ENSGT00530000063300_1 : Linker Region Query Results

------------------------------------------------------------
------------------------------------------SVSTYLSTYLN-------
F---------TSLYHNSKMAELFMECEEEEL-EPWQKKVKEVDD----D-----------
---DDDDDEPIFV---GEIASSKPAI-SN--ILNRVNPGL--Y-SRGIKNGALSR--GVT
AAFKPTSQ-----------------HYTNSTSNPVSASP----VHFHP-ESRPSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNPSQAVSNNSS-ELLFD-LTQDTGL---S
---PYQGGPALSIAGVNESSFISK-RPSASEG--NSVNPKKPKPSE---SVSATDSSAVF
PSINSPSQT------------------------SSQAMPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKLDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVAPLQSGSSPT---PSISA-STSTLQLSPPRT-KNITA
K-----NPTKLNTSKPNTP--KS---------------------------NASKSNGSKP
NGNKSKYK--SKTSNVQKKQSTL-----ANSNKKSKVNTALRNLRYH-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKRSED-LRG-ITLVC-LNCDFLADVSGLDNMAKHLSQHETHTCHIVTEKVSVC
IPTSEHL--SD--VQIHFLM------------NLYFSVSKMKLHQK-KNMDVMQIYLKAH
QQHKGKKT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

MVTGPWPSPPTGAWVFEGPRRGAHVGARLPRRRQDRELGHGESDPEPTHEAARRLH---E
SPPFPRLGCQLRNGSRRRRRSVVFRAPPFPPPL-SPPPQGSSQADPLRSRKENRN-NLLP
C---------LESHGNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGANSSTVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPA---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIGRP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSATKSEESL-TVSDKENETCLADQETGCKNIFSCDSN--
-IGADKVEKKTQIQHVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIQETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYDHLR--KDTA
RKLQPK-------------------SHETVTSEAVTVL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYRNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHHPV--STALSVGGINESPRVSK-QLSTFEV--NSINPKRAKLRDGIIEG---NSSAS-
--------------------FPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQRN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSAHQCSKCRLQFLTFKEKMEHKTQYHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDV---ASITTH-FLPKEG-------RRII
L-----KADLKSL-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------PYMNPTSNPVTASP----VNFRP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYIMNSSRVVCNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGMNESLFLSK-RPSTSEV--NSVNPKKPKPSE---SVSGTNSLAVC
PSVKSPSVT------------------------SSQAVPPKGANSSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTANKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNFRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGTSPT---PSNSA-SSSTLQLSPPRT-KNITT
K-----SPTKSNTNKPNTTTTKS---------------------------SPSKPNASKP
NGNKPKYK--PKISNMQKKQSTL-----ANSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFVTDVSGLDNMATHLSQHETHTCQVVLEKVSVC
IPTSEHL--SE--LKNEAPTKEQ------EPGSKEIARP------TMAEGETETSNFESK
QDKAAFSEEKNECDANLFEGSLATKSEESLVSVSDKENVTCLADQKTGSKKIFNCDSN--
-IGADKGEKKEQIQHVCQKME-LKMCQ-SSENINLCDQIKDYN-SSKAKFSSKN-IKDLR
LTS----GDVSIDQFLRRRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSEQTDHIPEENNPSTTETTVDLADGKERS---

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMSESSFLSK-RPSTSEI--NNVNPKKPKPSE---SVSGANSSAVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKSNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKKIARP------NMAERETETSNSEST
QDKAASSEEKNGCNANSFEVSSTTKSEESI-TVSDKENETCLADQETGSKNIFSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMCQ-SSENIILSDQIKDHN-SSEARFSSRN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDNIPGGNNPSTTEATVDLEDEKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MGDFFL-CKKVESP---KKNLRESKQ--REEDDEDPDLIFVG
VEHVHKDAEILFV---GMISNSKP-VVSN--ILNRVTPGS--N-SRRKK-GHFR--QYPA
HVSQPA-------------------NHVTS--MAKAIM-----PVSLS-EGRSTDSPV-T
MKS----SFEP-------------------------------------------------
---------------------------GYKMSSPQVVSPNSS-DSLPP-GT---------
-QRLV--GAMVSGGSRNESSPDSE-RLSTSDI--NSGDSKRVKLRDGIPGV---PSLAV-
--------------------VPSDISSIVS---TNTPSQG--VCNSSNHVQ---------
-----NGVTFPWADANGKAHFNLTNPERANE------------SGLAMTDISSLASQNKT
FDPKKENPIVLLSNFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NIKFMNHMKHHLEFEKQRN-DSWEDHTTCQHCHRQFPTPFQLQCHIDSVHIAM-GP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCLFCLKLFKTAIPYMN-----HCWRHSR-RRVLQCSKCRLQFLTLKEEIEHKTKDHQ
TFKKPEQLQGLPRETKVIIQTSVQP---GSSGM---ASVIV-------------------
--------------------SNT-----------------------------------YP
QPSPVKT-----------------------KKKTAMNTRDSRL-----------------
---------------PCSKDSS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDSS
PLQ---------PKSNFRMAELFMECEEEEL-EPWQRKVEEMQD----D-----------
-----DDDELIFV---GEILSSKPAI-SN--ILNRGIPGS--S-SKGIKNEIFSQXXXXX
XXXXXXXX-----------------XXXXXXXXX-----XXXX--XXX-XXXXXXXXX-X
XXX----XXXX-------------------------------------------------
---------------------------DFASDSLEIDSDE-S-QELFD-LTQDS-E---S
---LSQDNIADDIEAT---------------RA-NSITLQKPKIIE---DVIQVNASASL
SLSISPLES------------------------SSYGMFLKNPDNASFHY----------
-------LEYLRACPKCSTHFTHFETLQFHMKHCCPDMIHTILEST-NIDLTDTENTNKT
SSEK-GKLIMLVSDFYYGRH----------------EGAVD---DEPKTFTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHTLLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGVHRCAKCRLQFLTCKEKLEH-KNQHR
TFIKPKELEGLPSGTKVTIRASVGSVHSRPSTTS---PPSSPSTSSFPLPTPKS-KNTTA
K-----SSTKSAASKSKAGKAKVNKANAS------------------------KANASKA
KASKAKA--RAKPCC-RR----------RYRRRKTTITVALKNVRCN-------------
----RGLHK----CIECHSKIKDFAGHFSIYIQCNFCKYNTNCNKAFVNHMVSSHSNPPS
KRFYIFRKHPGA-FRA-MTLVC-LKCDFLAHSSCLDLMAKHLSQRKNHTCQVIEERVRR-
-GISISEA-GECLK----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MGDNP
F----------QPKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
AAFKPTNQ-----------------HYTNPASNPVAASP----VNFHP-ESRSSDSSV-I
VQP----LSKP-------------------------------------------------
---------------------------GYITNSSRVVSNNSS-ELLFD-LTQDTGS---S
---HYQGGPTLSIPGMNESSFLSK-RPSTSEV--NSVNPKKPKPSD---GVSGINSSAVF
PSVKSLSVT------------------------SPQATSSKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTANKNKT
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSTT---SSISA-STSTLQLSPPRT-KNITA
K-----IPTKSNTTKPSTT--KP---------------------------NTSKPNASKP
NGSKSKYK--SKISNIQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFIADVSGLDNMATHLSQHETHTCQVVIEKVSVC
IPTSEHL--SE--LKNEAPTKEQ------EPVSEEITRT------NMAEGETEISNSESK
QDKTSSEEEKNECVTNSFEGSLATKN-EESITVSNKENDTCLEDQKTGLKNIFSHDSN--
-IDADKVEKEKQIEHVCQKME-LKMCQ-SSGNIISCDQNEDSN-SSEAKFSSKN-VKDLR
LTS----GDVSIDQFLRKRDEPESISSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDDVVSDQTGSVPGENSPSTTETTVDLADEKERS---

------------------------------------------------------------
-------------------------------------------VTTYKKSDLQLD-G-KL
F---------LLKLDNSKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNSSS--H-SRGIKNGALNR--GFT
TSFKPTNQ-----------------RFTNPASNPVAALP----VNFHP-DSRSSDSPV-I
VQP----FSKP-------------------------------------------------
---------------------------GYVTNSSPVLCNNSS-ELLFD-LTQDTGL---S
---HYPGTPALSIAGLNESSFTSK-R-PFSDI--SSVNSKKPKPND---NISGADDSSVL
SSEKPPSVS------------------------SLQVTPLQGANCSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKKHMTYCCPDMINNFLGLN-KIEISNTANEAKT
LDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTLH-DF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSDVESHFRTAHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGPSAT---PSISA-STSTLQLSPAGT-ENVTS
K-----TPTNLDTSTSNTT--VS---------------------------EPSKPNESKS
NGNKSKNK--SKVCNTQKKQSTP-----TNSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLIEKG---
----------I--LKTEAPTKGQ------ESVSKETAR------HNTAEGETGASHSEGK
QDKAPSSEGSVGRDASVCEAAA-AANCEGNVAVSDTEN-------EGSSKNIFSHGSD--
-AGADSMGKEEQTQHTCQEME-PKVHR-SSEHTN------------SSEFSSET-GQNSQ
LMS----GVAGIDQFLRQREKPESVSSDASEQGSVGLEPLMPSEVLEFEATEMLHKGDNS
---SANSNDTVSDETGG--S-PGGSRAETAVDLAEGKERS---

------------------------------------------------------------
-------------------------------------------------------MDNKN
PNQQK------SKYSNSKMEELFMECEEEEL-EPWQRKIEETQN----KDDGG------G
GGDDDDDDELIFV---GEVSSSKPAI-ST--ILNRGNSSS--S-SRGIKNEALG--TGIS
DTFKSKNQ-----------------HYKDPPSDP-----VAGLPRFHP-ESKSSESPH-A
VQN----ISKP-------------------------------------------------
---------------------------ELSKNSSRVDSHGSS-MFLFD-LTNDT-I---P
---LSP--------EMDQTSFGVT-HLPASKV--NSINPPQPKTSQ---GVSETNISLAL
SSKKFSSEAS-----------------------SSQIVVTTGSNTS-SNSK---------
-----NGAPFRKSCPKCNIQFRHLTALRSHMKHCCPDMVNNSLGTF-NIEISSAD-KDDA
GSEK-GKLIMVVNDFYYGRH----------------EGTIE---EELKTYTNFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRIVHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCMKCRLQFLTYKEKIEH-KAQHR
TFIKPKELEGLLPGTKITIRASLGPVQALSSTD----SSCIPS-TSLQILPSTS-TGATT
K-----NL-KNPASKYKTNKQQASVSTAA------------------------KPNTSRS
STNTSKCK--GKQSCKQR----------RQRNRKNAISIALKNLRYC-------------
----QGIHK----CIECHSKIKDFASHFSLSSYCDHCKYNTNCNKAFLNHTAVI------
----LLLLPSFF-HRG-ITLVC-LKCDFLTDASGLDRMAKHLSHRKTHTCQVIVENVS--
ESTSTSEPTSQ-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNN
PFR---------PKSNSKMAELFMECEEEEL-EPWQKKADSQ------D-----------
----ED-DELIFV---GEISSSKPAI-SN--ILNRGNSSS--S-SKGIKNDVHS--PGIP
DIFKTRSQ-----------------YFKDSTSSP-----LSASPRFP--DLKSSSSSA-S
VQN----ASKS-------------------------------------------------
---------------------------DLTKNSSQAEPNSSS-DLLFN-LTPDS-V---T
---SSQDIPAIFR-DMNRTSFTLK-RPSPSKV--NSVSPKKQKSDK---DVYEIDPSASL
FSSDSSTKT------------------------SPQIMPSQDSNTSSVQCK---------
-----DEAPFQEACPKCNVHFNLLESLKQHMKRCCPDMANDFLGSI-KTEVSCDENKDNS
GSEK-GKLIMLVSDFYYGRH----------------EGAVE---EEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVEAHFRASHENTK
NLLCPFCLKVNRMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDH-KTQHR
TFIKPKELEGLPSGTKVTIRASLGPLQSKASTI---PLSCGPSTSSFQVSPPKS-KNTTA
K-----GPTKSTASKSKTSKPHATASTAN------------------------KPNTSKQ
SGGPPKCK--AKSSYKQK----------RQRNRKNKISIALKNLRCR-------------
----RGIHK----CIECRSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMMSSHSNDPS
KRFYIFKKHSGA-LRG-ITLVC-LNCDFLADSSGLDRMAKHLSQRKTHSCQVIIENVS--
QSTSTSEPTSDRLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEIASSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
TAFKPTSH-----------------HYLNP-SNPVAASP----VSFRP-ASRSSDSST-I
VQP----FSKP-------------------------------------------------
---------------------------GYIMNSPRVVFNKSS-QVLFD-LTQDTGL---S
---CYQGVPTLSVAGLNDSSFLSK-RPSVSEV--NSVNPKKPKPNE---STGT-NPSAAV
P-AEPPALM------------------------SPPEGPSKGTNTSSDQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMTYCCPDMINNFLGLA-KTEISSPA---PT
LDSEKGKLIMLVGDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSN-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEVHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGSSAV---PSISA-TTSVLQLSPPRT-E----
------NPSKLNTNKPNAT--KS---------------------------DANKPNGSKP
GGNKSKCK--AKITNMQKKQSAG-----ADGSRKSKANTALRSLRLR-------------
----QGIHE----CIECSSEIKDLANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCGFLTDVSGLDNMAAHLSQHATHTCQVQIDKVSVC
IPTSEHL--SEC-RCSPEISKTI------QGTPGQL-TP------VVFP-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDE
TFQR---------KNIPKMTELFMECEEEEL-EPSQKKVEKTQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKRIKSEPAS--PGIP
EIFRTASQ-----------------RYRDSSSNA-----VTTLPRFHP-ESESSQSSA-T
VDS----ES-K-------------------------------------------------
---------------------------PDSTKNSQVESDNSS-ILLFD-STQES-I---P
---PSQNIPAIFREGMKHTSYVLK-RPSTSKA--NSVTPKKPKTSE---DVPQIKPSTSF
SSTDSPPVT------------------------SSLVRLTKGTNTSP-PYD---------
-----AEAYYLRACPKCNVQFNLLDPLKYHMKHCCPNMITKFLGTIIKSERPCAEDKNEI
DPET-GKLIMLVNEFYYGRH----------------EGVTE---EEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQRCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAVHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPHQSKLPTA---PSGYTPGTSFLQVTPPTF-QNSTA
E-----NPIKSNASKSKTSRPR------------------------ATTSTASKANTSKP
RGHTAKCK--AKPSYKQK----------RQRNRKNKMTLALKNLRCC-------------
----RGIHK----CFECHSKIKDFASHFSIHIHCSFCKYNTNCNKAFVNHMRSSHSNHPG
KRFRIFKKHSRT-LSG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTSDCPLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MDQPCLLSEE-EHDPEPQKSLKETQQ----IDDEDAELIFVG
VEHVNEDSELIFV---GVTSNSKP-IISN--ILNRVTPGS--C-SRRKKYGRLR--KNTY
RS-QPT-------------------SLMVPRSD----------TASRS-ESRSTDSPI-I
IEPLPNPLSKS-------------------------------------------------
---------------------------DYRNNLPQVVPVSSS-ELHSP-LVTF----TSS
WHQPG--RATLSVEGVNESPCVAK-QC-SSEV--SSLNPQTLEFSDGHTGR---YSSAL-
--------------------SPSGAFHIVN---PHQIPPSNGIHASLNHLQ---------
-----TGA----SFPKDNVHF--------N------------NNVLAKPDFANLESPDNT
SDPNKGNLVVLLSDFYYGQH----------------KGDG---QPKQKTYTTFKCLSCLK
VLK-NVKFMNHVKRHLEFEKQWS-DSWENPTTCQHCHRQFPTPFQLERHIDNVHTTQ-EL
STVCRICELSFETDQLLLEHMKDNHKPGELPYVCQVCNYRSS-VFADVETHFRKCHANTK
NLLCPFCLKIFKAGTPYVC-----HFRGHWE-RNVHRCSKCRLQFLTFKEKMEHKTRYHQ
MFKKPKQLEGLPPETKVVIQVSLGPVQPGSEKV---ASITVS-TTDSEPSSPSP-KSKKS
K-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGANSSTVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPA---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIGRP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSATKSEESL-TVSDKENETCLADQETGCKNIFSCDSN--
-IGADKVEKKTQIQHVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLADEKERS---

-------------MLMPASRVGDKTGSSD----------TGRLTRSLPMRQRAGCM---S
APPFPRLGCQLRNGSRRRRRSVVLRAPPFPPPL-SPPPQGSSQADPLRSRKENRS-NLLH
C---------LELHGNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGLSRLS
---HYQGRPTLSIAGMNESSFLSK-RPSTSEV--NNVNAKKPKPSE---SVCGADSSAAS
PSVKSPSVT------------------------SSQAMSAKGANTTSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFADVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPPKSSTSKPNTI--KC---------------------------NTSKPNTSKP
NGSKSKYK--SKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----LGVHK----CIECCSEIKDFANHFPTYVHCSFCRYHTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMAAHLSQRETHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEITRP------NMAERETETSNSESR
QDKAASSEEKNECNANSFEGSPTTKGEESI-RVSDKENDTRLADQETGSKKIFSGDSN--
-IGADKVEEEKQIQHVCQEME-LKMCQ-SSENVILCDQMKDHN-SSEARFSSKN-IKDLR
LTS----DNVSTDQFLRKRDEPESVSSDVSEQGSIRLEPLTPSEVLEYEATEILQKGSGD
--PSPQTGEVVSDQTDNIPEGNSPSTTEATVALADEKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVDD----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPGL--Y-SRGIKNGALSR--GIT
AAFRPPSQ-----------------HYMNSTSNPVSASP----VNFHP-ESRSSSSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GCMTNPSQAVSNSSS-ELLFD-LTQDTGL---S
---HYQGAPTLSIAGINESSFLSK-RPSASEV--NSVNPKKPKPSE---NVPGTNSSTLV
---KSSSQT------------------------PSQVMPSKGANTSSDQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-ETEFSNTAN--KP
VDSEKGKLIMLVNDFYYGKH----------------EGEVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHFRRAHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKLDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVAPLQSGSSPT---PSISA-STSILQLSPPRT-KNLTA
K-----SPTKLNTSKPSTP--KS---------------------------T-----GSKP
NGNKSKYK--SKIPNVQKKQNTL-----ANSNKKSKVNTALRNLRFR-------------
----RGVHK----CIECCSEVKDFTNHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEA-LRG-ISLMC-LNCEFLAGVFDLDNMATHLSQHESHSCHIITGKAPTK
QQEPVSK--E---------------------------IARPNITEGK-----IKTSNAKS
EQDEGSSEAKSGCGADLLEGPSPT-QGEESLTVSDKENDACPADQETGS-KLFLCYSN--
-VGADQAGKGEETQHADQDME-LKRGQ-GSENTAPCDQTEDYH-SSEAKLSSED-IKDLP
LTS----SDVSIDQFLRKRDEPDSVSSDVSEQGSVHLEPLTPSEVLEFEATEILQKGSSD
--LSAKTDKVASDQTDNVPGEDSPSTTETTAHAADEKERS---

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIQETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
RKLQPK-------------------SHETLTSEAVTVL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYRNSSPQVVPNNFS-ELPSPLI-TF----TGS
LHHPV--STALSVGGINESPRVSK-QLSTFEV--NSINPKRAKLRDGIIEG---NSSAS-
--------------------SPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKQNPIVLLSDFYYGQH----------------KGEG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQRN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSAHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------ILNRVNPSS--Y-SRGVKNGAVN--RGIS
AAFKPTNQ-----------------HYVNPSSNPVTPS----PANFHP-ESRSSNSSV-I
VQP----FTKT-------------------------------------------------
---------------------------XXXXXXXXXXXXXXX-XXXXX-XXXXXXXXX--
--XXX--XXXXXXXXVNENSFLSK-RPSASEV--NSVSPKKPKPGENVPGT---NSSAIF
PSVTSPSVXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX---------
-----XXXXXXYCCPDMINSFLGLAKTESSTTN---K---------------------ST
VD---SEKEMIMVDFYYGKH----------------EGXX---XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX
XXICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCXXXXXXXXXXXX-----XXXXXXK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX-XXXXX
X-----XXXXXX-----XXXXXXXX-XXX-----------------------XXXXXXXX
XX--XXXX--XX----------------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
----XXXXX----XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXX-XXG-ITVVC-LNCDFLSGVSDLDNMATHLCQHETHICQVVMKKVSVC
TPTSEHLS--ELKN--EAPSKER------EPEAKXXXXX-----XXXXXXXXXXXX-XX-
KHGKAPSEEKNECDANLCEDSSAA-KSEESLTVSDKENDPCLRDQEIDSKTVSNYDSN--
-TSTDEVEKEKQEQPVCQEAE-PRICT-DSEKIVSCDQKENL--HS-NEASSSK-IKDLR
LAS----GDVID------------------------------------------------
-------------------------------------------

MVTRPWPSPPTGAWVFEGPRRGAHVGARLPRRRQDRELGHGEADPEPTHEAARRLH---E
SPPFPRLGCQLRNGSRRRRRSVVFRAPPFPPPL-SPPPQGSSQADPLRSRKENRN-NLLP
C---------LESHGNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGANSSTVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKAQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPA---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISHMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIGRP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSATKSEESL-TVSDKENETCLADQETGCKNIFSCDSN--
-IGADKVEKKKQI-HVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIQETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYDHLR--KDTA
RKLQPK-------------------SHETVTSEAVTVL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYRNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHHPV--STALSVGGINESPRVSK-QLSTFEV--NSINPKRAKLRDGIIEG---NSSAS-
--------------------FPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQRN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSAHQCSKCRLQFLTFKEKMEHKTQYHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTANSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQAT-------------------SHETLTSEAVTDL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYTNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHHPV--SAALSVGGINEGPHVSK-RLSTFEV--NSINPKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---AQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDN
SSQPKILLVSSEKLDNSKMAELFMECEEEEL-EPWQRRVEETQN----KT----------
-----NFYKLLFL---MDCFSDMPLQ-RK--MNERGNSSS-SS-SRSAKSESLS--PGIP
EIFRTTGR-----------------RFLTRTPSP-----T-----ASP-RSRSSQGSV-T
PQS----LSKP-------------------------------------------------
---------------------------DLTKNSSQDDSDKSS-ILLFD-LTQEPPL---T
---QETQVVQTPPEDSDQSSPLSK-RPSTSQA--DSVAPKKPKISEGISDISDTS-----
---TSPSVT------------------------SSQVVLSQGTDTSTNQNT---------
-----TGTP----CPKCNVMFSLLDPLKYHMQRCCPDMMNDFLANT-DSELPNRENRITT
SSER-GKLIMLVSDFYYGRH----------------EGTLE----EQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFESEHTLLQHMKDT HKPGEMP YVCQVCQYRSS-SFSEVETHFRTSHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGIHRCPKCRLQFLTCKEKTDH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKPSTNL--VSSSTPS-TSLQVLPPNS-KTKAA
K-----NTTKSNASKSKTSKPHAATSTAV------------------------TPKASKA
GRVGSKCK--PPTFYKQK----------KQRNRKSKISAALKNIRCL-------------
----RGIHK----CIECRSKIKDFASHFSTYVHCNICKYSSHCSKAFVNHMMSCHSNHPS
KRFCIFKKKSGP-IRG-ITLVC-LNCDFLTDSSGLDLMAKHLSQRKTHTCQVIKESVS--
ENTSTSEPTSTCLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
L---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGGNSSTIL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLT-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITVVC-LNCDFLSDVSGLDNMATHLSQHTTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIARP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSTTKSEESL-TVSDKENETCLADQETGSKNIFSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEAKFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVGSDQTDDIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
-------------------------------------------------------MDDDK
PFQP---------KNISKTAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
KIFRTASQ-----------------RCRDPPSTP-----VAASPRFHL-VSKSSQSSV-T
VEN----AS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-ILLFD-STQES-L---S
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSE---DVPQINPPTSL
PLTGSPPVT------------------------SSKVMLSKGTNTSP-PYD---------
-----AGADYLRACPKCNVQFNLLDPLKYHMKRCCPDMITKFLGVIVKSERPCDED--KT
DSET-GRLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTRKEKAEH-KAQHR
TFIKPKELEGLPPGAKVTIRASLGPLQSKLPTA---SFGCAPGTSFLQVTPPTS-QNTTA
K-----NPRKSNASRSKTSKPHATTSTASKANTSKPRRRIATSKPHATTSTASKANTSKP
RRRIAKCK--AKPSYKQK----------RQRNRKNKMSLALKNIRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIRCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTTGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------SRIKKYGKLR--KDTA
HKLQPV-------------------SHVTPTSEAVTVL-----PVPEP-ESRLTDSPI-I
IEP----LSEP-------------------------------------------------
---------------------------DYRSNSPQVVPNSSS-ELCS-PLITF----TSS
LQHPV--GSALSVGGLSKSPSASK-RLRTSEV--NSISPKRPKLSDKITGG---QSSVV-
--------------------SSSGIFHTMI---PQQSTPSNGVHTSLSPIQ---------
-----NGALFPTAFPKDKVHFKTINP--VG------------ENRLTKTDLLSLASQNKT
DDLKKGNLIVLLHDFYYGQH----------------PGDR---QPEQKTHTTFKCFSCRK
VLK-NVKFMNHVKHHLELEKQGD-DNWKNHTTCQHCHRQFPTPFQLQRHIESVHTAQ-EP
SAVCRICELSFETDQVLLQHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRTWHANTK
NLLCPFCLKIFKLAAPYMY-----HYRGHWE-KFIHQCSKCRLQFLTFKEKMEHKTRCHQ
MFKKPEQLEGLPPETKVVIQVSLEPLQPGSVEV---ASIIVS-TSDSEPSP---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDNNN
SLQ---------AGRNSKMAELFMECEEEEL-EPWQKKAKETED----------------
----EDDDELIFV---GEISSSKP-AISN--ILNRGNSGS--SSQRSIKSESRN--PGIP
ELFRSTSQ-----------------RFGTPSPTH------------LP-KSKSSLQSS-S
AQN----LPKP-------------------------------------------------
---------------------------XXXXXXXXXXXXXXX-XXXXX-XXXXXXXXX--
--XXX--XXXXXXXXXXXXXX-XX-XXXX-XX--XX-XXXXXXXXXXXXXX---XXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------X--XXXXXXXXXX---------
-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXX-------XXXXXX
XXXXXXXXXXXXXXXXXXXX----------------XXXX---XXXXXXXXXXXXX--XX
XXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX
XXICKICELSFESEHTLLQHMKDTHKPGEMPYICQVCQYRSS-HFSEVETHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQX-XXXXXXXXXXXXXXXXXXXXXXXXX-XX
XXXXXXXXXXXXXXXXVTIRASYAPVPSKPATS---PPSTTPSTSLQ-VPSPNS-KIKPA
K-----TVTKVNVRKSKTSKSRATLSTAS-----------------------KRKARKAS
GIRAKRKP--QATYNKQK----------KQRNRANKLSTALKNLRFR-------------
----RGTHK----CIECRWKIKDFASHFSTFVHCKVCKYNTNCNKAFVNHMM--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MELPCMLCEE-EQEPEVRKREGETKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VISN--ILNRDTPGS--C-SRRKRYAHFR--KGKA
HRLQPV-------------------SHVTPTSEAKTVL-----PVSDS-EPRSADSHI-I
TEP----PSKA-------------------------------------------------
---------------------------DYKNISPEIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RLSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSLSHAQ---------
-----NGEPCPTPFPKDGVHCKLVRP--LG------------ENGLTKTDFPSLASPNKI
VDPTEGNLIVLLRDFYYGEL----------------IGVG---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKCHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFADVDAHFRACHGNTK
NLLCPFCLKIFKTATAYRR-----HHRGHWE-KSFHQCSKCRLQFLTFKEKREHKTQCHQ
MFKKPKQLEGLSPETKVVIQVSLEPLQAGLVEI---ASITVN-TSDFESSPIKS-KSRRS
K-----KEKKS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-----------------------MGD---------------------------------N
L---------FQPKXXXXXXXXXXXXXXXXX-XXXX-------X----XXX---------
XXXXXXXXXXXXX---XXXXXXXXXX-XX--ILNRVNPSS--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVAASP----VNFHP-ESRSSDSSV-I
GQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNNSS-ELLFD-LTQDTEL---S
---HYQGGPTLSIAGMKDSLFLSK-RPSTSEV--NSVNPKKPKPSE---CVSGTNSSAVF
PAVKSPSVT------------------------SPQSVPSKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINDFSELP-KTEFSSTANKNKN
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQV-T---------------------------
------------------I-RASGPLQSGSSTT---PSISA-STSTLQLSPPRT-KNITA
K-----NLIKSNTNKPNTT--KS---------------------------NASKPIASKP
NGNKSKYK--SKIVNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSDH-LRG-INLVC-LNCDFLADVSGLDTMATHLIQHENHTCQVVLEKVSVC
IPTSEHL--SX--XXXXXXXXXX------XXXX--XGIARPHM----TEGDTETSISESK
EDKLSSQEGKNGCDSNSLQGSSVT-KSEECLTVSDKENDTCHEDQEIGSKKVFGSDSN--
-IGADKVEKEKQILHVCQEME-IKTCQ-SSENIISYDQIKDHN-SSETRFSSKN-IKDLR
ITSGD----V-SDQFL-KRNEPESVSSDISEQGSIHLEPLTPSEVLEFEATEILQKGSAD
--PSAKTDEVVSDQTDDIAGENSTSTTDLTVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
-------------------MADLL-CKGEQES---QKTIRESKQ--KDKDDEDAELIFVG
VEHVNKDADILFV---SMISNSQP-VISN--ILNRVTPGS--M-SKRRK-DLQN-----P
ARSKPA-------------------NHTIH--TAKAIM-----PASQP-EWGSTSSPA-T
MES----SFKP-------------------------------------------------
---------------------------AYNMNSPQVP-LNSS-DMLSA-NT---------
-QCLV--GAVCPVKGRDESSPDSK-RLSTSDI--NSRNPKRVKFRAGVPGA---HSLAV-
--------------------VPPNISPIMD---TSPPSQG--VCNSSSHVQ---------
-----SGTSFSWADAKEKAHFCLMVPDTAND-----------FEGLVITEFSRLTNQT--
-DSEKGNLFMSLSDFYYGQH----------------KGDG---KPEEKTQTTFKCISCLK
VLK-NVKFMNHVRHHLELEKQRS-DSWENHTTCQHCHRQFPTPFQLQCHIDSVHTAQ-EL
STVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-AFADVETHFRTCHKNTK
NLLCLFCLKVFKMSGRYMS-----HCQKHCS-KRVFRCPKCRLQFLTLKEEMEHKTKNHQ
TFKKPEQLERLPPETKVIIQISLQQ---ESRGE---ASIVK-------------------
--------------------S---------------------------------------
-----------------------------------------RL-----------------
---------------PCSKGSG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMSESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSAVL
PSVKSPSVT------------------------SSQAMLAKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKSNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIARP------NMAERETETSNSESK
QDKAASSKEKNGCNANSFEGSSTTKSEESI-TVSDKENETCLADQETGSKNIVICDSN--
-IGADKVEKKKQIQHVCPEME-LKTCQ-SSENIILSDQIKDHN-SSEARFSSKN-IKDLR
LAS----DNVSIDQFLRKRHEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLEDEKERS---

------------------------------------------------------------
-------------------------------------------------------MDDDK
PFQP---------KNISKTAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEIPSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
KIFRTASQ-----------------RCRDPPSTP-----VAASPRFHL-VSKSSQSSV-T
VEN----AS-K-------------------------------------------------
---------------------------SDFTKNSQVGSDNSS-ILLFD-STQES-L---S
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSE---DVPQINPPTSL
PLTGSPPVT------------------------SSKVMLSKGTNTSP-PYD---------
-----AGADYLRACPKCNVQFNLLDPLKYHMKRCCPDMITKFLGVIVKSERPCDED--KT
DSET-GRLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTRKEKAEH-KAQHR
TFIKPKELEGLPPGAKVTIRASLGPLQSKLPTA---SFGCAPGTSFLQVTPPTS-QNTTA
K-----NPRKSNASRSKTSKPHATTSTASKANTSKPRRRIATSKPHATTSTASKANTSKP
RRRIAKCK--AKPSYKQK----------RQRNRKNKMSLVLKNIRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIRCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTTGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCLLYE-EDPEPELQKSAKGTKQ----KDDEDAELIFVG
VEHVNEDAELIFV---XXXXXSKP-VVSN--ILNRVTPGS--C-SRRKKYGRLR--RSTA
QSMQPE-------------------SHVPSPSETVTIL-----SESPS-ESRSTDSPI-I
IEP----LSEL-------------------------------------------------
---------------------------DDRNNSSQVVPSSSS-NLDSP-LVTL----TNS
SHHPV--ETVLSSGDMNESPCVSK-R-----L--NNINPKSPKLSDGIIGG---ISSAL-
--------------------SASDNSPTVT---LQQSTSSNDVHTSLSHVQ---------
-----NIAPFPAVFPKDSVHFRPANINPDV------------DNGLAK--ISTL------
------------------------------------------------------------
------------------------------------------------------------
---------------ALLQHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRICHEHTK
NLLCPFCLKIFKAAAPYVC-----HSRRHWG-KSVNHCSKCRLQFLTFKEKMEHKTRCHQ
TFKKPEQLEGLPPETKVVIQVSLGPTQPGSVKE---ASITVS-AMESESSPLRS-KSKIS
K-----KIH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MNKSPHVSK-RLSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSLSHAQ---------
-----NGEPCPTPFPKDSVHCKPVRP--LG------------ENGLTKTDFPSLASPDKI
VDPTEGNLIVLLRDFYYGEH----------------IG----------THTAFKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFADVDAHFRACHGNTE
NLLCPFCLKIFKTATAYRR---------------FHQCSKCR----------EHKTRCHQ
MFKKPKQLEGLSPETKVVIQVSLEPLQAGLVEI---ASITVN-TSDFESSPPKS-KSRRS
K-----KENKS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCLLYE-EDPEPELQKSAKGTKQ----KDDEDAELIFVG
VEHVNEDAELIFV---GMTSNSKP-VVSN--ILNRVTPGS--C-SRRKKYGRLR--RSTA
QSMQPE-------------------SHVPSPSETVTIL-----SESPS-ESRSTDSPI-I
IEP----LSEL-------------------------------------------------
---------------------------DDRNNSSQVVPSSSS-NLDSP-LVTL----TNS
SHHPV--ETVLSSGDMNESPCVSK-RCSTSEV--NNINPKSPKLSDGIIGG---ISSAL-
--------------------SASDNSPTVT---LQQSTSSNDVHTSLSHVQ---------
-----NIAPFPAVFPKDSVHFRPANINPDV------------DNGLAK--ISTLAGQNKN
CDPKTGSLILLLSDFYYGQH----------------KGNG---QPEPKTHSTFKCLSCLK
VLK-NVKFMNHMKHHFELEKQRG-DSWESHTTCQHCYRQFPTPFQLQRHIASVHTAE-EP
CAVCKICELSFESDQALLQHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRICHEHTK
NLLCPFCLKIFKAAAPYVC-----HSRRHWG-KSVNHCSKCRLQFLTFKEKMEHKTRCHQ
TFKKPEQLEGLPPETKVVIQVSLGPTQPGSVKE---ASITVS-AMESESSPLRS-KSKIS
K-----KIH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVED----D-----------
---D-DDGEPIFV---GEIASSKPAN-SN--ILNRVNPGL--Y-SRGIKNGALSR--GVM
AAFKPTSQ-----------------YYTNSTSNPASASP----VNFHP-ESRLSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNPSQAVSNNSS-ELLFD-LTQDTGL---S
---PYQGGPALSIACVNESSFISK-RPSASEG--NSVNPKKPKPSE---SVSGTDSSAVF
PSFNSPSQT------------------------SSQAVPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPGMINNFLKLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHRKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICEICELSFETEHVLLQHMKDNHKPGEMPYIFQVCNYRSS-SFSDVEAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHHCTKCRLQFLTCKEKLDHKTQ---
--------------------QGLPP--------------------GTKLSPPRT-KNITA
K-----NPTKLNTSKPNTP--KS---------------------------NASKSNGSKP
NGNKSKYK--SKTSNVQKKQSTL-----ANSNKKSKVNTALRNLRYG-------------
----QGVHK----CIECCSEIKDFANHFPTYIHCSFCRYNTSCSKVYVNHMMSFHNNRPS
KRFCIFKKHSED-LRG-ITLVC-LHCDFLADVSGLDNMAKHLRQHETHTCHIFLFVSQLL
NIFLNRF--QR--------------------------MSRVHLM----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MERPCMLREE-EQEPEVRKREGETKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VVSN--ILNRDTPGS--C-SRRKRYGHFR--KGNA
HKLQPV-------------------SHVTPTSEAKTVL-----PVSDS-EPRSPESPI-I
TEP----PS---------------------------------------------------
----------------------------------QIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RLSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSLSHAQ---------
-----NGEPCPTPFPKDSVHCKPVRP--LG------------ENGLTKTDFPSLASPDKI
VDPTEGNLIVLLRDFYYGEH----------------IGVG---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQIII------FCRCGCTFPSMPW---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

MAPGPAPRGPGPAPPRGGGRTGAAVG--LPRATRQAP---------------------RG
HPPLPRAPALLSPAAAEVGRRCSAMGGGFASAAAPIPPAG---------PAARSGAARRG
SSG---------RGARLKMAELFMECEEEEL-EPWQKRVKEVEE----D-----------
----DDDDEPIFI---GEISSSKPAS-TY--ILNRINFSS--S-RRQIQNGAPS--RGTV
TSFKSDSH-----------------HYVTPASSPSA---IPVSSVFQS-VSRSTASSV-A
VQP----LSRPVNVSGASQTLQRPVAGCLSTQQMTRSSSGPSQPVSRPVTIPVTTQPVSR
NITVPLVAQPVSRPLTTVTTQPIILNQDYIMDSPPDAPDNTS-GILFG-VRQNSGV---P
---QYQTEPTVSVT----------------------------------------------
-----------------------------------------DTNTASSNIK---------
-----NGGPFPRACPKCNIHFNLMDPLKNHMKYCCPDLVNDFFLGVVQTECSTAMS--KT
TEYEKGKLIMLVNDFYYGKH----------------EGDTQQVQQEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWESHTTCQHCYRQFPTPFQLQCHIESTHTPY-ES
STICKICELSFETEQVLLQHMKDNHKPGEMPYVCQVCNYRSS-AFSDVETHFRTVHENTK
HLLCPFCLKVIKIGAPYMH-----HYMRHQK-KGIYRCTKCRLQFLTCKEKMDHKTQHHR
TFRKPKQLEGLPPGTKVTIRASIGSLQSGSS--------VSTSTSTFQLSPK-A-KNTTA
R-----NHSRSNSNKSKARSKPTTTLKKQ---------------------------NAWT
NSS--SKK--KK-----------------------VTNTALHNLRCR-------------
----LGAHK----CIECYSEIKDFASHFPAYVHCSLCRYNTSCSKAYVNHMMSFHSARPS
KRFWIYKKHSED-LRG-VTVVC-LNCDFLTDGSGLDRMATHLSESHTHACQVIIENVSVD
LPTAEQVSDK--------------------------------------------------
QGLDSSEETKE-GNRNQN-EVASVEKNEENSSLSDTENVPNLELPDNSTKKSLHGKGTRC
DSDHHKQSVGEKQKCIHGESE-LKTCQ-SSDYVVLTDQTKVQN-LDKTTLSAMN-ARDLK
LTLG---EDVSFEQFLRKRNEPESVNSDMSEQGSIHLEPLTPSEVLEHEATEILQKGNIA
--PSSKQAEQLSEQTDKTSQEGSPSRMETTVNKTDENEAS---

------------------------------------------------------------
-------------------------------------------------------MDDDK
PFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RCRDPPSNP-----VAASPRFHL-VSKSSQSSV-T
VEN----AS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-ILLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSE---DVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGADYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCDED--KT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGAKVTIRASLGPLQSKLPTA---PFGCAPGTSFLQVTPPTS-QNTTA
R-----NPRKSNASRSKTSKLHATTSTA------------------------SKVNTSKP
RGRIAKSK--AKPSYKQK----------RQRNRKNKMSLALKNIRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTTGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDKDN
SVQEKGLFLSSWKLDNSKMAELFMECEEEEL-EPWQQKVEESQS----KD----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLKNGSFN--PAIS
NIFKPTSQ-----------------HYRNPSSNA-----LVALPSFHP-ALKSSESS--D
GQT----VSKL-------------------------------------------------
---------------------------DFTKTSPQEDSGACS-VSQSD-STQDIPS----
-----SNILQPRT-GVD-QTLGLK-HPSTSKVN-S-VNPKKPKTSA---SISETRPCSSS
SSQTAPSGA------------------------SSQTVLS-NVNTSSVQSA---------
-----PGSSSLRSCPKCNVKFRLLDPLKCHMKRCCPDMINKFLETL-KSENSKAVSKATT
DSDK-EKLIMLVSDFYYGRH----------------EGTIE---ESQKTHTTFKCFSCTK
VLKNNIRFMNHMKHHLELEKQNN-ETWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKVSRMATPYMN-----HYMRHQK-KGIYRCPKCRLQFLTSKEKTEH-KLEHR
TFIKPKELEGLPPGTKVIIRASLGSSQSRASSP---PSSTIPS-TSLQLSVPKS-KSTT-
----TKNNSKVSANKATTTSPQTVAT------------------------TTGKPSASKP
GTGTTKSK--AKPSYKQK----------RQRTRKNKFSIDLKNLRCH-------------
----QGSHM----CIECRSKIKDFSSHFSTHINCDFCKYTTNCNKAFTNH-MSSHNDHPS
KQLYIFKKQSRA-RRG-ITLVC-LKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVT--
ERAVTSESASDGLFK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MGNGF----G-----------
-----MKXRLIFV---GAIPGSKSPT-SS--ELDEDSSSP--------------------
EAAFPR-F-----------------HPESRSSSP-----EAAFPIFHP-ESRSSYNSD-I
VQN----VPKP-------------------------------------------------
---------------------------DFAKNSSQVESDDSS-DLPFC-LSQNT-V---P
---LSQDGSTIYIEGLDETLPKIK-HSDISKV--NTVNPQKPKINK---SVSEIDPCASW
SLIHYSSAT------------------------SSYVMWSKGTHTVSTANK---------
-----TGTFFVRACPKCNVQFNLLDPLKYHMKVCCPDMVDTFMEMI-KIELSSFENKNMT
GAEK-GKLIMLVSDFYYGRH----------------EGGFD---DEEKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNT-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPL-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQYRSS-SFSDVEAHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCTQCRLQFLTYKEKLVH-KLEHR
TFIKPKELEGLPPGTKVTIRASVGSLHSGPSTSKSILSSSSSASTSLQVSPSKS-KTTTT
G-----SSPRSNASEYKTRKFRATTSTRS------------------------KPSTSKQ
GRGAAKCR--AKTSYKPK----------KKRNRKSKISIALKNLRCR-------------
----RGIYT----CIECHTKIKDFASHFSLFVHCNFCKYSTNCNKAFVNHMLSFHTSQPA
KRFCIFKRLSRT-LRG-ITLVC-LKCDFLVDSSALDLMAKHLSQRKTHTCQVIIENVP--
ESTSAFEPTSALLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------FLSFRKLDNSKMAELVMECEEEEL-EPWQQKVDEIQN----KD----------
-DDDDDDDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLKNYSLN--PAIS
NIFRPANR-----------------HSKNPLHNP-----VAALPRFHP-KSKSSENS--G
VQT----VFKP-------------------------------------------------
---------------------------SFSKTSSQDDPGAS--ILQLD-STKDKPS----
-----YSILKRNTEGIEQTSLGLK-HPSTSKLN-S-VNPKKPKTNE---SVSETNPSSSS
SLNKSPSEA------------------------SSQVVLS-NENTSSIQAE---------
-----TGPPSLRSCPKCKVKFSFLDPLKCHMKRCCPDMINNFLETV-KSEHSTTENKANI
GSDK-EKLIMLVSDFYYGRH----------------EGAVE---EDLKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLEHEKQNS-ESWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQN-KGIYRCQKCRLQFLTCKEKTDH-KLEHR
TFIKPKGLEGLPPGTKVTIRASFGSAQSGSSSP---PSSSIPS-TSLQIAASES-KSTTT
K-----INTKVANKSKTTKCQA-VLT------------------------ATCEPNPSKP
GTGATKSK--AKSSSKQK----------KQRTRKNKFSIALKNLRCH-------------
----QGIHT----CIECHSKIKDFSNHFSTYINCDFCKYTTNCNKAFTNH-MSSHSDHPS
KQFYIFKKHSRA-LRG-ITLVC-LKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVT--
ERSLTSESTSDGLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMSESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSAVL
PSVKSPSVT------------------------SSQAMLAKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKSNTSKPNTV--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKDAEA
AQRFQKI--SR--VYLDSVPLRW------TQLMPVLSFQ------GM-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPYVVDD-DESDPEPQPRSQEPIQVLDEDDSEDAELIFVG
VENVKEDAELIFV---GVTSTSQP-ANSN--ILNRVTPGS--R-LKRKH-DRLR--ETTT
QRLQPS-------------------PPAAPTSEAAIVL-----PVSPA-ESRSTDSPI-I
IEP----LSES-------------------------------------------------
---------------------------DYKSN-SQVVPSSSS-KCCSP-LATL----SSS
ESGPA--RAACSGGGLNESLYVSK-CHF-------SINPQRPERSIEIVEE---LSSAL-
--------------------PPSGPFHTSN---AQQRTPSLEAPKSLNLFV---------
-----NGAPLSG---DPV---------HPRQ-----------DSGSVDTDFSSLASPE-T
FDPKKGSLTLLLSDFYYGQY----------------KGEG---KPEQKTHTTFKCPSCSK
AL-KNVKFMNHTKHHLELERQGSDEAWESHTTCLRCHRLFASPFQLECHIDRVHTAP-DP
CVVCKICELSFETEQVLLEHMKDNHKPGEMPYVCQVCKYRSS-VFADVETHFTKCHVNTK
NLLCPFCLKIFRTGMPYMC-----HCRGHWE-RNGHQCSKCRLQFLTFKEKMEHKTQCHQ
MFRKPKQLEGLPPETKVVIQVSVKPVEAESVEV---ASITVS-TTDWEPSCPRS-QGRLS
Q-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDN
PFP---------SKNNSKMAELFMECEEEEL-EPWQKKVEEILD----E-----------
----DD-DELIFV---GEISSSKPAI-SN--ILNRGNPGS--S-SKGIKNETLT--QGVT
DTFKPTSQ-----------------HYKDPTSNP-----VAALPRFHP-ESKSSQSSV-I
AQN----VSKP-------------------------------------------------
---------------------------DFTKNLSQVESDDSS-DLLFD-LTQDT-I---P
---LSQEGSTIYIEGIDETLPIIK-RSSTSKV--NSVNPKKPKTSE---SGSDISPCASL
SLTNSPSVA------------------------SSHVMISKGTNTSSPHYK---------
-----TGAPFLRSCPRCNVKFNLLDPLKYHMKRCCPDMVNKFLEMI-KAELINTENKNKT
GAEK-GKLIMLVSDFYYGRH----------------EGAVD---DEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHALLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVENHFRASHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCTKCRLQFLTCKEKLDH-KTQHR
TFIKPKELEGLPPGTKVTIRASVGPLHSKPVTTS--PSSSVPSTSSFQISPPRS-KSTTG
K-----NI-KSTTSKSKTSKPHAAVSSAS------------------------KPHAKRQ
GRVASKYKTK-KTSCKQK----------KQRNRKNKISIALKNLRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMVSSHSNHPS
KRFYIFKKHSGI-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVVIENVP--
ESTSTSEPSSECRSNTEISKNVQ------DT-------P------GQ-------------
--CPPSMDTTDACSLFPRNVNY--------LTV-RPPLDCGLKKSDLGESPFLHDWP---
---P------IRLMLIWPEMT-----------------------SRPTKLSTTS-HWGLW
F---------LILRLWVHSDQERPIKSML-QRPSWSLIIL---------AAAL-------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDNDN
PFQ---------PKXXXXXXXXXXXXXXXXX-XXXXXXXXX------------------X
XX--XXXXXXXXX---XXXXXXXX-XXXX--ILNRGTPSS--S-SKELK--TVS--QGVT
DVFKPTSE-----------------FYKHPTSDPVAAL----PRL-HP-ESKSSHSSD-T
VQS----MSKP-------------------------------------------------
---------------------------DFIKTSSQDESDDSS-DLVLD-LTQDSTPLR--
--KHG--TTVYIXXXXXXXXXXXX-XXXXXXX--X--XXXXXXXXXXXXXX---XXXXXX
-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXX---------
-----XXXXXXRCCPDMVNAFLGMIKV--ELSSTEDK---------------------NE
TGAEKGKLIMLVSDFYYGRH----------------EGAV---DEEEKTYTTFKCFSCLK
VLKNNLRFMNHMKHHLELEKQNT-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHTLLQHMKDTHKPGEMPYVCQXXXXXXX-XXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXMN-----HYMKHQK-KGVHRCTKCRLQFLTYKEKLDHRTQ-HR
TFIKPKELEGLPPGTKVTIRASVGPVRSSLSTT---SSKDTPSTSSLQVSPSKS-TSETA
E-----DPTKPY-----ESKYKTRKSYAT-----------------------TSTASSRG
DV--FEYK--AKTYHKQK----------KECNKKNKIGIVLKNLRCL-------------
----RGVHK----CIECRSKIKDFASHFSIYIHCNFCRYKTNCNKAFINHTVSSHSNQPT
KRFYLFKKHSGT-LRG-ITLVC-LKCDFLTDSSGLDLMAKHLSQRKTHTCQVIIENVPGS
ISASGPTS--ARLL--K-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MG-DN
P---------FQPKDNLKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGVLSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVAASP----VNFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYIMSSSRVVSNNSS-ELLFD-LTQETGL---S
---HYQGGTTLSVAGVNESSFLSK-RPSASEV--NSVNPKKPKPCE---GVSGTNSPAEF
SSDKSPSLT------------------------SSQAMPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTANTNKT
IDSEKGKLIMLVNDFYYGKH----------------EGDAQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSPT---PSINA-STSTLQLSPPRT-KNITA
K-----NPTKSNTSKPNTT--KS---------------------------NASKPNGNKP
NGSKSKYK--SKISNLQKKQSTL-----ANSNKKIKVNTALRNLRCR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSSRPS
KRFCIFKEHSED-LRG-ITLVC-LNCDFLTDVSGLDNMAAHLSQHETHTCQVVVEKVSVC
IPTSEHL--SE--LKDEVPIKEQ------ESVSKEIARP------NVAGKKTESSNSESK
QDKASSPEEKNGCDTNLFEDSLATKS-EENTTVSDKENNNCLADKETGSKKIFSYDSN--
-IDADKMEKEKQRQHICQEME-LKMGQ-SSENIISSDQIKDHN-SSEARFSSKN-IKDLW
LPS----GDVSIDQFLRKRDESESVSSDVSEQGSVLLEPLTPSEVLEYESTEILQK-NGD
--SSANTDEVVSDQTNDIPGEESPSTRETTVDLADEKEQS---

------------------------------------------------------------
----------------------------------RLLKYI---------LNIILCTAKSY
FKK---------KLDNSKMAELFMECEEEEL-EPWQKKVEEILV----R-----------
----KE-DIDSFPLYSLFFKPEELSK-EY--ILNRGNPSS--S-SKGIKNETLS--QGVT
DPFKPTSQ-----------------HYKDPTSNP-----VAALPRFHP-ESKSSQNSV-I
VQN----VSKP-------------------------------------------------
---------------------------DFTKNSSQVESDDSS-ELLFD-LTQDT-I---P
---LSQEGSTIYIEGIDETLPILK-RSSASKV--NSVTPKKPKTSE---GISEISPCASL
SLTNSPPVT------------------------SSHVMISKGKYESSAHYK---------
-----TGTPFLRSCPKCNVKFNLLDPLKYHMKRCCPDMVNKFLEMI-KAELAITENKNKT
GAEK-GKLIMLVSDFYYGRH----------------EGAVD---DEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHALLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVESHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGVHRCTKCRLQFLTCKEKLDH-KTQHR
TFIKPKELEGLPPGTKVTIRASIGPLHSKPVTTS--PSSSVPSTSSFQLSPVKS-KSTAA
K-----NPTKSNTSKSK-----TTVSTAT------------------------KPNASKR
GRGASKCKTKTKTSYKQK----------KQRNRKNKISIALKNLRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMVSSHSNHPS
KRFYIFKKHSGT-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLCQRKTHTCQVIIENVP--
KSTSTSEPTSEPTSE---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGANSSTIL
SSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITVVC-LNCDFLSDVSGLDNMATHLSQHTTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIARP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSTTKSEESL-TVSDKENETCLADQETGSKNIFSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMRQ-SSENIILSSQIKDHN-SREARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQQKVAEIEN----KD----------
-D----DDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLRSDSFS--PAFA
NIFKPTSQ-----------------QYRNPSPNP-----VTALPKFHT-ESRSSESS--G
FHA----VSKP-------------------------------------------------
---------------------------SFSKTSSQDDPGASS-VLQLD-STIDTPS----
-----SSILKKSTEGIDQTSLGLK-HPSTSKDN-S-VNPKKPKTNA---SVSETTPSSSS
----SPSSA------------------------FTQVVVS-NEYTSSIQSK---------
-----TGASSLTCCPKCKVKFSYLDPLKYHMKRCCPDMIDKFMEK-----HSGDEKKSRI
TSEK-DKLIMLVGDFYYGRY----------------DGFIE---EELKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLEHEKQNS-ESWESHTTCQHCFRQYPNPFQLQCHIESTHTPH-GF
STICKICELSFETEHLLLQHMKDTHKPGEMPYICQICQFRSS-IFSDVETHFKLTHENTK
NLLCPFCLKVSRMATPYVN-----HYVKHQN-KGVHRCPKCRLQFLTSKEKADH-KLEHR
TFIKPKDLEGLPSGTKVTIRASLGSVQSRPPSP---PPSSIPS-TSLQVSTSES-TTTKS
N-----SKAPANKSKSKISTPQVVLT------------------------AVSKPSTSKL
GPSATKSK--A----KHK----------KQRTRKDKFSLALKNMRCQ-------------
----QGIHT----CIECHSKIKDFPSHFSAVINCDFCKYTTNCNKAFTNH-MSSHNDHPS
KRFCIHKKHSRP-HRG-ITLVC-LKCDFLADTSGLDHMAKHLNQRKTHTCQVVIENVI--
ESTSTSESTSDGLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPASQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------VSVSKTIRSQSWQL-----MD-LGFQ-------
---------SSLTHSMSESSFLSK-RPSTSEV--NNVNPKKPKASE---SVSGANSSAVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITS
K-----NPAKSNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE---------------------------P------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSTTKSEESV-TVSDKENETCLADQETGSKNIVSCDSN--
-IGADKVGKKKEIQDVCQEME-LKMCQ-SSENIILSDQIKDHN-SSEARFSSKN-IKDLR
LAS----DNVSIDQFLRKRHEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGKNPGTTEATVDLEDEKERS---

------------------------------------------------------------
-----------------------------------------------------MDDDNDN
PSQ---------SKNNSKMAELFMECEEEEL-EPWQKKVEEILD----E-----------
----DD-DELIFV---GEISSSKPAI-SN--ILNRGNPSS--S-SKGIKNETLT--QGAT
DPFKPASQ-----------------HYKDPTSNP-----VAALPRCHP-ESKSSQNS--I
VQN----VSKP-------------------------------------------------
---------------------------DFTKNSSQVESDDSS-DLLFD-LTQDT-I---P
---LSQEGSTVYIEGIDQTLPILK-RSSASKV--NSVTPKKPKTNE---SVSEISPCASL
SLTNSPPAT------------------------SSHVMISKGTNTSSSPHK---------
-----TGTPFLRSCPKCNVKFNLLDPLKYHMKRCCPDMVNKFLEMI-KAELAITENKNKT
GAEK-GKLIMLVSDFYYGRH----------------EGAVD---DEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHALLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVESHFRSTHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGVHRCTKCRLQFLTCKEKLDH-KTQHR
TFIKPKELEGLPPGTKVTIRASIGPLHSKPVTSS--PSSSVPSTSSFQLSPPKS-KSTTA
K-----NATKSNTSKSKTSKPHATTSTTS------------------------KPNANKR
GRGASKCKTK--TTYKQK----------KQRNRKNKISIALKNLRCR-------------
----RGVHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMVSSHSNHPT
RRFYIFKKHSGT-LRG-ITLVC-LKCDFLADSSSLDRMAKHLCQRKTHTCQVIIEHVP--
ESTSTSESTSDRLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MERPCMLREE-EQEPEVRKREGETKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VISN--ILNRDTPGS--C-SRRKRYGHFR--KGNA
HKLQPV-------------------SHVTPTSEAKTVL-----S---------TDSPI-I
IEP----PSQA-------------------------------------------------
---------------------------DLKNISPQIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RRSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHNSLSHAQ---------
-----NGEPCPTPFPKDSVHCKPVRP--LG------------ENGLTKTDFPSLASPDKI
VDPTEGNLIVLLRDFYYGEH----------------IGVG---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFADVDAHFRACHGNTK
NLLCPFCLKIFKTATAYRR-----HHRGHWE-KSFHQCSKCRLQFLTFKEKREHKTRCHQ
MFKKPKQLEGLSPETKVVIQVSLEPLQAGLVEI---ASITVN-TSDFESSPPKS-KSRRS
K-----KENKS-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEPSCVLCEE-EQEPKVQKSERETKQ----VDDDDDELILVG
VEHVNEDADVILV---GMTSNLKP-VISN--ILNRVTPGS--C-SRRERYGHFR--KDNA
HKLQPV-------------------T-------AKTVL-----PVSDS-ESRSTLSSV-I
IEP----LSEA-------------------------------------------------
---------------------------DYKNISPQIVPNSFS-ELCSP-LITF----TSS
LQHPV--ETAVSAGDMNKSPHVSK-QLSTSET--NSTNPKRPKLSDGIIRE---YSLTL-
--------------------SPSGIFHT---LTTEQST-PDSVHTSLSHVQ---------
-----NGEPFPTAFPRDNVHCKPVSP--LG------------ENGLKKTDFPSLASQNKI
VDPTEGNLIVLFRDFCYRQH----------------IGDG---QPEPKTHTAFKCLSCLN
VLK-NVKFLNHMKHHLE----------------------FPTPFQLQCHTESVHTLQ-DL
SAVCKICQLYFETDQVLLQHVKDSHKPGEMPYVCQISNYRTS-VFSIPW-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------KSNLQLD-GLLL
P---------FWKLDNFKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
ASFKSTSQ-----------------RYMNPTSNPVTASP----VNFHP-ESRSSDSSG-I
FQP----FSKA-------------------------------------------------
---------------------------GYITNSSQVLSNNSS-ELLFD-LTQDTGL---S
---HYQGGPTLSVTGLNESSFSFK-RPSASEI--NSVDSKKPKSSG---SVPRTDASAVV
PSDKSPSLT------------------------VPQALPSQGADTSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKNHMTYCCPDMINNFLGLT-KMDISNTANETKI
LDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EGQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWESHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVENHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLSSGSSAT---PSVSA-STSVLQLSPPRT-ENTPA
K-----NPTKLNISKPNTI--KL---------------------------DDSKPNENKS
SGSKSKCK--SKISNMQKKQSTV-----ATNNKKSKVNTALRNLRLR-------------
----RGVHE----CIECCSEVKDFAIHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKTHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHEAQTCRVLVEKVSVC
IPTSEHL--SD--KI--------------------------KLLHQKKKMGVVQVFVKLH
PQQEVKKT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-DKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQPT-------------------SHETLTSEAVTDL-----PASHL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHQPV--SAALSVGGINESPHISK-RLSTFEV--NSINAKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---SQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELTKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVN-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVED----D-----------
---D-DDGEPIFV---GEIASSKPAN-SN--ILNRVNPGL--Y-SRGIKNGALSR--GVM
AAFKPTSQ-----------------YYTNSTSNPASASP----VNFHP-ESRLSN-----
------------------------------------------------------------
-----------------------------------TVSNNSS-ELLFD-LTQDTGL---S
---PYQGGPALSIACVNESSFISK-RPSASEG--NRL-----KPSE---SVSGTDSSAVF
PLINSPSQT------------------------SSQVMPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPGMINNFLKLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGD--------KTHTTFKCLSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICEICELSFETEHVLLQHMKDNHKPGEMPYIFQVCNYRSS-SFSDVEAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHHCTKCRLQFLTCKEKLDHKTQ---
--------------------QGLPP--------------------GTKLSPPRT-KNITA
K-----NPTKLNTSKPNTP--KS---------------------------NASKSNGSKP
NGNKSKYK--SKTSNVQKKQSTL-----ANSNKKSKVNTALRNLRYG-------------
----QGVHK----CIECCSEIKDFANHFPTYIHCSFCRYNTSCSKVYVNHMMSFHNNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFLADVSGLDNMAKHLSQHETHTCHIFLFVSQLL
NIFLNRF--QR--------------------------MSRVHLM----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQPT-------------------SHETLTSEAVTDL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHQPV--SAALSVGDINESPHISK-RLSTFEV--NSINPKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELTKTDIMSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MDDS
SFQ---------QTNNSKMAELFMECEEEEL-EPWQKKVEEMQV----ED----------
-NDDDDDDELIFV---GEISSSKPAI-SN--ILNRSNTSSSSS-SKGIKNESLG--PGIS
DMFKPTSQ-----------------HYKDPRSNP-----VAALSRFRP-ESRSSQSSA-V
VQD----TSKS-------------------------------------------------
---------------------------DFSKNSSQVELDNSS-VSLFG-SSQDT-I---P
---LSTGIGKKFLEGVDQTSFGLK-RPSTSKI--NSVNQKKPKTSE---SVSEINLSSSL
SLNSS-SVA------------------------SSQVMVSPGSNTSSIEQK---------
-----TEEPDLRSCPKCNIQFSLLDPLKYHMKRCCPDMLNNFPGTI-KTELSSAEDTTNT
GSEK-EKLIMLVSDFYYGKH----------------GGTLQ---EEPKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWESHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRTSHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCSKCRLQFLTCKEKTDH-KTQHR
TFVKPKELEGLPSGTKVTIRASIGPPQSKPPST---PSSSAASSSSLQVLPPEP-ENTTA
K-----NLTKSYANKAKTTKLQATVSTAN------------------------KPNTSKP
SGGAAKCK---KLSYKQK----------RQRNRKNKLSIALKNLRYV-------------
----FIPD------IQY-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDN
PFQ---------PKSNSKMAELFMECEEEEL-EPWQKKVEEIQD----E-----------
----DD-DELIFV---GEISSSKPAI-ST--ILNRGNPSS--S-SKGIKNETVS--QGVT
DAFKPSSQ-----------------HYKDPTSSP-----VAALPRFHP-ESKSSHSSD-I
VQN----VSKP-------------------------------------------------
---------------------------DFTKNSSQDESDDSS-DTLFD-LTQDT-I---P
---LSQDGSTIYIEGLDETLPIIK-RSSISKV--NSVNPKKPKTGE---SVSEIKPCSSL
SLINFPSVT------------------------SSHVMLSKGTNASSTPPK---------
-----TGTPFLRSCPKCNVQFNLLDPLKYHMKRCCPDMANAFLEMI-KVELSSTENKNKT
GAEK-GKLIMLVSDFYYGRH----------------EGAAD---DEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWESHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHTLLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGVHRCTKCRLQFLTCKEKMDH-KTQHR
TFIKPKELEGLPPGTKVTIRASIGPLHSRPSATT---SKCTPSTSSLQVLPPKS-KSTTA
K-----SPTKSHASKAKTGKPRATTSTAS------------------------RPNASKQ
GRSACKY--KAKTSYKQK----------KQRNRKNKISIALKNLRCH-------------
----RGVHK----CIECRSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMVSSHSNQPA
KRFYIFKKHSGT-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVIIENVP--
ESTSASESTSDAC-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDKDS
----------NRQQSHSKMAELVMECEEEEL-EPWQKKIEASQN----QD----------
-D---DDDELIFV---GEIASSKPAI-SN--ILNRSNSNS--S-SKGLKSVSLN--LGNP
SLFKSGTQ-----------------HYETSASNP-----VAAFPTFHP-ESRSSESSS-I
VQT----VSKP-------------------------------------------------
---------------------------DFSKTSSQVHSGAFS-GLLLD-STKDAPS----
-----SGFLKNITEGMDQTSLGLK-HSSISNVK-SIINPKKPKTSE---SVSETSPSSSS
SLSKPPSEA------------------------SSQPVVS-DFSTSSVQSE---------
-----TGASSLRSCPKCNVKFSFLDPLKYHMKHCCPDMLNNFPDTS-KAEQSSAENKANT
DPDT-GKLIMLVSDFYYGRY----------------EGAGD---EEPKISTTFKCFSCSK
VLKSNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFESEHSLLQHMKETHKPGEMPYVCQVCQFRSS-IFSDVEIHFRASHENTK
CLLCPFCLKVSKMAAPYMN-----HYMKHQK-KGIHRCPKCRLQFLTCKEKAEH-KIEHR
TFIKPKELVGLPAGTKVTIRASLGPGQSRPSST---RSSAAST-SSLQVSSPQS-ESTPP
KSLS-----KTFANKAKRS-KLQIKL------------------------ATSKPNASKS
SSSTTKSK--VKSSCKQK----------KQRDRKNKISRALKNLRFR-------------
----QGIHE----CIECHSKIKDFASHFSTYIQCDFCKYSTNCNKAFINHTVSSHSDHPS
KQFYIFKKHSGT-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVVIENVS--
ESTLTSESISDRLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPFMLDDEDEQDPEPQPRSGEPIQVLDEDADEDAELIFVG
VENVKEDAELIFV---GVTSTSQP-ANSN--ILNRVTPGS--R-LKRKH-DRLR--ATTT
QRLQPS-------------------RPAVPTSEAVVVL-----PASPA-ESRSTDSPI-V
IEP----LSES-------------------------------------------------
---------------------------DYRSSSPQVVPSSSS-KCCSP-LVTL----SSS
ESSPV--KAALSGGDLNENLYVSK-CHF-------SINPQRPDHRIEIVEP---LSSAL-
--------------------SPSGTFHTSH---VQQRTPSFDAPNSLSRLV---------
-----NGAPPSE---DSV---------HPHQ-----------ESGLVEADFSSLASQE-T
FDPKKGSLTLLLSDFYYGQY----------------KGDG---KPEQKTHTTFKCPSCLK
AL-KNVKFMNHTKHHLELERQGSEDAWESHTTCLRCHRQFDSXFQLECHIDRVHTSP-DP
SVVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSS-GFADVEAHFTKCHVNTK
NLLCPFCLKISRTGLLYMC-----HYRGHWE-KSGHQYSQCWLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSVQPVESESVKV---ASITVS-TTDWEPSNPRP-QGRLS
Q-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCLLCEEQDPESEPQKSTKETKQ----MDDEDAELIFVG
VEHVNEDAELIFV---GVTSKAKP-VVSN--ILNRVTPGS--C-SRRKKCGHLR--KNAA
HRLQPT-------------------SQVTSPSETVTVL-----SDSPS-ESRSTDSPI-V
IEP----LPGP-------------------------------------------------
---------------------------AYESSSSQVVPSSSS-GLGSP-LVTL----TSS
LHHPG--KTVFSVGDTNESQCVSK-RCSTSEV--NSTNSKSPKLSDEVKGG---ISSAL-
--------------------SASDISRTLN---LQQSTPWNDLHTSLSHVQ---------
-----NTAPFPAAFPKDSIHFRPTNVNPDM------------ESRLAK--ISSPTSQNKT
FDPKTGSLILLLSDFYYGYH----------------KGDG---QPEQKTHSTFKCLSCLK
VLK-NIKFMNHMKHHFELEKQRG-DSWENHTTCQHCYRQFPTPFQLQRHIASVHTTQ-EP
FAVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQLCNYRSS-AFGDVETHFRVCHENTK
NLLCPFCLKIFKTAAPYVC-----HYRRHWG-KSIHQCSKCRLQFLTFKEKMEHKTRCHQ
MFKKPEQLEGLPPGTKVVIQVSLGPNQPGSVKL---ASITMG-TVESEPSPLKS-KSRIS
K-----NPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCLLREDQDPEPELQKSARETKP----EDDEDAELIFVG
VEHANEDAELIFV---GVKSNSKP-TVSN--ILNRVTPGS--C-SRRKKYGRFR--KNTA
KRLQVEST-----------------SCVSSPSETVTIL-----SDSSP-ESRSTDSPI-I
IEP----LSKF-------------------------------------------------
---------------------------VDKNNSSQVVPSSSS-ELDSP-LVIL----TSS
LQHPV--KTVLSVDDMNESPCVSK-RCSTSEV--NSINPKSPKLSDGIVGG---ISSAL-
--------------------SASVNSHTLA---FQQSTPSNDVHTSLSHIQ---------
-----NIAPFPAVFPKDIVHFKPTNINTDT------------ENGLVK--ISSLASQNKN
CDPKKGSLILLLSDFYYGQH----------------KGNG---QPEPKTHSTFKCLSCLK
VLK-NVKFMNHMKHHFELEKEKG-DSWEKHTTCQHCYRQFPTPFQLLRHIASVHTTE-EP
SAVCKICELSFETDQALLQHMKDNHKPGEMPYVCQLCNYRSS-AFTDVETHFRICHENTK
NLLCPFCLKIFKTAAPYVC-----HYRRHWG-KSVNQCSKCRLQFLTFKEKMEHKTQYHQ
MFKKPEQLEGLPPDTKVVIQVSLEPSLPGSVKV---ASITVS-TIESEPSPLRS-KSRIS
K-----KIHSF-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---RYQGRPTLSIAGMNESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSAAL
PSVKSPSVT------------------------SSQAMSAKGANTTSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMISNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKSNTSKPNTI--KS---------------------------NTSKPNTSKP
NGSKSKYK--SKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----LGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLMC-LNCDFLRDVSGLDNMATHLSHHETHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------KPVSKEITRP------NMAERETETSNSESK
QDKAASAEENNECNANSFEGSSTTK----L-TVSDKENDTRLADQETGSKKIFGGDSN--
-IVADKVEKEKQIQHVCQEME-LKMCQ-SSENMILCDRIKDHN-SSEARFSSKN-IKDLQ
LTS----DNVSTDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSDD
--PSPQTEEVVSEQTDNIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNKDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQPT-------------------SHETLTSEAVTDL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHQPV--SAALSVGGINESPHISK-RLSTFEV--NSINPKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKGNIHFKPINTNLDR------------ENELTKTDVLSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MDQPLVICDE--EDPEPQKSLQETKQ----IDDEDAELIFVG
VEHVSEDAELIFV---GVSSDSKP-ASSN--ILNRVTPGS--R-LRR-KCGHLR--KSSA
QRVQPT-------------------SRVAPESETVTIL-----PASPS-ESRSTDSPI-I
IEP----LSEP-------------------------------------------------
---------------------------DCKNNSPQDVPSSSS-ESCC--LVTS----TSS
LHHPA--RAVLSIGDLNESPRVLK-RRITSEV--NGINPQRSKLNDGLVEE----YSAL-
--------------------SPSGNYSTVN---PQPSAPSSEVHVPVNHVE---------
-----NGAPFP----EDSVHS-------SR------------ENGLTKADFSSLAGQNKT
LDPKKGNLTLLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCLK
VLK-NVKFMNHTKHHLELEKQGS-DSWETHTTCQHCHRQFPSPFQLERHIDSVHTAP-EP
STVCRICELSFETDQVLLQHMKDNHKPGEMPYVCQICNYRSS-VFADVETHFRKCHVNTK
NLLCPFCLKIFKTGSPYMC-----HYRGHWE-RSIHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSMEPRQSGSVKM---ASITVS-TTDCEPSSPRS-KGRAS
K-----KPHQ--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVDE----E-----------
---D-DDDEPIFV---GEIASSKPAI-SN--ILNRVNPGL--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNSASNPVSASP----VNFHP-ESRSSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GCITNASQTVSNNSS-ELLFD-LTQDAGL---S
---HYQRGPTLSMTGISESSCSSK-RPSASEA--DSVNPKKPKPSE---SVSGKNSPAVF
PSVKSSPQT------------------------PPQVTPSKGANTSSDQSK---------
-----NGAPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHFRRSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKLDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVAPLQSGSSPT---PSISA-STSTLQLSPPRT-KNLTA
K-----NPTKLSLSKPNTH--KS---------------------------SASKTSGNKP
NGNKSKYK--SKISNVQKKQSTL-----ANSNKKSKVNTALRNLRYR-------------
----RGVHN----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKSYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LSCEFQTDVSGLDNMATHLSQHETHVCHIVTEKVSVC
IPTSEHL--SE-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
----------------------------------------------------------GE
D-SR--------PKNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VADLPRFHP-VSKPSQSSV-T
VEN----VSKP-------------------------------------------------
---------------------------DT-----QLVSDGSG-ISIQ-------------
------DNPEFL-------------------------------------------KHMN-
-------LS------------------------LKSPYFIVGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKVKL---FSKFVPSLQKPFREAKIADGKT
EKQAVNRITFL--KFRFR------------------------------DFSLVISLNFCS
YWQIVYRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLLLRTKVTIRASLGPHQSKLPTA---PFGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNASRSKTSKPHAPTSTAS------------------------KARTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLKLGI-----------------
-------------GLKCHK--------------INMALYNKINKILFVSCFSSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPASGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------M-TV
P---------FNQKDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGIKNGILNR--GFT
ASFKPTSQ-----------------RCLNSASNPVAALP----VNFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYVTNSPRVLSTNSS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGLNETSFLSK-RPSGSDI--SSVNPKKPKPSE---NISGTDASSVI
SSEKSPSVI------------------------SLQVVPSQGVNCSSSQSK---------
-----NGTTFPRACPKCDIHFNLLDPLKNHMTYCCPDMINNFLGLT-KADNLNSANEAKT
LESEKGKLIMLVNDFYYGKH----------------EGDVL---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSEVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVT---PSISP-STSTLQLSPPEP-DNVTA
K-----NHVKLTTSTANTA--IS---------------------------DPSKANESKS
NGSKSKNK--SKVANMQKKQSTL-----SSSNKKSQVNTALRNLRLR-------------
----RGVHG----CIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRYCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCRVLVEKVSVC
IPTSERL--SE--IKTEAPTKGQ------EPVSKETAR------HSRAEGEPGASHSGSK
QDKVPSSEEGTGCDASVCEAAAATD-CEKDVTVSDTEN-------VSSSKNILSQDPD--
-VGTDTMEKEEQTHHACQEME-LKVDQ-SSESTNPCDQSKEHN-PTEAELSSET-QQDLQ
LTS----GDVSIDQFLRQGDEPKSVNSDASDQGSVRLEPLTPSEVLEYEAAEILHDGDD-
--PSANTSDTVSDQTGGSPGGSSPCRAETAVDLADGKERN---

------------------------------------------------------------
-------------------------------------------------------MDDDN
SLQ---------P----KXXXXXXXXXXXXX-XXXXXXXXXXXX---XXXXXXXXXXXXX
XX--XXXXXXXXX---XXXXXXXX-XXXX--XXXXXXXXX--XXXXXXXXXXXX--XXXX
XXXXX---------------------XX----XXXX----------XX-XXXXXXXXX-X
XXX----XXXX-------------------------------------------------
---------------------------XXXXXXXXXXXXXXX-XXXXX-XXXXXXXXX--
--XXX--XXXXXXXMDQSLP-LLK-RPSTSGV--DSVDPKRPKLYEGISEM---CELSSS
----S-SMTFSEIL------------------------LSQGLD-TSFQYT---------
-----IGTPCPGACPKCNVQFRLLDSLKLHMKXXXXXXXXXXXXXXXXXXXXX-XXXXXX
XXXXXXXXXXXXXXXXXXXX----------------XXXX---XXXXXXXXXXX-XX-XX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX
XXICKICELSFESEHILLQHMKDTHKPGEMPYVCQVCQYRSS-SFSEVETHFRTSHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKTDHKAQ-HR
TFIKPKELEGLPPGTKVTIRASLGPPQLKPTPF---PSGSTPST-SLQVLPPNS-KTKTA
K-----GIPKPNAGRSKTSKPRASTST-P-----------------------SKRKAPKA
RGVRYKCK--LQVCPRPK----------KQRNRKSKISTALRNLRFR-------------
----RGVHK----CIECHSKIKDFASHFSTYGHCNSCKYNSNCSKAFVNHMMXXXXXXXX
XXXXXXXXXXXX-XXG-ITVVC-L-CDFMADSSGLDLMAKHLSQRKTHTCQVIKESVSEN
TSSSESSS--SCLL--K-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPFMLDDEDEQDPEPQPRSGEPIQVLDDDAAEDAELIFVG
VEKVKEDAELIFV---GVTSASQP-ANSN--ILNRVTPGS--R-LKRKH-DRLR--ATTT
QRLQPS-------------------RPAAPTSEAVVVL-----PASPA-ESRSTDSPI-V
IEP----LSES-------------------------------------------------
---------------------------DYRSSSPQVVPSSSS-KCCSP-LVTL----SSS
ENSPV--KAALS-GDLNENLYVSK-CHF-------SINPQRPDHSIEIVEP---LSSAL-
--------------------PPSGTFHTSN---MQQRTPSFDAPNSLSRLV---------
-----NGAPPSE---DSA---------HPRQ-----------DSGLAEADFSSPASQE-T
FDPKKGSLTLLLSDFYYGQY----------------KGDG---KPEQKTHTTFKCPSCLK
AL-KNVKFMNHTKHHLELERQGSEDAWESHTTCLRCHRQFDSPFQLECHIDRVHTSP-DP
SVVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSS-GFADVETHFTKCHVNTK
NLLCPFCLKIFKTGMPYMC-----HYRGHWE-RSGHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSVQPVESESVKV---ASITVS-TTDWEPSNPQP-QGRLP
Q-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-PQV---------NHISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VADLPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSG---DVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCAEDKNKT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPHQSKLPTA---PFGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNASRSKTSKPHAPTSTAS------------------------KARTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNLRCR-------------
----RGIHK--CI--ECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPASG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MERPCMLREE-EQEPEVRKREGETKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VVSN--ILNRDTPGS--C-SRRKRYGHFR--KGNA
HKSQPV-------------------SHVTPTSEAKTVL-----S---------TDSPI-I
IEP----PSQA-------------------------------------------------
---------------------------DLKNISPQIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RLSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSLSHAQ---------
-----NGEPCPTPFPKDSVHCKPVRP--LG------------ENGLTKTDFPSLASPDKI
VDPTEGNLIVLLRDFYYGEH----------------IGVG---H--------FKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFADVDAHFRACHGNTK
NLLCPFCLKIFKTATAYRR-----HHRGHWE-KSFHQCSKCRLQFLTFKEKREHKTRCHQ
MFKKPKQLEGLSPETKVVIQVSLEPLQAGLVEI---ASITVN-TSDFESSPPNL-KVGGQ
K-----KKTKVNSAFSKSEASISVK-----------------------------------
VKNPIKNK------------------------KIEL------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNS
PFQ---------QKNNSKMAELFMECEEEEL-EPWQKKVEETQV----ED----------
----DDDDELIFV---GEISSSKPAI-SN--ILNRSNTSS--S-SKGIKNESLG--PGIP
DIFKPASQ-----------------HYKDPTSNP-----VAALPRFHP-ESKSSQSSA-I
VQN----ISKS-------------------------------------------------
---------------------------DFSKNSSQVQLDNSS-VLLFD-SSQDT-I---P
---LSAGVG--------QTSFGLK-RPSASKI--NSVNPKKPKTGK---RVSEINPSSSL
SLNNS-SEA------------------------SSQVMVSPGPNKSSTEQK---------
-----TEEPLLRSCPKCNIQYNLLDPLKYHMKRCCPDMLNNFLGTI-KTELSSAEDTTST
GSEK-EKLIMLVSDFYYGKH----------------EGAVE---EEPKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRTSHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCSKCRLQFLTCKEKTDH-KIQHR
TFIKPKELEGLPPGTKVTIRASFGPPQSKPSST---TSSSVPVSSCLQVLPPES-KNTTA
K-----NLTKSYASKSKTTKPQATGSTAN------------------------KPNTSKP
SGGTAKCK--AKLPCKQK----------RQRNRKNKLTTALKNLRCH-------------
----RGIYK----CIECRSKIKDFANHFSIFINCNFCKYNTNCNKAFVNHMMSSHTTHPS
KRFYIFKKHSGT-FRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVVIENVS--
ESTSTSEPTSDCLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------VVTIYRKSALQLN---GQ
L---------FQPKYNSKMAELFMECEEEEL-EPWQKKVKEVDD----D-----------
-----DDDEPIFV---GEIASSKPAI-SN--ILNRVNPGL--Y-SRGIKNGALSR--GIT
ATFKPTSQ-----------------HYTNSTSNPVSASP----VNFHP-ESRSSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYIMNPSQVVSNNSS-ELLFD-LTQDTGL---S
---PYQGGQTLSVTGMNESSFLSK-RPSASEV--NSVNPKKPKPSE---SVSGTDSSAVF
PSIKSPSQT------------------------SSQATPSKGAHTSSDESK---------
-----NATPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKLDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVAPLQSGSSPT---PSISA-STSTLQLSPPRT-KNITA
K-----NPTKLNTSKPSTP--KS---------------------------NASKSNGSKP
NGNKSKYK--SKISNMQKKQSTL-----SNSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFLADVSGLDNMATHLNQHETHTCHIETEKVSVC
IPTSEHL--SE--KLYDQIWLKE------KQKHQVPKVSKMKLYQK-KNMDVMQIYLKAH
QQHKGKKT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MNDSS
TFQQKRVFLSFIKLDTSKMAELFMECEEEEL-EPWQKKIEVSQK----KD----------
----DDDDDLIFV---GEILSSRPAI-SN--ILNRGNPGS--S-SRGIKNEALN--SALP
PIFKATNQ-----------------HYINP-SYP-----VAALSRFHT-ESASSQS-S-I
VQN----ISKP-------------------------------------------------
---------------------------GFSKISSQVGSDASS-LLLFD-STKDT-L---P
---SG---IPKTSTGIHQTLFGVK-HSSASNVS--NDNLKMPKTNE---SVPKASPSSSS
FLSKPYSEA------------------------SSQVIVSTNPNTSSTQSK---------
-----SGTPSQRSCPKCNIKFTFLDHLKCHMKYCCPNRINNLLETL-KAELASDENISNI
GSET-GKLIMLVSDFYYGRH----------------EGATD---EEPKTYATFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-DF
STICKICELSFEGEHILLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRASHENTK
FLLCPFCLKVNRMAAPYMN-----HYMKHQK-KGIYRCTKCRLQFLTCKEKIEH-KTQHR
TFIKPKELEGLPSGTKVTIRASLGPVDSQSAST---PTSGATSTTILQASPPRP-KEKTA
K-----NPSNTFSNKTKTHTTHTTLSTTS------------------------KPKTLEP
STGASKFN--ANLSPKQK----------KQCNKNNKIDLALKNLRCH-------------
----QGIHK----CIECNSKIKDFASHFPRYVGCNFCKYYTSCNKAFVNHMMSAHSNTPS
-KFHIFKKNSRA-LRG-ITLVC-LKCDFLANSSGLDRMAKHLNHRKTHTCQVIIENVS--
ECTSTSKYPSDCLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDT
PFQ---------QKHNSKMAELFMECEEEEL-EPWQKKVEETQV----ED----------
----D-DDELIFV---GEISSSKPAI-SN--ILNRSNTSS--S-SKGIKNEQLG--PGVP
DIFKPESQ-----------------HYKDPTSNP-----VAGLPRFHS-ESKSSQSSS-I
VQN----ISKS-------------------------------------------------
---------------------------GFSKNSSQVQSDNSS-VLLFD-SSQGT-V---P
---LSTGVD--------QTSFGLK-RPSTSKI--SSVNPKKPKTSE---RVSEINPFFS-
----S-SKT------------------------SSKVMVSPGLNISSTELK---------
-----TEEPFLRSCPKCNIQFNILDPLKYHMKRCCPDMLNNFLEAI-KREFSSAKDTTNA
GSEK-EKLIMLVSDFYYGKH----------------EGAME---EEPKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNT-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRTSHENTK
NLLCPFCLKVSKMATPYMN-----HYLKHQK-KGIHRCSKCRLQFLTCKEKTDH-KVQHR
TFIRPKELEGLPPGTKVTIRASFGPPQSKPPST---PSSCAPSSSSLQVLSPES-KNTTA
R-----NVTKSYASRSKTTKPQATVSTAN------------------------KPSTSKP
SGGTAKCK--GKLSCKPK----------RQRNRKSKLNTALKNLRCH-------------
----RGIYK----CIECRSKIKDFANHFSIFINCNFCKYNTNCNKAFVNHMMSSHTTHPS
NRFYIFKKHSRA-FRG-ITVVC-LKCDFLAHSAGLDLMAKHLSQRKTHTCQVVIENVS--
ESTSTSEPTSDCLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGIKNGILNR--GFT
ASFKPTSQ-----------------RCLNSTSNPVAALP----VNFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYVTNSPRVLSNNSS-ELLFD-LTQDTGL---S
---HYQGGSTLSIAGLNEASFLSK-RPSGSDI--SSVNPKKPKPSE---NISGTDASSVI
SSEKSPPVI------------------------SLQVVPSQGANCSSSQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKNHMTYCCPEMINNFLGLT-KADNLNSANEAKT
LESEKGKLIMLVNDFYYGKH----------------EGDAL---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSEVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVT---PSISP-STSILQLSPPEP-DNETA
K-----NHVKLNTSTPNTT--IS---------------------------DPSKANEIKS
NGSKSKYK--AKVSNMQKKQSTL-----SNSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRYCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLVEKVSVC
IPTSERL--SE--IKTEAPTKGQ------EPVSKETAR------HSTAEGEPGASHSESK
QDKAPSSEGGTGCDAGVCEAAAATD-CERDVTVSDKEN-------VSSSQNILSHDPD--
-VGIDTMEKKAQTHHACQEVE-LKVDQ-SSESTDPCDQSKEHN-PTEAELSSET-SQDLQ
LTS----GDVGIDQLLSQEDEPKSVNSDASEQGSVHLEPLTPSEVLEYEATEILHDGDD-
--PSANTSDTVSDQTDGSPGGSSPCRAETAVDLADGKERS---

------------------------------------------------------------
-------------------------------------------------------MDDSN
PFQ---------PKSNPKMAELFMECEEEEL-EPWQKKVEEIKE----E-----------
----DD-DELIFV---GEILSSKPAI-SN--ILNRGNSSS--S-SKGIKSEALS--PGIP
DVFKPTSQ-----------------HYKDPTSSP-----VAALPRFHP-ESKSSHSSV-I
VQN----VSKP-------------------------------------------------
---------------------------GFTKNSSQAESDGSS-ILLFD-LTQDT-I---P
---LSQDIPAAFREGTDQTSFALK-RPSASKV--NSVNSKKPKTSE---NVSEISPSASL
SVINSPSGT------------------------SSQAVLSKGTNTSSTQYK---------
-----TGATVLRACPKCNVQFNLLDPLKYHMKRCCPDMVNNFLGII-KAELSSAENENET
GSEK-GKLIMLVSDFYYGRH----------------EGATE---EEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNT-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDH-KIQHR
TFIKPKELEGLPPGT-VTIRASLGPHQSKPSTT---PSSCTPSTSSLQVSPLKS-KNTTA
K-----NPTKSSASKSKTSKSHATAFTAN------------------------KPRTSKP
SGGTSKCK--TKASSKQK----------RQRNRKNKISIALKNLRCH-------------
----QGIHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMMSFHSSHPG
KRFYIFKKHSGT-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPTSDRLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAQPCLLHKKHEPEL---HSAKETKP----KDDEDAELIFVG
VEHVSDDAELIFV---GETSDSKP-VISN--ILNRVTPGS--Y-SRRKKYGRFR--KNTA
QRLQPA-------------------SHVTSPSETVTVL-----SESPS-ESRSTDSPI-I
IEP----LSDL-------------------------------------------------
---------------------------DDDNDSSQVVPSSSS-EFNSP-VVAS----ASP
LQHPV--PTVLLVEDTNDSPPVSK-RCSTSEV--SSINPKSAKLSDGMAGG---ISSAL-
--------------------STSDDSHTVT---LQQSTLSSDVATSLSCIQ---------
-----NIASFPAVFPKDN-------VHPDM------------ENGLAK--ISSLASQNKT
CDPKKGSLILLLSDFYYGQH----------------KGDG---RHEAKTHSTFKCLSCLK
VLK-NVKFMNHMKHHFELERQKG-DSWEKHTTCQHCYRQFPTPFQLQRHITTVHTAE-EL
SAVCKICELSFETDQALLQHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRVCHENTK
NLLCLFCLKIFKTAAPYEC-----HCKRHWG-KSVNQCSKCRLQFLTFKEKMEHKTRCHQ
MFKKPKQLEGLPPETKVVVQVSLEPSLPGSVKV---ASITVS-TIEYESTPLRS-KSKIS
K-----KVH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVCNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGANSSTVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKAQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPA---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIGRP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSATKSEESL-TVSDKENETCLADQETGCKNIFSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
-------------------------------------------------------SLSSS
PCQP---------KYISKMTELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-RPSTSKV--NSVTPKKPKTSE---NVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDKNKT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKLPTA---PSGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNAGRSKTRKPHAPTSTAS------------------------KAHTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNLSSS-------------
----LSLYHIHCIGLKCGHKI-------------NMALYNKINKILFVSCFSSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPISG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKIKEVDD----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPGL--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNSASNPVSASP----VNFHP-ESRSSNSSV-I
VQP----FSKS-------------------------------------------------
---------------------------GCIMNPSQAVSNNSS-ELLFD-LTQDTGL---S
---HYQRGPTLSIAGINESSFLSK-RPSASEA--NSVNPKKPKPSE---SVSGTNSSAVF
PSVKSPSQT------------------------PSQAMPSKGADTSSDQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHFRRSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKLDHKSQHHR
TFVKPKQLEGLPPGTKVTIRASVAPLQSGSSPT---PSISA-STSTFQLSPPRT-KNLAA
K-----NPTKLNSSKPSAP--KS---------------------------SASKTSGSKP
NGNKPKYK--SKISNVQKKQSTL-----ANSNKKSKVNTALRNLRCP-------------
----GGVYN----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFLADVSGLDNMATHLSQHETHVCHIVTEKVSVC
IPTSEHL--SE--LKNEAPTKEQ------EP--ISKDIARPNISEG-ET---KTSNAK-S
KQDEGSSEEKSGCHANLLEGSSST-QREESLTVSDKENDACLADQETSSKKIFSCDSH--
-IGADKGEKEKEIRHVGQEME-LKTGQ-RSENTTSCDQTDDHS-SSEAEFSSKN-IKDLL
LMS----SDVSIDQFLRKRDEPDSVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSSD
--LSAKTDKVVSGQTYDVPGENSHSTADTRAHLADEKERS---

------------------------------------------------------------
------------------------------------------------------M-G-DC
S---------FQPKDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNSS-----SRGIKNGALNR--GFT
TSFKPTSQ-----------------RFPNPASNPVAALP----VNFHP-DSRSSDCSV-I
VQS----FSKP-------------------------------------------------
---------------------------GYVTNSPTVLSNNSS-ELLFD-LTQDTGL---S
---HYPAAPALSIAGLNESSFSSK-R-PFSDI--SSVNSKKPKPSD---NISGADASSVL
SSEKPPSVL------------------------SLQVAPLQGANCSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKKHMTYCCPDMINNFLGLN-KIEISNTANEAKT
LDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTLH-DF
STICKICELSFETEQNLLQHMKDNHKPGEMPYICQVCNYRSS-LFSDVESHFKTAHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGPSAT---PSISDASTSTLQLSPPRT-ENVTS
K-----NPTTLDTSTQNTT--VS---------------------------EPSKPNESKS
NGNKSKNR--SKVCNTQKKQSTV-----ANSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLIEKVSVC
IPTSERL--SE--LKTEAPTKGQ------ESVSKETAR------HNTAEGETGASPSEGK
QNKAPSSEGSIGRDASVCEAAAAAADCEGNVAVSDTEN-------ESRSKSIFSHGSD--
-AGAENMRKEEQTQHTCQEME-LKVHQ-SSEHMDSWDQTKEHD-SPAADFPSET-GQDSQ
LTS----GVAGIDQFLRQREKPESVSSDASEQGSVGLEPLTPSEVLEYEATEMLHKDDNS
---SANSNDTVSDETGG--S-PGGSRAETAVDLAEGKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEKEL-EPWQKKVKEVDD----D-----------
-----DDDEPIFV---GEIAT----I-SN--ILNRVNPSL--Y-SRGIKNGALSQ--GIT
AAFKPTSQ-----------------HYTNSTSNPASASP----VNFHP-ESRLSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GNIMNPSQAVSNNSS-ELLFD-LTQDTRL---S
---PYQGGPALSIAGVNESSFISK-RPSASER--NSINPKKPKPSE---SVSGTDSSAVF
PSFNSPSQT------------------------SSQAVPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCSDMINNFLGLA-KTEFSNTAN--KS
VDSGKGKLIMLVNDFYYGKH----------------EGDSS-------------------
------------------------ESGENHATCQHCYHQFPTPFQLQCHIETIHTPH-EF
STICKICKLSFETEHVLLQYMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHSRTSHENTK
NLLCPFCLKVIKIATPCMH-----HYMKHQK-KGIHCCTKCRLQFLTFT-----------
------------------IQASVAPLQSGSSPT---PSIST-STSTLQ-----Q-KNITA
K-----NPTKLNRSKPNTP--KS---------------------------NPSKSNGSKP
NGNKSKYK--SKTSNVQKKQSTL-----ANSNKKSKVNTALRNLRYR-------------
----WGVHK----CIECCSEIKDFANHFPTYIHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFLADVSSLDNMAKHLSQHKTHTCHIVTEKDAEA
AQRFQKM-------------------------------SRVHLM----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELIMECEEEEL-EPWQQKVEESQN----KD----------
-DD-DDDDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLKNGSFS--PALS
NIFKPTNQ-----------------HYRNPPSHP-----LIALPSFYP-APKSSESS--D
VQT----VSKP-------------------------------------------------
---------------------------TFLKTSPQDDSGASS-ASLLD-STKDIPS----
-----SNVLQKST-GVN-QTLRLK-HPSSSKVN-S-VNPKKPKTNA---SISETGRGSAS
SLNMSPSEA------------------------SSQVVLS-NMNTSSIQSA---------
-----AGKPSLRSCPKCNVKFSLLDPLKCHMKRCCPDMINKFLETL-KSENSKAVSRAII
GSDK-EKLIMLVSDFYYGRH----------------EGTIE---EDQKAPTTFKCFSCTK
VLKNNIRFMNHMKHHLEFEKQNN-ETWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHLLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKVSRMATPYMN-----HYMRHQK-KGIYRCPKCRLQFLTSKEKIDH-KLEHR
TFIKPKELEGLPPGTKVTIRASLGSIQSRSSSP---PSSTIPS-TSLQLSVPKS-KTTTT
KNTTTKNNSKVSANKVTTTSPQTMST------------------------TTGKTNASKP
GTGTTKSK--AKPSNKQK----------RQRTRKNKFSIDLRNLRCH-------------
----QGTHT----CIECHSKIKDFSSHFSTYINCDFCKYTTNCNKAFTNH-MSSHNDHPS
KQLCIFKKHSRA-LRG-ITLVC-LKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVT--
ERTGTSESTSDGLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------SLSRS
PCQP---------KYISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSE---NVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDKNKT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVSKKHVN--CQSKLPFG---GLPYSFRMDFILNYQKVSTYKYKL
I-----IPIKIVPGRARWLKPVIPAL-------------------------------WEA
ETGXXXXX--XXXXYKQK----------RPRNRKNKMSLALKNLSSS-------------
----LSLYHIHCIGLKCGHKI-------------NMALYNKINKILFVSCFSSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPISG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNK
PFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPGFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSG---DVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDRNKI
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKISKMATPYMN-----HYMKHQN-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPHQSKLPTA---PSGCTPGTSFLQVTPPTS-HNTTA
K-----NPRKSNASRSKTSKPHAPTSTAS------------------------KARTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNL----------------
----------------------------------------------------SSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTSGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNK
PFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-RPSTSKV--NSVTPKKPKTSE---NVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDKNKT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKLPTA---PSGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNAGRSKTRKPHAPTSTAS------------------------KAHTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNLRCR-------------
----RGIHK--CI--ECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPISGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------MSQAEVVHTFI------------------PS----T-----------
-----LEAGYIFH---SNKFKISLYF-LD--ILNRVNPSS--H-SRGIKNGALNR--GFT
TSFKPTSQ-----------------RFSNPASNPVAALP----VKFHP-ESRSADSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSPRVVSNNSS-ELLFD-LTQDTGL---S
---HYQAGPSLSIAGLNESSFSSK-R-PGSDI--SSVNQKKPKPSD---NISGADASSIV
SLEKPPSVM------------------------SLQVTPSQGANCSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKNHMTYCCPDMINNFLGLT-KIEISNTTNDTKA
LDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EELKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTLH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSDVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQPGSSAI---PSISA-STSTLQLSPPRT-ENTTP
K-----NPSKLNTSTPNTT--VP---------------------------DPSQPNESKS
NGNKSKIR--SKVCTTQKKQSTL-----ANSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLIEKVSVC
IPTSERL--SE--LKTEAPTKGQ------ESVSKETAR------HNTAEGETGTSHSEGK
QDKAPSSEEDVGRDASVCEAAA-AVDCAGNETVSDTEQ-------ESSSKNIFSHDSD--
-AGTDNMEKEEQTQHTCEEME-PKAHQ-SSENTD------------SSEFSSES-AQDLQ
LVS----GGVGIDQFLRQRDEPETVSSDASEQGNVRLEPLTPSEVLEYEATEILHKGDGS
---SASINDTMSDQTGG--S-SGGSRAETAGDLEDGKKEA---

------------------------------------------------------------
------------------------------------------------------------
------------------MGDVFL-CKEVESP---KKNLRESKE--SDKDDEDPDLIFVG
VEHVHKDAEILFV---GMISNSKP-VVSN--ILNRVTPGS--N-SRRRK-GHFH--QDPA
HVWQPA-------------------NHVTS--MAKAIR-----PVSPS-EGRSTDSPV-T
TMS----SPES-------------------------------------------------
---------------------------AYKMGSPHVVSPNSS-DSLPP-GT---------
-QHLV--GAMFSGGGRSESSPDSK-RLSTSDI--NSRNSKRVKLRDEIPGV---HSLAV-
--------------------VPSDSSSIIS---TNTPSQG--VCNSSNHVQ---------
-----NGATFPWADANGTAHFNLRNPERANG-----------SDGLVITDISSLASQKKT
FDPRKEIPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NIKFMNHMKHHLEFEKQRN-DSWENHTTCQHCHRQFPAPFQLQCHIDSVHIAM-GP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
YLLCLFCLKLFKTAIPYMN-----HCWRHSR-RRVLRCSKCRLQFLTLKEEIEHKTKNHQ
TFKKPEQLQGLPRETKVIIQASAQP---GSSGV---ASIIV-------------------
--------------------SDT-----------------------------------DP
PPSPVKT-----------------------K-TMATNTGDSRL-----------------
---------------PCSKDSR--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDN
SFQ---------QRSNSKMAELFMECEEEEL-EPWQKKVEPPQV----QD----------
----DDDDELIFV---GEISSSKPAI-SN--ILNRSNTSS--S-SKGIKSESLG--PGIS
DIFKPTRP-----------------HYKVPTSNP-----VAALPRFHP-DSKSSQSSA-V
AQS----ISKS-------------------------------------------------
---------------------------GFSKNSSQVDSDNSS-VSLFD-SSQDT-I---P
---LSTGIQKIFLPGVDQTSFGLK-RPSTSKI--NSVNPKKLKTSE---SISEISPSSSL
SLSNF-SEA------------------------PSQIVVSTDSNTSSIEHK---------
-----TGEPVRRCCPKCNIQFSRLDPLKYHMKRCCPHMLNNFVGTI-KTEPSSAEGTTDT
GSDK-EKLVMLVSDFYYGKH----------------AGALE---EEPKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWESHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCHFRSS-IFSDVETHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCSKCRLQFLTCKEKTDH-KVQHR
TFIKPRELEGLPPGTKVTIRASFGPPQSKQPST---PSSSAPSSSSLEVLPPES-KTTTA
K-----NLTKY-----KTAKFEASGSTAN------------------------KPNTSKS
SGGTAKNK--AKVSCKHK----------RQRNRKSKLSVALKNFRCL-------------
----RGTYK----CIECRTKIKDFANHFSVLINCNFCKYSTNCNKAFVNHMMSCHTSQPN
KRFYIFKKQLGA-FRG-ITLVC-LKCDFLTDSSGVDRMAKHLSQRKTHTCQVVIENVS--
ESTSTSEHTSLTAC----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPFVLCDDEEQEP---------SQ----APDEDAELIFVG
VEHVHDDSELIFV---GVSSNSKP-SNSN--ILNRVTPGS--R-LKRKR-NRLR--AAAT
QRPQPS-------------------GPATPSSDTVIVL-----PASPA-ESRSTDSPI-I
IEP----LSEP-------------------------------------------------
---------------------------DYRSTSPQIVPDSSP-EGS--PLVTV----SSS
KHSPV--RAALSVGDLNESSYVSK-CHSTSGA--NVVNPQRPGLVIEIVEE---HSSAS-
--------------------PPSGTFHTSN---PQPSTPASHVPESLNRVVNGEH-----
------------------------SVHPRQ------------ENGLAQVGFPSVATQ-ET
SDPKKGSLTLLLSDFYYGQH----------------KGDG---QLEQKTHTIFKCPNCLK
ALK-NVKFMNHTKHHVELERQGN-DGWENHTTCQHCHRQFTSPFHLECHVDRVHTAP-NP
ATVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSS-AFADVESHFRKCHVNTK
NLLCPFCLKIFKTGTPYMC-----HYRGHWE-KNGHQCSKCRLQFLTFKEKMEHKTRCHQ
MFKRPKHLDGLPPDTKVVIQVSAEPAESESVKV---ASITVS-TTDWEPSSPKS-QGRPS
K-----RSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCILCEE-EQEPEPQQNIEETKQ----VDDEDGELIFVG
VEHVNDDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--C-SRRKKYGHLR--KGTT
CKLQPI-------------------SHVTPVSEAVTAL-----PVSES-ESRSTESPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKSNSPQVVPNSSS-ELCS-PLITF----TNS
LQHPG--GAALSVGGMNKSPCISK-QLSTAEV--NNVNPKRLKLSDGIIGG---HASAL-
--------------------SPSGIFHTVT---AEQSTPSNSVHTSLSHVQ---------
-----NGAPFPTAFPKDSVHFNPADP--VK------------ENRQAKTDFLRLASQNQV
VDPKKGSLVILLRDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCLK
VLK-NVKFMNHMKHHLELEKQRG-DSWESYTTCQHCHRQFPTPFQLQCHIESVHTTQ-EP
STVCRICELSFKTDQILLQHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWE-KSVHHCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSLGPLHPESLEV---ASITVS-TSDSEPSPPRS-KSKVS
K-----KPR---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------SLSSS
PCQP---------KYISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-RPSTSKV--NSVTPKKPKTSE---NVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDKNKT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKLPTA---PSGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNAGRSKTRKPHAPTSTAS------------------------KAHTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNLRCR-------------
----RGIHK--CI--ECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPISG-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------VGDNT
F----------QPEYNSKMAELFMECEEEEL-EPWQKKVKEVDD----D-----------
-----DDDEPIFV---GEITSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVAASP----VNFHP-ESRSSDSSV-I
VQP----LSKP-------------------------------------------------
---------------------------GYIMNSSRVVSSNSS-ELLFD-LTQDTGL---P
---HYQGGPTLSIAGMNESSFLSK-RPSTSEV--NSVNPKKSKPSE---GVSGTDSSAIF
PSVKSLSVT------------------------SPQAVPSKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTAHKNKT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTYTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSTT---PSISA-STSTLQLSPPRT-KNITA
K-----SPTRSITSKPNTA--KP---------------------------IASKPNASKP
NGSKSKYK--SKISNMQRKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKYSED-LRG-ITLVC-LNCDFLTDVSGLDNMATHLSQHETHACQVVLEKVSVC
IPTSEHL--SE--LKNEAANKEQ------EPVSEEIPRP------NMAEGERETSNSESK
QDEASSEEIKNGCDANLFTGSSAAKN-EEGVSVSDKENDTCLGDQETGSKNIFSYDSV--
-TGADKVEKEKQIEHICQETE-LKMCH-NSENIVSCDQTEERN-TGEVIFSSKN-IKGLR
LPS----GDVSIDQLR-KRDXXXXXXXXXXXXASIQFGALTPSEVLEYEATRNQK--SSV
--DPAKTDEVESDQTDGIPGENH-STTETTVDLADEKEKS---

------------------------------------------------------------
------------------------------------------------------------
------------------MAHLFP-CEEAQAPEPLEKTIRGSKP--RDD--DNAEVTFVR
MEGVSEDAEILFV---RVISNSKP-VISN--ILNRVTTDL--P-SKRKK-SHVG--RAPA
CALQPA-------------------NG---ASMAAAVS-----PASQS-EWGEIAGPA-M
FKP----SSKS-------------------------------------------------
---------------------------DSKTSSLQVVLHSSS-DLLSP-WP---------
-HCLP--GVALPVGGLDESPQDSK-RCPTSEVNMNGGDPKRPKLSDGIPGG---HSSVV-
--------------------ASSGMSPTKN---VSTALKG--VLSS-SHIR---------
-----NGVAFPGAHTGDQIHLNPIHPDRVGS-----------LERLEKADFSRPASQNKT
ADSKKENLIMLLDDFYYGQH----------------TGDR---QPEQKTHTAFKCLSCLK
VLK-NVKFITHVRNHLELEKQRG-DSWEIHTTCQHCHRQFPTPFQLQCHIESVHASQ-GP
SPVCKICELSFETDQVLLEHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRTCHENTK
TLLCLFCLRIFKAATSYVN-----HAWNHWN-KRVFQCSKCRLQFLTLKEKSEHQTKNHQ
TFKKPEQLAGLPPGTEVRIRTSAHL---GPRGA---APAIE-------------------
--------------------SKSHPC--------------------------------HL
KK----------------------------LKGIATDTKLSRHVAER-------------
----VLSKN----VLPTSRDSERLN-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------VGSADERPHYSK-QVSTSDM--NSGNPKGLKLSDTIPGD---TS----
----------------------SGISPTVN---TSTPSKG--VHTSSSRGR---------
-----KEASFPQACSSDKTYFSLRNPVIENC-----------FEGQVETDLSRIANRHKT
FNTKKRNQILFHHVLYYGQH----------------EGGG---QLEQNTHTIFKCLSCLK
VLK-NVKFMNHMKHHLELERQRS-DSWESHITCQHCHQQFPTPFQLQDHVESVHITH-EP
SAVCKICELSFEAG-----HIKHTHKHGEMPYVYQVCN----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MELPCMLCEE-EQEPEVRKREGETKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VISN--ILNRDTPGS--C-SRRKRYAHFR--KGKA
HRLQPV-------------------SHVTPTSEAKTVL-----PVSDS-EPRSPDSPI-I
TEP----PSKA-------------------------------------------------
---------------------------DYKNISPEIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RLSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSLSHAQ---------
-----NGEPCPTPFPKDGVHW---------------------ENGLTKTDFPSLASPNKI
VDPTEGNLIVLLRDFYYGEL----------------IGVG---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFCRCGCTFPSMPW---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----GWLFLSFWKLDNSKMAELFMECEEEEL-EPWQQKVEEVQN----KD----------
-D----DDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLKNDSLN--PAIS
NIFKPANR-----------------HYRNPSPNP-----VAALPRFHP-ESKSSESS--G
VQT----VSKP-------------------------------------------------
---------------------------SFSKTSSQDDPGASS-LLQLD-STKDTPS----
-----SSILKKRTEGIDQVSLGLK-HPSSSKVN-S-VNPKKPKTNT---SVSEASPSSSS
SSSNSPSEA------------------------SSQVIVA-NENTSSIQSE---------
-----TGAPSLRSCPKCSVKFSFLDPLKCHMKNCCPDMINNFLETL-KSEHSRAENKANI
DADK-EKLIMLVSDFYYGRH----------------EGAIE---EDPKTHTTFKCFSCSK
VLKNNIRFMNHMKHHLEHEKQNS-ESWENHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQN-KGIHRCPKCRLQFLTCKEKTDH-KLEHR
TFIKPKELEGLPPGTKVTIRASFGSVQSRSSSP---PSSPIPS-TSLQVSSPTS-KSTTT
K-----STTAKS--TTISKAQTVLST------------------------TISKPNTSKS
GTGATKSK--AKPSYKQK----------KQRTRKNKFSIALKNLRCH-------------
----HGIHT----CMECHSKIKDFSSHFSTHINCDFCKYTTNCNKAFTNH-MSSHSDHPS
KQFYIFKKHSRA-IRG-ITLVC-LKCDFLADTSGLDRMAKHLNQRKTHSCQVVIENVT--
ERTSESTSE---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGNK
PFQ---------LKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEITSSKPAI-SN--ILNRVTPSS--Y-SRGIKNGALG--RGVT
PAFKPTNQ-----------------HFTNQTSNPVTASP----VNFQM-ESRSSASSV-I
VQP----LSKP-------------------------------------------------
---------------------------GFIMNSSRVVS-NSS-ELLFD-LTQDTAV---A
---HYQGGPALSIAGINESSFLSK-RPSTCEV--NSAISKKPKPSEGVSGTSSS---ATF
SSINSNSLT------------------------SPQEVPSKGINTSPNQSK---------
-----TATPFPKACPKCNIHFNLLDPLRNHMKXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXX----XXXXXXXXXX----------------XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXFMNHMKHHLELEKQNS-ESWDNHTTCQHCYRQYPTPFQLQCHIESTHTPH-DF
STICKICELSFETEHVLLQHMKDN HKPGEMP YICQVCNYRSS-SFSDVEIHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQX-XXXXXXXXXXXXXXXXXX-XXDHTQHHR
IIANLMLVTG--------TQASVGAPPSGSSFT----PSISASTSTLQLSPART-KNLTA
K-----NPTKSIINKPSATKFNA----------------------------------SKP
NGSKSKCK--PKISNVQKKQNT-----LASSNKKSKVNTALRNLRYR-------------
----RGVHE----CIECSSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLC
IPT----FEHLSEVRNEASTEEQ------EPVSEEISRL------RMAEGETETAKSESE
QDTISSEEGKNGCDENSFEAS-SVTKSEESITVSLKTNDACHPDQESGSKEIISDDSI--
-KDEDKVEKEKQIELVRQETE-LKLCQ-NSENVDSCDQIKDHN-SGETKRSSKN-IKALR
LTTG---DDVSIDQFLRKRDGSESVSSDVSEQGSVHLEPLTPSEVLEYQASEIFQKGGGD
--SSAKPDEVTCYQTADMPRGNSLNTTETAVDLVDEEGRS---

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIQETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYDHLR--KDTA
RKLQPK-------------------SHETVTSEAVTVL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYRNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHHPV--STALSVGGINESPRVSK-QLSTFEV--NSINPKRAKLRDGIIEG---NSSAS-
--------------------FPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQRN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSAHQCSKCRLQFLTFKEKMEHKTQYHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------MDSH----S-RKNRKV---------QEF------II
FLR---------TDYNSKMAELFMECEEEEL-EPWQKKVEEARN----E-----------
----DDDDELIFV---GEISSSKPAI-SN--ILNRGNSSS--S-SKGMKNDSLS--SGIP
GLFKSTSQ-----------------HYKDPASNP-----VTALPRFHP-ESKSSQSSA-V
VQN----TSKP-------------------------------------------------
---------------------------VSISENAQLVQ----------------------
-------------------------RHTRY-----QVKIMNSHTIE---SVSEINPSSSL
SLNNSPSEA------------------------SSQVMVST-------------------
-----TTVPFLRSCPKCNIQFSLLDPLKYHMKRCCPDMINNLMESV-KTELSCAEDKTNT
GSEK-GKLIMLVSDFYYGRH----------------EGAME---EEPKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKTDH-KTQHR
TFIKPKELEGLPPGTKVTIRASFGPLQPRPSST---PSNCAPSTSSLQVLPPKS-KSTTA
K-----NLTKSNASKSKTSKPNAAASAAS------------------------KPNTSKQ
SGGGVTTKSKAKHSYKQK----------RQRNRKNKISIALKNLRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMMSSHSNHPS
KRFYIFKKHSGI-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVVIENVS--
ESTSTSEPTSE-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPFVLCDEEQE-P-------------SQAPDEDAELIFVG
VEHVNDDSELIFV---GMSSNSKP-ANSN--ILNRVTPGS--R-LKRKR-NRLR--TATT
QRPQPSQPS----------------GPATPSSDTVIVL-----PASPA-ESRSTDSPI-I
IEP----LSEP-------------------------------------------------
---------------------------DYRSNSPQVVPDSSP-EGSPL-VTVS----SSQ
HSPPV--RAALSVGDLNESSYVSK-CHSTSGA--NAVNPQRPDLIIEIVEE---PSPAS-
--------------------APSGTSQTSN---PQPSTPASHVPQSLNPVV---------
-----NGEHSVHNSPTNV---------HPGQ-----------ENGLAPGGFSSLASQE-T
PDPKKGSLTLLLSDLYYGQH----------------KGDG---QPEQKTHTIFKCPSCLK
AL-KNVKFMNHTKHHVELERQGN-DGWESHTTCLHCYRQFTSPFQLECHVDRVHTAP-NP
ATVCKICDLSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSS-SFSDVDAHFRKCHVNTK
NLLCPFCLKIFKTGTPYMC-----HYRGHWE-KNGHQCSKCRLQFLTFKEKMEHKTRCHQ
IFKRPKHLEGLPPDTKVVIQVSAEPVESESVKV---ASITVS-TTDWEPSSPKS-PGRPS
K-----RSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
L---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGGNSSTIL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLT-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITGVC-LNCDFLSDVSGLDNMATHLSQHTTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIARP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSTTKSEESL-TVSDKENETCLADQETGSKSIFSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
-------------------------------------------------------MDDDK
PFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQN----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EILRTASQ-----------------RCRDPPSNP-----VAASPRFHL-VSKSSQSSV-T
VEN----AS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-ILLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVIPKKPKTSE---DVPQLNPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----DGADYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCGED--KT
DSEM-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETERILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKLPTA---PSGCAPGTSFLQVTPPTS-QNTTA
K-----NTRKSNASRSKTSKPRATTSTA------------------------SKANTSKP
RGRIAKSK--AKPSYKQK----------RQRNRKNKMSLALKNIRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTTGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------MDNNNN
TFQ---------PKXXXXXXXXXXXXXXXXX-XXXXX------------------XXXXX
XX--XXXXXXXXX---XXXXXXXX-XXXX--ILNRGTPSS--S-SKGLKNETLG--QGG-
-AVKAASQ-----------------QNKDPTSSRAAAV----LPRFHP-ESKSLHSPV-S
AQN----MSDP-------------------------------------------------
---------------------------DFTKNLSQVESDDSS-DLLFD-LTQDTIPLS--
--QES--SEIYIEALDQSMPF-LK-RPSSSKR--NSVSPKKPKISDDLSEK---SSSLSL
PSSPS--VTSSSSILSK------------------------SSDSSSVQCK---------
-----TTMPLQRSCPKCNIQFNLLDPLKYHMKRCCPDMLSKF--SSVSLDLPS-TEKKYM
LSTEKGKLVMLVGDFYYGKH----------------EXXX---XXXXXXXXXXXXXXXXX
XXXXXXXFMNHMKHHLEFEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFESEHTLLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVENHFRACHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKTDHKAQ-HR
TFIKPKELEGLPPGTKKYKTTKPQTSKPCAS------------TSTV--S----------
-----------------------------------------------------KTKATKG
GRSTYKRK--TKTSNKQK----------KQHNRMNKISVALKKLRCR-------------
----RGIHK----CIECHTKIKDFASHFSVYTHCNFCKYHTNCNKAFMNHMMSSHSDHPS
KRYYIFKKHSGA-LXX-XXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXX--XYFW--K-------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCMLCEE-EQVPEPQQNVEDTKQ----VD-EDAELIFVG
VEHVNDDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--C-SRRKKYGHLR--KGTT
HKLQPV-------------------SYVTPVSEAVTDL-----PVSES-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNNSPQVVPDSSS-ELCS-PLITF----TSS
LQHPG--GAALSVGGMNQSTCISK-RLSTAEV--NDINPKRPKLSDGIIGG---HASAL-
--------------------SPSGNFHTMT---TQQSTLSNNVHTSLSHVQ---------
-----NGAPFPTAFPKDSVHFKPISP--VK------------ENKLTETDLLSLASQNQI
VDSKKGSLVILLHDFYYGQY----------------KGDS---QPEQKTHTTFKCLSCLK
VLK-NVKFMNHMKHHLELEKQRA-DSWENHTTCQHCHRQFPTPFQLQCHIESVHTTQ-EP
SAVCKICELSFKTDQVLLQHMKDNHKPGEMPYVCQVCNYRSS-AFADVEMHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWE-KSVHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSLGPLQPGSVEL---ASVTVS-TSDSEPSPPRS-KSRIP
K-----KPR---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------KLDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGLKNGALN--RGFA
TSFKPTSQ-----------------RFPNPASNPVAALP----VSFHP-EPRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYLTNSPRVLSNNSS-ELLFD-LTQDTGL---S
---HYQGGPALSIAGLNESSFSSK-RLSGSDI--SSVNPKKPKASDSIPGTDASSVVP--
--EKPPSVS------------------------SLQVVTSQGVNCSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKNHMTYCCPDMINN-FWGLSKIEISNTANEAKT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTLL-DF
SSKFQL---PFSVR-----------------C----------------------------
-----SCLRLLKLKQEIDFEFGGLLTPPASK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLTSGSSTT----PFISASTSTLQLSPPRT-ENVTS
K-----NPTKLNTSTPNTAVSDSSKP--N---------------------------ESKP
NGSKSKNK--SKVCTTQKRQS-----TVANSNRKSQVNTALRNLRLR-------------
----RGVHE----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLIEKGILK
TEAPTKGQESVSK--------------------------------------------VNK
QDKAPSSEEDVGCDASVCETPAA-ANCEGNVTISDTENES-------RSKNIFSHDSD--
-VGADNMGKEEQTQHTCQELE-LKVHQ-HSEK---------HD-SPADELSSET-GQDLQ
LT-S---GDISIDEFLRQRDKPEPVSSDASEQDSVRLEPLTPSELLEHEATEILHKGDDS
--SASASDT-VSDLTGGLMSPGGH-GAETAVDLETGKKESEVM

------------------------------------------------------------
-------------------------------------------------------MDDGK
TFQP---------KNIPKMTELFMECEEEEL-EPWQKKVEKTQD----E-----------
-----DDDELIFV---REISSSKPAI-SN--ILNRSHSSS--S-SKRIKNEPVS--PGIP
E------Q-----------------RYRDPPSNA-----VAALSVFHP-ESKSSQSSV-T
VEN----ESNK-------------------------------------------------
---------------------------SDVTEHSQVELNNSS-PLLFD-STQES-L---S
---ASQDIPAIFREGMKNASYVLK-HPSTSKV--NSVTPKKPKTSE---DVPEINPSTSL
PLTDSPPAT------------------------PSHLRLAKGTNTSP-PYD---------
-----AEALYLRACPKCKVQFNLLDPLKHHMKHCCPNMITTFLGEIIKSERPRAEDKNET
DPET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQRCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVIKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-QAQHR
TFVKPKELEGLPPGTKVTIRASLGPHQSKLPTT---PSGYTPGTSFLQVTPPTS-QNSTA
E-----NPRKSAASKSKTSRPH------------------------ATTSTASKANTSKP
RGRTAKCK--TKPSYKQK----------RQRNRKNKMTLALKNLRCL-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KQFCIFKKHSGT-LSG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVF--
KSTSTSEPTSDCPLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSDLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGRPTLSIAGMNESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSVAL
PSVKSPSVT------------------------SSQAMSAKGANTTSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGVHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NTAKSNTSKPNTI--KS---------------------------NTSKPNTSKP
NGSKSKYK--SKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----LGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITVVC-LNCDFLSDVSGLDNMATHLSQHETHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------ESVSKEITRP------NMAERETETSNSESK
QDKTASSEEKNECNANSFEGSSTTKGEESI-TVSDKENDTCLADQETGSKKIFSGDSN--
-IGADKMEKEKQIQHVCQEME-LKMCQ-SSQNVISCDQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSTDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSPQTEEVVSDQTDNIPGGNNPSTTEATVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
---------------NSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNSTSNPVAASP----VNFHP-ESRSSDSSV-I
VQP----LSKP-------------------------------------------------
---------------------------GYIMNSSRVASSNSS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGVNESSFLSK-RPS-SEV--NSINPKKPKPSE---GVSGANSSAVF
PSVKSLSVT------------------------SPQAMSSKGITSSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLT-KTEFLSTANKNQT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSTT---PSISA-NTSTLQLSPPRT-KNITA
K-----NPTKSNTSKPNTT--KS---------------------------NASKPNASKP
NGSKSKFK--SKVSNMQKKQNTL-----ASSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEVKDFANHFPTYVHCSSCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFLADVTGLDNMATHLSQHETHTCQVVVEKVSVC
IPTSEHL--SE--LKNEAPAKEQ------EPVSEEIARP------NMAEE-TETSNSESK
QDKA-SEEEKIGCDANSFEVSSATKS-EESIIVSHKENDTCLEDKETGSKNIFSYDSN--
-IGED-------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCLLREELDPEPEPQKSAKETKQ----MDDEDTELIFVG
VEHVNKDAELIFV---GVTSNAKP-VVSN--ILNRVTPGS--G-SRRKKCGRLR--KNTA
HRLQPT-------------------SHVASPSETVTVL-----SDSPS-ESRSTDSPI-I
IEP----LPEP-------------------------------------------------
---------------------------DCKNSSSQVVPSSSS-QLGSP-LVAL----TSS
LHHPV--KTALSVGEMNESQCVSK-RCSTSEV--NIINSKSPKLSNGIVGG---ISSAL-
--------------------SASDISRTVN---LQQSIPSNDVHTSLSHVQ---------
-----NIAPFPAAFPKDSVHFRPTNVNPDM------------ENGLAK--IASPTSQNKT
FDPKTGTLILLLSDFYYGQH----------------KGDE---QPEQKTHSTFKCLSCLK
VLK-NVKFMNHMKHHFELEKQRG-DSWENHTTCQHCYRQFPTPFQLQRHIASVHTTQEEP
FAICKICELSFETDQVLLQHMKDNHKPGEMPYVCQLCNYRSS-AFGDVETHFRICHENTK
NLLCLFCLKIFKTAAPYVC-----HYRRHWA-KSIHQCSKCRLQFLTFKEKMEHKTRCHQ
MFKKPEQLEGLPPETKIVIQVSLGPSQPDSVKV---ASITVS-TIEPEPSPRKS-KSRIP
K-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCLLREELDPEPEPQKSAKETKQ----MDDEDTELIFVG
VEHVNEDAELIFV---GVTSNAKP-VVSN--ILNRVTPGS--G-SRRKKCGRLR--KNTA
HRLQPT-------------------SHVASPSETVTVL-----SDSPS-ESRSTDSPI-I
IEP----LPEP-------------------------------------------------
---------------------------DCKNSSSQVVPSSSS-QLGSP-LVAL----TSS
LHHPV--KTALSVGEMNESQCVSK-RCSTSEV--NIINSKSPKLSNGIVGG---ISSAL-
--------------------SASDISRTVN---LQQSIPSNDVHTSLSHVQ---------
-----NIAPFPAAFPKDSVHFRPTNVNPDM------------ENGLAK--IASPTSQNKT
FDPKTGTLILLLSDFYYGQH----------------KGDE---QPEQKTHSTFKCLSCLK
VLK-NVKFMNHMKHHFELEKQRG-DSWENHTTCQHCYRQFPTPFQLQRHIASVHTTQEEP
FAVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQLCNYRSS-AFGDVETHFRICHENTK
NLLCLFCLKIFKTAAPYVC-----HYRRHWA-KSIHQCSKCRLQFLTFKEKMEHKTRCHQ
MFKKPEQLEGLPPETKIVIQVSLGPSQPDSVKV---ASITVS-TIEPEPSPRKS-KSRIP
K-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNK
PFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSE---NVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDKNKT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKLPTA---PSGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNAGRSKTRKPHAPTSTAS------------------------KAHTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNLRCR-------------
----RGIHK--CI--ECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMR-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
A---------RKSLHNSKMAELFMECEEEEL-EPWQKKVKEVDD----D-----------
---D-DDDEPIFV---GEIASSKPAI-SN--ILNRVNPGL--Y-SRGIKNGALSR--GVT
AAFKPTSQ-----------------HYTNSTSNPVSASP----VNFHP-ESRPSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNPSQAVSNNSS-ELLFD-LTQDTGL---S
---PYQGGPALSIAGVNESSFISK-RPSASEG--NSVNPKKPKPSE---SVSATDSSAVF
PSINSPSQT------------------------SSQAMPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVE-DFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKLDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVAPLQSGSSPT---PSISA-STSTLQLSPPRT-KNITA
K-----NPTKLNTSKPNTP--KS---------------------------NASKSNGSKP
NGNKSKYK--SKTSNVQKKQSTL-----ANSNKKSKVNTALRNLRYH-------------
----RGVHK----CIECCSEIKDFANNFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKRSED-LRG-ITLVC-LNCDFLADVSGLDNMAKHLSQHETHTCHIVTEKVSVC
IPTSEHL--SD--VQIHFLM------------NLYFSVSKMKLHQK-KNMDVMQIYLKAH
QQHKGKKT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQRKVEETQV----E-----------
----DDDDELIFV---GEISSSKPAI-SN--ILNRSNTSS--T-SKAIKSEPL----RIS
DIFKPTSQ-----------------HYRDPASNP-----VATLTRFHP-GSKSSQSSS-I
VQN----MSKS-------------------------------------------------
---------------------------DSSKNSSQEESDNSS-VSLFD-SSQDT-I---P
---LSTGVD--------ETSFGLK-RS-ASKI--NSVNPKKPKTSG---SISEINLSSSL
SLSNS-SEE------------------------SSQVMVSPGSNTSSTEQK---------
-----TEEFVLRSCPKCDIQLNHLELLKYHMKRCCPDMLNNFIGTV-KMEPSSAEGTTNT
GSEK-EKLIMLVSDFYYGKH----------------DGSLE---EEPKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRTSHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCSKCRLQFLTCKEKTDH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPPQSKPPGT---PSNSAPSSSSLQVLPLES-KNTTA
K-----NLTKS-----KTTKPQATVSSAD------------------------TPNTSKP
SGGTTKYK--AKFSCKQK----------RQRNRKSKLNLALTNLRCL-------------
----RGIYK----CIECRTKIKDFANHFPIFANCNFCKYSTNCNKAFVSHMISVHNQHAP
RTFSL---SSFF-HRG-ITLVC-LKCDFVTDSSGLDLMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPTSLSKFFI--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNVKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQPT-------------------SHETLTSEAVIDL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNSSPQVVPNNSS-ELPSPLV-TF----TGS
LHHPV--SAALSVGGINESPHVSK-RLSTFEV--NSINSKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---TQQSTPSNNVHTSLSHVH---------
-----NGAA----FPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGRPTLSIAGMNESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSATL
PSVKSPSVT------------------------SSQAMSAKGANTTSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----TPAKSSTSKPNTI--KS---------------------------NTSKPNTSKP
NGSKSKYK--SKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----LGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHETHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------KPVSKEITRP------NMAERETETSNSESK
RDKAA-SEEKNECNANSFEGSSTTKGEESI-TVSDKENDTCLADQETGSKKIFSGDSN--
-IGADKVEKEKQIQHVCQEME-LKMCQ-SSENVILCDQIKDHH-SREARFSSKN-IKDLR
LTS----DNVSTDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSPQTEEVVSDQTNNIPGGNNPSTTEATVDLADEKERSRN-

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVAASP----VNFHP-ESRSSDSSV-I
VQP----LSKP-------------------------------------------------
---------------------------GCKMSSSQVVSNNSP-QLLFD-LTQDTGL---S
---RYQGAPALSIAGMNESSFVSK-RPSASEM--NSVNPKKPKPSE---GISGASSSMAF
SSLTPASMA------------------------SPQAVPSKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTDFSSTTNKNKT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVEAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFMKPKQLEGLPPGTKVTIRASVGPLQSGSLPT---PSISA-STSTLQLSPPRT-KNITA
K-----SPIKSNTNKPNAA--KP---------------------------NASKPNASKP
NGSKSKCK--PKISNVQKKQNTL-----TGSNKKSKVNTALRNLRYR-------------
----RGVYN----CIECCSEIKDFANHFPTYVHCSVCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITIVC-LNCDFVTDVSGLDSMATHLSQRETHTCQVIMKNVSVC
IPTSEHL--SE--LKNEAPSVEQ------EPVSEVNFCF------TSYPKDNKWLYFFSK
HDKASPEEEKNRCDSSSFEGSSVTKS-EESITVSHRENDACLIVQETSSKKTFGYDSN--
-TGEDKVEKEKQIELVCQEAE-SKMCQ-SSENTVTRDQVKGHG-SGEARLSSKN-IKDLR
LTS----GDVSIDQFLRKRDEPESAISDVSEPGRIHLEPLTPSEVLEYEATEIFQKGGGD
--PSAKTDEAVSDQAGDVLREGSPTMTETTADLAGEKE-----

------------------------------------------------------------
------------------------------------------------------------
------------------MERPCMLREE-EQEPEVRKREGETKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VVSN--ILNRDTPGS--C-SRRKRYGHFR--KGNA
HKSQPV-------------------SHVTPTSEAKTVL-----PVSDS-EPRSPESPI-I
TEP----PSQA-------------------------------------------------
---------------------------DYKNISPQIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RLSTCET--NSRNPRRPKLSDGIIGE---HSLGF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSLSHAQ---------
-----NGEPCPTPFPKDSVHCKPVRP--LG------------ENGLTKTDFPSLASPDKI
VDPTEGNLIVLLRDFYYGEH----------------IGVG---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFADVDAHFRACHGNTK
NLLCPFCLKIFKTATAYRR-----HHRGHWE-KSFHQCSNVGYSF---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNN
PFQ---------PKSNPKMAELFMECEEEEL-EPWQKKVEEIKD----E-----------
----DD-DELIFV---GEILSSKPAI-SN--ILNRGNSSS--S-SKGIKSEALS--PGIP
DVFKPTSQ-----------------HYKDPTSSP-----VAALPRFHP-ESKSSHSSV-I
VQN----ASKP-------------------------------------------------
---------------------------DFTKNSSQAESDDSS-VLLFD-LTQDT-I---P
---LSQDRPAVFIEGMDQTSFVLK-RPSTSKV--NSVNSKKPKTSE---DVSEINPSASL
SVINSPSGT------------------------SSQALLSKGTNTSSTQYK---------
-----TGAPFLRACPKCNVQFNLLDPLKYHMKRCCPDMVNNFLGII-KAELSSAENKNKT
SSEK-GKLIMLVSDFYYGRH----------------EGAAE---EEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNT-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVEAHFRASHENTK
NLLCPFCLKVSRMATPYMN-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDH-KTQHR
TFIKPKELEGLPPGTKVTIRASLGPHQSKPSTT---PSSCTPSTSSLQVSPPKS-KNTTA
K-----NPTKSSASKSKTSKSHATASTAN------------------------KPRTRKP
SGGISKCK--PKPSSKQK----------RQRNRKNKISIALKNLRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMMSFHSSHPS
KRFYIFKKHSGT-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPTSDRLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MGDIFL-CKKVESP---KKNLRESKQ--REEDDEDPDLIYVG
VEHVHRDAEILFV---GMISNSKP-VVSN--ILNRVTPGS--N-SRRKK-GHFR--QYPA
HVSQPA-------------------NHVTS--MAKAIM-----PVSLS-EGRSTDSPV-T
MKS----SSEP-------------------------------------------------
---------------------------GYKMSSPQVVSPDSS-DSLPA-GT---------
-QRLV--GAMVSGGGRNESSPDSK-RLSTSDI--NSRDSKRVKLRDGIPGV---PSLAV-
--------------------VPSDISSTIS---TNTPSQG--VCNSSNHVQ---------
-----NGVTFPWADANGKAHFNLTNPERANE------------SGLAMTDISSLASQNKT
FDPKKENPVVLLSNFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NIKFMNHMKHHLEFEKQRN-DSWEDHTTCQHCHRQFPTPFQLQCHIDSVHIAM-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCLFCLKLFKTAIPYMN-----HCWRHSR-RRVLQCSKCRLQFLTLKEEIEHKTKDHQ
TFKKPEQLQGLPRETKVIIQTSVQP---GSSGM---ASVIV-------------------
--------------------SNT-----------------------------------DP
QSSSVKT-----------------------K-KTAMNTRDSRL-----------------
---------------PCSKDSS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEPPCMLFEE-EQEPELQKSIEETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GMTSNSKP-VVSN--ILNRVTPGS--C-SRRKKYGQFR--RDNA
HKFQPI-------------------SCVTPSSEAVTFL-----AVSDS-ETRSGDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNYSPQIVPDNSS-ELCS-PLITF----TSS
LQHPL--RTALSAGDMNKS-QVSK-RLSASET--NSTNPKRCKLSDGIIGG---HSLAL-
--------------------SSSGIFQTVT---SQQSTPSNSIHTSLSHVQ---------
-----DGEPFPL---KDIVHSKPINP--FG------------ENGPAKTAFSSLAGQNKT
VDPKKENLIMLLHDFYYGQH----------------IGDG-----------------CLK
VLK-NVKFMNHMKHHLELEKQRG-DSWKNHTTCQHCHRQFPTPFQLQCHIESVHTSQ-GP
SPVCKICELSFETDQVLLEHMKDNHKPGEMPYVCQVCNYRSS-AFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWE-KSVHQCSKCRLQFLTFKEKMEHKTQYHQ
MFKKPKQLEGLPPETKVVIQVSLGPLQPGSVEV---ASITVS-TSDSEPSPPRS-KSRIS
K-----KPR---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDKDN
SVQEKGLFLSSWKLDNSKMAELFMECEEEEL-EPWQQKVEESQS----KD----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLKNGSFN--PAIS
NIFKPTSQ-----------------HYRNPSSNA-----LVALPSFHP-ALKSSESS--D
GQT----VSKL-------------------------------------------------
---------------------------NFTKTSPQEDSGACS-VSQSD-STQDIPS----
-----SNILQPRT-GVD-QTLGLK-HPSTSKVN-S-VNPKKPKTSA---SISETRPCSSS
SLRTSP---------------------------SSQTVLS-NMNTSSVQSA---------
-----PGSSSLRSCPKCNVKFRLLDPLKCHMKRCCPDMINKFLETL-KSENSKAVSKATI
DSDK-EKLIMLVSDFYYGRH----------------EGTIE---ESQKTHTTFKCFSCTK
VLKNNIRFMNHMKHHLELEKQNN-ETWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKVSRMATPYMN-----HYMRHQK-KGIYRCPKCRLQFLTSKEKTEH-KLEHR
TFIKPKELEGLPPGTKVIIRASLGSSQSRASSP---PSSTIPS-TSLQLSVPKS-KSTT-
----TKNNSKVSANKATTTSPQTIAT------------------------TTGKPSASKP
GTGTTKSK--AKPSYKQK----------RQRTRKNKFSIDLKNLRCH-------------
----QGSHT----CIECRSKIKDFSSHFSTHINCDFCKYTTNCNKAFTNH-MSSHNDHPS
KQLYIFKKQSRA-RRG-ITLVC-LKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVT--
ERAVTSESASDGLFK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDKDN
SVQEKGFFLSSWKLDNSKMAELFMECEEEEL-EPWQQKVEESQN----KD----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLKNGSFN--PAIS
NIFKPTSQ-----------------HYRNPSSNP-----LVALPSFHP-ALKSSESS--D
GQI----VSKP-------------------------------------------------
---------------------------NFTKTSSQDDSGASS-VLQLD-STKDIPS----
-----SNILQPST-GVD-QTLGLK-HPSTSKVN-S-VNPKKPKTNA---SISETSPCSSS
SLQKSPSEA------------------------SAQVVLS-NMNTSSIQSA---------
-----PGSSSLRSCPKCNVKFSLLDPLKCHMKRCCPDMINNFLETL-KSENSKAVNKAIT
DSDK-EKLIMLVSDFYYGRH----------------EGAIE---EGQKTHTTFKCFSCTK
VLKNNIRFMNHMKHHLELEKQNN-ETWESHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKVSRMATPYMN-----HYMRHQK-KGIYRCPKCRLQFLTSKEKTEH-KLEHC
TFIKPKELEGLPPGTKVTIRASLGSSQSRSSSP---PSSTIPS-TSLQLSVPKS-KSTT-
----TKNNSKVSANKATTTSPQTIST------------------------TTGKPSASKP
GPGTTKSK--AKPSYKQK----------RQRTRKNKFSIDLKNLRCY-------------
----QGSHT----CIECHSKIKDFSSHFSTHINCDFCKYTTNCNKAFTNH-MSSHNDHPS
KQLYIFKKHSRA-LRG-ITLVC-LKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVT--
EKTETSESTSDGLFK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDK
RFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---REISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RCRDPPSDP-----VAA------------------
------------------------------------------------------------
---------------------------SDFTKNSQVGSDNSS-VLLFG-STQES-L---P
---PSQDIPAIFREGMKNTSCVLK-HPSTSKV--NSVTPKKPKISE---DVPQINPSTSL
PLTGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGADYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCGEDN-KT
DSET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETERILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPHQSKLPTA---PSGCAPGTSFLQVTPPTS-QNTTA
K-----NPRKSNASRSKTSKPHATTSTAS------------------------KANTSKP
RRRIAKSK--AKPSYKQK----------RQRNRKNKMSLALKNLRCR-------------
----WGIHK----CIECHSKIKDFASHFSIYIHCSLCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPTSGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------M-G-DS
S---------FQPKDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGIKNGILNR--GFT
ASFKPTSQ-----------------RCPNSASNPVAALP----VNFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYVTNSPRVLSSNPS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGLNETSFLSK-RPSGSDI--SSVNPKKPKPNE---NISGTDASSVV
SSEKSPSVM------------------------SLQVVPSQGTNCSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKNHMTYCCPDMINNFLGLT-KTDNLNSANEAKT
LDSEKGKLIMLVNDFYYGKY----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSEVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVAPLQSGSSVT---PSISA-STSTLQLSPPRT-ENVTA
K-----NHVKLNTSTPNTT--IS---------------------------DPSKTNEIKS
NGSKSKNR--SKVSNMQKKQSTL-----SNSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRYCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLVEKVSVC
IPTSERL--SE--LKTEAPTKGQ------ESVSKETAR------HSTAEREPGASHSESK
QDKAPPSEDDTGRDASVCEAAAAAN-RERNVTASDTED-------VRTSNDVLSRGPE--
-VGTDNMEKEEQAHHTCQEME-LKRDQ-SSESTD--DQSKEHS-PTEAELSSEI-SQDLQ
LTP----EGVGLGQCLRQGEEPESVNSDASEQDSVRLEPLTPSEVLEFEATEVCHSGED-
--PSASTSDAVSGGTGGSPGGSSPRRAESAADLAGGQEGS---

------------------------------------------------------------
------------------------------------------------------------
------------------MERPCMLREE-EQEPEVRKREGENKQ----VGDDDDELILVG
VEDVNEDADVIFV---GMTSASKP-VVSN--ILNRDTPGS--C-SRRNRYGHFR--KGNA
HKLQPV-------------------SHVTPTSEAKTVL-----PVSDS-EPRSPESPI-I
TEP----PS---------------------------------------------------
----------------------------------QIVPNCFSKELCSS-LITF----TSS
CQHPV--ERAVSAGDMNKSPHVSK-RRSTCET--NSRNPRRPKL-------------SF-
--------------------SPSGIFHT---VPTQQST-PDRVHTSL-------------
-------KPCPTPFPKDSVHCKPVRP--LG------------ENGLTKTDFPSLASPDKI
VDPTEGNLIVLLRDFYYGEH----------------IGVG---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKHHLELERQRG-DSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-GP
SAVCQICELSFETDQVLLEHMKDNHKPGEMPYVCQVCSYRSS-FFADVDAHFPSMPW---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MGDNP
F----------QPKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVAASP----VNFHP-ESRSSDSSV-I
VQP----LSKP-------------------------------------------------
---------------------------GYVTNSSRVVSNNSS-ELLFD-LTQDTGS---S
---HYQGGPTLSIPGMNESSFLSK-RPSTSEV--NSVNPKKPKPSD---GISGLNSSAVF
PSVKSLSVT------------------------SPQAMSSKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNKT
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSPT---PSISA-STSTLQLSPPRT-KNITA
K-----NPTKSNTSKPNTT--KS---------------------------NTSKPNASKP
NGSKSKYK--SKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFVADVSGLDNMATHLSQHETHTCQVVIEKVSVC
IPTSEHL--SE--LKNEAPTKEQ------EPVSEEIARP------NMAEGEKETSNSESK
QDKAS-EEEKNGCDTNSFEGSLATKS-EESITVSNKENDTCLEDQKTGLKNIFSHDSN--
-IDADKVEKEKQIEHICQKTE-LKMCQ-SSGNIISCDQIEDSN-SSETRFSSKN-IKDLR
LTS----ADVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDSVPGENSPSTKETTVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQQKVAEIEN----KD----------
-D----DDELIFV---GEISSSKPAI-SN--ILNRCSPGS--S-SKGLRSDSFS--PAFA
NIFKPTSQ-----------------QYRNPSPNP-----VTALPKFHT-ESRSSESS--G
FHA----VSKP-------------------------------------------------
---------------------------SFSKTSSQDDPGASS-VLQLD-STIDTPS----
-----SSILKKSTEGIDQTSLGLK-HPSTSKDN-S-VNPKKPKTNA---SVSETTPSSSS
----SPSSA------------------------FTQVVVS-NEYTSSIQSK---------
-----TGASSLTCCPKCKVKFSYLDPLKYHMKRCCPDMIDKFMEK-----HSGDEKKSRI
TSEK-DKLIMLVGDFYYGRY----------------DGFIE---EELKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLEHEKQNS-ESWESHTTCQHCFRQYPNPFQLQCHIESTHTPH-GF
STICKICELSFETEHLLLQHMKDTHKPGEMPYICQICQFRSS-IFSDVETHFKLTHENTK
NLLCPFCLKVSRMATPYVN-----HYVKHQN-KGVHRCPKCRLQFLTSKEKADH-KLEHR
TFIKPKDLEGLPSGTKVTIRASLGSVQSRPPSP---PPSSIPS-TSLQVSTSES-TTTKS
N-----SKAPANKSKSKISTPQVVLT------------------------AVSKPSTSKL
GPSATKSK--A----KHK----------KQRTRKDKFSLALKNMRCQ-------------
----QGIHT----CIECHSKIKDFPSHFSAVINCDFCKYTTNCNKAFTNH-MSSHNDHPS
KRFCIHKKHSRP-HRG-ITLVC-LKCDFLADTSGLDHMAKHLNQRKTHTCQVVIENVI--
ESTSTSESTSDGLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPFVLCDEEQE-P-------------SQAPDEDAELIFVG
VEHVNDDSELIFV---GMSSNSKP-ANSN--ILNRVTPGS--R-LKRKR-NRLR--TATT
QRPQPSQPS----------------GPATPSSDTVIVL-----PASPA-ESRSTDSPI-I
IEP----LSEP-------------------------------------------------
---------------------------DYRSNSPQVVPDSSP-EGSPL-VTVS----SSQ
HSPPV--RAALSVGDLNESSYVSK-CHSTSG---------RPDLIIEIVEE---PSPAS-
--------------------APSGTSQTSN---PQPSTPASHVPQSLNPVV---------
-----NGEHSVHNSPTNV---------HPGQ-----------ENGLAPGGFSSLASQE-T
PDPKKGSLTLLLSDLYYGQH----------------KGDG---QPEQKTHTIFKCPSCLK
AL-KNVKFMNHTKHHVELERQGN-DGWESHTTCLHCYRQFTSPFQLES-----PPAP-NP
ATVCKICDLSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSS-SFSDVDAHFRKCHVNTK
NLLCPFCLKIFKTGTPYMC-----HYRGHWE-KNGHQCSKCRLQFLTFKEKMEHKTRCHQ
IFKRPKHLEGLPPDTKVVIQVSAEPVESESVKV---ASITVS-TTDWEPSSPKS-PGRPS
K-----RSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQPT-------------------SRETLTSEAVTDL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYKNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHQPV--SAALSVGGINESPHISK-RLSTFEV--NSINPKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELTKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTANSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
DKLQPT-------------------SHETLTSEAVTDL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYTNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHHPV--SAALSVGGINEGPHVSK-RLSTFEV--NSINPKRAKLRDGIMEG---YSSAS-
--------------------SPSDTFHTMN---AQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQKN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSTHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVEV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMSESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSAVL
PSVKSPSVI------------------------SSQAMLAKGVNTQSLFVR---------
-----LV----------------FFFFFFFFQYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKSNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE---------------------------P------NMAERETETSNSESK
QDKAASSKEKNGCNANSFEGSSTTKSEESI-TVSDKENETCLADQETGSKNIVSCDSN--
-IGADKVEKKKQIQHVCPEME-LKMCQ-SSENIILSDQIKDHN-SSEARFSSKN-IKDLR
LAS----DNVSIDQFLRKRHEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLEDEKERS---

------------------------------------------------------------
-------------------------------------------------------MD-DD
PSQ---------PKXXXXXXXXXXXXXXXXX-XXXXX----XXX----X-----------
----XXXXXXXXXXXXXXXXXXXXXX-XX--ILNRGNPSS--S-SKGIKNETVS--PGVT
DVFKPTSQ-----------------HYKDPTAYP-----VVALPRFRP-ESKSSQSSD-I
VQN----VSKP-------------------------------------------------
---------------------------DFTKNSSQDESDDSS-DLLFD-LTQDT-I---P
---LSQDGSTVYVEGLGETLPIKK-RSTASKV--KSVNPKKPKTGE---SVSEINPCSSL
SLINSPSVA------------------------SSHVMISKXXXXXXXXXX---------
-----XXXXXXXX-XXXXXXXXXXXXXXXXXXRCCPDMVNTFLDMI-KVELSSHENRNKT
GAEK-GKLIMLVSDFYYGRH----------------EGAVD---DEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWESHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHTLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVEAHFRASHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCTKCRLQFLTCKEKLDH-KTQHR
TFIKPKELEGLPP---VTIRASIGPLHSRPSTTS--P-RSTPSTSFLQVSPPKS-KSTTA
K-----SPAKSNASKSKTGKLSASTSTAN------------------------KANPSKQ
GRAIPKYK--AKASYKQK----------KQRNRKNKISIALKNLRCR-------------
----RGVHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFINHMVXXXXXXXX
XXXXXXXXXXXX-XXG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVIIEKVP--
ESTSTSEPTSDRLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPCVLCEE-EQDPEPQ-NIKETKQ----IDDEDAELIFVG
VEHVNEDAELIFV---GVSSNSKP-VVSN--ILNRVTPGS--C-SRRKKYGCRR--KDTV
RRLQPI-------------------SHVTPSSETVTML-----PVSQS-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DDKSNSPKVVPSSSS-ESCSP-VVTL----TSS
LHHPV--KAALSEGGMNESTCISK-RCSNSEV--ISINPKNPKLSDGITGGG--YSLTL-
--------------------SPPGVFNNNN---PQQS-TPNDVHTSVSHVQ---------
-----NVLSFPTAFPKNSLHLKPITINPDR------------ENGLAKTEFSDLASQNKT
FDPKKGNLILLLSDFYYGQH----------------QGDG---QPEQKTHTTFKCPSCLK
VLK-NVKFMNHVKHHLELEKQRG-DSWETHTTCQHCHRQFPTPFQLQRHIESVHTPQ-EP
SAVCKICELSFKTDQILLEHMKDNHKPGEMPYVCQICSFRSS-AFADVETHFRTYHENTK
NLLCPFCLKIFKTATPYMC-----HYRRHWE-RGVHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKIVIQVSLEPGQPESVNV---ASIILS-TTDSEPSPPKS-KNRIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MELPCMIREE-EEEPELWKSEGETKQ----VDDDDAELILVG
VEHVNEDADVIFV---GMTSTSKL-VISN--ILNRVTPGS--C-SRRKRYGHFR--KGNT
HKLQPV-------------------NHVTPTSEAKTVL-----PASDS-ESRSTDIPI-I
IEP----LSQA-------------------------------------------------
---------------------------DYKNISPQIVPNSFS-ELCSS-LITF----TSS
CQHPL--ETAVSAGDMNKSPHVSK-RLYTCET--NSRNPKRPKLSDGIIGE---HSLGF-
--------------------SLSGFFHT---VTTQQST-PDRVHISLSHVQ---------
-----NGEPCPTPFPKDKVHFKPVRP--LG------------ENGLTKTDFPSFASPNKT
IDPTEGNLIVLLGDF-YGEH----------------IGVW---QPEPKTHTAFKCLSCLK
VLK-NVKFMNHMKDHLEL----G-NSWKNHTTCQHCLRQFPTPFQLQCHIESVHTPQ-EP
SAVCEVCELSFETDQVLLQHMKDNHKPGEMPFVCQVCSYRSS-FFADVDAHFRAFHGNTK
NLLCPFCLKIFKTAAPYRR-----HDRGHWE-KSFHQCSKCRLQFLTFKEKREHKTQCHQ
MFNKPKKLEGLSPTTKVVIQVSLEPLQPGLVEV---ASITVN-TSDFESSPPKS-KSMGF
N-----Q-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRIVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMNESSFLSK-RPSTSEV--NNANPKKPKPSE---SVSGANSSTVL
PSVKSPSVT------------------------SSQAMLAKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFCDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKAQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPA---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKFNTSKPNTI--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPTKEQ------EPVSKEIGRP------NMAERETETSNSESK
QDKAASSEEKNGCNANSFEGSSATKSEESL-RVSDKENETCLADQETGCKNIFSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMRQ-SSENIILSAQIKDHN-SSEARFSSKN-IKDLR
LTS----DNVSIDQFLRKRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTIEATVDLADEKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPYVLCSKE---P-------------SQAPDE-DELIFVG
VEHGREDPELIFV---GTSSNSKP-ANSN--ILNRVTPGS--R-LKRKR-NCLT--TTTP
PRQQPS-------------------GPAAPSSDTVIVL-----PESPT-ESRSTDSPI-I
IDP----LSEP-------------------------------------------------
---------------------------DCRSNSPQIVPESSS-EGSPL-GITS----SSK
-PRPV--RAALPAGDLNESPYV-------SKF--NVINPQRPEI-IEIEED---HSSAS-
--------------------SPAGTFHTLS---PQPSPCSRDVPRSLNHIM---------
-----NGAP------LPV---------HPCQ-----------EKGQAGVGFSSLAGLE-T
LDPRKGSLTLLLSDFYYGQH----------------RGDG---QPGQKTHTSFKCPECLK
AL-KNIKFMNHAKHHLELERQGN-DGWETHTTCQHCHRHFPSPFQLECHVDRVHTAP-DP
TTVCRICDLSFETDHVLLQHMKDNHKPGEMPYVCQICNYRSS-AFADVETHFRKCHVNTK
NLLCPFCLKIFKTATPYMS-----HYRGHWE-RSGHQCSKCRLQFLTFKEKMEHKTWCHQ
TFKKPQQLEGLPPDTKVVIQVSAEPVQSESGKV---ASITVS-TTDWEPSSSRS-QGRPS
K-----RPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEVPL-LCEE-EQDPQPQPSFQETRQ----TDDEDAELIF--
------DAELIFV---GVTSNSKP-AIST--ILNRVTPGS--R-LRRN-QGHRR--RNTA
HRLQPTSP-----------------------------------AASPS-ESRSTDSPV-V
IEP----LQES-------------------------------------------------
---------------------------DYKNNSPQVVPSSSS-KSCSP-EVIF----ISS
WRRPV--KAALSVGGVKESPHVSK-RHSASEV--DGGSPQRPKLNAEVAKG---ASSAL-
--------------------SPPGTCHAGN----QQSAPSGGGSVTSNRAQ---------
-----S--------------GPPTSVNPDR------------ENGLSKSDCSGLESQKET
SDPKKGNLILLLSDFYYGHH----------------RGNA---QAEQKTHSAFKCLLCLK
VLK-NIKFMNHVKHHLELEKQSG-DSWEKHATCQHCHRHFPTPFQLERHVDNVHTAQ-DS
AAVCKICELSFETDQVLLQHMKDNHKPGEMPYVCLVCNYRSS-VFADVDAHFRKCHINTK
NLLCPFCLKIFKTGTPYMC-----HYRGHWE-RSVHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSLEPGQSASVKV---ASITVS--CDSEPSSLRS-KGRIS
K-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPFTVDDEDEQDPEPQPRSGEPIQVLDDDAAEDAELIFVG
VEKVKEDAELIFV---GVTSASQP-ANSN--ILNRVTPGS--R-LKRKH-DRLR--ATTT
QRLQPS-------------------RPAAPTSEAVVVL-----PASPA-ESRSTDSPI-A
IEP----LSES-------------------------------------------------
---------------------------DYRSSSPQVVPSSSS-KCCSP-LVTL----SSS
ENSPV--KAALSGGDLNENLYVSK-CHF-------SINPQRPDHSIEIVEP---LSSAL-
--------------------PPSGTFHTSN---MQQRTPSFDAPNSLSRLV---------
-----NGAPPSE---DSA---------HPRQ-----------DSGLAEADFSSPASQE-T
FDPKKGSLTLLLSDFYYGQY----------------KGDG---KPEQKTHTTFKCPSCLK
AL-KNVKFMNHTKHHLELERQGSEDAWESHTTCLRCHRQFDSPFQLECHIDRVHTSP-DP
SVVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSS-GFADVETHFTKCHVNTK
NLLCPFCLKIFKTGMPYMC-----HYRGHWE-RSGHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSLQPVESESVKV---ASITVS-TTDWEPSNPRP-QGRLS
Q-----KPH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYGHLR--KDTA
NKLQPK-------------------SHETLTSEAVTVL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYRNSSPQVVPNNSS-ELPSPLI-TF----TGS
LHHPV--SAALSVGGINESPHVSK-RLSTFEV--NSINPKRAKLRDGIMEG---NSSAS-
--------------------SPSDTFHTMN---TQQSTPSNNIHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ENELAKTDILSLTSQSKT
FDPKKENPIVLLSDFYYGQH----------------KGDV---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQRN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSAHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------------MEQSCEE-EKEPEPQKNIQETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GVTSNSKP-VVSN--ILNRVTPGS--W-SRRKKYDHLR--KDTA
RKLQPK-------------------SHETVTSEAVTVL-----PASQL-ESRSTDSPI-I
IEP----LSKP-------------------------------------------------
---------------------------DYRNSSPQVVPNNSS-ELPSPLI-TF----TDS
LHHPV--STALSVGGINESPRVSK-QLSTFEV--NSINPKRAKLRDGIIEG---NSSAS-
--------------------FPSDTFHTMN---TQQSTPSNNVHTSLSHVQ---------
-----NGAPFPAAFPKDNIHFKPINTNLDR------------ANELAKTDILSLTSQNKT
FDPKKENPIVLLSDFYYGQH----------------KGEG---QPEQKTHTTFKCLSCVK
VLK-NVKFMNHVKHHLEFEKQRN-DSWENHTTCQHCHRQFPTPFQLQCHIENVHTAQ-EP
STVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCPFCLKIFKTATPYMC-----HYRGHWG-KSAHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVTIQVSLEPLQPGSVDV---ASITVS-TSDSEPSLPRS-KSKIS
K-----KSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MERQFMLCGEEQE-P-------------SRAHDEDAELIFVG
VEHVNEDAELIFV---GKTSNSKP-ANSN--ILNRVTPGS--R-LKRKR-NSLR--KTTT
ERLQPSSAAAPASETVIVLPASPAESPAAPTSETVIVL-----PASPA-ESRSTDSPI-I
IEP----LSEP-------------------------------------------------
---------------------------DYRSNSPQVVPGSSS-KGSPL-VPIS----SSK
HS-PV--KAALSVGGWNGSSS-------ASKL--NVINPQRPEFIIEIDEE---HSSAS-
--------------------SSSGTFHTSN---PQPSTPSSDVPKSVNRVV---------
-----NGAP--------------------LS-----------ENAIYIMGFSSPASQG-T
FDPKKGSLTLLLSDFYYGQH----------------KGDG---QPEQKTHTIFKCPNCLK
AL-KNVKFMNHTKHHLEFERQGN-DGWENHTTCQHCHRQFNSPIQLEFHVDRVHIAP-DP
TMVCKICELSFETNQVLLEHMKDNHKPGEMPYVCQICNYRSS-VFADVETHFRKCHVNTK
NLLCPFCLKIFKTGTPYMC-----HYRGHWE-RNGHQCSKCRLQFLTFKEKMEHKTRCHQ
MFKKPKQLEGLPPETKVVIQVSVDPVQSESGKV---ASVTVS-TTDWDPPSPRS-QGKPS
K-----RSH---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------NSKMAELFMECEEEEL-EPWQQKVEEIQK----KD----------
-D----DDELIFV---GEIASSKPAI-SN--ILNRCSPGS--S-SKGLKNDSFN--PDNS
---KPTSQ-----------------QYRNPSPNP-----VATLPEFHP-ESKSSESS--G
FQT----VSKP-------------------------------------------------
---------------------------SFSMTSSQDDPGTSS-VLQLD-STNDTPS----
-----SSILKKSTEGIDQTSLGLK-HPSTSKVS-S-VNPKKPKTNE---SVSETSP----
------SET------------------------FSQVVVS-NENTSSFHSK---------
-----TGAPSLTSCPKCNVKFSYLDPLKCHMKRCCPDMINNFLETL-KSEHSKAENKSNI
VLEK-GKLIMLVSDFYYGRH----------------EGAVE---EELKTHTTFKCFSCSK
VLKNNIRFMNHMKHHLEHEKQNI-ESWENHTTCQHCYRQYPNPFQLQCHIESTHTPH-DF
STICKICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSS-IFSDVETHFRSSHENTK
NLLCPFCLKISRMATPYMN-----HYMKHQN-KGIHRCQKCRLQFLTCKEKIDH-KLEHR
TFIKPKELEGLPTGTKVTIRASLGSAQSRSSSP---PSSSIPS-TSLQVSASES-TNTTT
K-----NNSKVLGNKSKISKPQIVLT------------------------TVSTPSTSKP
GPSATKSK--AKTSNKQK----------KQRTRKDKFSVALKNLRCH-------------
----QGTHT----CIECHSEIKDFPSHFSADLNCNFCKYTTNCNKAFTNH-MSSHSDHPS
KQFYIFKRHSRT-LRG-ITLVC-LKCDFLVDTSGLDRMAKHLNQRKTHTCQVIIEDVP--
ERTSTSESTSDGLLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------MVTTYIKSDLQLD-G-RQ
F---------FQPKDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGIKNGILNR--GFT
ASFKPTSQ-----------------RCLNSASNPVAALP----VNFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYVTNSPRVLSNNSS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGLNETSFLSK-RPSGSDI--SSVNPKKPKPSE---NTSGIDASSVI
SSEKSPSVI------------------------SLQVVPSQGANCSSSQSK---------
-----NGTTFPRACPKCDIHFNLLDPLKNHMTYCCPDMINNFLGLT-KADNLNSANEAKT
LESEKGKLIMLVNDFYYGKH----------------EGDVL---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSEVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVT---PSISP-STSTLQLSPPEP-DNVTA
K-----NHVKLTTSTPNTT--IS---------------------------DPSKANETKS
NGSKSKNK--SKVSNMQKKQSTL-----SSSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRYCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHSCRVLVEQVSVC
IPTSERL--SE--IKTEAPTKGQ------EPVSKETAR------HSRAEGEPGASHSGSK
QDKVPSSEEGTGCDASVCEAAAATH-CEKDVTVSDTEN-------VSSSKNILSHDPD--
-VGTDTMEKEEKTHHACQEME-LKVDQ-SSESTN----------PTEAELSSET-RQGLQ
LTS----GDVGIDQFLRQGDEPKSVNSDASDPGSVRLEPLTPSEVLEYEATEILHDGDD-
--PSANTSDTVSDQTGGSPGGSNPCRAETAVDLADGEERS---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------ASKVATLS-----PVSPS-EVRSTDSPI-I
IEP----SSNP-------------------------------------------------
---------------------------DYKNNSPQVKPNSAS-ELCSP-LIRF----TSS
LQHPG--GAAFSVGGVNEGRRVSK-QLSTSEV--NSTNPKRPKLSDGVPGG---HSLAL-
--------------------SSLGISPTRN---VQQNIPSKDIYTSLSRVQ---------
-----NRAPFPTAFPKDSANFKTLNLDR-E------------NGGRAKTDFSRIASENKT
FDSQEGNLIVLLPDFYYGHS----------------EGNG---QPEEKTFTNFKCLSCLK
VLK-NVRFMNHMKHHLELERQRS-NSWDSYTICQHCNRQFLTPFQLQRHIESVHVSQ-DP
STVCKICELSFETDHVLLQHMKDTHKPGEMPYVCQVCNYRSS-AFADVETHFRSRHENTK
NLLCPFCLKIFKTAVPYMC-----HYTGHRE-KSVHQCSKCRLQFLTFKEKMEHKTQCHQ
MFTKPKQLQGLPPETKVVIQVSPAPPHLGSAGV---ASITVS-SSELPPLGLK----ELP
G-----KPI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
---------------NSDMAELFMECEEEEL-EPWQKKIKEVED----D-----------
-----DDDEPIFV---GEIASSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALSR--GIS
AAFKSTSQ-----------------HYTNP-SNPVAASP----VNFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYLTKSSRVVSSNSS-ELLFD-LTQDTEL---P
---QYQGIPTISVAGMNENLFLSK-RPSASEV--NSVNPKKPKPGE---SVSVTDSSAVF
PVAKSPSLM------------------------SPQAMSSKGENTSSNQSK---------
-----DGTPFPRACPKCNIHFNLLDPMKNHMQYCCPDMINDFLGPD-KTENSNTANKAMT
ADSEKGKLIMLVNDFYYGKH----------------EGDIQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-DF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKIDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVAPLQSGPSTT---PSISA-STSTLQLSPPRT-ENTPA
K-----SPTKLSTSKPDTT--RS---------------------------E-----ASKP
NGSKSKCK--SKVSNIQKKQSTL-----VNSNKKSKVNTSLRNLRCS-------------
----RGVHK----CIECSSEIKDFANHFPTYVHCGFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVVLEKVSVC
IPTSEHL--SE--KLQGILWLKE------KQKHQVLKASKMKILHQKKKMNVIQIYPKVY
HQQKKKKM----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEDDD----DDD---------
DDDDDDDDDPIFV---GEIASSKPAI-SN--ILNRVNPGL--Y-SRGIKNG-------VT
TAFKPTSQ-----------------HYTNSTSNPVSASP----VNFHP-ESRP-------
------------------------------------------------------------
---------------------------------SNTVSNNSS-ELLFD-LTQDTGL---S
---PYQGGPALSIAGVNESSFISK-CPSASEG--NSVNPKKPKPSE---SVSGTDSSAVF
PSINSPSQT------------------------SSQAMPSKGANTSSNQSK---------
-----NGTPFLRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSNTVN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGD--------KTHTTFKCLSCLK
ILKNNIRFMNHMKHHLELE--------------------------------NIHIPH-EF
STICKICELSFETEHVILQHMKDNHKPGEMPYICQVCNYRSS-SFSDVDAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHMTQRHR
TFVKPKQLQGLPPGTKVTIRAS-------------------------VLSPPRT-KNITA
K-----NPTKLNTSKPNTP--KS---------------------------NASKSNGSKP
NGNKSKYK--SKTSNVQKKQSTL-----ANSNKKGKVNTALRNLRYR-------------
----RGVHK----CIQYCSEIKDFANHFPTYIHCSFCRYNTSCSKAYVNHMMSFHSNCPS
KRFVYLRFNTKL-TLTKFLFVSQLLNIFLNRFQR--------------------------
-------------------------------------MSRVHLM----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MEQPYMLCDE-DQEPEPQKNVKETKQ----VDDEDAELIFVG
VEHVNEDAELIFV---GMTSNSKP-VVSN--ILNRVTPGS--C-SRRKKYGRLR--KDTA
HKLQPT-------------------SHVMPASGAVTVL-----PASQP-ESRSTDSPI-I
IEP----LSKS-------------------------------------------------
---------------------------DCKNSSPQVVPNSSS-ELCPPLI-TC----TSS
LHHPV--REALSAEGMNESPCVSK-RLSTSEV--NGISPKRAKLRDGITEG---DSSAV-
--------------------SPSGIFHTVN---TQQSTPSDNVHTSLSHIQ---------
-----NGVPV-CAFPKDSVHCKPTNADLDR------------EKGLAQTDFSALATQNQT
LDPKKRNLIMLLSDFYYGQH----------------KGDG---TPEQKTHTTFKCLSCLK
VLK-NVKFMNHVKHHLELERQRS-DSWENHTTCQHCHRQFPTPFQLQCHIESVHTTQ-EP
AAVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQICNYRSS-AFADVEAHFRTCHENTK
TLLCPFCLKIFKTATPYMC-----HYRGHWE-KSIHQCSKCRLQFLTFKEKMEHKTQCHQ
MFKKPKQLEGLPPETKVVIQVSLEPLQSETVEI---ASITV-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNK
PFQP---------KNISKMAELFMECEEEEL-EPWQKKVEETQD----E-----------
-----DDDELIFV---GEISSSKPAI-SN--ILNRGHSSS--S-SKGIKSEPHS--PGIP
EIFRTASQ-----------------RYRDPPSNP-----VAALPRFHP-VSKPSQSSV-T
VEN----VS-K-------------------------------------------------
---------------------------PDFTKNSQVGSDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNTSYVLK-HPSTSKV--NSVTPKKPKTSE---NVPQINPSTSL
PLIGSPPVT------------------------SSQVMLSKGTNTSS-PYD---------
-----AGAHYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSEHPCAEDKNKT
DAET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPLQSKLPTA---PSGCTPGTSFLQVTPPTS-QNTTA
K-----NPRKSNAGRSKTRKPHAPTSTAS------------------------KAHTSKP
RGRIAKSK--AKPSYKQK----------RPRNRKNKMSLALKNLRCR-------------
----RGIHK--CI--ECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPG
KRFCIFKKHSGT-LRG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
ESTSTSEPISGCSLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNK
PFQ---------PKNNSKMAELFMECEEEEL-EPWQKKVEEIQD----E-----------
----ED-DELIFV---GEISSSKPAI-SN--ILNRGNASS--S-SKGIKNETLN--QGVT
DAFKPTSQ-----------------HYKDPTSNP-----VAALPRFHP-ESKSSHSSV-I
VQN----VSKP-------------------------------------------------
---------------------------DFTKNSSQVESDDSS-DLLFD-LTQDT-I---P
---LXXXXXXXXXXXPDETLPIIK-RPSASKV--NKINSKKPKTSE---DVSEINSCASL
SLVNSPLVT------------------------SSPVMISKGTDTSSIEHK---------
-----TGMPFQRSCPKCNVQFNLLDALKYHMKCCCPDMLNQFLEMV-KVEISSTENKDKA
GAEK-GKLIMLVSDFYYGRH----------------EGAVD---DEQKTYTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQNS-ESWESHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHTLLQHMKDTHKPGEMPYICQVCQFRSS-TFSDVETHFRASHENTK
NLLCPFCLKVSRMT-PYM------HYMKHQK-KGVHRCTKCRLQFLTCKEKLDH-KTQHR
TFIKPKELEGLPP---VTIRASFGPLHSKTSTAS---SNNTPSTSSLQVSPPRS-KNTTA
K-----SSTKSNASKTKTHKAHATTSTAS------------------------KPNASKQ
GKGTSKC--KAKTSYKQK----------KQRNRKNKISIALKNLRCH-------------
----RGLHK----CIECHSKIKDFASHFSIYIHCNFCKYNTNCNKAFVNHMVSSHSNHPS
KRFYIFKKHCGT-LRG-ITLVC-LKCDFLTDSSGLDRMAKHLSQRKTHTCQVIVENVP--
KSTSASEPTSDYLVK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MGDIFL-CKKVESP---KKNLRESKQ--REEDDEDPDLIYVG
VEHVHRDAEILFV---GMISNSKP-VVSN--ILNRVTPGS--N-SRRKK-GHFR--QYPA
HVSQPA-------------------NHVTS--MAKAIM-----PVSLS-EGRSTDSPV-T
MKS----SSEP-------------------------------------------------
---------------------------GYKMSSPQVVSPDSS-DSLPA-GT---------
-QRLV--GAMVSGGGRNESSPDSK-RLSTSDI--NSRDSKRVKLRDGIPGV---PSLAV-
--------------------VPSDISSTIS---TNTPSQG--VCNSSNHVQ---------
-----NGVTFPWADANGKAHFNLTNPERANE------------SGLAMTDISSLASQNKT
FDPKKENPIVLLSNFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NIKFMNHMKHHLEFEKQRN-DSWEDHTTCQHCHRQFPTPFQLQCHIDSVHIAM-EP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCLFCLKLFKTAIPYMN-----HCWRHSR-RRVLQCSKCRLQFLTLKEEIEHKTKDHQ
TFKKPEQLQGLPRETKVIIQTSVQP---GSSGM---ASVIV-------------------
--------------------SNT-----------------------------------DP
QSSPVKT-----------------------KKKTAMNTRDSRL-----------------
---------------PCSKDSS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------MADHFS-LNEEQKPELPKQHERESNQ--RHKHDEDDELIFVG
MEHVREDSDILFV---KMISNSKP-VISN--ILNRVTPGS--Y-SKRKR-GHLS--QDPT
PESHPG-------------------FHVTPTAKAMAAM-----PNSQS-EWGSRDSPI-T
TES----SYKL-------------------------------------------------
---------------------------AYKMSSPEVMPPR--------------------
---------------------DSK-QLSSADK--TSRNPKRSKLRNEIPSV---YSSTT-
--------------------TPSSVSPLMY---TGTPSKS--ICSP-STVQ---------
-----NGTSFPRTHANEKVPFVLGDPDPENS-----------SEALVKTGISHPTGQNKT
FDPKTGSLILLLSDFYYGHH----------------KGDG---QPAPKTHSTFKCLSCLK
VLK-NIKFMNHMKHHFELEKQRG-DSWENHTTCQHCYRQFPTPFQLQCHIDRVHTTQ-EP
AAVCKICELSFETDQVLLQHMKDSHKPGEMPYVCQLCNYRSS-AFGDVETHFRTCHENTK
DLLCLFCLKIFKTANSYMN-----HCWRHWSKKRVFPCSKCRLQFLSLKEEIEHKSKDHQ
TFKKPEPLEGLPPRTEVIIQTSVHS---S--GT---ESIMV-------------------
--------------------GNID-----------------------------------F
GLSPIKT-----------------------KK--RKNSRYSRV-----------------
---------------LCSQGSG--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDNK
TFQP--------K-NVPKMTELFMECEEEEL-EPWQKKVEKTED----E-----------
-----DDDELIFV---GEILRSKPAI-SN--ILNRGHSSS--S-SKRIKGEPGS--PGIP
EIFRTASQ-----------------RYRDPSSNA-----VAALPRFHP-ESESPQSSV-T
VEN----ES-K-------------------------------------------------
---------------------------PDFTKNSPDESDNAS-VLLFD-STQES-V---P
---PSQDIPAIFREGMKNSSYVLK-RPSTSKV--NTVTPKKPKTGE---DVSEINPSTSL
PLTDSPPVT------------------------SSHIRLAKGTNTSS-PYD---------
-----AEARYLTACPKCNVQFNLLDPLKYHMKHCCPNMITKFLGGVIKSERLCAEDKKEI
DPET-GKLFMLVNEFYYGRH----------------EGVAE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHMELEKQNS-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVCKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPHHSKLPTT---PSGYTPGTSFLQVTPPTS-QNSTA
E-----NPRKSNASKSKTSRPH------------------------ATTSTASKANTSKP
RGRIAKCR--AKPSYKQK----------RQRHRKNKMTLALKNLRCR-------------
----WGIHK----CIECHSKIKDFASHFCIHIHCSFCKYTTNCNKAFANHMMSSHSNHPS
RQFCIFKKHLGI-LSG-ITLVC-LKCDFLADCSGFDRMAKHLSQRKTHTCQVIIENVS--
QSTSTSEPTSDCPLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------PYMNPTSNPVTASP----VNFRP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYIMNSSRVVCNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGMNESSFLSK-RPSTSEV--NSVNPKKPKPSE---SVSGTNSLAVC
PSVKSPSVT------------------------SSQVVPPKGANSSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTANKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPV-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNFRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKELEGLPPGTKVTIRASVGPLQSGTSPT---PSNSA-SSSTLQLSPPRT-KNITT
K-----SPTKSDTSKPNT--TKS---------------------------SPSKPSASKP
NGNKPKYK--SKISNMQKKQSTL-----ANSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSED-LRG-ITLVC-LNCDFITDVSGLDNMAKHLSQHETHACQVVLEKVSVC
IPTSEHL--SE--LKNEALTKEQ------EPRCKEVTRP------NMAEGETETSNTESK
QDKTA-SGEKNECDANSFEGSLATKSEESLATVSDKENVTCLADPESGSKKIFNYDSN--
-IGVDKVEKEEQIQHVCQEME-LKMCQ-SSENITLCDQIKDYS-SSKAKFSSKN-IKDLR
LTS----GDVSIDQFLRRRDEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSEQTDHIPEENNPSTTETTVDPADEKERS---

------------------------------------------------------------
------------------------------------------MVTTYIKSDLQLD-G-RQ
F---------FQPKDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGIKNGILNR--GFT
ASFKPTSQ-----------------RCLNSASNPVAALP----GNLHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYVTNSPRVLSNNSS-ELLFD-LTQDTGL---S
---HYQGGPTLSIAGLNETSFLSK-RPSGSDI--SSVNPKKPKLSE---NISGTDASSVI
SSEKSPSVI------------------------SLQVVPSQGANYSSSQSK---------
-----NGTTFPRACPKCDIHFNLLDPLKNHMTYCCPDMINNFLGLT-KADNLNSANEAKT
LESEKGKLIMLVNDFYYGKH----------------EGDVL---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSS-LFSEVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVT---PSISP-STSTLQLSPPEP-DNVTA
K-----NHVKLTTSTPNTT--IS---------------------------DPSKANETKS
NGSKSKNK--SKVSNMQKKQSTL-----SSSNKKSKVNTALRNLRLR-------------
----RGVHE----CIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRYCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCRVLVEQVSVC
IPTSERL--SE--IKTEAPTKGQ------EPVSKETAR------HSRAEGEPGASHSGSK
QDKVPSSEEGTGCDASVCEAAAATN-CEKDVTVSDTEN-------VSSSKNILSHDPD--
-VGTDTMEKEEKTHHACQEME-LKVDQ-SSESTNPCDQSKEHN-PTEAEPSSET-HQDLQ
LTS----GDVGIDQFLRQGDEPKSVNSDASDPGSVRLEPLTPSEVLEYEATEILHDGDD-
--PSANTSDTVSDQTGGSPGGSNPCRAETAVDLADGKKRS---

------------------------------------------------------------
------------------------------------------------------------
------------------MGDIFL-CKKVESP---KKNLRESKQ--REEDDEDPDLIYVG
VEHVHRDAEVLFV---GMISNSKP-VVSN--ILNRVTPGS--N-SRRKK-GHFR--QYPA
HVSQPA-------------------NHVTS--MAKAIM-----PVSLS-EGRSTDSPV-T
MKS----SSEP-------------------------------------------------
---------------------------GYKMSSPQVVSPSSS-DSLPP-GT---------
-QCLV--GAMVSGGGRNESSPDSK-RLSTSDI--NSRDSKRVKLRDGIPGV---PSLAV-
--------------------VPSDMSSTIS---TNTPSQG--ICNSSNHVQ---------
-----NGVTFPWPDANGKAHFNLTDPERASE------------SALAMTDISSLASQNKT
FDPKKENPIVLLSDFYYGQH----------------KGDG---QPEQKTHTTFKCLSCVK
VLK-NIKFMNHMKHHLEFEKQRN-DSWEDHTTCQHCHRQFPTPFQLQCHIDSVHIAM-GP
SAVCKICELSFETDQVLLQHMKDHHKPGEMPYVCQVCHYRSS-VFADVETHFRTCHENTK
NLLCLFCLKLFKTAIPYMN-----HCWRHSR-RRVLQCSKCRLQFLTLKEEIEHKTKDHQ
TFKKPEQLQGLPSETKVIIQTSVQP---GSSGM---ASVIV-------------------
--------------------SNT-----------------------------------DP
QSSPVKT-----------------------KKKTAMNTRDSRL-----------------
---------------PCSKDSS--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
------------------------------------------------------TVNNYY
Q---------PLSINNSKMAELFMECEEEEL-EPWQKKVKEVDD----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGIKNGALCR--GIT
PAFKPTSQ-----------------HYTNPASNPVAASP----VNFHP-ESRSSDSSV-I
VQP----LSKP-------------------------------------------------
---------------------------GYVTNSSRVVSNNSS-ELLFD-LTQDSGL---P
---HYQGGPALSITGMNESSFLSK-RPSTSEV--NSVNPKKSKPSE---GVSGTNSSAVF
SSVKSLSVT------------------------SPQAMPSKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNVLGLA-KTEISSTANKNKT
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTYTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSTT---PSISA-STSTLQLSPPRT-KNITA
K-----SPTKSNTAKPNIT--KS---------------------------IASKPNASKP
NGNKPKYK--SKISNLQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGVHK----CIECYSEIKDFANHFPTYVHCSFCRYNTSCSKSYVNHMMSFHSNRPS
KRFCIFKKYSED-LRG-ITLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVVIEKVSVC
IPTSEHL--SE---------------------------S------NLAEGETETSNSESK
QDEASSEEIKNGCDVHLFEGSSTTKS-EEDVSVSDKENDNCLEDQETGSKNIFGYDSA--
-IDADKVEKEKQVENLCQETE-LKMCQ-SSENFIACDQIEDRN-AGGARFSSKN-IKDLR
LTS----GDVSIDQFLRKRDEHESVSSDVSEQGSIHLEPLTPSEVLEFEATEILQKGSGD
--PSAKTDAVVSDQTDNILGENSLSTTETTGDLVDEKERS---

------------------------------------------------------------
------------------------------------------------------------
------------------MAELFMECEEEEL-EPWQKKVKEVED----D-----------
---D-DDGEPIFV---GEIASSKPAN-SN--ILNRVNPGL--Y-SRGIKNGALSR--GVM
AAFKPTSQ-----------------YYTNSTSNPASASP----VNFHP-ESRLSNSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNPSQAVSNNSS-ELLFD-LTQDTGL---S
---PYQGGPALSIACVNESSFISK-RPSASEG--NSVNPKKPKPSE---SVSGTDSSAVF
PLINSPSQT------------------------SSQVMPSKGANTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPGMINNFLKLA-KTEFSNTAN--KS
VDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHRKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICEICELSFETEHVLLQHMKDNHKPGEMPYIFQVCNYRSS-SFSDVEAHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHHCTKCRLQFLTCKEKLDHKTQ---
--------------------PSVAPLQSGSSPT---PSISA-NTSTLQLSPPRT-KNITA
K-----NPTKLNTSKPNTP--KS---------------------------NASKSNGSKP
NGNKPKYK--SKTSNVQKKQSTL-----ANSNKKSKVNTALRNLRYG-------------
----QGVHK----CIECCSEIKDFANHFPTYIHCSFCRYNTSCSKVYVNHMMSFHNNRPS
KRFCIFKKHSED-LRG-ITLVC-LHCDFLADVSGLDNMAKHLRQHETHTCHIVTKKD---
AEAAQRF--QK--------------------------MSRVHLYSV-PLR----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
-------------------------------------------------------MDDDK
TFQP--------KIDIPKMTELFMECEEEEL-EPWQKKVEKTQD----E-----------
-----DDDELIFV---GEILSSKPAI-SN--ILNRGHSSS--S-SKRIKSEPVS--PGIP
EIFRTASQ-----------------RYRDPSSNA-----VAALPRFHP-ESESSQSSV-T
VEN----ES-K-------------------------------------------------
---------------------------PDFTKNSQVESDNSS-VLLFD-STQES-L---P
---PSQDIPAIFREGMKNASYVLK-RPSTSKV--NSVTPKKPKTSE---DVPEINPSTSL
PLTDSPPVT------------------------SSHVRLAKGTNTSS-PYD---------
-----AEAHYLRACPKCNVQFNLLDPLKYHMKHCCPNMITKFLGAIIKSERPYAEDKNEI
DPET-GKLIMLVNEFYYGRH----------------EGVTE---KEPKTYTTFKCFSCSK
VLKNNIRFMNHMKHHLELEKQNN-ESWENHTTCQHCYRQYPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSS-TFSDVEAHFRAAHENTK
NLLCPFCLKVSKMATPYMN-----HYMKHQK-KGVHRCPKCRLQFLTSKEKAEH-KAQHR
TFIKPKELEGLPPGTKVTIRASLGPHQSKLPTA---PSGYTPGTSFLQVTPPTS-QNSTA
E-----NPRKSNASKSKTSRPH------------------------ATTSTASKANTSKP
RGRTAKCK--AKPSYKQK----------RQRNRKNKMTLALKNLRCR-------------
----RGIHK----CIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPS
KQFCIFKKHSGT-LSG-ITLVC-LKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVS--
KSTSTSEPTSDCPLK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MGDN
P---------FQPKSNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSKPAI-SN--ILNRVNPSS--Y-SRGLKNGALSR--GIT
AAFKPTSQ-----------------HYTNPTSNPVPASP----INFHP-ESRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYITNSSRVVSNKSS-ELLFD-LTQDTGL---S
---HYQGGPTLSMAGMSESSFLSK-RPSTSEV--NNVNPKKPKPSE---SVSGANSSAVL
PSVKSPSVT------------------------SSQAMLAKGTNTSSNQSK---------
-----NGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLA-KTEFSSTVNKNTT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGASPT---PSISA-SASTLQLSPPRT-KNITA
K-----NPAKSNTSKPNTV--KS---------------------------NASKPNTSKP
NGSKSKYK--PKISNMQKKQSTL-----ASSNKKSKVNTALRNLRYR-------------
----RGIHK----CIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-ITLVC-LNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVC
IPTSEHL--SE--LKKEAPAKEQ------EPVSKEIARP------NMAERETETSNSESK
QDKAASSKEKNGCNANSFEGSSTTKSEESI-TVSDKENETCLADQETGSKNIVSCDSN--
-IGADKVEKKKQIQHVCQEME-LKMCQ-SSENIILSDQIKDHN-SSEARFSSKN-IKDLR
LAS----DNVSIDQFLRKRHEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGD
--PSAKTDEVVSDQTDDIPGGNNPSTTEATVDLEDEKERS---

------------------------------------------------------------
--------------------------------------------------------MGDN
L---------FQPKNNSKMAELFMECEEEEL-EPWQKKVKEVED----D-----------
-----DDDEPIFV---GEISSSRPAI-SN--ILNRVNPSS--Y-SRGLKNGTLSR--GIT
AAFKPTSH-----------------HYMNPTSNPVVTSP----VNFHP-ESRSSDSSV-I
IQP----FSKP-------------------------------------------------
---------------------------GYIMNSSRVVSNKSS-DLLFD-LTQDTGL---S
---HYQGGPTFSIAGMNESSFLSK-RPSTSEV--NNVNPKKPKPSE---SASGTNSSTVL
PSVKSHSMI------------------------SSQAMPLKGANTSSNQSK---------
-----NGAPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLP-KTEFSSTANKNMT
IDSEKGKLIMLVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
ILKNNIRFMNHMKHHLELEKQSS-ESWENHTTCQHCYRQFPTPFQLQCHIESTHTPH-EF
STICKICELSFETEHVLLQHMKDNHKPGEMPYICQVCNYRSS-SFSDVETHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGVHRCTKCRLQFLTCKEKMDHKTQHHR
TFIKPKQLEGLPPGTKVTIRASVGPLQSGSSPT---PSISA-SASTLQLSPPRT-KTIAA
K-----NSTKSNINKPNTT--KS---------------------------NASKPNASKP
NGSKSKYK--SKISNMQKKQSTL-----TSSNKKSKVNTALRNLRYR-------------
----RGVHR----CIECCSEIKDFTNHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPS
KRFCIFKKHSEN-LRG-INLVC-LNCDFLADVSGLDNMATHLSQHETHTCQIVVEKVSVC
ISTSEHH--SE--LKNETSTKKQ------EPVSKEIASP------NTIEG--GASNSESK
QDKVASSEEKNGGDANSFEVSSATKSKESIESVSDKENDTCLTDLETCSKKIFSCDSN--
-IGADKVEKEKQTQHVCQEME-LKICQ-SSENIISCDQIKDHS-SSETRLSSKN----LR
LIS----GDVSIAQFLRQRDEPESVSSDVSEQGSAHLEPLTPSEVLEYEATEILQKGSGD
QSPSAKMDEVVSDQTDDFPGGNNPSTTETAIDPAEEKERS---

------------------------------------------------------------
------------------------------------------MVTTYRKSD--------L
S---------FQPKDNLKMAELFMECEEEEL-EPWQKKVKEVEE----D-----------
-----DDDEPIFV---AEIASSKPAI-SN--ILNRVNPSS--H-SRGLKNGALNR--GFT
TSFKPTNQ-----------------RFPNPASNPVAALP----VNFHP-EPRSSDSSV-I
VQP----FSKP-------------------------------------------------
---------------------------GYLTNSPRVLSNNSS-ELLFD-LTQDTGL---S
---HYQGGPALSIAGLNESSFSSK-RLSGSDI--SSVNPKKPKASD---SIPGADASSVV
-PEKPPSVS------------------------SLQVVTSQGVNCSSNQSK---------
-----NGTTFPRACPKCNIHFNLLDPLKNHMTYCCPDMINNFWGLS-KIEISNTANEAKT
IDSEKGKLIMSVNDFYYGKH----------------EGDVQ---EEQKTHTTFKCFSCLK
VLKNNIRFMNHMKHHLELEKQSS-ESWEKHTTCQHCYRQFPTPFQLQCHIESTHTLL-DF
STICKICELSFETEQILLQHIKDNHKPGEMPYICQVCNYRSS-LFSDVESHFRTSHENTK
NLLCPFCLKVIKIATPYMH-----HYMKHQK-KGIHRCTKCRLQFLTCKEKMDHKTQHHR
TFVKPKQLEGLPPGTKVTIRASVGPLTSGSSTT---PFISA-STSTLQLSPPRT-ENVTS
K-----NPTKLNTSTPNTA--VS---------------------------DSSKPNESKP
NGSKSKNK--SKVCTTQKRQSTV-----ANSNRKSQVNTALRNL----------------
----------------------------------------------------SFHSNRPS
KRFCIFKKHSEN-LRG-ISLVC-LNCDFLTDVSGLDNMATHLSQHETHTCQVLIEKVSVC
IPASEHL--SE--LKTEAPTKGQ------ESVSKET-R------HNTAEGETGASHSEGK
QDKAPSSEEDVGCDASVCETPA-AANCEGNVTVSDTEN-------ESRSKNIFSHDSD--
-VGADNMGKEEQTQHTCQELE-LKVHQ-HSESTDSCDQSKEHD-SPADELSSET-GQDLQ
LTS----GDISIDEFLRQRDKPEPVSSDVREQDSVRLELLTPSELLEHEATEILHKGDDS
---SASASDAVSDLTGGLMS-PGGHGAETAVDLETGKKESEVM

Query Results

"ENSGT00530000063300_1"

ENSGT00530000063300_1