Query Results 

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTFLDILEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLL-AEHPFLEEMRSRG--ENLYVVMEVVEA----VQEVTLE---RAGR
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHIYNDNMYT------FPPGEKPEDEKFT--------------------
---------------------------------------------L---IQASDVG----
-A--VHEDFRT----LKEEVQRETWEVEKLSPEG-KNSLLSSLSKLL--GKKKELQD---
LELTLEGALGKGHEE---TLEALPKNV---------LQS--KGAMDAILYFLGAL-A---
-----------------------------ELSEAQQKLL-VKS------VEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPELF----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------HPDGHCNLDLLDSGNPSAS---AF
-------------------------------QVAGTTGTPEGTMPDLSALLRSMPSA

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FVG
VVRSVLRELD-HKGELIPVDSLRNSTSFRPYCLLGRRPS--SSWFWRPP-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPGLQCSG--
--------------------------------------PFQFCDAVDGL-MQGSVGLATP
GEG-----KISGGAA---------VSGSSSA----------SMNMC-TLHVDP-NTWEAM
H-RE------RRLRQPEHKILQQLRSRG--DNIYVVTEVLQT----QKEMEVT---RTHK
QEGSGQFVLPGAMCV------QG-EG---QG--HRSQKKTITI-PSGSI-LAFR-VAQ-L
VI--DSD-WDIIFFPEKKQRT------FQPPTTGHSPIRGTRSW--LQQSLGL-------
-----------------------SS---------------ILESIY---NHLR--FLTAS
TECTVTENFQG----LQAEVEASSRELVRLERDL-SQHLLKDLGRVL--LDQPALQA---
LEELLEEGLYC---GRAEPLDGPAGAVLECLVLPNRELV--QELAVPIFYLLGAL-T---
-----------------------------ALSEIQHTLL-AEA------LETRTLSGQLE
LVGS----LLEKS---V----PWEKHSSVSLPPGLL----G-SSWG-E--EAPAWVLL--
-----EECGLEL--RVD-APHVCW---DPKAQGPTC-ALYASLALLSRLIQQSR------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MASF

PF04598 // ENSGT00530000063218_Domain_1 (118, 397)

FEN
EAKKVVEQLG-KKGDLIPVQSLFNCTRFRPFCLVRKKTKK-FPWFFEPT-F---------
-LDTYFSLMDILEPS----------------------------S---P--VPEVTSS---
-------------------------------------KPFHFYKTENGE-LKGEMDMEVT
-SGLLG--KVARDA-----------TSCHDL----------ALKLT-ILTVDP-NIWEVL
--RE------RKLKKPMHSFIQEVQNRG--EKLYVVT-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEK
VVRSVVRELD-H-KELTPVDSLWSSASFQPYSLLSRRPL--HSRFWRPR-Y---------
-MCVNLSIRDILEPD----------------------------A---P--EPVLECGG--
--------------------------------------TFQFHDAMDGQ-LQGSVNLEAP
GQG-----RLSGGAT---------VSGSSSA----------SMDLC-TLRVAP-NTWEAM
H-HE------RRLRQPEPKTLQQLRSRG--HDVFVVTEVLQT----QKEVEVT---RTHK
QEGLGQFALLGALCL------QG-KG---EG--HLSRKKTVTI-PSGST-LAFR-VAQ-L
VI--GSD-WGELGLHRRGGE----------AWKNHRPSSSADGH--PRSCFSFASM----
--------------------------------------RGFSYSSC---QFQS-DGSMEH
WLATT-DDFQG----LQAEVKAWAVGLEGLSKGL-CGRLLGGLGQVL--RDEPALQA---
LEESLEQGLCGG--QM-EPRDGPVGAILESLVLPSGQLE--MELADSVFYLLQAL-A---
-----------------------------VLSEAQHVLL-AEV------LETGALSGTFW
LVEC----LVEQS---S----PWQEHRAVSLPPERL----G-DSWG-S--EAPAWALL--
-----EVCGLEP--QVG-TPQVCW---EPGARSRVC-ALYACLALLLRLSRLC-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRKKKD-SRSSIWGQSDY---------
-IPVEFSLNDILEPS----------------------------S---S--VPETVVRG--
--------------------------------------PFHFSDIVIQK-HKA--DVSVN
-VGVEV--SVSGET-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAIEL----INNTVLY---NSSG
VNILGRIS-FWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-REKA----ILISDDDE-----QRTFQDESKISER-VFYCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLSQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SPGHLDGPGGAILKKLQQESNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDIQHDLL-ACS------VEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 807)

AFKE
FTRSVVQEMD-SGGDMIPVRSISDADRFHCFWLVRKKRT-----FLGSR-Y---------
-YKTDLTLADILEGE----------------------------EGESL--SDELDSACQ-
------------------------------GQ-KS---KFQMEDHVDSK-RKLTVKW-KG
-IEIEG------SF-----------QVSHKW----------KTELL-KNQISQ-QYLNTL
Q--N------RKLKRGLPPSFQSIRATR--ADLYLVTETLET----TKKQLLT-------
--NPKKQY--KLQSQIFQGSIDY-EH------NEQN-LGKVTI-PPKSV-VGYR-VKQ-L
VF-PNTE-RM--------------------------------------------------
-------SVYFGDKT-----KSFPE---------------GEK-----------------
PL--HLEDPSN----IKERVEDMVSGLHDLTEVE-QKEVLSSLMQCL--SEDGHLED---
LQERVFETLVSG----ELQMEGSSGPLLSSLFNTAGILL--KAPAETILDLLDAL-I---
-----------------------------ELPEE-KQFV-VEA------LKKRILPQLKD
QVRQPGVEQIFNNQAS----NPHD--MSWDTE----------------------------
-------------------------------ASDLC-ALYVAVSILLQLSKEHTSVSS--
-----------------------------------------------

------------------------------------MISAHCNLHLPGSS---DSLASAS
--------------------QLL-LAGRLPGRADAPDAPPLG-----RRRSRSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRRVVQELD-HGGEFIPVTSLQSSTGFQPYCLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPDVQRGR--
--------------------------------------SFHFYDAMDGQ-IQGSVELAAP
GQA-----KIAGGAA---------VSDSSST----------SMNVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKVLQQLRSRG--DNVYVVTEVLQT----QKEVEVT---RTHK
REGSGRFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--DSD-LDVLLFPDKKQRT------FQPPPTGHKRSTSEGAW--PQLP----------
--------------------------SG----------LSMMRCLH---NFLT-DGVPAE
GAFTED--FQG----LRAEVETISKELELLDREL-CQLLLEGLEGVL--QDQLALRA---
LEEALEQGQSL---GPVEPLDGPAGAVLECLVFSSGMLV--PELAIPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LQSQTLLGPLE
LVGS----LLEQS---A----PWQERSTMSLPPRLL----G-SSWG-E--GAPAWVLL--
-----DECGLEL--GED-TLHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PHGDLTPLDSLIDFKSFRPFCVVLRKRK--STLFWGAR-Y---------
-LRTDYSLLGLLEPG----------------------------T------SPT-DPTD--
------------------------------------AGSFGFKNMLDAH-LEGEVDVPRT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-TALESL
H-KE------RKLA-ADHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MI-SGQDEWDIPHLYNDSMQT------FPAGEK-----PEEEK-----------------
----------------------F---------------------TL---IQASDVG----
-E--VHEDFKT----LKEEVQRETREVGRLSQVG-QGSLLSSLCNLL--GKKKELQD---
LEFELEGALDKGHEV---TLEALPKDV---------LLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-AKS------MEKKILPVQLK
LVES----TLEQNFLQ-----EKE--GVFPLRPELL----S-SLREEE--LTLTEALV--
-----GLSGLEV--QRS-SPQYMW---DPDTLPRLC-ALYAGLSLLQLLAGSP-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FDR
ASKDVVKKLQ-G-RDLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PKPFIHVQSTD-LEA--NLNVA
-----D--IARGGVG---------YVGYGGY----------NIEVQ-STSIPN-PKLEIL
Q--N------RKLLDKLPTFMKFCRMER--KNLYVVTEAYEV----SKDTMLT---GLSS
VNLLVKGFFKQLFKV------RG-KA---GR----SEKYSIPI-PKGSV-LAYK-KQQ-L
VI-ENNT-CVILPSAT-KK-----KMTFPGTPKYASA-S-EPTEI-YRT-----------
---------------------------------------ELQGLWI---NDIEPIGRIQE
-P--AHLDFKC----LQYEVSEQTRLLPELSKDV-QEVVLSSFLSMLYEGDRNVLHD---
LMKMLEL----S---QLGHMDGPGGKILDELRKDSSNPC--VDLKDLILYLLQAL-M---
-----------------------------VLSDSQLNLL-ARS------VEMRLLPHQVE
LVTS----ILQPNFKY-----PWN--IPFTVQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLQKANSSFKPSL
RPGYI------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-IRTDYTLLDLLQPG----------------------------T------SPS-DLSD--
------------------------------------SGSFSFKKMLDAR-LEGEVDVPKT
-------VKVKGTA-----------GLSHSS----------TLEVQ-SLSVSP-KALDDL
Q-KE------RKLV-PEHSFLKEIKQRG--ENLYVVMEVVET----VKEVTLE---NAGK
AL--GCFSLPFFAPLGL------------QG--SLDHKEAITI-PKGCV-LAFR-VRQ-L
IV-KGKDDWDIPHVFNENLKT------FPTEEKPEEK-----------------------
-------------------IFSF---------------------IQ---TSDIYTA----
-E--VPEDFGS----LKKEVQSEAQEVAKLSREG-QVSLLKSLRNLL--GKKQDLQD---
LELAFEEALNKGHPV---SLEASPKDI---------ELS--RDVVEGILYFLGAL-T---
-----------------------------ELSEAQHKLL-TKS------MDMKILPLQLK
LVES----VMEQNFPK-----TEE--GLFPLNPELL----S-SLGDEE--LTFTEALV--
-----GLSGLEM--QRS-GFKYNW---DPDTLPQLC-ALYASLSFLQLLNKES-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------VSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 874)

IFEE
ITRVVVQEVD-VGGDMIAVRRILDADRFHRCSLVRGKRN-----FWGHQ-Y---------
-HGPDLTLEDVLERR----------------------------EGEGP--FDVLGLGPK-
------------------------------GK-ELQRLSSQVLDMVVSK-GMLTVKLPKE
-LTIAG------TF-----------HGSHKQ----------RVKIL-ETRIPQ-QYLDSL
E--H------GKLRGRLPALLHAIWRMR--ADLYLVAETPET----ARKGPWQ-------
--GNGSV---HFVQE------IW-QG------NHAK-HLGINQ-SELFF-PSTT-VKQ-L
IF-PNMG-RMSKQG----------------------------------------------
---LVGAGYLFLGQQ-----KSFPE---------------GK------------------
SL--R-----N----MKEKEQDM-----GLSEKE-QKDVLSCLRVQL--PLSDRAGL---
-------VLTSP----VSWPYVFEVLISGSLFNAAVFLV--KAQTDSILGIPDAL-I---
-----------------------------ELSEE-QRLG-AEV------LGKGTLHWLKD
PVGS----VLEQNWSE----QPQG--VGRDPD----------------------------
-------------------------------ARLLC-VLHVAVSILLQLVKGDLPSSS--
-----------------------------------------------

------------------------------------------------------------
-------------------------------------------------------P

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNLLDAQ-VKGEVDMPKT
-------VKVTGTA-----------GLSQSS----------TLEVQ-THSVAP-KALETL
Q-KE------RKLA-AEHPFLKEMQNRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFARLAL------------HG--SIKHKEAITI-PKGCV-LAFR-VRQ-L
MI-EGKDEWDIPHLYNDNMQT------FPPGEEPEEKIIL--------------------
-------------------------------------------------IQASETG----
-E--VHEDFRT----LKEEVQRETQEVEKVSQAG-KRSLLSSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---SLEALPKDV---------LLS--KEAMGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-IKS------MEKNILPVQLK
LVEC----TMEQNFLQ-----DKE--GVFPLQPELL----S-SLGEEE--LTLTEALV--
-----GLSGLDV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLTEAA-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRK-KD-SRSSIWGQSDY---------
-VPVGFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIVIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSG
VNILGKIS-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LVSCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-S--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLNDIQHDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYDLL--
-----EECGLRM--ELD-SPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------MISAHCNLRLPGSSDSP-------
---------------------AS-ASRILPGRPDAPLGPPTGTMPHPFSLLRSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-RSGELIPMTSPKDSPGFQPYFLVVRKPS--SSWFWKPC-Y---------
-KPLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRGGVELSAP
GQA-----KIAGGAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLQQPEHKILQQLRSRG--DNVYVVTEVLQT----QKEVEVT---QTHK
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SV----------LSMMGCLH---NFSA-DGVPAE
GTFTED--FQG----LRAEVEAISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGSSL---GPVEPLDGPAGAVLECLVLESRMLV--PELAVPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTVSLPPGLL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MCS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TVEE
CVKKLLEKTG-K-GDLKPIKHLSTANKLQECNVIFKEQ-ETWSFFSKKID----------
-KPAGFSVMEILEDS----------------------------G---SSSAPETVSSK--
--------------------------------------PIPV-NFMGQK-NQL--GVDLD
-ASLET--SVSYEN-----------A-VRRS----------SLEFQ-YVAI-S-QNLEEL
R--N------RKPLEQEPSFLQQLRKKN--TNLYVVTGIMKL----TKCTSLH---TEGS
VKGGGKLSIPLISYL------KG-IFQ-GEG--LKVHKEKMDL-PEDTV-IAYQ-RKQ-L
VF-KEDD-ILFYSKDDEQ-------ATFQDETKETMS-----------------------
------------------------------------------QVAH---QDILPIGRLEE
P---RSQDFNR----LQEEICNERRALDSFPRKL-QDTLFHSILAML--RDGEDFQN---
LMDLLEE----N---CSGHLDGHGGTILTEIQKNYEDPW--YIPVHCILYLLEAI-M---
-----------------------------VLTDIQHDLL-AQS------MERRILAQQRE
LVKS----ILQPNFKY-----PWC--IPFTLKPELL----A-ALHDED--VDITYGLL--
-----EECGLTM--EPN-NPRSTW---DLEAKQPLC-SLYGALSLLQQLVDP--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
R--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFRT----LKEEVQRETQQVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLL-----DKE--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEG
LVRSVVRELD-HSRELIPVDSLRSSTSYQPYRLLSRKSP--SSWFWRPR-Y---------
-TCVNLSIKDILEPD----------------------------A---P--EPELERSG--
--------------------------------------PIHFYDAVDGQ-LQGTMELGAL
GQG-----KISGGAA---------VSGSSSA----------SMNVC-TLRVDP-NTWEIM
Q-QE------RRLRQPEHKILQQLRNRR--DNVYVVTEVLQT----QEEVKVT---QTRK
KEGSGQFALPGNMCL------QG-ES---QG--HLSRKNTVTV-PAGST-LAFR-VAQ-L
II--GSD-WDILFFPDEKQRT------FPRTPKGHKPPRGAGSS--LKQAFRL-------
-----------------------S--SV----------LESIHDRL---KFLS-DGPLEE
LVVTED--FQG----LQAEVQAGSEELEHMEKNL-RQQLLRALGRIL--KDSLALQA---
LESSLEQGLCYG--GQVEQLDGPAGAVLECLVLPSRMPV--PELAAPVFYLLGAL-T---
-----------------------------VLSEAQRELL-ADL------LETGTLLEQLK
LVEH----LLQQS---S----PWQEQKAISLPPGLL----G-SSWD-K--EAPGWTLL--
-----EECGLVL--QVG-APHVCW---EPQAQGPTC-ALYASLTLLSGLHQEPR------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSI

PF04598 // ENSGT00530000063218_Domain_2 (118, 165)

FEE
ITRIVVKEMD-AGGDMIAVRSLIDADRFHCFHLVEEKRT-----

ENSGT00530000063218_Linker_2_1 (165, 285)

VFGYG-----------
--DK-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILD

PF04598 // ENSGT00530000063218_Domain_1 (285, 795)

NVDSK-GKLI------
--------------------------GSHDQ----------KIEIS-ENWISQ-QYLDTL
E--N------RKLKRELPFSFRSINRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNEIFQ---SHL---SY------EHKG-QREVTI-LPNRV-LSYR-VKQ-T
GL-SNNL-FFPSFFGAC-------------------------------------------
------FDICLRDKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--GSEDSRN----MKEKLENMESVLQELTEDK-RKDVLNFLTKCL--GREELWQD---
LEQKISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--GARAEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHD--MDCDPE----------------------------
-------------------------------ARIPC-ALYVVVSVLLELAEGTTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------SHRVSP---S--CYSRAVPLLRTNMPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 490)

MFKT
MAKSLVKEVG-K-KDLNPVSNLSSSHRFRPFCLLRKKSKK-HK-FWSKK-F---------
-TCTEFSLMDILEPN----------------------------S---P--VPEVNQE---
-------------------------------------RQFHFCKKVDGK-LMGAMGLDME
-KKIDMNIGVSAGI-----------EKSHGS----------FLEMQ-ILTISY-QTWTTL
Q-ME------RKLVKPEPTFIGELRSRG--EDLYVVIEAMEL----VNSPVLG---SKIT
LRGAGSISF-----PELV-NVEG-QG---HG--SRGKQKLMTI-PPHSI-LAYR-AAK-L
SI-SENS-WDSEDESKTG-------EEFLSV-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEK
VVKNVIKEVSGSRGDLIPVDSLRNSTSFRPYCLLNRKFS--SSRFWKPR-Y---------
-SCVNLSIKDILEPS----------------------------A---P--EPEPECFG--
--------------------------------------SFKVSDVVDGN-IQGRVMLSGM
GEG-----KISGGAA---------VSDSSSA----------SMNVC-ILRVTQ-KTWETM
Q-NE------RHLQQPENKILQQLRSRG--DDLFVVTEVLQT----KEEVQIT---EVHS
QEGSGQFTLPGALCL------KG-EG---KG--HQSRKKMVTI-PAGSI-LAFR-VAQ-L
LI--GSK-WDILLVSDEKQRT------FE-PSSGDRKAVGQRHH--GLNVLA--------
--------------------------AL----------CSI-GKQL---SLLS-DGIEEE
ELIE--ADFQG----LYAEVKACSSELESLEMEL-RQQLLVNIGRIL--QDQPSMEA---
LEASLEQGLCSG--GQVEPLDGPAGRILECLVLDSGELV--PELAGPILYLLGAL-A---
-----------------------------VLSETQQQLL-AKA------LETTVLSKQLE
LVKH----VLEQS---T----PWQEQSSVSLPTVLL----G-DCWD-E--KNPSWVLL--
-----EECGLGL--QVE-SPQVHW---EPTSLIPTS-ALYASLFLLSSLGQKPC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------AGSFGFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALETL
Q-GE------RKLV-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKPGEEKF---------------------
--------------------------------------------IF---IQASDVG----
-D--VHEGFKT----LKEEVQRETQEVDKLSRMG-QSSLLSSLSKLL--GKKKELQD---
LELELEGALDKGHEV---ALEALPKDV---------LLS--KEAMGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--SVFPLQPELL----S-PLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYASLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MLST

PF04598 // ENSGT00530000063218_Domain_1 (118, 833)

FEL
ITRSVVQELD-RKGNLIPLESLIDADKFHCCFLVYKRES--FFPFFKPR-Y---------
-CKTGLTMDDLLESQ----------------------------D---E--LDYISTE---
---------------------------------VKKRKKYGVEENAEKK-MNISLKLPQS
-I------SLEVNV-----------DCNKGY----------DLQLQ-HFEISE-KGKESL
Q--L------RKLKEEQPSLVQALKEKG--KNLYIVVETVEM----TEEQKVH---RKYF
LETLFQ-----VVLE---------KI-----KLYNNNSCAVTI-PSKSV-LAFR-TNL-L
VF-EKEC-CRIFYS----------------------------------------------
------------DDK-----NSFSL---------------ESGSGS-----RSGQTEEL-
SQ--PLQNFND----LQMKLMDLNGELQDLEKDQ-RKNVLDSLVKHL--KEGT-LKE---
LEE------RVMKVLLTEELDDSKDPVLSILFSSGGSFM--APKGDAILGFLQAL-I---
-----------------------------ELKEERQMLL-AVA------VEEKLLSETMT
LVKN----ILNQTSER-------------E-----P----K-PFSLKA--DSIPHILV--
-----IMCDPEY--QEDKELKVTW---NSEACHLFC-ALYIALSVLLLLA----------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFES
VVRSVVQELD-PRRELIPVDSLQNSTSFRPYSLLRRKPP--SSWFWKPR-Y---------
-SCVDLSIKDILDPD----------------------------A---P--EPDLEHGN--
--------------------------------------TFHFYDNTDGK-VQGNMEVAVP
GQG-----KIAGGAA---------VSGSSST----------SVNVC-TLSVGS-NTWVHM
L-QE------RRLRQPEHKILQQLRSCR--DDVYVVTKVLQT----QEEVEVT---HTRK
REGSGQCAVPGAMCL------KG-DG---EG--HLSRENKVTI-PAGSI-LAFQ-VAQ-L
VI--DSN-WDIFFFADEKRRT------FPPPPTEGQSQHP----------FSL-------
-----------------------S--SL----------LGLIHERF---KLWT-DGASEE
LVVTED--FQG----LRTEVEAGSAELQKLEREL-RLQLLLNLGEIL--CDPSALQD---
LETLLAQGLCGA--TQVKSLCGPAGDILGCLVQSSGVLV--QALAAPVFYLLGAL-T---
-----------------------------ALSETQQQLL-AKV------LDRGDLSTQLE
LVHH----LLEQS---T----PWQEQRDVSLPPKLL----E-SNWG-E--EAPGWTLL--
-----EECGLRL--QVD-APQVHW---EPEAQGPTC-ALYASLALLSGLSRESC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRRVVQELD-HSGELIPMTSLQNSTGFQPYFLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRGGVELSAP
GQA-----KIAGRAS---------VSDSSST----------SMHVY-SLSVDP-NAWQTL
L-HE------RHLRQPEHKILQELRSRG--DNVYVVTEVLQT----QEEVEVT---RTHR
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SG----------LSMMGCLP---NFLP-DGVPAE
GTFTED--FQG----LRAEVEAISKELELLDREL-CQLLLKGLEGVL--RDQLALRA---
LEEALEQGPSL---GPVEPLDGPAGAVLGCLVLESRMLV--PELAVPIVYLLGAL-T---
-----------------------------MLSETQRELL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQKRSTMSLPPGLL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPYVCW---EPQAQGCMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFRCFHLVGEKRT-----FFGCR-H---------
-YTTGLTLMDILDT-----------------------------DGDKW--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDST-GELIVRLPKE
-ITI------SGSF-----------QGFHHQ----------KIKIS-ENRISQ-QYLATL
E--N------RKLKRELPFSFRSINTRE--N-LYLVTETLET----VKEETLK-------
--SDRQYKFWSQISQ---GHL---SY------KHKG-QREVTI-PPNRV-LSYR-VKQ-L
VF-PNKE-T---------------------------------------------------
------MNIHFRGKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--G

PF04598 // ENSGT00530000063218_Domain_1 (606, 795)

SEDSRN----MKEKLEDMESVLKDLTEEK-RKDVLNSLAKCL--GKEDIRQD---
LEQRVSEVLISG----ELHMEDPDKPLLSSLFNAAGVLV--EARAKAILDFLDAL-L---
-----------------------------ELSE-EQQFV-AEA------LEKGTLPLLKD
QVKS----VMEQNWDEL-ASSPPD--MDYDPE----------------------------
-------------------------------ARILC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

SFQS
VTRRVVRELD-CPGNLIPTDSLLSSSCFQPYSMVGRKPS--TSIFWKAR-Y---------
-ASVNLSIWDILEPG----------------------------T---P--EPALQHSG--
--------------------------------------PFRVRDTVDGQQVQISLKLGTL
GQG-----SLTGGAT---------MSMNSRA----------SLNVC-TLCVDP-RTWDTL
P-EK------RRLRQPEHKVLQQLRSRG--DNVYVVTEVLQT----QEEVEVT---SSHT
KQGLGQLTLPGVTCL------LG-S-----------QEQTLTI-PSGST-LAFQ-GAL-L
VV--DPE-WNVLLFPDKKKRT------FQKPVPASNLTS-RRAW--PPLFT---------
--------------------------------------ELSLQKDC---RFQS-DGPMEE
LAVVK-KDFAG----LKAEVAAKGQVLGRLNCDL-RQELLGALQQLL--LDVPALQA---
LEEVLEQGLRS---GQAEPQEGPAGTVLECLVQPSRELV--KDVATAVFYLLGAL-T---
-----------------------------ALSDTHQLLI-AWA------LETGALQAQLQ
LVES----ILKQX---X----XXXXXXXXXXXXXXX----G-SGWG-K--DTPTWL-L--
-----EECDVQL--Q---DTHMHW---DPAAQGHAC-ALYAAMVLLLGLGPQPL------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VQEVTLE---RASK
AE--ACFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFRT----LKEEVQRETQQVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAMGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLL-----DKE--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFAG
VVKNVIKEVGGSGGELIPVDCLRNSTSFKPYCLLSRKLS--SSWFWKPR-Y---------
-TCVNLSIKDILEPS----------------------------A---P--EPEPECFG--
--------------------------------------NFQVSDVVDGN-IQGSVTLSGT
GQG-----KISGGAA---------VSGSSSA----------SMNVC-MLRVTQ-QTWEIM
Q-RE------RHLQQPENKILQQLRNRG--DDVFVVTEVLQT----KEEVQIT---QVHS
HEGSGQFTLPGASCL------QG-EG---KG--HQSRKKMVTI-PAGSI-LAFR-VAQ-L
LI--GSE-WDILLISNEKKRT------FELPSSGHKGAVGQRRH--DFSLLA--------
--------------------------VL----------HSI-GERL---SLKS-DGTNEE
EVIR--EDFQG----LRAEVEAGSSELRSLEMEL-RQQLLVDIGRIL--QDQPSMEA---
LEASLEQGLCSG--EQVEPLEGPAGSILECLVLDSGELV--PELAAPVFYLLGAL-A---
-----------------------------GLSETQQQLLATKA------LEATVLSKELE
LVKH----VLEQS---T----PWQEQRSVPLPSRLL----G-DSWD-E--EALTWVLL--
-----EECGLTL--QVE-PPQVYW---EPTSQGPIC-ALYASLALLSSLGQKSC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------AGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RRLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFTPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHKGFRT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 784)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------AGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
--QE------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAIAI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--------------------
-------------------------------------------------------R----
-D--VHEGFGT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVRE----KEQM--L-----------GRWP------------------------------
--------------GEI-GPQYIV---DKTQTPSPLRPLLRSL-----------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEE
VVKSVIKEVD-RKGELIPVDSLRNSTSFRPYRLLSRKLS--SSWFWKPR-Y---------
-RCVNLSIKDILEPS----------------------------A---P--EPEPECCG--
--------------------------------------RFCVSDAVDGN-IQGRVALAGT
GQG-----KISGAAA---------MSGSCSA----------SINMR-ILRVAQ-NAWDVM
Q-RE------RHLQTPEHKILQQLRSRG--DDVFVVTEVLQT----EEDVQVT---QTLS
KEGLGQLALPGALCL------QG-EG---KG--YLSQKKMVTI-PAGSV-LAFR-VAQ-L
LI--DPK-WDILLFPNEKKRT------FQQPPSSHRRQDGQRQH--TFNLLS--------
--------------------------TL----------WSM-GERL---KLLT-DGSHEE
QVTT--EDFQG----LRAEVKAVSTELEYLEMEL-RQQLLVAIGRIL--HDQPSMEA---
LEASLEQGLCHG--GQVEPLDGPAGSILECLVLPSGEPV--LELAVPILYLLGAL-T---
-----------------------------VLNETQQRLL-ARA------LEAAALSEQLE
LVEY----ILEQS---M----PWQEQSFVSLTPRLC----G-SSWR-E--GAPAWVLL--
-----EECGLAL--QVD-TPQVHW---GPKSQGPTC-ALYASLALLSGLSQKPC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
-------------------------------------

PF04598 // ENSGT00530000063218_Domain_1 (158, 890)

KE--KSTLIGAR-Y---------
-LRTDYTLLDVLEPG----------------------------S------SPT-DPTD--
------------------------------------TGNFGFKNMLDAQ-VKGEVDMPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALETL
Q-------------------------------------------------ELE---RAGK
AD--GCFSLPFFAPLGL------------QG--SINHKEAITI-PKGCI-LAFR-VKQ-L
IV-KGKDEWDIPHIYNDNMQT------FPPGXXXXXXXXX--------------------
---------------------------------------------X---XXXLPTG----
-E--LLEDFRT----LKEEVQRETQEVQKLSRVG-QHSLLSSLSKLL--GKKKELQD---
LELMLEGALDKGHEV---SLEALPKDV---------LLS--KDATGAVLYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPMQLK
L-----------------------------------------------------------
---------------------YLW---DPDTLPRLC-ALYAGLSLLQLLTEAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
TTKKLVKEIG-D-QELRPVKTLLSATKIHRFSLIQRKK--ARSWFWQRPD----------
-VPLDASLMDILEPG----------------------------S---S--VPDAAV-V--
--------------------------------------SVLFSDTEVLK-QQA--AGSMN
-AGAEV--GFSGET-----------AACQES----------SLDIQ-IVSTPH-ETWTEL
Q--K------RKLLDPEPALLKQCREAG--VNLYVVTDTVEL----CNSPVLP---DLSS
ANVSGKFFFPLNIFV------KG-EGQ-GGG--LKVREKKLIV-PKGSV-LAYT-RKQ-L
VF-YGRE-WEILHIGYSND-----QETFPAGKFQKKP-FQ----Q-PEIL--HIGYSNDQ
---------------ETFPAERIQE-------------PISLKFTK---RDLNHSGR-IQ
EP--ISLDFRL----LQEEVSQNIKA-AELSKDM-QGVVFSNLLAML--KDREDLQDCKP
LQDLMDK----E---PFGHLDGPGGTILTELQKDSCHPE--VGSKCLILYLLEAL-M---
-----------------------------VLSDIQHVLL-AQS------MEKRILLLQRD
LVGS----ILEPNFNC-----SEN--TPFTLQPELL----A-PLQGEG--LAITYGLL--
-----DECGLEM--ELN-SPRSTW---DPEAKEPLS-ALYGALSVLSQLAEV--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFEH
TSKNLVKELG-D-KDFRPLQNLLSAHKFCQLKLLRKKR-RTLSQFWEQPD----------
-VPVDHTLTDILEPS----------------------------P---S--VPEPVLSK--
--------------------------------------KFIFIDKTVWK-GAA--EVDVT
-AGLEV--SVSGTA-----------TQSCEC----------SLEVQ-SVTISP-WDWEDL
Q--K------RKVLDQEPSFLQECRTRG--DNLYVVTEAVKL----VNETVLQ---DSSS
VNATGTFSIPWSFYA------KS-TAE-GSG--LKERKRTMTV-PQGTV-MAYK-KKQ-L
VF-REDG-RAILLISDDDK-----QKTFPEIKLQGLP-LS-------PEI------LSIS
D--D-NKRKAFFVGKVQRQSA-------MG-----T------KRRP---IL--PIGRIQ-
EP--ISRDFKS----LQNEVSREIEAVAELPRDI-RDALFHTILAKL--KDQGALQD---
LTDMLDG-----------NLWDHTGSFLSEMREDSRNVW--LESRPCVIYLLEAL-L---
-----------------------------VLSDIQHELL-AWS------MEKRILPQQRE
LVES----ILEPNFRY-----PWN--IPFTLDPKLL----A-SLQDEG--LAVTFGLL--
-----QECGLRV--APD-NPKGTW---DLEAKKPLS-ALYGSLSVLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRSVVRELD-NTGQFTPVDSLGSSSSFRPYSLLHRKPS--RSWFWKPR-Y---------
-TCVNMSIKDILEPE----------------------------A---P--EPDLECVG--
--------------------------------------PFLFCDATDGQ-LEGSVQLAGP
GRG-----SIAAEAA---------VSKSHNT----------SMNVC-RLLVDS-KTLESL
H-RD------RRLRRPEPKILQQLRQRG--DNVFVVTEVLQT----QQEVQVT---QAGR
LEGSGQLGVPGAMSF------EG-KG---QG--HLSRKRTVTI-PEGSI-LAFR-VAQ-L
II--DSD-WDLLFIPEKKQRT------FQGPGRGDKPVPQMSSQ--S-------------
--------------------------CV----------ARCSLKHF---EFEE-DGSDKE
SGSTED--FQG----LKAEVEDISRQLLCMDATL-SQKLLGGLAAAL--RDPAALGA---
LEELLEQGLRG---KQLQPLDGVTSAVLECLMLSSGELV--EEIADPVLYLLGAL-T---
-----------------------------VLSGNQQELLAEVA------LDTEALAYHLQ
LVHN----LLEQS---S----PWQEPSIITLPTGLL----E-RGWD-E--NQPAWTLL--
-----EECGHEL--QAA-APQVHW---EPQAQDRTC-ALYTCLAFLCGLSRQLR------
-----------------------------------------------

------------------------------------MISAHCNLRLPGSSDSP-------
---------------------AS-ASRILPGRPDAPLGPPTGTMPHPFSLLRSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-RSGELIPMTSPKDSPGFQPYFLVVRKPS--SSWFWKPC-Y---------
-KPLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRGGVELSAP
GQA-----KIAGGAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLQQPEHKILQQLRSRG--DNVYVVTEVLQT----QKEVEVT---QTHK
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PLGSI-LAFQ-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SV----------LSMMGCLH---NFSA-DGVPAE
GTFTED--FQG----LRAEVEAISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGPSL---GPVESLDGPAGAVLECLVLESRMLV--PELAVPVVYLLGAL-T---
-----------------------------MLSETQHELL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTVSLPPGLL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

VFEN
VTRALARQLN-PRGDLIPLDSLIDFKRFHPFCLVLRKRK--GTLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------S------SPA-EPTD--
------------------------------------SGNFGFKNMLGAR-VEGKVDMPKT
-------VKVTGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALESL
Q-EE------RKLA-EDHPFLKEMRDRG--ENLYVVMEVVET----MQEVTLE---RAGK
AE--GCFSLPFLPRWGY------------RG--SVNHKEAVTI-PKGCI-LAFR-VRQ-L
MV-RGKDEWDIPHICNDNMQT------FPPGGKPEEKFVH--------------------
-------------------------------------------------IQASDVG----
-E--AHEDFKA----LKEEVQRETQEVKKLSQVG-QSSLLSSLSKLL--GNKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------QLS--KEAMGAVLYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-APQYTW---DPDTLPHLC-ALYAGLSLLQLLTKGS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
TTKKLVKEIG-D-GELRPVKCLERATKIRRFSLIRRKK--ARSLFWQLPD----------
-EPLDVSLMHILEPG----------------------------S---S--VPDAAVEV--
--------------------------------------SAVFSDTVVTK-QQA--AGSVN
-VGAEV--GFSGET-----------ASCRGS----------SLEYQ-IVSTPH-ETWDKL
Q--K------RKLPDPEPYFLKQCREAE--VNLYVVTDTVEL----LNSPVLQ---DLSS
KKILGKFSLPLDILV------KG-KGQ-AEG--LKVREKKLTV-PKGSV-VAYK-RKQ-L
IF-YRRG-WVIHHIADEDK-----QETFPADYTFVAS-SC--SSR-PPSFLPSFLLPSSF
F-IL-SKA-ATLGPELFFIIVFSLQ-------------HLVKGEQV---TLVPEAGSLQH
PL--LGADFKL----LQEEVSQNVKA-AELSKDM-QNVVFSNLLAML--GDREALQD---
LMDTLEQ----E---PFGHLDGPGGTILTELRKDSHYPE--VGSKCLILYLLEAL-M---
-----------------------------VLSDIQHVLL-AQS------MEKRILLPQRD
LVRS----ILEPNFNC-----SEN--TPFTLQPELL----A-PLQGEG--LAITYGLL--
-----DECGLKM--EVN-TTRSTW---DPEAKEPLT-ALYGALFVLSQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MLER
ISKNLVKEIG-S-KDLTPVKYLLTATKLRQFVILRKKKD-SRSSFWEQSDY---------
-VPVEFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DVGVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---DSSS
VNILGKIS-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-LAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYEISQM-VGYCAAR-SEEWLPSFPTISPT
LFNA-SSN-DM---KLKPELFLTQQ---FL-----SGH--LPKYEQ---VRILPVGRIEE
-R--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--RDRGALQD---
LMNMLEL----D---SSGHLDGPGGAILKKLQQDSNHAW--FNAKDPILYLLEAI-M---
-----------------------------VLSDFQHDLL-ARS------VEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DVEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
TSKNITKEIG-D-KDLRPAKNLLSATRIHQFSLLLKRK--THSQFWEQPE----------
-VPIEVSLMDILEPS----------------------------S---S--VPETVKTG--
--------------------------------------QFHITDTAVKK-WKA--RVSVN
-AGVEA--GLLPEA-----------AEFYGS----------SLQYQ-IVTIPF-HTWTDL
Q--K------RKLLDPEPLFLKQCRKTA--VNLYVVTEIVEL----LNSPVLY---ETRS
ENILGKFSFTWNMFV------KG-EGA-GER--LKVREKELTL-QKGMV-MAYK-RKQ-L
VF-KENG-WDILLISDDDK-----RNTFPEGEETLPW-PD-SSTA-SQSLLPLTLARAPG
HKES-HLS-PL---RTGTGVFSTSA---FF-----PGK--IMKQEE---VKQEGGGGIET
-P--FGQEFKH----LQEEVSQQMEALAQLSTDV-QDAIFHNILAML--GDRGALQD---
LMDMLEQ----E---HLGHLNGPGGTILNELRKDSRYQW--VKPKYPILYLLEAI-M---
-----------------------------VLSDIPHDLL-AQS------KEKRILFHQRE
LVRS----ILEPNFSY-----SWN--IPFIIKRNLL----A-PLQGEG--LAITYGLL--
-----EECGLKM--QLD-SPRSTW---DLEAKKPLS-ALYGILSMLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 485)

AFEK
FTKRVVRELA-SGEDMVAVRSLIDSGGYSCLSLVREKQS-----WFRLQ-Y---------
-FSTDLTLDDILEPK----------------------------EGQTP--ADEVDAASP-
------------------------------GQME----ELQFSDDVDSK-GEFTGKITET
-ATIRV---MTEKS-----------HGTQGQ----------KIKLL-VKQESE-KRLNDH
V--N------RKLKKEPPSKFKTFRAKR--INLYVVTKTVET----ANEALLR-------
--CHQQCGVFCKIFL---FGF-----------ECKN-EMSLTI-PSGRI-LGYQ-KKQ-I
VF-SNSG-KM--------------------------------------------------
---SNGLDICFLDRT-----ETFPK---------------XXXXXXXXXXXXXXXX--X-
XX--XXXX----------XXXXX-----XXXX-X--X--XXXXXXXX--XXXXXXXX---
XXXXXXXXXXXX----XXXXXXXXXXXXXXXXXAAGVLE--EGRVEAIPIFLDAL-M---
-----------------------------ELCEEDQKHV-FEA------LEKNMLPELVD
KVES----ALKEDWGEQ-YRNPHD--MDPDSE----------------------------
-------------------------------ARLVF-ALYVVLSVLLQLSEKPTSS----
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFHCFHLVEEKRT-----FFGCW-H---------
-YTT-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDSK-GKLIVELPKK
-ITI------SGSF-----------QGSHDQ----------KIEIS-ENQISQ-QYLDTL
E--N------RKLKRELPFSFRSINRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNQIFQ---SHL---SY------EHKG-QREVTI-LPNRV-LSYR-VKQ-L
VF-PNS------EITLP-------------------------------------------
----------------------LSA---------------EKDGA------SSCLG--K-
---------------VDWQ

PF04598 // ENSGT00530000063218_Domain_1 (620, 794)

LENMESVLQELTEDK-RKDVLNFLSKCL--GREELRQD---
LEQRVSEVLIFR----ELQMEDPVNPLLSSLFNAAGILV--EARAEAILDFLDAL-L---
-----------------------------ELSE-EQQLV-ADA------LEKGTLPLLKD
QVKP----IMEQNWGEL-VSSPHD--MDYDPE----------------------------
-------------------------------ARIPC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSSL

PF04598 // ENSGT00530000063218_Domain_1 (118, 371)

FLR
TTKSLVRELG-RKGELVPVDSLSRSPRLRPFCLVRKKHRR-YLWPWDTP-L---------
-IPTDFSLLDLLEPG----------------------------C---P--EPEVNHS---
-------------------------------------SPINVWEKVAGG-LTGAVSLS--
-TGLQG--QVTGGS-----------NSAYIS----------ALAVQ-TLWVSP-CTWEML
L-EK------R-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSKFEE
ITGVVVQEMN-SRGDMIAVRSLIDADRFHCFCLVREKRN-----FLGCR-Y---------
-YTTDLTLEDILERE----------------------------EGEGP--FDKPDSGLQ-
------------------------------GQ-KA---EFRAVDMVDSK-GELSVKLPKE
-MTI------SGSF-----------QGSQEQ----------EIKIL-HTRIPQ-KYLDSL
E--N------RKLKRKLPTMFKSIQKRR--ENLYLVTETVET----TEENTLE-------
--SEQRYTFWSQLHL---GSL---KF------KRKQ-KRAVTI-PPKRV-LGYR-IKQ-L
VF-PNME-RMEKDGG---------------------------------------------
---------------------------------------------------SRCLG--R-
SL--S

PF04598 // ENSGT00530000063218_Domain_1 (606, 794)

LEDFSN----MKEKVQDMVRDLQDLTEQE-RKDVLSCLTRCL--NEDAQLQD---
LEQRVSEVLISG----ELQMEDPAGPLISSLFNDAGILV--EARSEAILDVLDAL-R---
-----------------------------ELSE-EQQLV-AEA------LEKGTLPLLKD
QVES----ILEQNPGE----QPHE--VGCDPE----------------------------
-------------------------------ARNLC-ALYVAVSILLQLSEKPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAIAI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQTSDVG----
-D--VHEGFGT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMEDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCI-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--H-----------------
------------------------------------------------------KW----
-D--VHEGFRA----LKEEVQRETQQVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFIGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----AMEQNFLH-----DKE--GL-------L----S-SLGDED--MTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSL

PF04598 // ENSGT00530000063218_Domain_1 (118, 371)

FLR
TTKNLVRELG-RKGELVPVDSLNSSPRLRPFCLLRKKHKR-YLWPWDTP-L---------
-IPTDFSLLDVLEPG----------------------------C---P--NPEVSHS---
-------------------------------------SPINVWEKVAGG-LTGAVSLS--
-TGLQG--QVTGNS-----------KTTCIS----------ALTVQ-TLWVPP-CTWEML
L-EK------R-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEK
ITKKLVKELG-D-RQLRPVKCLVSATKIHRFSLIQKKK--ARSQFWKRPD----------
-EPLDVSLMHILEPG----------------------------S---S--VPDAAVEV--
--------------------------------------LAAFSYTVVRK-QQA--AGSVN
-AGAEV--GISGGT-----------AVCLGS----------SFQYR-IVSTPH-ETWTEL
Q--K------RKLPDSEPAFLKQCREAG--VNLYVVTDTVEL----LNSPVLQ---DFSS
KKISGKFSNFMDIWV------KG-KAE-AEG--TEMREKKLTV-PKGSV-LAYR-RKQ-L
VF-YSRG-WDILYTADDGD-----QKTFPV----------------PPKHMPQWGWCPG-
---------------------ASHT-------------PMADGEEP---RVLA--RPVIP
AT--PQKGFKL----LQVEVSQEVEA-AKLSKDM-QNVVFSNLRAML--RDCKALQD---
LMDKLEQ----E---PFGHLDGPGGTILTELRKDSCYPE--VGSKCLILYLLEAL-M---
-----------------------------VLSDIQHELL-AQS------MERRILLPQRD
LVRS----ILEPNFNR-----FQN--IPFTLQPELL----A-PLQEEG--LAITYVLL--
-----DECGLEM--ELN-SPRSTW---DPKAKEPLS-ALYGALFLLNQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MPV

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FED
VTRALVRELN-PRGDLTPLDSLIDFKHFRPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDLLEPG----------------------------S------SPS-DLTD--
------------------------------------SGNFSFKNMLDVQ-VQGLVEVPKT
-------VKVKGTA-----------GLSQSS----------TLEVQ-TLSVAP-SALENL
K-KE------RKLS-ADHSFLNEMRYHE--KNLYVVMEAVEA----KQEVTVE---QTGN
AN--AIFSLPSLALLGL------------QG--SLNNNKAVTI-PKGCV-LAYR-VRL-L
RV-FLFNLWDIPYICNDSMQT------FPKIRRVPCSAFISPTQ----M-----------
------------------------I-----------------SEEP---EEEKLIG----
-E--MHEDFKT----LKEEVQRETQEVEKLSPVG-RSSLLTSLSHLL--GKKKELQD---
LEQKLEGALDKGQKV---TLEALPKDV---------LLS--KDAMDAILYFLGAL-T---
-----------------------------ELTEEQLKIL-VKS------LEKKILPVQLK
LVES----TLEQNFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYAW---DPDTRHNLC-ALYAGLSLLHLLSRKSNAL----
--TYCALS---------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----LER

PF04598 // ENSGT00530000063218_Domain_1 (668, 864)

ALDKGHPV---TLEAVPKDV---------LLS--KEAMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------VEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLHLLTKAT-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 783)

MFER
EVKYLLKELG-K-KDLRAVNSPDDATTLCQFKVLRKKKHTFLSMFVEYPD----------
-VPTQFCLMDILQPS----------------------------A---S--FPETSTTE--
--------------------------------------TLVFGITERGT-LGA--GVDVS
-AGLQA--ELLGEI-----------ATSHES----------SLECR-FVKTPL-ATLTEL
I--Q------RKLLKPEPWFLQQCRKRG--ENLYVVTDFVEL----TNSPTLK---DSFS
AKGSGNVSIPWNAFV------KV-KGQ-IGG--LKDRKKMLTL-KPGMV-VGYK-RRP-L
VI-REDG-CEILLHAHDDE-----EDTFQDDFTLHQH-LTLSCVRMLPLPPPTFGQRYPS
RPSP-AT---LKPAKPQLCLFLQPS---SI-----PLLGKRPEIRD---ESILPIGRIEE
-P--ISQNFKA----LQNEVSQEVNALAQLPKDV-QRAVFHNLRAIL--RDRKALQD---
LMDRLEE----D---SLDHLDGPGGTILRILQEKSKERC--FNLKSDILCILEAL-M---
-----------------------------PLSDIQHDLL-AQS------MEMRILSGQRD
LVRN----P---------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 781)

LFAR
DTKSLVRELG-RRGELVPVDSLTSALHLRPFCLVRKKLRR-HPWPWDTP-L---------
-IPTVFSLMDVLEPD----------------------------S---P--VPEVSRS---
-------------------------------------EPIHVQEVVSGA-VTGAMSVS--
-AGLQG--KVMGSS-----------GVTRTT----------TLVVQ-TLWVSP-HTWETL
V-EK------RKLRTPRPSFFRELQNRKERESLYVVTEAVET----MQDTTLQ-S-SINA
A-GAGQLSL-----LGLS-HLQV-QGG--QSH-MAKE-KTVTV-PRGTV-LAYR-VLQ-L
EI-EGDR-WAVLYLPEG-------------------------------------------
---------KLCRD---------------------------TGGGK---QFALNEGE---
E-----PNFQG----LQRQVGAQLQDMATLLPGL-RHTLLDALQELL--KDSQALQE---
LEDTLEQALDTG--V-PAQLGGPGACVLSTLQDPSGSLS--TSKGRAILCVLGAL-V---
-----------------------------VLSDTQRCLL-AQS------LERRILPRQLE
L-----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEN
VTRALAKQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STIFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDMPKT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALEDL
H-KE------RKLA-ADNPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWGRSKIYTDRCTL------FLSSEKPGEEKFT--R-----------------
----------------------L---------------------DA---SFITSLG----
-E--AHEDFKT----LKEEVQRETQEVDKLSQVG-KSSLLSSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LLS--KEAIGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-IKS------TEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLFQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFSFKNMLDAR-VEGEVDMPKT
-------VKVTGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLS-AEHPFLKEMRNRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCI-LAFR-VRQ-L
MV-KGKDEWDIPHIYNDNMQT------FPPGEKPEEKL----------------------
----------------------T----------------------L---ILASDAG----
-E--EHEDFKT----LKEEVQREIQEVERLSQVG-QSSLLTSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LLS--KEAMGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFES
VVQSVVRELD-PRRELIPVDSLQNSANFRPYYLVRRKPP--SSRFWKPR-Y---------
-LCVNLSIKDILEPD----------------------------A---P--EPDLEHGS--
--------------------------------------TFHFFDTIDGK-MQGNMEVAVP
GQW-----KVSGGAA---------VSGSSST----------SMNVR-TLSVDP-NTWDHM
Q-QE------RRLRQPEHRILQQLRSRR--EDVFVVTKVLQT----QEEVEIM---RMRK
QEGSGHFVLPGPMCL------KG-DG---EG--HLMWENKVTI-PAGSI-LAFQ-VAQ-L
VI--RSD-WDIFPFPDEKQRT------FLPSPRGSQPQNT----------FSL-------
-----------------------S--SV----------LRAISDSL---KLLT-DGISEE
SVVTEE--FQV----LRTEVEAGSAALRNMARDL-RQQLLLDLGKVL--CDPPALQD---
LEALLAQGLCGN--GQVKPLEGPAGDILECLVLPSRVLV--QALAAPVFYLLGAL-T---
-----------------------------ALSETQQQLL-AKL------LDKGDLSTQLE
LVEH----LLEQS---T----PWQEQSDVSLSPKLL----G-SNWG-E--EAPAWALL--
-----EKCGLEL--QVG-APQVHW---EPQAQGPTC-ALYASLALLSGLS----------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRK-KD-SRSSIWGQSDY---------
-VPVGFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIVIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSG
VNILGKIS-FWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LVSCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLNDIQHDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DLEAKIPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPT

PF04598 // ENSGT00530000063218_Domain_1 (117, 717)

VFEE
NTRAVVQEMD-PGGDMIAVRSIIDADRFHCFCLVEKKKR-----FLGYQ-Y---------
-DKTDLTLKDILEME----------------------------EGEEL--FDKLDSGLR-
------------------------------VP-EA---ESQLMDNVDSK-GSETLTLLKK
--PIEM------DF-----------NRSWKR----------STTLL-KTW--------IL
D--S------RKLKRELPLSFRSIQNVK--EELYLVTETLET----TKEETVE-------
--SGKCFR--SWIFL------QY-EY------KHQ---MAVSI-SPKKV-LGYR-IKQ-L
VF-PKTE-T----M----------------------------------------------
---IAGLGIFWGGKT-----KSFPE---------------GK------------------
SL--NLEDFRN----MEEKVQDMMRALQDLTEDE-RKEVLSCLTERL--SRDEQLQD---
LQQRVSDVLRSG----ELQIEGPAFLFISSLFNAVGILV--EVHTEAIWDVLDAM-T---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 781)

AFAR
VVRSVVQELD-HGGELTPVDSLQSSTSFQLYCLLGRKSS--SSRFWKHR-Y---------
-TRVNLSIRDILEPD----------------------------A---P--EPAVECGN--
--------------------------------------TFHFHDAMDGK-MQGSVELAAP
GQG-----KLSGGAA---------VSGSSSA----------SMIVC-TLRVAP-NTWEAM
H-RE------RRLRRPEHKVLQQLRNRG--DDVFVVTEVLQT----QQEVEVT---RTQK
QEGSGQFALPGAMGL------QG-RG---EG--HLSQNKMVTI-PAGSI-LAFR-VAQ-L
VI--GSD-WDILFFPDKKQTT------FRPQQEDYRPSYIAGGQ--LQR-SSCLTS----
--------------------------------------TKFLSLRF---KFLS-DGPMED
RLVTT-EGFQG----LQAEVEAWAVGLEGLSREP-CRQLLGALGQVL--RDEAALQA---
LDESLEHGLRGG--LL-ESRDGPVGAVLECLVFSSRRLE--KRLAGPVFYLLQAL-A---
-----------------------------VLSATQHVLL-AEV------LEMGALSGAFK
L-----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFS

PF04598 // ENSGT00530000063218_Domain_1 (117, 486)

VFEE
ITRIVVKEMD-SGGDMIAVRSLVDADRFRCFHLVGEKRT-----FFGCR-H---------
-YTTGLTLMDILDT-----------------------------DGDKW--FDELDSGLQ-
------------------------------GQ-NA---EFQILDNVDSK-GELIVTLLKE
-ITI------SGSF-----------QGFHHQ----------NIKIS-ENRISQ-QYLATL
E--N------RKLKRELPFSFRSINTRE--N-LYLVTETLET----VKEETLK-------
--SNRQYKFWSQISQ---GRL---SY------KHKG-HREVTI-PANRV-LSYR-VKQ-L
VF-PNKE-M---------------------------------------------------
------MR--------------------------------------------------K-
SL--GSEDSRN----MKEKLEDMESVLQDLTEEK-RKDVLNSLAKCL--GKEETRQD---
LEQRVSEVLISG----ELHMEDPDKPLLSSLFNAAGVLV--EVRAKAILDFLDAL-L---
-----------------------------ELSE-EQQLV-AEA------LEKGTLPLLKD
QVKS----IMEQNWDELLASSPHD--KDYDPE----------------------------
-------------------------------ARILC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFAR
STKSLVRELG-RKGELLPVDSLNSSPRLHPFCLVRKKHKL-HPWSWDTP-F---------
-IPTDFSLLDVLEPG----------------------------S---P--VPEVSRS---
-------------------------------------EPIHIREKVTAA-VTGAMSLS--
-TGLQK---VMGSG-----------MVTHSS----------TLALQ-TLRVSP-HTWETL
V-EK------RKLRMPRPSFLRELQSRKERESLYVVTEAMET----LQDTTLQ-S-LSKV
E-GAGQLSF-----LGPS-HFKG-QC---QSH-VAKE-KTVIV-PRGSV-LAYR-VLQ-L
VI-KEDH-WAPMAQEWEAVGFCSPISALA---LMTRKAL--RHSG----C---------S
DLAH-----GICRAS-----LGWGR---------------RTEIQT---AARKAPGE---
E-----PDFLG----LQRWAGAQLHDLATLPPDL-RYSLLGALQELL--RDPQALQE---
LEDMLEQTLYTG--L-LAQLEGPGGSILSTLRDLCGNLS--PSRVRALLCLLGAL-V---
-----------------------------VLSDTQHCLL-AES------LGRCILAQQLE
LVAS----ILEGNFNQ-----MEE--TAVSLRQDVL----S-SLQSED--AALTLSL---
----VQSCEL-E--QGP-SLQLVW---DPEALLQLS-ALCGALAGLQLLACPGPRPS---
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTMFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------N------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVRGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALESL
H-EE------RKLA-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWDIPHICNDSMQT------FPPEEKPGEGKCA--------------------
--------------------------------------------L----IQASDVG----
-E--VHEDFGT----LKEEVQRETQEVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHKV---TLEALPKDI---------VLS--KEAMDAVLYFLGAL-T---
-----------------------------V------------------------------
-

PF04598 // ENSGT00530000063218_Domain_1 (782, 864)

-ES----MMEQNFLQ-----DKE--GIFPLQPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDALPHLC-ALYAGLSLLHLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEK
VVKNVIKEVSGIKGDLIPVDSLRNSTSFRPYCLLSRKPP--SSLIWKPR-Y---------
-TCVDLSIKDILEPN----------------------------A---P--EPEPECLG--
--------------------------------------SFKVSDVVDGN-IQGKVTLSGT
GEG-----RISGGAT---------VTDSSSA----------SMNVR-ILRVTQ-ETWETM
Q-HE------RHLQQPEKKILQQLRSRG--VDLFVVTEVLQT----KEEVQIT---ETHS
QEGSGQFTLLGAVCL------QG-EG---KG--HQSRKKMVTI-PAGSI-LAFR-VAQ-L
LI--GSK-WDILLVSDEKKRT------FE-PSSGDRKAVGQRHH--VLNVLA--------
--------------------------TM----------RRYTSEQF---RLLS-DGIDEE
EVVE--ADFQG----LYVEVKSCASELESLDMEL-RQQLLENIGSIL--QDQPSMEA---
LTDSLEQGLCSG--GQVQPLDGPAGCILECLVLDSGELV--PELAAPVVYLLEAM-S---
-----------------------------VLSETQKLLL-AKA------LETTVLSKQLE
LVKH----VLEQS---T----PWQEQCSVSLPSVLL----G-DCWD-E--EDPNWVLL--
-----EECGLRL--QVE-APQVHW---EPTSLTRTS-ALYASLFLLSSLGQNPC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPATL

PF04598 // ENSGT00530000063218_Domain_1 (119, 489)

HE
LSKEAVKMLG-G-KDLKPVKSLSDATKFHEFNILQKN---PQSWFWEPRED---------
-IPTGFSLLKILEPG----------------------------V---S--DPETVESV--
--------------------------------------PVPIRDTVVQK-VNA--DVGVK
-IGVEG--HVSGEF-----------AQSSGY----------DIMVR-GISIPE-PNLESL
Q--N------RRLKDPEPTFLKNCRING--DNLYVVTEAFEL----IKDTTLE---DSSS
V---------------------------GEW--QKERKRTMTV-PKGTV-VAYR-RKQ-L
VI-KNKS-CEVIQEGGDGG-----------------------------------------
-----------------------------------------------------KERKVEE
-P--FHQDFKC----LEKEVSEQTRLLAELSKDV-QDVVFYSILPML--GDREALYD---
LMDMLEL----D---QLGHMDGPGGAILDKLRQDSRPLL--VNPKKLFLYLLQAL-A---
-----------------------------VLSDIQLYLL-AQS------MEKRILLQQRE
LVKS----ILQPNFKY-----PWS--IPFTLQPELL----A-PLQGEG--LAITYSLL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPMS-ALYGTLSLLQQLAEPG------P
RPVDA------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPSADPTD--
------------------------------------SGNFSFKKTLDAR-VEGEVIVQKT
-------VKVTGTA-----------GLSRSS----------TLSMQASGEE-E-LVLISR
G-ER------GKLS-AEHPFLKEMRNRG--ENLYVVMEVVET----AQEVTLE---RASK
AE--GCFSLPFFAPLGL------------QG--SIDHKEAVTI-PKGCI-LAFR-VRQ-L
MV-KGKEEWDIPHICNDSMQT------FPPEEKPEEKFT---------------------
---------------------------------------------F---ILASDAG----
-E--EHENFKT----LKEEVQREIQEVEKLSRVG-QRSLLTSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LVS--KEAMGGILYFLGAL-T---
-----------------------------ELSEAQQKLL-IKS------MEKKILSVQLK
LVES----TMEHSFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 510)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q-QE------RKLA-ADHPFLKEVRGQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFSPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGG----------------------------
------------------------------------------------------------
-D--VHEGFRT----LKEEVQRETQQVEKLSQVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPRDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKD--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLSKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFAR
DARSVVRELG-RRGELVPAD-LNSAPHLRPFCLLRKKHRR-HPWPWDTA-F---------
-IPTDFSLMDALEPS----------------------------S---P--IPGTFSC---
-----------------------------------VISNDNFKEMVAGA-VTGAMSVS--
-TGMLV--QVTGNS-----------GVIHSF----------TLTVH-TLMVSP-NTWETL
M--K------RKLRTPKPLFLRELQCQKEKESLYVVTEAIET----IHDTMLQ-S-LSNT
E-GAGRLAI-----LGPG-HLKV-QGS--EPH-GQRE-DSDYP-PGGTV-LAYR-VLQ-L
VI-KEDC-WGRAGKGAGAT-----------------------------------------
-----------CKCG-----AGRGR---------------GR-------LFLSGLSP---
QP--DSSTFWQLLKGSEVQKGPRERRKGRREGEL-QHLLLSALQELL--QDPRDLQE---
LEDTMEQALDTV--V-LGQLVGPGGSILSTVRSPSGSLL--TSKGRAILCTLGVL-V---
-----------------------------VLSDTQHCLL-TQS------LEKGIMPQQME
LVVS----ILEPNFNQ-----MEE--TTFSLPLEVL----S-SVQSED--AVLSLSLV--
-----ESCGLEL--QAP-SQQLTW---DPDVVPQLS-ALYGSLAGLQMLAAPS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MVS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEG
MVRSVVRELD-RSGELIPVDSLQSSTGFRPYGLVSRKPS--SSWFWRPR-Y---------
-KCVNLSIKNILEPD----------------------------A---P--EPGLECSG--
--------------------------------------PFLFYDAMDGK-LQGKVELATP
GQG-----KISGGAA---------VSGSSSA----------SMDVC-TLRVDP-NTWETM
H-QE------RRLRQPEHKILQQLRSRG--DDVYVVTEVLQT----QKEVEVT---RTHK
QEGSGQFALPMAMCV------QG-EG---QG--HLSRKKTVTI-PSGTI-LAFR-VAQ-L
VI--GSD-WDIHLFPDKKRRT------FQPPTTGPKPSGSADSG--GQDIFGL-------
-----------------------LL--K----------GSICGHRK---FLTA-DGPSEE
WEVTDN--FQG----LKAEVAARSVELEHMEREL-SRQLLGGLAGVL--QNKPALQA---
LEESLEQGLCC---GQPKPLAGPESAVLECLVFPSGALV--EELAIPIFYLLGAL-S---
-----------------------------VLSETQCMLL-AKA------LDTEALPRHCE
LVGS----LLERA--------LWHEYSTMSLPPRLL----G-SNWH-K--GAPAWVLL--
-----EECGLVL--QVD-GPHVCW---EPQAQGPTC-ALYASLVLLSRLSQESC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPT

PF04598 // ENSGT00530000063218_Domain_1 (117, 795)

VFES
ITRAVVKEMD-TSGEMIAVRSLGDADKFHCFYLVKKRRR-----FFGYQ-Y---------
-DKTNLTLKDI---L----------------------------ESEVP--FDMVVPEFQ-
------------------------------GQ-GD---NFEILDVVDSK-GSLTVRFHPQ
-MTFKI------AF-----------HIFQEK----------NIKLE-KSEIPQ-EFLDSL
K--N------KKLKKELPPSFQSIQAKR--EDLYLVTETLKT----KKTDTLK-------
--YETQFDFQSLLKM---FGF---QC------EHKR-QKEVTI-PAEKV-LAYR-VKQ-L
VF-PSAE-RM--------------------------------------------------
-------DICFLGKT-----SSFPE---------------EKDGGS------SWLG--K-
SL--SLENFQS----IKERVQDMVRVLQDLTPEE-QKEVLNCFTKCL--SSDEELQD---
LEQRVSEIQCSG----ELQMNSPVNSLISSLFNAAGVLI--EARAETIWDVLDAL-T---
-----------------------------ELSEY-RRFV-AEA------LDKGTLLHMKD
TVEP----ILKKNWGE----GPLD--VSCDPE----------------------------
-------------------------------AWTLY-AFYVVVSILLQLGEKPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------

PF04598 // ENSGT00530000063218_Domain_1 (372, 864)

KLT-AEHPFLKEVRSRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GAFSLPFFAPLGL------------QX--XXXXXXXXXX-XXXXX-XXXX-XXX-X
XX-XXXXXXXIPHIYNDNMQT------FPPGDRPDEEKIT--------------------
-------------------------------------------------VRGSVIW----
-E--AHEDFKT----LQEEVRRECQEVQKLSAAG-RGSLLSSLSKLL--GKKQELQD---
LEQTLEGALDKGHEV---SLEALPRDV---------VLS--KEAMGAVLYFLGAL-T---
-----------------------------ELSEVQQKLL-VKS------VEKKILPVQLK
LVET----TLGHNFHE-----DKE--GVFPLQPELL----S-SLGEDE--LTLTEALV--
-----GLSGLEV--QRS-GPEYTW---DPDSLPHLC-ALYAGLSLLQLLTKTA-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPYSFDW
VCKDVVKKLQ-G-KDLCPVKRLSDATKFRQFEILQKTA---QSLFWKTED----------
-IPVGYSLLQILEPN----------------------------F---P--VPDPEVSA--
--------------------------------------PIPLKCTVSQK-LKG--NLGVN
-AIAEG--SVSAEF-----------AHSSGY----------DIEVQ-CTSIPA-SKLEIL
Q--N------RKLVEKEPSFIKDCRIGR--KDLYVVTEAFEV----TRGTVLE---DSSS
VSLLGKVLTPQFAK--------------V-W--NGETKDSVPI-LKGAV-VAYK-KKQ-L
VI-ENDT-CGEQTWGL--------------------------------------------
------------------------------------------------------------
------------------------------------------

PF04598 // ENSGT00530000063218_Domain_1 (643, 864)

-LPML--GDRDTLYD---
LMIMLEL----G---QLGHMDGPGGVILDELRK---DSW--NVLKDLILYLLHAL-M---
-----------------------------VLSDTQLSLL-AQS------VEKQFLLQQRQ
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYGLL--
-----SECGLQM--DLN-NPRSTW---DLEAKMPMS-ALYGSLSFLQQLVEPGPSP----
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPHSFDW
VCKDVVKKLQ-G-KDLCPVKRLSDATKFRQFEILQKTA---QSLFWKTED----------
-IPIGYSLLQILEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PIPLKCTVSQK-LKG--HLGAK
-VVAEG--GASAEF-----------AHSAGY----------NIEVQ-CTSIPA-SKLEIL
Q--N------RKLVDKEPSFVKDCRIGA--TDLYVVTEAFEV----TKGTVLE---DSSS
VNLQGKVLTPQFGKV------WD-RDG-E-W--QRERKDSVPI-LKGAV-VAYK-KKQ-L
VI-ENDT-CGEQLWGISGCGV---SHDLTLLFSPD-------------------------
-----------------------------------YRPGVERDSPM---CVSSFLGRIEE
-P--LY-

PF04598 // ENSGT00530000063218_Domain_1 (608, 836)

-FQH----LQNEISEKTWKLAILSKDV-QEVVFSSLLPML--RDKEILYD---
LMIMLEL----G---DLGHMHGPGGVILDELRK---DPW--IGLKDLILYLLHAL-M---
-----------------------------VLSDTQLNLL-ALS------MEKRLLLQQRE
LVKS----ILQQNFKY-----PWN--IPFTLQPELL----A-PLQGEG--LAITYE----
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------M

PF04598 // ENSGT00530000063218_Domain_1 (456, 864)

NHKEAVTI-PKGCV-LAYR-VRQ-L
MV-NGKDEWGIPHICNDNMQT------FPPGEKPGEGKFI--------------------
--------------------------------------------L----IQASDVG----
-E--MHEDFKT----LKEEVQRETQEVEKLSPVG-RSSLLTSLSHLL--GKKKELQD---
LEQMLEGALDKGQEV---TLEALPKDV---------MLS--KDSMDAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTRHNLC-ALYAGLSLLHLLSRDS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MLER
ISKNLVKEIG-S-KDLTPVKYLLSATKLRQFVILRKKKD-SRSSFWEQSDY---------
-VPVEFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DMGVN
-VGIEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---DSSS
VNILGKIA-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDGYEISAM-VGYCAAR-SEGLLPSFHTISPT
LFNA-SSN-DM---KLKPELFLTQQ---FL-----SGH--LPK-EQ---VHILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVMFYSILAML--RDRGALQD---
LMNMLEL----D---SSGHLDGPGGAILKKLQQDSNHAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDFQHDLL-ACS------MEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DVEAKVPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------AGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAIAI-PKGCV-LAFR-VRQ-L
MV-KGKEEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFGT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 794)

IFEE
ITKTVVRELD-SGGNTIAVRSAIDADRFHCFYLVREKQS-----FFGSR-Y---------
-CKTDLTLKDILESE----------------------------NGERP--IDEVDSVS--
---------------------------------------PVMEDLIPAQ-REFSVKLPKT
-ITSRG---MAGWS-----------QGTQGQ----------EIKIL-VNRIPQ-QYLDSL
V--D------RKLKKKLPRIFELVQARG--EHLYLVTEALVT----VNEETLR-------
--RERQFEFNSWMDWNI-FGFAY-KG------SINH-QTSVTI-PSQRV-LGYR-IMR-L
PF-PNPE-KR--------------------------------------------------
----NGLDICFSDET-----KSFPE---------------AELQAQGLQLSLKAAS--V-
SS--NLEDFRN----MKEKVQDLRRSLQDLTKQE-RTDVLSCFSKFQ--GNDGHLQD---
LEERVRAQMEL-----------VLISLISLPQVSEVLVS--EARADAIQALLDAL-M---
-----------------------------ELSEEYQQFV-FEA------LEKGMLPQLVE
EVES----TLEKKW----------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSHS

PF04598 // ENSGT00530000063218_Domain_1 (118, 489)

FDW
VCKDVVKRLK-G-KDLRPVKCRSDARKFRHFEILLKTP---QSLFWKSED----------
-TPVEYSLLQILEPN----------------------------L---P--VPEPEVLD--
--------------------------------------TIPLKHIVYQK-LKG--NVGVN
-AIAEG--NVNTEY-----------VQSYGY----------DIEVQ-CIGIPN-SKLESL
Q--N-------KLLDKEPSFVKDYRMGR--YSLYVVTEVFEV----TKCEMKE---NITS
AGTTVDAAIAQVVTG-------Q-AQ--GQW--ERKTMDSVPI-QKGTV-VAYK-KKR-L
VI-ENDT-CD--------------------------------------------------
------------------------------------------------------------
--------FKR----LQNEVSQITQELAMLPKDA-QEIVFSNLQSML--SNREHLND---
LLSMLEL----D---QLGHMDGPGGAILDQLRQDSIPPW--IDLRN--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEG
VARSVLLELD-RHGDLIPVDSLRNATSFQPYCLLSRKPS--TSWFWKSR-Y---------
-EAVNLSIRDILEPD----------------------------G---P--EPELQRGG--
--------------------------------------LFHFHDTVDGQ-LHGSVELA-A
GQG-----KISGGAT---------VSGSSSA----------SMEVC-SLRVDL-SVWGVL
Q-KE------RHLRKPEHKLLQQLRNQR--ANVFIVTEVLQT----QQEVEVN---CTRK
QEGSGHFSLPGAVCL------QG-QG---QG--HLNWKKTVTI-PSGST-LAFQ-VAQ-L
VI--DSE-WDIIFFLDRRQST------HRTAPGARLLP----------------------
--------------------------------------PSYLSSLM---VHLA-DGLEGW
ALPTED--FTG----LRTEVETQAELLEPLSCGL-RRQLLEALGSLL--PDMLALKA---
LEEALEQGLSS---KRVEPRDSPEGAVLECLVLHSRELA--TEPTAPIYYLLGAL-A---
-----------------------------ALTETQHLLL-AQA------LSTRSLSGQLE
LVES----LLEQS---S----PWQVPKEVSLP---L----R-SSWC-E--DTPAWVLL--
-----EECDLEL--QVD-SPQVCW---KPQAQGPTC-ALYAALVVLNRLAQEPCEW----
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MLA

PF04598 // ENSGT00530000063218_Domain_1 (117, 898)

VFEK
IARAVVQHVD-AGGDMIAVRSLIDADRFHCFYLVKERRR-----FFGYQ-Y---------
-DKRDLTLDIL-EMD----------------------------KGEGL--FDKLVPGLQ-
------------------------------GQ-KV---KSQVMDSVDSK-GSLTVKLPKE
-KTLDD------IL------------QSPEQ----------GIGLS-KTWILQ-KFLDSL
K--N------KKLKRKLTPMFQSIQAMR--EDLYLVTETLKT----TKTVILK-------
--SEKQYIFW--DQM---FWL---RY------EHKH-QTEVSI-TPQKV-LGYR-VKQ-L
VF-PNAE-SM--------------------------------------------------
-------ETGLGI--------SFSG----------------RKEKS------FPEG--K-
SL--SLEDFPS----VKERMQDMVRVLQNLTE-E-RKEVLSCFTKCL--SKDEELQD---
LERRVSEVRCSG----ELQMEGPQ-VLSCNLFNAAGILI--EEHTEAISDFLDDL-M---
-----------------------------ELSEE-GQLV-AEA------LVKGTLPLLKD
KVEP----ILEQNQGE----QPRD--VGCDPE----------------------------
-------------------------------ARTLC-ALYAVVSILLQLGENSTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSRSS----------TLEVQ-TLSVSP-KALETL
H-QE------RKLS-AEHPFLKEMRNQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCI-LAFR-VRQ-L
IV-KGKDEWDIPHICNDSMQT------FPPGEKPEEEK----------------------
----------------------F---------------------IF---IQASDVG----
-D--IHKDFRT----LKEEVQRETQEVEKLSQVG-RSSLLTSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LLS--KEATGAILYFLGAL-T---
-----------------------------ELNEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLQPNLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSILQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------CGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLA-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWDIPHICNDSMQT------FPPGEKPGEEKFI--------------------
---------------------------------------------L---IQASDVG----
-E--MHEDFKT----LKEEVQRETQEVEKLSQVG-QSSLLTSLSNLL--GKKKELQD---
LEQTLEGALDKGHEV---TLEALPKDV---------LLS--KDAMGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKKLLPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQLLSKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSC

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFQR
ISKSLVKEVG-S-NDLTPVKCPIRATKLRQFAVLQKMN-NSRSVFWEKYDY---------
-VPLQFSLSDILESS----------------------------S---S--VSDNDVNG--
--------------------------------------PLYFCDTMIQK-YEA--GIGVN
-VGGEL--NVSGEA-----------SADQGG----------SLGYQ-IVTISA-PNLEVF
Q--K------RKLLHPEPEYLKDCRRRG--GNLYVVTDAVEL----ISDAVLR---DNSS
MDLFGKIS-LWITYG------KG-QGQ-GKI--FRKKEKALTL-KKGMV-MAYK-TKQ-L
IF-EEKD-RTIL-ITDDDE-----RSTFQDVYRISER-LGYC---------GSFTTISST
FFNA-SSN-DI---KLKLEAN-L-------------VG--MRKGDS---DLILLLGRIEE
-P--FWQNFKH----LQVEVSENIEALAQLSKDV-QGVVFYSILAML--RDGEDLQD---
LMYMLKL----D---SSGHLDGPGGTILKILQQDSNHAL--SKSKEAILYLLEAI-M---
-----------------------------VLSDIQHDLL-AYS------MEKRILLQQQE
LVRS----ILEPNFIY-----PWS--IPFTLKPELL----A-PLQSED--LAITYGLL--
-----EGCGLRM--ELD-SPRSTW---DLAVKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFEL
VVRSVLQELD-QRGDLTPVDSLQKSTSFRPYYLLSRKHP--SSWFWKPR-Y---------
-TCVNLSIKDILEPD----------------------------A---P--EPEPECGG--
--------------------------------------PFRIDDAVDGK-AQGSVKLEAP
GQG-----KISGGAV---------VSGSSSV----------SIIMH-TLCVAP-NTWETM
H-RE------RRLRQPEHKILQQLRSHR--NDVFVVTEVLQT----QEKVQVT---QTRK
KGASGQFALLGAMCL------QG-EG---EG--HLSKKKMVTI-PAGSI-LAFR-VSQ-L
LI--GSN-WDILLVPDEKKRT------FEQPPKGHRNAGDQQQH--T-------------
---------------------------K----------LRFIHEHL---RFLS-DGTPGE
GVVSED--FQG----LGVEVEAGSSELKHLEMEL-KQQLLVNIGRIL--QDLPSLEA---
LEASLEQGLCNG--GQVQPLDGPAGNILQCLVLPSGELV--PQLAAPVFYLLGAL-T---
-----------------------------VLNETQYQLL-AKM------LETGVLSEQLE
LVEN----LLEQS---T----PWQEQSSVTLPPRFL----G-GSWD-E--DAPAWVLL--
-----EECGLEL--QMD-APQVHW---KPNAQGPVC-ALYASLALLSRLSQEPC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q-QE------RKLA-ADHPFLKEVRDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFSPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDSMQT------FPPGV----------------------------
-------------------------------------------------IQASDAG----
-D--VHEGFRT----LKEEVQRETQQVEKLSRVG-QSSLLSSLNKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPGDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKD--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYASLSLLQQLSKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEG
VIKSVIRELD-HRGKLIPVDSLRSSTSFQPYCLLARKLS--RLWFWKPR-Y---------
-KCINLSIRDILEPN----------------------------D---P--EPDVKCDG--
--------------------------------------PFHVCDFMDGQ-LQGSVELAPP
GQV-----QLAGEAT---------VADNLST----------SMNVC-TLRVVP-NTWDTM
R-QE------RRLRQPQHKVLEQLRNCG--NDIFVVTEVLQT----QKEVTVT---WIYK
QEGSGQFSLPGALSL------QG-Q-----G--HLRRKKTVTI-PSGSI-LAFE-VAQ-L
VI--GPD-WDVLLFPNKKQRT------FKQSKKNHK------------------------
---------------------------------------PTSSAGS---KIQS-DGFGED
LVAVT-EDFQG----LLAEVGTQAEGLRGLSRGL-CDQLLAGLVRVL--QEEPALQT---
LEEALEQGLFCG--WV-APLEGPVGTVLECLVHTSRALE--EQLARPVLYLVDLL-T---
-----------------------------GLSETQLKLL-TKV------LETGELSRPFK
LVQS----ILEQS---T----PWQERRAVSLPQGLL----E-GSWD-A--EAPAWVLL--
-----EECGLEL--QVD-DPQVCW---EPEARDHTC-TLYACLALLLCLSEDPC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEK
ITKKLVKELR-D-RQLRPVKCLVSATKIHRFSLIQRKK--ARSQFWQLPD----------
-EPLDVSLMHILEPG----------------------------S---S--VPDAAVEV--
--------------------------------------PAAFSYTMVRK-QQA--AGSVN
-AGAEA--GISGGT-----------AVCQGS----------SLQYR-IVSTPH-ETWTEL
Q--K------RKLPDSEPAFLKQCREAG--VNLYVVTDTVEL----LNSPVLQ---DFSS
KKISGKFSNFMDIWV------KG-KAE-AEG--TKMRKKQLTV-PKGSV-LAYR-RKQ-L
VF-CHRG-WDILYTADDGD-----GDSFPV----------------PQKHMPQCGWCPG-
---------------------EFPT-------------PMADGEEQ---PVLA--CPVIP
AT--PQKGFKL----LQEEVSPKVEA-AKLSKDM-QNVVFSNLRAML--RDRKALQD---
LMGKLEQ----E---PFGHLDGPGGTILTELRKDSCYPR--FGSKCLILYLLEAL-M---
-----------------------------VLSDIQHELL-AQS------MERRILLPQRD
LVRS----ILEPNFNG-----FQN--IPFTLQPELL----A-PLQEEG--LVITYGLL--
-----DECGLEM--ELN-SPRSTW---DPKAKEPLS-ALYGALFLLNQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGSFGFKNMLDAR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
H-GE------RKLA-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHIYNDNMQT------FPPGERPGEEKF---------------------
--------------------------------------------IL---IQASDIG----
-D--VHQDFRT----LKEEVQRETKEVEKLSHVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEATDAILYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------VEKKILPLQLK
LVES----TMEQNFLQ-----DKE--GVFPLQPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------AGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RRLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACLSLPFFTPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHKGFRT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PHGDLTALDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDLLEPG----------------------------S------APS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALETL
H-EE------RKLA-ADHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWDIPHICSDTMQT------FPPGEKPEEKF----------------------
--------------------------------------------TL---IQASDVG----
-E--AHEDFRT----LKEEVQRETHEVEKLSRRG-QSSLLSSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LLS--KEAMGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MERKILPVQLK
LVES----AMEQNFLQ-----DKE--GVFPLRPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPHLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFAR
VVRSVIQELD-QSRELVPVNSLQNSSSFRPYCLLRRKPT--SFWFWTPR-Y---------
-TCVNLSIKDILEPK----------------------------A---P--EPELERDG--
--------------------------------------PFHFSDAVDGR-VQGSVELAAP
GQG-----KISGGAA---------VSGSSST----------SMNVC-TLRVAP-NTWEAM
R-QE------RHLRQPEHKVLQQLRSCR--DDLFVVTEVLQT----QEEVQVT---RTHK
QEGSGQFALPGGMCL------QG-ES---QG--HLSQKKMVTI-PAGSI-LAFR-VAQ-L
LI--GSD-WDILLFPDNKKRT------FELSPTDHSKARVQQHT--FSLS----------
--------------------------ST----------LRSIYNRL---KFLS-DGTPED
WVLS--KDFQG----LRSEVEAGSMELERLEVEL-RQQLLENLRRVL--RDQSILQA---
LEASLEQGLFSG--GQVEPLDGPAGTILECLALPSGVLV--PELAASVYYLLGAL-T---
-----------------------------ALSETQHQLL-VET------LETGALPGHLE
LVEH----LLEQS---T----PWQQRSVVALPPGHL----G-SNWG-E--AAPAWVLL--
-----EECGLEL--QVD-MPQVRW---EPEAQGPTC-ALYASLALLSGLSQEPC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTALDSLIDFQRFHPFCLVLRKRK--STLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------S------SPS-EPTD--
------------------------------------AGSFSFKNMLDAR-VEGEVDVPRT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALESV
H-KE------RKLA-ADHPFIKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTL-PKGCV-LAFR-VRQ-L
IV-NGTDEWDIPHICSEGTQT------FPPGGKHMSSPPHGDG-----------------
----------------------L---------------------AA---TSAVLTG----
-E--VHEDFKT----LKEEVRRETQEVDKLSRAG-QGSLLSSLSNLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------VEKKLLPVQLK
LVES----TLEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYASLSLLQLLARSP-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MVIIF-Q
G

PF04598 // ENSGT00530000063218_Domain_1 (122, 864)

SKSLLRQVG-K-EDLKPVTNLKSAKKFHHFNMLRSKK-SAFSSFWKQPD----------
-IPVEFSLLDILDPS----------------------------S---P--VPXXXXXX--
------------------------------------XXXXXXXXXXXXX-XXX--XXXXX
-XXXXX----XXXX-----------XXXXXX----------XXXXX-XXXXXX-XXXXXX
X--X------XVLLKPEPWFLEQCRKRG--DNLYVVTETVEL----INSPELS---IESG
RVVG---KILHNPYI------KG-QGH-IDG--DKKKQQLLTL-PEHTV-MAYQ-TKQ-L
II-KEDE-ILLI---KDKK-----QKTFSDXXXXXXX-XXXXXXX-XXXXXXXXXXXXXX
XXXX--XX-XX---XXXXXXXXXXX---XX-----XXX--XXXXPG---GEILPIEIIEK
-P--VSQNFKR----LQDEISSIMEDLSSFSKDI-QDILFRNILVML--GDRGALQD---
LQDKMEQ----F---PQGDLDGPGGIILNELRKNFKPSW--ANPGFCIPYMLEAL-M---
-----------------------------VLNDTQHELL-AWS------MEMKILVHQRE
LVRS----ILEPNFKY-----TSR--IHFSLKPELL----T-PLQDEG--VTVTYQLL--
-----EECGLMI--DLN-SNSSSW---DLESKMPLS-ALYGCLSLLQQLAVP--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEE
VVKSVIKEVD-RKGELIPVDSLRNSTSIRPYCLLSRKLS--SSWFWKPR-Y---------
-RCVNLSIKDILEPN----------------------------A---P--EPEPECCG--
--------------------------------------RFCVSDAVDGN-IQGRVALEST
GQG-----KISGAAA---------MSGSCSA----------SINMC-LLRVTQ-NTWNVM
Q-HE------RQLQTPEHKILEQLRSRG--DDVFVVTEVLQT----EEDVQVT---QTLS
KEGLGQFALPGAVCL------QG-EG---KG--YLNQKKMVTI-PAGSI-LAFR-VAQ-L
LI--DPK-WDILLIPNEKKRT------FELPPSSHRREDGQRQH--AFNLLA--------
--------------------------TL----------RSM-GERL---KLLT-DGTHEE
QVTR--EDFQG----LRTEVEAASTELGHLEMEL-RQQLLMDIGRIL--HDQPSMEV---
LEASLEQGLCHG--RQMEPLDGPAGSILEYLVLPSGELV--PELAAPIFYLLGAL-T---
-----------------------------VLSETQQQLL-AKA------LETTVLSKQLE
LVEH----ILEQS---T----PWQEQRFVSLAPRLC----G-NSWD-E--EAPTWVLL--
-----EECGLTL--QVD-TPQVHW---EPKSQGPTC-ALYASLALLSSLSQKPC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAIAI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFGT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 468)

PFED
VTRLVVGELD-SGGDMIAVRSAIDADRFNCFYLVAEKKN-----VFRAQ-Y---------
-YPTSLTLQDIMEPN----------------------------EGEKL--PDEVDSKPS-
------------------------------GQ-ND---EFGIKDKAGSM-AGCIVKVLKT
-TTIFR------SP-----------QKSQDQ----------EARVS-VHPISQ-QQLDSL
V--E------WQLKKQLSHTFESLRAKK--DHLYVVTEALVN----EE--TLK-------
--RGQLA-LKSQLFL------QYAHF------KREQ-HRSVTI-PPNRG-LESR-FSHQD
HF-RKSE-G---------------------------------------------------
-------MISFTAKT-----NSFPE---------------GK------------------
SL--SLEDSQN----TKAKVQDLEGDLQDT---------TSCPTECL--RE-GGLQD---
LEER--------------------------FFYDAGMLV--ESRVEAFQVLLDAL-----
-----------------------------GLPREYQQLL-LGV------FEEKVLPLLLG
EGEH----VLEKNGGAQ--SCTHD--GVPGPE----------------------------
-------------------------------EQTLR-AFYVAVSILLQLQEWPTFVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------N------CPS-DPTD--
------------------------------------SGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALENL
H-KE------RKLA-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWDIPHICNDSMQT------FPPGEKPGEAKFL--------------------
---------------------------------------------L---IQASDVG----
-E--MHDDFET----LKEEVQRETHEVEKLSKVG-QSSLLTSLSNLL--GKKKELQD---
LEQTLEAALDKGHEV---TLEALPKDV---------LLS--KDAMGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKKLLPMQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSFLQLLSKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSL

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FGR
TSKNLVKELG-D-KDFRPIQNPLSANKFCQLKLLRKKR-RTLS----QPD----------
-VPVDCTLTDILEPS----------------------------P---S--VPVPVMTE--
--------------------------------------KFVFIDKMVWK-GAA--EVDVT
-AGLEV--CVSGKA-----------NQSYEC----------SLEVQ-SVTISP-CDWEDL
Q--K------RKVLDQEPSFLKECRTRG--DNLYAVTEAVKL----INRTVLQ---DSSS
VNATGKFSVPWSFYA------KS-TGD-GSG--LKVRERTLTL-PQGTV-MAYK-RKQ-L
VF-RENG-RAILLISDDDK-----RKTFPEDEFLSWA-LCQLRV---EAL------HSPA
HSFT-HSRISFSPPNLLLPPPLTPQ-PLLS-----TRTVLAYYDSS---ILRVQTHRPQK
CF--WLADFKS----LQNEVSREMEAVAELPTDI-QDALFHTILAKL--KDQGALQD---
LTDMLDG-----------NLWIHTGSFLSEMQEDSRNVW--LESK-HIIYLLEAL-L---
-----------------------------VLSDIQHELL-AWS------MEKKILPQQRE
LVKS----ILEPNFRN-----LWN--IPFTLDPKLL----A-LLQEEG--LVVTFGLL--
-----QECGLRV--APD-NPKGTW---DLEAKKPLS-ALYGSLSVLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVKSVVRELD-HGRELTPVKSLQTSDRFQPYCLLGRKPS--SSWFWRPR-Y---------
-TCVDLSIWDILEPS----------------------------A---P--EPAVERGG--
--------------------------------------PFYFHDTMDGQ-LQGQVELAAP
GQG-----KFSGGAA---------VSGSSSA----------SMNVC-TLRVAP-NTWDAM
H-LE------RRLRQPEHKVLQQLRSRG--NDVFVVTEVLQT----QKEVEVT---RTHK
QEGSGQFALPGAVSL------QG-QG---QG--HLSRKKTVTI-PSGSV-IAFR-VAQ-L
VI--GSD-WDILLFPDKKQRT------FRPLREGHSASHGADGQ--PPQFSRLVSG----
--------------------------------------MSFPSEHL---KFQS-DGPAED
QLVTT-EDFQG----LQAEVDAWAAGLEALSREP-CRQLLGGLGQVL--QDEPALQA---
LEDSLEQGLCGG--LV-EPQDGPAGAMLECLVLACRRLE--REVAGPIFYLVQAL-A---
-----------------------------VLNETQHVLL-AKV------LETGALSGALT
LVGS----LLEQS---A----PWQERRAVSLPPTLL----G-SSWG-S--EAPIWALL--
-----EECGLEP--QVG-TAQVCW---EPEAQSCTC-ALYACLALLLRLSQLC-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------

PF04598 // ENSGT00530000063218_Domain_1 (372, 864)

ALFKPEPWFLKQCRERG--DNLYVVTETVEL----INGPELS---VESG
RKWLGKFSISQNPYI------KG-QGH-IDG--DKKKQQSLTL-PEHMV-MAYQ-TKQ-L
II-KEDE-ILLI---KDKK-----QKTFSDFSSRK-------------------------
-------------------------------------------LCR---REILPIQNIEE
-P--ISQDFKK----LQDEISRRMKELSNFSKDI-QDILFHNILVML--GDRGALQD---
LQDMMEQ----F---PQGDLDGPGGIILKELRNNLQNSW--DYPLSCISYMLEAL-M---
-----------------------------VLNDTQHDLL-AWS------MEKKILVYQRE
LVRS----ILEPNFKY-----PWR--IPFTLKPELL----T-PLQDEG--VTVTYKLL--
-----EECGLMI--DLN-CNRSFW---DLEAKVPLS-ALYGCLSLLQQLAVA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 371)

VFQD
TTQALVRQLD-PSGELIPVTSIIDVSCFRPFCLVKRTR----TSFWGVR-Y---------
-VKTDFSLRDILEDG----------------------------P---E--LPEPSKD---
-------------------------------------PVIKIGENTENT-MATGVTA---
-ADFQIPVMITFSA-----------GGSDYN----------YLEIQ-KLSIVQ-EL-ES-
L-RK------R-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------FWEL

PF04598 // ENSGT00530000063218_Domain_1 (625, 864)

EALSLLSQDA-QDAIFHTILNML--GNQEALQD---
LMDELDR----N---PWDPPDSFGGKILNEMQEDIRDLW--IQERFHITYLLEAI-M---
-----------------------------VLSDTQRDLL-AQS------MKKRILLQQQE
LVRS----ILEPNFKY-----FKD--IPFTLKPELL----A-TLQDED--LAITYGLL--
-----QECGLNM--ELN-SPSSTW---DLEDKQTLS-ALYGTLSLLQRLTVS--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSIFEE
ITRIVVKEMD-AGGDMFAVRSLIDADRVHCFHLAEEKRT-----VFGYG-----------
--DK-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDSK-GKLI------
--------------------------V---------------------------------
---K------LKLKRELPFSFRS

PF04598 // ENSGT00530000063218_Domain_1 (384, 795)

INRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNEIFQ---SHL---SY------EHKG-QREVTI-LPNRV-PSYR-VKQ-L
TM-NKQR-LMGNRMGRP---------------KHTSE--------------V--------
GGGIQPDSVSLGDKT-----KSFP------------------------------EG--K-
SL--GSEDSRT----MKEKLENVESVLQELTEDK-RKDVLNFLTKCL--GREELWQD---
LEQKISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--GARAEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHD--VDCDPE----------------------------
-------------------------------ARIPC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGSFGFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALETL
Q-GE------RKLV-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVDHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKPGEEKF---------------------
--------------------------------------------IL---IQASDVG----
-D--VHEGFKT----LKEEVQRETQEVDRLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELELEGALDKGREV---TLEALPKDV---------LLS--KEAMGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MDKKILPVQLK
LVES----TMEQNFLQ-----DKE--SVFPLRPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYASLSLFQLLTKAS-------
-----------------------------------------------

-------------------------------------------MGPGGPGGARAVPEDAL
GAPLRQAIVSLLGP---TPRGRV-LARRLPRQADARPR-----PAGRPRFTTSMVS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRSVVRELD-RNGELIPVNSLQNATGFRPYGLLSRKPS--SSWFWRPH-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPDLECSG--
--------------------------------------PFLFYDAMDGQ-LQGSVKLAVP
CQG-----RISGGAS---------VSDSSST----------SMDVC-ALHVDP-NIWEAM
H-KE------RRLRQPEHKVLQQLRSRG--NDVYVVTEVLQT----QKEVEVT---RTHK
QEGSGRFALPTAMCL------QG-EG---RG--HLSQKKVVTI-PSGTI-LAFR-VAQ-L
II--GSD-WDIHLFPDKKERT------FQPPSRGEAQGRP--TW--PFPWASQ-------
-----------------------GP--V----------APRQ-CQP---SVPT-DGLSEK
QVATED--FQG----LQAEVGAMSTELEHMEPGL-SRQLLGYLAAML--QNKPALQA---
LEDSLEQGLCC---GQAEPLDGPAGAVLECLLFPSGMLV--QELANSILYLLGAL-T---
-----------------------------VLSETQHVLL-AEA------LETGALPGQLK
LVGS----LLKQA--------PWQERGTVSLPPGLL----G-SSWH-E--GAPAWVLM--
-----EECGLDL--QVD-APHVRW---EPQAQGPTC-ALYASLVLLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPYSFDR
ICKDVVKKLQ-G-KDLCPVKCLSDATKFRQFAILQKTS---QSWHWTSED----------
-IPVGYSLLQILEPN----------------------------V---P--SPETEVSA--
--------------------------------------PMPFKRIVSKK-LKG--NVGVN
-AIAEG--SVSTGF-----------GHSYGY----------DIEVQ-CTSIPA-SKLGIL
Q--N------RKLVENEPSFVKDCWIGR--KDLYVVTEAYEV----TKATVLE---DSST
EDLSGQAPIK-----------------------SGGSKTDIPI-PKGAV-VAYR-KKQ-L
VI-ENDT-CGEQMWGPSGFGV---SNDLNLLFSPVCR-S---------------------
-----------------------------------GG----------------A

PF04598 // ENSGT00530000063218_Domain_1 (595, 790)

ILTAEE
-P--LHNDFLN----LEREIFEKTQMLPILSKDV-QDAVFSSLLPML--GDRDTLYD---
LMSMLEL----D---QLGHMDGPGGMILDELRK---DSW--NVLKDLLLYLLHAL-M---
-----------------------------VLSDTQLSLL-AQS------AEKRLLLHQRE
LVRN----LHGAGIQ------GWG--DES-----------------------RKWKNI--
-----LEESFH--------KERNQ---VTCAKMPMS-ALYGSLSFLQQLVEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAIAI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFGT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEVVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPL-DPTD--
------------------------------------CGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALENL
H-KE------RKLA-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWDIPHICNDSMQT------FPPGGRCGPGEGA--------------------
--------------------------------------------SA---ALTVPLG----
-E--MHEDFKT----LKEEVQRETREVEKLSPVG-QSSLLTSLSNLL--GKKKELQD---
LEQTLEGALDKGHEV---TLEALPKDV---------LLS--KDVTGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSILQLLSKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PHGDLTPLDSLIDFKSFRPFCVVLRKRK--STLFWGAR-Y---------
-LRTDYSLLGLLEPG----------------------------T------SPT-DPTD--
------------------------------------AGSFGFKNMLDAH-LEGEVDVPRT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-TALESL
H-KE------RKLA-ADHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MI-SGQDEWDIPHLYNDSMQT------FPAGEK-----PEEEK-----------------
----------------------F---------------------TL---IQASDVG----
-E--VHEDFKT----LKEEVQRETREVGRLSQVG-QGSLLSSLCNLL--GKKKELQD---
LEFELEGALDKGHEV---TLEALPKDV---------LLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-AKS------MEKKILPVQLK
LVES----TLEQNFLQ-----EKE--GVFPLRPELL----S-SLREEE--LTLTEALV--
-----GLSGLEV--QRS-SPQYMW---DPDTLPRLC-ALYAGLSLLQLLAGSP-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 857)

MFEK
EAKNVVKELG-T-KNLIPVTSFYSSNQFRPFCLMRKKRSHIFSHFWEKPL----------
-IPTDLSLMDILEPS----------------------------S---I--NPELTYTG--
--------------------------------------PFKFSFTVDGK-LKT--DMDFN
-AGVTI--GVSAEV-----------TRSHKS----------FLEVQ-IVNVPQ-VMWTNM
Q-RN------RKLLQPEHSFLLECWNRR--EDLFVVIEAVEV----LNSPVIQ---SSSN
IGGDGKLTLSRISNV------QD-KSG---A--HLNRQKSVSI-PKGSI-MAYR-AVK-L
LI-QEEK-WVILHIPDHEK------NTFQYKKRGTSS-SQTQ-----STWTQELA-----
-----SST--------------------------------MGLCYS---GLLLPSLPNLG
SY--SLTDFQR----LLEEVTFQKKDLVRMPGKQ-RTTLLCALHDLL--GNRTALQD---
LEDKLLHVLDSG---IWGKMEGPGNTILSNLQDSSDSPV--NGYITGFLYLLEAL-A---
-----------------------------ALSDNQHDLL-AQS------LEKKILSQQLK
LVKS----ILETNFNQ-----FHS--T--FILPPEI----L-SLIDEE--LNLSLELV--
-----EDCGLQL--QRT-EQMLIL---DPEGKNPLC-ALYGALSCLLSLSED--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-IRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------AGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFTPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHKGFGT----LKEEVQRETQEVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MRYSFNQ
ICKDVVKELE-G-KDLRPVKYLSEAKNFRQFEILQKTT---KSWHWKSEY----------
-IPVGYSLLEILEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PMPFRLSGSKK-LKG--GLGVN
-AIAEG--SVSAGI-----------GDSYEY----------DIEVQ-CTSIRA-SKLEIL
Q--N------RKLVEKEPTFMKDCRIRN--KDLYVVTEAYEV----TRDTVLE---DSSS
VDLSGQV---------------Q-VQG-E-W--QREKKRLVPI-LKGAV-VAFK-KKQ-L
VI-ENDT-CAILLCDDAKKK------TFPGMFP---------------------------
------------------------------------------------------------
-------GS

PF04598 // ENSGT00530000063218_Domain_1 (610, 836)

KH----LQNEISEKTWKLARLSKDV-QEVVFCSLLPML--RDREILYD---
LMIMLEM----G---ELGHMDGPGGVILDELRK---DPW--TGLHDLILYLLNAL-M---
-----------------------------VLSDTQLNLL-ALS------MEKRLLLQQRE
LVKS----ILQQNFKY-----PWN--IPFTLQPELL----A-PLQGEG--LAITYE----
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------MKEKG---QNYLPEMS

PF04598 // ENSGT00530000063218_Domain_1 (118, 863)

FHK
TTKSLAKKLN-PEGDLIPVRSIIDNDHYRPLCLLYRKAN--SSWWKTKS-F---------
-RKSEYKLTDVLCFG----------------------------D---H--AIKLDVK---
-----------------------------------DGGQFDIEDRVDGT-LQGEFSG-RD
-I---APIEAKTNS-----------IITHVM----------SVKVK-KIQLCP-TILNSV
KKVF------RKIN-MDHEFIKQSKKHD--YNLYIVTEAIEA----VEEAHFE---ESSE
MEGSIFYEAY--V------KMGL-KG-------SSKSKKAIHI-PKSCI-LAFR-AKK-L
QV-AKKS-RYDDRIPNNTVHSI----FRVA--P---------------------------
---------IAKKMK-----ESRLR---------------WFGHVQ-----QSDEGSV--
-----AKTALNIKENMWMEVQVECEQFSFLSAKL-RGLFLSGFVAVM--RNKDLLQK---
LAFQLEEALQVSGQCKLKADEPELQNLVENLQDCSGVII--TELAEAVVYFLEAL-D---
-----------------------------ELQEQQLMLL-EES------VGKNIVSMQLE
LVEN----ILGNILSN-----DK---MKFTADAQLL--------PKEE--MIITGAMI--
-----EMSGVTI--QKN-EAHLTG-TGEP---EALV-PLYVVLYVLNLLTQKTT------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRK-KD-SRSSIWGQSDY---------
-VPVGFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSD
VNISGKIS-LWITYG------KG-QGQ-GDS--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LVSCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---TLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNCAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDIQHDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-SPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 851)

AFEK
VVRSVVRELD-H-KELTPVDSLWSSASFQPYSLLSRKPL--HSRFWRPR-Y---------
-MCVNLSIRDILEPD----------------------------A---P--EPVLECGG--
--------------------------------------TFQFHDAMDGQ-LQGSVNLEAP
GQG-----RLSGGAT---------VSGSSSA----------SMDLC-TLRVAP-NTWEAM
H-HE------RRLRQPEPKTPQQLRRRG--HDVFVVTEVLQT----QKEVEVT---RTHK
QEGLGQFALLGALCL------QG-KG---EG--HLSRKKMVTI-PSGST-LAFR-VAQ-L
VI--GSD-WDILLFPDKKQRT------FPSLQKGHRPSSSADGH--PRPCFSFTSM----
--------------------------------------RGFSYSSC---QFQS-DGSMEH
WLATT-DDFQG----LQAEVKAWAVGLEGLSKGL-CGQLLGGLGQVL--RDEPALQA---
LEESLEQGLCGG--QM-EPRDGPVGAILESLVLPSGQLE--MELADSVFYLLQAL-A---
----------------------------------QHGCW-LVV------LETGALSGTFW
LVEC----LVEQS---S----PWQEHRAVS------------------------------
------RCGLEP--QVG-TPQVCW---EPGARGRVC-ALYACLALLFRLSRLC-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCVVLRKRK--GTLFWGAR-Y---------
-VRTDYTL-----------------------------------------------PTD--
------------------------------------AGSFGFKNMLDAR-LEGEVDVPRT
-------VKVKGAA-----------GLSWNS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLA-ADHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
LI-SGRDEWDIPHLSSDGSQT------FPAGEK-----PGEEK-----------------
----------------------F---------------------TL---IQASDVG----
-E--VHEDFTT----LKEEVQRETQEVGRLSQSG-QGSLLSSLSNLL--GKKKELQD---
LELELEGALEKGHEV---MLEVLPKDI---------LLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MEKKVLPVQLK
LVES----TLEQNFLQ-----DKE--GVFPLRPELL----S-ALGEEE--LTLTEALV--
-----GLSGLEV--QRF-GPQYTW---DPDTLPRLC-ALYASLSLLRLLAGSP-------
-----------------------------------------------

------------------------------------------------------------
--------------------------------------------------------

PF04598 // ENSGT00530000063218_Domain_1 (117, 859)

MFYK
VTKQLVKQLV-PDGDLLPVCNLIDQDHFRPLCLVRRKPK--KAFCRTLH-Y---------
-AKTGFRLWDILVPG----------------------------E---D--STHLDVQ---
-----------------------------------DSGPITVVDCVDGT-LKGSVKVPVD
-F---GRMEAMGAA-----------STYQVK----------SIKMK-KVHVSP-ANLELL
K-KE------RKIN-MNSSFIKQLRESR--ENLYVIYEAVQA----LEETTFF---KSNT
TEGSILNEIY--V------HFSL-KG-------TRGSKRAIII-PKDCV-LAYR-ILP-L
II-ADES-WDLSYHPGGK--------TFVADGA---------------------------
---------TEE--------YD---------------------YSY-----DGGID----
--------------DLKTEVENKCAELSQLSTDL-RAKFLKSIIAVI--IDSDLLQE---
LKFKLEEAFEDADKCELKSDNPDLEDLLNNLQDSAGSIN--LFLVDPVLYTLHAL-E---
-----------------------------ELTEDQLLRL-AQS------VEKKIVPKQLE
LVKS----ILKQEASS-----L---------DANII----S-SLQEEE--LNITKAMI--
-----EMDGVKL--QRN-GLYPIK-TGDMAAFAAFS-ALYVALYALHLLSRSE-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSY

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFDW
LSKDVVKKLQ-G-RDLRPVKCLSDATKFCLFNILQETS---SRLALKTE-Y---------
-IPVGFTLLHLLEPN----------------------------I---P--VPEPEVSA--
--------------------------------------PIPLKHTISQK-LKA--DLDVE
-----T--IAGGEAG---------FVKSCGY----------DIEVQ-SKSIPN-PKLESL
Q--N------RKLLDQLPTFMKTCWKDG--KNLYVVTEAYEV----TKDTVLE---GTSN
SKFAIKGIINQLVKV------GG-SG---QW--QTEKTDSIPI-QKGSV-LAYK-KQQ-L
VI-EDNT-CVILTSANTKK-----KMTFPMRFVGMSG-----HLR-YQDL----------
---------V--------------------------IET---GSWI---NDIDPIGTIKE
-P--THLDFMC----LQNEVSEQTRLLAELSKDV-QEVVFSSFLHMLCDR--DVLYD---
LMKMLEL----N---QLGHMDGPGGKILDELRKDSSLSW--INLKDLILYLLQAL-M---
-----------------------------VLSDTQLCLL-ALS------VEMRLLPHQVE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLSEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSV

PF04598 // ENSGT00530000063218_Domain_1 (118, 797)

FEE
FIRTVVQEMD-PGGDMIPVRSVIDADRFYCFCLVREKRS-----FLGSW-Y---------
-YRTDLTLMDILERR----------------------------EGEGP--CDELDSGLQ-
------------------------------GQYEA---EFQILDKVDSK-GKLI------
--------------------------GSHEQ----------KSKKL-KNQISQ-QYLDTL
E--N------RQLKKKLPPSFQSIHTKR--EDLYLVTETLET----AKEETLK-------
--SEGQCGFLSQIYQ---GHL---NY------QRNT-QGKSPS-PPNRV-LGYR-IKQ-L
VF-PNEE-KM--------------------------------------------------
-------SICFWGKT-----KSFPE---------------GEFLI------AASTG--K-
SL--SSEDSRN----MKEKVQDMVRSLQGLMEEE-RRDVLSCLTKCL--SKDEHLQD---
LEQRVRDPKTG------LGRSSP-----EQPFNTAGILV--EAHAEASLDFLDAL-I---
-----------------------------EVSE-EKQLV-AEA------LEKGTLPLLKD
QVES----ILEQVWDKQ-ASNAHD--MSCDPE----------------------------
-------------------------------TRTFC-ALYVAVSILLQLCSEPTSASS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MTS

PF04598 // ENSGT00530000063218_Domain_1 (117, 873)

MFER
HVKNLLKEVG-K-NDLQPIKNLSDAIKVHQFIIIRKKKGNFLSLLWKQPD----------
-IPTEFSLMDLLEPS----------------------------S---S--IPETVSTE--
--------------------------------------PCSFHFTGFKK-LKGGVDMEVN
-TGLEV--STSGEA-----------SKFQES----------SLQFQ-FVTVP--PNLEDL
Q--K------XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX-----XXXXXX---XXXX
XXXXXXXXXXXXXXX------XG-QVQ-GEG--LQMNKEMLTL-PKGLV-VAYK-RKQ-L
VL-KKM---AILHVSDDGE-----ENTFQDKLTPCVS-GCL-------------------
-----------------------------------------LXXXX---XXXXXXXRIEE
-P--ISRNFKL----LQKEISQKMEALASFPKDL-QYNVFHNILAML--GDRAALQH---
LMDMLEE----N---PSGHLDGPGGTILGGLQKNTEDLW--VGQGYHIRDILEAL-M---
-----------------------------VLSDTQHDLL-AQS------MKMRILAQQRD
LXXX----XXXXXXXX-----XXX--XXXXXXXXVL----S-SLESVD--EAHALSLV--
-----QSCGLEL--QVL---SSSS---DPEVTPQLS-ALYEALAWLQLLAWPW-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPHSFDW
VCKDVVKKLQ-G-KDLNPVKCLSDAMKFRQFEILQTDP---QSLFWKSED----------
-TPVGYSLLQILEPN----------------------------C---P--VPEPEVSA--
--------------------------------------PIPLKHTLSWK-LKA--NTGVN
AAIAEG--SVSAEF-----------GQSCGY----------DIEVR-CTSIPD-SKLESL
Q--N------RKLLDREPSFVKNCRMGR--KELYVVTEAFEV----TKDAVLE---DSSS
VDLSGKVGIPQVVKV------WD-RDV-KKT--SSERMDSVPI-LKGAV-VAYK-KKQ-L
VI-ENNT-CGEQTWEKL-------------------------------------------
--------------------------------------------------VLL

PF04598 // ENSGT00530000063218_Domain_1 (594, 864)

FLGRIEE
-P--FHLDFKR----LQDEVSRKTWELSMLPEDD-QNVLFSSLLPML--SDRKILYD---
LINMLEL----D---QLGHMDGPGGMILDVLQQ---NPW--IDLKKLILYLLQAL-M---
-----------------------------VLSDNQLSLL-AQS------MEKRLLLQQQE
LLHP----FL---------------------------------FTGEG--LVITYELL--
-----KECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSLLQ----PGPSSVHVE
SWRH-------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MTS

PF04598 // ENSGT00530000063218_Domain_1 (117, 530)

TFER
VVKSVVRELD-PKGDLIPVDSLRSSISFRPYCLLGRKLS--SSWFWKPR-Y---------
-KCLNLSIRDILEPD----------------------------A---P--EPAVERVA--
--------------------------------------SFHIEDLVDGM-VEGNVEVKAL
GQG-----KFVSGAA---------VSATAST----------SVNVC-MLKVPL-NTWGAM
K-KE------RRLRQPEHKILQQLRSCG--NDVFVVTEVLQT----QEEVEVT---RAQK
QEGCGQFALPGALRL------QG-KG---QG--HLNRKKTVTI-PSGSV-LAFQ-TAL-L
VI--GPD-WEIHHLRHKDERT------FRLPQTGHKPTSSTGLL--SQIPLSFFKMRFPS
TPVDMVSGQYLLDDPQTLGGLPFAPWESALPDQGSPGSCGRPGNSS---PLHT-DGDIED
QMPV-TEDFQG----LKVEVSVHADGLKGLSGEL-CGQILAGLMKVL--REEPALES---
LQEEVSSLLEWA--GWVGPAPGPSGSPAPPYVPSWNRACAVGGWRPPMPRGVPSW-S---
------------------------------------------------------------
---------------------AWCSPLER-------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPST

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEC
AVKNIVKELS-KNGELIPVESLKSSSHFSPYYLVRKKTKS--FWFWSPQ-Y---------
-VWLNLTLKDILDPS----------------------------S---P--EPEVIQN---
-------------------------------------GPFHFNDEVDGK-VSGSVE--VT
-ASVQG--RISGQT-----------S--NRT----------DLEVK-TLMVPL-HTWDCL
Q-KE------RTLKKPEPSILQELRKRN--EDIYVVTEAVKT----QKEAVLK---RSRN
TEGFGKFTI-----PGAS-CFQG-QG---EG--HLKAVKTVTV-PEGSI-LAFQ-VAK-L
II-R-NH-WNVLLFPDKKQ------KTFPEESIRFTS-----------------------
--------------------------------------------HI---E----SDVST-
VN--IATEFEK----MQAEVKEERNLLTMLDKKL-RQCLLQDLLRLL--QSKEDLLD---
LEGMLEESLFSG--VPLQKTEGAMGNILSNLQDRSGKLV--EELAGAFLYLLGAL-S---
-----------------------------ALSEIQYQIL-IQLLK----TEEKILPQEID
LVRE----ILRKNFNQ-----TKE--TTFFLPSELL----S-FAKDKREESILICVLL--
-----KECGLEI--SGD-KSQFTW---NPNALHSLC-ALYGSLEMLQALSKGC-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 514)

AFER
VVRRVVQELD-HGGELIPVTSLQSSTGFQPYCLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPDLQRGR--
--------------------------------------SFHFYDAMDGQ-LQGSVELAAP
GQA-----KIAGGAA---------VSDSSST----------SMNVY-SLSVDP-NTWQTL
L-HD------RHLRQPEHKILQQLRSRG--DNVYVVTEVLQT----QKDVEVT---RTHK
REGSGQFSLLGTMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDVLLFPDKKQRT------FQPPPTGESREPP--AW--GVRWEKH-------
-----------------------TPWAV----------EAFSSCSQ---GTGR-PGSPPE
AVGTPHTHTKG----DTGQLNPG----PPWPPLL-CP----GI-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLIPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-IHTDYTLLDVLEPG----------------------------S------SPT-EPTD--
------------------------------------SGNFGFKNMLDAR-VEGKVDVPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KVLESL
Q-EE------RRLA-EEHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SLNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-RGKDGWDIPHMCNDDMQT------FSPGGQPEKKFLR--------------------
---------------------------------------------------TFVIG----
-E--AHEDFKA----LQEEVQRETQEVKKLSQVG-QSALLSSISKLL--GKKKELQD---
LETNLEGALDKGHEV---TLEALPKDV---------LLS--KEVMGAVLYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKVLPVQLK
LVES----TLEQNFLQ-----DKE--GVYPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPHLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFYPFCLVLRKRK--STLFWGAR-Y---------
-VHTDYSLLDVLQPG----------------------------N------SPS-DPTD--
------------------------------------SVNFGFKNMLDAR-VEGEVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALEDL
H-KE------RKLA-ADHPFLKEMRERD--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SMNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-HGKDEWDIPHIYNDSMQT------FPPGEPRWESD----R-----------------
----------------------L---------------------LA---TSTVPLG----
-E--AHEDFQT----LKEEVQRETHEVEKLSRVG-QSSLLSSLSKLL--GKKKELED---
LELTLEGALDKGHDV---TLEALPKDV---------LLS--KEAMGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MEKKILQVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

--------------------------------------SGRASWAGPASGCSFTFSSGHL
--------------------QLL-LAGRLPGRADAPDAPPSG-----RRRSRSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRRVVQELD-HGGEFIPVTSLQSSTGFQPYCLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------T---P--EPDVQRGR--
--------------------------------------SFHFYDAMDGQ-IQGSVELAAP
GQA-----KIAGGAA---------VSDSSST----------SMNVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKVLQQLRSRG--DNVYVVTEVLQT----QKEVEVT---RTHK
REGSGRFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--DSD-LDVLLFPDKKQRT------FQPPPTGHKRSTSEGAW--PQLP----------
--------------------------SG----------LSMMRCLH---NFLT-DGVPAE
GAFTED--FQG----LRVEVETISKELERLDREL-CQLLLKGLEGVL--RDQLALRA---
LEEALEQGQSL---GPVEPLDGPAGAVLECLVFSSGVLV--LELAIPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTMSLPPGLL----G-SSWG-E--GAPAWVLL--
-----DECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

MGYS

PF04598 // ENSGT00530000063218_Domain_0 (5, 114)

FDRASKDVVKKLQGRYLRPVECLSDATKFRLFHILQETPRSGWETEDIPV------
----GFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLESNLNVADIAGGGVGNMGYSFDR
ASKDVVKKLQ-G-RYLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PKPFIHVQSTD-LES--NLNVA
-----D--IAGGGVG---------YVGYGGY----------NIEVQ-SKSIPS-PKLENL
Q--N------RKLLDKLPTFMKICRMER--KNLYVFLF----------------------
------------------------------------------------------------
------C-PV

PF04598 // ENSGT00530000063218_Domain_1 (491, 864)

ILPSAT-KK-----KMTFPGTPKYASA-S-EPTET-SRT-----------
---------------------------------------QLEGLWI---NDIEPIGRIQE
-P--AHLDFKC----LQYEVSEQTRLLPELSKDV-QEVVLSSFLSMLYEGDRNVLHD---
LMKMLEL----N---QLGHMDGPGGKILDELRKDSSNPC--VDLKDPILYLLQAL-M---
-----------------------------VLSDSQLNLL-ARS------VEMGILPHQVE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLRKANSSSKPSL
RPGYI------------------------------------------

------------------------------------------NLRLLGSGNSPA------
---------------------------------S-----RADAPPPGRPRSRNMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VARRVVQELD-HGGDLIPVTSLQSSTGFKPYCLVVRKPS--GSWFWKPR-Y---------
-KHISLSIKDILEPD----------------------------A---P--EPVLQHGG--
--------------------------------------PFHIHDTVDGQ-LRTSVEVAVP
GQG-----KVAGGAS---------VSDSSST----------SLNVF-SLSVGP-NTWQAL
L-QE------RHLRQPEHRILQQLRCRG--DNVYVVTEVLQT----QKEVEVT---RTYR
REGSGLVSLAGAMCL------QG-EG---EG--HLSQKKTVTI-PSGSI-LAFR-VAL-L
VI--QSD-LEVILFPDKKQKT------FQPPPTGETW-----------------------
---------------------------G----------VQWENSQP---SVPT-DGVPVN
GTVTED--FQG----LRAEVEVVSKELALMDGQL-CRLLLEGLERGL--RDQLALQA---
LEEALEQGLSS---GPVEPLDGPAGAVLDCLVLPSRMLV--LELAVPVVYLLGAL-N---
-----------------------------TLSKAQHQLL-VEA------VELKTLSRQLE
LVGS----LLEKS---A----PWQKCSTLSLPPELL----K-SGWG-V--ETPAWVLL--
-----EECGLEL--RED-PPHVHW---EPQAQDCVC-ALYASLALLSELSQEPQ------
-----------------------------------------------

------------------------------------------------------------
--------------------------------------------------------

PF04598 // ENSGT00530000063218_Domain_1 (117, 496)

MFKN
VTKFIVNQMD-PCKELVPVESIADNEHFRPLYLLKRKRKPKTIFHPAPY-Y---------
-QRTGFTLHDVLLPG----------------------------E---D--GKSIESLHQ-
------------------------------D-----SCQITITKASKDQ-ADGGLSISCD
-P---ASVDLQGGG-----------SLSKEF----------SITPQ-KKSISL-QSLEAL
R-RE------REIN-MDHSFIQQLRRTD--INLYVVTEILEA----SEETVYK---ESTK
ADGGFKAKFY--A------TLCAKQG-------TREDKQTIVI-PKGCT-LAFR-TIP-L
HI-RDGA-WDLDYFPVEALRRA----AYIADGP---------------------------
---------------------------------------------S-----QGKLG----
--------------VVASEVKYSCRNFPDLSPDV-LLIVFNTIKAVM--RDKNLLQE---
LTQKMEDIPEQNDGYELKTESPHLKDLFSTLQHSPRDCL--LQVAGGITYVLDALHA---
-----------------------------ELMDDQLLLL-LES------LERKILSQQLK
LVEN----LLKHDLDK-----GK---S-FHVDARLL----SFPH-EEE--LMLTMELV--
-----ELSGVQL--QED-GSAVPR----DQPFESVA-ALFVAMYALNLLSGSKGACSKGQ
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEK
VVRSVVRELD-H-KDLTPVDSLWSSTSFQPYTLLSRKPL--SSRFWRPR-Y---------
-KCVNLSIRDILEPD----------------------------A---P--EPALECGR--
--------------------------------------TFQFHDAMDGQ-LQGSVKLAAP
GQG-----RLSGGAA---------VSGSSSA----------SMDLC-TLRVTP-NTWEAM
H-HE------RRLRQPEPKTLQQLRSRG--DDVFVVTEVLQT----QKEVEVT---RTHK
QEGSGQFALPGAFCL------QG-KG---EG--HLSQKKTVTI-PSGST-LAFR-AAQ-L
VI--GSD-WDILLFPDKKQRT------FLSLQAGRRPSSSADSH--PHPCFSLASI----
--------------------------------------RALSD-YF---HFQP-DGSTEH
WLATT-DDYQG----LRAEVKAWAMGLEGLSKGL-CGQLLGGLGQVL--RDEPALQA---
LEDSLEQGLCSG--PV-EPRDGPVGAILESLVLPSGQLE--TELAGPVFYLLQAL-A---
-----------------------------VLSEAQHVLL-AEV------LEMGALSGTFW
LVES----LVEQS---S----PWQEHRAVSLPPERL----G-DSWG-S--EAPGWALL--
-----EACGLEP--QVG-TPQVCW---EPGARGCAC-ALYACLALLLRLSQLC-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MCAW-----------K----------------------
------------------------------------------------------------
------R-G

PF04598 // ENSGT00530000063218_Domain_1 (490, 827)

FILPSAT-KK-----KMTFPGTPKYASA-S-EPTET-SRT-----------
---------------------------------------QLEGLWI---NDIEPIGRIQE
-P--AHLDFKC----LQYEVSEQTRLLPELSKDV-QEVVLSSFLSMLYEGDRNVLHD---
LMKMLEL----N---QLGHMDGPGGKILDELRKDSSNPC--VDLKDPILYLLQAL-M---
-----------------------------VLSDSQLNLL-ARS------VEMGILPHQVE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQATS--EG--------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------D-

PF04598 // ENSGT00530000063218_Domain_1 (445, 864)

EGV-GED--RIVKETKLTL-PQGMV-MAYK-MKP-L
VF-KEKD-IL--HIADEKQ------KCFP----EL-------------------------
------------------GW-----------------------------EMQPLPRRAQG
-S--CWLDFRH----LQAEVSHYVKK-AQLLEKV-GNVVFSSILAML--GDREALHD---
LEDKLEQ----K---PLGHLDGLGGAILNALREGSYYKS--VNSEDPIPYLLGVI-I---
-----------------------------MLSDLQHDVL-AWS------VKKKILLQQRD
LVRS----ILEPNFKY-----LMD--IPFTIKPEFL----A-PLQGED--LDITYRLL--
-----KECGLRM--EPN-SPRSIW---VLNAKTPLS-ALYAALTVLQQLAEA--------
-----------------------------------------------

MGYS

PF04598 // ENSGT00530000063218_Domain_0 (5, 114)

FDRASKDVVKKLQGRYLRPVECLSDATKFRLFHILQETPRSGWETEDIPV------
----GFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLESNLNVADIAGGGVGNMGYSFDR
ASKDVVKKLQ-G-RYLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PKPFIHVQSTD-LES--NLNVA
-----D--IAGGGVG---------YVGYGGY----------NIEVQ-SKSIPS-PKLENL
Q--N------RKLLDKLPTFMKICRMER--KNLYVFLF----------------------
------------------------------------------------------------
------C-PV

PF04598 // ENSGT00530000063218_Domain_1 (491, 864)

ILPSAT-KK-----KMTFPGTPKYASA-S-EPTET-SRT-----------
---------------------------------------QLEGLWI---NDIEPIGRIQE
-P--AHLDFKC----LQYEVSEQTRLLPELSKDV-QEVVLSSFLSMLYEGDRNVLHD---
LMKMLEL----N---QLGHMDGPGGKILDELRKDSSNPC--VDLKDPILYLLQAL-M---
-----------------------------VLSDSQLNLL-ARS------VEMGILPHQVE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLRKANSSSKPSL
RPGYI------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGSAFER
VVRRVVQELD-HSRELIPMTSPQNSTGFQPYFLVVRKPS--SSRFWKPH-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPGSPS-P--
--------------------------------------PFPMGSRSRGE-P--TERLPVP
RHP-----QTSGGPL---------CTTSPS-------------------------A-YGS
S-DH------RHLRQPEHKILQELRSRG--DNVYVVTEVLQT----QKEVEIT---RTHK
REGSGRFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGENGETP--AW--GVPWRKH-------
-----------------------ASLAI----------EAFFSCSQ---GIGR-LG----
------------------------------------------------------------
---------------------SPRGGAQ---VSPSD------------------------
------------------------------------------------------------
-KLL----

PF04598 // ENSGT00530000063218_Domain_1 (789, 864)

LLEQS---A----PWQERSTMSLPPGLL----G-SGWG-E--GAPAWVLL--
-----EECGLEL--GED-TPYVSW---EPQAQGRMC-ALYASLALLSGLSPEPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-TALENL
H-KE------RKLS-ADHPFLKEMRERG--ENLYVVMEVVET----LQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAYR-VRQ-L
MV-NGKDEWGIPHICNDSMQT------FPPGEKPGEGKFI--------------------
--------------------------------------------L----IQASDVG----
-E--MHEDFKT----LKEEVQRETQEVEKLSPVG-RSSLLTSLSHLL--GKKKELQD---
LEQTLEGALDKGHEV---TLEALPKDV---------LLS--KDAMDAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKKILPVQLK
LVES----TMEKNFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPHLC-ALYAGLSLLQLLSKNS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
DAKKVVKELG-K-RDLIPVQSLLTSPRFHPFCLIRKKEKK-FPWFFEPT-F---------
-LDTYFSLMDILEPS----------------------------S---S--VPEVTSS---
-------------------------------------KPLHFYETEYTE-LQGNMDLNVT
-REVQG--KVTGAT-----------TSSHNL----------ALKLQ-ILTVVP-QIWETL
--ME------RKVK-SKHSFLQEVQNRG--EKLYVVAEAVEI----IEDTILM---QSNK
NEGSIQASLGQLSSLPGI-NFKG-EG---KG--QTDGKKGVSV-NQGYI-VAFR-ALE-L
FI-HNDK-WKLPNHQQRLLNQSTKEPSFTSVCVAQDSDLNYRYIR----LHDSVPYNSLG
DFFSLFLVEEFYIGE-----LGIPK---------------VYFYSS---IFTDRLTGKH-
IY--APTNFEE----FQEMMIREQEALLKGSREL-RVTLLHVIQNIL--GNRKALHD---
LEDM---VPD-M--REKGQLEGPGVCILKHLQDNSGDAS--NQQTESILYFLGAL-M---
-----------------------------ILTDTQQELL-AQS------LEKRILPQQLE
LVKS----ILKTNFGQ-----PGE--SSFSVHPKLL----S-ELKDED--QAITMNLM--
-----KECGLNL--ECA-GSQTKW---NREAESSIS-ALCVVISFLQLLTQA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q-QE------RKLA-ADHPFLKEVRDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFSPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGGKPGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFRT----LKEEVQRETQQVEKLSQVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEAIPRDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVEC----TMEQNFLQ-----DKD--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLSKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 410)

IFKE
TTKAVLQEMN-PRGDMIAVQNPVDADRFYCLCLVRKEKS-----IWGHQ-Y---------
-CSTDITLQDILEEE----------------------------ESKEL--SDERDSVFR-
------------------------------GE-KT---EFRIEDTVDTK-GEATMKVFEE
-VTITG------SF-----------QGSHEL----------KLKLL-SKRLST-QYLNTL
Q--N------KKLKKDLPASFQSFPK-E--KNLYLVTETLET----EKETLDS-------
--NS-VYT--LWDKVXXXXXXXX-XX------XXXX-XX--------XX-XXXX-XXX-X
XX-XXXX-XXXXXX----------------------------------------------
---XXXXXINFWSKT-----KSFPE-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
MS

PF04598 // ENSGT00530000063218_Domain_1 (123, 864)

LNLVKELG-D-KDFRPIQNPLSANKFCQLKLLRKKR-RTLSQFWERPD----------
-VPVDCTLTDILEPS----------------------------P---S--VPVPVVTE--
--------------------------------------KFVFIDKMVWK-GAA--EVDVT
-AGLEV--CVSGKA-----------NQSYEC----------SLEVQ-SVTISP-CNWEDL
Q--K------RKVLDQEPSFLKECRTRG--DNLYVVTEAVKL----INRTVLQ---DSSR
VNVTGQFSVPWSFYA------KS-TGD-RSG--LKVRERTLTL-PQGTV-MAYK-RKQ-L
VF-RENG-RGKQDR------------TP--PPGITWA-LLTCLLP-HPEI------LSIS
--ED-GKQKAFSE-------------------------------DD---EFLSGAGSLPS
PQ--ALTDFKS----LQNEVSREMEAVAELPRDI-RDALFHTILAKL--KEQGALQD---
LTDMLDG-----------NLWIHTGSFLSEMQEDSRNVW--LESK-HIIYLLEAL-L---
-----------------------------VLSDIQHELL-AWS------MEKRILPQQRE
LVKS----ILEPNFRY-----LWN--IPFTLDPKLL----A-LLQEEG------------
------ECGLRV--APN-NPKGTW---DLEAKKPLS-ALYGSLSVLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEK
VVKNVIKEVSGSRGDLIPVDSLRNSTSFRPYCLLNRKFS--SSRFWKPR-Y---------
-SCVNLSIKDILEPS----------------------------A---P--EPEPECFG--
--------------------------------------SFKVSDVVDGN-IQGRVMLSGM
GEG-----KISGGAA---------VSDSSSA----------SMNVC-ILRVTQ-KTWETM
Q-HE------RHLQQPENKILQQLRSRG--DDLFVVTEVLQT----KEEVQIT---EVHS
QEGSGQFTLPGALCL------KG-EG---KG--HQSRKKMVTI-PAGSI-LAFR-VAQ-L
LI--GSK-WDILLVSDEKQRT------FE-PSSGDRKAVGQRHH--GLNVLA--------
--------------------------AL----------CSI-GKQL---SLLS-DGIDEE
ELIE-AADFQG----LYAEVKACSSELESLEMEL-RQQILVNIGKIL--QDQPSMEA---
LEASLGQGLCSG--GQVEPLDGPAGCILECLVLDSGELV--PELAAPIFYLLGAL-A---
-----------------------------VLSETQQQLL-AKA------LETTVLSKQLE
LVKH----VLEQS---T----PWQEQSSVSLPTVLL----G-DCWD-E--KNPTWVLL--
-----EECGLRL--QVE-SPQVHW---EPTSLIPTS-ALYASLFLLSSLGQKPC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPYSFDW
VCKDVVKKLQ-G-KDLCPVTRLSDAMKFRQFAILQRTP---QSLFWKSED----------
-TPVGYSLLQILEPN----------------------------L---P--VPEPEVSA--
--------------------------------------PIPLKHTVSQK-LKA--NTGVN
-AIAEG--SVSAAY-----------AKSCGY----------EIEVQ-CTSIPD-SNLESL
Q--N------RKLLDKEPSFVKDCRMGR--KDLYVVTEAFEV----TKDTVLE---GSSS
VDLSGKALIPQVAKA------Q--AQG-Q-W--QRETTDSVPI-QKGAV-VAYK-KKQ-L
VI-ENDT-CV--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------

PF04598 // ENSGT00530000063218_Domain_1 (750, 826)

-LSDTQLKLL-AQS------MEKRLLLHQLE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQG--------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MTA

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PQGDLTPLDSLIDFKRFRPLCLVLRKRK--GTLFWGAR-Y---------
-LPTDYALLDLLEPG----------------------------A------APT-ESTD--
------------------------------------NPHFRFKKLLDLR-LEGKVDVPNT
-------VKVTGGA-----------GLTQSS----------HLEVQ-TLSVAP-KALDTL
R-DE------RKLL-PEHPFLQELRPRG--ENLYVVMETVET----VKEVTLE---RAGQ
AQ--GGFSIPLLAPLGLQTFS--------QG--SLNHQEAVTI-PQDCV-LAFR-VRQ-L
VT-KGNGEWDIPHVCDEKLKT------FPPEAPSPSRPSDPHGP----SRLPSPKAAPPH
-----------------LPFSPFSL-----------------WKEM---SIKAWRA----
-E--VPEDFGA----LQEEVESEARQLAQLTPEA-RATLLRSLRALL--GKNHQLRL---
LEGSLEGALHKGTPG---ALEDLG-NV---------TLS--PQAMGSILYFLGAL-T---
-----------------------------ELSEAQQKLL-AQS------MEKKILLTQLK
LVER----AMEENFQQ-----SQG--GDFPLPPQLL----S-SLGDED--LTLTEALV--
-----GLSGLEL--HRA-GPRYTW---EPATLPRLC-ALYAGLSALHLLAAPA-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEG
VVRSVVRELD-QSRELIPVDSLRTSTSYQ------RKPS--SSWFWRPR-Y---------
-TCVNLSIKDILEPD----------------------------A---P--EPAVERVG--
--------------------------------------PFHFHDTMDGQ-LQGSVELAAP
GQG-----KLAGGAM---------VSGSSSA----------SMNVC-TLRVAP-NTWVAL
L-QE------RRLRQPEHKVLQQLRRRG--DDVFVVTEVLQT----QTEMEVT---RTHK
QEGSGQFALPGAICL------QG-KG---QG--HLSRKKTVTI-PSGSI-LAFR-VAQ-L
VI--DPD-WDILLIPNKKQRT------FAPPQAGSTRE------------SSSFSV----
--------------------------------------MKDLYDRL---KFLS-DGPTEN
CPVPT-EDFQG----LQAEVKAWASALENGSATL-CGQLLGGLGQVL--RDEPALQA---
LEESLEQGLCSG--RA-EPLHGPAGAVLECLVLHCRTPV--EELARPVFYLLEAL-A---
-----------------------------ALSETQHMLL-AEV------LETGALPESVE
LVET----LLEQS---T----PWQEREAISLSPRLL----G-SNWG-S--EAPAWVLL--
-----EECGLKL--QVG-APQVCW---EPEAQGPTC-ALYACLALLLKLSQLR-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 427)

FDR
ICKDVVKKLQ-G-KDLYSVKSLSEAMKFHQFEILL-TS---WSWPWNTED----------
-IPVGYSLLQILEPK----------------------------F---P--IPGIVSQG--
--------------------------------------AKNWKHQ------HF--HAGVH
-AIAEG--SVSAGH-----------GHSSGY----------SIEVQ-CTSIPA-SQLDIL
Q--N------RKLVEKEPPFMTHCRIKN--KNLYVVTEAYVV----TRDTELG---DSST
EDLSGQCVCDGVVME--------------IW--AILL--CPPI-PG--------------
----SGS-CGRG------------------------------------------------
---------------------------------------KVMEDWM---GQE--------
--------------------------------E------------------KQERIS---
NVCVFFS----R---KLGHMDGPGGVILYELRK---DSQ--DILKDLILYLLQAL-M---
-----------------------------VLSDIQLSLL-AQS------VEKRLLLHQRE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYGLL--
-----SECGLQM--ELK-NPRPTW---DLEAKMPMS-ALYGSLSFLQQFVEAKSFSEPGP
SPARCI-----------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSI

PF04598 // ENSGT00530000063218_Domain_1 (118, 487)

FER
VSKKMVKNFG-G-KDLRPVKSLLDATHFRQFSILRKN---PQSQFWEQPD----------
-IPVECSLMDILAPG----------------------------S---S--VPEVEVTR--
--------------------------------------PFFFSDTVIQK-WKA--GMSAS
-AGVDG--GASGEF-----------TQSRGS----------TLEFQ-KVTVPS-RNLERL
Q--N------SKLLDPEPSFLKHCRERG--DNLYVVTEVVEL----TNSTTLH---DKSS
VTTLGKLSGSWNILI------KV-WHG-------DTKTMTLTI-PQGTV-MAYK-KKQ-L
VI-KGNG-VSEYK-----------------------------------------------
-----------------------------------PG-------------RYLGWGR---
-V--ALADFKH----LQEEVFRKIEALAQLSKGV-QDDVFNNILPML--GDRGALQD---
LMDVLSW----G---QVGHM-GPGSIILNKLRQDSSPPW--VKPQDSILYLLQAM-M---
-----------------------------VLSDTQLELL-ALS------MEKRILLWQRE
LVRV----ILEPNFKY-----PWS--IPFTLPPELL----A-PLQGEG--LAITYGLL--
-----EECGLKM--ELS-SPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFKS
VVRSVLRELD-SGGQLTAVDSLHSSTSFRPYCLLGRKPS--CSLFWKSR-Y---------
-LCIDLSIKDILEPE----------------------------A---P--EPGAECSA--
--------------------------------------CFDFDDVVDAQ-VQGSVELAGP
GQG-----RIAGEAA---------VSGSSSS----------SMKVC-RLRVGT-STLEAM
V-RG------RRLRQPEPKILQQLRRRG--DNVYVVTEALQT----QQEVQVT---QARK
QEGSGQFTLSGAVHL------QG-KG---QG--HLSRKKMVTI-PAGSV-LAFG-VAQ-L
VI--GSD-WDILLLPEKKWKT------FQPLPPGDKPRSSSYSL----------------
------------------------------------------VPHS---GFEA-DAPAEW
PVLTE--DFQG----LRAEVEAKLLELECWDRRL-SRKLLGGLAPLL--RDHQALGA---
LESLLEQGLGR---EEPQPQDGPARAVFECLPRASGALV--MEVANPIFYLVGAL-T---
-----------------------------VLSGTQQELL-ARA------LETGALVGQLE
LVGS----FLEQS---V----PWEERSTVPLPPTLL----G-SSWG-E--DAAAWTLL--
-----EECGHEP--QAG-APEVCW---EPQAQGPTC-ALYASLALLARLSQ---------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSV

PF04598 // ENSGT00530000063218_Domain_1 (118, 582)

FEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFRCFHLVGEKRT-----FFGCR-H---------
-YTTGLTLMDILDT-----------------------------DGDKW--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDST-GELIVRLPKE
-ITI------SGSF-----------QGFHHQ----------KIKIS-ENRISQ-QYLATL
E--N------RKLKRELPFSFRSINTRE--N-LYLVTETLET----VKEETLK-------
--SDRQYKFWSQISQ---GHL---SY------KHKG-QREVTI-PPNRV-LSYR-VKQ-L
VF-PNKE-T---------------------------------------------------
------MNIHFRGKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--GSEDSRN----MKEKLEDMESVLKDLTEEK-RKDVLNSLAKCL--GKEEIRQD---
LEQRVSEVLISR----ELHMEDPDKPLLSSLFNAAGVLV--EVRAKAILDFLDAL-L---
-----------------------------ELSE-EQQFV-AEA------LEKGTLPLLKD
QVKS----VMEQNWDEL-ASSPPD--MDCDPE----------------------------
-------------------------------ARILC-ALYVVVSVLLELAEGPTSVSS--
-----------------------------------------------

------------------------------------VISAHCNLRLPGSGDSPASFHFWF
--------------------WAP-PAPPLPTAPR-----RADAPPPGRPRSRNMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
LVRRVIQELD-HGGDLIPVTSLQSSTGFKPYCLLVRKPA--SSWFWKPR-Y---------
-KHVNLSIKDILEPD----------------------------A---P--EPVLQHGG--
--------------------------------------PFHIRDTVDGQ-LRTSMEVAAT
GQG-----KVAGRVL---------VSDSSST----------SLNVF-SLSVGP-NTWQAL
L-QE------RRLRQPEHGILQQLRHRG--DNVYVVTEVLQT----QKDVEVT---RTRR
REGSGLISLAGAMCL------QG-TG---QG--HLSQKKTVTI-PSGSV-LAFR-VAL-L
VI--HSN-LEVILFPDKKQKT------FQPPPTGDSRE-----P--P-------------
--------------------------TD----------ISMKGCIS---NFWT-DAVPAN
GTVTED--FQG----LRTEVEAVSKELALMDGQL-CQLLLEGLEGVL--RDQLALQA---
LEEALEQGLSS---EPVEPLGGPAGAVLECLVSPSRMLV--LELAVPFVYLLGAL-N---
-----------------------------TLSKVQHQLL-VEA------MELKTLSRQLD
LVGS----LLEKS---A----PWQKRSTVSLPPELL----K-SGWG-G--ETPAWVLL--
-----EECGLEL--RED-PPHVHW---EPQAQGHAC-ALYASLTLLSDLSREPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VCTDYTFLDILEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLM-AEHPFLEEMRRRG--ENLYVVMEVVEA----VQEVTLE---RAGR
AE--GCFSLPFFASLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHIYNDNMHT------FPPGEKPEDEKFT--------------------
---------------------------------------------L---IQASDVG----
-A--VHEDFRT----LKEEVQRETQEVEKLSPEG-KSSLLSSLSKLL--GKKKELQD---
LELTLEEALGKGHEE---TLEALPKNV---------LLS--KGAMDAILYFLGAL-A---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSY

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFQC
ISKSFAKEFG-R-NDLTPVECRYHAIKLRQFAVLQKTE-RPFLVFWKKCDY---------
-APLNFSLSDILESS----------------------------P---S--VPDNDGNG--
--------------------------------------PLHFCDTMIQK-HEA--AIDVN
-VGEKL--RVSAGH-----------SADQKV----------SLKFQ-IVTISA-PNLEVF
Q--K------RKLLHPEPEYLKRCWKSR--DNLYVVTDIVEL----TSDTVLY---DYSS
MDLTGKIS-SWITGV------KV-YICPEVG--LKYKKKVLTL-KKGMV-MAYK-AKR-L
IF-EEKD-RTVR-VTDDDE-----RSICQYVYSVSER-LGYSVAM-NEEWLQSFTTISPT
LFNA-LSN-DI---KLKLGTGIA-------------QL--IF-GS----VMVLFFVQIVV
-K--IW-YFKC----LQGEVSRNIEALAQLSRDV-QGVVFSSILAML--RDRQNLQD---
LMYMLEL----D---SSGHLDGPGGAILKILQQDSNHAL--SKSKEPILNLLEAI-M---
-----------------------------VLSDIQHDLL-AYS------MEKRILLQQQE
MVRS----ILEPNFRY-----SGS--NPFTLKPELL----A-PLQRED--LAITYGLL--
-----EGCGLRM--ELD-SPKSTW---VGALKIPLS-ALYETLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFED
VVRRVIWELD-RSGKLIPVDSLQNSSSFRPYSLLRRKPP--SSWFWKPR-Y---------
-SSVNLSIKDILEPD----------------------------V---P--VPDLECGS--
--------------------------------------TIHICDNTDGK-VQGKVEVAVP
GQG-----KIAGGAA---------VSGSSST----------SMNLC-TLSVNP-NTWDHM
Q-QE------RRLRQPEHKILQELRSRR--DDVYVVKEVVQI----QQEVVVS---CTRK
LEGSGQCALPAAMCL------KG-DG---EG--HFSQENTVTI-PAGSI-IAFR-VAQ-L
VI--DTD-WSIFHFPDKKQRT------FPPPSTGSQPQHT----------FSL-------
-----------------------S--SV----------LGLIHERF---RLLT-DSVSEK
WEITED--FQG----LRTEVEAGSAELQKMERDL-RQQLLLNLEKIL--CDPSALED---
LEALLAQGLCGA--RQVKPLHGPADDILECLVLPSRMLV--PELAAPVFYLLGAL-S---
-----------------------------ALSETQQQLL-AKL------LDKGDLSTQLE
LVDH----LLEQS---T----PWQKQSDVSLPPRLS----E-SNWG-E--EAPSWTLL--
-----EECGLEL--QVG-APQIHW---EPQAQGPTC-ALYASLALLSGLSRESC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFQR
ISKSLVKEVG-R-DDLTPVKCLARAIKLRQFALLQKMN-TSRSVFWEQCDY---------
-VPLQFSLSDILESS----------------------------S---S--VPDNDVNG--
--------------------------------------PLYFYDTMIQK-YEA--GIGVN
-VGGEL--SVSGEA-----------SADQGG----------SLGYQ-IVTISA-PNLEVF
Q--K------RKLLHPEPEYLKGCRRRG--GNLYVVTDAVEL----ISDTVLC---GNSS
MNLFGKAS-LWITCG------KG-QGQ-GKI--FRKKEKGLTL-KKGMV-VAYK-TKK-L
IF-EEKD-RTIL-ITDDDE-----RSTFQDVYRISER-LGYSVAM-NEEWLRSFTTISPT
LLKA-SSN-DI---KLKLGTQIW-------------WG--MRKGDA---DLILIPGRIEE
-P--FWQNFKH----LQEEVSQNIEALAQLSKDV-QGVVFYSILAML--RDGEDLQD---
LMYMLKL----D---SSGHLAGPGSSILKILQRDSEHAL--SKSKEAILYLFEAI-M---
-----------------------------VLTVIQHDLL-AYS------MEKRILLQQQE
LVRS----ILEPNFRY-----PWN--IPFTLKPELL----A-PLQSED--LAITYGLL--
-----EECGLRM--ELD-SPRSTW---DLTMKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFED
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTL--
------------------------------------LGNFSFKNMLDVR-VEGDVEVPTM
-------MKVKGTV-----------GLSQSS----------TLEVQ-MLSVAP-TALENL
H-ME------RKLS-ADHPFLKEMREYK--QNLYVVMEVVKA----KQEVTLK---RASN
AI--SKFSLN-LPSLGL------------QG--SVNHKEAVTI-PKGCV-LAYR-VRQ-L
II-YGKDEWGIPYICTDNMPT------FNPLCVL--------------------------
------------------------Q-----------------RQGS---TVQMISG----
-E--MHEDFKT----LKKEVQQETQEVEKLSPVG-RSSLLTSLSHLL--GKKKELQD---
LEQMLEGALDKGHEV---TLEALPKDV---------LLL--KDAMDAILYFLGAL-T---
-----------------------------ELSEEQLKIL-VKS------LENKVLPVQLK
LVES----ILEQNFLQ-----DKE--DVFPLRPDLL----S-SLGEED--QILTEALV--
-----GLSGLEV--QRS-GPQYTW---NPDTCHNLC-ALYAGLSLLHLLSRDS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
ITKKMVRKHV-S-KDMKPIKHPFSAAKFRRLSLFRDR---SHFRFLGLYED---------
-DPIDCSLMDILEPN----------------------------S---P--VPETVVI---
--------------------------------------EFPISDTEIKM-QKA--GVGVN
-XXXXX--XXXXXXX---------XX--XXX----------XXXXX-XXXXXX-XXXXXX
X--X------XKLLDPEPSFLTYYRRRG--DDLYVVTETIEL----INPAVLH---ENSS
VVWGK--PVPWNTYV------EX-XXX-XXX--XXXXXXXXXX-XXXXX-XXXX-XXX-X
XX-XXX------------------------------------------------------
---------------XLTRILK-------D-----VSG--LPGYER---FYICPIGRIEE
-P--FWQDFKQ----LQREVSQIMDVLAQFSKVV-RDVLFYNILDML--ENREALYR---
LMAMLEL----K---SSESLDGPAGRILNEIRKDSRWEW--VY-KDTILYLLQAI-L---
-----------------------------VLSDTQLDLL-AQS------MKKRILLHQQE
LVRS----ILEPNFKY-----PWF--LPFTLKPELL----S-PLQGEG--LVITYGLL--
-----DECGLKM--EMN-NPKSTW---DLEAKVPLS-ALYGTLLLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q-QE------RKLA-ADHPFLKEVRDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFSPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
IV-KGKDEWDIPHICNENMQT------FPPGGKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFRT----LKEEVQRETQQVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPRDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILAVQLK
LVES----TMEQNFLQ-----DKD--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLSKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFEN
VTRGLARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDLLQPG----------------------------A------SPS-DPSD--
------------------------------------TGNFSFKKMLDAR-LEGEVDVPKT
-------VKVKGTA-----------GLSHSS----------TLEVQ-SLSISA-KALDDL
H-KD------RKLI-PEHSFLQEIKKRG--ENLYVVMEVVET----VKEITLE---NAGK
AS--GCFSLPFFAPLGL------------QG--SIDHKEAITI-PQGCV-LAYR-VRQ-L
IV-KGKDDWDIPHVCNEDMKT------FPPEGEIPMAETVHPLT----TQ----------
-------------------YSSV---------------------SS---IFSTYTA----
-E--IPENFGS----LKKEVQNEAQEVAKLSREG-QESLLKSLRSIL--GKKQDLQD---
LELTFEEALNKGHPV---SLEANPKDI---------ELS--GDVVEGILYFLGAL-T---
-----------------------------ELSEAQHKLL-AKS------MEMKLLPLQLK
LVES----VMEQNFLQ-----TEE--GLFPLKPELL----S-SLGDEE--LTFTEALV--
-----GLSGLEM--QRS-GPKYNW---DPDTLPQLC-ALYASLSFLQLLTKYS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------VFGI

PF04598 // ENSGT00530000063218_Domain_2 (118, 165)

FEE
ITRIVVKEID-AGGDMIAVRSLIDADRSHCFHLVEEKRT-----VFGYG-----------
--DK-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDSK-GKLI------
--------------------------GSHDQ----------KIEIS-ENWISQ-QYLDTL
E--N------RKLKRELPFSFRSINRTD--SVINLVTETLEM----VKKETLK-------
--SDRQYKFGNEIFQ---SHL---SY------EHKV-RI-----LGGRN-CED-------
-----------SEITLP---------------LSAEK-----------------------
----DG

PF04598 // ENSGT00530000063218_Domain_1 (547, 795)

ASSC----------LGKG------------------------------DS--Q-
SL--GSEDSRN----MKEKLENVESVLQELTEDK-RKDVLNFLTKCL--GREELWQD---
LEQKISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--GARAEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHD--VDCDPE----------------------------
-------------------------------ARIPC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FDR
ASKDVVKKLQ-G-RDLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PKPFIHVQSTD-LEA--NLNVA
-----D--IARGGVG---------YVGYGGY----------NIEVQ-STSIPN-PKLEIL
Q--N------RKLLDNLPTFMKFCRMER--KNLYVVTEAYEV----SKDTMLT---GLSS
VNLSVKGFFKQLFKV------RG-KA---GR----SEKYSIPI-PKGSV-LAYK-KQQ-L
VI-ENNT-CVILPSAT-KK-----KMTFPGTPKYASA-S-EPTEI-YRT-----------
---------------------------------------ELQGLWI---NDIVPIGRIQE
-P--AHLDFMC----LQNEVYKQTEQLAELSKGV-QEVVLSSILSMLYEGDRKVLYD---
LMNMLEL----N---QLGHMDGPGGKILDELRKDSSNPC--VDLKDLILYLLQAL-M---
-----------------------------VLSDSQLNLL-AQS------VEMGILPHQVE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLRKANSSSKPSL
RPGYI------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAST

PF04598 // ENSGT00530000063218_Domain_1 (118, 364)

FEG
VVKRVIRELD-HGGKLIPVDSLQSSAGFQPYCLLRRKLP--MSRFQKVR-Y---------
-TGINLSIRDILEPG----------------------------A---P--EPDVKQST--
--------------------------------------PIRVFDCTDGE-ALGGGELEAA
GQG-----RLAGKAS---------VSEYLRI----------SMKVC-TRKVDP-NVWDAM
K-RESPHLCSHRAT----DVLLYWDERG--KRPK----TFRP----PNEGEVG---ASR-
-PAPGLLRSPARPAG------PG-RG---PG--C-HRKLTGTG-PHKRT-LLFR-RRR-V
TV--RSD-NS--------SRS---PGM----WVGTHFC---------PLGVCPSQP----
--------------------------------------GFSKVSPN---PLAA-DQFAEV
GPAFT-GDFQD----LQAEVWAHVRALRGLSREL-CGQLLAGVAQVL--REERGLQT---
LGDELEQGLSCG--VV-PTLEGPAGAVLECLVNSSGELE--GQLARPVLYLAEAL-A---
-----------------------------VLTETQHAVL-GKM------LETGELSGRLD
LVGS----ILEQS---S----PWQQRRDVSLPPELL----G-SGWG-P--ETPAWVLL--
-----EECGLEV--QAD-APQVRW---EPEAQDLTC-ALFACLVLLLGLSPDSC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------PSVRFLTLSKMN----ITKAEALQK

PF04598 // ENSGT00530000063218_Domain_1 (301, 487)

-ITI------GGGF-----------HAFQES----------EVNVV-PYRTAQ-GYLESL
R--I------RKLKNELPPSFQLIHDM---EDLYLVTQILES----EKEETLK-------
--STKHHTIWIKIGL-------W----------SEN-EATVTI-PP-QV-LGCR-VQQ-L
FF-PQEG-VRGKFLDIC---------------LNE-------------------------
--------------E-----NSFPQ---------------XXXXXX--------------
------XXXXX----XXXXXXXXXRVLKAL--EE-QQNVLSCLKKCL--HDDEKLHV---
LQQRVSEVWVSH----SLQMKVPMGPLLGSLFNDAGILV--EECTEIILDFLAAL-M---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------ILFL

PF04598 // ENSGT00530000063218_Domain_1 (596, 864)

GRIEK
-R--FGQEFKH----LQEEVSRQMEELAQLTKGV-QDVLFHNIPAML--GDQGALQE---
LMDMLEQ----E---PLGHLSGPGGTILNELRKDSSYLR--VNPKYPIIYLLEAI-L---
-----------------------------VLSDIQHDLL-AQS------KEKRILLHQRE
LVRS----ILEPNFSY-----PWN--IPFTLKPELL----A-PLQGEG--LAITYGLL--
-----EECGLKM--QLD-SPRSTW---GLEAKKPLS-ALYGTLSMLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEG
VIRSVVRELD-HGGDLIPVDSLQSSTSFQPYCLLGRKLS--RSWFWKPR-Y---------
-KCINLSIRDILEPD----------------------------A---P--EPAVKLSA--
--------------------------------------PIHVYDSMDGE-LQGSGEVAAP
GQG-----RLAGGAA---------VFDNFSI----------SMHVH-TLRVDP-NIWDAM
K-KERPTPRHRRLRQPEHKVLQQLRNCG--NDVFVVTEVLQT----QKEVKVT---RTQK
HEGSGQFALPGALSF------QG-QG---QG--HRSRKKTVTI-PSGST-LAFQ-VAQ-L
LI--DSD-WDVLLFWDKKHKK---PRTFGLPEADHPWNLGGRPF--LPPGLCPSQP----
--------------------------------------GLSRVSPS---PLSA-DRFAED
WSAVT-GDFQG----LQAEVGAQAQILQGLSQEL-CGRLLAGLVQVV--REESALQT---
LEDVLEQALRCG--SV-APLDGPVGALLECLVHSSRQLE--EQLALPVLYLVEAL-A---
-----------------------------VLSETQHRLL-TEM------LETADRSGQFK
LVRS----VLEQS---T----PWRERRDVSLPQGLL----E-SSWG-P--EAPAWVLL--
-----EECGLEV--QAD-APQVCW---EPEAQGRTC-ALYACLTLLLGLSQDCC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPTVFES
ITRAVVKEMD-TSGEMIAVRSLGDADKFRCFYLVKKRRR-----FFGYQ-Y---------
-VKTNLTLKDI---L----------------------------ESEVP--FDMVVPEFQG
DLPDSGIKPASAALPEDSLPLSHLGNPHIKGQ-GD---NFEILDVVDSK-GSLTVRFHPQ
-MTFKI------AF-----------HIFQEK----------NIKLE-KSEIPQ-EFLDSL
K--N------KKLKKELPPSFQSIQAKR--EDLYLVTETLKT----KEKDTLK-------
--YETQFDFQSLLKM---FGF---QC------EHKH-QKEVTI-PPEKV-LAYR-VKQ-L
VF-PSAE-RM--------------------------------------------------
-------GKL-------------------------------EGGGQ------FNWG--K-
SL--S

PF04598 // ENSGT00530000063218_Domain_1 (606, 794)

LENFQS----IKERVQDMVRVLQDLTPEE-QKGVLNCFTKCL--SSDEELQD---
LEQRVSEIQCSG----ELQMNSPVNSLISSLFNAAGVLI--EARAETIWDVLDAL-M---
-----------------------------ELSEY-RQFV-AEA------LDKGTLLHMKD
TVEP----ILKKNWGE----GPLD--VSCDPE----------------------------
-------------------------------AWTLC-AFYVVVSILLQLGEKPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------N------SPS-DPTD--
------------------------------------TGSFGFKNMLDAR-VEGEVDVPRT
-------VKVTKTQ-----------RCCPAS----------EQGERASTSVLP-QN-ALS
S-CL------RKLA-ADHPFLKEMRDRG--ENLYVVMEVVET----VEEVTLE---RAGK
AD--GCFSLPFFAPLGL------------QG--SVNHKEALTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDDMQT------FPPGVNEPGRE----G-----------------
----------------------L---------------------SA---TFTVPIG----
-G--VHEGFKT----LKEEVQRETHEVEKLNRVG-QSSLLSSLTRLL--GKKKELQD---
LELELEGALDKGHEV---TLEALPKDI---------LLS--KEVMGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------VEKKILPVQLK
LVEN----TMEQNFLQ-----DKE--GVFPLQPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETV
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFRT----LKEEVQRETQQVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLL-----DKE--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFRCFHLVGEKRT-----FFGCR-H---------
-YTTGLTLMDILDT-----------------------------DGDKW--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDST-GELIVRLPKE
-ITI------SGSF-----------QGFHHQ----------KIKIS-ENRISQ-QYLATL
E--N------RKLKRELPFSFRSINTRE--N-LYLVTETLET----VKEETLK-------
--SDRQYKFWSQISQ---GHL---SY------KHKG-QREVTI-PPNRV-LSYR-VKQ-L
VF-PNKE-T---------------------------------------------------
------MNIHFRGKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--G

PF04598 // ENSGT00530000063218_Domain_1 (606, 795)

SEDSRN----MKEKLEDMESVLKDLTEEK-RKDVLNSLAKCL--GKEEIRQD---
LEQRVSEVLISR----ELHMEDPDKPLLSSLFNAAGVLV--EARAKAILDFLDAL-L---
-----------------------------ELSE-EQQFV-AEA------LEKGTLPLLKD
QVKS----VMEQNWDEL-ASSPPD--MDYDPE----------------------------
-------------------------------ARILC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

-----------------MRSCTVFLCLVKN-----LNSFPMCVSFSWGKTSRTC------
---------EKLPTFFSLP-------------------S--ELCAPLLCTPSKMASL

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FER
VSKNLVKELG-D-KDLKPVKSPLDTNKFRQFALLRKKR-KTRTEFWEKPD----------
-VSAECSLMDILEPS----------------------------S---L--VPETVVTG--
--------------------------------------PFHFKDKVIAM-ESV--HMDVT
-AGLEV--SVLGEA-----------AQSHGS----------SLEFR-SVAIPP-TTWEGL
Q--K------RKVLEKKL---VKYRDAG--QNLYVVTEAVEL----INGTVLQ---DKSS
ITALGKFLLPWTTYV------QS-KV---EG--GRVRDTTLML-PSGTV-MAYK-KKQ-L
VF-QEPG-WDILLIPDER------QETFPDEFQERTL-----------------------
----------------------------------------------------VLSDTRRG
PI--LPVDFQY----LQEEISWETEALAQLSKDS-QNDVFHTILKNLKLKDRGTLQD---
LMDMLDR----D---PLGPVDSSGGTFLSKMQEDPRNPW--LQSRSHIMYLLEAI-V---
-----------------------------ALSDTQHELL-AWS------MEKRILLQQRE
LVRS----ILEPNFRY-----PWS--IPVRLQPELL----A-QLQEEG--VAITFALL--
-----EECGLRV--EPG-NLKATW---DLEVKKPLC-ALYAALSGLQQLVVA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------CR

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFKK
ITQKVAKQMD-PKGDLVPVHSISDQDHFRLLCLVRRKRK--ARFRPFPS-Y---------
-RRTEYRLHDVLLPG----------------------------E---E--N---------
-------------------------------TDGHSPRQFTTTGSVRDS-VDGTLSIPTE
-P---AEVELGGAA-----------SVSKQW----------HIKLE-KKHILV-PKLEAL
R-EE------RKIN-MKHTFIEQLRKAR--QNLYVIHETIET----SEEARYE---ESTE
AEAKFMAQLY--A------KFSD-QG-------TTGSKQSITI-PRGCT-LAFR-AMQ-L
TI-GDAM-WGINHFPESNQP------TFVSDGL---------------------------
---------PHLKQE-----YLVTF---------------WFAGFA-----PREVD----
--------------AVEKEAKEKCHILSQLADEL-NAIIVKSIKAVM--RDRNLLEE---
LTEKMEALLDDPDNCELTTQSPDLEVLLSTLKISARCDL--LSLTEAISYTLDAF-S---
-----------------------------ELTEDQLLLL-LES------WEVKIVPQQLK
LVRS----ILEQNAEH-----ST---A-AGL---LP----SFSQQQQQ--QQLTTAVL--
-----EMSGVEL--QGS-SAAVCK----EENFPSLA-ALYAALHALHCLGAS--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLVKEIG-S-KELTPVKYLLNATKLRQFVILRKKKD-SRSSIWGQSDY---------
-IPVEFSLNDILEPS----------------------------S---S--VPESVVTG--
--------------------------------------PFHFSDIVIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSG
VNILGKIS-LWITYG------KG-QGQ-GES--LRVKTKALTL-QKGMV-MAYK-RKQ-L
VI-REKA----ILISDDDE-----QRTFEDEYKISES-VFYCAAR-SEEWLPSIHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDIQQDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRKKKD-SRSSIWGQSDY---------
-IPVEFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIVIQK-HKA--DVSVN
-VGVEV--SVSGET-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAIEL----INNTVLY---NSSG
VNILGRIS-FWITYG------KG-QGQ-GES--LRVKKKVLTL-QKGMV-MAYK-RKQ-L
VI-REKA----ILISDDDE-----QRTFQDESKISER-VFYCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLSQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SPGHLDGPGGAILKKLQQESNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDIQHDLL-ACS------VEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELY-NPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSSLFLR
STKSLVRELG-RKGELVPVDSLNSSQRLRPFCLVRKKHKH-SLWPWDTP-L---------
-IPTDFSLLDVLEPG----------------------------C---P--DPEVNHS---
-------------------------------------KPIYSWEKEAEG-LTGAVSVS--
-AGLQS--QVTGSG-----------TTTCLS----------ALAVQ-TLWVSP-FTWEML
L-EK------RKLRSPRPSFLQELQSRKERESLYVVTEAVET----LQDTILQ-S-HDQM
R-GAGQLSL-----LQLG-HVQV-QG---QSH-VDTE-KMVSI-PQGSV-LAYR-VLQ-L
VV-EEDG-WAVLYFPER-------------------------------------------
---------KLCRN---------------------------ARVAI---

PF04598 // ENSGT00530000063218_Domain_1 (590, 790)

AFSQESGE---
E-----SNFYS----LRDQADSQLQDLVTLSSER-RATLLGALQELL--RDQQALQE---
LEDTLEQALDTG--L-LAQLEGPGGCVLCILQDSTSNLS--CSKGRAILYILGAL-A---
-----------------------------ALSEPQHCLL-AQS------IERQILSEELE
LAQE----LCKSICDM-----LTR--VLLLYGGKVRPQGEV-ALQGNT--GQAVLPCVSC
IGLLRSICHM-T--KQN-K-LLRF---QP--IVPMT-IQCQSMGSSQLNK----------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
LVRRVVQELD-HGGALIPVTSLQSSTAFKPYCLVVRKPA--RSWFWKPR-Y---------
-QHVNLSIKDILEPD----------------------------A---P--EPVLQHDG--
--------------------------------------PFHIHDTVDGQ-LRTSVEVAAP
GEG-----KVAGGAS---------VSDSSST----------SLNVF-SLSVGP-NTWQAL
L-QE------RHLRQPEHGVLQQLRCRG--DNVYVVTEVLQT----QKEVEVM---RTHR
QEGWGLLSLAGAMCL------QG-EG---EG--HLSQKKTVTI-PSGSI-LAFR-VAL-L
VI--HSD-LEVILFPDKKQKT------FQPPPTGYRPFSSEGSG--R-------------
--------------------------MD----------LSMRGCIG---NFQT-DGVPAN
ETVTED--FQG----LQAEVEAVSKELALMDGQL-CQQLLEGLERVL--RDQLALQA---
LEEALEQGLSS---GPVEPLGGLADAVLDCLVSPSRMLV--PELAVPVVYLLGAL-N---
-----------------------------TLSKAQHQLL-VEA------VALKTLSRQLE
LVGS----LLEKS---A----PWQKRSTLSLPPELL----K-SGWG-G--ETPAWILL--
-----EECGLEL--RED-PPHVHW---EPQAQGRVC-ALYASLALLSQLSQEPR------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 487)

MFEN
ISKNLVKELG-D-KDLTPVKHLLNANKFRQFAILRKKK-KTLSQFWELPD----------
-IPVEYTLMDILEPS----------------------------S---S--VPETVIKG--
--------------------------------------PFIFSDTMFRK-YKA--SAGVT
-AMLET--NVSGEA-----------TKCHET----------FLQFH-AVTFPP-QNWKDL
L--K------RKVLDQELLFLRKCRGRD--DNLYVVTEAVEL----INSTVLH---DSSS
VNVLGKCFIPWMTSV------KG-QGQ-GEG--LKVREKMLTL-PEGTV-IAYK-KKQ-L
IF-ENND-GEGAISISAP------CILLPSFH----S-TR---------I----------
--------------------VC------F--------------L-V---YYFYPV---PR
AQ--TWADFKQ----LHEEIFQEMEALAQLSKDT-QDSIFHTILNML--GNREALQD---
LTDTLDG----S---PLDLLDDFGGTILNEMQPDTRDLW--IQARFHIIYLLEVI-M---
-----------------------------VLSDTQHDLL-AQS------MEKRILLQQQK
LVRS----ILEPNFKY-----CWD--IPFTLKPELL----A-PLQGED--LAITYGLL--
-----EECGLKM--ELN-SPRSTW---DLETKQPLS-ALYGTLSLLQQLTA---------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

LFEH
ISKNLVRELG-D-KDLRPMRCLSNANQFRQLAILQKRK--KRSPFWEQPD----------
-IPAEYTLMDLLEPS----------------------------S---S--VPETAVMG--
--------------------------------------PFLFSDTVVQQ-GQV--SANVT
-TGLEM--NVSGKA-----------TVFHGS----------SLQFQ-AVTIPP-HNWKDL
Q--K------RKVQDPELLFLVKCRDRQ--DNLYVVTDTVEL----TDTTVLC---DNRS
VNVWGSCFLPFDTFF------KG-RGQ-GEG--LKVREKTLIL-PQGTV-MAYK-RKQ-L
VF-KENG-WDILISDDDK------EKTFPEEKLRMQS-KS----L-PSEW----------
--------------------VI------FE----------PGTINS---GFIPPRGRTQE
PF--RQEDFKQ----LHEEIFQEVEALDELSKDT-QDAIFHNILNTL--GNRKALLE---
LMDRLDG----D---PFDPLDGFGGEILNETQEDTRNLW--IQGRSSIIYLLEAI-I---
-----------------------------VLSDTQHNLL-AQS------MKKRILLQQQE
LVRS----ILEPNFKY-----PWN--IPFTLKPELL----A-PLQGEG--LAITYGLL--
-----QECGLNI--ELN-SPRSTW---DLEVKQPLS-ALYATLSMLQQLAGSQRGQ---A
LPVYTGSV---------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLQPG----------------------------S------APS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALEAL
H-EE------RKLT-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGRDEWDIPHICNDSMQT------FPPGEMPEEKF----------------------
--------------------------------------------TR---WTNHPLG----
-E--AHEDFKT----LKEEVQRETHEVEKLSREG-QSSLLSSLSKLL--GKKKELQD---
LELMLEGALDKGHEV---TLEALPKDV---------LLS--KEAMGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MEKKILPVQLK
LVES----AMEQNFLQ-----DKE--GVFPLRPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPHLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLVPLDSLIDFKRFHPFCLVLRKRR--STLFWGAR-Y---------
-VHTDYSLLDLLEAG----------------------------S------SPE-EPTD--
------------------------------------SGNFGFTNMLDAR-VEGKVDMPKT
-------VKVTGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALESL
Q-EK------RKLE-EEHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--AGFSLPFFAPLGL------------QX--XXXXXXXXXX-XXXXX-XXXX-XXX-X
XX-XXXXXXXXXXXXXXXXXX------XXXXXKSEEKFVX--X-----------------
----------------------X---------------------XX---XXXXXXX----
---------------XXXXXXXXXHRKTKVGSRGPSARIFLLLSGKL--AKNQVIQD---
LDSALEGALDKGHKV---TLEALPKDV---------LLS--KEATGAVLYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------TEKKILPVQLK
LVES----TLEQNFLR-----DKE--GVFPLQPDVI----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYASLSLLQLLTGAS-------
-----------------------------------------------

------------------------------------MISAHCNLRLPGSSDSP-------
---------------------AS-ASGVLPGRPDAPLG--------------SMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-HSGELIPMTSPKDSPGFQPYFLVFRKPS--SSWFWKLC-Y---------
-KPLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDTVDGQ-LRGGVELSAP
GQA-----KITGGAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLQQPEHKILQELRSRG--DNVYVVTEVLQT----QTEVEVT---QTHK
REGSGKFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SV----------LSMMGCLH---NFSA-DGVPAE
GTFTED--FQG----LREEVEAISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGLSL---GPVESLDGPAGAVLECLVLESRMLV--PELAVPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTVSLPPGLL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 897)

VFKT
ITRAVVQELD-AGGDMIEVRSVLDADKFHCFCLVMEMNT-----RL----C---------
-YRTDLTLEDILESD----------------------------KGEGQ--CDELDSGLP-
------------------------------GS-KA---ALQAVDVVDST-GESTVKLPRG
-ITV------EGAF-----------QESHRH----------DITML-WSRTSSHIWIPSR
T--V------QKLKKKLPTSFLSMRTRG--EDPYLVTETLGT----TKKETLT-------
--SERQFKFWSLLKF---FNL---KY------ECKRSPKAVTI-PPKLV-LGYR-VKQ-L
VF-PNME-RMTVYFGGR-------------------------------------------
------IDIC-----------------------------------------SFPEG--K-
SL--NLEDLRN----MKEKVQDTVSGLQDLPEEE--RDVLSYLTKCL--TTDEGLKD---
LDEKVSKVLTSG----ELQMEGPAGPLLSSLFNAAGILV--EACVEAILEFLEAL-K---
-----------------------------ELSE-EKELM-AET------LKKGTLPLMKD
QVES----ILEQNWGEQ----P--------------------------------------
-------------------------------CDTLY-ALFVAVFILLQLSEKPASVPS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MLER
ISKNLVKEIG-S-KDLTPVKYLLSATKLRQFVILRKKKD-SRSSFWEQSDY---------
-VPVEFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DIGVN
-VGIEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---DSSS
VNILGKIA-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYEISEM-VGYCAAR-SEGLLPSFHTISPT
LFNA-SSN-DM---KLKPELFLTQQ---FL-----SGH--LPKYEQ---VHILPVGRIEE
-R--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--RDRGALQD---
LMNMLEL----D---SSGHLDGPGGAILKKLQQDSNHAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDFQHDLL-ACS------VEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DVEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------HHVGQVDLELPTSGDPFGHL---R
--------------------GIP-LAGQLPGRPDAPL--------------GSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-HSGELIPMTSPKDSPGFQPYFLVVRKPS--SSWFWKPC-Y---------
-KPLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRGGVELSAP
GQA-----KITGGAS---------MSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLQQPEHKILQELRSRG--DNVYVVTEVLQT----QTEVEVT---QTHK
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SV----------LSMMGCLH---NFSA-DGVPAE
GTFTED--FQG----LREEVEAISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGPSL---GPVESLDGPAGAVLECLVLESRMLV--PELAVPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTVSLPPGLL----G-SCWG-E--GAPAWVLL--
-----EECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 513)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-TALENL
H-KE------RKLS-ADHPFLKEMRERG--ENLYVVMEVVET----LQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SMNHKEAVTI-PKGCV-LAYR-VRQ-L
MV-NGKDEWGIPHICNDSMQT------FPPGEKPGEGKFI--------------------
--------------------------------------------L----IQASDV-----
------------------------------------------------------------
------------------------------------------------------------
-----------------------------VLSEAQQKLL-VKS------LEKKILPVQLK
LVES----TLEKNFLQ-----DKE--GVFPLXPDLL----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTRPNLC-ALYAGLSLLQLLSKDX-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTFLDILEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLL-AEHPFLEEMRSRG--ENLYVVMEVVEA----VQEVTLE---RAGR
AE--GCFSLPFFAPLGL------------QG--SVNHREAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHIYNDNMYT------FPPGEKPEDEKFT--------------------
---------------------------------------------L---IQASDVG----
-A--VHEDFRT----LKEEVQRETWEVEKLSPEG-KSSLLSSLSKLL--GKKKELQD---
LELTLEGALGQGHEE---ALEALPKNV---------LQS--KGAMDAILYFLGAL-A---
-----------------------------ELSEAQQKLL-VKS------VEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPELF----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFER
VVQGVVRELD-HSRKLIPVDSLHSSTCFRPYCLVSQKPS--RSWFWKPR-Y---------
-TSVNLSIKDILEPD----------------------------A---P--EPDLERDG--
--------------------------------------PFHFSDDVDGE-LKGSVELAAP
GQG-----KISGGAA---------VSGSSST----------SINVC-TLRVDP-NIWEAM
H-QE------RRLRQPEHKILKQLRSRR--DNLYVVTEVLQT----QEEVQVT---RTHK
KEGSGQFILSAAMCL------QG-EG---QG--HLSQKNTVSI-PAESI-LAFR-VAQ-L
VI--THD-WDILLFPDERKTT------FPPPSTGEDEAQPGPRA--GGGG----------
---------------------------A----------C-SFGQA-----FSW-AQRTGG
RELPEAWDLQG----LQAEVEAVSEELQHMETEL-KRQLLGPLGAVL--RDEPALQA---
LEDSLDQGLCCG--GQVEPLEGPAGAILEYLVLPSRVLA--QELATPIFYLLGAL-M---
-----------------------------VLSESQHQLL-AEA------LETDTLPEQLR
L--Q----VLEQS---A----PWHMPGVVSLSPDLL----G-RGWG-E--EAPAWALL--
-----EKCGLAL--QVP-APQVRW---EPQAQGPAC-ALYASLALLSRLSPKPC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSI

PF04598 // ENSGT00530000063218_Domain_1 (118, 849)

FKM
VTGKVVRELN-ENGDLIPIRNLIDADKFHCCSLVCKKKS--FFPFFKPH-Y---------
-WKTGLTVDDLLEAS----------------------------V---------FSSE---
---------------------------------VAEKKNSRIKDNVKMK-MRTEMNIPHV
-T------SVNGEV-----------DFSTRL----------ELKLK-FWEISQ-EGKESL
S--Q------RKLKKEMPSLVEALKKRG--ENLYMVIETVEL----AEEQSVE---RANI
SQPAFLPPFYFYFSS---------QG-----CVDVSISSAVTI-PSKSV-LACR-INL-L
VF-EEKH-CQIKCCHKYE--------LFL-------------------------------
--FSFSLGISHFDDK-----NSFSS---------------EAGAKA-----VNHSKQVS-
AE--GVEG--------------VSQAIKELVRAP-RRKLHEG----L--RKGA-GRR---
QEAG-DASLRLKKGMGAGEREKTKLPRLP----KELIIY--HNSAEGILDFLEAL-T---
-----------------------------ELKEEQQKIL-PKV------VEKGLLSETMK
LVRK----SMRKGHPA-----KSE--GEIRTKPLLA----A-SVTGKA--DSITHTLV--
-----GICDPEG--KL--EQPVTW---DSETCHSLC-ALYTVLSVLMLLAQGS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VREVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAIAI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFGT----LKEEVQRETQQVERLSQAG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAVGAILYFVGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLHPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------M

PF04598 // ENSGT00530000063218_Domain_1 (698, 864)

LV--PELAIPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEV------LESRSLLGPLE
LVGS----LLEQS---A----PWQEHSTMSLPPGLL----G-SSWG-E--GAPAWVLL--
-----DECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------MISAHCNLRLPGSSDSP---ASAF
--------------------QLL-LPGRLPGRADAPPSGR--------RQSRSMGSAFER
VVRRVVRELD-HGGELIPVTSLQSSAGFQPYCLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------SFHFYDAMDGQ-LQGSVELAAP
GQA-----KIAGGAA---------VSDSSST----------SMNVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKILQQLRSRR--DNVYVVTEVLQT----QKEVEVT---RTHK
REGSGRFSLPGAMCL------QV-CS---Q--------------------------PR-L
VI--NSD-LDVLLFPDKKQRT------FQPPPTGHKGSTSEGAW--PQLS----------
--------------------------SG----------LSMMGCLP---NFLT-DGVPAE
GTFTED--FQG----LRAEVETISKELELLDRDL-CQLLLEGLEGVL--RDQLALQA---
LEEAVSGGGCP---GHTRPAQPARGPLL-----ESGLGV--PESTFPHGI----------
--------------------------------PSPWGAH-REA-----

PF04598 // ENSGT00530000063218_Domain_1 (769, 864)

-SSSQTLLGPLE
LVGS----LLEQS---A----PWQERSTMSLPPGLL----G-SSWG-E--GAPAWVLL--
-----DECGLEL--GED-TPYVCW---EPQAQGRMC-ALYASLALLSGLSQGPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSLFER
EAKNVVKELG-QK-QLKPVTSFHSSTQFRPFCLLRKKTKNIFTLFWEKP-P---------
-IPTDFSLMDILEPS----------------------------S---T--DPGTAV----
-------------------------------------GPFNFSEKVDEQ-LHTDVDVF--
-AGVKM--EVSGGA-----------MMSHSS----------SLEMQ-ILTVPH-HMDNS-
A-EG------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXX-----XXXXXXXXX-XXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXX----X---------X
XXXX-----XXXXXX-----XXXXX---------------XXXXXX---XXXXXXXX---
XX--XXXXFQS----LQREVNFQKTEFVSM--PG-KEDLLSALHDLL--GNRNALQD---
LEDMXXXXXXXX--X-XXXXXXXXXXXXX----XXXXXX--XXXXXXXXXXXXXX-X---
-----------------------------X

PF04598 // ENSGT00530000063218_Domain_1 (751, 864)

LNDTQHNLL-AQS------LKKKILPQQLE
LVQS----ILEANFNQ-----FHR--CPFLLQPEFL----S-SLHGED--LTITIGLI--
-----EKCGLKL--QKA-DQLLIW---DPDERNHLC-ALYGALSCLLSLAED--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-IRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLM-AEHPFLKEMRSRG--ENLYVVMEVVET----VQEVTLQ---RAGK
AE--GCFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCI-LAFR-VRQ-L
VV-KGRDEWDIPHICNDNMQT------FPPGV----------------------------
-------------------------------------------------IQASDVG----
-E--VHEDFRT----LKEEVERETQEVEKLSPRG-RSSLLCSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LPS--KEAMGAVLYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKNILPVQLK
LVES----TMEQHFLQ-----DKE--GVFPLQPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPHLC-ALYAGLSLMQLLSKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MLY

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFDQ
VSKDVVKKLQ-G-KDLRPVRCLSDATKFRQFDILQKTP---QSLFFKSED----------
-TPVGYSLLQILEPN----------------------------F---P--VPETEVSA--
--------------------------------------PMPLKHITSQK-WKA--DVDVK
ATIADG--GASAEF-----------VQSCGY----------DIEVQ-SRSIPD-SKLESL
Q--N------RKLLDKKLSFVTDCQMGR--NNLYVVTEVFEV----TKDTVVQ---GSSS
IDLSGKALVSQLVKG-------E-AQG-Q-W--QRETTDLVPI-PKGAV-LAYK-KKQ-L
VI-ENNT-CAILLSANAKKK------TFPGIFNFGMS-S---------------------
-----------------------------------RSQTMEIGSWI---DYIPPIGRIEE
-P--VHLDFKY----LEKEVFLRKEQLAMLSKDV-QDVVFSNLLPML--SDSDVLFD---
LINMLEL----D---QLGHMDGPAGLILDELRKNSSTPW--IDLKGLILYLLQAL-M---
-----------------------------VLSDTQLDLL-AQS------MEMRILLQQRE
LVRS----ILEPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----KGCGLKM--EPN-SPRSTW---DLEAKMPLS-ALYGILSCLQQLVEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEE
VVKSVIKEVD-RKGELIPVDSLRNSTSIRPYCLLSRKLS--SSWFWKPR-Y---------
-RCVNLSIKDILEPN----------------------------A---P--EPEPECCG--
--------------------------------------RFCVSDAVDGN-IQGRVALEST
GQG-----KISGAAA---------MSGSCSA----------SINMC-LLRVTQ-NTWNVM
Q-HE------RQLQTPEHKILEQLRSRG--DDVFVVTEVLQT----EEDVQVT---QTLS
KEGLGQFALPGAVCL------QG-EG---KG--YLNQKKMVTI-PAGSI-LAFR-VAQ-L
LI--DPK-WDILLIPNEKKRT------FELPPSSHRREDGQRQH--AFNLLA--------
--------------------------TL----------RSM-GERL---KLLT-DGTHEE
QVTR--EDFQG----LRTEVEAASTELGHLEMEL-RQQLLMDIGRIL--HDQPSMEV---
LEASLEQGLCHG--RQMEPLDGPAGSILEYLVLPSGELV--PELAAPIFYLLGAL-T---
-----------------------------VLSETQQQLL-AKA------LETTVLSKQLE
LVEH----ILEQS---T----PWQEQRFVSLAPRLC----G-NSWD-E--EAPTWVLL--
-----EECGLTL--QVD-TPQVHW---EPKSQGPTC-ALYASLALLSSLSQKPC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFHCFHLVGEKRI-----FSGCR-H---------
-YTT-------------------------------------------R--LDELDSGLQ-
------------------------------GHQKT---EFQILDNVDSK-GKLIVKLPKK
-ITI------SGSF-----------QGSHDQ----------KIEIS-ENRISQ-QYLDTL
E--N------RKLKRELPFSFRSINRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNQIFQ---SHL---SY------EHKG-QREVTI-LPNRV-LSYR-VKQ-L
TM-NKQR-LMGNRI----------------------------------------------
-------------------------------------------GS------

PF04598 // ENSGT00530000063218_Domain_1 (592, 795)

PKHTT--K-
SL--GSEDSRN----MKEKLENMESVLQELTEDK-RKDVLNFLTKCL--GREELRQD---
LEQRVSEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--EVHAEAILDFLDAL-L---
-----------------------------ELSE-EQQLV-AEA------LEKGTFPLLKD
QVKP----IMEQNWDEL-VSSPHD--MDYDPE----------------------------
-------------------------------ARIPC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------

PF04598 // ENSGT00530000063218_Domain_1 (616, 795)

MTEKLENMESVLQELTEDK-RKDVLNFLTKCL--GREELWQD---
LEQKVSEVLIFG----ELQMEDPVNRLLSSLFNAAGILV--GARAEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHD--TDYDPE----------------------------
-------------------------------ARIPC-VLYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------MISAHCNLRLPGSSDSP-------
---------------------AS-ASGVLPGRPDAPLGPPTGTM--------SMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-HSGELIPMTSPKDSPGFQPYFLVFRKPS--SSWFWKLC-Y---------
-KPLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDTVDGQ-LRGGVELSAP
GQA-----KITGGAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLQQPEHKILQELRSRG--DNVYVVTEVLQT----QTEVEVT---QTHK
REGSGKFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SV----------LSMMGCLH---NFSA-DGVPAE
GTFTED--FQG----LREEVEAISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGLSL---GPVESLDGPAGAVLECLVLESRMLV--PELAVPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LASQTLLGPLE
LVGS----LLEQS---A----PWQERSTVSLPPGVL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPHVCW---EPQAQSRTC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 781)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALETL
R-EE------RKLE-ADHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LTFR-VRQ-L
MV-NG-DEWDIPHIYNDNMQT------FPPEGKPEEKLTR--------------------
--------------------------------------------------PRRAAW----
-E--VHEDFKT----LKEEVQRETKEVEKLSQAG-QRSLLSSLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKAV---------LLS--KDVMGAVLYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
L-----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MLER
ISKNLVKEIG-S-KDLTPVKYLLSATKLRQFVILRKKKD-SRSSFWEQSDY---------
-VPVEFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DIGVN
-VGIEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---DSSS
VNILGKIA-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYEISEM-VGYCAAR-SEGLLPSFHTISPT
LFNA-SSN-DM---KLKPELFLTQQ---FL-----SGH--LPKYEQ---VHILPVGRIEE
-R--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QNVVFYSILAML--RDRGALQD---
LMNMLEL----D---SSGHLDGPGGAILKKLQQDSNHAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDFQHDLL-ACS------VEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DVEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFED
VTRALIKQLN-PGGDLTPLTSLIDFKRFHLFCLLLRKRK--STVFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTL--
------------------------------------LANFSFRNMLDAR-VEGDVEVPKT
-------VKVKGAA-----------GMSQSS----------TLEVQ-TLIVDP-TTLENL
N-KE------RKLS-ADHPFLKEMREYK--QNLYVVMEVVEA----KQEVTLE---RTSN
AN--AIFSLPSFAPLGL------------QG--SMNHKEAVTI-PKGCV-LAYR-VRQ-L
MV-YGEDEWGIPHIYTDNKPT------FIPLCVP--------------------------
------------------------Q-----------------RQGL---TVWKLSG----
-E--MHEDFKT----LKEEVQRETQAVEKLSPVG-RSSLLTSLSHLL--GKKEELQD---
LEQTLEGALDKGQEV---TLETLPKDV---------LLS--KEAMDAILYFLGAL-T---
-----------------------------ELSEEQLKIL-VKS------LEKKILAVQLK
LVES----ILEKNFLQ-----DKE--GVFPLQPDLL----S-SVREEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---DPATRPHLC-ALYAGVSLLHLLSKDS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------TGNFGFKNMLDTR-VEGDVDVPKT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALETL
Q--E------RKLA-ADHPFLKEMQDQG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--ACFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCV-LAFR-VRQ-L
MV-KGKDEWDIPHICNDNMQT------FPPGEKSGEEKVI--L-----------------
-------------------------------------------------IQASDVG----
-D--VHEGFRT----LKEEVQRETQQVEKLSRVG-QSSLLSSLSKLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------LLS--KEAMGAILYFVGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLL-----DKE--GVFPLQPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSLLQQLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ITKKLVKEIG-D-QELRPVKCLVSATKIHRFSLIRRKK--ARSRFWQLPD----------
-IPLDVSLMHILEPG----------------------------S---S--VPDTAVEV--
--------------------------------------SADFSDTEVRK-QQA--AGSVN
-AGAEV--GFSEET-----------AACRGS----------SLKYQ-IVSTPH-ETWPEL
Q--K------RKLPDPEPYFLKQCREAG--VNLYVVTDTVEL----LNSPVLQ---DHSS
VKV----SVSPGFCS------QG-KGQ-GRS--LQVKEKKLTV-PKGSV-VAYK-RKQ-L
LF-YSTG-WGIHHIADDNDD----KETFPAVQPKEED-SI--SE--P-KL----------
----------EVSKQLSYLWMHA----------------------------ITSLG-SLV
PL--SRADFQL----LQEEVSQNVKA-AELSKDM-QNIVFSNLLAML--GDREALQD---
LMDTLEQ----E---PFGHLDGAGGTILTELQKDSCHPG--VGSKCLILYLLETL-M---
-----------------------------VLSDIQHVLL-AQS------MEKRILLPQRD
LVRS----ILEPNFNC-----SEN--TPFTLQPELL----A-PLQGEG--LAITYGLL--
-----DECGLKM--ELN-SPGSTW---DPEAQEPLS-ALYGALSVLKQLAEARANLEGRP
RGILGGYI---------------------------------------

------------------------------------------------------------
-----------------------------------------------------MTS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
YVKNLLKEVG-R-EDLKPVRSLSSATKFQQFIMIRKKKGNFFSQFWKQPD----------
-IPTEFSLMDILEPS----------------------------S---S--IPGLQTSH--
------------------------------------ISPKPISSIYQST-HQV--RNKP-
---LAC--VLRGSVI---------QSKERRC----------SF------PSSY-PSLPSL
Y--P------RETLEKEPAFLKECRDKR--ENLYVVTEIMKL----TKNTTLN---KMGH
VNLNIKFF----FKE------LG-QVQ-GEG--LNVRKKTLTL-PKGMV-MAYQ-RKQ-L
VL-KQST-LTILHTPNIPE-----RNIT--------W-A----------FMPQPTAVYPP
------VN-CF---RT--------------------NL--RLVAYT---GDILPIGETQA
-Q--LHDNFNH----LQEEISREMEALASFPKDL-RDTMFHNILAML--GDRGALQH---
LMDMLEE----N---PSGHLDGPGGTILDELRKNTEDPW--VSPKYHILYILGAI-M---
-----------------------------VLSDTQHDLL-AQS------MKMRILAQQRE
LVRS----ILEPNFKY-----PWS--IPFTLKPELL----A-LLQDEG--VAITFGLL--
-----DECGLMM--EPN-IPRSTW---DLEAKGPLS-ALYATLSVLQQL-----------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MLER
ISKNLVKEIG-S-KDLTPVKYLLSATKLHQFVILRKKKD-SRSSFWEQSDY---------
-VPVEFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMMQK-HKA--DVGVN
-VGIEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---DSSS
VNILGKIS-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LGYCAAR-NEEWLPSFHTISPT
LFNA-SSN-DM---KLKPELFLTQQ---FL-----SGH--LPKYEQ---VRILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--RDRGALQD---
LMNMLEL----D---SSGHLDGPGGAILKKLQQDSNHAW--FNPKDPVLYLLEAI-M---
-----------------------------VLSDFQHDLL-ACS------VEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQNEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DVEAKMPLS-ALYGTLSLLQHLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPT

PF04598 // ENSGT00530000063218_Domain_1 (117, 795)

VFES
ISRAVVKEID-TSGETIAVRSLSDADKFHCSYLVKKRRR-----FFGYQ-Y---------
-DKTNLTLKDI---L----------------------------ECEVP--FDMVVPELQ-
------------------------------GQ-GD---NFEILDVVDSK-GSLAVKFHPQ
-MTFKI------AF-----------HIFQEK----------NIKLE-KSEIPQ-EFLDSL
K--N------KKLKKELPPSFQSIQAKR--EDLYLVTETLKT----KRTETLK-------
--YETQFGFQILLKM---FGF---QC------KHKH-QKEVTI-TPEKV-LAYR-VKQ-L
VF-PSAE-RM--------------------------------------------------
-------DICFLDKT-----RSFPE------------------------------G--K-
SL--NLQNFRS----IKETVQDMVRVLQDLTPEE-QKEALNCFTKCL--SSEEELQD---
LEQRVSEVQCSG----ELQMNSPANSLISSLFNAAGVLI--EARAETIWDVLDAL-M---
-----------------------------ELSEY-RQFV-AEV------LDKGELRPVKD
KVES----ILEENRCE----GPLD--VSCDPE----------------------------
-------------------------------ARTLC-ALYVVVSILLQLSEKPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------

PF04598 // ENSGT00530000063218_Domain_1 (372, 864)

KLT-AEHPFLKEMRNRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GNFSLPFFAPLGL------------QX--XXXXXXXXXX-XXXXX-XXXX-XXX-X
XX-XXXXXXXIPHIFNDSM-T------FPPGXXXXXXXXX--------------------
--------------------------------------------XA---RLGHFVW----
-E--AHEDFKT----LKEEVQRETQEVEKLSHAG-KSSLLSSLSKLL--GKRKELQD---
LELEIEGTLDKGHEV---SLEALPKDV---------LLS--KEALGAVLYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVEN----TMERNFLH-----DKE--GVFPLQPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPHLC-ALYAGLSFLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSSL

PF04598 // ENSGT00530000063218_Domain_1 (118, 390)

FLR
TTKSLVGELG-RKGELVPVDSLSSSSRLRPFCLVRKKHRR-HLWPWDTP-L---------
-IPTDFSLLDLLEPG----------------------------C---P--EPEVNRS---
-------------------------------------SPINIWEKVAGG-LSGAVSLS--
-AGLQG--QVAGSS-----------NSACIS----------ALAVQ-TLWISP-GTWEML
L-EK------RKLRSPRPPFLQELQSRKERESLYGDLHIWLQ----TS------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEE
VVKSAIKELD-CNGDLIPVDSLRNSTSFRPYSLLSRKLS--SSWFWKSR-Y---------
-KCVNLSIKDILEPS----------------------------A---P--EPEPECCG--
--------------------------------------RFQISDAVDGN-MQGRVALASI
DQG-----KIAGAVA---------LSGSRSA----------SMNVC-ILRVAQ-NTWEVM
H-QE------RHLQQPEHKILQQLRSRG--DDVFVVTEVLQT----QEEVQVT---RTHD
REGSGQFALPGVTCL------QG-ES---KG--HLSRKKMVTI-PAGSI-LAFR-VAQ-L
LI--DPT-WDILLFPDDKKRT------FELPSSSHRKEDGQKRH--AFNLLT--------
--------------------------TL----------QSM-CVPL---KLST-DAIHEE
QVIT--EDFQG----LRAEVKAGSAELRHLEVEL-REQLLRDIGRLL--DDQPSMEA---
LEASLEQGLCRG--GQVEPLDGPAGSILECLVLPSGDLV--LELAAPIFYLLGAL-T---
-----------------------------ALTETQQKLL-AEA------LETTMLLKQLE
LVEH----ILEQC---T----PWQEPSSVSLPLSLL----G-NSWD-E--EAPTWVLL--
-----EECGLTL--RVD-TPQVHW---EPKSQGPMC-ALYASLALLSSLSQKPS------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------

PF04598 // ENSGT00530000063218_Domain_1 (372, 864)

HLQKPEHKILQQLRHRG--DNVYVVTEVLQT----QKEVEVT---YTRK
REGSGQLALPGALYF------QG-GG---QG--HRSCKKTLTI-PSGSI-LAFR-VAL-L
VI--GSD-WEIIFLPDKKQRT------FG---GDHVFSSLTGDC--PHPPFGFFS-----
--------------------------------------------KC---LLQSDAAHTEN
SLMLA-QDFED----LQAEVEAQAEGLCILSPEL-CQQLLTGLGQVL--RDEMTLHH---
LEELLEQGLCCG--RV-ELQTGPVGDVLECLVQPCRMLE--EELVEHFFYLLGAL-A---
-----------------------------ELNEAQHMEL-AQM------LEARAPLGPCS
LVES----LLEQS---A----PWQKPVPVSLP---L----G-SSWG-P--EAPIWILL--
-----EECGLEL--KAN-APHVRW---VPEALDQTL-ALYACLALLSKLSQSQ-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSSL

PF04598 // ENSGT00530000063218_Domain_1 (118, 389)

FLR
TTKSLVRELG-RKGELVPVDSLSRSPRLRPFCLVRKKHRR-YLWPWDTP-L---------
-IPTDFSLLDLLEPG----------------------------C---P--EPEVNHS---
-------------------------------------SPINVWEKVAGG-LTGAVSLS--
-TGLQG--QVTGGS-----------NSAYIS----------ALAVQ-TLWVSP-CTWEML
L-EK------RKLRSPRPSFLQELQSRKERESTGRYRWGWWQ----HGPVL---------
---------------KLS-WV---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKHFYPFCLVRRKRK--STLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGKFAFKNMLDAR-VEGQVDMPKT
-------VKITGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLA-AEHPFLKEMHDRG--ENLYVVMEVVET----VQEITLE---RAGK
AE--GYFSLPFFAPLGL------------QX--XXXXXXXXXI-PKGCI-LAFR-VRQ-L
MV-R-KDEWEIPHIYNDNMQT------FPPGXXXXXXXXX--------------------
---------------------------------------------X---XXXVCIG----
-E--VHEDFRT----LKEEIQRETQEVEKLSHVG-RSSLLTSLSKLL--GNRKELQD---
LELTLEGALGKGHEV---TLEALPKDV---------LLS--KEALGAILYFLGAL-T---
-----------------------------ELSEVQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--SVFPLQPDLL----S-SLGEED--LTLTETLV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPCLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
DVKKLVKELG-K-GDLIPVQSLLQSTRFRPFCLIRKKAKK-FPWFFEPT-F---------
-FDTYFSLMDILEPS----------------------------S---S--VAEVTSS---
-------------------------------------KPLHFYETEYNE-LKGEMDLNVT
-NEVQG--KVTGAT-----------TSSHNV----------VLKLQ-MLTVVP-QIWEDL
--ME------RKVK-SKHSFLQEVQNRG--EKLYVVAEAIEN----MEDTILM---HSNK
KEGSIQASLGQLLSLLGI-NFKS-QT---QG--QTDGKKGVSV-NQGCI-LAFR-ALE-L
FI-HNDK-WRVTYIPEMQ------------------------------------------
------------------------R---------------RSHVEE---FYIDRLTGKY-
IS--APRNFEE----FQEMMIREQEALSKGSREL-QVTLLHVIQDIL--GNRKALQD---
LEDMLDQVPD-M--REKGQLEGPGVCILKHLQDNSEDAS--NQQTESILYFLGAL-M---
-----------------------------ILTDTQQELL-DQS------LEKRILPQQLE
LVKS----ILKTNFRE-----PGE--SSFSVHPELL----S-ELKDED--QAITMNLM--
-----KECGLNL--ECA-GSQTKW---NREAESSVC-ALYVVISFLQLLTQA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MVS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFDR
VVRSVVRELD-RKGELIPVESLQSATGFRPYGLLSRKPS--SSWFWRYP-Y---------
-KCVNLSIKDILKPD----------------------------A---P--EPDLDRSS--
--------------------------------------HFLFYDATDGQ-LQGSVKLAVP
WQG-----KISGGAS---------VSDSSRA----------SMDVC-ALRVDP-NIWEVM
Q-QE------RRLRQPEHKVLQQLRSRG--NDVYVVTEVLQT----QKEVEVT---RTLE
QEGSGGVELPTAICF------QG-EG---RG--RLSQKKMVTI-PSGTI-LAFR-VAQ-L
II--GSD-WDIHLFPDKKQRT------FQPPPRGHKPSGSADGW--WKPCFGF-------
-----------------------SS--T----------ESIS-HDQ---KFLA-DGPSEK
QVVTED--FQG----LQAEVGARSTELEHMEPGL-SRQLLGDLAAVL--RNKPALQA---
LEDSLEQGLCS---GWAEPLDGPAGAVLQCLLLPSGMLV--QELANSIFYLLGAL-T---
-----------------------------VLSETQHVLL-AEA------LETGALPGQLK
LVGS----LLERA--------PWQERGTVSLPLE-L----S-SSWL-E--GAPAWVLL--
-----EECGLEL--QVD-APHVRW---EPQAQGPTC-ALYASLVLLSGLSQEPQ------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FDQ
ASKDVVKKLQ-G-RDLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PMPFIHVQSMQ-LEA--NLDVQ
-----R--IVGGGVG---------YDGYGGY----------YIEVQ-RTSIPN-PKLESL
Q--N------RNLLDQWPTYMNNCLIEG--KNLYVVTEAYEV----TKDTVLE---GTSN
GKFGIKGIINQLVKV------GG-SG---QW--QTERTDSIPI-KKGSV-LAYK-KQQ-L
VI-ENNT-CVILHSANAKK-----KMTFPNRPKALSG-PTGPTLR-YQEL----------
---------V--------------------------IEIELQGSWI---NAIDPIGTIKE
-P--AHLDFMC----LQHEVSEQTQLLAKLSKDV-QEVVFSSFLHMLSDR--DVLYD---
LMKMLEL----N---QLGHMDGPGGKILDELQKDSSTPW--XDLKDLILYLLQAL-M---
-----------------------------VLSDTQLCLL-AQS------VEMRLLPHQRE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLSEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 874)

VFET
NTRIVVQELD-AGGDMIAVRSILEANRLHCFCLVRK--K-----FLGCR-Y---------
-YSTDLTLEDILERG----------------------------ESEGQ--FDKLDS-VF-
------------------------------GQ-KA---EFQVVDSVDSK-GMLTMKLPQA
-ITI------AGDF-----------HGSQEQ----------RIEIL-EPRISQ-QYLNSL
E--N------RKLKRKLPTSFQSIQTMR--EDLYLATETLET----AKKETLK-------
--SECRFAFWSQLDL---CDL---KY------ERKH-QRAVTV-PAKYV-LGYR-IKQ-L
VF-PNME-WMSIGLDIC---------------FSG-------------------------
-------------KT-----------------------------K------SFPEG--K-
SL--NLKDIRN----MKERVQDTARGLQDLTEEE-PKDALSCLTKCL--TKDEQLQD---
LEQRMSEVLISG----ELHMDSPAGPLISSLLNAAGILV--ETRTEAIMDFLDAV-M---
-----------------------------ELFE-EKELV-GEA------LEKGTLPLLKE
QAES----VLDQNGGE----QPEC--VGCDPE----------------------------
-------------------------------AQILH-ALYVAVSILLQLSEKPASASS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 795)

FDQ
ASKDVVKKLQ-G-RDLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PMPFIHVQSMQ-LEA--NLDVQ
-----R--IVGGGVG---------YDGYGGY----------YIEVQ-RTSIPN-PKLESL
Q--N------RNLLDQWPTYMNNCLIEG--KNLYVVTEAYEV----TKDTVLE---GTSN
GKFGIKGIINQLVKV------GG-SG---QW--QTERTDSIPI-KKGSV-LAYK-KQQ-L
VI-ENNT-CVILHSANAKK-----KMTFPNRPKALSG-PTGPTLR-YQEL----------
---------V--------------------------IEIELQGSWI---NAIDPIGTIKE
-P--AHLDFMC----LQHEVSEQTQLLAKLSKDV-QEVVFSSFLHMLSDR--DVLYD---
LMKMLEL----N---QLGHMDGPGGKILDELQKDSSTPW--XDLKDLILYLLQAL-M---
-----------------------------VLSDTQLCLL-AQS------VEMRLLPHQRE
LVKS----ILQPNFKP-----SLS--PGYI------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSY

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFDW
LSKDVVKKLQ-G-RDLRPVQCLSDATKFSLFNILQETS---SRLALKTE-Y---------
-IPVGFTLLHLLEPN----------------------------I---P--VPEPEVSA--
--------------------------------------PIPLKHTISQK-LKA--DLDVQ
-----T--IAGGEAG---------FVKSCGY----------DIEVQ-SKSIPN-PKLESL
Q--N------RNLLDQWPTYMNNCLIEG--KNLYVVTEAYEV----TKDTVLE---GTSN
GKFGIKGIINQLVKV------GG-SG---QW--QTERTDSIPI-KKGSV-LAYK-KQQ-L
VI-ENNT-CVILHSANAKK-----KMTFPNRPKALSG-PTGPTLR-YQEL----------
---------V--------------------------IEI---GSWI---NAIDPIGTIKE
-P--AHLDFMC----LQHEVSEQTQLLAKLSKDV-QEVVFSSFLHMLSDR--DVLYD---
LMKMLEL----N---QLGHMDGPGGKILDELQKDSSTPW--XDLKDLILYLLQAL-M---
-----------------------------VLSDTQLCLL-AQS------VEMRLLPHQRE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLSEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 795)

FDQ
ASKDVVKKLQ-G-RDLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PMPFIHVQSMQ-LEA--NLDVQ
-----R--IVGGGVG---------YDGYGGY----------YIEVQ-RTSIPN-PKLESL
Q--N------RNLLDQWPTYMNNCLIEG--KNLYVVTEAYEV----TKDTVLE---GTSN
GKFGIKGIINQLVKV------GG-SG---QW--QTERTDSIPI-KKGSV-LAYK-KQQ-L
VI-ENNT-CVILHSANAKK-----KMTFPNRPKALSG-PTGPTLR-YQEL----------
---------V--------------------------IEI---GSWI---NAIDPIGTIKE
-P--AHLDFMC----LQHEVSEQTQLLAKLSKDV-QEVVFSSFLHMLSDR--DVLYD---
LMKMLEL----N---QLGHMDGPGGKILDELQKDSSTPW--XDLKDLILYLLQAL-M---
-----------------------------VLSDTQLCLL-AQS------VEMRLLPHQRE
LVKS----ILQPNFKP-----SLS--PGYI------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MLER
ISKNLVKEIG-S-KDLTPVKYLLSATKLRQFVILRKKKD-SRSSFWEQSDY---------
-VPVEFSLNDILEPS----------------------------S---S--VLETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DMGVN
-VGIEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---DSSS
VNILGKIA-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYEISEM-VGYCAAR-SEGLLPSFHTISPT
LFNA-SSN-DM---KLKPELFLTQQ---FL-----SGH--LPKYEQ---VHILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVMFYSILAML--RDRGALQD---
LMNMLEL----D---SSGHLDGPGGAILKKLQQDSNHAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDFQHDLL-ACS------MEKRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DVEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTALDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------H------SPS-DPTD--
------------------------------------SGSFSFKNMLDAR-VEGEVDVPRT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLA-ADHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHSEAVTL-PKGCV-LAFR-VRQ-L
MV-NGRDEWDIPHLCNSDMQT------FQPGEKLGEE-----K-----------------
----------------------F---------------------TV---IQASEVR----
-E--VHEDFMA----LKEEVQRETQEVGKLSRVG-QGSLLSALSNLL--GKKKELQD---
LELELEGALDKGHKV---TLEALPKDV---------PLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MEKKILPVQLR
LVES----TLEQNFLQ-----EKE--AVYPLSPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRC-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLACSP-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PPGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLA-ADHPFLKEMRDLG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTI-PKGCV-LAFR-VRQ-L
MV-NGKDEWDIPHICNDSMQT------FPPGEKPGEEKFI--------------------
---------------------------------------------F---IQASDVG----
-E--MHEDFKT----LKEEVQRETREVEKLSQVG-QNSLLSSVSNLL--GKKKELQD---
LEQTLEGALDKGHEV---TLEALPKDV---------LLS--KDAMGAVLYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKKLLPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYMW---DPDTLPRLC-ALYAGLSFLQLLSKAC-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 802)

AFER
VVKSVIRELD-QRGELIPVDSLQSSTSFQPYCLLVRKPS--RSWFWRHR-Y---------
-KCVNLSIRDILEPN----------------------------A---P--EPAVERGG--
--------------------------------------PFHFQDTVDGQ-VKGSVELTAP
GHG-----RLGGGAS---------VSGSSSA----------SMNVC-RLQVVP-NTWVAM
Q-QE------RRLRQPEHKILQQLRNRG--VDVFVVTEVLQT----QKEVEVT---RTHK
QEGSGQFVLPGAVGL------QG-QG---QG--HLSQRKTVTI-PPGSI-LAFQ-VAQ-L
VI--GSD-WDVLLFPGKKQRT------FEPPQAGQRPSCEDRKP--PQTL----DV----
--------------------------------------SSKSVSGF---RIES-DGSTED
GLVPT-QDFQG----LQKEVRAQAEGLEGLCKDL-REQLLGGLRQVL--REELALQA---
LEEALEQGLCCG--RVEEPLHGPGHAILDCMVLTSGVLE--KDLAGPISYLLGAL-A---
-----------------------------VLNETQHVLL-AEL------LETGTLLEQFE
LVRS----LLEQS---S----PMAELQGCVPATQAP----G-EQLG-P--RGACLGP---
------AGGVRPRPAGG-RPPGVLGAAGPGLHVCTL-RLPGG------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEN
VTRALARQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEAG----------------------------S------SPA-DPTD--
------------------------------------SGNFSFKNMLDAR-VEGEVDVPKT
-------VKVTGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALETL
H-QE------RKLA-AEHPFLKEMQERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCI-LAFR-VRQ-L
MV-KGNNEWDIPHICNDNMQT------FPPGEKPEEKF----------------------
----------------------T---------------------HV---ILASDAG----
-E--EHEDFKT----LKEEVQREIQEVKKLNQAG-QNSLLTCLSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LVS--KEAMGGILYFLGAL-T---
-----------------------------ELSEAQQKLL-IKS------MEKKILPMQLK
LVEN----TMEQSFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
--------------------------------------------------------MFKK
VTQKVAKQMD-PKGELVPVHSISDQDHFRLLCLVRRKRT--ARFQPSPS-Y---------
-RRTEYSLHDVLLPA----------------------------E---E--RDSVESLLP-
------------------------------STDSHSPREFTTTGSTKDR-VDGTLSIPID
-R---AEVELGGAA-----------STAKQW----------HVKLE-KKHILV-PKLEAL
R-EK------RKIN-MKHTFIEQLRKVR--QNLYVIHETIET----SEEARYE---ESTE
AEAKFMAQLY--A------KFSA-KG-------TTGSKQSITI-PRGCT-LAFR-AMQ-L
SI-GDAA-WGVNHFPENNQP------TFASDGF---------------------------
---------AH----------------------------------------

PF04598 // ENSGT00530000063218_Domain_1 (592, 863)

-TEVE----
--------------ALEEEVKERCGILCQLTDEL-NAVVVKTIKAVM--RDRNLLEE---
LSGKMEAVLDDPDNCELTTQSPDLEVLLSTLKGSPRCDL--LSLTEAISYTLDAF-S---
-----------------------------ELTEDQLLLL-LES------LEVEIVPQQLK
LVRS----ILEQSAEL-----GA---A-AGL---LS----SFSEQQ-Q--QQLTTAVL--
-----QLSGVEL--QGS-GAAVCT----EESFPSLS-ALYAALHALHCLVGAGGRPARAD
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_2 (117, 158)

LFEP
ISKNLVKELG-D-KDLRPVKYLLSTNKFRQLALLWKKKG-----THAQS-W---------
-GQPTVPVEYLTDIE----------------------------PSSSV--PXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX---XXXXXXXXXXX-XXXXXXXXXX
-XXXXX---XXXXX-----------XXXXXX----------XXXXX-XXXXXXXXXXXXX
X--X------XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXX----XXXXXXX-------
--XXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXX-XXXXX-XXXX-XXXXX
XX-XXXX-XXXXXXXXX---------------XXXXX--------------X--------
XXXXXXXXXXXXXXX-----XILPM---------------G

PF04598 // ENSGT00530000063218_Domain_1 (582, 868)

IRE----------------
-P--TGQGFKH----LQKEVCREMEAMAQLPKDT-QDAILHNILARL--KDREALQD---
LMDLLDR---GP----SDHLDSFGGTFLSEMQEDSRNLW--LKLRLHIISLLKAI-L---
-----------------------------GLSDTQHELL-AWS------IEKRILLQQRA
LVKS----ILEPNFKY-----PWN--IPFTLAPKLL----T-PLQVEG--LAVTFSLL--
-----EECSLRV--APD-SPKG-T---DLEAKKPLF-TLYGSLSVPQQLAKA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSI

PF04598 // ENSGT00530000063218_Domain_2 (118, 165)

FEE
ITRIVVKEMD-AGGDMIAVRSLIDADRFHCFHLVEEKRT-----

ENSGT00530000063218_Linker_2_1 (165, 384)

VFGYG-----------
--DK-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDSK-GKLI------
--------------------------V---------------------------------
---K------LKLKRELPFSFRS

PF04598 // ENSGT00530000063218_Domain_1 (384, 795)

INRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNEIFQ---SHL---SY------EYKG-QREVTI-LPNRV-LSYR-VKQ-T
GL-SNNL-FFPSLFGAC-------------------------------------------
------FDICLRDKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--GSEDSRN----MKEKLENMESVLQELTEDK-RKDVLNFLTKCL--GREELWQD---
LEQKISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--GARAEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHD--MDCDPE----------------------------
-------------------------------ARIPC-ALYVVVSVLLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-LRTDYTLLDVLEPG----------------------------S------CPS-NPTD--
------------------------------------SGNFAFKNMLDAR-VEGQVDVPRT
-------VKVTGTA-----------GLSRSS----------TLEVQ-TLSVAP-KALEAL
H-QE------RKLE-AEHPFLKEMRDRG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GVFSLPFFAPLGL------------QG--SINHKEAVTI-PKGCI-LAFR-VRQ-L
MV-KGENEWEIPHICNDNMQT------LPSWRKPEEEKLI--L-----------------
----------------------I---------------------Q----ASDVGKG----
-E--MHEDFKT----LKEEIQRETQEVEKLSHVG-QSSLLTALSKLL--GKKKELQD---
LELTLEGALDKGHEV---TLEALPKDV---------LIS--KEVMGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-VKS------MEKKILPVQLK
LVES----TMEQNFLQ-----DKE--GVFPLQSNLL----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPHLC-ALYAGLSFLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSI

PF04598 // ENSGT00530000063218_Domain_2 (118, 165)

FEE
ITRIVVKEMD-AGGDMIAVRSLIDADRFHCFHLVEEKRT-----

ENSGT00530000063218_Linker_2_1 (165, 285)

VFGYG-----------
--DK-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILD

PF04598 // ENSGT00530000063218_Domain_1 (285, 795)

NVDSK-GKLI------
--------------------------GSHDQ----------KIEIS-ENWISQ-QYLDTL
E--N------RKLKRELPFSFRSINRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNEIFQ---SHL---SY------EHKG-QREVTI-LPNRV-LSYR-VKQ-T
GL-SNNL-FFPSLFGAC-------------------------------------------
------FDICLRDKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--GSEDSRN----MKEKLENMESVLQELTEDK-RKDVLNFLTKCL--GREELWQD---
LKQKISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--GARAEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHD--MDCDPE----------------------------
-------------------------------AQIPC-ALYVVVSVLLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEY
VSKKMVKNIG-G-KDLRPVKCLLDATKFRQLNVLRKN---SQSRFWEQPDD---------
-NPVGFSLMDILEPS----------------------------S---S--APGHLATA--
---------------------------------------------------LI--GGDIS
-AGVEG--SVSGNF------------------------------IQ-AVSIPD-PKLETL
Q--N------RKLLHPEPSFLTECRMRG--DNLYVVTEAIEL----TKDTVLQ---EGSR
VETLGKLAA-------------------NFS--LKARETKLSV-PQGTV-LAYR-KKQ-L
VI-RKQG-SGEQEGAG----------KWGGGLQAVTF-AVPCPRR-GRAALLTV-PGSPP
SMAS-----------LKSRWLS-------------CGR--SLLGGK---NLGRSTGRIEE
-P--LHQDFQL----LQEEVSCNTALLAQLSKDV-QAVIFHSILSLL--GDREALCG---
LTNMLEL----D---RLGQMEGPGGIILDELCQGTRPPW--IDLKSLILYLLQAL-M---
-----------------------------VLSDTHLDML-ALS------MEKGILLHQRE
LVRS----ILQPNFKY-----PWC--IPLTLQPQLL----A-PLQAEG--LAITYGLL--
-----EECGLKM--ELN-NYKPSW---DLEAKMPMS-ALYGALSLLQQLTLPGGQ-----
-----------------------------------------------

------------------------------------MISAHCNLRLPGSSDSP-------
---------------------AS-ASRILPGRPDAPLGPPTGTMPHPFSLLRSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-HSGELIPMTSPKDSPGFQPYFLVVRKPS--SSWFWKPC-Y---------
-KPLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRGGVELSAP
GQA-----KIAGGAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLQQPEHKILQQLRSRG--DNVYVVTEVLQT----QKEVEVT---QTHK
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLH----------
--------------------------SV----------LSMMGCLH---NFSA-DGVPAE
GTFTED--FQG----LRAEVEAISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGPSL---GPVEPLDGPAGAVLECLVLESRMLV--PELAVPVVYLLGAL-T---
-----------------------------MLSETQHELL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTVSLPPGLL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSNI

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FER
ASKNMIKRLG-G-KDMRPVTCALDANKFRQFSIILKR---SRFLIGEGPDD---------
-IPVGYSLMQILEPS----------------------------S---S--VPDSVISG--
--------------------------------------PLSTVDFEVKK-LTA--DVGIN
-VGVEV--SVSGGV-----------TRSHGS----------TLEIQ-SVSIPN-CNLEIL
Q--N------RKLLDQEPSFLSICRRRG--DNLYVVTEAVEL----TKDTVLC---DNSS
VALSGKVSIPQVTSV------KG-EGQ-GQG--Q--RETTMRV-LQGTV-MAYR-KKK-L
VI-KDKY-CSVLVIDDTK------QRTFQYEQPTLRS-AEMTKHH----F-----QCSPR
------SI-CV---E-------APE---EL-----RRE--IYKMEF---SPILPIGRIEE
-P--FGKGFRL----LEEEVSENVKALAWVSKDG-RDVMFHSILAML--ADREALQK---
LMDMLEM----E---NFSHLDGPGGKILDELRQGSSPPW--INLENLIFYLLEVL-L---
-----------------------------VLSDAQFVLL-VQS------VEKRILFQQRE
LVRS----ILEPNFKY-----PWH--IPFTLPAELL----S-PLQGEG--LRITYALL--
-----EGCGLEM--ELG-SPRSTW---HLEAKMPLS-ALYAALSLLLQLAKDWQRVSPGP
GPAHSVRTLGRPGRSRCSHFLPGTLIHVETGVGRDLRECSRVMEMLR

------------------------------------------------------------
-----------------------------------------------------MAPVFRD
TTQALVRQLD-PTGELIPLGSIIDVSRFRPFCLVRRKRKG--TLFWGAQ-Y---------
-VKTDLSLRDVLEAG----------------------------T---K--LPGRV-----
---------------------------------------IHYYNNPPSR-A-----C---
-TH---TCIPSRIR-----------NTALEA----------TVHVK-DPEA

PF04598 // ENSGT00530000063218_Domain_1 (352, 864)

NK-NH-NS-
F-SS------RKLKKPEPSFLKKLRERG--ENLYMVTEAVET----LKDAKLE---KGRK
--GGAGISIPLLTAM----GLKV-GGS--FS-----FNTTIHV-SLGSV-LAFR-LKQ-L
VI-GEKN-WGMFQDWTT-------------RCVRKA----------------PVSMNARG
NVGLQDPGPSHCVSK-----A--GQ---------------WPESSS--------------
-K--EHRGFKA----LQAEVEAEISILKNLTLER-REILLDALLGLL--GQSKALQE---
LEDMMNRALDLEEPVIQGFLGGPGDTILAKLQDISGKLN--PSWAGSILYLLGAL-Q---
-----------------------------ELSEEQQQLL-AMA------VEKRILFQQLE
LMET----ILDQNFLR-----AEA--GPFRLHCELL----Q-SFQGEE--LTVTQALI--
-----GLCGLDL--QGD-GPLFAW---DPDALPPLC-ALYAALSVFQGLSRIPW------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------EDFGA----LQ

PF04598 // ENSGT00530000063218_Domain_1 (618, 864)

-RVESEARQLAQLTPEA-RATLLRSLRALL--GKNHQLRL---
LEGSLEGALHKGTPG---TLEDLG-NV---------TLS--PQAMGSILYFLGAL-T---
-----------------------------ELSEAQQKLL-AQS------MEKKILLTQLK
LVER----AMEENFQQ-----SQG--GDFPLPPQLL----S-SLGDED--LTLTEALV--
-----GLIGLEL--HRA-GPFYFW---EPATLPRLC-ALFTGLS----------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEK
VVKNVIKEVSGSRGDLIPVDSLRNSTSFRPYCLLNRKFS--SSRFWKPR-Y---------
-SCVNLSIKDILEPS----------------------------A---P--EPEPECFG--
--------------------------------------SFKVSDVVDGN-VQGRVMLSGM
GEG-----KISGGAA---------VSDSSSA----------SMNVC-ILRVTQ-KTWETM
Q-HE------RHLQQPENKILQQLRSRG--DDLFVVTEVLQT----KEEVQIT---EVHS
QEGSGQFTLPGALCL------KG-EG---KG--HQSRKKMVTI-PAGSI-LAFR-VAQ-L
LI--GSK-WDILLISDEKQRT------FE-PSSGDRKAVGQRHH--GLNVLA--------
--------------------------AL----------CSI-GKQL---SLLS-DGIDEE
ELIE-AADFQG----LYAEVKACSSELESLEMAL-RQQLLVNIGKIL--QDQPSMEA---
LEASLGQGLCSG--GQVEPLDGPAGCILECLVLDSGELV--SELAAPIFYLLGAL-A---
-----------------------------VLSETQQQLL-AKA------LETTVLSKQLE
LVKH----VLEQS---T----PWQEQSSVSLPTVLL----G-DCWD-E--KNPNWVLL--
-----EECGLRL--QVE-SPQVHW---ELTSLIPTS-ALYASLFLLSSLGQKPC------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------FDPPWFLKQCRER---ESLYVVTEAVEV----TNSPVLH---SSKS
VKGLGKV--PWDPLA------KV-QGQ-VEC--LNMGKETLVL-PQGTV-MAYQ-RKK-L
II-KKDX-XXXXXXXXXXXXX---XXXXXXXXXXXXX-XXXXXXX-XXXX-----XXXXX
X-----XX-------XXXXXXXXXX-XIFL-----SFGFLFGFLLW---CFQVYIGGKEE
-A--FGNNFQC----LQKEVAREMETLAQLSKDV-QGVIFNDILAVR---GSEALQD---
LMDKLEE----Y---PVGNLDGPGRDILNEIQKAASHGR--SNLNVCILYILGAM-M---
-----------------------------XXXXXXXXXX-XXX------XXXXXXXXXXX
X

PF04598 // ENSGT00530000063218_Domain_1 (782, 864)

VRS----ILEPNFNH-----ADS--VSFAFRPELL----A-AVQGES--LTITYGLL--
-----EECGLDI--EPN-SPRSVW---VPEAKESLC-ALYGCLSILQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRRVVQELD-HGGEFIPVTSLQSSTGFQPYCLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------A---A--EPDVQRGR--
--------------------------------------SFHFYDAMDGQ-IQGSVELAAP
GQA-----KIAGGAA---------VSDSSST----------SMNVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKVLQQLRSRG--DNVYVVTEVLQT----QKEVEVT---RTHK
REGSGRFSLPGATCL------QG-EG---QG--HLSQKKTVTI-PSGST-LAFR-VAQ-L
VI--DSD-LDVLLFPDKKQRT------FQPPATGHKRSTSEGAW--PQLP----------
--------------------------SG----------LSMMRCLH---NFLT-DGVPAE
GAFTED--FQG----LRAEVETISKELELLDREL-CQLLLEGLEGVL--RDQLALRA---
LEEALEQGQSL---GPVEPLDGPAGAVLECLVLSSGMLV--PELAIPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTMSLPPGLL----G-NSWG-E--GAPAWVLL--
-----DECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----DIGI-------------------------------------------TG

PF04598 // ENSGT00530000063218_Domain_1 (234, 855)

MI-----
----------------------------------------TFSA----------------
-------------------------GGSHNN----------YLEIQ-KLSVVH-EL-ES-
L-RK------RKLKVPEPNILKKLREHN--ENLYMVTEAVET----LKDAKLE---KRRK
--ADAGIYVPLLNAL------QF-KGS--FS-----FDSTIHV-SEGSI-LAFR-VKR-L
HF-FHRD-WGMFQRREG-------------SK----------------------------
RAFVWGPGANHSVSK-----VMWQQ---------------EPEKPS--------------
-Q--RTTRFQA----LQAEVKPQIHILETLTQKH-RKSLMEALLGLL--GQAKALQE---
LEDTMNRALDLEEPGTPGFLGGPGDAILAKLQDASGKLN--PSWAGSILYLLGAL-H---
-----------------------------ELSEEQQQLL-AMS------VEKEILSQQLE
LMKT----ILDENFLR-----TEA--GSFPLHCELL----Q-SLQGEE--LTVTQALI--
-----GLCGLDL--Q---------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRK-KD-SRSSIWGQSDY---------
-VPVGFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIMIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSG
VNILGNIS-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LVSCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLNDIQHDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPG

PF04598 // ENSGT00530000063218_Domain_1 (117, 796)

LFEE
ITRATVRELG-FGGNMIAVRNAIDADRFHCFCLVREKRS-----FLGLQ-Y---------
-CKTDLTLKDILEE-----------------------------ESERP--NDELESETP-
------------------------------GQ--C---EMGSLEMVTEG-WSLIEKLPRA
-ITIKG---MSGEF-----------QGTQKQ----------GIKIL-LNRISQ-QHLLSL
E--N------RKLKRKLPSSFQSIQAKR--EGLYLVTETLET----KNEETLR-------
--SDRRYKFFNW------RCL---EF------EHQH-KKEVTI-PPKWV-LGFR-IKQ-L
VF-PNQE-R---------------------------------------------------
------MSICFSGKT-----KSFLE---------------EKDGG------SSLLG--K-
SL--NLEDVRS----MKEQVQDMGRGLQDLTEEE-RKDVLSCLTNFL--SKDGQLQD---
LEQRVSEVLSSG----ELQIEGPASPLISSLFNAVGILE--EARAEAILALLDAL-T---
-----------------------------ELSKEEQQLV-AEA------LEKGILPQLLD
QVET----ILEQNLDEQ-LGSPSD--KDCDPE----------------------------
-------------------------------EQSIC-ALYVALSILLQLAKGPTSAPS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

SFSG
VVRSVVRELD-RTGELIPVDSLRSSTSFQPYCLVSRKPS--TSWFWRSR-Y---------
-TSVNLSIRDILDPN----------------------------A---P--EPGVQCRG--
--------------------------------------PFHFHDTMDGR-VQGSVELAAP
GQG-----RIKGGAT---------VSGSSSA----------SMDVF-TLRVDP-STWETL
H-KE------RRLRQPEHKILQQLRNRG--DNVYVVTEALQT----QKEVEVT---RTHK
QEGSGQFALPGVTCL------QG-EG---QG--HLSRKKTVTI-PSGSI-LAFQ-VAK-L
VI--GPD-WDILLLPDKKQRT------FQKPPAGEAMTCPQPAV--HGRSLP--------
--------------------------LL----------MDSIQQPI---RFLS-DGPTEE
RAV-VTKDFAG----LRAEVEPQAQELENLSKEL-RQEMLGALGRLL--LDTPALQD---
LEEALEQGLCC---GRVEPRDGPVGTVLECLVLPSQELV--KDLAIPVFYLLGAL-T---
-----------------------------ALSETQHLLV-AQA------LETRALPRQLE
LVGS----VLKQS---S----PWQEPRAVSLPPGLL----G-SSWG-E--DAPAWVLL--
-----EECGLEL--QVG-PPQACW---DPEAQGHTC-ALYAALALLLRLGQEPC------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFES
VVRSVVRELD-PRRELILVDSLQNSTSFRPYYLLRRKPS--SSRFWKPR-Y---------
-SCVNLSIKDILEPD----------------------------A---P--EPDLEHGS--
--------------------------------------TFHFNDTIDGK-VQGNMEVAVP
GQW-----KISGGAA---------VSGSSST----------SMNVR-TLSVDP-NTWDRM
Q-QE------RRLRQPEHKILQQLRSRR--DDVFVVTKVLQT----QEKVEVT---RMRK
QEGAGHCVLPGAMCL------KG-DG---EG--HLRRENKVTI-PAGSI-LAFQ-VAQ-L
VI--RSD-WDIFPFPDEKRRT------FLPSPTDSQPQNT----------FSL-------
-----------------------S--SV----------LRAIRDSL---KLLT-DGISEE
SVVTEE--FQV----LRTEVEAGFAALKKMARDL-RQQLLLNLRKVL--CDPPALQD---
LEVLLAQGLCGA--KQVKPLQGPAGNILECLVLPSRVLV--PTLAAPVFYLLGAL-T---
-----------------------------ALSETQQQLL-AQL------LDKGDLSTLLE
LVEH----LLEQS---I----PWQEQSDVSLPPKLL----A-SNWG-E--EAPAWALL--
-----EKCGLEL--QVG-APQIHW---EPQAQGPTC-ALYASLALLSGLS----------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPST

PF04598 // ENSGT00530000063218_Domain_1 (118, 371)

FEC
ATKNLVKELS-KNGELIPVESLKSSTHFSPYYLVRRKTK--SSWFWRPQ-Y---------
-VWLNLTLKDILDPS----------------------------S---P--EPEVIQNG--
--------------------------------------PFHFNDEEDGK-VSGSVEVTAS
MQS-----KISGQTS---------VSN--RT----------DLEVK-TLMVPL-HTWDCL
Q-KE------R-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTALDSLIDFQRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDVLEPG----------------------------S------SPA-DPTD--
------------------------------------AGSFSFKNMLDAR-VEGEVDVPRT
-------VKVKGTA-----------GLSQNS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLA-EDHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SVNHKEAVTL-PKGCV-LAFR-VRQ-L
MV-NGRDEWDIPHLCNDGMQT------FPPGEKPGEE-----K-----------------
----------------------F---------------------TL---IQASDVG----
-E--VHEDFKT----LKEEVQRETQEVDKLSRVG-QGSLLSSLRNLL--GKKKELQD---
LELALEGALDKGHEV---TLEALPKDV---------PLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MEKKILPVQLK
LVES----TLEQNFLQ-----EKE--GVFPLRPELL----S-SLGDEE--LTLTEALV--
-----GLSGLEV--QRG-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLARSP-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGYS

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FDR
ASKDVVKKLQ-G-RDLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PKPFIHVQSTD-LEA--NLNVA
-----D--IARGGVG---------YVGYGGY----------NIEVQ-STSIPN-PKLEIL
Q--N------RKLLDKLPTFMKFCRMER--KNLYVVTEAYEV----SKDTMLT---GLSS
VNLLVKGFFKQLFKV------RG-KA---GR----SEKYSIPI-PKGSV-LAYK-KQQ-L
VI-ENNT-CVILPSAT-KK-----KMTFPDRPLKLYD-L-PVTLR-YQEE----------
--------------------------------------VIETGSWI---DDIDPIGTIEE
-P--ANLNFMC----LQHEVSEQTQLLAELSKDV-QEVVFSSFLHML--SDRDVLYD---
LMKMLEL----N---QLGHMDGPGGKILDELRKDSSTPH--DVLKDLNLYLLQAL-L---
-----------------------------VLSDTQLCLL-AQS------VKMGLLPHQVE
LVKS----ILQTNFKY-----SSN--TPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLQKANSSSKPSL
SPGYI------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRGLARQLN-PRGDLTPLDSLIDFQRFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDLLQPG----------------------------T------SPS-XXXX--
------------------------------------XXXXXXXXXXXXX-XXXXVDVPKT
-------VKVKGTA-----------GLSHSS----------MLEVQ-SLSVSP-KALDDL
--KE------RKLV-PEHSFLKEIKERG--ENLYVVMEVVET----VKEITLE---NAGK
AS--GCLSLPFFAPLGL------------QG--SVDHKEAITI-PKGCV-LAFR-VRQ-L
VI-KGKDDWDIPHVSNESLKT------FPTEEKPEEKI----------------------
--------------------------------------------FS---LLVFCIA----
-E--VPEDFGS----LKKEVQSEVHQVDKLSREG-QASLLKSLRSLL--GKKQDLQD---
LELSFEEALNKGHPV---SLEASPKDI---------ELS--RDVVEGILYFLGAL-T---
-----------------------------ELTEAQHKLL-AKS------MEMKILPLQLT
LVES----VMEQNFSR-----TEE--GLFPLKPELL----S-SLGDEE--LTFTEALV--
-----GLSGLVM--QR--SFKYNW---DPDTLPQLC-ALYASLSFIQLLT----------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MSMFED
VTRALTRQLN-PSGDLTPLDSLIDFKRFRLFCLVLRKRK--STLFWGAR-Y---------
-VRTNYTLLDVLEPG----------------------------S------SLS-DPTL--
------------------------------------LGNFSFKNMLDAR-----------
-----------------------------------------------TLSVAP-TALENL
H-KE------RKLS-ADHPFLQEMREYK--QNLYVVMEVVKA----KQEVTLK---RASN
AI--SKFSLN-LPSLGL------------QG--SVYEKDEVTI-PKGCV-LAYR-VRQ-L
IV-YGED

PF04598 // ENSGT00530000063218_Domain_1 (488, 864)

KWG--------------------------------------------------
------------------------------------------------------------
-E--MHEDFKT----LKKEVQRETQEVEKLSPVG-RNSLLTSLSHLL--GKKKELQD---
LEQKLERALDKGQEV---TLEALPKDV---------MLS--KDIMDAILYFLGAL-T---
-----------------------------ELSEEQQKIL-VKS------LENKVLLVQLK
LVEN----ILEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---NPDTRHNLC-ALYAGLSLLQLLSKNS-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALTRQLN-PRGDLTALDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------H------SPS-DPTD--
------------------------------------SGSFSFKNMLDAR-VEGEVDVPRT
-------VKVKGTA-----------GLSRNS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLA-ADHPFLKEMRERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QV--RFPRI---------PK-LQQR-VRS-L
S----LGDGNIPHLCNSDMQT------FQPGGKRKPLL----A-----------------
----------------------A---------------------WI---IQASEVR----
-E--VHEDFTA----LKEEVQRETQEVGKLSRVG-QGSLLSALSNLL--GKKKELQD---
LELELEGALDKGHKV---TLEALPKDV---------PLS--KESMGAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------MEKKILPVQLR
LVES----TLEQNFLQ-----EKE--AVYPLSPELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRC-GPQYTW---DPDTLPRLC-ALYAGLSLLQLLACSP-------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MTMFEN
VTRALARQLN-PRGDLIPLDSLIDFKHFRPFCLVLRKRK--STLFWGAR-Y---------
-VRTNHTLLDLLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFSFKNMLDVH-VDGDVEVPKA
-------LKVKGTA-----------GLSQSS----------TLEVQ-TLSVAP-SALENL
K-KE------RKLS-ADHSFLKEMRNHE--KNLYVVMEAVEA----KQEVTLE---QTVN
AN--AIFSLPSFALLGL------------QS--MALA--------KGSK-V---------
---F---------------------------------VMTDVVF----V-----------
------------------------F-----------------SEKP---EEE

PF04598 // ENSGT00530000063218_Domain_1 (593, 864)

KLIG----
-E--MHEDFKT----LKEEVQRETQELEKLSPVG-RSSLLTSLSHLL--GKKKELQD---
LEQKLEGALDKGQEM---TLEALPKDV---------LLS--KNAMDAILYFLGAL-T---
-----------------------------ELSEEQQKLL-VKS------LEKKILPVQLK
LVEN----ILEQNFLQ-----DKE--GVFPLQPDLL----S-SLGEEE--LILTEALV--
-----GLSGLEV--QRS-GPQYTW---NPDTRHNLC-ALYAGLSLLHLLSRES-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRK-KD-SRSSIWGQSDY---------
-VPVGFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDIVIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSG
VNILGKIS-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LVSCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---KLKPELFLKPK---FL-----RGH--LPNDDL-----ILLLGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNRAW--FNPKDPILYLLEAI-M---
-----------------------------VLNDIQHDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-NPRSTW---DLEAKIPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSI

PF04598 // ENSGT00530000063218_Domain_2 (118, 165)

FEE
ITRIVVKEMD-AGGDMIAVRSLIDADRSHCFHLVEEKRT-----

ENSGT00530000063218_Linker_2_1 (165, 285)

VFGYG-----------
--DK-------------------------------------------R--LDELDSGLQ-
------------------------------GQ-KA---EFQILD

PF04598 // ENSGT00530000063218_Domain_1 (285, 795)

NVDSK-GKLI------
--------------------------GSHDQ----------KIEIS-ENWISQ-QYLHTL
E--N------RKLKRELPFSFRSINRRE--N-LCLVTETLEM----VKKETLK-------
--SDRQYKFGNEIFQ---SHL---SY------EHKG-QREVTI-LPNRV-LSYR-VKQ-T
GL-SNNL-FFPSLFGAC-------------------------------------------
------FDICLRDKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--GSEDSRN----MKEKLENMESVLQELMEDK-RKDVLNFLTKCL--GREELWQD---
LEQKISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--GARTEAILDFLDAL-L---
-----------------------------ELSE-EQHLV-AEA------LEKGTLPLLKD
QVKP----IMEQNWDEL-ASSPHA--MDCDAE----------------------------
-------------------------------ARIPC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSSL

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FAR
GSQLVVRELG-RMGELVPADSLNSAPRLRPFCVLRKKCRC-HPWPWGTR-L---------
-IPTDFSLLDLLEPG----------------------------S---P--APEVSRS---
-------------------------------------QPIHIRKSVTRG-VTGAVSV---
--GLQG--KVAGGG-----------VVTHSC----------TLAVQ-TLSISP-HTWEGL
M-ES------RKLRTPRPLLLRELQSRTQRERLYVVTEAVET----LQDTTLR-S-LGRA
E-GTGQLSF-----PGLG-HLKV-QG---QST-MDRE-KTVTV-PQGSV-VAYR-VLQ-L
VV-EEDH-WGAPSLCSCS------------------------------------------
---------LPPRRA-----ALWGR---------------WWRVRG----SETGCGE---
E-----QDFQD----LRSQVAAQLQDLATLSPEL-RKTLLGALHELL--GDPQALQE---
LEDTLEQALDAG--L-LGQLQGPGGVIVCSLQDPSGNLS--PSRGRAFLHLLGAL-V---
-----------------------------VLSDSQQWLL-AQV------LERQILPQQLE
LVAS----ILEANFTQ-----REE--ARCSLPPEVL----S-ALPSEA--VVLALSLL--
-----ESCGLEL--QGP-GCQLSW---DPAAVPQVS-ALYGCLEGLQLLAGPSPGPSQPV
SEEEVTSCL--------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------

PF04598 // ENSGT00530000063218_Domain_1 (608, 864)

DFEH----LHEEIFQEVEALAQLSKDA-QDAIFHNILNML--GNQEALQD---
LMDELGG----N---PWDSLDGFGGKILNEMQEDIRDVW--IQERFHMIYLLEAI-M---
-----------------------------VLSNTQHDLL-TQS------MKKRTLLQQRE
LVKS----ILEPNFKC-----SGN--IPFTLKPELL----A-PLQDED--LAITYGLL--
-----QECGLNM--ELN-SPRLTW---DLEAKQPLS-ALYGTLSVLQQLAVS--------
-----------------------------------------------

------------------------------------------------------------
-------------------------------------------MPGPFLLLRNMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFEW
VVRRVVQELD-HGEDLIPVTSLQSSTGFKPYCLVVRKSS--SSWFWKPR-Y---------
-KHVSLSIKDILEPD----------------------------A---P--EPDLQHGG--
--------------------------------------SFHIRDTVDGQ-LRANVEVAAP
GQG-----KVAGGAS---------VSDSSST----------SLNVF-SLSVGP-NTWQAL
L-QE------RHLRRPEHGILQQLRQRG--DNVYVVTEVLQT----QKEVEVT---RTHR
REGSGLVSLAGAMCL------QG-EG---EG--HLSQKKTVTI-PSGSV-LAFR-VAL-L
VI--RSN-LEVILFPDKKQKT------FQPPPTDHRPFSNQGSR--R-------------
--------------------------VA----------LSVKGYIG---SLWT-DGVPAN
GTVTED--FQG----LRAEVEAVSKELALMDGQL-CQLLLEGLEGVL--RDQLALQA---
LEEALEQGLSS---GPVEPLGGSAGAILDCLTFPSGMLV--PELAVPVVYLLGAL-N---
-----------------------------ALSEAQHRLL-VEA------VTLKTLPRQLE
LVGS----LLEKS---A----PWQKCSTVSLPPELR----K-SGWG-G--ETPAWVLL--
-----EECGLEL--RED-PPHVRW---EPQAQGRAC-ALYASLTLLSGLSREPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFEN
VVRRVIRELD-RSRELILVNSLQNSTSFRPYSLLRRKPP--TSWFWKPR-Y---------
-SCVNLSIKDILEPD----------------------------A---P--EPGIQT----
-------------------------------------------------------HVEVP
GQG-----RISGGAT---------VSGSSIT----------SVNVC-SLSVGP-NTWDHM
H-KE------RRLRQPEPKILQQLRSCR--DDVYVVTEVLQT----QEEVEVI---RTRK
QEGSGQCAVPVAMCL------KG-EG---EG--HLSREKKVTI-PKGSI-LAFR-VAQ-L
VI--DSD-WDIFLFPDEKRRT------FPPPPPGEA------------------------
--------------------------------------------------ICA-DGVDED
WEVTED--FQG----LQTEVKAASSALQKLEREL-RQELLLNLGKVL--CDPSALQD---
LEALLAQGLFGA--RQVKIPQGPAGDILECLVLPSGVLV--QALAAPIFYLLGAL-S---
-----------------------------ALSETQQQLL-AKV------LDKGDLSTQLE
LVGH----LLKQS---T----PWQEQSDVSLPPKLL----E-SNWG-E--EAPIWTLL--
-----EECGLEL--QAG-APQVHW---EPEAQGPTC-ALYSC------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSTP

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FAR
VCKDVAKQL----DDLCPVKSLSKANKFQPFAILQTTS---HPWFWKSED----------
-IPVGYSLRQILEPT----------------------------F---P--FPEPEVSP--
--------------------------------------PMPFIFIGYQN-LKG--GLDIN
-DTFEG--SVSAGI-----------GDSRVC----------AIEVQ-CTSIPA-SKLEIL
Q--N------RKLVAKDSSFMRHCLVGN--KDLYVVTEAYEV----TKDTMVK---DRSS
VNLKGKWFLRLIAKV------WD-KDQ-------TNKVRSVPI-PKGTV-VAYK-KEK-L
VI-ENDT-CVILLSAKATKE------TFQGMYCMQHR-F---------------------
-----------------------------------PR-----RCQS---CH--PRPYALE
-S--KITDFQH----LQNEISEKTWKLARLSKDV-QEVVFSSLLPML--RDREILYD---
LMIMLEM----G---ELGHMDGPGGVILDELRK---DPW--TGLKDLVLYLLHAL-L---
-----------------------------VLSDTQLNLL-AQS------VEKRFLLKQKE
LVKS----ILQQNFKY-----PWN--IPFTLQPELL----A-PLQGEG--LAITYELL--
-----KECGLKM--ELN-NPRSTW---DLEAKMPTA-ALYGSLSCLQQLVEPKSSSDPGY
I----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 784)

AFEW
VVRRVVQELD-HSGELIPMTSPKDSPGFQPYFLVVRKPS--SSWFWKPC-Y---------
-KRLNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRAGVELSAP
GQA-----KIAGGAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKILQQLRSRG--DNVYVVTEVLQT----QKEVEVT---RTQK
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SV----------LSMMGCLH---NLSA-DGVPAE
ETFTED--FQG----LRAEVEAISKELELLDRAL-CQLLLEGLEGVL--RDQLALRT---
LEEALEQGPSL---GPVESLDGPAGAVLECLVLESRMLV--PELVVPVVYLLGAL-T---
-----------------------------MLSETQHELL-AEA------LESQTLLGPLE
LVRG----FGLQEDGLS----QWKGHCCT-------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALVRQLN-PRGDLTPLDSLIDFKRFHPFCLVLRKRK--STLFWGAR-Y---------
-VHTDYTLLDVLEPG----------------------------S------SPS-DPTD--
------------------------------------SGNFGFKNMLDAR-VEGEVDVPKT
-------VKVKGTA-----------NLSQNS----------TLEVQ-TLSVAP-TALESL
H-QE------RKLM-VDHPFLKEMRSER--MNLYVVMEVVET----VQEVTLE---RASK
AD--GCFSLPIFAPLGL------------QX--XXXXXXXXXX-XXXXX-XXXX-XXX-X
XX-XXXXXXXIPCIYNDDMRT------FPLGEKPEEEKFT--R-----------------
----------------------L---------------------M------TVPTG----
-E--ALQGFRT----LKEEVQRKTHEVEKLSPVG-KSSLLCSLSKLL--GKKKELED---
LEFTLEGALDRGHEV---TLEALPKDV---------LLS--KEATGAILYFLGAL-T---
-----------------------------ELSEAQQKLL-AIS------MEKKILPVQLK
LVES----TMEQNFLL-----DNE--GVFPLQSELL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPLYMW---DPDTLPHLC-ALYAGLTFLQLLTKAS-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFHCFHLVGEKRI-----FSGCR-H---------
-YTT-------------------------------------------R--LDELDSGLQ-
------------------------------GQYKT---EFQILDNVDSK-GKLIVKLPKK
-ITI------SGSF-----------QGSHDQ----------KIEIS-ENRISQ-QYLDTL
E--N------RKLKRELPFSFRSINRRE--N-LYLVTETLEM----VKKETLK-------
--SDRQYKFGNQIFQ---SHL---SY------EHKV-RI-----LGGRN-CEGQ-RW---
----------PA------------------------------------------------
------------------------------------------FST------AA

PF04598 // ENSGT00530000063218_Domain_1 (594, 795)

STA--K-
SL--GSEDSRN----MKEKLENMESVLQELTEDK-RKDVLNFLTKCL--GREELRQD---
LEQRISEVLIFG----ELQMEDPVNPLLSSLFNAAGILV--EVHAEAILDFLDAL-L---
-----------------------------ELSE-EQQLV-AEA------LEKGTFPLLKD
QVKP----IVEQNWDEL-VSSPHD--MDYDPE----------------------------
-------------------------------ARIPC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
---------------------------------------------------GTMSSI

PF04598 // ENSGT00530000063218_Domain_3 (118, 224)

FEE
ITRVVVQEMD-TGGDMIAIRSILHVDRFHCCSLVRGRRN-----FWGHQ-Y---------
-HRTDLILEDTLERG----------------------------EGEEL--FEKLDSG---
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 489)

VFQD
TTQALVRQLD-PSGELIPVTSIIDVSCFRPFCLVKRTR----TSFWGVR-Y---------
-VKTDFSLRDILEDG----------------------------P---E--LPEPCKG---
-------------------------------------PVIKVGENTEKT-MATAGTA---
-TDFGIPVMITFSA-----------GGSHNN----------YLEIQ-KLSIVQ-EL-ES-
L-RK------RKLKVPEPNFLKKLREHN--ENLYMVTEAVET----LKDAKLE---KRRK
--ADAGIYVPLLTAL----G--F-KGS--FS-----FDSTIHV-SEGSI-LAFR-VKR-L
HF-FHRD-WATLEQDEDFRGYF---DMPYSKCCHGA----------------PLPKYSP-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------

PF04598 // ENSGT00530000063218_Domain_1 (372, 864)

RLRQHEPKILQQ-HSRG--DDVYVVTEVLQT----QREVEVT---RSQK
REGSGRFALPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGST-FAFR-LAQ-L
VI--GSD-WEVLLVPDKKQRT------FGPPPTXXXXXXXXXXX--XXXXXX--------
---------------------------------------XXXXXXX---XXXX-XXGSEE
WDDT--QDFQG----LQ-EVEAGAQALQQMELEL-SRQLREGLAAVL--RSPPALQA---
LEESLEQGLCY---GRAEPLDGPAGAVLECLVLPSRELV--QELAVPICYLVGAL-A---
-----------------------------VLNDTQRALL-AMA------LETGALPGQLD
LVTS----VLQQG---S----PWQQCRAISLPPELL----G-HNWG-Q--EVLAWILL--
-----EECGLEL--QVG-APHVCW---EPPAQDPTC-ALYASLVLLSGLGQEPS------
-----------------------------------------------

--------------------------------------SGRASWAGPASGCSFSFSSGHL
--------------------QLL-LAGRLPGRADAPDAPPSG-----RRRSRSMGS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFER
VVRRVVQELD-HGGEFIPVTSLQSSTGFQPYCLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------T---P--EPDVQRGR--
--------------------------------------SFHFYDAMDGQ-IQGSVELAAP
GQA-----KIAGGAA---------VSDSSST----------SMNVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKVLQQLRSRG--DNVYVVTEVLQT----QKEVEVT---RTHK
REGSGRFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--DSD-LDVLLFPDKKQRT------FQPPPTGHKRSTSEGAW--PQLP----------
--------------------------SG----------LSMMRCLH---NFLT-DGVPAE
GAFTED--FQG----LRAEVETISKELERLDREL-CQLLLKGLEGVL--RDQLALRA---
LEEALEQGQSL---GPVEPLDGPAGAVLECLVFSSGMLV--LELAIPVVYLLGAL-T---
-----------------------------MLSETQHKLL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQERSTMSLPPGLL----G-SSWG-E--GAPAWVLL--
-----DECGLEL--GED-TPHVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MGSAFER
VVRRVVQELD-HSGELIPMTSLQNSTGFQPYFLVVRKPS--SSWFWKPR-Y---------
-KCVNLSIKDILEPD----------------------------A---P--EPDLQRGS--
--------------------------------------TFHFYDAVDGQ-LRGGVELSAP
GQA-----KIAGRAS---------VSDSSST----------SMHVY-SLSVDP-NTWQTL
L-HE------RHLRQPEHKILQELRSRG--DNVYVVTEVLQT----QEEVEVT---RTHR
REGSGQFSLPGAMCL------QG-EG---QG--HLSQKKTVTI-PSGSI-LAFR-VAQ-L
VI--NSD-LDILLFPDKKQRT------FQPPPTGHKPSRSVGAW--PQLP----------
--------------------------SG----------LSMMGCLP---NFLA-DGVPAE
GTFTED--FQG----LRAEVEAISKELELLDREL-CQLLLKGLEGVL--RDQLALRA---
LEEALEQGPSL---GPVEPLDGPAGAVLGCLVLESRMLV--PELAVPIVYLLGAL-TSER
PLGVGGEWEGERWAFPDGPSGTPSYLT

PF04598 // ENSGT00530000063218_Domain_1 (748, 864)

LPVLSETHHELL-AEA------LESQTLLGPLE
LVGS----LLEQS---A----PWQKRSTMSLPPGLL----G-SSWG-E--GAPAWVLL--
-----EECGLEL--GED-TPYVCW---EPQAQGRMC-ALYASLALLSGLSQEPH------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MSST

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FEW
AAKNVVRELS-KKGELIPVDSLKSSTCFSPYYLVRKKIKS--TWFWKSR-Y---------
-AWLNLTLEDILEPG----------------------------S---P--KLEVTQG---
-------------------------------------ETFLFNDEMDGQ-VSGSVE--VA
-ASVQG--KISGQT-----------SVSNKS----------CLEVK-ILTVPP-TTWDCL
N-MK------RKLKKSQPSKFKELQTRG--ENLYVVTEAVQT----QKEAVLK---RSKN
RQGSGKITI-----PGAS-CIQG-EG---TG--QLNTMKTVKI-PEGSI-LAFQ-VVK-L
II-R-DR-WSVVQIPDKTQ------KTFQNAGIAAKS-----------------------
--------------------------------------------SG---YYSDACKTVT-
VS--SVKSLEQ----LQAQLEDEEKVLDMLNVEL-RMFLLKNFLEVL--KNEQDLLD---
FEDMLENSLYTG--VTPKDVNGPSGNLLSHLQDSDGKLL--NELSGAFLYLTGAL-N---
-----------------------------ALSDVQHQAL-IKIQSLEKEEKEKIMSQEIQ
LVEE----ILKKNFDQ-----TEE--TTFSYPSELV----S-LVQGQSDMSIRTRELL--
-----EECGLWF--SED-KAQLTW---DPCALHSLC-ALYGSLMILQFLTNA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFER
ISKNLIKEIG-S-KDLTPVKYLLSATKLRQFVILRK-KD-SRSSIWGQSDY---------
-VPVGFSLNDILEPS----------------------------S---S--VPETVVTG--
--------------------------------------PFHFSDVVIQK-HKA--DVSVN
-VGVEV--SVSGEA-----------SVDHGC----------SLEFQ-IVTIPS-PNLEDF
Q--K------RKLLDPEPSFLKECRRRG--DNLYVVTEAVEL----INNTVLY---NSSG
VNILGKIS-LWITYG------KG-QGQ-GES--LRVKKKALTL-QKGMV-MAYK-RKQ-L
VI-KEKA----ILISDDDE-----QRTFQDEYKISQR-LVSCAAR-SEEWLPSFHTISPT
LFNA-SPK-DM---TLKPELFLKPK---FL-----RGH--LPKYEQ---VCILPVGRIEE
-P--FWQNFKH----LQEEVFQKIKTLAQLSKDV-QDVVFYSILAML--GDRGALQD---
LMDMLEL----D---SSGHLDGPGGAILKKLQQDSNCAW--FNPKDPILYLLEAI-M---
-----------------------------VLSDIQHDLL-ACS------VEMRILLQQQE
LVRS----ILEPNFRY-----PWS--IPFTLKPELL----A-PLQSEG--LAITYGLL--
-----EECGLRM--ELD-SPRSTW---DLEAKMPLS-ALYGTLSLLQQLAEA--------
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------L

PF04598 // ENSGT00530000063218_Domain_1 (599, 857)

EE
-E--EERDFRV----LQAEVEMEMYALKALTLGQ-REGLLTALLGIM--GQAKALQT---
LEDTVSLG---E---GQGGLAEPGSAILPILKEDSGRLN--PTLSGTVLYLLGAL-R---
-----------------------------ELSEEQQQLL-AMS------VEKEILPQQMR
LLET----ILEQHFLR-----EES--GPGQLHSALL----S-GLRGEE--WAVTQALL--
-----SLSGLDL--DEN-ELLFTF---DPEALPQLS-ALYAALSIFHLLAKT--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPY

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

TFDW
LSKEVVKKLQ-G-RDLRPVKSLADATKFRLFYILQETS---PWLAFKTE-Y---------
-IPVEFTLLDVLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PIPLKHTVSQK-LKA--NVDVE
-----P--IAGGDAG---------FVKSGGY----------DIEVQ-SMSIPN-KKLESL
Q--N------RKLLDKLPSYMKNCCIEG--KNLYVVTEAYEV----TKDTVLE---GKCS
VNILGKGSIKQLFKI------GG-SG---QW--QTERTDSIPI-LKGSV-LAYK-KQQ-L
VI-EDNT-CAILPSANAKK-----KMTFANRPMYLSG-HFEI-LR-HHEE----------
--------------------------------------IIRIGSRI---EYISPIGTIEE
-P--THLDFQC----LQNEVSQKTMLLAELSKDV-QEVVFSSFLHMLCEGDSEVLYD---
LMKMLEL----N---QLEHMDGPGGKILEELQKDRSPSW--IDLKDLILNLLQAL-M---
-----------------------------VLSNTQLSLL-AQS------VEMRLLLQQQE
LVKS----ILQPNYKY-----PWH--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---HLEVKMPLS-ALYASLSLLQQLSEA--------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 800)

MFEG
CTRTVVQEMD-PGGDMIPVRSALDADRFCCFWLVREK-----------------------
---RDLTLMDILETE----------------------------EGEGP--CDELDSGLQ-
------------------------------GQ-KA---EFQILDTVDST-GKLTVKLLEE
-ISI------AGEL-----------QGSHEQ----------KIKIL-KNQISQ-QYLETL
V--N------RQLKKKLPPSFQSLHTRR--EDLHLVTETLET----VNKETLK-------
--SKWQYGFLSQIYQ---AL-------------HLN-YGKVTI-PSNQV-LDYR-LKQ-L
IF-PNEK-E---------------------------------------------------
------MSIYFWGKT-----KSFPE---------------GESKAC----WAVSIG--K-
SL--SSEDSRN----MKEKVHDTVRSLQDLTEKE-QRDVLSSLTKCL--SKDEHLED---
LEQRVFEALKSR----ALQMEGSAGPLLSSLFNTVGSLV--DGRAKAILDFLDAL-G---
-----------------------------ELSE-KKQLV-SEA------LEKGILPLLKD
EVKS----GMEKVWDKQ-ASNPHD--MTHDPE----------------------------
-------------------------------LS-----------------SEPTSASS--
-----------------------------------------------

MGYS

PF04598 // ENSGT00530000063218_Domain_0 (5, 114)

FDRASKDVVKKLQGRYLRPVECLSDATKFRLFHILQETPRSGWETEDIPV------
----GFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLESNLNVADIAGGGVGNMGYSFDR
ASKDVVKKLQ-G-RYLRPVECLSDATKFRLFHILQETP----RSGWETE-D---------
-IPVGFTLLDLLEPN----------------------------F---P--VPEPEVSA--
--------------------------------------PKPFIHVQSTD-LES--NLNVA
-----D--IAGGGVG---------YVGYGGY----------NIEVQ-SKSIPS-PKLENL
Q--N------RKLLDKLPTFMKICRMER--KNLYVFLF----------------------
------------------------------------------------------------
------C-PV

PF04598 // ENSGT00530000063218_Domain_1 (491, 864)

ILPSAT-KK-----KMTFPGTPKYASA-S-EPTET-SRT-----------
---------------------------------------QLEGLWI---NDIEPIGRIQE
-P--AHLDFKC----LQYEVSEQTRLLPELSKDV-QEVVLSSFLSMLYEGDRNVLHD---
LMKMLEL----N---QLGHMDGPGGKILDELRKDSSNPC--VDLKDPILYLLQAL-M---
-----------------------------VLSDSQLNLL-ARS------VEMGILPHQVE
LVKS----ILQPNFKY-----PWN--IPFTLQPQLL----A-PLQGEG--LAITYELL--
-----EECGLKM--ELN-NPRSTW---DLEAKMPLS-ALYGSLSFLQQLRKANSSSKPSL
RPGYI------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------M

PF04598 // ENSGT00530000063218_Domain_1 (631, 864)

PGEQ-KTTLFCAFQELL--GNRNALQD---
LEDMLDHALNSG---ILEKMEGPGRKILSNLQDSSGNLI--RSHISDLLYFLGAL-G---
-----------------------------VLSDKQHNLL-VQS------LEKKILHQQLK
LVRS----ILEANFNQ-----SQG--NPFFLQSEHL----S-QLHGED--LDITLGLV--
-----EECGLNL--QRV-DQQVTW---EPDARNHLC-ALYGVLSCLLLLTNTLLSTVKFP
HFI--------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPSS

PF04598 // ENSGT00530000063218_Domain_1 (118, 864)

FGH
VSETVAKEVG-C-KETRPVKYLSSANKFHLFSILRKKS---SALLKRRSEY---------
-VPLGFTLLDILQPS----------------------------L---S--VPVTGGFK--
--------------------------------------PLPYV--VIYN-PNI--SVSVN
-VGAEV--SASGEC-----------SEDHEY----------SLDYQ-IVSISS-PNLEDL
L--K------RKLVDPEPQYLSECRDRN--DKLYVVTQTIEV----VKDTVLY---NSNN
AFNI----VLSGFSP------QS-QGE-GQY--LKKSVKKLSL-QTGMV-MAYK-MKQ-L
II-NPST-FSILSTSYGS------QLTFQDRELPKFR-FL-----------------RKT
VSF------EVQVGA-------------------------TGQKWV---SKRQKRGTIFS
-R--LGFDFGD----LQNEVSSKTDALSGLSKNI-QHVVFHSVLAML--RDQRALEN---
LEDMLES----D---SLCHLDDPLCNILNELQQNSSPA------EHAILGLLEGI-I---
-----------------------------ELSDIQHYFL-ALS------MEKRIMGHQRE
LARS----ILEHHFEY-----LEV--VTFTLNPELL----A-PLQEED--VAITCGLL--
-----EECGLKI--EPN-SRRYHW---DPSAKMSLS-ILYGVLSLLQELAEASALQLPGL
LPGYA------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MAS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFNG
VVRSVIRELD-PRRELSTVDSLESASNFQPYHLLMKKLS--RQWFGRSR-Y---------
-SCINLSIQDILEPR----------------------------------------LVS--
--------------------------------------TFHFLDLVDGQ-LQGSVELAAA
SQG-----MLKAGAS---------MSNSSSA----------SMHVA-KLQVDP-HTWTTL
Q-QK------TRLQNPEPKILQQLRQYG--VNVYVVTEVLRT-----EEVEAT---RTRK
HEGLGQFALPGLSLQ------XX-XX---XX--XXXXXXXXXX-XXXXX-XXX-------
---------XX--X-XXX--X------X--XXXXXXXX----------------------
--------------------------XX----------XXXXXXXX---XXLS-DRVGRT
KNE-TVEGFRL----LEAEVEDQAEGLCVLSREL-CRQLLQGLDTVL--RDETALQA---
FEEALEEGVCS---GHVEKQDGPVGTILECLVKSSRELE--EELTKHAVYLLGAL-S---
-----------------------------ALSAAQRALL-AQE------LQARALSEPLS
LVQS----LLKQA---D----PWQQGREVTLPAAPP----G-SQWG-A--GAPTWILL--
-----EHCGLRL--QED-APQVHW---VPEALEAVH-ALYACLVVLSRLSQDL-------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFRCFHLVGEKRT-----FFGCR-H---------
-YTTGLTLMDILDT-----------------------------DGDKW--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDST-GELIVRLPKE
-ITI------SGSF-----------QGFHHQ----------KIKIS-ENRISQ-QYLATL
E--N------RKLKRELPFSFRSINTRE--N-LYLVTETLET----VKEETLK-------
--SDRQYKFWSQISQ---GHL---SY------KHKG-QREVTI-PPNRV-LSYR-VKQ-L
VF-PNKE-T---------------------------------------------------
------MNIHFRGKT-----KSFPE---------------EKDGA------SSCLG--K-
SL--G

PF04598 // ENSGT00530000063218_Domain_1 (606, 795)

SEDSRN----MKEKLEDMEGVLKDLTEEK-RKDMLNSLAKCL--SKEEIRQD---
LEQRVSEVLISR----ELHMEDPDKPLLSSLFNAAGVLV--EARAKAILDFLDAL-L---
-----------------------------ELSE-EQQFV-AEA------LEKGTLPLLKD
QVKS----VMEQNWDEL-ASSPPD--MDYDPE----------------------------
-------------------------------ARILC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 875)

TFEE
ITTVVIQQLD-SGGDMIAVRSVIDADRFQCFCLVREKRS-----FFGTQ-Y---------
-CKTDLTLKDILESE----------------------------ENKRL--TDELDSKSP-
------------------------------XXXXX---XXXXXXXXXXX-XXXXXXXXXX
-XXX-------XXX-----------XXXXXX----------XXXXX-XXXXXX-XXXXXX
X--X------XKLKSKLLPSFQSIQAKK--KDLYLVTETLET----KNEETLR-------
--SNQKYKFLG-------GNP---EF------EQKH-KREATI-PVKWV-LGYR-IKQ-L
VF-PNKE-TMXXYLG---------------------------------------------
--------ICFSGKT-----KSFPE---------------G-----------------K-
YL--NLGDVRS----MKETVQDMERSLQDLTEEE-RKDVLGCRTMFL--SKDGQLQD---
---QVSEVLSSG----ELQTEGSTSPLLCSLFNAAGILV--EARAEAILVLLDAL-L---
-----------------------------VLSEEERQLV-AEA------LEKEILPQVLD
QVET----ILAQNWGGQ-LGTPDD--MDRDPG----------------------------
-------------------------------QRSIC-AHYVVVSILLQLAKGPTSAPS--
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MPS

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

AFES
VVQSVVRELD-PRRELIPVDSLQNSANFRPYYLVRRKPP--SSRFWKPR-Y---------
-LCVNLSIKDILEPD----------------------------A---P--EPDLEHGS--
--------------------------------------TFHFFDTIDGK-MQGNMEVAVP
GQW-----KVSGGAA---------VSGSSST----------SMNVR-TLSVDP-NTWDHM
Q-QE------RRLRQPEHRILQQLRSRR--EDVFVVTKVLQT----QEEVEIM---RMRK
QEGSGHFVLPGPMCL------KG-DG---EG--HLMWENKVTI-PAGSI-LAFQ-VAQ-L
VI--RSD-WDIFPFPDEKQRT------FLPSPRGSQPQNT----------FSL-------
-----------------------S--SV----------LRAISDSL---KLLT-DGISEE
SVVTEE--FQV----LRTEVEAGSAALRNMARDL-RQQLLLDLGKVL--CDPPALQD---
LEALLAQGLCGN--GQVKPLEGPAGDILECLVLPSQVLV--QALAAPVFYLLGAL-T---
-----------------------------ALSETQQQLL-AKL------LDKGDLSTQLE
LVEH----LLEQS---T----PWQEQSDVSLSPKLL----G-SNWG-E--EAPAWALL--
-----EKCGLEL--QVG-APQVHW---EPQAQGPTC-ALYASLALLSGLS----------
-----------------------------------------------

--------------------------------------SPDCFPRS--------------
------------------------------------------------------------
------------------------------GTAGSQRPS--RFNFWRNC-SPRPPPSSFP
TTCPGSRFLPWLLPDCDWSHPPGLALPFRLALSGGLSRAGWPFA---R--PPCLETTS--
--------------------------------------RQSAG-AREHG-LRGGGPERAA
GAGPQA-RAHRGGQPARLRHLPALLPGEQEAPELVVLETPLHVPQP-VHHGHP-GAWC--
P-GA------

PF04598 // ENSGT00530000063218_Domain_1 (371, 864)

RRLRQPEHKVLQQLRHRG--DNLFVVTEVLQT----QKEVEIT---RTQK
QEGSGQFALPGAICL------QG-EG---QG--HRSHKKTVTI-PAGST-LAFQ-VAQ-L
VI--GSD-WEIVFFPDKKQRS------FQPPEEARREQHQPASC--FL------------
--------------------------SP----------IRIIWRGF---PFQA-DGVAEE
GAVVT-EDLQG----LRAELGAQCRGLECLSGDL-CQVLRAALGQLL--QDAPALQA---
TEAALEQGLRC---GRLERQDGPMGAVLECLVLPSREVV--QKLAVPVLYLLGAL-A---
-----------------------------VLSEGQQLLM-AQA------LDTGALQGPLE
LVES----ILEQS---E----PWQEPTDVSLPPGLL----E-GGWE-E--GAPTWALL--
-----EACGLRL--QRG-APQVCW---EPQAQAQVC-ALYVSLALLVQLNQDPS------
-----------------------------------------------

------------------------------------------------------------
-----------------------------------------------------MFSVFEE
ITRIVVKEMD-AGGDMIAVRSLVDADRFRCFPLVGEKRT-----FFGCR-H---------
-YTTGLTLMDILDT-----------------------------DGDKR--LDELDSGLQ-
------------------------------GQ-KA---EFQILDNVDSK-GELIVRLPKE
-ITI------SGSF-----------QGFHRQ----------KIKIS-ENRISQ-QYLATL
E--N------RKLKRELPFSFRSINMRE--N-LYLVTETLET----VKEETLK-------
--SDRQYKFWSQISQ---GHL---SY------KHKG-QREVTI-PPNRV-LSYR-VKQ-L
VF-PNKE-M---------------------------------------------------
------MNIHFRGKT-----KSFPK---------------EKDGA------SSCLG--K-
SL--

PF04598 // ENSGT00530000063218_Domain_1 (605, 795)

SSEDSRN----TKEKLEDMESVLQDLTEEK-RKDVLNSLTKCL--GKEEIRQD---
LEQRVSEVLISG----ELHMEDPDKPLLSSLFNAAGVLV--EARAKAILDFLDAL-L---
-----------------------------ELSE-EQQLV-AEA------LEKGTLPLLKD
QVKP----IVEQNWDEL-ASSPHD--MDYDPE----------------------------
-------------------------------ARILC-ALYVVVSILLELAEGPTSVSS--
-----------------------------------------------

------------------------------------------------------------
------------------------------------------------------MT

PF04598 // ENSGT00530000063218_Domain_1 (117, 864)

MFEN
VTRALARQLN-PRGDLTPLDSLIDFKCFHPFCLVLRKRK--STLFWGAR-Y---------
-VRTDYTLLDLLEPG----------------------------N------TPS-DPTD--
------------------------------------GGNFSFKNMLDAR-VEGDVDVPKT
-------VKVKGTA-----------GLSQSS----------TLEVQ-TLSVAP-KALESL
H-KE------RKLS-ADHPFLKEMWERG--ENLYVVMEVVET----VQEVTLE---RAGK
AE--GCFSLPFFAPLGL------------QG--SLNHKEAVTI-PKGCV-LAYR-VRQ-L
MV-NGKDEWDIPHVYNDSMQT------FPPGEKPGEGKFI--------------------
--------------------------------------------L----IQASDVG----
-E--MHDDFKT----LKEEVRRETREIEKLSQVG-RSSLLTSLRHLL--GKKKELQD---
LEHTLEGALDKGHEV---TLEALPKDV---------LLS--KDAMDAILYFLGAL-T---
-----------------------------VLSEAQQKLL-VKS------LEKEILPLQLK
LVES----TLEQNFLQ-----DKE--GVFPLRPDLL----S-SLGEEE--LTLTEALV--
-----GLSGLEV--QRS-GPQYTW---DPDTLPHLC-ALYAGLSLLQLLSMGS-------
-----------------------------------------------