Query Results 

-MENP---EEKKLSITTETSNFTAALKEFEKLVELTAIQKKEERLGLYVKNEDTIDYEKF
YESVLELFGPEIKSQDVKSFYRKLSNNPDASVDWCEIFGYFLSEEDALASQLDEENLVFL
ISRKQRFPLSGGR--KRDVVKCLVKIPQLNFLIIATQKGSITVFNSKMRVQANINVTDTS
WITGCDYLPQLKRIVAVTERTIIIWDYKAQGNSQDSCFVIKPVDHCL-------LCVCVV
PIT-DHLGRDDILMGDDGGFVNRFTLSSDDFGLRQSKHKRKAQSQILDSKNF------KS
VKRKLHNDWVMKINYIQPLHSFGSCSLDSTHSFVLDSLKRLGDNTPVREFSMPRGANTFV
YCIRA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 381)

NVI-VTGGDDKILRLWHPNISTKPVGKLVGHMFSIIELVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYAMIFDQNHGVLVTGSSVI
DMYPLTRMIQDTKQIPHSHDRDINVMVYNRTFHQLLTICSESIIKVWELETGHQIYQIFD
PHGSN

PF00400 // ENSGT00530000063510_2_Domain_4 (546, 577)

VEVTTAAIDKSGFVLATGAYTGTVKLW----DFGSGQEMKMLFEGKDWKEDDH-C
LSQIAFVTTDKKN--HYLILALEFNGKIKLVQGKEGDPLLAVVWELPEIMPILIQGK-QV
I--SLAVTSNPKTMNLTIPEVELTSEDNKPVV--LNISPGISMEVTCFDVLIKEG-YNMI
AT----ATVNGIIILWNFEMSTATQLHRPEDAFNLN-LDLDPTRLKINSILFLFRSKEYA
RKMSQDSVS--------------------SSAQSGG------------------------
------------------------------------------------------------
-LQSSKGKLLKDVLPFTKHSAISLTTLYTDIYARVLLAG--NMEGHVILW-TIGSFLDPP
HEE-KKFKQQI

PF00400 // ENSGT00530000063510_2_Domain_8 (972, 1009)

AWRGHALKIVNVIYVE---DKQVVLTCSVDGS--IRVWHARNGHYCGYF
GQ-----RRKFELNQVSDFILPCDVSERPVEVREESKYTEKKQKYEYPLVFDRNK-----
---WRKMSSFSLLFRRPTPKPFDVNQEFKFFKTLSSPKIRRTVLERSQIGNKEAGIIFGA
LHIYRVP-SPTSLRFLPLIGADAHKESSENFQGKKKGGRVQ---HTQ------------A
RRRSLRRSLAPGVNLISAFFPPIQK------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---QIFRVWDIQT---------LSLMQVFHDSQAGPREAQIFAMLFDNNHGTLITGSAVI
DIYPLTRMIQDTKQVPQTHERNINVLVYNKAFHQVLTICSESVVRVWELETGQLIYQIEN
AHGSN

PF00400 // ENSGT00530000063510_2_Domain_4 (546, 577)

VEVTCAAVDNNGFHLATGACDGTVKTW----DFGSGQELKVLPLGKEINDNEH-W
LLQLVYLNASE-N--RHVILALEYSGIIKIIQANESEAYLSITWSLPDAVSVALQGNS--
-LISLKLSPNAKKTNGFFPDIELLPDKASEQT---NTEIPQGTEVKCFDLLRVEG-YNLL
AT----A-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------SPNEGHVIRW-NVGSFLEEP
RDVKKRIRQQIC

PF00400 // ENSGT00530000063510_2_Domain_8 (973, 1004)

WRAHSTKIVDLFYNE---ERNLVVTASVDCSVSQRLWHSPDGHYFGYF
GQ-----RRLFDISQPTDIILPCDINEHPFTIRDGSKYMEKKQKYEYPLVLDRQR-----
---WKTLTRSSLSLKK--PSPSEIEYDFKFFKALSSPKINKQPLESFKSGNKDAGIVFGS
IPIYR-------------------------------------------------------
-------------------------------

-----------------------------------------------------AIDYDKF
YAKVQELFGPDVKSQDVKCFYRKLCNNLDPSIDWCEIFGYYASEEDSLTAQMDEENLVFL
VSRKQQIVISXXX--XXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXXXXDTS
WITGCDYLSQLKRIVATTERTIIVWDYKSQGSSQENYFVIKPMDHCL-------LCVCVV
SLP-DQLCQDDILLGDDGGFINKFTVNSDDFGLKQAKTKKKSQSQILDSKNF------KS
IKRKLHNDWVMKIRYISPLKCFGSCSLDSVHSLVLESLKRLEDNXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX-
---XVFRVWDIQT---------LSLLQVFHDSMGGPGDMQIYSMLYDTNHGMLITGSSVI
NMYPLTRMIQDTKQIPHSHEREINVMLYNKNFHQVLTICSESIIKVWELDTGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSASLNESGFLFATGAYNGAVKIW----DFGSGQEIKVLPEGKDWKEEEH-W
LIRLIFLKAQEKH--QYLILTLERSGKIKMLQGKEEDIYLVVIWELPDVVPILKTMNR--
-VVHLKMST-DRKTSLPFPSVELITEKHFSQH---VSXXXXXXXXXXXXXXXXXXXXXXX
XX----XXXXXXXXXXXXXXXXXXXXYRPEEGISVE-TDLDPKRFRINDILFLFRTSECV
XXXXXXXXX--------------------XXXXXXX-XX-X--------XXXXXXXXXXX
XXXXXXXEKADV--------TEKSQLS-VNKIHHKG-SNLTESRT-PILVTAHEDGHL--
RLWTIEGRLLKNMLPFTKHSAISLTSLYTDSCARILLTS--NVEGHVILC-SISSFLETP
NEE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLSWRAHSLEIVQVIYVE---DKQIVLTASIDGS--VRLWHAFNGHYCGYF
GQ-----RRIFDLSQTNDFILPCDVTEYPIEIREESKLTEKKQKYEYPLILDRQX-----
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRRHALEGFMTENREAGIVFGS
LPIYRXP-SRTSLRFLPLIGSEAQKDYSDVMSAKRKGGHVQ---HEK-----------PQ
RRRSLKKHFVPQINLASSFFPIIPK------

------------------------------------------MAILLVQTTQAAIDYDKF
YASVQEIFGPEVKNQDVKCFYRKLCKNPDAPIDWCEIFGYFSNEKDALSSKMDEENLIFL
VSRKQRVKIAGSR--RRDEIKCIVKIPQLDLLVTASQKGLLTVFNSQMKVQTSINVTGTS
WITGCDYLLQLKRIVAITERSIIIWDYKAQENSQENYFVIEPMDPRL-------LCVCVV
PMP-EQLYRDDILFGDDSGFVSRFTINSVDFRLKQTKSKRNCQNQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSIHSFVLGSLRRLEDNLPVREFAMPRGANTFC
YCS

PF00400 // ENSGT00530000063510_2_Domain_1 (364, 381)

KANVI-VTGGEDKVLRLWHPNISTKPVGKLVGHMFSVTEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQIFHDTQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLSRMIQDTEHVPHTHKQEINVMLYNKSFHQVLTICSESIIKVWELETGFQIYQISD
AHGYGVE

PF00400 // ENSGT00530000063510_2_Domain_4 (548, 577)

VTSGDIDESGFCFATGAYNGTVKIW----DFGSGQEMKVLPKGKEWKEEEH-W
VKRLIFLKAQEKQ--QNLILALERNGAIKIMQGKENDIFLTVIWELPDAMPYFQNGIH--
-VVHLEMSTRDRNMAIPFPDVKLIVEKKFPHH---TTNPAISTEVNCVNLLQVEG-YNLI
AV----GTVNGVIILWNFVTATVKEVYRPEDSFIVD-SNVDPKHLRINDILFLFRTPECE
R-SSQDSIG--------------------SSSQCDS--SKS--------PQSCKGSRQSI
HDGDVKGEHTDV-T------V-RETHA-VDKKHFGA-ANLIESQP-PILATAHEDGHL--
RLWTMEGRLIKDTLPFTKHSAIPLASLYTDSCARMLLTG--NMEGHVIIF-SINSFLEPP
HDE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QLLSWRAHALEIIQVIYVE---DKQIVLTASIDGS--VRLWHALSGHYCGYF
GQ-----RRNFELSQTSDFILPCDVSEYPIAMKEESNLKEK-ERYEYPLVFDRTR-----
---WRKMSSMSLLFKCTPPKPFEVEHDFKFFKSLSSPKTQRHALESSLSENIKAGIVFGS
LPIYRVP-SPPSLRFLPLIGSDARSESLDGISRRKKGGHVQ---H--E---------KVP
RRRNLKRNLVPQIDLTSYIFPTMPK------

-MSRKKD-CDKESCPALELIDFKNALEQFHNVVEKMIIQKTKERSGLYTKDDDEIDYVKF
YRTIRTLFGPAVKDQNVQTFFRKVMSNPDERPEWPEIFGCFTGESVDMSS-PSKESMVLL
VSEKQQITHSVVK--RKDVIKGIVKVPLLHFTVTASQKGVLTVFNKKMKVLATIEVEAPT
WINGCDFLPNLKYVVAVTESTIILWDYKSKETESD-GFVIKPMKNCM-------LCVCTV
TMA-DDLAKDTILMGDDRGYIYLLTITSDDFIMKQSKGGKESQFKVLDSESF------DI
PKRKLHDDWVGKIRYFSALKCFGSCSTDSINSFILDDIKRLDDHLPVKEFSVP

PF00400 // ENSGT00530000063510_2_Domain_1 (354, 382)

KGVNAFT
YCGKANVI-VTGGNDRIIRLWNPVVNLSPVGKLLGHKHGIVEIVTNEKD-QHIISLSCA-
---KVFRVWDIQS---------LSPLQVFHENHGTPEEMNAFPMVFDNDHGMLFTGSDVI
DIYPLANVIQASKELPQTHEKSLNVLLYNRTFHQVLSICTESVLKVWDLETGSQIYQIED
AHGLNTE

PF00400 // ENSGT00530000063510_2_Domain_4 (548, 577)

VTCAAIEINGVYLATGACDGTVKIW----

ENSGT00530000063510_2_Linker_4_5 (577, 704)

EFESGQEVKALPLEQDSNDEHR--
VLKIVYLKADEGQHA---VIVLEQRGKIKIIQGDSAQTDLYVTWVLPEIVPFPRRNPV--
--VYLSLRPSSLETQDFFPDIRLLCNTSSMRND--KETFLSSV

PF00400 // ENSGT00530000063510_2_Domain_5 (704, 737)

DINCFDVLKVEG-CRLI
AT----GSANGEINLWDFESASVKCLHKTT---------EDSKGSGVNAILFLIRS--V-
-----------------------------SSSRKRSSVSPTPSVRSDASTIPEQESSLNL
HEEEN-AESGEINTEIKTEETASRKNSQ--NPEMSVQLLKAKAGQSPLLASAHESSCV--
RLWSIQGNLMKELLPFSEDPSGPLTALSTDIFTKILLAG--SKKGYIIRW-NMASFLQDP
RNKKNEIKEELCRRAHATKVVELFIEE---E

PF00400 // ENSGT00530000063510_2_Domain_9 (992, 1009)

KNVIVTASIDGS--VRLWHAMTGYYFGYF
GQ-----ARKFELSDTSRLILPSDVSAFPAIIKEDSKRTEKKV--KYPLILDRDK-----
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

-MDIR---EKKHLT-ALQISNFKKSLNGFEKLIEQTAAQKRDEKAGLFIHKEDAIDYDKF
YASVKELFGPDVKNQDVKRFYRRLCNNTDASADWCEIFGYFSS-EDPIASQLDEENLIFF
VSRKQRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQKNYFVIKPMDHCL-------LCVCVV
PLT-DQLCRDDILLGDDGGFVSRFTVNSDDFGLRQAKSERKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTKMIQDTKQIPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVY

PF00400 // ENSGT00530000063510_2_Domain_4 (537, 577)

QILD
SHGFNIEVTSAAINESGFLFATGAYNGTVRIW----DFGSGQEMKVLLEGKDWKEDDH-Y
LRRLMFLKAPEEH--QHLLLALERNGTVKMIQGKEDDIYLMVVWELPGVVPFLQDGKH--
-AVHLRTSTRDRNMALPFPDVELIVERKFSQPT--NKPAINLLRVNCIDLLQVEG-YNLI
AA----GTLSGMIILWNFVTSTVKKVYRPEDCFTVN-PDLDPKRFKINDILFLFRTPECA
RRPSQDSIC--------------------PSFQCES--SKG--------PQSSKGSKQSM
HDSEVKGERTDV--------IAREQQP-VDKKHPGS-ASLPEATP-PILVTAHEDGHL--
RLWTMEGRLLKDMLPFTKHSAISLTSLYADSCARILLAG--NMEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIVKVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRVFELSQTNDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREV-----
---SQ-------------------------------------------------------
------------------------------------------------------------
-RKSLKKNIVPQINLASSFFPAIPK------

-MDAK---DEKRFNLALQINNFKASLVEFNKLVEQTTAQKKEERAGIFIPKEDSIDYDKF
YTSVQQIFGPEVKNQDVKCFYRKLCNNPDAAFDWCEIFGYFSTDEDSLTSQMDEENLVFL
VSRKQRIVIAGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRAQTSTNVTDTS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQEHYFVIKPMDHCL-------LCVCVV
PLP-DQLCRDDILLGDDGGFVNKFTVSSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANSFC
YCGKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMVYDANHGMLITGSGVI
DMYPLTRMIQDTKQVPHTHEREVNVTLYNKYFHQVLTVCSESVIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGLSIELTCAAIDESGYLFATGAYNGTVKIW----DFGSGQEMKMMPEGKDWVEEEH-G
LMRLFFLKPQVKQ--QHLILALERNGTIKIIQGKEDDIFLTVIWELPDAMPYLQYGSH--
-IVHLKMSTKERTMAIPFPDVELIVQKTSQQT---NYSPIVDVDVNCIDVFQTEG-YNLI
AC----GTTNGMIILWNFIAASVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRSPECV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDADVKGEHTDM--------V-GEQQS-ASRKQPVP-ISFVEPQP-PLLVSAHEDGHL--
RLWTLEGKLIKDMLPFTKHSAISLTSLYTDSCCRVLLAG--NVEGHVILC-SISSFMDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQLVLTASIDGS--VRIWNSTSGHYCGYF
GQ-----RRMFDLSQTSDFILPCDVNEYPIEIKEESKFTEKTQKYEYPLIFDRER-----
---WKKMSSMSLLFKRPPLSPFEVQHDFKFFKSLSSPKIRRYALEGFLTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEVQRDSVEGVYMKKK----H----DK------------S
RRKSLKRNLVPQINLASSFFPTTPK------

-MDTR---DDKRFALALQINTFRTALKGFEKLVECTAAQKRDERLGLFIQRKDAIDYDKF
HAAVQELFGPEVKNQDVKCFYRKLCNNPNASMDWSEXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX--XXXXXXXX---XXXXXXXXXXXXXXXXXXXXX-------XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXENYYIIKPMDHCL-------LCMCVA
TLP-DQLCRDDILLGDDGGFVNRYTVNNDDFGLKQAKTKKKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLETLKRLEDNLPVREFSMPRGANTFC
YCIKANVI-ITGGNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX-
---XVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMVYDSNHGMLITGSSVM
DMYPSTRMIQDTKQIPHTHEREINVMLYNKTFHQVLTICSESVIKXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXTVKIW----DFGSAQEMKVLPEGKDWKDEER-L
LKRLIFLKSQEKH--EYFILALECNGKIKMIQXXXXXXXXXXXXXXXXXXXXXXXXXX--
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXX
XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XRSSQDSIC--------------------SSSQYD--SSKS--------PQSSKGSKQSI
HDNEPKGEQRDV--------MVGEQQP-VDKKQTAG-TNLADSQP-PILVTAHEDGHL--
RLWTLEGRLLKNMLPFTKHSAISLTSLYTDSCTRVLLAG--NVEGHVILC-SIGSFLDPP
HDE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLSWRAHALEIIKLIYIE---DKQVVLTASIDGS--VRLWHAFSGHYCGYF
GQ-----RRNFEMSQTADFILPCDVNEHPIEIKEETKFTEKKQKYVYPLIFDREK-----
---WKKMSSMSLLFKRVPPKPFEVERDFKYFKSLSSPKIRGYALEGFLTENREAGIVFGS
LPIYRVS-SPSTLRFLPLIGSETHRDSLDIITGKKKGGHVQ---HEK-----------PQ
RRRSLKRHLVPQINLAASFFPAIPK------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------ENYFIIKPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFINRFTVTSEDFGLKQAKTKKKSQNQVLDSKNF------RX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPVREFSMPRGANTFC
YCAKANVI-VTGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXX-
---XVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSAM
DMYPLTRMIQDTKQVPHTHEREITVTLYNKHFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAIDESGFFFATGAHNGTVKIW----DFGSGQEMKALPEGKDWKEEEH-W
MRHLIFLKAQEKH--QYLVLALERNGSIKMIQGKEDDSYLLMNGELPDXXXXXXXXXX--
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXX
XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XKSSQDSIC--------------------SSSQCD--SSRG--------PQSSKXXXXXX
XXXXXXXXXXXX--------XXXXXXX-XXXXX-XX-XXXXXXXXXXXXXXXXXXXXX--
XXXXXXGRLLKDMLPFTKHSAISLTTLHTDSCTRILLTG--NVEGHVILC-SISSFLDPP
HDE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLSWRAHSLEIIHVVYVE---EKQLVITSSIDGS--VRLWNAFSGHYYGYF
GQ-----RRIFELSQTSDFILPCDVTEYPIEIKEESKFTEKQQKYEYPLIFDRER-----
---WKKMSSLSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYALEGFMTENREAGIVFGS
LPIYRVP-SPTTLRFLPLIGSEAQRESSDGIVGKKKGGHSL---HEK-----------QT
RRKSLKRNLVPQINLASSFFPAIPK------

-MSDGQDSGKGKLSTLSDVTRFNYALKQFQILIGKTVAQKREERIGMYVKDQDEIDYDKF
CEIVQTLFGPEVKDQDVKTFFRKISNNPDGRIEWCEIFGYFIVEGDALASQLDEENMVFL
VSRRQRITKAGVK--RRDVIKCIAKVPQLDFMVTASQKGMLTIFNSQ---------QDSS
WISGCDYLTQLKRVVAVTERTIIVWDYKSQGSSQDNCFIIKPMEHCL-------LCVCTV
NLG-DQQAKDDLLMGDDGGHVSLFTVTSDDFGLKQSKEKKSSHLQILDSRKF------KN
IKRKLHDDWVVKVKFISALNCFGSCSLDSVHSFVLDDLQRLEDNVPVREFSVP

PF00400 // ENSGT00530000063510_2_Domain_1 (354, 381)

RGVNAFT
YCGKANII-VTGGDDKILRLWHPNINTKPVGKLLGHLFSVMEIVTNEKD-QHIISLSTE-
---KIFRVWDIQT---------LSLLQIFHDSQGKPGETQIYAMIFDNNHGTLITGSSVI
DIYPLTRMIQDTKQVPQTHERNINVLTYNRAFHQVLTICAESIVKVWELESGQQIYQIED
AH

PF00400 // ENSGT00530000063510_2_Domain_4 (543, 577)

GPNIEVTCAAIDKNGFHLATGAYDGTLKIW----DFGSGQEIKDLPIANDSKDDEQ-W
LLQLVYLRASE-S--RHVILALEHSGKIKIIQGNEGEPHLTVTWELPEAASLILQGNT--
-VMSLCLKPNANKTNGFFPDVQLLPDTDAKTK---NYSGISGTEMKCFDVLKIEG-YSLI
AT----GNAQGAIILWDFESATVRYLYVPSFSAHA---GQSAQVLGVNAVLFLFRSSTSP
STSLPYSVC--------------------QMYQCISS--RK--------HRQPPGVPSRV
RQDPVPWPHSWV----------GVPSGQSGARPCAL-PNVGPRKCSPILASAHENGCV--
YLWTLGGDLLREVLPFTKHPAIPLITLCTDISAKMLLAATKDTEGHIMRW-NTGSFLEDP
QDENKQIKQQLYW

PF00400 // ENSGT00530000063510_2_Domain_8 (974, 1009)

RAHSTKVVSLFYEE---EKNLVVTASTDGS--VRLWHAPSGHYVGYF
GQ-----RRVFELSESSDMILPCDVNEFPTVIKEDSKYMEKKQKFEYPLVLDREK-----
---WKSLTRSSLLSKK--PRPFEVDQDFKFFKALASPKVNREPLESFKSGNKETGVVFGS
IPIYRVSS----------------------------------------------------
-------------------------------

-MDIG---EEKHINTALQVSSFRTALRGFERLVEHVAAQKRDERAGVFAQKEDAVDYDKF
YKMVQELFGPEVKSQDVKCFYRKLCNNPDASIDWCEIFGYFSSEEESLINQMDQENLVFL
VSRKQRVVISGSR--RRDVIKCIVKVPHLDLLITASQKGMITVFNSQMKVQTSTNVTDTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGNSQENYFVIRPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFVSKFTVNSEDFGLKQAKSKKRLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDNVHSLVLESLKRIEDNLPVREFAMPRGANTFC
YCMKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 381)

NVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIFDSNHRMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNVELTAAAT

PF00400 // ENSGT00530000063510_2_Domain_4 (554, 577)

DESGFLFATGAYNGTVKIW----DFGSGQELKVLPEGKDWKEEEH-W
LHRLIFLKAQEKH--QYLLLSLERNGKIRMIQGKEDDIYLAVIWELPDVVPVLQNGNR--
-IVHLRVSTKERSMAIPFPDVELIVEKNFSQR---VGNSAVSIEVNCIDLLQIEG-YNLI
AA----GTLNGVIILWNFVTSTVKEVYRPEDCFTVD-PDLDPKRFRINDILFLFRNPECV
RRSSQDSVC--------------------SSSQCD--SSKG--------PQSSKGSKQSI
HESEVKGEQTDV--------AMREQQP-VDKKPPGG-TNETDTQPPPILVTAHEDGHL--
RLWTMEGRLLKDILPFTKHAAISLTSLFTDSCARILLTG--NTEGHVILC-SISSFLESP
HDE-KKFKQL

PF00400 // ENSGT00530000063510_2_Domain_8 (971, 1009)

LAWRAHSLEIVQIIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRTFELSQTSDFILPCDVTEYPIEIKEESKFTEKKLTYEYPLVFDRQR-----
---WQKMSSMSLLFRRTPPKAFEVEHDFKFFKSLSSPKIRKHALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRESSDGIHGKKKGGHVQ---HEK-----------VQ
RRRSLKRNLVPQVNLASSFFPTIPK------

-MDIR---EKKRLDTAHQISNFRKCLNVFEKLVEQTAAQKRDERAGLFIHKEDAIDYDKF
YASVKELFGPDVKNQDVKRFYRRLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKQRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLT-DQLCRDDILLGDDGGFVSRFTVNSDDFGLRQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQIPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVY

PF00400 // ENSGT00530000063510_2_Domain_4 (537, 577)

QILD
SHGFNIEVTSAAIDESGFIFATGAYNGTVRIW----DFGSGQEMKVLLEGKDWKEDDH-C
LRRLMFLKAPEEH--QHLLLALERNGTVKMIQGKEDYIYLMVVWELPDVVPFLQDGKH--
-AVHLRTSTRDRNMALPFPDVELIVERKFSQPT--HKSAINLLRVNCIDLLQVEG-YNLI
AV----GTLSGMIILWNFVTSTVKKVYRPEDCFTVN-PDLDPKRFKINDILFLFRTPECA
RRPSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGERTDI--------MAGEQQP-VDKKYPGS-ANLPEVLP-PILVTAHEDGHL--
RLWTMEGSLLKDMLPFTKHSAISLTSLYADSCTRILLAG--NMEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIKVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRVFELSQANDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVERDFKFFKSLSSPKIRRYPLEGFMTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGIEAQKDSSDRITGKKKGGHVQ---HEK-----------AS
RRRSLKRNLVPQINLASSFFPAIPK------

------------------------------------------------------------
------------------------------------IFGYFCSEEDALASQIDEENLIFL
VSRKQRVVISXXXXXXXXXXXXXXXX------------XXXXXXXXXXXXXXXXXXXDTS
WITGCDYLFQLKRIVATTERTIIVWDYKAQGNSQENYFVIKPMDHCL-------LCVCVV
PLP-DQVCRDDILLGDDGGFVTRFTVNSDDFGLKQAKSKKKFQNQVLDSKNF------KS
IKRKLHNDWVMKIRYIPALSCFGSCSLDTIHSLVLDSLKRLEDNXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXDDKVLRLWHPNIST

PF00400 // ENSGT00530000063510_2_Domain_2 (388, 430)

KPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMVYDSNHGMLITXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVWELETGL

PF00400 // ENSGT00530000063510_2_Domain_4 (534, 577)

QIYHILD
PHGFSVELTAAAVNESGLIFATGAYNGTVKVW----DFGSGQELRALPEGKDWKEEEH-W
LHDLIFLKSQEKH--QYLILALERNGKIKIIQXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX---XXXXXXXXXXXX-XXXXXXXX-----XXXXXXXXXXXXXXXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXYRPEDCFTVD-PDLDPKRFRINDILFLFRTPECA
XXXXXXXXX--------------------XXXXXXX--XXX--------XXXXXGSKQSI
HDAEVKGENTNS--------LVGEQ-QFMDKKQYGG-SNLVEAQP-PILATAHEDGHL--
RLWTIEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXGHVILC-SISSFLDPP
HDE-KXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXX--XXLWQALNGHYCGYF
GQ-----RRIFDLAHATDFILPCDVNEYPIEIKEESKFIEKKQKYEYPLIFDRAX-----
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXVP-SPTSLRFLPLIGSETQRDSLDLLPGKKKGGHVQ---HER----------LQG
RRRSLKRNLVPQINLASSFFPSITK------

-MAIS---KEKHFNMALQISNFKKALNEFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDAFADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYLHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPNVVPFLQDGKH--
-AVHLRESTRDRNMAIPFPDVELIVERNASQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HNSEVKGEQTD--V------TVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSSEIIQVIYVE---EKQVVITASIDGS--V--------------
------------------------------------------------------------
--------------------------------------IRRYPLEGFVTENREAGIVFGS
LPIYKIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-MDIR---KEKRLNMALQMSNFKKALNRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKF
YASVQKLFGPDVKNQDVKRFYRKLCNNMDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQDNYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLEVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILE
PHGFNTEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEDEH-C
LRRLIFLKAQEKH--QQLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNFSQPT--DNPTMDLLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVYRPEDCFTVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTDV--------MVGKQQPM-DKKHPGI-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTRDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYSIS-SPTSLRFLPLIGIEAQKDSSDGFTGKKKGGHVQ---REK-----------AP
R-RSLKKNLVPQINLASSFFPAIPK------

-MDIR---EKKHLNTACRISNFRKSLKGFEKLIEQTVAQKRDERAGLFIHKEDAIDYDKF
YASVKELFGPDVKNQDVKRFYRRLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKQRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLT-DQLCRDDILLGDDGGFVSRFTVNSDDFGLRQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQIPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVY

PF00400 // ENSGT00530000063510_2_Domain_4 (537, 577)

QILD
SHGFNIEVTSAAIDESGFIFATGAYNGTVKIW----DFGSGQEMKVLLEGKDWKEDDH-Y
LRRLMFLKSPEEQ--QHLLLALERNGTVKMIQGKEDDIYLMVVWELPDVVPFLQDGKP--
-AVHLRTSTRDRNMALPFPDVELIVERKFSQPT--HKPAINLLQVNCIDSLQVEG-YNLI
AA----GTLSGMIILWNFVTSTVKKVYRPEDCFTVN-PDLDPKRFKINDILFLFRTPECA
RRPSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGERTDV--------VAGEQQS-VDKKHPGS-ANSPESPP-PILVTAHEDGHL--
RLWTMEGRLLKDMLPFTKHSAISLTSLYADSCARILLAG--NMEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIKVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRVFELSQTNDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFNREK-----
---WRKMSSMSLLFKRTPPKAFEVERDFKFFKSLSSPKIRRYPLEGFMTENREAGIVFGS
LPIYRIP-SPTSLRFLPLIGIEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKRNLVPQINLASSFFPAIPK------

-MNVR---GDKRFALALQISNFKTALKRFGKLVERTAAQKRDEKLGLFIQREDAIDYDKF
YAAVQELFGPDVKNQDVKCFYRKLCNNPNASMDWCEIFGYYCSEEDAIASQMDEENLIFL
VSRKERVIISEMVLKRHDNLKIEMILKALCIIVSTHQKWGVTVVDEQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGNTQDNYYIIKPMDHCL-------LCVCVV
TLP-DQLCRDDILLGDDGGFVNRYTVNSDDFGLKQTKAKKKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVK

PF00400 // ENSGT00530000063510_2_Domain_1 (365, 381)

ANVI-ITGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMVYDSNHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKTFHQVLTICSESIIKVWELDTGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TAAAVDESGFLFATGAYNGTLKIW----DFGSGQEMKVLSEGKEWKEEEH-V
WQRLIFLRPQEKQ--QYFLLTLERNGKIKMIQGREDDIFLAVIWELPDIVPVLQDGKW--
-VVPLKTSPTRGSTTLPFPNVELMLEKNLARNAKDCNPPPIGTEVNCIDLLQAEG-YNLI
VA----GTLNGVIILWNFLMSTVTEVFRPEDCLSVD-PDLDPRRFRINDILILFRAPEHA
RRSSQDSIC--------------------SSSQYDS--SKS--------PQSSKGSKQSI
HDNETKGDNTDV--------LAGEHQPVE-KKQPAG-ATPADSHP

PF00400 // ENSGT00530000063510_2_Domain_6 (886, 903)

-PILATAHEDGHL--
RL

ENSGT00530000063510_2_Linker_6_8 (903, 971)

WTLEGRLLKDMLPFTKHSAISLTSLCTDACTRILLAG--NMEGHIILC-SIGSFLDRP
HDE-KKFKQL

PF00400 // ENSGT00530000063510_2_Domain_8 (971, 1009)

LAWRAHALEVVQIIYVE---DRQVVLTASVDGS--VRLWHALNGHYCGYF
GQ-----RRNFEISQMADFILPCDVNEYPIEIKEESKFTEKKQKYEYPLIFDQER-----
---WRKMSSMSLLFKRVPPKPFEVERDFKYFKSLSSPKIRRYALEGFLTENREAGIVFGS
LPIYRVS-SPTTLRFLPLIGTEAQKDSFDAISGKKKGGHVQ---HER-----------PQ
RKKSLKRHLVPQINLATSFFPAIHK------

-VDIS---KEKHLNMALQISNFKKALNGFERLVEQTAAQKRNERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDTSADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCQDDILLGDDGGFVNRFTVNSDDFGIKQARSKRKLQNQALDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNRYFHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLIFLKAQEKH--QQLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNVSQPP--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKEVCRPEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RNIF-----------------------------------SF--------PPIIQGSKQSI
HDSEVKGEQTD--V------MVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKYSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFAS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGIPGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

MD-TK---EQKHLNTELQINNFRTALKGFKNLVEQAAAQKRDERGGLLTQKEDVIDYDKF
YEVVQELFGPEVKSQDVKSFYRKLCNNPDVPIDWCEIFGYFSSEEDSLASQMDEENLVFL
ISRKQRVIISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRVQTSTSVTDTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSGQESYFVIKPMDHCL-------LCVCVV
SLP-NQLCRDDILLGDDGGFVNKFTINSDDFGLKQAKSKKKLQSQVLDSKNF------KS
VKRKLHNDWVMKIRYITPLSCFGSCSLDSVHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCTK

PF00400 // ENSGT00530000063510_2_Domain_1 (365, 381)

ANVI-VTGGDDKVLRLWHPNISTKPVGKLLGHMFSITEIVTNEKD-QHIISLSSA-
---KVFRVWDVQT---------LSLLQVFHDSHGGPGDMQIYSMVYDSNHGMLITGSSVM
DMYPLTRMVQDTKQIPHTHEREINVMLYNRYFHQVLTVCSESIIKVWELETGLQIYQILD
PHGFSVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAALDETGFLFATGAYNGTIKIW----DFGSGQEMKVLPEGKDWKEEEH-W
LRHLVFLKAQEKH--QYLILTLERNGKIKMVQGTEEDLYLVVTWELPNVVPLLQDGNH--
-TVHLKPCPKPRNMHIPFPDVQL-VEKNVSQC---VNSPDISTEVNCIDLLQVEG-YNLI
AA----GTLNGVIILWDFINLTVKELYRPEDCFIVD-PDLDPKRFRINNILFLFRNPECA
RRPSQDSVC--------------------SSSQCDS--SKG--------PQSSKGSKQSI
HDNEVKGEQHDV-T------A-GPQQP-VDKKHPAG-I---DTQP-PVIVTAHEDGHL--
RFWKLEGKLLKNMLPFTKHSAISLTSLCTDLCSRILLTG--NVEGHVILC-SISSFLDPP
HEE-KKLK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QLLVWRAHSLEIVQVIYIE---DKQLVLTASIDGS--IRLWHAFSGHYCGYF
GQ-----RRMFELSQSSDFILPCDVNEYPVEIKEENKFTEKKQKYEYPLVFDRQK-----
---WKKMSSMSLLFKRTPPKAFEVDHDFKFFKSLSSPKIRRRALEGFLTENREAGVVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRESANSIAGKKKGGHVQ---H--D---------KVS
RRKSLKRHLVPQINLASSFFPSIPK------

-MDIR---EEKHFNLALQVSNFRTALGGFEKLVERIAAQKRDERAGFFIQKEDAIDYDKF
YATVQELFGPEVKNQDVKCFYRKLCNNPDASIDWCEXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXSR--RRDVIKCIVKIPQLDLLVTASQKGLITVF-------------DTS
WITGCDYLSQLKRIVATTERTIIVWDHKAQS-SQENYFVIKPMDHCL-------LCVCVV
SLP-DQLCQDDILLGDDGGFVNKFTVNSDDFGLKQAKSKKKLQYQVLDSKNF------KS
VKRKLHNDWVMKIRYISDLNCFGSCSADSVHSLVLESLKRLED

PF00400 // ENSGT00530000063510_2_Domain_1 (344, 382)

NLPVREFSMPRGANTFC
YSRKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNETD-QHVISLSSA-
---KVFRVWNIQT---------LSLLQVFHDSQGGPGDMQIYSMVFDSNHGMLVTGSRVM
DMYPLTRMIQDAKRVPHTHEREINVMLYNKYFHQVLTICSESLIKVWELETGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAIDESGFLFATGAYNGTVKIW----DFGSGQEMKVLPEGKDWKEEEH-W
LQRLIFLKAQEKH--QYLILALERNGKIKMIQGKEDDIYLAVIWELPDVVPVLQNGNR--
-IVHLRMSAKDRSMAIPFPDVELIVEKNFSQY---VDNPAISIEVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFGTSTVKEVYRPEDCFTVD-PDLDPKRFRINDILFLFRKPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKESKQSI
HDSEVKXXXXXXXX------X-XXXXX-XXXXXXXX-X-XXXXXX-XXXXXXXXXXXX--
XXXXXXGRLLKDILPFTKHAAISLTSLYTDSCTRILLTG--NVXXXXXXX-XXXXXXXXX
XXX-XK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

VKQLLSWRAHSLEITQIIYVE---DKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRIFEISQTSDVILPCDVNEYPIEIKEESKFTEKKQKYEYPLVFDRQR-----
---WEKMSSMSLLFKRTPPKTFEVEHDFKYFNSLSSPKIRRHALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDFSDGIPGKKKGSHVQ---H--E---------RVQ
RRRSLKGNLVPQINLTSSFFPAIPK------

-MDIS---KEKHFNMALQISNFKKALNEFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDAFADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYLHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRVSTRDRNMAIPFPDVELIVERNASQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTD--V------TVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVITASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRVPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-MDVK---EEK-HSLSLQIYSFRVALNKFENLVEQIAAQKRDERAGLFIRKEDVIDYDKF
YVSVQELFDIEMKSQDVKYFYRKLCKNPDAPIDWCEIFGYFAAEADSLAYQVDKENLVFL
VSKKQRIATSGSR--RRDVIKCIVKIPQLDLLITASQKGLIRVFNSQMKVQISTNVTDTS
WITGCDYLSQLKRIVATTERTIIVWDYKSQGSTQENYFVIKPMDHCL-------LCVCVV
PLP-DQLCREDILLGDDSGFVSRFTVNSDDFGLKQAKIKKKLQNQILDSKNF------KS
VKRKLHNDWVMKVRYIPSLNCFGSCSLDSVHSLVFESLKRLEDNLPVREFAMPKGANTFC
YCVKANVI-ITGGEDKVLRLWHPYISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQXXXXXXXXXXXSLLQVFHDTQGGPGDMQIYSMVYDTNHGMLITGSSFI
DMYPLTRMIQDTKQVPHTHEQEINVMLYNKYFHQVLTICSESIIKVWELETGVQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

IID
AHGFNVELTSAAIDENGVLFATGACTGTVKIW----DFSSGQEMKVLLEGKDWKEEEH-W
LKHLIFLHAQDKH--QYFILVLECNGTIKMIQGKEDDSFLVVIWELPDAMPYLQDENH--
-TVQMKTSTKDENMAIPFPDVELIIHRNSSQP---TNNPATSFGVNCIDLLQIEG-YNLI
AA----GTINGVIILWNFVASTVKEVYQPKDSSTVD-RDLDPKRFKINDILFLFRTSECA
RRSSQESLC--------------------SSSHCES--SKG--------PQSSKGSKQSI
HDSEVKGEHTDI---------MGEQQP-TSKKGPVP-ANLTEPQP-PFLVTAHEDGHL--
RLWTLEGRLMKDMLPFTKHSAISLTSLYTDSCSRVLLAG--NVEGHVILC-SISSFLDPP
HEE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QVLSWRAHSSAIVQVIYVE---DKQMVLTASVDGS--VRLWHAFNGHYCGYF
GQ-----QRVFDLSQTRDFILPCDVTELPIEIKEEIKFTEKKQKYEFPLILDQQK-----
---WRKMSSTTLLPKHKPPKAFEVQQDFKFFKSLSSPKVRKNALEGFMTENRDAGIVFGS
LPIYRVP-SPTTPRFLPLIGVEAQRESLDSAAARKKGGHVQ---HEK-----------TS
QRKSLKRNLVPQINLASSFFPALSKQRGNPQ

-MDIS---KEKHFNMALQISNFKKALNGFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDLKRFYRKLCNNTDAFADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYLHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFFFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRVSTRDRNMAIPFPDVELIVERNASQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGV-ILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGQYEITSL------LYNKATPFQWTKTPWS-ANFTRSQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVITASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKVSSMSLLFKRTPPKAFEVEQDFKFFRSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

MDFKA---APDDLGIVLQTTNFKTALKGFERLVERTADQKRDERLGLFTQKEXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIFGYFCSEEDMLASQLDEENLIFL
VSRKQRVTISXXXXXXXXXXXXXXXX------------XXXXXXXXXXXXXXXXXXXDTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYYVIKPMDHCL-------LCVCVV
PLT-DQLCRDDILLGDDGGFVNKYTVNSDDFGLKQAKTKKRLQNQVLDSKNF------KS
VKRKLHNDWVMRIRYMPALNCFGSCSLDSVHSLVLDSLSRLEDNLPVREFSMPRGANTFS
YCMKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 382)

NVI-VTGGDDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPNIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHMFSITEIATNEKD-QLVISLSSA-
---KVFRVWDIQT---------LSLVQVFHDSQGGPGDMQIYSMVYDSNHGMLITGSSVI
DMYPLTRMIQDTKQIPHTHEREINVMLXXXXXXXXXXXXXXXXXXVWELETGLQIYQILD
PHGFSVELTAACLEE

PF00400 // ENSGT00530000063510_2_Domain_4 (556, 577)

SGSVFATGAYNGTVKIW----DFGSGQELKALSEGKDWKDEDR-W
LQDLIFLKSQEKH--QYWILTLERSGKIKMIQGKEENIFLTVIWELPEVVPFLHDGNR--
-VVCLRTSANPKSASSPFPDAELILEQKIPHHAHXXXXXXXXXXXXXXXXXXXXX-XXXX
XX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--------------------XXXXXXX--XXX--------XXXXXXX-XX-
XXXXXXXXXXXX--------X-XXXXXXXXXXXXXX-XXXXXXXX-XXXXXXXXXXXX--
XXXXXXGKLLKDMLPFTKHSAISLTSLYVDSCTRILVAG--NMEGHVILC-SIGSFLDPP
YDE-KXXXXXXXXXXXXXXIVHLVYAE---DKQVVVTSSVDDS--VRVWQALNGHYCGYF
GQ-----RRIFDLSQTLDFILPCDVSEYPVEIKEESKFTEKKQKYEYPLVFDQKX-----
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRRHALEGFMTENREAGVVFGS
LPIYRVP-SPASLRLMPLIGSEAQKESLDIISGKKKGGHAQ---HER-------------
-------------------------------

-MDVK---EDK-RSLSFQIYSFRVALNKFENLVEQIAAQKRDERAGLLIRKEDVIDYDKF
YASVQELFDIEMKSQDVKCFYRKLCKNPDAPIDWCEIFGYFSAEADSLAYQMDKENLVFL
VSKKQRIATSGSR--KRDVIKCIVKIPQLDLLITASQKGLIRVHNSQMKVQISTDVTDTS
WITGCDYLSQLKRIVATTERTIIVWDYKSQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DQLCREDILLGDDGGFVSRFTVNSDDFGLKQAKIKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKVRYIPSLNCFGSCSLDSVHSLVFESLKRLEDNLPVREFAMPKGANTFC
YCVKANVI-VTGGEDKVLRLWHPYISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDTQGGPGDMQIYSMVYDTKHGMLITGSIFI
DMYPLTRMIQDTKQVPHTHEQEINVMLYNKYFHQVLTICSESIIKVWELETGVQIYQIID
PHGFNVELTSAAIDENGVLFATGACTGTVKIW----DFSSGQEMKVLLEGKDWKEEEH-W
LKHLIFLHTQDKH--QYFILALEYNGTIKMIQGKEDDSFLVVIWELPDAMPYLQDENHIN
HIVQLKTSTKDGNMAIPFPDVKSIIHRNSSQP---TNNVATTLGVNCIDLLQIEG-YNLI
AA----GTLSGMIILWNFVASTVKEVYRPEDCSTVN-LDLDPKRFRINDILFLFRTSKCA
RRSSQESIC--------------------SSSHCES--SKG--------PQSSKGSKQSI
HDSEVKGERTDI---------MGEQQA-PSKKGPVL-ASLTEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTALYTDSCSRVLLAG--NVEGHVILC-SISSFLDPP
HEE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QVLSWRAHSSEIVQVIYVE---DKQVVLTASVDGS--VRLWHAFNGHYCGYF
GQ-----QRVFDLSQTRDFILPCDVTELPVEIKEESKFTEKKQKYEYPLIFDQQK-----
---WGKMSSATLLPKRAPPKAFEVQQDFKFFKSLSSPKVHRNSLEGFMTENRDAGIVFGS
LPIYRVP-NPTTLRFLPLIGVEAQRESLESALAKKKGSHM-------------------S
RRKSLKRNLVPQINLTSSFFP----------

-MENT-----KDNSSLNEYNNFTEALKKFGKLVEKTVIQKKEERLGTYVKNEDFIDYDRF
YTAVWDLFGPEIKAQDVKSFYRKLSNNPDAPIDWCEIFGYFLSEEDALDSQFDEENLVFL
ISRKQRIGLASGR--KRDVVKCLVKIPQMDFLITATQKGTITVFNSQMRVQATINVTDTS
WITGCDYLSQLKRVVAVTERTIIIWDYKAQGNSKDNCFIIKPMDHCL-------LCVCVV
PMT-EHLCRDDILMGDDGGFVNRFTLNSDDFGFKQSKNKKKLQSQILDAKTF------KN
VKRKLHNDWVMKVKYVQPLNCFGSCSLDSTHSFVLDSLKRLEDNVPVREFSMPRGANTFI
YCLKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 381)

NLI-VTGGDDKILRLWHPNISTKPVGKLVGHMFSITELVINEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDNQGGPGDMQIYAMIFDYNHGVLITGSSVI
DMYPLTRMIQDT

PF00400 // ENSGT00530000063510_2_Domain_3 (493, 528)

KQIPHSHDRDINVMVFNKHFHQLLTVCSESIIKVW

ENSGT00530000063510_2_Linker_3_4 (528, 545)

EVETGHQIYQIFD
PHGS

PF00400 // ENSGT00530000063510_2_Domain_4 (545, 577)

NIEVTTAAVDYSGFVFATGAYNGTIKLW----DFGSGQEMKMLIEGKDWKDDDH-C
LHQITFLKANEKH--QFLILALEYNGKMKLIQGREEDPLLSVIWELPEVVPIFRQEKKDV
I--LLAITSNFKTKNLPIPEVDLVPDEERKSV--SFDSSKVNMEVTCFDVLLTEG-YSLL
AT----ATVNGIIVLWNFVLSTVTEVHRPEDAYVID-PDLDPERLKINAILFLFRGSACI
RRMSEESIT--------------------SSAQSES-TRGG--------ALSSKGSKSSI
HEVDLKGEINTGTK------I----------GQLLQ-STVTEI

PF00400 // ENSGT00530000063510_2_Domain_6 (884, 904)

SP-PIVATAHEDGHL--
RIW

ENSGT00530000063510_2_Linker_6_8 (904, 969)

NMEGNLLKDMLPFTKHSAISLTTLHTDSCSRILLAG--NMEGHIILW-SIGSFLEPP
HEE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QLIAWRGHSLRIVGVLYIE---DKQVVITSSVDGS--IRVWHVRNGHYCGYF
GQ-----RRTFNLSQQTDFILPCDVNEHPVEVKEESKYIEKKQGYEYPLIFDREK-----
---WKKMSSFSLLFRRPTPKPFEVNQEFKFFKALASPKIRKSVLESTSTGNREAGIIFGS
LPIYRVP-SPTSLRFLPLIGADAHKESSENFQGKRKGGRVQ---HLQ------------T
RRKSLRRSLTPGVNLTSSFFPVIPK------

-MDIS---KEKHFNMALQISNFKKALNGFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDLKRFYRKLCNNTDAFADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYLHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFFFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRVSTRDRNMAIPFPDVELIVERNASQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGMIILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTD--V------TVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVITASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-IEVM----DDKVNGELQFNNFRIALKGFEQLVERTAAQKRDERAGLIIPKEDMLDYDKF
YAEVQELFGPEVKNQDVKCYYRKLCNKPDAAIDWCEIFGYYSSGDDYFATQMDEENSGFF
ISKKQQIVIPGSR--RRDVIKSIVKVPQLDLLITASHKGLITVFNNQ----------DTS
WITGCDYLSQLKRVVAVTERTIIVWDYKAQGGNQXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-------XXXXX-X------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VKRKLHNDWVIKIKYISSLKCFGSCSLDSVHSLVVETLKRLDDNXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXX
XXXXVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYAMIYDSNHGMLITGSSVI
SMYPLTRMIQETKQVPHTHEREISAMLYNKYFHQVLTICSESIIKVWELETGLQVYHILD
PHGLNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TCADINESGFLFATGAYNGTVKIW----

ENSGT00530000063510_2_Linker_4_5 (577, 705)

DFGSGQEMKVLPRGKDWKEEEH-S
LKHLIFLKAHEKH--KYLILTLGHNGKIQMVQGKEEEIYLVVIWELPDVLPVLQDENH--
-TIQLKMHAKDKNTNIPFPGVELIAEKDFSN------NPAIGME

PF00400 // ENSGT00530000063510_2_Domain_5 (705, 737)

VNCMDLLQVEE-YNLI
AT----GSLNGVIILWNFVTNTVKEXXXXXXXXXXXRPDMDRKCFRVNDIMF-FRSPECT
XXXXXXXXX--------------------XXXXXXXXXX------XXXXXXXXXXXXXXX
XXXGRKSVMVE-----------D-QQPI--YDNIPG-GIRLDTRP-PLLVTAHEDGHL--
RLWTLEGKLLKNLLPFTKHSAISLTSLHADLCARTLLAG--NMXXXXXXXX--XXXXXXX
XXXXXKFKQLLAWRAHSMEIIRIIYVE---EKQLVITASTDGS--VXXXXXXXXXXXXXX
XX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-----
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQRHPLEGFTSENKEAGIVFGS
LPIYR-------------------------------------------------------
-------------------------------

-MDVS---KDK-RSLSLQIYSFRTALNRLERLVEQIAAQKRDERAGLFTQKEDVIDYDKF
YAAVQELFDIEMRSQDVKCFYRKLCKNPDAPIDWCEIFGYFSAE-DSLAHQVDKENLVFL
VSKKQRIATSGSR--RRDVIKCIVKIPQLDLLITASQKGLIRVFNNQMKVQISTNVTDTS
WITGCDYLSQLKRIVATTERTIIVWDYKSQGNSQENYFVIKPMDHCL-------LCVCVV
PLP-DQLCREDILLGDDGGFVSRFTVNSDDFGLKQTKIKKKLQNHILDSKNF------KS
VKRKLHNDWVMKVRYIPSLNCFGSCSLDSVHSLVFESLKRLGDNLPVREFAMPKGANTFC
YCVKANVI-ITGGEDKVLRLWHPYISTKPVGKLVGHMFSITEIVTNEKD-QHIISLSSA-
---KVFRVWDIQT---------LSLLQVFHDTQGGPGDMQIYSMIYDTKHGMLITGSNFI
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYCHQVLTICSESIIKVWELETGIQIYQIMD
PHGINVELTSAAIDETGVLFATGACTGTLKIW----DFSSGQEMKVLLEGKDWKEEEH-W
LKHLIFLHSQDKH--QYFILALECNGTIKMIQGKEDDTFLVVIWELPDAIPYLQDENH--
-TVQVKTSTKDGNMDIPFPDVELIIHRNSSQH---TNVSFISLIF--LVFLVMKN-YKRA
VYKNIQNNLTNFYVLW----------HQPEGCSTVD-LDLDPKRFRINDILFLFRTTECA
RRSSQESIC--------------------SSSHCES--SKG--------PQSSKVSQKY-
SLISPTGENTDI---------MGEQQS-AGRKGPIP-ANPVEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCSRVLLAG--NVEGHVILC-TISSFLEPP
HDE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QVLSWRAHASEIVQVIYVE---DKQMVLTASVDGS--VRLWHAFNGHYCGYF
GQ-----QRVFDLSQTRDFILPCDVTELPVEIKEESKFTEKKQKYEYPLVFDRQK-----
---WRKMSSTTLLSKRAPPKAFEVQHDFKFFKSLSSPKVRRNALESFMTENKEAGIVFGS
LPIYKVP-SPTTLKFLPLIGVGAQRESLDSMAAKKKGSHGQ---HEK-----------TL
RRKSLKKNLVPQINLASSFFPALPK------

-MDIR---KEKRLNTALQMSNFKKALNRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKF
YASVQKLFGPDVKNQDVKRFYRKLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILE
PHGFNTEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKDDEH-C
LRRLIFLKAQEKH--QQLVLALERNGTIKMIQGKDDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNFSQPT--DNPTMDLLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVYQPEDCFTVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQNSKGSKQSI
HDREVKGEQTDV--------TVGEQQPM-DKKHPGI-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTRDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDGEK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSNGITGKKKGGHVQ---REK-----------AP
RRRSLKKNLVPQINLASSFFPAIPK------

-MDAR---DEKRFNLALQINNFKASLVDFNKLVEQTTAQKKEERAGLFIPKEDAIDYDKF
YASVQQIFGPEVKNQDVKCFYRKLCNNPDAAFDWCEIFGYFSTDEDPLASQMDEENMVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRVQTNTSVTDTS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQEHYFVIKPMDHCL-------LCVCVV
PLA-DQLCRDDILLGDDGGFVTRFTVNSDDFGLKQAKTKKKLQTQVLDSKNF------KS
IKRKLHNDWVMKIRFVPALNCFGSCSLDSVHSLVLESLKRIEDNLPVREFAMPRGANSFC
YCLKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVNNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYAMVYDTNHGMLITGSSVI
DMYPLTRMIQDTKQVPHTHEREVNVMLYNKYFHQVLTICSESVIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFSIELTCATIDDSGFLFATGAYNGTVKLW----DFGSGQEMKMMPEGKDWVEEEH-A
LLRLFFLKSQVKQ--QHFILALERNGTIKMVQGKEDDIILTVIWELPNAMPYLQYGSH--
-IVHLKMSTKERAMGIPFPDVELIVQKSISQQ---TTSSTTNTDVNCIDVFQTEG-FNLI
VS----GTLNGMIILWNFIAASVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRIPECV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDTEVKGEQTDT--------G-SEQQS-VSKKQTAS-TSSAEPQP-PLLVTAHEDGHL--
RLWTLEGKLLKDMLPFTKHSAISLTTLYTDSCCRILLAG--NVEGHVILC-NIGSFMDPP
HDE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1010)

QLLSWRAHSLEIVQVIYVE---DKQLVLTASIDGS--VRLWNSTSGHYCGYF
GQ-----RRMFELSQISDFILPCDVNEYPVEIKEESKFTEKKQKYEYPLIFDRER-----
---WKKMSSMSLLFKRSPPNPFEVQHDFKFFKSLSSPKIRRYALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDSLEGVHSKKKSTHGH----G------------GS
RRKSLKRNFVPQINLASSFFPTTNK------

-MDIR---EEKRFNLEVQTGNFRTALKGFEKLVEHVAAQKREERAGLFIQKEDAIDYDKF
YAAVQELFGPEVKNQDVKCFYRKLCNNPEASTDWCEIFGYFASEKDSLTSQMDEENLVFL
VSRKQRVVISGSR--RRDVIKGIVKVPQLDLLITASQKGLITIF-------------DTS
WITGCDYLSQLKRIVATTERTIVVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
SLP-GQLCRDDILLGDDGGFVNKFTVNSNDFGLKQAKYKKKLQSQVLDAKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSTHSLVLESLKRLEDNLPVREFSMPRGANAFC
YCVKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 382)

NVI-VTGGDDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPSIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHTFSITDIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMVFDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEWEINVMLYNRYFHQVLTICSESIIKVWELETGLQIYQISD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAVDGSGFLFATGAYNGTVKIW----DFGSGQEKKVLPERKDWKEEEH-W
LQRLIFLKAQEKH--QHLLLSLERSGKIRMIQGKEDDIYLAVIWELPDVVRVLQNGNR--
-IVHLRTTTKNRSMAIPIPDVELIIEKNFSQH---ANNPAISTEVNCIDLLQVEG-YNMI
AA----GTLNGVIILWNFVTSTVKEVYRPEDCFTVD-RDLDPKRFRINDILFLFRKPECA
RRSSQDSIC--------------------SSSQCD--SSKG--------PQSSKGSKQSI
HDSEVKGVQTDV--------TGGQQQP-VDKKHLGG-SNLTDTQP-PILVTAHEDGHL--
RLWTMEGRLLKDFLPFTKHAAVSLTSLYTDSCARILLTG--NVEGHVILC-SISSFLDPP
HDE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLAWRAHSLEIIQIIYVE---DKQVVLTASIDGS--VRLWHALSGHYCGYF
GQ-----RRVFEISQTSDFILPCDVNEYPIEIKEESKFTEKKQKYEYPLVFDQER-----
---WKKMSSMSLLFKRTPPKAFEVEHDFKYFKCLSTPKIRRHALEGFKTENRKAGIVFGS
LPIYRIP-SPPSLRLLPLIGSEAQMESPDGISGKKKGRHVQ---HEK-----------TQ
RKKSLKRNLVPQINLTSSFFPSIPK------

-MDIS---KEKHFNMALQISNFKKALNGFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDASADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVK

PF00400 // ENSGT00530000063510_2_Domain_1 (365, 381)

ANVI-VTGGHDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQILD
PHGFN

PF00400 // ENSGT00530000063510_2_Domain_4 (546, 577)

IEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLLEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRVSTRDRNMAIPFPDVELIVERNVSQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTD--V------MVGEQQPV-DKKHPGS-ANLPEAQP-PVLVTAHEDGHL--
RLWTLEGRLLKDLLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QLLSWRAHSLEIIQVIYVE---EKQVVITASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRRMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-MDDT---KE-KRPLSLQVYNFRAALSKFEKLVEQVAAYKRDERA-------DVIDYDKF
YASVQELFDIELKSQDVKCFYRKLCKDPDAPIDWCEIFGYFSTEGDSLAHQLDKENLIFL
VSEKQRIATSGSR--RRDVIKSIVKIPQLDLLITASQKGLIRVFNNQVF-----------
KILGCSPVLSFS---------------------------PSPFPASLLFPSSLIYSLCMF
EVK-RKPY---------------FRVITKIFF------QKMHPGQILKIFVFIGTYLQYA
MITFLMGSWYMYLILI--LFC-----------------------SPLRSLAPSPSLGSLS
FCKRSISLFPYFLLYKVLRLWHPYISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSAK
-----------------------------VTTTGGPGDMQIYSMVYDAKHGMLITGSSFI
DMYPLTRMVQDTKQVPHTHEREINVMLYNKFFHQVLTICSESIIKLPDVI----------
------------------------------------------------------------
------------------------------------------------------------
-------LLQRKNVAIPFPDVELIIHGNSSQC---TNNSDTSFGVNCIDLLQIEG-YNLI
VA----GTLNGMIILWNFVASTVKEVYRPEDCSTVD-LDPDPKRFRINDILFLFRTPECA
RRPSQESIC--------------------SSSHCES--SKG--------AQSSKGSKQSI
QDGEGKGEYADL---------MEE-QQLAGKKGPVP-ANLAEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCSRVLLAG--NVEGHVILC-SIGSFLDSP
HDE-KKFRQ

PF00400 // ENSGT00530000063510_2_Domain_8 (970, 1009)

VLSWRAHSSEIIRVIYVE---DKQLVLTASVDGS--VRLWHAFNGHYCGYF
GQ----------------------------------------------------------
---WRKTSSTTLLSKRAPPKAFEVQHDFKFFKSLSSPKVAK---QSFMTENREAGIVFGS
LPIYRVP-SPTTIKFLPLIGVESQRSK-------------------------------MS
RRKSLKRNLVPQINLASSFFPALVK------

-MDIS---KEKHFNMALQISNFKKALNGFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDAFADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYLHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRVSTRDRNMAIPFPDVELIVERNASQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTD--V------TVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVITASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPTIPK------

-MDAG---KEKWLNNALQVVSFKIALKGFERLVERTAAQKKDEKAGLFTQKEDMINYEKF
FAEVQDLFGMEVKNQDVKCFYRKLCNNPDGPTDWCEIFGYYSSEEDPLASQMNEENLVFL
VSRKQRVVITGSR--RRDVIKCMVKIPQLDLLIAASQRGLITVFNNQ----------DTS
WITGCDYLTQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCAV
PMS-DQLCRDDILLGDDGGFVNKFTVNTDDFGLKQTKTKKKLQNQVLDSKDF------KS
VKRKLHNDWVMKIKFISTLNCFGSCSLDSVHSLVLESLKRLEDNGPVREFSMPRGANTFC
YCIKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 382)

NVI-VTGGDDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPNIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHMFSITEVVTNEKD-QLVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLIAGSTVI
DMYPLTRMIQDTKQVPHTHEREINVMLHNKYFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNIEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAIDDSGFLFATGAYNGTVKIW----DFGSGQELKVLPEGKDWKEEEH-W
VKRLAFLKVQEKH--QHLLLVLEHSGKIKMMQGKENDICLIVIWELPDVIPVLQDGNH--
-IVRLKTSTKDRSMALPFPYVSLIAEKTHPQD---VPNPTVSSEVNCIDILQVEG-YNLI
AA----GTVNGVIILWNFVTSTVKELYRPEDCFTVN-PDLDPKRYRVNDITFLFRTLECA
RKTSQDSVC--------------------SSSQCD--SSKG--------PQSSKGSKQSI
HDGEGK

PF00400 // ENSGT00530000063510_2_Domain_6 (847, 904)

GEQTDI--------IVGEQQP-VDKKHVAS-TGVAEPQP-PVLVTAHEDGHL--
RLW

ENSGT00530000063510_2_Linker_6_8 (904, 967)

NIEGRLLKDMLPFTKHSAISLTSLNIDSCSRILLTS--NVEGHVILC-SVSSFLDPP
HDE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLAWRAHSLEIVQAIYVE---DKQLVLTASVDGS--VRLWHALNGHYCGYF
GQ-----RRSFDLAQTTDFILPCDVNEYPIEIKEESKFTENKQKYDYPLVFDRQR-----
---WQRLSSMALLFKRTPSKPFKVEHDFKFFKSLSSPKIRKHALESFLTENREAGIVFGS
LPIYRVP-SPTSLKFLPLIGSEVIKESSDGVPGKKKAGHVQ---HER-----------MQ
RRKSLKRNLVPQINLSPFFFPVIPK------

-MDIS---EKNGLNTALQIRNFKKSLNRFEKLIEQTAAQKRDERAGLFIHKEDAIDYDKF
HASVKELFGPDVKNQDVKRFYRRLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKQRIFISGSR--RRDVIKSIVKVPHLDLLITATQKGTITVFNNQ----------DTS
WITACDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLT-DQLCRDDILLGDDGGFVSRFTVNSDDFGLRQAKSKRKLQSHVLDSKNF------KS
VKRKLHDDWVMKIRYISALNGFGSCSLDSNHSLVLESLMRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDRVIRLWHPSISTKPVGKLVGHMFSITEIVINEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHSMLITGSSVM
DMYPLTRMIQDTKQIPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVY

PF00400 // ENSGT00530000063510_2_Domain_4 (537, 577)

QILD
SHGFNIEVTCAAIDEIGFLFATGAYNGTVKIW----DFGSGQEMKVLLEGKEWKEDDH-Y
LRRLMFLKAPEEH--QHLLLALERNGTVKMIQGKEDSIYLMVVWELPDVVPFLQDGKH--
-AVHLRMATRDKNMALPFPDVELIVERKSSQPT--NKPAINLLRVNCIDLLQVEG-YNLI
AV----GTLSGMIILWNFVTSTVKKLYRPEDCFTVN-PDLDPKRFQINDILFLFRTPECA
RRPSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGERADV--------MAGEQQP-VDKKHPGS-ANLPEAPP-PILVTAHEDGHL--
RLWTMEGRLLKDMLPFTKHSAISLTSLYADSCARILLAG--NMEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIKVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRVFKLSQTNDFILPCDVTEYPIEIKEESKFTE-KQRYEYPLTFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-RPTSLRFLPLIGIEAQKDSSDGITGKKKGGHVQ---YEK-----------VT
W-RSPKKNLVPQIDLASSFFPAIPK------

-MDTK---DDKRFSLALQINNFKAALVDFDKLVEHTTAQKKDERAGLFIPKEDAIDYDKF
YATVQQLFGPEVKNQDVKCFYRKLCNNPDASFDWCEIFGYFSSEGDSLTSQMDEENLVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRIQTSTNVTDTS
WITGCDYLGQLKRIVATTERTIIVWDHKAQGSSQEHYFVIKPMDHCL-------LCVCVV
PLP-DQLCRDDILLGDDGGFVNRFTVNSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPTLNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANTFC
YCIKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMVYDASHGMLITGSSVI
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELESGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIELTCAAIDESGYLFATGAYNGTAKIW----DFGSGQEMKMLPEGKDWAEEEH-G
LLRLFFLKAQVKH--QHLVLALERNGTIKMIQGKEDDFLLVVIWELPDAMPYLQYGSH--
-IVHLKMSTKERVMAIPFPDVELIVQKSFTQQT--NNNPAIDVEVNCIDLFQTEG-YNLI
VC----GTLNGMIILWNFITATVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRPPDCI
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDTEVKGEQTDM--------V-GEQQP-ASRKQPTP----VEVQP-PIVVTAHEDGHL--
RLWTLEGKLLKDILPFTKHSAISLTSLYTDSCCRTLLAG--NVEGHVILC-SISSFLDQP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---DKQLVLTASIDGS--VRLWHSTSGHYCGYF
GQ-----RRMFELSQTSDFILPCDVNEYPVEIKEETKFTEKKQKYEYPLIFDRER-----
---WKKMSSMSLLFKRTPPKPFEVQHDFKFFKSLSSPKIRRYALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRESVEVVPGKKRGTHVQ---HEK------------S
RRKSMKRNLVPQINLASSFFPALPK------

-MDIR---KEKRLNMALQMSNFKKALNRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKF
YASVQKLFGPDVKNQDVKRFYRKLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSIAEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILE
PHGFNTEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEDEH-C
LRRLIFLKAQEKH--QQLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNFSQPT--DNPTMDLLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVYRPEDCFTVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTDV--------MVGKQQPM-DKKHPGI-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTRDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSVSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYSIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---REK-----------AP
RRRSLKKNLVPQINLASSFFPAIPK------

-MSESKD-YD-ESCSALEVLDFEAALKQFQKLVEKTVTQKTKERLGLYIKDDDEIDYDEF
YRTTQTLFGPEIKEHNVKAFFRKISNNPDAKTEWCEIFGYFIGGNGALPSQLREENTVFL
TSEKQQITYPVVK--ERDMITSIVKVPHLDFTVTSSQKGVLTIFNKK----------DTA
WINGCDFLTQLKCVVAVTERTIIVWDYKSIRTKVDNYFIIKPMENSL-------LCVCTA
TMS-DQLAEDNILMGDDKGYVNLLKVTSDHFGMKQCKGKKESQLQILDSKDF------HI
VKRKLHDDWVLKVKYISDLNCFGSCSSDSIHSFVLDDIKRLKDNLPVKEFSVPRGVNAFA
YCGKAKVI-VTGGHDKLLRLWHPYINTRPTGKLSGHQHSIVEIVTNEKD-QHVISLSFA-
---KIFIVWDLQT---------LSMLQVFQDQ-ESPRGIETLAMVFDNACGTLITGSTVI
DIYPLTHMIQDTKQVPKTHEKSINVLAYNRAFHQILTVCSESILKVWDLETGYQIYQIED

PF00400 // ENSGT00530000063510_2_Domain_4 (541, 577)

AHGLNTEVTCAAIEINGFYLATGACDGTVKIW----DFGSGQEVKALPLTQDSKDEHC--
LLKLVYLKA--NKSQHVLL-VLEQSGKMKIIQGNEIQRYLKVTWVLPEAVLFLQRNAV--
--EFLSLNPGTSQKHEFFPDIQPPSETSSLSSD--AEGFVPSVEMKCFDVLKVEG-HSLI
TT----GSENVLLLWRNFLLYQY---KHHY---------FSGI--KLM------RTARLQ
FLKHQESMLCYSLCI-----------LFFFSYRKISTLTSTAVVS---------------
---------SDI--DSDIDDVPEHKNRYFNQNKVGIAVSGDVKRYTPILASAHENGCI--
YLWSIQGNLLKEILPFSKYHPVPLTAICTDISTKMLLAG--SKEGHIMCW-SIVSFLEDP
QNSKNQIKEELCWMAHSAEVIDLFHEE---QKNVVVTASVDGS--VRLWQAMNGCYLGYF
GQ-----PRKFELSDSSRLILPCDVKGVPIIIKEESKHMEKKS--M----PDRDK-----
---WKSLTRSPSILKK--DKRVDVIQDLKFFKALASPKLPRQPLESIESGSRVTGSVFGH
LPIHKVSTSAPHLLLWCSSSRSP-------------------------------------
-------------------------------

-MDIR---KEKRLNMALQISNFKKALNRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKF
YASVQKLFGPDVKNQDVKRFYRKLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKRRILIS-----------------------------------------------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCV-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRG-----
-------------DDKIIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQILE
PHGFNT

PF00400 // ENSGT00530000063510_2_Domain_4 (547, 577)

EVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEDEH-C
LRRLIFLKAQEKH--QHLVLALECNGTVKMIQGKEDDVYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNFSQPT--DNPAMDLLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTCSVKKVYRPEDCFTVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTDV--------TVGQQQPM-DKKHPGI-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--V--------------
------------------------------------------------------R-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGLEAQKDSSDGITGKKKGGHAQ---REK-----------AP
R-RSLKKNLVPQINLASSFFPAIPK------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------VKVKYISDLNCFGSCSSDSIHSFVLDDIKRLED

PF00400 // ENSGT00530000063510_2_Domain_1 (344, 382)

SLPVKEFSVPKGVNAFI
YCGKAKVI-VTGGHDKFLHLWHPCINSRPTGKLSGHRHSVLE-LTNEKH-QHVIGLSSA-
---KLFCVWNIQT---------LSMLQVFHDNQGIPAELETLIIVFNNDSGTLIAGSTVI
DIYPLTHMIQDMKQVPQTHEKSISVLAYNRTFHQVLTICSQSILKVWDLETGYQIYQIED
AHGLNIEVTCAAIEINAFYLATWAWDGKVYRLNPIMDFKSMTKGECYQVPHNWSH-VTAA
SLKTIYRKISSNNSKILFAFFF--FFDIKMRGGKKKKLYLFVVLPLPGNC----------
----------------------VPCI---FHHD--R---CAHLEFCCIKLMTVY------
------------LNWVA----------------------------AL------MLS----
----------------------------EFGWIKVSTTLSVSLLAC--------------
-------------------------------------------R-----CTVLETKCDQY
EG

PF00400 // ENSGT00530000063510_2_Domain_7 (903, 1010)

WNY-----------------------------TKDSC--LSEGCIMCW-SIVSFLEDP
QNSKR-VRKNLTWRAHSTEVVGLFHEE---EKNVVVTASVDGS--VRLWHATNECYLGYF
GQ-----LRKFELSDISQLILPCDVNSLPIILKEESKHMENKKKFEYPLMLDLHKVLQIM
SKSL------RYHLQF--PKHVNIIQDLKFFKALAFPKIHRQPLEIFESGNRVCGAVFGS
LPIDEVST----------------------------------------------------
-------------------------------

-MSESKD-CD-ENCSALEVLDFKNALKQFQKLVEKIVIQKKKERLGWYIKDDDEIDYDEF
YRTTQTLFGPEVKEHNVKAFFRKISNNPDARTEWCEIFGYFIEGNGATPSHLREENTVFL
TSEKQQITYRVVK--ERDMITSIVKVPHLDFTITSSQKGVLTIFNNK----------DTA
WINGCDFLTQLKCVVAVTERTIIVWDYTSIGISQGNYFIIKPIENSL-------LCVCMV
TMS-DQVGEDNILMGDDKGYVSLLKVTSDHFGLKQCKGKKESQLQILDSKDF------NI
VKRKLHDDWVLKVKYIPDLNCFGSCSSDSIHSFVLDDVKRLEDNLSVEFFVLFLFKRKYC
NCNKQVFI-LTESRKKVKRVRHPCLSRYPAQKLFGYIYISSFVFQLVKE-EILDLKISI-
---RYFIVWDLQT---------LSMLQVFQDQ-DSPKGIETLAMVFDNARGTLITGSTVI
YIYPLTHMI

PF00400 // ENSGT00530000063510_2_Domain_3 (490, 528)

QDTKQVPKTHEKSINVLAYNRAFHQILTVCSESILKVWDLETGYQIYQIED
AHGLNIEVTCAAIEINGFYLATGACDGKPTIT----IFFSGKSQKKFPMSKIKLEKYHPF
YKGLKYFLQPGLQLQQIFEDLQQQGSTYRLFKGNENQRYLKVTWVLPEAVLFLQRNAV--
--EFLSLNPDTLQKHEFFPDIQLPPDTSSLSSD--AEGFVPSVEMKCFDVLKVEG-HSLI
AT----GSENGAIILWDFESATVRYIKEDG---------FKRT--ALMSSLTIMLQDILQ
H--IRQRMNCYIRKTIKTQDLATHSNSFTSSVKKTSSPSSTAVVS---------------
---------SDIVTDSDTDDLPKHKDSYLNQNKPIPNNFMDVRRYSSVLASAHENGCI--
YLWSIQGNLLKEILPFSKYHPVPLTAVCTDISTKMLLAG--SKEGHIMCW-SIVSFLEDP
QNSKNQ

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

IKEELCWMAHSAEVIDLLYEE---QKNVVVTASVDGS--VRLWHAMSGCYLGYF
GQ-----PRKFELSDLSRLILPCDVKDVPMIIKEEGKHTEKKS--M----LDKDNLFLFY
MHRWK-STRSPSIFKK--DKHVDIIQDLKFFKALASPKLPRQPLESTESGSKVAGAVFGH
LPIYEVSTSAS-------------------------------------------------
-------------------------------

-MDTR---EDEQFSLSLQTSNFKAALVDFDKLVEQTMIQKKGERAGLFISKEDAINYEKF
YTTVQHLFGPEVKNQDVKCFYRKLCNNPDAKIDWCEIFGYFSD-EGGLTTQMDEDNLVFL
VSKKQRIEISGSR--RRDVIKCIIKVPQFDLLITASQKGFITVFNSQMRIQTSTNVTDIS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQENYFIIKPMDHCL-------LCVCVV
PLP-DQLYRDDILLGDDGGFVNRFTINSDDFELKQAKTKKKTETQVLDSKNF------KS
VKRKLHNDWVMKIRFIPSLNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANTFC
YCIKANVI-VTGGNDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGNMQIYSMVYDSSHGMLITGSSVI
DMYPLTRMVQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELESGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIELTCAAIDETGFLFTTGAYNGTVKIW----DFGSGQEMKVLPEEKGWKEEEH-A
LLRLFFLKAQVKQ--QYLILALERNGTIKMLQGKEDDALLVAVWELPDVMPYLKCGSH--
-IVHLRMATEERAVPIPFPDVELVIQKSSTQH---ANSPSINAEINCLDIFQLEG-YNLM
VA----GTLNGMIILWNFITATVKEIYRPEDCFTVD-PDLDPKRFRINDIMFLFRPPDCV
RRSSQDSVC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
QENEA----KDI--------A-GEQQS-VAKKQPMP-TNLMEAQP-PILVTAHEDGHL--
RLWTLEGKLLKDMLPFTKYSAISLTTLFTDSCCRTLLAG--NVEGHVILC-SISSFMDTP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---DKQLVLTASIDGS--VRLWYSNTGHYCGYF
GQ-----RRTFELSQPSDFILPCDVNEFPIEIKEESRVTEKKQKYEYPLLFDRER-----
---WKKTSSLSLLFKHTPPKPFEVQHDFKFFKSLSSPKIRRYALEGFVTENKEAGIVFGS
LPIYRVP-SPMSLRFLPLIGSEAQRESVDAVYGKKKGGHM-------------------P
RRQSLKKNLVSQINLSSSFFPTMPK------

-MDSI---EDKEFSLALQINNFKAALVEFDKLVEQTTAQKKDERAGLFIPKEEAIDYEKF
YATVQQLFGPEVKNQDVKCFYRKLCNNPDASFDWCEIFGYFSSEEDPLTSQLDEENLVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRVQTSTNVTDTS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGNSQEHYFVIKPMDHCL-------LCVCVV
PLP-DQLCRDDILLGDDGGFVNRFTVNSDDFGLRQAKTKKKLQSQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNMPVREFAMPRGANTFC
YCVKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMVYDANHGMLITGSSVI
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIELTCAAIDESGFLFATGAYNGTAKIW----DFGSGQEMKMLIEGKDWVEDEH-G
LLRLFFLKAQVKH--QHLVLALERNGTVKLIQGKEDDLFLAVIWELPDAMPYLQYGSH--
-IVHLKMSTKERVMAIPFPDVELIVQKSVVQQ---TNNPAVDVEVNCIDLFQTEG-YNLI
AC----GTLNGMIILWNFITASVKEIYRPEDCFSTD-PDLDPKRFRINDIMFLFRPPDCV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDTEVKGEQADM--------V-GEQQP-VSRKQPTP-TSSMETQP-PILVTAHEDGHL--
RLWTLEGKLLKDILPFTKHSAISLTSLYTDSCCRTLLAG--NVEGHVILC-SISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---DKQLVLTASIDGS--VRVWHSNSGHYCGYF
GQ-----RRMFDLAQTTDVILPCDVNEYPIEIKEESKFTEKQQKYEYPLIFDRER-----
---WKKMSSMSLLFKRTPPKPFEVQHDFKFFKSLSSPKIRRYALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDSVEGVHGRKKGTHVQ---HDK------------S
RRKSLKRNLVPQINLASSFFPVMPK------

--------------------MF-------------------RMAILLVQTTQDAIDYDKF
YASVQELFGPEVKNQDVKYFYRKLCNDPDAPIDWCEIFGYFSNEKDALSSKMDLENLIFL
VSRKQRVKIAGSR--RWDVIKCIVKIPQLDLLVTASQTGLLTVFNSQMKVQTSINVTGTS
WITGCDYLLQLKRIVAITERSIIIWDYKAQENSQENYFVIKPMDHRL-------LCVCVV
PMP-EQLYRDDILFGDDSGFVTRFTINSVDFGLKQTKSKRKFKNQVLNSKNF------KS
VKRKLHNDLVMKIRYIPALNCFGSCSLDSVHSFVLESLKRLEDNLPVREFAIPRGANTFC
YCS

PF00400 // ENSGT00530000063510_2_Domain_1 (364, 381)

KANVI-VTGGEDKVLRLWHPNISTKPVGKLVGHMFSVTEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQIFHDTQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLSRMIQDTEHVPHTHKQEINVMLYNKSFHQVLTICSESIIKVWELETGFQIYQISD
AHGYAVE

PF00400 // ENSGT00530000063510_2_Domain_4 (548, 577)

VTSGAIDESGFCFATGAYNGTVKIW----DFGSGQEMKVLPKGKEWKEEEH-W
VKRLIFLKAQEKQ--QNLILALERNGAIKIMQGKEDDIFLTVIWELPDAMPYFQNGIH--
-VVHLEMSTRDRNMAIPFPDVKLIVEKKFPHH---TTNPAISTEVNCVNLLQVEG-YNLI
AV----GTVNGVIILWNFVTATVKEVYRPEDSFSVD-SNVDPKHLRINDILFLFRTPECE
R-SSQDSIG--------------------SSSQCDS--SKG--------PQSCKGSRQSI
HDGDVKGEHTDV-T------V-RETHA-VDKKHFGA-ANLIESQP-PILATAHEDGHL--
RLWTMEGRLIKDTLPFTKHSAIPLASLYTDSRTRMLLTG--NMEGHVIIF-SINSFLEPP
HDE-MKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QLLSWRAHALEIIQVIYVE---DKQVVLTASIDGS--VRLWHALSGHYCGYF
GQ-----RRNFELSQTSDFILPCDVSEYPIEMKEESNLTEK-ERYEYPLVFDRTR-----
---WRKISSMSLLFKCTPPKPFEVEHDFKFFKSLSSPKTQKYALESSLSENIKAGIVFGS
LPIYRVP-SPPSLRFLPLIGSDARSESLDGISGKKKGGHAQ---H--E---------KAP
RRRSLKTNLVPQINLASSFFPAVPKI-----

-MDNS---EEMRLNATLQVSNFQTSLKEFEKLVEQTAAQKRDERAGLFIQKEDAIDYDKF
YASVQELFGPEVKNQDVKCFYRKLCNNPHASIDWCEIFGYFSSEEDYLASQLDEENLVFL
VSRKQRVVISGSR--RRDVIKCIVKIPQLDLLLTATQKGSITVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQDNYFVIKPMDHCL-------LCVCVV
SLP-DHLCRDDIILGDDGGFVNRFTVNSDDFGLKQAKSKKKSQGQVLDSKTF------KS
VKRKLHNDWVMKVRYISALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCLKANVI-VTGGDDKVLRLWHPNISTKPVGKLLGHMFSITEIVANEKD-QHVISLSST-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIFDANHGMLVTGSNVM
DMYPLTRIIQDTKQIPHTHEREINVMLYNKHFHQVLTICSESIIKVWELETGLQIYQILD
PHGLNVE

PF00400 // ENSGT00530000063510_2_Domain_4 (548, 577)

LTSAAINESGFLFATGAYNGTVKIW----DFGSGQEMKVLPEGKDWKEEEH-W
LQRLIFLKSQEKH--QYLVLALERNGTIKMIQGKEDDIYLMVIWELPDAVPFLRDGSH--
-IVRLKMSRRDRNMALPFPDVELIVERKFSPH---TNNPAIDIAVNCIDILQVEG-YNLI
AA----GTLHGVIILWNFVTSTVKEVYRPEDCFTVD-PDSDPKRFRINDIMFLFRTPECA
RRSSQDSVC--------------------SSSHCD--SSKG--------PQSSKGSKQSI
HDSEVKGEQADV--------MVGEQQP-VDKKHPGG-VNLPEAQP-PILVTAHEDGHL--
RLWTMEGRLLKDMLPFTKHSAISLTSLYTDSCTRVLLAG--NVEGHVILC-SISSFLDPP
HDD-KKFKQLLSWRAHSLQITQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYL
GQ-----RRLFELSQTTDFILPCDVSEYPIEIKEESKFTEKQQKYEYPLIFDRER-----
---WKNMSSMSLLFKRTPRKAFEVEQDFKFFKSLSSPKIRRHALEGFMTENREAGIVFGS
LPIYRVA-SPTSLRFLPLTGSEAQRDSSDGIIGKKKGGHVQ---HER-----------PS
RRRSFKKNLLPQINLASSFFPTMPK------

-MATK---KEKRLNISRQ-IKFKTALNGFEKLVEHIVAQKKDERAGLFVRKEDVIDYDKF
YAAVQELFGPEVKNQDVKCFYRKLCNNPDAPMDWCEIFGYFSSEEDSLASQLDEENLVFL
VSRKQRVVISGSR--RRDVIKCIVKIPQLDLLIAASQKGLITVFNSQ----------DTS
WITGCDYLAQLKRIVATTERTIIVWDYKAQGNSQENYFVIKPMDHCL-------LCVCVV
SLP-DHLCRDDILLGDDGGFVNKFTVNSDDFGLKQAKSKKKSQNQILDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCIKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 382)

NVI-VTGGEDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPNIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHMFSITEIVTNEKD-QLVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDSNHGMLITGSSVI
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAIDESGFLFATGAYNGTVKIW----DFGSGQEM-VLPEGKDWEE-EH-W
L-RLIFLKAQK-H--QHLILT--ERNRIKMIXXXXXXXXXXXXXXXXXXXXXXXXXXX--
-XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXNTAVSREVNCIDLLQVEG-HNLI
AA----GTLNGAIILWNFVTSTVKELYRPEDCFTVD-LDLDPKRFRINDILFLFRTPECA
RRSSLXXXX--------------------XXXXXXX-XXXX--------XXXXXGSKQSV
HDSE----------------------------------------VKPVLATAHEDGHL--
RLWTIEGRLLKDMLPFTKHSAISLTSLHVDSCARILLTG--NVEGHIILS-SIGSFLDPP
HDE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLAWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHAQNGHYCGYF
GQ-----QRFFEISQTSDFILPCDVNEYPIEIKEESKFTEKKQKYEYPLVFDRQR-----
---WRKMSSMSLLFKRVSPKAFEVEHDFKFFESLSSPKXXXXXXXXXXXXXXXXXXIFGS
LPIYKVP-SPTSLRFLPLIGSDVQRESSDGIPGKKKGGHVQ---HEK-------------
-------------------------------

-MDIR---EEKHINTALQVSSFRTALRGFERLVEHVAAQKRDERAGVFAPKEDAVDYDKF
YKMVQELFGPEVKSQDVKCFYRKLCNNPDASIDWCEIFGYFSSEEDSLINQMDEENLVFL
VSRKQRVVISGSR--RRDVIKCIVKIPQLDLLITASQKGMITVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFVSKFTVNSEDFGLKQAKSKKRLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALHCFGSCSLDNVHSLVLESLKRIEDNLPVREFSMPRGANTFC
YCIKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 381)

NVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIFDSNHRVLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TAAAIDESGFIFATGAYNGTVKIW----DFGSGQELKVLPEGKDWKEEEH-W
LHRLIFLKAQEKH--QYLLLSLERNGKIKMIQGKEDDIYLAVIWELPDVVPVLQSGNR--
-IVHLRVSTKERSMAIPFPDVELIVEKNFSQR---VGNPAVSIEVNCIDLLQTEG-YNLI
AA----GTLNGVIILWNFVTSTVKEVYRPEDCFTVD-PDLDPKRFRINDILFLFRNPECV
RRSSQDSVC--------------------SSSQCD--SSKG--------PQSSKGSKQSI
HESELKGEQTDV--------AVREQQP-VDKKPPGG-TNETDAQPPPILVTAHEDGHL--
RLWTMEGRLLKDILPFTKHAAISLTSLFTDSCTRILLTG--NTEGHVILC-NISSFLESP
HDE-KKFKQL

PF00400 // ENSGT00530000063510_2_Domain_8 (971, 1009)

LAWRAHSLEIVQIIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRTFELSQTSDFILPCDVTEYPIEIKEESKFTEKKLTYEYPLVFDRQR-----
---WQKMSSMSLLFKRTPPKAFEVEHDFKFFKSLSSPKIRKHALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRESSDGIHGKKKGSHVQ---HEK-----------VQ
RRRSLKRNLVPQVNLASSFFPAIPK------

-MDIR---EEKHYGTVPQSSNFKAALNEFEKLVEQTAIQKKEERMGLFIQKEDAIDYDKF
YASVQELFGPDLKNQDVKCFYRKLCNNPDAPRDWCEIFGYFSNEEDALASKMDEENLIFL
VSRKQRVIISGSR--RRDVIKCIVKIPQLDLLVTASQKGLITVFNSQ----------DTS
WITGCDYLLQLKRIVATTERSIIIWDYKAQENNQENYFVIKPMDHCL-------LCVCVV
PMP-EQLYRDDILFGDDGGFVSRFTVNSVDFGLKQTKSKRKFQNQVLDSKNF------KS
VKRKLHNDWVMKIRYIPSLNCFGSCSLDSVHSFVLESLRRLED

PF00400 // ENSGT00530000063510_2_Domain_1 (344, 382)

NLPVREFAMPRGANTFC
YCSKANVI-VTGGEDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPNIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVWELETG

PF00400 // ENSGT00530000063510_2_Domain_4 (533, 577)

FQIYQILD
AHGYSVELTSAAVDETGFCFATGAYNGTVKIW----DFGSGQEMKVLPKGKEWKEEEH-W
VKRLIFLKAQEKQ--QHLILTLERSGAIKMIQGKEDDIFLMVIWELPDAIPYLQNGIR--
-VVHLKMSTTDKNIAIPFPDVQLVAEKTFPHH---NSIPTISSEVNCVNLLQVEG-YNLI
AI----GTLQGVIILWNFVTATVKELYRPDDCYNVD-SSMDSKHLRINDILFLFRAPECA
SRSSQDSIC--------------------SSSQCDS--SRG--------PQSSKGSRQSI
HDSDGKGEHTDV-T------V-KESHP-VDKKHLGA-ANLIETQP-PILATAHEDGHL--
RLWTTEGRLLKDILPFTKHSAIPLASLYTDSCARILLTG--NIEGHVIIF-SISSFLEPP
HDE-KKFKQ-LSWRAHALEIIQVIYVE---DKQVVLTASIDGS--VXXXXXXXXXXXXXX
XX-----XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----
---WRKMSSMSLLF-RTPPKPFEVEQDFKFFKSLSSPKTRRYALEGFLAENREAGIVFGS
LPIYRVP-SPPSLRFLPLIGSDARRDSVDGFAGRKKGGHVQ---HEK-----------AS
RKRNLKRNLVPQINLASSFFPAMPK------

MD-IK---EEKHLSTALQISNFKTALKGFEKLLEHVAAQKRDEKAGLFIQKEDAIDYDKF
YAAVEELFGPEVKNQDVKCFYRKLCNNPDVSVDWCEIFGYFSSEEDTLASQMDEDNLVFL
VSRKQRVVISGSR--RRDVIKCIVKIPQFDLLVTASQKGLITVFNSQMRVQTSTTVKDTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSGQENYFVIKPVDHCL-------LCVCVV
SLP-DQVCRDDILLGDDGGFVNKFTVNSDDFGLKQAKAKKKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYIAALSCFGSCSLDSVHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCTKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIISLSSA-
---KVFRVWDIQT---------LSLLQIFHDSQGGPGDMQIYSMVYDSNNGMLITGSGVM
DMYPLTRMVQDTKQIPHTHEREINVMLYNRYFHQVLTICSESIIKVWEIETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFSVELTSAAINESGFLFATGAYNGTIKIW----DFGSGQEMKMLPEGKDWKEEEH-W
LLRLIFLKAQEKH--QYLILTLEHNGKIKMIQGKEDDMCLMVIWELPNVMPMLQSGIH--
-TVHLRTSPQNRSMTIPFPHVEL-IEKNFSQR---ANNPAISMEVNCIDLLQVEG-YNLI
VA----GTLNGVIILWNFVNSTVKEVYRPENCFKVD-PDLDPKRFRINDILFLFRPPECA
RRSSQDSVC--------------------SSSQCDS--SKG--------PQSSKGSKQSI
HDTEVKREQTDV-T------M-GEQHP-GDKKHPGG-TNLIEAQP-PIIVSAHEDGHL--
RLWTMEGKLLKDMLPFTKHSAISLTSLYTDPCTRILLTG--NVEGHVILC-SISSFLDPP
HNE-KKLKQLLAWRAHSLEIVQVIYVE---DKQVVLTASIDGS--VRVWHALNGHYCGYF
GQ-----RRMFEISPTNDFILPCDVNEYPIEIKEENKFTEKTQKYEYPLIFDRQK-----
---WKKMSSMSLLFKRTPPKAFEVDHDFKFFKSLSSPKIRRRALEGFLMENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEARRESSDIIPGKKKGGHT----H--D---------KSQ
RKKSLKRNFVPQINLASSFFPAINK------

-MDAK---DEKRFNLAQQINNFKASLVEFNKLVEQTTAQKKEERAGIFIPKEDSIDYDKF
YTSVQQIFGPEVKNQDVKCFYRKLCNNPDAAFDWCEIFGYFSTDEDSLTSQMDEENLVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQ----------DTS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQEHYFVIKPMDHCL-------LCVCVV
PLP-DQLCKDDILLGDDGGFVNKFTVSSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANSFC
YCSKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMVYDANHGMLITGSGVM
DMYPLTRMIQDTKQVPHTHEREVNVTLYNKYFHQVLTVCSESIIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGLSIELTCAAIDESGYLFATGAYNGTVKIW----DFGSGQEMKMMPEGKDWVEEEH-G
LMRLFFLKPQVKQ--QHLILALERKGTIKIIQGKEDDIFLTVIWELPDAMPYLQYGSH--
-IVHLKTSTKERAMAIPFPDVELIVQKTSQQT---NYSPAVNVDVNCIDVFQTEG-YNLI
VC----GTTNGMIILWNFIAATVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRSPECV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDAEVKGEHTDM--------V-GEQQS-ASRKQPAP-VGSVEPQP-PLLVSAHEDGHL--
RLWTLEGKLIKDILPFTKHSAISLTSLYTDSCCRILLAG--NVEGHVILC-SISSFMDPP
HDE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1010)

QLLSWRAHSLEIIQVIYVE---DKQLVLTASIDGS--VRIWNSTSGHYCGYF
GQ-----RRMFELSQTSDFILPCDVNEYPVEIKEESKFTEKTQKYEYPLIFDRER-----
---WKKMSSMSLLFKRPPLSPFEVQHDFKFFKSLSSPKIRRYALEGFLTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEVQRDSVEGVYMKKKG-HGH----DKVKMEEAPKMAERV
TEEKPEKEFGPTDKSGFILLPIHTQ------

-MDIS---KEKHLNMALQISNFKKALNGFERLVEQTAAQKRNERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDASADWCEIFGYFSSKEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKGIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCQDDILLGDNGGFVNRFTVNSDDFRIKQSRSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIKDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQTMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNVSQPP--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVCRPEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSVVKGEQTD--V------MVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKYSAISLTSLYTDSCTRILLAG--NEEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDRE------
--------------------------------------IRRYPLEGFVTENREAGIVFAS
LPIYRIS-SPTSLRFLPLIGVEAQKDCSDGIPGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-MDIT---KDK-RSLSLQIYTFRVALNRFEKLVEQIAAQKRDEKAGLFARKEEVIDYDKF
YAAVQELFDIEMKSQDVKCFYRKLCKNPDAPIDWCEIFGYFSTETDSLPYQMDKENLVFL
VSKKQRIATSGSR--RRDVIKCIVKIPQLDLLITASQKGLIRVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKSQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DQLCREDILLGDDGGFVSRFTVNSDDFGLKQAKIKKKLQSQILDSKNF------KS
VKRKLHNDWVMKVKYIPSLNCFGSCSLDSVHSLVFESLKRLGDNLPVREFAMPKGANTFC
YCVKANVI-ITGGEDKVLRLWHPYISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDTQGGPGDMQIYSMVYDTKHGMLITGSNFI
DMYPLTRMIQDTKQAPHTHEREINVMLYNKYFHQVLTICSESIIKVWEFETGVQIYQIMD
PHGLNVELTSGAIDETGVLFATGACTGTVKIW----DFSSGQEMKVLLEGKDWKEEEH-W
LRHLIFLHTQDKH--QYFILALEGNGTIKIIQGKEDDTFLVVIWELPDAVPHLQDGNH--
-TVQLKTSTKGGNVDIPFPDVELIIHRNSAQR---TNNPDTSSGVNCIDLLQIEG-YNLI
VA----GTLNGMIILWNFVASTVKEVYHPESCSTVEQQDLDPKRFRINDILFLFRTPECA
RRLSQESIC--------------------SSSHCES--SKG--------AQSSKGSKQSI
QDSEGKGEYTDI---------MGEQQP-AGKKGPNS-ANLTEAQP-PIVVSAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCARVLLAG--NVGRSLLLY-I--------
-WP-EKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QVLSWRAHSSEIVQVTYVE---EKQMVLTASVDGS--VRMWHAFNGHYCGYF
GQ-----QRVFDLSQTKDFILPCDVTELPIEIKEESKFTEKKQKYEYPLIFDRQK-----
---WRKMSSTTLLSKRAPRKAFEVQHDFKFFKSLSSPKVRRNALEAFMTENREAGIVFGS
LPIYRVP-SPTTLRFLPLIGAEAQRESVDSMAAKKKV-----------------------
--SYLKRNLVPQINLASSFFPALTK------

-MDSR---EEKHLNIALQISSFRAALKEFEKLAERVAAQKRDERAGLFIQKEDAIDYDKF
YATVQELFGPEVKNQDAKCFYRKLCNNLDASIDWCEIFGYFSSEEDSLASQMDEESLVFL
VSRKQRITISGSR--RRDVIKCIVKIPQLDLIITASQKGLITVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCTV
SLP-DQLCRDDILLGDDGGFVNKFTVNSDDFGLKQAKSKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSAHSLVLDSLKRLEDNLPVREFAMPRGANTFC
YCIKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 381)

NVI-VTGGDDKVLRLWHPSISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIFDSNHGMLVTGSSVV
DMYPLTRMIQDTKQIPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAIDETGFLFATGAYNGTVKIW----DFGSGQEMKVLPEGKDWKEEEH-W
LHRLVFLKAQEKH--QYLILALERNGKIKMLQGKEDDVCLVAIWELPDVVPVLQSGSR--
-VVHVRTSTKDRSMAIPFPDVELMVEKHSSQH---VTNPAISVEVNCIDLLQVEG-YNLI
AA----GTLNGMIILWNFVTSTVKEVYRPEDCFTVG-ADLDPKRFRINDILFLFRSPECA
RRSSQDSIC--------------------SSSHCD--SSRG--------PQSSKGSKQSI
HESEVKGEQTDV--------TAREQHP-VDKKRPGG-TNLTDAQP-PILVTAHEDGHL--
RLWTMEGKLLKDMLPFTKHSAISLTSLYTDSCARILLTG--NMEGHVILC-GISSFLDPP
HDE-KKFKQ

PF00400 // ENSGT00530000063510_2_Domain_8 (970, 1009)

VLAWRAHSLEIIQVIYVE---DKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRMFEISQTSDFILPCDVNEYPIEIKEESKFTEKKQKYEYPLVFDKQR-----
---WKKMSSMSLLFKRTPPKTFEVEHDFKFFKSLSSPKIQRRALEGFMTENREAGIVFGS
LPIYKVP-SPTSLKFLPLIESEPQRESPDGIPGKKKGGHVQ---HEK-----------SP
RRRSLKRNLIPQINLASSFFPAIPR------

-MDAK---DEKRFNLALQINNFKASLVEFNKLVEQTTAQKKEERAGIFIPKEDSIDYDKF
YTSVQQIFGPEVKNQDVKCFYRKLCNNPDAAFDWCEIFGYFSTDEDSLTSQMDEENLVFL
VSRKQRIVIAGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQ----------DTS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQEHYFVIKPMDHCL-------LCVCVV
PLP-DQLCRDDILLGDDGGFVNKFTVSSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANSFC
YCGKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIASNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMVYDANHGMLITGSGVI
DMYPLTRMIQDTKQVPHTHEREVNVTLYNKYFHQVLTVCSESIIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGLSIELTCAAIDESGYLFATGAYNGTVKIW----DFGSGQEMKMMPEGKDWVEEEH-G
LLRLFFLKPQVKQ--QHLILALERNGTIKIIQGKEDDIFLTVIWELPDAMPYLQYGSH--
-IVHLKMSTKERTMAIPFPDVELIVQKTSQQT---NYSPAVDVDVNCIDVFQTEG-YNLI
VC----GTTNGMIILWNFIAASVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRSPECV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDTDVKGEHTDM--------V-GEQQS-ASRRQPVP-ISSVEPQP-PLLVSAHEDGHL--
RLWTLEGKLIKDMLPFTKHSAISLTSLYTDSCCRILLAG--NVEGHVILC-TISSFMDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---DKQVVLTASIDGS--VRIWNSTSGHYCGYF
GQ-----RRMFDLSQTSDFILPCDVNEYPIEIKEESKFTEKTQKYEYPLIFDRER-----
---WKKMSSMSLLFKRPPLSPFEVQHDFKFFKSLSSPKIRRYALEGFLTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEVQRDSVEGVYMKKK----H----DKVKMEEACKMAEGS
RRKSLKRNLVPQINLASSFFPTTPK------

---------------ALQVINFRASLKAFENLVEKTAACKRDERAGIFVQKEEAIDYDKF
YAAVQDLFGPEVKNQDVKGFYRKLCSNPDGFIDWCEIFGYFTSEEDSLAAQLDEENLIFL
VSRKQRVVISGSS--RRDVIKCIVKIPQLDLLLTATQKGSIAVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFIIKPMDHCL-------LCVCVV
SLP-DHLCRDDILLGDDGGFVNKYTVNSDDFGLKQAKSKKKLQNHILDSKSF------KS
VKRKLHNDWVMKVRYIPALNCFGSCSLDSVHSLVLETLKRLEDNMPVREFSMPRGANTFC
YCVKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 381)

NVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQIPHTHEREINVMLYNKHFHQVLTICSESIIKVWELETGLQIYQILD
PHGMNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAVNESGFLFATGAYNGTVKIW----DFGSGQEMKVLPEGKDWKEEEH-W
IQSLFFLKSQEKH--QHVVLVLERNGTIKMIQGKEDDFYLMVIWELPDIIPFLQDGTR--
-TVHLSTSSKEKNAALPFPHIKLIVERNVSLH---TNNPIAGLEVNCIDILQIEG-YNLI
VA----GTLNGVIILWNFVTATVKEVFRPEECSPAN-SELDPKRFRINDILFLFRTPECI
RRSSQESVC--------------------SSSHCE--SSKG--------PQSSKGSKQSI
HDSEGKGEQTDV--------TVGEQQP-ADKKHPGS-ASLP

PF00400 // ENSGT00530000063510_2_Domain_6 (882, 904)

EAQP-PIIVTAHEDGHL--
RLW

ENSGT00530000063510_2_Linker_6_8 (904, 969)

NMEGKLLKDMLPFTKHAAISLTSLYTDSCTRLLLAG--NVEGHVILC-SISSFLDPP
HDE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYL
GQ-----RRFFELSQTGDFILPCDVSEYPIEIKEESKFTEKHQKYEYPLVFDRER-----
---WKNMSSMSLLFKRTPPKAFEVEHDFKFFKSLSSPKIRRHALEGFMTENREAGIVFGS
LPIYRVA-SPTTLKFLPLIGAEAQRESVDGIPGKKKGGHVQ---HER-----------GG
RRKSLKKNFVPQINLATSFFPSVPK------

-MDIR---KEKRLNTALQISNFKKALKRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKF
YASVQKLFGPDVQNQDVKRFYRKLCNNTDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLS-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKFKRKLQN----------------
---QLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNTEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEDEH-C
LRRLIFLKAQEEH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAVPFPDVELIVERNFSQPT--DNPAMDLLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVYRPEDCFTVN-SDLDPKHFKINDILFLFRTPECA
RRLSQDSIC--------------------SSSQCES--SKG--------PRSSKGSKQSI
HDSEVKGEQTDV--------TVGEQQPV-DKKHPEN-ANLPKAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWL---------IYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDIILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFQSLSFPKIRRYPSE-------EAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITAKKKGGHVQ---REK-----------AP
RRRSLKKNLVPQINLASSFFPAIPK------

-MDAK---DEKRFNLALQINNFKASLVEFNKLIEQTTAQKKEERAGIFIPKEDSIDYDKF
YTSVQQIFGPEVKNQDVKCFYRKLCNNPDAAFDWCEIFGYFSTDEDSLTSQMDEENLVFL
VSRKQRIVIAGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQ----------DTS
WITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQEHYFVIKPMDHCL-------LCVCVV
PLP-DQLCRDDILLGDDGGFVNKFTLSSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFGMPRGANSFC
YCGKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMVYDANHGMLITGSGVI
DMYPLTRMIQDTKQVPHTHEREVNVTLYNKYFHQVLTVCSESVIKVWELETGLQIYQI

PF00400 // ENSGT00530000063510_2_Domain_4 (539, 577)

LD
PHGLSIELTCAAIDESGYLFATGAYNGTVKIW----DFGSGQEMKMMPEGKDWVEEEH-G
LMRLFFLKPQVKQ--QHLILALERNGTIKIIQGKEDDIFLTVIWELPDAMPYLQYGSH--
-IVHLKMSTKERTMAIPFPDVELIVQKTSQQT---NYSPAVDVDVNCINVFQTEG-YNLI
VC----GTTNGMIILWNFIAASVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRSPECV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HDADIKGEHTDM--------V-GEQQS-ASRKQPVP-ISFVEPQP-PLLVSAHEDGHL--
RLWTLEGKLIKDMLPFTKHSAISLTSLYTDSCCRILLAG--NVEGHVILC-SISSFMDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQLVLTASIDGS--VRLWNSTSGHYCGYF
GQ-----RRMFDLSQTSDFILPCDVNEYPIEIKEESKFTEKTQKYEYPLIFDRER-----
---WKKMSSMSLLFKRPPLSPFEVQHDFKFFKSLSSPKIRRYALEGFLTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEVQRDSVEGVYMKKK----H----DKVKREEAPEMAEGS
RRKSLKRNLVPQINLASSFFPTTPK------

-MDIS---KEKHFNMALQISNFKKALNGFEKLVEQTATQKRDERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDLKRFYRKLCNNTDAFADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKVPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYLHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFFFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLVFLKAQEKH--QHLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRVSTRDRNMAIPFPDVELIVERNASQPS--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVCRLEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTD--V------TVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVITASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGITGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-MDFG---EEKHINTALQVSSFRTALRGFERLVEHVAVQKRDERAGVFAQKEDAVDYDKF
YKMVQELFGPEVKSQDVKCFYRKLCNNPDASIDWCEIFGYFSSEEESLINQMDQENLVFL
ISRKQRVVISGSR--RRDVIKCIVKVPHLDLLITASQKGMITVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGNSQENYFVIKPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFVSKFTVNSEDFGLKQAKSKKRLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDNVHSLE--------NSLPAERFK---------
LC---------------------PSATKPVGKLVGHMFSITEIVTNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIFDSNHRMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNVELTAAAIDESGFLFATGAYNGTVKIW----DFGSGQELKVLPEGKDWKEEEH-W
LHRLIFLKAQEKH--QYLLLSLERNGKIRMIQGKEDDIYLAVIWELPDVVPVLQNGNR--
-IVHLRVSTKERSMAIPFPDVELIVEKNFSQR-----NSAVSIEVNCIDLLQIEG-YNLI
AA----GTLNGVIILWNFVTSTVKEVYRPEDCFTVD-PDLDPKRFRINDILFLFHNPECV
RRSSQDSVC--------------------SSSQCD--SSKG--------PQSSKVSKR--
-------KGEYV--------AMREQQP-ADKKPPGG-TNETDTQPPPILVTAHEDGHL--
RLWTMEGRLLKDILPFTKHAAISLTSLFTDSCARILLTG--NTEGHVILC-SISSFLESP
HDE-KKFKQLLAWRAHSLEIVQIIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRTFELSQTSDFILPCDVTEYPIEIKEESKFTEKKLTYEYPLVFDRQR-----
---WQKMSSMSLLFKRTPPKAFEVEHDFKFFKSLSSPKIRKHALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRESSDGFHGKKKGGHKILCAPEY-----------VQ
RRRSLKRNLVPQVNLASSFFPAIPK------

-MDPR---EEKQFKQTLQINNFKLALSRFENLVELTAAQKREERAGLFIPKEEVIDCDKF
YELVQQFFGPEVKNQDVKCFYRKLCNKPNASIDWCEIFGYFSTEEDPLAAQLDEENLIFL
VSRKQRIVISGSR--RRDVIKSIVKIPQLDLLITASQKGLITVFNNQMKVQSRTNVTDTS
WITGCDYLAQLKRIVATTERTIIVWDYKAQGSSQDHYFVIKPMDHCL-------LCVCVV
TLP-DQLCRDEILLGDDGGFVNRFTVNSDDFGLKQAKTKKKVQSQILDSKNF------KS
TKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANTFC
YCLKANVI-VTGGDDKILRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMVYDSMHGMLITGSSVM
DMYPLTRMVQDTKQIPHTHEREINVMLYNKSFHQVLTICSESIIKVWELDTGLQI

PF00400 // ENSGT00530000063510_2_Domain_4 (536, 577)

YHILD
PHGFGVELTCADIDENGVLFATGASNGTIKIW----DFISGQEIKVLLEGKDWKEEDH-W
LQRLIFLKGHEKQ--KYLILALESNKTIKMIQGKEEDISLTVLWELPDVIPYLQLSSH--
-TVHLKTK--DMNDTIPFHAVELIAQKSFSQN---VRSPAISTEVNCIDLLEAEG-FNLI
VA----GTLNGMIILWNFTTSSVKDVYRPEDCFNTD-PDLDPKRYRINDILFLFRTPECA
RKLSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSKQSI
HESEVKGEQTDN--------V-SEQQT-ASKKHLAA-TTIVEAQP-PLLVTANEDGHL--
RLWTMEGKLLKDMLPFTKHSAISLTSLYTDSCNKILLAG--NMEGHVILC-SIGAFLDPP
HDE-KKF

PF00400 // ENSGT00530000063510_2_Domain_8 (968, 1009)

KQLLSWRAHSLEIVQVAYVE---DKQVVVTASVDGS--VRLWHAVNGHYCGYF
GQ-----RRALDLTMAMDFILPCDVTECPIEIKEESRFTEKKQKYEYPLIFDRER-----
---WKNMSSMSLLFRRAPPKAFEVEHDFKYFKSLSSPKIRRCALEGFMTENREAGIVFGS
LPIYR-------------------------------------------------------
RKRSLKRTLVPQINLAASFFPIMNK------

-MDIR---KEKRLNMALQMSNFKKALNRFEKLVEQTAAQKRDERAGLFIHKEDAIGYDKF
YASVQKLFGPDVKNQDVKRFYRKLCNNMDASADWCEIFGYFSSEEDPIASQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQDNYFVIKPMDHCL-------LCVCVV
PLP-DHLCRDDILLGDDGGFVNRFTVNSDDFGIKQAKSKRKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHVVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLEVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILE
PHGFNTEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEDEH-C
LRRLIFLKAQEKH--QQLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNFSQPT--DNPTMDLLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKKVYRPEDCFTVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTDV--------MVGKQQPM-DKKHPGI-ANLPEVQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTRDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKTSSMSLLFKRAPPKAFEVEQDFEFFKSLSSPKIRRYPLEGFVTENREAGIVFGS
LPIYSIS-SPTSLRFLPLIGVEAQKDSSDGFTGKKKGGHVQ---REK-----------AP
Q-RSLKKNLVPQINLASSFFPAIPK------

MD-IG---KEKRLSIALQISNFRTALKGFEKLVEHVAAQKRDERAGLFIQKEDVIDYDKF
YAAVRELFGPEVKNQDVKCFYRKLCNNPDASTDWCEIFGYLSSEE-SPASHMDEENLVFL
VSRKQRVVISGSR--RRDVIKCIVKIPQLDLLITASQKGLITVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSGQENYFVIKPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFVNKFTVNSDDFGLKQAKSKKKLQSQVLDSKNF------KS
VKRKLHNDWVMKIRYITPLSCFGSCSLDSVHSVVLESLKRLEDNLPVREFSVPRGANTFC
YCMKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 382)

NVI-VTGGDDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPNIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHMFSITEIVVNEKD-QHVISLSSA-
---KAFRVWDIQT---------LSLLQVFHDSHGGPGDMQIYSMVYDASHGMLITGSSVM
DMYPLTRMVQGTRQIPRTHEREINIMLYNRYFHQVLTICSESIMRVWELETG

PF00400 // ENSGT00530000063510_2_Domain_4 (533, 577)

LQVYQILD
PHGFSVELTSAAVDETGFLFATGAYNGTIKIW----DFGSGQEMKVLPEGKDWKEEEH-W
LRHLIFLKAQEKQ--QYLILALERNGKIKMVQGKEEDACLMVIWELPNVVPFLQDGNH--
-TVHLKTAPKHRSMRIPFPDVEL-VEKNFSQS---VHSPAISMEVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVNSTVKELYRPEDCFTAD-PDLDPKRFRINNILFLFRTPECA
RDSIHPIYL--------------------IPLQFHRNTFSF--------SPLIQGSKQSI
HDSDVKGEQTDV-T------A-

PF00400 // ENSGT00530000063510_2_Domain_6 (863, 904)

GDQQP-VDTKHPGG-TSVIDTQP-PVIVTAHEDGHL--
RFW

ENSGT00530000063510_2_Linker_6_8 (904, 967)

TLEGKLLKNMLPFTKHSAISLTSLYTDSCARILLTG--NVEGHVILC-SISSFLDPP
HEE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

LKQLLAWRAHSLEVTQVIYVE---DKQMVLTASIDGS--VRLWHAFSGQYCGYF
GQ-----RRMLEISQTSDFILPCDVNEYPVQIKEENKFTEKQQKYEYPLVFDRQK-----
---WKKMSSMSLLFKRTPPKAFEVDHDFKFFKSLSSPKIRRHALEGFLKENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEMQRESVDSIPGEKKESHVQ---H--E---------ATS
WRRSLKRHLVPQINLASSFFPSISE------

-MDVK---EEK-HSLSLQIYSFRVALNKFENLVEQIAAQKRDERAGLFIRKEDVIDYDKF
YVSVQELFDIEMKSQDVKYFYRKLCKNPDAPIDWCEIFGYFAAEADSLAYQVDKENLVFL
VSKKQRIATSGSR--RRDVIKCIVKIPQLDLLITASQKGLIRVFNSQMKVQISTNVTDTS
WITGCDYLSQLKRIVATTERTIIVWDYKSQGSTQENYFVIKPMDHCL-------LCVCVV
PLP-DQLCREDILLGDDSGFVSRFTVNSDDFGLKQAKIKKKLQNQILDSKNF------KS
VKRKLHNDWVMKVRYIPSLNCFGSCSLDSVHSLVFESLKRLEDNLPVREFAMPKGANTFC
YCVKANVI-ITGGEDKVLRLWHPYISTKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDTQGGPGDMQIYSMVYDTNHGMLITGSSFI
DMYPLTRMIQDTKQVPHTHEQEINVMLYNKYFHQVLTICSESIIKVWELETGVQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

IID
AHGFNVELTSAAIDENGVLFATGACTGTVKIW----DFSSGQEMKVLLEGKDWKEEEH-W
LKHLIFLHAQDKH--QYFILVLECNGTIKMIQGKEDDSFLVVIWELPDAMPYLQDENH--
-TVQMKTSTKDENMAIPFPDVELIIHRNSSQP---TNNPATSFGVNCIDLLQIEG-YNLI
AA----GTINGVIILWNFVASTVKEVYQPKDSSTVD-RDLDPKRFKINDILFLFRTSECA
RRSSQESLC--------------------SSSHCES--SKG--------PQSSKGSKQSI
HDSEVKGEHTDI---------MGEQQP-TSKKGPVP-ANLTEPQP-PFLVTAHEDGHL--
RLWTLEGRLMKDMLPFTKHSAISLTSLYTDSCSRVLLAG--NVEGHVILC-SISSFLDPP
HEE-KKFK

PF00400 // ENSGT00530000063510_2_Domain_8 (969, 1009)

QVLSWRAHSSAIVQVIYVE---DKQMVLTASVDGS--VRLWHAFNGHYCGYF
GQ-----QRVFDLSQTRDFILPCDVTELPIEIKEEIKFTEKKQKYEFPLILDQQK-----
---WRKMSSTTLLPKHKPPKAFEVQQDFKFFKSLSSPKVRKNALEGFMTENRDAGIVFGS
LPIYRVP-SPTTPRFLPLIGVEAQRESLDSAAARKKGGHVQ---HEK-----------TS
QRKSLKRNLVPQINLASSFFPALSKQRGNPQ

-MESS---EDKQSSITNEFNNFTDALHKFRTLVETTTIQKKEERLGLYVKNEDTIDYEKF
YESVLELFGPEIKSQDVKSFYRKLSNNPDAPVDWCEXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXGR--KRDVVKCLVKIPQLDFLIIATQK

PF00400 // ENSGT00530000063510_2_Domain_0 (159, 206)

GSITVFNSQ----------DTS
WITGCDFLPQLKRVVAVTERTIIIWDYKAQGNSQXXXXXXXXXXXXXXXXXXXXXXXXXX
XXX-------XXXXX-X------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VKRKLHNDWVMRIKYIQPLNCFGSCSLDSIHSFVLESLKRLEDNMPVREFSMPRGANTFV
YCVKANAI-VTGXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXX
XXXXVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYAMIFDYNHGMLVTGSSVI
DMYPLTRMIQDTKQIPHSHDRDINVMVYNRTFHQLLTICSESVIKVWELETG

PF00400 // ENSGT00530000063510_2_Domain_4 (533, 577)

HQIYQIFD
PHGSSIEVTAAAVDKSGFVLATGAYNGTLKLW----DFGSGQEMKVLVEGKDWKEDDR-C
LHQLTFLTTSEKN--HFLILALEYNGRIKLVQGKEDDPLLAVIWELPEVMPTFIRGEK--
-VISLTVSCKPRTLSIPIPEVELVMKMSLSQ------Y--NELVVTCFDVLIMEG-YNLI
AT----ATVNGIIILWNFVLCTVTEHRPED--ALVLDPDLNPERLKINAMLF-LXXXXXX
XXXXXXXXX--------------------XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXQ
HSGGRKGEQLR-----------AKKRHR--Y----I-TNLNEL

PF00400 // ENSGT00530000063510_2_Domain_6 (884, 904)

SP-PILVTAHEDGHL--
RLW

ENSGT00530000063510_2_Linker_6_8 (904, 967)

SMEGKLLKDMLPFTKHSAISLTTLYTDVCARLLLAG--NMXXXXXXXX--XXXXXXX
XXXXXK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLIAWRGHALKIVGVIYVE---DKQVVLTASVDGS--VRVWHARNGHYCGYF
GQ-----RRTFELNQVTDFILPCDVSEYPVEVKEESKYTEKKQKYEYPLIFDREX-----
---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIRRNVLESTVTGNREAGVIFGS
LSIYR-------------------------------------------------------
-------------------------------

-VDIG---KEKHLNMALQISNFKKALNGFERLVEQTAAQKRNERAGLFIHKEDAIDYDKF
YASVQKLFGPDVKDQDVKRFYRKLCNNTDTSADWCEIFGYFSSEEDPITSQLDEENLVFF
VSRKRRILISGSR--RRDVIKSIVKIPHLDLLITATQKGLITVFNNQ----------DTS
WITGCDYLLQLKRIVATTERTIIVWDYKAQGSSQENYFVIKPMDHCL-------LCVCVV
PLP-DHLCQDDILLGDDGGFVNRFTVNSDDFGIKQARSKRKLQNQALDSKNF------KS
VKRKLHNDWVMKIRYISALNCFGSCSLDSNHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCVKANVI-VTGGDDKVIRLWHPNISTKPVGKLVGHMFSITEIVTNEKD-QHIVSLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMIYDANHGMLITGSSVM
DMYPLTRMIQDTKQVPHTHEREINVMLYNKYFHQVLTICSESIIRVWELETGLQVYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIEVTSAAVDESGFLFATGAYNGTVRIW----DFGSGQEMKVLPEGKDWKEEEH-C
LQRLIFLKAQEKH--QQLVLALERNGTIKMIQGKEDDIYLMVIWELPDVVPFLQDGKH--
-AVHLRMSTRDRNMAIPFPDVELIVERNVSQPP--NNPAMDSLRVNCIDLLQVEG-YNLI
AA----GTLNGVIILWNFVTSTVKEVCRPEDCFPVN-PDLHPKHFKINDILFLFRTPECA
RRSSQDSIC--------------------SSSQCES--SKG--------PQSSKGSKQSI
HDSEVKGEQTD--V------MVGEQQPV-DKKHPGS-ANLPEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKYSAISLTSLYTDSCTRILLAG--NVEGHVILC-NISSFLDPP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---EKQVVLTASIDGS--VRLWHALNGHYCGYF
GQ-----RRLFELSQTSDFILPCDVTEYPIEIKEESKFTE-KQKYEYPLIFDREK-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFKSLSSPKIRRYPLEGFVTENREAGIVFAS
LPIYRIS-SPTSLRFLPLIGVEAQKDSSDGIPGKKKGGHVQ---HEK-----------VS
RRRSLKKNLVPQINLASSFFPAIPK------

-MDSR---DDRQFSLALQINSFKAALVDFDKLVEKTTIQKKEERAGLFIPKEEAIDYEKF
YASVQQIFGPEVKNQDVKCFYRKLCNNPDASFDWCEIFGYFSSDEDSLASHLDEENLVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRVQTNTNVTDTS
WITGCDYLGQLKRIVATTERTIVVWDYKAQGSSQGHYFVIKPMDHCL-------LCVCVV
PIP-DQLCRDDILLGDDGGFVNKFTVNSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANTFC
YCMKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMIYDSNHGMLITGSSVI
DMYPLTRMVQDTKQVPHTHERKINVMLYNRYFHQVLTICSESIIKVWELESGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIELTCAAIDESGYLFTTGAYNGTVKIW----DFGSGQEMKMLPEGKDWVEEEH-G
LLRLFFLKAQVKH--QHLVLALERNGTIKMIQGKEDDVILVVIWELPDAMPYLQYGSH--
-IVHLKMSTKERLMAIPFPDVELIVQKSVTQQT--SNNPAVDVDVNCIDLFQTEG-YNLI
AC----GTLNGMIILWNFVTATVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRPPDCV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKGSRLSI
HDTEFKGEQTDM----------GEQHT-ASRKQAMF-GSSLEAQP-PILVTAHEDGHL--
RLWTLEGKLLKDILPFTKHSAISLTSLYTDFCCRTLLAG--NVEGHVILC-SISSFLDAP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---DKQLVLTASIDGS--VRLWHSTSGHYCGYF
GQ-----RRMFDLSQTSDFILPCDVNEYPVEIKEETKFTEKKQQYEYPLIFDRER-----
---WKKMSSMSLLFKRTPPKPFEVQHDFKFFKSLSSPKIHRYALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDSVDGVHGKKKGAHVQ---HEK------------S
RRKSLKRNLVPQINLASSFFPAITR------

-MDSR---DDRQFSLALQINSFKAALVDFDKLVEKTTIQKKEERAGLFIPKEEAIDYEKF
YASVQQIFGPEVKNQDVKCFYRKLCNNPDASFDWCEIFGYFSSDEDSLASHLDEENLVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQ----------DTS
WITGCDYLGQLKRIVATTERTIVVWDYKAQGSSQGHYFVIKPMDHCL-------LCVCVV
PIP-DQLCRDDILLGDDGGFVNKFTVNSDDFGLKQAKTKKKLQTQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPRGANTFC
YCMKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKE-QHVISLSSA-
---KVFRVWDIQT---------LSVLQVFHDSQGGPGDMQIYSMIYDSNHGMLITGSSVI
DMYPLTRMVQDTKQVPHTHERKINVMLYNRYFHQVLTICSESIIKVWELESGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIELTCAAIDESGYLFTTGAYNGTVKIW----DFGSGQEMKMLPEGKDWVEEEH-G
LLRLFFLKAQVKH--QHLVLALERNGTIKMIQGKEDDVILVVIWELPDAMPYLQYGSH--
-IVHLKMSTKERLMAIPFPDVELIVQKSVTQQT--SNNPAVDVDVNCIDLFQTEG-YNLI
AC----GTLNGMIILWNFVTATVKEIYRPEDCFSTD-PELDPKRFRINDIMFLFRPPDCV
RRSSQDSIC--------------------SSTQCDS--SKG--------PQSSKVSHP--
---PVTSEQTDM----------GEQHT-ASRKQAMF-GSSLEAQP-PILVTAHEDGHL--
RLWTLEGKLLKDILPFTKHSAISLTSLYTDFCCRTLLAG--NVEGHVILC-SISSFLDAP
HDE-KKFKQLLSWRAHSLEIIQVIYVE---DKQLV------------LWHSTSGHYCGYF
GQ-----RRMFDLSQTSDFILPCDVNEYPVEIKEETKFTEKKQQYEYPLIFDRER-----
---WKKMSSMSLLFKRTPPKPFEVQHDFKFFKSLSSPKIHRYALEGFMTENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDSVDGVHGKKKGAHVQ---HEKVKISEK----HMS
RRKSLKRNLVPQINLASSFFPAITR------

------------------------------------------------------------
---------------------------------------------------MDEENLVFL
VSRKQRVVISGSR--RRDVIKCIVKIPQLDLLITASQKGLITVFNSQMRVQTSTKVTDTS
WITGCDYLSQLKRIVATTERTMIVWDYKAQGGGQENYFVIKPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFVNKFTVNSDDFGLKQAKSKKKLQNQVLDSKNF------KS
VKRKLHNDWVMKIRYITALSCFGSCSLDSVHSLVLESLKRLEDNLPVREFSMPRGANTFC
YCTKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSIMEIVMNEKD-QHVISLSSS-
---KVFRVWDIQT---------LSLLQVFHDSHGGPGDMQIYSMVYDSNHGMLITGSSVM
DMYPLTRMVQDTKQVPHTHEREINVMLYNSYFHQVLTICSESIIKVWELETGLQIYQILD
PHGFNVEL

PF00400 // ENSGT00530000063510_2_Domain_4 (549, 577)

TSAAINESGFLFATGACNGTIKIW----DFGSGKKMKMLPEGKDWKEEEH-W
LRHLIFLKAQEKH--QYLILTLERNGKIKMIQGKEDDMYLMVIWELPNVVPFLQDGNH--
-TVYLRTSPKYRSLRIPFPDVEL-VEKNFSQS---VNNPAINMEVNCIDLLQVEG-YNLI
AA----GTLNGAIILWDFVNSTVKELYRPENCFTGD-PDLDPKRFKINDILFLFRTPECA
R-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------

MNTNE---EKREFSVALQMNNFRTALLGFERLVERTAAQKRDERLGLFTQKEDAVDYDKF
YEAVQELFGPEVKNQDVKCFYRKLCNNPDAPMDWCEIFGYFCSEEDVLASQMDEENLIFL
VSRKQRVVISGSR--RRDVVKCIVKIPQLDLLIAASQKGLLTVFNSQ----------DTS
WITGCDYLSQLKRIVATTERTIIVWDYKAQGSSQENYFTIKPMDHCL-------LCVCVV
SLP-DQLCRDDILLGDDGGFVNKFTVNSEDFGLKQAKTKKKLQNQVLDSKNF------KS
VKRKLHNDWVMKIKYLPALNCFGSCSLDSVHSLVLDSLKRLEDNLPVREFSMPRGANTFC
YCVKA

PF00400 // ENSGT00530000063510_2_Domain_1 (366, 382)

NVI-VTGGDDKVLRLW

ENSGT00530000063510_2_Linker_1_2 (382, 387)

HPNIS

PF00400 // ENSGT00530000063510_2_Domain_2 (387, 430)

TKPVGKLVGHMFSITEIVTNEKD-QHVISLSSA-
---KVFRVWDIQT---------LSLLQVFHDSQGGPGDMQIYSMVYDSNHGMLVTGSSVI
DMYPLTRMIQDTKQIPHSHEREINVMLYNKTFHQVLTICSESMIKVWELETG

PF00400 // ENSGT00530000063510_2_Domain_4 (533, 577)

LQIYQILD
PHGFNVELTAASIDEGGCVFATGAYNGTVKIW----DFGSGQEMKVLPEGKDWKEEEH-W
LQDLIFLKPQEKH--QYLILALERNGKIKMIQGKEEDIFLTVIWELPEVVPFLRDGNR--
-VVRLRTSTKSKNTNIPFPDVEVTLERKLSRH---ANNPAVSIDVNCIDLLQLEG-YNLI
AA----GTLNGVIILWNFVTSTVTEVYRPEDCFTVD-PDLDPKRFRINDILFLFRAHECA
RRSSQDSVC--------------------SSSQCDS--SRG--------PQSSKGSKQSI
HDTEVKGQYEITPL------L-HHKNP-VDKKQPGG-SSSAEAQP-PILVTAHEDGHL--
RLWTLEGRLLKDMLPFTKHSAISLTSLYTDSCTRILLAG--NVEGHVILC-SISSFLDPP
HDE-KK

PF00400 // ENSGT00530000063510_2_Domain_8 (967, 1010)

FKQLLSWRAHALEIVQLVYVE---EKQVVLTASTDGS--VRVWQALNGHYCGYF
GQ-----RRIFDLSQTTDFILPCDVSEYPIEIKEESKFTEKKQKYEYPLIFDQQR-----
---WRKMSSMSLLFKRTPPKAFEVEQDFKFFESLSSPKIRRYALEGFITENREAGIVFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDSLDILSGKKKGGRIP---FILQ---------LQG
RRRSLKRHLVPQINLASSFFPSIPK------

-MASR---GGKQYGLALQIHNFRTALVQFEKLIEQTIAQKKDERAGLFIQKEDTIDYEKF
YSSVQQLFGPEVKNQDVKCFYRKLCNNPDASVDWCEIFGYFSSEDDYLSSQMDEENMVFL
VSRKQRIVISGSR--RRDVIKCIVKVPQLDLLITASQKGLITVFNSQ----------DTS
WITGCDYLAQLKRIVATTERTIIVWDYKAQGNSQEHYFVIKPMDHCL-------LCVCVV
PLS-EQLCRDDILLGDDGGFVNRFTVSSDDFGLKQAKNKKKLQMQVLDSKNF------KS
VKRKLHNDWVMKIRYIPALNCFGSCSLDSIHSLVLESLKRLEDNMPVREFAIPRGANTFC
YCVKANVI-VTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVANEKE-QHIISLSSA-
---KVFRVWDIQT---------LSLLQIFHDSQGGPGDMQIYSMVYDVNHGMLITGSTVV
DMYPLTRMIQDTKQVPHTHEREINVMLYNKHFHQVLTICSESIIKVWELETGLQIYQ

PF00400 // ENSGT00530000063510_2_Domain_4 (538, 577)

ILD
PHGFNIELTSAAINESGFLFATGAYNGTIKVW----DFGSGQEMKALLEGKDWREEEH-W
MLRLVFLKAQAKR--QLLILALERSGAIKMIQGKEDDIYLTVIWELPDAVSYLQFWNH--
-TLHLRTVTRDRPMPIPFPDVELILNKSLSQH---ANTPTINSEVNCIALFQTEE-YNLL
AA----GTLNGMIILWNFIAATVKDIHRPEDTFIVD-PDLDPKRFRINDILFLFRSPECT
RRSSQDSVC--------------------SSTQCGS--SKG--------PQSSKGSKQSI
HDSEGKGEQTDK--------Q-AEQNP-ESKRHSVP-ANITEDQP-PILVTAHEDGHL--
RLWTIEGNLLKDILPFTKHSAISLTSLYTDSCSRILLAG--NVGKSLLLD-IQLQ----A
AQP-PKF

PF00400 // ENSGT00530000063510_2_Domain_8 (968, 1009)

KQLLSWRAHSLEIIQVSYVE---DKQLVLTASIDGS--VRLWHSQGGHYCGYF
GQ-----RRMFDLLQTSDFILPCDVSELPVEIKEESKFTEKKQKYEYPLVFDRER-----
---WKKMSSMSLLFKRTPPKAFEVEHNFKFFKSLSSPKSRRYALDGSITENREAGVIFGS
LPIYRVP-SPTSLRFLPLIGSEAQRDSVDVISGKKRGAHVQ---HEK-----------AS
RRKSLKRNLVPQINLASSFFPAMPK------