ENSGT00530000063496_0 : Linker Region Query Results

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KETGDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPLTSDQDEKVSG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPRE-NSSE-DQGSKASENTENRKEADEACNAKS----SSQIPAQPSI--
SKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKE----REREKELEREQEREREKERE--KERERQQEKEKELEREQE
KQRE----LEKERKQEKEKELE-RQQEKEK--ELQKMKE---QE----KECELE---K--
-KEREKVEEKTEHKEPTLEPM----V----------------------------------
---------------------------------EKPESETNCSKEDDAVFTRQDSNRSEK
ETTQVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRREQMEGSPNSSESFEHIARSARDHAISLSEPRVMWGSD
PYPHTEPQQATTP-KAAEEPED--ARPEAPLDQEQI---TAAYPVE---HSQLEVHPKAD
FVRESSETEVQKFLSRSVEDIRPRHTD-TNNQSACFDAPDQKTVATPQEERIAA--GESQ
PARKRSVSHGSNHTQKSEEQRSD-PSASIPKVTSRCVDSKEP-AERTEEKPKKDGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKGE---KVTEKV-VKPEKTEKKDPLPPVPPPAAP----V-QPQSVPPP------
-------PQPELEKLP----PTET--STVVQKPPQDAEKPSEPVGT------VEVEPVAK
TVNQQ--TVTAPAV-KEEKQPEKLGSKDLV-LERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQSSFKPENHIRIDN-RPLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPARPSTLRRPAYRDNQWNPRQAEAPKPD---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTV---NNVVQEPVNPAGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVTKAGENVLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTAVVDTINGNSAHHQ---------
EGTPNGTGQKNTKDSTGKKREDPKSGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQAPGTQQAQAPAPAPAP----APGPAS----------A--AAPAPAP-G-P-
---------------ASAPAPVLTSASAPLPA---SA-------------STPVPPSTS-
---A---TASVSSS--SAPPPTPIL--ASASSPASVP-----ILAS--ASIPILAS----
--ALAPTSASAPAPATSAP--VAPTSA-PAV-----PAP-IPT-----------------
-PVPAPAPTLVPAPASAPAPALVPVPAPPPSAPPQTQGQAHKPGQGPLQT--TTQSSKQP
--PPSVRLPSAQTPNGTDYVATG-KSIQTSQSHGTLPTELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTIDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVAEMSTEIGAMISVSSADYGTNVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSAPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIVSGV--------SSSTSGPSTANYNS
FSSASIPQIPVASVTPTTSLS--GAGTYTTSSLSTKSATTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFTSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAPKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQDQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDENYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKQLG-QDESTA-IPSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKSLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSTSPKE-NSSE-DQTSKAPESTENRKEVDEASSAKSSAQSSAQTPAQPPV--
TKSPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQ-IPGRQGPFPSKP
PVPDNDEIWKQRRKQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKLGIIE
KQPSPEELREREREKE----RERERELEKEKERERE------------------LEKEQE
KQRE----MERARQQ--EKELE-LQREKEQ--ELQRLRE---QE----KEGELK---E--
----QEKEEKLEPQEPVVEPA----T----------------------------------
---------------------------------ENQESENNCKK-EEPVFTRQDSNRSEK
ETTQVVQEAEPESGSQPRP----GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQ--QQQQ
QGVLPQTVPSQPSNGSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLIRRDQMEGSPNSSESFEHIARSARDHGISLSEPRMMWGSD
PYH-AEPQQAAAP-KSAEETGD--ARPETAMDHEHM---TAAYPVE---HSQLETHSKTD
VARDSTETEGQKFLSRSLEDVKPHHVD-TNNQSACFDVIDQKSLPTPTEERISA--LESQ
PARKRSVSHGSNHAQNAEEQRNE-PPVSIPKVTNRCMDSKET-VEKPEEKPRKDGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KVTEKV-VKAEKPEKKDLPLPLPPPAPA----Q-PQPLVSPP------
-------VQPE-EKPP----STET--STLTQKPSQD-EKPLEPVGS------VQAEPVVK
TVNQQ--SVAAPIV-KEEKPPEKVINKDVG-IERPRPDSRP---------AVKKESPL-P
TRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEQVP-SGPLRRREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKREERSENKKPV-KPQSSFKPENHVRIDN-RPLEKPYIRDE--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPATLRRPAYRDNQWNTRQAEPPKPE---DGEPP
RRHEQFMPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-LVPSNGTA---NNVVQEPVNPPVDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADMSS-----QAVVKAGESVLPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKGGKRGPFDDQASGTAAVDSVSGNSVHHQ---------
EGVPNGAGQKNSKDAAAKKREDAKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVVQVWSKKNIGEK----GR-SQTSK
LPPRFAKKQATGTQQTQAPP----S----APVLVSS--SAPVLTPA--ATTVPAS-T-P-
-APVPILASATTLVPVSTPAPVLTSCPAPVPT---SA-------------SAPVPASTSS
PVMA---S-SSSQP--PVPAPTPIL--ASASTTVSVP-----ILTS--ASIPILAS----
--ALAPATVSSPSPVVSAT--AVPSISTPAI-----PAS-A----PTASVPLAPASAAST
--------------------------APPPASTVQTQTQTHKPVQSPLPP--SAPSSKQP
--PPSIRLPSAQTSNTTDFVTAG-KSMPTSQPHGSLTAELWDNKVAAPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKPTDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEQPSPAVVRSADPGTAKETKAVSEMSAEIGAMISVSSPEYSSDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNLREKGSPVTSTAPPIVSGV--------SSSASGPSTANYSS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSIQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPQLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMMATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMAQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLXSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DLKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KTQRVXX-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXLFI

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKTLETQKAAVTARHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNINIVPKDGTGWASKPEQQEEEKPPEVPQ-TEPKPAVPAPPEAPP
VAKSWANTKQGGQGDG-PGVQINSYFQQEFPSLQAAGDQEKTNKDKDAAEEPYGPGPSLR
PQ-NVASWREGGGKNLNSPNAPPDEEAKPLTQEDGSVV-APTEQNDGLKIPEK---R-ET
-RVIQPPQPKLNG-QQPGLISQYRAIIPPY---MFNQYPKLAYP-QMPGPSRFPTP-SEP
SRGLRGRGP-SSRSSEAVERPSILSANELKELDKFDNLDAEADEGWAGAQSEVDYSEQLN
FSDDDEQGSNQKEHHNSNEPTK---DLEEKNGEH--------KS------S--LTLQSIG
TKGPCNQSCPSDQQGQV----SSSMLERGTTGLHSKSVLQPPVPDRLTGSGRQGPFPPR-
SAADEDEIWKQRRRQQAEISSAVERARKRREEEERRMEEQRKAACAEKLKKLNEKFGCVA
KPPREDPFKEKEKVKEKEIEDERRKANEKEIGEVVPIE----RKEEESQKKEKEPEREPE
KEKE----------PERETEM-------------E-------------KESEREEKEI--
-SEEKPIPELSEPQEPVTLPLKVEKP----------------------------------
---------------------------------EENETNTDEGRECQAVSATQESNHNER
---ESFHESETDSGAHTRPALSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQ--------Q
QGVMPQSTP-QPSGSPVPPPAHRPLYQPMQPHPPHLASVGFDPRWLMMQSYVDPRIISGR
PAMEMPPMHPG--IITPKPLLRRDQVEGAGTGSDSFDHVTRPARENTIPQSEPHMMWGSD
SYPHTEPPETSALPNLLEESEDTR--PRAVLDQEQMPI-----QVVYSEQSQLDSHTKTD
CFKEPGKVNVPKSSEE-----PSCQTD-TLTPSIDFEATVENVLQISQEEQVSK--EENN
SFPRKSFSYESSHSLKSEEQDID-ILANVIKANSRHIEPKEAIVERVDNKLKKEGFTSN-
--RLSEGPKLEKPFKPKSETRWGPRPGYGRREDGSDRPVRRSGPIKKPILRDMKEEREQR
EEREQKRERGGGKLTNERFNKNEKREQAPLPSLRLEPEKTITGDKKALQGTPQTSESANS
SMESGTTVAPSGQQSPVVQESTV--IAPVVQHPT-TTQAPPPAVPQP-PSPQIAVEPPSL
TVQQL-PVHHSVNAVKEEKQPEKVINKEKP-AERPHIETRP---------VKRE--SGLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHNRDYPHYRDPKP
RVEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDSDSEVHES--DTLLSDKDS
LSKSKHPKRDEKADVKKPA-KTLLSFKPENNVQEES-RILDKTYGKDD-ENKPKPGFLPK
GEPSRFGRG--GMFRRGSREPVSRPSRASTLRKPGYRENQWNSRQTEITKAE---DIDSQ
GRHGHCGSIPLDKRQPIKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKIN
EATTSSSSSAVV---SNALSEQPNTTLDVSGIKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKLADVMA-----QVTVKAGESTLTPKREIAKRSFSSQRPGIDRQNRRG-NSG
PPKSGRNFSGPRNDRRS-GPPTRSGKKGPFEEQTPVMINAELVNNS-LHQE---------
ES---TAALKGSKDSNNKKREEPKAGPKKPKEKVDAISQFDLNNYASVVIIDDHPEVTVV
EDSQSNLNNDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKSSNEK----GR-CSNSK
LPPRFAKKQQQAAAAAAAAAQQVQAQP---------------------------------
------------------------------------------------------------
-------------------QPQ--------------------------PQIPLQCV----
--------SQVP--------------------------------SPQ-------------
------------------------------------------------------------
--------ATCPVSNSTEYTAIS-KSLQDT--SSHVGTELWDNKVPATTVLGD------I
SKKLGPISPPQPPSVSAWNKPLTSFGSPTSSEGTTAGQESGNDLGIETIQFGAPASSGSD
NEVGPV-SEKPSEKLLEPKEQRQKQPRAGPIKAQKLPDMSPVENKEYKPGPIGKERSLKN
KKVKEAQQ-GNCEVQEKSSPPTVQSPEPIPSKETSAAAELGTEMGTMMSVSAPEFEA---
------------------------------------------------------------
---AQKMESARKAWENSPNVTEKNSPVTSAASPVTGGNSSGSGVGNSNSSSGPTSGTYSS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKTTTTSDPPNICKVKPQQLQTS-NL
TSASHFSQLNCMPSLIAQQQQSQQVYVSQSAA---AQIPAFYMDTSHIFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQTQELFNSSLQPYRS
QQAFMQSGLSQPSPVVLSGTTLHNFPTVQHQELAKAQTTLAFQQTSNTQPIPILYEHQLG
QPSALGGSQLIDTHLLQARATLTQASNLYSGQVQQPGQTSFYNTAQSPSALQQ-----VT
VPIPGSQLSLPNFAS-AGQPLIALPQSLQPPLQHTAPQPQPQSLGRPSQVGQPFRGLIPA
GTQHNII--TGKMSEMDLKAYGSVID--KPGTPPVSGRSTTPTSSPF-RAASTSPNNQSN
KMNTIIYQK-QFQSA--AVRMAQ-PFPPQFTPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PVALVSQMPHQMTTGLLSHP-----------RLPHVARGPCGSLSGVRGNQAQAAMKAEQ
DIKAKQRAEVLQSTQRFFSEQQQS---KPTGG-KIQKVLD-DGNKGPEGASDSSTVCQDK
VDEKPNPAPTA-------ASKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNAKS----SSQIPAQPSV--
AKVPFGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQE--KEKE-RQKEKEK--ELQKIKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIPKVTSRCIDSKEP-TERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KVTEKVVIKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKSLEPVST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AIKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPM-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKIGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAAVP-------
ATLTPVLASTSAPVPASTLVPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
VAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPLAPASA---
---------------PAPATTPVSAPTSAPPAPAQTQTQTHKPVQNPLQT--PSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKEAKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKKRAVGRGL
SHKTFGPRCWQSREQRFFSPRNG--S-SLN-SNRANR-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYTTLSLFNTYKGKSLETQKTTVAARHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKPPEVPP-AQPKSGITAPPEVPP
VAKSWASNKQGGQG------DVNSHFQQEFPSLQAAGDQEKKE--KDANDDAYGPGPSLR
PP-NVASWREGGKSAG--PSSPSDQEDKLPG-QDDGAN-GPVEQNDSHKTTEK---R-LP
GVPPQIPQPKLNGQQQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPIRFPPSLSEA
NKGLRGRGPPPTWAPEP-ERPSILSATELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGGSQKDNKDNCE-E-APKTSESAENRKDDDEGSGPKSQ--------LLPQSSV
SKGPYGKGPPF-NQSLMHEKNSTAHLPL---QPKTLTQQHPP-PDRQAGPGRSGPFPPK-
QVPDEDEAWKQRRRQPSELSAAVERARKRREEEERRMEEQRKAACAEKLKQLNEKYGIPT
VQPVLDKQENESCNKEKID----------------------------------FLKRLPH
TSFL-I--LTI--SISSFQLLGIFLRKKFINNKLERLSG-------FSWKCDFY---K--
---TYNLSSSILPRSYGVNKFT---E----------------------------------
---------------------------------MGMKNNYFILSEEQPVFTRQDSNRSEK
E-PQVTHEVEPDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQSAPSQPSSGAVPPPPHRTLYQPMQPHPQHLASMGFDPRWLMVQSYMDPRMMSGR
PAMDIPPIHPGIRMMPPKPLMRRDQIESSTASSESFEHIARSARDHAVSLTEPRMMWGSE
PYPQVEPQQASSPPKLAEEPKD--LRPEAPLEQELM----PSYTVE---HSQLDTHPKAD
FFRDAGETEVQKFPNKSLEDTRPPPTD-TNSQTACFEVGDQNVVPTPQDDQSPV--GDGQ
SARKRSVSHGSSHSQKSEEPRNE-VPANIPKVNNRCIDTKEP-PERLEDKPKKEGFI---
--RPSEGPKLEKLYKSKSETRWGPRPSSSRRDEGGDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKVE---KPTEK-VVKPEKPEKKDPPPPPAA-------QV-QPQPLPPS------
-------HPPEPEKPP----SETS---SLAKKPSQDNVKSPETIDS------VHIEPAIK
TSNQQ--TAPLHVT-KEEKQPERVIGKEQGIVERPRIDTRP---------VKKE--PILP
PRTYWKESRERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHNRDYPHYRETKP
RTEHVP-SGSLRQREESETRSESSDFEIVPKRRRQRGSETDSDSEVHESASDTLPSDKDS
LSKGKHPKREERPENKKPL-KPLLSFKPENNVRVDNNRPLEKLYVRDD-ENKTKPGFLPK
GEPTRRGRG--GMFRRGGRDPGGRPPRPSTLRRPTYRDNQWNPRQAEPPKPD---DGEPL
RRHDQFIPIPADKR-PPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKIN
AVATTSATNGTI---NNVVQEPVSASGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADLSA-----QATAKVGENALPPKREIAKRSFSSQRPGIDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPSSKSGKRGPFEESSVGMAGVDPANGSSVHHQ---------
DGGPNGTGQKNPKDVSGKKREEPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTIQVWNKKTSNEK----GR-NQNSK
LPPRFAKKQQQAAVGQQPQTATPPP-----------------------------------
---------------------VQGLAQA--------------------------------
-------------------------------------------------QVPA-------
-------Q----------------------------------------------------
---------------------------------VQTQTTTQNPNQ------------SPP
--SVQSQVQTTNATNGTDYVATG-KSIQHTQSHGPLGAELWENKVAPTPVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSSTSPEGTKNGQESGVEIGIDSIQFGAPASNGNE
NEVIPVLTEKPPDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDVQQ-AEPEGQEKSSPPSVRNPDAVTTKETKTVTEMSSEIGTMISVTAPEFGANAK
ESVTDYTTPSSSLPNTVATSNTKMEETLVTNVPL-PNTLPLPKRETLQQSSSLTPAPPTT
FNLTFKMESARKAWENSPNVREKGSPATSTAAPIASGA--------GSSASVPSTGNYNS
FSSASVPPIPVASVTPTTSLS---AGTYTTSSSSTKSA-TTDPPNICKVKPQQLQTS-SL
PSASHLSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPAS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFNSPLQPYRS
QQAFMQSSLSQPSPVVLSGTTLHNFPAVQHQELAKAQSGIAFQQTSNAQPIPILYEHQLG
QASGLGGSQLIDTHLLQARASLTQASNLYSGQVQQPGQSSFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTPPQPQAQGLNRPTQVNQPFRGLIPA
GTQHSMIAATGKMSEMDLKAFGSGID-VKPGTPPIGGRSTTPTSSPF-RASSTSPNSQSS
KMNSIVYQK-QFQSTAATVRMTQ-PFPAQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSNKTPETLTDPPGVCQDR
VEDKPPPTPTT-------AAKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPSTSDQDEKLPG-QDESTA-GSSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENTETRKEADEGSNTKS----SSQIPTQPPV--
AKGPYGKGLPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKLGIVD
KQPSPEEIREREREKE----REREKELEKEQER----ERE--KERERQQEKERELEREQE
KQRE----MEKEKKQEKEKELE-RQQEKERELELQKPKE---QE----KEWELD---K--
-KEREKVEEKIEHKEPALEPV----V----------------------------------
---------------------------------EKTEN-ENCNKEDDPVFTRQDSNRSEK
ETTQVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQAVPSQPSGAAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSANSSESFEHIARSARDHAVSLSEPRMMWGSE
AYPHTEPQQATAP-KTAEEPEG--VRSEATLDQEPT---TAAYPVE---HSQLEAHPKAD
FVRESGEAEVQKVLSRSVEDIKPPHSD-TVSQSACFDVPDQKTIPTPQEERISS--GENQ
PARKRSVSHGSNHTQKSEEQRNE-TSASIPKVTSRGIDSKEP-AERSEEKPKKDGFL---
--RSSEGPKPEKLYKSKSETRWGPRPSSSRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVIEK-VVKPEKTEKKDPLSPPPLPAA----PV-QPQAVPPP------
-------PQPEPEKSP----STET--PTLVQKPPPDTEKPLEPVSS------AEVEPATK
TVNQT--V-TAPTV-KEEKQPEKVVSKDLV-TERPRSDLRP---------VIKKESTQ-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTREYPQYRDTKP
RTEHVP-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
SSKGKLPKREDRSENKKPI-KPQSSFKPENHVRIDN-RPLDKPYIRDD--DRSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRENQWNPRQAEAPKPD---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPTRERPRRQRPTRPPRQDKPPRFRRLREREAVSKTN
E-V-AVPTNGTV---SNVVQEPVSTAGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QATAKAGETVSAPKREIAKRSFSSQRPGVDRQNRRG-NGG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTTGVDPVNGSSAHHQ---------
EGTPNGTGQKNSKDSAGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNASEK----GR-SQTSK
LPPRFAKKQSTGTQQAQSPAPAPAPGP------TSTLPSGPVL-----------------
-------ASPSA--TAVSAAPVLTSTSTPLPT---PASA-------------PTPAST--
--------SAPTSS--SVPAPTPILA--SASNPAAVP-----ILAS--ASIPILAS----
--ALPPTSATPPASSA--P--TVPASSAPTA-----PA----------------------
----------IPTPVSLPTPALVTVTIPGPTAPAQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTSQSHGTLTTELWDNKVAPPTVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKT-DKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPAAVRSVDPGTAKETKAASEMSTEIGTMISVSSTEYATNVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSSANYNS
FSNASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPTFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQNSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSSTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSTLQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTAPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIPTTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMSSIVYQK-QFPSAPATVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAPKVDG-DSSKPPEALTDAPGVCQEK
VEEKPPPAPTM-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETSDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWAFEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNAK-----SSQIPAQLSV--
AKVPCGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSSRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVREASEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLSAPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIPKVTSRCIDSKEP-TERSEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KVTEKVVVKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKSPEPVST------VQVEPTVK
TVNQQ--TMAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHIP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKAKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NSVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSEKQQKRLQDR----REETVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASIPPLASAPLPPSTSASVPAST------SAPLP-------
ATLTPVPASTSAPVPASTLAPILASTSAAVPA---SPLAPV---STSASVSSSVPASTSA
AAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ALSPILAS----
--ALAPTSAPTPAAAASSP--AAPVITAPAV-----PAS-A----PTVSVPLVPASASA-
---------------PAPAPTPVSAPNPAPPPLAQTQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPS-GLLLQVRTASPA
K-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAPPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDSYGPGPSLR
PP-NVACWRDGGKSAG--PSSSSDQDEKLVG-QDENTT-ITSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQAPLGSQYRAMMPPY---MFQQYPRMAYP-PLHGPVRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSTKASENTENRKEPDEVSNTKS----SSQTPAQPPV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLVQQHPP-PDRQGIPGRSGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKFGIVE
KQPSPEEIREREREKE----REREKELEKEQEQ--------------------ELEKEQE
KQRE----VEKERKQEKEKELE-RQREKEK--ELQKMKE---QE----KECDLK---K--
--EREKVEGKIEPKEPVLELV----T----------------------------------
---------------------------------EKQENEKGCSKEEEPVFTRQDSNRSEK
ETTQVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ-------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPSNSESFEHIARSARDHAVSLPEPRMMWGSD
PYPHAEPQQAPTP-KTNEETED--VRPEAALDQEQI---TAAYPVE---HSQLETHPKAD
FVRESSETEVQKFLSRSVEDIRPHT-D-TNNHSACFEVPDQKTLSSTPEEQISA--LESQ
PARKRSVSHGSNLSQKSEEQRNE-PSVSLPKVTSRCIDSKEP-AERPEEKPRKDSFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KATEKV-VKPEKTEKKDLVSPPSPPAAP----V-QPPSVPAS------
-------VQPEPEKFP----STEP--STLAQKPSQDTEKPLEPVSS------VQVEPAVK
TVNQQ--TAPSPAV-KEEKQPEKAISKDAA-IERTRTDSRP---------AVKKEPTL-P
PRPYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-STPLRQREESETRSESSDFEVMPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKRDEWSENKKPL-KPQSSFKPENHVRMDH-RPLEKPYVRED--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPPYRDNQWNPRQTEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAATKTN
E-V-SLPTNGTV---HNAVQEPANTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERREREEKKNADLNA-----QAVVKAGENVLPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSVGPTCVDPINSSSAHHQ---------
EGAPNGTGQKSSKDSAGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNTNEK----GR-SQTSK
LPPRFAKKQATGTQQAQAPVSALVSAPVP------SSTSALVLASP--GTPVPA------
STATVVVTSPAVLVSAPTQAPVLPASSVPGPA---SPSAP-------------VPSSTSA
P-TT---ASSSASA--STPAPTPIL--ASASTPVSVP-----ILAP--ASIPILAS----
--ALAPASAPPPATAVAAP--AASASV------------------SAASVSLASASA---
-------------------SAPTPTPASAPTVPAQTQAQTHKPVQSPLQT--S-QASKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQSHGSLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKS-DKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPAPAPVRSTDSVTAKETKAVSEMSAEIGTMISVSSAEYASDAK
ESVTDYTTPSSSLPNTVATNNAKMEDALVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPLASGV--------SSSGSGPNAASYSS
FSSASVPQIPVASVTPTTPLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPPVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSTPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPSETLTDPPGVCQEK
VEEKPPPASTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVVPPPEAAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--PSSSSDQDEKLLG-QDENTA-ITSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQVPLASQYRAMMPPY---MFQQYPRMAYP-PLHGPVRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSTKASENIENRKEADEISNTKS----SSQTPAQPPA--
AKGPYGKGPPF-NQERG---PPSSHLPP---PPKLLAQQHPP-PDRQGIPGRSGPFPPKQ
QAPDEVEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKFGIVE
KQPSPEEIREREKEKE----REREKELEKEQEQEREKERE--RERQQE----KELEK-EE
KQRE----MEKERKQEKEKELE-RQREKEK--ELQKIEE----E----KECDLK---K--
--EK--------------------------------------------------------
---------------------------------------------EKPVFTRQDSNRTEK
ETTQVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPSNSESFEHIARSARDHSVSLPEPRVMWGSD
PYPHAEPQQAATP-KTNEESEG--VRPEAALDQEQI---TAAYPVK---HSQLETHPKAD
FVRESSETEVQKFLSRSVEDIRPHN-D-TNKQSTCFEVPDQKTLSSTPEEQIST--LESQ
PARKRSVSHGSNLSQKSEEQRNE-PSISLPKVTSRCIDSKEP-AERPEEKPRKDSFI---
--RSSEGPKPEKIYKSKSETRWGPRPISNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KATEKV-VKPEKVEKKDLVSPPSPPAAP----V-QPPSVPAP------
-------VQPEQEKFP----STEP--SALAQKLSQDTEKPLEPVSG------VQVEPAVK
TVNQQ--TAASPAV-KEEKQPEKVIIKDAG-IERTRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-STPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKRDERSENKKPL-KPQSFFKPENHVRMDN-RPLEKPFVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPTRPPTLRRPAYRDNQWNPRPIEAPKPE---DAEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAATKTN
E-V-SLPTNGTV---HNVVQEPANTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QALVKAGENVLPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSVGPAGVDPVNGSSAHHQ---------
EGATNGTGQKNSKDSTGKKREDTKPGPKKPKEKIDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKTTNEK----GR-SQTSK
LPPRFAKKQATGTQQAQAPVSALSS----APVP--SSTSALVLASP--ATPVPAS-S-A-
---AVVATSPTVLVSAPTQAPVLPATSVPVAA---SLSA-------------PVPSSTS-
APTA---ASSSASA--STPTPTPIL--ASASTTTSGP-----ILAP--ASIPILAS----
--ALAPASAPPPATAVSAP--TVPAISAPAV-----SA----------------------
---------------------------------SVSAAQTHKPVQSPLQT--S-QASKQP
--PPSIRLPPAQTPNGTDYVATG-KSIQTPQSHGSLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQDSGVEMSIDTIQFGAPASNGNE
NEVVPVLSEKSTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPTPTAVRSTDSVTAKETKAVSEISAEIGTMISVSSAEYAADAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPVASGV--------SSSASGPSPANYSS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSTPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPASAI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQ--------GIQVNSQFQQEFPSLQAAGDQ---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNAKS----SSQIPAQPSV--
AKVPFGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQE--KEKE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIPKVTSRCIDSKEP-TERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KVTEKVVIKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKSLEPVST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AIKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPM-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKIGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAAVP-------
ATLTPVLASTSAPVPASTLVPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
VAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPLAPASA---
---------------PAPATTPVSAPTSAPPVPAQTQTQTHKPVQNPLQT--PSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKAKQRAEVL
Q-----------STQRFFSEQQQ--S-KQI-GGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTXXXXXXXXXXXXXXXXXXXXPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQDQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKPAG----SPSEQDEKTPG-QDDSTP-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPSY---MFQQYPRLAYPPTAHGPMRFPPSLSDT
NKGLRGRGPPPLWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKSSENTENHKEADDTNSTKS----SSQIPAQPLV--
AKGPYGKGPPF-NQDHG----PSSQLPP---PPKLLTQQHPPPPDRQAGPARGGPFPAKQ
QVPDEDEIWKQRRRQQSEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGIVE
KQPSPEEIREKEREKQRE----REKELEKEQEREREKE--KERERERQQEREKELEKEQE
KQREVEKE-----KQEKEKELK-----------EQKVKEEEPKTSEQETDCEPE------
-QGEKNVERQVEPRLCFXXXXX-XXX----------------------------------
---------------------------------XXXXXXXXXXXXXXXXXXXXXXX--XX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQMKQQQWQQQ------QQ
QGVLPQTVSSQPSSSAVPPAPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMNPRMMSGR
PAMDIAPIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXPEAP--LEQM---TPVYPIE---HSPLESHPKAD
FLRESNETEVQKFLSKSVEDIRPHHTD-PNNLSSCAEVADQKVISTAQEERTSA--AESQ
PVRKRSVSHGSNHTQKPEEQRNE-PFVSIPKINSRCIDSKES-TERTEEKPKKDGFM---
--RSSEGPKPEKLYKSKSETRWGPRPGSNRRDEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGT------EK-VVRPEKPEKKDPLPLPAPAP----APV-QSQSVPPP------
-------PQPEPEKPP----STEP--STLPQKPPPDTEKPAETLNS------VQVEPTVK
TVNQP--TVSVPTV-KEEKPPEKVITKDLV-IERPRPDTRP---------AVRKESTLQA
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDTKP
RPEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DRDS
FSKGKLAKREERSESKRPI-KSHSSFKTENHVGIDNRXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX--XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XX--XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXKNADLAQ-----TSV----SENALPKREIAKRSFSSQRPGVDRQNRRT-NNG
PPKSGRNFSGPRNERRN-GPPAKSGKRGAFDDQSSGTTGVDPHNGGSAHHQ---------
EGAPNGTGQKNSKD-TGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNINEK----GR-NQTSK
LPPRFAKKQTTGTQQTPVPASASPSTTVPGSTS------APVL----------------S
SNSTPIVASTLASVPPSTSAPVLVSASAPVPT---SA-----------SPLSPVPASTSA
IA----TASSSVPA--PGPAPTPILA--SVSAPATVP-----ILAS--APIPILAS----
--ALAPASTPAPAPTVSAP--TASTVSAPSA-----TTS-I---------PLTPTSAPTP
S-----------------------------TAQAQVRAQTPKQVPIPLQL-----SKTGH
--PLSIRLPFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSKAAPPAVLND------I
PKNLGPISPPQPPSVSAWNKPLTSFGTATSPEGPKNGQESGVEIGIETIQFGAPASNGNE
NEVVPVLSDKTTDKIAEPKEQRQKQPRAGPIKAQKLPDLSPVESKEHKPGPIGKERSLKN
RKVKDIQQ-VEPEGQEKPSPATGRSTDPAPTKETKAVPEMSTEIGTMISVSSTEFGTSAK
ESVTDYTTPSSSLPNTVATNNAKMEDSLVNNVPL-PNTLSLPKRETIQQSSSLTSVPPTT
FSLTFKXXXXXXXWENSPNVREKASPVTSTAPPIASGVS-----SA-----SGQSTNYNS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA--XXXXXXXXXXXXXXXXXXXXXXX-XX
XXXXXXXXXXXXXXXXXXXXXXXIYAPLQDEH-ARLSLGAGPAVSQAQELFSSSLQPYRS
QPTFMQSSLSQPS-MVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLS
QASGLGGSQLIDTHIL-ARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TGQPLIALPQTLQPPLQHTTAQPQAQSLSRPAPVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSSID-IKPGTPPISGRSTTPTSSPSGLLPRVRTVSPAK
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPDVPQ-TQPKPAVPAPPEAAP
VAKSWANTKPGGQDG--PPIPINSYFQQEFPSLPAAGDQEKSGKDKDAPE--DGSGTNLR
PQ-NATSWRDEGNKNH-SGS-PTDQ--EAKG-QEDGST-TPAEQNDGQKAGDK---R-DV
-RLPQIPQPKLNGQQQPPISSQYRAMMPPY---MFNQYPRMAYPPSMQGPTRFPNS--EP
SRGPRGRGP-PSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLN
FSDDDEQGSSQKEKESG-DEQTPAKDSQSPDGQKETEEQTNAKSATQ--------VSTAA
AKGSYSKSSQL-DQVSGEASHFPPAP------RKSYFQAHPPPPDRQ--MGRQGPFPPK-
PVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCVT
KPSREDPLKDREREREREREREREREREREKEREREREREKEREKEKEKEREREKEKEKE
EKEKL----EKAKEQE---------------VEKEKEKEVEKEEKENEK-------EK--
-EEEKPAHEVPEPVEPVAAPVV-EKQ----------------------------------
---------------------------------ESETKNNKE---EKAVFTRQDSGRNEK
EVSQVTHENEPDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ-------Q
QGVLPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDMPPIHPG--IMPPKPLMRREQLEGSAAGSDSFEHMARSAREHSVPLSEPRMMWGSE
PYPHAESQQSTSPPKVLEEPDDLRSEAH--LEQERVAVPASAYPVE---HNQLDSHPKTE
FFRESGEVEIQKFPSRPLEDVQPLQTD-TANTAVNFEGVSEKVTRSSPEELVPV--GENH
SSLKRSISHGSSHSLKSEDQRSD-TAANIPKLSNRPIETKET-IERLEIKPKKEILITN-
--RTSEGPKPEKTFKPKSETRWGPRPGYGRRDEGGDRPVRRSGPIKKPVLRDMKEEREQR
EEREQRKEKEGEKTATEKPGKPEKSDKKESPQVPQSQAEPERSNS-SSTPLAKK------
-------INQDAAPA------------PASQESSQ----PEAAAKA--------VVQPPA
PAVQQ--QLPAAQPATDDKQAEKVVSKEVV--EKPRLETRP---------VKRE--PGLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGTRGHNREYPHYRDSKP
RSEHVP-SGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDS
IIKGKHPKREERADGKKPP-KPL-SFKPENNIRVDN-RSLEKTYIRDY-ENKPKPGFLPK
GEPSRRGRG--GMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKPE---DGEPP
RRNEHYGPIPIDKR-PPKFERKFDPNRERPRRQRPARPPRQDKPPRFRRLKEREAASKIS
EVVTSSTTSATV---NNAVSEPSNPALDVSGSKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADAAA-----QVAAKAGENAGAPKREIAKRSFSSQRPGIDRQNRRG-NNG
PAKPGRNFSGPRSERRS-GPPPRSGKRGPFEEQAAPVPGVDPTNGNSVHQE---------
DGGVTAAGQKATKDASSKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVQDQHVGEKLLAVLGLLSRVQK
LPSKN---FLLLNITAYCSYLVNKINFYLVTLAFNT-----SQLGSVRQVELATD-KNTV
FHTVIKIYLIACISVDSKKKMGEK---S--L-----F-V--------L-L-N--T--P--
P-------K--T----I-D--V-K----A-G-LI-S------LLF---AFC---------
--TLQ-LL-SVHI-VTWKN--K-IVFS-LQ------VW--T-K-K--G-S--S-------
---------EKGRGQNSKLPPRFAKKQQQAAAAAAQQAQ------AQAQPPCPAQSPAQP
QAPVPAQSQAAGGTASTDYTVSG-KVLQNSQPHNSLGAELWDNKVPPTAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSSPSPEGTKPGQEGGVDLGIETIQFGAPASSGSD
NEVGPVLSEKSTDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKN
RKVKDAQQ-GEPEGQEKPSPTSVRSPEPVTTKETKAASELSTEIGTMISVSAPEFGTNTK
ESVTDYTTPS-SHPNTVATSSTKMEETLVTNVPL-PHTLPLPRRETLQQSSSLTPVSPAT
VDLTLKMESARKAWENSPTMGEKNSPVTSAASPIAGGGG------SSSSNTGPSSGTYSS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTS-SL
ASASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFSSSLQPYRS
QQAFMQSGLSQPSPVVLSGTALHNFPAVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQ-----VT
VPLPGSQISLPNFGS-TAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPA
GTQHSMIAATGKISEMDLKAFGGGID-VKPGTPPVTGRSTTPTSSP--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQ-TQPKPAVPAPPEAAP
VAKSWANTKPGGQDG--PALPVNSYFQQEFPSLPAAGDQEKSG--KDKDASEEAHGPSLR
PQ-NQ--------------------DAKALG-QEDGNA-TPAEQSDGQKAAEK---R-DV
-RLPQIPQPKMNGQQQPPISSQ--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------YRHPPPPDRQLGPGRQGPFPPK-
PVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMT
KPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKE
EKEK----LEKAKEQEREKEKE---------N--EREKE----EKEREKE-------K--
-EEEKPVHEAPEPVEPVVTPAV-EKQ----------------------------------
---------------------------------ESESRNNKEEKEDQAVFTRQDSGRNEK
EISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQQQGGFSGP
PDILCF--------------------------------MG--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGMQVNSHFQQEFPSLQAAGDQEKKE--KETSDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPLTSDQDEKLSA-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-SSSE-DQGSKASENTENRKEADEARNAQS----SSQIPAQPSL--
SKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPAKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPPPEEMRDRERDKE----REREKELEREQEREREKERE--RERERQQEKERELEREQE
KQRE----LEKERKQEKEKELE-RQQEKEK--ELQKIKE---QE----KECELE---K--
-KEREKVEEKTEHKEPTLEPV----V----------------------------------
---------------------------------EKPESETNCSKEDDAVFTRQDSSRGEK
ETTQVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ-------QQ
QGVLPQPVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRREQMEGSANSSESFEHIARSARDHAVSLSEPRVMWGSD
PYPHTEPPQATTP-KATEEPED--ARSEAPRDQEQV---TAAYPVE---HSQLEVHPKAD
FVRESSETEAQKFLSRSVEDVRPRHTD-TNTQSACFDIPDQKTIGTPQEERISA--GESL
PARKRSVSHGSNHTSKSEEQRND-PSASIPKVTSRCLDSKEP-AERTEEKPKKDGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEKV-VKPEKTEKKDPLPPVPPPAAP----A-QPQSVPPP------
-------PQPELEKLP----SAEA--SAVVQKPPQDAEKPSEPVSS------VEVEPVAK
TVNQP--TVPAPAV-KEEKQPEKLGSKDLV-LERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHARDYPQYRDSKP
RPEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQSSFKPENHIRVDN-RPLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPARPSTLRRPAYRDNQWNPRQTEAPKPD---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTSSTV---NNVVQEPVNPAGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVTKAGENVLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTAVVDPVNGSSAHHQ---------
EGTPNGTGQKNAKDSTGKKREDPKSGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQAPAPAPASASA----PA----------------------------
------LASASAL--APAAAPVLTSASAPLPT---SA-------------STPLPPSTSA
--------AATVSS--SAPAPSPVL--TSASSPASVP-----ILAS--ASVPILAS----
--ALAPASASAPAPAASAP--GAPAPAAPAP---------V------------------A
TPTPAPAPALVAAPA--SAPALVPVPAPAPGAPAQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTSQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAAPSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-AEPEGQEKPSPAAVRSTDPVTTKESKAVAEMSTEIGAMISVSSTEYGADVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PSTLPLPKRETIQQSTGLTSAPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSAGGPSAANYSS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAPLNLGAGPAVSQAQELFTSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFPSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAPKVDS-DSSKPPETLADPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKITVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSA-AQPKPGVAPSPEVAP
APKSWASNKQ--------GIQVNSHFQQEFPSLQAAGDQ---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-VTSEQNDILRVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMIKIL---YF-------------------------
FPGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNTKS----SSQIPAQPPV--
AKGPYGKGPPF-NQERG---T-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREKEREKE----REREKELEKEQEQEREKERE--KERERQQEKEKELEKEQE
KQRE----MEKERKQEKDRELE-RQKEKEK--ELQKIKE---QG----KECELE---K--
--EREKLEEKIEPREPNLEPT----A----------------------------------
---------------------------------EKQESENSCNKEEEPIFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDISPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--IRPEAALDQEQI---TAAYSVE---HNQLEVHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-TSNQSGCFEVPDQKTLSTPQEERISA--GESQ
PSRKRSVSHGSNHTQKPDDQRNE-PSASIPKVTSRCIDSKEP-TERPEEKQKKEGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKTEKKDLLPPAPPPQPPAP--I-QPQSVPPP------
-------IQSEAEKVP----SPET--ATVAQKPSQDTEKSLEPVSS------VQVEPAVK
TVNQQ--TMAAPIV-KEEKQPEKVISKDLV-IERPRPDSRA---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKSI-KPQ-SFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPPYRDNQWNPRQSEIPKPE---DGEPP
RRHEQYIPLAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKSGKRGPFDDQSAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSPSVPPLASAPLPPSTLASVSAS----T--SAPVPA------
-TLTPVPASTSTPVTASTLAPVLASTSAPVQA---LPLAPV---SASASVSASVPASTSA
AA-I---TSSSAPA--SAPAPTPIL--ASVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPIITAPTV-----PAS-A----PAASVPLVPASASTP
APAPT----------------PVSASAPAPTAPAQTQAQTHKPVQNPLQT--ISQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLLEKSTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKASPAAVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNSK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSTSGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQPQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-MKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSG
KMNSIVYQK-QFQSAPASVRMTQ-PFPTQFA-----------------------------
------------------------------------------------------------
----KQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKMGQ-KARPP--------GPIRQV
VNAKDKS-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVVAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GASEQNDILRVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASESNENKKEADEVSNIKS----SSQIPAQPPV--
AKGPYGKGPPF-NQERG---T-SSHLPP---PPKLLAQQHPP-PDRQTVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKE----REREKELEKEQEQEREKERE--KERERQQEKEKELEKEQE
KQRE----MEKERKQEKDRELE-RQKEKEK--ELQKIKE---QE----KECELE---K--
--EREKLEEKIEPREPNLEPT----V----------------------------------
---------------------------------EKPESENSCNKEEEPIFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHIARSARDHAVSLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPDD--IRPEAALDQEQI---TAAYSVE---HNQLEVHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-TSNQSGCFEVPDQKTLSTPHEERISA--IESQ
PSRKRSVSHGSNHTQKPDEQRNE-PSASIPKVTSRCIDSKEP-TERPEEKPKKEGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKMEKKDLLPPAPPPQPPAP--I-QAQSVPPP------
-------IQPEAEKVP----SPET--ATLAQKPSQNTEKSLEPVNS------VQVEPAVK
TVNQQ--TVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPI-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPPYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAMPTNGTV---NNVAQEPVNTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTTGVELVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSPSIPPLASAPLPPSTLASVSAS----T--SVPVPA------
-TLTPVLASTSAPVTASTLAPVLASASAPVQV---SPLAPV---SASASVSASVPASTSA
AA-I---TSSSAPA--SAPAPTPIL--ASVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSVPTPAPAASSA--AAPIITAPTV-----PAS-A----PTASVPLVPASASAP
--APT----------------AVSAPTPAPTAPAQTQAQTHKPVQNPLQT--TPQSSKQP
--PPSVRLPSAQTPNGTDYGATG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLLEKSTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKASPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNSK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSTSGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQPQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPASVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNAKS----SSQIPAQPSV--
AKVPFGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--RERERERQQEKEKELEKEQE
KQRE----MEKERKQE--KELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----I----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIAKVTSRCIDSKEP-TERPEEKPKKEGFM---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KMTEKVVVKPE---KKDLPPPPPPPQPPA--LI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDAEKSLEPVST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPI-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAAVP-------
ATLTPILASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
VAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PAASVPLVPASA---
---------------PAPATTPVSAPTSAPPAPAQTQAQTHKPVQNPLQT--PSQPSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSAATVRGTDPVTTKETKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPFPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASAPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TGQPLIALPQTLQSPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKAKQRAEVL
Q-----------STQRFFSEQQQ--S-KQI-GGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAS--SSLTSDQDEK-PG-QDESTA-GTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSSKASENTENRKEPDEVSNTKS----SSQIPTQPSV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKEREKEWEREKELEKEQEREQEKERE--KERERQQEKEKELEREQE
KQRE----MEKERKQEKEKELE-RQQEKEK--ELQKTKE---QE----KECELE---K--
-RDREKVDEKTEHKEPTSEPM----V----------------------------------
---------------------------------EKPESENSCNKEDDPVFTRQDSNRSEK
ETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSD
PYPHTEPQQATTP-KAAEEPED--VRPEAPLDQEQI---TAAYPVE---HGQLEVHPKPD
FVRESSETDVQKFLSRSVEDIRPRHTD-TNSQSTCFDVPDQKTITTPQEERISA--GESQ
PARKRSVCHGSNHTQKSEELRNE-PSANIPKVTSRGIDSKEP-AERPEEKPKKEGFI---
--RSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGE---KGEKVTEK-VVKPEKTEKKEPLPPPPAPP---AAPV-QPQSVPPQ------
-------PQPEPEKLP----SVETSPSTLVQKPPQDTEKPLESVSS------VEVEPAVK
TVNQQ--AVTAPVV-KEEKQPEKVISKDLV-TERTRPDSRP---------TAKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RAEHVA-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKSKLPKREERPESKKPI-KPQSSFKPENHVRIDN-RPLEKSFVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPD---SGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTV---NNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNL-DDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-NQTSK
LPPRFAKKQATGTQQVQPPASALTSAPGPGST----------SAPV--PATTPAP-V-PA
STPAPLLASPVASVPAPTTVPVLTSTSAPLPA---LASA-----------SVPVPASTPT
--------TAIASS--PAPAPTPIL--ASASSPASVP-----ILTS--ASIPILAS----
--ALAPASAPPPAISA------------AAV-----PAS-APT---------APTSAPAS
AP----------------TPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KPIQTSQSHGTLTAELWENKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PSTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYSS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-MVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMAQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPIRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAPPPEVAP
APKSWASNKQGGQG---DGK-----WTLEFPSLQAAGDQEKKE--KEANDDSYGPGPSLR
PP-NVACWRDGGKSAG--PSSSSDQDEKLVG-QDENTT-ITSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQAPLGSQYRAMMPPY---MFQQYPRMAYP-PLHGPVRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSTKASENTENRKEPDEVSNTKS----SSQTPAQPPV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLVQQHPP-PDRQGIPGRSGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKFGIVE
KQPSPEEIREREREKE----REREKELEKEQEQEREKER----ERERQQEKEKELEKEQE
KQRE----VEKERKQEKEKELE-RQREKEK--ELQKMKE---QE----KECDLK---K--
--ERE-------------------------------------------------------
----------------------------------------------KPVFTRQDSNRSEK
ETTQVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ-------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPSNSESFEHIARSARDHAVSLPEPRMMWGSD
PYPHAEPQQAPTP-KTNEETED--VRPEAALDQEQI---TAAYPVE---HSQLETHPKAD
FVRESSETEVQKFLSRSVEDIRPHT-D-TNNHSACFEVPDQKTLSSTPEEQISA--LESQ
PARKRSVSHGSNLSQKSEEQRNE-PSVSLPKVTSRCIDSKEP-AERPEEKPRKDSFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KATEKV-VKPEKTEKKDLVSPPSPPAAP----V-QPPSVPAS------
-------VQPEPEKFP----STEP--STLAQKPSQDTEKPLEPVSS------VQVEPAVK
TVNQQ--TAPSPAV-KEEKQPEKAISKDAA-IERTRTDSRP---------AVKKEPTL-P
PRPYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-STPLRQREESETRSESSDFEVMPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKRDEWSENKKPL-KPQSSFKPENHVRMDH-RPLEKPYVRED--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPPYRDNQWNPRQTEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAATKTN
E-V-SLPTNGTV---HNAVQEPANTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERREREEKKNADLNA-----QAVVKAGENVLPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSVGPTCVDPINSSSAHHQ---------
EGAPNGTGQKSSKDSAGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNTNEK----GR-SQTSK
LPPRFAKKQATGTQQAQAPVSALVSAPVP------SSTSALVLASP--GTPVPA------
STATVVVTSPAVLVSAPTQAPVLPASSVPGPA---SPSAP-------------VPSSTSA
P-TT---ASSSASA--STPAPTPIL--ASASTPVSVP-----ILAP--ASIPILAS----
--ALAPASAPPPATAVAAP--AASASV------------------SAASVSLASASA---
-------------------SAPTPTPASAPTVPAQTQAQTHKPVQSPLQT--S-QASKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQSHGSLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKS-DKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPAPAPVRSTDSVTAKETKAVSEMSAEIGTMISVSSAEYASDAK
ESVTDYTTPSSSLPNTVATNNAKMEDALVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPLASGV--------SSSGSGPNAASYSS
FSSASVPQIPVASVTPTTPLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPPVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGL---
-----MIATAGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSTPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPSETLTDPPGVCQEK
VEEKPPPASTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPDVPQ-TQPKPAVPAPPEAAP
VAKSWANTKPGGQDG--PPLPINSYFQQEFPSLPAAGDQEKSGKDKDAAE--DGSGANLR
PQ-NATSWRDGANKNK-SPCSPTDQEAKALG-QEDGSA-TPA-ENDGQKAGDK---R-DV
-RLPQVPQPKLNGQQQPPISSQYRAMMPPY---MFNQYPRMAYPPSMQGPTRFPNS--EP
SRGPRGRGP-PSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLN
FSDDDEQGSSQKEKENS-DEQTPSKDSQSPDGQKETEEQTNAKSATQ--------VSTAA
AKGPYSKSSQL-DQERGGPAPPP--K------SILPPIHHPPPPDRQ--MGRQGPFPPK-
PVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCVT
KPSREDPLKEREREREREREREREREREREKEREREREKEREKEKEKEREREREKEKEKE
EREKL----EKAKEQE---------------VEKEKEKEVEKEEKENEK-------EK--
-EEEKPAHEVPEPVEPVATPVV-EKQ----------------------------------
---------------------------------ESETKNNKEEKEDQAVFTRQDSGRNEK
EVSQVTHENEPDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ-------Q
QGVLPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDMPPIHPG--IMPPKPLMRREQLEGSAAGSDSFEHMARSAREHSVPLSEPRMMWGSD
PYPHAESQQSTSPPKVLEEPDDLRSEAH--LEQERVAVPASAYPVE---HNQLDSHPKTE
FFRESGEVEVQKFPSRPLEDVQPLQTD-TPNTAVNFEGVSEKVTRSSPEELVPV--GESH
SSLKRSISHGSSHSLKSEEQRSE-TAANIPKLSNR--ETKET-IERLEIKPKKEILITN-
--RTSEGPKPEKTFKPKSETRWGPRPGYSRRDEGGDRPVRRSGPIKKPVLRDMKEEREQR
EEREQRKEKEGEKTASEKPGKPEKSDKNPPPPPPPPPPPPPPPPP-PPPPPPPP------
-------PPPPPPPPP-PP-PP-P---PPPPPPPP----PPPPPPP--------PPPPPP
PPPPH--AQPPAPPSKEDKQAEKVLSKEVV--EKPRLETRP---------VKRE--PGLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDPKP
RSEHVP-SGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDS
IIKGKHPKREERADGKKPP-KPL-SFKPENNIRVDN-RSLEKTYIRDY-ENKPKPGFLPK
GEPSRRGRG--GMYRRGGRDPGARPPRPSTIRRPAYRDNQWNPRQTEIIKPE---DGEPP
RRNEHYGPIPIDKR-PPKFERKFDPNRERPRRQRPARPPRQDKPPRFRRLKEREAASKIS
EVVASSTTSATV---NNAVSEPSNPALDVSGSKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADAAA-----QVAAKAGENAGAPKREIAKRSFSSQRPGIDRQNRRG-NNG
PAKPGRNFSGPRSERRS-GPPPRSGKRGPFEEQAAPVPGVDPTNGSALHQE---------
DGGVTAAGQKTTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVQ----GKKLLAVLGMLSRVQK
LPSKK---VTLG---------------------FYT-----SQWGAVSTPPPPPP-PPPP
PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP---PPPPPP------PPPPPPPPPPPPP
P--P--PPPPPPPP--PPPPPPPPPP--PPPPPPPPP-----PPPP--PPPP--------
--PPPPPPPPPPPPPPPPP--PPPPPPPPPP-----PPP-PPPPPPPPPPPPPPPPPPPP
PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAQAQAQ------AQAQPPCPAQSPAQP
QAPVAAQSQAAGGTASTDYTVPG-KVLQNTQPHNGLGAELWDNKVPPTAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAPSPEGTKPGQEGGVDLGIETIQFGAPASSGSD
NEVGPVLSEKSTDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKN
RKVKDAQQ-GEPEGQEKPSPTSVRSPEPVTAKETKAASELSTEIGTMISVSAPEFGTNTK
ESVTDYTTPS-SHPNTVATSSTKMEETLVTNVPL-PHTLPLPRRETLQQSSSLTPVSPAT
VDLTLKMESARKAWENSPNMGEKSSPVTSAASPIAGGSS------SSSSNTGPSSGTYSS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTS-SL
ASASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPTFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRS
QQAFMQSGLSQPSPVVLSGTALHNFPAVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQ-----VT
VPLPGSQISLPNFGS-TAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPA
GTQHSMIAATGKISEMDLKAFGGGID-VKPGTPPVSGRSTTPTSSPF-RASSTSPNNQSN
KMNSIVYQK-QFQSAAAAVRMTQ-PFPAQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQQPQNKPIGG-KAPKVEE-NGSKASEAIADSAGVCQDK
AEEKPSPAPAA-------TPKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPA-AQPKPGVTAPPEVAP
APKSWASNKQGGQGD--VGIQVNSQFQQEFPSLQAAGDQEKKD--KESNDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPSSSEQDEKLPG-QDESTA-GTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPGLPSQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKSSENTENRKEADEVCNTKS-----SQITAQPQG--
AKGPYGKGPPF-NQERG---P-SAHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKRGIME
KQPSPEEIRERERERE----REREKELEREQEQELERLEP--KET--------AVEPVVE
KQFASV--MCSL-KYCADTALS-FQ---NQELEMQRVRP---VRKDTKFECSLP---T--
-FGEGTC-----GWELSLAPSS-NNK----------------------------------
---------------------------------IKHPFKNSYYAEEKPVFTRQDSNRSEK
ETTQVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQVQLRYQDVL------LFQE
QGVLPQTVSSQPSGSTVPPPPHRPVYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSANSSESFEHMARSARDHAVSLSEPRVMWGSD
PYPHAEPQQATTP-KAPEEPED--IRPEAAHDQEQI---TAACPVE---HSHLEAPPKAD
FVRESSETEAQKFLSRSVEDVRPHPTD-TNNQSACFEVPDSKALSTPSEDRISG--VESQ
PVRKRSVSHGSNHTQKLEEQRNE-PSACVPKVTSRCPDSKEP-AERPEEKPRKDGFI---
--RSSEGPKPEKVYKSKSETRWGPRPGSNRREEGNDRPVRRSGPIKKPVLRDMKEERELR
KEKEGEKVE---KVPEKV-IKPEKTEKKDLLPPLPPPAPV------QPQSVTPP------
-------TQPEPEKLS----STEV--SAVAQKPSQDIEVPLETVSS------VQVEPAVK
TVTQQ--TIVAPVV-KEEKQTEKPVGKELA-VERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQ-SFKPENHVRIDN-RPLEKPYVRED--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWSPRQAEATKPE---DGEQP
RRHEQFIPMPVDKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-A-ALPTNGTV---NNVVQEPVNTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLIA-----QAVVKAGDNGLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKKGPFDDQSATTAVVDSVNGSSAHHQ---------
EGVLNGTGQKTSKDPTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQVTGTQQVQSTASTSAP----VPS----------------------------
--------SPATTVPASTVVPI--------------------------------------
------------------------------------------------------------
-------PVSPP------------------------------------------------
-------------------------------------APANKPAQNPLQT--VPQSSKQ-
--PPPSRLPSAQTPNGTDYVATG-KSIQTPQSHGTLTAELWDNKVTPPAVLND------L
SKKLGPISPPQPPSVSAWNKPLTSFGSTSSEKGAKNGQDSGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKS-DKIAEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-GEPEGQEKQSSTTIRSPDPSTTKETKAVSEMSTDIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMAQIPVASVTPTTSLSDIGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFSTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVTQAQELFTSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPNALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPFRLLPQVRTASPAK
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNAKS----SSQVPAQPPV--
AKVPFGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKEKERQQEKEKELEKEQE
KQRE----MEKERKQE--KELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----I----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIAKVTSRCIDSKEP-TERPEEKPKKEGFM---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KMTEKVVVKPEKTEKKDLPPPPPPPQPPA--LI-QPQSVPPP------
-------IQPEAEKFP----STET--TTLAQKPSHDAEKSLEPVST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPI-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPPTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPVAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKK-TDLNA-----QTAVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPVASAPLPHSTSASVPAST------SAAVP-------
ATLTPVLASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SALASVSASVPASTSA
VAI----TSSSAPA--SAPAPTPILA--SVSTPTSVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPLAPASA---
---------------PAPATTPVSAPTSAPPAPAQTQAQTHKPVQNPLQT--PSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADRIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATIRSTDPVTTKETKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASAPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIG-GKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVAVSRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGSGWASKQEQHEEEKPPEVPPAAQPKPGVVAPPEAPP
APKSWASNKQSGQG---DGVQVNSHFQQEFPSLQAAGDQEKKE--KDANDEAYGSGSNIR
PS-KFG--RDGG-KSG--ILSPGDQENKLPG-QEDGTA-GTAEQNDALKAGEK---R-LP
GVPPQLPQPRVNGQQQPGLASQYRAMMPPY---MFQQYPRMAYP-PLHGPIRFPPSLSDA
NKGPRGRGPPPSWAPEP-ERPSILSATELKELDKFDNPDVDPDEGWAGAQMEVDYTEQLN
FSDDDEQGGNQKENRDDGE-EQASKGSENSEGQKENEGPSTKP------PQ--TLPQPPV
TKGPYSKGPPF-NQSLLHEKNNSIHLPP---HPKSLMQQHPP-PDRQAGPGRQGPFPPKQ
PVPDEDEAWKQRRRQQTEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKYGIVE
KQPSPEELREREREKEREREKEREKERERE----REKEREREKEREREREKERELERQRE
KERELEKERELERQREKERELE-QQREKERELEKEHEKAQE-QERERQREEELERERE--
-KEQENVEVKLEPKEPVIEAVV-EKQ----------------------------------
---------------------------------ENESSSNKETREEQPSFTRQDSNRSEK
ESTPAVHETEPDSGSLPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPPAAPSQPSAGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDLPPMHPG--MMPPKPLIRRDQMEGSPASSESFEHIARSARDHAVSLNEPRMMWGSE
PYPHAEPQQANTAPKVTEEPED--LRPEAPLEQEVI---TTAYPVE---HNQLDSHPKTE
FFRETGEAEVQKFPSRSLEEVRPHHTE-LTNPAPTAEAADQNIAPGSQEEPVLI--GESQ
AVQKRSVSHGSSHPVKAEEPRNE-TSANIPKVNSRCTDIKEP-AERPEDKPKKEVFT---
--RSCDGPKLDKPYKSKSETRWGPRPSSNRRDEGIDRPIRRSGPIKKPVLRDMKEEREQR
KEKEGEKGE---KPMEK-VVKPEKIEKKEPPPPAPA-------QI-PPQPLPPP------
-------SKPEPEKPA----SDAS---NVAKKPPQDPDKPLEATES------VQAESAVK
PVSQQ--PAPPPAP-KEEKQPERVIGKDHV-FERPRPDSRP---------IKKD--PTLP
PRTYWKDARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGQSRDYPHYRDPKP
RTEHLP-SGALRQREESETRSESSDFEIVPKRRRQRGSETDSDSEVHESASDTLLSDKDS
LSKGKHPKREERPENKRPP-KPLLSFKPENSIRVDG-RPLDKPYGRED-DSKPKPGFLPK
GEPSRRGRGAAGTFRRGGRDPSGRPPRPSAIRRPAYRDAQWSPRQAETPKLE---DGEPP
RRQEPFVPGPADKR-PPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKVN
DAAPASAPSGAV---NNVAQEQAGAAADVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLSA-----QAAAKAGENALPPKREIAKRSFSSQRPGVDRQNRRG-NGG
PPKSGRNFSGPRSERRN-GPSLRSGKRGPFEDQTGGNASVDPVNGSSM-HQ---------
EGGPNGTGQKNSKEAGGKKREEPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVKKCHNSRPV----TE---LGL
DPSSVAQWKEPGLGSQRSCVRIP------ALPLVSYVTVGNLTWDNLITLYLPQR-LEQC
SAHSKCLTNTSIIITLLL-LKCLKIAS---QT---TNLDRL-----QLEVNCGV----SR
YFSSYSTQGKQAPL--CRILPEPLLSQALEPTGNLNF-----TLPSTTWLQTLYSS----
--VLAQGSSNEKGR--------------------------------SQNSKLPPRFAKKQ
QQVAV----VQQAQAPLPAATPA--PAPAAQTVAQPQSQTPTPTPTPTPTPSQPQTAVQ-
--PQGQTANAPNATNGTDYVATG-KPSQNVPSHGTLGAELWDNKVAPTAVLND------I
SKKLGLISPPQPPSVSAWNKPLTSFGPAAPSEGAKNGQESGVELGIETIQFGAPASNGSE
NEAAPVLPEKSPDKLPEPKEQRQKQPRAGPIKAQKLPELSPVENKEHKPGPIGKERSLKN
RKVKDVQQ-VEPEGQEKTSPPAVRNGEPVPAKETKAVAEMSAEIGTMISVSAPEFAANTK
ESVTDYTSPS-SLPSTVATSNTKMEETLVTNVSI-SHSRSFCERVCVRTSISMQVGPGVD
YGTWFAMESARKAWENSPNVREKSSPATSTAAPITSVG--------VSSSSGPNPANYNS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFSTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFNSSLQPYRS
QQAFMQSSLSQPSPVVLSGTALHNFPAVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLS
QASGLGGSQLIDTHLLQARASLTQASNIYSGQVQQPGQSNFYNTAQSPNALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTPPQAPAQSLNRPTQVSQPFRGLIPA
GAQHNMIATTGKMSEMDLKAFGSGID-VKPGTPPIGGRSTTPTSSPF-RASSTSPNSQSS
KMNSIVYQK-QFQSAAATVRMTQ-PFPPQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--T-KPMGG-KAPKVDS-DTAKPSEPLTDPPGVCQEK
VEEKPPPAPTT-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDENYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKQLG-QDESTA-ITSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSEA
NKSLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSTSPKE-SSSE-DQTAKTPESTENRKEVDEASSTKS----SSQIPAQPPV--
TKSPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQ-IPGRQGPFPSKP
PVPDNDEIWKQRRKQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKLGIIE
KQPSPEELREREREKE------RERELEKEKERE--------------------LEKEQE
KQRE----MERARQQ--EKELE-QQREKEQ--ELQRLRE---QE----KEGEPK---E--
----QEKEEKVEPQEPVVEPA----T----------------------------------
---------------------------------ENQESENNCKKEEEPIFTRQDSNRSEK
ETTQVVQEAEPESGAQPRP----GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQ---QQQ
QGVLPQTVPSQPSNGSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLIRRDQMEGSPNSSESFEHIARSARDHGISLSEPRMMWGSD
PYH-AEPQQAATP-KSAEETGD--ARPETAMDHEHM---TAAYPVE---HSQLETHSKTD
VARDSTETEEQKFLSRSLEDVKPRHVD-TNTQSACFDVIDQKSLPTSAEERISA--LESQ
PARKRSVSHGSNHAQNAEEQRNE-PSVSIPKVINRCMDSKET-VEKPEEKPRKDGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKLE---KVTEKV-VKAEKPEKKDLPLPLPPPAPAQP--Q-PQPLVSPP------
-------VQPEPEKPP----STET--STLTQKPSQD-EKPLEPVGS------VQVEPVVK
TVNQQ--SVAAPTV-KEEKPPEKVINKDVG-IERSRPDSRL---------AVKKDSSL-P
TRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTREYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
VSKGKLPKREERPENKKPV-KPQSSFKPENHVRIDN-RPLEKPYIREE--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPATLRRPAYRDNQWNTRQAEPPKPE---DGEPP
RRHEQFMPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-LVPSNGTA---NNVVQEPVNPPADISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADKSS-----QAVVKAGESVLPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKGGKRGPFDDQASGTAGADPVSGNSAHHQ---------
EGVPNGAGQKNSKDAAGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVVQVWSKKNIGEK----GR-SQTSK
LPPRFAKKQATGTQQIQAPP----S----APVPVSS--SAPGLTAP--AAAAPAS-T-P-
-APVPILASATALVPVSTPAPVLTSCPAPVPT---SA-------------SAPVPASTSS
PVTA---S-SSSQP--SVPAPTPVL--ASASTTVSVP-----ILTS--ASIPILAS----
--ALAPATVSSPTPVVSAT--AVPSISTPAV-----PAS-A----PTASVPLAPASAAST
------------------------VPPPASTVQTQTQTQTHKPVQSPLPP--SAPSSKQP
--PPSIRLPSAQTSNGTDFVAAG-KSMPTSQSHGSLTAELWDSKVAAPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKATDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPAVVRSTDPETAKETKAVSEMSAEIGAMISVSSAEYGSDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNLREKGSPVTSTAPPIVSGV--------SSSASGPSTANYSS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSIQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNPQPIPILYDHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPQLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMMATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSVVYQK-QFQSAPATVRMAQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DLKAKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KTQRVDS-DTSN-PETLSDPPGTCPEK
VEEKPPPAPTI-------TTKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
VLKSWASNKQGGQEMKPIGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPP-SDQDEKLPG-QDDNTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALTSQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGPRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSD-DQGSKAAENSENRKEADEVCSTKS-----SQIPAQ-PV--
VKGPYGKGPPF-NQERG---P-SSHLPP---PPKLISQQHPP-PDRQAVPGRPGPFPPKQ
QVPDGDEIWKQRRRQQSEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEVREREREKE----REREKELEKEQEREREKEKE--RERERQQEKEKELEREQE
KQRL----MEKERKQEKEKELE-RQQEKEK--ELQKPRE---QE----KECELK---Q--
--EREKVEEKVEPKEPTSEPV----V----------------------------------
---------------------------------EKQESENNSNKEEEPVFTRQDSNRSEK
ESTQVANETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPTSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PTMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRIMWGSD
PYPHTEPQQGTSP-KATEEPEG--VRPEASLDQEQI---TAACPVE---KSQLEVHPKAD
FLRESSETEVQKFISRSVEDIRPHHTD-TNNQSACFEVPDQKNVSTPQEERISA--GEIQ
PVRKRSVSHGSNHTQKSEEQRNE-PSGSIPKVASRYIDSKEP-ADRSEEKTKKDGYI---
--RSSEGPKPEKLYKSKSETRWGPRPGSNRREESNDRPIRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEKI-VKPEKTEKKDPLPPPPPPPA----PS-QPQSLPPP------
-------PQPELEKVP----STEN--SALTQKPSQDTEKPLEPPNS------IQMEPAVK
TVNQQ--TLLAPVV-KEEKQPEKVVSKDLV-IERPRPDSRP---------AVKKESML-P
PRTYWKEVRDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDPKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKHPKREERSENKKFI-KPQSSFKPENHVRIDN-RPLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGSRPSRPPTLRRPTYRDNQWNPRQTEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-TVPTNGTV---NNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVVKTGENALPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PSKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQIASVTGIDPINGNSAHHQ---------
EGASNGTGQKNSKDIPGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVL
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGSQQPQSPASAPALASAPVPALA----SA--------------------
----PVPASSSAPVPASTSAPVPASTSAPVPA---STSAPV-------------------
-----------------------------------------------------LAS----
--STVPVPTSTPTSAPS--------------------------------STLSPATSS--
------------------SSAPAPVPA-------------------------------PT
--PILASAPSAQTPNGTDYVATG-KSIQNPQSHGALTAELWDNKVASSAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGAKNSQESGVEIGIDTIQFGAPSSNGNE
NEVVPVLSEKPTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPNSATVRSTDPVTTKETKVVSEISTEIGSMISVSSAEFGTNTK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNLREKGSPVTSTAPPIASGV--------SSSGSGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-ESSKPPETLTDPPGVCQEK
VEEKPSPAPTI-------AAKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKQLG-QDESMS-ITSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPTLASPYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSSKTPESTENRKEVDEASGTKS----SSQIPAQPPV--
AKSPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQ-VPGRQGPFPSKP
QVPDNDEIWKQRRKQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKFGIIE
KQPSPEELREREREKE----REREKELEKEREQERERERE--RE----------LEKERE
KQKE----MEKERQQ--QKELE-QQREKEQ--ELQRVRE---EE----KEVELK---E--
----KEKEEKVEPQEPILEPM----A----------------------------------
---------------------------------EKQESESNCNKEEEPIFTRQDSSRSEK
ETTQMVQEAEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ-----QQ
QGVLPQTVPSQPSNGSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLIRRDQMEGSPNSSESFEHIARSARDHGISLSEPRMMWGSD
PYH-AEPQQAATP-KSAEEPRD--ARTEPALDHEQI---TAAYPVE---HSHLETHSKTD
VARDSAETEGHKYLSKSVEDVRPLRAD-TNNQSACFEVIDQKSLPTPPEERISA--LESQ
PARKRSVSHGSNHTQKADEQRSE-PSVSITKVTSRCIDSKET-VEKPEEKPRKDSFL---
--RSSEGPKPEKIYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTERV-VKTEKTEKKDLPPPLPPPAPV----Q-PQPLVPPP------
-------VQPEPEKLP----STET--SASAQKPSQDNEKPLEPVPS------VQVEPAVK
TGNQQ--SIAAPTV-KEEKQPEKVISKDVG-VERLRPDSRP---------PVKKESPL-P
PRTYWKDARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RTEHGP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKFPKREERAENKKPM-KPQ-SFKPENHVRIDN-RPLEKPYIRDE--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGSRPSRPATLRRPAYRDNQWNPRQAEPPKPE---DGEPP
RRHEQFMPIPADRR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTG
E-V-LVTTNGTV---NNVVQEPVNPPGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADVSS-----QTVVKAGENVLPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKSGKRGPFDDQSSGTAGVDPVNGNSAHHQ---------
EGAPNGAGQKNPKDATGKKREDTKPGPKKTKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVVQVWNKKNVNEK----GR-SQASK
LPPRFAKKQATGTQQAQAPA----S----APAPVSS--SAAVLPPP--AASVPAT-A-PA
PAPVPVLASATALVPASAPAQVLTSSPAPVPA---SA-------------STPVPVSTSS
ALTA---S-SSPQV--SVPAPTPIL--ASASATASVP-----ILTS--ASIPILAS----
--ALAPASVSSPTPVVSAP--AGPTISTPTA-----PTP-APVPAPATQ-----------
-----------------------TAPAPAPAPPAQTQTQTHKPVQSPLPP--PTSSSKQP
--PPSIRLPSAQTSNGTDYVATG-KSIQAPQSHGSLTAELWDNKVAAPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQEAGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKPTDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKN
RKVKDAQQ-AEPEGQEKPSPAVVRSTDPGTSKETKAVSEMSAEIGAMISVSSAEYGTDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNIREKGSPVTSTAPPIVSGV--------SSSASGSSTANYNS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSIQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPQLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMMATTGKMSEMELKAFGGGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KGQKVDS-DSSKSPETLTDPPGACQEK
VEEKPPPAPTI-------TTKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVTASPEVAP
VPKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KDANDDNYGPGPSLR
PP-NVACWRDGGKSAG--LSP-SDQDEKLPA-QAENTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPGLASQYRAMMPPY---MFQQYPRMAYPPPVHGPMRFPPSLSET
NXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXE-DQSTKSSENTENRKEADEVNSTKS----SSQTPAQPSI--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQSVPGRGGPFPPKQ
QVPDEDEIWKQRRRQQSEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKLGIVE
KQPTPEEVREREREKE----REREKELEKEQEHEREKEKE--KEKERQQEKEKELEREQE
KQRE----MEKEKKQEKEKELE-QQWEKEKENK---TR-------EQERECELE---S--
-DEREKVDK--VPKEPVLEPVV-EK-----------------------------------
---------------------------------------SVSNSSEEPVITKQDSNRSEK
ETTQAAHETEPESGAQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVSSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSTRDHAISLSEPRVVWGSD
PYSHAEPQQATTP-KITEEPED--VXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXX---
--XXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXX------XXXXXX--------
-------XXXXXXXXX----XXXXX-XXXXXXXXXXXXXXXXXXXXX-XX--XXXXXXXX
XXXXX--XXXXXXX-XXXXXXXXXXXXXXX-XXXXXXXXXX---------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX--X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXRIDN-RPVDKPYVRDD--DKSKLGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-A-TIATTGTV---TSVVQEAVSTAGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVVKAGENVLPPKREIAKRSFSSQRPGVDRQNRRS-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGXXXXXXXXXXXXXXXXXXXXXXX---------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVWNKKNANEK----GR-NQTSK
LPPRFAKKQSTGTQQAQPPASAPATGVATTAP-------------------ASAA-V-PA
SASAAVLASASAPIPVSALAPVPPSTTAPLLA---SPSTSV-------PASAANPASTSA
VATASSSAPVPAAI--PIPAPTPILASV-----------------SAPTSVPILAS----
--ALVPASPPTPASSASAP--AAPTVSAPAA-----PAS-V----PATSVPLAPASTPAP
APV-----------------------PSAPSAPAQTQAQTHKTVQNALQS--TAQTSKQP
--PPLIRLPSAQTPSGADYVTTG-KSIQNSQCHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASAEGTKNGQESGVEIGIDTIQFGAPASNGSE
NEVVPVLLDKPNDRIPEPKEQRQKQPRAGPIKAQKLPDLSPVESKEHKPGPIGKERSLKN
RKVKDVQQ-VEPEGQEKPNPAAGRSTDPVTTKETKTVSEMSAEIGTMISVSSAEFGPNAK
ESVTDYTTPSSSLPNTVATDNAKMEDTLVNNXXX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXX---------------------------X-XX----------------XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXGGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPTFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-MVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARASLTQASNLYSGQVQQPGQTSFYNTAQSPSALQQXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPS--ATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRVTQ-PFPAQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIAS-KPQRVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTM-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKLSG-QEESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQTALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQVSKAPENTENQKEADEACSTKS-----SQVSAQAPV--
TKGPYGKGPSF-NQERG---A-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIREREREKE----QERQKELEKQQEQEREKERE--RERERKQEKEKELEKEQE
KQKE----MEKERKQ--EKELE-RQREKEK--QLQNMKE---QE----KECELE---K--
--EREKVEEKIELKEPTIEPV----V----------------------------------
---------------------------------EKQESENNCNKEEEAVFTRQDSNRSDK
ESTPVTHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGTVPLPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARPTRDHAVSLSEPRMMWGSD
PYPHAEPQQATTP-KATEESEA--VRSEAALDQEQI---AAAYPVE---HSQVEAHPKAD
FVRESSETEVQKFLSRSVEDIRPHHTE-SNNQSACFEVSDQKTLSGPQEERISA--VESQ
PARKRSVSHGSNHIQKSEEPRSE-PSASIPKVSSRCIDSKEP-TERAEEKPKKEGFI---
--RTSEGPKPEKVYKSKSETRWGPRPGSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KVTEKV-VKLEKAEKKDLPSAPPPSAPV------QPQSGPPP------
-------VQPELEKFP----SPET--SALTPKPSQDTEKPLEPVSN------VQAEPAVK
TVNQQ--AAAAPTAPKEEKQPEKVISKDFV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREDRSENKKPI-KLQSSFKPDNHVRIDN-RPLEKPYVRDD--EKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPTYRDNHWNPRQIDPPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTV---TNVVQEPVNTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNTDLNT-----QAVVKTGENVLPPKREVAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSVCTTGVDPVNGSSAHHQ---------
EGAPNGTGQKNSKDATGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-GQTSK
LPPRFAKKQATGTQQAQSSPSAPTL----ASAPVPPSTSVPVPACT--SAPVPAS-----
-ASAPVLASAPAAVPASTSASIPVSTPTPIPA---SAPIPA---S------------T-S
ATAT---TSSSVPA--SVPPPTPIL--ASVSSPASVP-----ILTS--ASIPILAS----
--ALAPASAPAPAPVVSVP--AAPIISAPAT-----PGS-AP----VSSVPLAPASTPAP
VPP--------P------VPAPTPGPTPAPTLPAQTPVQTHKPVQNPLQP--TAQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQNPQSHGTLTAELWDNKVASPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQEGGVEIGIDTIQFGAPSSNVNE
NEVVPVLSEKATDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKASPAIVRNTDTVTTKETKSVSEISTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNIREKGSPVTSAAPPIPSGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTSPQAQAQSLTRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KVQKADS-DSSKPPETLADPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAPPPEIAP
APKSWASNKQ--------GIQVNSQFQQEFPSLQAAGDQ---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDXXXXXXXXXXXX---XXXXXXXXXXXXXRHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKPPEVPP-AQPKSGVTAPPEVPP
VAKSWASNKQGGQGDXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXXXXXX
XXXXVASWREGGKSAG--PSSPSDQEDKLPGQ-DDGAN-GPVEQNDSHKTTEK---R-LP
GVPPQIPQPKLNGQQQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPIRFPPSLSEA
NKGLRGRGPPPTWAPEP-ERPSILSATELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGGSQKDSKDNXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXX--
XXXXXXXXXXX-XXXXX---XXXXXXXXXXXXXXXXXXXH-PPPDRQAGPGRSGPFPPK-
QVPDEDEAWKQRRRQPSELSAAVERARKRREEEERRMEEQRKAACAEKLKQLNEKYGIVE
KQPSPEEIREREREKEREREREKERERERIR----EREREREKEREREREKERELERERE
KERE----LEREREQEKERELE-RQREAEKELEKEREREQERE-------KEQQ------
---RKKREKKXXXXXXXXXXX----X----------------------------------
---------------------------------XXXXXXXXXXXXEQPVFTRQDSNRSEK
ETPQVAHEIEPDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQSAPSQPSGGAVPPPPHRALYQPMQPHPQHLASMGFDPRWLMVQSYMDPRMMSGR
PAMDIPPIHQG--MIPPKPLMRRDQIEGSTANSESFEHIARSARDHAVSLTEPRMMWGSD
PYPQVEPQQASSPPKLAEEPKDLR--PEAPLEQELM---VASYPAE---HSQLDTHPKAE
FFRDISETEVQKFPNKSLEDARPPPTD-TNSQATCFELADENVVPTPQDDQSPI--GEGQ
SVRKRSVSHGSSHSQKPEEARNE-APANIPKTTSRCTDTKEP-SERLEDKPKKEGFV---
--RPSEGPKLEKLYKSKSETRWGPRPGSSRRDEGGDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKVE---KP-TEKVVKPEKPEKKDPPPPLAQVQ---------PQPLPPP------
-------PQTEPEKPP-------TETSSLAKKLSQDTVKPSETVDN------VHIEPAIK
TSNQQI---PPLSVTKEEKQPERVIGKEQG-VERSRIDSRP---------IKKE--PTLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHSRDYPHYRETKP
RAEHVP-SGSLRQREESETRSESSDFEIVPKRRRQRGSETDSDSEVHESASDTLPSDKDS
LSKGKHPKREERPENKKPL-KPLLSFKPENSVRVDNNRPLEKLYVRDD-ENKTKPGFLPK
GEPTRRGRG--GMFRRGGRDPGGRPPRPSTLRKPTYRDNQWNPRQTEAPDDE--------
-----------------------------------------HXXXXFRRLKEREAASKIS
DVA-ATSTNVTI---NNAVQEPVSATGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADLSA-----QAAAKAGDNVLPPKREIAKRSFSSQRPGIDRQNRRG-NSG
PPKSGRNFSGPRNERRN-GPSSKSGKRGPFEDQSIGMTSVDPASGSSVHHQ---------
DGGPNGTGQKSSKDASGKKREEPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTIQSPALALALSA------------
----------------PVLASVPAPAPAPIPALVPP---------GLTSAPAPTPAPAPT
PALVPALTSAPIPIPASTQTSVLASSALV-------------------------------
-----------STPSSSVPALTPDLATASVPDPIPVSALAIPLFNISSNSAPVLAASPL-
----DSAPSSISSLTASAP-----VV-------SLNPSSSSSVPAP---VSFVPIFVSAS
----------LV------------------STPVLTXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSKNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLTEKPPDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDVQQ-AEPEGQEKSNPPSVRNPDAVTTKETKTVTEMSSEMGTMISVSAPEFGANTK
ESVTDYTTPSSSLPNAVATSNSKMEETLVTNVPL-PNTLPLPKRETLQPSSSLSPAPPTT
FNLTFKMESARKAWENSPNVREKGSPATSTAAPIASGS--------SSSASVPSTGNYNS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAXXXXXXXXXXXXXXX---XXXXXXXXXX
XXXXXXXXXXXXXPTSVQQIPIPIYAPLQGQHQAPLSLGAGPAVSQAQELFNSPLQPYRS
QQAFMQSSLSQPSPVVLSGTTLHNFPAVQHQELAKAQSGIAFQQTSNAQPIPILYEHQLG
QASGIGASQLIDTHLLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-XXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXMSEMDLKAFGSGID-VKPGTPPIGGRSTTPTSSPSXXXXXXXXXXQSS
KMNSIVYQK-QFQSAAATVRMTQ-PFPAQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQS---KQIGG-KAQKVDS-DSNKTPETLTDPSGVCQDR
VEDKPPPTPTT-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDSYGPGPSLR
PP-NVACWRDGGKSAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQTALTSQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSGE-DQVSKASENTENRKEADEVCNTKS----SSQISAQAPV--
AKGSYGKGPSF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAIPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIREREREKE----REREKEIEKEQEQERE-ERE--KERERQQEKEKELEKEQE
KQRE----MEKERTQEKEKELE-RQREKEK--ELQKMKE---QE----KACELE---K--
--EREKVEEKIEPKEPALEPV----V----------------------------------
---------------------------------EKQESENNCNKEEEAVFTRQDSNRTEK
ESTPVTHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGTVPLPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSTRDHAVSLSEPRMMWGSD
PYPHAEPPQATTP-KATEESED--VRSEAALDQEQI---TATYPVEHIEHSQLDAHPKTA
FVRESSETEVQKFLSRSVDDIRPHHTE-SNNQSACFEVTDQKTLSVPQEERISA--VESQ
PARKRSVSHGSNHTQKSEEQRHE-PSASIPKVTSRCIDSKEP-AERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEVEKVE---KVTEKV-VKPEKMEKRDLLPPPPPPAPI------QPQSVPSP------
-------VQPEPEKCP----STET--STLSPKPSQDTEKSLEPVSS------VQVEPAVK
TVNQP--TVAAPTV-KEEKQPEKVISKDFA-IERPRPDSRP---------AIKKESTL-P
PRTYWKEGRDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKSKLPKREDRSENKKPI-KPQSSFKPDNHVRIDN-RPLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKPE---DGEPP
RRPEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTV---NNVVQEPINTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----PAAVKAGENILPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSVGTAGVDPVNGSSAHHQ---------
EGAPNGTAQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-GQTSK
LPPRFAKKQATGTQQAQSSASAPTL----ASVPVPPSSSAPVPAST--SAPVPAL-----
-ASAPVL--------ASTSAPVPASTSTPVPL---STLAPV---SASTSAPAS----T-S
ATAT---TSSSAPA--LVPAPTPIL--ASVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAVSVP--AAPIISTPAA-----PAS-A----PTASVPLAPASAP--
----------------------TPTPTPAPILPAQTQTQTHKPVQSPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQSHGNLTPELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGVEIGIDTIQFGAPASNGNE
NDVVPVLSEKSADKVPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPAMVRSTDTVTTKETKSVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKASPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLTRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------STKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYTTLSLFNTYKGKSLETQKTTVAARHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKPPEVPP-AQPKSGVTAPPEVPP
VTKSWASNKQGGQG---DGVQVNSHFQQEFPSLQAAGDQEKKE--KDGTDDAYGPGPSLR
PP-NVASWREGGKSAG--PSSPSDQEDKLPG-QDDGAN-GPVEQNDSHKTTEK---R-LP
GVPPQIPQPKLNGQQQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPIRFPPSLSEA
NKGLRGRGPPPTWAPEP-ERPSILSATELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGGSQKDSKENCE-EEAPKTSESAENRKEDDEGSSNKSQ--------LHPQSMV
SKGPYGKGPPF-NQEKN---S-SAHLAL---PPKSLAQQHPP-PDRQAGPGRSGPFPPK-
QIPDEDEAWKQRRRQPSELSAAVERARKRREEEERRMEEQRKAACAEKLKQLNEKYGIVE
KQPSPEEIREREREKEREREREKERERERIREREREREREREREKEREREKEKELERE--
--------REREREQEKERELE-RQREAEKELEKEREKE---KE----REKELQ---K--
-EKEREKEEKLEREEPSLQPV----V----------------------------------
---------------------------------DKQQSESCNKSEEQPVFTRQDSNRSEK
ETPQVAHEIEPDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQSAPSQTSSGAVPPPPHRTLYQPMQPHPQHLASMGFDPRWLMVQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQIEGSTASSESFEHIARSARDHAVSLTEPRMMWGSD
PYPQVEPQQASSPPKLTEEPKDLRHRPEAPLEQELV---ATSYSVE---QGQLDAHPKAE
FFRDNGETEVQKFPNKSLEDTRPPPTD-TNSQVTCFELADQNVVPTSQDDQTSV--GESQ
SVRKRSVSHGSNHSQKTEEPRNE-APANIPKITNRCIDTKEP-MERLEDKPKKEGFI---
--RPSEGPKLEKLYKSKSETRWGPRPGSSRRDDSGDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKVEK---PMEK-VVKPEKPEKKDPPPPPAA-------QV-QTQPLPPP------
-------SQPEPEKPP----SETS---SSTKKLPQDTVKPSETVDS------VHIEPAIK
TSNQQ--TAPLHV-SKEEKQSERVISKEQG-IERPRIDSRP---------IKKE--PTLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHSRDYPHYRETKP
RAEHVP-SGSLRQREESETRSESSDFEIVPKRRRQRGSETDSDSEVHESASDTLPSDKDS
LSKGKHPKREERPENKKPL-KPLLAFKPENNVRVDNNRPGEKLYVRDD-ENKTKPGFLPK
GEPTRRGRG--GMFRRGGRDPGGRPPRPSTLRRPTYRDNQWNPRQAEAPKPD---DGEPP
RRHEQFIPISADKR-PPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKIS
DGAATCVTNGTI---NNVVQEPVSAAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADLNA-----QAAAKTGENVLPPKREIAKRSFSSQRPGIDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPSSKSGKRGPFEDQSIGTAGVDPANSSSVHHQ---------
DGGPNGAGQKNSKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTIQAWNKKSSNEK----GR-NQNSK
LPPRFAKKQQQATVVQQPQTATPP------P-----------------------------
---------------------VQGLTQ---------------------------------
------------------------------------------------AQVPVQV-----
----QPTTTQT-------------------------------------------------
------------------------------------------PNQ------------SPP
--SAQPQVQATNATNGTDYVATG-KSVQHAQSHGPLGAELWENKVAPAAVLSD------I
SKKLGPISPPQPPSVSAWNKPLTSFGSTTSPEGTKNGQESGVEIGIETIQFGAPASNGSE
NEIVPVLTEKPPDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDVQQ-TEPEGQEKSNPPSVRNPEAVTTKETKTVTEMNSEIGTMISVSAPEFGANTK
ESVTDYTTPSSSLPSTVATSNTKMEETLVTNVPL-PNTLPLPKRETLQQSSSLSPAPPTT
FNLTFKMESARKAWENSPNVREKGSPATSTAAPIASGG--------SNSVSVPSTGNYNS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPAS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFNSPLQPYRS
QQAFMQSSLSQPSPVVLSGTTLHNFPAVQHQELAKAQSGIAFQQTSNAQPIPILYEHQLG
QASGLGGSQLIDTHLLQARASLTQASNLYSGQVQQPGQSSFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTPPQAQGQGLSRPTQVNQPFRGLIPA
GTQHSMIAATGKMSEMDLKAFGSGID-VKPGTPPIGGRSTTPTSSPF-RASSTSPNSQSS
KMNSIVYQK-QFQSAAATVRMTQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFSAPVQRP
PMALASQMPPPMTTGLMSHP-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSNKTPETLTDPPGVCQDR
VEDKPPPTPTT-------AAKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKQLG-QDESMS-ITSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPTLASPYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSSKTPESTENRKEVDEASGTKS----SSQIPAQPPV--
AKSPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQ-VPGRQGPFPSKP
QVPDNDEIWKQRRKQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKFGIIE
KQPSPEELREREREKE----REREKELEKEREQERERERE--RE----------LEKERE
KQKE----MEKERQQ--QKELE-QQREKEQ--ELQRVRE---EE----KEVELK---E--
----KEKEEKVEPQEPILEPM----A----------------------------------
---------------------------------EKQESESNCNKEEEPIFTRQDSSRSEK
ETTQMVQEAEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ-----QQ
QGVLPQTVPSQPSNGSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLIRRDQMEGSPNSSESFEHIARSARDHGISLSEPRMMWGSD
PYH-AEPQQAATP-KSAEEPRD--ARTEPALDHEQI---TAAYPVE---HSHLETHSKTD
VARDSAETEGHKYLSKSVEDVRPLRAD-TNNQSACFEVIDQKSLPTPPEERISA--LESQ
PARKRSVSHGSNHTQKADEQRSE-PSVSITKVTSRCIDSKET-VEKPEEKPRKDSFL---
--RSSEGPKPEKIYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTERV-VKTEKTEKKDLPPPLPPPAPV----Q-PQPLVPPP------
-------VQPEPEKLP----STET--SASAQKPSQDNEKPLEPVPS------VQVEPAVK
TGNQQ--SIAAPTV-KEEKQPEKVISKDVG-VERLRPDSRP---------PVKKESPL-P
PRTYWKDARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RTEHGP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKFPKREERAENKKPM-KPQ-SFKPENHVRIDN-RPLEKPYIRDE--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGSRPSRPATLRRPAYRDNQWNPRQAEPPKPE---DGEPP
RRHEQFMPIPADRR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTG
E-V-LVTTNGTV---NNVVQEPVNPPGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADVSS-----QTVVKAGENVLPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKSGKRGPFDDQSSGTAGVDPVNGNSAHHQ---------
EGAPNGAGQKNPKDATGKKREDTKPGPKKTKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVVQVWNKKNVNEK----GR-SQASK
LPPRFAKKQATGTQQAQAPA----S----APAPVSS--SAAVLPPP--AASVPAT-A-PA
PAPVPVLASATALVPASAPAQVLTSSPAPVPA---SA-------------STPVPVSTSS
ALTA---S-SSPQV--SVPAPTPIL--ASASATASVP-----ILTS--ASIPILAS----
--ALAPASVSSPTPVVSAP--AGPTISTPTA-----PTP-APVPAPAASVPLAPAS----
------------------TTTTAPAPAPAPAPPAQTQTQTHKPVQSPLPP--PTSSSKQP
--PPSIRLPSAQTSNGTDYVATG-KSIQAPQSHGSLTAELWDNKVAAPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQEAGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKPTDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKN
RKVKDAQQ-AEPEGQEKPSPAVVRSTDPGTSKETKAVSEMSAEIGAMISVSSAEYGTDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNIREKGSPVTSTAPPIVSGV--------SSSASGSSTANYNS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSIQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPQLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMMATTGKMSEMELKAFGGGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KGQKVDS-DSSKSPETLTDPPGACQEK
VEEKPPPAPTI-------TTKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDENYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKQLG-QDESTA-ITSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSEA
NKSLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSTSPKE-NSSE-DQTAKTPESTENRKEVDEASSTKS----SSQIPAQPPV--
TKSPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQ-IPGRQGPFPSKP
PVPDNDEIWKQRRKQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKLGIIE
KQPSPEELREREREKE----RERERELEKEKERERE------------------LEKEQE
KQRE----MERARQQ--EKELE-QQREKEQ--ELQRLRE---QE----KEGEPK---E--
----QEKEEKVEPQEPVVEPT----T----------------------------------
---------------------------------ENQESENNCKKEEEPVFTRQDSNRSEK
ETTQVVQEAEPESGAQPRP----GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ----QQQ
QGVLPQTVPSQPSNGSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLIRRDQMEGSPNSSESFEHIARSARDHGISLSEPRMMWGSD
PYH-AEPQQAATP-KSAEETGD--ARPETAMDHEHM---TAAYPVE---HSQLETHSKTD
VARDSTETEGQKFLSRSLEDVKPRHVD-TNTQSACFDVIDQKSLPTPTEERISALALESQ
PARKRSVSHGSNHAQNAEEQRNE-PSVSIPKVTNRCMDSKET-VEKPEEKPRKDGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKLE---KVTEKV-VKAEKPEKKDLPLPLPPPAPAQPQPQ-PQPLVSPP------
-------VQPEPEKPP----STET--STLTQKPSQD-EKPLEPVCS------VQVEPIAK
TVNQQ--SVAAPTV-KEEKPPEKVINKDVG-IERPRPDSRL---------AVKKESSL-P
TRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTREYPQYRDNKP
RTDHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
VSKGKLPKREERPENKKPV-KPQSSFKPENHVRIDN-RPLEKPYIKDE--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPATLRRPAYRDNQWNTRQTEPPKPE---DAEPP
RRHEQFMPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-LVPSNGPA---NNVVQEPANPPADISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNAEMSS-----QAVVKAGESVLPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKGGKRGPFDEQASGTAGADPVSGNSAHHQ---------
EGVPNGAGQKSSKDAAGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWSKKNIGEK----GR-SQTSK
LPPRFAKKQATGTQQIQAPP----S----APVPVSS--SAPVLTAP--ATAVPAS-T-P-
-APVPILASATALVPVSTPAPVLTSCPAPVPT---SA-------------SAPVPASTSS
PVTA---S-SSSQP--SVPAPTPIL--ASSSTTVSVP-----ILTS--ASIPILAS----
--ALAPATVSSPTPVVSAT--TVPSISTPAV-----PAS-A----PTASVPLAPASAA--
--------------------------STAPPPASAVQTQTHKPVQSPLPP--SAPSSKQP
--PPSIRLPSAQTSNGTDFVAAG-KSIPTSQSHGSLTAELWDNKVAAPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNE
DEVVPVLSEKPTDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPAVVRSTDPGTAKETKAVSEMSAEIGAMISVSSAEYGSDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNLREKGSPVTSTAPPIVSGV--------SSSASGPSTANYSS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSIQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPQLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMMATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMAQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DLKAKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KAQRVDS-DTSK-PETLSDPPGTCPEK
VEEKPPPAPTI-------TTKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSAKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVTAPPEVAP
APKSWASTKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDSYGPGPSLR
PP-NVACWRDGGKSAG--SPSPSDQDEKLPS-QVDSTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALAAQYRAMMPPY---MFQQYPRMAYPPPVHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-EQGSKSSENTENRKEADEVNNTKS----SSQIPAQPSV--
AKGLYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPERQAGPGRAGPFPPKQ
QVPDEDEIWKQRRRQQSEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKLGIVE
KQPSPEEIREREREKER-------------------------EQRERQQEKEKELEREQE
KQRE----MEKERKQEKEKELE-QQREKEK--ELQKTRE---QE----KERELE---Q--
-KEREKAEEKVEPKEPALEPV----I----------------------------------
---------------------------------EKQASENSSTKEEEPVFTRQDSSRSEK
ETTQVAHETEPESGAQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQQQQQQ
QGVLPQSVSSQPSGGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARPARDHAISLSEPRMMWGSD
PYPHVEPQQATTP-KITEEPED--GRPEAPMDQEQI---AAAYPVE---HSQLESHPKAD
FLRETCETEVQKFLSRSVEDIRPHHSD-TNSLPACFEVSDQKTVSTPQEERISA--GESQ
PVRKRSVSHGSNHTQKSEEQRNE-PSASIPKVTSRCIDSKEP-AERPEEKPKKDGFV---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREDGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKVT------EK-VVKPEKTEKKDALPSPPPPSAP----T-QPQSAPPP------
-------PPPEVEKPP----SIET--STVAQKPSQDTEKPLEPLNS------VQVEPTVK
PVNQQ--TASAPTV-KEEKPPEKVITKDIV-IERPRPDSRP---------ALKKESTLQT
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHPRDYPQYRDAKP
RTEHMP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKREERSENKKPV-KPQFSFKPENHVRIDN-RPLEKPYMRDD--DRPKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKPE---DGELP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-TVATNGTV---NNVVQEAVSTAGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKTGENVLPPKREIAKRSFSSQRPGVDRQNRRGSNNG
PPRSGRNFSGPRSERRS-GPPSKSGRRGPFDDQSAGTAGVDPINGGSTHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQTAGTQQAQSPASGPAMASAPAPALASAAVPASAS------APVPA------
--------PTSVPMP------VSALTPVPPPA---SASPSV-----SLPASAPAPACTSA
---T---ATASSSA--PVPAPTPILASVSAPAPASVP-----ILASTVASVPILAS----
--ALGAASTPAAAPTASSP--AASTASAPAA-----PAS-A----PAAPVPLAPASASAP
AP-----------------------SAPGPSAPAQTQVQTHKTIQNSLQP--TTQTSKQP
--PPLIRLPSAQTPNGADYVTTG-KPIQNSQCHGTLTAELWDNKVAPAAVLSD------I
SKKLGPISPPQPSSVSAWNKPLTSFGSAASAEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSDKPNDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVESKEHKPGPIGKERSLKN
RKVKDGQQ-VEPEGQEKPSPATGRSTDPVTTKETKTVSEMSAEIGTMISVSSAEFGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PSALSLPKRETMQQSSSLSSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSAAPPLASGV--------SSSASGAGTASYSS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTG-SL
PSAGHFSQLSCMPSLIAQQQQSPQVYVSQSAA--VTQIPTFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPSFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIAATGKMSDMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIAS-KTQRVDS-DPSKPAETLTDPPGVCQEK
VEEKPPPAPTM-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQA-----------ETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNTKS----SSQIPAQPSV--
AKVPYGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQ-EKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENSCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAVSLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLSAPQEERISA--VESQ
PSRKRSVSHGSNHTQKPDEQRSE-PSAGIPKVTSRCIDSKEP-IERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKPLEPVST------VQVEPAVK
TVNQQ--TMAAPVV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHIP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPHSSFKPDNHVRIDN-RLLEKPYVRDD--DKAKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNMAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASE-----
---------------------SIVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFQ---------AQSSASVPPLASAPLPPSTSASVPAST------SAPLP-------
ATLTPVPASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
AAI----TSSSAPP--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALASTSAPTPAPAASSP--AAPVITAPAI-----PAS-A----PTASVPLAPASASA-
---------------PAPAPTPVSAPNPALPAPAQTQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTASLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIGGGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILRVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNTKS----SSQIPAQPPV--
AKGPYGKGPPF-NQERG---T-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKE----REREKEIEKEQEQEQEKERE--KERERQQEKEKELEKEQE
KQRE----MEKERKQEKDRELE-WQKEKEK--ELQKIKE---QE----KECELE---K--
--EREKLEEKIEPREPNLEPT----V----------------------------------
---------------------------------EKQESENSCNKEEEPIFTRQDSSRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--TRPEVALDQEQI---TAAYSVE---HNQLEVHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-TSNQSGCFEVPDQKTLSTPQEERISA--VESQ
PSRKRSVSHGSNHTQKPDEQRNE-PSASIPKVTSRCIDSKEP-TERPEEKPKKEGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKTEKKDLLPPAPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKVT----SPET--ATLAQKPSQDTEKSLEPVSS------VQVEPIVK
TVNQQ--TVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKTI-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPPYRDNQWNPRQSEIPKPE---DGEPP
RRHEQFIPIVADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVTTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSACTTGVDLVNGSSTHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-NQTSK
LPPRFAKKQATGIQQAQSSPSIPPL----ASAPLPPSTLASVSAST--SALVPA------
-ALTPVPASTSAPVTASTLCPVLASTSAPVQA---SPLAPV---SASASVSASVPASTSA
AA-I---TSSSAPA--SAPAPTPIL--ASVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPTLAASSP--AAAIITAPTV-----PAS-----APTASVPLVPASASAP
AP----------------ASTPVSAPTPAPTAPAQSQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEIVPVLLEKSTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKASPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNSK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSSSGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQPQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPASVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAS--SSLTSDQDEK-PG-QDESTA-GASEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKASENTENRKEPDEVSSTKS----SSQIPTQPSV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKEREKEREREKELEKEQEREREKERE--KERERQQEKEKELEREQE
KQRE----MEKERKQEKEKELE-RQQEKEK--ELQKTKE---QE----KECELE---K--
-RERDKVDEKIEHKEPTSEPM----V----------------------------------
---------------------------------EKPESEDSCNKEDDPVFTRQDSNRSEK
ETTQAAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSD
PYPHTEPQQATTP-KATEEPED--VRPEAPLDQEQI---TAAYPVE---HGQLEAHPKPD
FVRESSETDVQKFLSRSVEDIRPRHTD-TNSQSTCFDVPDQKTIATPQEERISA--GESQ
PARKRSVCHGSNHTQKSEELRNE-PSASIPKVTSRGIDSKEP-AERPEEKTKKEGFI---
--RSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGEKGEKVTEK-VVKPEKTEKKEALPPPPVPP---AAPV-QPQSVPPQ------
-------PQPEPEKLP----SVETSPSTLVQKPPQDTEKPLESVSS------VEVEPAVK
TVNQQ--TVTAPTV-KEEKQPEKVISKDLV-TERTRPDSRP---------AAKKESTV-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RAEHVA-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DRDS
LSKSKLPKREERPESRKPG-KPQSSFKPENHVRIDG-RPLEKPFIRDD--DKPKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPD---SGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTV---NNVVQEPVNATGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTSGADPVNGSSAHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-NQTSK
LPPRFAKKQATGTQQVQPPASALTSAPGPGST----------SAPV--PATIPAP-V-PA
S---------------PATVPVLTSTSAPLPA---LASA-----------SAPVPASTPA
--------TATASS--PAPAPTPIL--ASASSPASVP-----ILTS--ASIPILAS----
--ALAPASAPPPAISA------------PTV-----PT--------------------AP
AP----------------TPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KPIQTSQSHGTLTAELWENKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-MVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPIRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPSSSDQDEKLLG-QDEGTA-VTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQCRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKTSESTENRKEADEVCNTKS----SSQTSAQPPV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQAVPGRPSPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPAPEEIREREREKE----REREKELEKEQEQERVKERD--KEKERQQEKEKELEKELE
KQRE----MEKERKQEKEKELE-RQREKEK--ELQKLKE---QE----RECESK---K--
--EREKVEEKSEPTEPILEPV----A----------------------------------
---------------------------------EKQESENCCHKEEEPVFTRQDSNRSEK
ETTQVLHEAEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLAQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PTMEIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLPEPRVMWGSD
PYPHAEHQQAATP-KAAEESEG--IRPENALEQEQI---TTAYPVE---HSQLETHPEAD
FVRESSETDVQKFLSRSVEDIRPHHAD-KNNQSACFEGPDPKTLSAPPEERISA--LESQ
PSRKRSVSHGSNHAQKSEEQRNE-PSGSIPKVTSRCIDSKDL-AERPEEKPRKDGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KVMEKV-VKPEKTEKKDLLPPPPPSPAP----I-QTQSVPPP------
-------VQPEPEKLP----STET--SAVTHKPSQDTEKPVETVSS------VQVEPAVK
IVNQQ--TVAAPTV-KEEKQPEKVISKDVG-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPEQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPPRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQSSFKSENHVRIDN-RPLEKPYVRDD--DKLKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-PLPTNGTI---NNLAQEPASTAGDIPGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVVKTGENTLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGIAGVDSVSGGSAHHQ---------
EGAPNGTGQKNSKDSAGKKREDAKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANDK----GR-SQTSK
LPPRFAKKQATGTQ---------QT----ASAPTST--SAPVLIPP--TVPVPA------
STATLVLASPTALVPVSTPAPVLTSAAAPVLT---SV-------------SAPVPASTST
AVTA---AASSTST--SAPTSAPIL--ASVSAPASVP-----ILAS--ASIPILAS----
--ALAPASVPAPAPAVTAP--TVPAVSTPTA-----SVS-S----PAAPVPLVPASA---
---------------------ATPSPAPAPTAPAQTQAQTHKPVQNPLQT--STQPSKQP
--PPSIRLPSAQAPNGPDYIATG-KSIQTPQSHGTLTAELWDNKVSSPAVLND------I
SKKLGPISPPQPPAVSAWNKPLTSFGSATSSEGTKNGQESGVEMGIDTIQFGAPASNGNE
NEVVPVLSEKSTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTVKEPKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYSS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMSSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KTQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATFSLYNTYKGKSLETQKTTVAARHGLQSLGKVAVSRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQDQSEDEKTPEVPP-PPPKP-VVPPPEVPA
VAKSWASTKPGVQG---EGVQVNRYFQQEFPSLQAAGEQEKT-KDKDATDDNYGPGPSLR
PQTDVASWREGGGRNLGTPS---EQESATTVPEDGTTNASLTAIQDQGKIGEKRDNRLLP
CA-ATQPQLKLNG-QQPGVPPAFRGMMPPFAGNMFPSYSKLPFP-QMQGPTRYPTPAEAS
RAPRGERRPAHSWAAEGIERPSIISANELKEL---DNLDTEADEGWAGAQSEVDYTEQLN
FSDDDEQSSSHKKRDDRISKTEQSHGKESSDAHKEPDDGSATTV-------SQTAPAASG
PKGPFGKGPSLDTQLSLEK-----SIPPL-LQPKTAPQQQP-SQSRTGAAGRQATLPPR-
--PSEDELWKQRRRQQAEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKFAAST
STGSSEKTQLDKAPEEISVP--EKSTFEPSLEEEKITE--------DEPIKETSPEGEDT
------------SVQEGNYEEEIAQPEAEPPQESGSVNAL--DERETDQEGEIFHNERCD
SKQRFHIQWKFNKLKWTL------CS----------------------------------
---------------------------------EYIDVYAYCLTVEQQLFTRKGSVSSER
ESTPPTHENESETGAQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQ-------Q
QGVLSQPTQSQASTSPVPPPQHRPLYQPIQPHPQHLASMGFDPRWLMMQPYMDPRMMSGR
PTMDMPPMHPG--MIPPKPLMRRDQIEGPSAASEPYEHMARSVRDHGVTLSEPRMMWGSE
PYSHSDTQQVTVPSKPSDEPDDYR--SETSVEQEVR---SEPYSIE---HTSFESQHKSD
FFSRPREPDLHSAPAQHSEPSAILQSQEQDTLVSSFEQT---EKPLASEDKVPQ--SEIQ
PVLTRSLSSESTRTLKQEERRVDPLPSKSIIR-----PSEHIKDDRVEEKQRKEGFQNFQ
GPKPLELSKTDKPYKPKSETRWGPRPGSRSREDGSDRPVRRSGPIKKPVLRDMKEERELR
KEKEEEKSG------HEKVSKPDKVERKQPPAVPANSANTAVNKT----------E----
----HDKQSSEPATFPNVGN---TS--ILS----TEQTKSLESVSEPVPKPVVHPAPV--
--N---------QPSKEEK-IVRVVSKDNP-SDKPKVDSKPQGSHPPFSTVPHRREPILP
PRAYRKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGQGRDYPHYRDTKP
RSEQVP-SGSLRRREESETRSESSDFEVMPKRRRQRGSETDSDSEGRESASDTPLSDKES
GNRSKT-RREERPEVKRAP-KSVTALKSDTVGTRADARMTERPFSRDE-DSRTKPGFLPK
GEPSRRGRGA-GGFRRGGRESGMRSTRPPPPRRTGYRDNQWIPRQQEPKQPIAPRLDESE
GRHQESVLPSGEKRTPVKFERKFDSVRDRPRRQRPARPPRQDKPPRFRRLKEREREDVGK
SIEATGASNQ-G---VSASSTTHDLPSDFSGNKTPDLSNHNSSDQANEEWETASESSDFN
ERRERDERKAATSTNTQSPAPTKAIDGLTQSPPKRESAKRSFSSQRPGMERQNRRG-NPG
APKPGRHYSGPRGERRN-ATSLQRGKKGPIDDQAPVMVTADPSSVSSNGHHYHQYHPYAE
DVGSAPAQQKGVKETAGKKKEEPKPAAKKPKEKVDALSQFDLNNYASVVIIDDHPEVTTL
EDSQSNLN-DGFTEVVSKKQQKRLQDEERRKKEEQTVQVCVKMHNAQSHFVHASYVVTIH
L-----KKELSPLSYTPSSASL-------EP--VLNSKDREVL-----SDSVPNK-SFPL
KAVKTCQPTTTLAIRPGLCHSVIPSSSKYGVKSHPRSGKRV---SKNSNVACLDRCDT--
--------GES---------TDGSWSSEVKVLVVLDL-----VLGSSNPSNTFLGD-AAS
-FGIPPDSCKSHSGAVCKPVPEPPVCFVIVLFQIWNKKG-SSEKGRGQNSKLPPRFAKKQ
QQQA--------------------------AAALQAQSTVLASQPSGVQPIPTALTQSQP
QPPVQSQPPTNTPANGTEFTGSVKAPPPPTQQPSALGTELWENKISAPNVLSD------L
SKKLGPINPPQPPSSSAWNKPLTGFVAAGTQEASKNGQESTVDLAMETIQFGAPASSSSD
NEGTSSLSEKAADSLPEPKEQRQKQPRAGPIKTQKIPELGVVLSKEYKPGPIGKERSLKN
RKVKEVQQQVEPETQEKPL-ATVRTTEPVPSKENKTVTEVPADISNMLSVSAPEFGTTAK
TFKPHFTSFSLLLLSINKTRDTKFLTICFLIVPL-PHTLPISRRETLQQSSSLTPVSPAT
VDLTLKMESARKAWENSPNVAEKGSPITSAAPPITST-----------SAVGPTNVPYNS
FSSASMPPIPVASVTPTTSLS--GTGTYTTSSLSTKTTTTSDPPNICKVKPQQLQSSSNM
ASASHFSQLSCLPSLMAQ-QQSPQVYVSQSAAGPAAQIPAFYMDTSHLFNTQHARLAPPT
LTQQQGFQPGLSQVMNIFKIPIPIYAPLQSQHQAQLGLAPGPAVSQAQELFTPSLQPYRS
QQAFLQNNLSQPSPVVLSGAALHNFPGVQHQDLAKAQSSLAYQQTTSTQPIPILYEHQLS
Q-SGLGGSQLIDTHILQTRQGLGQPSNIYSGQVQQPSQTNFYSTAQSPTALQQ-----MT
VPLQGSQLSLPNFGSSPGQPLIALSQALAP-----TPQAQHQSLSRTGQVSQAYRGLIPA
GGQHGMIAAPGKMSDMDLKPYSTSLDHVKPGTPPVAGRSTTPTSSPF-RASSTSPNSQSS
KINSLVYQKHQFTSSAASVRMGQPPFPTQFPPQILSQPNIVPPLVRAPHPNTFQPQVQRP
PMGLPNQMPPQMPTGLMNHP-----------RLHHVSRAPPAPPSGVRVTPAHAAMKAEQ
DLKAKQRAEVLQSTHRFFEQQQHQQS-KPVGP-KPPKTMP-GPTKPSDTMTDPSVCTQEK
VEENPAPAATLAAAAVATSTKPIRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNTKS----SSQIPAQPSV--
AKVPYGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPGEPNLEPM----I----------------------------------
---------------------------------EKQESENSCNKEEEPVFTRQDSSRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFDAPDQKTLSAPLEERISA--VESQ
PSRKRSVSHGSNHTQKPDEQRSE-PSAGIPKVTSRCIDSKEP-TERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKIVVKPEKTEKKDLPPPQPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKCP----STET--ATLAQKPSQDTEKSLEPVST------VQVEPAVK
TVNQQ--TMAAPVV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESIL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHIP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPH-SFKPDNHVRIDN-RLLEKPYVRDD--DKAKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTPASVPAST------SAPLP-------
ATLTPVPASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
AAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTV-----PAS-A----PTASVPLAPASASA-
---------------PAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPPSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGVKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLLEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIGGGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPP-AQPKPGVTAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSVG--SPLTSDQDEK-PG-QDESAA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSTSPKE-NSSE-DQDSKGSENTENRKEADEVYNTKS----SSQIPAQPPV--
AKGPYGKGPPF-NQDRG---P-SSHLPP---PPKLLAQQHPP-PDRQAAPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKEREKEREREKELEKEQEREREKERE--KERERQQEKEKELEREQE
KQRE----MEKERKQEKEKEIE-RQQEKEK--ELQVMKE---QE----KECELE---K--
-KEREKMEEKTEHREPTLEPM----V----------------------------------
---------------------------------EKPESENNCNKEDDPVFSRQDSNRSEK
ETTQAAHEAEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ-----QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQVEGTPNNSESFEHIARTTRDHAISLSEPRVMWGSD
TYPHTEPQQATTP-KATEEPED--VRPEAPLDQEQI---TAAYPVE---HSQLEAHPKAD
FIRESSETEVQKFLSRSVEDIRPHHTD-TNNQSACFDVSDRKTISTPQEERISS--GETQ
PARKRSVSHGSNHTQKSEEQRNE-PSASIPKVTGRCLDSKEP-AERPEEKPKKEGFI---
--RSSEGPKPEKPYKSKSETRWGPRPGSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEKI-AKPEKTEKKEPLPPPPPPVAP----V-QPQLVPPP------
-------PQPESEKFP----SVET--STLVQKPPQDTEKALEPVSN------VEVEPAAK
TVNQQ--TVSAPTV-KEEKQPEK-ISKDLV-TERTRPDSRP---------AIKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RTEHVP-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQ-SFKPENHVRIDN-RPLEKPFVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEVPKPD---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-AVPTNGTV---NNVVQEPVNTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QVVVKAGENVLPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTTGADPVNGSSAHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNASEK----GR-SQTSK
LPPRFAKKQATGTQQAQPPASALVSA----PGPGST--SAPVPATT--SAPVLA------
SAPAPVLASSSAPVSAPAAVPILTSTSAALPT---LASA-----------SAPVPAPAS-
--TS---ATATASS--SVPAPTPIL--ASVSTSASVP-----ILTS--ASIPILAS----
--ALAPASVPSPA--VSAP--TVPTSTP-AA-----PA----------SASTTPASLPAP
TPTPAPAPAAAPTPASTLVQVPALPPAPASTAPGQTQGQIHKTVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQSSQSHGTLKTELWDNKVAPQAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNSQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKMSEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEISTEIGTMISVSSTEYGTNV-
------------------------------KVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSNLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTAQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--N-KQIGS-KAQKVDS-DTSKPSETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNAKS----SSQIPAQPSV--
AKVPFGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQE--KEKE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRES--------------------------------TPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIPKVTSRCIDSKEP-TERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KVTEKVVIKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKSLEPVST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AIKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPM-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKIGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLPSAPLPPSTSASVPAST------SAAVP-------
ATLTPVLASTSAPVPASTLVPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
VAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPLAPASA---
---------------PAPATTPVSAPTSAPPAPAQTQTQTHKPVQNPLQT--PSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKEAKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKAKQRAEVL
Q-----------STQRFFSEQQQ--S-KQI-GGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQGDXXXXXXXXXXXXXXXXXXXX---XXXXX--XXXXXXXXXXXXXXX
XX-XVACWRDGGKSAG--TPVTSDQDEK-PG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAVMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKSLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKASENTENRKEADEVCNTKS----SSQIPAQPSV--
AKGPYGKGPSF-NQDRG----PSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPTPEEIREREREKERER----EKELEKEQEREREKE--REKERERQREKEKELEQEQE
KQRE----MEKERKQEKEKELE-RQQEKEN--DLQKMQE-------QEKECELE---K--
-KEREKVEEKIEHKEPTLEPV----A----------------------------------
---------------------------------EKSDGDNSCSKEDDPVFTRQDSNRSEK
ETTQAAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ-----QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG---IPPHPLMRRDQIEGSPNNSESFEHIARSARDHAISLSEPRVMWGSD
PYPHTEPQQATTP-KATEEPED--GRPEAPLDQEQI---TAAYPVE---HSQLEAHPKAD
FVRESSETEVHKFLSRSVEDIRPHHTD-THNQPACFDVPDLKSVSTPQEERSLA--GESQ
PARKRSVSHGSNHTQKSEEQRNE-PSASIPKGASRSIDSREP-AERPEEKPKKEGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREDGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEK-IVKPEKTEKKEPLPPPPPPAAPAQP---QSVPPPPP------
-------PPPEPEKLP----SVETSTSALAQKPPQDTEKPLEPTSS------VEVEPAAK
TVNQQ--TVTTPAV-KEEKQPEKVISKDLV-TERPRPDSRP---------AVKKESTL-P
PRTYWKDPRDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPPYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKKEERSENKKPI-KPQSSFKPN-HVRIXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX---XXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-X---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX-----XXXXXXGENVLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTAGADPVNGTSAHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKPGPEXXXXXXXXXXXXXXXXXXXVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQAQSPASALAPAPCPGVASASAP--------ATTSAPLPA------
-APAPVLASPSAPLPAAA-VPVLTSSSASLPA---LA---------SASASAPVPASTSA
TT-----------------------------------------------TALLLSA----
--PIAPTA------P----------TSAPTA-----P-----APAP--------------
-----TAPASLPAPAPTSTSALVQVPVPAPTTPAQSQGQTHKPVQSPLQA--TPASSKQP
--PPSIRLPSAQTPNGTDYVAPG-KPLQASQSHGPLTNELWDNKVATPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGAKNSQESGVDIGIDTIQFGAPDSNGNG
NEIVPVLEK-LRDKTYEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATARSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVK
ESVTHYTTPSSSLPNSVATNNAKMEDTLVNNVPL-PNTLPLPKRETIPQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAPAQSLSRPAQVSQPFRGLIPA
GAQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPSEQATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKADS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTM-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNTKS----SSQIPAQPSV--
AKVPYGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERE-EKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENSCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQH------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAVSLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLSAPQEERISA--VESQ
PSRKRSVSHGSNHTQKPDEQRSE-PSAGIPKVTSRCIDSKEP-IERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKPLEPVST------VQVEPAVK
TVNQQ--TMAAPVV-KEEKQPEKVISKDLV-IERPRPDSRL---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHIP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPHSSFKPDNHVRIDN-RLLEKPYVRDD--DKAKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNMAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSAGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAPLP-------
ATLTPVPASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
AAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALASTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPLAPASASA-
---------------PAPAPTPVSAPNPALPAPAQTQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTASLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIGGGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTXXXXXGYQSLGKVGISRRMPPP
ANLTSLKAEKKANDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DXXXXXSQFQQEFPSLQAAGDQEKKE--KEGNDDNYGPGPSLR
PP-XXXXXXXXXXXXX--XXXXXXXXXXXXX-XXXXXX-XXXXXXXXXXXXXX---X-XX
XXX-X---XXXXX-XXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXX
XXGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-TSSE-DQSLKTSENTENRKETDEVSNAKP----SSQIPAQPSV--
TKSPHGKGPPL-NQERG---T-SSHLPP---PPKLLAQQHPP-PDRQALPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIREREREKE----REREKELEKEQEQERKKE--REKERERQQEKEKELEKEQE
KQRE----MEKEKRQEKEKELE-RQGEKEKES--AQLKE---QE----KECALQ---I--
-VSQ--DEKTRNPKEPTLEPV----V----------------------------------
---------------------------------EKQESENNSSKEEEPVFTRQDSNRSEK
ETTQVAHETEPESGCQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQG-QSQS
QGVLPHSVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDMSPIHPX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXX-XXXXXXXXX-XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX-XXX---X-XXXXXX---
--XXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXEVVPEKIEKKDHPPPPPPPVP-----I-QPQSVPPP------
-------TQSDPEKCP----STET--SALAQKPSQDTEKPLEPVST------VQVEPAVK
TVHQQ--TVTAPTV-KEEKQPEKVITKDLV-IERPRPDSRP---------AVRKESAL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHPREYPQYRDSKP
RADHIPPPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSEKKKPI-KPQSSFKPENHVRIDH-RSLEKPYVRDD--DKSKPSFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAETPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPTRERPRRQRPTRPPRQDKPPRFRRLREREAASKPN
E--VAVPANGTV---NSVSQEPVNNAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADSNP-----QAVVKAGENVLPPKREIAKRSFSSQRPGVDRQNRRGGNSG
PPKSGRNFPGPRNERRS-GPPSKTGKRGPFDDQSAGTTGVDPISSSTAHHQ---------
EGAPNGAGQKNSKDSAGKKREDPKPGPKKPKEKVDALSQFDLNNYASV-IIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVVQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATVTQQTPSLASAPTTASAPVPASTSPL-------------------T-PA
STSAPVLASPIAPISASASGPVLTSASAPVST---S--------------TAPVPTSTSA
I-----VTASSAPA--STPAPTPILA--AASTPASVP-----MLAT--PSIPILAS----
--ALAPASSPTPASP--------PSISTPAA-----PAS-----AQTASVPLT-------
-------------------PATVPTPAPVPAVPSQAQALTHKPVQNPLQT--AAQSSKQP
--PPSIRLPSAQAPNGTDYVAAG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAAAAEXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLPDLSPVENKEHKPGPIGKERSLKN
RKAKDAQQ-VEPEGQEKPSPATGRSTDPVTTKETKAVTEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETVPQSSSLTSVPPTT
FSLTFKMESARKAWENSPNLREKGSPVTSTAPPIAGGG--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA--XXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-XXXXXXXXXXXXXXXXX-
-XXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVT
VPLPASQLPLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAPSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPSGLLPQVRTASPAK
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQ-TQPKPAAPAPPEAPP
VTKSWANTKPGGQDG--PALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEETHGSGPSLR
PQN-ATNWREGGNKGN--S----TADQEGLGQEDGNA--TPAEQNDGQKAAEKRDPR---
--LPQVPQPKLNGQQQPPISSQYRAMMPPY---MFNQYPRMAYPPSMQGPTRFPNS--EP
SRGPRGRGP-PSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLN
FSDDDEQGSSQKEK---SDEQTPTKDSQSPDGQKEAEEQTNAKSAT--------QVSTTA
AKGPYGKTQ-PDQDRGG-PVHPKSILPP-----------HPPPPDRQ-IPGRQGPFPPK-
PVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMT
KPSREDPLKEREKEKEEKEKQ---------------------------------------
------------------------------------------------------------
-----PANEAPEPVEPVATPVV-EKQESESRNNKEEKARPVWPAHQNVKGKAGHRRMQEK
KIRGSAIHVAKKQCELFQLFCSLSKPREVDAKSVFKLVELECNREDQPVFTRQDSGRNEK
ENAQVTHESEPDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQYALKSTCYSQH------AQ
KGVLPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDMPPIHPG--IMPPKPLMRRDQIEGSAASSDSFEHIARSAREHAVPLSEPRMMWGSD
PYPHAEPQQASSPPKVLEETDNLR--SEAHLEQERVAVPSAAYPVE---HNQLDSHPKTD
FFRESGEVEVQKFPSRPLEDVQPLQTD-TSNTAANFEGVDENVSRSSPEELAPV--GESH
SSLKRSISHGSSHSLKSEEQRNE-TAANIPKLINRSVESKDI-IERIEVKPKKEVLISN-
--RTTEGPKPEKTFKPKSETRWGPRPGYGRREEGSDRPVRRSGPIKKPVLRDMKEEREQR
EEREQRKEKEGEKIANEKLSKSEKSDKKEAPQMPVPQAEPETSASSGAPPSTPPVS----
------QQLPAPQ--------------------------PV--ASPQLPPAIPQQPPAQP
AAQQQPQAQQPATAVKEEKQTEKAVSKEIV--EKPRLETRP---------VKRE--PGLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKP
RSDHVP-SGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDS
LIKGKHPKREERTDGKKPM-KPL-SFKPENNIRVDN-RSLEKNYIRDD-ENKPKPGFLPK
GEPSRRGRG--GMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKTE---DGEPP
RRNEHYGPIPVDKR-PPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKIN
EAVTSSSTSATV---SNAGNEPSNAALEVSGSKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADVAA-----QVAAKAGENTGAPKREIAKRSFSSQRPGIDRQNRRG-NNG
PAKPGRNFSGPRSERRS-GPPPRSGKRGPFEDQTATVPGVDPTTNNSLHQE---------
EGGVTVAGQKSTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEK----GR-GQNSK
LPPRFAKKQQQQAAAAAAQQAQAQA-----------------------------------
------------------------------------------------------------
----------QA------------------------------------------------
-QAQSPCAAQTPG-----------------------------------------------
------------------------------------------------Q----PQASVQP
Q-----NQAAGGTAASTEYTVSG-KVLQNTQAHNGLGTELWENKVPASAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQEGGVELGIETIQFGAPASSGSD
NEVGPVLSEKSTDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKN
RKVKDAQQ-GEPEGQEKPSPTSVRSPEPVTAKETKATSELSTEIGTMISVSAPEFGTNTK
ESVTDYTTPS-SHPNTVATSSTKMEETLVTNVPL-PHTLPLPRRETLQQSSSLTPVSPAT
VDLTLKMESARKAWENSPNMGEKSSPVTSAASPIAGA--------------GPNSGTYSS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTS-SL
ASASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRS
QQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLS
QASGLGGSQLIDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TAQPLIALPQSLQPPLQHTPPQAPAQNLSRPAQVTQPFRGLIPA
GTQHSMIAATGKISEMDLKAFGGGID-VKPGTPPVTGRSTTPTSSPF-RPVLQVRTTSPI
K-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKPEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEATDDNYGPGPSLR
PP-NVACWRDGGKSAG--PPLTSDQDEKLPG-QDESTA-GSSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALTSQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSEA
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKASENSETRKEADEVCNTKS----SSQIPAQPPV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPAKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKLGIVD
KQPSPEEIREREREKE----REREKELEKEQEREREKERE--KERERLQEKEKEE-REPE
EQRE----LEKERKAEKEKDLE-RQPEKEKELELQRTKE---QEKEGESKK---------
--EMEKVGEKIQHKEPALELL----V----------------------------------
---------------------------------RKTRSESSPNKQGDPVFTRQDSSRGEK
ETTQVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPPTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
AAVDIPPIHHG--MIPPIPLMTRDHIEGSPNSSESFEHITRSARDHAVPLSKPRLMWGSD
PYPHPEPQAATPQ-A--AEEES--VRPEAPLAQEQV---TAAYPVE---HSRPEPRPKAD
FAREPSETEVQKFLSRSVEDIRPHPTD-SSSQPACFDILDQKTATAPHEERPAA--GESQ
PARKRSVSHGSNHPQKSEEQRSE-PPASIPKVTSRCIEPKEP-ADRSEDKPKKDGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGSDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KATEK-VVKAEKTEKKDPVPAPPAPQHPGSA---QAQPAPPA------
-------ARPAAVEPP----STET--AAVAQKPLQDPEKPPEPAGGA-AGG-AEAEPAAR
TAPPQ--AATAPAV-KEEAPPEKAASNDLR-GERPRPDPXX---------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXX
XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX-XXXXXXXXXXX--XXXXXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X-X---XXXXX
XXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
X-XXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXAIQIDHMCE-----QAIVY--QIIVSQLQDMVKHRCH--SPRRNYHQNRSGNGG
PPITGR--SGPRSDRRS-RPPTKGGKRGPFDDQSAGTAGVDPPSGSSAHHQ---------
EGAPNGTGQKNNKDSAGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQAQSPSAALATAPGPASAAVLT------------------------
--------SPSTPLPTSASVPV--------------------------------PAS---
---T---SATTPSS--SVPAPTPILA--SASTPASVP-----ILTS--ASIPILAS----
--ALAPTSAPAPAN--SSP--TAPANSASTA-----PAS---------SAPIP-------
------TPASLPTQAPLPAPSPALVSVPGPTASAQTQGQTHKPVPSPLQT--SAQPPKQP
--PPSIRLPSAQTPNGTDYVATG-KAIQTSQSHGTLATELWDNKVAPPTVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPTVVRSADPVTAKETKAASEMSAEIGTMISVSSAEYGANVK
ESVTDYTTPSSSLPNTVATNNAKMEDSLVNNVPL-PNTLPLPKRETLQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVASAAPPVASGV--------SSGASGPGTASYSS
FSSASVPQIPVASVPPTTSLS--SAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTG-SL
PSASHFSQLSCVPSLMAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFGSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHSFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSTLQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAPSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-MKPGTPPISGRSTTPTSSPSAQATSTSPSSQSS
KMNSIVYQK-QFPSAPAAVRMAQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDTPGVCQEK
AEEKPPPAPAI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPLTSDQDEKLPG-QDESTA-GTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NNSE-DQGSKASENTENRKEADEVCSTKS----SSQIPAQPSVGP
PKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKE----REREKELEKEHEREREKERE--KERERQQEKEKELEREQE
KQRE----MEKERKQEKEKELE-QQQEKEK--ELHKIKE---QE----KECELE---K--
-KEREKAEEKIEHQEPTLEPM----V----------------------------------
---------------------------------EKPENENNCNKEDDPVFTRQDSNRSEK
ETTQVLHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MITPKPLMRRDQMEGSPNNSESFEHIARTARDHAVSLSEPRMMWGSD
PYPHTEPQQATTP-KATEESED--VRPEAPLDQEQI---PAAYPVE---HSQLEAHPKAD
FVRESSETEVQKFLSRSVEDIRPHHTD-TNNQSACFDVTEQKTVSAPQEERISP--GESQ
PARKRSVSHGSNHTQKSEEQRNE-PSASIPKVISRCIDSKEP-AERPEEKPKKDSFL---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEK-IVKPEKTEKKDPLPPPPPPAAP----V-QPQPVPPP------
-------PQPELEKCP----STET--STLVQKPPQDTEKPLEPVSS------VEVEPAAK
TVSQQ--TVTAPPV-KEEKQPEKVISKDLV-IERPRPDSRP---------VVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RAEHVP-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPM-KPQSSFKPENHVRIDN-RPLEKSYIRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPARPSTLRRPAYRDNQWNPRQTEAPKPD---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-AVPTNGTV---NNVVQESGNTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNT-----QAVVKAGENVLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSTGTTGIDPINGNSAHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQTQSAAPGSALASAPGPAST----SAPVPAST--SAPVPA------
STPAAILASPSAPASASAAAPVLTSTSAPLPT---SSSAPV---PAS----------TSA
T-------ATASSP--SAPAPTPILA--SASTPASVP-----ILTS--ASIPILAS----
--ALAPTSAPA--PVVSAP--TAPAISVPAV-----PTS-APNVP---------------
------------APAPALVPVPVSLPAQVPTAPAQSQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNSADYVATG-KSIQTSQSHGTLTTELWDNKVAPTAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVDIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNVK
ESVTDYTTPSSSLPNTVAASNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLPSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAPGLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSMMASFQG-LLP-----
-----------------QVRTAS-PAK---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQNTTSRDGK--EYTLSVFNTHEGKSLGTXXXXXAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTLEVPP-VQPQPGVTAPPEVAP
APNSWANNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEGNDDNYGPGPSLR
PP-NVACWRDGGKSAS--SPSTSDQDEKLPG-QDESTT-GSSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPSLASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXX-XXX--XXXXXXXXXXXXXXXXXXX-----XX--XXXXX--
XXXXXXXXXXX-XXXXX---XXXXXXXXXXXXXXXXXXXHPPPPDRQAVPGRSGPFPPKQ
QIPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKKLNEKLGIVD
KQPTPEEIREKEREKERE----REKELEKEQERVREKE--REKERERQQEKEKELEREQE
KQRE----LEKERKQEKEKELE-RQQEKEKELLK--VK-------EQEKECELE--EE--
-TEREKLEDKLEHREPNLEPM----A----------------------------------
---------------------------------EKKENENTCNKEDDLIFTRQDNDCSEK
ESTQVVHETEIESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVIPQTVSSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDISPIHPG--MIPPKPLMRRDQMEGSANSSESFEHIARSTREHTISVSEPRLMWGSD
PYPHNEPQQASTP-KAAEESED--VRPEAALGQEQI---TATYPIE---HGQTETHPKAD
FVRESSETEV-KFLSRSVEDVRPHHSD-TNSQSTCFNIPDQKAVSTSQEERLSA--GESQ
PARKRSVSHGSSHTQKPEEQRSE-PLASIPKVTNRCADSKEP-VERPEEKPKKDNFL---
--RSSEGPKPEKLYKSKSETRWGPRPGSNRREEGSDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKIE---KTTEK-VVKNEKAEKKEPLPPPPPPTALAQSP-----SVPTP------
--------PQELEKFP----S--TEAASLPQKPPQDTEKALEPVNT------AEVEVTAK
TVNQQ-TVVAA--PVKEEKQPEKIITKDLV-TEKPRSDSRP---------TVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRENKP
RTEHLP-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKKEERTENKKPMNKPQYSFKPDNHVRIDN-RPPEKAFARDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPTRPPTLRRPPYRDNQWNPRQTEVPKMD---DGEPP
RRHEQFIPIPADKR-TPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTG
E--VAVPTNGPL---SSIVPEPVSTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVAKTGENVVTTKREIAKRSFSSQRPGVDRQNRRG-NNG
PQKSGRNFSGPRNERRS-GPPSKSGKRGXXXXXXXXXXXXXXXXXXXXXXX---------
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-NQTSK
LPPRFAKKQATGQQSTASSVPTSTVT----------------------------------
------------------------------------------------------------
--------ASSXXX--SVPAPTPIA---SASSPIPVP-----ILPS--ASIPILAS----
--ALAPASSPTPPSTTSAP--TVSNPDTPTS-----TPT-APISA---------------
--------------TPASVSVPAPVTAPAPTAPAQTQGQTHKPVQNPLQTTTQ--S-SKQ
QPPPSIRLPSAQTSNSTDYVGAG-KPLQTSQSHGTLTAEIWDNKVPPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSSPTPEGPKNGQESGVEIGIDTIQFGAPASSGNE
NEIVPLLSEKT-DKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-AEPEGQEKPNPAPVRSTDPVTTKETKVVPEMSPEIGTMISVSSSEYGTNAK
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSTSGPSTASYNS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAPLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNPAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPGQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSSTSTSSPSGLLPQVRTASPAK
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPLTSDQDEKPSG-QDESTA-GTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPLRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKASENTENRKEADEACNTKS----SSQIPAQPSV--
SKGPYGKGPSF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKE----REREKELEKEQEREREKERE--KERERQQEKEKELEREQE
KQRE----MEKERKQEKEKELE-RQQEKEK--ELQKIKE---QE----KECELE---K--
-KEREKVEEKIEHKEPTLEPV----V----------------------------------
---------------------------------EKPESENTCSKEDDPVFIRQDSNRSEK
ETTQVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ-QQQQ
QGVLPQAVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRREQMEGSPNSSESFEHIARSARDHAVSLSEPRVMWGSD
PYPHTEPQQATAP-KATEEPED--ARPEASLDPEPI---TAAYPVE---HSQLEAHPKAD
FVRESNETEVQKFLSRSVEDIRPRHTD-TNNQSACFDVPDQKPVSTPPEERISAG-AESQ
PARKRSVSHGSNHTQKSEEQRSE-PSVSIPKVPSRCTDPKEP-TERTEEKPKKDGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGSDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVPEKL-VKPEKTEKKDPVPPVPPPAAP----T-QPQSALPS------
-------PQPEPEKFP----STET--STLVQKPPQDAEKPSEPVSS------VEVEPVAK
TVNPQ--IVTAPTV-KEEKQPEKVGSKDL--VERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPM-KPQSSFKPENHIRIDN-RPLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPAGRPSRPSTIRRPAYRDNQWNPRQVEAPKPD---DEEPP
RRHEQFLPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGPV---NNVVQEPVNPAGEISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVVKTGENALPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTTIVDPVNGSSAHHQ---------
EGAPNGTGQKNSKDSTGKKREDPKSGPKKPKEKADALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGPQQAQSPATAPAPASAPGPGPG------------------PGP-A-P-
---------------APAPAPGLTAASSPLPA---AA-------------STPVPPSTSA
AA--------TVSS--AAPASVPVLTSAPASAPASVP-----ILAS--ASIPILAS----
--ALAPASTSTPAAS--AP--AGPT------------------------------PIPTP
TPTPAPAPTLV--PAPPSAPALVPISAPAPTAPAQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTSQSHGTLTTELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKNTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSAATVRNTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVK
ESVTDYTTPSSSLPNTVATNSAKMEDTLVNDVPL-PNTLPLPKRETIQQSSSLTSAPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSPANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLGLGAGPAVSQTQELFTSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQPPGQTSFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSG
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLADPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKVPEVSP-AQPKLGVAAPPEVAP
APKSWASNKQ--------GIQVNSQFQQEFPSLQAAGDQ---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAASPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP----------------------------------------------------------
---------------------------------MFQQYPRMAYP-PLHGPMRFPPSLSET
NXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXX-XXXE-DQVSKASENSESGEEADEVSSTKS----SSQIPAQPSV--
VKGPYGKGPPF-NQXXX---XXXXXXX-----XXXXXXXXHPPPERQAVSGRPGPFPSKQ
QVPDEDEIWKQRRRQQSEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKFGIVE
KQPSPEEIREREREKE----REREKELEKEQEREREKERE--KEKERQQEKEKELEREQE
KQRL----MEKERKQEKEKELE-QQQEKEEEL----------------------------
------------------------------------------------------------
--------------------------------------------PEEPVFTRQDNNRSEK
ESTQGSPETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PTMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHALSLSEPRIMWGSD
PYPHTEPQQATTP-KAAEEPED--VRSEAPLDQEQI---TATYPVE---NSQLEVHPKAD
FLRESSETEVQKFLSRSVEDSRPHHTE-TNNQSTCFEILDQKTXXXXXXXXXXX--XXXX
XXXERCISHGSNHTQKEE-QRNE-PLASIPKVTSRYIDSKEP-TERSEEKMKKDGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREESNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVSEK-IVKPEKMEKKDSLPPPPPPPAP----S-QPQSVLPP------
-------PQPELEKVP----SIEN--STSAQKPSQDTEKPLEPLKS------IQVEPAVK
TVNQQ--TVSAPAV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDTKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQ-SFKPDNHVRIDN-RPLEKPYVRDD--DKFKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKPE---DGEPP
RRHEQFIPVPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-TVPTNGTV---NNVVQEPINTTGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAAVKTGENVLPPKREIAKRSFSSQRPGVDRQNRRS-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQCAGTTGVDPTNGSSAHHQ---------
EGVPNGTGQKNSKDVTGRKREDPKPGPKKPKEKVDALSQFDLNNYAXXXXXXXXXXXXXX
XXXXXXXXXXXX------------------------XXXXXXX-----------------
-----XX--XX-------------X----X---XXX--XX--------------------
--------XXXX--X---------------------------------------------
XXXS---APATVAT--PTPAPTPILASAS----ASAP-----ILASAPVSIPILAS----
--ALAPASTPTPAPAVSAP--TVLAVPSPST-----PAS-AP----TTPVP---------
-------------------------LAPAPTAPAHSQAQTHKPVQSPLQS--TTQTSKQP
--PPSIRLPSAQTPSGTNFVATG-KSIQNSQSHGTLTAELWDNKVTSPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
ESVTDYTTPSSSLPNTVATSNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFK------------------------APPLASGV--------SNSGGGPSPANYSS
FSSASVPQIPVASVTPTTSLT--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTN-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFSTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQSQHQPQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQSSNTQPIPILYEHQLG
QASGLGSSQLIDTHLLQXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXVT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHATPQAQAQSLSRSAQVSQPFRGLIPA
GTQHSMIATTGKMS-MELKAFGSGID-IKPGT-PISGRSTTPTSSPSEQASSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPASTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDENYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKQLG-QDESTA-ITSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSEA
NKSLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSTSPKE-NSSE-DQTAKTPESTENRKEVDEASSTKS----SSQIPAQPPV--
TKSPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPPPPDRQ-IPGRQGPFPSKP
PVPDNDEIWKQRRKQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKQLDEKLGIIE
KQPSPEELREREREKE----RERERELEKEKERE--------------------LEKEQE
KQRE----MERAKQQ--EKELE-QQREKEQ--ELQRLRE---QE----KEGEPK---E--
----QEKEEKVEPQEPVVEPA----T----------------------------------
---------------------------------ENQESE-NCKKEEEPVFTRQDSNRSEK
ETTQVVQEAEPESGAQPRP----GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ----QQQ
QGVLPQTVPSQPSNGSVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLIRRDQMEGSPNSSESFEHIARSAREHGISLSEPRMMWGSD
PYH-AEPQQAATP-KSAEETGD--ARPETAMDHEHM---TAAYPVE---HSQLETHSKTD
VARDSTETEGQKFLSRSLEDVKPRHVD-TNTQSACFDVIDQKSLPTSTEERISA--LESQ
PARKRSVSHGSNHAQNAEEQRNE-PSVSIPKVTNRCMDSKET-VEKPEEKPRKDGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKLE---KVTEKV-VKAEKPEKKDLPLPLPPPAPAQP--Q-PQPLVSPP------
-------VQPEPEKPP----STET--STLTQKPSQD-EKPLEPVGS------VQVEPVVK
TVNQQ--SVAAPTV-KEEKPPEKVINKDVV-IERSRPDSRL---------AVKKDSSL-P
TRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTREYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
VSKGKLPKREERPENKKPV-KPQSSFKPENHVRIDN-RPLEKPYIREE--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPATLRRPAYRDNQWNTRQAEPPKPE---DGEPP
RRHEQFMPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-LVPSNGTA---NNVVQEPVNPPADISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADMSS-----QAVVKAGESVLPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKGGKRGPFDDQASGTAGADPVSGNSAHHQ---------
EGVPNGAGQKNSKDAAGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVVQVWSKKNIGEK----GR-SQTSK
LPPRFAKKQATGTQQIQAPP----S----APVPVSS--SAPVLTAP--ATAVPAS-T-P-
-APVPILASATALVPVSTPAPVLTSCPAPVPT---SA-------------SAPVPASTSS
PVTA---S-SSSQP--SVPAPTPIL--ASASTTVSVP-----ILTS--ASIPILAS----
--ALAPATVSSPAPVVSAT--AVPSISTPAV-----PAS-A----PTASVPLAPASAAST
------------------------VPPPASTVQTQ--TQTHKPVQSPLPP--SAPSSKQP
--PPSIRLPSAQTSNGTDFVAAG-KSMPTSQSHGSLTAELWDSKVAAPAVLND------I
SKTLGPISPPQPPSVSAWNKPLTSFGSATSSEGTRNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKATDKVPEPKEQRQKQPRAGPIKAQKLPDLSLVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPAVVRSTDPGTAKETKAVSEMSAEIGAMISVSSAEYGSDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNLREKGSPVTSTAPPIVSGV--------SSSASGPSTANYSS
FSSASMPQIPVASVTPTASLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSIQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNPQPIPILYDHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPQLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMMATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSVVYQK-QFQSAPATVRMAQ-PFPAQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DLKVSTVLMASR--ARVCL-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNTKS----SSQIPAQPSV--
AKVPYGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKDRERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENSCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FIRESSEAQVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLSAPQEERISA--VESQ
PSRKRSVSHGSNHTQKPDEQRSE-PSAGIPKVTSRCIDSKEP-IERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKPLEPVST------VQVEPAVK
TVNQQ--TMAAPVV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHIP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPHSSFKPDNHVRIDN-RLLEKPYVRDD--DKAKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAPLP-------
ATLTPVPASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
AAI----TSSSAPA--SAPAPTPILA--SVSTPASVT-----ILAS--ASIPILAS----
--ALASTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPLAPASASA-
---------------PAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTASLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQNPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIGGGKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKETDEVSNAKS----SSQIPAQPSV--
AKVPFGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKERENERR----RGKREGE--------------TAGKGERAGEGAG
KQRE----MEKERKQE--KELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----I----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIAKVTSRCIDSKEP-TERPEEKPKKEGFM---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KMTEKVVVKPE---KKDLPPPPPPPQPPA--LI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDAEKSLEPMST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPT-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQ-------------------TSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAAVP-------
ATLTPILASTSAPVPASTLAPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
VAI----TSSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PAASVPLVPASA---
---------------PAPVTTPVSAPTSAPPAPAQTQAQTHKPVQNPLQT--PSQPSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSAATVRGTDPVTTKETKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPFPKRETIQQSSSLTSVPPTT
FSLTFKMESARKEWENSPNVREKGSPVTSTAPPIATGV--------SSSASAPSTANYNS
FSSASMPQIPVASVTPTTSLSG-AAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSTSHFSQLSCMPSLIAQQQQSLQVYVSQSAA---ANV------FSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TGQPLIALPQTLQSPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQVGRCN----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLXXXXXXXXXXXX
XXXXXXXAENKGNDPNVNIVPKDGTGWASKQEQHEEE-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAPPPEIAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDTYGPGPSLR
PP-NVACWRDGGKSAG--PSSSSDQDEKLLV-QDENTA-VTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPTLASQYRAMMPPY---MFQQYPRMAYP-PLHGPVRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSTKASENIENRKEADEVSNTKS----SSQTPAQPPA--
AKGPYGKGPPF-NQERG---S-SSHLPP---PPKLLVQQHPP-PDRQGMSGRSGPFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIREREREKE----REREKELEKEQEQEREKER----ERERQQEKEKELEKEQE
KQRE----MEKERK-EKEKELE-QQREKEK--ELQKMKD---QE----KECELK---K--
--ERE-------------------------------------------------------
---------------------------------------------KEPVFTRQDSNRSEK
ETTQVMHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSGSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHIARSARDHAVSLPESRMMWGSD
PYPHAEPQQATTP-KTNEDSDD--VRPEAALDQEQI---TAAYSVE---HSQLETHPKAD
FVRESSDTEGQKFVSRSVEDIRPHP-D-TNNQSACFEVSDQKTLSSTPEEQISA--LESQ
AAPKRSISHGSNLSHKPEEQRSE-PSISLPKVTSRCIDSKEP-AERPEEKPKKDSFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREDGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KPTEKL-VKPEKTEKKDVVSPPSPPVAP----V-QPPSVPTP------
-------VQPEPEKFP----STET--SALAQKPSQDTEKPLEPVSS------VQVEPAVK
TVNQQ--TAASPAV-KEEKQPEKAISKDIG-IERTRPDSRP---------TIKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEIVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKRDDRSENKKPL-KPQSSFKPENHVRMDN-RPLEKPYIRDD--DKPKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTDAPKLE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAATKTN
E-V-SVPTNGTV---SNMVQEPANTAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADVNA-----QAAVKAGENVSPPKREIAKRSFSSQRPGVDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGPASVDPVNGSSAHHQ---------
EGASNGTGPKNSKDSTGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQA---------------------
----------TGTQPAQAPVSALAS----APVLSST--SAPVLVSP--APPVTA------
STAAVVVTSPAVLVSAPAQAPMLPSASIPVPA---CT-------------TAPVSSSSPA
-PAT---SSSSASA--STPAPTPIL--ASVSAPASVP-----ILAP--ASIPILAS----
--ALVPASAPPPATAVSAP--NVPAISPPAT-----SAS-G----SVASVPLASASVSAP
APVPAPTPTPAP------APAPAPTPASTPTAPAQTQAQTHKPVQNPLQT--S-QSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQPHGSLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKSTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPASSAVRSTDSVTAKETKAVSEMSAEIGTMISVSSADYATDAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKREAIPQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIPSGV--------SSSASGPGTANYSS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTPPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFPSTPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPTSTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAS--SSLTSDQDEK-PG-QDESTA-GTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKASENTENRKEPDEVSSTKS----SSQIPTQPSV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKEREKEREREKELEKEQEREREKERE--KERERQQEKEKELEREQE
KQRE----MEKERKQEKEKELE-RQQEKEK--ELQKTKE---QE----KECELE---K--
-RERDKVDEKIEHKEPTSEPM----V----------------------------------
---------------------------------EKPESENSCNKEDDPVFTRQDSNRGEK
ETTQAAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSNAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSD
PYPHTEPQQATTP-KATEEPED--VRPEAPLDQEQI---TAAYPVE---HGQLEAHPKPD
FVRESSETDVQKFLSRSVEDIRPRHTD-TNSQSTCFDVPDQKTIATPQEERISA--GESQ
PARKRSVCHGSNHTQKSEELRNE-PSASIPKVTSRGIDSKEP-AERPEEKTKKEGFI---
--RSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGEKGEKVTEK-VVKPEKTEKKEALPPPPAPP---AAPV-QPQSVPPQ------
-------PQPEPEKLP----SVETSPSTLVQKPPQDTEKPLESVSS------VEIEPAVK
TVNQQ--TITAPTV-KEEKQPEKVISKDLV-TERTRPDSRP---------AAKKESTV-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKP
RAEHVA-PGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DRDS
LSKSKLPKREERPESRKPG-KPQSSFKPENHVRIDG-RPLEKPFVRDD--DKPKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPD---SGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-AVPTNGTV---NNVVQEPVNATGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTSGADPVNGSSAHHQ---------
EGAPNGAGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-NQTSK
LPPRFAKKQATGTQQVQPPASAPTSAPGPGST----------SAPV--PATIPAP-V-PA
STPAPLLASPAASVPAPATVPVLTSTSAPLPA---LASA-----------SAPVPASTPA
--------TAAASS--PAPAPTPIL--ASASSPASVP-----ILTS--ASIPILAS----
--ALVPASAPPPAISA------------PTV-----PAS-APT---------AP----AP
AP----------------TPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KPIQTSQSHGTLTAELWENKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFSTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-MVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVNYGMVT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPIRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKPSQTAKAKDGKTKYATLSLFNTYKGKSLETQKTTVTARHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKPPEVPQ-VQPKPVAPAPPEVAP
VAKSWASTKPGGQGDG-PSVPVNSYFQQEFPSLQAAGDQEKSGKDKDTPEEPYGPGPSLR
PQ-NVASWREGGGKNLNTPNSPTDQEVKPVAQEDGNTA-GPVEQNDVPKAAEK---K-EI
-RVPQPPQPKLNGQQQPAVSSQYKAMMPPY---LCNQYPRMAYP-AMQGPSRFPGS-SES
GRGPRGRG--PSWCSEPVERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLN
FSDDDEQGGIQKEKRESSGEQMPSKDSECADGQKEAEERSSNKPST------QAAPQSPG
ARGPYGKSTPF-DQERGGS-----ALH-----PK-SVQQHPP-PDRQAGPGRQGPLPPK-
LVPDEDEIWKQRRRQQAEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCVT
KPSREDPLKERDREREREKERREEREREQ----EREKEQEREKEKEKEQEK--EIEKEE-
---------------------------KAQEQEIQREAEKE-E------------KEE--
-TEEKPDPVPPEPQEPVLAPVI-EKQ----------------------------------
---------------------------------ESESSSTKEEKEGQPIFTQQDSVRNEK
ERSQVDHESELDSGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQ--------Q
QGVLPPSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQPYMDPRMMSGR
PAMDMPPIHPG--IMPPKPLMRRDQLEGSATGSDSFEHIARSAREHTVPLSEPRMRWGSD
PYPHAEPQQASTPPKVLEEPEDLRPEAHLEEEPIAV---TAAYPVE---HSQLDSHQKTD
FFREPDDVDVQKFPIRSLEEVQPLQTD-TPTPAVSFEVADENIIHSAQEELVPV--GESH
SALKRSVSHGSSHSLKSEEQKNE-TIPNVPKISSRYAETKEP-VERSEIKPKKEGFMSN-
--RISEGPKSEKPFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQR
EEREQRKDKEGEKTPNEKAGKSEKTEKKEQVQPSPPQSEPEKPPA-DS--VAPP------
-------KKIVQETAL-ISESTDSSQAESTLKPV-----PQQPAPGQ-PPAVQQPSPAVQ
PPPVQ----QPVNSVKEEKQPEKVAGKEHV-VEKPRLETRP---------VRRE--AGLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHNRDYPHYRETKP
RADHVP-SGPLRQREESETRSESSDFEIVPKRRRQRGSETDSDSEVHESASDTLLSDKDS
LSKGKHPKREERADSKKPP-KPLLSFKPENNVRVDN-RSLEKTYLRGDEENKPKPGFLPK
GEPSRRGRG--GMYRRGGRDPGGRPPRPSTLRRPGYRENQWNPRQMETIKPE---EEEPP
RRHEHYGPVPMDKR-PPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKIN
EAATSLPANATV---VNAANEASSAALEISGSKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKMADLTT-----QVVAKAGENVLAPKREISKRSFSSQRPGVDRQNRRC-NNG
PPKAGRNFSGPRGERRS-GPPLRSGKRGPFEDQAGSITAVDPTISNSLHQ----------
EEVGSAAMPKTSKDASGKKREEPKLGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDFPSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKSLGEK----GR-GQNSK
LPPRFAKAQAQAQAQVQQPQSASQPRSQPQVSVQPQSQ----------TTGGPSS-TEYA
A--------TGKALQNAQAHPALGSEL---------------------------------
------------------------WENKVASTAVVND-----ISKKCKWYLWIFCLEGIE
ISNILECKESS--HIAHKY--AVMKCSA-----------------RLLSCSLPD------
-SLEILFAASIT----------F--TVPS---------YHWFPSWVSLSNLCV-------
------FSNMLIRPIEVDF-----KEFPVKSRNGDLDSNVFNS-------------IVFS
GFLVGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQESGVELGIETIQFGAPASSGSD
SEVGPVLSEKPTDKIPEPKEQRQKQPRAGPIKAQKLPDLNPVENKEYKPGPIGKERSLKN
RKVKDAQQ-GEPEVQEKPSTTAVRSPDPVSTKETKAANELSTEIGTMISVSAPEFGTNTK
ESVTDYTTPS-SHPNTVAASSTKMEETLVTNVPL-PHTLPLPRRETLQQSSSLTPVSPAT
VDLTLKMESARKAWENSPGMGEKGSPITSTASPIAGGTS-----GSSSSSSGPSSATYSS
FSSASMPPIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTN-SL
ASASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFSTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRS
QQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARATLTQASSLYSGQVQQPGQSNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TGQPLIALPQSLQPPLQHAPPQAQAQNMSRPAQVSQPFRGLIPA
GAPHSMIAATGKMSEMDLKAFGSGID-IKPGTPPVTGRSTTPTSSPF-RAASTSPNNQSN
KMNSIVYQK-PFQSAAPPLRMTQ-PFPAQFAPQILSQPNLIPPLVRAPHTNTFPTPVQRP
PMALASQMPPQLTTGLMSHP-----------RLPHVARGPCVSLPGVRGPQAQAAMKAEQ
DVKAKQRAEVLQSTHRFFSEQQQQQS-KAIGG-KVHKADD-SGSKPSEAMPDAPGVCPDK
AEDKPAPVPAA-------APKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKSAG--SPLTSDQDEKLSG-QDESTA-GTSDQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPPLASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPPWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQGSKAPENTENRKEADETCNTKS----SSQIPTQPSV--
SKGPYGKGPSF-NQERG---P-SSHLPP---PPKLLAQPHPP-PDRQTVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKE----REREKELEREQERE----------------------REKE
KQRE----LEKERKQEKEKELE-QQQEKEK--ELQKIKE---QE----KECELE---K--
-KEREKVEEKIEHKEPTLEPM----V----------------------------------
---------------------------------EKPESETNCNKEDDPVFTRQDSNRSEK
ETTQVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRREQMEGSPNSSESFEHIARSARDHAISLSEPRVMWGSD
PYPHTEPQQATTP-KATEEPED--ARPEAPLDQEQI---TTAYPVE---QSQLEVHPKAD
FVRESSEMEVQKFLSRSVEDVRPRHTD-TVSQSACFDVPDQKTVSTPQEERISA--VESQ
PARKRSVSHGSNHTQKSEEQRSD-PSASIPKVTSRCMDSKEP-AERTEEKPKKDGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEKV-VKPEKTEKKDPIPPVPPPAAP----V-QPQSVPLP------
-------PQPELEKFP----STET--SALVLKPPQDAEKPSEPVSS------VEVEPVAK
TVNQQ--TITAPTV-KEEKQPEKLGSKDL--LERPRPDSRP---------AVKKESTL-P
PRTYWKESRDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDTKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKREERSENKKPV-KPQSSFKPENHIRIDN-RPLEKAYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKLD---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPANGTV---NNVVQEPVNPAGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QAVTKTGENALPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNERRSGGPPSKTGKRGPFDDQSAGTTVVDPVNGSSAHHQ---------
EGTPNGTGQKNAKDSTGKKREDPKSGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQAQALAPAPAS-----------------------------------
---TPGLASASAPVPASAPAPVLTSAPAPLPS---SAST-------------PVPPSTSA
P--------ATVTS--SAPAPTPIL--ASASSPASVP-----ILTS--ASIPILAS----
--ALTPTSASAPAPTTSAP--VAPTS-APAT-----PAP-IPTPAPAPASTLVPAS----
----------------ASAPALVPIPAPAPSA----------------------PAQTQP
--PPSIRLPSAQTPNGTEYVATG-KSIQTSQSHGTITTELWDNKVAPPAVLND------L
SKKLGPISPPQPPSVSAWSKPLTSFGSAASSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEIVPVLSEKTTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDSVTTKETKTVSEMSTEIGAMISVSSTEYGANVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSAPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFTSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGS-KAPKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDENYGPGPSLR
PP-NVACWRDGGKAAG--SLSSSDQDEKLPG-QDESTA-VTSEQNDILRVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNENKKEADEVSNTKS----SSQIPAQPPV--
AKGPYGKGPPF-NQERG---T-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKE----REREKELEKEQEQEREKERE--KERERQQEKEKELEKEQE
KQRE----MEKERKQETDRELE-RQKEKEK--ELQKIKE---QE----KECELE---K--
--EREKLEEKIEPREPNLDPT----V----------------------------------
---------------------------------EKQESENSCNKEEEPIFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--IRPEAALDQEQI---TAAYSVE---HNQLEVHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-TSNQSGCFEVPDQKTLSTPQEERISA--VESQ
PSRKRSVSHGSNHTQKPDEQRNE-PSASIPKVTSRCIDSKEP-TERPEEKPKKEGFL---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKAE---KVTEKVVVKPEKMEKKDLLPPAPPPQPPAP--I-QPQSVPPP------
-------IQPEAEKIP----SPET--ATLAQKPSQDTEKPLEPVSS------VQVEPAVK
TVNQQ--TVAAPIV-KEEKQPEKVTSKDLV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPI-KPQSSFKPDNQVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPPYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENILPPKREIAKRSFSSQRP-IDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTTGVDFVNGSSAHHQ---------
EGVSNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNMNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSPSIPPLASAPLPPSTLASASAS----T--SAPVPA------
-TLTPVPASTSAPVTASTLAPILASTSAPVQA---SPLAPV---SASASVSASAPASTSA
AA-I---TSSSAPA--SAPAPTPIL--ASVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPASAPAASSP--AAPIITAPAV-----PAS-A----PAASVSLVPASASAP
APAPT----------------PVSASTPAPSAPAQTQAQTHKPVQNPLQT--ASQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVIPVLLEKSTDKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKASPAAVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNSK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTIPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSTSGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQPQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPASVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGSGWASKQEPHEEEXXXXXXXXXXXXXXXXX----XX
XXXXXXXXXXXXXXXXXXXIQVNSQFQQEFPSLQAAGDQEKKE--KESNDDSYGPGPSLR
PP-NVACWRDGGKSAGSP---SSDQDEKLPG-QDDSTN-GTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QPGGLPSQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-EQGSKSSENTENRKEADEGCSPKPS-------QAAAQLPA
TKGSYGKAPPS-NQERG----LSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEGEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKRAIVE
KQAPPEELREREREKELERE----------QEQEREK----EREKERQQEKERELEKEQE
KQKE----TEKERKQEKEKELE-WRREKEKDLEKMKE---------QEKKCELE------
-KEKEKVEEKTELKESTIEPV----V----------------------------------
---------------------------------EKQENENICNKEEEPLLSKQSSSRSEK
EPAPVAHEAEAESGPQPRSEVLPGHFKQIQKSVPPRFQRQQQ----QQWQQQQQ---QQQ
QGVLPQTVSSQPSSGAVPPPAHRPLYQAMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAVDIAPIHPG---MPPKPLMRRDQMEGSANNSESFEHMARSPRDHATSLSEPRVMWGSE
PYPQAEPPQGSPP-TAAGESES--GRPEATQDQEQI---TAVYPGE---HSHSESHPKAD
FVGESNETETQKSLSRSVEDIRLHHTDAS------DQSVDPKTLSTPPEDRVSA--VESQ
PTRKRSVSHGSNHTQKPEEQRSE-PSVSIPKASNRCIDSKEP-AERPEDKPRKEGFI---
--RSSEGPKPEKLYKSKSETRWGPRPNSSRREEGTDRPVRRSGPIKKPVLRDMKEERELR
KEKEGEKVEKGL----EKVIKVEKTEKKDLPPPLPPAPV-------QPQSVTPP------
-------TQPEPEKCS----S--TEISALTQKASQDIEKPLEPVSS------VQVEPAVK
TVNQQ-N---AAPVVREEKQPEKIVSKEAV-VERPRPDSRP---------VVRKES-ALP
PRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPPYRDSKP
RTEHVP-SGPLRPREESETRSESSDFEIVPKRRRQRGSETDTDSEVHESAS-----DKDS
LSKGKLPKREERSENKKPIKPPQSSFKPESNVRLDN-RLPEKPCVRED--DKSKPSFLPK
GEPTRRGRG--GTFRRGGRDPGARPSRPSTLRRPAYRDNQWNPRQAEAPKPE---DGEQP
RRHEQFIPIPADKR-PPKFDRKFDPARERPRRQRPTRPPRQDKPPRFRRLREKEAASKTN
D--RSVSTSGTV---SNAVLEPVNATGDTSGTKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLIA-----QAIVKAGDNGLPPKREIAKRSFSSQRPGVDRQNRRG-NSG
PPKSGRNFSGPRNEKRS-GPPSKSGKKGPFDDQSASNAGVDSVNGGSSHHQ---------
EGTVNGTGQKNSKESTGKKREDPKPGPKKPKEKVDALSQFDLNNYAXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVWNKKNANEK----GR-SQTSK
LPPRFAKKQVAGTQQVPSPASAPVPAPTVVPTPV--------------------------
--------SPAAPTPASTSAPVLTSTSSPVPASV------------------SVPASTSA
TA----TVSSSAPASVSAPAPTTMLA--STSAPAPIP-----ILTS--ASVPILAS----
--ALAPASASPSPPPLPA-------I----------TTP-APVSAPTASVSLTP------
----------------------ASSSAQAATTPAQTQTQTHRPTQNPVQT---TQSS--K
QPPPSLRLPSAQTPNGTDHVNPG-KSIQTAQSHGALAAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSTSS------------------------------
-----------------EKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
ESVTDYTTPS-SLPNTVATNTAKMEDTLVNNXXX-XXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXMESARKAWENSPNVREKGSPVTSAAPPIASGV--------SSSASGPSTATYNS
FSSASMAQIPVASVTPTASLS--GAGTYTTSSLSTKSATTSDPPNICKVKPQQLQTS-TL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFGTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVTQAQELFTSSLQPYRS
QPAFMQSGLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGXXXXXXXXXXXXXXQHSTPQAQAQLSR--AQV---SQFRLPA
GTQHSMLA-AGKMSEMELKAFGSGID-MKPGTPPIGGRSTTPTSSPS--ATSTSPNSQSS
KMNSIVYQK-QFQSAPPTVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQS---KQIGG-KAQKVDS-DSSKPPETLADPSGVCQDK
IEEKPSPAPTI-------ASKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQGD---------------------------------------------
---DVACWRDGGKSAG--SPSSSDQDEKLPG-QEESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQTALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSGE-DQVSKTSENTENRKEADEVCNTKSS----SQISAQAPV--
AKAPYGKGPSF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAIPGRPGPFPAKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIREREREKE----REREKELEKEQEQEREKERE--KERERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQREKEK--ELQKIKE---QE----KACELE---K--
--EREKVEEKIEPKEPALEPV----V----------------------------------
---------------------------------EKQGSETNCNKEEEAVFTRQDSNRTEK
EPTPVTHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QSVLPQTVPSQPSSGTVPLPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSTRDHAVSLSEPRVMWGSD
PYPHAEPPQATTP-KATEESED--VRSEAALDQEQI---AATYPVEHIEHSQLEAHPKTD
FVRESSETEVQKFLSRSVEDIRPHHTE-SNNQSACFEVTDQKTLSVPQEERISA--VESQ
PARKRSVSHGSNHTQKSEEQRNE-PSASIPKVTSRCIDSKEP-AERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPLRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KVTEKV-VKPEKMEKKDLLPPPPPPAPI------QPQSVPSP------
-------IQPEPEKFP----STET--STLAPKASQDTEKSLEPISS------VQVEPAVK
TVNQP--TVAAPIV-KEEKQPEKVISKDFV-IEKPRPDSRP---------AIKKESTL-P
PRTYWKEGRDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREDRSENKKPI-KPQ-TFKPDNHVRIDN-RPLEKPYVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTV---NNVVQEPINTVADISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----PTAVKAGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGK----------------------------------
----------------------------------------------RVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQAQSLASVPTLASVPVPPSSSA----PGPAST--S----AP-V-PA
LASAPVLASASVPAPASASAPVPPS-----------TLAPI---SAAT--SAPAPASTSA
TA----TASSSAPA--LVPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAVSVP--AAPVISAPAA-----PAS-A----PTASVPLAPASAP--
--------------------APAPTPTPAPTVPAQTQAQTHKPVQNPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVAPG-KSIQNPQSHGTLTTELWDNKVAPTAVLND------I
SKKLGPISPPQPPAVSAWNKPLTSFGSAASSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NDVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPAMVRSTDTVTTKETKSVSEMSTEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPVAGGV--------SSSASGPSTASYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATAGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQ-TQPKPAVPAPPEAAP
VAKSWANTKPSGQDG--PALPVNSYFQQEFPSLPAAGDQEKSGKEKDASEEGH--GPSLR
PQSRCTSWRENGNSNS--PNSPTDQEAKALGQEDGSA--TPAEQSDGQKATEKRDAR---
--LPQIPQPKMNGQQQPPISSQYRAMMPPY---MFNQYPRMAYPPSIQGPTRFPNS--EP
SRGPRGRGP-PSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLN
FSDDDEQGSSQKEK-ESGDEQTPSKDSQSPDTQKEAEEQTNAKSAT--------QASAAA
TKGSYGKNSQLDQERGGPPLHPKSILPP---VRKILILQHPPPPDRQLGPGRQGPFPPK-
PVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMT
KPSREDPLKEREREREREREREREREREREREREREREKEREREREKAKEQEREKEKENE
REKE-------EKEKEKEKE----------------------------------------
--EEKPVHEAPEPVEPVVTPVV-EKQESESRNN---------------------------
----------------------------------------KEEKEEQAIFTRQDSGRNEK
EISQVAHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQ-------QQ
QGVIPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDMPPIHPG--IMPPKPLMRRDQLEGSATSSDSFEHIARSAREHAGPLSEPRIMWGSD
PYPHAEPQQASSPPKVLEEPDNLR--SEAHLEQERVAVPAAAYPVE---HNQLDSHPKPD
FFREPGEVEVQKFPSRPLEDAQSLQTD-TSNTKVNFEGIDENVSRSSAEELMPV--GESH
SSLKRSISHGSSHSLKSEEQRIE-TTANIPKISSRPVESKET-IERIEIKPKKEVLINN-
--RTSEGPKLEKTFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQR
EEREQRKEKEGEKIASEKPSKSEKSDKKEAPQVPVPQTEPETSTSSSAPLAKKIVQ----
------DAAPTPA----SPESTQA---ETAAKV------PVQ-PPTPLPPAILQQPPTQP
VAQQQPQAQQPVTTVKEEKQTEKVVNKEVI--EKPRLETRP---------VKRE--PGLP
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKP
RTEHVP-SGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDS
LIKGKHPKREERADGKKPT-KPL-SFKPENNIRVDN-RSLEKTYMRDD-ENKPKPGFLPK
GEPSRRGRG--GMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQAEIIKPE---DGEPP
RRNEHYGPIPVDKR-PPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKIN
EAVTGSSTTAAV---TNAVTEPSSTALDVSGSKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKTADIAA-----QVAAKAGENTGVPKREIAKRSFSSQRPGIDRQNRRG-NSG
PSRS----QGLGGERRS-GPPPRSGKRGPFEDQTASVPGVDPSNNNSLHQE---------
EGGVNAAGQKSTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEK----GR-GQNSK
LPPRFAKKQQQQAAAAAAQQA---------------------------------------
------------------------------------------------------------
----------QA------------------------------------------------
-QAQTPCAAQTPG-----------------------------------------------
------------------------------------------------Q----PPASVQP
Q-----NQAAGGAAAGTEFTVSG-KVLQNTQAHNGLGTELWENKVPPTAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGAKPGQEGGVELGIETIQFGAPASSGSD
NEVGPVLSEKSTDKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKN
RKVKDAQQ-GEPEGQEKSSPTSVRSPEPVTAKETKATSELSTEIGTMISVSAPEFGTSTK
LSALEFPCLS-ESLQ---SSSVSLNSSLLRTVSVCLPNLKQKHSDTSQQFSSLVDLTAAS
FSASFEMESARKAWENSPNMGEKSSPVTSAASPIAGGSSSN----SSSSNAVPSSGTYSS
FSSASMPPIPVASVTPTTSLS--GTGTYTTSSLSTKTASTSDPPNICKVKPQQLQTS-SL
ASASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRS
QQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLS
QASGLGGSQLLDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQ-----VT
VPLPGSQLSLPNFGS-TAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPA
GTQHSMIAATGKISEMELKAFGGGID-VKPGTPPVSGRSTTPTSSPF-RASSTSPNNQSN
KMNSIVYQK-QFQSAAAAVRMTQ-PFPAQFAPQILSQPNLLPPLVRAPYTNTFPAPVQRL
PIVLHSQMPSQMITGLMSHP-----------RLPHVARGLCGSVSGARGSQAQAAMKAEQ
DMKAKQRAEVLQSTQRFFSEQQQS---KPIGG-KAQKVDE-NGSKPSEAIADSSGVCQDK
AEEKPAPAPPA-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVATPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEPNDDNYGPGPSLR
PP-NVACWRDGGKSAG--SPS-SDQDEKLPS-QDESTS-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQSALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NSSE-DQSSKASENTENRKEADEVCNTKSSSQI----PA-QPL--
AKGPCGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRLGSFPPKQ
QVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIRGKEREKE----REHEKEHEKEQEQEREKERE--KERERQQEKEKELEKEQE
KQRE----MEMERKKEKEKELE-RQREKEK--ELQKTKE---QE----KECELE---K--
--EKEKVEEKTEPKEPTLESM----V----------------------------------
---------------------------------EKQESENSCAKEEEPVFTRQDSNRGEK
EATPVAHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQTSSGTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPMHPG--MIPPKPLMRRDQMEGSPNSSESFEHMARSARDHAISLSEPRMMWGSD
PYPHAEPQQATTP-KATEEPES--GRPEAALEQEQI---TTAYPLE---HSQLDVHPKSD
FVRESNETEEQKILSRSVEDIRPHHTD-TNNQSACFEAPDQKALAIPQEERISV--VDNQ
PARKRSVSHGSNHTQKPEEQRNE-ASASIPKVTSRCVDAKEP-AERLEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KVTEKV-VKPEKTEKKDLTSLPPSPPAP----I-QPQSVSPP------
-------VQPEPEKFP----STEA--STLAHKPSQDTDKSLEPISS------VQVEPAVK
TVNQQ--TVTAPTI-KEDKQPEKVTSKDPV-IERPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVS-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPI-KPQSSFKPDNHIRIDN-RPVEKPYMRDD--DKSKPGFLPK
GEPTRRGRG-GGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKPE---DGEPP
RRHEQFIPIPADKR-PPKFERKFDPARDRPRRQRPTRPPRQDKPPRFRRLREREAASKTN
E-V-AVPTNGTI---NNVAQEPVNTVGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLSA-----QTVAKAGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPPKSGKRGPFDDQSAGTAGVDLANGSSA-HQ---------
EGAPNGTGQKNTKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-NQTSK
LPPRFAKKQATGTQQAQSPASAPAPPSPSAPVP---ASSAPILASA--SAPVP-------
-------TSTSASVSTSTPAPVLTSTSVPVSA---STSA-------------PVSASA--
--SA---TATTSSA--STPAPTPIL--ASVSTSASVP-----ILAS--ASIPILAS----
--ALASTSAPTPAPAVSAP--ASPVISAPAA-----PVS-A----PAASVPLAPASAPGP
APTPS----------------------LASTASAQTQAQTHKPVQNPLQT--TAQSSKQP
--PPSIRLPAAQTPNGTDYVATG-KSIQTPQSHGTLTAELWDNKVAPTAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSAASSEGTKNGQEGGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKPADKTPEPKEQRQKQPRAGPIKAQKLPDLSPIENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKSSPAAVRSTDPVTTKETKAVSEISAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------ISSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFSAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYSTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPTQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDGSDSSKPPDTLTDPPGVCQEK
AEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEEAKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQNTKAKDGK-KYATLSLFNTYKGKSLETQKTT--ARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSHFQQEFPSLQAAGDQEKKE--KESVDDSYGPGPSLR
PP-NVACWRDGGKSAS--SPLTSDQDEK-SG-QDESTT-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPSY---MFQQYPRMAYP-PLHGPMRFPPSLTET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NNSE-DQGSKASVNTENRKEADEVFNTKS----SSQIPAHPSV--
AKGPYGKGPPL-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPPKQ
QVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVD
KQPSPEEIREREREKEREKEREREKELEKEQEWEREKERE--KERERQQEKEKELEREQE
IQRE----MEKERKQEKEKELE-RQQEKEK--ELQKMKE---QE----KECELE---K--
-KEREKVEEKIEHKEPTLEPM----V----------------------------------
---------------------------------EKPESENSCNKEDDPVFSRQDNNHSEK
ETTQAAHETEPESGSQPRPAILSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSGAVPPPPHRPLYQAMQPHPQHLASMGFDPRWLMMQSYMDPRMISGR
PAMDIPPIHPG--MMPPKPLMRRDQMEGSPSSSESFEHIARSARDHAISLSEPRMMWGSD
PYPHTEPQQATTP-KATEEPED--IRPEAPLDQEQI---TAAYPVE---HSQLEAHPKAD
FVRESSETEVQKFLSRSVEDIRPHHTD-TNNQPACFDVPDQKTVSTQ-EERISA--GESQ
PARKRSVSHGSNHTQKSEEQRNE-PSASIPKVTSRCIDSKEP-AERSEEKPKKEGFI---
--RSSEGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQR
KEKEGEKGE---KVTEKM-AKPEKTEKKEPLPPPPPPV----TPL-QPQSVPLP------
-------PQPEPEKFP----SVETSPSTLVQKPPQDTEKPLEPVSS------VEVEPAAK
TVNQQ--TVPAPTV-KEEKQPEKVISKDLV-TERSRPDLRP---------TAKKESAL-P
PRAYWKEARDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX-XGPLRQRE-EETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERSENKKPV-KPPSSFKPENHVRIDS-RPLEKPFVRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQAEAPKPD---DGEPP
RRHEQFIPMPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTS
E-V-AVPTNGTV---SNVVQEPVNTAGDVSGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QVVVKAGENVLPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQSAGTAGADPVNGSSAHHQ---------
EGAPNGTGQKNSKDSTGKKREEPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGTQQAQLPALALASAPGPGSAS----------APG--SATTSAP-V-PA
STPAPVLASPSAPVPAPSAVPVFTSTSAPLPT---LASA-----------SAPVPASTST
--------TATASS--PAPAPTPILA--SASTPASVP-----ILAS--ASIPILAS----
--ALSPASAPPPATSAPAA--PT---SAPTV-----PAS-IP------------------
----------------APTPALVQVSVPAPTAPAQTQGQTHKPVQSPLQT--TTQSSKQP
--PPSIRLPSAQTPNGTDYVATG-KPIQTPQSHGTLTTELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGGE
NEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKSSPATVRSTDPVATKETKAVSEMSTEIGTMISVSSPEYGTNVK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSMSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPSEQATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQ---------------------------
------------------------------------------------------------
---AKQRAEVLQSTQRFFSEQQQ--N-KQIGG-KAQKVDN-DSSKPPETLTDPPGVCQEK
VEEKPPPAPTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKRKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESIA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAMMPPY-----VSI---MFQQYPRMTYP-PLHGPMRFPPSLSEG
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQGSKASENNGNKKEADEVSNAKS----SSQIPAQPSL--
AKVPFGKGLHLIRFERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENNCNKEEEPVFTRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQVMIKIFYHVSA------AT
ASVLPQTVPSQPSSSST-------LY-QLCSSSQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPAIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQQATTP-KATEEPED--VRSEAALDQEQI---TAAYSVE---HNQLEAHPKAD
FA------EVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLPTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-PSAGIPKVTSRCIDSKEP-TERPEEKPKKE------
------GPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEWEQR
KEKEGEKTE---KVTEKVVIKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKSLEPVST------VQVEPAVK
TVNQQ--PVAAPIV-KEEKQPEKVISKDLV-MERPRPDSRP---------AIKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHVP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKSKPGFLPK
GEPTRRGRR--GTFRRGGRDPGGRPS--------PYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPGRERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTIGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ESRERDEKKNADLNA-----QTVVKIGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLVSAPLPPSTSASVPAST------SAAVP-------
ATLTPVLASTSAPVPASTLVPVLASTSAPVPA---SPLAPV---SASASVSASVPASTSA
VAI----ISSSAPA--SAPAPTPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPTSAPTPAPAASSP--AAPVITAPTI-----PAS-A----PTASVPVAPASAPAP
ATTPVSAPTSA-PPAPAPATTPVSAPTSAPPAPAQTQTQTHKPVQNPLQT--PSQSSKQP
--PPSIRLPSAQTPNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPATLNLNRVSYGF
FFPVGPISPPQPPSVSAWNKPLTSFGSAASSEGAKNGQESGLEIGADTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSAEIGTMISVSSAEYGTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPT
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIG-GKAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVAPPPEIAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--PSSSSDQDEKL-V-QDENTA-VTSEQSDILKVVEK---R-IA
CGPPQ---AKLNG-QQPTLASQYRAMMPPY---MFQQYPRMAYP-PLHGPVRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSSSPKE-NNSE-DQSTKASENTENRKEVDEVSNTKS----SSQTPAQPPV--
AKGPYGKGPPF-NQERG---P-SSHLPP---PPKLLAQQHPP-PDRQGITGRSGPFPPKQ
QVPDDDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVE
KQPSPEEIRERERGKE----QEREKELEKEQEQEREKER----ERERQQEKEKELVKEQE
KQRE----MEKERKQEKEKELE-QQREKEK--QLQNMKE---QE----KEYDLK---K--
--ERE-------------------------------------------------------
---------------------------------------------KEPVFTRQDSNRSEK
ETTQVMHESEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQ----QQQ
QGVLPQTVPSQPSGSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDMPPIHPG--MIPPKPLMRRDQMEGSPNNSESFEHIARSARDHAVSLPEPRMMWGSD
PYPHAEPQPTAEP-KTNEESDD--VRPEVALDQEQI---TAAYSVE---HSQLETHPKAD
FVRESSETEAPKFLSRSVEDIKPHT-D-TNKQSACFEVPDQKTLPSTPEEQIST--LESQ
PTPKRSVSHGSNLSHKSEEQRSE-PSVILPKVTSRCIDSKEP-AERPEEKPRKDSFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREDSNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKVE---KATEKA-VKPEKTEKKDLVSPPSPPVAP----V-QPPSLPTP------
-------VQPESEKFP----STET--STLAQKPSQDTEKPLEPVSS------VQVEPAVK
TVTQQ--TAASPAV-KEEKQPEKAISKDVG-IERTRPDSRP---------AVKKESTL-P
PRTYWKEARDRNWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RTEHVP-SGPLRQREESETRSESSDFEIVPKRRRQRGSETDTDSEIHESAS-----DKDS
LTKSKLSKRDDRSENKKPL-KPQPSFKPENHVRVDN-RPLEKPYIRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPATLRRPTYRDNQWNPRQTEAPKPE---DGEPP
RRHEQFIPMPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAATKTN
E-V-LVPTNGTV---NNVVQEPANTAGDISGNKTPDLSNQNSSDQANEEWETA-------
----------------------VVKAGENVSPPKREIAKRSFSSQRPGIDRQNRRG-NNG
PPKSGRNFSGPRNERRN-GPPSKSGKRGPFDDQSTGTASVDPVSGSSAHHQ---------
EGTSNGTGPKNSKDSTGKKREDTKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANDK----GR-SQTSK
LPPRFAKKQATGTQQVQLPVSALAA----VPAPSST--SAPVLASP--APPVTA------
STATVVVTSPAVLVSAPTQAPVLPSTSVPVPT---ST-------------STPVSSSSAA
-PIT---SSSSASV--SIPAPTPIL--ASVSAPAFRP-----YTYP--ASIPILAS----
--ALVPASAPPPATAVSAS--AVPAVSPPAA-----SAS-------------------AP
APAPAPAPVPVP------APTPA-----------PTPTQTHKPVQNPLQT--S-QSSKQP
--PPSIRLPSAQAPNGTDFVAPG-KSIQTPQPHGSLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNGQESGVEIGIDTIQFGAPASNGNE
NEVVPVLSEKSADKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPASSAVRSTDSVTVKETKAVSEMSAEIGTMISVSSAEYATNAK
ESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPL-PNTLPLPKRETIQQSSGLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSAAPPIASGV--------SSSASGPSTANYSS
FSSASVPQIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPS
LAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTPPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIGGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSTPATVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PMALASQMPPPLTTGLMSHA-----------RLPHVARGPCGSLSGVRGNQAQAALKAEQ
DMKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETLTDPPGVCQEK
VEEKPPPASTI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVSP-AQPKPGVTAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KEANDDNYGPGPSLR
PP-NVACWRDGGKSAG--P---SDQDEKLLN-QDENPA-ISSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQPALASQYRAMMPPY---MFQQYPRMAYP-PLHGPMRFPPSLSET
NKGPRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDEEQGSSSPKE-ISSE-DQTSKVSENTENQKEAEEVRNTKS----PSQTPAQPPV--
TKGPYAKGPAF-SQERG---P-SSHLPP---PPKLLAQQHPP-PDRQPVSGRSGSFPPKQ
QVPDEDEIWKQRRKQQSEVSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKRAIVQ
KQPSPEEMQ---REKE----REREKELEKEQEQ----ERE--REKERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-QQREKEK--ELQKIKE---QE----KESELK---T--
--ERETLEEKIEPKESPLEPV----A----------------------------------
---------------------------------EKQE--------SEPVFTRQDSNRSEK
ETTQVAHESEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQQQQQQ
QGVLPQTVPSQPSGGAGPPPPHRPLYQPLQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPTKPLMRRDQIEGSPNSSESFEHIARSARDHAISLSEPRMMWGSE
PYPHTEPQPATTP-KAPEEPEE--PRPETALEQEHI---SAAYPVE---HGQLEAHPKTD
CVRPPDDTEVPKFLSRSVEDIRPHHTD-TNNQSGGFEVPDQKTLSTPADERIST--LESQ
PARKRSVSHGSSHTQKSEEQRNESPSVSIPKVTSRCLDSKEA-SERPEEKPRKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKLE---KFPEKV-AKPEKIEKKDLPSPPPPPAPIP-----PQPVPPVQ------
-------PEPEKEKVP----STET--SALAQKPSQDTEKPLEPATS------VQVEPTVK
TANQQ--TVVAPTS-KEEKQPEKIISKDIA-TDRPRQDSRP---------VVS---NR-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHARDYPQYRDSKP
RTEHVP-SGPHRQREESETRSESSDFEVVPKRRRQRGSETDTDSEVHESAS-----DKDS
SSKGKLPKREERSENKKPI-KPQSSFKPESHVRVDN-RPLEKPYLRDD--DKSKPGFLPK
GEPTRRGRG--GTFRRGGRDPGSRPSRPSTLRRPAYRDNQWNPRQAEAPKTE---DGETP
RRHEQFIPVPADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKPD
E-V-PVPTSSTM---SSGVQEPVSASGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERGEKKNADLST-----QAVVKTGENVVPPKRDIAKRSFSSQRPGIDRQNRRG-NTG
PPKSGRNFSGPRNERRN-GPPSKSGKRGPFDDPSAGTTGSDSVNGSSSHHQ---------
EGTPNGTGQKNLKDATGKKREDTKPAPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVV
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKSTSDK----GR-NQTSK
LPPRFAKKQATGTQQIQSPVSAATT----APAPIST--SVSIVTPT--SAPAPA------
STLAPALASPSVLVPASTPVPVLNSTSAPAPV---TS-------------TSTTS-----
---T---ASSSPPA--SAPAPTP---------------------VP--SPVPVLAS----
--ALAPTPASPPT--------SVPTPSVPTS-----PA-----PAPTTSVPLP-------
----------------------------PAAAASPSPAQTHKPIQSPLQA--STPSAKQP
--PPSIRLPSAQTSNGTDYVAPG-KSIQTPQSHSTLTAELWDNKVAPPAVLND------I
SKKLGPISPLQPPTVSAWNKPLTSFGSATSSEGTKNNQESSVEIGIDTIQFGAPASNGGE
NEVVPVLPEKS-EKIPEPKEQRQKPPRAGPIKAQKLPDLNLIENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSSPTVRSTDPVSTKETKAVSEMSTEIGTMISVSSAEYSANAK
ESVTDYTTPSSSLPTTVATNSTKMEDTLVNNVPL-PSTLPLPKREAAQQSSSLTSVPPTT
FSLTFKMESARKAWENSPSIREKGSPVTSTAPPLAAGV--------SSSTSGPGPANYSS
FSSASVPPIPVASVTPTTSLS--GAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-NL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---AQIPAFYMDTSHLFNTQHARLAPPP
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQDLFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGSSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLTNFGS-TGQPLIALPQTLQPPLQHSTPQAQAPSLSRPPQVGQAFRGLIPA
GTQHSMMATTGKMSEMELKAFGSGID-IKPGTPPISGRSTTPTSSPF-RATSTSPNSQSS
KMSSIVYQK-QFQSAPAAVRMTQ-PFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRP
PVALASQMPPPLTTGLMSHA-----------RVPHVARGPCGSLSGVRGNQAQAVLKAEQ
DLKAKQRAEVLQSTQRFFSEQQQ--S-KQIGG-KAQKVDS-DSSKPPETRTDPPGVCQEK
VEEKPPPAPAI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

MSEKSGQSTKAKDGK-KYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPP
ANLPSLKAENKGNDPNVNIVPKDGTGWASKQDQHEEEKTPEVPP-AQPKPGVAAPPEVAP
APKSWASNKQGGQG---DGIQVNSQFQQEFPSLQAAGDQEKKE--KETNDDNYGPGPSLR
PP-NVACWRDGGKAAG--SPSSSDQDEKLPG-QDESTA-GTSEQNDILKVVEK---R-IA
CGPPQ---AKLNG-QQAALASQYRAMMPPY---MFQQYPRMTYP-PLHGPMRFPPSLSET
NKGLRGRGPPPSWASEP-ERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLN
FSDDDEQGSNSPKE-NNSE-DQSSKASENNENKKEADEVSNTKS----SSQIPAQPSV--
AKVPYGKGPSF-NQERG----TSSHLPP---PPKLLAQQHPP-PDRQAVPGRPGPFPSKQ
QVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE
KQPSPEEIREREREKEREREKE----LEKEQEQEREKE--REKERERQQEKEKELEKEQE
KQRE----MEKERKQEKEKELE-RQKEKEK--ELQKMKEQ-------EKECELE------
-KEREKLEEKIEPREPNLEPM----V----------------------------------
---------------------------------EKQESENNCNKEEEPVFIRQDSNRSEK
EATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ------QQ
QGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGR
PAMDIPPIHPG--MIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSD
PYPHAEPQRATTP-KATEEPED--VRSEAALDQEQI---TAAFSVE---HNQLEAHPKAD
FVRESSEAEVQKFLSRSVEDVRPHHTD-ANNQSACFEAPDQKTLSTPQEERISA--VESQ
PSRKRSVSHGSNHMQKPDEQRSE-TSAGIPKVTSRCIDSKEP-TERPEEKPKKEGFI---
--RSSEGPKPEKVYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPVLRDMKEEREQR
KEKEGEKTE---KVTEKVVVKPEKTEKKDLPPPPPPPQPPA--PI-QPQSVPPP------
-------IQPEAEKFP----STET--ATLAQKPSQDTEKSLEPVST------VQVEPAVK
TVNQQ--TVAAPIV-KEEKQPEKVISRDLV-IEKPRPDSRP---------AVKKESTL-P
PRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKP
RAEHIP-SGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS-----DKDS
LSKGKLPKREERPENKKPV-KPQSSFKPDNHVRIDN-RLLEKPYVRDD--DKAKPGFLPK
GEPTRRGRG--GTFRRGGRDPGGRPSRPSALRRPAYRDNQWNPRQSEVPKPE---DGEPP
RRHEQFIPIAADKR-PPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSN
E-VVAVPTNGTV---NNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFN
ERRERDEKKNADLNA-----QTVVKVGENVLPPKREIAKRSFSSQRP-VDRQNRRG-NNG
PPKSGRNFSGPRNERRS-GPPSKSGKRGPFDDQPAGTTGVDLVNGSSAHHQ---------
EGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVI
EDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEK----GR-SQTSK
LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAST------SAPLP-------
ATLTPVPAPTPAPVPASTLAPVLASTSAPVPA---SPLAPV---SALASVSASVPASTSA
AAI----TSSSAPA--SAPAATPILA--SVSTPASVP-----ILAS--ASIPILAS----
--ALAPASAPTPAPAASSP--AAPIITAPTI-----PAS-A----PTASVPLAPASASA-
-----------------PAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQT--TSQSSKQP
--PPSIRLPSAQTSNGTDYVASG-KSIQTPQSHGTLTAELWDNKVAPPAVLND------I
SKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGAKNGQESGLEIGTDTIQFGAPASNGNE
NEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKN
RKVKDAQQ-VEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYVTNAK
ESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPL-PNTLPLPKRETIQQSSSLTSVPPTT
FSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGV--------SSSASGPSTANYNS
FSSASMPQIPVASVTPTTSLSG--AGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTS-SL
PSASHFSQLSCMPSLIAQQQQSPQVYVSQSAA---G---------NSFFNTQHARLAPPS
LAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS
QPAFMQSSLSQPS-VVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLG
QASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQ-----VT
VPLPASQLSLPNFGS-TGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPA
GTQHSMIATTGKMSEMELKAFGSGID-IKPGTPPIAGRSTTPTSSPF-RATSTSPNSQSS
KMNSIVYQK-QFQSAPATVRMTQ-PFPTQFAPQAKQRAEVL-------------------
------------------------------------------------------------
-----------QSTQRFFSEQQQ--S-KQIGGGKAQKVDS-DSSKPPETLTDSPGVCQEK
VEEKPPPAPSI-------ATKPVRTGPIKPQAIKTEETKS--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------

Query Results

"ENSGT00530000063496_0"

ENSGT00530000063496_0