Query Results 

---------MSQMANV-NLC--------ASGKSGSVLNGDSDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPAPPSAGP-KDP---QGQFGVWASTES-LSSSNS
DDT-KHCPSFLSARSQAAA--SPAARQPPAPPDASASFLAIPENKQLPPSSPQLPRHNLH
VTKTLMETRRRLEQEKVIMQVAP--GEYRRPRLASFGGLGSTGSLPSFLGSGNHN-PAAH
PLQNGYPGNGDCGLYSAA-AAASSLGSSLRHSPMSSGISTPVTNVSPLHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKSQRPASQSDAGGLRPRSYSAGNAG
QLQQLSRVRG-GGGGELYIDCEEEE-MESVEQSAQRIKEFRQLTAEMQALEKKIQDSSYE
AP-PEPRENG-EPPARGRRSVAVGADRVEE-------GAVARKEAAVGTETRTRDCGVGV
TEAMLGVTTEADKEIEFQQQTIEALKEKIYRLEVQLKETTYDREMTKLKQELRAAGSRKK
VDKGCMAQPRVLHRMVEAVVQTRDQTAGPHVAVADACVGTSLQTCSRGVSCRPGGDHKLV
GPELPMSRWVVKERAETRDQCVGRSAETRDKA--VETSVCAAGGHTDASP-----REAQP
-EVRGVRSVACGDCSVLVTVCSPAERHSQGVNTEPPCLADSSVMAAPQTVSRHTATVLEQ
ADQFTNTEAPPLADCGTNTSLSTLDKQTNTRTVDVRTVAVGEGRVKDVAASSKTRSVGVG
TLLSSDAALDKPSAVKTKDAGVGQISIHENYLVGLKLRNMACGPPP---LTVGSAASRRS
VGVGDEPVGDLV-GPP-PSQ-APELMTGLDHYIELVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKYTSPEELRNTDVQRQNLDK--TAGHNLECIS--NSH
V-T-SSDVT-SNAEITM----------HEQEDGTR-KGAKVTMIGVSPDQESFPSQ-DNT
SPVNLTDDQIAAG--LYVCA-NSDGTLKSIMKK-DGKKESNS--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVLEEE------------LVEENTQGMAEGQHAVNVESF
RSVSVE-NEIKVQESKPEKVEIRERYELNEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTIQHEWFRVSSQKAAIPAMVGDYIAAFEEVSPEVLQYI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGTLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKPQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTNR-TGR--------APGKAGSVLNGDHDTDQRDPYSVETPYGYQLD
LDFLKYVDDIQKGHTVRKVTIQKRHKPSAPCLEA-RAA---PSQPGG-TSTES-LSTS-S
SDS-RHCRSFLPDSSHATS--TPVPR-LPTPLEPTPASLAVPDSRHAPPASPQLPRHNLH
VTRTLMETRRRQERGALQXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXX
XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX
XXXXXXXXXX--XXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XX-XXXXX---XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQAASSREE
GDKATMAQPLVCSRMAEAVVPTRDQTVGNHVDVA-DCVGSAVETRSTGVSCRPDTHSISV
GPEQPMDRWVVRERVDVRNQCTGRSTEMCSKAVDVRISVCETGSNTEESVSDLCLLQTHL
-SLPDVRSVGCGDCSVDVDVSPQKACVSRGVNTEAVGLAEAAVLAVPLTASQHTSTAWAQ
EERSTNTEAATLVESGTNTCLSTSDKQTSTGTVATRTVAVGEGRVRDVGAPPKTRSVGVG
TWLSGHAGFDKPSAVKTRDAGVGQVSIHDHYLVGLRMRSIACGPHQ---VTPGLTGSRRX
XXXXXXXX---XXSLMAPQQAPPGLVTGLDLYIERVKRLLYEQQMMFTDNSIELTVSFVE
PASQMGSLNSQLLSTLSSISSVMESARSEELRGTSYQKVSLGKARQAP------------
--LLEEAGVE-----------------TE-----ATEG-----MPNGDGQGDFVPPESSL
CPVNLTDDQIAAG--LYAHAAAGEATLKSIMKTRGGSRAGSGAGAKKNLQFVGINGGYET
TSSDESSSEESSS-SESG-EADGPAYPPEEEED--------DEDPRA--------VAEGL
RSARVA-AEMQVQESEFEKVEIRERYELSEKILSACHLLKTNLKDPRALASKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFQAVSPDVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFQIVKLLLDADVCNVN

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

RQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEEDM
RVVGELFACGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVRGLLACGADVNTQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHAEIVKLLLAQPGCHGHLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1427)

DGSTALSIA-EAGHKDIAVLLYAHVNFAKAQSPS
TPRLGRKMSPSPTHRASFD-

---------MAHTTNI-SGC--------ASG-KADVLNGDHDKGQKDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRQKPSVPYPET-RVT---PGQQGIWTSTES-LSSSNS
DD--KQCPNFLLARSHITS--TPIPR-PPAPLEASPTFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQEKATMQVSP--GEFRRPRLASFGGMSSTSSLPSFMGSGGHN-PAVH
QLQNGYQSNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLSSQLKNQRAASQSDVYGVRKRSYSAGNAS
QLEQLSQARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSNYE
VS-SELRENG-ECRPRECRSVAVGADENMNNIVVYHRGSRSCKDAAVGTVTETKNSGVIV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAIMAQPLVFSKMVEAVVQTRDQMVGSHVDMVDMCVGTCVQTNSIGISCQPDFMNKVV
GPELPMNWWIVKERVEMHDRCTGRSMETCDKSVGVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTICFPKEYTSRSMNTEALGRAEAAVMAVPLTTSQHTNTVLEQ
AHQFTNTETVTLLESSTNTFLSTLDKQTSTQTVEMRTVAVGEGRVKDINSSTKTRSVGVG
TLLSGDSGFAKPSSVKTKDAGVGQININDNYLVGLKMRHMACGPPQ---LTVGPMASRRS
VGVGGEPLGESM-ENP-QPQAPSGLMTGLDHYIEQVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINFVMKSASTEELRNPDSQKTSLGK--ITGTSLDCIC--K-C
GAL-QPRGP-FSTGTSL----------HEHEAGTT-ERKP------GGSQDAFPTQESVL
SAVNLTDDQIAAG--LFVCT-NNESTLKSIMKKRDGHSDSNG--AKXXXXXXXXXXXYET
TSSDDSSSEESSS-SESDDECDVLEYPPEEEE--------EDEDPQGMAQGHHAVNIEGF
KSTRVE-DEIQVQECEPEKVEIRERYELSEKMLSACNLLKNNLSDPKALAGKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYITAFEAVSPDVLRYI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXX

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

-------MNLGQPGVPGKFAAWGQRHVAKPEKEEVTINGEDEKERKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIRKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KAVPASVGT-KNS---GGQCSGWTSTES-LSSSNS
DEN-K--QSL-ATRSQVTL--SVPAK-PSVSFEVSPTFLTVPEIKQLPPPSPQPPRHNLL
VTKTLMETRRRLEQER-MMQVTP--GDVRRPRLSSFGGMGSTSSLPSFVGSSGYS-HVSQ
HLQNGYQGNGDYGAC-----FSSSLGSSIRHSPMSSGISTPVTNVSPVHLQHIREQMAVA
LKRLKELEEQVKTIPVLQVKISVLQEEKRHMMAELKNHRKATQNDTYGFRKRSYSAGNAE
QWEHMSQVRR---GGELYIDCEE--EMESVEQSSQRIEEFRQLTAEMQALEKKIQDSNYE
SP-ANLRVNR-EGLIKEARSVAVGADENMNDIVIYNRSARQHKEVAVATEKEVRECGVGV
TEAMLGLSTEVEKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPRVVSRMVEAVIQTRDQMVGDHVDVADSSVGNHLQTSSIGTSCRPATRSTAA
GPELLMNRWLVRERADVQDQGTGRSMELHDKSVGTETSVCETGVNTEEPSEVPSPCQVAQ
AEVGAVRSVGCGDCSVDVVVCVPKEHVSRETATEAVPRAEAMVMAVPSTASQQTSTALEM
VSQCTSTEAACLADCGTNTAVSCCDKHTSTDGVELRSVAVGDGRVKDVHASAKMRSVGVG
TVLSSHPGSEKPSAIKTKDCGIGQISVHENYLVGLKMRSIACGPPPLPV----VPTGTRS
IGVGGESVCTPVSGQLESPLPPSELRTGLDHYIERVQKLLQEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKYASTEELRSLDLQKQCVERSTPSGATLEYIPHGQLA
N-----THLTSNLRTLKL---------EQDTVPTQEERKTPLVE-AARGRKSFSSQDKAL
TPINLTDDQLASG--LYVCT-NNESTLKSIMKKKDGKKDLSN--TKKNLQFVGINGGYET
TSSDDSSSEESSS-SDSEEECESREYPCNQHPEEQQ-------PTPR----------AAE
---GGAEKDSPLPECEAEEVEIRERYELSEKMLSACNLLRNNIDDPKALTNKDV------
-----------------RFCLNTIQHEWFRVSSQKSAVPEMVGDYITAFEEISPAVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1299)

NGNTALHYSVSHSNFEIVKLLLDANVCNVNHQNKAGYTPIMLAALAAVEAEKDM
RIVEELFSCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKALLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNSTLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKTQSPG
TPRLSRRTSPGPTHRATFE-

-------------------------------KADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVAS--TPISK-PPAPLETSLPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLSSFMGSGNHN-PATH
QLQNGYQGNGDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRVRR-S-GRELYIDYEEEE-METVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSCKDAAVGTLIEMKNCGVSV
TEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDQCVGRSVEICDKSVSVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCCPKECTSRGVNTEAVSQVEAAVMAVPRTADQNTSTDVEQ
VHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENP-QPQASPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNYLGYTC--K-C
GGL-QSGNP-LSSQTSQ----------LEQEVGTS-EGKP------ICSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNTINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYLAAFEAISPDVLRYV
INLADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSP-
--------------------

---------MAHITKV-NGC--------ASGKAEDVLNGDHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIPKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1253)

KPSVPCPES-RAT---TGQQGVWTSTES-LSSSNS
DDN-KQCPHFLLARSQVTS--TPVPR-PPAPLETSPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGMGSTSSLSSFLGSGNHN-PAMH
QLQNGYQGNGDYGGYVPATATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAVA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRATAQNDACGVRKRSYSAGNAS
QLEQLSRARR--SGGELYIDYEE-EEMESVEQSAQSIREFRQLAADMQALERKIQDSGCQ
P-------------APEGRSVAVGADDTMDSVVVYRRAAGSRRDAAVGTATEMRSCAISV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVMAQPLVGDKMVEAVVPTRDQMAGHHLDVVDACVGTSVQTHSVGVSCQPSRESRLA
GPELPMNCWIVKERVDVRDQCTSRSVEMCDKSVGVETSVCETGSNTEESVNDLSLLKTNL
-NLKEVRSIGCGDCSVDVTVCPPKECTSRSVNTEAISQVDAAVTAVPQTASQHTSTVLGQ
VNQATNTEVATLVESCTNTSVSTLDKQTSTQMVETRTVAIGEGRVKDVNSSAKMRSVGVG
TVLSGSAGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTLGLAASRRS
VGVGDEPVGEFME--SPQLQAPPGMMTGLDHYIERVQKLLAEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFPKMSLGKV--TG-SLEHT--CR-C
GGL-PAGAP-FSSQASR----------HEQAVGPT-EG------RPPGGQDAFPPQESTL
SPVNLTDDQIAAG--LYVCT-NSENTLKSIMKKKDGNRDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEFPPEEEEEE----EEEEEDTRGVAEGQHAVNMEGF
KSAGAE-DEMQVPECEPEKVEIRERYELSEKMLSACHLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSASPAMVGDYIAAFEAI

PF12796 // ENSGT00530000063448_3_Domain_1 (1253, 1311)

SPDVLRYI
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAA

ENSGT00530000063448_3_Linker_1_3 (1311, 1318)

LAAVEAQ

PF12796 // ENSGT00530000063448_3_Domain_3 (1318, 1401)

KDM
RVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCN

PF12796 // ENSGT00530000063448_3_Domain_4 (1318, 1401)

KDMRVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-CASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAPSPG
TPRLGRKTSPAPTHRSSFD-

---------MAYTTKV-NGY--------GAEKADEVLNGDHTKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKVNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSAPCPEV-RAT---PGHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFTIPENRQLLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHN-SAMH
QFQNGYQGNGDYGSYVPATATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNEVCGVRKRSYSAGNAS
QLELLSRTRR--GGGELYIDYEE-EEMESVQQSTQRIKEFRQLTADMQALEQKIQDSSCE
AA-PELQENG-QCPSRECKSVAVGSDENMNDVVVYHRDFRSCKDTAVGTVTETRNFGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVCSKLVEALVPTRDQMVGSHVDTTDSCVGTSVQTSSVGISCQPDHRNQVV
GPELPMNWWVVKERVETHDRCVGKSVETCDQSVGVEVSVCETGSNTEASGSDLTLLKTNL
-DLTDVRSIGCGDCSVDVIVCLPKECASRSMNTEAVGQEEAAVMAVPHTTNQHTSTTLEQ
ADQCTNTEAATLVESCTNTFLSTLDKQTSTQTVEMRTVAIGEGRVKDVNPSTKTRSVGVG
TVLSGSSGFDKPSAVKTKESGVGQISIHDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGSESVGDLVED-LPQPQLASGVVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PNSQIGSLNSQLISTLSSINSVMKSAGTEELRNSDFQKTRLGKS--TGNHLECT---K-C
GSL-RSGRL-LHVPTPQ----------PEQETGMA-EG------NLVRGRDQFPTQGSTL
PPVNLTDGQIATG--LYVCP-NNENTLKSIMKKSDGNKDSNG-GAKKNLQFIGINGGYET
TSSDDSSSDGSSS-SESDDECDTIEYPPEEEEEEE---EEEEDTTRGMAEGQHAVNVEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVADYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSLDVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPSFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQSNVCGVRKRSYSAGNAS
QLEQLSQARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSLETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGMNTEAVGQVEAAVMAVPPTADQDTSTDLEQ
VHQFTSTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VSSLDAFPTQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAISPDVLRYV
INLADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC-------ASEGKADGVLNGDHDREQKDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKVNIQKRRKPSAPGSES-RAT---PGQRGLWASTES-LSSSNS
EES-KHCPIFPIARSQVTS--TPIPR-PPGPLETSPTFLTIPESRHLPPPSPQLPKHNLH
VTKTLMETRRRLEQERISMQAVP--GDFRRPRLASFGGLDSTSSLSSYVGSGNHN-PATH
LLQNGHQGNGDFGGYALATATASSMGSSIRHSPLSSGVSTPVTNVSPMHLQHIREQMAVA
LKRLKELEEQVRTIPVLQVKIAVLQEEKRQLASQLKSQKAASQGEACGVRKRSYSAGNAS
QLGQLSGVRK-R-GGELYIDYEEEEEMESVEQSAQRIQEFRQLTADMQALEQKIQDSGCE
AAPAELRPNG-EHRPPESRSVAVGSNEAMEDIVIYRRAS---RDASVGTVTDRRDFGVGV
TEALLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTRLKQELQAAGSRKK
VDKAIMAQPLVFSKLVEAVVQTRDQMADSHVEMVDTCVGTSVQMNSVGISCWPHCGHQAV
GPELPMNRWIVKERVDMHDRCAGRSLETHDQAVGVEISVCETGSNTEESVKDLTLLRTNL
-SLKDVRSIGCGDCSVDVTVCSPKEHTSQGVNTEAAEQAEASVMAVPHTLTQHTSTVLEQ
VHQCTNTESAILAESCTNTFLSTQDKQTGTQAVEMRTVAVGEGRVKDIISTVKMRSIGVG
TLLSGDSGFDRPSSVKTKESGVGQTSIHDNYLVGLKMRTIACGPAQ---LAVGLSGGRRS
VGVGIESVGELL-EGP-PPPALGGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSAVKSASTEELRNPDTLKLSLGK--VTGSNLECAC--K-C
GGL-QSRGS-LSTQK------------PQQEVGTP-DGKT------------LPAQENTL
PPVNLTDDQIAAG--LYVCA-NNDSTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGXXX
XXXXXXXXXXXXX-XXXXXXXXXTEYLPEEEEE------EEDEGPRGMAEGHHAINIEGF
KSMRVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHER--VSSQKSAXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKGLLACGADVNVQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHAEIVKLLLAQPGCNGHLQDNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC--------ASGKADDPLNEDHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEA-RVP---PAQHGVWTSTES-LSSTNS
DDN-KQCPTLLLARGQVTS--TPGPR-PPPPLETSSAFLPIPENRQLPPPSPQFSKHNLH
VTKTLMETRRRLEQERVTMQMMP--GEFRRPRLASFGGMGSTSSLPSFTSSGNYS--AAT
QLQNGYQGNGDYGGYAPVAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKMQRAASQNDVCGVRKRSYSAGNAS
QLEQLSRARR--SSGELYIDYEE-EEMESVEQSTQRIREFRQLTADMQALEQKIQDSSCE
AS-LVLRENG-QCPPQECRSVAVGSNENMNDIVVYQRSSRACKDAAVGTVTEMKDSCIGV
TEAMLGVTTEADKEIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVTVQPLVFSKLVEAVVSTRDQMVGSHVDLVDTCVGTSMQTSSIGISCQSECKNQVA
GPELPMDRWIVKEKVEMHDQCTGRSVETCDKCVGVEVSVCETGSNTEASVSDLTLLKTNL
-TLKDVRSIGCGDCSVDVTVCSPKERASRAVNTEVVGQVEAAILAVPLTINQHTSTVLEQ
ASQSTNTNTATLVDSCTNTSLSTLDKQTSTHTVEMRTVAIGEGLVKDVNSSTKTRSVGVG
TLLSGNSGFDKPSAVKTKELGVGQINVHDNYLVGLKMRTIACGPPQ---LTMGLTGSRRS
VGVGDGPVGELQE--DPQPQAPSGMVTSLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELKNANFQKTSLGDF--AGNNLEYA--CK-C
GGL-QSTGL-LSAHRSW----------PEREVGTAEEG------TPTRSQETIPSQQSAL
APGHPADTQIASG--LYVCA-NNENTLKSIMKKGDGTKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECGVIECPPEEEEE-----EEENEDIRGMAEGHRAVNMEGF
KSARVD-PEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKMSPGPTHRGSFD-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----CI-QTNPAPQCSP--QEPLGPYELSEKMLSACNLLKNNTNDPKALTSKGV------
-----------------RFCLNTLQHEWFHVSIQKSAVPAMVGDYITAFEAVSPDELCYI
I

PF12796 // ENSGT00530000063448_3_Domain_1 (1262, 1335)

NMADGTGNTALHYSVSHSNFEIVKLLWDTDVCNVDHQNKAGYMPIMLAALAAVEAEKDM
QVVEELFSCGNVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1354)

KASQV---SGLLPDPHERI

PF12796 // ENSGT00530000063448_3_Domain_4 (1354, 1430)

DMVKGLLACGAEVNIQDNKDSTALM-C
ASEHGHMEIVKLLLAQPGCKGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----METRRRLEQERGAMQVVP--GDFRRPRLASFGGLGSAGSLPTFVSSGGHH-PASH
QVANGYQGNGELGVYATAAATTSSMGSSIRHSPLSSGLSTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKSQKPASQSDTYGMRKRSYSAGNAS
QLEQLSQGRK-G-GGELYIDCEEEV-ESVVEQSTQRIKEFRQLTAEMQALEKKIQDSSYE
SS-PELRENG-AGLPKECRSVAVGADENMNDLVVYHRSSKPCREAAVGTETETRDSGVGV
TEAMLGVVTEADKEIELQQQTIEALKEKIFRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVLSRMVEAMVPTRDQMVGSHVAVTDSCVGTQLQTSSVGISCKPALEGRAV
GPELPMSQWIVKERVEVCDQGTGRSVELRDQSVGIETAVCETGSNTEESVDDLTLCATNL
-DLKEVRSIGCGDCSVDVTVCSPKDCVSRSVNTEASCRVDSGVMAVPPTASQHTSTVLEQ
VSQFTNTEVTSLMDSSTNTSLSMHDKQTNTATVEVRSVAVGEGRVKDINASVKVRSIGVG
TLLSSDSGFDKPSVVKTKDSGIGQININDNYLVGLKMRNMACGPPQ---LTDGPTAGRRS
VGVGDDPVGEVV-ESS-QSHPPPKMMTGLSHYIEQVQKLLAEQQTLLTENYSELAEAFEA
PRAQIGSLNSQLISTLSSINSVMKCASTEELRNLDFQKQNLDK--STGHNLEYIS--HGQ
VA--GSAVT-SKSQTTV----------LEQEVVTI-KGEKITMGGMDSVQESFPPQDSAI
SPVNQTDDHIAPG--HFVGT-NNENTLKSIMKKKDGKKDSSS--TKKNLQFVGINGGYET
TSSDESSSDESSS-SESDDECDVNEYSHEEEEE--------ESSPPGTAEGLHAVDQDGF
KPAGIE-DEMQVQGSEPEKVEIRERYELSEKMMSACNLLKNNIDDPKALTSKDM------
-----------------RFCLNTIQHEWFRVSSQKSAIPAMVGDYIAAFEEVSSAVLQHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGTLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKTQSPS
TPRLGRKTSPGPTHRGSFD-

-------VSHSIKRLS-SLS--------PTGKADDVLNGDHDKEQRDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRRKPSVPCPES-RPP---PGQQGVWTSTES-LSSSNS
DDN-RQCPSFLLARSQVTS--TPVAR-LPTPLDISPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQAMP--GDFRRPRLASFGGMGSTGSLSSFMGSGNHI-PVMH
QLQNGYQGNGDYSGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPVHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASKLKNQRAASQNDISGVRKRSYSAGNAS
QLERLSKGPR-S-GGELYIDYEEEE-IESVEQSTQRIREFRQLTADMQALEQKIQSSSYE
AP-SELRENG-ECRPREHRSVAAGADENMHDIVVYHRGSRSWKDAAVGTVTETRDSGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
IDKAMMAQPLVFSKMVEAVVPTRDQMVGRHVDVVDSCVGTSVQTSSVGISCRPHCENKVT
GPELPMNWWIVKERVEMRDQCTGRAVETRDKSVGVEISVCETGSNTEESVNDLMLLKTNL
-NLKEVRSIGCGDCSIDVIVCPPKECTSRSVSTEPAGQAEAAVMAVPHTTSQHTSTALEQ
LNQSTNTETATLVESCTNTSLSTLDKQTSTGTVETRTVAVGEGRVRDINPSTKTRSIGVG
TVLSGSSGLDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLMASRRS
VGVGDEPVGEFL-EGP-QPQAPSGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFPKMSLGK--VAGSNLEYTC--R-C
GGL-QSGGP-LNTQTSR----------HGQEVGFT-EGEP------VCSQDTFPAQESTL
SAVNLTDDQIAAG--LYVCA-SNESTLKSIMKKKDGNRDSNG--AKKNLQFVGINGGYET
TSSDDSSSEESSS-SESEDECDVIEYPPEEEEE----D-EEDEDTRGTAAGHHAVDVEGC
RSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYLAAFAAVSPEVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

GGQTALMLAVSHGRIDMVKGLLAFGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSMPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGSLIEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRFAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNSEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMTTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VSSLDAFPIQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNRDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-------EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MVSGSHN-SAMP
QLQNGYQGNGDYGGYVPTAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLSSQLKNQRAASQNNVCGVRKRSYSAGNTS
QLEQLSQAQR--RGGELYIDYEE-EEMESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AS-LEPRENG-ECQPRECRSVAVGADENMNDIVVYHRGSRSWKDAAVGRVTETRNSGVSV
TEAMLGVTTEADKEIELLQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKGMMAQPLVFSKMVEALVQTREQMVGSHVDMVDTCVGTSVQTTSVGISCQPECVNKVV
GPELPMNWWIVKEKVEMLDQCTGRSVEMCDKSVGVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTICFPKACTSRSMNTEAFGQAEAAVMAVPLTTSQHTNTVLEQ
VHQFTNTETVILTESCTNTSLSTLDKQTSTQAVEMRTVAVGEGRVRDINSSAKMRSIGVG
TLLSGSSGFDKPSAVKTKDSGVGQININDNYLVGLKMRSIACGPPQ---LTAGLAASRRS
VGIGGEPVGEFTE--NPQAQAPSGLMTGLDHYIERVQKLLAEQQMLLTENYSELAEAFGE
PHSQIGSLNSQLISTLSSISSVVKYASTEELRNPDFQKTSLGEL--TGNNLEYP--CK-H
GALLPLGGP-FTSQMSL----------HEEEVGTT-EG------KLNGDPGTFPSQESPL
SPVNLTDDQIAAG--LHGCT-NNESTLKSIMKKKDGNKESNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVTEYPPEEEEE-----EEEDEDTQGVARGHHAVNFEGF
KSTRVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFEAVSPDVLRYV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1299)

NGNTALHYSVSHSNFEIVKLLLDADMCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVRGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKNIALLLYAHVNFAKAPSPA
TPRLGRKTSPGPTHRGSFD-

---------MEQAENL-NGNIYKGYCGDNTGDEENIQIGENDKGGNAAYFVETPYGYQLD
LDFLKYVEDIQKGNTIKKVSLLKKRKLVPNLAEG-RNP---PSQEAGWPSTDS-LSSSNS
DDN-KHSPSLLTRRHTFSN--TA----RPSSQEASPSFLTVPENKPLPPPSPQIPQHNFH
VTKTLMETRRRLEQEKIIMQVASSYNDIRRPRLASFGGMGSTGSLSSVTGTTGHN-ISAQ
QLQNGHQANGDYSAL-----FASSLGSSIRHSPLSSGVSTPVTNVSPMHLQHIREQMATA
LKRLKELEEQVKTIPILQVKISVLQEEKRQLMSEIKSQKLSNQKDTAGFRKRSYSAGNAA
GFEPPSRVRS-A--GELHIDSDD--EMETPEQNSQTLKEFRQLTAEMQALEKKIHDSSLE
SRCPDTQPREIKTKEKCSRSVAVGADENMNDIIIYHKSVKSSQDASVGTEIQVKNLGVGV
TEEMLGVTSEAEREIELQQQTIEALKDKIYRLETDLRETTYAMEMTKLKLEIKAAGSRKN
ADKAIMAQPLMFSRTTEASVEMKDQSAGDHVDIIDACVGNSLKTVSVGVLCSPIVQNAAA
GSSLPMNSWIVKQKVEMCDTGTGRDLDLCDKCVGNDQVLFEDALNIREPIDQ-QDGTGDL
-KTKELRSVGCGDSSVDVIVKPVMESLSCGVNTEFVNKVDSSVTASPCTADQQTNTEMDT
ANQYTNTDTLCCIDSSTNTALSTYSKQTNTETVEMRSVAIGDGKVKEVNSLPKTRSIGVS
TSD---SDFE-SSTPKTKDFGVGHINIMDNFLIGMKSRSIACGPSE---A-LPLGPDTRS
IAVGDEPFQEQECIPLINKEPTPDTPAVIDQYIEQVQKLLQEQQMLLAENYTELAETFGE
PYSQIGTLNSQLISTLSSFNSVMKYGSSEELHSSGFKRHSAELDPSAGSNLDCFP--ESQ
FIS-QYA-N-GNTQTINLNQLPEATQCEVQNVPKS-AGKPSA------------------
---CIPASPAAEGETECVSA-SGQTTLKSIMKRKDEKKESTN--TKKNLQFVGINGGYET
TSSDESSSDDSSS-SESDDECEEEESFNEESGE----------LYHGVA----SV-IPGS
---PSNLEEKQLNEKEPEKVEIRERYELSEKMLSACNVLKDTVSDPKALANKDV------
-----------------RLCLTTVQNEWFRVSSQKSAVAPMVEDYITAFKDLSPAVLSYI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFDIVKLLLDADVCNVN

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

QQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAPKDM
GVVEELFGSGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVRALLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQHGCNAALED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1427)

DGSSALSIALDAGHKDIAVILYAHLNFSKTPSPG
TPRLSRKFPPSPTQKGPTDH

---------MAHTTKV-NGC--------ASGKTDDVLNGDHDKGQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSAPCPEP-RVT---PGPQGVWTSTES-LSSSNS
DDN-KQCPSFLLARGQVTS--TPVPK-PPPPLETSPTFLPIPENRQLPPPSPQFPKHNLH
VTKTLMETRRRLEQERVAMQMSP--GEFRRPRLASFGGMSSTSSLPSFMGSGNYG-AAIH
QLQNGYQGNGDYGGYAPVAATTSSMGSSIRHSPLSSGISTPVTNVSPVHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRAASQNDICGVRKRSYSAGNAS
QLEQLSRARR--SGSELYIDYEE-EEMESMEQSTQRIREFRQLTADMQALEQKIQDSSCE
AS-SALRENG-QCPPQEYRSVAVGGDENMNDIVVYPQGSRACKDAAVGTVTEMRDSGIGV
TEAMLGVTTEADKEIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATTAQPLVFSKLVEAVVPTRDQMVGSHVDLVDACVGTSVQASSVGISCQPECNNQAV
GPELPMNRWIVKERVETHDRCTGRSVETCDECVGVEVSICETGSNTEASVSDLTLLKTNL
-NLKDVRSIGCGDCCVDVTVCSPKEYASRSVNTEAVAQVEAAIMAAPATTDQHTSTVWEQ
VSQSTNTKTTVLVDCCTNTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVNSSTKMRSVGVG
TLLSGNSGFDRPSAVKTKELGVGQINIHDNYLVGLKMRTIACGPPQ---LTMGLTGNRRS
VGVGDEPVGELLE--DPQSQAPSGMVTSLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASTEELKNSDFQKTSLGRI--AGKNLEYT--CQ-C
GGL-L------STQVSW----------PELKVGMA-EG------MPESIQETFPSQEGIP
TPVNLTDDQVASG--LYICT-NNENTLKSIMKKRDGSKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVVEYPPEEE---------ENEDTRGVAEGHHAVNIEGF
KSARVD-HEMQVQACEPEKVEIRERYELSEKMLSACNLLKNSINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSSVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKMSPGPTHRGSFD-

---------MAHTTKV-NGC--------ASGKADDVLNGDHDKEQKDPYFVETPYGFQLD
LDFLKYVDDIQKGNTIKKLNIQKRRKPSVPCPES-RAT---AGQQGVWVSTES-LSSSNS
DDY-KQCPSFLLARSQVTS--TPAPR-PPAPLEISPTFLTIPESRQLPPPSPQLPKHNFH
VTKTLMETRRRLEQERVTMQVTP--GEFRRPRLASFGGMGSTSSLSSFMGSGNHS-SAMH
QLQNGYQGNGDYGAYAPAAATTSSMGSSIHHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQKAASQNDVCGVRKRSYSAGNAC
QLEQLSRARR-N-GRELYIDYEEEE-IESVEQSTQRIKEFRQLTEDMQALEQKIQDSSYE
AS-SELRENG-ECHPRECRSVAVGANENMNDIVVYHRDSRSYKDASVGTVTETRSSGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKMVEAVVQTRDQMVDSHVDIVDTCVGTSVQTSNIGISCQPNHENKVV
GPELPMNWWIVKERVEMRDQCTGRSVETCDKSMGMEISICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVIVCSPKECLSRSTNTEAVGQMEAAVMAVPHTTSQHTSTVWEQ
VNQFTNTETPILIESCTNTSLHMLDKQTNTQTAEMRTVAIGEGRVKDINSSTKTRSIGVG
TVLSGNSGFDRPSAVKTKESSVGQININDNYLVGLKMRTIACGPPP---LTVGLTTSRRS
VGVGDEPVGESV-ESP-QPQAPSGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASTEELRNPDFPKMSLGK--VAGNNLEYTC--K-C
GGL-QSGGP-LNIQTSW----------HEREERST-EGEP------FSSQDTFPSQESTL
SPVNLTDDQIAAG--LYVYT-NNESTLKSIMKKKDGSKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEE-----E-EEDEDTRGMAEGHHAVNMEGC
ESARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAISPDVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RIVEELFGCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1405)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLE

ENSGT00530000063448_3_Linker_4_5 (1405, 1407)

D-

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTS-----------

---------MAHTTKV-NGS--------ASGKAGDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLIARSQVTS--TPISK-PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAMH
QLQNGYQGNGDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-METVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSCKDAAVGTLVEMRNCGVSV
TEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVLTRDQMVGSHMDLVDTCVGTSMETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENP-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNYLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------ISSLDAFPTQEGTL
SPLNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTPGMAEGHHAVNIEGL
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNTINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
------------------------------------------------------------
-------------------EGDVIECPPEEE-E----D-EEDEDSQAMAEGHQAVNVEGF
NSARVE-AEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKTLTSKDMASYQPA
QPRMAILRQSEQCSQHKRFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFEAISPDVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFACGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKGLLACGADVNVQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTAKV-NGC--------ASDKADDVLNRDRDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1253)

KPSVPCPEP-RAT---P---GVWTSTES-LSSSNS
DDN-KQCPNFLLTRSQVTS--TPVPR-PPAPLETSPPFLTTPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAMH
QLQNGFHGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDICGMRKRSYSAGSAS
QLEPPSRARR-S-SRELYIDYDEEE-IESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG-E-----CRSVAVGAEEDINDIVVYHRSSRSCKDAAVGTVIETRNYGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKLVEAVVQTQDQMVGSHTDVVDMCVGTSVQTNSVGISCQPQCKEKIS
GPELPMNWWIVKERVEMHDRCTGRSVDSCDKSVGVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECTSRSMNTEAVGQVEAAVMAVPHTTSQHTSMVLEQ
MNQSTNTEMATLVESCTNTSLSTLDKQTSTQTVEMRTVAVGEGRVKDVNSSTKMRSIGVG
TLLTGNAGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LAVELAASKRS
VGVGDQPVGEFL-ENP-QPEAPSGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASAEELRNPDLQKTSLGK--ITGSNLEYTC--K-C
GSL-QSRGP-LSTQRSP----------PEQEAGTT-DGEA------LSSQDAFPAQECAL
SPVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEEE----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAI

PF12796 // ENSGT00530000063448_3_Domain_1 (1253, 1335)

SPDVLRYV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

------------------------------GKANDILNGEQDREQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKVNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSGPCPDS-RAA---PGQHGVWTSTES-LSSSNS
DDN-RQCPRFLLGRSQVTS--TPISK-PPAPLETSPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGMGSTSSLSSFLGSGNHN-PTMP
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDVCGVRKRSYSAGNAS
QLEQLSRTRR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AS-SELRGNG-ECQPQEFRSVAVGADEDMNDIVVYCRGARSCKDAAVGMVTETRNSGVSV
TEAMLGVTTEADKEIELQQQTIEALKDKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKMVEAVVPTRDQMAGSHVDVVDTCVGTCVQTSSVGISCQPDHENKEV
GPELPMNWWIVKERVEMHDRCIGRSVEMCDKSVGMDISVCETGSNTEESVNDLALLRTNL
-NLKEVRSIGCGDCSVDVTVCSPKECTSRSVNTEAVSQVEAAVMAVPRTVSQHTSTVVEQ
VSQFTNTEVATLTESFTNTSLSTVDKQTSTHTVEMRTVAVGEGRVKDVS-STKMRSIGVG
TVLSGNAGFDRPSAVKTKESGVGQISINDNYLVGLKMRTIACGPPQ---LTVGPTGSRRS
VGVGDEPVGEFV-ESP-QPQAPSGMETGLDHYIERVQKLLAEQQALLAENYSELAEAFGE
PQSQIGSLNSQLISTLSSINSVMKSASLEELRHPDFLKTSLGK--VTGSNLEYTC--K-C
GAL-QSGGP-LNSQTSL------------QEAGTT-EGKP------IGSQDTFPTQESML
SPVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDANKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVPEYPPEEEEE----E-EEDEDTRGMAEGHHAVNVEGF
TSTRVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAISPEVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKMLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFACGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAPSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKAGDILSGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLIARSQVTS--TPISK-PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGTTSSLPSFVGSGNHN-PAKH
QLQNGYQGNGDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-METVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSCKDAAVGTLVEMRNCGVSV
TEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENP-QPQAPLGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNYLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------ISSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGL
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNTINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RIVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

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----------CGDCSVDVIICAPKECISRQTATETVCRAEATVMAVPSTATQQTSTAVEM
VSRC----------------TSSRDQQTSTVSVEMRTVAVGDGRVKDIHASAKTRSVGVG
TLLSSHLALKKNSVIKTKDCGVGQININENYLVGLKMRSIACGPPP---LVVV-PTSTRS
IGVGGEPVCESVSSILENPLPPAELRTGLDHYIERVQKLLQEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKYASTEELRSLDLQKQCMERS--TALAIPYTSQPGSC
GVL-SPFQQ------CQ----------LLSRSGVR-EIKP------AAQTNQFPLCTVIL
ASIGIRNTCFACL--STVCS-NNENTLKSIMKKRDGKKDLSN--TKKNLQFVGINGGYET
TSSDDSSSEDDKVVQQSNSQCKAEKGTPLHALQN-----------INL-FIHHKTVFACF
MAGSIY-DHLQ---CS---------ALVLQRFCSASSSILSTIFDTRCITSENP------
-----------------RFCLNTIQHEWFRVSSQKSAVPEMVGDYITAFEEISPAVLRHI
INVADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1300)

NGNTALHYSVSHSNFEIVKLLLDANVCNVNHQN

ENSGT00530000063448_3_Linker_1_2 (1300, 1301)

K

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RIVEELFSCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKALLACGADVNIQDDEGSTDFIWC
LNGHVALFFCVVIPLQPTLSTDREFD

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFSKTQSPG
TPRLSRKTSPGPTHRATFE-

---------MAYTTKV-NGC--------AVEKADGVLNGDHNKEKKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEV-RAI---PGHQGVWTSTES-LSSSNS
DDS-KQCPSFLIARSHVTS--TPIPR-PPPPLETSPTFAVSENRQLLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVTMQMAP--GDFRRPRLASFGGMGSTSSLPSFMGSANHS-SAIH
QLQNGYQGNGDYSSYVPAAPTTSSMGSSVRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKSQRATSQNEVCGVRKRSYSAGNAS
QLELLARARR--GGGELYIDYEE-EEMESVEQSTQRIQEFRQLTADMQALEQKIQDSSCE
VA-SELRENG-QCPSRECKSVAVGSDENMNDVVVYHRDFRPCKDTAVGTVTETRNVGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEALVPTRDQMVGSHVDTRESCVGTSVQTSSVGTSCHPDCKNQVV
GPELPMNWWVVKERVAMHDQCVGRSVETCDRSVGVEVNVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCFPKECTSRSMNTEAVGREEAAVMAVPHTTDQHTSTNLER
VDQCTNTEAATLVESCTNTLLSTLDKQTSTQTVEMRTVAIGEGRVRDINPSTKTRSVGVG
TVLSGNSEFDKPCAVKTKESGVGQINIQDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGNEPVGELPEE-SPQPRVASGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKASLGKI--TGNHLECT--CK-C
GGL-RSGGL-LNVQPSQ----------PGVEEETA-EG------KHSRGHEQFPTQGNTL
PPVNLTDDQIATG--LYVCP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGINGGYET
TSSDESSSDGSSS-SESDDECDAIGYPPEEEEE----EEEKDLDTRGMAEGHHAVNIEGF
KSARVE-DEVQVPECEPEKEEIRERYELSEKMLSACNLLKYNIKDPKALASKDM------
-----------------RICLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHLNFSKAQSPS
TPRLGRKTSPGPTHRGSFD-

---------MAHPVNI-NGG--------STEKDENALNGEDERDQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVEDIQKGNTIKKLNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KVIPPFATVKNTT---PSQYSGWTSNES-LSSSNS
DDN-KHSSSFCAARSPAAAATSFSTR-PSLSFEASPSFLTIPESKQLFPPSPQLPRHNLH
VTKTLMETRRRLEQEKMAMQASP--GDTRRPRLSSFGAMGSTGSLPSFVGSSGPN-QVSH
PFQNGYQGNGDYSLHLA-----SSLGSSIRHSPLSSGISTPVTNVSPVHLQHIREQMAIA
LKRLKELEEQVKTIPVLQVKISVLQEEKRQIMAKLKNQRIVNQNDTGHFRKRSYSAGNAE
HWKNLSPARG---GGELYIDCED--DAGSIEQSSERIEEFRQLTAEMQALEKKIQDSSYD
NP-ASMRVNR-ASVMKENRSVAVGTDESMDNIVVYNRALRAFRDIAVGTELVTKDFVAGV
TEGMLGLSTEAEREIDLQHQTIEALKDKIYRLEVQLRETTHDREMTKLKHELQAAGSRKK
LDKALMAQPLLFSRAVEAVVQTRDQMVGDRVDIVDSSVGSSLQMSNVGVLCKPMLTNSAV
GPDMPMNWWIVKDREDMRDQCIGSSVETCNQCVGTEISICETGVNTEESVDRLSLCKTEL
-KIKEVRSIGCGACFP------VNETISCSTNTETSCKSDSGVMAVPCTATQGTNTVLEK
TDQLTNTEVATVTDSSTNTFLSTYDKQTNTVIVEMRTVAVGDGRVKDVNAAAKTRSIGVG
TLLSTTSSFDRSSLTKTKDCGVGQININENYLVGLKMRNIACGPPPVSV----APSSTRS
IGVGDESVYESENFVLDCPLPLPEMKTGLDHYIERVQKLVQEQQMLLAENYAELADAFGE
PHSQIGSLNSQIISTLSSINNVMKYASTEELRNLDVPKQCIDRAAETEDNLPNTPHGS-S
---------TSSSLKLK----------LGHEIGTISEEKT-AVQGTGQDWKPSPSQDKTM
SPINLTDDQLASG--LYVCT-S-DSMLKSIMKKKDGKKEEN---AKKNLQFVGINGGYET
TSSDDSSSEESSS-SESDDECVENEYGQIEENGSLL-----------NAEERHGLNR-EE
KSARVE-GVVQDQEPEPEKVEIRERYELSEKMLSACQLLKSSIDDPKAMNSKET------
-----------------RFCLNTIQHEWFRVSSQKSAVPAMVGDYIAAFEEVSPVVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1299)

NGNTALHYSVSHSNFEIVKLLLDANVCNVNHQNKAGYTPIMLAALAAVDAEKDM
RIVEELFACGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKALLACRADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1397)

GSTALM-C
ASEHGHVEIVKLLLAQSGCNGTLEDNDGSTALSIALEAGHKDIAVLLYAHANFSKTQSPG
TPRLGRKPSPGPAHRSPFDC

---------MAHTTKA-DGS--------ASGNAEGVLNGDHDKEQKDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRRKPSVLCADS-RAA---PGQHGVWTSTES-LSSSNS
DDT-KQCPHFLLARSQVTS--TPIPR-PPAPLETSPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVAMQVAP--AEFRRPRLASFGGMGSTSSLSSFMGSGNHN-PAMN
QLQNGYQGNGDYGGYVPAAATTSSMGSSLHHSPLSSGISTPVTNVSPMHLQHIREQMAVA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLALQLKHQRATAQNEVGGVRKRSYSAGNAA
QLQELSRARR---GGELYIDYEE-EEVKSVEQSTQGIREFRQLAADMRALEQKIQDSSCG
AS-SEPQENR-E-----CRSVAVGADENMDHVVVYRRGPGTCRDAAVGTVTETRSSGVGV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTRLKQELQAAGSRKK
VDKAMMAQPLVCSKMVEAVVPTRDQMAGRHMDVADTCVGTSVQTHSVGVSCQPSCESRAA
GPELPMNWWIVKERVELRDQCTGRSLETCDKSVGVEISVCETGSNTEESVNDLSLLKTNL
-NLKEVRSIGCGDCSVDVTVCPPKERTSRSVNTEAVSQVEAAVMAVPPTTSQHTSTVWEQ
VTQFTNTEVAILVDSCTNTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVNSSAKMRSIGVG
TVLSGNSGFDRPSAVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---VTLGLAASRRS
IGVGDEPVGEFTE--SPQPQAPSGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQISSLNSQLISTLSSINSVMKSASTEELRNPDFPKMSLGKV--TGSSLEYT--CK-C
GGL-QAGAP-FNTQTSR----------HEQAVGST-EG------APFGGQDTFPSQESTL
PPVNLTDDQIAAG--LYVCA-NGESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEED-----EEEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSASPAMVGDYIAAFEAISPDVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVRGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRSSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1253)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPDFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSQARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDCCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------INSLDAFPTQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEVI

PF12796 // ENSGT00530000063448_3_Domain_1 (1253, 1335)

SPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

-------------------S--------LPGTADDVLNGDHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSVPCSEA-RAA---PGQQAVWTSTDS-LSSSNS
DDS-KQCPSFLLARSQVTS--TPVSR-PPAPLESSPAFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVTP--GEFRRPRLASFGGLGSTSSLPSYMGSANHN-SAMH
QLQNGYQGNGDYGGYAPVAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKDQRAASQNDAWGVRKRSYSAGNAS
QLDQLSRTRR--GGGELYIDYEE-GEMESAEQSTQRIREFRQLTADMQALEQKIQDSSGD
AS-WEPTENG-QCRPRECRSVAVGADEDMNATVVYHRGSRGCRDAAVGTVTETRNSGVSV
TEAMLGVTTEADKEIELQQQTIDALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKR
ADKATMAQPLVFSQMVEAVVQTRDQMVGRHVDMVNACVGTSVQTKSVGISCQPEGKDQDA
GPELPMSCWVVKERVETRDQCTGRTLDTCDKSVGVEVSVCETGSNTEESVNDLTLLKTNL
-HLKDVRSIGCGDCSVDVMVCSPTERASRSVNTEAVGRVEVAVTAAPHTTDRHTSTALQQ
ASQSTNTETASFAEASTNTCLSTLDKQTSTQTVETRTVAVGEGRVRDVNSSTKTRSVGVG
TVLSGNSGLDRPSAVKTKESGVGQININDSYLVGLKMRTIACGPPQ---LTVGPVASRRS
VGVGDEPVGEFLE--NPQAQAPSGVMTSLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEGLRNPDLQKIRLGDM--TGNTLECT--CK-C
RGL-VSGGH-LTSQTDQ----------EV----ETTEG------RPISSRVAFPAQESSS
SPVNLTDDQIAAG--LYVGT-NNENTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDALEYPH----------------TRGMAEGHHAVNVEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFAAISPEVLRYV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLEADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPAHRGSFD-

-------MAHTT--KV-NGC--------ASGKADDILNGEQDREQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKVNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSGPCPDS-RAA---PGQHGVWTSTES-LSSSNS
DDN-RQCPRFLLARSQVTS--TPISK-PPAPLETSPAFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGMGSTSSLSSFLGSGNHN-PTMP
QLQNGYQGNGDYGGYAPPAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDVCGVRKRSYSAGNAS
QLEQLSRTRR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AS-SELRENG-ECQPQEFRSVAVGADEDMNDIVVYRRGARPCKDAAVGVVTETRNSGVSV
TEAMLGVTTEADKEIELQQQTIEALKDKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVMAQPLVFSKMVEVVVPTRDQMAGSHVDVVDTCVGTCMQTSSVGISCQPDHENKEV
GPELPMNWWIVKERVEMHDRCIGRWVEMCDKSVGMDISVCETGSNTEESVSDLALLRTNL
-NLKEVRSIGCGDCSVDVTVCSPKECTSRSVNTEAVSQVDAAVMAVPRAVSQHTSTVLEQ
VSRFTNTEVATLTESCTNTSLSTVDKQTSTHTVEMRTVAVGEGRVKDVS-STKMRSIGVG
TVLSGNAGFDRPSAVKTKESGVGQISINDNYLVGLKMRTIACGPPQ---LTVGPTGSRGG
VGGGDEPVGEFM-ESP-QPQAPSGMETGLDHYIERVQKLLAEQQALLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASLEELRHPDFLKTSLGK--VTGSNLEYTC--K-C
GGL-QSGGP-LNSQTSL------------QEVGTT-EGKP------IGSQDAFPTQESML
SPVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDANKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVPEYPPEEEEEE---E-EEDEDTRGMSEGHHAVNVEGF
TSTRVE-DEIQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAISPEVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKMLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFACGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMIP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARG-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKMRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VNSLDAFPTQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNNEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAYTTKV-NGY--------GAEKADDVLNGDHNKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKRLNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1255)

KPSAPCPEV-RAT---SAHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFAIPENRQLLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHN-SAMH
QLQNGYQGNGDYGSYVPAAATTSSKGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNEACGVRKRSYSAGNAS
QLELLSRTRR--GGGELYIDYEE-EEMESVQQSTQRIKEFRQLTADMQALEQKIQDSSCE
AP-SELRENG-QCPSRECKSVAVGSDENMSDIVVYHRDFRSCKDTAVGTVTETRNFGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGCRKK
VDKATMAQPLVFSKLVEALVPTRDQKVGSHVDTTDSCVGTSVQTSSVGVSCQPDCKNQVV
GPELPMNWWVVKERVEMHDRCIGKSVETCDQIVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCFPKECTSRSMNTEAVGHEEAAIMAVPHTTNQHTSTTLEQ
VDQCTNTEAATLVESCTNTFLSTLDKQTSTQTVEMRTVAIGEGRVKDIHPSTKTRSVGVG
TVLSSNSGFDKPSAVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGNEPVGDLLQD-PPQTQLASGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSANTEELRNPDFQKTRLGKV--TGNHLECI--CM-C
GGL-RSEGL-LNVPMP------------EQEAGMA-EG------KLVRGRDQFPTQGNTL
SPVNLTDDQIATG--LYAYP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGINGGYET
TSSDDSSSDGSSS-SESDDECDTIEYPPEEEEEE---EEEEDDDTQGMAEGHPAVNIEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYITAFEAVSP

PF12796 // ENSGT00530000063448_3_Domain_1 (1255, 1335)

DVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNSQLEDNDGSSALSIALEAGHKDIALLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC--------ASGKTDDVLNGDHDKGQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSAPCPEP-RVT---PGPQGVWTSTES-LSSSNS
DDN-KQCPSFLLARGQVTS--TPVPK-PPPPLETSPTFLPIPENRQLPPPSPQFPKHNLH
VTKTLMETRRRLEQERVAMQMSP--GEFRRPRLASFGGMSSTSSLPSFMGSGNYG-AAIH
QLQNGYQGNGDYGGYAPVAATTSSMGSSIRHSPLSSGISTPVTNVSPVHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRAASQNDICGVRKRSYSAGNAS
QLEQLSRARR--SGSELYIDYEE-EEMESMEQSTQRIREFRQLTADMQALEQKIQDSSCE
AS-SALRENG-QCPPQEYRSVAVGGDENMNDIVVYPQGSRACKDAAVGTVTEMRDSGIGV
TEAMLGVTTEADKEIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATTAQPLVFSKLVEAVVPTRDQMVGSHVDLVDACVGTSVQASSVGISCQPECNNQAV
GPELPMNRWIVKERVETHDRCTGRSVETCDECVGVEVSICETGSNTEASVSDLTLLKTNL
-NLKDVRSIGCGDCCVDVTVCSPKEYASRSVNTEAVAQVEAAIMAAPATTDQHTSTVWEQ
VSQSTNTKTTVLVDCCTNTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVNSSTKMRSVGVG
TLLSGNSGFDRPSAVKTKELGVGQINIHDNYLVGLKMRTIACGPPQ---LTMGLTGNRRS
VGVGDEPVGELLE--DPQSQAPSGMVTSLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASTEELKNSDFQKTSLGRI--AGKNLEYT--CQ-C
GGL-L------STQVSW----------PELKVGMA-EG------MPESIQETFPSQEGIP
TPVNLTDDQVASG--LYICT-NNENTLKSIMKKRDGSKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVVEYPPEEE---------ENEDTRGVAEGHHAVNIEGF
KSARVD-HEMQVQACEPEKVEIRERYELSEKMLSACNLLKNSINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSSVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKMSPGPTHRGSFD-

-------EAHTS--NP-NCC-------KYLGKADDTLNGEQDREQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKVNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1253)

KPSGPCPDS-RAA---PGQHSVWTSTES-LSSSNS
DDN-RQCPRFLLARSQVTS--TPISK-PPAPLETSPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGMGSTSSLSSFLGSGNYN-PTMP
QLQNGYQGNGDYGGYAPPAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDVCGVRKRSYSAGNAS
QLEQLSRTRR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AS-SELRENG-ECQPQEFRSVAVGTDEDMNDIVVYRRGARPCKDAAVGVVTETRNSGVSV
TEAMLGVTTEADKEIELQQQTIEALKDKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVMAQPLVFSKMVEVVVPTRDQMAGSHVDVVDTCVGTCVQTSSVGISCQPDRENKEV
GPELPMNWWIVKERVEMHDRCIGRSVEMCDKSVGMDISVCETGSNTEESVSDLALLRTNL
-NLKEVRSIGCGDCSVDVTVCSPKECTSRSVNTEAVSQVEAAVMAVPQTVSQHTSTVLEQ
VSQFTNTEVAALTESCTNTSLSTVDKQTSTRTVEMRTVAVGEGRVKDVS-STKMRSIGVG
TVLSGNAGFDRPSAVKTKESGVGQISINDNYLVGLKMRTIACGPPQ---LTVGPTGSRRS
VGVGDEPVGEFV-ESP-QPQAPSGMETGLDHYIERVQKLLAEQQALLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASLEELRHPDFLKTSLGK--VTGSNLEYTC--K-C
GGL-QSGGP-LNSQTSL------------QEVGTM-EGKP------IGSQDTFPTQESML
SPVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDANKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVPEYPPEEEEEE---E-EEDEDTRGMAEGHHAVNVEGF
TSTRVE-DEIQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAI

PF12796 // ENSGT00530000063448_3_Domain_1 (1253, 1335)

SPEVLRHV
INMADGNGNTALHYSVSHSNFEIVKMLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFACGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAYTTKV-NGH--------GTEKADGVLNGDHNKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1255)

KPSAPCPEV-RAT---PAHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHTTS--TPIPR-PPVPLEASPAFVIPENRQLLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHN-SAMH
QLQNGYQGNGDYGSYVPA--TTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNEACGVRKRSYSAGNAS
QLELLSRTRR--GGGELYIDYEE-EEMESVQQSTQRIKEFRQLTADMQALEQKIQDSSYE
AP-SELRENG-QCPARECKSVAVGSDEKMSDIVVYHRDVRACKDTAVGTVTETRNFGIGV
TEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEALVPTRDQMVGSHVDTTDSCVGTSVQTSSVGISCQPDCKSEVV
GPELPMNWWVVKERVEMRDRCIGKSVETCDRSVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCFPKECTSRSMNTEAVGQEEVAIMAVPHTTNQHTSTTLEQ
VDQCMNTEAATLVESCTNTFLSTLDKQTSTQTVEMRTVAIGEGRVKDINPSTKTRSVGVG
TVLSGNSGFDKPCAVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGNEPVEDLLED-PPQPQLAPGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTRLGKT--PGNHLECT--CK-C
GGL-RSEGL-LNVPVPQ----------PERETGMV-EG------KLVRGRDQFLTQGNTL
SPVNLTDDQIATG--LYVYP-NNENTLKSIMKKSDGNKDSNG--TKKNLQFIGINGGYET
TSSDDSSSDGSSS-SESDDECDTIECPPEEEEE-----EEEEDDTRGMAEGHHAINIEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYITAFEAVSP

PF12796 // ENSGT00530000063448_3_Domain_1 (1255, 1335)

DVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNSQLEDNDGSTALSIALEAGHKDIALLLYAHGNFAKAPSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASEKADDVLNGDHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1253)

KPSVPCSEP-RAT---PGQQGVWTSTES-LSSSNS
DDN-KQCPSFLLARSQVTS--TPIPR-PPAPLETSPTFLTIPENRQLPPASPQLPKHNLH
VTKTLMETRRRLEQEKVTMQMTP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHN-PAMH
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDVCGVRKRSYSAGNAS
QLEQLSRTRR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SALRENG------ECRSVAVGAEENMNDIVVYHRGSRSYKDATVGTVIETRNSAVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAIMAQPLVFSKMVEAVVQTRDQMVGSHVDLVDTCVGTSVQTNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMRDRCTGRSVVTCDKSVGVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCPPKEFTSRSMNTEAVGQVEAAIMAVPHTTNQHTSTVLEQ
VNQSTNTEMATLVESYTNTSLSTLDKQTSTQTVETRTVAVGEGRVKDVNSSTKTRSIGVG
TLLSGHSGFDKPSAVKTKESGVGQISINDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDEPVGEFL-ESP-QPQAPSGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSANTEELRNADFQKSSLGK--ITGNNLEHTC--K-C
GEP-QSGGL-LSIQISQ----------PEQEVETS-EGKP------IGSQDTFPTQETML
SPVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIDYPPEEEEE----E-EEDEDTRGMAEGHHAINIEGF
KSARVE-DEIQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAI

PF12796 // ENSGT00530000063448_3_Domain_1 (1253, 1335)

SPDVLRYV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFACGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQSGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

MVFARGPAKFTQML-E-LFS--------LWGKADDILNGDRDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1261)

KPSVPCPEP-RAA---P---GVWTSTES-LSSSNS
DDNRQQCPNFLLARSQVTS--TPVPR-PPAPLETSPPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMTP--GEFRRPRLASFGGMGSTSSLSSFMGSGNHN-PAMH
QLQNGYHGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDICGMRKRSYSAGNAS
QLEPPSRARR-S-SGELYIDYEEEE-IESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-AELRENG-E-----CRSVAVGAEEDMNDIVVYHRSSRSCKDAAVGTVIETRNYGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKLVEAVVQTRDQMVGSHVDVVDTCVGTSVQTNSVGVSCRPQCKEKVS
GPELPMNRWIVKERVEMHDRCTGRSVDWCDKSVGVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECTSRSVNTEAVGQVEAAVMAVPHTTSQHTSTVLEQ
VNQSTNTEMATLVESCTNTSLSSLDKQTSTYTVEMRTVAVGEGRVKDINSSTKMRSIGVG
TLLTGNAGFDRPSAVKTKESGVGQINVNDNYLVGLKMRTIACGPPQ---LAVGPPASRRS
VGVGDEPVGEVL-ENP-PAQAPSGM-TGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASAEELRNPDLQKANLGK--ITGSNLEYTC--K-C
GSL-QSRGP-LSTQISQ----------PEQEVGTT-DGKA------LSSQDTFPTEECAL
SAVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEEEE---E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDSKALSSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFEAISPDVLRYV

PF13637 // ENSGT00530000063448_3_Domain_1 (1261, 1288)

INMADGNGNTALHYSVSHSNFEIVKLL

ENSGT00530000063448_3_Linker_1_3 (1288, 1313)

LDADVCNVDHQNKAGYTPIMLAALA

PF12796 // ENSGT00530000063448_3_Domain_3 (1313, 1400)

AVEAEKDM
RVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGC

PF12796 // ENSGT00530000063448_3_Domain_4 (1313, 1400)

AVEAEKDMRVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-CASEHGHVEIVKLLLAQPGCNGHLEDNVSCFPCA--SRPGPRG------------------
---LGLEC------------

---------MAYTTKV-NGY--------GAEKADDVLNGDHNKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKRLNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1255)

KPSAPCPEV-RAT---SAHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFAIPENRQLLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHN-SAMH
QLQNGYQGNGDYGSYVPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNEACGVRKRSYSAGNAS
QLELLSRTRR--GGGELYIDYEE-EEMESVQQSTQRIKEFRQLTADMQALEQKIQDSSCE
AP-SELRENG-QCPSRECKSVAVGSDENMSDIVVYHRDFRSCKDTAVGTVTETRNFGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGCRKK
VDKATMAQPLVFSKLVEALVPTRDQKVGSHVDTTDSCVGTSVQTSSVGVSCQPDCKNQVV
GPELPMNWWVVKERVEMHDRCIGKSVETCDQIVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCFPKECTSRSMNTEAVGHEEAAIMAVPHTTNQHTSTTLEQ
VDQCTNTEAATLVESCTNTFLSTLDKQTSTQTVEMRTVAIGEGRVKDIHPSTKTRSVGVG
TVLSSNSGFDKPSAVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGNEPVGDLLQD-PPQTQLASGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSANTEELRNPDFQKTRLGKV--TGNHLECI--CM-C
GGL-RSEGL-LNVPMP------------EQEAGMA-EG------KLVRGRDQFPTQGNTL
SPVNLTDDQIATG--LYAYP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGINGGYET
TSSDDSSSDGSSS-SESDDECDTIEYPPEEEEEEE--EEEEDDDTQGMAEGHPAVNIEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYITAFEAVSP

PF12796 // ENSGT00530000063448_3_Domain_1 (1255, 1335)

DVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNSQLEDNDGSSALSIALEAGHKDIALLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MSHTTKV-NGS--------ASGKADDSLNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLIIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVQCPEP-RTT---SGQQGVWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPIPK-PPAPLETSLPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTGSLPSFVGSGNHN-PAMH
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDLCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSSKDAAVGTVIEMRNYGVNV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVAQTRDQIVGSHTVLVDTCVGTSVQTNSVGISCQPECKNKVV
GTELPMNWWIVKERVETHDQCTGKSVEMCDKSVSVEVSVCETGSNTEESVNDLTLLKTNL
-NIKEVRSIGCGDCSVDVTVCSPKEYTSQGVNTEALGQVEAAVMAVPLTTDQDTSTDLEQ
VHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDVNSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTAGLTASKRS
VGVGDDPVGESQ-ENP-QPQVPPGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITDNNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VSSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEEE----E-EEDEDTRGMAQGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHSTEL-NGC--------APGKADKVLNGDHDKEQKDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRRKPSVPCRET-RAT---AGQPGLWASTES-LSSSNS
DES-KQCPSFPPTRSQVTS--TPVPR-LPAPLETSPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVSMQVAQ--GEFRRPRLASFGGLGSTSSLTSYMGSASHNAPAMH
QLQNGYQGNGDYGGYAPAPATTSSMGSSVRHSPLSSGISTPVTNVSPMHLQHIREQMAVA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKSQRAASQNDASGVRKRSYSAGNAS
QLDQLSRVRR--RGGELYIDYEE-EEIESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AT-PELRENG-QYQAPECRSVAVGPDEVMDDVVVYHRVSKGRKDAAVGTAIDSRDLGVGV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKHELQAAGSRTK
VDRAVLAQPLVCSKMVEAVVPTRDQMCGEHVAMADACVGASVQPRSVGVSCQPDYEHKAV
GPALPMDSWIVKERVETHDRGTGRALETCEKSVGVEVGRCETGSNTDEPVGGLTQPQSHP
-ELRDVRSVGCGDCSVQVTVRPLQACTSRAVSTEAVGQVEAAVMAVPRTASQHTSTAAVQ
ADRATNTETATLRESCTSTTLSTLDKQTSTQAVELRTVAVGEGRVRDVSPAVKTRSVGVG
TVLSGQAGFDRPSAAKTKEAGVGQISISDNYLVGLKMRTIACGPPP---LPVGAPASRRS
VGVGDQPIGEWLG--DPPPPAPPGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNADFTRTSLGKV--TANNMLHV--CK-C
GVL-QSGAS-SNT---Q----------HLEEMGTP-EG------RSLSDQRTITSQENPL
CPVNLTDDQIATG--LYACT-NSESTLKSIMKKKDGIKDSNG--AKKNLQFVGINGGYET
TSSDDSSSEESSS-SESDDECGVLESPPAEEEE-----EAEDEDIRGVAEGRPGVTVEGF
KSARVE-DEVQVHDCEPEKVEIRERYELSEKMLSACNLLKNNIHDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFEAISPDVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

-GQTALMLAVSHGRIDMVKGLLACGADVNTQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1405)

EGSTALM-C
AHEHGHVEIAKLLVAQPSCNGHFE

ENSGT00530000063448_3_Linker_4_5 (1405, 1407)

DN

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKASSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC--------TSGKADDVLNGDHDKGQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1255)

KPSVPCPET-RVT---PGQQDVWTSTES-LSSSNS
DDN-KQCPSFLLARGQVTS--TPAPR-PPPPLETSPTFLPIPENRQLPPPSPQFPKHNFH
VTKTLMETRRRLEQERVTMQMTP--AEFRRPRLASFGGMGSTSSLPSFMGSGNYS--AAI
QLQNGYQGNGDYGSYAPVAATTSSMGSSIRHSPLSSGVSTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRAASQNDLCGVRKRSYSAGNAS
QLDQLSRAR-R-SGGELYIDYEE-EEMESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-LVLRENG-QCPAQECRSVAVGGNENMHDIVVYQRSSRAFKDTGVGTVTEMRDSSVGV
TEAMLGVTTEADKEIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVMAQPVVFSKLVEAVMSTRDQMVGSHVDLVDTCVGTSVQTSSVGISCQSEHRNQAV
GPELPMNRWIVKERVEMHNRCTGRSVETCDKHVGVEVSVCETGSNTEASVSDLTLLKTNL
-NLKDVRSIGCGDCSIHVTVCSPKEYISHGVNTEVVGQVEAAVMAAPLTTNQHTSTLLEQ
MSQSTNTETATLVDSCTSTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVTSSTKTRSVGVG
TLLSGTSEFDKPSAVKTKELGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLTGSRRS
VGVGDEPVGELLE--ESQPQAPTGMVTSLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASAEEFKNTDFQKISVGKI--AGNNLEYT--CK-C
GGL-QSGEL-S-----Q----------SEREVGTS-EG------SPMSSQMTFPSQESTL
APVNLTDDQIASG--LYVCA-NNENTLKSIMKKRDGNKDANG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVTEYPPEEEEEE----EEENEDTRGMAEGHHAVNIEGF
KSARVD-HETQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYLAAFRAVSP

PF12796 // ENSGT00530000063448_3_Domain_1 (1255, 1335)

GVLRYV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAPSPG
TPRLGRKMSPGPAHRGSFD-

---------MAYTTKV-NGC--------AAEKADGVLNGDHNKEKKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEV-RAI---PGHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFAVSENRQLLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVTMQMAP--GDFRRPRLASFGGMGSTSSLPSFVGSANHS-SAIH
QLQNGYQGNGDYNSYVPAAPTTSSMGSSVRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKSQRASSQNEACGVRKRSYSAGNAS
QLELLARARR--GGGELYIDYEE-EEMESVEQSTQRIQEFRQLTADMRALEQKIQDSSCE
VA-SELRENG-QCPSRECKSVAVGSDENMNDVVVYHRDLRPCKDTAVGTVTETRNVGISV
SEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEALVPTRDQMVGSHVDTRESCVGTSVQTSSVGTSCHPDCKNQVV
GSELPMNWWVVKERVAMHDQCVGRSVETCDRSVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCPVDVIVCFPKECTSRSMNTEAVGREEAAVMAVPHTTDQHTSTNLER
VDQCTNTEAATLVESCTNTLLSTLDKQTSTQTVEMRTVAIGEGRVRDINPSTKTRSVGVG
TVLSGNSEFDKPCAVKTKESGVGQINIQDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGNEPVGELPEE-SPQPRVASGMVTGLDHYIERVQRLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKASLGKT--TGNHLEYT--CK-C
GGL-RSGGL-LNVQPSQ----------PEVEAETA-EG------KHSRGHEQFPMQGSTL
PPVNLTDDQIATG--LYVCP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGINGGYET
TSSDESSSDGSSS-SESDDECDTIGYPPEEEEE----EEEKDHDTRGMAEGHHAVNIEGF
KSARVE-DEVQVPECEPEKEEIRERYELSEKMLSACNLLKYNIKDPKALASKDM------
-----------------RICLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDSSTALSIALEAGHKDIAVLLYAHLNFSKAQSPS
TPRLGRKTSPGPTHRGSFD-

---------MASTTKV-NGC--------ASDKAADVLNGDGDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1261)

KPSVPCPEA-RAT---PGQQGVWTSTES-LSSSNS
DDN-KQCSSFLLASSQVTS--TPVPR-PPAPLETSPTFLTIPENRQLPPPSPQLPKFNLH
VTKTLMETRRRLEQEKGTMQMAP--GEFRRPRLASFGGMGSTSSLPSYMGSGNHN-PAMH
QLQNGYQGNGDYGSYAPAPGTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKSQRAAAQSDVCGVRKRSYSAGNAS
QLELLSRARR--GGGELYIDYEE-EEMESVEQSTQRIREFRQLTADMQALEQKIQDSSCE
VS-SEVRENG-QCPSKACRSVAVGDNENMNDIVVYHKDFRSCRDAATGTVTDTKNFGVSV
TEAMLGVVTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKR
VDKATMAQPLVSSKLVEAVVQTRDQMVGSHVDMVDTCVGTSVHTNSVGIACQPEYKHQVV
GPELPMNWWIVKERVEVHDRCIGRSVETCDQSVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCFPKECASRSVNTETVGHVEVAVMAAPHTANQHTSTALEQ
VERSTNTEAATLVDSCTSTALSTLDKQTSTQTVGTRTIAVGEGRVKDVNSSTKTRSVSIG
TVLSGNSGFDRPSVVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---LSVGLTGSRRS
VGVGNEPVGDLVE--DTQPQVASGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNTDFQKSSLSKI--TGNDLDCI--CK-C
GGL-QSGEL-LGMQTSR----------SEHKVGTT-EG------KPIMSQDSLPSQGTIP
AAVNLTDDQMAAG--LYACP-NNENTLKSIMKKKDGNKDANG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVTQYPPEEAEE-----EEEDEDTRGMAQGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTNKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVSDYISAFAAISRDVLRYI

PF13637 // ENSGT00530000063448_3_Domain_1 (1261, 1288)

INMADGNGNTALHYSVSHSNFEIVKLLLGADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKMSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMIP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARG-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VNSLDAFPTQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTAKA-NGC--------ASGKADDVLNGDHDKEHKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSVPCPET-RAT---PGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPVPR-PPAPLETSPTFLTIPESRQLPPPSPQLSKHNLH
VTKTLMETRRRLEQERVTMQ-TP--GEFRRPRLASFGGMGSTSSLSSFMGSGNHN-PAMH
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLSSQLKNQRAACQNDVCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEDEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AS-SELRENG-QSQPPECRSVAVGADEHMDNIVVYHRGSRSCKDAAVGTVTETRNSGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVYSKMVEAVVQTRDQMAGSHVDMVDTCVGTSVQTNSIGISCQPDCENKVV
GPELPMNWWIVKERVEMRDRCTGRSVETCDKSVGVDISVCETGSNTEESVKDLTLLKTNL
-SLKEVRSIGCGDCSVDVTVCSPKECTSRSMNTEDVSQVEAAVMAVPHTTSQHTNTILEQ
VNQFTNTETATLTESCTNTSLSTSDKQTSTQTVEMRTVAIGEGRVKDINSSAKTRSIGVG
TVLSGTSGFDRPSAVKTKELGVGQININDNYLVGLKMRTIACGPPQ---LTVGPTASRRS
IGVGDEPVGEFE-ESP-QPQAPSRMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNLDFPKTSLGR--VTGNNLEYTC--K-C
GSL-QSGGL-LNTQTSQ----------HEREVGTA-DERP------IGSQDAFLAQEGTL
SPVNLTDDQIASG--LYVCT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDAIEYPPEEEEE----E-EEDEDTRGMAEGHHAVNVEGF
KSTRVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAISPDVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

-------MKSPRPARPGL-RRRGSFF-SLWEKEEVIINGKDENERKY

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1260)

KAVPASTST-KNA---GGHCGDWTSTES-LSSSNS
DEN-K--QSFLAARSQVVS--SAAVR-PLASLEASPSYLTVPESKQLPPPSPQLPRHNLH
VTKTLMETRRRLEQER-MMQVMP--GDVRRPRLSSFGGMGSTSSLPSFVGSSGYG-HLPQ
QLHNGYQGNGDFGAC-----FGSSLGSSIRHSPMSSGISTPVTNVSPVHLQQIREQMAIA
LKRLKELEEQVKTIPVLQVKISVLQEEKRHMMAELKSQRKSSQNDVYGFRKRSYSAGNAE
QWEHLSQVRR---GGELYIDCED--EMESAEQSSRRVEEFRQLTAEMQALEKKIQDSNYE
VP-SNLR----ESLTKESRSVAVGADENMNDVVIYNRSSRQHREVAVGTEKEMRESGVGV
TEAMLGLSTEVEKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVVSRMVEAVVQMRDQMVGDHVHVADSSVGSHLQMSSVGTSCRPAVRSTAA
GPELLMSRWLVRERAEMRDQCTGRCVELLDKKVGVETSVCETGVNTEESVGDLSLCRTAR
-EVRETRSIGCGDCSVDVVVCAPKECVSRQTATETVCRAEATVMAVPSTATQQTSTAMEM
VSRCTNTEAPVAVDCGTNTVPSSRDQQTSTVSVEMRTVAVGDGRVKDIHASAKMRSVGVG
TLLSSHPGFEKLSVIKTKDCGVGQININENYLVGLKMRSIACGPPPLVV----VPTSTRS
IGVGGDPVCESVSSLLESPLPPPELRTGLDHYIERVQKLLQEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKYASTEELRSLDLQKQCMEKSTASGATLEYIPHGQLA
N-----THLTSNLRALKL---------EQDAVPAQEEKTTPLVEA-ARGRKSFSSQDKTL
AAINLTDDQLASG--LYVCS-NSENTLKSIMKKRDGKKDLSN--TKKNLQFVGINGGYET
TSSDDSSSEESSS-SDSEEECEGHAYPHDHVTDGEH-------PVLG----------PPE
TSAAGTAKDGPPLECEAEEVEIRERYELSEKMLSACHLLKNNIDDPKALTNKDV------
-----------------RFCLNTIQHEWFRVSSQKSAVPEMVGDYITAFEEISPAVLRH

PF12796 // ENSGT00530000063448_3_Domain_1 (1260, 1335)

I
INVADGNGNTALHYSVSHSNFEIVKLLLDANVCNVNHQNKAGYTPIMLAALAAVEAEKDM
RIVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKALLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGTLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKTQSPG
TPRLSRKTSPGPTHRATFE-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMIP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARG-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QSQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VNSLDAFPTQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGN--------ASGKADDSLNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVRCLEP-RTT---SGQQGVWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPIPK-PSAPLETSLPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTGSLPSFVGSGNHN-PAMH
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPTHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDLCGVRKRSYSAGNAS
QLEQLSRARR-S-VGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDVVVYHRGSRSFKDAAVGTVIEMRNYGVNV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAHPLVFSKVVEAVVQTRDQIVGSHAVLVDTCVGTSVQTNSVGISCQPEWKNKVV
GPELPMNWWIVKERVEMHDQCTGKSVEMCDKSVSVEVSVCETGSNTEESVSDLTLLKTNL
-NIKEVRSIGCGDCSVDVTVCSPKEYTSQGVNTEALGQVEAAVMAVPHTADQDTSTGLEQ
VHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDVNSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENP-QPQVPPGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNNLGHTC--K-C
GGL-QSGSP-LSSQTSQ----------PKQEVGTS-EGKP------LSSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-SNESTLKSIMKKKDGNKDSKG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEEE----E-EEDEDTRGMAQGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC--------ASEKADDILNGDHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKKK

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPET-RVT---SGQQGAWTSTES-LSSSNS
DDN-KQCPSFLLARSHVTS--TPIPK-PPAPLETLPTFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMTP--SEFRRPRLASFGGMGSTSSLPSFMGSGNHN-PAMH
QLQNGYQGNGDYGGYAPGAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRAASQNDVCGVRKRSYSAGNAS
QMEQLSRARR--SGGELYIDYEE-DEMESVEQSTQRIKEFRQLTADMQALEQKIQDSSYE
AY-SELRENG-ECPPRECRSVAVGDDESMNDLVVYHRGSVCCKDAATGTVTEMRHCGVNV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTRLKQELQAAGSRKK
VDKATMAQPLVSSKLVEAVVPMRDQVVGHHVDVVDTCVGTSVQTSSIGISCQPQCRNQAV
GPELPMNWWIVKERVETHDRGAGRSVEMCDESVGVEVSVCETGSNTEESVSDLALLTTNL
-NLKDVRSIGCGDCSVDVTVCAPKQCSSRSVNTEAVVQVEAAVTAAPPTTHQHTSTVWER
AHQCTNTETATLVESCTNTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVNSSTKTRSVGVG
TVLSGSLGFDKPSAVKTKEAGVGQINIHDNYLVGLKMRTIACGPPHGSQLSGGPMGSRRS
VGVGDEPVEEFLE--GPQTQAPSGMVTGLDHYIERVQKLLTEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSISSVMKSASPEELRNPDFQKTSLGKT--TGNNLDYT--CK-C
GGL-QSGGL-LSTQLSW----------PVQELGTT-EG------KPKNSQDGFPSQESVP
ALVNLTDDQIAAG--LYVCT-NNENTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEEE-----EEEEDDTRGMAEGHHAVNIEGF
KSTRVD-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLQDNDGSTALSIALDAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

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-----------------------------------------------MVEGHHAVNIEGF
KSARVD-HEMQVQACQPE------------KMLSACNLLKNNINDPKSLTSKYM------
-----------------MFYLNTLQHEWFLVFSQKSAVPAMVGDYTAAFEAVS

PF12796 // ENSGT00530000063448_3_Domain_1 (1254, 1335)

PDVLCYI
INMANAKGNTALHYSMAHSNFGIIKLLLDADVCNVDHQNKAGYTPIMLAALKAVEAEKDM
WIVEELFGCGDMNT

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQVGQMA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LILAVSHGWTDMLKGLLACGADINIQGEKGSTALM-C
DSEHGHAEIIKLL--------HLEDNDSSTALSIALEAGHKDIAVLLYAHVNFAKAQSLS
TPRLGRKMSPGPTHRGSFD-

-------MAHPT--KV-NGC--------ASGTANDVLNGDHGKEQRDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRRKAAVPCTDA-KAT---ASQQAVWTSTES-LSSSNS
DDN-KQCPGFLPARSQVTS--TPISR-PPAPLETSPSFLTIPENRQLPPPSPQLPSHNLH
VTKTLMETRRRLEQERVTMQVTP--GDFRRPRLASFGGMGSTSSLPSYMSSGNHN-PTMH
QLQNGYQGNGDYGGCIPAAAATSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAMSQHDACGVRKRSYSAGNAS
QLDQLSRAPR-S-GGELYIDYDEGE-MESAEQSSQRIKEFRQLTADMQALERKIQDSSGE
AS-WXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXX
XXXXXXXXXXXX-XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXX--X-X
XGL-QPGP--L-GAPTA----------PDQDLGTP-GERP------FSSRSAFTTQEMSP
SPVNLTDDQIAAG--LYAGA-NNENTLKSIMKK-DGSKDSNG--TKKNLQFVGINGGXXX
XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX----X-XXX-XXXXXXXXXXXXXXXXX
XXXXXX-XXXXXXXXXXXXXXXXXXYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVAAMVGDYITAFAAISPEVLRYV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAERDM
RVVEELFACGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENRQLPPPSPQLPKHNVH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAMH
QLQNGYQGNGDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQHNVCGVRKRSYSAGNAS
QLEQLSRARR-N-GGELYIDYEEEE-METAEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSCKDAAVGTLIEMRNCGVSV
TEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVETHDRCAGRSVEMCDRSVSVEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEVAIMAVPRTADQDTSTDLEQ
VHRFTNTETAALIESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGVKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENP-QPQAPPGVMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNYLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VSSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNTINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVDAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC--------ASGKADDVLNGDHDKGQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1253)

KPSVPCPET-RVT---AGQQGVWTSTES-LSSSNS
DDN-KQCPGFLLARGQATS--TPVPR-PPAPLETSPTFLPIPENRQLPPPSPQFPKHNLH
VTKTLMETRRRLEQERVTMQMMP--GEFRRPRLASFGGMGSTSSLPSFMGSGNYS--AAI
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRAASQSDTCGVRKRSYSAGNAS
QLAQLSRARQR-SGGELYIDYEE-EEMESVEQSTQRIREFRQLTADMQALEQKIQDSSCE
AS-LVLRENG-QCPPQECRSVAVGGNENMNDIVVYQQSSRAYKDAAVGTVTEVRDSSIGV
TEAMLGVTTEADKEIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVTAQPLAFSKLVEAVVSTRDQVVGSHVDLVDTCVGTSVQTSSVGISCRSECKNRAA
GPELPMNRWIVKERVETHDRCTGRSVATCDKCVGVEVSVCETGSNTEASVSDLTLLKTNL
-NLKDVRSIGCGDCSVDVTVCSPKEYASRGVNTEVVGQVEAAIMAAPLTTNQHTNTVLEQ
ASQSTNTETATLVDSCTSTSLSTSDKQTSTQTVEVRTVAIGEGRVKDVNSSTKMRSVGVG
TLLSGSSGFDKPSAVKTKELGVGQINVHDNYLVGLKMRTIACGPPQ---LTVGLTGSRRS
VGVGDEPVGELLE--DPQPQAPSGMVTSLDHYIERVQKLLAEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASTEELK--NFQKTNLGKI--AGNNLECT--CK-C
GGL-QSGGL-PSTQTSR----------PEREVGTA-EE------TPASSRETFPSQESTL
PSVNLTDDQIASG--LYVCA-NNENTLKSIMKKRDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPAEEEE-----EEEDEDTRGMAEGHHAVNMEGF
KAARVD-HEMQVQECEPEKVEIRERYELSEKMLSACNLLKSNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFEAV

PF12796 // ENSGT00530000063448_3_Domain_1 (1253, 1335)

SPDVLHYV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKLSPGPTHRGSFD-

------------------------------------INGEDEKERRDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKKRKAIPASTGT-KNS---GGHCSGWTSTES-LSSSNS
DEN-K--QSFLAARSQVTS--SVAVR-PLVSFEASPSYLTVPESKQLPPPSPQLPRHNLH
VTKTLMETRRRLEQER-MMQVTP--GDVRRPRLSSFGGMGSTSSLPSFVGSGGYS-HLSQ
QLQNGYQGNGDYGAC-----FSSSLGSSIRHSPMSSGISTPVTNVSPVHLQHIREQMAVA
LKRLKELEEQVKTIPVLQVKISVLQEEKRHMMAELKTQRKPSQNETYGFRKRSYSAGNAE
QWEHLSQGRR---GGELYIDCED--EMDSGEQSSQRIEEFRQLTAEMQALEKKIQDSNYE
VP-SNLRANR-ESLTKERRSVAVGTDENINDVVIYNRSSRQRREVAVGTEKEMRESGVGV
TEAMLGLSTEVEKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVVSRTVEAVVPTRDQMVGDHVSVADSSVGNHLQMSSIGTSCRPTVRST--
--------------AEVRDQCTGRHVELYDKQVGVETSVCETGVNTEESVGDLSLCRTAQ
-E--ETRSVGCGDCSVNVIVHAPKECVSRETATEAVSRAEAMVMAMPSS--QHTSTALEM
VSRCTSTEALVLADCGTNTVPSSHDKQTNTVSVETRTVAVGDGRVKDIHASAKTRSVGVG
TLYSSHPDFEKPSAIKTKDCGVGQININENYLVGLKMRSIACGPPPLVV----VPAGTRS
IGVGGEPVCESVSGLLESPLPPPELRTGLDHYIERVQKLLQEQQMLLA-------EXFGE
PHSQIGSLNSQLISTLTSINSVMKYASTEELRSLDLQKQCAERNTASGLTFTCICAGKES
I-----VPLVDQMTKRNF---------SK------IGKGQP-----SISMSSAQIQDKTL
AAINLTDDQLASG--LYVCS-NNENTLKSIMKKRDGKKDLSN--TKKNLQFVGINGGYET
TSSDDSSSEESSS-SDSEEESEGHAYPHGHGA----------------------------
------EEEEDPVECEAEEVEIRERYELSEKMLSACHLLKNNIDDPKALTNKDV------
-----------------RFCLNTIQHEWFRVSSQKSAVPEMVGDYITAFEEISPAVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1304)

NGNTALHYSVSHSNFEIVKLLLDANVCNVNHQN----

ENSGT00530000063448_3_Linker_1_2 (1304, 1305)

N

PF00023 // ENSGT00530000063448_3_Domain_2 (1305, 1337)

PIMLAALAAVEAEKDM
RIVEELFSCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKALLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGTLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFSKTQSPG
TPRLSRKTSPGPTHRATFE-

---------LSNATQP-SGW--------STVKADDVLNGDHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSVPCPEP-RAT---P---GVWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISR-LPAPLETSPPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHN-PAMH
QVQNGYQGNGDYGGYAPAIATTSSMGSSIRHSPLSSGVSTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAVSQNDACGMRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-LELRENG-E-----CRSVAVGAEENMNDVVVYHRSSRSYKDAAVGTVIEMRNCGITV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDWEMTKLKQELQAAGSRKK
VDKAMVAQPLVFSKMVEAVVQTRDQMVGSHVDVVDTCVGTSVQTNSVGISCQPECKEKVS
GPELPMNWWIVKERVEMHDRCTGRSVDSCDKSVGMEVSVCETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKEYTSRSVSTEAVGQLEAAVMAVPHTTDQHTSMVLEQ
VNQSTNTETATLVESCTNTSLSTSDKQTSTQAVEMRTVAIGEGRVKDVNSSTKMRSIGVG
TLLSGSSGFDRPSAVKTKESGVGQININDNYLVGVKMRTIACGPPQ---LAVGLVASRRS
VGVGDEPVGELL-ENL-QPQPPSGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASAEELRNPDFQKTNLGK--ITGSNVEYTC--K-C
GGL-QSGGP-LSTQRSW----------PEQEVGTT-EGKA------LNHQDTFPTEQCTL
SPVNLTDDQIAAG--FYVCT-NNESTLKSIMKKKDGNKDANG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEEE----E-EEEEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYIAAFEAISPEVLRYV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFACGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAPSPG
TPRLGRKTSPGPTHRGSFD-

-------MAHTT--KV-NGC--------ASGKAEGVLNGNHDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPSVPCPDS-RTA---PGQQGVWTSTES-LSSSNS
DDN-KQCPPFLLSRSQVTS--TPTPR-PPAPLETSPTSLTVPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGLGSTGSLSSFLGSGNHN-PTVH
PLQNGYQGNGDYGGYVPAAATTSSMGSSVRHSPLSSGISTPVTNVSPVHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAPAQNDIGGIRPRSYSAGNAS
QLEELSRARR-G-GGELYIDD-EEE-MASVEQSAHSIREFRQLAADMRALEQKICDSGGE
AS-PGPREGS-EYRSVAVGGDERMDHVVVYRRGPGTCRDAAVGTVAETRSCGVGVTEAML
GVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKKVDKAV
MAQPLVCSKMVEAVVPTRDQMAGRHVDVADAGVGTSVQTWSVAVSCQPACETRAMGPELP
MHRWVIKERVETRDQGAGRLVEMSDQSVGVEISVCETGSNTEESVNDLSLLKTNLHLKEV
-RSIGCGDCSIDVTVCPPKECTSRGLSTETVPQ---VEAAVMAVPATTSRH-TSTVWEQV
DQSTNTEMATLVDSCTNTSLSTLDKQTS-TQTVETRTVAIGEGRVKDVNSSTKMRSIGVG
TVLSGSSEFDRPSAVKTKESGVGQINIQDNYLVGLKMRTIACGPPQ---LTLGLAASRRS
VGVGDEPVGESA-EDP-QPQAPSGTMNGLDHYIERVQKLLAEQQKLLAENYSELAEAFGE
PHSQMGSLNSQLISALSSINSVMKSASAEELRSSELPKMSLGQ--VTGSSLEYAC--K-C
GGL-QAGAP-FHTQTSQ----------HEQAVGTM-EGRP------LGGQDAFPPQESTL
CPVNLTDDQIAAS--LYVCT-NSESTLKSIMKKKDSNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVSEYPPEDEEE----E-EEDEDTRGMAEGHHAVNVEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRASSQKSASPAMVGDYLAAFRAVSPDVLRHV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRSSFD-

-------MAHTT--KV-NGC--------ASGKADDVFMGDHDRGQKGPNFVETPYGYQLD
LDFLKYVDDIQKGNTIKKVNIQKRRKPSVPRPET-RAA---PGHQGVWTSTES-LSSSSS
DGN-KQ-----LAQSEVTS--APVPR-PPAPLETSPTFLTIPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGVGSTSSLSSFMGSGNHN-PAMQ
QHQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKDHRAASQNDVCGVRKRSYSAGNAS
QLEHLSRTQR-S-GGELYIDYEEGE-MEGAEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG-QCRRRECQSVAVGADENMDSIVVHHRGARSCKDVAVGTVTATRNSGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMMAQPLVFSKVVEAVIPTRDQIAGSHVDVVDTCVGTCVQTNSVGISCQPDRENKVV
GPELPMNWWIVKERVEMHDRCTGRSVGTCDKSVGVDISVCETGSNTEESVSDLTLLKTNL
-NLKEVRSIGCGDCSVDVIVCSPRECISRSVNTEAVSQVEAAVMAVPRTTSQHSSTVLEQ
VSQFTNTETATLTESCTNTSLSTMDKHTSTRTVEMRTVAVGEGRVKDVS-SAKMRSVGVG
TVLSGASGFDRPSSVKTKESGVGHISINDNCLVGLKMRTIACGPPQ---LTVGPNGSRRS
VGVGDEPVGEFV-ESP-QPQAPSRMVTGLDHYIERVQKLLAEQQALLAENYSELAEAFGE
PHSQIGSLNSQLINALSSINSVVKSASAEELR-PDFLKTSLGK--VTGSNLEYTC--K-C
GSL-QSGGP-LNSQTSR----------HEQEVGTT-EGKP------ISSQDTFPTQESTL
SPVNLTDDQIAAG--LYVCT-NNESTLKSIMKKKDANKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVPEYPPEEVED----E-EEDQDTQGMAEGHHAVNVEGL
TSSRVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYIAAFEAISPDVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCNVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFACGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1372)

D

PF00023 // ENSGT00530000063448_3_Domain_4 (1372, 1406)

EGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLED

ENSGT00530000063448_3_Linker_4_5 (1406, 1407)

N

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

------------------MAYPANTNGSAAEKEEVSINGEDEKERKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIRKRRKAVPASVGT-KNS---GGQCSGWTSTES-LSSSNS
DEN-K--QSL-ATRCQVTL--PVPAK-PSVSFEVSPTYLTVPENKQLPPPSPQPPRHNLL
VTKTLMETRRRLEQER-MMQGTP--GDVRRPRLSSFGGMGSTSSLPSFVGSSGYS-QVSQ
HLQNGYQGNGDYGAC-----FSSSLGSSIRHSPMSSGISTPVTNVSPVHLQHIREQMAVA
LKRLKELEEQVKTIPVLQVKISVLHEEKKHMMAELKNHRKATQNETYGFRKR--------
------------------------------------------------------------
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--------------------

---------MAHTTKV-NGC--------VSARTDDVLNGDHDNEQKDPYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRRKPPVPCPES-RAT---PAHPGVWTSTES-LSSSNS
DDN-KQCSSFLLARSQVTS--TPTAR-PPAPLETSPTFLTVPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVAMQVTP--GEFRRPRLASFGGMGSTSSLPSFMGCGNHN-PAMY
QLQNGYQGNGDYGGYVPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQSDVGGMRKRSYSAGNAS
QLDQLSRARR-S-GGELYIDYEEEEMMESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
DS-SVLRENG-QCQPPECRSVAVGADESMSDVVVYHRGSRSYKDAAVGTVTETRNSGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVTAQPLVFSKMVEAVVQTRDQMVGGHMDLVDTCVGTSVPTNSVGTSCQPECKSRVV
GPELPMNRWIVRERVEMHDRCTGRSVETRDQSVGVEVSICETGSNTEESMNDLTLLKTNV
-NLTDVRSIGCGDCSVDVTVCSPKQCTTRSVNTEAVGQAEAAVMAVPPTMDQHTSTLWEQ
VSQATNTETAPLVESCTNTSLSTSDKQTSTHPVATRTVAIGEGLVKDINSSTKMRSIGVG
TLLSGSSGFDRPSAAKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTAGLMASRRS
VGVGDEPVGESXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXTEELRNADFQKTSLGE--VTGNGLGCTC--K-C
GGL-TSGGP-LSSQTSQ----------PEHEAGTT-EGKP------RSRQDAVASQESAL
SPVNLTDDQIAAG--LYVCA-GNESTLKSIMKKKDGNKDANG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVSEYPPEEEEEE-----EEDEDIRGMAQGHHAVNIEGF
KSIRVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPALVGDYLAAFEAVSPEVLRYV
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1297)

NGNTALHYSVSHSNFEIVKLLLDADVCDVD

ENSGT00530000063448_3_Linker_1_2 (1297, 1301)

HQNK

PF00023 // ENSGT00530000063448_3_Domain_2 (1301, 1337)

AGYTPIMLAALAAVEAEKDM
RVVEELFSCGDVNAKA

ENSGT00530000063448_3_Linker_2_3 (1337, 1339)

SQ

PF00023 // ENSGT00530000063448_3_Domain_3 (1339, 1371)

AGQTALML-VSHGRIDMVKGL-ACGADVIIKDDEGSTT-M-C
ASEHHV---IVKLLLQPGCNHL--EN

PF00023 // ENSGT00530000063448_3_Domain_5 (1407, 1436)

DGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSLD-

--------------ML-HTC--------NPRKADDVLNGDHDKGQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1255)

KPSVPCPET-RVT---PGQQDVWTSTES-LSSSNS
DDN-KQCPSFLLARGQVTS--TPAPR-PPPPLETSPTFLPIPENRQLPPPSPQFPKHNFH
VTKTLMETRRRLEQERVTMQMTP--AEFRRPRLASFGGMGSTSSLPSFMGSGNYS--AAI
QLQNGYQGNGDYGSYAPVAATTSSMGSSIRHSPLSSGVSTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRTASQNDLCGVRKRSYSAGNAS
QLDQLSRAR-R-SGGELYIDYEE-EEMESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS---------LCPAQECRSVAVGGNENMHDIVVYQRSSRAFKDTGVGTVTEMRDSSVGV
TEAMLGVTTEADKEIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAVMAQPVVFSKLVEAVMSTRDQMVGSHVDLVDTCVGTSVQTSSVGISCQSEHKNQAV
GPELPMNRWIVKERVEMHNRCTGRSVETCDKHVGVEVSVCETGSNTEASVSDLTLLKTNL
-NLKDVRSIGCGDCSIHVTVCSPKEYISHGVNTEVVGQVEAAVMAAPLTTNQHTSTLLEQ
MSQSTNTETATLVDSCTSTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVTSSTKMRSVGVG
TLLSGTSEFDKPSAVKTKELGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLTGSRRS
VGVGDEPVGELLE--ESQPQAPTGMVTSLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASAEEFKNTDFQKISVGKI--AGNNLEYT--CK-C
GGL-QSGEL-S-----Q----------SEREVGTS-EG------SPMSSQMTFPSQESTL
APVNLTDDQIASG--LYVCA-NNENTLKSIMKKRDGNKDATG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVTEYPPEEEEEE----EEENEDTRGMPAKGLS--TEGL
T-----------------------------------------------AALCWQ------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYLAAFRAVSP

PF12796 // ENSGT00530000063448_3_Domain_1 (1255, 1335)

GVLRYV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAPSPG
TPRLGRKMSPGPAHRGSFD-

---------MAYTTKV-NGS--------ASGKADDILNGDQDKEPKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQYPDFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSQARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCVGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLTDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSTVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLRYTC--K-C
GGL-QSGSP-LSSQTSR----------PEQEVGTS-EGKP------VSSLDAFPTQEDTL
SPVNLTDDQIATG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

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-----------------------------------------------LVQGHDLLKGV--
------------------------GF-EMKIMLSACNLLKNNTNDPKALTSKGV------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPAHRGSYD-

---------MAYTTKV-NGC--------AAEKADGVLNGDHNKEKKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEV-RAI---PGHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFAVSENRQLLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVTMQMAP--GDFRRPRLASFGGMGSTSSLPSFVGSANHS-SAIH
QLQNGYQGNGDYNSYVPAAPTTSSMGSSVRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKSQRASSQNEACGVRKRSYSAGNAS
QLELLARARR--GGGELYIDYEE-EEMESVEQSTQRIQEFRQLTADMQALERKIQDSSCE
VA-SELRENG-QCPSRECKSVAVGSDENMNDVVVYHRDLRPCKDTAVGTVTETRNVGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEALVPTRDQMVGSHVDTRESCVGTSVQTSSVGTSCHPDCKNQVV
GSELPMNWWVVKERVAMHDQCVGRSVETCDRSVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCFPKECTSRSMNTEAVGQEEAAVMAVPHTTDQHTSTNLER
VDQCTNTEAATLVESCTNTLLSTMDKQTSTQTVEMRTVAIGEGRVRDINPSTKTRSVGVG
TVLSGNSEFDRPCAVKTKESGVGQINIQDNYLVGLKMRTIACGPPQ---LTVGLMGSRRS
VGVGNEPVGELPEE-SPQPRVASGMVTGLDHYIERVQRLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNSDFQKASLGKT--TGNHLEYT--CK-C
GGL-RSGGL-LNVQPSQ----------PEVEAETA-EG------KHSRGHEQFPMQGSTL
PPVNLTDDQIATG--LYVCP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGINGGYET
TSSDESSSDGSSS-SESDDECDTIGYPPEEEEE----EEEKDHDTRGMAEGHHAVNIEGF
KSARVE-DEVQVPECEPEKEEIRERYELSEKMLSACNLLKYNIKDPKALASKDM------
-----------------RICLNTLQHDWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1429)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHLNFSKAQSPS
TPRLGRKTSPGPTHRGSFD-

---------MAYTTKV-NGR--------APEKADGILNGDPNKEKKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEV-RAI---PGHQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFAISENRQLLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHS-SAMH
QLQNGYQGNGDYSNYVPAAPTTSSMGSSVRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLAAQLKNQRAASQNEACGVRKRSYSAGNAS
QMELLSRARR--GGGELYIDYEE-EEMESVEQSTQRIQEFRQLTADMQALEQKIQDSSCE
VA-PELRENG-QYPSRECKSVAVGSDENMNDVVVYHRDFRPCKDTAVGTVTETRNFGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEALVPTRDQMVGSHVDTRESCVGTSVQTSSVGTSCHPDYKNQVV
GPELPMNWWVVKERVAMHDQCVGRSVETCDRSVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVVVCFPKECISRSMNTEAVGREEAAVMAVPHTTDQHTSTNLER
VDQCTNTEAATLVESCTNTFLHTLDKQTSTQTVEMRTVAIGEGLVRDINPSTKTRSVGVG
TVLSGNSEFDKPCAVKTKESGVGQINIQDNYLVGLKMRTIACGPPP---LTVGLMGNRRS
VGVGNEPVGELLEE-SPQPRVASGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKASLGKI--TGNHLECTCTCK-C
RGL-WSGGR-VNAQPPQ----------PEVEAETA-EV------RHTQGLEQFPTQGSTL
PPVNLTDDQIATG--LYVCP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGINGGYET
TSSDESSSDGSSS-SESDDECDTIGYPPEEEEEEEEEEEEKDHDTRGMAEGHHAVNIEGF
KSARVE-DEVQVPECEPEKEEIRERYELSEKMLSACNLLKHNIKDHKALASKDM------
-----------------RICLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHLNFSKTQSPS
TPRLGRKTSPGPTHRGSFD-

---------MAYTTKV-NGY--------GADKTDDVLNGDHNKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSGPCPEV-KAT---PAHQGVWTSTES-LSSSNS
DDS-KQCPSFHLARSHVTS--TPIPR-PPAPLETSPTFAIPESRQLLPPPSPQPPKHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSYMGSGNHN-SAMH
QLQNGYQGNGDYGSYVPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNEACGVRKRSYSAGNAS
QLELLSRTRR--GGGELYIDYEEEEEMESVQQSTQRIKEFRQLTADMQALEQKIQDSSCE
AA-SELRENG-QCPSRECKSVAVGSDENMNDIVVYHRDFRTCKDTAVGTVIETRNFGTSV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEALVPTRDQMVGSHVDTTDSCVGTSLQTSSVGISCQPDRKNQVA
GPELPMNWWVVKERVEMHDQCVGKSVETCDQSVGVEVSICETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCAPKECASRSMNTEAVSQEEAAIMAVPDTTNQHTSTTLEQ
VDQCTNTEAATLVESCTNTFLSTLDKQTSTQTVEMRTVAIGEGRVKDINPSTKTRSVGVG
TVLSGNSEFDKPSAVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLMGGRRS
VGVGSEPVGDLMEE-APQPPLASGMVTGLDHYIERVQKLLAEQQALLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKSASMEELRHPDFQKTRLGKI--TGNH------CK-C
GGL-RSGGL-LNVPTAQ----------PEQETGMA-EG------KLVRGRDQFPTQGNT-
PPVNLTDDQIATG--LYVCP-NNENTLKSIMKKSDGNKDPNG-GAKKNLQFIGINGGYET
TSSDDSSSDGSSS-SESDDECDTIEYPPEEEEE-----EEEDDDTRGMAEGQHAVNIEGF
KSARVE-DERQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPEVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDNEGSTALM-C
ASEHGHVEIVKLLLAQPGCNSQLEDNDGSSALSIALDAGHKDIALLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAYTTKV-NGC----------ENADGVLNGDRNKEKKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGFQLD
LDFVKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSGPCAEV-RAI---PGPQGVWTSTES-LSSSNS
DDS-KQCPSFLLARSHVTS--TPIPR-PPAPLETSPTFAISENRQLLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVTMQMAP--GEFRRPRLASFGGMGSTSSLPSFMGSGNHS-SAMH
QLQNGYQGNGDYSSYVPAVPTTSSMGSSVRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNEACGVRKRSYSAGNAS
QLELLSRARR--GGGELYIDYEE-EEMESVEQSTQRIREFRQLTADMQALEQKIQDSSCE
AT-PELRENG-QCASRERKSVAVGSDENMNDIVVYHRDFRSRKDTAVGTVTETRNFGISV
TEAMLGVITEADKEIELQQQTIEALKEKIYRLEVQLKETTHDQEMTKLKQELQAAGSRKK
VDKAIMAQPLVFSKLVEALVPTREQMVGSHVDTMDSCVGTSVQTSSVGTSCHPDRKNQVV
GPELPMNWWVVKERVGTHDRCVGRSVETCNRSVGVEVSVCETGSNTEASGSDLTLLKTNL
-NLKDVRSIGCGDCSVDVIVCLPKECTSRSMNTEAVGQGEAAVMAVPHTTDQHTSTNLER
VDQGTNTEVTTLVESCTNTLLSTLDKQTSTQNVEMRTVAIGEGRVRDINPSTKTRSVGVG
TVLSGSSDFDKPCAVKTKESGVGQINIHDNYLVGLKMRTIACGPPQ---LTVGLIGSRRS
VGVGNEPVGDLLED-PLQPQVPSGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKSSLGKI--AGNHLECT--CK-C
GGL-RSGGL-VNVQTSQ----------PEVETETT-E--------GKRGCEQFLTQGNTL
PPVNLTDDQIATG--LYVCP-NNENTLKSIMKKSDGNKDSNG--AKKNLQFIGVNGGYET
TSSDDSSSGGSSS-SESDDECDTNGYPPEEEEEEE--EEEEDHDTRGMAEGRHAVNIEGF
QSARVE-DEVQVPECEPEKEEIRERYELSEKMLSACSLLKYNINDPKALASKDM------
-----------------RICLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRYI
INMADGNGNTALHYSVSHSNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCSGHLEDNDGSTALSIALEAGHKDIAVLLYAHLNFSKAQSPS
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPDFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSQARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLTEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECVSRGVNTEAVGQVEAAVMAVPRTTDQDTSTDLEQ
VHQFTNTEMATLIDSCTNTCLSTSDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VNSLDAFPTQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

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-----------------------GQVQWLTP--------------------VIP------
----------TLWEADAGGSHEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

-----------------------------SCKKADVVNGDHDKEQKG

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYCVETPYGYQLD
LDFVKYVDDIQKGNTIRKANIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1261)

KPPVPCPDS-RTA---PGQPSFWTSTES-LSSSNS
DDN-KQSPNFLLGRSLVTS--TPVPR-PPAPLETSPTFLTVPESRQLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVTMQMTP--GEFRRPRLASFGGMGSTSSLPSFMGSGSHH-PAL-
QLQNGYQGNGDYGSYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQQAAWQDDVCGVRKRSYSAGNAS
QLQLLSRARR-G-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AA-SEPRENG-QCRPPERRSVAVGGDGNMNDIVVYQRSSRPCKDAAVGTVTETRNLGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKLVEATVQTRDQVVGSHVSTVDTCVGTALQTNSIGISCQPECRSQMV
GLELPMNWWIVKERVEMHDRCTGRSVETRDQSVGVEVSVCETGSNTETSGSDLKSLQTNL
-HLKDVRSIGCGDCSVHVTVCSPKEYTSRSVATEAVGQVEVAVMAAPHTTSQHTSTSLGQ
VDQSTSTDPATLVDSCTNTFLSTWDKQTNTQIVEMRTVAVGEGRVKDINPSTKTRSVGVG
TMLSGSSELDRPSTVKTRESGVGQINIHDNYLVGLKMRNIACGSPP---LTVGPTGSRRS
VGVGDEPIGELLLGGP-EPQVASGMMTGLDHYIERVQKLLAEQQTLLAANYSELAEAFGE
PYSQIGSLNSQLMSTLSSINSVMKSASTEELRNPDFQKTNLGK--VTGNNLEYSC--K-C
GGL-QSGGL-VSMPTSQ----------PEYKVEAT-EEKP------LSSQNSFLSQENML
APVNLTDDQIATG--LYVCT-NNENTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEEEE---EEEDEEDTQGMAEGHHAINNEGF
KSARVE-DETQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQQEWFRVSSQKSAVPAMVGDYIAAFDAVSPAVLRYI

PF13637 // ENSGT00530000063448_3_Domain_1 (1261, 1288)

INMADGNGNTALHYSVSHSNFEIVKLL

ENSGT00530000063448_3_Linker_1_3 (1288, 1313)

LDADVCNVDHQNKAGYTPIMLAALA

PF12796 // ENSGT00530000063448_3_Domain_3 (1313, 1400)

AVEAEKDM
RVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGC

PF12796 // ENSGT00530000063448_3_Domain_4 (1313, 1400)

AVEAEKDMRVVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-CASEHGHVEIVKLLLAQPGCNGHLEDNVSIVS-SSTLPVGHLPDCARLYAHS------AQG
TPRLGRKTSPSPTHRGSFD-

------------------------------------------------------------
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------------------------------------------------------------
--------------------------------------------------------VGVG
TMLSSHPGFEKPSAIKTKDCGIGQISVYENYLVGLKMRSIACGPPPLPV----VPAGTRS
IGVGGESVCDPVSGQPESPLPPSELRTGLDHYIERVQKLLQEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSINSVMKYASTEELRSLDLQKQCMERSTPSGLQISCLLGSLLV
W-----KPLCSP--------------------PQRSTEQGIVVECPLGILKSFSSQDKAL
TPINLTDDQLASG--LYVCT-NNENTLKSIMKKRDGKKELSN--TKKNLQFVGINGGYET
TSSDDSSSEESSS-SDSEEECESHEYPCHQHTEEKQ-------PSPH----------AAE
VCAMGAEKDSPLPECEAEEVEIRERYELSEKMLSACNLLRNNIDDPKALTNKDV------
-----------------RFCLNTIQHEWFRVSSQKSALPEMVGDYITAFEEISPAVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1299)

NGNTALHYSVSHSNFEIVKLLLDANVCNVNHQNKAGYTPIMLAALAAVEAEKDM
RIVEELFSCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKALLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNSTLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKTQSPG
TPRLSRRTSPGPTHRATFE-

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-----------LGNKLLLGDGCSLNRLFFADVCNVDHQNKA

PF00023 // ENSGT00530000063448_3_Domain_2 (1302, 1335)

GYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_2_4 (1335, 1359)

KASQAGQTALMLAVSHGRIDMVKG

PF13857 // ENSGT00530000063448_3_Domain_4 (1359, 1415)

LLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFE-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSPARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGTLIEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTEMATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGHVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VSSLDAFPTQEDTL
SSVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-------EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

------------HEKK-FFF-------FFAEKSQSVLNGNSEKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKVNIQKRQ

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KPVPQHTGT-KDT---HGQLDIWASTES-LSSSNS
DDN-KHCPSFLTVRSQVTA--PPATR-QPDPPELSPTFLAIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQEKVNMQVGP--GEFRRPRLASFGGLGSTGSLPSFMGSGNRN-PAAH
QLQNGYQGIGEYSIYTTA-GTTSSVGSSLRHSPMSSGISTPVTNVSPLHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRSPSQNDTCGVRQRSYSAGNAS
QLQQLSWVKR-GDRGELYIDCEEEE-MESIEQSTKRIKEFRQLTAEMQALEKKIQDSSYG
AS-LEIRENR-ECVSKECKSVAVGADDNMHDIVLYHKSSRPCREAAVGTEAETRDSGVGV
TEAMLGITTEADKEIELQQQTIEALKDKIFRLEVQLKETTYDREMTKLKQELQAAGSRKK
VDKASMAQPLVLSRMVEAVVQTRDQTVDSHVDMMDACVGTELQTHSIGISCKPDWENKIV
GPELPMNWWIVKEHVEMCDQCVGRSVKMCDKNVGMETSICVTDSNTKKSLVDQTPCKAQL
-NINEVRSIGCGDCSVNVTVCSPKEYNSQSVNTESIFLVNSSVMAVPQTMNQHTTTVLEQ
VNQFTNTEMRSLMDSSTNTFLSTFDKQTNTRTVDVRTVAVGEGRVKDVNASSKTRSIGVG
TLLSSDSGFDKPSAVKTKDSGVGQININENYLVGLKLRNIACGPPQ---LSVGLAASRRS
IGVGDEPVGELV-ENP-LNQPPSEIMTGLDHYIELVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLMSTLSSINSVMKYTNPEELNNTDFQRQKMAGKKLKAKLSQFKC--QVC
VGI-LSFSE-KTVRTIW----------PQN--------RV------GSDQESFLSQ-DKT
SPVNLTDDQIAAG--LYVCA-NNDTTLKSIMKK-EGKKESNS--TKKNLQFVGINGGYET
TSSDDSSSDETSS-SESDDECDVLE------------E-EEVEDTQGMAEGHHAVNVESF
RSIGVEENDIKVPESKAEKVEIRERYELNEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTIQHEWFRVSSQKAAIPDMVGDYIAAFEEVSPEVLQYI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1296)

NGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKGLLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1396)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGTLEDNDGSTALSIALEAGHKDIAVLLYAHVNFSKPQSPG
TPRLGRKTSPGPTHRGSFD-

------------------------------------------------------------
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-----METRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTGSLPSFVGSGNHS-SAMH
QLQNGYQGNGDYGGYAPAAPTSSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDLCGVRKRSYSAGNTS
QLEQLSRARR-S-GGELYIDYEEEE-MESVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SKLRENG------ECRSVAVGAEENMNDIVVYHRGSRSFKDAAVGTVIEMRNYGVNV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGPRKK
VDRATMAQPLVFSKVVEAVAQTRDQTVGSHTVLVDTCVGTSVQTNSVGISCQPECKNKVV
GPELPMNWWIVKERVETHDQCTGKSVEMCDKSMSVEVSVCETGSNTEESVNDLTLLKTNL
-NIKEVRSIGCGDCSVDVTVCSPKEYTSQGVNTEALGQVEAAIMAVPHTTDQDTSTDLEQ
VHQFTNTNTATLVESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDVNSSAKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENP-QPQVPPGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNNLGYTC--K-C
GGL-QSESP-LSSQTAQ----------PEQEVGTS-EGKP------ISSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEEE----E-EEDEDTRGMAQGHHAINIDGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAYPANI-SGS--------TSEKEESVLSGEDDKEHKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKKR

ENSGT00530000063448_3_Linker_0_1 (86, 1267)

KLVPTFTG---TK---NCQYSGWTSTES-LSSSNS
DET-KH-PSF-AARNQVAS--SGTVR-PSVSLEGSPAFLTIPESSQLPPPSPQLPRHNLH
VTKTLMETRRRLEQERVIMQVTP--GDVRRPRLSSFGGLGSASSLPSFVGSSGHN-QTSQ
QLQNGYQGNGDYNVYLA-----SSVGSSIRHSPLSSGISTPVTNVSPVHLQHIREQMAVA
LKRLKELEEQVKTIPVLQVKISVLQEEKRQMMAELKTQRKPNQNDSSSFRKRSYSAGNAE
QWGHLSQVKR---GGELYIDCEE--DMGSAEQNLQRAEEFRQLTFEMQALERKIQDSSYE
IP-SNLRMNR-EGLTKESRSVAVGADENMNDVVIYNRSSRPCAEVAVGTEKETRDSWVGV
TERMLGITTEAEKEIELQQQTIEALKGKIYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKALMAQPLVFSTMVEAVVQTRDQMVGNXX-----------XXREIGISCKPDLQSTAV
GPEQLMSQWLVKEKADMHDQCTGRSIEMCDKNVSTEKSVCETGVNTEESVDNLSLCKTEA
-EIKEARSIGCGDCSVNVTVCPSKECVSRSTNTEAVHKVESAVMAVPHTATQQTSTVLIM
VNQFTNTETASLMDSSTNTMLSTYDKQTNTVNVEMRTVAVGDGRVKDINASAKTRSVGVG
TLLSSDSNFEKPSVIKTKDCGVGQINIHENYLVGLKMRNIACGAPPLSV----VPASTRS
IGVGDEPAYESVGILVESPFPPPEMKTGLDHYIERVQKLLQEQQMLLAENYSELAEAFGE
PHSQIGSLNSQLINTLSSINSVMKYASTEELRNLDIQKQCMDRSSTTDDNLEYIPH----
GQL-ASAHLTSSSRTLK----------SGQETGTIQEQKMIATVERGQGTKSLSSQNNTI
PPFNLTDDQLASG--LYVCA-NNESTLKSIMKKRDGEKDFNS--TKKNLQFVGINGGYET
TSSDDSSSEESSS-SESDDECEDNEYSHQEER----------HSLQEMEEGCHMLNAEDV
GCVGVD-EEVQAQEREPEEVEIRERYELSEKMLSACNLLKSNIDDPKALASKDM------
-----------------RFCLNTIQHEWFRVSSQKSAVPAMVGDYIAAFEDVSPTVLRHI
INMADG

PF00023 // ENSGT00530000063448_3_Domain_1 (1267, 1299)

NGNTALHYSVSHSNFEIVKLLLDANVCNVNHQNKAGYTPIMLAALAAVEAVKDM
RIVEELFGCGDVNAKASQA

PF00023 // ENSGT00530000063448_3_Domain_3 (1340, 1371)

GQTALMLAVSHGRIDMVKALLACGADVNIQD

ENSGT00530000063448_3_Linker_3_4 (1371, 1373)

DE

PF00023 // ENSGT00530000063448_3_Domain_4 (1373, 1397)

GSTALM-C
ASEHGHVEIVKLLLAQPGCNGTLQDSDGSTALSIALEAGHKDIAVLLYAHVNFSKPQSPS
TPRLSRKTSPGPTHKATFD-

---------MAHTTKV-NGS--------ASGKADDSLNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVQCPET-RTT---SGQQGVWTSTES-LSSSNS
DDN-KQCPNFLLAGSQVTS--TPISK-PPAPLETSLPFLTIPENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTGSLPSFVGSGNHN-PAMH
QLQNGYQGNGDYGGYAPAAATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNDLCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-METVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSFKDAAVGTVIEMRNYGVNV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQIVGSHTVLVDTCVGTSVQTNSVGISCQPECKNKVM
GPELPMNWWIVKERVETHDQCTGKSVEMCDKSVSVEVSVCETGSNTEESVNDLTLLKTNL
-NIKEVRSIGCGDCSVDVTVCSPKEYTSQGVNTEALGQVEAAVMAVPRTTDQDTSMDLEQ
VHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDVNSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESSVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGEFL-ENP-QPQIPPGMMTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQNTSLGK--ITGNNLGYTC--K-C
GGL-QLGSP-LSSQTSQ----------PEQEVGTS-EGKP------ISSLDTFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--TKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEEE----E-EEDEDTRGMAQGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGS--------ASGKADDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSMPCPEP-RTT---SGQQGIWTSTES-LSSSNS
DDN-KQCPNFLLARSQVTS--TPISK-PPAPLETSLPFLTIPENQQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAIH
QLHNGYQGNGDYGGYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-MESAEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SEFRENG------ECRSVAVGAEENMNDIIVYHRGSRSCKDAAVGSLIEMRNCGVSV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHTDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVEMHDRFAGRSVEMCDKSVSVEVSICETGSNTEESVNDLTLLKTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVGQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIDSCTNTCLSTLDKQTSTQTVETRTVAVGEGRVKDINSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGDDPVGESL-ENS-QPQAPPGMTTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGSNLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------PEQEVGTS-EGKP------VSSLDAFPIQEDTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNRDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-------EEDEDTRGMAEGHHAVNIEGF
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAISPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-

---------MAHTTKV-NGC--------ASGKADDILNGGHDKGKKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSAPCPET-RVT---PGPQGVWTSTES-LSSSNS
DDN-KQCPSFLLARSQVTS--TPGPR-PPPPLETLSTFLPIPENPQLPPPSPQFPKHNLH
VTKTLMETRRRLEQEKVTMQMSP--GEFRRPRLASFGGTGSTSSLPSFIGSGNYS-AAIH
QLQNGYQGNGDYGGYAPVAATASSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKTQRAASQNDLCGVRKRSYSAGNAS
QLEQLSRAQR--SGGELYIDYEE-EEMESVEQSTQRIREFRQLTADMRALEQKIQDSSCE
AS-LVLRENG-QGPPQECRSVAVGGDENMNDIVVYHRGSRACKDATVGTVTEVKDSGVGV
TEAMLGLTTEADREIELQQQTIEALKEKVYRLEVQLKETTHDREMTKLKQELQAAGSRKK
VDKAMTAQPLVFSKLVEAVVPTRDQMVGSHVDLVDTCVGTSVQTSSVGISCQPDCKNRAV
GPELPMNRWIVKERVETHDRCTGRSVETRDECVGVEVSICETGSNTEASVSDLTLLKTNL
-SLKDVRSIGCGDCSVDVTVCLPKQYASRSMNTEAVARVEAATMAAPATMNRHTCTVFEQ
VSQSTNTKPTVLVDCCTNTSLSTLDKQTSTQTVEMRTVAIGEGRVKDVISSTKMRSVGVG
TLLSGNSGFDRPSAVKTKELGVGQINIHDNYLVGLKMRSIACGPPQ---LTVGLTGSRRS
VGVGDKPVGELLE--DSQPLAPSGMVTNLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLTSIHSVMKSASTEELKNADFQKTSLGRI--VGCDLEYT--CM-Y
GDL-L------SAQMSR----------PEHEVGTA-EG------TPMSSQETFPSQESTP
APVNLTDDQVASG--LYICT-NNESTLKSIMKKQDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESYDECDVIEYPPEEE---------ENEDTRGMAEGHHAVNTEGF
KSARVD-HEMQVQECEPEKVEIIERYELSEKMLSACKLLKNNINDPKALTSKDL------
-----------------RFCLNTLQHEWFRVSSQKSAVPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPEVLRHV
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
QVVEELFSCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1429)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLADNDGSTALSIALEAGHGEIAFLLYAHVNFAKAQSPG
TPRLGRKMSPGPTHRGSFD-

---------MAHATKV-NGC--------ASGKTDDVLNGDPDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKKLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPES-RAV---PGQQAVWTSTES-LSSSNS
DDN-RQCPHFLVARSHVTS--TPIPR-PPAPLETSPPFLTVPESRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERVTMQVAP--GEFRRPRLASFGGMGSTSSLSSFMGSGNHN-PAAH
QLQNGYQGNGEYSGYAPAVATTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLASQLKHQRATAQNDACGVRKRSYSAGNAS
QLERLSRARRSSGGGELYIDYEE-DEMERVEQSAQSIREFRQLAADMQALERKIQDSSCE
AS-SGPREDG-E-----CRSVAVGADETMDRVVVYRRGSASRKDAAVGTATESRTCGVGV
TEAMLGVTTEADKEIELQQQTIEALKEKIYRLEVQLKETTHDREMTRLKQELQAAGSRKK
ADKAVTAQPLVLSKMVEAVVATRDQTAGHHVDLADACVGSAVQMHSLGVSCRPRCESRLV
GPELPMNWWIVKERVETHEQGTGRSVETCDKSVGVEISVCETGSNTEESVHDLSLLKTNL
-NLKEVRSIGCGDCSVDVTVCPPKELTSRSVNTEAAGLVEAAVMAVPRTASRHTSTVWEQ
VDRGTNTEVVTLVESCTSTSLSTLDKQTSTQTVEMRTVAVGEGRVKDVNSSTNTRSIGVG
TVLSGTSGFDRPSAVKTRESGVGQININDNYLVGLKMRTIACGPPQ---LTLGLAASRRS
VGVGDGPVGEFAE--SPPPQAPAGMVTGLDHYIERVQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFPRMSLGKV--TGSSLEYP--CK-C
GGL-QSGGP-FNTQTSR----------HEQEAGTT-EG------RPLGGQDAFPSQESAL
SPVNLTDDQIAAG--LYVGT-NSESTLKSIMKKKDGNRDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPPEEEEE-----EEEDEDTRGMAEGHHAVNMEGF
KSARVE-DEMQVPECEPEKVEIRERYELSEKMLSACNLLKNNINDPKALTSKDM------
-----------------RSCLNTLQHEWFRVSSQKSACPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAVSPDVLRHI
INMADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEVEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRSSFD-

-----------------KEG--------SEGKAGDILNGDQDKEQKD

PF12075 // ENSGT00530000063448_3_Domain_0 (48, 86)

PYFVETPYGYQLD
LDFLKYVDDIQKGNTIKRLNIQKRR

ENSGT00530000063448_3_Linker_0_1 (86, 1247)

KPSVPCPEP-RTT---SGQQGVWTSTES-LSSSNS
DDN-KQCPNFLIARSQVTS--TAISK-PPPPLETSLPFLTIAENRQLPPPSPQLPKHNLH
VTKTLMETRRRLEQERATMQMTP--GEFRRPRLASFGGMGSTSSLPSFVGSGNHN-PAMH
QLQNGYQGNGDYGSYAPAAPTTSSMGSSIRHSPLSSGISTPVTNVSPMHLQHIREQMAIA
LKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQNNVCGVRKRSYSAGNAS
QLEQLSRARR-S-GGELYIDYEEEE-METVEQSTQRIKEFRQLTADMQALEQKIQDSSCE
AS-SELRENG------ECRSVAVGAEENMNDIVVYHRGSRSCKDAAVGTLVEMRNCGVSV
TEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETTHDREMTKLKQELQAAGSRKK
VDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGTSVETNSVGISCQPECKNKVV
GPELPMNWWIVKERVAMHDRCAGRSVEMCDKSVSVEVSVCETGSNTEESVNDLTLLRTNL
-NLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEAAVMAVPRTADQDTSTDLEQ
VHQFTNTETATLIESCTNTCLSTWDKQTSTQTVETRTVAVGEGRVKDITSSTKTRSIGVG
TLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIACGPPQ---LTVGLTASRRS
VGVGGDPVGESP-ENP-QPQAPPGMMTGLDHYIERIQKLLAEQQTLLAENYSELAEAFGE
PHSQIGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGK--ITGNYLGYTC--K-C
GGL-QSGSP-LSSQTSQ----------SEQEVGTL-EGKP------ISSLDAFPTQEGTL
SPVNLTDDQIAAG--LYACT-NNESTLKSIMKKKDGNKDSNG--AKKNLQFVGINGGYET
TSSDDSSSDESSS-SESDDECDVIEYPLEEEE-----E-EEDEDTRGMAEGHHAVNIEGL
KSARVE-DEMQVQECEPEKVEIRERYELSEKMLSACNLLKNTINDPKALTSKDM------
-----------------RFCLNTLQHEWFRVSSQKSAIPAMVGDYI

PF12796 // ENSGT00530000063448_3_Domain_1 (1247, 1335)

AAFEAMSPDVLRYV
INLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDM
RVVEELFGCGDVNA

ENSGT00530000063448_3_Linker_1_4 (1335, 1344)

KASQAGQTA

PF12796 // ENSGT00530000063448_3_Domain_4 (1344, 1430)

LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM-C
ASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHVNFAKAQSPG
TPRLGRKTSPGPTHRGSFD-