Query Results 

------------------------------------------------------------
---------------------------------------------MLCFLDDGCGMSPEE
AS-NIIYFGTSKKLLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSWLTRTRESVTDDPQKFSTELSIIYKYSPFKTEAELMKQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILIAGALEEGIFPERWSFRAYTSVLYF
DPRMRIFIQAQRVKTKHLCYSLYRPRKYLY---VTSSFKGVFKNEVKKAE-EAVKIVQRK
EKEIQQRKEQSRMTSAFDLLNSSRQSRRQVGNVLQKALEDVEAKHKVLKEKQ----RELK
KARTLSLFFGVNIEN-------RSQAGVFIYSNNRLIKMHEKVGPQLKLK--LGAGVVGI
VNIPLEIMEPSHNKQEFLNVLEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGCQNN--KDMEKSLDSIQCQRRQAMAIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIIQCDL
CLKWRILPPTTNYQEKEFFDIWICANNPNLLENSCHQTEHLPSIPLGTMSTVS-PSKTEK
EKRLRESIQRYQNQLAKQQ-PR--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

--------------------------------------------MGDKYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGATRLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSALKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSWLT

ENSGT00530000062983_1_Linker_0_1 (199, 595)

KTRESVTDNLQKFSTELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAL--EDFPERWSFRAYTSVLYF
DPWMRIFIQAKKVKTKYLCYCLYRPRKYLY---VTSSFKETFKNEVKKAE-EAHNILSL-
-------------------------PNVLFQDVLQKALEDVKAKHKILQEKR----RELK
KARTLSLFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVKEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYQNN--KDTERSLDSVQYQRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRILPPSTDYEEKECFDIWICANNPNLLENSCHQTEHLPSIPLGTMSTVS-PSKNEK
EKQLQESVQRYQNRLAEQH-RQPQFIPTSRITEFTTTSCSLLFKENTKTQRIRPSG-NDL
KHESLLSFELSDNPRG-GKR-STEGSDSDI--EYVSETKITKKSMQKKVKPQQ--WRHPA
ALLENV--KLAKRPQVCVC-----------------------------------------
-----------------------------------------------LCVCELCCDILEI
KRNSSSPNW-----ES-----MPVEDLNPS--SGNKARV--SVSGGCKVASSLTESSQRA
SVKETVRKLTSNLREILLYFFPEYQVPSELGHT-SLEELIGN--SELEQCPEKTNKKLKM
CFNQIQDVYMAQYEKKLKRKM-QSIIYDANRRGVVNEVSLVQCEEKRKTTEDKLNNLRIK
LAVLLKKLQLGGPAGDLEQIDSYLEVLLKEDNLF-QKTFK--------------------
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAVRLDVFSVDNETLQGGFMLCFLDDGCGMSPDE
AS-DVIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDCILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESITDDPQKFFTELSIIFKYSPFKTEAELMQQFDMIYGR
-----CGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEAP--EEIPERRSFRAYTAVLYF
EPRMKIFIQAKRVQTKHLCYSLYKPRKYQY---TTSSFKGKFKTEVQKAE-EAVKRAELL
FKEVQAKVNQPDRI-----------ALSSTQDALQKALQDVDTKHKSLRQKQ----RALR
KARTLSLFFGVNTED-------QHQAGMFIYSNNRLIKMYEKVGPQLKMKSLLGAGIIGI
VNIPLETMEPSHNKQEFLNVQEYNHLLKVMGQYLIQYCKDIGI-----------------
-------------SNRNLTLFWDEFKYQHS--KDTDSSLESLQWRRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

ILQCDL
CLKWRVLPSSSNYQEKGLPDLWICASNPNNLENSCNQIERLPSIPLGTVNRRP-PSKDER
ERQLQESVQRYQDKLVEAQPQKSQLIVTSKIPEFKSSCLSSALKEKSKLGRIQPSGADLT
QGSP-SSVKLSFMQRSQKR--STEDTHSDV--EFICMTKIPKKSVKKTVKYLQP-G-HAP
ALLENL--K---------------------------LEDTAQVSSREIKKQQSESLVQAG
KASTDV-ASSR-DPTVTMVWDQS--STKVSLKQEEEEEV----PLIKPDKQELCDDTPVV
KGNSSALHW-----KSL--PGVQMEDLSPR--SGHKI-N--SVSGDCQLPASPM-PSQSM
SVEETARKLLSNLREILLYFVPEFQLSSEFECT-SVEELITN--PELERCPENINEKLKT
CFNQIQNIYMAQYEKRLKRKM-QSIVYEANRRGLLNQVFLGQCELKRKRTEEKLSDLRAK
LALLLQKLQLGGPAGDPQQIDAYLEDLLKEDRLPT--ALH-EKSPESA------------
---------------------------------------------

--------------------------------------------MDDKYTALRRAQLNLD
FIHANSTTHSFLFGALAELLDNAXXXXXXXXXXXXXDNEELQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSSLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSWLTRTRESVTDDPQKFSTELSIIFKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAL--EDFPERRSFRAYTSVLYF
DPWMRIFIQAKRVKTKYLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAELI
LKEAQIKGNHSDRAS----------LSSPAKDVLWKALEDVKAKQKILQEKR----RELK
KARTLTLFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSSLDAGVVGI
VDIPLEFXXXXXXXXXXXXXXXXXXXXXXX------------------------------
XXXXXXXXXXXXXXNRNLTLFWNELGYLNN--KDMEKSSDSIQYQRRQAMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCDL
CLKWRVLPPSTNYQEKEIYDIWICANNANLLENSCHQTQRLPSIPLGTSSTVS-PSKNEK
DKQLQESVQRYQNRLEEPH-RQPQFIPTIRIPEFTTTGQTSAPKXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXX--XX--XXXXXXXX--XXXX-XX-XXXXXXX-XX-X---X----
XXXXXX--XXXXXXXXXXXXXXXXXKSQVANISTEGLLKNTSASSWEMKRKQRQNPVQEC
KALIEVETSNS-NLDIIQXXXXX--XXXXXXXXXX-XXX----XXXXXXTQELCSDTAEI
KRNPSSPNW-----ESLFLPSRPVEDLNSS--SGYEASV--SVRGGCKVASSLTTSSQST
SVKETVRKLTSNLREILLYFFPEYCLPSEFGHT-SLEELTAS--LELEQCPEQTNKKLKM
CFNQVRNVYMVQYEKKLKETM-QSIIYDANRRGVLNEVSLGQCEKKRKVTEDKLNNLRVK
LTVLLQKLQLGGPAGDLEQIDSYLEALLKEDNLLFQKTLN-KMTAGTGHSLLSKKESTSQ
N--------------------------------------------

----------------------------------------------DKYGGLRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 190)

FGALAELLDNARDAGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRSSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CETEGLSEV

ENSGT00530000062983_1_Linker_0_1 (190, 594)

VVPIPSWLTRTRESVTDDPQNFSIELSIIFKYSPFRNEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILVAGAL--EDFPERWSFRAYTSVLYF
EPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKEVFKNEVKKAE-EAVKIANLV
LKEAQITVNQPDRT-----------SLSSAKVALQKALEDVEAKYKTLKEKRRYNARELR
KARTLCLFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLFGAGVVGI
VNIPLEIMEPSHNKQEFLNVREYNHLLRVMGQYLVQYCKDTGM-----------------
-------------SNRNLTLFWNEFGYQHN--TDMEKSLDTIQYQRRKALAIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIIQCDL
CLKWRVLPSSIHYQEKEFFDLWICANNPNLLENSCCQAERLPSIPLGTMNTVS-PSKTEK
EKQLQEVVQRYHSRLAEQQPQKPQFVPTSRITEFTTTCQTSTSKEGN--TSILPTG-LEV
RKHTVSSIRKSASSESEDFL-AQEGLDSDV--EYVLDTK-MKRSTQKKVKPQQ--HRHPA
ALPENT--RLAQRSQ---------------------------LISWKMNRKQSQNIMQEC
KALIGVETSDS-DPDIILVLGKS--DADVSLKQKK-EVS----LMKR-EKQELCSDNPEI
KRNSSLPNR-----ESLFLHSALMEDSSPG--SGCNASF--SVSGGCNVASVLTKSSQGT
SIKETVRKLSSKLREFILNFFPEYQLPSGFGYT-SVEDLAASFEKQLEQCPEQINKKLRM
CFNQIQNVYMVQHERELKRKI-QSITYDANRRGVVNEISLRQCEEKRKVTENKLNSLREK
LAVLLQKFQLGSPAGDLEQIDGYLEALLKEDNPLFRNALNKKKTENS-------------
---------------------------------------------

--------------------------------------------MSHKYATLRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 195)

FGALAELLDNARDSGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEGEGLSEVVVPMP

ENSGT00530000062983_1_Linker_0_1 (195, 595)

SWLTRTRDSVTDDPQKFSTELSIIYKYSPFKNEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAD--EDFPERWSFRAYTSVLYF
DPWMRIFIQAKRVQTKHLCYCLYQPRKYLY---VTCSFKGTLKNEVKKAE-EAVKIAELS
LKEAQIKVNQPDIT-----------SSSSAKDILQKALEDVEAKRKNLKEKQ----RELK
KARTLFLFFGVNIEN-------RSRAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGL-----------------
-------------SNRNLTSFWNEFGYQRS--KDMETSLDSLQYQRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

MVQCDL
CLKWRVLPSSMNYQEKEFHDMWICANNPNLLENSCRQVERLPCIPLGTMSTVL-PSKNEK
EKQLRESVLRYQNKLAEQQSQ-----VTSRIAEFTPTCLTSTLKENTKTQKIRPSG-VDL
KHESLSPIELSVGQRS-QKR-NTEQTDCDV--EYVSDYKTMKRSVPKKMKPLLQ-RH---
TVPENI--QLAEP-----------------------------------------------
------------SQVIFQVLDKS--SPDVSLKQEQKEVP----LINE-EKQELCSDTPAI
KRNSSFPNQ-----ESS--SCVTMEDLNPI--SGHEAKV--SVSDGCKVASSLVTSSQST
IVKETARKLMSNLREVLLYFFPEYQLPSVFDCT-SAEELRAS--SELDQCPEQTNKKLKI
CFNQVSLSS----------RR-LSGVCPGNVSKL----------------------LAAF
PGVSIASLFQGGPAEDLEQIDVYLEALLKEDNL---------------------------
---------------------------------------------

--------------------------------------------MGDKYATLRRAQLHLD
FIHANSXXXXXXXXXXXXXXXXXXDAGASRLDVFSVDNENLQGGFILCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGCMRIGKDCILFTKKEETMTCVFFSQTF
CEREGLSEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXX
XXXXXXXTLLVIYNLKLLLNGEPELDVKTDKEDILIAGALEXXXXXXXXXXXXXXX--XX
XXXXXXXXXXXXXXXXXXXXXXXXXXKYLY---VTSSFKGTFKNEVKKAE-EAVKMAELI
LKEAQIKVNQPDRSS----------LSSPTKDVLQKAVEDVEAKHKILKEKR----RELK
KARTLSLFFGVNIEN-------QSQAGMFIYSNNRLIKMHEKVGPQLKLKSXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXX-XXXX------------------------------XXX
XXXXXXXXXXXXXXNRNLTLFWNEFGYQNN--KDMEKSLDSIQYQKRQAMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCDI
CLKWRVLPSSTNHQEKEYFDIWICANNPNLLENSCHHTERLPSIPLGTMSTVS-SSKNKK
DKQLRESVQRYQNRLTEQQP-QLQFIPTSRITEFTTTCQTSASKENTKSQKIRSSG-NDL
KHESLASSELSVSHRGQKR--NMEGTDSDV--EYISETKVMKKSTQRKVKQR---QKHPA
ALPENV--KLAKRSQKKQIAN------------IAQLLKNILASSWEVKRKQNQNLAQEC
KTLIEVETSNS-YPDLILVLDQS--DTDVSLKQEKKEVS----LMKK-EKQEPCSDAAEI
KRHSSLLNW-----ESL--VSVPMEDLNTS--FGHKARL--SVNGESKVPSLLTNSSQST
SVKETVRKLTSNLWEILLYFFPEYQLSSEFSYT-SVEELIAS--SELEQCPEQTNKKLKM
CFYQIQNVYMVQYEKKLKRKI-QSIIDDANRRGVINEISLVQCEKKRKITEDKLHNLHVK
LAALLQKLQLGGPAGDLEQIDSYLEALLKEDNLLFQNTLN-KGTTDTGQSLPLEKNESTS
QN-------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHAN----SFLF

PF13589 // ENSGT00530000062983_1_Domain_0 (74, 199)

GSTAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSILYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQVERLPSIPLGTMSTIS-PSKNEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLISANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRPPV
ALPENV--TLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASLPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSVIYDSNTRGIHNEISVGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNRLLQNNLN-KVTIDTRHRLPLEKK----
---------------------------------------------

------------------------------------------MAEAKGYLSLCRAELCLE
FLHANSTTHDFLFGAIAELIDNSRDAGATRLDILTVDNDNLQGGFMLCFLDDGCGMTPWE
AT-DLIYFGRSSKRFN-PTMIGRYGNGLKS--GSMRLGKDFILFTKKENTMTCLLFSQTF
CEMESLNEVIVPIPSWSSQTRNPMADDAEKFATQLSIIYKYSPFKNEAELMKQFDAIYGE
-----TGTLLVIYNLKLTITGETELDIQTDEEDVLITGAT--ENLPEQWSLRAYTAILYF
DPRMRIFIQAKKVETKRLPYCFYRPRMYPY---MSSTFKQVSVDELEKTK-MEVKAAEEA
VKEAKCTLKYSQDSL----------FQEDSELKLQHAQANEKRMREKLEDKL----RNLK
RPKKLYLIFGINIQN-------RSQDGMLIYSNNRLIRLFEKVGPQKDVESYFGAGAVGI
VDVPLDVMEPTHNKQAFANVKEYNHLLKAMGNCLVQYWKDMGI-----------------
-------------SQKGESLFWTDFGYLSD--NWCERPSNIIQYKRRRAVEIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

EIVQCDI
CLKWRLLSHDTDTNYEGHHDIWNCANSPNPLEKTCDVPEHLPSIPMGTFNPT--QSLDDK
QQLLVESIQERKRKMERLQSQKLHLIQPHTFV----HCPSSAKSSKDIVYRKKTSN----
KDSSP-ACRHLIKSRTK-----AEHSQHKT--HQRSSPAKQKTPSERRQQPCQKEKRFLS
VLEDTE---------------------------------DYSLPKVVPSEIQDEQFYHEV
PEVIKTETDS--DPEIISIIISDSEAEDLPKNEDGNDFS----FMQK-EEQEQSDEKEDY
LLSSASCSYFE---KTF--AKRDLESWSIGASHGNKEHVPDAVQESDAGTSNTQKDSKSI
PTMEMIGTLTSHIKEILLYFLPESINSKERIISMSSEDIMYMFK--L-KTPLEKNKT---
-VNLYIDEYLLQYEQQLLKKI-QGVKQHGLEALHATEREISLCEVQIKAEEDKLEALRRK
VAQLLFKIYPHHIINKLEDIDSFLEKILNSENLCAFDSENANTTETNTAVLPLPDENTEK
TSNSP----------------------------------------

---------------------------------------------MSKYASLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 200)

FGALAELLDNARDAGALRLDVFSVENETLQGGFMLCFLDDGCGMSPDE
VP-GIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPSWSTR

ENSGT00530000062983_1_Linker_0_1 (200, 595)

TRESVTEDPQKFFTELSIIYKYSPFKTEAKLMEQFDMIYGR
-----CGTLLIIYNMKLLLSGEPELDVKTDKEDILMAEAL--EELPERRSFRAYTAVLYF
DPRMRIFIQAKRVQTKHLCYSLYKPRKYQY---ATSSFKKKFKTEANEAE-EAAKMAELK
FKELQVKVHQPNRI-----------SLSSEKDGLQKAGDDAEAKHENLRQKQ----RALR
KARILPLFFGVHIED-------QNQAGMFIYSNNRLIKMHEKVGPQLKMKSLLGAGVIGI
VNVPLEIMEPSHNKQEFLNVQEYNRLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTVFWDELKYQHS--KDMDRSVESLLCRRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 640)

ILQCDL
CLKWRVLPSPSNYQE-EFPDMWICANNPNNMENSCNQPEHLPSIPLGTMSRRP-PSKDEK
EKQLQESVQRYQNRLAEAPPQKPQFIAMNRISEFKSSCLSTAPKEKSKLGRVGSAVVDLI
QGSPPSSVQCLSSQRGQKR--SLEDPDSDV--VFVSKTRILKRTVKEKVQPQQR-S-CVP
ALSGNV--K---------------------------VVEPSQVSSWEMKKRQSENLMQRC
KASTDVQTGSS-DPAVILVWSKT--NAKDSLKQEG-AEV----PLAKTEKQELCDDTLVM
KRKPSAPHW-----ESL--PGVQMEDLHPC--SGHKV-S--SVNGDRQLS-PLM-PSQSP
SIKETARKLMSKLREILLYFVPEFQLSSEFKCT-SVEELITN--PKLEQCPESTNEKLKT
CINKIQNIYMVRYEKKLKRKM-QSIIYESNRRGILNEVFLEQSELKRKRTEGKLNDLRAK
LALLLQKLQLGGPAGGLEQIDAYLEALLKEDHLT---SLN-ARALESGQ-----------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSILYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQVERLPSIPLGTMSTIS-PSKNEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRPPV
ALPENV--TLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASLPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISVGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNRLLQNNLN-KVTIDTRHRLPLEKN-EKI
PEN------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTFLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSILYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQVERLPSIPLGTMSTIS-PSENEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRPPV
ALPENV--KLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASPKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASLPA-SSQST
PVKETVRELKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISVGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNRLLQNNLN-KVTINTRHRLPLEKN-EKI
PEN------------------------------------------

--------------------------------------------MGDKYTLLRRAQLHLD
FIHANS

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 125)

TTHSFLFGALAELLDNARDAGAARLDVFSVGNEKLQGGFMLCFLDDGCGMSPEE
TS-E

ENSGT00530000062983_1_Linker_0_1 (125, 593)

IIYCGTSKKRSSAFRFIGQYGNGLK--SGAMRIGKDFILFTKKEETMTCL-FSQTF
CETEGLSEVVVPIPSWLTRTRQHVTSDPIKFSTELAVIYKYSPFKTEAELMQQFDMIYGK
-----CXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXFPEKWSFRAYTSILYF
DPWMRIFIQAKRVRTKHLYHCLYRPRKYLY---VTASFRGTFRNEVKKAE-EAVKFAKLM
LKEAQIKANTSDRTS----------SSSPAEDALRQALEDVEEKLKTLKEKQ----RELK
QAKTLPLFYGVSVEN-------RSQVGMFIYSNSRLIKMHEKVGPQMKVKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVREYTHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLSLFWNDLEYQNN--KDVEKSLDFVQYQRRQAMAM

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PLIIQCDL
CLKWRVLPSSANYQEKDFLDIWICANNPNPLENSCHQKEWLPSIPLGTMNTAL-PSKSEK
EKQLRALVHKYQNKPTEQQP-QLQFIPVDFR--AATVFQASAPKENTRTKRSRPSD-GDL
DRESLPSLDLSISHTGWKR--HTEGHDSDI--EFVSETKITRKTMQKKVKRPH--WRGPG
ALPENV--RGAKRSQXXXXXXXXX---XXXXXXXXXXXXXXXASSWEMKRKHSQNLMQEC
TALIEVETNNE-NPDRILALGKR--DTDISFKQEEKEVP----LVTK-ENPELCSVVPKI
QRNSSLPNS-----KXXXXXXXXXXXXXXX--XXXXXXX--XXX---XXXXXXXXXXXXX
XXXXXXXXXXXXXXKVLQYFFPEYQLSPEFDCI-FVEDPVTS--SELEQCPEHMNTKLKM
CFNQIQNVCMVQYEKKLKSKM-QSIISDAVRREEIDEVSLRQCEEKRKRTEDKLKNLRVK
LTSLLQKLHL--------------------------------------------------
---------------------------------------------

---------------------------------------------MVKYAALQRARLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 122)

FGALAELLDNARDAGATRLDVFSVDNEKLQGGFMLCFLDDGCGMSPGK
L

ENSGT00530000062983_1_Linker_0_1 (122, 595)

ICSIPNW--------LLKETNQYPLGSN---------CQRIFISKIRRCSTILFFSFFY
CEN----TVVVPIPSWITKTRESITDDPQKFSTELSIIYKYSPFKNEAELMQQFDMIYGK
-----CGTLLIIYNLKLLLSGEPELDVKTDKEDILMTGAL--EDFPERCSFRAYTSILYF
DPGMRIYIQAKRVQTKILYHCLYKPRHFVC--------------EISTLS-QIVKDRQLI
LKEAQIKTSQPNTI-------------SLPSNVLQKALEDVEAKRKNLKEKQ----RELR
KSRTLSLFFGVNIEN-------QSQAGVFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMELSHNKQEFLNVQEYDHLLRVMGQYLIQYCKDTGM-----------------
-------------SNRNLTMFWNDLGYQHN--KDLEKSS-EIQYQRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 638)

MMQCDL
CLKWRVLPYPTDFQKKEFLDAWICANNPNHSENSCDQVEWLPSIPLGTMNTAT-SSKSER
EKQLRESIQRYQNKLAEMKPQVR----------TTSTLLSSAPK------KLRIAS-DNL
KPGYLSSLEFSVNHRDQKR--NPEGADLYI--EHVSKTKIVKKSVSK---PQQ--QREAE
ALPENV--KLAQRSQVLSPCCKVFAQPSN-------------------------------
----TTHT-VLNKELVFQILDED--DTDVALKQEKQEIP----LLSRGK-----------
--NIQFLTWFLFSNCNFSLPRVPREDISPS--SGHEAKV--SVSVGGHVSSSLMTLSQST
SVKEIVRKLTSNLREILQYFVPDCQLPPGFEYT-SVEELLEN--SELEQCPEQKNKKLKE
CFNQIQNVYMVHYEKKLKRKI-QSLIYDVNRRAILTEISWGQCEEKRKKAECKLNDLRMK
VVVLLQKLQLGCPVGDLEQIDAYLESLLQED-----------------------------
---------------------------------------------

------------------------------------------------------------
------

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 118)

TTHSFLFGALAELLDNARDAGAARLDVFSVNNEKLQGGFMLCFLDDGCGMS

ENSGT00530000062983_1_Linker_0_1 (118, 600)

PXX
XXXXXXXXXXXXX---XXXXXXXXXXXXXXXXGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVLVPIPSWLTRTRESVLDDPQKFSMELSIIYKYSPFKTEAELMQQYDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAL--EDFPERWSFKAYTSVLF-
DPQM-ISIQAKRVKTKHLCYLY--RRKYLY---VTTSFKGTFKNEVKKAE-EAVKIAEFK
LKEVQFQVNNRNRT-----------LSSPAKEALQKALEDVEAKHKNLKEKQ----RELK
KAKTLSLFFGANIEN-------RSQAGMFIYSNSRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGIXXXXXXXXXXXXX----
--------------------------XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX

PF07496 // ENSGT00530000062983_1_Domain_1 (600, 642)

L
CLKWRVLPSSTNYQEKECLDIWICANNPNPSENSCQKTERLPSIPLGTMSTMS-PSKNEK
EKQLRESVQRYQNRLEEQQP-QLQFIPTSRITEFTTTGQTSAPMENTKTHKIRSSD-DYL
KHESLPSFELSVSPKGQKR--NTEGSDSDI--EYISETKIRKKTMQKKVKPQL--QRCPR
APAESA--KVAERFQREIVNITSVR----TQP--MAELLKNVASSWEMKRKQSQNLVQEC
TALSEVGTNNN-DPDIILXXXXX--XXXXXXXXXX-XXX----XXXXXXKQELCDVAPEI
KKNSSLSNW-----ESLFFPSVLMEGLRPT--SGHTTSF--SVNEDCKVASSLKKSSQST
SVRGTVTKLMSNLREILLYFFPEYQLPSEFDYT-SLEELVAS--SELEQCPEQINKKLKM
CFNQXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGGPARELEQIDSYLEVLVKEDNLLFQNT----------------------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLRGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
DPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAESI
LNEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDVEKPLNSIQYQRRQAMGIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIVQCDL
CLKWRVLPSSTNYQGKEFFDIWICANNPNRLENSCHQIERLPSIPLGTMSTIS-PSKNEK
EKQLRESVVKYQHRRAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESVSSFELSVSHRGQKR--NTEETDSDV--EYISETKIMKKSMGEKMNSQQ--QRIPV
ALPENV--KLAERSQKSQ--IANITSVWRAQPT-EGCLKNAQAASWDMKRKQSLNFVEEC
KVLIEDENNKS-DSDIILVSDKN--NTDVSLKQEKKEIP----LLNQ-EKQELCNDVLAV
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGHKARV--SVSGGCKVASSPT-SSQST
PVKETVRKLKSKLRRTLLYFFPEYQLPSELEEP-A-------LSCELEQCPEQINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDSYLEALLKEDNLLFQNNLN-KVTIDTRHRLPLEKK-EKT
PEN------------------------------------------

------------------------------------------------------------
------TTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAMRLDVFSVANETLQGGFMLCFLDDGCGMSPDE
AP-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGAMRIGRDFILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPSWTT

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRKSITDDPQKFFTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLVIYNLKLLLSGEPELDVTTDKEDILMADTL--EELPERRSFRAYTAVLYF
DPRMRIFIQAKRVQTKHLCYSLYKPRKYQY---ATSSFKGKFKTEVKEAE-EAVKMAELR
FKELQVKVNQPNTN-----------SLSSAKGELQKAQEDEETKHKHLREKQ----SALR
KAKTLSLFFGVHVED-------QNQAGMFIYSNNRLIKMHEKVGPQLKMKSLLGAGVIGI
VNIPLEIMEPSHNKQEFLNVQAYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLAVFWDEFRYQHS--KDLDRSSESLQWRRRKAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

ILQCDL
CLKWRVLPFLSNYEE-EFPDMWICANNPNNLGNSCNQPEYLPPIPLGTMSRRA-PSKDEK
EKQLQESVQRYQNRLVVAQPQKPQLITMSRIPEFKSSSLSSAAKEKSKLGRRGPSVIDRI
QGTPPSSGELLSCQRGQKR--STEDTDSDV--EFICMTKAPKRTMKEKVKHQQP-S-YAP
ALSQDL--K---------------------------SGEASQVPSWETKSRQSENLAQEC
KAFAEVETSSG-DPAVILVWDKT--STKVSLKQER-AEV----PLPKTEKQELCDETLVM
KGISSARNW-----ESL--PRMQMEDFSPH--SGHKV-S--SENGDHQLSSSPM-PSQST
PAKETARKLMSNLKEILLYFIPEFHLSSESECT-SLEELITS--PELEQCPESTNKKLKT
CLNKIQTIYMPQYEKRLKRKM-QSLIYETNRRGLLNEVFLGQCELKREKAEERLNDLRAK
LVLLLQKLHLGGPAGDLQQVDAYLEALLKEDHLPA--TLN-GRTLESGQ-----------
---------------------------------------------

--------------------------------------------MGDKYATLQRAQLLLE
FIHANS

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 125)

TTHSFLFGALAELLDNARDAGAARLDVFXXDNEKLQGGFMLCFLDDGCGMSPDE
AS-D

ENSGT00530000062983_1_Linker_0_1 (125, 593)

IIFFGTSKKRSSALKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCMFFSQTF
CEREGLSEVVVPIPSWLMKTREPATDDLQKFSMELSIIYKYSPFT-IAELMKQFDVIYGK
-----CXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXFPERWSFRAYTSVLYF
DPRMRIFIQAKRVKTKHLCYSLYRPRKYQY---VTSSFKAVCKNEVKKLE-EAVKIAELK
LRETQIQVNQSDKS-----------SLSSPEDALQKALEDVEAKHKILREKR----RELK
RARTLSLFYGVNIEN-------RNQAGMFIYSNNRLIKMHEKVGPQLKLKSXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------------------XX
XXXXXXXXXXXXXXNRNLTLFWNEFGSQSN--QDVEKTTDYIQYQRRQAMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCNL
CLKWRILPSSADYPEKDLLEFWICANNPNPQENSRHQAERLPSIPVGSISTVL-TSKNGK
EKQLQESVQKYHNRLAEQHP-QLQFIPAR-AKDFTATCQTSVTKETIKGKKIRPPS-KDL
KRESLASCELLINHRGQRR--NTEEMDSDI--EYVSETNVTK-SMKKKVKLQQ--QRHSA
TLPENI--KLAGSPQRSQT---ANTSIWRFQPTK--VSLNTWACSWEMKRKESQACIQGR
KTLTEVETSNG-YPDIILVLNES--NTDISLKQEKREDS----LMKK-ETQELCSDMPEI
KRNPSFSSW-----QSLLLSSDLMENLEI---PRHKSRV--SQIGDCKAASSLTESSQCI
PVXXXXXXXXXXXXDILLYFFPEYQLPSEFSCT-SVEELMAS--PKLEQCPEQTNKKLKI
CFNQIQNVWMAQYEKNLKRKM-QSIIFDANRRGVVNEISLGQCEGRRKVTEDKLSALRGK
LAVLLQKLHLGGPAGDLEEIDSYLEALLQEDNLLFQNTLR-KMTTD--------------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPDE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
NPRMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGALKNEVKKAE-EAVKIAEFI
LKEAQIKVNQCDTT-----------SLSSAKDVLQRALEDVEAKQKNLREKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTDYQEKEIFDIWICANNPNRLENSCHQIERLPSIPLGTMNTIS-PSKNEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NTEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRLPV
ALPENV--KLAERSQESQ--IANITSVWRAQPT-EEPLKNAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASSPS-SSQST
PVEETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKKKL-QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIK
LVLLLQKLQAGGPEGDLEQIDTHLEALLKEDNPLLQNNLN-KVTIDTRHRLPLEKN-EKT
PEN------------------------------------------

--------------------------------------------MANKYASLHRASLHLN
FIHANSTTHGFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 194)

FGALAELLDNARDAGATRIDVFSVDNEKLQGGFLLCFLDDGCGLSPEE
AS-HIINFGTHKKHLPTSKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVLFSQTF
CEEESLSEVVVPM

ENSGT00530000062983_1_Linker_0_1 (194, 597)

PSWLTRTKESIRDDPQKFSTELSIIYKHSPFQNEAELMQQFGVIYGT
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAL--EGFTETWSFRAYTSVLYF
DPSMKIFIQAKKVQTKHLCYCLYRPRKYLH---AASSFKGTLKNEVKKAQ-EAVKTAELI
LKEAQIKVNQPGRT-----------ASSSAQDILERALEDVEAKHKTLKEKQ----RELK
KAKTLSLIFGVNIEN-------PSQDGMFLYSNSRLIKMHEKVGPQLKWKSLLGTGVVGI
ANIPLEIMEPSHNKQEFLNTQEYNHLLRVMGQYVVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYQNN--KDVEKSLDSIPYQRRQAMDIPLIR

PF07496 // ENSGT00530000062983_1_Domain_1 (597, 636)

QCDL
CLKWRVLPSSTNYQKKEFLDTWICADNPNRLDNSCHGIERLPNIPLGTLNTVS-LSRSEK
EKQLRESIQRYQNKLLEQQA-QVSSLQITQLPNN--KTYFSFFKEYSKTQKIGPPSDDNL
RHESLSSSELSLDQRSQKR--NTDGADSDI--EFVSETKVTKKSTQKKLKSCE--QRPAA
TLPRNI--KPAEIAQVSFLSFFLFMK----------------------------------
------YLLSLFCLCSF-----------------------------K-EKQKLCSVTAAT
KRNSSSPNL-----RSL--PSEPMEEFSIS--SGHEARD--SASGCSKNAPLPTTSSQNT
SVKETVRKLVSILREILLYFAPKDLPSSEFNCT-TVEELIAN--IEQTQSPEQTNQKLKL
CFNQIQSVYMVQYEKNMKKKI-QSIIYDGSRRAILNEVSLLHCEQKRKLTEDKLNNLHAK
MAALLQKLV-RLPRRDPEQMDAYLEGLLEATHSFSKILSSDHRGG---------------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSILYF
NPCMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQVERLPSIPLGTMSTIS-PSKNEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRPPV
ALPENV--TLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASLPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISVGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNRLLQNNLN-KVTIDTRHRLPLEKN-EKI
PEN------------------------------------------

--------------------------------------------MGDKYILLQRAQLHLD
FIHANS

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 119)

TTHSFLFGALAELLDNARDAGATRLDVFSVDNEKLQGGFMLCFLDDGCGMSPEA
T--DIIYFGTSK-RLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFLSQTF
CEKEGLNEVVVPIPSWLTRSRHSITDDPQKLSVELSIIYKYSPFKTEAELMKQFDIIYGK
-----CXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXFPERWSFRAYTSILYF
DPWMRIFIQAKRVKTKHLCYSLYRPRKYQY---VTSSFKGAFKNEVKKAE-EAVKLAELM
LEETRIKVSHPGRTS-----------LSSPTKXXXXXXXXXXXXXXXXXXXXX---XXXX
XXXXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNYLLKVMGQYLVQYCKDTGIXXXXXXXXXXXXXXXXX
XXXX----------------------X--X--XXXXXX--XX----XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDGAQRLPSIPLGTMGSVS-TSKHEK
EKQLQDSVQRYHHRLAEWQP-QPQFIPPSRITEFPATCQKSAPKENMKTMKIRSLG-KDL
KRESLVSNKLSISHRGWKR--NAEGAHSNT--EFVSETNRIKTSMWKKVKFQQP--RRPV
TRTENV--RLAEKPQKNIPSI---STVYRVQ-LTERLPDNTCASSWEMKRKRNQNLVQDC
TTLIEVEDSIR-DPDVILXXXXX--XXXXXXXXXXXXXX----XXXXKAKQELCNDTPEL
KRNFPLLNW-----ESL--VSVPLEDFNPC--SGCNAKI--SVSGACSISSSPTEAPKST
YIKETVKNLLSNLXXXXXXXXXXXXXXX--------XXXXXXXXXXLERCPENTNKMLKM
FFKQXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXGHPEDLEEIDNYVETLLLEDDPLLRNSKN-KVTA--GHSQEKSKNSSQ-
---------------------------------------------

------------------------------------------------------------
---------------------------------------------MLCFLDDGYGMNPEE
AS-DVIFFGMSKKRKAASRFIGHYGNGLK--SGSMRIGKDFILFTKKEETMTCIFLSQTF
CESEGLNEVVVPIPSWSSKTKKSITD-LKKFSEELSVIYKYSPFKTETELMQQFDKIYTK
-----SGTLVVIYNLKLMLNGEPELDIKTDKEDILIAGVL--EDLPERWSFRAYTSVLYF
DPRMRIFIQTKRVQTKYLSYCLYRPRKYLY---VTSAFKGASKNEVKKAE-VAVKIAEQM
VKEARYKTNHSLQT-----------GLSSAKDMLKKALEDAEIKQKTLKEKE----KELK
KPKKFYLIFGVNIEN-------RSQDGMFIYSNSRLIRMNEKVGPQLRTGSLLGAGVVGI
VNVPLEIMEPSHNKQGFLNVKEYNHLLKIMGLYLVQYWKDTGF-----------------
-------------SNRNPMLFWNKFGYQSN--KWLEKPLNSARYRRRQASEIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 641)

FIVQCDL
CLKWRILPSSDDYKKRENLGNWTCANNPNILENSCHRPEQLPSFPLGTMKKAS-PSEDEK
DKQLRDSVQRYQNKLAEQQSQNSHLVPANKTTEFLPSSQASAPKEYAKSRTFVPQR-DAS
ERDAGSSSVVWARHLSHKRR--RSKSVSTP--SYVSEDKIPQTTVRKKVKVKQL-RRHLE
N----T-----------------------------KINENSQVSSWKVKKKSPEGVGKDS
KSIIEDED-NS-GPDLIIFTDEN--DAVMTLKHEKEETLKNKGLVSVDDKPKLRANTPET
KRNSSPLNL-----ESL-----SADDLSPR--PGQKERF---VKHECDVAVPFLKPSQST
CAKKTIEKLMAQLREILLYFHPHSKVSKDLDYK-SLEELMAF--FELENCPEKLNKKLQM
CCDQIWSVYMVQYEKKIRRKM-QSLTQQANKTAVNNEAHHKQCEKQIQIIENKLKSLRVK
VATLLSNWNMSTPSDDLEHIDSYIEALLNEENIFLPDTLK-LAATKSGQALPSYEE----
---------------------------------------------

--------------------------------------------MDDRYPALQRAQLRLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKDEVKKAE-EAVKIAESI
LKEAQIKVNQCDRT-----------SLSPAKDVLQRALEDVEAKQKNLKEKQ----RELK
TARTLSLFYGVNVEN-------QSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGIISKISERDYQENEYNNF
AKDTRRVRRQILKDNRNLTLFCNEFGYQND--IDVEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHHIERLPSIPLGTMSTIS-PSKNEK
EKQLRESVIKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSAHKENTKTQKIRLLG-DDL
KHESLSSFELSASHRGQKR--NIEETDSDV--EYISETKIMKTSMEEKMNSQQ--QRIPV
ALPENV--KLAERSQRSQ--IANITTVWRAQPT-EGCLKNAQAASWEMKRKQSLNFVEEC
KVLTEDE-NTS-DSDIILVSDKS--NTDVSLKQEKKEIP----LLNQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGHIARV--SVSGSCKVASSPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEQMNKKLKM
CFNQIQNTYMVQYEKK--------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MTCVFFSQTF
CEREGLSEVVVPMPSWLTSSRKSIADDPQKFSVELSIIYKYSPFKTEAELMRQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMTGAL--EDFPERWSFRAYASVLYF
DPWMRIFIQAKRVQTKHLCYCLYRPRKYLY---VTSSFKGVFKNEVKKAE-EAVKIAELV
LKEAQIKVNQLDRT-----------SLSSAKDELQKALEDVEAKQMNLTKKR----RELK
KKRTLSLFFGVNIEN-------RNQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGV
VNIPLEIMEPSHNKQEFLNVQEYNNLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLNFFWNEFEYQNS--TDIERPLASIQYRRRQAMAIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIIQCDL
CRKWRVLPPSTNYQDKEFLDMWICANNPNLSENSCHHVEHLPSIPLGTMSTML-PSKSEK
AKKLRESVQRYQNKLAETQP-QPQFIPTSRISEFISTCPTSAPKENVRSQKIRPSG-DDL
KHEPLSSFELSDSYRSQKR--LPEETDSDV--EYVSETKIGKKSMQKRMRRAA-------
ALSGGV-----------------------------RLPETFQASSWGMKRKQRLNFVKKC
KVLTEVETSNN-NPDVILVLNES--DTDVSLKQEKKEFP----LINK-EKQELYNDAPEI
KGNSSLSNQ-----QSL--LSVPVEDFSPS--SGHKA------SDGWKTISLLTVSSQST
SIKETVRKLMSNLREILLYFFPEYQLPSELDYI-SGEELAAS--SELEQCPEQTNRILQM
CLDQIQNVYMVQYEKKIKRKL-QSIIYEANRRGVLNEIALGQCEEKRKTTEDKLENLRVR
LAALLQKLQLGCPSGDLEQIDTYVEALLKEDNLLSCSTFN-KVTVGGLEVAQLELDPVVM
APKREGLKCSHNKKYFGNHIPLEIRILKTALRTVTPKHLQWPMLL

------------------------------------------------------------
------

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 125)

TTHSFLFGALAELVDNARDAGATRLDVFSVDNETLQGGFMLCFLDDGCGMSPEE
AS-D

ENSGT00530000062983_1_Linker_0_1 (125, 593)

IIYFGTSKKRLSAFKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPVPSWLTRTREHVTSDPIKFSTELSIICKYSPFKTEAELMQQFDIIYGK
-----CGTLLVVYNLKLLLNGEPELDVKTDQEDILSAGTLEXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXX--XXXXXXXXXXXXX---XXXXXXXXXXXXXXXXX-XXXXXXEPI
LKEAQTNVKKLDRT-----------SSSPAKNSLPEALEDVKAKHETPKGKQXXXXXXXX
XXXXXXXXXXXXXXX-----------XXXXXXXXXXX-XXXX--X--XXXXXXXXXXXXX
XXXXXXXXXX-X-----XXXXXXXXXXXXXXXXX-------------------XXXXXXX
XXXXXXXXXXXXXXXXNVSLFWHAFEKHNS--SNVEKSSDPDQHERRHIMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCNF
CLKWRALPSSTNYREKEILDIWICANNPNPLENSCHQMEQLPSIPLGTMSTAS-PSKTEK
EKRLRKLVLRYQNKLTELQL-QPQLIPPRRIADF--TCRTAPPKENTKTQRTEPSV-GDL
EQESLPSFDLSAIPKGHKR--HTDELDSDV--EFISETKMSTT-TQKTAKAHQ--WRHLT
VPPENV--RPSKRSQE---NIADISTVWKAQPIEVPCLKDVWVSSSKMRQGQN---FIEC
KSLIEVETNNE-NSYIILVLDKR--DTGISLKQEKKEVL----LMNKXXXXXXXXXXXXX
XXXXXXXXX-----XXX-----XXXXXXXX--XXXXXXX--XXXXXXXXXXXXXXXXXXN
TFVKEVRKLMSNSREILLF-FREYQLPLELDSE-YVEGSVAI--SELEQCPEQTNKKLKM
CFNQXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXGDPVGDMEQIDSYLEDLLKEDNFQ--NVLN-VVMIHSEHNLLVEEKKSNK
---------------------------------------------

GALVQFKVVLLVREFPASAKVLGIVIASQTLVNSTQRWAVRVQVMAERYKCLSRANLNLA
YIHANSTTHEFLFGAFAEIIDNSRDANASTLYIYSEPTRDFQGGQLLCFLDDGCGMTHRE
AC-DLIYFGRSSKRFTSSRFIGRYGNGLK--SGSMRIGKDFILFTMREDCMTCLLFSQTF
CETEGLDELIVPILCWSQSTKKPLTESSDIADIQMSILNRYSPFKTEQDLLKQFEYIYTG
-----HGTLIIVYNLKLMSNSEPELDFFTDISDIINAGMRDSDVYSELWSLKAYISVLYV
DPRMKVFVQATRVHNKQLIYSLYRPRCFTYSNPT---LPQQILCILLNSSPIFIVPANLA
VADIEQKM--AEHVS--------EKELEVLHCLLINNKKKLDEKCQILKEKK-----REK
QLKHVYIKYGLNIET-------RSQDGMFIYHNNRLIRMHEKVGRQLNKELSTGAGVLGL
VNIPSGALIPSHNKQNFINSQEYHKLLKHMGYFLDQFLKDSGI-----------------
-------------GEKGTVHFWNEFGYLSGLKDWFEVPSDAVHFIRRRAIEI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PKIIQCDL
CLNWRVLPSSASTF--DQPDNWTCADHPDPTKNRCTEPEQLPAIPVGTLPRKP-LQFTDK
EKRLRDSVERYKNKRLGSQKCNLT-EPHLAVPALL-------------------------
----------SIS--SKKRK--DESSRTDILSKRMADSQKYKESSQNRVVTRKH-NRDRY
RLNDSS------------------------------------------------------
---------------IITKGPHP--SSRLNLPVSKTELRICTTKVGKTLEKPLCSARSQT
EN------------AKNFILGAPAPSASSV--SENNV-------SKCIAEAGRTLEVPSC
SRKETEEKLKLTLGEVISYFVPDCQLPILETIY-K---------G------------DQA
QLGSLVNDYFKEYEENVLAVYLHAANDHFEAKAELNELMGEACEEQIKVVEQKISALSKK
AARIFKKLHINVPEESVLDTE----------RLLLQDQSEI-------------------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCLFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSILYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKTAEFI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDIEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 633)

IIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENRTFVTCH-PAV--TISTIIH-PSKNEK
EKQLRESSLKYTNRLAEQQ-PQPQFIPVDEIT-ITSTCLTSADKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRPPV
ALPENV--KLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASPKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASLPE-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISVGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNRLLQNNLN-KVTINTRHRLPLEKK----
---------------------------------------------

--------------------------------------------MGDKYSSLRRAKLHLD
FIHANSTTHSFLFGALAELLDNARDAGAARLDVFSVDNETLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGASKKRLSTLKFIGQYGNGLK--SGAMRIGKDFILFTKKEETMTCVLFSQTF
CEREGLNEVVVPMPSWLTGTKESVTDDPQKFSTELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNMKLLLSGEPELDVTTDKEDILITGAL--EGFPERWSFRAYTSVLYF
DPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGVFRNEVKKAE-EAVKIAELV
LKEAQIEENRSDET-----------SLPFAKDVLQRALDDVEAKHKHLKEKQ----RELK
KARTLSVFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGV
INVPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTSFWNEVGYQNN--KDMGTTLDSIQYQRRQAMAIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FMIQCDL
CLKWRVLPSSTNYQEKEFLDIWICANNSNLLENSCHHIEKLPSIPLGTMNTVS-PSKNEK
EKQLKESVQRYQNRLAEEQPQKPQFIPMDKITKFTSTSLTSAPKGNAKTQNIRLLD-DDW
QHETLASSEVSISHRS-EKR-TTEETDSDV--EYFSEMKIGKKSVQKKIKLQQQ-QIHPA
ALPENV--KLTDRSQKEKLDCQHQHRVWRLHPVQEACLENLEAPSWEMERKQVLNPAQKC
KTLIEVETSNG-DPDIILISDKS--DTDVSLKQEKKEIP----LTKK-EKQDLCNDAPAV
TRDSSLPPN-----QKR--LSVPEEDVNLS--SGHNDKV--PVSGRCEVASPPT-SFQST
AAKETVKKLMGNLREILLYFFPEYQLPSEFDYM-STEKC--R--KQPEQCLEKTNKKLKM
CFNQIQNIYMVQYEKKLKKKM-QSIIYEANNTGVLNEISLGQCEEKRRITEDKLKNLRVK
LAGLLQKLQLGGPEGDLEQIDSYLETLLKEDNFLLQNDFN-KVTVDTEHCLPLERKSTKK
NEN------------------------------------------

------------------------------------------VK--DDVPYLRKDQILIN
FYLSFSTTH

PF02518 // ENSGT00530000062983_1_Domain_0 (70, 152)

DFLFGAIAELIDNSRDAGATRLDIFTVDNNKLPGGFMLCFLDDGCGMAHKE
AT-DLIYFGRSSKRTSTSRMIGRYGNGLKS-

ENSGT00530000062983_1_Linker_0_1 (152, 595)

MGGFRRRKESHGATGSPETMTSVLFSQTF
CETEGIDEMIVPITSWSKSTRKPVISDLEKFTVQMSIIFKYSPFNSETELLQQFDAIYGR
-----SGTFIIIYNVKLTLSGEPELDIRTDHADIMITGLL--DNLPERWSLRAYTTILYF
EPHMRIFIQAEKVETKRLPYCFYRPRMYPY---IMSSFKGIARKEIKKAE-VDMKMAEQA
VEEAKCRLKHLEESL----------LHEVNELALQDALENAKRMREKLEEKQ----RELR
RPKKLYLIFGINIEN-------RSQEGMFIYNNSRLIRMYEKVGPHLKQGSQMSGGTVGM
VDVPLETMEPTHNKQAFVNVKEYNHLLTSMRHHLIQYWKDIGI-----------------
-------------SQKGVTSFWNEFGYISD--KWLDKPSDAIQYKRRRAEEIPV

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 640)

VAQCDV
CLKWRVLSSSTDIKNGYQHGIWTCAKIPGPLENKCNRPEHLPSIPLGTLNRLS-LSLNDK
EKVLIDSIQRHQRKLENLQFQVEYVP----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

--------------------------------------------MGDKYAALRRARLHLD
FIHANSTTHSFLFGALAELLDNARDAGAARLDVFSVDNERLQGGFMLCFLDDGCGMSPEE
KLSFTIEYGVSYQQLLSLVCIGQYGNGLKK-SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEKEGLSEVVVPIPSWLTRTRESVMDDPQKFSMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDIKTDREDILTTGAL--EDFPERWSFRAYTSVLYF
DPWMRIFIQARKVKTRHLCYCLYKPRKYLY---VTSSFKGTFKNEVKKAE-EAVRIAEFR
LKEAQSEVNNPDRTS------------FPAKDALPKALEDLEAKRRNLKEKR----RELK
KAKTLSLFFGVNIKN-------RNQAGMFIYSNSRLIKMHEKVGPQLKLKSLLGAGVVGI
VNVPLEIMEPSHNKQEFLNVREYNHLLRVMGQYLVQYCKDTGI-----------------
-------------SNRNLTSFWNEFGYQNN--KGMEKSSDSVQHQRRQAMAIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIIQCDL
CLKWRVLPSSIHYQEEEFLDIWICANNPNPLENSCHQTEHLPSIPLGTMSTVS-PSKNEK
EKQLRESIQRYQNRLEEMQPQKLQFIPATKITEFPTTCRTSAPKEYNKSQKIRSSSYDKL
KHESLSSSELSVTYRGQKR--NTEGSDSDI--ECISETKIMRKPAQKKVKPLQ--HKCPA
VPAESD--KVVELSQESQLS--NLSTVCGELKPKERPLEKLQASSRKMKRKKSQNLVQEC
TALIEVGNSNN-DPDIIWVSDNS--NSGVSLKEEKKEVP----LMNK-EKQELCNVAPEI
KRNSSLFNW-----ERS-VLNVPVEDLNPS--SGHKVNF--SVNEDCEVVSPLTKSSHSP
SVADTVRKLMSNLREILLYFFPEYQLPSEFGYT-SLEQLVASCEKQLEQCPEQTNKNLKM
CSNQIQNVYMVQYEKRLKRKM-QSITFDANRKEAVCKIYLGQCEEKRKSIEDKLKNLRVK
LTLVLQKFQLGSPASELEEIDSYLEALLKEDNLLFQNTLN-KVTIDLGHNLPLEKKERLQ
NN-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSWLTRTRESVTDDPQKFSIELSIIFKYSPFRNEAELMQQFDMIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDMLMAGAL--EDFPERWSFRAYTSVLYF
EPWMRIFIQAKRVQTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVEKAE-EAVKIAERV
LKQAQITVNQPDRT-----------SLSSAKDVLQKALEDVEAKHTILKVKQ----RELK
KARTLCLFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLRVMGQYLVQYCKDTGI-----------------
-------------SNRNLTRFWNEFGYQDN--KDVEKSLDSVQYQRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSINYQEKEFFDLWICANNPNILENSCHQAESLPSIPLGTMNRAS-PSKNEK
EKQLREAVQRYHNRLAEQQP-QPQFIPTRRIMEFTTTCRTSASKENTKTEKVRPWG-QDL
KQESLASFELSVSHRGQ-KK-NTEGTDSEV--EYIAEANIMKKSMQKKAKPQQ--QRHPA
ALPENV--RLAKRSQ---------------------------ASSREMSRKQNKNLVPEC
KALTEVETSDS-DPDIILVLDKS--GTDLSLKQEKKEVS----LMKK-EKQELCSDTPEM
KRNSSLPNR-----ESA-L----MEDLSPR--SGDSASF--SVYSGCGVTSSLTKSSQST
YVKETVRKLTSNLREILLYFFSEHRLPSEFGYT-SVEELMASFE--LEQCPEQTNKKLRM
GFSQIQHVYMVQYERELKRKI-QSIIYEANTRGVVNEIALGQCEAKRKLTEDKLNNLRVK
LAILLQKLQLGGPAGDLEQIDSYLEALLKEDNPLFQNALN-KVTTDTGHSLPLEKH----
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAVRLDVFSVDNETLQGGFMLCFLDDGCGMSPDE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDCILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESITDDPQKFFTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLIIYNLKLLLSGEPELDVRTDKEDILMAEAL--EEIPERRSLRAYTAVLYF
EPRMKIFIQAKRVQTKHLCYSLYKPRKYQY---TTSSFKGKFKTEVQKAE-EAVKRAELL
FKEVQAKV-KPDRI-----------ALSSTQDVLQKALQDLDTKHKTLRQKQ----RALR
KAGTLSLFFGVNTED-------QHQAGMFIYSNNRLIKLYEKVGPQLKMKSLLGAGVIGI
VNIPLEIMEPSHNKQEFLNVQEYSHLLKVMGQYLIQYCKDIGI-----------------
-------------SNRNLTLFWDEFKYQHS--KDTDSSLESLQWRRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

ILQCDL
CLKWRVLPSSFNYQEKGFPDLWICASNPNNLENSCNQIERLPSIPLGTMNRRP-PSKDER
ERQLQESVQRYQDKLVEAQPQKSQLIVTSKIPEFKSSCLSSALKEKSKLGRLKPSGADLT
QGSP-SSVKLSFIQRSQKR--STEDAHSDV--EFICMTKIPKKSVKKTVKYLQP-G-HAP
ALLENF--K---------------------------LEDTAQVSSWEIKKQQSESLVQAG
KAFTDA-ASSR-DPTVTVVWDQS--STKVSLKQE-KEEV----PLAKPDKQELCDDTPVV
KGDSSALHW-----KSL--PGVQMEDLSPR--SGHKI-N--SVSGDCQLPSSPM-PSQSM
SVEETARKLLSHLREILLYFVPEFQLSSEFECT-SVEELITN--PELERCPENINEKLKT
CFNQIQNIYMAQYEKRLKRKM-QSIVYEANRRGLLNQVFLGQCELKRKRTEEKLSDLRAK
LALLLQKFQLGGPAGDLQQIDAYLEDLLKEDRLST--TLH-EKSPESA------------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
NPRMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGALKNEVKKAE-EAVKIAEFI
LKEAQIKINQCDAT-----------SLSSAKDVLQRALEDVEAKQKNLREKQ----RELK
KAKTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQYQRRQAMGIPFIIQCDL
CLKWRVF---------------------------CHQIERLPSIPLGTMNTIS-PSKNEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NTEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRLPV
ALPENV--KLAERSQESQ--IANITSVWRAQPT-EEPLKNAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASSPS-SSQST
PVEETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKKKL-QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIK
LVLLLQKLQAGGPEGDLEQIDTHLEALLKEDNPLLQNNLN-KVTIDTRHRLPLEKK----
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLIIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSILYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFI
LKEAEIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNELGYQND--IDVEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQVERLPSIPLGTMSTIS-PSENEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMTSQQ--QRPPV
ALPENV--KLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGRKDRV--CVSGSDKVASLPA-SSQST
PVKETVRELKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISVGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNRLLQNNLN-KVTINTRHRLPLEKN-VKI
PEN------------------------------------------

--------------------------------------------MGDKYATLRRAQLHLD
FIHANSTTHSFLFGALAELLDNARDAGAARLDVFSVDNEKLQGGFMLCFLDDGCGMNPEE
AS-EIIYFGTSKKRSSALKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLTEVVVPIPSWLTRTRKSVTDDPQKLSTELSIIFKYSPFRNEAELMQQFDMIYGK
-----CGTLLVIYNLKLLLSGEPELDIKTDKEDILMAGAL--EDFPERWSFRAYTSVLYF
EPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEVI
LKEAQITVNQPDRT-----------SLSSAEDILQKALDDVEVKRKILKEKQ----RELK
KARTLCLFFGVNIEN-------RSQAGMFIYSNSRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVREYNHLLRVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYQND--KDKEKSLDSVQYQRRQAMAIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIIQCDL
CLKWRVLPSSVTYQEKEFFDLWICANNPNLLENSCHQAERLPSIPLGTTSSMS-PSKTEK
EKHLQEVVQRYQNRLADAQL-QPQFIPNR-ITESTTTCGTSTCKENTITQKVRPRG-DDL
KQGSLASFELRVSHRGW-KR-NTEGTDSDV--ECITDTKIMKKSPQKKAKPQQ--PRRPA
TLPENV--SPVQRSQKRQKANTST--SV-HLRPQRGHSEWAKASSWEINRKESQNLVQES
KALIEVETSNGDYPDIILVLDKS--DTEVSLKQEKKEVS----LMKK-EKQEPSSDTLEI
KRNSSLPNR-----ESS-VLSAQVEGLSPR--SGHGASF--SMRGSCHVVDLPTKSSPST
SVKETVRKLVSNLREILLYFFPEYQLPSEFGYT-SVKELAASFE--LEQCPEQTNKKLRM
CFNQIKNVYMVQYERELKRKM-QSIIYDANRRGVANEISLGQCEEKRKITEDKLNNLRVK
LTVLLQKLHLGSPAGDREQIDRYLEALLQEDNPLFQNALN-KVTADAGHGLPFERNRESK
SEVRK-------DNPF-----------------------------

--------------------------------------------MGDRYAALHRGQIHLD
YIQTNSTTHSFLFGALAELLDNARDAGATRLDVFSVDNEKLQGGFMLCFLDDGYGMSPEE
SS-DVIFFGMSRKRIAASRFIGHYGNGLK--SGSMRIGKDFILFTKKEETMTCIFLSQTF
CESEGLSEVVVPIPSWCSRTKESITE-PKKFSEELSIIQKYSPFKTEAELMQQFDKIYRK
-----SGTLVVIYNLKLMLNGEPELDIKTNKEDILIAGVL--EDLPERWSFRAYTSVLYF
DPRMRIFIQTKRVQTKHLSYCLYRPRKYLY---VTSSFKGVSKNEVKKAE-VAVKIAEQM
VREARYKIK-SVRT-----------GLPSAKDMLKKALEDAELKQKTLKEKE----KELK
KPKKLYLIFGVNIEN-------RSQDGMFIYSNCRLIKMHEKVGPQSKPGSLLGAGVVGI
VNIPLEVMEPSHNKQGFLDIKEYNHLLKIMGLYLVQYWKDTGF-----------------
-------------SNKNPILFWNEFGYQSS--KWLEKPLNSARYRRRQAREIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 641)

FIIQCDL
CLKWRVLPSSDDYKKRENLGNWTCADNPNLLENSCHRPEQLPSLPLGTMKQVSSSSENEK
EKQLRDSVQRYQNKLAEQQSQNSYFVPANKTTEFLPSSQASAPKEYPKSRTAMPRR-DAL
ERDTCSSSVVWTSHLSQKRR--WSRTDSTP--SHVFEGRIPETTVRGKVRVKQP--RHSE
N----I-----------------------------KINENSQVSSWVAKREPHQGFVKGS
KIIIDDEDSGS-DPDLIMFADEN--DAVMTLKREKEEPVQNKGLDSAEGKPYLCANTREI
KQNSSPLLL-----ESL-----STGDRSPC--TDKKENV---FMKESDVAFPLIKPPQST
CVKKTVEKLMAQLREILLYFHPHCKLSKDVDCK-SMEELMAM--CELENCPEQLNKKLQM
CCEQIWSVYMVQYEKKVRRKM-QSITQQANKTAMNNEAHYKQCEKQIKITENKLRSLRAK
VSTLLRNWNLST-SDDLENIDSYVEALLNEENLFLPDTLK-LVTRKSGQGLPSCEE----
---------------------------------------------

--------------------------------------------MGDKYAALRRAQLYLD
FIHANSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPLPSWLTRTREPFTDDPQKFSVELSIIYKYSPFKTETELMEQFSVIYGK
-----CGTLLIIYNLKLLLSGEPELDVRTDKEDILMAGPL--EEFPERWSFRAYTSVLYF
DPWMRIFIQAKRVKTKHLCYSLYSPRKYLY---VTSSFKGAFKNEVKKAE-EAVKSAELV
LKEVQFKVNQPDRN-----------SLSSAKDVLQKALEDVEEKHRNLKEKRXXXXXXXX
XXXXXXXXXXXXXXX-----------XXXXXXXXXXXXXXXXXXXXXXXXXXLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLKVMGRYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGQQSN--KDMEKSLDSIQYQRRQAMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCDL
CLKWRVLPSSTDYQDKEFLDVWICANHPNPLENSCHRMERLPSIPLGTMSTVS-PSKNEK
EKRLRASVQKYQNRLAEQQPQXXXXXXXXXX--XXXXXXXXXXXENTKTQKIRSLS-DDL
KHESPSCFELSVSHKSRKR--NTEETDSDV--EFVSETIVMK-SVKKKTKPQQ--QRHPA
GLPENI--TLAERSQKSHI-----------------------VSSWKMKRKQSINIVQEC
KALVDIESSNS-DSDIILILDED--DTDVSLKQEKMEVP----LTNK-EEQELSNDTSAV
KRNSSAPNW-----KSF--PRAPVGDVNPG--SGQKARP--CESSGYKADSLPTQSSQST
SVKETVRKLTSNLREVLLYFFPEYQLPPEFDHV-SLEELVTS--SELEQCPEQTNKKLKM
CFNQIQNIYMVQYEKNLKKKV-QSIIYDANTRGVLNEISLGKCEEKRKMTEDKLNDLRVK
LAALLEKLQLGGPAGNLEQIDTYLEALLKEDNLLFRNTLKIDTEI----L-FFRNNIRTS
QNE------------------------------------------

--------------------------------------------MAEKYSALHRAWLHLD
FLHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAARLDVFSVDNEKLQGGFTLCFMDDGCGMSPEE
AS-DIIHFGTPKKQLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVLFSQTF
CEGEGLSEVVVPMPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESVTDDAQKFSTELSIIYKYSPFQNEAELMEQFDMICGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAL--EGFPETWSFRAYTSVLYF
DPCMRIFIQAKKVQTKHLCYCLYRPRKYLY---ATSSFKGTLRNEVKKAQ-EAVKIAELL
LKEAQIKVSQPVRT-----------ASSSDQDILQKALEDVEAKHKNLKEKQ----RELK
KARTLSLFFGVNIEN-------PQQDGMFIYSNSRLIKMHEKVGPQLKQKSLLGTGVVGI
VNIPLEIMEPSHNKQEFLNIQEYKHLLKVMGQYLVQYSKDTGI-----------------
-------------SNRNLTLFWNEFRYQNN--KDAEKSLDSIQYQRRQAKAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLSSSTNYQKEEFLDTWICANNPNHLESSCHDTERLPTIPLGTLNLVS-PSRSEK
EKQLRESIQRYQNKLAEQQA-QFQFIPTGRITEFISTCSLSASKENSKTRKIRPPSGDNL
RHESLSSFELSLSQRNQKR--NEDSADSDI--EFISETKIIKKSTQKKMKLQE--KRPAT
ALPRNV--KPAEISQV-FSDFFLFTK----------------------------------
------YIIIHFKEIVFQVLDKN--DADVSLKKEKKEVP----LINK-GKKNSV------
--YIDLDLA-----VL-------------------------------------------T
SVKETVRKLLSNLREILLYFVPKYLLSSEFNCT-SVEELIAS--IELEQCPEQTNKKLKI
CFNQIQNVYMVQYEKNMKRKI-QSIIYDANRRAILNEVSLIRCEQKRKVSEDKLNNLRVK
LAALLQKLQLGGPANDLEQIDAYLEGLLEDDRFLFQNTLK--------------------
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAVRLDVFSVANETLQGGFMLCFLDDGCGMSPDE
AP-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPSWTT

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRKSITDDPQKFFTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLVIYNLKLLLSGEPELDVETDKEDILMAGAL--EELPERRSFRAYTAVLYF
DPRMRIFIQAKRVQTKHLCYSLYKPRKYQY---ATSSFKGKFKTEVKEAE-EAVKMAELR
FKELQAKVNQPNTS-----------SLSSAKDELQKAQEDVETKHKHLREKQ----RALR
KARTLSLFFGVHIED-------QNQSGMFIYSNNRLIKMHEKVGPQLKMKSLLGAGVIGI
VNIPLEIMEPSHNKQEFLNVQAYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLAVFWDEFRYQHS--KDLDRSSGSLQWQRRKALAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

ILQCDL
CLKWRVLPFLSNYQE-EFPDMWICANNPNNLGNSCNQLEHLPSIPLGTMSRRP-PSKDEK
EKQLQESVQRYQNRLAEAQPQKPQLITMSRIPEFKASNLSSAAKEKSKLGRMGPLVVDGM
QGNPPSFGECSSIQRGQKR--STEDADSDV--EFVCMTKVLKRTVKKKVKHQQP-S-YTP
ALSENL--K---------------------------SGEASQVFSWEAKRKQSENLAQEC
KASMEVETVSG-DPAVILVWEKT--STKVSLKQER-TEI----PLPKTEKQELCDETLVM
KGNPSTLNW-----ESL--PGMQMEDLSPC--SGHKV-S--SDNGDHQLS-SLM-PSQST
AAKETARKLMSNLKEILLYFIPEFQLSSEFECT-SLEELITS--PELERCPETTNKKLKT
CLNKIQDIYMVQYEKRLKRKM-QSLIYETNRRRLLNEVFLGQCELKRKKTEEKLNDLRAK
LALLLQKLHLGGPAGELQQIDAYLEALLKEDRLPD--TLN-GRTLESGQ-----------
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAVRLDVFSVDNETLQGGFMLCFLDDGCGMSPDE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDCILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESITDDPQKFFTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEAP--EEIPERRSFRAYTAVLYF
EPRMKIFIQAKRVQTKHLCYSLYKPRKYQY---TTSSFKGKFKTEVQKAE-EAVKRAELL
FKEVQAKVNQPDRI-----------ALSSTQDALQKALQDVDTKHKSLRQKQ----RALR
KARTLSLFFGVNTED-------QHQAGMFIYSNNRLIKMYEKVGPQLKMKSLLGAGIIGI
VNIPLETMEPSHNKQEFLNVQEYNHLLKVMGQYLIQYCKDIGI-----------------
-------------SNRNLTLFWDEFKYQHS--KDTDSSLESLQWRRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

ILQCDL
CLKWRVLPSSSNYQEKGLPDLWICASNPNNLENSCNQIERLPSIPLGTMNRRP-PSKDER
ETQLQESVQRYQDKLVEAQPQKSQLTVTSKIPEFTSSCLSSALKEKPKLGRIKPSGADLT
QGSP-SSVKLSFIQRSQKR--STEDAHSDV--EFICMTKIPKKSVKKTVKYLQP-G-HAP
ALLENL--K---------------------------LEDTAQVSSWEIKKQQSESLVQAG
KASTDA-ASSR-DPTVTVVWDQS--STKVSLKQEEEEEV----PLIKPDKQELCDDTPVV
KGNSSALHW-----KSL--PGVQMEDLSPR--SRHKI-N--SVSGDCQLPASPM-PSQSM
SVEETARKLLSNLREILLYFVPEFQLSSEFECT-SVEELITN--PELERCPENINEKLKT
CFSQIQNIYMAQYEKRLKRKM-QSIVYEANRRGLLNQVFLGQCELKRKRTEEKLSDLRAK
LALLLQKLQL--------------------------------------------------
---------------------------------------------

--------------------------------------------MDDRYPALRRAQLRLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKDEVKKAE-EAVKIAESI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
TARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDVEKPLNSIQCQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQIERLPSIPLGTMSTIS-PSKNEK
EKQLRESVIKYQNRLAEQR-PQPQFIPVDEIT-ATSTCLTSAHKENTKTQKIRLLG-DDL
KHESLSSFELSASHRGQKR--NIEETDSDV--EYISETKIMKKSMEENMNSQQ--QRIPV
ALPENV--KLAERSQRSQ--IANITTVWRAQPT-EGCLKNAQATSWEMKRKQSLNFVEEC
NVLTEDE-NKS-DSDIILVSDKS--NTDVSLKQEKKEIP----LLNQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGHIARV--SVSGSCKVASSPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEQMNEKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIRNEISLGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNLLFQNNLN-KVTIDARHRLPLEKN-EKT
SEN------------------------------------------

--------------------------------------------MDDRYPALQRAQLRLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKDEVKKAE-EAVKIAESI
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
TARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDVEKPLNSFQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 638)

IIQCDL
CLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVECLPSIPLGTMSTIS-PSKNEK
EKQLRESVIKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSAHKENTKTQKIRLLG-DDL
KHESLSSFELSASRRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRIPV
ALPENV--KLAERSQRSQ--IANITTVWRAQPT-EGCLKNAQAASWEMKRKQSLNFVEEC
KVLTEDE-NTS-DSDIILVSDKS--NTDVSLKQEKKEIP----LLNQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGHIARV--SVSGSCKVASSPA-SSQST
PVKETVRKLKSKLREILLYFFPEHQLPSELEEP-A-------LSCELEQCPEQMNKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNLN-KVTIDARHRLPLEKN-EKT
SEN------------------------------------------

--------------------------------------------MGDKYATLRRAQLHLD
FIHANS

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 125)

TTHSFLFGALAELLDNARDAGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-D

ENSGT00530000062983_1_Linker_0_1 (125, 593)

IIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEEGLSEVVVPMPSWLTKNREPVIDDPQKFSTELSIIYKYSPYKTEAELMRQFDIIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAEAL--EDFPERWSFRAYTSVLYF
DPRMRIFIQAKKVKTKHLCHCLYKPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAELV
LKDARIRVNQPDRTS----------LPSPAKDVLQKALEDVEAKHKILKEKR----RELK
TARTLSLFFGVNTEN-------RNHAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVIGI
INIPLEVMEPSHNKQEFLNVQEYNHLLRVMGQFLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYQNN--KDTERSLESIQYQRRQAMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCDL
CLKWRVLPPSTDYLEKELLDAWICANNPNLSENSCHQAERLPPIPLGTMSTVS-LSKNEK
EKRLQESVRRYQDQLAEQQ-LELQFIPKSRIAESTTICRISASKENTKPRKIRPSG-YDL
KHESFASFELSAAQRS-WKS-NTEGTDSDV--EFVSETKVMKSTRKK-E--EPQ-QRHPA
ALPEKV--RLTERSQEIA--VAHQQNVWRAQPTE-RPPKNMPASSWEMKRKENQNLVQEC
QGLIEVETSNS-DQDLILILDQS--DNNVFLKHEKKEVP----LMKK-EKQELCSDIAEI
KRNSSLPNW-----KRL--LNIPVEDLGPG--SGHRARV--AVSSGCEVGSSLTKSSQSP
SVKETVRKLASNLWEIILYFFPEYQLPSEIGYS-SVEEFVAS--LELEQCTEQTNRKLKM
CFQQIQDVYMAQYAKKLKRTT-QSIIYDANRRGVINEISLVQCEQKRKITEDRLNNLRVK
LAALLQKLQLGGPVGDMEQIDSYLEALLKEDHLL-GNTFN-KGSTDAGHSLPLENNESTS
QN-------------------------------------------

--------------------------------------------MGDKYATLLRAQLHLD
FIHANSTTHSFLFGALAELLDNARDAGAARLDVFSVDNEELQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSWLTRTRESVTDDPQKFSTELSIIYKYSPFKTEAELMQQFNVIYGK
-----CGTLLVVYNLKLLLSGEPELDVKTDREDILMAGAL--GDFPERWSFRAYTSVLYF
DPWMRIFIQAKRVRTKYLCYCLYRPRKYLY---VTSSFKGAFKCEVKKAE-EAVKRAELI
LKEAQIKVNHSDRT----------PLSSSAKDVLQKALEDVKAKQKVLQEKQ----RELK
KARTLTLFFGVNIEN-------RSQAGMFIYSSNRLIKMHEKVGPQLKLKSLLGEGVVGI
VNIPLEIMEPSHNKQEFLNVHEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYPDN--KDMEKSSDSVQYQRRQAMAIPC

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 640)

MIQCDL
CLKWRVLPPSTNYQEKEFFDIWICANNPNLSENSCHRTEHLPSIPLGTMSTVS-QSKNEK
DKQLQESVQRYQNQLVEPR-QQPQFIPVNRITELTSPFQASTSKGNKKIQRIRPSS-DDW
KHESLSSFELLVNHRG-WEK-NTEGADSDV--EYISETEIMKKSGQKKVKPQQ--QMYPA
VPLENV--KLASRDQ-KSQ---------IANISTEGLLKNTSMASWEMKRKRSQNL----
-ASIEVETSNS-NSDIIPILDES--DTDVPLKQEKKEVS----LMKKEEKQELCSDTPEI
NRNSSSPNW-----ESLFLPSMPVEDLNPS--SGYKARV--SVSGDCKVASALTESSQST
SVKETVRKLTSNLREILLYFFPEYQLPSEFGQA-SLEELTAC--SELEQCPEQTNKKLKM
CFNQICDVYMVQYEKKLKRRI-QSVICDANKRAVVNEVSLGQCEKKRKLTEDKLNKLRVK
LAVLLQKLQLGGPAGDLEQIDAYLEALLKEDNLLFQ----NKVTTDTGHCLLLEKKESIS
QN-------------------------------------------

--------------------------------------------MGDKYAALRRARLHLD
FIHANS

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 125)

TTHSFLFGALAELLDNARDAGAARLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-D

ENSGT00530000062983_1_Linker_0_1 (125, 593)

IIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLNEVVVPIPSWLTRTKESVTDDPQKFSTELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVVYNLKLLLSGEPELDVKTDKEDILMAGAL--EDFPERWSFRAYTSVLYF
DPWMRIFIQAKRVQTKYLCYCLYRPRKYLY---VTSSFKGTFKNEVKKAE-EAVKIAELT
LKEVQIEANHSDRTS----------LSSPAKDVLQKASEDVKAKHKILQEKR----RELK
KARTLSLFFGVNIEN-------QSQAGMFIYSNNRLIKMHEKV-PQLKLKSLLGAGVVGI
VNIPLEIMVPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYANN---DVERSLDSVRYHRRQAMSI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCDL
CLKWRVLPSSTHYQEKESFDIWICANNPNLQENSCCQMERLPSIPLGTMNTVP-PSKTEK
EKQLRESVQRYQNRLAEQ-PRQPQFIPTSRITEFTTTCQTSAPKXXXXXXXXXXXX-XXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXYAERVN---S-QQRHA
ALLENV--SLAERSQKSQ----------IASISIEELLRNTWASSWEMKRKQSQNPVQKC
KVLIEVETGNS-NLDIIQILDEN--DTDVLLKEEKKEVS----FMKK-EKQELCSETSEI
KRSSSSPNR-----ESLFLPSMPVEDLNPR--SGYKARV--SVGGVCKVASSLTESSQST
SVKETVRKLTSNLREILLYFFPEYQLPSEFGHR-SLEELTASSEXX--XXXXXXXXXXXX
XXXXIQNVYMVQYEKNLRRKM-QSIIFDSNRRGVLNEVSLGQCEKKRRAAEDSLNDLRAK
LAVLLQKLQLGGPAGDLEQIDSYLEALLKEDNLLFHNALN-KGTTDSGHNLPSEKKESTS
HT-------------------------------------------

--------------------------------------------MDGKYGPLLRARLHLD
FIHVNSTT

PF13589 // ENSGT00530000062983_1_Domain_0 (69, 196)

YSFLFGALAELMDNARDAGAARLDVFSVDNEELQGGFMLCFLDDGCGMSPEE
AS-DIISFGTSKKRLSTWKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCLFFSQTF
CEGEGLTEVVVPIPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTGSRKSVTDDPQKFSTELSIIYKYSPFKTEAELMEQFDMICGR
-----CGTLLVIFNLKLLLSGEPELDIKTDKEDILLTDAL--EGLPERWSLRAYASVLYF
EPRMRIFIQAKRVQTKHLCYSLYKPRKYHY---VTYSFKGKLKNEVKKAE-EAVKAAEII
LKEIQLKANQPDRIS-----------SLSAKAALQKAVDAAEATHRDLKEKQ----RELK
KARTLSLVFGVSLEN-------RSQAGMFIYSNNRLIKMHERVGPQLKAKSLLGTGVIGI
VNIPLTIMEPSHNKQEFLNAQEYNRLLRVMGQHLVQYCKDTGI-----------------
-------------SNRNLSLFWNELRNQ-N--KDMERSSEFIQYQRRQAVAIPL

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IVQCDL
CLKWRVLPLSTQYREEDFLGMWICANNPNKSENSCHQVERLPSIPLGTRSAAP-SSQTEK
DRHLRECVQRYQEKLAEPRPQVSC-SPSS--PRRCSSCLHRV---AA--------PIDSL
PS----PFLPTL-SSSFDQKRDAESAESDV--EFVAKTETAKSSRKKQRSL------GPR
GLGAALRTSTARRPQVRSFSC---------------------------------------
----------------------------------------------------------FL
STKPTIIHL-----VSMSLPSVPVEDLSPG--LEPD-VS--SVSDSCQITSSPVMSSQST
SIKETVRKLMSNLREILLYFVPESQLTSAFNYV-SVEELIGS--PQMEQSPEKTNEKLKV
CFSEIENILMVQYERNLKRRL-QSMIYDSNRRGLLNEVYLIQCEHKRKLAEEKLNNLRAK
LAVLLQKLQLGGPAGDLEQMDAYVEALLKSNTLP--------------------------
---------------------------------------------

--------------------------------------------MDDRYAGLRRAQLHLN
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 197)

FGALAELLDNARDAGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DVIYFGRSKKRLSTLKFIGQYGNALK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEEGLSEVVVPIPSW

ENSGT00530000062983_1_Linker_0_1 (197, 595)

LTRTRESVTDDPQKFSVELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLNLLLNGEPELDVKTDTEDILMAGAL--EDFPERWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLGYCLYRPRKYLY---VSSSFKGAFKNEVQKAE-EAVRIAEFV
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDAKAKQKNLKEKQ----RALK
KARTLSLFYGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGV
VNIPLEIMEPSHNKQEFLNVREYNHLLKVMGQYVVQYCKDTGI-----------------
-------------NNRSLTLFWNEFGYQND--INIDRPLNSIQCQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTHYQEKEHFDIWICANNPNLLENSCNQIERLPSIPLGAMSTVS-PSKNEK
EKQLRESVLKYQNRLAEEQ-PQ----------------------ENNKTQKIRLLG-DDL
KHESLSFFQLSVSHRGQKI--NREETDSDV--EYISETKIMKKSMEEKMNSQQ--QRLPV
ALPENV--KLAERS---Q--IANITSVWRAQLT-EGPQKNAQATSWKMKRKQSLNLVEEC
KVLTEDENSKS-DPDIILVSDKS--NTDVSLKQEGKAIR----LINQ-EKQELCNDVLAM
ESISSLPSW-----KSL--PNVPVEDVDLS--SGHKARV--SVSDGCTVASTPT-SSQST
SVKEPVRKLMSKLRETLLYFFPEYQLPSELEEP-A-------LSCELEQCPEQINKKLKM
CFNQIQNTCMTQYEKKLKRKI-QSVIYASNTRGICNEISLGQCEGKRKTSEDELKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNLLFQNN----------------------
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILVAGAL--EDFPARWSFRAYTSILYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFV
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------TNRNLTLFCNEFGCQND--IDMEKPLNSIQHQRRQAMGIP

PF07496 // ENSGT00530000062983_1_Domain_1 (594, 640)

FIIQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQVEHLPSIPLGTMSTIS-PSKNEK
EKQLRESVLKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSADKENTKTQRIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRPPV
ALPENV--KLAERSQKSQ--IANITSVWRAQPT-EEALKDAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSKS-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KRL--LNVPMEDVNLS--SGRKDRI--CVSGSDKVASLPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHINQKLKM
CFNQVQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDN-LLQNNLN-KVTIDTRHRLPLEKK-GKD
S--------------------------------------------

------------------------------------------------------------
-----------------------------RLDVFSVDNEKL

PF13589 // ENSGT00530000062983_1_Domain_0 (102, 196)

QGGFTLCFMDDGCGMSPEE
AS-DIIHFGTPKKQLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVLFSQTF
CEGEGLSEVVVPMPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESVTDDAQKFSTELSIIYKYSPFQNEAELMEQFDMICGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAL--EGFPETWSFRAYTSVLYF
DPCMRIFIQAKKVQTKHLCYCLYRPRKYLY---ATSSFKGTLRNEVKKAQ-EAVKIAELL
LKEAQIKVSQPVRT-----------ASSSDQDILQKALEDVEAKHKNLKEKQ----RELK
KARTLSLFFGVNIEN-------PQQDGMFIYSNSRLIKMHEKVGPQLKQKSLLGTGVVGI
VNIPLEIMEPSHNKQEFLNIQEYKHLLKVMGQYLVQYSKDTGI-----------------
-------------SNRNLTLFWNEFRYQNN--KDAEKSLDSIQYQRRQAKAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLSSSTNYQKEEFLDTWICANNPNHLESSCHDTERLPTIPLGTLNLVS-PSRSEK
EKQLRESIQRYQNKLAEQQA-QFQFIPTGRITEFISTCSLSASKENSKTRKIRPPSGDNL
RHESLSSFELSLSQRSQKR--NEDSADSDI--EFISETKIIKKSTQKKMKLQE--KRPAT
ALPRNV--KPAEISQV-FSDFFLFTK----------------------------------
------YIIIHFKEIVFQVLDKN--DADVSLKKEKKEVP----LINK-GKKNSV------
--YIDLDLA-----VLL--PSVPTEG--LR--SGHETRV--SVSGSSKIASLPTLSSQST
SVKETVRKLLSNLREILLYFVPKYLLSSEFNCT-SVEELIAS--IELEQCPEQTNKKLKI
CFNQIQNVYMVQYEKNMKRKI-QSIIYDANRRAILNEVSLIRCEQKRKVSEDKLNNLRVK
LAALLQKLQLGGPANDLEQIDAYLEGLLEDDRFLFQNTLK--------------------
---------------------------------------------

-----------------------------MAGLSTLPFGSPPQQGREKTPEVASAGCCLL
LFTFMGTTHGFLF

PF13589 // ENSGT00530000062983_1_Domain_0 (74, 194)

GALAELLDNARDAGAGRLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIINFGTHRKHLPTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVLFSQTF
CEGEGLSEVVVPM

ENSGT00530000062983_1_Linker_0_1 (194, 596)

PSWLTRTRESVTDDPQKFSTELSIIYKYSPFQEEAELMQQFDVIYGK
-----CGTLLVVYNLKLLLSGEPELDVKTDKEDILMAGAL--EGFPETWSFRAYTSVLYF
DPCMKIFIQAKKVQTKHLCYCLYKPRKYLY---ATSSFKGALKNEVKKAQ-EAVKIAELI
LKEAQVEVNQPDRA-----------ASSSASDILEKALEDVEAKRKNLKEKQ----RELK
KAGTLSLFFGVNVEN-------PSQGGMFLYSNSRLIKMHEKVGPQLKQKSLLGSGVVGI
VNIPLEIMEPSHNKQEFLNIQEYNHLLRVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFRNEFGSWNN--TDAEKPLDSLPHQRRQALTIPVI

PF07496 // ENSGT00530000062983_1_Domain_1 (596, 639)

MQCDL
CLKWRVLPSSTNYQKREFLDTWICADNPNCSDNSCDDIERLPTIPLGTLSMVS-PSRSEK
EKQLKESIQRYQNKLLEQQA-Q----------------------ENSKTQKIGPPSYDNL
RHESLLSFKLSLSQRSQKR--NAD-ADPDV--ELISEIKVVKKSVHKKMKSQE--QRTAA
ALPRNV--KPAEIAQV-L------------------------------------------
--------------------DKN--DADVSLKKEKKEAP----VLSK-GKQKLYRDAPAT
EGNPSSPQL-----KSL--PKEAVEDLSVR--SGHKATV--PVSGWSKIASLPTTSSPST
TVKETVKKLIAILREILLYFAPKYLQSSEFNYT-AVEELIAS--VELARSPEQANKKLEL
CFNQIQNVYMAQYEKNMKRKI-QSITCDASRRAILNEVSLLHCEQRRKRAEDKLNDLRVK
LAALLQTLQLGGPAGDLEQTDAYLEGLLQDDKLLFQNTSK--------------------
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAVRLDVFSVANETLQGGFMLCFLDDGCGMSPDE
AP-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPSWTT

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRKSITDDPQKFFTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLVIYNLKLLLSGEPELDVETDKEDILMAGAL--EELPERRSFRAYTAVLYF
DPRMRIFIQAKRVQTKHLCYSLYKPRKYQY---ATSSFKGKFKTEVKEAE-EAVKMAELR
FKELQAKVNQPNTS-----------SLSSAKDELQKAQEDVETKHKHLREKQ----RALR
KARTLSLFFGVHIED-------QNQSGMFIYSNNRLIKMHEKVGPQLKMKSLLGAGVIGI
VNIPLEIMEPSHNKQEFLNVQAYNHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLAVFWDEFRYQHS--KDLDRSSGSLQWQRRKALAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

ILQCDL
CLKWRVLPFLSNYQE-EFPDMWICANNPNNLGNSCNQLEHLPSIPLGTMSRRP-PSKDEK
EKQLQESVQRYQNRLAEAQPQKPQLITMSRIPEFKASNLSSAAKEKSKLGRMGPLVVDGM
QGNPPSFGECSSIQRGQKR--STEDADSDV--EFVCMTKVLKRTVKKKVKHQQP-S-YTP
ALSENL--K---------------------------SGEASQVFSWEAKRKQSENLAQEC
KASMEVETVSG-DPAVILVWEKT--STKVSLKQER-TEI----PLPKTEKQELCDETLVM
KGNPSTLNW-----ESL--PGMQMEDLSPC--SGHKV-S--SDNGDHQLS-SLM-PSQST
AAKETARKLMSNLKEILLYFIPEFQLSSEFECT-SLEELITS--PELERCPETTNKKLKT
CLNKIQDIYMVQYEKRLKRKM-QSLIYETNRRRLLNEVFLGQCELKRKKTEEKLNDLRAK
LALLLQKLHLGGPAGELQQIDAYLEALLKEDRLPD--TLN-GRTLESGQAKDKEW-----
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 195)

FGALAELLDNARDAGAVRLDVFSVDNETLQGGFMLCFLDDGCGMSPDE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDCILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIP

ENSGT00530000062983_1_Linker_0_1 (195, 595)

SWLTRTRKGITDDPQKFFTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLIIYNLKLLLSGEPELDVTTDKEDILIAEAP--KEIPERWSFRAYTAVLYF
EPRMKIFIQAKRVQTKYLCYSLYKPRKYQY---TTSAFKGKFKTEVQKAE-EAVKMAELL
FKEVQAKVNQPDRI-----------ALSSTEDVLQKALEDVDTKHKNLRQKQ----RALR
KARTLSLFFGVNIET-------QSQAGMFIYSNNRLIKMYEKVGPQLKMKSVLGAGIIGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLKVMRQYLMQYCKDTGI-----------------
-------------SNRNLTQFWDEFKYQHS--KDTDSSLESLQWRRGEAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

MLQCDL
CLKWRVLPSSSSYQEKEFPDLWICANNPNNPENSCNQIERLPSIPLGTMDRRP-PSKDER
EKQLQESVQRYQDRLVEAQPQKSQLTVTSKIPEFKSSCLSSACKEKSKLGRIKPSGADLT
QGSP-SSVELSFIQRSQKR--STEDSDSDV--EFVCMTKIPKKSAKKTVKNLQP-G-HSP
ALLENL--K---------------------------LEDTAQVSSREIKKQQSENLVQAC
KASTDVEASSR-DPAITVVWDQS--STKVSRRQEKKEEA----PLAKPDKQELCDDTPVV
KGNCSALHW-----KSL--PGVQMEDLSPR--SGHKV-S--SVTGDCQPPSSPM-PSQSM
SVEETARKLLSNLREILLYFVPEFQLSSEFECT-SVEELITN--PELERCPENINKKLKT
CFNQIQNIYMAQYERRLKRKM-QSIVYEANRRGLLNEFFLGQCELKRKRTEEKLNDLRAK
LALLLQKLQLGGPAGDLQQIDTYLEDLLKEDHLRT--ALH-EKSPESGQAEDTGH-----
---------------------------------------------

--------------------------------------------MGDKYPALLRAQLHLD
FIHANSTTHSFLFGALAELLDNARDAGAARLDVFSVDNEELQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSWLTRTRESVTDDPQKFSTELSIIYKYSPFKTEAELMQQFNVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDREDILVAGAL--GDFPERWSFRAYTSVLYF
DPWMRIFIQAKRVRTKYLCYCLYRPRKYMY---VTSSFKGAFKCEVKKAE-EAVKRAELI
LKEAQIKVNYSDRT----------SLSSSAKDVLQKALEDVKAKQKILQEKQ----RELK
KARTLTLFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVHEYNHLLKVMGQYLVQYCKDTRI-----------------
-------------SNRNLTLFWNEFGYPDN--KDMEKSSDSVQYQRRQAMAIPC

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 640)

MIQCDL
CLKWRVLPPSTDYQEKELFDIWICANNPNLSENSCHRTEHLPSIPLGTTSIVS-QSKNEK
DKQLRESVQRYQNQLVEPR-QQPQFIPVNSITEFTSPCQASASKGNKKIQRIRPSS-DDL
KHESLSSFELLVNHRG-WKK--TEGSDSDV--EFISETKIMKKSGQKKVKPQQ--QRYPA
VPLENV--KLASRDQRKSQ---------IANISTEGLLKNTSMASWEMKRKRSQNL----
-PSIEAETSNS-NSDIIQILDES--DTDVPLKQEKKEVS----LMKKEEKHELCSDTPEI
KRNSSSPKW-----ESLFLPSMPVEDLNPS--SGYKARV--SVSGGCKVASSLTESSQST
SVKETVRKLTSNLREILLYFFPEYQPPSEFGQT-SLEELTAS--SELEQCPEQTNKKLKM
CFNQIRDVYMVQYEKKLKTKI-QSVICDANQREMVNEVSLGQCEKKRKLTEDKLNKLRVK
LAVLLQKLQLGGPAGDLEQIDAYLEALLKEDNLLFQKAFVNKVTTDTGHRLLLEKKENIS
QN-------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNEKLQGGFTLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTMKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEKESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAVELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPVRWSFRAYTSVLYF
NPRMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFV
LKEAQIKVNQCDRT-----------SLSSAKDVLQRALEDVEAKQKNLKEKQ----RELK
KARTLSLFYGVNIEN-------QSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVIGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGV-----------------
-------------NNRNLTLFCNEFGYQND--IDMEKPLNSIQCQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTNYQEKEFFDVWICANNPNRLENSCHQIECLPSIPLGTISTIS-PSKNEK
EKQLRESVLKYQDRLAEQQ-PQPQFIPVDEIT-VTSTCLTSASKENTKTQKIRLLG-DDL
KHESLSSFELSVSHRGQKR--NIEETDPDV--EFISETKIVKKSMEEKMNSQQ--QRIPV
ALPENV--KLAERSQKSQ--IANITSVWRAQPT-EGPLKNAQAASWEMKRKQNLNFVEEC
KVLIEDENSKS-DSDIILVSDKS--STDVSLKQEKKEIP----LLNQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLG--SGCKARV--SVSGSCKVASSPT-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEQINKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISLGQCENKRKISDDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNLLF-NNLN-KVTIDTRHRLPLEKN-EKT
PEN------------------------------------------

------------------------------------------------------------
------------------------DAGATRLDVFSVDDEKLQGGFMLCFLDDGYGMNPEE
AS-DVIFFGMSKKRIAASRFIGHYGNGLKXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX
XXXXXXXXVVVPIPSWSSGTKKSITD-PKKFAEELSIIYKYSPFKTEAELMQQFDKIYRK
-----SGTLVVIYNLKLMLNGEPELDIKTNKEDILIAGVLEXXXXXXXXXXXXXXX--XX
XXXXXXXXXXXXXXXXXXXXXXXXXXKYLY---VTSSFKGASKNEVKKAE-VAVKIAEQL
VKEAKFKINRSIQT-----------GLSSAKDMLKKALEDAEVKQKVLKEKE----XXXX
XXXXXXXXFGVNIEN-------RSQDGMFIYSNSRLIKMHEKVGPQLRL-TLLGAGVVGI
VNIPLEVMEPSHNKQGFLNVKEYNHLLKIMGLYLVQYWKDTGFXXXXXXXXXXXXX----
--------------------------XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXX

PF07496 // ENSGT00530000062983_1_Domain_1 (600, 642)

L
CLKWRVLPSADDYKKRENLVNWTCASNPNLLENSCHRPEQLPSFPLGTMKQLS-SSEDEK
EKQLRDSVQRYQNKLVEQQSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXX-XXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX-XXXXX
XXXXXX--XXXXXXXXXXX----X---XXXX----XXXXXXXXXXXXXXXXXXXXXXX--
-XXXXXXXXXX-XXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXKLKLYADTPEK
A-DSSPLNL-----ESLFMFSPSTDDLSPC--PWKKEEE---FMGRC---VPLVTPPQST
CVKETVGKLMAQLXXXXXXXXXXXXXXXXXXXX-XXXXXXX-------XXXXXXXXXXXX
XXXXXXXXXXXXXXXKVRRKM-HSLTQQANKTAMNNEAHHKQCEKQITITENKLKSLQAK
VATLLLEL--RTASDDFENIDSYIEALLNEENLFLPNTLK-LVTRKSRKALPFCEEKKH-
---------------------------------------------

--------------------------------------------MGDRYAVLRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNALK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEEGLSEVVVPMPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESVTDDPQKFSMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLNLLLNGEPELDVKTDREDILMAGAL--EDFPERWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLGYCLYRPRKYLY---VTSSFKGAFKNEVQKAE-EAVKIAEFV
LKEAQMKVNQCDRT-----------SLSSAKDVLQRALEDAKAKQKNLKEKQ----RELK
KARTLSLFYGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVREYNHLLKVMGQYVVQYCKDTGI-----------------
-------------NNRNLTMFWNEFGYQND--INIERPLNSIQFQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTHYQEKEFFDIWICANNPNLLENSCHQIERLPSIPLGAMSTVS-PSKNEK
EKQLRESVLRYQNRLAEQQ-PQPQFIPVDKISELTSTCITSATKENNKTQKIRLLG-DDL
KHQSLSFFQLSVSHRGQKI--NIEETDPDV--EHISETKIMKKSMEEKMNSQQ--QRLPV
ALPENV--KLAERSQKIQ--IANITSVWRAQLT-GGPQKNAHATSWKMKRKQSLNLVEEC
QVLTEDENSKS-DPDIILVSDKS--NTDVSLKQEKKEIP----LINQ-EKQELCNDVLAT
KSISSLPSW-----KSL--PNVPVEDVNLS--SGHKARV--SVSGGCKVASMPM-SSQST
PVKEPVRKLMSKLRETLLYFFPEYQLPSELEEP-A-------LSCELEQCPEQINKKLKM
CFNQIQNTCMAQYEKKLKRKI-QSVIYDSNTRGIRNEISLGQCEGKRKISEDELKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNLLFQNN-N-KVTIDTRHRFFLEKKNENT
PEN------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAARLDVFSVDSETLQGGFMLYFLDDGCGMSPDE
AP-DIIYFGTSKKQLSTSTFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPSWST

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVADDPQKFFTELSIIYKYSPFKNEAELMQQFDMIYGR
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAEAL--EDLPERRSFRAYTAILYF
DPRMRIFIQAKRVQTKHLYYSLYKPRKYQY---APSSFKGKFKTEVKEAE-EAIKMAELR
FKELQVKGSQPNRI-----------SLSSTEDGLQRAREDVEAKHKNLREKQ----RALR
KARTISLFFGVHIED-------QRQAGMFIYSNNRLIKMHEKVGPQLKMKSLLGAGVIGI
VNIPLEIMEPSHNKQEFLNVQEYSHLLKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWDEFKYQHS--KDMDRSLESLQCRRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 640)

ILQCDL
CLKWRVLPSPSNYEE-EFPDMWICANNPNNLENSCNQPEHLPPIPLGTMSRRP-PSKDET
ERQLQESVQRYQNRLADIQPQTPQFIAVSRIPEFKPSCLSSEQKEKSTLGRLRPSVVDRI
QGTPPSSVQFSSSQRVLKR--SPEDADSDV--EFVCMTKIRKRAVRRSVKHQQQ-S-HVP
DLSENL--K---------------------------LMEASQVSSWETMKKQSENLVQEC
KASPEVETSSR-DPAVILVWDET--STEVSLKQER-MEV----PLPKTEKQELCDDTLVM
KRNPSALNW-----KRG--P---VEDLSPH--FGHKV-S--SVNGNCQLS-SLM-PSQSI
STKETARKLMANLREILLYFIPEFHLSSEFECT-SMEELLTN--PELEQCPESMNEKLKV
CFNKIQNIYMVQYERRLKRKM-QSIIYEANRREMLNEVFLGQCEQKRKKTEDKLNNLRAK
LSSLLQKLQLGGPAGDLEQIDAYLEALLKEDHLPT--TLN-RRTLESGQ-----------
---------------------------------------------

--------------------------------------------MGDKYPALLRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 197)

FGALAELLDNARDAGAARLDVFSVDNEELQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLSEVVVPIPSW

ENSGT00530000062983_1_Linker_0_1 (197, 595)

LTRTRESVTDDPQKFSTELSIIYKYSPFKTEAELMQQFNVIYGK
-----CGTLLVIYNVKLLLSGEPELDVKTDREDILVAGAL--GDFPERWSFRAYTSVLYF
DPWMRIFIQAKRVRTKYLCYCLYRPRKYMY---VTSSFKGAFKCEVKKAE-EAVKGAELI
LKEAQIKVNYSDRT----------SLSSSAKDVLQKALEDVKAKQKILQEKQ----RELK
KARTLTLFFGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVHEYNHLLKVMGQYLVQYCKDTRI-----------------
-------------SNRNLTLFWNEFGYPDN--KDMEKSSDSVQYQRRQAMAIPC

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

MIQCDL
CLKWRVLPPSTDYQEKELFDIWICANNPNLSENSCHRTERLPSIPLGTMSTVS-QSKNEK
DKQLRESVQRYQNQLVEPR-QQPQFIPVNRITEFTSPCQASTSKGNKKIQRIRPSS-DDL
KHESLSSFELLVNHRG-WKE--TEGSDSDV--EYISETKIMKKSGQKKVKPQQ--QRYPA
VPLENV--KLASRDK----------------------------ASWEMKRKRSQNL----
-TSIEVETSNS-NSDIIQILDES--DTDVPLKQEKKEVS----LMKK-EKQELCSDTPEI
KRNSSSTKW-----ES-----MPVEDLNPS--SGYKARV--SVSGGCKVASSLTESSQST
SVKETVRKLTSNLREILLYFFPEYQLPSEFGHT-SLEELTAS--CELEQCPEQTNKKLKM
CFNQIRDVYMVQYEKKLKTKI-QSVICDANQREMVNEVSLGQCEKKRKLTEDKLNKLRVK
LAVLLQKLQLGGPAGDLEQIDAYLEALLKEDHLLFQKAFVNKVTTDTGHHLLLEKKENIS
QN-------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------NRTLTLFWDEFRYDQS--KEIVKDLEYIQYQRRKAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSSTYQEKESLDMWICANNPNHLENSCDQIERLPSIPLGTMNRAA-ASKNEK
DRRLQESVQRYQNRLADLPPQ-----------------------ENSQIQRIRPSG-DNL
TQGSRSSFEFPAGCNSQKR--STEDADSDV--EFVSMTKVMKRPTKKKVKGQQ--QRRTE
TLPGGL-----------------------------RLTGMAQVSSLETERRQSVHLVQES
KVLTEVETSDE-DPDIILVWSKS--STNVSLKQEKQEAP----LITK-EKQELYNDIPVM
KRSSSVLIQ-----KSL--PSVEMEDLSPS--SGHKV-N--SVSGDCQVPSSLM-SSQST
SSAETARKLMSNLREILLYFVADFQLSSEFKCT-AVEDLIAS--PKLEGSPEQINEKLRA
CLNQIQNVYMIQYEKRLKRKI-QAIIYEANRRGILNEVFQGQCEQKKKVAEDKLNSLRTK
LVLLLQKLRLDCPVGDLEQTDAYLETLLKEDNLQT--TLNGKA-----------------
---------------------------------------------

--------------------------------------------MGDRYGALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 187)

FGALAELLDNARDSGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFVLFTKKEETMTCMFFSQTF
CEREGL

ENSGT00530000062983_1_Linker_0_1 (187, 595)

NEVFLPFPQQRY---------FLTFIFELSNFFLYSSFTKTF---SAFKILTGQ
TSVFLPGTLLVIYNLKLLLSGEPELDVKTDKEDILMTGAF--EDFPERWSFRAYASVLYF
DPWMRIFIQAKKVKTKHLCYCLYRPSIKHKKDKINSSFEE-------------IISACLS
LIQWYYVLSQP---------------NVLLQDVLQEALEDVEAKHKNLKEKRRRT-----
-NRTLSSYFNNRFQEVYYISCNSTGIHLIFYSIAKFYKIYIC-----IYSLRLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLKVMGQCLVQYCKDTGI-----------------
-------------SNRNLTWFWNEFGYQNN--KDMDKPLDSIQYQRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTNYQEKEFVDLWICANNPNLLENSCHQVEKLPSIPLGTINTVS-SSKNEK
EKQLRESVQRYQNRLAEQQP-PPQFIPMDRITEFTSARLTSAPKENTKTQKIRLLG-DDS
KHETLSSFELLVSRRGQKR--DTEKTDSDV--EYVSETKIRKKYMRKKMKPQQ--QRHPA
ALTENV--KLAERPQLS---------VWRAQ-TTEGPLRNTQASPWEMKRKQSVNPVQKC
KALIEVETISS-DPDIILVLNKS--NTDTSLKQEKKEIP----LINK-EKQELRIDAPAI
KRNSSLPNW-----KS-----VPMEDVKLS--SGHKDRV--FVSDSCKVASSLT-SFQST
SVKETVRKLISNL-----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------

------------------------------------------------------------
------------------------------------------------------------
----------------------------------MRIGKDFILFTKKEETMTCVLFSRSF
CEEEGLSEVVVPMPSWLTRTRESVTDDPQKFSTELSIIYKYSPFQNEAELMDQFDMICGK
-----CGTLLVIYNLKLLLSGEPELDVKTKKEDILMAGDP--EGFPETWSFRAYASVLYF
DPCMRIFIQAKKVQTKHLCYCLYRPRKYLY---ATSSFKGTLKNEVKKAQ-EAMKIAELL
LKEAQIKVNQPDRT-----------ASSSAQNILEKALEDVEAKHKNLKEKQ----RELK
KARTLSLFFGVNIEN-------PRQYGMFLYSNSRLIKMHEKVGPQLKWKSLLGTGVIGI
VNIPLEIMEPSHNKQEFLNTQEYNQLRKVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFRYQNN--KNAEKSLDSIQYQRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTNYQKEEFLDTWICANNPNHLESSCHDAERLPNIPLGTLNMVL-PSRSEK
EKQLRESIQRYQNKLVEQQA-QLQLIPTGRITEFISTCSVSECKENPQTRKIRPPSGDNL
RHASLSSFELSLSQGSQKR--NADGADSDV--EFISETKIIKKSMQKKMKLQE--QRTAA
AFPRNV--KPAEISQV-LDK----------------------------------------
-------------------------NDAVSLKKEKKEAP----LINK-AKQKLYNGTSAT
RRSSSLPNL-----KSL--PSVPMEG--VS--SGREARV--CVSGSGKIASVPTLSSQST
SVKETERKLISNLREILLYFAPKYLMSSEFNCT-PVEELIAS--IELEQCPEQTNKKLKI
CFDQIQNVYMVQYEKNMKRKL-QSITNEADRRGILNEVSLVHCEHKRKLTEDKLNNLRLK
LAALLQKLQLGGPAGDLEQIDAYLEGLLEDDRLLFRDALK--------------------
---------------------------------------------

--------------------------------------------MADKYATLRRAQLHLD
FIHANS

PF02518 // ENSGT00530000062983_1_Domain_0 (67, 125)

TTHSFLFGALAELLDNARDAGAARLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-D

ENSGT00530000062983_1_Linker_0_1 (125, 593)

IIYFGTSKKRSSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEREGLTEVVVPMPSWLTRTRESVAYDPQKFSTELSIIFKYSPFRNEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLSGEPELDVKTDKEDILMAGAF--EDFPERWSFRAYTSVLYF
EPWMRIFIQAKRVKTKHLCYCLYSPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAELV
LKEAQITVNQPDRT-----------SLSSAKDVLQKAFEDVEAKRKILKEKQRYDARELK
KARTLCLFFGVNIEN-------RSQAGMFIYSNNRLIKMHQKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLRVMGQYLVQYCKDTGI-----------------
-------------SNRNLTLFWNEFGYQSD--KDMEKSLDSVQYQRRQAMAI

PF07496 // ENSGT00530000062983_1_Domain_1 (593, 642)

PFIIQCDL
CLKWRVLPPSITYQEKEFFDFWVCANNPNLLENSCHQAERLPSIPLGTMSSMS-PSKTEK
EKQLREAVQRYHSQLADRQPQKPQFIPTSRITEFTTPCQTSASKKNTKTQKVRLWG-DNL
KQESLASFEPSVSHRGW-KR-NTEGTDPDV--EYIAEAKIMTKSPQKKAKPQQ--HRRPA
ALRANV--SRAQESQVFFFSYPQN--IQTFTYSGDSTGQRFCASSLEMNRKQSQNLVQEC
KALTEVETSNDYCPDIILVRYKS--DTEVSLKQEKKEVS----LMKK-EKQEPCSDTPEI
KRNSSLPNQ-----ERF-RHRAPTGDLSPS--SGHDASF--SVSGGCHVGALLTKSSQST
SVKETVRKLASNLREILLYFLPEYQLSSDFGYT-SVEELAVSFEKQLEQCPEQRNKKLRM
FLNQIQNVYMAQYERELKRKM-QSIIYDANRRGVVNEISLGQCEKKRKMTEDKLNNLRVK
LRALLQKLKLGSPAGDLEQIDRYLEALLKEDNPFFRNALN-KVATDAGRRLPLEKN----
---------------------------------------------

---------------------------------------------MDKYALLQRAKLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAVRLDVFSVDNGTLQGGFMLCFLDDGCGMSPDE
AS-DIIYFGTSKKRLSTLKFIGQYGNGLK--SGSMRIGKDCILFTKKEETMTCLFFSQTF
CEKEGLTEVVVPIPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESITDDTQKFSTELSIIYKYSPFKTEAELMQQFDMIYGR
-----CGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEAL--EEFPERRSFRAYTAVLYF
EPRMRIFIQAKRVQTKHLCYSLYKPRKYQY---TTSSFKGKFKTEVKKAE-EAVKMAELL
FKEVQAKVNQPDRI-----------VLSSAKDVIQKALEDVEAKHKDLRQKQ----RALR
KAKTLSLFFGVHTED-------RSQAGMFIYSNNRLIKMYEKVGPQLKMKSLLGAGVIGI
VNIPLEIMEPSHNKQEFLNVQEYNHLLKVMGQYLIQYCKDTGI-----------------
-------------SNRNLTLFWNKFEDQHS--KDTDSSLEALQWRRRQAMAIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 638)

ILQCDL
CLKWRVLPSSSSYQGKGFPDIWICANNPNNLENSCNQVECLPSIPLGTMNRRP-PAKDER
EKQLQESVQRYRDRLVDTQPQKSQLIVTSKIPEFKTSCLSSAHKEKSRLGRIKPPEDDLT
QGSP-SSAELSFNQRSQKR--STEDADSDV--EFVCVTKIPKKSAKKNLKCLQP-S-HSP
AMLENL--K---------------------------LEDTAQVSSREMKRRQSENLVQER
KAFTQVEASSR-DPTVTVVWDKS--STKVSPKQEK-EEV----ALAKTDKQELCDDAPIV
KRNSSALNW-----KSL--TGVQMEDLSPH--SGHKV-S--SVNSDCQLLSSLM-PSRST
SVEETARKLLSKLREILLYFVPEFQLSSEFECT-SVEELITN--PELERCPESINEKLKT
CFKQIQNIYMAQYEKRLKRKM-QSIIYEANRRVTLNEVLLEQCELKRKRTEEKLSDLCAK
LALLLQKLQLGGPVRDFQQIDTYLEDLLKEDHLST--TLN-KRSLESGQVKGAEH-----
---------------------------------------------

--------------------------------------------MDDRYAALRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNENLQGGFMLCFLDNGCGMNPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRDSVTDDPQKFAVELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPAKWSFRAYTSVLYF
NPWMRIFIQAKRVKTKYLCYCLYRPRKYLY---VTSSFKGAFKNEVKKAE-EAVKIAEFT
LKEAQIKVNQCNTT-----------SLSSAKEVLQRALEDVEAKQKDLREKQ----RELK
KARTLSLFYGVNVEN-------RSQAGMFIYSNDRLIKMHEKVGSQLKLKSLLGAGVVGI
VNVPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDVEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IVQCDL
CLKWRVLPSSTDYQEKEFFDIWICANNPNRLENSCHQIERLPSIPLGTMSTIS-PSKNEK
EKQLRESVLKYQSRLAEQQ-PQPQFIPVDEIT-VTSTCLTSANKENTKTQKIRLLG-DDL
KHESLASFELSVSHRGQKR--DIEETDSDV--EYISETKIMKKSMEEKMNSQQ--QRLPV
ALPENV--KLAERSQESQ--SANIISVWRAQPT-EEPLKNAQAAFWEMKKKQSLNFVEEC
KVLIEDDNSES-DSDIILVSDKS--NTDASLKQEKKEIP----LINQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SEHTAGV--SVSGGDKVASSPS-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEHMNKKLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRVK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNLLLQNNLN--------------------
---------------------------------------------

--------------------------------------------MDDRYAVLRRAQLHLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 196)

FGALAELLDNARDAGAARLDVFTVHNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNALK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEEGLSEVVVPMPS

ENSGT00530000062983_1_Linker_0_1 (196, 595)

WLTRTRESVTDDPQKFSMELSIIYKYSPFKTEAELMKQFDVIYGK
-----CGTLLVIYNLNLLLNGEPELDVKTDREDILMAGAL--EDFPERWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLGYCLYRPRKYLY---VTSSFKGAFKNEVQKAE-EAVKIAEFV
LKEAQMKVNQCDRT-----------SLSSAKDVLQRALEDAKAKQKNLKEKQ----RELK
KARTLSLFYGVNIEN-------RSQAGMFIYSNNRLIKMHEKVGPQLKLKSLLGAGVVGI
VNIPLEIMEPSHNKQEFLNVREYNHLLKVMGQYVVQYCKDTGI-----------------
-------------NNRNLTLFWNEFGYQND--INIERPLNSIQFQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSAHYQEKEFFDIWICANNPNLLENSCHHIERLPSIPLGAMSIVS-PSKNEK
EKQLRESVVKYQNRLAEQQ-PQPQFIPVDKISELTSTCLTSATKGNNKTQKIRLLG-DDV
KRESLSSFQLSVSHRGQKI--NIEETDSDV--AHISETKIMKKSMEEKMNCQQ--QRLPV
ALPENV--KLAERSQKIQ--IANITSVWRAQLI-EGPQKNAQATSWKMKRKQSLNLVEEC
QILTEDENSNS-DPDIILVSDKR--NTDVSLKQEKKEIP----LINQ-EKQELCNEVLAV
KSISSLPSW-----KSL--PNLPVEDVNLS--SGHKARV--SVSGGCKVAFTPV-SSQST
SVKEPVRKLMSKLRETLLYFFPEYQLPSVLEEP-A-------LSCELEQCPEQINKKLKM
CFNQIQNTCMAQYEKKLKRKI-QSVIYDSNTREKRNEISLGQCEGKRKISEDELKNLRIK
LALLLQRLQLGGPEGDLEQIDTYLEALLKEDNLLFQNN----------------------
---------------------------------------------

--------------------------------------------MDDRYPALQRAQLRLD
FIHANSTTHSFL

PF13589 // ENSGT00530000062983_1_Domain_0 (73, 199)

FGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE
AS-DIIYFGRSKKRLSTLKFIGQYGNGLK--SGSMRIGKDFILFTKKEETMTCVFFSQTF
CEEESLSEVVVPMPSWLI

ENSGT00530000062983_1_Linker_0_1 (199, 595)

RTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGK
-----CGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGAL--EDFPARWSFRAYTSVLYF
NPWMRIFIQAKRVKTKHLCYCLYRPRKYLY---VTSSFKGAFKDEVKKAE-EAVKIAESI
LKEAQIKVNQCDRT-----------SLSPAKDVLQRALEDVEAKQKNLKEKQ----RELK
TARTLSLFYGVNVEN-------QSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGI
VNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGI-----------------
-------------NNRNLTLFCNEFGYQND--IDVEKPLNSIQYQRRQAMGIPF

PF07496 // ENSGT00530000062983_1_Domain_1 (595, 639)

IIQCDL
CLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHHIERLPSIPLGTMSTIS-PSKNEK
EQQLRESVIKYQNRLAEQQ-PQPQFIPVDEIT-VTSTCLTSAHKENTKTQKIRLLG-DDL
KHESLSSFELSASHRGQKR--NIEETDSDV--EYISETKIMKTSMEEKMNSQQ--QRIPV
ALPENV--KLAERSQRSQ--IANITTVWRAQPT-EGCLKNAQAASWEMKRKQSLNFVEEC
KVLTEDE-NTS-DSDIILVSDKS--NTDVSLKQEKKEIP----LLNQ-EKQELCNDVLAM
KRSSSLPSW-----KSL--LNVPMEDVNLS--SGHIARV--SVSGSCKVASSPA-SSQST
PVKETVRKLKSKLREILLYFFPEYQLPSELEEP-A-------LSCELEQCPEQMNKMLKM
CFNQIQNTYMVQYEKKIKRKL-QSIIYDSNTRGIRNEISLGQYENKRKISEDKLKNLRIK
LALLLQKLQLGGPEGDLEQIDTYLEALLKEDNLLFQNNLN-KVTIDARHRLPLEKN-ETT
SEN------------------------------------------