Query Results 

------------------------------------MDGEA-----TVKPGEQKEVVRRG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVAN-RRAGWKMPLFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRA-----MGTLTPSSP----LCWQ-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

SRLVSG
EPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENN-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAAGE-----LTMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRETPGA-TRLATPGTGSWAEG-
S----VKAP-A------PIPES-------PASKAPAPIPESPASKSRSMSNTTEGVWE-G
TRS----LV--TNRAK---AS---KDRREITTTKADRPREDT--EG--------------
--------VRIALDAAKKVLGTIRPPAL----VSE----TLAWEIFPQA-----------
---TPVS-------------KQQSLSSIGETTPAAGMWTLGTPAADV------------W
I-LGTPTADVWTSM-EAAS-GEG-SSAGDLD----------------------AAT----
-----GDRGPQVTLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSTFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTHFL-EVNPQPD-QLPHVER-------KMLQ-DDS--
-LPAGASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TVKPGEQKEVVRRG
REV-DYS------------------------------------------RLIAGT-LPQS
HVTS-RRAGWKMPLFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRA-----MGTLTPSSP----LCWR-EESSF--------AAPNSLKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 345)

SRLVSG
EPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NQYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENN-M--LFL---------SMNLTI
SAGPAS--TLP-TATPAAGE-----LTMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRQTPGA-TRPAAPGTGSWSEV-
S----VKAP-A------PIP-------------------ESPPSKSRSMSNTTEGVWE-G
TRS----SV--TNRAR---VS---KDRREMTTTKANRPREDI--EG--------------
--------VRIALDAAKKVLGTIGPPAL----VSD----TLAWEILPQA-----------
---TPVS-------------KQQSQGSIGETTPAAGMWTLGTPAADV------------W
I-LGTPAADVWTSM-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWG--PP--------------------
-------GKESSV--KRTFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLW
R-RRT---SQEAE---RVTLIQMTHFL-EVNPQPD-QLPHVER-------KMLQ-DDS--
-LPAGASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDIFLWILFFLPI--------SKAWKPLKEIKL

PF07686 // ENSGT00530000063436_0_Domain_1 (239, 360)

FG
ELGGSINIKCPLE-----IPQQRYYLCREK---GKWCSTVVSS---SPFVAKDYKDRVSL
TPF-----PEDKVFMVELRNLKEEDNGNYACGTGYRTDRG--KTQ---------RVILTV
NTE----------YYPFWD-PDYFEA--------------------------LPPP---W
LWTPIEAS-SLSTTQAT-STSAPRTQPK------QTQPPLGPSPTSSVLTH--------R
TT----------------------------------------LAATTPSPTSSSS-----
------VTTKTLHLDRLPRLFTVSNSHHIR-LQGESASYFG---------SSVKK-DG--
-----GFHNLILVTLGIFLMMFL----GMVLGRLLQKKR-A-LS-KRINRLAMRMSALE-
A---SQRTH-SQLHHSRQRRL-------------PRPVSNRLRS-----QHNIYSACPRQ
VQR----PTQNGEQT----SA--------------SSPSI-----T--------------
-----------------------EPSAPP--QVSKMAQLQAP---VPVMNEY------MS
TYQLCLAEAEESD--SHDYINVSCLTQLPNCSPDLGFCANQACR----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTRF-----------------FYACLLAIFPVV--------SMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 335)

PQDVSS
VEGSSVSIRCYYPA-TSVNRHSRKYWCRIGA--KGRCTTLISS---EGYISKDYKGRANL
TNF-----PENGTFVMDIGHLTRGDSGLYKCGLG

ENSGT00530000063436_0_Linker_1_2 (335, 388)

IS-SRG--LSF---------DVSLEV
SQG--------------PGQIGDVHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 502)

TADLGSTV--TI-------------------NC
PFKSENAQKPKSVYKKL-GQIRVLVIDSN--GYLN------NNFTNRAHLSIQ-GTNQLV
FSFVINRIQLRDAGIYICQAG

ENSGT00530000063436_0_Linker_2_3 (502, 558)

DE---------------------ESSADLQVLK--PEPE
LIYG-----------DL

PF07686 // ENSGT00530000063436_0_Domain_3 (558, 661)

RGSVTFDCALGQE-MANVAKF------------LCQLKNGKTC
NVVINTLGKKAQDFEGRILLTPKE--NSHFSVHITGLRKED-AG---HYLCGAHPDGEPK

ENSGT00530000063436_0_Linker_3_4 (661, 683)

EGWPVQAWQ-LFINEDTMIPPR

PF07686 // ENSGT00530000063436_0_Domain_4 (683, 798)

SSVVRGVVGGSVAVTCPYNPKE-----TNSLKYWCRWE
ENE-NGRCPQLVESSGLVNEQ---YEGR---LALYEEPGNGT--FTVILNQLTNRDAGFY
WCLTNEDSRWRSTVELK

ENSGT00530000063436_0_Linker_4_5 (798, 813)

IVEG--EPNLKL---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 911)

PENVTAWVGE--TLKLSCHFPCKFYS--
-YQKYWCKWSNTG--------CRALPSQDEGQSQAFVNCDKKSQIISLNLNPVRKEDEGW
YWCGVKDGLHYGETGAVYVAVEQK-AKGSGDA--R-------------LA----NA-APA
PAEDAIEPRAR------ETEN----------------------EVLLDPSLIAEDRA-VK
DGEGPASGSGVPAA-PGSSVGQG--GGSKAVVSTLVPLA--LV-MLVGAVTIGVLRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFGAHDNAGATLD--TQETSLGGKDRF--
-TTT--------TENTMEDKEPKRAKRGPDSPLVGLEDICSWGAMPAPGGPFRPHLAVSH
YSSKEEA-DKAFTTFLLQANSIIA-ATQNGP--REA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 334)

PIFGPEEVNS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--SGRCITLISS---EGYVSNNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGRYKCGL

ENSGT00530000063436_0_Linker_1_2 (334, 384)

GIN-IRG--LSF---------DVSLEV
SQD--------------PGLLND

PF07686 // ENSGT00530000063436_0_Domain_2 (384, 525)

TKVYTVDVGRTV--TI-------------------NC
PFKTENAPKTKSLYKQI-GLSPVLVIDST--GYVN------PNYMGRIHLDVQ-GTGQLV
FSVVINRLRLSDAGQYLCQAGYG-SNSN----------------

ENSGT00530000063436_0_Linker_2_3 (525, 559)

KKNADLQVLK--PKPQ
LVYE-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 659)

GSVTFHCALGLE-VANVAKF------------LCRESSEENC
DVVINTLGKRAPAFEGRILLNPQD-KDGSFSVVITGLRKED-AG---RYLCGAHSDGQ

ENSGT00530000063436_0_Linker_3_4 (659, 681)

LQ
EGSPIQAWQ-LFVNEESTIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 783)

HSPTVVKGVAGGSVAVLCPYNPKE-----SKSIKYWCLWE
GAQ-NGRCSLLVESQGQVKEQ---YEGR---LSLLEEPGNGT--FTVILNQLTSQDAGFY
WC

ENSGT00530000063436_0_Linker_4_5 (783, 813)

LNNGDTRWRTTVEIKIIE--GEPNLKV---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 913)

PGNVTAVLGQ--TLKVPCHFPCKFSS--
-YEKYWCKWNNTG--------CQALPSQDKGPSKASVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEERKAAGSRDV--S-------------LAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKA-VA
DTGNQAGGSRASVD-SGSSEEQG--GSSRALVSTLVPLG--LV-LAVGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATTEST--------TETREPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQSSTVAA-EAQD-----------SPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------

PF00047 // ENSGT00530000063436_0_Domain_1 (260, 332)

MHVRIYLCREMAA-SGTCGTVVST---TNFIKAEYKGRVTL
KQY-----PHKNLFLVEVTQLTESDSGVYACGAGMNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPAYASSSKFVTRV---------TTPA--QRTKVPPVHYSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVASDKPPTFLPS-----
----TTA-SKISALEGLLKPQMPSYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTILGLFLLALL----GLVVKRAVERRK-A-LS-RRARRLAVRMRALE-
S---SQRPR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------TG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWLHAP--SLKTSCVY------VS
LYHQPATMMEDSD--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTLF-----------------LLACLLAAFPVV--------SMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 336)

PQEVSN
VEGNSVSITCFYPP-TSVNRHTRKYWCRQGA--SGRCTTLISS---EGYVSSNYVDRANL
TNF-----PGNGTFVVDIAQLSQNDSGRYKCGLGL

ENSGT00530000063436_0_Linker_1_2 (336, 387)

N-NRG--LSF---------DVSLQV
SEG--------------PGLLKDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------DC
PFKAENTQKKKSLCKQI-GEHCIAVIDTN--EYVN------PQYSGRVSLTIE-GTGQSK
FSVVITQLKLSDAGLYVCEAGED-SNAD----------------KKNIDLQVLE--PEPE
LVYG-----------DLRGSVSFDCALGPE-VANVAKF------------LCRLSKGETC
DVVVNTLGVRDSSFEGRILLTPED-ENGHFSVLITGLRKED-TG---RYLCGAHSDGLPQ
DGSPIQAWQ-LFVNEETTIPHSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 798)

SVVKGVVGGSVAVLCPYNPKE-----SSSLKYWCRWD
GAQ-NGRCPLLVESQGLVQEE---YEGR---LALHEEPGNGT--YTVILNQLTAQDAGFY
WCLTSGDGRWRSTVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VIE--GKPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PEKVTAVLGE--SLKLPCHFPCKFYS--
-HEKYWCKWSNRG--------CPALPTQDEGPSQAFVNCDQNSQIISLTLNPVTKADEGW
YWCGVKQDQHYGETVAVYVAVEET-VQGSSAV--S-------------PVSA-----NTA
PGEEVVESRVR--------E---I-----------------EHKAAQDPRLFAEERV-VE
SAGDQADGSRASAD-TSSSEGQG--GSSKLLFSILAPLG--LV-MALGAVAVGVARARHR
--KNVDRVSI----ASYRTNISMSDFE-NSREFGANDNLGASPV--TQETSLEGKDEF--
-DTTTEST--------METKEPKKAKR---------------------------------
-SSKEEA-EMAYTAFLLQASNVAA-EAQDTP--EEV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGLFL-----YQ--LSLSLSLSLFLSLSLSFAV--------SGALRILPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LDG
ELGGSIIIKCPMP-----DINVRLYLCRQMTK-SGACVTVVSS----TFIRKEYWDRITL
KPC-----SDKNLFLVAIMKLTESDSGIYACGVGKYTDLG--KTQ---------KVILNV
HNA----------YEPFLEEEP-----ISGP--------PEWFHRYLHM--QM-PK---W
LQIVTQTSSSESIAAV---------TTPA--QRMESSPAHHSSPTTL--AIHY--PGVSR
TS----------------------------------------SVATAKPPTLLTT-----
------TTSKTPTQEGLFGHQVTSYNYHTR-Q---RSFYHS------DGSSSGSL-DQ--
-----GFHILVPTILGLLLLALL----WLVIKRAVQRRKGEPLS-WGLGRGAALPS----
----TQHIW-T-----GLGPQ----------------RASGRLP-----RNNVYSACPWR
ARG----PDPAERLK----II---YP------------VS-----V--------------
-----------------------MLLGYP--QVSEAPRLLAQ--PWKASYEY------VS
LCHKPAVEMVDTD--SDDYVNIANLTHLPGCSLGPIPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLFFLPV--------SGALRMLPEVK

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 358)

LEG
EPGGSITIECPL-----PEPHERLYLCRVVAT-SGVCSTVVSN---TNFVKEEYKSRVTL
QRS-----PDKHLFLVEVTELTESDSGVYACGAGRDTDRD--KTQ---------QVTLSV
SRE----------YNPFLEEML-----KPEP--------SRWFPSRLHL--PM-PFTALW
PHVP-TEATPEFISKV---------ATTV--QRTQTPPVHHSSPSSP--ITHH--PQVAS
IS----------------------------------------SAPAAKPPTLQPS-----
----TS------AQVALLRLRTASYNHHTR-LHRQRAFNRG--------LSERTE-DQ--
-----GFHILIPTILGLILLALL----GMMIKRSIRRRK-A-FS-RRVRRLAMRMRALE-
A---SQRRL-S------QRPR----------------ASQRPRP------QNIYSACPRR
ARG----EEAAG------------EQ-A----PPRPGPGA-----S--------------
-----------------------EASAGL--QVSGTLWLPGSWEVLKTSCEC------LS
FDCQPPAKVGGAD--SEDYINIPCLTHQPGSPSRPGSLCQGASSVY--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEVK

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

VEG
ELGGSVTIKCPL-----PEMHVRMYLCREMVG-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PHKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVGDKPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------FLFWYW--ELNPV--------SGALKILPEVN

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 361)

LDG
ALGGSVIVKCPLA----GETQVRMYLCRQMPE-TQICSTVVSN----NFVKSEYKHRITL
KPC-----SDKNHFLVEISELTESDSGVYACGLGRNTDRG--KTQ---------KVTLNV
HNE----------YEPFWDEEE-----PMPE-------AQKWFHKFVQQ--HV-PS---W
LQMAVHARASEFIPKV---------TTPI--QRTEAPLVHHSSTTTP--TTHQ--PRIST
AY----------------------------------------VAATAKPPTFAPS-----
----TTA-SETLVKEQVLSPQEASYKRRTW-LYRQR-LEPLP--------SAGRE-DQ--
-----GFHILIPSVLGFLLLALL----GLVLRRAVQRRR-A-SA-PPSSRPLTLAG----
--------P-G-------------------------------------------------
---------EA----------------------------P-----A--------------
-----------------------REAPAP--SVPETPWLHAP--SRKTSCEY------VT
ICHQPVGQREDPDSDEDDYINIPNLTSLPTY-PGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--

PF07686 // ENSGT00530000063436_0_Domain_1 (243, 339)

GGSITHQCFYPA-TPANKHGRKYWCKIAA--DGLCYTIISS----SFTASEYQGRVAL
GDV-----PQNGTFTVTMTGLRSSDSGTYRCGIGST-N

ENSGT00530000063436_0_Linker_1_2 (339, 385)

KG--LYA---------SLNLTV
LAA--------------SALPRRT

PF07686 // ENSGT00530000063436_0_Domain_2 (385, 505)

KLLSGTV-GGS-LSF-QCHH----------DPKGTY
--------ERKYLCRQA-GSGCPTVVST---QYVA------PAYQGRVALTDH--PQAEH
FQINISALELGDAGTYQC---GVGVNGRGLSYRV--------TL----TPPVPET---PE
LFYV-----------KLRSTWTVTCSFGED-TVEMKKY------------LCKKE-KEGC
RNIINSYQEL-----GSIQLTFEE-PPGSFRVTMTQMDWED-AG---VYYCGAGEYGKDK
T---SKELE-VFIYEDKTFPHLK

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 794)

TDITAKNGSSATFECPYEPLI-----DSATRFWCKRD
GRI----CNRIIDNSGFVAKK---YKGR---VAAFENPENKT--VAIILNQLQYEDEGFY
WCMSNELREQQSSAELRVVA--GTEPPQPELTPSFKTARVGS--WVNLTCCYPCTYSS--
-YEKFWCRWNGTG--------CAMLPAQ-PGLPQPGDTCGPSSRTLVLSLGPLAEEDEGW
YWCGLKRNGLFGETMAV-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------PYS----ALALL-DYSLP--------LAANV

PF07686 // ENSGT00530000063436_0_Domain_1 (232, 344)

LKGPRLVSG
EPGGDVTIKCRYNP-TSINRHQRKYWCRLGPP-MWSCHTVVST---NPYTNLRYRGHVAL
EDF-----PQCGFFVVRLSQLLPEDVGHYRCGIGNRND-M--FFF---------SMNLTV
STGTRQ--VLPLSATVAAEE-----LAVRSFGTASPV-VNRWIPA---------------
----------------------------T--QTIEGQGTGCDRA----------------
-----------------------------------------------------AL-----
----TLEPSGMTAPT---------------------------------------------
------------------------------------KRGQSSGT-TGAIGPAMGSWVEG-
S----FRAT-V------STPES-------------------QTVKTGGLSKTSEGIWVWA
TKT----SI--RNRAG---ES---EGSREISTTKADRRGEET--RR--------------
--------VRIGLDGNWKVIGTIRSSTL----VSE----KWTWETLQEA-----------
---MPVS-----------------RGPIKA-TPAPGMWTLGTT-----------------
------------ST-ETAS-AEG-SPDGDQA----------------------GAA----
-----GDGGPQATSSQALAAG------------PQR--PL--------------------
-------AKGSSM--ESSSPEES--SLAGIL----TPVS--TVLVSFVLVPLVLLQRKLQ
S-RRT---SQEEARAPGVVLTQMTHLL-ELSLRPD-QPPHMER-------KMVR-GDS--
-PT-HASL-----AVPARDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MIGVR--------------
-QPHSRGSW------MG--PGLQGTMNLWLWLLYFLPV--------SGTLKVLPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

RLEV
ELGGSVFIECPLP-----QTHVRMYLCRQMTN-PAICATVVSN----IFVKKEYKRRVTL
KPS-----LNKKLFLVEMTQLTKDDEGIYACGVGTNTDLG--KTQ---------KVTLNV
RNEFPE--YP----EPFWDDEP-----TSEP-------SPRWWLHRYPE--EL--P---W
LKMGEHASPSGFIDKV---------TTLS--PKTEAPPVHQPSTNTS--VSRH--PRVYG
AS----------------------------------------SETPTKPSALLPA-----
----TTA-FKTSARQA-SRLLEASYSHHTR-LHGERTPHYG--------SQYGRE-DRGL
HISIPEFHILIPTFLGFLLLVLL----GLVVKRAIQRRR-A-FS-RRVGRMARRMRGRG-
P---SRQIP-T------QRRD----------------APQRPRS-----QNNVYSACPRR
ARE----PDNVG------------SA-E----ALLLNAPA-----S--------------
-----------------------APPALP--LVIETSWPHTP--SLKMSCEY------VS
LGHQPAVNVEDQD--SNDYINIPGLPHLPSKPPGPRPSRQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MPQPP
WKPQAMRLS-----------------LFALLVTVFSGV--------STQSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

PQDVSS
IEGNSVSITCYYPD-TSVNRHTRKYWCRQGA--NGYCATLISS---NGYLSKEYSGRASL
INF-----PENSTFVINIAHLTQEDTGSYKCGLGTT-NRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 388)

FF---------DVSLEV
SQV--------------PEFPNDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 531)

TKDIGRTV--TI-------------------EC
RFKEGNAHSKKSLCKKR-GEACEVVIDST--EYVD------PSYKDRAILFMK-GTSRDI
FYVNISHLIPSDAGLYVCQAGEG-PSAD----------------KNNADLQVLE--PEPE
LLYK-----------DLRSSVTFECDLGRE-VANDAKY------------LCRKN-KETC
DVIINTLGKRDPAFEGRILLTPRD-DNGRFSVLITGLRKED-AG---HYQCGAHSSGLPQ
EGWPVQAWQ-LFVNEESTIPNSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 798)

SVVKGVTGGSVAIVCPYNPKE-----SSSLKYWCHWE
ADE-NGRCPVLVGTQALVQEG---YEGR---LALFDQPGSGA--YTVILNQLTTQDSGFY
WCLTDGDSRWRTTIELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VAEATKKPDLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

TPQNATAVIGE--TFTISCHYPCKFYS--
-QEKYWCKWSNDG--------CHILPSHDEGARQSSVSCDQSSQIVSMTLNPVKKEDEGW
YWCGVKEGQVYGETTAIYVAVEER-TRGSPHI--N-------------PTDANARA-KDA
PEEEAMESSVR--------E---D-----------------ENKANLDPRLFADERE-IQ
NAGDQAQENRASGN-AGSAGGQS--GSSKVLFSTLVPLG--LV-LAVGAVAVWVARVRHR
--KNVDRMSI----SSYRTDISMGDFR-NSRDWEANDTWAPLQT--HKKQSSKEKMVC--
-ILKPRFGENRTGSPIQEGREMVRAKNT-------------------------------Q
HTTHTHTHMHAHSLFPLLSLSIQK---------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MALF-----------------LLTCLLAVFSAATA--QSSLLGPS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 336)

SIFGPGEVNV
LEGDSVSITCYYPT-TSVNRHSRKFWCREEE--SGRCVTLA-S---TGYTSQEYSGRGKL
TDF-----PDKGEFVVTVDQLTQNDTGSYKCGVGV

ENSGT00530000063436_0_Linker_1_2 (336, 393)

N-GRG--LDF---------GVNVLV
SQK--------------PE--PDDVVYKQYES

PF07686 // ENSGT00530000063436_0_Domain_2 (393, 503)

YTV--TI-------------------TC
PFTYATRQLKKSFYKVE-DGELVLIIDSSSKEAKD------PRYKGRITLQIQ-STTAKE
FTVTIKHLQLNDAGQYVCQSGS

ENSGT00530000063436_0_Linker_2_3 (503, 539)

D-PTAE----------------EQNVDLRLLT----

PF07686 // ENSGT00530000063436_0_Domain_3 (539, 666)

PG
LLYG-----------NLGGSVTFECALDSE-DANAV---------------ASLRQVRGG
NVVIDSQGTIDPAFEGRILFTKAE--NGHFSVVIAGLRKED-TG---NYLCGVQSNGQSG
DG-PT

ENSGT00530000063436_0_Linker_3_4 (666, 678)

QLRQ-LFVNEEI

PF07686 // ENSGT00530000063436_0_Domain_4 (678, 787)

DVSRSPPVLKGFPGGSVTIRCPYNPKR-----SDSHLQLYLWE
GSQT--RHLLVDSGEGLVQKD---YTGR---LALFEEPGNGT--FSVVLNQLTAEDEGFY
WCVSDD

ENSGT00530000063436_0_Linker_4_5 (787, 816)

DESLTTSVKLQIVDGEPSPTI------DK

PF07686 // ENSGT00530000063436_0_Domain_5 (816, 915)

FTAVQGD--PVEIACHFPCKYFS--
-SEKYWCKWNDHG--------CEDLPTKLSS-SGDLVKCNN-NLVLTLTLDSVSKDDEGW
YWCGAKDGHEFKEVAAVRVQLTEPAKVAVEPA-KV-------------PVDP-AKA-APA
PAEEKAKAC--------------PV-PRRRQWYPLSR----KLRTKSKPRLLAEEVA-VQ
SAEDPASGSRASVD-ASSASGQS--GSAKVLISTLVPLG--LV-LAAGAMAVAIARARHR
--RNVDRVSI----GSYRTDISMSDLE-NSREFGAIDNPSACPD--ARETALGGKDEL--
-AMATEST--------VEIEEPKKAKR---------------------------------
-SSKEEA-DLAYSAFLLQSNTIAA-EHQDGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTPL-----------------LFTCLLAVFSAV--------TAHSSIFGPEEVTV
LE

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GSPVSIKCFYPN-SSVNRHSRKFWCQPDS--TGRCMTLIS----TDFISAAYKGKAKL
TDF-----PEENSFVVDISEVDLDDTGSYKCG

ENSGT00530000063436_0_Linker_1_2 (333, 377)

VGVN-DRG--LDF---------TVSLHV
NKD-------------

PF07686 // ENSGT00530000063436_0_Domain_2 (377, 533)

-PGS----TGYTADLGGEV--TI-------------------TC
TFTDETRANKKTLYKLI-GPDREAIIDTD--KQVA------LDYIGRITLNIE-STTDLK
FTVTIKKLRASDSGIYICQSGYK----------------------NEIELQVRV--PDPV
LLYG-----------NLKSSVIFDCALSTV---YSAVF------------LCHVKDETTC
EVVVNSLGE-NPDFKGRVWLKSRS--EGNFSVVVAGLQKED-SG---DYLCGSSLTGHPQ
RDCPVQYWR-LFVNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----X-XXXXXXXXX
XXXXXXXCQSLVDNDGKVAQG---FAGR---LRLIQEPGNGI--FTVIFAKLTEEDDGFY
WCAAGNGNPLYTPVK

PF07686 // ENSGT00530000063436_0_Domain_5 (796, 920)

VQVVEG--KPGLAS--------VKAED--TVTLRCQFPCKYNS--
-YEKYWCKWSSQD--------CEALTTQEEDASDDVVNCRLISKVLS-----VNAGDEGW
YWCGVKQDQNYGEVVAVRVPVEAT-VEETVKV------------------SSLAKA-EPL
PAEEKVQGP--------------------GPWEVDSK--VVNNQVVANPKLLAEEAV-VE
SAGDPASGSRASVE-SSSSQGQS--GTSKVLLSTLVPLG--LV-LAAGAMAVAVARARHR
--RNVDRVSI----GSYRTDISMSDLA-GSRDFGAIDNPAACPE--ARETSLEGKDEV--
-TITTEST--------VEIQEPKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSAMAT-EHQDDP--TEP---------

------------------------------------MDGEA-----TVKPREQKAVVRRG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVTN-RRPGWKMPLFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRA-----MGTLTPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 345)

SRLVSG
EPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENN-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAAGE-----LTMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQGTARDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRQTPGA-TRPEAPGTGSWVEG-
S----VKVP-A------PIP-------------------ESPASKSRSMSNTTEGVWE-G
TIS----LV--TNRVR---AS---KDRREMTTTKADRPREDT--EG--------------
--------VRIALDAAKKVPGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGSIGETTPAAGMWTLGTPAADV------------W
I-LGTPAADVWTSM-EAAS-GEG-SAAGDLD----------------------AAT----
-----EDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSTFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTHFL-EVNPQAD-QLPHVER-------KMLQ-DDS--
-LPAGASL-----TVPERNAGP--------------------------------------
---------------------------------------------

------------------------------------MDGEA-----PCKPRECKLALPSS
------------------------------------------------------------
-SLGVLWPSVALTAQPSLC--PGSSLAPPHSGPHLGRL----------------RAGPP-
--PPGTHLCA-----EEALS---------------SSS--------ALCSTLN

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

SPRLVSG
ELGGAVTIQCHYAP-LSINRHQRKYWCRVGPP-MWTCHTIVST---NHYTHRDYRGRAAL
ADF-----PQSSLFVVRLSQLSMEDGGHYRCGIGDSNN-R--LFS---------SVNLTV
SAGSSS--TIP-TAPAAADA-----FLTASFRTASPA-ADRWTSGS--------------
----------------------------T--QTLEGQRTKWDRV----------------
-----------------------------------------------------VP-----
----TTETRRTTASA---------------------------------------------
------------------------------------KRRQTPGT-VRAVALGTDRGAEG-
S----TEAT-V------PVPQS-------------------PVSKLRGVSTTTEDVWGWG
TGS----MV--TEGTG---VS---EGGKEVTTTEASKPGEQT--ET--------------
--------TETAVDAARKSTETTSPPA-------------QAWETLPEA-----------
---TMVS-------------KQQALVSAEGATPAAGPWTLDTT-----------------
------------RR-ETAS-VEG-STEAELS----------------------SAA----
-----GDQGPQATTSQGPAAR------------PQR--PP--------------------
-------GKESSE--KSAFPEDE--SGSWAL----APVS--AMLAPFLFVALLLWQRRLW
R-RRR---RR-RKGTPRIALIQMTRFL-ELNHQPD-QLPNMER-------EMLQ---RDP
PHPPQASL-----TVLEEDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MRLPLILPEI

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
EVGGSVTIKCPL-----PEMHVRMYLCREMVG-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--PRTKVPPVHHSSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVGDEPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWFHAS--SLKSSC--EY----VS
VYHQPAAKMEDSN--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MD---------------TEATVKE
AEA-DYC------------------------------------------RLIAGT-SPQS
HFSCIRTAGWKMPFFLILCLLQGSSFALPQKRPHLRWL----------------WEGSL-
--PSRTHLQT-----MGTLMPSSP----LCWR-EGSSF--------AAANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
DPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYIHHHYRDRVAL
TDF-----PQRGLFVVRLSQLSPEDIGCYLCGIGDENN-V--LFF---------SMNLTV
SAGPSS--TLP-TATPATGE-----LPMRSYGTAPPA-ANRWTPGT--------------
----------------------------T--QT-LGQRTAWDTV----------------
-----------------------------------------------------AS-----
----APGSSMTRASA---------------------------------------------
------------------------------------EGRQTSGA-ARPAAPGTGSRAEG-
S----TKAP-A------PIPES-------PASES-----------RSRMSNTTEGVQG-G
TRS----SV--TNKAR---AS---KDGREMTTTKVDRPREDT--ER--------------
--------VSIALEAAKKSLGTVSPPAP----VSE----TLAWEILPQCCLE--------
---TSVS-------------KQQSLGPIGETSPAAGVWTLGTT-----------------
------------SI-EAAS-GEG-SAAGDPD----------------------ATT----
-----GDRGSQATPSQALAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SDSWTL----APVS--TLLVLFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTRVL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-CPAGTSL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
----------------------------------------------MDQDAPAKPR---E
QKVTSLRTKWKI-LLLILCLLHGSSMTPPHRRPHSRWL----------------QSGSQ-
--QFRAHLYS-----VEAHTVATT----LCCW-K-NSL--------SGANALR

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPKLVSG
ETGGTVTIRCHYAP-TSVNRHQRKYWCRLGPP-LWICYTVVST---NQYTHHDYRGRVAL
TDV-----PQSGLFMVRLLQLSLGDTGLYRCGIGDRND-M--LFF---------SVNLTV
SAGPSN--TTYAA-APASSE-----PITASPGTASSA-ANRWTSGV--------------
----------------------------T--QVLEGRGSEWDRS----------------
-----------------------------------------------------AP-----
----TPDTSKTTSSA---------------------------------------------
------------------------------------NGRQTLTT-ARTMVPRTSSREEG-
S----VKVA-V------STPEG-------------------PAPKSGSLFSTTQGVWVWS
TRN----SV--TTGAT---TS---EGRKQGTTPETDGPREET--N---------------
--------VSTSPNAPRKTTGTTRPSVL----ISE----HGTWETLQDE-----------
---TKVS-------------KQQMLYSPEGSSPAPSAQTLNAT-----------------
------------CM-EAAP-GEGR-TDGSLG----------------------NTT----
-----EES-SPLTPSQLSAAG------------PMW--VS--------------------
-------GKGSSM--KSTFTERE--SDSRIL----TPVS--IVLALLLIAALVLLKRRLG
GERT----SQKTERVPRITLIQMTHF------LPD-KLPGEGK-------NLQQ-SDL--
--PTQASL-----TVLEKDPGL--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRLF-----------------LLTCLMAVFPVV--------FMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

PAEVSS
VQGSLVSIKCYYPA-TSVNRHTRKYWCRQGS--RGVCTTLISS---EGYISKDYLGRANL
TNF-----PEEGAFVVNISQLSRDDSGRYKCGLGIS-SRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 388)

SF---------DVRLEV
SQG--------------PDPQDDIEVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 533)

TVDLGRTV--TI-------------------NC
PFKRENSQKMKYLFKET-GEL---V-INT--NYVN------PNFKGRASIVIQ-GTNQLM
FNVIIKQLRLSDAGIYICQAGDG-SSSN----------------KKYVDLQVLE--PEPE
LLYG-----------ELRGSVNFDCALGPE-ETNVAQF------------LCRVNSQGSC
DVVINTLGKRDPAFEGRILLTQR--ENGHFSVLLTGLKKGD-AG---RYLCGAHPGGQQK
EGWPIQAWQ-LFINEETVIPS

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 798)

NPTVVKGVTGGSVSLLCPYDQKE-----SNSIKYLCRWE
GTQ-NGRCPLLVSSDGEVQEE---HEGR---LALFKEPGNGT--YTVILNQLTTQDAGFY
WCLTNGNTRWRTSTELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

IVEA-GKPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 913)

-PENVTAVLGK--SLELQCHFPCKYYT--
-FEKYWCKWSNGE--------CRELPSQDKSPSQALVTCDQNNRFISMTLNSVVKEDEGW
YWCGVRKDHNYGETAAVYVAVEQV-AVGSREV--S-------------PANT-----NPG
AEEKVAEPTVR--------V---I-----------------ENKAVVNPRLFAEERAVVE
DTGDQESGIRASSD-TSSSEGQS--RSSKVLLSTLVPLG--LV-LTAGAVAVWVARARHR
--KNVDRVSI----RSYRTDISMSDFD-NSREFGAVDNMGAAPV--TQETILEEKAEA--
-MATPEGN--------TEPEEPKRAKR---------------------------------
-SSKEEA-DMAYSAFLLQSGKIAA-QGQEEP--SEV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------M--------QAANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 359)

GPRLVSG
ELGGAVTIRCHYTP-LSINRHQRKYWCRLGPP-TGTCHTVVST---NHYTHPGYRGRAAL
ADF-----PQSSVFVVRLSQLSTRDEGHYRCGIGNSNN-A--LFF---------SVSLTV
SAGSSR--AIP-TAPPAAGE-----FLTEPFGAASLA-ANRWTSGA--------------
----------------------------T--RTLDGQGTKWDRA----------------
-----------------------------------------------------VP-----
----TTETRKTTASA---------------------------------------------
------------------------------------QRRQTPGT-VRAVARGADSGAES-
S----IQAT-V------PVPQS-------------------PVSKLGGLSSTTEDVWGWG
TWR----LV--TEGAG---LR---EGGKAT---GTGKPGEQT--ER--------------
--------TEIAGDAARKTTGTISPSA-------------QAWETLPEA-----------
---AVVP-------------KQQALVSTDGASGAASPWTLDTT-----------------
------------RR-EPAS-VEG-SPGGDPS----------------------SAA----
-----GDQGFQATPSQGPAAG------------PRR--RP--------------------
-------E-ESSR--KSAFPEGE--SGSWTL----TPVF--VMLAPFLLVALVLWQRRLW
R-RRS---SREAERTPRVTLIQMTRVL-ELNLQPD-QLPNVKK-------LQGD---PLP
PPPPQASL-----PVLERDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLRLLYFLPV--------SGALRVLPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 361)

LDV
EWGGSIIIKCPLP-----QLHVRMYLCRQMVN-PGLCTTVVSN----NFVRKDYERRVTL
KPC-----LDKKLFLVEMTRLTENDNGVYACGVGTNTDRG--KTQ---------KITLNV
HNE-----YP----EPFWEDEW-----TSEP--------PRWLHRFLQH--QM--P---W
LHRGEHASSSGVIAKV---------TTPT--PKTEAPPVHQPSSITS--VTQH--PRVYR
AF----------------------------------------SISATKSPALLPATKSPA
LLLATTA-SKTSTQQA-IRPLEASYSHHTR-LHGQRTLHHG--------PHYGRE-DRGL
HIPIPEFHILIPTFLGFLLLVLL----GLVVKRAIQRRR-A-SS-RRTGRLAMRRRGQG-
A---SRPFP-T------QRRD----------------APQRPRS-----QNNVYSACPRR
ARG----PDSVG------------PA-E----APLLNAPA-----S--------------
-----------------------VCP-SP--QVLEAPWPHAP--SLKMNCEY------VS
LGYQPAVNPEDPD--SDDYINIPGPSHLPSCAPGPRSSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRLS-----------------LFTLLVTVFSGV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 335)

PQDVSR
IEGESVSITCYYPD-SSVNRHTRKYWCRQGA--RGMCTTLISS---NGYLSGEYSGRANL
INF-----PENSTFVITIEQLTQNDTGSYKCGLG

ENSGT00530000063436_0_Linker_1_2 (335, 388)

IS-NRG--LSF---------DVSLEV
SQV--------------PEFPSDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TKDIGRNV--TI-------------------EC
PFKRENAPSKKSLCKKT-NETCELVIDST--EKVN------PSYKDRAELFMK-GTNPNV
FYVNIRHLMHSDGGLYVCQAGEG-SSAD----------------KKNIDLQVLK--PEPE
LLYK-----------DLRSSVTFECDLGRE-VANEAKY------------LCRMN-KESC
EVIINTLGTRDPAFEGRILITPKD-DNGRFSVLITGLRKED-AG---NYQCGAHSSGLPQ
EGWPIQTWQ-LFVNEESSIPNSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 798)

SVVRGVTGGSVAIVCPYNPKE-----SSSLKYWCHWE
GDG-NGHCPVLVGTQALVQEE---YEGR---LALFDQPGNGT--YTVILNQLTTEDAGFY
WCLTNGDSRWRTTIELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VAEASREPNLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

TPQNATAVLGE--TFTISCHYPCKFYS--
-QEKYWCKWSNTG--------CHILPSHDKGARQSSVSCDKSSQLVSMTLNPVSKEDEGW
YWCGVKQGQTYGETTAIYVAVEER-TRGSPHV--N-------------PTDANARA-KVA
PEEEVVDSSIS--------E---K-----------------ENKVIPNPRLFADEKE-IQ
NVGDQAQENRASGD-AGSADGQSRSSSSKVLFSTLVPLG--LV-LTVGAIAVWVARVRHR
--KNVDRMSI----SSYRTDISMADFK-NSRDLEGNDNMGASPD--TQQTVIEGKDET--
-VTSTECP--------AEPEESKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSTIAA-QVHDGP--QEA---------

------------------------------------------------------------
----------------------------------------------MDQDVPAKPS---E
QKVPSLRTRWEI-LLLILCLLHGSSMTPPRRRSHSRWL----------------QAGSP-
--QFRTHLYT-----VEAHTAPIP----LCCW-K-NSI--------SGTNALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 359)

PQLVTG
DTGGAVTIHCHYAP-SSVNRHQRKYWCRLGPP-LWICHTVVST---NQYIHPDYHGRVAL
TDV-----PQRGLFVVRLLRLSLGDMGLYRCGIGDRND-M--LFL---------SMNLTV
SAGPSN--TTYAA-APASSE-----HITASPGTVSSA-GNRWTSGV--------------
----------------------------T--QILEGQGSEWDRT----------------
-----------------------------------------------------AP-----
----TTSTSKTTSSA---------------------------------------------
------------------------------------NGRQTLRT-ARTMVPGTGGREED-
S----FKAA-V------PTPEG-------------------PFPKSRSMFSTTQGVWMWS
TRN----SG--TTSAT---TS---EGRRQGTTPETDGPRDET--D---------------
--------VSVSPEAPRKTTGTTWP-------ISE----HVAWGTLQDK-----------
---TEVS-------------KQQRLHSLEELSPAPSTQTLNAT-----------------
------------CM-EVAS-EEGRSIDGSLE----------------------NTT----
-----EES-SPPTPSQLSVAG------------PVW--VS--------------------
-------GKGPSM--KSARIEGE--SNSRIL----TPVS--TVLALLLIAALVLLKRSLG
RQRT----SQKTERVPRITLIQMTHF------LPD-KLPDEGQ-------NFQQ-SDL--
-FPPQASL-----TVLENDPRP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLISS---EGYVSSNYAGRANL
TNF-----PENGTFVVNVAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTVDVGRTV--TI-------------------KC
PFKTENDPKVKALYKKI-GETSVLVIDSR--NYVN------PNYNGRIGLHIP-GTGQLI
FTVVIDRLRLSDHGLYLCQAGDG-SSRD----------------EKNVDLQVLK--PEPE
LVYA-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVSSRETC
DVVINTLGKRDSAFEGRILLNPQD-QDGSFSVVITGLRKED-EG---RYLCGAHSDGRLQ
EGWPIQAWQ-LFVNEESTIPHSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 791)

TVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCLWE
GTQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTHW

ENSGT00530000063436_0_Linker_4_5 (791, 812)

RTTVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------Q---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSRALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGACSI--TQETSLGGKDEF--
-VASPEST--------TENQEPKKAKR---------------------------------
-VRRKKEAPLCAKEMQHEGLQLDF-RKNYLN--MGADPRIGRMV-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWCWLLSLLPV--------SG

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 362)

ALKIIPEVKMEG
KLGGSITFKCPL-----PPVYSRIYLCREMAA-SGRCNTMVSSGKSGDFLKKEYSGRVTL
KAD-----PCKKLFLVQMTEMRQHDSGVYACGMGWVTDRD--KTQ---------KITLSI
-RE----------HDPFWDGEPATEELPPQT--------PEWL--------HL-PA---W
LLMPEDASPSELLVEV---------TTPA--ARTQASPAPPKLLSTPIIHLHR--PPITR
TS----------------------------------------SVTAGTFSRLPPS-----
----TTA-SKSSALEERPRPQPLSY-HHTR-LPRPRTFNYG--------S-SGSE-NH--
-----GFHILIPTILGLLLLALL----GMVVKRAVRRRK-V-LS-KRVRRLAIRMRALE-
A---SQRPR-R------P--Q----------------VSARQR------SQNIYSVCPMR
ARG----KAAA-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------I--------AA

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

KSPIFGPQEVTR
MEGSSASIQCYYPN-TSVNRHSRKYWCRQEP--KGACITLISS---GAFVSKQYMGRANL
TNF-----PEENRFVVDIRDLTQSDSGRYKCGVGVN-NRG--LSF---------DVTLEV

ENSGT00530000063436_0_Linker_1_2 (361, 379)

SKG--------------L

PF07686 // ENSGT00530000063436_0_Domain_2 (379, 544)

DFPLYTPLYTENVGGSV--TF-------------------QC
PFKVENAPWTKALYKKV-GDHSVLIIDSE----HN------PLYKGRVNLHVP-DTSQLL
FTVTLSQLRPDDSALYTCKAGQR----------------------KNAYLQVLK--PEPE
LVYG-----------DLRGSISLDCDLGSG-MEQVPKF------------LCRINDKDGC
DMVINTLGKKAPDFKGRILLTPMD-KNGVFSVLITGLKKED-AG---QYLCGANPDGVLE
PGWPLQAWR-LFVNE

PF07686 // ENSGT00530000063436_0_Domain_4 (676, 799)

ETNIPQTLSVVKGVAGGSVAVRCPYNPKE-----SNTLKYWCRWE
DNK-NGICPLLVESTGLVA-K---YKGR---LVLFEEPGNGT--YTVILNQLTPKDAGFY
WCLTNGNIRWRSTVELKI

ENSGT00530000063436_0_Linker_4_5 (799, 804)

ID--G

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 922)

KPKLQV---PEALSVLEGD--DLMFSCNFSCQYYS--
-YTKYWCKWSDTG--------CRTLPSQEEGSSQEVVTCDLNNQRISLTLKSVQKADEGW
YWCGVKQGNRYGETAAVYVTVLERKERFHDI---------------------ISKA-NAA
PGGEVVQPNVP------EF----------------------GNKAVLDPKLVVNEDF-V-
---EPAGESKAS---QGSAGRQG--GSSTVLVSTLVPLA--LV-LAVGAAVVGVLRARHR
--RNVXXXQI----RSYRTDISMSKLE-S--RFGPNDNKGVSSI--TQETSLGTKGYS--
-TATTGGA--------VETKDPKKAKR---------------------------------
---------------------------------------------

--------------------------------------------------C---------
-----------------------------------------------------------F
LQVANQRAGWKMLLLLILCLLRGSSLSPPHRGPHLRRL----------------LDGSL-
--PSGTHLWA-----VE--TPSSP----LCWR-E-SSL--------AVANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
KPGGAVTIRCHYAP-SPVNRHQRKYWCRLGPP-RWICRTIVSS---NRYTHHRYHGRVAL
ADF-----PQRGFFVVRLSQLSLDDVGCYHCGIGDRST-T--LFF---------SMNLTV
SAGPSG--TFP-TATPASGE-----LALRSFGTASPTANNRWTTGP--------------
----------------------------T--QTTEGQGTEWDRV----------------
-----------------------------------------------------AP-----
----TPGASTATASA---------------------------------------------
------------------------------------KGRQTPGT-TGTAAPGTGVWVEA-
S----VEAT-A------PVPES-------------------PASLTSSMSNTTEGVWMWG
TRS----SM--TNRAI---VS---KDRREMTTTQADRPTVET--ER--------------
--------ARISVDAARKVIGTSRPSAL----ASE----KLPRETPREA-----------
---TPVS-------------KQRFLGSIEGTSPAAGVWTLGTT-----------------
------------SI-ETAS-AEA-SAEGDLD----------------------TAA----
-----GDSGPQATPSQAPAAG------------PLR--PP--------------------
-------GKESSV--KSALPEK---SSSRIA----TPVS--TMLAPFVLAALVLLQRKLR
S-RRT---SQEAESTPGVTLIQMTRFL-QPSPQPD-QLPHVER-------KMLQ-DDS--
-PPAQASP-----TVPERDPGPQEVER---------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MSRL-----------------FLACLLAVFPVV--------SMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

PEEVTS
VEGRSVSITCYYPA-TSVNRHTRKYWCRQGA--KGRCTTLISS---EGYVSDDYVGRANL
TNF-----PESGTFVVDISHLTRNDSGRYKCGLGIS-

ENSGT00530000063436_0_Linker_1_2 (338, 389)

SRG--LNF---------DVSLEV
SQD--------------PAQASDAHIYP

PF07686 // ENSGT00530000063436_0_Domain_2 (389, 532)

VDVGRTV--TI-------------------NC
PFTSANSQMRKSLCKKT-GQGCFLIIDST--GYKN------ENYEDRIRLNIA-GTNTLV
FSVVINRVLLKDAGMYVCQAGDD-AKAD----------------KSNVYLQVLE--PEPE
LVYR-----------DLRSSVTFDCSLGPE-VADTAKF------------LCQQKNGEAC
NVVINTLGKKAQDFQGRILFLPKD--NGVFSVHIASLRKED-AG---RYVCGAQPEGQPE
EGWPVQAWE-LFVNEETAIPA

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 798)

SPSVVKGVKGGSVTVSCPYNPKD-----ANSAKYWCRWE
KDQ-NGRCPRLVQSKGLVKEQ---YKGR---LALLAEPGNGT--YTVILNQLMDQDAGFY
WCVTDGDTSWTSTVQLK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVEG--EPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PKNVTAWLGE--AFKLSCHFPCKFYS--
-FEKYWCKWSNEG--------CSPLPTQNDGPSQAFVSCDQNSQIVSLNLDTVTKEDEGW
YWCGVKEGPRYGETAAVYVAVESR-AKGSQDA--K-------------QV----NA-APA
--GGAIESRAG------E----------------------IQNKALLDPRLFVEEIA-VK
D---AAGGPGAPAD-PGRPAGHS--GSSKVLVSTLVPLA--LV-LAAGVVAIGVLRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFEGRDNMGASPE--AQETSLGGKDEF--
-ATA--------TEDTVESKEPKKAKR---------------------------------
-SSKEEA-DEAFTTFLLQAKNLASTATQDGP--TEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MGET-----------P-TKPEE--------QK

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ANALKGPRLVSG
EPGGAVTITCHYAP-TSVNRHQRKYWCRLGPP-NWICRTIVST---NHYTHLQYHGRATL
EDF-----PWSSMFVVRLSQLSPMDEGCYRCGIGSRND-M--LFF---------SVNLTV
STGLSS--TVP-IGTRAASE-----LTRGSLATASPE-ANRWTSGT--------------
----------------------------I--QTVDGQRVGWDRV----------------
-----------------------------------------------------DP-----
----TPGTSETTASS---------------------------------------------
------------------------------------TERQPPDI-TMAVTPGTGSRAGV-
S----IS-------------AT-------------------DPSQTTVLSNTTDDIWVPG
TRS----SE--ANRAM---VS---AEGRK-TTPNADGPMEER--TS--------------
--------VRVALDATWKAVGTIRPSTL----TSK----KWVWETFQEVT-S--------
-----RS-------------KPPALSNLEDTTPAAGAWTLGTI-----------------
------------GT-EMAA-VEG-SAKGGLV----------------------STA----
-----EESGLHATPSQATGVE------------PLR--PR--------------------
-------GTELST--E--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-----------------------ERACPGSPCCSPQLLTAP-----PQTS-ST-------
---------------------------------------------------------TVF
LQVANQRAGWKTPILLMLCLLQGSALTPLHRRPHLRCQ----------------WNGPL-
--PSGPHLLA-----QETLTPFSP----LCMK-EA-AT--------SAANALKGPRLVSG
ET

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GGAVTIQCHYTP-LSINKHVRKYWCRLSPV-TWICHTIVST---TNYTHLGYRGRVAL
ADF-----PRRGLFVVRLSQLSPDDGGRYRCGIGNRNN-M--FFF---------SMNLTV
AADTSS--NIP-MPTPAAGE-----LVMGSFGTVSQA-ANRQTSRT--------------
----------------------------T--QTIERQGTGWDRV----------------
-----------------------------------------------------AL-----
----TPGTNETTVSA---------------------------------------------
------------------------------------EGGQTPGT-TEAVAQVTSSQVEG-
S----VWAT-V------PIPES-------------------PASTTGGESNTTAGVWVWD
TRG----SA--ANRVR---PS---EEGRET-TTEADGLPEDT--ER--------------
--------VRTAPDVTGKFRGTSRPSTL----VSE----KWVLEILQEA-----------
---TTVS-------------KPQVLSSTEGTTPAASVWTLRQT-----------------
------------SI-ETAS-EEG-ATKGDLD----------------------MPA----
-----GDSDPQATPGQAPAAG------------SMR--PL--------------------
-------GKGSSM--MSAFPGEK--NISWIL----IPVS--TVLCPLTLAALGLLQKKLR
T-KKM---SEETERTAEVTLIQMTYFL-EPSHPPD-QLAHVGR-------SMLQ-DDR--
-PP-QASL-----TVPETCPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 335)

PIFGPQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLG

ENSGT00530000063436_0_Linker_1_2 (335, 383)

IN-SRG--LSF---------DVSLEV
SQG--------------PELSN

PF07686 // ENSGT00530000063436_0_Domain_2 (383, 526)

DTEVYTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQSSVLVIDSR--SYVN------PNYQGRIRLRIP-GTGQLI
FTVVIDRLRLSDHGLYLCQAGDG-SNRD----------------E

ENSGT00530000063436_0_Linker_2_3 (526, 559)

KNADLQVLK--PEPE
LVYE-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 655)

GSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGQRDSAFEGRILLNPQD-KDGSFSVVITGLRKED-EG---RYLCGAH

ENSGT00530000063436_0_Linker_3_4 (655, 682)

SDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 784)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LALLQEPGNGT--FTVILNQLTTQDAGFY
WCL

ENSGT00530000063436_0_Linker_4_5 (784, 813)

TNGDTRWRTTVEIKIIE--GEPNLKV---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 913)

PGNVTAVLGE--TLNIPCHLPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------

PF07686 // ENSGT00530000063436_0_Domain_2 (378, 533)

PGQINDVRVYTADLGRTV--TI-------------------SC
PFKAANLQKKKSVCKMM-SQSCVLIADTN--NYMN------PSYKGRAHISIQ-GTSQLV
FSFVINQVQLSDAGMYVCQAGDD-SSAD----------------KSNADLQVLK--PDPE
LIYG-----------DLRGSVTIDCDLGPE-VKSVPKF------------LCRLKNEEAC
DVVINTLKTKAPDFEGRILLTTGN--NGRFTVHITGLKKED-AG---LYLCGADSDGVPQ
KGSSTQAWQ-LFVNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXX
XXX-X-XXXXXXXXXXXXXXX---XXXX---XXXXXXXXXXX--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--XXXXXX--XXXXXXXXXXX--XXXXXXXXXXXXXS--
-SEKYWCKWSNTG--------CRTLPSQDQGASQAFVNC

PF00047 // ENSGT00530000063436_0_Domain_6 (880, 905)

SQQSQITSLNLNPVTKEDEGW
YWCGVKDGLQYGETAAVYVAVETR-VKGTQDA-R--------------------QA-SAA
HEEDAIEPRAR------EDI---------------------ENKVLLDPRLSAEERA-VK
KVEDPAGGSGVPAD-SSXXXXXXXXX--XXXXXXXXXXX--XX-XXXXXXXXXXXXXXXX
--XXXXRISI----RSYRTDISMSDFE-NSRDFGAHDNTAASPD--TQETSLGGKDES--
-APTIEDT--------TETKEPKKAKR---------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--SVLWTLRWPPDGSFPPCAP-GSALAPPGERPHLR-R----------------WAGSL-
--PRETR-----------TPSSHL----SWWE-E-RSI--------SA

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ANALKGPRLVSG
ELGGSVTIQCRYAP-LLINSHQRKYWCRLSPR-PWLCHTVVST---NHYTQRHYHGRVSL
TDF-----PHKGFFVVRLSQLSLEDVGCYRCGIGNSND-M--LFF---------SMNLTV
SAGLSR--TIP-TATPAAGE-----PNMGSSETASP-AANRWTRGT--------------
----------------------------I--QTIERQGTGWDSV----------------
-----------------------------------------------------TL-----
----TLDTSKTTALA---------------------------------------------
------------------------------------KGRQTPEA-TATIAPGTGGQVGG-
P----IWAT-V------PTPLS-------------------PASTIKSVSSTTKAAKVWG
TRS----SD--ANRTR---AS---RRERAT-XIGPSLVL---------------------
----------------------------------E----KMNVNNLHGE-----------
---TLVS-------------KQQALDSIEGTTPAAVVWTLGPT-----------------
------------SI-EMAS-AEG-SGERDLD----------------------TPA----
-----GDGGPQATPSQALAAG------------PLR--PP--------------------
-------GKDSSM--KRATGPDL--HTPKEIEFSTQGPH--SVLCV--------------
---CA---AQEIKKSLKVTLIQMTQSP-ELSVQPD-LLAQVGR-------KLLQ-DD---
-PPHPCSL-----TAPERDPGPQ-------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLCFLPV--------SGALKILPEVKLEG
TL

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 332)

GGSVTIECPL-----PVTRVRLYLCRQMAG-SGACATVVSN---SNFVKKEYKHRVTL
TPC-----PDRNLFLVEVTELTKSDSGVYACGAGTNTDLG--KTQ---------QITLNV
NSE----------YELLWEEES-----MPEL--------PQWF---------L-PP---W
FQTPAH--AFEFTTKV---------TTPA--QRTETPLAHHSSPTTL--ITYR--PRVSR
AS----------------------------------------SVAAAKPTTPRPS-----
----TAA-SKTSA----LRRQTASYTHHNR-LHRQRGFHHG--------LGSGTE-EQ--
-----GFHILIPTILGLILLALL----GLVVKRVIQRRKVE-Q--GKNRAGWLHLQKLS-
F---TRRPR----------------------------YISCWEA-----QKTLYSLKWRS
VSS----PVKAG------------SQ-E---AGPEP-PGH-----P--------------
-----------------------GT-PAP--SVSEAPWPQAS--SLKSSCEY------VS
VCRQPAAMMEDTG--LEDYVNIAC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------CRIYTA--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VVGNPVSITCYYPA-TSVNRHSRKYWCRKGA--NSLCTTLISS---NGYVSKEYAGRANI
INF-----PENNTFVVNIANLTQDDSGSYKCGLGTS-N

ENSGT00530000063436_0_Linker_1_2 (339, 388)

RP--LFF---------DVSLEV
SQA--------------PEFPEDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 533)

TEDMGRNV--TF-------------------EC
PFQKENSHSKKSLCKKI-GQTCELVIDST--GKVN------PNYKGRVKLFMK-GTSGEI
FGVSINHLRLNDAGLYVCQAGEG-SSAN----------------KKNVHLQV

ENSGT00530000063436_0_Linker_2_3 (533, 555)

LK--PEPE
LVYA----------

PF07686 // ENSGT00530000063436_0_Domain_3 (555, 657)

-DLRSSVTLDCALGRE-VANEAKY------------LCRMN-KETC
DVVINTLGKRDPAFDGRILLTPKD-NNGHFSVLITGVRKED-AG---HYLCGAHSS

ENSGT00530000063436_0_Linker_3_4 (657, 684)

GLPQ
EGWPIQAWQ-LFVNEESTIPPSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 798)

SVVKGVTGGSVAMVCPYNPKE-----SNSLKYWCRWE
GDG-NGHCPILVESQGVVQED---YEGR---LALYDQPGNGS--YTVILNQLTTQDAGSY
WCLTNGDSRWRTTIELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VAEGERKPDLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

TPQNATAVLGE--TFTLSCHYPCKLYS--
-QEKYWCKWSNKG--------CHVLPSRDEGARQPSVSCDPSNQLISMTLNPVKKEDEGW
YWCGVKQGQTYGETTAIYVAVEEG-TGGSRHV--N-------------PPDANAHA-DVA
PEKA-VESSVS--------E---N-----------------ENRPVLNPKLLAEEKG-IE
SVGDQAQENRASVN-AGSADAPT--GSSKVLFATLVPLG--LV-LAVGAVAVWVARARHR
--KNVDRMSI----SSYRTDISMSDFK-NSRDFGGNDNMGASPD--NQETVLERKDEI--
-MTTTEIA--------TEPEESKKAKR---------------------------------
-SSKEEA-DLAYSAFLIQSSNIAA-QVHDVP--KEV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTLL------AF--ILLLSFLPAESAKSRYPPK--------TSLNPVFGPQQVYG
LI

PF07686 // ENSGT00530000063436_0_Domain_1 (243, 340)

DGSVSIKCFYPP-TTVNRHDRKYWCRES---SRSCLTVVST---SGYRARGYQGRVTI
VDF-----PEQGIMLVNISQLTLADQGTYQCGIGLN-GKG--LSN---------R-----
------------------------------------------------------------
------------------------------------------------------------
---------------------------------V--------SLDISEGPNIPEE---AE
LFYV----------

PF07686 // ENSGT00530000063436_0_Domain_3 (555, 673)

-ELQGSVSMACDFGED-YASTRKF------------LCKME-KSGC
RNIIDTYGKIDSDFQGRILLSNEN-TEGAFSVMITQVDWED-AG---LYLCGVGSYGEYG
E---TKELD-LH

ENSGT00530000063436_0_Linker_3_4 (673, 682)

VYEGTKAAQ

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 795)

GKHTIFGVKGSSATIDCHYDPTK-----NYSLKYLCKWR
TTG----CARIIDNTGFLPGP---YEGR---VAMFDNPKNGT--FSIVLNQLSSRDEGFY
WCMTDDHRERRTSK

ENSGT00530000063436_0_Linker_4_5 (795, 813)

ELKIVE--GECGLTG---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 921)

KEEVQAEVGS--RVDLTCSYPCKYYS--
-YEKYWCKWSRDG--------CTPLTSSDQSHPGLDVSCDTANKTLILSLDPVTVEDQGW
YWCGVKHNGHYGETMAVSLQVDG-GKAANIS---------PELLDLEA------SNAAAA
-------------PDEAV--P------------QGRA-----------------NSD-A-
-------GVQRAAA-SE-SSEQS--SGSSTLALILGPIG--AA-LLVLAAAFAVFKYRQI
R--RSDLVSV----GSYRTNISMSDFE-NAREYGANDNVCMKQ---SQETQLGG-DEF--
-VTTTA--------NTESTAETKKAKR---------------------------------
-GSKEDA-DLAYSASLLTPSTTTQSPAGDSTAPAEAPPLWGGSV-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------SS

PF07686 // ENSGT00530000063436_0_Domain_1 (232, 336)

IFGPRQVTG
LLGGSVTVKCFYPR-TNVNRHDRKYWCKES---TRQCATVISS---NGYIAQDFAGRATI
TDF-----PEQGIFIMELSKLGLKDIGFYKCGIGLN-DRG--LSF---------EVKLDV
SQD--------------WEIYPTDNI-QKEL-SAF-LVLLSWLY----------KGTIKK
----KK--KRRSYAVMH-GS-------LT--QY-----------RTVQQTVPC--DIRQK
YMMLCA-V---IYPTVQCMWGGLVHNDAGLKSMVKVSRAMVEQDILNWSPKVPEG---AE
LYYK-----------

PF07686 // ENSGT00530000063436_0_Domain_3 (556, 658)

ELGGSVTMNCVFGTQ-YASVRKY------------LCKMG-KTGC
STVIDTYGNVNPTYKGRALLSPQE-TPGSFVIYMTQLRKED-SG---LYLCGVGEYG

ENSGT00530000063436_0_Linker_3_4 (658, 683)

ETV
D-FPKKHMS-PFVSPETAVPQG

PF07686 // ENSGT00530000063436_0_Domain_4 (683, 786)

RHTINGVIGGSVSVECRYDPRR-----NYTLKYLCKWR
KNG----CTQLITNLIMMIDS---YEGR---IVMHDNPKNGT--FTIIMNQLVAEDAGYY
WCMTD

ENSGT00530000063436_0_Linker_4_5 (786, 814)

GDVERKSSKELKIID--GQPGLTG---L

PF07686 // ENSGT00530000063436_0_Domain_5 (814, 913)

KEVNAVIGT--RVTLSCSYPCKYYS--
-YQKYWCKWNNRG--------CKPLVSYEQNQTSPAVNCDEENKTLYLTFNQVTQTNQGW
YWCGVSHSGHYGETMAVFLRVNG-GEPKNLPQGKNSQNLDPAIGSGK-RADF--PADS--
----SSPRYCED-PCRYRGEG------------PAREQPL----RIPEPDLLLPQIS-IK
S---HEHTRVLHIC-SFSSSQEH--DNSKVILSVLIPIA--VV-CLLLGTVFVVVKFKLL
K--RTELVSV----GSYRTNISMSEFD-NPRELGAKENAGINN---SQETQIGGVDEF--
-VTVPA--------NTESAEEPKVVKR---------------------------------
---------------------------------------------

----------------------------------------P-----PQASSTI-------
---------------------------------------------------------VLS
LQVTNRRAGWKMPVLLMVCLLQGSALTPPHRRPHFRCL----------------WNGPV-
--PSGAHLWA-----NESLTPFSP----LCLM-EETSI--------AAAGALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 343)

GPRLVSG
KPGGAVTIRCHYAP-LTINMHDRKYWCRLSPV-THICHTIVST---THYTHLRYRGRVAL
ADF-----PRRSLFVVTLAQLSPDDVGRYRCGIGNTNN-M--FFF---------SMNLTV
SAGPSG--SIP-TATPAATE-----LVTGSFGTASPV-ANGRTPGA--------------
----------------------------T--QTIERQGTGWAGV----------------
-----------------------------------------------------AG-----
----TPGTT-----A---------------------------------------------
------------------------------------EGRQTLGT-TGAGALGTDSQGAA-
S----VWAT-V------PIPES-------------------PASAIGGVSDTTEDVWVWD
PRG----SV--ANRAR---PS---EEAGET-TTEADGAEEET--ER--------------
--------VRTAPDVAAKVTGTRRPSTL----VSE----KWVQGILREA-----------
---TTVS-------------EPQALGSIEGTAPAAGVWTLGPT-----------------
------------SR-EMAS-EEG-TTQGDLD----------------------RPA----
-----GDSDPQATPSQAPAAG------------SMR--PW--------------------
-------GKGSPM--KSATPGEK--NKSWIL----IPVS--M-LFPVTLVALGLLQKKLR
R-KRM---SEETERTAGVTLIQMTYFL-ELSLQPD-QLPLIER-------KMLR-GDC--
-PP-QASL-----TVPERHPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------AG

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ALRVVPEVKVEG
MLGGSVVIECPLP-----EMHVRIYLCRTIVE-SGGCATVVSN---RNFVKKEFKNRVTL
ELC-----PDRNLFLVEMTELVESDSGVYACGAGMDTDRG--KTQ---------QVTLSV
HS----------DYGPFWEEEP-----MPEP--------PAWFRM---------PL---W
FQMPEHASSLEFISKV---------TTPA--QRTEAPPAHHASPTTS--ITHR--PRVYR
AS----------------------------------------SAATAQPTTLLPS-----
----ATA-SKTSAQEELLRLQTASYNHQTR-LHRQSSLNQGP------GPVSGME-DQ--
-----GFYILTPTILGLILLALL----GLVAKRVIQRRK-A-LS-RRVRRLAVRMRALE-
A---SQ------------RPR----------------VSQRPRT-----QNNVYSACPRR
PRG----VDAAG------------EG-A----APLPCPGA-----L--------------
-----------------------APPAPP--QVSETPWLHAP--SVKISCEY------VS
FYHQPAAKMEDTH--SDDYVNIPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDQDS-----PAKPR---------
-----------------------------------------------------------E
QKVSSQRTRWKI-LLLILCLLHGSSMTPPHRQPHSGEL----------------QAGSP-
--PSRTPLCT-----MEAHRASTP----PCCW-K-NSL--------TGANALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 343)

PRLVSG
EPGGAVTIRCHYAP-SSVNRHQRKYWCRLAPP-LWTCYTIVST---NHYTHRDYRGRVAL
TDF-----PQSALFMVKLFRLSPNDTGLYCCGIGDRND-K--LFF---------RMNLIV
SPGLPN--TTYAAAVPASGE-----LITASSGIGSTA-ANRSTPGV--------------
----------------------------T--QSLEGQGSEWDRT----------------
-----------------------------------------------------AP-----
----TTRISKTTVPA---------------------------------------------
------------------------------------NGRSTLRIIARTTAPGKSTREEG-
Y----IKTT-V------PTPES-------------------PASKSRSMFSTTQGAWVLG
AQN----SV--TSSAS---TS---EGGRTGTVPEAEEPQWET--E---------------
--------VSTSPGAPEKTTGTTQPSVL----ISE----PVTWETLQEA-----------
---TDDS-------------KQQLLYSSEEPSSDPGAWTLNAT-----------------
------------RM-QVAS-G---SIGRTLE----------------------NTG----
-----GES-SPPTPSQLSSWG------------PMW--TP--------------------
-------GKRSSM--KSVFTEGE--SNTWIL----TPVS--SVLALVLLAALVLLKRRPW
RT------SQKTERSPRITLSQMTHF------LPD-KLSDVGK-------SLQQ-GDP--
-PSAQASL-----TVLKKDSGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPVFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNGTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQTSVLVIDSR--NYVN------PNYKDRIRLRIP-GTGQLI
FTIVIDRLRLSDHGLYLCQAGDG-SNRD----------------EKNADLQVLE--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGKRDSAFEGRILLNPQD-KDGSFSVVITGLRKED-EG---RYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SQSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLNIPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGPQEA

------------------------------------MEGEI-----PTKV----------
------------------------------------------------------------
-LLWTLALEWPVHP----SPHFGSSLA--HRGSPPKSL---------------QQDVSL-
--PSRTQTCA-----KAMLTAFSS----LCWQ-ETLPF--------TD

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ANALKGPKLVSG
ELGGTVTIQCHYIP-MSVNRHQRKYWCRVGPP-RWVCLTIVSS---NYYTHHHYRGRVAL
TDF-----PQRGMFVVTLSQLSPDDVGSYRCGIGNENN-M--FFF---------SMNLTL
PTGGPS--SVP-----TAAE-----LITASIGTASLA-PDRCTSET--------------
----------------------------T--RAVEVHETEWDSV----------------
-----------------------------------------------------VP-----
----TLGRSKTTPAA---------------------------------------------
------------------------------------KGRQTPGI-AKTIAPSTGRRGAG-
S----MEAT-V------PFTGS-------------------PASPLRTTSDS-ASAGAWS
TGS----ST--TYRAG---TS---IEERVMATTEAYEPWEET------------------
---------------AGEVVEATRPSAP----ISG----SSAWKALQET-----------
---IPVS-------------MHQALDATEGTSPDAGVWPSEVP-----------------
------------GT-EMAS-MEK-STGGVLH----------------------ITA----
-----GDSGPQATPSQAPAAS------------TGR--SP--------------------
-------GKESSV--KRALGPGS--NMPKGGSVSPDHTSNHFSF----------------
-CVSA---VQEAGRAPGIALVQVTHML-EPHQD----QPHVQT-------KMLR-QDSAP
T---QTSP--------MCFEGPR-------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLCFLPV--------AG

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ALRILPEVKLEG
MLGGSITIECPLP-----QMHVRLYLCREMAE-SGGCATVVSN---KNFVKEEYKHRVTL
KPC-----PDKNLFLVEVTELTKSDSGVYACGTGMKTDRG--KTQ---------LVTLTV
YSVYPS--YPRPEYELFWEEEP-----MPEP--------PRWLHKFLHM--PV-PP---W
LQMPVHDSSFEFIPKV---------TTPA--ERTKAPPEIHSSPTTP--APHH--LRVSR
AS----------------------------------------SVAAAKSPTLLPS-----
----TTA-SKTSAPEGLLRPQTASYNYHTR-LHRQRAFHQD--------PVPGLE-DQ--
-----GFHILVPTTLALILLALL----GLLMKRVIQRRK-A-LS-RRVRRVAVRMRALE-
A---SQRPP-L------HRPH----------------------------------XCPRR
ARA----ADAEG------------QA-E----VPLPGLRA-----S--------------
-----------------------APPAAP--QVSEALCLHAP--SLKTSCEY------VS
LYYKPAAKAEDTD--SDDYVNIPCLTHLSSCPPGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHVRVYLCREMVG-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PHKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKVPPVHHSSPT-T--ITHR--PRVSR
AS----------------------------------------SVVGDKPPTFLPS-----
----TTT-SKISALERLLKPRTASYNHHTR-LHRQRALHYG--------SRSGRE-GQ--
-----GFYILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSRLPRS-----QNNIYSACPRR
ARG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWFHAP--SLKTSCEY------VS
LYHQPATQMEDSN--SNDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 335)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLG

ENSGT00530000063436_0_Linker_1_2 (335, 387)

IN-SRG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQTSVLVIDSR--NYVN------PNYKDRIRLRIP-GTGQLI
FTIVIDRLRLSDHGLYLCQAGDG-SNRD----------------EKNADLQVLE--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGKRDSAFEGRILLNPQD-KDGSFSVVITGLRKED-EG---RYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 792)

SPTVVKGVAGGSVAVLCPYNPKE-----SQSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWR

ENSGT00530000063436_0_Linker_4_5 (792, 812)

TTVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 910)

-PGNVTAVLGE--TLNIPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MELWLWLLCFLPV--------SGTLKILPEVH

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LDG
ALGGSIIIECPLP-----EIYTRMYLCRQMTN-PSICVTVVSN----SFVKDEYRSRVTL
KPC-----FDKNIFLVEVTKLTKSDNGVYACGVGTHTDRG--RTQ---------KVTVNV
HNEY----------KPFWEDEP-----TSGL--------PGWFDRFLNQ--QM-PN---W
FHEVTQATPSEFISKA---------TTPV--PKTEVPPIHQLSNTAP--ITHH--PQVSR
TS----------------------------------------LVVAVESPDFLPP-----
----TTV-SKTSAQEG-VRPLGASYSHHTR-LDEQRTRNHD--------PQTGRE-DQ--
-----EFHILIPSVLGLLLATLL----GLVIKRAIQRRK-A-FS-RSIRRLAARMRTQG-
G---SGRSP-A------QRPR----------------PSRRPRS-----QNNVYSACPWR
ARN----ADAAG------------QE-A----RPLPSAGA-----S--------------
-----------------------APSAPP--LVPEVSWIYAP--SLKTSCDY------VS
LYHQPAAHVEDTD--SDDYINIPSLTHLPSCLSGPRPSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TLKLREQKEVARRG
TEV-DYS------------------------------------------RLIAGT-LPRS
H------LRWKMPFFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLRPSSS----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

SRLVSG
EPGGAVTIRCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---SHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPFS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWIPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGSQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAAKSRSMSDTTEGVWG-G
TRS----SV--TNGVR---AS---KDRREMTTTKADRPKEDT--EG--------------
--------VRITLDVAKNVLGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYFGETTPAVGLWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEEE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRI---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MCLWLWLLCFLPV--------SGTLKVLPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 361)

LDA
ESGGSITIQCPLP-----QTDVRMYLCRQMTD-PRICTTVVSN----IFVKKEYKTRVTL
TPC-----LDKKLFLVEMTQLTESDNGVYACGVGLHTDLG--KTQ---------KITLNV
HDEY----------EPFWEDEP-----TPEP--------PPWFHRFLQE--HI-PP---W
FHEVEHDSPSEFTSEV---------TTSA--PRTE-GPVHQHSSTIP--VTSH--PRVSR
TS----------------------------------------PVTAAKSPAPLPA-----
----TTS-SKTSVQQA-IGPLGASYSHHTK-LHDQRTLHHS--------PQYGRE-NQGL
HIPVLEFHILIPTFLGFLLLVLL----GLVAKRAILRRK-A-FS-RRMGRVAMRIRGQE-
A---SRRLP-A------QRRG----------------APQRPRS-----QNNVYSACPRR
APM----PDGEG------------SA-E----ASLHSAPA-----S--------------
-----------------------APRDP--CQ----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLL-----------------LLTCLLAVFPGV--------SM

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

KSPIFGPQEVRS
VEGKSVSIRCFYPP-TSVNRHTRKYWCRQGT--SGRCSTLLSS---EGYVSEDYAGRANL
TNF-----PENGTFVMDIAQLTPKDTGHYKCGLGIS-SRG--LFF---------DVSLVV

ENSGT00530000063436_0_Linker_1_2 (361, 378)

NQG--------------

PF07686 // ENSGT00530000063436_0_Domain_2 (378, 533)

PQ--DDTQVYTEDLGKTV--TI-------------------NC
PFKRENAGKIKSLYRKC--QCQMLVIDTN--GYVN------EYYKGRIRLTPT-GTSQLT
FSVTINYLRPDDAATYICRTGHD-S-SN----------------DKNVVLEVRM--PEHE
LVYG-----------DLRGSVTFDCALRPV-EKDMAKY------------LCRVGKEQTC
EVLINTLKKRNPAFDGRIVKD----ENGLFSVS-AGLRXXX-XX---XXXXXXXXXXXXX
XXXXXXXXX-XXXX

PF07686 // ENSGT00530000063436_0_Domain_4 (675, 799)

XXTAIPNRPSVVKGVTGGSVTMLCPYNPKG-----SNSLRSWCHWE
EAN----CPPLVSTTGLVNKQ---YDGR---LALFEEPGNGT--YTVILNQLTTQDAGFY
WCQTDGDHRWSTTGELKV

ENSGT00530000063436_0_Linker_4_5 (799, 804)

VEG--

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

EPSLKV---PEHITAVLGE--TVKLSCHFPCKFYS--
-YEKYWCKWSNKG--------CQALPSEDEGPSQAFVNCNQKSQIISLTLNQVTKENEGW
YWCGVKQGHNYGETAAVHVTVEEK-G---KDV--D-------------PA----KA-NAA
SDVDVVEPSVR------KT----------------------GNKIIQDPRFGAEEKV-VE
ESGDQARGSRGSSD-SSXXXXXXXXXXXXXXXXXXXXXX--XX-XXX--XXXXX---XXX
--X-XXXX-X----X-XXXXXXXXXXX-X--XXXXXXXXXXXXX-----XXXXXXXXX--
-XXX-XXX--------XX----------------------XXXXXXXXXXXXXXXXXXXX
XSSKEEA-DLAYTAFLLQSNNMAT-QAQDRP--TEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------TLI---------------YMLTSCINIYHTVV--------SNS

PF07686 // ENSGT00530000063436_0_Domain_1 (230, 336)

SPIFGPKQVTG
LVGGSVTVKCFYPR-TSVNRHSRKYWCKES---TQHCSTIISS---NGYVARGFEGRTSI
IDY-----PENGLFTIEISNLVRRDMGPYKCGVGLN-DKG--LSF---------RVKLDV
SAA--------------PLLLEATEAYL---------RV-QWQH----------TMTANC
VESVQS--SPERLASLH-KSGHIVSLKPT--NYVNGAGPPSPNETGKIAIHVL--PPIN-
-------IVIKYVKECSAIWD--------------------SKMKDAASSILPEE---AQ
LF

PF07686 // ENSGT00530000063436_0_Domain_3 (543, 657)

YA-----------EQHGSVTITCAFGAR--ASGRNY------------LCKMT-KYTC
VNIIDTDGNIDQFYKGRVLLSNLQ-IPGSFNIIMTQLQKQD-SG---LYLCGTGNY

ENSGT00530000063436_0_Linker_3_4 (657, 678)

GAEG
E---TKKLD-IHVYEEV

PF07686 // ENSGT00530000063436_0_Domain_4 (678, 796)

LVSKQQPILNGVQGGSVSVECHYEPKE-----NTTIKSWCKWK
ENE----CTVLINNLGDVRDD---YEGR---IVMHNSPENGT--YTIILNQLHNGDEGFY
WCMTSGEQERISSTE

ENSGT00530000063436_0_Linker_4_5 (796, 814)

LKIVQETGQPSLSV---D

PF07686 // ENSGT00530000063436_0_Domain_5 (814, 913)

NEIHAVAGS--PLTITCTYPCKYAD--
-YEKYWCKWKNTG--------CEPLIASEESQAGLVVSCDKGSRILSLNFDQTSLSDQGW
YWCGVRKGGHYGETYATYLQVQG-VLIRGTTLLRN----------------AEEPS----
-------RPNEE-PSDVV--S------------QNRNIPLNNANKIPKITWEDSGTI-IC
N--LEAGGNTKSIQ-LFSSHKES--KHSTILLSVLLPLG--II-LVLLATAFFVVKFRLF
K--HSDLVSV----GSYRTHISMTDFE-NARQYGAKDNVCMAE---AHETQIGDKDDY--
-NITTS--------SPKEAGKSKKAKR---------------------------------
-NSKEDV-EMVYTTFLLNSENIPPRGSQQQ---------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MCLWLWLLYFLPV--------SGALKVLPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LNA
EWGGSITIKCPLP-----QIHTRMYLCRQMTD-PQICTTVVSS----SFVKKDYKARVTL
TPW-----LNKKLFLVEMTQLTESDNGVYACGVGTNTDLG--KTQ---------KIILNV
HDEY----------EPFWEDEP-----TTEP--------PPWFHRFLQE--HI-PS---W
LHEVGHAS-----SEV---------TTSA--PRTE-APVHQPSSTIP--ATHY--PRVPR
TS----------------------------------------SVTAAKSPTLLPT-----
----TTA-SKTSAQQA-LGPLGASYSHHTK-LHGQRTLHHS--------PQYERE-DQGL
HIPVLEFHILIPTFLGFLLLVLL----GLVVKRAILRRK-A-FS-RRMGRVAMRIRGQE-
A---SRRFP-A------QRRG----------------ALQRPRS-----QNNVYSACPRR
APP----PDQEG------------SA-E----ASLLSAPA-----S--------------
-----------------------APPDP--SQVLEAPWCHTP--PLKTSCEY------VT
LCHQPAVNVEDTG--SDDYINIPGPRHLPSCPPGHRPSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGEA-----PTKPREQ-------
------------------------------------------------------------
-KVTNQEAGWKTPLLLTLCLLQGSSSAPPHKSAALTLL--------------DSTS--E-
--GCRLPLSPLGPSSGPGKHSSSP----LCWW-KKADL--------A

PF07686 // ENSGT00530000063436_0_Domain_1 (228, 361)

AANALKTPKPVSG
ELGGAVTIKCHYDP-TPVNRHQRKYWCRLGPP-KWICRTIVST---NYYTHRSYHGRVAL
EDF-----PQSSLFVVRLSQLSPADEGYYHCGIGNNND-M--FFF---------SVNLTV
NAGPPS--TIP-TAAPAASE-----LTMRSSATASPV-ANRWTPGT--------------
----------------------------T--RTIEGQGTGWDRV----------------
-----------------------------------------------------VP-----
----TPGASKTTSSA---------------------------------------------
------------------------------------KGGQVPGI-TRALAPRTGSWVEG-
C----IRAT-V------LTPES-------------------RTSKLTVTLNTTEDVSVWD
TTS----SV--ASRDR---VS---KEERKMTTPKVDGPTEET--RR--------------
--------VRLPPNPTWNVTGTIRPSTL----VSE----KRAWETLQGAT-S--------
---TSVS-------------KQPTLGSTEETTPAAGVWTLGTT-----------------
------------NI-EMET--EG-STEGDLA----------------------SAA----
-----ENSGPQATPSQFPAAG------------PLR--PH--------------------
-------GKGSSV--ESSLPEEN--GVSQIL----PPIS--TVLPLVILLALVLSQKKLW
R-KKACEIGSEAERAPRVTLTQMTRFW-ELSFTPD-QLPLMER-------KMLQ-DGS--
-CHTHVGL-----PITAKDPRP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LM--------SGALKILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

ELEG
ALGGSVVIECPLL----EKGQVRMYLCRQMAN-PGICSTVVSS----NFIKDEYRHRVTL
MPC-----SDRKLFLVEMTGLTERDSGVYACGLGIHTDKG--KTL---------KVTLSV
HNE----------YEPFWEEEP-----MSES-------QSLWLHKLLQQ--QM-PS---W
LEMGALPFL---PSSA---------DATA--ERTEAPPVQRSAAATP--TAHR--PQTPG
AS----------------------------------------LAAAAKPPPLLPS-----
----TTA-SKASAQEGLLGPQEASYNHRTW-LHKQRDRSRGHLP---KAGRARAR-DL--
-----GFHILIPSALGLLLLALL----GLVLRRALQRRR-G-EQ-RRGTGPSARGAGAG-
A---GAGGP-A-----RERER-------------ERERGAGRRG-----RGGARGSSSLT
PPA----RSPLQ--------------------------TD-----P--------------
-----------------------PASLCP--QVPDAPWLPVP--SLKTSFEY------VT
ICHQPAARREDAE--SSDYINIPSLT----CPPGPRLWRQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TLKLREQKEVARRG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVAN-RRAGWKMPFFLILCLLQGSSFALPQKRAHPRWL----------------WEGSL-
--PSRTHLQT-----MGTLMPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIHCRYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------KGRQTPGA-TRLAAPGTGSWAEG-
S----ITVP-A------PIP-------------------ESSASKSRSMSNTTEGVWG-G
TRS----SV--TNRAR---AS---KDRREMTTTKADRPREDT--EG--------------
--------VRITLDAAKNVLGTIRPPAL----VSE----TLAWEILPRA-----------
---TPVS-------------KQQSLGYVGETTPAVGGWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-STAGDLD----------------------AAT----
-----GDRGPQATLSQPPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SNSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQAAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------NPASAPSK----------------------------------
---------------------------------------------------PRSQ-MCFL
QVAN-RRAGWKMPFFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLRPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

SRLVSG
QPGGTVTIRCHYVP-SSVNRHQRKYWCRLGPP-RWICQTIVST---SHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSDNA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAAKSRSMSNTTEGVWG-G
TRS----SV--TNGAR---AS---KDRREMTTTKADRPREDT--ER--------------
--------VRITLDAAKNILGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYVGETTPAVVLWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----EDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRI---SQEAE---RVTLIQMTHFL-EVDLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNLGP--------------------------------------
---------------------------------------------

------------------------------------MDQDS-----PTKPKEQKVTWLSL
G-SLGLTLRWVVFAAAAVTCALRVRRLFSEAREDLAGEGRCQAPAFIFCILFSEKY---T
QFEPLERTEPAH-IRYRTHSCPGSSMTPPHRRLHSRGL----------------PAASP-
--PSRTHLCS-----LEADTASIP----PCCW-K-NSL--------TDANALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 343)

PRLVSG
KIGGAVTIHCHYAP-SSVNRHQRKYWCRLGPP-LWICSTIVST---NHYTRHDYRGRVAL
TDF-----PQNGLFMVKLFQLSLNDTGLYHCGIGDRND-M--LFF---------RMNLIV
SAGPSN--TTSAA-APTSGE-----LITVSPGRAS-A-TNRWTLGV--------------
----------------------------T--QILEGQGSEWDRT----------------
-----------------------------------------------------DL-----
----TTRISKPAASG---------------------------------------------
------------------------------------NERQTPRT-ARTMVPGTSSSEEG-
S----IKAT-V------PTLES-------------------PASKSRSMFSTTQGVWIWG
TRN----SA--TASAS---TG---EGREKGTAPEADGPQEET--E---------------
--------VSTSPEALGKTTGANRLSVL----ISE----HVTWETLQEA-----------
---TEAS-------------KQQTLYSVEESSPAPNAWIVNAT-----------------
------------HT-QMAS-E---SLDWSLE----------------------NTG----
-----GES-RPPTPRQLSSEG------------PMW--TP--------------------
-------GKESSM--KSAFTEKE--SNSWIL----TPVS--TVLALVLLVSLVLFKRRLQ
RKTT----FQEAERPPRITLIQMTHF------LPD-KLPDLGK-------NLHQ-GDL--
-PPAQASL-----SVLEKD-----------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTSL-----------------FLTCLLTIIPAV--------FMKSPIFGPQEVST
VE

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GNSVSIKCYYPA-TSVNRHARKYWCRQNN--RGSCNTLISS---GGFVSKDYTDRANL
TNF-----PEDNLFVVDIKHLIQNDTGKYKCG

ENSGT00530000063436_0_Linker_1_2 (333, 392)

LGIN-NRG--LSF---------DVSLEV
NKG--------------PGLSNNTQVYREDW

PF00047 // ENSGT00530000063436_0_Domain_2 (392, 500)

GSNV--TI-------------------IC
PFKAENTQKKKSLCKKT-GQDCVLVIDST--GYVS------PNYKDRAHFKLQ-GTSQLK
FSITINRLRPEDAGAYACK

ENSGT00530000063436_0_Linker_2_3 (500, 539)

AGEE----K----------------ERDVDLQVVK--PE

PF07686 // ENSGT00530000063436_0_Domain_3 (539, 674)

PG
LIYG-----------DLRGSVSFECALGPE-KANVPKL------------LCRVSTGEAC
DLVINTQGERAPGFEGRILLTSTD-KDGSFSVLITGLRKED-AG---LYLCRA--DGQLV
EGRPTQAWQ-LFV

ENSGT00530000063436_0_Linker_3_4 (674, 691)

NEETSIPHSPSVVKGVP

PF00047 // ENSGT00530000063436_0_Domain_4 (691, 784)

GGSVAVLCPYNPRE-----SNHLKYWCRWE
KTQ-KGRCPLLVESEGLVNPQ---YEGR---LALYEEPGNGT--YTIILNQLTAQDAGFY
WCL

ENSGT00530000063436_0_Linker_4_5 (784, 804)

TNGDSSWRSTVELKVVE--G

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

EPNLQV---PRNVTAWLGE--TLNVPCHFPCKFYS--
-HEKYWCKWSNRS--------CLTLPSQDEGPSQAFVNCNQNSQVISLTLNSVKKADEGW
YWCGVKQGHLYGETAAVYVTVEEG-TKGESPR--N-------------ESHDASQA-SAV
PNGEVVEPNVR------ES----------------------GNKVVQVPRLVVEE-----
DSEDPAGASRVNTN-PSSAEGQG--GGSPVLVSTLVPLA--LV-LGLGAVVVGVLRARHR
--KNVDRVSI----RSYRTDITMSDFD-NSRDFGANDNMGASPI--SRETSFRGKDDF--
-MATTEST--------MESEEPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQSNNMAA-SIQDGP--REA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLS-----------------VLVSLLAIFPVV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

PKEVSA
VEGSSVSITCYYPP-SSVNRHTRKYWCRQGA--SSSCMTLISS---QGYVSQNYAGRANL
TDF-----QELDAFVVNISHLSQQDSGHYKCGLGIN-TRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 391)

NF---------DVNLKV
SQD--------------PRLLNNTDVYTED

PF07686 // ENSGT00530000063436_0_Domain_2 (391, 533)

IGSTV--TI-------------------NC
PFKSQNAITKKSLCKKT-DESCVLVIDSN--NNVH------PSFIGRVRLVVQ-GTGQLV
FGIVINQLRPSDAGMYVCQAGEG-PSSD----------------KTNVDLQV

ENSGT00530000063436_0_Linker_2_3 (533, 540)

LE--PKP

PF07686 // ENSGT00530000063436_0_Domain_3 (540, 661)

E
LVYG-----------QLRGSVTFDCALGPE-VAHLQKF------------LCRVNKEKSC
DVIINTLGKRDPAFEGRILLSTKDTTDGHFSVQITGLQTGD-AG---KYLCGAHSDGQPQ

ENSGT00530000063436_0_Linker_3_4 (661, 681)

EGWPLQAVQ-LFVNQETIIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 789)

QTPTVVKGVTGGSVAVLCPYNPKE-----SKSLKNWCRWK
GEN-TGRCPPLVDSQGLVQNK---YNGR---LAVYDEPGNSS--YTVILNQLTTQDAGFY
WCLASSDA

ENSGT00530000063436_0_Linker_4_5 (789, 814)

RWTTMVEIKVVDG--EPSLKI---S

PF07686 // ENSGT00530000063436_0_Domain_5 (814, 920)

KNTTAALGD--TVKLACHYPCKFYS--
-YEKYWCKWSKQG--------CQALPSQDEGPSQAFVSCDQDSRLVSVTLQSITKEDEGW
YWCGVKQGQSLGETAAVYVTVVEK-ARGSGAV--N-------------VDPP---V-NSA
PEEEVVQSHSE------EFE----------------------NKAVLNPRLLVEEKV-AE
DPENQAGGNRASID-GSSSAGQG--GSSKVLLSTLVPLG--LV-LALGTVAVWVARVRHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFGGNDNVGASPD--TQETVLEGKVEA--
-MANIEST--------RDTEEPKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSNIAT-QAQDKP--SEA---------

------------------------------------------------------------
------------------------------------------------------------
--VTNQKAGWKMPVLLVLCLLQGSALAPPHRRPHLRWL----------------WVGSL-
--PSRSHLWA-----KETLIPSSP----LCWR-EARSI--------AAASA

PF07686 // ENSGT00530000063436_0_Domain_1 (232, 345)

LKGPRLVSG
ELGGAVTIQCHYDP-LVINKHQRKYWCRLNPL-TWICHTVVST---NNYTHPRYHGRVAL
ADF-----PKRGLFAVRLSQLSPEDAGRYRCGLGNRNH-M--VFF---------SMNLTV
SAGPAS--TSP-TATPAAGE-----LVRGPFGRTSVA-ANGWTPGT--------------
----------------------------T--QTIARQGTGWDRA----------------
-----------------------------------------------------AL-----
----TPGTRESAASA---------------------------------------------
------------------------------------KGRQTSAT-TRAAAPGTGSRVEG-
S----VRAT-V------PIPES-------------------PASTIGGVPTATEGVWVWG
TSS----SV--ANGAR---AN---EEGRETTTPEAALPGEET--ER--------------
--------LRTALDAAGKAIGTIRPSTL----VSK----QWAWETLREE-----------
---TSLS-------------KPQAPGSVEWLTSAAGVWTMDPT-----------------
------------SV-EMAS-AEG-SAEGDLD----------------------VPA----
-----GDSSARATPIQAAGAG------------PLR--PP--------------------
-------GRESSM--KTASPEGK--NVFRIL----TPVS--TVLLPLTLVALFLLQRKLQ
R-KST---SQETGRAAGGILTRMTHFL-ELSLQPG-QLSCVER-------KMLQ-DDS--
-PLIHASL-----TVLERDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPVFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNGTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQTSVLVIDSR--NYVN------PNYKDRIRLRIP-GTGQLI
FTVVIDRLRLSDHGLYLCQAGDG-SNLD----------------EKNADLQVLE--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGKRDSAFEGRILLNPQD-KDGSFSVVITGLRKED-EG---RYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SQSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLNIPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGPQEA

------------------------------------MKQEA-----PTKPGEQKVRWGFS
KALPCGPARRV--------GAQSVLSELRSHSEKVPSLGLCHPLQLLSHFSLACYLC---
LQATCRRTGRIL-HLVFLCLLHGSSLTLPQRRPHFRQQ----------------CEGSL-
--PFKIHLRN-----MT---TCTP----PCWW-E-E-----------TSGALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 358)

PSLVSG
EAGGAVTIQCHYAP-SSVNRHQRKYWCRLEPS-LRVCRTIVST---NHYAHRDYCGRVAL
TDF-----PRRGLFTVKLFQVSLDDAGQYRCGIGNRNN-A--LFV---------GVTLNV
SAGPSN--TIYTA-PPDPGN-----VTLASFGTTSPI-ANKWTSAA--------------
----------------------------T--QPLEGQASEWDSK----------------
------------------------------------------------------------
----------ATPLA---------------------------------------------
------------------------------------KGRETPGT-VQAAASGAGSRVEG-
S----IKTT-V------PTPES-------------------PALKLRSMPTTTEGVWIWG
TQS----SL--TKTAS---TS---EHGRKKTSTEDERPGEET--E---------------
--------VRVILDTARKTTGTIRPSTL----SSE----HVARVTLPEG-----------
---TVIS-------------KQQMLASKATSSSAPGAWTWGSL-----------------
------------SI-EASV--EG-SSDGSLE----------------------NTA----
-----GESRLPGMPSQPPAEG------------STS--SP--------------------
-------GKGPSM--KSAFPEEK--SNSWIL----TTVS--TILSLVLLLTVVLLQRRFW
RRRSC---ELKAEREPRVTLIQVIPFL-NPNLLPD-QLPDVGR-------NFLT------
--------------VLEKNLAL--------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TLKLREQKEVARRG
TEV-DYS------------------------------------------RLIAGT-LPQS
H------LRWKMPFFLILCLLQGSSFTLPQKRPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLRPSSS----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIRCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---SHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWIPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGSQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAAKSRSMSGTTEGVWG-G
TRS----SV--TNGVR---AS---KDRREMTTTKADRPKEDT--EG--------------
--------VRITLDVAKNVLGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYVGETTPAVGLWTLGTPAAGV------------W
T-LGTPAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSS--GGPISVSS--PTP---------SL--TQGALL-----------LV
C-VSA---AQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----TMLS-----------------LLVFLLAAFPVV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVSA
MEGSSVSIMCYYPS-TSVNRHSRKYWCRQGA--KGSCTTLISS---GGYVSKDYVGRSSL
TNF-----PDLGAFMVNITHLSQEDSGHYKCGLGVS-N

ENSGT00530000063436_0_Linker_1_2 (339, 388)

RG--LNF---------DVSLEV
SQD--------------S-LLPNTDVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 533)

TVDMGKTV--TI-------------------RC
PFRSENADKKKILCKKT-DQSCELVINSN--REVG------PSFQGRVSLAIQ-GTDQSA
FNVVINQLRTGDAGMYICQAGED-PSSD----------------KKNVDLQVLK--PEPE
LVYG-----------QLRGSVTFDCALNPG-VVNLPKF------------LCRVNKNKGC
DVIVNTLGRRDPAFEGRILLSDTVTADGHFSVLITGLQTGD-AG---EYLCGAHSDGEPQ
EGWPLQAWQ-LFVNQETIMPH

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 798)

VPTVVKGVTGGSVTVLCPYDPKD-----SKSLKYWCRWD
GER-NGRCPLLVESQGKVQEE---YEGR---LALFEEPGNGF--YTVILNQLTTQDAGFY
WCLTSGDTHWRTTVEIK

ENSGT00530000063436_0_Linker_4_5 (798, 813)

VADVAGEPSLKV---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 912)

SKNTNAVLGQ--TLKLYCHFPCKFYS--
-YEKYWCKWSNQG--------CQALPSQDEGPSQAFVSCDQNSRLVSMTLQSVTVEDEGW
YWCGVKQGQTFGETAAVYVAVEEK-AKGAGA------------------INP-TAA-NSA
PEEEVVKPQVE------NK-----------------------AVQNQNPRLFVEERV-VE
NSGNQASGGRASVD-ASSSEGHS--GSSKVLLSTLVPLG--LV-LALGTVAVWVARARHR
--KNVDRLSI----RSYRTDISMSDFE-NSRDVGGHDNMGASPV--TQETVLEGKVEV--
-MDNTEST--------KDNEEPKKAKR---------------------------------
-SSKEEA-DMAYSAFVLQSNNIAT-QAQDGP--KDA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------SGAV

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 361)

KILPVINMKG
MLGGSITFKCPLP-----EMYTRIYLCREIAA-SSMCVTVVSS---RKYVKKEYTNRVTL
NMS-----KDKKLFLVEMARITENDSGVYACGVGTNTDRG--KTQ---------QIILNV
SXXXXX--XXXXXXXXXXXXXX--------X---------XXX-X-XXX--XX--X----
XXX--XXXX---XXXX---------XXXX--XXX--XXXXXXXXXX-X-XXXX--XPVSR
-A----------------------------------------SVTADKAPILLPS-----
----TKA-SKTSAQEEQVWSQPASNIYQTR-LHRQ-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLS-----------------LLVSLLAVFPVV--------STKSPVFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 336)

PEEVNA
VEGSSVSIKCYYPA-TSVNRHTRKYWCRQGA--SGSCITLISS---GGYVSKDYVGRSNL
TNF-----PEIGAFEVNISPVSREDSGHYKCGLGI

ENSGT00530000063436_0_Linker_1_2 (336, 388)

N-TRG--LNF---------DVGLEV
VKD--------------PRLLNNTEVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 533)

TMDLGRTV--TI-------------------TC
PFRSENGGKKKSLCKKT-GQSCELVIDSD--KNEN------PSFAGRVRLVIQ-GTDQEV
FSVVINQLRNRDAGMYVCQAGED-PSGD----------------TKNIHLQV

ENSGT00530000063436_0_Linker_2_3 (533, 539)

LE--PE

PF07686 // ENSGT00530000063436_0_Domain_3 (539, 659)

PE
LVYG-----------QLRGSVTLDCALGPE-MANVQKF------------LCRVNKDKSC
DVIINTLGKRDPAFEGRILLTPRDPSDGHFSVLITGLQTGD-EG---EYLCGAHPDGV

ENSGT00530000063436_0_Linker_3_4 (659, 681)

PQ
EGWPLQAWQ-LFVNQETPIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QTPSLVKGVTGGSVAVLCPYDPKE-----SQSFKYWCLWK
GEK-NGRCPLLVESQGLVQEE---FEGR---LALYEEPGNGF--YTVILNQLTTQDAGFY
WCLTNGDTRWRTMVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVDGMREPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 918)

-PKNTTVVLGQ--TLKLDCHYPCKFYA--
-YKKYWCKWSNQG--------CRALPSQDEGPSQAIVGCDQNNQKVSLTLQSVTKADEGW
YWCGVKQNQTFGETVAVYVAVEEA-ARGES-R--N-------------PLNP-VIA-NSA
PEEEVV-----------------I-----------------ENKAVPN------------
----------------PSSQGQS--RSSKVLLSTLVPLG--LV-LALGTVAVWVARARHR
--KNVDRISI----RSYRTDISMSDFE-SSRDFGANDNMGASSV--TQETVLEGKVEA--
-MANAEST--------TDTEEPKRAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSSIAA-QAQDGP--KDT---------

------------------------------------MDGEA-----TVKPGEQKEVVRRG
REV-DYS------------------------------------------RLIAGT-LPQS
HVTS-RRAGWKMPLFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRA-----MGTLTPSSP----LCWR-EESSF--------AAPNSLKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 345)

SRLVSG
EPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NQYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENN-M--LFL---------SMNLTI
SAGPAS--TLP-TATPAAGE-----LTMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRQTPGA-TRPAAPGTGSWSEV-
S----VKAP-A------PIP-------------------ESPPSKSRSMSNTTEGVWE-G
TRS----SV--TNRAR---VS---KDRREMTTTKADRPREDI--EG--------------
--------VRIALDAAKKVLGTIGPPAL----VSD----TLAWEILPQA-----------
---TPVS-------------KQQSQGSIGETTPAA-------------------------
------AADVWTSM-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWG--PP--------------------
-------GKESSV--KRTFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLW
R-RRT---SQEAE---RVTLIQMTHFL-EVNPQPD-QLPHVER-------KMLQ-DDS--
-LPAGASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------MDGEA-----PPKSRE--------
------------------------------------------------------------
PKVANRRAGWKKPLLLILYLLQGSSLAPAPRGSHLRSP----------------LQVS--
--SFRTHLCA-----METLTPSST----LCWQ-EAHSF--------TAAHSL

PF07686 // ENSGT00530000063436_0_Domain_1 (233, 345)

KGPKLVSG
KPGGAVTIQCHYPP-VSVNKHQRKYWCRLGP--RWICYTIVSS---YHYTHRLYGGRVAL
ADF-----PQRGVFVVTLSRLSLDDVGSYRCGIGDRNN-M--LFS---------SMNLTL
SAGGPS--TVP-TATAAAGE-----LSTASRGTASMA-AHRWTPGT--------------
----------------------------T--PAVEVQGTEWETV----------------
-----------------------------------------------------AP-----
----TPGSSKTTPPA---------------------------------------------
------------------------------------KGRQTPGT-ARTEAPGTGSQGAG-
P----TEAT-A------ASPES-------------------PASTIRSMPNATDGAWGWG
PRS----SV--TTRAE---IS---KDGGVMTTTEAAKPTAET--ER--------------
--------VRVDLNTTGEVTGATRPSAV----VSG----SLAWETLQEA--T--------
---SPVS-------------KQQALDATEGTSPATGMWTLGAT-----------------
------------SV-EAAT-VGG-GTDGDLD----------------------IAS----
-----GDSGPQAMPSQAPAAG------------PGR--LP--------------------
-------GKGSSV--KSALPEEA--SSSRIL----TLVS--TTLAVLLLVALALLQRKLL
FCVSA---AQKAERAPGITLVQMTHVL-ELHQDP----PCLEG-------KMLH-GDS--
-RAAQPRP-----IVPERDPEP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MSLF-----------------FLACLLAVLPVV--------SM

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

KSPIFGPQEVSR
VEGSSVSIKCFYPA-TSVNRHSRKYWCKQGA--RGRCTTLIS----DIYFSKDYEGRANI
TDF-----PEHNMFVVDIGHLTQNDTGHYKCGVGIV-NQG--LYF---------DVNLEV

ENSGT00530000063436_0_Linker_1_2 (361, 381)

IQG--------------PGL

PF07686 // ENSGT00530000063436_0_Domain_2 (381, 533)

QNGIRVYTADVGKKV--II-------------------NC
PFTSENAMQRKSVCKKT-GKQCVLVTDST--GYVS------PDYSNRAEITIQ-DTSQLS
FSFIINRVRLSDAGKYVCQAGDD-SRGD----------------KSNVDLKV

ENSGT00530000063436_0_Linker_2_3 (533, 558)

LK--PEPE
LLYG-----------DL

PF00047 // ENSGT00530000063436_0_Domain_3 (558, 653)

RGSATFDCTVDPE-MARLPKF------------LCRVNKDKAC
EVVINTLGTRAQAFDGRILITLKN--QGSFSVHITGLRKED-AG---SYLCG

ENSGT00530000063436_0_Linker_3_4 (653, 691)

AHSDGEPQ
EGWPMQAWQ-LFVNEETTIPRIVSVMKGVV

PF00047 // ENSGT00530000063436_0_Domain_4 (691, 784)

GGSVAMPCPYQPKD-----KNSQKYWCRWD
E-Q-NSGCPQLVSNEGLVKEQSKPYEGR---LVLHEEPGNGT--YTVILNQLTTKDAGFY
WCL

ENSGT00530000063436_0_Linker_4_5 (784, 804)

TSGDTRWWFTVELKIVEG-R

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

EPNLKA---PEKAIAWLGD--TLKVPCHSPCKFFS--
-YEKYWCKWSNKG--------CKVLPSQNEASRQASVNCDPNNQLTSLILNPVTKEDAGW
YWCGVKDGPQFGDTVAVYVEVKEK-AKASHDV--S-------------QV----NA--AA
PGKEVIEPRVK------VIEN----------------------QVIKDPSLFAEDKP-VK
DSGKPEDRSKASAD-TGSSAGQG--GSSTVLVSTLVPLA--LV-LALGAMAVAVVRARHR
--RNVDRVSI----GSYRTDFSMTDLE-NSRDFGTNDNMGASTITITQETSLGGEDEL--
-TAT--------TEDTVETQEPKKAKR---------------------------------
-SSKEEA-DMAHTAFLLQANNMAT-NVQDGP--SEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHVRIYLCREMVG-SGTCGTVVST---TNFIKAEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVIRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVVGDKPPTFLPS-----
----TTT-SKISALERLLKPRTASYNHHTR-LHRQRALDYG--------SRSGRE-GQ--
-----GFYILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSRLPRS-----QNNIYSACPRR
AGG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSSAPSGIGS--RGPTGRPQPWAGTRVR
LP-APPPRSGERV--SQQLLGPEPNKLF--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MKLF-----------------VFAILLTVLPAV--------ITKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 343)

PQDVSS
VVGNSVSITCYYPA-TSVNRHTRKYWCRKGA--SGLCTTLISS---NGFISTEYAGRAQL
INF-----PENNTFVINIAQLTQDDTGSYKCGLGTS-NQP--

ENSGT00530000063436_0_Linker_1_2 (343, 388)

LFF---------DVSLEV
SQV--------------PEFPEDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TEDLGRTV--KI-------------------EC
PFKTVNSPKKKSLCKKI-GQTCELVIDSN--KNVN------PNYKGRVNLNLAGGTSASK
FIVTITNLRRSDTGLYVCQAGEG-SNAD----------------IKNADLQ

ENSGT00530000063436_0_Linker_2_3 (532, 559)

VLE--PEPE
LVYR-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 656)

ASATFDCALGSE-VADLPKY------------LCRMN-KETC
DVIINTKGQRDSAFEGRILLTPKD-DNGHFSVLITGLRKED-EG---HYLCGASD

ENSGT00530000063436_0_Linker_3_4 (656, 683)

SGLPQ
EGWPIQAWQ-VFVNKESTMPTT

PF07686 // ENSGT00530000063436_0_Domain_4 (683, 798)

RTVVKGVTGGSVAITCPYNPKD-----SGSLKAWCRWE
ADG-NGRCPVLVESHGTVNEG---YEGR---LALFDQPGDGT--YTVILNQLTTQDAGFY
WCLTDGDSRWRTTVELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VSEATGKPNLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

TPQNVEAVLGE--TLTLDCHYPCKLYS--
-HDKYWCKWSNGG--------CHTLSS---QARQSSVSCDPNNQLVALTLNPVEKEDEGW
YWCGVKQGQTYGETTAIYIAVEG---KGSRQV--S-------------AADANARA-NAA
PEEEVGEFSAS--------E---I-----------------ENKAVPDPRLLAEETG-RE
SVGDQVQDSRASVD-AGSTDGQS-SGSSKVLFSTLVPLG--LV-LAVGAVAVWVARVRHR
--KNVDRMSL----NSYRTDISMGDFK-NSRDLGGNDNMGISPD--THETVLEGKDEV--
-VTTTEVA--------IEPEESKKAKR---------------------------------
-SSKEEA-DLAYSAFLLQTSNIAA-QVHDGP--RDV---------

------------------------------------MDGQA-----PTTPGG--------
------------------------------------------------------------
QKVANQRAGWKMQVALILCLLQGESQTAQRQSLQSQWQ----------------QANTP-
--QSSIRVWS-----WIGHDTPSP----ET---LLSLP--------AAANALKGPRLVSG
EP

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GGAVTIQCRYTP-TSINRHQRKYWCRLSPL-TWLCHTVVST---NHYTHGRYRGRVAL
ADF-----PHRGLFVVRLTQLSPEDGGSYRCGIGNGND-M--LFL---------SMNLAI
STGMGSPSPSP-GATSAASE-----RLRRAFGTASPA-ANRWAPGT--------------
----------------------------T--QTRERQGTEWGRA----------------
-----------------------------------------------------AL-----
----TPETSKRTASA---------------------------------------------
------------------------------------KGMQTPGT-PGLVAAGTVSQVES-
S----SWAT-I------PIPES-------------------PASAVGGMPDTAERD--WG
TRS----SA--TNRAG---AR---EEGRET-TTEANRLREEA--ER--------------
--------VRIALATDWTVIKTTGPSTL----ASE----KRVWETRQEP-----------
---SLVS-------------TPPALGSIEGTTGAAGVRAWGPT-----------------
------------ST-EISS-AEG-STEGDLD----------------------MPA----
-----GGSGPQTAPSQDPCCL---------------------------------------
------------H--SSASPEEK--NISRML----TPVS--TVLCPLALVALVLLQRKLQ
R-KRT---SQETEKAPGVTLIQMTHLL-ELSLQPD-QLPHVER-------KILQ-EGS--
-SPACATM-----RVPERDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPWLWLLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 357)

KVEG
ELGGSVTITCPL-----PETHVRMYLCREMAE-SRACATVVST---NNFIKNEYKGRVTL
TQY-----PHKNLFLVKVTELAESDSGVYACGAGINTDRG--KTQ---------KVTLIV
RSE----------YQPLWKEQP-----ASET--------PNWF--------HV-PY---L
FQMPAHASSSKSVPRV---------TIPV--QRTKVPPVHHPSLTTQ--IIHR--PRVSR
AS----------------------------------------SVVADKPPTLLPS-----
----TTA-SEISAPGVLLKPRTASHNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTVLGLFLLALL----GLMVKRAVQRRK-A-LS-RRARRLAVRMRAME-
S---SQPPR----------------------------GSQQKRS------QNIYSACPRR
ARG----ADAAG------------NG-E----TPVPGSRA-----P--------------
-----------------------SSPALL--QVSESPWLHTP--SLKTSCEY------AS
LYFQPTAKMEDSD--SNDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQTSVLVIDSR--NYVN------PNYKDRIRLRIP-GTGQLI
FTVVIDRLRLSDHGLYLCQAGDG-SNHD----------------EKNADLQVLE--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGKRDSAFEGRILLNPQD-KDGSFTVVITGLRKED-EG---RYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLNIPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEE-KVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGLQEA

------------------------------------MSKGKVTLLAVTKPSVPTLESGQS
SSFPGQAA-------------LPALSTVR-----------FHSESLLTRLPWVSCLCFQI
LQVTSQTTRWEI-FL-LLCLLHGSSMTPPTRKPHFRWL----------------QAGSL-
--PSKTYLCT-----MASNTS--S----PCWW-P-E-----------NASTLRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 359)

PRLVSG
EPGGTVTIQCHYVP-TSVNRHQRKYWCRLEPP-LWICRTIVST---NHYTHHDYHGRVAL
TDF-----PHSGLFVVRLFQLSLGDMGPYRCGIGDRNN-M--LFF---------NMNLTV
FAGPSS--TISAA-SSAPGQ-----FITVSFGITAPA-ANKWTLGT--------------
----------------------------T--QFLEGKGSEWDRI----------------
-----------------------------------------------------AP-----
----TTVTSKIIPSV---------------------------------------------
------------------------------------KGRQTPRT-TRTTVLETSSREVG-
S----VKAI-V------PTAES-------------------PASEPRSIPTTLESVWIWG
TRS----SV--TIRAS---KS---EGGRTKTTSETKRPQEET--E---------------
--------VTISTDTVRKTTGTTRPSAL----ISE----HVAWETLPEG-----------
---TVVS-------------KQQALYSTEESSLTPGAWALNTT-----------------
------------HV-EVAS-VEGS-ITGSLG----------------------STP----
-----EENGPPAKPSQLPASG------------PKW--SP--------------------
-------GNGSKS--A--YPAQN--PHSLL-----------------Y------------
-VSA----ALKTEMAPRVTLIRMTYF------LEP-TLPDVGK-------NL--------
-PPTQAIL-----TVLE-DPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLVVFPAV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 334)

PQEVSS
VEGNSVSITCYYPP-TSVNRHTRKYWCREGA--SGRCTTLISS---EGYVSDSYAGRANL
TNF-----PENGTFVVKIAQLSRDDSGHYKCGL

ENSGT00530000063436_0_Linker_1_2 (334, 384)

GLN-SRG--LSF---------DVSLEV
SQD--------------PRLLND

PF07686 // ENSGT00530000063436_0_Domain_2 (384, 532)

PEVYTVDVGSTV--TI-------------------NC
PIKSEAAEKKKSFYRMI-GSSHMVVIDST--KYVS------PPYRGRTRLDIH-GTGQLM
FNVVINQLRLSDAGMYFCQTGDD-TGAD----------------KKNVAIQVLA--PEPE
LVYG-----------DLRGSVTFNCALRPE-VANLPKF------------LCRMSNGKNC
DILINTLGKRDPAFEGRILLSPKD-KNGLVSVLITGLRKED-AG---RYLCGAHPDGLLQ
DGWPIQAWQ-LFVNEESTFPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVVCPYNPKE-----SKSIKYWCRWE
GAQ-NGHCPLLVESDRMVKEQ---YKGR---LVLHQEPGNGT--YTVILNQLTSQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 921)

-PGNVTAVVGE--TLKPPCHFPCKFYS--
-YEKYWCKWSEKG--------CRALPSQDEGPSPAFVNCDQNSRIVSLTLNSVTKADEGW
YWCGVKQDHSYGETAAVHVTVKDKKVAGSRNA--S-------------PAKA-----DAA
PDEKVLESGVQ--------E---I-----------------ENKAAQEPRLFAEEKA-VA
DTGDQGGGSRASVD-SSSSEEQG--GSSRVLVSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDGF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMVYRDFLLQSSAVAA-EAQDGP--RE---------A

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWPLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KVEG
ELGGSVTIKCPL-----PEMHVRIYLCREMAG-SGTCGTVVST---TNFIKPEYKGRVTL
KQY-----PHKNLFLVEVTQLTESDSGVYACGAGMNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPAYASSSKFVTRV---------TTPA--QRGKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVAGDKPRTFLPS-----
----TTA-SKISALEGLLKPQMPSYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTILGLFLLALL----GLVVKRAVERRK-A-LS-RRARRLAVRMRALE-
S---TQRPR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------TG-E----APVPGPGA-----P--------------
-----------------------LPPPRC--RCLNLPGSM-P--HL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------ML--------------LTFILLLVVLLLLSFN--------VE

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

SKELVGPKQVSG
FVNGSITIKCFYSTLTKANKYDRKFLCRESGR-LRKCETVIST---SNYVLEKFKNRASL
VDN-----SEKGLIIIKLSGLQPSDQGTYRCGIGNS-ASG--LTA---------VINLAV
TTV--------------PQATLATHVIQLKL-THH-IFIQTLFI----------PPMGIC
FLDINALKTMTYWQGVV-T------------QWIV---------------TFH--QRKSG
LNVFLFKACLGKIPELTL------LNLRRIFYY-------DSLNKVNADTTIQNE---

PF07686 // ENSGT00530000063436_0_Domain_3 (539, 674)

AE
LMYG-----------QLRSSVTFLCKSGKQ-YS-SPKY------------FCKIN-KGEC
RNIINSAGSISSEYHGRIVLSSGE-DQESFIVKLIQLRKED-SG---LYLCGVGSNVEDE
D---SNVFE-LHI

ENSGT00530000063436_0_Linker_3_4 (674, 676)

NE

PF07686 // ENSGT00530000063436_0_Domain_4 (676, 798)

DTDIPQGSRMLIGNIGGSISALCPYNPKK-----NYTVKVWCKWD
KQG----CHPLIRNNGFVQEK---YEGR---ILIHDNPQNGT--MQVLMNQLSAEDKGWY
WCMMTDGTTDQISFVQV

ENSGT00530000063436_0_Linker_4_5 (798, 821)

NIEEGNHEQLAG---QIEVVASA

PF00047 // ENSGT00530000063436_0_Domain_5 (821, 905)

GK--QITIPCTYPCRYTS--
-YQKYWCKWSNYG--------CNPKTSQDNDQDGLNINCEN--QEVVLTINAVEKTDEGW
YWCGVKKFGRYGETLAVHLKVES-EIQKDGDNIRM-------------TLDYGCPDSKI-
----K-QKGCKMRERKAM----------------GDNRIRSDRNVVAESNYIYA------
--------NSSFVTTSGSSSEEG--KSSNI-LAISLSVC--AV-VLLISAVFIVIRLKNR
R--NSELVSV----GSFRTNISMTDLD-NTPNTG-KDNPCINEA-EAQETDMG-------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------LLSSVPTAV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 355)

PQDVSG
VVGNSVSVTCYYPA-TSVNRHSRKYWCRQGP--GSLCTTLVSS---NGYISKEYAGRANI
INF-----PENNTFTINIAQLTQNDTGSYKCGLGTS-NRG--LYF---------

ENSGT00530000063436_0_Linker_1_2 (355, 388)

EVSMEV
SQA--------------PEFPVDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TKDLGRSV--TI-------------------AC
PFKKENAHSKKSLCKKI-GQTCELVIDST--EYVN------PKYKDRAILFMK-GTSQEL
FNVNITHLRHSDAGLYVCQAGEG-SSAD----------------RNNADLQVLD--PKPE
LVYR-----------DLRASVAFDCDLGRE-VADVAKY------------LCRMN-KETC
DVVINTLGRRDPAFEGRILLTHKD-DNGRFSVLITGLKKED-AG---QYLCGAHSSGLPQ
EGWPMQAWQ-LFVNEESTMPPSRS

PF07686 // ENSGT00530000063436_0_Domain_4 (685, 798)

VVKGITGGSVAIVCPYNPKE-----SSSLKYWCRWE
ADG-NGHCPVLVESQGVVDEQ---YEGR---LALFDQPGNGS--YTVILNQLTTQDAGSY
WCLTNGDSRWRSTVELQ

ENSGT00530000063436_0_Linker_4_5 (798, 813)

VAEGERKPNLEV--T

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 914)

PQNAIAVLGE--TLTLSCHYPCKYYS--
-HEKYWCKWSNKG--------CHILPSHNEAARQSSVSCDQDNQVISMTLNPVSKNDEGW
YWCGVRKGQDYGETTAIYVAVEER-TGGSRQV--S-------------PVDANAPA-NVA
PQEEVVDSGVS--------D---N-----------------ENKAIPNPSLLEEEGE-IN
SVGDQAQENRAAVD-AGSADEQK--GHSKILFSTLVPLG--LV-LAGGAVAVWVARVRHR
--KNVDRMSI----SSYRTDISMADFK-NSRDLGGNDNMGASPD--LQETALERKDEI--
-VTTTEIA--------TEPEESKKAKR---------------------------------
-SSKEEA-DLAYSAFLLQSSNIAA-QVHDGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPWLWLLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTITCPL-----PETRVRIYLCREMAE-SRACATVIST---NNFIKNEYKGRVTL
TQH-----PHRNLFLVKVTELTESDSGVYACGAGINTDGG--KTQ---------KVTLNV
HSE----------YEPLWKEQP-----APET--------PNWF--------HL-PH---L
FQMPARASSSKAIPRV---------TTPA--QRTKVPPVHHLSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVADKPPTLLPS-----
----TTA-SEISARGVLLKPRTASYNHHTR-LHRQRALDYS--------SQSGRE-GQ--
-----GFHVLIPTVLGLFLLALL----GLMVKRVVQKRK-A-LS-RRARRLAVRMRALE-
S---SQPPR----------------------------GSQQRRS------QNIYSACPRR
ARG----TDAAG------------NG-E----TPVPGSGA-----P--------------
-----------------------LSPALL--QVSESPWLHTP--SLKTSCEY------VS
LYFQPATKMKDSD--SNDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MAF-----------------FLACLLALLPV--------VSMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 333)

PIFGPEQVIG
TQGGSVSINCFYPK-TSVNKHDRKYFCLRNS--RGSCETIVSS---NGYVSERFTGRANL
TDF-----PKNGTFLIQISQLVPEDSGPYKCG

ENSGT00530000063436_0_Linker_1_2 (333, 385)

VGMI-GRG--LSF---------DITLEM
QQG--------------PNLPNNT

PF07686 // ENSGT00530000063436_0_Domain_2 (385, 502)

EVIVTEVGKTV--SI-------------------NC
PFQQQNLQDKKFLCKKD-GKNCELVIDSQ--NQVG------PDYTGRVRFRIS-GTSSKV
FVVIINQFRKRDVGMYICGVGEDSTAGI----------------QRKFDIQLLK--LEPK
LFYA-----------EQRGSVILNCALGST-VASLPKF------------LCRVKADETC
DLVLNSKGFINNATLGRILFTPID-EPGSFNIMLTQVRKED-AG---LYHCGAQKDGQPS
EDALVRALR-LFVSEET

PF07686 // ENSGT00530000063436_0_Domain_4 (678, 787)

TVPQSPLVVKGPSGGSVSVTCHYNPKE-----SVTLKYWCNWK
DNS---HCTKLVDSSGMVEEA---YEGR---VALFDHPENGT--FTVLLNQLTSEDAGYY
WCLSNG

ENSGT00530000063436_0_Linker_4_5 (787, 813)

EHNRKSSVRIDIIED--QPLLIA---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 917)

PRNIIAQLGQ--TLNISCHFPCKFYS--
-YEKYWCRWSNHG--------CETLSTQDGGNSMAFVDCNQNSKIVSLTLSSVRREHEGW
YWCGVKQGQRYGQTTAVYLSVEEATKTAVQPA------------------N-------SV
LNRDASSSGD------------------------------------------------AE
KSDVRGKGIEVAPD-PGSTKEHS--GGSKVVVSTLVPLA--LV-LVVGALALGIVKARRR
--RFSDRISV----GSYTTDISMSELE-NPRKFGANDNMGASSA--QET-TLRGEDEF--
-ITPTENP--------EEIQEPKQVKR---------------------------------
-SSKEEA-DMAYTAFLLQSNYIANEIPLDGS--TDA---------

------------------------------------MDAEA-----TVKSREQKETVRRG
AEA-HYC------------------------------------------RLMAGT-LPQS
HVTS-RRAGWKMSFFLVLCLLQGSSFTLPQKRPHLRWP----------------WEASV-
--PSRTHLQA-----MGTLMPSSP----LCWR-EGSSF--------AATNVLK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
DPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPS-RWICQTIVST---NHYIHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPEDIGCYLCGIGDENN-L--LFF---------SMNLTV
SAGPSS--SLP-TATPAAGE-----LPMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQATAWDTV----------------
-----------------------------------------------------AS-----
----TLGTSMTRASA---------------------------------------------
------------------------------------EGRQTSGA-TRPAAPGTGSRAEG-
S----PKAP-A------PIPES-------PASES-----------RSRMFNTTEGVWG-G
TRS----SV--TNKAR---AS---KDGREMTTTKVDRPREDT--ER--------------
--------VRIALEAAKKALGTISPPAP----VSE----TLAWEILPQCCLE--------
---TSVS-------------KQQSLGPIGKTTPAAGVWTLGTT-----------------
------------NI-EAAS-GEG-SVAGDLD----------------------AAT----
-----GDRGSQATPSQALAVG------------PWK--PP--------------------
-------GKESSV--KSASSEDE--SNSWTL----APVS--TLLVLFMLMALVLLQRKLW
R-RRT---SQEAE---RVTLIQMTRVL-EVNLQPD-QLPHMER-------KMLQ-DDS--
-LPAGTSL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVNS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--RGGCITLISS---EGYVSSKYAGRANL
TNF-----PENGTFVVNIAQLSQDDSGRYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PGLLNDTKV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDLGRTV--TI-------------------NC
PFKTENAQKRKSLYKQI-GLYPVLVIDSN--DYVN------PNYTGRIHLDIQ-GTGQLV
FSVVINQLRLSDAGQYLCQAGDD-SNSN----------------KKNADLQ

ENSGT00530000063436_0_Linker_2_3 (532, 559)

VLK--PEPE
LVYE-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 665)

GSVTFHCALGLE-VANVAKF------------LCRQSSGENC
DVVVNTLGKRAPAFEGRILLNPQD-KDGSFSVVITGLRKED-AG---RYLCGAHSDGELQ
EGSP

ENSGT00530000063436_0_Linker_3_4 (665, 682)

IQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSIKYWCLWE
GAQ-NGRCPLLVESEGRVKEQ---YEGR---LSLLEEPGNGT--FTVILNQLTSRDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWNNTG--------CQALPSQDEGPSKAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAIYVAVEERKAAGSRDV--S-------------LAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKA-VA
DTRDQADGSRASVD-SGSSEEQG--GSSRALVSTLVPLG--LV-LAVGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQSSTVAA-EAQD-----------GPQEA

------------------------------------MDGEA-----TLKLREQKEVARKG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVAN-RRAGWKMPFFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLQT-----MGTLTPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIHCRYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYTHHRYRDRVAL
TDF-----PERGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATSAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRQTPGA-TRLAAPGTGSWAEG-
S----VTVP-A------PIP-------------------ESPASKSRSMSNTTEGVWG-G
TRS----SV--TNRAR---AS---KDRREMTTTKADRPREDT--EG--------------
--------VRITLDAAKNVLGTIRPPAL----VSE----TLAWGILPRA-----------
---TPVS-------------KQQSLGYVGETTLAVGVWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDGGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SNSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------MDGEA-----PCKPRECKLALPSS
------------------------------------------------------------
-SLGVLWPSVALTAQPSLC--PGSSLAPPHSGPHLGRL----------------RAGPP-
--PPGTHLCA-----EEALS---------------SSS--------ALCSTLN

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

SPRLVSG
ELGGAVTIQCHYAP-LSINRHQRKYWCRVGPP-MWTCHTIVST---NHYTHRDYRGRAAL
ADF-----PQSSLFVVRLSQLSMEDGGHYRCGIGDSNN-R--LFS---------SVNLTV
SAGSSS--TIP-TAPAAADA-----FLTASFRTASPA-ADRWTSGS--------------
----------------------------T--QTLEGQRTKWDRV----------------
-----------------------------------------------------VP-----
----TTETRRTTASA---------------------------------------------
------------------------------------KRRQTPGT-VRAVALGTDRGAEG-
S----TEAT-V------PVPQS-------------------PVSKLRGVSTTTEDVWGWG
TGS----MV--TEGTG---VS---EGGKEVTTTEASKPGEQT--ET--------------
--------TETAVDAARKSTETTSPPA-------------QAWETLPEA-----------
---TMVS-------------KQQALVSAEGATPAAGPWTLDTT-----------------
------------RR-ETAS-VEG-STEAELS----------------------SAA----
-----GDQGPQATTSQGPAAR------------PQR--PP--------------------
-------GKESSE--KSAFPEDE--SGSWAL----APVS--AMLAPFLFVALLLWQRRLW
R-RRR---RR-RKGTPRIALIQMTRFL-ELNHQPD-QLPNMER-------EMLQ---RDP
PHPPQASL-----TVLEEDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTHF-----------------QLTFLLAIFPVI--------SMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 355)

PEEVSS
VEGNSVSIRCYYPA-TSVNRHSRKYWCRQGA--GGMCMTLISS---NGYISKDYAGRASL
TNF-----PEDGSFVVNIEQLTHNDTGSYKCGLGIN-NKG--LYF---------

ENSGT00530000063436_0_Linker_1_2 (355, 387)

GVSLEV
SHG--------------PELLNNTHV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTENLGSTV--TI-------------------EC
PFKRENAPNKKSLCKKI-GQSCELVIDSA--ENVS------PSFNGRARLIIQ-GTSQQV
FRVIISHLRLSDAGMYVCQAGET-SNAD----------------QKNVDLQVLE--PEPE
LVYG-----------DLRSSVTFDCALGPE-VAKEPKY------------LCRMN-NGTC
DVVINTLEKRDPAFEGRILLTPKG-DNGHLSVLITGLRKED-AG---LYLCGAHSSGLPQ
EGWPMQAWQ-LFVNEESMIPQ

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 798)

SRSVVKGVVGGSVAMLCPYNPKE-----SNSLKYWCRWE
GSQ-NGHCPLLVESQGLVQEQ---YEGR---LALYEEPGNGT--YTVILNQLTAQDAGFY
WCLTNGDPRWRTTVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVEAPGEPSLKG--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 909)

-PQNVTAVLGQ--TLTLSCQFPCKFYS--
-YEKYWCKWSNRG--------CRLLPSQDESSRQASVSCSQSSRLISMTLTSISKADEGW
YWCGVKQGHVYGDTAAVYVAVEET-AEGSRHI--D-------------PAPA-----NTA
PEEEVVESSIP--------K---T-----------------EDHAVLNPKLFAEERA-VE
GAKDPAPGNRASVD-AGSSDGHG--GSSRVLVYTLVPLG--LV-LALGAVAVWVARVRHR
--KNVDRVSI----RSYRTDISMADFE-NSRDSGGNDNLGASPV--TQETILKGKDER--
-VTTVESP--------TNPEELKKTKR---------------------------------
-SSKEEA-EMAYSAFLLQSSNIAA-QAHDVP--KDV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----TMLF-----------------LLTFLLAVFPVV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVSS
VEGNSVSIKCFYPD-TSVNRHTRKYWCRQGA--NGLCTTLISS---NGYVSKDYAGRANL
INF-----PENGTFVVNIAHLTQDDSGSYKCGLGIN-N

ENSGT00530000063436_0_Linker_1_2 (339, 386)

RG--LFF---------AVSLEV
SQG--------------PEFPDDTH

PF07686 // ENSGT00530000063436_0_Domain_2 (386, 532)

VYTVDTGRTV--TI-------------------NC
SFSPENSPKMKSFCKKT-DQSCELVIDSA--GTVN------PNFKDRARLLIP-GTSKDM
FKVIIDHLKPSDAGMYVCQAGES-SSAD----------------KKNIDLQVLE--PEPE
LIYG-----------DLRGSVTFDCALGLE-LANEAKY------------LCRVS-DKTC
DVVINTLGKKDPAFEGRILLSEDG--NGRFSVLVTGLRKED-AG---HYLCGAHSSGLPQ
EGWPIQAQQ-LFINEETVIPHSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 798)

SVVKGVVGGSVAILCPYNPKE-----SSSLKYWCRWE
GTG-NGRCPLLVESEGLLQEQ---YEGR---LALYKEPGNGT--YTVILNQLTTQDAGFY
WCLTNGDSRWRTTLELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVDVLGEPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 910)

-PQNVTAVLGE--TLKLSCHYPCKFYS--
-YEKFWCKWSNKG--------CSFLPSHEEGPSQASVSCDQSSRLVSLTLNSVSKTDEGW
YWCGVKEGQYYGDTAAVYVAVEEA-TGGSRHI--S-------------PTHA-----NIA
PEEEVIESSVN--------E---N-----------------ENKAILNPRFFAEEKV-VE
GVRDQAHENRASVG-VGSSDGQR--GSSKALVSTLVPLG--LV-LTVGAVAVWVARVRHR
--KNVDRVSI----RSYRTDISMSDFE-NSRDFGGNDNMGASPD--TQETVLEGKDDL--
-TNTGDIT--------TEPEESKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSNIAA-QVQDGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVNS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--RGGCITLISS---EGYVSSKYAGRANL
TNF-----PENGTFVVNIAQLSQDDSGRYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PGLLNDTKV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDLGRTV--TI-------------------NC
PFKTENAQKRKSLYKQI-GLYPVLVIDSN--DYVN------PNYTGRIHLDIQ-GTGQLV
FSVVINQLRLSDAGQYLCQAGDD-SNSN----------------KKNADLQVLK--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRQSSGENC
DVVVNTLGKRAPAFEGRILLNPQD-KDGSFSVVITGLRKED-AG---RYLCGAHLDGELQ
EGSPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSIKYWCLWE
GAQ-NGRCPLLVESEGRVKEQ---YEGR---LSLLEEPGNGT--FTVILNQLTSRDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWNNTG--------CQALPSQDEGPSKAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEERKAAGSRDV--S-------------LAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKA-VA
DTRDQADGSRASVD-SGSSEEQG--GSSRALVSTLVPLG--LV-LAVGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQSSTVAA-EAQD-----------GPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRLY-----------------LFTLLVTVFSGV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 340)

PQEVSS
IEGDSVSITCYYPD-TSVNRHTRKYWCRQGA--SGMCTTLISS---NGYLSKEYSGRANL
INF-----PENNTFVINIEQLTQDDTGSYKCGLGTS-NR

ENSGT00530000063436_0_Linker_1_2 (340, 390)

G--LSF---------DVSLEV
SQV--------------PELPSDTHVYTK

PF07686 // ENSGT00530000063436_0_Domain_2 (390, 532)

DIGRNV--TI-------------------EC
PFKRENAPSKKSLCKKT-NQSCELVIDST--EKVN------PSYIGRAKLFMK-GTDLTV
FYVNISHLTHNDAGLYICQAGEG-PSAD----------------KKNVDLQVLA--PEPE
LLYK-----------DLRSSVTFECDLGRE-VANEAKY------------LCRMN-KETC
DVIINTLGKRDPDFEGRILITPKD-DNGRFSVLITGLRKED-AG---HYQCGAHSSGLPQ
EGWPIQTWQ-LFVNEESTIPNRRS

PF07686 // ENSGT00530000063436_0_Domain_4 (685, 798)

VVKGVTGGSVAIACPYNPKE-----SSSLKYWCRWE
GDG-NGHCPVLVGTQAQVQEE---YEGR---LALFDQPGNGT--YTVILNQLTTEDAGFY
WCLTNGDSRWRTTIELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VAEATREPNLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

TPQNATAVLGE--TFTVSCHYPCKFYS--
-QEKYWCKWSNKG--------CHILPSHDEGARQSSVSCDQSSQLVSMTLNPVSKEDEGW
YWCGVKQGQTYGETTAIYIAVEER-TRGSSHV--N-------------PTDANARA-KVA
LEEEVVDSSIS--------E---K-----------------ENKAIPNPGPFANERE-IQ
NVGDQAQENRASGD-AGSADGQSRSSSSKVLFSTLVPLG--LV-LAVGAIAVWVARVRHR
--KNVDRMSI----SSYRTDISMADFK-NSRDLGGNDNMGASPD--TQQTVIEGKDEI--
-VTTTECT--------AEPEESKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSTIAA-QVHDGP--QEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPWLWLLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIMCPL-----PETPMRIYLCREMAE-SRACATVVST---NNFIKNEYKGRVTL
TQN-----PHKNLFLVKVTELTRNDSGVYACGAGINTDGG--KTQ---------KVTLNV
HSE----------YEPLWKEQL-----APET--------PNWF--------HL-LQ---L
FQMTAHAGSSKSVPRV---------TTPA--QRTKVPPVHHPSPTTQ--IIHR--PQVSR
AS----------------------------------------SIVADKPPTLLPS-----
----TTA-SEISARGVLLKPRTASYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTVLGLFLLALL----VLMVKRAVQRRK-A-LS-RRARRLAVRMRGLE-
S---SQPPR----------------------------GSQQNRS------QNIYSACPRR
APG----ADAAG------------NG-E----TPVPGSRA-----P--------------
-----------------------LSPTLL--QVSESPWLHTP--SLKTSCEY------AS
LYFQPAAKMEDSD--SNDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MSDSVRV--------AGALKILPEVKM

PF07686 // ENSGT00530000063436_0_Domain_1 (239, 359)

EG
VLGGSITIECPLP-----QMHLRLYLCREMAK-TRGCATVVSS---KNFVKEEYKQRVTL
KPC-----PDKNLFLVEVTELTKSDSGVYACGTGMNTDQG--KTQ---------LVTLTV
FS----------EYEPFWEEEP-----MPEP--------PPWLHRFPHM--PV-PP---W
LQMPARDNSFEFVPKV---------TTPA--EGTEAPPEIHSSPTTP--TSQY--LRVSR
AS----------------------------------------SVAAANPPTFLPS-----
----TRA-SETSAPEGLLKPQTASYNYHTR-LHRHRAFHQD--------PLPGLE-SQ--
-----GFHILVPTTLALILAALL----GLLMKRVIQRRK-A-LS-RRVRRAAVRMRALE-
A---SQRPP-T------QRPR----------------ASQPPRS-----Q-NIYSACPRR
ARA----ADAEG------------EG-E----VPLPGLRA-----P--------------
-----------------------APPATP--QVSEALWLHAP--SLKTSCEY------MS
LYFKPAAKAEDMD--ADDYVNIPCLTHLASCPPGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TLKLREQKEVARRG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVAN-RKAGWKMPFFLILCLLQGSSFALPQERPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLRPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIRCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---SHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGSQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAPKSRSMSNTTEGVWG-G
TRS----SV--TNGAR---AS---KDRREMTTTKADRPKEDT--EG--------------
--------VRITLDAAKNVLGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYVGETTPAVGLWTLGTPAAGV------------W
T-LGTPAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQTTLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MKLF-----------------LFICLPTIFPMV--------SMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

PQEVSS
VEGKSVSITCYYPP-TSVNRHTRKYWCRQGA--RGSCITLISS---GGYISNDYAGRANL
TNF-----PENATFVMNIAQLTRNDSGHYKCGLGIN-

ENSGT00530000063436_0_Linker_1_2 (338, 388)

NRG--LSF---------DVSLEV
SQD--------------PGLQNNIQVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TVDLGRTV--TI-------------------NC
HFKHENAQKKKSFCKEA-GKHCKLIIDSK--GYLN------PDYRDRIRLAIH-GTGQLM
FSVILNRLNFSDAGMYACQAGDG-PTSD----------------KMNVDLQVLK--PVPE
LVYG-----------DLRGSVNFDCDLGPE-LAHDAKF------------LCRMSNGKTC
DVIINTLGKRAPTFEGRILLTPKE-ENGRFSVLITGLRKED-AG---RYLCGAHPDGLLK
DGWPVQAWE-LFVNEETVIPH

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 796)

SPSVVKGVAGGSVAVFCPYSPKE-----SSSLKYWCRWE
GAQ-NGRCPRLVESQGLVQEQ---YEGR---IALLEEPGNGT--YTVILNQLTPQDAGFY
WCETNGDIRWRSTVE

ENSGT00530000063436_0_Linker_4_5 (796, 812)

LKLIE--GEPNLRV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 910)

-PENITAMLGE--TFKIPCHFPCKFYS--
-YDKYWCKWSNKG--------CRVLPSQDDGPSQAFVNCDQNSRVISLTLDSVSKADEGW
YWCGVKQGHRYGETAAIYVAVEEK-GKGFHDV--S-------------PANA-----NVL
PEEKLVESGAK--------E---I-----------------ENKVIQDPRLFAEEKA-VE
DVGDQAGGSRASVD-TSSSEGQG--GSSTVLVSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----GSYRTDMSMSDFR-NSREFGANDNMGASPV--TQETSLEGKTEF--
-TATTENT--------TKTEEPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQSRNVAAAEAQNGP--RDA---------

------------------------------------MEGEA-----PTKPRGQ-------
------------------------------------------------------------
-KXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------
---XXXXXXXXXXXXXXXXXXXXX----XXXX-XXXXX--------XX

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ANALKGPKLVSG
EPGGAVTIKCHYAS-TSVNRHQRKYWCRLGPP-KWICRTIVST---NYYTHLSYHGRVAL
EDV-----PWRSMFVVRLSQLSPTDEGYYRCGIGNRND-M--LFF---------SVNLTV
SAGPSS--TIP-TATPAVSE-----LSLRSLATASPA-ANRWTSRT--------------
----------------------------T--QVVEGEKTGWDSV----------------
-----------------------------------------------------VP-----
----TT--------A---------------------------------------------
------------------------------------KEGQPPRI-TKTIAPRTRSWVES-
S----PRAT-V------LSPES-------------------RTSQLTVMLNTTENFWVWD
SRS----SV--ANGAR---MS---KEVRKMTTRQVSGPTEET--RR--------------
--------VRTAPDGTWNVTGTIRPSTP----VSE----KWAWENLQGAT-L--------
-----VS-------------KQSALGFTEETTPAAGVWTLATT-----------------
------------SI-EMAT--EE-GSPEED------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

-------------------------MSPKGSYFWTEVDGEA-----PQQPPKYKVSN---
------------------------------------------------------------
-----RWAEWRM------------------------------------------------
------PFLL-----LLLVL---------------CLL--------QAVKALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
ELGGAVTIQCHYAP-LSVNRHQRKYWCRVGPP-MWTCHTIVST---NRYIRLGYHGRVAL
TDF-----PQSSLFVVRLSQLSMDDEGNYRCGIGDSNN-M--LFF---------SMNLTV
SAGSSN--TIS-TAPLAAGE-----FLTESSGIASPA-AKRWPSGA--------------
----------------------------T--QTPEGQRTKWDKV----------------
-----------------------------------------------------AP-----
----TRETRKTTASA---------------------------------------------
------------------------------------KRRQTPVT-VRAVALATDSGAEG-
S----VKAT-V------PIPQS-------------------PGSKLNGVSTTAEDACGWG
TGS----LV--TKVTR---VR---EGRKEMTTTEANKPGEQT--ER--------------
--------TETAVDAARKTTGTIWPSA-------------QAREALPEA-----------
---TMVS-------------KQPALGSTEGATPAAGPRTLNTT-----------------
------------HR-ETAS-VEG-SPEGDLR----------------------SAA----
-----GGQGPQATPSQGPVAG------------PQR--PS--------------------
-------GKGSSR--KSASPEVE--SGSRIL----TPVS--TLLAPFLLVALVLLQRRIR
R-KRS---SQEAERTPRVTLIQMTRFL-GLTLQSD-QLPHMER-------EILQ-GNPPP
PLPPQAGL-----TVLERDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-----------MPLLLILCLLQGSSLTPPHRRPYLRWL----------------QDGFL-
--PSGTHLWA-----IE--MPSSS----LCWQ-E-SPL--------AAANAL

PF07686 // ENSGT00530000063436_0_Domain_1 (233, 344)

KGPRLVSG
VPGGAVTIQCHYAP-SSVNKHQRKYWCRLGPP-RWICHTIVST---NHYTHPHYHNRVAL
VDF-----PQKGFFVVRMSQLSLDDVGCYHCGIGDGNA-M--LFF---------SMNLTV
SAGPSS--TLP-IATSADGG-----LTTRSFGIAPPA-ANRWTPGP--------------
----------------------------T--QTTEGQGTEQDRV----------------
-----------------------------------------------------AL-----
----TLGAST-TASA---------------------------------------------
------------------------------------KGSQTPGT-TRTA--RTGVWVVG-
P----IKAT-V------PIPES-------------------PASKTRSISNITAGVWIWG
TRS----SI--TNRAV---VS---NDRRQITTTMADRPGEET--EG--------------
--------VKIALDAATKVIGTMRPSAL----VSE----KLSWETLQEA-----------
---TPVS-------------EQRFLSSIEGTIPGTGMWTLATT-----------------
------------SI-ETAS-MEG-STEADGD----------------------GAT----
-----EDSGP-------PIAG------------YPR--PP--------------------
-------GKESSR--KSAFPEK---NSSRIL----TPVS--TILVPLVLVALVLLQRKLS
R-RRT---SQEAERAPRVTLIQMTHFL-EPSHQAD-QLPHVER-------KMIQ-EDP--
-PIAQASP-----TIPERDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTFF-----------------LLACLLAAFPVV--------SMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 336)

PIFGPQEVSS
VEGNSVAITCYYPP-TSVNRHTRKYWCRQGA--SGRCTTLISS---EGYVSNDYADRASL
TNF-----PENGTFVVNVANLTQNDSGRYKCGLGI

ENSGT00530000063436_0_Linker_1_2 (336, 385)

S-SRG--LSF---------DVSLEV
SHG--------------PNPLSNT

PF07686 // ENSGT00530000063436_0_Domain_2 (385, 527)

QVYTVDMGRTV--TI-------------------NC
PFKRENAQKIKSLCKKT-GSSCLLLIDSN--KYTH------PNYLGRISLIIQ-GTSQST
FSVILKEVRLRDAGMYICQTGND-PSGD----------------KK

ENSGT00530000063436_0_Linker_2_3 (527, 557)

NVDLQVLK--PEPE
LVYG-----------D

PF07686 // ENSGT00530000063436_0_Domain_3 (557, 662)

LRGSVSFDCAPGPE-VKDVAKF------------LCRVTKEEKC
AMVINTLGERDSAFEGRILLTQKG-KNGEFSVLITGLRKED-AG---HYLCGAHSDGLMQ
E

ENSGT00530000063436_0_Linker_3_4 (662, 682)

GNPAQAWQ-LFVNEETRMPH

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 797)

SPSVVKGVAGSSVSVLCPYNPTE-----DSTSKYWCRWK
GEG-SGRCPLLVESQGLVQEQ---YEGR---LALLDEPGNGT--YTVILNQLTPQDAGFY
WCLTNGDTRWRTTVEL

ENSGT00530000063436_0_Linker_4_5 (797, 813)

KVIE--GKPNLKV---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 915)

PETVTAVLGK--PLKLPCHFPCKFYS--
-HEKYWCKWSNKG--------CQVLPSQDEGPSDAFVNCDQNSQIVSLNLNSVTKKDEGW
YWCGVKQGHSYGETAAVYVAVEEK-VQGSSDV--S-------------RANT-----NAA
PGE-LGEPRAR--------E---V-----------------ENKAVQDPRLFAEEKA-VK
EAGVAAGGSGAPAD-ASSSKGQS--GTSKVVLYTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSV----ASYRTDIGMSDFE-NSREFGANDNMGASPV--TQETSLEGKDEF--
-NTTTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYTAFLLQASNVAA-EAQDGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------TLI-S---DSYI-SEYQGRAKL
THF-----PKNNTFVVDIAHLTKNDSGHYKCGLGIN-NRG--LSF---------DINLQV
NQD--------------PILPDGTKIYKTYMGGTV--AV-------------------DC
TFKAENSEKLKSVCKKS-NQGCVLVINSS--GYIN------PNYENRAHFFIY-DTSAAK
YKFIIKNFSSXXXXXXXXXXXXXXXXXX----------------XXXXXXXXXX--XXXX
XXXX-----------XXXXXXXXXXXXXXX-XX-XXXX------------XXXXX-XXXX
XXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX-XX---XXXXXXXXXXXXX
XXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXX
XXX-XXXXXXXXXXXXXXXXX--XXXXX---XXXXXXXXXXX--XXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

EIDLKV---PKNVIALEGE--NIKIPCHVPCKFYS--
-YDKYWCKWTNKG--------CRTFPSQDEGPSQAFTECRQKSQLINLVLNSVTKKDEGW
YWCGVKNSLRYGDSVAVYVTVNKV----SQDV--S-------------Q------V-NAD
PQEEAIEPGVR------TIE----------------------NKAIQNPSLLAEGRA-VE
ETRNSADDSRASTD-PESSVGQG--RNSSVVVYILVPLA--LV-LTLGAVALGVARARHR
--RNVDRISI----RSYRTDISMSDLE-NSKDLGAIDNMGASPI--KQETSLGGKDES--
-MSTTRNT--------METDEPKKVKR---------------------------------
-SSKEEA-DMAYTAFLIQSNNMAA-NTHDSP--SEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MCLWLWLLYFLPV--------SRTLKVLPEVK

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 361)

LDV
EWGGSITITCPLP-----QTPVRMYLCREMAD-HGICATVVSS----SFVKKEYERRVTL
TPC-----LDEKLFLVEMTHLTESDSGVYACGVGHYTDRG--KTQ---------KITLNV
HSEY----------EPFWEDEP-----TPEP--------PPWFHRFPWE--QI-PS---W
LIEDEHASPE-FIVEV---------TTPA--PKTEASPADQPSSTNP--VTHH--PRVSR
TS----------------------------------------SVTAAKSPALLPA-----
----TTP-PKTSAQQA-LGSLGASYSHHTR-FHRQRTLHHS--------PQHGRE-DRAL
HIPILEFHILIPTFLAFLLLVLL----GLMVKRAIQRRK-A-FS-RRMGRVAMRIRGQG-
A---SRPFP-A------QRRG----------------APQRPRS-----QNNVYSACPRR
API----PDRVG------------PA-E----APLLSAPG-----S--------------
-----------------------ASPAPPQVQVLEAPWPHTP--PLKTSCEY------VT
LCHQPAVNVGDTD--SDDYINIPGPHHLPSCLPGPRPSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLCFLPV--------AGALRNLPEVK

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 361)

LEG
ILGSSITIECPLP-----QKHVRLYLCREVAE-SGVCSTVVSS---KNFVKEEYKHRVTL
KPY-----PDQNVFLVEVTELTKSDSGVYACGTGMNTDRG--KTQ---------QVTLSV
HS----------EYDPFWEDEL-----MPEP--------PRWFHKFLHR--PM-PP---W
FKMPAHADSLEFIPKA---------TPPA--QRTEAPPATHPSPTTR--ISHH--LQVSR
AS----------------------------------------SVAVTKPPTFLPS-----
----TTTTSKTSTPGVLRRLQTASYNYHSR-LHRQRAFHQG--------PVSGME-DQ--
-----GFHILVPTALSLILLALV----GLLVKRAIQRRK-G-V-----------------
------------------------------------------------------------
-------------------------P-E----APLAGLGA-----S--------------
-----------------------ASPAAP--QVMETVWLHAP--SLKTSCEY------VS
LYYKPVAKAEDTD--SDDYVNIPCLTHLSHCPPGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDREA-----SAKPGEG-------
---------------------------------------------------------QYF
LQVTKQRAGWKLPIFLTLCLLQGSALTPPQRRPHLRCL----------------RTVSL-
--PSAPRLWA-----KETLTPFSP----LCRR-GKTSI--------ADANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
EPGGTVTIQCHYAP-LAINVYERKYWCRLSPL-TSFCHTIVST---TGYAHLGYRGRVTF
ADF-----PQRGLFVVRLSQLSPDDVGRYRCGIGKRND-M--FFF---------SMNLTV
SAGLSS--AVS-PPTLAAGE-----LVVASLGTATPA-ANRWTPAT--------------
----------------------------S--RMTERQGTGFHRV----------------
-----------------------------------------------------AL-----
----TPGTRKTTASA---------------------------------------------
------------------------------------EGRQTPGA-TGAAALGTGSRVES-
S----VRTT-V------PIPES-------------------SASPIGDMSNTTEGVWVWD
TNG----SV--GDSGR---PS---EEGREITPTEADRPQEEA--ER--------------
--------VRTALDAVGKVTGTIRPTTL----VSE----KRVQEILQEA-----------
---TAIA-------------KPQALGSIERTTPAAGVWTLGPS-----------------
------------SI-QVAS-EEG-ATEGDLD----------------------TPA----
-----GYSDPQATLNQAPAAG------------PRR--PL--------------------
-------GKGYSM--KRASPGEK--NISRIL----TPVS--TVLFPLTLVALVLLQRRLR
I-NRT---SQETEGTAGVTLIQMTHFL-ELSLQPD-QLPHVER-------KIFR-DES--
-PP-QARL-----TVPERHPGPQGVEQ---------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLS-----------------LLIFLLAIFPVV--------STESPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

PKEVSA
VEGSSVSIMCYYPS-TSVNRHTRKYWCRQGA--KGSCMTLISS---GGYISEDYLGRSNL
TNF-----PALGAFMVNIAHLSREDSGHYKCGLGNS-NRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 390)

NF---------DVSLEV
SKD--------------PRLLNNTDVYTM

PF07686 // ENSGT00530000063436_0_Domain_2 (390, 533)

DMGRTV--TI-------------------KC
PFSDKNAAKKKSLCKKT-DQSCELVINSN--GDIS------PSFQGRVRLVIQ-GTSQDT
FTVIINQLRTDDAGMYVCQAGED-PSSD----------------QRNVDLQVLE--PEPE
LVYG-----------QLRGSVTFDCALGPE-VAKLPKF------------LCRVNKNKPC
DVIINTLGKRDPAFEGRILLSPKDPDNGRFSVLLTGLQTED-AG---EYLCGAHSDGEPQ
QGWPLQAWQ-LFVNPETIIPRTR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 790)

TVVKGVTGGSVAVLCPYDPKD-----SNSFKYWCRWE
GEQ-SGRCPLLVESQGKVQEE---YEGR---LALYEEPGDGF--YTVILNQLTTQDAGFY
WCLTNDDTR

ENSGT00530000063436_0_Linker_4_5 (790, 812)

WRTMVEIKVAD--GEPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 912)

-PKNKTAVLGE--PLKLHCHFPCKYYS--
-YEKFWCKWSNQG--------CQALPSQDEGPSQASVSCQS-TQLISMTLQSVTKEDEGW
YWCGMKQDRSFGETAAVYVAVEEK-AKGSDA------------------VNP-PTA-NSA
PEEEVVQPRGR------EVE----------------------NNAVLNPRLFAEERV-VE
DTGNQASGSRASVD-TSSSEGQS--GSSKVLLSTLVPLG--LV-LALGTVAVWVARARHR
--KNVDRLSI----RSYRTDISMSDFE-NSRDYGGNDNMGASPV--TQETVLEGKVEV--
-MANTEST--------MDAEEPRKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSNIAA-QAQDGP--KDA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MNFWPWLLIFFPV--------SG

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ALKIIPELKLEG
ELGGSVVIECPLP-----EMYARVYLCREVPG-SAVCATVVSN---KNFFRKEYKRRVTL
ELF-----PERHLFLVEVTELTKSDSGVYACGVGMHTDEG--KIQ---------LVTLKV
YSXXXX--XXXXXXXXXXXXXX--------X---------XXX-X-XXX--XX--X----
XXX--XXXX---XXXX---------XXXX--XXX--XXXXXXXXXXXXXXXXX--XXXXX
-X----------------------------------------XXXXXXXXXXXXX-----
----XXX-XXXXXXXXXXXXXXXXXNHHTR-LHRQRAFNYA--------SLPGRE-NL--
-----GFHILIPTTLGLILLVLL----GLVVKRAIQRRKXX-XX-XXXXXXXXXXXXXX-
X---XXXXX-X---------X------------------------------XXXXXXXXX
XXX----XXXXXXXX----XX---XA-E---ETSLSAPGA-----S--------------
-----------------------AIPAPL--QLPEAPWLHAP--SVKTSCEY------VS
LYHQPAAKMEGTD---SDYINMPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWPLYFLPI--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KVEG
ELGGSVTIKCPL-----PEMHMRIYLCR-MAG-SGTCGTVVST---TNFIKAEYKGRVTL
KQR-----PHKNLFLVEVTQLTESDSGVYACGAGMNTDRG--KTK---------KVTLNV
HSE----------YEPSWEEQP-----MAKT--------PKWF--------HL-PY---L
FQMPAYTSSSKFVTRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVAGDKPPTFLPS-----
----STA-SKISALEGLLKPQTPSYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILVPTILGLFLLALL----GLVVKRAVERRK-A-LS-RRARRLAVRMRALE-
S---SQRPR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------KG-E----APVPGSGA-----P--------------
-----------------------LPPAPL--QVSESPWLHAP--SLKTSCEY------VS
LYHQPATKMEDSD--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFISMLLFLLQV--------SNAA--RRRV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 356)

QMTG
EVGKSITIICPVE-----DMSERKFWCREI---TKACVTMIST---SPYIDETYKDRISI
SER-----PQERLFQVTIRRLEEEDAGLYACGTGYHNDRDSGKTL---------QVELNV
FNG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDQDA-------------------
---------------------------------------------------PAKPS---E
QKVPSLRTRWEI-LLLILCLLHGSSMTPPRRRSHSRWL----------------QAGSP-
--QFRTHLYT-----VEAHTAPTP----LCCW-K-NSL--------SGTNALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 360)

PRLVTG
NTGGAVTIHCHYAP-SSVNRHQRKYWCRLGSP-LWICHTVVST---NQYTHPDYRGRAAL
TDV-----PQSGLFVVRLLQLSLGDVGLYRCGIGNRND-M--LFF---------SVNLTV
SAGPSN--TTYAA-APASSE-----PTTASPGAASSA-GNGWTSGI--------------
----------------------------T--QILEGSGSEWDRT----------------
-----------------------------------------------------AP-----
----TTGTSKTTSSA---------------------------------------------
------------------------------------NGRQTLRT-VRTMVPGTGSREEG-
S----IKAA-V------PTPEG-------------------PSPKSRSMSSTTQGVWLWS
TRN----SV--ATSVT---TS---EGRRQGTTPETDGPRDET--D---------------
--------VSMSPEAPRKTTGTTRPSAL----ISE----HVTWETLQDK-----------
---TEVS-------------KQQMLHSLEELSPAPSAQTLNAT-----------------
------------CL-EVAS-EEGRSIDGSLE----------------------NTT----
-----EES-SPPTPSQPSVAG------------PVW--VS--------------------
-------GKGTSM--KSALTEGE--SHTRIL----TPVS--TVLALLLIAALILLKRSLG
RQRT----SQKKGRVPRITLIQMTHF------VPD-KLPDEGK-------NFQQ-SDL--
-LPPQASL-----TVLENDPRA--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLISS---EGYVSSNYAGRANL
TNF-----PENGTFVVNVAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTVDVGRTV--TI-------------------KC
PFKTENDPKVKALYKKI-GETSVLVIDSR--NYVN------PNYNGRIGLHIP-GTGQLI
FTVVIDRLRLSDHGLYLCQAGDG-SSRD----------------EKNVDLQVLK--PEPE
LVYA-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVSSRETC
DVVINTLGKRDSAFEGRILLNPQD-QDGSFSVVITGLRKED-EG---RYLCGAHSDGRLQ
EGWPIQAWQ-LFVNEESTIPHSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 791)

TVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCLWE
GTK-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTHW

ENSGT00530000063436_0_Linker_4_5 (791, 812)

RTTVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------Q---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSRALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGACSI--TQETSLGGKDEF--
-VASPEST--------TENQEPKKAKR---------------------------------
-SSKEEAE-MAYKDFLLQS----------ST--MATKAQEGHQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------TSALT

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 344)

GPWLVTG
KLGGKVSIECHYSI-NSVNRHQRKYWCRLQVP-KRICHTIIST---NRFVRKDYQGRVSI
QDF-----PGNGSFVVALAQLTPHDTGHYRCGIGARTD-M--LFI---------NMDLII
SAGRWASSQGKRKSEAAAEE--------FSPVTESPL-GNSWTPGG--------------
----------------------------L--HSLKNGQPAHRRTRGTITASTP--PADRR
TK----------------------------------------RTTTATTPLTVKR-----
----TPGTVVATTPL---------------------------------------------
------------------------------------TRRQTPGS-TDVTTPPADRRTKR-
T----TTAT-T------PLT-----------------VRRTPGSTVAT------------
---------------T---PL---TDRRTLGTITASTPPADR--RT--------------
--------RRTTTATA-PL---------------------TVRQTPGTVVAT--------
---TPLT-------------RRQTPGSTDATTPLTDRRTKRTTT----------------
------------AL-ELSEKTVE-SVSGEWS----------------------RPP----
-----PD--PQIPLERC----------------PLS------------------------
---------VIPA--SPALPYLH--ERARHFPLKLIPTT--LVLLPLAIIGLVLLKRRLQ
R-KSRESVSQSTLRAERVTLLNLAHF----------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MAL-----------------LFFCLFALLPGAYSEQGSVSPASSPI

PF07686 // ENSGT00530000063436_0_Domain_1 (233, 339)

IGPSKVSG
IPGGTASIKCFYPP-TSVNKHDRKYWCKLGP--RGQCITLISS---GGFVTKELAGRATL
TNF-----PEQNMMEVDITQLGEKDSGDYRCGVGAN-N

ENSGT00530000063436_0_Linker_1_2 (339, 382)

RG--LYF---------NINLNV
RKG--------------PLPS

PF07686 // ENSGT00530000063436_0_Domain_2 (382, 503)

EDPQVYVAEQDGTV--NF-------------------TC
PFQVP--NNRKYMCKQE-DTSCTDVIDSI--GYVN------PEFQGRVSLTVH-DTMRKN
FTISLSRIRQEDTGNYVCGTGI

ENSGT00530000063436_0_Linker_2_3 (503, 555)

YGGQGD----------------RSNLVLELLE--PESE
LVYS----------

PF07686 // ENSGT00530000063436_0_Domain_3 (555, 655)

-ELGGSVTLKCALGQQ-QAAVPKY------------LCKKE-GENC
LTVVNTKGNRDKAFEGRVLLANQE-PPGSFSVSITRLRKTD-AG---LYLCGAN

ENSGT00530000063436_0_Linker_3_4 (655, 681)

RDGAYG
GEGPFQAKE-LHVSEEVTLP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 789)

QGPQVVKGVVGGSVAVQCPYDPKE-----NKTLKYWCQWK
GNS---HCPNLVDSAGMVKED---YKGR---IALFDQPDKGI--FTVVLNRLTPEDVGHY
WCLTSGER

ENSGT00530000063436_0_Linker_4_5 (789, 813)

ERKSTVLLNVTQG--EPSLKA---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 916)

PQEITGQLKR--SLNISCHFPCKYSS--
-YEKFWCKWSRQG--------CQPIPSQDQGPSDAFVDCNQKSRIVSLSLNSLKETDEGW
YWCGVKKDGNYGETTSIYLRVEKPADVR--PE------------------N-------KA
SGVGQEKSGAD--PSRSATGSSCPLDSPTPVWVTGTS----ARVSCPSPRCVHTSLY-PP
THEEKGSSASLSPL-V-VSSVSG--QGSHVLVSTLVPVA--FV-LVIGTIALLVIRARLR
--KNSDRVSV----GSYRTDISMSDFE-NSHDFGVKDNVAASPT--ALETQLGEEAEF--
-IPSKENP--------EVVEEPKVAKR---------------------------------
-SSKEEA-DMAYTAFLLQANHIASGIPLDNP--PEV---------

MPVGAVSRFKEEQLEDVQTPASHKKKSPPGSCFSTEMDGEA-----TLKLREQ-------
------------------------------------------------------------
KVAN-RRAGWKMPFFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLTPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIHCRYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYTHHRYRDRVAL
TDF-----PERGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATSAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGRQTPGA-TRLAAPGTGSWAEG-
S----VTVP-A------PIP-------------------ESPASKSRSMSNTTEGVWG-G
TRS----SV--TNRAR---AS---KDRREMTTTKADRPREDT--EG--------------
--------VRITLDAAKNVLGTIRPPAL----VSE----TLAWGILPRA-----------
---TPVS-------------KQQSLGYVGETTLAVGVWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSALPEDE--SNSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------MDGDA-----HQKPR---------
-----------------------------------------------------------E
RKVANQKAGWKVLLLLILCLLQGSSLSPAHGGPHLRWL----------------LDGSL-
--PSR--------------TPSSP----LCWR-E-SSL--------AVANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
KPGGAVTIQCHYAP-SSVNRRQRKYWCRLGPP-RWTCRTIVSS---SRYTHYRYHGRVAL
ADF-----PQRGFFVVRLSQLSLDDVGCYHCGIGDGST-M--LFF---------SMNLTV
SAGPSS--SLP-TATPAAGD-----LPPRPSETASPA-ADRWTPGL--------------
----------------------------T--QTTEGRGTGWDRG----------------
-----------------------------------------------------AP-----
----TPGASTATASA---------------------------------------------
------------------------------------KGRQTPGT-TGTAAPGTGVWVEA-
S----VTAT-V------PVPES-------------------PASNTSSLSNTTDGVWMWR
TRS----SM--TNRAI---VS---KDRREMTTTQADRPRVET--ER--------------
--------ARISVDVARKVIGTSRPPAL----VSE----KLPWEIPQET-----------
---TPVS-------------KQPFLGWTEGTTPAAGVWTLGAT-----------------
------------SI-ETAS-VEG-STEGDLD----------------------AAA----
-----GDSGPQATPSQAPAAG------------PLR--PP--------------------
-------GKESSV--KSALPEK---SSPRIL----TPVS--TMLAPFMLAALVLLQRKLR
S-RRT---SQEAGRAPRVTLIQMTPFL-EPSLQAD-QLPPVER-------KMLQ-DGS--
-PAAQASL-----TVPERDLGPREMER---------------------------------
---------------------------------------------

------------------------------------MDGEA-----TLKLREQKEVARRG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVAN-RKAGWKMPFFLILCLLQGSSFALPQERPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLRPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIHCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---SHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGSQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAAKSRSMSNTTEGVLG-G
TRS----SV--TNGAR---AS---KDRREMTTTKADRPKEDT--EG--------------
--------VRITLDAAKNVLGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYVGETTPAVGLWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRRPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRT---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHVRMYLCREMVE-SGTCGTVVST---TNFIKMEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YGPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHH--PGVSR
AS----------------------------------------SVVGDEPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
AR----------------------------------------------------------
--------------------------------VSESPWFHAP--SLKSSC--EY----VS
LYHQPAAKMEDSN--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDILFWIIFFLPI--------SKALKSLEKIN

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LSG
YLGGSIVIRCPLK-----NLRQRTYLCREAI--SKSCQTVVSN---KGFVEKNFEDRVSL
KLL-----PEENVFLVELRKLKEGDQGNYACGVGDKTDRG--KTQ---------KVTLKV
TKD----------YYPFWEYPEFTEY--------------------------LPPP---W
EWIPNEASSSLSTTQAS-STSAPKSHPWQ--VQTQPPPPIHPSPTSPVLLL--------R
NT----------------------------------------LAAAAPSQTFSSS-----
------EASKTPRLGRLLRAPTDSYPHHTR-LQSESASYFG---------SSLKK-DG--
-----GFHILILATLGMFLMMLL----GLVLGRTLQKRR-A-LS-KRINRLTLRMSALE-
A---SSRAY-SHLYHSHQRSL-------------HRPVSNRPRS-----QQNIYSACPRQ
VQG----PNQNGENI----SG--------------REPGV-----L--------------
-----------------------EHSTTT--QVSKMAQLQAP---VPVNNEY------GS
TYYLGLAEPEEDD--SHDYINVSCLTQLPCSPPVLGFHANQDCC----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDLES-----PAKPGDP-------
------------------------------------------------------------
-KVTSQRAGWRMLIFLLMCLL--PAVVPAHRRPHLRWL----------------QAGSL-
--PAGPHPWA-----LSHPVAGDS----F----L-PLP--------AAAS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 343)

ALTGPRLVSG
ESGGAVTIRCRYPR-SAINSHQRKYWCRLRPS-TGVCRTIVST---NHYTHLRYRGRVAL
ADFPKRDFPKRGLFVVRLSQLTPEDEGRYRCGLGSSNN-A--LFL---------SMNLTV
SPGLSR--TIP-TATLAYGE-----LITGSFEIASPPAAKRCTRGN--------------
----------------------------T--QTTGRQRTGWDTA----------------
-----------------------------------------------------AL-----
----TPGSRKTMASA---------------------------------------------
------------------------------------TGGQTPGA-AAVLAPGTGSQAEG-
S----VWAT-V------PTVQS-------------------PASTIRGMTGATERGLVWS
TSN----SE--ATRAT---AS---ERERET-TPGTDRPSEET--ES--------------
--------ISTTPGTPETAAGSVRPSTL----ASE----RWMWEPLQEE-----------
---TSAS-------------EPQSLGSVEGTIPAAAVWTSEPT-----------------
------------RI-EMAS-AEG-SGDGDLG----------------------TPA----
-----RDGGSHVMPSQALAGG------------APX------------------------
---------ESSV--KSASLEEK--NFCGIL----TPVS--SALCPLMLVTLVLWKRKLQ
R-KKS---SQKTGRSSGVTLIQMTQSP-ELGLQPG-QPPQVGR-------KRLQ-VDP--
-PPLHTSL-----SLPARDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------MGQALWRGRAAHSPHQRVRVRILPPPLIQIPTNAHWEAAVDGSST
WVQCHPAPLG-----WD--PAREGAMDFRLWLLCFLPV--------AGALKPLPEVQLEA
EL

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GGSVTIKCPL-----PEVEGRMYLCRQMAE-SRACATVVS----NHYTKDEYKSRVTL
TQR-----SEKHQFLVKMTELTERDSGIYACGVGINTDRG--KTK---------KVALNV
HSE----------YEPFWEEEP-----TTKP--------PKWLYRLPHL--QM-PH---G
FRMPVPGSSFRLTPKV---------TTPA--QSTEAPAAHRPSPTTA--PARQ--PRVSR
AF----------------------------------------SGAAARPPTLPPS-----
----A---SKFSAQGGPLRPWTASYSRHTR-LHRQRALSHE--------PPSGTG-DQ--
-----GLHILIPSGLAFLLLALL----GLVVRRALERRK-A-FS-RRFRSLNVKMRHAT-
R---TRRPH-A------QASP----------------HLAADRA----------LRTSTR
ARN----ATRSG------------AG-R---CG---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLS-----------------LLVSLLAIFPVV--------STRSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

PKVVSA
MEGSSVSITCYYPD-TSVNRHTRKYWCRQGA--TGSCVTLISS---EGYISKGYVGRSDL
TNF-----PASSYFVVNITHVNREDSGHYKCGLGIN-

ENSGT00530000063436_0_Linker_1_2 (338, 387)

TRG--LNF---------DVGLEV
SED--------------PRLLNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTGDVGGTV--TI-------------------SC
PFSSENAQKKKLLCKEK-DETCELIIDSN--NAVN------SDFDGRVRMVFP-DTVQRL
FSVVISQLRPSDTGVYVCQAGED-PSGD----------------KTYVDLQVLK--PQPV
LVYG-----------QLRGSVTFDCALGPE-MANVHKF------------LCRVNKDKSC
EVIINTLGKRDPAFEGRILLLPGDASDGRFSVLITGLRTGD-EG---QYLCGAHPDGVPT
DGWHLQAWQ-LFINQETIIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QTPTVVKGVTGGSVAVRCPYNPKE-----SESLKYWCRWE
GEG-NARCLLLVESQGLVQAE---YEGR---LALFEEPGNGS--YTIILNQLTAKDAGFY
WCLTNGDIRWRTTVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVDG--EPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 921)

-PENTTAVLGE--TVKLDCHYPCRFKA--
-DIKYWCKWSDQG--------CPALPSQDESPGQAHTSCDPDSGLISLSLQSVTREDEGW
YWCGVKEGETFGETAAVYLAVKEA-ARGSGVP--N-------------PANP-QIA-NSA
PEEEVVVPQGR------EVENKAI-----------------QNKAVLNPKLFSEERV-VE
DPGNQAGGSRASSS-DSSSQGQS--RTSKVLLSTLVPLG--LV-LLIGTVAVWVARARHR
--KNVDRLSI----RSYRTDISMSDFE-NSRDLGGSDNVGASTV--TQETELEGKVEA--
-MANAEST--------VDTEEPKRAKR---------------------------------
-SSKEEA-DMAYSAFLIQSSNIAA-QAQDGP--TDA---------

------------------------------------MGGEA-----PTKPRGQKVRVVKR
APG-CPS------------------------------------------QSWLGS-LPG-
GQVTSQRVGWTIPLLLTLCLLQGESQTRPSFKAFQKWE--------------STWHGSL-
--R-----WS-----LELDPPQTQTTLSTRSP-FSSLP--------AAATAL

PF07686 // ENSGT00530000063436_0_Domain_1 (233, 344)

KGPRLVSG
EPGGDVTIKCRYNP-TSINRHQRKYWCRLGPP-MWSCHTVVST---NHYTNLRYRGRVAL
EDF-----PQCGFFVVRLSQLLPEDVGHYRCGIGNRND-M--FFF---------SMNLTV
STGSSS--IIP-SATVAAEE-----LAMRSFGTASPV-VNRWIPGA--------------
----------------------------T--QTIEGQGTGCNRA----------------
-----------------------------------------------------AL-----
----TPRPSRMIAPT---------------------------------------------
------------------------------------KRGQTSET-TEAIGPAMGSWVEG-
S----FRAT-V------STPES-------------------QTVKTGGLSKTSEGIWVWA
TKT----SV--GNRAR---ES---EGSREISTTKADRRREET--RR--------------
--------VRIGLDGNWKVIGTIRHQLW----CQK----SGPGKPSKRA-----------
---MPVS-------------RRQALGPIKA-TPAPGMWTLGIT-----------------
------------ST-ETAS-TEG-SPDGDQA----------------------GAA----
-----GDGGPQATSSQALAAG------------PQR--PL--------------------
-------AKGSSM--ESSSPEES--SLAGIL----TPVS--TVLVSFVLVPLVLLQRKLR
S-RRT---CEAGE---RSVLTQMTHLL-ELSLRPD-QPPHMER-------KMVR-GDS--
-PT-HASL-----AVPARDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMFF-----------------FLTCLLAVFPVV--------SMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 338)

PIFGPPEIDS
VEGTSTSIKCYYPP-TSVNRHSRKYWCRQGP--KGQCTTLISS---NGYVSKDYEGRANL
TNF-----PESGTFVVNIDHLVQGDSGSYKCGVGIN-

ENSGT00530000063436_0_Linker_1_2 (338, 391)

NRG--LSF---------DVRLRV
VPG--------------SGVLNGTQVYAED

PF07686 // ENSGT00530000063436_0_Domain_2 (391, 526)

LGGKV--SI-------------------SC
PFTSANLPNVKSVCKQIADKHCIRVIDSA--GYKG------PNYEGRAKLIIQ-GTTQTE
FFFVIDQLQVEDDGKYVCQAGDD-SSGD----------------K

ENSGT00530000063436_0_Linker_2_3 (526, 538)

SNVDLHVLK--P

PF07686 // ENSGT00530000063436_0_Domain_3 (538, 655)

EPE
LVYA-----------DLGSSVRFDCALGPE-VVNVAKF------------LCQKNKEKTC
NLVANTLGQWNQAFKGRILS-QNN--NGVFSVDVTNLRKED-AG---PYLCGAN

ENSGT00530000063436_0_Linker_3_4 (655, 682)

SDGQPR
KSRPSQAWQ-LFVNEETTFPS

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 784)

RPSVVKGVVGGSVAVLCPYNPKE-----VNSVKSWCRWE
DIQ-NSGCPPLVQSTGLVKNQYEQYNGR---LVLYDEPGNGT--YTVILNQLTAQDAGFY
WCL

ENSGT00530000063436_0_Linker_4_5 (784, 812)

TNGDIHWRSMVELKIVEG--QPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 908)

-PKTVNVELGE--TVQLTCHSPCKFYS--
-YKKFWCKWTDQG--------CSALPSQDEGSGQAVVNCDQNSQLINLTLKQVTKGDEGW
YWCGVKEGLQYRETVAVYVAVKEK-GTEGQRP--S-------------SLS---SV-RAA
AAEDEIETSVR------KVES----------------------EVVQDPRLSVDTQE--K
DPEDAAGGSIASAD-PGSSAGQG--GSSKVVVSTLVPLA--LV-LALGVLVVGVLRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFGANDNMGASPV--SQETTLGGKDEF--
-IAT--------TENTVETEEPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQANNMAA-NIQDSP--SKA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWLLYFLPV--------SGALRVLPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

QLDV
EWGGSIIIECPLP-----QLHVRMYLCRQMAN-PGICSTVVSN----NFVKKEYERRVTL
KPC-----LDKKLFLVEMTQLTENDNGIYACGMGMKTDKG--KTQ---------KIILNV
HNE-----YP----EPFWEDEW-----TSER--------SRWLHRFLQH--QM--P---W
LHGSEHPSSSGVIAKV---------TTPT--PKTEAPPVHQPSSITS--VTQH--PRVYR
AF----------------------------------------SVSATKSPALLPA-----
----TTA-SKTSTQQA-IRPLEASYSHHTR-LHEQRTLHHG--------PHYGRE-DRGL
HIPIPEFHILIPTFLGFLLLVLL----GLVVKRAIQRRR-A-SS-RRAGRLAMRRRGRG-
A---SRPFP-T------QRRD----------------APQRPRS-----QNNVYSACPRR
ARG----PDSLG------------PV-E----APLLNAPA-----S--------------
-----------------------ASPASP--QVLEAPWPRAP--SLKMSCEY------VS
LGYQPAVNLEDPD--SDDYINIPGPSHLPSYAPGPRSSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWLIYFLPT--------VS

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

GALVLPEVKLEG
MLGGSITIECPLP-----ETYTRVYLCREIDK-SEACFTVVSS---KRFVRKEYKHRITL
TPY-----PDQNLFLVELTELTQSDSGVYACGTGSNTDRG--KTQ---------KVTLDV
HSDYAS--A--------IIVSP-----II-T--------GVWIGG---------PR---R
GSDPFHISAESCLXAV---------PSPA--PMTEAPPAHHSSPTTP--ATHR--PRVPR
SS----------------------------------------AVAAAKPTTRLPS-----
----TTS-SKTSAPERLLRPPTASYNQHTR-LHRQRASHHG--------PASRME-DQ--
-----GFHLLIPTFLSLILLSLL----GLLVTRIIQRKK-A-LS-RRARQAGRRARVGP-
D---PPPPP-G------HDPR--------------------PRP-----H----------
--------PGLRFLP----PG---DL-E----APTLGPGA-----S--------------
-----------------------APPAPP--QVSEAPWPHVP--SLKTSCEY------MS
VYHQPAAMMEDAD--SDEYVNIYC------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTPF-----------------LLACLLAAFPAV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 334)

PQQVRG
VEGKSASITCFYPP-TSVNRHTRKYWCRQGA--SGPCTTLISS---EGYVSSNYVGRARL
TNF-----PENGTFVVDIAQLFRNDSGRYKCGL

ENSGT00530000063436_0_Linker_1_2 (334, 388)

GLN-SRG--LSF---------DVSLEV
SQD--------------PGLLKDTDVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 494)

TVDVGRTV--TI-------------------KC
PLTSTNGHLKRSLCKWR-GQHCVTVIDTN---YVS------SEYGGRISLPIQ-GTDQST
FSVIIKQLRLSDAGK---------------------------------------------
------------------------------------------------------------
-----------------------D-QGRLFNVLITGLRKED-AG---RYVCGAHSDGVLQ
DGWPIQAWQ-LFVNEETTIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QSPSVVKGVTGGSVSVLCPYNPKE-----GSASKYWCRWD
GAESSGRCPLLVESQGLVKEQ---YKGR---LVLHEEPGNGT--YTVILNQLTAKDAGFY
WCLTNRDIRWRTSMELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VIE--GKPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PENVTAVLGG--SLKLPCHFPCKFYS--
-HEKYWCKWSNSG--------CQALPTQDEGPSQAFVNCDQNSKVISLTLNQVTKADEGW
YWCGVKEGQLYGETAAVYVAVEEK-VQGSRSG--S-------------PENA-----NVP
PGEDLLEASAS--------E---T-----------------ENRAVQGPRLFAEERV-VE
DVEDQAEGSRASAD-ASGSEGQG--GSSKVLLSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----ASYRTNISMSDFE-NSREFGANDNMGASPV--TQETSLEGKDEL--
-STTNEST--------TETGEPKKAKR---------------------------------
-SSKEEA-EMAYSAFLLQASNVAT-EAQDKP--AEV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MSRL-----------------FLACLLAVFPAVSA--PTAVSMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 344)

PIFGPEEVTS
VEGRSVSITCYYPA-TSVNRHTRKYWCRQGA--KGRCTTLISS---EGYVSDDYVGRANL
TNF-----PESGTFVVDISHLTRNDSGRYKCGLGIS-SRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 388)

NF---------DVSLEV
SQD--------------PAQASDAHIY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 503)

PVDVGRTV--TI-------------------NC
PFTSANSQKRKSLCKKT-GQDCFLIIDST--GYVS------GSYTGRIRLNIA-GTNTLM
FSVVINRVPLSDSGMYVCQAGD

ENSGT00530000063436_0_Linker_2_3 (503, 559)

D-AKAD----------------KSNVYLQVLE--PEPE
LVYR-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 654)

SSVTFDCSLGPE-VADTAKF------------LCQQKNGEAC
NVVINTLGKKAQDFQGRILFLPKD--NGVFSVHIASLRKED-AG---RYVCGA

ENSGT00530000063436_0_Linker_3_4 (654, 681)

QPEGQPE
EGWPVQAWE-LFVNEETAIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

ASPSVVKGVKGGSVTVSCPYNPKD-----ANSAKYWCRWE
ETQ-NGRCPRLVQSKGLVKEQ---YKGR---LALLAEPGNGT--YTVILNQLTDQDTGFY
WCVTDGDTSWTSTVQLK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVEG--EPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 912)

-PKNVTAWLGE--AFKLSCHFPCKFYS--
-FEKYWCKWSNEG--------CSPLPTQNDGPSQAFVSCDQNSQIVSLNLDTVTKEDEGW
YWCGVKEGPRYGETAAVYVAVESR-AKGESPR--A-------------RP----TC--PR
--KGMRSPHNP------RIPNEAPL-RRLPKFKPLSA--LPRVPRRQDPRLFVEEIA-VK
D---AAGGPGAPAD-PGRPAGHS--GSSKVLVSTLVPLA--LV-LAAGVVAIGVLRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFEGRDNMGASPE--AQETSLGGKDEF--
-ATA--------TEDTVESKEPKKAKR---------------------------------
-SSKEEA-DEAFTTFLLQAKNLASTTTQDGP--TEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MNLWLWSLYFLPV--------

PF07686 // ENSGT00530000063436_0_Domain_1 (227, 361)

SGALKTLPAVNLEG
ELGGSIIFKCPLP-----EKYTRVYLCREMAA-SGACATVVSN---GNYVKNGYAGRVTL
NLL-----TDSHLFLVEMTEITENDSGVYACGVGTNTDRG--KTL---------QITLSV
SSRYPP----PTEYQPFWEKEL-----TLET--------PGWFHRLLYLTTASVPP---W
FQMLEDAIPSEFISKV---------TTPA--QRPQTPPAHRSSSDTP--VIHG--PPIST
AS----------------------------------------LVAAGKPPTLLPS-----
----ITA-SKTSAQEEQVGPQPASYNRQTR-LHRQRGQHYGPPIKNSSHGLSGSE-DQ--
-----GFHILIPTILGLMLLALL----GIVVKRAIQRRR-V-LS-RRIRRLAVRMRALE-
V---SQRPR-S-----WQRPR----------------VSQRQRS-----Q-NIYSACPRR
ARG----ADPAG------------AG-Q----EPLPGRGA-----P--------------
-----------------------EPSAPP--QVPEAPWFHAP--SLKASCEY------VS
CYHQPPAKMEDYN--SDDYINISCLTHLPSCPPRSRPLCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------LLPLSAV--------SGAMKIFPQVN

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LDG
PLGESVVIKCPLA----GEIGVRMYLCRQMPS-SGMCATVVSN----NFVKEEYRDRITL
LPS-----PDKTHFLVEMSELTESDSGVYACGLGFNTDRD--KTQ---------KVILNV
HDE----------YEPFLEEE-----------------LQPWFSKLPEQ--QI-PY---W
PQEHSFLLP---SFAV---------AIPA--QRTEAAPVHHSSTTTP--TTHQ--PRASA
AS----------------------------------------PAVAAKLPTLLPP-----
----TEA-SESSAQERVLGPQEASYKYHTW-LYRQRFRHHHPQK---SKISARWE-DQ--
-----GFHIVIPSVLGFLLLALL----GLLLRRAVQRRR-A-FS-RRIRRLAIRMRGME-
A----SGRP-G-----SRQPR----------------AGPRPRS-----QNNVYSACPRR
APS----PEEAP--------------------------PP-----E--------------
-----------------------SGSAGP--SMPETPWLRAP--SHKASCEY------VT
ICHQPAAQREDPDSAEDDYINVPSLTFLPRCPPAPSPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPWLWLLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
QLGGSVTIRCPL-----PETPVRIYLCREMAE-PRTCATVIST---TNFIKNEYRGRVTL
TEN-----PHENLFLVKVAELTESDSGVYACGAGINTDRG--KTQ---------KVTLNV
HSE----------YEPLWKEQP-----APET--------PNWF--------HL-LH---L
FQMPAHASSSKSVPR---------------------------------------------
------------------------------------------------------------
------A-SEISARGVLLKPRTVGYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTVLGLSLLALL----GLMVKRAVQMRK-A-LS-RRARRLAVRMRALE-
S---SQPPR----------------------------GSQQKRS------QNIYSACPRR
APG----ADAAG------------NG-E----TLVPGFRE-----P--------------
-----------------------LSPALL--QVSESPWLHTP--PLKTSCEY------VS
LYFQPAAKMEDGD--SNDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRPL-----------------FLACLLAVFPVV--------STKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 334)

PIFGPQEVNI
VEGGSASITCYYPA-TSVNRHTRKYWCRQGA--KGRCTTLISS---DGYVSKDYEGRANI
TNF-----PDSSTFVMNIDHLTQNDSGRYKCGL

ENSGT00530000063436_0_Linker_1_2 (334, 386)

GIN-SRG--LSF---------DVSLDV
SKG--------------PGPLGDTE

PF07686 // ENSGT00530000063436_0_Domain_2 (386, 530)

VYTADLGGTV--TI-------------------NC
PFKPENSEKKKSVCKKT-DKGCVTVIDST--GEVN------SDYGGRIELEIM-GTDQLT
FSFIIKQVQLSDAGRYVCQIGED-TIGE----------------KSNVD

ENSGT00530000063436_0_Linker_2_3 (530, 560)

LQVLK--PEPN
LLYG-----------DLRG

PF07686 // ENSGT00530000063436_0_Domain_3 (560, 662)

SVIFDCALGSD-VENMAKF------------LCRMSNEEAC
DVVINTLGKKDRSFEGRILLIPKN--KRSFSVHITNLRKED-AG---NYLCGAHSDGEPQ
K

ENSGT00530000063436_0_Linker_3_4 (662, 680)

GSPIQAWQ-LFVNEETVI

PF07686 // ENSGT00530000063436_0_Domain_4 (680, 785)

PPSPSVVKGVVGGSVAVFCPYKPKE-----TNSLKYWCRWE
DTQ-NGLCRSLVESDGGVTEQ---YEGR---LALHEEPGNGT--YTVILNQLTANDAGFY
WCLT

ENSGT00530000063436_0_Linker_4_5 (785, 813)

NGDTHWRSMVKLQVVEG--EPSLKV---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 918)

PNNVTALVGE--TLKLPCHFPCKYYS--
-YEKYWCKWSNKD--------CKILPSQGEGPSDAFVNCDQNSQIVSLSLDPVSKEDEGW
YWCGVKNGLRYGETMAVYVAVKEK-VKGSQDV--S-------------QV----N---AA
PGEEAVESNVR------KVES----------------------KVVQNPRLLVDNVA--V
ETGDAAGGNRASVD-TSSSAGQS--GTSKVLLSTLVPLG--LV-LAVGAVVVAVLRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFGANDNMGASQV--IQETTLEGHDEC--
-SAATT-----TTEKTMESEEPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQTNNMAA-DVQEGH--GEA---------

------------------------------------MDQGA-----PAKPSEQKHLTCQD
TQFPGPAFRVEL---------PSYWSKLRMHSQSAEPWTPDHSLQLLTSLPLASCL---W
LQVPSLRTRWEI-LLLTLCLLHGSSMTPPHRRSHSRWL----------------QAGSP-
--QFRTHLYN-----VEAHTAPTP----LCCW-K-NSL--------SGTNALR

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVTG
NTGGAVTIHCHYAP-SSVNRHQRKYWCRLGSP-LWICHTVVST---NQYTHPDYRGRAAL
TDI-----PQSGLFVVRLLRLSLGDVGLYRCGIGDRND-M--LFF---------SVNLTV
SAGPSN--TTYAA-APASGE-----PTTASPGAASSA-GNGWTSGI--------------
----------------------------T--QILEGSGSEWDRT----------------
-----------------------------------------------------VP-----
----TTGTSKTTSSA---------------------------------------------
------------------------------------NGRQTLRT-ARTMVPGTGSREEG-
S----IRAA-V------PTPEG-------------------PSPKSRSMSSTTQGVWLWS
TRN----SV--TPSVT---TS---EGRRQGTTPETDGPRDET--D---------------
--------VRVSPEAPRKTTGTTRPSAL----ISE----HVTWETLQDK-----------
---TEVS-------------KQQMLHSLEELSPAPSAQTLNAT-----------------
------------CL-EVAS-EEGRSIDGSLE----------------------NTT----
-----EES-SPPTPSQLSVAG------------PVW--VS--------------------
-------VKGPSM--KSALMEGE--SHTRIL----TPVS--TVLALLLIAALILLKRSLG
RQRT----SQKKERVPRITLIQMTHF------LPD-KLPDEGK-------NFQQ-SNL--
-LPPQASL-----TVLENDPRP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVNS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--RGGCITLISS---EGYVSSKYAGRANL
TNF-----PENGTFVVNIAQLSQDDSGRYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PGLLNDTKV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDLGRTV--TI-------------------NC
PFKTENAQKRKSLYKQI-GLYPVLVIDSS--GYVN------PNYTGRIRLDIQ-GTGQLL
FSVVINQLRLSDAGQYLCQAGDD-SNSN----------------KKNADLQ

ENSGT00530000063436_0_Linker_2_3 (532, 558)

VLK--PEPE
LVYE-----------DL

PF07686 // ENSGT00530000063436_0_Domain_3 (558, 664)

RGSVTFHCALGPE-VANVAKF------------LCRQSSGENC
DVVVNTLGKRAPAFEGRILLNPQD-KDGSFSVVITGLRKED-AG---RYLCGAHSDGQLQ
EGS

ENSGT00530000063436_0_Linker_3_4 (664, 682)

PIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 787)

SPTVVKGVAGGSVAVLCPYNRKE-----SKSIKYWCLWE
GAQ-NGRCPLLVDSEGWVKAQ---YEGR---LSLLEEPGNGT--FTVILNQLTSRDAGFY
WCLTNG

ENSGT00530000063436_0_Linker_4_5 (787, 812)

DTLWRTTVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWNNTG--------CQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGW
YWCGVKQGHFYGETAAVYVAVEERKAAGSRDV--S-------------LAKA-----DAA
PDEKVLDSGFR--------E---I-----------------ENKAIQDPRLFAEEKA-VA
DTRDQADGSRASVD-SGSSEEQG--GSSRALVSTLVPLG--LV-LAVGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKEEF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQSSTVAA-EAQD-----------GPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------ALTCLLVAFPAV--------STKSPVFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--SGRCITLISS---EGYVSNSYTGRANL
TNF-----PENGTFVVNIAQLSRDDSGRYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SRD--------------PGLLNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------NC
PFKSEDAQKKKSLYKMI-DQTPVLVIDST--PYVS------PDYRDRIHLDIH-GTGQLM
FTVVINQLRLSDAGMYVCQAGAD-SRAD-----------------KNVDLQVLA--PEPE
LVYG-----------DLRGSVTFNCALGPE-VANLPKF------------LCRVSNGEHC
DVLINTLGNRAPAYEGRILLSPKD-KNGLLSVLITGLRKED-AG---RYLCGAHPDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVVGGSVAVVCPYNPKE-----SKSIKYWCRWE
GAR-NGHCPLLVESDGLVQEQ---YEGR---LALHQEPGNGT--YTVILNQLTSQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 913)

-PGDVTAVVGE--SLKLLCHFPCKFYS--
-YEKYWCKWSNKG--------CQALPSQDEGPSQALVNCDQNSRVVSLTLNPVTKADEGW
YWCGVKQDHSYGETAAVYVAVEEKKVAGSRDA--S-------------PAKV-----DAA
PDEKVLESGVQ--------E---I-----------------ENKAVQDPRLFAEEKA-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSRVLVSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDGF--
-VATTENT--------TETKEPKKAKR---------------------------------
-SSKEEA-EMVYRDFLLQSSAVAA-EAQDGP--RE---------A

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRLF-----------------VFTILLAVLPAV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

PQDVSS
VVGNSVSVTCYYPA-TSVNRHSRKYWCRQGA--SGLCTTLISS---NGYISKEYAGRAKL
INF-----PENSTFMVNIAELTQNDTGSYKCGLGTS-NRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 388)

FF---------DVSLEV
SQA--------------PELPVDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TKDLGRKV--TI-------------------TC
PFKKENAHSKKSLCKKT-GQTCELVIDST--EYVN------PKYKGRTTLFMK-GTNPEL
FTVDIDHLRPSDAGLYVCQAGQD-SSAD----------------KNNVDLQVIE--PKPE
LVYG-----------DLRASLAFNCDLGRE-VANEAKY------------LCRMN-KETC
DVIINTLGKRDPAFEGRILLTRKD-DNGRFSVLITGLRKED-AG---HYLCGAHSSGLPQ
EGWPIQAWQ-LFVNEESIMPPSR

PF07686 // ENSGT00530000063436_0_Domain_4 (684, 798)

SVVKGVTGGSVAIVCPYNPKE-----SSSLKYWCRWE
ADG-NGHCPVLVESQGVVHEQ---YEGR---LALYDQPGNGS--YTVILNQLTTQDSGSY
WCLTDGDSRWRSTVELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VAEATGKPNLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 912)

TPQNEVAVLGE--TLTLSCHYPCKYYS--
-HEKYWCKWSNKG--------CRILPSHDEAARQSSVSCDPNNQVISMTLNPVTKEDEGW
YWCGVKKGQVYGETTAIYVAVEEK-TGGSRQV--S-------------PVDANAPA-NVA
PEEEVAESDVS--------E---N-----------------ENKAIPNPSLLEKEGE-ID
IVGDQVQENRAAVD-AGSADGPK--GSSKVLFSTLVPLG--LV-LAAGAVAVWVARARHR
--KNVDRMSI----SSYRTDINMADFK-NSRDFGGNDNMGASPD--IEETVLERKDEI--
-VTTTETA--------TEPEESKKAKR---------------------------------
-SSKEEA-DLAYSTFLFQSSNIAA-QVHNGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------ALTCLLVVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 336)

PQEVSS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--SGRCTTLISS---EGYVSNSYTGRANL
TNF-----PENGTFVVNIAQLSRDDSGRYKCGLGI

ENSGT00530000063436_0_Linker_1_2 (336, 387)

N-GRG--LSF---------DVSLEV
SQD--------------PGLLNNTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------NC
PIKSEDAEKKKSFYKMI-GENPVLITDTT--SYVS------PNYKGRIHLDIH-GTDQLM
FIIVINQLRLSDAGMYFCQAGVD-SQAD----------------KKNVNLQVLA--PEPE
LVYG-----------DLRGSVTFNCALGPE-VANLPKF------------LCRVSNGENC
DILINTLGKRAPAFEGRILLSPKD-KNGLLSVLITGLRKED-AG---RYLCGAHPDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVVCPYNPKE-----SKSIKYWCRWE
GTQ-NGHCPLLVESDGLVQEQ---YEGR---LALHQEPGNGT--YTVILNQLTSQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 910)

-PGNVTAVVGE--TLKLPCHFPCKFYS--
-YEKYWCKWSNKG--------CQALPSQDEGPSQAFVNCDQNSRLVSLTLNPVTKADEGW
YWCGVKQDHAYGETAAIYVAVEEKKVAGSRDA--S-------------PAKA-----DAA
PDEKVLESGVQ--------E---I-----------------ENKAVQDPRLFAEEKA-VA
DAGDQAGGSRASVD-SSSSEEQG--GSSRALVSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----GSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDGF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMVYRDFLLQSSTVAT-EAQDGP--RE---------A

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MSRL-----------------FFACLLAVFPVV--------SM

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

KSPIFGPQEVSS
VEGSSVSIKCYYPA-TSVNRHTRKYWCRQGA--RGRCTTLISS---EGYVSKDYEGRANL
TNF-----PESGTFVMNIGHLTRNDSGLYKCGLGIS-SRG--LSF---------DVNLEV
SQA--------------PGQINGVHVYTAELGRKV--TI-------------------NC
PFRAMNSEKKKSVCKKT-GQSCVLVTDST--GYVS------PSYSNRVHLNIQ-GTNELA
FSVEINHIQLNDAGMXXXXXXXX-XXXX----------------XXXXXXXXXX--XXXX
XXXX-----------XXXXXXXXXXXXXXXXXXXXXXX------------XXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXK--DDGFRVLVTSLRKED-AG---LYLCGANPDGEPQ
EGWPTQAWQ-LFVNEETMIPPSQPVVKGVV

PF00047 // ENSGT00530000063436_0_Domain_4 (691, 784)

GGSVAVSCAYNPKD-----TDSLKYWCRWE
DTQ-GGHCPNLVESKGPVKEQ---YEGR---LALYEEPGNGT--YTVILNQLTTQDAGFY
WCL

ENSGT00530000063436_0_Linker_4_5 (784, 821)

TSGDTRWMSTVELKVVEG--EPSLKV---PKNVKAWL

PF00047 // ENSGT00530000063436_0_Domain_5 (821, 905)

GE--TLKISCHFPCKFYS--
-YEKYWCKWSNKG--------CRTLPSQDEGPSQAFVNCDQKSQVVSLNLTSVTSEDEGW
YWCGVKEGHKYGETVAVYVAVEKR-VKGSQDT--S-------------RV----N---AA
PGEEAIEPRAR------ETEN----------------------KVIQGPSLFSEKRA-VK
DVGGPAGGSGAPAD-PGSSAGQG--GSSKALF-TLVPLA--LV-LAAGAVAIAVVRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFGAHDNMGASPD--TQETTLGGKDEF--
-ATT--------TEDAVEKEEPKKAKR---------------------------------
-SSKEEA-DMAFTTYLLQTNNMAA-ATQNGP--REA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWLLYFLPV--------SGALRVLPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 361)

LDV
EWGGSIIIECPLP-----QLHVRMYLCRQMAN-PRICSTVVSN----NFVKKEYKRRVTL
KPC-----LDKKLFLVEMTQLTENDNGIYACGMGMNTGRG--KTQ---------KITLNV
HNE-----YP----EPFWEDEW-----TSEP--------PRWLHRFLQH--QM--P---W
LHRSEHASSSGVIAKV---------TTPT--PKTESPLVHQPSSIAP--VTQH--PRVYR
AF----------------------------------------SVSATKSPALLPA-----
----TTA-SKTSTQQA-IRPLEASYSHHTR-LHEQRTLHHG--------PHYGRE-DRGL
HIPIPEFHILIPTFLGFLLLVLL----GLVVKRAIQRRR-A-SS-RRAGRLAMRRRGRG-
A---SRPFP-T------QRRD----------------GPQRPRS-----QNNVYSACPRR
ARG----PDSVG------------PA-E----APLLNAPA-----S--------------
-----------------------ASPASP--QVLEAPWTHAP--SLKMSCEY------VS
LGYQPAVNLEDPD--SDDYINIPGPSHLPSYAPGPRSSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHVRMYLCREMVE-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVGDEPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWFHAP--SLKSSC--EY----VS
LYHQPAAKMEDSN--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTLF-----------------LLAFLLAFFPGA--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

PAEVSS
VEGNSVSIKCYYPN-TSVNRHTRKYWCRQGA--SGHCMTLISS---EGFVSKDYAGRANL
TNF-----PETSTFVVNITQLSRDDSGSYKCGLGVN-

ENSGT00530000063436_0_Linker_1_2 (338, 388)

GRG--LSF---------DVSLEV
SHA--------------PEL-DDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TEDVGRTV--TI-------------------SC
PFKRENAKNKKSLCKKT-GQVCDVVVDSI--GNTS------PSYKDRITLFIQ-GTSQTE
FKVIINHLRPSDAGMYVCKAGDG-SSAN----------------TKNIDLQVLE--PEPE
LVYG-----------DLRSSVTFDCALGPE-MANEAKF------------FCQMSKEGTC
DVIINTLGQRNPAFEGRILLTPKE-NNGRFSVLVTGLRKED-AG---RYLCGAHPSGLLE
EGWPIQAWQ-LFVNEETTMP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QTRSVVKGVEGGSVSVLCPYDPKE-----SNSLKYWCRWE
GIQ-NGRCPLLVESQGLVQDQ---YEGR---LALFEDPGNGT--YTVILNKLTSQDAGFY
WCLTNGGSRWRTTTELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVEAPGEPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 909)

-PKQVTAVLGG--SVTIPCHFPCKFYS--
-YEKYWCKWSNRG--------CQALPSQEERPKAASVGCDQNSRLVNLTLNPVSKKDEGW
YWCGVKQGHTYGDTAAVYVAVEET-AEGSRDV--S-------------QVNT-----NAA
PKVKVAEPGAR------ELT---P-----------------DNTAIVNPRLNVEETV-LE
ERGDQAQEGRASAG-AGSSEGHG--RSSQVLLSTLVPLG--LV-LTVGAITVWVARVRHR
--KNVDRISL----QSYRTDISMADFN-NSRDFGGNDNMGASSV--TLETDLEAKREL--
-ETTTKVP--------EDPEEPKKAKR---------------------------------
-SSKEEA-DMAYSAFLFQSNNIAA-QLEDGP--REA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRLY-----------------LFTLLVTVFSGV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 340)

PQEVSS
IEGDTVSITCYYPD-TSVNRHTRKYWCRQGA--SGMCTTLISS---NGYLSKEYSGRANL
INF-----PENSTFVINIEQLTQDDTGSYKCGLGTS-NR

ENSGT00530000063436_0_Linker_1_2 (340, 388)

G--LSF---------NVSLEV
SQV--------------PELPSDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 533)

TKEIGRNV--TI-------------------EC
PFKRENAPSKKSLCKKT-NQTCELVIDST--EKVN------PSYIGRAELFMK-GTDLTV
FYVNIRHLMHNDAGLYVCQAGEG-SSSD----------------KKNVDLQVLE--PEPE
LLYK-----------DLRSSVTFECDLGRE-VANEAKY------------LCRMN-KETC
DVIINTLGKRDPAFEGRILITPKD-DNGRFSVLITGLRKED-AG---HYQCGAHSSGLPQ
EGWPIQTWQ-LFVNEESTIPNHRS

PF07686 // ENSGT00530000063436_0_Domain_4 (685, 798)

VVRGVTGGSVAIVCPYNPKE-----SSSLKYWCRWE
GDG-NGHCPVLVGTQAQVQEE---YEGR---LALFDQPGDGT--YTVILNQLTTEDAGFY
WCLTDGDSRWRTTIELQ

ENSGT00530000063436_0_Linker_4_5 (798, 813)

VAEATREPNLKV--M

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 911)

PQNTTAVLGE--TFTVSCHYPCKFYS--
-QEKYWCKWSNKG--------CHILPSHDEGARQSSMSCNQSSQLVSMTLNPVSKEDEGW
YWCGVKQGQTYGETTAIYVAVEER-TRGSSHV--N-------------PTDANARA-KVA
PEEEVVDSSIS--------E---K-----------------ENKAIPNPGPFANERE-IQ
NVGDQAQENRASGD-AGSADGQSGSSSSKVLFSTLVPLG--LV-LAVGAIAVWVARVRHR
--KNVDRMSI----SSYRTDISMADFK-NSRDLGGNDNMGASPD--TQQTVIEGKDEI--
-VTTTECT--------AEPEESKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSTIAA-QVHDGP--QEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------

PF07686 // ENSGT00530000063436_0_Domain_2 (383, 533)

DSEVIITEVGKTV--SI-------------------NC
PFKEENVQDRKFLCKKD-DKSCALVIDSQ--NNVG------SDYTERVRFRIS-GTSSKV
FVVIISQFKRQDVGTYICAVGEDSAPKI----------------QKTVDIKL

ENSGT00530000063436_0_Linker_2_3 (533, 539)

LD--PE

PF07686 // ENSGT00530000063436_0_Domain_3 (539, 674)

TE
LVYA-----------EQGGSVTLNCALGST-AENMPMY------------LCRK-GRHDC
DLVINSKGFTNNSTHGRILFTPT--EPGSFSIMITQVRKED-AG---LYHCGAQENGEPS
EKGPIQALQ-LFVSEETTVPKSPLVVKGPSGGSVSVTCHYDPKK-----NNTLKYXXXXX
XXX---XXXXXXXXXXXXXXX---XXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXX--QSLLKT---PKTVTAQL

PF00047 // ENSGT00530000063436_0_Domain_5 (821, 905)

GQ--SLTVSCHFACKLYS--
-YEKYWCKWSNQG--------CENLPTQEEGSSQAFVDCNQDSRIVSLTLNPVTRAHEGW
YWCGAKKGQNYGQTTAVFVSVEEKXXXXXXXX------------------X-------XX
XXXXXXXXXXX--XXXX---------XXXXXXXXXXX----------------XXXX-XX
XXXXXXXXXXXXXX-XXXKEEQG--GGSSLLVSTVVPVA--LV-LTVGAVALGVIKARRG
--RFSDRVSI----GSYRTDISMSELERNPRQFGANDNMGSSIQ---ES-TLEGEIEF--
-ITQTENP--------EEIQEPKQVKR---------------------------------
-SSKEEA-DMAYTAFLLQANNMASEIPLDGH--SDA---------

------------------------------------MDGEA-----TLKLREQKEVARRG
TEV-DYS------------------------------------------RLIAGT-LPQS
HVAN-RKAGWKMPFFLIPCLLQGSSFALPQERPHPRWL----------------WEGSL-
--PSRTHLRT-----MGTLRPSSP----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIRCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVYT---SHYTHHHYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWTPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGSQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAAKSRSMSNTTEGVWG-G
TRS----SV--TNGAR---AS---KDRREMTTTKADRPKEDT--ER--------------
--------VRITLDAAKNVLGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYVGETTPAVGLWTLGTPAAGV------------W
T-LGTPAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRI---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAQASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------

PF07686 // ENSGT00530000063436_0_Domain_1 (227, 361)

STTLEPLEEIMLYG
ELGGSIDIRCPLK-----NPPQKYYLCREIS--PGQCSTVVSS---TSFVGPDYQNRVSL
KLL-----PEEMVFLVELRNLKEEDSGSYACGICKKRDKR--KTL---------KVILTV
SP----------------------------------------------------------
---------------------ASTSAPWT--QPGQTQPPLDPSPTSPIC-L--------R
AT----------------------------------------LAAAPTFQTSRSS-----
------VTSKSLHLRRLLRPSTVSYSHNTR-LRGESASYFG---------SSMKK-DG--
-----GFHILIPATLGIILMMLL----GLVLGRSLQKRR-V-LS-RRINRLTMRMSALE-
A---SQRTH-EAL---------------------------LPRS-----QYNIYSACPRQ
VQR----PNXXXXXX----XX--------------XX--X-----X--------------
-----------------------XXXXXX--XVSKTAQLQAP---VPVKNEY------MS
TYSLCVSEQEDSD--SHDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHVRIYLCREMVG-SGTCGTVVST---TNFIKAEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVIRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVVGDKPPTFLPS-----
----TTT-SKISALERLLKPRTASYNHHTR-LHRQRALDYG--------SRSGRE-GQ--
-----GFYILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSRLPRS-----QNNIYSACPRR
AGG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWFHAP--SLKTSCEY------VS
LYHQPATQMEDSN--SNDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDAEA-----TVKSREQKASFHLQ
------C------------------------------------------FL---------
-QVTSRRAGWKMPFFLMLCLLQGSSFALPQKRPHLRGL----------------WEGPL-
--PSRTHLQA-----TGTLMPSSP----LCWR-EGSSF--------AAANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
DPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPS-RWICQTIVST---NHYIHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPEDVGCYLCGIGDENN-L--LFF---------SMSLTV
SAGPSS--TLP-TATPAAGE-----LPMRSYGTASAV-ANRWTPGT--------------
----------------------------T--QT-LGQRTSWNTV----------------
-----------------------------------------------------VS-----
----APGTSVTRASA---------------------------------------------
------------------------------------KGKQTSGA-TRPAAPGTGSWAEG-
S----AKAP-A------PIAES-------PPSES-----------RSRMFNTTEGVWG-S
TRS----SV--TNK-----AS---KDGREMTTTKVNRPREDT--ER--------------
--------VRIAPEAAKKALGTVSPPAP----VSE----TLGWEILPQCCLE--------
---TSVS-------------RQQSLGPMGETTPAAGVWTLGTA-----------------
------------SI-EAAS-GEG-SVAGDLD----------------------AAP----
-----GDRGSQATPSQALAVG------------PWR--PP--------------------
-------GKESSV--KSAFAEDE--SNSWTL----APVS--TLLGLFMLMALVLLQRKLR
R-RKT---SQEAE---RVTLIQMTRVL-AVNLQPD-QLPHVKR-------KTLQ-DDS--
-LPTGTSL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MRLY-----------------LFTLLVTVFSGV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 340)

PQEVSS
IEGDSVSITCYYPD-TSVNRHTRKYWCRQGA--SGMCTTLISS---NGYLSKEYSGRANL
INF-----PENNTFVINIEQLTQDDTGSYKCGLGTS-NR

ENSGT00530000063436_0_Linker_1_2 (340, 389)

G--LSF---------DVSLEV
SQV--------------PELPSDTHVYT

PF07686 // ENSGT00530000063436_0_Domain_2 (389, 532)

KDIGRNV--TI-------------------EC
PFKRENAPSKKSLCKKT-NQSCELVIDST---KVN------PSYIGRAELFMK-GTDLTV
FYVNISHLMHNDAGLYVCQAGEG-PSAD----------------KKNVDLQ

ENSGT00530000063436_0_Linker_2_3 (532, 557)

VLE--PEPE
LLYK-----------D

PF07686 // ENSGT00530000063436_0_Domain_3 (557, 657)

LRSSVTFECDLGRE-VANEAKY------------LCRMN-KETC
DVIINTLGKRDPDFEGRILITPKD-DNGRFSVLITGLRKED-AG---HYQCGAHSS

ENSGT00530000063436_0_Linker_3_4 (657, 685)

GLPQ
EGWPIQTWQ-LFVNEESTIPNRRS

PF07686 // ENSGT00530000063436_0_Domain_4 (685, 798)

VVKGVTGGSVAIACPYNPKE-----SSTLKYWCRWE
GDG-NGHCPVLVGTQAQVQEE---YEGR---LALFDQPGNGT--YTVILNQLTTEDAGFY
WCLTNGDSRWRTTIELQ

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VAEATREPNLEV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

TPQNATAVLGE--TFTVSCHYPCKFYS--
-QEKYWCKWSNKG--------CHILPSHDEGARQSSVSCDQSNQLVSMTLNPVSKEDEGW
YWCGVKQGQTYGETTAIYVAVEER-TRGSSHV--N-------------PTDANARA-KVA
LEEEVVDSSIS--------E---K-----------------ENKAIPNPRPFANERE-IQ
NVGDQAQENRASGD-AGSADGQSRSSSSKVLFSTLVPLG--LV-LAVGAIAVWVARVRHR
--KNVDRMSI----SSYRTDISMADFK-NSRDLGGNDNMGASPD--TQQTVIEGKDEI--
-VTTTECT--------AEPEESKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSTIAA-QVHDGP--QEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MF--TS-----LTNALLPSFPKE--------PA

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 355)

SSTLYGPRFLTG
AVGGSITHQCFYSI-TPANRHDRKFWCKRKR--DGICYTIIST---TNFIAEDHMGRVAL
EDV-----PQNGTFMVTMTQLKASDTGTYRCGIGPT-NSN--LYV---------

ENSGT00530000063436_0_Linker_1_2 (355, 361)

SLNLTV

PF07686 // ENSGT00530000063436_0_Domain_2 (361, 529)

SAD--------------VGTQRPVELFLGEL-RGS-VTI-PC------------PPGDSW
----GG--TRRLWCRVG-RSSCILIADTD--GYVG------KSYEGRIHITPQ--ESSGA
FKVLINDLRPEDMGLYTC---GMGSPA---IRDR--------NSEVEV

ENSGT00530000063436_0_Linker_2_3 (529, 530)

G

PF07686 // ENSGT00530000063436_0_Domain_3 (530, 672)

PDIPEE---AE
LFYV-----------ELQGSVSMACDFGGD-YASTRKF------------FCKME-KSGC
RNIVDTYGKIDPDFQGRVLLSNDN-TEGAFSIMITQVGWED-AG---LYLCGVGSYGEYG
K---TKELS-V

ENSGT00530000063436_0_Linker_3_4 (672, 691)

HVYEGTKAPQEKDTVFGIK

PF00047 // ENSGT00530000063436_0_Domain_4 (691, 784)

GSSATIDCNYDPTK-----NYTLKYLCKWR
TTG----CARIIDNTGFLSIP---YEGR---VAMFDNPKNGT--FSIILNQLRSSDEGFY
WCM

ENSGT00530000063436_0_Linker_4_5 (784, 804)

TNDHRERKTSKELKIIE--G

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 922)

EPGLTG---KEEVQAEVGS--RVDLTCSYSCKYYS--
-YEKYWCKWSSDG--------CTPLTASDQSQPGLDVSCDTANKTLILSLDPVTVEDQGW
YWCGVRRNGHYGETMAVSLQVDG-VPYEQARGSAS---ASGSILDCSNLTTLLTSTMQEI
SSEQQKEQKVTD-KENTV--S------------EGNN-------------WKF-QVE-K-
-------TRCSTFF-SF-SSEQS--SGPNTLALILGPVS--AA-LLVLATAFAVFKYRQI
K--RSDLVSV----GSYRTNISMSDFE-NAKEYGANDNVCMRQ---SQETQLGG-DEF--
-VTTTA--------SIESTAETKKAKR---------------------------------
-GSKEDA-DLAYSASLLTPSTVTQSSVGDSTAPAEAPPLWGGSM-

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWPLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KVEG
ELGGSVTIKCPL-----PEMHVRIYLCREMAG-SGTCGTVVST---TNFIKAEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGMNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEKQP-----MPET--------PKWF--------HL-PY---L
FQMPAYASSSKFVTRV---------TTPA--QRGKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVAGDKPPTFLPS-----
----TTA-SKVSALEGLLKPQTPSYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILLPTILGLFLLALL----GLVVKRAVERRK-A-LS-RRARRLAVRMRALQ-
S---SQRPR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------TG-E----APVPGPGV-----P--------------
-----------------------LPPAPL--QVSESPWLHAP--SLKTSCEY------VS
LYHQPATMMEDSD--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDQDA-----PAKPR---------
-----------------------------------------------------------E
QKVSHQRTRWKI-LLLILCLLHGSSMTPPHRRPHSRGL----------------QVGSP-
--PSRTHLCT-----MEAHTTSTP----PCCW-R-NSL--------TGANALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 343)

PRLVSG
EAGGAVTIHCHYAP-SSVNRHQRKYWCRLGPP-LWICSTIVST---NHYTHRDYRGRVAL
TDL-----PQSSLFTVKLSRLSLNDTGLYRCGIGDRND-M--LFF---------RMNLIV
SAGPSN--TTYAA-SPASGE-----LITASPGIASTA-ANRWTPGA--------------
----------------------------T--SIPEGQGSEWDRT----------------
-----------------------------------------------------AP-----
----TTGIRRTTALP---------------------------------------------
------------------------------------NGRQTPRT-ARTTVPRTHSREEG-
S----IKTA-V------PTPES-------------------PASKSRSMFSTTPGVRLWG
TRN----SETQTTSAS---TS---EGWGKGPTPEADGPRGET--E---------------
--------VSASPEALRKITGTTGPSVL----ISE----HVTWEALHEA-----------
---REDS-------------KQQARYSVEESSPAPSAWTLNTT-----------------
------------HV-PVPS-G---STDGNLE----------------------NTD----
-----GES-SPPTPSQLSSGG------------PRW--AP--------------------
-------GQGSSM--KSALTGGE--SNSWIL----TPVS--TVLALVLLAALVLLKRRPW
RERA----SQEAERPPRITLIQMTHF------LPD-KLPAVGK-------NLQQ-GDL--
-PSVQASL-----TVLEKDPGP--------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TVKPGEQKEVVRRG
REV-DYS------------------------------------------RLIAGT-LPQS
HVTS-RRAGWKMPLFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRA-----MGTLTPSSP----LCWR-EESSF--------AAPNSLKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 345)

SRLVSG
EPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NQYTHHRYRDRVAL
TDF-----PQRGFFVVRLSQLSPDDIGCYLCGIGSENN-M--LFL---------SMNLTI
SAGPAS--TLP-TATPAAGE-----LTMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSKTTASA---------------------------------------------
------------------------------------EGRRTPGA-TRPAAPGTGSWAEG-
S----VKAP-A------PIP-------------------ESPPSKSRSMSNITEGVWE-G
TRS----SV--TNRAR---AS---KDRREMTTTKADRPREDI--EG--------------
--------VRIALDAAKKVLGTIGPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSQGSIGETTPAAGMWTLGTPAADV------------W
I-LGTPAADVWTSM-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWG--PP--------------------
-------GKESSV--KRTFPDDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLW
R-RRT---SQEAE---RVTLIQMTHFL-EVNPQPD-QLPHVER-------KMLQ-DDS--
-LPAGASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MGLWLWSLYFLPL--------SGALKILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

HVEG
EPGGSVIIECPL-----PKTKARIYLCRETSS-SGICATVVSS---TNFIKKEYTGRVTL
QLC-----PDKDLFLVEVTELTESDSGAYACGAGTNTDKG--RTQ---------KVTLNV
HSE----------YEPFWEEEL-----MPEP--------PKWF--------HM-PP---W
FQAPTRTSSSKFISKV---------TTQA--QRTEAPPAHHPSPTTL--IIHH--PRVSR
AS----------------------------------------SVAATKPPTLPPS-----
----TTA-SKISARERLLGPQTASYNHHTR-LHRQRAPNRG--------SQAGRE-GP--
-----GFHILIPTTLGLFLLVLL----GLLVKRAVQRRK-A-LS-RRVRRLALRMRALE-
A---SQRPL-A------QRPG----------------TSRRLRS-----QSNVYSACPRR
ARP----ADAAG------------DG-E----APVPGPGT-----S--------------
-----------------------APSAPP--QESEAPWLHAS--SLKTSCEY------VS
FYHRPNAKMEDTD--SDDYINVPAL-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------LGLWPL-IDTL--------SAALKILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

HVEG
VLGGSVVIECPL-----PKTKVRLYLCRETGR-TGMCATVVSS---TSYTKKEYMGRVTL
QLC-----PDKNLFLVEVTELAESDSGDYACGAGTNTDRG--KTQ---------KVTLNV
HSE----------YEPFWEEEPI----MPEP--------PKWFYKFLHL--HV-PP---W
FQAPTHASSYKFTSKV---------TTQA--QRTEAPPAHRPSPTTL--TIRH--PRVSR
AS----------------------------------------SAAATKPPTLPPS-----
----TAA-SKISARERLLGPRTAGYGHHTR-LHRQRVGQT---------PGKRRA-KP--
-----GFHILIPTTLAFSCW-SF----GLLVKRPFKG---K-GE-RRVRRLALRMRALE-
A---SQRPS-G------RGRA----------------GGVRVG------------PRPSP
HRG----L-------------------D----VRVPGPGTSA--PP--------------
-----------------------APPAPP--QDSEAPWLHAS--SLKTSCEY------VS
FYHRPDAKTEDSD--SDDYINIPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDQGA-----PAKPSEQKQLTCQD
RQFPGPAFRVEL---------PSYWSKLRVHSQSAEPWTPDHSLQLLTSLPLASCL---W
LQVPSLRTRWEI-LL-LLCLLHGSSMTPPHRRSHSRWL----------------QAGSP-
--QFRTHLYT-----VEAHTAPTP----LCCW-K-NSL--------SGTNALR

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVTG
NTGGAVTIHCHYAP-SSVNRHQRKYWCRLGSP-LWICHTVVST---NQYTHPDYRGRAAL
TDV-----PQSGLFVVRLLRLSLGDVGLYRCGIGDRND-M--LFF---------SVNLTV
SAGPSN--TTYAA-APASGE-----PPTASPGAASSA-GNGWTSGV--------------
----------------------------T--HILEGSGSEWDRT----------------
-----------------------------------------------------AP-----
----TTGTSKTTSSA---------------------------------------------
------------------------------------NGRQTLRT-ARTMVSGTGSREEG-
S----IKAA-V------PTPEG-------------------PSPKSRSMSSTTQGVWLWS
TRN----SV--TSSVT---TS---EGRRQGTTPETDGPRDET--D---------------
--------VRVSPEAPRKTTGTTRPSAL----ISE----HVTWETLQDK-----------
---TEVS-------------KQQMLHSLEELSPAPSAQTLNAT-----------------
------------CL-EVAS-EEGRSIDGSLE----------------------NTT----
-----EES-SPPTPSQLSAAG------------PVW--VS--------------------
-------GKGPSM--KSALMEGE--SHTGIL----TPVS--TVLALLLIAALILLKRSLG
RQRT----SQKKERVPRITLIQMTHF------LPD-KLPDEGK-------NFQQ-SDL--
-LPPQASL-----TVLENDPRP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTLL-----------------LLACLLAVFPAI--------SM

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

KSPIFGPQEVNS
LEGNSVSIKCYYPA-TSVNRHSRKYWCRQDS--RGRCVTLISS---GGFISQNYTDRANL
TNF-----PEDNMFAVDITHLIQTDTGKYKCGVGIN-NRG--LSF---------DVSLKV

ENSGT00530000063436_0_Linker_1_2 (361, 383)

GKG--------------HEFPA

PF07686 // ENSGT00530000063436_0_Domain_2 (383, 533)

DTQVYT-DLSRKV--TI-------------------SC
PFSAENSQ-KKSLCKKT-EQNCVLVIDST--GYVS------PSYTDRTQLKMQ-GTSKLV
FSVTIGRLRPEDAGAYECRAGEE---------------------SRDVNLQVLK--PEPE
LLYG-----------DLRGSVSFDCTLGPE-MAEVPKF------------LCRVNTKEAC
DLVINSQGKKAPGFEGRILLDLMD-KEGSFSVLITGLRKED-AG---RYLCGANPNGQLV
EGWPLQAWQ-LFVNE

PF07686 // ENSGT00530000063436_0_Domain_4 (676, 799)

ETSIPLSPSVVKGVPGGSVTVLCPYNPKE-----SDHLKYWCHWE
ETQ-NGRCPLLVDSQGLVNQK---YQGR---LALHQEPGNGT--YSVILNQLTAQDAGFY
WCQTNGDSRWRSTVELKV

ENSGT00530000063436_0_Linker_4_5 (799, 804)

VE--G

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

EPSLKV---PENVTAWIGK--TVNISCHFPCKFYS--
-YEKYWCKWSNGI--------CQALPSQDEGSSQAFSNCNQKSQLISLILDSVTKADEGW
YWCGVKQGHHYGETVAIYVSVEEM-TK---------------------ESQDFSQA-DAI
PNEVVVDPNVR------ES----------------------GNKAVQDPRLVVEQ-----
DSEDPADESRV-----SSAEGQG--GRSPVLVSTLVPLA--LV-LALGAMAVGVLRARHR
--KNVXXXXX----XXXXXXXXXXXXX-XXXXXXXXXXXXXXXX--XXXXXXXXXXXX--
-XXXXXXX--------XXXXXXXXXXX---------------------------------
-SSKEEA-DMAYTAFLLQANNIAA-NVQDGP--HDA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MKLL-----------------FLTCLLVVFPVV--------SMKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 335)

PQEVSS
VEGGSASITCYYPA-TSVNRHTRKYWCRQGA--KGRCTTLISS---EGYISKDYEGRAKL
TNF-----PENSTFVVNIGHLTRNDSGRYKCGLG

ENSGT00530000063436_0_Linker_1_2 (335, 390)

IS-SRG--LNF---------DVSLEV
GQG--------------PGAGDDTEVYIA

PF07686 // ENSGT00530000063436_0_Domain_2 (390, 533)

DLGRTV--TI-------------------NC
PFKSENSEKRKSVCKKT-GQLCVLVIDSN--GYVN------PNYSNRAVIDID-GTSQVT
FSFVIKRIRLSDAGIYVCQAGDD-SSND----------------KHNVDLQV

ENSGT00530000063436_0_Linker_2_3 (533, 557)

LK--PEPE
LLYG-----------D

PF07686 // ENSGT00530000063436_0_Domain_3 (557, 666)

LRGSVTFGCALGSE-VASVSKF------------LCRMSNEEDC
DVVINTLGKKSKDFEGRILLTPRD--QGFFSVHITGLRKED-AG---YYLCGAHSDGQPH
EGSPT

ENSGT00530000063436_0_Linker_3_4 (666, 681)

QIWQ-LFVNEETTMP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QSPSVVKGVVGGSVAVLCPYNPKE-----ADSLKYWCRWE
NTP-NGRCQQLVESEGLVNEQ---YEGR---LALYKEPGNGT--YTVLLNQLTNEDAGFY
WCLTSGDTRWRSTVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

IVEG--EPSLKA--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 912)

-PKNVTAWVGE--TFKLPCHFPCKYYS--
-YEKYWCKWSNKG--------CKTLPTQDDGPSQAFVNCDQKSQIISLTLNPVAKEDEGW
YWCGVKEGHRYGETMAVYVAVEER-VRGSQDV--S-------------QV----R---AA
PGEEEVESSVR------KTEN----------------------KVIQDPRLSVEDRP-VK
DTGDPAGESRASAD-TDSSAEQG--RSSKVLVSTLVPLG--LV-LALGAVVVGVLRARHR
--KNVDRISV----RSYRTDISMSDFE-NSREFGANDNMGASQV--TQETSLGGKDEF--
-SAT--------TGNTMETEEPKKPKR---------------------------------
-SSKEEA-DMAYTAFLLQTNNMAA-DVQGAP--SEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLRLWLLYFLPA--------

PF07686 // ENSGT00530000063436_0_Domain_1 (227, 361)

AGALGALPEVKLEA
ELGGSVTIKCPL-----PEALGGMYLCRQMAD-SKPCATVVS----TYYTKDEFKGRVTL
LAH-----SKKHLFLVKMTELTEKDSGVYACGVGLNTDRD--KTQ---------KVTLTV
HTE----------YEPFWDEDP-----MPRP--------PERF--------QL-PR---R
FQMPSPASSFQSTSKA---------TPQA--QNIKAPAAHRPSPTAP--ITHQ--LRVSR
AS----------------------------------------PGAVARPPTLPPS-----
----AA---KTPAKKVLLRPWTVAYNHHTK-MHRQRALGSG--------SLSETG-DQ--
-----GLHILIPVCLAFLLLALL----GLVVKRVVQRRR-A-FY-RRIRRQAVRMRSPG-
S---SQRSR----------------------------ASQRPRS-----QNNVYSACPRR
ARE----PDAPG------------GP-E----SQLDTPGV-----S--------------
-----------------------ASPAQP--QVSETPWLHAT--APKTSCEY------VS
ICHQPAANTEDPD--SDDYVNIPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLS-----------------LLVSLLAVFPVV--------STKSPVFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 336)

PEEVNA
VEGSSVSIKCYYPA-TSVNRHTRKYWCRQGA--SGSCITLISS---GGYISKDYVGRSNL
TNF-----PEIGAFEVNISPVSREDSGHYKCGLGI

ENSGT00530000063436_0_Linker_1_2 (336, 388)

N-TRG--LNF---------DVGLEV
VKD--------------PRLLNNTEVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 533)

TMDLGRTV--TI-------------------TC
PFRSENGGKKKSLCKKT-GQSCELVIDSD--KNEN------PSFAGRVRLVIQ-GTDQEV
FSVVINQLRNRDAGMYVCQAGED-PSGD----------------TKNIHLQV

ENSGT00530000063436_0_Linker_2_3 (533, 539)

LE--PE

PF07686 // ENSGT00530000063436_0_Domain_3 (539, 659)

PE
LVYG-----------QLRGSVTLDCALGPE-MANVQKF------------LCRVNKDKSC
DVIINTLGKRDPAFEGRILLTPRDPSDGHFSVLITGLQTGD-EG---EYLCGAHPDGV

ENSGT00530000063436_0_Linker_3_4 (659, 681)

PQ
EGWPLQAWQ-LFVNQETPIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QTPSLVKGVTGGSVAVLCPYDPKE-----SQSFKYWCLWK
GEK-NGRCPLLVESQGLVQEE---FEGR---LALYEEPGNGF--YTVILNQLTTQDAGFY
WCLTNGDTRWRTMVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVDG--EPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 918)

-PKNTTVVLGQ--TLKLDCHYPCKFYA--
-YKKYWCKWSNQG--------CRALPSQDEGPSQAIVGCDQNNQKVSLTLQSVTKADEGW
YWCGVKQNQTFGETVAVYVAVEEA-ARGSGVP--N-------------PVNP-VIA-NSA
PEEEVVKPRGR------EVENEVI-----------------ENKAVPNPRLFAEERV-VE
DSGNQASGSRASVD-DSSSQGQS--RSSKVLLSTLVPLG--LV-LALGTVAVWVARARHR
--KNVDRISI----RSYRTDISMSDFE-SSRDFGANDNMGASSV--TQETVLEGKVEA--
-MANAEST--------TDTEEPKRAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSSIAA-QAQDGP--KDT---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MSRL-----------------FLACLLAIFPVV--------SMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 344)

PIFGPEEVSS
VEGRSVSIKCYYPP-TSVNRHTRKYWCRQGA--QGRCTTLISS---EGYVSDDYVGRANL
TNF-----PESGTFVVDISRLTHKDSGRYKCGLGIS-SRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 380)

NF---------DVSLEV
SQD--------------PA

PF07686 // ENSGT00530000063436_0_Domain_2 (380, 503)

QASHAHVYTVDLGRTV--TI-------------------NC
PFTRANSQKRKSLCKKT-IQDCFQVIDST--GYVS------NSYKDRTHISIL-GTNTLV
FSVVINRVKLSDAGMYVCQAGD

ENSGT00530000063436_0_Linker_2_3 (503, 559)

D-AKAD----------------KINIDLQVLE--PEPE
LVYG-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 656)

SSVTFDCSLGPE-VAHVPKF------------LCQKKNGGAC
NVVINTLGKKAQDFQGRIVSVPKD--NGVFSVHITSLRKED-AG---RYVCGAQP

ENSGT00530000063436_0_Linker_3_4 (656, 681)

EGEPQ
DGWPVQAWQ-LFVNEETAIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

ASPSVVKGVRGGSVTVSCPYNPKD-----ANSAKYWCHWE
EAQ-NGRCPRLVESRGLMKEQ---YEGR---LVLLTEPGNGT--YTVILNQLTDQDAGFY
WCVTDGDTRWISTVELK

ENSGT00530000063436_0_Linker_4_5 (798, 812)

VVQG--EPSLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 912)

-PKNVTAWLGE--PLKLSCHFPCKFYS--
-FEKYWCKWSNRG--------CSALPTQNDGPSQAFVSCDQNSQVVSLNLDTVTKEDEGW
YWCGVKEGPRYGETAAVYVAVESR-VKGSQGA--K-------------QV----KA-APA
--GAAIQSRAG------EIQN----------------------KALLDPSFFA-KES-VK
D---AAGGPGAPAD-PGRPTGYS--GSSKALVSTLVPLA--LV-LVAGVVAIGVVRARHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFEGRDNMGASPE--AQETSLGGKDEF--
-ATT--------TEDTVESKEPKKAKR---------------------------------
-SSKEEA-DEAFTTFLLQAKNLASAATQNGP--TEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWALYFLPV--------VGAPKVLPEVKMEG

PF07686 // ENSGT00530000063436_0_Domain_1 (241, 360)

MLGGSITIECPLP-----ETHVRIYLCRTIDE-SGRCTTVVSS---NKYVREEFKHRVTL
EQC-----PDRNLFLVVMTELTKNDSGIYACGVGGNTDRG--KTQ---------QITLTV
HS----------VYEPSWEEEP-----MPEP--------PAWFNRFLQM--HL-PP---W
FQMPAHASSLKFMSKV---------TTPA--QRTKSPRAHQASPKPS--VTHR--PRVFR
AS----------------------------------------SVATAEPTIFLPA-----
----ITT-SKTSAQKGLLRLQTVSYNHQTR-LHRQRASNQGP------GAASGME-DQ--
-----GVFVLIPTILGLILLALL----GLLAKRIIQRRKEA-LS-RRVRRLAVRMRTLD-
A---SQRAL-S------RRPR----------------VSRRPRT-----PSNIYSACPRR
PRG----VDAAGGRA----AS---PP-V--------P-GA-----P--------------
-----------------------AASAQP--QVPEIPWLHVP--SLKIDCEY------VS
FCHQPAAKVEDTD--SDDYVNVACLTHLSSCAPEPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDQAK-----A--------PPPRT
GSPLALPFRWDHPL----------WSKLRSYSQSGQPWTPCHSLWLLICLPQASCL---W
LQVSGQRTRWKL-LLLILCLLHGSSMTPPHRRPHSRGL----------------QAGSP-
--PSRIHLCT-----METHTDYTP----PCCW-K-NSL--------TDANALRG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 343)

PRLVSG
KIGGAVTIHCHYAP-SSVNRHQRKYWCRPGPP-LWICYTIVST---NHYTHHDYKGRVTL
TDF-----PQSSLFMVKLSQLSPNDTGLYRCGIGDRND-M--LFF---------EMNLIV
SAGPSN--TTYAA-ALTSAE-----LITASPGRAE-A-TNRWTLGV--------------
----------------------------T--QTLEGQGSERNRT----------------
-----------------------------------------------------DL-----
----TTRISKTIASA---------------------------------------------
------------------------------------NGRQTPRA-ARTMVPGTSSREEG-
S----IKAI-V------PTPQS-------------------PDSKSKSMFSTTQGVLIWG
TRN----SA--TTSAS---TS---EGEKKGTTPAADGPQEET--E---------------
--------VSMSPEALRKTTGANRPSVL----ISE----NVTLETLQEA-----------
---MEAS-------------NQRTLDSAEESSPAPNAWTENTT-----------------
------------HM-QMTS-G---SIDWSLE----------------------NTG----
-----GES-RPAAPSQLSPDG------------PMR--TP--------------------
-------GNESSM--KSAFTEGE--SNSWIL----TPVS--TVLVLVLLASLVLLKRRLR
RERT----SKEAERPPRITLIQVTHL------LPD-KLPNVGK-------NLHQ-GDL--
-PPAQGSL-----FVLED------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MCLWLWLLCFLPV--------SGTLKVLPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LDA
EWGGSIIIKCPLPH---PQTGVRMYLCREMTD-PRICATVVSN----SFIRKEYEGRAAL
LPW-----PDQKHFLVELRRLTESDNGVYACGVGGHTDRG--KTQ---------RITLKV
HPEY----------DPFWEEEP-----PPEL--------PQWFHRFLQE--QI-PS---R
LHEVEHVTSSESISEV---------TTPA--PRTKAPPAHQPSSTVP--VTHH--PRVSR
TS----------------------------------------SMTVAKSPALLPA-----
----PTA-SKTSAQPA-LRPLAASYSHRIS-LQGQRTPHHN--------PQYERE-DQGL
HIPVLEFHILIPAFLGFLLLVLL----GLMVKRAVQRRK-A-FS-RRVGRVAMRIRGRE-
A---SRQFP-T------QRPG----------------APQRPRS-----QNNVYSACPRR
API----PDRVG------------PT-E----TPLLSTPA-----S--------------
-----------------------APPAPP--QVLEAPWPHTP--PLKTSCEY------VM
LGHQPAVNVEDSD--PDDYINIPGPCHLPSCPPRPRSSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRVLPEI

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KLEG
VLGGSIVIECPLP-----ETPVRLYLCRTMAL-SGTCTTVVSN---KNFVLEEFKHRVTL
ELC-----PDRKLFLVEVTELTERDSGVYACGVGMNTNRG--KTQ---------QVTLTV
HS----------DYRPFWEEDP-----MPEP--------PAWFNRFLQM--HMPPP---W
FKTPAYASPFEFIPKE---------TSPS--QRTKAPPAHHTSPTTS--VTHH--PRVSK
AS----------------------------------------SVATAEPTTLLPP-----
----TTA-LKTSARETLLRPQTASYNHQTR-LHRQRAFNQRL------GPVSRMR-EQ--
-----GFHVLIPAALGFILLALL----VLLARRVFQRRK-A-LS-RRVRRLAVRMRALE-
A---SQ------------RPR----------------ILQRART-----QNNVYSACPRR
PRG----ADAAGGQQ----AG---QG-A----APPLGSAA-----L--------------
-----------------------ATSPPP--QVTETPWLHAP--SLRIGCEY------VR
FYHQPAAEMGDTN--SDDYVNVPCRTLRSNCPPGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGEA-----TLKLREQKVANR--
------------------------------------------------------------
R------AGWKMPFFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRT-----LGTLRPSSS----LCWR-EESSF--------AAPNALKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 338)

SRLVSG
EPGGAVTIRCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---SHYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENA-M--LFL---------SMNLTI
SAGPSS--TLP-TATPAVGE-----LTMRSYGTAFPV-ANRWIPGT--------------
----------------------------T--QT-SGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSMTTASA---------------------------------------------
------------------------------------EGSQTPGA-TRLAAPGTGSWAEG-
S----VKVP-A------PIP-------------------ESPAAKSRSMSDTTEGVWG-G
TRS----SV--TNGVR---AS---KDRREMTTTKADRPKEDT--EG--------------
--------VRITLDVAKNVLGTIRPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSLGYVGETTPAVGLWTLGT------------------
-----PAAGVWTSI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQAPAVG------------PWR--PP--------------------
-------GKESSV--KSAFPEEE--SSSRTL----APVS--TMLALFMLMALVLLQRKLR
R-RRI---SQEAE---RVTLIQMTHFL-EVNLQPD-QLPHVER-------KMLQ-DDS--
-LPAEASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVNS
VEGNSVSITCYYPP-SSVNRHTRKYWCRRGA--SGRCVTLISS---EGYVSNNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGLYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PGLLNDTKV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDLGRTV--TI-------------------NC
PFKTENAPKRKSLYKQI-GLSPVLVIDSS--GYVN------PSYRGRIRLDIQ-GTGQLM
FSVVINRLRLSDAGQYFCQAGDD-SNSN----------------KKNADLQVLK--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRESSGENC
DVVVNTLGKRAPAFEGRILLNPQD-KDGSFSVVITGLRKED-AG---RYLCGAHSDGQLQ
EGSPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVSVLCPYNPKE-----SKSIKYWCLWE
GAQ-NGRCPLLVESQGRVQEQ---YEGR---LSLLEEPGNGT--FTVILNQLTSQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVSCHFPCKFSS--
-YEKYWCKWNNTG--------CQALPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEESKAAGSHDV--S-------------LAKA-----DTA
PDEKVLDSGAR--------E---I-----------------ENKAIQDPRLFAEEKA-VA
DTGDQAGGSRASVD-SGSSEEQG--GSSRVLVSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQSSTVAA-EAQD-----------SPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KVEG
ELGGSVTIKCPL-----PEMHVRMYLCREMVE-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVGDEPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------ER-P--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHMRMYLCREMVG-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MSET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKFPPVHHSSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVGDEPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWFHAP--SLKSSC--EY----VS
LYHQPAAKMEDNN--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGES-----PAKPGEQ-------
------------------------------------------------------------
-KLPLW-----LEGPSPPCAP-GSALAPPHGRPRLRWL----------------WDGSL-
--PSGPTLWA-----TETLPVFSP----LCWR-E-ESI--------PA

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ANALRGPRLVSG
EPGGAVTIRCHYPP-LPINSHQRKYWCRLRPL-TWVCHTIVST---NRYTHLRYRGRVAL
TDF-----PQRGLFVVRLSQLSPEDVGHYRCGIGNANN-M--LFF---------SMNLTI
SAGLSR--AVP-TATVAAGE-----LITGSFVTVSS-AANRRTPGT--------------
----------------------------M--QTIERQGTGWDRV----------------
-----------------------------------------------------AL-----
----TLGTSKTTASA---------------------------------------------
------------------------------------KGRETPGA-TGVVAPGTGSQLEG-
S----IWAT-I------PTPQS-------------------PASAIRGVSNTTEGDRVWS
TRS----LE--ANRTR---AS---ERERET-TTGTDRQREET--ER--------------
--------VRTVPDTAEKVMATIRPSTL----VSD----KWMWETHQEE-----------
---MSVS-------------KPQALGSVEGTPPVAVVWTLEPT-----------------
------------SI-EMAS-AEG-SSEGDLD----------------------TPA----
-----GDSGPQVTSSQALAAR------------PFR--PL--------------------
-------GKDSQV--KRTPGPGL--NIPKGIKFSAQ-AH--SVLCV--------------
---CA---AQETERSSGVTLIQMTQFP-ELSLQPD-QLPQVER-------KVLQ-DDS--
-PPLRASL-----SIPERDPGPQ-------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLF-----------------VLSCLLAVFPAV--------SL

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

KSPIFGPEDISR
EEGSSASIKCFYPA-TSVNKHSRKYWCRQGP--TGPCVTLLSS---PTYVSKDYQGRAKL
TDF-----PESNVFVVDISNLSKDDSGSYKCGVGTN-NRG--LSF---------DVNLQV
SQA----------------LPDDTDVYKADLDETV--TA-------------------VC
PFTRSNSFKKKSVCKKT-DQECIPVIDSE--NYKN------PDFGNRISLVIL-GTSAKH
FNFVINQLQPTDTGIYVCKTGDS-SNVD----------------IKDFYLQVPKPKPEPE
LAYG-----------DLRGSVTINCDLDPT-VANEAKF------------LCRKNNEKAC
DVVVNTMGVQDQAFEGRILLTPKD--KGSFSVMINGLKKED-AG---HYLCGASSNGEPQ
EGKPTQAWQ-LFVNE

PF07686 // ENSGT00530000063436_0_Domain_4 (676, 799)

ETTVRLGSPVIKGVEGGSVALRCPYNPKE-----RDSVKYLCRWE
DGN---NCPVLVRSNGLPQEQIKAYGGR---IALNEEPGSGF--YTVILNKLTTKDAGFY
WCRINGDKRLTSVVELKV

ENSGT00530000063436_0_Linker_4_5 (799, 804)

VEG--

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

KPTLKV---PETVTAFEGN--TTKIPCHVPCKFYS--
-YEKYWCKWTNKG--------CKALPTQDPGFSQPSVNCNLES-FMELILSPVIEQDEGW
YWCGVKNGLRYEETMAVCVEVKKW-VKXXXXX--X-------------XXXX-----XXX
XXXXXXXSDVR------ET----------------------ENKAIQDASLVVEDRA-ME
GMKNPVDASSSSTD-TGSSAGQG--GSTTVLVSTLVPLA--LV-LALGGVALGVARARHR
--RNVDRISI----KSYKTDISMSDFD-NPREFGANDNPGASPF--SQETPVDGNNEF--
-VITTEAA--------METKETKESKR---------------------------------
-SSKEEA-EMAYTNFVLQSNIAAM---SDRP--SEV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MCLWLWLLYFLPV--------SGALKVLPEVQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 360)

LNA
EWGGSITIKCPLP-----QIHTRMYLCRQMTD-PQICTTVVSS----SFVKKDYKARVTL
TPW-----LNKKLFLVEMTQLTESDNGVYACGVGTNTDLG--KTQ---------KIILNV
HDEY----------EPFWEDEP-----TTEP--------PPWFHRFLQE--HI-PS---W
LHEVGHAS-----SEV---------TTSA--PRTE-APVHQPSSTIP--ATHY--PRVPR
TS----------------------------------------SVTAAKSPTLLPT-----
----TTA-SKTSAQQA-LGPLGASYSHHTK-LHGQRTLHHS--------PQYERE-DQGL
HIPVLEFHILIPTFLGFLLLVLL----GLVVKRAILRRK-A-FS-RRMGRVAMRIRGQE-
A---SRRFP-A------QRRG----------------ALQRPRS-----QNNVYSACPRR
APP----PDQEG------------SA-E----ASLLSAPA-----S--------------
-----------------------APPDP--SQVLEAPWCHTP--PLKTSCEY------VT
LCHQPAVNVEDTG--SDDYINIPGPRHLPSCPPGHRPSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWALYFLPV--------VGAPKVLPEVKMEG
ML

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GGSITIECPLP-----ETYVRIYLCRTIDE-SGRCTTVVSS---SKFVREEFKHRVTL
EQY-----PDRNLFLVEMTALTKNDSGVYACGVGLNTDRG--KTQ---------QITLTV
HS----------VYEPSWEEEP-----MPEP--------PAWFNRFLQM--HM-PP---W
FQMPPHASSLEFLSKV---------TTPA--QRTESPQAHQASPNPS--VTHR--PRVSR
AS----------------------------------------SVATAEPTIFLQS-----
----ITT-SKTSAQEGLLRLQTASYNQQTR-LHRQRGSNQDP------GAASGME-DQ--
-----GVFVLIPTILGLILLALL----GLLAKRIVRRRKEA-LS-RRVRRLAVRMPTVD-
A---SQRAR-S------QRPR----------------VSRRPRT-----PSNIYSACPRR
PRG----VDAAGGRR----AG---LG-V--------RAGV-----G--------------
-----------------------GEDQEP--EVPEIPWLPVP--SLKIDCEY------VS
FCHPTAAQVEDTD--SNDYVNVACLTHLSSCAPGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MNLWLWSLCFLPV--------SGALKILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

TLDG
ALGGSVVIECPLA----GETEVRMYLCRQMVN-TGSCNTVVSN----NFVNDKYRHRVAL
MPC-----SDKNQFLVELSGLTESDSGVYACGLGKNTDRG--KTQ---------KVTLNV
HNE----------YEPFLE-EE-----PMSE-------PQKLLYEFLQQ--HM-PN---W
LQMLPQARDAEFIPKV---------ATPA--QRTEAPPVHHSGITTP--TTRQ--PRPST
AS----------------------------------------SAATAKLPTLLPS-----
----TTA-SDTSAQEGVLGPQEASYKHHSW-LHRQRAFTPGS--------QAGRE-DQ--
-----GFHILIPSVLGLLLLALL----GLVLRRAVQRRR-A-FS-RRIRRL---------
------------------------------------------------------------
---------------------------------------A-----V--------------
-----------------------RMRGLE--AVPETPWLYAP--SHKTSCEY------VT
ICHLPAAQREDPDSDEDDYINILSLTSLPSCPPGAIPWRQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLFF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIRCYYPP-TSVNRHTRKYWCRKGA--SGRCITLISS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSQDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTVDVGRTV--TI-------------------SC
PFKTENAPKMKALYKKI-GQVSVLVIDSR--NYVN------PDYKDRIRLHIS-GTGQLI
FTVVIDQLRLSDHGLYLCQAGDG-SSRD----------------EKNVDLQVLK--PEPE
LVYA-----------DLRASVTFHCALGPE-VANVAKF------------LCRVSSRETC
DVVINTLGKRDSAFEGRILLNPQD-QDGSFSVVITGLRKED-EG---HYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESAIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCHWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEERKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------Q---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSRALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETQEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGHQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDLWLWSLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

KVEG
ELGGSVTIKCPL-----PEMHVRMYLCREMVE-SGTCGTVVST---TNFIKVEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGRNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPPYASSSKVVTRV---------TTPA--QRTKVPPVHHSSPTTQ--ITHH--PRVSR
AS----------------------------------------SVVGDEPPTFLPS-----
----TTA-SKISALEKLLKPRTASYNHHTR-LHRQRTLDYG--------SRSGRE-GQ--
-----GFHILISTILGLFLLALL----GLVVKSAVERRK-A-LS-RRARRLAVMMRVLE-
S---SQRTR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------KG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWFHAP--SLKSSC--EY----VS
LYHQPAAKMEDSN--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MGVAPPTAFSLWIYLILPI--------SGALR-PPWIQ

PF07686 // ENSGT00530000063436_0_Domain_1 (238, 333)

LTG
ERAGSVTIRCPAK-----QSLGRKFLCRESHE-TEMCNTVVST---TQYVGKDYKNRVKL
TEV-----PQEDIFLVELGELTQSDTGLYACGTGLVTDRG--KTL---------WVSLSV
IRGRFS--C---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQTSVLVIDSR--NYVN------PNYKDRIRLRIP-GTGQLI
FTVVINRLRLSDHGLYLCQAGDG-SNHD----------------EKNADLQVLE--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGKRDSAFEGRILLNPQD-KDGSFSVVITGLRKED-EG---RYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 797)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWRTTVEL

ENSGT00530000063436_0_Linker_4_5 (797, 812)

KIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLNIPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEEKKVAGSRDV--S-------------PAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQNPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQS----------ST--MATEAQEGPQEA

------------------------------------MDGEA-----TVKPGEQKEVVRRG
REV-DYS------------------------------------------RLIAGT-LPQS
HVTS-RRAGWKMPLFLILCLLQGSSFALPQKRPHPRWL----------------WEGSL-
--PSRTHLRA-----MGTLRPSSP----LCWR-EESSF--------AAPNSLKG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 345)

SRLVSG
EPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NQYTHHRYRDRVAL
TDF-----PQRGLFVVRLSQLSPDDIGCYLCGIGSENN-M--LFL---------SMNLTI
SAGPAS--TLP-TATPAAGE-----LTMRSYGTASPV-ANRWTPGT--------------
----------------------------T--QT-LGQGTAWDTV----------------
-----------------------------------------------------AS-----
----TPGTSKTTASA---------------------------------------------
------------------------------------EGRRTPGA-TRPAAPGTGSWAEG-
S----VKAP-A------PIP-------------------ESPPSKSRSMSNTTEGVWE-G
TRS----SV--TNRAR---AS---KDRREMTTTKADRPREDI--EG--------------
--------VRIALDAAKKVLGTIGPPAL----VSE----TLAWEILPQA-----------
---TPVS-------------KQQSQGSIGETTPAAGMWTLGTPAADV------------W
I-LGTPAADVWTSM-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGPQATLSQTPAVG------------PWG--PP--------------------
-------GKESSV--KRTFPEDE--SSSRTL----APVS--TMLALFMLMALVLLQRKLW
R-RRT---SQEAE---RVTLIQMTHFL-EVNPQAD-QLPHVER-------KMLQ-DDS--
-LPAGASL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PEEVNS
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--RGGCITLISS---EGYVSSKYAGRANL
TNF-----PENGTFVVNIAQLSQDDSGRYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PGLLNDTKV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDLGRTV--TI-------------------DC
PFKTENAPKRKSLYKQI-GLYPVLVIDSS--GYVN------PNYTGRIRLDIQ-GTGQLV
FSVVINQLRLSDAGQYLCQAGDD-SNSN----------------KKNADLQ

ENSGT00530000063436_0_Linker_2_3 (532, 559)

VLK--PEPE
LVYE-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 664)

GSVTFHCALGLE-VANVAKF------------LCRQSSGENC
DVVVNTLGKRAPAFEGRILLNPQD-KDGSFSVVITGLRKED-AG---RYLCGAHSDGQLQ
EGS

ENSGT00530000063436_0_Linker_3_4 (664, 682)

PIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSIKYWCLWE
GAQ-NGRCPLLVESEGRVKEQ---YEGR---LSLLEEPGNGT--FTVILNQLTSQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLKVPCHFPCKFSS--
-YEKYWCKWNNTG--------CQALPSQDEGPSKAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAIYVAVEERKAAESRDV--S-------------LAKA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLVAEEKA-AA
DTRDQADGSRASVD-SGSSEEQG--GSSRALVSTLVPLG--LV-LAVGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLGGKDEF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMAYKDFLLQSSTVAA-EAQD-----------GPQEA

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------LM--------SGALKILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

ELEG
ALGGSVVIECPLL----EKGQVRMYLCRQMAN-PGICSTVVSS----NFIKDEYRHRVTL
MPC-----SDRKLFLVEMTGLTERDSGVYACGLGIHTDKG--KTL---------KVTLSV
HNE----------YEPFWEEEP-----MSES-------QSLWLHKLLQQ--QM-PS---W
LEMGALPFL---PSSA---------DATA--ERTEAPPVQRSAAATP--TAHR--PQTPG
AS----------------------------------------LAAAAKPPPLLPS-----
----TTA-SKASAQEGLLGPQEASYNHRTW-LHKQRDRSRGHLP---KAGRARAR-DL--
-----GFHILIPSALGLLLLALL----GLVLRRALQRRR-G-EQ-RRGTGPSARGAGAG-
A---GAGGP-G-----APRGW-------------GC----PVRL-----RGT-----AL-
P-------PALR--------------------------SQ-----G--------------
-----------------------CASLCP--QVPDAPWLPVP--SLKTSFEY------VT
ICHQPAARREDAE--SSDYINIPSLT----CPPGPRLWRQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------PTAV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 340)

PQDVSG
VVGNSVSVTCYYPA-TSVNRHSRKYWCRQGP--GSLCTTLVSS---NGYISKEYAGRANI
INF-----PENNTFTINIAQLTQNDTGSYKCGLGTS-NR

ENSGT00530000063436_0_Linker_1_2 (340, 388)

G--LYF---------EVSMEV
SQA--------------PEFPVDTHVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 532)

TKDLGRSV--TI-------------------AC
PFKKENAHSKKSLCKKI-GQTCELVIDST--EYVN------PKYKDRAILFMK-GTSQEL
FNVNITHLRHSDAGLYVCQAGEG-SSAD----------------RNNADLQVLD--PKPE
LVYR-----------DLRASVAFDCDLGRE-VADVAKY------------LCRMN-KETC
DVVINTLGRRDPAFEGRILLTHKD-DNGRFSVLITGLKKED-AG---QYLCGAHSSGLPQ
EGWPMQAWQ-LFVNEESTMPPSRS

PF07686 // ENSGT00530000063436_0_Domain_4 (685, 798)

VVKGITGGSVAIVCPYNPKE-----SSSLKYWCRWE
ADG-NGHCPVLVESQGVVDEQ---YEGR---LALFDQPGNGS--YTVILNQLTTQDAGSY
WCLTNGDSRWRSTVELQ

ENSGT00530000063436_0_Linker_4_5 (798, 813)

VAEGERKPNLEV--T

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 911)

PQNAIAVLGE--TLTLSCHYPCKYYS--
-HEKYWCKWSNKG--------CHILPSHNEAARQSSVSCDQDNQVISMTLNPVSKNDEGW
YWCGVRKGQDYGETTAIYVAVEER-TGGSRQV--S-------------PVDANAPA-NVA
PQEEVVDSGVS--------D---N-----------------ENKAIPNPSLLEEEGE-IN
SVGDQAQENRAAVD-AGSADEQK--GHSKILFSTLVPLG--LV-LAGGAVAVWVARVRHR
--KNVDRMSI----SSYRTDISMADFK-NSRDLGGNDNMGASPD--LQETALERKDEI--
-VTTTEIA--------TEPEESKKAKR---------------------------------
-SSKEEA-DLAYSAFLLQSSNIAA-QVHDGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------ALTCLLVVFPAV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQKLRR
VEGNSVSITCYYPP-TSVNRHTRKYWCRQGA--SGRCTTLISS---EGYVSDSYRGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQD--------------RGLLNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 533)

YTVDVGGTV--TI-------------------NC
PIKPENAEKVKSFHKMN-GQDPVLIIESG--KYVS------PIYGDRVKLVIP-GTGQLM
FMVIIHQLRPSDTGMYICKAGVG-SSAN----------------KKTVNLQV

ENSGT00530000063436_0_Linker_2_3 (533, 555)

LM--PEPS
LVYG----------

PF07686 // ENSGT00530000063436_0_Domain_3 (555, 661)

-DLRGSVTFNCALGPE-VANVPKF------------LCRMSDGKNC
DVLINTGGKRDQAFEGRILLSPKD-KSGSFSVPITGLRKED-AG---RYMCGAHPNDQLQ

ENSGT00530000063436_0_Linker_3_4 (661, 682)

ESWRIQAWE-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 791)

SPTVVKGVAGGSVAVVCPYNPKE-----SESIKYWCRWE
GAQ-NGHCPLLVESKGLVQDQ---YQGR---LALHQEPGNGT--YTVILNQLTSQDAGFY
WCLTNGDTHW

ENSGT00530000063436_0_Linker_4_5 (791, 812)

RTTVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 913)

-PGTVTAVVGE--TLKLPCHFPCKFYS--
-YEKYWCKWSNKG--------CQTLPSQDDGPSQAFVNCNQNSRLVSLTLNSVTKADEGW
YWCGVKQDHSYGETAAVYVAVEEKKVAGSRDA--S-------------PVKA-----DAA
PDEKMLESGVQ--------K---I-----------------GNRAVQDPRLFAEEKV-VA
DIGDQAGGSRISVD-SSSSEKQG--GSSRVLVSTLVPLG--LV-LALGAVAVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASTI--TQETSLGGKDGF--
-VATTEST--------TETKEPKKAKR---------------------------------
-SSKEEA-EMVYRDFLLQSSSVAA-EAQDGP--RE---------A

-----------------------------------------------IPYGEYKRSIRLG
------------------------------------------------------L-L---
VTSIVSRPGWKMTFFLTLCLLQGSSLTPPHRGPQFRWL----------------WEGSL-
--PSRTHIWP-----METLTPSSF----FCRR-EKSSF--------TTANGLK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
KPGGAVTIQCHYAP-LSVNRHQRKYWCRLGPP-KWICQTIVST---NYYTHHHYHGRVAL
EDF-----PQRGLFVVRLSKLSLDDVGCYHCGIGSKND-M--LFF---------SMNLTV
SAGPSS--TLS-TTTPAAEE-----PTMRLFRTVLPA-VNRWTPGT--------------
----------------------------T--QA-IGQGMEWDTT----------------
-----------------------------------------------------AP-----
----TPETSTTTTST---------------------------------------------
------------------------------------EGRQTPGT-RKTVSPGTGSWVEG-
P----IKAT-A------PIPQS-------------------PASKIRSMSNTTEGVWVWD
TRS----AV--TNRDG---IS---RDERGVTTVKADGPREET--ER--------------
--------DRIALDAATKVLGTIRPPVL----FSE----KLAWEVIQEV-----------
---TPIS-------------KQQFPSFTEGTIPAADMWTLGTI-----------------
------------SI-ETEY-VEG-GTTGDLD----------------------PAI----
-----GDSGPQARPSQSPAAG------------PSR--PS--------------------
-------GKGSSV--KSAFPEEE--NSSQIL----TPIS--IMLAVFMLVALVLLQRKLR
R-RRT---CE--L---RVTLIQMTHFL-DPNLQPD-QLPHVER-------KMLQ-DDS--
-PSAQPSL-----TIPEWEPRS--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------VSSTLYGPWFLTG
TV

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

GGSVTHQCFYSI-TPSNKHDRKYWCKRAS--NGVCYTIVST---TGYVSKGHVGRVSL
EDI-----PQNGTFMVTMTELESSDTGTYRCG

ENSGT00530000063436_0_Linker_1_2 (333, 379)

IGST-NRD--LYV---------SLNLTV
SEV--------------S

PF07686 // ENSGT00530000063436_0_Domain_2 (379, 525)

SPVFGPRQVYGLI-DGS-VTV-KCFY----------PPTKVN
----RH--DRKYWCRES-SRNCLTVVSSN--GYTS------PSYRGRASISDY--PEQGV
MVVNISQLVLSDRGTYQC---GVGLNGRGLSYKV--------SL

ENSGT00530000063436_0_Linker_2_3 (525, 558)

DISEGPNVPEE---AE
LFYV-----------EL

PF00047 // ENSGT00530000063436_0_Domain_3 (558, 653)

HGSVTMTCSFGAD-TVSMRKY------------LCKME-KNVC
NNIIDTHGKIDEDFTGRALLSNED-TDGAFSVMITQVNWED-AG---LYVCG

ENSGT00530000063436_0_Linker_3_4 (653, 676)

VGSYGEYG
E---TKELD-LHVYE

PF07686 // ENSGT00530000063436_0_Domain_4 (676, 799)

GSNVPQGKSTVTGVKGGSVTIECHYDPAK-----NYSLKYLCKWR
KNG----CSRIIENTGFVFDT---YEGR---VAMFDNPQNGT--FSVVLNQLRDNDKGYY
WCMTNDERERKSSKELKV

ENSGT00530000063436_0_Linker_4_5 (799, 804)

VE--G

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 922)

EPGLKG---KEDVLAEAGS--RVDLTCSYPCKYYS--
-YEKYWCKWSSDG--------CSPLSASDQSQPGVDVSCDTANKTLVLTFDSVTSADQGW
YWCGVKRNGHYGETLAVYLQVAG-GDAEKVA---E---LSPELLNLDTLRNAVAPSDAVA
P------SNAAA-PSNAV--A------------PG---------------------D-A-
-------AAPSNAA-AP-SSEQS--SGSNALTVALASSG--AA-VVVLGAAFAVFKYRQL
K--RSDLVSV----GSYRTNISMSDFE-SVKEYGANDNTCMKA---SQETQLGG-DEF--
-ITTTA--------SVESTAETKKAKR---------------------------------
-SSKEDA-DLAYSTYLLTSNAIAQGCAPGDSAA------------

------------------------------------MDQDS-----PTKPKEQKSPTSQD
RQSSGSALQ-VEFHSQ-------I----------TQPWTPCHSLWLLMCLPQVSS-----
-----RRTRWKI-LLLILCLLHGSSMTPPHRRLHSRGL----------------PAASP-
--PSRTHLCS-----LEADTASIP----PCCW-K-NSL--------TDANALR

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 340)

GPRLVSG
KIGGAVTIHCHYAP-SSVNRHQRKYWCRLGPP-LWICSTIVST---NHYTRHDYRGRVAL
TDF-----PQNGLFMVKLFQLSLNDTGLYHCGIGDRND-M--LFF---------RMNLIV
SAGPSN--TTSAA-APTSGE-----LITVSPGRAS-A-TNRWTLGV--------------
----------------------------T--QILEGQGSEWDRT----------------
-----------------------------------------------------DL-----
----TTRISKPAASG---------------------------------------------
------------------------------------NERQTPRT-ARTMVPGTSSSEEG-
S----IKAT-V------PTLES-------------------PASKSRSMFSTTQGVWIWG
TRN----SA--TASAS---TG---EGREKGTAPEADGPQEET--E---------------
--------VSTSPEALGKTTGANRLSVL----ISE----HVTWETLQEA-----------
---TEAS-------------KQQTLYSVEESSPAPNAWIVNAT-----------------
------------HT-QMAS-E---SLDWSLE----------------------NTG----
-----GES-RPPTPRQLSSEG------------PMW--TP--------------------
-------GKESSM--KSAFTEKE--SNSWIL----TPVS--TVLALVLLVSLVLFKRRLQ
RKTT----FQEAERPPRITLIQMTHF------LPD-KLPDLGK-------NLHQ-GDL--
-PPAQASL-----SVLEKD-----------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWLLYFLPV--------SGALRVLPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 360)

QLNV
EWGGSIIIECPLP-----QLHVRMYLCRQMAK-PGICSTVVSN----TFVKKEYERRVTL
TPC-----LDKKLFLVEMTQLTENDDGIYACGVGMKTDKG--KTQ---------KITLNV
HNE-----YP----EPFWEDEW-----TSER--------PRWLHRFLQH--QM--P---W
LHGSEHPSSSGVIAKV---------TTPT--PKTEAPPVHQPSSITS--VTQH--PRVYR
AF----------------------------------------SVSATKSPALLPA-----
----TTA-SKTSTQQA-IRPLEASYSHHTR-LHEQRTRHHG--------PHYGRE-DRGL
HIPIPEFHILIPTFLGFLLLVLL----GLVVKRAIQRRR-A-SS-RRAGRLAMRRRGRG-
A---SRPFP-T------QRRD----------------ASQRPRS-----QNNVYSACPRR
ARG----PDSLG------------PA-E----APLLNAPA-----S--------------
-----------------------ASPASP--QVLEAPWPHTP--SLKMSCEY------VS
LGYQPAVNLEDPD--SDDYINIPDPSHLPSYAPGPRSSCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------CRLAVSNQTLVLLSPE--------PVSS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 339)

SLHGSRFLAG
ALGGSITHQCFYSS-TPANKHQRKYWCKVAA--SGTCYTIISS----SFISSQYRGRVAL
GDT-----PQNGSFRVTMTGLSSSDSGTYRCGIGST-N

ENSGT00530000063436_0_Linker_1_2 (339, 383)

EG--LHV---------SLNLTV
LPA--------------STLPR

PF07686 // ENSGT00530000063436_0_Domain_2 (383, 506)

RPKFLSGTV-GGS-VTF-RCHH----------DPRGTY
--------EQQYLCRQV-GSRCSTVVSS---DYVS------PGYQGRAALSDH--PEAEN
FQVNISQLELGDAGTFQC---GVGV

ENSGT00530000063436_0_Linker_2_3 (506, 562)

NGRGLSHRV--------TLSVAEAPPVPEA---AE
LFYV-----------KLRSTW

PF07686 // ENSGT00530000063436_0_Domain_3 (562, 665)

TVSCSFGAD-TADQRRY------------LCKEE-KDGC
RNIVNSHQQIDPDFQGRVLLTFEE-PPGSFSVTMTQMDWED-TG---LYYCGAGEYGKEG
K---

ENSGT00530000063436_0_Linker_3_4 (665, 681)

SKELD-VFVYEDKNFP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 798)

QLKTTVTGKTGSSATFECLYDPLK-----KSSTRIWCKWR
IQG----CDKIIDNSGFVKYG---YEGR---VAMFENPENKT--VTIILNQLQAKDEGFY
WCMSNELKEQQSSTELK

ENSGT00530000063436_0_Linker_4_5 (798, 813)

VVK--GEPALNG---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 913)

TKEVEARVGS--RVDLTCSYPCQYYS--
-YEKYWCRWNDTG--------CALLPAQEQGLPGPAASCDTANRTAVLSFDPLQEDDAGW
YWCGVKHNGVLGETMAVELRVST-EGAGS----AE---ITPREESIK-FRDF-APE----
--KIKSDSKGQD-DSQLI--S------------NSRRKLL----DIPCTKQLFERTS-V-
-------NIREFSF-TS-SSDES--HGSNTVALVLGPLA--GL-ILIAVAAFAIVKYRQL
K--RSELVSV----GSYRTNISMSDFE-NVRDLSG-------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDGEA-----PAKPGEQ-------
------------------------------------------------------------
-KVTNPRAGWKMPFLLFLCLL---------------------------------------
----------------------------------------------QAANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
EPGGAVTIQCKYGP-LLISSHQRKYWCRLNPS-TGLCHTIVST---NRYTRPYYHGRVAL
EDF-----PKKGLFVVRLCQLSPEDVGYYRCGIGNNNN-L--LFF---------SMNLTV
SAGLSK--TIP-TATPAAGVAP--KLTTGPFGRASA-AANICMSGT--------------
----------------------------I--QTLEAQETEWNRV----------------
-----------------------------------------------------VL-----
----TLGTIETSATA---------------------------------------------
------------------------------------QERQTAGA-TVTVAPGTGGQVEV-
S----IWAT-V------PTTQS-------------------PASTIRGEFQTTGDVQVWG
STS----SE--AKKAT---AS---ERESGTATASASWQSEET--EW--------------
--------VRLASDTAGKVIGTTRPSTL----VSE----KWVWETPREK-----------
---VSVA-------------KPQALGSKKGPDPAAAVWTLELT-----------------
------------SM-EMAS-AEG-SSEGDLD----------------------NPA----
-----GDSGPPMTPSQALAAG------------PLR--PL--------------------
-------GEDSSV--KSSSQEEK--TLSRIL----TPLS--TVLCPLMLTTLVLLQRKLR
R-KSS---SQEVERSSRVTLIQMTRSG-AEPPAG---PAAPGG----------K-EDV--
-PR---------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MLLF-----------------VLTCLLAVFPAI--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 339)

PQEVSS
VEGNSVSIKCYYPP-TSVNRHTRKYWCRKGA--SGRCITLVSS---EGYVSSNYAGRANL
TNF-----PENGTFVVNIAQLSRDDSGHYKCGLGIN-S

ENSGT00530000063436_0_Linker_1_2 (339, 387)

RG--LSF---------DVSLEV
SQG--------------PELPNDTEV

PF07686 // ENSGT00530000063436_0_Domain_2 (387, 532)

YTVDVGRTV--TI-------------------KC
PFKTENAPKTKALYKKI-GQTSVLVIDSR--NYVN------PNYKDRIRLRIP-GTGQLI
FTVVIDRLRLSDHGLYLCQAGDG-SNHD----------------EKNADLQVLE--PEPE
LVYE-----------DLRGSVTFHCALGLE-VANVAKF------------LCRVNSRETC
DVVINTLGKRDSAFEGRILLNPQD-KDGSFSVVITGLRKED-EG---RYLCGAHSDGQLQ
EGWPIQAWQ-LFVNEESTIPR

PF07686 // ENSGT00530000063436_0_Domain_4 (682, 793)

SPTVVKGVAGGSVAVLCPYNPKE-----SKSLKYWCLWE
GAQ-NGRCPLLVESQGLVQEQ---YEGR---LSLLQEPGNGT--FTVILNQLTTQDAGFY
WCLTNGDTRWRT

ENSGT00530000063436_0_Linker_4_5 (793, 812)

TVEIKIIE--GEPNLKV--

PF07686 // ENSGT00530000063436_0_Domain_5 (812, 911)

-PGNVTAVLGE--TLNIPCHFPCKFSS--
-YEKYWCKWSNTG--------CQTLPSQDEGPSEAFVNCDENSRLVSLTLNPVTRADEGW
YWCGVKQGHFYGETAAVYVAVEE-KVAGSRDV--S-------------PAQA-----DAA
PDEKVLDSGVR--------E---I-----------------ENKAIQDPRLFAEEKV-VA
DTGDQAGGSRASVD-SSSSEEQG--GSSKALVSTLVPLG--LV-LALGAVVVGVARARHR
--KNVDRVSI----RSYRTDISMSDFE-NSREFGANDNMGASSI--TQETSLG---EF--
-VATPEST--------TETKEPKKAKR---------------------------------
-SSKDEA-EMAYKDFLLQS----------ST--MATEAQEGPQEA

------------------------------------MDAEA-----TVKSREQKETVRRG
AEA-DYC------------------------------------------RH-AGT-LPQS
HVIS-RRAGWKMPFFLILCLLQGSSFALPLKRPHLRWL----------------WEGSL-
--PSRTHLQA-----MGTFMPSSP----LCWQ-EESSF--------AVANALK

PF07686 // ENSGT00530000063436_0_Domain_1 (234, 360)

GPRLVSG
DPGGAVTIQCHYAP-SSVNRHQRKYWCRLGPP-RWICQTIVST---NHYIHHGYRDRVAL
TDF-----PQRGLFVVRLSQLSPEDIGCYLCGIGDENN-M--LFF---------SMNLTV
SAGPSS--TLP-TAIPAAGE-----LPTRSYGTASPA-ANRWNPGT--------------
----------------------------T--QT-LGQGTTWDTV----------------
-----------------------------------------------------AS-----
----APGTSMTRASA---------------------------------------------
------------------------------------EGRQTSGA-TRPAAPGTGSRAEA-
S----AKAL-A------PIPDS-------PASES-----------RS-MSNTTEGVWG-G
TRS----SM--TNKAR---AS---KDGREMTTTKVDRPREDT--ER--------------
--------VSIALEAAKKALGTISPPAP----VLE----TLAWEILPQCCLE--------
---TSVS-------------KQQSLGPIGETTPAAGVWTLGTT-----------------
------------SI-EAAS-GEG-SAAGDLD----------------------AAT----
-----GDRGSQATPSQALAVG------------PWR--PP--------------------
-------DKESSV--KSAFPEDE--SSSRTL----APVS--TLLVLFMLMALVLLQRKLG
R-RRT---SQEAE---RVTLIQMTRVL-EVNLQPD-QLPHMER-------KMLQ-GDS--
-PSAGTSL-----TAPERNPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------MPANIALV--------AGALRILPEVKMEG

PF07686 // ENSGT00530000063436_0_Domain_1 (241, 360)

MLGGSITIECPLP-----QMHVRLYLCREIAE-SGVCATVVSN---KNFVKEEYKHRVTL
KPC-----PDRKLFLVEVTELTKSDSGIYACGTGMNTDRG--KTQ---------QVTLSV
HS----------EYDLFWEEEP-----MPEP--------PSWFHKFLHM--PM-PP---W
FKMPPPPSSFEFIPKV---------VTPA--PRTEAPPAVHSSPPIP--ISHH--LRVSR
AS----------------------------------------SVAASKPPTLLPS-----
----TIA-SKTSAPEALPRPQTASYNYHTR-LHRQRAFHQD--------PVPGLE-DQ--
-----GFHILVPTTLALILLALL----GLLMKRVIQRRK-A-LS-KRARRAAVRMRALE-
A---SQRPP-P------HRPR----------------GSQPPRS-----QKHIYTACPRR
ARA----ADAEG---------------V----PPLPGSRP-----S--------------
-----------------------APPVAP--QASEVLWLHAP--SLKTSCDY------VS
CYREPAANAEDTD--SDDYVNIPYLTHLSSCPPGPRPWCQ--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----VMLF-----------------FLTCLLAVFPVV--------SMKSPIFGPQEVNR
LE

PF00047 // ENSGT00530000063436_0_Domain_1 (243, 333)

SASASIKCYYPA-TSVNRHSRKYWCQQGA--RGRCTTLISS---EGYVSKNYEGKANL
TNF-----PESNMFVVDIGHLTQNDSGRYRCG

ENSGT00530000063436_0_Linker_1_2 (333, 378)

LGMN-NQD--LFF---------DVRLKV
SPA--------------

PF07686 // ENSGT00530000063436_0_Domain_2 (378, 533)

LGLLNGTKVYTAELGRTV--TI-------------------SC
PFNSENSQEKKSVCRKT-DETCVLVIDSS--GYVS------PSYCDRVRLSIQ-GTSQLV
FNFVIDQLQLSDAGMYVCQAGDN-SRAD----------------KSNVDLQVLK--PEPK
LVYG-----------DLRGSVTFDCALSPK-VANLTKF------------VCRVNNGKGC
EVVINTLGKRAQAFEGRILLTLKD--KSSFRVHITGLKRED-AG---HYLCGAHSDGEPQ
EGWPTQAWQ-LFVNE

PF07686 // ENSGT00530000063436_0_Domain_4 (676, 799)

ETTIPRSPSVVKSVVGGSVALLCPYNPKD-----RNGLKYWCRWN
GAQ-NGGCPQLVSSEGLVKEHYKDYEGR---LALYEEPGNG---YTVILNQLTTQDAGFY
WCLTDGDTHWWSTVELKV

ENSGT00530000063436_0_Linker_4_5 (799, 804)

VEG--

PF07686 // ENSGT00530000063436_0_Domain_5 (804, 920)

EPNLEV---PTNVTVGVGE--TLNLPCHLPCKFAS--
-YEKFWCKWSSKG--------CKALPSHNEGSGQASVNCSQGNQLISLILNSVTQEDEGW
YWCGVKENLRFRETVAVYVEVKEK-VKGSQDV--S-------------QV----NA-DAA
PGGKVIEPRVR------KIEN----------------------QVVQDPKLFVEDSE-ID
-TGDSAHGRKAPAD-PGSSVGQG--GSSTVLVSTLVPLA--LV-LALGALAVGVVRARHR
--RNVDRVSI----RSYRTDISMSDFE-NSRDFGANDNMGASSI--TQETALGGKDEF--
-MDT--------SENTVETEQPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQANNMTA-NVQDGP--SEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MNLWLWSLYFLPV--------SG

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ALRMLPEVKLEG
ILGGSITIECPRP-----ETSMRLYLCREMAK-SGSCVTVISN---NHFVRKEYQHRVTL
ELC-----PDENLFLVKVTELTKNDSGVYACGAGWRTDRG--KTQ---------QVTLDI
HS----------EYEPFWEKEP-----IPEP--------PVWFQM---------TS---W
FQMPAPASSFEFISKV---------TTPA--RRTEVLTTHHPSPTTA--ITHR--PHVSR
AS----------------------------------------SVVAAKPTTPLPS-----
----TTV-SKTSAPERLRRPQTASYNQHTR-LHRQRL---NH------GPASQME-DQ--
-----GFHMLIPIILGLILLALL----GLLVKRVIQKRK-A-LS-RRARRLAVRMSALE-
G---SQRPL-S------QRPR----------------VSQWPRS-----QNNVYSVCPRR
AGG----AQAAGER-------------E----APGPSPGR-----S--------------
-----------------------APSAPP--QVSEAPWPHVS--SLKTSCEY------MS
FYHQPAAKMENT----DDYVNVPAR-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MGGEA-----PAKPGEQ-------
------------------------------------------------------------
-KVSSWTLTWPPDGPSPPWA--GSALASPHRRPHLRWL----------------WAGSL-
--PSRLYLCT-----KNILTPFSP----LCRE-E-RSM--------AA

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

VNSLRGPRLVSG
KPGDTVTFQCHYNP-SFINGLQRKYWCRLHPL-TWLCPTVVST---NHYTHLHYGDRVAL
SDF-----PQNGFFVVTLSQLSPEDVGSYRCGIGNRND-V--LFS---------SMNLTI
SAGPPS--TIP-GVIPASGE-----LVRTSFGIASP-ATNRWTPGT--------------
----------------------------T--QTIGRQEAGWDRV----------------
-----------------------------------------------------GS-----
----TPGISKRTASA---------------------------------------------
------------------------------------KRRRTPGT-TGAVVADPVSQVES-
T----IWAT-V------SIPES-------------------PASAIRGMSNTTEGVWVWG
ARG----SV--TNSAR---AS---EEGREARTTEADRPREEA--ER--------------
--------VRTGLDADWMITGTSRPSTL----VSE----KWMWETLREA-----------
---RLVS-------------KPQDLGSIEGTTPSAGVWTLGPT-----------------
------------II-EIAS-MEG-STKGDLD----------------------SPT----
-----GDSGPQATPSQDLAAG------------PLR--PP--------------------
-------GTGFSM--NRAICPGF--NIPKGIRFSAY-PQ--SVLCV--------------
---CA---AQETESATGITLIQMTRFL-ELTFQAD-ELLRMER-------KLLQ-DDS--
-PRIHATM-----TVPERVSGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWSFYFLSV--------SGALRTLPEI

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

QVDG
ELGGSVTIECPLPL---PETHVRIYLCRETAD-SKRCSTVVS----NKFVKEEYRDRVTL
QPC-----PDKNLFQVEVTDLTESDSGVYACGTGKRTNRG--KTQ---------KVTLNV
HSE----------YEPFWEKEP-----PQWF--------PKFP--------HL-PH---W
LQMLPHASSSEFTDKA---------TMPT--QRTEAPPVQHLYPTSR--ITHH--PQVSR
AT----------------------------------------SVATAKPTTLLPS-----
----TTA-SKTSALARLLKSRTASYNHHTR-LHKQRAFNYG--------SQSERE-GQ--
-----EFHILIPTILGLCLLALL----VLVVKRAIERRT-A-LS-RRARRRAVRMRALE-
S---ARRPR-S------QRPR----------------AQQRPRC-----QNNLYSACPRR
ARG----ADAAG------------DG-E----APVPGPGA-----L--------------
-----------------------TPPAPP--P----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWPLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KVEG
ELGGSVTIKCPL-----PEMHVRIYLCREMAG-SGTCGTVVST---TNFIKAEYKGRVTL
KQY-----PHKNLFLVEVTQLTESDSGVYACGAGMNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPAYASSSKFVTRV---------TTPA--QRGKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVAGDKPRTFLPS-----
----TTA-SKISALEGLLKPQTPSYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTILGLFLLALL----GLVVKRAVERRK-A-LS-RRARRLAVRMRALE-
S---SQRPR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------TG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWLHAP--SLKTSCEY------VS
LYHQPAAMMEDSD--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MDGEVPTK------------PRK--------QK

PF07686 // ENSGT00530000063436_0_Domain_1 (229, 361)

ANALTGPRQVSG
EPGGAVTIQCHYTP-SSINRHQRKYWCRLRPL-TWICHTIVSS---NKHIHHRYHGRVAL
TDF-----PQRGLFVVRLSQLSLDDVGRYRCGIGDNNY-M--LSF---------SMNLTI
SAGPFNH-----SATPVARE-----LITGSFATASPA-TNTWTPGT--------------
----------------------------T--QTTDGQGMEWGEV----------------
-----------------------------------------------------AS-----
----TLGTSKTTAST---------------------------------------------
------------------------------------QGGQTPEV-TRSIATGPGSWIEG-
P----IRAT-V------PIPEH-------------------PASKTGIMSNMTEGAWAWG
TRS----SE--TNRAG---VH---EGKREMTSTEAVXXXXXX--XX--------------
--------XXXXXXXXXXXXXXXXXXXX----XXX----XXXXXXLQEA-----------
---TPIS-------------KQRALESTEGMTPTAGVWPLETS-----------------
------------GV-KTAS-VEG-RTEGDLG----------------------TAA----
-----AGIDPRATPSQNLATG------------PRR--PL--------------------
-------DKESSV--KRVTCPGL--NTLQGIKFSAVHIQPHSLLC---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MTLF-----------------TLTCLLAVFPVI--------SMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 336)

PIFGPKELSS
VEGKSVSIKCFYPD-SSVNRHTRKYWCRQGA--SGRCTTLISS---EGYISSDYAGRANL
TNF-----PESNTFVVDIARLTKSDTGHYKCGLGI

ENSGT00530000063436_0_Linker_1_2 (336, 386)

S-SQG--LSF---------DVSLEV
SQG--------------PELPPGTQ

PF07686 // ENSGT00530000063436_0_Domain_2 (386, 531)

VYTADLGKNV--TI-------------------TC
PFKAENAQKKKSLCKKS-GQSCSLVIDSF--ENKG------PSYNERTKFSLK-GTGQLV
FTVFINRLRPSDAGMFVCQVGDQEPSAE----------------QSFAHLQVLK--PEPQ
LVYG-----------DLQGSVNFECNLGPE-VANVPKF------------LCRSRKGGAC
EVIINTLGTSAPDFEGRIMLILTN-MPGFFRVPITGLKKED-AG---HYVCGAHPEGVPA
EGWPIQESQ-LFINEETTI

PF07686 // ENSGT00530000063436_0_Domain_4 (680, 798)

SSVPSVVKGVAGGSVAVLCRYNPKE-----SIGLKSWCRWE
KNQ-NAQCSVLRPN----NNK---YMGR---LALYEEPGNGT--YTVILSQLTAQDAGFY
WCLTDGDVRWRSSVELK

ENSGT00530000063436_0_Linker_4_5 (798, 813)

VVE--GKPNLRV---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 919)

PEDVTVPLGG--TLKLPCHFPCKFYS--
-YVKYWCKWSEQG--------CRTLPSQDEGPSQAFVNCDQNSRVISLTVSPVTKADEGW
YWCGVKQGHSYGDTMAVHVTVDDG-TKGSHDV--G-------------R------A-NAA
PSEGVVEPNGR------I-----I-----------------EPRANIDPSLVVEGRK---
DPGAPAGGSRAVAE-AGSSAGQG--GSSTVLVSTLVPLA--LV-LALGAMALWVVRARHR
--RNVDRISI----RSYRTDISMSDFE-NSRDFGANDNVAVYSV--NQETSLEEKNEC--
-VTTPESI--------TENEEPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQSNNMAA-NAQDGP--KEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MMLS--------------------HLSFLSTVV--------STKSPIFG

PF07686 // ENSGT00530000063436_0_Domain_1 (235, 344)

PKEVSA
VEGSSVSITCYYPS-SSVNRHTRKYWCRQGA--SSSCMTLISS---QGYVSQNYAGRANL
TDF-----QELDAFVVNISHLSQQDSGHYKCGLGIN-TRG--L

ENSGT00530000063436_0_Linker_1_2 (344, 391)

NF---------DVNLKV
SQD--------------PRLLNNTDVYTED

PF07686 // ENSGT00530000063436_0_Domain_2 (391, 533)

IGSTV--TI-------------------NC
PFKSQNAITKKSLCKKT-DESCVLVIDSN--NNVH------PSFIGRVRLVVQ-GTGQLV
FSIVINQLRPSDAGMYVCQAGEG-PSSD----------------KTNVDLQV

ENSGT00530000063436_0_Linker_2_3 (533, 540)

LE--PKP

PF07686 // ENSGT00530000063436_0_Domain_3 (540, 661)

E
LVYG-----------QLRGSVTFDCALGPE-VAHLQKF------------LCRVNKEKSC
DVIINTLGKRNPAFEGRILLSTKDTSDGHFSVQITGLQTGD-AG---KYLCGAHSDGQPQ

ENSGT00530000063436_0_Linker_3_4 (661, 681)

EGWPLQAVQ-LFVNQETIIP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 789)

QTPTVVKGVTGGSVAVLCPYNPKE-----SKSLKNWCRWK
GEN-TGLCPPLVDSQGLVQNK---YNGR---LAVYDEPGNSS--YTVILNQLTTQDAGFY
WCLASSDA

ENSGT00530000063436_0_Linker_4_5 (789, 814)

RWTTMVEIKVVDGKREPSLKI---S

PF07686 // ENSGT00530000063436_0_Domain_5 (814, 920)

KNTTAALGD--TVKLACHYPCKFYS--
-YEKYWCKWSKQG--------CQALPSQDEGPSQAFVSCDQDSRLVSVTLQSITKEDEGW
YWCGVKQGQSLGETAAVYVTVVEK-ARGESPN--S-------------TAPF---Q-GP-
-------------------------------------------------CLTI-------
----SQSGVAPRFA-ILYSAGQG--GSSKVLLSTLVPLG--LV-LALGTVAVWVARVRHR
--KNVDRISI----RSYRTDISMSDFE-NSRDFGGNDNVGASPD--TQETVLEGKVG---
------IT--------RDTEEPKKAKR---------------------------------
-SSKEEA-DMAYSAFLLQSSNIAT-QAQDKP--SEA---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------LYG

PF07686 // ENSGT00530000063436_0_Domain_0 (235, 271)

PRLVIS
HVGGSVTIKCYYST-TSTNKHDRKYWCRESSFSRGRCQVI--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------MDLES-----PAKPGDP-------
------------------------------------------------------------
-KVTSQRAGWRMLVFLLMCLLQVPTVVPAHRRPHLRWL----------------QAGSL-
--LAGPHRWA-----EGAPRPFSC----C----L-GPL--------IAAS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 343)

ALTGPRLVSG
EPGGAVTIQCRYPS-LAINSHLRKYWCRLGPP-AGVCRTVVST---NRYTHLRYRGRVAL
ADF-----PKRGLFVVRLSRLSPEDEGRYRCGLGNSNN-A--LFF---------SMNLTV
SPGLSR--TIP-TATLDYGE-----LITGSFEITSPPATKRCTRGN--------------
----------------------------T--QTTGRQRTGWDTV----------------
-----------------------------------------------------AL-----
----TPGARKTTASA---------------------------------------------
------------------------------------TGRQTPGA-TAVVAPGTGSQVEG-
S----VWAT-V------PTVQS-------------------PASTVRGMTGATERGLVWS
TSN----SE--ATRAR---AS---ERERET-TPGVNRPSEET--DS--------------
--------VSATPGTTETAAGTIRPSTL----ASE----RWMWEPLQEE-----------
---TSAS-------------EPQSLGSIEGTIPAAAVWTSEPT-----------------
------------LI-EMAS-AEG-SSEGDLD----------------------TPA----
-----GDGGPRVMPSQALAGG------------PPG--LP--------------------
-------TEESSV--KSISLEEK--NFSGIL----TPVS--SVLCLLMLVTLVLWKRKLQ
R-KGS---SQKTGRSSGVTLIQMTQFP-ELGLQPG-QPPPVGR-------KRLQ-VDP--
-PPLHASL-----SLPARDPGP--------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDFWLWPLYFLPV--------SGALRILPEV

PF07686 // ENSGT00530000063436_0_Domain_1 (237, 361)

KVEG
ELGGSVTIKCPL-----PEMHVRIYLCREMAG-SGTCGTVVST---TNFIKAEYKGRVTL
KQY-----PRKNLFLVEVTQLTESDSGVYACGAGMNTDRG--KTQ---------KVTLNV
HSE----------YEPSWEEQP-----MPET--------PKWF--------HL-PY---L
FQMPAYASSSKFVTRV---------TTPA--QRGKVPPVHHSSPTTQ--ITHR--PRVSR
AS----------------------------------------SVAGDKPRTFLPS-----
----TTA-SKISALEGLLKPQTPSYNHHTR-LHRQRALDYG--------SQSGRE-GQ--
-----GFHILIPTILGLFLLALL----GLVVKRAVERRK-A-LS-RRARRLAVRMRALE-
S---SQRPR----------------------------GSPRPRS-----QNNIYSACPRR
ARG----ADAAG------------TG-E----APVPGPGA-----P--------------
-----------------------LPPAPL--QVSESPWLHAP--SLKTSCEY------VS
LYHQPAAMMEDSD--SDDYINVPA------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGLL-----------------FLACLLAVFPVI--------SMKS

PF07686 // ENSGT00530000063436_0_Domain_1 (231, 336)

PIFGPQEVSS
VEGRSVSITCYYPD-SSVNRHTRKYWCRQGA--QGRCITLLSS---EGYISRDYEGRANL
INF-----PENNTFVVNIDHLTPGDSGRYKCGLGI

ENSGT00530000063436_0_Linker_1_2 (336, 388)

S-SRG--LSF---------DVNLEV
LRG--------------PGFQNDVEVY

PF07686 // ENSGT00530000063436_0_Domain_2 (388, 508)

VADLHGTV--TI-------------------NC
SFKRVNSE-RKSVCKMR-GQACLTVIDSN--GYVS------SNYADRAEIKIA-GTSQLM
FSFIIKQVQLDDAGTYVCQVGNG-PSA

ENSGT00530000063436_0_Linker_2_3 (508, 559)

E----------------KSKADLQVLK--PKTE
LLYG-----------DLR

PF07686 // ENSGT00530000063436_0_Domain_3 (559, 655)

GSVTFDCALGSK-VKDTARF------------LCRKRNGKDC
DVVINTLGQKAQAFEGRTLLIPKE--KGSFSVHITNLKKED-AG---NYLCGTH

ENSGT00530000063436_0_Linker_3_4 (655, 681)

SDGQLH
EGYPTQPWQ-LFVNEETVMP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 785)

QIPSVVKGVVGGSVAVLCPYNPKE-----ADRLKYWCRWE
DTQ-NGRCQPLVESAGLVEEQ---YNGR---LTLHREPGNGT--YTVILNQLTPEDAGFY
WCLT

ENSGT00530000063436_0_Linker_4_5 (785, 813)

NGDNRWMYTVELKIVEG--EPGLKA---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 911)

PKNAVAQVGE--TFKLSCHFPCKYYS--
-FQKYWCKWSKKG--------CTTLPSQDEGPSQAFVNCDQKSQIISMTLNPVSEADEGW
YWCGVKDGPRYGETVAVYLSVEER-VKESQDI--S-------------QV----D---SA
PGEEVVESSVR------EVES----------------------KVIQNPRLFVDDKT-VK
DIGDPADGSRGSAD-ASSSAGQS--GSSTVLVSTLVPLG--LV-LAAGAVAVAVLRARHR
--KNVDRVSI----RSYRTDISMSDFE-NSKDFGANDNMGASPV--TQETTLGGKDEC--
-GTATEGT---ATENIAETEEPKKAKR---------------------------------
-SSKEEA-DMAYTAFLLQTNNMAA-KVQEDP--EKV---------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MAF-----------------FLACLLALLPV--------VSMK

PF07686 // ENSGT00530000063436_0_Domain_1 (230, 336)

SPIFGPKEVTS
MPGGSVSIQCFYPS-TSVNRHDRKYFCIQNR--RGSCETIVST---NGFVSEKYMGRANI
TNF-----PKNSSFLIELSQLVEEDSGLYKCGVGI

ENSGT00530000063436_0_Linker_1_2 (336, 386)

S-SRG--LSF---------DIKLKV
GQD--------------PDRPNNTD

PF07686 // ENSGT00530000063436_0_Domain_2 (386, 531)

VIVTEVDKTV--TI-------------------NC
PFSKEHTQDRKFLCKKD-GESCSLVIDSL--NQKG------PDYEERVRFKIS-GTGSEV
FAVIISQIKRRDVGMYICGVGEETVAGF----------------QKNVEL

ENSGT00530000063436_0_Linker_2_3 (531, 538)

KLLE--P

PF07686 // ENSGT00530000063436_0_Domain_3 (538, 656)

EPE
LVYA-----------EQRGSVTLNCKLGST-VANVPKF------------LCRMRADKTC
DLVINSKGFVSNATHGRILLSPTN-EAGSFSIMIMQVRKED-AG---LYQCGAQK

ENSGT00530000063436_0_Linker_3_4 (656, 681)

DGQPS
EEGPVQTLQ-LFVSEETTVP

PF07686 // ENSGT00530000063436_0_Domain_4 (681, 787)

KTPLVVKGPSGGSVSVTCHYNPKE-----NNTLKYWCRWK
SSS---HCTKLIDNLGMVNDS---YEGR---VALLDQPQNGT--FTVILNQLTPQDAGYY
WCLSNG

ENSGT00530000063436_0_Linker_4_5 (787, 813)

EHNRKSTVKIEITEG--QPLLIE---

PF07686 // ENSGT00530000063436_0_Domain_5 (813, 918)

PKTVTGQLGK--PLNIACHFPCKFYS--
-YEKYWCKWSNQG--------CKTLASQEEGNSNAFVDCNQSSKIVSLSLNPVTRAHEGW
YWCGVKKGQQYGQTAAVYVSVEEGSKDVVQPV------------------N-------AV
LNEDA------------------------------------------------------V
QPEVRGKGIEEPTV-EGSTEEHS--GSSRILVSTLVPVA--LV-LIVGAVALGVVRARYR
--RFSDRISV----GSYRTDISMSELE-NPRKFGANENTGASVQ----E-TTLGEDEF--
-ITQTENP--------EEIQEPKQVKR---------------------------------
-SSKEEA-DMAYTAFLLQSNNMANEIPLDGP--SDA---------