ENSGT00530000063607_1 : Linker Region Query Results

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
DYMDSNKYIDHLLTQLREQHRSLWREKLAVARLQQEVAQRTNEGAMREKLIHELEEERHL
RLQSEKRLREVTLESEHNRVQMHSLQQRFSRMEETVRNLLQSQASPEQKREETVNIM-VY
QERLSEDERKHQQALSDLHLHVAVDEDSRSESSSTDGGKGKTKLLLERLKALEAENSALA
LENENQREQYEKCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRA
RPASDVLLQER------------------------------------QQN-AKPRTP---
ALKCSG-SGLVEPGHL-CPRNSCSSS--DLSPSSTCSEYSSGSSYTWHD--GKHLGKRQS
SQNWDKRLSIDSS----------LPSGFTSSADELPPTRIKESHILEGLRKLQRRRVL--
LEPP-SMITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPYKPPGTGSPSKEPHTTFVYD
TDSHEEADDDPSSLALQQADPSQGC---RIPGRKLTHSVSDSLFGLELRGKHLLEGTSS-
GNSSERPERLTQCVSNCPLETKMYSSVHQPRVQRERDAHSQGHNHMAPHAQLSDTDENEA
LDELHIESSDERSPSDSSLTADTGKSVENLDILLGFGKLECGSQE-EDKEQLPS---HSE
IRPATLGLITQHRVVKRTSSEECITVIFDAENGEPVEFSSHQTGVVTVTRAEISISPALT
GSTAENTELLPQGITYLQTQAT--TKDYSFPGRPREETEKNIPRDDE-GSVAL------A
LPDSFSPRTTAIQNSPHMKLTKPIHSMLYQSDSRSLASMGIFQKQGLTKIPARGKSSPQK
SKTT-EPEASTVPPSSSPVNPEKSTPFPIGKLSQRTKADSSGPLFD-RRVDPHIPKQPTL
LSYGP-RVSNKKNWASYLKNQVPEAR--SRPLLRPDDSRDTPVRDKNCGLGSE---SAVS
SPSL-PPPPGRSVSLLARPSYDYPPPKSSAKPEPRVPSDTAKTEVKSPKLKGSFAPVTSS
GQTT-SEVLRKKPAMALKKSIFPSCLPS--TEVLMHTQYPDHTPSGSCAIIAPGPQKVSP
KRG-VPKASTQQTLGTIH--PNRGLWTPKTCPSTHELLEIASSKSLSPKRKGLLNDS-VP
IS----------CQPSFSGTSESPSSQVNSPSPSSQLPSKSHTTTQDSQNPPEKVLKTRL
PVGLKLLMKSPQLARKSSLVPGKQEKDSLNEASKSS-VAVSRNKPEDSRTPESLETT-GD
--ERNTSLLDLQAAVSLTRGIPLEPAMPESSESGIPGADGGDGVENRPVKRSFSS-SKPH
LKPALGMNGAKARSQSFSIHSGDKPSIPS-TEGPGKIRTHIITNTAERGNSLTRQNI--L
TEGSPSKSPSVPVS--ENIPDTGRNLGHSFSRQGSLGSTESS-SSQHGSPSKLPMRITPR
SEGLFTTLGMEDQQIYDQGEGPR--VDVHEDPGNDYDRCLL-I------------P----
-TSGTQVLQATGRVELSSHLGTSRISKL-ETSGRSS-DVSTTETNAVSPEAPLSPSIEEK
VMLCIQENVEKGQVQTKSTSMETKPKP-GPSFTNWFGFRKSRLPALSSRRVDASKTKMEK
KDVK--------LKSERKKEKKKPEEQRKTENELIRG-AKS--PEIPENGLQNKRNLKAS
QDVYSLTKFEPRSRPSA-AVCLTEDTFMTELLNRVDKKGTPQTENGSNSVSCKSMLKGTS
QGSCFASSSISIQGSQKKIIKAKVNVEIPRDSLVKNVNE-DLQENEDDRIGD-----SAF
QSHVIESNCLMRTLDSGIGTFPLPDSGNRSTGRYICQPDSPEDHQPLLSLQPAPSTASPA
RAQTLEREVPSSTD-SQLSSDSTIVHSISDPIMTARVKRVPQSHLPKPTSSGKTIFQKLN
EVE-SKPQNCSTLDYTEDPM--TREPHPGWRSEAGT-VETQELK----------------
------------------------------------------------------------
-----------------------------QVEETKEAPGHKLSKISLE-TFSKFNSNTVI
LLEK-ENSPNKVEGQKEGKEKNEEVSLSSSDRPG-VDNMESLSDSLYDSFSSCASQTSND
A

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------AENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSILFQQRV
RPASDVFLQEH------------------------------------LQN-AKSGTP---
ALKHSG-SGLVIPDHL-CPGNSCSS-S-ELSLSSTCSECSSGASHTWQD--RKLLGKRQS
SQNWDKRLNIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIKN-S-TLKESPHGQPPGLGIPCKDLHHSFTYD
ANSHENTDEESPPSALLQSAPGQGH---KMQGSKLTHSVSDSLFSWEPHGKYFSEGTAS-
VYTREMPERLVRCASHCPLERKLCPSMHLPWVQRDRDPHGHGHGRVALTLQLSDTDDCDT
LNELHIESSDERSPSDLSLTGDTDKSMENLE--VGSGKSECGSCD-VEEEECLT---HLE
TKPKTFGFIRQQRVVKRTSSEECVTVVFDAENGEPVEFSSHQTGVVTVTRDEISINSTPP
GPS-ELTQLSPQGITHLQPGAT--ARDCPFRKRPEEETAKNIPKDKN--SIAT------A
LTDSFGSRAIVTQNSSRPVITKPTQGGAWQSNSRPGANTGVCAKQGLTKIPSRAKSSPQK
SKRA-EPVPAMLVPSSALVALEKTPASPPGKLAQCTKMESPGSLHD-AQPASHIPKHPTQ
LPHVPSNVSNKKNWVQCPKSQAPGIQ--SQHLMGSGDCGESPMKAKRCGSGPE---SRVR
SPSP-PPPPGRSVSLLVRSSYDHTPLPSPGRPETRGPRDAVSAGLKSPLLKGSSVPVISS
SPAV-SELQQKKPSLASKKPAFPPDLPP--TDAVVHTQYPEHTSSSSFAAMAPGPPKVSP
KRG-ISKPSPHQALGTTH--VDAELQTPKTCPSTYELLEGASSKSLSPGRKGQLSAS-SM
IP----------HRPSFSGANEPLTPQVNSPSPS-SSSCRSQDTSQSRQNPPEKGPKTRL
PIGLKVLMKSPQLLRKTSMAPGKQEKDSLNEASRSS-VTLNKSNPEDSRDPASLEAS-GE
--ERTTALLGPQGLDSLARGLPLESSLPESLESSISRADGRDGVESRSVKRSFSS-SKPH
LKPALGMNGAKARSQSFSIHFGEKPSQPP-TEGPGKIRTQIITNTAERGNSLTRQNI--S
MEGSPSKTPSVSTS--DNLPNVGRPLEQSFSRQGSLCSTGSS-SSQHGSPSKLPLRMLTR
PEELPT-PGVGDQQIYTQEECPGGDV-VREQSSSAHHRHPS-T------------P----
-PDCPQSLHIPGRLQHPGNLETSGISKL-ETSGRHP-EASPTGPGIVSPEAPLTPSIEEK
VMLCIQENVEKGQVQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRMETSKSKVEK
KDTK--------LKSERKKEKKKAEVQSKLESELNRAGTKAADGRSSDGGSRTTQNLKAS
QDIYNEMKLEPRNRPSP-AVCSTKDSFMTELLNRVDKKAALQTESGSKGVSCRSVLEGTS
QGSCFTGSSVSTQGSQKKNIKTKVDMEKPRESLGAEVNEEDEREDEEDRVAD-----SAL
QSHVIESNCQMRTLDSGIGTFPLPDSGNRSMGRYICQPGSPEDTEPLPPLQPAPCLASSA
RAQTLEREVPSSTD-SQNSSESTIIHSISDPSMTARGMRP-QSHLPKPTSSGKTSFQKQN
EAE-SKTQPGPSFDSAEDAV--ASEPLSGWRGEDAT-TETQELKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISLE-SFNKFNSNTVI
LLGT-EKSPSTVKGQEEG--RKTDAPSGDSAKPG-VDNVESLSDSLYDSFSSCASQGSHD
A

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERNRSLTQSR-TDAEVHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIR-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDPSTLALLQAVPNQSC---RPHGSKLTHSVSDSLFGWETNRKHFLEGTSS-
VYPKESPEKLTSCTSSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNET
FDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGLGKSLCGSPE-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPT
GPKAEHTELLPQGIACLQPRAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPARGKSSPQK
SKLM-EPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFE-LRPDPHIPKHPAQ
LPHSS-RMPSRRDWVQCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGAK
SPSP-PPPPGRSVSLLAKPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGTSAPVISS
NPAT-TEVQRKKPSVAFKKPIFTHPMPS--PEAVIQTRFPAHAPSSSFTVMALGPPKVSP
KRG-VPKTSPRQTLGTPQ--MDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGVNESPSSQVSSSSSS-SSPAKSHNSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASME-ITAG
ER--NVTLLDSQAQGNLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSS-SKPH
LKPALGMNGAKARSHSFSTHSGDKPSTPP-MEGSGKVRTQIITNTAERGNSLTRQNS--S
TESSPNKAPSAPML--ESLPSVGRPSGHPSSRQGSLGSSGSF-SSQHGSPSKLPLRIPPK
SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDISKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKD-TKS--ADNPDGGLQSKNNQRTP
QDIYNQLKIEPRNRHSP-VACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANE-NLQEDEDDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLTLQSALSAVSSM
RAQTLEREVPSSTD-GQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQN
EAE-PRPQTCSSFGYAEDPM--ASQPLPDWGSEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEDTVNIM-VY
QEKLSEEDRKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDE-------------DLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SLITKWGYKDCMNSNEGIYSPGIK-SS-SLKGYPPCKAADPGSPCKEPHKTFVYD
LDSHDDADDDSSTLALLQAVPNQSY---RPHGSKLTHSVSDSLFGWEMNRKHFLEGTPS-
VYPRERPEKLTSCASSCPSERKLCPSVQVPQVQR--EPQGQGHGRLALHIQLSDTEDNEM
LDELHIESSDEKSPSDVSLAADTDKSMENLDVLVGFGKSLFESPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRKEISINSAPT
GPKAEHTELLPQGIACLQPGAA--ARDYTFLKRSEEDTEKNIPKDHV-DNVSR------V
STESFSSRTVTQS-SQQQKLVKPTHTVSCQSHSRSSAPVGIYQKQNLTKIPARGKSSLQK
SKLM-EPEATALLPSSGLVTLEKPPALAPGKLTRFMKTETPGPLFE-LRPDPHIPKHPTQ
LPHSS-RMPSRRDWVQCPKSQTPGSR--SRPDIESNDSGEPPTRDEHCGSGLK---AGAK
SPSP-PPPPGRSVSLLARPSYDYSPAPSSTKSETKLPSEIARTPFKSPLLKGTSAPVISS
NQAT-TEVQRKKPSVAFKKPVFTHPMPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-VPKTSPRQTLGTPQ--MDAGLQTPRNSPSTHEPLEITSSKSISPVRKGQLNDR-AS
TS----------PKPSFLGVNESPSSQVSSPSSS-SSPSKSHNSSHGCQSTHEKGLKTRL
PVGLKVLIKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPGNSKNPASVE-TTAG
ER--NVTMPDSQAQDSLAEGLPLETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSTPP-MEGSGKVRTQIITNTAERGNSLTRQNS--S
TESSPNKVPSAPMS--ESLPSAGRPLGHPSSRQGSLGSSGSS-TSQHGSPSKLPLRVLPK
AEGLLTPLGKEDQQAYAQGECPS--VAVLGKPDGDCHRCPP-T------------P----
-AGFPEALQSPGRTQHPSTFETSSISKL-ETSGRHP-DASATVTDAVNSEAPLSPTIEEK
VMLCIQENVEKGQVQIKPTFVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNKQLKSERKKEKKKPELQCEIENELIKD-SKS--ADNPVSGLQSKSNRKTP
QDIYSQLEFEPRKRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLTGSSINTQGNHKKNMKIKADMEVSEDSLIKEGNE-NLQEDEEDAVAE-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDTEPLLPLQSAFSAASSM
RAQTLEREVPSSTD-GQRPADSAIVHSASDPIMTARGMRPLQSCLPKPASSGKGSTQKQN
EAE-PRPQTCSPFGYAEDPM--ASQLLPDWGSEDTA-SGTQDKV----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSVPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYVEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEDNVNIM-VY
QEKLSEEERKRKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-ADAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPANELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SLITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKAADPGSPCKEPHKTFVYD
LDSHDDADDDSSTLALLQVVPNQSY---RPHGSKLTHSVSDSLFGWEMNRKHFLEGTPS-
VYPRERPEKLTSCASSCPLERKLCPSVQVPQVQR--EPQGQGHGRLALHLQLSDTDDNET
LDGLHIESSDEKSPSDASLTTDTGKSAENLDVLVGFGKSLSESPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRKEISINSAPP
GPKAEHTELLPQGIACLQPGAA--ARDYTFLKRSEEDTEKNIPKDHV-DNVPR------V
STESFSSRTVTQN-SQQQKLVKPTHTVSCQSNSRSSAPVGIYQKQNLTKIPSRGKSSPQK
SKLM-EPEATALLPSSGLVTLVKPPALAPGKLTRFMKTETPGPLFE-LRPDPHIPKHPTQ
LLHSS-RMPNRRDWVQCPKSQTPGSR--SRPDIESNDSGEPPTRDEHCGSGLE---AGAK
SPSP-PPPPGRSASLLARPSYDYSPAPSSTKSETRLPSEIARTPFKSPLLKGTSAPVISS
NQAT-TEGQRKKPSVAFKKPVFTHPMPS--PEAVIQTRCPAHAPSSSFTIMALGPPKVSP
KRG-VPKTSPRQTPGTPQ--MDAGSQTPRNSPSTHEPLEITSSKSVSPVRKGQLNDR-AS
TS----------PKPSFLGVNESPSSQVSSPSSS-SSPSKSHNSSHGCQSAHERGLKTRL
PVGLKGLIKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPGDSKNLAGVE-TTAG
ER--NVTIPDSQAQDSLAEGLALETALQESLESSVPGSDGRDGVGNRSMKRSLSS-SKPH
LKPALGMNAAKARSQSFSTHSGDKPSTPP-MEGPGRVRTQIITNTAERGNSLTRQNS--S
TESSPNKVPSAPMS--ESLPSAGRPLGDPSSRQGSLGSSGSS-TSQHGSPSKLPLRVPPK
AEGLLAPLGKEDQQAYAHRECPS--VAVLGAPDGDYHRCSP-T------------P----
-TGFPEALQSPGRTQHPSTFETSSISKL-ETSGRHP-DASATVTDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFANKQLKSERKKERKKPELQCELENELIKD-SKS--ADNPVGGLQSKSNWKSP
QDIYDQLEFEPRKRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLTGSSINTQGNHKKNMKIKANMEVSEDSL---------------------------
------SNCQMRTLDSGIGTFPLPDSGNRTTGRYLCQPDSPEDTEPLLPLQSAFSAASSM
RAQTLEREVPSSTD-GQRPADSAIVHSASDPIMTARGMRPFQSRLPKPASSGKGSTQKQN
EAE-PRPQTCSSFGYAEDPM--ASQLLPDWGSEEAA-SGTQDKV----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSVPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

ME------GKR-QLD----KRDF-GKRLSLDSSL-------------------------V
DYMDSNKCIEHLLTQLRQQHRSLWREKLAVARLQREVAQKTNQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMRGLQQQFSRMEETVRSLLQSQGSPEHKREEPSKIT-AY
EERVSEEERKHQEALADLQV--VVDEDSRSENSSTDEGKENTRLLLKRLKALEAENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRV
RPASDVLLREH------------------------------------LQN-AKSGTP---
ALKHSG-LGGVIPDHL-CPRNSCSS-S-ELSLSSTCSEYSSGSSYTWHD--QKLIGKRQS
SQNWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGTKN-S-SLKEYPPCQPPGIGIPCKDLHHSFIYD
ANSHENADEDSPPSALLQAAPSLSC---RMQGSKLTHSVSDSLFSWEPHGKYFSEGTVS-
VYTREMPERLVRCASHCPLERKLRPSMHLPWVQRDRDPSSQGHGYVALTLPLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDKSMENLD--VGSGKSECSSRD-VEEEECLT---HLE
TRPKTFGFIRQQRVVKRTSSEECVTVVFDAENGEPVEFSSHQTGVVTVTRDEISINSAPA
EPS-ELTQLSPQGITHLQPGAI--ARDCPFQKRPEEETEKNIPKDES--SIPI------A
LTDSVGPRTIVTQNSPRPKLTKPTQGVAWQSNSRPGANMGVYAHQGLTKIPSRGKSTPQK
SKLV-EPVPAMLLPSSGLVTLEKTPASPPGKLPQCKKTESPDSLCD-VKPESHIPKHPTQ
LPHVT-KISNKKNWVQCPKSQAPGIQ--S-HLMGSGNHGESPMKAKHCGSGSE---TRVR
SPSP-PPPPGRSVSLLVRPIYDYPPLLSPAKPETRVPRDTVSPVVKSPPLKGASVPVISP
SPAT-SEVQKKKISVASKKPTFPPAPPP--TDAVVHT------SSSSFDVMAPGPPKVSP
KRG-IPRPHPHQALGTTH--MDTELQTPKTYPSNQELLEVASSKSLSPGRKGQLSDS-SM
IL----------HRPSISGTNESLTSQVNSPSPS-SSSCRSQGTSQSRQNPPEKGPKTRL
PVGLKVLMKSPQLLRKTSVVPGKQEKDSLNEASRSS-VTSNKSNPEDSRDPASLEAS-GD
--ERKTALLGPRDLDSVAGGLPLESALPESLESSISKADGRDGMENRWVKRSFSS-SKPH
LKPALGMNGAKARSQSFSLHLGEKPSTPP-TEGPGKIRTQIITNTAERGNSLTRHNI--S
MEGSPSKSSCVSTS--DKLPNVGRPVEQTFSRQSSLCSTGSS-GSQHGSPSKLPLRMLTR
PEELTT-PGVEDQ----QEECPGMDV-VHEQSSSDHHRHPS-T------------P----
-SDCAESLQIPGRMQHPSNLETSGIYEL-ETSGCHP-EASPTGHGIMSPEAPLSPSIEEK
VMLCIQENVEKGQAQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRTEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKIESELNR-GTRVADGQSSDDGVRGTHNLKAS
QDIYNEMKLEPRNKPSP-AVCTTKDAFMMELLNRVDKKAALQTESGSKGVSCRSVLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNE-DLREDEEDRLAD-----SAL
QSHVLESNCQMRTLDSGIGTFPLPDSGNRSMGRYICQPDSPEDTEPLPPLQPASSITSSA
RAQTLEREVPSSTD-SQSSSESTVIHSISDPSVMARGIQALQSHLPKATSSGKTSFQKQN
EAE-SKTQTGPSFEYVEDAV--AREPLSGWRGEDAA-TETQELKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISPE-SFNKFNGNTVI
LLET-EKSPSKVKGQKEEKGKNIDASSSNSARPGGDNNVESLSDSLYDSFSSCASQGSNE
A

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MATFLPCFLKVANQVVQALLTQKDLREECVKLKTRVFDLEQQNQTLSILFQQRV
RPTSDLLLQKQ------------------------------------QLN-AKSGTP---
TLRCPG-LGVVVPSHL-CPRNSYSSS--ELSLSSTCSEYSSSSSYTWHD--GKNLRKRQP
SQKWDKRRSIDSS----------LPSGFASPADELPPTRIKENHILEGLRKLQKQKVL--
LEPS-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYSSCKPPGVGIPCQESHKAFISA
ADSHEDADDDSSSLALLQAVPNPSC---RLHGSKLTHSVSDSLFGWELSGKHFPGGTSS-
AYPRERPEKLTH-ASKCPLERQLCPRVQVPLLQRDRDPHSQGHDHAALSLQLSDTDDNET
LDELHIESSDEKSPSDLSLTADTDKSMENLDILMGFEKSEHGSPD-EEEKQVPT---QLE
TRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPFEFSSHQTGVVTVTRNEISINTPPS
GLTAEHTELLPQGIAHLHPEAA--ARDCPFLKRSEEETKKNIPTGGV-DSVSS------A
PTGPFSSRTVTQN-VPQQKLATPTHSISCHSNSRSVAPIGICQKQNLTKIPARGKSSSQK
SKII-EPEGSTLVPSSGPVTLEKSPVLPPGKFAQLIKTENVGPLCH-VQPDSHIPKLPTQ
PSHCP-KVSSRKDWAQCSKSQAPGLT-RSRLLIEPGNGGEPPTRDKHCASGLE---AGVT
SPSP-PLLPGRSVSLLVRPSYDCPSPPSSTKPESRAPSETERTVFKSPMLKGASAPVISS
NQAT-GEVQKKKPSMAFKKPVFPHVLPS--TETVIYPGCSSHAPSRSFPMITPGPPKASP
KRG-VPKTSPHQTLGTTH--MDTGLRVPKTCPSTHEPLEILTSKSMSPGRR-QLNDS-VH
AS----------PKPFFLGANESPSSQVSSSTSS-LSSSKSHSTPHGCQNTHEKGLKTRL
PVGLKVLTKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAPSRPKLEDSGNPSNLEAT-GC
ER--NTLTPGFHAPDRLAEGLPLETVLPESLENGIPEADGRDGIENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSPPA-VEGPGKIRTQIITNTAERGNSLTRHST--S
TEGSPSNTHSAPTS--ESLLCA----GHSFSRQGSLGSTGST-SSQHGSPSKLPLRITPK
SEGLQTQPGTEDQQVYIGGECTS--VVLPEEPGSDHCRCPP-T------------P----
-TDCPRVPQAPGRTLHPSSSETSRTSKP-ETSGRHP-DVSITSTGAVSPEAPLPATIEEK
VMLCIQENVEKGQVQTKATSVEAKPKP-GPSFASWFGIRKSRLPALSSRKMDFSKTKVER
KDVKVLGFGNKQLKSERKKERKKPEVQCEIENELHRD-TNL--AGSPDSGSQSKNNLKTS
QDMYNQMNFEPRNRPSP-VTCSAKDTFMTELLNRVDKKGTQQTESGSNNVSCRNVLKGSS
QGSCLTGSSISTQGSHKKNIKTKVDMEIARDSLVKEANE-NTQEDEEDTITD-----SAF
QNHVIESNCQMRTLDSGIGTFPLPDSGNRVTGRYTCQPDSSEDSKPLLSVQQAPSSASSI
RAQTLEQEVPSSTD-SRLATETAIVHSTSDPIMVARGMQPPQSFLPKPASSGKNSFQKQN
EAE-LTSQTCSSLDYAEDTV--AGKPLPDWGSDGTA-TETQKLKQVEET-----------
------------------------------------------------------------
------------------------KEDPEH----------RLSKISLE-SFNKFNSNTVI
LLEK-ENSVSKVEGQKEAREKNEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
I

----------------------------------------------MFTVVMRFCLVFVQ
EYMDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAVHEKLIHELEEERHL
RLQSEKRLREVTLELERNRAQMRGLQRQFSRMEETVRNLLQSQGPPQQNKEETE------
--KLLEEERKHKESLDDLH--TVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENEKQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKQ------------------------------------QLN-AKSGTP---
TLRCPG-LGVVVPSHL-CPRNSYSSS--ELSLSSTCSEYSSSSSYTWHD--GKNLRKRQP
SQKWDKRRSIDSS----------LPSGFASPADELPPTRIKENHILEGLRKLQKQKVL--
LEPS-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYSSCKPPGVGIPCQESHKAFISA
ADSHEDADDDSSSLALLQAVPNPSC---RLHGSKLTHSVSDSLFGWELSGKHFPGGTSS-
AYPRERPEKLTH-ASKCPLERQLCPWVQVPLLQRDRDPHSQGHDHAALSLQLSDTDDNET
LDELHIESSDEKSPSDLSLTADTDKSMENLDILMGCEKSEHGSPD-EEEKQVPT---QLE
TRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPFEFSSHQTGVVTVTRNEISINTPPS
GLTAEHTELLPQGIAHLHPEAA--ARDCPFLKRSEEETKKNIPTGGV-DSVSS------A
PTGPFSSRTVTQN-VPQQKLATPTHSISCHSNSRSVAPIGICQKQNLTKIPARGKSSSQK
SKII-EPEGSTLIPSSGPVTLEKSPVLPPGKFAQLIKTENVGPLCH-VQPDSHIPKLPTQ
PSHCP-KVSSRKDWAQCSKSQAPGLT-RSRLLIEPGNGGEPPTRDKHCASGLE---AGVT
SPSP-PLLPGRSVSLLVRPSYDCPSPPSSTKPESRAPSETERTVFKSPMLKGASAPIISS
NQAT-GEVQKKKPSMAFKKPVFPHVLPS--TETVIYPGCSSHAPSRSFPMITPGPPKASP
KRG-VPKTSPHQTLGTTH--MDTGLRVPKTCPSTHEPLEILTSKSMSPGRR-QLNDS-VH
AS----------PKPFFLGANESPSSQVSSSTSS-LSSSKSHSTPHGCQNTHEKGLKTRL
PVGLKVLTKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAPSRPKLEDSGNPSNLEAT-GC
ER--NTLTPGFHAPDRLAEGLPLETALPESLENGIPEADGRDGIENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSPPA-VEGPGKIRTQIITNTAERGNSLTRHST--S
TEGSPSNTHSAPIS--ESLLCA----GHSFSRQGSLGSTGST-SSQHGSPSKLPLRITPK
SEGLQTQPGTEDQQVYIGGECTS--VVLPEEPGSDHCRCPP-T------------P----
-TDCPRVPQAPGRTLHPSSSETSRTSKP-ETSGRHP-DVSITSTGAVSPEAPLPATIEEK
VMLCIQENVEKGQVQTKATSVEAKPKP-GPSFASWFGIRKSRLPALSSRKMDFSKTKVER
KDVKVLGFGNKQLKSERKKERKKPEVQCEIENELHRD-TNL--AGSPDSGSQSKNNLKTS
QDMYNQMNFEPRNRPSP-VTCSAKDTFMTELLNRVDKKGTQQTESGSNNVSCRNVLKGSS
QGSCLTGSSISTQGSHKKNIKTKVDMEIARDSLVKEANE-NTQEDEEDTITD-----SAF
QNHVIESNCQMRTLDSGIGTFPLPDSGNRVTGRYTCQPDSSEDSKPLLSVQQAPSSASSI
RAQTLEQEVPSSTD-SRLATETAIVHSTSDPIMVARGMQPPQSFLPKPASSGKNSFQKQN
EAE-LTSQTCSSLDYAEDTV--AGKPLPDWGSDGTA-TETQKLKQVEET-----------
------------------------------------------------------------
------------------------KEDPEH----------RLSKISLE-SFNKFNSNTVI
LLEK-ENSVSKVEGQKEAREKNEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
I

-------------M----TQEGH-LLVHLASASV-------------------------E
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRRSEGAMHEKLMHELEEERHL
RLQSEKRLQEVTLESERNRVQMRGLQQQFSRMEETVRNLLQSQGPPEQKKEETVNIM-VY
QEKLSEEERKHKEALEGLH--MVVDEDSRSESSSVDDGKENTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRI
RPTSDLLLQKLHSRI-LDLSSGDLLSDVERSRSLTQSR-TDVEIHECQPN-AKSGAP---
ALKCPG-LGIVIPGHL-CPRNSCS-SS-ELSLSSTCSENSSGSSHTWHD--GKNLRKRKS
SQNWDKRLSIDSS----------LPSGFASPTDELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SIKGYPPCKPTDTRSPSKEPHETFVYD
TDSHDDADEDSSSLALLQAAPNQGC---RLHSHKLTHSVSDSLFGWELNRKHFTEGVSS-
VYPRESPENRTSCASNCPLERMLCPSVQAPQVQREREPRGQG--RVALSLQLSDTDDNEA
FDELHIGSSDEKSHSDLSLTADTDRSMENLDILMGFGKSQLGSPD-EEEKQVPI---PLE
SRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGFVTVTRNEISINPAPI
GPKAEHTEILPQGMAHLQPGAA--ARDYTFLKRPEEETEKNIPKDDI-DNVTV------A
PTGSFSPRTVTQN-TQRPRPAKPTLTVSCQSNSRSSVSMGIYQKQSLTKIPARGKSSPQK
SKMI-EPELSSRVPSSGPVSLEKSPALAPGKLSRFKKTEGPAPLFD-LQPDSHIPKHPGQ
LPHGS-KMSSRKDWVQCSKSQIPASQLLPRPLNEPGDNGEPPTRDKHCDPGPE---AGMK
SPSP-PPPPDRSGSLLIRPSYDYLPPPSSAKPDTRVPNETARTIFKSPPLKGSSAPIISS
NQIM-TEVPGKKPSVAFKKPIFTHPLPS--TERVIQTRCSAHTPTSSFAVMAPGPLKVSP
KRG-VPRTPPHQTLGITQ--ADTGLRTPKNCPSAPEPLEISSPKSVSPGRKGQMNDC-VP
TS----------PKPAFLGANESPSSQGNSHSSS--PSSKSHNTPHGCQSAHEKGLKTRL
PVGFRVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVSKAKPEDAGNPVSMETTVG-
ER--TVTPLCFQAQGSLAEGLPLETAMPESLDNSILGADGKDGGESRAVKRSLSS-NKPH
LKPALGMNGAKARSQSFSAHSGDKPPTPP-MEGPGKVRTQIITNTAERGNSLTRQSS--S
AEVSPNKTPSAPMS--DSLPSVGRPLGHLSTRQGSLGSAGSSPSSQHGSPSKLPLRVPPT
SEGLLAPCGMEDKQGYAEGGCPT--MAVPEEPNSDHYTCPP-A------------P----
-TDCPRAPQNLGRTERPHSFETSRTSKL-ETSGRCP-DTSTTRTGAVSPEAPLSPTIEEK
VMLCIQENVEKGQVQTKCPSVEAKPKP-GPSLASWFGFRRSRLPALSSKKMDVPKTKVEK
KDAKGLGFGNKQLKSERKKEKKKPELQCKMENELARN-TRL--AQSPDNSLQSKNNLKTP
QDIYDQTKFEPRSRPSP-VTCSTKDTFMTELLNRVDKKAAQQTESGSNNVSCRSVLKGSS
QGSCLTSSSTSTQGNHKKNIKTKADVEIPKSSLIKEAGG-DLQEDE-DVIAE-----PTF
QSHIIESNCLMRTLDSGIGTFPLPDSGNRSTGRYICHPDSPEDTEPILPLQPTLCASSSI
RAQTLEREVPSSAD-SHVSADNAIVHSTSDPIMTTRGMRPLESRLPKPASSGKINSQKQN
EAE-PRPQTCSSFEYAENTM--ATEQLPDWGCAAPT-AETQKLK----------------
------------------------------------------------------------
-----------------------------QVEETKEDPENRLSKISLE-SFNKYNSKTMI
LLEREKNSLNTVERQKEEKEKTEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------------------------------------------------------------
-------MGEMSLQQ----EYKRHREKLS---AERAASQHYGERQKHEKLIQELEEERHL
RLQSEKRLQEVTFESERNRAQMRGLQRQFSRMEETVRNLLQSQGSPQQNKEETVSIL-VY
QEKLSEEERKHKETLDDLH--TVVDEDSRSESSSTDEGKEKTRLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPSSDLLLQKQ------------------------------------QLN-AKSGTP---
TLRCPG-LGVVVPSRL-CPRNSCSSS--ELSLSSACSEYSSSSSYTWRD--GKNLGRRQP
SQNWDKRRSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVS--
LEPS-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPSCKPPGVGSLCQESHQTFAYE
ADSHEVTDDDSSSLALLQAVPNPGC---RLHGSKLTHSVSDSLFGWELNGKHFAGGTSS-
IYPRERPEKLTR-ANKGPLDRKLCPRVQVPLLQRDRDLHSQGRDAA-LIPQLSDTDDNET
LDELHIESSDEKSPSDLSLTADTDKSMENLDIHIGLEKSEHGSPD-EEEKQVPT---QLE
ARPKTFSFIKQQRVVKRTSSEECITVIFDSEDGEPFEFSSHQTGVLTVTRNKISISTTPA
GPTAEHTELLPQGIAHLYPGAT--AKDCVFLKRSEEETEKNIPTGGV-DSVSS------A
PTGPLSSRTVTQN-VK-QKLAKPTHSMSCHSTSRSVAPSSIYQKQNLTKIPARGKSSSQK
SKIT-EPEGSTLVPSSGPATLEKSPALLPGKLAQLMKTENIGSLCE-VPPDSHIPKLPRH
LSHGP-KMASRRDWAQCSKHQAPGS--RSRLLIEPGDSGEPPTRDKLCASGPE---AGMA
SASPPPPPPGRLVSLLVRPRHDCPSPPSSATPECRAPSDAARMVSKSSLLKGASAPIISS
NQAT-AEVQKKKPSMAFKKPVFPHVLPS--TETVIHPGCPAHASSSSFPMITPGLPKVSP
KKG-VPKTSPHQTLGTTH--VDTGLRVPKTCPSTHEPLETLTSKSMSPGRR-QLNDS-IH
AS----------PKPFFLGANESPSSQVSSSISS-SSSSKGHSTPHGCQNAREKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSC-VAPSRPKLEDSRNPANLEAT-GC
ER--NSLTPGLHTPDRLAEGLPLETVLPESLENGIPEADRRDGIENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKASPPA-VEGAGKIRTQIITNTAERGNSLTRHNT--S
TEGSPSNTHSAPAP--ESLLCA----GRSFSRQGSLGSTGST-SSQHGSPNKLPLRIPPK
TEGLQTQPGTEDQQIYMGEECTS--VALPEEPGSDPYRGPL-T------------P----
-KDCPRVPQAPGRTVRPSILETSRTSKP-EISGRHP-DVCTTRTGAVSPEAPLSPTIEEK
VMLCIQENVEKGQVQTKSTSVEAKPKP-GPSFASWFGFRKSRLPALSSRKMDFSKTKVER
KDVKVLGFGNKQLKSERKKEKKKPEPQCEIENELHRD-PTL--ADSPDSGLQSKTNMKLS
HDMYNQMNFGAENTPSP-VTCSTKDTFMTELLNRVDKKGTQQTENGSNNVSCRNVLKGSS
QGSCLTGSSISTQGSHKKNIKTKVDMEIARDSLVKESNE-NIQEDEEGTIAD-----SAF
LNHAIESNCQMRTLDSGIGTFPLPDSGNRVTGRYMCQPDPSEDTKPLLSVQQAPSAASSI
RAQTLEREVPSSTD-GRLAAETAIVHSTSDPIMVARGTQPPQSRLPKPASSGKISFQNQN
EAE-PRPQICSSLEYAAGTV--TGKPLPDWGSDGTA-AETQKLKQVEET-----------
------------------------------------------------------------
------------------------KEDPEH----------RLSKISLK-SFNKFNSNSVI
LLEK-ENSVSKVEGQKEEREKNEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------------------------------------------------------------
--MDSNKCIEHLLAQLREQHRSLWREKLAVARLQREVAQRTSQGAMQEKLIHELEEERQL
RLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKIT-AY
QERVSEEERKEQAALGDLRV--EADEDSRSEHSSTEGGKEDSRLLLKRLKALEAENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSILFQQRV
RPASDVLLQEH------------------------------------LQN-AKSGAP---
ALKHSG-SGVVIPDHP-CPRNSCSSGS-ELSLSSTCSEYSSGSSYTWQD--RKLNGKRQT
SQIWDKRLSIDSS----------LPSGFTSPADELPPTRIKESHILEGLRKLQKRKVL--
LESPASVMSKWGYKDCMNSNEGIYSPGIKN-S-SLKECPPCQSPGRGIPCQNLHQTFNYD
ANSHEYAHEEFLSSASPRTSPSQGC---RIQSSKLTHSVSDSLFTWEPHRKYFAEGTAS-
VYTREMPERLTRCASHCPLERKLCPSVHLPWVQRDRDPHSQGPGHVPLNLQLSDTDDNET
LHELHIESSDERSPSDLSLTGDTDRSMENLG--VKFGKSECVSHD-KGKEECPT---HLE
TSPKAFSFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEISISSTPA
GPSEELTELSPQGITHFQPGAT--ARDYPFLGRPEEEPKTNIPKDEN--GILT------A
PNDSFNSPTTVTQNSPRPKLVKPTQGVAWQSNSRSVANMSVYTKQGLTKIPSRSKISPQK
SKLV-DPMPTTLVPSSGLGTLAKTPASPTGKLSQCTNAESPGTFCD-VQPESHIPKHPTQ
LPHIP-KISNKKNWVQCPKSQTAGIQ--SRHLMGKSDNGESPTRAKRCGSEPK---TRMR
SPSP-PTPPGRSVSLLVRPSYDYPPLPSPAKPETKAPGDTVSTGLKSPVLKGSSAPLVSS
SPAM-SEIQK-KPSVASRKSAFPTALPS--TQAVVHTRYPEHTSSSPFAVTAPGPTKVSP
KRG-IPKAPHPQALGTTH--MDTDLQTPKTRPSSYELLEMTSCKNLSPGRKGQLSDS-TV
TP----------HRPSFSGPNEFLTPQVNSTSSS-SSSCRNQGTSQGGQNPPEKGPKTRL
PVGLRVLMKSPQLLRKTSMVPGKQEKDSLNEASRSS-VTANKSNPEDSKDPASLETS-RD
--ERTTALLGLRGPESLARGLGLESTPPESLESSISRDDGRDGVDSRAIKRSFSS-SKPH
LKPALGMNGAKARSQSFSFHLGEKPSTPP-IEGPGKIRTQIITNTAERGNSLTRQNI--S
MEGSPSKTPSVSTP--DNLPNAGRPLGNPFSRQGSLCSTGSS-SSQHGSPSKLPLRMLTR
PEGLLT-PEEEDQRFSTQEECPGRG--VHEQSSSNHHRHPS-S-----------TL----
-SDCPQSLQVPGRIQRPSNLETNGISKL-ETSGRHP-DASPTGTSVVSPEAPLSPSIEEK
VMLCIQENVEKGQAQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRMEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKRENELSR-GTKKADGQSPDDGLQNTESLKAT
QDIYNQMKSEPRNRPSP-AVSPTKDAFMTELLNRVDKRAALQTESGSKGVSCRSVLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVDE-DVREDEEDRVAD-----AAL
QSHVIESNCQMRTLDSGIGTFPLPDSGNRSMGRYICQQDSPEDTDPLLPLQPAPSMPSSA
RAQTLDREVPSSTD-SQSSSESTIIHSVSDPSMMARGIRASQSHLPKPTTSGKTSFEKQN
GAE-SKATTGPSFEYAEDAV--PSEPLSGWRGEDAT-TENQVVVIPH-------------
------------------------------------------------------------
------------------------PESPVE----------RKSHD---------------
------------------------------------------------------------
-

------------------------------------------------------------
--MDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFHQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWETNRKHILEGTSS-
VYPRERPEKLTSCASSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKSVENLDVLVGFGKSLCGSPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHAELLPQGITCLQPGAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKPVKPTHTLSCQSNSRSSAPMGIYHKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSLASVPGKLSRFVKTESSGPLFE-LRPDPHIPKHPTQ
LPH---RLPSRRDWVHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHGGSGPE---AGVK
SPSP-PPPPGRSVSLLARPSYDYAPAPSSTKSETRVLSETARTPFKSPLLKGISAPVISS
NQAT-TEVQRKKPSVAFKKPVFTCPTPS--PEAVIHTRCPAHAPSSSFTVMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-SSPSKSHHSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASMEITA-G
ER--NVTTPDSQAQDSLAEGLPLETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPA-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLPLRVPPK
SEGLLIPPGKENQQAFTQGECPS--VAILAEPGSDRHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEARQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKALGFGNRQLKSERKKEKKKPELQCETENELVKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSTNASCRNVLKGGS
QVSCLTGSSLSTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SVF
QSHIIESSCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALSAVSSM
RAQTLEREVPSSTA-SQRPADSTIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANQPLPDWGGEDAA-TRTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFHSNTVI
LLEKEKNSLNKVEGQKEEKEKNEETSLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

---------------------------------M-------------------------Q
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEDTVNIM-VY
QEKLSEEERKHKEALEDLH--MMVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LGLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNTYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SLITKWGYKDCMNSNEGIYSPGIK-SS-SVKEYPPCKAADLGSPCKEPHKTFVYD
LDSHDDAGDD-STLALLQAVPNQSY---RPHARKLTHSVSDSQFGWEMNRKHFLEGTTS-
VYPRERPEKLTSCASSCPLESKLCPSVQAPQVQR--EPQGQGHSRVALHLQLSDTDDNET
LDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLFESPD-EEEKQVPI---ASE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGLVTVTRNEISINSAPT
GPKAEHTELLPQGIACLQPGAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPK------V
STESFSSRTVTQN-SQQQKLVKPMHTVSCQSNSRSSAPVGIYQKQNLTKIPARGKSSPQK
SKLM-EAEATALLPSSGLVTLEKPPALAPGKLTRFMKTETPGPLFE-LRPDPHIPKHPAQ
LPHSS-RMPSRRDWVQYPKSQTPGSR--SRPDIDSNDSGEPPTRDEHCGSGLE---AGAK
SPSP-PPPPGRSISLLSRPSCDYSLAPSSTKSETRLPSEIARTSFKSPLLKGTSAPVISS
NQAT-TEVQRKKPSVAFKKPVFTHPMPS--PEAVIQTRCPAHAPSSPFTVMALGLPKVSP
KRG-VPKTSPRQTLGAPQ--MDAGLQTSRNSPSTHEPLEITPSKSVSPVRKGQLNDR-AS
TS----------PKPSYLGVNESPSSQVSSPSSL-SSPSKSHNSSHGCQSAHEKGLKTRL
PVGLKVLIKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPGDSKSPASVA-ATAG
ER--NVTILDSQVQDSLAEKLPLETALQESLESSIPGSDGRDGIDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSTPP-MEGPGKIRTQIITNTAERGNSLTRQNS--S
TESSPNKIASAPMS--ESLPSAGKPLGHPSSRQGSLGSSSSS-TSQHGSPSKLPLRVPPK
AEGLLNPLEKEDQQAYAQGECPS--VAVLGEPDGDCHRCPP-T------------Q----
-TGFPEALQSPGRTQHPNTFETSSISKL-ETSGRHP-DASATVTDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNKQLKPERKKEKKKPELPCEIENELIKD-PKS--ADNPVGGLQSKSNRKTP
QDIYNQLKFEPRKRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLTSSSINTQGNHKKNMKIKADMEVSEDSLIKEGNE-NLQEDEEDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTERYLCQPDSPEDTEPLLPLQPAFSAASSM
RAQTLEREVPSSTD-GQRPADSVIVHSASDPIMTARGMQPLQSRLPKPASSGKGSTQKPN
EAE-PRPQTCSSFGYAEDPM--ASQLLPDWGSEDAA-SGTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFNSNTVI
LLEKEKNSLNKVEGRKEEKEKNEETSLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------MEGKR-QL----EKRDS-GKRLSLDSSL-------------------------M
EYMDSNKCIEHLLTQLREQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLREVTLESECNRIQMRSLQQRFSRMEETVRSLLQSQGCPEQKKEETVKIT-VY
QERLSEEERKHQEALGSPH--MVVDEDSRSRSSCSDEGKDKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPVSDLLLQVTEVDEDLREDEEDIVPDSALPS--------HIIESNCQMRTLDSGIG---
TFPLPD-SGTRSTGRYICQSESPEDTEPLLPLQPAPSTASSARAQT--------LE-REV
PSSADNQCSSESSIIHSISDPGMMTRGMQAPQSLLPKPT---------------------
------------------------SSGIETS-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTLHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWERNRKHFLEGTSS-
VYPRERPEKLTSCSSSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESGDEKSPSDASLAADTEKSVENLDILVGFGKSLCGSPD-EEEEQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRKEISINSAPT
GPKAEHTELLPQGITCLQPEAA--ARDSTFFKRSEEDMEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTHTLSYQSNSRSSAPMGIYQKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSPASVPGKLSRFMKTDSSGPLFE-LRPDPHIPKHPTQ
LPHSS-RLPSRRDWVHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGTK
SPSP-PPPPGRSVSLLARPSYDYSPAPSSTRSETRVLSETARTPFKSPLLKGISAPVISS
NQVV-TEVQRKKPSVAFKKPVFTYPTPS--PEAVIQTQCPAHAPSSSFTIMALGPPKVSP
KRG-ALKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-PSPSKSHHSPHGCQNAHEKGLKTRL
PVGLKVLMKSPQQLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKTPASMEITA-G
ER--NVTIPDSQAQDSLAEGLPPETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPP-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLLLRVPPK
SEGLLIPPGKENQQAFTQGECPS--VAILAEPSSDRHRCPP-T------------P----
-TECPEVLQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFTSWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELLKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLTGSSISTQGNHKKNMKGKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SAF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALPAVSSV
RAQTLEREVPSSTD-SQRPADSAIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANKPLPDWGGEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

ME------GKR-QLD----KRDF-GKRLSLDSSL-------------------------V
DYMDSNKCIEHLLTQLRQQHRSLWREKLAVARLQREVAQKTNQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMRGLQQQFSRMEETVRSLLQSQGSPEHKREEPSKIT-AY
EERVSEEERKHQEALADLQV--VVDEDSRSENSSTDEGKENTRLLLKRLKALEAENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRV
RPASDVLLREH------------------------------------LQN-AKSGTP---
ALKHSG-LGGVIPDHL-CPRNSCSS-S-ELSLSSTCSEYSSGSSYTWHD--QKLIGKRQS
SQNWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGTKN-S-SLKEYPPCQPPGIGIPCKDLHHSFIYD
ANSHENADEDSPPSALLQAAPSLSC---RMQGSKLTHSVSDSLFSWEPHGKYFSEGTVS-
VYTREMPERLVRCASHCPLERKLRPSMHLPWVQRDRDPSSQGHGYVALTLPLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDKSMENLD--VGSGKSECSSRD-VEEEECLT---HLE
TRPKTFGFIRQQRVVKRTSSEECVTVVFDAENGEPVEFSSHQTGVVTVTRDEISINSAPA
EPS-ELTQLSPQGITHLQPGAI--ARDCPFQKRPEEETEKNIPKDES--SIPI------A
LTDSVGPRTIVTQNSPRPKLTKPTQGVAWQSNSRPGANMGVYAHQGLTKIPSRGKSTPQK
SKLV-EPVPAMLLPSSGLVTLEKTPASPPGKLPQCKKTESPDSLCD-VKPESHIPKHPTQ
LPHVT-KISNKKNWVQCPKSQAPGIQ--S-HLMGSGNHGESPMKAKHCGSGSE---TRVR
SPSP-PPPPGRSVSLLVRPIYDYPPLLSPAKPETRVPRDTVSPVVKSPPLKGASVPVISP
SPAT-SEVQKKKISVASKKPTFPPAPPP--TDAVVHT------SSSSFDVMAPGPPKVSP
KRG-IPRPHPHQALGTTH--MDTELQTPKTYPSNQELLEVASSKSLSPGRKGQLSDS-SM
IL----------HRPSISGTNESLTSQVNSPSPS-SSSCRSQGTSQSRQNPPEKGPKTRL
PVGLKVLMMSPQLLRKTSVVPGKQEKDSLNEASRSS-VTSNKSNPEDSRDPASLEAS-GD
--ERKTALLGPRDLDSVAGGLPLESALPESLESSISKADGRDGMENRWVKRSFSS-SKPH
LKPALGMNGAKARSQSFSLHLGEKPSTPP-TEGPGKIRTQIITNTAERGNSLTRHNI--S
MEGSPSKSSCVSTS--DKLPNVGRPVEQTFSRQSSLCSTGSS-GSQHGSPSKLPLRMLTR
PEELTT-PGVEDQ----QEECPGMDV-VHEQSSSDHHRHPS-T------------P----
-SDCAESLQIPGRMQHPSNLETSGIYEL-ETSGCHP-EASPTGHGIMSPEAPLSPSIEEK
VMLCIQENVEKGQAQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRTEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKIESELNR-GTRVADGQSSDDGVRGTHNLKAS
QDIYNEMKLEPRNKPSP-AVCTTKDAFMMELLNRVDKKAALQTESGSKGVSCRSVLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNE-DLREDEEDRLAD-----SAL
QSHVLESNCQMRTLDSGIGTFPLPDSGNRSMGRYICQPDSPEDTEPLPPLQPASSITSSA
RAQTLEREVPSSTD-SQSSSESTVIHSISDPSVMARGIQALQSHLPKATSSGKTSFQKQN
EAE-SKTQTGPSFEYVEDAV--AREPLSGWRGEDAA-TETQELKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISPE-SFNKFNGNTVI
LLET-EKSPSKVKGQKEEKGKNIDASSSNSARPGGDNNVESLSDSLYDSFSSCASQGSNE
A

------------------------------------------------------------
--MDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAVHEKLIHELEEERHL
RLQSEKRLREVTLESECNRAQMRGLQRQFSRMEETVRNLLQSQGPPEQNKEETVNML-VY
QEKLSEEERKHKEALDTLH--MVVDEDSRSESSSTDEGREKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQ------------------------------------EPQLN-AKSGTP---
ALRCPG-LGLVVPSHL-CPRNSYS-SS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQP
SQNWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVL--
LEPS-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPSCKPPGVGSPCQESHKTFVYD
AASHEGANDDPSSLALLQAVPNLGC---RLHGSKLTHSVSDSLFFWELNGKHFSGGTSS-
VYPRERPEKLTH-ASNCPLERKLCPWVRVPLVQQDRDPHSQGHDHTALTLQLSDMDDNET
LDELHIESSDDKSTSELSLTADTDKSTENLDVLMGFEKSEHGSPD-E-EKQVPT---QSE
TRPKTFSFMKQQRVVKRTSSEECITVIFDAEDSEPLEFSSHQTGVAAVTRNEISIHTAPA
GPTAEHTELLPQGITHLHPGAA--PRDCPFLKRSEEETEKNIPTGGV-DCVSS------A
PTDPFSSRTVTQN-APQQKLTKPIPSMSCHRNSSSVAPMGVYQKQNLTKIPARGKSSPQK
SKVT-ESEGSTLIPSCGPVTLKKSPALPPGKLARLMKTESTGPLGD-VRPDSHIPTLPTQ
PSRGP-RMSSRRDWAQCPKSQTPGSR--SRLLIEACDSGEPPTRDKYCASGPEVTPAGVT
SPSP-PPPPGRSVSLL-RSHYDSALPPASATPESRLPSDTGRAVCKSPLLKGASAPVTSH
Q-AT-TEVQKKKPSIAFKKPIFPHVLPS--AEAVIHPGCPAHAPSSSFAVMTPRAPKVSP
KRG-VPKTSPHQTLGTTH--MDTGLRVPKTCPSTHESLEIPPSKSVSPGK-RQVNDS-VH
AS----------PKPFFLGANESPSSQVSSSTSS-ASSSKSHSTPNGCQNAREKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAASRPKLEDSRNPANLEA-AGC
KG--NSPTLGLHTADRLAEGLPLETVLPEALGNGTPAADGRDRIENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSPPT-VEGPGKIRTQIITNTAERGNSLTRQNT--S
MEGSPSHTGSTPTS--ESLLC----AGHPFSRQGSLGSTGST-NSQHGSPSKLPLRVSPK
SEGLHTQPGTEDPQVYIGGECVS--VALPEESGSDHCRCPP-T------------P----
-TDCPLVPQAPGRSLRPNSLETSRTSKL-EISGRHP-DVSTTRTGAISPEAPLSPTIEEK
VMLCIQENVEKGQVQTKSTSVEAKPKP-GPSFASWFGFRKSRLPALSSRKMDFSKAKVER
KDVKVLGFGNKQLKSERKKEKKKSELQCVTENELNRS-TRL--ADTPDSGLQSKSNLKPS
QDMCNHMNFEPRNRPNP-VTCSTKDTFMVELLNRVDKKGTQQMEGGSNNVSCRNVLKGSS
QGSCLTGSSISTQGSHKKNIKTKVDMEISRDSLVKEANE-NLQEDGEDTIAD-----SAF
QSHVVESNCQMRTLDSGIGTFPLPDSGNRVTGRYTCQPDCSEDTEPLLSLQQAPSIASSI
RAHTLDQEVPSSTD-SQLATETATVHSASEPIMMARVTRPPQCHLPKPASSGKTSFQKQN
EAE-LRPQTCSSFEYAEDTA--AGKPLPDWGSDDPA-PETQKLK----------------
------------------------------------------------------------
-----------------------------QVEETKEDPENRLSKISLE-SFNKFNSNSVI
LLEK-ENSLSKVGGQKEERERNEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MNSNEGIYSPGVK-CG-SHHEQTHCKPMEIGSSCIEHNKTFSYD
SDSHDDADDDSSSLLLLQEVPSKDC---RIYCNKLTHSVSDSLFHWDPNRKHLPERSSY-
FNSKERPEKLTSFVSGFQAEVESCTRTKLPDLQLDQSHAN--IGWKDLNFQLSDTDDNEV
LDELHIESSDEKSPSDLLATPFTEKYTKNSDVLIVTENSQFISSD-KEERQTSA---HSD
IRPKTCNFIKQQKVIKKTSSEECITVIFDAEDGEPIEFSSHQIGVVTVTRNEISVNQPES
RSSAEYTELIPQGIANLQAGTN--ARDYSVLEGPEDKTKKQTLEDNTGNKNMV---VTTT
CSESSPCGRIILQNAPRQKLVKPVYDVSYKTNSSSIVHAGVNQKPILTKIPSRGKFSPQK
NKMT-ESEEAPVATSVTPATLEKSPALPPVKLSRLKKAQSPPRNFD-SKVDFQVPKPPAH
PLPSS-KRPSRGNGTKYPKSQSPASPLLPQHLIEPTDYGEPPTRDSNHDLAT----VEAR
SPSP-PLPPGRSTSLLIRPDYAHSQPA-AVKLGGAVPGETAKNILKPSPLKGTANSGIHN
-QSS-HDMQAKSLSSGA-KIELSYLQEN--SEAIMQNKCISQQPHSA----CQGLSKVST
KQV-CLKNTNQMGLHRNREFLSMDSQTGRSIPLGPS-LET-TSQEVHSSKKDISSDSGVD
QPQKMPNILPATPQCHTASVSEPLLSQVNNSPLS--TLFHGSDTANATQNSNEKGVKTRL
PVGLKLFVKSPQLLRKSSTVPGKQEKDSINAASKSH-VSTSKHKQN--ERVATKG---AI
DAELKDSKSDTEIKDNFSLRLSVDTASPRSHENGSLVVDRVDELESKLVKRSFSSSNKSH
LKPALGMNGAKARSQSFSVHTGEKSSTLV-TEGLGKVRTQIITNTSDRGNSLTRQNS--A
MEGLQIKAIPGSGATQETLSNTSKNTENAYSRQGSLGSNS---NNQHGSPSKLPFRSSPK
VDLFRNTSKYDGNKSFSMKDARS--LSVQSEKSSENLKHEALNKKSVLPAELELDTSATV
SSKQISSIHSLGGIKCPHKLEAIKSQRQ-QMSLKLA-E-APQ-VTDVFSSPALQPTIEEK
VMLCIQENVQKGQEQNKSPTVETKQKT-GPSIASWFGFRKSKLPALSSRKPDVPKTKVEK
KEPRVSGFGIKQSKLERRKEKKQTEQHCEVENEINRK-TDS--SDFLDDAME-FKILKPS
RNTSGKIGCEQLRGSSI-ATYSSKDSFMKELLNR-------------------SVSKGSS
QGSSLHSNSISSQGNHKKNSNTKADMEIQNQTLANVVAE-NLQEEEEDTMTR-----TTC
QSHVIGTTLYFTL-DF--IAVSVPGGKKN-V-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERNRSLTQSR-TDAEVHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTLALLQAVPKQSC---RPHGSKLTHSVSDSLFGWETNRKHFLEGTSS-
VYPKERPEKLTSCASSCPLEMKLCPSVQMPQVQRERGPQGQGHGRMALNLQLSDTDDNET
LDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLCESPE-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPA
GPKAEHTELLPQGIACLQPRAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTHNISCQSNYRSSAPMGIYQKQNLTKIPARGKSSPQK
SKLM-EPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTERSGPLFE-LRPDPHIPKHPAQ
LPHSS-RMPSRRDWVQCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGAK
SPSP-PPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGTSAPVISS
NPAT-TEVQRKKPSVAFKKPIFTHPMPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-VPKTSPRQTLGTPQ--MDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGVNESPSSQVSSSSSS-SSPSKSHNSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASME-ITAG
ER--NVTLLDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSTPP-MEGSGKVRTQIITNTAERGNSLTRQNS--S
TESSPNKAPSAPML--ESLPSVGRPSGHPSSRQGSLGSSGSF-SSQHGSPSKLPLRIPPK
SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDHRRCPP-P------------P----
-TDCPEALQSPGRTQHLSTFETSSTSKL-ETSGRHP-DASATATDAMSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDISKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKD-TKS--ADNPDGGLQSKNNQRTP
QDIYNQLKIEPRNRHSP-VACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRSVLKGSS
QGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANE-NLQEDEDDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSM
RAQTLEREVPSSTD-HQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQN
EAE-PRPQTCSSFGYAEDPM--ASQPLPDWGSEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQHQFSRMEETVRNLLQSQGPPEQKKEDTVNIM-VY
QETLSEEERKHKEALEDLH--MVVDEDSRSESSSADEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRI-LDLSSGDLLSEVERSRSLTQSR-TDVELHEYQLN-AKSGTP---
ALKCPG-LGVVVPGHL-CPRNSCS-SS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTDELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SAITKWGYKDCMNSNEGIYSPGIK-SS-SLKECSPCKPTDTASPRKKPHKAFVFD
TDSHDDADDSSSSLVLLQATPSQSC---RPHGSKLTHSVSDSLFGWEPDGRHFSEGTSS-
VYPSERLEKLPSCASACPLERNLCPSVQPPHAQRGRDPHRQGHGRMALSLQLSDTDDNET
VGELHIESSDEKSPSDLSLAADTNKSLENLDVLMAFGKSQPESPD-EEEKQVPI---HVE
TRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGVITVTRNEISINSAPT
GPKAEHTELLPQGITCLQPGAA--ARDCPFFKRSEEETERHIPKANV-DTVPM------V
PTESFSPRTVTPN-TQQQKLVRPTHSMSCQSSSRSLASLGVYQKQSLTKIPARGKSSPQK
SKLM-EPEASTLVPSSGPVTVEKSPALAPGKLSRFTKTESPGPLFE-LRPDSHIPKLPTQ
LPHSS-RMPSRRDWVQCSTSHTPGSR--SRPLIAPSDGGEPPTRDGHCNSGPE---AGAR
SPSP-PPPPGRSVSLQARPSHECSPPPSTAKPEPRVPGETARTLFKSPLLKGASTPATSS
NQAT-AEVQRKKPSVAFRKPIFTHALPS--PDTVVPTRCPAHAPSSSFAAMALGPPKVSP
KRG-VPKTSPHQTLGTTQ--MDTGLRTPRNGPLTHEPLEISSSKSVSPGRKGQWNDS-VP
AP----------PRPSFLGASESPSSQVSSASSS-SSSSKSHSTPHGCQSAREKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVSKSKPEDSRSPASPDETPGG
GK--RVTAAGLPVQDGSAEGLPLEAALPESLEGSIPGADGRDGAENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPP-VEGPGKVRTQIITNTAERGNSLTRQNS--S
TEASPSKTPSALVS--ESLPGAGRPSGLPSSSQGSLGSSGSC-SSHHGSPSKLPLRIPPK
SEGLLIPPGEGAQQAYAQGECLH--VAVPVEPASDRCRCPP-T------------P----
-TDCPQALQSPGRMQCPSYFETSRTSKL-ETSGRHP-DASTTGTGALSSEAPPSPTIEEK
VMLCIQENVEKGQVQTKSTSVEAKQKP-GPSFASWFGFRKSRLPALSGRKMDVSKTKVEK
KDAKVLGFGNKQLKSERKKEKKKPEVQREIESEVIRD-TTS--ADSPDGGLQSKNNWKTP
QDIYNQMKFEPRNRPSP-VTCSSKDTFLTELLNRVDKKTAQQTESGSNNVSCRNVLKGSS
QASCLTGNSISTQGNHKKNIKAKADMEIPKDSLIKEANE-NLQEDEEDTVAD-----SAF
QSHSIESNCQMRTLDSGIGTFPLPDSGNRSAGRYLCQPDFPEDAEPPLPVQPALSAASPI
RAQTLEREVPSSAD-GQRPADSAIVHSASDPLMTARGVRPLQSRLPKPASSGKISSQKQN
EAE-PRPQTCTSFEYAEDPM--ASEPLTDWGGEDAA-TETQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKEDPENRLSKISLE-SFNKFNSNTVI
LLEK-ENSLNKVEGHKEEKEKNEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHKSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGPPEQRKEETVNIM-VY
QENLSEEERKHKEALEDLH--LMVDEDSRSESSSADEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRI-LGLSSGDLLSEVERSRSLTQSR-TDVELHEHQLN-TKSGAP---
ALKCPG-LGIIVPSHL-CPRNSCSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTDELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKDSRSCKPTDLGSPRKESHKTFVYD
TDSHDDADDDSSSLALLQVAANQGC---RSRGSKLTHSVSDSLFGWELNRNHFLEGTSS-
VYPRERPEKLTSCASSCPLERKLCPSVQTPQVLRERVPHSQGHGHVALSLQLSDTDDNET
LDELHIESGDEKSPSDLSLTADTDKSVENLDILMGFGKSQLRSPD-EEEKQVPI---HLE
TRPKTFNFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISVNSAPP
GPKAEHTELLPQGIAYLQPGAA--AKDCTFLKRSEEETEKNIPKDNV-DNVPM------A
PAESFSPRTVTQN-TQPQKLLKPTHGMSCQSNSRSLAPMGIYQKQSLTKIPAKGKSSPQK
SKLM-EPEVSTLVPSYGPMALEKSPALAPGKLSRFTKTENPGPLFE-LRPDSHIPKHPTQ
LPQGS-KMSGRRDWVQCSKSQTPGTQ--SKPLIEPSDSGEPPTRDEDCDSGLE---TGMK
SPSP-PPPPGRSVSLLSRPSCDYSPTPSPLKPETRVPSETVRAIFKSPLLKGTST-VLSS
HQIT-TEVQRKKPSVAFKKPVFTHPLPS--SETVIQTRCPAHAPSSSFAVMALGPPRVSP
KRG-VPKTSPHQTLGTTQ--MDTGLRTPKNCPSTHEPLEISSSKSISPGRKGQLNDS-VS
TP----------PIPPFLGVNESPSSQVNSPPAS-SPPCKSHSTPHGCQSAHEKGLKTRL
PVGLRVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VSASKPKPEDPRNPASLA-TSGC
ER--NGTPLVLQVQDSSAEGFPLEIALPESLDSSIPGADGRDGVENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSIHSGDKPSTPP-MEGPGKVRTQIITNTAERGNSLTRQNS--S
LESSPNKAPSAPMS--ESLPSAGRPLAHPSSRQGSLGSSGSS-SSQHGSPSKLPLRIPLK
SEGLLTPPGKENQQIYTQGECPS--VALPAESDSECCRCPP-T------------P----
-TDSPQALQSPGRMQHPSSSETSRMSKL-ETSGRHP-DASTTGTGAASSEAPFSPTIEEK
VMLCIQENVEKGQVQTKSTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDASKAKVEK
KDAKVLGFGSKPLKSERKKEKKKPELQCEIENELIRD-TQS--ADIQDSGFQSKNNRKTT
QDIYNQMKCEPRNRPSP-VTCSTKDTFMTELLNRVDKKASQQTESGSNDVSCRNVLKGSS
QGSCLTGSSINIQGNHKKSVKTKADMEIPKDSLIKEANE-NLQEDEEDTVAD-----SAF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYICQPDSSEDTEPLLSLQPALSTASSI
RAQTLEREVPSSAD-SQRPAGSTIVHSTSDPIMTARGMRPLQSHLPKPASSGKISSPKQN
EAE-PRPQTCSSFKYAEDPM--ASEPLPDWGGEDAA-AETQDKV----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGS--DSNCDYGDNRFGARRGQ
LVRALNSATPEIETT---------------------------------------------
-

--------------------MPM-VKRCCL---------------CLCLWCNAALFFYVQ
EYMDSNKYIEHLLNQLEEQHRSLWREKLAVARLQREVAQRRNEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGPPEQKKEETVNIM-VY
QEKLSEEERKHKAALEGRH--MVLDEDSRSEGSSADEGKGKTKWLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDL-LQKLHSRI-LDLSSGDLLSDVERSQSLTHSR-TDVEMHGCQLN-TKAGTP---
ALKCPG-MGVAVSGHL-CPRSSYSSS--ELSLSSTCSEYSSGSSYTWHD--GKNLRKR-S
SQNWDKRLSIDSS----------LPSGFASPTDELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKPTDTGSPSTDPHKAFVYD
MDSHDEADEDASSLASVQVVPNQVC---RLHSCKLTHSVSDSLFGWELNGKHCSEITSS-
VYSRERPEKLTGCASNCPLEQKLCPGVQGPRVQREKVSPIQG--CQTLSLQPSDTDDTET
LDELHIDSSDEKSPSDMSATADTDQSTENLDILTGFEKSSRGSPE-EEENQVPI---HLE
SRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGLVTVTRKEISIHQAPA
GPQMEHTELSPQGIAHSQPGPA--ARDYPFLKRSEEETERNIPQDEV-DDTAM------A
PAVSFHPRTVTQN---TQRLAKPMRVTPCQSHSRSAVGTGICQKKSLTKIPTRGKSSPQK
SKVR-EPEASLIMPSAGPVTLEKSP--APAKLSQFKKTEGPAPLFD-LQPDSHIPKPPTQ
LPHGS-KMSSRRDWVQSSKSQILASQLLSRPPTERSDDGEPPTRDKHCDPGPE---AGVK
SPSP-PSPPGRSVSLLIRPSYDFLPPPSSAKSESRVPNETARMVLKSPPLKGSSAPVIYF
NQTL-TDVQGKKPSVAFRKPVFTPSPPS--AETAIQMRSPAHSPSSSFAVMVPENPKVSP
KRN-VPRAPPHQTLGTTQ--NNTGLQTPKNYASPREPLEILSSKGVSPRRKEQLNGS-VS
AS----------SKPSFLGVNESPSSQVNSPSSS--ASFKSHNPLHGCQNLHERGLKTRL
PVGLKVFIKSPQLLRKSSTVPGKQEKDSLNEASKTS-VAVSKAKPGAFRNPASLQTTGG-
--EINASPVGLPAQESLAEGLPLERAMPESLEDSMPGADRKDGVENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGEKPPTPP-TEGLGKVRTQIITNTAERGNSLTRQSS--S
TEGSPSKSASAPMS--DGLPSTGRPLGHPSPRQGSLGSTGSS-SSQHGSPSKLPLKIPPK
SEELLTPAGTEEQQAYAQGEGPR--VTVPEEPGSDHCRCPL-T------------P----
-TDSSGGPQSLGRTPHPSSFTASRTSKL-ETSGRYT-DTSTTRAGVVSPEAPLSPTIEEK
VMLCIQENVEKGQVQTKSTTVEIKPKP-GPSFASWFGFRRSRLPALSSRKMDVSKTKAEK
KDAKGLGFGNKQLKSERKKEKKKPELQCEMENELHRD-IEL--ADGPDSGLQNRNNLKTP
PDIYDQVKFESRNRPSP-VPCSAKDIFMTELLNRVDKKAAQQAESGSNNLSCRSVLKGSP
QGSCLTSSSLSTQGNHKKNIKTKADMEKPKGSPIREANE-HLQEDEEDTVAD-----SAF
QSHTIETNCQMRTLDSGIGTFPLPDSGTRAAGRYIRQADSPEDTDPILSLQLALCAASSM
RAQTLEREVPSSAD-SQGSADNAIVHSTSDPIMTARGMRPLQNLLPKPASSGKIGSQMQN
EAE-PRSQNCSSFEYVENTM--ASKPLPAWEGDGAA-AETQKLKQVEET-----------
------------------------------------------------------------
------------------------REDPENRLCKISLESFNKYDSNTVI---LLGKEKNS
LNKI--------EGQKEEKEKTEEASLSSSDRPG-IDHLESLSDSLYDSFSSCASQGSND
V

MQLQLSLVSRRTKPFRRERECTFAVGSLKGKHSL-------------------------F
IYL--------ILWFFFFLFTQNCLEKLAVARLQREVAQRTSQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKIT-AY
QEGLTEEERKEQAALGDLHV-VAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENAALA
LENEHQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRV
RPASDVLLQEH------------------------------------LQN-AKSGTP---
ALKHSG-SGVVIPDHL-CPRNSCSSGS-ELSLSSTCSEYSSGSSYTWQD--RKLIGKRQS
SRIWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQNRKVF--
LESPSLVISKWGYKDCMNSNEGIYSPGIKT-S-SLKECPPCQPSGMGIPCQNLHQTFIYD
ANSHEDAHEEFPSSALPLTSPSQGY---RVQGSKLAHSLSDSLFNWEPHRKYFAEGTAS-
VYTREMPERLARCASHCPLERKLCPSIHLPWVQRDRDPHSQVHGHVPLNLQLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDKSMENLE--VGFRKSEGGSRD-MGEEACPT---HLE
TSPKAFSFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEISISSALA
GPSEELTELSPQEITHFQAGAT--ARDCPFLKRPEEETAKNIPKDEN--RILT------A
PNDSFSSQTIITQNSPRPKLAKPTQGVAWQSNSRPVGNMGVYTKQGLTKIPSRGKSSPQK
SKLV-ESMPTMLVLSSALVTPEKTPASPMGKLSQCRKAESPGSLCD-VQPESHIPKHPAQ
LPHIP-KISNKKNWVQCPRSQTSGIQ--SRHLMGRSDSSESPMRSNGCVSDPQ---TRMR
SPSP-PTPPGRSVSLLVRPSYDYPPLPSPAKPETQVPGDAVSPGLKSPLLKGSSAPLVSS
SPVM-SEIQK-KPSVASRKSAFPPALPS--TQAVVHTRYPEHIPSSPFAVTTSGPPKVSP
KRG-IPKPPPHYALGTAH--MDTDLQTPKTCPSSCELLEVTSCKSLSPGRKRQLSDS-TV
MP----------HRPSFSGVNESLTPQVNSPSSS-SSSCRNQGSSQGGPNSPEKGPKTRL
PVGLKVLMKSPQLLRKTSLVPGKQEKDSLNEASRSS-VAANTSNPEDSKDPASLETS-RD
--ERTTALLGVRGPDSLARGLALDSTMPESLECSISRDDGRDGADNRAIKRSFSS-SKPH
LKPALGMNGAKARSQSFSIHLGEKPSTPP-TEGPGKIRTQIITNTAERGNSLTRQNI--S
MEGSPSKTPSVSTS--DNLPNAGRPLGNPFSRQSSLCSTGSS-SSQHGSPSKLPLRMLTR
PEGLLT-PGVEDQRFSTQKECPERG--VHEQSSSDHHRHPS-------------PL----
-SDCPQFQHVPGRMQRPSNLETSGISKL-ETSGRHP-DASSTGTSVVSPEAPLSPSIEEK
VMLCIQENVEKGQVQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRMEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKIENELSR-GTKKADGQSPDDGLQSSESLKAS
QDIYNQMKSEPRNRPSP-AVCPTKDAFMTELLNRVDKRASVQTESGSKGVSCRSLLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNE-DVQEDEEDRVAD-----TTL
QSHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASVASSA
RAQTLDREVPSSTD-SQSSPESMIIHSISDPSMMARELRASQSHLPKPTSSGKPSFEKQN
GAE-SKAHTGPSFEYAEDAV--ASEPLSGWRGEDAT-TETQEPKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISLE-SFNKFSSNTVI
LLGK-EKSPSEVEGQKEEKGKKTEVSSSSSERPG-VDRVESLSDSLYDSFSSCASQASNE
A

ME------GKR-QLD----KRDF-GKRLSLDSSL-------------------------V
EYMDSNKCIEHLLTQLREQHRSLWREKLAVARLQREVAQRTNQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMRGLQQQFS------------------------------
-ERVSEEERKHQEALADLHA--VVDEDSRSENSSTDEGKENTRLLLKRLKALEAENSALA
LENENQREQYERCLDE-------------DLREECVKLKTRVFDLEQQNRALSILFQQRV
RPASDVLLREH------------------------------------LQN-ANSGTP---
ALKHSG-SGGVIPDHL-CPRNSCSS-S-ELSLSSACSEYSSSSSYTWQD--QKLTGKRQS
SQNWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVIAKWGYKDCMNSNEGIYSPGIKN-S-SLKEYPHSQPPGIGIPCKDLHHSLIYD
ANSHENADEDSPPSALLQVAPSPGC---RRQGSKLAHSVSDSLFNWEPQGKYISEGTAS-
VYTREMPERLVRCSSHCPLERKLCPSMHLPWVQRDRDPSSQDHSYVALNLQLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDKSMENLD--MGSGKFECCSHD-VE-EKCLT---HSE
TRPKTLGFIRQQRVVKRTSSEECVMVVFDAENGEPVEFSSRQTGVVTVTRDEISINSAPA
EPS-ELTQLSPQGITHLQPGAT--ARDCPFQKRPEEETEKNIPKDES--SIPI------A
LTDSFGPRIVVTQNSPRPKLTKPTQGVAWQSNSRPGTNMGVYAQQGLTKIPSRGNSSPQK
AKLA-EPVPAMLVPSSGLETLEKTPASPPGKLPQGKKTESPGSLCD-VQPESHIPKHPTQ
LLHVT-KIPSKKNWVQCPKAQAPGIQ--SQHLMRSSGNGESPMKAKCCSSGPE---TRVR
SPSP-PPPPGRSASLLVRPSNDYAPLPSPANPETRVSRDTVSAGVKSPPLKGASVPVISS
RSAM-SEMQKKKPSVAPKKPSFPPAPPP--TDAAVHT------SSSSFAVMVPGPPKVSP
KRG-IPKPHPHQALGATH--KDTDLQTPKTCPSNQELLEVASSKSLSPGRKGQLSDN-SM
IP----------HRPSLSGTNESLTPQVNSLSPS-PSSCRSQGTSQSRQNPPEKGPKTRL
PVGLKVLMKSPQLLRKMSMVPGKQEKDSLNEASRSC-VTSNKPNPEDYRDPASLEAS-GD
--ARTTVLLGPRDLDSLARELPLEPTLPESLESSISKADARDGMESRWVKRSFSS-SKPH
LKPALGMNGAKARSQSFSIHLGEKSSTPP-TEGPGKIRTQIITNTAERGNSLTRHNI--S
MEGSPSKRPGVSTS--DNLPNAGRPVEQTFSRQSSLCSTGSS-SSQHGSPSKLPLRVLTR
PEELTT-PGVEDQQSYTQEEWPGLDV-AHEQCGSDHHRHPS-T------------P----
-SDCPQSLQIPGRVQCVSNLETSGICEL-ETSGCHP-EASPTGPGIMSPGAPLSPSIEEK
VMLCIQENVEKGQAQTKATSVEVKPRA-GPSFTSWFGFRKSRLPALSSRRTEASKSKAEK
KDPK--------LKSERKREKKKAEVQSKTESELNR-DTRVADGRSSDDGLRGTRNLKES
QDLYNEMKLEPRNKPSPAAVCSTKDAFMTELLNRVDKKAALQTESGSKGVSCRSMLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNE-DLREDEEDRVAD-----SAL
QSHVLESSCQMRTLDSGIGTFPLPDSGTRSMGRYIHQPDSPEDTEPLPPLQPASSITSSA
RAQTLEREVPSSTD-SQSSSGSTVIHSISDPSMMARGIQALQSHLPKPTSSGKTSFQKQK
EAE-SKTQTGPSFEYAEDAV--AHEPLSGWRGEDAA-TETQ-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------METPRDSLIKEANE-NLPEDEEDTIAD-----SSF
QSHIIESNCQMRTLDSGIGTFPLPDSANRSTGRYTCQPESSEDSEPLLSLQPTS---SHV
RAQTLEREVPSSTV-SQHSAEITIVHSTSDPIMTARGIRPPQSRLPKPASSGKTYFQKES
EVA-SSPQTCSSFKYAEELR--ANEPSPDWEREDAS-TETQ-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------------------------------------------------------------
--MDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEDTVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSADEGKEKTRLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LKPP-SLITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKAADPGSPCKEPHKTFVYD
LDSHDDADDDSSTLALLQAVPNQSY---RPHGSKLTHSVSDSLFGWEMNRKHFLEGTPS-
VYPRERPEKLTSCASSCPLERKLCPSVQPPRVQR--EPQGQGHSHVALHLQLSDTDDNET
LDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLFESPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHTELLPQGIACLQPGAA--ARDYTFLKRSEEDTEKNIPKDNV-DNVPR------V
STEAFSSRTATQN-SQQQKLVKPTHTVSCQSNSRSSAPVGIYQKQNLTKIPARGKSSPQK
SKLM-EPEATALLPSSGLVTLEKPPALAPGKLTRFMKTETPGPLFE-LRPDPHIPKHPTQ
LPHSS-RMPSRRDWVQCPKSQTPGSP--SRPDIESNDSGEPPTRDEHCDSGLE---AETK
SPSP-PPPPGRSVSLLARPSCDYSPASSSTKSETRLPSEIARTPFKSPLLKGTSALVISS
NQAT-TEVQRKKPSVAFKKPVFTHPMPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-VPKTSPRQTLGTPQ--MDAGLQTPRNSPSTHEPLEITSSKSVSPVRKGQLNDR-AS
TS----------PKPSFLGVNESPSSQVSSPSSS-SSPSKSHNSSHGCQSAHEKGLKTRL
PVGLKVLIKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPGASKNPASVE-TTAG
ER--NVTIPDSQAQDSLADGLPLETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSTPP-MEGPGKVRTQIITNTAERGNSLTRQNS--S
AESSPNKVPCAPMS--ESLPSAGRPLGHPSSRQGSLGSSGSS-TSQHGSPSKLPLRVPPK
AEGLLTPLGKEDQQAYAQEECPS--VGVLGEPDGDCHRCPP-T------------P----
-TGFPEALQSPGRTQHPSTFETSSISKL-ETSGRHP-DASATVTDAVSSEAPLSPTIEEK
VMLCIQENVEKGQAQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNKQLKSERKKEKKKPELQCEIENELIKD-PKS--ADNPVSGLQSKSNRKT-
QDIYSQLKFEPRKRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSSNASCRSVLKGSS
QGSCLTGSSINTQGNHKKNMKIKADMEVSEDSLIKEGNE-NLQEDEEDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDTEPLLPLQSAFSAASSM
RAQTLEREVPSSTD-GQRPADSAIVHSASDPIMTARGMRPLQSRLPKPASSGKGSTQKQN
EAE-PRPQTCSAFGYAEDPM--ASQLLPDWGSEDAA-SGTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFNSNTVI
LLEKEKNSLNKVEGRKEEKEKNEETSLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------------------------------------------------------------
--MDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQKTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MMVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWETNRKHVLEGTSS-
VYPRERPEKLTSCASSCPLERKLCPSVQTPQVQRERGPHGQGRGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKSVENLDVLVGFGKSLCGSPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHAELLPQGITCLQPGAA--ARDYTFFKRSEEDTEKNIPKDNA-DNVPR------V
SPESFSSRTVTQN-PQQQKPIKPTHTLSCQSNSRSSAPMGICHKQNLTKIPARGKSSPQK
SKRM-EPEASTLLPSSGLVTLEKSPASVPGKLSRFVKTESSGPPFE-LRPDPHIPKHPTQ
LPH---RLPSRRDWVHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGLE---AGLK
SPSP-PPPPGRSVSLLARPSYDYAPAPSSTKSETRVLSETARTPFKSPLLKGISAPVISS
NQAA-TEVQRKKPSVSFKKPVFTYPTPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-SSPSKSHHSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSENPASMEITA-G
ER--NVNTPDSQAQDSLAEGLPPETALQESLESSIPGSDGRDGVDTRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPA-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGPPSSRQGSLGSSGSS-SSQHGSPSKLPLRVPPK
SEGLLIPPGKENQQAFTQGECPS--VAILAEPGSDRHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSRL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPEPQCETENELVKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSTNASCGNVLKGSS
QGSCLTGSSLSTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALSAVSSM
RAQTLEREVPSSTA-SQRPADSTIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAADPM--ANQPLPDWGGEDAA-TGTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFHSNTVI
LLEKEKNSLNKVEGQEEEKEKNEETSLSSSDRPG-VDNLETLSDSLYDSFSSCASQGSND
V

------------------------------------------------------------
------------------------------------------------MCILKKVLDKFL
KLRTK-----------------EREEKIYFLMEETVRNLLQSQGPPEQNKEETVSVL-VY
QEKLSEEERKHKEALDDLP--TVVDEDSRSESSSTDEGKEKNKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQES------------------------------------QLN-AKSGTP---
ALRCPG-LGLVLPGHL-CPRNSCSSS--ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQP
SQNWDKRLSIDSS----------LPCDFASPADELPPTRIKESHILEGLRRLQKRKVL--
LEPS-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPSCKPPGVGSPCHESHKTFVYD
TASQEDADDDSSSLALLQTVPNLGC---RLHGSKLTHSVSDSLFCWELNGKHFSGATSS-
FYPRERPEKLTP-SSNCPLDRKLCPRVQMPLLQRDRDPHIQGHDNTALNLQLSDMDDNET
FDELHIESSDDKSPSELSLTADTDKSMENLDILMGSEKSEHGSPN-EKEKQVPI---QLE
SRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPFEFSSYQTGVATVMRNEISINTAPA
GPTAEHTELVPQGIAHLHPGAA--PKDCLFLKRSEEETEKNIPAGSI-DGISS------A
PTDPFISKTVTQN-VPQQKLAKL-TPMSYHSNSSSVAPMGIYQRQNLTKIPARGKSSPQK
SKIL-KSEGCTLIPSSSPVTLEKSPALPPGKLARFMKSESTGPLGD-VKPDSHIPKLPTQ
PSHGP-RMSSRRDWTECSKNQTPRSR--STLLIEPGDSGEPPTRDKHCVSGPE---AGVT
SPSP-PPTPGRSVSLLLRPPYESPSPPVSTKPETRPPSDTMKTVLKSSPLKGASAPLTPN
Q-AT-AEMQ-KKKPVTFKKPVFPHVLPS--TETMIHPRCPAHAPSSSFAMLSPGAPKVSP
KRS-VPKTSPHQTLGTTH--MDTGLRVPKTCPSTHEPLEIQPSMNASPGRK-QVNDG-VH
TS----------PKPFFLGASESPSSQVSSSTSS-SSSSKSRSAPHGCQNAHEKGLKTRL
PVGLKVLMKSPQLLRKNSTVPGKHEKDSLNEASKSF-VAASRPKLEDSRNPANLGAT-GC
E--RNSPTPGSHTPDRLAEGLPLETMLLKSLENGIPGADRRDGTENRSVKRSLSS-IKPH
LKPALGMNGAKARSQSFSSHSGDKPSPPS-VEGPGKIRTQIITNTAERGNSLTRQNT--S
IEGSLNNSNPTPTS--ESLFC----AGHPFSKQGSLGSADST-SSHHGSPSKLPLRISPK
SEGLQTQCGTKDQQVHIGGECAS--VAVPEESDSDHCWYPL-T------------P----
-TDSPQVPQAAGRTLHQSSLETIRTSKL-ETSGRHP-DISAAKTAAVSPEAPLSPTIEEK
VMLCIQENVEKGQVQTKSPSVEAKPKP-GPSFASWFGFRKSRLPALSSRKMDFSKTK KS-
------------------------------------------------------------
-----------------------------FPIY RVDKKGTQQTESGSNSVSCRNALKGSS
QGSCLTGSSIGTQGSHKKNIKTKMDMEISRDSLVKEANE-NIQEDEEDTIAD-----SAF
QSHVVESNCQMRTLDSGIGTFPLPDSGNRVTARYLCQPDSSEDTEPLLPLQQAPSTACSI
RAQTLEREVPSFTD-SQLATEMAIVHSTSDPIMMARGTRPPQSHLPKAASSGKTSFQKQS
EAE-LRPQMCSSFEYAEDTV--AGKLLPDWGRDDTV-AKTQKLK----------------
------------------------------------------------------------
-----------------------------QVEETKEDPENRLSKISLE-SFNKFNSNTVI
LLEK-ETSLSKVEGQKEEREKNEEASFSSSERPG-VDNLESLSDSLYDSFSSCASQGSND
V

------MEGKR-QL----EKRDF-GKRLSLDSSLVDADGEGENPASQINFLNSISMIRIH
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRRSEGAMHEKLMHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGPSEQKKEETVNIM-VY
QEKLSEEERKHKETLEGLH--MVVDEDSRSESSSADEGKENTKFLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRI
RPTSDLLLQKLHSRI-LDLSSGDLLSDVERSRSLTQSR-TDVEMHECQLT-AKSGAP---
ALKCPG-LGVVIPGHL-CPRNSCS-SS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRKS
SQNWDKRLSIDSS----------LPSGFSSPTDELPPTRIKESHILEGLRKLQKRRVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SN-SLKEYRPCKPADTRSPCKEPHEAFVYD
TDSHDDADEDSSSLALLQAAPSQSC---RLHSRKLTHSVSDSLFGWELNRKHFSEGMSS-
VYPRERPKKLTSCASNCPLERKLYPSVQPPQVQREREPRGLD--RVALSLQFSDTDDNEA
LNELHIGSSDEKSPSDLSLTADTDKSMENLDI-MGFGKSQLGSPD-EEEKQVPI---PLE
SRPKTFSFIKQQRVVKRTSSEECITVIFDAEDGEPIEFSSHQTGMVTVTRNEISINQAPT
GPKAEHTELLPQGIGHLPTAAA--ARDYTFLKRPEEEMEKNIPKDDV-DKVAV------V
PSGSFSPRTVTQS-TQQQRPAKSTLNLSCQSNSRSSVSMGIYQKQSLTKIPARGKSSPQK
SKIM-EPEATLRIPSSDPVSLEKSPALAPGKLSRFKKTESPAPLFD-LRPDPHIPKHPSQ
LPHGP-KLSSRKDWAPCSKSQIPPLQLLPRPLIEPSDDIGSPMRDKHRDSVLE---AGVK
SPSP-PPPPDRAGSLLIQPSYDYLPPPSSAKPETRVPSETARTILKSPPLKGSSAPIISS
NPVMAGEVLGKKSSVAFRKPVFTHPLPS--TETVTQTRCSAHPPSSSFAMMAPGPPKVSP
KRDQKPKTPPHQTLGTTQ--TDTGLRTPKNCPSTHEPLEILSSKSVSPGRKGQLNDC-VP
TS----------PKPSLLEVNESPSSQVNSHSSP--PPTKSHNSPHGCQNTHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVSRSKPQDSGNPVSPETTA-D
ER--NGTPLSFQAQDGLAEGLPLETAMPESLEHSIPGADGKDGLENRSVKRSLSS-NKPH
LKPALGMNGAKARSQSFSAHPGDKPPTPP-LEGPGKVRTQIITNTAERGNSLTRQSS--S
TEGSPNKTPCAPMSTSDSVLGAGRPPGHPSPRQGSLGSAGSS-GGQHGSPSRLPLRVPPK
PQELLAPCGTEAEQGYGQGRHAG--VAVPEEPSSDPSRCPP-T------------P----
-TDCPRAPQDTGRTQRPNNFETSRTSKL-ETSGRCP-DTSTTRTGTVSPEALVSPTIEEK
VMLCIQENVERGQVQTKPPSVEAKPKP-GPSFASWFGFRRSRLPALSSRKMDVSKTKVEK
KDAKGLGFGNKQLKSEKKKEKKKPEPQCKIENELTRN-AKL--AEGPDNSLQNKNNLKAP
QDMYDQMKLEPRNRPSP-VACSTKDTFMTELLNRVDKKAAQQTESGSNNVSCRSVLKGSS
QGSCLTGSSASTQGNHKKNIKTKADGEIPKGSLIKEASE-NLQEDE-DTIAD-----STF
QSHIIESNCLMRTLDSGIGTFPLPDSGNRSTGRYICHPDSPEDTEPILSLQPALCAASSI
RAQTLEREVPSSAD-SHASADNTIVHSTSDPIMTARGMRPLESRLPKPASSGKINSQKQN
EAE---PQTCSSFEYAENTI--TSEQLPEWGSEDPT-AETQDKV----------------
------------------------------------------------------------
-----------------------------PRMCAYSASGGSDSDSDLDYGNNGFGAGRGK
LVKAMKSATQEIETS---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRSLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERNRSLTQSR-TDAEVHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHVDADDDPSTLALLQAVPNQSC---RPHGSKLTHSVSDSLFGWETNRKHFLEGTSS-
VYPKERPEKLTSCASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNET
FDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGFGKSLCGSPE-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPA
GPKAEHTELLPQGIACLQPRAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPPRGKSSPQK
SKLM-EPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFE-LRSDPHIPKHSAQ
LPHSS-RMPSRRDWVQCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGVK
SPSP-PPPPGRSVSLLARPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGISAPVISS
NPAT-TEVQRKKPSVAFKKPIFTHPMPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-VPKTSPRQTLGTPQ--RDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGVNESPSSQVSSSSSS-SSPAKSHNSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASME-ITAG
ER--NVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSS-SKPH
LKPALGMNGAKARSHSFSTHSGDKPSTPP-IEGSGKVRTQIITNTAERGNSLTRQNS--S
TESSPNKAPSAPML--ESLPSVGRPSGHPSSGKGSLGSSGSF-SSQHGSPSKLPLRIPPK
SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRSCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDISKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKD-TKS--ADNPDGGLQSKNNRRTP
QDIYNQLKIEPRNRHSP-VACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANE-NLQEDEDDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSM
RAQTLEREVPSSTD-GQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQN
EAE-PRPQTCSSFGYAEDPM--ASQPLPDWGSEVAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDLDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEAVEDLH--MVVNEDARSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
KPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTLALLQAVPNQSC---RPHGSKLTHSVSDSLFGWETNRKHFLEGTSS-
VYPRERPEKLTSCASSCPLEMKLCPSVQTPQVQRERGPHGQGHGRMALNLQLSDTDDNET
LDELHIESSDEKSPSDVSLAADTDKSVENLDVFVGFGKSLCGSPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHTELLPQGIACLQPRAA--ARDYTFFKRSEEDPEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTHAISCQSNSRSSAPMGIYRKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSPALAPGKLSRFTKTESSGPLFE-LRPDPHIPKHPAQ
LLHSS-RMPSRRDWVQCPKNQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGAK
SPSP-PPPPGRSVSLLARPSCDYSPAPSSTKSETRVPSETARTPFKSPLLKGTSAPVIYS
NPAM-TEVQRKKSSAAFKKPIFTHPMPS--PEAVIQTRCSAHAPSSSFTVMALGPPKVSP
KRG-IPKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKRSFLGVNESPSSQVSSSSSS-SSPSKSHNSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASMD-ITAG
ER--NVTISDSQAQDSLADGLPLETALQESLESSIPGSDRRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSTHSGDKPSTPP-MEGPGKVRTQIITNTAERGNSLTRQNS--S
TESSPNKAPSAPVL--ESLPSAGRPLGHPSSRQGSLGISGSF-SSQHGSPSKLPLRIPPK
SEGLLIPPGKEDQQAFTPGECPNANMAILAEPGSDCHRCPP-T------------P----
-TDCPEAPQSPGRTQYPSTFETSSTSKL-ETSGGHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRRSRLPALSSRKMDISKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKD-TKS--ADNPDGGLQSKNNRRTP
QDIYNQLKIEPRNRHSP-VACSMKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLIGSSISSQGNHKKNMKIKADMEVPKDSLVKEANE-NLQEDEDDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSM
RAQTLEREVPSSTD-GQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQN
EAE-PRPQTCSSFGYAEDPM--ASQPLPDWGGEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDLDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

MQLQLSLVSRRTKPFRWERECTFAEGSLKGKHSL-------------------------F
I----------IYLFIYYFFTQNCLEKLAVARLQREVAQRTSQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKIA-AY
QERLAEEERKEQAALGDIHV-AEADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRV
RPASDVLLQEH------------------------------------LQN-AKSGTP---
ALKHSG-SGVVIPDHL-CPRNSCSSSS-ELSLSSTCSEYSSGSSYTWQD--RKLIGKRQS
SRIWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVF--
LESPSSVISKWGYKDCMNSNEGIYSPGIKT-S-SLKECPPCQPSGMGIPCQKLHQTFIYD
ANSHEDAHEDFPSSALPLTSPSQGY---RIQGSKLTHSVSDSLFNWEPHRKYFAEGTAS-
VYTREMPERLARCASHCPLERKLCPSIHLPWVQRDRDPHSQAHGHVPLNLQLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDKSMENLE--VGFRKSEGGSRD-MGEEACPT---HLE
TSPKAFGFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEIAISSALA
GPSEEVTELSPQEITHLQAGAA--ARDYPFLKKPEEETEKNIPKDEN--SLLT------A
PNDSFSSQTVITQNSPRPKLAKPTQGVAWQGNSRPVRNMGVYTKQGLTKIPSRGKSSPQK
SKLV-ESMPTMLVPSSALVTSEKTPASPMGKLSQCRKAESPGSLCD-VQPESHIPKHPTQ
LPHIP-KISNKKNCVQCPKNQTAGIQ--TLHLMGRSDSGESPMKPNGCVSEPQ---TRMR
SPSP-PTPPGRSVSLLVRPSYDYPPLPSPAKPETRVPGDTVSPGLTSPLLKGSAAPLVSS
GPVM-SEIQK-KPSVASRKPAFPPTPPS--TQAVVHTRYPEHIPSSPFAVTTSGPPKVSP
KRG-TPKLSPHHALGTAH--TDTDLQIPKTCPSSCELLEVTSCTSLSPGRKRQLSDS-TV
MP----------HRPSFSGVNESLTPQVNSPPSS-SSSCRNQGTSQGGQNPPEKGPKTRL
PVGLKVLMKSPQLLRKTSMVPGKQEKDSLNEASRSS-AAANKSNPEDSKDPTSLETS-RD
--ERTTALRGLRGPDSLARGLALDSTMTESLECSISRDDGRDGADSRAIKRSFSS-SKPH
LKPALGMNGAKARSQSFSSHLGEKPSTPP-TEGPGKIRTQIITNTAERGNSLTRQNI--S
MEGSPSKTPSVSTS--DNLPSAGRPLGNPFSRQSSLCSTGSS-SSQHGSPSKLPLRMLTR
PEGLLT-PGVDDQWFSTQEECPERG--VHEHSSSDHHRHPS-------------PL----
-SDCPQSQQVPGKMQCPSNLETSGISKL-ETSGRHP-DASSTGASVVSPEAPLSPSIEEK
VMLCIQENVEKGQVQTKSASVEVRPRA-GPSFTSWFGFRKSRLPALSSRRMEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKIENELSR-GTKKADGQSPDDGLQSSESLKHS
QDIYNQMKSEPRNRPSP-AVCPTKDAFMTELLNRVDKRATVQTESGSKGVSCRSVLEGTS
RGSCFASGSVSAQGSQKKNIKTKVDMENPRESLGAEVNE-DVREDEEDRVAD-----TPL
QSHMIESNCQMRTLDSGIGTFPLPDSGNRSTGRYTCQQDSPEDPDALLPLQPAPSMASSA
TAQTLDRKVPSSTD-SQSSPESMIIHSMSDPSMLAIEMRASQSHLPKPPSSGKPSFEKQN
GAE-SKAHTGPSFEYTEDAV--ASEPLSGWRGEDAT-TETQEPKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISLE-SFNKFSSNTVI
LLGK-EKSPSEVEGQKEEKDKKTEVSSSSSERPG-VDRVESLSDSLYDSFSSCASQASNE
A

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFHQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWETNRKHILEGTSS-
VYPRERPEKLTSCASSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKSVENLDVLVGFGKSLCGSPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGAVTVTRNEISINSAPT
GPKAEHAELLPQGITCLQPGAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKPVKPTHTLSCQSNSRSSAPMGIYHKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSLASVPGKLSRFVKTESSGPLFE-LRPDAHIPKHPTQ
LPH---RLPSRRDWVHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHGGSGPE---AGVK
SPSP-PPPPGRSVSLLARPSYDYAPAPSSTKSETRVLSETARTPFKSPLLKGISAPVISS
NQAT-TEVQRKKPSVAFKKPVFTCPTPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-SSPSKSHHSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASMEITA-G
ER--NVTTPDSQAQDSLAEGLPLETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPA-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLPLRVPPK
SEGLLIPPGKENQQAFTQGECPS--VAILAEPGSDRHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEARQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKALGFGNRQLKSERKKEKKKPELQCETENELVKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSTNASCRNVLKGGS
QVSCLTGSSLSTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SVF
QSHIIESSCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALSAVSSM
RAQTLEREVPSSTA-SQRPADSTIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANQPLPDWGGEDAA-TRTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MG-TSWNAGPTPVPE-----EKL
GALTRETNCQMRTLDSGIGTFPLPDSGNRSTGRYMCQPDSPEDAESLLPLQPALFAASSV
KAQTLEREVPSSAD-SQSSAENTIVHSTSDPIVTARRMLPLQSRLPKPASSGKMPME--N
EAE-PGPQTCSSFEYAENTT--VSGPLPAWGADSAA-AETQVRRG---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGPPEQKKEDTVNIM-VY
QEKLSEEERKHKEALEDLH--MMVDEDSRSESSSADEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRI-LNLSSGDLLSEVERSRSVTQSR-TDVELHEYQLN-AKSGTL---
ALKCPG-LGVVVPGHL-CPRNSCS-SS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTDELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKECSPCKPTDTGSPHKKPHKAFVFD
TDSHDDADDSSSSLVLLQATPSQGC---RPHGSKLTHSVSDSLFGWEPDGKHFSEGTSS-
VYPNERLEKLTSCASTRLLERNLCPSVQAPQVQRERDPHSQGHGRMALSLQLSDTDDNET
LGELHIESSDEKSPSDLSLAADTNKSLENLDVLMGFGKSQLESPD-EEEKQVPI---HVE
TRPKTFSFIKQQRVIKRTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHTELLPQGITCLQPGAD--ARDCPFFKRSEEETEKHIPKATV-DTVPM------V
PTESFSPRTVTQN-TQHQKLVRPTHSMSCQSSSRSSASMGIHQKQSLTKIPARSKPSPQK
SKLM-EPEASTLVPSSGPVTLEKSPALAPGKLSRFTKTESPGPLFE-LRPDSHIPKHPTQ
LPHSS-KMPSRRDWAQCSTSHTPGSR--SRPLIAPSDSGEPRTRDGHCDSGPE---AGVR
SPSP-PPPPGRSVSLLTRPNHEYSPPPSTAKPEPRVPGEIARTLFKSPLLKGTSTAVSSS
NQAT-TEVQRKKPSVAFRKPIFTHPLPS--TETVVQTRCPAHAPSGSFSVMALGPPKVSP
KRV-VPKTSPHQSLGTTQ--MDTGLRTPKNCPLTHEPLEIPSSKSVSPGRKGQWNDS-VS
TS----------PKPSFLGVNESPSSQVSSVSPS-SSSSKSHSSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVSKSKPEDSRNPASPDETTGG
GK--HVTTLGLPAQDSLAEGLPLEAALPESLESSILGADGRDEVENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPP-MEGPGKVRTQIITNTAERGNSLTRQNS--S
TEGSPSKNPATLGS--EGLPTAGRPLGHPSSSQGSLGSSGSS-SSHHGSPSKLPLRIPPK
SEGLLIPPGEGGQQAYAQGECPC--VVVTVEPASDRCRRPP-T------------P----
-TDCPQALQSPGRMQCPSYFETSRTSKL-ETSGRHP-DASTTGTGALSSEAPPSPTIEEK
VMLCIQENVEKGQVQTKSTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMEVSKTKVEK
KDAKVLGFGNKQLKSERKKEKKKPELQCEIENEVIRD-TTS--ADSPDSGLQSKNNWKTP
QDIYNQMKFEPRNRPSP-VTCSSKDTFLTELLNRVDKKTAQQTESGSNNVSCRNVLKGSS
QGSCLTGSSISTQGNHKKNIKTKADMEIPKDSLIKEANE-NLQEDEEDTVAD-----SAF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYMCQPDFPEDAEPLLPLQPAPSAAASI
RAQTLEREVPSSAD-SQRPADSTIVHSASDPVMTARGMQPLQSRLPKPASSGKISSQKQN
EAE-PRPQTCASFEYAEDPM--ASERLPAWGGEDAA-AETQDKV----------------
------------------------------------------------------------
-----------------------------PRMCAYSASDGSDSDSDLDCGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLREVTLESERNRVQMRGLQRQFSRMEETVRNLLQSQGPPEQKREEPVNIM-TY
QEKPSEEERKHKEALDDLH--MVVDEDSRSENSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRI-LDLSSGDLLSEVGRSRSLTQSR-TDVELHEYQLN-ARSGTS---
ALKCTG-LGAVIPGHL-CPRNSCS-SS-ELSLSSTCSEYSSGSSYTWHD--SKNLRKRQS
TQNWDKRLSIDSS----------LPSGFASSADELPPTRIKESHILEGLRKLQKCKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SD-SLKEYPSSKLPGVGSPGRELHKTFVYD
TDPQEDADEDSSSLALLQTVPNEGC---RLHSSKLTHSVSDSLFGWEPDGKHFSEDMSS-
VYPREKPEKLSHCASNYPLDRKLCPSVQVPQVQRERDPHNQGHGHVALNLQLSDTDDNET
LDELRIESSDEKSPSDLSLTADTDKSTENLDILIGFGKSELESPK-E-EKTVPT---YLE
TRPKTFGFIKQQRVVKRTSSEECVTVIFDAEDGEPVEFSSHQTGVVTVTRNEISINTASA
GPKAEHMELSPQGIAHLQPGAAA-ARDSAFLRRSEEGSEKNIPKDDV-DHVPL------V
TIDSFSPQSVTQN-APRQKPTKPAHNMSCQSNSRSGASVGIYQKQSLTKIPARGKSSPQK
SKII-EPEASTLGSPSGLVTLEKSSALLPGKLSRFMKTESPGPFCSDAQTESHIPKHPLQ
FPHGP-KMSSRKDSVQCSKSQAPGSR--SRPLAEPHENGDPPTRDQRCDSEPD---LGMK
SPSP-PPPPGRSVSLLVRSSYDCLPPPSSAKSEARVPSDTARTVFKAPLLKGTFAPVISS
NHAT-TEVQRKKPSVAFKKPVFTHAPPS--TEATIPTRCPAHIPTSSFAMMSPGPPKFSP
KRG-VPKTSPHQTLGTLH--TDTGLRTPKNCPSIHEPVEIA-SKSVSPGRKGQVNDS-VL
AS----------PKPSFLGASESPSSQVNSSS----SSFKSHSAPYGCHNAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVGESKPEDSRHPARLE-TAGN
RG--TTSTLGSQGPDSLVEGLPLETALPESLENGILRADGKDGVENRSVKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPP-MEGSGKIRTQIITNTAERGNSLTRQNA--S
AESSPPKSSSAPAS--ESPPSAGKPLGHSFSRQCSQGSTGSS-SSQHGSPSKLPLRIPPK
PEGIPTPPGMEHQRAYAQVECAG--LTVSGEPGSDHCRCLP-T------------P----
-ADFPQALMAPGRTQPPNNLETSRASTL-ETSGRHP-DASKTESGAVSPEAPLSPTIEEK
VMLCIQENVEKGQVQTKSTSVEAKPKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNKQLKSERKKEKKKSELQYEIENVLNRG-NTS--EDSPEAGLQSKNNLKTS
PDIYNRMKLEPRNRPNP-VTCSAKDNFMTELLNRVDKKGAQQTESGSKNVSCRNMLKGSS
QGSCLIGSSISTQGSHKKNVKTKADVVTPRDSLIKEANE-NLQEDEEDTIAD-----SAF
QSHNLESNCQMRTLDSGIGTFPLPESGNRSMGRYLCPPDSPEETNPLLSLQPAPSTASSI
RAQTLEREVPSSAD-SQCSTKTAIVHSISDPIMTARGLRP-QSRLPKPASSGRSSFQKQN
EAG-PTPQTCSSFKYAEDTM--AGQPLPGWGGEDAA-AETQKLK----------------
------------------------------------------------------------
-----------------------------QVEETKEDSENRLSKISLE-SFNKFNSNTVI
LLEK-ENSLNKVEGQKEEKEKNEEASLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

ME------GKR-QLY----KRDF-GKRLSLDSSL-------------------------V
EYMDSNKCIEHLLAQLREQHRSLWREKLAVARLQREVAQRTNQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMRGLQQQFSRMEETVRSLLQSQGSPEQKREEPAKIT-AF
QERVSEAERKHQEELADLHS--AVDEDSRSESSSTDEGKENTRLLLQRLKALEAENSALA
LENESQREQYERCLDEVANQVVRALLTQKDLREECIKLKTRVFDLEQQNRVLSILFQQRV
RPASDVLLQGA------------------------------------EVH-EDLREDEED
RVADST-LQSHAIE------SNCQM-R-TLD--SGIGT------FPLPDSGNRSMGRYTC
QQ--------------------------DSPEDPEPLPSLHPT-----------------
---P-SVAS-----------------STRA-Q-TLEHKVPCSIDSQSSSESTIVHSV---
------SD----PSMM--------P---RGTQSHLPKPTSS--------GAETSR-----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-

------MEGKRQ-LDRR----DFGK-RLSLDSSL-------------------------V
EYMDSNKCIEHLLAQLREQHRSLWREKLAVARLQREVAQRTSQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKIT-AY
QEGLPDEERKEQAALGDLHV-VAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRV
RPASDVLLQEH------------------------------------LQN-AKSGTP---
ALKHSG-SGVVIPDHL-CPRNSCSSGS-ELSLSSTCSEYSSGSSYTWQD--RKLIGKRQS
SRIWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVF--
LESPSLVISKWGYKDCMNSNEGIYSPGIKT-S-SLKECPPCQPSGMGIPCQNLHQTFIYD
ANSHEDAHEELPSSALPLTSPSQGY---RIQGSKLTHSVSDSLFNWEPHRKYFAEGTAS-
VYTREMPERLARCASHCPLERKLCPSIHLPWVQRDRDPHSQVHGHVPLNLQLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDKSMENLE--VGFRKSEGGSRD-MGEEACPT---HLE
TSPKAFSFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEISISSALA
GPSEELTELSPQEITHFQAGAT--ARDCPFLKRPEEETAKNIPKDEN--HILT------A
PNDFFSSQTIITQNSPRPKLAKPTQGVAWQSNSRPVGNMGVYTKQGLTKIPSRGKSSPQK
SKLV-ESMPTMLVPSSALVTPEKTPASPMGKLSQCRKAESPGSLCD-VQPESHIPKHPAQ
VPHIP-KISNKKNWVQCPRSQTSGIQ--SRHLMGRSDSS--EMRSNGCVSAPQ---TRMR
SPSP-PTPPGRSVSLLVRPSYDYPPLPSPAKPETQGPGDAVSPGLKSPLLKGSSAPLVSS
SPVM-SEIQK-KPSVASRKSAFPPALPS--TQAVVHTRYPEHIASSPFAVTTSGPPKVSP
KRG-IPKPPPHHALGTAH--MDTDLQTPKTCPSSCELLEVTSCKSLSPGRKRQLSDS-TV
MP----------HRPSFSGVNESLTPQVNSPSSS-SSSCRNQGSSQGGQNSPEKGPKTRL
PVGLKVLMKSPQLLKKTSLVPGKQEKDSLNEASRSC-VAANTSNPEDSKDPASLETS-RD
--ERTTALLGVRGPDSLARGLALDSTMPESLECSISRDDGRDGADSRAIKRSFSS-SKPH
LKPALGMNGAKARSQSFSIHLGEKPSTPP-TEGPGKIRTQIITNTAERGNSLTRQNI--S
MEGSPSKTPSVSTS--DNLPNAGRPLGNPFSRQSSLCSTGSS-SSQHGSPSKLPLRMLTR
PEGLLT-PGVEDQRLSTQEECPERG--VHEQSSSDHHRHPS-------------PL----
-SDCPQFLHVPGRMQRPSNLETSGISKL-ETSGRHP-DASSTGTSVVSPEAPLSPSIEEK
VMLCIQENVEKGQVQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRMEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKIENELSR-GTKKADGQSPDDGLQSSESLKVS
QDIYNQMKLEPRNRPSP-AVCPTKDAFMTELLNRVDKRASVQRESGSKGVSCRSVLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNE-DVQEDEEDRVAD-----TTL
QSHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASMASSA
RAQTLDREVPSSTD-SQSSPESMIIHSISDPSMMAREMRASQSHLPKPTSSGKPSFEKQN
GAE-SKAHTGPSFEYAEDAV--ASEPLSGWRGEDAT-TETQEPKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISLE-SFNKFSSNTVI
LLGK-EKSPSEVEGQKEEKGKKTEVSSSSSERPG-VDRVESLSDSLYDSFSSCASQASNE
A

------------------------------------------------------------
--MDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TNAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSN---RPHGSKLTHSVSDSLFGWETNSKHVLEGTSS-
VYPRERPEKLTSCTSSCPLERKLCPSVQMPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKSVENLDVLVGFGKSLCGSPD-EEEKQVPV---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHAELLPQGITCLHPGAA--ARDYTFFKRSEEDTEKNIPKDNA-DNVPR------V
STESFSSRTVTQN-PQQQKPVKPTHTLSCQSNSRSSAPMGIYHKQNLTKIPARGKSSPQK
SKRM-EPEASTLLPSSGLVTLEKSAASVPGKLSRFMKTESSGPLFE-LRPDPHIPKHPTQ
LPH---RLPSRRDWAHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGVK
SPSP-PPPPGRSVSLLARPSYDYAPAPSSTKSETRVLSETARTPFKSPLLKGISAPVISS
NQAA-TEVQRKKPSVAFKKPVFTYPTPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-SSPSKSHHSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASMEITA-G
ER--NVTTPDSQAQDSLAEGLPLETALQESLESSIPGSDGRDGVDTRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPA-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLPLRVPPK
SEGLLIPPGKENQPALSQGECPS--VAILAEPGSDRHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSRL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKA-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPEPQCETENELVKD-TKS--ADNPDGGLQSKNNRKTP
QDIYSQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSTNASCRNVLKGSS
QGSCLTGSSLSTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SVF
QSHIIESSCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALSAVSSM
RAQTLEREVPSSTD-SQRPADSAIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANQPLPDWGGEDAA-TGTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFHSNTVI
LLEKEKNSLNKVEGQKEEKEKNEETSLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------------------------------------------------------------
--MDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERNRSLTQSR-TDAEVHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIR-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDPSTLALLQAVPNQSC---RPHGSKLTHSVSDSLFAWETNRKHFLEGTSS-
VYPKERPEKLTSCASSCPLEMKLCPSVQTPQVQRERGPQGQGHGRMALNLQLSDTDDNET
FDELHIESSDEKSPSDVSLAADTDKSVENLDVLVGLGKSLCGSPK-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSTPT
GPKAEHTELLPQGIACLQPRAA--ARDYTFFKRSEEDTEKNIPKDNV-DNIPR------V
STESFSSRTVTQN-PQQQKLVKPTHNISCQSNSRSSAPMGIYQKQNLTKIPARGKSSPQK
SKLM-EPEATTLLPSSGLVTLEKSPALAPGKLSRFMKTESSGPLFE-LRPDPHIPKHPAQ
LPHSS-RMPSRRDWVQCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGAK
SPSP-PPPPGRSVSLLAKPSYDYSPAPSSTKSETRVPSETARTPFKSPLLKGTSAPVISS
NPAT-TEVQRKKPSVAFKKPIFTHPMPS--PEAVIQTRFPAHAPSSSFTVMALGPPKVSP
KRG-VPKTSPRQTLGTPQ--MDIGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGVNESPSSQVSSSSSS-SSPAKSHNSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASME-ITAG
ER--NVTLPDSQAQGSLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSS-SKPH
LKPALGMNGAKARSHSFSTHSGDKPSTPP-MEGSGKVRTQIITNTAERGNSLTRQNS--S
TESSPNKAPSAPML--ESLPSVGRPSGHPSSRQGSLGSSGSF-SSQHGSTSKLPLRIPPK
SEGLLIPPGKEDQQAFTQGECPSANVAVLGEPGSDRRRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDISKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELIKD-TKS--ADNPDGGLQSKNNRRTP
QDIYNQLKIEPRNRHSP-VACSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANE-NLQEDEDDAVAD-----SVF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLTLQSALSAVSSM
RAQTLEREVPSSTD-GQRPADSAIVHSTSDPIMTARGMRPLQSRLPKPASSGKVSSQKQN
EAE-PRPQTCSSSGYAEDPM--ASQPLPDWGSEDAA-TGTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFNSNTVI
LLEKEKNSLNKVEGQKEEKEKNEETSLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

MQLQLPLVSRRTKPFRRERECTFALGGLKGKHSL-------------------------F
IYL--------ILCF-FFLFTQNHLEKLAVARLQREVAQRTSQGAMHEKLIHELEEERHL
RLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEEPAKIT-AY
QEGLTEEERKEQAALGDLHV-VAADEDSRSEHSSVEERKEDSRLLLKRLKALEAENSALA
LENENQREQYERCLDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQRV
RPASDVLLQEH------------------------------------LQN-AKSGTP---
ALKHSG-SGVVIPDHL-CPRNSCSSGS-ELSLSSTCSEYSSGSSYTWQD--RKLIGKRQS
SRIWDKRLSIDSS----------LPSGFASPADELPPTRIKESHILEGLRKLQKRKVF--
LESPSSVISKWGYKDCMNSNEGIYSPGIKT-S-SLKECPPCQPSGMGIPCQNLHQKFIYD
ANSHEDAHEEFPSPALPLTSPSQGY---RIQGSKLTHSVSDSLFNWEPHRKYFAEGTAS-
VYTREMPERLARCASHCPLERKLCPSMHLPWVQRDRDPHSQVHGHVPRNLQLSDTDDNET
LNELHIESSDERSPSDLSLTGDTDRSMENLE--VGFRKSEGGSRD-MGEEACPT---HLE
TSSKAFSFIKQQRVVKRTSSEECVTVIFDAENGEPVEFSSHQAGVVTVTRDEISISSALA
GPSEELTELSPQEITHLKVGTT--ARDCPFLKRPEEETEKNIPKDEN--RILT------A
PNDSFSSQIIITQNSPRSKLAKPTQGVAWQSNSRPVGNMGVYTKQGLTKIPSRGKSSPQK
SKLV-ESMPTMMVPSSALVTPEKTPASPMGKLSQCRKAESPGSLCD-VQPESHIPKHPAQ
LPHIP-KISNKKNWVQCPRSQTAGIQ--SRHLMGRRDSSESPMRSNGCVSEPQ---TRMR
SPSP-PTPPGRSVSLLVRPSYDYPPLPSPAKPETQVPGDTVSPGLKSPLLKGSSAPLVSS
SPVM-SEIQK-KPSVASRKSAFPPALSS--TQAVVHTGYPEHIPSSPFAVMTSGPPKVSP
KRG-IPKPPPHHALGTAH--MDTDLQTPKTCPSSRELLEVTSCKSLSPGRKRQLSDS-TV
MP----------HRPSFSGVNESLTPQVNSPSPS-SSSCRNQGTSRGGQNSPEKGPKTRL
PVGLKVLMKSPQLLRKTSLVPGKQEKDSLNEASRSS-VAANTSNPEDSKDPASLETS-RD
--ERTTALLGVRGPDSLARGLALDSTMPEPLECSISRDDGRDGADSRAIKRSFSS-SKPH
PKPALGMNGAKARSQSFSIHLGEKPSTPP-TEGPGKIRTQIITNTAERGNSLTRQNI--S
MEGSPSKIPSVSTS--DNLPSAGRPLGNPFSRQSSLCSTGSS-SSQHGSPSKLPLRMLTR
PEGLLT-PGVEDQRFSTQQECPERG--VHEQSSSDHHRHPS-------------PL----
-SDCPQFLHVPGRMQRPSNLETSGISKL-ETSGRHP-DASSTGTSVVSPEAPLSPSIEEK
VMLCIQENVEKGQVQTKSASVEVKPRA-GPSFTSWFGFRKSRLPALSSRRMEASKSKVEK
KDTK--------LKSERKKEKKKAEVQSKIENELSR-GTKKADGQSPDDGLQSSESLKAS
QDIYNQMKSEPRNRPSP-AVCPTKDAFMTELLNRVDKRAAVQTESGSKGVSCRSVLEGTS
QGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNE-DVQEDEEDRVAD-----TTL
QSHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASMASSA
RAQTLDHEVPSSTD-SQSSPESMIIHSISDPSMMAREMRASQSHLPKPTSSGKPSFEKQN
GAE-SKAHTGPSFEYAEDAV--ASEPLSGWRGEDAT-TETQEPKQVEET-----------
------------------------------------------------------------
------------------------KEDPEN----------RLSEISLE-SFNKFSSNTVI
LLGK-EKSPSEVEGQKEEKGKKTEVSSSSSERPG-VDRVESLSDSLYDSFSSCASQASNE
T

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SN-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWETNRKHILEGTSS-
VYPRERPEKLTSCASSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKSVENLDVLVGFGKPLCGSPD-EEEKQVPT---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHAELLPQGITCLHPGAA--ARDYTFFKRSEEDTEKNIPKDNA-DNVPR------V
STESFSSRTVTQN-PQQQKPVKPTHTLSCQSNSRSSAPMGIYHKQNLTKISARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSPASVPGKLSRFVKTESSGPLFE-LRPDPHIPKHPTQ
LPH---RLPSRRDWVRCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGVK
SPSP-PPPPGRSVSLLARPSYDYAPAPSSTKSETRVLSETARTPFKSPLLKGISAPVISS
NQAA-TEVQRKKPSVAFKKPVFTYPTPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPCLS-SSPSKSHHSPHGCQSAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSENPASMEITA-G
ER--NVTTPDSQAQDSLAEGLPLETALQESLESSIPGSDGRDGEDTRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPA-MEGPGKVRTQIITNTAERGNSLTRRNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLPLRIPPK
CEGLLIPPGKENQPAFTQGECPN--VAILAEPGSDRHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSRL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFTSWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPEPQCETENELVKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSTNASCRNVLKGSS
QGSCLTGSSLSTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SVF
QSHIIESSCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALSAVSSM
RAQTLEREVPSSTD-SQRPADSAIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFRYAEDPM--ANQPLPDWGGEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDPDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTLHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWERNRKHFLEGTSS-
VYPRERPEKLTSCSSSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESGDEKSPSDASLAADTEKSVENLDILVGFGKSLCGSPD-EEEEQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRKEISINSAPT
GPKAEHTELLPQGITCLQPEAA--ARDSTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTHTLSYQSNSRSSAPMGIYQKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSPASVPGKLSRFMKTDSSGPLFE-LRPDLHIPKHPTQ
LPHSS-RLPSRRDWVHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHCGSGPE---AGTK
SPSP-PPPPGRSVSLLARPSYDYSPAPSSTRSETRVLSETARTPFKSPLLKGISAPVISS
NQVV-TEVQRKKPSVAFKKPVFTYPTPS--PEAVIQTRCPAHAPSSSFTIMALGPPKVSP
KRG-ALKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-PSPSKSHHSPHGCQNAHEKGLKTRL
PVGLKVLMKSPQLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKTPASMEITA-G
ER--NVTIPDSQAQDSLAEGLPPETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPP-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLLLRVPPK
SEGLLIPPGKENQQAFTQGECPS--VAILAEPSSDRHRCPP-T------------P----
-TECPEVLQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFTSWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELLKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSSNASCRNVLKGSS
QGSCLTGSSISTQGNHKKNMKGKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SAF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALPAVSSV
RAQTLEREVPSSTD-SQRPADSAIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANKPLPDWGGEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDPDYGDNGFGAGRGQ
LVKALKSAAPEIET----------------------------------------------
-

------------------------------------------------------------
--MDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAMHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFHQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SLKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFTLLQAVPNQSY---RPHGSKLTHSVSDSLFGWETNRKHILEGTSS-
VYPRERPEKLTSCASSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKPVENLDVLVGFGKSLCGSPD-EEEKQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTTNEISINSAPT
GPKAEHAELLPQGITRLQPGAA--ARDYTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKPVKPTHTLSCQSNSRSSAPMGIYHKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSDLVTLEKSLASVPGKLSRFVKTESSGPLFE-LRPDPHIPKHPTQ
LPH---RLPSRRDWVHCPKSQTPGSR--SRPAIESSDSGEPPTRDEHGGSGPE---AGVK
SPSP-PPPPGRSVSLLARPSYDYAPAPSSTKSETRVLSETARTPFKSPLLKGISAPVISS
NQAT-TEVQRKKPSVAFKKPVFTCPTPS--PEAVIQTRCPAHAPSSSFTVMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLHDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-SSPSKSHHSPHGCQSAHEKGLKTRL
PVGLKVLVKSPRPLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKNPASLEITA-G
ER--NVTTPDSQAQDSLAEGLPLETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGDKPSTPA-MEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLPLRVPPK
SEGLLIPPGKENQQVFTQGECPS--VAILAEPGSDRHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEARQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCETENELVKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-ITCSTKDTFMTELLNRVDKKAAPQTESGSTNASCRNVLKGGS
QVSCLTGSSLSTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SVF
QSHIIESSCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALSAVSSM
RAQTLEREVPSSTD-SQRPADSTIVHSTSDPIMTARGLRPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANQPLPDWGGEDAA-TRTQKLK----------------
------------------------------------------------------------
-----------------------------QLEETKDDPENRLSKISLE-SFNKFHSNTVI
LLEKEKNSLNKVEGQKEEKEKNEETSLSSSDRPG-VDNLESLSDSLYDSFSSCASQGSND
V

------MEGKR-QL----EKRDF-GKRLSLDSSL-------------------------V
EYMDSNKYIEHLLSQLEEQHRSLWREKLAVARLQREVAQRTSEGAVHEKLIHELEEERHL
RLQSEKRLQEVTLESERNRIQMRGLQQQFSRMEETVRNLLQSQGSPEQKKEETVNIM-VY
QEKLSEEERKHKEALEDLH--MVVDEDSRSESSSTDEGKEKTKLLLERLKALEAENSALA
LENENQREQYERCLDEVANQVVQALLTQKDLREECVKLKTRVFDLEQQNRTLSILFQQRV
RPTSDLLLQKLHSRL-LDLSSGDLLSEVERSRSLTQSR-TDAELHEHQLN-TK---S---
ALKCPG-LGAVIPGHL-CPRNSYSSSS-ELSLSSTCSEYSSGSSYTWHD--GKNLRKRQS
SQNWDKRLSIDSS----------LPSGFASPTNELPPTRIKESHILEGLRKLQKRKVL--
LEPP-SVITKWGYKDCMNSNEGIYSPGIK-SS-SFKEYPPCKTADLGSPCKEPHKTFVYD
LDSHDDADDDSSTFALLQAVPNQSY---RPHGSKLTHSVSDSLFGWETNRKHFLEGTSS-
FYPRERPEKLTSCSSSCPLERKLCPSVQTPQVQRERGPHGQGHGCVALNLQLSDTDDNET
LDELHIESSDEKSPSDMSLAADTEKSVENLDILVGFGKSLCGSPD-EEEEQVPI---PSE
TRPKTFSFIKQQRVVKRTSSEECVTVIFDAEDGEPIEFSSHQTGVVTVTRNEISINSAPT
GPKAEHTELLPQGITCFQPGAA--ARDSTFFKRSEEDTEKNIPKDNV-DNVPR------V
STESFSSRTVTQN-PQQQKLVKPTRTLSCQSNSRSSAPMAIYQKQNLTKIPARGKSSPQK
SKLM-EPEASTLLPSSGLVTLEKSPASVPGKLSRFMKTESPGPLFE-LRPDPHIPKHPTQ
LPHSS-RLPSRRDWGHCPKSQTPGSW--SRPAIESSDSGEPPTRDEHCGSGPE---AGAK
SPSP-PPPPGRSVSLLARPSYDYSPAPSSTRSETRVLSETARTPFKSPLLKGISAPVISS
NQVA-TEVQRKKPSVAFKKPVFTYPTPS--PEAVIQTRCPAHAPSSSFTIMALGPPKVSP
KRG-APKTSPRQTLGTPQ--MDTGLQTPRISPSTHEPLEMTSSKSVSPGRKGQLNDS-AS
TP----------PKPSFLGANESPSSQVSSPSLS-SSPSKSHYSPHGCQSAHEKGLQTRL
PVGLKVLMKSPRLLRKSSTVPGKHEKDSLNEASKSS-VAVNKSKPEDSKTPASMEITA-G
ER--NVTLPDSQARDSLAEGLPLETALQESLESSIPGSDGRDGVDNRSMKRSLSS-SKPH
LKPALGMNGAKARSQSFSAHSGEKPSTPP-TEGPGKVRTQIITNTAERGNSLTRQNS--S
MESSPNKAPSVPML--ESLPSAGRPLGHPSSRQGSLGSSGSS-SSQHGSPSKLPLRVPPK
SEGLLIPPGKENQQAFTQGECPS--VAILAEPGSDCHRCPP-T------------P----
-TDCPEALQSPGRTQHPSTFETSSTSKL-ETSGRHP-DASATATDAVSSEAPLSPTIEEK
VMLCIQENVEKGQVQTKPTSVEAKQKP-GPSFASWFGFRKSRLPALSSRKMDVSKTKVEK
KDAKVLGFGNRQLKSERKKEKKKPELQCEVENELLKD-TKS--ADNPDGGLQSKNNRKTP
QDIYNQLKFEPRNRHSP-VTCSTKDTFMTELLNRVDKKAAPQTESGSRNASCRNVLKGSS
QGSCLTGSSISTQGNHKKNMKSKADMEVPKGSLVKQANE-NLQEDEDDAVAD-----SAF
QSHIIESNCQMRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDSEPLLPLQSALPAVSSM
RAQTLEREVPSSTD-SQRPADSAIVHSTSDPIMTARGLQPLQSRLPKPASSGKVSPQKQN
EAE-PRPQTCSSFGYAEDPM--ANQPLPDWGGEDAA-TGTQDKA----------------
------------------------------------------------------------
-----------------------------PRMCTYSASGGSNSDSDLDYGDNGFGAGRGQ
LVKALKSAAPEIETT---------------------------------------------
-

Query Results

"ENSGT00530000063607_1"

ENSGT00530000063607_1