ENSGT00530000063678_0 : Linker Region Query Results

-MEEVPGDA-LCEHFEANIL-----------TQNRRQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRG---PSPSAGLPEEGP----
TAAPRSRSRELEAIPYLEGLTTSLCGSCN--------EDPGPDPTSSPD--SATPDDTSN
SSSVDWDTVERQE-EA-PSWDELTVMIPRRPR-----EGPRADSSQRALSLLTRSPVGG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWARLRGESGL-SLERHRSTLTQASS
MTPHSGPRSTMSQASP---PQRDTAQAAST-----RET------------------PRAS
FPHRITQRDTSRASSTQQETSRA--------------------SSTQEDTPRASS-----
-----------------------------------TQWNTPRASSPSRSTQLDNPRTSST
QQDNPQTSFPTCTPQRGNPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSS
PNRA-TRDNPRTSCAQRDNRRASSPIRATQQDNSRMSCAQRDSPR---------------
---------------ASSPNRA--------------------------------------
--------------------------------------TQ--------------------
----------------------------------RENPR----TSC----------AQQD
NPRASSPNRTTQRDSPRTSCARRDNPRASSPNRTTQQENPRTSC----AQRDNPRASSPS
RTTQQENPRTSCARRDDPRASSPNRTTQEENPRTSCA----RRDNPRASSPNRT------
-----IQRDNPRTSCAQWDNPRASSPNRTIQQENLRTSCTRRDNPRTSSPNRAT-RDNPR
TSCAQRDNLKASSPIRATQQDNPR-TCIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSLSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPLYPTAYGA-------PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESEPPHHEPPYIPPAVCIGHRDAPRASSPP------------HTSDAEHQCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHECPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGPQAQCSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPS-Q
-----GQSQLLRRQSSPAPSRQVTKLPAKQ---AELTRRSQA--EPPHPRS-PEKRPEGD
RQLQGSPLPPRTSARTSERELRTQ----------RPLESGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGRLG----PGGWRGCG--EPS----LGAAKAP---
--------EGAWGGTPREYR-E-----------------SWRQPEAWEEKPT--------
-----H--------ELPRELGKRS-------PLTSTPENWGGPAESSQSWHSGTPTAVGW
GAEGVCPYPRGSERQPELDWRDLLGLLRAPGEGVWAR---------LP--SLDWEGLLEL
L-------------QARLPRKDPAGHRDDPARA---------LGPELGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SLALQSQSRA------------QLPSPACTSTQWPK-
--IKVTRGPATATLAGLEQ-TGPLGSRSTAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHNYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDG----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEASQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-MRQAEEREHTLRCCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MGGWKG-PGQRRGR---------------EGPEE-------------
---------------RRR--AAERGGGGGGGGIP--APL-----SPAR---------EPF
PPS------------------------------------------------CLLLPPPRG
AAMTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLQGHGTLKGSLKAGEQR---VGSEVIGRG-GPRKADGQRQS
LDYVELSPL------TQGSPQRARTPARA------LDRPAKQEELERDLAQRSEERRKWF
EATDGRA------TE-TPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGRGERRGPPGDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGEAPQGAPKSQEDGRVPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQLGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRGFIASQGP-----GSGCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MKEISPWKAEP
SPVSQSPGGGWAKHQVESSYFSPERRK-SD-SSWVSSPSRGS------------------
-----------------------------------RSTLPT-------------------
-HSDLV----------RTGGHLTSSVSSLDSGLHRHRSGDGEGRHGLVRQEYTMLADLPK
PKRISHREAFEQE--RSSSRTRSPGRAEVERIFGYERRKTETLEAFQALEEGLVERLDGK
TPLLAKERRLGRRQSSPTLYRELHPMSA-GKHTSERQSRE-----EKPH-PVSSRRY---
-------------TESDQKSWSK-------------------------------------
------SLGPMGPTKQPERDWRSQAETLR-------------------------------
------------------------------------------------------------
--------SRSPTRQPEGDWRSQAETQGPRSPTGKPERGWKSREETLCPRSQTQRSEDNW
RTQEESLCHMNPVQQLERDWRSQGECLYS-----VSSRHQPETTSKSPVSPSQWKLC-AI
PCNASCWP--------------VPSSWRHTPTSPQ---------CQ--------------
-LLRKPRPLS---ERELVGPFSETEASWPL--------RTLDLEGCPPLVQAGEPQKEDT
RESWYTSSLCSSSR----------------QGSSG------------------------A
HFGMK---------------FKKKKKGKGRKKVSVRLGAEPGWRSGDPW-------LNLP
DPARFGLEWSGTQEFPSPAQPHVTGLAVHCPPPPLF--PPPPPELCHCNL-GCNPRAQPW
EMKQPDLLNFKKGWMSILDELGE-----------------WKKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEYAVQRNYGFQIHTKDSTFTLSAMTSGIRRNWIEALRKNV
RPATAPDVTKLSDCNKENSFRSCVSQKGSLRSEEQ-WPGLGSEVISKG-GNRKADGPRHV
FDYVELSPL------NQGSPQRTRGSLKG-----ISDRATKQEDLERDQALRFEERRKWF
EAPDPGVLQGDSPAGALSWKAC-----EQEPLGPALSEDQRSRLNEEIEKKWLELERLPL
KESKRIPLMTLLNQSKGGHGDT-REALEKE------------------------------
-----------------------------------------------VQSLREQLESWRA
RSESLHDTGKSSGDVPLPQGFISQEACERSLAEMESLHQKVMSELQRHHQWELERLRQEK
-ERLLAEEAA---ATAAAIEALKKVHKEEL-NKEVGRTRHVQLGGSG-----------SE
ALRRQHHRSDVDSLKRELQVLSEQYSQKCLEIGDL-TQKADEREQMLQRCQQEGKELLQQ
NQELQKCLSEEIQRLRTFIASQGT-----GDGALHNNERSSCELEVLLR-----------
------------------------------------------------------------
-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MGGWKG----------------------------LGP
RRGR----E--GLELERRAAE-----R-GGGG--------------GGV-------PALL
GPAREPLP----------------------------------PS-CP----RSPP-RQGV
-AMTPDLLNFKKGWMSILDKPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPALAPDVTKLSDCNKENTLHGYGPQKGSLKAGEQR-ASS--EVSGRS-GPRKADGSRQL
LDYVELSPLTQGS------PQRART-------------PAKQEELERDLAQRSEERRRWF
EATDSRAPE-------TPPGEA-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRSERRAPPSDN----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRA
RGEAPQNVARPQEDSHIPPGYISQETCERSLAEMESSHQQAMEQLRRHHERELQRLQQEK
-ERLLDEERA---ATVSAIKAMEKAHQEEL-NRELSKTRSLQQG--------------PD
GLRKQHQ-SDEEALKRELQVLSEQYSQKCLEIEAL-TQQAEEREDTLQRCQQEGQELLRH
NQELHARLSEEIDRLRSFVASQGT-----SNSCGRSSKRSSCELEVLLRVKESQLQYLKK
EVQCLRDELQTMQKDKRVTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAMAALQEKEA
MSNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLRGCGTQKGSLKPGEQR---TGSEVVGRG-GPRKVDGPRQS
LDYVELSPL------TQSSPQRARTLSRSNPERSTPEHPAKQEELERDLAQRSEERRKWF
EATDSRA------PE-TPSGDG-----PRRGLGAPLTEDQQSRLNEEIEKKWQELEKLPL
RENKRVPLTALLNQSQGDRRGTMGDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNISRPQEDGHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLHQGPDG-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGTL-TQQAEEREHTLRVCQQEGQELLRH
NQELHSHLSEEINRLRSFIASQG-----TGNSCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVMQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

------------------------------------------------------------
---------------------------------------------------PVDCPSADS
SAAQPGGQEIGGGVPYLESLTSPQLRNSSEFSQVSR-ATASISPDRSPG--THCPDDTST
PDTEXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXX-
XXXXXXXX----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------XPSHGNQSSRESRSKSRGERGYFSLEKNKLDSAQVSQ
S-LQSGLRSISRNPEKTT--YHDIPQASSLQQSTQQDTTRASSP----HRSTQRDTTRSS
SPHRSTQRDTTRSSSPHQSTQR------DTTR----------------------------
------------------------------------------------------------
-----------------CSSPHRPQRDTTRSSSPHRSTQRDTTRSSSPHRSHKA------
--------------TRSSSPHRSTQRD-TT------------------------------
--------------------------------------------------RSSSPHRSTQ
RDTTRSSSPHRSM----------------------------------------QRDTTRF
--------------------------SSPHRSTQRDTTRSSSPHGSTQRDTTRSSSPHRS
TQQ------DTTRSSSPHRSTQRDTTRCSSPHRSTQRDTTRSSSPHRSTQRDTAWTSSLH
RSTQQD----------TTRSSSPHRSTQRDTAQTSSPHRSSTQRDNPTVF----------
-----TQRDNTRSSSTQRGN----------------------------------------
--------LQASSPAWSTPKENPRASS---------------------------------
----------S-------------QRDNLRVSSTQRDNPGTSSSAQSIQRDNLASSS---
------------HRDNPRTCS---TQRDNPRVSCPARTTPKDNPRSXXXRTSSPTRLN--
------FPKQ------------------------------PTFPNSRFQLPQWPSGSTTS
LFHRT--TSQASS-------RVTSLDSPNPPSVVCIGHRDAPRASSPPRFSQHDPFSFFP
EPHDDESLSPHHEPPYIPPAVCIGHRDAPRASSPPRHSQHDPFPFLPNTSDTES--QSPQ
HDPPQMPPSVCIGHRDAPRASSPPRQSQQEPSLLYQEPLGASSESLAPSTSSVHDPPHVP
PPVC-------IGHRDAPPFSSPPRQAYNDPSLLNQNPPGA-------------------
----------------------------------SSESLTPSMDSLHN--PLQPTLHVCI
GHRDAPRASSPPRHWDSQGP-----------------LLPGEGRRNMEREEYTVLADLPP
PKRLNQKEAMGKQNGSASDHTRSPGRTEVERIFGYERXXXXXXXXXXXXXXXXXXXXX-X
-----XXXXXXXXXXXXXXXXXVTKKPPQP---SEQARRGRA--EPSHTKS-SERRPEGD
RRSKGGSAPPKNLVKLPEREQSQG------------PENDRLGQRQSVGLR------QSQ
WGPPEP----QVSQRHLERGCGCQPGLFTEG-----WRGTSEAGAT----RALDMYP---
--------DSEWRGPTKEHQSCRRLEAPPERAT-------AGLLG---------G---LS
GTVAGSSPPPVPERPAKVSWGSLGELPHSQSLERVDEIDWGTG-----------------
-----GVSPRRPERPLDMDWRDLGELPHPRPGE----TC-----------GTDWGSLREL
L-------------KPRLPGGSPCLQRDL-------AGEW-----RPGPPSAEEAPEREW
QSTSEPAGLVXXXXXXXXXXX--XXXX---------------------------------
------------------------------------------------------------
----------XXXXXXXXXXXADNIQAKGKAVSPPKGRLVTSWRMPGDQ-------PTLF
NPFLI------------------------------------------------SL-GVLK
-WRRPDLLNFKKGWMSILDEPGEPL-----------PSSPWKKHWFVLTDSSLKYYRDSN
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXLSDSNKENTIHGYSSQKGSLKSEEQR-PAS--DVISRG-TNRKADGQRQS
FDYVELSPLTQGS------PQRRVGSVRG-----SER-GAKQDELERDLAQRSEERRKWF
EATDSRAGE-------LSAGEG-----PRKVLGGPLTEDQQSRLSDEIEKKWLELEKLPL
RENKRVPLTALLMQSKGEQNGPSGDV----------------------------------
----------------------------------------TEALRRGXXXXXXXXXXXXX
XGEGSQDTPKPHDDGHIPRGYISQEACERSLAEMESSHQQVMEELQRHHQRELERLQQEK
-EWLLAEETA---ATASAIEAMKKAFKEEL-NKELGKTRSLQQG--------------PE
SLRKQHQ-SDVDSLKRELQVLSEQYSQKCLEIGDL-TRQAEEREHVLRHCQQEGRGLLRQ
NQELHSRLSEEIGRLRSFIASQAS-----SEGLGHNNERSSCELEMLLRVKENELQYLKK
EVQCLRNELQMIQKDKRFASGKYQDVYVELNHIKSRSEREIEQLKEHLRLAMAALREKES
MRNNLDN

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------FKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDYNKENTPH--STQKGSLKAGEQR---VGSEVIGRG-GPRKADGQRQS
LDYVELAPL------TQGSPQRARTPARA------LDRPAKQEELERDXXXX--------
----------------------------------------------XXXEEWQELEKLPL
REDKRVPLTALLNQSRGERRGPPRDS----------------------------------
----------------------------------------REALEKEVQSLRAQLEAWRL
QGEAPQSAPRPQEDSHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVAALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRGFIASQGT-----SDGCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMLQKE-RFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALREKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHNYGTQKGPLKAGEQR---AGIEVVSRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MEEVAGNA-LCVRFEANML-----------AQNCCQNCFRPEEAHG--TRSEELGSPPS
AEAPYCDLPRCPPAPEDPLSASTSGCQSVGVPGLRPRPKRG---PTPPAGFPEEGP----
AAAPGNRNQELAAVPYLEGLTSSPCGSCD--------EGPDSDPSSSPD--CDTPDDPSN
SSSVDWDTVERQE-ET-PSWDKHTVMIPRRTQ-----EGPRTDGARRAASVLTRSPAGG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DAGNGGQSAGQHWAKLRGESGYFSLERHRAALTQASS
TTPQTGPRSAS--------TQRDTAQAASTQ----RDA------------------PRAS
SPPRTTQRDNARTSSTQRDTPRASSTQRNTSRSSSPSR------GPQRDHPRASSTQRN-
---------------------------------------SLQLSSPPRATQQDNPRTAST
QQDNLQTSIPTCAPQRDNPRTTCAQRDNPRASSPNRATQRNNPISSSP------------
-NK----------ASQQDNPRSSSPNRASQRDNSRTSCAQRNNPRSSSPNK--ASQRDNP
RASSPNRATQRDNS----------------------------------------------
------------------------------------------------------------
--------------------------------------R----TSS----------SQQG
NPGASSPNRVTQQDNSRTSCAQRDNPRSSSPNKASQQG--------------NPRASSPN
RATQRDNSRTSSSQQGNPRASSPNRATQRDNSRTSCA----QQDNPRSSSPNRA------
--SQATHRDNSRTSCAQRNNPRSSSPNRASQQ----------DNPRTSSPNRATQRDNSR
TSCAQRDNPGASSPNRTTQRENPRTSCIQQ-----------------------NTLRASS
TQRDNPRTSST-------------KWDHLRSVCTQRDNPHSASFSRNNPGTSTPQCCTQK
DKPRPSSPHRSAQRNNPRNSSPHRTNKDIPWASFPLRPTQTDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QPSSPTRPAQRDPPQP-SGPTQHNSPSRTASSSHNPGHQSAS
RTSSPLHPATRGA--------LQSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPRAAESDSPHHDPPYMPPAVCIGPRDAPRASSPPRHTQFDPFPFLPDTPDAEN--QSSQ
HEPPQFPPAVCIGHRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSTDSLHEPLHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGAS------------------
-----------------------------------MESLAPSTDSLHGSPVPTP--QVCI
GHRDAPRASSPPRHPPSDLVLLAPSPPPGSSGGSRGSAPPGEPRHNLEREEYTVLADLPP
PRRLAQREPGPQAQCSNGGRTRSPGRAEVERLFGQERRKSEAAGAFQARDEGRSQRPG-Q
-----GQSQL-RRQSSPVPSRQVTKPPAKQ---AELARKSRA--EPIHPRS-PERRPEGD
RRLQGSSPPPRTSARTPERELRTE----------RPPESGRAGPRQPVKG----------
WQSEEELPGSQGPQRHLEMSWSSQEEGLG----PGGWRGSG-------------------
-------------APPREYG-E-----------------SWGQPEAWEEPL---------
----------------------------------EKPENWVGPAEFSKSQKPGTPTAMGW
GAEGACPHLHSPERQPELDWRDLLGLLRAPGEGAWAR---------LP--RLDWEALLEL
L-------------QARLPHKDPAGHGHDPAKA---------SGPEPDALEP------E-
-PYSQPEGLA---EATLVNGH--SPGHWPQSPA------------QPPSPASTSAQWPK-
--TTVTSGPETSNMASLEQ-MGQLGSRSPGGGPSSPELEFQPEEPEES------------
----APSRDQDSLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDAPGEPP----SRPLTTTSTPQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYGTQKGPLKAGEQQ---AGSEVISRG-APRKVDGQRQS
LDYVELSPL------TQGSPQRARTPARA------PDRPAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENRRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLETWRL
RGETPPNTPRSQEDGHVPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TQQAEEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRSFIASQGA-----GSGYGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFASGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDYNKENTLHGYGPQKGSLKVGEQR-AGS--EVGGRS-STRKVDGHRQS
LDYVELSPLTQGG------PQRART-------------PAKQEELERDLAQRSEERRKWF
EATDSRAPE-------T--GEA-----PRRALGAPLTEDQQSRLSEEIEKKWQELXXHLT
RETKRVPLTALLNQSRSERRAAPSDT----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRV
RGEAPQNVPRSQEDSHIPPGYISQEACERGLAEMESSHQQAMEQLQRHHERELQRLQQEK
-EQLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQG--------------PD
GLRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHKLRRCQQEGQELLRH
NQELHAHLSEEIDQLRSFMASKGT-----SDSCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQTMQKDKRFTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAMAALQEKEA
MRNSLAE

MMEKVTDNI-SRKHSEASVF-----------AESHCQNCSEVQEAHYDPGTQQETGTPLG
AEVPYCDLKRGPQHPKDTLCILSPSCELVVATALGHKPESLGV---PVEWPSAESP----
VTQPG-CQEIGSGVPYLESLTCTQLRNSSEASQAGK-VAASTSPDCSPG--SHCPDEIST
PDAVDLDAADWLN--K-PRDSERLIMMFSRHQ-----ERAQADSPRKAPSSISRASASG-
DTPGLRRED---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------SSHGNQSSRESRVKSCGESGYFSLERNKLDSAQTSQ
-SLQSGFRSISRNPGPAKSVYHDTPQTSSS------------------QRSTQRDTTRSS
SPHRSAQRDTTRSSSPHR--------------------------SAQRDTTRSSSPH---
---------------------------------RSSQWDTTRSSSPHRSTQRDTTRSSSP
HRS--------------------AQRDTTRSSSPHQSTQR--------------------
-----------------DAPRSSSPHRSTQRDTTRSSS----------------------
----PHRSAQRDTT----------------------------------------------
----RSSSPHQ----------------------------------------SSQQDATRS
L--------------------------SPHRSALRDTTRSSSPHRS----------TQRD
APRSSSPHRSTQRDAPR----------SSSPHRSTQRDV---------------------
-----------------PRSSSPHRSTQRDVTIASSPHQATQRDTTRASSPHGSSTQRDT
TQCSSTQRDKPRPSSTLRDNPRASSPTQPTPKDNPRASSSQRDNPRASTR----------
------DNPGTFSSARSIQRDNLQ---------------------------------ASS
GQRDNPRTSSTRDNPWSSSPARTISKDNPRASSTQRDNPRSSSIQ--------------R
DNPGSSSPMRSSQRSNPRTSSSHRTNRDIPWASFPLRPIQSDGPRA-----SSPARSKQS
EVPWASFPLRPVQGDSS-RTSSPTRSFQLSSKTSQC-----DTLTRGSSC------QSGP
RSSTPPLSSTRTASQTSSLSRSTSLDSPNPPSIVCIGHRDAPRASSPPRVSQHDPFSFFP
DPPDDESQFPHHEPPYIPPAVCIGHRDAPRASSPPRHSQHDPFPFLPNTSDTAE-SQFPQ
HDPPQMPPPVCIGHRDAPRASSPPRQSQQEPSLLYQDVPGASSESLSPSTGSVHEPPHMP
PPVC-------IGHRDAPPFSSPPRHTQHDPSLLYQDPPGAS------------------
-----------------------------------SESLTPSVDSLHDSLQPTL--HVCI
GHRDAPRASSPPRHWDPPGAARYSSPQPGPSGSK--GAGNGEGRHNLEREEYTVLADLPP
PKRLNQKEAVGKPNGSASNRTRSPGRTEVERIFGYERRKSDALETYQALEAGRSPRGGGR
-----AAGQLQRRQSSPALCREVTKKPPQT-----PEQTRKR--EPPHSKS-PERHPEGD
RRSKAGSAPPKNLVRLPERECRARGQLVHSKSLDIPPENERPGQRQPLGLRHLGKSMEEE
WGPAEEACVPRSPSRHPDRDRARAERGLE----RN-FRGQEGHFCT----RPLDMYP---
--------DSQWRGPTKEILGCWRALAEQVCCRRLERLRQSGQLGDWEELAQPGRAVWDC
NGLGELGPPPVPDRPAKVSWGGLGELPGSRRLERADEIDWAGLADLDLLHRPERPSDVDW
RDLGELPHPRSPERPVGTDWGSLGELLGPRSPDSY------------R--EMDWGGRGEP
MLTEGCWLENGGARPPRVPKEAPEREWQSAPE----------------------------
-----PAGLVIHDRQAEVNGY--SPGERLLSPIPS-----VEENGADSGQPSGSAPWPK-
--SRAESLPRAAEPAALQE-DQDKMANELPPGPR------PSEEPEAESSVLPKPGPPGA
ATGQKTPLETPLETEQETADTANNVQAKGKAVSPSKGRLVTSWRMPGDQ-------PTLF
NPF------------------------------------------------LISL-GVLK
-WRRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDSN
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVFTLSAMTSGIRRNWIEALRKTV
RPANAPDVTKLSDSNKENTIHGYSSHKGSLKSEEQR---PASEVIGRG-PNRKADGQRQA
FDYVELSPL------SLGTPQRRGGSVRG------SDRGAKQDELERDLAQRSEERRKWF
EATESRA------GE-PGAGEG-----PRKVLGGPLTEDQQSRLSDEIEKKWLELEKLPL
RENKRVPLMAL--QSKGEQKGPSGDS----------------------------------
----------------------------------------TEALEKEVQSLRAQLESCRL
RGDSSRDTPKPHEDGHIPRGYISQEACERSLAEMESSHQQVMEELQRHHQRELERLQQEK
-EWLLAEETA---ATASAIEAMKKAFKEEL-NKELGKTRSLQQGPES-------------
-LRKQHQ-SDMDSLKRELQVLSEQYSQKCLEIGDL-TRQAEERERILRHCQQEGKGLLRQ
NQELHSRLSEEIGRLRNFIASQAS-----SDGLGRNNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMIQKDKRFTSGKYQDVYVELNHIKSRSEREIEQLKEHLRLAMAALREKES
MQNNLDN

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAIYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLRGYGTQKGSLKIGEQR---TGSEVIGRG-GPRKVEGPRQS
LDYVELSPL------TPSSPQRVRTLSRST-----PERPTKHEDLERDLAQRSEERRKWF
ESTDSRT------PE-TPSGDG-----PRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGHSERRGSPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQSAPRPQDDSHVPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTQSLQQGPDG-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TQQAEEREHTLRRCQQEGQELLRH
NQELHAHLSEEIDRLRSFIASQG-----TGNSCGRSNARSSCELEVLLRVKENELQYLKK
EVQCLRDELQVMHKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-MEEVPGDA-PCEHFEANML-----------TQNRCQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCQSVADPGLRPEPKRG---PSPSAGLPEEGP----
TAAPRSRSRELEAVPYLEGLTTSLCGSCN--------KNPGSDPTSSPD--SATPDDTSN
SSSVDWDTVERQE-EA-PSWDELAVMILRRPR-----ERPRADSSQRAPSLLTRSPVGG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGWSAGQHWARLRGESK-FSLERHRSTLTQASS
MTPHSGPRSTTFQASP---AQRDTAQAAS-----------------------TRETPRAS
SPHRITQRDTSRASSTQEDTPRASSTQ---------------------------------
-------------------------------------WNTPRASSPSRSTQQDNPRTSST
QQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRPSCAQRDNPRASRTSS
PNRAT-QDSPRTSCAQQDNPRASSPNRTTQQENPRTSCARRDNPRASSPNRTTQ--QDSP
RTSYARRDN----PRASSPN--------------------------RTTQRGSPRTSCAR
WDNPRASSPNRATQQDNPRTSCARRDNPRASS----------------PNRTTQR-----
-------------------------GSPRTSCARWDNPRASSPNRTIQQDNPRTSCARRD
NPRASSPNRTTQRDSPRTSCARRDNPRASSPNRTTQQENPRTSC----ARRDNPKASSPI
RATQQDNPRTSCAQRDNPRASSPIRATQQDNPRA-------RRDNPRASSPNRT------
------TQDSPRTSCARRDNPRASSPNRTTQQENPRTSCARRDNPKASSPIRATQQDNPR
TSCAQRDNPRASSPIRATQQDNPR-TCIQQ-----------------------NIPRSSS
TQQDNPKISCT-------------KRDNLRRTSTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSPHNPGHQSTS
RTSSPVYPAAYGA-------PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRAPERELPQHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ
HEPLHLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHECPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPLLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGPQAQCSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPS-Q
-----GQSQLLRRQSSPAPSRQVTKLPAKQ---AELTRRSQA--EPPHPQS-PEKRPEGD
RRLQGSPPPPRTSARTPERELGTQ----------GPLESGRAGPRQPLGA----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG----PGGWWGCG--EPR----LGAAKAP---
--------EGAWGGTPSEYRESW------------------GQPEAWEEKPT--------
-----HELPRE---------------LGKSSPLTSPPENWGGPAESSQSWHLETPTAVGW
GAEGACPYPHGSERRPELDWRDLLGLLRAPGEGAWAR---------LP--SLDWEGLLEL
L-------------QARLPRKDPAGHRDDSARA---------LGPELGPPGTKDVPEQE-
-SHSQPEGWA---EASPVNGQ--SPALQSQSPV------------QLPSPACTSTQWPK-
--IKVTRGPATATLAGLEQ-MGPLGSRSAAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------LTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDG----------------------------------
----------------------------------------HEALEKE-------------
------------------------------------------------------------
--------TA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-----------------------------------------------------AQEPRNA
AESLYCDLPRGPPTPEDPPGTSAPSLQSVADQGLRPEPERG---PSPSAGLPEGAP----
AAVPRSGSQEPGALPYLEGPTSSPGGSCD---QGPD-----------AD--GSSPDDTSN
SSSVDWDSEERQE--GVPGWARLPVMIPRRLQ-----EAPSTDGARRVAR----APAGG-
DAAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DPCRGSRSAGQRWAKLRGEDGGFSLERHRLASGQAAS
TTPQSGPR----SPTPQA--P-----------SAQRDTAQA--------ASAQRSTPRAT
SPPRITHRDDTPRA----------------------------------------------
------------------------------------------------------------
---------------------SSTQRDTPWATSPSRVTQWDTPRASTTRQSNPQL---SC
SPRDGQREHPSTSAAQQDHPHAAFSTCTSW------------------------------
--------------------------------------------------RDHPRTSCAQ
RDNPRASSPNRAT----------------------------------------QRDNPRT
--------------------------SSPNRATQRDNPRTSSPNRATQQDNSKTSCAQRD
N--------------PRTSCAQRDNPRASSPNRTTQRDDNP---RTSCAQRDNPRASSPN
RTTQRD----------NPRTSSPNRTTQRDNPRTSSPNRTTQQDNPRASC----------
-----AQRNNPRASSPN-------------------------------------------
---------------RMTQRDNPRASC---------------------------------
AQRDGPKASCS-------------RWDNLRTACTQRNKPHTSSLRRDNPGAPAAQSCAPK
DRPGPPSPPRAAPRSNARQSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRAKQS
EVPWASIALRPTQGDRS-HSSSPTRPGR-DPPMSSSGPTQPNLPARLTPSSHGPGQHSAP
RPSPLYPRG---A-------PQMPSEPSQAPCAVCIGHRDAPRASSPPRSLQHDPFPFFP
DPRASESDLPHHEPPYMPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDSET--QSPQ
HDPPQLPPPVCIGYRDAPRASSPPRQAPE-PSLLFQDLPRASTESLVPSTDSLHEPLRLP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------TESLAPSTDSLHGSSLLLP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
PRRLAQREPGPQAQGSNGGRTHSPGRAEVERLFRQERRKSEAPGALQARDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQAAKLPVKQ---ADPAGRSRT--QPSRPRS-PERRPEGD
RRLQGTSPPPRTAARPSEREPRSGGGRASSREP----PAGWQGQGEVPGAQGPHGRLERS
WSTQEEGLGPEA------------------------RQELGGFSPG------ATRAP---
--------EGMWGGSP--------------------------------------GTSWEQ
AEA----WGEPPEKPAQRGWGSLQELSGPGQPGSPPEMPWIGPAGSS----PPVASAPGR
GAEGTCPHPHH----PELDWRDLLGLLRAPGDGAWARLP-----------QLDWEGLLQL
L-------------QARLPHKDP---EGHSGDPAKAPGP------ELDPPGPKDAPEQEP
PG--QPEGWA---EATIVNGH--SPGQQ-----------PQ-SLTQPPGPACTSTQWPK-
--TKVTSGPESSVAADLE-HPGPLGGRSDLDRPSLPAPEFQ---PEE-------PEESEP
SRGR----G--SLTDQEQADSADERPAEGKAGSALKGRLVTTWRMPGDR-------PTLF
NPFL------------------------------------------------LSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRACTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGPATQKGSLKAGEQR-----------G-GPRKADGQRQS
LDYVELSPLTQGS------P--------------------KQEELERDLAQRSEERRKWF
EASDSRAPE-------TATGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLTQ----------DS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNPPRSQEDAPIPPGYISQEACERSLAQMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRCLQQG--------------PD
GLRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSRLSEEIDRLRGFIASQGA-----GGS--GRNERSSCELEVLLRVKEKELQYLKK
EVQCLRDELQTLQQDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALREKEA
ARGSLAE

-MEEVPGDA-PCEHFEANML-----------TQNRHQNCFHPEDAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCRSVVDLGLRPGSRRDPS---PSAGLPEEDP----
TAAPRSGSHDLEAVSYLEGLTTSLCGSCN--------EDPGSDPGSSPD--SATPDDTSN
SSSVDWDTVERQE-EA-PSWDELAVMIPRRPQ-----EGPKADSSQKAPSLLTRSPVGRD
T-AGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWAKLRGESGFFSLERHRSTLTQASS
MTPHSGPRSTTPRASP---AQRDTAQ----------------------AA-STCEPPRAS
SPHR----------ITQRDTSRASFTQRNTPRASSPSRST------QQDNPRTSSNQQNN
----------------------------------------PQYSSPQRATQQDNTRTSST
QQDNPQTSFPTCTPQWDNPTTPCARRDDPRACSPDRTTQRDNPRTSYAQRDNPRASSPVR
ASQ-----------------------------------------------------QDNP
RTSCAQRDDPRAFSPNRATRDN-PRISCAQQD--------------N---P---R---T-
-S--S--P--K--R---T--T---Q--Q---D---N---P----------RTS-------
-------CAQRDNPRAFSQIKATQQDNPRMSRAQRDDPRASSPNRTTQQDNPRTSCAQRD
DPRASSPNRTTQRDNPRTSCAQRDDPRASSPNRTTQRDNPRTSC----------------
------------------------------------------------------------
---------------AQRDDPRASSPNRTTQRDNPRTSCAQRDNPRASSPVRASQQDNPR
TSCAQWDNPRAFSPNRTTQRDNPRTSCAQRDNPRAFSPNRAT-RDNPRTSIQQNIPRSSS
TQQDNPKTSCT-------------KRDNLRPTRTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTHSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRVTSSSPNPGHQSTS
RTSSPVYPAAYGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESESPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDTEHRCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEGPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSLVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSRGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQAQHSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAKQ---AELTWRSQA--EPPHSRS-PEKRPEGD
RQLQGSPPPPRTSARTPERELQTQ----------TPLESGQAGPRQPPGA----------
WQSQEEPPGSQGPHRHLERSWSSQEGG-----------------------LGAAKAL---
--------EGTWGGPPGEYRESWGQ------------------PEAWEEAAT--------
-----HEPPRE---------------LGKRSPLTSPPENWGGPTESSQSRRPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWA---------RLP--RLDWEGLLEL
L-------------QARLPCKDPAGHRDDLA---------RASGPEVGPPGTKDVPKQE-
-SHSQPEGWA---EATPVNGHS--PAPRPQSPA------------QPPSPACTSTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGSRSTAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSLGV--L
RWRRPDLLNFKKGWMSILDEPGEP----PSPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENALHNYGTQKGPLKAGEQR---AGVEVVSRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTLART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPSSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQETAEILGALPVCAGTQVMSKMRRHLSRRRHWLGHEK
EGWLVSVVEA---FSAETFRGLGKKKKKKKKKKKKKKNKKAWQGQDNLCSP---------
LLLLWGR-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MEQVAGNV-PCEHFQISAL-----------AQRLCQNCFHPAEAHG--AGPQERGSPPS
AETLYCDLPRRLPAPEDQLSALTSDCQSVVGLRSGP--QRGL-----LSGLP--------
--EARSRSLELEAVPYLDGLTSSPSGSCD--------EVPNSGTSSSPD--GYTPDDTSS
WSSVDWDTVERQEEALSADPDQLTAMIPRRPQ-----EGPRADSARRAPSLLTKPPVGG-
DAAGQRKEDT--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------SSGQQHWAKLRGGSGFL-LKRLRSAPAQASS
TAPQSGPQSATSQASF---PHRSAQRDAVQ------------------AVYTQRDNSRSS
SPRRNPGQNNSRTSAIQQQTT-------------------------RWDKPRTSSTQQ--
---------------------------------------TSSVFSPSRTIQIENPRTSST
EQDNPRTS-PTRSPQRDNPRTSCAQQDNFRAASPNRTTQQENSRTSCAQRDSSRT---SS
PNRTTQQDTPRTFCVPWDNLRATSPSRTTQRENSKISCAQRDNPRTSSPNQTV-------
-----------------------QWDNPRTSCAQRDIPRTSS--SGRLTQRDNPRTSCVQ
RDNPRTSSPNQTTQRDNPRTSCAQQDNPRASSPPD----DRDNPRASSPNRTTQRDNPRA
S----------------------------------------SPNRT----------TQRD
NPRASSPNRTTQQDNSRTSCAQQDNPRASSPNRTTQRDNPRASSPNRTTQRDNPRTSSPN
RTTQQDNSRISCAQRDKPRASSPNRTTQWDNPRASSPNRTTQQDNPRTSSPNRA------
-----TQWDNSRTSCAQRDKPRASSPNRTTQWDNPRA----------SSPNRTT------
----QRDSPKTSSPNQAIQRDNPRTSCTQQ-----------------------NTLRTTF
TQRGNRKTSCT-------------QQDNLRTPSSQRGRKQSSSSKWENPGISSSRCCTPQ
DNPRPSSPHRCTPRSNPRNASPHRTNKDIPWASFPLRPTQSGGPRT-----SSPSRSKQN
EVPWAFIALRPIQGDRS-QTSSPTRPAQHDPLQS-SGPTSHSSPSQATSFSHNPGHQNAY
RTSSPLYPLSHGAS---------QTDPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPRGSESDSVHHDPPYIPPAVCIGYRDAPRASSPPRHAQFDPFPFLPDTSDTDAESQSPQ
HDPPQLPPLVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSTDSLHESPHIP
TPVC-------IGHRDAPYFTSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGVPMLPP--QVCI
GHRDAPRASSPPRHPPSDLALLALSPPPGSSGESRGSVPPGETRHNLEREEYTMLADLPP
PRRLVHREPGPQVQGSNGGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGQSKRPS-Q
-----EQSHLLRRQSSPALSREVTKPSLKQ---TEPARRSRA--ETPHTRS-PERRPDGK
QRLQGSSQHPRTSARTSERDWRTD----------RPQESGQAGLRQPLEG----------
WLSEEGPPGSQGSHKHLERAKSSQEEAPG----PRGWPGLG--ESS----QAASGAP---
--------DGMRRGPLRESEESWGQ-----------------QSEAWEEEPPEVR-----
----------------PEGLGQRSS------LASPPEGTRASPTE-SQFGQPETSGPSSQ
GPEGAGAHPCGLNGRPQRDWRDLVSLFQVPGEAVWAH---------LP--RLAWEGVLEL
L-------------QAQLPCRDPAGHWGVPAKS---------SGTELGPSGTKGALEPE-
-RHSQPEAWA---KATVVSGH--SPKQWPQKPA------------QMPSPACTTTQWPK-
--TKVTSGSESLTMADLEE-PGCLGS--PTEGPSSPEQEFQREEPEES------------
----EASRGQDSLNDRKQTDSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPL------SLTITFSSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXLSDYNKENALHGYSTQKGSLRAGEPR---VGLEVISRG-SSRKAEGQRQS
PDYVELSPV------TQSTLQRARPLARP------PDRPAKQDELERDLAQRSEERRKWF
EATDSRA------VE-TPSGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLHRSRSERRGPSSDS----------------------------------
----------------------------------------HEALEKEVQCLRAQLEAWRL
RGEAPQDAPRSQEDNHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-----NKTRSLQQGPDG-------------
-LRKQHX-XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX--XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALREKEA
TRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------C
QAGA----Q--ELELAHCPAD-----L-GG-D--------------SSH-------PGLH
APVAGLSA----------------------------------QQ----------------
-----------LPAPRSSHLSSQ-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPALAPDVTKLSDCNKENTLHGYGPQKGSLKAGEQR-ASS--EVSGRS-GPRKADGSRQL
LDYVELSPLTQGS------PQRART-------------PAKQEELERDLAQRSEERRRWF
EATDSRAPE-------TPPGEA-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRSERRAPPSDN----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRA
RGEAPQNMARPQEDSHIPPGYISQETCERSLAEMESSHQQAMEQLRRHHERELQRLQQEK
-ERLLDEERA---ATVSAIKAMEKAHQEEL-NRELSKTRSLQQG--------------PD
GLRKQHQ-SDEEALKRELQVLSEQYSQKCLEIEAL-TQQAEEREDTLQRCQQEGQELLRH
NQELHARLSEEIDRLRSFVASQGT-----SNSCGRSSKRSSCELEVLLRVKESQLQYLKK
EVQCLRDELQTMQKDKRVTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAMAALQEKEA
MSNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------QEYTVLADLPK
PKRLGRGDAA--E--RCGS------RVEVERIFGCERRKSETLEAFQALEEGRVERLDGK
TPLPPSKGRLGRRQSSPSLPREGQRL------SWHPEQRSRDPKELRRS-PSPARLPERT
GTPLRPVC----PSSRAERDWRK---PRDSSSPTRQLERGSSSPRS----------PSPN
FRSEQRAGRAASPPQRSEKDWRSQTERG----RAACWPSTGGREEMGEPRGA--------
---SA--RQGL------------------R-----------ETARMWLAEP---------
--AGK-TAASPPREGHGR--RVERPRLRPTSPTRPLEQDWKGRGDGQQALKPEKDSKHDW
KAPELTQDSNNPEKPLESDWGRCAERRRP---------P--GT-----------------
----GVLP--------------PAPRWEGTPLLLA---------LA--------------
--------------------FSPRSPSWVEAPSQHKAPREASTKPPMPVRDATRP-RGT-
--AGVTPQPCAHSP----------------DGKTE-------------------------
--------------------------------------ARSHWPDPL---------AELP
---SFPYLLLAAGPFASSLSLRR-LLFSSVSPPGLRLPHRWPVPCCQPCY-GKNTARVAA
ELRLPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAIFTLSAMTSGIRRNWIEALRKNV
RPVSAPDVTKLSDCNKENALRNCVPARGSLRAEEQQQQRPGSEGSTKS-SPWKADGQRHA
FDYVELSPLQQDP-PSQGSPPRTRGSLRG-----SERAPKHHEDLERDLALRSEERRRWF
ESPDSGVPTADGLGGDSSRKAG-----EPDLPPSPLSEEQRARLNEEIEKKWLELERLPL
KDSRRVPLTALLNQGKGNQGGDLNEALRKEVRA---------------------------
----------------------------------------------SVPSERCRLESCRA
KNE----ATKPQGDSHVPRGYISQEACERSLAEMESSHQQVMEELQRHHQRELERLRQEK
-ERLLAAEPDPPLSLPAAIEALKKAHREEM-NKELGRTRSFQQCGSS-----------SD
ALQKQHH-ICLSRGRAHICLY----YAKLLRFSCMTRSSQEEREQTLQRCQQEGKQLLRK
NQELQTRLSDEIGKLRSFISSRCS-----GDRS-QNNERSSCELEVR-------------
------------------------------------------------------------
-------

-MEEVPGDA-PCEHFEANMP-----------TQNRRQNCFHPEEAHG--ARYQKLRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCRSVVDPGLQPGSRRG---PSPSAGLPEEGP----
TAAPRSGSHDLEAVPYPEGLTISLRGSCN--------EDPGSDPGSSAD--SATPDDTSN
SSSVDWDTVERQE-EA-PNWDKLAVMIPRRPQ-----EGPKADSSQKAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DMGGGSRSAGQHWAKLRGESGFFSLERHRSTLTQAAS
MTPHSGPRSTTPRASP---AQKDTAQAAST-----RET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASFTQRNTPRASSPSR------STQQDNPRTSSNQQNN
PQYPSPQRATQ----------------------------------------QDNPRTSST
QQDNPQTSFPTCTPQWDNPRTPCARRGDPRAFSPDRTTQRDNPRTSCAQRDN--------
-------------------PRASSPDRTTQRDNPRTSCAQRDNPRAFS---PNRATRDNP
RTS----CAQRDNPRASSPNRT--------------------------------------
------------------------------------------------------------
-------------------------------T-QRDNPR----TSC----------AQRD
NPRASSPDRTTQRDNPRTSCAQRDNPRASSPDRTTKRQ---PQN----ILRPNILASSPN
RTTQRDNPRTSCAQRDNPRASSPDRTTQRDNPRTSCA----QRDNPRASSPDRA------
------TRDNPRISCVQRDNPRTSSPNRTTQ------------------------RDNPR
TSCAQRDNPRASSPNRASQQDNPR-TSIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRDNLRPTRTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRVTSSSPNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESELPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDAEHRCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEGPQIP
IPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSLVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSRGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQVQHSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAKQ---AELIWRSQA--EPPHSRS-PEKRPEGD
RRLQGSPPPPRTSARTPERELQTQ----------RPLESGQAGPRQPLGA----------
WQSQEEPPGSKGPHRHLERSWSSQEGGLG-----------------------AAKAL---
--------EGAWGGPPGEYR-E-----------------SWGQPEAWEEAAT--------
-----H--------EPPRELGKRS-------PLTSPPENWGGPTESSQSRRPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWAR---------LP--RLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPAPWPQSLA------------QPPSPACTSTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGSRSTAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GSLL
ASCWPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHNYGTQKGPLKAGEQR---AGVEVVSRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCRRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------LGGWKGPGP------------
----------------------------------------------------------RR
RGGGPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDNVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENTLHSFGPQKGSPKVGEQR---AASEVIGRG-SPRRVDGPRQS
LDYVELSPL------TQASPQRARTPART------PDRPTKQEELERDLAQRSEERRKWF
EATDSGG------PE-TPTGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RESKRVPLTALLNQSHSERHTPSRDN----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQSAPRPQEDGRTPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLEEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSERYSQKCLEIGAL-TRQAEEREHTLQRCQQEGQELLRH
NQELHTRLSEEIDRLRSFIASQGS-----GNSCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVLQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
TRNSLAE

-MEEVAGNA-PCEHFEANVL-----------AQSCCQNCFRPEEAHR--PRHQEPRSPPS
AGVPYCDLPRRPPASEDPPRSSTSGCQFVVRPGLAPGPERG-----RSAGSSAEVP----
TAAPGSRSQEPETVAYLEGLASSLGGSFD--------EGLDSGTSSSPD--CGTPDDTSD
SSSVDWDTVERQE-EA-PSGDELTVMIPRKPQ-----EGPRADSARRAPSLLTRPPVGG-
DTAGRRKEDCLALSGPGERVRGKKLPWVCIRGAAGE------KKKPGLGVLTQPG---GS
GSGGERHLSQHPSCAQRARQSSELAAGCTVGLSPSVTLISQRSSSQAPGSLESI-SGRDG
GSSQNPSA---ASRTGKGKLLVAA------SRPTSPSPRSHGLLS---------------
-ELLS-TNLCRD----------------------RP-PPPPPGP-----SSCPSSSA---
--ASHPVT---ESGGVQCQI---------PKLRLRQAFKPRPIRAVGSALIICPREQGKV
-------ERETPSLTLNQPLLSLDTCSGSQSAGQHWAKLRGESGYF-LERHRSALTQASC
ATPQGGPRSATPQASS---FHRSA------Q----RDVAQ--------TAYTQFNTARAS
SPTQIAPRDNLRTLSTQQDIPRTSFTQHNTPRASSPSR------IAQRDNPRTSSVQRNN
----------------------------------------PQVSSSTRATGQDNSRTSSI
QQDNPQTSFPTCTPQRDNPRGS----------TPNRTTQRDN------------------
-----------------------------------------------------------P
RGSA--------------------------------------------------------
------------------------------------------------------------
----------------------------PNRTTQRDNPRGSSPNRT----------TQRD
NPRGSSPNRTTQRDNLRSSCGQRDNPRVPSPNRTTQRDNLRASC----------------
------------------------------------------------------------
---------------PQQDNPRGSSPNRTTQRDNLRASCPQQDNPRGSSPNRTTQRDNPR
SSCAQWDNPRVPSPNRTSQRDNPRASCIQQ-----------------------NTPRTSS
TQRDNPKTSCT-------------QWNNPRTSYTQRDNPQSS-AQRDNPGTSSPRCCTQR
DNPGPSSPHRSTPRNNPRNSSPHRTNKDIPWASFPLRPTQSEGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRPPQTSSPTRLTQRNPPLSSSGSTQHNSLSRAASSSHNPGLHSAS
RTSSPLYPATRGE-------PQTSSEPSQPPCSVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHASESEPPHHNPPYIPPAVCIGHRDAPRASSPPRYLQHDPFPFLPDTSDAET--QSPQ
HDPPQFPPPVCIGYRDAPRASSPPRQP-PEPSLLFQDLPRASTESLAPSTDSLHEPPHMP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPMLPP--QVCI
GHRDAPRASSPPRHPPSDLGLLAPSPPPGSSGGSRSSAAPGETRHNLEREEYTVLANLPP
PRRLAQREPGPQ--GSNGGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQARP-P
-----SQG--PGTSCSPPPHPQVTKPLAKQ---AEAARRSQA--EPPHHRS-PKRRPEGD
RRLQGSSLPPRTSARTPERERRTE----------RPLESGRVGPRQPLGG----------
WQSQEGAPGTQGPRGHLERGYSSRQEDPS----------LG--KPS----WGVARAP---
--------EGTSRGPIRESEESWGQLGGPT--------GHRGQAEAWEEPPS--------
-----DGLRESPDRPAQ--------------PKSPPENSRVGPAEFLKSQRPETPTARSW
EAEGTCPHLHSPERRPELDWRDLMGLLGAPREGAWACTEESTLTSHLP--RLDWEGLLEL
L-------------QAQLPRRDPSGHWGTPAPA---------SGPEVGSPGTIGAPEFE-
R-QGQPTSWE---ESTPVNGQ--SPGQWPQSSA------------QPPSPACTSTQWPK-
--TKVTSGPETSAMAGLEE-MGQLGGRSPAEDPSLPEWEFQSEEPEES------------
----EPSKGQDSLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEERKLTPLPLLTAASPSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYSTQKGSLKAGEQR---GGSEVIGRG-SLRKADGQRQS
LDYVELSPL------TQGSPQRARTPART------LDRPAKQEELERDLAQRSEERRKWF
EATDSRP------PE-TAGGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENRRVPLTALLNQGRGERRGPPGDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGEVPQGAPRSQEDSHIPPGYISQEACERSLAAMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVAALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRGFIASQGT-----GDGCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMLQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKES
LRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MGGWKG----------------------------LGP
RRGR----E--GLELRRRAG--------------------------GCS---------T-
--------------------------------------------------------LRFP
-AQVPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTPHGFGPQTGSLKAGEQR-AGS--EVSGRG-GPRKTDGPRQA
LDYVELSPLTQGG------PQRART-------------AAKQEELERDLAQRSEERRKWF
EATDSRAPE-------TPSGEA-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRSERRAPPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRV
RGEAPQSTPRPREDSHVPPGYISQEACERGLAEMESSHQQAMEQLQRHHERELQRLQQEK
-EQLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQG--------------PD
GLRRQHQ-SDVEALKRELQVLSEQYSQKCLEIGTL-TRQAEEREHKLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFVASKGT-----SNSCGRGGERSSCELEVLLRVKENELQYLKK
EVQCLRDELQTMQKDKRFTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAMAALQEKEA
MRNSLAE

----------MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQ--ACSQEPHSPSS
AEAPYCDLPRCPPALQDPLRTTTCVGQSVNSLGLGLGQEPQR-VWSPTTALPAEGP----
AAASK--NQDSEGIPYLEGLACSSCTDDNK--DEDEDEDPNSNTSSSQD--SNTPHDTSN
SSSVDWDTAERPG-VV-PNRNRLTDMIPRRPQ-----EGLRADSAQKA----IRSPARG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------NSGSGGQNAGQHWAKLRSESGYFSLERQRSGQTQASS
GTPPSGPRSTT-QASS---AQRDVFQAAPAQ-----------------------EAPQTS
SLPRNTQRDTQRGT----------PRTSSPSKASQRDT------SRVMSTQRKN------
------------------------------------------------------------
------------------------------------------------------------
-------------------TPLSSPLRATP--------------E---------------
------------------------------------------------------------
-----------------TLKTSAPEDGTH-------------------------------
-------------------------------VTPSPCAQDSSLNRTSQRDSSRTPCVQRD
NPRASSPNRTTQRDNPRTPCAQRDNPR---------------------------------
---------T--------------------------------------------------
-------------PCAQRNN--------------PRTPCAQRDNPRASSPNRTAQRDNPR
TPCVQRDNPRT--------------SCTSQ-----------------------NTPRTPS
TQADKTTASCS-------------KWEHLRSACTQRDNP--RTF---------SQGCTQK
DNPGPPSPRRATQGSNSRNPSPHRTNKDIPWASFPLRPTQSDSPRT-----SSPSRTKQN
QVPWASISLRPTQGDKP-QTSAPTRLAHNDPPQQYSPSL----ATSSSSSSHNPGHSSAS
RTSSPLHAAPRGA-------PQTSLESSQSPCTVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEPS-FFQDLPRASTESLVPSTDSMHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSIDSLHGCPLLPP--QVCI
GHRDAPRASSPPRHPPSDIGLLAPSPPPGSS-GSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPS-Q
-----GQSQL-RRQSSPAPSRQVTKPSAKQ---AEPTRQSRT--GPPHPKS-PDKRPEGD
RQLQRTSPPARTPARPPERKAQIE----------RHLESGHTGPRQSLGG----------
WQSQERLSGPQNPNRHPEKSWGSQEEGPS----LGGWPELE--GPS----------L---
--------EGIWRGPPQEHRERW------------------GHSEAWDEPPS--------
-----NGIQGA----PPRGQGRLQELSRPHQPTPSSENSWVGPAECLCALQPEASTAVGW
RAEGTSPHKRSAERPPDLDWRDLLGLLRAPEDGAWTR---------LP--RLDWEGLLEL
L-------------QARLPQKDPARHWHDPAKA---------SGPELGSSGTEDTLKTE-
-PQTQPEGQA---KATLANGH--RPDQQSESPA------------QLPSPACTSTQWPT-
--TKVTSGPETSPLAALEQ-IDHLESHSP------RDLEFQPEEPEAS------------
----EPSRGEDSRADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDQ-------PALF
NPY------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILAEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYGTQKSSLKIGEQR---TGSEVIGRG-GPRKADGPRPS
LDYVELSPL------TPSSPQRMRTLSRST-----PERPTKQEDLERDLAQRSEERRKWF
ESTDGRT------PE-TPSGDG-----SRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQAHNERRGPTSDSHEALEKESSRGPTSD-------------------
---------------------------------------SHEALEKEVQSLRAQLEAWRL
RGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPES-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVMQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-MEEVPGRV-PCEHFEANML-----------TQNHCQNCFRPEEAHR--ARCQELRSPSG
AEVPYCDLPRCPPVPEDPLSSSTSGCQPVVDLGLRPGPKRA---PSPSAGLPEEGP----
TATPRSRSQELEAVPYLEGLTSSLRGSGN--------EDPSSDPSSSPD--SATPDDTSN
SSFVDWDTAERQE-EA-LSWNELKVMIPRQSQ-----EGPRAYSSQRAPSLLTRSPMRG-
DAAGQKKEGESFCQVGSHASGYVMVW----------------------------------
-----------------------------G-----SPDS---------------------
-------------------HLR---------------------D----------------
-KER--------------------------------------------------------
--------------------------------------------------------WNMR
-------AVWTPPLTLSLSLLPPDTGGGGRSAGQHWAKLRGESRYFSLEQHRSPLTQASS
MTPHSGPRSATPQASP---GQRDIAQAASTQ----RDT------------------ARAS
SPHQITQRDAPGPSSTQQDTSKASSTQRKTPRASAPSR------STQQDNPRTSTNQQNN
PQLSS----------------------------------------PLRATQKDNPKTSFT
QQDNPQTSSPACTPQRENPRTPCAQRDNPRPSSPNRATQRENRRMTCAQWDNPRDSS---
PNRATQQDNLRTPCAERDNPRASSPNRATQQDNLR-------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------TPC----------AQRD
NLRASSPNRTTQRDNPRTPCAHRDNPRASSPI----------------------------
----RDNPRTPCAQQDNPRASCP-------------------------------------
------IRDNPRTPCAQRDNLRASSPNRTAQRDNPRTPYN-------PRTPCAQ-WDNPR
TPCAQQDNPSASSPIRATQRDNPR-TSIQQ-----------------------NTPRSSS
TQQDNPKTSST-------------KWDKLRPTCTQRDHTHSLSFQRDNPGTSS-QYCTQK
ENLRPSSPHRFTQRNTPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSSGPTQYNLPSRATSSSHNPGHQSTF
RTSLPLYPATCGA-------PLTSSEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPSVPESESPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDMSDAEHQCQSPQ
HEPLQLPQPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSSDSLHGFPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGPQARSSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQTQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKPPAKQ---AELAQRSRA--EPPHPRS-PEKRPEGD
RRFQGSLPPPRTSARTPERELRTQ----------RPLESGRVDPRQPLGA----------
WQSQEEPPGSQGPHRHLERNWSGQEGGLG----LGGWRGCG--EPS----LGAARAS---
--------EGTWGGPPREYR-E-----------------SWGQPETWEEKPT--------
-----H--------EAPRELGKRS-------SPMSAPENWGGPAETSQSWQPGTPTAVGW
GAEGACPYPHGPERQLELDWRDLLGLLRAPGDGAWAR---------LP--RLDWEGLLEL
L-------------QARLPHKDPAGHRGDPARA---------SGPELGSLGTKDAPEQD-
SHS-QPEGQA---EATPVNGY--SAAPRPQSPA------------QPPSPACTSTQWPK-
--TKVTRGPATTTLTGLEQ-TGPLGSRSPAESPSLPELQFQTEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKPGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDDPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPARA------PDRLAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTENQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPQSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDSHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TQQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKEA
MRNSLAE

-MEEVPGDA-PCEHFEANML-----------TQNRRQNCFHPEEAHR--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCRSVVDPGLWPGSRRG---PSPSAGLPEEGP----
TAAPRSGSHDLEAVPYLEGLTTSLRGSCN--------EDPGSDPGSGAD--SATPDDTSN
SSSVDWDTVERQE-EA-PNWDKLAVMIPRRPQ-----EGPKADSSQKAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGSRSAGQHWAKLRGESGFFSLERYRSTLTQAAS
MTPHSGPRSTTPRASP---AQKDTAQAAST-----RET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASLTQRNTPRASSPSR------STQQDNPKTSSNQQNN
PQYPSPQRATQQDNPRTSSTQQDNXXXXXXXXXSSNQQNNPQYPSPQRATQQDNPRTSST
QQDNLQTSFPTCTPQWDNPRTPCARRGDPRASSPNRATQRDNPRTSC-------------
--------------------------------------AQRDNPRASS---PNRATRDNP
RTS----CAQRDNPRASSPDRT--------------------------------------
------------------------------------------------------------
-------------------------------T-QRDNPR----TSC----------AQRD
NPRASSPDRTTQRDNPRTSCAQRD------------------------------------
------------------------------------------------------------
-------------------NPRASSPNRTTQ------------------------RDNPR
TSCAQRDNPRASSPNRASQQDNPR-TSIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRANLRPTRTQRDRTRSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRVTSSSPNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESELPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDAEHRCQSPQ
HEPLQLPTPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEGPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSLVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSRGSRGSVPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQVQHSSGGRTRSPGRTEVERLFGQERRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAKQ---AELIWRSQA--EPPHSRS-PEKRPEGD
RRLQGSPPPPRTSARTPERELQSQ----------RPLESGQAGPRQPLGA----------
WQSQEEPPGSKGPHRHLERSWSSQEGGLG-----------------------AAKAL---
--------EGAWGGPPGEYR-E-----------------SWGQPEAWEEAAT--------
-----D--------EPPRELGKRS-------PLTSPPENWGGPTESSQSRRPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWAR---------LP--RLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QAEGWA---EATPVNGH--SPAPWPQSLA------------QPPSPACTSTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGSRSTAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHNYGTQKGPLKAGEQR---AGVEVVSRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCRRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MGGWKG-P---GQRRGREGP------------E--------------
---------------------ERRRAAERGG-----GGGVAAPRSPARE-------PL-A
PRC------------------------------------------------LLLP-PPRG
AAMTPDLLNFKKGWMSILDEPGEPP----SPSLTSTSASQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPASAPDVTKLSDCNKENTLHSYGTQKGPLKAGEQR---ACSEIIGRG-GPRKADGQRQS
LDYVELSPL------TQGSPQRARTPARA------PDRPAKQEELERDLAQRSEERRKWF
EATDSRA------SE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPSSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRSLEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHVRLSEEIDRLRSFIASQ-------GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQTMQKDKRFASGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

--------W-SCEQGEGVTLLPTQGTAWATAAVPVAGLQGPQGDSHQ--ACSQEPHSPSS
AEPPYCDLPCCPLAPEDPLGTTTCAGHSVEGLG--LRQGPQR-GWSPTAALPAEGP----
ATAPRNRYQDPEVVPYLEEP--------------------NSDTSSSQD--SNTPHDTSN
SSSV--DTVERPG-VV-PNGDRLNVMILRRPQ-----EGLRADSAQRI----TRSPARG-
DPEGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DSGSGGQSAGQHWAKLRAESGYFSLERHRSGKTQASS
GTPPSGPRTTN-QASS---AQRGVFQNASAQ-----------------------ETSQAS
SIPPNAQRDTPRTL----------ATQRSGPRMSSPSR------VSQRDTPRTMSTQRSS
------------------------------------------------------------
------------------------------------------------------------
-------------------TPLSSPLRATP--------------D---------------
------------------------------------------------------------
-----------------SLKTCTPQNSPH-------------------------------
-------------------------------VVSSPCVQASSLNRTTQRDNPRTPCAQRD
NPRSSSPSRTTQRDNPRTPC--RDNPRSSSPSRTTQRDNPRIPC----AQRDNPRSSSPS
RTTQRDNPRT--------------------------------------------------
-------------PCAQKDNPRSSSPSRTTQRDNPRTPCAQKDNPRSSSPSRTTQRDNPR
TPCAQKDNPRSSSP--------------IQ-----------------------NTPRTPS
TQGNKTSASCS-------------RWEHLRSACTQRDNPGPPPF---------SQGCTQK
DNPGLSSPRHATQGSSSRNPSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRTKQN
QVPWASISLRPTQGDRT-QTSAPTKLAHHDPPQHSLPSL----A----SSSHNPGHPSAS
RTSSPLHPAPRGV-------PQTPSEPSQPSCAVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDAEN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEP--FFQDLPRASTESLVPSTDSLHEPPHIP
PPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSIDSLRGSPLLLP--QVCI
GHRDAPRASSPPRHPPSDLGLLAPSPPPGSS-GSRGSAPPGETRHNLEREEYTMLADLPP
PRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDKGRSQRPS-Q
-----GQSQL-RRQSSPVPSRQVTKPSTKQ---VEPAR---T--EAPHPKS-PEKRPEGD
RWLQRSSAPARTSARPPERKAQTE----------IHLESGCTGLRQPLGG----------
WQSQEELSGPQSTNRHTEKSWDSQEEGPG----LGGWPELG--SSS----------L---
--------EGIWRGPPQEHRERW------------------GQSETWKQLSS--------
-----NGLQGR----PPTGQGSLQELSRPHQPTTPRDSSWAGPTECLCTLHPEATAGMGW
RAEGASPHQDSLEKPPDLDWRDLLGLLRASEDGAWAR---------LP--RLDWEGLLEL
L-------------QARLPQRHPAGHLRDPARA---------SGPELGSSGTDDTLKTE-
-TQTQTEGWA---KATQANGH--SPGQQSESPA------------QVPSSACTSTQWPT-
--TKVTSGPATL--SALEQ-TDHLGSHSP------PDQAFQPEEPEGS------------
----EPSRGEDSLADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PALF
NPY------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGCGTQKGSLKIGEQR---TGSEVIGRG-GPRRVDGSRQS
LDYVELSPL------TPSSPQRVRTLTRST-----SERPPKQEDLERDLAQRSEERRKWF
ESTDSRN------PE-TPSGDG-----PRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNHGRSERRGPPNDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRLQENSHIPPGYISQEACERSLAEMESSHRHVMDQLQQHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-NRELSKTRSLQQGPDG-------------
-LQKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TQQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVMHKDKRFT-GKYQDAYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

---------------------------------------------------SQEPQSPLS
AEVPYCDLPHRSPASEDLLGASTSGCQSAVGLGLGPGPERRRA--RGPAGLPTEGP----
TAAPRSGSREAEAVPYLEGPASHLCHGFD--------RGPDSRTGSGPD--RDAPDGTSD
VSSVDWDTVERWE-AV-PSWDKLTVMIPRKPQ-----EGPRADSSRRAPSVLNWSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGSGSRSAGQHWAKLRGESRYFSVERHQPALNPAAS
GTPQSGPRSATSQASS---LHPS-------------------------------------
SPARTTQRDNPRTSSTQQDVPRTSSTQRNTPRASSPSR------TTQRDNLRTSSTQLNN
----------------------------------------PQVSSPTKATQEDNSRTSST
QQDNPQTSFPTTSSSS--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------PNRSTQQESSRTSCAQRD
NPRASSPNRPTQWESSRTPCAQRDNPRASSPNRSTQWESSRTPC----AQRDNPRASSPN
RPT---------------------------------------------------------
------QWESSRTPCAQRDNPRASFPNRSTQRESSRTSCAQRDNPRASSPNRPTQRESSR
TPS--------------TQRDNPRTSCIQQ-----------------------NSLRTSS
TQRANPKTSCT-------------QWDNLRTSFIQRDNPRSFSFWQGNPGSSSPQCCTQQ
DNPGPSSPRRSTQQNNPRNSSPHRTNKDIPWASFPLRPTPSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QASSPARPAQRDPLQSSSGPTQHSSSSRATSSSHGPGHHSAP
RTSTLLHPATHGA-------PQTSSEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHASESESPHYDSPNIPPAVCIGHRDAPWASSPPRHTQFDPFPFLPDTSDAEI--QSPQ
HAPPQFPPPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPTD-SL-HPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSL-FQDPPGTS------------------
-----------------------------------MESLAPS-DSLRGSPVLPP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRSSMPPGETRHNLEREEYTMLADLPP
PRRLAQRDPGP--QCSSGGRTRSPGRAEVERLFGQERRKSEAPGAFQARQEGRSQRPG-Q
-----GQSQLLRRQSSPALSREVTKPLVKQ---AEPAQRSRA--EPPRPRS-PERRPEGD
RRLQGSSPPPRTSARTPERQQRTE----------RPPESGRVGQRQPLVG----------
WRSQEELPGSRGPHRQLERGWSSQEEDLG----LGGWQGLG--EPS----WGAARAP---
--------EGTHRGPPRESEESW------------------GQLEAWEEPPD--------
-------------RPAQRGWGSLQELSSPHQPGSPPENSRAGPAEFSKSWKPEMPIARDG
GVEGTCPHLHGPEWRPELDWRNLVGLLGAPREEAWARMEEPMLTSRLP--RLDWEGLLEL
L-------------QAQLPRKDPAGHWGGLATA---------LGSEVGFPGTEGVLERE-
Q-HGQPEGWA---EATLVNGH--SPGQWPQSSA------------QPPSPACISTQWPK-
--SKVISGPEALAMAGLEE-TGQLGSRSPAEGPSSTQWEFQPEEPEES------------
----EPSRGQDSLTDEKQTDSADKRPAEGKPGSLLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENTLHGHGTQKGSLKAGEPR---VGSEVISRGGGLRKADGQRPS
LDYVELSPL------TQGSPQRARTPART------LDRPAKQEELERDLAQRSEERRKWF
EATDSRA------TE-TPAGEA-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEVWRL
QGEAPQGAPRSQEDGHVPPGYISQEACERSLAEMESSHQQAMEELQRHHERELRRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRGFIASQGT-----GSGCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-----------------------------------------------------ELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRQGPKRWVE---------SQG-----
---PGRASWGGMPLPFPFYMSCSLSSPTN--------------------------ILSPP
LLWQDWDTVERQE-EA-PSWDELAVMIPRRPR-----EAPRADSSQRAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGQSAGQRWARLRGESGF-SLERRRSTLTQASS
MTPHSGPRSTMFQASP---AQRDTAQ-----------------------AASTCETPRAS
SPHRITQRDTSRASSTQQDTPRASST----------------------------------
------------------------------------QWNTPRASSPSRSTQQDNPRTSST
QQDNPQTSFPTCTPQRENPRIPCVQQDGPKASSPNRTTQRENSRTSCAQRDNSRASRASS
PSRA-TRDNPRTSCAQRDNPGASSPIRATQQDNPRISCAQRDNPGASSPNRTI--QRDSP
RTSCARRD----NPGASSPNRTTQRDSPRTSCAQRDIPRASSP--NRTIQQENPRTSCAR
RDNPRASSPIRATQQDNPRISCAQRDNPGAS----------------SPNRTIQRD----
--------------------------SPRTSCARRDNPGASSPNRTTQRDSPRTSCAQWD
IPRASSPNRTIQQENPRTSCARRDNPRASSPIRATQQDNPRISC----AQRDNPGASSPN
RTIQRDSPRTSCARRDNPGASSPNRTTQRDSPRTSCA----QWDIPRASSPNRT------
-----IQQENPRTSCARRDNPRASSPNRTIQRDSPRTSCTQRDIPRASSPNRTIQQENPR
TSCARRDNPRASSPNRTIQRDSPRTSCAQRDNLRASSPIRATQQNNPRTCIQQNIPRSSS
TQQDNPKTSCT-------------KRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTHSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTPSPVYPAACGA-------PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRAPESESPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQV-PEPSLLFQDLPRASTESLVPSMDSMHECPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLALSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSLGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQREPGPQAQCSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPS-Q
-----SQSQLLRRQSSPAPSRQVTKLPAKQ---AELTRWSQA--EPPHPRS-PEKRPEGD
RRLQGSPPPPRTSAKTPERELRTQ----------RPLESGQAGPKQPLGA----------
WQSQEEPPGSQGLHRHLER---SQEGGLG----PGGWWGCG--EPS----LGAAKAP---
--------QGTSGGTPREYRESW------------------GQPEAWEEKPT--------
-----HEL---------------PRELGKRSPLTSPPENWGGPEESSQSWHPGTPTAVGW
GAEGVCPYPHGSERRPELDWRDLLGLLRVPGEGAWAR---------LP--SLDWEGLLEL
L-------------QARLPCKDPAGHRDDPARA---------LGPELGPPGTKDVPEQG-
-SHSQPEGWA---EATPVNGH--SPALQSQSPV------------QLPRPACTSTQWPK-
--IKVTRGPVTETLAGLEQ-MGPLGSRSAAEGPSLPELQKDG--------------NPGA
PWRGAPQNGQGRL-SQGCPHPADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKYVLSW--------------------------------TGALR------EA
LTLASLSG----------------------------------------------------
------------------------------FLGA------------PEEEKWEEK-----
------------------------------------------------------------
------------------------------------------GETCQVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASGMDPGVLGCFEST-----LTGLQAWQGQDNLRSP---------
------L-SDVEALKRELQVLSEQYSQKCLEIGTL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVRGDFM---------
-----PSYLPPVPQDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTPDLLNFKKGWMSILDEPGE-----------------WRKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSECNKENTLHGYGSQKGSLKAGEQR-A-----------GPRKADGPRQA
LDYVELSPLTQGS------PQRARAPDR----------PAKQEELERDLAQRSEERRKWF
E--DSRAPE-------VPAGEG-----PRRSLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRGERR-PSDSH----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGETPQNACRSQEDGHVPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQG--------------PD
GLRKQHQ-SDVEALKRELQVLSERYSQKCLEIGAL-TRQAEEREDTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRSFIASQGT-----GNSCGRP-ERSSCELEVLLRVKENELQYLKK
EVQCLRDELQGMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKES
TRNSLAQ

-----------------------------------------------------ELRSPSG
TEVPYCDLPRCPPAPEDPLSASTSSCRSVVDPGLGPGPRRW---VEPQG------P----
GNGFMGWSLALSPGLECSGMI---SAHCN--------LC---LP---------GSRDSPA
SASGDWDTVERQE-EA-PSWDELAVMIRRRPQ-----EGPRADSSQKAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGQSAGQHWAKLRGENGF-SLERHRSTLTQASS
MTPHSGPRSTTPRASP---AQRDTAQAAST-----HET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASFTQRNTPRASSP------SRSTQQDNPRTSS-----
-----------------------------------NQQNNPKYSSPQKATQQDNPRTSST
QQDNPQSSFPTCTPQWDNPRTPCARRDDPRASSPNKATQRDNPRTSCAQQDDPRA---SS
PNRA-TRDNPRISCAQRDNPRASSPNRTTQQGNPRTSCAQRDNPRTFSQI--KAAQQDNP
RMS----CAQRDDPRASSPS----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
RATQRDNPRTSCAQRDDPRASSPSRATQKDNPRTSCA----QRDNPRASSPSRA------
-----TQRDNPRTSCAQRDDPRASSPNRTTQ------------------------RDNPR
TSCAQRDDPRASSPSRASQQDNPR-TSIQQ-----------------------NIPRSSS
TQQDKPKTSCT-------------KRDNLRPTRTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESESPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDAEHWCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHERPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQAQRSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAKQ---AELTWRSQA--EPPHSRS-PEKRPEGD
RWLQGSVPPPRTSARTPERELQTQ----------RPLKSGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG-----------------------AAKAL---
--------EGAWGGPPGEYR-E-----------------SWGQPEAWEEAAT--------
-----H--------EPPRELGKRS-------PLTSPPENWGGPTESSQSRHPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWAR---------LP--RLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPAPLPQSPA------------QSPSPACTSTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGS--TAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENTLHNYGTQKGPLKAGEQR---AGVEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSPG-

----------------------------------------------------QEPGNPPS
AEPPYCDLPRRPPASEDPPRSSASGCPSVVGPGLGPGLQRKARIKGPSAGSSAEVP----
TAASGSQSQELEAGPSLEDLASCLGGSFD--------EGLDSGTSSSPD--HDTPDDTSD
SSSVDWNTVARQE-EA-PSWDELTVMIPRKPQ-----EGPRADSARKAPSLLTRSPVGG-
DAAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DPCSGSRSAGQHWAKLRGESGHF-LEWHRSVLTQVSR
ATLPGGPRGASPQASS---LHRSAQKDAAQ------------------T-----------
----ASTQEKPRTSSTQQDIPRPAFTQHNTPRASSPSR------IAQRDDPRTSSVQRS-
------------------------------------------------------------
------------------------------------------------------------
------------------NLRVSSPTRTTKQDNSR-------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------TXPRDNSRTPC----------PQRD
NPRGASPNRTTPRDNSRTPCPQRDNPRGSSPNRTTPRDNSRAPC----PQQDNPRGASPN
RSTLRDNPRTPCPQRDNPRGASPSRTTPRDNSRT--------------------------
-------------PCPQRDNPRGASPNRSTQRDNSRTPCPQRDNPRGSSPNRTTQRDNPR
TPCPQRDNPRGASPSRTTPRDNPKASCIQQ-----------------------NNPRTSY
SQRDNPQS----------------------------------SSQRDSPGASSPRCCTKR
DHPGPSPPPRSAQQNNARNSSPHRTNKDIPWASFPLRPTQSEGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRPPQTSSPTRPAQRDPPLSSSGSAQHGSPSQAASSFHNPGPHSAS
RTSSPLYPATRGA-------PQTSSEPSQPPCSVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHASETELPHHTPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDTET--QSTQ
HDPPQLPPPVCIGYRDAPRASSPPRQP-PEPFLLFQDLPRASTESLVPSTDSLHEPPHMP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDLPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLPP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRGSAAPGETRHNLEREEYTMLADLPP
PRRLAQREPGP--QCSNGGRTRSPGRAEVERLFRQERRKSEAPGAFQARDEGRSQRPS-Q
-----GQSQLLRRQSSPALSREVTKPLAKQ---AEPARRSQV--EPCRPRS-PERRPEGD
RRLQGTSLPPRTSARTPERERRTE----------RPLESGRAGPRQPLGG----------
WRSQEGPPGTQGPHRHLERGCSSPQEGPG----LGDWQGLG--EPS----RGLARAP---
--------EGTWRGPLRESEESWEQEGGPT--------GHRGQAEAWEEPPG--------
-----NRFREAPDRPALRGWASLQELPSAHQTKSPPENSRVGPEEFLKSQRPEIPTTMGW
GAEGTRPPLHSPERRSELDWKDLVGLLGVPREGAWGRIEESMLTSHLP--RLDWEGLLEL
L-------------RAQLPRKDPAGHWGPPAPASG-GPPAPASGPEVGSPGTNGTLELE-
R-QGQPDGWE---ESTLVNGQSQSAGQWPGSSA------------QPPSPACTSTQWPK-
--TRVTRGPETSPMAGLEE-MGQLGSRSPAEGPSLPEWEFQSEEPEES------------
----EPSKGQDSLTDQKHADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTTAPDVTKLSDCNKENALHGYSTQKGSLKAGEQR---GGSEVIGRG-GPRKADGQRQA
LDYVELSPL------TQGAPQRVRGPART------LDRPAKQEELERDLAQRSEERRKWF
EATDGRP------PE-TAAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPGDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGEVPQGAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMAELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVAALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFIASQGT-----GDGCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMLQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLATAALQEKES
MRNSLAE

-MEEVPGDA-PCEHFEANML-----------TQNRRQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDLLSASTSGCRSVVDPGFGPGPRRG---PFPSAGLPEEGP----
TAAPRSRSHDLEAVPYLEGLTTSLRGSCN--------KDPGSDPGSSPDSDSATPDDTSN
SSSVDWDTVERQE-EA-QSWDKLAVMIPRRPQ-----EGPRADSSQKAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWAKLRGESGFFSLERHRSTLTQASS
MTPHSGPRSTTPRASP---AQRDTAQAAST-----RET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASFTQA-----SSP------SRSTQQDNPRTSS-----
-----------------------------------NQQNNPQYSSPQRATQQDNPRTSST
QQDNPQSSFPTCTPQWDNPRTPCARRDDPRASSPNRATQRDNPRTSCAQRDDPRA---SS
PNRV-TRDNPRISCAQRDNPRASSPNRTTQQDNPRTSCAQRDNPRTFSQI--KATQQDNP
RMS----CAQRDDPRASSPSR---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------ATQRDNPRTSC----AQRDNPRASSPN
RTTQGDNPRTSCAQRDDIRASSPSRATEQDNPRTSCA----QRDNPRAFSPNRT------
-----TQRDNPRTYCAQRDNPRASSPNRTTQ------------------------RDNPR
TSCAQRDNPRASSPNRASQQDNPR-TSIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KWDNLRPTRTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESESPHHEPPYIPPAVCIGHRDAPQASSPPRHTQYDPFPFLPDTSDAEHRCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHERPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQAQRSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGQSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKHPAKQ---AELTWRSQA--EPPRSRS-PEKRSEGD
RRLQGSPPPPRTSARTPERELQTQ----------RPLESGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG-----------------------TAKAL---
--------EGAWGGPPGEYR-E-----------------TWGQPEAWEEAAT--------
-----H--------EPPRELGKRS-------PLTSPRENWGGPTESSQSRRPGTPTTVGW
GAEGARPYPHGPERRPELDWRDLLGLLRAPGDGAWAR---------LP--RLDWEGLLEL
L-------------QARLPHKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPALRPQSPA------------QPPSPACASTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGS--TAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLSDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHNYGTQKGPLKAGEQR---AGVEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQHRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPASDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDMEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MEDVAGNV-PCERFEANVL-----------TQSRCQNCFHPEEAHG--ARHQELRSPSS
AEVPYCDLPRCPPAPEDPLSTSISGCQSVGDLGLRPGPKRG---LSTSAGLPKEGP----
TAAPRNRSWELEAVPYLEDLTSSPCGSCN--------EGPNSDASSSPD--CDTPDGTSD
SSSVDWDAVKRRE-ET-PSWDKLTTMIPRRLQ-----EGPRADSAQRAPSLPTRSPAGG-
DTAAQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DAGGGSRSAGQHWAKLRGESGYFSLERHRAALTPASS
MTPQSRPQSATPQASS---AQRDIAQAFSTQ----RST------------------PRAS
SPARITQRDNPRTSSTQQDTPRASQYS---PRASSP------SRMTQRDNPRTLSTQRN-
---------------------------------------NPQLSSPPRATQQDNPRTSSA
QQDNPQSSFPACTPKRENPRASYAQRDNPRSSSPNRTTQRELFLASYAQRDNPRS---SS
PNRTTQRETPRTFCAQQHNPRSSSPNRTTQWENSRKSCTQRDNPRALSPNRT--------
------------------------------------------------TQQENPRKSCAQ
RDNPRSSSPNR-------------------------------------------------
-------------------------------TTQQENPR----KSC----------AQRN
NPRASSPNRTTQQENPRTSCAQQDNPRASSPNRITQRENSRTSC----AQRNNPRASSPN
RTTQQENPRTSCAQQDNPRASSPNRTTQRENPRTFCA----QQDNPRSSSPNRT------
-----TQWENSRKSCTQRDNPRASSPNRTTQQENPRTFCAQQDNPRSSFPNRTTQRDNSR
TSCAQRDNPRASSPNRTAQRDNSRTSCIQK-----------------------NTPRSSS
TQRDNPKTSYT-------------KWDNLRTACTQRDNPRASSFKRDNPRTSSPQCCTQK
DNPRPSSPHRSAQRNNPRPSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPTRPARCDPPQS-SGPTQHNSLSRATSSSHNPGQQSAS
RTSSPLHPAPQAA-------PQTSPEPSQPACAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRAPESESPHHDPPYVPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDASE-NQSPQ
HEPPQFPPPVCIGYRDAPRASSPPRQA-PEHSLLFQDLPRASTESLVPSTDSLHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQREPGPQAQCSNGGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRLQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKPPAKQ---AEPARRSRA--EPPHHRS-PERQSEGD
RRLQGSSLSPRISARPPEREPRTE----------RPPESGRAGPRQPLGG----------
WQSQEELPGSRCPHRPRERSWSGQE-GRG----PGGWQGRG--EPN----LGAARAS---
--------EDSWRGPPRECR-E-----------------SWGQSEAWGEPPK--------
-----E--------PARRAWGSL---------QDPPENSWAGPAEFSHPRQPEPATAMDW
GAEGACPHPHGPERQPELDWTDLLGLLRAPGEGTWAR---------LP--RLDWEGLLEL
L-------------QARLPHKDPAGRRGDPAKA---------SGPEPGTPDTKGALEQE-
QHS-QPEGWV---EATIVNGH--SPE--------------------LPSPAYTSTQWPK-
--TKVTGGPETSTVA-------------SPRRPSLPELEFQPEEPEDS------------
----EPSRGQDFLTEQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSPSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPASAPDVTKLSDCNKENSPHSYGTQKGPLKAGEQR---ACSEVIGRG-GPRKADGQRQS
LDYVELSPL------TQGSPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERHGPSSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRSLEDGHTPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFIASQ-------GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQTMQKDKRFASGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKQS
VRNSLAE

--------W-SCEQGEGVTLLPTQGTAWATAAVPVAGLQGPQGDSHQ--ACSQEPHSPSS
AEPPYCDLPCCPLAPEDPLGTTTCAGHSVEGLG--LRQGPQR-GWSPTAALPAEGP----
ATAPRNRYQDPEVVPYLEEP--------------------NSDTSSSQD--SNTPHDTSN
SSSV--DTVERPG-VV-PNGDRLNVMILRRPQ-----EGLRADSAQRI----TRSPARG-
DPEGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DSGSGGQSAGQHWAKLRAESGYFSLERHRSGKTQASS
GTPPSGPRTTN-QASS---AQRGVFQNASAQ-----------------------ETSQAS
SIPPNAQRDTPRTL----------ATQRSGPRI---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------PH-------------------------------
-------------------------------VVSSPCVQASSLNRTTQRDNPRTPCAQRD
NPRSSCA------------Q--RDNPRSSSPSRTTQRDNPRIPC----AQRDNPRSSSPS
RTTQRDNPRT--------------------------------------------------
-------------PCAQRD--------------NPRTPCTQRDNPRSSSPNRTTQKDNSR
TFCI------------------------VQ-----------------------NTPRTPS
TQGNKTSASCS-------------RWEHLRSACTQRDNPGPPPF---------SQGCTQK
DNPGLSSPRHATQGSSSRNPSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRTKQN
QVPWASISLRPTQGDRT-QTSAPTKLAHHDPPQHSLPSL----A----SSSHNPGHPSAS
RTSSPLHPAPRGV-------PQTPSEPSQPSCAVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDAEN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEP--FFQDLPRASTESLVPSTDSLHEPPHIP
PPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSIDSLRGSPLLLP--QVCI
GHRDAPRASSPPRHPPSDLGLLAPSPPPGSS-GSRGSAPPGETRHNLEREEYTMLADLPP
PRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDKGRSQRPS-Q
-----GQSQL-RRQSSPVPSRQVTKPSTKQ---VEPAR---T--EAPHPKS-PEKRPEGD
RWLQRSSAPARTSARPPERKAQTE----------IHLESGCTGLRQPLGG----------
WQSQEELSGPQSPNRHTEKSWDSQEEGPG----LGGWPELG--SSS----------L---
--------EGIWRGPPQEHRERW------------------GQSETWKQLSS--------
-----NGLQGR----PPTGQGSLQELSRPHQPTTPRDSSWAGPTECLCTLHPEATAGMGW
RAEGASPHQDSLEKPPDLDWRDLLGLLRASEDGAWAR---------LP--RLDWEGLLEL
L-------------QARLPQRHPAGHLRDPARA---------SGPELGSSGTDDTLKTE-
-TQTQTEGWA---KATQANGH--SPGQQSESPA------------QVPSSACTSTQWPT-
--TKVTSGPATL--SALEQ-TDHLGSHSP------PDQAFQPEEPEGS------------
----EPSRGEDSLADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PALF
NPY------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGCGTQKGSLKIGEQR---TGSEVIGRG-GPRRVDGSRQS
LDYVELSPL------TPSSPQRVRTLTRST-----SERPPKQEDLERDLAQRSEERRKWF
ESTDSRN------PE-TPSGDG-----PRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNHGRSERRGPPNDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRLQENSHIPPGYISQEACERSLAEMESSHRHVMDQLQQHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-NRELSKTRSLQQGPDG-------------
-LQKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TQQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVMHKDKRFT-GKYQDAYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDYNKENTLHGYGPQKGSLKVGEQR-AGS--EVGGRS-GTRKVDGHRQS
LDYVELSPLTQGG------PQRART-------------PAKQEELERDLAQRSEERRKWF
EATDSRAPE-------T--GEA-----PRRALGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRSERRAAPSDT----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRV
RGEAPQNVPRSQEDSHIPPGYISQEACERGLAEMESSHQQAMEQLQRHHERELQRLQQEK
-EQLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQG--------------PD
GLRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHKLRRCQQEGQELLRH
NQELHAHLSEEIDQLRSFMASKGT-----SDSCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQTMQKDKRFTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAMAALQEKEA
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MGGWKR----------------------------LGP
RRGR----E--GLALRRRRRV-----AERGSG--------------GGV-------PLH-
--------------------------------------------------------PLLL
-SRVPDLLNFKKGWMSILDERGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVHTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLLDCNKENILHGHGPQKGSLKAGEQR-AGS--EVSGRS-GPRKVDGPRQS
LDYVELSPLTQGS------PQRPRT-------------QARQEELERDLAQRSEERRKWF
EATDRRALE-------TPTGEA-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRSERRAPSSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEACRV
RGEAPQNAPRPQEDGHIPPGYISQEACKRGLAEMESSHQQAMEQLQRHHERELQRLRQEK
-EQLLAEETA---ATASAIEAMKKAHQEEL-SRELSKTRSFHQS--------------PD
DLQKQHQ-SDVKALKWELQKLSEQYSRKCLEIGAL-KQQAEERELKLQRCQQEGQELLRH
NEKLHACLSEEIERLRSFMASKGT-----SNSYGRGGERSSCELEVLLRVKENELQYLKK
EAQCLRDELQTMQKDKCFTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAVAALREKEA
ARDSPAE

-MEGVAGNA-PCDHFEANVL-----------AQRCCQNCFHPEEAHR--ARHQEPGSPPS
AEAPYCDLPRRPAAPEDPLGASTSNCQSVVGSGLGPGPERG---P--STGLPAEGL----
TATP--RSQEPEAAPYLEGLASSLCGNFN--------ESPDSGTSSSPD--CEAPDDTSD
SSSVXXXXXXXXXXXX-XXXXXXXXXXXXXX-------------------XX-----XX-
XX---XXX----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--XX--------------------------------------------------------
--------------------------------------------------------XXXX
-------XXXXXXXXXXXXXXXXXSGGGNRSAGQHWAKLRGESAYF-LERHRSALTPVSP
ATPQSGARSTTPQASS---LHRSASTQL--------------------------DTSRAS
SPPRLAQRDNPRTSSTQQDTPRTSSTQRNTPRASSPSR------VAQRDNPRTSSTQ---
------------------------------------------------------------
-QDTP--------------RASSTQQNTPRPSSPSRVAQRDNPRTSSIQQDTPRA-----
------------SSTQRNAPRPSSPSRVAQRDNPRTSSTQQDTPKT--------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SS----------TQRN
APRASSPSRVAQRDNPRTSSTQQDTPKTSS------------------------------
-------------TSGTPRASSPSRVAQRDNPRTSS------------------------
-----TQQDTPRASSTQQNTPRASSPSRVAQRDNPRTSSTQRNNPQVSFPPRATQQDNSR
ASSTQQDSPQAPVPTCTHQRDNPRPSCIQQ-----------------------NTPRTSS
TQRDNPKTSCA-------------QRD----------NPKSSSSRRENPGSSSSQGCTQR
DNPGPSSPRRSSQRNNPRNSSPHRTNKDIPWASFPLRPTQGDGPRT-----SSPSRSKQS
EVPWASIALRPTQSDRP-QTSSPIRPAQRDSPQRSSSPTQHNSPSRATSSSHPPSHHSAS
RTSSPLHPATRGA-------PQTSPEPSQPPCPVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHASESESPHHDPPYMPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEN--QSAQ
HEPPQFPPTVCIGHRDAPRASSPPRQA-PEPALLFQDLPRASTESLVPSTDSLHERLHIP
SPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPTGTS------------------
-----------------------------------MESLAPSTDSLRGSPVLPP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQREPGP--QCSNGGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPS-Q
-----VQSQPLRRQSSPALSREVTKPLAKQ----EPARRSRA--EPPHPRS-PERRPEGE
RRLQGSSPPPRTSVRT-EREQRTE----------SPLERGRAGPRQPLGG----------
QQSLEGPPGSGDPHGHLERGWGRQE-GPG----LGGWLGLG--GPR----QGAARAP---
--------EETWRGPPRESE-E-----------------SWGQAEAWEEPPS--------
-----H--------EPSGRPGRSCP------VMRPPESSRAGPGEFSKPQRPETTPATGW
GAEGACPNLRGPERQPELDWRDLVGLLMAPREGAWTH---------LP--RLDWEGLLEL
L-------------QAQLPRRDSAGHWGGPGTI---------SPGT-----GTLELEPE-
-RHTQSEGGA---GATLVNGY--SPGQWPQSSA------------QPPSPAGISTQWPK-
--TKVTSGPETSTMAGLEE-TGQLRGRSPAEGPSSLQWEFQSKEPEES------------
----EGSRGQDSLTDQKQADSADKRPAEGKAESPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPR----TPSLTTISPSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRCCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHSYGTPKGSLKAGEQR---AGSEVIGWG-GPRKADGQRQS
LDYVELSPL------TQGSLQRARTPARA------LDRPAKQEELERDLAQRSEERRKWF
QATDSRA------TE-TQAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRRERRGAPSDS----------------------------------
----------------------------------------HEALEREVQSLRAQLEAWRL
QGEAPHGAPKSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTQSLPQGPDG-------------
-LQKQHQ-SDLEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFIASQGT-----GNGCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDRRFTSGKYQDVYVEL-HIKTRSEREIEQLIEHLRLAMDALEMM--
PRNSLTE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LQPDLLNFKKGWMSILDKPGE-----------------WKKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAIFTLSAMTSGIRRNWIEALRKNV
RPVSAPDVTKLSDCNKENTIRNCVPPKSSLRVDEQQQ--PSSEGSTKG-STWRADGPHHA
FDYVELSPLQQDT-QNQGSPPRTRGSLRV-----SERVSKH-EDLERDLAVRSEERRKWF
ESPDSRVSNSDGLGGTLSRKVE-----EPDLPAAPLSEEQRVRLNEEIEKKWLELERLPL
KDSRRVPLTTLLNQGKGNHGDA-NEALKKEVRALWKVVFCTIPAALCLPGGSAEEQAHRC
RWHHLHGAVFPGSAFAISCLQLFPSQQTHHLPALGKRLSISLLSLAQVQSLRAQLESCRA
RNESLREAAKSQGDGHVPRGYISQVSRMGE---PQAGKCQSLDSLPSRYR----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------

-MEQGAGHA-PCAHFEADMP-----------AQSCCPNCCHPEEVPG--ARHQEPRSPPR
AEAPYCDLPRRPSAPEDLFGALTSCCQSVVGPDLGLGSDRG-----PSAGRPEEGP----
AAVPRGRSRELEAAPCLEGLPISPCGSRS--------EGPDLATSSRLD--CDTPDETSS
SSSVDWDLDQRQV-EA-PTSDELPVMIPRRPQ-----EGPRADSARRAPSLLTRSPGGG-
DTAGQRKEERTGGRGAGGR------EWKYHLGDDR---------------LVMEGKAASG
GRAGRQHPSQAAAR--VGKRASCAPRHAAENIAPASNLRKHPN----RGSLCKIT-----
-------------GLGSLRKTKQGWETSKLKEAAE-----TGLARSASLT-------RSQ
SSYPVISSSCRISPKSSAVLVGSPPAAHPTSVPFLPPPLRPPSHRYTSQDCCPSPHVPPR
FCPGPPSAHSPSSSGSLSQEGSWSPSQRRPPLDLR-NQRRPPLCPLGSWSLNCSGQPRPR
RSS--------P------ASTMLGTPPG---------DLL--ANDSPLGRHRPVPAQAAS
TAPQSGPQSATPQAPS---PLRSAQRDVAQ------------------AASTQRDNPRAS
SPPRTTRQDNSRTSSTQWDTPRA----------SSPSR------TTQR------------
--------------------------------------NGPRVSSPPRNTQ---------
-QDKPRTSSPSHTPQRGNPRTPLNQRDNPRASSPNRATQR--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------DNPRASSPNQATQRDNPRTPCVQKD
NPRASSPNRATQRDNPRMSCVQKDNPRASSPNRATQWDNPRTSC----VQKDNPRASSAN
RATQWDNPRTSCIQKDNPRASSANRATQWDNPRTSCI----QKDNPRASSANRA------
-----TQRDNPRTSCAQHDNLRASSPNRATQWDNPRTSCIQKDNPRTSSPKRAIQPDNPR
TSCAQRDNPRASSPNRATQWDNPRTFCAQP-----------------------STPRTSS
TQQDNPKPSCA-------------QRDNLRTSCSQRENPHSSPLQRDPPGSSSPQCCTQK
DNPGSSPPHRSTQQSNPRNSSPHRTNKDIPWASFPLWPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPTRPAQRDPPQP-SGPTQHNSPSRVTTFSHNPGHHGAS
RTPSSLHSTTWGA-------LQTSSEPPQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRASESESPHHEPPYIPPAVCIGHRDAPRASSPPRHSQFDPFPFLPDTSDAEA--QAPQ
HEPPQLPPPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSTDSVHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLPP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
PRRLAQREPGPQAQRSSGGRTRSPGRAEVERLFGQERRKSEAPGALQARDEGRSLRPG-Q
-----GQSQLLRRQSSPALSREAAKPPPKQ---AEPARRSPA--EPPHPRS-PERHPKGH
RRLQGSSPSLSTSARTPERELRME----------RL--PGRPGPRQPPGG----------
WLSPEEPSGSQGPHRHLERDWSSQHGAPG----PRGWRGRG--EPS----REAARAP---
--------EGTRRGPPGASEES-----------------GWRGSEAWEELPR--------
-----NRLRE---------------PLHPHRPSTPPESPWGGPAESSQSRQPDT-ANSGW
GAEGTCSTLRTSERQTELDWRGLVALLQAPGQGAWARTEEPLLSSCLP--RLDWEGLLEL
L-------------QARLPCKDPAGHWGA-------------SGPEQGTPGTKGALEQE-
-GHNQPEGLA---EATLVNGH--SPGQWPQSQA------------QPPSPADTSTQWPK-
--TKVTSGPETSTMAVLEE-TGQLGSRSPAEGPRLPEGEFQPEEPEKS------------
----QQSKGQDSVTGQEQADSADKRPAEGKAGSPLKGRLVTSWRMPGDQ-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----HPGSPEVTPSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDTVHTLSAMTSGIRRNWIEALRKTV
RP-SAPDVTKLLDRNKENTLHSH--PKGSLKAGEQR---AGSEVISRG-GPRKVDGQRQS
LDYVELSPL------TQGSQQRARTPARA------PDRLAKQEELERDLAQRSEERRKWF
EATDGRA------TE-TAAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLAALLNQSHRERRGPMSDS----------------------------------
----------------------------------------QEALEKEVQSLRAQLEAWRL
RGEAPRDTPGSQEDGHTPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-TRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAAEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRSFISSQGT-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVMQKDKPFAPGKYQDVSVELNHLKTRSEREIEQLKEHLRLAMAALQEKEA
LRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------Q-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDYNKENALHSYGTQKGSLKAGEQR---AGSEVIGRG-GPRKAEGQRQS
PDYVELSPL------TQSSPQRARPLARA------PDRPAKREELERDLAQRSEERRKWF
EATDSRA------IE-TPSGEG-----PRRTLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRSERRGPSNDS----------------------------------
----------------------------------------HEALEKEVQCLRAQLEAWRL
RGEAPQDAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELNKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHTHLSEEIDRLRSFIASQGT-----GNGCGRSSERSSCELEVS-------------
------------------------------------------------------------
-------

-MEGVAGNA-PCECLEANLR-----------AQSCCQNHFHPGEAHR--ARHQEPGSPPS
AEVPYCDLPRRPPASEDPVSPSTSSCQSVLGLGLGLGPGPE---RGPSAGSSTEVP----
TVAPKSRSQEPKAVPYLEGLASSQSGSFD--------EGPDSGTSSSPD--CDTPDDTSD
LSSVDWDIVTRQE-EA-PSWDELTTMIPRKPQ-----EGPRADSARRAPSLLTRSPVGG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTCSGSRSAGQHWAKLRGESGHF-LERHWSALTQASC
ATPQSGPRSATPQVSS---LHHSA------Q----RDAAQ--------TASTQFNTPRTS
SPTQIAQRDKPRTSSIQQDIPRTSFTQRNTPRASSPSR------VAQRDNPRTSSIQRNN
----------------------------------------PRVSSPTRAIQQDNFRTSSI
QQDNPQTSFSTCTPQRDNPR----------TSSPNRTAQRDNPRTSCTQRD---------
------------------NPRASSPNRTTQWDNPRSSSPN--------------------
------RT----------------------------------------AQRDNPRTSCTQ
RDNPRASSPNRIT-----------------------------------------------
---------------------------------QRGKPR----TSC----------TQQD
KPRGSSPNRTTQQENPRTSCVQRDKPRTPSPNRTTQRDNPRTSC----TQQDNPRASSPN
RTTQQENPRTSCVQRDKPRAPSPNRTTQRDNPRTSCT----QQDNPRASSPNRT------
-----TQQENPRTSCVQRDKPRAPSPNRTTQRDNPRTSCTQQDNPRASSPSRTTQRDNPR
TSCAHRDNPRASSPNRTTQRENPRTSCIQQ-----------------------NIPRTPS
TQRDNPKTSCT-------------QWNNPRTSYTQRNNPQSS-SRRDNPGTSSPRCCTQQ
DNPGPSSPHRPTQRNNPRNSSPHRTNKDIPWASFPLRPIQSEGPRT-----SSPSRSKQS
EVPWASITLRPTQGDKP-QTSSPTRPAQRDPPLSSSGSTQHNSPSRATSSSHNPGHHSAS
RTSSPLYLATHGA-------PQTSSEPSQPACSVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHASESELPHHTPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAET--QSPQ
HDPPQFPPPVCIGYRDAPRASSPPRQP-PEPSLLFQDLPRASTESLVPSTDSLHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPMLLP--QVCI
GYRDAPRATSPPRHPPSDLAFLAPSPPPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQREPGP--QCSNGGRTRSPGRAEVERLFGQERRKSEAPGTFQARDEGRSQRPS-Q
-----GQSQLLRRQSSPALSREVTKPLVKQ---AGPARRTQA--EPSPPRS-PERRPEGD
RRLQGSSLPPRTSARIPEKEQRRE----------RPLESGQEGPRQPLGG----------
WQSQEEPPGTQGPHRPLESACGSRREGPG----LEGWQGLG--EPS----RGVAIAP---
--------EGTWRGPLRESEESWGQPGGPT--------GLRGQPEAWEEPSS--------
-----N--------ELPS----------APQPQSPPEDSRVGPVEFLKSQRPETPTTTGW
GAEGTCPHLHSPERRPELDWRDLVGLLGAPREGAWAHTEESTLASHLP--RLHWEGLLEL
L-------------QAQLPRRDPAGHWGALATA---------SGPEVGSSGTNGTLELG-
R-QGQPDGWM---EATLVNGQ--SAGQWPQSSA------------QQPSPAIISTQWPN-
--TKVTSGPETSTMAGLEE-MGQLGSRSPAERPSLPEWELQSEEPEES------------
----EPSKGQDSLTDQKQADSADKRPAEGKHGSPPKGRLVGAWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEES---PPPLLTATSPSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYSTQKGSLKAGEQR---GCSEVISRG-SPRKTDGQRQS
LDYVELSPL------TQGSPQRARTPART------LDRPAKQEELERDLAQRSEERRKWF
EATDSRP------VD-TAAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPSGDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGEVPQSAHRSQEDSHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVAALKRELQVLSEQYSQKCLEIGAL-MRQAEEREHTLRRCQQEGQELLRH
NQELHTCLSEEIDRLRGFIASQGT-----GDSCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMLQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYGPQKGFLKAGEQR-AGS--EVGGRS-GPRKADGPRQS
LDYVELSPLTQGG------PQRACT-------------PAKQEELERDLAQRSEERRKWF
EATDSRAPE-------T--GEA-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNRRVPLTALLNQGRSERRAPPSNT----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRV
RGEAPQSTPRPPEDSHIPPGYISQEACERGLAEMESSHQQAMEQLQRHHERELQRLQQEK
-EQLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQG--------------PD
GLRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHKLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFVASKGT-----SNSCGRGSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQTMQKDKRFTSGKYQDVYVELNHIKTRSEQEIEQLKEHLRLAMAALQEKEG
TRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
-LSQPDLLNFKKGWMSLLDANGE-----------------WKKHWFVLTDSSLKYYRDSN
AEEADELDGEIDLRTCTNVPEFAVQRNYGFQIHTREGVFTLSAMTSGIRRNWIEALRKNV
HPVSIPDVTKLSESNKENTFVPPRNT--TNRPEELR-LGS--EVKHRK--VEFTGTRHSS
FDYVELSPLSPGD----------------------------------ERDQRLEERRRWF
EAPPIGETH-------TA-----------RRVPQVLTEEQKQKANEEIEAKWKELERLPL
RDSKQTPLTCLLGGGRNK----LGDS----------------------------------
----------------------------------------DGALEKQIQSLKLQLEKAKR
EL------ESQKSGSAVPSGYISQEACERSLSQMEASHQQLMSELQRHHEWEIQRLRQEK
-EQLLAEEAA---ATASVIESIRNAHKEEL-QREVEKARSFQHGGSA----------SQD
LLRRQNQ-SEMVSVRRELQALSERYSQKCLEISAL-NQAGEEREKELQRCQTEGQELLKQ
NQELNKRLSEEIGKLRSLTASNGP-----SDGT-RQGEKNSTELEVLLRVKDNELQYLQK
EISCLREDLENMQKDKRYASEKYKDIYMELNNIKSRSEREIDQLKEHLRLAMAALREEAA
LRNSVGE

--------------------------------------------------CSQEPGRPES
AEVPYCDLPRRRPAPEDSLGTPTSSCQSVVGPGRGPEPERG---P--PAGLLAEGF----
TAAS--RSREPEAAPYLEGLASSPCGSFN--------ESPDSGT-------SEAPDDTSD
SSLVDWDTVERRE-EA-PSGDNFTMMIPRKSQ-----EVPRADGARKAPPLLTQSPVGGG
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------GSGVGNRSAGQHWAKLRGESGYFSLERSQSVPTPASP
ATPQSGPRSATSQASS---LHRSAPRTLSAQ----QDAPK--------TSSSPRDTPRAT
SPSRAAPRDNLRTLSAQQDAPKTSSTQ---------------------------------
------------------------------------------------------------
-------------------------RNTPRATSPSRAAPRDNLRTSSTQQDAPK------
-----------TSSTQRNTPRATSPSRVVPRDNLRTSSTQQDTPK---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------TSSTQRNTPRATSPSRVVPRDN---------------------
-----DAPKTSSTQRNTPRATSPSRVVPRDNLRTSS------------------------
-----TQQDTPKTSSTQRNTPRATSPSRVVPRDSPRTSSTQRNNPWVSSPPRATQQDTSR
ASY--------------TQQGNPRPSCVPQ-----------------------NTPRSSS
AQRDNPKTSCT-------------QQD----------NPQFSSSRRGNPGSTSCQGCTQQ
DHPRASSPHRSSQRNNPRNASPHRTNKDIPWASFPLRPTQSDGPRS-----SSPSRSKQS
EVPWASIALRPTQSDRP-QTSSPARSAQRDSPQSSSGPTQHNSPFRATATSHNPGHHGAS
RTSSPLHPTPRGA-------PQISSEPPQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHASESESPHHDPPYMPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDA-E-NQSPQ
HDPPQFPPPVCIGYRDAPRASSPPRQA-PEPSLLFPDLPRASTESLVPSMDSLHEPPAIP
APVC-------IGHRDAPSFSSPPRQP-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLRGSPVLPP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPPPGSSGGSWGSAPPGEIRHNLEREEYTVLADLPP
ARRLAQREPGPQG--SNGGRTRSPGRAEVERLFGQERRKSEAPGAFQAQDEGRSQWPS-Q
-----GQSQLLRRQSSPGLSREVTKSPAKQ---AEPARRSRT--EAPHPRS-PERRPEGD
RWLQGSSPPLRMSARTPEREQRTQ----------RPLERGRVGPRQPLGG----------
WRSQEEPPGSQGPHRCLERGWRSQEEGPG----LGGWQGLG--ESS----RGAARAP---
--------EAMWRGLPRESE-SWSLLGGLS--------GHRWQSETWEEPLD--------
-----------------RGWGSLQELSSPHQPVTPPENSRAGPGEFSKSQRPETLPAMGR
GTEGACPHLHGSERRPEFDWRDLVSLLGVPREGTWSRSEEPTLTSHLP--RLDWEGLLEL
L-------------QAQLLHKDPAGHWVGPGQA---------SPGTK----GTQELEQD-
QHS-QPEGGA---GAALVNGY--DPGQWPQSSA------------QPSSPTSISTQWPK-
--TKVTSGPESSATTGLEE-TSQLGSRSPAEDPSLPQREFQSKEPEES------------
----ERSRGQDSLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHSYGTPKGSLKAGEQR---VGSEVISRG-GPRKADGQRQL
LDYVELSPL------TQGSPQRARTPART------LDRPAKQEELERDLAQRSEERRKWF
EATDSRA------TE-TPAGEG-----PRRVLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGRGERRGAPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGEAPQGAPKSQEDGHIPPGYISQEACERSLAEMESSHQQVMQELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELNKTRTLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRSFIASQGT-----GNGCGRSSERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-MEEVPGDA-PCEHFEANML-----------TQNRRQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCRSVVDPGLGPGSRRG---PSPSAGLPEEGP----
TAAPRSRSHDLEAVPYLEGLTTSLRGSCN--------EDPGSDPGSSAD--SATPDDTSN
SSSVDWDTVERQE-EA-PNSDELAVMIPRRPQ-----EGPKADSSQKAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGWSAGQHWAKLRGESGFFSLERHRSTLTQAAS
MTPHSGPRSTTPRASP---AQRDTAQAAAT-----RET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASFTQRNTPRASSP------SRSTQQDNPRTSS-----
-----------------------------------NQQNNPQYPSPQRATQQDNPRTSST
QQDNPQTSFPTCTPQWDNPRTPCARQDDPRASSPNRATQRDNPRTSCVQRD---------
------------------------------------------NPRASSPV--RASQQDNP
RTS----CAQRDNPRTSSPDRT--------------------------T-RDNPRTSCAQ
RDDPRAFSPNRARR-DNPRISCAQQDNPRTSSPN--RTTQRDNPRTS----CVQRDDPRT
-------------------------SSPNRTT-QRDNPR----TSC----------AQRD
NPRTSSPDRTT-------------------------RDNPRTSC----AQRDNPRTSSPN
RTTQRDNPRTSCVQRDDPRTSSPDRT-TRDNPRTSCA----QRDNPRASSPDRT------
------TRDNPRTSCVQRDNPRASSPNRTTQ------------------------RDNPR
TSCVQRDNPRASSPNRASQQDNPR-TSIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KWDNLRPTHTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSSHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRVTSSSPNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESELPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDAEHRCQSLQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEGPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSLVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSRGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQAQHSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAKQ---AELTWRSQA--EPPHSRS-PEKRPEGD
RQLQGSPSPPRTSARTPERELQTQ----------RPLESGQAGPRQPLGA----------
WQSQEEAPGSQGPHRHLERSWSSQEGGLG-----------------------AAKAL---
--------EGAWGGPPGEYR-E-----------------SWGQPEAWEEAAT--------
-----H--------EPPRELGKRS-------PLTSPPENWGGPTESSQSRRPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWAR---------LP--RLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPAPRPQSPA------------QPPSPACTSTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGSRSTAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHNYGTQKGPLKAGEQR---AGIEVVSRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----PDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHNYGTQKGPLKAGEQR---AGVEVVSRG-GPRKADGQRQA
LDYVELSPL------TQAPLQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCRRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MERAAGNA-PCEHFEAN----------------VCQNCFHPEEAHR--ARHQEPRSPPG
AEAPYCDLPRCRPACEDPLSASASGCQSVVGLGLGPGPERG-----PSAGLPAEGP----
TAHPRSRSGDPEAVPYLEGLVSSLCDSFD--------ESPDSSASCSPD--CDAPDDTSN
SSSVDWDIIEKQE-EA-PSWDKLAVMIPRKLQ-----EGPRADSARKAPSLLTRSPVGG-
DPAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DIGGGSRSAGQHWAKLRGESGHF-LERHRSAPTQASS
ATPQSGPRSTAPQASS---LRRSAQS----------NVAQ--------ATCTQLSTSRAS
SPPHTAQRDNSQTASSQQDTPRASPTQRNSPRASSPPR------GAPRDNPRTSSTQRSN
----------------------------------------YRVPSSPRDTRQDNSRTSST
SQDDAQTSFPTYSPQRESSRT---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SC----------APRD
NPRTASPNRTTQRESARTSCAPRDNPRTASPNRTTQRESSRTSC----APRDNPRTASPN
RTTQRESSRTSCAPRDTPGAASPTSTQRXXXXXXXXX-----------------------
------------------------------------------------------------
----------------------------XX-----------------------XXXXXX-
-XXXXXXXXXX-------------XXXXXXXXXXXXXXXHPSSFRRDNPGTSS-HCSTRQ
NNPGPSSPRRSTQQNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRS-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPTRPAQRDPLQSSSTPTQHHSPTQATSSSHSPGRHSAS
RTSSPLYPATHGA-------SQTSFESSQPSWAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHASESESPRHEPPYIPPTVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEN--QSPQ
HDPPQFPPPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVRSTDSLHEPPYIS
NPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLPP--QVCI
GHRDAPRASSPPRHPPSDLALLATSPLPSSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRKPGP--QCSNGGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQRPS-Q
-----GQSQLLRRQSSPALGREVTTPLAKQ---AEPAR-SRA--EPPHPRS-PKRQPEGD
RRFQGSSPPPRTSARTSERERRTE----------RPPESGWAGPRRPLRA----------
WQSQEELPGSWGPHRHLERGWNSQEEGPG----LGGWQELR--EPS----QGAVRAP---
--------EGTCRGPPRESEESW------------------GRSEASVESPS--------
-----NGLQESPDRPAQRGQP-----------M-SSPNCGEGPAEFSKSWKPETLTAVGW
GTEGACPHLHGPERRPGLDWRDLLSLLGVPRVGASAY---------LP--RLNWEGLLEL
L-------------QAQLPRKDPAGHWGSPTTA---------SGPELASPGTKDALKQE-
QHS-QPEGWT---EPVLVNGH--GPGQWPQSVA------------QPPSPACTSTQWPK-
--TKVTSGPETSIMAGPEE-QGHLGSRSPAQGPSSSVWEFQSEEPEES------------
----EPRGGQDSVTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPP-----SPLLTASPSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRCCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHSYSTQKGSLKVGEQR---MGSEVIGRS-GLRKADGQRPS
LDYVELSPL------TQGSPQRARTPART------LDRPAKQEELERDLAQRSEERRKWF
ESVDSKA------TE-TPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEVWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDMEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRGFIASQGT-----GNGCGRS-ERSSCELEVLLRVKENELQYLKK
EVQCLRDELQRMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
TRNSVAE

----------MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQ--ACSQEPHSPPS
AEAPYCDLPRCPPALQDPLHTTTCVGQSVDNLGLGLDQEPQR-IGSPTTALPA-------
--DPRNRHRDPEAIPYLEGPAYSTDE--------HKDEDPNSNTSSSQD--SNTPHDTSN
SSSVDWDTVERPG-VV-PNRNRLTMMIPRRPQ-----EGLRTDSAQKV----TRSPARG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------NSGSGGQSAGQHWVKLRSESGYFSLERQRSGQTQASS
GTPPSGPRTTT-QASS---AQRDVSQAASAQ-----------------------EAPQTS
SLPRNTQRDT----------------QRSTPRTSSPSR------VSQRDTPRIMSTQRKN
------------------------------------------------------------
------------------------------------------------------------
-------------------TPLSSPLRPTP--------------E---------------
------------------------------------------------------------
-----------------TLKTSAPEDGPH-------------------------------
-------------------------------VTSPLCAQDSSLNRTTQRDSSRTSCAQRN
NPRTSSPNRTTQRDNPRTSCAQRNNPRTSSPNRTTQQDNPRTSC----AQRNNPRTSSPS
RTTQHDNPRT--------------------------------------------------
-------------SCAQRDNPRTSSPNRTTQQDNPRMSCAQRNNPRTSSPNRTTQRDNLR
TSCAQRNNPRTSSPNRTIHQDNPRTSCVSQ-----------------------NTPRTSS
TQVDKTTASCS-------------RWEHLRSACTQRDNPR--TL---------SQGCTQK
DNPGPSSPHRATQGSSSRNPSPHRTNKDIPWASFPLRPTQSDSSRT-----SSPSRTKQN
QVPWASISLRPTQGDKP-QTSAPSKLAHNDPPQQYSPSL----ATSS-SSSHNPGHPSAS
RTSSPLHPAPRGA-------PQTSLEPSQPPCAVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDAEN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEPS-FFQDLPRASTESLVPSTDSMHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSVDSLHGSPLLLP--QVCI
GHRDAPRASSPPRHPPSDVGILAPSPPPGSS-GSRGSAPPGETRHNLEREEYTMLADLPP
PRRLAQRVPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQRPS-Q
-----GQSQL-RRQSSPAPSRQVTKPSAKQ---AEPTRQSRT--GPPHPKS-PEKHSEGD
RQLQRIAPPARTSARPPERKAQIE----------RHLESGYTGLRQPLGG----------
WQSREGLSGPQSPNRHPEKNWGSQEEGLS----LGGWPELG--GPS----------L---
--------EGIWRGPPQEHRERW------------------GQSEAWEEPPS--------
-----NGIQGG----PPRGQGSLQELPRPHQPPPSPENSWAGPAECFCARQPEAGTAMGW
RAEGTSPHQYSAERPPDLDWRDLLGLLRAPEDGAWTR---------LP--RLDWEGLLEL
L-------------QARLPQKDPTRHSRDPAKA---------PGPEPGSSDTEDTLKTE-
-SQTQPEGWA---KATLANGH--RPGQQSESPA------------QLPSPACTSTQWPT-
--TKVTSGPETSPPVALEQ-IDHLESHSP------PDLEFQPEEPEAS------------
----EPSRGEDSLADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PALF
N----------------------------------------------PY--LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSECNKENTLHGYGTQKSSLKIGEQR---TGSEVIGRG-GPRKVDGSRQS
LDYVELSPL------TPSSPQRVRTLSRST-----PERPSKQEDLERDLAQRSEERRKWF
ESTDSRT------PE-TPSGDG-----SRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGHSERRGPTSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDS-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TRQAEEREHTLRCCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-MEGLAANA-PCTHLESNGL-----------TQSHCQNCFLLEEAHG--AGHQXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGLGLGLKRG-----PSAGHPEEVP----
TAVPRRRSQELEAVPYLEGLTAFPSGSRN--------EGPNVATSSSLN--CDTPDDTSS
SSSVDWDPDERQE-EA-PTSKELPVMIPRRPQ-----EGPRADSPRRAPSVLARSAGGG-
DTTGQRKEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-------------X--X------X-XXX-XXXXXXXXXXXXXX------XXXXX------
-------------XXXXXXXXXXX-----XXXX-------XXXXXXXXXXX------XXX
XXXXXXXXXXXX---XXXXXXXX--------XXXX---------------------X---
-----------------XXX-----------XXXX-XXXXX---XXXXXXXXX------X
-------XXXXX-XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX---XXXXXXXXXXXX------X----------XXXX--XXXXXX
XXXXXXXXXXXXXXXXXX--------------------------XXXXXX---XXXXXX-
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXX-XXXXXX---------
-XX---------------------------XXXXXXXXXX--------------------
------------------XXXXXXXXXXXXXXXXXXXXXXXXXPMTAS------------
-----------------------------------------------PSRTEGGKRSCSQ
HEN-RASSSNRATQRDNSRTSCAQHDNP--------------------------------
---------------------------------------SSSPNRATQRDNPKTSCAQRD
NPRASSLNRITQQDNPRTSCAQHDNPRASSPNRATQWDNPKTSC----AQRDNPRASSPN
RATQWDNPKTSCAQRDNPRAFSPNRATQQDNPKTSCA----QWDNPRASSPNRA------
-----TQRDNPKTSCAQWDNPRASSLNRITQQDNPRTSCAQDDNPRASSPNRATQRDNPK
TSCAQRDNPRASSPNRATQRDNPRTSCAQQ-----------------------STPRTSP
IQQDKPKPSCT-------------LRDNPRTSCSQRANPHSSSLQQNTSGTSPPRSCTQK
DNPGSLSPHRSTQRSNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPTRPAQHDPPQA-SGPAQHNSPARAISSSHNPGHHSVP
RMSSPLHPTTRGA-------TQTSSEPSQPLCAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPQVSESESPHHEPPYLPPAVCIGHRDAPRASSPPRYSQFDPFPFLPDTPEAEN--PSPQ
HDPPQFPPPXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXMDSWHEPPRLP
TPGC-------IGHRDAPSFSSPPRQA-PEPSLFYQEPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLPP--QVCI
GHRDAPRASSPPRRPPSDLALLAPSPPPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
RRRLVHMEPGPQAQRSPGGRTRSPGRAEVERLFGQERXXXXXXXXXXXXXXXXXXXXXXX
-----XXXXXXX------XXXXXX----XX-----------X--AQLHLCS-TDTLHEVV
CRVP-RYSEPRRTTRTRERERRTE----------RPLESGRLGPRQPLGG----------
WPSQEEPSGSRGPHRHLARDWNSQEGAPG----PGGWRSLG--NLS----REATRAP---
--------EGTWRGPPRESEKSWGQ-----------------RAGTWEELPR--------
-----NGLPE--------GLGER-----SCPVSSPPESSWGGPAEFSQAHQPHT----PW
GAEGPCPHPCCSKRRPELDWRDLVALLQAP------RIEEPLLTSRLP--TLAWEGLLEL
L-------------QARLPRKNPAGHWGA-------------SGPEQESPGTKGAPXXXX
XXXXXXXXXXXXXXXXXXXXX---XXXXXXXXX-------------XX---XXXXXXXX-
--XXXXXXXXXXXXXXXXX-XXXXXX--X------XXXXXXXXXXXXX------------
----X-X--XXXXXXXXXXXXXXX--XXXXXX--XXXXXXXXXXX--XX-------XXXX
XXX--------X---------------------------XXXXXXX-XXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXPPCPSLTTTSPPQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYPVQRNYGFQIHTKDTIYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDRNKENTLHSYGTPKGSLKVGEQR---TGSEVIGRG-GPRKTDGQRQS
LDYVELSPL------TQGSPQRARAPARA------PDRLAKQEELERDLAQRSEERRKWF
EATDGKA------TE-TAPGEG-----PHRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLAALLNQNRGERRGPTSDS----------------------------------
----------------------------------------HEALEKEVQSLRSQLEAWRL
RGEALQDAPRPQEDGHTPPGYISQXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXXX---XXXXXIEAMK-KYQEEL-TRELSKTQSLQQGPDG-------------
-LRKQHQ-SYVEPLKRELVLXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXX------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVLLRVKENELQYLKK
EVQCLRDELQVMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MGGWKGPGQL-------RGRE
GLELKRPAAERG---------------------------GGLGAPRSPARESPAA-SRGA
-AMTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYGTPKGSLKIGEQR---TGSEVIGRG-GPRRADGPRPS
LDYVELSPL------TPSSPQRVRTLSRST-----PERPTKQEDLERDLAQRSEERRKWF
ESTDSRA------PE-TPSGDG-----PRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGHSERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNASRPQEDGHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TSNSGGRSSGRSPCELEVLLRVKENELQYLKK
EVQCLRDELQVMHKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-MEEVSGRA-PCEHFEANML-----------TQNCCQNCFHPEEAHR--ARYQELRSPSG
AEAPYCDLPQCPPVSEDPLSSSTSGCQPVVDPGLRPGPKRA---PSPSAGLPEEGP----
TATPRSRSQELEAVPYLEALTSSPRGSGN--------EDPGSDRSSSPD--SATPDDTSN
SSFVDWDTAERQE-GA-LSWDELKVMIPRQPQ-----EGPRAYSSQWAPSLLTRSPVRG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWAKLRGESGYFSLERHQPPLTQASS
MTPHSRPRSATPQASP---GQRDIAQAASTQ----HDT------------------TRAS
SPHQITQRDAPGASSTQQDTSRALSTQRNTPRASTPSR------STQQDNPRTSSNQQNN
PQLSS----------------------------------------PLRATQQDNPKTSFT
QQDNPQTSSPACTPQRENPRTPCAQRDNPRPSSPNRTTQRDNLRTPCAQRDNPRASSS--
-------------------------------------------------------NRDNP
RTP----CAQRDNPRASS------------------------------------------
------------------------------------------------------------
-------------------------------S-NRDNPR----TPC----------ARRD
NPRAASPNRATQRDSPRASSPN--------------------------------------
-------------RRDDPRASSPIRAT---------------------------------
----------------QRDNLRASSPNRTTQ------------------------RDNPR
TPCAQRDNPRASSPIRATQRDNPR-TCIQQ-----------------------NTPRS-S
TQQDKPKTSCT-------------KWDNLRPTCTRRDHTHALSFQRDNAGTSA-QYGAQK
ENLRPSSPHRSTQRNTPRNSSPHRTNKDIPWASFPLRPTQSDGSRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSFSGLTQYNLPSWATSSSHNPGHQSTS
RTSSPLYPATCGA-------PLTSSEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPSVPESESPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDMSDAEHQCQSPQ
HEPLQLPQPVCIGHRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPGDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLVQRQPGPQAQSSIGARTRSPGRAEVERLFGQERRKSEATGAFQTQDEGRSQQPS-Q
-----GHSQLLRRQSSPAPSRQVTKPPAKQ---AELAHRSRA--EPPHPRS-PEKRPEGD
RRFQGSPLPPRTSARTPERELRTQ----------RPLESGRADPRQPLGA----------
WQSQEELPGSQGPHRHLERSWSGQEGGLG----PGGWQGCG--EPS----VGVAGAS---
--------EGTWGGPPREYQ-E-----------------SWGQPGTWEEKPT--------
-----H--------ETPRELGKSS-------SPMSAPENWGGPAETSQSWQPGTPTAVGR
GVEGACPYPHGPERQPELDWRDLLGLLRAPGDGAWAH---------LP--RLDWEGLLEL
L-------------QARLPHKDTAGHRGDPTRA---------SGPEPGPAGTKDAPEQD-
SHRLCAEGQA---EATPVNGY--SAAPQPQSPA------------QPPSPACTSTHWPK-
--TKVTRGPATATLTGLEQ-TGPLGSRSPAESPSLLELQFQPEEPEES------------
----EPSGGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----TPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPARA------PDRLAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPQSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSTLRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFIASQGV-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKEA
MRNSLAE

-MEEVPGDA-LCEHFEANIL-----------TQNRCQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRG---PSPSAGLPEEGP----
TAAPRSRSRELEAVPYLEGLTTSLCGSCN--------EDPGSDPTSSPD--SATPDDTSN
SSSVDWDTVERQEEEA-PSWDELAVMIPRRPR-----EGPRADSSQRAPSLLTRSPVGG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWARLRGESGL-SLERHRSTLTQASS
MTPHSGPRSTTSQASP---AQRDTAQAAST-----REI------------------PRAS
SPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASS-----
-----------------------------------TQWNTPRASSPSRSTQLDNPRTSST
QQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSS
PNRA-TRDNPRTSCAQRDNPRASSPSRATR-DNPTTSCAQRDNPRASRTSSPNRATRDNP
RTS----CAQRDNPRASSPSRA-TRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQ
RDNPRASSPNRAAR-DNPTTSCAQRDNPRASRTSSPNRATRDNPRTS----CAQRDNPRA
SSPNRATRDNPTTSCAQRDNPRASRTSSPNRA-TRDNPR----TSC----------AQRD
NPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSC----ALRDNPRASSPS
RTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCA----RRDNPRASSRNRT------
-----IQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRAT-RDNPR
TSCAQRDNLRASSPIRATQQDNPR-TCIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPVYPAAYGA-------PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHECPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPS-Q
-----GQSQLLRRQSSPAPSRQVTMLPAKQ---AELTRRSQA--EPPHPWS-PEKRPEGD
RQLQGSPLPPRTSARTPERELRTQ----------RPLESGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG----PGGWWGCG--EPS----LGAAKAP---
--------EGAWGGTSREYK-E-----------------SWGQPEAWEEKPT--------
-----H--------ELPRELGKRS-------PLTSPPENWGGPAESSQSWHSGTPTAVGW
GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWAR---------VP--SLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------LGPELGPPGTNDVPEQE-
SHS-QPEGWA---EATPVNGH--SPALQSQSPV------------QLPSPACTSTQWPK-
--IKVTRGPATATLAGLEQ-TGPLGSRSTAKGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDG----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-MRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MEGEAGNA-SCAHCEANVL-----------AQSCCQNCFHPEEAYR--ARHQEPGSPPG
AEAPYCDLPRRPPASEDLHRASASGCQSAVGLGLGPESERR-----PVTGLPAEGP----
SATPRSRSWDSEAVPYLEGPASSLC-SFD--------EGPDSGTSSSPD--CDAPDDTSN
SSSVDWDVVKRQE-EA-PGGDEITEMIPRKLQ-----EGSRADSTHRAPSVLTRSPVGGD
T-ASQRKEVD------GVIARGHLGPWARLTLLAQVLIIVTVSSNDGAGVLSMQPALHTS
PTGPESHVTPAPTAWALPS----L-LHC---VAPDLHFQHRQG----SGIWARASRSYPG
GQAWLPMAPSTLECAARAQLLRPPWGRTRLARCNCPRERWRNLIRAVAVAEEGTEKENTR
SQLLVWVSVWTA----------------------M--PFTDRGELGRRCKQCGPGWI---
--QSPGRG---VDSGKRCRAGCSV--MGKPEQRAAAAFGRI---KTGNCESNWPGGQGGP
RATSHFAKHALPSPCI--ASSLLDPGGGSRSAGQHWAKLRGESGHF-LERHR-----ASS
ATPQSGPRSTTPQASS---LHRSA------Q----RDAAQ--------TASIQLDAPRAS
SPSQTAQRDNPRTSSTQQDTHRASSTQQSTPRTASPSR------ITQRDNSRTSSTQRSN
----------------------------------------PRVSSSPRAAQQDNSRTSST
QQDNPQTSFSACTSQQENSRTSCAQRDNPRAS-PNRTT----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------QRENSRSSCAQRD
NPRGSSPNRTTQRENSRTSCAQRDNPRGSSPNRTTQRENSRTSC----AQKDNPRGSSPN
RTTQRENSRTSC------------------------------------------------
---------------AQRDNPRGPSPNRTTQRENSRTSCAQRDNPRGPSPNRTTQRENSR
SSCVQRDNPRASSLNRTTQRENSRTSCTQQ-----------------------NTPRTSS
---------------------------------TQRNNPQSSSFRRDHPGSSSPQCCTPK
NNPRPSSPHRSTQRNNPRNPSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQADRP-QTSSPTKPAQRDSPQSSSGPPQHSSPARASSSSHNPGPHGAP
RTSTPLYL-TRGA-------SQTSFESSQPPCAVCIGHRDAPRASSPPRYLQYDPFPFFP
DPHASESESTHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEN--QSPQ
HDPPQFPPPVCIGYRDAPRASSPPRQA-PEPSLLFQDFPRASTESLVPSTDSLHEPPHIP
TPVC-------IGHRDAPYFTSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPMLPP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQREPGPQ--GSNGGRTRSPGRAEVERLFGQERRKSEAPGTFQARDEGRSQRPS-Q
-----GQSQLLRRQSSPALSREVTTPLAKQ---AEPARRSRA--EAPPP-----RRPGGD
LRLQGSSPPPRTSARTSERERRTE----------KPPERGREGPRQPPGG----------
WQSQEELPGAPGPHRHLERGWSSQEEGPG----LGGWQGLG--EPS----GGATRAL---
--------EGTWRGPLRESEESW------------------GQSEAWEKPPS--------
-----NGVQK-------------PELFGPPQPMSLPENTREGPAEFSNSWRPETDTAMGR
GTEGACPHLHGPERRLELDWRDLLSLLGMPREGAWARPEEPTLASRLP--RLDWEGLLEL
L-------------QAQLPRKDPAGHWGGPLTA---------PGPELGSPGTKHALERE-
R-QSQPAGWA---EATLVNGH--SPEQGPQSLA------------QLPSPACTSTQWPK-
--TKVTSGPETSTTAGLE--TSQLGSRSPAEGPSSADWEVTPEASVEE------------
----EPR--GDSLTGQKRADSANKH-LEGEAGERGSGCVCVCFQLPSSP-------PTPL
SHA------------------------------------------------TRSL-HATR
HLGLPDLLNFKKGWMSILDEPGEPL--LPHPADDAQSTSEWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPISAPDVTKLSDCNKENTLHSYSTQKGSLKVGEQR---AGSEVISRG-SPRKADGQRPS
LDYVELSPL------SQGSPQRARTPART------LDRPAKQEELERDLAHRSEERRKWF
EAVDSRA------TE-TPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVLSLRAQLEAWRL
QGEAPQGAPRSQEDGHIPPGYISQEAWERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELNKTRSLQQGPDG-------------
-LRKQHQ-SDMEALKRELQVLSEQYSQKCLEIGTL-TQQAEEREHTLRCCQQEGQELLRH
NQELHARLSEEIDRLRGFIASQGT-----GSGCGRN-ERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
MRNSVAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--FQPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVFTLSAMTSGIRRNWIEALRKNV
RPVSAPDVTKLPDCDKEN-FHNCVPQKGSLRTEEQQRPGSGSEGNSKG-SHWKADGQRHA
FDYVELSPLPQDP-GNQG----TKGSVKI-----SDRTPRY-EELERDLAIRSEERRKWF
ETPDGRVPNSDGPAGDPSRKAG-----EQDLPTPPLSEDQRIRLNEEIEKKWLELEHLPL
KDLRRVPLTTLLNQ----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------

-MEEVSGRA-PCEHFEANML-----------TQNHCQNCFHPEEAHR--ARYQELRSPSA
AEVPYCDLPRCPPVPEDPLSSSTSSCQPVVDPGLRPGPKRA---PSPSAGLLEEGP----
TATPRSRTQELEAAPYLQGLTSPLQGSSN--------ENPSCDPSSSPD--SATPDDTSS
SSFVVSDK---------ERW----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------NMR
-------AVWTPRLTLSLSLLSPDTGGGGRSAGQHWAKLRGESGYFSLGQHRSPLTQASS
MTPHSGPRSTTPQTSP---GQRDVAQAVSTQ----PDT------------------ARAS
SPHQITQRDGPGASSTQQDTSRASSTRRNTPRASAPSR------STQQDNPRTSSNQQNN
PQLSS----------------------------------------PLRATQQDNPKTSFT
QQDNPQTSFPACTPQQENPRTPCAQQDNPRPSSPNRTTQRENRRTACAQRDNPRASSP--
-----IRDNPRTPCAQASSPI---------RDNPRTPCAQRDNPRAS-------------
---SPNRATQRDNPRASSPIRD--------------------------------------
------------------------------------------------------------
------------------------------------SP----RTQY----------AQRD
DLRASSPNRTTQRDNLRTPCAQRDNPRASSPNRTTQRDNPRTPC----AHRDNPRASSPI
RATQRDNLRTPCAQRDDLRASSPNRTTQRDNPRTPCA----QRDNPRVSSSIRA------
---------------TQRDDLRTSSPNRTTQ------------------------RDNPR
TPCAQRDNPRASSPIRATQRDNPR-TCIQQ-----------------------NTPRSSS
TQQDNPKTSST-------------KWDSLRLTCTRRDHTHSLSFQPDNPGSS-SQYCTQK
ENLRPSSPHCSTQRNTPRNSSPHRINKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSSGPTQYNLPSRATSSSHNPGHQSTS
QTSSPLYPATCGA-------PLTSSEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPSVPESESPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDMSDAEHQCQSPQ
HEPLQLPQPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSVDSLHEPPHIP
APVC-------IGHRDAPAFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLVFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLANLPP
PRRLAQRQPGPQAQSSIGGRKRSPGRAEVERLFGQERRKSEAAGAFQTRDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKPPAKQ---AEPAQQSRA--EPPRPRS-PEKRPDGD
RWFQGSPPSPRTSARTPERELRTQ----------RPLESGRADTRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSGQEGGLG----PGGWRRCG--EPS----LGAARAS---
--------EGTWGGPPREYQ-E-----------------SWGQSETWEEKST--------
-----H--------EAPRERGKSS-------SPVSTPESWGGPAETSQSWQPGSPTAVGR
GAEGACPYPHGPERQPELDWRDLLGLLRAPGDGAWAR---------LP--RLDWEGLLEL
L-------------QARLPHKDPAGHRGDPARA---------SGPEPGPPGTKDAPEQD-
PHS-QPEGQA---EATPVDGY--SAALRPQGPA------------QPPSPTCTSTQWPK-
--TKVTRGPATATLTSLEQ-MGPLGSRSPAESPSLPELQFPPEEPEKS------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGQQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTSARA------PDRLAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPQSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSIPRSQEDGPIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVDALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHARLSEEIDRLRSFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELRLMQEDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

--------------------------------------------------CSQEPGRPSS
AEVPYCDLPRRRPAPEDPLSTPTSSCQSVVGPGRGPEPERG-----PPAGLLAEGF----
TAAS--RSREPEAAPYFEGLASSPCGSFN--------ESPDSGTS-------EAPDDTSD
SSLVDWDTVERRE-EA-PSGDNFTVMIPRKSQ-----EVPRADGARKAPPLLTQAPVGGG
DTAGRKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------GSGGGNRSAGQHWAKLRA----FPWARPRPAPPPASP
ATPQSGPRSATSQASS---LHRSAPRNTVQAVSPQRGASRASSPLRIIQRDKQRDTPRAT
SPSRVAPRDNLRTSSSQQDTPKTSSTQRDTPRATSPSR----------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------VAPRDNLRTSSSQQDTPKT--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------SSTQRD
TPRATSPSRVAPRDDLRTLST---------------------------------------
---QQDTPKTSSTQRDTPRATSPSRAAPRDKLRTSS------------------------
-----TQQDTPKTSSTQRNTPRATSPSRVVPQVSPRTSSTQRNNPWVSSPPRATQQDTSR
ASYTQQDNPQTPVPTCTPQRGNPRPSCAPQ-----------------------NTPRSSS
AQRDNPKTSCT-------------QR----------DNPKSSSSRRENPGSTSCQGCTQQ
DNPRASSPDRSSQRNNPRNASPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPARPAQRDSPQSSSAQL----TIPATATSHNPGHHGAS
RTSSPLHPTPRGA-------PQTSSELPQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
DPHTSESESPHHDPPYMPPAVCIGHRDAPRASPPPRHTQFDPFPFLPDTSDAEN--QSLQ
HDPPQFPPPVCIGYRDAPRASSPPRQA-PEPSLLFLDLPRASTESLVPSMDSLREPPAIP
TPVC-------IGHRDAPSFSSPPRQP-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSSDSLRGSPMLPP--QVCI
GHRDAPRASSPPRHPPSDLALLAPSPPPGSSGGSWGSAPPGEIRHNLEREEYSVLADLPP
PRRLAQREPGPQ--GSNGGPTLSPG-AEVERLFGQERRKSEAPGAFQARDEGRSQWPS-Q
-----GQSQLLRRQSSPALGREASTKLGSFQ--TDPTQPGAW--SPTHPLTSSSGNQPPS
EWLQGSSPPPRTSARTPEREQRTQ----------RPLECGRVGPRQPLGG----------
WRSQEEPPGSRGPHGCLERGWRSREEGPG----LRGWQGLG--ESS----RGPARVP---
--------EGVWRGPPRESE-SWSRGGPP-------------------------------
-----------PAGPAGRGGGSLQELSSPRQPVSPPENSRAGPGEFSKSQRPETLPAVGR
GAEEACPHLCGPKRQAEFDWRDLVSLLGVPREGMWSRPEEPTLTSHLP--RLDWEGLLEL
L-------------QAQLLHKDPAGHWVGPGQA---------------SPGTKDTLELEQ
DRHSQPEGGA---GAALVNGY--DPGQWPQSSA------------QPSSPTSISTQWPK-
--TKVTSGPESSATTGLEE-TGQLGSRSPAEGPSSPRREFQSKEPEES------------
----ERSRGQDSLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHSYGTPKGSLKAGEQR---VGSEVISRG-GPRKADGQRQS
LDYVELSPL------TQGSPQRARTLARA------LDRPAKQEELERDLAQRSEERRKWF
EATDSRAAEKHRAPE-PRAGEG-----PRRVLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGRGERRGAPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGEAPQGAPKSQEDGHIPPGYISQEACERSLAEMESSHQQVMQELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELNKTRTLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHTRLSEEIDRLRSFIASPGLLAGAWGLGLGRSQDHPRLWLCVLLRVKENELLYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------NNPRHSSPHRTNKDIPWASFPLRPTQSEGTRT-----SSPSRSKQS
EVPWASIALRPTHGDRP-QTSSSTRPALHDPPQ-SSGPTRQNSLSRATFSSHNPGQQSAS
QTSSPLHPTARAA-------LQT---SPSLCCAVCIGHRDAPQASSPPRYLQHDPFPFFP
DPRTPESELPHHEPPYIPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDSSE-NQSPQ
HEPPQFPPPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEPPHIP
TPVC-------IGHRDAPSFSSPPRQP-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSLPRHPPSDLGLLAPSPPPGSLGGSRGSLPPGDTRHNLEREEYAVLADLPP
PRRLAQREPGPQAQCSNGGRTRSPGRAEVERLFGQERRKSEAPGTFQARDEGLLQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKPPAKQ---AEPARQSRA--EPPHSRS-PERQPEGD
RRLQWSSLSPRTPSRTPERELRTE----------RPPESGRAVRRQPLGE----------
WQSQEEPPGSQCPHRPQERSWSSQEEGPD----PGGWRRYG--EPS----LGAARAP---
--------EEAWQGPPREYR-E-----------------HWGQSEAWEEPPR--------
-----K--------PAQRASGSLQ--ESPHQPMGPAESSWAGPAEFSKPWQPETP-----
---------TGPERHPELDWTDLLGLLRAPGEGTWAR---------LP--RLDWQGLLEL
L-------------QARLPRKDPAGHWGDPAKA---------LQPEPGPPDTKEALEQE-
QHS-QPEDWA---KATPVNGH--GPGQWPQSPA------------ELPSPAHTSTQWPK-
--TKVTSEPETSTMAGLEQ-MDQPASR----SPSLPELEFQTEEPEKS------------
----EPSRGPDSLTDQTQAD----------------------------------------
------------------------------------------------------------
---SPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPASAPDVTKLSDCNKENTLHSYSTQKGSLKPGEQR---TCSEVIGRG-GLRKADGQRQS
LDYVELSPL------TQGSPQRARTPARA------PDRPAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPSSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQSAPRTQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-TRELNKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIERLRSFIASQGT-----GNGCGRSNERSSCELELLIR-----------
------------------------------------------------------------
-------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------MGNSW-NNEEKLFHQHELDGGQPPKSTCSPRSH
DPY---------------------------------------------------L-DTSK
-KHKPDLLNFKKGWMSILDEPGE-----------------WTKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEYAVQRNYGFQIHTKDGVFTLSAMTSGIRRNWIEALRKSI
RPTSVPDVTKLSDCNKENSFRGYGSPKSSIRPEEQR-PSAGPEAISRG-SHRKADGQHHA
FDYVELSPLQQGSQLSHGSPQRTRGSARA-----TEAAAGKREDLERDLALRWEERRKWF
ESPASGVLQ-------TDGPAGDLCQKGQEPPGPHLSETQKSRLSEEIEKKWQELERLPL
KDSKRIPLMALLNQGKGNQGEKNEA-----------------------------------
-------------------------------------------LEKEVQVL-----RSQL
ESFRAHNVAKSHKDGQVPRGYISQEACERSLAEMETSHQQVMTEMQRHHQREVERLQLEK
-ERLLSEEAS---ATAAAIEALKKAHRDEL-NKELSRTRNFQKSGSN-----------AD
ILQQQHQ-SDVESMKRELQVLSEQYSQKCLEIGDL-VHKAEEQEHMLQRCQQEGKELLRQ
NQELQRRLSEEIGQLRAFITAQVS-----GDGSSHNSERNSCELEVLLRVKENELQYLKQ
EVQCLREEIQMMQKDKRFASGKYQDVYAELNHIKRRSEREIEQLKEHLRLAMAALQEKEM
MHNSIG-

-MEEVPGDA-PCEHFEANML-----------TQNRRQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSSCRSVVDPGLGPGSRRG---PSPSAGLPEEGP----
TAAPRSGSHDLEAVPYLEGLTTSLRGSCN--------EDPGSDPGSSAD--SATPDDTSN
SSSVDWDTVERQE-EA-PNWDELAVMIPRRPQ-----EGPKADSSQKAPSLLTRSPVGG-
DTAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWAKLRGESGFFSLERHRSTLTQAAS
MTPHSGPRSTMPRASP---AQRDTAQAAST-----RET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASFTQRNTPRASSP------SRSTQQDNPRTSS-----
-----------------------------------NQQNNPQYPSPQRATQQNNPRTSST
QQDNPQTSFPTCTPQWDNPRTPCARWGDPRASSPNRATQRDNPRTSCAQRDDPRA---FS
PNTA-TRDNPRISCAQQDNPRTSSPNRTTQQDNPRTSCAQRDNPRAFSQI--KATQQDNP
RMS----CAQRDNPRASSPNRT--------------------------T-RDNPRTSCAQ
RDNPRASSPNRTTR-DNPRTSCAQWDNPRTSSPN--RTTQRDNPRTS----CAQRDNPRQ
DNPRA--------------------SSPVRAS-QQDNPR----TSC----------AQRD
NPRASSPNRTTQQDNPRTSCAQRDNPRASSPVRASQQDNPRTSC----AQRDNPRASSPN
RTTQQDNPRTSCAQRDNPRASSPVRASQQDNPRTSCA----QRDNPRTSSPNRT------
-----TQRDNPRTSCAQRDNPRTSSPNRT-T------------------------RDNPR
TSCAQRDNPRASSPNRASQQDNPR-TSIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRDNLRPTRTQRDRTQSFSFQRDNPGTSSSQCCTQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRVTSSSPNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPYAPESELPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHEGPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDAPGTS------------------
-----------------------------------MESLAPSTDSLHGSLVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSRGSRGSAPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQAQHSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAEQ---AELTWRSQA--EPPHSRS-PEKRPEGD
RWLQGSPPPPRTSARTPERELQTQ----------RPLESGQAGPRQPLGA----------
WQSQEEPPGSQGPHRHLARSWSSQEGGLG-----------------------AAKAL---
--------EGAWGDPPGEYR-E-----------------SWGQPEAWEEAAT--------
-----H--------EPPRELGKRS-------PLTSPPENWGGPTESSQSRRPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWAR---------LP--RLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPAPRPQSPA------------QPPSPACTSTQWPK-
--TKVTRGPATGTLAGLEQ-PGPLGSRSTAEGPSLPELQFQPEEPEES------------
----EPNRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHNYGTQKGPLKAGEQR---AGVEVISRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MEEVPGGA-PCEHFEANML-----------TQNRCQNCFHPEEAHR--ATYQELRNPSG
AEVPYCDLPRCPPVPEDPLSSSTSDCQPVVDPGLRPGPKRA---PSPSAGLPEEGP----
TATPRSRSQELKAVPYLEGLTSSLRGSGN--------EDPGSDPSSSPD--SATPDETSN
SSFVDWDTAERQE-EA-LSWDKLKVMSRRQPQ-----EGPRAYSSQQVPSLLTRSPVRG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWAKLRGESGYFSLERHWSPLTQASS
MTPHSGPRSATSQTSP---GQRDIAQAACTQ----RDT------------------ARAS
SPHQITQRDAPGASSTQQDTSRTSS-------------------TTQQDNPRTSSNQQNN
PQLSS----------------------------------------PLRATQQDNPKTSFT
QEDNLQTSFPACNPQQENPRTPCAQRDYPRPSSPNRTTQRENRRMTCVQWDDHRASSP--
-----NRANPRTPCAQRDNPRVSSPNR----ANPRTPCAQWDNPRASSPNR--ATQRDNP
RASSPNRATQRDNPRASSPNRA-T-----------------------------------Q
RDNPRASSPNRAT----------QRDNPRTSSPN--RATQRDNPRTSSPNRATQRDNPRT
SSPNRATQ---------RDNPR---TSSPNRATRRDNPRTSSPNRA----------TQRD
NPRTSSPNRATQRDNPRTSCAQRDNPRTSSPNR---------------------------
-----VNPRTSCAQRDNPRASSPNRATQRDNPRASSPNRATQRDNPRASSPNRA------
---------------TQRDNPRTSSPNRTTQRDNPRTPCAQRDNPRASSPNR--------
--ATQRDNPRASSPNRATQRDNPR-TCIQQ-----------------------NTPRSSS
TQQDNPKTSCT-------------KCDNLRPICTQRDHTHSLSFQRDNPGTSS-QYCTQK
ENLRPSSPHRSTQRNNPGNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQLDPPQSSSGPTQYNLPSRATSSSHNPGHQSTS
WTSSPLYPATCGA-------PLTASEPSQPPCAVCIGHRDAPRASSPPRFLQHDPFPFFP
EPSIPESESPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDMSDAEHQCQSPQ
HEPLQLPQPVCIGYRDAPRASSPPRQA-PEPSILFQDLPRASTESLVPSMDSLHEAPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
RRRLAQRQPGPQAQSSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQTRDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKPPAKQ---AEPAERSRA--EPPHPRS-HEKRPEGD
RRFQGSPPPPRTSARTSEKELLTQ----------RPLESGRADPRQPLGA----------
WQSQEEPPASQGPHRHLERSWSSQEGGLG----PGGWWGCG--EPN----LGVARAS---
--------EGTWGGPPREYR-E-----------------SWGQPETREEKPT--------
-----H--------EVPRELGKSS-------PM-STPENWGGPAETSQSWQPGTPTAVGQ
GAEGACPYPPGPERQPELDWRDLLGLIRAPGDGVWAR---------LP--RLDWEGLLEL
L-------------QARLPHKDPAGHRGDPARA---------SGPEPGPPGSKDAPEQD-
SHS-QLEGQA---EATPVNGY--SAAPRPQSPT------------QPPSPACTSTQWPK-
--TKVTRGPATATLTGLEQ-LGPLGSRSPAESPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGEPP----SPSLTAASTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQAPPQRARTPARA------PDRLAKQEELERDLAQRSEERRKWF
EATDSRA------PE-VPAGEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RDNKRVPLTALLNQSRGERRGPQSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQESQELLRH
NQELHAHLSEEIDRLRSFIASQGM-----GNGCGRSNERSSCELEMLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKEA
MRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--PQPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDSN
AEEADELDGEIDLRSCTDVTEFAVQRNYGFQIHTKGAVFTLSAMTSGIRRNWIEALRKTV
RPANAPDVTKLSDCNKENTVGGYGSQKGPLRAEELR---SGPGAEVIGRGSRKVDGQRQS
FDYVELSPL------NQGSPQRTRRGSRA------PERGAKQEELERDLAQRSEERRKWF
EATDGGT---------------------------GLTEDQQSRLNDEIEKKWLELEQLPL
RQSKRVPLTALPNQGKGARRSSPAGG----------------------------------
---------------------------------------TNEALAKEVQSLKAQLESLRL
HGEGHRDPPKTPGDNSVPRGYISQVKCIRSLRLGAGRGRSQ-NPF--HYQFSLPL-----
---TVC----------------------ELPSHS-------LVGPTGVRGAPAMAGRGRD
HGWGSAR-TDVDSLKRELQVLSEQYSQKCLEIGDL-TRQAEEREHVLNCCQREGKELLRQ
NQ----------------------------------------------------------
------------------------------------------------------------
-------

----------MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQ--ACSQEPHSPSS
AEAPYFDLPRCPPALQDPLRTTTCVGQSVHSLGLGLGQEPQR-VWSPTTALPAEGP----
AAAPKNRHQDSEGIPYLEGLACSSCTDDNDNKDE--DKDPNSNTSSSQD--SNTPHDTSN
SSSVDWDTAERPG-VV-PNRNRLTEMIPRRPQ-----EGLRADSVRKA----TRSPARG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------NSGSGGQSAGQHWAKLRSESGYFSLERQGSGQTQASS
GTPPSGPRTTT-QASS---AQRDVLQAASAQ-----------------------GAPQTS
SLPRNTQRDTQQST----------PRTSSPSRVSQRDT------PRVMSTQRKN------
------------------------------------------------------------
------------------------------------------------------------
-------------------TPLSSPLRATP--------------E---------------
------------------------------------------------------------
-----------------TLKTSAPEGGTR-------------------------------
-------------------------------VTPPPCAQDSSPNRTSQRDSSRTPCAQRN
NPRASSPNRTTQRDNPRTPCAQRDN-----------------------------------
------------------------------------------------------------
-----------------------------------------RDNPRASSPNRTTQRDNPR
TPCAQRDNPRT--------------SCTSQ-----------------------NTPRTPS
TQADKTTASCS-------------KWEHLRSACTQRDNP--RTF---------SQGCTPK
DNPGPPSPRRATQGSSSRNPSPHRTNKDIPWASFPLRPTQSDNPRT-----SSPSRTKQN
QVPWASISLRPTQGDKP-QTSASTRLAHNDPPQQYSPSL----ATSS-SSSHNPGHPSAS
RTSSPLHAAPRGA-------PQTSLESSQPPCTVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEPS-FFQDLPRASTESLVPSTDSMHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSIDSLHGCSLLPP--QVCI
GHRDAPRASSPPRHPPSDVGLLAPSPPPGSS-GSRGSAPPGETRHNLEREEYTMLADLPP
PRRLAQRGPEPQAQGSHEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQRPS-Q
-----GQSQL-RRQSSPAPSRQVTKPSAKQ---AEPTRQSRT--GPPHPKS-PDKRPEGD
RQLQRTSPPARTPARPPERKAPIE----------RHLERGYTGPRQPLGG----------
WQSQERLSGPQSPNRHPEKSWGSQEEGPS----LGGWPELE--GPS----------L---
--------EGIWRGPPQEHRERW------------------GHSEAWEESPG--------
-----NGIQGG----PPRGQGRLQELSRPHQPTPSPENFWAGPAECLCALQPEASTAMGW
RAEGPSPHQRSAERPPDLDWRDLLGLLRAPEDGAWTR---------LP--RLDWEGLLEL
L-------------QARLPPKDPARHWHDPAKA---------SGPELGSSSTEDILKTE-
-PQTQPEGRA---EATLANGH--RPGQQSESPA------------QLPSPACASTQWPT-
--TKVTSGPETSPLAALEQ-IDHLESHSP------SDLEFQPEEPETS------------
----KPSQGEDSRADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PALF
NPY------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSECNKENTLHGYGTQKSSLKIGEQR---TGSEVISRG-GPRKADGPRPS
LDYVELSPL------TPSSPQRMRTLSRST-----PERPTKQEDLERDLAQRSEERRKWF
ESTESRT------PE-TPSGDG-----SRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGHNERRGPTSDS----------------------------------
----------------------------------------QEALEKEVQSLRAQLEAWRL
RGEAPQNTPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPES-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQGT----TGNSCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ERG---------GGL-------AAPR
SPA------------------------------------------------RELLAAPRG
AAMTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPASAPDVTKLSDCNKENTLHGYGTQKGSLKVGEQR---TGSEVISRG-GPRKADGPRPS
LDYVELSPV------TQGSLQRARTLPRA------AERPAKQEELERDLAQRSEERRKWF
EATDSRA------PE-TPGSEG-----PRRGLGAPLTEDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSHGGRRG---ES----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
QGKAPQNAPRAQEDGHTPPGYISQEACERSLAEMESSHQQVVEQLQRHHERELRRLQQEK
-ERLLAEETA---ATAAAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-LDVEALKRELQVLSEQYSQKCLEIGSL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRGFIASQGN-----GSSCGRSNERSSWELEVLLRVKENELQHLRQ
EAQCLRDELQLMQKDKRFTSGKYQDMYVELNHIKTRSEREIEQLREHLRLAMAALQEKEA
ARNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------LAS-SSRAGETRGHLSAGGTEGKRVLERQEYTVLADLPK
PKRLGRGDAA--D--RCGSRTLSPGRVEVERIFGCERRKSETLEAFQALEEGRVERLDGK
TPVPPSKGRVIRRQSSPSLPREGQRL------SWHPESRSRDSKEPRHS-PSPARQTERA
GVALRPMC----PSPRVERDWRK---PQEPTSPTQRLERGGSSPRSPSPR-----SPSPT
SRLERRPGGTQSPSQHTEKDWRNRAERNQ-----VSWQAGSMGKATERKSWGNTLHPPSL
VKRIDGSKPGLARGAERQRG-------DTS---------GKQLECSWRSLR---------
--D-K-LQPPHAGKGTDNEWKGRGKPLHPMSPMRPPEQDWKGRGDARQAQKAEK----DW
RGQEKSLCHMDLMQQLERDWRSPARGKGD-----WQNLP--GTADTAPTQP---------
----QH------------------------------------------------------
-----------------------CGPAWRNQH----RPSQVSLGPCIPVAARTGSQLPA-
--PAITPA----------------------------------------------------
----------------------------------------QCWIPPV---------PPLA
---SSHLRCLEPAP-----DLRMALLSCPLPPPALA---------FSSDG-GFSSNLVLF
SAHIPDLLNFKKGWMSILDKPGE-----------------WKKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAIFTLSAMTSGIRRNWIEALRKNV
RPISAPDVTKLSDCNKENTIRNCIPPKSSLRVDEQQQ--PSSEGSTKG-STWKADGPRHA
FDYVELSPLQQDP-QNQGSPPRTRGSLRV-----SERVSKH-EDLERDLAVRSEERRKWF
ESPDGRVSNSDGPGGGA------------RLACCPLSEEQRARLNEEIEKKWLELERLPL
KDSRRVPLTTLLNQGKGNHGDA-NEALKKE------------------------------
-----------------------------------------------VQSLRAQLESCRA
RNESLREAAKSQGDGHMPRGYISQEACERSLAEMESSHQQVMEELQRHHQREMERLRQEK
-ERLLAEEAA---ATAAAIEALKKAHREEM-NKELGRTRSFQQCGSV-----------TD
ALQKQHQ-LDVDSLKRELQVLSEQYSQKCLEIGQL-TEKAEEREQTLQHCQQEGKQLLRK
NQELQIRLSDEIGKLRSFITSRCS-----GDRSPQNNERSSCELE---------------
------------------------------------------------------------
-------

MMEKVTGNVPPCGHFEADVF-----------ARSYCQNCSEVQEAHCEPSTQQEIGGPLG
AEASYCDLQQASPYPNDTLCILVPSCELVVAAGRGQRS--------ESLGVPVEWPLAES
LAAQPWGQEIRSGVPYLESLTCTHFRSCS---EDSG-AFAIIRPDCNPG--RHYPDDTST
PDSVDLDAVDWPD--KPLGFDELPMMFSRHQE----RERPQADGPRRAPS----SV----
--SRSSAT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DPSPGNQSSRESRAKSRGESSYFCLERNKLDPTQTSQ
S-QQSGLRSTTRNPGPTK--P-----------THH-DTYSASSS----HRSIQRDTTRAS
SPHRST------------------------------------------------------
------------------------------------------------------------
------------------------QRDTTRASSPHRSTQRDTTRASSPHRSTQ-------
--RDTTR---------ASSPHRSTQRD-TT------------------------------
--------------------------------------------------RASSPHRSTQ
RDTTRASSPHRST----------------------------------------QRDTTRA
--------------------------SSPHRSTQRDTTRASSPHRSTQRDTIQCSATQWD
N--------------PRTCSTQRDNPGTSSPARPTTK-DNP---RASSTQRDNPRTCS--
--T------------------------QRDNPGTSSPARPTTKDNPRASS----------
-----TQRDHPRTCSTQRDN----------------------------------------
--------PGT--SARPTPKDNPRASS---------------------------------
TQRDNP-----------------------RTCSTQRDNPGTSSPARPTAKDNPRASSTQR
DSPGPSSPTRSSQRSNPRTSSPHRTNRDIPWASFPLRPVQSDGPRA-----SSPTRSKQS
EVPWASFPLRPVQGDNS-RTSSPTRSSQ-ISSK----TSQRDIPTRGSICHSGPRSSTPP
LSSTRTSQASSLS-------RSTSLDSPQPSSAVCIGHRDAPRASSPPRFCQHDPFSFFP
DPHDDESQSPHHDPPYIPPAVCIGHRDAPRASSPPRHSQYDPFPFLPNTSDTES--QSPQ
HDPPQMPPPVCIGHRDAPRASSPPRQSPQESSLLYQDAPGASSESLAPSTSSMHDPPHIP
PPVC-------IGHRDAPPFSSPPRHVHHDPSLLYQDPPGASCESLALSMDSQHDPPQIP
TPVCIGHRDAPLFTSPPRQAYHDPSLLNQDPPGASSESLAPSMDCFHGHDALQPTLHVCI
GHRDAPRASSPPRHWDPPGVARCSIPPPGPSGCKG--SGTGDGRHNLEREEYTMLADLPQ
PKRLNQKEAMGKQSGNASDRSRSPGRSEVDRIFGNERRKSEALETYQALEVGRAQRGG-L
-----ASGQLQRRQSSPALCREVTKKSPQS---SEQARRGRM--EPPYTKS-PERRLEGD
RRNKGGSTPPKNLVKLPERESRARGQLVHSKSLDIPPENDRLGHRQPSGLRHLGKSMEEE
WMPPEESAIPRSPQRHLERDRGGPGQAYSEGCLEGDFQSQGGYSCN----KALEMYP---
--------DSEWRGPAKEIVGCWRSLAEQVCCRRLERLQQSGQLVDWDELPQPKGSEWDC
NGLGGLTQPTGPERPTKVSWGNLGELAHPRRLERADEMDWGSL-----------------
---GELPLPRRPERPLAMDWRELGGLPHPRGPE---RPV-----------GSDWGSLGEL
L-------------RPRSPELCREMVWGAKGEPVFTEGSWLENGEARPPKGPEEAPEREW
QSTSEPAGLVIHDRQAEMNGY--SPEERLLSPIPSVEENGA-DLVQP----IGSAPWPK-
--IKMESRQRALEVAGLQEEEDKMGNNLQLGP----HPSKE---PEPEGSALPEPGHPGA
AEGQ----EPSLMTDQENTDTADNVLTKGKAVRPTKGRLVTSWRMPGDQ-------PTLF
NPFLI------------------------------------------------SL-GVLK
-WRRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDSN
AEEADELDGEIDLRSCTDVTEFPVQRNYGFQIHTKEAIFTLSAMTSGIRRNWIEALRKTV
RPASAPDVTKLSDSNKENTIHGYSSQKGSSRAEEQR-PAP--EVIGRS-TGRKADGPRQS
FDYVELSPLHQGA------PQRRGGSVR----------GAKQEELERDLAQRSEERRKWF
EASDSRAGE-------PAASEG-----PRKALGGPLTEDQQSRLSDEIEKKWLELERLPL
RESKRVPLTALLPQSKGEHKGPPGDS----------------------------------
----------------------------------------TEALEKEVQSLRAQLESCRL
RGDGSRDPPKPHEDGHIPRGFISQEACERSLAEMESSHQQVMEELQRHHQRELERLQQEK
-EWLLAEETA---ATASAIEAMKKAFKEEL-NKELGKTRSLQQG--------------PE
SLRKQHQ-SDVDSLKRELQVLSEQYSQKCLEIGDL-TRQAEERERILQHCQQEGKGLLRQ
NQELHSRLSEEIGQLRNFIASQAS-----SEGHGRNNERNSYELKMLLRVKENELQYLKK
EVQCLRDELQMIYKDKRFASGKYQDVYVELNHIKTRSEWEIEQLKEHLRLAMAALREKES
LRNNLDN

-MEEVPGDA-LCEHFEANIL-----------TQNRCQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRG---PSPSAGLPEEGP----
TAAPRSRSRELEAVPYLEGLTTSLCGSCN--------EDPGSDPTSSPD--SATPDDTSN
SSSVDWDAVERQE-EA-PSWDELAVMIPRRPR-----EGPRADSSQRAPSLLTRSPVGG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWARLRGESGL-SVERNRSTLTQASS
MTPHSGPRSTTSQASP---AQRDTAQAAST-----REI------------------PRAS
SPHRITQRDTSRAS------------------------------STQEDTPRASS-----
-----------------------------------TQWNTPGASSPSRSTQLDNPRTSST
QQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSS
PNRA-TRDNPRTSCAQRDNPRASSPNRATR-DNPTTSCAQRDNP----------------
--------------------------------------RASRTSSXXXXXXXMGFH----
-------------------------------------RVSRAG-----------I-----
-----------------------------------------------------------D
LL-------------------------------TF--AS---------------------
-------ETIRCTNHQTVLLNADPEAPHEITPRTSCA----QQDNPRASSPNRT------
-----TQRD------------TASSPNRTIQQETLRTSCTRQDNPRTSSPNRAT-RDNPR
TSCAQRDNLRASSPIRATQQDNPR-TCIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRDNLRPTCTQWDRTQSFSFQRDNPGTSSSQCCTPK
EKLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSHSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPVYPAAYGA-------PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-LEPSLLFQDLPRASTESL--------------
--------------------------A-PEPSLFFQDPPGTS------------------
-----------------------------------ME-------------MLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLERDEYTVLADLPP
PRRLAQRQPGPQAQCSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPS-Q
-----GQSQLLGRQSSPAPSRQVTKLPAKQ---AELTRRSQA--EPPHPWS-PEKRPEGD
RQLQGSPLPPRTSAGTPERELRTQ----------RPLESGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG----PGGWRGCG--EPS----LGAAKAP---
--------EGAWGGTPREYR-E-----------------SWGQPEAWEEKPT--------
-----H--------ELPRELGKRS-------PLTSPPENWGGPTESSQSWHSGTPTAVGW
GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWAR---------LP--SLDWEGLLEL
L-------------QARLPRKDPAGHRDDPARA---------LGPELGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPALQSQSPV------------QLPSPACTSTQWPK-
--IKVTRGAATTTLAGLEQ-TGPLGSRSAAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTASTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHNYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKHEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDG----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-MRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRSFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDIYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

-MEEVPGGA-PCEHFEANML-----------TQNHRQNCFHPEEAHG--ARYQELRSPSG
TEVPYCDLPRCPRAPEDPLSASTSSCRSVVDPGLGPGPRRG---PSPSAGLSEEGP----
TAAPRSRSHDLEAVPYLEGLTTSLRGSCN--------EDPSSDPSSSPDSDSATPDDTSN
SSSVDWDTVERQE-EA-PSWDELAVMIRRRPQ-----EGPRADSSQKAPSLLTRSPVGG-
DTAGQKKEGESFCQVGSHGDGL--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------G
-------GAWTPPLTLSSSVFSPDTGGGGQSAGQHWAKLRGENGF-SLERHRSTLTQASS
MTPHSGPRSTTPRASP---AQRDTAQAAST-----HET------------------PRAS
SPHRITQRDTSRASSTQQDTSRASFTQRNTPRASSP------SRSTQQDNPRTSS-----
-----------------------------------NQQNNPKYSSPPKATQQDNPRTSST
QQDNPQSSFPTCTPQWDNPRTPCARRDDPRASSPNKATQRDNPRTSCAQQDDPRA---SS
PNRA-TRDNPRISCAQRDNPRASSPNRTTQQGNPRTSCAQRDNPRTFSQI--KATQQDNP
RMS----CAQRDDPRASSPSRA--------------------------TQRDNPRTSC--
----------------------AQRDDPRTSSPS--RATQRDNPRTS----CAQR-----
-----------------------------------------------------------D
DPRSSSPSR------------------------ATQKDNPRTSS----AQRDNPRASSPS
RATQRDNPRTSCAQRDDPRASSPSRATQKDNPRTSCA----QRDNPRASSPNRT------
-----TQRDNPRTSCAQRDDPRASSPNRTTQ------------------------RDNPR
TSCAQRDDPRASSPSRASQKDNPR-TSIPQ-----------------------NIPRSSS
TQQDKPKTSCT-------------KQDNLRPTRTQRDRTQSFSFQRDNPGTSSSQCCIQK
ENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQN
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPVYPAACGV-------PLTYPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPHAPESESPHHEPPYIPPAVCIGHRDAPQASSPPRHTQFDPFPFLPDTSDAEHRCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTENVVPSMDSLHERPQIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSVPPGETRHNLEREEYTVLADLPP
PRRLAQRQPGTQAQRSSGGRTRSPGRTEVERLFGQECRKSEAAGAFQAQDEGRSQRPS-Q
-----GQSQLLRRQSSPAPSRQVTKRPAKQ---AELTWRSQA--EPPHSRS-PEKRPEGD
RWLQGSVPPPRTSARTPERELQTQ----------RPLESGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG-----------------------AAKAL---
--------EGAWGGPPGEYR-E-----------------SWGQPEAWEEAAT--------
-----H--------EPPRELGKRS-------PLTSPPENWGGPTESSQSRHPGTPTTVGW
GAEGACPYSHGPERRPELDWRDLLGLLRAPGEGAWVR---------LP--RLDWEGLLEL
L-------------QARLPRKDPAGHRDDLARA---------SGPEMGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPAPLPQSPA------------QSPSPACTSTQWPK-
--TKVTRGPATVTLAGLEQ-TGPLGS--TAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPGEPP----SPSLTTTSTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHNYGTQKGPLKAGEQR---AGVEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKQEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----LRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGTPSDS----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSAPRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRGFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSPG-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MTPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVHTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSECNKENTLHGCGTQKGSLKIGEQR---TGSEFIGRG-GPRRLDGPRPS
LDYVELSPL------TPSSPQRVRTLSRST-----PERPAKQEDLERDLAQRSEERRKWF
ESTDSKT------PE-TPSGDG-----PRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQGHSERRGPPSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNASRPQENSHIPPGYISQEACERSLAEMESSHRQVMEQLQRHHERELQRLQQEK
-ELLLAEETA---ATASAIEAMKKAYQEEL-SRELSRTRSLQQGPDG-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TQQAEERELTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSSERSACELEVLLRVRENELQYLKK
EVQSLRDELQVMHKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

----------MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQ--ACSQEPHSPSS
AEAPYCDLPRCPPALQDPLRTTTCVGQSVHSLGLGLGQEPQR-IWSPTTALPAEGP----
AAAPKNRHQDSEGIPYLEGLACSSCTDDNKNKDEDEDEDPNSNTSSSQD--SNTPHDTSN
--SVDWDTAERPG-VV-PSRNRLTEMIPRRPQ-----EGLRADSARKA----TRSPARG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------NSGSGGQSAGQHWAKLRSESGYFSLERQRSGQTQASS
GTPPSGPRGTT-QASS---AQRDVFQAAPAQ-----------------------EAPQTS
SLPRNTQRDTQRST----------SRTSSPSRVSQRDT------PRVMSTQRKN------
------------------------------------------------------------
------------------------------------------------------------
-------------------TPLSSPLRATP--------------E---------------
------------------------------------------------------------
-----------------TLKISAPEDGTH-------------------------------
-------------------------------VTPSPCVQDSSLNRTSQRDSSRTPCIQRD
NPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPR----AQRDNPRAASPN
RTTQRDSPRT--------------------------------------------------
-------------PCAQRNN--------------PRTPCAQRDNPRASSPNRTAQRDNPR
TPCAQRDNPRT--------------SCTSQ-----------------------NTPRTPS
TQADKTTASCS-------------KWEHLRSACTQRDNP--RTF---------SQGCTQK
DNPGPPSPRRATQGSNSRNPSPHRTNKDIPWASFPLRPTQSDSPRT-----SSPSRTKQN
QVPWASISLRPTQGDKP-QTSAPTRLAHNDPPQQYSPSL----ATTS-SSSHNPGHSSAS
RTSSPLHAAPRGA-------PQTSLESSQPPCTVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEPS-FFQDLPRASTESLVPSTDSMHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSIDSLHGCPLLPP--QVCI
GHRDAPRASSPPRHPPSDIGLLAPSPPPGSS-GSRGSAPPGETRHNLEREEYTMLADLPP
PRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPS-Q
-----AQSQL-RRQSSPAPSRQVTKPSAKQ---AEPTRQNRT--GPPHPKS-PDKRPEGD
WQLQRTSPPARTPARPPERKAQIE----------RHLESGHTGPRQSLGG----------
WQSQERLSGPQSPNRHPEKSWGSQEEGPS----LGGWPELE--GPS----------L---
--------EGIWRGPPQEHRERW------------------GHSGAWEEPPS--------
-----NGIQGA----PPRGQGRLQELSRPHQPTPSSENSWAGPAECSCALQPEASTAVGW
RAEGTSPHQCSAERPPDLDWRDLLGLLRAPEDGAWTR---------LP--RLDWEGLLEL
L-------------QARLPQKDPARHWHDPAKA---------SGPELGSSGTEDTLKTE-
-LQTQPEGRA---KATLANGH--RPGQQSESPA------------QLPSPACTSTQWPT-
--TKVTSGPETSPLAALEQ-IDHLESHSP------PDLEFQPEEPEAS------------
----EPSRGEDSRAVQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PALF
NPY------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYGTQKSSLKIGEQR---TGSEVIGRG-GPRKVDGPRPS
LDYVELSPL------TPSSPQRMRTLSRST-----PERPTKQEDLERDLAQRSEERRKWF
ESTDGRT------PE-TPSGDG-----SRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQAHNDRRGPTSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPES-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------PHGHSGAGGAEGRRGLERQQYSVLADLPK
PKRLGQRDAA--V--RYGSRTLSPGRVEVERMFGCERRKSETLEAFQALEEGRVDRLDGK
TPVPPSKGHLTRRRSSPNLPREVRLGCTAGPHPSSLEQRSRDPKERRRS-PSPARHPEKA
GRTRGD--------------------SPRPASPAWLLERGSPSPRS----------ASPA
RRPERRAGEPLNPPCRAEKSWRSRGEPLSRA-GPPPWALSPGRRTESSRKSQKDISPPSL
VRGAE--RQRVKAGEPLQPA-------GPR---------KAASECSWQSLR---------
--E-K-LTSSQPGKGTGGDCKGRGKPLRPTSPTRALEQDWRSRGDARQAQAWDKDRKRQE
----APVCRADAMRQLERDWKSPARCLDP---------D--SLGSSASPGK---------
----LYCP--------------PGTGRREDAFFPG---------PR--------------
--------------------QETDAPIWET----------------------EQA-REE-
--PKALNSPCTTGP----------------DRPTC-------------------------
--------------------------------------AR------------------LL
---SVPA------------------LSSGLAPQGT---HLAPPGTENPCV-GHSKMVILC
FVFQPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLRYYRDSN
AEEADDLDGEIDLRSCTDVTEFAVQRNYGFQIHTKDAVFTLSAMTSGIRRNWIEALRKNV
RPVSAPDVTKLPDCDKEN-LRNSAPQKGSLRAEEQQRPGSGSEGNSKG-THWKADGQRHA
FDYVELSPLPQDP-GNQGSLQRTKGSLRI-----SERAPKY-EELERDLAMRSEERRKWF
ESPDGRVPNSEGPAGDPSRRAG-----EQDLPTAPLSEEQRARLNEEIEKKWLELERLPL
KDLRRVPLTTLLNQSKGGQGDT-SEALKKE------------------------------
-----------------------------------------------IQSLRAQLESCRA
RNESLREAAKSQGDSHVPRGYISQEACERSLAEMESSHQQVMEELQRHHQRELERLRQEK
-ERLLAEEAA---ATAAAIEALKKAHREEM-NKELGRTRSFQQCSSL-----------PE
ALQKQHQ-LDVESLKRELQVLSEQYSQKCLEIGEL-TQKAEEREQILERCQREGKDLLQK
NQELQTRLSDEIGKLRSFISSRGS-----GDRASHNNERSSCELEVLLR-----------
------------------------------------------------------------
-------

----------MSMEQDTRALLPTQGTAWATASAPVARLQGPQGDSHQ--ACSQEPHSPSS
AEAPYCDLPRCPPALQNPLRTTTCVGQSVHSLGLGLGQEPQR-VWSPTTALPAEGP----
AAAPKNRHQDSEGIPYLEGLARSSCTDDNDNKDE--DEDPNSNTSSSQD--SNTPHDTSN
SSSVDWDTTERPG-VV-PSRNRLTEMIPRRPQ-----EGLRADSARKA----TRSPARG-
DTAGQRKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------NSGSGGQSAGQHWAKLRSESGYFSLERQRSGQTQASS
GTPPSGPRGTT-QASS---AQRDVFQAAPAQ-----------------------EAPQTS
SLPRNTQRDTQRST----------PRTSSPSRVSQRDT------PRVMSTQRKN------
------------------------------------------------------------
------------------------------------------------------------
-------------------TPLSSPLRATP--------------E---------------
------------------------------------------------------------
-----------------TLKISAPEDGTH-------------------------------
-------------------------------VTPSPCVQDSSLNRTSQRDSSRTPCIQWD
NPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPC----TQRDNPRASSPN
RTTQRDNPRT--------------------------------------------------
-------------PCAQRDNPRAASPNRSTQRDSPRTPCAQRDNPRASSPNRTAQRDNPR
TPCAQRDNPRT--------------SCTSQ-----------------------NTPRTPS
TQADKTTASCS-------------KWEHLRSACTQRDNP--RTF---------SQGCTQK
DNPGPPSPRRATQGSNSRNPSPHRTNKDIPWASFPLRPTQSDSPRT-----SSPSRTKQN
QVPWASISLRPTQGDKP-QTSAPTRLAHNDPPQQYSPSL----ATTS-SSSHNPGHSSAS
RTSSPLHAAPRGA-------PQTSLESSQPPCTVCIGHRDAPRASSPPRYFQYDPFPFFP
DPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADN--ESPQ
HDPPQFPPPVCIGYRDAPRASSPPRQF-PEPS-FFQDLPRASTESLVPSTDSMHEPPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSIDSLHGCPLLPP--QVCI
GHRDAPRASSPPRHPPSDIGLLAPSPPPGSS-GSRGSAPPGETRHNLEREEYTMLADLPP
PRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPS-Q
-----AQSQL-RRQSSPAPSRQVTKPSAKQ---AEPTRQSRT--GPPHPKS-PDKRPEGD
RQLQRTSPPARTPARPPERKAQIE----------RHLESGHTGPRQSLGG----------
WQSQERLSGPQSPNRHPEKSWGSQKEGPS----LGGWPELE--GPS----------L---
--------EGIWRGPPQEHREQW------------------GHSEAWEEPPS--------
-----NGIQGA----PPRGQGRLQELSRPHQPTPSSENSWAGPAECSCALQPEASTAVGW
RAEGTSPHQRSAERPPDLDWRDLLGLLRAPEDGAWTR---------LP--RLDWEGLLEL
L-------------QARLPQKDPARHWHDPAKA---------SGPEQGSSGTEDTLKTE-
-PQTQPEGRA---KATLANGH--RPGQQSESPA------------QLPSPACTSTQWPT-
--TKVTSGPETSPLAALEQ-IDHLESHSP------PDLEFQPEEPEAS------------
----EPSRGEDSRAVQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PALF
NPY------------------------------------------------LLSL-GVLR
-WQRPDLLNFKKGWMSILDEPGE-----------------WKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDCNKENTLHGYGTQKSSLKIGEQR---TGSEVIGRG-GPRKADGPRPS
LDYVELSPL------APSSPQRMRTLSRST-----PERPTKQEDLERDLAQRSEERRKWF
ESTDGRT------PE-TPSGDG-----SRRGLGAPLTDDQQSRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQAHNDRRGPTSDS----------------------------------
----------------------------------------HEALEKEVQSLRAQLEAWRL
RGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPES-------------
-LRKQHQ-LDMEALKQELQVLSERYSQKCLEIGAL-TRQAEEREHTLRRCQQEGQELLRH
NQELHSHLSEEIDRLRSFIASQG-----TGNSCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEA
VRNSLAE

-MEEVPGDA-LCEHFEANIL-----------TQNRCQNCFHPEEAHG--ARYQELRSPSG
AEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRG---PSPSAGLPEEGP----
TAAPRSRSRELEAVPYLEGLTTSLCGSCN--------EDPGSDPTSSPD--SATPDDTSN
SSSVDWDAVERQE-EA-PSWDELAVMIPRRPR-----EGPRADSSQRAPSLLTRSPVGG-
DAAGQKKE----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------DTGGGGRSAGQHWARLRGESGL-SLERNRSTLTQASS
MTPHSGPRSTTSQASP---AQRDTAQAAST-----REI------------------PRAS
SPHRITQRDTSRAS------------------------------STQEDTPRASS-----
-----------------------------------TQWNTPGASSPSRSTQLDNPRTSST
QQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSS
PNRA-TRDNPRTSCAQRDNPRASSPNRAT-------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------RDNPTTSCAQRDNPRASRTSSPNRA-TRDNPR----TSC----------AQQD
NPRASSPNRTTQRDSPRTSCARRDNPRASSPNRTIQQ-----------------------
-----------------------------ENPRTSCA----RRDDPRASSRNRT------
-----IQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRAT-RDNPR
TSCAQRDNLRASSPIRATQQDNPR-TCIQQ-----------------------NIPRSSS
TQQDNPKTSCT-------------KRDNLRPTCTQWDRTQSFSFQRDNPGTSSSQCCTQK
EKLRPSSPHRSTQWNNPRNSSPYRTNKDIPWASFPLRPTQSDGPRT-----SSPSRSKQS
EVPWASIALRPTQGDRP-QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS
RTSSPVYPAAYGA-------PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP
EPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ
HEPLQLPAPVCIGYRDAPRASSPPRQA-PEPSLLFQDLPRASTESLVPSMDSLHECPHIP
TPVC-------IGHRDAPSFSSPPRQA-PEPSLFFQDPPGTS------------------
-----------------------------------MESLAPSTDSLHGSPVLIP--QVCI
GHRDAPRASSPPRHPPSDLAFLAPSPSAGSSGGSRGSAPPGETRHNLERDEYTVLADLPP
PRRLAQRQPGPQAQCSSGGRTRSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPS-Q
-----GQSQLLGRQSSPAPSRQVTKLPAKQ---AELTRRSQA--EPPHPWS-PEKRPEGD
RQLQGSPLPPRTSAGTPERELRTQ----------RPLESGQAGPRQPLGV----------
WQSQEEPPGSQGPHRHLERSWSSQEGGLG----PGGWRGCG--EPS----LGAAKAP---
--------EGAWGGTPREYR-E-----------------SWGQPEAWEEKPT--------
-----H--------ELPRELGKRS-------PLTSPPENWGGPTESSQSWHSGTPTAVGW
GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWAR---------LP--SLDWEGLLEL
L-------------QARLPRKDPAGHRDDPARA---------LGPELGPPGTKDVPEQE-
SHS-QPEGWA---EATPVNGH--SPALQSQSPV------------QLPSPACTSTQWPK-
--IKVTRGPATTTLAGLEQ-TGPLGSRSAAEGPSLPELQFQPEEPEES------------
----EPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDR-------PTLF
NPF------------------------------------------------LLSL-GVLR
-WRRPDLLNFKKGWMSILDEPEEPP----SPSLTTASTSQWKKHWFVLTDSSLKYYRDST
AEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTV
RPTSAPDVTKLSDSNKENALHNYSTQKGPLKAGEQR---AGSEVISRG-GPRKADGQRQA
LDYVELSPL------TQASPQRARTPART------PDRLAKHEELERDLAQRSEERRKWF
EATDSRT------PE-VPAGEG-----PRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPL
RENKRVPLTALLNQSRGERRGPPSDG----------------------------------
----------------------------------------HEALEKEVQALRAQLEAWRL
QGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEK
-EWLLAEETA---ATASAIEAMKKAYQEEL-SRELSKTRSLQQGPDG-------------
-LRKQHQ-SDVEALKRELQVLSEQYSQKCLEIGAL-MRQAEEREHTLRRCQQEGQELLRH
NQELHGRLSEEIDQLRSFIASQGM-----GNGCGRSNERSSCELEVLLRVKENELQYLKK
EVQCLRDELQMMQKDKRFTSGKYQDIYVELSHIKTRSEREIEQLKEHLRLAMAALQEKES
MRNSLAE

Query Results

"ENSGT00530000063678_0"

ENSGT00530000063678_0