETQAMDIS-PMEQEAASPEAPAIEDS----PSPPRKDV
SPPTV--PAPPESPEGPE-DMGAQELE--MRPQDEEKEEKEEEAAMTSPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFQGSIQTTALSP
----EQEE-PGPAVTL-LVDEACWLRMLPQALTEAEANSEIY--RKDDALWCRVTKVIPS
GGLLHVLLV-TEPHSTPRHPVQEPRAVEPGGP--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPA-SATEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDGLTGF---
------------------------------------------------------------
QQHSLMHAPLAPADKA---------PTPSSGLDSKALAEVTNGETRVPPQNG--------
GSSETPAAPRTIKV----EAAEEPEAAH-----------ASGPGEP-GPQAPSRTPSPHS
P----IPVRVKTELSSPTPGSSPGPGELA---MAGTLFLPQYVFGPDAGS-TTGSAAPQA
SEILAKMSELVHSRLQQGAGNSGAVG--TPTGLFPGT---KGATCFECDITFNNINNFYV
HKRLYCSGRRAPEDTPVVRKPKAAP--GPARATPGAA-AEADPQRSSPGPG------PRE
EEAGGATT--------------PETEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPVLTPAPGP---AAPALTAPPVRTR-RRRKLYE
LP-GAGAPPPAVGPAPVPVVPVPTSELPSSPRPASA--SAGP-------------APTPS
PGPVPDGPIDLSKRPRRQTPDP---------PAPLPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTA-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRLAHGLQVAKPAACPG
AEPRTPAERA----------------------------PRDSPEGRAPRSPS--------
--------------------------------PGPENTPSDPTDQGVRTPSKGPTVSAPV
SGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SKPR---QIKRSLRDMEAGEEAKGMDIS-PMEQEATAPEAPAIEEP----PSPPREDV
SLPTV--SAPPESPDDPE-DVEGQELE--MRPQDEKKEEKEEESAMASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFYGSIQTRALSP
----EREE-PGPALTL-MVDESCWLRMLPQALTEEEANSEIY--RKDDALWCRVTKAVPS
GGLLHVLLV-AEPHGTPKHPVQEPEE--AGSS--GPVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRASSPV-SATEEKPKETYPNERI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPSDSLTGF---
------------------------------------------------------------
QQHSLRHSPLVPADKA---------PTPSSGLDSKALAEVTNGETRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEAAR-----------ASGPGEP-GPQAPSRTPSPHS
P----NPVRVKAELSSPTPGSSPGPGELT---MAGTLFLPQYVFGPDAGT-TTVPAAPQA
SEILAKMSELVHNRLQQGAGSSGVAG--TPTGLFPGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDPPAVRRPKAAT--GSARAPAGVA-AEPDPPRSSPGPG------PRE
EEASGATT--------------PEAETAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPVPTPAPGP---AAPALTAPPVRTR-RRRKLYE
LP-AAGAPPPAAGPAPVPVVSSPTAELPSSPRPASA--SAGP-------------APTPS
PGPVPDGPIDLSKRPRRQTPDT---------PTALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTT-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPG
AEPRTAAERA----------------------------PRDSPDGRAPRSPS--------
--------------------------------PAPENTPSDQADQGARTSCKGPPAPAPA
PGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
---------------PLPPDGAGAELGEAR-TEGGSGHAGAGDGSAGLAL----PPARCL
CPPGP--S----------------------------PAGGARPRQRPLPWSPGPRSPTCR
PNELELVLQ-DGQRC------------------VRARRGLAEGLSWGPFCGSIQTGASSP
----GQVE-LSPAPTLLLEDEACWLRTLPRALTEAEANAEIH--RKDEALWCRLIRPVPA
GGRLSVLLA-AEPRAAPTHPVKK-EPVEPESP--APAHADIQLLPQQAGMASILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAASPATATPDEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLTGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKAEIYSPGAGHPAAKLPPDSVAGF---
------------------------------------------------------------
QQHTALHGPLASADLGLMPAK-------SPGLDRKALAEATNGEARAGPQNG--------
GGSEPAAAPRSIKV----EAAEELE------------------AEPGP-PAPSRTPSPPS
PGPGLGPVHVKAELSSPTPGSSPGPGA---------LFLTQL------------PAAPPA
SEILAKMSELVHSRLQAGAGVG------APAGLFAGA--PKGATCFECDITFNNVNNFYV
HKRLYCSGRRPPDDAPPARRPKAPS---------APPRAEADAPHSSPGPG------ARE
DEAGSTAE------------AEAEADAGGRGSEGSPSPSSGA-EEDDDPRRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPAHGD-------------PRASAAPPVRTR-RRRKLYE
LHAAGPAPPP--------------AGPAPSP--------ARPRAA--GVAGAAARKRGRE
RLDPVDCPIDLSKKPR------------------LPALADYHECTACRVSFHSLEAYLAH
KKFSCPATPRRLRA----------------------------------------------
-----------------APEDSPAVVCPYCPPNGVVRGDLIEHFRLAHGLLLGKPPAGAG
AEARTPSP----------------------------AAPRDGLNGQDLREAPV-------
------GSPRPGPPPAS--------------SPEAVPAPPSHSDKGVQTP--SQG--TPA
PVPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
--------------------------MDTS-LPEQEAGAPEPEAVREPEPLSPSSPDANP
PHPPS--PPPPTPPGGP------EEME--G---QEE-PETTLEEESGVSW--------SG
PDELELVLQ-DGQRC------------------VRARHSLSEGLSWGSFRGNIQSRASSP
----GQVE-PGPALTLLLGDEPCWLRTLPQALTEAEANAEIY--RKDEALWCRVTKPVPA
GGLLSVLLTAAEPRGTPSHPVKK-EPAEPECL--TPAHADIQLLPQQAGMASILAT--AV
INKD

PF13912 // ENSGT00530000063823_1_Domain_0 (365, 390)

VFPCKDCGIWYRSERNLQAHLLYYC

ENSGT00530000063823_1_Linker_0_2 (390, 435)

AS----RQGTGSPATTATDEKPKETYPNERV
CPFPQCRKSCPSAS

PF13465 // ENSGT00530000063823_1_Domain_2 (435, 460)

SLEIHMRSHSGERPFVCLICLSAFT

ENSGT00530000063823_1_Linker_2_4 (460, 824)

TKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKAEIYSPGAGHPTAKLPPDSLASF---
------------------------------------------------------------
QQHTALHGPLASADLGLAPTP-------SPGLDRKALSEATNGEARATPQNG--------
GSSEPSAAPRAIKT----EASTEEAD-----------------AEPRP-PAAARTPSPPS
PGP--GPARVKAELSSPTPGSSPGPGA---------LFLPQF------------PAAPPA
SEILAKMSELVHSRLQAGPGAQAG----TQAGLFAGA--PKGA

PF13912 // ENSGT00530000063823_1_Domain_4 (824, 847)

TCFECDITFNNVNNFYV
HKRLYCSGRRPPDXXXXXXXXXXXXXXXXXXXXXX-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

-----------------------------------------------------MP--KGP
H-SSPRA--VSTGSPGDMDAAEEAQAPDTS-LEEQETPAPEPMAIGRHEPLSPSSAVA--
-------PAHLESPGASE-EMEGPE------------PETQPREEAASPW--------SG
PEELELELR-DGRMC------------------MRARLSLAEGLSWGPFHGSIQPRASSP
----GQAE-PGPALTLLLTDQACWLKTLPQAPTEADANAEIY--RKDDSLWCRITRPVPA
GEALCVLLT-AEPQDTPSCPVKE-EPAEPKSP--APVLPDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGASSPATTAAEDKPKEPYPNERI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTSHMVCQPGSKGEIYSPGSAHPAAMLPTGEQPRGAWA
P-----------------------------------------------------------
HSRHAVHSPRCPPPRGQ-------------------------------------------
------------------------------------------------------SPRPES
W---QWPAR---------------------------CFCRSSCSRP-DGGAASGPTAPQA
SEILAKMSELVHSRLQQGAG--------PPAALLTGT---KGATCFECEITFNNVNNFYV
HKRLYCSGRRAPEDAPAARRPKATP--GTPS--------EPEAPRSPPGPG------VRE
DDTGGSVT--------------PEAEAPGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAAAPAPGP---VAPPLTTPPVRTR-RRRKLYE
LHPPGHAPTPSSHAPPAA-GHAPAAEPPVSPQPGSGSGSAGP------------APARSP
APAAADGPIDLSKRPRRQPPDA---------PAALPALADYHECTACRVSFHSLEAYLTH
KQYACPAAPLRPA-----------------------------------------------
------------------------AVCPYCPSNGRARGDLVEHLRRVHGLRGPAPRAPAE
RAPRGSPP------------------------------------PR--------------
-------SPS--PPP---------------------APAEAPADPGAPTP-------GKG
PPAIGGYR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------W--------SG
ADELEPVLQ-DDR------QWC-----------VRARRGLAEGFTWGPFRGSIQSRALSP
----RQAQ-PSPPLTLQLEDEVCWLRTLPQAESEAEANSLIY--RKDEALWCRTTKPVPA
GALLSMRLV-AESHSAPSPPRKR-EPGEAEGQ--APVHTDIQLLPQQAGMASILAT--AV
INKDIFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPAVAATEEKPKEAYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCRKSCPSASSLEIHMRS

ENSGT00530000063823_1_Linker_1_3 (443, 449)

HSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTSHMICQPGSKGELYSPGAGFPAAKPPADSLANFPH-
------------------------------------------------------------
--HAVLHGALATADLAPTL---------SPGLERKPHAEATNGEAWAAPQ----------
NGGEPPVIPRNIKV----EAEEEPE--------------VSKASSPTP-RAPSRTPSPRS
P----PVVQVKAERSSPSPACSPAPGELG--TPAGPLFLPQFVLGADA--------VPQA
SEILAKMSELVHSRLKQGQG---------APGLFAGAPAPKGATCFECEITFNNINNYYV
HKRLYCSGRHLAEDAPGVRRPKGP------------LSA-PAGNLRSPXQAPRRQ--RAR
A-----------------------------------------------------------
-----------------------------------------------------DAGKLYE
LHAPSAPPPPAPG------HAH--------PSPSRAARVAAPQ------KQEVGRA-LSP
GADAADGPIDLSKKPRRLGTEGP----PVPAAPGPLPLADYHECTACRVSFHSLEAYLAH
KKFSCPAAQLRGL-----------------------------------------------
---------------------RAPDVCPYCPPNGLVRGDLLEHLRRAHGLLVGQPQRSGS
-----------------------------------------------VAAPAD-------
--------------------------------------DPCPLGQGQQT----PG--KGP
PVPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAKEEAQAADTS-LPEQEATALEPEPTSPSS------PEANP
PPPPL--SPAPTSPGCP------EEPE--H---REP-EMMPEEEAASSPW--------SG
PDELEPLLQ-DGQRC------------------VRARCSLTEGLSWGPFRGSIQTRASSP
----GQAE-LSPALTLLLEDEACWLRTLPQPLAEAEANAEIY--RKDEALWCRLTRPVPA
GGQLKVLLV-AKPPSNPSHPVKK-EPAEPESP--APSHPDIQLLPQQAGMASILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPAVAALDEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLTGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGAKAEIYSPGTGHLTAKLPADSLAAF---
------------------------------------------------------------
QQHTALHSPLASADLGLAPAP-------SPGVDRKALAEATNGEARVGPQNG--------
GDGEPLAAPRSIKV----EAAEEPE------------------AEPGP-LAPSRTPSPPS
P----GPARVKAELSSPTPGSSPGPSA---------LFLPHL------------PAAPPA
SEILAKMSELVHSRLQAGAGVG------APAGLFAGA--PKGATCFECDITFNNVNNFYV
HKRLYCSGRRPPDDAPPARRPKAA--PAPPRVPPAPPSAEAEAPRSSPGPG------ARE
DEAGSTAT------------PEAEADASGRGSEGSPSPGSGA-DEDDDPRRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAPA---------GTPAPSAPPVRTR-RRRKLYE
LHAAGPAPPL-AG------PAPPLAGPAPPSAPGPAPTPPGPAP----TPPASPRPGSGS
GPDAPEGPIDLSKKPRRQAPAATPG-----PAPGLATLADYHECTACRVSFHSLEAYLAH
KKFSCPAAPRRLRA----------------------------------------------
-----------------APEDPPAVVCPYCPPNGVVRGDLIEHFRLAHGLLLGKPLVGPG
AEARTPSP----------------------------AAPRDGLNGQDLQEPPA-------
------SSPRPGPPPAA------------SPEAVAVPAPPSHSDKGVQTP--SQG--APA
PVPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-------------------------------------------------------MSRRK
Q-SNPR---QIKRSLRDMEAREEAQAADTG-LPEREATALEPEPPSPSGPXXXXXXX---
-------XXXXXXXGGSE-ETEGPE-----------PETRLEEEEPSSPW--------SG
PXXXXXXXXXXXXXXXXXXXXX---------------XXXXXXXXXX---XX--XXXXXX
----XXXXXXXXXXXXXXXXXXXXXXTLPRALTAAEANSEIY--RKDGALWCRLTRPVAA
GGRLSVLLA-AEPHSAPSQPVK--EPVEPEGLAPSP-AADIQLLPQQAGMASILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGTSSPAVAAPDEKPKETYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCRKSCPSASSLEIHMRS

ENSGT00530000063823_1_Linker_1_3 (443, 449)

HSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTLTXXXX
X------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXXXXXX--------------------------XX---XXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXX-------
XXXXXXXXXXXXXX----XXXXXXXX-X-----------XX--XXXXX-XXXXXXXXXXX
X----XXXXXXXXXXX-------X--XXX---XXXXXXXXXXXXXXXX------XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXX--XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXX----XX-----X------XXXX-XXX------XXX
XXXXXXXX---------------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXHRYYCAS-RHDPPPRRPAPPGP-------PGPAPAAPPVRTR-RRRKLYE
LHVSGPAPSPPPP------GHAPTPPASPAPRPGSGN------------------GGGGG
SPRPAEGPIDLSKKPRRQAPAA-----------PAPALADYHECTACRVSFHSLEAYLAH
KKFSCPSAPRRLRA----------------------------------------------
-----------------APEDPPAIVCPYCPPNGVVRGDLIEHFRLAHGLLLGKPPAGSG
PGAEARTP---------------------------SPRPRDGLNGQDPWEPPP-------
-----------GP-------------APPATSPEAVPAPPSHSDKGVQTP--SQG--TPA
SVPNGNHRYCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAGEEAKAMDSS-PKEQEAPAPEAPAIEEP----PSPPREDV
SPPAV--PAPPESPEDPE-DMEGQELE--MRPQDEEKEEKEEETAMASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFYGSIQTRAISP
----EREE-PGPAVTL-MVDESCWLRMLPQVLTEEEANSEIY--RKDDALWCRVTKVVPS
GGLLHVRLV-TEPHGAPRHPVQEPVE--PGGS--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPV-SATEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLAPDSLAGF---
------------------------------------------------------------
QQHSLMHSPLVPADKV---------PTPSSGLDSKALAEVTNGETRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEATR-----------ASGPGEP-GPQAPSRTPSPHS
P----NTVRVKTELSSPTPGSSPGPGELT---MAGTLFLPQYVFSPDAGT-TTVPTAPQA
SEILAKMSELVHNRLQQGAGSSGAAG--TPTGLFPGS---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDPPTVRRPKAAP--GPARAPVGAA-AEPDPSRTSPGPG------ARE
EEASGTTT--------------PEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAPTPAPGP---AAPALTAPPVRTR-RRRKLYE
LP-IAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSA--SAGP-------------APALS
PSPVPDGPIDLSKRPRRQSPDA---------PTALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTT-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPG
AEPRTPAERA----------------------------PRDSPDGRAPRSPS--------
--------------------------------PAPENTPSDPADQGVRTPSKGPPAPAPA
SSGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAGEEAKAMDSS-PKEQEAPDPEAPAIEEP----PSPPREDV
SPPAV--PAPPESPEDPE-DMEGQELE--MRPQDEEKEEKEEEAAMASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFYGSIQTRALSP
----EREE-PGPAVTL-MVDESCWLRMLPQVLTEEAANSEIY--RKDDALWCRVTKVVPS
GGLLYVRLV-TEPHGAPRHPVQEPVE--PGGL--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPV-SATEEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGF---
------------------------------------------------------------
QQHSLMHSPLVPADKA---------PTPSSGLDSK--AEVTNGETRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEATR-----------ASGPGEP-GPQAPSRTPSPHS
P----NPVRVKTELSSPTPGSSPGPGELT---MAGTLFLPQYVFSPDAGT-TTVPTAPQA
SEILAKMSELVHNRLQQGAGSSGAAG--TPTGLFSGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDPPTVRRPKAAT--GPARAPAGAA-AEPDPSRSSPGPG------PRE
EEASGTTT--------------PEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAPTTAPGP---AAPALTAPPVRTR-RRRKLYE
LP-AAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSA--SAGP-------------APALS
PSPVPDGPIDLSKRPRRQSPDA---------PTALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTT-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPG
AEPRTPAERA----------------------------PRDSPDGRAPRSPS--------
--------------------------------PAPENTPSDPADQGARTPSKGPPAPAPA
PGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
ADELELVVQ-DGE-------RR-----------VRARQSLPEGFSWGPFQGSIHSEPASP
----GHGEAQSPPVTLVLGDESCWLSRLPLVPGDARCQHCHL--QEDDAVWCRTTRAVQE
DEPMCAFVV-AEPAAIPRQAVKA-EPGDSPYP--AALHSDIQLLPQQAGMAAILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLMYYCAS----RQSA--GS-PAVDEKPKETYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCKKSCPSASSLEIHMRS

ENSGT00530000063823_1_Linker_1_3 (443, 449)

HSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTLNGVCH
S------CGFISTTRDILYSHLVTNHMICQPGSKGEVYSPGPALPAAKPLTPGLSQPNNA
P-----------------------------------------VLKCSLPAFIPEGLPALP
QHMV-LHGPLPTVLPGPDATPQPASP--SDTTTGPTSSEAQNGEVPREGQS---------
SSG----EPIRIKE----EPADSPAGSEAEEPK-SREAAASPSSEPEP-SS--RTSSPRS
L----PPGKVKSELASPTPGSSPVPSEPGSGTAGGTVFLPQYLFGHEAA-----AVVPQA
SEILAKMSELVHSRLKQGHG---T----VPPGLFTGAPVPKGATCFECEITFNNINNYYV
HKRLYCSSRHLAEDSPPGA-RKLKVPPAAPKGPPVPG------TLLSAPSGEGQSAPSAD
GEVGRAATPPAPLEEGKAVSPGTEVAASGRCSEDSQSPV--SSEGDEDPSKTLCEACNIR
FSRHETYAVHKRFYCAS-RHDPPLRR----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

-----------------------------------------------------MS--RRK
Q-SNPR---QIRRSPGDMEVLEEAQAPDTS-LQEKETPTPEPTA-----PLSPSSRDVNP
PPAPTVP---------TP-EMEGPEPE------------MQPLEETASPW--------SG
PEELQLELR-DGRSC------------------VQARLSLDEGLSWGPFHGSIQARASTP
----GQAE-QGPALTLLLTDKACWLRTLPQALTEADANSEIY--RKDDGLWCRITRPVPA
GGALCVRLT-VEPRGTPSCPVKE-EPNS---P--GQMHPDIQLLPQQAGMASILAT--AV
INKDIFPCKDCGIWYRSERNLQAHLLYYCAS----RQGASSPATTATEDKPKEPYPNERI

PF00096 // ENSGT00530000063823_1_Domain_1 (421, 443)

CPFPQCRKSCPSASSLEIHMRSHSGELHA---------QPGSPCPQHRALYTPTAEGVCH
S------CGFISTTRDILYSHLVTSHMVCQPGSKGEIYSSGAAHPAAKLPPDTLSSL---
------------------------------------------------------------
QQHAALHGPLPSADLGLATTP-------SPALDRKALVEATNGEARAAPQNG--------
SGGDSPTVPRSVKV----EAEKEAEAVR-----------TPGRAEPAT-RAPSRTPSPHS
P----GANCVKAELPSPTPGASPAPGELA---LASTLFLPQLVFAPDAGA-TPGPAAPQA
SEILAKMSELVHSRLQQGTG--------PPAALLAGT---KGATCFECEITFNNVNNYYV
HKRLYCSGRRAPEDAPATRKPKAP---------PG-APAEPDAPRSPPGPG------AGE
DETGGAVT--------------PEAEGPGRSSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPVTAPAPGS---AAPALTTPPARTR-RRRKLYE
LHAPGSAPAPPSHAP--------VAEPPASPGPGSASANAGPA------------PARSP
APPAADGPIDLSKRPRRQTPDR---------SAPLPALADYHECTACRVSFHSLEAYLAH
KQYACPAAPLRPA-----------------------------------------------
------------------------AVCPYCPANGRARGDLVEHLRRAHGLRGPAPRAPAE
HAPR------------------------------------DSPPPRSPSP----------
----------------------------------PPQSSEAPADPGAPAP--GKG--PPA
APAPGSHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-------------SLGDMEAGEEVPLVGAS-HVEQKATAPE----------ALSPPSADV
NSPPP--LPPPTSPGGPQ-EL----EE--QEP-----EPRPTEEEPGSPW--------SG
PDELEPVVQ-DGQRR------------------IRARLSLATGLSWGPFHGSVQTRASSP
----GQAE-PSPALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AKPRSTPGHPVEKEEPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INR---------------------------------------------------------
-------------------------ERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTALHGPLASADLGLAPTP-------SPGLDRKALAEATNGEARAAP--Q------NG
GSSEPPAAPRSIKV----EAVE-EPEAA----------PIPGPGEPGP-QVPSRTPSPRS
P----APARVKAELSSPTPGSSPVPGELG---LAGALFLPQYVFGPDG--------APPA
SEILVKMSXXXXXXXXXXXXXXX-------------------XXXXXXXXXXXXXXXXXX
HKRLYCSGRRAPEDAPAARRPKAP--PGPARAPPGPP-AEPDAPRSSPGPG------ARE
DGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAAPPGPP-GPAAPPAPAPAAPVRTR-RRRKLYE
LH-AAGAPPL--------------------PPPGHAPAPESPRPGSG--SGPGPAP-ARS
PDPAADGPIDLSKKPRRPLPGA-----------PAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PAPAASPQPGSRGLRDGLGPEPQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAREEVQLVGAS-HMEQKATAPE----------APSPPSADV
NSPPP--LPPPTSPGGPK-EL----EG--QEP-----EPRPTEEEPGSPW--------SG
PDELEPVVQ-DGQRR------------------IRARLSLATGLSWGPFHGSVQTRASSP
----RQAE-PSPALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPHSTPGHPVKK-EPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGTGSPAAAATDEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTALQGPLASADLGLAPTP-------SPGLDRKALAEATNGEARAEPLAQ------NG
GSSEPPAAPRSIKV----EAVE-EPEAA----------PILGPGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPGSSPVPGELG---LAGALFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAGAGAGG---AQTGLFPGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARRPKAP--PGPARAPPGQP-AEPDAPRSSPGPG------ARE
EGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAAPPG-PPGPAAPPAPSPAAPVRTR-RRRKLYE
LH-AAGAPPP--------------------PPPGHAPAPESPRPGSGSGSGPGLAP-ARS
PGPAADGPIDLSKKPRRPLPGA-----------PAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PAPAASPQPGSRGPRDGLGPEPQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-------------SPGDMDTAEGAQAPDTS-LEEQEALAPEPTAVGRPEPLSPSTADVNP
PLAPSPAPAHPTSLGAPE-EMEGPGPE------------TR-QEEAASPW--------AG
PEELELELR-DGQRR------------------VQARLSLAEGLCWGPFHGSIQTRAAPP
----GLTE-PSPALTLLLTDKACWLRTLPQALTEADANSEIY--RKGDSLWCRVTRLVPP
GEALRVLLT-AEPRGTPSHPMKE-EPAEPENP--APAPPDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLFYYCAS----RQGASSPAAAATEDKPKEPYPNERI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTSHMVCQPGSKGEIYSPNAAHPAAKLPADTLAGL---
------------------------------------------------------------
QQHPGLHGPLASSDLGLAPIP-------SPGLDKKALVEATNGEA----QNG--------
SGSEPSTVPKSVKV----EAAEESEAAR-----------VPGQVEPAP-RAPSRTPSPHS
P----SETRVKAEMPSPTPDGVPTPGKGL-------------------------------
-----------------------------PAPV-APG---GHR

PF12874 // ENSGT00530000063823_1_Domain_4 (824, 842)

YCRLCNIRFSSLSTFIA
HKKYYCSSHAAEHVK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMESGEEVRAADAG-LAEREAAAPEPRSPCS----------PDV
KSPPP--P--PPPT-SPG---APEETE--G---TEPRPQEEEEEELGSPW--------SG
PDELEPVLR-DGQ-------RR-----------VRARRSLAAGLSWGPFAGNVQTGASSP
----RQAE-PSPALTLLLADQACWLSTLPRALTPAEANAEIY--RKDDALWCRVTKPVPA
GVLLSVLLT-AEPGGAPSHPVKQ-EPAEPACPAPAPAHSDIQLLPQQAGMASILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQSAGSPATAAADEKPKETYPNERI

PF00096 // ENSGT00530000063823_1_Domain_1 (421, 443)

CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGF---
------------------------------------------------------------
QQLPALHGPLASTDLGLAPAL-------SPGLDRKAVAEATNGVAPQNGSSSES------
-----PAAPRSIKV----EAAEEP-----EV-------ARAAPGEPGP-QAPSRTPSPRS
P----APVRVKAELSSPTPGSSPVPGELG---LAGALFLPQYVFGPDA-----------A
SEILAKMSELVHSRLQQGAA---G----AQPGLFAGT--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRVPEDAPAARRPKAA--PVPARAPPGPPPE-PDAARSSPGPG------ARE
EGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDADDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAPP---------AP-------------PPRLYE
LHAASRPSRGPPG------RHG-------------------------RAAQAAAGP-RLS
ARPAADGPIDLSKKPRRSPTRP--AAPSTPRSRP------HFACARLRRA----------
-------LPLADPG--------------AEARH--------QPSAGRRR--------SPP
LPVATA------------------------PAA-----------RAAAG-----------
------RPAEPRAA---------------------------ASPGHQPAAP---------
--G------R-----------------SAVAAHTTGRSPPPSGDKGVQTP--GKA--APA
PVPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-----------------MEAGEEMQLVGTS-HTEQKAMAPE----------APSPPSTDV
SSPPP--PPTPTSPGGPK-EL----EG--QEP-----EPRPTEEEPGSPW--------SG
PDELEPVVQ-DGQRR------------------VRARLSLAMGLSWGPFHGSVQTGASSP
GQAADGPL-PTSALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPRSTPGHPVKK-EPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPATAAADEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTTLHGPLASADLGLAPTP-------SPGLDRKALAEATNGEARAAP--Q------NG
GSSGPPAAPRSIKL----EAVE-EPEAA----------RAPGTGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPVSSPVPGELS---LAGALFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAGAGAGG---AQTGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARR----------------------------------------
----------------------PKDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYSVHKRYYCAS-RHDPPPRR----------------------------------
------------------------------------------------------------
--PAADGPIDLSKKPRRPPAGA-----------SAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPX
XXXXXXXXXXXXXX-----------XX-XXXXXXXXXXXXXXXXXELQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-----------RDCLVLLVQGKP----------------------------AAGPPEPTC
CHDPG--R--HCSEGCTQ-ILLPSVPG--E---TESRRAGSGQQQAVRPRAGQ----GSG
PSQGSRQLQ-ERVRCYPISRWKAKPHSLATPGTVEPVSGRPSGSPWM-------TEPIHP
------CSPQGPALTLLLVDEACWLRTLPQAPTEAEANAEIH--RKDDTLWCRVTKPVPA
GGLLHVFLM-AEPRG---HPVKK-EPAEPECP--APVPTDIQLLPQQAGMASILAS--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQSAGSPATAATEEKPKESYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDGLASI---
------------------------------------------------------------
QQHSAPHGPRASGDLGLAPAP-------SPGQDRKVLAEATNGEARVAPQNG--------
GGSETPAAPRSIKV----EAVEEPEAAR-----------APGPGEPGA-QALSRTPSPHS
P----AAARVKAELSSPTPGSSPGPGELG---LAGALFLPHYVFGPDAGAP---SGAPQA
SEILAKMSELVHSRLQQGAGVAG-----TPAGLFAGA---KGATCFECEITFNNVNNFYV
HKRLYCSGRRPPEDTPAARRPKTI--PGPPRATPGPPAE-PEATRSSPGPG------TRE
DDAGDAAT--------------PEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAP---PSA---LDSP-----------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------E----------------
------------------------------------------------G-----------
------------------------------------RAPRSPSP---PAPNAD-------
-----------------------------------------PADLGTTTP--SK---GPP
APAASSHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGAMEEGEDAAAGEQS-PMERDGTTSEREGS----------AECDA
CSPPS--S--EEVE-CKD---VPESPK--E---TE-KSDPGENTQELSSW--------NG
PDELELVVQ-DGE-------RR-----------VRARQSLPEGFSWGPFQGSIHSEPTSP
----GHGEAQSPPVTLVLGDESCWLSCLPLVSGEPDANAVIY--RKDDAVWCRTTRAVRE
DEPMCAFVV-AEPAAISGQAVKA-EPGDSPYP--AALHSDIQLLPQQAGMAAILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLMYYCAS----RQSA--GS-PAVDEKPKETYPNERV
CPFPQCKKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLNGVCH
S------CGFISTTRDILYSHLVTNHMICQPGSKGEVYSPGPALPAAKPLTPGLSQPNNA
P-----------------------------------------VLKCSLPAFIPDGLPALP
QHVV-LHGPLPTVLPGPDATPQPASP--SDTTTGPTSTEAQNGETPGEGQSSS-------
SSG----EAIRIKE----EPADSPAGSEAEEPK-SGEAAGSPSSEPEP-SS--RTSSPRS
L----PPGKVKLELASPTPGSSPVPSEPGSGTAGGTVFLPQYLFGHEAA-----AVVPQA
SEILAKMSELVHSRLKQGHG---A----VPPALFTGAPVPKGATCFECEITFNNINNYYV
HKRLYCSSRHLAEDSPPGA-RKLKVPPAAPKGPPGAG------TLLSAPSGEGQRAPSGD
GDVGRAATPPAPLEESKAVSPEAEVAASGRCSEDSQSPV--SSEGDEDPSKTLCEACNIR
FSRHETYAVHKRFYCAS-RHDPPLRRPGLP----------KVPFVPQPLRTR-KRRKLYE
IHGAE-------------------PPPPPDP------------------KAPAAAP-SPS
SSPDAEGPIDLSKKPRRRGGE--------QNAATLLPFADYHECTACRLSFNSLDSYLAH
KKFSCPATPLQPGAMEHLQKIKGAVPKGHRDG----EGDKTAPAGTTKA-----L--PPA
YPAAT-----VGDSRYPKGAKGPLSVCPYCPLNGTIKGDLIEHFRHVHGLFVAAHGLPDA
PRPGGGRTPEPPAASPPRPPA----------P-R-LR-R-DSF-NGK-EA-RD-A-P-P-
N-G--S-P-R--P------------PVSPRPPTDKPPTPPSYTDRGVQTP-PAKA--APG
PVPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAGEEVLLAGAS-HVEQKAMAPE----------APSSPSTDV
NSPPP--PPPPTSPGGPE-EL----EG--QEP-----EPRPTEEEPRSPW--------TG
PGNHVVV--------------------------------------------------GLA
ASPPRQLG-PSPALTLLLVEESCWLRMLPQALTEAEANAEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPCSTPGHPVKK-ESAEPTCPVP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHWLYYCAS----RQGAGSPATATSEEKPKEAYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCHKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGSGQAATKLPPDSLGSLQ--
------------------------------------------------------------
-QHSALHGPLASTDLGLAPTP-------SPGLDRKALAEATNGEARVAP--H------NG
GSSEPPAAPRSIKV----EAGE-EQEAT----------RAPGPGESGP-HAPSRTPSPRS
P----VPAKAKAELSSPTPGSSPVPGELG---LAGALFLPPYVFGSDS--------APPA
PTILAKMSELVHSRLQQGAG--------AQAGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARRPKAP--PGPARAPPGPP-AEPDAPRSSPGPG------TRE
DGAGGATT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAAPPGPAAPP-------PAAPVRTR-RRRKLYE
LHAAAGAPPR--------------------PPPGHAPAPESPRPGSGSGSG--PAP-TRS
PGPAADGPIDLSKKPRRQPPGA-----------PAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PVPAASPQPGPRGSRDGLGPEPQEPPSG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--APA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------MGLGCCC--HPC
P-GTSG---PQGGSPGDMDAAEEAQAPDSS-LEEQEAPAPEPTAIGRPEPLTPSTADVNP
PLAPA--PVHSTSPGAPE-EMEVPGPE------------TL-REEATSPW--------SG
PEELELELR-DGQRC------------------VQARLSLAKGLCWGPFRGSIQTRAPSP
----GQAE-PGPALTLLLTDAACWLRTLPQALTEADANSEIY--RKDGSLWCRVTRPVPA
GEALCALLT-AKPRGTPSHPTKE-EPAEPENP--APVPPDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRNERNLQAHLLYYCAS----RQGASSPAAAATEDKPKEPYPNERI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTSHMVCQPGSKGEIYSPGAAHPAAKLPADALASL---
------------------------------------------------------------
QKHAGLHGPLASADLGLAPIP-------SPGLDK-TLVEATNGEA----QNG--------
SGGETPAIPKNVKV----EAAEESEAAR-----------VPGQAEPAP-RAPSRTPSPHS
P----GAARVKAEMPSPTPGASPAPGELG---LAGALFLPQLVFAPDAGA-APGPAAPQA
SEILAKMSELVHSRLQQGAG--------APAALLAGT---KGATCFECEITFNNVNNFYV
HKRLYCSGRRPPEDAPAARRPKAP---------PGGAPAEPDAPRSPPAPG------ARE
DEAGGAAT--------------PEADGPGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAPAPAPGS---AAPTLTTPPVRTR-RRRKLYE
LHAPGSAPAPPGHGP---PAAGPAPEPPGSPGPGGGNGSAGPA------------PARSP
APAAADGPIDLSKRPRRQPHDA---------PAALPALADYHECTACRVSFHSLEAYLAH
KQYACPAAPLRPA-----------------------------------------------
------------------------AVCPYCPANGRARGDLGEHLRRAHGLR---------
----------------------------------------DSPPPRSPSP----------
----------------------------------PPAPAEAPADPGAPTP--GKG--PPA
PPTPGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-------------SLRDMEAREETQAMGIS-PMEQEATSPEAPAIEES----PSPPREDV
SPSTV--PAPPESPEGPE-DMEGQELE--MGPQDEEKEEKEEEAAIASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFHGSIQTRALSP
----EREE-PGPAVTL-LVDEACWLRMLPQAQTEAEANSEIY--RKDDALWCRVTKVVPS
GGLLRVLLM-TEPGSTPRHPVKEP--VEPGGP--APAHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPA-SATEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGSGHPAAKLPPDSLASF---
------------------------------------------------------------
QQHSLMHGTLAPADKA---------PTPSSGLDSKALAEVTNGESRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEATR-----------ASGPGEP-GPQAPSRTPSPHS
P----TPVRVKTELSSPTPGSSPGPGELA---MAGTLFLPQYVFGPDAGN-TTGPAAPQA
SEILAKMSELVHSRLQQGAGSSGAVG--TPTGLFPGT---KGATCFECEITFNNINNFYV
HKRLYCSGRP--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------ATLPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTA-----------------------------------------------
------------------------ALCPYCPPNGHVRGDLVEHLRLVHGLQVAKPAANPG
AEPRTPAERA----------------------------PRDSPDSRAPRTPS--------
--------------------------------PVPENTPSDPTDQGVRTPSKGPPASAPA
SGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHASEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAGEEAKAMDSS-PKEQEAPDPEAPAIEEP----PSPPREDV
SPPAV--PAPLESPEDPE-DMEGQELE--MRPQDEEKEEKEEEAVMASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFYGSIQTRALSP
----EREE-RGPAVTL-MVDESCWLRMLPQVLTEEAANSEIY--RKDDALWCRVTKVVPS
GGLLHVRLV-TEPHGAPRHPVQEPVE--PGGL--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPV-SATEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGF---
------------------------------------------------------------
QQHSLMHSPLVPADKV---------PTPSSGLDSKALAEVTNGETRVPPQNG--------
GNSESPAAPRTIKV----EAAEEPEATR-----------ASGPGEP-GPQAPSRTPSPHS
P----NPVRVKTELSSPTPGSSPGPGELT---MAGTLFLPQYVFSPDAGT-TTVPTAPQA
SEILAKMSELVHNRLQQGAGSSSAAG--TPTGLFSGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDPPTVRRPKAAT--GPARAPAGAA-AEPDPSRSSPGPG------ARE
EEASGTTT--------------PEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAPTTAPGP---AAPALTAPPVRTR-RRRKLYE
LP-AAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSA--SAGP-------------APALS
PSPVPDGPIDLSKRPRRQSPDA---------PTALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTT-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPG
AEPRTPAERA----------------------------PRDSPDGRAPRSPS--------
--------------------------------PAPEKTPSDPADQGARTPSKGPPAP--A
PGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAGEEVPLAGAS-HVEQKATAPE----------APSPPSTDV
NSPLP--PPPPTSPGGPE-EL----EG--QEP-----EPRPREEEPRSPW--------TG
PDELEPVVQ-HGQRR------------------VRARLSLTTGLSWGPFHGSVQTRASSP
----GQAE-PSPALTLLLVDESCWLRTLPQALTEAEANAEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPRSTPGHPVKK-ESAEPTCPVP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSLATAASEEKPKEAYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCHKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGQAATKLPPDSLGSLQ--
------------------------------------------------------------
-QHSALHGPLASTDLGLAPTP-------SPGLDRKALAEATNGEARAAP--H------NG
GSSEPPAAPRSSIK----VEAAEEPEAA----------RAPGPGESGP-HAPSRTPSPHS
P----ASAKAKAELSSPTPGSSPVPSELG---LTGALFLPPYVFGSDA--------APPA
SEILAKMSELVHSRLQQGAG--AGG---AQAGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARRSKAP--PGPARAPPGPP-AEPDAPRSSPGPG------ARE
DGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAAPPGPA-PPPPPAAAAPAAPVRTRRRR-KLYE
LHAAAGAPPR--------------------PPPGHAPAPESPRPGSGSGSG--PAP-TRS
PGPAADGPIDLSKKPRRQPAGA-----------PAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PVPAASPQPGPRGPRDGLGPEPQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--APA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-------------SLGDMEAGEEAQVVNTS-FTEREATAPEPPSPSTRXXXXXXXXXXXX
---------------------X-XXXX----------XXXXXXXXXXXXXXXXXXXXXXX
XXELEPALQDDGQWC------------------VRARRGLAEGVTWGPFRGSVQSGASSP
----RQAQ-LSPALTLQLEDEACWLRTLPQAETEAEANLLIY--RKDEVLWCRTTKPVLV
GGLLSVHLM-TESHSAPTPPRKR-EPGEAEGQ--APAHTDIQLLPQQAGMASILAT--AV
INKDIFPCKDCGIWYRSERNLQAHLLYYCAS----RQSAGSPAVTATEEKPKEIYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLS-FTTKANCERHLKVHTD-LSGVCH
S------CGFISTTRDILYSHLVTSHMICQPGSKGELYSPGPGYQATKPPVDSLAGF---
------------------------------------------------------------
PQHTVLHGTLATTDLA---------PTPSPGLERKPLAEATNGDAWPQN-----------
-GSEPPAIPRSIKV----EVEEEPEVTRT--------------LSPA-PGAPSRTPSPRS
P----RVVQVKAEHSSPSPARSPTPGELG--APAGPLFLPQFVLGADA--------VPQA
SEILAKMSELVHSRLKQGQG----------AGLFAGAPASKGATCFECEITFNNINNYYV
HKRLYCSGRHQAEDTPGVRRSKSSAR---TRGPCCQ-PADPDAGRSPPSPE------ARE
EGSRGAAT--------------PEAEAASRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPATS-----------APAEPTPVRTR-RRRKLYE
VHAPGVPPQPAPGPTHS-----GQAEPPSSPHPGSGS--------------------VLR
PGLASDGPIDLSKKPRRQGPEG----------PGPVPLADYHECTACRMSFHSLEAYLAH
KKFSCPATQLRGLH----------------------------------------------
------------------SLPAAAVVCPYCPPNGLVRGDLLEHLRRAHRLLVGRPEVRTP
PAP---------------------------TASPPPRAPRDSLNGQELREPAA-------
------GSPRPGPPVSPATTP---------AALPPMPTPPAHSDKGVQTP--GKG--PLA
PVPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------MSRPAAPLPPAAARQGLEAAAARTRGAGDMS--RRK
Q-SNPR---QIKRSLRDMEAREETQAMGIS-PMEQEATSPEAPAIEES----PSPPREDV
SPSTV--PAPPESPEGPE-DMEGQELE--MGPQDEEKEEKEEEAAIASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFHGSIQTRALSP
----EREE-PGPAVTL-LVDEACWLRMLPQAQTEAEANSEIY--RKDDALWCRVTKVVPS
GGLLRVLLM-TEPGSTPRHPVKEP--VEPGGP--APAHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPA-SATEEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGSGHPAAKLPPDSLASF---
------------------------------------------------------------
QQHSLMHGTLAPADKA---------PTPSSGLDSKALAEVTNGESRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEATR-----------ASGPGEP-GPQAPSRTPSPHS
P----TPVRVKTELSSPTPGSSPGPGELA---MAGTLFLPQYVFGPDAGN-TTGPAAPQA
SEILAKMSELVHSRLQQGAGSSGAVG--TPTGLFPGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDTPSVRRPKAAP--GPARATPGA---EADPQRLSPGPG------PRE
-ETGGATT--------------PEAEAAGRGSEGSQSPGSSVDDTEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPSAPAPAPGP---AAPALTAPPVRTR-RRRKLYE
LP-GASAPPPAVGPAPVPVVPAPTAELPSSPRPASA--SAGP-------------TPTPS
PGPVPDGPIDLSKRPRRQTPDA---------PATLPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTA-----------------------------------------------
------------------------ALCPYCPPNGHVRGDLVEHLRLVHGLQVAKPAANPG
AEPRTPAERA----------------------------PRDSPDSRAPRTPS--------
--------------------------------PVPENTPSDPTDQGVRTPSKGPPASAPA
SGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHASEHVK-

------------------------------------------------------------
------------------------------------------QPLC--APESPSPPAQKC
HTPPP--LPQRTDPGGPR-AFSPGEPD--PRPLRQS----------A-------LSPTG-
-HPHHGMLQ-DGQRR------------------VRAQRSLTEGLSWGPFRGNVQSRASSP
----GQVE-PGPALTLLLEDESCWLRTLPQALTEAEANAEIY--RKDEALWCRLTKPVPA
GGLLSALLTAAEPRSTPSHPMKK-EPAEPECP--APAHADIQLLPQQAGMASILAT--AV
INKDVFPCRDCGIWYRSERNLRAHLRYYCAG----RQSTGSXXXAAADEKPKETYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCRKSCPSASSLEIHMRS

ENSGT00530000063823_1_Linker_1_3 (443, 449)

HSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTSHMVCQPGSKAEIYSPGASHPTAKLPPDSLASF---
------------------------------------------------------------
QQHTALHGPLASADLGLAPTP-------SPGLDRKALAEATNGEAKPAPQNG--------
GSSEPPAAPRPIKT----EAATEESE-----------------AEPGP-LTASRTPSPCS
P----APARVKAELSSPTPASSPGPGELG--LAAGALFLPQF------------PAAPPA
SEILAKMSELVHSRLQAGAG--------AQAGLFAGA--PKGATCFECDITFNNVNNFYV
HKRLYCSGRRPPDXXPSTRGLGAPA--GPARSPRS-RRALTQARPGSPGPGSASPWL-GG
RGAGQ-----------------VRLWAGGPGGSGRP------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------SLGDMETSEETQATDTS-LTEHDTTQPEPPSP----------PRADA
ALSPP--PAPPTSPGAPKEEMEGPEPE-------------ATSPTESNSW--------TG
PDELESVLC-SGQQQ------------------VRARDGLTRGLAWGPFQGSIKAMASSP
----RQAE-LDRALPLLVVDETCWLKMLPQALTQAEANCEIS--RKXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-----XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGSGSPA-TAAAEKPKEPYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RI
CPFPQCRKSCPSASSLEIHLRSHSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----X
X--------------XXXXXXXXXXX--------------------------XXXXX---
------------------------------------------------------------
XXXX-X--XX-----------------------X-XXX---XX--------X--------
-------XXXXXXX-----XX----------------------X---X-X--------XX
X----XXXXVHS--------------DL---AMVGALSLSQQELGADS--------ASHT
SEILSKMSELVHGRLQTGAAGGGPA----------G--TTQGATCFECDITFNSLSNFLV
HKRLYCSGRRAPEDPPARRKAPPRA------------PPEPDAPRSPPGPG------ARE
DEAGGAAT--------------PEADTADRGSEGSQSPGSSVDEADDDPSRTLCRPCNIR
FSRHETYTVHKRYYCA--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

-------------------------------------------------------MSRRK
Q-SNPR---QIKRSLGDMEEGEDNQAEDAS-QSEREGGASDPEAPSPPCSX---------
---XX-----------XX-XXXXXXXXXXX---X---XXXXXXXXXXXXXXXXXXXXXXX
XXELELISQ-DGENK------------------VRAKRNLPEGISWGPFSGNIQSEGSSP
----GQTE-TNPPMTLLVGEEHCWLTKLPLVSNETDANSVIF--RKDEAIWCKTTKPVPE
AGLMNAFVM-AEPRGITSNPVKA-EPGDPEYP--ATMHSDIQLLPQQAGMAAILAT--AV
VNKDIFPCKDCGIWYRSERNLQAHLMYYCAS----RQSSGSP---LVEEKPKETYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCKKSCPSASSLEIHMRSHSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X------XXXXXXXXXXXXXXXXXXXXXXXX-------------------XXXXXXX---
-----------------------------------------XXXXXXXXXXXXXXSLASL
QQHMALHGPLPTPDPSQAPTS------PPDTLVKKAPAEAENGDTQAEPLGGSATA----
----------RIKE-----EVGEGQGQEPEMVKSHS-------PRGSEPESSSRTSSPQS
L----ASVKVKSELASPTPGSSPVPSEAGVGPSGGTIFLPQYMFGPET------SVVPQA
SEILAKMSELVHSRLKQGHGGVAG--------PVP--RDPKGATCFECEITFSNINNYYV
HKRLYCSSRHVAEGSPPGARKPKVA--GPPKGP-GPG-SHPTRAVLSPQPPDARAHXXXX
XXXXXXXX--------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X-X---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXX-XX-----------------X---XXXXXXXXXXXXXXXXXGSHVAPSPS
SSPDTDGPIDLSKKPRLHKTEGAPT-------APPPPLTDYHECTACCVSFHSLEAYLAH
KKYYCPAAPLPKA-----------------------------------------------
-------------------LHLPASACPYCPLNGAIKGDLIEHFRHAHGLLVAKPVAGHI
LAEATTPHPRTPAENSL-----SPVTAPTASPQPGPRLPRDSFNGHELKESPPG------
------------LPLS---------PATVPEALLQPPTPPMYTDKGVQTP--SKV--APA
TVPNGNHRYCRLCNIKFSSLSTFI-----------------

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAGEEVQAVDTS-LMEQEAASPDPPVIEELP----SPPKADV
TPPPA--PAPPVSPGGPK-DMDPQELK--MRPQEEEKEEEEEEAAVASPW--------SG
PEELEL-SQ-DGQRC------------------VRARLSLTEGLSWGPFHGSIQTRTSSP
----EQAE-PGPALTL-LVDEACWLRMLPQALTEAEANSEIY--RKDDALWCKVTKSIPA
SGLLRVLLV-AESHSTPSDPVK--EPVEPEGP--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRASSPA-SATEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLAGF---
------------------------------------------------------------
QQPASMHAPLAPADK---------APTPSSGLDKKGLAEATNGEARVAPQNG--------
GGSEPPATPRSIKV----EAAEEPEPAC-----------APGPGQPGL-QAPSRTPSPHS
P----PPVRVKAELSSPTPGSSPGPGELG---VAGTLFLPQYMFGPDAATA--SSAAPQA
SEILAKMSELVHSRLQQGTGGPGAAV--APAALFPGT---KGATCFECEITFNNVNNFYV
HKRLYCSGRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX-XXXXXXXXXXXX---------XXXXXXXXXXXXX-XXXXXXX
XXXXXXXX----------------------------XXXXXXXXXXXXXXXSAGPPPALS
PSSVPDGPIDLSKRPRRQTPDA---------PAALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTA-----------------------------------------------
------------------------APCPYCPPNGRVRGDLVEHLRLAHGLQVAKPAAGGN
APPD--------------------------------------------------------
-----------------------------------------PADQGARTPGKGPP--VPA
PGTGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAREETQAMDIS-PMEREATSPEAPAIEEP----PSPPREDM
NPSTV--PAPPGSPEGPE-DVEGQELE--MGPQDEEKEEEEEEAAIASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFHGSIQTRALSP
----EQEE-PGPAVTL-LVDEACWLRMLPQAQTEAEANSEIY--WKDDALWCRVTKVVPS
GGLLHVLLV-TEPHSTPRHPVKEP--VEPGGP--APAHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPA-SATEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGF---
------------------------------------------------------------
QQHSLMHGPLAPADKA---------PTPSSGLDSKALAEVTNGESRVPPQNG--------
GSSESPAAPRTIKV----EADEEPEATR-----------ASGLGEP-GPQAPSRTPSPHS
P----TPVRVKTELSSPTPGSSPGPGELA---MAGTLFLPQYVFGPDAGT-NTGPAAPQA
SEILAKMSELVHSRLQQGAGSSGAVG--TPTGLFPGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRVPEDTPAVRRPKAVP--GPARATAGAA-AEADLQRLSPGPG------ARE
EEAGGATT--------------PEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPSAPTPAPGS---AVPALTAPPVRTR-RRRKLYE
LP-GAGAPPPAVGPAPVPVVPAPTAELPASPRPASA--SAGP-------------APTPS
PGPVPDGPIDLSKRPRRQTPDA---------PATLPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTA-----------------------------------------------
------------------------ALCPYCPPNGHVRGDLVEHLRLAHGLQVAKPAANPG
VEPRTPVERA----------------------------PRDSPDSRAPRTPS--------
--------------------------------PVPDNTPSDPADQGVRTPSKGLPASAPA
SGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAGEEVQLVGAS-HTEQKAIAPE----------APSPPSADV
NSPPP--LPPPTSPGGPK-EL----EG--QEP-----EPRPTEEEPGSPW--------SG
PGNHAGG----GGSS------------------I-------------------ASRATPP
HVF-LPHP-QSPALTLLLVDESCWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPHSTPGHPVKK-EPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGTGSPAAAATDEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTALQGPLASADLGLAPTP-------SPGLDRKALAEATNGEARAAP--Q------NG
GSSEPPAAPRSIKV----EAVE-EPEAA----------PILGPGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPGSSPVPGELG---LAGTLFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAG--AGG---AQTGLFPGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARRPKAP--PGPARAPPGQP-AEPDAPRSSPGPG------ARE
DGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAA----------PPAPSPAAPVRTR-RRRKLYE
LH-AAGAPPP--------------------PPPGHAPAPESPRPGSGSGSGPGLAP-ARS
PGPAADGPIDLSKKPRRPLPGA-----------PAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PAPAASPQPGSRGPRDGLGPEPQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAGEEMQLVGTS-HTEQKATAPE----------APSPPSTDV
SSPPP--PPTPTSPGGPK-EL----EG--QEP-----EPRPTEEESGSPW--------SG
PDELEPVVQ-DGQRR------------------VRARLSLAMGLSWGPFHGSVQTGASSP
----GQVE-PSPALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPHSTPSRPVKK-EPAELTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPAAAAADEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTALHGPLASADLGLAPTP-------SPGLDTKALAEATNGEARAAP--Q------NG
GSSEPPAAPRSIKV----EAVE-EPEAA----------RAPGTGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPVSSPVPGELS---LAGALFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAGAGAGG---AQTGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDASAGADPRRP--SARPARPGWPP-AEPDAPRSSPGPG------ARE
DGRGRRGG--------------------RGKPEGSQSPG--------------SSACNIR
FSRHETYSVHKRYYSPR-ATTRRRAARRAARGTPAGRAPGPRPSPR-PLRTRQTPPSFTS
WH-AAGAPPP--------------------PPPGHAPAPESPRPGSG--SGPGTAP-ARS
PGPAADGPIDLSKKPRRPPPGA-----------SAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEPRTPADRGPSPA-----------PAPAASPQPEPRGPRDGLGPELQEPPSG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLRDMEAGEEAKAMDSS-PMEQEAPAPEAPAIEEP----PSPPREDV
SPPTV--PALPESPEDPE-DMEGQELE--M-PQDEEKEEKEEEAAMTRPW--------SG
PEELELVLQ-DGQRC------------------VRTRLSLTEGLSWGPFYGSIQTRALSP
----EREE-PGPAVTL-MVDESCWLRMLPQALTEEEANSEIY--RKDDALWCRVTKVVPS
GGLLHVLLV-TEPHGTPRHPVQEPVE--PGGS--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPV-SATEEKPKETYPNERI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGICH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGF---
------------------------------------------------------------
QQHSLMHSPLVPADKA---------PTPSPGLDSKTLAEVTNGETRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEAAR-----------ASGPGEP-GPQAPSRTPSPHS
P----NPVRVKTELSSPTPGSSPRPGELT---MAGTLFLPQYVLGPDAGT-TTVPTAPQA
SEILAKMSELVHNRLQQGAGSSGAAG--TPTGLFPGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDPPAVRRPKSAT--GPARAPAGAA-AEPDPSRTSPGPE------TRE
EEASGATT--------------PEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAPTPAPGP---AAPALTAPPVRTR-RRRKLYE
LP-AAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSA--SAGP-------------APAPS
PSPVPDGPIDLSKRPRRQSPDA---------PTALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTT-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPG
AEPRTPAERA----------------------------LRDSPDGRAPRSPS--------
--------------------------------PAPENTPSDPADQGARTSSKGPPAP--A
SGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------MWPNEPPRVGLQ------------S--RTP
PDSPGV---VSTGSLRDMEAGEEAQTMDSS-LAEWETTSPEPPATDEP--ESLSPSRADV
NPPPA--PAAPSPPGGPE-EMKRQESETETRPQEEEEVKEEVEVAAASPW--------SG
PEELELALQ-DGQRC------------------VRAQLSLTKGLSWGPFHGSIQTRALSP
----GQAE-PGPVLTL-LVDEACWLRMLPQALTEAESNLEIY--RKDDALWCRVTKPVPA
GGLLHVLLV-AEPRITPNHPVKEPAE--TEGP--APMHSDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRASSPA-TATEEKPKEAYPNERI
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLASF---
------------------------------------------------------------
QQLTVMQGPLALADKA---------PTPSPGLDKKALAEATNGEAKVAPQNG--------
GSSEPPAAPKSIKA----EAVEEPEAAR-----------APGSGDDGGSRAPSRTPSPPS
P----PPVRVKTELPSPTPGSSPGPGELA---LAGALFLPQYVLGPDTGA-APGPATPQA
SEILAKMSELVHSRLQQGAGGAGAAAAPAPTGLFTGT---KGATCFECEITFNNVNNFYV
HKRLYCSGRRASEDAPANRRPKASA--GPARAPPGTP-AEPDPPRSSPGPG------ARE
DEAGGALT--------------PETEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCLY-E-----------------------------------------
LPAVAGAPPPAVGHAPSSAGHAPTPELPASPRPASGSGSAGP-------------APALS
PDAVPEGPIDLSKRPRRQSPDA---------PAALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRAA-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRLAHGLQVAKPAASAG
AEPRASSERV----------------------------PRDSPDGRAPRSPS--------
--------------------------------PTPEASPPDPADQGARTPGKGPPAPA--
--PGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
------------------------------------------------------------
--------------------MLLDLS-----------GPQSPQEPRAQPW--------KV
PLPAKPP-----------------------------------SPTWPSSQAG-----GRS
MSR-MPHI-PSPALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPRSTPGHPVKK-EPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPAAAAADEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTTLHGPLASADLGLAPTP-------SPGLDRKALAEATNGEARAAP--Q------NG
GSSGPPAAPRSIKL----EAGRAEPARA----------RGPRAGPPKG-GAPSRTPSPRS
P----APARVKAELSSPTPVSSPVPGELS---LAGALFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAGAGAGG---AQTGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAARRPKAP--PGPARAPPGPP-AEPDAPRSSPGPG------ASE
DGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYSVHKRYYCAS-RHDPPPRRPAAPPGTP-GPAVPPAPAPVAPVRTR-RRRKLYE
LH-AAGAPPP--------------------PPPGHAPAPESPRPGSGSGSGPGTAP-ARS
PGPAADGPIDLSKKPRRPPAGA-----------SAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEARTPADRGPSPA-----------PAPAASPQPEPRGPRDGLGPELQEPPPG-------
------------PPPSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
-----------------MESREEVQATDAS-LAEREAAAPEPRSPSS----------ADV
KSPPP--P--PPPT-SPG---GPEETE--G---TEPGPREEEEEESGSPW--------SG
PDELEPVMQ-DGR-------KH-----------VRARLSLAAGLCWGPFAGNVQTRASSP
----RQAE-PSPALTLLLADEACWLRTLPQALTQAEANAEIY--RKDDALWCRVTKPVPA
GALLSVLLT-TEPCGIPSHPVKK-EPAEPACP--APAHSDIQLLPQQAGMASILAT--AV
VNKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQSVGSPAAAAADEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLASF---
------------------------------------------------------------
QQHPALHSPLASADLGLAPSL-------SPGLDRKAVAEATNGVVPQNGGSSES------
-----PAAPRSIKV----EAAEEPE-------------VARAPGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPGSSPVPGELG---LAGALFLPQYVFGTDA------GGAPPA
SEILAKMSELVHNRLQQGAG---G----AQAGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDAPAAHMGSHYVALLASSS----------------------------
-------------------------------------PPISVSQS-----------AEIT
G-----------------------------------------------------------
------------------------------------------------------------
----------------------------------------MSHCTWPKR---FLHVFL--
------------------------------------------------------------
---------------------------------------------DICTLSP--------
---------------------------------PPPPPPLWGVTPGRLRRDTGDC-----
-------SPRPGPPP------------------SPPPPPPSLSDKGVQTP--GKG--APV
PVPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------APQSPALTLLLEDEACWLRTLPRALTEAEANVEIH--RKDGALWCRLTKPVPA
GGLLSVLLA-AEPHSTPNHPVKK-EPAEPECL--ATSHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQSAGSPATAAADEKPKEPYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCRKSCPSASSLEIHMRS

ENSGT00530000063823_1_Linker_1_3 (443, 449)

HSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTQSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKAEIYSPGVGHPSAKLPPGEPQGPPLR
AGRGLVHETQEGQFGLGPRPPLPSPAQLSLPTLPLPQAGPAPALKCGPWGLPADSL-PGF
QQLTALHGPLASSDLGLGSTS---------------------------------------
----SPGLDRSIKV----EAAEEPE------------------AEPGPPAPSSRTPSPPS
S----APARVKAELPSPTPGSSPGPGA---------LFLPQF------------PAAPPA
SEILAKMSELVHSRLQVGVGA-------GAPGLLAGA--PKGATCFECDITFNNVSNFYV
HKRLYCSGRRAPDETGGRTRRGARP--RPTH-----------------------------
------------------------------------------------------------
-------------------------RPAA-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------LAAGAWPGRPLPLP-
-------------------------------------PAMDRI-------------GQEP
PTGPPDGSPRPGPP-------------------SAPPTRPSHSDKGVQTP--SKG--TPA
SLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSS--------

-----------------------------------------------------------K
Q-SNPR---QKKRSLGDMEAGEEAQATETG-LPQREAAAPKPLSP--------SSPEVNP
LPPPP--PXXXXXXXXXX-----XX-----------------XXXXXXXXXXXXXXXXXX
XXELEQVLQ-DGQKC------------------VQARHSLAEGLSWGPFRGSIQSRASSP
----GQAE-PSPALTLLLEDEACWLRTLPCALTEAEANAEIH--RKDEALWCRLTKPVPA
GGLLSVLLS-AELHSTPSHPVKK-EPAEPECL--APSHTDIQLLPQQAGMASILAT--AI
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQSASSPATAITDEKPKEPYPNERI
CPFPPCRESCPSASSLEIHMRSHSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKSEIYSSGAGHPAVKHPSESLAGF---
------------------------------------------------------------
QQHTALHGPLASAELGLAPTP-------SPGLDRKALAEATNGEARPQN--G--------
GSGEPLAVPRSIKV----EAAEEPE------------------VSQGPPQPPSRTPSPPS
P----APARVKTELPSPTPGSSPGPGA---------LFLPQF------------PAAPPA
SEILAKMSELVHSRLQAGVGAGAG----SPAGLLAGA--PKGATCFECDITFNNVSNFYV
HKRLYCSGRRAPDDAPPTRRPKAP--PAPARAPPAPPPAEPDAPSSSPGSG------ARE
DQAGDAAT--------------PDAEAGSRGSEGSPSPGSGA-DEDDDPRRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPAPPG--------LAAPPACSPVRTR-RRRKLYE
LQAASAPPPPASGHA-------PEPPA-----------------------SPSPRPGSGS
GPEPSDGPIDLSKKPRRQALATP----LTGPTPVLPALADYHECTACRVSFHSLEAYLAH
KKFSCPAAPPPGA-----------------------------------------------
-------------------PEDPAVVCPYCPPNGLVCGDLVEHLRLAHGLLLGKPLAGPG
AEARTPSPAA----------------------------PRDGWPGPA-------------
--GPP-DSPQ-------------------SGPTPAPPTPPSHLDKGVQTP--SKG--TPG
PLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVKL

-----------------------------------------------------MS--RRK
Q-SNPR---QIKRSLGDMEAGEEMQLVGTS-HTEQKATVPE----------APSPPSTDV
SSPPP--PPTPTSPGGPK-EL----EG--QEP-----EPRPTEEEPGSPW--------SG
PDELEPVVQ-DGQRR------------------VRARLSLAMGLSWGPFHGSVQTGASSP
----GQVE-PSPALTLLLVDEACWLRTLPQALTEAEANTEIH--RKDDALWCRVTKPVPA
GGLLSVLLT-AEPRSTPSHPVKK-EPAEPTCPAP---AHDLQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQGAGSPAAAAADEKPKETYPNER

PF00096 // ENSGT00530000063823_1_Domain_1 (420, 443)

V
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
S------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQ--
------------------------------------------------------------
QQHTALHGPLASADLGLAPTP-------SPGLDRKALAEATNGEATAA--PQ------NG
GSSEPPAAPRSIKV----EAVE-EPEAA----------RAPGTGEPGP-QAPSRTPSPRS
P----APARVKAELSSPTPVSSPVPGELS---LAGALFLPQYVFGPDA--------APPA
SEILAKMSELVHSRLQQGAGAGAGG---AQTGLFAGA--PKGATCFECEITFSNVNNYYV
HKRLYCSGRRAPEDASAARRPKAP--PGPARAPPGPP-AEPDAPRSSPGPG------ARE
DGAGGAAT--------------PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYSVHKRYYCAS-RHDPPPRRPAAPPG-TPGPAAPPAPAPVAPLRTR-RRRKLYE
LH-AAGAPPP--------------------PPPGHAPAPESPRPGSG--SGPGTAP-ARS
PGPAADGPIDLSKKPRRPPPGA-----------SAPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPPPGA-----------------------------------------------
-------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG
VEPRTPADRGPSPA-----------PAPAASPQPEPRGPRDGLGPELQEPPPG-------
------------PPQSP---------AAAPEAVPPPPAPPSYSDKGVQTP--SKG--TPA
PLPNGNHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--EDVFPCKDCGIWYRSERNLQAHLMYYCAS----RQSS--GS-PAVDEKPKETYPNE

PF00096 // ENSGT00530000063823_1_Domain_1 (419, 443)

RV
CPFPQCKKSCPSASSLEIHMRS

ENSGT00530000063823_1_Linker_1_3 (443, 449)

HSGERP

PF00096 // ENSGT00530000063823_1_Domain_3 (449, 471)

FVCLICLSAFTTKANCERHLKVHTDTLNGVCH
S------CGFISTTR-ILYSHLVTNHMICQPGSKGEVYSPAPALPNAKPLAPGEYG----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------

------------------------------------------------------------
-------------SLRDMEAREETQAMDIS-PMEEKATSPEAPAIEEP----PSPPREDV
STPTV--PAPPESPEGPE-DMEGQELE--MAPQDEEKEEKEEEAAMASPW--------SG
PEELELALQ-DGQRC------------------VRARLSLTEGLSWGPFHGSIQTRAVSP
----EREE-PGPAVTL-LVDEACWLRMLPQALTEAEANSEIY--RKDDALWCRVTKVVPS
GGLLHVFLV-TEPHSTPRHPVQEP--VEAGGP--APVHTDIQLLPQQAGMASILAT--AV
INKDVFPCKDCGIWYRSERNLQAHLLYYCAS----RQRAGSPA-SVTEEKPKETYPNERV
CPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCH
N------CGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGF---
------------------------------------------------------------
QQHSLMHGALAPADKA---------PTPSSGLDSKALAEVTNGETRVPPQNG--------
GSSESPAAPRTIKV----EAAEEPEATR-----------ASGPGEP-GPQAPSRTPSPHS
P----TPVRVKAELSSPTPGSSPGPGELA---MAGTLFLPQYVFGPEAGT-TTGPAAPQA
SEILAKMSELVHSRLQQGAGSSGAGG--TPAGLFPGT---KGATCFECEITFNNINNFYV
HKRLYCSGRRAPEDTPAVRRPKTAP--GPARATPGTA-AEADQQRSSPGPG------PRE
EEAGGATT--------------PEAEVAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIR
FSRHETYTVHKRYYCAS-RHDPPPRRPPAPTPAPGP---AAPALTAPPVRTR-RRRKLYE
LP-GAGAPPPAVGPAPVPVVPAPTAELPSSPRPASA--SAGP-------------TPTPS
PGPVPDGPIDLSKRPRRQTPDA---------PAALPALADYHECTACRVSFHSLEAYLAH
KKYSCPAAPLRTA-----------------------------------------------
------------------------ALCPYCPPNGRVRGDLVEHLRLAHGLQVAKPAASPG
AEPRTPAERA----------------------------PRDSPDGRTPRSPS--------
--------------------------------PVPENTPSDPADQGVRTPSKGPPASAPS
SGGGGGHR

PF12874 // ENSGT00530000063823_1_Domain_5 (1389, 1407)

YCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK-