Query Results 

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MRSGRTVSAIG
LLSLCLVVCMS---LETI---PPSAFDGYP

PF01108 // ENSGT00510000049322_Domain_1 (271, 399)

DELCT-INITIRNSRLILSWELKNKSGPSA
NYTLWYTVMSK----------------------------------------------D--
--ENLTKVKNCSDTTKSSCDVTDKWLEGMESYV-AIVI

ENSGT00510000049322_Linker_1_3 (399, 423)

VRRGDLTVC--RCSDYMVP-AN
A-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

PLEPPEFEIVGFTDHINVTMEFPPVTSKIIRE-----------RMRSTPFVIKEQIGD
SVRKKHEPK-VNNVTGNFTFVLRDLLPKTNYCVSLYFDDD------PAIKSPLKCIVLQP
GQES--GLS-E---FAKVGGITS-CLI---VMVFVSTIIILKRIGYICLKD-NLPNVLNF
RHFL-TWIFPERSPSEAIDRLEIIPTNKKKRLWNY--DYE-----DGSDSDE---EVPTA
SVTGYTMHGLTG-----------KPLQQTSDTSASPEDPLHEEDSGAEESDEAGAGAGAE
PQ--L----PTEAGAG----PSED---------PSGPYERRKSVLE-DSFPR-EDNSSMD
EPGDNIIFNVNLNSVFLRVLHDE-------------------------------DA-SE-
--TLSLAE-DTILLDEGPH--RTE-SDLRIAGGDRTQPP-LPSLPSQDLWTE-DGSSEKS
DTS--DSD-ADVG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLPSHAFSIVR
LLS

PF01108 // ENSGT00510000049322_Domain_1 (244, 405)

LCLVVCVS---LQFT---SSSVFEDYPKESCD-VNLTLRNFRLILSWELKNKSIPLT
HYTFWFTIMSK----------------------------------------------P--
--EDPKALENCTNITEPSCDVTEEWTGPSEIYV-PLIVIYRGNS

ENSGT00510000049322_Linker_1_3 (405, 422)

TVS--LCEGSVVA-TD
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 537)

-RVEPPEFEVVGFTDHINVTMKFPPVTPKIFGESI-------WEMLGYKSLVIREQAGQ
SIK-LHKPT-MKSITGNFTYVLRDLLPKTNYCVSVYFEAETL---ETSIKSPFKCTALQP
DQES--GSS-E---YDKVGIVTG-CVI---AVLFFSIVVMLKRIGYICLKH-NFPNALNF
HNFL-SWIFPEVPPSEGVDKLEIIPSSKKKKVWNY--DYG-----DGSDSDE---DVPKA
SATGYTTHGLMG-----------RLLSQASDPANHPLESQLEEDSAAEESDAT--EPGTE
PE--L----PTEAVVGLGLRPSED---------PSGPYERRESVLQ-DSFPG-DDSSSVN
GTGDKVIFNVNLNSVFLRVLHDDS-----------------------------EGG-SE-
--VSSLAE-DPVHLDEAPH--RTE-SGLPMAGEDRTQSP-HPSVSSQGLWTE-DGSSEKT
DTS--DSD-ADTG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MKSSSFWVSRT---PGLLGKACLLEVRDSRSQETGWTVTKIQ
PWVR--DFNFS---FLFF---L-PLPLDSSDES

PF01108 // ENSGT00510000049322_Domain_1 (274, 404)

CT-LKMRFRNSQSILSWELKNHLVVPT
HYTLWYTIMSK----------------------------------------------Q--
--ENMKMVETCANITRSFCDLTDVWINLTETYI-PRVVAFREN

ENSGT00510000049322_Linker_1_3 (404, 423)

TALV--TCMGSFFMATD
TM

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SLDPPDFEVAGFTDHINVNVNFQSVVSKTLNEEE---------LQFYLVQVIEKPSGG
IAKKHKPRI-KGNITENFNYVIDKLIPNTNYCVSVYFEPKDQ---NKINRSPLKCTFIQ-
-RES--ESS-E---STKLGGIITLFVI---AAVFISTIVTLKRIGYICLRN-DFPKVLTF
SKLS-AWVFPELPPLENVSTVEIIHNHRKKKEWNY--NYD-----DESDSDS-EA-APQK
NAGGYTMHRLR------------PLCPASTSS-ATLE----------DYCSDPDTEDPDL
PEPEA--AAEAPEAPGPSAWQSEY---------QSGGYERRVSLQQ-DPYFP-EDSSPPE
GSQDRIVFNVDLKSVCVRVLDDDDDDSDDDDDNDNDDDDEDDNGDEDEDEDDDSEVTPM-
--LSSQPE-GTAG-LEDAT--ETES-NLLEVSGKGTQQPFFPSPSMARPGPK-DASSDKS
DTSE--SD-ADIG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MPWARSALAIR
LASLYLMVHVG---PSLG---APQASLASSDESCI-FSLTLRNFRPILSWELKNRSIVPT
HYTLRYTIMSK----------------------------------------------A--
--EALQLVPECANITRPSCDLTHQWHNLNEMYL-PWVIGSRGSATLV--NCAGMVSPFVE
-MILEP

PF09294 // ENSGT00510000049322_Domain_3 (427, 549)

PEFEIVGFVDHINVILKFPPSLPKLPPGKG---------LWLHLSLSIEEESEG
IVRQHLLKI-DERTTGNFTYVIDKLIPNTNYCVSVYLKLENL---SKL-RSPWKCARLPP
RPEP--VSS-E---SASIGGLTVLFLM---A-VLGGAFTVLRRIGYICLRS-KFPKVLNF
DDVA-IWAFPKLPPLEAVAVAEVIHVHRKRKVWDY--NYD-----DESDGDE-EA-APQA
SGGGYTMHGLPV-----------RPLCPGSPSSATLG-----------GSEEA-------
---------ESQMAPGPEAWPTERTTSKEEEEVVVVEEEEEGTWPA-DPFPR-EDSGPTK
SPGDRIFFNVDLNSVLVRVDGDD------------------------------SGAHPV-
--F-CLPE-ETVD-ADDPE--DS------------------------AAGPE-DAPFDGN
DPSR--SD-VGIG--DGYMMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MMLSSHRAWAIR
L

PF01108 // ENSGT00510000049322_Domain_1 (242, 403)

LTLCLVVYVS---LALD---SPRISPDDPGEHCN-FKVTFRKYRLILLWELKNHSIVPT
HYAFEYTIMSK----------------------------------------------P--
--EGMKIVKNCTNITSSFCDLTDVWQDMHEMYI-PLVKAYRG

ENSGT00510000049322_Linker_1_3 (403, 424)

TALLV--QCAGSIMT-TN
L-A

PF09294 // ENSGT00510000049322_Domain_3 (424, 536)

IEPPDFEVVGSADHISVTVSFPSLAPMVYKEDL----------RDHASLVIEEHLEN
NVKRHEPPI-NGSFIGNFSYVLNDLIPNTNYCVSVYFESIRF---TPTVKAPLKCILYQP
GQES--GTS-E---SLKIALLTI-FFI---VAVAISIVYALRQSGYVSLHT-NFPKALIF
KNFV-PWTVPDLPLLEDVNTVEVCYINRKKKVWDY--NYD-----DESDSENE-A-SPRT
SEGGYTMHGLTS-----------RLLSQIPTSSATSQASHPE-DSADEESEEPEEETQPQ
P--QP----WLPAALGPSPGQREC---------TSESCERTGGLPQ-DLSFGDNDSNSTE
GSGGKITFNVNLSSVFLRVLHDDP--------------------------EDSEEA-SL-
--VLTPPE-ETVNLEESSQ--ETE-SSLLVAGGEKLQVL-FPSLPPKCLWTG-DDLSDES
DTGS--SD--VDDVRDGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------EKPCT-LKITLRNFQSIFSWELKNHSIVPT
HYTLWYTIMSK----------------------------------------------P--
--EGMKMVEGCTNITRPFCDLTDLWNNMHETYI-PRVVAFKGNTELV--SCVDSIFLPLN
-MSFDP

PF09294 // ENSGT00510000049322_Domain_3 (427, 549)

PDFEIVDSMGHINVIVKFPYNAP-KISVDR---------LRRHLSLVIEQRSEE
IVKKHKPKI-TGNVTGDFVYVLDKLIPNTNYCVSVYFEPKNL---RAVIRSPLKCTLL-P
GLEP--ESS-E---SAIIGGIVTVFLI---ATVFISSIVTLKRIGYIYLRY-NLPDALVF
FLHFVSWIFPEPPPLEAVDTVDVIYINRKKKVRDY--NSD-----DETDSED-ET-APRV
SAGGYTRHGLIT-----------KLLTQASTSLSTSK---------ESQLIDLDVGEDYL
S--EA--EAEPPLVPEPSSGQSEC---------ASGPYDRRESELQ-DPFSE-EDNSSTE
GSGDRIIFNVNLNSVFVRALDND----------------------------DDGDVSPM-
-----LPE-ETVD-LENPD--EME-SSFLIPREEGMPPP-FPSTSEEHLESE-DAPSEKS
DSSE--SD-VDIG--DGYVMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MPSKGTGSAVG
LLSLY

PF01108 // ENSGT00510000049322_Domain_1 (246, 400)

LVVCVS---LQSN---SSFAFEEYPDEPCT-INLILRHFRLILSWELQSQSSPPT
NYTLWYTIMSK----------------------------------------------A--
--EDLKKVENCIDITEPLCDVTDEWLEGRETYV-PIIVV

ENSGT00510000049322_Linker_1_3 (400, 424)

HRGDSTVC--RCSDYIWP-TN
V-L

PF09294 // ENSGT00510000049322_Domain_3 (424, 537)

LEPPEFKLIGFKDHINVMMEFPPATYKLFGESL-------WKRLESTSFVIEEQTED
SIR-VHKPQ-MNNVTGNFTYVLRDLLPKTNYCVSVYFDDT------PVIKSPLKCTVLQP
DQES--GLS-E---SAKVGIFIG-CLI---VMAFVSTVIMLKQIGYICLKD-KFPNALNF
HHFL-TWIFPEWPPSEAIDWLEVIPKNTKKRLWNY--DYG-----DGSDSDE---EVPKT
SVTGYTMHGLMG-----------KPLPQTSDDSPNPEEPPHEEDSGAEESDEARAGAGAE
PQ--L----PTEVKAG----PTED---------PSGPYERRKSVLKDDSFPG-EDNSSMD
APGDRVIFNVNLNSVFLRALHDE-------------------------------DA-SE-
--TISLTE-DTVLLDEGPH--RTE-SDLQIAGRDRTQLP-DPSFSSQGLWTE-DESSEKT
DTS--DSD-TDAG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
SLNLVLMEYNCGFQISMP---FFFFSLDYTDESCT

PF01108 // ENSGT00510000049322_Domain_1 (276, 405)

-FKISLRNFRSILSWELKNHSIVPT
HYTLLYTIMSK----------------------------------------------P--
--EDLKVVKNCANTTRSFCDLTDEWRSTHEAYV-TILEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLAID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVMVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KGNLSGNFTYIIDKLIPNTNYCVSVYLEHSDE---QAVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIITVFLI---ALVLTSTIVTLKWIGYICLRN-SLPKVLNF
HNFF-AWPFPNLPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQLI-DPES----EE---EPDL
PEVDV----ELPTMPKDSPQQLEL---------LSGPCERRKSPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--LSSHLE-EMVD-PEDPD--NVQ-SNHLLASGEGTQPT-FPSPSSEGLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MRSRCTVSAVG
LLSLCLVVSAS---LETI---TP

PF01108 // ENSGT00510000049322_Domain_1 (264, 396)

SAFDGYPDEPCT-INITIRNSRLILSWELENKSGPPA
NYTLWYTVMSK----------------------------------------------D--
--ENLTKVKNCSDTTKSSCDVTDKWLEGMESYVVA

ENSGT00510000049322_Linker_1_3 (396, 423)

IVIVHRGDLTVC--RCSDYIVP-AN
A-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

PLEPPEFEIVGFTDHINVTMEFPPVTSKIIQE-----------KMKTTPFVIKEQIGD
SVRKKHEPK-VNNVTGNFTFVLRDLLPKTNYCVSLYFDDD------PAIKSPLKCIVLQP
GQES--GLS-E---SAIVGITTS-CLV---VMVFVSTIVMLKRIGYICLKD-NLPNVLNF
RHFL-TWIIPERSPSEAIDRLEIIPTNKKKRLWNY--DYE-----DGSDSDE---EVPTA
SVTGYTMHGLTG-----------KPLQQTSDTSASPEDPLHEEDSGAEESDEAGAGAGAE
PE--L----PTEAGAG----PSED---------PTGPYERRKSVLE-DSFPR-EDNSSMD
EPGDNIIFNVNLNSVFLRVLHDE-------------------------------DA-SE-
--TLSLEE-DTILLDEGPQ--RTE-SDLRIAGGDRTQPP-LPSLPSQDLWTE-DGSSEKS
DTS--DSD-ADVG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MRSRCAISAVG
FLCLCLVV

PF01108 // ENSGT00510000049322_Domain_1 (249, 401)

CES---LETI---SPSAFDGYPDEPCT-INMTIRNFRLILSWELENKSSPPA
NFTLWYTVMSK----------------------------------------------N--
--EDLMKVKNCSDTTKSSCDVTAEWLEGMESYV-AIVLVH

ENSGT00510000049322_Linker_1_3 (401, 423)

RGDLTVC--RCSDYIVP-AN
A-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

PLKPPEFEIIGFTDHINVTMEFPPVTSKIIRE-----------KMRSTPFVIKEQIGD
SIRKQHKPK-VNNVTGNFTFVLKDLLPKTNYCVSVYFDDD------PAIKSPLKCIVLQP
DQES--GLS-E---SAKVGIITS-GLI---VMFFVSTIIMLKRIGYICLKD-NLPNVLNF
HHFL-TWIFPERSPSEAIDRLEIIPTNKKKRLWNY--DYE-----DGSDSDE---EVPTA
SVTGYTMHGLTG-----------KPLPQSSDTSASPEDPLHEEDSGAEESDEAGVGAGAE
PQ--L----LTEAGVG----PSED---------PSGPSERRKSVLK-DSFPS-EDNSSMD
EPGDNTIFNVNLNSVFLRVLHDK-------------------------------DA-SE-
--TLSLAE-DAILLDEGPH--RTE-SDLRIAGEDRTQPS-LPSLPSQDLWTE-DGSSEKS
DTS--DSD-ADVG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSWNASAIR
S

PF01108 // ENSGT00510000049322_Domain_1 (242, 405)

LILFLMVCIS---LAFH---ISRDLPDYANESCT-VKISLRNFRSILSWELKNHSIVPT
HYTLVYTIMSK----------------------------------------------P--
--EDMKTVKNCANTTRSFCDLTDEWKSTHELYL-INLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLL--TCTHIFWLAMD
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVDFTSHINVTVKFPSVV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KRNMTGNFTYVIDKLIPNTNYCVSVYFESKDQ---EAVIKSPLKCTLRQP
CQES--ESA-E---SAKVGGIITLFLI---VLVLISTLVTLKRIGYICLKN-SLPKALNF
RNFF-TWPFPELPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSETE-A-APRT
SGGGYTMHGLTL-----------RALGQPSA---TSAESQFV-DPDS----EE---EPKL
PEVDA----EPPTMPTCSPQQLEH---------LSGLCERRESPLQ-DPFPE-EDYSSTK
GPGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHPE-EMVD-PEDPD--NME-SSHVLASGEGTQPA-FPSPSSEGLCPE-DASSDQS
DTSE--SD-ADLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFI

PF01108 // ENSGT00510000049322_Domain_1 (239, 405)

VR
PLNLFLMVCIS---LVFG---ISHDLPDYTGESCT-FKISLRNFRSILSWELKNHSIVAT
HYTLLYTIMSK----------------------------------------------P--
--EDLKMVKNCANTTRSFCDLTDEWRSTHEAYV-TILKGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHSFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 536)

SFEPPEFEIVGFTNHINVIVKFPSIV----KEEL----------QFDLSLVIEEQSEG
IVKKHKPAI-KGNMSGNFTYIIDKLIPNTNYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---ALVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRM
SGGGYTMHGLTV-----------RPLGQTSA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTMPKCSPQRLEL---------LSAPCERRESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPVM-
--VSSHPE-EMVD-PEDPD--NVQ-SRHLLASGEGTQPT-FPSPSSEGLQSE-DAPSDQS
ETSE--SD-VDFG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
PLN

PF01108 // ENSGT00510000049322_Domain_1 (244, 405)

LFLMVCIN---LVFG---ISHDLPDDTSASCT-FKISLRNFRSILSWELKNHSIVAT
HYTLLYTIMSK----------------------------------------------P--
--EDLKMVKNCANTTRSFCDLTDEWRSTHEAYV-TIVKGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----KEES----------QFDLSLVIEEQSEG
IVKKHKPAI-KGNMSGNFTYIIDKLIPNANYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLM---ALALISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-AWPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
NGGGYTMHGLTI-----------RPLGQASA---TSTESQFM-DPDS----EE---EPDL
PEVDV----ELPTTPKRSPQQLEL---------LSAPCERRESPLQ-DPFPE-DDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHLE-EMVD-PEDPD--NVQ-SSHLLASGEGTQPT-LPSPSSEGLQSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MVWNQNASLVR
PQNLYLVVC

PF01108 // ENSGT00510000049322_Domain_1 (250, 405)

IS---FVFG---VSSAFPDLSDKFCT-FKVTFRNFRLILSWELKNHSVVPD
RYTLRYTVISR----------------------------------------------P--
--DQVKIVEHCSNTTASSCDLTDVWEVLPETYS-IRVDGFRGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLV--QCSSYLFLVTH
-M

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SLEPPEFDIVGFTDHINVLVKFPPVIPKILGGGV---------LKFYLSLIIEEQSGN
IVKKHNPEL-NENITGNFTYVIDKLLPNTNYCVSVYFKPRNL---GAVHRSPVKCILLQP
GQET--ESS-E---SAKIGGIITMFVI---AAVIVITIIILKRVGYICLRN-HFPKVLNF
YNFS-TWVFPEMPPLETVAFVEVIHVNRKKKVWDY--NYD-----DESDSNDDTA-TPQT
NAGGYTMHGLVG-----------RLLGPASASSATPE-----------DCMEPDAEEPDP
SEPDTDIDTEPLVPSGPSPGQSEG---------TSGAYECRGKQLQ-DPITE-EDSWSTG
GSGDKITFNVNLSSVFMRVLDDD------------------------------LEVPPG-
--LPSFPE-ETYN-LQESH--RLE-TSSLAANGEGTQPL-FPTPSAECQWPE-DVLSDES
DSSE--SD-VDIG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MMALLMG
PLNFYNLVYIS---VIA-SASYSSFEKN--TSSSLQPHINAKDFEYVLTWKTGNNTRMPT
CFNVIYYSSSLETKSNSEKKDEGQDASSSKSRFQQSEDPNHPVLQPGEPSVCPSMPERSD
WFK

PF01108 // ENSGT00510000049322_Domain_2 (364, 404)

NHRIVPECSNITRPFCNLTKEFTDLWTTYL-ILVEQVTKN

ENSGT00510000049322_Linker_2_3 (404, 424)

GVTR---SLIEFSPYSN
S-C

PF09294 // ENSGT00510000049322_Domain_3 (424, 538)

LGQPQFNVSSCPNCVNVSVKLSSPLLLKV-----------Y---RDISYTIKVSTAG
F--PDKRDD-NTTKQESFSVVMGNLLPNRNYCITVDVFTNLN---TQCSPSSPKCIITGS
KNKS--IKQSDHIIIPVS-LGIFVSLI---VIVILLV---LYKIGLICLRT-DWPNILDF
IP-K-FAYSTFDSVPEEVHSVKVTE-KTKKKVWRCDDNGDGDDYSDDSGSDV-------E
NNHLYTVRKQLKNGSTV------DIVEQLSLDSSSPEN-------------------DVS
E-PGV------AEADILQ---NE----------ISKDESITTRQPL-CDSSK-GNATNEP
ELELSSCLNVNLNSVKLGISINTQ------------------------------DVPAS-
--LDPPDHEDSANVKEPC--ITSD--STHFTDTSNVQTPNVHSLF--STWQNPGAS-GES
ESSD--SE-TDYV--GDYIKRESNQENITT--

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLWSQNASPLR
SRNLCLVV

PF01108 // ENSGT00510000049322_Domain_1 (249, 406)

CIS---LLSG---VLSSLPDLSDKSCT-FKVTLHNFRVILSWELKNRSIVPD
RYTLQYTVISR----------------------------------------------P--
--DGVKIVEHCSNITASFCDLTDVWEVLPETYA-VMVDGFRGNTT

ENSGT00510000049322_Linker_1_3 (406, 423)

LV--TCFTDFFLAAE
-I

PF09294 // ENSGT00510000049322_Domain_3 (423, 536)

SLEPPEFDIVNFTDHINVNVNFPPVLPKILE-EL---------LQFHLSLIIEEQSGE
IVKKHNPAL-DEHVIGNFTYVIDKLLPNTNYCVSVYFMPRNL---EAIRRSPIKCTLLQP
ARDT--GLS-E---SARIGGIITMFLI---AAVFISTIIILKRVGYICLRN-NFPKVLNF
LNLS-AWVVPEMPPWEAVAFVEVIHINRKKKEWNY--NYD-----DESDSNDEAT-APLT
STGGYTKHGLLT-----------GLPGPTSASSPTGQ-----------DCLELDTEEPNL
SEPKGEPP----MAPE--------------------PSLGRGKLLQ-DCFFE--DGSSTE
EAGDKIVFNVNLSSVFVSTLDDDVST-----------------------LDDDSDVPPV-
--LPSFPE-E------DSH--TPE-PSFLATSREGTQQP-FPTPSAECPWPE-DVLSDKR
DSSE--PN-VDIG--DGYIMSVRQVTNRKHLH

------------------------------------------------------------
------------------------------------------------------------
MGGGERQCVTWAGWNGLIWSSEPFKDSQVKKPFCPDSVY--TVQSSCFLCLPALT-----
TCCLLINLLVYFPCPVDFLFS----RLQG----SLEGLSARGVGSRSQEMTEQWPGYNLG
---------FQ---ISMP---FFLFSLDYANESCT

PF01108 // ENSGT00510000049322_Domain_1 (276, 405)

-VKISLRNFRSILSWELKNHSIVPT
HYTLVYTIMSK----------------------------------------------P--
--EDMKMVKNCANTTRSFCDLTDEWKSAHELYL-INLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLL--TCTHIFWLAMD
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVDFTSHINVTVKFPSVV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KRNMTGNFTYVIDKLIPNTNYCVSVYFESNDQ---EAVIKSPLKCTLHQP
CQESDSESA-E---SAKVGGIITLFLI---VLVLISTLVTLKRIGYICLRN-SLPKALNF
RNFF-TWPFPELPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSETE-A-APRT
SGGGYTMHGLSL-----------RALGQASA---TSAESQFV-DPDS----EE---EPEL
PEVDA----EPPTMPTCSPQQLER---------LSGLCERTESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDVEEAPLM-
--ISSHLE-EMVD-PEDPD--NME-SSHVLASGEGTQPA-FPSPSSEGLCPE-DAPSDQS
DTSE--SD-ADLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MQLSRCESRERTYRLTRMLPSHAFSIVR
LLS

PF01108 // ENSGT00510000049322_Domain_1 (244, 405)

LCLVVCVS---LQFT---SSSVFEDYPKESCD-VNLTLRNFRLILSWELKNKSIPLT
HYTFWFTIMSK----------------------------------------------P--
--EDPKALENCTNITEPSCDVTEEWTGPSEIYV-PLIVIYRGNS

ENSGT00510000049322_Linker_1_3 (405, 422)

TVS--LCEGSVVA-TD
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 537)

-RVEPPEFEVVGFTDHINVTMKFPPVTPKIFGESI-------WEMLGYKSLVIREQAGQ
SIK-LHKPT-MKSITGNFTYVLRDLLPKTNYCVSVYFEAETL---ETSIKSPFKCTALQP
DQES--GSS-E---YDKVGIVTG-CVI---AVLFFSIVVMLKRIGYICLKH-NFPNALNF
HNFL-SWIFPEVPPSEGVDKLEIIPSSKKKKVWNY--DYG-----DGSDSDE---DVPKA
SATGYTTHGLMG-----------RLLSQASDPANHPLESQLEEDSAAEESDAT--EPGTE
PE--L----PTEAVVGLGLRPSED---------PSGPYERRESVLQ-DSFPG-DDSSSVN
GTGDKVIFNVNLNSVFLRVLHDDS-----------------------------EGG-SE-
--VSSLAE-DPVHLDEAPH--RTE-SGLPMAGEDRTQSP-HPSVSSQGLWTE-DGSSEKT
DTS--DSD-ADTG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR

PF01108 // ENSGT00510000049322_Domain_1 (241, 405)

PLNLFLMVCIS---LVFG---ISHDLPDYTSESCT-FKISLRNFRSILSWELKNHSIVAT
HYKLLYTIMSK----------------------------------------------P--
--EDLKIVKNCANTTRSFCDLTDEWRSTHEAYV-TSLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--NCSHNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPTI-KGNMSGNFTYIIDKLIPNTNYCVSVYFDHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---ALVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-ALRT
SGGGYTMHGLTV-----------RPLGQTSA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTTPKCSPQRLEL---------LSAPCERRASPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--VSSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQPT-FPSPSSEGLQSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFI

PF01108 // ENSGT00510000049322_Domain_1 (239, 405)

FR
SLNLVLMVYIS---LVFG---ISYDSPDYTDESCT-FKISLRNFRSILSWELKNHSIVPT
HYTLLYTIMSK----------------------------------------------P--
--EDLKVVKNCANTTRSFCDLTDEWRSTHEAYV-TVLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLAID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVMVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDE---QAVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIITVFLI---ALVLTSTIVTLKWIGYICLRN-SLPKVLNF
HNFL-AWPFPNLPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQLI-DPES----EE---EPDL
PEVDV----ELPTMPKDSPQQLEL---------LSGPCERRKSPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLE-APLM-
--LSSHLE-EMVD-PEDPD--NVQ-SNHLLASGEGTQPT-FPSPSSEGLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIIR
SLYLFLMG-----------------KCYYTDESCT

PF01108 // ENSGT00510000049322_Domain_1 (276, 405)

-FKISLRNFRSILSWELKNHSIVPT
HYTLLYTIMSK----------------------------------------------P--
--EDLKMVMNCANTTRSFCDLTDEWRSTHEAYV-TILEGFSGNTTLF--SCSHNFWLAID
S-EFTVSPLFLLIF---------------------------------------------C
LCLQH

PF09294 // ENSGT00510000049322_Domain_3 (486, 537)

KPEI-KGNMSGNFTYILDKLIPNTNYCVSVYFEHGDE---QPVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIITVFLI---ALVLTSTIVTLKWIGCICLRN-SLPKVLNF
HNFL-AWPFPNLPPLEVMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQFI-DPES----EE---EPDL
PEVDV----ELPTTPKGRPQHLEL---------LSGPCERRESPLQ-DPFPE-EDYSSNE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQQT-FPSPSSEGLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MFSNYNVSAIT
L

PF01108 // ENSGT00510000049322_Domain_1 (242, 403)

LNLYLMVYVS---VLFG---TSPTFSEYSDESCT-MNLTIQNFQLILSWEVKNRSIQPT
HYTLWYTIMSK----------------------------------------------P--
--EDPKIVGNCTNITKPSCDLTDVWEIMDDHYI-PIVELYKG

ENSGT00510000049322_Linker_1_3 (403, 424)

NSMVG--RCMNSFWA-SD
F-Y

PF09294 // ENSGT00510000049322_Domain_3 (424, 537)

IEPPRFEIVGFLDHINVTLEFPSVTPKIYGKEI----------QEYASLVIEKQWDK
IVKLNDLKL-NRDFSGNFTYILDNLIPNTNYCVSVYFEPLDV---EKIIKSPIKCIFLQP
DQES--GLS-I---SAKIGIIIT-GWI---VLFFISSILMLRRTGYICLKN-NFPKVLNF
HNFL-ASMFAEPPPSEAVDMLEIIHTNKKKKLWNY--SYG-----DESDSEEEEEEVPKA
SATGYTTHGLMG-----------KHLSQAPDPSASSQESQCE-DSAVEESDEPGAELE--
----P----PREARPD--PWQPES---------SRSPRERRERVLQ-DSYPR-HNSSSTD
EPGDKVIFNVNLNSVFLRVLDDE-------------------------------ET-SE-
--VLPLAE-DTIDLEEDPH--RIE-SSLLMASGERTQPP-HHSSSSQCLWTE-EESSDKT
DSSGSDTD-ADVG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
SLNLVLMEYNCGFQISMP---FFFFSLDYTDESCT

PF01108 // ENSGT00510000049322_Domain_1 (276, 405)

-FKISLRNFRSILSWELKNHSIVPT
HYTLLYTIMSK----------------------------------------------P--
--EDLKVVKNCANTTRSFCDLTDEWRSTHEAYV-TILEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLAID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVMVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KGNLSGNFTYIIDKLIPNTNYCVSVYLEHSDE---QAVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIITVFLI---ALVLTSTIVTLKWIGYICLRN-SLPKVLNF
HNFL-AWPFPNLPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-AHRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQLI-DPES----EE---EPDL
PEVDV----ELPTMPKDSPQQLEL---------LSGPCERRKSPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--LSSHLE-EMVD-PEDPD--NVQ-SNHLLASGEGTQPT-FPSPSSEGLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLWSHCAWAIR
LLI

PF01108 // ENSGT00510000049322_Domain_1 (244, 402)

WCLVVCVS---LALD---A---SPDIPGEHCN-FKMTFGKYRSILSWELKNQSFEPT
HYALQYTIMSK----------------------------------------------A--
--EGLKIVEECTNVTKSSCDLTDVWQDVHETYV-PLVKVFR

ENSGT00510000049322_Linker_1_3 (402, 423)

GRTLMV--QCTDSITA-TN
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SIEPPDFEIVGFANHINVAVQFPLMAPKIFGEEL----------HKQASLIIDEHSEN
IDKRHEPNI-NGSFSGNFSYVLNNLIPNTNYCVSVYFESKSS---TTVIKPPLKCILLQA
GQVS--GTS-E---SVKIVALAI-IFI----SVAIGVILTLRQIGCVCLHT-NFPKVLIF
RNFI-TQRVPEVPLLEEVNTVEVISINRKKKVQDS--NDDD--DDDESDSEDE-A-PLRI
SGGGYTIHGLTG-----------RLLSQMPTSSATSQASHLE-DSANESSEEPEEETQPQ
PQPRP----RPPAALGPSPGQRER---------TSEPCERTKGPLQ-DPCPGDSDSNSTG
GSGDKITFNVNLNSVFLRVLHDDP--------------------------EDSEEA-ML-
--VLPPPG-DTVDLEEDPQ--ETQ-SSLLVAGGEKLQVL-FPSLPPECLWTG-DDLSDKS
DTSG--SD-ADDDVRDGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MVLSQNVSAVG
PLNLYPMVHIS---LMFG---ISYVLPDFSDESCT-LKMTLRNLQSVLSWELKNHSIVPT
HYTLWYTIMSK----------------------------------------------H--
--EDMKIVGDCTNITRSFCDLTDVWVNMTEMYI-PKVVGFRGNAELV--SCMGSFFLAMD
-MPLDP

PF09294 // ENSGT00510000049322_Domain_3 (427, 549)

PEFEIVGFTDHISVNVKFQSVAPKILNEEE---------LQFYLA-LIEEQSGG
TVKKHKPQI-NGNVTENFIYIIDKLIPKTNYCVSVYFEPKHP---RKINRSPLKCTLFQP
GWES--ESS-E---SATIGGIITLFLV---AAVVISTVMMLKRIGYICVRN-NFPKVLNF
NKLS-VWVFPELPPLEKVATVELIHINRKKKVWNY--NYD-----DESDSDD-EA-APRI
SAGGYTTHGLTG-----------RPLCSA-----------------TGGLQDPATEERDL
PEPEA--DAEALTAPGPSPWQSEC---------TSRGYQGRGNLLQ-DPFSE-EDSSPTE
GSGDRIVFNVDLNSVCVRALEDN----------------------------DDSEVTPM-
--LASGPE-ETAV-LEDPD--ETESNLLLVASGEGTQLP-FPGPSAEYPWPE-DSPSDES
DTSE--SD-VDMG--DGYVMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNVSAI

PF01108 // ENSGT00510000049322_Domain_1 (240, 405)

G
PLNLYPMVHIS---LVFG---ISYVAPVLSDEHCT-LKMRFRNFQSVLSWELKNHSIVPT
HYTLWYTIMSK----------------------------------------------R--
--EDMKVVKDCINVTRSFCDLTDVWVNTTDMYI-PQVVGFRENA

ENSGT00510000049322_Linker_1_3 (405, 424)

KLV--ICMGSFFLVPD
-KP

PF09294 // ENSGT00510000049322_Domain_3 (424, 536)

LDPPEFEIVGFTNHISVNVKFQFDSPGILS-EE---------LQFYLA-FIEEHAGN
SVKRHQPQI-TGNITKNFNYVIDKLIPNTNYCISVYFEPKDP---RKINRSPLKCTLFRP
RRES--ESS-E---SATIGGIITLFLI---TAVFISTVMILKRIGYICLRN-DFPKVLNF
YKLS-VWVFAELPPLEKVATVEVIHVNRKKKVWNY--NYD-----DENDIEN-EA-APHL
ISGGYTKHGLTG-----------KLCPTSTTS-PSLED------CSLEDCSEPSAEEPYL
PEPKG--DAETPMAPGPGPWQSEG---------TSGGYQTRGTLWQ-DPTSE-EDSDSTE
GSEGRIVFNVNLNSVCVRALEDD----------------------------KDSEVTLM-
--SPSCPE-ETVE-L-EDL--NETESSVLVASEEGTQLP-FTNPSTECPRPQ-DAPSDKS
DTSE--SD-VDMG--DGYIVRQVNLKKFN---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLWSQNAFRIS
PLKLCLLACAS---FLFG---ISCALPDASKKPCH-FKLTLQNFRSILSWTFKNHSVEPT
HYTLQSTIMXX----------------------------------------------X--
--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX--XXXXXXXXXXX
XXXXXXXXXXXXX

PF09294 // ENSGT00510000049322_Domain_3 (434, 549)

XXXXXXXX-XXXX------XXXX-------XX-XXXXXXXXXXXXXX
XXXXHKLGL-NRNISGNFTYVIDKLIPNTNYCVSVYFKHRD-----PDVKPVIRCAFLPP
GNQS--ESL-E---SDKAGGIIGLF----M-LVAVIVTMVLRRTGYICLKT-DYPHVLYF
KHLP-TCTFLELPPLEAMDAVEVILVPRKKKKDYN--SEEE------SDNDQE--NIPRS
NGGGYTMHGLVG-----------RPLDPASMSSATGGPHPMV------------LEEVDE
SEPEA--ELEPLVAPLECPQWGL----------SSGAYEGRREPPQ-YSLPG-E-DSAPE
EPEDRRTFNVDLKSVCVRILDEDP-----------------------------DDV-PP-
--VLTLPE-EMVD-LEEPE--DLC--QW-LSG--GPAPP-SAGLSEVDQWAE-GVPSEET
DSCE--SE-VDVG--DGYLAR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNASAIR
SLNLIL

PF01108 // ENSGT00510000049322_Domain_1 (247, 404)

MVFIS---LVFG---VLRDLPDSSNEPCV-LKITLQNFRSILSWEFKNHSVVPT
HYTSLYTVMSR----------------------------------------------K--
--EALKTVEGCVNTTRSFCDLTRVWKNIHEIYI-ITVEGFRGN

ENSGT00510000049322_Linker_1_3 (404, 425)

TLLV--HCTKTFLPAMD
I-SS

PF09294 // ENSGT00510000049322_Domain_3 (425, 537)

EPPEFEIVGFTDRINVTVKFPSNI----EEGL----------QFDLPLVIEEESEG
IVKKHVPKM-KGNMSGNFTYVIDRLIPNTNHCVSVYFESADQ---ATVVKSRLKCTFLQP
VQES--EPS-E---SGKIGGIITMFLI---AVILTSTIIVLKRIGYICLRK-KFPKVLNF
HNFS-AWIFPELPPWEAMDMVEVIYINRKKKVWDY--NYD-----E-SDSDNE-A-APRA
SAGGYTMHGLTV-----------RPLSQASAASAASKESQFI-DPDS----SE---EPDL
PEAAA----EAPTMPGHSPWQLEH---------MSGPYERRKSPLQ-DPFLE-EDSSSTE
QSGDRIIFNVDLNSVLMRVHDN---DK--------------------DDSDNSEEDPLM-
--LSVLPE-ETVG-PEDAD--ERE-SSLLLASGEGTQTA-YLSPSSEHLWPE-DAPSDKS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MVFGLQAPLTR
PLHLYPWVCIG---LMLG---TSHVLPDFLDKPCT-MKLKMQDFQFILSWELKNRSVVPT
HYTLWYTVMSK----------------------------------------------P--
--VAMKMVEDCTNITRSYCDVTDWWKNLHDTYF-PKVVGFTGNTVPI--SCMDSFSLPVN
-ITLEP

PF09294 // ENSGT00510000049322_Domain_3 (427, 549)

PDFDIFGSANHINVVVQFPPPGPRRVDVGK---------LRHYLSLVVEQRSGE
MVKKHKPKI-NQN-TGDFIYVMDKLIPSTNYCVSVYFEPKSL---APVTRSPLKCTVL-P
DQEP--EPS-E---SAKIGGIITVFLI---AAVFISSLLVLKRVGYICLTK-YLPDALKF
YNKQA-SMFLEVPPLEAVDPVEVIHVERKKKVWDY--SYG-----DESDSED-EA-TPRA
SAGGYTRHGLIP-----------LPPVQAPAPWSTSE---------DSLFREPEVEDPDQ
P--EA--EVEPLLIPAPSTGQSEH---------ASAPSKGRDSGCQ-DPFSE-EDSSSIE
DSGGGAIFHVNLNSVCVRALDDD----------------------------DDGDVSLV-
-----LPD-ETVD-LEDPE--DVE-SSFLIPGEAGMLPP-FPSPSEECPGSE-DALSGKS
DTSE--SD-TDTR--DGYIMRQ----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
SLNLVLMEYNCGFQISMP---FFFFSLDYTDESCT

PF01108 // ENSGT00510000049322_Domain_1 (276, 405)

-FKISLRNFRSILSWELKNHSIVPT
HYTLLYTIMSK----------------------------------------------P--
--EDLKVVKNCANTTRSFCDLTDEWRSTHEAYV-TILEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLAID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVMVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KGNLSGNFTYIIDKLIPNTNYCVSVYLEHSDE---QAVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIITVFLI---ALVLTSTIVTLKWIGYICLRN-SLPKVLNF
HNFF-AWPFPNLPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQLI-DPES----EE---EPDL
PEVDV----ELPTMPKDSPQQLEL---------LSGPCERRKSPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--LSSHLE-EMVD-PEDPD--NVQ-SNHLLASGEGTQPT-FPSPSSEGLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLNQHTLFIA
LQFFIPWELTH-----LM---FSHALLEIPV

PF01108 // ENSGT00510000049322_Domain_1 (272, 405)

QSCN-LTMTSHNFQHILSWKSNSIATTPI
YYTVWYKIWST----------------------------------------------V--
--EEWKAVEDCTNITTLSCEITDFYE-IRECYF-INVTGFSGEE

ENSGT00510000049322_Linker_1_3 (405, 422)

KLV--ECVLNFFPISE
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 537)

-ILDPPEISIFNFKDAVNVTVHHPTFLSKLKEIEK----------DFFSSVVIKVESNG
SSSQDL-EV-EMADKENVTVTTDPLIPNSNYCISAQWKLVP----SDKIQSSSKCFTFSP
SQES--EKS-T-----LIPVVFVVCFII--ILLITTFVKTLKNTGYICRKPIPSPKALDF
PPVT---PGPLRLHYEKITVVEIIYKIKKKEMLRE--SDDKSDNEDKSDSDYE---STQR
TGNGYIMNCLTS-----------RSLSQDSTFTQKEG--NPT-GSG---PK-----DPEC
PET------NPPLADAGSAT---------SNQLKAGPDEKGVSRLW--SFIS-EGSVLSS
ESEDCSNFNVNLNTVFVGDPGDNNA--------------------------SEEDDAQI-
--LLPVQE-DKTN-LVDSD--GSE-L--LSQAACGKTP-LLHVPSAEHLWSE-NSSSDES
VTSE--PD-KDQR--GGYLRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------T
SLF

PF01108 // ENSGT00510000049322_Domain_1 (244, 404)

FFLLVCMI---LQFG---SPSAFVEYPRESCT-VNLILQNFRLVLSLELENKSLPPT
HFTFWNAIMSE----------------------------------------------T--
--EAPKVLENCRNITEPSCDVTDKWNGAHETYV-LIVVIYRGD

ENSGT00510000049322_Linker_1_3 (404, 425)

SMPS--YY-------IL
V-RP

PF09294 // ENSGT00510000049322_Domain_3 (425, 537)

EPPEFEIIGFMDHINVTVKFPPVTPKIYGESS-------------KSFVIEERAGE
NMK-THNPK-MDNPTGNFTYVLRDLLPQTNYCVSVYFKAGRM---EDTIKSPFKCTLLPP
GQEA--GLS-D---SATVGIIAV-CFI---TMSTISFIILLKRIGCICLKN-SFPNALNL
HNIL-YWIFPEVPPSEAVDKLEIIPTNKKKKVWNY--DYG-----DESDSDE--EEVPKA
SATGYTTHGLMG-----------RLPHPASDSSANPQEAQLEEGSAAEESDEAGARADAM
AE--L----PTEAEVG----PSED---------RSGPYERKERGIQ-DSFPG-DDSSSVN
GPGDKVIFNVNLNSVFLRALHDDP-----------------------------EEA-SE-
--VLSLAE-DTGHLDEAPH--RTE-SGLLMPGSDSTQLS-QPGISSQVLWTE-DESSETT
DSS--DSD-ADLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MAVLIG
PLCFCQ

PF01108 // ENSGT00510000049322_Domain_1 (247, 404)

FVYL----SIFTTTL-YSLAETSLINSPQKLTMNSQNFQHILSWEAGNNTTVPT
YYHVQYIALSS----------------------------------------------K--
--KEWKDAEECSNTTRLFCNLTKEYDDYENSYI-ALLKSFTEH

ENSGT00510000049322_Linker_1_3 (404, 422)

GVFN--LSSPDFSPYRA
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 538)

-YLGPPIVNLTACPGCINVTVKLPAVYLKE----KSLIDI--Y---KKLDYSTTVESSD
R--KEKIPFRNETSEECFSYVIRSLRLNTNYCVSVAVTASLN---SHSIPSALKCIITKS
TTRK-----GD-GTIPIL-SGGLVSFV---LGVLLIG---LYKGGFICLKS-GPWPKVLE
TTNT-LHCSVHVPDPEIVCSVQIIHKEIIKKEWE----YCDDDDDDDSGSDS-------E
NSDEYTKRGILG--RIVNSHAKSNTFVQQSIDCASAESSSQA------------IKLLDS
D-AEN------SEED--Q---SV----------IKE-NESTSKVLF-HPSSE-VNHSSTS
DLRNSACFNINLSTVMLRDPEKTW------------------------------DESTT-
--LVTHQE-DEVDLQDYCAFEEFE--SKPFTNIDYSKRPDCHNSS--HEWQKPSVS-DES
DTS---------D--SEYIRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR

PF01108 // ENSGT00510000049322_Domain_1 (241, 406)

PLNLFLMVCIS---LVFG---ISHDLPDYTSESCT-FKISLRNFRSILSWELKNHSIVAT
RYTLLYTIMSK----------------------------------------------P--
--EDWKIVKNCANTTRSFCDLTDEWRSTHEAYV-TLLEGFSGNTT

ENSGT00510000049322_Linker_1_3 (406, 423)

LS--NCSRNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPTV-KGNMSGNFTYIIDKLIPNTNYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---ALVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-ALRT
SGGGYTMHGLTV-----------RPLGQTSA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTTPKCSPQRLEL---------LSAPCERRESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQLT-FPSPSSEGLQSE-DAPSDQS
ETSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNASAIR
PFNLYPWVYIS---LLFG---TSHALTXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXK----------------------------------------------P--
--ENMKIVEDCTNITRPICDLTXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXX-XX
X-XXX----XXXXXXXXX

PF09294 // ENSGT00510000049322_Domain_3 (439, 549)

XXXXXXXXX---XXXXXX-------XXXXXXXXXXXXXXXXX
XXXXHNPQI-NGNITGNFNYAMDKLIPNTNYCVSVYFEPKDL---GSIKKSPLKCTLLQP
GQES--ESS-E---SGRLGGIIIVFLI---ATVFISSIIILKRIGYICLRN-DFPKAW--
-------L-------EAVD-VVKIYINRKMKVWDY--SYD-----DESASEKE-A-ASGT
SAGGTVLP-LT------------RHPNRTSASRPCPVGSRLL---------DPDAGEHDP
PEAEV----QLPMARQGA------------------S--LPGRLSPPDPFSR---KGSTR
GSRDRAIFNMNLSSVFVRVLDDDD-----------------------------SKFPPV-
--LASLPE-KTVNLEGLRK--RTQ--------------P-FRGPCAERRWSE--VVSDKS
DSSE--SD-VDLG--GGYVMK-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------

PF01108 // ENSGT00510000049322_Domain_0 (239, 599)

MA
GLCLLLLICHL-----------STSVLAA-LRSLENVQIHSDNFRHILTWEDNNNSSL-V
YYSVQYKDISS----------------------------------------------GWD
S-VST-----CTNITEQRCDLTDYFKNPHGSYI-VQVVSFTHKETSNATTSKKMFIPASH
T-DLGPPLVKLSAQGSNVTINIRPPISYFKGA--PS-MLHDDVY---PILTYGIERWQGD
QKLSD--YD-KMVFEDNYTFVEPFLPPKTNYCVSVKVTLAATNTKGKKFPSTRQCVITSS
AQTA--DSL-S---PYVI-AVVVAILI---LIGLVCVLFALDRAGYICMGWRFFPKVLKS
FPAS---VSMDRNTEEYVCLAPIAPVEILS-------NTE---QEERSASDTG------M
CMQGYAKRNTVLDSAQNDSSEGESSAVQFSI-----ESS-------GQICSSAEKGIP--
------------KEPLLDLCES----------VASGS-----ELPQAADTP---SPSPMM
SNTPK-VLKISLNSVSVGNPEVLGTGCKN-------------------------KMPLIE
EQVDKAAG-DAPNVPQGPHDLRLN-TNILNLGACW-------VPVSGEGSSEEAGTSDES
DADSGAEE-TERLFASDYMSR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLSNRAFSALS
VLNLC

PF01108 // ENSGT00510000049322_Domain_1 (246, 398)

LVVYVS---LQLT---SSSAFEASPNESCT-LNLTLRNFRLVLSWELKNKSIPPT
HYTFWYTIMSK----------------------------------------------L--
--EAPKVLENCTNITESSCDVTDEWSDMNENYV-PII

ENSGT00510000049322_Linker_1_3 (398, 424)

EIYRRDSMKS--HCGDSILA-TD
I-T

PF09294 // ENSGT00510000049322_Domain_3 (424, 536)

VEPPEFEVVGFTDHINVIMKLPPVTPKIYGESI-------WKTLGYTPFVIKEQAGR
SIK-MHKPK-MNNATGNFTYVLRDLLPNTNYCVSVYFEAE------LPVKSPLKCTLLQP
DQES--GSS-D---FA-IGMIIG-CSL---MVVF-LITIMLKRTGYICLKN-TFPKVLNF
HNFL-SWIYSELPPSEAINKVEVIPTNKKKKVWNY--DYG-----DESDSDD---EVPKA
SATGYTMHGLMG-----------KLLNQASDSSASPRESRLEEDSAAEESDAAAAEAAAE
PE--L----GPEAAVGSGFRPSED---------PSGPYERRESELQ-DSFPG-DDSSSVN
GPEDKVIFNVNLNSVFLRALHDDS-----------------------------EEA-SE-
--VLSLAE-DTVHLDEGPH--RTE-SGLLMAGGDGTQLT-HPGFSSQSLWTE-DESSEKT
DTS--DSD-ADAG--DGYIMR-----------

------------------------------------------------------------
---------------MRLVCP-----------------SCLPGPHL--------------
---------------------RPQDPSR----PLPGALHASPLLGVRFCCTPPRPTPP--
---------------HQGCPGHRAL--------ATARYVKVKRRLKIAKMLLSQNAFIV

PF01108 // ENSGT00510000049322_Domain_1 (240, 405)

R
SLNLFLMVYIS---LVFG---ISHDSPDYTDESCT-FKISLRNFRSILSWELKNHSIVPT
HYMLLYTIMSK----------------------------------------------P--
--EDLKMVMNCANTTRSFCDLTDEWRSTHEAYV-TILEGFSGNTTLF--SCSHNFWLAID
------------------------------------------------------------
----HKPEI-RG

PF09294 // ENSGT00510000049322_Domain_3 (493, 536)

NMSGNFTYVIDKLIPNTNYCVSVYFEHSDE---QAVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIITVFLI---ALVLTSAIVTLKWIGYICLRN-SLPKVLNF
HNFL-AWPFLNLPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSDTE-AAAPRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQFI-DPES----EE---EPDL
PEVDV----ELPMTPKGSPQRLEL---------LSGPCERRESPLQ-DPFLE-EDYSSTE
GSRGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHPE-EMVD-PEGPD--NVQ-SSHLLASGEGTQPT-FPSPSSEDLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFMTW---MPKDDRLLRCERKERTYQLTKMLLSRQTLAIR
LLTLC

PF01108 // ENSGT00510000049322_Domain_1 (246, 403)

FTVYVS---LALD---ASHDIPESADENCD-FKLAFRKYQLILSWELKNRSIVPT
HSTFQYTIMSK----------------------------------------------K--
--ESMKTVENCTNITRSFCDLTNVWQDMHETYI-PMVEEFRG

ENSGT00510000049322_Linker_1_3 (403, 424)

ETLLV--QCLGSITA-LN
L-S

PF09294 // ENSGT00510000049322_Domain_3 (424, 537)

FEPPDFGIIGFADHINVVVQFPPVAPTIYGEDL----------HDQASLIIKEHSED
IDKRHEPKI-SGSFSGNFSYVINNLIPNTNYCISVYFEPRSS---RTITKPPLKCVLLQP
AQES--GSS-K---SVKIVIVIV-IFV----SVAISIILTLRQIGYVCLHT-EFPKVLIF
HNFV-VRIFPELPLSEEVNILEVISINKKKKVWGY--NYG-----DESDSEDE-A-PLRT
IAGGYTMHGLPG-----------RLHSQVRTSPASSQASHLG-DPADEESKEPERETQPQ
P--------QPPAAQGPSPGQKEG---------TSEPSERTEGLPQ-DPCPKVDDGNSSG
GSGDKMTFNVDLNSVFLRVLHDDE--------------------------EDSEEA-AL-
--VLPPPE-EVVDLEEDPQ--EME-SSLLVPGGEKLQVL-FPNLPPECLWTG-DDLSDKS
DTSS--SD--VDDIRDGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------HIS---LVFG---ISYILHXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXK----------------------------------------------P--
--QNMTLVKDCTNITRSFCDLTDVWGNVTDTYI-PRVVGFRGGTQLV--NCMGSFFLETD
-MSLDP

PF09294 // ENSGT00510000049322_Domain_3 (427, 484)

PEFEIVYFTDHIDVKVKFQSVTPKILDGEE---------LQFYLAHVIEEQSGG
VVKKXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXX
XXXX--XSS-E---SATIGGIITLFLI---VAVFISTIMILKRIGYICLRN-DFPKVLNF
YKLS-AWVFPELPPLEKVATVEIIHVNRKKKVWDY--SYD-----E-SDSDD-ET-APQV
SAGGYTMHGLR------------PLGPASTSS-AGLQ--------------DQATEELDL
PEPEA--VTEAAMAPGPSPWQSEC---------TSGAHEVSGDLLQ-DTFSE-EGSSPTE
DSGDRIIFNVDLNSVLVRVLDDEDD--------------------------DNSEVTPM-
--LSSLPE-EAVM-PEGPA--ET-DLSLLVARREGTQLP-FPSPSAECLWPE-DAPSDHS
DTSE--SDVVDTG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------

PF01108 // ENSGT00510000049322_Domain_1 (277, 403)

LTMTSHNFQHILSWKLSSNAIIPT
HYTVSYTIMSA----------------------------------------------Y--
--KEWKAVEKCTNITKSSCNMTDIYE-TNETYL-TSVTGFNS

ENSGT00510000049322_Linker_1_3 (403, 422)

KKKLF--ECVFEFLPITD
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 536)

-ILDPPEVSIFYFEDAINVTVHFPESLSIIKNKEK----------LSPYIFDHRLTNYK
PKVFHK-PK-SSNLEENVTIVIDSLMPNSNYCISAHWETFS----NNVPHSPLKCFILSP
NQES--ESE-E---IIAMPLIFATCFII--FPIIIS-VIFLKKTEYICKKKKHFPKALDF
PSII---PGPLQLPYEKVTRADVIEKTKKKKMFNE--SDDKS------DSDNE---STQK
IENNYTMNGFSP-----------RSLSQNSKFTWKEY--NSN-DSD---PD-----ETES
PEF------DPPATDTDSAT---------SYQVKSGPDESRICRIW--SNLS-EDSNFSS
RSEDCFNFNVNLSTVFVGDPGNDTT--------------------------SEEDAAQI-
--LLPVQE-EKIN-LVNSD--EIE-LKHITHATCVKTP-LFHVPSK-DLWSE-NASSDES
VTSE--SE-VDLG--NDYIRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
PL

PF01108 // ENSGT00510000049322_Domain_1 (243, 405)

NLFLMVCIN---LVFG---ISHDLPDDTSESCT-FKISLRNFRSILSWELKNHSIVAT
HYTLLYTIMSK----------------------------------------------P--
--EDLKMVKNCANTTRSFCDLTDEWRSTHEAYV-TIVKGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----KEES----------QFDLSLVIEEQSEG
IVKKHKPAI-KGNMSGNFTYIIDKLIPNANYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLM---ALALISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-AWPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
NGGGYTMHGLTI-----------RPLGQASA---TSTESQFM-DPDS----EE---EPDL
PEVDV----ELPTTPKRSPQQLEL---------LSAPCERRESPLQ-DPFPE-DDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQPT-FPSPSSEGLQSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR

PF01108 // ENSGT00510000049322_Domain_1 (241, 405)

PLNLFLMVCIS---LVFG---ISHDLPDYTSESCT-FKISLRNFRSILSWELKNHSIVAT
HYKLLYTIMSK----------------------------------------------P--
--EDLKIVKNCANTTRSFCDLTDEWRSTHEAYV-TSLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--NCSHNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPTI-KGNMSGNFTYIIDKLIPNTNYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---VLVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-ALRT
SGGGYTMHGLTV-----------RPLGQTSA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTTPKCSPQRLEL---------LSAPCERRESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--VSSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQPT-FPSPSSEGLQSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF01108 // ENSGT00510000049322_Domain_0 (234, 599)

METLMGG
PLRFYPFAYII---CILCAACCSSMPERFPEGPPFELKMESHNFEHILSWQAVTDPNVTA
HYRVQYY---D----------------------------------------------R--
--RNEMIAQNCSYIEHLSCNLTEDFKNVSSEYT-VRVQSFVGTKVFT--SSKLRFVPHID
T-WLGPPEVNISSCLSCINVTVKLPTPHLRNNEKLVSLVDI--Y---EEIEYSITLKTPD
R--EHKMPLE-TTTKETFSTVIRELNPNTNYCVSVTVSASLN---KHSTSSDWKCATAGS
VAQQ-----GY-YSASFA-SAICFALV---LGIVLKC---MHWGGYILQKK-SLPRTLVF
IGGT-IRYSPCTFVTEKTESVEIIYKEIKKKAVGS--SVSDDSDSDDSGSDD-------L
SNHDYTRRNIVR---TPHSSDTTGVFVRCSTSSTCDDGSSQA------------SEHMDD
D-PEV------FEEN--E---MD----------IEK-DQDPGCKLL-QPFPE-ENCTYSS
RSRNNDCFTINLKSVLLGISEDTM------------------------------DNSTA-
--LLSSQG-DTVDWQHRH---AFE--SQLPDDTESVQKPHCLNNS--QEWKDSSSSSNES
DSSD--SD-TDPK--TEYLRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSWNASAIR

PF01108 // ENSGT00510000049322_Domain_1 (241, 405)

SLILFLMVCIS---LAFG---ISRDLPDYANDSCT-IKISLRNFRSIVSWELKNHSVVPT
HYTLTYTIMSK----------------------------------------------L--
--EDMKTVKNCENTTRSFCDLTDQWKREYELYL-VNLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLI--TCTHNFWLPMD
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVDFTSHINVTVKFPSVV----EEEL----------QYDLSLVIEEQSEK
IVKKHKPEI-KRNMTGNFTYVIDKLIPNTNYCVSVYFVSKDQ---ETVIKSPLKCTLRQP
CQES--ESA-E---SAKVGGMITMFFI---ALVLT-SLVTLKRTGYICLRI-SLPRALNF
RNFF-TWPFPELPPLEAMDMVEVIYINRKKKVWDY--NYD-----DESDNETE-A-APRT
SGGGYTMHGLTL-----------RALGQASASSTTSAESQFV-DPDS----EE---EPEL
PEVDT----EPPTMPTCSPQQLEH---------LSGLYERRESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDVEEAPLM-
--IPSHPE-EMVD-PEDPD--NME-SSHVLASGEGTQPA-FPSPSSEGLCPE-DAPSDQS
DTSE--SD-ADLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------MFMTW---MPKDDRLLRCERKERTYQLTKMLLSRQTLAIR
LLTLC

PF01108 // ENSGT00510000049322_Domain_1 (246, 403)

FTVYVS---LALD---ASHDIPESADENCD-FKLAFRKYQLILSWELKNRSIVPT
HSTFQYTIMSK----------------------------------------------K--
--ESMKTVENCTNITRSFCDLTNVWQDMHETYI-PMVEEFRG

ENSGT00510000049322_Linker_1_3 (403, 424)

ETLLV--QCLGSITA-LN
L-S

PF09294 // ENSGT00510000049322_Domain_3 (424, 537)

FEPPDFGIIGFADHINVVVQFPPVAPTIYGEDL----------HDQASLIIKEHSED
IDKRHEPKI-SGSFSGNFSYVINNLIPNTNYCISVYFEPRSS---RTITKPPLKCVLLQP
AQES--GSS-K---SVKIVIVIV-IFV----SVAISIILTLRQIGYVCLHT-EFPKVLIF
HNFV-VRIFPELPLSEEVNILEVISINKKKKVWGY--NYG-----DESDSEDE-A-PLRT
IAGGYTMHGLPG-----------RLHSQVRTSPASSQASHLG-DPADEESKEPERETQPQ
P--------QPPAAQGPSPGQKEG---------TSEPSERTEGLPQ-DPCPKVDDGNSSG
GSGDKMTFNVDLNSVFLRVLHDDE--------------------------EDSEEA-AL-
--VLPPPE-EVVDLEEDPQ--EME-SSLLVPGGEKLQVL-FPNLPPECLWTG-DDLSDKS
DTSS--SD--VDDIRDGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
A-

PF09294 // ENSGT00510000049322_Domain_3 (423, 538)

ILGPPEVNITSCPNCINVTIKLPASHFRAKGKLLSLIDI--Y---EELDYDITLKSLD
G--EHKRPRQ-RTTEEVFSTVIEELYPSRNYCVSVGVTASLN---RNSVPSPWKCVTTDS
EAR---QGYHE-V--AVA-GAVCVSLI---IAAILKC---VHAAGFISPKF-SLPQTLV-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MHLSQNALDIK
SLNLILMV

PF01108 // ENSGT00510000049322_Domain_1 (249, 403)

VIS---LVFG---VSPDWTESSNEACI-SKMTLRNFRSILSWELKNLSIVPT
HYSLSYTVMSR----------------------------------------------D--
--EDMKTVADCTNIKRSFCDLTGVWEDIHEIYL-TLVEGFRG

ENSGT00510000049322_Linker_1_3 (403, 424)

NMLLV--NCTRPFMPAMD
IVS

PF09294 // ENSGT00510000049322_Domain_3 (424, 537)

FEPPEFEIVGFTDHINVLVKFPLVT----EEGL----------QFDLSLIIEEESEG
IVKKHEPKI-KENTSGDITYVIDKLIPNTNYCVSVYLDSKDQ---DTVIKSPVKCTFLHP
GQES--EAS-E---SAKIGGIIILFLM---AAFLTSTIVILKRIGYICLRN-NFPKALNF
HNFS-VWI-PKLPPCEAMDLVEVISINRKKKVWDY--SYD-----DESDSDNE-T-SPRT
SGVGYTMHGLTG-----------RPLSQASASSATSVESQST-DPDS----SD---QPDL
PEAHA----ELPVIPAHSPWQLEH---------ISEPYERRESPLQ-DPFSE--DSSSTE
QSGDRIIFNVDLNSVLMRVPNDDDNND--------------------NDSDNSEEDPLM-
--LLSLPE-ETVD-PEDPH--TME-SSLLLASGEGTQPT-CPSSSSECVWPE-DAPSDKS
DAVE--SD-ADFG--DGYVMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MILSQNTSTIR
SLNLL

PF01108 // ENSGT00510000049322_Domain_1 (246, 404)

LMVCIN---LVFG---ISHDLSDSSKEPCI-LKMTLRNFRSILSWELKNHSIKPT
HYTLWYTIMSE----------------------------------------------L--
--DDMYTVENCTNTTRSFCDLTGMWTQMHETYL-AMVEGFRGS

ENSGT00510000049322_Linker_1_3 (404, 423)

TSLV--SCKHGFLLAMD
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTDHIIVTVKFPSVF----EKEL----------QSAISLIIEEESEG
IVKKHKPEI-KENFSGNFTYVIDKLILNTNYCVSVYFEPRGQ---ETVIKSPSKCTLLQP
GQES--------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR

PF01108 // ENSGT00510000049322_Domain_1 (241, 405)

PLNLFLMVCIS---LVFG---ISHDLPDYTSESCT-FKISLQNFRSILSWELKNHSIVAT
HYKLLYTIMSK----------------------------------------------P--
--EDWKIVKNCANTTRSFCDLTDEWRSTHEAYV-TLLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--NCSRNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPTV-KGNMSGNFTYIIDKLIPNTNYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---ALVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-ALRT
SGGGYTMHGLTV-----------RPLGQTSA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTTPKCSPQRLEL---------LSAPCERRESPPQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHPE-EMVD-PEDSD--NVQ-SSHLLASGEGTQLT-FPSPSSEGLQSE-DVPSDQS
ETSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MFWSPNASAVR
SLHLH

PF01108 // ENSGT00510000049322_Domain_1 (246, 404)

LLVCIS---LVFG---ISHAWLDFTDQPCV-FNMTLRSLRPILSWKLKNHPIVPT
YYKVQHTIMSK----------------------------------------------L--
--DTMKIVEGCTNITRPSCDVMDVLEDIHENYL-FLLEGFRGS

ENSGT00510000049322_Linker_1_3 (404, 424)

SALD--NCSDIFTS-AD
M-Y

PF09294 // ENSGT00510000049322_Domain_3 (424, 537)

FEPPEFEIAGFTDLINVTVKFPPIIPKIFKKEL----------QHSLSLVISEESGG
IVKTHKPKI-TGNIGGNFSYVIDKLIPNSNYCVSVYFEPKFM---GTPIKSPLKCTFLQS
RQESA-ESS-E---SAKIGGIITVSVV---AVVFIATVLTLKRVGYICLKN-KFPKALNF
QNFL-FWVFPELPPSEAVDVVEVICINRMKKLWNY--NYD-----DESDSDDE-T-APRA
NAGGYTTHGLLG-----------RPLNQTSATSATSEESQSA-DGDAKESDVE---EPDS
PEAHA----ESPTAPRPALCP-SP---------TERTDERTESPPQ-DPVPD-GDSSSTG
GSGDRIVFNVDLKSVFMRVLDDD-----------------------------TEDAPVT-
--FSPPPE-DISD-LEDPG--RTE-PTTLAAGGDGLEPP-YPGASSECQWPA-DIPSERS
DTSD--SD-SDVGVGGDYIRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNALAIR
PLNLYPVVYIS---LLFG---ILHAVSVSPD

PF01108 // ENSGT00510000049322_Domain_1 (272, 405)

ESCISFNLTLRNFRLILSWELKNRSIVPT
HYALSYTIMSR----------------------------------------------P--
--AGEMIVEDCINITRSFCDLTDEWDSMTETYV-TTVVGIRGNTTLV--SCWDRVFPALD
-TSLEPPEFEIVGFTNHINVIVEFPPMLVMK----N---------LQTQLSLIIEEKSGS
IVK---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNASAIR
SLNLIL

PF01108 // ENSGT00510000049322_Domain_1 (247, 403)

MVFIS---LVFG---VLRDMPDSSDEPCV-LKITLQNFQSILSWEFKNHSVVPT
HYTSLYTVMSR----------------------------------------------N--
--EAMKTVEGCVNTTRSFCDLTRVWKNIHEVHI-IKVEGFRG

ENSGT00510000049322_Linker_1_3 (403, 423)

STLLV--HCTKDFLPAID
I-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SLEPPEFEIAGFTDHISVMVKFPSDI----VEGL----------QFDLSLVIEEESEG
IVKKHVLKM-KKNMSGNFTYVIDNLIPNTNHCVSVYFESADQ---ATAVQSPLKCTFLQP
GQES--DPS-E---SGKIGGIITIFLI---AVILTSTIIVLKWIGYICLRK-KFPRVLNF
HNFS-AWIFPELPPWEALDTVEVISINRKKKVWDY--NYD-----DESDDDNK-A-APRA
SAGGYTMHGLTV-----------RPPSQASA---ASEEAEFT-DPDS----CE---EPDL
PEAAA----EPPATPGHGPWQLEH---------MSGPYGRRESPLQ-DPFLE-GDSSSTE
QSGDRTIFNVDLKSVLMRFDDS---DD--------------------S---DNSEDPLM-
--LSALLE-ETVG-PEDAD--ERE-SSLLLATGEGTQPA-HLSPSSEHLWPE-DDLSDKS
DTSE--SD-VDFG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLWSQNTSWIR
PHDLYPVVYIG---LMVG---VVSAWPDLSDES

PF01108 // ENSGT00510000049322_Domain_1 (274, 404)

CT-LKVTFRSFRLILSWELKNHSIAPT
HYTLWYTVMSK----------------------------------------------P--
--DDMKIVEHCSNITASFCDLTDVWEVLPETYI-PRVDGFRGN

ENSGT00510000049322_Linker_1_3 (404, 423)

TMLV--SCISDFFLATH
-V

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SLEPPDFDIVGSTNHINVIVKFPPVIPNILNGEL---------LQYYLPLVIEEQSGK
IVKKHHPKL-NGNIIGNVTYVIDKLIPNTNYCVSVYFKSKDM---GAINRSPVKCTFLQP
GQET--ESS-E---STKIGGIIIMFLI---AAVFISTILILKRVGYICLRN-DFPKVLNF
NNLS-SWVFLERPPLETVAFVEVIHVNRKKKVWDY--NYD-----DESDSNDEVA-PP-I
SGGGYTMHGLTG-----------RLLGPASASSATLE-----------DCNQPDAEEPDQ
SEPEA--DTEPLMAAWPSPGQSECC--------KSGAYKERGRLPQ-DPVSE-DDDSASE
ESGDKITFNVNLNSVFVRIPDDD------------------------------SEVPPT-
--SPSFLE-ETAN-PEDSD--ETE-ISFLAASGEGTQPP-FASPSAECPWPE-DALSDKS
DSSE--SD-ADIR--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------HGTLMGG
PLRFYQL

PF01108 // ENSGT00510000049322_Domain_1 (248, 403)

VFV----SILCAACYSSLPEKIPREPPDNLQMTSNNFQHILSWRAHSDPTVPT
YYRVLYS---S----------------------------------------------H--
--SNWKIAKQCSRIVQPFCNLTDDFQVVSDEYS-AFVQSFVG

ENSGT00510000049322_Linker_1_3 (403, 422)

TEVFN--SSLLHFSPLSE
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 538)

-FLGPPEFNLSSCVHCINITIKLPPTHLRKNGKLLSLFDI--Y---NKVNYEITLRTVG
E--EHKRSPE-KVTEEPFSIVIEELYPNRNYCVSVMVTASLN---KHSIPSAWKCITTDS
VAEK-----DY-YGITIA-GAICFSII---LVVILKC---LHLGGYILHKK-SLPDTLVF
TK-M-FSYLPFTFECEEITSVEIIYKEVKKKAEGSVGAVSSEDDSDDSESDA-------M
SNHDYTRRDIVR--RAPQSSDTSPVFVQHSTSSTCDGSSSWV------------SQNPDD
G-PEV------FEEN--E---MD----------AEE-EKDTDSELL-SPLSK-VNCTYSL
RSRSNFCFTINLKSVLLGISEETT------------------------------DSSAA-
--LLSSQE-DAVDWQCAH---AVE--SKLLDDTESTQKPHHLNNS--DVWQNSSGSSSES
DSSD--SD-MDPK--SEYVRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
SLNLVLMEYNCGFQISMP---FFFFSLDYTDESCT

PF01108 // ENSGT00510000049322_Domain_1 (276, 405)

-FKISLRNFRSILSWELKNHSIVPT
HYTLLYTIMSK----------------------------------------------P--
--EDLKMVKNCANTTRSFCDLTDEWRSTHEAYV-TILEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLAID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVMVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPEI-KGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDE---QAVIKSPLKCTLLPP
GQES--ESA-E---SAKIGGIIIVFLI---ALVLTSTIVTLKWIGYICLRN-SLPKVLNF
HNFL-AWPFPNLPLLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQFT-DPES----EE---EPDL
PEVDV----ELPTMPKDSPQQLEL---------LSRPCERRKSPLQ-DPFPE-EDYSSPE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEASLM-
--LSSHLE-EMVD-PEDPD--NVQ-SNHWLASGEGTQPT-FPSPSSEGLWSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQDASLIR
PLNLYLMVYII---LVFG---TLQTLPDVSDEPCI-FKITLRNFRTILSWKLKDHSIVPT
HYTLQYAIMSG----------------------------------------------P--
--EDVITVKDCTNITRSFCDLTDAWVNMSETYT-LRVVGHRGNSTLV--DCEGSLFPLID
-MPLEP

PF09294 // ENSGT00510000049322_Domain_3 (427, 549)

PNFEIAGFTDHINVTVEFPPVLPKIVHGEG---------SSFYLSLVIEEKSGN
IVKKHKPKI-NADIAGNFIYVINELIPNTNYCISVYFEPSNL---GTINRSPVKCTRLQP
EQES--EPS-E---SAKIGALITLFLI---AAVIMSTIVTLKRIGYICLRN-EFPKMLKF
DNFS-AWIFPELPPLELVTVLEVIPVNRKKKVWDY--NYD-----ES-DSDD-EA-ATRT
SAGGYTMHGLAG-----------RTLCPASTSSAGLQ-----------DPEPQ--EETD-
-SPEPEAESESLMAPGPE---SECT--------CENAYERRETVLT-DLFSE-EDSSSTK
GSRDKTIFNVDLNSVFMRVLDDD------------------------------SEVPPV-
--L-SLPE-ETVN-LEDPK--EME-TSLLVASGEGSQPS-FPSPSVESWWHE-DTPSEKS
DTSK--SD-VDTG--DGYIMR-----------

MPDTILSPKDASVNKTAPNSSPMELFRRRGDWLGAHNRQQMLVNNRTFLHSPAVPPARPP
PPALFQPRPRLRPRPRLRPCPRLRPRPRLPPSPRRRHAACAPGALLVGRRSARALTLKTF
LPGGEESR-RRAGIPPA--SRNPAGEPN----SSPSAVRGPPPGQGRFC-PPPAVSVREA
ACGAHPDR--ERPVPESGVAGARGWHLSGAARRELQRCKSQEKTLKIAKMLLSQNAFIVR

PF01108 // ENSGT00510000049322_Domain_1 (241, 405)

PLNLFLMVCIS---LVFG---ISHDLPDYTSESCT-FKISLRNFRSILSWELKNHSIVAT
HYKLLYTIMSK----------------------------------------------P--
--EDLKIVKNCANTTRSFCDLTDEWRSTHEAYV-TSLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--NCSHNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPTI-KGNMSGNFTYIIDKLIPNTNYCVSVYFDHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---ALVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-ALRT
SGGGYTMHGLTV-----------RPLGQTSA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTTPKCSPQRLEL---------LSAPCERRESPLQ-DPFPG-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--VSSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQPT-FPSPSSEGLQSE-DAPSDQS
ETSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------IEPGESIVCFS
NM

PF01108 // ENSGT00510000049322_Domain_1 (243, 404)

FLFFPVHIS---LVFG---ISYVVPDLSDESCT-LKMRFRNFQSILSWELKNRSIVPT
HYTLWYTIMSK----------------------------------------------P--
--EDMKVVKDCINITRSFCDLTDVWVNRTDMYI-SQVVGYREN

ENSGT00510000049322_Linker_1_3 (404, 424)

AVVV--SCMGSFFLESD
-KP

PF09294 // ENSGT00510000049322_Domain_3 (424, 536)

LDPPKFEIVDFTNNISVNVKFRLDSPRIPS-EE---------LQFYLA-FIEEHAGN
SVKRHQPQI-TGNITENFNYVIDKLIPNTNYCISVYFEPKDP---RKINRSPLKCILFRP
RRES--ESS-E---PATIGGILILFLL---AAVCISTVMILKRIGYICLRN-DFPEALNF
YKLS-VWVFPELPPLEKMATVEVIHITRKKKEWNY--NYD-----DESDIEN-EV-APRV
NSGGYTKHGLTG-----------RLCPTSTTA-ASLEDCSLE-DCSLEDCSDPSAEEPYL
PEPKR--DAETPAAPGPGPWQSEG---------TGGGYQTRGTLWQ-DPTSE-EDSDSTE
GSEGRIVFNVNLNSVCVRALEDD----------------------------KDSEVTLM-
--SPSPPE-ETAV-LEEDL--SETESSLLVASEEGTQLP-FTDPSMECLRPQ-DALSDKS
DTSE--SD-VDIG--DGYIVRQVNLKNFN---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------

PF01108 // ENSGT00510000049322_Domain_0 (234, 599)

MEALMDG
ALHFYQLAFV----NILCAACCSSLPEEIPRGPVDNLQMTSNNFQHILSWQAQSDPTVPT
YYRVLYK---N----------------------------------------------Q--
--SNWKIAKQCSRIVQPFCNMTDDFEVFSDEYS-TFVQSFVGTEVFN--SSSITFSPLSN
T-FLGPPEFNISSCLRCINITIKLPPTHLRENGKLLSLFDI--Y---NYLDYEITLKAVD
E--KHKTSCE-KITEDPFSTVIEELYPNRNYCVSVMVTASLN---KHSIPSAWKCITTDS
IAEK--VA-DY-QSITIA-VAVCFSLI---LAVILKC---MHVGGYILQKK-TLPDTLVF
MK-T-FTYLPCTFESEEIASVEVIYNEVKKKAEGSIGAVSNEDDSDDGESDA-------T
SNHDYTRRDIIR--RAPQSSDTSHVFVQRSTSSNCDDSSSWV------------SQNPDD
D-PEV------FEEN--E---LD----------AEE-EKDINSELL-SPLSK-VNCTYSL
RSRSNACFMINLKSVLLGISEETT------------------------------DSSAA-
--LLSSQE-DAVDWQCTH---AVE--SKLLDDIESTQKPHHLNSS--DVWQNSASSSSES
DSSD--SD-MDPK--SEYIRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLWSQNASPIR
PQNLYLVVYIS---LMFG---VLSSLPDLSDQSCT-FKVTLRNFRVILSWELKNHSIVPD
RYTLQYLVISI----------------------------------------------P--
--DHMKTVEHCSNITASFCDLTDVWDVLSETYA-VTVDGFRGNTTLV--TCFIDFFLATH
-ISLEP

PF09294 // ENSGT00510000049322_Domain_3 (427, 549)

PEFDIVDFTDHINVNVNFPPVIPKILDGKV---------LQFYLPLIIEEQSGG
IVKKYNPTL-DENVTGNFTYVIDNLLPNTNYCISVYFKHRNL---EEIHRSPVKCTLLPP
AQDT--GSS-E---SAKIGGIITIFLI---AAVFISTILILKRVGYICLRN-DCPNVLNF
HNMS-SWVFPEMPPLEAVAFVEVIHTNRKKKVWNY--NYD-----DESDSNDETA-APLT
NTGGYTKHGLVG-----------GLLGPTSASSATWE-----------DCLEPYTEERDL
SEPEA--DTEPLMALGPKPGGSEC---------TSGAHEGRGKLLQ-DPFSE-EDSSSTE
ESGDKIIFNVNLSSVFVSALDDD-----------------------------GSEGPPA-
--SPCFPE-ETYN-LEDSH--RLE-TSFLEAPGEGTQPS-FPTPSAECPWPE-DVLSDIS
DSSE--SG-VDTG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR
PLNLFLMGECC---FL--------------------------------------------
------------------------------------------------------------
----------------SYC----------------------------------FLPLCGY
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEEL----------QFDLSLVIEEQSEG
IVKKHKPAI-KGNMSGNFTYIIDKLIPNTNYCVSVYFEHNDE---QAVIKSPLKCTLLQP
GQES--ESA-E---SAKVGGIITVFLI---ALVLISTIVTLKWIGYICLRN-SLPKVLNF
HNFL-ACPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-ALRT
SGGGYTMHGLTV-----------RPLGQASA---TSTESQFT-DPDS----EE---EPDL
PEVDV----ELPTTPKCSPQQLEL---------LSAPCERRESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDNLEEAPLM-
--MSSHPE-EMVD-PEDPD--NVQ-SSHLLASGEGTQLT-FPSPSSEGLQSE-DAPSDQS
ETSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MILRRRSSLSEG
TADILTWVY

PF01108 // ENSGT00510000049322_Domain_1 (250, 404)

IS---LVIG--GSSNSTETPASCSPFTLKMESQNFHHNLTWGLNNCPITPT
RFTVQYTVISQ----------------------------------------------G--
--DNFTEVSECTHTPSFYCDLTDRFTDIEESYI-TQVWGFAGD

ENSGT00510000049322_Linker_1_3 (404, 422)

RVFT--E-NLEFMPIKD
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 537)

-ILGPPEVHIAALEDQINVTVHFPEGLLDDPKKQKAQIPSKPWTLRDFSGFSGTIKSH-
-------SIKIEDVPEVFSSVVEGLFPNTNYCVTADIRIPLN---TNSQPSDLKCIFLAS
TVKS--ES----IKSQIAGGTFVFAFL---LVVGLTCLTALKIGGYICLRR-KCLPKVLD
ISTL-QFYVFQDPLPEKTFPVEII------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MMLLSHGSSAVR
SRNLCL

PF01108 // ENSGT00510000049322_Domain_1 (247, 403)

MVYLS---LMFV---TSHNLPD---GSCN-LKMTFRNFRLILSWELEKQSTVPT
HYTLWYTVMSK----------------------------------------------T--
--DDMEIIESCTNVTTPFCDVTDVWKQAHETYV-LKVQGFRG

ENSGT00510000049322_Linker_1_3 (403, 425)

KAMLF--NCSSSTLSS-N
I-LY

PF09294 // ENSGT00510000049322_Domain_3 (425, 537)

EPPEFEIVGFTDRINVIVKFPPIVPKIYGEEI----------QHHLLLFIKEESMG
IVKMHEPKI-NGNTTGNFNYVIDNLIPNTNYCVSVYFKPKYL---ENRIQSSSKCTFLRL
DQES--ESS-E---YAKISLIITVFSV---VFVFLGTIILLKRIGYICLRD-NFPKVLNF
HNFV-AQIFPGLPPTEAVNAVEVISVNKKKKVWDY--NYD-----DDSDSDHE-V-ALRP
SAGGYTMHGLTS-----------RLLSQVSAASQEP---EME-GSEAEESD-P---YEAE
PEPHP----GPPTVPKPSPC---H---------TSGPYERRESLCQ-DSFPE-DNCSSAG
GSGDRITFNVNLNSVFMRAPDDDD----------------------------SEESP-L-
--VSSLPE-EIINLEEDPD--QME-SSLLVASGERSQLL-DLSPFSQCLWTEEDTPSDRS
DTSD--FD-VDSG-RDGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQEASSIR
PLHLYPWVY

PF01108 // ENSGT00510000049322_Domain_1 (250, 405)

IS---LLFG---TSHALTGFSDEPCI-LKMTLQNFRPVLSWELKNHSIVPT
HYTLWYTIMSK----------------------------------------------S--
--EDMKIVEACTNITSPSCDLAGVWEHMHETYI-PKVVGFRGST

ENSGT00510000049322_Linker_1_3 (405, 423)

ELV--TCLGHLFLATD
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 536)

TFEPPEFEIVGYTDHMNVIVKFPSVA----LEIL----------DY-LSLVIEEQSAD
IVKKHNPKI-NRNITGNFKYVVDKLLPNTNYCVSVYFEPKHL---GTIQKSPLKCTLLKP
GQESATESS-E---SYKIG-IIALFLI---ATAIISSTIILKRTGYICLRK-DFPKVWDF
SNKS-VWIFPEMLLPEAVDSVEVIGIKRKKKVWNY--SYD-----DESDSDNE-E-TPRT
SVVGYTMHGLTG-----------RPLGPASASSS-LLKSQFS-DPDT-----G---EPDL
PEAEP-----LMAVPGPGPGEAGG---------TSGPYQRRESPLQ-DPFSE-EDSNSTE
GSGDRVTFNVDLNSVFMRVIDDED-----------------------------SEVPPT-
--LPSLPE-ETVH-LEDPD--EME-SSL-MPSEEGTQPP-FPVPSVECQWSE-E-PSDKS
SSSE--SD-VDVG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNVSAIG
P

PF01108 // ENSGT00510000049322_Domain_1 (242, 404)

LNLYPVVHIS---LVFG---ISYVVPDLSDESCT-LKMRFRNFQSILSWELKNRSIVPT
HYTLWYTIMSK----------------------------------------------P--
--EDMKVVKDCINITRSFCDLTDVWVNRTDMYI-SQVVGYREN

ENSGT00510000049322_Linker_1_3 (404, 423)

TVVV--SCMGSFFLASD
-K

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

PLDPPKFEIVDFTNNISVNVKFQLDSPRIPS-EE---------LQFYLA-FIEEHAGN
SVKRHQPQI-TGNITENFNYVIDKLIPNTNYCISVYFEPKDP---RKINRSPLKCTLFRP
RRES--ESS-E---PATIGGILILFLF---TAVCVSTVMILKRIGYICLRN-DFPEALNF
YKLS-VWVFPELPPLEKMATVEVIHITRKKKEWNY--SYD-----DDSDIEN-EA-APRV
NSGGYTKHGLTG-----------RLCPTSTTS-ASVEDCSVE-DCSVEDCSDPSAEEPYL
PEPKR--DAETPVAPGPGPGQSEG---------TGGGYQTRGTLWQ-DPTSE-EDSDSTE
GSEGRIVFNVNLNSVCVRALEDD------------------------------SEVSLM-
--SPSRPE-ETAV-LEEDL--NETESSLLVASEEGTQLP-FTDPSMECLRPQ-DALSHKS
DTSE--SD-VDMG--DGYIVRQVNLKIFN---

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---

PF01108 // ENSGT00510000049322_Domain_2 (364, 405)

SWMSAQQCSGTAQLSCELTEEFRNISTEYA-TFVQSIRGTQ

ENSGT00510000049322_Linker_2_3 (405, 422)

VLN--SSVLRFVPLSQ
T

PF09294 // ENSGT00510000049322_Domain_3 (422, 537)

-ILGPPEVNITSCPNCINVTIKLPTSHFRKGGKLQSLIDI--Y---TELDYIITLKSQD
G--EHKRPRQ-RTTEEEFSTVIGELYPSRNYCLSVAITASLN---RNSRPSPWKCVTADS
EAQT--QGYHA-VAVALA-GAVCVSVV---ILAVLRC---VHAAGFILRKI-SLPQTLAF
IR-K-LAYSPWVAEPEKLACVEIIPTEVKSRARGCRGSASEDSDSSDSDSSA-------L
CDHDYTRRAGLGGDRAPRGRATPSSLGQYSVSSSCEHSSSQA------------GDTPAQ
P-QHC------QPQQGHG---GQ----------PEG-AGDTSSELL-SAL----------
SEGSSECFTIGLDTVLLGAPEQDG------------------------------HGSAA-
--AAPAQE-GAAGCHCDP---ALQ--AKLLEDTESEQEAPCSNDF--HEWQNSSSE--ES
DSLD--SD-TEHV--TGYMRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSQNAFIVR

PF01108 // ENSGT00510000049322_Domain_1 (241, 405)

PLNLFLMVCIS---LVFG---ISHDLPDYTSESCT-FKISLRNFRSILSWELKNHSIVAT
HYTLLYTIMSK----------------------------------------------P--
--EDLKMVKNCANTTRSFCDLTDEWRSTHEAYV-TILNGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--SCSHNFWLDID
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVGFTNHINVIVKFPSIV----EEES----------QFDLSLVIEEQSEG
IVKKHKPAI-KGNMSGNFTYIIDKLIPNTNYCVSVYFEHNDE---QAVIKSPLKCTLLQS
GQES--ESA-E---SAKVGGIITMFLM---ALVLTSTIVTLKWIGYICLRN-SLPKVLNF
HNFV-AWPFPNLPPLEAMDIVEVIYINRKKKVWDY--NYD-----DESDSDTE-A-APRT
NGGGYTMHGLTI-----------RPLGQASA---TSTESQFI-DPDS----EE---EPDL
PEVDV----ELPMTPKRSPQQLEL---------LSAPCERRESPLQ-DPFPE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDLEEAPLM-
--ISSHLE-EMVD-PEDPD--NVQ-SSHLLASGEGTQPT-FPSPSSEGLQSE-DAPSDQS
DTSE--SD-VDLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLNLSVVTVQ
SLHFRLLVYIS---LMFG---ISRAWDDFSGKPCV-FKMTLQNLRPVLSWEFKNDSIVPA
YYNLQYTIMSK----------------------------------------------P--
--EAMKTIESCTNITSTFCDLTEAWQDFHENYF-ILVEGFQGAVSLV--NCSDTLTP-LD
L-YIEP

PF09294 // ENSGT00510000049322_Domain_3 (427, 547)

PEFEITDLIDHINVTVKFPSIT----EEQL----------EHYLELIISEETGG
IVKTHKPRI-PKNISGNISYVIEKLIPKSNYCVSVYFEHTF----DKVVKPPPKCTFLPP
DREPXXXXX-X---XXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXX-XXXXXXNF
HNVF-AWILHDLPPSEAMD-VEIICVNRKKKVWDY--YYD-----DDSDSDTE-T-APGG
NAGGYIMHDLLG-----------SPVTQTSGSPAASEGSQSP-DLGTRELDVE---ELNS
PETHA----PP-------TSQVGL---------LSASSERPEGRPQ-TPFPD-GDSCSPV
GSGDRTVFNVDLKSVFMRLLDED-----------------------------PEEAPGR-
--LSPLPE-DISD-LEDHS--NPE-PSLLMSSAEAIMLP-NPSTCSECQWPE-DTPSQES
GTSDSESD-SDVAAGGGYIRR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MVWNQNASLVR
PQNLYLVVC

PF01108 // ENSGT00510000049322_Domain_1 (250, 405)

IS---FVFG---VSSAFPDLSDKFCT-FKVTFRNFRLILSWELKNHSVVPD
RYTLRYTVISR----------------------------------------------P--
--DQVKIVEHCSNTTASSCDLTDVWEVLPETYS-IRVDGFRGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLV--QCSSYLFLVTH
-M

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SLEPPEFDIVGFTDHINVLVKFPPVIPKILGGGV---------LKFYLSLIIEEQSGN
IVKKHNPEL-NENITGNFTYVIDKLLPNTNYCVSVYFKPRNL---GAVHRSPVKCILLQP
GQET--ESS-E---SAKIGGIITMFVI---AAVIVITIIILKRVGYICLRN-HFPKVLNF
YNFS-TWVFPEMPPLETVAFVEVIHVNRKKKVWDY--NYD-----DESDSNDDTA-TPQT
NAGGYTMHGLVG-----------RLLGPASASSATPE-----------DCMEPDAEEPDP
SEPDTDIDTEPLVPSGPSPGQSEG---------TSGAYECRGKQLQ-DPITE-EDSWSTG
GSGDKITFNVNLSSVFMRVLDDD------------------------------LEVPPG-
--LPSFPE-ETYN-LQESH--RLE-TSSLAANGEGTQPL-FPTPSAECQWPE-DVLSDES
DSSE--SD-VDIG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MLLSWNASIIR
SLT

PF01108 // ENSGT00510000049322_Domain_1 (244, 405)

LFLMVCIS---LAFG---IPHYLSDYANESCT-IKISLRNFRSILSWELKNHSIVPT
HYTLVYTIMSK----------------------------------------------P--
--ADMKLVKNCANTTRSFCDLTDEWKSAHELYL-INLEGFSGNT

ENSGT00510000049322_Linker_1_3 (405, 423)

TLF--TCGRIFWLPTD
M-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

SFEPPEFEIVDFTSHMNVTVKFPSVV----EEEL----------QFGLSLVIEEQSEG
IVKKHKPEI-KRSMTGNFTYVIDKLIPNTNYCVSVYFESKDQ---EAVIKSPLKCTLRQP
CQESDSESA-E---SAKVGGIITLFLI---VLVLTSTLVILKRIGYICLRN-RLPKALNF
RNFF-TWPFPELPSLEAMDMVEVIYINRKKKVWDY--NYD-----DESDSETE-A-APRT
SGGGYTMHGLTL-----------RALGQAST---TSAESQFV-DPDS----EE---EPEL
PEVDA----EPPTMPTRSPQQLER---------LSGLCERRESPLQ-DPFAE-EDYSSTE
GSGGRITFNVDLNSVFLRVLDDE-------------------------DSDDVEEAPLM-
--ISSHPE-EMVD-PEDPD--NME-SSHVLASGEGTWPA-FPSPSSEGLCPE-DAPSDQS
DTSE--SD-ADLG--DGYIMR-----------

------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MRSRCTVSAVG
LLSLCLVVSVS---LETI---T

PF01108 // ENSGT00510000049322_Domain_1 (263, 396)

PSAFDGYPDEPCT-INITIRNSRLILSWELENKSGPPA
NYTLWYTVMSK----------------------------------------------D--
--ENLTKVKNCSDTTKSSCDVTDKWLEGMESYVVA

ENSGT00510000049322_Linker_1_3 (396, 423)

IVIVHRGDLTVC--RCSDYIVP-AN
A-

PF09294 // ENSGT00510000049322_Domain_3 (423, 537)

PLEPPEFEIVGFTDHINVTMEFPPVTSKIIQE-----------KMRTTPFVIKEQIGD
SVRKKHEPK-VNNVTGNFTFVLRDLLPKTNYCVSLYFDDD------PAIKSPLKCIVLQP
GQES--GLS-E---SAIVGITTS-CLV---VMVFVSTIIMLKRIGYICLKD-NLPNVLNF
RHFL-TWIFPERSPSEAIDRLEIIPTNKKKRLWNY--DYE-----DGSDSDE---EVPTA
SVTGYTMHGLTG-----------KPLQQASDTSASPEDPLREEDSGAEESDEAGAGTGAE
PQ--L----PTEAGAG----PSED---------PSGPYERRKSVLE-DSFPR-EDNSSMD
EPGDNIIFNVNLNSVFLRVLHDE-------------------------------DA-SE-
--TLSLEE-DTILLDEGPQ--RTE-SDLRIAGGDRTQPP-LPSLPSQDLWTE-DGSSEKS
DTS--DSD-ADVG--DGYIMR-----------