Query Results 

-------------MDSLINK-----ANFE-AMLDPAAGQEQARA----VPP-QPLPGHNE
GSREVSGRGGDFGRCQGPGSLELQLPESPK--------------QPE-AIEEGGASTAAL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-SVVENEAFKSVGWNEDGDAVVIQVDLFQREMLDQRDPQRIFEADDLKS
FTNQLRLYGFRQIRAPGS-----------------QAQP-WGAERMMTYHN-SNFQRGKP
ELLENIWRKGDLRNPAWKPAWQVID-----------DPKKEKKPV-ATRH--------SP
RFPKAW-------------------------RKAR-------------------------
-----------------------------K------EASLARGSRGQKPTVY--SGVWAM
---------KSI-TAGQGMSTPS-------------PQAPRGCS------GEGTPRHATS
TAPGA-----DAVTGEDTEASS--SSAYR--NHX--------------XXMTLYNTCYSI
ALTALSAKTPDEQSDE------E--EQEGSSD--YKTVLCERVRDMPPQ-----------
----

-------------MASECVK-----EHSA-VQVASLVSKEPASK----PLS-HPSPDPKV
NSGQGLDPYGDRALSQDPGSRESQPPEEPSQPPEGRSQPPEEPRRPV-TSEEGTENLLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 248)

FPRKL----W-AIVEDDTFRSVCWGGEGDIMVIEADLFQREVLGRRGAERIFETDSLKN
FIRQLNLYGFSKIRPKDA-----------------SAYS-RGKKRMMIYRN-SNFQKDKP
GLLENICKKGEARSSAQGGTCIPRPLKNPAGRESGASSAKKKKLV-PTRR--------SP
RFHHEVKA------------------E---HVLPQ-------------------------
-----------------------------R------EALDDQGPRGTQPFMP--SGVWAM
---------SSV--SEQPLEKQL-------------PQEPSGPD------GDED---GTP
SSQAT-----AGMEGEGEVPGS--PQGYP--DYC--------------SVMSLYNTCYSI
LLAALSAMSPREPPED-----GE--GEGQGED--YKCALCEQFKDNTGP-----------
----

-------------MAH------ISSEIQDGPPKDESAGSETSISS---SLY-DYT-TGDS
ALRSMIEEYAFQALSEDLVIKRPHCT------------------CSV-SQTDDVNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-HIVESDQFESIWWDETGTCIVINEELFKKEVLERKDPFRIFETKSMKS
LIRQLNLYGFHKNRQTVQRSASLPVFLEEENNI--SLLR-----KLQTYYN-PNFKRGHP
QLLVRMQRRVGINNVSPIP-SLVQG--------------KKK-HA-KASV---KKDDHNS
EFLPEMSGES--------------AFPAST------------------------------
----------------------------SSSVPFIQKPHTSQVVANTIALSP--CDLPTP
S-AISVRHTDQIVVDQSEVLKKL---TSFNWHSQSRYTQVNGHVEDFATTSTSTSRNHIV
SPLQS-----SYSGLMVEPS--KFPDRHS--DMSAHDNPFL-------NLQERGNSWFSV
PTIAYTSASSLSSKLINNQQYVK--TILIKTDLSNRCQIME---PK--------GD----
----

-------------MASQGTD-----QTDE-VKQAPSGDREPATG----VPT-NSSLDPKL
DSREILGTRSDQAISQDPGPQDNPRPQDPN--------------QGI-VHVEENHPLLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 250)

FPRKL----W-MVAEDDAFTSVRWNDEGDTVIIEEDLFQREILQRRGPGRIFETDSLKS
FIRQLNLYGFSKIRPNDP-----------------SVHS-PGNKRMMMYRN-SNFQRNKP
LLIENIRRRGNLRITT-QPGASATT-------------PKRKKQVEATRR--------SP
RIHRNEPTKE----------------G---DRKAQ-------------------------
-----------------------------K------ESPKAQGPSDTWSFVC--SENQSV
---------SSV--AGHATENRH-------------PSEPGSPS------GEGTSRNVLF
VPLAT-----AGGDGAEEPPTS--PPDYP--NYD--------------SVMSLYNTCYSI
LLASLSEMAPHEVPDE-----DE--QQEGSSD--YKCSLCERFKDNPGP-----------
----

-------------MAH------APTEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFNRGCP
HLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVTAETRGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWPSMSQRISNRTTPTR--SGLSSP
S-SPSFRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHRI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NAQAAAHPWFPM
PMATDTSAASLSRPNPQSFSISE--HHPNYH-----------------------------
----

-------------MAH------APSEIQHVSPKDAPTGSDSSTTS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRMKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AISTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSARPPGQIAMAQHAIFNQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHLI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPLS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQSSSISE--HHPNYH-----------------------------
----

-------------MASHSSQ-----KAHT-APLAPLTCGEPAAG----DPH-ESSPDPNV
DSAETLEKQGDQPRSPDSGLHDNLPQQGLK--------------PQI-ANKEENHTFLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 280)

FPRKL----W-RIVEDEAFTSVHWNDEGDMVVIEADLFQTEVLQRRGADQIFETDNIKS
FIRELNLYGFSKISPL--------------------GHS-AGK-KMMIYRN-SNFQKDKP
LLLQNI--------------------------------PKRKKRAVATRH--------SP
RLHHNQCTQE----------------A---DKKVQ-------------------------
-----------------------------K------GTPPVRRTPSRRSFVL--SHLWSM
---------GSV--PRQAGANHL-------------PREEGGPS------GKGTSSNTTS
APPAT-----SGREGTGQMPES--PLEYP--DYD--------------SVMALYNTCYSI
LTAALSFTAPNEAPEA-----EE--EQGESSD--YKCVLCEQVKDKPNP-----------
----

-------------MAEAP------SEMQAVSPNSLSTDLET---SSGEPWCDN-TGQKDS
DLWAIIEESAFQVLAQRFLIKRPPHT------------------LCA-SEPDEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEDGTYIVINEELFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGI--SASC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTVSRGAAPSLPD--------------FKNKHF-RPDL--VKMDDHSL
GVAVQTSERN------LLS--SSSISNVYLRQKPS-------------------------
---------------------------------------LAQGGSDTMDVIR--SDFSLA
T-PSSFRPPEEILTHRPAPLNEV---SSLCMDSQRIFTQANDSTVNFIITSI-TQNRGDM
SHLWN-----SCIEMQGEP---SFQPGFP--HFSSSSSTYSDSKAKGEPELPIHKERVAS
TTLAST--------SN----------HHSSS-----------------------------
----

-------------MASQGTD-----KVYE-VKLAPPGDGEPATG----IPS-DLSPDPNV
DSGEIFEKNEDEAVNRDPGPQDNPQPQAQD--------------HGA-ANVEE--NILGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-RIVEDDAFTSVRWNEDGDAVVIDEDLFQREVLHRRGAERIFETDSLKS
FIRLMNLYGFSKIRASNP-----------------SGHS-LGNKKMMIYRN-SNFQRDRP
LFLDNVQRKGDLKTTTACSGSSATT-------------PKRKKPTAATRH--------SP
RIHHQESTKE--------------------DKKAP-------------------------
-----------------------------R------EAPNAQGPSGTQSFTF--SGIWSL
---------SSV--AGYATENHG-------------PSELAGPS------GEGTSRNVMF
ASPAL-----AGRDGAGELPPA--PPVYP--DYR--------------SVMSLYNTCYSI
LLAALSVMSPNEAPSE-----NE--EHEGSSD--YKCALCEHFKENPGP-----------
----

MAPRKRAAATNARRREAGPRETSNVSVPDIDLAAS--------ASSVPQAR-GKRVAQDA
ALGSMIAENTSQGSCEEPCTKRLRLN------------------LYE-KCSGKANDLSSF
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 248)

FLKKL----W-EIVESNHFQSIGWADDGNSIVIEETFFKREVLARRGRLQIFDIDSMKT
FIRQLHLHGFFIIEGDLPRSAACAKFLADEAAV--STFS-----KFLCYYN-PYFKRYYP
HLLRRFKRSTGIKKRAPGAFTLDLD--------------L------KEGH--------LS
RL--------------PLKKQSGPAVSVCTEHPGSIQ-----------------------
---------------------------------------------------------DAA
P-TSSAA-----------------------------------------------SPYHIA
SSVPN-----SLFPPGLGLD--GGAAGDG-------------------------------
-------------VGR----------QHNLYYRKYRC-----------------------
----

-------------MAH------VSSETQDVSPKDELTASEASTRS---PLC-EHTFPGDS
DLRSMIEEHAFQVLSQGSLLESPSYT------------------VCV-SEPDKDDDFLSL
N

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVESDQFKSISWDENGTCIVINEELFKKEILETKAPYRIFQTDAIKS
FVRQLNLYGFSKIQQNFQRSAFLATFLSEEKES--SVLS-----KLKFYYN-PNFKRGYP
QLLVRVKRRIGVKNASPISTLFNED--------------FNKKHF-RAGA---NMENHNS
ALAAEASEES--------------LFSASK------------------------------
----------------------------NLNMPLTRESSVRQIIANSSVPIR--SGFPPP
SPSTSVGPSEQIATDQHAILNQL---TTIHMHSHSTYMQARGHIVNFITTTT--SQYHII
SPLQN-----GYFGLTVEPS--AVPTRYP--LVSVNEAPYR-------NMLPAGNPWLQM
PTIADRSAAPHSRLALQPSPLDK--YHPNYN-----------------------------
----

---------------LVGVP-----TRHT-VPLAPSTDGEPATG----DTH-P-HPDANV
YSEEVLAKQGDHPESLDLGSQDNP-PQGPN--------------PET-ANKKENNPLLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 248)

FPRKL----W-IIVEDVAFTSVHWNNKGDTVVIKADLFQTEVLQGRGVGRIFETDSIQS
FICELELYEFSKIHPL--------------------GSS-EGKKRMMTYHS-SNFQRDKP
LFLQNIWTKGNPITTAQPAAGTTTP-------------KRKK-------H--------SP
RFHHNESTQE----------------A---DKKAQ-------------------------
-----------------------------K------GAPTAHGTHGQHSFVF--CGLWFM
---------GSV--AMQAG-NHL-------------PREQRSPS------GEGTSSNATS
VPPAT-----DGRDTTGELSES--PPEYP--GYG--------------LVMIMYGTYYSI
VKAAVSVVPPNEAPEV-----EE--EQ-ESSD--YKRALCEQFKDNPSP-----------
----

-------------MTTQGNK-----ERDK-VRLPPSADGEQERE----APS-TSSSGLNV
ESREFPDQHSDQAESQGPGSPDNPQPQDQN--------------QSS-ASVEENNDILGL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 250)

TFPRKL----W-MLVENDAFRSVYWSENGDSVIIDADLFQTEILQRSGAERIFETDSSKS
FIRQLNLYGFSKIRQTDS-----------------SAHS-QENKRMMIYRN-SNFKRDNP
LLLQNIQRKGNFKNTAEPVISSPAP--------------KRKKQAAATRH--------SP
RIHKNNPTEE----------------A---DQNSQ-------------------------
-----------------------------D------DPPNVQGPSSTPAVMF--SSVWAV
---------SSV--VGPPVESST-------------PTQPNVPG------GEGTSQNVTP
APQVP-----AETVGAVAPPPG--PMVYP--DSV--------------SLISLFNTCYSI
LLAALSVMSPNEPLEE------Q--QQETTPE--YCCAFCEHFKDPPPQ-----------
----

-------------MASQNTE-----QEYK-DKLAPSVGGEPTSWG---DPF-SSSPDPNP
DSSEVLYRHEDHAVSQDPGSQVNSPAEDRN--------------QCV-VNTEDNHNLFRF
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MMVEEDTFKSVSWNDDGDAVIIEKDLFQGEVLQRRGTERIFKTDSLKS
FIHQLNLYGFCKTRPSN---------------------S-PGNKKMMIYRN-SNFQRDMP
RLLENIQTKNDFRNTTQQ--RVPAP--------------KRKKLV-PVRH--------SP
RFHHNNAMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFLS--PGMCST
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGTSEDVTF
ASLTTAQGKCTGMESTGEGPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAISVMSPNEPPDE-----EE--E----------------------------------
----

-------------MDSLINK-----ANFE-AMLDPAAGQEQARA----VPP-QPLPGHNE
GSREVSGRGRDFGRCQGPGSLELQLPESPK--------------QPE-AIEEGGASTAAL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-SVVENEAFKSVGWNEDGDAVVIQVNLFQREMLDQRDPQRIFEADDLKS
FTDQLRLYGFRQIRAPGS-----------------QAQP-WGAERMMTYHN-SNFQRGKP
ELLENIWRKGDLRNPAWKPAWQVID-----------DPKKERKPV-ATRH--------SP
RFPKAW-------------------------RKAR-------------------------
-----------------------------K------EASLARGSRGQKPTVY--SGVWAM
---------KSI-TAGQGMSTPS-------------PQAPRGCS------GEGTPRHATS
TAPGA-----DAVTGEDTEASS--SSAYR--NHC--------------ALMTLYNTCYSI
ALTALSAKTPDEQSDE------E--EQEGSSD--YKTVLCERVRDMPPQ-----------
----

-------------MVSQSSD-----ETCA-APLAPSTGGEATAG----------SPDPNV
DSGEALEKLWDQPESPDLGP-NNPPRQGLN--------------PET-ANEEENNAFLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 265)

FPRKL----W-MIMENAAFTPVRWNDEGDTVVIKADLFQTEVFQHRGADRIFETDSIKT
FIHKLNLY-FNKICPS--------------------GRS-AGKKRMMIYRN-SKFQRDKP
LLLQNI-----------------LS-------------PKRKKQVVMTRH--------SP
RFHHNESTQE----------------A---DKKVQ-------------------------
-----------------------------K------GTPTVHRIPRQCSFLF--CGLWFI
---------GSI--AGQARENHL-------------PSELGGPS------GEGMSSNSMS
VSPAT-----AGRDGAGQLPKS--PPRYP--DYG--------------LVM-TYNTYDSI
VKVAISVVAPNEAPEV-----DE--EEEESSD--YTCALCEQFKDNPNP-----------
----

----------------------------------------------METEQ-GEIPNMDD
ELRALVEENAFRALIGVPLAKRSYFP------------------LTNESVAVEENEFFSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 250)

TFPRKL----W-KIVESDRFKSVWWNEDGSCIIIDEKQFREEILENKGPCRIFETDCMKS
FIRQLNLYGFSKLRHDLERSASLDEFLVEEKEA--LPLS-----KLQLYYN-PNFKRGCP
HLLTRLKRRVGVKNTTKPPSLPSQD--------------KSRSIL-KRDH--CGLEDEKS
ALPGQSAKKHAAAATYPISRSSSSSSASCSSSNSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSASSSSSSSASPPSPLPSPSPSSSVSREMDPKIVENQHFSGRFTSSIEFR--SGFSAP
P-LLAGGVH-------HTMLNQLGPFPPFHLARMTSHTQMSMYGVDGTASTS-SSFYHSM
PPVQS-----SFS-----SV--VYPGMYT--ELTTIQTHLS-------SFVPFYGPCYSI
PMVASASAVPMLVPP-----------EEPQTSWYQHCSGCNCGSSSDAHSS--KRDARPD
----

-------------MASQSTD-----QIDE-VKQAPSGDREPATG----VPS-NSSPDPNL
DSREILETHSDQAMSQDPGPRDNMRPQDPN--------------QGA-VHVEENNHRLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 250)

FPRKL----W-MVAEDDALTSVRWNDEGDTVIIEEDLFQREILHQRGPGRIFETDSLKS
FIRQLNLYGFSKIRPNDP-----------------SVHS-PGNKRMMMYRN-SNFKRDKP
LLIKNIQRRGNLRITT-QPGTSTTT-------------PKRKKQVEAMRR--------SP
RIRHNEPTTE----------------A---DRKAQ-------------------------
-----------------------------K------EAPKAQGPTDTWSVTC--SDIHSV
---------SSV--AGHATEVRQ-------------PSEPASPS------GEGTSGNV-V
VPLAT-----AGGDGAEEPPTS--PPDYP--DYD--------------SVMSLYNTCYSI
LLASLSVMAPHEAPDE-----DE--EQEGSSD--YKCALCERFKDNP-------------
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPP-GSSPDPNP
DSSEVLDRHEDQAMSQDPGSQDNSPPEDRN--------------QRV-VNVEDNHNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-TIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRRGAERIFKTDRLTS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYCN-SNFQRDKP
RLLENIQRKDALRNTAQQATRVPTP--------------KRKNLV-ATRR--------SL
RIYHINARKA----------------A---IKMRQ-------------------------
-----------------------------Q------GAPSVQGPSGTQSFRR--SGMWSK
---------KSA--TRHPLGNGP-------------PQEPNGPS------WEGTSGNVTF
TSSAT-----TWMEGTG-ILSS--L-VYS--DNG--------------SVMSLYNICYYA
LLASLSVMSPNEPSDN-----EE--E----------------------------------
----

-------------MAH------IPSEIQDGPPKDESTDSETSIRS---SLY-DYTLTRDS
VLRSMIEEYAFQALSEDLVIKRPCYK------------------YSV-SETDEVNNFLSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 250)

TFPQKL----W-NIVGSDQFESIWWDERGTCIVINEELFQKEVLERKAPFRIFETKTMKS
LIQQLNLYGFSKKRQTFQRSDSRPVFLEEENNI--SLLS-----KLQTYYN-PNFKRGHP
QLLLRMKRRVGINNVSPIS-SLVQD--------------NKK-HV-KASV---NKDDCNS
EFLPEISRES--------------AFSAST------------------------------
----------------------------SL-----KKPHTIQTVTNTNALSP--CDLPNP
S-PISVRQTEQIVVDQPAVLKKL---GIFNWHSHSSYTQVNGHVEDFATTTASTSQNHIV
SPLQS-----SYSRLMVGSS--KFPVRHS--DMSSHDSPFL-------NRQERGNLWFSV
PTITYTSAS---------------------------------------------------
----

-------------MAH------ISSEIQDGSPKDGSTGKDTSIRS---PSC-DHTFTGDS
ELRSLIEEKAFQALSEGSLIKRPHHT------------------FCV-SDPEEDNDFLSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 251)

TFPRKL----W-KITESNHFKSIWWDENGTSIVINEELFKQEVLEKKAPFRIFGTDNMKS
FVRQLNLYGFRKMRPNFQRSASLADFLAEEKTVS-VLIS-----KLQFYYN-PNFKRGCP
QLLARMKRRVKIKNSLPVSHSSVQD--------------FDRKHF-SAGN---NVDNPTS
GLVAETSGES--------------LVSTST------------------------------
----------------------------NLNVPLIRRPSSSQTIANTTPPMR--TDFYPP
S-ATSIRPSEQILSDQHAFLNQL---TTFHMHSQSSCTQANGHIVNFVTTTTCTSRYHII
SPLQN-----SYFGLMVEPS--TFPTTYP--YLPANESLFP-------SLQLAGNPWFPM
PVIPNTSAASLSRSTHQPSSLYI--HHPQ----YN-------------------------
----

-------------MASQSSH-----EARA-ALLILSTDGEPAAG----DTR-DSSPDPNL
DLGEALEKQGDQPKSPDPGLHDNPLQQGPN--------------PEM-AKEEENNAILGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 251)

FPRKL----W-RIVEDAAFTSVHWNDEGDTVVIEADLFQIEVLQRRGMDQIFETDSIKS
FIRELNLYGFRKVRPS--------------------SHS-TGK-KLMIYRN-SNFQRDKP
LLLHNIQRKGNPRTTSQPATGT-TT-------------PKRKKRVVATRH--------SP
QFHHNEFTQK----------------A---GNKVQ-------------------------
-----------------------------K------GMPTARRTPSQCSFVF--SDL-SV
---------GSV--ARRAGENHL-------------PSEQGSPSRA---AGEGTSSNAIS
VPSAT-----AERDSPGKLPES--PPVYP--DYE--------------SVMALYNTCYSI
LMAGLLVMAPDEAPEA-----ED--EQGESSH--YKCALCEQLKNKPNP-----------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTS-G---DPF-SSSPDPNP
DSSEVLDRHKDHAVSQDPGSQVNSPPEDRN--------------QSV-VNTEDNHKER

PF00447 // ENSGT00510000047153_1_Domain_0 (119, 248)

KF
--------------------------------------FNGEVQ--RG---SSKQTACKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDTP
RLLENIQIKDNLRNTAQQATRVPAP--------------KRKKLV-PIRH--------SP
RFHYNNAMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFMS--PGMCSM
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGTSEDVTF
ASLT----TCTGMESTGEVPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAISVMSTNEPPDE-----E--------------------------------------
----

-------------MASPRSH-----EAGP-ATRAPSAEGEP-------------------
-------KRGDGAESPEPGPRDNPPAPGPS--------------RGA-VGSA-NSHGLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 247)

FPRRL----W-MVAEDEAFPSVRWNDAGDAVVIDQELFQREVLQRRGAESILEADSLKG
FIRQLNLHGFRKLRPAGP-----------------SAGS-PGKETMMIYRN-SNFQRDKP
LLVENIQGARL------PRGPSGPG-------------PKRKKQLVPTRR--------SP
RLRPQDPTKE----------------AA--GSKAP-------------------------
-----------------------------K------EAPSAQGPGATRAFTF--SGLWSR
---------SSV--AGQAGAHQP-------------LREQGGPS------GEGTSRNVTL
VPPAT-----AGSDSAEQVPTS--LPVCP--AYG--------------SVLSLYTTFSSI
LLVALP-------------------GQEGSSD--HKSALCESCKDNPSP-----------
----

-------------MAEAP------SEMQAVSPNSLSTDLET---SSGEPWCDN-TGQKDS
DLWAIIEESAFQVLAQRFLIKRPPNT------------------LCA-SEPDEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEDGTYIVINEELFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGI--SASC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTVSRGAAPSLPD--------------FKSKHF-RSDL--VKMEDHSL
GVAVQTSERN------LLS--SSSVSNVYLRQKPS-------------------------
---------------------------------------LAQGGSDTMDVIR--SDFSLA
T-PSSFRPPEEILTHRPAPLNEV---SSLCMDSQRIFTQANDSPVNFIITSI-TQNRGDM
SHLWN-----SCIEMQGEP---SFQPGFP--RFSSSSSTYSDSKAKGEPELPIHKERVAS
TTLAST--------SN----------HHSSS-----------------------------
----

-------------MAH------IPSEIQDGPPKDESTGSETSIRS---SLY-EYTLTRDS
VLKSMIEEYAFQALSEDLVIKRPCYK------------------YSV-SETDEVNDFLSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 250)

TFPQKL----W-NIIESDQFEFVWWDDRGTCIV-INE-LKKEVLERKAPFRIFETKSMKS
----FNPYGFSKKETNF-RSASLPVFLEEENNISFDLAL-----LLQTYYN-PNFKRDHP
QLLLRMQRRVGINNVSPIP-SLVQD--------------NKK-HV-KASV---NQDDCNS
EFLPETSGES--------------AFSVST------------------------------
----------------------------CLSVPFIQKPHTSQIVTNTNALSP--CDLPNP
S-PISVRQTDQIMVNQPAVLKKL---SIFFMHSHSSYTQVNGHIEDFATTTTSTSQNHIV
FPLQS-----SYSGLMVEPS--KFPDRLS--DMSGHDSPFP-------NLQERGNSWFSV
RTITYT-ASSLSSQLINNHHYMK--TMLIKTDLSNTCQIME---PK--------ED----
----

-------------MAAQGCR-----KRYK-VNLAPSVGDKPEGG----VPS-NPVPEPKL
ASGEILDEHGGRDTSEDAGFPDKLEPEGPT--------------PGQ-L-SREESDALQL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 471)

AFPRKL----W-MIVENDAFKSVRWSDSGNTVIIEKDLFQREVLRRRGAERIFETDSLKA
FNRQLNLHGFIKIRPSK---------------------A-LGKTKVMVYRN-CNFKRDQP
LVLQNIKR-------------------------------RRKKLA-ATRH--------SA
RIQQKNAIKE----------------S---KEASP-------------------------
-----------------------------K------NPPDVLGPSPTPSVRS--SSISSV
---------SSV--AEASMEQPP-------------LAQCSVPS------WESTSHRDMF
EPQVS-----AGMVGEGEPLTE--PGGYS--DPS--------------SVMTLYNACYSI
LLAGLSVMAPEEPSDP---------QGDSPSD--YHCSICEQFRDEQAP-----------
----

---------------LVGVP-----TRHT-APLAPSTDGKPTAG----DTP-PFFPNANV
YSGEVLAKQGDQPESLDLGSQDNP-PQGPN--------------PET-ANKEENNTVLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEDAAFTSVHWNNKADTVVIKADLFQTEGLQGRSVDSIFETDSIQS
FICELNLYEFSKIHPS--------------------GSS-VGKKRMMIYHS-SNFQRDKP
LFLQNIQTKGNPIKTAQPTTGTTMT-------------PKR------------------K
KFHHNESTQE----------------A---DKKAQ-------------------------
-----------------------------K------GAPTAHGTHGRHSFVF--CGLWFT
---------GSV--AVQAGANHL-------------PREQGSPS------GEGTSSNAT-
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPA-SSSPDLNL
DSGDILDRHEDQAVSQDSGSQDNPPREEEN--------------QRM-ASMEDNHKLPGF
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKM----W-MMVEKDIFRSVRWNDDGDAVIIEKDLFQRQTLQRSGAEKIFETDSWKS
FIRQLNPYGFCKICPIT---------------------S-PGDKNMMIYHS-SNFQRGKL
WLLENIRRKGDLRNTTQQVTHVPAP--------------KRAKLV---------------
--HHSDARNA----------------A---IEMSQ-------------------------
-----------------------------G------GTHNVQGPSGTQSFTHCSM----Q
H-------RNTV--TGHPPGYGP-------------PQEPNNSN------WEGTSGNVTF
GSLAT-----AWVESTREVPSS--L-VYP--DNS--------------SIMSLDNEWYSI
LLASLLV-----------------------------------------------------
----

-------------MAN------APSEIQGVSPKDAPTGSESSITS---PWC-DNSITGDL
DLKSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDEDSDFLPL
L

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLQRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---NVDNHNS
DVVAETHGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHLI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NPQAAAHPWFPM
PMTTDTSAASLSRLKYKCWPLTP--NLSQVN------RSLE---DI--------ESA---
----

--------------MELSPA-------ETASAADPEELIETSGSPFTDPTGQDQAPAGHA
AGTSIQEEQDSQMFPEEEE-TKGLPR------------------SSSEESTGIARVFSSL
SFPQKL----W-VLVESDQVKSIQWGHGGNCIVIQEKMFKLEVLAREAPARAFQSTCMKN

PF00447 // ENSGT00510000047153_1_Domain_0 (181, 195)

FVRQLNLYGFTKVP

ENSGT00510000047153_1_Linker_0_1 (195, 233)

RHLERS-FLPQFLAEEEAF--AAHR-----KLLLYSS-

PF00447 // ENSGT00510000047153_1_Domain_1 (233, 257)

PHFRRDYP
WLLGHCKRRVAHKRRDVAAPT---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQNSH-----EARA-ALLILSADREPAAG----DTH-DSSPDPNL
DSAEALEKQGDQPKSPDPGLRDNPPPQVPN--------------PEM-ANE-ENNAILGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 251)

FPRKL----W-RIVEDAAFTSVHWNDEGDTVVIEADLFQMEVLQRRGTDQIFETDSIKS
FIRELNLYGFRKICPS--------------------SHS-AGK-KLMIYRN-SNFQRDKP
LLLQNIQRKGNPRTTSQPATSTTTT-------------PKRKKRVVTTRH--------SP
QFHHNEFTQE----------------A---GNKVQ-------------------------
-----------------------------K------GMPTAHRTPSQCSLVF--SDLWSV
---------GNV--ARRAGQNHL-------------PSDQGSPS------GEGTSSKAIS
VPSAT-----AERESPGKLPES--PPVYP--DHE--------------SLMTLYNTCYSI
LMAGLLVMTPEEALEV-----EE--EQGESSD--YKCALCEQLKNKPNP-----------
----

--------------MEISLSETPSVSVPDIDSAAS--------ASSVLQVH-GKADAQDA
ALGSRKAENTSQGSLEEASSKRQPLN------------------LSE-KCSGKANDFSSF

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 154)

SFLKKL----W-EIVESNHFQSIWWADDGNSIVIEETFFKREVLARRGCLQIFNISNMKT
FIRQLHLHRFFIIEGDLPRSASRAKFQADEAAV--STSS-----KFLYYYN

PF00447 // ENSGT00510000047153_1_Domain_1 (232, 248)

-PYFRRDYP
HLLRRFKRSTGIKKRAPGAFSLDLD--------------L------KEGH--------LS
RS--------------PLKKQSGPAASVSVGT----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPS-GSSPDPNP
DSSEVLDRHEDQAMSQDPGSQDNSPPEDRN--------------QRV-VNVEDNHNLFRL
F

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-TIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRRGAERIFKTDSLTS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYCN-SNFQRDKP
RLLENIQRKDARRNTAQQATRVPTT--------------KRKNLV-ATRR--------SL
RIYHINARKA----------------A---IKMCQ-------------------------
-----------------------------Q------GAPSVQGSSGTQSFRR--SGMWSK
---------KSA--TRHPLGNGP-------------PQEPNGPS------WEGTSGNVTF
TSSAT-----TWMEGTG-IPSS--L-VYS--DNG--------------SEMSLYNICYYA
LLASLSVMSPNEPSDD-----EE--E----------------------------------
----

-------------MATQSIE-----EDCE-TNGNPAVDEEPESK----DIP-NSSPGSEA
HSREGLVRQDDQNVIQDQ-----------S--------------QPA-ASEEDNTNLLSL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 246)

FPRKL----W-AIVQNDAFKSVNWTKDGDSILIEVDLFQREVLHLKGAKKIFETDSLKS
FIRQLNLYGFRKISSETS-----------------VASS-GENKKIMIYRN-FNFQRDKP
GLFKYIWGKEDLGNLAKQATCVPIPLSPSQGPIS-----KKKKMS-PTRY--------SP
RFYCKPEED---------------------GVESG-------------------------
-----------------------------K------KNSNNQAHKGNHSFVF--SSVWAM
---------KAI--PGYYLQNQP-------------SGEPSNTT------VEDTSHNIRM
PPTAP------GVQGTEVPSAS--SPGHR--ILH--------------SMMSLYNDCCSA
IFSALSQRPMNESPIE------E--EQEGSSD--YKRVICEPIKNNPHL-----------
----

-------------VAH------VSSEIQDVS-HVGPTDSGNSGRS----LC-DQTFSGDL
DLRSMIEENAFQGLSEESLIKRPCYT------------------HCV-SEPDEDNDFRSL
I-SNKL----W-KMAGSDQFKSIWWDDNGTTIVIDKDVFKKEVLERKAPFRIFETGSMKC

PF00447 // ENSGT00510000047153_1_Domain_0 (181, 193)

FVRQLNLYGFHKVRQNFQRSACLADFLAEGKEV--SVLS-----KLQFYHN-PNFERGCL
I-LVRIKRRVGIKNAFLVS-SLAEE--------------F-KKHF-KGGG---NVDNPNS
DFVADTSGES--------------AFLTFA------------------------------
----------------------------NLNIPLIRKPSASHIIGDTNIPVR--GDFSP-
S-SMSVRPPEQIAVDKRAILNQL---ATVHGHSQSSYTEANSRVVNFITTKTSNSQYSIL
SPIQS-----NYFGLMVEPS--NFPNRYH--NISANERHFS-------KLQPGINPRFPV
PVIADTSATSLSRPIHQPFSVYE--QHPNYN-----------------------------
----

-------------MAH------APSEIQGVSPKDAPTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLIKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEECFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNED--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHRI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQSSSVSE--HHPNYH-----------------------------
----

-------------MAH------VSSEIQIVSPNDGSNDSETSIRS---ALC-DHTYPGDS
ELRSMIEEYAFQALCEETLIKRPRYT------------------FCA-SEPDEDNDFLS

PF00447 // ENSGT00510000047153_1_Domain_0 (120, 425)

M
TFPRKL----W-KIVESDQFKSIWWDENGTSIVINEDLFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFSKMRQNFQRSASLADFLAEEKEV--SVLS-----KLQFFHN-PNFKRGCP
QLLVRMKRRVGIKNASPAS-SLFQD--------------FNKKHF-GADS---HVDNHNS
GFVAESSEES--------------VFPHST------------------------------
----------------------------NVNMPLIRNPATSQIIAKTTAQRR--SNFSPP
S-STLVRSSEQIVMDRYAISNQL---TTFPVHSHSSYTQANTRMVNFITTTTSASQNHII
SPLQR-----SYFERMVQPS--TFPNRYS--YSPVIDGLPS-------TLQPVGNPNFPM
TMIADTSATSLSRSTPQTS-----------------------------------------
----

-----------------STH-----EMRE-AKLAPSEDGQPPIM----VQH-DTSPDPHV
GPREALERHGNQEDSQDPSLQDNPQPQDPN--------------QGA-K-CGRKQILLGL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 419)

SFPRKL----W-RIVEDNSFMSVHWNDDGDTVIIEENLFQKEILCLRGKEQIFEWNSLKS
FICLLNRHGFSKICT---------------------VCS-PGN-RIMIYRN-CNFQRGKP
WLLKNITTQGNQVTH-VCPGTSITL-------------QK-RKNMAPTRH--------SP
RIHQKVSNKE----------------A---EEKAQ-------------------------
-----------------------------E------TGKNEWGPNATQAFEF--SVPQL-
--------------MGSAREVQC-------------PSAVSGSS------GEGTSGSVMF
VPAAT-----AGTDGKGDLPPP-----------K--------------SVMSLHNICYST
LIAGLSVMAPSEDLDQ-----AEEEEHEGSSD--NKCSLCEQFKDNAGP-----------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTS-G---DPF-SSSPDPNP
DSSEVLDRHKDHAVSQDPGSQVNSPPEDRN--------------QS--------------
----VP----W

PF00447 // ENSGT00510000047153_1_Domain_0 (132, 247)

-MMVEEDTFKSVSWNDDGDTMIIKKDLFQREVLQRRGAEKIFKTDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMVKSTTTPIFRDTP
RLLENIQIKDDLRNTTQQATRVPAP--------------KRKKLV-PIRH--------SP
RFHHN-AMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFMS--PGMCSM
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGTSEDVTF
ASLT----TCTGMESTGEVPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAISVMSPNEPPDE-----EE-------------------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSKVLDRHEDHAVSQDPGSQVNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEETFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDKP
RLLENIQKKDDLRNTAQQATCVPTP--------------KRKKLV-ATRR--------SL
RIYHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------GAPSVQGPSGTQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPS------WEGTSGNVTF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLYNICYSI
LLATLSVMSPNEPSDN-----DE--EQEGSSD--YKCKLCEQFRNNASP-----------
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPS-GSSPDPNP
DSSEVLDRHEDQAMSQDPGSQDNSPPEDRN--------------QRV-VNVEDNHNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-TIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAERIFKTDNLTS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYCN-SNFQRDKP
RLLENIQRKDALRNTAQQATRVPTP--------------KRKNLV-ATRR--------SL
RIYHINARKE----------------A---IKMCQ-------------------------
-----------------------------Q------GAPSVQGPSGTQSFRR--SGMWSK
---------KSA--TRHPLGNGP-------------PQEPNGPS------WEGTSGNVTF
TSSAT-----TWMEGTG-ILSS--L-VYS--DNG--------------SVMSLYNICYYA
LLASLSVMSPNEPSDD-----EE--E----------------------------------
----

------------------------------------------------------------
-------------------MNKNPSLQG------------KELSSHF-LSLTEIGDLLCL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 250)

FPKKL----W-KIVESDHFKSIRWDENGDCVVIDEEFFQREVLDRKGLIRIFETSSLKS
FIRQLNLYGFSKLRINVS-----------------SAHSHQGMKKVMIYRN-SNFRRDCP
FLIQRIKRRVGIRNRAQPNPVSPLP--------------KRKKPRVLRR---------QF
SFREVRMARY---R----------KWVM--AKRVK-------------------------
-----------------------------K------KVLKKFGHFQKRSLKT--YALQAR
T-------FENS--AGHSRQIQP-------------RVLPRKAP--------NSTGSSLF
IPQEPAA--SIDPSNMGLLPPS----VYQ--DFTSLNAQIT-------TLMSLCNPWFAM
FVAAASSMPVSEPNEQ----------QVSSSA--HPCPACNCCNGNEAPSSKTVTTQSPH
SSSD

-------------MAEAP------SDMLDVSPNSLSTDSET---SSGDPWCDNNTGQKDS
ELWAIIEESAFQVLAQRFLIKRPPHT------------------LCA-SEPDEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEDGTYIVINEELFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGI--SASC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTVSRGAAPSLPD--------------FKNKHF-RPDL--GKMDDHSL
GVAVQTSERN------LLS--GSSISNVYLRQKPS-------------------------
---------------------------------------LTQGSSDSMDVIR--SDFSLA
T-SSSFRPPEEVLTHRPAPLNDV---SSLHMDSQRIYTQANDSTVNFIITSI-TQNRRDM
SHLWN-----SCIEMQGEP---SFQPGFP--HFSSSSSTYSDSKAKGEPELPIHKERVAS
TTLAST--------SN----------HHPSS-----------------------------
----

-------------MASQSST-----ESCE-AMLGPPASGEAAIE----GLS-SSSLVPNV
DSGKALVQLSEEAVSQAPTRRLQVPGS-QG--------------QVA-VNKQGSDILCGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 251)

FPRKL----W-MIVEDPAFESVCWNEDGDTVIIENDLFQREVLLREDGDRIFETDSIKT
FTRQLNLYGFSKIRSKK------------------SALS-PGNKKMMVKSQ-RQFSRDKP
ALLANIQRKGDQRRFGRQSTCGASP--------------KKRKLV-AARR--------SP
RTQPNKEDEE----------------A---ERRAQ-------------------------
-----------------------------R------EAASAHSPISSQSLMF--SGIWSM
---------SNI--TVSPLRIYA-------------PEEPRGPS------GEGTSSNVLF
APPGT-----AGMQGAGEATSS--PVAYP--DYD--------------SMISLYTTCYSI
LLAALFTMTYNQPLEQ-----------ESPSN--SRCIFCERVRENPPP-----------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSKVLDRHEDHAVSQDPGSQDNSPPEDRN--------------QCV-VNTEDKQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEDTFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDKP
RLLENIQRKDDLRNTAQQATCVPTP--------------KRKKLV-ATRR--------SL
RIYHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------GAPNVQGPSGTQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPS------GEGTSGNVTF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLCNICYSI
LLATLSVMSPNEPSDN-----DE--EQEGSSD--YNCKLCEQFRNNASP-----------
----

-------------MEH------GSSETQGFSPKDELTVSEASTRS---PLC-EHTFSGDS
DLRSMIEENAFQVLSQGFLLKRPCYT------------------VCV-SEPDKDNDFFSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVESDQFKSVSWDENGTCIMINEELFKKEILERKHPYRIFQTDSIRS
FVRQLNIYGFSKIRQNFQRSAFLPTFLAEEKES--SVLT-----KLKCYYN-PHFKRGCP
QLLVRVKRRIDVKNASLTPTLFHED--------------FNQKHF-RAGA---NMENHNP
ALAAEVSEES--------------LFATST------------------------------
----------------------------NLNMSLTRESSVGKIIASSSDPII--SGFLPP
SRSTSIGPSEQSATDQRAILNQL---STIHMHSHSTYMQARGRIVNFITTTT--SQYHII
SPFQN-----CFLGLTLESP--AVPTRYP--VVSVNQAPHP-------NLLPAGNRWLQM
STIADISSSPLSRPATQPSPLDK--YHTNYN-----------------------------
----

------------------------------------------------------------
-----------------------------------------------------------L
R

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-KMLESGKFQSIWWSESGKCVAINRDLFEVEVLGREG-QQVFHTQKIKS
FMRQLNAYGFTKMQRNFQRSASLPEFLAEEAAA--SAHS-----QILYYFN-PSFNRAHP
WLLETCKRRGVLKGRGPEAEKMEER--------------PL-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

---------------LVGVP-----TRHT-APLAPSTDGKPTAG----DTP-PFFPNANV
YSGEVLAKQGDQPESLDLGSQDNPPPQGPN--------------PET-ANKEENNTVLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEDVAFTSVHWKNKGDTVVIKADLFQTEVLQGRGVDRIFETDSIQG
FICELNLYEFSKIHPS--------------------GSS-VGKKRMMIYHS-SNFQRDKP
LFLQNIQTKGNPITTAQPATGTTTT-------------PKR------------------K
KFHHNESTQE----------------A---DKKAQ-------------------------
-----------------------------K------GAPTAHGTHGRHSFVF--CGLWFT
---------GSV--AVQAGANHL-------------PREQGSPS------GEGTSSNATS
VPLAT-----AGRDTTGELSES--LPEYP--GYA--------------SVMIMYSIYYSI
VKAAISVVAPNEAPEV-----EE--EQ-ESSD--YKCALCEQ------------------
----

-------------MAEAP------SEMRAVSPNSLSTDLET---SSCEPWCDN-AGQKDS
DLWAIIEESAFQVLAQRFLIKRPPHT------------------LCA-SEPGEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEDGTYIVINEELFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGI--SASC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTVSRGAAPSLQD--------------FKNKHF-RPDL--GKMDDRSL
GVAVQTNERN------LLS--SSSVSNVYLRQKSS-------------------------
---------------------------------------LALGASDTMDAIR--SDFSLA
T-PSSFRPPEETLTHRPAPLNEV---SPLRMDSQRIFTQANDSTVNFIITSI-TQNRGDM
SHLWN-----SCTEMQGEP---SFQPGFP--HFSSSSSTYSDSKAKGEPELPTHKERVAS
TTLAST--------SN----------HHSSS-----------------------------
----

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQVKEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPSL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVKKKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVVAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIGWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSVSQYHCI
SNFPS-----GYFGLRV----------YQ--NISPTECPVS-------NPQPAAPPWFPM
PMATDTSAASLSRPNPQSSSVSE--HHPIYH-----------------------------
----

------------------------------------------------------------
-----------------------------------------------------DSEEREM
TVKQKT----W-QKSTE

PF00447 // ENSGT00510000047153_1_Domain_0 (138, 250)

NQFKIVWWPSHPKCWI-QENMTKKEVLERKAPFRIFETKSMKS
LIRQLNLYGFSKKRQTFQRSASLPVFLEEENNI--SLLS-----KLQTYCN-PNFKRGHP
QLLLRVQRRVGINNVSQIS-SLVQD--------------NKK-HV-KASV---NEDDRNS
EFIPEISRES--------------AFSAST------------------------------
----------------------------SLRVPFIQKPHTIQIVTNTNALSP--CDLPNP
S-PISVRQTEQILVDQPAVLKKL---SIFNWHSHSSYTQVNGPIEDFATTTTSTSQNHIV
SPLQS-----TYSGLMVEPS--KFLVRHS--DMSGHDNPFP-------NLQETGNSWFSV
PTSTYTSASSLS------------------------------------------------
----

-------------MAH------ISSEIQDGPPKDESTDSETSIRS---SL----------
---SMIEEYAFQALSEDLVIKRPHYT------------------YSV-SETDDGNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-NIVESDQFESIWWDETGTCIVINEELFKKEVLERKDPFRIFETKSMKS
FIRQLNLYGFHKNRQSVQRSASLPVFLEEENNI--SLLS-----KLQTYYN-PNFKRGHP
QLLVRMQRRVGINNVSPIS-SLVQG--------------NKK-RA-KASV---KKDDHNS
EFLPEMSGES--------------AFPAST------------------------------
----------------------------SLSVPFIQN-----------ALSP--CDLPNP
S-AISVRHTDQIVVDQPEVLKKL---SIFNWHSQRSYTQANGHVEDFATTTTSTSQNHIE
SPLQS-----SYSGLMVEPS--KFPDRHS--DMSAHDNPFL-------NLQERGSSWFSV
KLI-NTSASSLSSKLINNHHYVK--TILIKTDLSNTCQIME---PK--------GD----
----

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASVLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWRSMSQRISNTTTPTR--SGLSSP
S-SPSFRPPGQIAMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYRCI
SYFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQSSSVSE--HHPNYH-----------------------------
----

-------------MAD------VSSETQDISPKVKSTGSEASTRF---LLG-EHIFSEDS
DLRSIIEENAFQVLSQGSLIKSPGYT------------------ICV-PELDKDSDFISL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 184)

FPRKL----W-KIVENDQFKSISWGEDGTCIVIHEELFKKEILERKDPYRIFKAESIKS
LVRQSIITQ--------------------------------------------ISNCGCP
QLLVKMKRRIGIRNASLVSTLFTEG--------------FKKKHF-RAGA---NTDNHNS
GLIAETSGER--------------SFSTST------------------------------
----------------------------NLNKPLIRKSV-SQRIASLPDTTR--SGFPPT
PSSTSFGPREHIATNQNTILNHL---ASIHMQSHSTYIQANDHILNCITTTT--SQYQII
SPSQN-----SLLGLIVKPL--TFPSRYP--EVSVNEAPYP-------NLLPAGKLWLPG
PTIADTSAYPPFKPAFQPSSLGK--YHPNYN-----------------------------
----

----------------QSIY-----EIHE-AKLAPSEDGQPPIM----AQY-DTSTEPHV
GPREALERHGDQEESQDPSPQDNPQPQDPN--------------QGA-TNVEGNNILLGL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 483)

SFPRKL----W-KIVEDDAFTSVRWNDDGDTLIIEENLFQREILCRRGEEQIFESKSLKS
FIRLLNLHGFSKIRPGNS-----------------SVCS-PGN-KMMIYQN-CNFQRDKP
WLLENIMRKGNRMTR-ALPRTSSTP-------------PKRKKKMAPTRH--------SP
RIRYNDGNND----------------A---EEKAQ-------------------------
-----------------------------R------KAKNDWEPSAAEFFKY--LGLRP-
--------------ISSAMEVQC-------------PSKAGGPS------GEGMSGNVMF
VPLAT-----ARTDGTGDLPTS--PTNNP--LHG--------------SVMSSCNVCYST
LMAGLSVMAPLEDPDK-----EE---EEGSSN--NKC-----------------------
----

-------------MASQSTD-----QIDE-VKQAPSGDGEPATG----VPT-NSSLDPNL
DSREILETHSDQAMSQDPGPQDNLRPQDPN--------------QGA-VHMEENHHLLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 283)

FPRKL----W-MVAEDDAFTSVRWNNEGDTVIIEEDLFQREILHRRGPGRIFETDSLKN
FIRQLNLYGFSKIRPNDP-----------------SVHS-PGNKRMMIYRN-SNFRRDKP
LLIENIQRG--------------------------------NKQVAATRR--------SP
RTCQNEPTIE----------------T---DRKAQ-------------------------
-----------------------------K------EAPKAQGPTDTWSVMC--SDVHSV
---------SSV--EGHATENRE-------------PSEPGSPS------GEGTSRNVLF
ESMAT-----GGGDGAEEPPTS--PPDYP--DHD--------------SVMFLYNTCYSI
LLASLSVMAPPEAPDE-----DE--EQESSSD--YKCALCEHFKDNPRS-----------
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPS-SSSPDPNV
DSRELLDRHEDQAVSQDSGSQDNPQPEDQN--------------QRV-ASMEDNRNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MMVEEDTFQSVNWNDDGDAVIIEKDLLQREILQRRGAEKIFKTDSLKS
FIRQLNLYGFRKIRAST---------------------S-PRDKNVMIYHN-SNFQRGKP
WLLENIRRNGDLRNATQQATHVPAP--------------KRSKLV-PIRH--------PL
QIHHSNDKDA----------------A---IEMSQ-------------------------
-----------------------------G------GTPNVQGPSGTQSFPCPHPGTWPI
Y-------VNPI--TGHPPGYGP-------------PQEPNDPN------REGTSGNDAF
ASSAT-----AGMESAREVPSS--L-VCP--DIS--------------SLMFSCNVCYSI
LLASLLVMTPNEPSDD-----EE--EEE--------------------------------
----

---------------NKNTP-----EMQE-AKLALSEDGQPPIM----AQY-DTSPDPHV
GPREALESQGDQEDSPGPSPQDNPQPQDPS--------------QGT-ANVEGNNILLGL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 459)

SFPRKL----W-RIVEDDAFSSVCWNDDGDTVIIDENLFQREILCRRGEEQIFESKSLKS
FICLLNRHGFSKICPSNS-----------------SVFS-AGN-RMVIYRN-CNFQRGKP
WLLENITTQGNQVMR-VCPGTSATP-------------PKRKKKMAPTRH--------SP
RSHHQNGGKE----------------A---KQKTQ-------------------------
-----------------------------E------TGKNDWGTNANQAFKF--SVPQP-
--------------MGSAREVQC-------------PSAASSSC------GEGTSGNVMF
VPRAT-----AGTDGTGDLPPT--PPNEP--LQG--------------SVMSLYNICYST
LITGLSVMAPSEDPDQ-----AEE-EQEGSSD--NKCSVCEQFKDNAGP-----------
----

-------------MAH------ISSEIQDGPPKDESTDSETSIRS---SLY-DYT-TGDS
VLRSMIEEYAFQALSEDLVIKRPHYT------------------YSV-SETDDGNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-NIVESDQFESIWWDETGTCIVINEELFKKEVLERKDPFRIFETKSMKS
FIRH------------VQRSASLPVFLEEENNI--SLLS-----KLQTYYN-PNFKRGHP
QLLVRMQRRVGINNVSPIS-SLVQG--------------NKK-RA-KASV---KKDDHNS
EFLPEMSGES--------------AFPAST------------------------------
----------------------------SLSVPFIQKPHTSQIVANTSALSP--CDLPNP
S-AISVRHTDQIVVDQPEVLKKL---SIFNWHSQRSYTQANGHVEDFATTTTSTSQNHIE
SPLQS-----SYSGLMVEPS--KFPDRHS--DMSAHDNPFL-------NLQERGSSWFSV
KLI-NTSASSLSSKLINNHHYVK--TILIKTDLSNTCQIME---PK--------GD----
----

-------------MESQSSN-----KPCA-APLAPSTDGEPTAA----HPP-D-HPDPNV
DSEEALEKWWDQPESPDPGPQDNP-PQGPN--------------PAT-ASEEVNNAVLGL
SLP

PF00447 // ENSGT00510000047153_1_Domain_0 (124, 250)

RKL----W-MIVEDAAFTSVHWNDEGDMVLTEADLFQTEVLHHTCTDRIF--DSIKS
FICELNLHGFSKIHHS--------------------GCS-AGKKRMMIYHY-SKFQRDKP
LLLQNISTPKRKK------QA--------------------------------------V
VTRCSPCTKE----------------A---DKQVQ-------------------------
-----------------------------K------GGSTVHGTPGQCSFEF--LA--FG
---------LSV--VGRPRSSHL-------------PSEQGCPS------GEGTSSNAMS
VPLAT-----AGRDSAGELPKSRNCPRYP--DYG--------------PVMTLYNTYDSI
VRGAISVVAPNEAPEA-----EE--EQEES----SKCALCEEFKDKPNP-----------
----

------------------------------------------------------------
----------------------PPHS------------------PCQQEGAGQASVFSAL
SFPQKL----W-VLAESDQVKSIWWGHGGNCLVIEEQLFMVEVLAKEAPVRAFGCTGMK

PF00447 // ENSGT00510000047153_1_Domain_0 (180, 195)

S
FVRQLNRYGFTKVPRDLERSPSLPEFLAEEEAT--AAQR-----KLLLYSC-PLFRRDDP
GLLEHCKLRAARKRRAEAAPS---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSEVLDRHEDHAVSQDPGSQVNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEETFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDKP
RLLENIQRKDDLRNTAQQATCVPTP--------------KRKKLV-ATRR--------SL
RIYHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------GAPSVQGPSGTQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPS------WEGTSGNVTF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLYNICYSI
LLATLSVMSPNEPSDN-----DE--EQEGSSD--YKCKLCEQFRNNASP-----------
----

-------------MAEAP------SEMQAVSPNSLSTDLET---SSGEPWCDN-TGQKDS
DLWAIIEESAFQVLAQRFLIKRPPHT------------------LCA-SEPDEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEDGTYIVINEELFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGI--SASC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTVSRGAAPSLPD--------------FKNKHF-RPDL--VKMDDHSL
GVAVQTSERN------LLS--SSSISNVYLRQKPS-------------------------
---------------------------------------LAQGGSDTMDVIR--SDFSLA
T-PNSFRPPEEILTRRPVPLNEV---SSLCMDSQRIFTQANDSTVNFIITSI-TQNRGDM
SHLWN-----SCIEMQGEP---SFQPGFP--HFSSSSSTYSDSKAKGEPELPIHKERVAS
TTLAST--------SN----------HHSSS-----------------------------
----

-------------MAH------ISSEIQDGPPKDESTGSETSIRS---SLY-DDTLTGDS
VLSSMVEEYAFQALSEDLVIKRPQYT------------------YSL-SERDEVNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-NIVESDQFESIWWDETGTCIVINEELFKKEVLERKKPFRIFETKSMKT
LIRQLNLYGFNKKRQTVQRSASLPVFLEEENNM--SLLT-----KLQTYYN-PNFKRGHP
QLLVRMQRRVGINNVSPIF-SLVHD--------------NKK-RV-KASV---NKDDHNS
EFLPEMSGES--------------AFPAST------------------------------
----------------------------SLRVPFIQKPHTSQIVANTIALSP--CDLPTP
S-AISVRHTDQTVVDQPEVLKKL---TIFNWHSQSRYTQVNGHVEDFATTTTSTSRNHIV
SPLQS-----SFFGLMVEPS--KFPARHS--DMSSHDSPAP-------ILQERGNPWFSV
PTIGYTSASSLSSKLINNHHYMK--TMFIKTDLSNMCQIME---PK--------GD----
----

-------------MASQGTD-----KVYE-VKLAPPGDGEPATG----IPS-DLSPDPNV
DSGEIFEKNEDEAVNRDPGPQDNPQPQAQD--------------HGA-ANVEE--NILGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-RIVEDDAFTSVRWNEDGDAVVIDEDLFQREVLHRRGAERIFETDSLKS
FIRLMNLYGFSKIRASNP-----------------SGHS-LGNKKMMIYRN-SNFQRDRP
LFLDNVQRKGDLKTTTACSGSSATT-------------PKRKKPTAATRH--------SP
RIHHQESTKE--------------------DKKAP-------------------------
-----------------------------R------EAPNAQGPSGTQSFTF--SGIWSL
---------SSV--AGYATENHG-------------PSELAGPS------GEGTSRNVMF
ASPAL-----AGRDGAGELPPA--PPVYP--DYR--------------SVMSLYNTCYSI
LLAALSVMSPNEAPSE-----NE--EHEGSSD--YKCALCEHFKENPGP-----------
----

-------------MAH------ISSEIQDGTPKDESTGSETSVRS---SLY-DYTLTRDS
VLRSMIEEYAFQALSEDLVIKRLCYT------------------NSV-SETDELNDFLSH
FHKTLE----YSCKVQCPQTDHRCVDESG

PF00447 // ENSGT00510000047153_1_Domain_0 (150, 249)

VCIVISEELLK-KVLKRKEPFRIFETNSMKR
IFTQVNLYGFNKKQQTFQRSASQADFLEENI----SLLS-----KLQTYYK-SNSKQGHP
QLLVRMQRRLGINNVSLIS-SLVQD--------------NKT-YV-KARV---NKDDHNS
DFLRETSGES--------------AFSASR------------------------------
----------------------------TLNVPYIPKPHSSQIFDNTSAVSP--CDLPSP
S-PISLRQTDQIVVDQPAVFKTL---SIFNWHSHSSYTQVNGHVEDFATTTTSTSQNHIV
SPLQS-----SYSGLMVESS--KFPVTYSNINMSAHDSPFP-------ILQETGNSWSSM
SMIAYTSASSLSSQLINNHHQMK--AMLIKTDLSNKCQIME---PK--------ED----
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPS-GSSPDPNP
DSSEVLDRHEDQAMSQDPGSQDNSPPEDRN--------------QRV-VNVEDNHNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-TIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRKGAERIFKTDSLTS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYCN-SNFQRDKP
RLLENIQRKDALRNTAQQATRVPTP--------------KRKNLV-ATRR--------SL
RIYHINARKE----------------A---IKMCQ-------------------------
-----------------------------Q------GAPSVQGPSGTQSFRR--SGMWSK
---------KSA--TRHPLGNGP-------------PQEPNGPS------WEGTSGNVTF
TSSAT-----TWMEGTG-ILSS--L-VYS--DNG--------------SVMSLYNICYYA
LLASLSVMSPNEPSDD-----EE--E----------------------------------
----

-------------MASQNTE-----QEYK-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSEVLDRHKDQVVSQDPGSQDNSPPEDRN--------------QCV-VNTEDNHNLLG-
-----L----W-MMVEEDTFKSKDLFAEGN--------------------

PF00447 // ENSGT00510000047153_1_Domain_0 (171, 249)

-LRNRQRLKS
FIHQLNLYGFCKTRPR-------------------------------IYHN-SNFQRDKP
RLLENIQRKDDLRSTAQQATYVPTP--------------KRKKLV-ATRR--------SL
RIYHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------RAPIVQGPSGSQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPR------WEGTSGNATF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLYNICYSI
LLATLSVMSPNEPSDN-----DE--E----------------------------------
----

-------------MAH------ISSEIQDGPPKNESAGSETSIRP---SLY-DYT-IGDS
VLRSMIEEYAFQALSEDLVIKRPRYT------------------YSV-SQTDDVNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-NIVESDQFESIWWDETGTCIVINEELFKKEVLERKDPFRIFETKSMKS
LIRQLNLYGFHKNRQTVQRSASLPVFLEEENNI--SLLR-----KLQTYYN-PNFKRGHP
QLLARMQRRVGINNVSPIS-SLVQG--------------NKK-HA-KVSV---KKDDHNS
EFLPEMSGES--------------AFPAST------------------------------
----------------------------SLSVPFIQKPHTSQVVANTRALSP--CDLPTP
S-AISVRHTDQIVVDQSEVLKKL---SILNWHSQSRYTQVNGHVEDFATTTTSTSGNHIV
SPLQS-----SYSGLMVEPS--KFPDRHS--DMSAHDSPFL-------NLQERGNSWFSV
PTIAYTSASSLSSILINNHQYVK--TILIKTDLPNRYQIME---PK--------GD----
----

-------------MAH------VSSETQDVSPKDELTASEASTRS---PLC-EHTFPGDS
DLRSMIEEHAFQVLSQGSLLESPSYT------------------VCV-SEPDKDDDFLSL
N

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVESDQFKSISWDENGTCIVINEELFKKEILETKAPYRIFQTDAIKS
FVRQLNLYGFSKIQQNFQRSAFLATFLSEEKES--SVLS-----KLKFYYN-PNFKRGYP
QLLVRVKRRIGVKNASPISTLFNED--------------FNKKHF-RAGA---NMENHNS
ALAAEASEES--------------LFSASK------------------------------
----------------------------NLNMPLTRESSVRQIIANSSVPIR--SGFPPP
SPSTSVGPSEQIATDQHAILNQL---TTIHMHSHSTYMQARGHIVNFITTTT--SQYHII
SPLQN-----GYFGLTVEPS--AVPTRYP--LVSVNEAPYR-------NMLPAGNPWLQM
PTIADRSAAPHSRLALQPSPLDK--YHPNYN-----------------------------
----

-------------WLVRVQR-----RACA-APLAPSTDGEPTAG----DLP-DSSLDANV
DSGEVLGKQGDQTESPHPGSQDNLPPQGPN--------------PET-ANEEENNTVLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 251)

FPRKL----W-RIMEDAAFTSGSWNDEGDMVVIETDLFQTEVLQHRGTDRIFDTDSIKS
VICELNLYGFSKIYPL--------------------DHS-AGKSRMMIYRN-SNFQRDKP
LLLQNIQRKNNCLAHQ--------------------------------------------
------WSNN----------------Y---PKEKE-------------------------
-----------------------------N------GNPTAHGSPSRHSHVF--SGLRST
---------GSV--AGWARANHL-------------SSEQGSPS------GEGTSSNGTS
VLLAT-----AERDSAGELPKS--PPEYP--GYG--------------SVMTLYNTCYSI
LMAALLVMAPNEALEV-----EE--EQEESSD--YKCALCEQFKDNPNP-----------
----

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDEDSDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDQFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNED--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMRQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIAMAQHAVFNQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYRCI
SYFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPVS-------NPQPAAPPWFPM
PMATDTSAASLSRPNPQSSSISE--HHPNYH-----------------------------
----

--------------MNLSWT-VRHQENPDTSPRARTTDSETCGGSKLSPEC-EQTSAGDC
DLRSVIEENVFQPLAEGPLVKKRRYI------------------W---PDGSDSNDFFAF

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 242)

TFPKKL----W-KIIESDQFQSIWWNNDGNSIVIDEELFKKEVLESKGPFRIFETDCMKS
FIRQLNLYGFSKIRYEFQRSASLADFLAEEKAV--SAMN-----KLQFYHN-PNFKRCCP
HLLVC-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQVEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKH----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRR---------------------------------KRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHVVNFITTTTSISQFRCI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQSSSVSE--HHPNYH-----------------------------
----

-------------MASQNTE-----QEYE-AKLAPSVGGQPTSG----GPS-SSSPDPNP
DSSEVLDRHEDQAMSQNPGSQDNSPPEDRN--------------QRV-ANVEDNPNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEDTFKSVSWNDDGDAVIIEKDLFQREVLQRRGAEKIFKTDSLKS
FIRQLNLYGFRKTRPSN---------------------S-PGNEKMMIYRH-SSFQRDNP
RLLENIQRNDNLRNTAQQATRVPTP--------------KRKELV-ATRR--------SL
RIYHINARKE----------------G---IRMCQ-------------------------
-----------------------------R------GAPSVQGSSGTQSFRR--SGMWFK
---------KRA--TWLHLGNEP-------------PQEPNGPS------GEGTSGNVTF
ASSAT-----TWMEGTGQVPSR--L-VYS--DNG--------------SVMSLYNICYYV
LLASLSVMSPNEPSNN-----EE--EQEGSSD--YKYRPCEQFRNNASP-----------
----

-------------MAN------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASVLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSFRPPGQIAMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYRCI
SYFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQSSSVSE--HLPNYH-----------------------------
----

-------------MDSQSSN-----KPCAAAPLAPSTDGEPTAG----HPP-D-HPDPNV
DSEEALEKWWDQPKSPDPGPQDNT-PQGPN--------------PAT-ASEEVNDAVLGL
SLP

PF00447 // ENSGT00510000047153_1_Domain_0 (124, 250)

RKL----W-MIVEDAAFTSVHWNDEGDMVLTEADLFQMEVLHHTCTDRIF--DSIKS
FIRELNLHGFSKIHHS--------------------GCS-AGKKRMMIYHY-SKFQRDKP
LLLQNIPRRTVPA------TGTT--------------------------A--------TP
KRSKQWCTKE----------------A---DKQVQ-------------------------
-----------------------------K------GASTVHGTPGQCSCIW------FM
---------DSV--VGRPRSSHL-------------PSEQGCPS------GEGTSSNAMS
VPLAT-----AGRDSAGELPKSRNCPRYP--DYG--------------PVMTLYNTYDSI
VRGAISVVAPNEAPEA-----EE--EQEESSEVPEKCALCEEFKDKPNP-----------
----

-------------MAEAP------SEILDASGHDVSADSET---PSSPPLCDD-TGQGDS
DLWAIIEESAFQVLAQRFLIKRSSHS------------------LCA-SEPDEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEAGTYIVINEELFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGV--SASC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTASRGAAPSPPE--------------FKNKHF-SPDL--DNMDDQSL
GVAVQTRKRN------LLS--SPSISNVYLRQKSS-------------------------
---------------------------------------TAQGDTDTMDGIR--RDFSLA
T-SSSFRPPEKILTHHPAPLNEV---SPLHMDSQRIYTQANDSTMNFIITSI--QNHRDV
SHLWN-----SCIEMQAEP---SFQPGYP--HFSSSSSTYSDSKAIGESKLPIYKERVVS
TTLASA--------LN----------HHPSS-----------------------------
----

------------------------------------------------------------
---------------------------------------------------------LPL
C

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPEKL----W-KMLESDQFQSIWWSEGGKCVAINKDLFEVEVLGRGVCQRVFNTQHIRS
VIRQLNLYGFTKVQQDFERSASLPEFLAEEAAA--SAHS-----QVLYYYN-PRFNRAHP
WLLGTCKRR---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MEH------VSSETQDVSPEDELTDSEASTRS---PLC-ENTFLEDS
DLRSMIQENAFQVLSQGL-VKRPRYT------------------ACD-SEPDKDNDFFSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 249)

TFPRKL----W-KIVESDQFKSISWDENGTCIVIYEEHFKKEILERKAPYRIFQTDSIRS
FVRQLNIYGFSKIRQNFQRSAFVATFLAEGKES--FVLS-----KLKFYYN-PHFKRGCP
QLLVRVKRRIGVKNTSLISTLFSED--------------FNRKHF-RAGA---NIDNRNS
ALAAKASEES--------------LFSTSK------------------------------
----------------------------NLNMPLTRESSVRQITANSSGPIR--SGFPHP
SPSTSVGPSDKIATDQHSILNQL---TTIHMHSYSTYMQARGHIVNFITTTT--SHYHII
SPLQN-----RYLRLLVEPS--AILRRCH--VVSVNEAPYP-------NLLPAGNSWLQM
PIRADTLTAPHSRPALQPSLLDK--YHPNYN-----------------------------
----

------------------------------------------------------------
-----------------------------------------------------------L
C

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 250)

FPEKL----W-KMLESDQFRSIWWSEGGKCVAINKDLFEVEVLGRGVCQRVFNTQHIRS
VIRQLNLYGFTKVQQDFERSASLPEFLAEEAAA--SAHS-----QVLYYYN-PRFNRAHP
WLLGTCKRRAALKQKGLCAAGLDER--------------PLQK-P-RGS-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQSSH-----EAQA-AQLAPSTDGEPAAG----DSC-DSSADRNP
---------RSTPPR-------QSAPQGLN--------------PKT-AE-EENNVILRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-RIVEDAAFTSTCWNDE----VIEVDLSQMEVLQRRGLDQIFETDSIKS
FISELNLYEFSKIHPL--------------------GRF-AGKKMMMIYPN-SNFQRDKP
L-LQNIWRKGNPRTIAQPTASATAT-------------IKTKN----PQG--------N-
------------------------------------------------------------
--------------------------------------TTCSQNPQLVLICV--SGLWSM
---------GSI--VRRAGRNHL-------------PSEQGSPS------GEGTSSNATS
VPPAT-----FGRDGTGELPKS--PSEYP--DYN--------------LVMTLHKTCYSI
LMVALSVMAPNEAPEV-----EE--EQGESLD--YTCVLCALQGQAQSLNC---------
----

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQVEEKAFQALSEGSLTKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRMKYASPVSASLLHG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSFRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHVVNFITTTTSISQYRCI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQTSSVSE--HHPNYH-----------------------------
----

-------------MAH------APTEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHLI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTACPVS-------NPQAAAHPWFPM
PMATDTSAASLSRPNPQSFSISE--HHPNYH-----------------------------
----

-------------MASQSSQ-----KAHT-APLAPLTYGEPAAG----DPH-ESSQDPNV
DSAETLEKQGDQPKSPDSGLHDNLPQQGLK--------------PQI-ANKEENHTFLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 283)

FPRKL----W-RIVEDEAFTSVHWNDEGDMVVIEADLFQTEVLQRRGADQIFETDNIKS
FIRELNLYGFSKISPL--------------------GHS-AGK-KMMIYRN-SNFQKDKP
LLLQNI--------------------------------PKRKKRAVATRH--------SP
RLHHNQCTQE----------------A---DKKVQ-------------------------
-----------------------------K------RTPPVRRTPSRRSFVL--SHLWSI
---------GSV--PRQAGANHL-------------PREEGGPS------GKGTSSNTTS
APPAT-----SGREGTGQMPES--PLEYP--DYD--------------SVMALYNTCYSI
LTAALSFTAPNEAPEA-----EE--EQGESSD--YKCVLCEQVKDKPNP-----------
----

-------------MEH------VSSETQDVSPEDELTDSEASNRS---PLC-EHTFPEDS
DLRSMIEENAFQVLSQGSSLKRPRYT------------------ACD-SEPDKDNGFFSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVESDQFKSISWDENGTCIMINEELFKKEILERKAPYRIFQTDSIKS
FIRQLNLYGFSKIQQNFQRSAFVATFLAEEKES--FVLS-----KLKFYYN-PHFKRGCP
QLLVRVKRRIGVKNTSLISTLFNED--------------FNRKHF-RAGA---NMDNHNS
ALAAKASEES--------------LFSTSK------------------------------
----------------------------NLNMPLTRESSVRQMTANSSGPIR--SGFPHP
SPSTSVGPSDEIATNQHSILNQL---TTIHMHSYSTYMQARGHIVNFITTTT--SHYHII
SPLQN-----RYLRLLVEPS--AIPRRCH--VVSVNEAPYP-------NLLPAGNPWLQM
PVRADTLTAPRSRPALQPSLLDK--YHPNYN-----------------------------
----

-------------MAH------IPSEIQDMLPKVESSGSE-TIKS---PLC-DYTLTEDS
VLRSMIEENAFQALFEEVVIKMPRYK------------------FSV-SETDELNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-KLVESDQFKSIWWDESGTSIVIHEEAFKKEVLERRAPLRIFETDSMKS
LVRQLNLYGFKKKQHTFQRSASLADFLEEKSNV--SVLS-----KLQIYHN-PNFKKGYP
QLLLRMKRRIGIKNVSPIA-SLNQD--------------YKKKNV-KARG---NIDNCNS
SSLPETSGES--------------AFSAST------------------------------
----------------------------SLSVPFLLKPYTRQTIANTSALSP--CDFPSP
S--TSVRQTEKIVMDQPTVLNQL---NIFNRLSHRSYTQANGLMENFATTTTCTSQNHIV
SPLQS-----SYVGLMVHPY--KFPFRYS--YMTAHDSPFP-------NLQQRGNSWSPV
PRIHDTSSSSLSRSTHQKSSLYE--NH------PN-------------------------
----

-------------MASQSND-----EIHQ-VKLA-PGDGESTIE----APS-SSSLDLNL
DSREVLENQEEPAVSRDPGPQDNPQPQAPN--------------HGA-ASVGD--DLFGL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 471)

SFPRKL----W-RIVEDDAFPSVRWNDDGDTVVIDKDLFQREILHRRGPERIFETDSLKG
FIRLMNLYGFSKLRPNNP-----------------SVYS-PGNQRTMIYRN-SNFQRDRP
MLLENIQRKSDLRTGTGWSGSSATP-------------PRRKKQVAATRR--------SP
-IHHKESTKE--------------------DEAAP-------------------------
-----------------------------K------EAPSVQGPSGTRSLTS--SGIWSL
---------SSV--AGYAMENRG-------------PSEQGGPS------GEGTSRNVMF
VPPAT-----AGRDGAGELPTA--PPVYP--DYG--------------SVMSLYNTCYSI
LVAALSVMSPIEAPSE-----NE--GQEGSSD--YKCALCKHFKDNPGP-----------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTS-G---DPF-SSSPDPNP
DSSEVLDRHKDHAVSQDPGSQVNSPPEDRN--------------QSV-VNTEDNH-----
---

PF00447 // ENSGT00510000047153_1_Domain_0 (124, 248)

RKL----W-MMVEEDTFKSVSWNDDGDTMIIKKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDTP
RLLENIQIKDDLRNTAQQATRVPAP--------------KRKKLV-PIRH--------SP
RFHHNNAMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFMS--PGMCSM
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGTSEDVTF
ASLTTAQGKCTGMESTGEVPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAISVMSTNEPPDE-----EE-------------------------------------
----

--------------MELSAA-------ETASAADPEELIETSGSASTDPTGHDQAPAGHA
AGTSIQEEQDSQMFPEEEE-TKGLPS------------------SSSEESASLASVFSCL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 205)

FPQKL----W-VLVESDQVKSIQWGHGGNCIVIQEEMFKVEVLAREAPARAFESTCMKS
FVRQLNLYGFTKVPQHLERS-FLPQFLAEGEAF--AAHR-----KVSTSIV-LHTN----
QLLQNLERRMFH------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MAH------ISSEIQDAPPKDESTDSETSIRS---SLY-DYT-TGDL
VLRSMIEEYAFQALSEDLVIKRPHCT------------------YSV-SETDDANDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-NIVESDQFESIWWDDTGTCIVTNEEPFKKEVLERQEPFRIFETKSMKS
FIRQLNLYGFHKNRQTVQRSASLPVFLEEENNI--SLLS-----KLQTYYN-PNFKKGHP
QLLVRMQRRIGINNVSPIS-SLVQG--------------NKK-HA-KASV---KKDDRNF
EFLPQTSGES--------------AFPAST------------------------------
----------------------------SLSVPFIQKPHTSQIVTNTSALSL--CDLPTP
S-AISVRHTDQIVVDQSEVLKKL---SIFNWHLQSSYTQVNGLVEDFPTTTTYTSRNHIE
SPLQS-----SYSGLMVEPS--KFPDRHS--DMSAHDSPFL-------NLQERGNSWFSV
PTIAYTSASSLSSKLINNHHYVK--TILIKTDLSNTCQIME---PK--------GD----
----

-------------MVH------IPSEIQDGPPKDESTGSEASVRS---SLY-DYTLTRDP
VLRSMIEEYALQTLSEDLVIKSPCYK------------------YSV-SETDEVKDFLSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 249)

TFPQKL----W-NIVESDQFESIWWDERGCIVI-NEELFKKEVLERKAS---LETKNMKS
----LNPYGFSKKRQTFQRSAALPVFLEEENI---SLLS-----RLQTYYN-PNFKRDHP
QLLLRMQRRFGINNVSPIS-SLVQV--------------NKK-HV-KTSV---NKDDCNS
EFLPETSGES--------------AFSASI------------------------------
----------------------------CLSVPFIQEPHTSQIVTNTNALSP--CDLPNP
S-PILVRQTDQIVVDQPAVLKKL---SIFNWYSHSSHTQVNGHVEHFATTATSTSQNHFV
SPLQS-----SYSRLMVEPS--KFPVRHS--DMSGHDSPFP-------NLQERGNSWFSV
PTT----ASSLSSQLIN-NHYMK--TMLIKTDLSNTCQIME---PK--------ED----
----

-------------MAH------APTEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHRI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPVS-------NPQAAAHPWFPM
PMATDTSAASLSRPNPQSFSISE--HHPNYH-----------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTS-G---DPF-SSSPDPNP
DSSEVLDRHEDHAVSQDPGSQDNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 248)

FPRKL----W-MIVEEDTFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDTP
RLLENIQIKDDLRNTAQQATCVPAP--------------KRKKLV-PIRH--------SP
RFHHNNAMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFMS--PGMCSM
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGTSEDVTF
ASLTTAQGKCTGMESTGEVPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAISVMSPNEPPDE-----EE-------------------------------------
----

-------------MASQSME-----EKYE-PELAPSVGGEPASG----VPS-NSSTDPNL
DSREVLDRPGDHAVSPDPGSQDNLPLEDQS--------------QHV-ANMEDNTDLRGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVENDIFKSVHWSEDGETVIIEDDLFQREILRRRGAEKIFETDSLKS
FIRQLNLYGFSKIRPNNS-----------------SVHA-PGNKRMMIYSN-SNFQRDKP
ELLENIQKKGYLRNTALKASCAPTL--------------KRKKLV-ATRH--------SP
RIHHNNAKKE----------------A---NQKPQ-------------------------
-----------------------------M------GAPNAQGPSVTQSFMF--SGVCPM
---------NSI--SGHPQENYP-------------THEPHGPG------GEGTSGNATF
APLAT-----APMEGAGEVAAS--PQVIP--DYG--------------SVMSLYNTCYSI
LLAALSVMAPNEPPE-------E--EQEGSED--YKCALCEHFKDNPTP-----------
----

---------------SQSSH-----EAQA-AQLAPSTDGEPAAG----DSC-DSSPYRNV
-----LEKQGEQPER-------QSAPQGLN--------------PKT-AE-EENNAILRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 250)

FPRKL----W-KIVEDAAFTSTCWNDE----VIEVDLSQMEVLQRRGLDQIFETDSIKS
FISELNLYEFSKIHPS--------------------GRS-AGKMMMMIYPN-SNFQRDKP
L-LQNIWRKGDSRTIAQPTASATAT-------------IKTKK----TGQ--------SP
RLHQNQYTRE----------------A---DKKVH-------------------------
-----------------------------K------GTPPAHITPSWCSFVF--SGLWSM
---------GSI--VRWAGRNHL-------------PSEQGSPS------GEGTSSNATS
VPPAT-----FGRDGTGELPKS--PSEYP--DYN--------------LVMTLHKTCYSI
LMVALSVMAPNEAPEV-----EE--EQGESLD--YTCVLCVHFTDKPNP-----------
----

-------------MVSESSH-----EARA-ALLAPSTDEEPAAG----DPS-DSSPDPNV
DSKEALEKQGDQPESPDPGLHDNLPPQGQN--------------PEM-ANEEENNAVLG

PF00447 // ENSGT00510000047153_1_Domain_0 (120, 252)

L
S-----------QIMEDAAFTSVHWNNEGDMVVIKADLFQMEVLQHRGTDRIFETNSVKS
FTHELNLYGFSKICPP--------------------GCS-AGKKRMMDLSH-SNFQRDKP
VLLQNIQRKDDSRTTAQPTTGSIVT-------------PKRKKRAVATRH--------SP
QLHHNQCAQE----------------A---GKKVQ-------------------------
-----------------------------K------RSPAAHRT-SRRSFVL--SHLWST
---------GSV--ARWAGGNHL-------------PSEQGGPS------GEGTSSNAMS
VHPAT-----AGRDSPGELPES--PPEYP--GYE--------------SVMALYNTCYSI
LTAALSVMAPNKAPEV-----EE--EQRESSD--Y-CVLCEQVKDKPNP-----------
----

-------------MASQSSH-----KAHT-APLAPLTCGEPAAG----DPH-DSSPDLNV
DSGETLEKQGDQPKSPDPGLHDNLPPQGPK--------------PEM-ASKEENNTFLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 283)

FPRKL----W-RIVEDEAFTSVRWNDEGDMVVIEADLFQTEVLQRRGADQIFETDSIKS
FIRELNLYGFSKISPS--------------------DHS-AGK-KMMIYRN-SNFQRDKP
LLLRNI--------------------------------PKRKKRAVATRH--------SP
RLHHNQCTQE----------------V---GKKVH-------------------------
-----------------------------K------GTPPARRTPSRRSFVL--SHLWSM
---------GSV--ARRAGANHL-------------PREQGGPS------GKGTSSNTTS
APPAT-----SGRGSTGQMPES--LPEYP--DYD--------------SVMALYNTCYSL
LTAALSFTAPNEAPEA-----EE--EQGESSD--HTCVLCEQVKDKPNP-----------
----

-------------MDSLINK-----ANFE-AMLDPAAGQEQARA----VPP-QPLPGHNE
GSREVSGRGRDFGRCQGPGSLELQLPESPK--------------QPE-AIEEGGASTAAL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-SVVENEAFKSVGWNEDGDAVVIQVDLFQREMLDQRDPQRIFEADDLKS
FTDQLRLYGFRQIRAPGS-----------------QVQP-WGAERMMTYHN-SNFQRGKP
ELLENIWRKGDLRNPAWKPAWQVID-----------DPKKEKKPV-ATRH--------SP
RFPKAW-------------------------RKAR-------------------------
-----------------------------K------EASLARGSRGQKPTVY--SGVWAM
---------KSI-TAGQGMSTPS-------------PQAPRGCS------GEGTPRHATS
TAPGA-----DAVTGEDTEASS--SSAYR--NHC--------------SLMTLYNTCYSI
ALTALSAKTPDEQSDE------E--EQEGSSD--YKTVLCERVRDMPPQ-----------
----

-------------MAH------APSEIQGVSPKDAPTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLIKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNED--SAWN-----KLQFYHN-PNFKRGCP
NLLVRMKRRVRVKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHRI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPVS-------NPQPAAHPWFPM
PMATDTSVASLSRPNPQSSSISE--HHPNYY-----------------------------
----

-------------MASQSSD-----EACA-APLAPSTDGEPTAG----DLP-DSSLDANV
DSGEVLGKQGDQTESPHPGSQDNLPPQGLN--------------PET-ANEEENNTVLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-RIMEDAAFTSGSLNDEGDMVVIETDLFQMEFLQHRGTDRIFDKDSIKS
VICELNLYGFSKIHPL--------------------DHS-AGKNRMMIYHN-SNFQRDKP
LLLQNIQRKGYPRTTAQPVNGATTT-------------PKKKKR--------------SP
RFHHNESTQE----------------A---DKKVQ-------------------------
-----------------------------N------GNPTAHGSPSRHSHVF--SGLWST
---------GSV--AGWARANHL-------------SSEQGDPS------GEGTSSNGTS
VLLAT-----AERDSAGELPKS--PPEYP--GYG--------------SVMTLYNTCYSI
LMAALLVMAPNEALEV-----EE--EQEESSD--YKCALREQFKDNPNP-----------
----

-------------MASQNTQ-----QEYE-AKLAPSVGGEPTSG----GPS-SSSPDPNL
DSREVLDRHDDQAVSQDSGSQDNPPSDDQN--------------QRV-ASMEDNRNLFSL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MMVEEDTFQSLSWNHDGDAMIIEKDLFQREILQRRGAEKIFKTESLKS
FIRQIHLYGFRKIRPST---------------------S-PRDNNMMIYHN-SNFQRGKP
WLLENIRRKGNLRKATQQATHVPAA--------------KRLKLV-AIGH--------PL
HIHHSDAKDA----------------A---IRMSQ-------------------------
-----------------------------G------GSPNVQGPSGTQSFTY--AGMWPK
---------NTI--TGHPPGSGP-------------PQEPNDPN------WEGTSENVIR
ASSAT-----IWMKSTRKVPRS--L-VYP--DNS--------------SVIFLYSDCHSI
LSASLLPMTPNEPPDD-----EE--EQ---------------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSGG---DPF-SSSPDPNP
DSSEVLYRHEDHAVSQDPGSQVNSPPEDRN--------------QCV-VNTEDNHNLFRF
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MMVEEDIFKSVSWNDDGDAVIIEKDLFQREVLQQRGTEKIFETDSLKS
FIHQLNLYGFCKTRPSN---------------------S-PGNKKMMIYCN-SNFQRDMP
RLLENIQTKDDFRNTAQQ--RVPAP--------------KRKKLV-PIRH--------SP
RFHHNNAMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFLS--PGMCSM
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGTSEDVTF
ASLTTAQGKCTGMESTGKVPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAILVMSPDEPPDE-----EE-------------------------------------
----

-------------MASPRSH-----EAGP-ATRAPSAEGEPAPG---------SSPDPGG
DSRETPEKRGDGAESPEPGPRDNPPAPGPS--------------RGA-VGSA-NSHGLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 247)

FPRRL----W-MVAEDEAFPSVRWNDAGDAVVIDQELFQREVLQRRGAESILEADSLKG
FIRQLNLHGFRKLRPAGP-----------------SAGS-PGKETMMIYRN-SNFQRDKP
LLVENIQGARL------PRGPSGPG-------------PKRKKQLVPTRR--------SP
RLRPQDPTKE----------------AA--GSKAP-------------------------
-----------------------------K------EAPSAQGPGATRAFTF--SGLWSR
---------SSV--AGQAGAHQP-------------LREQGGPS------GEGTSRNVTL
VPPAT-----AGSDSAEQVPTS--LPVCP--AYG--------------SVLSLYTTFSSI
LLVALPVTAPNEAPEG-----DE--GQEGSSD--HKSALCESCKDNPSP-----------
----

-------------MAH------VSSEIQDVFPKVGPTGSGNSGRS---LLC-DQTFSGDL
DLTSIIEENAFQTLSEESLVKTPCYT------------------HCI-SEPEEDNEFRSL
IFPRKL----W-KMFGSDQFKSIWWDDNRTSIVIDEDVFKKEVLERKAPFRIFETGSMKS
L

PF00447 // ENSGT00510000047153_1_Domain_0 (182, 193)

VRQLNLYGFSK

ENSGT00510000047153_1_Linker_0_1 (193, 232)

VRQNFQRSVFLADFLAEK-KK--SVLS-----KLQFYHN

PF00447 // ENSGT00510000047153_1_Domain_1 (232, 251)

-PSFKRGCP
QLLVRIKRRVAIKNASLVS-LLSQD--------------FNKKHF-KGGG---NFGKHNS
DFVAYTSGES--------------AFLPSP------------------------------
----------------------------NLNMALIRKPSTGHVIGDTNTPIR--GDFSPP
S-SVSVRPPEQIAVNQCAILNQL---TTVHGHSQSSYTEANDHVVNFITTTTSTSQYSSL
SPLQ--------------------------------------------------------
------------------------------------------------------------
----

-------------MPR------VSAETQDVSPKDESTGSEASSGS---PLC-EHIIPGDS
DLRSMTE--DFQVLPQGSLIKRPHYY--------------------V-SEPDKDNDFPSL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 263)

TFPSKL----W-KIVESDQFKSNSWDKNETCIVINEELFKKENLEIKAPYRIFQTDSMKS
LI-QLNLYGFSKIQQNFHRSAFLANFLAEEKES--VLS------KLHVFLF-HHR-----
--------------------PFEAT--------------FRQLHF-QPCL---LSSDN-F
APT------S--------------SWSRDS------------------------------
----------------------------QLLC----------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTS-G---DPF-SSSPDPNP
DSSEVLDRHEDHAVSQDPGSQDNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 248)

FPRKL----W-MIVEEDTFKSVSWNDDGDTMIIEKDLFQREVLQQRGAERIFETDSLKS
FIHQLNLYGFCKTRPSS---------------------S-PGNKKMMIYHN-SNFQRDTP
RLLENIQIKDDLRNTTQQATRVPAP--------------KRKKLV-PIRH--------SP
RFHHNNAMKE----------------A---------------------------------
--------------------------------------NNIQGPSDTQSFMS--PGMCSM
---------NSI--TGHSLGSGP-------------PQEPNDPS------GEGISEDVTF
ASLTTAQGTCTGMESTGEVPST--L-VYP--DYD--------------CVMSLYNTRYSI
LSVAISVMSPNKPPDD-----EE-------------------------------------
----

-------------MAEAP------PEIPDASPHDVSADPET---PSSRPLCED-TGQGDS
DLWAFIEESAFQVLAQRFLIKRPPHT------------------LCA-SEPDEDSNLFSM
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVGSDKFKSIWWDEAGTYIVINEELFKREVLERKAPFRIFETDSMKS
LVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGV--SPSC-----KLQFYQN-PNFLRDCP
HLIERMKRRIGIKTASRGAAPSLPD--------------FKNKHF-SPDL--DNMDDHSL
GV--QTSESN------LLS--RSSISNVCLRQKPS-------------------------
---------------------------------------TAQGDSDTMDGIR--RDFSLA
T-SSSYRPPEEILTHRPAPVNEV---SPLHMDSQRIYAPANDNPVNFVITSI-TQSHRDV
PHLWK-----TCVEKPAEPS--PFQPGFR--HFSSRSPTFSDSKPRGEPKLPTYKERVAS
STLAST--------SN----------HHPSS-----------------------------
----

-------------MATQNSE-----ERCK-VRLAPSVGGEPEGR----APS-TSSSGPNV
ESREFPDRHSNQAESQGPGSLDNPQPQDQN--------------QSS-ASVEGNNNVLGL
A

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 250)

FPRKL----W-MIAENNAFKSVRWNDSGDTVIIEADLFQMEILQRRGADRFFETDSLKG
FIRQLNLYGFSKIGQTDS-----------------SDHA-PGTKRVMIYRN-SNFKRGNS
LLLRNIQRKGNFKNNAQPENSGPTS--------------KRKKQVTATRR--------SP
RSHKNNSMQE----------------A---RRTPQ-------------------------
-----------------------------V------NPPNVQGPSSTSTVMF--SSIWAV
---------SSI--VGPPMGSTL-------------PSQPNIPG------GEGTSQNVRS
APQAP-----TQPAGAEAPPPG--PVVYP--DSV--------------SIISLFNICYSI
LLAAMAVMSPDEPLEE------Q--R-ESPSD--YHCTLCEHFQDNPAP-----------
----

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQVEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFNRGCP
HLLVRMKRRVRMKNASPVSASLLQG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHVVNFITTTTSISQYRCI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQSSSVSE--HHPNYH-----------------------------
----

-------------MAH------ISSEIQDGPPKDESTGSETSIRS---SLY-DYT-TGDS
VLRSMIEEYAFQALSEDLVIKRPHYT------------------YSV-SETDDGNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-NIVESDQFESIWWDETGTCIVINEELFKKEVLERKDPFRIFETKSMKT
LIRQLNLYGFHKNRQTVQRSASLPVFLEEENNI--SLLS-----KLQTYYN-PNFKRGHP
QLLVRMQRRVGINNVSPIS-SLVQG--------------NKK-HA-KASV---KKDDLNS
EFLPEMSGES--------------AFPAST------------------------------
----------------------------SLSVPFMQKPHTSQIVTNTSALSP--CDLPTP
S-AISVRHTDQIVVDQSEVLKKL---SIFNWHSQSSYTQVNGHVEDFATTTTSTSRNHIE
SPLQS-----SYSGLMVKPS--KFPDRHS--DMSAHDSPFL-------NLQERGNSWFPV
PTIAYTSASSLSSKLINNHHYVK--TILIKTDLSNTCQIME---PK--------GD----
----

-------------MATQSIE-----EDCE-TNGNPAVDEEPESK----DIP-NSSPGSEA
HSREGLVRQDDQNVIQDQ-----------S--------------QPA-ASEEDNTNLLSL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 246)

FPRKL----W-AIVQNDAFKSVNWTKDGDSILIEVDLFQREVLHLKGAKKIFETDSLKS
FIRQLNLYGFRKISSETS-----------------VASS-GENKKIMIYRN-FNFQRDKP
GLFKYIWGKEDLGNLAKQATCVPIPLSPSQGPIS-----KKKKMS-PTRY--------SP
RFYCKPEED---------------------GVESG-------------------------
-----------------------------K------KNSNNQAHKGNHSFVF--SSVWAM
---------KAI--PGYYLQNQP-------------SGEPSNTT------VEDTSHNIRM
PPTAP------GVQGTEVPSAS--SPGHR--ILH--------------SMMSLYNDCCSA
IFSALSQRPMNESPIE------E--EQEGSSD--YKRVICEPIKNNPHL-----------
----

-------------MAH------APSEIQPVSPKDAPTGSDSSTTS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRMKNASPVSASLLQG--------------CSKKRS-RTGG---NVDNHNS
DVAAETRGED--------------AFSAST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTTTPTR--SGLSSP
S-SPSVRPPGQIAMAQHAIFSQL---TTFHMHSQSSYSPASGHIVNFITTTTSISQYHLI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTEGPLS-------NPQPAAHPWFPM
PMATDTSVASLSRPNPQSSSVSE--HHPNYH-----------------------------
----

-------------MAH------ISSEIQDGPPKDESTDSETSIRS---SLY-DYT-TGDS
VLRSMIEEYAFQALSEDLVIKRPHYT------------------YSV-SETDDGNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 197)

FPRKL----W-NIVESDQFESIWWDETGTCIVINEELFKKEVLERKDPFRIFETKSMKS
FIRQLNLYGFHKNRQSVQRSASLPVFLEEENNI--SL-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MAH------IPSEIQDMPPKDESTGSGTSIRS---TLC-DYTLTEDS
VLRSMIEEDAFKALFEEVVIKMPRYK------------------FSV-SETDELNDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-KLVESDQFKSIWWDESGTSVVINEEVFKKEVLERKAPFRIFETDSMKS
LVRQLNLYGFKKKQHTFQRSASLADFLEEKSNV--SVLS-----KLQIYHN-PNFKRGYP
QLLLRMKRRIGIKNVSPIA-SLIQD--------------YKKKNV-IARG---NIDNCNS
SSPPETSGES--------------AFSASV------------------------------
----------------------------SLSVPF--TPYTRQTVDNTSALSP--CDFPSP
S-STSVRQTENIVMDQPAILNQL---SIFNRLSHSSYTEANGLMENFATTTTSASQNHIV
SPLQS-----SYVGLMVHPS--KFPVRYS--YMTAHDSPFP-------NLQQRGNSWSPV
PRIHDTSSSSLSRSTHQKSSLYE--NH------PN-------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSEVLDRHEDHAVSQDPGSQDNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEETFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDKP
RLLENIQRKDDLRNTAQQATCVPTP--------------KRKKLV-ATRR--------SL
RIHHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------GAPNVQGPSGTQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPS------WEGTSGNVTF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLCNICYSI
LLATLSVMSPNEPSDN-----DE--EQEDSSD--YKCKLCEQFRNNASP-----------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSEVLDRHEDHAVSQDPGSQDNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEDTFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDKP
RLLENIQRKDDLRNTAQQATCVPPP--------------KRKKLV-ATRR--------SL
RIYHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------GAPNVQGPSGTQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPS------WEGTSGNVTF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLCNICYSI
LLATLSVMSPNEPSDN-----DE--EQEGSSD--YKCKLCEQFRNNASP-----------
----

------------------------------------------------------GSLGDS
ELRELVEEAAFQTLAEEPLVKRHHYS------------------SCD-AGSVNDNQLHFL

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 248)

TFSKKL----W-KLVESDEFKSISWDDDGNFVVINEELFKTEVLGRKGPLKIFETECMKS
FIQQLNSYGFNKLQLDFQRSASLAEFLAEENEV--SALS-----KLQFYYS-PNFQRQFP
ELMKKIKR-LGVNNGYSPTVN---------------------QMT-RKTT--EKMQDQIA
ASQ-------------PTGKKSSS---KPPNENQQKSNDK--------------------
----TPAKNKKPDPTRPQPESCP--SVA--------------------------------
Q-AISVKTAESVAAGENGRLNQP-ELAPIHVQQSN-PTPVNAQNVV-LPVVT-SPVYHII
PASQD-----SSFSSVIGIP--AFQIIYP--NLLVVPTNLP-------DGLPVYNSWLSV
PVIAAPPATPMASDPQ---------------GIHHHCPTCNCFANNVSAPAGPPESTGAT
G---

-------------MASQNME-----DKCE-DMQAPTIGGEPENW----VPP-DTSTDPEV
ESKEDMDEHRDEDASQNQGSQDNVQSEDQN--------------ENV-ADVTDNINFSGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-MIVENKVFKSVNWSDKGDTMVIEEDLFQREILRRRGTEKIFETDSLKS
FIRQLNLYGFRKIRSNNS-----------------SVPS-QGEKKMMVYQH-SNFQRDKP
HLLEKIQKKGYFRNTTLEAAGGPAM--------------KKKKLV-ATRH--------SL
RIRQNNAKKE----------------A---KQKSQ-------------------------
-----------------------------K------GAPSVQGTSGTQSFMC--SGISSM
---------RST--TGYPQGNRS-------------TFEPHGPS------GEGASSSATF
TPIAT-----ARMESTREGSAS--PEVYP--EYD--------------SILTLYNTCYAI
LLAALSVMGPNEPPES------E--EPEGPSD--YKCALCERFKDNPNP-----------
----

---------------LVGVP-----TRHT-APLAPSTDGKPT------------------
----VLAKQGDQPESLDL---------------------------ET-ANKEENNTVLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEDAAFTCVHWN-KGDTVVIKADLFQTEVLQGRGMDRIFETDSIQS
FICELNLYEFSKIHPS--------------------GSS-VGKKRMMIYHS-SNFQRDKP
LFLQNIQTKGNPITTAQPATGS--------------------------------------
-------TQE----------------A---DKKAQ-------------------------
-----------------------------K------GAPAAHGTHGRHSFVF--CGLWFM
---------GSV--AVQAGANHL-------------PREQGSPS------GEGTSSNATS
VPPAT-----AGRDTTGELSES--LPEYP--GYG--------------SVMIMYSIYYSI
VTAAVSVVAPNEAPEV-----EE--EQ-ESSD--YKCALCEQFENNPSP-----------
----

-------------MAH------ISSEIQDGPPKDESTGSETSIRS---SLY-DYT-TGDS
VLRSMIEEYAFQALSEDLVIKRPHYT------------------YSV-SETDDANDFLSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPQKL----W-NIVESDQFESIWWDDTGTCIVINEELFKKEVLERKEPFRIFETKSMKS
FIRQLNLYGFHKNRQSVQRSASLPVFLEEENNI--SLLS-----KLQTYYN-PSFKRGHP
QLLVRMQRRVGINNVSPIS-SLVQG--------------NKK-RA-KASV---KKDDHNS
EFIPEMEWRE--------------RISSLH------------------------------
----------------------------KFKCAFHTKASYQPDSH---------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

-------------MASQNTE-----QEYE-DKLAPSVGGEPTSG----DPF-SSSPDPNP
DSSEVLDRHEDHAVSQDPGSQVNSPPEDRN--------------QCV-VNTEDNQNLFRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-MIVEEETFKSVSWNDDGDAVIIEKDLFQREVLQRRGAERIFETDSLKS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYHN-SNFQRDKP
RLLENIQRKDDLRNTAQQATCVPTP--------------KRKKLV-ATRR--------SL
RIYHINAKKE----------------A---IKMCQ-------------------------
-----------------------------R------GAPNVQGPSGTQSFMF--SGMWSK
---------NSI--TGHPLGNRP-------------PQEPNGPS------WEGTSGNVTF
ASSAT-----AWMEGIGQVPSS--P-VYS--DNG--------------SVLSLYNICYSI
LLATLSVMSPNEPSDN-----DE--EQEGSSD--YKCKLCEQFRNNASP-----------
----

-------------MDEFELD-STSSENPDTSPRARTTDSETCGGSKLSPEC-EQTSAGDC
DLRSVIEENVFQPLAEGPLVKKRRYI------------------W---PDGSDSNDFFAF

PF00447 // ENSGT00510000047153_1_Domain_0 (121, 250)

TFPKKL----W-KIIESDQFQSIWWNNDGNSIVIDEELFKKEVLESKGPFRIFETDCMKS
FIRQLNLYGFSKIRYEFQRSASLADFLAEEKAV--SAMN-----KLQFYHN-PNFKRGCP
HLLVRLKRRVGIKNAAPVSFSFFQE--------------Y------PKTT--ENPNGQNV
AS--------------PVEAIEKNVFSTSPNEEGQKS-----------------------
-------------------------S---------VKFTLSKRQISATPQIR--SGFSAP
P-ATSVRPPEHSVSEQNATHNQL---APILLPQQSCLAQANARDIDSVTTSA-TSLYRVM
PPVRS-----SPFGPVMGLP--SFPPAYP--ELSSVQAHLA-------SLLPFCNPWLSM
HMLAAASAISMSRAPS----------HHHQTPSNYHCPNCNCSASNAPTPP--PNGPPSS
GE--

-------------MAH------APSEIQGVSPKDESTGSESSITS---PWC-DNSITGDL
DLRSQIEEKAFQALSEGSLMKEPCHT------------------LCA-SEPDGDNDFPPL
P

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-EIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKS
LVRQLNLYGFTKLRRNFQRPASLANILAEDNEV--SAWN-----KLQFYHN-PNFKRGCP
HLLVRMKRRVRMKNASPVSASLLHG--------------CSKKRS-RTGG---DVDNHNS
DVAAETRGED--------------AFSTST------------------------------
----------------------------NLNVPLIRWPSMSQRISNTSTPTR--SGLSSP
S-SPSFRPPGQIVMAQHAIFSQL---TTFHMHSQSSYSPASGHVVNFITTTTSISQYRCI
SNFPS-----GYFGLRVEPS--PLPTRYQ--NISPTECPVS-------NPQPAAHPWFPM
PMATDTSAASLSRPNPQTSSVSE--HHPNYH-----------------------------
----

-------------MASQNTE-----QEYE-AKLAPSVGGEPTSG----GPS-GSSPDPNP
DSSEVLDRHEDQAMSQDPGSQDNSPPEDRN--------------QRV-VNMEDNHNLFRL
F

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-TIVEEDTFKSVSWNDDGDAVIIDKDLFQREVLQRRGAERIFKTDSLTS
FIRQLNLYGFCKTRPSN---------------------S-PGNKKMMIYCN-SNFQRDKP
RLLENIQRKDARRNTAQQATRVPTT--------------KRKNLV-ATRR--------SL
RIYHINARKA----------------A---IKMCQ-------------------------
-----------------------------Q------GAPSVQGPSGTQSFRR--SGMWSK
---------KSA--TRHPLGNGP-------------PQEPNGPS------WEGTSGNVTF
TSSAT-----TWMEGTG-IPSS--L-VYS--DNG--------------SEMSLYNICYYA
LLASLSVMSPNEPSDD-----EE--E----------------------------------
----

-------------MDSHS-------SHKA-VLLAPSTDGEPTAG----DPH-DSSPDPNV
DSGEALEKQGDQPKSPDLGLHDNLLPQGPN--------------PEM-ANKEENNTVLGL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-RIVEDATFTSVHWNDKGDTVVIEADLFQMEVLQHRGVDQIFETDSIKS
FIRELNLYGFRKIRPS--------------------GCC-AGKKKMMIYHN-SNFQRDKP
LLLQNIQRKGDPRTTSQPATGTTAT-------------PKRKKRVVATTY--------SP
QLHHNEFTKE----------------G---GNKVQ-------------------------
-----------------------------E------GMPTAHRTLSQCSFVF--SDFGSM
---------GSV--ARQAGGNHL-------------PSEQGSPS------GKGTSSNATS
VPPAT-----AGRDSPGELPES--ALVYP--DYE--------------SVMTLYNTCYSI
LMAGLLVMAPDEAPES-----EE--EQGDSSD--YKCALCEQVKNKPNP-----------
----

------------------------------------------------------------
------------------------------------------------------------
TFPEKL----W-VLVESHQFKSIWWGQNGSCIVIDQEICQVEVLGKKGSLTVLETESMK

PF00447 // ENSGT00510000047153_1_Domain_0 (180, 194)

S
FIRQLNMYGFTKMQCDSRRSPSLPEFLAEEEAF--VVHR-----KLLCYYN-PYFRNNHP
DLLELCKHRVIQKRRAVAAPNPQEQ--------------LNEE-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

---------TVGIESELSTV------GTSADSSDPEGLAVSPGSPSDR-LGQEK---GTA
-WASKMDEKNVLTYPHQEEIICLPHA------------------SYEESTHRGTITSTAS
TFPEKL----W-VLVESHQFKSIWWGQNGSCIVIDQEIFQVEVLGKKGSLRVFGTESMK

PF00447 // ENSGT00510000047153_1_Domain_0 (180, 195)

S
FIRQLNMYGFTKMQ

ENSGT00510000047153_1_Linker_0_1 (195, 233)

RDSRRSPSLPEFLAEEEAF--VAHR-----KLLCYYS-

PF00447 // ENSGT00510000047153_1_Domain_1 (233, 249)

PYFRKDHP
ELLKLCKRR---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----

------------------------------------------------------------
-----MDEKNALTYPHQAEIKCIPHV------------------SHEESTCTDTVISAAL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPEKL----W-VLVESHQFKSIWWGQNGSCVVIDQEMFQIEVLGKKGSLRVFGTESTKS
FIRQLHAYGFTKMQRDSKRSASLPEFLAEEEAF--AAHR-----KLLCYHN-PYFRKDHP
ELLELCKRRVAQKRRAVAAPNPQEE--------------LNEGLP-RSSPDAQPMEGTAA
GP-----EKS------LLT--------ADPEAGTQ-------------------------
------AVPSMGPPPPKQPKKSPTQAQA-GSAPTLPDPVAAPGREECQP-----------
-------------------LA-------------RSPLPPNSSPISGA-TSA-PPAYNAL
PFKA---------------------PTFT--SGSVWQAPLESELQDPGAALHYLSQCFAM
AMLAAAKMTSANWGPWAVSHYPT--CTCSSHKAAPHCPTCTCGSDGVDAGER--LAP---
----

-------------MVIQSSH-----ETCT-ALLAPSTDGEATAG-----------PDPNV
DSGEALEKLWDQPESPDL-P-NNTPRQGLN--------------PET-ANEEENNAFLRL
S

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 280)

FPRKL----W-MIVENAAFTSVHWNDEGDMVVIEADLFQMEVFQRRGTDRIFT-DSIKT
FIHKLNLY--SKICPS--------------------GCS-AGKKRMMIYRN-SKFQRDKP
LLLQDI-----------------SA-------------PKRKKQVVVTRY--------SP
RFHHNESTQE----------------A---DKKVQ-------------------------
-----------------------------K------GAPNVHRIPGRCSFLF--CGLWFI
---------GSV--AGQAKENHL-------------PRELGGPS------GEGMSSNSMS
VSPAT-----AGRDSAGQLPKS--PPRYP--DYV--------------SVMNLYNTYDSI
MKVAILVVAPSEAPEA-----DE--KEEECSD--YTCALCEQFKDNPNP-----------
----

-------------MEH------GSSETQGFSPKDELTVSEASTRS---PLC-EHTFSGDS
DLRSMIEENAFQVLSQGFLLKRPCYT------------------VCV-SEPDKDNDFFSL
T

PF00447 // ENSGT00510000047153_1_Domain_0 (122, 249)

FPRKL----W-KIVESDQFKSVSWDENGTCIMINEELFKKEILERKHPYRIFQTDSIRS
FVRQLNIYGFSKIRQNFQRSAFLPTFLAEEKES--SVLT-----KLKCYYN-PHFKRGCP
QLLVRVKRRIDVKNASLTPTLFHED--------------FNQKHF-RAGA---NMENHNP
ALAAEVSEES--------------LFATST------------------------------
----------------------------NLNMSLTRESSVGKIIASSSDPII--SGFLPP
SRSTSIGPSEQSATDQRAILNQL---STIHMHSHSTYMQARGRIVNFITTTT--SQYHII
SPFQN-----CFLGLTLESP--AVPTRYP--VVSVNQAPHP-------NLLPAGNRWLQM
STIADISSSPLSRPATQPSPLDK--YHTNYN-----------------------------
----