Query Results 

------------------------------------------------------------
--------MIWLFQSLTL------V-SCLGPG--

PF07686 // ENSGT00530000063114_Domain_0 (95, 289)

-NT-VSQ-TSSTP-LIVNGVLGESVT
LTLKFPVEEKITSITWL-HEGK-S----AIFIEPNE------------------------
--------------------------A---LNRVTDPKRKNRLNVT----E-SY-SLQLS
NLTMADSGLYRAQITTLT--S-----SLFTDYDLRIFR--RL-RNLQVV-----PHT-KW
SNN-RTCEILLTCSVENPNDNILFRWQ--VSGN-T--------------------L----
QSEANLTISWDPKSFNE----ETYTCVAENAVSNSS-FSVSVQ--SLCKSVTNEKNE---
----------H-LDTMWIVVAVS-------SICIVVVI-IV---LLFVWR-KK-------
----S-------FF-QFSTQQT-QCPAETV--RNVEYASFSPG-STVYAQVTHSK--REM
EIP---KPVKNN-DSTTIY-S----EVQQSQE----------------RKP------TY-
---SRTTALHSVM-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALPWLLLLLLL----------R----AAEG-YSGD-DVDA-EEVVGVLQESIS
LPVEIPADEEVENIIWS-SS--AS----LAVVIPGR------------------------
-------------------------EGQPTKIVLTNPRYQRRVSLVG---P-DY-SLCIS
NLSWEDSGLYYAQVNLRT--SQ---ASSMQRYSLRVYR--RL-SEPHVS----

PF13895 // ENSGT00530000063114_Domain_2 (294, 399)

-VNF-EM
AAE-ESCNLSLACSVEEAGQDVTYSWI--SRDD-C--------------------RD-TV
HEGSALSTSWRPGDSVP-----SYTCRATNPVSTIYSQPIPAR--SFCTDPHFP-EETS-
--------------TYSCLLAKG-------L-LLLLLFAILGAGLWCVR----AQ-RGCQ
TPRTR-------KL---ERNR-----LRL-------RRKEQPSPSLA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ADLKRYW-----CDWAL----------GPLSENSRM
SQQQIFSPILWTPLLFLL----------T-----GLG-ASE-KET

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

PP-TVISGMLGGSVT
FSLNISKDAEIEHITWN-YP-PKT----LALVSY-K------------------------
-----------------------------KDITILDKGYNGRLKVSE---D-GY-SLYMS
NLTKSDSGSYHAQINQKN--VI---LTTNKEFTLH

ENSGT00530000063114_Linker_0_2 (276, 285)

IYE--KL-Q

PF13895 // ENSGT00530000063114_Domain_2 (285, 402)

KPQII-----VESVTP
SDT-DSCTFTLICTVKGTKDSVQYSWT--REDT-H--------------------LN-TY
DGSHTLRVSQSVCDPDL-----PYTCKAWNPVSQNSSQPVRIW--QFCT--GASRRKTAA
GKT----VVG--------ILGEP-------VTLPLEFR-ATRATKNVVWV-FN-----TS
VISQE---------------RRGAATADSR--R----KPKGSEERRVRT----SDQDQSL
KI----SQLKME-D-AGPY--HAYVCSEASRDPSVRH--FTLLVYKRLKKP----SVTKS
-SVHMMNGICEVVLTCSVDSGGNNVTYT--------WMPLQNKA---VMSQGKSHLNVSW
EIGEHLPNFTCTAHNPVSNSSSQFSS-GTICSGPERNK---RFW--LLLL--LVLLLLML
TGGYVILRKKKQCSSLAT-----RYRQAEVPA-EIPETPTGHGQFSVLSQRYEKLDMSAK
TTRHQPTPTSDTSSESSAT-TE---EDD----EKTRMHSTANSRNQVYDLVTHQDIAHVL
AYEGQAEYEAITPYDKVDESMDEEDMAYIQVSLNVQGETPLPQKKEDSNTIYCSVQKP-K
KTAQTPQQD-----TESPETPTYENST------

------------------------------------------------------------
----MAGFCTF-IIFTSV--------LCQIPV---TAKTSG----TL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KEMVGALGGSVT
FSLNFTG-KQVDTIVWT-FKTL-S----FAII----------------------------
---------------------------VKDKVIVTQNHNKERIVFPD---G-SY-SMTLS
QLKKNDSGVYRAEIYSTS--LE---SPFTQEYVLYVYE--YL-SRPKVT-----LNG-QD
NIN-GTCTTNLTCSMDKGGENVTYSWK--AIGH-E--------------------VN-ES
HDGAVLPISWRLGEKDK-----TLICMARNPISQSSSIPTHVQ--DLCGDAAK-DLNSS-
-------------SIILYILPVL---------IALG--LLLVIIPVAMHT-EK-----GK
VSKEH------------------MENVDIH--QKKPNFCPHLEENPEYDTIPYMNET---
-NM-----EEV--AANTLY-S----TVQIPKV---------------VRTF------IAD
---SH-PNCQSL----F---------LAHVQ-----------------------------
------------------------------IY---IS-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MVGLPVCL-ILVFL--------FCQ-------------------------------
-------

PF07686 // ENSGT00530000063114_Domain_0 (128, 277)

-LTVGSIVWI-FNST------LVTFQPRK------------------------
-----------------------------ATIIVTQSHKEERVSFRN---G-EC-SLTLS
KLQKSDSGTYRVEVHSTV--K----RFFTQEYVLRVYE--HL-SKPKVT-----MGL-EN
TKN-GTCTVNLTCSLEQQGEDVTYSWK--SLGK-A--------------------AN-ES
HVGAIFPLSWRLGE-NM-----TFICEATNPVSSNISHPVSSW--KLCEGA-AEGSGVP-
-------------TTLLYYLLMF----------VLCILILGLLL--MIQR-MR-----RK
VIAEK------------------IKGIEIH--QDIPTICSHLE-DALYDKITYPSKA---
-TP-----EED--LIHTLY-S----VVHIPKK----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MYAFPWLLLLLLL----------Q----E-------D-DVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLQESIS
LPLEIPPDDEVDNIIWS-SH--KT----LATVMPGK------------------------
-------------------------EGHPSTIMVTNPRYQGRVSLLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRS--SQ---ISIMQQYNLRVYR--RL-SIPHIT-----VNF-EI
SGE-GDCNMSLMCSVEKAGMDVTYSWL--SWGD-S--------------------TY-TS
HEGPVLSTAWRPGDSAL-----SYTCRASNPISNISSHTIPAG--PFCADPDYASKKPS-
--------------TDCCLLTKG-------L-LIFSLLVILATGIWVIQ----VQ-KRCR
I-------------------------MKL-------RRKAKPGSSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MRALP-CLFL-------------------LLL-LQED-DVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLHESTY
LPLEIPSDEEVEDIIWS-SR--KR----LATVVPEK------------------------
-------------------------EGHPATITVTDPHYQGRVSFLR---P-SY-SLHIS
NLSWEDSGLYQAQVNLGT--SQ---IFATRHYNLRVYR--RL-SEPQIT-----VNF-EI
SGE-RTCDMSLTCSMEKAGMDVTYSWL--CWGD-N--------------------TE-TV
HEGPVLSTSWRPGDSAL-----SYTCRASNPVSNVSSRPIPAG--SFCADPRYPSENPS-
--------------TAFCLLAKV-------L-LLLLLLVILAVGIWITR----VW-KRGK
MPRMK-------KL---RRNR-----MKL-------RKKRTPGPSPI-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALLWSLLL-LL----------Q----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVTGVLQESIN
LSLEIPSNEEIKHIDWL-FQ--NN----IAIVKPGK------------------------
-------------------------KGQPAVIMAVDPRYRGRVSISE---S-SY-SLHIS
NLTWEDSGLYNAQVNLKT--SE---SHITKSYHLRVYR--RL-SKPHIT-----VNS-NI
SEE-GVCNISLMCSIERAGMDVTYIWL--SSQD-S--------------------TN-TS
HEGSVLSTSWRPGDKAP-----SYTCRVSNPVSNISSRRISVG--SFCADPGYP-EKP--
--------------SMLCFLVKS-------L-FLLLLLAILTVGLCLFR----AQ-KSYE
MPRVR-------KL---KRNR-----IKL-------RKKGKSGPTPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCL-TLIYI--------LWQLTG---SA-

PF07686 // ENSGT00530000063114_Domain_0 (99, 274)

VSG----PV-KELVGSVGGAVT
FPLKPKV-KQVDSIVWT-FNTT-S----LVTIQPEG------------------------
-------------------------G----TIIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYSVGIYSSS--LQ---HPSTQKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCCMEHGEEDVIYTWK--ALGQ-A--------------------AN-ES
HNGSILPISWRWGESDM-----TFICVARNPVSSNFSSPILAR--KLCEGA-ADDPDSS-
-------------MILLCLLLVP---------LLLSLFVLGL-FLWFLKR-EK-----QE
ESIEE------------------KKRADIC--RETPNICPHSGENTEYDTIPHTNRT---
-IL-----KED--PANTVY-S----TVEIPKK---------------MENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------LT-----AATSP----------APV------
SSTER---MFWLFQSLPL------V-FCLGPG---HV-VSQ-ESS

PF07686 // ENSGT00530000063114_Domain_0 (106, 271)

TP-SIMNGVLGELVT
LPLKFPTGEKAMSITWL-YSGT-S----IAFIRLKE------------------------
--------------------------DQSSESHVTDPKRRERLSFT----G-CC-SLQLS
NLMMADTGSYRAQIATET--S-----TKFFNYTLRIFE--KL-RNIQVT-----NHI-QL
TEN-KTCEIHLACFVENSSDTVAFTWQ--TSGN-I--------------------H----
QHSPNFTISWDPRNSSE----DNYTCIAENPVSNLS-LSVSAQ--ALCKGIKK--NP---
----------D-SDSIWIIGTTV-------FAVILISA-VL--LCCIVWR-RI-----GR
FYLSD-------SH-HFSPQQA-QGPGK------------HPGSSTVYASVTHPNSNREM
ESP---TPMENN-DSVTIY-S----TINHSRE----------------DTE------SL-
---RTSPKLVGLLVNI--IFNYGD------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGTLPWLFLVLLL----------Q----EAKG-YSGDGV-

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

EP-EEVVAALQESVS
LPLEIPPGEEVKSIVWF-SQ--KR----LATVMPGK------------------------
-------------------------EGQPVSVVVDDPHYEGRVSFLG---P-SY-SLHIR
NVSWQDSGPYQAQVNLQT--SQ---LSTMQHYNLRVYR--RL-SQPQIA-----VNF-EI
PGE-GACNISLVCSVDRAGMNVTYSWL--TLGD-S--------------------AE-AA
QEGSGLSTSWRPGDKVL-----SYTCRASNPVGSINSLPIAAG--LFCADPGYR-ETPS-
--------------MPSCLLAKG-------L-LLLLLLIILAVGLC-------------E
VPRTR-------KL---KRNR-----IKL-------RKKEK-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLFVF-------CFGPG---NL-ISQ-SRS

PF07686 // ENSGT00530000063114_Domain_0 (106, 258)

TP-LMVNGVLGESVI
LPLEFPAGERIQSITWL-YNGA-S----LAFIVLSE------------------------
--------------------------TNSPKIHMTHPKQQKRLNFT----Q-SY-SLKLS
NLEMEDTGSYSAQITTET--S-----AKLSSYTLRIFR--QL-RNIQVN-----NYS-QL
FRN-RTCEIHLTCSVEDADDNVSFRWE--ALGS-T--------------------L----
SSEPNITTSWDPRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDVKI--Q----
----------Y-IDTKMILFVVF-------GTCIVTGF-II--VLLLVLR-KR-------
--R-D-------SL-PLSTQRT-QGPAESA--GNIEYISVSPVNNTVYASVTHSN--RET
EIS---TPIKN--ATVTIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVM-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFPWLLLLLLL----------Q----EAKG-DSGD-CV

PF07686 // ENSGT00530000063114_Domain_0 (106, 257)

DP-EEVVAVLQESIS
LPLEIPPEEEIENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVTNPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---ISTMQQYNLRVYR--RL-SEPQIT-----VNF-EN
SGE-GACNMSLVCSVEKAGMDVTYSWL--SWGD-S--------------------AY-TF
HEGPVLSTSWRPGDSAL-----SYTCRANNPITNVSSHPIPAG--PFCADPNYASEKPS-
--------------TAFCLLAKG-------L-LIFLLLVILAMGLWVIR----V------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCF-TLIYI--------LWQLTG---ST-ASG----SV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-T----LVTIQPEG------------------------
-------------------------G----PMIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFTRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCRMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICTVRNPVSSNSSSPILAR--KLCEGA-ADDSDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESIKE------------------KKRADIC--RETPNICPYSGENTEYDTIPYTNRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------IENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
MANLLQKWLLFFL--FYL----------F----TELY-ASG-EDLDS-Q

PF07686 // ENSGT00530000063114_Domain_0 (110, 255)

MLTGVLGESAI
LPLTIPKEKQITYILWT-SK--RS----LAIIEMGK------------------------
-------------------------EGNANKTTIIDPHYKERVNFLKQ-SY-NY-AMQIN
HLKMEDAGSYQAEITIAN--I---TEPMKKMFTLHIHE--RL-TEPKII-----PSL-KF
NDN-GTCLINLTCSVEQIRENASYSWM--SNRQ-G--------------------AN-IS
TRGPILTLNWKPGDHDL-----NYTCIARNPVSNSSCT-ILAK--ELCAGIEHGTHC-FR
V-------L---------Y-----------IVVPTILV-FLFISGLSFWH-IQ-----KK
KEKEA---------------D---------------IRDN------ECS----MYDS---
-I----SIL--N-P-DETE-TAEYVTVNSFKKNIQESLEAPNTLYATVQNT----TKMDK
-SEILERTQNL-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VASKSHT-----DDWGP----------GLFSDKPQR
SQLQIFSSVLRTSLLFLL----------L-----GLR-ASG-EDSAG-T

PF00047 // ENSGT00530000063114_Domain_0 (110, 269)

VVSGILGGSVT
LPLNISVATDIEHVTWN-GP-KNA----LALANP-K------------------------
-----------------------------G-VILMDKSYQGRLNITK---W-NY-SLHIS
NLTLNDAGFYKAQINKKN--SE---VTTKEEFTLRVYE--QL-QEPQVT-----LKSVKV
SEN-FSCNITLMCSVKGAEKSVLYSWT--PRDS-H--------------------AS-ES
NGSSILTISRMPCDPDL-----PYTCTAKNPVSQSSSRPVHAG--QFCTDPGASKGE-TM
GET----VVG--------VLGEA-------VTLPLALPVTCRDTEKVVWM-FN-----TS
IISKE---------------REEAATADPL--I----KSRDHSKNRVWV----SNQDCSL
KI----DRLMIE-D-AGPY--HAYVCSEASRVTSMTH--VTLRIYRRLRKP----KITWS
-IRHTEDGICRVSLTCSVEDGGNTVVYT--------WTPPQKEA---VVSQGKSHLDVSW
RSGENHPNLTCIASNPVSNTSHQFPS-ENICPGPKKNM---KLWIGLPLM--VCLLCLGI
FSWWCIWKQKRRF--PAF-----CSSQPKDPD-DTPEPTAGHTLYCMLPQEYEKLDPPPG
PARQHPMPTSDSSSDNNTTATE---EDD----DRPEMHMPINGRDRVYDEVPQEGAGHDS
APEAEADSDLVIPCATEVESVAGENTVYAQVSFNLQGKTPASQKEESSATIYLSIQKP-Q
TVVPPPQQDD----LEIPESPTYENFT------

------------------------------------------------------------
-----MGALLWSLLL-LL----------Q----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVVAALQESIS
LSLEIPSNEEVKDIIWF-SQ--KN----LVTVVPGK------------------------
-------------------------EGTPAVIIVMDPRYQGRVGISE---S-SY-SLHIS
NLTWEDSGLYQAKVSLNT--SQ---LSITKSYDLRVYR--RL-SKPHIT-----VNF-RI
SEE-GACNISLMCSVERAGMDVTYTWL--SPQD-S--------------------AN-MS
HEDAIISTSWRPGDRAL-----SYICRASNPVSNSSSHLIPVG--SFCADPGSP-EKP--
--------------SMSCLLAKG-------L-ILLFLLVILAVVLCVFQ----AR-KNYE
MSRVR-------KL---KRNR-----IKL-------RKKGKLGPSLD-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------LILGSVLLFF----------Y----KEAG-AFG-EESGP

PF07686 // ENSGT00530000063114_Domain_0 (108, 257)

-TRLNGAEGESVT
FAPVVPRGSRVDSVVWN-GN--ST----IAIVTP--------------------------
--------------------------GEPAPLRVIHTRYRDRLRVPD---G-SY-SLQVT
DLRPEDTGTYTAQIATQG--SP---DPIFRRFALRVYK--KL-AESDITAT-PVLGS-LS
IMN-EICNITLNCTVQGAGEDVNCTWN--HTDS-T-------------------------
VNSTSIHISHRLGDEGA-----SVTCTARNPVSSSSKSISLK---EVCAGNNLL------
-----------CYKHSFCLLGKS-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MPGPRACF-LLILL--------LCQFTG---PV-TSG----VL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KDLVGDLGGSVT
FPLKTPG-IQIETLVWI-FNTT-P----LITIQPKT------------------------
-------------------------PENQTNVIVTQSHNKERMDYLR---G-NY-SLKLG
KLDKSDSGDYSVLIYGSS--ME---EPFIQQYRLRVYE--HL-SKPKVT-----MGL-QN
NEN-GTCVTNLTCFMDQGGEDVTYSWE--SLGQ-E--------------------AN-ES
YTGSILPISWRLGERGM-----TFICVARNPISSNSSNPVFAW--KLCEGA-ADDPGPS-
-------------MFLYLLGLVF--------LFSTIAVALVS-VILIMRR-ER---RKE-
-SIEE------------------KKRMDTH--HEILNYYPPSGETPVYDTITGINDT---
-IP-----ECQQILANTLY-A----SVQIPQK---------------TEQP------QSP
---LTSPDTPRL----F---AYKNVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------------------------------------V
GSPVVPPFRFTL-----W--------FSVSAG---PV-TSG----AL

PF07686 // ENSGT00530000063114_Domain_0 (108, 261)

-KELVGDLGGSVT
FPLTLPG-IQIDSIVWT-FNTT-P----LITIQPRT------------------------
-------------------------PDRQANVIVTHSHNKKRVDFLH---G-NY-SLKLS
KLNKSDSGDYYVVIYSSS--

ENSGT00530000063114_Linker_0_2 (261, 285)

FK---EPFSQRYGLRVYE--HL-S

PF13927 // ENSGT00530000063114_Domain_2 (285, 390)

KPKVT-----MGL-QN
KEN-GTCVTNLTCFVDQGGEDVTYSWE--SLGQ-A--------------------AN-KS
YNGSILPISWRLGKGGM-----TFICVARNPISSNSSNPVFAW--KLCEGA-ADDSESS-
-------------VVLYFLGALL---------FMLTAFTLVP-FILFMRR-ER---RKE-
-SIEE------------------KKGMDTH--QEILNYYPPSGETPVYDTISCVNNC---
-IP-----EEN--SANTLY-F----SVQIPPK---------------MEKP------HSP
---PTSPDTPKS----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALPWLLFLLLI----------Q----EDKG-YSGD-DVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 261)

-EEVLAVLQESIT
LPLEIPSGEEVEDIIWS-SR--IR----LATVVPGK------------------------
-------------------------EGHPDTITVTNSRYQGRVSFLG---P-SY-SLHIS
NVTWEDSGSYEAQVNLRT--SQ---ISTTQRYNLRVYP-SHP-KEE-GS-----QDS-GL
WCE-AVCPTQMTWSSEVVGTKVALHVL--TSRG-P--------------------FS-PT
REGSVFSTSWRPRDNAL-----SYTCRAGNPVSNVSSRLIPAG--PFCADPGYPLEKTS-
--------------TSFCLLAKG-------L-LLLLLLVILAVGLWYIR----VQ-TRCK
TPRMK-------TL---RRNR-----MKL-------RKKGKPDPSWA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ADLKRYW-----CDWAL----------GPLSENPRM
SQQQIFSPILWIPLLFLL----------M-----GLG-ASG-KETPP-TVISGMLGGSVT
FSLNISKDAEIEHIIWN-CP-PKA----LALVFY-K------------------------
-----------------------------KDITILDKGYNGRLKVSE---D-GY-SLYMS
NLTKSDSGSYHAQINQKN--VI---LTTNKEFTLHIYE--KL-Q

PF13895 // ENSGT00530000063114_Domain_2 (285, 402)

KPQII-----VESVTP
SDT-DSCTFTLICTVKGTKDSVQYSWT--REDT-H--------------------LN-TY
DGSHTLRVSQSVCDPDL-----PYTCKAWNPVSQNSSQPVRIW--QFCT--GASRRKTAA
GKT----VVG--------ILGEP-------VTLPLEFR-ATRATKNVVWV-FN-----TS
VISQE---------------RRGAATADSR--R----KPKGSEERRVRT----SDQDQSL
KI----SQLKME-D-AGPY--HAYVCSEASRDPSVRH--FTLLVYKRLEKP----SVTKS
-PVHMMNGICEVVLTCSVDGGGNNVTYT--------WMPLQNKA---VMSQGKSHLNVSW
ESGEHLPNFTCTAHNPVSNSSSQFSS-GTICSGPERNK---RFW--LLLL--LVLLLLML
IGGYFILRKKKQCSSLAT-----RYRQAEVPA-EIPETPTGHGQFSVLSQRYEKLDMSAK
TTRHQPTPTSDTSSESSAT-TE---EDD----EKTRMHSTANSRNQVYDLVTHQDIAHAL
AYEGQVEYEAITPYDKVDGSMDEEDMAYIQVSLNVQGETPLPQKKEDSNTIYCSVQKP-K
KTAQTPQQD-----AESPETPTYENFT------

-------------------------MARTLT-----VLTSP----------TPF------
STAKS---MIWLFLSLLL------V-SHLGPG---NS-VSE-DSSPP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-LVVNGVLGESVT
LSSNFSEKENIMSITWL-HKGN-S----VIFISPKE------------------------
--------------------------A---KIQVTDPQRKDRLNVT----K-YY-SLQIN
NLTMADVGHYRAQITTST--S-----YLNTDYNLQIFR--RL-SNLQVA-----HHT-KR
SEN-NTCEIQLTCSVENPNDNVSFRWQ--VAGN-P--------------------Y----
HSETNLSISWDPKSLSE----ETYTCIAENPVSSLS-SSVSDK--SVCEGVINGKNE---
----------Y-LDIRWIIIVVV-------LTCIFFIA-LI---FVFVQR-RK-------
--VAG-------FF-QFSTQQT-QCPAETV--SNLEYASFSSG-NTVYAQVTHSN--KET
KSS---NPVKNY-DSTTIY-S----EVNHPQE----------------RKP------IY-
---SKTTAHHNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGAFLWSLLL-LL----------R----EVKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EDVVAVLQESIS
LSLEIPPDEEVESITWS-SQ--KN----LAIVVPGK------------------------
-------------------------EGQSTSIKVMDPRYWGRVDVSE---S-SY-SLYIN
NLTWEDSGLYQAKVNLKT--SQ---FSITTSYNLLVYR--RL-SKPHVT-----VTF-KI
SEE-GACNISLMCSVERAGMDATYTWF--SSQD-S--------------------TN-TS
REGSAIRTSWRPGDRAL-----SYTCRVSNPISSTSSRLIPVG--TFCADPGSP-EKS--
--------------PMFCLLTKG-------L-LLLLLLVTLAVGLYVFR----AQ-KNYE
MSRVR-------KL---KRNR-----IEL-------SRKRKPGPSQVP------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLFVF-------CFGPG---NL-ISQ-SRS

PF07686 // ENSGT00530000063114_Domain_0 (106, 258)

TP-LMVNGVLGESVI
LPLEFPAGERIQSITWL-YNGA-S----LAFIVLSE------------------------
--------------------------TNSPKIHMTHPKQQKRLNFT----Q-SY-SLKLS
NLEMEDTGSYSAQITTET--S-----AKLSSYTLRIFR--QL-RNIQVN-----NYS-QL
FRN-RTCEIHLTCSVEDADDNVSFRWE--ALGS-T--------------------L----
SSEPNITTSWDPRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDVKI--Q----
----------Y-IDTKMILFVVF-------GTCIVTGF-II--VLSLVLR-KR-------
--R-D-------SL-PLSTQRT-QGP-ESA--GNIEYISVSPVNNTVYASVTHSN--RET
EIS---TPIKN--ATVTIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVM-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALLWSLLL-LL----------Q----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVVAALQESIS
LSLEIPSDEEVKDIIWF-FQ--KN----LVTVVPRK------------------------
-------------------------EGKSTVMLTMDPRYRGRVGISE---S-SY-SLSIS
NLTWEDSGLYQAKVSLNT--SQ---LFITKSYDLRVYR--RL-SKPHIT-----VSL-KI
SEE-GACNISLMCSIERAGMDVTYTWL--SSQD-S--------------------TN-VS
HEDSVISTSWRPGDRAL-----SYTCRASNPVSNSSSRLISVG--SFCADLGSP-EKP--
--------------SMSCLLAKG-------L-ILLFLLVILAVVLCVFQ----TR-KNRE
LSRVR-------KL---KRNR-----IQL-------RKKGSPGPSPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQRYLWILLLC------------LQTCLG----ADR-SDTDV-VTLIGILGELVT
FPLNIEKSQQVVNIVWNS-E--TS----VAFITPGD------------------------
-------------------------AGAAPKVT

PF07686 // ENSGT00530000063114_Domain_1 (214, 269)

VTHQNYKDRINVSS---Q-NY-NLEIS
NLRMEDSGIYKADINTKT--FEGVFTTTTRRFNLQVFR--RL-GKPQIT-----QSL-MT
SLN-STCYVTLTCSVEKEEGNVTYSWS--PLGE---------------------------
-TGNVIRISRTPDSQEL-----TYTCTAQNPISNSS-DSISAQ--QLCADTATGLRSRRI
G-----------------LL-SG----LA--GLFLLIL-IVPLVLLFLLR-KRGE-----
----G------SFLKPFSKNSD-AASKKTIYTYVMVTRAAPPAEGRIYDEIPPSK-----
-E----LPANED-PVNRVY-A----TLQ-MEK---------------MGKT---------
---STQDGKPPG------ISAYENVV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-------MGSWLLLLLLL----------Q----EAKA-YSGDGV-

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

EP-EEVVAALQESII
LPLKIPPDEEVESIVWF-SR--KR----LATVVPGK------------------------
-------------------------EGYPGSVMVVDPHYEGRVSFLD---G-SY-SLHIS
NVSWEDAGSYQAQVNLQT--SQ---LSTTPHYNLRVYR--RL-SQPQIA-----VNF-EI
PGE-SACNISLACLVERAGADVTYSWL--TLGD-S--------------------AD-TA
QEGSVLRTNWRPGDKAL-----SYTCRASNPISSITSRPVTAG--PFCADPGYL-ETPS-
--------------VSSCLLAKG-------L-LLLVLLISLALGLWITR----IP-KKSE
VPRTR-------RL---KGNR-----IKL-------RKK---------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------MV-----VSRTP----------APD------
SAGQM---MVWL---FPL------V-FCLGSG---NE-VPQ-SS

PF07686 // ENSGT00530000063114_Domain_0 (105, 276)

QSP-RVVNGVLGESAT
LLLELPAGKEASLIIWH-HKGEASQDTTILIVQLNK------------------------
--------------------------SKTPRIIESDPKRGERLSII----Q-SY-SLQVN
NLTMADAGLYRAQITTKD--P----TPDFSIYKLRVFE--RL-SNLEIT-----NHT-RL
FEN-GTCEIHLTCIAENPNQTVSVGWR--TSGS-I--------------------S----
LGEPNLTVSWDPKNSND----QSYTCQAENAVSNLS-VSVSAQ--SLCKGVLPEKNL---
----------Q-WHQTF-----I-------IIGTLLAI-VVVCLVICLWK-K--------
--RTG-------SL-F-LASQH----PDSS--QNTD-TPGSPGSNTVYAQVTHPV--QVS
PFH---SVPHH--CYFTIT-HKLVTIIIHYWR----------------R-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----SFGEDLES-TLIYR--------FVVSTG---PA-ASG----AL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KELVGAIGGSVT
FPLNIKE-KQVDSIIWS-INTT-V----LVIIQPVE------------------------
-------------------------NE-QLNVIVTQNSNKERMEFPR-----GG-ELKLS
KLKKSDSGVYSAQIHSSS--SP----TITQEYVLRVYE--HL-PKPKVI-----LGL-QS
SKN-GSCTTNLTCFMEHKGEDVTYSWK--VLGE-A--------------------AN-ET
YDDSILPVSWRLGDKDM-----TFICIARNPISSNFSSPILVR--KLCEGD----PDSS-
-------------MVLLCSLMML---------MLLIVLVLGL-VLLSMRK-ER-----IG
EFIKE------------------KKRMDID--QEIPNFCPNSGETTEYDTIPCAEKS---
-IP-----KED--LANTLY-S----TVQIPKK---------------MEEP------YAL
---TTTPDTSKT----F---SYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQLLLF------V-FCFGPG---NV-VSQ-SSS

PF07686 // ENSGT00530000063114_Domain_0 (106, 256)

TP-LMVNGILGESVT
LPLEFPAGEKVNSITWL-CNGT-S----LAFIVPHE------------------------
--------------------------TKSPEIHMTNPKQGKRLHFT----Q-SY-SLQLS
NLEMEDTGFYSAQIATDT--S-----AKLSSYTLRILR--QL-RNIQVT-----NHS-QL
FQN-RTCELQLTCSVEDADDNVSFRWE--ALGN-T--------------------L----
SSQPNLTISWDLRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCRDVKI--Q----
----------Y-TDTKMILIVVS-------GICIVTIF-II--LLLLVLR-KR-------
--R-D-------SL-HLSTQRT-QGPAESA--GNIEYVSVSPTNNTVYASVTHSN--RET
EIW---TPIEN--DTITIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VAPKSYT-----QDWAP----------GPFSSKPQR
SQLQIFSSVLWTSLLFLL----------M-----GLR-ASG-KDSAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-TMVSGILGGSVT
LPLNISVDTAIEHVIWI-GP-KKA----LAFARP-K------------------------
-----------------------------ENVTFMAKSYRGQLNIAR---G-SY-SLSIS
NLTLNDAGSYKAQINQRN--FE---VTTEEEFTLFIYS--PFIEKVSV----------HV
IEG-DHCTLLE------GSGLESIIST--PAEP-R--------------------VS-VR
EG----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------LPRASLWAYF----------IGLGGRHAG-SSR-AEAGA-ME

PF07686 // ENSGT00530000063114_Domain_0 (111, 274)

LSGILGGSVT
FPTGVPAE-QFKTAAWT-VNTANS----IATVGA--------------------------
--------------------------GNPPALIVSHSSYEGRLTVSA---Q-NY-SLQIS
GLRAEDTGTYSAQITMAT--G----TVHRQNFTLRVYK--RL-AESDITVT-PVLGS-VN
TVN-GTCSITLNCTVQGAGEDVNCTWN--QTEA-S--------------------T--VI
STGPSIHISHRLGDEGA-----SVTCMARNPVSSSSKSISLK---EVC------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VGPKSHS-----DDWAL----------GPFSNKPQK
SQPQIFSSILWTCLLFLL----------M-----GLS-ASG-KDS

PF00047 // ENSGT00530000063114_Domain_0 (106, 270)

AP-TVVLGIIGGSMT
LSLNISGDTEIEHVTWN-GP-TNT----LIMAYP-K------------------------
-----------------------------GKITFVDKSYQGRLN-TS---W-NY-SLCIS
NLTLKDAGTYKAQINQKN--SQ---VTTEEKFTLHIYE--QL-REPQVT-----MKSAKV
SEN-SSCNITLRCSVKGAEKDVLYSWT--PRDP-H--------------------AS-ES
NDSSILTIFRMPCHPNP-----PYTCTVRNPVSESSSRPVRAR--QFCAGPGASRRG-AM
GET----VLG--------ILGEP-------ITLPLALL-ASQDIDNVVWM-FN-----AS
IISKG---------------QEEAATADPL--I----KSRDPFKNRVWV----SGQDHSL
KI----DPLKME-D-AGPY--HAYVCSKASRVTSTTH--VTLLIYRRLAKP----KVTWS
-LGHAKDGICRISLTCSVEDGGNNLTYT--------WAPLPEGA---LLSQGGSGLNISW
RSGENHPNFTCTARNPVSSSSSQFLS-GNVCPGPKSHV---KPWIVLSPV--VFLLCFVI
SS-WCIWRHKRQCGVGTFI-----SPA----P-CVPEPTA----------GHTKLGPPHK
PARPQPRPTSDSSSDSNIT-TE---EDE----ERPETHKPVNGGDELSDLVTQEGTGHDS
ASESQAEYDLTAPDDTTAESVVEGGTVYMQVFFNSQRQTPVPQKKDSSATIYDCVQKS-Q
MVVPPPQQNN----LESPEIPTYENLT------

-------------MAWMK------------------------------------------
-------VPPWLFFLVLL----------GPQEGKGQS-GEQ-EELDS

PF07686 // ENSGT00530000063114_Domain_0 (108, 252)

-KELMLVLGESVS
LPVNIEEGEEIEKIIWS-FH--ST----LAVIQQEA------------------------
-------------------------MKEPSISIVPDPRYNVIVNISD---H-TY-SLHIS
NLSKEDEGTYRAEMNFEG--FP---GTITQKFILRVYR--RL-PKPKVT-----VIL-EI
SEE-SVCNVTLKCHVDGKGDEEEFSWT--SLDP-G--------------------AI-VS
DGGSVLHLSWRPGDSDW-----TSTCIVRNPVSFSSHSLPVE---QFCTGPKVSSST---
----------SCSS-----LVKG-------LFIL---L-LF--GFLIVGI-IV-----TR
HLIKN----------KESATR--RIHR-------------------GLK----LRKG---
-V----KRENLQ------------------------VKEFP-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
------------------------------------S-VST-GTGAP-RELNGTIGGMVT
FPLDIPAGRRVTNIDWR-AK--QT----IAKVSPGE------------------------
-------------------------AGNLPKL

PF07686 // ENSGT00530000063114_Domain_1 (213, 257)

NFVLPQYKERLSVS----T-DY-SLTIS
NLRPEDAGTYRVRINTVN--ATSN-SFTNMEFSLRVYG--QL-VEPLVT-----VKS-LA
ADN-SHCTVILTCSMDREGDDVTFSWT--PRGR-G--------------------PP-CP
-------LKSPSSASPP-----SYTCMATNHNSNSFSSIPGLLCASH

PF07686 // ENSGT00530000063114_Domain_3 (408, 570)

CTKHWVSAGT-GA
SLELNGVVMGSVTFPLDIPAGRW-------VESI---I-WTSNGAIATV---I-----PG
GPGDP----------PNIIATTQRHSE-------------------RLS----VSTDYSL
TI----SRLRLE-D-AGHY--RADVSTADTTGTTTITSQFSLRV----YDP---------
----------------------ERGAFL--------WAGDMFL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----------------------------------ST-ASR-ENNAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 257)

-VVVTGILGESAI
LPADIPDKNKIDNINWA-SR--TP----VAVVT-PE------------------------
--------------------------GTAVNIITTHQNYKGRLNVSS---K-TY-DLQIN
HLKMEDAGFYRADINLKT--SSTS-TTITKNYTLQIYR--RL-EQPKIT-----LNT-IA
SEN-NTCNITLTCSVEIG-DAVKY------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VAPKSHT-----QDWAP----------GPFSSKPQR
SQLQIFSSVLWTSLLFLL----------M-----GLR-ASG-KDSAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-TVVSGILGGSVT
LPLNISVDTAIEHVIWI-GP-KKA----LAFARP-K------------------------
-----------------------------ENVTFMAKSYRGRLNITR---G-SY-SLSIS
NLTLNDAGSYKAQINQRN--FE---VTTEEEFTLFIYA--PFIEKVSV----------HV
IEG-DHCTLLE------GSGLESIIST--LAEP-R--------------------VS-VR
EG----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MEALPWLLFL-LL----------Q----EAKG-FSGD-DVDR-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

EEVLAVLHESII
LPLEIPFDEEVETIIWS-SR--KS----LATVVPGK------------------------
-------------------------AGQPAYVMVTDPRYKGRVNFPE---P-SY-SLYIS
NVTWEDSGVYEAQVNLKT--SQ---LFSTQHYHLHVYR--RL-SKPRVT-----VNF-EI
SGE-AACNISLTCSIERAGMEVTYRWL--SSGD-S--------------------TD-TA
HEGSVLSTSWRPGDTAV-----SYTCKASNPISNTSSHPIPAG--LFCAGPGSP-EQT--
--------------SMLCFLAKG-------L-LLLLLLAILAVGLWVFR----VH-KKCE
LPKVR-------KL---QRNR-----MKL-------RKKWQPGPSPI-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------MA-----VSRAP----------APD------
SACQR---MVWL---FPL------V-FCLGSG---SE-VSQ-SSSDL-RL

PF07686 // ENSGT00530000063114_Domain_0 (111, 261)

VNGVLGESAV
FPLTLPAGKTASVIIWN-YEGEASHGT-ALFINLNT------------------------
--------------------------PKSPDIIYIDR--RKTLNIT----Q-SY-SLQIS
NLTMADTGSYTAQITTKD--S----EMIVLRYTLRVFE--RL-GNLETA-----NNT-LL
LEN-GTCQIHLACAVNNQNQTVSVEWQ--ATGN-I--------------------S----
LGEPNVTIFWDSRNSGD----QTYICRAKNAVSNLS-VSVSTQ--SLCKGVLTNPP----
------------WNTVWFRTTVS-------IITGAVIL-IFVCWRIYVWK-R--------
---RG-------SL-P-LTSQH----PDSS--QGTD-APGSPG-NTVYAQVTRPM--QEM
KIP---KPIKN--DSMTIY-S----IVNHSRE----------------AEY------S--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MLKPHLWLLLFCLL---------------LGST-ASR-ENNAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 256)

-VVVTGILGESAI
LPADIPDKNKIDNINWA-SR--TP----VAVVT-PE------------------------
--------------------------GTSVNIITTHLNYKGRLNVSS---K-TY-DLQIN
HLKMEDAGFYRADINLKT--SSTS-TTITKNYTLQIYR--RL-EQPKIT-----LNA-LA
SEN-NTCNITLTCSVEIR-EAVKYEWT--PLGE-Q--------------------TA-ES
DGKSRLFIFQASGDVPK-----NYTCLATNPVSKNSQS-ILVK--NSCAGTLMISGP-PW
Y-----------------ALI-S-------VLEMLVIF-SLAGVGFYLWH-KI-----K-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

----------------MK------------------------------------------
-------VHPWVFFFLML----------LHSQEAGEG-QSG-EEPET-EE

PF07686 // ENSGT00530000063114_Domain_0 (111, 258)

LMAILGESII
FPINIPEGEQIEKIIWV-FQ--SP----LATIKKGA------------------------
-------------------------GEKLSTIIVSNPRYKVLVDIPD---Q-IY-SLQIS
NLSKEDEGMYRANIVSEN--AL---DTITRKFTLRVYR--RL-PKPKVT-----IYL-EI
SEE-FMCNVTLKCHVDGRGEDEEYGWT--PLGP-R--------------------AV-VS
NGGSVLHLSWKPGDSDL-----TSTCIVRNPVSLSSHSLQAG---QFCTGPRISSSA---
----------SCSP-----LAKG-------LFIL---L-LL--GILTVSI-IV-----IR
VLTKN----------KKAIER----IH-------------------RMK----LRRN---
-V----KREKMQ------------------------AKEFPLAS----RIP---------
----------------------E-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
MLHLISSLPAHRYMRPRK--------YQGKTG---PA-ACG----VL-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

KLVGAVGGSVT
FPLNLSA-NMIDSIIWV-FNTT-T----FVTIQPKM------------------------
-------------------------ADKKALIIVTQQRNKERVDFPN---E-SY-SLKLS
KLKKNDSGAYRVEIYSST--LQ---NPLSQEYELRVYE--YL-SKPKVT-----VGL-QN
NNN-GTCVTNLTCSTEEGEEDVTYSWI--SLGQ-A--------------------NN-ES
YGGSILPISLRREKRDM-----TFICLARNPISSNSSNPIFAW--KLCKGT-TGGLATS-
-------------GIFSILLS----------FILLCFLALML-IILIIRR-ER---RKA-
-SIEE------------------KGGVGTH--PEILSCSPPSGETLEYDTIPHLKNT---
-IP-----EEN--SLNTLY-S----TVQIPPK---------------VEKP------HSL
---PELPDTPGP----F---TYENII----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------AGPRRHP-----DDRAP----------RPFSNKPQK
TQPRMFSSFLWTCLLLLL----------T-----GPG-A

PF07686 // ENSGT00530000063114_Domain_0 (100, 277)

SG-KDSTP-TVVPGILGGSVT
FPLNISVDTEFEHVAWN-GP-QGA----LALATA-E------------------------
-----------------------------RKIFVTAKSYRDRLTISL---N-SY-SLSLS
NLTLEDAGSYKAQINWKT--SK---FTTDKEFKLHVYE--QV-PEPQVI-----MKSVNM
SDN-GSCNITLICFVERAGTSTLYSWT--PRDA-H--------------------AS-ES
HEGSTFIIHWRLCDPDL-----PYTCTARNPVSQNTSSPISAR--QFCTAPGASRGE-SM
GEM----VVG--------ILGES-------VTLPLTLS-ANHSGENAVWT-FN-----TS
IISKE---------------QKEAATADLF--I----KFKDPNKN--------SSQDYSL
II----GQLKME-N-AGHY--YAYVCSKASRVISTKH--VTLLVYGRLKKP----KITWH
-PGLAEDGICRFSLTCSVEDSGHNVTYR--------WTPLPKGT---VESQGGPHLNVSW
TSGENHPNFTCIASNPVSNSSQQFLS-GDICPGPKGNT---ELFIVLLVT-V-FIPCIAV
FI-WCIWKRKRLCSV---P--ASSSSRADTPA-DAPELTAEHTLYNMFSQGCQKLDTFPK
TAKQQHRPTPNSISDSSET-TE---KDQ----ERTDT--PKAGRHQENDLLSQEGTGSDS
ASEEQAEYELITPESMVPASA--DHTVYTQVFFNLQGKTPVPEQKESSTTIYSSLQTP-R
KVVLPPQQND----PESPNIPTYENFT------

------------------------------------------------------------
-----MGAFLWSLLL-LL----------R----EAKG-FSGD-EE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVIAVLQESII
LSLEIPSSEEVKDIIWS-SR--KN----LAVVAPGE------------------------
-------------------------EGQPANITVMDPRYRGRVGIPE---S-SY-SLRIS
NLTWEDSDFYQAKVNLKT--SQ---LSITKSYNLHVYR--RL-SRPHIT-----VNF-KI
SEE-GACNISLRCSVERADMDVTYSWL--SSQD-S--------------------TD-TP
HEGSVVSTSWRPGDEAL-----SYTCRVSNPVSYSTSRLIPVG--SFCAEPGYS-EKS--
--------------SVFCLLAKG-------L-LLLLLLVILAVGLCVFR----AQ-KNYE
MARVR-------KL---KRNR-----IKL-------RKKGKPGPSPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------------------------------------------------MSLFL
GLAAATGTFPWLFLLLLL----------Q----EAIG-YSGDSA-AP

PF07686 // ENSGT00530000063114_Domain_0 (108, 273)

-EEVVAALQEPIS
LPLEIPPDEEVESIVWF-SR--KR----LATVVPGK------------------------
-------------------------KGQPASVMVVDPHYEGRVSFLD---P-SY-SLHIS
NVSWKDSGLYQVQVNLRT--SQ---LSTTQRYNLCVYR--RL-SQPRVA-----VNF-EI
PGE-GACNISLLCSVERAGMNVNYSWL--ALGD-S--------------------AD-AV
QEGSVLRTSWRPGDKVL-----PYICKASNPVSSIHSHPILAG--AFCADPGYL-EMPS-
--------------VSSCLLAKG-------L-LLLVLLIILAVGLWVTR----VK-KKSD
LPRTR-------KL---KRNR-----IKL-------RKKRKPDCSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MIWLLRSLTL------V-FCLGPG--

PF07686 // ENSGT00530000063114_Domain_0 (95, 289)

-ST-VSK-SCANPRMTVNGVLGESVT
LPLEFPAEEKITSITWL-HNGT-S----ITFIQLKE------------------------
--------------------------TGSPHIYTTDPKRRERLNFT----P-SY-SLQLS
NLTMEDTGCYHAQKTSET--S-----AKISFYTLRIFG--LL-KNLKIT-----HST-AL
SEN-KTCKINLTCSVENPNDSVSFTWQ--PLGW-P--------------------D----
-----LTISWNPENSNE----QNYICIAKNPVSNLS-SSLSAS--SLCKXXXXXXXX---
----------X-XXXXXXXXXXX-------XXXXXXXX-XX---XXXXXX-XX-------
----X-------XX-XXXXXXX-XXXXXXX--XXXXXXXXXXX-XXXXXXXXXXX--XNT
SLR---KPRESK-NPTTIY-S----TVQQPKE--------K-----------------S-
---SRVPALDNIIY----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ADLKRYW-----CERAL----------DAFSEKTRK
SQQQIFSPILWIPLLFLL----------M-----GLG-ASG-KETPP-RVISGILGGSVT
FPLNISINAEIELITWT-YL-SKT----LVLAITSR------------------------
-----------------------------SGITILLKEYSGRLNISQ---D-GY-SLCMS
NLTKSDSGSYQAQIIQKN--VD---HTVRNEFILHIYE--QL-QEPQVT-----VKSMTS
SEN

PF13895 // ENSGT00530000063114_Domain_2 (304, 402)

-DSCTVTLICTVNGSKDGVQYSWI--QKDT-H--------------------NK-TS
HESHILRVSPSACDPDL-----PYTCTARNPVSQNSSQPVR

ENSGT00530000063114_Linker_2_3 (402, 422)

VR--QFCT--GTSRKK-TT
G

PF07686 // ENSGT00530000063114_Domain_3 (422, 582)

KT----VIG--------ILGEP-------VTLSLEFP-ASEETKNVVWV-FN-----TS
VISQE---------------PKGAATVDPH--R--H-KSKSSEERRLRI----SDQDSSL
KI----SQLKME-D-TGPY--HAYVCSETSRGPSVRH--FTLLVYQRLKKP----NVTQS
-PVHMTNGICEVVLTCSVEGGEKDVRYT--------WMPLQKET---VMSQGKSHLNVSW
KIGERLPNFTCTTHNPVSNSSRQLSS-GSLCSGPERNK---RLW--ILLL--LGLFLGML
IGGCFILKKRKLCSSLAI-----RNSQAKVPA-EIPETPAGHIGFSVLSQQYEKLDMPAK
TIRHHSTSTSDTSSESSAT-TE---EDD----EKTRMHSTVNGRSQVYDLFTQEDIAHDL
ASEGQAEYEAVSPDDKVAKSMDEEDTAYTQESLIVQGENPLPQKKEGSNTIYCSLQKH-K
TMVQTPQQD-----TESPETPTYENFT------

------------------------------------------------------------
-------------------------------G---PA-ASR----TR

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-KELVGALGGAVT
FPLNHSV-NEIDSIIWI-FNTT-P----LVTIQPNT------------------------
-------------------------PDGQANIIVTQNRNKERVDFLQ---G-SY-SMILS
KLKKKDSGVYRVEIHSSS--LQ---HPFTQEYGLQVYE--YL-SKPKVT-----MGL-QN
IEN-DTCVTNLTCSMEQGGEDVTYTWK--SLGQ-A--------------------TN-ES
HYGSILPVSWRLGKRDI-----TFICEARNPISSNSSNPIFAQ--KLCEGA-PRDPTSS-
-------------MVLKLLVV----------LFLLSAFALVA-IILIMRK-ER---GKE-
-FIEE------------------KKRTDNQ--QETLNYNPPSGETAEYDTVSHLNKT---
-VP-----EEN--LVNTFY-A----TVQIPPK---------------MEKH------DSL
---PTSPDTPKL----Y---TYENVT----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
---------TVQQPNGYN-------FLFMSSGLE----

PF07686 // ENSGT00530000063114_Domain_0 (99, 277)

AAE-SNTNM-LTVNGILGETVT
FPLNIQNIQQITNINWVSSK--TS----VAVVV-AL------------------------
-------------------------SGAPPHVIVTHQNYKQRVNVSS---Q-NY-NLEIS
NLRMEDAAIYRADINTKN--SEKE--TLTRTYKLQVYR--RL-GKPKIT-----HSL-TT
SWN-STCNVTLTCSMEKEEKNVKYSWS--PTGT---------------------------
-EGSVLQVFQTPNNQEL-----TYTCTAWNPVSNNS-DSISAQ--QLCADSPTGLRNQRA
G-----------------LL-SG----LA--VLFLVIV-ILSSVLLFLFC-KKGR---DC
-------------ASIFICDTD-AASKNTIYTYVNAPRNPQPEELRIYDEISPSK-----
-A----LPTKEK-PGNTTY-S----TVRYSD-----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLF------V-FCFGPG---NV-VSQ-SSLTP-

PF07686 // ENSGT00530000063114_Domain_0 (109, 267)

LMVNGILGESVT
LPLEFPAGEKVNFITWL-FNET-S----LAFIVPHE------------------------
--------------------------TKSPEIHVTNPKQGKRLNFT----Q-SY-SLQLS
NLKMEDTGSYRAQISTKT--S-----AKLSSYTLRILR--QL-RNIQVT-----NHS-QL
FQN-MTCELHLTCSVEDADDNVSFRWE--ALGN-T--------------------L----
SSQPNLTVSWDPRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCEDVKI--Q----
----------Y-TDTKMILFMVS-------GICIVFGF-II--LLLLVLR-KR-------
--R-D-------SL-SLSTQRT-QGPAESA--RNLEYVSVSPTNNTVYASVTHSN--RET
EIW---TPREN--DTITIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------FLWLRSF---------I-YKLFTG---NL-VSQ-S

PF07686 // ENSGT00530000063114_Domain_0 (104, 258)

SSTP-LMVNGVLGESVI
LPLELPAGQMIASITWL-CNGT-S----LAFIEPSE------------------------
--------------------------TESPKIHVTHPKQRKRLNFT----Q-SY-SLKLS
NLEMEDTGSYGAQITTET--S-----VKLSSYTLRIFR--QL-RNIQVN-----NYS-QL
FQN-RTCEIHLTCSVEDADDNVSFRWE--ALGS-T--------------------L----
SSEPNITTSWDPRISGE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDVKI--Q----
----------Y-TDTKMILFVVF-------GICIVTGF-II--MLLLVLR-KR-------
--R-D-------SL-PLSTQRT-QGPAESA--GNIEYISVSPVNNTVYASVTHSN--RET
EIS---TPIEN--ATVTIY-S----TVNHSKE----------------SKP------TF-
---SRATALDNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----SGKGRDSG-ILHGS-------

PF07686 // ENSGT00530000063114_Domain_0 (86, 277)

-LCVSTG---PA-ASR----DL-KKLVGALGGSVT
FPLNHSI-KKVGSIVWI-FNTT------LVTLQPQE------------------------
-------------------------SNKSAIVIVTQSHKKERVSFPN---R-DY-SLKLS
KLQKNDSGTYRVEIHNPL--HQ---LPFTQEYVLRVYE--YL-SKPKVT-----KGL-QN
KKN-DTCMTNLTCSMEQGEEDVTYSWK--I-------------------------AN-ES
HDGSVLPVSWRLGEKNI-----NFICVASNPISNSSSNPISSW--NLCEGT-AGDTNAP-
-------------MFLLYFLLAT----------LLSVLVFGLVLISSMQR-DR-----RK
EFTGE------------------KEGVEIH--QEIPDVCLPSGATTVYDTISHHNKL---
-TP-----EEE--PVNTLY-S----TVQIHKM---------------VRSF------TVL
---KSTPVLPHS----LYLGLHNNM-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGFSTF-IIFTSV--------FCQLTV---TA-TSG----TL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KEVVGALGGSVT
FPLNFTE-KHVETIIWN-FRSI-S----LAIK----------------------------
---------------------------AKGDVLVLQNHNKNRIVFPD---G-NY-SMKLS
QLKKSDSGVYRVEIHSSS--LQ---YPFIQEYVLYVYE--HL-SRPKVT-----MDE-QD
-KN-GTCITNLTCSMEEGGDNVTYSWK--ALGQ-E--------------------VN-EI
HDGAILPISWRLGEKDK-----TLICMARNPISHSSSTPIFVQ--NLCEDAAK-DLNSS-
-------------RVIIYIIPLL---------ITLS--FLVFVILLTMRT-EK-----RK
GSKDD------------------MERVDSH--QEKPNFCPQLEENTEYDTIPYVNGT---
-RL-----EED--AANTLY-S----IVQIPKS---------------VKSP------SSL
---PAMPHMPKP--------------LSFDN-----------------------------
------------------------------II----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQRGLWILLLC------------LQTCLE----AAR-GDTDI-LTVI

PF07686 // ENSGT00530000063114_Domain_0 (113, 263)

GTLGESVT
FPLNIQESQQVINIVWNS-E--TS----VAFVTPGD------------------------
-------------------------SETAPKVTVTHQNYNDRINVSR---Q-NY-NLEIS
NLRMEDSGIYKADINTKI--LE

ENSGT00530000063114_Linker_0_2 (263, 285)

GMVT-TTRRYNLQVFR--RL-G

PF13927 // ENSGT00530000063114_Domain_2 (285, 390)

KPKIT-----QSS-MT
SIN-STCNVTLTCSVEKEEENVTYSWS--PLGE---------------------------
-EGNAIRIFQTPDSQRL-----TYTCTAWNPVSNSS-DSISGL--QLCADAATGPRSRHT
G-----------------LL-SG----LV--MLSLFIF-VVPSFLLFLMC-RRGQ-----
----G------SYLKNFSKNSD-AISRKTIYTYVMVTRDAPPADGRIYDEIPHSK-----
-E----LPAGEE-PVSRIY-S----TLQ-TDK---------------VGKA---------
---SARDAKPPG------ISTYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFPWLLLLLLL----------Q----ENSG-DG----VDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLQESIS
LPLEIPPDEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATVMVTNPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---ISTMQQYNLHVYR-ERL-SEPQIT-----VNF-ES
SGE-GACSMSLVCSVEKAGMDMTYSWL--SRGH-S--------------------AY-TF
HEGPVLSTSWRPGDSAL-----SYTCRA-NPISNISSRPIPDG--PFCADPNYASEKPS-
--------------IAFCLLAKG-------L-LIFLLLVILAMGLWVIR----VQ-KRHK
MPRMK-------KL---MRNR-----MKL-------RKEAKPGSSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
MAYFLQRLFLFFL--FYL----------L----TESS-ASG-EDSVP-LI

PF07686 // ENSGT00530000063114_Domain_0 (111, 255)

VTGILGESVI
LPLKIPKEHQITYVAWN-SQ--RS----LATLITE-------------------------
-------------------------EG-NPPKIIINPYYKERVDFLNE-NN-IY-SPRIS
HLKMEDAGSYTAEITMAN--I---PNPIRKLFNIFIHE--RL-TKPKIM-----SDT-RI
NDN-GTCLINVTCFVEQVRENVTYNWI--PLGQ-R--------------------TN-VT
SEGHVLHIRWKPGDHD------QYTCTARNPVSNSTYT-ILAS--KLCEGFEHDKSY-IT
V-------P---------C-----------LVISTISV-IFFILGLSFWH-IQ-----RK
KKKET---------------D---------------AGDQ------KCT----TYES---
-I----SNL--N-P-AAIE-ITEYATVSHPKKNIQNNLEALNTVYVIVKNP----TMVDK
-SNTLEKKARSSGILDFGQRIGN-------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFTWLLLLLLL----------Q----EAKG-DSGD-GVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLHESIS
LPLEIPPKEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVINPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---TSTMQQYNLRVYR--RL-SEPQIT-----VNF-EI
SGE-GACNMSLVCSVEKAGMDVTYSWL--SSGD-S--------------------AY-TS
HEGPVLSTSWRPEDNAL-----SYTCRASNPVSNVSSHPIPAG--SFCADPNYASEKPS-
--------------TAFCLLAKG-------L-LVLLLLVILATVLWVIR----VQ-KRRE
MPRMK-------KL---MRNR-----MKL-------RKKAKPASSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------MA-----VSRAP----------VPD------
SARQ----IIWL---FPL------V-FCLGSG---NE-VPQ-SST

PF07686 // ENSGT00530000063114_Domain_0 (106, 271)

SP-KVVNGVRGGSAT
LLLELPAGKNASVIIWQ-QRGRESHDIAILIIQLNK------------------------
--------------------------SSSPQITRMDPERGKRLNIA----Q-SS-SLQIS
NLTMADEGLYTAQIRTNS-------RQYLFKYVLRVFE--RL-SNLVVI-----NHT-RL
FEN-GSCEIHLTCTVENPNHTASIGWQ--ASGN-I--------------------S----
LGDPNITVSWDPKNSRD----QSYTCHALNPVSKLS-VSVSAQ--SLCTGVLTNENL---
----------H-QYKEW-------------LIGLVVVI-VTICIVVCVCK-KT-------
RKRKG-------SL-SLGRRQH----LDSS--ENTD-TPGSPG-NTVYAQVTHPV--KER
EIP---KPIKN--DSMTIY-SKV----NHSRE----------------DDY------S--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGFPTHP-ILIFL--------LCQLPV--

PF07686 // ENSGT00530000063114_Domain_0 (95, 277)

-LE-ASE----EL-KELVCALGGSVT
FPLNFTI-EPVDSIVWT-FETV-T----LATIQPD-------------------------
----------------------------GDKIIVTQSRNRERMNFTS---E-NY-SLKLD
KLKKNDSGAYRVEIHSSS--SQ---NPFIQKYKLDVYE--YL-VEPKVT-----MAL-QS
NKN-GTCMTNLTCSMEQEGENVTYSWK--AQGQ-M--------------------MN-MS
YNGSFLPVSWSLEERDM-----SFICIASNPISSNFSRPIFAR--KLCEGV-TSDANVF-
-------------IFFLILLLVP---------ITLVLLVLVL-VHWRSQR-KK-----EK
EFME-------------------KKRTNSH--QKSPDFHPHTGENSEYATFSSSDKK---
-IS-----EED--PENMLY-S----TVQIPKK----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQHSLWILLVC------------LQTCLE----ATG-KDSDF-FKV

PF07686 // ENSGT00530000063114_Domain_0 (112, 255)

NGILGESVT
FPVSIQEPQQVINIAWSS-K--TS----VAFVVPKD------------------------
-------------------------AGRAPTVTVTHQNYFGRLNVSA---N-NY-NLVIS
SLRMEDAGVYQANINIQI--TASMTNTITKGYDLQVYR--RL-GKPKIT-----QSL-MT
FVN-NTCNVTLTCSEEKEEKDVTYSWS--PLGE---------------------------
-ESNLLRIFQTSEDQEL-----TYTCTAWNPVSNNS-NSISSR--QLCADLVMGHRTHHP
G-----------------LL-SV----LI--VLLLVVL-ILSSVLLFRFY-KKRQ---GS
------------LLDTFSKSSD-AVSKKIVYEYITVSRDAQSAETRIYDEISQP------
-------------------------------K---------------VGKT---------
---SSHDSKSLG------TSGYETVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLF------V-FCFGPG---NV-VSQ-SSSTP

PF07686 // ENSGT00530000063114_Domain_0 (108, 275)

-LMVNGILGESVT
LPLEFPGGEKVNSITWL-FNET-S----LAFIVPHE------------------------
--------------------------TKSPEIHVTNPKQGKRLNFT----Q-SY-SLQLS
NLKMEDTGSYRAQISTET--S-----VKLSSYTLRILR--QL-RNIQVT-----NHS-QL
FQN-RTCELHLTCSVEDADDNVSFRWE--ALGN-T--------------------L----
SSQPNLTVSWDPRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDVKI--Q----
----------Y-TDTKMILFTVS-------GICIVFGF-II--LLLLVLR-KR-------
--R-D-------SL-SLSTQRT-QGPAESA--GNLEYVSVSPTNNTVYASVTHSN--RET
EIW---TPREN--DTITIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-MAK---------------------TARMLP-----ALRSP----------APV------
PTPES---MIQLFQFLTL------V-FCLGPG---NT-VSQ-TSSAP-L

PF07686 // ENSGT00530000063114_Domain_0 (110, 270)

MVDGFLGESVT
LPLKLPAGEKIYSITWL-HNGT-S----IVFIDPND------------------------
--------------------------A---RILVTARKRKDALNVT----Q-SY-SLQLS
NLTMADTGFYKAQIGTEN--S-----SVFSCYTLRIFR--RL-RNLQVA-----NHS-QL
SVN-GTCEIHLTCTAENPNDNILLKWQ--ISGN-T--------------------S----
LNEANITISWDPKTSNE----ETYTCIAQNPISNLS-FSVSAQ--SLCKGVFNQKNQ---
----------P-LD----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLFVF-------CFGPG---NL-VSQ-SRS

PF07686 // ENSGT00530000063114_Domain_0 (106, 258)

TP-LMVNGVLGESVI
LPLEFPAGEKIQSITWL-CNGT-S----LAFIVLSE------------------------
--------------------------TNSPQIHVTHPKQRNRLNFI----Q-SY-SLKLS
NLEMEDTGSYSAQITTET--S-----AKLSSYTLRIFR--QL-RNIQVN-----NYS-QL
FQN-RTCEIHLTCSVEDADDNVSFRWE--ALGS-T--------------------L----
SSEPNITTSWDPRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDAKI--Q----
----------Y-IDTKMILFVVF-------GTCIVTGF-II--VLLLVLR-KR-------
--R-D-------SL-PLSTQRT-QGPAESA--GNIEYVSVSPVNNTVYASVTHSN--RET
EIS---TPIKN--ATVTIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVM-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ADLKRYW-----CDWAL----------GPLSENPRK
GQQQIFSPILWIPLLFLL----------M-----GLG-ASG-KETPP-TVISGMLRGSVT
FSLNISKDAEIEHIIWN-CP-PKA----LALVAY-K------------------------
-----------------------------KDIMILDKEYNGRLNVSE---D-GY-SLYMS
NLTKSDSGSYQAQINQKN--VA---LTTTKEFTLHIYE--KL-Q

PF13895 // ENSGT00530000063114_Domain_2 (285, 402)

KPQII-----VESVTP
SDT-DSCTFTLICTVKGTKDRVQYSWT--REDT-H--------------------LN-TY
NGSH-LRVSQSVCDPDL-----PYTCKAWNPVSQNSSQPVRIW--QFCT--GASRRKTAA
GKT----VVG--------ILGEP-------VTLPLVFR-ATRDTKNVVWV-FN-----MS
VISQE---------------PRGAATADSR--H----KPKGSEERRVRT----SDQDRSL
KI----SQLKME-D-AGSY--HAYVCSEASRDPSVRH--FTLLVYKRLKKP----SVTKS
-PVHRMNGICEVVLTCSVDGGGNNVTYT--------WMPLQNKA---VMSQGKSHLNVSW
ESGEHLPNFTCTAHNPVSNSSSQFSS-GTICSDPERNK---RFW--LLLP--LVLLLLMI
IGGCFILKKKKQCSSLAT-----RYRQAEVPA-EIPETPTGHGQFSVLSQRYEKLDMSAK
TTRHQPTPPSDTSSESSAT-TE---EDD----EKTRMHSTANSRNQMYDLVTHQDIAHVL
AYEGQAEYKAITPYDKVDESMDEEDMAYIQVSLNVQGETPLPQKKEDSNTIYCSVQKP-K
KTAQTPQQD-----TESPETPTYENFT------

-----------------------------CS-----VRMFP-------------------
--AQQ---LFCKL--MVL------NFPSVFIG---NT-

PF07686 // ENSGT00530000063114_Domain_0 (99, 284)

DSQ-TQAPP-LPVDGVLGESVT
LPLKFSAEEEIQSITWL-HKTA-S----VIFIPKDP------------------------
--------------------------A---QIQVTDPTRKDRLKVI----Q-SS-SLQIN
NLTMADSGRYRAQITTAT--S-----REMYNYNLAIYS--RL-RNLQVA-----NHT-QL
FEN-GSCEIQLTCSVENPNDHASFRWQ--AAGN-T--------------------I----
LEEANLTISWEPKDSSE----ETYTCIAKNPVSNLS-FSFSVQ--SLCKGVFNEKSQ---
----------L-SVILWSILVPS-------LICIVVSL-IVWKKHLWGWR-GG-----RS
LSLQS-------Q-----------FPETPR--DDPGNEPACPE-NTVYAQVTHPN--TKT
EIP---IPMKNN-DSSTIY-S----TICQPKQ--------KVKAKEPFNKP------IP-
---SRATVLDNVMNS---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MPGSPACFI-LIFL--------LCQLT-----A-

PF07686 // ENSGT00530000063114_Domain_0 (99, 277)

ASG----AL-KELTGILGGSVT
FPLTHSV-NQIDSIVWM-FNTT-T----LVTIQPKM------------------------
-------------------------ADKQDNVIVIQNHNKKRVDFSH---G-NY-SLKLS
KLNKSDSGAYRVEIYSSL--SQ---GPFIQEYELRVYE--HL-SKPKVT-----MGL-QN
NTK-P--KVTLTCSVEQGGEDVTYSHA--LW------------------------QD-EF
HNGSIFPISWKLGEKNM-----IFICMARNPISSNSSNPIFAW--KLCEGA-AGKPDSI-
-------------MVPKFLLV----------FLLLTVLVLAA-FTLIMNK-ER-----AH
ESTGE------------------KKRMDNH--QEVLNYYPSSGETSEYDTISNLNKT---
-IP-----EEN--SAKMLY-S----TVQIPTK---------------VETP------YPL
---PTSSDTPL-----F---VYANAI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MLSSTACF-TFIFL--------LCQLTG---PA-A

PF07686 // ENSGT00530000063114_Domain_0 (100, 277)

CG----VL-KKLVGALGGSVN
FPLNLSA-DPIDSIIWV-FNTT-T----LVTIQPKL------------------------
-------------------------ADKKALIIVTQHRNKERVNFPH---E-GY-SLKLS
KLKKNDSGVYRVEIHSST--LQ---DPLTQEYELRVYX--XX-XXXXXX-----XXX-XX
XXX-XXXXXXXXXXXXXXXXXXXXXXX--XXXX-X--------------------XX-XX
XXXXXXXXXX-----XX-----X--XXXXX---------XXXX--XXXXXX-XXXXXXX-
-------------XXXXXXXXVT---------PLLCFHAPVL-IILIIRR-ER-----RK
ESIEE------------------KKGLNLH--PETLNYSPTFGEASEYDTISYLNSI---
-VP-----EEN--AVNTLY-S----TVQILPK---------------VEKS------HSL
---PTLPDTPRK----F---THENVN----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VAPKSHT-----QDWAP----------GPFSSKPQR
SQLQIFSSVLWTSLLFLL----------M-----GLR-ASG-KDSAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-TVVSGILGGSVT
LPLNISVDTAIEHVIWI-GP-KKA----LAFARP-K------------------------
-----------------------------ENVTFMAKSYRGRLNITR---G-SY-SLSIS
NLTLNDAGSYKAQINQRN--FE---VTTEQEFTLFIYE--QL-QEPKVT-----MKSVKV
SEN-FSCNITLMCSVKGAEESVLYSWT--PRDP-H--------------------AS-ES
NGGSILTISRMPCEPDL-----PYTCIAQNLVSQTSSHPVHVG--QFCTDPGASRGG-KT
GET----VVG--------VLGEP-------VTLPLALP-ACRHTEKVVWL-FN-----TS
IISKE---------------REEAAMADPL--I----KSRDPYKNRVWV----SSQDCSL
KI----GQLKIE-D-AGPY--HAYVCSEASRVTSMTH--VTLLIYRRLAKP----KITWR
-LRHSKDGICRVSLTCSVKDGGNAVIYT--------WTPLQKGA---VVSQGESHLNVSW
RSGENHPNLICTASNPVSKSSHQFLS-ENICSGPERNT---NLWIGLLPV--VCLLCIGI
FS-CCIWKQKGWCSVPAF-----CSSQAEAPA-DTP--------------EYEKLDTPLR
PARQQPRPNSDSSSDSNIT-TE---EDA----DRPEVHMPISGRDEVYDQVTQEGAGHDP
APKGQADCDPVTPYVTEVESVVGENTMYAQVFFNLQGKTPVSQMEESSATIYCSIQKP-Q
TVVPPAQQDD----LEIPESPTYENFT------

------------------------------------------------------------
----MAGSPTCF-TLIYI--------LWQLTG---ST-ASG----SV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-T----LVTIQPEG------------------------
-------------------------G----PMIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFTRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCRMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICTVRNPVSSNSSSPILAR--KLCEGA-ADDSDSS-
-------------MVLLYLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESIEE------------------KKRSDIC--RETPNIRPYSGENTEYDTIPYTNRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------IENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MIWLFQSLTL------V-FCLDPG---NT-VSQ-TSSTP-LI

PF07686 // ENSGT00530000063114_Domain_0 (111, 257)

VNGTLGESVT
LPLKFPEEEKIMSITWL-HDGK-S----IIFIRPNK------------------------
--------------------------AQSPLIHVTDPKQSNRLNVT----K-SY-SLQLS
NLTMADTGSYTAQITTT---S-----VVFYSYYLRIFR--RL-GNLQVV-----TLT-ER
SRN-ETCVIHLTCSVEDPNDNVSFSWQ--VSGS-M--------------------L----
PSEANLTVSWDPKNFRD----ETYMCIAENPVSNAS-SSVSVQ--SLCKDVFH-------
------------------------------------------------------------
----------------FPAQQTQGAGAETV--RNLEYASFSSG-NTVYAQVTHAN--QER
GTL---TPLKNN-DSTTIY-T----EVHQSGE----------------VSP------WF-
---PPFLHSYLSLQTF--DLTNIGIKVSIYRCTNTSRTPKVSGH-----PQNKSEKLSCI
RITTYN------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

---------------HLHA-----YSPLAV----------------------LRWASLLY
RMGFS---FLWSLLLLGL----------L----IGPG-ASR----AP

PF07686 // ENSGT00530000063114_Domain_0 (108, 256)

-MVVTGTLGGSVT
LPLQLQDGQQVESISWV-SR--SV----PGAIATVT------------------------
----------------------LVEAGGPDTFHQEESRYWGRLSVVG---P-DR-SLQIS
HLNWADAGSYRAHINLRS--S---RLTHTREYSLHVYDTEPL-AQPRVT-----VST-RI
SGN-GHCLIILTCVAESRGGTVTYSWV--PLGP-Q--------------------TT-VS
HGGSVLSVSLRPGDSAL-----NFTCMVKNPVSNSSSLPILVP--PSCTE----------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------RPQEP----KITAS
-SQIMKDGTCFITLACLLDQAGEDVQYS--------WDPQGQGA---VVSHGGTTLSISW
RSGVSD-SYHCTVKNPVSQSSSSISI-KPLCSGSFLPCCLRKEFLL--------FLILGA
LQIKQI------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ADLKRYW-----CDWDL----------GPFSEKLRK
SQQQIFSPNLWIPLLFLL----------T-----GLG-ASG-KETSP-TVMLGTLGSSVT
FHLNISMDTEIEHVTWN-CP-PKT----LALAFY-K------------------------
-----------------------------NDIMILDKEYNGRLNVSE---D-GF-SLYMS
NLTKNDSGFYQAQINQKN--VA---LTTKKEFTLHIYE--KL-QE

PF13895 // ENSGT00530000063114_Domain_2 (286, 402)

PQVT-----VESVTP
SGT-DSCTVTLICTVKGAKDSVQYNWT--RKDT-H--------------------FN-TS
DGSPILRVSQSVCDTDL-----PYTCTVWNPVSQNSSQPVR

ENSGT00530000063114_Linker_2_3 (402, 427)

VW--QFCT--GTFRRKTAA
GKT---

PF07686 // ENSGT00530000063114_Domain_3 (427, 581)

-VVG--------TLGEP-------VTLPLVFP-ASQDTKNVVWV-FN-----TS
VISQE---------------PRGAATADPR--R----KPKGSKERRVRT----SDQDRSL
KI----SQLKME-D-AGPY--HAYVCSEASRDPSVSH--FTLLVYERLKKP----SVTQS
-PVHMMNGICKAVLTCSVDGGRNSVTYT--------WMPLQNKA---VMSQGKSHLNVSW
ESGEHLPNLTCTARNPVSNSSSQFSS-GTICSGPERNK---RLW--FLLL--LVLLLWML
IGGCFILRKKKQCPSLAT-----RYRQTEAPA-EIPETPTGHGQFSVLSQRYEKLDMSAK
TTRHQPTPTSDTSSESSTT-TE---EDD----EKTRTHSTAKGRNQVYDLVTQQDIAHDL
AYEGQAEYEAITPYDKVDESMDEEDMAYIQVSLNVQGETPLPQKKEDSNTIYCTVQKP-K
TVVL-----------------------------

------------------------------------------------------------
-----MYAFPWLLLFLLL----------Q----E-------D-DVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-EEVVAVLQESII
LPLEIPPDEEVENILWS-SH--KT----LATVVPGK------------------------
-------------------------EGHPATIMVTNPQYQGRVSLLD---P-SY-SLHIS
NLSWEDSGLYKVQVNLRS--SQ---ISIMQQYDLRVYR--RL-SKPHLT-----LKF-EI
SGE-GACNMSLTCSVEKAGMDVTYSWL--SWGD-S--------------------TY-TS
HEGPVLSTAWSPGDRAL-----FYTCRASNPISNISSRPIPAG--PFCADPDYASEKPS-
--------------TDFCLLTKG-------L-LIFLLLLILAIGIWVIQ----VW-KRCR
MPRMK-------KL---RRNR-----MKL-------RRKAKPGSSTS-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------V----------VAPKSHT-----QDWAP----------GPFSSKPQR
SQLQIFSSVLWTSLLFLL----------M-----GLR-ASG-KDSAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-TMVSGILGGSVT
LPLNISVDTAIEHVIWI-GP-KKA----LAFARP-K------------------------
-----------------------------ENVTFMAKSYWGQLNIAR---G-SY-SLSIS
NLTLNDAGSYKAQINQRN--FE---VTTEEEFTLFIYS--PFIEKVSF----------HV
IEG-DHCTLLE------GSGLESIIST--LAEP-H--------------------TC-ER
AGG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWVLLLLPL------L-LLLRPG---NT-ASQ-DSSNP-QTMNGILGESVT
LSPKLPVGEDIQSITWI-HRGR-S----LIIIMPKV------------------------
--------------------------E---QFLVTDPKWKHRLQSL----G-NY-SLRLS
NLTMEDAGLYCAQITIPT--S-----SELSCYTLKIFR--RL-SVLN

PF13927 // ENSGT00530000063114_Domain_2 (288, 390)

IT-----VHP-GL
SKT-GTCEVHLACSVENSHDA-LLKWH--GAGN-T--------------------S----
IYEANLTISWDPRNPSE----QKYTCVAENIVSSTS-SSVSIQ--SLCKGFLNQKNQ---
----------H-LDTIWII--VV-------AILMFTVI-LV---GLFVWR-KK-----GC
LCRTG-------IF-HFSTQQT-QSAAATI--RNLDYVSFSPG-NTMYACVTHPN--RQT
NTP---TPGQSG-GLSTIY-S----TVHQSKE----------------SKT------IH-
---SGKAPLDNII-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------------------MARTLT-----ILTSP----------TPF------
STAKS---MIWLFLSLLL------V-SRLGPG---NS-VSE-DS

PF07686 // ENSGT00530000063114_Domain_0 (105, 269)

SPP-LVVNGVLGESVT
LPSNFSEKENIMSITWL-HKGN-S----VIFISPKE------------------------
--------------------------A---KIQVTDPKRKDQLNVT----K-SY-SLQIN
NLTMADVGHYRAQITTST--S-----YLNTDYNLQIFR--RL-SNLQVA-----HHT-KR
SEN-NTCEIQLTCSVENPNDNVSFRWQ--VAGI-P--------------------Y----
HSETNLSISWDPKSLSE----ETYTCIAENPVSFLS-SSVSDK--SVCEGVINGKNE---
----------Y-LDIRWIIIVVA-------LTC---------------------------
------------FF-QFSTQQT-QCPAETV--SNLEYASFSSG-NTVYAQVTHSN--KET
KSS---NPVKNY-DSTTIY-S----EVNHPQE----------------RKP------IY-
---SKTTAHHNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----PGASMYLNFSILL----------C----LSAE-EAA-STE

PF07686 // ENSGT00530000063114_Domain_0 (106, 261)

VP-RMIMGTVGKSIT
LPLKMSS-NRIQTIVWL-SQ--NA----LATVD-LK------------------------
--------------------------GPEPHIIYTDSKYYKRLEVLK--NE-SY-SLRIY
NLTKEDENVYKGQITLEN--SVST-EMIIQKFFLHVYE--EL-PKPQIT-----VNF-TG
FEN-DTCNVTLLCSVKKEGKNVTYSWT--SLEDGH--------------------TV-TF
HEGPKATVSWKHGESEP-----NYICRVTNPVSSQSAQANPFP--GLCPGNPSHLSR-NL
SSI----IQKQ-------C---R-------TIIPVMLC-IVITIGVIIWK-KR-----EQ
G-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

----------SIVKEW------------------------L----------LPPGADYPR
VSQFGLVRLPLKLPPCSM----------S----AGPG-A

PF07686 // ENSGT00530000063114_Domain_0 (100, 277)

PQ-EDSAR-VVVTGTLGGSVT
LPLQWPSDLEVESISWT-TR--SV----PVAIASVT------------------------
----------------------LA-----------ENRYWGRVSVTG---P-GR-SLQIS
NLSSEDAGFYRAHIDLRR--S---PVTHTREYILQVYDTEQL-ARPRVT-----LSS-KM
SEN-QHCTFILTCVAESRGGPMTYSWT--PLGP-W--------------------TV-VS
HGGSVLSVSLRPRDREL-----TFTCMVQNPVSNSSSHPVSVP--HFCA

PF07686 // ENSGT00530000063114_Domain_3 (410, 585)

GSGTT-----V
GKT----VI-G-------TLGEP-------ATLHLELP-ARQEVENVTWS-SR-----GL
LAVLR---------------PG--PGGKPV--L--VAESQEPYTRRLSV----PYPGYSL
QI----SPLRLQ-D-SGLY--RAQITLRTPPVNITKD--FTLRVYEKLREP----NITAS
-SGIMNDGTCIITLVCSLDQAGEDVQYS--------WDPHGQRA---VVSHGGTTLSIFW
RSGDSD-SYCCTIRNPVSQRSRSILA-KPLCSAATGDA---RSWYL--------FCLITA
LL----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VAPKSHT-----QDWAP----------GPFSSKPQR
SQLQIFSSVLWTSLLFLL----------M-----GLR-ASG-KDSAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 274)

-TVVSGILGGSVT
LPLNISVDTAIEHVIWI-GP-KKA----LAFARP-K------------------------
-----------------------------ENVTFMAKSYRGRLNITR---G-SY-SLSIS
NLTLNDAGSYKAQINQRN--FE---VTTEEEFTLFIYE--QL-QEPEVT-----MKSVKV
SEN-FSCNITLMCSVKGAEKSVLYSWT--PRDP-H--------------------AS-ES
NGGSILTISRMPCEPDL-----PYTCIAQNLVSQTSSHPVHVG--QFCTDPGASRGG-KT
GET----VVG--------VLGEP-------VTLPLALP-ACRHTEKVVWL-FN-----TS
IISKE---------------REEAATADPL--I----KSRDPYKNRVWV----SSQDCSL
KI----GQLKIE-D-AGPY--HAYVCSEASRVTSMTH--VTLLIYRRLVKP----KITWR
-LRHSKDGICRVSLTCSVKDGGNAVIYT--------WTPLQKGA---VVSQGESHLNVSW
RSGENHPNLICTASNPVSNSSHQFLS-ENICSGPERNT---NLWIGLLPV--VCLLCIGI
FS-CCIWKQKGRCSVPAF-----CSSQAEAPA-DTPEPTAGHMPYSVLSQEYEKLDTPLR
PARQQPRPNSDSSSDSNIT-TE---EDA----DRPEVHKPISGREEVYDQVTQESAGHDP
APKSQADYDPVTPYVTEVECVVGENTMYAQVFFNLQGKTPVSQMEESSATIYCSIQKP-Q
V-VPPPQQND----LEIPESPTYENFT------

------------------------------------------------------------
-----MCAFPWLLLLLLL----------Q----EGSQ-RRLWRWCGS

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAILQESIS
LPLEIPPNEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVTNPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---ISTMQQYNLRVYR--RL-SEPQIT-----VNF-ES
SGE-GACSMSLVCSVEKAGMDMTYSWL--SQGD-S--------------------AY-TF
HEGPVLSTSWRPGDSAL-----SYTCRANNPISNVSSRPIPDG--PFCADPNYASEKPS-
--------------TAFCLLAKG-------L-LVFLLLVILAMGLWIIR----VQ-KRHK
MPRMK-------KL---MINR-----MKL-------RKEAKPGSSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALPWLLLLLLF----------Q----EADG-DSGD-GVET

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-KEVAAVLQESIS
LPLEIPLDEEVESIIWF-SH--RR----LATVVPGK------------------------
-------------------------GGHPGTITVTDPKYQGRVSFLE---P-TF-SLHIS
NLSWEDSGSYQAQVNLRT--SQ---IFTTQHYNLHVYR--RL-SEPHLT-----VKF-EI
SGEEGTCTMSLACSIEKAGLDVTYSWI--SWED-G--------------------TA-TA
HEGSVLSTSWRPGDKTL-----LYTCRASNPVSNASSRPIPAG--PFCADPGYPSE-AS-
--------------TSFCLLAKG-------L-LVLLLFVILAVGLWLIR----VK-TRCK
MPKMR-------KL---KRNR-----MRL-------RKKGKPDPSLA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------VAPKSHT-----QDWAP----------GPFSSKPQR
SQLQIFSSVLWTSLLFLL----------M-----GLR-ASG-KDS

PF07686 // ENSGT00530000063114_Domain_0 (106, 266)

AP-TVVSGILGGSVT
LPLNISVDTAIEHVIWI-GP-KKA----LAFARP-K------------------------
-----------------------------EHVTFMAKSYRGRL-IAR---G-SY-SLSIS
NLTLNDAGSYKAQINQRN--FE---VTTEEEFTLFIYE--QL-QEPEVT-----MKSVKV
SEN-FSCNITLMCSVKGAEKSVLYSWT--PRDP-H--------------------AS-ES
NGGSILTISRMPCEPDL-----PYTCIAQNLVSQTSSHPVHVG--QFCTDSGASRRG-KT
GET----VGG--------VLGEP-------VTLPLALP-ACRHTEKVVWL-FN-----TS
IISKE---------------RDEAATVDPL--I----KSRDPYKNRVWV----SSQDCSL
KI----SQLEIE-D-AGPH--RAYVCSEASRVTSMTR--VTLLIYRRLVKP----KITWC
-LRHSKDGICRVSLTCSMKDGGNAVMYT--------WTPLQKGA---VVSQGESHLNVSW
RSGENHPNLTCTASNPVSNSSHQFLS-ESICSGFSRNI---TKWSGVWVL--RYLICSLQ
YQ----WLAEKASSNASVR--AGWGLAANPAQ-GVPEPTAGHMLYSVLSQEYEKLDTPLR
PARQRPRPISDSSSDSNIT-TE---EDT----DRPEVHKPINGRDQVYDQVTQEGAGHDP
APKGQADYDPVTPYVTEVESVVGENTVYAQVFFNLRGKTPVSQMEESSATIYCSIQKP-Q
TVVPPPQQND----LEIPESPTYENFT------

------------------------------------------------------------
-----MAVLLWLLPLLLL----------L----EAKG-DSGD-DVNP

PF07686 // ENSGT00530000063114_Domain_0 (108, 257)

-EEVAAVLQGPAS
LSLEIPSDEDVERIIWY-FH--KP----LATVVPGK------------------------
-------------------------DGHPATIRVTNPQFENRLSWLD---T-SH-TLLIR
NLSWADSGLYQAQVYLGT--SQ---LSTMQYYDLRIYQ--WL-SEPQIT-----VNF-EI
SRE-GPCNMSLTCFV-KADMDVTYSWF--SSGD-S--------------------TD-TN
HEGPVLRTSWRPGDSAL-----LYTCRASNPISSIRSRPISAG--HFCADPGYS-EKPS-
--------------TPFCLLAKG-------L-LLLLLLVILAVGLWVVRV-VRVQ-KKKQ
MPKMK-------KL---KRNR-----MEL-------RKREKPGLSLP-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLF------V-FCFGPG---NV-VSQ-SSS

PF07686 // ENSGT00530000063114_Domain_0 (106, 275)

TP-LVVNGILGESVT
LPLEFPAGEKVNSITWL-FNET-S----LAFIVPHE------------------------
--------------------------TKSPEIHVTNPKQGKRLNFT----Q-SY-SLQLS
NLKMEDTGSYRAQIATET--S-----VKLSSYTLRILR--QL-RNIQVT-----NHS-QL
FQN-RTCELHLTCSVEDADDNVSFRWE--ALGN-T--------------------L----
SSQPNLTVSWDPRISSE----QDYTCIAENAVSNLS-FSLSAQ--KLCGDVKI--Q----
----------Y-TDTKMILFTVS-------GICIVFGF-II--LLLLVLR-KR-------
--R-D-------SL-SLSTQRT-QGPE-SA--GSLEYVSVSPTNNTVYASVTHSN--RET
EIW---TPREN--DTITIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----VPRFSQSI-LT

PF07686 // ENSGT00530000063114_Domain_0 (76, 277)

SMP--------VCESTG---PA-TSG----AL-KELVGDLGGSVI
FPLKLPR-IQIDSLVWI-FNTT-P----LITIQPKT------------------------
-------------------------PDRQPNVIVTQSHNKERVDFLL---G-NY-SLKLS
KLDKSDSGDYRVVIYSSS--LK---DPFIQQYELRVYE--HL-SKPKVT-----MGL-QN
NEN-GTCVTNLTCFMDQGGEDVTYSWE--SLGQ-A--------------------AN-ES
HNGSILPISWRLGKKGM-----TFICVARNPISSNSSNPVFAW--KLCEGA-ADDSESS-
-------------VVLYILGV-I---------FLLSAFALVP-VILITRK-ER---KEE-
-SIEE------------------KKGMDTH--QEILNNC-PSGETPVYDTITCVNNT---
-IP-----EEN--PVNTLY-S----SVQIPQK---------------MEKP------HSP
---PTSPNMPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCF-TLIYI--------LWQLTG---ST-

PF07686 // ENSGT00530000063114_Domain_0 (99, 276)

ASG----SV-KELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-P----LVTIQPEG------------------------
-------------------------G----AMIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFTRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCRMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICIVRNPVSSNFSSPILAR--KLCEGA-ADDSDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESVEE------------------KKRADIC--RETPNICPYSGENTEYDTIPYTDRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------MENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQHHVWILLLC------------LQTWPE----AAG-EDSEI-FTVFGILGESVT
FPVNIQEPQQVKIIAW

PF00047 // ENSGT00530000063114_Domain_0 (137, 267)

TS-E--TS----VAFVKPGD------------------------
-------------------------SETAPTVTVTHRNYYDRIHVLD---P-SC-NLIIS
NLRMEDAGNYKADINTET--A---PYTITKHYNLQVYR--RL-GKPKIT-----QSL-MT
SVN-STCNVTLTCSVEKEEKNVTYRWS--PLGK---------------------------
-EGNVLQIFQTPKDQEL-----TYTCTAQNPVSNNS-DSISAQ--QLCADIPMSFRTHHT
S-----------------LL-SM----LA--IFFLLVL-ILSSVFLFRLY-KRRQ-----
----D------------------AASKKTTYTYVTASKDTQPAESRIYDEILQSK-----
-V----LPSKEE-LVNTVY-S----EVQLSDK---------------MGKA---------
---GTQNSKPPG------PSSYEIVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MRALLWLLLLVLS----------Q----EAAE-GYSGDGA

PF07686 // ENSGT00530000063114_Domain_0 (106, 261)

DP-EEVVGILHESIS
LPLEMPFDEEVENIIWS-SH--KR----LATVVPEK------------------------
-------------------------EGHPATIMVTDPRYDGRVSFLE---P-TY-SLHIQ
NLSWEDSGSYQAQVNLRT--SQ---VSTMQQYNLRVYQ--HL-SQPHMT-----VKF-EI
PGEEGACNISLICSVENAGLDVTYTWI--SWED-G--------------------AD-AA
HEGAILRAFWRPGDKAV-----SYTCRASNPVSNITSRPIQAG--SFCADPGYPLEKAS-
--------------TSFCLLAKG-------L-LILLLFGTLAMGFWFIR----VQ-TRGK
VLRMK-------KL---KRDR-----MKL-------RRKGRPGPSLS-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQHHLWILLLC------------LQT-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------C--RL-G

PF13927 // ENSGT00530000063114_Domain_2 (285, 390)

KPKIT-----QSL-MT
SVN-STCNVTLTCSVDKEEKNVTYSWS--PLGK---------------------------
-EGNVLQIFQTPEDHEL-----TYTCTAWNPVSNNS-ESISAQ--RLCTDTTMGFRTHHT
R-----------------LL-TM----LA--GFFLISL-ILSSVFLFHLC-KRRQ-----
---------------------D-AVSKKTIYTYITVSRDAQPAESRIYDEIPQSK-----
-V----PPSKEE-PANTVY-S----ILQFSDK---------------MGKT---------
---STQDSKPLG------TSSYEIVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ANVKRYL-----CGWSL----------EPFSDKPLK
RQPEVFSSVLCVPLLFLL----------M-----GQG-ASE-KETPP

PF07686 // ENSGT00530000063114_Domain_0 (108, 258)

-IVISGMLGGSVT
FPLNISGDAEIESVAWS-YP-PKS----LAIAFS-P------------------------
-----------------------------KHVYIVDKDYSGRLNVSN-----TY-SMRIS
NLTKNDSGSYQAQINQK

ENSGT00530000063114_Linker_0_2 (258, 306)

N--SD---LTRVEKFILGIYE--QL-QEPQVT-----MTSVTT
SEN-G

PF13895 // ENSGT00530000063114_Domain_2 (306, 402)

SCTITLICTVNGGKDGVQYSWT--QKDT-D--------------------FN-ES
HRDPILTVSQSICDPGL-----PYTCTARNPVSQNSSQPVRVW--QFCT--GASRGK-TV
GET----VVG--------ILGEP-------MTLSLAFL-DSQDTNNAVWV-FN-----KS
VISQE---------------WEGAETADPH--R----KPNGPKEKKVWV----SGQDHSL
KI----SQLEME-D-AGTY--YAYVCSVASRDAIVRY--FTLLIYQRLKKP----SVNQS
-HVHRKDGICKVQLTCSVEDGGNNVTYT--------WTVLPKEA---AVSQVESLLNISW
KCGERPPNFTCTAHNPVSNSSSQFSL-GAISSGFERNL---KFCIWLMAL--ILCSLVML
VVWC-ILKQKKQCKFSSLTLPTLRKRCVNPAQ-CVLETPAGHMRYSVLSQRYEKLDMPAE
TTRPKP--TSDTSSDSSAT-IEEDEEDE----GKTRMHSSVDGGSEAYDLDTQGDSAREL
ASERQAEHEVLVPDDTVVKSEGEEDTAYIQVYLNVQGKIPVPQKKESPNTIYCSVQKP-K
KVRTIFFFLNLLMLNGSLNGRIYH---------

------------------------------------------------------------
----MAASPTRL-MLISL--------LCQLTV---SA-TSE----AL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KELVGAVGGSVI
FSLNFTV-KQVDSISWL-FNETTT----LVTVQPAI------------------------
-------------------------GEEQITFIVAQKRNKPRVHFQD---G-GY-SLTFS
QLKKTDSGIYSVMIHSSD--SQ---SLLPMKYRLHVYE--HL-SKPKVT-----MGL-YS
NKN-GTCITNLTCSMEEGGEDVTYSWK--ILEQ-A--------------------AN-ES
HDGSILPISWTLGENDV-----TFICTARNPISNNSSSPILAQ--KLCRGA-TGDSGFP-
-------------PILLYILLAS---------ILLCLLVPVA-FLLIKRT-KR-----RK
EPVES------------------KSGMDIH--QEIPHSYPYFAENTEYDTIPYIHKN---
-DP-----VED--PANTLY-S----TVQIPKK---------------VENP------HSS
---SRMPDTPRL----S---S---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------ASPRRHT-----DDWAP----------QPFSNKPPK
SQPHVFSPYLWTLLLFLL----------L-----GQG-ASE-KDSAS

PF07686 // ENSGT00530000063114_Domain_0 (108, 257)

-TVVKAIVGGSVI
LSLNISVDAEIEQITWS-GP-KDA----LVLAFP-S------------------------
-----------------------------GEILFLDKSYKGRINIP----K-NN-SLSIN
KLTLKDAGSYKARINQKG--SE---D-FNERFILYIYE--QL-QEPQVT-----IQSVNV
SEN-ASCTITLVCSVEGAGGDIQYKWT--SRDP-H--------------------AS-ES
WGHPTLTISWLPCDADL-----PYTCTAKNPVSQSSSHPVHVS--QFCTDLGASRGG-PM
GKT----VLG--------VLGES-------ITLSLALL-DSQHIDNVVWI-FN-----TS
IISKE---------------WREEATANQL--I----EFKDPDQNTVWV----SSQDYSL
KI----VQLKME-H-AGLY--QAYLCSNARVA-SVKH--INLRIYR--------------
------------------------------------------------------------
---------------------------------PERST---EFWIGLSLVVLFILLSLGI
SG-WCFWKQQRQWSAPAFS-----SSQAET---------------SVDTPGYEKLDTFPK
TA----RHASDSSSDSNGT-TE---EDE----ERTGMHQPVNGRDQVCDSVTREDAGLDS
DSEGQPEYDQVTPDNMAPALAVEGETVYTQVFLHLPGKTPVPQKKENSATVYCSIQKP-Q
KVVPPSQQND----LKSPEIPTYENVP------

------------------------------------------------------------
-----MCAFTWLLLLLLL----------Q----EAKG-DSGD-GVDL-E

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

EVVAVLHESIS
LPLEIPPKEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVTNPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---TSIMQQYNLRVYR--RL-SEPQIT-----VNF-EI
SGE-GACNMSLVCSVEKGGMNVTYSWL--SSGN-S--------------------AY-TS
HEGPVLSTSWRPGDSAL-----SYTCRASNPISNVSSRPISAG--SFCADPSYASEKPS-
--------------TAFCLLAKG-------L-LVLLLLVILATVLWVIR----VQ-KRRK
MPRMK-------KL---MRNR-----MKL-------RKKAKPASSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGFSTF-IIFTSV--------LCQLPV---TA-TSG----PL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KEVVGALGGSVT
FTVSFPE-KQIDTVIWT-FNTF-T----VAIV----------------------------
---------------------------NKDNAKVLQNPKKEKILFPD---G-SY-SMKLS
QLKKNDSGVYRAEIHSTS--LQ---SPFTQEYVLYVYE--TL-SAPKVT-----TDE-QP
SKN-GSCTTKLTCSVEEEGDNVTYSWK--AIGQ-G--------------------AH-EL
HDGAILPISWKLGEKEK-----TLICMARNPISHSSSNPVLAR--NLCEDTANLDKSSP-
-------------RFILYTLPVA---------IVFS--LT-LIIAFAVRT-EK-----GK
GSKKD------------------TERVDN--------FCP-LEENTEYATIPYINER---
-SL-----EDD--AANTLY-S----TVQIPKA---------------VRTV------KAD
---SHLNCRSLS----A---PV-QVHISL-------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCL-TLIYI--------LWQLTG---SA-ASG----PV-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

RELVGSVGGAVT
FPLKSKV-KQVDSIVWT-FNTT-P----LVTIQPEG------------------------
-------------------------G----TIIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYYVGIYSSS--LQ---QPSTQKYVLHVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCCMEHGEEDVIYTWK--ALGQ-A--------------------AN-ES
HNGSILPISWRWGESDM-----TFICVARNPVSSNFSSPILAR--KLCEGA-ADDPDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ER-----QE
ESIEE------------------KKRADIC--RETPNICPHSGENTEYDTIPHTNRT---
-IL-----KED--PANTVY-S----TVEIPKK---------------MENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------MV-----VSRTP----------APD------
SAGQM---MVWL---FPL------V-FCLGSG---NE-VSQ-SNE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

SP-KVVNGVLGGSAT
LLLELPTGKEANLIIWN-HEGEASQVTTILIIQLNK------------------------
--------------------------SGTPQIIHSDLKMRERLSIT----Q-SY-FLQIN
NLTMADAGLYRAQINTKD--S----KQDFSIFTLRVFE--RL-SNLEVT-----NHT-RL
FEN-GTCEIHLTCIVENPNHTVSVGWQ--ASGG-I--------------------S----
LGEPNLTVSWDPKNSSD----QSYTCQAENAVSNLS-VSVSAQ--SLCKGVLPKENL---
----------Q-WQQTY-----I-------IIGTLLVI-VIVCLFICFWK-K--------
--RTG-------KF-S-F---S----IDSS--QNTD-APGSPGSNTVYAQVTHPV--QEM
EIP---KSTKN--DSMTIY-S----IVNHSRE----------------VNP---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFTWLLLLLLL----------Q----EAKG-DSGD-GV

PF07686 // ENSGT00530000063114_Domain_0 (106, 257)

DP-EEVVAVLHESIS
LPLEIPPKEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVINPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---TSTMQQYNLRVYR--RL-SEPQIT-----VNF-EI
SGE-GACNMSLVCSVEKAGMDVTYSWL--SSGD-S--------------------AY-TS
HEGPVLSRSWRPGDNAL-----SYTCRASNPVSNVSSHPIPAG--SFCADPNYASEKPS-
--------------TAFCLLAKG-------L-LVLLLLVILATVLWVIR----VQ-KRRK
MPRMK-------KL---MRNR-----MKL-------RKKAKPVSSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALLWSLLL-LL----------Q----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVVGVLQESIN
LSLEIPSNEEIKHIDWL-FQ--NN----IAIVKPGK------------------------
-------------------------KGQPAVIMAVDPRYRGRVSISE---S-SY-SLHIS
NLTWEDSGLYNAQVNLKT--SE---SHITKSYHLRVYR--RL-SKPHIT-----VNS-NI
SEE-GVCNISLTCSIERAGMDVTYIWL--SSQD-S--------------------TN-TS
HEGSVLSTSWRPGDKAP-----SYTCRVSNPISNISSRRISVG--SFCADPGYL-EKP--
--------------SMLCLLVKS-------L-FLLLLLAILTVGLCLFR----AQ-KSYE
TPRVR-------KL---KRNR-----IKL-------RKKGKSGPTPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MLAYLACF-I-LVL--------LCQHPG---PA-TSG----AP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-KELVGNLGGSVT
FPLKLPG-IQIDTIVWT-FNTT-P----LVTIEPKM------------------------
-------------------------PDRQANVIVTHSRNKERVKFLQ---G-NY-SLKLS
KLSKNDSGDYRMVIYSSS--LK---DSFSQEYRLRVYE--HL-SKPKVT-----MGL-QN
NKN-GTCLTNLTCFMDQGGEDVTYSWE--SLGQ-A--------------------AN-ES
HNGSILPISWRLGERDT-----IFICVVRNPISSNSSNPIFAW--KLCEGA-AADSESS-
-------------MILASLGVLL----------LIIAFALMP-VLLIMQR-EK---RKE-
-SIEE------------------RKRMDTH--QEIPNYYPPSGETPVYDIITCVDKT---
-IP-----EEN--PEKTLY-F----SVQIPQK---------------MEEP------DST
---PISPDTPTL----F---TYEIVN----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MLGAPACFI---FL--------LCQLTG---PA-ASG----IP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-KKLVGAIGGSVI
FPLNLSV-NLVDSIIWV-FNST-T----LVTIQPKT------------------------
-------------------------AGKKALVIVTQKRNLERVNFPH---E-GY-SLKLS
RLKKNDSGIYRVEIHSST--LQ---DPLTQEYELHVYE--YL-SKPKVV-----IGL-QE
NKN-GTCVTNLTCSMEHGEEDVTYSWK--SLDQ-T--------------------TN-ES
HRGSILPISWRWEKSDM-----TFICMASNPISSNSSNPIFAQ--NLCEGA-AGGQAPY-
-------------VVLYVLLS----------FFLLCSLALVL-IIFIIQR-ER---KK--
EIIEE------------------KKELDTH--QKTLPFPPIPEEMPEYDTISTFNGT---
-IP-----EEN--PANTIY-S----TVHIAPK---------------VTEP------YSL
---PMLSDTPTA----S---IYNNVM----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----------M-VRSHH--------FSVSTV---TV-AFG----TL-KELAGAIDGSV

PF07686 // ENSGT00530000063114_Domain_0 (120, 276)

T
FTLNITV-KQVDSIVWT-FKTL------------SL------------------------
-------------------------NRKQDNVIVAQNRNKERIAFSE---G-DY-SLKLS
QLKKNDSGVYRVEIYSTS--SQ---SPFTQEYVLHVYE--YL-SKPKVT-----RGL-QN
NKN-GTCITNLTCSIEQGGENVTYSWR--VMGQ-A--------------------AN-ES
HDGSFLPISWRLGETDM-----TFICTARNPISNSSSSPILSW--ELCEGDCLLFPGAS-
-------------GWNDYAFFSHDPYGILWNQRLLGNHQAG--RKVEEKR-KG-----KE
YPIED------------------RKRVDIH--QETPNFCPHFGENTEYDTVPYTNKR---
-NP-----VED--AANTLY-S----TVQIPKV---------------VKSP------SNL
---PATPDTSRS----L---SFENVL----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALLWSLLL-LL----------Q----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 266)

DP-EEVAGVLQESIN
LSLEIPSNEEIKHITWH-FQ--NN----LATVKPGK------------------------
-------------------------NGQPAIIMAVDPRYRGRVSISE---S-SY-SLHIS
NLTWEDSGLYDAQVNLKT--FQ---SHITMSYHLRVYR--RL-SKPHIT-----VNS-NI
SEE-GVCNISLMCSIERAGMDVTYIWL--SSQD-S--------------------TN-TS
HEGSVLSTSWRPGDKAP-----SYTCRVSNPVSNISSRRISVG--SLCADPGYP-EKP--
--------------SMLCFLVKS-------L-SLLLLLAILTVGLCIFR----AQ-KNYE
MPRVR-------KL---KRNC-----IKL-------RKRGKSGPTPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQHHVWILLLC------------LQTWPE----AAG-EDSEI-FTVFGILGESVT
FPVNIQEPQQVKIIAWTS-E--TS----VAVVNPGD------------------------
-------------------------SETAPTVTVTHRNYYDRIHVSD---P-SC-NLIIS
NLRMEDTGDYKADINTET--A---PFTITKRYNLQVYR--RL-G

PF13927 // ENSGT00530000063114_Domain_2 (285, 390)

KPKIT-----QSL-MT
SVN-STCNVTLTCSVEKEEKNVTYRWS--PLGK---------------------------
-EGNVLQISQTPQDQEL-----TYTCTAQNPVSNNS-DSISAQ--ELCADIPMSFRTHHT
S-----------------LL-SV----LA--VFFLLVL-ILSSVFSFRLY-KRRQ-----
----D------------------AASKKTTYTYVTASRYTQPAESRIYDEILQSK-----
-V----LPSREE-LVNTVY-S----EVQLSDK---------------MGKA---------
---STQDSKPPG------TSSYEIVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCL-TLIYI--------LWQLTG---SA-ASG----PV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSVGGAVT
FPLKSKV-KQVDSIVWT-FNTT-P----LVTIQPEG------------------------
-------------------------G----TIIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYYVGIYSSS--LQ---QPSTQEYVLHVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCCIEHGEEDVIYTWK--ALGQ-A--------------------AN-ES
HNGSILPISWRWGESDM-----TFICVARNPVSSNFSSPILAR--KLCEGA-ADDPDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ER-----QE
ESIEE------------------KKRADIC--RETPNICPHSGGNTEYDTIPHTNRT---
-IL-----KED--PANTVY-S----TVEIPKK---------------MENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGFSTF-IIFTSV--------LCQLPV---TA-TSG----PL-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KEVVGALGGSVT
FTVSFPE-KQIDTVIWT-FNTF-T----VAIV----------------------------
---------------------------NKDNAKVLQNPKKEKILFPD---G-SY-SMKLS
QLKKNDSGVYRAEIHSTS--LQ---SPFTQEYVLYVYE--TL-SAPKVT-----TDE-QP
SKN-GSCTTKLTCSVEEEGDNVTYSWK--AIGQ-G--------------------AH-EL
HDGAILPISWKLGEKEK-----TLICMARNPISHSSSNPVLAR--NLCEDTANLDKSSP-
-------------RFILYTLPVA---------IVFS--LT-LIIAFAVRT-EK-----GK
GSKKD------------------TERVDN--------FCP-LEENTEYATIPYINER---
-SL-----EDD--AANTLY-S----TVQIPKA---------------VKSP------SYL
---PA------E----P---PM-WRQLSFEN-----------------------------
------------------------------II----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFTWLLLLLLL----------Q----EAKG-DSGD-GVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLHESIS
LPLEIPL-EEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVINPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---TSTMQQYNLHVYR--RL-SEPQIT-----VNF-EI
SGE-GACNMSLVCSVEKAGMDVTYSWL--SSGD-S--------------------AY-TS
HEGPVLSTSWRPEDNAL-----SYTCRASNPVSNVSSHPIPAG--SFCADPNYASEKPS-
--------------TAFCLLAKG-------L-LVLLLLVILATVLWVIR----AQ-KRRE
MPRMK-------KL---MRNR-----MKL-------RKKAKPASSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MQALPWLFLLLLL----------Q----EAKG-NSGD-EMDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 267)

-EEVVAVLQESII
LPLEILSDEEVEDIIWS-SR--VR----LATVVPEK------------------------
-------------------------EGNPPTISVTNTRYQGRVSFLG---P-SY-ALQIS
NLSSEDSGPYQVQVNLRT--SQ---LSIIQHYNLRVYR--RL-SEPRVA-----VKF-EI
SRE-DACNISLTCSVEKSGKDVTYSWI--SWGD-S--------------------DD-AI
HEGPDFSTSWRPGDNAL-----SYTCRVSNPISNVSSRPILAG--PFCADPSFPLEKAS-
--------------SSFCLLVKV-------L-LLLLLLIILAVGLWVVR----VQ-TRCK
TPRMK-------KI---RRNR-----MKL-------RKKGKPGPSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCL-TLLYI--------LWQLTG---SA-AHE----VM-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KELVGPLGGAVT
FPLTSKV-NQVDSIVWT-FNTT-L----LVTMQPEM------------------------
-------------------------G----TIIVTQNRNKERISFLN---G-TY-SLKLS
ELKKNDSGVYHVKIYSSS--HH---DPFTQEYVLHVYE--HL-SRPKVT-----MGL-QS
NEN-GTCVTNLTCYMEHGGEDVIYTWK--ALGE-A--------------------AS-ET
HNGSILPISWRWGESDV-----TFICFARNPISSNSSSPILAR--KLCEGA-AGDPNPS-
-------------MILLCLLLVP---------SLLTLIALGL-LLWFIRR-ER-----QE
ESIEE------------------KKRTDIR--QETPNLCPHSGENTEYDTISYTNRT---
-IP-----MED--PANTVY-S----TVEIPKK---------------MESP------HSL
---LTMPDTPRL----F---TYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAQHRLGILLLC------------LQTCLE----VSG-SNTDI-IT

PF07686 // ENSGT00530000063114_Domain_0 (111, 258)

VNGILGESVT
FPLNIQGSQQVNSIAWTS-K--SS----VASIIPGN------------------------
-------------------------SGTPPIITVTHQDYYERINVSG---Q-NY-NLEIR
NLRMEDAGTYKADISLKT--SEKKITTTTKHFKLQVYR--RL-GKPKIT-----QSL-MT
SMN-NTCNVTLTCSVEKEEKNVTYTWS--PLGE---------------------------
-EGNVLQIFRTPVNQEL-----TYTCTVWNPVSNNS-DSISAR--QLCTDVAMGLHTRRT
G-----------------LL-SG----LA--VLSLFML-ILPAVLLFLFC-KRRQ---GR
IFPE-----------------D-AVSKNTIYTYITASRNTQQAESRIYDEIPQSK-----
-V----FPAKEE-PVNSIY-S----VVQCSDK---------------V------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----------------------------------SPS-GPL-GAAAP

PF07686 // ENSGT00530000063114_Domain_0 (108, 257)

-QELNGAIGGSVT
FPLDIQAVWQVKSVFWT-SK--GA----IATVIPEG------------------------
-------------------------PGNPPQIIAYTQQYKGRLIVA----A-NY-DLTIG
NLSLEDAGTYRADVSIAQ--TT-----NTTQFSLRIWD--LL-TEPSVMVNSMMVNS-TA
SDN-GHCNVTLTCSVARGGDNVTFSWM--PLGP-E--------------------TS-VS
PYDYVLSIAWRPGDPPQ-----DYTCTATNPISNSSHTIPADR--IHCPGINFQ----GA
S---------------------------------------------------L-----SG
EPEDG----------PTHQKV---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
------------LTFILW--------FSVSAG---PA-

PF07686 // ENSGT00530000063114_Domain_0 (99, 277)

ASG----AQ-QELVGAVGGSVT
FPLTHSV-DRIDSIIWI-FKST-T----LITIQPTT------------------------
-------------------------TNKPDTVIVTKNHDKGRVGFLH---G-NY-SLKLS
KLSKNDSGAYSVQIHSSS--LQ---EPFTQEYGLRVYE--HL-SKPKIT-----LGL-KS
NKN-GTCVTNLTCFLERGGEDVTYSWK--TLGK-T--------------------SN-ES
HNGSVLPITWTLREKDM-----TFICMARNPISSNSSNLIFAR--KLCEGI-AGDLDST-
-------------MGLWISSLLI-------------VLVLVL-IILTMWK-QSLGSNEGN
QKSTE------------------EKKMDTH--PEIPNCYPPSGETAEYDTISNPNKT---
-IP-----EEN--SEHPLY-C----TVQIPQK---------------MEKP------HSL
---PTSPDTPKL----F---IYEKVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
---------------------------------PAAG-AFG-EESGP-TRLNGAQGESVT
FALVVPRGSRVDSVAWN-GK--SI----IAIVTP--------------------------
--------------------------GEPAPLRVIHTHYRDRLRVPD---G-SY-SLQVT
DLRPEDTGTYTAQIATQG--SP---DPIFRRFALRVYK--RL-AESDITVT-PVLGS-VN
TVN-GTCSITLNCTVQGAGEDVNCTWN--QTEA-G--------------------T--VI
STGASIHISHRLGDEGA-----SVTCTARNPVSSSSRSVSLQ---DVCAEPPGC------
-----------REM

PF11465 // ENSGT00530000063114_Domain_3 (435, 585)

DVAAIAGES-------VQLQ-PVT-WPESWVKISWE-VT-----LD
SG-E--------TYRLLTANKGEAPHLRSV--L--HFA-----SRVTLH-----PENLSL
QI----DPVNKS-D-RGLY--ALEITAAGGR---VDRTTFRVSVFERVRQP----NLTVL
-SAHTQHGQCNLTLSCSVPGA-DAVTYS--------WS----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--FCSPELCIFLVLPILW----------F----TGSW-Q---SV

PF07686 // ENSGT00530000063114_Domain_0 (105, 273)

YSA-RNVVGVVGESVN
LSFSKLYPGPYSEISWF-YN--ET----QKILLWER------------------------
-------------------------EE---QTKIFETNLKPRICLA---GD-NI-TLHIQ
QLRKEDSSTYKLQTSLLS--T---RQVLSEHIRLDVYE--RL-TKPQIA-----LSP-SS
SDN-GTCLFNATCSVEQVRENVTYNWI--PLGQ-R--------------------IN-AS
IEGPILSVRWKPGDQD------QYTCIARNPVSNSSYT-IFAS--KLCAGVEYDKSH-NR
L-------L---------Y-----------LMLVTILV-ILFMLRL--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCV-TLMYI--------LWQLTG---SA-ASE----AM-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KELVGPLGGAVT
FPLVSNV-KQVDSIVWT-FNTT-P----LVTMQPEA------------------------
-------------------------G----TIIVTQNRNKERVSFLN---G-SY-SLKLS
ELKKNDSGVYHVEIYSSS--LQ---DPFTQDYMLHVYE--HL-SRPKVT-----MGL-QS
NKN-GTCVTNLTCYMEHGGEDVIYTWK--ALGQ-A--------------------AS-ET
HNGSILPISWRWGESDM-----TFICFARNPISSNSSSPILAR--KLCEGA-AGDPNPS-
-------------TILLCLLLVP---------SLLTLFALGL-FIWFIRR-ER-----QE
ESIEE------------------KKRTDIR--PETPNLCPHSGENTEYDTISYPNRT---
-IP-----MED--PANTLY-S----TVEIPKK---------------IESP------HSL
---LMMPDTPRL----F---TYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFPWLLLLLLL----------Q----EGSQ-RRLWRWCGS

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLQESIS
LPLEIPPDEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATVMVTNPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---ISTMQQYNLHVYR--RL-SEPQIT-----VNF-ES
SGE-GACSMSLVCSVEKAGMDMTYSWL--SRGH-S--------------------AY-TF
HEGPVLSTSWRPGDSAL-----SYTCRANNPISNVSSRPIPDG--PFCADPNYASEKPS-
--------------IAFCLLAKG-------L-LIFLLLVILAMGLWVIR----VQ-KRHK
MPRMK-------KL---MRNR-----MKL-------RKEAKPGSSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------AGTKSHT-----NDRNL----------GPFYSNPQK
SWPQIFSSTLWTFLLFLL----------M-----GLR-VSG-KDS

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

SP-KVVFGILGGSVT
LPLNISVDAEIEHVTWN-GP-QNA----LALAYP-N------------------------
-----------------------------REVTIMVKSYQGRLNITS---S-SY-SLNIS
NLTMKDAGSYKAQINQKD--SK---DTTEEKFTLHIYA--QL-PEPQVT-----MESVNM
SEN-SSCDITLKCSVKGEGKDVLYSWT--PRDT-H--------------------AS-ES
NGGSILTISQTPCDPDP-----PYTCTARNPVSQSSSHPVHAW--QFCSDPETFRGR-AM
GEP----VMG--------ILGES-------ITLPLALSV-SQGTGNVIWM-FN-----TS
VISKE---------------CE--ATANPL--M----KFRDLDKNRVWI----SGQDYSL
KI----DQLKLE-D-AGLY--HAFVCSEASRVISMTH--VTLLIYRRLVKP----KITWK
-LGPTKDGTCRVSLTCSVEDGGNNVTYT--------WTPLQKGA---IVSQGGSHLNISW
RSDENRPNLTCTASNTVSNSSHQFPS-GNICSGPEGNM---RLWTVLSLM--VCLLCFGV
FG-LCIWKQKRQRSDPVFS-----SSQAEASA-DTPEPAASRTLYTVFSQGYEKLDIPSK
PARQQPPATSDSSSDSNVT-TE---EDE----ERPEMPKTINGRDEVYDLVTQEDTECDS
ASEGQ-EYDLVTPDDTVVKPMVEGDTEYTQVFFNLQGKIPVSQKKESSVTIYCSVQKP-Q
V-MPPPQENE----RESPEIPTYENFI------

------------------------------------------------------------
----MLGVPACFI---FL--------LCQLAG---PA-ASG----IP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-KKLVGAIGGSVI
FPLNLSV-NLVDSIIWV-FNST-T----LVTIQPKT------------------------
-------------------------ADKNALIIVTQKRNTERVNFTH---E-GY-SLKLS
RLTKNDSGVYRVEIHNST--LQ---DPLTQEYELHVYE--YL-SKPKVI-----IGL-QE
NKN-GTCVTNLTCSMEHGEEDVTYSWK--SLDQ-A--------------------TN-ES
HRGSILPISWRWEKSDM-----TFICMASNPISSNSSNPIFAQ--NLCEGA-AGGQTPY-
-------------VILYVLLS----------FFLLCSLTLVL-IIFIIRR-ER---KKVS
EIIEE------------------KKELDTH--QETLHFPPISEEMPEYDTISNFNSV---
-IP-----EEN--PANTIY-S----TLHIPPK---------------VTEP------HSL
---PMSSDTPRS----C---TYNNVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----PSRGLPSCLELASQ----------I----AAKG-DSGD-DVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLHESIY
LPLEIPSDEEVEDIIWY-SH--KR----LAIVVPEK------------------------
-------------------------EGRPANITVTDPHYRGRVSFLE---P-SY-SLYIS
NLSWEDAGLYQARVNLGT--SQ---IFATRDYDLRVYQ--RL-SELQIT-----VNF-EI
SGE-RTCNMSLTCSVEKAGMDVTYSWL--SWGD-N--------------------TD-TV
HEGPVLSASWRPGDSAP-----SYTCRASNPVSNASSHPIPAG--SFCADPGYPSEKPS-
--------------TAFCLLAKG-------L-LFLFLLVILAVGLWVIR----VW-KRDK
MPRMK-------KL---RRNR-----MKL-------KKRRTPGPSPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALLWSLLL-LL----------Q----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVVAALQESIS
LSLEIPSNEEVKDIIWF-SQ--KN----LVTVVPGK------------------------
-------------------------EGTPAVIIVMDPRYQGRVGISE---S-SY-SLHIS
NLTWEDSGLYQAKVSLNT--SQ---LSITKSYDLRVYR--RL-SKPHIT-----VNF-RI
SEE-GACNISLMCSVERAGMDVTYTWL--SPQD-S--------------------AN-MS
HEDAIISTSWRPGDRAL-----SYICRASNPVSNSSSHLIPVG--SFCADPGSP-EKP--
--------------SMSCLLAKG-------L-ILLFLLVILAVVLCVFQ----AR-KNYE
MSRVR-------KL---KRNR-----IKL-------RKKGKLGPSLD-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTGL-IHVFL--------LCQFTA---SA-TSG----AM-

PF07686 // ENSGT00530000063114_Domain_0 (109, 276)

KELVGAIGGSVT
FPLTFTE-KQIDSIVWS-FNRT-T----LITIQPGT------------------------
-------------------------ESKNATVIVTSNRNRERVDFSG---G-GY-SLKLN
KLRKNDSGSYSVQIHSSS--SQ---FPSTQEYMLHVYE--QV-SKPKVT-----VGL-QS
NKN-GTCMTNLTCYMEREEEDVTYSWE--TLGQ-T--------------------VP-EF
HNGPILSVSWRMGGKDT-----AFICIVRNPISNSSSSPILTR--KFCEGG-G-GPDSL-
-------------MVILILLLGL---------ILLSLLLVGI-AIWCLQK-DK-----EK
ESTER------------------KEKKDTH--QEISNFCSHSGENTEYDTVSYIAKT---
-VP-----MED--LASTLY-S----TVQIPRK---------------MENP------NSP
---PTTPDTPRL----F---TYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MGALLWSLLL-LL----------H----EAKG-FSGD-DE

PF07686 // ENSGT00530000063114_Domain_0 (106, 276)

DP-EEVVAVLQESVN
LSLEIPSNEEIDNIIWF-SQ--KN----LATVMPGK------------------------
-------------------------EGQRVILMSVDPRYQGRVSIPE---S-SY-SLCIS
NLTWEDSGLYQAQVNLKT--SQ---LLITKSYSLHVYR--RL-SKPHIT-----VNS-NI
SEE-GTCNISLTCSTERAGRDVTYIWL--SSQD-S--------------------AN-TS
HEGSVLSTSWRPVDKAL-----SYTCRVSNPVSNISSRPISVG--SFCADPGYP-EKP--
--------------STFCFLVKS-------L-VLLLLLVILVVGVCISQ----AW-KDSE
RPRER-------KL---ERNR-----ITL-------RKKGKSSSTPV-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCF-TFIYI--------LWQLTG---ST-ASG----SV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-T----LVTIQPEG------------------------
-------------------------G----PMIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFTRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCRMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICTVRNPVSSNSSSPILAR--KLCEGA-ADDSDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESIEE------------------KKRADIC--RETPNIRPYSGENTEYDTIPYTNRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------IENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

MLRRMQSPLRQATDVWMQ---------------------------------------EAA
GMGRSSRLFPLPFLLLLF----------LLQP-W------A-GTGAS-RDLIGAVWGSVT
FPLDIQARRQVKCIKWT-SD--GD----IATVIPGG------------------------
-------------------------P

PF07686 // ENSGT00530000063114_Domain_1 (207, 257)

GKPPRIVVTAQQYMGRLTVS----T-NL-TLTIS
PLSLRDTGTYRADVNTAD--TT-----TTTQFSLR-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------AGPKRHP-----GGGAP----------RPFSSKPWK
SQPHAFSSFLWNSLLFLF----------L-----GPG-ASG-KDSAQ-MEVPGILEGSVT
FILNISIDKELEHVTWS-RP-QKA----LAFANA-Q------------------------
-----------------------------KDIIIMDKSYQDRLNISF---N-SY-SLSLN
NLTLEDAGPYKAQINYKN--AK---VTTDKEFFLHLYE--QV-QEPQ

PF13927 // ENSGT00530000063114_Domain_2 (288, 390)

VI-----IKSVNK
SDS-GSCNITLICFVEKARTSVLYSWT--GRDA-N--------------------AS-ES
HEGSTLTIQWTLCHPDL-----PYTCTAR

ENSGT00530000063114_Linker_2_3 (390, 427)

NPVSQNTSSPVRVQ--QFCTAPGASKGE-PM
GET---

PF07686 // ENSGT00530000063114_Domain_3 (427, 565)

-VVG--------VLGES-------VTLPLTFS-ASHHIENVIWM-LN-----TS
IISKE---------------QKEMATADPP--I----KFKDPNKN--------SSQDFSL
KI----DQVKME-N-AGHY--SAY

ENSGT00530000063114_Linker_3_4 (565, 590)

VCSEASRVIKTKH--ITLLVYGRLK

PF13927 // ENSGT00530000063114_Domain_4 (590, 675)

KP----KITWS
-LELAENDICRVSLTCSVEDSGHNVTYR--------WTPLPKGT---IESQRGPHLNVFW
TSGENHPNFTCIASNPVSSSSQQFLS-GNICPGPKRSM---KFYIVIFTV-MAVIVLCFV
TT-WCIWKRKRPCLSGSAP--TSCPSQAETPV-EEP--------------GYQELDTLPQ
PAKQQTRST----SDGSET-SE---EDQ----ERTDT--PKAGRHQKYALVNQEDTEFDS
ASEGQAEYDLVTPERMVPASVAQNSTVYTQVFLNSRGKTSVPQQKENSATIYSSIQTP-Q
RVVPPPQQND----PESPEIPTYENFT------

-------------M----------AGPERQS-----DYCTL----------RPFSGKPQK
SQPQIFSPIQWTPLLFLF----------M-----GPG-V

PF07686 // ENSGT00530000063114_Domain_0 (100, 277)

SG-ENSAP-TVVLGIVGASVT
LHLNISLDTEIEHVTWL-NS-KNA----LAFAKP-R------------------------
-----------------------------KDVIFMTKSYQDRLTISP---W-NL-SLHIS
NLTLEDEGLYTAQINRKN--SE---VTTKEKFILHIYE--NA------------------
-----SCDVTLTCSVEGAGESILYSRA--PRDA-H--------------------GS-ES
SGSSTLTISRMPFDPDL-----AYTCTASNPISQSSSRPVPAQ--QFCTDPGASKGG-IM
GET----IVG--------ILGES-------VTLPLAVP-ASEDKEKVVWM-FN-----AS
VISKE---------------KGEAATADLL--T----KSKELDTDRVWV----SGQDYSL
KI----SRLQME-D-AGPY--RAYVCSEASRVPSSKH--ITLLVYRKLKKP----NVTWS
-LKLTKNCICRVTLTCSVEDSDDNVEYI--------WTPLQKGA---VVSQGGSRLQVSW
RRGEKHPNFTCTAMNPISNSWHF-PG--SISXXXXXXX--XXXXXXX-----XXXXXXXX
XXXXXXXXXXXXXSALAFN-----SSQAEVPA-NIPEHSVDCTLYSMLFQEHEKLDTPPK
TDRQRPRPTSNSSSNSSIT-------AE----EKPEIPKSANRRDEAYDLVTQREPGHDS
ASEEQPEYELVTPYDRALESVVEGGTVCTQVFLNMQGKTPAPHKNDCSPTVYSCIQKF-Q
RVAPPPPQND----PESPKISVYENFT------

-----------------------------MV-----VSRTP----------APD------
SAGQM---MVWL---FPL------V-FCLGSG---NE-VPQ-SS

PF07686 // ENSGT00530000063114_Domain_0 (105, 276)

QSP-RVVNGVLGESAT
LLLELPAGKEASLIIWH-HKGEASQDTTILIVQLNK------------------------
--------------------------SKTPRIIESDPKRGERLSII----Q-SY-SLQVN
NLTMADAGLYRAQITTKD--P----TPDFSIYKLRVFE--RL-SNLEIT-----NHT-RL
FEN-GTCEIHLTCIAENPNQTVSVGWR--TSGS-I--------------------S----
LGEPNLTVSWDPKNSND----QSYTCQAENAVSNLS-VSVSAQ--SLCKGVLPEKNL---
----------Q-WHQTF-----I-------IIGTLLAI-VVVCLVI--WK-Q--------
--PCS--------------PTT----DNSS--QNTD-TPGSPGSNTVYAQVTHPV--QEM
EIP---KSIKN--DSMTIY-----SIVNHSRE----------------DQY------S--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCF-TFIYI--------LWQLTG---ST-ASG----SV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-T----LVTIQPEG------------------------
-------------------------G----PMIVTQNRNKERVHFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFTRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCHMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICTVRNPVSSNSSSPILAR--KLCEGA-ADDSDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESIEE------------------KKRADIC--RETPNICPYSGENTEYDTIPYTNRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------IENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MAGSPTCF-TLIYI--------LWQLTG---ST-ASG----SV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-T----LVTIQPEG------------------------
-------------------------G----PMIVTQNRNKERVDFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFIRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCRMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICTVRNPVSSNSSSPILAR--KLCEGA-ADNSDSS-
-------------MVLLYLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESIEE------------------KKRADIC--RETPNIRPYSGENTEYDTIPYANRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------IENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

---------------------------MVSP-----GRS---------------ADKPPE
GQVAFFSPYLWIAVLFLV----------------LGP-VSG-VNSNP-TLVKGMVGGSVT
LPLNISTFSEIEHVTWN-GP--QK----ALVLVPST------------------------
-----------------------------GNAIFMDKLNQDRLSVNN---Q-NY-SLSIY
KLTQKDVGTYKAQINRKT--S---EITAEEEFTLLIYE--RL-QKPQVT-----VKSVAI
SKD-ASCTVTLLCSVEG--TDVSYSWI--PRVS-N--------------------VS-ES
YGNSTVTLSWTPCDPDQ-----HYTCKARNLVSQVNSSSIFIQ--HVC

PF07686 // ENSGT00530000063114_Domain_3 (409, 585)

SDPDTSEGR-PV
A---------G-------LLGES-------VTLPLALP-AHQGIKGVIWV-FN-----TS
IINKV---------------PA--PVT------------------ASPL----VSQDFSL
KI----DSVTMK-D-AGTY--QAFLCSKASKVIHSER--ITLHVYRRLQKP----SITWN
SPGPLEGGVCRVSLTCSVED--SNVTYT--------WSPLQKGA---MVSQEGSRLTVCW
RSGDTHPTITCTASNPVSNSSQKFVP-GDICPAPKKER---NIVIGVSV---FFTLCFAG
IAVWYIWKKKRCGSAPTTNFSQEK-----SPD-VTQDSTMGL---TLLSRGYDMLGMTPR
TAGKQPPSDCSSSD-SNLT-TEEDEE-------RKVMHMAGPGRDQAHGQVTQGKPKQVQ
TTP----------GSMTPLFEVKGDTVYTQVFFNSQGKTPLSQENENSATIYSSVQGL-Q
E--------------------------------

------------------------------------------------------------
-----MYAFPWLLRLLLL----------Q----EAKG-DSGD-GVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-EEVVAVLQESIS
LPLEIPPDEEAENIIWS-SH--KT----LATVVPGK------------------------
-------------------------EGHPATIMVTNPQYEGRVSLLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRS--SQ---ISIMQQYNLRVYR--RL-SKPHIT-----VNF-EI
SGE-VACNVSLMCSVEKAGMDVTYSWL--SWED-S--------------------TY-TS
HEGPVLSTAWRPGDSAL-----SYTCRASNPISNVSSRPIPAG--PFCADPDYASEKPS-
--------------TDLCLLTKG-------L-LVFLLLVILAIGIWVIR----VQ-KRCR
MPRMK-------KL---RRNR-----MKL-------RRKAKPEKEGKAWL----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-------------M----------AGPKSHT-----DDWAL----------APFSNKPQK
SQPQILSAVLWTSLLFLL----------M-----GLR-ASG-KDAAP

PF00047 // ENSGT00530000063114_Domain_0 (108, 270)

-TVVSGILGGSIA
LSLNISEDTEIEHITWS-GP-KTT----LIIAYP-E------------------------
-----------------------------GKITLVDKSYQGRLN-TS---W-SY-SLYIS
NLTVKDAGTYKAQINQKN--SE---VTTEKEFTLHIYE--QL-QEPQVT-----MKSAKV
SEN--SCNITLRCSVEGAEKDVLYSWT--PRDT-H--------------------AS-ES
NDSSILTIFRMPCHPNP-----AYTCTARNPVSKNSSRPVRAG--QFCTGPGASRRG-AM
GET----VLG--------ILGEP-------VTLPLALS-ASQDIDNVVWM-FN-----TS
VISKG---------------QGEAATIDPL--I----KSRDPFKNRVWV----SGRDHSL
KI----DPLKME-D-AGLY--HAYVCSKASRVTSMTH--ITLLIYRRLARP----KVTWS
-LGQAKDGICRISLTCSVEDGGNNVTYT--------WAPLPKGA---LVSQGGSRLSIAW
RSGENHPNVTCTASNPVSSSSSQFLS-ENVCPGPESQV---KSWIVLSLV--VFLLCFGI
FS-WCLWRHKRQCSAPAFR-----SSPVEAPA-VTPEPTAGHTVYSMLSHGHEKLDSSDK
PARQQPRPTSDSSSDSNIT-TE---EDE----ERPETHKPVNGRD----------AGHDS
ASQGQAEYDLVAPNDTAAESVVEGGTVYMQVFFSSQGQTPLPQKRDSSATIYDSVQKS-Q
TVVPPPQENN----LESPEIPTYENLT------

------------------------------------------------------------
----MAGSPTCF-TFIYI--------LWQLTG---ST-ASG----SV-K

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

ELVGSIGGAVT
FPLKSEV-KQVDSIVWT-FNTT-T----LVTIQPEG------------------------
-------------------------G----PMIVTQNRNKERVHFPD---G-GY-SLKLS
KLKKNDSGIYNVEIYSSS--LQ---DPFTRKYVLRVYE--HL-SKPKVT-----MGL-QS
NKN-GTCVTNLTCHMEHGEEDVIYTWK--ALGQ-A--------------------VN-ES
HNGSILPISWRWGESDM-----TFICTVRNPVSSNSSSPILAR--KLCEGA-ADDSDSS-
-------------MVLLCLLLVP---------LLLSLFVLGL-FLWFLKR-ET-----QE
ESIEE------------------KKRADIC--RETPNICPYSGENTEYDTIPYTNRT---
-IP-----MED--AANTLY-S----TVEIPKK---------------IENP------HSL
---LTMPDTPRL----F---AYENVI----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-MAFS---LPWSLLLLGL----------L----PGPG-ASR----AP

PF07686 // ENSGT00530000063114_Domain_0 (108, 276)

-TVVTGTLGGSVT
LPLQLQDGQQVESISWV-CR--SV----PGAIATVT------------------------
----------------------LVEAGGPDTFHQADSRYWGRLSVVG---P-DR-SLKIS
HLSWADAGSYRAHVNLRS--S---RLTHTREYSLHVYE--KL-TQPHVT-----MST-RI
SGN-GHCLIILTCVAESRGGTVTYSWT--PLGP-Q--------------------TT-LS
HGGSILSVTLQPGDSAL-----NFTCTVKNPVSNSSSLPILVL--PSCSGPGILGSE-ES
VGE----TVIG-------TLGKS-------ATLPLEIP-VGQEVEKVTWS-SR-----GL
VAILQ---------------PG--PAGEPI--L--VAGNQGPYSQRLSI----PCHSYSL
QI----SSLRLQ-D-SGPY--RAWITLHSPPINITKD--FILHVYEKPQEP----KITAS
-SQIMKDGTCFITLACLLDQAGEDVQYS--------WDPRGQGA---VVSHGGTTLSISW
RSGVSD-SYHCTVKNPVSQSSSSISV-KPLCSGSFLPCCLRKEFIL--------FLILGA
LQIK--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLWLFQSLLF------V-FCFGPG---NV-VSQ-SSSTP

PF07686 // ENSGT00530000063114_Domain_0 (108, 267)

-LMVNGILGESVT
LPLEFPAGEKVDSITWL-CNGT-S----LAFIVPHE------------------------
--------------------------TKSPEIHMTNPKQGKRLKFT----Q-SY-SLQLS
NLKMEDTGSYSAQISTKT--S-----AKLSSYTLRILR--QL-RNIQVT-----NHS-QL
FQN-RTCELHLTCSVEDADDNVSFRWE--ALGN-T--------------------L----
SSQPNLTVSWDPRISSE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDVKI--Q----
----------Y-TDTKMILFTVS-------GICIVFGF-II--LLLLFLR-KR-------
--R-D-------SL-SLSTQRT-QGPE-SA--GNLEYVSVSPTNNTVYASVTHSN--RET
EIW---TPTEN--DTITIY-S----TINHSKE----------------SKP------TF-
---SRATALDNVV-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MVGFPACF-IRLSL--------LCQLTG---SA-

PF07686 // ENSGT00530000063114_Domain_0 (99, 277)

ASG----AL-KELFGALGGSVT
FPLELPE-QPVDSIVWT-FNSA------LAIIQPAG------------------------
-------------------------ANKSANVIVIQSRNKDRVSFLD---R-NY-SLSLS
QLRKNDSRAYHVEIHSL----F---QIFTQKYVLRVYX--XX-XXXXXX-----XXX-XX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--------------------XX-XX
XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXX--XXXAAD---GKDTS-
-------------VVFLYIQSSF----------FLLSLVLGLVIQ-IKRE-RR-----KE
KIIEE------------------KKGMDNH--QEIPKFYPLSGENTEDYTIPHPNKT---
-VL-----ED---PVNTIY-S----IVQTPKK---------------VEKP------HSP
---SRTSDTPGL----F---IYEQII----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------MLRLFQLLLL------V-FCFGRG---NL-VSQ-TSS

PF07686 // ENSGT00530000063114_Domain_0 (106, 268)

TP-LMVNGVLGESVT
LPLEFPAGEKIKSITWH-HNGT-S----IAFIAPSE------------------------
--------------------------AKSPQIHVTNPKWGKRLNFT----Q-SY-SLQLS
NLEMEDTGSYSAQMSSDT--S-----VNVSSYTLRIFR--KL-KNIQVT-----NHS-QL
SQN-RICEIHLTCSVEDPDDNISFKWE--ALGK-T--------------------L----
LSEPNLTTSWDPRNSSE----QDYTCIAENAVSNLS-FSVSAQ--KLCGDVEN--Q----
----------D-TDTNMILVVVV-------LGTCIVIF-II--VLLLFLK-KR-------
--RAG-------SL-PLSTQQT-QGPAESG--GNTDNASSSPVNNTVYASVTHST--TEM
ETS---TPIEN--NLLTIY-S----TINHSRE----------------SNP------TS-
---SRATALDNVM-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

-----------------------------VA-----ASGSP----------API------
STLQR---MIWL---FPL------V-FCLVSG---KM-ESQ-SNSTL-FV

PF07686 // ENSGT00530000063114_Domain_0 (111, 273)

VNGVLGESVI
LPLELSARKEVNLIIWH-YHPEASPAIAIIVININE------------------------
--------------------------FKIPQIITANPERKTRLNVT----Q-SY-SLQFN
NLTMADSGFYTAQITLKS--S----EMEVSSYVLRVLK--RL-SNLQVS-----NHI-QL
SEK-GTCEIHLVCTVENLKCAESFGWL--ASGN-I--------------------S----
LSESNLTVSWDPTNSSD----LNYTCIAENSVSNLS-VTVSAQ--SLCKDVFPKENL---
----------H-WDNIWTIII-------------VSIG-IIILVFIYAWK-K--------
--RTG-------SL-S-LATQH----LASS--QNTEYTLGSPG-STVYAQVTHPN--QRM
DNP---TYIKN--DSVTIY-S----IINHSRE----------------GNC------S--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
--------ALRGFFWLLF----------LCGQ-WWSG-EHG-GDAAP-EELNGF

PF07679 // ENSGT00530000063114_Domain_0 (115, 276)

LGGSVT
FPLDIPAGQQVESVSWT-SK--GA----VATAIPGE------------------------
-------------------------PGNPPSIIAPTQRYKGRLTVT----A-NY-TLTIS
NLNREDAGTYRADVNTAE--TT-----TVTQFSLHVWG--QS-RRDSTFSEFTL------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MVGFPACF-IRISL--------LCQLTG---TA-ASG----

PF07679 // ENSGT00530000063114_Domain_0 (106, 276)

AL-KKLVGDVGGSVI
FPLNIQE-QQVDSIVWT-FNTT------LVTIQPGG------------------------
-------------------------ANKLDNVIVTQRSNKDRVNFPSITPK-NY-SLILS
NLRKNDSGAYRVEIHSSQ--LE----MFTQRYELRVYE--HL-SKPKIT-----MGL-QN
KEN-GTCVTNLTCSMEQGGEDVTYSWK--SLGT-T--------------------AN-ES
HSGSTLPISWALGESNT-----IFICVVKNPISSNQSNPVSAE--KFCEVP---------
------------------------------------------------------------
-EIIE------------------EKGTDIY--QEITNFCPHSGENTEDDTVSDPYKK---
-K------LED--PVNTVY-S----TVQLHIQ---------------VQKP------PSL
---STTSDTPAL----F---PCENFVYSNAL-----------------------------
------------------------------SSHLTTEKKHKRD-----------------
-FTHFIRNIKEK------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
M---KEKNPKTQDEQC------------LRKFLRSEA-IER-EPDCS-M

PF07686 // ENSGT00530000063114_Domain_0 (110, 261)

VLNGILGESVT
LPVDIKDGQKINNIAWTS-K--SS----VAFVTPKV------------------------
-------------------------GGH--ELTVTQDIYKGRLEVTN---Q-TY-NLIIR
NLRMKDAGTYKADINEKN--R---EKTITKIYCLQIYS--RL-AKPKIT-----KSS-IT
SLN-NTCNITLTCSVEEEEKNVVYSWS--PSGE---------------------------
-ESNVLQIFHSPMDQKL-----TYTCTASNPVSNNS-DSVTVQ--QPCTDSP-SFHPYHG
V-----------------LP-GG----LA--ALSLLML-IPVVALLFHLY-KRRR---GR
IVLEA----------------D-DVSKKII--YSAVSRNAHLTESRIYDEIPQST-----
-M----LSRTEE-PVTTIY-S----SVQLYEK---------------TGKT---------
---NMKDERPPK------TLCNEIVV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MCAFTWLLLLLLL----------Q----EGDQ-R-----RLW-R

PF07686 // ENSGT00530000063114_Domain_0 (110, 276)

WLVAVLHESIS
LPLEISPKEEVENIIWS-SH--KS----LATVVPGK------------------------
-------------------------EGHPATIMVTNPHYQGRVSFLD---P-SY-SLHIS
NLSWEDSGLYQAQVNLRT--SQ---TSIMQQYNLRVYR--RL-SEPQIT-----VNF-EI
SGE-GACNMSLVCSVEKAGMDVTYSWL--SSGN-S--------------------AY-TC
YEGPVLSTSWRPGDSAL-----SYTCRASNPISNVSSRPILAG--SFCADPNYASEKPS-
--------------TAFCLLAKG-------L-FVLLLLVILATVLWVIR----VQ-KRRK
MPRMK-------KL---MRNR-----MKL-------RKKAKPASSPA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----------------------------------

PF07686 // ENSGT00530000063114_Domain_0 (96, 277)

SA-VSE----AM-MDLVGAVGGSVT
FPLKNTG-KQVDSIVWV-FNIT------TLVTR---------------------------
-------------------------QPERATVIVTQNRNTERINFTD---K-DF--LQLS
KLQKNDSGVYRVQVYSSS--SE---LPFTQEYMLRVYX--XX-XXXXXX-----XXX-XX
XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX-X--------------------X---X
XXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXTFSSPILAG--KLCEDD---GSVSS-
-------------MVFLQLLCLP----------ILVIFFISTLIHLRMRR-ER-----KE
ESTEG------------------KERMDIH--QEVPHFCPSSGETTEYNTISYSNXX---
-XX-----XX---XXXXXXXX----XXXXXXX---------------MESP------CSL
---PTIPGIPRP----T---TYENII----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
----MFGSPVCF-IYVSL--------FCQLTG---XX-

PF07686 // ENSGT00530000063114_Domain_0 (99, 277)

XXX----XX-XXXXGALGGSVT
FPLEHLV-KQGDSIVWI-FNTT------LATLQPQE------------------------
-------------------------PKKSAIVIVTQSHKKERVSFPN---R-DYYSLQLS
KLQKNDSGTYRVEIHDSS--QQ---SPYTQEYVLRVYE--YL-SKPKVT-----MGL-QN
KKN-GTCMTNLTCSMEQGGEDVTYSWK--I-------------------------AN-QS
HDGSILPISWRLGEKNL-----TFICMVKNPISSNSSNPISAW--SLCQGA-AGDTDTP-
-------------MLLLCLPVVT----------ILLVILALGLFVSSMQR-DK-----RK
XXXXX------------------XXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXTT---
-TP-----EQD--EICTLY-S----TVQILQM---------------VEKP------HLP
----ATPDPPE-------LLAHETI-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------

------------------------------------------------------------
-----MYAFPWLLLLLRL----------Q----E-------D-DVDP

PF07686 // ENSGT00530000063114_Domain_0 (108, 272)

-EEVVAVLQESIS
LPLEIPPDEEVENIIWS-SH--KT----LATVMPGK------------------------
-------------------------EGHPATIMVTNPQYRGRVSLLD---P-SY-SLHIS
NLSWEDSGLYQARVNLRS--SQ---ISIMQQYDLRVYR--RL-SKPHIT-----VNF-KI
SGE-GACNMSLMCSVEKAGMDVTYSWL--SWGD-S--------------------TY-TS
HEGPVLSTAWRPGDSAL-----FYTCRASNPISNVSSHPIPAG--PFCADSDYASEKPS-
--------------THFCLLTKG-------L-LIFLLLVILAIGIWVIQ----VR-KRYR
MPRMK-------KL---RRNR-----MKL-------RRKEKPGSSPS-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------