Query Results 

---------------------------------MADDRKDDAKAPHWTSPQLTEAS--AH
PHPPEIKDQDGAGEGLVRSANGFPYREDEEGAFGEHGPQGTYSDTKENGINGELSSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKETQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
FTALKMEFHGQQELSSSATEPLDQKTKESEKQSKPGEDVKNAALVSHPETTKISPDEKNV
QDK-EEEKIPPSLFQHTLDASPEDLKQKSEPSLVVPGIDAPAEPPTQKEQKDWFIEMPVE
AKKDEWGLVAPVTPGPLTPMKERDMLEDIPKWEGKQFDSPMPSPFQGGT---FTLPLDV-
------MKSQIV-ATASPFSPVLLQP--DNTKSLEASAPEAAKDT----SLVEEPLKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTEQTPASVATT-SPKDTDTTVTEE--CITDKVSGEEKVALKEESMQEIETAILGGW-E
PTVLEKELQLQFEE----KISIHDKEAVPKESKPH---TLTE--DETGIAHTTTEPPISK
EELKGQEPTTDMLKQDSFPLSLEQGVTDSAMTSKTLETVLTEPCPLSEKSSIQELFEEKV
TDKD-KVEKAGTPASSELDMPFYEDKSGMSKYFETSTLKEEVTKS--LQPSSDYYELSDT
RESSH-EPFDSLSPMYK----NGDEGIQTEKEPQPQATAQETGYSTLAQSYPSE----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKA-EE
KIEE------------AK----------T-TGQENIQADTVCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVGADAEVARRKSVPSETVIEE-STGL-PSVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSTEKEIS-----PHVSGLGREFDQEKKVNDKLDTVLEKSEEHVDSKEHAKT
TEDAAG-------------------RVETLE--LGVTDEQSLA-KELMISKDTSPLVTEK
AE-KGLSSVPEVAEVEPSKKPE-----PGLDFAAEKADQ---GQLDVKISDFGQDTRELT
VVAGVG---VELKLKET-QQDLAASPKVPQEADAFMGVEPGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDDGKKETSPESSLIQDEVAIKLSVE
-------IPCASAVSE-TDLATEEKVDVQMESIQLPEEE----SKETPDISITPSDVTEP
-LAEGIVSKPADA---------PREEEEVEAQG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------ELNVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSVLDADSLWVDTQDDDRSIM---TEQL-------
---------ETVPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAV-----------
----------------------------------------------GETTQTPAVFKQAK
DKVSXGVTRSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
-KVAIIRTPPNLLATPKQLRL-

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2199)

NQPLPDLKNVKSKIGSTXXXXXXXXXXXV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

H

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKA------------------
---------------------------------------

---------------------------------MADERKEEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDKKEKESEKQSKPGEDLKHAALVSQPETTKPYPDEKDM
QGT-EEEKAPLALFGHTLVANLEDMKQKTEPSLVVPGIDLPKEPLTPKEQKDWFIEMPTE
AKKDEWGLVAPVSPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKSEIV-TETSPFAPAFLQP-DDKKSLQQTSGPATAKDS----SEIEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEVPPSEAMT-LPKDTHIPVVEE--HVMGKVLEEEKEAIKQT-MQQKDIFTPSGQ-E
PTLTEKEPELKLEE----KITISDKEAVPKETRPP---KLAD--EETGIIQTSTEHTFS-
-EQKGHEPTTDMLKQDSFPVSLEQAVTDSAVTSKTLEKAMTEPSALIEKSSIQELFDMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IQPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQTYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVEGKEE-E
QMEK------------VK----------V-TGEENTQVETTCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIAKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-LPISGDKSGLSKEFDQERKASDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--KVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AA-KGLSSVPEVAEVEPSKKAE-----QGLDFAANKAVQ---GQIDVKISDFGQMASGLN
IDARRA---TELKLEAT--QDMTPSSKAPQEADAFMGVEPGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCPPTVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-VHEAIVSEPAEV---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGASGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALDQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESAVAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADEQKDEAKAPHWTSAQLTEAS--AH
PQPPEIKDQAGAGEGLVRSANGFPYREDEEGAYGEHGPQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTIPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPDHQELTSSAAEPLDKKEKESKMESMPGEDFKHAALVPQPDTTQTFPDTKNM
QGA-EGEKAPPALFGHPVGATLEDMKWKTEPSFIVPGIDLPAQPPSPREQKDWFIEMPVE
TKKDEWGLAAPMSPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFQPGS---FTLPVDV-
------MKNEIV-TEASPFEPGFLQP-DNKKSLQEISGPVTAKDS----SKVEELQKDEP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAETAASEAIT-LPKDPHVPVLEG--YVIEKVLGEKRGT-------------PSGQ-E
PTLTEKELQPKLEE----KTCVSDKEAVPKEHEPS---KLRD--EETAIIQTATEHTFLK
ETPKSQEQITDMLEPGTFPVGLEQAVTDSTMTLNTLEKVSTEPAALYEKSTLQELFQEKV
ADTDSNVEGVRDAPSAEIGMPFYEDKSGMSKYFETSALKEEVMKN--IQLASDYYELSDT
RESAH-ESADTISAMLE----SDDKEFQVGKESQPSAPAQGAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKAPCFPIESKEEEE
KTEE------------EK----------A-TGQENIQVETSCESPFVAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVT---DENHTIVKT
DSHLEDLGYCVFNKYTVPLPSPVQDSENLSGESGCFYEGSDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKETS-----SPTSGLVREFDQERKANDKLDTVLEKSEEHADSKEYAME
TEEAG-----------------G--KVDTFG--LGLMYKPTSA-KELTVSKDAAF---EK
AE-KGLSSVPEVAEVEPSKKTE-----QGLDFAATKADQ---GQLDVKISDFGQITARLN
VDAGEA---AELKLKGA--QELALSSKAPQEADVFLGVEASHMKEGARVSEIEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEAKKEMSLESSLMQDEIAIKLSVE
-------IPGPPAVSE-ADLAAAEQADVQMEFIQMPKEE----SKEAPDISITPSDVTEP
-QLEAVISEPPEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-QRR
PSPHEEE----------------------------ELEVAAEAQAEPKDGSPEAPASPER
E-A-VLLEYK-TETYDDYKDETTIDDSVMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATG-----------
----------------------------------------------GESTQAPSAFKQAK
DKVSDGITKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSISSSVRRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
SHPPEIKDQGGAGEGLVE------------------------------------------
------VSARIVQVVTAEAV-----------AHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQESTPSAAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTTTYPDKKDM
QGT-EEEKAPPALFGHTLIASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TETSPFAPAFLQP-DDKKSLQQTSGPATAKDS----FKIEEPHEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPLSEAMT-LPKDAHIPVVEE--HVMGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKEPELKLEE----KTTISDKEAVPKESKPP---KPAY--EETGIIQTSTEHTFS-
-EQKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDIPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-THISGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPDITEVEPSKKVE-----QGLDFAV-------QGQLDIKISDFGQMASGLN
IDDRRA---TELKLEVT--QDMTPSSKALQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCPPVVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LREAIVSEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHRGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2272)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_3_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

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-------------MAEDRKDE--------AKAPHWTSGQLTEASSH---PHSP-------
---------EIK-DQGGA-----S-------------------AGLVRSANGFPYRE---
--DEELRLGSHEQPGTYAQTKENGINGELSSGSRETAEEVSARIVQVVTAEAVAVLK-GE
QEKE-AQHKDQPGSLPL--AVEESA-NLPPSPPPSPASEQTGVLEEAAG-----------
----------------------------------------------GETNQAPAVFKQAK
EKLSDGVSKSPEKRSSLPRPSSILPPRRGVSGDRDREENSLSLSASLSSSVRRTTRSEPI
RSRTGKSGTSTPTTPGSTAITPGTPPSYASRTPGTPGTPSYSRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRVINQPLPDLKNVRSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSM
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELSSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHHQQELTSSAVEPLDKKEKESEKQSKPGEDLKHAALVSQPETTKTYPDEKDM
QGT-EEEKA-PALFGHTLVANLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKSEIV-TETSPFTPAFLQP-DDKKSLQQTSGPATAKDS----SEIEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEVPPSEAMT-LPKNAHIPVVEE--HVMGEVLEEEKEAIKQEIVQQKDIFTPSGQ-E
PTLTEKEPELKLEE----KTIISDKEAVPKETRPP---KLAD--EETGIIQTSTEHTFS-
-EQKGHEPTTDMLKQDSFPVSLEQAVTDSAVTSKTLEKAMTEPSALIEKSSIQELFDMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IQPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYQSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QMEK------------VK----------T-TGEENTQVETTCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSEMVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-LPISGDKSGLSKEFDQERKASDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--KVETFG--LGVTYEQALA-KDLSIPTDASS---EK
VE-KGLSSVPEVAEVEPSKKAE-----QGLDFAANKAVQ---GQIDVKISDFGQMASGLN
IDARRA---TELKLEAT--QDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCPPAVSE-ADLATDEKADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-VHEAIISEPAEV---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGASGARE
-EFVETCP---GEHKGVIESIVTIEDDFITVVQTTTDEGESGSHSVRFAALDQPEV-ERR
PSPHDEE--------------------------EFDVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESAVAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSMSSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSAERE
TA--EEVSARIVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--
XXXXXXXXX---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------XXL
LTASKMEFRDQQELTSSTAEPLDKKEKEPEKLSEPGEDLKHAALVSQPETAKTSLDKKGT
QDT-E-EEVPPALFGHTLGASVEDVKQKTEPSPAVPGIDLPAEAPAPKEQKDWFIEMPVE
AKKDEWGLAAPISPGPLTPMREKDVLDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDI-
------MKNEIF-TQPSPFAPALLQP-DDKKSLQEISGPATAKDS----AKVEEPPKDKS

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DTMAEAPFPEAFT-LPKDAHIPVVGK--HVVEQDLEEEKEAINQESMYKKETSAPSEP-D
TTLTEKEPPLKLEE----KAIIS-KEAVPKENDPK----PTD--QETSVLQASTEHTFSK
EELKGKESATD-MKQDTCPVSVEQ---DSLTTPKTLEKVMAEAAAVSEKSTTQELFKETV
ADQDV----RGAATSSELDMPFYEDKSGMSKYFETSALKEEVTEG--IQPGSDYYELSDT
RESAQ-ESTDTISPIHK----NGDKEFEAGKEPQPSASAQEAGYSTLAQSHPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPCFPAESKEE-E
QTEE------------EK----------A-TGEPNTQVDTSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVGADAEVARKKSIPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGDSGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKEAS-PHIPGDKSGLGREFDQERKVNDKLDTVLEKSEEHADSKEQAKE
IE--------EAV---------D--KVEPFG--LES-------------------KDAEK
AE-KSLSSVPEVGEVEPLKKAE-----QELDFAAKKADQ---GPLDVKISDFGQMASGLN
VDAGKA---TELKLEAT--QDLTPSSKAPQEADVFMGVEPGHAKESVKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEIAIKLSVE
-------IPCSSAVAE-ADLATDEKADVQMEFIQLPTEE----SKETPDISVTPSDVTEP
-VLEAVVSEPAET---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGIPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHEEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSILDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESTQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSTQLTEAS--AH
PHQPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHESQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEDTANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFQDQQELTPSTAEPLDKKEKESEKQSKPGEDFKHAALVSQPETTKTYPDKKDM
QGT-EEEKVSPALFGHTLFTSLEDTTQKTEPSLVVPGIDLPVQPPAPKQQKDWFIEMPME
AKKDEWGLVAPISPGPLTPMREKDVFEDIPKWEGRQFDSPMPSPFQAGS---FTLPVDV-
------MKSEVI-TETSPFAPAFFQP-DDKKSVQETSGPPTAKDS----SKVEEPHKDTT

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DRMAEAPVSEAIA-LPKDAHIPVVEE--SIMEKIFGGEIGAINQESVQKKDTSIPSGP-E
PTLTEKEPQLKLEE----KTTISDKEAVPKESRPL---KLAD--EETGIIQTSTEYAFSK
-EQEGQEFTTDMLKQDSFPVSLEQAITDSTMTSKTLGKVMTEPAVLTEKSVTQQLFEEKV
TDKANRVEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEVSKS--IQPGSDYYELSDT
RESAP-ESIDTISAMHK----NGDKGFQA-EDSQPSALAQEAGYSTLAQSYPPE----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKGPCFPVESKEE-K
QIEK------------EK----------A-TGEEVTQVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVSRRKSVPSATVVEESSTGL-PPVT---DENHIVVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKARRDLATDLSLIEVKLA
AAGRVKDEFSAEKEAS-PHISDDKSGLDREFDQERKVNDKLDTVPEKSEELIDSKEHAKK
TEEAV-----------------D--KVETFD--LGITYEQASA-KELTMSKDASS---EK
AE-KVLSSVPEVAEVEPSKKAE-----QGLDFAAQKATQ---GQLDVKISDFGQMASGLN
IDAGKA---TEFKLDTT--QDLTPSSEVPPEADAFMSVESGHMKEGAKVNETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKEISPESSLIQDEIAIKLSVE
-------IPCPPAVSE-ADLVTDERADVQMEFIQLSKDE----SKETPDISITPSDITEP
-LLGAVVSEPAEA---------PSEEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPDV-ERR
PSPRDEE--------------------------ELEIEEAAEAQAGPKDGSPEAPASPER
E-EIALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------GESPLAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKASHWTSAQLTEASASTH
PHPPEMKEQGVAGEGLVRNANGFPYQEDEEGAFGGPRSQDTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPTALPLAAEETANLPPSPPPSP--
ASEQTIPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSSAEPLDTKGKESELICKPGEDLKHAALVPQPETTKTSPDKKEI
QGT-EGEKAPLALFGHTLGDSQEDTKQKTETSVVIPGIGLSAESPAPKEQKDWFIEIPVE
TKKDEWGLAAPVSPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFQGG----FTLPLDV-
------MKNEIA-TGASPFAPVLLQP-EDKKSLQEATDPATAKDS----ATIEESQKDKT
E

PF08377 // ENSGT00530000063491_1_Domain_0 (602, 1964)

KVAETPEAII---LPKDAYGLVMEG--YVVEKDLGEEREGTNEE---KKETSIPSGQ--
------EPQPKHEE----QVIISDKEVTLKDHEPP---THRD--EETGVIQSSVELSFSK
EGPKSQAQSTDIFNQDSFSAGLESTFTDSVLASKTLEKVTTEPATLSEKSAAQEFSEEKV
AVKD-KVEGVGTAASAEVGMPFYEDKSGMSKYFETSALKEESIKS--IQLGSDYYELSDT
RERAQ-ESTDTISTATQ----NDDKGLQEGKESQPSVPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPCFPIESKEEEE
KIEE------------GK----------ATAGQENTQVETSSESPFLAKDYYKNGTVMAP
DLPEMLDLTGTRSRLASVSADAEFARRKSVPSETVVEESSTGL-PPVT---DANHVIVKT
DSQPEDLGYCVFNKYTVPLPSPVQDSDNLSGESGSFYEGADDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKEAA-PSTSADKSGLGKEFDQDRKANDKLDTVLEKSEEHTKETEEAG-
----------------------G--NAEMFG--LGMTYEQVSTTKEPTIAKHSSP---EK
V-GKGLGSVPEVAEVEPSRKAE-----QELDLA---------DQLDVQISDFGQMAAGLS
VEAGKA---PELKLEAA--QELTPASKAPQAADAFLGVELGHVKEGAKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTLESLKPDEGKKETSPESSLIQDEAPIKLSVE
-------IPCPPAVSE-AELAADDRADVQMEFIQLPKEE----SKETLDTSVTPSEVTPT
-QVEAIVCEPAEA---------LSEEEEIEARG---EYDKLLFRSDTLQITDLGIPSSRE
-EVVEACP-GPGEHKGVIESVVTIEDDFITVVQTTTEEGESGSHSVRFAALEQPEVE-RR
PSAPEED--------------------------QFQVEMAAEAQAERRDGSPGR-----E
E-VVAYSEYK-TETYDDYKDETTIDDSILDADSLWVDTQDDDRSIM---TEQL-------
---------DTIPKEEKADKEVRR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
-----------------------------------------------ESTQAPSAFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EEHSFSLNSSISSAARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRT---PGTPKSAILVPGE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSTQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQSTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
FPASKMEFHDQQELTPSPAEPLDKKDKESEKQSKPGEDLKHAALVSQPETTKTSPDTKDM
QGT-EEERAPPTLFGQPLGAGLEDMKQKTEPSLVVPGIGLSAEPPTPKEQKDWFIEMPTE
AKKDEWGLAAPISPGPLTPMKGKDVLEDIPKWEGKQFDSPMPSPFQAGS---FTLPLDV-
------MKNEIV-AEASPFAPAFLQP-DDKKFLEETSGPAPAKDS----SKAEEPPKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAEAPASEATT-LPKDALIPTVEE--GVPEKVLGEEKGAIKPESAQEKEQ-------E
ATPTDKESQPKLEE----KTTISDKEAMPKDSEPP---KLTD--GETGIIQPCMEHALSK
EEQKGQEPTTDAL---LFAVSLEQAVTDSAMTSTTLEKVVTEPAAASEKSATQDLFEEKV
VDKDTKVEGAGAATSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPASDYYELSDT
RESAL-ESLDTVSPVCK----NGDKELEAGKEPQPSAAAQEAGYSTLAQGYPTD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QPEG------------EK----------A-PGEDNAPVEPSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEEASTGL-PPVT---DENHVVVKT
DGQLEDLGYCVFNKYTVPLPSPVQDSENLSGDSGSFYEGPDDKMRRDLATDLSLIEVKLA
AAGRVKDELGAEKEVS-PHVPGDKPGPARESEQDRKASEKLDTVLEKSEEHADAKEHSRP
AEEAS-----------------D--KADTSG--LGAI----SE-HPPTAAKDASPPAAET
AE-KGLSSVPEVGEVEPSRKAA-----PELDFVAKKADQ---GHVDVHISDFGQMAAGLT
LDGGQE---TELPPEVG--QDLAPSTL------APPGVEFGPVKEGARASETEIKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPAVSE-AELAPDERADVQMEFIQQPQED----SKGTPDISVTPSDVPEQ
-VPEAAGIEPAEA---------RSEEDEIEAQG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGAHSVRFAALEQPEV-ERR
PSPRAGEELH---------------------LKELHVDEAAEAQAEPRDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTATG-----------
----------------------------------------------GESTQASSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------AEETANLPPSPPPSPSP
ASEKTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFLDTQELTPSAAEPLGKKEQESEKEKKPGEDLKNAALVSQPETTNISPDTMDT
QDT-EEEKTLPPPFGHALGASLEDVKGKTEPSPVVPGIGLSAEPLTPKEQKDWFIEMPTE
AKKDEWGLAAPVSPGPLTPMKEKDVLENIPKWEGKQFDSPMPSPFQGGS---FTLPLGV-
------IKNEIV-AGSSPFASALLQL-EDKKFQDETSGLPAAKDS----ATTEAPHEEEP
DRMAEAPVSAMTPSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXX--XXXXX-X
-XXXXXXXXXXXXX----XXXXXXXXXXXXXXXXX---XXXX

PF08377 // ENSGT00530000063491_1_Domain_1 (703, 1082)

ADEKTGPVQSFVEHAFSG
EQ----------KTQDSFPGS--------------LDKGMIEPVKLSEKSAIQDLFEENI
AEQDNNVEGIEAAASAELQMPLYEDKSGMSKYFETSALKEEVTKS--LQSASDYYELSDT
RESAEEESLDTLSPMYK----EGDRKFQAGKESQPSAPAQDSGYSTLAQSYPSE----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRVHDLSPLASDILTNTSGSMDEGDD-YLPATTPA-EKAPCFPIESKEQEE
QVEE------------KA------------ARDVNTQPEAPCESPFLAKFY--NGTVMAP
D

ENSGT00530000063491_1_Linker_1_2 (1082, 2179)

LXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXX-------XXXXX
XXXXXXXXXXXXXXXXXXXXX-XX--XXXXXXXXXXXXXXXX-XXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXX-----X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-X-------XX---------X--XXXXXX--XXXXXXXXXX-XXXX-----XX--XXX
XX-XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX
XXXXXX---XXXXXXXX----XXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX----XXXXXXX----X----XXXXXXXXXXXXXXXXXX
-------XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX----XXXX-XXXXXXXXXXXX
-XXXXXXXXXXXX-----------XXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXX----------------------------XXXXXXXXXXXXXXXXXXX------X
X-XXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------
---------XXXXX---XXXXXXXXXXXXXXXX----------XXXXXXXXXXXXXX---
--XX----------------------XXXXXXXXXXX------XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXX---XXXXX-XX--XXXX--XXXXXXXXXXXXX-----------
-------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGGESTQAPSVFKQAK
DKVSDGITKSPEKRSALPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSSILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTALKMEFHDQQELTPSAAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TETSPFAPAFLQP-DDKKSLQQTSGPATAKDS----FKIEEPHEAKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LSKDAHIPVVEE--HVMGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKETELKLEE----KTTISDKEAVPKESKPP---KPAD--EEIGIIQTSTEHTFS-
-EQKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------T-TGEESTQAETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHVSGDKSGLSKESDQEKKANDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--EIETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEIAEVEPSKKVE-----QGLDFAV-------QDQLDVKISDFGQMASGLN
IDDRRA---TELKLEAT--QDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPGISITPSDVAEP
-LHETIVSEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---SEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVEEE-------------------------------------------------
--------------------------------EETLESRMAEEEKPAALPEKECGA----
AKSSDQPKGLSKGQMESSAEAQIVPEESAPAGAPHEKSVKEV-KEVSPEVKTPSSAGEDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPYEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEAPPSEEMT-LPKDTHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELELKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISDDKSGLSKEFDQEKKANDRLDTVIEKSEEHTDSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLMQPTSAGSTDRLPYSK
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSLSSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQDGAGEELVRSANGFPYREDEEGAFGEHGPEGTYSDTKENGINGELSSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
FTALKMEFRDQQELSPSTDEPLDQKAEESEKQIKPGEDLENAALVSQPETTKTSPDEKDL
QGE-EEEKALPSLF-----ASPEDLKQKTEPSLVVAGIGVPTEPPAQKEQKDWFIEMPME
AKKDEWGLVAPISPGPLTPMKEKDVLDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------LKNQIV-PTTSPFSPVLLQP--DKKSLEEASGPETAKDT----SKVEEPLKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAETPASAEIT-SHKDTDISIMEE--CITEKVSGEEKGAIEEESMQKKETSTPSGQ-E
PILTEKETQLKFEE----KITIPDKEAVPKESEPP---KLTD--DETSITQTTTEHTISK
EEQKGQEPTTDMLKQDLFPLSLEQEVTDSALTSKTLEKVLTEPCALSEKSSIQELFEEKV
ADKD-KVERVGAAASSELDMPFYEDKSGMSKYFETSALKEEVTKS--TQPGSDYYELSDT
RESAQ-ESFDTIAPTYK----NGEEETQAGKEPQPHAAAQETGYSTLAQSYPSE----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIENKEEEE
KIEE------------EK----------A-TGEENIHADTTCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVIEE-GTGL-PSVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSTEKETS-----PHMSGLGREFDQEKKVNDKLDTVLEKSEEQVDSKAHATT
TEEAGD-------------------KVETVE--LGVTDEQPLA-KEPAVSKDTPPPMAEK
AE-EGLSSVPEVVEVEPSKKAE-----PELDFAAEKADQ---GQLDVQISDFEQTPAELT
VDAGMV---TELELEET-QQDLAPSSKVPQEADAFMDVESVHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEIAIKLSVE
-------IPCAAAVSE-ADLATDERADVQMEFIQLPKEE----SKETPDISITPSDVTEP
-LLEGIVSEPAEA---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDEYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESAQAPGVFKQAK
DKVSDGVTRSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MADERKDDGKAPHWTSASLTEA-AAH
PHPPEMK--D---------------------QGG-----AGEGLSRSANGFP----YREE
E-EGAFGEHGSQGTYSDTKE-NGINGELTSADRETAEEV-SARIVQVVTAEAV-------
---------AVLKGEQEKETQHKDQPAALPLAAEETAHLPPSPPPSPGSEQTVAVEE---
------------------------------------------------------------
----------------------------------------------AAS-----------
----------------------------------------------GESAQAPSAFKQAK
DKATDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAP--AH
PHPPELKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQAAYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTALKMDFPGQQELTPSAAEPLAKQEEESKKQSKPGEDFQHAALVSQPETTKISPDTKDV
QGT-EEEKAPPALFGHTVGDSLEDTKQKTEPSLVVPDIGLHAVPSAPKEQKDWFIEMPTE
AKKDEWGLVAPVSPGPLTPMREKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEII-TETPPFAPALLQP-DDKKSLPETSGPAAAKDS----TKVEESHKDEP
K

PF08377 // ENSGT00530000063491_1_Domain_0 (602, 1964)

KEAEAPGSEAIT-LPKDDHVPAVEE--NVMVKVLGEEKGAIIQESVQKKEISTPSGQ-E
PTITEKEPQLMLEE----K-TLSDKDAVPKESEPP---KLGD--EETSIIQTSTEDTLSK
EEQKGQEPSTAMLKQDSFPVNLEQPVTDSVVTSKISEKVVSEPATLNEKSVTQELPEEKV
ADKD-KMEGVGAAKSAELDLPFYEDKSGMSKYFETSALKEEVTKS--IQLSSDYYELSDT
RESAR-ESIDAVSPTHK----NGDKELQAGKESQPSVPAQEAGYSTLAQTYQSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEEEK
PIQE------------EK----------A-AREENTQIETTSESSSLAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVM---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENVSGDSGAFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDELGAEKESSSPLISGDKSGLGREYDQERKANDKLDTVLEKGEEHVDSKEHAKE
TEEAD-----------------D--KVETIG--LAVSYEQAPA-KELTTSKEAPS---EK
AE-KVLSSVPEVAEVEPSKQAE-----QELDFPAKKGDQ---GQLDVQISDFGQMAAGLH
LDVGKA---AEVKLEAT--QDMTPSSKTPQEADAFMGAEPGHMKEGAKVNETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPEEGKKETSPESSLIQDEIAIKLSVE
-------IPCPPAVSE-GDLATDERAEVQMESIQLPKEE----SKETPDISITPSDVTEP
-VPEAVVSKPAEA---------PGEEEEIEARG---EYDKLLFRSDTLQIADLGVPGVKE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEM-ERR
PSPHDEE--------------------------ELEVEVAAEAQAEPRDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESTQAPSVFKQAK
DKVSDGVTRSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

MRRFYSLLSLSQETLIGNHSFRKLKGEFTRERRMADDRKDEAKAPHWTSSQLAEAS--SH
PHSPELKEQGGAGDGIVRSANGFPYREEEEGGYGDHGQQGTYSTTKENGINGELTTAERE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQPKDQPTGLPIAVEESANLPPSPPPSP--
ASEQTGTLE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------E--
--ASKMEFHEQQGTAPLTAEPLDKKEKEPGKESKPAELPKHDALVAQPAQPET-VDTKDI
HGK-EDGKAPLTLFEQTLGEEVEYMQQKSEPSSAALDVSFPVETVFQKEQKDLSIEV---
-PKDEWSTYSQLSPGPLTPMKENYDIQGIPKWDGKKLDSPKPTPFGSVS---FPLPSEPK
IDLSDATKDKFV-SEALSLAPETLKP-EDKKAKEEPSGPQITKEI----PKEEQKHVEKT
SKAEE-TASMEIT-PSI

PF08377 // ENSGT00530000063491_1_Domain_0 (618, 1964)

ETDKAT-VESPVQKISSVGQEKDVIKQESEQKKEPSTFDGQ-K
STLFDSEFHPKPEE----KNIIPEKKITSKEGETQ---KILD--EEMGIISVSTEKTFQK
EEKKDQKTPVD----DSFPESLEQTLSVAATTSKMLDKASDELRLLSEKSAMKEIFQEEI
VDKDLEAHGTGVAASLDFDRHLDEDKSGMSKYFETSTLKEETTKS--IQSGSDYYELSDT
KE-SY-ESYDTISPIHK----GSEKEFYPGKEQQS-TPMLEGGYSTLAQSYPAD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIESKEEEE
QLEE------------EK----------V-TRAENIQVESLCESPFLAKDYYKNGSVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PAVT---DENHVSPKA
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGPFYDSSDDKIRRDLAADLSLIEVKLA
AAGRVKEDFSSEGELS-QAISSDKSVLGREFDHERKSNDKLDTVLEKSEEHIESKEILLL
EEKEQPIKVPEGV---------D--KVEAFG--TGMTFEQVFG-KEPIKPKDASIFISEK
AE-KSLSSVPEVAEAEPSPKAD-----HALDDGAKKVEQ---SEPDAKISDFGQAASGLR
VDTEKG---TEPCTQAA--QEDKTHLAKPPEAAAFPSTEPSHLKESIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHDHTPESLTMESLKPDEGKKEVTPEVTVLQEDITIKLPTE
-------EPPAISDSK-SYEEQPEGTEIQMEPDQQPKEE----VKETPDISITPSEVIEP
-LLQGIVSEPDKVPKVEEEEEVEEEEEEIEARG---EYDKLLFRSETLQITDLSVPAVKE
-ELVELSAAEMPEYKGVIESVVTIEDDFITVVQTTTDEGETGSHSVRFAALEQSEV-ERR
SSPPEEE---------------------------PQVEESAEALEEPKEGSPEAPASPEK
E-EVGFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETVPKEEKAEKEVR-R------------------PSLDKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LGKKTEVQAHSPSRKII---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GETNQASGTFKQGK
DRFSDGVSKSPEKRSSLPRPSSILPTRRGVSGDR--DENSFSLNTSMSSSVRRTTRSEPI
R-RTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVRSKIGSTDNIRYQPKGGQVRILNKKMDF
SEVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

IQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HIPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPYEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELELKLEE----KTTIFDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDEEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDTRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVIEKSEEHADSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTEASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
----EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAGLPIAVEESANLPPSPPPSP--
ASEQTGTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHEQQGTGPLTGEPLDKKEKESEKGSKPAELPKHDALVAQPAPP---IDKKDI
HHR-EDEKVPLTPFAQTFGEELEYMQQKSEPIAAALDVDFPTETVLQKEQKDLSIEV---
-PKDEWSTYSQLSPEPLTPMKENYEVQEIPKWDGKKLDSPRPTPFGSMS---FSLPSEH-
-----ATKDKLE-SKALPSTTEALKP-EDKKPE-EVSSSQIAKEI----PKDEQIHMEKT
LKAEETTASMEIS-SS

PF08377 // ENSGT00530000063491_1_Domain_0 (617, 1964)

VKAEKPTVSESPIKKISSVGEEKDVIKQESEQKKEPCTFNGQ-K
STLFDSELYPKPEE----KNVIPEKKTLLKESEPQ---K-ID--EEMDISSVSTEKTFQK
EEKKDQKIPTDDLSRDSFSEGIEQVLSGAATTSKMLDKTPDELGLLSEKSASKELFREEI
VDKDMEVHRTGAASSLDYNRQLDEDKSGMSKYFETSTLKEETTKN--IQSGSDYYELSDT
KESVY-ESYDTVSPIHK----SSEKEFYPEKEQQP-APVLEGGYSTLAQSYPAD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIESKEE-E
QLEE------------EK----------V-TRADNIQVESLCESPFLAKDYYKNGSVMAP
DLPEMLDLAGTRSRLASMSADAEVARRKSVPSETLLEESSTGL-ATPT---DENHVATKA
DSQLEDLGYCVFNKYTVPLPSPVQDSDNLSGESGSFYDGSDDKIRRDLATDLSLIEVKLA
AAGRVKEEFSSEGELA-QPISEDRSGLGKELDHERKSNDKLDTVLEKSEEHIESKEILLL
VEKEYPKK-AEGV---------D--KVEAFG--TGMTFEQVFG-KEPIKPKETSIFTSEQ
AE-KSLSSVPEVTEAESSPKAD-----HGLDADAKKVEQ---SQPEAKISDFGQAALGMV
GDTEKG---TEPHIQAV--QPDRTHTAKPPEGDTFPSTEPSHLKESSKVSETEVKEKVPK
PDLVHQEAVDKEESYESSGEHDHTPESLTMESLKADESKKEVAPEVTVLQEDIPVKLPAE
-------EPPAVSDLK-SYVVQTEGPDIQMEQVQQPKED----VKETPDISITPSEVIEP
-LLQGIVSEPEETQ--------REEEEEIEARG---EYDKLLFRSETLQITDLSVPAVKE
-ELVELGAAEMPEYKGVIESVVTIEDDFITVVQTTTDEGETGSHSVRFAA--LEQP-ESR
ASPPEEE--Q---------------------EEEVQIEKSAEAVGEPKEGSPEAPASPEK
E-EIGFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRS--IMT-EQL-------
---------ETVPKEEKAEKE-VRR------------------PSLDKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LGKKTEVQAHSPSRKII---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GETNQASGVYKQAK
DKFTDGVSKSPEKRSSLPRPSSILPTRRGVSGDR--DENSFSLNTSMSASVRRTTRSEPI
R-RTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSGILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVRSKIGSTDNIRYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKMDF
SEVQSRCGSKDNIKHSAGGGNIQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HIPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADEQKDEAKAPHWTSAQLTEAS--AH
PQPPEIKDQAGAGEGLVRSANGFPYREDEEGAYGEHGPQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTIPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPDHQELTSSAAEPLDKKEKESKMESMPGEDFKHAALVPQPDTTQTFPDTKNM
QGA-EGEKAPPALFGHPVGATLEDMKWKTEPSFIVPGIDLPAQPPSPREQKDWFIEMPVE
TKKDEWGLAAPMSPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFQPGS---FTLPVDV-
------MKNEIV-TEASPFEPGFLQP-DNKKSLQEISGPVTAKDS----SKVEELQKDEP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAETAASEAIT-LPKDPHVPVLEG--YVIEKVLGEKRGT-------------PSGQ-E
PTLTEKELQPKLEE----KTCVSDKEAVPKEHEPS---KLRD--EETAIIQTATEHTFLK
ETPKSQEQITDMLEPGTFPVGLEQAVTDSTMTLNTLEKVSTEPAALYEKSTLQELFQEKV
ADTDSNVEGVRDAPSAEIGMPFYEDKSGMSKYFETSALKEEVMKN--IQLASDYYELSDT
RESAH-ESADTISAMLE----SDDKEFQVGKESQPSAPAQGAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKAPCFPIESKEEEE
KTEE------------EK----------A-TGQENIQVETSCESPFVAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVT---DENHTIVKT
DSHLEDLGYCVFNKYTVPLPSPVQDSENLSGESGCFYEGSDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKETS-----SPTSGLVREFDQERKANDKLDTVLEKSEEHADSKEYAME
TEEAG-----------------G--KVDTFG--LGLMYKPTSA-KELTVSKDAAF---EK
AE-KGLSSVPEVAEVEPSKKTE-----QGLDFAATKADQ---GQLDVKISDFGQITARLN
VDAGEA---AELKLKGA--QELALSSKAPQEADVFLGVEASHMKEGARVSEIEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEAKKEMSLESSLMQDEIAIKLSVE
-------IPGPPAVSE-ADLAAAEQADVQMEFIQMPKEE----SKEAPDISITPSDVTEP
-QLEAVISEPPEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-QRR
PSPHEEE----------------------------ELEVAAEAQAEPKDGSPEAPASPER
E-A-VLLEYK-TETYDDYKDETTIDDSVMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATG-----------
----------------------------------------------GESTQAPSAFKQAK
DKVSDGITKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSISSSVRRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKTDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVEEE-------------------------------------------------
--------------------------------EETLESRMAEEEKPAALPEKECGA----
AKSSDQPKGLSKGQMESSAEAQIVPEESAPAGAPHEKSVKEV-KEVSPEVKTPSSAGEDL
LTASKMEFHDQQELTPSAAEPLDMKEAESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPME
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPYEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEAPSSEAMT-LRKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFIPSGQ-E
PILTEKELELKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDLFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------IK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLGKEFDQEKKANDRLDTVIEKSEEHADSKEHAKK
TE--------EAG---------D--EVETFG--LGLTYEQALA-KDLSMPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAGGESTLAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLMQPTSAGSTDRLPYSK
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWSSAQLTEAP--TH
PHPPEIKDQAGAGEGLVRSANGFPYREDED------GPQGPYSDTKENGINGELSSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPTALPLAAEETANLPPSPPPSP--
ASEQTIPLE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDKKEKESKMESMPGEDLKHAALVPQPDTTQTSPERKDT
QGA-EGEKAPPALFGHPVGATLDDTKQKAEPSFVVPGIGLPAQPPAPKEQKDWFIEMPVE
TKKDEWGLAAPVSPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFQAGS---FTLPVDI-
------MKNEIV-TEASPFDTGFLQP-DNKSSLQEISGLVTAKDS----FKVEVSQKDTP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKAAETTTSEAIT-LPKDAHVPIVEG--YVIEKDLGEEAGVIHQE---KKEISIPSGQ-G
PILTEKELQPKPEE----KTSISDKEAAPKEHEPS---KLRD--EETGIIQTATEHIFLK
EESKGQEHPTDILKHGSFPASLEPSTTDSTMTLNTLEKVSPEPAVLHEKSTLQELFQEKV
TDKDSKVEEVGAASAAEVDMPFYEDKSGMSKYFETSALKEEVTKS--PQLASDYYELSDT
RESAR-ESVDTTSAMHE----NGDKGFQAEKESQPCAPAQEAGYSTLAQSYPSD----VP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPRFPIESKEEEE
KVEE------------EK----------V-PGEENTQVEAPCESPFVTKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEAARRKSVPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGSDNKVRRDLATDLSLIEVKLA
AAGRVKDELSAEKET------SPTSGLLREFDQERKANDKLDTVLEKSEEHADSKEHAKE
TE--------EAD---------V--KVDTSG--LGVTQKPTSA-KELTVS---KDAVPEK
AE-KGLSSVPEVAEVEPSKKSE-----QEQDFAATKADQ---GQLDVQISDFEQTMARLN
EDAGKA---AELKVEAA--QELAPSSETPQEADVFLSVEAGHVKEGARVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKELSPESSLIQDEIAIKLSVE
-------IPCPPAISE-ADLATDERADVQMEFIQMPKEE----SKETPDISVTPSDVTEP
-QLEAVISEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVAGVRE
-ESVETCP---GERKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHEEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E--AALSEYK-TDTYEEYKDETTIDDSVMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATG-----------
----------------------------------------------CESTQAPSVFKQAK
DKVSDGITKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSFPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKTDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
PHPPEMKDQGGAGEGLVRSANGFPYREDEEGTFGEHGSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAPLPLAAEETAHLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPDQQALTPSTAEPSDQKEKESKTQSKPGEDLKHAALVPQPETTKISSEIKDM
QRT-EGDEVPPALFGHPLGDSLEDIKQKTEPSLVVPGIGLSSEPPAPKEQKDWFIEMPME
TKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFQAGS---FTLPVDV-
------MKNEIV-TEATPFAPVLLQP-DDKKSLQETSGPATAKDS----SDVEEPQKVKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAETPASEAIPSSPRDAHFPVVEE--SVIEKIFREEGEVIKQE---KKETFTPFGQ-E
PTLFEKEPQPKHED----KTIVSDKEAAPKEIEPL---KSRD--EETGVTQTSTEYTFSK
EEQKDQEHTISVLKDDSFPA-----VTDSTMTSKTLEKVMPEPAALSEKSAAQELFEEKV
ADKDHKIEGAEAATSAEVGMPFYEDKSGMSKYFETSALKEEATKS--IQLGSDYYELSDT
RESAR-ESIDTVSPKHQ----NGDKGFQAEKESQPSAPAQEAGYSTLAQSYPSE----VS
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAMDKAPSFPIESKDEEE
KVQD------------VK----------T-TGEETTQVETTCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PSVT---DENHVVVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKEAS-PPTSGDKAGLGREFDQERKANDKLDTVLEKGEEHAKETEE---
-----------AG---------G--KVETFG--LGLTHEQASA-QELPISKEVSS---EK
E-EKGLSTVPEVAEVESSKKAE-----QGPDFTAKKADQ---GQFDIKVSDFGQMASGLN
VDDGKT---TELQLEAA--QELVPSSKVPQEADAFLGIEAGHAKEVAKVNETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEVAIKLSVE
-------IPCPPAVSE-ADLAADEKAEVQMEFIQLPKED----SKETPDISVTPSDVAEP
LLEAAVVSEPAEA-----------EEEEIEARG---EYDKLLFRSDTLQITDLGIPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQHEV-ERR
PSPRDEE--------------------------ELEIEVAAEAQAEPKDGSPEAPASPER
E-EIGLSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--QLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAASGESAQAPSVFK
QAKDKVSNSTLSKIPASQGSTKSPRYSSACPSMTKRATFSDSFLIQPTSAGSTDCLPHSE
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHESQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVAVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFPDQQELTPSPAEPLDKKEKESEKESKPGEDLKHAALVSQPETTETSPEKKDM
QGT-GEEQAPPTLFGHSFEASLEDMKQKTEPSLGVPDIGLPAEPPAAKEQKDWFIQMPVE
AKKDEWGLVAPVSPCPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPLGV-
------VKDEVI-AEASPFAPALLQL-DDKRSLEETGILGTTKDS----SKVEELQKDQP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMTETPASEAIT-SPKDAHISIVEE--CVPERVL-EEKGAIKQESMQIKETPTLIGQ-E
PTLTEKEPHLKLEE----KPTVSDKEATPKESEPP---KLTD--EEIGVIQPSTEHTYSK
VDQKGQEPTTDIPKQDSFPVSLEQAVTDSTMTYKTLETVMTEPAVLSEKSAAQEPFEEKV
ADKDSKVEAVGAVTSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
RESAQ-ESFDTVSPTYK----NGDKGLPADRESQPSVLAQEAGYSTLAQSYPSE----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX-X
XXXX------------XX----------X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKDTS-PHIPGDKSGLGREPDQERKANDKLDTVLEKSEEHADSKEHDKE
MEEAGD-------------------KVETFG--LGVTLQELSA-KELTVSKDASPLVAEK
VE-KVLSSVPEAAEVEPSKKAE-----PELDFAAKKADQ---GQLDVKISDFGQMASGLN
VDAGKA---TELKLEAT--QDLTPSSAAPQEADAFMGVESGHVKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPAVSE-ADLASDEKADVQMEFIQPPKEE----SKETPDISVTPSDAAEP
-LPEAARAEPAEA---------PSEEEEIEAQG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPRAEE--------------------------ELEVEEAAEAQAEPKEGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESAQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2306)

VKIESVKL
DFKEKAQAKVGSLDNAH-V-PGG-NVR---------------------------------
---------------------------------------

---------------------------------MADDRKEEAKMPHWTSAQLPEAT--GH
PHPPEMKDQAGAGEGLVRSANGFPYREEEEASFGEHGSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKEQPAARPLAAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHEQKALTSSTVESLDKKEQESKIQSKPSEDIEHAALVPQLETTHTSLEQKDL
QDT-EGEKAPLPLIGHPLGASLEGTKQNTEPSLVIPGIGLSAEPPALKERNDWFIEMPVE
SKKDEWGLAAPISPGPLTPMREKDVFEDIPRWEGKQFDSPMPSPFQGGS---FTLPLDI-
------MKNEKI-TETLPFAPVIFQP-DDKKPLQDISIITTAKDS----SKAEEPPEDKP
H

PF08377 // ENSGT00530000063491_1_Domain_0 (602, 1964)

KVEPTPASGAIA-LPKDAPGPAVEG--YVLEKVLVEEKQSINQE---KKEDSVPSRQ-E
PILSEKEPQPKLEE----KTPTADKGAVREEKEPP---QLRN--EETGPIQAT-EQSFSR
-EQKGPENTTDVIKQDSFPASLEQAVVDSAMTSKTLEKDTVEPAGVSEMKETQGLFEEKV
SDKEK-VEGVG----AEGGMPFYEDKSGMSKYFETSALKDEVTKG--SQLGSDYYELSDT
RKSTLDEPLDTTCPKYQ----DDGKGLQAETESQPSAPAQEAGYSTLAQSYPSK----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVDKAPCFPIESKEEEE
KIEE------------EN----------A-ARGQNTQVEASCESPFLAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSTDAEVARRKSVPSETVFAESSARL-APGP---DENHVMTKS
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGADDKVRRDLATDLSLIEVKLA
AAGRVKDESSAGKKSP-VPTAAEKPGLGRELDLDRKANDKLDTVPEKSEEHVDLKEHATD
IE---------DG---------D--KVETFG--LGVTSEQDAT-KELTVAKGAS---PEK
VEKGLLSSVPEVAEIEPSKKAE-----QGLDFAAKKADP---GHLDVKVSDFGQMASGMN
VDVGKA---TELKLEAT--QELTPSAEAPQEADAYR-------KESAKASETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPEEGKKETSPESSLIQDEVAIRLSVE
-------IPCPPAVPAAADVAADARAEVQTEFIQPPARE---ESQESPEAPASPPDAAQL
QPEEAVVSEPAEA---------PSEEEEIEARG---EYDRLLFRSDTLQIADLGAPGSGA
AAFVEACP--PGERKGGIESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEQQERR
PSPHEEE--L------------------------PGDEAAAEAQAGPKEGSPDAPASPDR
E-EVAFSEYK-TEPYDEYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEDKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--QLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------GDPAQGRSAFKQAK
DKVTDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSVRRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQSTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAEHKVQPAALPLAAEETPNLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LPASKMEFHDQQELTPSPAEPLDKKEKESEEQSKPGEDLKHAALASQPETTKTSPDKKDT
QGT-EEEKAPTALFGHALGAGLEDMKQKTEPSLVVPGIDLSAEPPAPKEQKDWFIEMPVE
AKKDEWGLAAPISPGPLTPMKGKDVFEDIPKWEGKQFDSPMPSPFQAGS---FTLPLDV-
------IKNEIV-AEASPFAPALLQP-DDKKSLEETSGPVTAKDS----SKAEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPASEAIT-LPKDAHIPTVEE--YVPEKVLGEEKGAIKQESVQKTEISTLSGQ-E
ATLTEKESQLKLEE----KTTISDKEAMPKESEPP---KLTD--EETGIIQPSVEHTLSK
EEQKGQDTTRDTLKQDSFPVSLEQTVTDSAMTSKTLEKVMTEPAAVSEQSATQDLFQEKV
ADKDHKVEGVGAETSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
RESAQ-EPFDTVSPAYK----NGDKGLQAGKEPQPSAPAQEAGYSTLAQSYPSE----VP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEEEE
QIEG------------EK----------A-TGEENAQVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSAGL-PPVT---DENHVVVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKMRRDLATDLSLIEVKLA
AAGRVKDEFGAEKEVS-PHIPGDKSVLGREFDQERKANDKLDTVLEKSEEHADAKEHAKA
TE--------EAS---------D--KVETFG--LGVTYEHPST-KELPVSKDTSPPAAEK
AE-TGLSSVPEIAEVEPSKKAE-----PELDVIAQKADQ---GQLDVKISDFGQMAAGLT
IDAGKA---TELQLEAT--QDLTPSSAVPQEGDMFLSVDPGHMKEGTKTSETEIKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPAVSE-ADLAPDERADVQMEFIQQPKEE----SKEAPYISVTPSDVTEP
-LPKAIGAEPAEV---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGIAGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTEEGESGSHSVRFAALEQPEV-ERR
PSPHAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATGGETTQASSVFK
QAKDKVSNSTLSKIPAFQGSSKSPRCSSACLSTSKRATFSDSFSIKPTSAGSTDRLPFSE
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPSDKKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPME
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TETLPFIPAFLQP-DDKKSLQQTSGPATAKDS----FKIEEPHEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LSKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDSFTPSGQ-E
PILSEKEPELRLEE----KTTISDKEAVPKESKPR---KPTD--EETGIIQTSTEHTFS-
-EQKDQEPTTDMLKQDSFPVSLEQAVTDSAVTSKTLEKAMTEPSVLIEKSSIQELFEMRV
DDKD-KIEGVGAATSADFDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGNVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--EAETFG--LGVTYEQALT-KDLSIPTDASS---EK
AE-KGLSSVPEITEVEPSKRVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRA---TELKLEAT--QDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----IKETPDISITPSDVAEP
-LHEAIVSEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPRDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSVSSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADNRKDEAKAPHWTSSQLTEAS--SH
PHSPEIKEQAGAGAXXXXXXAGY-------------GQQGTYSRTKENGINGELSTGDRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPLAVEEAANLPPSPPPSP--
ASEQMGTLE---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-DASKMEIRDQEGKGPFTAEPLDTKEHKSEKDSKTGEQPKHDALVPQPAKTETLA-KKDS
WGK-EEEKISPTVSGQILDADLQK---KGEVSL--------AEPLISQGHRDLSVDLLKE
SRTDGRSTDTQIPSSQAIPLKYKDDFTDTQKSHL------------------ASLPSEFR
MDVSGADPRETPSE-IPVSVPQKLQLEDSCKTSHEPTDTEAAKEL----SKDEKIHKDNT
EKPAGE

PF08377 // ENSGT00530000063491_1_Domain_0 (607, 1964)

EV---AA-MAAHAPKPTTGETLTQKVSTWGEEKDMTRDESDEEERYGFLDWQPS
KAVDDSQLYTEQED----KRIVPDKAIVSETKKPS---DVLRTEEETDRTGVSAVLDVKK
EEQQSTETPTGELSHDSFSEEAKISIDTA--QLSKTEKTPDAPRLTSEKGPTHELSQDRD
IEKKSEEETFHISDTATREIQVEEDRSGMSTYFETSALKEEAIKSDMQPPGSDYYELSDT
KESMY-ERYPADPLISK----MEDKKFPPETDQPSSVPGHEIGYSTLAQSFPSD----KP
EEPSSPQERMFTIDPKVYGDKREIHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFSFGRAQDLSPLASDILTNTSGSMDEGDD-YLPATTPAFERAPCFPIESKEEEE
IIEE------------EK----------A-MEEENMPVESLCESPFLAKDYYKNGAVMAP
DLPEMLDLAGTRSRLDSVSTDAEVAQRKSLPSDADAEDSGAPL-TPLT---DENHITLKA
ESQLEDLGYCVFNKYTVPLPSPVQDSESLTGETCPFYEGKDEKMRRGLVADLSLIEVKLA
AAEKSKE--FSERDLS-PNISSDPTVLGREFELEKRGSDKLDTVLEKCEEQVDSKEAYSL
EDTKHEKKMPDAILERKEDGAID--KLYVAGPEVDTTHDKALA-KEASKEKDVVSLLTEK
EE-KPLSIAPKEAKIESPHKPDYDAIKHDMDVAARQAEQEYQTRTHTEISEFAEAGLKQD
TDSVKT---AEPDTQEP------QQPKEPKEADVPSRTEPSQMKDSTKVSDTEIKEKVTK
PDLVHQEAVDKEESYESSGEHDQIQEELNGESLKPDDSKIEPQK-PPVSEEETTSQLPVG
-------EPSIPLAVSKPDSVQEEAADIQMESIPHPEEE---VKETAPDMAVGPAETTEQ
PVHDVI-HESVQVKEHEEE-------KEKEEEK---EDEKHQLMSEPPQEIELE---AAE
EVLTESGPEEMPELKGVIESVVTIEDDFITVVQTTVDEGELASHSVRFAAPQQGELERGD
FLPEEE--------------------------VEMEVEEPSDGQAEPKEGSPEAPASPEK
E-EILLTDYK-TETYDDYKDETTIDDSIMDTDSLWADTQDDDRSIM---TEQL-------
---------ETVPKEEKAEKELRR-------------------SSLDKHKKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAE
LAKKSEVQTHSPSRKII---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KQTAAG-----------
----------------------------------------------GETNQAPGVFKQAK
EKLSDGVTKSPEKRSSLPRPSSIIPTRRGVSGDRDRDENSFSLNSSISSSLRRTTRSEPI
RSRTGRSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVRSKIGSTDNIRYQPKGGQVRILNKKIDF
SDIQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HTPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
PSPRRLSNVSSSGSINLLESPQLATLAEDVTAAFAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVEEE-------------------------------------------------
--------------------------------EETLESRMAEEEKPAALPEKEYGA----
AKSSEQPTGLSKGQVESSAEAQIDPEESAPAGAPHEKSVKEV-KEVSPEVKTPSSAGEDL
LTASKMEFHDQQELTPSAAEPLDKKEKESEKQSKPGEDLKHAALVSQPETTKTYPDEKDM
QGT-EEEKAPLALFGHTLVANLEDMKQKTEPSLVVPGIDLPKEPSTPKEQKDWFIEMPTE
AKKDEWGLVAPVSPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKSEIV-TETSPFAPAFLQP-DDKKSLQQTSGLATAKDS----SEVEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEVPSSEAMT-LPKDAHIPVAEE--HVMGKVLEEEMEAIKQETVQQKDTFTPSGQ-E
PTLTEKEPELKLEE----IATISDKEAVPKDTRPP---KLAD--EETGIIQTSTEYTFS-
-EQKSYEPTTDMLKQDSFPLSLEQAVTDSAVTSKTLEKAMTEPSALIEKSSIQELFDMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IQPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVENKEE-E
QMEK------------VK----------T-TGEENTQAETTCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-PPISVDKSGLSKEFDQERKASDRLDTVLEKSEEHADLKEYAKK
TE--------EAG---------D--K-ETFG--LGVTYEQALA-KDLSILTDASS---EK
AE-KGLSSVPEVAEVEPSKKAE-----QGLDFAANKVVQ---GQIDVKISDFAQMASGLN
IDARRA---TELKLEAS--QDMTPSSKALQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCPPTVPE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-VHEAIVSEPAEV---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGASGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALDQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESAVAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLIQSTSAGSTDRLPYSK
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEGKAPHWTSASLTEAA--AH
PHSPEMKDQGGAGEGLSRNANGFPYREEEEGAFGEHRSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTATVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPEQEKFPSSFAEPLDKGEMEFKMPSKPGEDFEHAALVP--DTSKTPQDKKDL
QGM-EGEKLPPVPFAQTFGTNLEDRKQSTEPSIVMPSIGLSAEPPAPKEPKDWFIEMPTE
SKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FTLPLDT-
------MKNERVSEGPRPFAPVFFQS-DDKVSLQDPSALATSKES----SKDEEPLKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVADVSISEVTT-LLGNVHSPVVEG--YVGENISGEVKVTTDQE---KKETSAPSVQ-E
PTLTETEPQTKLDE----KSTVSIEEAVAKKEESF---KLRD--DKTGVIQTSTEQSFSK
EDQKGQEHTIDELKQDSFPISLEQAVTDAAMTSKTLGKVTSEPEAVSERREIQGLFEEKT
ADKN-KLEGAGSATIAEVEMPFYEDKSGMSKYFETSALKEDMTRS--TELGSDYYELSDS
RGSAQ-ESLDTISPKNQ----HDEKELQ-AKASQPSPPAQEAGYSTLAQSYTPDHPSELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKMPCFPIESKEEED
KAEQ------------AK----------V-TGGQTIQVETSSESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSEAMLAESSTSL-PPVA---DESPVTVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFTAEKEAS-PPTSADKSRLSREFDHDRKANDKLDTVLEKSEEHIDSKEHAKE
SEEMGG-------------------KVELFG--LGITYDQAST-KELITTKDTSP---EK
T-EKGLSSVPEVAEVEPTTKAD-----QGLDFAATKAEP---SQLDIKVSDFGQMASGMN
VDAGKA---IELKFEVA--QELTLSSEAPQEADSFMGVESGHIKEGGKVNETEVKEKVTK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPETSLIQDEVALKLSVE
-------IPCPPPVSE-ADLSTDEKGEVQMEFIQLPKEE----STETPDIPAIPSDVTQP
-QPEAIVSEPAEV---------PSEEEEIEAGG---EYDKLLFRSDTLQISDLLVSESRE
-EFVETCP---GELKGVVESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEE-ERR
PRPHDEE---------------------------LEIEMAAEAQAEPKDGSPDAPATPEK
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIL---TEQL-------
---------ETIPKEERAEKDARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKSEVQAHSPSRKLI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAS-----------
----------------------------------------------GDLAQAPGAFKQAK
DKVTDGISKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRT---PGTPKSGILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQAGAGDGLVRSANGFPYREDEEGAYGEHGPQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTTEAVAVLKGEQEKEAQHKEQPAALPLAAEETANLPPSPPPSP--
ASEQTIPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDHQELTPSAAEPVDKKEKESKMESKPGEDLKHAALVPQPDTAQTSPDTKDM
QGT-EREETPPALFGHPVGATLEDMKWKGEPSFVVPGIGLPAQPPTPKEQKDWFIEMPVE
TKKDEWGLAAPVSPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFQVGS---FTLPVDV-
------MKNEIL-TEASPFESGLLQP-DNKKSLQEISGPLTAKDS----SKVEEPQKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAETAASEAIT-LSKDPHFPVMEG--YVIEKVLGEDRGT-------------HSGQ-E
PTLTEKELQPTLEE----KTSISDKEAVPKEHEPS---KLRD--EETGITQTSTEHTFLK
EAPKGQEHITDMLKQDSFPADLEQAVTDSTMTLNTLEKVSTEPAALYEKSTLQELFQEKV
ADKDSKAEGVSAAPSAEISMPFYEDKSGMSKYFETSALKEEITRN--IQLASDYYELLDT
RESAH-ESANTVSVMHE----NDDKELQAGKESQPSKPEQGAGYSTLTQGYPSN----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAMEKAPCFPKESKEEEE
KTEE------------EK----------A-AGQENTQIETSCESPFVAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADVEVARRKSVPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGSDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKELS-----SPTSGLVREFDQERKANDKLDTVLEKSEEHADSKEYAME
TDEDG-----------------G--NMDTFG--LGVSLKPSSA-KAPTVSKDAAS---EK
AE-KGLSSVPEVAEVEPSQKTE-----QGLDFAAAKEDE---GQLDVEISDFGQITARLN
VDSGKA---AELKLQSV--QELALSSEAPQEADMFLGVEAGHVKEGARVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMDSLKPDEGKKEMSPESSLIQDEIAIKLSVE
-------IPCPPAVSE-ADLAAAERADVQMEFIQMPKEE----SKEAPDLSITPSDVAEP
-QLEAVVSEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLAVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHEEE----------------------------ELEVAAEAQAEPRDDSPEAPASPER
E-A-ALSEYK-TETYDDYKDETTIDDSVMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------SEPTQAPSVFKQAK
DKVSDGITKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFPLNSSISSSVRRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPSEQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TETSPFAPAFLQP-DDKKSLQQISGPATAKDS----FKIEEPHEAKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LPKDAHIPVVEE--YVTGKVLEEEKEAINQETVRQKDTFTPSGQ-E
PILTEKETEPKLEE----KTTISDKEAVPKESKPP---KPAD--EETGIIQTSTEHTFS-
-EQKDQEPTTDMLKQDSFPVSLEQAVTDSALTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVQ-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKERAKK
TE--------EAG---------D--EIETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEIAEVEPSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRA---TELKLEAT--QDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHETIVSEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---SEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHEEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

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----------------------------------MADERKEEAKASHWTAAPLTEA-AAH
PHPPEMK--D---------------------QGG-----AGEGLVRSANGFP----FREE
E-EGAFGEHGSQGTYSDTKE-NGINGELTSADRETAEEV-SARIVQVVTAEAV-------
---------AVLKGEQEKEAQHKDQPTALPLAAEETAHLPPSPPPSPASEQIVTVEE---
------------------------------------------------------------
----------------------------------------------AAG-----------
----------------------------------------------SESTQDPSAFKQAK
DKVTDGISKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKPPHWTSTQLTEAS--AH
PHQPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHESQDTYSNTKENGINGELTSADRE
TA----------------------------------------AAEDTANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
FTASKMEFQDQQELTPSTAEPLDKKEKESEKQSKPGEDLKHAAFVSQPETTKTYPAQKDM
QGT-EEEKASPALFGHSLIASLEDVTQKTEPSLVVPGIDLPAEPPAPKEQKDWFIEMPME
TKKDEWGLVAPISPGPLTPMREKDVFEDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKSEVV-PETSPFASAFLQP-DDKKSVQETSGPATAKDS----SKVEEPHKDKT

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DRMAEVPASEAIT-LPKDAHIPVVEE--NVMEKILEGEIGVVNQESVQKKDTFTLSGP-E
PTLTEKEPQLKLEE----KTTISDKEAVPKESTPL---KLAD--EETGIIQISTEHTFSK
-EQEGQESTADMLKQDSFPVSLEQAITDSTMTSKTLGKVMTEPAALTEKSVTQEIFEEKV
TDKANRVEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
REIAP-ESIDTVSPVHK----NGDKGFQA-EDSQPSAPAQEAGYSTLAQSYPPE----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKGPCFPVESKEE-K
QTEK------------EK----------A-TGEEITQVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVSRRKSVPSETVVEESSTGL-PPVT---DENHIVVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKARRDLATDLSLIEVKLA
AAGRVKDEFSVEKEAS-PHISDDKSGLGREFDQERKVNDKLDSVPEKSEELADSKEHGKE
TEEAV-----------------D--KVETFD--LGITYEQAPA-KELTISKDASS---EK
AE-KVLSSVPEVAEVEPSKKAD-----QELDFAAQTAAQ---GQLDVKISDFGQMASGLN
IDAEKA---TEFKLDAT--QDLSPSSKVPQEADAFMSVESGHMKEGAKVNETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEIAIKLSVE
-------IPCPPAVSE-ADLVTDERADVQMEFIQLPKDE----SKETPDISITPSDVTEP
-LLGAVVSELAEA---------QREEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPDV-ERR
PSPRDEE--------------------------ELEIEEAAEAQAGPKDGSPEAPASPER
E-EIALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------GESPLAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MAEERKDEAKAPHWTSAPLTEAS--AH
PHPPEIKDQAGAGEGLVRSANGFPYRDDEEAAYGEHGPQGPYSDTKENGINGELTSGDRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEVQHKDQPTALPLAPEETANLPPSPPPSP--
ASEQTIPLE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPDQQELTSSAAEPLDKKEKESKMESKPGEDLKHAALVPQPDTTQTPPERKDT
QGA-EGEKAPPALFGHPVGATFEDMKQKAEPSFVVPGIGLPAQPPVPKEQKDWFIEMPVE
TKKDEWGLAAPVSPGPLTPMREKDVLEDVPRWEGRQFDSPMPSPFQVGS---FTLPVDI-
------MKNEVV-TEASPFDPGFFPP-DNKNSLQEVSGPVAAKDS----SKVEDSQKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAETAVSEAIT-LPKDAQVPVIEG--YTIEKDLGEDTRVIHQE---RKEISTPSGQ-E
PTLTEKEFEPKLEE----KTSISDKVAIPKEHEPS---KLRD--EETGIIQTATEHSFLK
EEPEGQEPTADLLKQGSFPSSLGQSMTDSTMTLNTLEKVSVEPAALYEKSTLQELFQEKV
TDKDSKVEEVGATSAAEVGMPFYEDKSGMSKYFETSALKEEVTKS--IQLASDYYELSDT
RESAR-ESVDTISAMHE----DDDKRSQAEKESQPCAPAQEAGYSTLAQSYPPD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPCFPVESKEEEE
KAEE------------EK----------A-TGGEMAQVETSSEPPFVAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVIEESHTGL-PSAT---DENHVMVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSEESGSFYEGSDSKVRRDLATDLSLIEVKLA
AAGRVKEEFSAEKET------APTSGLLREFDQERKANDKLDTVLEKSEEHGDSKEHAKE
AE--------EAG---------A--KVDAFG--LGVTHKATPA-KEPTVAKDAAA---EK
AD-KGLSSVPEVAEIEPSKKLE-----EGLDL---------AGQLDVRISDFGQITAKLS
ADAGKA---AELEVEAA--QELAPSSKALQEADAFLSAEASHGKEGARVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPEEGKKEMSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADSAADERADVQMEFIQIPKEE----SKETPDISVTLSDVTEP
-QLEAVISEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVAGLRE
-ESVETCA---GERKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHEEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E--AALSEYK-TETYEEYKDETTIDDSVMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAGKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSREEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATGGESTQAPSVFK
---------------------------------------------------------QAK
DKVSDGITKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISASARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSFPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTETYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPYEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELELKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KTEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDTRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVIEKSEEHADSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

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----------------------------------MADER---------------------
------------------------------------------------------------
------------------KDE--------AKAPHWASAQLTEASAH---PHQPEIKDQGG
AGEGFVRSANGFPYRED-----ED-------------------GAFGEHGSQGTYSNTKE
NGIN----------------------GELTSADRETAEEVSARIVQVVTAEAVAVLK-GE
QEKEAQ-HKDQPAPLPLAAEETPNL-PP--SPPPSPASEQTVTVEEAAGGESALAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRHNSAFPSTTKRAPFSDSFLVQPTSAGSTDRLPHSE
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VKILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEGKAPHWTSASLTEAA--AH
PHSPEMKDQGGSGEGLSRSANGFPYREEEEGAFGEHGSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETVNLPPSPPPSP--
ASEQTAALE---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-EASKMEFPEQQKLPSSFAEPLDKEETEFKMQSKPGEDFEHAALVPQPDTSKTPQDKKDP
QDM-EGEKSPASPFAQTFGTNLEDIKQITEPSITVPSIGLSAEPLAPKDQKDWFIEMPVE
SKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FTLPLDT-
------VKDERVTEGSQPFAPVFFQS-DDKMSLQDTSGSATSKES----SKDEEPQKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVADVPVSEATT-VLGDVHSPAVEG--FVGENISGEEKGTTDQE---KKETSTPSVQ-E
PTLTETEPQTKLEE----TSKVSIEETVAKEEESL---KLKD--DKAGVIQTSTEHSFSK
EDQKGEEQTIEALKQDSFPISLEQAVTDAAMATKTLEKVTSEPEAVSEKREIQGLFEEDI
ADKS-KLEGAGSATVAEVEMPFYEDKSGMSKYFETSALKEDVTRS--TGLGSDYYELSDS
RGNAQ-ESLDTVSPKNQ----QDEKELL-AKASQPSPPAHEAGYSTLAQSYTSDHPSELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKIPCFPIESKEEED
KTEQ------------AK----------V-TGGQTTQVETSSESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSEAVVAESSTGL-PPVA---DDS-QPVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFTAEKEAS-PPSSADKSGLSREFDQDRKANDKLDTVLEKSEEHVDSKEHAKE
SEEVGD-------------------KVELFG--LGVTYEQTSA-KELITTKETAP---ER
A-EKGLSSVPEVAEVETTTKAD-----QGLDVAAKKDDQ---SPLDIKVSDFGQMASGMS
VDAGKT---IELKFEVD--QQLTLSSEAPQETDSFMGIESSHVKDGAKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPETSLIQDEVALKLSVE
-------IPCPPPVSE-ADSSIDEKAEVQMEFIQLPKEE----STETPDIPAIPSDVTQP
-QPEAVVSEPAEV---------RGEEEEIEAEG---EYDKLLFRSDTLQITDLLVPGSRE
-EFVETCP---GEHKGVVESVVTIEDDFITVVQTTTDEGELGSHSVRFAAPVQPEE-ERR
PYPHDEE---------------------------LEVLMAAEAQAEPKDGSPDAPATPEK
E-EVPFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIL---TEQL-------
---------ETIPKEERAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKSEVQAHSPSRKLI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATS-----------
----------------------------------------------GESAQAPSAFKQAK
DKVTDGITKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRT---PGTPKSGILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPYEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELELKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISDDKSGLSKEFDQEKKANDRLDTVIEKSEEHTDSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSLSSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQDTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAPLPLAAEETANLPPSPPPSP--
S-EQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFHDQQELTPSPAEPLEKVEKESEEESKPGEDLKHAALVSQPETTKTSPDKKDM
QDT-EEEKVPPTLFGHTLGASLEDTKQKTEPSLVVPGIGLPAEPSAAKEQKDWFIQMPME
AKKDEWGLVAPVSPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPFDV-
------TKNDIV-AAASPFAPALLQP-DDKKSLEETGSPATAKDS----SKVEEPHMDQP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPASEAVT-SPKDAHISIVED--YVLEKGLGEEKGAIKQESVQIKETPTFREQ-E
SMLTEKEPHLKLEE----QTTVSDEEAVSKESEAP---KLTD--EETGVIQTSTEHAYSK
EEPKGQELPTDILKQDSFPVSLEQAVTDSAVTSKTPEKVMTEPAALSEKSATQELFEEKV
ADKD-NVEGVGAVTSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
REGAQ-ESFDTVSSMYK----NGDKALTAEKDSQPSAVAQEGGYSTLAQSYPSD----LP
EEPISPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVDKAPCFPTESKEEKE
QIKG------------EK----------A-TGEENTQVEPSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASMSADAEVARRKSVPSETVVEESSTGF-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKARRDLVTDLSLIEVKLA
AAGRVKDELSAEKEAS-PPISGDKSGLSREFDQEKKANDKLDTLLEKSEEHADSKEHAKE
TEEA--------G---------D--KVETFG--LGVTHEQASA-KELTVSKDASPLVAEK
AE-KGLSSVPEVAEVEPSQKAE-----PELDFAAKKADQ---GQLDVKISDFGQMASGLH
IDAGKA---AELKLKAT--QDLAPSSTAPQEADAFMGVESGHVKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKEISPESSLIQDEIAIKLSVE
-------IPCAPAVSE-ADLAADERADVQXXXXXXXXXX---XXXXXXXXXXXXXXXXXX
-X--XX-XXXXXX----------XXXXXXXXXXXXXXXXXXXXXXXXXQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPRAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVGLSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------AESAQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTENIKYQPKGGQVQIVTKKIDL
SHVTS-------------------------------------------------------
------------------------------------------------------------
---------------------------------------

---------------------------------MTDNRQDEPKATHWAPGQLSEAS--PL
PHATDMKEQGGAGEGLVHSSNGIPFREAEERAYGERDLQASHSTGKENGINGEMPSADSE
TA--EEVSARIVQVVTADAVAVLRGEQEKEAQLRGPPGDLPLAVEDTTNLPPSPPPSP--
ASEQMGTVEEEL-MWMFKLQLREKYQDETS-------------------------DDKSI
---SKSTTESTTVVLPSLP-----------------------------------------
------------------------------------------------------------
EEASKMGAQETSESTPFCVEAIHTAEDASPTK-----------------------TRKDI
-------------KQNTLDLHAPEIEDKRLPSLPLEEITKPCTPTSPNVPKHNLYEIPDD
SSTLEWSTAQDTSKDSFM--RGKEDFSAVAKNI----EADIPVSTVASKSEIPSMPLDK-
-DEGQYIEDEFSLHSSLPVTDSVLKDNS

PF08377 // ENSGT00530000063491_1_Domain_0 (569, 1964)

-NIAKTEVSSITSTKDSTMDIYKSVNVLSDEQ
EVISEKTSSEEIPSALVSSD---LSSKACHPEAKDDE---DVKSD--------VLKSHPT
DAIAVPPKQDKTDTSTSSDNAEQNKDTLTKESDKT-------------SLGSGMEGTISP
KE---SAKVDEELVTDSFNVTYDSASKS-------CEVPSEAPGMK---GEMSELPLEKL
MSQ-----LKDEKDSEEQKSPVAEDKSGMSTYFETSALKEEIERD--IQQSSDYYELTDV
KEPEYEACS--IPHIAKDEEDEENDDLEQAIEEKVSTPAHEVGYSTLTSVKLQ-------
-ASILPGDRLFTIDPNIYADKSEFLSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFSYARAHDLSPLATDILSNTSGSMDEGDEPELPATTPALEKTISFQNNDAEK--
-----------------------------STEKETFELEPLCESDYQAKEYYKNGTIMAP
DLPEMLDLTGSRSRLDSANADSEATRRKSGPSEIVIDESFVLQ-STEI---AGSSLLVKT
DSQQEELGYCVFNKYTVPLPSPVQDSESLGGGMSTLYEG--------LAVDPFIIEVKLA
AAEKFVIEG--------QDISSEEVCWESELE-KKVSEIKLDTLVEKSEEQSDVKEVSEN
TENVGSPE---EEFSI---AQFDKKSVEESG----EQFPQETE----------------E
-SKVSLADIAGTETEEPSEKAKVSAEESQSILE-----------TSELIEDMSHLKNEIQ
EKIGIAEQDNAIELDSS----LVKDVK-----ETADDEEFAVSKDGTKLLESDLKEKGAK
PDLVHQEAMDKEESYESSGEHEQSQEPAGDVS-----------KDTSLVSTDVQKKDKED
TAPEPQGELTQTVIYSKDDLKQEEADEMQI--IQDEQVVEVSVEKEIPKEH-----ETQK
QLDEEYDEE--------KEETDETEEGDIETTSDA-----------PEQEIEAKIPDEE-
-----PAVGFTDDVAGVIESVVTVDEDFIQVVQTAVDDSEIMAHSVHFATSAPVESEEKL
E----------------------------------LDEDIEEVKDEPREGSPCAPASPQK
E-DTQFTDYK-TETQDDYRDETTIDDSVLDTDSIWVDTQDDDRSIM---TEAI-------
---------EAIPKEDKAERELQR-------------------TYIDKHRKEKPLKS---
--GR----------------------ARISTPERKMAKREPSATCRDEVRRKKAVLKKAE
TTKKADVQPHSPSRKII---LKPAV-RQ--SRPT--HQSCVRR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KPAGCV-----------
-------------------------------------------PIGGESQQTPSAHRQPR
DRVMDGVSRSPEKRSSLPRPSSIHPIRKVYA-DK--EDNSLSTSTSVSSSVRRTTRSEPI
WSRTGKSGTSTPTTPGSTAITPGTPPSYASRTPGTPGTPSYSRTPRTPGTPKSAMLY-SE
KKVAMLRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

IRIFHQPLPDLKNIRSKIGSTDNMKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VKILNEKIDY
SDVQSRCGSKDNISHNAGGGQVQIVSKKINLSHVTSKCGSLKNIRHKPGGGH

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VRIESVKL
DFKEKAHAKIGSLDNAH-HTPGGGNIK-IDSQKLHFREQAKARVDHGAEIVSQSPGRSSA
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGQALVRSANGFPYREDEEGAFGEHGPQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEVQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVAVA---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTALKMEFRDQQELTPSAAEPLDKKEKESEKQSKPGEDLKHAALVSQPETTKTSPDKKDM
QGT-EEEKAPPSLFGHTLVAGLEDMQRKTEPSLVIPGIGLPAEPPAAKEQKDWFIEMPTE
AKKDEWRLVAPVSPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-AEASPFAPALLQP-DDKKSLEETSGPASAKDS----STVEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPASEAVT-SPKDTHILIVDE--CVPEKVLEEEKGAINQDSVPKKETSTLSGQ-E
PTLTEKELQLTLEE----QTTVSDK-AMPQESKPP---KMTE--EETSILQPSTEHTFPK
EEQKSQEPTTDVLKQDSFPVSLEQAVTDSTVTSKTPEKVVTEPAALSEKTDTQDLFEEKV
ADKDKKVEGAGTAASADVDMPFYEDKSGMSKYFETSVLKEEVTKS--IQPGSDYYELSDT
RESAQ-ESFDTVSPMYK----NGDKAPQAEKESQPSASAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPTESKEEEK
RVED------------EK----------A-TGEESTQVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGADDKVRRDLATDLSLIEVKLA
AAGRVKDELSAEKEAP-PHISGDRSGLARELDQERKANDKLDTVLEKSEEHAESKEQAKE
AE--------EAG---------D--EVESFG--AGVTHEQALA-KEPTVSKDASPLVAEK
AE-KGLSSVPEVAEVEPPKKAE-----SELDFAAKKADQ---SQLDVKISDFGQMAAGLN
VDAAKA---TELQPEAP--QDLTPSSTAPQEADVFMGVEPCQVKEGAKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPAVSE-ADAAPEEGADVQMEFIQLPKEE----SKETPDISITPSDVTEP
-LPEAVSAEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGIPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESTQAPSIFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPGE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPYEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELELKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDTRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVIEKSEEHADSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----KGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTT-AGGESALAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLMQPTSAGSTDRLPYSK
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGTFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMRQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FKIEEPHEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELEPKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEAIKS--IEPGSDYYELSDT
RESVH-ESIDTMSLVHK----NGDKEFQTGKEPQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVIEKSEEHADSKEHAKK
TE--------EAG---------E--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAI-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEMKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQSTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQQKDQPAALPLAAEETANLPPSPPPSP--
ASEQTIAVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LPASKMEFHDQQELTPSPAEPLDKKDKESEKQSKPDEDLKHAALVSQPETSQISPDKKDM
QGP-EEEKAPPSLFGHPLGAGLEDTTQKTAPSLVVPGIGLSAEPPATKEQKDWFIEMPTE
AKKDEWGLAAPISPGPLTPMKGKDVLEDIPKWEGKQFDSPMPSPFQAGS---FTLPLDV-
------MKNEIV-AEASPFAPALLQP-DDKKSLEETSGPATAKDS----SKVEEPHKDTP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPAPEAIT-VPKDAHIPTMEE--CVSEKVLGEEEEEIKQESAQKKE------Q-E
VTLTEKESPLKLEE----KTTVSDKEAMPKESEPP---KLAD--GETGIIQPCVEHTPSK
EEQKGQEPTTDPLKQDSFPVSLEQAVTDSAVTSKTLEKVMTEPAAVSEKSAAQDLFEEKV
ADKDIKMEGVGAAASAELDMPFYEDKSGMSKYFETSALKDEVTKS--IQPSSDYYELSDT
RESVQ-ESFDTVSPVCK----NGDKGLQVGKEPQPSAPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEG------------EK----------A-AGEESTQVETTCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKMRRDLATDLSLIEVKLA
AAGRVKDEFGAEKEVS-PHTSGDRLGLGREFDQERKANDKLDTVLEKSEERAAAKEHTKA
TE--------EAS---------D--KAEPFG--SGGPHEHIPT-KELTVSEDASPPADEK
AE-KGLSSVPEVAEVEPSKKAE-----PELDFVAKKADQ---GQLDVKISDFGQMASGLT
VDTGKA---TELKLEAT--QDLTPSSAAPQEADVFMSIESGHVKEGTKVSETEIKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPAVSE-ADFIPEERADVQMEFIQEPKEE----SKETPDISVTPSDVTEP
-LPEATGAEPAEA---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHAEE--------------------------ELEGEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTATGGESTQAS----
-----------------------------------------------------SVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSDTKENGINGELTSADRE
TP--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTVPVEEDE-GAEDQVGPLHRFPSHEPATSGERRRLLAPSISVSVPDDDPSNSDEEY
YEHPLFSSQWTSSVLPSVPAQSAEAHLGQEKEEETLESPMAEEEKPATLPEKECGA----
AKASDQPKGLSEGQVESSSEAQVVAEENAPAGAAQEKSVKEV-TEVSPEVKTPSSAGEGV
LTASKMEFHDQQELTPSPTEPLDKKEKESEKESKPGEDLKHAALVSQPETTKISPDKKDM
QGA-EEEKEPPALFGHTLGASLEDMKQKTEPSLMVPDIGLPAEPPATKEQKDWFIQMPME
TKKDEWGLVAPISPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-AEASPFAPALLQP-DDKKSLEETGSPATAKDS----SKVEEPHKDQP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPASETIT-SPKDSHLSIVEK--HIPEKVLGEEKGATQQESVQITETPILSGQ-E
SILTEKEPHLKLEE----KTTISEKEAMPKESEPL---KLTD--EETGVIQPSTEHTYSK
EEQKGQEPPTDILKQDSFPISLEQAVTDLAMTSKTLEKVMIEPAAPSEKSATQELFEEKV
ADKDNKVEEVGAIPSAELDMPFYEDKSGMSKYFETSALKEEVTKS--TQPGSDYYELSDT
RESAQ-ESFETVSPMYK----NGDKGLPAEKESQPSAPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVDKAPCFPTEGKEEKE
QIEG------------EK----------A-TGEESTQVETTCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDTENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSAEKEAA-PHISSDKSGLSKEFDQERKANDKLDTVLEKSEEQADSKEHAKE
TE--------EAE---------D--KVEPLG--LAVTHEQASA-KEPTVSEDASPLLAEK
EE-KGLSSVPEVAEVEPSKKAE-----PELEFAAKKADQ---GPLDVKISDFGQMASGLN
VEAGKA---AELKLEAT--QDLIT-STAPQEADAFMGVESGHVKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------VPCAPAVSE-ADLAADERADVQMEFIQLPKEE----SKETPDISITPSDVTEP
-LPEATGAEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPRAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKADKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAAGESAQAPSVFK
QAKDKVSTSTLSKIPALQGSTKSPRSSSACPNTTKRATFSDSLLTQPTSAGSTGRLPYSE
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------DL
LAATKMEFRLQEGTCPFAAEPLDTKQRESGKDSKTVEQPKYDALVPQSAKTEATD-KKDS
ESK---DKVLSPPSEWILKT---DLQKKGEASFAEPA----TKPPASQEQEHLSSQLPGE
SRVEERTAAVPSSTDQVMAIKSHDNLKDIQGGAI----------SHGES---FLLLSEPK
AE---AAKRELP-SGPSPALPQELSLKDSFKTHQELADQLFAKDL----SKEVQIHRDRT
FSLPEVSAVTID----------GLKTPSTPKIPPWGEEKDMTKDESDEDGKITTKSEVKT
PSLAKTDFQKDGEA-----------------KKSP---DTLKAEKETDQSGLSAAADVKK
EVQQSTQVPPAKLSHELTPEKTME-H

PF08377 // ENSGT00530000063491_1_Domain_0 (747, 1964)

PDTTQLSRVSEKAPEAPGLTTEKTPTLEASHEKD
VKKDTEED--KTSVSAPHQMKEEEDQSGMSKYFETSALKEEAFKADGLKQSSDYYELSDT
KESKY-DPYQRGRLIPE----DEEEEEEEEFNQQQNLHTREMGYSTLAQSYAPD----TS
EEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIESREEDE
HIEE------------EK----------V-TAEEKVQPQTLAEPSFQAKDYYKNGAVLAP
DLPEMLDLAGTRSRLASVSADAEVAQKKSVPSDTVVEDSSTAL-PPVT---NENHVILKA
ESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRGLAPDLSLIEVKLA
AAEKSKEDFLSEKDLG-QHG---ESILVRGFEEEK--KEKLDTVLEKSEEQIESKELGRK
EESVAS-------------------KV---HLPADTVYDRISA-SELAIEKDSVCLLMEK
E--KTLSVVPEIAEIDAPVKPDYNAIKHDMEVAARRADQEYQSKLDAKISEVVSLPSGKD
KASLKK---AEPEPKDAQQKEETIFSREAKDADILSKTEPSYVKDITKLSETEIKEKVPK
PDLVHQEAVDKEESYESSGEHDQTQESLNGEPVKPEDIKAE-HPKPPVSGEEMPTQLPAK
-------ETSVELLFPKAEPLREEPAEIQMESIPQPAEG----AEETLDTSVKPLETQKL
LPCELAAGAPKGE----E-----YEEEEVEAGQEAKEEDKEHLVSE--MPPDFGKPAAEE
-MGAKGSPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIETGD
SQAEE----------------------------ELDV---EEVEVEPKEGSREAPASPQR
E-EILLTNYK-TETCDDYKDETTIDDSIMDTDSLWADTQDDDRSIM---TEQL-------
---------ETVPKEEKAERELRR-------------------SSLDKHKKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKII---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KQTAAG-----------
----------------------------------------------GETNQAPAVFKQAK
EKLSDGVSKSPEKRSSLPRPSSILPPRRGVSGDRDREENSLSLTASLSSSVRRTTRSEPI
RSRTGKSGTSTPTTPGSTAITPGTPPSYASRTPGTPGTPSYSRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRVINQPLPDLKNVRSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HVPGGGNVKQIDSQKLNFREHAKARVDHGAEIITQSPGRSSM
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSTAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TETSPFAPAFLQP-DDKKSLQQTSGPATAKDS----FKIEEPHEAKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LPKDAHIPVVEE--HVMGKVLEEEKEAINQETVQQRDTFTPSGQ-E
PILTEKETELKLEE----KTTISDKEAVPKESKPP---KPAD--EEIGIIQTSTEHTFS-
-EQKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQAEISCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--EIETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEIAEVEPSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRA---TELKLEAT--QDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHETIVSEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---SEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTALKMEFHDQQELTPSAAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TETSPFAPAFLQP-DDKKSLQQTSGPATAKDS----FKIEEPHEAKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LSKDAHIPVVEE--HVMGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKETELKLEE----K-TISDKEAVPKESKPP---KPAD--EEIGIIQTSTEHTFS-
-EQKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------T-TGEESTQAETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHVSGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--EIETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEIAEVEPSKKVE-----QGLDFAV-------QDQLDVKISDFGQMASGLN
IDDRRA---TELKLEAT--QDMSPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPGISITPSDVAEP
-LHETIVSEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---SEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYEDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVEEE-------------------------------------------------
--------------------------------EETLESRMAEEEKPAALPEKECGA----
AKSSDQPKGLSKGQMESSAEAQIVPEESAPAGAPHEKSVKEV-KEVSPEVKTPSSAGEDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FNIEEPCEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELELKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSPMHK----NGDKEFQTGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISDDKSGLSKEFDQEKKANDRLDTVIEKSEEHTDSKEHAKK
TE--------EAG---------D--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGIKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDLSITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLMQPTSAGSTDRLPYSK
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AQ
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQPKDQPPALPLAAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFHDQQELTPSPAEPLDKKEKEPETQRKPGEDLKHAALVSQLEMTETSPDKKDA
QGT-EEEKAPPTLFGHTLGASLEDTKPKTEPSLVVPDIGLPAEPAAAKEQKDWFIQMPTE
AKKDEWGLVAPVSPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPFDI-
------SKNEIV-AAASPFAPALLQP-DDQKSLEETGSPATAKDS----SQVEEPQKDQP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKIAEAPAPEAVA-APKDAHVSIVEE--CVPEKVSGEEEGVIKEESVQIKETPTLSGQ-E
STLAEMEPHLKLEE----QTTISDKEAVPKESEPP---KLID--EETNIIQPSTEHTYSK
KEEMGQEPPTDILKQDSFPVSLEQAVTDSAVTTQTPEKIMTEPTALSEKSATQELFEEKV
ADKDHKVE-VGAVTSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPVSDYYELTDT
RESAQ-EAFDAVSPMHK----DGDKTLP-EEEPQPSAPAQEAGYSTLAQSHPAD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVDKAPCFPTESKEEKE
QVKE------------EK----------D-TGEENARVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADTEVARRKSVPSETVLEESSTGL-PPVT---DENHIIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKARRDLATDLSLIEVKLA
AAGRVKDEVSAEKEAS-PPISGDKSGLSREFDQEKKANDKLDTVLEKSEEHADSKEHTKE
TE--------DAG---------D--EVETLG--LGVTQEQASA-RELMISKDASPVMAEK
AE-KVLSSVPEVAEVEPSKKAE-----PELDLAVKKAEQ---GQLDIKISDFGQMASGLH
VDAGEA---AELKLEAT--QDLAPSSTAPQEVDAFMGVESSHVKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPVVSE-ADVAADERADVQMEFIQLPKEE----SQETPDISITPSDVTEQ
-LPEAARAEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGAPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-GRR
PSPHAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVGLSEYK-TETYEDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKGSFHNHF
FINV--FEKKLPNREFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTT-AAG----------
----------------------------------------------AESPQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
----------------MCLSADFPVGYL----LG-------WT------SSHFMFFCYCL
FA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETAHLPPSPPPSP--
ASEQTVAVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LSASKMEFPEQQKMTSSLTEPLDKGEKEMEMQSKPGEDFEHAALVPQPETTKTPQDKKDL
QGT-EGEMSPPIPLGHTFGTNLEDIKQNTEPSITVPSIGLSAEPPAPKDQKDWFIEMPME
PKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FALPLDM-
------IKNEIVTEASQPLVPVFFQP-DDKTSLQGTSDLATTKDS----SRDDVLQKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DNVADVPVSEAAT-LPKDTHSPVMEG--YVGEGVSGEEKGATNQE---KKETSTPGRQ-E
PTLTENEPQAKLEE----KLVVPIEEAVAKEHELP---KLRE--DEAGVLQTSTEHSFSK
EEQKGQEQVADELKQDSFPVSLEQALSDAAMTFGTLEKVTPESEAVPEMRETQGLFEENT
AVKD-KFEGVGSATVAEVGMPFYEDKSGMSKYFETSALKEEVTKS--KELGSDYYELSDA
RGSAQ-ESADTGSPKHQ----DGEKEVQA-KESQPSAPTQETGYSTLARSYPSD---ELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKVPCFPIESKEEEE
KAEE------------AK----------V-TGEQTIQVETPSESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSAEAEVARRKSVPSEAVVAESSTGL-PPVA---DESQAAVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFPAENEPS-APTPADKSGLSRELDHDRKANDKLDTVLEKSEEHVESKEHAKE
TE--------EGG---------E--KVDLFG--LGVTCEQASI-KELTTAEDTSP---EK
AE-KGLSSVPEVAEVEPTTKAD-----QGLDFAAKKAEP---SQLDIKVSDYGQMASGMN
VDAGKA---TELKFEMS--PELALSSKEPQEEDSFMGVESGHMKEGAKVNETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEVALKLSVE
-------IPCPPPVSE-ADLSTDEKAEVQMEFIQLPKEE----STETPDIPAIPSDVTQP
-QPEAIVSEPAEVP----------SEEEIEAGG---EYDKLLFRSDTLQITDLVVPGSRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALAQPEE-ERR
PRPHDEE---------------------------LEVEMAAEAQAEPKDGSPDAPATPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------DTIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------GESAQAPSALKQAK
DKVTDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTENIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2270)

VRILSKKIDF
SKVQSRCGSKDNIKHSAGG------------------------------

ENSGT00530000063491_1_Linker_3_5 (2270, 2273)

GGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MADERKDDGKAPHWTSASLTEA-AAH
AHPPEMK--D---------------------QGG-----AGEGLSRSANGFP----YREE
E-EGAFREHGSQGTYSDTKE-NGINGELTSADRETAEEV-SARIVQVVTAEAV-------
---------AVLKGEQEKEAQQKDQSAALPLAAEETAHLPPSPPPSPASEQAVAVEE---
------------------------------------------------------------
----------------------------------------------AAS-----------
----------------------------------------------GESAQAPSALKQTK
DKVTDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAPLTEAS--AH
AHPPEMKVQGGAEEALVQSANGFPYREDEEGAYGEHRSQDTYSKTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKETQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQIVTGE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFQDQQELTASTTEPLDKKEKESEKQSKPGEDLKHAALVSQPETTQTYADKKDM
QGP-EEEKAFPTLFGHTLVSSLEDTKQKIEPSLVVPGIDLPSVPPTPKEQKDWFIEMPME
TKKDEWGLAAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------LKHEIV-PETSPFAPAFLQP-DDSQFLQETSGPATAKDS----SKIEEPHRDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPASEAIT-LPKDAHIPVMEE--CVMEKVLEKEKGGIHQENVQKKDTFSPSGQ-E
PVLTEKEPQLKLEE----KMAISEKEAVPKESRPL---ILAD--EETGIIQTSTEHVFSK
DEQKGQDSATNMLKQDPFPVSLEQAVTDSVMTSKAADKVMAEPATPSEKSATQEVFEAKV
ADKDSKVEGVGATASVELDMPFYEDKSGMSKYFETSALKEEITKS--IEPGSDYYELSDT
RESAH-ESVEAISPMHK----NGDTGFQAEKESQPSAPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKVPCFPTENQEE-E
QIEK------------EK----------A-TREENTQVEASCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSEESGSFYEGTDDKIRRDLATDLSLIEVKLA
AAGRVKDEFSSEKETS-LRISGDKSGLGREFE-ERKANDRLDTVLEKSEEHADLKEHVKK
TEED--------G---------D--KVETFG--IGVTCEQALA-S-------------SE
ESEKGLSSVPEVTEVEPPKKAE-----QGLDFAAKKVAQ---GQLDVKISDFGQMASGLD
VDAGKA---TELKVEAT--QDLTPSSKVSQEADAFMGVESGHLKEGLRVSEMEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIALKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQLPKEE----SKETPGISITPSDVTEP
-LLEAVASEPAEVQ----------SEDEIEAQG---EYDKLLFRSDTLQITDLGAPGVRE
-EFVETCP---GEHKGVIESIVTIEDDFITVVQTTTEEGESGSHSVRFAALEQPEL-KRR
PAPHGDE---------------------------FEMEEAAEAQAEPKEGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------GESALAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPRSAVLVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEGKAPHWTSASLTEAA--AH
PHSPEMKDQGGAGEGLSRNANGFPYREEEEGAFGEHRSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASEQTATVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPEQEKFPSSFAEPLDKGEMEFKMPSKPGEDFEHAALVP--DTSKTPQDKKDL
QGM-EGEKLPPVPFAQTFGTNLEDRKQSTEPSIVMPSIGLSAEPPAPKEPKDWFIEMPTE
SKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FTLPLDT-
------MKNERVSEGPRPFAPVFFQS-DDKVSLQDPSALATSKES----SKDEEPLKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVADVSISEVTT-LLGNVHSPVVEG--YVGENISGEVKVTTDQE---KKETSAPSVQ-E
PTLTETEPQTKLDE----KSTVSIEEAVAKEEESL---KLRD--DKTGVIQTSTEQSFSK
EDQKGQEHTIDELKQDSFPISLEQAVTDAAMTSKTLGKVTSEPEAVSERREIQGLFEEKT
ADKN-KLEGAGSATIAEVEMPFYEDKSGMSKYFETSALKEDMTRS--TELGSDYYELSDS
RGSAQ-ESLDTISPKNQ----HDEKELQ-AKASQPSPPAQEAGYSTLAQSYTPDHPSELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKMPCFPTESKEEED
KAEQ------------AK----------V-TGGQTIQVETSSESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSEAMLAESSTSL-PPVA---DESPVTVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFTAEKEAS-PPTSADKSGLSREFDHDRKANDKLDTVLEKSEEHIDSKEHAKE
SEEMGG-------------------KVELFG--LGITYDQAST-KELITTKDASP---EK
T-EKGLSSVPEVAEVEPTTKAD-----QGLDFAATKAEP---SQLDIKVSDFGQMASGMN
VDAGKA---IELKFEVA--QELTLSSEAPQEADSFMGVESGHIKEGGKVSETEVKEKVTK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPETSLIQDEVALKLSVE
-------IPCPPPVSE-ADLSTDEKGEVQMEFIQLPKEE----STETPDIPAIPSDVTQP
-QPEAIVSEPAEV---------PSEEEEIEAGG---EYDKLLFRSDTLQISDLLVSESRE
-EFVETCP---GEHKGVVESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEE-ERR
PRPHDEE---------------------------LEVEMAAEAQAEPKDGSPDAPATPEK
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIL---TEQL-------
---------ETIPKEERAEKDARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKSEVQAHSPSRKLI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAS-----------
----------------------------------------------GDLAQAPGAFKQAK
DKVTDGISKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRT---PGTPKSGILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AQ
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQPKDQPPALPLAAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFHDQQELTPSPAEPLDKKEEEPETQRKPGEDLKHAALVSQLETTKTSPDKKDA
QGT-EEEKAPPTLFGHTLGASLEDTKPKTEPSLVVPDIGLPAEPTAAKEQKDWFIQMPTE
AKKDEWGLVAPVSPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPFDI-
------SKNEVV-AAASPFAPALLQP-DDQKSLEETGSPATAKDS----SQFEEPQKDQP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKIAEAPAPEAVA-APKDAHISIVEE--CVPEKVSGEEKGVIKEESVQIKETPTLSGQ-E
STLAEMEPHLKLEG----KTTISDKEAMPKESEPP---KWID--EETNIIQPSTEHTYSK
KEEKGEEPPTDILKQDSFPVSLEQAVTDSAVTTQTPEKIMTEPTALSEKSATQELFEEKV
ADKDHKVE-VGAVTSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPVSDYYELSDT
RESAQ-EAFDAVSPMHK----DGDKTLP-EEEPQPSAPAQEAGYSTLAQSHPAD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVDKAPCFPTESKEEKE
QVKE------------EK----------D-TGEENARVETSCESPFRAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADTEVARRKSVPSETVLEESSTGL-PPVT---DENHIIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKARRDLATDLSLIEVKLA
AAGRVKDEVSAEKEAS-PPISGDKSGLSREFDQEKKANDKLDTVLEKSEEHADSKEHTKE
TE--------DAG---------D--EVETLG--LGVTQEQASA-RELMISKDASPVMAEK
AE-NVLSSVPEVAEVEPSKKAE-----PELDLAVKKAEQ---GQLDIKISDFGQMASGLH
VDAGEA---AELKLEAT--QDLAPSSTAPQEVDAFMGVESSHVKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPVVSE-ADVAADERADVQMEFIQPPKEE----SQETPDISITPSDVTEQ
-LPEAARAEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGAPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-GRR
PSPHAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVGLSEYK-TETYEDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEAQR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTGDSG----------
----------------------------------------------AESPQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTSSAAEPLDKKEKESEKQSKPGEDLKHAALVSQPETTKTYPAEKDM
QGT-EEEKAPPALFGHTLVANLEDMKQMTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPVSPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKSEIV-TETSPFAPAFLQP-DDKKSLQQTSGPATAKDS----SEIEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEVPPSEAMT-LPKDAHIPVVEE--HVMGKVLEEEKEAIKQETVQQKDTFTPGGQ-E
PTLTEKEPELKLEE----KTTISDKEAVPKETRPP---KLAD--EETGIIQTSTEHTFS-
-VQKGHEPTMDMLKQDSFPVSLEQAVTDSAVTSKTLEKAMIEPSALIEKSSIQELFDMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSVLKEEATKS--IQPGSDYYELSDT
RETVH-ESIDTMSPMHK----NGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QMEK------------VK----------A-TGEENTQVETTCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFGVDKEAS-PPISGDKSGLSKEFDQERKASDRLDTVLEKSEEHADSKEHAKK
TE--------EAG---------D--KVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVEPSKKAE-----QGLDFAANKAVQ---GQIDVKISDFGQMASGLN
IDARKA---TELKLEAT--QDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKEISPESSLIQDEIAIKLSVE
-------IPCPPTVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-VHEAIVSEPAEV---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGASGARE
-EFVETCP---GEHKGVIESIVTIEDDFITVVQTTTDEGESGSHSVRFAALDQPEV-ERR
PSPRDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESAVAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MADERKDEAKAPHWTSAQLADA-SAH
PHPPEIK--D---------------------QAGA-----GEGLVRSANGFP----YRED
E-EAAYGDHGAQGPYSDTKE-NGINGELTSADRETAEEV-SARIVQVVTAEAV-------
---------AVLKGEQEKEAQHKDQPTGLPLAAEETANLPPSPPPSPASELTVPLEE---
--AT----------------------GGES-------------------TQAPSVFKQAK
DK-----VSHPTLSK------IPALQGS--TKPP--RFSTAYSSTAERGT----------
--------------------------------------FSDSFLTQPNSAGSTERFPNSK
SGNKDGMTKSPEKRSALPRPSSILPPRRGVSGDR--DENPFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSFPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKTDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDVSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSTQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQSTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQQKDQPAALPLAAEETANLPPSPPPSP--
ASEQTITVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LPASKMEFHDQQELTPSPAEPLDKKDKESEKQSKPGEDLKHAALVSQPETTKIFPDKKDM
QGP-EEEKAPLTLFGHTFGAGLEDTKQKTEPSLVVPGIGLSAEPPVPKEQKDWFIEMPME
AKKDEWGLAAPISPGPLTPMKGKDVLEDIPRWEGKQFDSPMPSPFQAGS---FTLPLDV-
------MKNETV-AEASPFAPALLQP-EDKKSLEETSGPATAKDS----SKAQEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPAPEAIT-LPKDAHIPTMEE--CVPGTVLGEEKGAMKLESAQIKE------Q-D
VVLPEKESLLKLEE----KITVSDKEAMPKESEPP---KPTD--GETGIIQPCMEHTLSK
EEQKGHEPTTEPLKQDSFPASLEQAATDSAVTSETPEKVTTAPAAVRDKSAAQDLFEEKV
AGKDVKLEGVGAAATAELDMPFYEDKSGMSKYFETSALKDEVTKS--IQPGSDYYELSDT
RESVQ-GSFETVSPVCK----NGDKGLAAGKEPQPSPPAQETGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPSFPVESKEE-E
QSEG------------GK----------A-AGPPTTQVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEESVTGL-PPVT---DENHVIVKT
ESQLEDLGYCVFNKYTVPLPSPVQDSETLSGESGSFYEGTDDKMRRDLATDLSLIEVKLA
AAGRVKDEFGAEKEVS-PRTSGDKSGLSREFDQERKANDKLDTVFEKSKEHADAKEHAKA
TE--------EAS---------D--QAETFG--LGVTYEPAST-KEPTVSKDATPPAAEK
AE-KGLSSVPEVAEVEPSKKAE-----AELDFVAKKAEQ---APLDVKISDFGQMAAGLT
VDAGKA---TELNLEAA--HGLIPLSPAPQEADAFMSVESGHIKEGLKVSETEIKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKEISPESSLIQDEIAIKLSVE
-------IPCARAASE-ADLVPDERADVQMEFIQQPKEE----SKETPETSVTPSGVAEP
-LLEATGAAPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTEEGESGSHSVRFAALEQPEV-ERR
PSPRAGE--------------------------ELEAEEAAEAQAEPKEGSLEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEDKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTATGGESTQASSVFK
QAKDKVSNSTLSKIPALQGSSKSPRSSSACLSTSQRASFSDSFSIQSTSAGSTDRLPYSE
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MEEEEEAMQGPVIEEEKSTGLPVKEPGSALGP
VAPYEHPEGPREGPVDASLKAKMAPEERDPTGAPHGESIKEEAKDVSLELKVPPSD----
REAPKMESHDQEHPTPLPTKPGYEKEWESEKESQVSGQPKPDTQVVQPAEPETGARREET
RGE-EKETAPVIGLGQTWGAHPE-----QDPSSIVPTGGFPVEPLVRK-EQDWPMGIPTE
SKPDQWSTVTLQSPGPLTTMKEKDDFTALTKWDEKVLATPQQ----SGG---FPLSPGPK
TDEARATRREFL--PETPFAESEIHQPEGRKSKPEQTHPLVAKEA----LREEPFYKYKS

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMGDMPMSTVIT-QSMEVHKLTIRESHGQRGCGVGEDKDIPRWENDLRKEHFLPNGQ-K
FALFESEPYRKPEEKSSVLVSLPQ------DSK-----LLKGLDEEKSTTRSLGGQTIKK
EEPPSKGAQVDQFRRDSFPGAQGRDLMLAAALSETLDKMPVAPSPRSD--PARSLSQERE
IGKDIRADKAGAPP-PTEERPLDEDKSGMSKYFETSTLKEEATKS--LQQDSDYYELSDS
KESAY-ESYDTVAPMFK------------DGDQESSAPACEVGYSTLAQGYPSD----IA
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPGLEKAPGFPTEGREEKE
EEGEEEEEEEEEEEVEEAEQAEGQKKAGKAVEVESSQVESPSESPFLAKEYYKNGAVMAP
DLPEMLDLAGTRSRLASVSADTESARRKSVPADVGGHDSGAGVLSPIG---NKNHVAVKD
DSQMEDLGYCVFNKYTVPLPSPVQDSENLQGDSGLFYEGADDKLRRDLATDLSLIEVKLA
ATGRVKQDVGGEKEPS-PPVSGDKAGLSRELDQDRKATDKLDTVLEKGEEPMDSKETLLP
EEHGKL--GPGEVV----------TKVEMVSSEPAV--D-LASIQVMTQSQDTSPFMTEK
VE-PLLGSVPEVAETEPLPKAE-----PRTDPSA-KADP---SQPVVQVSDFGSTAAEQD
GASQGP----------AAQQEGAGLARGGQDVELLVGAEAGDGKEGTRGSEAEIKEKVAK
PDLVHQEAVDKEESYESSGEHDVTPEGGAGEPSKPDEGKKEPAKEPPTLPDEVTVRALEA
E------LP-----PSSVDAVLVEGADIQMEPIQQPKRD----SQEAPGISITPSEALEP
TLLKPGSEASADE--------NKEGQEEVEARG---ESDRLLFRSETLQLADLSIPTDRE
-ESEKRGVEDVPEHKGGIESVVTIEDDFITVVQTTTDDGESGSHSVRFAALDQAEVESRP
SPPGGEEEEEEEEEEEEEGGGGGGGEEEEEEASEPEAEELMDDRPEPKEGSPEAPASPDK
EEEVGLSEYK-TETLDDYRDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETVPKEEKSEKEARR-------------------PSLDKHRKEKPFKA---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRKKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KQTGA------------
-----------------------------------------------ESAQVPSVFKQAK
EKVADGAAKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSVRRATRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYARTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVRSKIGSTENIRYQPKGGQVRTDHAHG--
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------

---------------------------------MADDRKDEAKAPHWASAQLTEAP--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEAAFGEHESQGAYADTKENGINGELXXXXXX
XXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFPEQQELASSAAEAVDKKEKESEKQNKPGDDLKHAALVSQPDTTEIPTDKKNM
Q----EENASISLFGHTFGASSEDMKPTTDPSLVVPSIGLPAEPLTPKEQKNWFIEMPTE
AKKDEWGLVAPISPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQAGS---FTLPLGV-
------IKNEIV-AGSSPFASALLQLERRRSLVGEGSGLVTAKDS----TKTEEPQKNKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAEAPVSEVFA-SLKDAPISIVEE--YVLEKVLEEDKEALKQDSVPKEELSTLTGE-E
STHTEKEPQLKQEEITTS-----DKVASPEERE------HSNPDEKMGLIQILTELTFTK
-EQKGQESTTDILKQDSFPVSLEKA--------------APEPVVLNEKSTIQELFEENV
SDKDSKFEEIEAATSVEPDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
RESAP-ESFDTVSPMYK----DEDKGLQAGKDSQPSVPAQEAGYSSLAQSYPPD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIESKEEEE
QIEE------------EK----------S-AREENTQFESSCESPFLAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADGEVARRKSVPSETVAEERSPDL-PPVT---DDNHTIVKT
DSQPEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTEDKIRRDLATDLSLIEVKLA
AAGRVKDESSAEKETS-PQTSSDKLGLGREFDQERKVNDKLDTVLEKSEEHAKETEETED
-------------------------KI--------ETYEPVSG-KELTVSKDASPLIAEK
AE-KGLSSVPEVAEVEPSRKAE-----LGMDFDAKKPDQ---GQIDVKISDFEQMATGLG
LDTERA---TELQLEAA--KDLTPSSPTPQETDGFMGVESSHMREGAKVSETEIKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKEISPESSLIQDEIAVKLSVE
-------IPCATAIAE-ADLVIDEKVDVQMEFIQLPKE-----SKETPDISITPSDVTEP
-LLEALSAEPAEP---------QIEEEEIEAQG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEHPEV-ERR
PSPHAEE--------------------------ELKEEEAAEAQAEPRDGSPEAPASPER
G-EVAVSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------DTIPKEEKADKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSSDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKRKTTAAG-----------
----------------------------------------------GESTQASSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSVRRTTXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRIVNTKIDL
SKVQSRCGSKDNIKHSAGGGNXXXXXXXXXXXXX--------------------------
--XXXXXXXXXGLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEGKAPHWTSASLTEAA--AH
PHSPEMKDQGGAGEGLSRNANGFPYREEEEGAFGEHRSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQYKDQPAALPLAAEETANLPPSPPPSP--
ASEQTATVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPEQQKFPSSFAEPLDKGEMEFKMPSKPGEDFEHAALVP--DTSKTPQDKKDL
QGM-EGEKLPPTPFAQTFGTNLEDRKQSTEPSISMPSIGLSAEPSAPKEPKDWFIEMPTE
SKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FTLPLDT-
------MKNERVSEGPRPFAPIFFQS-DDKVSLQDPSALATSKES----SKDEEPQKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMADVSISEVTT-LLGNVHSPVVEG--YVGENISGEDKVTTNQE---KKETSVPSVQ-E
PTLTETEPQTKLEE----KSTVSIEEAVAKEEESL---KLRD--DKTGVIQTSTEQSFSK
EDQKGQEHTIDELKQDSFPISLEQAVTDAAMTSKTLGKVSSEPEAVSERREIQGLFEEKT
ADKN-KLEGAGTATITEVEMPFYEDKSGMSKYFETSALKEDMARS--TELGSDYYELSDS
RGSAQ-ESLDTISPKNQ----HDEKELQ-AKASQPSPPAQEAGYSTLAQSYTPDHPSELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKMPCFPIESKEEED
KAEP------------TK----------V-TGGQTTQVETSSESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSEAMLAESSASL-PPVA---DESPVTVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFTAEKEAS-PPTSADKSGLSREFDHDRKANDKLDTVLEKSEEHLDSKEHVKE
SEEMGD-------------------KVELFG--LGITYDQTST-KELITTKDTSP---EK
T-EKGLSSVPEVAEVEPTTKAD-----QGLDFAAKKAES---SQLDIKVSDFGQMASGMN
VDAGKA---IELKFEVA--QELTLSSEAPQEADSFMGVESGHTKEGVKVNETEVKEKVTK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPETSLIQDEVALKLSVE
-------IPCPPPVSE-ADLSTDEKGEVQMEFIQLPKEE----STETPDIPAIPSDVTQP
-QPEAIVSEPAEV---------PSEEEEIEAGG---EYDKLLFRSDTLQISDLLVSGSRE
-EFVETCP---GEHKGVVESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEE-ERR
PCPHDEE---------------------------LEVEMAAEAQAEPKDGSPDAPATPEK
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIL---TEQL-------
---------ETIPKEERAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKSEVQAHSPSRKLI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAS-----------
----------------------------------------------GELAQAPSAFKQAK
DKVTDGITKSPEKRSSLPRPSSILPPRRGVSGDR--EEHSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRT---PGTPKSGILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MAEDRKDEAKAPHWTSGQLTEAA--SH
PHSPEIKEQSSAGAGLVRSANGFPYQEGEEPGLGSREQPGSYARSKENGINGELSAGDRE
TAATEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSP--
ASEQTGALE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
IAATKMEFHVQEGTCPFTTDPLDTKQQESGKDSKT-EQPKHDALVPQPAKAEAT-DKKDS
QSK-DKEKMPSPLSEQILET---DSQKKLEASFAEPSAKL----PISQVEKDLPSELPKG
SKTEERTADKPSSSNQVVSVTFKDDLKDVQDLAISH----------DGSSLFTSEPKT--
----EAAKSELP-SDPSLAIPQDLPLKDSAKTKPEPADQLFAKEL----AEDEQT

PF08377 // ENSGT00530000063491_1_Domain_0 (596, 1964)

HRGMT
LTLQEVSTVT----------IDGLKTPSTQKIPAWGQEKDMTKDETDEEERYDFYDKGEA
RILDDAKFTTKTEV----ETLAQDKADFPKDGEIKM-SDLFKAEKEMDQSGLQATT----
-----------ATKKDMQPSTELSQITE--KSP-------QAPSSTTDKTLTPEPSQEKD
VKKETKED--KESVSATHEMKTEVDRSGMSKYFETSALKEEAFKTDALKQGSDYYELSDT
KESAY-ETYRADRLIPEDKE-EEEEELQMELDQQQGMPGHEIGYSTLAKSYTPD----KS
EEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDD-YLPATTPAMERAPCFPIDSREEDE
HIEE------------EK----------A-MTEEKVQPETLVESPFPAKDYYKNGAVLAP
DLPEMLDLAGTRSRVASVSADAEVAQKKSVPSDAVVEDSSTAL-TSVT---DENHVTLKA
ESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRSLAPDLSLIEVKLA
AAEKSKEEFLGEKDLT-QHA-TGESLLARDFEQEK--KEKLDTVLEKSEDQADLKEEMKE
EVVSDK-----------------------VHVPDDTTYDRILA-TQVTAERDAISFLMEK
E--KTLSVVPEIAEIEAPIKPDYNAIKHDMEVAARRADQEYQSQLDSRISEVVSLPSGKD
KAPVKK---TEPEPKETQQKDQIILSREAKDADLLSKTEPSYVKDSTKLSETEIKEKVAK
PDLVHQEAVDKEESYESSGEHDQTQESLNGEPLKQEDIKGEA-PKPSVSEEEVSTQLPAK
-------EPSTELLLPKAEPPQEEPAEIQMESIPQPPEE----TEKIPDTVVKPTEVQTL
LPSEMTAK-ATKRE--------DHEEEKLEGGQEEKEEDKQHLISEIPPEMDFGKPTDEE
-LLAKVCPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIEAVD
SQAEE----------------------------ELEIEEVVDIQAEPREGSPEAPASPER
E-EILLTDYK-TETCDDYKDETTVDDSIMDTDSLWADTQDDDRSIM---TEQL-------
---------ETVPKEEKAERELRR-------------------SSLDKHKKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSR-KI--ILKPAI-KY--TRP--THLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KQTAAV-----------
----------------------------------------------GETNQAPGVFKQAK
EKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPI
RSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRVINQPLPDLKNVRSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLKSPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKTPHWTSSQLAEAS--SH
PHSPELKEQAGAGDGIVRSANGFPYREEEEGGYGDHGQQGTYSRTKENGINGELTSAERE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEGQPKDQPAGLPIAVEESANLPPSPPPSP--
ASEQTGTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LSASKMEFPEQA--LALTVEPLDKKEKETEKGSKLAELPKHDALVTQPAQPETA-DQKDV
HGK-QDGKAPLTPFEQTFGEELEYMQQKSEPIPSEPDVGFPTETVFQKEQKDLSIEVP--
--KEEWSTYSQLSPGPLTSMKERYEVEEIPKWAEKHLDSPKPSPFGSVS---FPLPSDA-
------TKDKLVSET-----PETPKP-EDKKPKVESSGPQIAKEI----PKDEQNLMEKT
L

PF08377 // ENSGT00530000063491_1_Domain_0 (602, 1964)

KAEETTTSTEIK-LSIEADKPTVAESPIKKISSVGEEKDVIKQESEEKKEPCTSNGQ-K
STLFDSELHPKSEE----KTVVPEKKTVPKEGEPQ---KILD--EEMGIVSVSTEKALQK
EEKKDQKSPIDDLRHDSFPEGLEQALSGAATTSKMLDKAPDELGLLSEKSATKELFREEV
VDKDIEAHRTGVAASLDYERQLDEDKSGMSKYFETSTLKEETTKS--IQSGSDYYELSDT
KESVY-ESYDTVSPIHK----SSEKEFYPGKEQKP-APIVEGGYSTLAQSYPAD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIESKEEEE
QLEE------------EK----------V-TGAENIQVESLCESPFLAKDYYKNGSVMAP
DLPEMLDLAGTRSRLASVSADAEVTRRKSVPSETLLEESSTGL-ATLT---DENHVATKA
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYDGSDDKIRRDLATDLSLIEVKLA
AAGRVKEEFSSEGEPS-QPISGDKSGLGREFDHERKSNDKLDTVLEKSEEHIESKEPPKK
VAEGV-------------------DKVEAFG--TGMTFEQVLEK-SPSP----KETFSEK
A-EKSLSSVPEVTEAEPSPKVD-----HGLDAAAQKVEQ---SQLDTKISDFEQAASGLG
VDTEKE---TEPHAQAA--QQDRTHLAKPPEADTFPSIEPSHLKESSKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHDHTPESLAMESLKPDEGKKEVTPEVTVLQEDIAIKLPAE
E-------PPAVD-DSKSYEVKTEGADIQAEQVQEPKEE----VKETPDISITPSEVIEP
-LLQGIVSEPEEAQ--------REGEEEIEARG---EADKLLFRSETLQITDLSVPAVKE
-ELVELGP---SEYKGVIESVVTIEDDFITVVQTTTDEGETGSHSVRFAALEQPEMERRS
SPPEEEE-------------------------EEPQIEEAAEALVEPKEGSPEAPASPEK
G-EVGFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETVPKEEKAEKEVRR-------------------PSLDKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LGKKTEVQAHSPSRKII---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GETNQASGVYKQAK
DKFSDGVSKSPEKRSSLPRPSSILPPR-GVSGDR--DENSFSLNTSMSASVRRTTXXXXX
XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXTPHTPGTPKSGILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVRSKIGSTDNIRYQPKGGQXXXXXXXXX-
------------------------------XXXXXXXXXXXXXXXXXXXGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HIPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLPETS--AH
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGPQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDHPAALPLAAEDTANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFHDQQELDPSPAEPLDKKEKESEKQSKPGEDLKHAALVSQFETTQTSPDEKDI
QDK-KEENVSPSLFGQTLGAGIEDMKQKMEPSLVVPGIDLPAEPP--KVQKDWFIEMPME
AKKDEWGLVAPMSPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFHGGS---FTLPLDV-
------IKNEIV-AEASSFAPVLLQP-SDKKTLEETRGPETAKDS----YKVEEPLKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKTAEVPAAVAIS-ALNEADIPNVED---ISEKASEEEKGDIKQENVQEKETSTLTGQ-V
PTLTEKES----QE----KTTIPEKEAMPKESEPP---KLAD--EETGIIQTSTEHIFSK
EEQEGQEPTAEMLKQDSYPGSLEQPVTDSITTSKILERVSTEPGTLSEKSATQEVFEEKV
ADKDTKVEKVMAATSAEPDMSFYEDKSGMSKYFETSALKEEVTKSIQLQPGSDYYELSDT
SV---HESFDTLAPMQK----NDDKESQAGKESQPSAPAQEAGYSTLAQSHPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSLDEGDD-YLPATTPALEKAPCFPVESKEEEQ
QIEE------------EK----------V-TGEDNIQVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEAARKKSVPSKTVVEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFGAEKETS-PHISDDKLGLGREFDQERKANDKLDTVLEKSEEHADSKEQDKK
TEEA--------G---------D--KVETSG--IGVTYEEELV-KEQTLSKDEAPLMVEK
AE-KALSSVPEVAEVEPSNKAE-----PELDFAAEKVEQ---SELHVKISDFGQMAAGLS
VGPGKT---PELTLEAT-QQDLIPSSKAPVEADMLMGVEPGHIKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPETSPIQDELAIKLSVE
-------IPCTSAISE-ANLATDERADVQMEFIQLPKEG----IKETPDISIMTSDVTEP
-LPEGIVSEPAEA---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGIPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGLHSVRFATLEQPEV-EAR
PSPQDEE--------------------------ELEIEEAAKAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAGGDSTQAPSLFK
QAKDKVSNSTLSKIPALQCSTKSPRCSSACPSLTKRATFSDSFLIQPTSAGSTDRLPYSE
SGNKDGITKSPEKRSSLPRPSSILPPRRGVSGDR--DENTFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITHSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
PHPPEIKDQGGAGEGLVRSANGFPYQEDEEGAFGEHGSQATYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKEQPAALPLXXXXXXXXXXXXXXXX--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------XXXXXXXXXXXL
LTASKMVFPDQKELTPSKTDPLDKQEEEFKKQSKPGEDLQHAALVSQPETAKTSPDAKDV
KDT-EEEKVPLALFGHAVGDSLDDMKQKAEPSIVIPGIGLHAEPSAPKEQKDWFIEMPTE
ARKDEWGLVAPVSPGPLTPMREKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEII-TETVPLTPALLQP-DDKKFLQETSGPATAKDS----AKVEEPHRDEP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DEVAEGQGSEAIT-LPKDTLVNAVEE--SVIVKVSGEEKEASVQETEQIKEIPTPSGQ-E
PTFSGNEIQLKFEK------SIFDKEPIPKDNEPL---KLRD--GETGVMQTSTDHTISK
EEQRGQETSTDALKQEPFPVNLQQAVTDSAVTSKTLENVMTEPTALNEKSVIQELLEEKV
ADKG-KIEGAGAAASAELDLSFYEDKSGMSKYFETSTLKEV-TKS--VQLSSDYYELSDT
RESVC-ESADTVSSTHK----TNDKELQAGKESQPGAPAQEAGYSTLAQTYQPD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEEGK
PSQE------------EK----------A-AREENAPVEISPEPPAVAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADTEVTRRKSVVSETVVEESSPGL-PPVT---DENHVLVKT
DSQLEDMGYCVFNKYTVPLPSPVQDSENLAGDSGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKEEFGVEKEAS-QLVADDKSGPGREFDQERKVNDKLDTVLEKNEEHVDSKEYAKV
AEESD-----------------N--KVETFG--LAVTHEQAPG-KEPAVSKEAPS---EK
A-QKGLSSVPEVAEAEPLKQAE-----PDMDVAAKIDDQ---GQLDVKISDFGQMAAGLK
A--------TEVKLEAS--QAVTPTSKITQEADAFMSVESGHVKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPEEGKKETSPESSLIQDEIALKLSVE
-------IPCPPAVSE-GDLATDERAEVQMEFIQLPKEE----SKETPDISITPSDVTES
-MPDAVVPEPAEA---------PSEEEEIEARG---EYDKLLFRSDTLQIADLGIPGVKE
-ELVETCH---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEM-ERR
PSPHDEE--------------------------ELEVEVAAEAQAGPRDGSPEAPASPER
E-EVALSEYK-TETYDEYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEDKAEKEARXXXXXXXXXXXXXXX----------------------
--XX----------------------XXXXXXXXXXXXXXXXXVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESTQAPSVFKQAK
DKVSDGVSKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSVRRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTENIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDVSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MADERKDDGKAPHWTSAPLTEA-AAH
PHPPEMK--D---------------------QGG-----AGEGLSRSANGFP----YREE
E-EGAFGEHGSQGAYSDTKE-NGINGELTSADRETAEEV-SARIVQVVTAEAV-------
---------AVLKGEQEKEAQHKDQPAALPLAAEETVHLPPSPPPSPASEQTVAVEE---
------------------------------------------------------------
----------------------------------------------AAG-----------
----------------------------------------------GESAQAPSALKQAK
DKVTDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILSKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDDAKAPHWTSAQLTEAS--AH
PHSPEIKDQGGAGEGFVRSANGFPFREDEEGTFGEHGSQSTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSP--
ASERTVAVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTAPKMEFHDQQELTASLPEPLDKKEKELENQSKPGEDLKHAALVSQPETTEMSSDKKDR
RGP-EEGRVPLTLFGHTLGAGLEDSKQKAEPSLVVPGIDLPPETPVPKEQKDWFIELPME
TKKDEWGLVAPISPGPLTPMRKNDVFEDIPKWEGKQFDSPMPSPFHSGS---FTLPSDV-
------MKNEIV-EEASSFAPALLKS-DDKTSLEETSGPVTAKDT----SKVEEPHKDKP
Y

PF08377 // ENSGT00530000063491_1_Domain_0 (602, 1964)

KMAEVPASEAIP-SPKEAHILDVEE--CVPEKVLEEEKGAIKQESVQKKEMPTLSGQ-E
SSLTEKESQLKLEE----KTTIPDKETMLKESEAP---KPKD--KETGVIQPSTEHTFSK
EEQKSQQPT--TLKQESFPESLEQAVTSSAMASKALEK---EPAVLSEKNAIEDLFEEKV
ADKGNRVEGVGAATLAELDMPFYEDKSGMSKYFETSALKEEVTKS--FQPGSDYYELSDT
RESAQ-EPFDTVSPMHQ----YGDKGLQAGKEPQPGAPAQEAGYSTLAKSYPPD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFSRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPCFPIESKEEEE
QIQG------------EK----------A-AGEGNTQVETVCESPFLAQDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADTEVGRRKSVPSGNVIEENRTGL-PPVT---DENHVIVKT
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDVATDLSLVEVKLA
AAGRVRDEFSAEKEA------SPQSGLSREFDQERKANDKLDTVLEKSEEHTDSKEHARE
SE--------EAG---------D--KVETFG--LGITYEHALA-KELTVSKDASSAMAE-
---KGLSSVPEVAEAEQSKKAG-----SELDFVAKKAEQ---GHLDVKISEFGQMASGLN
IDAAKS---TEPKFEAT--QDLTLLSGTPQEAGVFMGVESGHMREGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPEEGKKETSPESSLIQDEIAIKLSVE
-------VPCAPAVSE-AELAEDERADVQLESIQPPKEE----SKETPGISITPSDVTEP
-LLEAVGAEPAEA---------QNEEEEIEARG---EYDKLLFRSDTLQITDVGVPSVRE
-EFVEACP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHAEE--------------------------ELEVEEAAEAQAEPKDGAPKAPASPER
E-VAGLSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIMKEA-----------
----------------------RR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESYQVPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRAVSGDR--DENSFSLNSSFSSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILSKKMDF
SKVQSRCGSKDNIQHSAGGGNIQIVTKKIDVSHVTSKCGSLKNIRHRPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HMPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSNL
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
-----EVSARIVQVVTAEAVAVLKGEQEKEAQHKGPPAALPLAAEETANLPPSPPPSP--
ASEQTVAVD---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMESHDQHELSPSTTEPLDTKAKEAEKQSKPGEDPKHAALVSQPETTGTSPGGKDG
QEQEEEDRAPPSLCGHTLDAAPEDFQQKTDLSSPVPGIGFFAESPTQKEQKDWFINMPTE
AKRDEWGLAAPISPGPLTPMKVKAHAEDLPKWEGKQFDLPXXXXXXXXX---XXXXXXXX
XXXXXXXXXXXX-XX-------XXXX-XXXXXXXXXXXXXXXXXX----XXXXXXXKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 2020)

DKLAETLASVAIP-SPEDTHILVEER---TTENVPEEEREATIEASGQKRGPSTSSGD-K
PILPETEPQLQHEE----KSTIAAKEALPEDSRPP---QLTG--DATGILQTTTEQTSPK
EAQKGLEPTTDSLQQDLAPLTSEQSVTDSAMAARALEEALTEPCTLSAKGSIQELFDERV
IDNDGKIESAGAAASSELDMPFYEDKSGMSTYFETSALKEEVTKS--IQPGSDYYELSDT
RESSH-ESFDTLSPLHK----SEDKGAPAGQEPQPRVAAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YFPATTPALEKAPCFPIESKEEEE
QIEE------------EK----------A-TGEETIQAETSCESPFRTKDYDKNGTVMTP
DLPEMLDLAGTRSRLASVSADAEMARRKSVPSETVMEESCTGL-PPVTMSPREHHVVVKT
DSQLEDLGYCVFNKYTAPLPSPVQDSENLSGESGSFYEGTDDKARRDLATDLSLIEVKLA
AAGRDQDELSGEKESS-PPT----SGPGREFDQERKANDKLDTVPEKGEEHVDAKEHTQE
AE--------EAG---------D--KVETFD--LGVTGEQSLA-EELTGSQDTPPLMAEK
GE-GGLSSVLEVAEGEPAKKMN-----Q--DRAAEKAEQ---GPLEVXXXXXXXXXXXXX
XXXXXX---XXXXXXXX--XXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX-XXXX
XXXXXXXXXXX-XXXXXXXXXX----XXXXXXXXX--X---XX-XXXXXXXXXXXXXXXX
-------XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX----X----XXXXXXXXXXXX
-XXXXXXXXXXXX---------XXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX
XXXXXXX--------------------------XXXXXXXXXXXXXXXXXXX----XXXX
X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------
---------XXXXXXX---XXXXXXXXXXX-------------XXXXXXXXXXXXXX---
--XX----------------------XXXXX---------------XXXXXXXXXXXXXX
XX--XXXXXXXXXXXXX---XXXXXXXX--XXXX--XXXXXXXXXXXXXXXXX-XX-XXX
---------XXX-X--------------XXXXXX--XXX

ENSGT00530000063491_1_Linker_0_2 (2020, 2179)

XXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXSEPI
R-RAGNSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSGILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTENIKYQPKGGQVRILNKKIDL
SKVQSRCGSKDNITHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNIK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

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------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SDIQSRCGSRDNIKHSAGGGNVSSMDTLAGLSHRVSLCGCDKKITLKDGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSM
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLAEAS--AH
PHPPEIKDQAGAGEGLVRSANGFPYREDEEAAYGDHGAQGPYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPTGLPLAAEETANLPPSPPPSP--
ASELTVPLEEGKSCWT--------------------------------------------
------------------------------------------------------------
-----------------------------------------L-QELSPEVKTPSS-----
--------------------------SKEGLESEPGEDLKHAALVPQPDATQTSPKSKGT
QGA-EGEKAPSSLFGQPVGATLEDMKPKAEPSFIVPGIGLPAQPPASKEQKDWFIEMPVE
TKKDEWGLAAPVSPGPLTPMREKDVLEDVPRWEGKQFDSPMPSPFQAGC---FTLPVDI-
------MKNEII-AEASPFDPLSLQPD--DKHTPQEIGPVTAKDS----AKVEDTQKAKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVAEAAAPEAIT-LPTDAHVPVVEE--SVTEKGLGEETGVTPQE---KTEISTLSGQ-E
LALAGRELQPKLEE----KTSISDKEAVPKEHEPS---KLRD--EETGIIQTATEHTYLQ
EEPKSQEHATDMLKQDSFPASLEQAMTDSTMTSNTLEKVSIEPAALHEKSTLQELFQEKV
ADKDSKVEGVGAAQSTEIDMPFYEDKSGMSKYFETSALKEEVTKS--IQLASDYYELSDT
RESAP-ESVESISTMRE----DGDKGSQAEKEPQPSAPAQEAGYSTLAQSYPAE----VP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVEKAPCFPIESKEEEE
KLEE------------EK----------T-TGGENTQVEAPCESPFVAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEAARRKSVPSETVIEESSTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGDSGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFGAEKETS------PTSGLLREFDQERKGNDKLDTVLEKSEEHADAKEHAKE
AQEAGA-------------------AVDMFG--LGVTHTEPSA-KELTASKDAAS---EK
A-EKGLSSVPEVAEVEPSKKTE-----HELDFA---------APLDVKISDLGPIMARLD
VDAREI---AELTLEVQ--QEQVPPSEAPREADVFLGVEAGHLKDGARVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEIALKVSVE
-------VPCPPAVSE-ADLAAQEPADVQMESIPTLPKE---DSRETPDIAVTASDVPEP
Q-PEAAMAPPAEV---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGAPSSRE
-NVLETCP---GERKGGIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEM-ERR
PSPQEEE--------------------------ELEEEVAAEAQAEPKDGSPEAPASPER
E--AALSEYK-TETYDDYKDETTIDDSVMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKADKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKK-------
-----EVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTATG-----------
----------------------------------------------GESTQAPSVFKQAK
DKVSDGMTKSPEKRSALPRPSSILPPRRGVSGDR--DENPFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSFPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2267)

-QIVTKKIDVSHVTSKCGSLKNIRHRKQLN------VK-
-------CSLAKWEQCHWHQPGGP----IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDDAKAPHWTSAQLTEAS--AH
PHPPEIKDQAGAGEGLVRSANGFPYREDEEGTFGEHGSQSTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVVKGEQEKEAQHKDQPEALPLAAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFHDQQELTASLAEPLDKKEKESEEPSKPGEDLKHAALVSQPETSKTFPDKKDM
QGT-EEGRAPLTLFGHTLGAGLEETKQKTESGLVVPGIGLPEETPAPKEQKDWFIEMPME
AKKDEWGLVAPISPGPLTPMKKKDVFEDIPKWEGKQFDSPMPSPFQAGS---FTLPVDV-
------MKNEIV-AEASPFAPTLLQP-DDKKSLEETGGPVTAKDI----SKVEEPHKDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPALEVVT-SPKVAHI--MEE--CVPEKVLGEDK-AMKQESVQEKEMSILSGQ-E
SILTEKEPHLLEE-----KTTIFDKETMPKDSEPS---KPMD--KETGVIQPSTEHTLPK
-EQEGQEPTTSTLKQEPFPVSLEHAVTNLAMTSKTLEKVMNEPAALSEKSAIEDLFEEKI
ADKDSKVEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
RESAQ-ESFDTVSPMFK----NGDKGLQAGKESQPSAPAQEAGYSSLAKSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIESKEEEE
QTEG------------EK----------A-TREGNAQVETSCESPFLAKEYYKNGSVMAP
DLPEMLDLAGTRSRLASVSADVEVARRKSVPSETVVEESTTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSRESGSFYERPDDKVRRDLATDLSLIEVKLA
AAGV--DEFSAEEAA--PPVSGD-SVLGREXXXXXXXXXXXXXXXXXXXXXXXXX-----
--------------XXXXXXXXXXXXXXXFG--LGITYDHALA-KELTISKDASS---EK
T-EKGLSSVPEVAEVEPSKKAE-----PELDFAAKKTDQ---SHLDIKISDFGQMASGLI
-DAGKA---TELKLEAI--QDLAPLSAAPQEADALMGTESGHMKEATKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTIESLKPDEGKKETSPESSLIQDDIAIKLSVE
-------IPCAPAVSE-ADLAPDERADVQMESIQLPKEE----SKETPDISITPSDIVEP
-LLKAVGAEPAEA---------QSEEEEIEARG---EYDKLLFRSDTLQITDLGVPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGELGSHSVRFAALEQPEV-ERR
PSPQVEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVALSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEVRR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTAAG-----------
----------------------------------------------GESTQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSIASAARRTTXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPSE
KKVAIIRT--KSPALPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPD-KNVKSKIGSTDNIKYQ-KGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSSQLAEAS--SH
SHPPEIKEQSSTSEGLVRSANGFPYREDEDGGYGARGQQSSYSRTKENGINGEVATGEKE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAPLPLGKEYNCNCPPPPPPPS--
ASVI--------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------SSQTTADL
FAASKMEIHVQEGTDLFAAEPLGMKD--SEKGSKTSEQSLHDALVLQPAKTESIQR---A
ESPDEEEKTPPTLLEQTLDANHQKQELRG---SVKTDIDSTRDSDQHQEQKDLSTQWHQE
GQTDEIATTSQKSTSKALPTESKDYQTDLKRY-----DFPSP--GSIGSSSLSELTMDTR
STV----KTI-FSSDTLPGAHHKSGSVETNKRIH----ISTASDIAKDLMKDHKMDKEKI
KKQEEDFAIATIPSLP-----PVT

PF08377 // ENSGT00530000063491_1_Domain_0 (625, 1964)

EETSVQNVPLWEEEKDMTEDESDEEGY-SVSSRQKH
RALDDQSF-------------------VACADQPT-----------KGAIG----KEAEK
EGKHSMETFADRFSQELFPEKVEASLNRHALSE--MESPSTEP--------SDETLHRKD
SGKNCKDAEFSVGDSVTHKVQVEEDKSGMSTYFETSALKDESVKSDILLHGSDYYELSDT
KEQTY-DPYHKDFLFAK----KDTEEYQPDSYQLPSIPTHEIGYSTLAQSFPED----EP
REPSSPKERIYTIDPNVYGDKRELHNKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRTHDLSPLGSDILDNASG--DEGDD-YLPVTTPAVEKTPTFPTDSREEEE
EVVVVEEEEDEKEKIEEP----------IMKEEGEIQVEPSCESPFLAKDYYKNGNVMAP
DLPEMLDLAGTRSRLASASTEAEGAQSKSILSEGPEEDSSTTQ-HLMK---DENHMTLKA
DSQLEDLGYCVFNKYTVPMPSPVQDSENLTGESCPFD----EKIRRGVITDLSLIEVKLA
AAERSKEEKE---------ASSDSVLLGKDFEQERKAIDKLDTVLEKSEEPTDSKEAYSS
EDAEHTRVKPDSTLETVDDKSLA-------G------------------VEEKVSLITQK
EE--DDIHITKTGTPEISCKPDYDAIKHDLDSAALQVEQEYQSKLGVHPDESVSGQSTVD
R-------------------DK-IPSVLPEEPIVCAKLEPCPIKDATKLSEIEFKEKGAK
PDLVHQEAVDKEESYESSGDNDQAQEGLPGDTSKPYVGKIEP--ESPSLSEETVSQVLVE
Q---------QVVETEVSKATPEEAAEIQMENIPQSKTDQVESLELA-D-SVKTEDLVHH
LEYEKKDVEGEQQK----EVKQPEEHKEVKQA----------------EELKEDIKEAEE
YEETQAIPGELPELKGVIESVVTIEDDFITIVQTTVDEGDASSHSVRFAETQQADIEEEG
IHPEEE----------------------------VDMEVVADIKEEKKDTSLEAPGSPER
E-EVPLTDYK-TETYDDYKDETTIDDSILDTDSIWVDTQDDDRSIM---TEQL-------
---------ETVPKEEKAERELRR-------------------PSLDKHKKEKALKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKAVYKKAE
LSKKAEVQAHSPSRKII---LKPAI-KH--TRPT--HHSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KQTAAA-----------
----------------------------------------------GETNQTPGMFKQAK
EKLSDGIIKSPEKRSSLPRPSSILPTRRGISADRERDENSSSLNSTIS-SARRTTRSEPI
RSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPRSAILVPTE
KKVAIIRTPPKSPGTPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVRSKIGSTDNIKYQPKGGQI---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2304)

VKIESVKL
DFKEKAHAKVGSLENAH-HVPGGGHIK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MAEDRKDE--------AKAPHWTSGQLTEAASH---PHSP-------
----------DIKEQGGAG------------------------AGLVRSANGFPYQE---
--GEEPGLGSREQPGTYARSKENGINGELSAGDRETAEEVSARIVQVVTAEAVAVLK-GE
QEKEAQ-HKDQPGPLPI--AVEESA-NLPPSPPPSPASEQTGALEEAAV-----------
----------------------------------------------GETNQTPGVFKQAK
EKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPI
RSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQL

PF00418 // ENSGT00530000063491_1_Domain_2 (2180, 2210)

RVINQPLPDLKNVRSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2241)

VRILNKKIDF
SDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDDGKAPHWTSAPLTEAA--AH
PHPPEMKDQGGAGEGLSRSANGFPYREEEEGAFGEHGSQGAYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETVHLPPSPPPSP--
ASEQTVAVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPEQQKLTS-LDEPLDKGEKEMEMQSKPGEDFEHAALVPQPETTKTPQDKKDL
QGT-EGEKSPSIPLGHTFGTNLEDIKQNTEPSITVPSIGLSTEPLALKEQKDWFIEMPME
PKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FTLPLDT-
------VKDETVTEAPQPLAPVFFQP-DDKTSLQDTSGLATAKDS----CRVEEPQKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DNMGDVPVSDVAT-LPKDAHSPVMEG--YAAGGVSGEEKGATNQE---KKETPTSGGQ-E
PTLTENEPQTKLEE----KLVVPIEEAVAKEHEPP---KLRD--DEIGALQTSTEHFFSK
EEQKGQEQVADELKQDSFPVSLEPALSDSAMTSGALGKVTSESEAVCEMRETRGLFEENI
GIKD-KFEGVGSTTIAEVGMPFYEDKSGMSKYFETSALKEEVTKS--EQLGSDYYELSDA
RGSAQ-ESLDTVSPKHQ----LGEKELQA-KESQPSAPAQEMGYSTLAQRYPSD---ELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKVPCFPIESKEEEE
KAEE------------AK----------V-TGEQTIQIETSSESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSAEAEVARRKSVPSEAVVAESSTGL-PPVA---DENQVAVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDELTAENEPS-APTSADKSGLSRELDHDRKANDKLDTVLEKGEEHVESKEHAKE
TA--------EAG---------E--KVDLFG--LGVTYEQAST-KELTTAEDTSP---EK
AA-KGLFSVPEVAEVEPTPKAD-----QGLDFAAKKAEP---SQLDIKVSDYGQMASGMN
VDAGKA---TELKFEVS--PELALSSKEPQEEDSFMVVESGHMKEGAKVNETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKPDEGKKETSPESSLIQDEVALKLSVE
-------IPCPPPVSE-ADLSTDEKAEVQMEFIQLPKEE----STETPDIPAIPSDVSQP
-QPEAIVSEPADVP----------SEEEIEAGG---EYDKLLFRSDTLQITDLVVPGSRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALAQPEE-ERR
PCPHDEE---------------------------LEVEMAAEAQAEPKDGSPDAPATPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAG-----------
----------------------------------------------GESAQAPSALKQAK
DKVTDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MAEDRKDEAKAPHWTSGQLTEAS--SH
PHSPEIKEQGGAGAGLVRSANGFPYQEDEEHGLGGREQPGPYAQTKENGINGELSAGDRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKEQPGPLPIAVEESANLPPSPPPSP--
ASEQTGALE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LAATKMEFRVQEGTCPFTTEPLDTKRQESGKDSKT-EQPKHDALVPQPAKTE---DKKDS
QSK-DKEKMPSHPTEQISET---DSQKKGEVSFAEPASKL----PGFQEQKDLPSELPKG
SKTEERTADVPSSSNQIMSMTFKDDLKDVQDLAISH----------EGSSLMLSEPKA--
----EAAKSELP-SGPSPAVPQELSLKDSSKTKQEPTDHLFAK

PF08377 // ENSGT00530000063491_1_Domain_0 (584, 1964)

DL----AKDEQIHRDMT
LALHE--EVA----------VDGLKTPSAQKIPAWGEEKDMTREESDEEERYDFYDKGEA
RILDDGKFATKPEV----KALSQDKADFQKDAEAKMSSDLFKAEKEMDQSGLPATV----
-----------DLKKDVQPSTEVSPGKL--SPELTLEKT-AEHPDTTQLSRTTEKTPEKD
VKKDTKDD--KTSVSATPEMKAEVDRSGMSKYFETSALKEEAFKADALKQGSDYYELSDT
KESAY-EPYQTGRLIPEDKE-EEEEELQTELGQQQGMPAHEIGYSSLAQSYTPD----KS
EEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPIDSREEDE
HIEE------------EK----------A-MAEEKVQPETSVESPFPAKDYYKNGAVLAP
DLPEMLDLAGTRSRVASVSADAEVAQKKSVPSDTVLEDSSAAL-PPVT---DENHVTLKA
ESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRSLAPDLSLIEVKLA
AAEKSKEEFLSEKDL---HA-AGESVLGRDFEQEK--KEKLDTVLEKSEDQVDSKEEMKE
ESVADK-----------------------VHVPADTAYDRMLS-AEATAEKDAVSFLME-
E--KTLSVVPEMAEIEAPVKPDYNAIKHDLEVAAMRADQEYQSQLESKISE-GSLPSGKD
KAPVKR---AGPEPKETQQKDQTILSREAKDADVLSKTEPSYVKDSTKLSEIEIKEKVAK
PDLVHQEAVDKEESYESSGEHDQAQEGLNGEPLKQEDIKGEP-PKPTVCGEEVPAQLPAK
-------EPSMELLLPKTEPPQEEPAEIQMESIPQPTEE----TEKIPDTAVKPTEIQTV
LPSEVTAG-AARR-------------------------EEQHLTPEMPQEMDLGKPTSEE
-MLAKVCPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIETVD
SQAEE----------------------------ELEVEEVADIHAEPKEGSPEAPASPER
E-EILLTDYK-TETCEDYKDETTIDDSIMDTDSLWADTQDDDRSIM---TEQL-------
---------ETVPKEEKADRELRR-------------------PSLDKHKKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSR-KI--ILKPAI-KYTR----PTHLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KQTAAG-----------
----------------------------------------------GETNQAPGVFKQAK
EKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTASLSSSVRRTTRSEPI
RSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVRILNKKIDF
SDIQSRCGSRDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2272)

VQIVTKKIDLSHVTSKCGSLKNIHHKPGGG

ENSGT00530000063491_1_Linker_4_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLENAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEGKAPHWTSASLTEAA--AH
PHSPEMKDQGGAGEGLSRSANGFPYREEEEGAFGEHRSQGTYSDTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQQKDQPTALPLAAEETANLPPSPPPSP--
ASEQTAAVG---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFPEQQKFPSSFAEPLDKGEMEFKMPSKPGEDFEHAALVP--DTSKKPQDKNDL
QGM-EGEKLPPAPLVQTFGTNLEDRKQSTGPSIAMPSIGLPAEPPAPKEPKDWFIEMPTE
SKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGS---FTLPLDT-
------MKNERVSEGPRPFAPVFFQS-DDRVSLQDSSALATAKES----SKDEEPQKDKA

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKVADVPISEVTT-LLGNVHCPVVEG--YVGENISGEEKGTMDQE---KKETSAPSVQ-E
PTLAETEPQTKLEE----KSTVSIEEAVAKEEESL---KLSD--DKTGVIQTSTEQSFSK
EDQKGQGHTIDELKQDSFPVSLEQAVTDAAMTSKTLGEVTSEPEAVSESRETQGLFEEKA
ADKN-KLEGAGSATIAEVEMPFYEDKSGMSKYFETSASKEDMTRS--AELGSDYYELSDS
RGSAQ-ESLDTVSPKNQ----HDEKELQ-AKASEPSPPAQEAGYSTLAQSYTPDHPSELP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPPTTPAVEKIPCFPIESKEEED
KAEQ------------AK----------V-TGGQTTQVETSPESPFPAKEYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSEAVVAESSTSL-PPVA---DESPVAVKP
DSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFTAEKEAT-PPTSADKSGPSREFDHDRKANDKLDTVLEKSEEHIDSKEHVKE
SEEIGD-------------------KVELFG--LGITYDQAST-KELITTKEPSP---EK
T-EKGLSSVPEVAEVEPTTKAD-----QGLDFAAKKAEP---SQLDIKVSDFGQMASGMN
VDAGKA---IELKFEVA--QELTLSSEAPQEADSFMGVESGPTKEGVKVNETEVKEKVTK
PDLVHQEAVDKEESYESSGEHE----SLAMESLKPDESKKETSPETSLIQDEVALKLSVE
-------IPCPPPVSE-ADSSTDEKGEVQMEFIQLPKEE----STEAPDIPAIPSDDTQP
-QPEATVSEPAEV---------PSEEEEIEAGG---EYDKLLFRSDTLQISDLLVPGSRE
-EFVETCP---GEHKGVVESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEE-ERR
PCPHDEE---------------------------LEVEMAAEAQAEPKDGSPDAPATPEK
E-EVAYSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIL---TEQL-------
---------ETIPKEERAEKEARR-------------------PSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKSEVQAHSPSRKLI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAS-----------
----------------------------------------------GELAQAPSAFKQAK
DKVTDGITKSPEKRSSLPRPSSILPPRRGVSGDR--EENSFSLNSSIS-SARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRT---PGTPKSGILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQV---------
---------------------

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

-QIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPSRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--EH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKNDM
QGT-EEEKAPPALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKALQQTSGPATAKDG----FKIEEPHEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSETMT-LPKDAHILVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PTLTEKELEPKLEE----KTTISDKEAVPKESKPP---KPAD--EDTGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKS--IEPGSDYYELSDT
RESVH-ESIDTMSLVHK----NGDKEFQTGKEPQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESPFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVIEKSEEHADSKEHAKK
TE--------EAG---------D--EVETFG--LGLTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSIAPQEVDAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVS-----------------------------------------------------
----DGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2271)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_3_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADERKDEAKAPHWTSAQLTEAS--AH
SHPPEIKDQGGAGEGLVRSANGFPYREDEEGTFGEHGSQGTYSNTKENGINGELTSADRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSP--
ASEQTVTVEEE-------------------------------------------------
--------------------------------EETLESRMAEEEKPAALPERECGA----
AKSSDQPKGLSKGQMESSAETQIVPEESAPAGAPHEKSVKEV-KEVSPEVKNPSSAGEDL
LTASKMEFHDQQELTPSAAEPLDTKEEESEKQSKPGEDLKHAALVSQPETTKTYPDKKDM
QGT-EEEKAPPALFGHTLVASLEDMRQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTE
AKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGS---FTLPLDV-
------MKNEIV-TDTSPFTPAFLQP-DDKKSLQQTSGPATAKDG----FKIEEPHEDKP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKMAEAPPSEAMT-LPKDAHIPVVEE--HVTGKVLEEEKEAINQETVQQKDTFTPSGQ-E
PILTEKELEPKLEE----KTTISDKEAVPKESKPP---KPAD--EEAGIIQTSTEHIFS-
-EQKDQEPTTDMSKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRV
DDKD-KIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEAIKS--IEPGSDYYELSDT
RESVH-ESIDTMSLVHK----NGDKEFQTGKEPQPSPPAQEAGYSTLAQSYPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPALEKAPCFPVESKEE-E
QIEK------------VK----------A-TGEESTQVETSCESRFLAKDFYKNGTVMAP
DLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGL-PPVT---DENHVIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLA
AAGRVKDEFSVDKEAS-AHISGDKSGLSKEFDQEKKANDRLDTVIEKSEEHAHSKEHAKK
TE--------EAG---------E--EVETFG--LGVTYEQALA-KDLSIPTDASS---EK
AE-KGLSSVPEVAEVESSKKVE-----QGLDFAV-------QGQLDVKISDFGQMASGLN
IDDRRT---TELKLEAT--QDMTPSSKAPQEVDAFMGVESGHMKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAVKLSVE
-------IPCPPAVSE-ADLATDERADVQMEFIQGPKEE----SKETPDISITPSDVAEP
-LHEAIISEPAEI---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGVSGARE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHDEE--------------------------EFEVEEAAEAQAEPKDGSPEAPASPER
E-EVAFSEYK-TETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAE
LAKKTEVQAHSPSRKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2183)

KTTAAGGESALAPSVFK
QAKDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLMQPTSAGSTDRLPYSK
SGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISSSARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQLRLI

PF00418 // ENSGT00530000063491_1_Domain_2 (2183, 2210)

NQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDF
SKVQSRCGSKDNIKHSAGGGN

PF00418 // ENSGT00530000063491_1_Domain_4 (2242, 2271)

VQIVTKKIDLSHVTSKCGSLKNIRHRPGG

ENSGT00530000063491_1_Linker_4_5 (2271, 2273)

GR

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL

---------------------------------MADDRKDEAKAPHWTSAQLTEAS--AQ
PHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSTDRE
TA--EEVSARIVQVVTAEAVAVLKGEQEKEAQPKDQPPALPLAAEETANLPPSPPPSP--
ASEQTVPVE---------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------EGL
LTASKMEFHDQQELTPSPAEPLDKKEKEPETESKPGEDLKHAALVSELETTKTSPDKKDI
QGT-EEEKAPPTLFGHTLGASLEDTKPKTEPSLVVPDIGLPAEPTAAKEQKDWFIQMPTE
AKKDEWGLVAPVSPGPLTPMKEKDVLEDIPKWEGKQFDSPMPSPFQGGS---FTLPFDI-
------SKHEIV-AAAASFAPALLQP-DDQKSLEETGSPATAKDS----SKVEEPQKDQP

PF08377 // ENSGT00530000063491_1_Domain_0 (601, 1964)

DKIAEAPASEAVA-APKDAHVSIVEE--CVPEKVSGEEKGMIKEESVQIKETPTLSEQ-E
STLAEKEPHLKLEE----KPTISDKEAMPKESEPP---KLID--EETNIIQPSTEHTYSK
KEEKGQEPPTDILKQDSFPVSLEQAVTDSAMTTQTLEKVMTEPTALSEKIATQELFEEKV
ADKDHKVEGVGVVTSAELDMPFYEDKSGMSKYFETSALKEEVTKS--IQPGSDYYELSDT
RESVQ-EAFDTVSPMHK----DGDKALP-EEEPQPSAPAQEAGYSTLAQSHPSD----LP
EEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCL
DSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDD-YLPATTPAVDKAPCFPTESKEEKE
QAKE------------EK----------D-TGEENARVETSCESPFLAKDYYKNGTVMAP
DLPEMLDLAGTRSRLASVSADTDVARRKSVPSETVVEESSTGL-PPVT---DENHIIVKT
DSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKARRDLATDLSLIEVKLA
AAGRVKDEVSAEKEAS-PPISGDKSGLSREFDQEKKASDKLDTVLEKSEEHADSKEHAKE
TE--------EAG---------D--EVETLG--LGVTQEQASA-RELTVAKDASPVMAEK
AE-KGLSSVPEVAEVEPSKKAE-----PELDLAVKKAEQ---GQLDIKISDFGQMASGLH
VDAGEA---AELKLEAT--QDLAPSSTAPPEVDAFMGVESSHLKEGTKVSETEVKEKVAK
PDLVHQEAVDKEESYESSGEHE----SLTMESLKADEGKKETSPESSLIQDEIAIKLSVE
-------IPCAPVVSE-ADVAADERADVQMEFIQPPKEE----SQETPDISITPSDVTEP
-LPEAARAEPAEA---------QSEEEEIEAQG---EYDKLLFRSDTLQITDLGAPGVRE
-EFVETCP---GEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEV-ERR
PSPHAEE--------------------------ELEVEEAAEAQAEPKDGSPEAPASPER
E-EVGLSEYK-TETYEDYKDETTIDDSIMDADSLWVDTQDDDRSIM---TEQL-------
---------ETIPKEEKAEKEARR-------------------SSLEKHRKEKPFKT---
--GR----------------------GRISTPERKIAKKEPSTVSRDEVRRKKGSFHNHF
FMNVFE-VIHYYSFKFI---LKPAI-KY--TRPT--HLSCVKR

ENSGT00530000063491_1_Linker_0_2 (1964, 2179)

KTTA-AG----------
----------------------------------------------AESAQAPSVFKQAK
DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDR--DENSFSLNSSISS-ARRTTRSEPI
R-RAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE
KKVAIIRTPPKSPATPKQ

PF00418 // ENSGT00530000063491_1_Domain_2 (2179, 2210)

LRLINQPLPDLKNVKSKIGSTDNIKYQPKGG

ENSGT00530000063491_1_Linker_2_3 (2210, 2211)

Q

PF00418 // ENSGT00530000063491_1_Domain_3 (2211, 2272)

VQ--------
-----------------------IVTKKIDLSHVTSKCGSLKNIRHRPGGG

ENSGT00530000063491_1_Linker_3_5 (2272, 2273)

R

PF00418 // ENSGT00530000063491_1_Domain_5 (2273, 2305)

VKIESVKL
DFKEKAQAKVGSLDNAH-HVPGGGNVK-IDSQKLNFREHAKARVDHGAEIITQSPGRSSV
ASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL